The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1C4K9-1", "A0A8V0YKW8-1" ], "evidence": [ { "id": "R-GGA-1855165", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1855165" } ] }, { "id": "R-GGA-1855198", "name": "5-PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1C4K9-1", "A0A8V0YKW8-1" ], "evidence": [ { "id": "R-GGA-1855198", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1855198" } ] }, { "id": "R-GGA-2023971", "name": "1/3 PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1C4K9-1", "A0A8V0YKW8-1" ], "evidence": [ { "id": "R-GGA-2023971", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2023971" } ] }, { "id": "R-GGA-2023973", "name": "(PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1C4K9-1", "A0A8V0YKW8-1" ], "evidence": [ { "id": "R-GGA-2023973", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2023973" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A8V0YKW8", "gene_name": "NUDT4", "activity": [ { "ec_number": "3.6.1.52", "activity": "6-diphospho-1D-myo-inositol pentakisphosphate + H2O = 1D-myo-inositol hexakisphosphate + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YKW8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKW8" } ] }, { "ec_number": "3.6.1.52", "activity": "", "evidence": [ { "id": "A0A8V0YKW8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKW8" } ] } ] }, { "uniprot_ac": "E1C4K9", "gene_name": "NUDT3", "activity": [ { "ec_number": "3.6.1.52", "activity": "6-diphospho-1D-myo-inositol pentakisphosphate + H2O = 1D-myo-inositol hexakisphosphate + phosphate + H(+).", "evidence": [ { "id": "E1C4K9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C4K9" } ] }, { "ec_number": "3.6.1.52", "activity": "", "evidence": [ { "id": "E1C4K9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C4K9" } ] } ] } ], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1C4K9-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 169, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1C4K9-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1C4K9" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1C4K9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C4K9" }, { "id": "PS51462", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51462" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Nudix hydrolase", "eco_id": "ECO_0000259", "start_pos": 17, "end_pos": 142, "start_aa": "Tyr", "end_aa": "Thr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "3.6.1.52", "ec_name": "6-diphospho-1D-myo-inositol pentakisphosphate + H2O = 1D-myo-inositol hexakisphosphate + phosphate + H(+).", "evidence": [ { "id": "3.6.1.52", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.1.52" }, { "id": "3.6.1.52", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=3.6.1.52" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 151, "end_pos": 153 }, { "start_pos": 7, "end_pos": 9 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BQT2-1", "uniprot_ac": "E1BQT2", "uniprot_id": "E1BQT2_CHICK", "mass": { "chemical_mass": 228288.0, "monoisotopic_mass": 228288.0 }, "refseq": { "ac": "NP_001280210", "name": "sodium channel protein type 2 subunit alpha", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001280210" }, "gene_names": [ { "name": "SCN2A", "type": "recommended", "evidence": [ { "id": "E1BQT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQT2" } ] }, { "name": "SCN2A", "type": "synonym", "evidence": [ { "id": "NP_001280210", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001280210" } ] } ], "protein_names": [ { "name": "Sodium channel protein", "type": "recommended", "evidence": [ { "id": "E1BQT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQT2/entry#names_and_taxonomy" } ] }, { "name": "sodium channel protein type 2 subunit alpha", "type": "synonym", "evidence": [ { "id": "NP_001280210", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001280210" } ] }, { "name": "sodium channel, voltage-gated, type II, alpha subunit", "type": "synonym", "evidence": [ { "id": "NP_001280210", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001280210" } ] }, { "name": "voltage-gated sodium channel II", "type": "synonym", "evidence": [ { "id": "NP_001280210", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001280210" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## RNAseq introns :: mixed sample support SAMEA103992290, SAMEA103992323 [ECO:0006172] ##Evidence-Data-END## ##RefSeq-Attributes-START## inferred exon combination :: based on alignments, homology ##RefSeq-Attributes-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000236.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001280210", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001280210" } ] }, { "annotation": "Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.", "evidence": [ { "database": "UniProtKB", "id": "E1BQT2", "url": "https://www.uniprot.org/uniprotkb/E1BQT2#function" }, { "database": "UniProtKB", "id": "RU361132", "url": "https://www.uniprot.org/uniprotkb/RU361132#function" }, { "database": "UniProtKB", "id": "A0A8V1A5Z8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5Z8#function" }, { "database": "UniProtKB", "id": "A0A8V1A605", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A605#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1BQT2", "url": "https://www.uniprot.org/uniprotkb/E1BQT2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SCN2A", "url": "https://www.uniprot.org/uniprotkb/E1BQT2", "locus": { "chromosome": "7", "start_pos": 19439332, "end_pos": 19512749, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010025597", "url": "https://www.ensembl.org/id/ENSGALG00010025597" } ] } } ], "crossref": [ { "id": "ENSGALG00000011009", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000011009", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd13433", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13433", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "395945", "url": "https://www.ncbi.nlm.nih.gov/gene/395945", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000048", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000048", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001696", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001696", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005821", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005821", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR010526", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010526", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024583", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024583", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027359", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027359", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043203", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043203", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044564", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044564", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR058542", "url": "https://www.ebi.ac.uk/interpro/entry/IPR058542", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:395945", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:395945", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "ISVIPXH", "url": "https://omabrowser.org/oma/group/ISVIPXH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A5Z8", "url": "https://www.orthodb.org/?gene=A0A8V1A5Z8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A605", "url": "https://www.orthodb.org/?gene=A0A8V1A605", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1BQT2", "url": "https://www.orthodb.org/?gene=E1BQT2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10037", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10037", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10037:SF278", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10037:SF278", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00520", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00520", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF06512", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06512", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF11933", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11933", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24609", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24609", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:E1BQT2", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:E1BQT2", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_001280210", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001280210", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "34963", "url": "https://www.rhea-db.org/rhea/34963", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V1A5Z8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5Z8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A5Z8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5Z8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A605", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A605", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A605-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A605-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BQT2", "url": "https://www.uniprot.org/uniprotkb/E1BQT2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BQT2-1", "url": "https://www.uniprot.org/uniprotkb/E1BQT2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAQSVLVPPGPDSFRYFTRESLAAIEQRINEEKAKKSKQERKDDDDEDGPKPNSDLEAGKTLPFIYGDIPPGMVSEPLEDLDPYYINKKTFIVLNKGKAIFRFSATSALYMLTPFNPLRKIAIKILVHSLFSMLIMCTILTNCVFMTMSNPPDWTKNVEYTFTGIYTFESLIKILARGFCLEDFTFLRDPWNWLDFTVITFAYVTEFVDLGNVSALRTFRVLRALKTISVIPGLKTIVGALIQSVKKLSDVMILTVFCLSVFALIGLQLFMGNLRNKCLQWPPDNSTFETTVITYFNSSIGENGTFINTTMTIFNWDEYIEDENHFYFLEGQNDALLCGNSSDAGQCPEGYICVKAGRNPNYGYTSFDTFSWAFLSLFRLMTQDFWENLYQLTLRAAGKTYMIFFVLVIFLGSFYLINLILAVVAMAYEEQNQATMEEAEQKEAEFQQMLEQLKKQQEEAQAAAAAAAADSRDYSGVGGIGGFSESSSEASKLSSKSAKERRNRRKKKKQKEQAEGEKDEEEFRKSESEDSIKRKGFRFSIEGNRLTYEKRFSSPHQSLLSIRGSLFSPRRNSRTSLFSFRGRAKDVGSENDFADDEHSTFEDNESRRDSLFVPHRHGERRNSNISQASRSSRTVPPLPVNGKMHSTVDCNGVVSLVGGPPALTSPTGQLLPEGTTTETDLRKRRSSSYQVPMDYLTDPSARQRAMSIASMLTNTMEELEESRQKCPPCWYKFANTCLIWDCCTPWLKVKHIVNLIVMDPFVDLAITICIVLNTLFMAMEHYPMTEQFSGVLSVGNLVFTGIFTAEMFLKIIAMDPYYYFQEGWNIFDGFIVSLSLMELGLANVEGLSVLRSFRLLRVFKLAKSWPTLNMLIKIIGNSVGALGNLTLVLAIIVFIFAVVGMQLFGKSYKECVCKISSDCELPRWHMHDFFHSFLIVFRVLCGEWIETMWDCMEVAGQTMCLTVFMMVMVIGNLVVLNLFLALLLSSFSSDNLAATDDDNEMNNLQIAVARIQKGIDFVKRKVREFIQKAFVRKQKVLDEIKPLEDLNNKKDSCISNHTIVEIGKNLAYLKEGNGTTSGIGSSVEKYVVDESDYMSFINNPSLTVTVPIAVGESDFENLNTEEFSSESDLEESKEKLNASSSSEGSTVDIGLPPEGEQPEVEPEESLEPEACFTEGCVRRFKCCQVSVEDGKGKIWWNLRKTCYKIVEHNWFETFIVFMILLSSGALAFEDIYIEQRKTIKTMLEYADKVFTYIFILEMLLKWVAYGFQTYFTNAWCWLDFLIVDVSLVSLTANALGYSELGAIKSLRTLRALRPLRALSRFEGMRVVVNALLGAIPSIMNVLLVCLIFWLIFSIMGVNLFAGKFYYCVNTTTDERFDISQINNYSQCEELIKNNETARWKNVKVNFDNVGLGYLSLLQVATFKGWMDIMYAAVDSRNVLDQPKYEDNLYMYLYFVIFIIFGSFFTLNLFIGVIIDNFNQQKKKFGGQDIFMTEEQKKYYNAMKKLGSKKPQKPIPRPANKFQGMVFDFVTKQAFDISIMILICLNMVTMMVETDDQSEDMENILYWINLVFIVLFTGEFVLKLISLRHYYFTIGWNIFDFVVVILSIVGMFLAEMIEKYFVSPTLFRVIRLARIGRILRLIKGAKGIRTLLFALMMSLPALFNIGLLLFLVMFIYAIFGMSNFAYVKREVGIDDMFNFETFGNSMICLFQITTSAGWDGLLAPILNSGEPDCDPHKDHPGSSVKGDCGNPSVGIFFFVSYIIISFLVVVNMYIAVILENFSVATEESAEPLSEDDFEMFYEVWEKFDPDATQFIEFSKLSDFAASLDPPLLIAKPNKVQLIAMDLPMVSGDRIHCLDILFAFTKRVLGESGEMDALRIQMEDRFMAANPSKVSYEPITTTLKRKQEEVSAVVIQRAFRRHLLRQKVKKVSCIFNQDKGKDEDDLPMKEDMIMDKLNENSTPEKTDMTPSTTSPPSYDSVTKPDKDKYEKDKSEKEDKGKDSRESKK", "length": 2006, "header": "tr|E1BQT2-1|E1BQT2_CHICK Isoform 1 of Sodium channel protein OS=Gallus gallus OX=9031 GN=SCN2A PE=3 SV=3 CANONICAL=E1BQT2-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A5Z8-1", "url": "https://www.uniprot.org/uniprotkb/E1BQT2/entry#A0A8V1A5Z8-1", "sequence": { "sequence": "MAQSVLVPPGPDSFRYFTRESLAAIEQRINEEKAKKSKQERKDDDDEDGPKPNSDLEAGKTLPFIYGDIPPGMVSEPLEDLDPYYINKKTFIVLNKGKAIFRFSATSALYMLTPFNPLRKIAIKILVHSLFSMLIMCTILTNCVFMTMSNPPDWTKNVEYTFTGIYTFESLIKILARGFCLEDFTFLRDPWNWLDFTVITFAYVTEFVNLGNVSALRTFRVLRALKTISVIPGLKTIVGALIQSVKKLSDVMILTVFCLSVFALIGLQLFMGNLRNKCLQWPPDNSTFETTVITYFNSSIGENGTFINTTMTIFNWDEYIEDENHFYFLEGQNDALLCGNSSDAGQCPEGYICVKAGRNPNYGYTSFDTFSWAFLSLFRLMTQDFWENLYQLTLRAAGKTYMIFFVLVIFLGSFYLINLILAVVAMAYEEQNQATMEEAEQKEAEFQQMLEQLKKQQEEAQAAAAAAAADSRDYSGVGGIGGFSESSSEASKLSSKSAKERRNRRKKKKQKEQAEGEKDEEEFRKSESEDSIKRKGFRFSIEGNRLTYEKRFSSPHQSLLSIRGSLFSPRRNSRTSLFSFRGRAKDVGSENDFADDEHSTFEDNESRRDSLFVPHRHGERRNSNISQASRSSRTVPPLPVNGKMHSTVDCNGVVSLVGGPPALTSPTGQLLPEVMIDKATTASNGTTTETDLRKRRSSSYQVPMDYLTDPSARQRAMSIASMLTNTMEELEESRQKCPPCWYKFANTCLIWDCCTPWLKVKHIVNLIVMDPFVDLAITICIVLNTLFMAMEHYPMTEQFSGVLSVGNLVFTGIFTAEMFLKIIAMDPYYYFQEGWNIFDGFIVSLSLMELGLANVEGLSVLRSFRLLRVFKLAKSWPTLNMLIKIIGNSVGALGNLTLVLAIIVFIFAVVGMQLFGKSYKECVCKISSDCELPRWHMHDFFHSFLIVFRVLCGEWIETMWDCMEVAGQTMCLTVFMMVMVIGNLVVLNLFLALLLSSFSSDNLAATDDDNEMNNLQIAVARIQKGIDFVKRKVREFIQKAFVRKQKVLDEIKPLEDLNNKKDSCISNHTIVEIGKNLAYLKEGNGTTSGIGSSVEKYVVDESDYMSFINNPSLTVTVPIAVGESDFENLNTEEFSSESDLEESKEKLNASSSSEGSTVDIGLPPEGEQPEVEPEESLEPEACFTEGCVRRFKCCQVSVEDGKGKIWWNLRKTCYKIVEHNWFETFIVFMILLSSGALAFEDIYIEQRKTIKTMLEYADKVFTYIFILEMLLKWVAYGFQTYFTNAWCWLDFLIVDVSLVSLTANALGYSELGAIKSLRTLRALRPLRALSRFEGMRVVVNALLGAIPSIMNVLLVCLIFWLIFSIMGVNLFAGKFYYCVNTTTDERFDISQINNYSQCEELIKNNETARWKNVKVNFDNVGLGYLSLLQVATFKGWMDIMYAAVDSRNVLDQPKYEDNLYMYLYFVIFIIFGSFFTLNLFIGVIIDNFNQQKKKFGGQDIFMTEEQKKYYNAMKKLGSKKPQKPIPRPANKFQGMVFDFVTKQAFDISIMILICLNMVTMMVETDDQSEDMENILYWINLVFIVLFTGEFVLKLISLRHYYFTIGWNIFDFVVVILSIVGMFLAEMIEKYFVSPTLFRVIRLARIGRILRLIKGAKGIRTLLFALMMSLPALFNIGLLLFLVMFIYAIFGMSNFAYVKREVGIDDMFNFETFGNSMICLFQITTSAGWDGLLAPILNSGEPDCDPHKDHPGSSVKGDCGNPSVGIFFFVSYIIISFLVVVNMYIAVILENFSVATEESAEPLSEDDFEMFYEVWEKFDPDATQFIEFSKLSDFAASLDPPLLIAKPNKVQLIAMDLPMVSGDRIHCLDILFAFTKRVLGESGEMDALRIQMEDRFMAANPSKVSYEPITTTLKRKQEEVSAVVIQRAFRRHLLRQKVKKVSCIFNQDKGKDEDDLPMKEDMIMDKLNENSTPEKTDMTPSTTSPPSYDSVTKPDKDKYEKDKSEKEDKGKDSRESKK", "length": 2017, "header": "tr|A0A8V1A5Z8-1|A0A8V1A5Z8_CHICK Computationally mapped isoform of Sodium channel protein OS=Gallus gallus OX=9031 GN=SCN2A PE=3 SV=1 CANONICAL=E1BQT2-1" }, "locus": { "chromosome": "7", "start_pos": 19494804, "end_pos": 19441468, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010062468.1", "url": "https://www.ensembl.org/id/ENSGALT00010062468.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038628.1", "url": "https://www.ensembl.org/id/ENSGALP00010038628.1" } ] } }, { "isoform_ac": "A0A8V1A605-1", "url": "https://www.uniprot.org/uniprotkb/E1BQT2/entry#A0A8V1A605-1", "sequence": { "sequence": "MAQSVLVPPGPDSFRYFTRESLAAIEQRINEEKAKKSKQERKDDDDEDGPKPNSDLEAGKTLPFIYGDIPPGMVSEPLEDLDPYYINKKTFIVLNKGKAIFRFSATSALYMLTPFNPLRKIAIKILVHSLFSMLIMCTILTNCVFMTMSNPPDWTKNVEYTFTGIYTFESLIKILARGFCLEDFTFLRDPWNWLDFTVITFAYVTEFVNLGNVSALRTFRVLRALKTISVIPGLKTIVGALIQSVKKLSDVMILTVFCLSVFALIGLQLFMGNLRNKCLQWPPDNSTFETTVITYFNSSIGENGTFINTTMTIFNWDEYIEDENHFYFLEGQNDALLCGNSSDAGQCPEGYICVKAGRNPNYGYTSFDTFSWAFLSLFRLMTQDFWENLYQLTLRAAGKTYMIFFVLVIFLGSFYLINLILAVVAMAYEEQNQATMEEAEQKEAEFQQMLEQLKKQQEEAQAAAAAAAADSRDYSGVGGIGGFSESSSEASKLSSKSAKERRNRRKKKKQKEQAEGEKDEEEFRKSESEDSIKRKGFRFSIEGNRLTYEKRFSSPHQSLLSIRGSLFSPRRNSRTSLFSFRGRAKDVGSENDFADDEHSTFEDNESRRDSLFVPHRHGERRNSNISQASRSSRTVPPLPVNGKMHSTVDCNGVVSLVGGPPALTSPTGQLLPEVMIDKATTASNGTTTETDLRKRRSSSYQVPMDYLTDPSARQRAMSIASMLTNTMEELEESRQKCPPCWYKFANTCLIWDCCTPWLKVKHIVNLIVMDPFVDLAITICIVLNTLFMAMEHYPMTEQFSGVLSVGNLVFTGIFTAEMFLKIIAMDPYYYFQEGWNIFDGFIVSLSLMELGLANVEGLSVLRSFRLLRVFKLAKSWPTLNMLIKIIGNSVGALGNLTLVLAIIVFIFAVVGMQLFGKSYKECVCKISSDCELPRWHMHDFFHSFLIVFRVLCGEWIETMWDCMEVAGQTMCLTVFMMVMVIGNLVVLNLFLALLLSSFSSDNLAATDDDNEMNNLQIAVARIQKGIDFVKRKVREFIQKAFVRKQKVLDEIKPLEDLNNKKDSCISNHTIVEIGKNLAYLKEGNGTTSGIGSSVEKYVVDESDYMSFINNPSLTVTVPIAVGESDFENLNTEEFSSESDLEESKEKLNASSSSEGSTVDIGLPPEGEQPEVEPEESLEPEACFTEGCVRRFKCCQVSVEDGKGKIWWNLRKTCYKIVEHNWFETFIVFMILLSSGALAFEDIYIEQRKTIKTMLEYADKVFTYIFILEMLLKWVAYGFQTYFTNAWCWLDFLIVDVVVNALLGAIPSIMNVLLVCLIFWLIFSIMGVNLFAGKFYYCVNTTTDERFDISQINNYSQCEELIKNNETARWKNVKVNFDNVGLGYLSLLQVATFKGWMDIMYAAVDSRNVLDQPKYEDNLYMYLYFVIFIIFGSFFTLNLFIGVIIDNFNQQKKKFGGQDIFMTEEQKKYYNAMKKLGSKKPQKPIPRPANKFQGMVFDFVTKQAFDISIMILICLNMVTMMVETDDQSEDMENILYWINLVFIVLFTGEFVLKLISLRHYYFTIGWNIFDFVVVILSIVGMFLAEMIEKYFVSPTLFRVIRLARIGRILRLIKGAKGIRTLLFALMMSLPALFNIGLLLFLVMFIYAIFGMSNFAYVKREVGIDDMFNFETFGNSMICLFQITTSAGWDGLLAPILNSGEPDCDPHKDHPGSSVKGDCGNPSVGIFFFVSYIIISFLVVVNMYIAVILENFSVATEESAEPLSEDDFEMFYEVWEKFDPDATQFIEFSKLSDFAASLDPPLLIAKPNKVQLIAMDLPMVSGDRIHCLDILFAFTKRVLGESGEMDALRIQMEDRFMAANPSKVSYEPITTTLKRKQEEVSAVVIQRAFRRHLLRQKVKKVSCIFNQDKGKDEDDLPMKEDMIMDKLNENSTPEKTDMTPSTTSPPSYDSVTKPDKDKYEKDKSEKEDKGKDSRESKK", "length": 1976, "header": "tr|A0A8V1A605-1|A0A8V1A605_CHICK Computationally mapped isoform of Sodium channel protein OS=Gallus gallus OX=9031 GN=SCN2A PE=3 SV=1 CANONICAL=E1BQT2-1" }, "locus": { "chromosome": "7", "start_pos": 19494804, "end_pos": 19441468, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010062473.1", "url": "https://www.ensembl.org/id/ENSGALT00010062473.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038633.1", "url": "https://www.ensembl.org/id/ENSGALP00010038633.1" } ] } }, { "isoform_ac": "E1BQT2-1", "url": "https://www.uniprot.org/uniprotkb/E1BQT2/entry#E1BQT2-1", "sequence": { "sequence": "MAQSVLVPPGPDSFRYFTRESLAAIEQRINEEKAKKSKQERKDDDDEDGPKPNSDLEAGKTLPFIYGDIPPGMVSEPLEDLDPYYINKKTFIVLNKGKAIFRFSATSALYMLTPFNPLRKIAIKILVHSLFSMLIMCTILTNCVFMTMSNPPDWTKNVEYTFTGIYTFESLIKILARGFCLEDFTFLRDPWNWLDFTVITFAYVTEFVDLGNVSALRTFRVLRALKTISVIPGLKTIVGALIQSVKKLSDVMILTVFCLSVFALIGLQLFMGNLRNKCLQWPPDNSTFETTVITYFNSSIGENGTFINTTMTIFNWDEYIEDENHFYFLEGQNDALLCGNSSDAGQCPEGYICVKAGRNPNYGYTSFDTFSWAFLSLFRLMTQDFWENLYQLTLRAAGKTYMIFFVLVIFLGSFYLINLILAVVAMAYEEQNQATMEEAEQKEAEFQQMLEQLKKQQEEAQAAAAAAAADSRDYSGVGGIGGFSESSSEASKLSSKSAKERRNRRKKKKQKEQAEGEKDEEEFRKSESEDSIKRKGFRFSIEGNRLTYEKRFSSPHQSLLSIRGSLFSPRRNSRTSLFSFRGRAKDVGSENDFADDEHSTFEDNESRRDSLFVPHRHGERRNSNISQASRSSRTVPPLPVNGKMHSTVDCNGVVSLVGGPPALTSPTGQLLPEGTTTETDLRKRRSSSYQVPMDYLTDPSARQRAMSIASMLTNTMEELEESRQKCPPCWYKFANTCLIWDCCTPWLKVKHIVNLIVMDPFVDLAITICIVLNTLFMAMEHYPMTEQFSGVLSVGNLVFTGIFTAEMFLKIIAMDPYYYFQEGWNIFDGFIVSLSLMELGLANVEGLSVLRSFRLLRVFKLAKSWPTLNMLIKIIGNSVGALGNLTLVLAIIVFIFAVVGMQLFGKSYKECVCKISSDCELPRWHMHDFFHSFLIVFRVLCGEWIETMWDCMEVAGQTMCLTVFMMVMVIGNLVVLNLFLALLLSSFSSDNLAATDDDNEMNNLQIAVARIQKGIDFVKRKVREFIQKAFVRKQKVLDEIKPLEDLNNKKDSCISNHTIVEIGKNLAYLKEGNGTTSGIGSSVEKYVVDESDYMSFINNPSLTVTVPIAVGESDFENLNTEEFSSESDLEESKEKLNASSSSEGSTVDIGLPPEGEQPEVEPEESLEPEACFTEGCVRRFKCCQVSVEDGKGKIWWNLRKTCYKIVEHNWFETFIVFMILLSSGALAFEDIYIEQRKTIKTMLEYADKVFTYIFILEMLLKWVAYGFQTYFTNAWCWLDFLIVDVSLVSLTANALGYSELGAIKSLRTLRALRPLRALSRFEGMRVVVNALLGAIPSIMNVLLVCLIFWLIFSIMGVNLFAGKFYYCVNTTTDERFDISQINNYSQCEELIKNNETARWKNVKVNFDNVGLGYLSLLQVATFKGWMDIMYAAVDSRNVLDQPKYEDNLYMYLYFVIFIIFGSFFTLNLFIGVIIDNFNQQKKKFGGQDIFMTEEQKKYYNAMKKLGSKKPQKPIPRPANKFQGMVFDFVTKQAFDISIMILICLNMVTMMVETDDQSEDMENILYWINLVFIVLFTGEFVLKLISLRHYYFTIGWNIFDFVVVILSIVGMFLAEMIEKYFVSPTLFRVIRLARIGRILRLIKGAKGIRTLLFALMMSLPALFNIGLLLFLVMFIYAIFGMSNFAYVKREVGIDDMFNFETFGNSMICLFQITTSAGWDGLLAPILNSGEPDCDPHKDHPGSSVKGDCGNPSVGIFFFVSYIIISFLVVVNMYIAVILENFSVATEESAEPLSEDDFEMFYEVWEKFDPDATQFIEFSKLSDFAASLDPPLLIAKPNKVQLIAMDLPMVSGDRIHCLDILFAFTKRVLGESGEMDALRIQMEDRFMAANPSKVSYEPITTTLKRKQEEVSAVVIQRAFRRHLLRQKVKKVSCIFNQDKGKDEDDLPMKEDMIMDKLNENSTPEKTDMTPSTTSPPSYDSVTKPDKDKYEKDKSEKEDKGKDSRESKK", "length": 2006, "header": "tr|E1BQT2-1|E1BQT2_CHICK Isoform 1 of Sodium channel protein OS=Gallus gallus OX=9031 GN=SCN2A PE=3 SV=3 CANONICAL=E1BQT2-1" }, "locus": { "chromosome": "7", "start_pos": 19494804, "end_pos": 19441468, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010062476.1", "url": "https://www.ensembl.org/id/ENSGALT00010062476.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038634.1", "url": "https://www.ensembl.org/id/ENSGALP00010038634.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:395945", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:395945", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8M9Q653-1", "protein_name": "Sodium channel protein", "gene_name": "scn1lab", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAAQLLVPPGPDSFRPFLPESLAAIEQRIAEEVAQRPKGERRPDDDDENGPKPNRDLEAGKPLPFIYGDVPPHMLSVPLEDLDTYYSNQKTFIVLNRGKAIFRFNATPALYILSPFNPLRRISIRVLVHSLFSFVIMCTILTNCAFMTLSNPPEWAKNVEYTFTGIYTFESLIKILARGFCVGKFTFLRDPWNWLDFSVILMAYVTEFVDLGNVSALRTFRVLRALKTISVIPGLKTIVGALIQSVKKLSDVMILTVFCLSVFALIGLQLFMGNLRQKCVKMPEVNVTDNLTDYSTELHNSTFNWTEYISDSNNYYFIPGRRDALLCGNSSDAGQCPEGFTCIKAGRNPDYGYTSFDTFSWAFLSLFRLMTQDFWENLYQQTLRAAGKPYMIFFVLVIFLGSFYLVNLILAVVAMAYDEQNQATIEEAQQKEEEFQAMLEQLKRQQEEAQVAAAAATESGEYSGRGGLSEESSSGGSRLSSKSAKERRNRRKKRKQREEEEKADQEKFHKSASEDSIRRPGFRFSIDANRLSYEKKCSTPNQSLLSIRGSLFSPRRNSRASLFSFRGRARDFGSENDFADDEHSTFEDSDSRRGSLFVPRCVERRSSTVSHCSLTAPRIMLPANGKMHCTVDCNGVVSLVGGTSVPTSPIGRLLPEGTTTESDVRKKRSGSHQPSDYLEETVARKRAMSVASILTNTMEELEESRQKCPPCWYKFANSFLIWDCSPAWLKVKEIMNMIVMDPFVDLAITICIVLNTLFMAMEHYPMTTQFSHLLSVGNLVFTGIFTAEMCLKVIALDPYYYFQEGWNIFDGIIVSLSLMELGLANVEGLSVLRSFRLLRVFKLAKSWPTLNMLIKIIGNSVGALGNLTLVLAIIVFIFAVVGMQLFGKSYRECVCKISESCELPRWHMDDFFHSFLIVFRVLCGEWIETMWDCMEVAGQSMCLIVFMMVMVIGNLVVLNLFLALLLSSFSADNLAATDDDSEMNNLQIAVGRIQKGIALVKSTLRQFLQSLFLAGSKPRSLDEEKPLDDLHSDGKENCLSNHAPVAVDLTKDYLKEGCVSPGNGVESHVKYGIEEGDYMSFIHNPSLTVTVPIAVGESDFENLNTEDFSSESSDVEGSKEKLPVDTVLSSSEGSTVDIRPPGEGAESVELEPEESLDPEACFTEGCVMRFQCCQVDVEKGKWKSWWILRKTCFIIVEHNWFESFIIFMILLSSGALAFEDIYIEQRKTIKTVLEYADKVFTYIFILEMLLKWVAYGFAKYFTNAWCWLDFLIVDVSLVSLVANALGYSELSAIKSLRTLRALRPLRALSRFEGMRVVVNALLGAIPSIMNVLLVCLIFWLIFSIMGVNLFAGKYYYCVNITNDELFPVSVVNNKSDCYALIQNNDTARWKNVKINFDNVGAGYLALLQVATFKGWMDIMYAAVDSRDLEQQPVYETNLYMYLYFVIFIIFGSFFTLNLFIGVIIDNFNQQKKKLGGQDIFMTEEQKKYYNAMKKLGSKKPQKPIPRPANKFQGLVFDLITKQAFDIIIMILICLNMVTMMVETDDQTEDMDNILYWINLVFIILFTGECVLKMISLRHYFFTIGWNVFDFVVVILSIVGMFLSEMIEKYFVSPTLFRVIRLARIGRILRLIKGAKGIRTLLFALMMSLPALFNIGLLLFLVMFIYAIFGMSNFAYVKREAGIDDMFNFETFGNSMLCLFQITTSAGWDGLLAPILNKQDPDCDSEMEHPGSFYRGNCGNPSVGIFFFVSYIIICFLIVVNMYIAVILENFSVATEESAEPLSEDDFEMFYEVWERFDPNATQFVEYNKLSDFADALDPPLRIAKPNKIQLIAMDLPMVSGDRIHCLDILFAFTLRVLGEEGEMDALRGQMEDRFMASNPSKVSYEPITTTLRRKQEEMSAVVIQRAFRRHRIRQTVKKASEAYRKQLQDGGGHIPEKEVLVIGKFQENSASDKTDMTPSSASPPSYNSVAKSEKDKYEKERREKEDKAKDARDRKK", "length": 1996 }, "evidence": [ { "id": "E1BQT2", "url": "https://omabrowser.org/oma/group/E1BQT2/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AAA9U2K0-1", "protein_name": "Sodium channel protein", "gene_name": "SCN2A", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAQSVLVPPGPDSFRFFTRESLAAIEQRIAEEKAKRPKQERKDEDDESGPKPNSDLEAGKSLPFIYGDIPPEMVSEPLEDLDPYYINKKTFIVLNKGKAISRFSATPALYILTPFNPIRKLAIKILVHSLFNVLIMCTILTNCVFMTMSNPPDWTKNVEYTFTGIYTFESLIKILARGFCLEDFTFLRDPWNWLDFTVITFAYVTEFVNLGNVSALRTFRVLRALKTISVIPGLKTIVGALIQSVKKLSDVMILTVFCLSVFALIGLQLFMGNLRNKCLQWPPDNSSFELNITSFFNNSLDGNGTTFNRTVSMFNWDEYIEDKSHFYFLEGQNDALLCGNSSDAGQCPEGYICVKAGRNPNYGYTSFDTFSWAFLSLFRLMTQDFWENLYQLTLRAAGKTYMIFFVLVIFLGSFYLINLILAVVAMAYEEQNQATLEEAEQKEAEFQQMLEQLKKQQEEAQAAAAAASAESREFSGAGGIGVFSESSSVASKLSSKSEKELKNRRKKKKQKEQSGEEEKEDGVRKSESEDSIRRKGFRFSLEGSRLTYEKRFSSPHQSLLSIRGSLFSPRRNSRASLFSFRGRAKDIGSENDFADDEHSTFEDNDSRRDSLFVPHRHGERRHSNVSQASRASRVLPILPMNGKMHSAVDCNGVVSLVGGPSALTSPAGQLLPEGTTTETEIRKRRSSSYHVSMDLLEDPTARQRAMSMASILTNTMEELEESRQKCPPCWYKFANMCLIWDCCKPWLKVKHVVNLVVMDPFVDLAITICIVLNTLFMAMEHYPMTEQFSSVLSVGNLVFTGIFTAEMFLKIIAMDPYYYFQEGWNIFDGLIVSLSLMELGLANVEGLSVLRSFRLLRVFKLAKSWPTLNMLIKIIGNSVGALGNLTLVLAIIVFIFAVVGMQLFGKSYKECVCKISNDCELPRWHMHDFFHSFLIVFRVLCGEWIETMWDCMEVAGQTMCLTVFMMVMVIGNLVVLNLFLALLLSSFSSDNLAATDDDNEMNNLQIAVGRMQKGIDFVKRKIREFIQKAFVRKQKALDEIKPLEDLNNKKDSCISNHTTIEIGKDLNYLKDGNGTTSGIGSSVEKYVVDESDYMSFINNPSLTVTVPIAVGESDFENLNTEEFSSESDMEESKEKLNATSSSEGSTVDIGAPAEGEQPEAEPEESLEPEACFTEDCVRKFKCCQISIEEGKGKLWWNLRKTCYKIVEHNWFETFIVFMILVSSGALAFEDIYIEQRKTIKTMLEYADKVFTYIFILEMLLKWVAYGFQVYFTNAWCWLDFLIVDVSLVSLTANALGYSELGAIKSLRTLRALRPLRALSRFEGMRVVVNALLGAIPSIMNVLLVCLIFWLIFSIMGVNLFAGKFYHCINYTTGEMFDVSVVNNYSECKALIDSNQTARWKNVKVNFDNVGLGYLSLLQVATFKGWMDIMYAAVDSRNVELQPKYEDNLYMYLYFVIFIIFGSFFTLNLFIGVIIDNFNQQKKKFGGQDIFMTEEQKKYYNAMKKLGSKKPQKPIPRPANKFQGMVFDFVTKQVFDISIMILICLNMVTMMVETDDQSQEMTNILYWINLVFIVLFTGECVLKLISLRYYYFTIGWNIFDFVVVILSIVGMFLAELIEKYFVSPTLFRVIRLARIGRILRLIKGAKGIRTLLFALMMSLPALFNIGLLLFLVMFIYAIFGMSNFAYVKREVGIDDMFNFETFGNSMICLFQITTSAGWDGLLAPILNSGPPDCDPEKDHPGSSVKGDCGNPSVGIFFFVSYIIISFLVVVNMYIAVILENFSVATEESAEPLSEDDFEMFYEVWEKFDPDATQFIEFSKLSDFAAALDPPLLIAKPNKVQLIAMDLPMVSGDRIHCLDILFAFTKRVLGESGEMDALRIQMEERFMASNPSKVSYEPITTTLKRKQEEVSAIVIQRAYRRYLLKQKVKKVSCIYKKDKGKEGEGTPIKEDILIDKLNENSTPEKTDMTPSTTSPPSYDSVTKPEKEKFEKDKSEKEDKGKDIRESKK", "length": 2006 }, "evidence": [ { "id": "E1BQT2", "url": "https://omabrowser.org/oma/group/E1BQT2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P04775-1", "protein_name": "Sodium channel protein type 2 subunit alpha", "gene_name": "Scn2a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MARSVLVPPGPDSFRFFTRESLAAIEQRIAEEKAKRPKQERKDEDDENGPKPNSDLEAGKSLPFIYGDIPPEMVSEPLEDLDPYYINKKTFIVLNKGKAISRFSATSALYILTPFNPIRKLAIKILVHSLFNVLIMCTILTNCVFMTMSNPPDWTKNVEYTFTGIYTFESLIKILARGFCLEDFTFLRNPWNWLDFTVITFAYVTEFVNLGNVSALRTFRVLRALKTISVIPGLKTIVGALIQSVKKLSDVMILTVFCLSVFALIGLQLFMGNLRNKCLQWPPDNSTFEINITSFFNNSLDWNGTAFNRTVNMFNWDEYIEDKSHFYFLEGQNDALLCGNSSDAGQCPEGYICVKAGRNPNYGYTSFDTFSWAFLSLFRLMTQDFWENLYQLTLRAAGKTYMIFFVLVIFLGSFYLINLILAVVAMAYEEQNQATLEEAEQKEAEFQQMLEQLKKQQEEAQAAAAAASAESRDFSGAGGIGVFSESSSVASKLSSKSEKELKNRRKKKKQKEQAGEEEKEDAVRKSASEDSIRKKGFQFSLEGSRLTYEKRFSSPHQSLLSIRGSLFSPRRNSRASLFNFKGRVKDIGSENDFADDEHSTFEDNDSRRDSLFVPHRHGERRPSNVSQASRASRGIPTLPMNGKMHSAVDCNGVVSLVGGPSALTSPVGQLLPEGTTTETEIRKRRSSSYHVSMDLLEDPSRQRAMSMASILTNTMEELEESRQKCPPCWYKFANMCLIWDCCKPWLKVKHVVNLVVMDPFVDLAITICIVLNTLFMAMEHYPMTEQFSSVLSVGNLVFTGIFTAEMFLKIIAMDPYYYFQEGWNIFDGFIVSLSLMELGLANVEGLSVLRSFRLLRVFKLAKSWPTLNMLIKIIGNSVGALGNLTLVLAIIVFIFAVVGMQLFGKSYKECVCKISNDCELPRWHMHHFFHSFLIVFRVLCGEWIETMWDCMEVAGQTMCLTVFMMVMVIGNLVVLNLFLALLLSSFSSDNLAATDDDNEMNNLQIAVGRMQKGIDFVKRKIREFIQKAFVRKQKALDEIKPLEDLNNKKDSCISNHTTIEIGKDLNYLKDGNGTTSGIGSSVEKYVVDESDYMSFINNPSLTVTVPIALGESDFENLNTEEFSSESDMEESKEKLNATSSSEGSTVDIGAPAEGEQPEAEPEESLEPEACFTEDCVRKFKCCQISIEEGKGKLWWNLRKTCYKIVEHNWFETFIVFMILLSSGALAFEDIYIEQRKTIKTMLEYADKVFTYIFILEMLLKWVAYGFQMYFTNAWCWLDFLIVDVSLVSLTANALGYSELGAIKSLRTLRALRPLRALSRFEGMRVVVNALLGAIPSIMNVLLVCLIFWLIFSIMGVNLFAGKFYHCINYTTGEMFDVSVVNNYSECQALIESNQTARWKNVKVNFDNVGLGYLSLLQVATFKGWMDIMYAAVDSRNVELQPKYEDNLYMYLYFVIFIIFGSFFTLNLFIGVIIDNFNQQKKKFGGQDIFMTEEQKKYYNAMKKLGSKKPQKPIPRPANKFQGMVFDFVTKQVFDISIMILICLNMVTMMVETDDQSQEMTNILYWINLVFIVLFTGECVLKLISLRHYYFTIGWNIFDFVVVILSIVGMFLAELIEKYFVSPTLFRVIRLARIGRILRLIKGAKGIRTLLFALMMSLPALFNIGLLLFLVMFIYAIFGMSNFAYVKREVGIDDMFNFETFGNSMICLFQITTSAGWDGLLAPILNSGPPDCDPEKDHPGSSVKGDCGNPSVGIFFFVSYIIISFLVVVNMYIAVILENFSVATEESAEPLSEDDFEMFYEVWEKFDPDATQFIEFCKLSDFAAALDPPLLIAKPNKVQLIAMDLPMVSGDRIHCLDILFAFTKRVLGESGEMDALRIQMEERFMASNPSKVSYEPITTTLKRKQEEVSAIVIQRAYRRYLLKQKVKKVSSIYKKDKGKEDEGTPIKEDIITDKLNENSTPEKTDVTPSTTSPPSYDSVTKPEKEKFEKDKSEKEDKGKDIRESKK", "length": 2005 }, "evidence": [ { "id": "E1BQT2", "url": "https://omabrowser.org/oma/group/E1BQT2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "neuronal action potential", "id": "GO:0019228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019228", "evidence": [ { "database": "UniProtKB", "id": "E1BQT2", "url": "https://www.uniprot.org/uniprotkb/E1BQT2" } ], "pmid": "" }, { "name": "sensory perception of pain", "id": "GO:0019233", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019233", "evidence": [ { "database": "UniProtKB", "id": "E1BQT2", "url": "https://www.uniprot.org/uniprotkb/E1BQT2" } ], "pmid": "" }, { "name": "membrane depolarization during action potential", "id": "GO:0086010", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0086010", "evidence": [ { "database": "UniProtKB", "id": "E1BQT2", "url": "https://www.uniprot.org/uniprotkb/E1BQT2" } ], "pmid": "" }, { "name": "sodium ion transmembrane transport", "id": "GO:0035725", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035725", "evidence": [ { "database": "UniProtKB", "id": "E1BQT2", "url": "https://www.uniprot.org/uniprotkb/E1BQT2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "axon", "id": "GO:0030424", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030424", "evidence": [ { "database": "UniProtKB", "id": "E1BQT2", "url": "https://www.uniprot.org/uniprotkb/E1BQT2" } ], "pmid": "" }, { "name": "voltage-gated sodium channel complex", "id": "GO:0001518", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001518", "evidence": [ { "database": "UniProtKB", "id": "E1BQT2", "url": "https://www.uniprot.org/uniprotkb/E1BQT2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "voltage-gated sodium channel activity", "id": "GO:0005248", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005248", "evidence": [ { "database": "UniProtKB", "id": "E1BQT2", "url": "https://www.uniprot.org/uniprotkb/E1BQT2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1056, "end_pos": 1058, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1073, "end_pos": 1075, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1137, "end_pos": 1139, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1369, "end_pos": 1371, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1383, "end_pos": 1385, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1394, "end_pos": 1396, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1779, "end_pos": 1781, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1958, "end_pos": 1960, "annotation": "n_glycosylation_sequon" }, { "start_pos": 212, "end_pos": 214, "annotation": "n_glycosylation_sequon" }, { "start_pos": 285, "end_pos": 287, "annotation": "n_glycosylation_sequon" }, { "start_pos": 297, "end_pos": 299, "annotation": "n_glycosylation_sequon" }, { "start_pos": 303, "end_pos": 305, "annotation": "n_glycosylation_sequon" }, { "start_pos": 308, "end_pos": 310, "annotation": "n_glycosylation_sequon" }, { "start_pos": 340, "end_pos": 342, "annotation": "n_glycosylation_sequon" }, { "start_pos": 604, "end_pos": 606, "annotation": "n_glycosylation_sequon" }, { "start_pos": 624, "end_pos": 626, "annotation": "n_glycosylation_sequon" }, { "start_pos": 884, "end_pos": 886, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "34963", "name": "", "equation": "Na(+)(in) = Na(+)(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "34963", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/34963" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BQT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQT2" }, { "id": "PF00520", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00520" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ion transport", "eco_id": "ECO_0000259", "start_pos": 128, "end_pos": 435, "start_aa": "His", "end_aa": "Thr", "glycosite_overlap": "" }, { "evidence": [ { "id": "E1BQT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQT2" }, { "id": "PF24609", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24609" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SCN5A-like C-terminal IQ motif", "eco_id": "ECO_0000259", "start_pos": 1899, "end_pos": 1930, "start_aa": "Thr", "end_aa": "Ser", "glycosite_overlap": "" }, { "evidence": [ { "id": "E1BQT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQT2" }, { "id": "PF06512", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06512" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Sodium ion transport-associated", "eco_id": "ECO_0000259", "start_pos": 998, "end_pos": 1204, "start_aa": "Asp", "end_aa": "Lys", "glycosite_overlap": "" }, { "evidence": [ { "id": "E1BQT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQT2" }, { "id": "PF11933", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11933" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Voltage-gated Na+ ion channel cytoplasmic", "eco_id": "ECO_0000259", "start_pos": 558, "end_pos": 710, "start_aa": "Ser", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1056, "end_pos": 1058 }, { "start_pos": 1073, "end_pos": 1075 }, { "start_pos": 1137, "end_pos": 1139 }, { "start_pos": 1369, "end_pos": 1371 }, { "start_pos": 1383, "end_pos": 1385 }, { "start_pos": 1394, "end_pos": 1396 }, { "start_pos": 1779, "end_pos": 1781 }, { "start_pos": 1958, "end_pos": 1960 }, { "start_pos": 212, "end_pos": 214 }, { "start_pos": 285, "end_pos": 287 }, { "start_pos": 297, "end_pos": 299 }, { "start_pos": 303, "end_pos": 305 }, { "start_pos": 308, "end_pos": 310 }, { "start_pos": 340, "end_pos": 342 }, { "start_pos": 604, "end_pos": 606 }, { "start_pos": 624, "end_pos": 626 }, { "start_pos": 884, "end_pos": 886 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1C8L7-1", "uniprot_ac": "E1C8L7", "uniprot_id": "E1C8L7_CHICK", "mass": { "chemical_mass": 16364.0, "monoisotopic_mass": 16364.0 }, "refseq": { "ac": "XP_001234006", "name": "leukotriene C4 synthase isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001234006" }, "gene_names": [ { "name": "LTC4SL", "type": "recommended", "evidence": [ { "id": "E1C8L7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C8L7" } ] }, { "name": "LTC4SL", "type": "synonym", "evidence": [ { "id": "XP_001234006", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001234006" } ] } ], "protein_names": [ { "name": "Leukotriene C4 synthase", "type": "recommended", "evidence": [ { "id": "E1C8L7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C8L7/entry#names_and_taxonomy" } ] }, { "name": "leukotriene C4 synthase isoform X1", "type": "synonym", "evidence": [ { "id": "XP_001234006", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001234006" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052544.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_001234006", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001234006" } ] }, { "annotation": "Catalyzes the conjugation of leukotriene A4 with reduced glutathione (GSH) to form leukotriene C4 with high specificity. Can also catalyze the transfer of a glutathionyl group from glutathione (GSH) to 13(S),14(S)-epoxy-docosahexaenoic acid to form maresin conjugate in tissue regeneration 1 (MCTR1), a bioactive lipid mediator that possess potent anti-inflammatory and proresolving actions.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YZA7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZA7#function" }, { "database": "UniProtKB", "id": "ARBA00045217", "url": "https://www.uniprot.org/uniprotkb/ARBA00045217#function" }, { "database": "UniProtKB", "id": "A0A8V0Z662", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z662#function" }, { "database": "UniProtKB", "id": "A0A8V0YYW9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYW9#function" }, { "database": "UniProtKB", "id": "A0A8V0YYX8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYX8#function" }, { "database": "UniProtKB", "id": "A0A8V0Z657", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z657#function" } ] } ], "disease": [], "snv": [], 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{ "id": "IPR001446", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001446", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023352", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023352", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050997", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050997", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:770665", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:770665", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "ARYCYFM", "url": "https://omabrowser.org/oma/group/ARYCYFM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YYW9", "url": "https://www.orthodb.org/?gene=A0A8V0YYW9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YYX8", "url": "https://www.orthodb.org/?gene=A0A8V0YYX8", "database": "OrthoDB", "categories": [ "Protein 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"-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010041019.1", "url": "https://www.ensembl.org/id/ENSGALT00010041019.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023983.1", "url": "https://www.ensembl.org/id/ENSGALP00010023983.1" } ] } }, { "isoform_ac": "A0A8V0YYX8-1", "url": "https://www.uniprot.org/uniprotkb/E1C8L7/entry#A0A8V0YYX8-1", "sequence": { "sequence": "MHQGPGTHLLNPKASFFLYGKALIVPTCSSTLSSLDVLSSCRRNRKEQKGSTSASYVRKHFCVPVIFGTSRSHCAPQLKAYFFLQVIHARRKFGISPPNISGPPEFERIFRAQVNSSEYFPIFVALLWQAGLFFHQGLAAALGLLYLYSRYCYFMGYRASSSDRLTPIYFSTGVLWVLIAAATLGLLHFFLSHYVGLNVLRLIAA", "length": 205, "header": "tr|A0A8V0YYX8-1|A0A8V0YYX8_CHICK Computationally mapped isoform of Leukotriene C4 synthase OS=Gallus gallus OX=9031 GN=LTC4SL PE=1 SV=2 CANONICAL=E1C8L7-1" }, "locus": { "chromosome": "13", "start_pos": 13172652, "end_pos": 13167821, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010041029.1", "url": "https://www.ensembl.org/id/ENSGALT00010041029.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023993.1", "url": "https://www.ensembl.org/id/ENSGALP00010023993.1" } ] } }, { "isoform_ac": "A0A8V0YZA7-1", "url": "https://www.uniprot.org/uniprotkb/E1C8L7/entry#A0A8V0YZA7-1", "sequence": { "sequence": "TKIALHVAARKALIVPTCSSTLSSLDVLSSCRRNRKEQKGSTSASYVRKHFCVPVIFGTSRSHCAPQLKAYFFLQVIHARRKFGISPPNISGPPEFERIFRAQVNSSEYFPIFVALLWQAGLFFHQGLAAALGLLYLYSRYCYFMGYRASSSDRLTPIYFSTGVLWVLIAAATLGLLHFFLSHYVGLNVLRLIAA", "length": 195, "header": "tr|A0A8V0YZA7-1|A0A8V0YZA7_CHICK Computationally mapped isoform of Leukotriene C4 synthase OS=Gallus gallus OX=9031 GN=LTC4SL PE=1 SV=1 CANONICAL=E1C8L7-1" }, "locus": { "chromosome": "13", "start_pos": 13172652, "end_pos": 13167981, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010041026.1", "url": "https://www.ensembl.org/id/ENSGALT00010041026.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023990.1", "url": "https://www.ensembl.org/id/ENSGALP00010023990.1" } ] } }, { "isoform_ac": "A0A8V0Z657-1", "url": "https://www.uniprot.org/uniprotkb/E1C8L7/entry#A0A8V0Z657-1", "sequence": { "sequence": "MGNGSALYGPLKHLLASLPMRAELRSCCTTEVASPCCPHHFQPTRQQGLDLARGAPAWEIRFYSVAMLEQIHLLAAVTVLGVLEQAYFFLQVIHARRKFGISPPNISGPPEFERIFRAQVNSSEYFPIFVALLWQAGLFFHQGLAAALGLLYLYSRYCYFMGYRASSSDRLTPIYFSTGVLWVLIAAATLGLLHFFLSHYVGLNVLRLIAA", "length": 211, "header": "tr|A0A8V0Z657-1|A0A8V0Z657_CHICK Computationally mapped isoform of Leukotriene C4 synthase OS=Gallus gallus OX=9031 GN=LTC4SL PE=1 SV=1 CANONICAL=E1C8L7-1" }, "locus": { "chromosome": "13", "start_pos": 13172652, "end_pos": 13169327, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010041013.1", "url": "https://www.ensembl.org/id/ENSGALT00010041013.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023977.1", "url": "https://www.ensembl.org/id/ENSGALP00010023977.1" } ] } }, { "isoform_ac": "A0A8V0Z662-1", "url": "https://www.uniprot.org/uniprotkb/E1C8L7/entry#A0A8V0Z662-1", "sequence": { "sequence": "MLEQIHLLAAVTVLGVLEQAYFFLQVIHARRKFGISPPNISGPPEFERIFRAQVNSSEYFPIFVALLWQAGLFFHQGLAAALGLLYLYSRYCYFMGYRASSSDRLTPIYFSTGVLWVLIAAATLGLLHFFLSHYVGLNVLQAHLTVLPIPVEPAGPQGQHSVPSCSIWLMAESSPKQGEFLENRTWRSKHFSAPASSPGTVGSVQPPTVHSQEGNF", "length": 216, "header": "tr|A0A8V0Z662-1|A0A8V0Z662_CHICK Computationally mapped isoform of Leukotriene C4 synthase OS=Gallus gallus OX=9031 GN=LTC4SL PE=1 SV=1 CANONICAL=E1C8L7-1" }, "locus": { "chromosome": "13", "start_pos": 13172932, "end_pos": 13170742, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010041018.1", "url": "https://www.ensembl.org/id/ENSGALT00010041018.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023982.1", "url": "https://www.ensembl.org/id/ENSGALP00010023982.1" } ] } }, { "isoform_ac": "E1C8L7-1", "url": "https://www.uniprot.org/uniprotkb/E1C8L7/entry#E1C8L7-1", "sequence": { "sequence": "MLEQIHLLAAVTVLGVLEQAYFFLQVIHARRKFGISPPNISGPPEFERIFRAQVNSSEYFPIFVALLWQAGLFFHQGLAAALGLLYLYSRYCYFMGYRASSSDRLTPIYFSTGVLWVLIAAATLGLLHFFLSHYVGLNVLRLIAA", "length": 145, "header": "tr|E1C8L7-1|E1C8L7_CHICK Isoform 1 of Leukotriene C4 synthase OS=Gallus gallus OX=9031 GN=LTC4SL PE=1 SV=1 CANONICAL=E1C8L7-1" }, "locus": { "chromosome": "13", "start_pos": 13172652, "end_pos": 13170742, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010041023.1", "url": "https://www.ensembl.org/id/ENSGALT00010041023.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023987.1", "url": "https://www.ensembl.org/id/ENSGALP00010023987.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "gga:770665", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:770665", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "leukotriene-C4 synthase activity", "id": "GO:0004464", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004464", "evidence": [ { "database": "UniProtKB", "id": "E1C8L7", "url": "https://www.uniprot.org/uniprotkb/E1C8L7" } ], "pmid": "" }, { "name": "enzyme activator activity", "id": "GO:0008047", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008047", "evidence": [ { "database": "UniProtKB", "id": "E1C8L7", "url": "https://www.uniprot.org/uniprotkb/E1C8L7" } ], "pmid": "" }, { "name": "transferase activity", "id": "GO:0016740", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016740", "evidence": [ { "database": "UniProtKB", "id": "E1C8L7", "url": "https://www.uniprot.org/uniprotkb/E1C8L7" } ], "pmid": "" }, { "name": "glutathione transferase activity", "id": "GO:0004364", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004364", "evidence": [ { "database": "UniProtKB", "id": "E1C8L7", "url": "https://www.uniprot.org/uniprotkb/E1C8L7" } ], "pmid": "" }, { "name": "glutathione peroxidase activity", "id": "GO:0004602", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004602", "evidence": [ { "database": "UniProtKB", "id": "E1C8L7", "url": "https://www.uniprot.org/uniprotkb/E1C8L7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "E1C8L7", "url": "https://www.uniprot.org/uniprotkb/E1C8L7" } ], "pmid": "" }, { "name": "nuclear outer membrane", "id": "GO:0005640", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005640", "evidence": [ { "database": "UniProtKB", "id": "E1C8L7", "url": "https://www.uniprot.org/uniprotkb/E1C8L7" } ], "pmid": "" }, { "name": "nuclear envelope", "id": "GO:0005635", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005635", "evidence": [ { "database": "UniProtKB", "id": "E1C8L7", "url": 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57, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "17617", "name": "", "equation": "leukotriene C4 = leukotriene A4 + glutathione", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1C8L7-1", "A0A8V0Z0H3-1", "A0A8V0Y9R9-1" ], "evidence": [ { "id": "17617", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/17617" } ] }, { "id": "53508", "name": "", "equation": "(13S,14S)-epoxy-(4Z,7Z,9E,11E,16Z,19Z)-docosahexaenoate + glutathione = (13R)-S-glutathionyl-(14S)-hydroxy-(4Z,7Z,9E,11E,16Z,19Z)-docosahexaenoate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1C8L7-1", "A0A8V0Z0H3-1" ], "evidence": [ { "id": "53508", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/53508" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A8V0Y9R9", "gene_name": 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BUS1-1", "uniprot_ac": "E1BUS1", "uniprot_id": "E1BUS1_CHICK", "mass": { "chemical_mass": 22694.0, "monoisotopic_mass": 22694.0 }, "refseq": { "ac": "XP_416411", "name": "ras-related and estrogen-regulated growth inhibitor-like protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_416411" }, "gene_names": [ { "name": "RERGL", "type": "recommended", "evidence": [ { "id": "E1BUS1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUS1" } ] }, { "name": "RERGL", "type": "synonym", "evidence": [ { "id": "XP_416411", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_416411" } ] } ], "protein_names": [ { "name": "small monomeric GTPase", "type": "recommended", "evidence": [ { "id": "E1BUS1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUS1/entry#names_and_taxonomy" } ] }, { "name": "3.6.5.2", "type": "synonym", "evidence": [ { "id": "E1BUS1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUS1/entry#names_and_taxonomy" } ] }, { "name": "ras-related and estrogen-regulated growth inhibitor-like protein", "type": "synonym", "evidence": [ { "id": "XP_416411", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_416411" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_416411", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_416411" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1BUS1", "url": "https://www.uniprot.org/uniprotkb/E1BUS1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RERGL", "url": "https://www.uniprot.org/uniprotkb/E1BUS1", "locus": { "chromosome": "1", "start_pos": 63950326, "end_pos": 63959103, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013562", "url": "https://www.ensembl.org/id/ENSGALG00010013562" } ] } } ], "crossref": [ { "id": "E1BUS1", "url": "https://alphafold.ebi.ac.uk/entry/E1BUS1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000013112", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000013112", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd04146", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04146", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "418180", "url": "https://www.ncbi.nlm.nih.gov/gene/418180", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001806", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001806", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051065", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051065", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:418180", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418180", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "LDYRCQF", "url": "https://omabrowser.org/oma/group/LDYRCQF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YSZ8", "url": "https://www.orthodb.org/?gene=A0A8V0YSZ8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1BUS1", "url": "https://www.orthodb.org/?gene=E1BUS1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45704", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45704", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00071", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00071", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_416411", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_416411", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "19669", "url": "https://www.rhea-db.org/rhea/19669", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YSZ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSZ8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YSZ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSZ8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BUS1", "url": "https://www.uniprot.org/uniprotkb/E1BUS1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BUS1-1", "url": "https://www.uniprot.org/uniprotkb/E1BUS1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSEVKLAVLGGSGAGKSALAVRFLTRRFIGEYASNAECIYTKHFCLDGRQIHLEIYDPCSQQGKLSLTDELHWADGFIIVYDISDRASFAFAKALLYRIQESHIGACKKMVESSVFLVGNKQDLCHMREVGWDEGQKLAMDNKCQFCELSAAEHYQEVVAMFTKVLRSITSNLKAKEKRRPSGSKSMAKLINNVFGKRRKSV", "length": 202, "header": "tr|E1BUS1-1|E1BUS1_CHICK Isoform 1 of small monomeric GTPase OS=Gallus gallus OX=9031 GN=RERGL PE=3 SV=2 CANONICAL=E1BUS1-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YSZ8-1", "url": "https://www.uniprot.org/uniprotkb/E1BUS1/entry#A0A8V0YSZ8-1", "sequence": { "sequence": "GGGVEYRGGLGTPSPSSPGAAGYRQGSSHLLLASFLPAALAVRFLTRRFIGEYASNAECIYTKHFCLDGRQIHLEIYDPCSQQGKLSLTDELHWADGFIIVYDISDRASFAFAKALLYRIQESHIGACKKMVESSVFLVGNKQDLCHMREVGWDEGQKLAMDNKCQFCELSAAEHYQEVVAMFTKVLRSITSNLKAKEKRRPSGSKSMAKLINNVFGKRRKSV", "length": 223, "header": "tr|A0A8V0YSZ8-1|A0A8V0YSZ8_CHICK Computationally mapped isoform of small monomeric GTPase OS=Gallus gallus OX=9031 GN=RERGL PE=3 SV=1 CANONICAL=E1BUS1-1" }, "locus": { "chromosome": "1", "start_pos": 63958821, "end_pos": 63952058, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032612.1", "url": "https://www.ensembl.org/id/ENSGALT00010032612.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019325.1", "url": "https://www.ensembl.org/id/ENSGALP00010019325.1" } ] } }, { "isoform_ac": "E1BUS1-1", "url": "https://www.uniprot.org/uniprotkb/E1BUS1/entry#E1BUS1-1", "sequence": { "sequence": "MSEVKLAVLGGSGAGKSALAVRFLTRRFIGEYASNAECIYTKHFCLDGRQIHLEIYDPCSQQGKLSLTDELHWADGFIIVYDISDRASFAFAKALLYRIQESHIGACKKMVESSVFLVGNKQDLCHMREVGWDEGQKLAMDNKCQFCELSAAEHYQEVVAMFTKVLRSITSNLKAKEKRRPSGSKSMAKLINNVFGKRRKSV", "length": 202, "header": "tr|E1BUS1-1|E1BUS1_CHICK Isoform 1 of small monomeric GTPase OS=Gallus gallus OX=9031 GN=RERGL PE=3 SV=2 CANONICAL=E1BUS1-1" }, "locus": { "chromosome": "1", "start_pos": 63958877, "end_pos": 63952058, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032614.1", "url": "https://www.ensembl.org/id/ENSGALT00010032614.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019327.1", "url": "https://www.ensembl.org/id/ENSGALP00010019327.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "gga:418180", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418180", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287B7E8-1", "protein_name": "small monomeric GTPase", "gene_name": "RERGL", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MNEVKLAVLGGEGTGKSALTVRFLTKRFIGEYASNFESIYNKYLCLEGKQLNLEIYDPCSQLQKAKFSLTSELHWADGFVIVYDISDRSSFAYAKALIYRIREPQNSHCKRAMESAVLLVGNKQDLCHVREVGWEEGQKLALDNRCQFCELSAAEQCLEVEMMFNRIIKAILTNFRLKEKRRPSGSKSMAKLINNVFGKRRKSV", "length": 204 }, "evidence": [ { "id": "E1BUS1", "url": "https://omabrowser.org/oma/group/E1BUS1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8C2M2X0-1", "protein_name": "small monomeric GTPase", "gene_name": "Rergl", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSDVKLAVLGSKSTGKSALTVRFLTKRFIGEYASNFESIYNKQLCLEGKPLNLEIYDPCSQPQKAKCPLTSELHWADGFVIVYDISDRPSFAFAKALIYRIREPPTSHCKRMVEPAVVLVGNKQDLCHMREVGWDEGQKLAIDFRCQFCELSAAEQSLEVEVMFLRLIKDILMIFKHKEKRRPSGSKSMAKLINNVFGKRRKSV", "length": 204 }, "evidence": [ { "id": "E1BUS1", "url": "https://omabrowser.org/oma/group/E1BUS1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A6QP66-1", "protein_name": "Ras-related and estrogen-regulated growth inhibitor-like protein", "gene_name": "RERGL", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MNDVKLTVLGGEGTGKSALIVRFLTKRFIGEYASNFESIYNKHLCLEGKQLNLEIYDPCSQPQKAKFSLTSELHWADGFVIVYDISDRSSFAFAKALIYRIREPQTSHCKRPVESAVLLVGNKQDLCHVREVGWEEGHKLALDNRCQFCELSAAEQSLEVEMMFIRIIRDILTNFKLKEKRRYSGSKSMAKLINNVFGKRRKSV", "length": 204 }, "evidence": [ { "id": "E1BUS1", "url": "https://omabrowser.org/oma/group/E1BUS1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "D3ZM99-1", "protein_name": "small monomeric GTPase", "gene_name": "Rergl", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGDVKLAVLGGRGTGKSALTVRFLTKRFIGEYASNFESIYNKHLCLEGKPLNLEIYDPCSQSQKAKGSLTSDLHWADGFVIVYDISNRPSFAFAKALIYRIREPPMTHCKRVMEPAVVLVGNKQDLCHMREVGWDEGQKLATDYRCQFCELSAAEQSLEIEVMFLRLIKDILMIFKHKEKRRPSGSKSMAKLINNVFGKRRKSV", "length": 204 }, "evidence": [ { "id": "E1BUS1", "url": "https://omabrowser.org/oma/group/E1BUS1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "E1BUS1", "url": "https://www.uniprot.org/uniprotkb/E1BUS1" } ], "pmid": "" }, { "name": "G protein activity", "id": "GO:0003925", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003925", "evidence": [ { "database": "UniProtKB", "id": "E1BUS1", "url": "https://www.uniprot.org/uniprotkb/E1BUS1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], 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{ "uniprot_canonical_ac": "E1BYN7-1", "uniprot_ac": "E1BYN7", "uniprot_id": "E1BYN7_CHICK", "mass": { "chemical_mass": 30707.0, "monoisotopic_mass": 30707.0 }, "refseq": { "ac": "NP_001029041", "name": "non-selective voltage-gated ion channel VDAC1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001029041" }, "gene_names": [ { "name": "VDAC1", "type": "recommended", "evidence": [ { "id": "E1BYN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BYN7" } ] }, { "name": "VDAC1", "type": "synonym", "evidence": [ { "id": "NP_001029041", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001029041" } ] } ], "protein_names": [ { "name": "Non-selective voltage-gated ion channel VDAC1", "type": "recommended", "evidence": [ { "id": "E1BYN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BYN7/entry#names_and_taxonomy" } ] }, { "name": "Voltage-dependent anion-selective channel protein 1", "type": "synonym", 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Publication Status: Online-Only", "evidence": [ { "database": "RefSeq", "id": "NP_001029041", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001029041" }, { "database": "PubMed", "id": "28592532", "url": "https://glygen.org/publication/PubMed/28592532" } ] }, { "annotation": "Results describe the expression of voltage-dependent anion channel isoforms in rat, bovine, and chicken brain mitochondria, and suggest that the nature of hexokinase binding site is not determined by the expression of a single VDAC isoform.", "evidence": [ { "database": "RefSeq", "id": "NP_001029041", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001029041" }, { "database": "PubMed", "id": "19688190", "url": "https://glygen.org/publication/PubMed/19688190" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1BYN7", "url": "https://www.uniprot.org/uniprotkb/E1BYN7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "VDAC1", "url": "https://www.uniprot.org/uniprotkb/E1BYN7", "locus": { "chromosome": "13", "start_pos": 15650729, "end_pos": 15634329, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010017393", "url": "https://www.ensembl.org/id/ENSGALG00010017393" } ] } } ], "crossref": [ { "id": "E1BYN7", "url": "https://alphafold.ebi.ac.uk/entry/E1BYN7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000006503", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000006503", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd07306", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07306", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "416320", "url": "https://www.ncbi.nlm.nih.gov/gene/416320", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "E1BYN7", "url": "https://www.ebi.ac.uk/intact/interactors/id:E1BYN7*", "database": "IntAct", "categories": [ "Other" ] }, { "id": "IPR001925", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001925", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023614", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023614", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027246", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027246", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:416320", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416320", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "KPCCSHE", "url": "https://omabrowser.org/oma/group/KPCCSHE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BYN7", "url": "https://www.orthodb.org/?gene=E1BYN7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11743", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11743", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11743:SF13", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11743:SF13", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01459", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01459", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-5205685", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5205685", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-5689880", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5689880", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-70268", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-70268", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001029041", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001029041", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "29463", "url": "https://www.rhea-db.org/rhea/29463", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "29671", "url": "https://www.rhea-db.org/rhea/29671", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "29823", "url": "https://www.rhea-db.org/rhea/29823", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "29827", "url": "https://www.rhea-db.org/rhea/29827", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "34963", "url": "https://www.rhea-db.org/rhea/34963", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "38571", "url": "https://www.rhea-db.org/rhea/38571", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "38663", "url": "https://www.rhea-db.org/rhea/38663", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "66336", "url": "https://www.rhea-db.org/rhea/66336", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "73863", "url": "https://www.rhea-db.org/rhea/73863", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "74663", "url": "https://www.rhea-db.org/rhea/74663", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "75687", "url": "https://www.rhea-db.org/rhea/75687", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "79311", "url": "https://www.rhea-db.org/rhea/79311", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YU39", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YU39", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YU39-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YU39-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z0Y0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z0Y0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z0Y0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z0Y0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BYN7", "url": "https://www.uniprot.org/uniprotkb/E1BYN7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BYN7-1", "url": "https://www.uniprot.org/uniprotkb/E1BYN7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAVPPAYADLGKSARDVFTKGYGFGLIKLDLKTKSENGLEFTSSGSANSETSKVSGSLETKYRWVEYGLMFTEKWNTDNTLGTEITLEDQLARGLKLTFDSSFSPNTGKKSAKIKTGYKREHINMGCDMDFDIAGPSIRGALVLGYEGWLAGYQMTFETAKSRVTQSNFAVGYKTDEFQLHTNVNDGTEFGGSIYQKVNEKLETAVNLAWTAGNSNTRFGIAAKYQIDPDASFSAKVNNSSLIGLGYTQTLKPGIKLTLSALLDGKNVNAGGHKLGLGLEFEA", "length": 283, "header": "tr|E1BYN7-1|E1BYN7_CHICK Isoform 1 of Non-selective voltage-gated ion channel VDAC1 OS=Gallus gallus OX=9031 GN=VDAC1 PE=1 SV=1 CANONICAL=E1BYN7-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YU39-1", "url": "https://www.uniprot.org/uniprotkb/E1BYN7/entry#A0A8V0YU39-1", "sequence": { "sequence": "MAVPPAYADLGKSARDVFTKGYGFGLIKLDLKTKSENGLEFTSSGSANSETSKVSGSLETKYRWVEYGLMFTEKWNTDNTLGTEITLEDQLARGLKLTFDSSFSPNTGKKSAKIKTGYKREHINMGCDMDFDIAGPSIRGALVLGYEGWLAGYQMTFETAKSRVTQSNFAVGYKTDEFQLHTNVNDGTEFGGSIYQKVNEKLETAVNLAWTAGNSNTRFGIAAKYQIDPDASFSAKVNNSSLIGLGYTQTLKPADIVSFVGWQECQCRWSQAWSRIGI", "length": 278, "header": "tr|A0A8V0YU39-1|A0A8V0YU39_CHICK Computationally mapped isoform of Non-selective voltage-gated ion channel VDAC1 OS=Gallus gallus OX=9031 GN=VDAC1 PE=1 SV=1 CANONICAL=E1BYN7-1" }, "locus": { "chromosome": "13", "start_pos": 15649849, "end_pos": 15641835, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010041972.1", "url": "https://www.ensembl.org/id/ENSGALT00010041972.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024566.1", "url": "https://www.ensembl.org/id/ENSGALP00010024566.1" } ] } }, { "isoform_ac": "A0A8V0Z0Y0-1", "url": "https://www.uniprot.org/uniprotkb/E1BYN7/entry#A0A8V0Z0Y0-1", "sequence": { "sequence": "MQTSPVLAASLLGYKNPKMAVPPAYADLGKSARDVFTKGYGFGLIKLDLKTKSENGLEFTSSGSANSETSKVSGSLETKYRWVEYGLMFTEKWNTDNTLGTEITLEDQLARGLKLTFDSSFSPNTGKKSAKIKTGYKREHINMGCDMDFDIAGPSIRGALVLGYEGWLAGYQMTFETAKSRVTQSNFAVGYKTDEFQLHTNVNDGTEFGGSIYQKVNEKLETAVNLAWTAGNSNTRFGIAAKYQIDPDASFSAKVNNSSLIGLGYTQTLKPGIKLTLSALLDGKNVNAGGHKLGLGLEFEA", "length": 301, "header": "tr|A0A8V0Z0Y0-1|A0A8V0Z0Y0_CHICK Computationally mapped isoform of Non-selective voltage-gated ion channel VDAC1 OS=Gallus gallus OX=9031 GN=VDAC1 PE=1 SV=1 CANONICAL=E1BYN7-1" }, "locus": { "chromosome": "13", "start_pos": 15649856, "end_pos": 15634592, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010041977.1", "url": "https://www.ensembl.org/id/ENSGALT00010041977.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024570.1", "url": "https://www.ensembl.org/id/ENSGALP00010024570.1" } ] } }, { "isoform_ac": "E1BYN7-1", "url": "https://www.uniprot.org/uniprotkb/E1BYN7/entry#E1BYN7-1", "sequence": { "sequence": "MAVPPAYADLGKSARDVFTKGYGFGLIKLDLKTKSENGLEFTSSGSANSETSKVSGSLETKYRWVEYGLMFTEKWNTDNTLGTEITLEDQLARGLKLTFDSSFSPNTGKKSAKIKTGYKREHINMGCDMDFDIAGPSIRGALVLGYEGWLAGYQMTFETAKSRVTQSNFAVGYKTDEFQLHTNVNDGTEFGGSIYQKVNEKLETAVNLAWTAGNSNTRFGIAAKYQIDPDASFSAKVNNSSLIGLGYTQTLKPGIKLTLSALLDGKNVNAGGHKLGLGLEFEA", "length": 283, "header": "tr|E1BYN7-1|E1BYN7_CHICK Isoform 1 of Non-selective voltage-gated ion channel VDAC1 OS=Gallus gallus OX=9031 GN=VDAC1 PE=1 SV=1 CANONICAL=E1BYN7-1" }, "locus": { "chromosome": "13", "start_pos": 15649856, "end_pos": 15641835, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010041967.1", "url": "https://www.ensembl.org/id/ENSGALT00010041967.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024563.1", "url": "https://www.ensembl.org/id/ENSGALP00010024563.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Relationship between expression of voltage-dependent anion channel (VDAC) isoforms and type of hexokinase binding sites on brain mitochondria.", "journal": "Journal of molecular neuroscience : MN", "date": "2010-05", "authors": "Poleti Mirele Daiana, Tesch Andrea Cristina, Crepaldi Carla Rossini, Souza Gustavo Henrique Martins Ferreira, Eberlin Marcos Nogueira, de Cerqueira C\u00e9sar Marcelo", "evidence": [ { "database": "RefSeq", "id": "NP_001029041", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001029041" } ], "reference": [ { "type": "PubMed", "id": "19688190", "url": "https://glygen.org/publication/PubMed/19688190" } ] }, { "title": "Voltage-Dependent Anion Channel 1 Interacts with Ribonucleoprotein Complexes To Enhance Infectious Bursal Disease Virus Polymerase Activity.", "journal": "Journal of virology", "date": "2017-08-15", "authors": "Han Chunyan, Zeng Xiangwei, Yao Shuai, Gao Li, Zhang Lizhou, Qi Xiaole, Duan Yulu, Yang Bo, Gao Yulong, Liu Changjun, Zhang Yanping, Wang Yongqiang, Wang Xiaomei", "evidence": [ { "database": "RefSeq", "id": "NP_001029041", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001029041" } ], "reference": [ { "type": "PubMed", "id": "28592532", "url": "https://glygen.org/publication/PubMed/28592532" } ] } ], "pathway": [ { "id": "gga:416320", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416320", "resource": "KEGG Pathway" }, { "id": "R-GGA-5205685", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5205685", "resource": "Reactome", "description": "PINK1-PRKN Mediated Mitophagy" }, { "id": "R-GGA-5689880", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5689880", "resource": "Reactome", "description": "Ub-specific processing proteases" }, { "id": "R-GGA-70268", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-70268", "resource": "Reactome", "description": "Pyruvate metabolism" } ], "orthologs": [ { "uniprot_canonical_ac": "P04840-1", "protein_name": "Non-selective voltage-gated ion channel 1", "gene_name": "POR1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSPPVYSDISRNINDLLNKDFYHATPAAFDVQTTTANGIKFSLKAKQPVKDGPLSTNVEAKLNDKQTGLGLTQGWSNTNNLQTKLEFANLTPGLKNELITSLTPGVAKSAVLNTTFTQPFFTARGAFDLCLKSPTFVGDLTMAHEGIVGGAEFGYDISAGSISRYAMALSYFAKDYSLGATLNNEQITTVDFFQNVNAFLQVGAKATMNCKLPNSNVNIEFATRYLPDASSQVKAKVSDSGIVTLAYKQLLRPGVTLGVGSSFDALKLSEPVHKLGWSLSFDA", "length": 283 }, "evidence": [ { "id": "E1BYN7", "url": "https://omabrowser.org/oma/group/E1BYN7/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P21796-1", "protein_name": "Non-selective voltage-gated ion channel VDAC1", "gene_name": "VDAC1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAVPPTYADLGKSARDVFTKGYGFGLIKLDLKTKSENGLEFTSSGSANTETTKVTGSLETKYRWTEYGLTFTEKWNTDNTLGTEITVEDQLARGLKLTFDSSFSPNTGKKNAKIKTGYKREHINLGCDMDFDIAGPSIRGALVLGYEGWLAGYQMNFETAKSRVTQSNFAVGYKTDEFQLHTNVNDGTEFGGSIYQKVNKKLETAVNLAWTAGNSNTRFGIAAKYQIDPDACFSAKVNNSSLIGLGYTQTLKPGIKLTLSALLDGKNVNAGGHKLGLGLEFQA", "length": 283 }, "evidence": [ { "id": "E1BYN7", "url": "https://omabrowser.org/oma/group/E1BYN7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P45879-1", "protein_name": "Non-selective voltage-gated ion channel VDAC1", "gene_name": "VDAC1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAVPPTYADLGKSARDVFTKGYGFGLIKLDLKTKSENGLEFTSSGSANTETTKVTGSLETKYRWTEYGLTFTEKWNTDNTLGTEITVEDQLARGLKLTFDSSFSPNTGKKNAKIKTGYKREHINLGCDVDFDIAGPSIRGALVLGYEGWLAGYQMNFETAKSRVTQSNFAVGYKTDEFQLHTNVNDGTEFGGSIYQKVNKKLETAVNLAWTAGNSNTRFGIAAKYQIDPDACFSAKVNNSSLIGLGYTQTLKPGIKLTLSALLDGKNVNAGGHKLGLGLEFQA", "length": 283 }, "evidence": [ { "id": "E1BYN7", "url": "https://omabrowser.org/oma/group/E1BYN7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q60932-1", "protein_name": "Non-selective voltage-gated ion channel VDAC1", "gene_name": "Vdac1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MCSFFLVLLLWQNMAVPPTYADLGKSARDVFTKGYGFGLIKLDLKTKSENGLEFTSSGSANTETTKVNGSLETKYRWTEYGLTFTEKWNTDNTLGTEITVEDQLARGLKLTFDSSFSPNTGKKNAKIKTGYKREHINLGCDVDFDIAGPSIRGALVLGYEGWLAGYQMNFETSKSRVTQSNFAVGYKTDEFQLHTNVNDGTEFGGSIYQKVNKKLETAVNLAWTAGNSNTRFGIAAKYQVDPDACFSAKVNNSSLIGLGYTQTLKPGIKLTLSALLDGKNVNAGGHKLGLGLEFQA", "length": 296 }, "evidence": [ { "id": "E1BYN7", "url": "https://omabrowser.org/oma/group/E1BYN7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9MZ16-1", "protein_name": "Non-selective voltage-gated ion channel VDAC1", "gene_name": "VDAC1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAVPPTYADLGKSARDVFTKGYGFGLIKLDLKTKSENGLEFTSSGSANTETTKVTGSLETKYRWTEYGLTFTEKWNTDNTLGTEITVEDQLARGLKLTFDSSFSPNTGKKNAKIKTGYKREHVNLGCDVDFDIAGPSIRGALVLGYEGWLAGYQMNFETAKSRVTQSNFAVGYKTDEFQLHTNVNDGTEFGGSIYQKVNKKLETAVNLAWTAGNSNTRFGIAAKYQIDPDACFSAKVNNSSLIGLGYTQTLKPGIKLTLSALLDGKNVNAGGHKLGLGLEFQA", "length": 283 }, "evidence": [ { "id": "E1BYN7", "url": "https://omabrowser.org/oma/group/E1BYN7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q9Z2L0-1", "protein_name": "Non-selective voltage-gated ion channel VDAC1", "gene_name": "Vdac1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAVPPTYADLGKSARDVFTKGYGFGLIKLDLKTKSENGLEFTSSGSANTETTKVNGSLETKYRWTEYGLTFTEKWNTDNTLGTEITVEDQLARGLKLTFDSSFSPNTGKKNAKIKTGYKREHINLGCDVDFDIAGPSIRGALVLGYEGWLAGYQMNFETSKSRVTQSNFAVGYKTDEFQLHTNVNDGTEFGGSIYQKVNKKLETAVNLAWTAGNSNTRFGIAAKYQVDPDACFSAKVNNSSLIGLGYTQTLKPGIKLTLSALLDGKNVNAGGHKLGLGLEFQA", "length": 283 }, "evidence": [ { "id": "E1BYN7", "url": "https://omabrowser.org/oma/group/E1BYN7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 10, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "E1BYN7", "url": "https://www.uniprot.org/uniprotkb/E1BYN7" } ], "pmid": "" }, { "name": "porin activity", "id": "GO:0015288", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015288", "evidence": [ { "database": "UniProtKB", "id": "E1BYN7", "url": "https://www.uniprot.org/uniprotkb/E1BYN7" } ], "pmid": "" }, { "name": "voltage-gated monoatomic anion channel activity", "id": "GO:0008308", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008308", "evidence": [ { "database": "UniProtKB", "id": "E1BYN7", "url": "https://www.uniprot.org/uniprotkb/E1BYN7" } ], "pmid": "" }, { "name": "oxysterol binding", "id": "GO:0008142", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008142", "evidence": [ { "database": "UniProtKB", "id": "E1BYN7", "url": "https://www.uniprot.org/uniprotkb/E1BYN7" } ], "pmid": "" }, { "name": "protein kinase binding", "id": "GO:0019901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019901", "evidence": [ { "database": "UniProtKB", "id": "E1BYN7", "url": "https://www.uniprot.org/uniprotkb/E1BYN7" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "E1BYN7", "url": "https://www.uniprot.org/uniprotkb/E1BYN7" } ], "pmid": "" }, { "name": "transmembrane transporter binding", "id": "GO:0044325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044325", "evidence": [ { "database": "UniProtKB", "id": "E1BYN7", "url": "https://www.uniprot.org/uniprotkb/E1BYN7" } ], "pmid": "" }, { "name": "cholesterol binding", "id": "GO:0015485", "url": 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"GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "E1BYN7", "url": "https://www.uniprot.org/uniprotkb/E1BYN7" } ], "pmid": "" }, { "name": "membrane raft", "id": "GO:0045121", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045121", "evidence": [ { "database": "UniProtKB", "id": "E1BYN7", "url": "https://www.uniprot.org/uniprotkb/E1BYN7" } ], "pmid": "" }, { "name": "pore complex", "id": "GO:0046930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046930", "evidence": [ { "database": "UniProtKB", "id": "E1BYN7", "url": "https://www.uniprot.org/uniprotkb/E1BYN7" } ], "pmid": "" }, { "name": "mitochondrial nucleoid", "id": "GO:0042645", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042645", "evidence": [ { "database": "UniProtKB", "id": "E1BYN7", "url": "https://www.uniprot.org/uniprotkb/E1BYN7" } ], "pmid": "" }, { "name": "mitochondrial permeability transition pore complex", "id": "GO:0005757", "url": 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"MGLLSILRKLKSTPDQEVRILLLGLDNAGKTTLLKQLASEDISHITPTQGFNIKSVQSQGFKLNVWDIGGQRKIRPYWRNYFENTDILIYVIDSADRKRFEETGQELAELLDEEKLGGVPVLIFANKQDLLTAAPASEIAEGLNLHTIRDRVWQIQSCSALSGEGVQDGMNWVCKNVNAKKK", "length": 182, "header": "tr|F1N9A3-1|F1N9A3_CHICK Isoform 1 of ADP-ribosylation factor-like protein 3 OS=Gallus gallus OX=9031 GN=ARL3 PE=1 SV=3 CANONICAL=F1N9A3-1" }, "locus": { "chromosome": "6", "start_pos": 24116324, "end_pos": 24091841, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010045187.1", "url": "https://www.ensembl.org/id/ENSGALT00010045187.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026985.1", "url": "https://www.ensembl.org/id/ENSGALP00010026985.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": 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pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052554.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_001233575", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001233575" } ] }, { "annotation": "Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. 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SAMEA103992290, SAMEA103992323 [ECO:0006172] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: inferred from homology ##RefSeq-Attributes-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000252.1. 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{ "name": "FHIT", "url": "https://www.uniprot.org/uniprotkb/F1NA30", "locus": { "chromosome": "12", "start_pos": 12342540, "end_pos": 12854426, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021016", "url": "https://www.ensembl.org/id/ENSGALG00010021016" } ] } } ], "crossref": [ { "id": "F1NA30", "url": "https://alphafold.ebi.ac.uk/entry/F1NA30", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000007172", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000007172", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd01275", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01275", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "416071", "url": "https://www.ncbi.nlm.nih.gov/gene/416071", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011146", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011146", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019808", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019808", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036265", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036265", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039383", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039383", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052677", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052677", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:416071", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416071", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DAIYGMM", "url": "https://omabrowser.org/oma/group/DAIYGMM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z9S7", "url": "https://www.orthodb.org/?gene=A0A8V0Z9S7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZFI3", "url": "https://www.orthodb.org/?gene=A0A8V0ZFI3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZFI8", "url": "https://www.orthodb.org/?gene=A0A8V0ZFI8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZFK2", "url": "https://www.orthodb.org/?gene=A0A8V0ZFK2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZGS3", "url": "https://www.orthodb.org/?gene=A0A8V0ZGS3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZMY4", "url": "https://www.orthodb.org/?gene=A0A8V0ZMY4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NA30", "url": "https://www.orthodb.org/?gene=F1NA30", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46981", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46981", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46981:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46981:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01230", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01230", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001264731", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264731", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "13893", "url": "https://www.rhea-db.org/rhea/13893", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "17041", "url": "https://www.rhea-db.org/rhea/17041", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "19197", "url": "https://www.rhea-db.org/rhea/19197", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "67916", "url": "https://www.rhea-db.org/rhea/67916", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0Z9S7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9S7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z9S7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9S7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZFI3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFI3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZFI3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFI3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZFI8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFI8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZFI8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFI8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZFK2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFK2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZFK2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFK2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZGS3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGS3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZGS3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGS3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZMY4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMY4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZMY4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMY4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NA30", "url": "https://www.uniprot.org/uniprotkb/F1NA30", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NA30-1", "url": "https://www.uniprot.org/uniprotkb/F1NA30-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLRFGQNLIKPSVVFLKTELSFALVNRKPVVPGHVLVCPVRPVERFRDLCPEEVADLFRTAQRVGNAVEKHFCATSLTIAIQDGPEAGQTVKHVHVHVLPRRSGDFSRNDDVYKELQDHDKEDSPDKWRTEEEMAAEAAVLKKYFQEN", "length": 148, "header": "tr|F1NA30-1|F1NA30_CHICK Isoform 1 of Bis(5'-adenosyl)-triphosphatase OS=Gallus gallus OX=9031 GN=FHIT PE=4 SV=4 CANONICAL=F1NA30-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z9S7-1", "url": "https://www.uniprot.org/uniprotkb/F1NA30/entry#A0A8V0Z9S7-1", "sequence": { "sequence": "MRARRRSALQLQLSDWFKHISHIPTQRTTSIMLRFGQNLIKPSVVFLKTELSFALVNRKPVVPGHVLVCPVRPVERFRDLCPEEVADLFRTAQRVGNAVEKHFCATSLTIAIQDGPEAGQTVKHVHVHVLPRRSGDFSRNDDVYKELQDHDKEDSPDKWRTEEEMAAEAAVLKKYFQEN", "length": 179, "header": "tr|A0A8V0Z9S7-1|A0A8V0Z9S7_CHICK Computationally mapped isoform of Bis(5'-adenosyl)-triphosphatase OS=Gallus gallus OX=9031 GN=FHIT PE=4 SV=1 CANONICAL=F1NA30-1" }, "locus": { "chromosome": "12", "start_pos": 12854325, "end_pos": 12349780, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050841.1", "url": "https://www.ensembl.org/id/ENSGALT00010050841.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030032.1", "url": "https://www.ensembl.org/id/ENSGALP00010030032.1" } ] } }, { "isoform_ac": "A0A8V0ZFI3-1", "url": "https://www.uniprot.org/uniprotkb/F1NA30/entry#A0A8V0ZFI3-1", "sequence": { "sequence": "TSSAPETGSWHISALGQHRISCRFPSDVLVCPVRPVERFRDLCPEEVADLFRTAQRVGNAVEKHFCATSLTIAIQDGPEAGQTVKHVHVHVLPRRSGDFSRNDDVYKELQDHDKEDSPDKWRTEEEMAAEAAVLKKYFQEN", "length": 141, "header": "tr|A0A8V0ZFI3-1|A0A8V0ZFI3_CHICK Computationally mapped isoform of Bis(5'-adenosyl)-triphosphatase OS=Gallus gallus OX=9031 GN=FHIT PE=4 SV=1 CANONICAL=F1NA30-1" }, "locus": { "chromosome": "12", "start_pos": 12544384, "end_pos": 12349780, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050829.1", "url": "https://www.ensembl.org/id/ENSGALT00010050829.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030019.1", "url": "https://www.ensembl.org/id/ENSGALP00010030019.1" } ] } }, { "isoform_ac": "A0A8V0ZFI8-1", "url": "https://www.uniprot.org/uniprotkb/F1NA30/entry#A0A8V0ZFI8-1", "sequence": { "sequence": "GPGTEGRASLEPEPRLLPGKLYCITIEPLDQLDVLVCPVRPVERFRDLCPEEVADLFRTAQRVGNAVEKHFCATSLTIAIQDGPEAGQTVKHVHVHVLPRRSGDFSRNDDVYKELQDHDKEDSPDKWRTEEEMAAEAAVLKKYFQEN", "length": 147, "header": "tr|A0A8V0ZFI8-1|A0A8V0ZFI8_CHICK Computationally mapped isoform of Bis(5'-adenosyl)-triphosphatase OS=Gallus gallus OX=9031 GN=FHIT PE=4 SV=1 CANONICAL=F1NA30-1" }, "locus": { "chromosome": "12", "start_pos": 12621253, "end_pos": 12349780, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050833.1", "url": "https://www.ensembl.org/id/ENSGALT00010050833.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030024.1", "url": "https://www.ensembl.org/id/ENSGALP00010030024.1" } ] } }, { "isoform_ac": "A0A8V0ZFK2-1", "url": "https://www.uniprot.org/uniprotkb/F1NA30/entry#A0A8V0ZFK2-1", "sequence": { "sequence": "MRARRRSTQRTTSIMLRFGQNLIKPSVVFLKTELSFALVNRKPVVPGHVLVCPVRPVERFRDLCPEEVADLFRTAQRVGNAVEKHFCATSLTIAIQDGPEAGQTVKHVHVHVLPRRSGDFSRNDDVYKELQDHDKEDSPDKWRTEEEMAAEAAVLKKYFQEN", "length": 162, "header": "tr|A0A8V0ZFK2-1|A0A8V0ZFK2_CHICK Computationally mapped isoform of Bis(5'-adenosyl)-triphosphatase OS=Gallus gallus OX=9031 GN=FHIT PE=4 SV=1 CANONICAL=F1NA30-1" }, "locus": { "chromosome": "12", "start_pos": 12854325, "end_pos": 12349780, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050848.1", "url": "https://www.ensembl.org/id/ENSGALT00010050848.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030039.1", "url": "https://www.ensembl.org/id/ENSGALP00010030039.1" } ] } }, { "isoform_ac": "A0A8V0ZGS3-1", "url": "https://www.uniprot.org/uniprotkb/F1NA30/entry#A0A8V0ZGS3-1", "sequence": { "sequence": "MADCLLFKFLQFSQQLKTQRTTSIMLRFGQNLIKPSVVFLKTELSFALVNRKPVVPGHVLVCPVRPVERFRDLCPEEVADLFRTAQRVGNAVEKHFCATSLTIAIQDGPEAGQTVKHVHVHVLPRRSGDFSRNDDVYKELQDHDKEDSPDKWRTEEEMAAEAAVLKKYFQEN", "length": 172, "header": "tr|A0A8V0ZGS3-1|A0A8V0ZGS3_CHICK Computationally mapped isoform of Bis(5'-adenosyl)-triphosphatase OS=Gallus gallus OX=9031 GN=FHIT PE=4 SV=1 CANONICAL=F1NA30-1" }, "locus": { "chromosome": "12", "start_pos": 12786463, "end_pos": 12349780, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050835.1", "url": "https://www.ensembl.org/id/ENSGALT00010050835.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030026.1", "url": "https://www.ensembl.org/id/ENSGALP00010030026.1" } ] } }, { "isoform_ac": "A0A8V0ZMY4-1", "url": "https://www.uniprot.org/uniprotkb/F1NA30/entry#A0A8V0ZMY4-1", "sequence": { "sequence": "MRARRRSMASFMSLMFLGKLSVTQRTTSIMLRFGQNLIKPSVVFLKTELSFALVNRKPVVPGHVLVCPVRPVERFRDLCPEEVADLFRTAQRVGNAVEKHFCATSLTIAIQDGPEAGQTVKHVHVHVLPRRSGDFSRNDDVYKELQDHDKEDSPDKWRTEEEMAAEAAVLKKYFQEN", "length": 177, "header": "tr|A0A8V0ZMY4-1|A0A8V0ZMY4_CHICK Computationally mapped isoform of Bis(5'-adenosyl)-triphosphatase OS=Gallus gallus OX=9031 GN=FHIT PE=4 SV=1 CANONICAL=F1NA30-1" }, "locus": { "chromosome": "12", "start_pos": 12854325, "end_pos": 12349780, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050842.1", "url": "https://www.ensembl.org/id/ENSGALT00010050842.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030033.1", "url": "https://www.ensembl.org/id/ENSGALP00010030033.1" } ] } }, { "isoform_ac": "F1NA30-1", "url": "https://www.uniprot.org/uniprotkb/F1NA30/entry#F1NA30-1", "sequence": { "sequence": "MLRFGQNLIKPSVVFLKTELSFALVNRKPVVPGHVLVCPVRPVERFRDLCPEEVADLFRTAQRVGNAVEKHFCATSLTIAIQDGPEAGQTVKHVHVHVLPRRSGDFSRNDDVYKELQDHDKEDSPDKWRTEEEMAAEAAVLKKYFQEN", "length": 148, "header": "tr|F1NA30-1|F1NA30_CHICK Isoform 1 of Bis(5'-adenosyl)-triphosphatase OS=Gallus gallus OX=9031 GN=FHIT PE=4 SV=4 CANONICAL=F1NA30-1" }, "locus": { "chromosome": "12", "start_pos": 12723089, "end_pos": 12349780, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050845.1", "url": "https://www.ensembl.org/id/ENSGALT00010050845.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030036.1", "url": "https://www.ensembl.org/id/ENSGALP00010030036.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "Comparative metabolic pathway analysis with special reference to nucleotide metabolism-related genes in chicken primordial germ cells.", "journal": "Theriogenology", "date": "2013-01-01", "authors": "Rengaraj Deivendran, Lee Bo Ram, Jang Hyun-Jun, Kim Young Min, Han Jae Yong", "evidence": [ { "database": "RefSeq", "id": "NP_001264731", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264731" } ], "reference": [ { "type": "PubMed", "id": "23102846", "url": "https://glygen.org/publication/PubMed/23102846" } ] } ], "pathway": [ { "id": "gga:416071", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416071", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "F4KEV7-1", "protein_name": "Bifunctional bis(5'-adenosyl)-triphosphatase/adenylylsulfatase FHIT", "gene_name": "FHIT", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MLNLQVTGKTILSSIRCQRKMSSTCSSYAFGPYKIDPREVFYATPLSYAMVNLRPLLPAHVLVCPRRLVPRFTDLTADETSDLWLTAQKVGSKLETFHNASSLTLAIQDGPQAGQTVPHVHIHILPRKGGDFEKNDEIYDALDEKEKELKQKLDLDKDRVDRSIQEMADEASQYRSLFDC", "length": 180 }, "evidence": [ { "id": "F1NA30", "url": "https://omabrowser.org/oma/group/F1NA30/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "O89106-1", "protein_name": "Bis(5'-adenosyl)-triphosphatase", "gene_name": "Fhit", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSFRFGQHLIKPSVVFLKTELSFALVNRKPVVPGHVLVCPLRPVERFRDLHPDEVADLFQVTQRVGTVVEKHFQGTSITFSMQDGPEAGQTVKHVHVHVLPRKAGDFPRNDNIYDELQKHDREEEDSPAFWRSEKEMAAEAEALRVYFQA", "length": 150 }, "evidence": [ { "id": "F1NA30", "url": "https://omabrowser.org/oma/group/F1NA30/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P49789-1", "protein_name": "Bis(5'-adenosyl)-triphosphatase", "gene_name": "FHIT", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSFRFGQHLIKPSVVFLKTELSFALVNRKPVVPGHVLVCPLRPVERFHDLRPDEVADLFQTTQRVGTVVEKHFHGTSLTFSMQDGPEAGQTVKHVHVHVLPRKAGDFHRNDSIYEELQKHDKEDFPASWRSEEEMAAEAAALRVYFQ", "length": 147 }, "evidence": [ { "id": "F1NA30", "url": "https://omabrowser.org/oma/group/F1NA30/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q1KZG4-1", "protein_name": "Bis(5'-adenosyl)-triphosphatase", "gene_name": "FHIT", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSFRFGQHLIKPSVVFLKTELSFALVNRKPVVPGHVLVCPLRPVERFRDMSPEEVADLFQAAQRVGTVVEKHFQGTSLTFSMQDGPEAGQTVKHVHVHILPRKAGDFHRNDSIYDALEKHDREDKDSPALWRSEEEMAAEAAALRVYFQ", "length": 149 }, "evidence": [ { "id": "F1NA30", "url": "https://omabrowser.org/oma/group/F1NA30/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q86KK2-1", "protein_name": "Bis(5'-adenosyl)-triphosphatase", "gene_name": "fhit", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MTTTYFGPWLIRQSEIFFTTELSFALVNLKPVLPGHVLVCPKRIVPRVKDLTKEEFTDLWLSAQRISSVVEEHFNGDGITFAIQDGKNAGQTVEHVHIHIIPRKKFDFENNDQIYNEIEKEREPRSYEEMEKESSELRPLFEENKNKTF", "length": 149 }, "evidence": [ { "id": "F1NA30", "url": "https://omabrowser.org/oma/group/F1NA30/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q9JIX3-1", "protein_name": "Bis(5'-adenosyl)-triphosphatase", "gene_name": "Fhit", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSFKFGQHLIKPSVVFLKTELSFALVNRKPVVPGHVLMCPLRPVERFRDLRPDEVADLFQVTQRVGTVVEKHFQGTSITFSMQDGPEAGQTVKHVHVHILPRKSGDFRRNDNIYDELQKHDREEEDSPAFWRSEEEMAAEAEVLRAYFQA", "length": 150 }, "evidence": [ { "id": "F1NA30", "url": "https://omabrowser.org/oma/group/F1NA30/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "diadenosine triphosphate catabolic process", "id": "GO:0015964", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015964", "evidence": [ { "database": "UniProtKB", "id": "F1NA30", "url": "https://www.uniprot.org/uniprotkb/F1NA30" } ], "pmid": "" }, { "name": "intrinsic apoptotic signaling pathway by p53 class mediator", "id": "GO:0072332", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072332", "evidence": [ { "database": "UniProtKB", "id": "F1NA30", "url": "https://www.uniprot.org/uniprotkb/F1NA30" } ], "pmid": "" }, { "name": "negative regulation of proteasomal ubiquitin-dependent protein catabolic process", "id": "GO:0032435", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032435", "evidence": [ { "database": "UniProtKB", "id": "F1NA30", "url": "https://www.uniprot.org/uniprotkb/F1NA30" } ], "pmid": "" }, { "name": "purine nucleotide metabolic process", "id": "GO:0006163", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006163", "evidence": [ { "database": "UniProtKB", "id": "F1NA30", "url": "https://www.uniprot.org/uniprotkb/F1NA30" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1NA30", "url": "https://www.uniprot.org/uniprotkb/F1NA30" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1NA30", "url": "https://www.uniprot.org/uniprotkb/F1NA30" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F1NA30", "url": "https://www.uniprot.org/uniprotkb/F1NA30" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F1NA30", "url": "https://www.uniprot.org/uniprotkb/F1NA30" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 7, "go_terms": [ { "name": "identical protein binding", "id": "GO:0042802", "url": 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REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052553.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015152979", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015152979" } ] }, { "annotation": "May play a role in mRNA splicing.", "evidence": [ { "database": "UniProtKB", "id": "E1BYM5", "url": "https://www.uniprot.org/uniprotkb/E1BYM5#function" }, { "database": "UniProtKB", "id": "ARBA00003632", "url": "https://www.uniprot.org/uniprotkb/ARBA00003632#function" }, { "database": "UniProtKB", "id": "A0A8V0ZAW6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAW6#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1BYM5", "url": "https://www.uniprot.org/uniprotkb/E1BYM5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": 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"url": "https://www.uniprot.org/uniprotkb/E1BYM5/entry#A0A8V0ZAW6-1", "sequence": { "sequence": "MSPRPSPEGRGREGAAGPSSSSSSSSSRSPPPLLRRSPRSAHRRRSRSASRDRERRRRERTRSRDRDRRRTRSRSPHRRRSRSPRRHRSSSSSPLRLKERRDEEKKESKDTKGKERQITEEDLQGKTEEEIEMMKMMGFASFDTTKGKKVDGAANAYAINVSQKRKYRQYMNRKGGFNRPLDFIA", "length": 185, "header": "tr|A0A8V0ZAW6-1|A0A8V0ZAW6_CHICK Computationally mapped isoform of U4/U6.U5 small nuclear ribonucleoprotein 27 kDa protein OS=Gallus gallus OX=9031 GN=SNRNP27 PE=1 SV=1 CANONICAL=E1BYM5-1" }, "locus": { "chromosome": "22", "start_pos": 3397524, "end_pos": 3396231, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010046686.1", "url": "https://www.ensembl.org/id/ENSGALT00010046686.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027804.1", "url": "https://www.ensembl.org/id/ENSGALP00010027804.1" } ] } }, { "isoform_ac": "E1BYM5-1", "url": "https://www.uniprot.org/uniprotkb/E1BYM5/entry#E1BYM5-1", "sequence": { "sequence": "MGRSRSRSPPRRDRRRSRSASRDRERRRRERTRSRDRDRRRTRSRSPHRRRSRSPRRHRSSSSSPLRLKERRDEEKKESKDTKGKERQITEEDLQGKTEEEIEMMKMMGFASFDTTKGKKVDGAANAYAINVSQKRKYRQYMNRKGGFNRPLDFIA", "length": 156, "header": "tr|E1BYM5-1|E1BYM5_CHICK Isoform 1 of U4/U6.U5 small nuclear ribonucleoprotein 27 kDa protein OS=Gallus gallus OX=9031 GN=SNRNP27 PE=1 SV=4 CANONICAL=E1BYM5-1" }, "locus": { "chromosome": "22", "start_pos": 3397524, "end_pos": 3396051, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010046689.1", "url": "https://www.ensembl.org/id/ENSGALT00010046689.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027805.1", "url": "https://www.ensembl.org/id/ENSGALP00010027805.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:771295", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:771295", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "I3LA25-1", "protein_name": "U4/U6.U5 small nuclear ribonucleoprotein 27 kDa protein", "gene_name": "SNRNP27", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGRSRSRSPRRERRRSRSTSRERERRRRERSRSRERDRRRSRSRSPHRRRSRSPRRHRSTSPSPSRLKERRDEEKKETKEIKSKERQITEEDLEGKTEEEIEMMKLMGFASFDSTKGKKVDGSVNAYAINVSQKRKYRQYMNRKGGFNRPLDFIA", "length": 155 }, "evidence": [ { "id": "E1BYM5", "url": "https://omabrowser.org/oma/group/E1BYM5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q6DH74-1", "protein_name": "U4/U6.U5 small nuclear ribonucleoprotein 27 kDa protein", "gene_name": "snrnp27", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MGRSRSRTPPRRERRRSRSSSRDRERRRRERERSRSRDRDRRRSRSRSPHRRRSRSPRRHRSSSLSPLRQKDRRDDDRKDVKEKPAKVHQISAEDMQGKTEEEIEMMKLMGFGSFETSKGKKKDGSIKAFAVNVSQKRKYRQYMNRKGGFNRPLDFIA", "length": 158 }, "evidence": [ { "id": "E1BYM5", "url": "https://omabrowser.org/oma/group/E1BYM5/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q8K194-1", "protein_name": "U4/U6.U5 small nuclear ribonucleoprotein 27 kDa protein", "gene_name": "Snrnp27", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGRSRSRSPRRERRRSRSTSRDRERRRRERSRSRERDRRRSRSRSPHRRRSRSPRRHRSTSPSPSRLKERRDEEKKETKEIKNKERQITEEDLEGKTEEEIEMMKLMGFASFDSTKGKKVDGSVNAYAINVSQKRKYRQYMNRKGGFNRPLDFIA", "length": 155 }, "evidence": [ { "id": "E1BYM5", "url": "https://omabrowser.org/oma/group/E1BYM5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8WVK2-1", "protein_name": "U4/U6.U5 small nuclear ribonucleoprotein 27 kDa protein", "gene_name": "SNRNP27", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGRSRSRSPRRERRRSRSTSRERERRRRERSRSRERDRRRSRSRSPHRRRSRSPRRHRSTSPSPSRLKERRDEEKKETKETKSKERQITEEDLEGKTEEEIEMMKLMGFASFDSTKGKKVDGSVNAYAINVSQKRKYRQYMNRKGGFNRPLDFIA", "length": 155 }, "evidence": [ { "id": "E1BYM5", "url": "https://omabrowser.org/oma/group/E1BYM5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9FIE4-1", "protein_name": "U4/U6.U5 small nuclear ribonucleoprotein", "gene_name": "MSF19.3", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSERDRRERERDKDREPDRDRRRGRDDRDRDRDRDRERDRERDRDRGLRNKKSRSRTPDHHARARHVRSPERYRSRSRSIDRDRDRDRQRHHRRRSPSPDAPSRKRPRQGSVDDEKERNRKRVVTDSVDENASTITKKKDKQPSDAADNGGGEDEEGMDVNEIEMMKMLGIPTGFDSTKGKPVAGADVSGIRAVTKRQPRQYMNRRGGFNRPLPAERNR", "length": 219 }, "evidence": [ { "id": "E1BYM5", "url": "https://omabrowser.org/oma/group/E1BYM5/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E1BYM5", "url": "https://www.uniprot.org/uniprotkb/E1BYM5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "mRNA processing", "id": "GO:0006397", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006397", "evidence": [ { "database": "UniProtKB", "id": "E1BYM5", "url": "https://www.uniprot.org/uniprotkb/E1BYM5" } ], "pmid": "" }, { "name": "RNA splicing", "id": "GO:0008380", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008380", "evidence": [ { "database": "UniProtKB", "id": "E1BYM5", "url": "https://www.uniprot.org/uniprotkb/E1BYM5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 131, "end_pos": 133, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BYM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BYM5" }, { "id": "PF08648", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08648" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "U4/U6.U5 small nuclear ribonucleoprotein 27kDa protein", "eco_id": "ECO_0000259", "start_pos": 99, "end_pos": 154, "start_aa": "Glu", "end_aa": "Phe", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 131, "end_pos": 133 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1C6K9-1", "uniprot_ac": "E1C6K9", "uniprot_id": "E1C6K9_CHICK", "mass": { "chemical_mass": 66299.0, "monoisotopic_mass": 66299.0 }, "refseq": { "ac": "XP_015145688", "name": "nuclear receptor subfamily 4 group A member 2 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015145688" }, "gene_names": [ { "name": "NR4A2", "type": "recommended", "evidence": [ { "id": "E1C6K9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C6K9" } ] }, { "name": "NR4A2", "type": "synonym", "evidence": [ { "id": "XP_015145688", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015145688" } ] } ], "protein_names": [ { "name": "Nuclear receptor subfamily 4 group A member 2", "type": "recommended", "evidence": [ { "id": "E1C6K9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C6K9/entry#names_and_taxonomy" } ] }, { "name": "nuclear receptor subfamily 4 group A member 2 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_015145688", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015145688" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052538.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015145688", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015145688" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1C6K9", "url": "https://www.uniprot.org/uniprotkb/E1C6K9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "NR4A2", "url": "https://www.uniprot.org/uniprotkb/E1C6K9", "locus": { "chromosome": "7", "start_pos": 35644137, "end_pos": 35650101, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010010499", "url": "https://www.ensembl.org/id/ENSGALG00010010499" } ] } } ], "crossref": [ { "id": "E1C6K9", "url": "https://alphafold.ebi.ac.uk/entry/E1C6K9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000012538", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000012538", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd06969", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06969", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd07071", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07071", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "424320", "url": "https://www.ncbi.nlm.nih.gov/gene/424320", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000536", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000536", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001628", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001628", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001723", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001723", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003070", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003070", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003073", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003073", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013088", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013088", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035500", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035500", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:424320", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424320", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "EDIPMHN", "url": "https://omabrowser.org/oma/group/EDIPMHN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5NYR5", "url": "https://www.orthodb.org/?gene=A0A1D5NYR5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1C6K9", "url": "https://www.orthodb.org/?gene=E1C6K9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24085", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24085", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24085:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24085:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00104", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00104", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00105", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00105", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-383280", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-383280", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_015145688", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015145688", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5NYR5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYR5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5NYR5-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYR5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C6K9", "url": "https://www.uniprot.org/uniprotkb/E1C6K9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C6K9-1", "url": "https://www.uniprot.org/uniprotkb/E1C6K9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPCVQAQYGSSPQGASPASQSYSYHSSGEYSSDFLTPEFVKFSMDLTNTEITATTSLPSFSTFMDNYNSSYDVKPPCLYQMPLSGQQSSIKVEDIQMHGYQQHGHLPPQPDDVMAHSGSVYYKPSSPPTPSTPGFQVQHGPVWDDAGSLHNFHPNYVATTHMIEQRKAPVSRLSLFSFKQSPPGTPVSSCQMRFDGPLHVPMNAEPAGPHHGVDGQPFAVPSPIRKQPAMAFPGLPLGHAPQLLDSQVPSPPSRGSPSNEGLCAVCGDNAACQHYGVRTCEGCKGFFKRTVQKNAKYVCLANKNCPVDKRRRNRCQYCRFQKCLAVGMVKEVVRTDSLKGRRGRLPSKPKSPQEPSPPSPPVSLISALVRAHVDSNPAMTSLDYSRFQANPDYQMSGDDTQHIQQFYDLLTGSMEIIRGWAEKIPGFTDLPKTDQDLLFESAFLELFVLRLAYRSNPVEGKLIFCNGVVLHRLQCVRGFGEWIDSIVEFSSNLQNMNIDISAFSCIAALAMVTERHGLKEPKRVEELQNKIVNCLKDHVTFNNGGLNRPNYLSKLLGKLPELRTLCTQGLQRIFYLKLEDLVPPPAIIDKLFLDTLPF", "length": 598, "header": "tr|E1C6K9-1|E1C6K9_CHICK Isoform 1 of Nuclear receptor subfamily 4 group A member 2 OS=Gallus gallus OX=9031 GN=NR4A2 PE=3 SV=1 CANONICAL=E1C6K9-1" }, "isoforms": [ { "isoform_ac": "A0A1D5NYR5-1", "url": "https://www.uniprot.org/uniprotkb/E1C6K9/entry#A0A1D5NYR5-1", "sequence": { "sequence": "MPAPLSAMPCVQAQYGSSPQGASPASQSYSYHSSGEYSSDFLTPEFVKFSMDLTNTEITATTSLPSFSTFMDNYNSSYDVKPPCLYQMPLSGQQSSIKVEDIQMHGYQQHGHLPPQPDDVMAHSGSVYYKPSSPPTPSTPGFQVQHGPVWDDAGSLHNFHPNYVATTHMIEQRKAPVSRLSLFSFKQSPPGTPVSSCQMRFDGPLHVPMNAEPAGPHHGVDGQPFAVPSPIRKQPAMAFPGLPLGHAPQLLDSQVPSPPSRGSPSNEGLCAVCGDNAACQHYGVRTCEGCKGFFKRTVQKNAKYVCLANKNCPVDKRRRNRCQYCRFQKCLAVGMVKEVVRTDSLKGRRGRLPSKPKSPQEPSPPSPPVSLISALVRAHVDSNPAMTSLDYSRFQANPDYQMSGDDTQHIQQFYDLLTGSMEIIRGWAEKIPGFTDLPKTDQDLLFESAFLELFVLRLAYRSNPVEGKLIFCNGVVLHRLQCVRGFGEWIDSIVEFSSNLQNMNIDISAFSCIAALAMVTERHGLKEPKRVEELQNKIVNCLKDHVTFNNGGLNRPNYLSKLLGKLPELRTLCTQGLQRIFYLKLEDLVPPPAIIDKLFLDTLPF", "length": 605, "header": "tr|A0A1D5NYR5-1|A0A1D5NYR5_CHICK Computationally mapped isoform of Nuclear receptor subfamily 4 group A member 2 OS=Gallus gallus OX=9031 GN=NR4A2 PE=3 SV=1 CANONICAL=E1C6K9-1" }, "locus": { "chromosome": "7", "start_pos": 35649730, "end_pos": 35645141, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010025070.1", "url": "https://www.ensembl.org/id/ENSGALT00010025070.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010014239.1", "url": "https://www.ensembl.org/id/ENSGALP00010014239.1" } ] } }, { "isoform_ac": "E1C6K9-1", "url": "https://www.uniprot.org/uniprotkb/E1C6K9/entry#E1C6K9-1", "sequence": { "sequence": "MPCVQAQYGSSPQGASPASQSYSYHSSGEYSSDFLTPEFVKFSMDLTNTEITATTSLPSFSTFMDNYNSSYDVKPPCLYQMPLSGQQSSIKVEDIQMHGYQQHGHLPPQPDDVMAHSGSVYYKPSSPPTPSTPGFQVQHGPVWDDAGSLHNFHPNYVATTHMIEQRKAPVSRLSLFSFKQSPPGTPVSSCQMRFDGPLHVPMNAEPAGPHHGVDGQPFAVPSPIRKQPAMAFPGLPLGHAPQLLDSQVPSPPSRGSPSNEGLCAVCGDNAACQHYGVRTCEGCKGFFKRTVQKNAKYVCLANKNCPVDKRRRNRCQYCRFQKCLAVGMVKEVVRTDSLKGRRGRLPSKPKSPQEPSPPSPPVSLISALVRAHVDSNPAMTSLDYSRFQANPDYQMSGDDTQHIQQFYDLLTGSMEIIRGWAEKIPGFTDLPKTDQDLLFESAFLELFVLRLAYRSNPVEGKLIFCNGVVLHRLQCVRGFGEWIDSIVEFSSNLQNMNIDISAFSCIAALAMVTERHGLKEPKRVEELQNKIVNCLKDHVTFNNGGLNRPNYLSKLLGKLPELRTLCTQGLQRIFYLKLEDLVPPPAIIDKLFLDTLPF", "length": 598, "header": "tr|E1C6K9-1|E1C6K9_CHICK Isoform 1 of Nuclear receptor subfamily 4 group A member 2 OS=Gallus gallus OX=9031 GN=NR4A2 PE=3 SV=1 CANONICAL=E1C6K9-1" }, "locus": { "chromosome": "7", "start_pos": 35648783, "end_pos": 35645141, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010025066.1", "url": "https://www.ensembl.org/id/ENSGALT00010025066.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010014238.1", "url": "https://www.ensembl.org/id/ENSGALP00010014238.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 129, "start_aa": "Thr", "end_pos": 129, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr129", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 132, "start_aa": "Thr", "end_pos": 132, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr132", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:424320", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424320", "resource": "KEGG Pathway" }, { "id": "R-GGA-383280", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-383280", "resource": "Reactome", "description": "Nuclear Receptor transcription pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287A395-1", "protein_name": "Nuclear receptor subfamily 4 group A member 2", "gene_name": "NR4A2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MPCVQAQYGSSPQGASPASQSYSYHSSGEYSSDFLTPEFVKFSMDLTNTEITATTSLPSFSTFMDNYSTGYDVKPPCLYQMPLSGQQSSIKVEDIQMHNYQQHSHLPPQSEEMMPHSGSVYYKPSSPPTPTTPGFQVQHSPMWDDPGSLHNFHQNYVATTHMIEQRKTPVSRLSLFSFKQSPPGTPVSSCQMRFDGPLHVPMNPEPAGSHHVVDGQTFAVPNPIRKPASMGFPGLQISHASQLLDTQVPSPPSRGSPSNEGLCAVCGDNAACQHYGVRTCEGCKGFFKRTVQKNAKYVCLANKNCPVDKRRRNRCQYCRFQKCLAVGMVKEVVRTDSLKGRRGRLPSKPKSPQEPSPPSPPVSLISALVRAHVDSNPAMTSLDYSRFQANPDYQMSGDDTQHIQQFYDLLTGSMEIIRGWAEKIPGFADLPKADQDLLFESAFLELFVLRLAYRSNPVEGKLIFCNGVVLHRLQCVRGFGEWIDSIVEFSSNLQNMNIDISAFSCIAALAMVTERHGLKEPKRVEELQNKIVNCLKDHVTFNNGGLNRPNYLSKLLGKLPELRTLCTQGLQRIFYLKLEDLVPPPAIIDKLFLDTLPF", "length": 598 }, "evidence": [ { "id": "E1C6K9", "url": "https://omabrowser.org/oma/group/E1C6K9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3HT26-1", "protein_name": "Nuclear receptor subfamily 4 group A member 2", "gene_name": "Nr4a2", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MPCVQAQYGSSPQGASPASQSYSYHSSGEYSSDFLTPEFVKFSMDLTNTEITATTSLPSFSTFMDNYSTGYDVKPPCLYQMPLSGQQSSIKVEDIQMHNYQQHSHLPPQSEEMMPHSGSVYYKPSSPPTPSTPGFQVQHSPMWDDPGSLHNFHQNYVATTHMIEQRKTPVSRLSLFSFKQSPPGTPVSSCQMRFDGPLHVPMNPEPAGSHHVVDGQTFAVPNPIRKPASMGFPGLQIGHASQLLDSQVPSPPSRGSPSNEGLCAVCGDNAACQHYGVRTCEGCKGFFKRTVQKNAKYVCLANKNCPVDKRRRNRCQYCRFQKCLAVGMVKEVVRTDSLKGRRGRLPSKPKSPQDPSPPSPPVSLISALVRAHVDSNPAMTSLDYSRFQANPDYQMSGDDTQHIQQFYDLLTGSMEIIRGWAEKIPGFADLPKADQDLLFESAFLELFVLRLAYRSNPVEGKLIFCNGVVLHRLQCVRGFGEWIDSIVEFSSNLQNMNIDISAFSCIAALAMVTERHGLKEPKRVEELQNKIVNCLKDHVTFNNGGLNRPNYLSKLLGKLPELRTLCTQGLQRIFYLKLEDLVPPPAIIDKLFLDTLPF", "length": 598 }, "evidence": [ { "id": "E1C6K9", "url": "https://omabrowser.org/oma/group/E1C6K9/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P43354-1", "protein_name": "Nuclear receptor subfamily 4 group A member 2", "gene_name": "NR4A2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPCVQAQYGSSPQGASPASQSYSYHSSGEYSSDFLTPEFVKFSMDLTNTEITATTSLPSFSTFMDNYSTGYDVKPPCLYQMPLSGQQSSIKVEDIQMHNYQQHSHLPPQSEEMMPHSGSVYYKPSSPPTPTTPGFQVQHSPMWDDPGSLHNFHQNYVATTHMIEQRKTPVSRLSLFSFKQSPPGTPVSSCQMRFDGPLHVPMNPEPAGSHHVVDGQTFAVPNPIRKPASMGFPGLQIGHASQLLDTQVPSPPSRGSPSNEGLCAVCGDNAACQHYGVRTCEGCKGFFKRTVQKNAKYVCLANKNCPVDKRRRNRCQYCRFQKCLAVGMVKEVVRTDSLKGRRGRLPSKPKSPQEPSPPSPPVSLISALVRAHVDSNPAMTSLDYSRFQANPDYQMSGDDTQHIQQFYDLLTGSMEIIRGWAEKIPGFADLPKADQDLLFESAFLELFVLRLAYRSNPVEGKLIFCNGVVLHRLQCVRGFGEWIDSIVEFSSNLQNMNIDISAFSCIAALAMVTERHGLKEPKRVEELQNKIVNCLKDHVTFNNGGLNRPNYLSKLLGKLPELRTLCTQGLQRIFYLKLEDLVPPPAIIDKLFLDTLPF", "length": 598 }, "evidence": [ { "id": "E1C6K9", "url": "https://omabrowser.org/oma/group/E1C6K9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q06219-1", "protein_name": "Nuclear receptor subfamily 4 group A member 2", "gene_name": "Nr4a2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPCVQAQYGSSPQGASPASQSYSYHSSGEYSSDFLTPEFVKFSMDLTNTEITATTSLPSFSTFMDNYSTGYDVKPPCLYQMPLSGQQSSIKVEDIQMHNYQQHSHLPPQSEEMMPHSGSVYYKPSSPPTPSTPSFQVQHSPMWDDPGSLHNFHQNYVATTHMIEQRKTPVSRLSLFSFKQSPPGTPVSSCQMRFDGPLHVPMNPEPAGSHHVVDGQTFAVPNPIRKPASMGFPGLQIGHASQLLDTQVPSPPSRGSPSNEGLCAVCGDNAACQHYGVRTCEGCKGFFKRTVQKNAKYVCLANKNCPVDKRRRNRCQYCRFQKCLAVGMVKEVVRTDSLKGRRGRLPSKPKSPQDPSPPSPPVSLISALVRAHVDSNPAMTSLDYSRFQANPDYQMSGDDTQHIQQFYDLLTGSMEIIRGWAEKIPGFADLPKADQDLLFESAFLELFVLRLAYRSNPVEGKLIFCNGVVLHRLQCVRGFGEWIDSIVEFSSNLQNMNIDISAFSCIAALAMVTERHGLKEPKRVEELQNKIVNCLKDHVTFNNGGLNRPNYLSKLLGKLPELRTLCTQGLQRIFYLKLEDLVPPPAIIDKLFLDTLPF", "length": 598 }, "evidence": [ { "id": "E1C6K9", "url": "https://omabrowser.org/oma/group/E1C6K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q07917-1", "protein_name": "Nuclear receptor subfamily 4 group A member 2", "gene_name": "Nr4a2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPCVQAQYGSSPQGASPASQSYSYHSSGEYSSDFLTPEFVKFSMDLTNTEITATTSLPSFSTFMDNYSTGYDVKPPCLYQMPLSGQQSSIKVEDIQMHNYQQHSHLPPQSEEMMPHSGSVYYKPSSPPTPSTPGFQVQHSPMWDDPGSLHNFHQNYVATTHMIEQRKTPVSRLSLFSFKQSRPGTPVSSCQMRFDGPLHVPMNPEPAGSHHVVDGQTFAVPNPIRKPASMGFPGLQIGHASQLLDTQVPSPPSRGSPSNEGLCAVCGDNAACQHYGVRTCEGCKGFFKRTVQKNAKYVCLANKNCPVDKRRRNRCQYCRFQKCLAVGMVKEVVRTDSLKGRRGRLPSKPKSPQDPSPPSPPVSLISALVRAHVDSNPAMTSLDYSRFQANPDYQMSGDDTQHIQQFYDLLTGSMEIIRGWAEKIPGFADLPKADQDLLFESAFLELFVLRLAYRSNPVEGKLIFCNGVVLHRLQCVRGFGEWIDSIVEFSSNLQNMNIDISAFSCIAALAMVTERHGLKEPKRVEELQNKIVNCLKDHVTFNNGGLNRPNYLSKLLGKLPELRTLCTQGLQRIFYLKLEDLVPPPAIIDKLFLDTLPF", "length": 598 }, "evidence": [ { "id": "E1C6K9", "url": "https://omabrowser.org/oma/group/E1C6K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q08E53-1", "protein_name": "Nuclear receptor subfamily 4 group A member 2", "gene_name": "NR4A2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MPCVQAQYGSSPQGASPASQSYSYHSSGEYSSDFLTPEFVKFSMDLTNTEITATTSLPSFSTFMDNYSTGYDVKPPCLYQMPLSGQQSSIKVEDIQMHNYQQHSHLPPQSEEMMPHSGSVYYKPSSPPTPTTPGFQVQHSPMWDDPGSLHNFHQNYVATTHMIEQRKTPVSRLSLFSFKQSPPGTPVSSCQMRFDGPLHVPMNPEPAGSHHVVDGQTFAVPNPIRKPASMGFPGLQIGHASQLLDTQVPSPPSRGSPSNEGLCAVCGDNAACQHYGVRTCEGCKGFFKRTVQKNAKYVCLANKNCPVDKRRRNRCQYCRFQKCLAVGMVKEVVRTDSLKGRRGRLPSKPKSPQEPSPPSPPVSLISALVRAHVDSNPAMTSLDYSRFQANPDYQMSGDDTQHIQQFYDLLTGSMEIIRGWAEKIPGFTDLPKADQDLLFESAFLELFVLRLAYRSNPVEGKLIFCNGVVLHRLQCVRGFGEWIDSIVEFSSNLQNMNIDISAFSCIAALAMVTERHGLKEPKRVEELQNKIVNCLKDHVTFNNGGLNRPNYLSKLLGKLPELRTLCTQGLQRIFYLKLEDLVPPPAIIDKLFLDTLPF", "length": 598 }, "evidence": [ { "id": "E1C6K9", "url": "https://omabrowser.org/oma/group/E1C6K9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 8, "go_terms": [ { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "E1C6K9", "url": "https://www.uniprot.org/uniprotkb/E1C6K9" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "E1C6K9", "url": "https://www.uniprot.org/uniprotkb/E1C6K9" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "E1C6K9", "url": "https://www.uniprot.org/uniprotkb/E1C6K9" } ], "pmid": "" }, { "name": "fat cell differentiation", "id": "GO:0045444", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045444", "evidence": [ { "database": "UniProtKB", "id": "E1C6K9", "url": "https://www.uniprot.org/uniprotkb/E1C6K9" } ], "pmid": "" }, { "name": "negative regulation of apoptotic signaling pathway", "id": "GO:2001234", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2001234", "evidence": [ { "database": "UniProtKB", "id": "E1C6K9", "url": "https://www.uniprot.org/uniprotkb/E1C6K9" } ], "pmid": "" }, { "name": "central nervous system neuron differentiation", "id": "GO:0021953", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021953", "evidence": [ { "database": "UniProtKB", "id": "E1C6K9", "url": "https://www.uniprot.org/uniprotkb/E1C6K9" } ], "pmid": "" }, { "name": "dopaminergic neuron differentiation", "id": "GO:0071542", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071542", "evidence": [ { "database": "UniProtKB", "id": "E1C6K9", "url": "https://www.uniprot.org/uniprotkb/E1C6K9" } ], "pmid": "" }, { "name": "cellular response to corticotropin-releasing hormone stimulus", "id": "GO:0071376", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071376", "evidence": [ { "database": "UniProtKB", "id": "E1C6K9", "url": "https://www.uniprot.org/uniprotkb/E1C6K9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E1C6K9", "url": "https://www.uniprot.org/uniprotkb/E1C6K9" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "E1C6K9", "url": "https://www.uniprot.org/uniprotkb/E1C6K9" } ], "pmid": "" }, { "name": "nuclear speck", "id": "GO:0016607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016607", "evidence": [ { "database": "UniProtKB", "id": "E1C6K9", "url": "https://www.uniprot.org/uniprotkb/E1C6K9" } ], "pmid": "" }, { "name": "transcription regulator complex", "id": "GO:0005667", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005667", "evidence": [ { "database": "UniProtKB", "id": "E1C6K9", "url": "https://www.uniprot.org/uniprotkb/E1C6K9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 8, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "E1C6K9", "url": "https://www.uniprot.org/uniprotkb/E1C6K9" } ], "pmid": "" }, { "name": "protein heterodimerization activity", "id": "GO:0046982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046982", "evidence": [ { "database": "UniProtKB", "id": "E1C6K9", "url": "https://www.uniprot.org/uniprotkb/E1C6K9" } ], "pmid": "" }, { "name": "nuclear glucocorticoid receptor binding", "id": "GO:0035259", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035259", "evidence": [ { "database": "UniProtKB", "id": "E1C6K9", "url": "https://www.uniprot.org/uniprotkb/E1C6K9" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "E1C6K9", "url": "https://www.uniprot.org/uniprotkb/E1C6K9" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "E1C6K9", "url": "https://www.uniprot.org/uniprotkb/E1C6K9" } ], "pmid": "" }, { "name": "nuclear receptor activity", "id": "GO:0004879", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004879", "evidence": [ { "database": "UniProtKB", "id": "E1C6K9", "url": "https://www.uniprot.org/uniprotkb/E1C6K9" } ], "pmid": "" }, { "name": "DNA-binding transcription activator activity, RNA polymerase II-specific", "id": "GO:0001228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001228", "evidence": [ { "database": "UniProtKB", "id": "E1C6K9", "url": "https://www.uniprot.org/uniprotkb/E1C6K9" } ], "pmid": "" }, { "name": "sequence-specific DNA binding", "id": "GO:0043565", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043565", "evidence": [ { "database": "UniProtKB", "id": "E1C6K9", "url": "https://www.uniprot.org/uniprotkb/E1C6K9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 68, "end_pos": 70, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 129, 132 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 68, "end_pos": 70 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1NBY2-1", "uniprot_ac": "F1NBY2", "uniprot_id": "F1NBY2_CHICK", "mass": { "chemical_mass": 29547.0, "monoisotopic_mass": 29547.0 }, "refseq": { "ac": "NP_001186461", "name": "receptor expression-enhancing protein 3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186461" }, "gene_names": [ { "name": "REEP3", "type": "recommended", "evidence": [ { "id": "F1NBY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NBY2" } ] }, { "name": "REEP3", "type": "synonym", "evidence": [ { "id": "NP_001186461", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186461" } ] } ], "protein_names": [ { "name": "Receptor expression-enhancing protein", "type": "recommended", "evidence": [ { "id": "F1NBY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NBY2/entry#names_and_taxonomy" } ] }, { "name": "receptor expression-enhancing protein 3", "type": "synonym", "evidence": [ { "id": "NP_001186461", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186461" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: SRR13267659.250233.1, SRR13267661.46.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA103992290, SAMEA103992323 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000227.1. On Dec 9, 2010 this sequence version replaced XP_421536.2.", "evidence": [ { "database": "RefSeq", "id": "NP_001186461", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186461" } ] }, { "annotation": "Microtubule-binding protein required to ensure proper cell division and nuclear envelope reassembly by sequestering the endoplasmic reticulum away from chromosomes during mitosis. Probably acts by clearing the endoplasmic reticulum membrane from metaphase chromosomes.", "evidence": [ { "database": "UniProtKB", "id": "F1NBY2", "url": "https://www.uniprot.org/uniprotkb/F1NBY2#function" }, { "database": "UniProtKB", "id": "ARBA00037282", "url": "https://www.uniprot.org/uniprotkb/ARBA00037282#function" }, { "database": "UniProtKB", "id": "A0A8V0XX11", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XX11#function" }, { "database": "UniProtKB", "id": "A0A8V0Y1J2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y1J2#function" }, { "database": "UniProtKB", "id": "A0A8V0YA15", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YA15#function" }, { "database": "UniProtKB", "id": "A0A8V0YA20", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YA20#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NBY2", "url": "https://www.uniprot.org/uniprotkb/F1NBY2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "REEP3", "url": "https://www.uniprot.org/uniprotkb/F1NBY2", "locus": { "chromosome": "6", "start_pos": 8446659, "end_pos": 8484244, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010009359", "url": "https://www.ensembl.org/id/ENSGALG00010009359" } ] } } ], "crossref": [ { "id": "F1NBY2", "url": "https://alphafold.ebi.ac.uk/entry/F1NBY2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000002904", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000002904", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "423654", "url": "https://www.ncbi.nlm.nih.gov/gene/423654", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004345", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004345", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:423654", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423654", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PIGQRHY", "url": "https://omabrowser.org/oma/group/PIGQRHY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XX11", "url": "https://www.orthodb.org/?gene=A0A8V0XX11", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y1J2", "url": "https://www.orthodb.org/?gene=A0A8V0Y1J2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YA15", "url": "https://www.orthodb.org/?gene=A0A8V0YA15", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YA20", "url": "https://www.orthodb.org/?gene=A0A8V0YA20", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NBY2", "url": "https://www.orthodb.org/?gene=F1NBY2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12300", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12300", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12300:SF39", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12300:SF39", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03134", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03134", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001186461", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186461", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0XX11", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XX11", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XX11-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XX11-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y1J2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y1J2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y1J2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y1J2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YA15", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YA15", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YA15-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YA15-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YA20", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YA20", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YA20-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YA20-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NBY2", "url": "https://www.uniprot.org/uniprotkb/F1NBY2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NBY2-1", "url": "https://www.uniprot.org/uniprotkb/F1NBY2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVSWMISRAVVLVFGMLYPAYYSYKAVKTKNVKEYVRWMMYWIVFALYTVTETITDLTISWFPLYYELKIAFVIWLLSPYTRGASLMYRKFLHPLLSSKEREIDEYIVQAKERGYETMVNFGRQGLNLAATAAVTAAVKSQGAITEKLRSFSMHDLTTIQGDEPVGQRPYQTLPETKKKTRASANESAGFPLEKNPGDDRTDEEVEGTHSEDEMFAQRGLRRTQSMKSVKTVKGRKEIRYGSLKYRVKKRPNVYF", "length": 255, "header": "tr|F1NBY2-1|F1NBY2_CHICK Isoform 1 of Receptor expression-enhancing protein OS=Gallus gallus OX=9031 GN=REEP3 PE=1 SV=2 CANONICAL=F1NBY2-1" }, "isoforms": [ { "isoform_ac": "A0A8V0XX11-1", "url": "https://www.uniprot.org/uniprotkb/F1NBY2/entry#A0A8V0XX11-1", "sequence": { "sequence": "METTELYGFTRQGYFWYQVRWMMYWIVFALYTVTETITDLTISWFPLYYELKIAFVIWLLSPYTRGASLMYRKFLHPLLSSKEREIDEYIVQAKERGYETMVNFGRQGLNLAATAAVTAAVKSQGAITEKLRSFSMHDLTTIQGDEPVGQRPYQTLPETKKKTRASANESAGFPLEKNPGDDRTDEEVEGTHSEDEMFAQRGLRRTQSMKSVKTVKGRKEIRYGSLKYRVKKRPNVYF", "length": 238, "header": "tr|A0A8V0XX11-1|A0A8V0XX11_CHICK Computationally mapped isoform of Receptor expression-enhancing protein OS=Gallus gallus OX=9031 GN=REEP3 PE=1 SV=1 CANONICAL=F1NBY2-1" }, "locus": { "chromosome": "6", "start_pos": 8466517, "end_pos": 8450428, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010022289.1", "url": "https://www.ensembl.org/id/ENSGALT00010022289.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010012814.1", "url": "https://www.ensembl.org/id/ENSGALP00010012814.1" } ] } }, { "isoform_ac": "A0A8V0Y1J2-1", "url": "https://www.uniprot.org/uniprotkb/F1NBY2/entry#A0A8V0Y1J2-1", "sequence": { "sequence": "MVSWMISRAVVRWMMYWIVFALYTVTETITDLTISWFPLYYELKIAFVIWLLSPYTRGASLMYRKFLHPLLSSKEREIDEYIVQAKERGYETMVNFGRQGLNLAATAAVTAAVKSQGAITEKLRSFSMHDLTTIQGDEPVGQRPYQTLPETKKKTRASANESAGFPLEKNPGDDRTDEEVEGTHSEDEMFAQRGLRRTQSMKSVKTVKGRKEIRYGSLKYRVKKRPNVYF", "length": 230, "header": "tr|A0A8V0Y1J2-1|A0A8V0Y1J2_CHICK Computationally mapped isoform of Receptor expression-enhancing protein OS=Gallus gallus OX=9031 GN=REEP3 PE=1 SV=1 CANONICAL=F1NBY2-1" }, "locus": { "chromosome": "6", "start_pos": 8484137, "end_pos": 8450428, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010022302.1", "url": "https://www.ensembl.org/id/ENSGALT00010022302.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010012824.1", "url": "https://www.ensembl.org/id/ENSGALP00010012824.1" } ] } }, { "isoform_ac": "A0A8V0YA15-1", "url": "https://www.uniprot.org/uniprotkb/F1NBY2/entry#A0A8V0YA15-1", "sequence": { "sequence": "MEDAPVANHTGKGNWMGSAKLVFGMLYPAYYSYKAVKTKNVKEYVRWMMYWIVFALYTVTETITDLTISWFPLYYELKIAFVIWLLSPYTRGASLMYRKFLHPLLSSKEREIDEYIVQAKERGYETMVNFGRQGLNLAATAAVTAAVKSQGAITEKLRSFSMHDLTTIQGDEPVGQRPYQTLPETKKKTRASANESAGFPLEKNPGDDRTDEEVEGTHSEDEMFAQRGLRRTQSMKSVKTVKGRKEIRYGSLKYRVKKRPNVYF", "length": 264, "header": "tr|A0A8V0YA15-1|A0A8V0YA15_CHICK Computationally mapped isoform of Receptor expression-enhancing protein OS=Gallus gallus OX=9031 GN=REEP3 PE=1 SV=1 CANONICAL=F1NBY2-1" }, "locus": { "chromosome": "6", "start_pos": 8472665, "end_pos": 8450428, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010022293.1", "url": "https://www.ensembl.org/id/ENSGALT00010022293.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010012816.1", "url": "https://www.ensembl.org/id/ENSGALP00010012816.1" } ] } }, { "isoform_ac": "A0A8V0YA20-1", "url": "https://www.uniprot.org/uniprotkb/F1NBY2/entry#A0A8V0YA20-1", "sequence": { "sequence": "MLYPAYYSYKAVKTKNVKEYVRWMMYWIVFALYTVTETITDLTISWFPLYYELKIAFVIWLLSPYTRGASLMYRKFLHPLLSSKEREIDEYIVQAKERGYETMVNFGRQGLNLAATAAVTAAVKSQGAITEKLRSFSMHDLTTIQGDEPVGQRPYQTLPETKKKTRASANESAGFPLEKNPGDDRTDEEVEGTHSEDEMFAQRGLRRTQSMKSVKTVKGRKEIRYGSLKYRVKKRPNVYF", "length": 240, "header": "tr|A0A8V0YA20-1|A0A8V0YA20_CHICK Computationally mapped isoform of Receptor expression-enhancing protein OS=Gallus gallus OX=9031 GN=REEP3 PE=1 SV=1 CANONICAL=F1NBY2-1" }, "locus": { "chromosome": "6", "start_pos": 8469092, "end_pos": 8450428, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010022299.1", "url": "https://www.ensembl.org/id/ENSGALT00010022299.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010012821.1", "url": "https://www.ensembl.org/id/ENSGALP00010012821.1" } ] } }, { "isoform_ac": "F1NBY2-1", "url": "https://www.uniprot.org/uniprotkb/F1NBY2/entry#F1NBY2-1", "sequence": { "sequence": "MVSWMISRAVVLVFGMLYPAYYSYKAVKTKNVKEYVRWMMYWIVFALYTVTETITDLTISWFPLYYELKIAFVIWLLSPYTRGASLMYRKFLHPLLSSKEREIDEYIVQAKERGYETMVNFGRQGLNLAATAAVTAAVKSQGAITEKLRSFSMHDLTTIQGDEPVGQRPYQTLPETKKKTRASANESAGFPLEKNPGDDRTDEEVEGTHSEDEMFAQRGLRRTQSMKSVKTVKGRKEIRYGSLKYRVKKRPNVYF", "length": 255, "header": "tr|F1NBY2-1|F1NBY2_CHICK Isoform 1 of Receptor expression-enhancing protein OS=Gallus gallus OX=9031 GN=REEP3 PE=1 SV=2 CANONICAL=F1NBY2-1" }, "locus": { "chromosome": "6", "start_pos": 8484137, "end_pos": 8450428, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010022305.1", "url": "https://www.ensembl.org/id/ENSGALT00010022305.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010012827.1", "url": "https://www.ensembl.org/id/ENSGALP00010012827.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 135, "start_aa": "Thr", "end_pos": 135, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr135", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:423654", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423654", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287ARX4-1", "protein_name": "Receptor expression-enhancing protein", "gene_name": "REEP3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MVSWMISRAVVLVFGMLYPAYYSYKAVKTKNVKEYVRWMMYWIVFALYTVIETVADQTVAWFPLYYELKIAFVIWLLSPYTKGASLIYRKFLHPLLSAKEREIDDYIVQAKERGYETMVNFGRQGLNLAATAAVTAAVKSQGAITERLRSFSMHDLTAIQGDEPVGQRPYQPLPETKKKSKPASSESAGYGIPLRDGDEKTDEEADRPYSDDEMLTHKGLRRSQSMKSVKAVKGRKEVRYGSLKYKVKKRPQVYF", "length": 255 }, "evidence": [ { "id": "F1NBY2", "url": "https://omabrowser.org/oma/group/F1NBY2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8I5ZZG2-1", "protein_name": "Receptor accessory protein 3", "gene_name": "Reep3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAGSAPWSRSPTRGGLCSASPRPPLRSSAALLGSSAPPLPGAARGGLCSAPRRAPGCGSRSRSRGPRCAAPPCAGSADAERGRPAGLRMRPSLCHQVYRVAVSVRGARRLVTCRRRRRRDPCQSPGCRVVLRGPEVTREGACSRKVGQTLTRRALCGKKCLRRGRRRLVFGMLYPAYYSYKAVKTKNVKEYVRWMMYWIVFALYTVIETVADQTLAWFPLYYELKIAFVIWLLSPYTRGASLIYRKFLHPLLSSKEREIDDYIVQAKERGYETMVNFGRQGLNLAAAAAVTAAVKSQGAITERLRSFSMHDLTAIQGDEPVGHRPYQTLPEAKRKGKQATESPAYGIPLKDGSEQTDEEAEGPFSDDEMVTHKGLRRSQSMKSVKTIKGRKEVRYGSLKYKVKKRPQVYF", "length": 410 }, "evidence": [ { "id": "F1NBY2", "url": "https://omabrowser.org/oma/group/F1NBY2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6NUK4-1", "protein_name": "Receptor expression-enhancing protein 3", "gene_name": "REEP3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVSWMISRAVVLVFGMLYPAYYSYKAVKTKNVKEYVRWMMYWIVFALYTVIETVADQTVAWFPLYYELKIAFVIWLLSPYTKGASLIYRKFLHPLLSSKEREIDDYIVQAKERGYETMVNFGRQGLNLAATAAVTAAVKSQGAITERLRSFSMHDLTTIQGDEPVGQRPYQPLPEAKKKSKPAPSESAGYGIPLKDGDEKTDEEAEGPYSDNEMLTHKGLRRSQSMKSVKTTKGRKEVRYGSLKYKVKKRPQVYF", "length": 255 }, "evidence": [ { "id": "F1NBY2", "url": "https://omabrowser.org/oma/group/F1NBY2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q7ZVX5-1", "protein_name": "Receptor expression-enhancing protein 3", "gene_name": "reep3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MVSWMISRSVVLVFGNLYPAYYSYKAVKTKNVKEYVRWMMYWIVFALFTVVETVADLTIAWFPLYYEIKIAFVIWLLSPYTRGASVIYRKALHPLLSSKEREIDDYIVQAKERSYETMVNFGKQGLTIAATAAVSAAVKGQGAITEKLRSFSMHDLTQIPQDDGYSSYASNPARRAIMDQPDGAEYYHGDDDDRSDEDSKPVFSEDEAVSHHGLRRSQSVKVTRSKLRRDARYGSLKIKGRKRPGINATTYSNMES", "length": 256 }, "evidence": [ { "id": "F1NBY2", "url": "https://omabrowser.org/oma/group/F1NBY2/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q99KK1-1", "protein_name": "Receptor expression-enhancing protein 3", "gene_name": "Reep3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVSWMISRAVVLVFGMLYPAYYSYKAVKTKNVKEYVRWMMYWIVFALYTVIETVADQTLAWFPLYYELKIAFVIWLLSPYTRGASLIYRKFLHPLLSSKEREIDDYIVQAKERGYETMVNFGRQGLNLAAAAAVTAAVKSQGAITERLRSFSMHDLTAIQGDEPVGHRPYQTLPEAKRKGKQATESPAYGIPLKDGSEQTDEEAEGPFSDDEMVTHKALRRSQSMKSVKTIKGRKEVRYGSLKYKVKKRPQVYF", "length": 254 }, "evidence": [ { "id": "F1NBY2", "url": "https://omabrowser.org/oma/group/F1NBY2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "microtubule", "id": "GO:0005874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005874", "evidence": [ { "database": "UniProtKB", "id": "F1NBY2", "url": "https://www.uniprot.org/uniprotkb/F1NBY2" } ], "pmid": "" 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"Protein" ] }, { "id": "F1NBD7-1", "url": "https://www.uniprot.org/uniprotkb/F1NBD7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELHHPNIVCLQDVLMQDARLYLIFEFLSMDLKKYLDTIPSGQYLDRSRVKSYLYQILQGIVFCHSRRVLHRDLKPQNLLIDDKGVIKLADFGLARAFGIPVRVYTHEVVTLWYRSPEVLLGSARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNDVWPDVESLQDYKNTFPKWKPGSLGTHVQNLDEDGLDLLSKMLIYDPAKRISGKMALNHPYFDDLDKSTLPANLIKKF", "length": 303, "header": "tr|F1NBD7-1|F1NBD7_CHICK Isoform 1 of Cyclin dependent kinase 1 OS=Gallus gallus OX=9031 GN=CDK1 PE=1 SV=1 CANONICAL=F1NBD7-1" }, "isoforms": [ { "isoform_ac": "A0A8V0XY56-1", "url": "https://www.uniprot.org/uniprotkb/F1NBD7/entry#A0A8V0XY56-1", "sequence": { "sequence": 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"evidence": [ { "id": "17989", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/17989" } ] }, { "id": "46608", "name": "", "equation": "L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A1D5PUY5-1", "Q6U1I9-1", "A0A8V0XNJ2-1", "A0A8V0ZUL0-1", "A0A8V0ZT63-1", "A0A8V1ACW2-1", "A0A8V0Z1X0-1", "A0A8V0YHN2-1", "A0A8V0YMN5-1", "A0A8V0Z807-1", "A0A8V0Z930-1", "A0A8V0YFR6-1", "A0A1D5P0M9-1", "A0A8V0ZBN6-1", "A0A3Q2U9U9-1", "A0A8V0YRC9-1", "A0A8V0YXZ5-1", "A0A8V0ZSP4-1", "A0A8V0ZXQ9-1", "A0A8V0ZZV3-1", "A0A8V1ADF0-1", "A0A8V0ZFT3-1", "A0A8V0ZA45-1", "A0A8V0ZB33-1", "A0A8V0ZD70-1", "A0A8V0Z8T4-1", "R4GIN8-1", "A0A8V0ZK64-1", "A0A8V0ZC16-1", "A0A8V0ZWW1-1", "E1BY69-1", "A0A8V0ZDW9-1", "A0A8V0ZKA2-1", "A0A3Q3B2F1-1", "F1P356-1", "A0A8V1AHA8-1", "Q8QFP8-1", "F1P011-1", "A0A8V0YKK3-1", "A0A1D5NWT4-1", "A0A1D5PMQ7-1", "E1BWA3-1", "F1NVF2-1", 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ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X1Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X1Q7" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X1Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X1Q7" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0X1Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X1Q7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0X1Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X1Q7" } ] } ] }, { "uniprot_ac": "A0A8V0X2Y2", "gene_name": "MAPK12", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X2Y2", "database": "UniProtKB", "url": 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"ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0X4P0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X4P0" } ] } ] }, { "uniprot_ac": "A0A8V0X4Q3", "gene_name": "ICK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X4Q3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X4Q3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0X4Q3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X4Q3" } ] } ] }, { "uniprot_ac": "A0A8V0X5Z8", "gene_name": "NEK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X5Z8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X5Z8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0X5Z8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X5Z8" } ] } ] }, { "uniprot_ac": "A0A8V0X6T4", "gene_name": "LOC107050692", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X6T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X6T4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0X6T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X6T4" } ] } ] }, { "uniprot_ac": "A0A8V0X7R2", "gene_name": "SBK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X7R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X7R2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0X7R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X7R2" } ] } ] }, { "uniprot_ac": "A0A8V0X8M1", "gene_name": "TRIO", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X8M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X8M1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0X8M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X8M1" } ] } ] }, { "uniprot_ac": "A0A8V0XAH9", "gene_name": "NEK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XAH9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XAH9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XAH9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XAH9" } ] } ] }, { "uniprot_ac": "A0A8V0XB58", "gene_name": "CAMK2D", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XB58", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XB58" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V0XB58", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XB58" } ] } ] }, { "uniprot_ac": "A0A8V0XBZ0", "gene_name": "STK32C", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XBZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XBZ0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XBZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XBZ0" } ] } ] }, { "uniprot_ac": "A0A8V0XCS0", "gene_name": "PRKG2", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XCS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCS0" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "A0A8V0XCS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCS0" } ] } ] }, { "uniprot_ac": "A0A8V0XCV5", "gene_name": "MAP3K7", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XCV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCV5" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0XCV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCV5" } ] } ] }, { "uniprot_ac": "A0A8V0XCY6", "gene_name": "TTK", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XCY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCY6" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V0XCY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCY6" } ] } ] }, { "uniprot_ac": "A0A8V0XDR5", "gene_name": "IRAK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XDR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XDR5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XDR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XDR5" } ] } ] }, { "uniprot_ac": "A0A8V0XE48", "gene_name": "ROCK2", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XE48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XE48" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "A0A8V0XE48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XE48" } ] } ] }, { "uniprot_ac": "A0A8V0XEA3", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XEA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEA3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XEA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEA3" } ] } ] }, { "uniprot_ac": "A0A8V0XFW1", "gene_name": "SGK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XFW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XFW1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XFW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XFW1" } ] } ] }, { "uniprot_ac": "A0A8V0XFX2", "gene_name": "NEK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XFX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XFX2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XFX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XFX2" } ] } ] }, { "uniprot_ac": "A0A8V0XG21", "gene_name": "LOC107050335", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XG21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XG21" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XG21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XG21" } ] } ] }, { "uniprot_ac": "A0A8V0XI18", "gene_name": "ATM", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XI18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XI18" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XI18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XI18" } ] } ] }, { "uniprot_ac": "A0A8V0XKG0", "gene_name": "NEK9", "activity": [ { "ec_number": "2.7.11.38", "activity": "L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XKG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XKG0" } ] }, { "ec_number": "2.7.11.38", "activity": "", "evidence": [ { "id": "A0A8V0XKG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XKG0" } ] } ] }, { "uniprot_ac": "A0A8V0XLV6", "gene_name": "MAPK10", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XLV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XLV6" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0XLV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XLV6" } ] } ] }, { "uniprot_ac": "A0A8V0XMT1", "gene_name": "MOS", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XMT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMT1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XMT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMT1" } ] } ] }, { "uniprot_ac": "A0A8V0XMX8", "gene_name": "MASTL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XMX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMX8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XMX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMX8" } ] } ] }, { "uniprot_ac": "A0A8V0XND6", "gene_name": "RIOK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XND6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XND6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XND6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XND6" } ] } ] }, { "uniprot_ac": "A0A8V0XNJ2", "gene_name": "CDK8", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XNJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNJ2" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XNJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNJ2" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0XNJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNJ2" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A8V0XNJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNJ2" } ] } ] }, { "uniprot_ac": "A0A8V0XNK8", "gene_name": "PRKCQ", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XNK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNK8" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V0XNK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNK8" } ] } ] }, { "uniprot_ac": "A0A8V0XQ14", "gene_name": "PLK4", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XQ14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ14" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0A8V0XQ14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ14" } ] } ] }, { "uniprot_ac": "A0A8V0XQ97", "gene_name": "CDK14", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XQ97", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ97" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0XQ97", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ97" } ] } ] }, { "uniprot_ac": "A0A8V0XQQ4", "gene_name": "NME7", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQQ4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQQ4" } ] } ] }, { "uniprot_ac": "A0A8V0XQS0", "gene_name": "STK24", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XQS0", "database": 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"A0A8V0YFL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFL1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0YFL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFL1" } ] } ] }, { "uniprot_ac": "A0A8V0YFP8", "gene_name": "RIPK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YFP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFP8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YFP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFP8" } ] } ] }, { "uniprot_ac": "A0A8V0YFR6", "gene_name": "TNIK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YFR6", "database": "UniProtKB", "url": 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"ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YHH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHH2" } ] } ] }, { "uniprot_ac": "A0A8V0YHN2", "gene_name": "RPS6KA1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YHN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHN2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YHN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHN2" } ] } ] }, { "uniprot_ac": "A0A8V0YIV6", "gene_name": "DYRK1A", "activity": [ { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] }, { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] } ] }, { "uniprot_ac": "A0A8V0YJP9", "gene_name": "RIOK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YJP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJP9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YJP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJP9" } ] } ] }, { "uniprot_ac": "A0A8V0YK18", "gene_name": "CDC42BPB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YK18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK18" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YK18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK18" } ] } ] }, { "uniprot_ac": "A0A8V0YKK3", "gene_name": "MAP4K4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YKK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKK3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YKK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKK3" } ] } ] }, { "uniprot_ac": "A0A8V0YLV1", "gene_name": "MARK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YLV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLV1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YLV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLV1" } ] } ] }, { "uniprot_ac": "A0A8V0YM22", "gene_name": "MYO3AL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YM22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM22" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YM22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM22" } ] } ] }, { "uniprot_ac": "A0A8V0YM96", "gene_name": "STK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YM96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM96" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YM96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM96" } ] } ] }, { "uniprot_ac": "A0A8V0YMB3", "gene_name": "STK32A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YMB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMB3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YMB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMB3" } ] } ] }, { "uniprot_ac": "A0A8V0YMN5", "gene_name": "BRAF", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YMN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMN5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YMN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMN5" } ] } ] }, { "uniprot_ac": "A0A8V0YNI5", "gene_name": "NIM1K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YNI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNI5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YNI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNI5" } ] } ] }, { "uniprot_ac": "A0A8V0YRC9", "gene_name": "TNK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YRC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRC9" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YRC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRC9" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0YRC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRC9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YRC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRC9" } ] } ] }, { "uniprot_ac": "A0A8V0YRN4", "gene_name": "GAK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YRN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRN4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YRN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRN4" } ] } ] }, { "uniprot_ac": "A0A8V0YSH3", "gene_name": "RPS6KA6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YSH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSH3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YSH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSH3" } ] } ] }, { "uniprot_ac": "A0A8V0YTI1", "gene_name": "TSSK6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTI1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTI1" } ] } ] }, { "uniprot_ac": "A0A8V0YTL9", "gene_name": "VRK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTL9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTL9" } ] } ] }, { "uniprot_ac": "A0A8V0YTN5", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTN5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTN5" } ] } ] }, { "uniprot_ac": "A0A8V0YTP2", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTP2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTP2" } ] } ] }, { "uniprot_ac": "A0A8V0YXZ5", "gene_name": "CDC42BPA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YXZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXZ5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YXZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXZ5" } ] } ] }, { "uniprot_ac": "A0A8V0YYX2", "gene_name": "PAK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YYX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYX2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YYX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYX2" } ] } ] }, { "uniprot_ac": "A0A8V0YYZ3", "gene_name": "SPEG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YYZ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYZ3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YYZ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYZ3" } ] } ] }, { "uniprot_ac": "A0A8V0YZ74", "gene_name": "MAP2K5", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZ74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZ74" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V0YZ74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZ74" } ] } ] }, { "uniprot_ac": "A0A8V0YZF2", "gene_name": "PAK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZF2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YZF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZF2" } ] } ] }, { "uniprot_ac": "A0A8V0YZK0", "gene_name": "MAP3K6", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZK0" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0YZK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZK0" } ] } ] }, { "uniprot_ac": "A0A8V0YZM1", "gene_name": "MOK", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZM1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0YZM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZM1" } ] }, { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZM1" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0YZM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZM1" } ] } ] }, { "uniprot_ac": "A0A8V0YZV9", "gene_name": "ATR", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZV9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YZV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZV9" } ] } ] }, { "uniprot_ac": "A0A8V0YZY4", "gene_name": "SBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZY4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YZY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZY4" } ] } ] }, { "uniprot_ac": "A0A8V0Z124", "gene_name": "VRK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z124", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z124" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z124", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z124" } ] } ] }, { "uniprot_ac": "A0A8V0Z157", "gene_name": "MARK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z157", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z157" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z157", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z157" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A8V0Z157", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z157" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z157", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z157" } ] } ] }, { "uniprot_ac": "A0A8V0Z1X0", "gene_name": "MAP4K3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z1X0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1X0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z1X0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1X0" } ] } ] }, { "uniprot_ac": "A0A8V0Z283", "gene_name": "MARK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z283", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z283" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z283", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z283" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A8V0Z283", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z283" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z283", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z283" } ] } ] }, { "uniprot_ac": "A0A8V0Z2E3", "gene_name": "PDIK1L", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z2E3", "database": 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"https://www.uniprot.org/uniprotkb/A0A8V0Z466" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z466", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z466" } ] } ] }, { "uniprot_ac": "A0A8V0Z6K4", "gene_name": "PIK3R4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z6K4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6K4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z6K4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6K4" } ] } ] }, { "uniprot_ac": "A0A8V0Z6T1", "gene_name": "ERN2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z6T1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6T1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z6T1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6T1" } ] } ] }, { "uniprot_ac": "A0A8V0Z807", "gene_name": "NEK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z807", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z807" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z807", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z807" } ] } ] }, { "uniprot_ac": "A0A8V0Z8G2", "gene_name": "TTBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z8G2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8G2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": 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"https://www.uniprot.org/uniprotkb/A0A8V0Z927" } ] } ] }, { "uniprot_ac": "A0A8V0Z930", "gene_name": "CAMK2B", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z930", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z930" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V0Z930", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z930" } ] } ] }, { "uniprot_ac": "A0A8V0Z9J0", "gene_name": "CIT", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z9J0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9J0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z9J0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9J0" } ] } ] }, { 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[ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZB33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB33" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V0ZB33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB33" } ] } ] }, { "uniprot_ac": "A0A8V0ZB38", "gene_name": "CIITA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZB38", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB38" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZB38", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB38" } ] } ] }, { "uniprot_ac": "A0A8V0ZBN6", "gene_name": "MAP2K1", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZBN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBN6" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V0ZBN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBN6" } ] } ] }, { "uniprot_ac": "A0A8V0ZBZ2", "gene_name": "MAP3K9", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZBZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBZ2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0ZBZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBZ2" } ] } ] }, { "uniprot_ac": "A0A8V0ZC16", "gene_name": "KALRN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": 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"id": "A0A8V0ZQJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQJ2" } ] } ] }, { "uniprot_ac": "A0A8V0ZQT5", "gene_name": "SLC13A3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZQT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQT5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZQT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQT5" } ] } ] }, { "uniprot_ac": "A0A8V0ZRX1", "gene_name": "SETD6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZRX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRX1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZRX1", "database": "UniProtKB", "url": 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"id": "A0A8V0ZZE4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZE4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZZE4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZE4" } ] } ] }, { "uniprot_ac": "A0A8V0ZZK5", "gene_name": "STK38", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZZK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZK5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZZK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZK5" } ] } ] }, { "uniprot_ac": "A0A8V0ZZV3", "gene_name": "MYO3B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZZV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZV3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZZV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZV3" } ] } ] }, { "uniprot_ac": "A0A8V1A069", "gene_name": "TESK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A069", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A069" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V1A069", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A069" } ] } ] }, { "uniprot_ac": "A0A8V1A0W4", "gene_name": "ULK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A0W4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0W4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A0W4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0W4" } ] } ] }, { "uniprot_ac": "A0A8V1A0Y8", "gene_name": "MAST2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A0Y8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0Y8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A0Y8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0Y8" } ] } ] }, { "uniprot_ac": "A0A8V1A1P3", "gene_name": "SRPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A1P3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1P3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A1P3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1P3" } ] } ] }, { "uniprot_ac": "A0A8V1A1Y7", "gene_name": "CDK2", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A1Y7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1Y7" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V1A1Y7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1Y7" } ] } ] }, { "uniprot_ac": "A0A8V1A2T9", "gene_name": "MAP3K14", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A2T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2T9" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V1A2T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2T9" } ] } ] }, { "uniprot_ac": "A0A8V1A3T8", "gene_name": "MAST3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A3T8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3T8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A3T8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3T8" } ] } ] }, { "uniprot_ac": "A0A8V1A4A1", "gene_name": "CAMKK2", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4A1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4A1" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V1A4A1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4A1" } ] } ] }, { "uniprot_ac": "A0A8V1A4J8", "gene_name": "MAPKAPK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4J8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4J8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A4J8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4J8" } ] } ] }, { "uniprot_ac": "A0A8V1A4Q4", "gene_name": "MAPK3", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4Q4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4Q4" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V1A4Q4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4Q4" } ] } ] }, { "uniprot_ac": "A0A8V1A4V7", "gene_name": "HIPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4V7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4V7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A4V7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4V7" } ] } ] }, { "uniprot_ac": "A0A8V1A513", "gene_name": "DAPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A513", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A513" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A513", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A513" } ] } ] }, { "uniprot_ac": "A0A8V1A675", "gene_name": "CSNK1G2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A675", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A675" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A675", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A675" } ] } ] }, { "uniprot_ac": "A0A8V1A7E0", "gene_name": "DYRK3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7E0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E0" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V1A7E0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E0" } ] } ] }, { "uniprot_ac": "A0A8V1A7E9", "gene_name": "SIK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7E9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A7E9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E9" } ] } ] }, { "uniprot_ac": "A0A8V1A7M0", "gene_name": "STK39", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7M0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7M0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A7M0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7M0" } ] } ] }, { "uniprot_ac": "A0A8V1A7P9", "gene_name": "DCAF1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A7P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P9" } ] } ] }, { "uniprot_ac": "A0A8V1A9S5", "gene_name": "NUAK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A9S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9S5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A9S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9S5" } ] } ] }, { "uniprot_ac": "A0A8V1ABF3", "gene_name": "PRKAA2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] } ] }, { "uniprot_ac": "A0A8V1ABP4", "gene_name": "DSTYK", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABP4" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V1ABP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABP4" } ] } ] }, { "uniprot_ac": "A0A8V1ABR8", "gene_name": "CAMK4L", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABR8" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V1ABR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABR8" } ] } ] }, { "uniprot_ac": "A0A8V1AC40", "gene_name": "CDK18", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AC40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC40" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V1AC40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC40" } ] } ] }, { "uniprot_ac": "A0A8V1ACB5", "gene_name": "MAPK13", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACB5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V1ACB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACB5" } ] } ] }, { "uniprot_ac": "A0A8V1ACF6", "gene_name": "PIM1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACF6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ACF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACF6" } ] } ] }, { "uniprot_ac": "A0A8V1ACK0", "gene_name": "MAPKAPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACK0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ACK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACK0" } ] } ] }, { "uniprot_ac": "A0A8V1ACW2", "gene_name": "WNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACW2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ACW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACW2" } ] } ] }, { "uniprot_ac": "A0A8V1ADF0", "gene_name": "MAP2K2", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ADF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADF0" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V1ADF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADF0" } ] } ] }, { "uniprot_ac": "A0A8V1ADN9", "gene_name": "NLK", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ADN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADN9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V1ADN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADN9" } ] } ] }, { "uniprot_ac": "A0A8V1ADT4", "gene_name": "MKNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ADT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADT4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ADT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADT4" } ] } ] }, { "uniprot_ac": "A0A8V1AE45", "gene_name": "ERN1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AE45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE45" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AE45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE45" } ] } ] }, { "uniprot_ac": "A0A8V1AEH4", "gene_name": "STK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AEH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEH4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AEH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEH4" } ] } ] }, { "uniprot_ac": "A0A8V1AFS4", "gene_name": "STKLD1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AFS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFS4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AFS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFS4" } ] } ] }, { "uniprot_ac": "A0A8V1AG70", "gene_name": "LOC100857512", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AG70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AG70" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AG70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AG70" } ] } ] }, { "uniprot_ac": "A0A8V1AH12", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AH12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH12" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AH12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH12" } ] } ] }, { "uniprot_ac": "A0A8V1AHA8", "gene_name": "NEK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AHA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHA8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AHA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHA8" } ] } ] }, { "uniprot_ac": "A0A8V1AIY7", "gene_name": "AATK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AIY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIY7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AIY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIY7" } ] } ] }, { "uniprot_ac": "A0A8V1AJA4", "gene_name": "RPS6KB1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AJA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJA4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AJA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJA4" } ] } ] }, { "uniprot_ac": "A0A8V1AKW4", "gene_name": "MAP2K4", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AKW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKW4" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V1AKW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKW4" } ] } ] }, { "uniprot_ac": "A0A8V1AM12", "gene_name": "GSG2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AM12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM12" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AM12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM12" } ] } ] }, { "uniprot_ac": "A0A8V1AMK5", "gene_name": "PRKCA", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AMK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMK5" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V1AMK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMK5" } ] } ] }, { "uniprot_ac": "A0A8V1AMQ2", "gene_name": "CAMKK1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AMQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMQ2" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V1AMQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMQ2" } ] } ] }, { "uniprot_ac": "A0A8V1AP60", "gene_name": "KSR1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AP60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP60" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AP60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP60" } ] } ] }, { "uniprot_ac": "E1BQN6", "gene_name": "PRKCZ", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BQN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQN6" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1BQN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQN6" } ] } ] }, { "uniprot_ac": "E1BQV7", "gene_name": "SLK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BQV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQV7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BQV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQV7" } ] } ] }, { "uniprot_ac": "E1BUG0", "gene_name": "CDK12", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] } ] }, { "uniprot_ac": "E1BW33", "gene_name": "SMG1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BW33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BW33" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BW33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BW33" } ] } ] }, { "uniprot_ac": "E1BWA3", "gene_name": "PRKCI", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BWA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWA3" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1BWA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWA3" } ] } ] }, { "uniprot_ac": "E1BWT0", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BWT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWT0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BWT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWT0" } ] } ] }, { "uniprot_ac": "E1BX69", "gene_name": "EIF2AK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BX69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BX69" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BX69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BX69" } ] } ] }, { "uniprot_ac": "E1BY69", "gene_name": "PIM3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BY69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BY69" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BY69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BY69" } ] } ] }, { "uniprot_ac": "E1BYH2", "gene_name": "TAOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BYH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BYH2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BYH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BYH2" } ] } ] }, { "uniprot_ac": "E1C093", "gene_name": "PIK3CG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.154", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.154", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] } ] }, { "uniprot_ac": "E1C2I2", "gene_name": "MASTL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C2I2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C2I2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C2I2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C2I2" } ] } ] }, { "uniprot_ac": "E1C581", "gene_name": "TBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C581", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C581" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C581", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C581" } ] } ] }, { "uniprot_ac": "E1C6T4", "gene_name": "PRKD3", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C6T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C6T4" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1C6T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C6T4" } ] } ] }, { "uniprot_ac": "E1C764", "gene_name": "BMP2K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C764", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C764" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C764", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C764" } ] } ] }, { "uniprot_ac": "E1C848", "gene_name": "MAP3K8", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C848", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C848" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1C848", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C848" } ] } ] }, { "uniprot_ac": "F1NA68", "gene_name": "CDK3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NA68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NA68" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1NA68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NA68" } ] } ] }, { "uniprot_ac": "F1NB57", "gene_name": "PLK2", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NB57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NB57" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "F1NB57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NB57" } ] } ] }, { "uniprot_ac": "F1NBT0", "gene_name": "STK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NBT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NBT0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1NBT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NBT0" } ] } ] }, { "uniprot_ac": "F1NCX7", "gene_name": "PLK1", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NCX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCX7" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "F1NCX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCX7" } ] } ] }, { "uniprot_ac": "F1NCY7", "gene_name": "MAPKAPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NCY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCY7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1NCY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCY7" } ] } ] }, { "uniprot_ac": "F1NJH1", "gene_name": "PRKCH", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NJH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NJH1" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1NJH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NJH1" } ] } ] }, { "uniprot_ac": "F1NKW3", "gene_name": "MAP3K15", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NKW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NKW3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1NKW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NKW3" } ] } ] }, { "uniprot_ac": "F1NLR7", "gene_name": "CLK3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NLR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NLR7" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "F1NLR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NLR7" } ] } ] }, { "uniprot_ac": "F1NUX4", "gene_name": "MTOR", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NUX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NUX4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1NUX4", "database": "UniProtKB", "url": 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O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P05625", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05625" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P05625", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05625" } ] } ] }, { "uniprot_ac": "P10741", "gene_name": "MOS", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P10741", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P10741" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P10741", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P10741" } ] } ] }, { "uniprot_ac": "P13863", "gene_name": "CDK1", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P13863", "database": "UniProtKB", "url": 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O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P79996", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P79996" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "P79996", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P79996" } ] } ] }, { "uniprot_ac": "Q04982", "gene_name": "BRAF", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q04982", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q04982" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q04982", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q04982" } ] } ] }, { "uniprot_ac": "Q0GGW5", "gene_name": "STK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q0GGW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0GGW5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q0GGW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0GGW5" } ] } ] }, { "uniprot_ac": "Q5F3L1", "gene_name": "RPS6KA5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5F3L1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F3L1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q5F3L1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F3L1" } ] } ] }, { "uniprot_ac": "Q5F3W3", "gene_name": "MAPK6", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5F3W3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F3W3" } ] }, { "ec_number": "2.7.11.24", "activity": "", 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"ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q6U1I9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6U1I9" } ] } ] }, { "uniprot_ac": "Q6XUX0", "gene_name": "DSTYK", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q6XUX0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6XUX0" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "Q6XUX0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6XUX0" } ] } ] }, { "uniprot_ac": "Q7T0B1", "gene_name": "STK40", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q7T0B1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q7T0B1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q7T0B1", "database": "UniProtKB", 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"PRKDC", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q8QGX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8QGX4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8QGX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8QGX4" } ] } ] }, { "uniprot_ac": "Q90771", "gene_name": "CDK6", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q90771", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q90771" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q90771", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q90771" } ] } ] }, { "uniprot_ac": "Q90891", "gene_name": "MAP2K2", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q90891", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q90891" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "Q90891", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q90891" } ] } ] }, { "uniprot_ac": "Q9I9E0", "gene_name": "TAOK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q9I9E0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9I9E0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9I9E0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9I9E0" } ] } ] }, { "uniprot_ac": "Q9IA88", "gene_name": "SIK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q9IA88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9IA88" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9IA88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9IA88" } ] } ] }, { "uniprot_ac": "R4GIN8", "gene_name": "PRKACB", "activity": [ { "ec_number": "2.7.11.11", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "R4GIN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GIN8" } ] }, { "ec_number": "2.7.11.11", "activity": "", "evidence": [ { "id": "R4GIN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GIN8" } ] } ] }, { "uniprot_ac": "R4GJB8", "gene_name": "TESK1", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "R4GJB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GJB8" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "R4GJB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GJB8" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1NE00-1", "uniprot_ac": "F1NE00", "uniprot_id": "F1NE00_CHICK", "mass": { "chemical_mass": 109462.0, "monoisotopic_mass": 109462.0 }, "refseq": { "ac": "NP_001280234", "name": "kinesin heavy chain", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001280234" }, "gene_names": [ { "name": "KIF5C", "type": "recommended", "evidence": [ { "id": "F1NE00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NE00" } ] }, { "name": "KIF5C", "type": "synonym", "evidence": [ { "id": "NP_001280234", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001280234" } ] } ], "protein_names": [ { "name": "Kinesin-like protein", "type": "recommended", "evidence": [ { "id": "F1NE00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NE00/entry#names_and_taxonomy" } ] }, { "name": "kinesin Kif5c", "type": "synonym", "evidence": [ { "id": "NP_001280234", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001280234" } ] }, { "name": "kinesin heavy chain", "type": "synonym", "evidence": [ { "id": "NP_001280234", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001280234" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## inferred exon combination :: based on alignments, homology ##RefSeq-Attributes-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000236.1. On Jun 7, 2014 this sequence version replaced XP_422155.2. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001280234", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001280234" } ] }, { "annotation": "In the chick embryo, kif5c plays a role during different morphogenetic processes.", "evidence": [ { "database": "RefSeq", "id": "NP_001280234", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001280234" }, { "database": "PubMed", "id": "14758548", "url": "https://glygen.org/publication/PubMed/14758548" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NE00", "url": "https://www.uniprot.org/uniprotkb/F1NE00" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "KIF5C", "url": "https://www.uniprot.org/uniprotkb/F1NE00", "locus": { "chromosome": "7", "start_pos": 34451491, "end_pos": 34383938, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010009578", "url": "https://www.ensembl.org/id/ENSGALG00010009578" } ] } } ], "crossref": [ { "id": "F1NE00", "url": "https://alphafold.ebi.ac.uk/entry/F1NE00", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000012462", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000012462", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd01369", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01369", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd23649", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd23649", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "408046", "url": "https://www.ncbi.nlm.nih.gov/gene/408046", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001752", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001752", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019821", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019821", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027640", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027640", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036961", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036961", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR059182", "url": "https://www.ebi.ac.uk/interpro/entry/IPR059182", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:408046", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:408046", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QKSAEPY", "url": "https://omabrowser.org/oma/group/QKSAEPY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y2L6", "url": "https://www.orthodb.org/?gene=A0A8V0Y2L6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NE00", "url": "https://www.orthodb.org/?gene=F1NE00", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47968", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47968", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47968:SF70", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47968:SF70", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00225", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00225", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001280234", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001280234", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Y2L6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2L6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y2L6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2L6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NE00", "url": "https://www.uniprot.org/uniprotkb/F1NE00", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NE00-1", "url": "https://www.uniprot.org/uniprotkb/F1NE00-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MADPAECSIKVMCRFRPLNEAEILRGDKFIPKFKGEETVVIGQGKPYVFDRVLPPNTTQEQVYNACAKQIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPQLMGIIPRIAHDIFDHIYSMDENLEFHIKVSYFEIYLDKIRDLLDVSKTNLAVHEDKNRVPYVKGCTERFVSSPEEVLDVIDEGKANRHVAVTNMNEHSSRSHSIFLINIKQENVETEKKLSGKLYLVDLAGSEKVSKTGAEGAVLDEAKNINKSLSALGNVISALAEGTKTHVPYRDSKMTRILQDSLGGNCRTTIVICCSPSIFNEAETKSTLMFGQRAKTIKNTVSVNLELTAEEWKKKYEKEKDKNKSLKNVIQHLELELNRWRNGEAVPEDEQISAKDQKNLEPCDNTPIIDNITPVVASISTEEKQKYDEEIASLYRQLDDKDDEINQQSQLAEKLKQQMLDQEELLASTRRDYEKIQEELTRLQIENEAAKDEVKEVLQALEELAVNYDQKSQEVEDKTRANEQLADELAQKSTVLSATQRELGQLQELSNHQKKRATEILNLLLKDLGEIGGIIGTNDVKTLADVNGVIEEEFTMARLYISKMKSEVKSLVNRSKQLESAQIDSNRKMNASERELAACQLLISQHEAKIKSLTDYMQNMEQKRRQLEESQDSLNEELAKLRAQEKMHEVSFKDKEKEHLTRLQDAEEMKKALEQQMESHREAHQKQLSRLRDEIEEKQKTIDEIRDMNQKLQLEQEKLSADYDKLKIEDQEREMKLEKLILLNDKREQAREDLKGLEETVARELQTLHNLRKLFVQDLTTRVKKSVELDSDDGGGSAAQKQKISFLENNLEQLTKVHKQLVRDNADLRCELPKLEKRLRATAERVKALESALKEAKENAMRDRKRYQQEVDRIKEAVRAKNMARRAHSAQIAKPIRPGHYPASSPTAVHAIRGGGMSNSSYYHSTK", "length": 957, "header": "tr|F1NE00-1|F1NE00_CHICK Isoform 1 of Kinesin-like protein OS=Gallus gallus OX=9031 GN=KIF5C PE=1 SV=2 CANONICAL=F1NE00-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Y2L6-1", "url": "https://www.uniprot.org/uniprotkb/F1NE00/entry#A0A8V0Y2L6-1", "sequence": { "sequence": "MADPAECSIKVMCRFRPLNEAEILRGDKFIPKFKGEETVVIGQGKPYVFDRVLPPNTTQEQVYNACAKQIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPQLMGIIPRIAHDIFDHIYSMDENLEFHIKVSYFEIYLDKIRDLLDVSKTNLAVHEDKNRVPYVKGCTERFVSSPEEVLDVIDEGKANRHVAVTNMNEHSSRSHSIFLINIKQENVETEKKLSGKLYLVDLAGSEKVSKTGAEGAVLDEAKNINKSLSALGNVISALAEGTKTHVPYRDSKMTRILQDSLGGNCRTTIVICCSPSIFNEAETKSTLMFGQRAKTIKNTVSVNLELTAEEWKKKYEKEKDKNKSLKNVIQHLELELNRWRNGEAVPEDEQISAKDQKNLEPCDNTPIIDNITPVVASISTEEKQKYDEEIASLYRQLDDKDDEINQQSQLAEKLKQQMLDQEELLASTRRDYEKIQEELTRLQIENEAAKDEVKEVLQALEELAVNYDQKSQEVEDKTRANEQLADELAQKSTVLSATQRELGQLQELSNHQKKRATEILNLLLKDLGEIGGIIGTNDVKTLADVNGVIEEEFTMARLYISKMKSEVKSLVNRSKQLESAQIDSNRKMNASERELAACQLLISQHEAKIKSLTDYMQNMEQKRRQLEESQDSLNEELAKLRAQEKMHEVSFKDKEKEHLTRLQDAEEMKKALEQQMESHREAHQKQLSRLRDEIEEKQKTIDEIRDMNQKLQLEQEKLSADYDKLKIEDQEREMKLEKLILLNDKREQAREDLKGLEETVARELQTLHNLRKLFVQDLTTRVKKSVELDSDDGGGSAAQKQKISFLENNLEQLTKVHKQAAQNLTAARSISGMEERSRKLVRDNADLRCELPKLEKRLRATAERVKALESALKEAKENAMRDRKRYQQEVDRIKEAVRAKNMARRAHSAQIAKPIRPGHYPASSPTAVHAIRGGGMSNSSYYHSTK", "length": 977, "header": "tr|A0A8V0Y2L6-1|A0A8V0Y2L6_CHICK Computationally mapped isoform of Kinesin-like protein OS=Gallus gallus OX=9031 GN=KIF5C PE=1 SV=1 CANONICAL=F1NE00-1" }, "locus": { "chromosome": "7", "start_pos": 34442836, "end_pos": 34384022, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010022830.1", "url": "https://www.ensembl.org/id/ENSGALT00010022830.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010013193.1", "url": "https://www.ensembl.org/id/ENSGALP00010013193.1" } ] } }, { "isoform_ac": "F1NE00-1", "url": "https://www.uniprot.org/uniprotkb/F1NE00/entry#F1NE00-1", "sequence": { "sequence": "MADPAECSIKVMCRFRPLNEAEILRGDKFIPKFKGEETVVIGQGKPYVFDRVLPPNTTQEQVYNACAKQIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPQLMGIIPRIAHDIFDHIYSMDENLEFHIKVSYFEIYLDKIRDLLDVSKTNLAVHEDKNRVPYVKGCTERFVSSPEEVLDVIDEGKANRHVAVTNMNEHSSRSHSIFLINIKQENVETEKKLSGKLYLVDLAGSEKVSKTGAEGAVLDEAKNINKSLSALGNVISALAEGTKTHVPYRDSKMTRILQDSLGGNCRTTIVICCSPSIFNEAETKSTLMFGQRAKTIKNTVSVNLELTAEEWKKKYEKEKDKNKSLKNVIQHLELELNRWRNGEAVPEDEQISAKDQKNLEPCDNTPIIDNITPVVASISTEEKQKYDEEIASLYRQLDDKDDEINQQSQLAEKLKQQMLDQEELLASTRRDYEKIQEELTRLQIENEAAKDEVKEVLQALEELAVNYDQKSQEVEDKTRANEQLADELAQKSTVLSATQRELGQLQELSNHQKKRATEILNLLLKDLGEIGGIIGTNDVKTLADVNGVIEEEFTMARLYISKMKSEVKSLVNRSKQLESAQIDSNRKMNASERELAACQLLISQHEAKIKSLTDYMQNMEQKRRQLEESQDSLNEELAKLRAQEKMHEVSFKDKEKEHLTRLQDAEEMKKALEQQMESHREAHQKQLSRLRDEIEEKQKTIDEIRDMNQKLQLEQEKLSADYDKLKIEDQEREMKLEKLILLNDKREQAREDLKGLEETVARELQTLHNLRKLFVQDLTTRVKKSVELDSDDGGGSAAQKQKISFLENNLEQLTKVHKQLVRDNADLRCELPKLEKRLRATAERVKALESALKEAKENAMRDRKRYQQEVDRIKEAVRAKNMARRAHSAQIAKPIRPGHYPASSPTAVHAIRGGGMSNSSYYHSTK", "length": 957, "header": "tr|F1NE00-1|F1NE00_CHICK Isoform 1 of Kinesin-like protein OS=Gallus gallus OX=9031 GN=KIF5C PE=1 SV=2 CANONICAL=F1NE00-1" }, "locus": { "chromosome": "7", "start_pos": 34442836, "end_pos": 34384022, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010022834.1", "url": "https://www.ensembl.org/id/ENSGALT00010022834.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010013196.1", "url": "https://www.ensembl.org/id/ENSGALP00010013196.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Expression of kinesin kif5c during chick development.", "journal": "Anatomy and embryology", "date": "2004-03", "authors": "Dathe V, Pr\u00f6ls F, Brand-Saberi B", "evidence": [ { "database": "RefSeq", "id": "NP_001280234", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001280234" } ], "reference": [ { "type": "PubMed", "id": "14758548", "url": "https://glygen.org/publication/PubMed/14758548" } ] } ], "pathway": [ { "id": "gga:408046", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:408046", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A480PZV2-1", "protein_name": "Kinesin-like protein", "gene_name": "KIF5C", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MADPAECSIKVMCRFRPLNEAEILRGDKFIPKFKGDETVVIGQGKPYVFDRVLPPSTTQEQVYNACAKQIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPQLMGIIPRIAHDIFDHIYSMDENLEFHIKVSYFEIYLDKIRDLLDVSKTNLAVHEDKNRVPYVKGCTERFVSSPEEVMDVIDEGKANRHVAVTNMNEHSSRSHSIFLINIKQENVETEKKLSGKLYLVDLAGSEKVSKTGAEGAVLDEAKNINKSLSALGNVISALAEGTKTHVPYRDSKMTRILQDSLGGNCRTTIVICCSPSVFNEAETKSTLMFGQRAKTIKNTVSVNLELTAEEWKKKYEKEKEKNKTLKNVIQHLEMELNRWRNGEAVPEDEQISAKDQKTLEPCDNTPIIDNIAPVVAGITAEEKEKYDEEISSLYRQLDDKDDEINQQSQLAEKLKQQMLDQDELLASTRRDYEKIQEELTRLQIENEAAKDEVKEVLQALEELAVNYDQKSQEVEDKTRANEQLTDELAQKTTTLTTTQRELSQLQELSNHQKKRATEILNLLLKDLGEIGGIIGTNDVKTLADVNGVIEEEFTMARLYISKMKSEVKSLVNRSKQLESAQMDSNRKMNASERELAACQLLISQHEAKIKSLTDYMQNMEQKRRQLEESQDSLSEELAKLRAQEKMHEVSFQDKEKEHLTRLQDAEEMKKALEQQMESHREAHQKQLSRLRDEIEEKQKIIDEIRDLNQKLQLEQEKLSSDYNKLKIEDQEREMKLEKLLLLNDKREQAREDLKGLEETVSRELQTLHNLRKLFVQDLTARVKKSVELDSDDGGGSAAQKQKISFLENNLEQLTKVHKQLVRDNADLRCELPKLEKRLRATAERVKALESALKEAKENAMRDRKRYQQEVDRIKEAVRAKNMARRAHSAQIAKPIRPGHYPASSPTAVHAIRGGGGGSSNPTHHQK", "length": 957 }, "evidence": [ { "id": "F1NE00", "url": "https://omabrowser.org/oma/group/F1NE00/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "O60282-1", "protein_name": "Kinesin heavy chain isoform 5C", "gene_name": "KIF5C", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MADPAECSIKVMCRFRPLNEAEILRGDKFIPKFKGDETVVIGQGKPYVFDRVLPPNTTQEQVYNACAKQIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPQLMGIIPRIAHDIFDHIYSMDENLEFHIKVSYFEIYLDKIRDLLDVSKTNLAVHEDKNRVPYVKGCTERFVSSPEEVMDVIDEGKANRHVAVTNMNEHSSRSHSIFLINIKQENVETEKKLSGKLYLVDLAGSEKVSKTGAEGAVLDEAKNINKSLSALGNVISALAEGTKTHVPYRDSKMTRILQDSLGGNCRTTIVICCSPSVFNEAETKSTLMFGQRAKTIKNTVSVNLELTAEEWKKKYEKEKEKNKTLKNVIQHLEMELNRWRNGEAVPEDEQISAKDQKNLEPCDNTPIIDNIAPVVAGISTEEKEKYDEEISSLYRQLDDKDDEINQQSQLAEKLKQQMLDQDELLASTRRDYEKIQEELTRLQIENEAAKDEVKEVLQALEELAVNYDQKSQEVEDKTRANEQLTDELAQKTTTLTTTQRELSQLQELSNHQKKRATEILNLLLKDLGEIGGIIGTNDVKTLADVNGVIEEEFTMARLYISKMKSEVKSLVNRSKQLESAQMDSNRKMNASERELAACQLLISQHEAKIKSLTDYMQNMEQKRRQLEESQDSLSEELAKLRAQEKMHEVSFQDKEKEHLTRLQDAEEMKKALEQQMESHREAHQKQLSRLRDEIEEKQKIIDEIRDLNQKLQLEQEKLSSDYNKLKIEDQEREMKLEKLLLLNDKREQAREDLKGLEETVSRELQTLHNLRKLFVQDLTTRVKKSVELDNDDGGGSAAQKQKISFLENNLEQLTKVHKQLVRDNADLRCELPKLEKRLRATAERVKALESALKEAKENAMRDRKRYQQEVDRIKEAVRAKNMARRAHSAQIAKPIRPGHYPASSPTAVHAIRGGGGSSSNSTHYQK", "length": 957 }, "evidence": [ { "id": "F1NE00", "url": "https://omabrowser.org/oma/group/F1NE00/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P28738-1", "protein_name": "Kinesin heavy chain isoform 5C", "gene_name": "Kif5c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MADPAECSIKVMCRFRPLNEAEILRGDKFIPKFKGEETVVIGQGKPYVFDRVLPPNTTQEQVYNACAKQIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPQLMGIIPRIAHDIFDHIYSMDENLEFHIKVSYFEIYLDKIRDLLDVSKTNLAVHEDKNRVPYVKGCTERFVSSPEEVMDVIDEGKANRHVAVTNMNEHSSRSHSIFLINIKQENVETEKKLSGKLYLVDLAGSEKVSKTGAEGAVLDEAKNINKSLSALGNVISALAEGTKTHVPYRDSKMTRILQDSLGGNCRTTIVICCSPSVFNEAETKSTLMFGQRAKTIKNTVSVNLELTAEEWKKKYEKEKEKNKALKSVLQHLEMELNRWRNGEAVPEDEQISAKDQKSLEPCDNTPIIDNITPVVDGISAEKEKYDEEITSLYRQLDDKDDEINQQSQLAEKLKQQMLDQDELLASTRRDYEKIQEELTRLQIENEAAKDEVKEVLQALEELAVNYDQKSQEVEDKTRANEQLTDELAQKTTTLTTTQRELSQLQELSNHQKKRATEILNLLLKDLGEIGGIIGTNDVKTLADVNGVIEEEFTMARLYISKMKSEVKSLVNRSKQLESAQMDSNRKMNASERELAACQLLISQHEAKIKSLTDYMQNMEQKRRQLEESQDSLSEELAKLRAQEKMHEVSFQDKEKEHLTRLQDAEEVKKALEQQMESHREAHQKQLSRLRDEIEEKQRIIDEIRDLNQKLQLEQERLSSDYNKLKIEDQEREVKLEKLLLLNDKREQAREDLKGLEETVSRELQTLHNLRKLFVQDLTTRVKKSVELDSDDGGGSAAQKQKISFLENNLEQLTKVHKQLVRDNADLRCELPKLEKRLRATAERVKALESALKEAKENAMRDRKRYQQEVDRIKEAVRAKNMARRAHSAQIAKPIRPGHYPASSPTAVHAVRGGGGGSSNSTHYQK", "length": 956 }, "evidence": [ { "id": "F1NE00", "url": "https://omabrowser.org/oma/group/F1NE00/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P56536-1", "protein_name": "Kinesin heavy chain isoform 5C", "gene_name": "Kif5c", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MADPAECSIKVMCRFRPLNEAEILRGDKFIPKFKGEETVVIGQGKPYVFDRVLPPNTTQEQVYNACAKQIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPQLMGIIPRIAHDIFDHIYSMDENLEFHIKVSYFEIYLDKIRDLLDVSKTNLAVHEDKNRVPYVKGCTERFVSSPEEVMDVIDEGKANRHVAVTNMNEHSSRSHSIFLINIKQENVETEKKLSGKLYLVDLAGSEKVSKTGAEGAVLDEAKNINKSLSALGNVISALAEGTKTHVPYRDSKMTRILQDSLGGNCRTTIVICCSPSVFNEAETKSTLMFGQRAKTIKNTVSVNLELTAEEWKKKYEKEKEKNKALKSVIQHLEVELNRWRNGEAVPEDEQISAKDQKNLEPCDNTPIIDNITPVVDGISAEKEKYDEEITSLYRQLDDKDDEINQQSQLAEKLKQQMLDQDELLASTRRDYEKIQEELTRLQIENEAAKDEVKEVLQALEELAVNYDQKSQEVEDKTRANEQLTDELAQKTTTLTTTQRELSQLQELSNHQKKRATEILNLLLKDLGEIGGIIGTNDVKTLADVNGVIEEEFTMARLYISKMKSEVKSLVNRSKQLESAQTDSNRKMNASERELAACQLLISQHEAKIKSLTDYMQNMEQKRRQLEESQDSLSEELAKLRAQEKMHEVSFQDKEKEHLTRLQDAEEVKKALEQQMESHREAHQKQLSRLRDEIEEKQRIIDEIRDLNQKLQLEQERLSSDYNKLKIEDQEREVKLEKLLLLNDKREQAREDLKGLEETVSRELQTLHNLRKLFVQDLTTRVKKSVELDSDDGGGSAAQKQKISFLENNLEQLTKVHKQLVRDNADLRCELPKLEKRLRATAERVKALESALKEAKENAMRDRKRYQQEVDRIKEAVRAKNMARRAHSAQIAKPIRPGHYPASSPTAVHAVRGGGGSSNSTHYQK", "length": 955 }, "evidence": [ { "id": "F1NE00", "url": "https://omabrowser.org/oma/group/F1NE00/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "F1NE00", "url": "https://www.uniprot.org/uniprotkb/F1NE00" } ], "pmid": "" }, { "name": "microtubule binding", "id": "GO:0008017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008017", "evidence": [ { "database": "UniProtKB", "id": "F1NE00", "url": "https://www.uniprot.org/uniprotkb/F1NE00" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "F1NE00", "url": "https://www.uniprot.org/uniprotkb/F1NE00" } ], "pmid": "" }, { "name": "plus-end-directed microtubule motor activity", "id": "GO:0008574", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008574", "evidence": [ { "database": "UniProtKB", "id": "F1NE00", "url": "https://www.uniprot.org/uniprotkb/F1NE00" } ], "pmid": "" }, { "name": "microtubule motor activity", "id": "GO:0003777", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003777", "evidence": [ { "database": "UniProtKB", "id": "F1NE00", "url": "https://www.uniprot.org/uniprotkb/F1NE00" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 7, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1NE00", "url": "https://www.uniprot.org/uniprotkb/F1NE00" } ], "pmid": "" }, { "name": "microtubule", "id": "GO:0005874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005874", "evidence": [ { "database": "UniProtKB", "id": "F1NE00", "url": "https://www.uniprot.org/uniprotkb/F1NE00" } ], "pmid": "" }, { "name": "ciliary rootlet", "id": "GO:0035253", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035253", "evidence": [ { "database": "UniProtKB", "id": "F1NE00", "url": "https://www.uniprot.org/uniprotkb/F1NE00" } ], "pmid": "" }, { "name": "neuronal cell body", "id": "GO:0043025", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043025", "evidence": [ { "database": "UniProtKB", "id": "F1NE00", "url": "https://www.uniprot.org/uniprotkb/F1NE00" } ], "pmid": "" }, { "name": "kinesin complex", "id": "GO:0005871", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005871", "evidence": [ { "database": "UniProtKB", "id": "F1NE00", "url": "https://www.uniprot.org/uniprotkb/F1NE00" } ], "pmid": "" }, { "name": "dendrite cytoplasm", "id": "GO:0032839", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032839", "evidence": [ { "database": "UniProtKB", "id": "F1NE00", "url": "https://www.uniprot.org/uniprotkb/F1NE00" } ], "pmid": "" }, { "name": "axonal growth cone", "id": "GO:0044295", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044295", "evidence": [ { "database": "UniProtKB", "id": "F1NE00", "url": "https://www.uniprot.org/uniprotkb/F1NE00" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "axon guidance", "id": "GO:0007411", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007411", "evidence": [ { "database": "UniProtKB", "id": "F1NE00", "url": "https://www.uniprot.org/uniprotkb/F1NE00" } ], "pmid": "" }, { "name": "anterograde dendritic transport of neurotransmitter receptor complex", "id": "GO:0098971", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098971", "evidence": [ { "database": "UniProtKB", "id": "F1NE00", "url": "https://www.uniprot.org/uniprotkb/F1NE00" } ], "pmid": "" }, { "name": "mRNA transport", "id": "GO:0051028", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051028", "evidence": [ { "database": "UniProtKB", "id": "F1NE00", "url": "https://www.uniprot.org/uniprotkb/F1NE00" } ], "pmid": "" }, { "name": "synaptic vesicle transport", "id": "GO:0048489", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048489", "evidence": [ { "database": "UniProtKB", "id": "F1NE00", "url": "https://www.uniprot.org/uniprotkb/F1NE00" } ], "pmid": "" }, { "name": "anterograde dendritic transport of messenger ribonucleoprotein complex", "id": "GO:0098964", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098964", "evidence": [ { "database": "UniProtKB", "id": "F1NE00", "url": "https://www.uniprot.org/uniprotkb/F1NE00" } ], "pmid": "" }, { "name": "microtubule-based movement", "id": "GO:0007018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007018", "evidence": [ { "database": "UniProtKB", "id": "F1NE00", "url": "https://www.uniprot.org/uniprotkb/F1NE00" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 256, "end_pos": 258, "annotation": "n_glycosylation_sequon" }, { "start_pos": 353, "end_pos": 355, "annotation": "n_glycosylation_sequon" }, { "start_pos": 401, "end_pos": 403, "annotation": "n_glycosylation_sequon" }, { "start_pos": 56, "end_pos": 58, "annotation": "n_glycosylation_sequon" }, { "start_pos": 603, "end_pos": 605, "annotation": "n_glycosylation_sequon" }, { "start_pos": 620, "end_pos": 622, "annotation": "n_glycosylation_sequon" }, { "start_pos": 79, "end_pos": 81, "annotation": "n_glycosylation_sequon" }, { "start_pos": 949, "end_pos": 951, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 256, "end_pos": 258 }, { "start_pos": 353, "end_pos": 355 }, { "start_pos": 401, "end_pos": 403 }, { "start_pos": 56, "end_pos": 58 }, { "start_pos": 603, "end_pos": 605 }, { "start_pos": 620, "end_pos": 622 }, { "start_pos": 79, "end_pos": 81 }, { "start_pos": 949, "end_pos": 951 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "E1C494-1", "uniprot_ac": "E1C494", "uniprot_id": "E1C494_CHICK", "mass": { "chemical_mass": 20197.0, "monoisotopic_mass": 20197.0 }, "refseq": { "ac": "NP_001264418", "name": "60S ribosome subunit biogenesis protein NIP7 homolog", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264418" }, "gene_names": [ { "name": "NIP7", "type": "recommended", "evidence": [ { "id": "E1C494", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C494" } ] }, { "name": "CGI-37", "type": "synonym", "evidence": [ { "id": "NP_001264418", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264418" } ] }, { "name": "HSPC031", "type": "synonym", "evidence": [ { "id": "NP_001264418", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264418" } ] }, { "name": "KD93", "type": "synonym", "evidence": [ { "id": "NP_001264418", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264418" } ] }, { "name": "NIP7", "type": "synonym", "evidence": [ { "id": "NP_001264418", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264418" } ] } ], "protein_names": [ { "name": "60S ribosome subunit biogenesis protein NIP7 homolog", "type": "recommended", "evidence": [ { "id": "E1C494", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C494/entry#names_and_taxonomy" } ] }, { "name": "60S ribosome subunit biogenesis protein NIP7 homolog", "type": "synonym", "evidence": [ { "id": "NP_001264418", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264418" } ] }, { "name": "nuclear import 7 homolog", "type": "synonym", "evidence": [ { "id": "NP_001264418", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264418" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: BU471242.1, BU404125.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000248.1. On Apr 10, 2013 this sequence version replaced XP_414222.1. Sequence Note: This record was constructed from sequences from the Leghorn strain instead of the reference (Red Jungle Fowl) strain.", "evidence": [ { "database": "RefSeq", "id": "NP_001264418", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264418" } ] }, { "annotation": "Required for proper 34S pre-rRNA processing and 60S ribosome subunit assembly.", "evidence": [ { "database": "UniProtKB", "id": "E1C494", "url": "https://www.uniprot.org/uniprotkb/E1C494#function" }, { "database": "UniProtKB", "id": "ARBA00004087", "url": "https://www.uniprot.org/uniprotkb/ARBA00004087#function" }, { "database": "UniProtKB", "id": "PIRNR017190", "url": "https://www.uniprot.org/uniprotkb/PIRNR017190#function" }, { "database": "UniProtKB", "id": "A0A8V0Y567", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y567#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1C494", "url": "https://www.uniprot.org/uniprotkb/E1C494" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "NIP7", "url": "https://www.uniprot.org/uniprotkb/E1C494", "locus": { "chromosome": "11", "start_pos": 18581991, "end_pos": 18580409, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010008219", "url": "https://www.ensembl.org/id/ENSGALG00010008219" } ] } } ], "crossref": [ { "id": "E1C494", "url": "https://alphafold.ebi.ac.uk/entry/E1C494", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000000650", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000000650", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd21146", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd21146", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd21151", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd21151", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "415863", "url": "https://www.ncbi.nlm.nih.gov/gene/415863", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002478", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002478", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005155", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005155", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015947", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015947", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016686", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016686", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036974", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036974", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040598", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040598", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055359", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055359", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:415863", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:415863", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "LISMGTC", "url": "https://omabrowser.org/oma/group/LISMGTC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y567", "url": "https://www.orthodb.org/?gene=A0A8V0Y567", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1C494", "url": "https://www.orthodb.org/?gene=E1C494", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23415", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23415", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03657", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03657", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17833", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17833", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001264418", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264418", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Y567", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y567", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y567-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y567-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C494", "url": "https://www.uniprot.org/uniprotkb/E1C494", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C494-1", "url": "https://www.uniprot.org/uniprotkb/E1C494-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRPLTEAETRAVFEKLGRYIGENIQLLVDRPDGTYCFRLHRDRVYYVSEKLLKGAASIPRDSLVALGTCFGKFTKTQKFRLSVTALDFLAPYAKYKVWVKPGSEQSFLYGNHVLKSGLGRITENTAQYQGVVVYSMADVPLGFGVAAKSTQDCRKVDPMAIVVFHQADVGEYVRNEDTLT", "length": 180, "header": "tr|E1C494-1|E1C494_CHICK Isoform 1 of 60S ribosome subunit biogenesis protein NIP7 homolog OS=Gallus gallus OX=9031 GN=NIP7 PE=1 SV=3 CANONICAL=E1C494-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Y567-1", "url": "https://www.uniprot.org/uniprotkb/E1C494/entry#A0A8V0Y567-1", "sequence": { "sequence": "RGGGRKTRGHWGNTEDGSDVVFPCSIGENIQLLVDRPDGTYCFRLHRDRVYYVSEKLLKGAASIPRDSLVALGTCFGKFTKTQKFRLSVTALDFLAPYAKYKVWVKPGSEQSFLYGNHVLKSGLGRITENTAQYQGVVVYSMADVPLGFGVAAKSTQDCRKVDPMAIVVFHQADVGEYVRNEDTLT", "length": 186, "header": "tr|A0A8V0Y567-1|A0A8V0Y567_CHICK Computationally mapped isoform of 60S ribosome subunit biogenesis protein NIP7 homolog OS=Gallus gallus OX=9031 GN=NIP7 PE=1 SV=1 CANONICAL=E1C494-1" }, "locus": { "chromosome": "11", "start_pos": 18581577, "end_pos": 18580762, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010019652.1", "url": "https://www.ensembl.org/id/ENSGALT00010019652.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010011200.1", "url": "https://www.ensembl.org/id/ENSGALP00010011200.1" } ] } }, { "isoform_ac": "E1C494-1", "url": "https://www.uniprot.org/uniprotkb/E1C494/entry#E1C494-1", "sequence": { "sequence": "MRPLTEAETRAVFEKLGRYIGENIQLLVDRPDGTYCFRLHRDRVYYVSEKLLKGAASIPRDSLVALGTCFGKFTKTQKFRLSVTALDFLAPYAKYKVWVKPGSEQSFLYGNHVLKSGLGRITENTAQYQGVVVYSMADVPLGFGVAAKSTQDCRKVDPMAIVVFHQADVGEYVRNEDTLT", "length": 180, "header": "tr|E1C494-1|E1C494_CHICK Isoform 1 of 60S ribosome subunit biogenesis protein NIP7 homolog OS=Gallus gallus OX=9031 GN=NIP7 PE=1 SV=3 CANONICAL=E1C494-1" }, "locus": { "chromosome": "11", "start_pos": 18581577, "end_pos": 18580457, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010019654.1", "url": "https://www.ensembl.org/id/ENSGALT00010019654.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010011202.1", "url": "https://www.ensembl.org/id/ENSGALP00010011202.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:415863", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:415863", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2LLW7-1", "protein_name": "60S ribosome subunit biogenesis protein NIP7 homolog", "gene_name": "Nip7", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MRPLTEEETRVMFEKIAKYIGENLQLLVDRPDGTYCFRLHNDRVYYVSEMILKLAANISGDKLVSLGTCFGKFTKTHKFRLHVTALDYLAPYAKYKVWIKPGAEQSFLYGNHVLKSGLGRITENTSQYQGVVVYSMADVPLGFGVAAKSTQDCRKVDPMAIVVFHQADIGEYVRHEETLT", "length": 180 }, "evidence": [ { "id": "E1C494", "url": "https://omabrowser.org/oma/group/E1C494/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "B0G104-1", "protein_name": "60S ribosome subunit biogenesis protein NIP7 homolog", "gene_name": "nip7", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MRPMTEEESKTFFEKLIKFIGKNVTLLIQRKDEPYCFRIQKNKVYYVSEELMKRSQNIPREGLCSLGTCFGRFTKTGKFKLNITCLDYLAQYAKYKVWVKPSSEMSWMYGNNLLKAGLGRITEDTPANQGVVLFSMNDVPIGFGVTSKSTHECRKLDPQALVVYHYGDVGEYLRDEDIM", "length": 179 }, "evidence": [ { "id": "E1C494", "url": "https://omabrowser.org/oma/group/E1C494/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q08962-1", "protein_name": "60S ribosome subunit biogenesis protein NIP7", "gene_name": "NIP7", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MRQLTEEETKVVFEKLAGYIGRNISFLVDNKELPHVFRLQKDRVYYVPDHVAKLATSVARPNLMSLGICLGKFTKTGKFRLHITSLTVLAKHAKYKIWIKPNGEMPFLYGNHVLKAHVGKMSDDIPEHAGVIVFAMNDVPLGFGVSAKSTSESRNMQPTGIVAFRQADIGEYLRDEDTLFT", "length": 181 }, "evidence": [ { "id": "E1C494", "url": "https://omabrowser.org/oma/group/E1C494/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q503P2-1", "protein_name": "60S ribosome subunit biogenesis protein NIP7 homolog", "gene_name": "nip7", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MRPLTDEETKTMFEKLSKYIGENIKLLIDRPDGTYCFRLHNDRVYYMSEKILKLATNVSRDKLVSVGTCFGKFTKTQKFRLHITALDFLAPYAKFKVWVKPGSEQSFLYGNHIMKSGLGRITENTDKYQGVLVYSMADVPLGFGVAARTTQECRKVDPMAIVVFHQADIGEYIRSEDTLT", "length": 180 }, "evidence": [ { "id": "E1C494", "url": "https://omabrowser.org/oma/group/E1C494/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q56P27-1", "protein_name": "60S ribosome subunit biogenesis protein NIP7 homolog", "gene_name": "NIP7", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRPLTEEETRVMFEKIAKYIGENLQLLVDRPDGTYCFRLHNDRVYYVSEKILKLAANISGDKLMSLGTCFGKFTKTHKFRLHITALDYLAPYAKYKVWIKPGAEQSFLYGNHVLKSGLGRITENTSQYQGVVVYSMADIPLGFGVAAKSTQDCRKVDPMAIVVFHQADIGEYVRHEETLT", "length": 180 }, "evidence": [ { "id": "E1C494", "url": "https://omabrowser.org/oma/group/E1C494/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q9CXK8-1", "protein_name": "60S ribosome subunit biogenesis protein NIP7 homolog", "gene_name": "Nip7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRPLTEEETRVMFEKIAKYIGENLQLLVDRPDGTYCFRLHNDRVYYVSEMMLKLAANISGDKLVSLGTCFGKFTKTHKFRLHVTALDYLAPYAKYKVWVKPGAEQSFLYGNHVLKSGLGRITENTSQYQGVVVYSMADIPLGFGVAAKSTQDCRKVDPMAIVVFHQADIGEYVRHEETLT", "length": 180 }, "evidence": [ { "id": "E1C494", "url": "https://omabrowser.org/oma/group/E1C494/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VC28-1", "protein_name": "60S ribosome subunit biogenesis protein NIP7 homolog", "gene_name": "anon-WO0118547.410", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MKRLSDERAKILFEHLSKYIGTNVKHLIDRPDGTYCFREHKDRVYYVSERILKLSECFGYKQLVCVGTCFGKFSKTNKLKFHITALYYLAPYAQYKVWVKPSFEQQFLYGNHIPKTGLGRITENAGQYQGVVVYSMNDLPLGFGVLARSTTDCKTADPMTTVCFHQSDIGEYIRAEDTLF", "length": 180 }, "evidence": [ { "id": "E1C494", "url": "https://omabrowser.org/oma/group/E1C494/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9WV50-1", "protein_name": "60S ribosome subunit biogenesis protein NIP7 homolog", "gene_name": "Nip7", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRPLTEEETRVMFEKIAKYIGENLQLLVDRPDGTYCFRLHNDRVYYVSEMILKLAANISGDKLVSLGTCFGKFTKTHKFRLHVTALDFLAPYAKYKVWIKPGAEQSFLYGNHVLKSGLGRITENTSQYQGVVVYSMADVPLGFGVAAKSTQDCRKVDPMAIVVFHQADIGEYIRHEETLT", "length": 180 }, "evidence": [ { "id": "E1C494", "url": "https://omabrowser.org/oma/group/E1C494/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9Y221-1", "protein_name": "60S ribosome subunit biogenesis protein NIP7 homolog", "gene_name": "NIP7", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRPLTEEETRVMFEKIAKYIGENLQLLVDRPDGTYCFRLHNDRVYYVSEKIMKLAANISGDKLVSLGTCFGKFTKTHKFRLHVTALDYLAPYAKYKVWIKPGAEQSFLYGNHVLKSGLGRITENTSQYQGVVVYSMADIPLGFGVAAKSTQDCRKVDPMAIVVFHQADIGEYVRHEETLT", "length": 180 }, "evidence": [ { "id": "E1C494", "url": "https://omabrowser.org/oma/group/E1C494/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "E1C494", "url": "https://www.uniprot.org/uniprotkb/E1C494" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "E1C494", "url": "https://www.uniprot.org/uniprotkb/E1C494" } ], "pmid": "" }, { "name": "preribosome, large subunit precursor", "id": "GO:0030687", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030687", "evidence": [ { "database": "UniProtKB", "id": "E1C494", "url": "https://www.uniprot.org/uniprotkb/E1C494" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "ribosomal large subunit biogenesis", "id": "GO:0042273", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042273", "evidence": [ { "database": "UniProtKB", "id": "E1C494", "url": "https://www.uniprot.org/uniprotkb/E1C494" } ], "pmid": "" }, { "name": "ribosome assembly", "id": "GO:0042255", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042255", "evidence": [ { "database": "UniProtKB", "id": "E1C494", "url": "https://www.uniprot.org/uniprotkb/E1C494" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BZ03-1", "uniprot_ac": "E1BZ03", "uniprot_id": "E1BZ03_CHICK", "mass": { "chemical_mass": 53197.0, "monoisotopic_mass": 53197.0 }, "refseq": { "ac": "NP_001376435", "name": "adenylyl cyclase-associated protein 2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376435" }, "gene_names": [ { "name": "CAP2", "type": "recommended", "evidence": [ { "id": "E1BZ03", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BZ03" } ] }, { "name": "CAP2", "type": "synonym", "evidence": [ { "id": "NP_001376435", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376435" } ] } ], "protein_names": [ { "name": "Adenylyl cyclase-associated protein", "type": "recommended", "evidence": [ { "id": "E1BZ03", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BZ03/entry#names_and_taxonomy" } ] }, { "name": "CAP, adenylate cyclase-associated protein, 2", "type": "synonym", "evidence": [ { "id": "NP_001376435", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376435" } ] }, { "name": "adenylyl cyclase-associated protein 2", "type": "synonym", "evidence": [ { "id": "NP_001376435", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376435" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: SRR13267649.41090.1, SRR13267655.46104.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000040.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001376435", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376435" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1BZ03", "url": "https://www.uniprot.org/uniprotkb/E1BZ03" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CAP2", "url": "https://www.uniprot.org/uniprotkb/E1BZ03", "locus": { "chromosome": "2", "start_pos": 61758860, "end_pos": 61694731, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012730", "url": "https://www.ensembl.org/id/ENSGALG00010012730" } ] } } ], "crossref": [ { "id": "E1BZ03", "url": "https://alphafold.ebi.ac.uk/entry/E1BZ03", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000012715", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000012715", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "420847", "url": "https://www.ncbi.nlm.nih.gov/gene/420847", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001837", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001837", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013912", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013912", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013992", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013992", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016098", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016098", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017901", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017901", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018106", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018106", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036222", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036222", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036223", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036223", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR053950", "url": "https://www.ebi.ac.uk/interpro/entry/IPR053950", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:420847", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420847", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PISDHIH", "url": "https://omabrowser.org/oma/group/PISDHIH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YFL6", "url": "https://www.orthodb.org/?gene=A0A8V0YFL6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YGM6", "url": "https://www.orthodb.org/?gene=A0A8V0YGM6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1BZ03", "url": "https://www.orthodb.org/?gene=E1BZ03", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10652", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10652", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10652:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10652:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01213", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01213", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08603", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08603", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21938", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21938", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001376435", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376435", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YFL6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFL6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YFL6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFL6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YGM6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGM6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YGM6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGM6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BZ03", "url": "https://www.uniprot.org/uniprotkb/E1BZ03", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BZ03-1", "url": "https://www.uniprot.org/uniprotkb/E1BZ03-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAENHGLMERLEKAVTRLESLFSDSQRSGGMECDAMNGVNGSIAPYVEAFDRLLNGSVAEFLRYSKILEGDVKTHAEMVRAAFQAQRSFLVLASQCQEPQENEVAVLLKPISEKIQEIQNFRERNRGSKMFNHLSAVSESIPALGWIAVSPKPGPYVKEMNDAATFYTNRVLKDYKHSDTRHVDWVKSYLNIWSELQAYIKEHHTTGLTWSKTGPVASPTSMRSVLTSGSCLSSPPPPPPPPPGPPPIFDTETPPKDEGTASRSALFAQLNQGEAITKGLRHVSDDQKTHKNPSLRAQGPPARSPTKSHTPSPTSPKNSPQQSHAPVLELEGKKWRVEYQEDKNDLVITNTELKQVAYIFKCNKSTLQIKGKINSITIDNCKKFGLVFDNVVGIVEVINSRDIQIQVMGKVPTISINKTEGCHIYLSEESLDCEIVSAKSSEMNILIPQDGDYKEFPVPEQFKTAWDGSKLVTEPAEIVG", "length": 480, "header": "tr|E1BZ03-1|E1BZ03_CHICK Isoform 1 of Adenylyl cyclase-associated protein OS=Gallus gallus OX=9031 GN=CAP2 PE=1 SV=1 CANONICAL=E1BZ03-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YFL6-1", "url": "https://www.uniprot.org/uniprotkb/E1BZ03/entry#A0A8V0YFL6-1", "sequence": { "sequence": "MIFYHRITESLELEGTSEGHLVQLPFNEQGHPLLDQIAQGQIRMAENHGLMERLEKAVTRLESLFSDSQRSGGMECDAMNGVNGSIAPYVEAFDRLLNGSVAEFLRYSKILEGDVKTHAEMVRAAFQAQRSFLVLASQCQEPQENEVAVLLKPISEKIQEIQNFRERNRGSKMFNHLSAVSESIPALGWIAVSPKPGPYVKEMNDAATFYTNRVLKDYKHSDTRHVDWVKSYLNIWSELQAYIKEHHTTGLTWSKTGPVASPTSMRSVLTSGSCLSSPPPPPPPPPGPPPIFDTETPPKDEGTASRSALFAQLNQGEAITKGLRHVSDDQKTHKNPSLRAQGPPARSPTKSHTPSPTSPKNSPQQSHAPVLELEGKKWRVEYQEDKNDLVITNTELKQVAYIFKCNKSTLQIKGKINSITIDNCKKFGLVFDNVVGIVEVINSRDIQIQVMGKVPTISINKTEGCHIYLSEESLDCEIVSAKSSEMNILIPQDGDYKEFPVPEQFKTAWDGSKLVTEPAEIVG", "length": 523, "header": "tr|A0A8V0YFL6-1|A0A8V0YFL6_CHICK Computationally mapped isoform of Adenylyl cyclase-associated protein OS=Gallus gallus OX=9031 GN=CAP2 PE=1 SV=1 CANONICAL=E1BZ03-1" }, "locus": { "chromosome": "2", "start_pos": 61757318, "end_pos": 61694930, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030475.1", "url": "https://www.ensembl.org/id/ENSGALT00010030475.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017678.1", "url": "https://www.ensembl.org/id/ENSGALP00010017678.1" } ] } }, { "isoform_ac": "A0A8V0YGM6-1", "url": "https://www.uniprot.org/uniprotkb/E1BZ03/entry#A0A8V0YGM6-1", "sequence": { "sequence": "MRMAENHGLMERLEKAVTRLESLFSDSQRSGGMECDAMNGVNGSIAPYVEAFDRLLNGSVAEFLRYSKILEGDVKTHAEMVRAAFQAQRSFLVLASQCQEPQENEVAVLLKPISEKIQEIQNFRERNRGSKMFNHLSAVSESIPALGWIAVSPKPGPYVKEMNDAATFYTNRVLKDYKHSDTRHVDWVKSYLNIWSELQAYIKEHHTTGLTWSKTGPVASPTSMRSVLTSGSCLSSPPPPPPPPPGPPPIFDTETPPKDEGTASRSALFAQLNQGEAITKGLRHVSDDQKTHKNPSLRAQGPPARSPTKSHTPSPTSPKNSPQQSHAPVLELEGKKWRVEYQEDKNDLVITNTELKQVAYIFKCNKSTLQIKGKINSITIDNCKKFGLVFDNVVGIVEVINSRDIQIQVMGKVPTISINKTEGCHIYLSEESLDCEIVSAKSSEMNILIPQDGDYKEFPVPEQFKTAWDGSKLVTEPAEIVG", "length": 482, "header": "tr|A0A8V0YGM6-1|A0A8V0YGM6_CHICK Computationally mapped isoform of Adenylyl cyclase-associated protein OS=Gallus gallus OX=9031 GN=CAP2 PE=1 SV=1 CANONICAL=E1BZ03-1" }, "locus": { "chromosome": "2", "start_pos": 61757318, "end_pos": 61702733, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030473.1", "url": "https://www.ensembl.org/id/ENSGALT00010030473.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017676.1", "url": "https://www.ensembl.org/id/ENSGALP00010017676.1" } ] } }, { "isoform_ac": "E1BZ03-1", "url": "https://www.uniprot.org/uniprotkb/E1BZ03/entry#E1BZ03-1", "sequence": { "sequence": "MAENHGLMERLEKAVTRLESLFSDSQRSGGMECDAMNGVNGSIAPYVEAFDRLLNGSVAEFLRYSKILEGDVKTHAEMVRAAFQAQRSFLVLASQCQEPQENEVAVLLKPISEKIQEIQNFRERNRGSKMFNHLSAVSESIPALGWIAVSPKPGPYVKEMNDAATFYTNRVLKDYKHSDTRHVDWVKSYLNIWSELQAYIKEHHTTGLTWSKTGPVASPTSMRSVLTSGSCLSSPPPPPPPPPGPPPIFDTETPPKDEGTASRSALFAQLNQGEAITKGLRHVSDDQKTHKNPSLRAQGPPARSPTKSHTPSPTSPKNSPQQSHAPVLELEGKKWRVEYQEDKNDLVITNTELKQVAYIFKCNKSTLQIKGKINSITIDNCKKFGLVFDNVVGIVEVINSRDIQIQVMGKVPTISINKTEGCHIYLSEESLDCEIVSAKSSEMNILIPQDGDYKEFPVPEQFKTAWDGSKLVTEPAEIVG", "length": 480, "header": "tr|E1BZ03-1|E1BZ03_CHICK Isoform 1 of Adenylyl cyclase-associated protein OS=Gallus gallus OX=9031 GN=CAP2 PE=1 SV=1 CANONICAL=E1BZ03-1" }, "locus": { "chromosome": "2", "start_pos": 61757318, "end_pos": 61703452, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030471.1", "url": "https://www.ensembl.org/id/ENSGALT00010030471.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017675.1", "url": "https://www.ensembl.org/id/ENSGALP00010017675.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 314, "start_aa": "Thr", "end_pos": 314, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr314", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:420847", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420847", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0R4IXA9-1", "protein_name": "Adenylyl cyclase-associated protein", "gene_name": "cap2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEALVGRLERAVVRLEAVAVKLQSCPGGLINGDISAVINGGESQSMEAFDRLLSGSVSEYVQSSAAIGGDVAKHAEMVNNALQVQRTLLKMAMTHQEPAKTELADLLRPLSDQIQAVQNFREKNRGSSLFNHLSAVSESIPALGWVAVCQKPGPYVKEMNDAAMFYTNRVLKDFKDTDARHVEWVRSYLSIWTDLQTFIREHHCTGLIWSKTGPKAPPSLLSAPLLPPPPPPPPPMMIDSCSSPADASSVQHAALFAQLNQGEEITKGLKHVCDEQKTHKNPNLRSQSGKTHHDSPSKTQSSSSSNPARKHPPVLELEGKKWRVEYQDQCAELLIEDTELRQVVYVFSCSGSTLQVKGKVNSIIVDNCKKLGLVFDNVVGIVEIINSRDIQLQVMGKVPTISINKTEGCHVYLSKDSLDCEIVSAKSSEMNILVPEGEDDYREFPVPEQFKTVWDGSSLVTEPTKIAG", "length": 468 }, "evidence": [ { "id": "E1BZ03", "url": "https://omabrowser.org/oma/group/E1BZ03/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8C2MYE4-1", "protein_name": "Adenylyl cyclase-associated protein", "gene_name": "Cap2", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MADMLGLVERLECAVNRLEQLSAGPCGPPGDCGEVNGVNGGVAPSVEAFDKLVNSMVAEFLKKSRVLSGDVETHAEMVHSAFQAQRAFLLMASQYQQPQENEVAVLLKPISEKIQEIQTFRERNRGSSMFNHLSAVSESIPALGWIAVSPKPGPYVKEMNDAATFYTNRVLKDYKHSDLRHVDWVKSYLNIWSQLQAYIKEHHTTGLTWSKTGPVASTASVFSVFSSGPGLPPPPPPPPPPGPPPLFENEGKNEESSPSRSALFAQLNQGEAITKGLRHVTDDQKIYKNPSLRAQGQTRSPTKTYTPSPTSPKSNSPQKHAPVLELEGKKWRVEYHEDKNDLVISETELKQVAYIFKCEKSTLQIKGKINSITVDNCKKFGLVFDNVVGIVEVINSKDIQIQVIGRVPTISINKTEGCHLYLSEDALDCEIVSAKSSEMNVLIPQGDDYREFPIPEQFKTVWDGSKLVTEPAEIMA", "length": 476 }, "evidence": [ { "id": "E1BZ03", "url": "https://omabrowser.org/oma/group/E1BZ03/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0AAA9T3I1-1", "protein_name": "Adenylyl cyclase-associated protein", "gene_name": "CAP2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAEMQGLMERLERAVGRLELLSAGSHRPPGDCGEINGVNGGVAPSVEAFDKLMNSMVAEFLKKSRILAGDVETHAEMVHSAFQAQRAFLLMASQYQQPQENDVAALLKPISEKIQEIQTFRERNRGSTMFNHLSAVSESIPALGWIAVSPKPGPYVKEMNDAATFYTNRVLKDYKHSDLRHVDWVKSYLNIWSELQAYIKEHHTTGLTWSKTGPVASTASALSVLSLGPGLPPPPPPPPPPGPPLLFESEGIKEPSSPSRSALFAQLNQGEAITKGLRHVTDDQKTYKNPNLRAHGGQSPSPTKSHTPGPKSPQSHPSKKHTPVLELEGKKWRVEYQEDRNDLVISETALRQVAYIFKCGKSTLQIKGKINSIIIDNCKKFGLVFDNVVGIVEVINSKDIQMQVMGKVPTISINKTEGCHIYLSEDALDCEIVSAKSSEMNILIPQDGDYREFPVPEQFKTAWDGAKLITEPTEIMVSERPPKPLT", "length": 486 }, "evidence": [ { "id": "E1BZ03", "url": "https://omabrowser.org/oma/group/E1BZ03/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1RUJ0-1", "protein_name": "Adenylyl cyclase-associated protein", "gene_name": "CAP2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAEMQGLMERLERAVGRLELLSAGSHQPPGDCGGINGVNGGVAPSVEAFDKLMNGMVAEFLKKSRILAGDVETHAEMVHSAFQAQRAFLLMASQYQQPQENDVAALLKPISEKIQEIQTFRERNRGSKMFNHLSAVSESIPALGWIAVSPKPGPYVKEMNDAATFYTNRVLKDYKHSDLRHVDWVKSYLNIWSELQAYIKEHHTTGLTWSKTGPVASTASALSVLSLGPGLPPPPPPPPPPGPPPLFESEGRREEPSPSRSALFAQLNQGEAITRGLRHVTDDQKTYKNPSLRAPGGQTPSPTKSHSPGPKSPHSHPPKKHAPMLELEGKKWRIEYQEDRNDLVISETELRQVAYIFKCNKSTLQIKGKINSIIVDNCKKFGLVFDNAVGIVEVINSKDIQMQVMGKVPTISINKTEGCHIYLSEDALDCDIVSAKSSEMNILIPRDGDYREFPVPEQFKTAWDGSKLVTEPTEIMVSERPPKPLN", "length": 486 }, "evidence": [ { "id": "E1BZ03", "url": "https://omabrowser.org/oma/group/E1BZ03/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P40123-1", "protein_name": "Adenylyl cyclase-associated protein 2", "gene_name": "CAP2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MANMQGLVERLERAVSRLESLSAESHRPPGNCGEVNGVIAGVAPSVEAFDKLMDSMVAEFLKNSRILAGDVETHAEMVHSAFQAQRAFLLMASQYQQPHENDVAALLKPISEKIQEIQTFRERNRGSNMFNHLSAVSESIPALGWIAVSPKPGPYVKEMNDAATFYTNRVLKDYKHSDLRHVDWVKSYLNIWSELQAYIKEHHTTGLTWSKTGPVASTVSAFSVLSSGPGLPPPPPPLPPPGPPPLFENEGKKEESSPSRSALFAQLNQGEAITKGLRHVTDDQKTYKNPSLRAQGGQTQSPTKSHTPSPTSPKSYPSQKHAPVLELEGKKWRVEYQEDRNDLVISETELKQVAYIFKCEKSTIQIKGKVNSIIIDNCKKLGLVFDNVVGIVEVINSQDIQIQVMGRVPTISINKTEGCHIYLSEDALDCEIVSAKSSEMNILIPQDGDYREFPIPEQFKTAWDGSKLITEPAEIMA", "length": 477 }, "evidence": [ { "id": "E1BZ03", "url": "https://omabrowser.org/oma/group/E1BZ03/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P52481-1", "protein_name": "Adenylyl cyclase-associated protein 2", "gene_name": "Cap2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MADMLGLMQRLEFAVSRLERLSSGLHEPPGGCGEVNSLSRGIVAPSVEAFDKLINSMVAEFLKNSRVLAGDVETHAEMVHGAFQAQRAFLLMVSQHQQPQENEVAVLLKPISEKIQEIQTFRERNRGSDMFNHLSAVSESIAALGWIAVSPKPGPYVKEMNDAATFYTNRVLRDYKHSDLRHVDWVRSYLKIWSELQAYIKEHHTTGLTWSKTGPVASTASAFSILSSGPGLPPPPPPPPPPGPPPPFENEGGKEEPSPSRSALFAQLNQGEAITKGLRHVTDDKKIYKNPSLRAQGQIRSPTKTRTPSPTSSKSNSPQKHAPVLELEGKKWRVEYQEDRNDLVISETELKQVAYIFKCDKSTLQIKGKVNSITVDNCKKFGLVFDHVVGIVEVINSKDIQIQVMGRVPTISINKTEGCHLYLSKDALDCEIVSAKSSEMNVLVPQGDDYREFPIPEQFKTIWDGSKLITEPAEIMA", "length": 477 }, "evidence": [ { "id": "E1BZ03", "url": "https://omabrowser.org/oma/group/E1BZ03/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9CYT6-1", "protein_name": "Adenylyl cyclase-associated protein 2", "gene_name": "Cap2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTDMAGLMERLERAVIRLEQLSAGLDGPPRGCGEVNGVNGGVAPSVEAFDKLINSMVAEFLKNSRVLAGDVETHAEMVHGAFQAQRAFLLMVSQYQQPQENEVAVLLKPISEKIQEIQTFRERNRGSNMFNHLSAVSESIAALGWIAVSPKPGPYVKEMNDAATFYTNRVLKDYKHSDLRHVDWVRSYLNIWSELQAYIREHHTTGLTWSKTGPVASTASAFSILSSGPGLPPPPPPPPPPGPPPPFENEDKKEEPSPSRSALFAQLNQGEAITKGLRHVTDDKKTYKNPSLRAQGQIRSPTKTHTPSPTSPKSNSPQKHTPVLELEGKKWRVEYQEDRNDLVISETELKQVAYIFKCDKSTLQIKGKVNSITVDNCKKFGLVFDHVVGIVEVINSKDIQIQVMGRVPTISINKTEGCHLYLSEDALDCEIVSAKSSEMNVLVPQDDDYREFPIPEQFKTIWDGSKLVTEPAEIMA", "length": 476 }, "evidence": [ { "id": "E1BZ03", "url": "https://omabrowser.org/oma/group/E1BZ03/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "actin binding", "id": "GO:0003779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003779", "evidence": [ { "database": "UniProtKB", "id": "E1BZ03", "url": "https://www.uniprot.org/uniprotkb/E1BZ03" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "E1BZ03", "url": "https://www.uniprot.org/uniprotkb/E1BZ03" } ], "pmid": "" }, { "name": "adenylate cyclase binding", "id": "GO:0008179", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008179", "evidence": [ { "database": "UniProtKB", "id": "E1BZ03", "url": "https://www.uniprot.org/uniprotkb/E1BZ03" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "E1BZ03", "url": "https://www.uniprot.org/uniprotkb/E1BZ03" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "E1BZ03", "url": "https://www.uniprot.org/uniprotkb/E1BZ03" } ], "pmid": "" }, { "name": "postsynaptic density", "id": "GO:0014069", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0014069", "evidence": [ { "database": "UniProtKB", "id": "E1BZ03", "url": "https://www.uniprot.org/uniprotkb/E1BZ03" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "actin filament organization", "id": "GO:0007015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007015", "evidence": [ { "database": "UniProtKB", "id": "E1BZ03", "url": "https://www.uniprot.org/uniprotkb/E1BZ03" } ], "pmid": "" }, { "name": "cell morphogenesis", "id": "GO:0000902", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000902", "evidence": [ { "database": "UniProtKB", "id": "E1BZ03", "url": "https://www.uniprot.org/uniprotkb/E1BZ03" } ], "pmid": "" }, { "name": "presynaptic actin cytoskeleton organization", "id": "GO:0099140", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099140", "evidence": [ { "database": "UniProtKB", "id": "E1BZ03", "url": "https://www.uniprot.org/uniprotkb/E1BZ03" } ], "pmid": "" }, { "name": "cytoskeleton organization", "id": "GO:0007010", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007010", "evidence": [ { "database": "UniProtKB", "id": "E1BZ03", "url": "https://www.uniprot.org/uniprotkb/E1BZ03" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 363, "end_pos": 365, "annotation": "n_glycosylation_sequon" }, { "start_pos": 40, "end_pos": 42, "annotation": "n_glycosylation_sequon" }, { "start_pos": 417, "end_pos": 419, "annotation": "n_glycosylation_sequon" }, { "start_pos": 55, "end_pos": 57, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 314 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 363, "end_pos": 365 }, { "start_pos": 40, "end_pos": 42 }, { "start_pos": 417, "end_pos": 419 }, { "start_pos": 55, "end_pos": 57 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": 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"uniprot_ac": "E1C7J8", "uniprot_id": "E1C7J8_CHICK", "mass": { "chemical_mass": 27532.0, "monoisotopic_mass": 27532.0 }, "refseq": { "ac": "NP_001186483", "name": "mitochondrial inner membrane protease ATP23 homolog", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186483" }, "gene_names": [ { "name": "ATP23", "type": "recommended", "evidence": [ { "id": "E1C7J8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C7J8" } ] }, { "name": "ATP23", "type": "synonym", "evidence": [ { "id": "NP_001186483", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186483" } ] }, { "name": "XRCC6BP1", "type": "synonym", "evidence": [ { "id": "NP_001186483", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186483" } ] } ], "protein_names": [ { "name": "Mitochondrial inner membrane protease ATP23", "type": "recommended", "evidence": [ { "id": "E1C7J8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C7J8/entry#names_and_taxonomy" } ] }, { "name": "3.4.24.-", "type": "synonym", "evidence": [ { "id": "E1C7J8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C7J8/entry#names_and_taxonomy" } ] }, { "name": "XRCC6 binding protein 1", "type": "synonym", "evidence": [ { "id": "NP_001186483", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186483" } ] }, { "name": "mitochondrial inner membrane protease ATP23 homolog", "type": "synonym", "evidence": [ { "id": "NP_001186483", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186483" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: HAEL01000742.1, CR352492.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000012.1. On Dec 10, 2010 this sequence version replaced XP_416054.1. Sequence Note: This RefSeq record was created from transcripts from different strains and genomic sequence data because no single transcript from the same strain was available for the full length of the gene. The extent of this transcript is supported by transcript alignments and orthologous data.", "evidence": [ { "database": "RefSeq", "id": "NP_001186483", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186483" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1C7J8", "url": "https://www.uniprot.org/uniprotkb/E1C7J8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ATP23", "url": "https://www.uniprot.org/uniprotkb/E1C7J8", "locus": { "chromosome": "1", "start_pos": 31594432, "end_pos": 31583963, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010014151", "url": "https://www.ensembl.org/id/ENSGALG00010014151" } ] } } ], "crossref": [ { "id": "E1C7J8", "url": "https://alphafold.ebi.ac.uk/entry/E1C7J8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000009747", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000009747", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "417812", "url": "https://www.ncbi.nlm.nih.gov/gene/417812", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR019165", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019165", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:417812", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417812", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YGJ4", "url": "https://www.orthodb.org/?gene=A0A8V0YGJ4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1C7J8", "url": "https://www.orthodb.org/?gene=E1C7J8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21711", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21711", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21711:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21711:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF09768", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09768", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001186483", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186483", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YGJ4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGJ4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YGJ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGJ4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C7J8", "url": "https://www.uniprot.org/uniprotkb/E1C7J8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C7J8-1", "url": "https://www.uniprot.org/uniprotkb/E1C7J8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEDGKTASPPGAEGGEEEDDFGYRLFPDRNKEPQSFLVRSLFTFHNRCQVMLRMTLETNPYAQLLIAAMKQSGCTVFNDRHFSCENCDGCVSGGFDSATSQIVLCQNNIRHQSHMNRVVAHELIHAFDHCRAHVDWFKNVKHLACSEIRAANLSGDCTLMNEIARFKFGLKGHHQTCVRDRAIRSILAVRKVSRETAEKAVDEVFDACFNDLEPFGRIPHSKTDAKRAYKDFLNRDRYTANL", "length": 242, "header": "tr|E1C7J8-1|E1C7J8_CHICK Isoform 1 of Mitochondrial inner membrane protease ATP23 OS=Gallus gallus OX=9031 GN=ATP23 PE=1 SV=1 CANONICAL=E1C7J8-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YGJ4-1", "url": "https://www.uniprot.org/uniprotkb/E1C7J8/entry#A0A8V0YGJ4-1", "sequence": { "sequence": "MEDGKTASPPGAEGGEEEDDFGYRLFPDRNKEPQSFLVRSLFTFHNRCQVMLRMTLETNPYAQLLIAAMKQSGWYVNYFILCSNIFIVGDQQSFSSSSQTLFVPFSTVFNDRHFSCENCDGCVSGGFDSATSQIVLCQNNIRHQSHMNRVVAHELIHAFDHCRAHVDWFKNVKHLACSEIRAANLSGDCTLMNEIARFKFGLKGHHQTCVRDRAIRSILAVRKVSRETAEKAVDEVFDACFNDLEPFGRIPHSKTDAKRAYKDFLNRDRYTANL", "length": 274, "header": "tr|A0A8V0YGJ4-1|A0A8V0YGJ4_CHICK Computationally mapped isoform of Mitochondrial inner membrane protease ATP23 OS=Gallus gallus OX=9031 GN=ATP23 PE=1 SV=1 CANONICAL=E1C7J8-1" }, "locus": { "chromosome": "1", "start_pos": 31590861, "end_pos": 31584008, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034000.1", "url": "https://www.ensembl.org/id/ENSGALT00010034000.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019984.1", "url": "https://www.ensembl.org/id/ENSGALP00010019984.1" } ] } }, { "isoform_ac": "E1C7J8-1", "url": "https://www.uniprot.org/uniprotkb/E1C7J8/entry#E1C7J8-1", "sequence": { "sequence": "MEDGKTASPPGAEGGEEEDDFGYRLFPDRNKEPQSFLVRSLFTFHNRCQVMLRMTLETNPYAQLLIAAMKQSGCTVFNDRHFSCENCDGCVSGGFDSATSQIVLCQNNIRHQSHMNRVVAHELIHAFDHCRAHVDWFKNVKHLACSEIRAANLSGDCTLMNEIARFKFGLKGHHQTCVRDRAIRSILAVRKVSRETAEKAVDEVFDACFNDLEPFGRIPHSKTDAKRAYKDFLNRDRYTANL", "length": 242, "header": "tr|E1C7J8-1|E1C7J8_CHICK Isoform 1 of Mitochondrial inner membrane protease ATP23 OS=Gallus gallus OX=9031 GN=ATP23 PE=1 SV=1 CANONICAL=E1C7J8-1" }, "locus": { "chromosome": "1", "start_pos": 31590861, "end_pos": 31584008, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034003.1", "url": "https://www.ensembl.org/id/ENSGALT00010034003.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019986.1", "url": "https://www.ensembl.org/id/ENSGALP00010019986.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "gga:417812", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417812", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "metalloendopeptidase activity", "id": "GO:0004222", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004222", "evidence": [ { "database": "UniProtKB", "id": "E1C7J8", "url": "https://www.uniprot.org/uniprotkb/E1C7J8" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "E1C7J8", "url": "https://www.uniprot.org/uniprotkb/E1C7J8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "E1C7J8", "url": "https://www.uniprot.org/uniprotkb/E1C7J8" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "E1C7J8", "url": "https://www.uniprot.org/uniprotkb/E1C7J8" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "E1C7J8", "url": "https://www.uniprot.org/uniprotkb/E1C7J8" } ], "pmid": "" }, { "name": "cell junction", "id": 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}, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1P182-1", "uniprot_ac": "F1P182", "uniprot_id": "F1P182_CHICK", "mass": { "chemical_mass": 57065.0, "monoisotopic_mass": 57065.0 }, "refseq": { "ac": "XP_015147165", "name": "major facilitator superfamily domain-containing protein 1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015147165" }, "gene_names": [ { "name": "MFSD1", "type": "recommended", "evidence": [ { "id": "F1P182", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P182" } ] }, { "name": "MFSD1", "type": "synonym", "evidence": [ { "id": "XP_015147165", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015147165" } ] } ], "protein_names": [ { "name": "Lysosomal dipeptide transporter MFSD1", "type": "recommended", "evidence": [ { "id": "F1P182", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P182/entry#names_and_taxonomy" } ] }, { "name": "Major facilitator superfamily domain-containing protein 1", "type": "synonym", "evidence": [ { "id": "F1P182", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P182/entry#names_and_taxonomy" } ] }, { "name": "major facilitator superfamily domain-containing protein 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015147165", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015147165" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052540.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015147165", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015147165" } ] }, { "annotation": "Lysosomal dipeptide uniporter that selectively exports lysine, arginine or histidine-containing dipeptides with a net positive charge from the lysosome lumen into the cytosol. Could play a role in a specific type of protein O-glycosylation indirectly regulating macrophages migration and tissue invasion. Also essential for liver homeostasis.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0X1H2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X1H2#function" }, { "database": "UniProtKB", "id": "ARBA00045709", "url": "https://www.uniprot.org/uniprotkb/ARBA00045709#function" }, { "database": "UniProtKB", "id": "A0A8V0X4G7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X4G7#function" }, { "database": "UniProtKB", "id": "A0A8V0X761", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X761#function" }, { "database": "UniProtKB", "id": "F1P182", "url": "https://www.uniprot.org/uniprotkb/F1P182#function" }, { "database": "UniProtKB", "id": "A0A8V0X9T3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X9T3#function" }, { "database": "UniProtKB", "id": "A0A8V0X9T8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X9T8#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1P182", "url": "https://www.uniprot.org/uniprotkb/F1P182" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MFSD1", "url": "https://www.uniprot.org/uniprotkb/F1P182", "locus": { "chromosome": "9", "start_pos": 22116914, "end_pos": 22128985, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010001181", "url": "https://www.ensembl.org/id/ENSGALG00010001181" } ] } } ], "crossref": [ { "id": "F1P182", "url": "https://alphafold.ebi.ac.uk/entry/F1P182", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000009593", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000009593", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd17340", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd17340", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "425017", "url": "https://www.ncbi.nlm.nih.gov/gene/425017", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011701", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011701", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020846", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020846", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036259", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036259", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052187", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052187", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "CVLYYSA", "url": "https://omabrowser.org/oma/group/CVLYYSA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0X1H2", "url": "https://www.orthodb.org/?gene=A0A8V0X1H2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0X4G7", "url": "https://www.orthodb.org/?gene=A0A8V0X4G7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0X761", "url": "https://www.orthodb.org/?gene=A0A8V0X761", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0X9T3", "url": "https://www.orthodb.org/?gene=A0A8V0X9T3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0X9T8", "url": "https://www.orthodb.org/?gene=A0A8V0X9T8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1P182", "url": "https://www.orthodb.org/?gene=F1P182", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23512", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23512", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23512:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23512:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07690", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07690", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015147165", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015147165", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "79367", "url": "https://www.rhea-db.org/rhea/79367", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "79371", "url": "https://www.rhea-db.org/rhea/79371", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "79375", "url": "https://www.rhea-db.org/rhea/79375", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "79379", "url": "https://www.rhea-db.org/rhea/79379", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "79383", "url": "https://www.rhea-db.org/rhea/79383", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "79387", "url": "https://www.rhea-db.org/rhea/79387", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "79391", "url": "https://www.rhea-db.org/rhea/79391", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "79395", "url": "https://www.rhea-db.org/rhea/79395", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "79399", "url": "https://www.rhea-db.org/rhea/79399", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "79403", "url": "https://www.rhea-db.org/rhea/79403", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "79407", "url": "https://www.rhea-db.org/rhea/79407", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "79411", "url": "https://www.rhea-db.org/rhea/79411", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "79415", "url": "https://www.rhea-db.org/rhea/79415", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0X1H2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X1H2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0X1H2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X1H2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0X4G7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X4G7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0X4G7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X4G7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0X761", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X761", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0X761-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X761-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0X9T3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X9T3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0X9T3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X9T3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0X9T8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X9T8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0X9T8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X9T8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1P182", "url": "https://www.uniprot.org/uniprotkb/F1P182", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1P182-1", "url": "https://www.uniprot.org/uniprotkb/F1P182-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAEEERALLGPDGGDGGSAAPPRALPAVCDPSRLPHRLLVLALMCFLGFGSCFCYDNPAALQTQVQGDMKVNTARFMALYAWYSWPNVVLCFFGGFLIDRVFGIRLGTVIFSIFVCVGQVIFALGALVNAFWLMEVGRFIFGIGGESLAVAQNTYAVSWFKGKELNLVFGLQLSMARIGSTVNMNIMGWIYSRVQDLLGHTGHATLGLTLLIGGITCLFSLACALILAYLDKRAEKLLCKEQGKTGEVIKLTDVKNFSLSLWLIFVICVCYYAAVFPFIGLGKVFFIEKFQFSSQEASAINSVVYIISAPMSPVFGILVDKVGKNIIWVLCAVITTLASHIMLAFTFWNPWIAMCLLGVAYSLLACALWPMVAFVVPEHQLGTAYGFMQSIQNLGLAVIAIAAGMILDTRGYLFLEVFFSACVSLSLVAVVMLYFVNHLTGGDLNWSAKKREKLQKVAANEAEEQERLRRQNEDDLAKLQPKDDDFSLRNKYLSRLGAQLPDNYSSYLSTMAHRSVLK", "length": 518, "header": "tr|F1P182-1|F1P182_CHICK Isoform 1 of Lysosomal dipeptide transporter MFSD1 OS=Gallus gallus OX=9031 GN=MFSD1 PE=3 SV=3 CANONICAL=F1P182-1" }, "isoforms": [ { "isoform_ac": "A0A8V0X1H2-1", "url": "https://www.uniprot.org/uniprotkb/F1P182/entry#A0A8V0X1H2-1", "sequence": { "sequence": "MAEEERALLGPDGGDGGSAAPPRALPAVCDPSRLPHRLLVLALMCFLGFGSCFCYDNPAALQTQVQGDMKVNTARFMALYAWYSWPNVVLCFFGGFLIDRVFGIRLGTVIFSIFVCVGQVIFALGALVNAFWLMEVGRFIFGIGGESLAVAQNTYAVSWFKGKELNLVFGLQLSMARIGSTVNMNIMGWIYSRVQDLLGHTGHATLGLTLLIGGITCLFSLACALILAYLDKRAEKLLCKEQGKTGEVIKLTDVKNFSLSLWLIFVICVCYYAAVFPFIGLGKVFFIEKFQFSSQEASAINSVVYIISAPMSPVFGILVDKVGKNIIWVLCAVITTLASHIMLAFTFWNPWIAMCLLGVAYSLLACALWPMVAFVVPEHQLGTAYGFMQSIQNLGLAVIAIAAGMILDTRGYLFLEVFFSACVSLSLVAVVMLYFVNHLTGGDLNWSAKKREKLQKVAANEKEI", "length": 464, "header": "tr|A0A8V0X1H2-1|F1P182_CHICK Computationally mapped isoform of Lysosomal dipeptide transporter MFSD1 OS=Gallus gallus OX=9031 GN=MFSD1 PE=3 SV=1 CANONICAL=F1P182-1" }, "locus": { "chromosome": "9", "start_pos": 22128933, "end_pos": 22119846, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010002732.1", "url": "https://www.ensembl.org/id/ENSGALT00010002732.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010001282.1", "url": "https://www.ensembl.org/id/ENSGALP00010001282.1" } ] } }, { "isoform_ac": "A0A8V0X4G7-1", "url": "https://www.uniprot.org/uniprotkb/F1P182/entry#A0A8V0X4G7-1", "sequence": { "sequence": "MKVNTARFMALYAWYSWPNVVLCFFGGFLIDRVFGIRLGTVIFSIFVCVGQVIFALGALVNAFWLMEVGRFIFGIGGESLAVAQNTYAVSWFKGKELNLVFGLQLSMARIGSTVNMNIMGWIYSRVQDLLGHTGHATLGLTLLIGGITCLFSLACALILAYLDKRAEKLLCKEQGKTGEVIKLTDVKNFSLSLWLIFVICVCYYAAVFPFIGLGKVFFIEKFQFSSQEASAINSVVYIISAPMSPVFGILVDKVGKNIIWVLCAVITTLASHIMLAFTFWNPWIAMCLLGVAYSLLACALWPMVAFVVPEHQLGTAYGFMQSIQNLGLAVIAIAAGMILDTRGYLFLEVFFSACVSLSLVAVVMLYFVNHLTGGDLNWSAKKREKLQKVAANEAEEQERLRRQNEDDLAKLQPKDDDFSLRNKYLSRLGAQLPDNYSSYLSTMAHRSVLK", "length": 450, "header": "tr|A0A8V0X4G7-1|F1P182_CHICK Computationally mapped isoform of Lysosomal dipeptide transporter MFSD1 OS=Gallus gallus OX=9031 GN=MFSD1 PE=3 SV=1 CANONICAL=F1P182-1" }, "locus": { "chromosome": "9", "start_pos": 22128208, "end_pos": 22118430, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010002731.1", "url": "https://www.ensembl.org/id/ENSGALT00010002731.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010001281.1", "url": "https://www.ensembl.org/id/ENSGALP00010001281.1" } ] } }, { "isoform_ac": "A0A8V0X761-1", "url": "https://www.uniprot.org/uniprotkb/F1P182/entry#A0A8V0X761-1", "sequence": { "sequence": "MAAPRPPPAPCPPCVTRAASRTACSSSRSCASSASDMKVNTARFMALYAWYSWPNVVLCFFGGFLIDRVFGIRLGTVIFSIFVCVGQVIFALGALVNAFWLMEVGRFIFGIGGESLAVAQNTYAVSWFKGKELNLVFGLQLSMARIGSTVNMNIMGWIYSRVQDLLGHTGHATLGLTLLIGGITCLFSLACALILAYLDKRAEKLLCKEQGKTGEVIKLTDVKNFSLSLWLIFVICVCYYAAVFPFIGLGKVFFIEKFQFSSQEASAINSVVYIISAPMSPVFGILVDKVGKNIIWVLCAVITTLASHIMLAFTFWNPWIAMCLLGVAYSLLACALWPMVAFVVPEHQLGTAYGFMQSIQNLGLAVIAIAAGMILDTRGYLFLEVFFSACVSLSLVAVVMLYFVNHLTGGDLNWSAKKREKLQKVAANEKEI", "length": 432, "header": "tr|A0A8V0X761-1|F1P182_CHICK Computationally mapped isoform of Lysosomal dipeptide transporter MFSD1 OS=Gallus gallus OX=9031 GN=MFSD1 PE=3 SV=1 CANONICAL=F1P182-1" }, "locus": { "chromosome": "9", "start_pos": 22128890, "end_pos": 22119846, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010002729.1", "url": "https://www.ensembl.org/id/ENSGALT00010002729.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010001279.1", "url": "https://www.ensembl.org/id/ENSGALP00010001279.1" } ] } }, { "isoform_ac": "A0A8V0X9T3-1", "url": "https://www.uniprot.org/uniprotkb/F1P182/entry#A0A8V0X9T3-1", "sequence": { "sequence": "MAEEERALLGPDGGDGGSAAPPRALPAVCDPSRLPHRLLVLALMCFLGFAASATTTRRRSRRRFRGLGTVIFSIFVCVGQVIFALGALVNAFWLMEVGRFIFGIGGESLAVAQNTYAVSWFKGKELNLVFGLQLSMARIGSTVNMNIMGWIYSRVQDLLGHTGHATLGLTLLIGGITCLFSLACALILAYLDKRAEKLLCKEQGKTGEVIKLTDVKNFSLSLWLIFVICVCYYAAVFPFIGLGKVFFIEKFQFSSQEASAINSVVYIISAPMSPVFGILVDKVGKNIIWVLCAVITTLASHIMLAFTFWNPWIAMCLLGVAYSLLACALWPMVAFVVPEHQLGTAYGFMQSIQNLGLAVIAIAAGMILDTRGYLFLEVFFSACVSLSLVAVVMLYFVNHLTGGDLNWSAKKREKLQKVAANEKEI", "length": 425, "header": "tr|A0A8V0X9T3-1|A0A8V0X9T3_CHICK Computationally mapped isoform of Lysosomal dipeptide transporter MFSD1 OS=Gallus gallus OX=9031 GN=MFSD1 PE=3 SV=1 CANONICAL=F1P182-1" }, "locus": { "chromosome": "9", "start_pos": 22128933, "end_pos": 22119846, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010002730.1", "url": "https://www.ensembl.org/id/ENSGALT00010002730.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010001280.1", "url": "https://www.ensembl.org/id/ENSGALP00010001280.1" } ] } }, { "isoform_ac": "A0A8V0X9T8-1", "url": "https://www.uniprot.org/uniprotkb/F1P182/entry#A0A8V0X9T8-1", "sequence": { "sequence": "MAEEERALLGPDGGDGGSAAPPRALPAVCDPSRLPHRLLVLALMCFLGFGSCFCYDNPAALQTQVQGVSRCPGVRAWAGSGVIFALGALVNAFWLMEVGRFIFGIGGESLAVAQNTYAVSWFKGKELNLVFGLQLSMARIGSTVNMNIMGWIYSRVQDLLGHTGHATLGLTLLIGGITCLFSLACALILAYLDKRAEKLLCKEQGKTGEVIKLTDVKNFSLSLWLIFVICVCYYAAVFPFIGLGKVFFIEKFQFSSQEASAINSVVYIISAPMSPVFGILVDKVGKNIIWVLCAVITTLASHIMLAFTFWNPWIAMCLLGVAYSLLACALWPMVAFVVPEHQLGTAYGFMQSIQNLGLAVIAIAAGMILDTRGYLFLEVFFSACVSLSLVAVVMLYFVNHLTGGDLNWSAKKREKLQKVAANE", "length": 423, "header": "tr|A0A8V0X9T8-1|A0A8V0X9T8_CHICK Computationally mapped isoform of Lysosomal dipeptide transporter MFSD1 OS=Gallus gallus OX=9031 GN=MFSD1 PE=3 SV=1 CANONICAL=F1P182-1" }, "locus": { "chromosome": "9", "start_pos": 22128933, "end_pos": 22120794, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010002728.1", "url": "https://www.ensembl.org/id/ENSGALT00010002728.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010001278.1", "url": "https://www.ensembl.org/id/ENSGALP00010001278.1" } ] } }, { "isoform_ac": "F1P182-1", "url": "https://www.uniprot.org/uniprotkb/F1P182/entry#F1P182-1", "sequence": { "sequence": "MAEEERALLGPDGGDGGSAAPPRALPAVCDPSRLPHRLLVLALMCFLGFGSCFCYDNPAALQTQVQGDMKVNTARFMALYAWYSWPNVVLCFFGGFLIDRVFGIRLGTVIFSIFVCVGQVIFALGALVNAFWLMEVGRFIFGIGGESLAVAQNTYAVSWFKGKELNLVFGLQLSMARIGSTVNMNIMGWIYSRVQDLLGHTGHATLGLTLLIGGITCLFSLACALILAYLDKRAEKLLCKEQGKTGEVIKLTDVKNFSLSLWLIFVICVCYYAAVFPFIGLGKVFFIEKFQFSSQEASAINSVVYIISAPMSPVFGILVDKVGKNIIWVLCAVITTLASHIMLAFTFWNPWIAMCLLGVAYSLLACALWPMVAFVVPEHQLGTAYGFMQSIQNLGLAVIAIAAGMILDTRGYLFLEVFFSACVSLSLVAVVMLYFVNHLTGGDLNWSAKKREKLQKVAANEAEEQERLRRQNEDDLAKLQPKDDDFSLRNKYLSRLGAQLPDNYSSYLSTMAHRSVLK", "length": 518, "header": "tr|F1P182-1|F1P182_CHICK Isoform 1 of Lysosomal dipeptide transporter MFSD1 OS=Gallus gallus OX=9031 GN=MFSD1 PE=3 SV=3 CANONICAL=F1P182-1" }, "locus": { "chromosome": "9", "start_pos": 22128933, "end_pos": 22118430, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010002733.1", "url": "https://www.ensembl.org/id/ENSGALT00010002733.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010001283.1", "url": "https://www.ensembl.org/id/ENSGALP00010001283.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "D3ZV75-1", "protein_name": "Lysosomal dipeptide transporter MFSD1", "gene_name": "Mfsd1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEEEDGEERALLGGRPEADSALQGAPRALPALCDPSHLAHRLVVLLLMCLLGFGSYFCYDNPGALQTQVKRDMQVNTTKFMLLYAWYSWPNVILCFLGGFLIDRIFGIRWGTVIFSCFVCIGQVIFALGGIFNAFWLMELGRFVFGIGGESLAVAQNTYAVSWFKGKELNLVFGLQLSMARIGSTVNMNLMGWLYGKIEASLGSAGHTTLGVTLMVGGITCILSLICALVLAYLDRRAEKILNKEQGKTGEVIKLTDIKDFSLPLMLVFIICVCYYVAVFPFIGLGKVFFIEKFRFSSQSASAINSIVYIISAPMSPIFGFLVDKTGKNIVWVLCAVATTLVAHMMLAFTFWNPWIAMCLLGFSYSLLACALWPMVAFIVPEHQLGTAYGFMQSIQNLGLAVIAILAGMILDTRGYLLLEVFFIACVSLSLLAVVFLYLVNRARGGNLNYSAKQREQMKPSHSE", "length": 464 }, "evidence": [ { "id": "F1P182", "url": "https://omabrowser.org/oma/group/F1P182/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3I516-1", "protein_name": "Lysosomal dipeptide transporter MFSD1", "gene_name": "Mfsd1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MEEEDEEARGLLGDRPEGDNAVPGAPRALPALCDPSHLAHRLVVLFLMCLLGFGSYFCYDSPAALQTQVKQDMQVNTTKFMLLYAWYSWPNVVLCFLGGFLIDRIFGIRWGTVIFSCFVCIGQAIFALGGIFNAFWLMELGRFVFGIGGESLAVAQNTYAVSWFKGKELNLVFGLQLSMARIGSTVNMNLMGWLYTKIEASLRSPGHMILGVTLMIGCVTCILSLFCALVLAYLDRRAEKILHKEQGKTGDVIKLTDVKDFSLPLWLVFIICVCYYVAIFPFIGLGKVFFMEKFGFASQSASAINSVVYVISAPMSPVFGLLVDKTGKNIIWVLCAVATTLVSHMMLAFTFWNPWIAMCLLGLSYSLLACALWPMVAFVVPEHQLGTAYGFMQSIQNLGLAVISILAGMILDTRGYLFLEVFFIACVSLSLLAVVCLYVVNRARGGNLNYSAKQREELKLSHSE", "length": 464 }, "evidence": [ { "id": "F1P182", "url": "https://omabrowser.org/oma/group/F1P182/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "I3LIQ5-1", "protein_name": "Lysosomal dipeptide transporter MFSD1", "gene_name": "MFSD1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEEEDEEARALLPSSPVKAGRGASNTPDAPRALSALCDPSHLAHRLLVLLLMCFLGFGSYFCYDNPAALQTQVKRDMQVNTTKFMLLYAWYSWPNVILCFFGGFLTDRVFGIRWGTIIFSCFVCIGQVIFALGGIFNAFWLMELGRFVFGIGGESLAVAQNTYAVSWFKGKELNLVFGLQLSMARIGSTVNMNLMGWLYSKVEASLGSAGHTTLGVTLLIGGITCILSLVCALALAYLDQRAERILHKEQGKTGEVIKLTDVKDFSLPLWLIFIICVCYYVAVFPFIGLGKVFFTEKFGFSSQAASAINSIVYVISAPMSPIFGLLVDKTGKNIIWVLCAVVTTLASHMLLAFTLWNPWIAMCLLGLSYSLLACALWPMVAFVVPEHQLGTAYGFMQSIQNLGLAVISIIAGMILDTRGYLFLEVFFIACVSLSLLSVVLLYLVNRAQGGTLNYSATQREEIKLSHAE", "length": 468 }, "evidence": [ { "id": "F1P182", "url": "https://omabrowser.org/oma/group/F1P182/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q1JQC1-1", "protein_name": "Lysosomal dipeptide transporter MFSD1", "gene_name": "MFSD1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MEDEEEEARALLPGGSDEAGRETRAPPAASGALQALCDPSHLAHRLVVLLLMCFLGFGSYFCYDNPAALQIQVKRDMQVNTTKFMLLYAWYSWPNVVLCFFGGFLIDRVFGIRWGTIIFSCFVCIGQVVFALGGIFNAFWLMELGRFVFGIGGESLAVAQNTYAVSWFKGKELNLVFGLQLSMARIGSTVNMNLMGWLYSKVEASLGSAGHTTLGVTLMIGGITCILSLVCALALAYLDQRAERILHKEQGKTGEVIKLTDVKDFSLPLWLIFIICVCYYVAIFPFIGLVKVFFTEKFGFSSQAASAINSVVYVISAPMSPIFGLLVDKTGKNIIWVLCAVVTTLASHIMLAFTLWNPWIAMCLLGLSYSLLACALWPMVAFVVPEHQLGTAYGFMQSIQNLGLAVISIIAGMILDTRGYLFLEVFFIACVSLSLLSVVLLYMVNHAQGGNLNYSAKKREEMKLSHEE", "length": 468 }, "evidence": [ { "id": "F1P182", "url": "https://omabrowser.org/oma/group/F1P182/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q9DC37-1", "protein_name": "Lysosomal dipeptide transporter MFSD1", "gene_name": "Mfsd1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEDEDGEDRALLGGRREADSAVHGAPRALSALCDPSRLAHRLVVLSLMCFLGFGSYFCYDNPAALQTQVKRDMQVNTTKFMLLYAWYSWPNVVLCFLGGFLIDRIFGIRWGTVIFSCFVCIGQVIFALGGIFNAFWLMELGRFVFGIGGESLAVAQNTYAVSWFKGKELNLVFGLQLSMARIGSTVNMNLMGWLYGKIEALLGSAGHMTLGVTLMIGCITCIFSLICALALAYLDRRAEKILHKEQGKTGEVIKLRDIKDFSLPLILVFVICVCYYVAVFPFIGLGKVFFMEKFRFSSQSASAINSIVYIISAPMSPLFGLLVDKTGKNIIWVLYAVAATLVSHMMLAFTFWNPWIAMCLLGFSYSLLACALWPMVAFIVPEHQLGTAYGFMQSIQNLGLAVIAILAGMILDSKGYLLLEVFFIACVSLSLLAVVCLYLVNRAQGGNLNYSAKQRERMKLSHPE", "length": 464 }, "evidence": [ { "id": "F1P182", "url": "https://omabrowser.org/oma/group/F1P182/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9H3U5-1", "protein_name": "Lysosomal dipeptide transporter MFSD1", "gene_name": "MFSD1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEEEDEEARALLAGGPDEADRGAPAAPGALPALCDPSRLAHRLLVLLLMCFLGFGSYFCYDNPAALQTQVKRDMQVNTTKFMLLYAWYSWPNVVLCFFGGFLIDRVFGIRWGTIIFSCFVCIGQVVFALGGIFNAFWLMEFGRFVFGIGGESLAVAQNTYAVSWFKGKELNLVFGLQLSMARIGSTVNMNLMGWLYSKIEALLGSAGHTTLGITLMIGGITCILSLICALALAYLDQRAERILHKEQGKTGEVIKLTDVKDFSLPLWLIFIICVCYYVAVFPFIGLGKVFFTEKFGFSSQAASAINSVVYVISAPMSPVFGLLVDKTGKNIIWVLCAVAATLVSHMMLAFTMWNPWIAMCLLGLSYSLLACALWPMVAFVVPEHQLGTAYGFMQSIQNLGLAIISIIAGMILDSRGYLFLEVFFIACVSLSLLSVVLLYLVNRAQGGNLNYSARQREEIKFSHTE", "length": 465 }, "evidence": [ { "id": "F1P182", "url": "https://omabrowser.org/oma/group/F1P182/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VS47-1", "protein_name": "Lysosomal dipeptide transporter MFSD1", "gene_name": "mrva", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MAREDEERIVDNEEVSRPTEEDQVVSRAGRRDNELSLPSGGCCMPSSTSHRFMALVFMCLLGFGSYFCYDAPGALQNYFKKDLNLTSAQFTLIYSIYSWPNVVLCFVGGFLIDRLFGIRLGTIIYMMILLVGQLIFACGGILDAFWMMILGRFIFGIGAESLAVAQNSYAVLWFKGKELNMVFGLQLSVARFGSTVNFWVMQPIYEYVSNFYKGHTALGVVLLLATLTCVMSMTCALILGWMDKRAERILQRNNNPAGQIPKLTDVFSFKPPFWMVSIICVAYYVAIFPFIALGQNFFVDRFGLSPAEANTVDSLVYLIAAVSSPVFGFIIDKLGRNVTWVFTATLTTIGAHALLTFTQLTPYVGMIIMGLSYSMLAASLWPLVALIIPEYQLGTAYGFCQSIQNLGLAVITIVAGIIVDHSGGEHMWLQLFFMGWLTIALISTGVIWAYNNKNRGNLNMTPQQRAQFVSAENYQNFE", "length": 478 }, "evidence": [ { "id": "F1P182", "url": "https://omabrowser.org/oma/group/F1P182/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "transmembrane transporter activity", "id": "GO:0022857", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022857", "evidence": [ { "database": "UniProtKB", "id": "F1P182", "url": "https://www.uniprot.org/uniprotkb/F1P182" } ], "pmid": "" }, { "name": "protein homodimerization activity", "id": "GO:0042803", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042803", "evidence": [ { "database": "UniProtKB", "id": "F1P182", "url": "https://www.uniprot.org/uniprotkb/F1P182" } ], "pmid": "" }, { "name": "dipeptide uniporter activity", "id": "GO:0160178", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160178", "evidence": [ { "database": "UniProtKB", "id": "F1P182", "url": "https://www.uniprot.org/uniprotkb/F1P182" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "lysosomal membrane", "id": "GO:0005765", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005765", "evidence": [ { "database": "UniProtKB", "id": "F1P182", "url": "https://www.uniprot.org/uniprotkb/F1P182" } ], "pmid": "" }, { "name": "lysosome", "id": "GO:0005764", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005764", "evidence": [ { "database": "UniProtKB", "id": "F1P182", "url": "https://www.uniprot.org/uniprotkb/F1P182" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "protein stabilization", "id": "GO:0050821", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050821", "evidence": [ { "database": "UniProtKB", "id": "F1P182", "url": "https://www.uniprot.org/uniprotkb/F1P182" } ], "pmid": "" }, { "name": "protein localization to lysosome", "id": "GO:0061462", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061462", "evidence": [ { "database": "UniProtKB", "id": "F1P182", "url": "https://www.uniprot.org/uniprotkb/F1P182" } ], "pmid": "" }, { "name": "dipeptide transmembrane transport from lysosomal lumen to cytosol", "id": "GO:0141204", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0141204", "evidence": [ { "database": "UniProtKB", "id": "F1P182", "url": "https://www.uniprot.org/uniprotkb/F1P182" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 256, "end_pos": 258, "annotation": "n_glycosylation_sequon" }, { "start_pos": 445, "end_pos": 447, "annotation": "n_glycosylation_sequon" }, { "start_pos": 503, "end_pos": 505, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "79367", "name": "", "equation": "L-alpha-aminoacyl-L-arginine(out) = L-alpha-aminoacyl-L-arginine(in)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "79367", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/79367" } ] }, { "id": "79371", "name": "", "equation": "L-arginyl-L-alpha-amino acid(out) = L-arginyl-L-alpha-amino acid(in)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "79371", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/79371" } ] }, { "id": "79375", "name": "", "equation": "L-alpha-aminoacyl-L-histidine(out) = L-alpha-aminoacyl-L-histidine(in)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "79375", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/79375" } ] }, { "id": "79379", "name": "", "equation": "L-histidyl-L-alpha-amino acid(out) = L-histidyl-L-alpha-amino acid(in)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "79379", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/79379" } ] }, { "id": "79383", "name": "", "equation": "L-alpha-aminoacyl-L-lysine(out) = L-alpha-aminoacyl-L-lysine(in)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "79383", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/79383" } ] }, { "id": "79387", "name": "", "equation": "L-lysyl-L-alpha-amino acid(out) = L-lysyl-L-alpha-amino acid(in)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "79387", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/79387" } ] }, { "id": "79391", "name": "", "equation": "L-arginyl-glycine(out) = L-arginyl-glycine(in)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "79391", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/79391" } ] }, { "id": "79395", "name": "", "equation": "L-histidyl-glycine(out) = L-histidyl-glycine(in)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "79395", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/79395" } ] }, { "id": "79399", "name": "", "equation": "L-lysyl-L-alanine(out) = L-lysyl-L-alanine(in)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "79399", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/79399" } ] }, { "id": "79403", "name": "", "equation": "L-lysyl-L-lysine(out) = L-lysyl-L-lysine(in)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "79403", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/79403" } ] }, { "id": "79407", "name": "", "equation": "L-lysyl-glycine(out) = L-lysyl-glycine(in)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "79407", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/79407" } ] }, { "id": "79411", "name": "", "equation": "L-aspartyl-L-lysine(out) = L-aspartyl-L-lysine(in)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "79411", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/79411" } ] }, { "id": "79415", "name": "", "equation": "L-alanyl-L-lysine(out) = L-alanyl-L-lysine(in)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "79415", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/79415" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1P182-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 518, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1P182-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1P182" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1P182", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P182" }, { "id": "PS50850", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50850" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Major facilitator superfamily (MFS) profile", "eco_id": "ECO_0000259", "start_pos": 37, "end_pos": 441, "start_aa": "Arg", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 256, "end_pos": 258 }, { "start_pos": 445, "end_pos": 447 }, { "start_pos": 503, "end_pos": 505 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1NHS7-1", "uniprot_ac": "F1NHS7", "uniprot_id": "F1NHS7_CHICK", "mass": { "chemical_mass": 18615.0, "monoisotopic_mass": 18615.0 }, "refseq": { "ac": "NP_001006261", "name": "AP-1 complex subunit sigma-2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006261" }, "gene_names": [ { "name": "AP1S2", "type": "recommended", "evidence": [ { "id": "F1NHS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NHS7" } ] }, { "name": "AP1S2", "type": "synonym", "evidence": [ { "id": "NP_001006261", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006261" } ] } ], "protein_names": [ { "name": "AP complex subunit sigma", "type": "recommended", "evidence": [ { "id": "F1NHS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NHS7/entry#names_and_taxonomy" } ] }, { "name": "AP-1 complex subunit sigma-2", "type": "synonym", "evidence": [ { "id": "NP_001006261", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006261" } ] }, { "name": "adaptor related protein complex 1 subunit sigma 2", "type": "synonym", "evidence": [ { "id": "NP_001006261", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006261" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ720066.1, SRR13267654.184764.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000022.1. On Sep 23, 2021 this sequence version replaced NP_001006261.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001006261", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006261" } ] }, { "annotation": "Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules.", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PB56", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PB56#function" }, { "database": "UniProtKB", "id": "ARBA00059060", "url": "https://www.uniprot.org/uniprotkb/ARBA00059060#function" }, { "database": "UniProtKB", "id": "A0A8V0X5U8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X5U8#function" }, { "database": "UniProtKB", "id": "A0A8V0XBT5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XBT5#function" }, { "database": "UniProtKB", "id": "A0A8V0XBU1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XBU1#function" }, { "database": "UniProtKB", "id": "F1NHS7", "url": "https://www.uniprot.org/uniprotkb/F1NHS7#function" }, { "database": "UniProtKB", "id": "A0A8V0XBM2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XBM2#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NHS7", "url": "https://www.uniprot.org/uniprotkb/F1NHS7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "AP1S2", "url": "https://www.uniprot.org/uniprotkb/F1NHS7", "locus": { "chromosome": "1", "start_pos": 121984435, "end_pos": 121950307, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010001510", "url": "https://www.ensembl.org/id/ENSGALG00010001510" } ] } } ], "crossref": [ { "id": "F1NHS7", "url": "https://alphafold.ebi.ac.uk/entry/F1NHS7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000016551", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000016551", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd14831", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14831", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "418621", "url": "https://www.ncbi.nlm.nih.gov/gene/418621", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000804", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000804", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011012", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011012", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016635", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016635", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR022775", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022775", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044733", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044733", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:418621", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418621", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "KAYHILD", "url": "https://omabrowser.org/oma/group/KAYHILD/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PB56", "url": "https://www.orthodb.org/?gene=A0A1D5PB56", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0X5U8", "url": "https://www.orthodb.org/?gene=A0A8V0X5U8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XBM2", "url": "https://www.orthodb.org/?gene=A0A8V0XBM2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XBT5", "url": "https://www.orthodb.org/?gene=A0A8V0XBT5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XBU1", "url": "https://www.orthodb.org/?gene=A0A8V0XBU1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NHS7", "url": "https://www.orthodb.org/?gene=F1NHS7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11753", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11753", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01217", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01217", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-432720", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-432720", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-432722", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-432722", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001006261", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006261", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5PB56", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PB56", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PB56-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PB56-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0X5U8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X5U8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0X5U8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X5U8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XBM2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XBM2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XBM2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XBM2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XBT5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XBT5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XBT5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XBT5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XBU1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XBU1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XBU1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XBU1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NHS7", "url": "https://www.uniprot.org/uniprotkb/F1NHS7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NHS7-1", "url": "https://www.uniprot.org/uniprotkb/F1NHS7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQFMLLFSRQGKLRLQKWYVPLSDKEKKKITRELVQTVLARKPKMCSFLEWRDLKIVYKRYASLYFCCAIEDQDNELITLEIIHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFLLGGEVQETSKKNVLKAIEQADLLQEEAETPRSVLEEIGLT", "length": 157, "header": "tr|F1NHS7-1|F1NHS7_CHICK Isoform 1 of AP complex subunit sigma OS=Gallus gallus OX=9031 GN=AP1S2 PE=1 SV=2 CANONICAL=F1NHS7-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PB56-1", "url": "https://www.uniprot.org/uniprotkb/F1NHS7/entry#A0A1D5PB56-1", "sequence": { "sequence": "MQFMLLFSRQGKLRLQKWYVPLSDKEKKKITRELVQTVLARKPKMCSFLEWRDLKIVYKRYASLYFCCAIEDQDNELITLEIIHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFLLGGEVQETSKKNVLKAIEQADLLQESQNEDWGGLSEDIL", "length": 156, "header": "tr|A0A1D5PB56-1|A0A1D5PB56_CHICK Computationally mapped isoform of AP complex subunit sigma OS=Gallus gallus OX=9031 GN=AP1S2 PE=3 SV=1 CANONICAL=F1NHS7-1" }, "locus": { "chromosome": "1", "start_pos": 121970871, "end_pos": 121951619, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010003496.1", "url": "https://www.ensembl.org/id/ENSGALT00010003496.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010001938.1", "url": "https://www.ensembl.org/id/ENSGALP00010001938.1" } ] } }, { "isoform_ac": "A0A8V0X5U8-1", "url": "https://www.uniprot.org/uniprotkb/F1NHS7/entry#A0A8V0X5U8-1", "sequence": { "sequence": "MQFMLLFSRQGKLRLQKWYVPLSDKEKKKITRELVQTVLARKPKMCSFLEWRDLKIVYKRYASLYFCCAIEDQDNELITLEIIHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFLLGGEVQETSKKNVLKAIEQADLLQESQNEDWGATS", "length": 152, "header": "tr|A0A8V0X5U8-1|F1NHS7_CHICK Computationally mapped isoform of AP complex subunit sigma OS=Gallus gallus OX=9031 GN=AP1S2 PE=1 SV=1 CANONICAL=F1NHS7-1" }, "locus": { "chromosome": "1", "start_pos": 121978680, "end_pos": 121951619, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010003492.1", "url": "https://www.ensembl.org/id/ENSGALT00010003492.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010001934.1", "url": "https://www.ensembl.org/id/ENSGALP00010001934.1" } ] } }, { "isoform_ac": "A0A8V0XBM2-1", "url": "https://www.uniprot.org/uniprotkb/F1NHS7/entry#A0A8V0XBM2-1", "sequence": { "sequence": "MQFMLLFSRQGKLRLQKWYVPLSDKEKKKITRELVQTVLARKPKMCSFLEWRDLKIVYKRYASLYFCCAIEDQDNELITLEIIHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFLLGGEVQETSKKNVLKAIEQADLLQESQMSSSKSGIEYPSSCRTRAALKVIPPTLLHWAMMSEADGDMAIEVEPSHQYSITFYCRITDGNRRAV", "length": 210, "header": "tr|A0A8V0XBM2-1|A0A8V0XBM2_CHICK Computationally mapped isoform of AP-1 complex subunit sigma-2 OS=Gallus gallus OX=9031 GN=AP1S2 PE=3 SV=1 CANONICAL=F1NHS7-1" }, "locus": { "chromosome": "1", "start_pos": 121968262, "end_pos": 121951619, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010003491.1", "url": "https://www.ensembl.org/id/ENSGALT00010003491.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010001933.1", "url": "https://www.ensembl.org/id/ENSGALP00010001933.1" } ] } }, { "isoform_ac": "A0A8V0XBT5-1", "url": "https://www.uniprot.org/uniprotkb/F1NHS7/entry#A0A8V0XBT5-1", "sequence": { "sequence": "MQFMLLFSRQGKLRLQKWYVPLSDKEKKKITRELVQTVLARKPKMCSFLEWRDLKIVYKRYASLYFCCAIEDQDNELITLEIIHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFLLGGEVQETSKKNVLKAIEQADLLQEDAKEAETPRSVLEEIGLT", "length": 160, "header": "tr|A0A8V0XBT5-1|F1NHS7_CHICK Computationally mapped isoform of AP complex subunit sigma OS=Gallus gallus OX=9031 GN=AP1S2 PE=1 SV=1 CANONICAL=F1NHS7-1" }, "locus": { "chromosome": "1", "start_pos": 121982372, "end_pos": 121951619, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010003494.1", "url": "https://www.ensembl.org/id/ENSGALT00010003494.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010001936.1", "url": "https://www.ensembl.org/id/ENSGALP00010001936.1" } ] } }, { "isoform_ac": "A0A8V0XBU1-1", "url": "https://www.uniprot.org/uniprotkb/F1NHS7/entry#A0A8V0XBU1-1", "sequence": { "sequence": "MLLFSRQGKLRLQKWYVPLSDKEKKKITRELVQTVLARKPKMCSFLEWRDLKIVYKRYASLYFCCAIEDQDNELITLEIIHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFLLGGEVQETSKKNVLKAIEQADLLQESQNEDWGGLSEDIL", "length": 153, "header": "tr|A0A8V0XBU1-1|F1NHS7_CHICK Computationally mapped isoform of AP complex subunit sigma OS=Gallus gallus OX=9031 GN=AP1S2 PE=1 SV=1 CANONICAL=F1NHS7-1" }, "locus": { "chromosome": "1", "start_pos": 121970871, "end_pos": 121951628, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010003499.1", "url": "https://www.ensembl.org/id/ENSGALT00010003499.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010001941.1", "url": "https://www.ensembl.org/id/ENSGALP00010001941.1" } ] } }, { "isoform_ac": "F1NHS7-1", "url": "https://www.uniprot.org/uniprotkb/F1NHS7/entry#F1NHS7-1", "sequence": { "sequence": "MQFMLLFSRQGKLRLQKWYVPLSDKEKKKITRELVQTVLARKPKMCSFLEWRDLKIVYKRYASLYFCCAIEDQDNELITLEIIHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFLLGGEVQETSKKNVLKAIEQADLLQEEAETPRSVLEEIGLT", "length": 157, "header": "tr|F1NHS7-1|F1NHS7_CHICK Isoform 1 of AP complex subunit sigma OS=Gallus gallus OX=9031 GN=AP1S2 PE=1 SV=2 CANONICAL=F1NHS7-1" }, "locus": { "chromosome": "1", "start_pos": 121982372, "end_pos": 121951619, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010003498.1", "url": "https://www.ensembl.org/id/ENSGALT00010003498.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010001940.1", "url": "https://www.ensembl.org/id/ENSGALP00010001940.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:418621", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418621", "resource": "KEGG Pathway" }, { "id": "R-GGA-432720", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-432720", "resource": "Reactome", "description": "Lysosome Vesicle Biogenesis" }, { "id": "R-GGA-432722", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-432722", "resource": "Reactome", "description": "Golgi Associated Vesicle Biogenesis" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I5ZVG9-1", "protein_name": "AP complex subunit sigma", "gene_name": "Ap1s2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQFMLLFSRQGKLRLQKWYVPLSDKEKKKITRELVQTVLARKPKMCSFLEWRDLKIVYKRYASLYFCCAIEDQDNELITLEIIHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFLLGGEVQETSKKNVLKAIEQADLLQEDAKEAETPRSVLEEIGLT", "length": 160 }, "evidence": [ { "id": "F1NHS7", "url": "https://omabrowser.org/oma/group/F1NHS7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A9J7K0Y8-1", "protein_name": "AP complex subunit sigma", "gene_name": "Ap1s2", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MQFMLLFSRQGKLRLQKWYVPLSDKEKKKITRELVQTVLARKPKMCSFLEWRDLKIVYKRYASLYFCCAIEDQDNELITLEIIHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFLLGGEVQETSKKNVLKAIEQADLLQEKKQTMYHSKSFIGYKRAY", "length": 160 }, "evidence": [ { "id": "F1NHS7", "url": "https://omabrowser.org/oma/group/F1NHS7/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "B0G185-1", "protein_name": "AP-1 complex subunit sigma-2", "gene_name": "ap1s2", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MTFHFLLLLSRQGKTRLTKWYSPFTNKEKSRFTREIGNMVLNRPPKLCNFLEWKEYKIIFKRYASLYFVVCCDREDNELIVLEIIHHFVEILDRYFGNVCELDLIFNFHKAYYILDELIMAGELQETSKKTVLRLISQQDTLLEGGPGEHKVDL", "length": 154 }, "evidence": [ { "id": "F1NHS7", "url": "https://omabrowser.org/oma/group/F1NHS7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "O23685-1", "protein_name": "AP-1 complex subunit sigma-2", "gene_name": "AAP19-2", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MIHFVLLVSRQGKVRLTKWYSPYAQKERSKVIRELSGVILNRGPKLCNFVEWRGYKVVYKRYASLYFCMCIDQEDNELEVLEIIHHYVEILDRYFGSVCELDLIFNFHKAYYILDELLIAGELQESSKKTVARIISAQDQLVEVAKEEASSISNIIAQATNR", "length": 162 }, "evidence": [ { "id": "F1NHS7", "url": "https://omabrowser.org/oma/group/F1NHS7/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "P35181-1", "protein_name": "AP-1 complex subunit sigma-1", "gene_name": "APS1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MTQLKYLLLVSRQGKIRLKKWYTAMSAGEKAKIVKDLTPTILARKPKMCNIIEYNDHKVVYKRYASLYFIVGMTPDVDNELLTLEIIHRFVETMDTYFGNVCELDIIFNFSKVYDILNEMIMCDGSIAESSRKEVLHHVTVMDTMESNDNLERVLS", "length": 156 }, "evidence": [ { "id": "F1NHS7", "url": "https://omabrowser.org/oma/group/F1NHS7/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P56377-1", "protein_name": "AP-1 complex subunit sigma-2", "gene_name": "AP1S2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MQFMLLFSRQGKLRLQKWYVPLSDKEKKKITRELVQTVLARKPKMCSFLEWRDLKIVYKRYASLYFCCAIEDQDNELITLEIIHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFLLGGEVQETSKKNVLKAIEQADLLQEEAETPRSVLEEIGLT", "length": 157 }, "evidence": [ { "id": "F1NHS7", "url": "https://omabrowser.org/oma/group/F1NHS7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9DB50-1", "protein_name": "AP-1 complex subunit sigma-2", "gene_name": "Ap1s2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MQFMLLFSRQGKLRLQKWYVPLSDKEKKKITRELVQTVLARKPKMCSFLEWRDLKIVYKRYASLYFCCAIEDQDNELITLEIIHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFLLGGEVQETSKKNVLKAIEQADLLQEDAKEAETPRSVLEEIGLT", "length": 160 }, "evidence": [ { "id": "F1NHS7", "url": "https://omabrowser.org/oma/group/F1NHS7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "clathrin-coated pit", "id": "GO:0005905", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005905", "evidence": [ { "database": "UniProtKB", "id": "F1NHS7", "url": "https://www.uniprot.org/uniprotkb/F1NHS7" } ], "pmid": "" }, { "name": "AP-1 adaptor complex", "id": "GO:0030121", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030121", "evidence": [ { "database": "UniProtKB", "id": "F1NHS7", "url": "https://www.uniprot.org/uniprotkb/F1NHS7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "intracellular protein transport", "id": "GO:0006886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006886", "evidence": [ { "database": "UniProtKB", "id": "F1NHS7", "url": "https://www.uniprot.org/uniprotkb/F1NHS7" } ], "pmid": "" }, { "name": "vesicle-mediated transport", "id": "GO:0016192", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016192", "evidence": [ { "database": "UniProtKB", "id": "F1NHS7", "url": "https://www.uniprot.org/uniprotkb/F1NHS7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "clathrin adaptor activity", "id": "GO:0035615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035615", "evidence": [ { "database": "UniProtKB", "id": "F1NHS7", "url": "https://www.uniprot.org/uniprotkb/F1NHS7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1NHS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NHS7" }, { "id": "PF01217", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01217" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "AP complex mu/sigma subunit", "eco_id": "ECO_0000259", "start_pos": 1, "end_pos": 140, "start_aa": "Met", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": 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"F1P0Z3_CHICK", "mass": { "chemical_mass": 62001.0, "monoisotopic_mass": 62001.0 }, "refseq": { "ac": "XP_015150351", "name": "putative phospholipase B-like 2 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015150351" }, "gene_names": [ { "name": "PLBD2", "type": "recommended", "evidence": [ { "id": "F1P0Z3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P0Z3" } ] }, { "name": "PLBD2", "type": "synonym", "evidence": [ { "id": "XP_015150351", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015150351" } ] } ], "protein_names": [ { "name": "Phospholipase B-like", "type": "recommended", "evidence": [ { "id": "F1P0Z3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P0Z3/entry#names_and_taxonomy" } ] }, { "name": "3.1.1.-", "type": "synonym", "evidence": [ { "id": "F1P0Z3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P0Z3/entry#names_and_taxonomy" } ] }, { "name": "putative phospholipase B-like 2 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015150351", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015150351" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052546.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015150351", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015150351" } ] }, { "annotation": "Putative phospholipase.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0X7D0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X7D0#function" }, { "database": "UniProtKB", "id": "RU364138", "url": "https://www.uniprot.org/uniprotkb/RU364138#function" }, { "database": "UniProtKB", "id": "F1P0Z3", "url": "https://www.uniprot.org/uniprotkb/F1P0Z3#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1P0Z3", "url": "https://www.uniprot.org/uniprotkb/F1P0Z3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PLBD2", "url": "https://www.uniprot.org/uniprotkb/F1P0Z3", "locus": { "chromosome": "15", "start_pos": 12586528, "end_pos": 12589699, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010000449", "url": "https://www.ensembl.org/id/ENSGALG00010000449" } ] } } ], "crossref": [ { "id": "F1P0Z3", "url": "https://alphafold.ebi.ac.uk/entry/F1P0Z3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000008319", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000008319", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "417031", "url": "https://www.ncbi.nlm.nih.gov/gene/417031", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR007000", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007000", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:417031", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417031", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YQEGYWA", "url": "https://omabrowser.org/oma/group/YQEGYWA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0X7D0", "url": "https://www.orthodb.org/?gene=A0A8V0X7D0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1P0Z3", "url": "https://www.orthodb.org/?gene=F1P0Z3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12370", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12370", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12370:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12370:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04916", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04916", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015150351", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015150351", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0X7D0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X7D0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0X7D0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X7D0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1P0Z3", "url": "https://www.uniprot.org/uniprotkb/F1P0Z3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1P0Z3-1", "url": "https://www.uniprot.org/uniprotkb/F1P0Z3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAALRALLAAAAVAAWVLGVASGPTPPPRSASVLLEPGSGRLRVLPGRQPAAVAWAELTDHIQAVGWAFLEVSANASFNDSLQAYAAGLAEAAVTEQLIYMHWMNTAVGYCGPFRYETQYCRRLRGYLEANLAWMEEQMASGRDRAYWHQVRLALLQLQGLEDSYRGRVALPAGRISLSPFGFLLLQLGGDLEDLEAAFNRSAPRRLLGSGSCSALLKLLPGRRDLLVAHDTWAPYQSMLRVIKKYTLPFRTEPGSTARVPGSIQVFSSYPGTIFSGDDFYILSSGLVALETTIGNSDEARWRYLRPQGSVLEWLRNIVANRLARSGAEWASIFQRFNSGTYNNQWMLVDYKAFSPGQAAPQQGLLTVLEQIPGLVMVADKTELLYKQGYWASYNVPYFEEIFNASGNLELVQKYGDWFTYDKNPRAQIFRRNETQVHDVDSMVRLMRSNNYLQDPLSQCQGCNPPHNAENAISARSDLNPANGTYPFAALRQRCHGGTDTKVTSFGMARTFGLVAASGPTWDDVPPFRWSTSPCSHLLRMGHPDLWRFPPVKVRWD", "length": 557, "header": "tr|F1P0Z3-1|F1P0Z3_CHICK Isoform 1 of Phospholipase B-like OS=Gallus gallus OX=9031 GN=PLBD2 PE=1 SV=3 CANONICAL=F1P0Z3-1" }, "isoforms": [ { "isoform_ac": "A0A8V0X7D0-1", "url": "https://www.uniprot.org/uniprotkb/F1P0Z3/entry#A0A8V0X7D0-1", "sequence": { "sequence": "MAALRALLAAAAVAAWVLGVASGPTPPPRSASVLLEPGSGRLRVLPGRQPAAVAWAELTDHIQAVGWAFLEVSANASFNDSLQAYAAGLAEAAVTEQLIYMHWMNTAVGYCGPFRYETQYCRRLRGYLEANLAWMEEQMASGRDRAYWHQVRLALLQLQGLEDSYRGRVALPAGRISLSPFGFLLLQLGGDLEDLEAAFNRSAPRRLLGSGSCSALLKLLPGRRDLLVAHDTWAPYQSMLRVIKKYTLPFRTEPGSTARVPGSIQVFSSYPGTIFSGDDFYILSSGLVALETTIGNSDEARWRYLRPQGSVLEWLRNIVANRLARSGAEWASIFQRFNSGTYNNQWMLVDYKAFSPGQAAPQQGLLTVLEQIPYFEEIFNASGNLELVQKYGDWFTYDKNPRAQIFRRNETQVHDVDSMVRLMRSNNYLQDPLSQCQGCNPPHNAENAISARSDLNPANGTYPFAALRQRCHGGTDTKVTSFGMARTFGLVAASGPTWDDVPPFRWSTSPCSHLLRMGHPDLWRFPPVKVRWD", "length": 533, "header": "tr|A0A8V0X7D0-1|F1P0Z3_CHICK Computationally mapped isoform of Phospholipase B-like OS=Gallus gallus OX=9031 GN=PLBD2 PE=1 SV=1 CANONICAL=F1P0Z3-1" }, "locus": { "chromosome": "15", "start_pos": 12589672, "end_pos": 12586892, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010000937.1", "url": "https://www.ensembl.org/id/ENSGALT00010000937.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010000498.1", "url": "https://www.ensembl.org/id/ENSGALP00010000498.1" } ] } }, { "isoform_ac": "F1P0Z3-1", "url": "https://www.uniprot.org/uniprotkb/F1P0Z3/entry#F1P0Z3-1", "sequence": { "sequence": "MAALRALLAAAAVAAWVLGVASGPTPPPRSASVLLEPGSGRLRVLPGRQPAAVAWAELTDHIQAVGWAFLEVSANASFNDSLQAYAAGLAEAAVTEQLIYMHWMNTAVGYCGPFRYETQYCRRLRGYLEANLAWMEEQMASGRDRAYWHQVRLALLQLQGLEDSYRGRVALPAGRISLSPFGFLLLQLGGDLEDLEAAFNRSAPRRLLGSGSCSALLKLLPGRRDLLVAHDTWAPYQSMLRVIKKYTLPFRTEPGSTARVPGSIQVFSSYPGTIFSGDDFYILSSGLVALETTIGNSDEARWRYLRPQGSVLEWLRNIVANRLARSGAEWASIFQRFNSGTYNNQWMLVDYKAFSPGQAAPQQGLLTVLEQIPGLVMVADKTELLYKQGYWASYNVPYFEEIFNASGNLELVQKYGDWFTYDKNPRAQIFRRNETQVHDVDSMVRLMRSNNYLQDPLSQCQGCNPPHNAENAISARSDLNPANGTYPFAALRQRCHGGTDTKVTSFGMARTFGLVAASGPTWDDVPPFRWSTSPCSHLLRMGHPDLWRFPPVKVRWD", "length": 557, "header": "tr|F1P0Z3-1|F1P0Z3_CHICK Isoform 1 of Phospholipase B-like OS=Gallus gallus OX=9031 GN=PLBD2 PE=1 SV=3 CANONICAL=F1P0Z3-1" }, "locus": { "chromosome": "15", "start_pos": 12589672, "end_pos": 12586892, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010000936.1", "url": "https://www.ensembl.org/id/ENSGALT00010000936.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010000497.1", "url": "https://www.ensembl.org/id/ENSGALP00010000497.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 25, "start_aa": "Thr", "end_pos": 25, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr25", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 521, "start_aa": "Thr", "end_pos": 521, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr521", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:417031", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417031", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "F1MIH9-1", "protein_name": "Phospholipase B domain containing 2", "gene_name": "PLBD2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MVAPMYGSPGGRLARAVTRALALALVLALLVGLFLSGLTGAIPTPRGQRGRGMPVPPASRCRSLLLDPETGQLRLVDGRHPDAVAWANLTNAIRETGWAFLELHTNGRFNDSLQAYAAGVVEAAVSEELIYMYWMNTVVNYCGPFEYEVGYCERLKNFLEANLEWMQKEMELNNGSAYWHQVRLTLLQLKGLEDSYEGSVAFPTGKFTVKPLGFLLLQISGDLEDLEVALNKTKTNHAMGSGSCSALIKLLPGQRDLLVAHNTWHSYQYMLRIMKKYWFQFREGPQAESTRAPGNKVIFSSYPGTIFSCDDFYILGSGLVTLETTIGNKNPALWKYVQPTGCVLEWMRNVVANRLALDGDSWADIFKRFNSGTYNNQWMIVDYKAFVPGGPSPGRRVLTVLEQIPGMVVVADRTSELYQKTYWASYNIPSFESVFNASGLPALVARYGPWFSYDGSPRAQIFRRNHSLVHDLDSMMRLMRYNDFLHDPLSLCKACTPKPNGENAISARSDLNPANGSYPFQALHQRSHGGIDVKVTSTALAKALRLLAVSGPTWDQLPPFQWSTSPFSGMLHMGQPDLWKFSPIEVSWD", "length": 589 }, "evidence": [ { "id": "F1P0Z3", "url": "https://omabrowser.org/oma/group/F1P0Z3/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "G3I6T1-1", "protein_name": "Phospholipase B-like 2", "gene_name": "Plbd2", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAAPMDRSPGGRAVRALRLALALASLTEVLLNCPAGALPTQGPGRRRQNLDPPVSRVRSVLLDAASGQLRLVDGIHPYAVAWANLTNAIRETGWAYLDLGTNGSYNDSLQAYAAGVVEASVSEELIYMHWMNTMVNYCGPFEYEVGYCEKLKSFLEINLEWMQREMELSQDSPYWHQVRLTLLQLKGLEDSYEGRLTFPTGRFTIKPLGFLLLQIAGDLEDLEQALNKTSTKLSLGSGSCSAIIKLLPGARDLLVAHNTWNSYQNMLRIIKKYQLQFRQGPQEAYPLIAGNNLVFSSYPGTIFSGDDFYILGSGLVTLETTIGNKNPALWKYVQPQGCVLEWIRNIVANRLALDGATWADIFKQFNSGTYNNQWMIVDYKAFIPNGPSPGSRVLTILEQIPGMVVVADKTEDLYKTTYWASYNIPFFEIVFNASGLQDLVAQYGDWFSYTKNPRAQIFQRDQSLVEDMNSMVRLIRYNNFLHDPLSLCEACIPKPNAENAISARSDLNPANGSYPFQALYQRPHGGIDVKVTSFSLAKRMSMLAASGPTWDQLPPFQWSLSPFRSMLHMGQPDLWTFSPISVPWD", "length": 585 }, "evidence": [ { "id": "F1P0Z3", "url": "https://omabrowser.org/oma/group/F1P0Z3/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q3TCN2-1", "protein_name": "Putative phospholipase B-like 2", "gene_name": "Plbd2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAPVDGSSGGWAARALRRALALTSLTTLALLASLTGLLLSGPAGALPTLGPGWQRQNPDPPVSRTRSLLLDAASGQLRLEDGFHPDAVAWANLTNAIRETGWAYLDLSTNGRYNDSLQAYAAGVVEASVSEELIYMHWMNTVVNYCGPFEYEVGYCEKLKNFLEANLEWMQREMELNPDSPYWHQVRLTLLQLKGLEDSYEGRLTFPTGRFTIKPLGFLLLQISGDLEDLEPALNKTNTKPSLGSGSCSALIKLLPGGHDLLVAHNTWNSYQNMLRIIKKYRLQFREGPQEEYPLVAGNNLVFSSYPGTIFSGDDFYILGSGLVTLETTIGNKNPALWKYVQPQGCVLEWIRNVVANRLALDGATWADVFKRFNSGTYNNQWMIVDYKAFLPNGPSPGSRVLTILEQIPGMVVVADKTAELYKTTYWASYNIPYFETVFNASGLQALVAQYGDWFSYTKNPRAKIFQRDQSLVEDMDAMVRLMRYNDFLHDPLSLCEACNPKPNAENAISARSDLNPANGSYPFQALHQRAHGGIDVKVTSFTLAKYMSMLAASGPTWDQCPPFQWSKSPFHSMLHMGQPDLWMFSPIRVPWD", "length": 594 }, "evidence": [ { "id": "F1P0Z3", "url": "https://omabrowser.org/oma/group/F1P0Z3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q4QQW8-1", "protein_name": "Putative aminopeptidase PLBD2", "gene_name": "Plbd2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAAPMDRTHGGRAARALRRALALASLAGLLLSGLAGALPTLGPGWRRQNPEPPASRTRSLLLDAASGQLRLEYGFHPDAVAWANLTNAIRETGWAYLDLGTNGSYNDSLQAYAAGVVEASVSEELIYMHWMNTVVNYCGPFEYEVGYCEKLKSFLEANLEWMQREMELSPDSPYWHQVRLTLLQLKGLEDSYEGRLTFPTGRFNIKPLGFLLLQISGDLEDLEPALNKTNTKPSVGSGSCSALIKLLPGSHDLLVAHNTWNSYQNMLRIIKKYRLQFREGPQEEYPLIAGNNLIFSSYPGTIFSGDDFYILGSGLVTLETTIGNKNPALWKYVQPQGCVLEWIRNIVANRLALDGATWADVFRRFNSGTYNNQWMIVDYKAFIPNGPSPGSRVLTILEQIPGMVVVADKTAELYKTTYWASYNIPYFESVFNASGLQALVAQYGDWFSYTRNPRAKIFQRDQSLVEDVDTMVRLMRYNDFLHDPLSLCEACSPKPNAENAISARSDLNPANGSYPFQALRQRAHGGIDVKVTSVALAKYMSMLAASGPTWDQLPPFQWSKSPFHNMLHMGQPDLWMFSPVKVPWD", "length": 585 }, "evidence": [ { "id": "F1P0Z3", "url": "https://omabrowser.org/oma/group/F1P0Z3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q55BJ6-1", "protein_name": "Phospholipase B-like protein B", "gene_name": "plbB", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNKLKSNFILNIVILFTILIFNINFINCENQKQQQHQQQQQQQQQQSSSTTTTLPIYSIKFSSETGFTIYSGNDSTSIAQSGFSNEMMTMGWAYLTITTNSQFEDSLQAEAAGYIEGYLTFEMIWQCWYNILVNEYQNQTIPNQVLNWANENIAYMKQQVATNENDPYWINIGLVLTQLSGMVDGYNAANQDPSRQLSFLDFILINMDADLGDISSTFNQSTSFSEISNFKKSMDHIKKTDHCSGLIKLTDDLTELYSAHTSWSSYINMLRIFKSYNFKFSSITNIKSKLTLFSGYPATIASLDDFYLLDTKLVVLETTNGLNNNDLYYLIKPESVLTWMRVIIANRLANGGQSWCETFERENSGTYNNQWMIVDYNKFVPGVKVRDGTLFVLEQVPGYIEFADVTNVLRTGYWPSYNIPYFETIFNMSGFNDELTDSSDYEAYEEDARSQIFRRDANKVYSLTDFQAIMRYNNFQNDPLSHGDAANQISSRFDLNSPDSQDYDAFGGVDSKVTSFSLVNQLLVIAQSGPTHDQEPPFQWSSANWSNIYPSIGMPNLYDFGWVNFTDISYNY", "length": 572 }, "evidence": [ { "id": "F1P0Z3", "url": "https://omabrowser.org/oma/group/F1P0Z3/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q8NHP8-1", "protein_name": "Putative aminopeptidase PLBD2", "gene_name": "PLBD2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVGQMYCYPGSHLARALTRALALALVLALLVGPFLSGLAGAIPAPGGRWARDGQVPPASRSRSVLLDVSAGQLLMVDGRHPDAVAWANLTNAIRETGWAFLELGTSGQYNDSLQAYAAGVVEAAVSEELIYMHWMNTVVNYCGPFEYEVGYCERLKSFLEANLEWMQEEMESNPDSPYWHQVRLTLLQLKGLEDSYEGRVSFPAGKFTIKPLGFLLLQLSGDLEDLELALNKTKIKPSLGSGSCSALIKLLPGQSDLLVAHNTWNNYQHMLRVIKKYWLQFREGPWGDYPLVPGNKLVFSSYPGTIFSCDDFYILGSGLVTLETTIGNKNPALWKYVRPRGCVLEWVRNIVANRLASDGATWADIFKRFNSGTYNNQWMIVDYKAFIPGGPSPGSRVLTILEQIPGMVVVADKTSELYQKTYWASYNIPSFETVFNASGLQALVAQYGDWFSYDGSPRAQIFRRNQSLVQDMDSMVRLMRYNDFLHDPLSLCKACNPQPNGENAISARSDLNPANGSYPFQALRQRSHGGIDVKVTSMSLARILSLLAASGPTWDQVPPFQWSTSPFSGLLHMGQPDLWKFAPVKVSWD", "length": 589 }, "evidence": [ { "id": "F1P0Z3", "url": "https://omabrowser.org/oma/group/F1P0Z3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "phospholipase activity", "id": "GO:0004620", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004620", "evidence": [ { "database": "UniProtKB", "id": "F1P0Z3", "url": "https://www.uniprot.org/uniprotkb/F1P0Z3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "lipid catabolic process", "id": "GO:0016042", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016042", "evidence": [ { "database": "UniProtKB", "id": "F1P0Z3", "url": "https://www.uniprot.org/uniprotkb/F1P0Z3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "F1P0Z3", "url": "https://www.uniprot.org/uniprotkb/F1P0Z3" } ], "pmid": "" }, { "name": "lysosome", "id": "GO:0005764", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005764", "evidence": [ { "database": "UniProtKB", "id": "F1P0Z3", "url": "https://www.uniprot.org/uniprotkb/F1P0Z3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 200, "end_pos": 202, "annotation": "n_glycosylation_sequon" }, { "start_pos": 404, "end_pos": 406, "annotation": "n_glycosylation_sequon" }, { "start_pos": 433, "end_pos": 435, "annotation": "n_glycosylation_sequon" }, { "start_pos": 483, "end_pos": 485, "annotation": "n_glycosylation_sequon" }, { "start_pos": 75, "end_pos": 77, "annotation": "n_glycosylation_sequon" }, { "start_pos": 79, "end_pos": 81, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1P0Z3-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 557, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1P0Z3-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1P0Z3" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 25, 521 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 200, "end_pos": 202 }, { "start_pos": 404, "end_pos": 406 }, { "start_pos": 433, "end_pos": 435 }, { "start_pos": 483, "end_pos": 485 }, { "start_pos": 75, "end_pos": 77 }, { "start_pos": 79, "end_pos": 81 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1NKW3-1", "uniprot_ac": "F1NKW3", "uniprot_id": "F1NKW3_CHICK", "mass": { "chemical_mass": 140777.0, "monoisotopic_mass": 140777.0 }, "refseq": {}, "gene_names": [ { "name": "MAP3K15", "type": "recommended", "evidence": [ { "id": "F1NKW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NKW3" } ] } ], "protein_names": [ { "name": "mitogen-activated protein kinase kinase kinase", "type": "recommended", "evidence": [ { "id": "F1NKW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NKW3/entry#names_and_taxonomy" } ] }, { "name": "2.7.11.25", "type": "synonym", "evidence": [ { "id": "F1NKW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NKW3/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NKW3", "url": "https://www.uniprot.org/uniprotkb/F1NKW3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MAP3K15", "url": "https://www.uniprot.org/uniprotkb/F1NKW3", "locus": { "chromosome": "1", "start_pos": 120382133, "end_pos": 120298659, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010002883", "url": "https://www.ensembl.org/id/ENSGALG00010002883" } ] } } ], "crossref": [ { "id": "F1NKW3", "url": "https://alphafold.ebi.ac.uk/entry/F1NKW3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000016426", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000016426", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd06624", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06624", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000719", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000719", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008271", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008271", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011009", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011009", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013761", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013761", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017441", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017441", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR025136", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025136", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043969", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043969", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046873", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046873", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XBQ3", "url": "https://www.orthodb.org/?gene=A0A8V0XBQ3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XEN8", "url": "https://www.orthodb.org/?gene=A0A8V0XEN8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NKW3", "url": "https://www.orthodb.org/?gene=F1NKW3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11584", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11584", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11584:SF363", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11584:SF363", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00069", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00069", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13281", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13281", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF19039", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19039", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF20302", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF20302", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "17989", "url": "https://www.rhea-db.org/rhea/17989", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "46608", "url": "https://www.rhea-db.org/rhea/46608", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0XBQ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XBQ3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XBQ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XBQ3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XEN8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEN8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XEN8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEN8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NKW3", "url": "https://www.uniprot.org/uniprotkb/F1NKW3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NKW3-1", "url": "https://www.uniprot.org/uniprotkb/F1NKW3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSDISKQPSLFYHLGVRESFDMANNVILYHGTDADTAQSLKDMVSQKNTASSGNYYFIPYIVTPSADYFCCESDAQRRASEYMQPSWDNILGPLCVPLVDRFISLLKDVHVTSCAYYKETLLNDIRKAREKYQGDELAKELARIKLRMDNTEVLTSDIVINLLLSYRDIQDYDAMVKLVETLEMLPTCDLADQHNIKFHYAFALNRRNNAGDREKALQVMLQVLQTCDHPAPDMFCLCGRIYKDMFLDSDCKDINSRDHAIEWYRKGFELQSTLYSGINLAVLLLAEGQQFESSMELRKIGVRLNSLLGRKGSLEKMNSYWDVGQFFSVSMLANDVSKAVQAAEKLFKLKPPVWYLKSLVQNLMLIQRFKKFTIEHSPKQERLTFWLDIIFEATKETTNGLRFPVLVIEPTKVYQPAYVSINNEEDERSLSLWHVSPTEMKQIHEWNFTASSIRGISISKFDERCCFLYVHANSDDFQIYFSTENQCTRFCGLVKEILSDAVGSTLELEGEIDGETLEYEYDYDEKGDRVVLGKGTYGIVYAGRDLSNQVRIAIKEIPERDSRYSQPLHEEIALHKYLKHRNVVQYLGSVSEDGYIKIFMEQVPGGSLSALLRSKWGPMKEPTIKFYTKQILEGLKYLHENQIVHRDIKGDNVLVNTYSGVVKISDFGTSKRLAGINPCTETFTGTLQYMAPEIIDKGPRGYGAPADIWSLGCTMIEMATGKPPFHELGEPQAAMFKVGMFKIHPEIPESLSAEAKAFILLCFEPDPFKRAAASDLLRDSFLKQVNKGKKSRIAFKPSDYNRNASLPLPIHGEQAGSSSSEHGSVSPDSDVQHDVFFERPKRSISEIQTRHPIAHLLSVPDEGLAPEDRSASPSTEDKDSGLFLLRKDSERRAILYKILKEEQNKVASNLQDCIAQSSEELRLSMAHIKQIIGILRDFIHSPEHRVMASTISKLKMDLDFDSTSINQIHLVLFGFQDAVNKVLRNHLIRPHWMFAMDNIIRRAVQAAVTILIPELQAHFEPASETEGGDKDCDEVEDSFRPSEQNGTEDAALTSGVSTLSSVVSHEAQQQLSLELGRLKQETIRLLEKLVQKEKEYQTLLQRSLEQKTQELHLLQLKLKPADWQWPASPLKENADPELTNWLKQQGADLDTIRRFAEEDYTLSTVLNDITKDDLRCLQLRGGLLCRIWNAILIHRQTANKSMEAEELLQWSKENEKGKIQKMFHVREKTQHIKH", "length": 1234, "header": "tr|F1NKW3-1|F1NKW3_CHICK Isoform 1 of mitogen-activated protein kinase kinase kinase OS=Gallus gallus OX=9031 GN=MAP3K15 PE=3 SV=3 CANONICAL=F1NKW3-1" }, "isoforms": [ { "isoform_ac": "A0A8V0XBQ3-1", "url": "https://www.uniprot.org/uniprotkb/F1NKW3/entry#A0A8V0XBQ3-1", "sequence": { "sequence": "MRTELKNKKFLVVTKQDVAVVDMSDISKQPSLFYHLGVRESFDMANNVILYHGTDADTAQSLKDMVSQKNTASSGNYYFIPYIVTPSADYFCCESDAQRRASEYMQPSWDNILGPLCVPLVDRFISLLKDVHVTSCAYYKETLLNDIRKAREKYQGDELAKELARIKLRMDNTEVLTSDIVINLLLSYRDIQDYDAMVKLVETLEMLPTCDLADQHNIKFHYAFALNRRNNAGDREKALQVMLQVLQTCDHPAPDMFCLCGRIYKDMFLDSDCKDINSRDHAIEWYRKGFELQSTLYSGINLAVLLLAEGQQFESSMELRKIGVRLNSLLGRKGSLEKMNSYWDVGQFFSVSMLANDVSKAVQAAEKLFKLKPPVWYLKSLVQNLMLIQRFKKFTIEHSPKQERLTFWLDIIFEATKETTNGLRFPVLVIEPTKVYQPAYVSINNEEDERSLSLWHVSPTEMKQIHEWNFTASSIRGISISKFDERCCFLYVHANSDDFQIYFSTENQCTRFCGLVKEILSDAVGSTLELEGEIDGETLEYEYDYDEKGDRVVLGKGTYGIVYAGRDLSNQVRIAIKEIPERDSRYSQPLHEEIALHKYLKHRNVVQYLGSVSEDGYIKIFMEQVPGGSLSALLRSKWGPMKEPTIKFYTKQILEGLKYLHENQIVHRDIKGDNVLVNTYSGVVKISDFGTSKRLAGINPCTETFTGTLQYMAPEIIDKGPRGYGAPADIWSLGCTMIEMATGKPPFHELGEPQAAMFKVGMFKIHPEIPESLSAEAKAFILLCFEPDPFKRAAASDLLRDSFLKQVNKGKKSRIAFKPSDYNRNASLPLPIHGEQAGSSSSEHGSVSPDSDVQHDVFFERPKRSISEIQTRHPIAHLLSVPDEGLAPEDRSASPSTEDKDSGLFLLRKDSERRAILYKILKEEQNKVASNLQDCIAQSSEELRLSMAHIKQIIGILRDFIHSPEHRVMASTISKLKMDLDFDSTSINQIHLVLFGFQDAVNKVLRNHLIRPHWMFAMDNIIRRAVQAAVTILIPELQAHFEPASETEGGDKDCDEVEDSFRPSEQNGTEDAALTSGVSTLSSVVSHEAQQQLSLELGRLKQETIRLLEKLVQKEKEYQTLLQRSLEQKTQELHLLQLKLKPADWQWPASPLKENADPELTNWLKQQGADLDTIRRFAEEDYTLSTVLNDITKDDLRCLQLRGGLLCRIWNAILIHRQTANKSMEAEG", "length": 1228, "header": "tr|A0A8V0XBQ3-1|F1NKW3_CHICK Computationally mapped isoform of mitogen-activated protein kinase kinase kinase OS=Gallus gallus OX=9031 GN=MAP3K15 PE=3 SV=1 CANONICAL=F1NKW3-1" }, "locus": { "chromosome": "1", "start_pos": 120370301, "end_pos": 120312959, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010006710.1", "url": "https://www.ensembl.org/id/ENSGALT00010006710.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010004101.1", "url": "https://www.ensembl.org/id/ENSGALP00010004101.1" } ] } }, { "isoform_ac": "A0A8V0XEN8-1", "url": "https://www.uniprot.org/uniprotkb/F1NKW3/entry#A0A8V0XEN8-1", "sequence": { "sequence": "MSDISKQPSLFYHLGVRESFDMANNVILYHGTDADTAQSLKDMVSQKNTASSGNYYFIPYIVTPSADYFCCESDAQRRASEYMQPSWDNILGPLCVPLVDRFISLLKDVHVTSCAYYKETLLNDIRKAREKYQGDELAKELARIKLRMDNTEVLTSDIVINLLLSYRDIQDYDAMVKLVETLEMLPTCDLADQHNIKFHYAFALNRRNNAGDREKALQVMLQVLQTCDHPAPDMFCLCGRIYKDMFLDSDCKDINSRDHAIEWYRKGFELQSTLYSGINLAVLLLAEGQQFESSMELRKIGVRLNSLLGRKGSLEKMNSYWDVGQFFSVSMLANDVSKAVQAAEKLFKLKPPVWYLKSLVQNLMLIQRFKKFTIEHSPKQERLTFWLDIIFEATKETTNGLRFPVLVIEPTKVYQPAYVSINNEEDERSLSLWHVSPTEMKQIHEWNFTASSIRGISISKFDERCCFLYVHANSDDFQIYFSTENQCTRFCGLVKEILSDAVGSTLELEGEIDGETLEYEYDYDEKGDRVVLGKGTYGIVYAGRDLSNQVRIAIKEIPERDSRYSQPLHEEIALHKYLKHRNVVQYLGSVSEDGYIKIFMEQVPGGSLSALLRSKWGPMKEPTIKFYTKQILEGLKYLHENQIVHRDIKGDNVLVNTYSGVVKISDFGTSKRLAGINPCTETFTGTLQYMAPEIIDKGPRGYGAPADIWSLGCTMIEMATGKPPFHELGEPQAAMFKVGMFKIHPEIPESLSAEAKAFILLCFEPDPFKRAAASDLLRDSFLKQVNKGKKSRIAFKPSDYNRNASLPLPIHGEQAGSSSSEHGSVSPDSDVQHDVFFERPKRSISEIQTRHPIAHLLSVPDEGLAPEDRSASPSTEDKDSGLFLLRKDSERRAILYKILKEEQNKVASNLQDCIAQSSEELRLSMAHIKQIIGILRDFIHSPEHRVMASTISKLKMDLDFDSTSINQIHLVLFGFQDAVNKVLRNHLIRPHWMFAMDNIIRRAVQAAVTILIPELQAHFEPASETEGGDKDCDEVEDSFRPSEQNGTEDAALTSGVSTLSSVVSHEAQQQLSLELGRLKQETIRLLEKLVQKEKEYQTLLQRSLEQKTQELHLLQLKLKPADWQWPASPLKENADPELTNWLKQQGADLDTIRRFAEEDYTLSTVLNDITKDDLRCLQLRGGLLCRIWNAILIHRQTANKSMEAEGFAQLHSSFDHQHNIQ", "length": 1221, "header": "tr|A0A8V0XEN8-1|F1NKW3_CHICK Computationally mapped isoform of mitogen-activated protein kinase kinase kinase OS=Gallus gallus OX=9031 GN=MAP3K15 PE=3 SV=1 CANONICAL=F1NKW3-1" }, "locus": { "chromosome": "1", "start_pos": 120370448, "end_pos": 120316249, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010006721.1", "url": "https://www.ensembl.org/id/ENSGALT00010006721.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010004104.1", "url": "https://www.ensembl.org/id/ENSGALP00010004104.1" } ] } }, { "isoform_ac": "F1NKW3-1", "url": "https://www.uniprot.org/uniprotkb/F1NKW3/entry#F1NKW3-1", "sequence": { "sequence": "MSDISKQPSLFYHLGVRESFDMANNVILYHGTDADTAQSLKDMVSQKNTASSGNYYFIPYIVTPSADYFCCESDAQRRASEYMQPSWDNILGPLCVPLVDRFISLLKDVHVTSCAYYKETLLNDIRKAREKYQGDELAKELARIKLRMDNTEVLTSDIVINLLLSYRDIQDYDAMVKLVETLEMLPTCDLADQHNIKFHYAFALNRRNNAGDREKALQVMLQVLQTCDHPAPDMFCLCGRIYKDMFLDSDCKDINSRDHAIEWYRKGFELQSTLYSGINLAVLLLAEGQQFESSMELRKIGVRLNSLLGRKGSLEKMNSYWDVGQFFSVSMLANDVSKAVQAAEKLFKLKPPVWYLKSLVQNLMLIQRFKKFTIEHSPKQERLTFWLDIIFEATKETTNGLRFPVLVIEPTKVYQPAYVSINNEEDERSLSLWHVSPTEMKQIHEWNFTASSIRGISISKFDERCCFLYVHANSDDFQIYFSTENQCTRFCGLVKEILSDAVGSTLELEGEIDGETLEYEYDYDEKGDRVVLGKGTYGIVYAGRDLSNQVRIAIKEIPERDSRYSQPLHEEIALHKYLKHRNVVQYLGSVSEDGYIKIFMEQVPGGSLSALLRSKWGPMKEPTIKFYTKQILEGLKYLHENQIVHRDIKGDNVLVNTYSGVVKISDFGTSKRLAGINPCTETFTGTLQYMAPEIIDKGPRGYGAPADIWSLGCTMIEMATGKPPFHELGEPQAAMFKVGMFKIHPEIPESLSAEAKAFILLCFEPDPFKRAAASDLLRDSFLKQVNKGKKSRIAFKPSDYNRNASLPLPIHGEQAGSSSSEHGSVSPDSDVQHDVFFERPKRSISEIQTRHPIAHLLSVPDEGLAPEDRSASPSTEDKDSGLFLLRKDSERRAILYKILKEEQNKVASNLQDCIAQSSEELRLSMAHIKQIIGILRDFIHSPEHRVMASTISKLKMDLDFDSTSINQIHLVLFGFQDAVNKVLRNHLIRPHWMFAMDNIIRRAVQAAVTILIPELQAHFEPASETEGGDKDCDEVEDSFRPSEQNGTEDAALTSGVSTLSSVVSHEAQQQLSLELGRLKQETIRLLEKLVQKEKEYQTLLQRSLEQKTQELHLLQLKLKPADWQWPASPLKENADPELTNWLKQQGADLDTIRRFAEEDYTLSTVLNDITKDDLRCLQLRGGLLCRIWNAILIHRQTANKSMEAEELLQWSKENEKGKIQKMFHVREKTQHIKH", "length": 1234, "header": "tr|F1NKW3-1|F1NKW3_CHICK Isoform 1 of mitogen-activated protein kinase kinase kinase OS=Gallus gallus OX=9031 GN=MAP3K15 PE=3 SV=3 CANONICAL=F1NKW3-1" }, "locus": { "chromosome": "1", "start_pos": 120382013, "end_pos": 120316249, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010006731.1", "url": "https://www.ensembl.org/id/ENSGALT00010006731.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010004106.1", "url": "https://www.ensembl.org/id/ENSGALP00010004106.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "F1NKW3", "url": "https://www.uniprot.org/uniprotkb/F1NKW3" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "F1NKW3", "url": "https://www.uniprot.org/uniprotkb/F1NKW3" } ], "pmid": "" }, { "name": "MAP kinase kinase kinase activity", "id": "GO:0004709", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004709", "evidence": [ { "database": "UniProtKB", "id": "F1NKW3", "url": "https://www.uniprot.org/uniprotkb/F1NKW3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "JNK cascade", "id": "GO:0007254", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007254", "evidence": [ { "database": "UniProtKB", "id": "F1NKW3", "url": "https://www.uniprot.org/uniprotkb/F1NKW3" } ], "pmid": "" }, { "name": "p38MAPK cascade", "id": "GO:0038066", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038066", "evidence": [ { "database": "UniProtKB", "id": "F1NKW3", "url": "https://www.uniprot.org/uniprotkb/F1NKW3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1045, "end_pos": 1047, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1199, "end_pos": 1201, "annotation": "n_glycosylation_sequon" }, { "start_pos": 447, "end_pos": 449, "annotation": "n_glycosylation_sequon" }, { "start_pos": 803, "end_pos": 805, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "17989", "name": "", "equation": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q6U1I9-1", "A0A8V0XNJ2-1", "A0A8V0ZUL0-1", "A0A8V0ZT63-1", "A0A8V1ACW2-1", "A0A8V0Z1X0-1", "A0A8V0YHN2-1", "A0A8V0YMN5-1", "A0A8V0Z807-1", "A0A8V0Z930-1", "A0A8V0YFR6-1", "A0A1D5P0M9-1", "A0A8V0ZBN6-1", "A0A3Q2U9U9-1", "A0A8V0YXZ5-1", "A0A8V0ZSP4-1", "A0A8V0ZXQ9-1", "A0A8V0ZZV3-1", "A0A8V1ADF0-1", "A0A8V0ZFT3-1", "A0A8V0ZA45-1", "A0A8V0ZB33-1", "A0A8V0ZD70-1", "A0A8V0Z8T4-1", "R4GIN8-1", "A0A8V0ZK64-1", "A0A8V0ZC16-1", "A0A8V0ZWW1-1", "E1BY69-1", "A0A8V0ZDW9-1", "A0A8V0ZKA2-1", "A0A3Q3B2F1-1", "F1P356-1", "A0A8V1AHA8-1", "Q8QFP8-1", "F1P011-1", "A0A8V0YKK3-1", "A0A1D5NWT4-1", "A0A1D5PMQ7-1", "E1BWA3-1", "F1NVF2-1", "A0A1D5PXN4-1", "A0A3Q2TY19-1", "A0A3Q2U592-1", "A0A8V0XCV5-1", "A0A1D5P8A9-1", "A0A1D5PMG2-1", "A0A8V0X1Q7-1", "A0A8V0Y935-1", "A0A8V0YM96-1", "A0A8V0YF83-1", "A0A8V0YJP9-1", "A0A8V1AKW4-1", "A0A8V0ZSB4-1", "F1NBT0-1", "P18652-1", "P21868-1", "P21869-1", "P53666-1", "P79996-1", "Q5F3W3-1", "Q5ZJS0-1", "Q5ZKN1-1", "Q5ZLL1-1", "A0A8V0XCS0-1", "A0A8V0XNK8-1", "A0A8V0XLV6-1", "A0A8V0XDR5-1", "E1BYH2-1", "E1BQN6-1", "A0A8V0XU71-1", "Q5ZJH6-1", "A0A8V0Y3D1-1", "A0A8V0Y7C3-1", "A0A8V0YCY4-1", "A0A8V0YIV6-1", "A0A8V0YK18-1", "A0A8V0YM22-1", "A0A8V0YTN5-1", "A0A8V0YTP2-1", "Q5F3L1-1", "A0A8V0Y3L2-1", "A0A8V0YCY8-1", "A0A8V0Y9Q1-1", "A0A8V0ZD48-1", "A0A8V0ZD60-1", "A0A8V0ZBZ2-1", "A0A8V0Z9J0-1", "A0A8V1ABF3-1", "Q8AYC9-1", "A0A8V0Z927-1", "A0A8V1A2T9-1", "Q5ZKI0-1", "Q7T0B1-1", "P10741-1", "A0A8V0YFH4-1", "E1C848-1", "A0A8V0X8M1-1", "E1BW33-1", "A0A8V0Z283-1", "A0A8V0Z157-1", "A0A3Q2U4X3-1", "A0A8V0XW11-1", "E1BUG0-1", "A0A8V1ABP4-1", "A0A8V1AJA4-1", "A0A8V1AEH4-1", "F1NJH1-1", "A0A8V1AMK5-1", "A0A3Q2TRY2-1", "A0A8V0X3D6-1", "A0A1D5PD64-1", "A0A8V0XQ97-1", "R4GJB8-1", "A0A8V0X5Z8-1", "A0A8V0XG21-1", "A0A8V0XB58-1", "A0A8V0XMX8-1", "A0A8V0XQS0-1", "A0A8V0XW29-1", "A0A8V0Y074-1", "A0A8V0XXB8-1", "A0A8V0XQ14-1", "A0A8V0XMT1-1", "A0A8V0Y457-1", "A0A8V0Y823-1", "A0A8V0Y4L8-1", "A0A8V0XND6-1", "A0A8V0YZ74-1", "A0A8V0YTI1-1", "A0A8V0YLV1-1", "A0A8V0Z2E3-1", "A0A8V0YCV9-1", "A0A8V0YSH3-1", "A0A8V0YYX2-1", "A0A8V0YZY4-1", "Q5ZIU3-1", "A0A8V0YZK0-1", "A0A8V0ZKM9-1", "A0A8V0ZWC7-1", "A0A8V1A1Y7-1", "A0A8V1A069-1", "A0A8V0ZI32-1", "A0A8V0ZH91-1", "E1BQV7-1", "A0A8V0ZRX1-1", "A0A8V0ZUU9-1", "A0A8V1A0Y8-1", "A0A8V1A7E9-1", "A0A8V1A7E0-1", "A0A8V1A3T8-1", "A0A8V1A9S5-1", "A0A8V1A7M0-1", 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"id": "A0A1D5NWT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NWT4" } ] } ] }, { "uniprot_ac": "A0A1D5P0M9", "gene_name": "MAP3K13", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5P0M9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P0M9" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A1D5P0M9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P0M9" } ] } ] }, { "uniprot_ac": "A0A1D5P517", "gene_name": "PLK3", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5P517", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P517" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0A1D5P517", "database": "UniProtKB", "url": 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O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q2UI62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UI62" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A3Q2UI62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UI62" } ] } ] }, { "uniprot_ac": "A0A3Q3A664", "gene_name": "CDK17", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q3A664", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3A664" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A3Q3A664", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3A664" } ] } ] }, { "uniprot_ac": "A0A3Q3AAD7", "gene_name": "STK35", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q3AAD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3AAD7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q3AAD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3AAD7" } ] } ] }, { "uniprot_ac": "A0A3Q3B2F1", "gene_name": "PKN3", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q3B2F1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3B2F1" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A3Q3B2F1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3B2F1" } ] } ] }, { "uniprot_ac": "A0A8V0X1Q7", "gene_name": "MELK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X1Q7", "database": "UniProtKB", "url": 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"database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X2Y2" } ] } ] }, { "uniprot_ac": "A0A8V0X3D6", "gene_name": "LOC100858386", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X3D6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X3D6" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0X3D6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X3D6" } ] } ] }, { "uniprot_ac": "A0A8V0X4P0", "gene_name": "CDKL5", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X4P0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X4P0" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0X4P0", "database": "UniProtKB", "url": 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"uniprot_ac": "A0A8V0X6T4", "gene_name": "LOC107050692", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X6T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X6T4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0X6T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X6T4" } ] } ] }, { "uniprot_ac": "A0A8V0X7R2", "gene_name": "SBK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X7R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X7R2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0X7R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X7R2" } ] } ] }, { "uniprot_ac": "A0A8V0X8M1", "gene_name": "TRIO", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X8M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X8M1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0X8M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X8M1" } ] } ] }, { "uniprot_ac": "A0A8V0XAH9", "gene_name": "NEK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XAH9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XAH9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XAH9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XAH9" } ] } ] }, { "uniprot_ac": "A0A8V0XB58", "gene_name": "CAMK2D", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XB58", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XB58" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V0XB58", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XB58" } ] } ] }, { "uniprot_ac": "A0A8V0XBZ0", "gene_name": "STK32C", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XBZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XBZ0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XBZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XBZ0" } ] } ] }, { "uniprot_ac": "A0A8V0XCS0", "gene_name": "PRKG2", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XCS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCS0" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "A0A8V0XCS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCS0" } ] } ] }, { "uniprot_ac": "A0A8V0XCV5", "gene_name": "MAP3K7", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XCV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCV5" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0XCV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCV5" } ] } ] }, { "uniprot_ac": "A0A8V0XCY6", "gene_name": "TTK", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XCY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCY6" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V0XCY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCY6" } ] } ] }, { "uniprot_ac": "A0A8V0XDR5", "gene_name": "IRAK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XDR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XDR5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XDR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XDR5" } ] } ] }, { "uniprot_ac": "A0A8V0XE48", "gene_name": "ROCK2", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XE48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XE48" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "A0A8V0XE48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XE48" } ] } ] }, { "uniprot_ac": "A0A8V0XEA3", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XEA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEA3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XEA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEA3" } ] } ] }, { "uniprot_ac": "A0A8V0XFW1", "gene_name": "SGK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XFW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XFW1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XFW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XFW1" } ] } ] }, { "uniprot_ac": "A0A8V0XFX2", "gene_name": "NEK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XFX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XFX2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XFX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XFX2" } ] } ] }, { "uniprot_ac": "A0A8V0XG21", "gene_name": "LOC107050335", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XG21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XG21" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XG21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XG21" } ] } ] }, { "uniprot_ac": "A0A8V0XI18", "gene_name": "ATM", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XI18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XI18" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XI18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XI18" } ] } ] }, { "uniprot_ac": "A0A8V0XKG0", "gene_name": "NEK9", "activity": [ { "ec_number": "2.7.11.38", "activity": "L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XKG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XKG0" } ] }, { "ec_number": "2.7.11.38", "activity": "", "evidence": [ { "id": "A0A8V0XKG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XKG0" } ] } ] }, { "uniprot_ac": "A0A8V0XLV6", "gene_name": "MAPK10", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XLV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XLV6" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0XLV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XLV6" } ] } ] }, { "uniprot_ac": "A0A8V0XMT1", "gene_name": "MOS", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XMT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMT1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XMT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMT1" } ] } ] }, { "uniprot_ac": "A0A8V0XMX8", "gene_name": "MASTL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XMX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMX8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XMX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMX8" } ] } ] }, { "uniprot_ac": "A0A8V0XND6", "gene_name": "RIOK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XND6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XND6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XND6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XND6" } ] } ] }, { "uniprot_ac": "A0A8V0XNJ2", "gene_name": "CDK8", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XNJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNJ2" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XNJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNJ2" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0XNJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNJ2" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A8V0XNJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNJ2" } ] } ] }, { "uniprot_ac": "A0A8V0XNK8", "gene_name": "PRKCQ", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XNK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNK8" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V0XNK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNK8" } ] } ] }, { "uniprot_ac": "A0A8V0XQ14", "gene_name": "PLK4", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XQ14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ14" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0A8V0XQ14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ14" } ] } ] }, { "uniprot_ac": "A0A8V0XQ97", "gene_name": "CDK14", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XQ97", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ97" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0XQ97", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ97" } ] } ] }, { "uniprot_ac": "A0A8V0XQQ4", "gene_name": "NME7", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQQ4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQQ4" } ] } ] }, { "uniprot_ac": "A0A8V0XQS0", "gene_name": "STK24", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XQS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQS0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XQS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQS0" } ] } ] }, { "uniprot_ac": "A0A8V0XS42", "gene_name": "MAP3K4", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XS42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XS42" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0XS42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XS42" } ] } ] }, { "uniprot_ac": "A0A8V0XU71", "gene_name": "MYO3A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XU71", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XU71" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XU71", "database": "UniProtKB", "url": 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"uniprot_ac": "A0A8V0XW11", "gene_name": "RPS6KA2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XW11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XW11" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XW11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XW11" } ] } ] }, { "uniprot_ac": "A0A8V0XW29", "gene_name": "CDKL2", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XW29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XW29" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0XW29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XW29" } ] } ] }, { "uniprot_ac": "A0A8V0XXB8", "gene_name": "MAPK15", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XXB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XXB8" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0XXB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XXB8" } ] } ] }, { "uniprot_ac": "A0A8V0Y074", "gene_name": "NEK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y074", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y074" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y074", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y074" } ] } ] }, { "uniprot_ac": "A0A8V0Y241", "gene_name": "LOC426385", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y241", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y241" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y241", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y241" } ] } ] }, { "uniprot_ac": "A0A8V0Y2I5", "gene_name": "CDK7", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] }, { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] } ] }, { "uniprot_ac": "A0A8V0Y3D1", "gene_name": "LRRK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y3D1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y3D1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y3D1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y3D1" } ] } ] }, { "uniprot_ac": "A0A8V0Y3L2", "gene_name": "MLK4", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y3L2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y3L2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0Y3L2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y3L2" } ] } ] }, { "uniprot_ac": "A0A8V0Y457", "gene_name": "PRPF4B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y457", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y457" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y457", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y457" } ] } ] }, { "uniprot_ac": "A0A8V0Y4L8", "gene_name": "HUNK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y4L8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y4L8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y4L8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y4L8" } ] } ] }, { "uniprot_ac": "A0A8V0Y6K1", "gene_name": "MAK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y6K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y6K1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y6K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y6K1" } ] } ] }, { "uniprot_ac": "A0A8V0Y7C3", "gene_name": "DAPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y7C3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y7C3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y7C3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y7C3" } ] } ] }, { "uniprot_ac": "A0A8V0Y823", "gene_name": "SRPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y823", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y823" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y823", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y823" } ] } ] }, { "uniprot_ac": "A0A8V0Y8X9", "gene_name": "PRKACA", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y8X9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y8X9" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "A0A8V0Y8X9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y8X9" } ] } ] }, { "uniprot_ac": "A0A8V0Y935", "gene_name": "MAST4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y935", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y935" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y935", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y935" } ] } ] }, { "uniprot_ac": "A0A8V0Y955", "gene_name": "PAK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y955", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y955" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y955", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y955" } ] } ] }, { "uniprot_ac": "A0A8V0Y9Q1", "gene_name": "LOC107055388", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y9Q1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9Q1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y9Q1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9Q1" } ] } ] }, { "uniprot_ac": "A0A8V0YCV9", "gene_name": "SIK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YCV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCV9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YCV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCV9" } ] } ] }, { "uniprot_ac": "A0A8V0YCY4", "gene_name": "AURKB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YCY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCY4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YCY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCY4" } ] } ] }, { "uniprot_ac": "A0A8V0YCY8", "gene_name": "RIOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YCY8", "database": "UniProtKB", "url": 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"ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YF83", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF83" } ] } ] }, { "uniprot_ac": "A0A8V0YFH4", "gene_name": "NRK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YFH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFH4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YFH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFH4" } ] } ] }, { "uniprot_ac": "A0A8V0YFL1", "gene_name": "CDK19", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YFL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFL1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": 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"https://www.uniprot.org/uniprotkb/A0A8V0YFR6" } ] } ] }, { "uniprot_ac": "A0A8V0YGW2", "gene_name": "STK32B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YGW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGW2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YGW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGW2" } ] } ] }, { "uniprot_ac": "A0A8V0YHH2", "gene_name": "STK38L", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YHH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHH2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YHH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHH2" } ] } ] }, { "uniprot_ac": "A0A8V0YHN2", "gene_name": "RPS6KA1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YHN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHN2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YHN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHN2" } ] } ] }, { "uniprot_ac": "A0A8V0YIV6", "gene_name": "DYRK1A", "activity": [ { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] }, { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] } ] }, { "uniprot_ac": "A0A8V0YJP9", "gene_name": "RIOK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YJP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJP9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YJP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJP9" } ] } ] }, { "uniprot_ac": "A0A8V0YK18", "gene_name": "CDC42BPB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YK18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK18" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YK18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK18" } ] } ] }, { "uniprot_ac": "A0A8V0YKK3", "gene_name": "MAP4K4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YKK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKK3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YKK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKK3" } ] } ] }, { "uniprot_ac": "A0A8V0YLV1", "gene_name": "MARK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YLV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLV1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YLV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLV1" } ] } ] }, { "uniprot_ac": "A0A8V0YM22", "gene_name": "MYO3AL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YM22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM22" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YM22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM22" } ] } ] }, { "uniprot_ac": "A0A8V0YM96", "gene_name": "STK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YM96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM96" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YM96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM96" } ] } ] }, { "uniprot_ac": "A0A8V0YMB3", "gene_name": "STK32A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YMB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMB3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YMB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMB3" } ] } ] }, { "uniprot_ac": "A0A8V0YMN5", "gene_name": "BRAF", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YMN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMN5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YMN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMN5" } ] } ] }, { "uniprot_ac": "A0A8V0YNI5", "gene_name": "NIM1K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YNI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNI5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YNI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNI5" } ] } ] }, { "uniprot_ac": "A0A8V0YRC9", "gene_name": "TNK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YRC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRC9" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YRC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRC9" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0YRC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRC9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YRC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRC9" } ] } ] }, { "uniprot_ac": "A0A8V0YRN4", "gene_name": "GAK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YRN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRN4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YRN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRN4" } ] } ] }, { "uniprot_ac": "A0A8V0YSH3", "gene_name": "RPS6KA6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YSH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSH3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YSH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSH3" } ] } ] }, { "uniprot_ac": "A0A8V0YTI1", "gene_name": "TSSK6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTI1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTI1" } ] } ] }, { "uniprot_ac": "A0A8V0YTL9", "gene_name": "VRK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTL9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTL9" } ] } ] }, { "uniprot_ac": "A0A8V0YTN5", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTN5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTN5" } ] } ] }, { "uniprot_ac": "A0A8V0YTP2", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTP2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTP2" } ] } ] }, { "uniprot_ac": "A0A8V0YXZ5", "gene_name": "CDC42BPA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YXZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXZ5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YXZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXZ5" } ] } ] }, { "uniprot_ac": "A0A8V0YYX2", "gene_name": "PAK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YYX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYX2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YYX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYX2" } ] } ] }, { "uniprot_ac": "A0A8V0YYZ3", "gene_name": "SPEG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YYZ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYZ3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YYZ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYZ3" } ] } ] }, { "uniprot_ac": "A0A8V0YZ74", "gene_name": "MAP2K5", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZ74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZ74" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V0YZ74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZ74" } ] } ] }, { "uniprot_ac": "A0A8V0YZF2", "gene_name": "PAK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZF2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YZF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZF2" } ] } ] }, { "uniprot_ac": "A0A8V0YZK0", "gene_name": "MAP3K6", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZK0" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0YZK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZK0" } ] } ] }, { "uniprot_ac": "A0A8V0YZM1", "gene_name": "MOK", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZM1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0YZM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZM1" } ] }, { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZM1" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0YZM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZM1" } ] } ] }, { "uniprot_ac": "A0A8V0YZV9", "gene_name": "ATR", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZV9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YZV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZV9" } ] } ] }, { "uniprot_ac": "A0A8V0YZY4", "gene_name": "SBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZY4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YZY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZY4" } ] } ] }, { "uniprot_ac": "A0A8V0Z124", "gene_name": "VRK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z124", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z124" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z124", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z124" } ] } ] }, { "uniprot_ac": "A0A8V0Z157", "gene_name": "MARK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z157", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z157" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z157", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z157" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A8V0Z157", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z157" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z157", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z157" } ] } ] }, { "uniprot_ac": "A0A8V0Z1X0", "gene_name": "MAP4K3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z1X0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1X0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z1X0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1X0" } ] } ] }, { "uniprot_ac": "A0A8V0Z283", "gene_name": "MARK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z283", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z283" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z283", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z283" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A8V0Z283", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z283" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z283", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z283" } ] } ] }, { "uniprot_ac": "A0A8V0Z2E3", "gene_name": "PDIK1L", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z2E3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2E3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z2E3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2E3" } ] } ] }, { "uniprot_ac": "A0A8V0Z2Z3", "gene_name": "AAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z2Z3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2Z3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z2Z3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2Z3" } ] } ] }, { "uniprot_ac": "A0A8V0Z466", "gene_name": "MAP3K19", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z466", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z466" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z466", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z466" } ] } ] }, { "uniprot_ac": "A0A8V0Z6K4", "gene_name": "PIK3R4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z6K4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6K4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z6K4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6K4" } ] } ] }, { "uniprot_ac": "A0A8V0Z6T1", "gene_name": "ERN2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z6T1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6T1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z6T1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6T1" } ] } ] }, { "uniprot_ac": "A0A8V0Z807", "gene_name": "NEK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z807", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z807" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z807", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z807" } ] } ] }, { "uniprot_ac": "A0A8V0Z8G2", "gene_name": "TTBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z8G2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8G2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z8G2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8G2" } ] } ] }, { "uniprot_ac": "A0A8V0Z8T4", "gene_name": "RPS6KC1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z8T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8T4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z8T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8T4" } ] } ] }, { "uniprot_ac": "A0A8V0Z927", "gene_name": "PINK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z927", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z927" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z927", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z927" } ] } ] }, { "uniprot_ac": "A0A8V0Z930", "gene_name": "CAMK2B", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z930", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z930" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V0Z930", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z930" } ] } ] }, { "uniprot_ac": "A0A8V0Z9J0", "gene_name": "CIT", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z9J0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9J0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z9J0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9J0" } ] } ] }, { "uniprot_ac": "A0A8V0ZA06", "gene_name": "CDKL1", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZA06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA06" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0ZA06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA06" } ] } ] }, { "uniprot_ac": "A0A8V0ZA45", "gene_name": "MAP4K5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZA45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA45" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZA45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA45" } ] } ] }, { "uniprot_ac": "A0A8V0ZB33", "gene_name": "CAMK2G", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZB33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB33" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V0ZB33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB33" } ] } ] }, { "uniprot_ac": "A0A8V0ZB38", "gene_name": "CIITA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZB38", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB38" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZB38", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB38" } ] } ] }, { "uniprot_ac": "A0A8V0ZBN6", "gene_name": "MAP2K1", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZBN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBN6" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V0ZBN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBN6" } ] } ] }, { "uniprot_ac": "A0A8V0ZBZ2", "gene_name": "MAP3K9", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZBZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBZ2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0ZBZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBZ2" } ] } ] }, { "uniprot_ac": "A0A8V0ZC16", "gene_name": "KALRN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZC16", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC16" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZC16", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC16" } ] } ] }, { "uniprot_ac": "A0A8V0ZD40", "gene_name": "CDC2L1", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD40" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD40" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A8V0ZD40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD40" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0ZD40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD40" } ] } ] }, { "uniprot_ac": "A0A8V0ZD48", "gene_name": "PRKCE", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD48" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V0ZD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD48" } ] } ] }, { "uniprot_ac": "A0A8V0ZD60", "gene_name": "STK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD60" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZD60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD60" } ] } ] }, { "uniprot_ac": "A0A8V0ZD70", "gene_name": "DCLK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD70" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZD70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD70" } ] } ] }, { "uniprot_ac": "A0A8V0ZDW9", "gene_name": "NEK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZDW9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDW9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZDW9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDW9" } ] } ] }, { "uniprot_ac": "A0A8V0ZFM2", "gene_name": "LMTK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZFM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFM2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZFM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFM2" } ] } ] }, { "uniprot_ac": "A0A8V0ZFP1", "gene_name": "TTBK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZFP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFP1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZFP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFP1" } ] } ] }, { "uniprot_ac": "A0A8V0ZFT3", "gene_name": "LRRK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZFT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFT3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZFT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFT3" } ] } ] }, { "uniprot_ac": "A0A8V0ZGY3", "gene_name": "HIPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZGY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGY3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZGY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGY3" } ] } ] }, { "uniprot_ac": "A0A8V0ZH91", "gene_name": "WNK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": 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1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,5-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZMK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMK1" } ] }, { "ec_number": "2.7.1.150", "activity": "", "evidence": [ { "id": "A0A8V0ZMK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMK1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZMK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMK1" } ] } ] }, { "uniprot_ac": "A0A8V0ZNP7", "gene_name": "SGK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZNP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNP7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZNP7", "database": 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"https://www.uniprot.org/uniprotkb/A0A8V0ZQJ2" } ] } ] }, { "uniprot_ac": "A0A8V0ZQT5", "gene_name": "SLC13A3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZQT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQT5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZQT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQT5" } ] } ] }, { "uniprot_ac": "A0A8V0ZRX1", "gene_name": "SETD6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZRX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRX1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZRX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRX1" } ] }, { 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O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZSP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSP4" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V0ZSP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSP4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZSP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSP4" } ] } ] }, { "uniprot_ac": "A0A8V0ZT63", "gene_name": "STK25", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZT63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT63" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZT63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT63" } ] } ] }, { "uniprot_ac": "A0A8V0ZUC6", 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"activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZUU8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUU8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZUU8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUU8" } ] } ] }, { "uniprot_ac": "A0A8V0ZUU9", "gene_name": "MKNK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZUU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUU9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZUU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUU9" } ] } ] }, { "uniprot_ac": "A0A8V0ZWC7", "gene_name": "EIF2AK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZWC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWC7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZWC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWC7" } ] } ] }, { "uniprot_ac": "A0A8V0ZWW1", "gene_name": "MAP3K12", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZWW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWW1" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0ZWW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWW1" } ] } ] }, { "uniprot_ac": "A0A8V0ZXQ9", "gene_name": "PRKG1", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZXQ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXQ9" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "A0A8V0ZXQ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXQ9" } ] } ] }, { "uniprot_ac": "A0A8V0ZYU6", "gene_name": "TNNI3K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZYU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZYU6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZYU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZYU6" } ] } ] }, { "uniprot_ac": "A0A8V0ZZE4", "gene_name": "OBSCN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZZE4", "database": "UniProtKB", "url": 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"ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZZV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZV3" } ] } ] }, { "uniprot_ac": "A0A8V1A069", "gene_name": "TESK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A069", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A069" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V1A069", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A069" } ] } ] }, { "uniprot_ac": "A0A8V1A0W4", "gene_name": "ULK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A0W4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0W4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A0W4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0W4" } ] } ] }, { "uniprot_ac": "A0A8V1A0Y8", "gene_name": "MAST2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A0Y8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0Y8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A0Y8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0Y8" } ] } ] }, { "uniprot_ac": "A0A8V1A1P3", "gene_name": "SRPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A1P3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1P3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A1P3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1P3" } ] } ] }, { "uniprot_ac": "A0A8V1A1Y7", "gene_name": "CDK2", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A1Y7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1Y7" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V1A1Y7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1Y7" } ] } ] }, { "uniprot_ac": "A0A8V1A2T9", "gene_name": "MAP3K14", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A2T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2T9" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V1A2T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2T9" } ] } ] }, { "uniprot_ac": "A0A8V1A3T8", "gene_name": "MAST3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A3T8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3T8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A3T8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3T8" } ] } ] }, { "uniprot_ac": "A0A8V1A4A1", "gene_name": "CAMKK2", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4A1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4A1" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V1A4A1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4A1" } ] } ] }, { "uniprot_ac": "A0A8V1A4J8", "gene_name": "MAPKAPK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4J8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4J8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A4J8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4J8" } ] } ] }, { "uniprot_ac": "A0A8V1A4Q4", "gene_name": "MAPK3", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4Q4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4Q4" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V1A4Q4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4Q4" } ] } ] }, { "uniprot_ac": "A0A8V1A4V7", "gene_name": "HIPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4V7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4V7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A4V7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4V7" } ] } ] }, { "uniprot_ac": "A0A8V1A513", "gene_name": "DAPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A513", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A513" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A513", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A513" } ] } ] }, { "uniprot_ac": "A0A8V1A675", "gene_name": "CSNK1G2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A675", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A675" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A675", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A675" } ] } ] }, { "uniprot_ac": "A0A8V1A7E0", "gene_name": "DYRK3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7E0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E0" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V1A7E0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E0" } ] } ] }, { "uniprot_ac": "A0A8V1A7E9", "gene_name": "SIK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7E9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A7E9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E9" } ] } ] }, { "uniprot_ac": "A0A8V1A7M0", "gene_name": "STK39", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7M0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7M0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A7M0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7M0" } ] } ] }, { "uniprot_ac": "A0A8V1A7P9", "gene_name": "DCAF1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A7P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P9" } ] } ] }, { "uniprot_ac": "A0A8V1A9S5", "gene_name": "NUAK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A9S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9S5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A9S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9S5" } ] } ] }, { "uniprot_ac": "A0A8V1ABF3", "gene_name": "PRKAA2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] } ] }, { "uniprot_ac": "A0A8V1ABP4", "gene_name": "DSTYK", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABP4" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V1ABP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABP4" } ] } ] }, { "uniprot_ac": "A0A8V1ABR8", "gene_name": "CAMK4L", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABR8" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V1ABR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABR8" } ] } ] }, { "uniprot_ac": "A0A8V1AC40", "gene_name": "CDK18", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AC40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC40" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V1AC40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC40" } ] } ] }, { "uniprot_ac": "A0A8V1ACB5", "gene_name": "MAPK13", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACB5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V1ACB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACB5" } ] } ] }, { "uniprot_ac": "A0A8V1ACF6", "gene_name": "PIM1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACF6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ACF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACF6" } ] } ] }, { "uniprot_ac": "A0A8V1ACK0", "gene_name": "MAPKAPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACK0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ACK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACK0" } ] } ] }, { "uniprot_ac": "A0A8V1ACW2", "gene_name": "WNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACW2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ACW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACW2" } ] } ] }, { "uniprot_ac": "A0A8V1ADF0", "gene_name": "MAP2K2", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ADF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADF0" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V1ADF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADF0" } ] } ] }, { "uniprot_ac": "A0A8V1ADN9", "gene_name": "NLK", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ADN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADN9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V1ADN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADN9" } ] } ] }, { "uniprot_ac": "A0A8V1ADT4", "gene_name": "MKNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ADT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADT4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ADT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADT4" } ] } ] }, { "uniprot_ac": "A0A8V1AE45", "gene_name": "ERN1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AE45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE45" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AE45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE45" } ] } ] }, { "uniprot_ac": "A0A8V1AEH4", "gene_name": "STK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AEH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEH4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AEH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEH4" } ] } ] }, { "uniprot_ac": "A0A8V1AFS4", "gene_name": "STKLD1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AFS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFS4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AFS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFS4" } ] } ] }, { "uniprot_ac": "A0A8V1AG70", "gene_name": "LOC100857512", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AG70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AG70" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AG70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AG70" } ] } ] }, { "uniprot_ac": "A0A8V1AH12", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AH12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH12" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AH12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH12" } ] } ] }, { "uniprot_ac": "A0A8V1AHA8", "gene_name": "NEK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AHA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHA8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AHA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHA8" } ] } ] }, { "uniprot_ac": "A0A8V1AIY7", "gene_name": "AATK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AIY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIY7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AIY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIY7" } ] } ] }, { "uniprot_ac": "A0A8V1AJA4", "gene_name": "RPS6KB1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AJA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJA4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AJA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJA4" } ] } ] }, { "uniprot_ac": "A0A8V1AKW4", "gene_name": "MAP2K4", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AKW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKW4" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V1AKW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKW4" } ] } ] }, { "uniprot_ac": "A0A8V1AM12", "gene_name": "GSG2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AM12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM12" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AM12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM12" } ] } ] }, { "uniprot_ac": "A0A8V1AMK5", "gene_name": "PRKCA", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AMK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMK5" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V1AMK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMK5" } ] } ] }, { "uniprot_ac": "A0A8V1AMQ2", "gene_name": "CAMKK1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AMQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMQ2" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V1AMQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMQ2" } ] } ] }, { "uniprot_ac": "A0A8V1AP60", "gene_name": "KSR1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AP60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP60" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AP60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP60" } ] } ] }, { "uniprot_ac": "E1BQN6", "gene_name": "PRKCZ", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BQN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQN6" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1BQN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQN6" } ] } ] }, { "uniprot_ac": "E1BQV7", "gene_name": "SLK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BQV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQV7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BQV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQV7" } ] } ] }, { "uniprot_ac": "E1BUG0", "gene_name": "CDK12", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] } ] }, { "uniprot_ac": "E1BW33", "gene_name": "SMG1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BW33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BW33" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BW33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BW33" } ] } ] }, { "uniprot_ac": "E1BWA3", "gene_name": "PRKCI", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BWA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWA3" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1BWA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWA3" } ] } ] }, { "uniprot_ac": "E1BWT0", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BWT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWT0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BWT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWT0" } ] } ] }, { "uniprot_ac": "E1BX69", "gene_name": "EIF2AK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BX69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BX69" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BX69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BX69" } ] } ] }, { "uniprot_ac": "E1BY69", "gene_name": "PIM3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BY69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BY69" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BY69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BY69" } ] } ] }, { "uniprot_ac": "E1BYH2", "gene_name": "TAOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BYH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BYH2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BYH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BYH2" } ] } ] }, { "uniprot_ac": "E1C093", "gene_name": "PIK3CG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.154", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.154", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] } ] }, { "uniprot_ac": "E1C2I2", "gene_name": "MASTL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C2I2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C2I2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C2I2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C2I2" } ] } ] }, { "uniprot_ac": "E1C581", "gene_name": "TBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C581", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C581" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C581", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C581" } ] } ] }, { "uniprot_ac": "E1C6T4", "gene_name": "PRKD3", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C6T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C6T4" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1C6T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C6T4" } ] } ] }, { "uniprot_ac": "E1C764", "gene_name": "BMP2K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C764", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C764" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C764", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C764" } ] } ] }, { "uniprot_ac": "E1C848", "gene_name": "MAP3K8", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C848", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C848" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1C848", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C848" } ] } ] }, { "uniprot_ac": "F1NA68", "gene_name": "CDK3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NA68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NA68" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1NA68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NA68" } ] } ] }, { "uniprot_ac": "F1NB57", "gene_name": "PLK2", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NB57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NB57" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "F1NB57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NB57" } ] } ] }, { "uniprot_ac": "F1NBT0", "gene_name": "STK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NBT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NBT0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1NBT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NBT0" } ] } ] }, { "uniprot_ac": "F1NCX7", "gene_name": "PLK1", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NCX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCX7" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "F1NCX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCX7" } ] } ] }, { "uniprot_ac": "F1NCY7", "gene_name": "MAPKAPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NCY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCY7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1NCY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCY7" } ] } ] }, { "uniprot_ac": "F1NJH1", "gene_name": "PRKCH", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NJH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NJH1" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1NJH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NJH1" } ] } ] }, { "uniprot_ac": "F1NKW3", "gene_name": "MAP3K15", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NKW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NKW3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1NKW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NKW3" } ] } ] }, { "uniprot_ac": "F1NLR7", "gene_name": "CLK3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NLR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NLR7" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "F1NLR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NLR7" } ] } ] }, { "uniprot_ac": "F1NUX4", "gene_name": "MTOR", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NUX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NUX4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1NUX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NUX4" } ] } ] }, { "uniprot_ac": "F1NVF2", "gene_name": "MAP2K6", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NVF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NVF2" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "F1NVF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NVF2" } ] } ] }, { "uniprot_ac": "F1P011", "gene_name": "CAMK2A", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1P011", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P011" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "F1P011", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P011" } ] } ] }, { "uniprot_ac": "F1P356", "gene_name": 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O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P05625", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05625" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P05625", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05625" } ] } ] }, { "uniprot_ac": "P10741", "gene_name": "MOS", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P10741", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P10741" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P10741", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P10741" } ] } ] }, { "uniprot_ac": "P13863", "gene_name": "CDK1", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P13863", "database": "UniProtKB", "url": 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O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P79996", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P79996" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "P79996", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P79996" } ] } ] }, { "uniprot_ac": "Q04982", "gene_name": "BRAF", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q04982", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q04982" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q04982", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q04982" } ] } ] }, { "uniprot_ac": "Q0GGW5", "gene_name": "STK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q0GGW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0GGW5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q0GGW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0GGW5" } ] } ] }, { "uniprot_ac": "Q5F3L1", "gene_name": "RPS6KA5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5F3L1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F3L1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q5F3L1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F3L1" } ] } ] }, { "uniprot_ac": "Q5F3W3", "gene_name": "MAPK6", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5F3W3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F3W3" } ] }, { "ec_number": "2.7.11.24", "activity": "", 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"ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q6U1I9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6U1I9" } ] } ] }, { "uniprot_ac": "Q6XUX0", "gene_name": "DSTYK", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q6XUX0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6XUX0" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "Q6XUX0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6XUX0" } ] } ] }, { "uniprot_ac": "Q7T0B1", "gene_name": "STK40", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q7T0B1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q7T0B1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q7T0B1", "database": "UniProtKB", 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"url": "https://www.uniprot.org/uniprotkb/Q9IA88" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9IA88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9IA88" } ] } ] }, { "uniprot_ac": "R4GIN8", "gene_name": "PRKACB", "activity": [ { "ec_number": "2.7.11.11", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "R4GIN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GIN8" } ] }, { "ec_number": "2.7.11.11", "activity": "", "evidence": [ { "id": "R4GIN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GIN8" } ] } ] }, { "uniprot_ac": "R4GJB8", "gene_name": "TESK1", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "R4GJB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GJB8" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "R4GJB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GJB8" } ] } ] } ], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1NKW3-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 1234, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1NKW3-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1NKW3" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.7.11.25", "ec_name": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "2.7.11.25", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.25" }, { "id": "2.7.11.25", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.7.11.25" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1045, "end_pos": 1047 }, { "start_pos": 1199, "end_pos": 1201 }, { "start_pos": 447, "end_pos": 449 }, { "start_pos": 803, "end_pos": 805 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1NIC0-1", "uniprot_ac": "F1NIC0", "uniprot_id": "F1NIC0_CHICK", "mass": { "chemical_mass": 103018.0, "monoisotopic_mass": 103018.0 }, "refseq": {}, "gene_names": [ { "name": "UNC5C", "type": "recommended", "evidence": [ { "id": "F1NIC0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NIC0" } ] } ], "protein_names": [ { "name": "Netrin receptor UNC5", "type": "recommended", "evidence": [ { "id": "F1NIC0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NIC0/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": 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"https://www.uniprot.org/uniprotkb/F1NIC0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "UNC5C", "url": "https://www.uniprot.org/uniprotkb/F1NIC0", "locus": { "chromosome": "4", "start_pos": 58117403, "end_pos": 58357037, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010004366", "url": "https://www.ensembl.org/id/ENSGALG00010004366" } ] } } ], "crossref": [ { "id": "F1NIC0", "url": "https://alphafold.ebi.ac.uk/entry/F1NIC0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000012219", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000012219", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd08799", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd08799", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "395101", "url": "https://www.ncbi.nlm.nih.gov/gene/395101", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000488", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000488", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000884", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000884", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000906", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000906", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003598", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003598", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011029", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011029", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013098", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013098", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033772", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033772", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036383", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036383", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037936", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037936", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042154", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042154", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057755", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057755", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:395101", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:395101", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CECQAWS", "url": "https://omabrowser.org/oma/group/CECQAWS/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XCU6", "url": "https://www.orthodb.org/?gene=A0A8V0XCU6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XGX4", "url": "https://www.orthodb.org/?gene=A0A8V0XGX4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XGY3", "url": "https://www.orthodb.org/?gene=A0A8V0XGY3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NIC0", "url": "https://www.orthodb.org/?gene=F1NIC0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NTX3", "url": "https://www.orthodb.org/?gene=F1NTX3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12582", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12582", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12582:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12582:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00090", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00090", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00531", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00531", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00791", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00791", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07679", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07679", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17217", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17217", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25609", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25609", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_989782", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989782", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0XCU6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCU6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XCU6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCU6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XGX4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XGX4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XGX4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XGX4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XGY3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XGY3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XGY3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XGY3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NIC0", "url": "https://www.uniprot.org/uniprotkb/F1NIC0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NIC0-1", "url": "https://www.uniprot.org/uniprotkb/F1NIC0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NTX3", "url": "https://www.uniprot.org/uniprotkb/F1NTX3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NTX3-1", "url": "https://www.uniprot.org/uniprotkb/F1NTX3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGKGLEGTAARCGLGMGYLLHSVVLPALAVLGASRPGSAAQDDDFFHELPETFPSDPPEPLPHFLIEPEEAYIVKNKPVNLYCKASPATQIYFKCNSEWVHQKDHVVDERVDETSGLIVREVSIEISRQQVEELFGPEDYWCQCVAWSSAGTTKSRKAYVRIAYLRKTFEQEPLGKEVSLEQEVLLQCRPPEGIPVAEVEWLKNEEVIDPVEDRNFYITIDHNLIIKQARLSDTANYTCVAKNIVAKRKSTTATVIVYVNGGWSTWTEWSVCNSRCGRGFQKRTRTCTNPAPLNGGAFCEGQNVQKIACTTLCPVDGKWTSWSKWSTCGTECTHWRRRECTAPAPKNGGKDCEGLVLQSKNCTDGLCMQAAPDSDDVALYVGIVIAVIVCLAISVVVALFVYRKNHRDFESDIIDSSALNGGFQPVNIKAARQDLLAVPPDLTSAAAMYRGPVYALHDVSDKIPMTNSPILDPLPNLKIKVYNTSGAVTPQDELSDFSSKLSPQITQSLLENETLNVKNQSLARQTDPSCTAFGTFNSLGGHLVIPNSGVSLLIPAGAVPQGRVYEMYVTVHRKEGMRPPVEDSQTLLTPVVSCGPPGALLTRPVVLTMHHCAEPNMDDWQIQLKHQAAQGPWEDVVVVGEENFTTPCYIQLDPEACHILTETLSTYALVGQSITKAAAKRLKLAIFGPLSCSSLEYSIRVYCLDDTQDALKEVLQLERQMGGQLLEEPKTLHFKGSTHNLRLSIHDIAHSLWKSKLLAKYQEIPFYHIWSGCQRNLHCTFTLERFSLNTLELVCKLCVRQVEGEGQIFQLNCSVSEEPTGIDYPIMDSAGSITTIVGPNAFSIPLPIRQKLCSSLDAPQTRGHDWRMLAHKLKLDRYLNYFATKSSPTGVILDLWEAQNFPDGNLSMLAAVLEEMGRHETVVSLAAEGNY", "length": 931, "header": "tr|F1NIC0-1|F1NIC0_CHICK Isoform 1 of Netrin receptor UNC5 OS=Gallus gallus OX=9031 GN=UNC5C PE=3 SV=1 CANONICAL=F1NIC0-1" }, "isoforms": [ { "isoform_ac": "A0A8V0XCU6-1", "url": "https://www.uniprot.org/uniprotkb/F1NIC0/entry#A0A8V0XCU6-1", "sequence": { "sequence": "MTKASNSDDDFFHELPETFPSDPPEPLPHFLIEPEEAYIVKNKPVNLYCKASPATQIYFKCNSEWVHQKDHVVDERVDETSGLIVREVSIEISRQQVEELFGPEDYWCQCVAWSSAGTTKSRKAYVRIAYLRKTFEQEPLGKEVSLEQEVLLQCRPPEGIPVAEVEWLKNEEVIDPVEDRNFYITIDHNLIIKQARLSDTANYTCVAKNIVAKRKSTTATVIVYVNGGWSTWTEWSVCNSRCGRGFQKRTRTCTNPAPLNGGAFCEGQNVQKIACTTLCPVDGKWTSWSKWSTCGTECTHWRRRECTAPAPKNGGKDCEGLVLQSKNCTDGLCMQGFIYPISTEQRTQNEYGFSSAPDSDDVALYVGIVIAVIVCLAISVVVALFVYRKNHRDFESDIIDSSALNGGFQPVNIKAARQDLLAVPPDLTSAAAMYRGPVYALHDVSDKIPMTNSPILDPLPNLKIKVYNTSGAVTPQDELSDFSSKLSPQITQSLLENETLNVKNQSLARQTDPSCTAFGTFNSLGGHLVIPNSGVSLLIPAGAVPQGRVYEMYVTVHRKEGMRPPVEDSQTLLTPVVSCGPPGALLTRPVVLTMHHCAEPNMDDWQIQLKHQAAQGPWEDVVVVGEENFTTPCYIQLDPEACHILTETLSTYALVGQSITKAAAKRLKLAIFGPLSCSSLEYSIRVYCLDDTQDALKEVLQLERQMGGQLLEEPKTLHFKGSTHNLRLSIHDIAHSLWKSKLLAKYQEIPFYHIWSGCQRNLHCTFTLERFSLNTLELVCKLCVRQVEGEGQIFQLNCSVSEEPTGIDYPIMDSAGSITTIVGPNAFSIPLPIRQKLCSSLDAPQTRGHDWRMLAHKLKLDRYLNYFATKSSPTGVILDLWEAQNFPDGNLSMLAAVLEEMGRHETVVSLAAEGNY", "length": 916, "header": "tr|A0A8V0XCU6-1|F1NIC0_CHICK Computationally mapped isoform of Netrin receptor UNC5 OS=Gallus gallus OX=9031 GN=UNC5C PE=3 SV=1 CANONICAL=F1NIC0-1" }, "locus": { "chromosome": "4", "start_pos": 58253906, "end_pos": 58118239, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010010193.1", "url": "https://www.ensembl.org/id/ENSGALT00010010193.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010005955.1", "url": "https://www.ensembl.org/id/ENSGALP00010005955.1" } ] } }, { "isoform_ac": "A0A8V0XGX4-1", "url": "https://www.uniprot.org/uniprotkb/F1NIC0/entry#A0A8V0XGX4-1", "sequence": { "sequence": "MGTIRSRLKPVIEHLVKGHSQPWEHRCEQFTCLTGRGAPRVQPSLTHLRAGSQRRRIFTWRLPSLGVSSKPCSSKRNDDFFHELPETFPSDPPEPLPHFLIEPEEAYIVKNKPVNLYCKASPATQIYFKCNSEWVHQKDHVVDERVDETSGLIVREVSIEISRQQVEELFGPEDYWCQCVAWSSAGTTKSRKAYVRIAYLRKTFEQEPLGKEVSLEQEVLLQCRPPEGIPVAEVEWLKNEEVIDPVEDRNFYITIDHNLIIKQARLSDTANYTCVAKNIVAKRKSTTATVIVYVNGGWSTWTEWSVCNSRCGRGFQKRTRTCTNPAPLNGGAFCEGQNVQKIACTTLCPVDGKWTSWSKWSTCGTECTHWRRRECTAPAPKNGGKDCEGLVLQSKNCTDGLCMQGFIYPISTEQRTQNEYGFSSAPDSDDVALYVGIVIAVIVCLAISVVVALFVYRKNHRDFESDIIDSSALNGGFQPVNIKAARQDLLAVPPDLTSAAAMYRGPVYALHDVSDKIPMTNSPILDPLPNLKIKVYNTSGAVTPQDELSDFSSKLSPQITQSLLENETLNVKNQSLARQTDPSCTAFGTFNSLGGHLVIPNSGVSLLIPAGAVPQGRVYEMYVTVHRKEGMRPPVEDSQTLLTPVVSCGPPGALLTRPVVLTMHHCAEPNMDDWQIQLKHQAAQGPWEDVVVVGEENFTTPCYIQLDPEACHILTETLSTYALVGQSITKAAAKRLKLAIFGPLSCSSLEYSIRVYCLDDTQDALKEVLQLERQMGGQLLEEPKTLHFKGSTHNLRLSIHDIAHSLWKSKLLAKYQEIPFYHIWSGCQRNLHCTFTLERFSLNTLELVCKLCVRQVEGEGQIFQLNCSVSEEPTGIDYPIMDSAGSITTIVGPNAFSIPLPIRQKLCSSLDAPQTRGHDWRMLAHKLKLDRYLNYFATKSSPTGVILDLWEAQNFPDGNLSMLAAVLEEMGRHETVVSLAAEGNY", "length": 985, "header": "tr|A0A8V0XGX4-1|F1NIC0_CHICK Computationally mapped isoform of Netrin receptor UNC5 OS=Gallus gallus OX=9031 GN=UNC5C PE=3 SV=1 CANONICAL=F1NIC0-1" }, "locus": { "chromosome": "4", "start_pos": 58336669, "end_pos": 58118239, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010010197.1", "url": "https://www.ensembl.org/id/ENSGALT00010010197.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010005959.1", "url": "https://www.ensembl.org/id/ENSGALP00010005959.1" } ] } }, { "isoform_ac": "A0A8V0XGY3-1", "url": "https://www.uniprot.org/uniprotkb/F1NIC0/entry#A0A8V0XGY3-1", "sequence": { "sequence": "MGKGLEGTAARCGLGMGYLLHSVVLPALAVLGASRPGSAAQDDDFFHELPETFPSDPPEPLPHFLIEPEEAYIVKNKPVNLYCKASPATQIYFKCNSEWVHQKDHVVDERVDETSGLIVREVSIEISRQQVEELFGPEDYWCQCVAWSSAGTTKSRKAYVRIAYLRKTFEQEPLGKEVSLEQEVLLQCRPPEGIPVAEVEWLKNEEVIDPVEDRNFYITIDHNLIIKQARLSDTANYTCVAKNIVAKRKSTTATVIVYVNGGWSTWTEWSVCNSRCGRGFQKRTRTCTNPAPLNGGAFCEGQNVQKIACTTLCPVDGKWTSWSKWSTCGTECTHWRRRECTAPAPKNGGKDCEGLVLQSKNCTDGLCMQDLLAVPPDLTSAAAMYRGPVYALHDVSDKIPMTNSPILDPLPNLKIKVYNTSGAVTPQDELSDFSSKLSPQITQSLLENETLNVKNQSLARQTDPSCTAFGTFNSLGGHLVIPNSGVSLLIPAGAVPQGRVYEMYVTVHRKEGMRPPVEDSQTLLTPVVSCGPPGALLTRPVVLTMHHCAEPNMDDWQIQLKHQAAQGPWEDVVVVGEENFTTPCYIQLDPEACHILTETLSTYALVGQSITKAAAKRLKLAIFGPLSCSSLEYSIRVYCLDDTQDALKEVLQLERQMGGQLLEEPKTLHFKGSTHNLRLSIHDIAHSLWKSKLLAKYQEIPFYHIWSGCQRNLHCTFTLERFSLNTLELVCKLCVRQVEGEGQIFQLNCSVSEEPTGIDYPIMDSAGSITTIVGPNAFSIPLPIRQKLCSSLDAPQTRGHDWRMLAHKLKLDRYLNYFATKSSPTGVILDLWEAQNFPDGNLSMLAAVLEEMGRHETVVSLAAEGNY", "length": 867, "header": "tr|A0A8V0XGY3-1|F1NIC0_CHICK Computationally mapped isoform of Netrin receptor UNC5 OS=Gallus gallus OX=9031 GN=UNC5C PE=3 SV=1 CANONICAL=F1NIC0-1" }, "locus": { "chromosome": "4", "start_pos": 58356924, "end_pos": 58118239, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010010210.1", "url": "https://www.ensembl.org/id/ENSGALT00010010210.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010005969.1", "url": "https://www.ensembl.org/id/ENSGALP00010005969.1" } ] } }, { "isoform_ac": "F1NIC0-1", "url": "https://www.uniprot.org/uniprotkb/F1NIC0/entry#F1NIC0-1", "sequence": { "sequence": "MGKGLEGTAARCGLGMGYLLHSVVLPALAVLGASRPGSAAQDDDFFHELPETFPSDPPEPLPHFLIEPEEAYIVKNKPVNLYCKASPATQIYFKCNSEWVHQKDHVVDERVDETSGLIVREVSIEISRQQVEELFGPEDYWCQCVAWSSAGTTKSRKAYVRIAYLRKTFEQEPLGKEVSLEQEVLLQCRPPEGIPVAEVEWLKNEEVIDPVEDRNFYITIDHNLIIKQARLSDTANYTCVAKNIVAKRKSTTATVIVYVNGGWSTWTEWSVCNSRCGRGFQKRTRTCTNPAPLNGGAFCEGQNVQKIACTTLCPVDGKWTSWSKWSTCGTECTHWRRRECTAPAPKNGGKDCEGLVLQSKNCTDGLCMQAAPDSDDVALYVGIVIAVIVCLAISVVVALFVYRKNHRDFESDIIDSSALNGGFQPVNIKAARQDLLAVPPDLTSAAAMYRGPVYALHDVSDKIPMTNSPILDPLPNLKIKVYNTSGAVTPQDELSDFSSKLSPQITQSLLENETLNVKNQSLARQTDPSCTAFGTFNSLGGHLVIPNSGVSLLIPAGAVPQGRVYEMYVTVHRKEGMRPPVEDSQTLLTPVVSCGPPGALLTRPVVLTMHHCAEPNMDDWQIQLKHQAAQGPWEDVVVVGEENFTTPCYIQLDPEACHILTETLSTYALVGQSITKAAAKRLKLAIFGPLSCSSLEYSIRVYCLDDTQDALKEVLQLERQMGGQLLEEPKTLHFKGSTHNLRLSIHDIAHSLWKSKLLAKYQEIPFYHIWSGCQRNLHCTFTLERFSLNTLELVCKLCVRQVEGEGQIFQLNCSVSEEPTGIDYPIMDSAGSITTIVGPNAFSIPLPIRQKLCSSLDAPQTRGHDWRMLAHKLKLDRYLNYFATKSSPTGVILDLWEAQNFPDGNLSMLAAVLEEMGRHETVVSLAAEGNY", "length": 931, "header": "tr|F1NIC0-1|F1NIC0_CHICK Isoform 1 of Netrin receptor UNC5 OS=Gallus gallus OX=9031 GN=UNC5C PE=3 SV=1 CANONICAL=F1NIC0-1" }, "locus": { "chromosome": "4", "start_pos": 58356924, "end_pos": 58118239, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010010205.1", "url": "https://www.ensembl.org/id/ENSGALT00010010205.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010005966.1", "url": "https://www.ensembl.org/id/ENSGALP00010005966.1" } ] } }, { "isoform_ac": "F1NTX3-1", "url": "https://www.uniprot.org/uniprotkb/F1NIC0/entry#F1NTX3-1", "sequence": { "sequence": "MGKGLEGTAARCGLGMGYLLHSVVLPALAVLGASRPGSAAQDDDFFHELPETFPSDPPEPLPHFLIEPEEAYIVKNKPVNLYCKASPATQIYFKCNSEWVHQKDHVVDERVDETSGLIVREVSIEISRQQVEELFGPEDYWCQCVAWSSAGTTKSRKAYVRIAYLRKTFEQEPLGKEVSLEQEVLLQCRPPEGIPVAEVEWLKNEEVIDPVEDRNFYITIDHNLIIKQARLSDTANYTCVAKNIVAKRKSTTATVIVYVNGGWSTWTEWSVCNSRCGRGFQKRTRTCTNPAPLNGGAFCEGQNVQKIACTTLCPVDGKWTSWSKWSTCGTECTHWRRRECTAPAPKNGGKDCEGLVLQSKNCTDGLCMQGFIYPISTEQRTQNEYGFSSAPDSDDVALYVGIVIAVIVCLAISVVVALFVYRKNHRDFESDIIDSSALNGGFQPVNIKAARQDLLAVPPDLTSAAAMYRGPVYALHDVSDKIPMTNSPILDPLPNLKIKVYNTSGAVTPQDELSDFSSKLSPQITQSLLENETLNVKNQSLARQTDPSCTAFGTFNSLGGHLVIPNSGVSLLIPAGAVPQGRVYEMYVTVHRKEGMRPPVEDSQTLLTPVVSCGPPGALLTRPVVLTMHHCAEPNMDDWQIQLKHQAAQGPWEDVVVVGEENFTTPCYIQLDPEACHILTETLSTYALVGQSITKAAAKRLKLAIFGPLSCSSLEYSIRVYCLDDTQDALKEVLQLERQMGGQLLEEPKTLHFKGSTHNLRLSIHDIAHSLWKSKLLAKYQEIPFYHIWSGCQRNLHCTFTLERFSLNTLELVCKLCVRQVEGEGQIFQLNCSVSEEPTGIDYPIMDSAGSITTIVGPNAFSIPLPIRQKLCSSLDAPQTRGHDWRMLAHKLKLDRYLNYFATKSSPTGVILDLWEAQNFPDGNLSMLAAVLEEMGRHETVVSLAAEGNY", "length": 950, "header": "tr|F1NTX3-1|F1NTX3_CHICK Computationally mapped isoform of Netrin receptor UNC5 OS=Gallus gallus OX=9031 GN=UNC5C PE=3 SV=4 CANONICAL=F1NIC0-1" }, "locus": { "chromosome": "4", "start_pos": 58356924, "end_pos": 58118239, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010010215.1", "url": "https://www.ensembl.org/id/ENSGALT00010010215.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010005973.1", "url": "https://www.ensembl.org/id/ENSGALP00010005973.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:395101", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:395101", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0R4IEH4-1", "protein_name": "Netrin receptor UNC5", "gene_name": "unc5da", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MMGRFGKKGRYSCFGFLAVLILLLPYAMARGSRDGQSAMSGTLPHFLQEPDDAYIVKSNPIKLRCRARPALQIFFKCNGEWVHQNQHTSLEHIELGTGLKIREVMINVSRQQVEDFHGPEDYWCLCVAWSHLGTAKSRKATVRIAYLRKNFEQEPQGMEVPINGMIVLHCRPPEGVPAAEVEWLKNEELVHSLEDINIDTRADHNLIINEARLSDSGNYTCLASNIVARRRSATAMVIVFVNGGWSSWTDWSECNVRCGRGVQKRTRTCTNPAPLNGGAFCEGMSVQKSTCTSPCPVDGGWSEWTMWSECTSECERQRTRECTDPEPKHGGRLCDGAALDTDNCTGDLCIQDRKLLHDVKVPQADVESSNDVALYSGLAAGVVTMVVLVIAVTLYRRNQSEYGVDVIDSSALTGGFQSFSFKSARQGNPLLMNSSMQPDLTVSRTYTSPICFPDSMEKELIPEPALFDPLPDLKVKVHSSFMVSLGVSERAEYHAKAPSQTFPRGVVQEIGGGGGTLGGRGKSQLTSIQPALISSMTNGKRALRTSGVFGHGGGRLVVPNAGVSLLVPHGAIEEDTTWELYMSITQQDSSALSDEAQEILLSPEVTYGPPGLSLSCPVALTVAHCADVNSEDWNIKLKRQTQDNSWEEVMILEEESTSCYCLLDTQCCHLLVERPGCYALVGEALSQAAGKRLRLAAFGNMEPNFLNYSIRVYCVDDTPHAFQEVVSVERGRGGRLLEEPKTLLFRANSFSLQVSIQDIPQFLWSIKPFTTCQEFSFSQVWCSSQSPLQCAFSLERYSPAANQLSCKISVRQVKGHEQILQVYTTIAESEKDTVPFFTQSDCTITSQTGSRAFKIPQSIRQRICATFDTANAKGKDWQLLAQKLHIDRNLGYFARQTSPSAVILSLWEAQHQEQGDLDSLASALEEIGKVQSKQSTSADTLDRISKTIPSSDSTLNRSSEELDANHT", "length": 967 }, "evidence": [ { "id": "F1NIC0", "url": "https://omabrowser.org/oma/group/F1NIC0/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8C2N1Q7-1", "protein_name": "Netrin receptor UNC5", "gene_name": "Unc5c", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MRKGLRATAARCGLGLGYLLQMLVLPALALLSASGTGSAAQDDDFFHELPETFPSDPPEPLPHFLIEPEEAYIVKNKPVNLYCKASPATQIYFKCNSEWVHQKDHVVDERVDETSGLIVREVSIEISRQQVEELFGPEDYWCQCVAWSSAGTTKSRKAYVRIAYLRKTFEQEPLGKEVSLEQEVLLQCRPPEGIPVAEVEWLKNEDIIDPVEDRNFYITIDHNLIIKQARLSDTANYTCVAKNIVAKRKSTTATVIVYVNGGWSTWTEWSVCNSRCGRGYQKRTRTCTNPAPLNGGAFCEGQSVQKIACTTLCPVDGRWTSWSKWSPCGTECTHWRRRECTAPAPKNGGKDCDGLVLQSKNCTDGLCMQGFIYPIPTDHRTQNEYGFSSAPDSDDVALYVGIVIAVTVCLAITIVVALFVYRKNHRDFESDIIDSSALNGGFQPVNIKAARQDLLAVPPDLTSAAAMYRGPVYALHDVSDKIPMTNSPILDPLPNLKIKVYNTSGAVTPQDDLSEFTSKLSPQMTQSLLENEALNMKNQSLARQTDPSCTAFGTFNSLGGHLIIPNSGVSLLIPAGAIPQGRVYEMYVTVHRKENMRPPMEDSQTLLTPVVSCGPSGALLTRPVILTLHHCADPNTEDWKIQLKNQAVQGQWEDVVVVGEENFTTPCYIQLDAEACHILTENLSTYALVGQSTTKAAAKRLKLAIFGPLCCSSLEYSIRVYCLDDTQDALKEVLQLERQMGGQLLEEPKALHFKGSIHNLRLSIHDIAHSLWKSKLLAKYQEIPFYHIWSGSQRNLHCTFTLERLSLNTVELVCKLCVRQVEGEGQIFQLNCTVSEEPTGIDLPLLDPASTITTVTGPSAFSIPLPIRQKLCSSLDAPQTRGHDWRMLAHKLNLDRYLNYFATKSSPTGVILDLWEAQNFPDGNLSMLAAVLEEMGRHETVMSLAAEGQY", "length": 950 }, "evidence": [ { "id": "F1NIC0", "url": "https://omabrowser.org/oma/group/F1NIC0/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "O08747-1", "protein_name": "Netrin receptor UNC5C", "gene_name": "Unc5c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRKGLRATAARCGLGLGYLLQMLVLPALALLSASGTGSAAQDDEFFHELPETFPSDPPEPLPHFLIEPEEAYIVKNKPVNLYCKASPATQIYFKCNSEWVHQKDHVVDERVDETSGLIVREVSIEISRQQVEELFGPEDYWCQCVAWSSAGTTKSRKAYVRIAYLRKTFEQEPLGKEVSLEQEVLLQCRPPEGIPVAEVEWLKNEDIIDPAEDRNFYITIDHNLIIKQARLSDTANYTCVAKNIVAKRKSTTATVIVYVNGGWSTWTEWSVCNSRCGRGYQKRTRTCTNPAPLNGGAFCEGQSVQKIACTTLCPVDGRWTSWSKWSTCGTECTHWRRRECTAPAPKNGGKDCDGLVLQSKNCTDGLCMQAAPDSDDVALYVGIVIAVTVCLAITVVVALFVYRKNHRDFESDIIDSSALNGGFQPVNIKAARQDLLAVPPDLTSAAAMYRGPVYALHDVSDKIPMTNSPILDPLPNLKIKVYNSSGAVTPQDDLAEFSSKLSPQMTQSLLENEALNLKNQSLARQTDPSCTAFGTFNSLGGHLIIPNSGVSLLIPAGAIPQGRVYEMYVTVHRKENMRPPMEDSQTLLTPVVSCGPPGALLTRPVILTLHHCADPSTEDWKIQLKNQAVQGQWEDVVVVGEENFTTPCYIQLDAEACHILTENLSTYALVGQSTTKAAAKRLKLAIFGPLCCSSLEYSIRVYCLDDTQDALKEVLQLERQMGGQLLEEPKALHFKGSIHNLRLSIHDIAHSLWKSKLLAKYQEIPFYHIWSGSQRNLHCTFTLERLSLNTVELVCKLCVRQVEGEGQIFQLNCTVSEEPTGIDLPLLDPASTITTVTGPSAFSIPLPIRQKLCSSLDAPQTRGHDWRMLAHKLNLDRYLNYFATKSSPTGVILDLWEAQNFPDGNLSMLAAVLEEMGRHETVVSLAAEGQY", "length": 931 }, "evidence": [ { "id": "F1NIC0", "url": "https://omabrowser.org/oma/group/F1NIC0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "O95185-1", "protein_name": "Netrin receptor UNC5C", "gene_name": "UNC5C", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRKGLRATAARCGLGLGYLLQMLVLPALALLSASGTGSAAQDDDFFHELPETFPSDPPEPLPHFLIEPEEAYIVKNKPVNLYCKASPATQIYFKCNSEWVHQKDHIVDERVDETSGLIVREVSIEISRQQVEELFGPEDYWCQCVAWSSAGTTKSRKAYVRIAYLRKTFEQEPLGKEVSLEQEVLLQCRPPEGIPVAEVEWLKNEDIIDPVEDRNFYITIDHNLIIKQARLSDTANYTCVAKNIVAKRKSTTATVIVYVNGGWSTWTEWSVCNSRCGRGYQKRTRTCTNPAPLNGGAFCEGQSVQKIACTTLCPVDGRWTPWSKWSTCGTECTHWRRRECTAPAPKNGGKDCDGLVLQSKNCTDGLCMQTAPDSDDVALYVGIVIAVIVCLAISVVVALFVYRKNHRDFESDIIDSSALNGGFQPVNIKAARQDLLAVPPDLTSAAAMYRGPVYALHDVSDKIPMTNSPILDPLPNLKIKVYNTSGAVTPQDDLSEFTSKLSPQMTQSLLENEALSLKNQSLARQTDPSCTAFGSFNSLGGHLIVPNSGVSLLIPAGAIPQGRVYEMYVTVHRKETMRPPMDDSQTLLTPVVSCGPPGALLTRPVVLTMHHCADPNTEDWKILLKNQAAQGQWEDVVVVGEENFTTPCYIQLDAEACHILTENLSTYALVGHSTTKAAAKRLKLAIFGPLCCSSLEYSIRVYCLDDTQDALKEILHLERQMGGQLLEEPKALHFKGSTHNLRLSIHDIAHSLWKSKLLAKYQEIPFYHVWSGSQRNLHCTFTLERFSLNTVELVCKLCVRQVEGEGQIFQLNCTVSEEPTGIDLPLLDPANTITTVTGPSAFSIPLPIRQKLCSSLDAPQTRGHDWRMLAHKLNLDRYLNYFATKSSPTGVILDLWEAQNFPDGNLSMLAAVLEEMGRHETVVSLAAEGQY", "length": 931 }, "evidence": [ { "id": "F1NIC0", "url": "https://omabrowser.org/oma/group/F1NIC0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q761X5-1", "protein_name": "Netrin receptor UNC5C", "gene_name": "Unc5c", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRKGLRATAARCGLGLGYLLQMLVLPALALLSASGTGSAAQDDDFFHELPETFPSDPPEPLPHFLIEPEEAYIVKNKPVNLYCKASPATQIYFKCNSEWVHQKDHVVDERVDETSGLIVREVSIEISRQQVEELFGPEDYWCQCVAWSSAGTTKSRKAYVRIAYLRKTFEQEPLGKEVSLEQEVLLQCRPPEGIPMAEVEWLKNEDIIDPVEDRNFYITIDHNLIIKQARLSDTANYTCVAKNIVAKRKSTTATVIVYVNGGWSTWAEWSVCNSRCGRGYQKRTRTCTNPAPLNGGAFCEGQSVQKIACTTLCPVDGRWTSWSKWSTCGTECTHWRRRECTAPAPKNGGKDCDGLVLQSKNCTDGLCMQAAPDSDDVALYVGIVIAVTVCLAITVVVALFVYRKNHRDFESNIIDSSALNGGFQPVNIKAARQDLLAVPPDLTSAAAMYRGPVYALHDVSDKIPMTNSPILDPLPNLKIKVYNSSGAVTPQDDLAEFSSKLSPQMTQSLLENEALNLKNQSLARQTDPSCTAFGTFNSLGGHLIIPNSGVSLLIPAGAIPQGRVYEMYVTVHRKENMRPPMEDSQTLLTPVVSCGPPGALLTRPVILTLHHCADPNTEDWKIQLKNQAVQGQWEDVVVVGEENFTTPCYIQLDAEACHILTENLSTYALVGQSTTKAAAKRLKLAIFGPLCCSSLEYSIRVYCLDDTQDALKEVLQLERQMGGQLLEEPKALHFKGSIHNLRLSIHDITHSLWKSKLLAKYQEIPFYHIWSGSQRNLHCTFTLERLSLNTVELVCKLCVRQVEGEGQIFQLNCTVSEEPTGIDLPLLDPASTITTVTGPSAFSIPLPIRQKLCSSLDAPQTRGHDWRMLAHKLNLDRYLNYFATKSSPTGVILDLWEAQNFPDGNLSMLAAVLEEMGRHETVVSLAAEGQY", "length": 931 }, "evidence": [ { "id": "F1NIC0", "url": "https://omabrowser.org/oma/group/F1NIC0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F1NIC0", "url": "https://www.uniprot.org/uniprotkb/F1NIC0" } ], "pmid": "" }, { "name": "lamellipodium", "id": "GO:0030027", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030027", "evidence": [ { "database": "UniProtKB", "id": "F1NIC0", "url": "https://www.uniprot.org/uniprotkb/F1NIC0" } ], "pmid": "" }, { "name": "dendrite", "id": "GO:0030425", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030425", "evidence": [ { "database": "UniProtKB", "id": "F1NIC0", "url": "https://www.uniprot.org/uniprotkb/F1NIC0" } ], "pmid": "" }, { "name": "growth cone", "id": "GO:0030426", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030426", "evidence": [ { "database": "UniProtKB", "id": "F1NIC0", "url": "https://www.uniprot.org/uniprotkb/F1NIC0" } ], "pmid": "" }, { "name": "neuronal cell body", "id": "GO:0043025", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043025", "evidence": [ { "database": "UniProtKB", "id": "F1NIC0", "url": "https://www.uniprot.org/uniprotkb/F1NIC0" } ], "pmid": "" }, { "name": "filopodium", "id": "GO:0030175", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030175", "evidence": [ { "database": "UniProtKB", "id": "F1NIC0", "url": "https://www.uniprot.org/uniprotkb/F1NIC0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "netrin receptor activity", "id": "GO:0005042", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005042", "evidence": [ { "database": "UniProtKB", "id": "F1NIC0", "url": "https://www.uniprot.org/uniprotkb/F1NIC0" } ], "pmid": "" }, { "name": "protein kinase binding", "id": "GO:0019901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019901", "evidence": [ { "database": "UniProtKB", "id": "F1NIC0", "url": "https://www.uniprot.org/uniprotkb/F1NIC0" } ], "pmid": "" }, { "name": "tubulin binding", "id": "GO:0015631", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015631", "evidence": [ { "database": "UniProtKB", "id": "F1NIC0", "url": "https://www.uniprot.org/uniprotkb/F1NIC0" } ], "pmid": "" }, { "name": "netrin receptor activity involved in chemorepulsion", "id": "GO:0005043", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005043", "evidence": [ { "database": "UniProtKB", "id": "F1NIC0", "url": "https://www.uniprot.org/uniprotkb/F1NIC0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "axon guidance", "id": "GO:0007411", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007411", "evidence": [ { "database": "UniProtKB", "id": "F1NIC0", "url": "https://www.uniprot.org/uniprotkb/F1NIC0" } ], "pmid": "" }, { "name": "chemorepulsion of axon", "id": "GO:0061643", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061643", "evidence": [ { "database": "UniProtKB", "id": "F1NIC0", "url": "https://www.uniprot.org/uniprotkb/F1NIC0" } ], "pmid": "" }, { "name": "dorsal root ganglion development", "id": "GO:1990791", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990791", "evidence": [ { "database": "UniProtKB", "id": "F1NIC0", "url": "https://www.uniprot.org/uniprotkb/F1NIC0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 236, "end_pos": 238, "annotation": "n_glycosylation_sequon" }, { "start_pos": 361, "end_pos": 363, "annotation": "n_glycosylation_sequon" }, { "start_pos": 483, "end_pos": 485, "annotation": "n_glycosylation_sequon" }, { "start_pos": 512, "end_pos": 514, "annotation": "n_glycosylation_sequon" }, { "start_pos": 519, "end_pos": 521, "annotation": "n_glycosylation_sequon" }, { "start_pos": 643, "end_pos": 645, "annotation": "n_glycosylation_sequon" }, { "start_pos": 812, "end_pos": 814, "annotation": "n_glycosylation_sequon" }, { "start_pos": 905, "end_pos": 907, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 236, "end_pos": 238 }, { "start_pos": 361, "end_pos": 363 }, { "start_pos": 483, "end_pos": 485 }, { "start_pos": 512, "end_pos": 514 }, { "start_pos": 519, "end_pos": 521 }, { "start_pos": 643, "end_pos": 645 }, { "start_pos": 812, "end_pos": 814 }, { "start_pos": 905, "end_pos": 907 } ] }, "class_list": [], 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"N4-(N-acetyl-beta-glucosaminyl)-L-asparagine amidase", "type": "synonym", "evidence": [ { "id": "F1NQI0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NQI0/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ720474.1, HAEK01008268.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000073.1. On Dec 8, 2021 this sequence version replaced NP_001006445.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001006445", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006445" } ] }, { "annotation": "Cleaves the GlcNAc-Asn bond which joins oligosaccharides to the peptide of asparagine-linked glycoproteins.", "evidence": [ { "database": "UniProtKB", "id": "F1NQI0", "url": "https://www.uniprot.org/uniprotkb/F1NQI0#function" }, { "database": "UniProtKB", "id": "ARBA00053295", "url": "https://www.uniprot.org/uniprotkb/ARBA00053295#function" }, { "database": "UniProtKB", "id": "A0A8V0XD63", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XD63#function" }, { "database": "UniProtKB", "id": "A0A8V0XD67", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XD67#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NQI0", "url": "https://www.uniprot.org/uniprotkb/F1NQI0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "AGA", "url": "https://www.uniprot.org/uniprotkb/F1NQI0", "locus": { "chromosome": "4", "start_pos": 41806802, "end_pos": 41791907, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010004457", "url": "https://www.ensembl.org/id/ENSGALG00010004457" } ] } } ], "crossref": [ { "id": "F1NQI0", "url": "https://alphafold.ebi.ac.uk/entry/F1NQI0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000010716", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000010716", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd04513", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04513", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "422558", "url": "https://www.ncbi.nlm.nih.gov/gene/422558", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000246", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000246", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029055", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029055", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:422558", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422558", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YKPIINI", "url": "https://omabrowser.org/oma/group/YKPIINI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XD63", "url": "https://www.orthodb.org/?gene=A0A8V0XD63", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XD67", "url": "https://www.orthodb.org/?gene=A0A8V0XD67", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NQI0", "url": "https://www.orthodb.org/?gene=F1NQI0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10188", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10188", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10188:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10188:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01112", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01112", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-6798695", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6798695", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001006445", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006445", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "11544", "url": "https://www.rhea-db.org/rhea/11544", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0XD63", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XD63", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XD63-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XD63-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XD67", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XD67", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XD67-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XD67-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NQI0", "url": "https://www.uniprot.org/uniprotkb/F1NQI0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NQI0-1", "url": "https://www.uniprot.org/uniprotkb/F1NQI0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAVAGCASLLLIALQLAGPCGAAATALPVVINTWAFRKATETAWRTLQLGGSELDAVEKGCGQCEIDQCDGSVGYGGSPDESGETTLDAMIMDGNTMEVGAVADLRHVKNAIGVARKVIEHTKHTLLVGESASLFAVRMGFPYEDLTTQRSLSMYSRWLNQSCQPNYWKNVVPDSSKSCGPYKRLEKVSFEEETISQRNVHNHDTIGMVVIGKSGTVASGTSTNGGVHKIPGRVGDSPIAGAGSYADSTAGGAAATGDGDTMMRFLPSYQAVEYMRMGTDPTVACQKVISRIQKHVPKFFGAVICANTTGSYGAACNKIPGFTQFHFMVFSPLQSQPVEQVVDCI", "length": 345, "header": "tr|F1NQI0-1|F1NQI0_CHICK Isoform 1 of N(4)-(Beta-N-acetylglucosaminyl)-L-asparaginase OS=Gallus gallus OX=9031 GN=AGA PE=1 SV=1 CANONICAL=F1NQI0-1" }, "isoforms": [ { "isoform_ac": "A0A8V0XD63-1", "url": "https://www.uniprot.org/uniprotkb/F1NQI0/entry#A0A8V0XD63-1", "sequence": { "sequence": "MAVAGCASLLLIALQLAGPCGAAATALPVVINTWAFRKATETAWRTLQLGGSELDAVEKGCGQCEIDQCDGSVGYGGSPDESGETTLDAMIMDGNTMEVGAVADLRHVKNAIGVARKVIEHTKHTLLVGESASLFAVRMGFPYEDLTTQRSLSMYSRWLNQSCQPNYWKNVVPDSSKSCGPYKRLEKVSFEEETISQRNVHNHDTIGMVVIGKSGTVASGTSTNGGVHKIPGRVGDSPIAGAGSYADSTAGGAAATGDGDTMMRFLPSYQAVEYMRMGTDPTVACQKVISRIQKHVPKFFGAVICANTTGSYGMYLAQQTNFADPD", "length": 326, "header": "tr|A0A8V0XD63-1|F1NQI0_CHICK Computationally mapped isoform of N(4)-(Beta-N-acetylglucosaminyl)-L-asparaginase OS=Gallus gallus OX=9031 GN=AGA PE=1 SV=1 CANONICAL=F1NQI0-1" }, "locus": { "chromosome": "4", "start_pos": 41801549, "end_pos": 41791968, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010010405.1", "url": "https://www.ensembl.org/id/ENSGALT00010010405.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010006071.1", "url": "https://www.ensembl.org/id/ENSGALP00010006071.1" } ] } }, { "isoform_ac": "A0A8V0XD67-1", "url": "https://www.uniprot.org/uniprotkb/F1NQI0/entry#A0A8V0XD67-1", "sequence": { "sequence": "MAVAGCASLLLIALQLAGPCGAAATALPVVINTWAFRKATETAWRTLQLGGSELDAVEKGCGQCEIDQCDGSVGYGGSPDESGETTLDAMIMDGNTMEVGAVADLRHVKNAIGVARKVIEHTKHTLLVGESASLFAVRMGFPYEDLTTQRSLSMYSRWLNQSCQPNYWKNVVPDSSKSCGPYKRLEKVSFEEETISQRNVHNHDTIGMVVIGKSGTVASGTSTNGGVHKIPGRVGDSPIAGAGSYADSTAGGAAATGDGDTMMRFLPSYQAVEYMRMGTDPTVACQKVISRIQKHVPKFFGAVICANTTGSYGRLQITLQLEFHLLPNLTCFDCLCCLKHKKL", "length": 343, "header": "tr|A0A8V0XD67-1|F1NQI0_CHICK Computationally mapped isoform of N(4)-(Beta-N-acetylglucosaminyl)-L-asparaginase OS=Gallus gallus OX=9031 GN=AGA PE=1 SV=1 CANONICAL=F1NQI0-1" }, "locus": { "chromosome": "4", "start_pos": 41805743, "end_pos": 41791968, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010010415.1", "url": "https://www.ensembl.org/id/ENSGALT00010010415.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010006076.1", "url": "https://www.ensembl.org/id/ENSGALP00010006076.1" } ] } }, { "isoform_ac": "F1NQI0-1", "url": "https://www.uniprot.org/uniprotkb/F1NQI0/entry#F1NQI0-1", "sequence": { "sequence": "MAVAGCASLLLIALQLAGPCGAAATALPVVINTWAFRKATETAWRTLQLGGSELDAVEKGCGQCEIDQCDGSVGYGGSPDESGETTLDAMIMDGNTMEVGAVADLRHVKNAIGVARKVIEHTKHTLLVGESASLFAVRMGFPYEDLTTQRSLSMYSRWLNQSCQPNYWKNVVPDSSKSCGPYKRLEKVSFEEETISQRNVHNHDTIGMVVIGKSGTVASGTSTNGGVHKIPGRVGDSPIAGAGSYADSTAGGAAATGDGDTMMRFLPSYQAVEYMRMGTDPTVACQKVISRIQKHVPKFFGAVICANTTGSYGAACNKIPGFTQFHFMVFSPLQSQPVEQVVDCI", "length": 345, "header": "tr|F1NQI0-1|F1NQI0_CHICK Isoform 1 of N(4)-(Beta-N-acetylglucosaminyl)-L-asparaginase OS=Gallus gallus OX=9031 GN=AGA PE=1 SV=1 CANONICAL=F1NQI0-1" }, "locus": { "chromosome": "4", "start_pos": 41802398, "end_pos": 41791968, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010010408.1", "url": "https://www.ensembl.org/id/ENSGALT00010010408.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010006074.1", "url": "https://www.ensembl.org/id/ENSGALP00010006074.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "gga:422558", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422558", "resource": "KEGG Pathway" }, { "id": "R-GGA-6798695", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6798695", "resource": "Reactome", "description": "Neutrophil degranulation" } ], "orthologs": [ { "uniprot_canonical_ac": "F1MGY9-1", "protein_name": "N(4)-(Beta-N-acetylglucosaminyl)-L-asparaginase", "gene_name": "AGA", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAWKPGLLLPLLLLLLGPAPARSFGQLPLVLNTWPFRNATVAAWKTLAAGGSALDAVESGCATCEQQQCDGSVGFGGSPDESGETTLDAMIMDGTTMNVGAVGDLRRIKNAIGVARKVLEHTTHTLLAGEAATKFAESMGFINEDLSTNVSQALHSDWRARNCQPNYWKNVIPDSSKYCGPYKPPTVLKRDGITYEDTAQSYGHDTIGMVVIHKTGNIAAGTSTNGIKFKIPGRIGDSPIPGSGAYADDMVGAAAATGDGDILMRFVPSYQAVEYMRRGENPTTACEKVISRIQKYFPKFFGAVICANVTGSYGAACNKLSTFTQFPFMVYNPLKSAPTEEKVDCI", "length": 346 }, "evidence": [ { "id": "F1NQI0", "url": "https://omabrowser.org/oma/group/F1NQI0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1RT17-1", "protein_name": "N(4)-(Beta-N-acetylglucosaminyl)-L-asparaginase", "gene_name": "AGA", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAQKPILLLMLLLGAAPVRSSSPLPLIVNTWPFRNATQAAWRTLASGGSALDAVESGCAACEREQCDGTVGFGGSPDESGETTLDAMIMDGTTMNVGAVGDLRRIKNAIGVARKVLEHTTHTLLAGEAATKFAESMGFINEDLSTSVSQALHADWLAQNCQPNYWRNVIPDASKYCGPYKPPNILKRDGSTYKETGDSYGHDTIGMVVIHKMGYTAAGTSTNGIKFKIPGRIGDSPIPGSGAYADDTAGAAAATGDGDILMRFLPSYQAVEYMRRGKDPTTACQKVISRIQKYFPNFFGAVICANVTGSYGAACNKLSTFTQFHFMVYNSLKSEPTEEIVDCI", "length": 343 }, "evidence": [ { "id": "F1NQI0", "url": "https://omabrowser.org/oma/group/F1NQI0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3HGM6-1", "protein_name": "N(4)-(Beta-N-acetylglucosaminyl)-L-asparaginase", "gene_name": "Aga", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MARKLSRSLLLLLPFLLGVPLAQGFSPLPLVLNTWPFKNATDAAWRTLVSGGTAVDAVENGCAVCETERCEGTVGFGGSPDEVGETTLDAMIMDGATMNVGAVGDLRRIKNAIGVARRVLDHTTHTLLVGDSATNFAESMGFTVEDLSTTTSKSLHSEWASKNCQPNFWRRVTPDPSKYCGPYKPSGSLEWAISAHKQVDIHNHDTIGMVVIHKTGHVAAGTSTNGLKFKIPGRVGDSPIPGAGAYAEDMIGAAAATGDGDILMRFLPSYQAVEYMRRGDHPTTACQKVIAKIQKYFPKFFGAIICANVMGSYGAACNKHPTFTQFSFMVYNSLRIQPTEEKVDCI", "length": 346 }, "evidence": [ { "id": "F1NQI0", "url": "https://omabrowser.org/oma/group/F1NQI0/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P20933-1", "protein_name": "N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase", "gene_name": "AGA", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MARKSNLPVLLVPFLLCQALVRCSSPLPLVVNTWPFKNATEAAWRALASGGSALDAVESGCAMCEREQCDGSVGFGGSPDELGETTLDAMIMDGTTMDVGAVGDLRRIKNAIGVARKVLEHTTHTLLVGESATTFAQSMGFINEDLSTTASQALHSDWLARNCQPNYWRNVIPDPSKYCGPYKPPGILKQDIPIHKETEDDRGHDTIGMVVIHKTGHIAAGTSTNGIKFKIHGRVGDSPIPGAGAYADDTAGAAAATGNGDILMRFLPSYQAVEYMRRGEDPTIACQKVISRIQKHFPEFFGAVICANVTGSYGAACNKLSTFTQFSFMVYNSEKNQPTEEKVDCI", "length": 346 }, "evidence": [ { "id": "F1NQI0", "url": "https://omabrowser.org/oma/group/F1NQI0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P30919-1", "protein_name": "N(4)-(Beta-N-acetylglucosaminyl)-L-asparaginase", "gene_name": "Aga", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MARKWNLPFLLLPLVLGIPLVRGSNPLPLVVNTWPFKNATEAAWWTLVSGGSALDAVEKGCAMCEKEQCGGTVGFGGSPDEVGETTLDAMIMDGTAMDVGAVGGLRRIKNAIGVARKVLEHTTHTLLVGDSATKFAVSMGFTSEDLSTNTSRALHSDWLSRNCQPNYWRNVIPDPSKYCGPYKPPDFLEQNNRAHKEVDIHSHDTIGMVVIHKTGHTAAGTSTNGLKFKIPGRVGDSPIPGAGAYADDMAGAAAATGDGDTLLRFLPSYQAVEYMRGGDDPARACQKVISRIQKYYPKFFGAVICANVTGSYGAACNRLPTFTQFSFMVYNSLHNQAIEEKVDCM", "length": 345 }, "evidence": [ { "id": "F1NQI0", "url": "https://omabrowser.org/oma/group/F1NQI0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q56W64-1", "protein_name": "Probable isoaspartyl peptidase/L-asparaginase 3", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MARSDVLIFVSTLLLFLSLLTVADAELVKSDKFPVVVSTWPFLEAVRAAWRAVDNGSSAVEAVVEGCSACEELRCDGTVGPGGSPDENGETMIDALVMDGVTMEVGAVAAMRYVKDGIRAAHLVMKYSQHTLLAGEGASAFAISMGLPGPMNLSSPESVKKWSDWKENQCQPNFRKNVVPANDCGPYKPNNSAMNVFVDKSTESCEMGAIEYKPPLVGPHNHDTISMAVIDRMGHIAVGTSTNGATYKIPGRVGDGPIVGSSAYADDEVGGCGATGDGDTMMRFLPCYQVVESMRQGMKPEEAAKDAISRIARKFPDFVGAVVAVDKNGSHAGACYGWTFQYSVQNPDMNDVQVFTVLP", "length": 359 }, "evidence": [ { "id": "F1NQI0", "url": "https://omabrowser.org/oma/group/F1NQI0/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q64191-1", "protein_name": "N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase", "gene_name": "Aga", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MERKSNLSLLLLLLVLGMPLVRGSSPLPLVVNTWPFKNATEAAWWTLLSGGSALDAVENGCAVCEKEQCDGTVGFGGSPDEGGETTLDAMIMDGTAMDVGAVGGLRRIKNAIGVARRVLEHTTHTLLVGDSATKFAESMGFTNEDLSTKTSRDLHSDWLSRNCQPNYWRNVIPDPSKYCGPYKPSGFLKQSISPHKEEVDIHSHDTIGMVVIHKTGHTAAGTSTNGIKFKIPGRVGDSPIPGAGAYADDTAGAAAATGDGDTLLRFLPSYQAVEYMRGGDDPAIACQKVILRIQKYYPNFFGAVICASVNGSYGAACNKLPTFTQFSFMVSNSLHNEPTEKKVDCI", "length": 346 }, "evidence": [ { "id": "F1NQI0", "url": "https://omabrowser.org/oma/group/F1NQI0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8MR45-1", "protein_name": "Putative N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase CG1827", "gene_name": "", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MRRHLRASLWILCLATMAFSILAAVNTSPKPTLTSAFSGKAGTTAVKANKTTGELLPMVINTWNFTAANVLAWRILKQSKGGLRQTRNAVVEGCSKCEKLQCDRTVGYGGSPDELGETTLDAMVMDGATMDVGAVAGLRRIKDAIKVARHVLEHTQHTMLVGDAASAFANAMGFESESLVTPESKDMWLQWTAENCQPNFWKNVHPDPKVSCGPYKPRPTPLTRWKEDRARNEYEIGRKNHDTIGMIAIDVESNIHAGTSTNGARHKIPGRVGDSPIPGAGAYADNEVGAAVATGDGDVMMRFLPSLLAVETMRAGKPPAEAAQEGLRRILKHHKDFMGALIAVDRLGNYGAACYGLAEFPFMVSSPAGADGPTRLETVKCIGGQDKVNIVAL", "length": 393 }, "evidence": [ { "id": "F1NQI0", "url": "https://omabrowser.org/oma/group/F1NQI0/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "F1NQI0", "url": "https://www.uniprot.org/uniprotkb/F1NQI0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "peptidase activity", "id": "GO:0008233", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008233", "evidence": [ { "database": "UniProtKB", "id": "F1NQI0", "url": "https://www.uniprot.org/uniprotkb/F1NQI0" } ], "pmid": "" }, { "name": "N4-(beta-N-acetylglucosaminyl)-L-asparaginase activity", "id": "GO:0003948", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003948", "evidence": [ { "database": "UniProtKB", "id": "F1NQI0", "url": "https://www.uniprot.org/uniprotkb/F1NQI0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "F1NQI0", "url": "https://www.uniprot.org/uniprotkb/F1NQI0" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1NQI0", "url": "https://www.uniprot.org/uniprotkb/F1NQI0" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "F1NQI0", "url": "https://www.uniprot.org/uniprotkb/F1NQI0" } ], "pmid": "" }, { "name": "lysosome", "id": "GO:0005764", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005764", "evidence": [ { "database": "UniProtKB", "id": "F1NQI0", "url": "https://www.uniprot.org/uniprotkb/F1NQI0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 160, "end_pos": 162, "annotation": "n_glycosylation_sequon" }, { "start_pos": 307, "end_pos": 309, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "11544", "name": "", "equation": "N(4)-(beta-N-acetyl-D-glucosaminyl)-L-asparagine + H2O = N-acetyl-beta-D-glucosaminylamine + L-aspartate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1NQI0-1" ], "evidence": [ { "id": "11544", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/11544" } ] }, { "id": "R-GGA-6798751", "name": "Exocytosis of azurophil granule lumen proteins", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "extracellular region, azurophil granule lumen", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0X868-1", "A0A8V0XNR7-1", "A0A8V1AFG6-1", "A2JDL7-1", "F1NI04-1", "F1NML7-1", "F1NQI0-1", "A0A1D5PSE5-1", "P27043-1", "P30374-1", "A0A1D5PN36-1", "A0A1L1RSD2-1", "Q90629-1", "A0A8V0XXM5-1", "A0A8V0ZN26-1", "A0A8V1A4Q4-1", "A0A1D5PM49-1", "A0A8V0YHC8-1", "A0A8V0YL25-1", "A0A8V0YSD2-1", "E1BS94-1", "E1BSN7-1", "A0A8V0YVV2-1", "A0A8V0YW12-1", "A0A8V0Z0Z6-1", "A0A1D5PJC6-1", "A0A8V1AEN9-1", "F1NTQ2-1", "A0A1D5PXN4-1", "P00698-1", "A0A8V0Y6N9-1", "A0A8V0Y726-1", "A0A8V0ZQV0-1" ], "evidence": [ { "id": "R-GGA-6798751", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6798751" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A1D5PJC6", "gene_name": "CPPED1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A1D5PJC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PJC6" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A1D5PJC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PJC6" } ] } ] }, { "uniprot_ac": "A0A1D5PM49", "gene_name": "GALNS", "activity": [ { "ec_number": "3.1.6.4", "activity": "Hydrolysis of the 6-sulfate groups of the N-acetyl-D-galactosamine 6-sulfate units of chondroitin sulfate and of the D-galactose 6-sulfate units of keratan sulfate.", "evidence": [ { "id": "A0A1D5PM49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PM49" } ] }, { "ec_number": "3.1.6.4", "activity": "", "evidence": [ { "id": "A0A1D5PM49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PM49" } ] } ] }, { "uniprot_ac": "A0A1D5PN36", "gene_name": "LOC107054567", "activity": [ { "ec_number": "3.4.21.4", "activity": "Preferential cleavage: Arg-|-Xaa, Lys-|-Xaa.", "evidence": [ { "id": "A0A1D5PN36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PN36" } ] }, { "ec_number": "3.4.21.4", "activity": "", "evidence": [ { "id": "A0A1D5PN36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PN36" } ] } ] }, { "uniprot_ac": "A0A1D5PSE5", "gene_name": "ACLY", "activity": [ { "ec_number": "2.3.3.8", "activity": "oxaloacetate + acetyl-CoA + ADP + phosphate = citrate + ATP + CoA.", "evidence": [ { "id": "A0A1D5PSE5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PSE5" } ] }, { "ec_number": "2.3.3.8", "activity": "", "evidence": [ { "id": "A0A1D5PSE5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PSE5" } ] } ] }, { "uniprot_ac": "A0A1D5PXN4", "gene_name": "PRKCD", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PXN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PXN4" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A1D5PXN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PXN4" } ] } ] }, { "uniprot_ac": "A0A1L1RSD2", "gene_name": "GUSB", "activity": [ { "ec_number": "3.2.1.31", "activity": "a beta-D-glucuronoside + H2O = D-glucuronate + an alcohol.", "evidence": [ { "id": "A0A1L1RSD2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RSD2" } ] }, { "ec_number": "3.2.1.31", "activity": "", "evidence": [ { "id": "A0A1L1RSD2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RSD2" } ] } ] }, { "uniprot_ac": "A0A8V0X868", "gene_name": "GGH", "activity": [ { "ec_number": "3.4.19.9", "activity": "(6S)-5,6,7,8-tetrahydrofolyl-(gamma-L-Glu)(n) + (n-1) H2O = (6S)-5,6,7,8-tetrahydrofolate + (n-1) L-glutamate.", "evidence": [ { "id": "A0A8V0X868", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X868" } ] }, { "ec_number": "3.4.19.9", "activity": "", "evidence": [ { "id": "A0A8V0X868", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X868" } ] } ] }, { "uniprot_ac": "A0A8V0XNR7", "gene_name": "CTSC", "activity": [ { "ec_number": "3.4.14.1", "activity": "Release of an N-terminal dipeptide, Xaa-Yaa-|-Zaa-, except when Xaa is Arg or Lys, or Yaa or Zaa is Pro.", "evidence": [ { "id": "A0A8V0XNR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNR7" } ] }, { "ec_number": "3.4.14.1", "activity": "", "evidence": [ { "id": "A0A8V0XNR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNR7" } ] } ] }, { "uniprot_ac": "A0A8V0XXM5", "gene_name": "ARSA", "activity": [ { "ec_number": "3.1.6.8", "activity": "an N-acyl-1-beta-D-(3-O-sulfo)-galactosyl-sphing-4-enine + H2O = a beta-D-galactosyl-(1<->1')-N-acylsphing-4-enine + sulfate + H(+).", "evidence": [ { "id": "A0A8V0XXM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XXM5" } ] }, { "ec_number": "3.1.6.8", "activity": "", "evidence": [ { "id": "A0A8V0XXM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XXM5" } ] } ] }, { "uniprot_ac": "A0A8V0Y6N9", "gene_name": "NAPRT", "activity": [ { "ec_number": "6.3.4.21", "activity": "5-phospho-alpha-D-ribose 1-diphosphate + nicotinate + ATP + H2O = nicotinate beta-D-ribonucleotide + ADP + phosphate + diphosphate.", "evidence": [ { "id": "A0A8V0Y6N9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y6N9" } ] }, { "ec_number": "6.3.4.21", "activity": "", "evidence": [ { "id": "A0A8V0Y6N9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y6N9" } ] } ] }, { "uniprot_ac": "A0A8V0Y726", "gene_name": "TXNDC5", "activity": [ { "ec_number": "5.3.4.1", "activity": "Catalyzes the rearrangement of -S-S- bonds in proteins.", "evidence": [ { "id": "A0A8V0Y726", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y726" } ] }, { "ec_number": "5.3.4.1", "activity": "", "evidence": [ { "id": "A0A8V0Y726", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y726" } ] } ] }, { "uniprot_ac": "A0A8V0YHC8", "gene_name": "VCP", "activity": [ { "ec_number": "3.6.4.6", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YHC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHC8" } ] }, { "ec_number": "3.6.4.6", "activity": "", "evidence": [ { "id": "A0A8V0YHC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHC8" } ] } ] }, { "uniprot_ac": "A0A8V0YL25", "gene_name": "PRDX6", "activity": [ { "ec_number": "1.11.1.27", "activity": "a hydroperoxide + 2 glutathione = an alcohol + glutathione disulfide + H2O.", "evidence": [ { "id": "A0A8V0YL25", 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NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052573.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040515391", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040515391" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NGF2", "url": "https://www.uniprot.org/uniprotkb/F1NGF2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CLCN4", "url": "https://www.uniprot.org/uniprotkb/F1NGF2", "locus": { "chromosome": "1", "start_pos": 124989144, "end_pos": 125026173, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010002023", "url": "https://www.ensembl.org/id/ENSGALG00010002023" } ] } } ], "crossref": [ { "id": "F1NGF2", "url": "https://alphafold.ebi.ac.uk/entry/F1NGF2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000016607", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000016607", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd03684", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03684", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd04591", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04591", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "428005", "url": "https://www.ncbi.nlm.nih.gov/gene/428005", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000644", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000644", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001807", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001807", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002246", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002246", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014743", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014743", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046342", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046342", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:428005", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:428005", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "TDWVHDT", "url": "https://omabrowser.org/oma/group/TDWVHDT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XDV5", "url": "https://www.orthodb.org/?gene=A0A8V0XDV5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NGF2", "url": "https://www.orthodb.org/?gene=F1NGF2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45711", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45711", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45711:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45711:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00571", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00571", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00654", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00654", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-2672351", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2672351", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_040515391", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040515391", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0XDV5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XDV5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XDV5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XDV5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NGF2", "url": "https://www.uniprot.org/uniprotkb/F1NGF2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NGF2-1", "url": "https://www.uniprot.org/uniprotkb/F1NGF2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDPNMVNAGEMNGSGNLMDFLDEPFPDVGTYEDFHTIDWLREKSRDTDRHRKITSKSKESIWEFIKSLLDAWSGWVVMLLIGLLAGTLAGVIDLAVDWMTDLKEGVCLSAFWYSHEQCCWTSNETTFDDRDKCPQWQKWSELLVNQSEGASAYILNYFLYILWALCFAFLAVSLVRVFAPYACGSGIPEIKTILSGFIIRGYLGKWTLLIKTVTLVLVVSSGLSLGKEGPLVHVACCCGNFFSSLFSKYSKNEGKRREVLSAAAAAGVSVAFGAPIGGVLFSLEEVSYYFPLKTLWRSFFAALVAAFTLRSINPFGNSRLVLFYVEYHTPWYMAELFPFILLGVFGGLWGTLFIRCNIAWCRRRKTTRLGKYPVLEVIVITAITAIIAYPNPYTRRSTSELISELFNDCGALESSQLCDYINDPNMTRPVDDIPDRPAGPGVYTAMWQLALALVFKIVITIFTFGMKIPSGLFIPSMAVGAMAGRMVGIGVEQLAYHHHDWIIFRNWCRPGADCVTPGLYAMVGAAACLGGVTRMTVSLVVIMFELTGGLEYIVPLMAAAVTSKWVADAFGKEGIYEAHIHLNGYPFLDVKDEFTHRTLATDVMRPRRGEAPLSVLTQDSMTVEDVETLIKETDYNGFPVVVSKDSERLIGFAQRRELILAIKNARQRQDGVVSNSIVYFTEDPPELPPNSPHPLKLRRILNLSPFTVTDHTPMETVVDIFRKLGLRQCLVTRSGRLLGIITKKDVLRHMAQMANQDPESIMFN", "length": 764, "header": "tr|F1NGF2-1|F1NGF2_CHICK Isoform 1 of Chloride channel protein OS=Gallus gallus OX=9031 GN=CLCN4 PE=3 SV=3 CANONICAL=F1NGF2-1" }, "isoforms": [ { "isoform_ac": "A0A8V0XDV5-1", "url": "https://www.uniprot.org/uniprotkb/F1NGF2/entry#A0A8V0XDV5-1", "sequence": { "sequence": "MVNAGEMNGSGNLMDFLDEPFPDVGTYEDFHTIDWLREKSRDTDRHRKITSKSKESIWEFIKSLLDAWSGWVVMLLIGLLAGTLAGVIDLAVDWMTDLKEGVCLSAFWYSHEQCCWTSNETTFDDRDKCPQWQKWSELLVNQSEGASAYILNYFLYILWALCFAFLAVSLVRVFAPYACGSGIPEIKTILSGFIIRGYLGKWTLLIKTVTLVLVVSSGLSLGKEGPLVHVACCCGNFFSSLFSKYSKNEGKRREVLSAAAAAGVSVAFGAPIGGVLFSLEEVSYYFPLKTLWRSFFAALVAAFTLRSINPFGNSRLVLFYVEYHTPWYMAELFPFILLGVFGGLWGTLFIRCNIAWCRRRKTTRLGKYPVLEVIVITAITAIIAYPNPYTRRSTSELISELFNDCGALESSQLCDYINDPNMTRPVDDIPDRPAGPGVYTAMWQLALALVFKIVITIFTFGMKIPSGLFIPSMAVGAMAGRMVGIGVEQLAYHHHDWIIFRNWCRPGADCVTPGLYAMVGAAACLGGVTRMTVSLVVIMFELTGGLEYIVPLMAAAVTSKWVADAFGKEGIYEAHIHLNGYPFLDVKDEFTHRTLATDVMRPRRGEAPLSVLTQDSMTVEDVETLIKETDYNGFPVVVSKDSERLIGFAQRRELILAIKNARQRQDGVVSNSIVYFTEDPPELPPNSPHPLKLRRILNLSPFTVTDHTPMETVVDIFRKLGLRQCLVTRSGRLLGIITKKDVLRHMAQMANQDPESIMFN", "length": 760, "header": "tr|A0A8V0XDV5-1|F1NGF2_CHICK Computationally mapped isoform of Chloride channel protein OS=Gallus gallus OX=9031 GN=CLCN4 PE=3 SV=1 CANONICAL=F1NGF2-1" }, "locus": { "chromosome": "1", "start_pos": 125012420, "end_pos": 124989731, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010004577.1", "url": "https://www.ensembl.org/id/ENSGALT00010004577.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010002782.1", "url": "https://www.ensembl.org/id/ENSGALP00010002782.1" } ] } }, { "isoform_ac": "F1NGF2-1", "url": "https://www.uniprot.org/uniprotkb/F1NGF2/entry#F1NGF2-1", "sequence": { "sequence": "MDPNMVNAGEMNGSGNLMDFLDEPFPDVGTYEDFHTIDWLREKSRDTDRHRKITSKSKESIWEFIKSLLDAWSGWVVMLLIGLLAGTLAGVIDLAVDWMTDLKEGVCLSAFWYSHEQCCWTSNETTFDDRDKCPQWQKWSELLVNQSEGASAYILNYFLYILWALCFAFLAVSLVRVFAPYACGSGIPEIKTILSGFIIRGYLGKWTLLIKTVTLVLVVSSGLSLGKEGPLVHVACCCGNFFSSLFSKYSKNEGKRREVLSAAAAAGVSVAFGAPIGGVLFSLEEVSYYFPLKTLWRSFFAALVAAFTLRSINPFGNSRLVLFYVEYHTPWYMAELFPFILLGVFGGLWGTLFIRCNIAWCRRRKTTRLGKYPVLEVIVITAITAIIAYPNPYTRRSTSELISELFNDCGALESSQLCDYINDPNMTRPVDDIPDRPAGPGVYTAMWQLALALVFKIVITIFTFGMKIPSGLFIPSMAVGAMAGRMVGIGVEQLAYHHHDWIIFRNWCRPGADCVTPGLYAMVGAAACLGGVTRMTVSLVVIMFELTGGLEYIVPLMAAAVTSKWVADAFGKEGIYEAHIHLNGYPFLDVKDEFTHRTLATDVMRPRRGEAPLSVLTQDSMTVEDVETLIKETDYNGFPVVVSKDSERLIGFAQRRELILAIKNARQRQDGVVSNSIVYFTEDPPELPPNSPHPLKLRRILNLSPFTVTDHTPMETVVDIFRKLGLRQCLVTRSGRLLGIITKKDVLRHMAQMANQDPESIMFN", "length": 764, "header": "tr|F1NGF2-1|F1NGF2_CHICK Isoform 1 of Chloride channel protein OS=Gallus gallus OX=9031 GN=CLCN4 PE=3 SV=3 CANONICAL=F1NGF2-1" }, "locus": { "chromosome": "1", "start_pos": 125025974, "end_pos": 124989731, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010004583.1", "url": "https://www.ensembl.org/id/ENSGALT00010004583.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010002789.1", "url": "https://www.ensembl.org/id/ENSGALP00010002789.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 516, "start_aa": "Thr", "end_pos": 516, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr516", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:428005", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:428005", "resource": "KEGG Pathway" }, { "id": "R-GGA-2672351", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2672351", "resource": "Reactome", "description": "Stimuli-sensing channels" } ], "orthologs": [ { "uniprot_canonical_ac": "P51793-1", "protein_name": "H(+)/Cl(-) exchange transporter 4", "gene_name": "CLCN4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVNAGAMSGSGNLMDFLDEPFPDVGTYEDFHTIDWLREKSRDTDRHRKITSKSKESIWEFIKSLLDAWSGWVVMLLIGLLAGTLAGVIDLAVDWMTDLKEGVCLSAFWYSHEQCCWTSNETTFEDRDKCPLWQKWSELLVNQSEGASAYILNYLMYILWALLFAFLAVSLVRVFAPYACGSGIPEIKTILSGFIIRGYLGKWTLLIKTVTLVLVVSSGLSLGKEGPLVHVACCCGNFFSSLFSKYSKNEGKRREVLSAAAAAGVSVAFGAPIGGVLFSLEEVSYYFPLKTLWRSFFAALVAAFTLRSINPFGNSRLVLFYVEYHTPWYMAELFPFILLGVFGGLWGTLFIRCNIAWCRRRKTTRLGKYPVLEVIVVTAITAIIAYPNPYTRQSTSELISELFNDCGALESSQLCDYINDPNMTRPVDDIPDRPAGVGVYTAMWQLALALIFKIVVTIFTFGMKIPSGLFIPSMAVGAIAGRMVGIGVEQLAYHHHDWIIFRNWCRPGADCVTPGLYAMVGAAACLGGVTRMTVSLVVIMFELTGGLEYIVPLMAAAVTSKWVADAFGKEGIYEAHIHLNGYPFLDVKDEFTHRTLATDVMRPRRGEPPLSVLTQDSMTVEDVETLIKETDYNGFPVVVSRDSERLIGFAQRRELILAIKNARQRQEGIVSNSIMYFTEEPPELPANSPHPLKLRRILNLSPFTVTDHTPMETVVDIFRKLGLRQCLVTRSGRLLGIITKKDVLRHMAQMANQDPESIMFN", "length": 760 }, "evidence": [ { "id": "F1NGF2", "url": "https://omabrowser.org/oma/group/F1NGF2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P51794-1", "protein_name": "H(+)/Cl(-) exchange transporter 4", "gene_name": "Clcn4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDFLDEPFPDVGTYEDFHTIDWLREKSRDTDRHRKITSKSKESIWEFIKSLLDAWSGWVVMLLIGLLAGTLAGVIDLAVDWMTDLKEGVCLSAFWYSHEQCCWTSNETTFEDRDKCPLWQKWSELLLSQSEGASAYILNYLMYILWALLFAFLAVSLVRVFAPYACGSGIPEIKTILSGFIIRGYLGKWTLLIKTVTLVLVVSSGLSLGKEGPLVHVACCCGNFFSSLFSKYSKNEGKRREVLSAAAAAGVSVAFGAPIGGVLFSLEEVSYYFPLKTLWRSFFAALVAAFTLRSINPFGNSRLVLFYVEYHTPWYMAELFPFILLGVFGGLWGTVFTRCNIAWCRRRKTTRLGKYPVLEVIVVTAITAIIAYPNPYTRQSTSELISELFNDCGALESSQLCDYINDPNMTRPVDDIPDRPAGVGVYTAMWQLALALIFKIVITIFTFGMKIPSGLFIPSMAVGAMAGRMVGIGVEQLAYHHHDWIIFRNWCRPGADCVTPGLYAMVGAAACLGGVTRMTVSLVVIMFELTGGLEYIVPLMAAAVTSKWVADAFGKEGIYEAHIHLNGYPFLDVKDEFTHRTLATDVMRPRRGEPPLSVLTQDSMTVEDVETLIKETDYNGFPVVVSRDSERLIGFAQRRELILAIKNARQRQEGIVSNSIMYFTEEPPELPANSPHPLKLRRILNLSPFTVTDHTPMETVVDIFRKLGLRQCLVTRSGRLLGIITKKDVLRHMAQMANQDPESIIFN", "length": 747 }, "evidence": [ { "id": "F1NGF2", "url": "https://omabrowser.org/oma/group/F1NGF2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q61418-1", "protein_name": "H(+)/Cl(-) exchange transporter 4", "gene_name": "Clcn4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDFLEEPFPDVGTYEDFHTIDWLREKSRDTDRHRKITSKSKESIWEFIKSLLDAWSGWVVMLLIGLLAGTLAGVIDLAVDWMTDLKEGVCLSAFWYSHEQCCWTSNETTFEDRDKCPLWQKWSELLLSQSEGASAYILNYLMYILWALLFAFLAVSLVRVFAPYACGSGIPEIKTILSGFIIRGYLGKWTLLIKTVTLVLVVSSGLSLGKEGPLVHVACCCGNFFSSLFSKYSKNEGKRREVLSAAAAAGVSVAFGAPIGGVLFSLEEVSYYFPLKTLWRSFFAALVAAFTLRSINPFGNSRLVLFYVEYHTPWYMAELFPFILLGVFGGLWGTLFTRCNIAWCRRRKTTRLGRYPVLEVIAVTAVTAIVAYPNPYTRQSTSELISELFNDCGALESSQLCDYINDPNMTRPVDDIPDRPAGVGVYTAMWQLALALIFKIVITIFTFGMKIPSGLFIPSMAVGAMAGRMVGIGVEQLAYHHHDWIIFRNWCRPGADCVTPGLYAMVGAAACLGGVTRMTVSLVVIMFELTGGLEYIVPLMAAAVTSKWVADAFGKEGIYEAHIHLNGYPFLDVKDEFTHRTLATDVMRPRRGEPPLSVLTQDSMTVEDVETLIKETDYNGFPVLVSRDSERLIGFAQRRELILAIKNARQRQEGIVSNSIMYFTEEPPELPANSPHPLKLRRILNLSPFTVTDHTPMETVVDIFRKLGLRQCLVTRSGRLLGIITKKDVLRHMAQMANQDPESIMFN", "length": 747 }, "evidence": [ { "id": "F1NGF2", "url": "https://omabrowser.org/oma/group/F1NGF2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "F1NGF2", "url": "https://www.uniprot.org/uniprotkb/F1NGF2" } ], "pmid": "" }, { "name": "antiporter activity", "id": "GO:0015297", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015297", "evidence": [ { "database": "UniProtKB", "id": "F1NGF2", "url": "https://www.uniprot.org/uniprotkb/F1NGF2" } ], "pmid": "" }, { "name": "voltage-gated chloride channel activity", "id": "GO:0005247", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005247", "evidence": [ { "database": "UniProtKB", "id": "F1NGF2", "url": "https://www.uniprot.org/uniprotkb/F1NGF2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 8, "go_terms": [ { "name": "endosome membrane", "id": "GO:0010008", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010008", "evidence": [ { "database": "UniProtKB", "id": "F1NGF2", "url": "https://www.uniprot.org/uniprotkb/F1NGF2" } ], "pmid": "" }, { "name": "early endosome", "id": "GO:0005769", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005769", "evidence": [ { "database": "UniProtKB", "id": "F1NGF2", "url": "https://www.uniprot.org/uniprotkb/F1NGF2" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "F1NGF2", "url": "https://www.uniprot.org/uniprotkb/F1NGF2" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F1NGF2", "url": "https://www.uniprot.org/uniprotkb/F1NGF2" } ], "pmid": "" }, { "name": "recycling endosome", "id": "GO:0055037", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055037", "evidence": [ { "database": "UniProtKB", "id": "F1NGF2", "url": "https://www.uniprot.org/uniprotkb/F1NGF2" } ], "pmid": "" }, { "name": "lysosomal membrane", "id": "GO:0005765", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005765", "evidence": [ { "database": "UniProtKB", "id": "F1NGF2", "url": "https://www.uniprot.org/uniprotkb/F1NGF2" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "F1NGF2", "url": "https://www.uniprot.org/uniprotkb/F1NGF2" } ], "pmid": "" }, { "name": "synaptic vesicle", "id": "GO:0008021", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008021", "evidence": [ { "database": "UniProtKB", "id": "F1NGF2", "url": "https://www.uniprot.org/uniprotkb/F1NGF2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 123, "end_pos": 125, "annotation": "n_glycosylation_sequon" }, { "start_pos": 12, "end_pos": 14, "annotation": "n_glycosylation_sequon" }, { "start_pos": 145, "end_pos": 147, "annotation": "n_glycosylation_sequon" }, { "start_pos": 425, "end_pos": 427, "annotation": "n_glycosylation_sequon" }, { "start_pos": 702, "end_pos": 704, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1NGF2-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 764, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1NGF2-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1NGF2" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 516 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 123, "end_pos": 125 }, { "start_pos": 12, "end_pos": 14 }, { "start_pos": 145, "end_pos": 147 }, { "start_pos": 425, "end_pos": 427 }, { "start_pos": 702, "end_pos": 704 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1P138-1", "uniprot_ac": "F1P138", "uniprot_id": "F1P138_CHICK", "mass": { "chemical_mass": 41265.0, "monoisotopic_mass": 41265.0 }, "refseq": { "ac": "XP_420574", "name": "protein phosphatase 1K, mitochondrial", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_420574" }, "gene_names": [ { "name": "PPM1K", "type": "recommended", "evidence": [ { "id": "F1P138", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P138" } ] }, { "name": "PPM1K", "type": "synonym", "evidence": [ { "id": "XP_420574", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_420574" } ] } ], "protein_names": [ { "name": "protein-serine/threonine phosphatase", "type": "recommended", "evidence": [ { "id": "F1P138", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P138/entry#names_and_taxonomy" } ] }, { "name": "3.1.3.16", "type": "synonym", "evidence": [ { "id": "F1P138", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P138/entry#names_and_taxonomy" } ] }, { "name": "protein phosphatase 1K, mitochondrial", "type": "synonym", "evidence": [ { "id": "XP_420574", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_420574" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052535.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 19, 2013 this sequence version replaced XP_420574.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_420574", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_420574" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1P138", "url": "https://www.uniprot.org/uniprotkb/F1P138" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PPM1K", "url": "https://www.uniprot.org/uniprotkb/F1P138", "locus": { "chromosome": "4", "start_pos": 46574451, "end_pos": 46589365, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010003531", "url": "https://www.ensembl.org/id/ENSGALG00010003531" } ] } } ], "crossref": [ { "id": "F1P138", "url": "https://alphafold.ebi.ac.uk/entry/F1P138", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000011266", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000011266", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00143", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00143", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "422614", "url": "https://www.ncbi.nlm.nih.gov/gene/422614", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000222", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000222", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001932", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001932", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015655", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015655", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036457", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036457", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:422614", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422614", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CHTHMKK", "url": "https://omabrowser.org/oma/group/CHTHMKK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XDZ1", "url": "https://www.orthodb.org/?gene=A0A8V0XDZ1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XE01", "url": "https://www.orthodb.org/?gene=A0A8V0XE01", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XGS1", "url": "https://www.orthodb.org/?gene=A0A8V0XGS1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1P138", "url": "https://www.orthodb.org/?gene=F1P138", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47992", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47992", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00481", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00481", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-70895", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-70895", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_420574", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_420574", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0XDZ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XDZ1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XDZ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XDZ1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XE01", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XE01", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XE01-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XE01-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XGS1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XGS1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XGS1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XGS1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1P138", "url": "https://www.uniprot.org/uniprotkb/F1P138", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1P138-1", "url": "https://www.uniprot.org/uniprotkb/F1P138-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSTAALIHLVRNGGYQVRRRALLTSRLLQDEKRTTAECCISTSERRASRFDPDGSGRPATWDTFGIWDNRIDEPILLPPSIKYGKPIPKVSLSKVGCASHIGKRKENEDRFDYAQLTEDVLYFAVYDGHGGAAAADFCAKNMERYIKEFAAQEENLEKVLNDAFLEINKAYERHAQLSADATLMNSGTTATVALLRDGIELVVASVGDSRALLCRKGKAMKLTIDHTPERKEEKERIRKCGGFVAWNSLGQPHVNGRLAMTRSIGDLDLKSSGVIAQPETKRVQLHHADDGFLVLTTDGINFMVNSQEICDFINQCHDPAEAAHVVTEQAMQYGTEDNSTVVIVPFGAWGKYKNGEINFSFSRSFASSGRWA", "length": 372, "header": "tr|F1P138-1|F1P138_CHICK Isoform 1 of protein-serine/threonine phosphatase OS=Gallus gallus OX=9031 GN=PPM1K PE=3 SV=1 CANONICAL=F1P138-1" }, "isoforms": [ { "isoform_ac": "A0A8V0XDZ1-1", "url": "https://www.uniprot.org/uniprotkb/F1P138/entry#A0A8V0XDZ1-1", "sequence": { "sequence": "MFLQAPSFCLSLKEIHCKARFQNTRCNYDLNLENTMARRSSTELSISRTFQLLHLFYPYESLRRQVMSTAALIHLVRNGGYQVRRRALLTSRLLQDEKRTTAECCISTSERRASRFDPDGSGRPATWDTFGIWDNRIDEPILLPPSIKYGKPIPKVSLSKVGCASHIGKRKENEDRFDYAQLTEDVLYFAVYDGHGGAAAADFCAKNMERYIKEFAAQEENLEKVLNDAFLEINKAYERHAQLSADERITRAAEYERENNSQEENEIRCGKAGTSPFRFP", "length": 280, "header": "tr|A0A8V0XDZ1-1|A0A8V0XDZ1_CHICK Computationally mapped isoform of Protein phosphatase, Mg2+/Mn2+ dependent 1K OS=Gallus gallus OX=9031 GN=PPM1K PE=4 SV=1 CANONICAL=F1P138-1" }, "locus": { "chromosome": "4", "start_pos": 46587942, "end_pos": 46584811, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010008237.1", "url": "https://www.ensembl.org/id/ENSGALT00010008237.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010004893.1", "url": "https://www.ensembl.org/id/ENSGALP00010004893.1" } ] } }, { "isoform_ac": "A0A8V0XE01-1", "url": "https://www.uniprot.org/uniprotkb/F1P138/entry#A0A8V0XE01-1", "sequence": { "sequence": "MSTAALIHLVRNGGYQVRRRALLTSRLLQDEKRTTAECCISTSERRASRFDPDGSGRPATWDTFGIWDNRIDEPILLPPSIKYGKPIPKVSLSKVGCASHIGKRKENEDRFDYAQLTEDVLYFAVYDGHGGAAAADFCAKNMERYIKEFAAQEENLEKVLNDAFLEINKAYERHAQLSADATLMNSGTTATVALLRDGIELVVASVGDSRALLCRKGKAMKLTIDHTPERKEEKERIRKCGGFVAWNSLGQPHVNGRLAMTRSIGDLDLKSSGVIAQPETKRVQLHHADDGFLVLTTDGINFMVNSQEICDFINQCHDPAEAAHVVTEQYGTEDNSTVVIVPFGAWGKYKNGEINFSFSRSFASSGRWA", "length": 369, "header": "tr|A0A8V0XE01-1|F1P138_CHICK Computationally mapped isoform of protein-serine/threonine phosphatase OS=Gallus gallus OX=9031 GN=PPM1K PE=3 SV=1 CANONICAL=F1P138-1" }, "locus": { "chromosome": "4", "start_pos": 46586588, "end_pos": 46575927, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010008257.1", "url": "https://www.ensembl.org/id/ENSGALT00010008257.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010004903.1", "url": "https://www.ensembl.org/id/ENSGALP00010004903.1" } ] } }, { "isoform_ac": "A0A8V0XGS1-1", "url": "https://www.uniprot.org/uniprotkb/F1P138/entry#A0A8V0XGS1-1", "sequence": { "sequence": "MFLQAPSFCLSLKEIHCKARFQNTRCNYDLNLENTMARRSSTELSISRTFQLLHLFYPYESLRRQVMSTAALIHLVRNGGYQVRRRALLTSRLLQDEKRTTAECCISTSERRASRFDPDGSGRPATWDTFGIWDNRIDEPILLPPSIKYGKPIPKVSLSKVGCASHIGKRKENEDRFDYAQLTEDVLYFAVYDGHGGAAAADFCAKNMERYIKEFAAQEENLEKVLNDAFLEINKAYERHAQLSADDTVPGQQL", "length": 254, "header": "tr|A0A8V0XGS1-1|A0A8V0XGS1_CHICK Computationally mapped isoform of Protein phosphatase, Mg2+/Mn2+ dependent 1K OS=Gallus gallus OX=9031 GN=PPM1K PE=4 SV=1 CANONICAL=F1P138-1" }, "locus": { "chromosome": "4", "start_pos": 46587942, "end_pos": 46581203, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010008243.1", "url": "https://www.ensembl.org/id/ENSGALT00010008243.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010004896.1", "url": "https://www.ensembl.org/id/ENSGALP00010004896.1" } ] } }, { "isoform_ac": "F1P138-1", "url": "https://www.uniprot.org/uniprotkb/F1P138/entry#F1P138-1", "sequence": { "sequence": "MSTAALIHLVRNGGYQVRRRALLTSRLLQDEKRTTAECCISTSERRASRFDPDGSGRPATWDTFGIWDNRIDEPILLPPSIKYGKPIPKVSLSKVGCASHIGKRKENEDRFDYAQLTEDVLYFAVYDGHGGAAAADFCAKNMERYIKEFAAQEENLEKVLNDAFLEINKAYERHAQLSADATLMNSGTTATVALLRDGIELVVASVGDSRALLCRKGKAMKLTIDHTPERKEEKERIRKCGGFVAWNSLGQPHVNGRLAMTRSIGDLDLKSSGVIAQPETKRVQLHHADDGFLVLTTDGINFMVNSQEICDFINQCHDPAEAAHVVTEQAMQYGTEDNSTVVIVPFGAWGKYKNGEINFSFSRSFASSGRWA", "length": 372, "header": "tr|F1P138-1|F1P138_CHICK Isoform 1 of protein-serine/threonine phosphatase OS=Gallus gallus OX=9031 GN=PPM1K PE=3 SV=1 CANONICAL=F1P138-1" }, "locus": { "chromosome": "4", "start_pos": 46586588, "end_pos": 46575927, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010008251.1", "url": "https://www.ensembl.org/id/ENSGALT00010008251.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010004899.1", "url": "https://www.ensembl.org/id/ENSGALP00010004899.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "gga:422614", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422614", "resource": "KEGG Pathway" }, { "id": "R-GGA-70895", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-70895", "resource": "Reactome", "description": "Branched-chain amino acid catabolism" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A061HVT3-1", "protein_name": "Protein phosphatase Mn(2+)-dependent 1K", "gene_name": "Ppm1k", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MLSAALITLVRSGGNHVKKRVLLRSVLLQDNRQVTPTCYSSISEPRCSRFDPDGSGQPATWDNFGIWDNRIDEPILLPPSIKYGKPIPKISLENVGCASLIGKRKENEDRFEFAQLTEEVLYFAVYDGHGGPAAADFCHTHMKKCVMDLLPREKDLETVLTLAFLEIDKAFSSYAHLSADASLLTSGTTATVALLRDGIELVVASVGDSRALLCRKGKPMKLTTDHTPERKDEKERIKKCGGFVAWNSLGQPHVNGRLAMTRSIGDLDLKASGVIAEPETTRIKLYHADDSFLVLTTDGINFMVNSQEICDFVNQCHDPNEAAHAVTEQAIQYGTEDNSTAVVVPFGAWGKYKNSEINFSFSRSFASSGRWA", "length": 372 }, "evidence": [ { "id": "F1P138", "url": "https://omabrowser.org/oma/group/F1P138/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A286ZX57-1", "protein_name": "Protein phosphatase Mn(2+)-dependent 1K", "gene_name": "PPM1K", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSTAALITLVRRGGTQVRSRALLSGRLLQDGRWGVTPTCPGSTSEPRCSRFDPDGSGRPATWDNFGFWDNRIDEPILLPPSIKYGKPIPKVSLANVGGASQIGKRKENEDRFDFAQLTDQILYFAVYDGHGGPAAADFCHTHMEQCILDLLPKEQDLETVLTLAFLEIDKAFARHAHLSADATLLTSGTTATVALLRDGIELVVASVGDSRAILCRKGKPMKLTIDHTPERKDEKERIKKCGGFVAWNSLGQPHVNGRLAMTRSLGDLDLKTSGVIAEPETRRIKLHHADDSFLVLTTDGINFMVNSQEICDFVNQCHDPSEAAHAVTEQAIQYGTEDNTTAVVVPFGAWGKYKNSEVTFSFSRSFASSGRWA", "length": 373 }, "evidence": [ { "id": "F1P138", "url": "https://omabrowser.org/oma/group/F1P138/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8M1P874-1", "protein_name": "protein-serine/threonine phosphatase", "gene_name": "ppm1kb", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSVALLVRYATLSGSRVCSRAAFNLTNAHQEDPRRALHTPSSPRFSNSRFDPDSSGRPTTWDSFGIWDNRIDEPILLPSSIRYGKLIPKVNLSRVGSASQIGQRKENEDRYQMSQMTDNIMYFAVFDGHGGAEAADFCHKNMEKHIKDIAAEETNLEFVLTKAFLEVDKALARHLHFSADASVLSAGTTATVALLRDGIELVVGSVGDSRAMMCRKGKAVKLTVDHTPERKDEKERIRRSGGFITWNSLGQPHVNGRLAMTRSIGDFDLKATGVIAEPETKRISLHHVHDSFLALTTDGINFIMNSQEICDVINQCHDPKEAAQRISEQALQYGSEDNSTIIVVPFGAWGKHKSSEVSFSFSRSFVSSGRFA", "length": 372 }, "evidence": [ { "id": "F1P138", "url": "https://omabrowser.org/oma/group/F1P138/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A6K136-1", "protein_name": "Protein phosphatase Mn(2+)-dependent 1K", "gene_name": "Ppm1k", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLSTAFITLVRSGRNQVKKRVLLSSILLQDHRQMTPACYCSISEPRCSRFDPDGSGQPATWDNFGIWDNRIDEPILLPPSIKYGKPIPKISLENVGCASLIGKRKENEDRFGFAQLTEEVLYFAVYDGHGGPAAADFCHTHMEKCVTDLLPREKDLETVLTLAFLEIDKAFSSYAHLSADASLLTSGTTATVALLRDGVELVVASVGDSRALLCRKGKPMKLTTDHTPERKDEKERIKKCGGFVAWNSLGQPHVNGRLAMTRSIGDLDLKASGVIAEPETTRIKLYHADDSFLVLTTDGINFMVNSQEICDFVNQCHDPKEAAHAVTEQAIQYGTEDNSTAVVVPFGAWGKYKNSEITFSFSRSFASSGRWA", "length": 372 }, "evidence": [ { "id": "F1P138", "url": "https://omabrowser.org/oma/group/F1P138/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q2PC20-1", "protein_name": "Protein phosphatase Mn(2+)-dependent 1K", "gene_name": "PPM1K", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSTAALLTLVRSGGNQVRRRVLLRARGLQDDRWVMPTCHSSTSEPKWSRFDPDGSGRPATWDNFGIWDNRLEEPILLPPSIKYGKPIPKVSLQNVGSASQIGKRKENEDRFGFAQLTNEVLYFAVYDGHGGPAAADFCHTHMEKCILDLLPKEENLETVLTLAFLEIDKTFARHAHLSADATLLTSGTTATVALLRDGIELVIASVGDSRAILCRKGKPMKLTIDHTPERKDEKERIKKCGGFVAWNSLGQPHVNGRLAMTRSLGDLDLKTSGVIAEPETKRIKLHHADDSFLVLTTDGINFMVNSQEICDFVNQCHDPNEAAHAVTEQAIQYGTEDNTTAVVVPFGAWGKYKNSEITFSFSRSFASSGRWA", "length": 372 }, "evidence": [ { "id": "F1P138", "url": "https://omabrowser.org/oma/group/F1P138/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q8BXN7-1", "protein_name": "Protein phosphatase Mn(2+)-dependent 1K", "gene_name": "Ppm1k", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSAAFITLLRSGGNQVKKRVLLSSILLQDHRQATPACYFSTSEARCSRFDPDGSGQPATWDNFGIWDNRIDEPILLPPSIKYGKPIPKISLENVGCASLIGKRKENEDRFGFAQLTEEVLYFAVYDGHGGPAAADFCHTHMEKCVMDLLPREKDLETVLTLAFLEIDKAFASYAHLSADASLLTSGTTATVALLRDGVELVVASVGDSRALLCRKGKPMKLTTDHTPERKDEKERIKKFGGFVAWNSLGQPHVNGRLAMTRSIGDLDLKASGVIAEPETTRIKLYHADDSFLVLTTDGINFMVNSQEICDFVNQCHDPKEAAHSVTEQAIQYGTEDNSTAVVVPFGAWGKYKNSEITFSFSRSFASSGRWA", "length": 372 }, "evidence": [ { "id": "F1P138", "url": "https://omabrowser.org/oma/group/F1P138/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8N3J5-1", "protein_name": "Protein phosphatase Mn(2+)-dependent 1K", "gene_name": "PPM1K", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSTAALITLVRSGGNQVRRRVLLSSRLLQDDRRVTPTCHSSTSEPRCSRFDPDGSGSPATWDNFGIWDNRIDEPILLPPSIKYGKPIPKISLENVGCASQIGKRKENEDRFDFAQLTDEVLYFAVYDGHGGPAAADFCHTHMEKCIMDLLPKEKNLETLLTLAFLEIDKAFSSHARLSADATLLTSGTTATVALLRDGIELVVASVGDSRAILCRKGKPMKLTIDHTPERKDEKERIKKCGGFVAWNSLGQPHVNGRLAMTRSIGDLDLKTSGVIAEPETKRIKLHHADDSFLVLTTDGINFMVNSQEICDFVNQCHDPNEAAHAVTEQAIQYGTEDNSTAVVVPFGAWGKYKNSEINFSFSRSFASSGRWA", "length": 372 }, "evidence": [ { "id": "F1P138", "url": "https://omabrowser.org/oma/group/F1P138/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "mitochondrial matrix", "id": "GO:0005759", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005759", "evidence": [ { "database": "UniProtKB", "id": "F1P138", "url": "https://www.uniprot.org/uniprotkb/F1P138" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "F1P138", "url": "https://www.uniprot.org/uniprotkb/F1P138" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "F1P138", "url": "https://www.uniprot.org/uniprotkb/F1P138" } ], "pmid": "" }, { "name": "protein serine/threonine phosphatase activity", "id": "GO:0004722", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004722", "evidence": [ { "database": "UniProtKB", "id": "F1P138", "url": "https://www.uniprot.org/uniprotkb/F1P138" } ], "pmid": "" }, { "name": "phosphoprotein phosphatase activity", "id": "GO:0004721", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004721", "evidence": [ { "database": "UniProtKB", "id": "F1P138", "url": "https://www.uniprot.org/uniprotkb/F1P138" } ], "pmid": "" }, { "name": "manganese ion binding", "id": "GO:0030145", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030145", "evidence": [ { "database": "UniProtKB", "id": "F1P138", "url": "https://www.uniprot.org/uniprotkb/F1P138" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "branched-chain amino acid catabolic process", "id": "GO:0009083", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009083", "evidence": [ { "database": "UniProtKB", "id": "F1P138", "url": "https://www.uniprot.org/uniprotkb/F1P138" } ], "pmid": "" }, { "name": "regulation of intracellular signal transduction", "id": "GO:1902531", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902531", "evidence": [ { "database": "UniProtKB", "id": "F1P138", "url": "https://www.uniprot.org/uniprotkb/F1P138" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 338, "end_pos": 340, "annotation": "n_glycosylation_sequon" }, { "start_pos": 358, "end_pos": 360, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-GGA-5693153", "name": "PPM1K dephosphorylates p-BCKDH", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "mitochondrial matrix", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XT23-1", "F1P138-1", "A0A1D5P765-1", "A0A8V1A234-1", "A0A8V0Y1C8-1" ], "evidence": [ { "id": "R-GGA-5693153", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5693153" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A1D5P765", "gene_name": "BCKDHB", "activity": [ { "ec_number": "1.2.4.4", "activity": "N(6)-[(R)-lipoyl]-L-lysyl-[protein] + (S)-3-methyl-2-oxopentanoate + H(+) = N(6)-{(R)-S(8)-[(2S)-2-methylbutanoyl]dihydrolipoyl}-L-lysyl-[protein] + CO2.", "evidence": [ { "id": "A0A1D5P765", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P765" } ] }, { "ec_number": "1.2.4.4", "activity": "", "evidence": [ { "id": "A0A1D5P765", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P765" } ] } ] }, { "uniprot_ac": "A0A8V0XT23", "gene_name": "BCKDHA", "activity": [ { "ec_number": "1.2.4.4", "activity": "N(6)-[(R)-lipoyl]-L-lysyl-[protein] + (S)-3-methyl-2-oxopentanoate + H(+) = N(6)-{(R)-S(8)-[(2S)-2-methylbutanoyl]dihydrolipoyl}-L-lysyl-[protein] + CO2.", "evidence": [ { "id": "A0A8V0XT23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XT23" } ] }, { "ec_number": "1.2.4.4", "activity": "", "evidence": [ { "id": "A0A8V0XT23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XT23" } ] } ] }, { "uniprot_ac": "A0A8V0Y1C8", "gene_name": "DLD", "activity": [ { "ec_number": "1.8.1.4", "activity": "N(6)-[(R)-dihydrolipoyl]-L-lysyl-[protein] + NAD(+) = N(6)-[(R)-lipoyl]-L-lysyl-[protein] + NADH + H(+).", "evidence": [ { "id": "A0A8V0Y1C8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y1C8" } ] }, { "ec_number": "1.8.1.4", "activity": "", "evidence": [ { "id": "A0A8V0Y1C8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y1C8" } ] } ] }, { "uniprot_ac": "A0A8V1A234", "gene_name": "DBT", "activity": [ { "ec_number": "2.3.1.-", "activity": "", "evidence": [ { "id": "A0A8V1A234", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A234" } ] } ] }, { "uniprot_ac": "F1P138", "gene_name": "PPM1K", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F1P138", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P138" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "F1P138", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P138" } ] } ] } ], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1P138-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 372, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1P138-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1P138" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1P138", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P138" }, { "id": "PS51746", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51746" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PPM-type phosphatase", "eco_id": "ECO_0000259", "start_pos": 94, "end_pos": 346, "start_aa": "Lys", "end_aa": "Phe", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "3.1.3.16", "ec_name": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "3.1.3.16", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.16" }, { "id": "3.1.3.16", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=3.1.3.16" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 338, "end_pos": 340 }, { "start_pos": 358, "end_pos": 360 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": 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] }, { "id": "IPR004161", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004161", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009000", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009000", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009001", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009001", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015256", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015256", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044127", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044127", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044128", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044128", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050543", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050543", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:418597", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418597", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "NIGMVGH", "url": "https://omabrowser.org/oma/group/NIGMVGH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XF84", "url": "https://www.orthodb.org/?gene=A0A8V0XF84", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XHZ8", "url": "https://www.orthodb.org/?gene=A0A8V0XHZ8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NPF0", "url": "https://www.orthodb.org/?gene=F1NPF0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR42854", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR42854", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR42854:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR42854:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00009", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00009", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF03144", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03144", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF09173", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09173", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-381042", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-381042", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-72649", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-72649", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-72695", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-72695", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-72702", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-72702", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-72731", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-72731", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9840373", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9840373", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001006260", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006260", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "19669", "url": "https://www.rhea-db.org/rhea/19669", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0XF84", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XF84", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XF84-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XF84-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XHZ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XHZ8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XHZ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XHZ8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NPF0", "url": "https://www.uniprot.org/uniprotkb/F1NPF0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NPF0-1", "url": "https://www.uniprot.org/uniprotkb/F1NPF0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAGDEAGVTLGQPHLSRQDLATLDVTKLTPLSPEVISRQATINIGTIGHVAHGKSTVVKAISGVHTVRFKNELERNITIKLGYANAKIYKLDDPSCSRPECYRSCGSSTPDEFPTDIPGTKGNFKLVRHVSFVDCPGHDILMATMLNGAAVMDAALLLIAGNESCPQPQTSEHLAAIEIMKLKHILILQNKIDLVKESQAKEQYEQILAFVQGTVAEGAPIIPISAQLKYNIEVVCEYIVKKIPVPLRDFTSEPRLIVIRSFDVNKPGCEVDDLKGGVAGGSILKGVLKVGQEIEVRPGIVSKDSEGKLMCKPIFSKIVSLFAEHNDLQYAAPGGLIGVGTKIDPTLCRADRMVGQVLGAVGALPEIFTELEISYFLLRRLLGVRTEGDKKAAKVQKLSKNEVLMVNIGSLSTGGRVSAVKADLGKIVLTNPVCTEVGEKIALSRRVEKHWRLIGWGQIRRGVTIKPTVDDD", "length": 472, "header": "tr|F1NPF0-1|F1NPF0_CHICK Isoform 1 of protein-synthesizing GTPase OS=Gallus gallus OX=9031 GN=EIF2S3 PE=1 SV=1 CANONICAL=F1NPF0-1" }, "isoforms": [ { "isoform_ac": "A0A8V0XF84-1", "url": "https://www.uniprot.org/uniprotkb/F1NPF0/entry#A0A8V0XF84-1", "sequence": { "sequence": "MAGDEAGVTLGQPHLSRQDLATLDVTKLTPLSPEVISRQATINIGTIGHVAHGKSTVVKAISGVHTVRFKNELERNITIKLGYANAKIYKLDDPSCSRPECYRSCGSSTPDEFPTDIPGTKGNFKLVRHVSFVDCPGHDILMATMLNGAAVMDAALLLIAGNESCPQPQTSEHLAAIEIMKLKHILILQNKIDLVKESQAKEQYEQILAFVQVAEGAPIIPISAQLKYNIEVVCEYIVKKIPVPLRDFTSEPRLIVIRSFDVNKPGCEVDDLKGGVAGGSILKGVLKVGQEIEVRPGIVSKDSEGKLMCKPIFSKIVSLFAEHNDLQYAAPGGLIGVGTKIDPTLCRADRMVGQVLGAVGALPEIFTELEISYFLLRRLLGVRTEGDKKAAKVQKLSKNEVLMVNIGSLSTGGRVSAVKADLGKIVLTNPVCTEVGEKIALSRRVEKHWRLIGWGQIRRGVTIKPTVDDD", "length": 470, "header": "tr|A0A8V0XF84-1|F1NPF0_CHICK Computationally mapped isoform of protein-synthesizing GTPase OS=Gallus gallus OX=9031 GN=EIF2S3 PE=1 SV=1 CANONICAL=F1NPF0-1" }, "locus": { "chromosome": "1", "start_pos": 118347563, "end_pos": 118334933, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010007175.1", "url": "https://www.ensembl.org/id/ENSGALT00010007175.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010004322.1", "url": "https://www.ensembl.org/id/ENSGALP00010004322.1" } ] } }, { "isoform_ac": "A0A8V0XHZ8-1", "url": "https://www.uniprot.org/uniprotkb/F1NPF0/entry#A0A8V0XHZ8-1", "sequence": { "sequence": "MDVTKLTPLSPEVISRQATINIGTIGHVAHGKSTVVKAISGVHTVRFKNELERNITIKLGYANAKIYKLDDPSCSRPECYRSCGSSTPDEFPTDIPGTKGNFKLVRHVSFVDCPGHDILMATMLNGAAVMDAALLLIAGNESCPQPQTSEHLAAIEIMKLKHILILQNKIDLVKESQAKEQYEQILAFVQGTVAEGAPIIPISAQLKYNIEVVCEYIVKKIPVPLRDFTSEPRLIVIRSFDVNKPGCEVDDLKGGVAGGSILKGVLKVGQEIEVRPGIVSKDSEGKLMCKPIFSKIVSLFAEHNDLQYAAPGGLIGVGTKIDPTLCRADRMVGQVLGAVGALPEIFTELEISYFLLRRLLGVRTEGDKKAAKVQKLSKNEVLMVNIGSLSTGGRVSAVKADLGKIVLTNPVCTEVGEKIALSRRVEKHWRLIGWGQIRRGVTIKPTVDDD", "length": 450, "header": "tr|A0A8V0XHZ8-1|F1NPF0_CHICK Computationally mapped isoform of protein-synthesizing GTPase OS=Gallus gallus OX=9031 GN=EIF2S3 PE=1 SV=1 CANONICAL=F1NPF0-1" }, "locus": { "chromosome": "1", "start_pos": 118345796, "end_pos": 118334933, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010007164.1", "url": "https://www.ensembl.org/id/ENSGALT00010007164.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010004318.1", "url": "https://www.ensembl.org/id/ENSGALP00010004318.1" } ] } }, { "isoform_ac": "F1NPF0-1", "url": "https://www.uniprot.org/uniprotkb/F1NPF0/entry#F1NPF0-1", "sequence": { "sequence": "MAGDEAGVTLGQPHLSRQDLATLDVTKLTPLSPEVISRQATINIGTIGHVAHGKSTVVKAISGVHTVRFKNELERNITIKLGYANAKIYKLDDPSCSRPECYRSCGSSTPDEFPTDIPGTKGNFKLVRHVSFVDCPGHDILMATMLNGAAVMDAALLLIAGNESCPQPQTSEHLAAIEIMKLKHILILQNKIDLVKESQAKEQYEQILAFVQGTVAEGAPIIPISAQLKYNIEVVCEYIVKKIPVPLRDFTSEPRLIVIRSFDVNKPGCEVDDLKGGVAGGSILKGVLKVGQEIEVRPGIVSKDSEGKLMCKPIFSKIVSLFAEHNDLQYAAPGGLIGVGTKIDPTLCRADRMVGQVLGAVGALPEIFTELEISYFLLRRLLGVRTEGDKKAAKVQKLSKNEVLMVNIGSLSTGGRVSAVKADLGKIVLTNPVCTEVGEKIALSRRVEKHWRLIGWGQIRRGVTIKPTVDDD", "length": 472, "header": "tr|F1NPF0-1|F1NPF0_CHICK Isoform 1 of protein-synthesizing GTPase OS=Gallus gallus OX=9031 GN=EIF2S3 PE=1 SV=1 CANONICAL=F1NPF0-1" }, "locus": { "chromosome": "1", "start_pos": 118347563, "end_pos": 118334933, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010007168.1", "url": "https://www.ensembl.org/id/ENSGALT00010007168.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010004320.1", "url": "https://www.ensembl.org/id/ENSGALP00010004320.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "gga:418597", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418597", "resource": "KEGG Pathway" }, { "id": "R-GGA-381042", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-381042", "resource": "Reactome", "description": "PERK regulates gene expression" }, { "id": "R-GGA-72649", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-72649", "resource": "Reactome", "description": "Translation initiation complex formation" }, { "id": "R-GGA-72695", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-72695", "resource": "Reactome", "description": "Formation of the ternary complex, and subsequently, the 43S complex" }, { "id": "R-GGA-72702", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-72702", "resource": "Reactome", "description": "Ribosomal scanning and start codon recognition" }, { "id": "R-GGA-72731", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-72731", "resource": "Reactome", "description": "Recycling of eIF2:GDP" }, { "id": "R-GGA-9840373", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9840373", "resource": "Reactome", "description": "Cellular response to mitochondrial stress" } ], "orthologs": [ { "uniprot_canonical_ac": "F1QGW6-1", "protein_name": "Eukaryotic translation initiation factor 2 subunit 3", "gene_name": "eif2s3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAGDESGTTLGQPHLYKQDLSTLDVSKLTPLSQEIISRQATINIGTIGHVAHGKSTVVKAISGVHTVRFKNELERNITIKLGYANAKVYKLDDPSCPRPECYRSCGSSTPDEFPTDIPGTKGNFKLVRHVSFVDCPGHDILMATMLNGAAVMDAALLLIAGNESCPQPQTSEHLAAIEIMKLKHILILQNKIDLVKESQAKEQYEQILAFVQGTVAEGAPIIPISAQLKYNIEVVCEYIVNKIPVPVRDFTSEPRLIVIRSFDVNKPGCEVDDLKGGVAGGSILKGVLKVGQELEVRPGIVSKDHEGKLMCKPIFSKIVSLFAEHNDLQYAAPGGLIGVGTKIDPTLCRADRMVGQVLGAVGALPEIFTELEISYFLLRRLLGVRTEGDKKAAKVQKLSKNEVLMVNIGSLSTGGRVSAVKADLAKIVLTNPVCTEVGEKIALSRRVEKHWRLIGWGQIRRGVTITPTVDDD", "length": 472 }, "evidence": [ { "id": "F1NPF0", "url": "https://omabrowser.org/oma/group/F1NPF0/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "G3HQ45-1", "protein_name": "protein-synthesizing GTPase", "gene_name": "Eif2s3", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAGGEVGVTLGQPHLSRQDLATLDVTKLTPLSHEVISRQATINIGTIGHVAHGKSTVVKAISGVHTVRFKNELERNITIKLGYANAKIYKLDDPSCPRPECYRSCGSSTPDEFPTDIPGTKGNFKLVRHVSFVDCPGHDILMATMLNGAAVMDAALLLIAGNESCPQPQTSEHLAAIEIMKLKHILILQNKIDLVKESQAKEQYEQILAFVQGTVAEGAPIIPISAQLKYNIEVVCEYIVKKIPVPPRDFTSEPRLIVIRSFDVNKPGCEVDDLKGGVAGGSILKGVLKVGQEIEVRPGIVSKDSEGKLMCKPIFSKIVSLFAEHNDLQYAAPGGLIGVGTKIDPTLCRADRMVGQVLGAVGALPEIFTELEISYFLLRRLLGVRTEGDKKAAKVQKLSKNEVLMVNIGSLSTGGRVSAVKADLGKIVLTNPVCTEVGEKIALSRRVEKHWRLIGWGQIRRGVTIKPTVDDD", "length": 472 }, "evidence": [ { "id": "F1NPF0", "url": "https://omabrowser.org/oma/group/F1NPF0/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "O64490-1", "protein_name": "protein-synthesizing GTPase", "gene_name": "EIF2", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSRNKGLAEQDLKKLDVTVLHPLSPEVISRQATINIGTIGHVAHGKSTVVKAISGVQTVRFKNELERNITIKLGYANAKIYKCEDEKCPRPMCYKAYGSGKEDTPNCDVPGFENSKMKLLRHVSFVDCPGHDILMATMLNGAAIMDGALLLIAANETCPQPQTSEHLAAVEIMQLKHIIILQNKIDLIQENVAINQHEAIQKFIMNTVADAAPIVPVSAQLKYNIDVVCEYIVKKIPIPERNFVSPPNMIVIRSFDVNKPGYEVDEIKGGVAGGSILRGVLRVNQLIEIRPGIVTKDERGNSKCTPIYSRIISLYAEQNELQFAVPGGLIGVGTTMDPTLTRADRLVGQVLGEIGSLPDVFVELEVNFFLLRRLLGVRTKGSEKQGKVSKLTKGEILMLNIGSMSTGAKVVGVKVDLAKLQLTAPVCTSKGEKVALSRRVEKHWRLIGWGQIQAGTTIEVPPSPF", "length": 465 }, "evidence": [ { "id": "F1NPF0", "url": "https://omabrowser.org/oma/group/F1NPF0/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "P20461-1", "protein_name": "Eukaryotic translation initiation factor 2 subunit 3", "gene_name": "EIF2S3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAGGEAGVTLGQPHLSRQDLATLDVTKLTPLSHEVISRQATINIGTIGHVAHGKSTVVKAISGVHTVRFKNELERNITIKLGYANAKIYKLDDPSCPRPECYRSCGSSTPDEFPTDIPGTKGNFKLVRHVSFVDCPGHDILMATMLNGAAVMDAALLLIAGNESCPQPQTSEHLAAIEIMKLKHILILQNKIDLVKESQAKEQYDQILAFVQGTVAEGAPIIPISAQLKYNIEVVCEYIVKKIPVPPRDFTSEPRLIVIRSFDVNKPGCEVDDLKGGVAGGSILKGVLKVGQEIEVRPGIVSKDSEGKLMCKPIFSKIVSLFAEHNDLQYAAPGGLIGVGTKIDPTLCRADRMVGQVLGAVGALPEIFTELEISYFLLRRLLGVRTEGDKKAAKVQKLSKNEVLMVNIGSLSTGGRVSAVKADLGKIVLTNPVCTEVGEKIALSRRVEKHWRLIGWGQIRRGVTIKPTVDDD", "length": 472 }, "evidence": [ { "id": "F1NPF0", "url": "https://omabrowser.org/oma/group/F1NPF0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P32481-1", "protein_name": "Eukaryotic translation initiation factor 2 subunit gamma", "gene_name": "GCD11", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSDLQDQEPSIIINGNLEPVGEPDIVEETEVVAQETQETQDADKPKKKVAFTGLEEDGETEEEKRKREFEEGGGLPEQPLNPDFSKLNPLSAEIINRQATINIGTIGHVAHGKSTVVRAISGVQTVRFKDELERNITIKLGYANAKIYKCQEPTCPEPDCYRSFKSDKEISPKCQRPGCPGRYKLVRHVSFVDCPGHDILMSTMLSGAAVMDAALLLIAGNESCPQPQTSEHLAAIEIMKLKHVIILQNKVDLMREESALEHQKSILKFIRGTIADGAPIVPISAQLKYNIDAVNEFIVKTIPVPPRDFMISPRLIVIRSFDVNKPGAEIEDLKGGVAGGSILNGVFKLGDEIEIRPGIVTKDDKGKIQCKPIFSNIVSLFAEQNDLKFAVPGGLIGVGTKVDPTLCRADRLVGQVVGAKGHLPNIYTDIEINYFLLRRLLGVKTDGQKQAKVRKLEPNEVLMVNIGSTATGARVVAVKADMARLQLTSPACTEINEKIALSRRIEKHWRLIGWATIKKGTTLEPIA", "length": 527 }, "evidence": [ { "id": "F1NPF0", "url": "https://omabrowser.org/oma/group/F1NPF0/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P41091-1", "protein_name": "Eukaryotic translation initiation factor 2 subunit 3", "gene_name": "EIF2S3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAGGEAGVTLGQPHLSRQDLTTLDVTKLTPLSHEVISRQATINIGTIGHVAHGKSTVVKAISGVHTVRFKNELERNITIKLGYANAKIYKLDDPSCPRPECYRSCGSSTPDEFPTDIPGTKGNFKLVRHVSFVDCPGHDILMATMLNGAAVMDAALLLIAGNESCPQPQTSEHLAAIEIMKLKHILILQNKIDLVKESQAKEQYEQILAFVQGTVAEGAPIIPISAQLKYNIEVVCEYIVKKIPVPPRDFTSEPRLIVIRSFDVNKPGCEVDDLKGGVAGGSILKGVLKVGQEIEVRPGIVSKDSEGKLMCKPIFSKIVSLFAEHNDLQYAAPGGLIGVGTKIDPTLCRADRMVGQVLGAVGALPEIFTELEISYFLLRRLLGVRTEGDKKAAKVQKLSKNEVLMVNIGSLSTGGRVSAVKADLGKIVLTNPVCTEVGEKIALSRRVEKHWRLIGWGQIRRGVTIKPTVDDD", "length": 472 }, "evidence": [ { "id": "F1NPF0", "url": "https://omabrowser.org/oma/group/F1NPF0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P81795-1", "protein_name": "Eukaryotic translation initiation factor 2 subunit 3, X-linked", "gene_name": "Eif2s3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAGGEAGVTLGQPHLSRQDLATLDVTKLTPLSHEVISRQATINIGTIGHVAHGKSTVVKAISGVHTVRFKNELERNITIKLGYANAKIYKLDDPSCPRPECYRSCGSSTPDEFPTDIPGTKGNFKLVRHVSFVDCPGHDILMATMLNGAAVMDAALLLIAGNESCPQPQTSEHLAAIEIMKLKHILILQNKIDLVKESQAKEQYEQILAFVQGTVAEGAPIIPISAQLKYNIEVVCEYIVKKIPVPPRDFTSEPRLIVIRSFDVNKPGCEVDDLKGGVAGGSILKGVLKVGQEIEVRPGIVSKDSEGKLMCKPIFSKIVSLFAEHNDLQYAAPGGLIGVGTKIDPTLCRADRMVGQVLGAVGALPEIFTELEISYFLLRRLLGVRTEGDKKAAKVQKLSKNEVLMVNIGSLSTGGRVSAVKADLGKIVLTNPVCTEVGEKIALSRRVEKHWRLIGWGQIRRGVTIKPTVDDD", "length": 472 }, "evidence": [ { "id": "F1NPF0", "url": "https://omabrowser.org/oma/group/F1NPF0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q24208-1", "protein_name": "Eukaryotic translation initiation factor 2 subunit 3", "gene_name": "eIF2gamma", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MATAEAQIGVNRNLQKQDLSNLDVSKLTPLSPEVISRQATINIGTIGHVAHGKSTVVKAISGVQTVRFKNELERNITIKLGYANAKIYKCDNPKCPRPASFVSDASSKDDSLPCTRLNCSGNFRLVRHVSFVDCPGHDILMATMLNGAAVMDAALLLIAGNESCPQPQTSEHLAAIEIMKLKQILILQNKIDLIKESQAKEQYEEITKFVQGTVAEGAPIIPISAQLKYNIDVLCEYIVNKIPVPPRDFNAPPRLIVIRSFDVNKPGCEVADLKGGVAGGSILSGVLKVGQEIEVRPGVVTKDSDGNITCRPIFSRIVSLFAEQNELQYAVPGGLIGVGTKIDPTLCRADRLVGQVLGAVGQLPDIYQELEISYYLLRRLLGVRTDGDKKGARVEKLQKNEILLVNIGSLSTGGRISATKGDLAKIVLTTPVCTEKGEKIALSRRVENHWRLIGWGQIFGGKTITPVLDSQVAKK", "length": 475 }, "evidence": [ { "id": "F1NPF0", "url": "https://omabrowser.org/oma/group/F1NPF0/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q2KHU8-1", "protein_name": "Eukaryotic translation initiation factor 2 subunit 3", "gene_name": "EIF2S3", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAGGEAGVTLGQPHLSRQDLATLDVSKLTPLSHEVISRQATINIGTIGHVAHGKSTVVKAISGVHTVRFKNELERNITIKLGYANAKIYKLDDPSCPRPECYRSCGSSTPDEFPTDIPGTKGNFKLVRHVSFVDCPGHDILMATMLNGAAVMDAALLLIAGNESCPQPQTSEHLAAIEIMKLKHILILQNKIDLVKESQAKEQYEQILAFVQGTVAEGAPIIPISAQLKYNIEVVCEYIVKKIPVPPRDFTSEPRLIVIRSFDVNKPGCEVDDLKGGVAGGSILKGVLKVGQEIEVRPGIVSKDSEGKLMCKPIFSKIVSLFAEHNDLQYAAPGGLIGVGTKIDPTLCRADRMVGQVLGAVGALPEIFTELEISYFLLRRLLGVRTEGDKKAAKVQKLSKNEVLMVNIGSLSTGGRVSAVKADLGKIVLTNPVCTEVGEKIALSRRVEKHWRLIGWGQIRRGVTIKPTVDDD", "length": 472 }, "evidence": [ { "id": "F1NPF0", "url": "https://omabrowser.org/oma/group/F1NPF0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q54XD8-1", "protein_name": "Eukaryotic translation initiation factor 2 subunit 3", "gene_name": "eif2s3", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MATKNKPNLSVQDVKLLNVNELTPLTPNVISRQATINIGTIGHVAHGKSTVVKAISGVLTVRFTSEFKRNITIKLGYANAKIYKCDNPQCERPGCYKSARSNTEDNPQCERPGCGGRMTLLRHVSFVDCPGHDVLMATMLNGAAVMDAALLLIAGNESCPQPQTSEHIAAIEIMNLKNIIILQNKIDLVKEAAAQEQYGQILKFIQGTIAENAPIIPISAQMKYNIDVICEYIVKKIPIPVRDFTSDPRMIVIRSFDVNKPGSRVDEIKGGVAGGSILKGVLKIGDEIEVRPGVISKELDGKIKCSPIFCRIISLFAEENELQYAVPGGLIGVGTKIDPTLCRADRLVGQVLGSVGKLPEIFVALEVNFFLLRRLLGVKSDGDKQSKVKKLSKEDTLMVNIGSTSTGCRVVAVKHDLAKLQLLTPVCSQEGEKIALSRRVDKNWRLIGWGEIKKGTVLTN", "length": 460 }, "evidence": [ { "id": "F1NPF0", "url": "https://omabrowser.org/oma/group/F1NPF0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q9Z0N1-1", "protein_name": "Eukaryotic translation initiation factor 2 subunit 3, X-linked", "gene_name": "Eif2s3x", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAGGEGGVTLGQPHLSRQDLATLDVTKLTPLSHEVISRQATINIGTIGHVAHGKSTVVKAISGVHTVRFKNELERNITIKLGYANAKIYKLDDPSCPRPECYRSCGSSTPDEFPTDIPGTKGNFKLVRHVSFVDCPGHDILMATMLNGAAVMDAALLLIAGNESCPQPQTSEHLAAIEIMKLKHILILQNKIDLVKESQAKEQYEQILAFVQGTVAEGAPIIPISAQLKYNIEVVCEYIVKKIPVPPRDFTSEPRLIVIRSFDVNKPGCEVDDLKGGVAGGSILKGVLKVGQEIEVRPGIVSKDSEGKLMCKPIFSKIVSLFAEHNDLQYAAPGGLIGVGTKIDPTLCRADRMVGQVLGAVGALPEIFTELEISYFLLRRLLGVRTEGDKKAAKVQKLSKNEVLMVNIGSLSTGGRVSAVKADLGKIVLTNPVCTEVGEKIALSRRVEKHWRLIGWGQIRRGVTIKPTVDDD", "length": 472 }, "evidence": [ { "id": "F1NPF0", "url": "https://omabrowser.org/oma/group/F1NPF0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "GTPase activity", "id": "GO:0003924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003924", "evidence": [ { "database": "UniProtKB", "id": "F1NPF0", "url": "https://www.uniprot.org/uniprotkb/F1NPF0" } ], "pmid": "" }, { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "F1NPF0", "url": "https://www.uniprot.org/uniprotkb/F1NPF0" } ], "pmid": "" }, { "name": "tRNA binding", "id": "GO:0000049", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000049", "evidence": [ { "database": "UniProtKB", "id": "F1NPF0", "url": "https://www.uniprot.org/uniprotkb/F1NPF0" } ], "pmid": "" }, { "name": "translation initiation factor activity", "id": "GO:0003743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003743", "evidence": [ { "database": "UniProtKB", "id": "F1NPF0", "url": "https://www.uniprot.org/uniprotkb/F1NPF0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "formation of translation preinitiation complex", "id": "GO:0001731", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001731", "evidence": [ { "database": "UniProtKB", "id": "F1NPF0", "url": "https://www.uniprot.org/uniprotkb/F1NPF0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "eukaryotic translation initiation factor 2 complex", "id": "GO:0005850", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005850", "evidence": [ { "database": "UniProtKB", "id": "F1NPF0", "url": "https://www.uniprot.org/uniprotkb/F1NPF0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 162, "end_pos": 164, "annotation": "n_glycosylation_sequon" }, { "start_pos": 76, "end_pos": 78, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "19669", "name": "", "equation": "GTP + H2O = GDP + phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YVX9-1", "F1NSA8-1", "R4GJA4-1", "A0A1L1RKZ0-1", "E1BUS1-1", "Q5ZHW4-1", "Q90694-1", "P08070-1", "P09642-1", "P09643-1", "P09644-1", "P09645-1", "Q5F352-1", "Q5ZMS3-1", "Q90705-1", "Q90835-1", "Q90965-1", "Q98932-1", "A0A3Q2UHM4-1", "Q5ZHX1-1", "A0A1D5PT95-1", "E1BQI2-1", "F1NPF0-1", "A0A8V0XVU5-1", "A0A8V0XBX5-1", "A0A8V0Z564-1", "A0A8V0Y9R6-1", "A0A1D5PM27-1", "A0A8V0Z8U4-1", "A0A8V0ZJW2-1", "A0A8V1ABB1-1", "A0A8V0YDX6-1", "E1BWN3-1", "Q5F499-1", "Q5ZKU5-1", "P02552-1", "P08642-1", "P26990-1", "P42558-1", "Q5F470-1", "Q5ZIT5-1", "Q5ZJN2-1", "P50146-1", "A0A8V0ZNW3-1", "A0A8V0YIM0-1", "A0A8V0ZRZ2-1", "A0A8V1A9Z8-1", "Q1KME6-1", "Q5ZLG1-1", "P84172-1", "A0A8V1ACG4-1", "A0A8V0YTL7-1", "A0A3Q2UG55-1", "A0A8V1AIF5-1", "Q5ZHV1-1", "A0A8V0Z5P2-1", "A0A8V0Y4A4-1", "A0A8V0YA62-1", "A0A8V0YVM3-1", "A0A1D5P1F5-1", "A0A8V1ADZ7-1", "F1NWF1-1", "A0A8V1AP30-1", "A0A8V0XDD5-1", "A0A8V0XMC5-1", "A0A8V0YWW1-1", "A0A8V0ZR14-1", "A0A8V0Y2H3-1", "Q5ZJD3-1", "Q5ZM73-1", "Q5ZM83-1", "A0A8V0YTY9-1", "A0A8V0ZXW3-1", "A0A8V1AHB3-1", "A0A8V0YDI7-1", "A0A1D5NV13-1", "A0A8V0XGK7-1", "A0A8V0YHK2-1", "A0A8V0XC33-1", "A0A8V0XKC3-1", "F1P278-1", "A0A8V0ZG00-1", "A0A8V1AGP3-1", "A0A8V1AN75-1", "A0A8V0Z416-1", "A0A8V1A0V4-1", "A0A8V1A8Q7-1", "A0A8V1ABD3-1", "A0A8V1API8-1", "A0A8V0YIU8-1", "A0A8V0X962-1", "A0A8V1AKH3-1", "P79784-1", "A0A1D5P533-1", "A0A8V1A8I5-1", "A0A8V1AE09-1", "Q9PSX7-1", "Q5ZKR4-1", "A0A8V0YGN8-1", "A0A8V0XNL0-1", "A0A8V0Y3H2-1" ], "evidence": [ { "id": "19669", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/19669" } ] }, { "id": "R-GGA-156808", "name": "Formation of translation initiation complexes yielding circularized Ceruloplasmin mRNA in a 'closed-loop' conformation", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [ "R-GGA-156803" ], "output_participant_list": [], "enzyme_list": [ "F1NPF0-1", "F1NPA9-1", "A0A8V0YUW3-1" ], "evidence": [ { "id": "R-GGA-156808", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-156808" } ] }, { "id": "R-GGA-157849", "name": "Formation of translation initiation complexes containing mRNA that does not circularize", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1NPF0-1", "F1NPA9-1", "A0A8V0YUW3-1" ], "evidence": [ { "id": "R-GGA-157849", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-157849" } ] }, { "id": "R-GGA-381111", "name": "EIF2AK3 (PERK) phosphorylates EIF2S1 (eIF2-alpha)Phosphorylation of eIF2-alpha by PERK", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, endoplasmic reticulum membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1NPF0-1", "E1BX69-1" ], "evidence": [ { "id": "R-GGA-381111", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-381111" } ] }, { "id": "R-GGA-72621", "name": "Ribosomal scanning", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1NPF0-1", "F1NPA9-1", "A0A8V0YUW3-1" ], "evidence": [ { "id": "R-GGA-72621", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-72621" } ] }, { "id": "R-GGA-72663", "name": "De novo formation of eIF2:GTP", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1NPF0-1" ], "evidence": [ { "id": "R-GGA-72663", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-72663" } ] }, { "id": "R-GGA-72669", "name": "Met-tRNAi binds to eIF2:GTP to form the ternary complex", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1NPF0-1" ], "evidence": [ { "id": "R-GGA-72669", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-72669" } ] }, { "id": "R-GGA-72670", "name": "Formation of eIF2:GDP:eIF2B intermediate", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1NPF0-1" ], "evidence": [ { "id": "R-GGA-72670", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-72670" } ] }, { "id": "R-GGA-72691", "name": "Formation of the 43S pre-initiation complex", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1NPF0-1", "F1NPA9-1" ], "evidence": [ { "id": "R-GGA-72691", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-72691" } ] }, { "id": "R-GGA-72697", "name": "Start codon recognition", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [ "R-ALL-72617", "R-GGA-72616", "R-GGA-72557" ], "output_participant_list": [], "enzyme_list": [ "F1NPF0-1", "F1NPA9-1", "A0A8V0YUW3-1" ], "evidence": [ { "id": "R-GGA-72697", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-72697" } ] }, { "id": "R-GGA-72722", "name": "eIF2 activation", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1NPF0-1" ], "evidence": [ { "id": "R-GGA-72722", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-72722" } ] }, { "id": "R-GGA-9840415", "name": "DELE1(143-515):EIF2AK1 enhances phosphorylation of EIF2S1 (EIF2alpha)", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1NPF0-1", "A0A8V0ZKA2-1" ], "evidence": [ { "id": "R-GGA-9840415", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9840415" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-72617", "participant_name": "eIF1 [cytosol]", "crossref": [ { "id": "36080", "database": "ChEBI", "url": "" } ] }, { "participant_id": "R-GGA-156803", "participant_name": "PABPC1 [cytosol]", "crossref": [ { "id": "A0A8V0YD15", "database": "UniProt", "url": "" }, { "id": "ENSGALG00010011414", "database": "ENSEMBL", "url": "" }, { "id": "ENSGALP00010015549", "database": "ENSEMBL", "url": "" }, { "id": "ENSGALT00010027294", "database": "ENSEMBL", "url": "" } ] }, { "participant_id": "R-GGA-72557", "participant_name": "EIF1AX [cytosol]", "crossref": [ { "id": "A0A8V0XB11", "database": "UniProt", "url": "" }, { "id": "ENSGALG00010002653", "database": "ENSEMBL", "url": "" }, { "id": "ENSGALP00010003837", "database": "ENSEMBL", "url": "" }, { "id": "ENSGALT00010006153", "database": "ENSEMBL", "url": "" } ] }, { "participant_id": "R-GGA-72616", "participant_name": "EIF5 [cytosol]", "crossref": [ { "id": "Q5ZIE0", "database": "UniProt", "url": "" }, { "id": "ENSGALG00010015759", "database": "ENSEMBL", "url": "" }, { "id": "ENSGALP00010021894", "database": "ENSEMBL", "url": "" }, { "id": "ENSGALT00010037941", "database": "ENSEMBL", "url": "" }, { "id": "XP_046797792.1", "database": "RefSeq", "url": "" }, { "id": "XP_015142965.1", "database": "RefSeq", "url": "" }, { "id": "XP_046774661.1", "database": "RefSeq", "url": "" }, { "id": "XP_046774662.1", "database": "RefSeq", "url": "" }, { "id": "XP_046774664.1", "database": "RefSeq", "url": "" }, { "id": "XP_046774660.1", "database": "RefSeq", "url": "" }, { "id": "XP_046774663.1", "database": "RefSeq", "url": "" }, { "id": "XP_046797793.1", "database": "RefSeq", "url": "" }, { "id": "NP_001006488.1", "database": "RefSeq", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A0A1D5NV13", "gene_name": "RIT2", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5NV13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NV13" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A1D5NV13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NV13" } ] } ] }, { "uniprot_ac": "A0A1D5P1F5", "gene_name": "RAB40C", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5P1F5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P1F5" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A1D5P1F5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P1F5" } ] } ] }, { "uniprot_ac": "A0A1D5P533", "gene_name": "RASEF", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5P533", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P533" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A1D5P533", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P533" } ] } ] }, { "uniprot_ac": "A0A1D5PM27", "gene_name": "OPA1", "activity": [ { "ec_number": "3.6.5.5", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5PM27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PM27" } ] }, { "ec_number": "3.6.5.5", "activity": "", "evidence": [ { "id": "A0A1D5PM27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PM27" } ] } ] }, { "uniprot_ac": "A0A1D5PT95", "gene_name": "KRAS", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + 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This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015130457", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015130457" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1P0M3", "url": "https://www.uniprot.org/uniprotkb/F1P0M3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TMTC4", "url": "https://www.uniprot.org/uniprotkb/F1P0M3", "locus": { "chromosome": "1", "start_pos": 143965727, "end_pos": 143907857, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010005236", "url": "https://www.ensembl.org/id/ENSGALG00010005236" } ] } } ], "crossref": [ { "id": "F1P0M3", "url": "https://alphafold.ebi.ac.uk/entry/F1P0M3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000016870", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000016870", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "418772", "url": "https://www.ncbi.nlm.nih.gov/gene/418772", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011990", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011990", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013618", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013618", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019734", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019734", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:418772", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418772", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HWQHAVA", "url": "https://omabrowser.org/oma/group/HWQHAVA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XFN4", "url": "https://www.orthodb.org/?gene=A0A8V0XFN4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XMA6", "url": "https://www.orthodb.org/?gene=A0A8V0XMA6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XQ22", "url": "https://www.orthodb.org/?gene=A0A8V0XQ22", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1P0M3", "url": "https://www.orthodb.org/?gene=F1P0M3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR44227", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR44227", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR44227:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR44227:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF08409", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08409", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13181", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13181", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13432", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13432", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14559", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14559", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015130457", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015130457", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0XFN4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XFN4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XFN4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XFN4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XMA6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMA6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XMA6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMA6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XQ22", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ22", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XQ22-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ22-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1P0M3", "url": "https://www.uniprot.org/uniprotkb/F1P0M3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1P0M3-1", "url": "https://www.uniprot.org/uniprotkb/F1P0M3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAQTEPNLDHDISWFLLPSCWAKTVVALISFLCFANSYDGDFVFDDSEAIINNKDLRAETPLGDLWHHDFWGSKLSSNTSHKSYRPLTVLTFRINYLFAGGFYPVGFHVINIILHCTISVLMVDVFSILLGGLQFTNKGRRLNLAPKTSLLAALLFAVHPVHTECVAGIVGRADLLCALFFLLSFLGYCKAFRENKEGHNFSVFWVLVSVLLGAIAMLCKEQGITVLGLNAVFDALVINKLNILEIIQKLLRKDKLLESAGLLRKGLLFRITLLMSGGASILYIRWRIMGTGPPAFTEVDNPASFADSLFVRAINYNYYYSLNAWLLLCPWWLCFDWSMGCIPLIKSVSDWRIIALAALWFCLIGLICQALCSEDSYKRRILTLGLGFLIIPFLPASNLFFRVGFVVAERVIYLPSIGYIILFTYGFSLLSKQAKKKKILAVAVLGILLMNIMRCALRSSQWRSEEQLFRSALSVCPLNAKVHYNVGKNLADKGNQSAAIKYYREAVRLNPKYVHAMNNLGNILKERNELQEAEELLSLAVQIQPDFAAAWMNLGIVQNSLRRFEEAEQSYWTAIKHRKKYPDCYYNLGRLYADLNRHIDALNAWRNATVLKPEHSLAWNNMIILLDNTGNLAQAEAVGREALELIPNDHSLMFSLANVLGKSQKYKESEALFLKAIKANPNAASYHGNLAVLYHRWGNLDLAKKHYEVSLKLDPMAPGTKENYNLLRRKLEQLQKKGGA", "length": 740, "header": "tr|F1P0M3-1|F1P0M3_CHICK Isoform 1 of dolichyl-phosphate-mannose--protein mannosyltransferase OS=Gallus gallus OX=9031 GN=TMTC4 PE=3 SV=2 CANONICAL=F1P0M3-1" }, "isoforms": [ { "isoform_ac": "A0A8V0XFN4-1", "url": "https://www.uniprot.org/uniprotkb/F1P0M3/entry#A0A8V0XFN4-1", "sequence": { "sequence": "MAQTEPNLDHDISWFLLPSCWAKTVVALISFLCFANSYDGDFVFDDSEAIINNKDLRAETPLGDLWHHDFWGSKLSSNTSHKSYRPLTVLTFRINYLFAGGFYPVGFHVINIILHCTISVLMVDVFSILLGGLQFTNKGRRLNLAPKTSLLAALLFAVHPVHTECVAGIVGRADLLCALFFLLSFLGYCKAFRENKEGHNFSVFWVLVSVLLGAIAMLCKEQGITVLGLNAVFDALVINKLNILEIIQKLLRKDKLLESAGLLRKGLLFRITLLMSGGASILYIRWRIMGTGPPAFTEVDNPASFADSLFVRAINYNYYYSLNAWLLLCPWWLCFDWSMGCIPLIKSVSDWRIIALAALWFCLIGLICQALCSEDSYKRRILTLGLGFLIIPFLPASNLFFRVGFVVAERVIYLPSIGYIILFTYGFSLLSKQAKKKKILAVAVLGILLMNIMRCALRSSQWRSEEQLFRSALSVCPLNAKVHYNVGKNLADKGNQSAAIKYYREAVRLNPKYVHAMNNLGNILKERNELQEAEELLSLAVQIQPDFAAAWMNLGIVQNSLRRFEEAEQSYWTAIKHRKKYPDCYYNLGRLYADLNRHIDALNAWRNATVLKPEHSLAWNNMIILLDNTGNLAQAEAVGREALELIPNDHSLMFSLANVLGKSQKYKKLSKMKILKIL", "length": 678, "header": "tr|A0A8V0XFN4-1|F1P0M3_CHICK Computationally mapped isoform of dolichyl-phosphate-mannose--protein mannosyltransferase OS=Gallus gallus OX=9031 GN=TMTC4 PE=3 SV=1 CANONICAL=F1P0M3-1" }, "locus": { "chromosome": "1", "start_pos": 143954146, "end_pos": 143909621, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010012387.1", "url": "https://www.ensembl.org/id/ENSGALT00010012387.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010006951.1", "url": "https://www.ensembl.org/id/ENSGALP00010006951.1" } ] } }, { "isoform_ac": "A0A8V0XMA6-1", "url": "https://www.uniprot.org/uniprotkb/F1P0M3/entry#A0A8V0XMA6-1", "sequence": { "sequence": "MAQTEPNLDHDISWFLLPSCWAKTVVALISFLCFANSYDGDFVFDDSEAIINNKVAGIVGRADLLCALFFLLSFLGYCKAFRENKEGHNFSVFWVLVSVLLGAIAMLCKEQGITVLGLNAVFDALVINKLNILEIIQKLLRKDKLLESAGLLRKGLLFRITLLMSGGASILYIRWRIMGTGPPAFTEVDNPASFADSLFVRAINYNYYYSLNAWLLLCPWWLCFDWSMGCIPLIKSVSDWRIIALAALWFCLIGLICQALCSEDSYKRRILTLGLGFLIIPFLPASNLFFRVGFVVAERVIYLPSIGYIILFTYGFSLLSKQAKKKKILAVAVLGILLMNIMRCALRSSQWRSEEQLFRSALSVCPLNAKVHYNVGKNLADKGNQSAAIKYYREAVRLNPKYVHAMNNLGNILKERNELQEAEELLSLAVQIQPDFAAAWMNLGIVQNSLRRFEEAEQSYWTAIKHRKKYPDCYYNLGRLYADLNRHIDALNAWRNATVLKPEHSLAWNNMIILLDNTGNLAQAEAVGREALELIPNDHSLMFSLANVLGKSQKYKESEALFLKAIKANPNAASYHGNLAVLYHRWGNLDLAKKHYEVSLKLDPMAPGTKENYNLLRRKLEQLQKKGGA", "length": 629, "header": "tr|A0A8V0XMA6-1|F1P0M3_CHICK Computationally mapped isoform of dolichyl-phosphate-mannose--protein mannosyltransferase OS=Gallus gallus OX=9031 GN=TMTC4 PE=3 SV=1 CANONICAL=F1P0M3-1" }, "locus": { "chromosome": "1", "start_pos": 143960953, "end_pos": 143909621, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010012389.1", "url": "https://www.ensembl.org/id/ENSGALT00010012389.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010006953.1", "url": "https://www.ensembl.org/id/ENSGALP00010006953.1" } ] } }, { "isoform_ac": "A0A8V0XQ22-1", "url": "https://www.uniprot.org/uniprotkb/F1P0M3/entry#A0A8V0XQ22-1", "sequence": { "sequence": "MAQTEPNLDHDISWFLLPSCWAKTVVALISFLCFANSYDGDFVFDDSEAIINNKDLRAETPLGDLWHHDFWGSKLSSNTSHKSYRPLTVLTFRINYLFAGGFYPVGFHVINIILHCTISVLMVDVFSILLGGLQFTNKGRRLNLAPKTSLLAALLFAVHPVHTECVAGIVGRADLLCALFFLLSFLGYCKAFRENKEGHNFSVFWVLVSVLLGAIAMLCKEQGITVLGLNAVFDALVINKLNILEIIQKLLRKDKLLESAGLLRKGLLFRITLLMSGGASILYIRWRIMGTGPPAFTEVDNPASFADSLFVRAINYNYYYSLNAWLLLCPWWLCFDWSMGCIPLIKSVSDWRIIALAALWFCLIGLICQALCSEDSYKRRILTLGLGFLIIPFLPASNLFFRVGFVVAERVIYLPSIGYIILFTYGFSLLSKQAKKKKILAVAVLGILLMNIMRCALRSSQWRSEEQLFRSALSVCPLNAKVHYNVGKNLADKGNQSAAIKYYREAVRLNPKYVHAMNNLGNILKERNELQEAEELLSLAVQIQPDFAAAWMNLGIVQNSLRRFEEAEQSYWTAIKHRKKYPDCYYNLGRLYADLNRHIDALNAWRNATVLKPEHSLAWNNMIILLDNTGNLAQAEAVGREALELIPNDHSLMFSLANVLGKSQKYKESEALFLKAIKANPNAASYHGNLGENVHHKRFVSHRATEICSSGEDTPGFKTRFWQAANGKERSVR", "length": 733, "header": "tr|A0A8V0XQ22-1|F1P0M3_CHICK Computationally mapped isoform of dolichyl-phosphate-mannose--protein mannosyltransferase OS=Gallus gallus OX=9031 GN=TMTC4 PE=3 SV=1 CANONICAL=F1P0M3-1" }, "locus": { "chromosome": "1", "start_pos": 143961662, "end_pos": 143909621, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010012390.1", "url": "https://www.ensembl.org/id/ENSGALT00010012390.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010006954.1", "url": "https://www.ensembl.org/id/ENSGALP00010006954.1" } ] } }, { "isoform_ac": "F1P0M3-1", "url": "https://www.uniprot.org/uniprotkb/F1P0M3/entry#F1P0M3-1", "sequence": { "sequence": "MAQTEPNLDHDISWFLLPSCWAKTVVALISFLCFANSYDGDFVFDDSEAIINNKDLRAETPLGDLWHHDFWGSKLSSNTSHKSYRPLTVLTFRINYLFAGGFYPVGFHVINIILHCTISVLMVDVFSILLGGLQFTNKGRRLNLAPKTSLLAALLFAVHPVHTECVAGIVGRADLLCALFFLLSFLGYCKAFRENKEGHNFSVFWVLVSVLLGAIAMLCKEQGITVLGLNAVFDALVINKLNILEIIQKLLRKDKLLESAGLLRKGLLFRITLLMSGGASILYIRWRIMGTGPPAFTEVDNPASFADSLFVRAINYNYYYSLNAWLLLCPWWLCFDWSMGCIPLIKSVSDWRIIALAALWFCLIGLICQALCSEDSYKRRILTLGLGFLIIPFLPASNLFFRVGFVVAERVIYLPSIGYIILFTYGFSLLSKQAKKKKILAVAVLGILLMNIMRCALRSSQWRSEEQLFRSALSVCPLNAKVHYNVGKNLADKGNQSAAIKYYREAVRLNPKYVHAMNNLGNILKERNELQEAEELLSLAVQIQPDFAAAWMNLGIVQNSLRRFEEAEQSYWTAIKHRKKYPDCYYNLGRLYADLNRHIDALNAWRNATVLKPEHSLAWNNMIILLDNTGNLAQAEAVGREALELIPNDHSLMFSLANVLGKSQKYKESEALFLKAIKANPNAASYHGNLAVLYHRWGNLDLAKKHYEVSLKLDPMAPGTKENYNLLRRKLEQLQKKGGA", "length": 740, "header": "tr|F1P0M3-1|F1P0M3_CHICK Isoform 1 of dolichyl-phosphate-mannose--protein mannosyltransferase OS=Gallus gallus OX=9031 GN=TMTC4 PE=3 SV=2 CANONICAL=F1P0M3-1" }, "locus": { "chromosome": "1", "start_pos": 143960953, "end_pos": 143909621, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010012388.1", "url": "https://www.ensembl.org/id/ENSGALT00010012388.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010006952.1", "url": "https://www.ensembl.org/id/ENSGALP00010006952.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "gga:418772", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418772", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "B0S6W0-1", "protein_name": "dolichyl-phosphate-mannose--protein mannosyltransferase", "gene_name": "tmtc4", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MVLSEPYWDHHIPLPKLGPLHSRLTTAFVALICFINSYDGDFVFDDSEAIINNKDLNPDTPLSNIWKNDFWGSNLSSNSSHKSYRPLTVLTFRINYLLAGGLHPVGFHVLNVALHCVISVLMIDVFAILIGGPVQDGKGAKLSLPPKASFLAALFFAAHPVHTESVAGIVGRADLLCALFFQLSFLVYCKAFQVGGDKKFSVLWIFGSILLCAVAMLCKEQGITALGVNAAYDILMVCNLNIYELAHRLLSRRKSADIGGLPRNGLLMRLALLFLGGSLLMYTRWKIMGTGPPSFTEVDNPASFAENIILRIVNYNYYYSLNAWLLLCPWWLCFDWSMGCVPLISSAADWRIVWPAVLWFCLIGLVSQALFSQDSNKRRTLTFGLVLLVIPFLPASNVFFRVGFVIAERVLYLSSAGYCLILAYAVGYCSCHWRKHKRLLRAATLTLLCVNVTRSAQRSQQWRSEQSLFTSALSVCPLNAKVHYNVGKNLADRGNQSAAVQYYREAVRLHPKYVHAMNNLGNILKERNELKEAEELLSAAVHIQPDFAAAWMNLGIVQNSLKKFNKAEQSYWNAIRFRKKYPDCYYNLGRLYADLNRSIDALNAWRNATMLKPDHSLAWNNMVILLDNTGNLAQAELIGKEALKILPKDHTIMFSLANVLGKQEKYKESEGFFLNALKINPNVASCHGNLAVLYHRWGKLDLAKRHYELSLRLDPSAPGTKENYNMLKRKLEQRQRTVG", "length": 739 }, "evidence": [ { "id": "F1P0M3", "url": "https://omabrowser.org/oma/group/F1P0M3/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1MAQ6-1", "protein_name": "Protein O-mannosyl-transferase TMTC4", "gene_name": "Tmtc4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRSQLVLLAGTNGWGKLYWSPGFCPCTCIPSKLCTIAGTGISNQHNAGAGGWRPAVFKMAELDADLDHIIPSVLPPFWAKLVVGFVSLLCFARSYDGDFVFDDSEAIVNNKDLQSDTPLADLWHHDFWGSRLSSNTSHKSYRPLTVLTFRVNYYLSGGFHPVGFHVVNILLHGGISILMLDVFSVLFGGLQYSSKGRRVHLAPRASLLAALLFAVHPVHTECVAGVVGRADLLCALFFLLSFLGYCRAFKETGNKEGTHSSTFWVLLSIFLGAVAMLCKEQGVTVLGLNAVFDILVIGRLDILVAVRKVLRKDKSLESTGMLKNGGLLFRMALLTIGGSTMLYIRWKIMGTGPPAFTEVDNPASFADSVLVRAINYNYYYSLNAWLLLCPWWLCFDWSMGCIPLIKSVGDWRVIALAALWLCLIGLIFQALCSEDSCKRRILTLGLGFLVIPFLPASNLFFRVGFVVAERVLYLPSAGYCMLLTFGFGTLSRHTKKKKPVAAIILGILLINALRCVIRSGEWRSEDRLFRSALSVCPLNAKVHYNIGKNLADQGNQTAAIKYYREAVRLNPKYVHAMNNLGNILKERNELQEAEELLSLAVQIQPDFAAAWMNLGIVQNSLKRFEEAEQSYRTAIKHRRKYPDCYYNLGRLYADLNRHVDALNAWRNATVMKPEHSLAWNNMVILLDNTGNLAQAEAVGREALQLIPNDHSLMFSLANVLGKSQKYKESEALFLKAIKANPNVASYHGNLAVLYHRWGHLDSAKKHYEISLQLDPVAVGTKENYSLLRRKLEQMQKKDV", "length": 799 }, "evidence": [ { "id": "F1P0M3", "url": "https://omabrowser.org/oma/group/F1P0M3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3HGS4-1", "protein_name": "Protein O-mannosyl-transferase TMTC4", "gene_name": "Tmtc4", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAELDADLDHIIPSSVLSPFWAKLVVGFVSLVCFARSYDGDFVFDDSEAIINNKDLQSETPLGDLWHHDFWGSRLSSNTSHKSYRPLTVLTFRINYYLSGGFHPVGFHVVNILLHGGISILMLDVFSVLFGGLQYTSKGRRAHLAPRASLLATLLFAVHPVHTECVAGVVGRADLLCALFFLLSFLGYCQAFKESNKERTHFSTFWVLLSIFLGAVAMLCKEQGITVLGLNAVFDILVIGKFNILETVQKVLHKNKSLENIGALRNGGLLFRMTLLTLGGTSMLYVRWKIMGTGPPAFTEVDNPASFADSVLVRAINYNYYYSLNAWLLLCPWWLCFDWSMGCIPLIKSVGDWRVIALAALWLCLIGLMFQALCSEDGCKRRILTLGLGFLVIPFLPASNLFFRVGFVVAERVLYLPSAGYCMLLTFGFGALSRHTKKKRPVAAIVLGILLINALRCVIRSGEWRSEDRLFRSALSVCPLNAKVHYNIGKNLADQGNQTAAIRYYREAVRLNPKYIHAMNNLGNILKERNELQEAEELLSLAVQIQPDFAAAWMNLGIVQNSLKRFEAAEQSYRTAIKHRRKYPDCYYNLGRLYADLNRHVDALNAWRNATVLKPEHSLAWNNMIILLDNTGNLAQAEAVGREALELIPNDHSLMFSLANVLGKAQKYKESEALFLKAIKANPNVASYHGNLAVLYHRWGHLDSAKKHYEISLQLDPVAAGTKENYSLLRRKLEQMHRKDG", "length": 741 }, "evidence": [ { "id": "F1P0M3", "url": "https://omabrowser.org/oma/group/F1P0M3/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q5T4D3-1", "protein_name": "Protein O-mannosyl-transferase TMTC4", "gene_name": "TMTC4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAVLDTDLDHILPSSVLPPFWAKLVVGSVAIVCFARSYDGDFVFDDSEAIVNNKDLQAETPLGDLWHHDFWGSRLSSNTSHKSYRPLTVLTFRINYYLSGGFHPVGFHVVNILLHSGISVLMVDVFSVLFGGLQYTSKGRRLHLAPRASLLAALLFAVHPVHTECVAGVVGRADLLCALFFLLSFLGYCKAFRESNKEGAHSSTFWVLLSIFLGAVAMLCKEQGITVLGLNAVFDILVIGKFNVLEIVQKVLHKDKSLENLGMLRNGGLLFRMTLLTSGGAGMLYVRWRIMGTGPPAFTEVDNPASFADSMLVRAVNYNYYYSLNAWLLLCPWWLCFDWSMGCIPLIKSISDWRVIALAALWFCLIGLICQALCSEDGHKRRILTLGLGFLVIPFLPASNLFFRVGFVVAERVLYLPSVGYCVLLTFGFGALSKHTKKKKLIAAVVLGILFINTLRCVLRSGEWRSEEQLFRSALSVCPLNAKVHYNIGKNLADKGNQTAAIRYYREAVRLNPKYVHAMNNLGNILKERNELQEAEELLSLAVQIQPDFAAAWMNLGIVQNSLKRFEAAEQSYRTAIKHRRKYPDCYYNLGRLYADLNRHVDALNAWRNATVLKPEHSLAWNNMIILLDNTGNLAQAEAVGREALELIPNDHSLMFSLANVLGKSQKYKESEALFLKAIKANPNAASYHGNLAVLYHRWGHLDLAKKHYEISLQLDPTASGTKENYGLLRRKLELMQKKAV", "length": 741 }, "evidence": [ { "id": "F1P0M3", "url": "https://omabrowser.org/oma/group/F1P0M3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8BG19-1", "protein_name": "Protein O-mannosyl-transferase TMTC4", "gene_name": "Tmtc4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVELDADLDHIVPSVLPPFWAKLVVGFVSLLCFARSYDGDFVFDDSEAIVNNKDLQSDTPLGDLWHHDFWGSKLSSNTSHKSYRPLTVLTFRINYYLSGGFHPVGFHVVNILLHGSISILMLDVFSVLFGGLQYTGKGQRVHLAPRASLLATLLFAVHPVHTECVAGVVGRADLLCALFFLLSFLGYCQAFKETGNKEGTHSSTFWVLLSIFLGAVAMLCKEQGITVLGLNAVFDILVIGKLDILAAVRKVLHKDKSQENAGMFKNGGLLFRIALLTIGGTSMLYIRWKIMGTGPPAFTEVDNPASFADSMLVRAINYNYYYSLNAWLLLCPWWLCFDWSMGCIPLIKSVGDWRVIALAALWLCLIGLIFQALCSEDSCKRRILTLGLGFLVIPFLPASNLFFRVGFVVAERVLYLPSAGYCVLLTFGFGALSRHTKKKKPVAAIILGILLINALRCVIRSGEWRSEEQLFRSALSVCPLNAKVHYNIGKNLADQGNQTAAIKYYREAVRLNPKYVHAMNNLGNILKERNELQEAEELLSLAVQIQPDFAAAWMNLGIVQNSLKRFEEAEQSYRTAIKHRRKYPDCYYNLGRLYADLNRHVDALNAWRNATVLKPEHSLAWNNMIILLDNTGNLAQAEAVGREALQLIPNDHSLMFSLANVLGKSQKYKESEALFLKAIKANPNVASYHGNLAVLYHRWGHLDSAKKHYEISLQLDPVAVGTKENYSLLRRKLEQTQKKDV", "length": 741 }, "evidence": [ { "id": "F1P0M3", "url": "https://omabrowser.org/oma/group/F1P0M3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VF81-1", "protein_name": "Protein O-mannosyl-transferase Tmtc4", "gene_name": "Tmtc4", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MLDLVHKATLHSMVCQAILVLICLLCYGCGGLSGAKFVFDDTVAIVKNRDVNSLPTNWTAIFTHDFWGASLLSSDSHKSFRPLTTLMFHCEYALLGLSAAHMKFLNLLLHCVNTLLMWRLIRSLYVPEVSTARWAILSAALFAAHPIHTEAVSGVVGRAELMFGMIHLLCLLLTVANTGRLGPQTGGLIMLLTAVGMLFKESAVTIPMSCVLLDYFQNGYYHLRFKDQWSLLRTRISYLFYLLGTLGLLTARLWWQDFETPTFKEVDNPVAHNEHVLTRGLSQQYLLVMNIWLMLCPHWLCYDWALGCVKLVTNIWDLRLQGVIGFYSIVLVALMNFRRLPGMMLALGLMIVPFLPASGIICVGFVIAERTLYVPSIGFCLLSIYGFLYWYDSSTENTHWRTALRILLMLLFSVMMVRTRQRATDWLNEEQLFKSALQVCPDNAKVHYNIARLATDMGNNTKAFQHYHRAIELYPNYESALMNLGNLYREHGQLSTAEEYIRLALQAYPAFPAAWMNLGIVQSAQGKYDKALASYEKALKYRANFAVCYYNMGNLYLEQKRYAEALHHWQHAVALNPRQPKAWANILTMLDNKGLQDDALRISNQALQHLPNDVSILFIRANVLGKLKHYTEAEAIYKRVIELEPHNTLYHTNLGVLYHRWDKTQEAIEAYRTAISISAARATTARENLSKLLKRLEREAQVMQR", "length": 705 }, "evidence": [ { "id": "F1P0M3", "url": "https://omabrowser.org/oma/group/F1P0M3/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "dolichyl-phosphate-mannose-protein mannosyltransferase activity", "id": "GO:0004169", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004169", "evidence": [ { "database": "UniProtKB", "id": "F1P0M3", "url": "https://www.uniprot.org/uniprotkb/F1P0M3" } ], "pmid": "" }, { "name": "ATPase binding", "id": "GO:0051117", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051117", "evidence": [ { "database": "UniProtKB", "id": "F1P0M3", "url": "https://www.uniprot.org/uniprotkb/F1P0M3" } ], "pmid": "" }, { "name": "mannosyltransferase activity", "id": "GO:0000030", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000030", "evidence": [ { "database": "UniProtKB", "id": "F1P0M3", "url": "https://www.uniprot.org/uniprotkb/F1P0M3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "F1P0M3", "url": "https://www.uniprot.org/uniprotkb/F1P0M3" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "F1P0M3", "url": "https://www.uniprot.org/uniprotkb/F1P0M3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "endoplasmic reticulum unfolded protein response", "id": "GO:0030968", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030968", "evidence": [ { "database": "UniProtKB", "id": "F1P0M3", "url": "https://www.uniprot.org/uniprotkb/F1P0M3" } ], "pmid": "" }, { "name": "protein O-linked glycosylation via mannose", "id": "GO:0035269", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035269", "evidence": [ { "database": "UniProtKB", "id": "F1P0M3", "url": "https://www.uniprot.org/uniprotkb/F1P0M3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 200, "end_pos": 202, "annotation": "n_glycosylation_sequon" }, { "start_pos": 495, "end_pos": 497, "annotation": "n_glycosylation_sequon" }, { "start_pos": 607, "end_pos": 609, "annotation": "n_glycosylation_sequon" }, { "start_pos": 78, "end_pos": 80, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1P0M3-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 740, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1P0M3-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1P0M3" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1P0M3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P0M3" }, { "id": "PF08409", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08409" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "DUF1736", "eco_id": "ECO_0000259", "start_pos": 292, "end_pos": 364, "start_aa": "Gly", "end_aa": "Ile", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.4.1.109", "ec_name": "a di-trans,poly-cis-dolichyl beta-D-mannosyl phosphate + L-threonyl-[protein] = 3-O-(alpha-D-mannosyl)-L-threonyl-[protein] + a di-trans,poly-cis-dolichyl phosphate + H(+).", "evidence": [ { "id": "2.4.1.109", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.1.109" }, { "id": "2.4.1.109", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.4.1.109" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 200, "end_pos": 202 }, { "start_pos": 495, "end_pos": 497 }, { "start_pos": 607, "end_pos": 609 }, { "start_pos": 78, "end_pos": 80 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1NWK2-1", "uniprot_ac": "F1NWK2", "uniprot_id": "F1NWK2_CHICK", "mass": { "chemical_mass": 9596.0, "monoisotopic_mass": 9596.0 }, "refseq": { "ac": "NP_001185711", "name": "cytochrome c oxidase subunit 7A2, mitochondrial", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001185711" }, "gene_names": [ { "name": "COX7A2", "type": "recommended", "evidence": [ { "id": "F1NWK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NWK2" } ] }, { "name": "COX7A2", "type": "synonym", "evidence": [ { "id": "NP_001185711", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001185711" } ] } ], "protein_names": [ { "name": "Cytochrome c oxidase subunit 7A2, mitochondrial", "type": "recommended", "evidence": [ { "id": "F1NWK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NWK2/entry#names_and_taxonomy" } ] }, { "name": "Cytochrome c oxidase subunit VIIa-liver/heart", "type": "synonym", "evidence": [ { "id": "F1NWK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NWK2/entry#names_and_taxonomy" } ] }, { "name": "cytochrome c oxidase subunit 7A2, mitochondrial", "type": "synonym", "evidence": [ { "id": "NP_001185711", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001185711" } ] }, { "name": "cytochrome c oxidase subunit VIIa polypeptide 2 (liver)", "type": "synonym", "evidence": [ { "id": "NP_001185711", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001185711" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: BU386564.1, BX931842.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: inferred from homology ##RefSeq-Attributes-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BX257969.4, BX930729.2 and BX257968.2. On Nov 11, 2010 this sequence version replaced XP_001235422.1. Sequence Note: This RefSeq record was created from transcripts from multiple strains because no single transcript from the same strain was available for the full length of the gene. The extent of this transcript is supported by transcript alignments and orthologous data.", "evidence": [ { "database": "RefSeq", "id": "NP_001185711", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001185711" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NWK2", "url": "https://www.uniprot.org/uniprotkb/F1NWK2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "COX7A2", "url": "https://www.uniprot.org/uniprotkb/F1NWK2", "locus": { "chromosome": "3", "start_pos": 80488192, "end_pos": 80478901, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010004076", "url": "https://www.ensembl.org/id/ENSGALG00010004076" } ] } } ], "crossref": [ { "id": "F1NWK2", "url": "https://alphafold.ebi.ac.uk/entry/F1NWK2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000015906", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000015906", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00928", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00928", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "772260", "url": "https://www.ncbi.nlm.nih.gov/gene/772260", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003177", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003177", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036539", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036539", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039297", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039297", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:772260", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:772260", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WAVTAKM", "url": "https://omabrowser.org/oma/group/WAVTAKM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XIK8", "url": "https://www.orthodb.org/?gene=A0A8V0XIK8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NWK2", "url": "https://www.orthodb.org/?gene=F1NWK2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10510", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10510", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10510:SF15", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10510:SF15", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02238", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02238", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-5628897", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5628897", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-611105", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-611105", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9707564", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9707564", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001185711", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001185711", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0XIK8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XIK8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XIK8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XIK8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NWK2", "url": "https://www.uniprot.org/uniprotkb/F1NWK2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NWK2-1", "url": "https://www.uniprot.org/uniprotkb/F1NWK2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MWRNLLSLRQVSQRTISTASRRLLENRVPEKQKLFQEDNGLPVYLKGGIMDGLLYRVTMGLTVFGTGYVLYELMMASMPKKQK", "length": 83, "header": "tr|F1NWK2-1|F1NWK2_CHICK Isoform 1 of Cytochrome c oxidase subunit 7A2, mitochondrial OS=Gallus gallus OX=9031 GN=COX7A2 PE=1 SV=2 CANONICAL=F1NWK2-1" }, "isoforms": [ { "isoform_ac": "A0A8V0XIK8-1", "url": "https://www.uniprot.org/uniprotkb/F1NWK2/entry#A0A8V0XIK8-1", "sequence": { "sequence": "MWRNLLVRGPSLRQVSQRTISTASRRLLENRVPEKQKLFQEDNGLPVYLKGGIMDGLLYRVTMGLTVFGTGYVLYELMMASMPKKQK", "length": 87, "header": "tr|A0A8V0XIK8-1|F1NWK2_CHICK Computationally mapped isoform of Cytochrome c oxidase subunit 7A2, mitochondrial OS=Gallus gallus OX=9031 GN=COX7A2 PE=1 SV=1 CANONICAL=F1NWK2-1" }, "locus": { "chromosome": "3", "start_pos": 80487540, "end_pos": 80484920, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010009463.1", "url": "https://www.ensembl.org/id/ENSGALT00010009463.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010005586.1", "url": "https://www.ensembl.org/id/ENSGALP00010005586.1" } ] } }, { "isoform_ac": "F1NWK2-1", "url": "https://www.uniprot.org/uniprotkb/F1NWK2/entry#F1NWK2-1", "sequence": { "sequence": "MWRNLLSLRQVSQRTISTASRRLLENRVPEKQKLFQEDNGLPVYLKGGIMDGLLYRVTMGLTVFGTGYVLYELMMASMPKKQK", "length": 83, "header": "tr|F1NWK2-1|F1NWK2_CHICK Isoform 1 of Cytochrome c oxidase subunit 7A2, mitochondrial OS=Gallus gallus OX=9031 GN=COX7A2 PE=1 SV=2 CANONICAL=F1NWK2-1" }, "locus": { "chromosome": "3", "start_pos": 80487540, "end_pos": 80484920, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010009464.1", "url": "https://www.ensembl.org/id/ENSGALT00010009464.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010005587.1", "url": "https://www.ensembl.org/id/ENSGALP00010005587.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:772260", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:772260", "resource": "KEGG Pathway" }, { "id": "R-GGA-5628897", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5628897", "resource": "Reactome", "description": "TP53 Regulates Metabolic Genes" }, { "id": "R-GGA-611105", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-611105", "resource": "Reactome", "description": "Respiratory electron transport" }, { "id": "R-GGA-9707564", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9707564", "resource": "Reactome", "description": "Cytoprotection by HMOX1" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3L7HVM8-1", "protein_name": "Cytochrome c oxidase subunit 7A2, mitochondrial", "gene_name": "LOC100756540", "tax_id": 10029, 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"MLRNVLALRQIAQRTISTTSRRHFENKVPEKQKLFQEDNGMPVHLKGGTSDALLYRATMLLTVGGTAYAIYMLAMAAFPKKQN", "length": 83 }, "evidence": [ { "id": "F1NWK2", "url": "https://omabrowser.org/oma/group/F1NWK2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P48771-1", "protein_name": "Cytochrome c oxidase subunit 7A2, mitochondrial", "gene_name": "Cox7a2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLRNLLALRQIAQRTISTTSRRHFENKVPEKQKLFQEDNGMPVHLKGGASDALLYRATMALTLGGTAYAIYLLAMAAFPKKQN", "length": 83 }, "evidence": [ { "id": "F1NWK2", "url": "https://omabrowser.org/oma/group/F1NWK2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "F1NWK2", "url": 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"F1P1B2_CHICK", "mass": { "chemical_mass": 139261.0, "monoisotopic_mass": 139261.0 }, "refseq": { "ac": "NP_001026242", "name": "adhesion G-protein coupled receptor G6 precursor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026242" }, "gene_names": [ { "name": "ADGRG6", "type": "recommended", "evidence": [ { "id": "F1P1B2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P1B2" } ] }, { "name": "ADGRG6", "type": "synonym", "evidence": [ { "id": "NP_001026242", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026242" } ] }, { "name": "GPR126", "type": "synonym", "evidence": [ { "id": "NP_001026242", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026242" } ] } ], "protein_names": [ { "name": "Adhesion G-protein coupled receptor G6", "type": "recommended", "evidence": [ { "id": "F1P1B2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P1B2/entry#names_and_taxonomy" } ] }, { "name": "Developmentally regulated G-protein-coupled receptor", "type": "synonym", "evidence": [ { "id": "F1P1B2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P1B2/entry#names_and_taxonomy" } ] }, { "name": "G protein-coupled receptor 126", "type": "synonym", "evidence": [ { "id": "NP_001026242", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026242" } ] }, { "name": "G-protein coupled receptor 126", "type": "synonym", "evidence": [ { "id": "F1P1B2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P1B2/entry#names_and_taxonomy" } ] }, { "name": "adhesion G-protein coupled receptor G6 precursor", "type": "synonym", "evidence": [ { "id": "NP_001026242", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026242" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ851754.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA103992290, SAMEA103992323 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000063.1. On Mar 5, 2015 this sequence version replaced NP_001026242.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001026242", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026242" } ] }, { "annotation": "Adhesion G-protein coupled receptor (aGPCR) for steroid hormones, such as progesterone and 17alpha-hydroxyprogesterone (17OHP). Involved in many biological processes, such as myelination, sprouting angiogenesis, placenta, ear and cartilage development. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of downstream effectors, such as adenylate cyclase. ADGRG6 is coupled to G(i) G alpha proteins and mediates inhibition of adenylate cyclase. Also able to couple to G(q) G proteins. Involved in myelination of the peripheral nervous system: required for differentiation of promyelinating Schwann cells and for normal myelination of axons. Also acts as a regulator of body length and bone mass. Acts as a regulator of blood-brain barrier formation in the central nervous system vie its association with LRP1 and ITGB1.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0XJ23", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XJ23#function" }, { "database": "UniProtKB", "id": "ARBA00093343", "url": "https://www.uniprot.org/uniprotkb/ARBA00093343#function" }, { "database": "UniProtKB", "id": "A0A8V0XJ28", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XJ28#function" }, { "database": "UniProtKB", "id": "A0A8V0XT71", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XT71#function" }, { "database": "UniProtKB", "id": "F1P1B2", "url": "https://www.uniprot.org/uniprotkb/F1P1B2#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1P1B2", "url": "https://www.uniprot.org/uniprotkb/F1P1B2" } ], "common_name": "Chicken", 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{ "id": "F1P1B2", "url": "https://www.uniprot.org/uniprotkb/F1P1B2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1P1B2-1", "url": "https://www.uniprot.org/uniprotkb/F1P1B2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MMSHINEMWCCHWKWKLQHCLYLFILYIICMQQAAHGCYNCRTVLTDPSGVFTSPCYPSDYPNSQACKWIIRAPHGFIIQLTFSDFDIEEAPGCIYDSLTLDNGESPMNLCGITAKGLSYNSTGNEMIVSFKSDFSIQKKGFNASYVRIAVSLRNQKVIIPQDPDADAVSVAETVLVPELSQFTLCFEATKSSSDDNDDWKIFSYTDASSKEFFGFGKTAKGHFLSISDTQCILDNALPQNAEFFTGTFEQLCVVGDSFSGTIGVYAKSIYHNTYCPDMFGKVIPGNGRLVLGSNSNEVSSLNGDIYNFRLWNFTMNAQTLANLSCDVKGNIVDWENEFWSIPTSALKAENNLSCGSYLIPSSAIEPTSCANLGSLCQATVNATTPTPPTVTTNMPDTNRTDKPNNGGLFYRISITVFSYNSNSESKVHDVVAEWLNHTFQNWNYTVYVVNISIQPGTIKEAVREKRNIDSKRFEVLALLVYNATNNINLEEQDIRQKLINNNESIAEGYRLHTVEVDPVEKCLAEENPPNYFWPDTRPTVTNFTFCHGSSVQIASRTCYLGLQNYTSYWGQPDLRNCTENAADIANQLLNLTGEGQQLTSDKVNDVVQKLKKIVNDEEIDESLGSTVVTIFSNILNSSDSVLAASSSEALKTIDALALKIQFTGPSMSISTRNLALGVSSVNSTSFKGSSFSVSPQNNASDFQIDFDKDQTNAIASVILPPSLLKNLSQDDFEVISRAQFTFFNKNGLFQDAETPGNLTSFVVACSIGNITIRDLQEYVKITIKHTKIQEDPKPTCVFWDMAKNGGNGGWNPTGCKVQADSNENETVCLCNHLTHFGVLMDLQGTATEIDAQNTKILTFITYIGCGISAIFSAATLLTYIAFEKLRRDYPSKILMNLSTALLFLNLTFLLDGWIASFDIDGLCIAIAALLHYFLLATFTWMGLEAVHMYIALVKVFNTYIRRYILKFCIIGWGLPALVIAIVLASTNKNASRVYGKELYGRDATGQGGDDFCWIKNKVVFYVTCAGYFGIMFLLNVAMFVVVMVQICGRNGKRTNRTLKEEILRNLRSVVSLTFLLGMTWGFAFFAWGPLTLPFLYLFSIFNSLQGLFIFVFHCAMKENVQKQWRRHLCCGRFRLADNSDWSKTATNIIKKSSDNLGKSLSSSSIGSNSTYLTSKSKSTTNTYCKRSSHTENIFVDKPPSKFAQEDGEQTSIIPVHQVIDKVKGYCNSHSDNFYKNIIMSDTFSHSTKF", "length": 1250, "header": "tr|F1P1B2-1|F1P1B2_CHICK Isoform 1 of Adhesion G-protein coupled receptor G6 OS=Gallus gallus OX=9031 GN=ADGRG6 PE=3 SV=2 CANONICAL=F1P1B2-1" }, "isoforms": [ { "isoform_ac": "A0A8V0XJ23-1", "url": "https://www.uniprot.org/uniprotkb/F1P1B2/entry#A0A8V0XJ23-1", "sequence": { "sequence": "MSHINEMWCCHWKWKLQHCLYLFILYIICMQQAAHGCYNCRTVLTDPSGVFTSPCYPSDYPNSQACKWIIRAPHGFIIQLTFSDFDIEEAPGCIYDSLTLDNGESPMNLCGITAKGLSYNSTGNEMIVSFKSDFSIQKKGFNASYVRIAVSLRNQKVIIPQDPDADAVSVAETVLVPELSQFTLCFEATKSSSDDNDDWKIFSYTDASSKEFFGFGKTAKGHFLSISDTQCILDNALPQNAEFFTGTFEQLCVVGDSFSGTIGVYAKSIYHNTYCPDMFGKVIPGNGRLVLGSNSNEVSSLNGDIYNFRLWNFTMNAQTLANLSCDVKGNIVDWENEFWSIPTSALKAENNLSCGSYLIPSSAIEPTSCANLGSLCQATVNATTPTPPTVTTNMPDTNRTDKPNNGGLFYRISITVFSYNSNSESKVHDVVAEWLNHTFQNWNYTVYVVNISIQPGTIKEAVREKRNIDSKRFEVLALLVYNATNNINLEEQDIRQKLINNNESIAEGYRLHTVEVDPVEKCLAEENPPNYFWPDTRPTVTNFTFCHGSSVQIASRTCYLGLQNYTSYWGQPDLRNCTENAADIANQLLNLTGEGQQLTSDKVNDVVQKLKKIVNDEEIDESLGSTVVTIFSNILNSSDSVLAASSSEALKTIDALALKIQFTGPSMSISTRNLALGVSSVNSTSFKGSSFSVSPQNNASDFQIDFDKDQTNAIASVILPPSLLKNLSQDDFEVISRAQFTFFNKNGLFQDAETPGNLTSFVVACSYSFFISTGGNGGWNPTGCKVQADSNENETVCLCNHLTHFGVLMDLQGTATEIDAQNTKILTFITYIGCGISAIFSAATLLTYIAFEKLRRDYPSKILMNLSTALLFLNLTFLLDGWIASFDIDGLCIAIAALLHYFLLATFTWMGLEAVHMYIALVKVFNTYIRRYILKFCIIGWGLPALVIAIVLASTNKNASRVYGKELYGRDATGQGGDDFCWIKNKVVFYVTCAGYFGIMFLLNVAMFVVVMVQICGRNGKRTNRTLKEEILRNLRSVVSLTFLLGMTWGFAFFAWGPLTLPFLYLFSIFNSLQGRLNFFFL", "length": 1082, "header": "tr|A0A8V0XJ23-1|F1P1B2_CHICK Computationally mapped isoform of Adhesion G-protein coupled receptor G6 OS=Gallus gallus OX=9031 GN=ADGRG6 PE=3 SV=1 CANONICAL=F1P1B2-1" }, "locus": { "chromosome": "3", "start_pos": 52652470, "end_pos": 52562195, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010013801.1", "url": "https://www.ensembl.org/id/ENSGALT00010013801.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010008163.1", "url": "https://www.ensembl.org/id/ENSGALP00010008163.1" } ] } }, { "isoform_ac": "A0A8V0XJ28-1", "url": "https://www.uniprot.org/uniprotkb/F1P1B2/entry#A0A8V0XJ28-1", "sequence": { "sequence": "MMSHINEMWCCHWKWKLQHCLYLFILYIICMQQAAHGCYNCRTVLTDPSGVFTSPCYPSDYPNSQACKWIIRAPHGFIIQLTFSDFDIEEAPGCIYDSLTLDNGESPMNLCGITAKGLSYNSTGNEMIVSFKSDFSIQKKGFNASYVRIAVSLRNQKVIIPQDPDADAVSVAETVLVPELSQFTLCFEATKSSSDDNDDWKIFSYTDASSKEFFGFGKTAKGHFLSISDTQCILDNALPQNAEFFTGTFEQLCVVGDSFSGTIGVYAKSIYHNTYCPDMFGKVIPGNGRLVLGSNSNEVSSLNGDIYNFRLWNFTMNAQTLANLSCDVKGNIVDWENEFWSIPTSALKAENNLSCGSYLIPSSAIEPTSCANLGSLCQGGLFYRISITVFSYNSNSESKVHDVVAEWLNHTFQNWNYTVYVVNISIQPGTIKEAVREKRNIDSKRFEVLALLVYNATNNINLEEQDIRQKLINNNESIAEGYRLHTVEVDPVEKCLAEENPPNYFWPDTRPTVTNFTFCHGSSVQIASRTCYLGLQNYTSYWGQPDLRNCTENAADIANQLLNLTGEGQQLTSDKVNDVVQKLKKIVNDEEIDESLGSTVVTIFSNILNSSDSVLAASSSEALKTIDALALKIQFTGPSMSISTRNLALGVSSVNSTSFKGSSFSVSPQNNASDFQIDFDKDQTNAIASVILPPSLLKNLSQDDFEVISRAQFTFFNKNGLFQDAETPGNLTSFVVACSIGNITIRDLQEYVKITIKHTKIQEDPKPTCVFWDMAKNGGNGGWNPTGCKVQADSNENETVCLCNHLTHFGVLMDLQGTATEIDAQNTKILTFITYIGCGISAIFSAATLLTYIAFEKLRRDYPSKILMNLSTALLFLNLTFLLDGWIASFDIDGLCIAIAALLHYFLLATFTWMGLEAVHMYIALVKVFNTYIRRYILKFCIIGWGLPALVIAIVLASTNKNASRVYGKELYGRDATGQGGDDFCWIKNKVVFYVTCAGYFGIMFLLNVAMFVVVMVQICGRNGKRTNRTLKEEILRNLRSVVSLTFLLGMTWGFAFFAWGPLTLPFLYLFSIFNSLQGLFIFVFHCAMKENVQKQWRRHLCCGRFRLADNSDWSKTATNIIKKSSDNLGKSLSSSSIGSNSTYLTSKSKSTTNTYCKRSSHTENIFVDKPPSKFAQEDGEQTSIIPVHQVIDKVKGYCNSHSDNFYKNIIMSDTFSHSTKF", "length": 1222, "header": "tr|A0A8V0XJ28-1|F1P1B2_CHICK Computationally mapped isoform of Adhesion G-protein coupled receptor G6 OS=Gallus gallus OX=9031 GN=ADGRG6 PE=3 SV=1 CANONICAL=F1P1B2-1" }, "locus": { "chromosome": "3", "start_pos": 52658317, "end_pos": 52551579, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010013815.1", "url": "https://www.ensembl.org/id/ENSGALT00010013815.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010008168.1", "url": "https://www.ensembl.org/id/ENSGALP00010008168.1" } ] } }, { "isoform_ac": "A0A8V0XT71-1", "url": "https://www.uniprot.org/uniprotkb/F1P1B2/entry#A0A8V0XT71-1", "sequence": { "sequence": "MQCCTKEELCLLLTGIACWMSHINEMWCCHWKWKLQHCLYLFILYIICMQQAAHGCYNCRTVLTDPSGVFTSPCYPSDYPNSQACKWIIRAPHGFIIQLTFSDFDIEEAPGCIYDSLTLDNGESPMNLCGITAKGLSYNSTGNEMIVSFKSDFSIQKKGFNASYVRIAVSLRNQKVIIPQDPDADAVSVAETVLVPELSQFTLCFEATKSSSDDNDDWKIFSYTDASSKEFFGFGKTAKGHFLSISDTQCILDNALPQNAEFFTGTFEQLCVVGDSFSGTIGVYAKSIYHNTYCPDMFGKVIPGNGRLVLGSNSNEVSSLNGDIYNFRLWNFTMNAQTLANLSCDVKGNIVDWENEFWSIPTSALKAENNLSCGSYLIPSSAIEPTSCANLGSLCQGGLFYRISITVFSYNSNSESKVHDVVAEWLNHTFQNWNYTVYVVNISIQPGTIKEAVREKRNIDSKRFEVLALLVYNATNNINLEEQDIRQKLINNNESIAEGYRLHTVEVDPVEKCLAEENPPNYFWPDTRPTVTNFTFCHGSSVQIASRTCYLGLQNYTSYWGQPDLRNCTENAADIANQLLNLTGEGQQLTSDKVNDVVQKLKKIVNDEEIDESLGSTVVTIFSNILNSSDSVLAASSSEALKTIDALALKIQFTGPSMSISTRNLALGVSSVNSTSFKGSSFSVSPQNNASDFQIDFDKDQTNAIASVILPPSLLKNLSQDDFEVISRAQFTFFNKNGLFQDAETPGNLTSFVVACSIGNITIRDLQEYVKITIKHTKIQEDPKPTCVFWDMAKNGGNGGWNPTGCKVQADSNENETVCLCNHLTHFGVLMDLQGTATEIDAQNTKILTFITYIGCGISAIFSAATLLTYIAFEKLRRDYPSKILMNLSTALLFLNLTFLLDGWIASFDIDGLCIAIAALLHYFLLATFTWMGLEAVHMYIALVKVFNTYIRRYILKFCIIGWGLPALVIAIVLASTNKNASRVYGKELYGRDATGQGGDDFCWIKNKVVFYVTCAGYFGIMFLLNVAMFVVVMVQICGRNGKRTNRTLKEEILRNLRSVVSLTFLLGMTWGFAFFAWGPLTLPFLYLFSIFNSLQGLFIFVFHCAMKENVQKQWRRHLCCGRFRLADNSDWSKTATNIIKKSSDNLGKSLSSSSIGSNSTYLTSKSKSTTNTYCKRSSHTDNVF", "length": 1185, "header": "tr|A0A8V0XT71-1|F1P1B2_CHICK Computationally mapped isoform of Adhesion G-protein coupled receptor G6 OS=Gallus gallus OX=9031 GN=ADGRG6 PE=3 SV=1 CANONICAL=F1P1B2-1" }, "locus": { "chromosome": "3", "start_pos": 52661309, "end_pos": 52554246, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010013823.1", "url": "https://www.ensembl.org/id/ENSGALT00010013823.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010008171.1", "url": "https://www.ensembl.org/id/ENSGALP00010008171.1" } ] } }, { "isoform_ac": "F1P1B2-1", "url": "https://www.uniprot.org/uniprotkb/F1P1B2/entry#F1P1B2-1", "sequence": { "sequence": "MMSHINEMWCCHWKWKLQHCLYLFILYIICMQQAAHGCYNCRTVLTDPSGVFTSPCYPSDYPNSQACKWIIRAPHGFIIQLTFSDFDIEEAPGCIYDSLTLDNGESPMNLCGITAKGLSYNSTGNEMIVSFKSDFSIQKKGFNASYVRIAVSLRNQKVIIPQDPDADAVSVAETVLVPELSQFTLCFEATKSSSDDNDDWKIFSYTDASSKEFFGFGKTAKGHFLSISDTQCILDNALPQNAEFFTGTFEQLCVVGDSFSGTIGVYAKSIYHNTYCPDMFGKVIPGNGRLVLGSNSNEVSSLNGDIYNFRLWNFTMNAQTLANLSCDVKGNIVDWENEFWSIPTSALKAENNLSCGSYLIPSSAIEPTSCANLGSLCQATVNATTPTPPTVTTNMPDTNRTDKPNNGGLFYRISITVFSYNSNSESKVHDVVAEWLNHTFQNWNYTVYVVNISIQPGTIKEAVREKRNIDSKRFEVLALLVYNATNNINLEEQDIRQKLINNNESIAEGYRLHTVEVDPVEKCLAEENPPNYFWPDTRPTVTNFTFCHGSSVQIASRTCYLGLQNYTSYWGQPDLRNCTENAADIANQLLNLTGEGQQLTSDKVNDVVQKLKKIVNDEEIDESLGSTVVTIFSNILNSSDSVLAASSSEALKTIDALALKIQFTGPSMSISTRNLALGVSSVNSTSFKGSSFSVSPQNNASDFQIDFDKDQTNAIASVILPPSLLKNLSQDDFEVISRAQFTFFNKNGLFQDAETPGNLTSFVVACSIGNITIRDLQEYVKITIKHTKIQEDPKPTCVFWDMAKNGGNGGWNPTGCKVQADSNENETVCLCNHLTHFGVLMDLQGTATEIDAQNTKILTFITYIGCGISAIFSAATLLTYIAFEKLRRDYPSKILMNLSTALLFLNLTFLLDGWIASFDIDGLCIAIAALLHYFLLATFTWMGLEAVHMYIALVKVFNTYIRRYILKFCIIGWGLPALVIAIVLASTNKNASRVYGKELYGRDATGQGGDDFCWIKNKVVFYVTCAGYFGIMFLLNVAMFVVVMVQICGRNGKRTNRTLKEEILRNLRSVVSLTFLLGMTWGFAFFAWGPLTLPFLYLFSIFNSLQGLFIFVFHCAMKENVQKQWRRHLCCGRFRLADNSDWSKTATNIIKKSSDNLGKSLSSSSIGSNSTYLTSKSKSTTNTYCKRSSHTENIFVDKPPSKFAQEDGEQTSIIPVHQVIDKVKGYCNSHSDNFYKNIIMSDTFSHSTKF", "length": 1250, "header": "tr|F1P1B2-1|F1P1B2_CHICK Isoform 1 of Adhesion G-protein coupled receptor G6 OS=Gallus gallus OX=9031 GN=ADGRG6 PE=3 SV=2 CANONICAL=F1P1B2-1" }, "locus": { "chromosome": "3", "start_pos": 52658317, "end_pos": 52551579, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010013809.1", "url": "https://www.ensembl.org/id/ENSGALT00010013809.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010008165.1", "url": "https://www.ensembl.org/id/ENSGALP00010008165.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 387, "start_aa": "Thr", "end_pos": 387, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr387", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:421673", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:421673", "resource": "KEGG Pathway" }, { "id": "R-GGA-9619665", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9619665", "resource": "Reactome", "description": "EGR2 and SOX10-mediated initiation of Schwann cell myelination" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "F1P1B2", "url": "https://www.uniprot.org/uniprotkb/F1P1B2" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "F1P1B2", "url": "https://www.uniprot.org/uniprotkb/F1P1B2" } ], "pmid": "" }, { "name": "laminin binding", "id": "GO:0043236", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043236", "evidence": [ { "database": "UniProtKB", "id": "F1P1B2", "url": "https://www.uniprot.org/uniprotkb/F1P1B2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F1P1B2", "url": "https://www.uniprot.org/uniprotkb/F1P1B2" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1P1B2", "url": "https://www.uniprot.org/uniprotkb/F1P1B2" } ], "pmid": "" }, { "name": "cell surface", "id": "GO:0009986", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009986", "evidence": [ { "database": "UniProtKB", "id": "F1P1B2", "url": "https://www.uniprot.org/uniprotkb/F1P1B2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 8, "go_terms": [ { "name": "cell surface receptor signaling pathway", "id": "GO:0007166", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007166", "evidence": [ { "database": "UniProtKB", "id": "F1P1B2", "url": "https://www.uniprot.org/uniprotkb/F1P1B2" } ], "pmid": "" }, { "name": "myelination", "id": "GO:0042552", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042552", "evidence": [ { "database": "UniProtKB", "id": "F1P1B2", "url": "https://www.uniprot.org/uniprotkb/F1P1B2" } ], "pmid": "" }, { "name": "adenylate cyclase-modulating G protein-coupled receptor signaling pathway", "id": "GO:0007188", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007188", "evidence": [ { "database": "UniProtKB", "id": "F1P1B2", "url": "https://www.uniprot.org/uniprotkb/F1P1B2" } ], "pmid": "" }, { "name": "Schwann cell differentiation", "id": "GO:0014037", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0014037", "evidence": [ { "database": "UniProtKB", "id": "F1P1B2", "url": "https://www.uniprot.org/uniprotkb/F1P1B2" } ], "pmid": "" }, { "name": "adenylate cyclase-activating G protein-coupled receptor signaling pathway", "id": "GO:0007189", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007189", "evidence": [ { "database": "UniProtKB", "id": "F1P1B2", "url": "https://www.uniprot.org/uniprotkb/F1P1B2" } ], "pmid": "" }, { "name": "adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway", "id": "GO:0007193", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007193", "evidence": [ { "database": "UniProtKB", "id": "F1P1B2", "url": "https://www.uniprot.org/uniprotkb/F1P1B2" } ], "pmid": "" }, { "name": "myelination in peripheral nervous system", "id": "GO:0022011", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022011", "evidence": [ { "database": 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Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052535.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. 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"MVLLPLWVVAAALLGARAAAGRQAGEEQQIQIELPKSRPRPYGLVIPISTNADGSYISNVLSASHQRRSTREVSQSPKQLYFNVTAFGREFHLRLKPNTRLVAPEAVVEWYEDSVETGNGNDAGNSSQTRTATERLWKREPLWTNCAYVGDITDIPGASVAISNCDGLAGMIRTDEDEYFIEPLERGKQMEEEKGRIHMVYRRSAIVQHITDMLPDVHTEESLLGGLGDLSSLYSSVEQQLNETLRRRRHAGDDDYNIEVLLGVDDSVVRFHGKEHVQNYLLTLMNIVNEIYHDESLGVHINVVLVRMIMLGYAKSISLIERGNPSRSLENVCRWAYQQQKSDPNHSEHHDHAIFLTRQDFGPAGMQGYAPVTGMCHPVRSCTLNHEDGFSSAFVVAHETGHVLGMEHDGQGNRCGDETAMGSVMAPLVQAAFHRYHWSRCSGQELKRYIHSYDCLLDDPFEHDWPKLPELPGINYSMDEQCRFDFGVGYKMCTAFRTFDPCKQLWCSHPDNPYFCKTKKGPPLDGTECAPGKWCYKGHCMWKNANQLKQDGNWGPWTKFGSCSRTCGTGVRFRTRQCNNPMPINGGEDCAGVNFEFQLCNTEECPKHFEDFRAQQCQQRNSHFEYQNSKHHWLPYEHPDSNKRCHLYCQSKETGDVAYMKQLAHDGTRCSYKDPYSICVRGECVKVGCDKEIGSNKAEDKCGVCGGDNSHCRTVKGTFTRTPKKLGYLKMFDIPPGARHVFIQEDEASPHFLAIKNQATGHYILNGKGEEARSRSFIDLGVEWEYNIEDDIETLHTDGPLHDAVVVLIIPRENDTRSSLTYKYIIHEDSVPTINSNNVLQEEIDTFEWALKSWSQCSKPCGGGFQYTKYGCRRKSDNKMVHRSFCEASKKPKPIRRMCNLQECTRPLWAADEWEYCTKTCGNSGYQIRTVRCIQPLHDGANRSVHFKYCSGDRPESRRPCNRVPCPAQWKAGPWSECSVTCGEGTETRQIICRAGDHCDGEKPESVRVCKLPPCNDEPCMGDKSIFCQMEVLARYCSIPGYNKLCCESCSKRSSTLPPPFLTEAAETEEEVMFNQSDLHRALVMPTPLVPHYAEFLPGKRGLGRLRFAEADTDTHIAPSNTKPKGAEFPQWRVPLASKTSKLFALLHQPPGNSSSLGPPNDLALVAAVPVVSANNTTVGAPSPSRTSQKSEKQIDKRWPSRPSTVER", "length": 1208, "header": "tr|F1NVD1-1|F1NVD1_CHICK Isoform 1 of ADAM metallopeptidase with thrombospondin type 1 motif 3 OS=Gallus gallus OX=9031 GN=ADAMTS3 PE=4 SV=3 CANONICAL=F1NVD1-1" }, "isoforms": [ { "isoform_ac": "A0A8V0XJP9-1", "url": "https://www.uniprot.org/uniprotkb/F1NVD1/entry#A0A8V0XJP9-1", "sequence": { "sequence": "MVLLPLWVVAAALLGARAAAGRQAGEEQQIQIELPKSRPRPYGLVIPISTNADGSYISNVLSASHQRRSTREVSQSPKQLYFNVTAFGREFHLRLKPNTRLVAPEAVVEWYEDSVETGNGNDAGNSSQTRTATERLWKREPLWTNCAYVGDITDIPGASVAISNCDGLAGMIRTDEDEYFIEPLERGKQMEEEKGRIHMVYRRSAIVQHITDMLPDVHTEESLLGGLGDLSSLYSSVEQQLNETLRRRRHAGDDDYNIEVLLGVDDSVVRFHGKEHVQNYLLTLMNIVNEIYHDESLGVHINVVLVRMIMLGYAKSISLIERGNPSRSLENVCRWAYQQQKSDPNHSEHHDHAIFLTRQDFGPAGMQGYAPVTGMCHPVRSCTLNHEDGFSSAFVVAHETGHVLGMEHDGQGNRCGDETAMGSVMAPLVQAAFHRYHWSRCSGQELKRYIHSYDCLLDDPFEHDWPKLPELPGINYSMDEQCRFDFGVGYKMCTAFRTFDPCKQLWCSHPDNPYFCKTKKGPPLDGTECAPGKWCYKGHCMWKNANQLKQDGNWGPWTKFGSCSRTCGTGVRFRTRQCNNPMPINGGEDCAGVNFEFQLCNTEECPKHFEDFRAQQCQQRNSHFEYQNSKHHWLPYEHPDSNKRCHLYCQSKETGDVAYMKQLAHDGTRCSYKDPYSICVRGECVKVGCDKEIGSNKAEDKCGVCGGDNSHCRTVKGTFTRTPKKLGKHLSKRCQKEFTFLENEIWYLKMFDIPPGARHVFIQEDEASPHFLAIKNQATGHYILNGKGEEARSRSFIDLGVEWEYNIEDDIETLHTDGPLHDAVVVLIIPRENDTRSSLTYKYIIHEDSVPTINSNNVLQEEIDTFEWALKSWSQCSKPCGGGFQYTKYGCRRKSDNKMVHRSFCEASKKPKPIRRMCNLQECTRPLWAADEWEYCTKTCGNSGYQIRTVRCIQPLHDGANRSVHFKYCSGDRPESRRPCNRVPCPAQWKAGPWSECSVTCGEGTETRQIICRAGDHCDGEKPESVRVCKLPPCNDEPCMGDKSIFCQMEVLARYCSIPGYNKLCCESCSKRSSTLPPPFLTEAAETEEEVMFNQSDLHRALVMPTPLVPHYAEFLPGKRGLGRLRFAEADTDTHIAPSNTKPKGAEFPQWRVPLASKTSKLFALLHQPPGNSSSLGPPNDLALVAAVPVVSANNTTVGAPSPSRTSQKSEKQIDKRWPSRPSTVER", "length": 1227, "header": "tr|A0A8V0XJP9-1|F1NVD1_CHICK Computationally mapped isoform of ADAM metallopeptidase with thrombospondin type 1 motif 3 OS=Gallus gallus OX=9031 GN=ADAMTS3 PE=4 SV=1 CANONICAL=F1NVD1-1" }, "locus": { "chromosome": "4", "start_pos": 50109918, "end_pos": 49980377, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010010250.1", "url": "https://www.ensembl.org/id/ENSGALT00010010250.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010005997.1", "url": "https://www.ensembl.org/id/ENSGALP00010005997.1" } ] } }, { "isoform_ac": "A0A8V0XMH6-1", "url": "https://www.uniprot.org/uniprotkb/F1NVD1/entry#A0A8V0XMH6-1", "sequence": { "sequence": "MVLLPLWVVAAALLGARAAAGRQAGEEQQIQIELPKSRPRPYGLVIPISTNADGSYISNVLSASHQRRSTREVSQSPKQLYFNVTAFGREFHLRLKPNTRLVAPEAVVEWYEDSVETGNGNDAGNSSQTRTATERLWKREPLWTNCAYVGDITDIPGASVAISNCDGLAGMIRTDEDEYFIEPLERGKQMEEEKGRIHMVYRRSAIVQHITDMLPDVHTEESLLGGLGDLSSLYSSVEQQLNETLRRRRHAGDDDYNIEVLLGVDDSVVRFHGKEHVQNYLLTLMNIVNEIYHDESLGVHINVVLVRMIMLGYAKSISLIERGNPSRSLENVCRWAYQQQKSDPNHSEHHDHAIFLTRQDFGPAGMQGYAPVTGMCHPVRSCTLNHEDGFSSAFVVAHETGHVLGMEHDGQGNRCGDETAMGSVMAPLVQAAFHRYHWSRCSGQELKRYIHSYDCLLDDPFEHDWPKLPELPGINYSMDEQCRFDFGVGYKMCTAFRTFDPCKQLWCSHPDNPYFCKTKKGPPLDGTECAPGKWCYKGHCMWKNANQLKQDGNWGPWTKFGSCSRTCGTGVRFRTRQCNNPMPINGGEDCAGVNFEFQLCNTEECPKHFEDFRAQQCQQRNSHFEYQNSKHHWLPYEHPDSNKRCHLYCQSKETGDVAYMKQLAHDGTRCSYKDPYSICVRGECVKVGCDKEIGSNKAEDKCGVCGGDNSHCRTVKGTFTRTPKKLGKHLSKRCQKEFTFLENEIWKTRGAFTLPKGARNISLSETKESKNTLGYLKMFDIPPGARHVFIQEDEASPHFLAIKNQATGHYILNGKGEEARSRSFIDLGVEWEYNIEDDIETLHTDGPLHDAVVVLIIPRENDTRSSLTYKYIIHEDSVPTINSNNVLQEEIDTFEWALKSWSQCSKPCGGGFQYTKYGCRRKSDNKMVHRSFCEASKKPKPIRRMCNLQECTRPLWAADEWEYCTKTCGNSGYQIRTVRCIQPLHDGANRSVHFKYCSGDRPESRRPCNRVPCPAQWKAGPWSECSVTCGEGTETRQIICRAGDHCDGEKPESVRVCKLPPCNDEPCMGDKSIFCQMEVLARYCSIPGYNKLCCESCSKRSSTLPPPFLTEAAETEEEVMFNQSDLHRALVMPTPLVPHYAEFLPGKRGLGRLRFAEADTDTHIAPSNTKPKGAEFPQWRVPLASKTSKLFALLHQPPGNSSSLGPPNDLALVAAVPVVSANNTTVGAPSPSRTSQKSEKQIDKRWPSRPSTVER", "length": 1255, "header": "tr|A0A8V0XMH6-1|F1NVD1_CHICK Computationally mapped isoform of ADAM metallopeptidase with thrombospondin type 1 motif 3 OS=Gallus gallus OX=9031 GN=ADAMTS3 PE=4 SV=1 CANONICAL=F1NVD1-1" }, "locus": { "chromosome": "4", "start_pos": 50109918, "end_pos": 49980377, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010010260.1", "url": "https://www.ensembl.org/id/ENSGALT00010010260.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010006003.1", "url": "https://www.ensembl.org/id/ENSGALP00010006003.1" } ] } }, { "isoform_ac": "A0A8V0XP94-1", "url": "https://www.uniprot.org/uniprotkb/F1NVD1/entry#A0A8V0XP94-1", "sequence": { "sequence": "MVLLPLWVVAAALLGARAAAGRQAGEEQQIQIELPKSRPRPYGLVIPISTNADGSYISNVLSASHQRRSTREVSQSPKQLYFNVTAFGREFHLRLKPNTRLVAPEAVVEWYEDSVETGNGNDAGNSSQTRTATERLWKREPLWTNCAYVGDITDIPGASVAISNCDGLAGMIRTDEDEYFIEPLERGKQMEEEKGRIHMVYRRSAIVQHITDMLPDVHTEESLLGGLGDLSSLYSSVEQQLNETLRRRRHAGDDDYNIEVLLGVDDSVVRFHGKEHVQNYLLTLMNIVNEIYHDESLGVHINVVLVRMIMLGYAKSISLIERGNPSRSLENVCRWAYQQQKSDPNHSEHHDHAIFLTRQDFGPAGMQGYAPVTGMCHPVRSCTLNHEDGFSSAFVVAHETGHVLGMEHDGQGNRCGDETAMGSVMAPLVQAAFHRYHWSRCSGQELKRYIHSYDCLLDDPFEHDWPKLPELPGINYSMDEQCRFDFGVGYKMCTAFRTFDPCKQLWCSHPDNPYFCKTKKGPPLDGTECAPGKWCYKGHCMWKNANQLKQDGNWGPWTKFGSCSRTCGTGVRFRTRQCNNPMPINGGEDCAGVNFEFQLCNTEECPKHFEDFRAQQCQQRNSHFEYQNSKHHWLPYEHPDSNKRCHLYCQSKETGDVAYMKQLAHDGTRCSYKDPYSICVRGECVKVGCDKEIGSNKAEDKCGVCGGDNSHCRTVKGTFTRTPKKLGKHLSKRCQKEFTFLENEIWKTRGAFTLPKGARNISLSETKESKNTLAIKNQATGHYILNGKGEEARSRSFIDLGVEWEYNIEDDIETLHTDGPLHDAVVVLIIPRENDTRSSLTYKYIIHEDSVPTINSNNVLQEEIDTFEWALKSWSQCSKPCGGGFQYTKYGCRRKSDNKMVHRSFCEASKKPKPIRRMCNLQECTRPLWAADEWEYCTKTCGNSGYQIRTVRCIQPLHDGANRSVHFKYCSGDRPESRRPCNRVPCPAQWKAGPWSECSVTCGEGTETRQIICRAGDHCDGEKPESVRVCKLPPCNDEPCMGDKSIFCQMEVLARYCSIPGYNKLCCESCSKRSSTLPPPFLTEAAETEEEVMFNQSDLHRALVMPTPLVPHYAEFLPGKRGLGRLRFAEADTDTHIAPSNTKPKGAEFPQWRVPLASKTSKLFALLHQPPGNSSSLGPPNDLALVAAVPVVSANNTTVGAPSPSRTSQKSEKQIDKRWPSRPSTVER", "length": 1228, "header": "tr|A0A8V0XP94-1|F1NVD1_CHICK Computationally mapped isoform of ADAM metallopeptidase with thrombospondin type 1 motif 3 OS=Gallus gallus OX=9031 GN=ADAMTS3 PE=4 SV=1 CANONICAL=F1NVD1-1" }, "locus": { "chromosome": "4", "start_pos": 50109918, "end_pos": 49980377, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010010264.1", "url": "https://www.ensembl.org/id/ENSGALT00010010264.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010006006.1", "url": "https://www.ensembl.org/id/ENSGALP00010006006.1" } ] } }, { "isoform_ac": "F1NVD1-1", "url": "https://www.uniprot.org/uniprotkb/F1NVD1/entry#F1NVD1-1", "sequence": { "sequence": "MVLLPLWVVAAALLGARAAAGRQAGEEQQIQIELPKSRPRPYGLVIPISTNADGSYISNVLSASHQRRSTREVSQSPKQLYFNVTAFGREFHLRLKPNTRLVAPEAVVEWYEDSVETGNGNDAGNSSQTRTATERLWKREPLWTNCAYVGDITDIPGASVAISNCDGLAGMIRTDEDEYFIEPLERGKQMEEEKGRIHMVYRRSAIVQHITDMLPDVHTEESLLGGLGDLSSLYSSVEQQLNETLRRRRHAGDDDYNIEVLLGVDDSVVRFHGKEHVQNYLLTLMNIVNEIYHDESLGVHINVVLVRMIMLGYAKSISLIERGNPSRSLENVCRWAYQQQKSDPNHSEHHDHAIFLTRQDFGPAGMQGYAPVTGMCHPVRSCTLNHEDGFSSAFVVAHETGHVLGMEHDGQGNRCGDETAMGSVMAPLVQAAFHRYHWSRCSGQELKRYIHSYDCLLDDPFEHDWPKLPELPGINYSMDEQCRFDFGVGYKMCTAFRTFDPCKQLWCSHPDNPYFCKTKKGPPLDGTECAPGKWCYKGHCMWKNANQLKQDGNWGPWTKFGSCSRTCGTGVRFRTRQCNNPMPINGGEDCAGVNFEFQLCNTEECPKHFEDFRAQQCQQRNSHFEYQNSKHHWLPYEHPDSNKRCHLYCQSKETGDVAYMKQLAHDGTRCSYKDPYSICVRGECVKVGCDKEIGSNKAEDKCGVCGGDNSHCRTVKGTFTRTPKKLGYLKMFDIPPGARHVFIQEDEASPHFLAIKNQATGHYILNGKGEEARSRSFIDLGVEWEYNIEDDIETLHTDGPLHDAVVVLIIPRENDTRSSLTYKYIIHEDSVPTINSNNVLQEEIDTFEWALKSWSQCSKPCGGGFQYTKYGCRRKSDNKMVHRSFCEASKKPKPIRRMCNLQECTRPLWAADEWEYCTKTCGNSGYQIRTVRCIQPLHDGANRSVHFKYCSGDRPESRRPCNRVPCPAQWKAGPWSECSVTCGEGTETRQIICRAGDHCDGEKPESVRVCKLPPCNDEPCMGDKSIFCQMEVLARYCSIPGYNKLCCESCSKRSSTLPPPFLTEAAETEEEVMFNQSDLHRALVMPTPLVPHYAEFLPGKRGLGRLRFAEADTDTHIAPSNTKPKGAEFPQWRVPLASKTSKLFALLHQPPGNSSSLGPPNDLALVAAVPVVSANNTTVGAPSPSRTSQKSEKQIDKRWPSRPSTVER", "length": 1208, "header": "tr|F1NVD1-1|F1NVD1_CHICK Isoform 1 of ADAM metallopeptidase with thrombospondin type 1 motif 3 OS=Gallus gallus OX=9031 GN=ADAMTS3 PE=4 SV=3 CANONICAL=F1NVD1-1" }, "locus": { "chromosome": "4", "start_pos": 50109918, "end_pos": 49980377, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010010267.1", "url": "https://www.ensembl.org/id/ENSGALT00010010267.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010006009.1", "url": "https://www.ensembl.org/id/ENSGALP00010006009.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:428760", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:428760", "resource": "KEGG Pathway" }, { "id": "R-GGA-1650814", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1650814", "resource": "Reactome", "description": "Collagen biosynthesis and modifying enzymes" }, { "id": "R-GGA-5173214", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5173214", "resource": "Reactome", "description": "O-glycosylation of TSR domain-containing proteins" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287B327-1", "protein_name": "ADAM metallopeptidase with thrombospondin type 1 motif 3", "gene_name": "ADAMTS3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MVLLSLWLIAAALVEVRTSADGQAGNEDMVQIDLPIKRQREYELVTPVSTNFEGHYLSHILSANHKKRSTRDVSSNSEQLFFNITAFGRDFHLRLKPNTQLVAPGAVVEWHETTLVPGNLTEPIHDHQPGRASERIWKTEPLQTNCAYVGDIMDVPGTSVAISNCDGLAGMIKSDNDEYFIEPLERGKQMEEEKGRIHVVYKRSAVEQAPVDMSQDFHYGESNLEGLDDLGTVYSSVDQQLNETMRRRRHAGENDYNIEVLLGVDDSVVRFHGKEHVQNYLLTLMNIVNEIYHDESLGVHINVVLVRMIMLGYAKSISLIERGNPSRSLENVCRWACQQQKSDPNHSEHHDHAIFLTRQDFGPAGMQGYAPVTGMCHPVRSCTLNHEDGFSSAFVVAHETGHVLGMEHDGQGNRCGDETAMGSVMAPLVQAAFHRYHWSRCSGQELKRYIHSYDCLLDDPFEHDWPKLPELPGINYSMDEQCRFDFGVGYKMCTAFRTFDPCKQLWCSHPDNPYFCKTKKGPPLDGTECAAGKWCYKGHCMWKNANQQKQDGNWGSWTKFGSCSRTCGTGVRFRTRQCNNPMPINGGQDCPGVNFEYQLCNTEECQKHFEDFRAQQCQQRNSHFEYQNAKHHWLPYEQPDSKKRCHLYCQSKETGDVAYMKQLVHDGTRCSYKDPYSICVRGECVKVGCDKEIGSNKVEDKCGVCGGDNSHCRTVKGTFTRTPRKLGYLKMFDIPPGARHVLIQEDEASPHVLAIKNQATGHYILNGKGEEAKSKTFIDLGVEWDYNIEDDIETLHTDGPLHDPVIVLIIPQENDTRSSLTYKYIVHEDSAPTINNNNVIQEELDTFEWALKSWSQCSKPCGGGFQYTKYGCRRKSDNKMVHRSFCEANKKPKPIRRMCNIQECTHPLWATEEWEHCTKTCGSSGYQLRTVRCLQPLLDGTNRSVHSKYCLGERPESRRPCNRVPCPAQWKTGPWNECSVTCGEGTEVRQVLCRVGDHCDGEKPESVRACQLPPCNDEPCLGDKSIFCQMEVLARYCSIPGYNKLCCESCGKRSGTLPPPYLPEAAETHDDALFNPSDLPGSLVMPTSLVPHYSEAPAEKKSLSRIFSVGRPNAYAAFRPDSKSDGANLLQRRAQPAESKTPRPASPPTRRGHLTSSPRMSATPFLAASDSIGASSQARTSKKDEKLIDKRRPLRSPTLER", "length": 1201 }, "evidence": [ { "id": "F1NVD1", "url": "https://omabrowser.org/oma/group/F1NVD1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8I5ZMX2-1", "protein_name": "ADAM metallopeptidase with thrombospondin type 1, motif 3", "gene_name": "Adamts3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVFLSLWLIAASLVEVRTSADGQAGAEEMVQIDLPTKRYREYELVTPVSTNLKGHYLSHILSANHKKRSPRDVSSNSEQLFFNVTAFGRDFHLRLRPNTHFIAPGAVVEWHETAPRPGNTTDPRNSRPHRSSSEGGWRSEPLQTSCAYVGDIMDVPGTSVAISNCDGLAGMIKSDNEEYFIEPLERGKQMDEENGRIHIVYKRSAMERAPRDVSEDVYYKESNLEGLDDLGTVYSNIGQQLNETTRRRRHAGENDYNIEVLLGVDDSVVRFHGKEHVQNYLLTLMNIVNEIYHDESLGVHINVVLVRMIMLGYAKSISLIERGNPSRSLENVCRWACQQQKSDPNHAEHHDHAIFLTRQDFGPAGMQGYAPVTGMCHPVRSCTLNHEDGFSSAFVVAHETGHVLGMEHDGQGNRCGDETAMGSVMAPLVQAAFHRYHWSRCSGQELKRYIHSYDCLLDDPFEHDWPKLPELPGINYSMDEQCRFDFGVGYKMCTAFRTFDPCKQLWCSHPDNPYFCKTKKGPPLDGTECAAGKWCYKGHCMWKNANQQKQDGNWGSWTKFGSCSRTCGTGVRFRTRQCNNPTPINGGQDCPGVNFEYQLCNTEECQKHFEDFRAQQCQQRNSHFDYQNTKHHWLPHEHPDSKKRCHLYCQSKETGDVAYMKQLVHDGTRCSYKDPYSICVRGECVKVGCDKEIGSNKVEDKCGVCGGDNSHCRTVKGTFTRTPRKLGKTRGAFVLPKGARNISLAETRETKNVLAIKNQATGHYILNGKGEEAKSRTFIDLGVEWDYNIEDDIETLHTDGPLHDPVIVLIIPQENDTRSSLTYKYIIHEDSVPTINSNNVIQEELDTFEWALKSWSQCSKPCGGGFQYTKYGCRRKSDSKMVHRSFCEVNKKPKPIRRMCNIQECTHPLWAAEAWEHCSRSCGSSGYQLRTVRCLQPLQDGTNRSVHSRYCLGERPESRRPCNRIPCPAQWKTGPWNECSVTCGEGTEVRQVLCRTGDHCDGEKPESVRACQLPPCNDEPCLGDKSIFCQMEVLARYCSIPGYSELCCESCSKRSGTLPPPYLQEAAEIHSDAIFGPSDLPRSLVMPTPFLPYYSGSRADKKSLSSVSSVANPSAYAAFRSSSRASVSFPRKKAQEGGTKTPVSMPPSSSIKTDHLHSSSPGAAAPSPAITDSIGASPQTRTPKKDGKTISRRHPIRSTASER", "length": 1203 }, "evidence": [ { "id": "F1NVD1", "url": "https://omabrowser.org/oma/group/F1NVD1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E1BC50-1", "protein_name": "ADAM metallopeptidase with thrombospondin type 1 motif 3", "gene_name": "ADAMTS3", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MVLLSLWLIAAALVEVKTSADGQAGNEEMVQIDLPIKRQREYELVTPVSTNFEGHYLSHILSANHKKRSTRDVSSNSEQLFFNITAFGRDFHLRLKPNTQLVAPGAVVEWHEASPVPGNITDPINDHQPGSTSERIWKTEPLQTNCAYVGDIMDIPGTSVAISNCDGLAGMIKSDNDEYFIEPLERGKQMEEEKGRIHVVYKRSAVERAPIDMSQDFHYRESDLEGLDDLGTVYSSIDQQLNETMRRRRHAGENDYNIEVLLGVDDSVVRFHGKEHVQNYLLTLMNIVNEIYHDESLGVHINVVLVRMIMLGYAKSISLIERGNPSRSLENVCRWACQQQKSDPNHSEHHDHAIFLTRQDFGPAGMQGYAPVTGMCHPVRSCTLNHEDGFSSAFVVAHETGHVLGMEHDGQGNRCGDETAMGSVMAPLVQAAFHRYHWSRCSGQELKRYIHSYDCLLDDPFEHDWPKLPELPGINYSMDEQCRFDFGVGYKMCTAFRTFDPCKQLWCSHPDNPYFCKTKKGPPLDGTECAAGKWCYKGHCMWKNANQQKQDGNWGSWTKFGSCSRTCGTGVRFRTRQCNNPTPINGGQDCPGVNFEYQLCNTEECQKHFEDFRAQQCQQRNSHFEYQNTKHHWLPYEHPDSKKRCHLYCQSKETGDVAYMKQLVHDGTRCSYKDPYSICVRGECVKVGCDKEIGSNKVEDKCGVCGGDNSHCRTVKGTFTRTPRKLGYLKMFDIPPGARHVLIQEDEASPHVLAIKNQATGHYILNGKGEEAKSKTFIDLGVEWDYNIEDDIETLHTDGPLHDPVIVLIIPQENDTRSSLTYKYIIHEDSAPTINSNNVIQEELDTFEWALKSWSQCSKPCGGGFQYTKYGCRRKSDNKMVHRSFCEVNKKPKPIRRMCNIQECTHPLWAAEEWEHCTKTCGTSGYQLRTVRCLQPLHDGTNRSVHSKYCAGDRPESRRPCNRVPCPAQWKTGPWNECSVTCGEGTEVRQVLCRAGDHCDGEKPESVRACQLPPCNDEPCLGDKSIFCQMEVLARYCSIPGYNKLCCESCSKRSSTLPPPYLSEAAETHDDAIFSDLPGDPSDLPGSLVMPTSLVPYYSETPAEKKKSLSRISSIAGPNEPAAFRSNSKSNGANLSQRQAQPAENATLGPASPPTKSGHLSSSPQLAAARFLAASGSIGASSQARTSKKDEKLIDKRRPLRSSTLER", "length": 1207 }, "evidence": [ { "id": "F1NVD1", "url": "https://omabrowser.org/oma/group/F1NVD1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "E9Q287-1", "protein_name": "ADAM metallopeptidase with thrombospondin type 1 motif 3", "gene_name": "Adamts3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": 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"length": 1204 }, "evidence": [ { "id": "F1NVD1", "url": "https://omabrowser.org/oma/group/F1NVD1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "O15072-1", "protein_name": "A disintegrin and metalloproteinase with thrombospondin motifs 3", "gene_name": "ADAMTS3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": 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"length": 1205 }, "evidence": [ { "id": "F1NVD1", "url": "https://omabrowser.org/oma/group/F1NVD1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "metalloendopeptidase activity", "id": "GO:0004222", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004222", "evidence": [ { "database": "UniProtKB", "id": "F1NVD1", "url": "https://www.uniprot.org/uniprotkb/F1NVD1" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "F1NVD1", "url": "https://www.uniprot.org/uniprotkb/F1NVD1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "F1NVD1", "url": "https://www.uniprot.org/uniprotkb/F1NVD1" } ], "pmid": "" }, { "name": "extracellular matrix organization", "id": "GO:0030198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030198", "evidence": [ { "database": "UniProtKB", "id": "F1NVD1", "url": "https://www.uniprot.org/uniprotkb/F1NVD1" } ], "pmid": "" }, { "name": "protein processing", "id": "GO:0016485", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016485", "evidence": [ { "database": "UniProtKB", "id": "F1NVD1", "url": "https://www.uniprot.org/uniprotkb/F1NVD1" } ], "pmid": "" }, { "name": "vascular endothelial growth factor production", "id": "GO:0010573", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010573", "evidence": [ { "database": "UniProtKB", "id": "F1NVD1", "url": "https://www.uniprot.org/uniprotkb/F1NVD1" } ], "pmid": "" }, { "name": "collagen biosynthetic process", "id": "GO:0032964", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032964", "evidence": [ { "database": "UniProtKB", "id": "F1NVD1", "url": "https://www.uniprot.org/uniprotkb/F1NVD1" } ], "pmid": "" }, { "name": "positive regulation of vascular endothelial growth factor signaling pathway", "id": "GO:1900748", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1900748", "evidence": [ { "database": "UniProtKB", "id": "F1NVD1", "url": "https://www.uniprot.org/uniprotkb/F1NVD1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "F1NVD1", "url": "https://www.uniprot.org/uniprotkb/F1NVD1" } ], "pmid": "" }, { "name": "extracellular matrix", "id": "GO:0031012", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031012", "evidence": [ { "database": "UniProtKB", "id": "F1NVD1", "url": "https://www.uniprot.org/uniprotkb/F1NVD1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1075, "end_pos": 1077, "annotation": 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##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BI395075.1 and BE187702.1. On May 5, 2013 this sequence version replaced XP_429886.2.", "evidence": [ { "database": "RefSeq", "id": "NP_001264950", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264950" } ] }, { "annotation": "Shared alpha chain of heterodimeric glycoprotein hormones. 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gallus OX=9031 GN=CGA PE=3 SV=1 CANONICAL=F1NJD3-1" }, "locus": { "chromosome": "3", "start_pos": 76297074, "end_pos": 76271815, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010008884.1", "url": "https://www.ensembl.org/id/ENSGALT00010008884.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010005228.1", "url": "https://www.ensembl.org/id/ENSGALP00010005228.1" } ] } }, { "isoform_ac": "F1NJD3-1", "url": "https://www.uniprot.org/uniprotkb/F1NJD3/entry#F1NJD3-1", "sequence": { "sequence": "MDCYRKYAAVTLTILSVFLHLLHTFPDGEFLMQGCPECKLGENRFFSKPGAPIYQCTGCCFSRAYPTPMRSKKTMLVPKNITSEATCCVAKAFTKITLKDNVKIENHTDCHCSTCYYHKS", "length": 120, "header": "tr|F1NJD3-1|F1NJD3_CHICK Isoform 1 of Glycoprotein hormones alpha chain OS=Gallus gallus OX=9031 GN=CGA PE=3 SV=2 CANONICAL=F1NJD3-1" }, "locus": { "chromosome": "3", "start_pos": 76297074, "end_pos": 76293759, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010008882.1", "url": "https://www.ensembl.org/id/ENSGALT00010008882.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010005226.1", "url": "https://www.ensembl.org/id/ENSGALP00010005226.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 67, "start_aa": "Thr", "end_pos": 67, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr67", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:421829", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:421829", "resource": "KEGG Pathway" }, { "id": "R-GGA-209822", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-209822", "resource": "Reactome", "description": "Glycoprotein hormones" }, { "id": "R-GGA-209968", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-209968", "resource": "Reactome", "description": "Thyroxine biosynthesis" }, { "id": "R-GGA-375281", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-375281", "resource": "Reactome", "description": "Hormone ligand-binding receptors" }, { "id": "R-GGA-418555", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-418555", "resource": "Reactome", "description": "G alpha (s) signalling events" } ], "orthologs": [ { "uniprot_canonical_ac": "P01215-1", "protein_name": "Glycoprotein hormones alpha chain", "gene_name": "CGA", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDYYRKYAAIFLVTLSVFLHVLHSAPDVQDCPECTLQENPFFSQPGAPILQCMGCCFSRAYPTPLRSKKTMLVQKNVTSESTCCVAKSYNRVTVMGGFKVENHTACHCSTCYYHKS", "length": 116 }, "evidence": [ { "id": "F1NJD3", "url": "https://omabrowser.org/oma/group/F1NJD3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P01216-1", "protein_name": "Glycoprotein hormones alpha chain", "gene_name": "Cga", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDYYRKYAAVILVMLSMFLHILHSLPDGDFIIQGCPECKLKENKYFSKLGAPIYQCMGCCFSRAYPTPARSKKTMLVPKNITSEATCCVAKAFTKATVMGNARVENHTECHCSTCYYHKS", "length": 120 }, "evidence": [ { "id": "F1NJD3", "url": "https://omabrowser.org/oma/group/F1NJD3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P01217-1", "protein_name": "Glycoprotein hormones alpha chain", "gene_name": "CGA", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MDYYRKYAAVILAILSLFLQILHSFPDGEFTMQGCPECKLKENKYFSKPDAPIYQCMGCCFSRAYPTPARSKKTMLVPKNITSEATCCVAKAFTKATVMGNVRVENHTECHCSTCYYHKS", "length": 120 }, "evidence": [ { "id": 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"https://omabrowser.org/oma/group/F1NJD3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "F1NJD3", "url": "https://www.uniprot.org/uniprotkb/F1NJD3" } ], "pmid": "" }, { "name": "follicle-stimulating hormone complex", "id": "GO:0016914", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016914", "evidence": [ { "database": "UniProtKB", "id": "F1NJD3", "url": "https://www.uniprot.org/uniprotkb/F1NJD3" } ], "pmid": "" }, { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "F1NJD3", "url": "https://www.uniprot.org/uniprotkb/F1NJD3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "G protein-coupled receptor signaling pathway", "id": "GO:0007186", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007186", "evidence": [ { "database": "UniProtKB", "id": "F1NJD3", "url": "https://www.uniprot.org/uniprotkb/F1NJD3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "follicle-stimulating hormone activity", "id": "GO:0016913", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016913", "evidence": [ { "database": "UniProtKB", "id": "F1NJD3", "url": "https://www.uniprot.org/uniprotkb/F1NJD3" } ], "pmid": "" }, { "name": "hormone activity", "id": "GO:0005179", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005179", "evidence": [ { "database": "UniProtKB", "id": "F1NJD3", "url": "https://www.uniprot.org/uniprotkb/F1NJD3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 106, "end_pos": 108, "annotation": "n_glycosylation_sequon" }, { "start_pos": 80, "end_pos": 82, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 67 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 106, "end_pos": 108 }, { "start_pos": 80, "end_pos": 82 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", 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"comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1NMQ3-1", "uniprot_ac": "F1NMQ3", "uniprot_id": "F1NMQ3_CHICK", "mass": { "chemical_mass": 19103.0, "monoisotopic_mass": 19103.0 }, "refseq": { "ac": "NP_001006253", "name": "PEST proteolytic signal-containing nuclear protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006253" }, "gene_names": [ { "name": "PCNP", "type": "recommended", "evidence": [ { "id": "F1NMQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NMQ3" } ] }, { "name": "PCNP", "type": "synonym", "evidence": [ { "id": "NP_001006253", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006253" } ] } ], "protein_names": [ { "name": "PEST proteolytic signal-containing nuclear protein", "type": "recommended", "evidence": [ { "id": "F1NMQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NMQ3/entry#names_and_taxonomy" } ] }, { "name": "PEST proteolytic signal-containing nuclear protein", "type": "synonym", "evidence": [ { "id": "NP_001006253", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006253" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ719633.1, HAEK01009869.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000019.1. On Sep 23, 2021 this sequence version replaced NP_001006253.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001006253", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006253" } ] }, { "annotation": "May be involved in cell cycle regulation.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0XP59", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XP59#function" }, { "database": "UniProtKB", "id": "ARBA00002646", "url": "https://www.uniprot.org/uniprotkb/ARBA00002646#function" }, { "database": "UniProtKB", "id": "F1NMQ3", "url": "https://www.uniprot.org/uniprotkb/F1NMQ3#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NMQ3", "url": "https://www.uniprot.org/uniprotkb/F1NMQ3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PCNP", "url": "https://www.uniprot.org/uniprotkb/F1NMQ3", "locus": { "chromosome": "1", "start_pos": 85583906, "end_pos": 85573118, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010006039", "url": "https://www.ensembl.org/id/ENSGALG00010006039" } ] } } ], "crossref": [ { "id": "F1NMQ3", "url": "https://alphafold.ebi.ac.uk/entry/F1NMQ3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000015330", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000015330", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "418398", "url": "https://www.ncbi.nlm.nih.gov/gene/418398", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR029169", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029169", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:418398", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418398", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0XP59", "url": "https://www.orthodb.org/?gene=A0A8V0XP59", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NMQ3", "url": "https://www.orthodb.org/?gene=F1NMQ3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16523", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16523", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16523:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16523:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15473", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15473", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001006253", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006253", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0XP59", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XP59", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XP59-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XP59-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NMQ3", "url": "https://www.uniprot.org/uniprotkb/F1NMQ3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NMQ3-1", "url": "https://www.uniprot.org/uniprotkb/F1NMQ3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MADGRAEGEKARRPPPAGGPEEEAEKPVKTKTVSSSNGGESSSRSAEKRAANEEAEDFTTKPAPAKMSKFGFSIGSQTSKKASAISIKLAANKPKEPVPTLAPKTLSVAAAFNEDEDSEPEEMPPEAKMRMKNIGRDTPTSAGPNSFNKGKHGFSDNQKLWERNIKSHLGNIHDQENN", "length": 178, "header": "tr|F1NMQ3-1|F1NMQ3_CHICK Isoform 1 of PEST proteolytic signal-containing nuclear protein OS=Gallus gallus OX=9031 GN=PCNP PE=1 SV=1 CANONICAL=F1NMQ3-1" }, "isoforms": [ { "isoform_ac": "A0A8V0XP59-1", "url": "https://www.uniprot.org/uniprotkb/F1NMQ3/entry#A0A8V0XP59-1", "sequence": { "sequence": "MTLAQSAGRYSARAGSGPHPPEVHHTGASWSSSRLPLTVSASGTPLRLSMAMGGAGGGGAATSRRACAAREAEAGENGGRQSGGGEGEAAAARRSNGGESSSRSAEKRAANEEAEDFTTKPAPAKMSKFGFSIGSQTSKKASAISIKLAANKPKEPVPTLAPKTLSVAAAFNEDEDSEPEEMPPEAKMRMKNIGRDTPTSAGPNSFNKGKHGFSDNQKLWERNIKSHLGNIHDQENN", "length": 237, "header": "tr|A0A8V0XP59-1|F1NMQ3_CHICK Computationally mapped isoform of PEST proteolytic signal-containing nuclear protein OS=Gallus gallus OX=9031 GN=PCNP PE=1 SV=1 CANONICAL=F1NMQ3-1" }, "locus": { "chromosome": "1", "start_pos": 85581524, "end_pos": 85573317, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010014457.1", "url": "https://www.ensembl.org/id/ENSGALT00010014457.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010008484.1", "url": "https://www.ensembl.org/id/ENSGALP00010008484.1" } ] } }, { "isoform_ac": "F1NMQ3-1", "url": "https://www.uniprot.org/uniprotkb/F1NMQ3/entry#F1NMQ3-1", "sequence": { "sequence": "MADGRAEGEKARRPPPAGGPEEEAEKPVKTKTVSSSNGGESSSRSAEKRAANEEAEDFTTKPAPAKMSKFGFSIGSQTSKKASAISIKLAANKPKEPVPTLAPKTLSVAAAFNEDEDSEPEEMPPEAKMRMKNIGRDTPTSAGPNSFNKGKHGFSDNQKLWERNIKSHLGNIHDQENN", "length": 178, "header": "tr|F1NMQ3-1|F1NMQ3_CHICK Isoform 1 of PEST proteolytic signal-containing nuclear protein OS=Gallus gallus OX=9031 GN=PCNP PE=1 SV=1 CANONICAL=F1NMQ3-1" }, "locus": { "chromosome": "1", "start_pos": 85581524, "end_pos": 85573546, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010014453.1", "url": "https://www.ensembl.org/id/ENSGALT00010014453.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010008483.1", "url": "https://www.ensembl.org/id/ENSGALP00010008483.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:418398", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418398", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1NMQ3", "url": "https://www.uniprot.org/uniprotkb/F1NMQ3" } ], "pmid": "" }, { "name": "nuclear body", "id": "GO:0016604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016604", "evidence": [ { "database": "UniProtKB", "id": "F1NMQ3", "url": "https://www.uniprot.org/uniprotkb/F1NMQ3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "proteasome-mediated ubiquitin-dependent protein catabolic process", "id": "GO:0043161", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043161", "evidence": [ { "database": "UniProtKB", "id": "F1NMQ3", "url": "https://www.uniprot.org/uniprotkb/F1NMQ3" } ], "pmid": "" }, { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "F1NMQ3", "url": "https://www.uniprot.org/uniprotkb/F1NMQ3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1P1R3-1", "uniprot_ac": "F1P1R3", "uniprot_id": "F1P1R3_CHICK", "mass": { "chemical_mass": 24007.0, "monoisotopic_mass": 24007.0 }, "refseq": { "ac": "NP_001264835", "name": "26S proteasome non-ATPase regulatory subunit 10", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264835" }, "gene_names": [ { "name": "PSMD10", "type": "recommended", "evidence": [ { "id": "F1P1R3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P1R3" } ] }, { "name": "PSMD10", "type": "synonym", "evidence": [ { "id": "NP_001264835", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264835" } ] } ], "protein_names": [ { "name": "26S proteasome non-ATPase regulatory subunit 10", "type": "recommended", "evidence": [ { "id": "F1P1R3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P1R3/entry#names_and_taxonomy" } ] }, { "name": "26S proteasome non-ATPase regulatory subunit 10", "type": "synonym", "evidence": [ { "id": "NP_001264835", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264835" } ] }, { "name": "26S proteasome regulatory subunit p28", "type": "synonym", "evidence": [ { "id": "F1P1R3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P1R3/entry#names_and_taxonomy" } ] }, { "name": "Gankyrin", "type": "synonym", "evidence": [ { "id": "F1P1R3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P1R3/entry#names_and_taxonomy" } ] }, { "name": "proteasome (prosome, macropain) 26S subunit, non-ATPase, 10", "type": "synonym", "evidence": [ { "id": "NP_001264835", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264835" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: HAEK01110859.1, BX930932.2 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000071.1. On Apr 28, 2013 this sequence version replaced XP_420323.3.", "evidence": [ { "database": "RefSeq", "id": "NP_001264835", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264835" } ] }, { "annotation": "Acts as a chaperone during the assembly of the 26S proteasome, specifically of the PA700/19S regulatory complex (RC). In the initial step of the base subcomplex assembly is part of an intermediate PSMD10:PSMC4:PSMC5:PAAF1 module which probably assembles with a PSMD5:PSMC2:PSMC1:PSMD2 module. Independently of the proteasome, regulates EGF-induced AKT activation through inhibition of the RHOA/ROCK/PTEN pathway, leading to prolonged AKT activation. Plays an important role in RAS-induced tumorigenesis.", "evidence": [ { "database": "UniProtKB", "id": "F1P1R3", "url": "https://www.uniprot.org/uniprotkb/F1P1R3#function" }, { "database": "UniProtKB", "id": "ARBA00059111", "url": "https://www.uniprot.org/uniprotkb/ARBA00059111#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1P1R3", "url": "https://www.uniprot.org/uniprotkb/F1P1R3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PSMD10", "url": "https://www.uniprot.org/uniprotkb/F1P1R3", "locus": { "chromosome": "4", "start_pos": 14077488, "end_pos": 14073047, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010015795", "url": "https://www.ensembl.org/id/ENSGALG00010015795" } ] } } ], "crossref": [ { "id": "F1P1R3", "url": "https://alphafold.ebi.ac.uk/entry/F1P1R3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000008287", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000008287", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "422351", "url": "https://www.ncbi.nlm.nih.gov/gene/422351", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036770", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036770", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:422351", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422351", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WAVAYNR", "url": "https://omabrowser.org/oma/group/WAVAYNR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5NUF7", "url": "https://www.orthodb.org/?gene=A0A1D5NUF7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1P1R3", "url": "https://www.orthodb.org/?gene=F1P1R3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24173", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24173", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24173:SF74", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24173:SF74", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00023", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00023", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12796", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12796", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13637", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13637", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001264835", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264835", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5NUF7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NUF7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5NUF7-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NUF7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1P1R3", "url": "https://www.uniprot.org/uniprotkb/F1P1R3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1P1R3-1", "url": "https://www.uniprot.org/uniprotkb/F1P1R3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEGAVSNVEVCNLAYAGRLEELRAQLLRDRALATATDQDSRTALHWACSAGHAAVADLLLGLGVPVGDKDDAGWTPLHIAASAGRDEIVKALIDKGAPINAVNQNGCTPLHYAASKNKQEIAIMLLENGADPDATDHFESTPLHRAAAKGNLKMIQILLRHNASVNIQDSEGNTPLHLACDEERVDEAKLLVSHGASIHTENKEELTPLKVAKGGLGAILKRMVEG", "length": 226, "header": "tr|F1P1R3-1|F1P1R3_CHICK Isoform 1 of 26S proteasome non-ATPase regulatory subunit 10 OS=Gallus gallus OX=9031 GN=PSMD10 PE=1 SV=3 CANONICAL=F1P1R3-1" }, "isoforms": [ { "isoform_ac": "A0A1D5NUF7-1", "url": "https://www.uniprot.org/uniprotkb/F1P1R3/entry#A0A1D5NUF7-1", "sequence": { "sequence": "MEGAVSNVEVCNLAYAGRLEELRAQLLRDRALATATDQAGWTPLHIAASAGRDEIVKALIDKGAPINAVNQNGCTPLHYAASKNKQEIAIMLLENGADPDATDHFESTPLHRAAAKGNLKMIQILLRHNASVNIQDSEGNTPLHLACDEERVDEAKLLVSHGASIHTENKEELTPLKVAKGGLGAILKRMVEG", "length": 193, "header": "tr|A0A1D5NUF7-1|A0A1D5NUF7_CHICK Computationally mapped isoform of Proteasome 26S subunit, non-ATPase 10 OS=Gallus gallus OX=9031 GN=PSMD10 PE=1 SV=1 CANONICAL=F1P1R3-1" }, "locus": { "chromosome": "4", "start_pos": 14075684, "end_pos": 14073081, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010038021.1", "url": "https://www.ensembl.org/id/ENSGALT00010038021.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021936.1", "url": "https://www.ensembl.org/id/ENSGALP00010021936.1" } ] } }, { "isoform_ac": "F1P1R3-1", "url": "https://www.uniprot.org/uniprotkb/F1P1R3/entry#F1P1R3-1", "sequence": { "sequence": "MEGAVSNVEVCNLAYAGRLEELRAQLLRDRALATATDQDSRTALHWACSAGHAAVADLLLGLGVPVGDKDDAGWTPLHIAASAGRDEIVKALIDKGAPINAVNQNGCTPLHYAASKNKQEIAIMLLENGADPDATDHFESTPLHRAAAKGNLKMIQILLRHNASVNIQDSEGNTPLHLACDEERVDEAKLLVSHGASIHTENKEELTPLKVAKGGLGAILKRMVEG", "length": 226, "header": "tr|F1P1R3-1|F1P1R3_CHICK Isoform 1 of 26S proteasome non-ATPase regulatory subunit 10 OS=Gallus gallus OX=9031 GN=PSMD10 PE=1 SV=3 CANONICAL=F1P1R3-1" }, "locus": { "chromosome": "4", "start_pos": 14075684, "end_pos": 14073081, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010038019.1", "url": "https://www.ensembl.org/id/ENSGALT00010038019.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021934.1", "url": "https://www.ensembl.org/id/ENSGALP00010021934.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:422351", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422351", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A061HY35-1", "protein_name": "26S proteasome non-ATPase regulatory subunit 10", "gene_name": "Psmd10", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MEGCVSNLMVCNLAYTGKLDELKESILADRTLATRTDQDNRTALHWACSAGHTEIVEFLLQLGVPVNDKDDAGWSPLHIAASAGRDEIVKALLVKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPDAKDHYEATAMHRAAAKGNLKMVHILLFYKASTNIQDTEGNTPLHLACDEERVEEAKLLVTQGASIYIENKEEKTPLQVAKGGLGLILKRIVES", "length": 226 }, "evidence": [ { "id": "F1P1R3", "url": "https://omabrowser.org/oma/group/F1P1R3/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A3S5ZP61-1", "protein_name": "26S proteasome non-ATPase regulatory subunit 10", "gene_name": "PSMD10", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGKAKEEERMVIGGALRALLISARSLRSEEVVDLAAPRSWESEMEGCVSNLMICNLAYSGKLEELKERILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLGVPVNDKDDAGWSPLHIAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPDAKDHYEATAMHRAAAKGNLKMIHILLYYKASTNIQDTEGNTPLHLACDEERVEEAKLLVSQGASIYIENKEEKTPLQVAKGGLGLILKRMVES", "length": 269 }, "evidence": [ { "id": "F1P1R3", "url": "https://omabrowser.org/oma/group/F1P1R3/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A4X1W5E4-1", "protein_name": "26S proteasome non-ATPase regulatory subunit 10", "gene_name": "PSMD10", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEGCVSNLMVCNLAYSGKLEELKERILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLGVPVNDKDDAGWSPLHIAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPDAKDHYEATAMHRAAAKGNLKMIHILLYYKASTNIQDTEGNTPLHLACDEERVEEAKLLVSQGASIYIENKEEKTPLQVAKGGLGLILKRMVES", "length": 226 }, "evidence": [ { "id": "F1P1R3", "url": "https://omabrowser.org/oma/group/F1P1R3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "O75832-1", "protein_name": "26S proteasome non-ATPase regulatory subunit 10", "gene_name": "PSMD10", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEGCVSNLMVCNLAYSGKLEELKESILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLGVPVNDKDDAGWSPLHIAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPDAKDHYEATAMHRAAAKGNLKMIHILLYYKASTNIQDTEGNTPLHLACDEERVEEAKLLVSQGASIYIENKEEKTPLQVAKGGLGLILKRMVEG", "length": 226 }, "evidence": [ { "id": "F1P1R3", "url": "https://omabrowser.org/oma/group/F1P1R3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P50086-1", "protein_name": "Probable 26S proteasome regulatory subunit p28", "gene_name": "NAS6", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSNYPLHQACMENEFFKVQELLHSKPSLLLQKDQDGRIPLHWSVSFQAHEITSFLLSKMENVNLDDYPDDSGWTPFHIACSVGNLEVVKSLYDRPLKPDLNKITNQGVTCLHLAVGKKWFEVSQFLIENGASVRIKDKFNQIPLHRAASVGSLKLIELLCGLGKSAVNWQDKQGWTPLFHALAEGHGDAAVLLVEKYGAEYDLVDNKGAKAEDVALNEQVKKFFLNNV", "length": 228 }, "evidence": [ { "id": "F1P1R3", "url": "https://omabrowser.org/oma/group/F1P1R3/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q54HW1-1", "protein_name": "26S proteasome non-ATPase regulatory subunit 10", "gene_name": "psmD10", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSGTKFRTGGTKEDDLLEFVKVGKLLEVKDLIENQGVKADCKDEDERTPLHWAAAKGQISVAQYLMDNCKCSPNTNDDGGWTPLTSATSAGHTHMVKLLLEFGADPNTVNDSKRTPLHYASSKGRSDIVDLLLTHGAKNRKDDTGSAPIHRASSNGSVATVERLLKGEANINSTNNEGDTPLHIAAEYNHEDVVECLLKHGADTTIENKDSKTPIDMSSSQTIKYLIKEFKK", "length": 232 }, "evidence": [ { "id": "F1P1R3", "url": "https://omabrowser.org/oma/group/F1P1R3/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q9Z2X2-1", "protein_name": "26S proteasome non-ATPase regulatory subunit 10", "gene_name": "Psmd10", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEGCVSNIMICNLAYSGKLDELKERILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLGVPVNDKDDAGWSPLHIAASAGRDEIVKALLVKGAHVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPDAKDHYDATAMHRAAAKGNLKMVHILLFYKASTNIQDTEGNTPLHLACDEERVEEAKFLVTQGASIYIENKEEKTPLQVAKGGLGLILKRLAESEEASM", "length": 231 }, "evidence": [ { "id": "F1P1R3", "url": "https://omabrowser.org/oma/group/F1P1R3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9Z2X3-1", "protein_name": "26S proteasome non-ATPase regulatory subunit 10", "gene_name": "Psmd10", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEGCVSNLMVCNLAYNGKLDELKESILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLGVPVNEKDDAGWSPLHIAASAGRDEIVKALLIKGAQVNAVNQNGCTALHYAASKNRHEIAVMLLEGGANPDAKNHYDATAMHRAAAKGNLKMVHILLFYKASTNIQDTEGNTPLHLACDEERVEEAKLLVTQGASIYIENKEEKTPLQVAKGGLGLILKRIAESEEASM", "length": 231 }, "evidence": [ { "id": "F1P1R3", "url": "https://omabrowser.org/oma/group/F1P1R3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "proteasome regulatory particle, base subcomplex", "id": "GO:0008540", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008540", "evidence": [ { "database": "UniProtKB", "id": "F1P1R3", "url": "https://www.uniprot.org/uniprotkb/F1P1R3" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1P1R3", "url": "https://www.uniprot.org/uniprotkb/F1P1R3" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F1P1R3", "url": "https://www.uniprot.org/uniprotkb/F1P1R3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 9, "go_terms": [ { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "F1P1R3", "url": "https://www.uniprot.org/uniprotkb/F1P1R3" } ], "pmid": "" }, { "name": "positive regulation of cell growth", "id": "GO:0030307", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030307", "evidence": [ { "database": "UniProtKB", "id": "F1P1R3", "url": "https://www.uniprot.org/uniprotkb/F1P1R3" } ], "pmid": "" }, { "name": "apoptotic process", "id": "GO:0006915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006915", "evidence": [ { "database": "UniProtKB", "id": "F1P1R3", "url": "https://www.uniprot.org/uniprotkb/F1P1R3" } ], "pmid": "" }, { "name": "positive regulation of protein ubiquitination", "id": "GO:0031398", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031398", "evidence": [ { "database": "UniProtKB", "id": "F1P1R3", "url": "https://www.uniprot.org/uniprotkb/F1P1R3" } ], "pmid": "" }, { "name": "positive regulation of proteasomal ubiquitin-dependent protein catabolic process", "id": "GO:0032436", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032436", "evidence": [ { "database": "UniProtKB", "id": "F1P1R3", "url": "https://www.uniprot.org/uniprotkb/F1P1R3" } ], "pmid": "" }, { "name": "negative regulation of release of cytochrome c from mitochondria", "id": "GO:0090201", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090201", "evidence": [ { "database": "UniProtKB", "id": "F1P1R3", "url": "https://www.uniprot.org/uniprotkb/F1P1R3" } ], "pmid": "" }, { "name": "negative regulation of MAPK cascade", "id": "GO:0043409", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043409", "evidence": [ { "database": "UniProtKB", "id": "F1P1R3", "url": "https://www.uniprot.org/uniprotkb/F1P1R3" } ], "pmid": "" }, { "name": "negative regulation of DNA damage response, signal transduction by p53 class mediator", "id": "GO:0043518", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043518", "evidence": [ { "database": "UniProtKB", "id": "F1P1R3", "url": "https://www.uniprot.org/uniprotkb/F1P1R3" } ], "pmid": "" }, { "name": "proteasome regulatory particle assembly", "id": "GO:0070682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070682", "evidence": [ { "database": "UniProtKB", "id": "F1P1R3", "url": "https://www.uniprot.org/uniprotkb/F1P1R3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 162, "end_pos": 164, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1P1R3-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 226, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1P1R3-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1P1R3" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 162, "end_pos": 164 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": 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} ], "function": [ { "annotation": "Phospholipase that may play a role in phospholipids remodeling. May selectively cleave myristate (C14)-containing phosphatidylcholines through its predominant phospholipase 1 activity, cleaving preferentially acyl groups in sn1 position. In parallel, may have a minor phospholipase 2 activity acting on acyl groups in position sn2. In addition to (C14)-containing phosphatidylcholines, may also act on other medium-chain-containing and oxidatively truncated phospholipids.", "evidence": [ { "database": "UniProtKB", "id": "F1NTP8", "url": "https://www.uniprot.org/uniprotkb/F1NTP8#function" }, { "database": "UniProtKB", "id": "ARBA00059841", "url": "https://www.uniprot.org/uniprotkb/ARBA00059841#function" }, { "database": "UniProtKB", "id": "A0A1D5P3N2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P3N2#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NTP8", "url": "https://www.uniprot.org/uniprotkb/F1NTP8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ABHD3", "url": "https://www.uniprot.org/uniprotkb/F1NTP8", "locus": { "chromosome": "2", "start_pos": 102062376, "end_pos": 102084463, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010005109", "url": "https://www.ensembl.org/id/ENSGALG00010005109" } ] } } ], "crossref": [ { "id": "F1NTP8", "url": "https://alphafold.ebi.ac.uk/entry/F1NTP8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000014938", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000014938", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "421068", "url": "https://www.ncbi.nlm.nih.gov/gene/421068", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000073", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000073", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000952", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000952", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012020", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012020", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029058", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029058", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050960", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050960", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5P3N2", "url": "https://www.orthodb.org/?gene=A0A1D5P3N2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NTP8", "url": "https://www.orthodb.org/?gene=F1NTP8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10794", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10794", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10794:SF50", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10794:SF50", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00561", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00561", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-1483191", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1483191", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "15801", "url": "https://www.rhea-db.org/rhea/15801", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "18689", "url": "https://www.rhea-db.org/rhea/18689", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "40479", "url": "https://www.rhea-db.org/rhea/40479", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "40483", "url": "https://www.rhea-db.org/rhea/40483", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "41159", "url": "https://www.rhea-db.org/rhea/41159", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "41179", "url": "https://www.rhea-db.org/rhea/41179", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "41388", "url": "https://www.rhea-db.org/rhea/41388", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "54388", "url": "https://www.rhea-db.org/rhea/54388", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "54392", "url": "https://www.rhea-db.org/rhea/54392", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "54396", "url": "https://www.rhea-db.org/rhea/54396", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "54400", "url": "https://www.rhea-db.org/rhea/54400", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "54404", "url": "https://www.rhea-db.org/rhea/54404", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "54408", "url": "https://www.rhea-db.org/rhea/54408", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "54456", "url": "https://www.rhea-db.org/rhea/54456", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "54460", "url": "https://www.rhea-db.org/rhea/54460", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "54464", "url": "https://www.rhea-db.org/rhea/54464", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "54468", "url": "https://www.rhea-db.org/rhea/54468", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "54472", "url": "https://www.rhea-db.org/rhea/54472", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "54552", "url": "https://www.rhea-db.org/rhea/54552", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A1D5P3N2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P3N2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5P3N2-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P3N2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NTP8", "url": "https://www.uniprot.org/uniprotkb/F1NTP8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NTP8-1", "url": "https://www.uniprot.org/uniprotkb/F1NTP8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDWQVLTRELSLYLESQVRVGLFGSGVGLSLVLGFGVAYACYYLSSIAKKPQLVSSNERFCRFLEEYCPVVTETYYPTIWCWEGRVQTLLRPFITSRPQVQYRNELIRTADGGQISLDWFDNNDSLYYPDASTRPTVLLLPGLTGTSKESYILHMIHQSETLGYRCVVFNNRGIAGEELLTPRTYCAANTEDLEAVIHHIHNLHPSAPFMAAGVSMGGMLLLNYLGKTGRDTPLMAAAIFSAGWNVFESVESLEKPLNWLLFNYYLTTCLQSSISRHRQMLEKLFDMDLVMKARTVREFDKQFTSVMFGYRTIDDYYEDASPCRKLKSVGIPVLCLNSVDDVFSPGHAIPVETAKQNANVALVLTSCGGHIGFLEGIWPRKCTYMDRVFKQFVQAVFEHGNKIFSM", "length": 406, "header": "tr|F1NTP8-1|F1NTP8_CHICK Isoform 1 of Phospholipase ABHD3 OS=Gallus gallus OX=9031 GN=ABHD3 PE=3 SV=3 CANONICAL=F1NTP8-1" }, "isoforms": [ { "isoform_ac": "A0A1D5P3N2-1", "url": "https://www.uniprot.org/uniprotkb/F1NTP8/entry#A0A1D5P3N2-1", "sequence": { "sequence": "MMISTVIGIEAVRNISACRALLEKPQLVSSNERFCRFLEEYCPVVTETYYPTIWCWEGRVQTLLRPFITSRPQVQYRNELIRTADGGQISLDWFDNNDSLYYPDASTRPTVLLLPGLTGTSKESYILHMIHQSETLGYRCVVFNNRGIAGEELLTPRTYCAANTEDLEAVIHHIHNLHPSAPFMAAGVSMGGMLLLNYLGKTGRDTPLMAAAIFSAGWNVFESVESLEKPLNWLLFNYYLTTCLQSSISRHRQMLEKLFDMDLVMKARTVREFDKQFTSVMFGYRTIDDYYEDASPCRKLKSVGIPVLCLNSVDDVFSPGHAIPVETAKQNANVALVLTSCGGHIGFLEGIWPRKCTYMDRVFKQFVQAVFEHGNKIFSM", "length": 380, "header": "tr|A0A1D5P3N2-1|A0A1D5P3N2_CHICK Computationally mapped isoform of Phospholipase ABHD3 OS=Gallus gallus OX=9031 GN=ABHD3 PE=3 SV=2 CANONICAL=F1NTP8-1" }, "locus": { "chromosome": "2", "start_pos": 102083294, "end_pos": 102064267, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010012016.1", "url": "https://www.ensembl.org/id/ENSGALT00010012016.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010006709.1", "url": "https://www.ensembl.org/id/ENSGALP00010006709.1" } ] } }, { "isoform_ac": "F1NTP8-1", "url": "https://www.uniprot.org/uniprotkb/F1NTP8/entry#F1NTP8-1", "sequence": { "sequence": "MDWQVLTRELSLYLESQVRVGLFGSGVGLSLVLGFGVAYACYYLSSIAKKPQLVSSNERFCRFLEEYCPVVTETYYPTIWCWEGRVQTLLRPFITSRPQVQYRNELIRTADGGQISLDWFDNNDSLYYPDASTRPTVLLLPGLTGTSKESYILHMIHQSETLGYRCVVFNNRGIAGEELLTPRTYCAANTEDLEAVIHHIHNLHPSAPFMAAGVSMGGMLLLNYLGKTGRDTPLMAAAIFSAGWNVFESVESLEKPLNWLLFNYYLTTCLQSSISRHRQMLEKLFDMDLVMKARTVREFDKQFTSVMFGYRTIDDYYEDASPCRKLKSVGIPVLCLNSVDDVFSPGHAIPVETAKQNANVALVLTSCGGHIGFLEGIWPRKCTYMDRVFKQFVQAVFEHGNKIFSM", "length": 406, "header": "tr|F1NTP8-1|F1NTP8_CHICK Isoform 1 of Phospholipase ABHD3 OS=Gallus gallus OX=9031 GN=ABHD3 PE=3 SV=3 CANONICAL=F1NTP8-1" }, "locus": { "chromosome": "2", "start_pos": 102084365, "end_pos": 102064267, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010012018.1", "url": "https://www.ensembl.org/id/ENSGALT00010012018.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010006711.1", "url": "https://www.ensembl.org/id/ENSGALP00010006711.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "R-GGA-1483191", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1483191", "resource": "Reactome", "description": "Synthesis of PC" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "F1NTP8", "url": "https://www.uniprot.org/uniprotkb/F1NTP8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "phospholipase A2 activity", "id": "GO:0004623", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004623", "evidence": [ { "database": "UniProtKB", "id": "F1NTP8", "url": "https://www.uniprot.org/uniprotkb/F1NTP8" } ], "pmid": "" }, { "name": "phospholipase A1 activity", "id": "GO:0008970", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008970", "evidence": [ { "database": "UniProtKB", "id": "F1NTP8", "url": "https://www.uniprot.org/uniprotkb/F1NTP8" } ], "pmid": "" }, { "name": "monoacylglycerol lipase activity", "id": "GO:0047372", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0047372", "evidence": [ { "database": "UniProtKB", "id": "F1NTP8", "url": "https://www.uniprot.org/uniprotkb/F1NTP8" } ], "pmid": "" }, { "name": "acetylesterase activity", "id": "GO:0008126", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008126", "evidence": [ { "database": "UniProtKB", "id": "F1NTP8", "url": "https://www.uniprot.org/uniprotkb/F1NTP8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "phosphatidylcholine metabolic process", "id": "GO:0046470", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046470", "evidence": [ { "database": "UniProtKB", "id": "F1NTP8", "url": "https://www.uniprot.org/uniprotkb/F1NTP8" } ], "pmid": "" }, { "name": "medium-chain fatty acid catabolic process", "id": "GO:0051793", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051793", "evidence": [ { "database": "UniProtKB", "id": "F1NTP8", "url": "https://www.uniprot.org/uniprotkb/F1NTP8" } ], "pmid": "" }, { "name": "medium-chain fatty acid biosynthetic process", "id": "GO:0051792", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051792", "evidence": [ { "database": "UniProtKB", "id": "F1NTP8", "url": "https://www.uniprot.org/uniprotkb/F1NTP8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 123, "end_pos": 125, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "15801", "name": "", "equation": "a 1,2-diacyl-sn-glycero-3-phosphocholine + H2O = a 1-acyl-sn-glycero-3-phosphocholine + a fatty acid + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XR66-1", "A0A8V0YL25-1", "A0A8V0ZLQ3-1", "A0A8V0ZFF7-1", "A0A8V0ZFG5-1", "H8Y6B2-1", "A0A8V1A6N8-1", "P49147-1", "A0A8V0ZCG2-1", "A0A8V0ZKA3-1", "A0A8V0ZKD2-1", "A0A8V0ZKP2-1", "A0A8V0ZEJ2-1", "A0A8V0ZL36-1", "A0A8V0ZEF8-1", "A0A8V0ZEQ6-1", "A0A8V0ZD97-1", "A0A8V0Z5J2-1", "Q5ZJF4-1", "F1NTP8-1", "A0A8V0Y4T1-1" ], "evidence": [ { "id": "15801", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/15801" } ] }, { "id": "18689", "name": "", "equation": "a 1,2-diacyl-sn-glycero-3-phosphocholine + H2O = a 2-acyl-sn-glycero-3-phosphocholine + a fatty acid + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0ZYA6-1", "P11602-1", "F1NTP8-1", "A0A1D5P986-1", "A0A8V0Y4T1-1" ], "evidence": [ { "id": "18689", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/18689" } ] }, { "id": "40479", "name": "", "equation": "1-O-hexadecyl-2-acetyl-sn-glycero-3-phosphocholine + H2O = 1-O-hexadecyl-sn-glycero-3-phosphocholine + acetate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q5ZMS2-1", "A0A8V0ZR27-1", "F1NTP8-1", "A0A8V0Y4T1-1" ], "evidence": [ { "id": "40479", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/40479" } ] }, { "id": "40483", "name": "", "equation": "1-hexadecanoyl-2-(5-oxopentanoyl)-sn-glycero-3-phosphocholine + H2O = 5-oxopentanoate + 1-hexadecanoyl-sn-glycero-3-phosphocholine + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1NTP8-1", "A0A8V0Y4T1-1" ], "evidence": [ { "id": "40483", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/40483" } ] }, { "id": "41159", "name": "", "equation": "1-hexadecanoyl-2-glutaroyl-sn-glycero-3-phosphocholine + H2O = glutarate + 1-hexadecanoyl-sn-glycero-3-phosphocholine + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1NTP8-1", "A0A8V0Y4T1-1" ], "evidence": [ { "id": "41159", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/41159" } ] }, { "id": "41179", "name": "", "equation": "1-hexadecanoyl-2-(9-oxononanoyl)-sn-glycero-3-phosphocholine + H2O = 9-oxononanoate + 1-hexadecanoyl-sn-glycero-3-phosphocholine + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1NTP8-1", "A0A8V0Y4T1-1" ], "evidence": [ { "id": "41179", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/41179" } ] }, { "id": "41388", "name": "", "equation": "1-hexadecanoyl-2-nonadioyl-sn-glycero-3-phosphocholine + H2O = nonanedioate + 1-hexadecanoyl-sn-glycero-3-phosphocholine + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1NTP8-1", "A0A8V0Y4T1-1" ], "evidence": [ { "id": "41388", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/41388" } ] }, { "id": "54388", "name": "", "equation": "1-tetradecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine + H2O = 2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine + tetradecanoate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1NTP8-1", "A0A8V0Y4T1-1" ], "evidence": [ { "id": "54388", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/54388" } ] }, { "id": "54392", "name": "", "equation": "1-tetradecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine + H2O = 1-tetradecanoyl-sn-glycero-3-phosphocholine + (9Z,12Z)-octadecadienoate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1NTP8-1", "A0A8V0Y4T1-1" ], "evidence": [ { "id": "54392", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/54392" } ] }, { "id": "54396", "name": "", "equation": "1-tetradecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine + H2O = 2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphocholine + tetradecanoate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1NTP8-1", "A0A8V0Y4T1-1" ], "evidence": [ { "id": "54396", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/54396" } ] }, { "id": "54400", "name": "", "equation": "1-tetradecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine + H2O = 2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine + tetradecanoate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1NTP8-1", "A0A8V0Y4T1-1" ], "evidence": [ { "id": "54400", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/54400" } ] }, { "id": "54404", "name": "", "equation": "1,2-ditetradecanoyl-sn-glycero-3-phosphocholine + H2O = 2-tetradecanoyl-sn-glycero-3-phosphocholine + tetradecanoate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1NTP8-1", "A0A8V0Y4T1-1" ], "evidence": [ { "id": "54404", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/54404" } ] }, { "id": "54408", "name": "", "equation": "1-octadecanoyl-2-acetyl-sn-glycero-3-phosphocholine + H2O = 1-octadecanoyl-sn-glycero-3-phosphocholine + acetate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1NTP8-1", "A0A8V0Y4T1-1" ], "evidence": [ { "id": "54408", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/54408" } ] }, { "id": "54456", "name": "", "equation": "1,2-ditetradecanoyl-sn-glycero-3-phosphocholine + H2O = 1-tetradecanoyl-sn-glycero-3-phosphocholine + tetradecanoate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1NTP8-1", "A0A8V0Y4T1-1" ], "evidence": [ { "id": "54456", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/54456" } ] }, { "id": "54460", "name": "", "equation": "1-octadecanoyl-2-pentanoyl-sn-glycero-3-phosphocholine + H2O = pentanoate + 1-octadecanoyl-sn-glycero-3-phosphocholine + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1NTP8-1", "A0A8V0Y4T1-1" ], "evidence": [ { "id": "54460", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/54460" } ] }, { "id": "54464", "name": "", "equation": "1-octadecanoyl-2-hexanoyl-sn-glycero-3-phosphocholine + H2O = hexanoate + 1-octadecanoyl-sn-glycero-3-phosphocholine + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1NTP8-1", "A0A8V0Y4T1-1" ], "evidence": [ { "id": "54464", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/54464" } ] }, { "id": "54468", "name": "", "equation": "1-octadecanoyl-2-octanoyl-sn-glycero-3-phosphocholine + H2O = 1-octadecanoyl-sn-glycero-3-phosphocholine + octanoate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1NTP8-1", "A0A8V0Y4T1-1" ], "evidence": [ { "id": "54468", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/54468" } ] }, { "id": "54472", "name": "", "equation": "1-octadecanoyl-2-nonanoyl-sn-glycero-3-phosphocholine + H2O = nonanoate + 1-octadecanoyl-sn-glycero-3-phosphocholine + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1NTP8-1", "A0A8V0Y4T1-1" ], "evidence": [ { "id": "54472", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/54472" } ] }, { "id": "54552", "name": "", "equation": "1-O-hexadecyl-2-nonadioyl-sn-glycero-3-phosphocholine + H2O = nonanedioate + 1-O-hexadecyl-sn-glycero-3-phosphocholine + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1NTP8-1", "A0A8V0Y4T1-1" ], "evidence": [ { "id": "54552", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/54552" } ] }, { "id": "R-GGA-5694485", "name": "ABHD3 hydrolyses LPC(14:0) to 1AGPC", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [ "R-ALL-5694502" ], "output_participant_list": [ "R-ALL-5694457" ], "enzyme_list": [ "F1NTP8-1" ], "evidence": [ { "id": "R-GGA-5694485", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5694485" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-5694457", "participant_name": "1AGPC [plasma membrane]", "crossref": [ { "id": "11230", "database": "ChEBI", "url": "" }, { "id": "1-Acylglycero-Phosphocholines", "database": "RiceCyc", "url": "" } ] }, { "participant_id": "R-ALL-5694502", "participant_name": "LPC(14:0) [plasma membrane]", "crossref": [ { "id": "64483", "database": "ChEBI", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A0A1D5P986", "gene_name": "LIPG", "activity": [ { "ec_number": "3.1.1.32", "activity": "a 1,2-diacyl-sn-glycero-3-phosphocholine + H2O = a 2-acyl-sn-glycero-3-phosphocholine + a fatty acid + H(+).", "evidence": [ { "id": "A0A1D5P986", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P986" } ] }, { "ec_number": "3.1.1.3", "activity": "a triacylglycerol + H2O = a diacylglycerol + a fatty acid + H(+).", "evidence": [ { "id": "A0A1D5P986", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P986" } ] }, { "ec_number": "3.1.1.3", "activity": "", "evidence": [ { "id": "A0A1D5P986", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P986" } ] }, { "ec_number": "3.1.1.32", "activity": "", "evidence": [ { "id": "A0A1D5P986", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P986" } ] } ] }, { "uniprot_ac": "A0A8V0XR66", "gene_name": "PLA2G10L", "activity": [ { "ec_number": "3.1.1.4", "activity": "a 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine + H2O = a 1-O-alkyl-sn-glycero-3-phosphocholine + a fatty acid + H(+).", "evidence": [ { "id": "A0A8V0XR66", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XR66" } ] }, { "ec_number": "3.1.1.4", "activity": "", "evidence": [ { "id": "A0A8V0XR66", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XR66" } ] } ] }, { "uniprot_ac": "A0A8V0Y4T1", "gene_name": "ABHD1", "activity": [ { "ec_number": "3.1.1.32", "activity": "a 1,2-diacyl-sn-glycero-3-phosphocholine + H2O = a 2-acyl-sn-glycero-3-phosphocholine + a fatty acid + H(+).", "evidence": [ { "id": "A0A8V0Y4T1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y4T1" } ] }, { "ec_number": "3.1.1.4", "activity": "a 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine + H2O = a 1-O-alkyl-sn-glycero-3-phosphocholine + a fatty acid + H(+).", "evidence": [ { "id": "A0A8V0Y4T1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y4T1" } ] }, { "ec_number": "3.1.1.32", "activity": "", "evidence": [ { "id": "A0A8V0Y4T1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y4T1" } ] }, { "ec_number": "3.1.1.4", "activity": "", "evidence": [ { "id": "A0A8V0Y4T1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y4T1" } ] } ] }, { "uniprot_ac": "A0A8V0YL25", "gene_name": "PRDX6", "activity": [ { "ec_number": "1.11.1.27", "activity": "a hydroperoxide + 2 glutathione = an alcohol + glutathione disulfide + H2O.", "evidence": [ { "id": "A0A8V0YL25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL25" } ] }, { "ec_number": "1.11.1.27", "activity": "", "evidence": [ { "id": "A0A8V0YL25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL25" } ] } ] }, { "uniprot_ac": "A0A8V0Z5J2", "gene_name": "PLB1", "activity": [ { "ec_number": "3.1.1.4", "activity": "a 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine + H2O = a 1-O-alkyl-sn-glycero-3-phosphocholine + a fatty acid + H(+).", "evidence": [ { "id": "A0A8V0Z5J2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5J2" } ] }, { "ec_number": "3.1.1.3", "activity": "a triacylglycerol + H2O = a diacylglycerol + a fatty acid + H(+).", "evidence": [ { "id": "A0A8V0Z5J2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5J2" } ] }, { "ec_number": "3.1.1.5", "activity": "a 1-acyl-sn-glycero-3-phosphocholine + H2O = sn-glycerol 3-phosphocholine + a fatty acid + H(+).", "evidence": [ { "id": "A0A8V0Z5J2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5J2" } ] }, { "ec_number": "3.1.1.4", "activity": "", "evidence": [ { "id": "A0A8V0Z5J2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5J2" } ] }, { "ec_number": "3.1.1.5", "activity": "", "evidence": [ { "id": "A0A8V0Z5J2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5J2" } ] }, { "ec_number": "3.1.1.3", "activity": "", "evidence": [ { "id": "A0A8V0Z5J2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5J2" } ] } ] }, { "uniprot_ac": "A0A8V0ZCG2", "gene_name": "PLA2G4B", "activity": [ { "ec_number": "3.1.1.4", "activity": "a 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine + H2O = a 1-O-alkyl-sn-glycero-3-phosphocholine + a fatty acid + H(+).", "evidence": [ { "id": "A0A8V0ZCG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCG2" } ] }, { "ec_number": "3.1.1.4", "activity": "", "evidence": [ { "id": "A0A8V0ZCG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCG2" } ] } ] }, { "uniprot_ac": "A0A8V0ZD97", "gene_name": "LOC771560", "activity": [ { "ec_number": "3.1.1.4", "activity": "a 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine + H2O = a 1-O-alkyl-sn-glycero-3-phosphocholine + a fatty acid + H(+).", "evidence": [ { "id": "A0A8V0ZD97", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD97" } ] }, { "ec_number": "3.1.1.4", "activity": "", "evidence": [ { "id": 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This record is derived from a genomic sequence (NC_052572.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003643114", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003643114" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NJL8", "url": "https://www.uniprot.org/uniprotkb/F1NJL8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "NR2F1", "url": "https://www.uniprot.org/uniprotkb/F1NJL8", "locus": { "chromosome": "Z", "start_pos": 59190896, "end_pos": 59200384, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013574", "url": "https://www.ensembl.org/id/ENSGALG00010013574" } ] } } ], "crossref": [ { "id": "F1NJL8", "url": "https://alphafold.ebi.ac.uk/entry/F1NJL8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000027907", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000027907", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd06948", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06948", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd06958", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06958", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100859519", "url": "https://www.ncbi.nlm.nih.gov/gene/100859519", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000536", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000536", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001628", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001628", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001723", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001723", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013088", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013088", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035500", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035500", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050274", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050274", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:100859519", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100859519", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A1D5PFG4", "url": "https://www.orthodb.org/?gene=A0A1D5PFG4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YKJ8", "url": "https://www.orthodb.org/?gene=A0A8V0YKJ8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NJL8", "url": "https://www.orthodb.org/?gene=F1NJL8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24083", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24083", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00104", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00104", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00105", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00105", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-383280", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-383280", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_003643114", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003643114", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5PFG4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PFG4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PFG4-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PFG4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YKJ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKJ8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YKJ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKJ8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NJL8", "url": "https://www.uniprot.org/uniprotkb/F1NJL8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NJL8-1", "url": "https://www.uniprot.org/uniprotkb/F1NJL8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAMVVSSWRDPQEDVAGGTPSGPNPAAQPAREQPPQQQGGSAAPHTPQTPSQPGPPSTPGTAGDKGPGQQGSGQSQQHIECVVCGDKSSGKHYGQFTCEGCKSFFKRSVRRNLTYTCRANRNCPIDQHHRNQCQYCRLKKCLKVGMRREAVQRGRMPPTQPNPGQYALTNGDPLNGHCYLSGYISLLLRAEPYPTSRYGSQCMQPNNIMGIENICELAARLLFSAVEWARNIPFFPDLQITDQVALLRLTWSELFVLNAAQCSMPLHVAPLLAAAGLHASPMSADRVVAFMDHIRIFQEQVEKLKALHVDSAEYSCLKAIVLFTSDACGLSDAAHIESLQEKSQCALEEYVRSQYPNQPSRFGKLLLRLPSLRTVSSSVIEQLFFVRLVGKTPIETLIRDMLLSGSSFNWPYMSIQCS", "length": 418, "header": "tr|F1NJL8-1|F1NJL8_CHICK Isoform 1 of Nuclear receptor subfamily 2 group F member 1 OS=Gallus gallus OX=9031 GN=NR2F1 PE=3 SV=2 CANONICAL=F1NJL8-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PFG4-1", "url": "https://www.uniprot.org/uniprotkb/F1NJL8/entry#A0A1D5PFG4-1", "sequence": { "sequence": "MPPTQPNPGQYALTNGDPLNGHCYLSGYISLLLRAEPYPTSRYGSQCMQPNNIMGIENICELAARLLFSAVEWARNIPFFPDLQITDQVALLRLTWSELFVLNAAQCSMPLHVAPLLAAAGLHASPMSADRVVAFMDHIRIFQEQVEKLKALHVDSAEYSCLKAIVLFTSDACGLSDAAHIESLQEKSQCALEEYVRSQYPNQPSRFGKLLLRLPSLRTVSSSVIEQLFFVRLVGKTPIETLIRDMLLSGSSFNWPYMSIQCS", "length": 263, "header": "tr|A0A1D5PFG4-1|A0A1D5PFG4_CHICK Computationally mapped isoform of Nuclear receptor subfamily 2 group F member 1 OS=Gallus gallus OX=9031 GN=NR2F1 PE=4 SV=2 CANONICAL=F1NJL8-1" }, "locus": { "chromosome": "Z", "start_pos": 59196929, "end_pos": 59191900, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032630.1", "url": "https://www.ensembl.org/id/ENSGALT00010032630.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019337.1", "url": "https://www.ensembl.org/id/ENSGALP00010019337.1" } ] } }, { "isoform_ac": "A0A8V0YKJ8-1", "url": "https://www.uniprot.org/uniprotkb/F1NJL8/entry#A0A8V0YKJ8-1", "sequence": { "sequence": "MAMVVSSWRDPQEDVAGGTPSGPNPAAQPAREQPPQQQGGSAAPHTPQTPSQPGPPSTPGTAGDKGPGQQGSGQSQQHIECVVCGDKSSGKHYGQFTCEGCKSFFKRSVRRNLTYTCRANRNCPIDQHHRNQCQYCRLKKCLKVGMRREAVQRGRMPPTQPNPGQYALTNGDPLNGHCYLSGYISLLLRAEPYPTSRYGSQCMQPNNIMGIENICELAARLLFSAVEWARNIPFFPDLQITDQVALLRLTWSELFVLNAAQCSMPLHVAPLLAAAGLHASPMSADRVVAFMDHIRIFQEQVEKLKALHVDSAEYSCLKAIVLFTSDACGLSDAAHIESLQEKSQCALEEYVRSQYPNQPSRFGKLLLRLPSLRTVSSSVIEQLFFVRLEEKKKIIIIKDKKAKKKIKKNTKK", "length": 412, "header": "tr|A0A8V0YKJ8-1|A0A8V0YKJ8_CHICK Computationally mapped isoform of Nuclear receptor subfamily 2 group F member 1 OS=Gallus gallus OX=9031 GN=NR2F1 PE=3 SV=1 CANONICAL=F1NJL8-1" }, "locus": { "chromosome": "Z", "start_pos": 59200185, "end_pos": 59191542, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032631.1", "url": "https://www.ensembl.org/id/ENSGALT00010032631.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019338.1", "url": "https://www.ensembl.org/id/ENSGALP00010019338.1" } ] } }, { "isoform_ac": "F1NJL8-1", "url": "https://www.uniprot.org/uniprotkb/F1NJL8/entry#F1NJL8-1", "sequence": { "sequence": "MAMVVSSWRDPQEDVAGGTPSGPNPAAQPAREQPPQQQGGSAAPHTPQTPSQPGPPSTPGTAGDKGPGQQGSGQSQQHIECVVCGDKSSGKHYGQFTCEGCKSFFKRSVRRNLTYTCRANRNCPIDQHHRNQCQYCRLKKCLKVGMRREAVQRGRMPPTQPNPGQYALTNGDPLNGHCYLSGYISLLLRAEPYPTSRYGSQCMQPNNIMGIENICELAARLLFSAVEWARNIPFFPDLQITDQVALLRLTWSELFVLNAAQCSMPLHVAPLLAAAGLHASPMSADRVVAFMDHIRIFQEQVEKLKALHVDSAEYSCLKAIVLFTSDACGLSDAAHIESLQEKSQCALEEYVRSQYPNQPSRFGKLLLRLPSLRTVSSSVIEQLFFVRLVGKTPIETLIRDMLLSGSSFNWPYMSIQCS", "length": 418, "header": "tr|F1NJL8-1|F1NJL8_CHICK Isoform 1 of Nuclear receptor subfamily 2 group F member 1 OS=Gallus gallus OX=9031 GN=NR2F1 PE=3 SV=2 CANONICAL=F1NJL8-1" }, "locus": { "chromosome": "Z", "start_pos": 59200185, "end_pos": 59191900, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032633.1", "url": "https://www.ensembl.org/id/ENSGALT00010032633.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019339.1", "url": "https://www.ensembl.org/id/ENSGALP00010019339.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 19, "start_aa": "Thr", "end_pos": 19, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr19", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 58, "start_aa": "Thr", "end_pos": 58, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr58", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:100859519", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100859519", "resource": "KEGG Pathway" }, { "id": "R-GGA-383280", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-383280", "resource": "Reactome", "description": "Nuclear Receptor transcription pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "F1NJL8", "url": "https://www.uniprot.org/uniprotkb/F1NJL8" } ], "pmid": "" }, { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "F1NJL8", "url": "https://www.uniprot.org/uniprotkb/F1NJL8" } ], "pmid": "" }, { "name": "nervous system development", "id": "GO:0007399", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007399", "evidence": [ { "database": "UniProtKB", "id": "F1NJL8", "url": "https://www.uniprot.org/uniprotkb/F1NJL8" } ], "pmid": "" }, { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "F1NJL8", "url": "https://www.uniprot.org/uniprotkb/F1NJL8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1NJL8", "url": "https://www.uniprot.org/uniprotkb/F1NJL8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 6, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "F1NJL8", "url": "https://www.uniprot.org/uniprotkb/F1NJL8" } ], "pmid": "" }, { "name": "DNA-binding transcription repressor activity, RNA polymerase II-specific", "id": "GO:0001227", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001227", "evidence": [ { "database": "UniProtKB", "id": "F1NJL8", "url": "https://www.uniprot.org/uniprotkb/F1NJL8" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "F1NJL8", "url": "https://www.uniprot.org/uniprotkb/F1NJL8" } ], "pmid": "" }, { "name": "nuclear receptor activity", "id": "GO:0004879", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004879", "evidence": [ { "database": "UniProtKB", "id": "F1NJL8", "url": "https://www.uniprot.org/uniprotkb/F1NJL8" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "F1NJL8", "url": "https://www.uniprot.org/uniprotkb/F1NJL8" } ], "pmid": "" }, { "name": "sequence-specific DNA binding", "id": "GO:0043565", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043565", "evidence": [ { "database": "UniProtKB", "id": "F1NJL8", "url": "https://www.uniprot.org/uniprotkb/F1NJL8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 112, "end_pos": 114, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1NJL8-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 418, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1NJL8-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1NJL8" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 19, 58 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 112, "end_pos": 114 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1NQ29-1", "uniprot_ac": "F1NQ29", "uniprot_id": "F1NQ29_CHICK", "mass": { "chemical_mass": 65059.0, "monoisotopic_mass": 65059.0 }, "refseq": { "ac": "XP_424818", "name": "protein AF-9 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_424818" }, "gene_names": [ { "name": "MLLT3", "type": "recommended", "evidence": [ { "id": "F1NQ29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NQ29" } ] }, { "name": "MLLT3", "type": "synonym", "evidence": [ { "id": "XP_424818", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_424818" } ] } ], "protein_names": [ { "name": "MLLT3 super elongation complex subunit", "type": "synonym", "evidence": [ { "id": "F1NQ29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NQ29/entry#names_and_taxonomy" } ] }, { "name": "protein AF-9 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_424818", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_424818" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052572.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 19, 2013 this sequence version replaced XP_424818.3. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_424818", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_424818" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NQ29", "url": "https://www.uniprot.org/uniprotkb/F1NQ29" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MLLT3", "url": "https://www.uniprot.org/uniprotkb/F1NQ29", "locus": { "chromosome": "Z", "start_pos": 34482901, "end_pos": 34595619, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013967", "url": "https://www.ensembl.org/id/ENSGALG00010013967" } ] } } ], "crossref": [ { "id": "F1NQ29", "url": "https://alphafold.ebi.ac.uk/entry/F1NQ29", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000015078", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000015078", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd16906", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16906", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "427234", "url": "https://www.ncbi.nlm.nih.gov/gene/427234", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR038704", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038704", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040930", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040930", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052790", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052790", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055129", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055129", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:427234", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427234", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MASSXCK", "url": "https://omabrowser.org/oma/group/MASSXCK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PVW7", "url": "https://www.orthodb.org/?gene=A0A1D5PVW7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YMC4", "url": "https://www.orthodb.org/?gene=A0A8V0YMC4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NQ29", "url": "https://www.orthodb.org/?gene=F1NQ29", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47827", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47827", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47827:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47827:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03366", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03366", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17793", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17793", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-112382", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-112382", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-674695", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-674695", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-75955", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-75955", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_424818", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_424818", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5PVW7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PVW7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PVW7-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PVW7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YMC4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMC4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YMC4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMC4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NQ29", "url": "https://www.uniprot.org/uniprotkb/F1NQ29", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NQ29-1", "url": "https://www.uniprot.org/uniprotkb/F1NQ29-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAGACAVQVKLELGHRAQVRKKPTVEGFTHDWMVFVRGPEHSNIQHFVEKVVFHLHESFPRPKRVCKDPPYKVEESGYAGFILPIEVYFKNKEEPKKVRFDYDLFLHLEGHPPVNHLRCEKLTFNNPTEEFRRKLLKAGGIMVMTDGTSFSSGQSLHLPNLPSNSLSFSEVKKKSSHGPKDPTKILNINSSSGSTNSFSKPHKLTKEHKEKTSKDSKEQKSAFKEPSREHNKSSKESSKKPKENKPLKDEKLVPKMAFKEPKSMSKEPKSENTPILTITGGQQQEKKTPIKRPSVLDSDEPSAKKRKKNVSESLFKSFPNAPSLVLTCSADKKQTKDRSQLKMGRVKIESDTLEKKTSTLPPFDDIIDPNDSDVEENMSSKSESDQPSPASSSSSSSSSFTPSQNSRQQGPLRSIMKDLHSDDNEDESEEPDDNDNDSELERPVNTRGGSRSRRVSLSDGSDSDSNSASSPPRHEPAPPLLKTNSNQILEVKSPIKQNKSDKQIKNGDCDKAYLDELVELHRRLMTLRERHVLQQIVNLIEETGHFHITNTTFDFDLCSLDKTTVRKLQSYLETSGTS", "length": 578, "header": "tr|F1NQ29-1|F1NQ29_CHICK Isoform 1 of MLLT3 super elongation complex subunit OS=Gallus gallus OX=9031 GN=MLLT3 PE=4 SV=2 CANONICAL=F1NQ29-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PVW7-1", "url": "https://www.uniprot.org/uniprotkb/F1NQ29/entry#A0A1D5PVW7-1", "sequence": { "sequence": "MAGACAVQVKLELGHRAQVRKKPTVEGFTHDWMVFVRGPEHSNIQHFVEKVVFHLHESFPRPKRVCKDPPYKVEESGYAGFILPIEVYFKNKIMVMTDGTSFSSGQSLHLPNLPSNSLSFSEVKKKSSHGPKDPTKILNINSSSGSTNSFSKPHKLTKEHKEKTSKDSKEQKSAFKEPSREHNKSSKESSKKPKENKPLKDEKLVPKMAFKEPKSMSKEPKSENTPILTITGGQQQEKKTPIKRPSVLDSDEPSAKKRKKNVSESLFKSFPNAPSLVLTCSADKKQTKDRSQLKMGRVKIESDTLEKKTSTLPPFDDIIDPNDSDVEENMSSKSESDQPSPASSSSSSSSSFTPSQNSRQQGPLRSIMKDLHSDDNEDESEEPDDNDNDSELERPVNTRGGSRSRRVSLSDGSDSDSNSASSPPRHEPAPPLLKTNSNQILEVKSPIKQNKSDKQIKNGDCDKAYLDELVELHRRLMTLRERHVLQQIVNLIEETGHFHITNTTFDFDLCSLDKTTVRKLQSYLETSGTS", "length": 530, "header": "tr|A0A1D5PVW7-1|A0A1D5PVW7_CHICK Computationally mapped isoform of MLLT3 super elongation complex subunit OS=Gallus gallus OX=9031 GN=MLLT3 PE=4 SV=1 CANONICAL=F1NQ29-1" }, "locus": { "chromosome": "Z", "start_pos": 34595320, "end_pos": 34484383, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033497.1", "url": "https://www.ensembl.org/id/ENSGALT00010033497.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019755.1", "url": "https://www.ensembl.org/id/ENSGALP00010019755.1" } ] } }, { "isoform_ac": "A0A8V0YMC4-1", "url": "https://www.uniprot.org/uniprotkb/F1NQ29/entry#A0A8V0YMC4-1", "sequence": { "sequence": "MVFVRGPEHSNIQHFVEKVVFHLHESFPRPKRVCKDPPYKVEESGYAGFILPIEVYFKNKEEPKKVRFDYDLFLHLEGHPPVNHLRCEKLTFNNPTEEFRRKLLKAGGIMVMTDGTSFSSGQSLHLPNLPSNSLSFSEVKKKSSHGPKDPTKILNINSSSGSTNSFSKPHKLTKEHKEKTSKDSKEQKSAFKEPSREHNKSSKESSKKPKENKPLKDEKLVPKMAFKEPKSMSKEPKSENTPILTITGGQQQEKKTPIKRPSVLDSDEPSAKKRKKNVSESLFKSFPNAPSLVLTCSADKKQTKDRSQLKMGRVKIESDTLEKKTSTLPPFDDIIDPNDSDVEENMSSKSESDQPSPASSSSSSSSSFTPSQNSRQQGPLRSIMKDLHSDDNEDESEEPDDNDNDSELERPVNTRGGSRSRRVSLSDGSDSDSNSASSPPRHEPAPPLLKTNSNQILEVKSPIKQNKSDKQIKNGDCDKAYLDELVELHRRLMTLRERHVLQQIVNLIEETGHFHITNTTFDFDLCSLDKTTVRKLQSYLETSGTS", "length": 546, "header": "tr|A0A8V0YMC4-1|A0A8V0YMC4_CHICK Computationally mapped isoform of MLLT3 super elongation complex subunit OS=Gallus gallus OX=9031 GN=MLLT3 PE=4 SV=1 CANONICAL=F1NQ29-1" }, "locus": { "chromosome": "Z", "start_pos": 34594986, "end_pos": 34484383, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033502.1", "url": "https://www.ensembl.org/id/ENSGALT00010033502.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019758.1", "url": "https://www.ensembl.org/id/ENSGALP00010019758.1" } ] } }, { "isoform_ac": "F1NQ29-1", "url": "https://www.uniprot.org/uniprotkb/F1NQ29/entry#F1NQ29-1", "sequence": { "sequence": "MAGACAVQVKLELGHRAQVRKKPTVEGFTHDWMVFVRGPEHSNIQHFVEKVVFHLHESFPRPKRVCKDPPYKVEESGYAGFILPIEVYFKNKEEPKKVRFDYDLFLHLEGHPPVNHLRCEKLTFNNPTEEFRRKLLKAGGIMVMTDGTSFSSGQSLHLPNLPSNSLSFSEVKKKSSHGPKDPTKILNINSSSGSTNSFSKPHKLTKEHKEKTSKDSKEQKSAFKEPSREHNKSSKESSKKPKENKPLKDEKLVPKMAFKEPKSMSKEPKSENTPILTITGGQQQEKKTPIKRPSVLDSDEPSAKKRKKNVSESLFKSFPNAPSLVLTCSADKKQTKDRSQLKMGRVKIESDTLEKKTSTLPPFDDIIDPNDSDVEENMSSKSESDQPSPASSSSSSSSSFTPSQNSRQQGPLRSIMKDLHSDDNEDESEEPDDNDNDSELERPVNTRGGSRSRRVSLSDGSDSDSNSASSPPRHEPAPPLLKTNSNQILEVKSPIKQNKSDKQIKNGDCDKAYLDELVELHRRLMTLRERHVLQQIVNLIEETGHFHITNTTFDFDLCSLDKTTVRKLQSYLETSGTS", "length": 578, "header": "tr|F1NQ29-1|F1NQ29_CHICK Isoform 1 of MLLT3 super elongation complex subunit OS=Gallus gallus OX=9031 GN=MLLT3 PE=4 SV=2 CANONICAL=F1NQ29-1" }, "locus": { "chromosome": "Z", "start_pos": 34595320, "end_pos": 34484383, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033493.1", "url": "https://www.ensembl.org/id/ENSGALT00010033493.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019753.1", "url": "https://www.ensembl.org/id/ENSGALP00010019753.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:427234", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427234", "resource": "KEGG Pathway" }, { "id": "R-GGA-112382", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-112382", "resource": "Reactome", "description": "Formation of RNA Pol II elongation complex" }, { "id": "R-GGA-674695", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-674695", "resource": "Reactome", "description": "RNA Polymerase II Pre-transcription Events" }, { "id": "R-GGA-75955", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-75955", "resource": "Reactome", "description": "RNA Polymerase II Transcription Elongation" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287A4E4-1", "protein_name": "MLLT3 super elongation complex subunit", "gene_name": "MLLT3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MASSCAVQVKLELGHRAQVRKKPTVEGFTHDWMVFVRGPEHSNIQHFVEKVVFHLHESFPRPKRVCKDPPYKVEESGYAGFILPIEVYFKNKEEPKKVRFDYDLFLHLEGHPPVNHLRCEKLTFNNPTEEFRRKLLKAGGDPNRSIHTSSSSSSSSCSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTSFSKPHKLMKEHKEKPSKDSREHKSAFKEPSRDHNKSSKESSKKPKENKPLKEEKIVPKMAFKEPKPMSKEPKPDSNLLTITSGQQDKKAPSKRPPISDSEELSAKKRKKSSSEALFKSFSSAPPLILTCSADKKQIKDKSHVKMGKVKVESETSEKKKSALPPFDDIVDPNDSDVEENMSSKSDSEQPSPASSSSSSSSSFTPSQTRQQGPLRSIMKDLHSDDNEEESDEAEDNDNDSEMERPVNRGGSRSRRVSLSDGSDSESSSASSPLHHEPPPPLLKTNNNQILEVKSPIKQSKSDKQIKNGECDKAYLDELVELHRRLMTLRERHILQQIVNLIEETGHFHITNTTFDFDLCSLDKTTVRKLQSYLETSGTS", "length": 567 }, "evidence": [ { "id": "F1NQ29", "url": "https://omabrowser.org/oma/group/F1NQ29/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8I5ZRB6-1", "protein_name": "MLLT3, super elongation complex subunit", "gene_name": "Mllt3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASSCAVQVKLELGHRAQVRKKPTVEGFTHDWMVFVRGPEHSNIQHFVEKVVFHLHESFPRPKRVCKDPPYKVEESGYAGFILPIEVYFKNKEEPKKVRFDYDLFLHLEGHPPVNHLRCEKLTFNNPTEDFRRKLLKAGGDPNRSIHTSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTSFSKPHKLMKEHKEKPSKDSREHKSAFKEPSRDHNKSSKDSSKKPKENKPLKEEKIVPKMAFKEPKPMSKEPKADSNLLTVTSAQQDKKAPSKRPPVSDSEELSAKKRKKSSSEALFKSFSSAPPLILTCSADKKQIKDKSHVKMGKVKIESETSEKKKSTLPPFDDIVDPNDSDVEENMSSKSDSEQPSPASSSSSSSSSFTPSQTRQQGPLRSIMKDLHSDDNEEESDEAEDNDNDSEMERPVNRGGSRSRRVSLSDGSDSESSSASSPLHHEPPPPLLKTNNNQILEVKSPIKQSKSDKQIKNGECDKAYLDELVELHRRLMTLRERHILQQIVNLIEETGHFHITNTTFDFDLCSLDKTTVRKLQSYLETSGTS", "length": 569 }, "evidence": [ { "id": "F1NQ29", "url": "https://omabrowser.org/oma/group/F1NQ29/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A2AM29-1", "protein_name": "Protein AF-9", "gene_name": "Mllt3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASSCAVQVKLELGHRAQVRKKPTVEGFTHDWMVFVRGPEHSNIQHFVEKVVFHLHESFPRPKRVCKDPPYKVEESGYAGFILPIEVYFKNKEEPKKVRFDYDLFLHLEGHPPVNHLRCEKLTFNNPTEDFRRKLLKAGGDPNRSIHTSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTSFSKPHKLMKEHKEKPSKDSREHKSAFKEPSRDHNKSSKDSSKKPKENKPLKEEKIVPKMAFKEPKPMSKEPKADSNLLTVTSGQQDKKAPSKRPPASDSEELSAKKRKKSSSEALFKSFSSAPPLILTCSADKKQIKDKSHVKMGKVKIESETSEKKKSMLPPFDDIVDPNDSDVEENMSSKSDSEQPSPASSSSSSSSSFTPSQTRQQGPLRSIMKDLHSDDNEEESDEAEDNDNDSEMERPVNRGGSRSRRVSLSDGSDSESSSASSPLHHEPPPPLLKTNNNQILEVKSPIKQSKSDKQIKNGECDKAYLDELVELHRRLMTLRERHILQQIVNLIEETGHFHITNTTFDFDLCSLDKTTVRKLQSYLETSGTS", "length": 569 }, "evidence": [ { "id": "F1NQ29", "url": "https://omabrowser.org/oma/group/F1NQ29/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F1MNI7-1", "protein_name": "MLLT3 super elongation complex subunit", "gene_name": "MLLT3", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MASSCAVQVKLELGHRAQVRKKPTVEGFTHDWMVFVRGPEHSNIQHFVEKVVFHLHESFPRPKRVCKDPPYKVEESGYAGFILPIEVYFKNKEEPKKVRFDYDLFLHLEGHPPVNHLRCEKLTFNNPTEEFRRKLLKAGGDPNRSIHTSSSSSSSSCSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTSFSKPHKLMKEHKEKPSKDSREHKSAFKEPSRDHNKSSKESSKKPKENKPLKEEKIVPKMAFKEPKPMSKEPKPDSNLLTITSGQQDKKAPSKRPPISDSEELSAKKRKKSSSEALFKSFSSAPPLILTCSADKKQIKDKSHVKMGKVKIESETSEKKKSTLPPFDDIVDPNDSDVEENMSSKSDSEQPSPASSSSSSSFTPSQTRQQGPLRSIMKDLHSDDNEEESDEAEDNDNDSEMERPVNRGGSRSRRVSLSDGSDSESSSASSPLHHEPPPPLLKTNNNQILEVKSPIKQSKSDKQIKNGECDKAYLDELVELHRRLMTLRERHILQQIVNLIEETGHFHITNTTFDFDLCSLDKTTVRKLQSYLETSGTS", "length": 567 }, "evidence": [ { "id": "F1NQ29", "url": "https://omabrowser.org/oma/group/F1NQ29/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P42568-1", "protein_name": "Protein AF-9", "gene_name": "MLLT3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MASSCAVQVKLELGHRAQVRKKPTVEGFTHDWMVFVRGPEHSNIQHFVEKVVFHLHESFPRPKRVCKDPPYKVEESGYAGFILPIEVYFKNKEEPRKVRFDYDLFLHLEGHPPVNHLRCEKLTFNNPTEDFRRKLLKAGGDPNRSIHTSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTSFSKPHKLMKEHKEKPSKDSREHKSAFKEPSRDHNKSSKESSKKPKENKPLKEEKIVPKMAFKEPKPMSKEPKPDSNLLTITSGQDKKAPSKRPPISDSEELSAKKRKKSSSEALFKSFSSAPPLILTCSADKKQIKDKSHVKMGKVKIESETSEKKKSTLPPFDDIVDPNDSDVEENISSKSDSEQPSPASSSSSSSSSFTPSQTRQQGPLRSIMKDLHSDDNEEESDEVEDNDNDSEMERPVNRGGSRSRRVSLSDGSDSESSSASSPLHHEPPPPLLKTNNNQILEVKSPIKQSKSDKQIKNGECDKAYLDELVELHRRLMTLRERHILQQIVNLIEETGHFHITNTTFDFDLCSLDKTTVRKLQSYLETSGTS", "length": 568 }, "evidence": [ { "id": "F1NQ29", "url": "https://omabrowser.org/oma/group/F1NQ29/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1NQ29", "url": "https://www.uniprot.org/uniprotkb/F1NQ29" } ], "pmid": "" }, { "name": "transcription elongation factor complex", "id": "GO:0008023", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008023", "evidence": [ { "database": "UniProtKB", "id": "F1NQ29", "url": "https://www.uniprot.org/uniprotkb/F1NQ29" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 6, "go_terms": [ { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "F1NQ29", "url": "https://www.uniprot.org/uniprotkb/F1NQ29" } ], "pmid": "" }, { "name": "histone binding", "id": "GO:0042393", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042393", "evidence": [ { "database": "UniProtKB", "id": "F1NQ29", "url": "https://www.uniprot.org/uniprotkb/F1NQ29" } ], "pmid": "" }, { "name": "modification-dependent protein binding", "id": "GO:0140030", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140030", "evidence": [ { "database": "UniProtKB", "id": "F1NQ29", "url": "https://www.uniprot.org/uniprotkb/F1NQ29" } ], "pmid": "" }, { "name": "histone H3K18ac reader activity", "id": "GO:0140044", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140044", "evidence": [ { "database": "UniProtKB", "id": "F1NQ29", "url": "https://www.uniprot.org/uniprotkb/F1NQ29" } ], "pmid": "" }, { "name": "histone H3K9ac reader activity", "id": "GO:0140072", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140072", "evidence": [ { "database": "UniProtKB", "id": "F1NQ29", "url": "https://www.uniprot.org/uniprotkb/F1NQ29" } ], "pmid": "" }, { "name": "histone H3K27ac reader activity", "id": "GO:0140119", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140119", "evidence": [ { "database": "UniProtKB", "id": "F1NQ29", "url": "https://www.uniprot.org/uniprotkb/F1NQ29" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "F1NQ29", "url": "https://www.uniprot.org/uniprotkb/F1NQ29" } ], "pmid": "" }, { "name": "hematopoietic stem cell differentiation", "id": "GO:0060218", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060218", "evidence": [ { "database": "UniProtKB", "id": "F1NQ29", "url": "https://www.uniprot.org/uniprotkb/F1NQ29" } ], "pmid": "" }, { "name": "positive regulation of DNA-templated transcription", "id": "GO:0045893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045893", "evidence": [ { "database": "UniProtKB", "id": "F1NQ29", "url": "https://www.uniprot.org/uniprotkb/F1NQ29" } ], "pmid": "" }, { "name": "regulation of stem cell division", "id": "GO:2000035", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000035", "evidence": [ { "database": "UniProtKB", "id": "F1NQ29", "url": "https://www.uniprot.org/uniprotkb/F1NQ29" } ], "pmid": "" }, { "name": "regulation of chromatin organization", "id": 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Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052541.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015134474", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015134474" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NYK4", "url": "https://www.uniprot.org/uniprotkb/F1NYK4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "APBA2", "url": "https://www.uniprot.org/uniprotkb/F1NYK4", "locus": { "chromosome": "10", "start_pos": 5915874, "end_pos": 5827161, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010024814", "url": "https://www.ensembl.org/id/ENSGALG00010024814" } ] } } ], "crossref": [ { "id": "F1NYK4", "url": "https://alphafold.ebi.ac.uk/entry/F1NYK4", "database": "AlphaFoldDB", 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OS=Gallus gallus OX=9031 GN=APBA2 PE=4 SV=2 CANONICAL=F1NYK4-1" }, "isoforms": [ { "isoform_ac": "A0A3Q2UF05-1", "url": "https://www.uniprot.org/uniprotkb/F1NYK4/entry#A0A3Q2UF05-1", "sequence": { "sequence": "MANRKRQSTTASMLDHRARACPTSSHNREPENEESDLPVEDYPAKEAELATIRQGSPTPLEHECNDHSGDGDSSSDYVNNTSEEEDYDEGLPEEEEGITYYIRYCPEDDSYLEGMDCNGEEYAANEEHHIETDECQEAVEEWSEGKIQHQDENEVTDRQEWQEGQDNGIQVLEDEASSLEIQDQDENIQYCQSEGGYPDYYPAEANGNSQGISPYHSRKEDAELEEQEEDIDQIVAEIKMSMSMSSINSTTEMSPEHTGTENMAHDYKETCSKGEAVHSANRHEGRPKSLNIPSASKHGGDVPRGFKAKSRTPEDRQKWPQEQMCNGLEQPRKQQRSDLNGPVDNNNTPESKKVSSFPSFVDVPGPCEPEDLIDGIIFAANYLGSTQLLSERNPSKNIRMMQAQEAVSRVKTSEGDSQALTEVDLFISTQRIKVLNADTQETMMDHALRTISYIADIGNIVVLMARRRMPRSASQDCIETTPGAQEGKKQYKMICHVFESEDAQLIAQSIGQAFSVAYQEFLRANGINPEDLSQKEYSDIINTQEMYNDDLIHFSNSENCKELQLEKQKGEILGVVIVESGWGSILPTVILANMMNGGPAARSGKLSIGDQIMSINGTSLVGLPLATCQGIIKGLKNQTQVKLNIVSCPPVTTVLIKRPDLKYQLGFSVQNGIICSLMRGGIAERGGVRVGHRIIEINGQSVVATAHEKIVQALSNSVGEIHMKTMPAAMFRLLTGQETPLYI", "length": 743, "header": "tr|A0A3Q2UF05-1|A0A3Q2UF05_CHICK Computationally mapped isoform of Amyloid beta protein binding family A member 2 OS=Gallus gallus OX=9031 GN=APBA2 PE=4 SV=1 CANONICAL=F1NYK4-1" }, "locus": { "chromosome": "10", "start_pos": 5914614, "end_pos": 5876157, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010060581.1", "url": "https://www.ensembl.org/id/ENSGALT00010060581.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010037340.1", "url": "https://www.ensembl.org/id/ENSGALP00010037340.1" } ] } }, { "isoform_ac": "A0A8V1A2A6-1", "url": "https://www.uniprot.org/uniprotkb/F1NYK4/entry#A0A8V1A2A6-1", "sequence": { "sequence": "MANRKRQSTTASMLDHRARACPTSSHNREPENEESDLPVEDYPAKEAELATIRQGSPTPLEHECNDHSGDGDSSSDYVNNTSEEEDYDEGLPEEEEGITYYIRYCPEDDSYLEGMDCNGEEYAANEEHHIETDECQEAVEEWSEGKIQHQDENEVTDRQEWQEGQDNGIQVLEDEASSLEIQDQDENIQYCQSEGGYPDYYPAEANGNSQGISPYHSRKEDAELEEQEEDIDQIVAEIKMSMSMSSINSTTEMSPEHTGTENMAHDYKETCSKGEAVHSANRHEGRPKSLNIPSASKHGGDVPRGFKAKSRTPEDRQKWPQEQMCNGLEQPRKQQRSDLNGPVDNNNTPESKKVSSFPSFVDVPGPCEPEDLIDGIIFAANYLGSTQLLSERNPSKNIRMMQAQEAVSRVKTSEGDSQALTEVDLFISTQRIKVLNADTQETMMDHALRTISYIADIGNIVVLMARRRMPRSASQDCIETTPGAQEGKKQYKMICHVFESEDAQLIAQSIGQAFSVAYQEFLRANGINPEDLSQKEYSDIINTQEMYNDDLIHFSNSENCKELQLEKQKGEILGVVIVESGWGSILPTVILANMMNGGPAARSGKLSIGDQIMSINGTSLVGLPLATCQGIIKICSLMRGGIAERGGVRVGHRIIEINGQSVVATAHEKIVQALSNSVGEIHMKTMPAAMFRLLTGQETPLYI", "length": 703, "header": "tr|A0A8V1A2A6-1|A0A8V1A2A6_CHICK Computationally mapped isoform of Amyloid beta protein binding family A member 2 OS=Gallus gallus OX=9031 GN=APBA2 PE=4 SV=1 CANONICAL=F1NYK4-1" }, "locus": { "chromosome": "10", "start_pos": 5914614, "end_pos": 5876157, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010060570.1", "url": "https://www.ensembl.org/id/ENSGALT00010060570.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010037329.1", "url": "https://www.ensembl.org/id/ENSGALP00010037329.1" } ] } }, { "isoform_ac": "A0A8V1A4E8-1", "url": "https://www.uniprot.org/uniprotkb/F1NYK4/entry#A0A8V1A4E8-1", "sequence": { "sequence": "MANRKRQSTTASMLDHRARACPTSSHNREPENEESDLPVEDYPAKEAELATIRQGSPTPLEHECNDHSGDGDSSSDYVNNTSEEEDYDEGLPEEEEGITYYIRYCPEDDSYLEGMDCNGEEYAANEEHHIETDECQEAVEEWSEGKIQHQDENEVTDRQEWQEGQDNGIQVLEDEASSLEIQDQDENIQYCQSEGGYPDYYPAEANGNSQGISPYHSRKEDAELEEQEEDIDQIVAEIKMSMSMSSINSTTEMSPEHTGTENMAHDYKETCSKGEAVHSANRHEGRPKSLNIPSASKHGGDVPRGFKAKSRTPEDRQKWPQEQMCNGLEQPRKQQRSDLNGPVDNNNTPESKKVSSFPSFVDVPGPCEPEDLIDGIIFAANYLGSTQLLSERNPSKNIRMMQAQEAVSRVKTSEGDSQALTEVDLFISTQRIKVLNADTQETMMDHALRTISYIADIGNIVVLMARRRMPRSASQDCIETTPGAQEGKKQYKMICHVFESEDAQLIAQSIGQAFSVAYQEFLRANGINPEDLSQKEYSDIINTQEMYNDDLIHFSNSENCKELEKQKGEILGVVIVESGWGSILPTVILANMMNGGPAARSGKLSIGDQIMSINGTSLVGLPLATCQGIIKGLKNQTQVKLNIVSCPPVTTVLIKRPDLKYQLGFSVQNGIICSLMRGGIAERGGVRVGHRIIEINGQSVVATAHEKIVQALSNSVGEIHMKTMPAAMFRLLTGQETPLYI", "length": 741, "header": "tr|A0A8V1A4E8-1|A0A8V1A4E8_CHICK Computationally mapped isoform of Amyloid beta protein binding family A member 2 OS=Gallus gallus OX=9031 GN=APBA2 PE=4 SV=1 CANONICAL=F1NYK4-1" }, "locus": { "chromosome": "10", "start_pos": 5914614, "end_pos": 5876157, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010060584.1", "url": "https://www.ensembl.org/id/ENSGALT00010060584.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010037343.1", "url": "https://www.ensembl.org/id/ENSGALP00010037343.1" } ] } }, { "isoform_ac": "A0A8V1A7I9-1", "url": "https://www.uniprot.org/uniprotkb/F1NYK4/entry#A0A8V1A7I9-1", "sequence": { "sequence": "MANRKRQSTTASMLDHRARACPTSSHNREPENEESDLPVEDYPAKEAELATIRQGSPTPLEHECNDHSGDGDSSSDYVNNTSEEEDYDEGLPEEEEGITYYIRYCPEDDSYLEGMDCNGEEYAANEEHHIETDECQEAVEEWSEGKIQHQDENEVTDRQEWQEGQDNGIQVLEDEASSLEIQDQDENIQYCQSEGGYPDYYPAEANGNSQGISPYHSRKEDAELEEQEEDIDQIVAEIKMSMSMSSINSTTEMSPEHTGTENMAHDYKETCSKGEAVHSANRHEGRPKSLNIPSASKHGGDVPRGFKAKSRTPEDRQKWPQEQMCNGLEQPRKQQRSDLNGPVDNNNTPESKKVSSFPSFVDGPCEPEDLIDGIIFAANYLGSTQLLSERNPSKNIRMMQAQEAVSRVKTSEGDSQALTEVDLFISTQRIKVLNADTQETMMDHALRTISYIADIGNIVVLMARRRMPRSASQDCIETTPGAQEGKKQYKMICHVFESEDAQLIAQSIGQAFSVAYQEFLRANGINPEDLSQKEYSDIINTQEMYNDDLIHFSNSENCKELQLEKQKGEILGVVIVESGWGSILPTVILANMMNGGPAARSGKLSIGDQIMSINGTSLVGLPLATCQGIIKGLKNQTQVKLNIVSCPPVTTVLIKRPDLKYQLGFSVQNGIHSLIKALIFLLLCRIYLDYMVVDLSTV", "length": 698, "header": "tr|A0A8V1A7I9-1|A0A8V1A7I9_CHICK Computationally mapped isoform of Amyloid beta protein binding family A member 2 OS=Gallus gallus OX=9031 GN=APBA2 PE=4 SV=1 CANONICAL=F1NYK4-1" }, "locus": { "chromosome": "10", "start_pos": 5907326, "end_pos": 5876157, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010060567.1", "url": "https://www.ensembl.org/id/ENSGALT00010060567.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010037326.1", "url": "https://www.ensembl.org/id/ENSGALP00010037326.1" } ] } }, { "isoform_ac": "A0A8V1A7J4-1", "url": "https://www.uniprot.org/uniprotkb/F1NYK4/entry#A0A8V1A7J4-1", "sequence": { "sequence": "MANRKRQSTTASMLDHRARACPTSSHNREPENEESDLPVEDYPAKEAELATIRQGSPTPLEHECNDHSGDGDSSSDYVNNTSEEEDYDEGLPEEEEGITYYIRYCPEDDSYLEGMDCNGEEYAANEEHHIETDECQEAVEEWSEGKIQHQDENEVTDRQEWQEGQDNGIQVLEDEASSLEIQDQDENIQYCQSEGGYPDYYPAEANGNSQGISPYHSRKEDAELEEQEEDIDQIVAEIKMSMSMSSINSTTEMSPEHTGTENMAHDYKETCSKGEAVHSANRHEGRPKSLNIPSASKHGGDVPRGFKAKSRTPEDRQKWPQEQMCNGLEQPRKQQRSDLNGPVDNNNTPESKKVSSFPSFVDVPGPCEPEDLIDGIIFAANYLGSTQLLSERNPSKNIRMMQAQEAVSRVKTSEGDSQALTEVDLFISTQRIKVLNADTQAQLIAQSIGQAFSVAYQEFLRANGINPEDLSQKEYSDIINTQEMYNDDLIHFSNSENCKELQLEKQKGEILGVVIVESGWGSILPTVILANMMNGGPAARSGKLSIGDQIMSINGTSLVGLPLATCQGIIKGLKNQTQVKLNIVSCPPVTTVLIKRPDLKYQLGFSVQNGIICSLMRGGIAERGGVRVGHRIIEINGQSVVATAHEKIVQALSNSVGEIHMKTMPAAMFRLLTGQETPLYI", "length": 681, "header": "tr|A0A8V1A7J4-1|A0A8V1A7J4_CHICK Computationally mapped isoform of Amyloid beta protein binding family A member 2 OS=Gallus gallus OX=9031 GN=APBA2 PE=4 SV=1 CANONICAL=F1NYK4-1" }, "locus": { "chromosome": "10", "start_pos": 5914614, "end_pos": 5876157, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010060572.1", "url": "https://www.ensembl.org/id/ENSGALT00010060572.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010037331.1", "url": "https://www.ensembl.org/id/ENSGALP00010037331.1" } ] } }, { "isoform_ac": "F1NYK4-1", "url": "https://www.uniprot.org/uniprotkb/F1NYK4/entry#F1NYK4-1", "sequence": { "sequence": "MANRKRQSTTASMLDHRARACPTSSHNREPENEESDLPVEDYPAKEAELATIRQGSPTPLEHECNDHSGDGDSSSDYVNNTSEEEDYDEGLPEEEEGITYYIRYCPEDDSYLEGMDCNGEEYAANEEHHIETDECQEAVEEWSEGKIQHQDENEVTDRQEWQEGQDNGIQVLEDEASSLEIQDQDENIQYCQSEGGYPDYYPAEANGNSQGISPYHSRKEDAELEEQEEDIDQIVAEIKMSMSMSSINSTTEMSPEHTGTENMAHDYKETCSKGEAVHSANRHEGRPKSLNIPSASKHGGDVPRGFKAKSRTPEDRQKWPQEQMCNGLEQPRKQQRSDLNGPVDNNNTPESKKVSSFPSFVDVPGPCEPEDLIDGIIFAANYLGSTQLLSERNPSKNIRMMQAQEAVSRVKRMQKAAKIKKKATSEGDSQALTEVDLFISTQRIKVLNADTQETMMDHALRTISYIADIGNIVVLMARRRMPRSASQDCIETTPGAQEGKKQYKMICHVFESEDAQLIAQSIGQAFSVAYQEFLRANGINPEDLSQKEYSDIINTQEMYNDDLIHFSNSENCKELQLEKQKGEILGVVIVESGWGSILPTVILANMMNGGPAARSGKLSIGDQIMSINGTSLVGLPLATCQGIIKGLKNQTQVKLNIVSCPPVTTVLIKRPDLKYQLGFSVQNGIICSLMRGGIAERGGVRVGHRIIEINGQSVVATAHEKIVQALSNSVGEIHMKTMPAAMFRLLTGQETPLYI", "length": 755, "header": "tr|F1NYK4-1|F1NYK4_CHICK Isoform 1 of Amyloid beta protein binding family A member 2 OS=Gallus gallus OX=9031 GN=APBA2 PE=4 SV=2 CANONICAL=F1NYK4-1" }, "locus": { "chromosome": "10", "start_pos": 5914614, "end_pos": 5876157, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010060575.1", "url": "https://www.ensembl.org/id/ENSGALT00010060575.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010037334.1", "url": "https://www.ensembl.org/id/ENSGALP00010037334.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:415386", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:415386", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A061IBE0-1", "protein_name": "Amyloid-beta A4 precursor protein-binding family A member 2 isoform X1", "gene_name": "Apba2", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAHRKRQSTSSSMLDHRTRPGPIPHDQEPDSEDTELPLESYVPTGLELETLRPESPTPEEQECHNHSPDGDSSSDYVNNTSEEEDYDEGLPEEEEGVTYYIRYCPEDDSYLEGMDCNGEEYIAHGAHPVDTDECQEAVEEWTDSVGPHAHSHGAENSQEYPDSHLPIPEDDPSALEVHDQEEDGHYCPNKENYQDYYPTEANGNTGGASPYRMRRGDGDLEDQEEDIDQIVAEIKMSLSMTSITSASEASPEHMPELDPGDSTEACPPSESGHGPNRHEARPKSLNLPPEAKHAGDPQRGLKTKTRTPEERPKWPQEQVCNGLEQPRKQQRSDLNGPTDNNNIPETKKVASFPSFVAVPGPCEPEDLIDGIIFAANYLGSTQLLSERNPSKNIRMMQAQEAVSRVKRMQKAAKIKKKASSEGDAQTLTEVDLFISTQRIKVLNADTQETMMDHALRTISYIADIGNIVVLMARRRMPRSASQDCIETTPGAQEGKKQYKMICHVFESEDAQLIAQSIGQAFSVAYQEFLRANGINPEDLSQKEYSDIINTQEMYNDDLIHFSNSENCKELQLEKHKGEILGVVVVESGWGSILPTVILANMMNGGPAARSGKLSIGDQIMSINGTSLVGLPLATCQGIIKGLKNQTQVKLNIVSCPPVTTVLIKRPDLKYQLGFSVQNGIICSLMRGGIAERGGVRVGHRIIEINGQSVVATAHEKIVQALSNSVGEIHMKTMPAAMFRLLTGQETPLYI", "length": 750 }, "evidence": [ { "id": "F1NYK4", "url": "https://omabrowser.org/oma/group/F1NYK4/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "F1MLB6-1", "protein_name": "Amyloid beta protein binding family A member 2", "gene_name": "APBA2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MNGQRNILIICFRVISDHLIRIRISSLSKKDFITRRVFRTLPNCLFLWLPPGDDGCMSPTMAHRKRQSVASSLLDHRARPGPEPESEDAELALEEYVPTDLELAALRPESPVPAEQGGPDQSPDGDSSSDYVNNTSEEEDYDEGLPEEEEGITYYIRYCPEDDSYLQGTDCDGQGYLAHDTRHLETDECQEAVEEWTEPTGPHAHGHSDPGSPGYRDGHLSVPEDEASVLDSRDQEEDVHYCPSEEAYQDYYPAEANGNAGSTSPYRPRRRDGDPEDQEEDIDQIVAEIKMSLSMSSITSGGEASPEHAPRGPEPGPGDSPEACPLAEASRGPNRHEGRPKSLNLPPEAKHPADPQRSFKTKTRTPEERPKWPQEEVCNGLEQPRKQQRSDLNGPVDNNNIPETKKVASFPSFVAVPGPCEPEDLIDGIIFAANYLGSTQLLSERNPSKNIRMMQAQEAVSRVKNSEGDAQTLTEVDLFISTQRIKVLNADTQETMMDHALRTISYIADIGNIVVLMARRRMPRSASQDCIETTPGAQEGKKQYKMICHVFESEDAQLIAQSIGQAFSVAYQEFLRANGINPEDLSQKEYSDIINTQEMYNDDLIHFSNSENCKELQLEKHKGEILGVVVVESGWGSILPTVILANMMNGGPAARSGKLSIGDQIMSINGTSLVGLPLATCQGIIKGLKNQTQVKLNIVSCPPVTTVLIKRPDLKYQLGFSVQNGIICSLMRGGIAERGGVRVGHRIIEINGQSVVATAHEKIVQALSNSVGEIHMKTMPAAMFRLLTGQETPLYI", "length": 796 }, "evidence": [ { "id": "F1NYK4", "url": "https://omabrowser.org/oma/group/F1NYK4/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q99767-1", "protein_name": "Amyloid-beta A4 precursor protein-binding family A member 2", "gene_name": "APBA2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAHRKLESVGSGMLDHRVRPGPVPHSQEPESEDMELPLEGYVPEGLELAALRPESPAPEEQECHNHSPDGDSSSDYVNNTSEEEDYDEGLPEEEEGITYYIRYCPEDDSYLEGMDCNGEEYLAHSAHPVDTDECQEAVEEWTDSAGPHPHGHEAEGSQDYPDGQLPIPEDEPSVLEAHDQEEDGHYCASKEGYQDYYPEEANGNTGASPYRLRRGDGDLEDQEEDIDQIVAEIKMSLSMTSITSASEASPEHGPEPGPEDSVEACPPIKASCSPSRHEARPKSLNLLPEAKHPGDPQRGFKPKTRTPEERLKWPHEQVCNGLEQPRKQQRSDLNGPVDNNNIPETKKVASFPSFVAVPGPCEPEDLIDGIIFAANYLGSTQLLSERNPSKNIRMMQAQEAVSRVKRMQKAAKIKKKANSEGDAQTLTEVDLFISTQRIKVLNADTQETMMDHALRTISYIADIGNIVVLMARRRMPRSASQDCIETTPGAQEGKKQYKMICHVFESEDAQLIAQSIGQAFSVAYQEFLRANGINPEDLSQKEYSDIINTQEMYNDDLIHFSNSENCKELQLEKHKGEILGVVVVESGWGSILPTVILANMMNGGPAARSGKLSIGDQIMSINGTSLVGLPLATCQGIIKGLKNQTQVKLNIVSCPPVTTVLIKRPDLKYQLGFSVQNGIICSLMRGGIAERGGVRVGHRIIEINGQSVVATAHEKIVQALSNSVGEIHMKTMPAAMFRLLTGQETPLYI", "length": 749 }, "evidence": [ { "id": "F1NYK4", "url": "https://omabrowser.org/oma/group/F1NYK4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1NYK4", "url": "https://www.uniprot.org/uniprotkb/F1NYK4" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "F1NYK4", "url": "https://www.uniprot.org/uniprotkb/F1NYK4" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F1NYK4", "url": "https://www.uniprot.org/uniprotkb/F1NYK4" } ], "pmid": "" }, { "name": "dendritic spine", "id": "GO:0043197", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043197", "evidence": [ { "database": "UniProtKB", "id": "F1NYK4", "url": "https://www.uniprot.org/uniprotkb/F1NYK4" } ], "pmid": "" }, { "name": "presynapse", "id": "GO:0098793", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098793", "evidence": [ { "database": "UniProtKB", "id": "F1NYK4", "url": "https://www.uniprot.org/uniprotkb/F1NYK4" } ], "pmid": "" }, { "name": "Schaffer collateral - CA1 synapse", "id": "GO:0098685", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098685", "evidence": [ { "database": "UniProtKB", "id": "F1NYK4", "url": "https://www.uniprot.org/uniprotkb/F1NYK4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "F1NYK4", "url": "https://www.uniprot.org/uniprotkb/F1NYK4" } ], "pmid": "" }, { "name": "amyloid-beta binding", "id": "GO:0001540", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001540", "evidence": [ { "database": "UniProtKB", "id": "F1NYK4", "url": "https://www.uniprot.org/uniprotkb/F1NYK4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "chemical synaptic transmission", "id": "GO:0007268", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007268", "evidence": [ { "database": "UniProtKB", "id": "F1NYK4", "url": "https://www.uniprot.org/uniprotkb/F1NYK4" } ], "pmid": "" }, { "name": "presynaptic modulation of chemical synaptic transmission", "id": "GO:0099171", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099171", "evidence": [ { "database": "UniProtKB", "id": "F1NYK4", "url": "https://www.uniprot.org/uniprotkb/F1NYK4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 248, "end_pos": 250, "annotation": "n_glycosylation_sequon" }, { "start_pos": 346, "end_pos": 348, "annotation": "n_glycosylation_sequon" }, { "start_pos": 628, "end_pos": 630, "annotation": "n_glycosylation_sequon" }, { "start_pos": 649, "end_pos": 651, "annotation": "n_glycosylation_sequon" }, { "start_pos": 79, "end_pos": 81, "annotation": "n_glycosylation_sequon" }, { "start_pos": 80, "end_pos": 82, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1NYK4-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 755, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1NYK4-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1NYK4" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 248, "end_pos": 250 }, { "start_pos": 346, "end_pos": 348 }, { "start_pos": 628, "end_pos": 630 }, { "start_pos": 649, "end_pos": 651 }, { "start_pos": 79, "end_pos": 81 }, { "start_pos": 80, "end_pos": 82 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1NY54-1", "uniprot_ac": "F1NY54", "uniprot_id": "F1NY54_CHICK", "mass": { "chemical_mass": 109881.0, "monoisotopic_mass": 109881.0 }, "refseq": { "ac": "NP_001292594", "name": "thyroid hormone receptor-associated protein 3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001292594" }, "gene_names": [ { "name": "THRAP3", "type": "recommended", "evidence": [ { "id": "F1NY54", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NY54" } ] }, { "name": "THRAP3", "type": "synonym", "evidence": [ { "id": "NP_001292594", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001292594" } ] } ], "protein_names": [ { "name": "Thyroid hormone receptor associated protein 3", "type": "synonym", "evidence": [ { "id": "F1NY54", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NY54/entry#names_and_taxonomy" } ] }, { "name": "thyroid hormone receptor-associated protein 3", "type": "synonym", "evidence": [ { "id": "NP_001292594", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001292594" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: SRR13267655.33304.1, SRR13267659.291433.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA103992290, SAMEA103992323 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000339.1. On Nov 25, 2021 this sequence version replaced XP_015153144.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001292594", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001292594" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NY54", "url": "https://www.uniprot.org/uniprotkb/F1NY54" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "THRAP3", "url": "https://www.uniprot.org/uniprotkb/F1NY54", "locus": { "chromosome": "23", "start_pos": 4419217, "end_pos": 4441257, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010014795", "url": "https://www.ensembl.org/id/ENSGALG00010014795" } ] } } ], "crossref": [ { "id": "F1NY54", "url": "https://alphafold.ebi.ac.uk/entry/F1NY54", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000002144", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000002144", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "419623", "url": "https://www.ncbi.nlm.nih.gov/gene/419623", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR029199", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029199", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:419623", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419623", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "GEGTDKW", "url": "https://omabrowser.org/oma/group/GEGTDKW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q2UGA1", "url": "https://www.orthodb.org/?gene=A0A3Q2UGA1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NY54", "url": "https://www.orthodb.org/?gene=F1NY54", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15268", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15268", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15268:SF16", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15268:SF16", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15440", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15440", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001292594", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001292594", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q2UGA1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UGA1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2UGA1-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UGA1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NY54", "url": "https://www.uniprot.org/uniprotkb/F1NY54", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NY54-1", "url": "https://www.uniprot.org/uniprotkb/F1NY54-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSKTNKSKSGSRSSRSRSGSRSRSRSFSKSRSRSRSVSRSRKRRLSSRSRSRSYSPSHNRERNHPRVYQNRDFRGHNRGYRRPYYFRGRNRGFYPWGQYNRGGYGNYRSNWQNYRQAYSPRRGRSRSRSPKRRSPSPRSRSHSRNSDKSSSDRSRRSSSSRSSSNHSRVESSKRKSGKEKKSSSKEARASQAAGDNQGDDSKEQPFSGAAAQDAKASEGSKPWQDVSTYGSSSTSRAAAPELSPRERSPALKSPLQSVVVRRRSPRPSPLQKSSSPLSNPSQMSSASQSSTSFQAGSHQSPFDHGSSGLSPTRKSPVCKSPTPISSMYGTSQKEETTAPGGGAFSKRYLEEQKAENGKDKDQKVTNVEKEKNKEKGNFSEVGSTDGKAKSDSYASKADSEKGYRGSQSPKRYKFRDDFDKPKAPEFHKESHYGKDETDDQEKKEKAKGRKDSDFDDEPKFMSKVVATSSKSQEEDRQGKWEGVVFLPPGKEKQRKSEEMEEESYSERSKKEERPASKRSEPGHRGFVPEKNFRVTTYKTSQEKSSSPPPRKASEVKEKPGSKGDGLAPGKSSFSITREAQVNIRMDSFDEDLARPSGILAQERKLCRDLVHSNKKEQEFRSIFHHIQSAQSQRSPSELFAQHIVTIVHHVREHHFGSSGMTLNERFTKYLKKGMEQEAAKNKKSPEIHRRIDISPSTFRKHGFSQEESKSSRDPGFKAEGKYKDDPVDLRLDIERRKKHKERDLKRDKSRESVESRDSSHSRERSAEKTEKSHKSSKKKKHRRVRERSRSSSSSSRSSHSVKAEEYPEETEEREESTTGFDKSRLGTKEFTGPNERGRARGTFQFRARGRGWGRGNFSGNNNSNSGGNNDFQKRSREEDWDPEYTPKSKKYYLHDDREGEGAEKWVSRGRGRGAFPRGRGRFMFRKSSTSPKWAHDKFSGEEGEIEDDESGTENREDKDSLQSAAE", "length": 966, "header": "tr|F1NY54-1|F1NY54_CHICK Isoform 1 of Thyroid hormone receptor associated protein 3 OS=Gallus gallus OX=9031 GN=THRAP3 PE=1 SV=2 CANONICAL=F1NY54-1" }, "isoforms": [ { "isoform_ac": "A0A3Q2UGA1-1", "url": "https://www.uniprot.org/uniprotkb/F1NY54/entry#A0A3Q2UGA1-1", "sequence": { "sequence": "MSKTNKSKSGSRSSRSRSGSRSRSRSFSKSRSRSRSVSRSRKRRLSSRSRSRSYSPSHNRERNHPRVYQNRDFRGHNRGYRRPYYFRGRNRGFYPWGQYNRGGYGNYRSNWQNYRQAYSPRRGRSRSRSPKRRSPSPRSRSHSRNSDKSSSDRSRRSSSSRSSSNHSRVESSKRKSGKEKKSSSKEARASQAAGDNQGDDSKEQPFSGAAAQDAKASEGSKPWQDVSTYGSSSTSRAAAPELSPRERSPALKSPLQSVVVRRRSPRPSPLQKSSSPLSNPSQMSSASQSSTSFQAGSHQSPFDHGSSGLSPTRKSPVCKSPTPISSMYGTSQKEETTAPGGGAFSKRYLEEQKAENGKDKDQKVTNVEKEKNKEKGNFSEVGSTDGKAKSDSYASKADSEKGYRGSQSPKRYKFRDDFDKPKAPEFHKESHYGKDETDDQEKKEKAKGRKDSDFDDEPKFMSKVVATSSKSQEEDRQGKWEGVVFLPPGKEKQRKSEEMEEESYSERSKKEERPASKRSEPGHRGFVPEKNFRVTTYKTSQEKSSSPPPRKASEVKEKPGSKGDGLAPGKSSFSITREAQVNIRMDSFDEDLARPSGILAQERKLCRDLVHSNKKEQEFRSIFHHIQSAQSQRSPSELFAQHIVTIVHHVREHHFGSSGMTLNERFTKYLKKGMEQEAAKNKKSPEIHRRIDISPSTFRKHGFSQEESKSSRDPGFKDGHNSKNELQRVNFY", "length": 732, "header": "tr|A0A3Q2UGA1-1|A0A3Q2UGA1_CHICK Computationally mapped isoform of Thyroid hormone receptor associated protein 3 OS=Gallus gallus OX=9031 GN=THRAP3 PE=1 SV=1 CANONICAL=F1NY54-1" }, "locus": { "chromosome": "23", "start_pos": 4432239, "end_pos": 4424885, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010035589.1", "url": "https://www.ensembl.org/id/ENSGALT00010035589.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020663.1", "url": "https://www.ensembl.org/id/ENSGALP00010020663.1" } ] } }, { "isoform_ac": "F1NY54-1", "url": "https://www.uniprot.org/uniprotkb/F1NY54/entry#F1NY54-1", "sequence": { "sequence": "MSKTNKSKSGSRSSRSRSGSRSRSRSFSKSRSRSRSVSRSRKRRLSSRSRSRSYSPSHNRERNHPRVYQNRDFRGHNRGYRRPYYFRGRNRGFYPWGQYNRGGYGNYRSNWQNYRQAYSPRRGRSRSRSPKRRSPSPRSRSHSRNSDKSSSDRSRRSSSSRSSSNHSRVESSKRKSGKEKKSSSKEARASQAAGDNQGDDSKEQPFSGAAAQDAKASEGSKPWQDVSTYGSSSTSRAAAPELSPRERSPALKSPLQSVVVRRRSPRPSPLQKSSSPLSNPSQMSSASQSSTSFQAGSHQSPFDHGSSGLSPTRKSPVCKSPTPISSMYGTSQKEETTAPGGGAFSKRYLEEQKAENGKDKDQKVTNVEKEKNKEKGNFSEVGSTDGKAKSDSYASKADSEKGYRGSQSPKRYKFRDDFDKPKAPEFHKESHYGKDETDDQEKKEKAKGRKDSDFDDEPKFMSKVVATSSKSQEEDRQGKWEGVVFLPPGKEKQRKSEEMEEESYSERSKKEERPASKRSEPGHRGFVPEKNFRVTTYKTSQEKSSSPPPRKASEVKEKPGSKGDGLAPGKSSFSITREAQVNIRMDSFDEDLARPSGILAQERKLCRDLVHSNKKEQEFRSIFHHIQSAQSQRSPSELFAQHIVTIVHHVREHHFGSSGMTLNERFTKYLKKGMEQEAAKNKKSPEIHRRIDISPSTFRKHGFSQEESKSSRDPGFKAEGKYKDDPVDLRLDIERRKKHKERDLKRDKSRESVESRDSSHSRERSAEKTEKSHKSSKKKKHRRVRERSRSSSSSSRSSHSVKAEEYPEETEEREESTTGFDKSRLGTKEFTGPNERGRARGTFQFRARGRGWGRGNFSGNNNSNSGGNNDFQKRSREEDWDPEYTPKSKKYYLHDDREGEGAEKWVSRGRGRGAFPRGRGRFMFRKSSTSPKWAHDKFSGEEGEIEDDESGTENREDKDSLQSAAE", "length": 966, "header": "tr|F1NY54-1|F1NY54_CHICK Isoform 1 of Thyroid hormone receptor associated protein 3 OS=Gallus gallus OX=9031 GN=THRAP3 PE=1 SV=2 CANONICAL=F1NY54-1" }, "locus": { "chromosome": "23", "start_pos": 4432239, "end_pos": 4420384, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010035595.1", "url": "https://www.ensembl.org/id/ENSGALT00010035595.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020666.1", "url": "https://www.ensembl.org/id/ENSGALP00010020666.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:419623", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419623", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3Q1NI32-1", "protein_name": "Thyroid hormone receptor associated protein 3", "gene_name": "THRAP3", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSKTNKSKSGSRSSRSRSASRSRSRSFSKSRSRSRSVSRSRKRRLSSRSRSRSYSPAHNRERNHPRVYQNRDFRGHNRGYRRPYYFRGRNRGFYPWGQYNRGGYGNYRSNWQNYRQAYSPRRGRSRSRSPKRRSPSPRSRSHSRNSDKSSSDRSRRSSSSRSSSNHSRVESSKRKSAKEKKSSSKDSRPSQAAGDNQGDEAKEQPFSGGTSQDPKASESSKPWPDATTYSAGSASRASGVSELSPRERSPALKSPLQSVVVRRRSPRPSPVPKPSPPLSSTSQMGSTLQSGAGYQGGTHQGQFDHGSGSLSPSKKSPVGKSPPATGSTYGSSQKEEAAAPGGAAYTKRYLDEQKTENGKDKEQKQTNTDKEKMKEKGSFSDTGLGDTKMKSDSFAPKTDTEKPFRGSQSPKRYKLRDDFEKKMADFHKEEMDDQDKDKAKGRKESEFDDEPKFMSKVIAGASKNQEEEKSGKWEGLVYAPPGKEKQRKTEELEEESFSERSKKEERGGSKRSESGHRGFVPEKNFRVTAYKAVQEKSSSPPPRKTSESREKLGAKGDFSTGKSSFSITREAQVNVRMDSFDEDLARPSGLLAQERKLCRDLVHSNKKEQEFRSIFQHIQSAQSQRSPSELFAQHIVTIVHHVKEHHFGSSGMTLHERFTKYLKRGSEQEAAKNKKSPEIHRRIDISPSTFRKHGLAHDEMKSPREPGYKAEGKYKDDPVDLRLDIERRKKHKERDLKRGKSRESVDSRDSSHSRERSAEKTEKTHKGSKKQKKHRRARDRSRSSSSSSQSSHSYKAEEYTEETEEREESTTGFDKSRLGTKDFVGPSERGGRARGTFQFRARGRGWGRGNYSGNNNNSSNNDFQKRSREEEWDPEYTPKSKKYYLHDDREGEGSEKWVSRGRGRGAFPRGRGRFMFRKSSTSPKWAHDKFSGEEGEIEDDESGTENREEKDNLQPTTE", "length": 958 }, "evidence": [ { "id": "F1NY54", "url": "https://omabrowser.org/oma/group/F1NY54/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A4X1VYM7-1", "protein_name": "Thyroid hormone receptor associated protein 3", "gene_name": "THRAP3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSKTNKSKSGSRSSRSRSASRSRSRSFSKSRSRSRSVSRSRKRRLSSRSRSRSYSPAHNRERNHPRVYQNRDFRGHNRGYRRPYYFRGRNRGFYPWGQYNRGGYGNYRSNWQNYRQAYSPRRGRSRSRSPKRRSPSPRSRSHSRNSDKSSSDRSRRSSSSRSSSNHSRVESSKRKSTKEKKSSSKDSRPSQAAGDNQGDEAKDQTFSGGTSQDTKASESSKPWPDATTYSAGSTSRASAVSEMSPRERSPALKSPLQSVVVRRRSPRPSPVPKPSPPLSSTSQMGSTLQSGAGYQAGTHQGQFDHGSGSLSPSKKSPVGKSPPATGSTYGSSQKEEGAAPGGAAYTKRYLDEQKTENGKDKEQKQTNTDKEKMKEKGSFSDAGLGDTKVKSDPFAPKTDTEKPFRGSQSPKRYKLRDDFEKKMADFHKEELDDQDKDKAKGRKESEFDDEPKYMSKVIAGTNKNQEEEKSGKWEGLVYAPPGKEKQRKTEELEEESFSERSKKEDRGGPKRTESGHRGFVPEKNFRVTAYKAVQEKSSSPPPRKTSESREKLGAKGDFSTGKSSFSITREAQVNVRMDSFDEDLARPSGLLAQERKLCRDLVHSNKKEQEFRSIFQHIQSAQSQRSPSELFAQHIVTIVHHVKEHHFGSSGMTLHERFTKYLKRGTEQEAAKNKKSPEIHRRIDISPSTFRKHGLAHDEMKSPREPGYKAEGKYKDDPVDLRLDIERRKKHKERDLKRGKSRESVDSRDSSHSRERSAEKTEKTHKGSKKQKKHRRARDRSRSSSSSSQSSHSYKAEEYTEETEEREESTTGFDKSRLGTKDFVGPSERGGRARGTFQFRARGRGWGRGNYSGNNNNSSNNDFQKRNREEEWDPEYTPKSKKYYLHDDREGEGSEKWVSRGRGRGAFPRGRGRFMFRKSSTSPKWAHDKFSGEEGEIEDDESGTENREEKDNLQPTTE", "length": 958 }, "evidence": [ { "id": "F1NY54", "url": "https://omabrowser.org/oma/group/F1NY54/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0AB32TCL0-1", "protein_name": "Thyroid hormone receptor-associated protein 3b isoform X1", "gene_name": "thrap3b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MADLLTHSVQKTTLGYAEMSKPPNSASRSRSRSRSRTRSRTYSRSHSRSRSRSRSRKRRYSSRSRSRSHSRERNYPSRDFQGNRGYNRGFRGYRRPFQYNRGRGRGFFPRGNYHRGGSNYGYRSNNWHGHRDQQQPYDHSYSPRRGRSRSHSPRKRSPSRSRSRHSNRSSSGRSRRSSSSSHSRSPRPRNSSTGRPHSKDGKDRGSPGESKGAAKEASKPTGSPPEESGKWEGMTDYDASPKRTAASAGPSDIKVSLSGNSGNGGSLWRSIGPASKSPPAKTSTSTGFGFFSKEDMKTEDKSASISTAFKKFLAEKKKPSDRDNGRGESLSLGEADNEKSGSKSRSTFNTSDSPYDGSKTDKVLPFLDPEEEEYRQELKERKAEEETKYKEKTLVTMRDLTEERFGKWDDSVYLSSKESSRRDEDVEEELDEELYRSRKHASRKEEKAAKKKEKKKSRISCSPSSPPSSGGRPLFPVVREASPPVKSSAKKEPQFNFSIKAFTGDGEGSSGALTKERRLSRDLVHPGKKDQDDFRSIFQHIQSAQLRRSPSELFAQHIVTIVHHIKAQHFKSSGMTLNERFGIYQRKAAEVEMMKPKKSPEIHRRIDVSPSAFKKHSQMFEDFEESGYKDHGKRHEGDSLDLRLAIERRKKDPKREGGKSSAGSRTPSHELSPERSSKQKKSKKSKKKRERSPSSSSSSSSSPSPRPYRGKEYSEEHMEGGFNKARLGSRDYPGPMERGPRDYEGYMERGYERDRGGYDRGGYDRGRGGYDRGFPRMRGRGWNRGNYPGNNPNINPPNMGGPPRPPDEEWDPEYTPKSRKYFQHDDRDKEGEMKWLDTRGRGRGNFPRARGTFMVRKSGGSPKWTHDMFQGNMEEGEIEGGSEHKDEDKPGENPASKP", "length": 898 }, "evidence": [ { "id": "F1NY54", "url": "https://omabrowser.org/oma/group/F1NY54/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q569Z6-1", "protein_name": "Thyroid hormone receptor-associated protein 3", "gene_name": "Thrap3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSKTNKSKSGSRSSRSRSASRSRSRSFSKSRSRSRSVSRSRKRRLSSRSRSRSYSPAHNRERNHPRVYQNRDFRGHNRGYRRPYYFRGRNRGFYPWGQYNRGGYGNYRSNWQNYRQAYSPRRGRSRSRSPKRRSPSPRSRSHSRNSDKSSSDRSRRSSSSRSSSNHSRVESSKRKSTKEKKSSSKDSRPSQAAGDNQGDEAKEQTFSGGTSQDIKGSESSKPWPDATTYGAGSASRASVSDLSPRERSPALKSPLQSVVVRRRSPRPSPVPKPSPPLSNASQMGSSMSGGAGYQSGAHQGQFDHGSGSLSPSKKSPVGKSPPATGSAYGSSQKEESAASGGAAYSKRYLEEQKTENGKDKEQKQTNADKEKLKEKGGFSDADVKMKSDPFAPKTDSEKPFRGSQSPKRYKLRDDFEKKMADFHKEELDEHDKDKSKGRKEPEFDDEPKFMSKVIAGASKNQEEEKSGKWESLHTGKEKQRKAEEMEDEPFTERSRKEERGGSKRSESGHRGFVPEKNFRVTAYKAVQEKSSSPPPRKTSESRDKLGSKGDFSSGKSSFSITREAQVNVRMDSFDEDLARPSGLLAQERKLCRDLVHSNKKEQEFRSIFQHIQSAQSQRSPSELFAQHIVTIVHHVKEHHFGSSGMTLHERFTKYLKRGNEQEAAKNKKSPEIHRRIDISPSTFRKHGLTHEELKSPREPGYKAEGKYKDDPVDLRLDIERRKKHKERDLKRGKSRESVDSRDSSHSRERSTEKTEKTHKGSKKQKKHRRARDRSRSSSSSSQSSHSYKAEEYPEEAEEREESTSGFDKSRLGTKDFVGPNERGGRARGTFQFRARGRGWGRGNYSGNNNNNSNNDFQKRSREEEWDPEYTPKSKKYYLHDDREGEGSDKWMGRGRGRGAFPRGRGRFMFRKSSTSPKWAHDKFSGEEGEIEDDESGTENREEKDSLQPSAE", "length": 951 }, "evidence": [ { "id": "F1NY54", "url": "https://omabrowser.org/oma/group/F1NY54/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q5M7V8-1", "protein_name": "Thyroid hormone receptor-associated protein 3", "gene_name": "Thrap3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSKTNKSKSGSRSSRSRSASRSRSRSFSKSRSRSRSVSRSRKRRLSSRSRSRSYSPAHNRERNHPRVYQNRDFRGHNRGYRRPYYFRGRNRGFYPWGQYNRGGYGNYRSNWQNYRQAYSPRRGRSRSRSPKRRSPSPRSRSHSRNSDKSSSDRSRRSSSSRSSSNHSRVESSKRKSTKEKKSSSKDSRPSQAAGDNQGDEAKEQTFSGGTSQDIKGSESSKPWPDATTYGTGSASRASVSDLSPRERSPALKSPLQSVVVRRRSPRPSPVPKPSPPLSNASQMGSSMSGGAGYQSGAHQGPFDHGSGSLSPSKKSPVGKSPPATGSAYGSSQKEESAASGGAAYTKRYLEEQKTENGKDKEQKQTNTDKEKLKEKGGFSDADVKMKSDPFAPKTDTEKPFRGSQSPKRYKLRDDFEKKMADFHKEEMDEQDKDKCKGRKEPEFDDEPKFISKVIAGASKNQEEEKSGKWESLHAGKEKQRKAEELEEEPFTERSRKEERGGSKRSESGHRGFVPEKNFRVTAYKAVQEKSSSPPPRKTSESRDKLGNKGDFSSGKSSFSITREAQVNVRMDSFDEDLARPSGLLAQERKLCRDLVHSNKKEQEFRSIFQHIQSAQSQRSPSELFAQHIVTIVHHVKEHHFGSSGMTLHERFTKYLKRGNEQEAAKTKKSPEIHRRIDISPSTFRKHGLTHEELKSPREPGYKAEGKYKDDPVDLRLDIERRKKHKERDLKRGKSRESVDSRDSSHSRERSTEKTEKTHKGSKKQKKHRRARDRSRSSSSSSQSSHSYKAEEYPEEAEDREESTTGFDKSRLGTKDFVGPNERGGRARGTFQFRARGRGWGRGNYSGNNNNNSNNDFQKRSREEEWDPEYTPKSKKYYLHDDREGEGSDKWMSRGRGRGAFPRGRGRFMFRKSSTSPKWAHDKFSGEEGEIEDDESGTENREEKDSLQPSAE", "length": 951 }, "evidence": [ { "id": "F1NY54", "url": "https://omabrowser.org/oma/group/F1NY54/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9Y2W1-1", "protein_name": "Thyroid hormone receptor-associated protein 3", "gene_name": "THRAP3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSKTNKSKSGSRSSRSRSASRSRSRSFSKSRSRSRSLSRSRKRRLSSRSRSRSYSPAHNRERNHPRVYQNRDFRGHNRGYRRPYYFRGRNRGFYPWGQYNRGGYGNYRSNWQNYRQAYSPRRGRSRSRSPKRRSPSPRSRSHSRNSDKSSSDRSRRSSSSRSSSNHSRVESSKRKSAKEKKSSSKDSRPSQAAGDNQGDEAKEQTFSGGTSQDTKASESSKPWPDATYGTGSASRASAVSELSPRERSPALKSPLQSVVVRRRSPRPSPVPKPSPPLSSTSQMGSTLPSGAGYQSGTHQGQFDHGSGSLSPSKKSPVGKSPPSTGSTYGSSQKEESAASGGAAYTKRYLEEQKTENGKDKEQKQTNTDKEKIKEKGSFSDTGLGDGKMKSDSFAPKTDSEKPFRGSQSPKRYKLRDDFEKKMADFHKEEMDDQDKDKAKGRKESEFDDEPKFMSKVIGANKNQEEEKSGKWEGLVYAPPGKEKQRKTEELEEESFPERSKKEDRGKRSEGGHRGFVPEKNFRVTAYKAVQEKSSSPPPRKTSESRDKLGAKGDFPTGKSSFSITREAQVNVRMDSFDEDLARPSGLLAQERKLCRDLVHSNKKEQEFRSIFQHIQSAQSQRSPSELFAQHIVTIVHHVKEHHFGSSGMTLHERFTKYLKRGTEQEAAKNKKSPEIHRRIDISPSTFRKHGLAHDEMKSPREPGYKAEGKYKDDPVDLRLDIERRKKHKERDLKRGKSRESVDSRDSSHSRERSAEKTEKTHKGSKKQKKHRRARDRSRSSSSSSQSSHSYKAEEYTEETEEREESTTGFDKSRLGTKDFVGPSERGGGRARGTFQFRARGRGWGRGNYSGNNNNNSNNDFQKRNREEEWDPEYTPKSKKYYLHDDREGEGSDKWVSRGRGRGAFPRGRGRFMFRKSSTSPKWAHDKFSGEEGEIEDDESGTENREEKDNIQPTTE", "length": 955 }, "evidence": [ { "id": "F1NY54", "url": "https://omabrowser.org/oma/group/F1NY54/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 7, "go_terms": [ { "name": "positive regulation of mRNA splicing, via spliceosome", "id": "GO:0048026", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048026", "evidence": [ { "database": "UniProtKB", "id": "F1NY54", "url": "https://www.uniprot.org/uniprotkb/F1NY54" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "F1NY54", "url": "https://www.uniprot.org/uniprotkb/F1NY54" } ], "pmid": "" }, { "name": "mRNA stabilization", "id": "GO:0048255", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048255", "evidence": [ { "database": "UniProtKB", "id": "F1NY54", "url": "https://www.uniprot.org/uniprotkb/F1NY54" } ], "pmid": "" }, { "name": "circadian rhythm", "id": "GO:0007623", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007623", "evidence": [ { "database": "UniProtKB", "id": "F1NY54", "url": "https://www.uniprot.org/uniprotkb/F1NY54" } ], "pmid": "" }, { "name": "nuclear-transcribed mRNA catabolic process", "id": "GO:0000956", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000956", "evidence": [ { "database": "UniProtKB", "id": "F1NY54", "url": "https://www.uniprot.org/uniprotkb/F1NY54" } ], "pmid": "" }, { "name": "positive regulation of circadian rhythm", "id": "GO:0042753", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042753", "evidence": [ { "database": "UniProtKB", "id": "F1NY54", "url": "https://www.uniprot.org/uniprotkb/F1NY54" } ], "pmid": "" }, { "name": "regulation of alternative mRNA splicing, via spliceosome", "id": "GO:0000381", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000381", "evidence": [ { "database": "UniProtKB", "id": "F1NY54", "url": "https://www.uniprot.org/uniprotkb/F1NY54" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 6, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "F1NY54", "url": "https://www.uniprot.org/uniprotkb/F1NY54" } ], "pmid": "" }, { "name": "transcription coactivator activity", "id": "GO:0003713", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003713", "evidence": [ { "database": "UniProtKB", "id": "F1NY54", "url": "https://www.uniprot.org/uniprotkb/F1NY54" } ], "pmid": "" }, { "name": "phosphoprotein binding", "id": "GO:0051219", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051219", "evidence": [ { "database": "UniProtKB", "id": "F1NY54", "url": "https://www.uniprot.org/uniprotkb/F1NY54" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "F1NY54", "url": "https://www.uniprot.org/uniprotkb/F1NY54" } ], "pmid": "" }, { "name": "nuclear thyroid hormone receptor binding", "id": "GO:0046966", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046966", "evidence": [ { "database": "UniProtKB", "id": "F1NY54", "url": "https://www.uniprot.org/uniprotkb/F1NY54" } ], "pmid": "" }, { "name": "transcription coregulator activity", "id": "GO:0003712", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003712", "evidence": [ { "database": "UniProtKB", "id": "F1NY54", "url": "https://www.uniprot.org/uniprotkb/F1NY54" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nuclear speck", "id": "GO:0016607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016607", "evidence": [ { "database": "UniProtKB", "id": "F1NY54", "url": "https://www.uniprot.org/uniprotkb/F1NY54" } ], "pmid": "" }, { "name": "mediator complex", "id": "GO:0016592", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016592", "evidence": [ { "database": "UniProtKB", "id": "F1NY54", "url": "https://www.uniprot.org/uniprotkb/F1NY54" } ], "pmid": "" }, { "name": "exon-exon junction complex", "id": "GO:0035145", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035145", "evidence": [ { "database": "UniProtKB", "id": "F1NY54", "url": "https://www.uniprot.org/uniprotkb/F1NY54" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 165, "end_pos": 167, "annotation": "n_glycosylation_sequon" }, { "start_pos": 377, "end_pos": 379, "annotation": "n_glycosylation_sequon" }, { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" }, { "start_pos": 856, "end_pos": 858, "annotation": "n_glycosylation_sequon" }, { "start_pos": 861, "end_pos": 863, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1NY54-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 966, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1NY54-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1NY54" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 165, "end_pos": 167 }, { "start_pos": 377, "end_pos": 379 }, { "start_pos": 5, "end_pos": 7 }, { "start_pos": 856, "end_pos": 858 }, { "start_pos": 861, "end_pos": 863 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1NU16-1", "uniprot_ac": "F1NU16", "uniprot_id": "F1NU16_CHICK", "mass": { "chemical_mass": 88487.0, "monoisotopic_mass": 88487.0 }, "refseq": { "ac": "NP_001026643", "name": "splicing factor 3A subunit 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026643" }, "gene_names": [ { "name": "SF3A1", "type": "recommended", "evidence": [ { "id": "F1NU16", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NU16" } ] }, { "name": "SF3A1", "type": "synonym", "evidence": [ { "id": "NP_001026643", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026643" } ] } ], "protein_names": [ { "name": "Splicing factor 3A subunit 1", "type": "recommended", "evidence": [ { "id": "F1NU16", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NU16/entry#names_and_taxonomy" } ] }, { "name": "splicing factor 3A subunit 1", "type": "synonym", "evidence": [ { "id": "NP_001026643", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026643" } ] }, { "name": "splicing factor 3a, subunit 1, 120kDa", "type": "synonym", "evidence": [ { "id": "NP_001026643", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026643" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: SRR13267652.4899.1, SRR13267658.13383.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000260.1. On Mar 18, 2015 this sequence version replaced NP_001026643.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001026643", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026643" } ] }, { "annotation": "Component of the 17S U2 SnRNP complex of the spliceosome, a large ribonucleoprotein complex that removes introns from transcribed pre-mRNAs. The 17S U2 SnRNP complex (1) directly participates in early spliceosome assembly and (2) mediates recognition of the intron branch site during pre-mRNA splicing by promoting the selection of the pre-mRNA branch-site adenosine, the nucleophile for the first step of splicing. Within the 17S U2 SnRNP complex, SF3A1 is part of the SF3A subcomplex that contributes to the assembly of the 17S U2 snRNP, and the subsequent assembly of the pre-spliceosome 'E' complex and the pre-catalytic spliceosome 'A' complex. Involved in pre-mRNA splicing as a component of pre-catalytic spliceosome 'B' complexes.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0WZP4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0WZP4#function" }, { "database": "UniProtKB", "id": "ARBA00060058", "url": "https://www.uniprot.org/uniprotkb/ARBA00060058#function" }, { "database": "UniProtKB", "id": "A0A8V0X2H7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X2H7#function" }, { "database": "UniProtKB", "id": "F1NU16", "url": "https://www.uniprot.org/uniprotkb/F1NU16#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NU16", "url": "https://www.uniprot.org/uniprotkb/F1NU16" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SF3A1", "url": "https://www.uniprot.org/uniprotkb/F1NU16", "locus": { "chromosome": "15", "start_pos": 10844235, "end_pos": 10830649, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010000215", "url": "https://www.ensembl.org/id/ENSGALG00010000215" } ] } } ], "crossref": [ { "id": "F1NU16", "url": "https://alphafold.ebi.ac.uk/entry/F1NU16", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000007937", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000007937", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd01800", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01800", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "427717", "url": "https://www.ncbi.nlm.nih.gov/gene/427717", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000061", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000061", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000626", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000626", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR022030", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022030", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029071", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029071", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035563", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035563", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035967", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035967", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045146", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045146", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:427717", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427717", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HAYYRHR", "url": "https://omabrowser.org/oma/group/HAYYRHR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0WZP4", "url": "https://www.orthodb.org/?gene=A0A8V0WZP4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0X2H7", "url": "https://www.orthodb.org/?gene=A0A8V0X2H7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NU16", "url": "https://www.orthodb.org/?gene=F1NU16", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15316", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15316", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15316:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15316:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00240", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00240", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01805", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01805", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12230", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12230", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-9770562", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9770562", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001026643", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026643", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0WZP4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0WZP4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0WZP4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0WZP4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0X2H7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X2H7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0X2H7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X2H7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NU16", "url": "https://www.uniprot.org/uniprotkb/F1NU16", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NU16-1", "url": "https://www.uniprot.org/uniprotkb/F1NU16-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPAGPVQAGPPAQPAPPAESKPPEEEPKEEAAPAKPVVGIIYPPPEVRNIVDKTASFVARNGPEFEARIRQNEINNPKFNFLNPNDPYHAYYRHKVSEFKEGKAQEPSAAIPKVMQQQQTAQQQLPQKVQAQVIQETVVPKEPPPEFEFIADPPSISAFDLDVVKLTAQFVARNGRQFLTQLMQKEQRNYQFDFLRPQHSLFNYFTKLVEQYTKILIPPKGLLIKLKKEAENPKEVLDQVYYRVEWAKFQERERKKEEEEKEKERVAYAQIDWHDFVVVETVDFQPNEQGNFPPPTTPEELGARILIQERYEKFGESEEVEMEVESDEEDEKQEKTDEPSTQLDQDTQVQDMDEGSDDEDESQKVPPPPETPMPPPLPPTPDQVIVRKDYDPKASKPLPPAPAPDEYLVSPITGEKIPASKMQEHMRIGLLDPRWLEQRDRSIREKQSDDEVYAPGLDIESSLKQLAERRTDIFGVEETAIGKKIGEEEIQKPEEKVTWDGHSGSMARTQQAAQANITLQEQIEAIHKAKGLVPEDDSKEKIGPSKPNEMPQPPPPSSASNPPPSAQPITSVPRPPTMPPPVRAAVVSAVPVMPRPPMTSVVRLPPGSVIATPMPPIIHTPRINVVPMPPSAPPIMSPRPPPMIVPTAFVPAPPVAPVPSPAPMPPVHPPPPMEDEPVSKKLKSEDSLIPEEEFLRRNKGPVTVKVQVPNMQDKTEWKLNGQVLVFTLPLSDQVSVIKVKIHEATGMPAGKQKLQYEGIFIKDSNSLAYYNMTSGSLIHLALKERGGRKK", "length": 790, "header": "tr|F1NU16-1|F1NU16_CHICK Isoform 1 of Splicing factor 3A subunit 1 OS=Gallus gallus OX=9031 GN=SF3A1 PE=1 SV=2 CANONICAL=F1NU16-1" }, "isoforms": [ { "isoform_ac": "A0A8V0WZP4-1", "url": "https://www.uniprot.org/uniprotkb/F1NU16/entry#A0A8V0WZP4-1", "sequence": { "sequence": "MPAGPVQAGPPAQPAPPAESKPPEEEPKEEAAPAKPVVGIIYPPPEVRNIVDKTASFVARNGPEFEARIRQNEINNPKFNFLNPNDPYHAYYRHKVSEFKEGKAQEPSAAIPKVMQQQQTAQQQLPQKVQAQVIQETVVPKEPPPEFEFIADPPSISAFDLDVVKLTAQFVARNGRQFLTQLMQKEQRNYQFDFLRPQHSLFNYFTKLVEQYTKILIPPKGLLIKLKKEAENPKEVLDQVYYRVEWAKFQERERKKEEEEKEKERVAYAQIDWHDFVVVETVDFQPNEQGNFPPPTTPEELGARILIQERYEKFGESEEVEMEVESDEEDEKQEKTDEPSTQLDQDTQVQDMDEGSDDEDESQKVPPPPETPMPPPLPPTPDQVIVRKDYDPKASKPLPPAPAPDEYLVSPITGEKIPASKMQEHMRIGLLDPRWLEQRDRSIREKQSDDEVYAPGLDIESSLKQLAERRTDIFGVEETAIGKKIGEEEIQKPEEKVTWDGHSGSMARTQQAAQANITLQEQIEAIHKAKGLVPEDDSKEKIGPSKPNEMPQPPPPSSASNPPPSAQPITSVPRPPTMPPPVRAAVVSAVPVMPRPPMTSVVRLPPGSVIATPMPPIIHTPRINVVPMPPSAPPIMSPRPPPMIVPTAFVPAPPVAPVPSPAPMPPVHPPPPMEDEPVSKKLKSEDSLIPEEEFLRRNKGPVTVKVQVPNMQDKTEWKLNGQVLVFTLPLSDQVSVIKVKIHEATGMPAGKQKLQYEVGISPSTLFVFQCFLTLKWTFLKKKLYH", "length": 785, "header": "tr|A0A8V0WZP4-1|A0A8V0WZP4_CHICK Computationally mapped isoform of Splicing factor 3A subunit 1 OS=Gallus gallus OX=9031 GN=SF3A1 PE=1 SV=1 CANONICAL=F1NU16-1" }, "locus": { "chromosome": "15", "start_pos": 10842662, "end_pos": 10830832, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010000431.1", "url": "https://www.ensembl.org/id/ENSGALT00010000431.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010000227.1", "url": "https://www.ensembl.org/id/ENSGALP00010000227.1" } ] } }, { "isoform_ac": "A0A8V0X2H7-1", "url": "https://www.uniprot.org/uniprotkb/F1NU16/entry#A0A8V0X2H7-1", "sequence": { "sequence": "MAFLKMSLLQPEEEPKEEAAPAKPVVGIIYPPPEVRNIVDKTASFVARNGPEFEARIRQNEINNPKFNFLNPNDPYHAYYRHKVSEFKEGKAQEPSAAIPKVMQQQQTAQQQLPQKVQAQVIQETVVPKEPPPEFEFIADPPSISAFDLDVVKLTAQFVARNGRQFLTQLMQKEQRNYQFDFLRPQHSLFNYFTKLVEQYTKILIPPKGLLIKLKKEAENPKEVLDQVYYRVEWAKFQERERKKEEEEKEKERVAYAQIDWHDFVVVETVDFQPNEQGNFPPPTTPEELGARILIQERYEKFGESEEVEMEVESDEEDEKQEKTDEPSTQLDQDTQVQDMDEGSDDEDESQKVPPPPETPMPPPLPPTPDQVIVRKDYDPKASKPLPPAPAPDEYLVSPITGEKIPASKMQEHMRIGLLDPRWLEQRDRSIREKQSDDEVYAPGLDIESSLKQLAERRTDIFGVEETAIGKKIGEEEIQKPEEKVTWDGHSGSMARTQQAAQANITLQEQIEAIHKAKGLVPEDDSKEKIGPSKPNEMPQPPPPSSASNPPPSAQPITSVPRPPTMPPPVRAAVVSAVPVMPRPPMTSVVRLPPGSVIATPMPPIIHTPRINVVPMPPSAPPIMSPRPPPMIVPTAFVPAPPVAPVPSPAPMPPVHPPPPMEDEPVSKKLKSEDSLIPEEEFLTQRGADVQVFQKKVPNMQDKTEWKLNGQVLVFTLPLSDQVSVIKVKIHEATGMPAGKQKLQYEGIFIKDSNSLAYYNMTSGSLIHLALKERGGRKK", "length": 779, "header": "tr|A0A8V0X2H7-1|A0A8V0X2H7_CHICK Computationally mapped isoform of Splicing factor 3A subunit 1 OS=Gallus gallus OX=9031 GN=SF3A1 PE=1 SV=1 CANONICAL=F1NU16-1" }, "locus": { "chromosome": "15", "start_pos": 10843574, "end_pos": 10832268, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010000428.1", "url": "https://www.ensembl.org/id/ENSGALT00010000428.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010000226.1", "url": "https://www.ensembl.org/id/ENSGALP00010000226.1" } ] } }, { "isoform_ac": "F1NU16-1", "url": "https://www.uniprot.org/uniprotkb/F1NU16/entry#F1NU16-1", "sequence": { "sequence": "MPAGPVQAGPPAQPAPPAESKPPEEEPKEEAAPAKPVVGIIYPPPEVRNIVDKTASFVARNGPEFEARIRQNEINNPKFNFLNPNDPYHAYYRHKVSEFKEGKAQEPSAAIPKVMQQQQTAQQQLPQKVQAQVIQETVVPKEPPPEFEFIADPPSISAFDLDVVKLTAQFVARNGRQFLTQLMQKEQRNYQFDFLRPQHSLFNYFTKLVEQYTKILIPPKGLLIKLKKEAENPKEVLDQVYYRVEWAKFQERERKKEEEEKEKERVAYAQIDWHDFVVVETVDFQPNEQGNFPPPTTPEELGARILIQERYEKFGESEEVEMEVESDEEDEKQEKTDEPSTQLDQDTQVQDMDEGSDDEDESQKVPPPPETPMPPPLPPTPDQVIVRKDYDPKASKPLPPAPAPDEYLVSPITGEKIPASKMQEHMRIGLLDPRWLEQRDRSIREKQSDDEVYAPGLDIESSLKQLAERRTDIFGVEETAIGKKIGEEEIQKPEEKVTWDGHSGSMARTQQAAQANITLQEQIEAIHKAKGLVPEDDSKEKIGPSKPNEMPQPPPPSSASNPPPSAQPITSVPRPPTMPPPVRAAVVSAVPVMPRPPMTSVVRLPPGSVIATPMPPIIHTPRINVVPMPPSAPPIMSPRPPPMIVPTAFVPAPPVAPVPSPAPMPPVHPPPPMEDEPVSKKLKSEDSLIPEEEFLRRNKGPVTVKVQVPNMQDKTEWKLNGQVLVFTLPLSDQVSVIKVKIHEATGMPAGKQKLQYEGIFIKDSNSLAYYNMTSGSLIHLALKERGGRKK", "length": 790, "header": "tr|F1NU16-1|F1NU16_CHICK Isoform 1 of Splicing factor 3A subunit 1 OS=Gallus gallus OX=9031 GN=SF3A1 PE=1 SV=2 CANONICAL=F1NU16-1" }, "locus": { "chromosome": "15", "start_pos": 10843574, "end_pos": 10830832, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010000434.1", "url": "https://www.ensembl.org/id/ENSGALT00010000434.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010000228.1", "url": "https://www.ensembl.org/id/ENSGALP00010000228.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 380, "start_aa": "Thr", "end_pos": 380, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr380", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:427717", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427717", "resource": "KEGG Pathway" }, { "id": "R-GGA-9770562", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9770562", "resource": "Reactome", "description": "mRNA Polyadenylation" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287ACP7-1", "protein_name": "Splicing factor 3a subunit 1", "gene_name": "SF3A1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MPAGPVQAVPPPPPAATEPKQPTEEEASSKEDSTPSKPVVGIIYPPPEVRNIVDKTASFVARNGPEFEARIRQNEINNPKFNFLNPNDPYHAYYRHKVSEFKEGKAQEPSAAIPKVMQQQQQATQQQLPQKVQAQVIQETIVPKEPPPEFEFIADPPSISAFDLDVVKLTAQFVARNGRQFLTQLMQKEQRNYQFDFLRPQHSLFNYFTKLVEQYTKILIPPKGLFTKLKKEAENPREVLDQVCYRVEWAKFQERERKKEEEEKEKERVAYAQIDWHDFVVVETVDFQPNEQGNFPPPTTPEELGARILIQERYEKFGESEEVEMEVESDDEDEKQDKAEEPPSQLDQDTQVQDMDEGSDDEEEGQKVPPPPETPMPPPLPPTPDQVIVRKDYDPKASKPLPPAPAPDEYLVSPITGEKIPASKMQEHMRIGLLDPRWLEQRDRSIREKQSDDEVYAPGLDIESSLKQLAERRTDIFGVEETAIGKKIGEEEIQKPEEKVTWDGHSGSMARTQQAAQANITLQEQIEAIHKAKGLVPEDDTKEKIGPSKPNEIPQQPPPPSSATNIPSSAPPITSVPRPPAMPPPVRTTVVSAVPVMPRPPMASVVRLPPGSVIAPMPPIIHAPRINVVPMPPSAPPIMAPRPPPMIVPTAFVPAPPVAPVPAPAPMPPVHPPPPMEDEPASKKLKTEDSLMPEEEFLRRNKVCDPVVLPMAWPGVPRLGLG", "length": 722 }, "evidence": [ { "id": "F1NU16", "url": "https://omabrowser.org/oma/group/F1NU16/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A2VDN6-1", "protein_name": "Splicing factor 3A subunit 1", "gene_name": "SF3A1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MPAGPVQAVPPPPPAATEPKQPTEEEASSKEDSTPSKPVVGIIYPPPEVRNIVDKTASFVARNGPEFEARIRQNEINNPKFNFLNPNDPYHAYYRHKVSEFKEGKAQEPSAAIPKVMQQQQQASQQQLPQKVQAQVIQETIVPKEPPPEFEFIADPPSISAFDLDVVKLTAQFVARNGRQFLTQLMQKEQRNYQFDFLRPQHSLFNYFTKLVEQYTKILIPPKGLFTKLKKEAENPREVLDQVCYRVEWAKFQERERKKEEEEKEKERVAYAQIDWHDFVVVETVDFQPNEQGNFPPPTTPEELGARILIQERYEKFGESEEVEMEVESDEEDEKQEKAEEPPSQLDQDTQVQDMDEGSDDEEEGQKVPPPPETPMPPPLPPTPDQVIVRKDYDPKASKPLPPAPAPDEYLVSPITGEKIPASKMQEHMRIGLLDPRWLEQRDRSIREKQSDDEVYAPGLDIESSLKQLAERRTDIFGVEETAIGKKIGEEEIQKPEEKVTWDGHSGSMARTQQAAQANITLQEQIEAIHKAKGLVPEDDTKEKIGPSKPNEIPQQPPPPSSATNIPSSAPPITSVPRPPAMPPPVRTTVVSAVPVMPRPPMASVVRLPPGSVIAPMPPIIHAPRINVVPMPPSAPPIMAPRPPPMIVPTAFVPAPPVAPVPAPAPMPPVHPPPPMEDEPASKKLKTEDSLMPEEEFLRRNKGPVSIKVQVPNMQDKTEWKLNGQVLVFTLPLTDQVSVIKVKIHEATGMPAGKQKLQYEGIFIKDSNSLAYYNMANGAVIHLALKERGGRKK", "length": 793 }, "evidence": [ { "id": "F1NU16", "url": "https://omabrowser.org/oma/group/F1NU16/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "D3ZQM0-1", "protein_name": "Splicing factor 3A subunit 1", "gene_name": "Sf3a1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQAGPVQAVPPPPPVVTEPKQPNEEEASSKEDSTPSKPVVGIIYPPPEVRNIVDKTASFVARNGPEFEARIRQNEINNPKFNFLNPNDPYHAYYRHKVSEFKEGKAQEPSAAIPKVMQQQQQATQQQLPQKVQAQVIQETIVPKEPPPEFEFIADPPSISAFDLDVVKLTAQFVARNGRQFLTQLMQKEQRNYQFDFLRPQHSLFNYFTKLVEQYTKILIPPKGLFAKLKKEAENPREVLDQVCYRVEWAKFQERERKKEEEEKEKERVAYAQIDWHDFVVVETVDFQPNEQGNFPPPTTPEELGARILIQERYEKFGESEEVEMEVESDEEDQEKTEETPSQLDQDTQVQDMDEGSDDEEEGQKVPPPPETPMPPPLPPTPDQVIVRKDYDPKASKPLPPAPAPDEYLVSPITGEKIPASKMQEHMRIGLLDPRWLEQRDRSIREKQSDDEVYAPGLDIESSLKQLAERRTDIFGVEETAIGKKIGEEEIQKPEEKVTWDGHSGSMARTQQAAQANITLQEQIEAIHKAKGLVPEDDTKEKIGPSKPNEIPQQPPPPSSATNIPSSAPPITSVPRPPAMPPPVRTTVVSAVPVMPRPPMASVVRLPPGSVIAPMPPIIHAPRINVVPMPPAAPPIMAPRPPPMIVPTAFVPAPPVAPVPAPAPMPPVHPPPPMEDEPPSKKLKTEDSLMPEEEFLRRNKGPVSIKVQVPNMQDKTEWKLNGQGLVFTLPLTDQVSVIKVKIHEATGMPAGKQKLQYEGIFIKDSNSLAYYNMASGAVIHLALKERGGRKK", "length": 791 }, "evidence": [ { "id": "F1NU16", "url": "https://omabrowser.org/oma/group/F1NU16/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3I142-1", "protein_name": "Splicing factor 3A subunit 1", "gene_name": "Sf3a1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MPAGPVQAVPPPPPVATEPKQPVEEEASSKEESTPSKPVVGIIYPPPEVRNIVDKTASFVARNGPEFEARIRQNEINNPKFNFLNPNDPYHAYYRHKVSEFKEGKAQEPSAAIPKVMQQQQQATQQQLPQKVQAQVIQETIVPKEPPPEFEFIADPPSISAFDLDVVKLTAQFVARNGRQFLTQLMQKEQRNYQFDFLRPQHSLFNYFTKLVEQYTKILIPPKGLFAKLKKEAENPREVLDQVCYRVEWAKFQERERKKEEEEKEKERVAYAQIDWHDFVVVETVDFQPNEQGNFPPPTTPEELGARILIQERYEKFGESEEVEMEVESDEEDEKQEKAEEAPSQLDQDTQVQDMDEGSDDDEEGQKVPPPPETPMPPPLPPTPDQVIVRKDYDPKASKPLPPAPAPDEYLVSPITGEKIPASKMQEHMRIGLLDPRWLEQRDRSIREKQSDDEVYAPGLDIESSLKQLAERRTDIFGVEETAIGKKIGEEEIQKPEEKVTWDGHSGSMARTQQAAQANITLQEQIEAIHKAKGLVPEDDTKEKIGPSKPNEIPQQPPPPSSATNIPSSAPPITSVPRPPAMPPPVRTTVVSAVPVMPRPPMASVVRLPPGSVIAPMPPIIHAPRINVVPMPPAAPPIMAPRPPPMIVPTAFVPAPPVAPVPAPAPMPPVHPPPPMEDEPPSKKLKTEDSLMPEEEFLRRNKGPVSIKVQVPNMQDKTEWKLNGQGLVFTLPLTDQVSVIKVKIHEATGMPAGKQKLQYEGIFIKDSNSLAYYNMASGAVIHLALKERGGRKK", "length": 793 }, "evidence": [ { "id": "F1NU16", "url": "https://omabrowser.org/oma/group/F1NU16/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q15459-1", "protein_name": "Splicing factor 3A subunit 1", "gene_name": "SF3A1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPAGPVQAVPPPPPVPTEPKQPTEEEASSKEDSAPSKPVVGIIYPPPEVRNIVDKTASFVARNGPEFEARIRQNEINNPKFNFLNPNDPYHAYYRHKVSEFKEGKAQEPSAAIPKVMQQQQQTTQQQLPQKVQAQVIQETIVPKEPPPEFEFIADPPSISAFDLDVVKLTAQFVARNGRQFLTQLMQKEQRNYQFDFLRPQHSLFNYFTKLVEQYTKILIPPKGLFSKLKKEAENPREVLDQVCYRVEWAKFQERERKKEEEEKEKERVAYAQIDWHDFVVVETVDFQPNEQGNFPPPTTPEELGARILIQERYEKFGESEEVEMEVESDEEDDKQEKAEEPPSQLDQDTQVQDMDEGSDDEEEGQKVPPPPETPMPPPLPPTPDQVIVRKDYDPKASKPLPPAPAPDEYLVSPITGEKIPASKMQEHMRIGLLDPRWLEQRDRSIREKQSDDEVYAPGLDIESSLKQLAERRTDIFGVEETAIGKKIGEEEIQKPEEKVTWDGHSGSMARTQQAAQANITLQEQIEAIHKAKGLVPEDDTKEKIGPSKPNEIPQQPPPPSSATNIPSSAPPITSVPRPPTMPPPVRTTVVSAVPVMPRPPMASVVRLPPGSVIAPMPPIIHAPRINVVPMPPSAPPIMAPRPPPMIVPTAFVPAPPVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMPEEEFLRRNKGPVSIKVQVPNMQDKTEWKLNGQVLVFTLPLTDQVSVIKVKIHEATGMPAGKQKLQYEGIFIKDSNSLAYYNMANGAVIHLALKERGGRKK", "length": 793 }, "evidence": [ { "id": "F1NU16", "url": "https://omabrowser.org/oma/group/F1NU16/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q86A14-1", "protein_name": "Probable splicing factor 3A subunit 1", "gene_name": "sf3a1", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MANEIITPTEGELKTIIDKTAAYAAKLGESFENKVKQREGHNAKFNFMKEGDQYYPYYRNKIVENKAKIQADAAAAAAAANPKTPSTTTTTTTTTTATTPLPTATATTTSPTPTTSSTIVPVPQTNSTQQLQQQQQQQQQTTPVFEKPQPPPPPPPKKEPTQPDPLLYILDVPDFMTPLELDTIRLTAQFIAKNGDSFFMELASREVKNSQFDFLKPTNHLYEWFRALVESYAQIIYPPQGIKEQLKSNYFSNKQTILERAMNRCEYNQLKEIEEQKKEEREDEEKTIIASIDWHDFVIVDTIEFNEDDLDDLPQPRTFDQLIAGDTPFGGSDFDNDGHGSNGKGGQDMEMEMDMEMEMDDEDNNNNEDEIEESSLSSTNTTGNLPPKDQSKLKIVKDYQKSNSSVKSNAPTKLTQLCQFCKQEIPLDEMQEHMRIELIQKQQRDSRLGGGGSSNNNNNLTNTLTQDDDIARNLQSFASKRVDIFGETESSKKQDEQPTQAPKVIWDGHSGSIPRVQAAQQAAQLAAQQAAQQKAAAIAAQQASQQQASQQQQQQLQPPQPIGIHHHPQRHLPPGMMPPGMMPPGMMPPGMMPPGMVPPPPFGMIPPGMVPPPPPGLMIPTAPPGLMIPPTQQQQLPPQTNTSPSSSSSIKVEEPQSKKLKIDDVLIPESVWLQNNPNPVNLTVEMADKSNIYQITLQPTDSISLLKEKIKELNGMPTNKQKLQAPGLSILKDTCSIAFYNLKSLAIVTCGQKKKGGKKK", "length": 760 }, "evidence": [ { "id": "F1NU16", "url": "https://omabrowser.org/oma/group/F1NU16/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q8K4Z5-1", "protein_name": "Splicing factor 3A subunit 1", "gene_name": "Sf3a1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MQAGPVQAVPPPPPVATESKQPIEEEASSKEDPTPSKPVVGIIYPPPEVRNIVDKTASFVARNGPEFEARIRQNEINNPKFNFLNPNDPYHAYYRHKVSEFKEGKAQEPSAAIPKVMQQQQQATQQQLPQKVQAQVIQETIVPKEPPPEFEFIADPPSISAFDLDVVKLTAQFVARNGRQFLTQLMQKEQRNYQFDFLRPQHSLFNYFTKLVEQYTKILIPPKGLFSKLKKEAENPREVLDQVCYRVEWAKFQERERKKEEEEKEKERVAYAQIDWHDFVVVETVDFQPNEQGNFPPPTTPEELGARILIQERYEKFGESEEVEMEVESDEEDQEKAEETPSQLDQDTQVQDMDEGSDDEEEGQKVPPPPETPMPPPLPPTPDQVIVRKDYDPKASKPLPPAPAPDEYLVSPITGEKIPASKMQEHMRIGLLDPRWLEQRDRSIREKQSDDEVYAPGLDIESSLKQLAERRTDIFGVEETAIGKKIGEEEIQKPEEKVTWDGHSGSMARTQQAAQANITLQEQIEAIHKAKGLVPEDDTKEKIGPSKPNEIPQQPPPPSSATNIPSSAPPITSVPRPPAMPPPVRTTVVSAVPVMPRPPMASVVRLPPGSVIAPMPPIIHAPRINVVPMPPAAPPIMAPRPPPMIVPTAFVPAPPVAPVPAPAPMPPVHPPPPMEDEPPSKKLKTEDSLMPEEEFLRRNKGPVSIKVQVPNMQDKTEWKLNGQGLVFTLPLTDQVSVIKVKIHEATGMPAGKQKLQYEGIFIKDSNSLAYYNMASGAVIHLALKERGGRKK", "length": 791 }, "evidence": [ { "id": "F1NU16", "url": "https://omabrowser.org/oma/group/F1NU16/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8RXF1-1", "protein_name": "Probable splicing factor 3A subunit 1", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MFSSMQILPLEAPPTDGKLGPLPPSQLTDQEVEERELQAEQNNSNLAPPAAVATHTRTIGIIHPPPDIRTIVEKTAQFVSKNGLEFEKRIIVSNEKNAKFNFLKSSDPYHAFYQHKLTEYRAQNKDGAQGTDDSDGTTDPQLDTGAADESEAGDTQPDLQAQFRIPSKPLEAPEPEKYTVRLPEGITGEELDIIKLTAQFVARNGKSFLTGLSNRENNNPQFHFMKPTHSMFTFFTSLVDAYSEVLMPPKDLKEKLRKSAADLTTVLERCLHRLEWDRSQEQQKKKEEDEKELERVQMAMIDWHDFVVVESIDFADEEDEELPPPMTLDEVIRRSKASAMEEDEIVEPGKEVEMEMDEEEVKLVAEGMRAANLEENVKIENVHDEEAPMRIVKNWKRPEDRIPTERDPTKVVISPITGELIPINEMSEHMRISLIDPKFKEQKDRMFAKIRETTLAQDDEIAKNIVGLARLRPDIFGTTEEEVSNAVKAEIEKKKDEQPKQVIWDGHTGSIGRTANQALSQNANGEEQGDGVYGDPNSFPGPAALPPPRPGVPIVRPLPPPPNLALNLPRPPPSAQYPGAPRPLGVPMMQPMHQQHQLTMPGPPGHPQMMMNRPPQMQPGMHVPPPPGSQFAHHMQIPRPYGQLPPSAMGMMQPPPMPGMAPPPPPEEAPPPLPEEPEAKRQKFDESALVPEDQFLAQHPGPATIRVSKPNENDGQFMEITVQSLSENVGSLKEKIAGEIQIPANKQKLSGKAGFLKDNMSLAHYNVGAGEILTLSLRERGGRKR", "length": 785 }, "evidence": [ { "id": "F1NU16", "url": "https://omabrowser.org/oma/group/F1NU16/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9VEP9-1", "protein_name": "Splicing factor 3A subunit 1", "gene_name": "Sf3a1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MATLDAEANEEQFGNDQPKSMSGPIIGIIYPPPEVRNIVDKTASFVARNGPEFEARIRQNELGNPKFNFLNGGDPYHAYYRHKVNEFREGNDAGITALASMKQLAVTSAAQQRQQELLKQVVEQQFVPKEPPPEFEFIADPPSISALDLDIVKLTAQFVARNGRQFLTNLMSREQRNFQFDFLRPQHSLFQYFTKLLEQYTKVLIPPKDLLGKLRSESAPGRSSMNQVLEQVKYRANWQRHQEAQRRREEEKIERERVAYAQIDWHDFVVVETVDYQPFESGNFPPPTNPDEVGARVLMEERLMDEEGDTEMQIESDDEGDSQANNLLDSGLKLSQMENRVGIQMKNVSSYGQPTGPKRDNTQVQDMDEASSDEDTPTTKLQPSVAPMLPPTHDKVVVKKYDPKATQPKQAPMPTDEYLISPITGEKIPASKVSEHMRIGLLDPRWVEQRDKHTVEKINQDNVFAAGTAIEASLKQLAERRTDIFGVGDEETVIGKKLGEEETKKDDRVTWDGHTSSVEAATRAARANITLEEQIHQIHKVKGLLPDEEKEKIGPKPVGNKATLSAPPQPSTKSQHSHSSQSQHHQGGGGGHHGHHNPHHHHPPHQQAPPHQSHHHHPPQQPQPVMQLMQLRPTMMQPPFGAGGGGYMNMQPGGIPQQIAPAPPVDIMEEEPPSKKIRSEDNLIPEADFIATHKSPVTIQVLVPNSDKSEWKLNGQMIAVTMALSEPIANLKTKLQDETGMPPAKQKIFYEGMFFKDSNTMAFYNLVNGTTVHLQVKERGGRKK", "length": 784 }, "evidence": [ { "id": "F1NU16", "url": "https://omabrowser.org/oma/group/F1NU16/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "F1NU16", "url": "https://www.uniprot.org/uniprotkb/F1NU16" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "nuclear speck", "id": "GO:0016607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016607", "evidence": [ { "database": "UniProtKB", "id": "F1NU16", "url": "https://www.uniprot.org/uniprotkb/F1NU16" } ], "pmid": "" }, { "name": "spliceosomal complex", "id": "GO:0005681", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005681", "evidence": [ { "database": "UniProtKB", "id": "F1NU16", "url": "https://www.uniprot.org/uniprotkb/F1NU16" } ], "pmid": "" }, { "name": "U2 snRNP", "id": "GO:0005686", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005686", "evidence": [ { "database": "UniProtKB", "id": "F1NU16", "url": "https://www.uniprot.org/uniprotkb/F1NU16" } ], "pmid": "" }, { "name": "catalytic step 2 spliceosome", "id": "GO:0071013", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071013", "evidence": [ { "database": "UniProtKB", "id": "F1NU16", "url": "https://www.uniprot.org/uniprotkb/F1NU16" } ], "pmid": "" }, { "name": "U2-type prespliceosome", "id": "GO:0071004", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071004", "evidence": [ { "database": "UniProtKB", "id": "F1NU16", "url": "https://www.uniprot.org/uniprotkb/F1NU16" } ], "pmid": "" }, { "name": "U2-type precatalytic spliceosome", "id": "GO:0071005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071005", "evidence": [ { "database": "UniProtKB", "id": "F1NU16", "url": "https://www.uniprot.org/uniprotkb/F1NU16" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "mRNA cis splicing, via spliceosome", "id": "GO:0045292", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045292", "evidence": [ { "database": "UniProtKB", "id": "F1NU16", "url": "https://www.uniprot.org/uniprotkb/F1NU16" } ], "pmid": "" }, { "name": "U2-type prespliceosome assembly", "id": "GO:1903241", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903241", "evidence": [ { "database": "UniProtKB", "id": "F1NU16", "url": "https://www.uniprot.org/uniprotkb/F1NU16" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 516, "end_pos": 518, "annotation": "n_glycosylation_sequon" }, { "start_pos": 771, "end_pos": 773, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1NU16-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 790, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1NU16-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1NU16" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 380 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 516, "end_pos": 518 }, { "start_pos": 771, "end_pos": 773 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1NJG5-1", "uniprot_ac": "F1NJG5", "uniprot_id": "F1NJG5_CHICK", "mass": { "chemical_mass": 29157.0, "monoisotopic_mass": 29157.0 }, "refseq": { "ac": "NP_001292153", "name": "homeobox protein Hox-A9", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001292153" }, "gene_names": [ { "name": "HOXA9", "type": "recommended", "evidence": [ { "id": "F1NJG5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NJG5" } ] }, { "name": "HOXA-9", "type": "synonym", "evidence": [ { "id": "NP_001292153", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001292153" } ] }, { "name": "HOXA9", "type": "synonym", "evidence": [ { "id": "NP_001292153", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001292153" } ] } ], "protein_names": [ { "name": "Homeobox protein", "type": "recommended", "evidence": [ { "id": "F1NJG5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NJG5/entry#names_and_taxonomy" } ] }, { "name": "homeobox protein Hox-A9", "type": "synonym", "evidence": [ { "id": "NP_001292153", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001292153" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: CR391427.1, BU253718.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000037.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001292153", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001292153" } ] }, { "annotation": "Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.", "evidence": [ { "database": "UniProtKB", "id": "F1NJG5", "url": "https://www.uniprot.org/uniprotkb/F1NJG5#function" }, { "database": "UniProtKB", "id": "PIRNR037109", "url": "https://www.uniprot.org/uniprotkb/PIRNR037109#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NJG5", "url": "https://www.uniprot.org/uniprotkb/F1NJG5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "HOXA9", "url": "https://www.uniprot.org/uniprotkb/F1NJG5", "locus": { "chromosome": "2", "start_pos": 32546009, "end_pos": 32563954, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010001840", "url": "https://www.ensembl.org/id/ENSGALG00010001840" } ] } } ], "crossref": [ { "id": "F1NJG5", "url": "https://alphafold.ebi.ac.uk/entry/F1NJG5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000028983", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000028983", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00086", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00086", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "396096", "url": "https://www.ncbi.nlm.nih.gov/gene/396096", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001356", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001356", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006711", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006711", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009057", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009057", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017112", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017112", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017970", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017970", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020479", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020479", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:396096", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:396096", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "GEHPEFT", "url": "https://omabrowser.org/oma/group/GEHPEFT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0X784", "url": "https://www.orthodb.org/?gene=A0A8V0X784", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NJG5", "url": "https://www.orthodb.org/?gene=F1NJG5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45970", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45970", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45970:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45970:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00046", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00046", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF04617", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04617", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001292153", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001292153", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0X784", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X784", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0X784-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X784-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NJG5", "url": "https://www.uniprot.org/uniprotkb/F1NJG5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NJG5-1", "url": "https://www.uniprot.org/uniprotkb/F1NJG5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSAPGTLSNYYVDSFLVPEGDELAAPRYAPAPLGPPPRPALAEHPELTPCSFQPKAPVFGPPWSPAHPAGASGVPAVYHPYAHHQAPVAPPDGRYMRSWLEPVPGSLSFPGLPTSRHYGIKPEPLAARRGDCTTFDTHTLSLSDYACGSPPVDRDKQSHEGAFSENNGESEANGEKPHIDPNNPAANWLHARSTRKKRCPYTKHQTLELEKEFLFNMYLTRDRRYEVARLLNLTERQVKIWFQNRRMKMKKINKDRAKDE", "length": 260, "header": "tr|F1NJG5-1|F1NJG5_CHICK Isoform 1 of Homeobox protein OS=Gallus gallus OX=9031 GN=HOXA9 PE=3 SV=2 CANONICAL=F1NJG5-1" }, "isoforms": [ { "isoform_ac": "A0A8V0X784-1", "url": "https://www.uniprot.org/uniprotkb/F1NJG5/entry#A0A8V0X784-1", "sequence": { "sequence": "MSAPGTLSNYYVDSFLVPEGDELAAPRYAPAPLGPPPRPALAEHPELTPCSFQPKAPVFGPPWSPAHPAGASGVPAVYHPYAHHQAPVAPPDGRYMRSWLEPVPGSLSFPGLPTSRHYGIKPEPLAARRGDCTTFDTHTLSLSDYACGSPPVDRDKQSHEGAFSENNGESEANGEKPHIDPSKWGCGAARLGPGRRRGAGLRAARAPGTESRAAPRGLCRDPGRLRLCGPRGEQNPSPRLRLKIK", "length": 245, "header": "tr|A0A8V0X784-1|A0A8V0X784_CHICK Computationally mapped isoform of Homeobox A9 OS=Gallus gallus OX=9031 GN=HOXA9 PE=4 SV=1 CANONICAL=F1NJG5-1" }, "locus": { "chromosome": "2", "start_pos": 32547131, "end_pos": 32546397, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010004188.1", "url": "https://www.ensembl.org/id/ENSGALT00010004188.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010002485.1", "url": "https://www.ensembl.org/id/ENSGALP00010002485.1" } ] } }, { "isoform_ac": "F1NJG5-1", "url": "https://www.uniprot.org/uniprotkb/F1NJG5/entry#F1NJG5-1", "sequence": { "sequence": "MSAPGTLSNYYVDSFLVPEGDELAAPRYAPAPLGPPPRPALAEHPELTPCSFQPKAPVFGPPWSPAHPAGASGVPAVYHPYAHHQAPVAPPDGRYMRSWLEPVPGSLSFPGLPTSRHYGIKPEPLAARRGDCTTFDTHTLSLSDYACGSPPVDRDKQSHEGAFSENNGESEANGEKPHIDPNNPAANWLHARSTRKKRCPYTKHQTLELEKEFLFNMYLTRDRRYEVARLLNLTERQVKIWFQNRRMKMKKINKDRAKDE", "length": 260, "header": "tr|F1NJG5-1|F1NJG5_CHICK Isoform 1 of Homeobox protein OS=Gallus gallus OX=9031 GN=HOXA9 PE=3 SV=2 CANONICAL=F1NJG5-1" }, "locus": { "chromosome": "2", "start_pos": 32549112, "end_pos": 32547372, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010004190.1", "url": "https://www.ensembl.org/id/ENSGALT00010004190.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010002487.1", "url": "https://www.ensembl.org/id/ENSGALP00010002487.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:396096", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:396096", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZSU5-1", "protein_name": "Homeobox A9", "gene_name": "Hoxa9", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MATTGALGNYYVDSFLLGADAADELGAGRYAPGALGQPQRQAAALAEHPDFSPCSFQSKAAVFGASWNPVHAAGANAVPAAVYHHHHHPYVHPQAPVAAAAPDGRYMRSWLEPTPGALSFAGLPSSRPYGIKPEPLSARRGDCPTLDTHTLSLTDYACGSPPVDREKQPSEGAFSENNAENESGGDKPPIDPSKCLLPANRPLPPRRPPGSTSASAFSRACLRSRWVPLNLGPENQKLVFGTPLIGAPSPENRVDQAGPARGKGGGYCSTRGRGGRASGAETRRPSPKLPRPRTDRLWAVLRKQRREVFCAARLCTNCGSDVSRAI", "length": 326 }, "evidence": [ { "id": "F1NJG5", "url": "https://omabrowser.org/oma/group/F1NJG5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1SHT5-1", "protein_name": "Homeobox protein", "gene_name": "HOXA9", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MATTGALGNYYVDSFLLGADAADELSAGRYAPGALGQPPRQAAALAEHPDFSPCSFQSKAAVFGASWNPVHAAGANAVPAAVYHHHHHHPYVHPQAPVAAAAPDGRYMRSWLEPTPGALSFAGLPSSRPYGIKPEPLSARRGDCPTLDTHTLSLTDYACGSPPVDREKQPSEGAFSENNAENESGGDKPPIDPSNPAANWLHARSTRKKRCPYTKHQTLELEKEFLFNMYLTRDRRYEVARLLNLTERQVKIWFQNRRMKMKKINKDRAKDE", "length": 272 }, "evidence": [ { "id": "F1NJG5", "url": "https://omabrowser.org/oma/group/F1NJG5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3HD80-1", "protein_name": "Homeobox protein", "gene_name": "Hoxa9", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MATTGALGNYYVDSFLLGTDAADELGAGRYAPGALGQPPRQAAALAEHPDFSPCSFQSKTAVFGASWNPVHAAGANAVPAAVYHHHHHPYVHPQAPVAAAAPDGRYMRSWLEPTPGALSFAGLPSSRPYGIKPEPLSARRGDCPTLDTHTLSLTDYACGSPPVDREKQPSEGAFSENNAENESGGDKPPIDPNNPAANWLHARSTRKKRCPYTKHQTLELEKEFLFNMYLTRDRRYEVARLLNLTERQVKIWFQNRRMKMKKINKDRAKDE", "length": 271 }, "evidence": [ { "id": "F1NJG5", "url": "https://omabrowser.org/oma/group/F1NJG5/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P09631-1", "protein_name": "Homeobox protein Hox-A9", "gene_name": "Hoxa9", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MATTGALGNYYVDSFLLGADAADELGAGRYAPGTLGQPPRQAAALAEHPDFSPCSFQSKAAVFGASWNPVHAAGANAVPAAVYHHHHHPYVHPQAPVAAAAPDGRYMRSWLEPTPGALSFAGLPSSRPYGIKPEPLSARRGDCPTLDTHTLSLTDYACGSPPVDREKQPSEGAFSENNAENESGGDKPPIDPNNPAANWLHARSTRKKRCPYTKHQTLELEKEFLFNMYLTRDRRYEVARLLNLTERQVKIWFQNRRMKMKKINKDRAKDE", "length": 271 }, "evidence": [ { "id": "F1NJG5", "url": "https://omabrowser.org/oma/group/F1NJG5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P31269-1", "protein_name": "Homeobox protein Hox-A9", "gene_name": "HOXA9", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MATTGALGNYYVDSFLLGADAADELSVGRYAPGTLGQPPRQAATLAEHPDFSPCSFQSKATVFGASWNPVHAAGANAVPAAVYHHHHHHPYVHPQAPVAAAAPDGRYMRSWLEPTPGALSFAGLPSSRPYGIKPEPLSARRGDCPTLDTHTLSLTDYACGSPPVDREKQPSEGAFSENNAENESGGDKPPIDPNNPAANWLHARSTRKKRCPYTKHQTLELEKEFLFNMYLTRDRRYEVARLLNLTERQVKIWFQNRRMKMKKINKDRAKDE", "length": 272 }, "evidence": [ { "id": "F1NJG5", "url": "https://omabrowser.org/oma/group/F1NJG5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1NJG5", "url": "https://www.uniprot.org/uniprotkb/F1NJG5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "F1NJG5", "url": "https://www.uniprot.org/uniprotkb/F1NJG5" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "F1NJG5", "url": "https://www.uniprot.org/uniprotkb/F1NJG5" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "F1NJG5", "url": "https://www.uniprot.org/uniprotkb/F1NJG5" } ], "pmid": "" }, { "name": "anterior/posterior pattern specification", "id": "GO:0009952", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009952", "evidence": [ { "database": "UniProtKB", "id": "F1NJG5", "url": "https://www.uniprot.org/uniprotkb/F1NJG5" } ], "pmid": "" }, { "name": "proximal/distal pattern formation", "id": "GO:0009954", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009954", "evidence": [ { "database": "UniProtKB", "id": "F1NJG5", "url": "https://www.uniprot.org/uniprotkb/F1NJG5" } ], "pmid": "" }, { "name": "embryonic skeletal system morphogenesis", "id": "GO:0048704", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048704", "evidence": [ { "database": "UniProtKB", "id": "F1NJG5", "url": "https://www.uniprot.org/uniprotkb/F1NJG5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "F1NJG5", "url": "https://www.uniprot.org/uniprotkb/F1NJG5" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "F1NJG5", "url": "https://www.uniprot.org/uniprotkb/F1NJG5" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "F1NJG5", "url": "https://www.uniprot.org/uniprotkb/F1NJG5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 232, "end_pos": 234, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1NJG5-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 260, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1NJG5-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1NJG5" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1NJG5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NJG5" }, { "id": "PRU00108", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00108" } ], "ann_type": "Nucleotide_Binding_Annotation", "uniprotkb_annotation": "Homeobox", "eco_id": "ECO_0000256", "start_pos": 194, "end_pos": 253, "start_aa": "Thr", "end_aa": "Asn", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 232, "end_pos": 234 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": 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"o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1NSL4-1", "uniprot_ac": "F1NSL4", "uniprot_id": "F1NSL4_CHICK", "mass": { "chemical_mass": 66097.0, "monoisotopic_mass": 66097.0 }, "refseq": {}, "gene_names": [ { "name": "KLHL7", "type": "recommended", "evidence": [ { "id": "F1NSL4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NSL4" } ] } ], "protein_names": [ { "name": "Kelch-like protein 7", "type": "recommended", "evidence": [ { "id": "F1NSL4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NSL4/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex. The BCR(KLHL7) complex acts by mediating ubiquitination and subsequent degradation of substrate proteins. Probably mediates 'Lys-48'-linked ubiquitination.", "evidence": [ { "database": "UniProtKB", "id": "F1NSL4", "url": "https://www.uniprot.org/uniprotkb/F1NSL4#function" }, { "database": "UniProtKB", "id": "ARBA00059954", "url": "https://www.uniprot.org/uniprotkb/ARBA00059954#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NSL4", "url": "https://www.uniprot.org/uniprotkb/F1NSL4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "KLHL7", "url": "https://www.uniprot.org/uniprotkb/F1NSL4", "locus": { "chromosome": "2", "start_pos": 30885597, "end_pos": 30861197, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010001397", "url": "https://www.ensembl.org/id/ENSGALG00010001397" } ] } } ], "crossref": [ { "id": "F1NSL4", "url": "https://alphafold.ebi.ac.uk/entry/F1NSL4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000010938", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000010938", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd18237", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18237", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd18447", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18447", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "420612", "url": "https://www.ncbi.nlm.nih.gov/gene/420612", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000210", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000210", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006652", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006652", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011333", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011333", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011705", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011705", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015915", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015915", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017096", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017096", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR030599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR030599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047060", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047060", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:420612", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420612", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WRAASPM", "url": "https://omabrowser.org/oma/group/WRAASPM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XAZ6", "url": "https://www.orthodb.org/?gene=A0A8V0XAZ6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NSL4", "url": "https://www.orthodb.org/?gene=F1NSL4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24412", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24412", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24412:SF435", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24412:SF435", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00651", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00651", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07707", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07707", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24681", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24681", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001012875", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012875", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0XAZ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XAZ6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XAZ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XAZ6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NSL4", "url": "https://www.uniprot.org/uniprotkb/F1NSL4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NSL4-1", "url": "https://www.uniprot.org/uniprotkb/F1NSL4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAPGSEKSSKKKTEKKLAAREEAKLLAGFMGVMNSMRKQRTLCDVILMVQERRIPAHRVVLASASHFFNLMFTTNMLESKSFEVELKDAEPDIIEQLVEFAYTARISVNSNNVQSLLDAANQYQIEPVKKMCVDFLKEQVDASNCLGISVLAECLDCPELKATADDFIHQHFTEVYKTDEFLQLDVKRVTHLLNQDTLTVRAEDQVYDAAVRWLKYDEPNRQPYMVDILAKVRFPLISKNFLSKTVQAEPLIQDNPECLKMVISGMRYHLLSPEDREELVEGTRPRRKKHDYRIALFGGSQPQSCRYFNPKDYSWTDIRCPFEKRRDAACVFWDNVVYILGGSQLFPIKRMDCYNVVKDSWYSKLGPPTPRDSLAACAAEGKIYTSGGSEVGNSALYLFECYDTRTESWHTKPSMLTQRCSHGMVEANGLIYVCGGSLGNNVSGRVLNSCEVYDPATETWTELCPMIEARKNHGLVFVKDKIFAVGGQNGLGGLDNVEYYDIKMNEWKMVSPMPWKGVTVKCAAVGSIVYVLAGFQGVGRLGHILEYNTETDKWIANSKVRAFPVTSCLICVVDTCGANEETLET", "length": 586, "header": "tr|F1NSL4-1|F1NSL4_CHICK Isoform 1 of Kelch-like protein 7 OS=Gallus gallus OX=9031 GN=KLHL7 PE=4 SV=1 CANONICAL=F1NSL4-1" }, "isoforms": [ { "isoform_ac": "A0A8V0XAZ6-1", "url": "https://www.uniprot.org/uniprotkb/F1NSL4/entry#A0A8V0XAZ6-1", "sequence": { "sequence": "MVQERRIPAHRVVLASASHFFNLMFTTNMLESKSFEVELKDAEPDIIEQLVEFAYTARISVNSNNVQSLLDAANQYQIEPVKKMCVDFLKEQVDASNCLGISVLAECLDCPELKATADDFIHQHFTEVYKTDEFLQLDVKRVTHLLNQDTLTVRAEDQVYDAAVRWLKYDEPNRQPYMVDILAKVRFPLISKNFLSKTVQAEPLIQDNPECLKMVISGMRYHLLSPEDREELVEGTRPRRKKHDYRIALFGGSQPQSCRYFNPKDYSWTDIRCPFEKRRDAACVFWDNVVYILGGSQLFPIKRMDCYNVVKDSWYSKLGPPTPRDSLAACAAEGKIYTSGGSEVGNSALYLFECYDTRTESWHTKPSMLTQRCSHGMVEANGLIYVCGGSLGNNVSGRVLNSCEVYDPATETWTELCPMIEARKNHGLVFVKDKIFAVGGQNGLGGLDNVEYYDIKMNEWKMVSPMPWKGVTVKCAAVGSIVYVLAGFQGVGRLGHILEYNTETDKWIANSKVRAFPVTSCLICVVDTCGANEETLET", "length": 538, "header": "tr|A0A8V0XAZ6-1|A0A8V0XAZ6_CHICK Computationally mapped isoform of Kelch like family member 7 OS=Gallus gallus OX=9031 GN=KLHL7 PE=4 SV=1 CANONICAL=F1NSL4-1" }, "locus": { "chromosome": "2", "start_pos": 30884659, "end_pos": 30864925, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010003220.1", "url": "https://www.ensembl.org/id/ENSGALT00010003220.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010001677.1", "url": "https://www.ensembl.org/id/ENSGALP00010001677.1" } ] } }, { "isoform_ac": "F1NSL4-1", "url": "https://www.uniprot.org/uniprotkb/F1NSL4/entry#F1NSL4-1", "sequence": { "sequence": "MAAPGSEKSSKKKTEKKLAAREEAKLLAGFMGVMNSMRKQRTLCDVILMVQERRIPAHRVVLASASHFFNLMFTTNMLESKSFEVELKDAEPDIIEQLVEFAYTARISVNSNNVQSLLDAANQYQIEPVKKMCVDFLKEQVDASNCLGISVLAECLDCPELKATADDFIHQHFTEVYKTDEFLQLDVKRVTHLLNQDTLTVRAEDQVYDAAVRWLKYDEPNRQPYMVDILAKVRFPLISKNFLSKTVQAEPLIQDNPECLKMVISGMRYHLLSPEDREELVEGTRPRRKKHDYRIALFGGSQPQSCRYFNPKDYSWTDIRCPFEKRRDAACVFWDNVVYILGGSQLFPIKRMDCYNVVKDSWYSKLGPPTPRDSLAACAAEGKIYTSGGSEVGNSALYLFECYDTRTESWHTKPSMLTQRCSHGMVEANGLIYVCGGSLGNNVSGRVLNSCEVYDPATETWTELCPMIEARKNHGLVFVKDKIFAVGGQNGLGGLDNVEYYDIKMNEWKMVSPMPWKGVTVKCAAVGSIVYVLAGFQGVGRLGHILEYNTETDKWIANSKVRAFPVTSCLICVVDTCGANEETLET", "length": 586, "header": "tr|F1NSL4-1|F1NSL4_CHICK Isoform 1 of Kelch-like protein 7 OS=Gallus gallus OX=9031 GN=KLHL7 PE=4 SV=1 CANONICAL=F1NSL4-1" }, "locus": { "chromosome": "2", "start_pos": 30884659, "end_pos": 30861432, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010003221.1", "url": "https://www.ensembl.org/id/ENSGALT00010003221.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010001678.1", "url": "https://www.ensembl.org/id/ENSGALP00010001678.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:420612", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420612", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "Q5XHZ6-1", "protein_name": "Kelch-like protein 7", "gene_name": "Klhl7", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MATSGVEKSSKKKTEKKLAAREEAKLLAGFMGVMNNMRKQRTLCDVILMVQERKIPAHRVVLAAASHFFNLMFTTNMLESKSFEVELKDAEPDIIEQLVEFAYTARISVNSNNVQSLLDAANQYQIEPVKKMCVDFLKEQVDASNCLGISVLAECLDCPELKSTADDFIHQHFTEVYKTDEFLQLDVKRVTHLLSQDTLTVRAEDQVYDAAVRWLKYDEPNRQPFMVDILAKVRFPLISKNFLSKTVQAEPLIQDNPECLKMVISGMRYHLLSPEDREELAGGTRPRRKKHDYRIALFGGSQPQSCRYFNPKDYSWTDIRCPFEKRRDAACVFWDNVVYILGGSQLFPIKRMDCYNVVKDSWYSKLGPPTPRDSLAACAAEGKIYTSGGSEVGNSALYLFECYDTRTESWHTKPSMLTQRCSHGMVEANGLIYVCGGSLGNNVSGRVLSSCEVYDPATETWTELCSMIEPRKNHGLVFVKDKIFAVGGQNGLGGLDNVEYYDIKLNEWKMVSPMPWRGVTVKCAAVGSVIYVLAGFQGVGRLGHILEYNTETDKWVANSKVRAFPVTSCLICVVDTCGANEETLET", "length": 586 }, "evidence": [ { "id": "F1NSL4", "url": "https://omabrowser.org/oma/group/F1NSL4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8BUL5-1", "protein_name": "Kelch-like protein 7", "gene_name": "Klhl7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MATSGVEKSSKKKTEKKLAAREEAKLLAGFMGVMNNMRKQRTLCDVILTVQERKIPAHRVVLAAASHFFNLMFTTNMLESKSFEVELKDAEPDIIEQLVEFAYTARISVNSNNVQSLLDAANQYQIEPVKKMCVDFLKEQVDASNCLGISVLAECLDCPELKATADDFIHQHFTEVYKTDEFLQLDVKRVTHLLSQDTLTVRAEDQVYDAAVRWLKYDEPNRQPFMVDILAKVRFPLISKNFLSKTVQAEPLIQDNPECLKMVISGMRYHLLSPEDREELAGGTRPRRKKHDYRIALFGGSQPQSCRYFNPKDYSWTDIRCPFEKRRDAACVFWDNVVYILGGSQLFPIKRMDCYNVVKDSWYSKLGPPTPRDSLAACAAEGKIYTSGGSEVGNSALYLFECYDTRTESWHTKPSMLTQRCSHGMVEANGLIYVCGGSLGNNVSGRVLSSCEVYDPATETWTELCSMIEPRKNHGLVFVKDKIFAVGGQNGLGGLDNVEYYDIKLNEWKMVSPMPWRGVTVKCAAVGSVIYVLAGFQGVGRLGHILEYNTETDKWIANSKVRAFPVTSCLICVVDTCGANEETLET", "length": 586 }, "evidence": [ { "id": "F1NSL4", "url": "https://omabrowser.org/oma/group/F1NSL4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8IXQ5-1", "protein_name": "Kelch-like protein 7", "gene_name": "KLHL7", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAASGVEKSSKKKTEKKLAAREEAKLLAGFMGVMNNMRKQKTLCDVILMVQERKIPAHRVVLAAASHFFNLMFTTNMLESKSFEVELKDAEPDIIEQLVEFAYTARISVNSNNVQSLLDAANQYQIEPVKKMCVDFLKEQVDASNCLGISVLAECLDCPELKATADDFIHQHFTEVYKTDEFLQLDVKRVTHLLNQDTLTVRAEDQVYDAAVRWLKYDEPNRQPFMVDILAKVRFPLISKNFLSKTVQAEPLIQDNPECLKMVISGMRYHLLSPEDREELVDGTRPRRKKHDYRIALFGGSQPQSCRYFNPKDYSWTDIRCPFEKRRDAACVFWDNVVYILGGSQLFPIKRMDCYNVVKDSWYSKLGPPTPRDSLAACAAEGKIYTSGGSEVGNSALYLFECYDTRTESWHTKPSMLTQRCSHGMVEANGLIYVCGGSLGNNVSGRVLNSCEVYDPATETWTELCPMIEARKNHGLVFVKDKIFAVGGQNGLGGLDNVEYYDIKLNEWKMVSPMPWKGVTVKCAAVGSIVYVLAGFQGVGRLGHILEYNTETDKWVANSKVRAFPVTSCLICVVDTCGANEETLET", "length": 586 }, "evidence": [ { "id": "F1NSL4", "url": "https://omabrowser.org/oma/group/F1NSL4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "F1NSL4", "url": "https://www.uniprot.org/uniprotkb/F1NSL4" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "F1NSL4", "url": "https://www.uniprot.org/uniprotkb/F1NSL4" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1NSL4", "url": "https://www.uniprot.org/uniprotkb/F1NSL4" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F1NSL4", "url": "https://www.uniprot.org/uniprotkb/F1NSL4" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "F1NSL4", "url": "https://www.uniprot.org/uniprotkb/F1NSL4" } ], "pmid": "" }, { "name": "Cul3-RING ubiquitin ligase complex", "id": "GO:0031463", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031463", "evidence": [ { "database": "UniProtKB", "id": "F1NSL4", "url": "https://www.uniprot.org/uniprotkb/F1NSL4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "protein homodimerization activity", "id": "GO:0042803", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042803", "evidence": [ { "database": "UniProtKB", "id": "F1NSL4", "url": "https://www.uniprot.org/uniprotkb/F1NSL4" } ], "pmid": "" }, { "name": "ubiquitin-like ligase-substrate adaptor activity", "id": "GO:1990756", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990756", "evidence": [ { "database": "UniProtKB", "id": "F1NSL4", "url": "https://www.uniprot.org/uniprotkb/F1NSL4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "proteasome-mediated ubiquitin-dependent protein catabolic process", "id": "GO:0043161", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043161", "evidence": [ { "database": "UniProtKB", "id": "F1NSL4", "url": "https://www.uniprot.org/uniprotkb/F1NSL4" } ], "pmid": "" }, { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "F1NSL4", "url": "https://www.uniprot.org/uniprotkb/F1NSL4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 442, "end_pos": 444, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1NSL4-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 586, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1NSL4-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1NSL4" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1NSL4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NSL4" }, { "id": "PS50097", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50097" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "BTB", "eco_id": "ECO_0000259", "start_pos": 44, "end_pos": 111, "start_aa": "Cys", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 442, "end_pos": 444 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1NQX8-1", "uniprot_ac": "F1NQX8", "uniprot_id": "F1NQX8_CHICK", "mass": { "chemical_mass": 89789.0, "monoisotopic_mass": 89789.0 }, "refseq": { "ac": "XP_015127980", "name": "zinc finger X-chromosomal protein isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015127980" }, "gene_names": [ { "name": "ZFX", "type": "recommended", "evidence": [ { "id": "F1NQX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NQX8" } ] }, { "name": "ZFX", "type": "synonym", "evidence": [ { "id": "XP_015127980", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015127980" } ] } ], "protein_names": [ { "name": "Zinc finger protein X-linked", "type": "synonym", "evidence": [ { "id": "F1NQX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NQX8/entry#names_and_taxonomy" } ] }, { "name": "zinc finger X-chromosomal protein isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015127980", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015127980" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015127980", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015127980" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NQX8", "url": "https://www.uniprot.org/uniprotkb/F1NQX8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ZFX", "url": "https://www.uniprot.org/uniprotkb/F1NQX8", "locus": {} } ], "crossref": [ { "id": "F1NQX8", "url": "https://alphafold.ebi.ac.uk/entry/F1NQX8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000016327", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000016327", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "418596", "url": "https://www.ncbi.nlm.nih.gov/gene/418596", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006794", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006794", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050527", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050527", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:418596", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418596", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PDIEHME", "url": "https://omabrowser.org/oma/group/PDIEHME/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XHY3", "url": "https://www.orthodb.org/?gene=A0A8V0XHY3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NQX8", "url": "https://www.orthodb.org/?gene=F1NQX8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24388", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24388", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24388:SF104", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24388:SF104", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24393", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24393", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24393:SF140", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24393:SF140", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF04704", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04704", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13909", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13909", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015127980", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015127980", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0XHY3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XHY3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XHY3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XHY3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NQX8", "url": "https://www.uniprot.org/uniprotkb/F1NQX8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NQX8-1", "url": "https://www.uniprot.org/uniprotkb/F1NQX8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDEDGLELQPHEPNAFFDPTGADATHMDGDQIVVEVQETVFVSDVVDSDITVHNFVPDDPDSVVIQDVIEDVVIEDVQCPDIMEEPDVSETVIIPEQVLDTDVAEEVSLAHCTVPDDVLASDITAEAMSIPEHVLTSESMHVPEVGHVEHVVHDNVEEADIVTDTLGTDVVSEEVLVADCASEAVIDANGIPVEHQDEKGNCEDYLMISLDDAGKIEHEGSAEITMEAESESGSCKVDGICPEVIKVYIFKADPGEDDLGGTVDVVESEPENDHAVGLLDQNSSIRIPREKMVYMTVNDSQHEDEDLNVAEIADEVYMEVIVGEEDAAVAHEQQIDDNEIKTFMPIAWAAAYGNNNDGIESRNGTASALLHIDESAGLGRLAKQKPKKKRRPESRQYQTAIIIGPDGHPLTVYPCMICGKKFKSRGFLKRHMKNHPEHLLTKKKYRCTDCDYTTNKKISLHNHLESHKLTNKTEKLIERDECGKSFSHAGALFAHKMVHRDKGVNKMHKCKFCDYETAEQGLLSHHLLAVHSKNFPHICVECGKGFRHPSELKKHMRIHTGEKPYQCQYCEYRSADSSNLKTHVKTKHSKETSSKCDICFQTFSDTKELQQHTLMHQESKTHQCLHCDHKSSNSSDLKRHIISVHTKDYPHKCDMCDKGFHRPSELKKHVAAHKGKKLHQCRHCDFKIADPFILSRHILSVHTKDLPFRCKRCRKGFRQQNELKKHMKTHSGRKVYQCEYCEYSTTDASGFKRHVISIHTKDYPHRCEYCKKGFRRPSEKNQHIMRHHKDVGLP", "length": 794, "header": "tr|F1NQX8-1|F1NQX8_CHICK Isoform 1 of Zinc finger protein X-linked OS=Gallus gallus OX=9031 GN=ZFX PE=3 SV=2 CANONICAL=F1NQX8-1" }, "isoforms": [ { "isoform_ac": "A0A8V0XHY3-1", "url": "https://www.uniprot.org/uniprotkb/F1NQX8/entry#A0A8V0XHY3-1", "sequence": { "sequence": "MDEDGLELQPHEPNAFFDPTADATHMDGDQIVVEVQETVFVSDVVDSDITVHNFVPDDPDSVVIQDVIEDVVIEDVQCPDIMEEPDVSETVIIPEQVLDTDVAEEVSLAHCTVPDDVLASDITAEAMSIPEHVLTSESMHVPEVGHVEHVVHDNVEEADIVTDTLGTDVVSEEVLVADCASEAVIDANGIPVEHQDEKGNCEDYLMISRKCLGGTVDVVESEPENDHAVGLLDQNSSIRIPREKMVYMTVNDSQHEDEDLNVAEIADEVYMEVIVGEEDAAVAHEQQIDDNEIKTFMPIAWAAAYGNNNDGIESRNGTASALLHIDESAGLGRLAKQKPKKKRRPESRQYQTAIIIGPDGHPLTVYPCMICGKKFKSRGFLKRHMKNHPEHLLTKKKYRCTDCDYTTNKKISLHNHLESHKLTNKTEKLIERDECGKSFSHAGALFAHKMVHRDKGVNKMHKCKFCDYETAEQGLLSHHLLAVHSKNFPHICVECGKGFRHPSELKKHMRIHTGEKPYQCQYCEYRSADSSNLKTHVKTKHSKETSSKCDICFQTFSDTKELQQHTLMHQESKTHQCLHCDHKSSNSSDLKRHIISVHTKDYPHKCDMCDKGFHRPSELKKHVAAHKGKKLHQCRHCDFKIADPFILSRHILSVHTKDLPFRCKRCRKGFRQQNELKKHMKTHSGRKVYQCEYCEYSTTDASGFKRHVISIHTKDYPHRCEYCKKGFRRPSEKNQHIMRHHKDVGLP", "length": 747, "header": "tr|A0A8V0XHY3-1|A0A8V0XHY3_CHICK Computationally mapped isoform of Zinc finger protein X-linked OS=Gallus gallus OX=9031 GN=ZFX PE=3 SV=1 CANONICAL=F1NQX8-1" }, "locus": { "chromosome": "1", "start_pos": 118313189, "end_pos": 118298808, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010007123.1", "url": "https://www.ensembl.org/id/ENSGALT00010007123.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010004303.1", "url": "https://www.ensembl.org/id/ENSGALP00010004303.1" } ] } }, { "isoform_ac": "F1NQX8-1", "url": "https://www.uniprot.org/uniprotkb/F1NQX8/entry#F1NQX8-1", "sequence": { "sequence": "MDEDGLELQPHEPNAFFDPTGADATHMDGDQIVVEVQETVFVSDVVDSDITVHNFVPDDPDSVVIQDVIEDVVIEDVQCPDIMEEPDVSETVIIPEQVLDTDVAEEVSLAHCTVPDDVLASDITAEAMSIPEHVLTSESMHVPEVGHVEHVVHDNVEEADIVTDTLGTDVVSEEVLVADCASEAVIDANGIPVEHQDEKGNCEDYLMISLDDAGKIEHEGSAEITMEAESESGSCKVDGICPEVIKVYIFKADPGEDDLGGTVDVVESEPENDHAVGLLDQNSSIRIPREKMVYMTVNDSQHEDEDLNVAEIADEVYMEVIVGEEDAAVAHEQQIDDNEIKTFMPIAWAAAYGNNNDGIESRNGTASALLHIDESAGLGRLAKQKPKKKRRPESRQYQTAIIIGPDGHPLTVYPCMICGKKFKSRGFLKRHMKNHPEHLLTKKKYRCTDCDYTTNKKISLHNHLESHKLTNKTEKLIERDECGKSFSHAGALFAHKMVHRDKGVNKMHKCKFCDYETAEQGLLSHHLLAVHSKNFPHICVECGKGFRHPSELKKHMRIHTGEKPYQCQYCEYRSADSSNLKTHVKTKHSKETSSKCDICFQTFSDTKELQQHTLMHQESKTHQCLHCDHKSSNSSDLKRHIISVHTKDYPHKCDMCDKGFHRPSELKKHVAAHKGKKLHQCRHCDFKIADPFILSRHILSVHTKDLPFRCKRCRKGFRQQNELKKHMKTHSGRKVYQCEYCEYSTTDASGFKRHVISIHTKDYPHRCEYCKKGFRRPSEKNQHIMRHHKDVGLP", "length": 794, "header": "tr|F1NQX8-1|F1NQX8_CHICK Isoform 1 of Zinc finger protein X-linked OS=Gallus gallus OX=9031 GN=ZFX PE=3 SV=2 CANONICAL=F1NQX8-1" }, "locus": { "chromosome": "1", "start_pos": 118313189, "end_pos": 118298808, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010007119.1", "url": "https://www.ensembl.org/id/ENSGALT00010007119.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010004300.1", "url": "https://www.ensembl.org/id/ENSGALP00010004300.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:418596", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418596", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0ABK0M9W7-1", "protein_name": "Zinc finger protein X-linked", "gene_name": "Zfx", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDEDGLELQPQAPNSFFDATGAGATHMDGNQIVVEVQETVYVSDVVDSDITVHNYVPDDPDSVVIQDVIEDVVIEDVQCTDIMDEADVSETVIIPEQVLDSDVTEEVSLTHCTVPDDVLASDITSASISMPEHVLTSESIHVSDVSHVEHVVHDSVVEAEIVTDPLTADVVSEEVLVADCASEAVIDANGVPVNQQDEDKANCEDYLMISLDDAGKIEHDGSSGLTMDNETEIDPCKVDGTCPEVIKVYIFKADPGEDDLGGTVDIVESEPENEHGVELLDPNNSMRVPREKMVYMAVNDTQQEEEELNVAEIADEVYMEVIVGEEDAAAAAAAAVHEQQVEDNEMKTFMPIAWAAAYGNNSDGIENRNGTASALLHIDESAGLGRLAKQKPKKRRRPDSRQYQTAIIIGPDGHPLTVYPCMICGKKFKSRGFLKRHMKNHPEHLAKKKYRCTDCDYTTNKKISLHNHLESHKLTSKAEKAIECDECGKHFSHAGALFTHKMVHKEKGANKMHKCKFCEYETAEQGLLNRHLLAVHSKNFPHICVECGKGFRHPSELKKHMRIHTGEKPYECQYCEYRSADSSNLKTHVKTKHSKEMPFKCDICLLTFSDTKEVQQHALIHQESKTHQCLHCDHKSSNSSDLKRHIISVHTKDYPHKCDMCDKGFHRPSELKKHVAAHKGKKMHQCRHCDFKIADPFVLSRHILSVHTKDLPFRCKRCRKGFRQQSELKKHMKTHSGRKVYQCEYCEYSTTDASGFKRHVISIHTKDYPHRCEYCKKGFRRPSEKNQHIMRHHKEVGLP", "length": 799 }, "evidence": [ { "id": "F1NQX8", "url": "https://omabrowser.org/oma/group/F1NQX8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O62836-1", "protein_name": "Zinc finger X-chromosomal protein", "gene_name": "ZFX", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MDEDGLELQPQEPNSFFDTTGADATHMDGDQIVVEVQETVFVSDVVDSDITVHNFVPDDPDSVVIQDVIEDVVIEDVQCPDIMEEADVSETVIIPEQVLDSDVTEEVSLAHCTVPDDVLASDITSASMSMPEHVLTSESIHVSDIGHVEHVVHDSVVEAEIVTDPLTADVVSEEVLVADCASEAVIDANGIPVDQQEDDKGNCEDYLMISLDDAGKIEHDGSSGMTMDAESEIDPCKVDGTCPEVIKVYIFKADPGEDDLGGTVDIVESEPENDHGVELLDQNNSIRVPREKMVYMTVNDSQQEDEDLNVAEIADEVYMEVIVGEEDAAAAAAAAAAHEQQMDDNEIKTFMPIAWAAAYGNNSDGIENRNGTASALLHIDESAGLGRLAKQKPKKRRRPDSRQYQTAIIIGPDGHPLTVYPCMICGKKFKSRGFLKRHMKNHPEHLTKKKYRCTDCDYTTNKKISLHNHLESHKLTSKAEKAIECDECGKHFSHAGALFTHKMVHKEKGANKMHKCKFCEYETAEQGLLNRHLLAVHSKNFPHICVECGKGFRHPSELKKHMRIHTGEKPYQCQYCEYRSADSSNLKTHVKTKHSKEMPFKCDICLLTFSDTKEVQQHALIHQESKTHQCLHCDHKSSNSSDLKRHIISVHTKDYPHKCDMCDKGFHRPSELKKHVAAHKGKKMHQCRHCDFKIADPFVLSRHILSVHTKDLPFRCKRCRKGFRQQNELKKHMKTHSGRKVYQCEYCEYSTTDASGFKRHVISIHTKDYPHRCEYCKKGFRRPSEKNQHIMRHHKEVGLP", "length": 800 }, "evidence": [ { "id": "F1NQX8", "url": "https://omabrowser.org/oma/group/F1NQX8/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P17010-1", "protein_name": "Zinc finger X-chromosomal protein", "gene_name": "ZFX", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDEDGLELQQEPNSFFDATGADGTHMDGDQIVVEVQETVFVSDVVDSDITVHNFVPDDPDSVVIQDVIEDVVIEDVQCPDIMEEADVSETVIIPEQVLDSDVTEEVSLAHCTVPDDVLASDITSASMSMPEHVLTGDSIHVSDVGHVGHVGHVEHVVHDSVVEAEIVTDPLTTDVVSEEVLVADCASEAVIDANGIPVDQQDDDKGNCEDYLMISLDDAGKIEHDGSSGMTMDTESEIDPCKVDGTCPEVIKVYIFKADPGEDDLGGTVDIVESEPENDHGVELLDQNSSIRVPREKMVYMTVNDSQPEDEDLNVAEIADEVYMEVIVGEEDAAAAAAAAAVHEQQMDDNEIKTFMPIAWAAAYGNNSDGIENRNGTASALLHIDESAGLGRLAKQKPKKRRRPDSRQYQTAIIIGPDGHPLTVYPCMICGKKFKSRGFLKRHMKNHPEHLAKKKYRCTDCDYTTNKKISLHNHLESHKLTSKAEKAIECDECGKHFSHAGALFTHKMVHKEKGANKMHKCKFCEYETAEQGLLNRHLLAVHSKNFPHICVECGKGFRHPSELKKHMRIHTGEKPYQCQYCEYRSADSSNLKTHVKTKHSKEMPFKCDICLLTFSDTKEVQQHALIHQESKTHQCLHCDHKSSNSSDLKRHIISVHTKDYPHKCDMCDKGFHRPSELKKHVAAHKGKKMHQCRHCDFKIADPFVLSRHILSVHTKDLPFRCKRCRKGFRQQSELKKHMKTHSGRKVYQCEYCEYSTTDASGFKRHVISIHTKDYPHRCEYCKKGFRRPSEKNQHIMRHHKEVGLP", "length": 805 }, "evidence": [ { "id": "F1NQX8", "url": "https://omabrowser.org/oma/group/F1NQX8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P17012-1", "protein_name": "Zinc finger X-chromosomal protein", "gene_name": "Zfx", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDEDGLELQQQAPNSFFDATGAGATHMDGNQIVVEVQETVYVSDVVDSDITVHNYVPDDPDSVVIQDVIEDVVIEDVQCTDIMDEADVSETVIIPEQVLDSDVTEEVSLTHCTVPDDVLASDITSASISMPEHVLTSESIHVSDVGHVEHVVHDSVVEAEIVTDPLAADVVSEEVLVADCASEAVIDANGIPVNQQDEEKNNCEDYLMISLDDAGKIEHDGSSGLTMDNETEIDPCKVDGTCPEVIKVYIFKADPGEDDLGGTVDIVESEPENEHGVELLDPNNSIRVPREKMVYMAVNDSQQEEEELNVAEIADEVYMEVIVGEEDAAAAAAAAVHEQQVEDNEMKTFMPIAWAAAYGNNSDGIENRNGTASALLHIDESAGLGRLAKQKPKKRRRPDSRQYQTAIIIGPDGHPLTVYPCMICGKKFKSRGFLKRHMKNHPEHLAKKKYRCTDCDYTTNKKISLHNHLESHKLTSKAEKAIECDECGKHFSHAGALFTHKMVHKEKGANKMHKCKFCEYETAEQGLLNRHLLAVHSKNFPHICVECGKGFRHPSELKKHMRIHTGEKPYECQYCEYRSADSSNLKTHVKTKHSKEMPFKCDICLLTFSDTKEVQQHALVHQESKTHQCLHCDHKSSNSSDLKRHIISVHTKDYPHKCDMCDKGFHRPSELKKHVAAHKGKKMHQCRHCDFKIADPFVLSRHILSVHTKDLPFRCKRCRKGFRQQSELKKHMKTHSGRKVYQCEYCEYSTTDASGFKRHVISIHTKDYPHRCEYCKKGFRRPSEKNQHIMRHHKEVGLP", "length": 799 }, "evidence": [ { "id": "F1NQX8", "url": "https://omabrowser.org/oma/group/F1NQX8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "F1NQX8", "url": "https://www.uniprot.org/uniprotkb/F1NQX8" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "F1NQX8", "url": "https://www.uniprot.org/uniprotkb/F1NQX8" } ], "pmid": "" }, { "name": "RNA polymerase II transcription regulatory region sequence-specific DNA binding", "id": "GO:0000977", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000977", "evidence": [ { "database": "UniProtKB", "id": "F1NQX8", "url": "https://www.uniprot.org/uniprotkb/F1NQX8" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "F1NQX8", "url": "https://www.uniprot.org/uniprotkb/F1NQX8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1NQX8", "url": "https://www.uniprot.org/uniprotkb/F1NQX8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "F1NQX8", "url": "https://www.uniprot.org/uniprotkb/F1NQX8" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "F1NQX8", "url": "https://www.uniprot.org/uniprotkb/F1NQX8" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "F1NQX8", "url": "https://www.uniprot.org/uniprotkb/F1NQX8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 282, "end_pos": 284, "annotation": "n_glycosylation_sequon" }, { "start_pos": 298, "end_pos": 300, "annotation": "n_glycosylation_sequon" }, { "start_pos": 363, "end_pos": 365, "annotation": "n_glycosylation_sequon" }, { "start_pos": 471, "end_pos": 473, "annotation": "n_glycosylation_sequon" }, { "start_pos": 633, "end_pos": 635, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1NQX8-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 794, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1NQX8-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1NQX8" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1NQX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NQX8" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 413, "end_pos": 435, "start_aa": "Tyr", "end_aa": "His", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 282, "end_pos": 284 }, { "start_pos": 298, "end_pos": 300 }, { "start_pos": 363, "end_pos": 365 }, { "start_pos": 471, "end_pos": 473 }, { "start_pos": 633, "end_pos": 635 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1NKK8-1", "uniprot_ac": "F1NKK8", "uniprot_id": "F1NKK8_CHICK", "mass": { "chemical_mass": 62363.0, "monoisotopic_mass": 62363.0 }, "refseq": {}, "gene_names": [ { "name": "NECTIN3", "type": "recommended", "evidence": [ { "id": "F1NKK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NKK8" } ] } ], "protein_names": [ { "name": "Nectin-3", "type": "recommended", "evidence": [ { "id": "F1NKK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NKK8/entry#names_and_taxonomy" } ] }, { "name": "Nectin cell adhesion molecule 3", "type": "synonym", "evidence": [ { "id": "F1NKK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NKK8/entry#names_and_taxonomy" } ] }, { "name": "Poliovirus receptor-related protein 3", "type": "synonym", "evidence": [ { "id": "F1NKK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NKK8/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NKK8", "url": "https://www.uniprot.org/uniprotkb/F1NKK8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "NECTIN3", "url": "https://www.uniprot.org/uniprotkb/F1NKK8", "locus": { "chromosome": "1", "start_pos": 88503941, "end_pos": 88441627, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010005035", "url": "https://www.ensembl.org/id/ENSGALG00010005035" } ] } } ], "crossref": [ { "id": "F1NKK8", "url": "https://alphafold.ebi.ac.uk/entry/F1NKK8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000015367", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000015367", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd05887", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05887", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd07704", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07704", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "418415", "url": "https://www.ncbi.nlm.nih.gov/gene/418415", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003598", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003598", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013106", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013106", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013151", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013151", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013162", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013162", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033319", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033319", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033320", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033320", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051427", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051427", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "NEITHQR", "url": "https://omabrowser.org/oma/group/NEITHQR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XIX6", "url": "https://www.orthodb.org/?gene=A0A8V0XIX6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XRC6", "url": "https://www.orthodb.org/?gene=A0A8V0XRC6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NKK8", "url": "https://www.orthodb.org/?gene=F1NKK8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23277", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23277", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23277:SF12", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23277:SF12", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00047", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00047", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07686", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07686", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08205", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08205", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13927", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13927", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-418990", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-418990", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-420597", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-420597", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0XIX6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XIX6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XIX6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XIX6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XRC6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XRC6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XRC6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XRC6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NKK8", "url": "https://www.uniprot.org/uniprotkb/F1NKK8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NKK8-1", "url": "https://www.uniprot.org/uniprotkb/F1NKK8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAIGAVSRVSPAPIGRRELFPAAGASPRWWWWQQRRRRAGSALPPGLGLLGLVFSRFCCSALAGPVVDPHVTAVWGKKVALKCIIDVNETITQVSWEKIHGKTSETIAVHHPEYGISIQEKYQGKVSFKNYSLTDATIILKNVSFSDAGEYICKAVTFPLGNSQSSITVTVLVEPVVSLTKGPNPLIDGANQTIAAICTAATGKPAAEIDWEGGLGEMESSSTLFPNETVTVISQYTIIPTRFARGRRITCIVRHPALEKEIRFSHVLDIQYAPEVSVTGYDGNWFIGRENVQLRCNADANPLPMEFMWTRLDGQWPEGLLSVNNTLQFSSPLTYNYTGTYICKVTNSLGQRSDQKTIYILDPPTTTTRLPTVPWHPSTDGITGLATEPRIIDFPSSTLPAMQEDTWGTVIGSAVGGALFLILVSVLVGIICYRRRRTFRGDYFAKNYIPPSDMQKESQIDVLQSDDVDSYPDSIKKEIKHPMNSLISKDYLEDPEKPEWNNIDNINRYQERYERPMDYYESGTLGMKYMGGDCYDDNEEDFVSHIDGSVISRREWYV", "length": 559, "header": "tr|F1NKK8-1|F1NKK8_CHICK Isoform 1 of Nectin-3 OS=Gallus gallus OX=9031 GN=NECTIN3 PE=1 SV=4 CANONICAL=F1NKK8-1" }, "isoforms": [ { "isoform_ac": "A0A8V0XIX6-1", "url": "https://www.uniprot.org/uniprotkb/F1NKK8/entry#A0A8V0XIX6-1", "sequence": { "sequence": "MAAIGAVSRVSPAPIGRRELFPAAGASPRWWWWQQRRRRAGSALPPGLGLLGLVFSRFCCSALAGPVVDPHVTAVWGKKVALKCIIDVNETITQVSWEKIHGKTSETIAVHHPEYGISIQEKYQGKVSFKNYSLTDATIILKNVSFSDAGEYICKAVTFPLGNSQSSITVTVLVEPVVSLTKGPNPLIDGANQTIAAICTAATGKPAAEIDWEGGLGEMESSSTLFPNETVTVISQYTIIPTRFARGRRITCIVRHPALEKEIRFSHVLDIQYAPEVSVTGYDGNWFIGRENVQLRCNADANPLPMEFMWTRLDGQWPEGLLSVNNTLQFSSPLTYNYTGTYICKVTNSLGQRSDQKTIYILDMPFKQTSSVAVAGAVIGAVLALFIITIFVTVLLTPRKKRPSYLDKVIDLPPTHKPSSHEERAFSLPQKETIIQKEHLALQSQYGEKDTGNLQHVKAVNERQLICEAEELQEQQCLQHMYPVYQQTYYKNWSSRHPQNSGPGRVYINPREHYV", "length": 515, "header": "tr|A0A8V0XIX6-1|A0A8V0XIX6_CHICK Computationally mapped isoform of Nectin-3 OS=Gallus gallus OX=9031 GN=NECTIN3 PE=1 SV=1 CANONICAL=F1NKK8-1" }, "locus": { "chromosome": "1", "start_pos": 88500866, "end_pos": 88441720, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010011869.1", "url": "https://www.ensembl.org/id/ENSGALT00010011869.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010006646.1", "url": "https://www.ensembl.org/id/ENSGALP00010006646.1" } ] } }, { "isoform_ac": "A0A8V0XRC6-1", "url": "https://www.uniprot.org/uniprotkb/F1NKK8/entry#A0A8V0XRC6-1", "sequence": { "sequence": "MAAIGAVSRVSPAPIGRRELFPAAGASPRWWWWQQRRRRAGSALPPGLGLLGLVFSRFCCSALAGPVVDPHVTAVWGKKVALKCIIDVNETITQVSWEKIHGKTSETIAVHHPEYGISIQEKYQGKVSFKNYSLTDATIILKNVSFSDAGEYICKAVTFPLGNSQSSITVTVLVEPVVSLTKGPNPLIDGANQTIAAICTAATGKPAAEIDWEGGLGEMESSSTLFPNETVTVISQYTIIPTRFARGRRITCIVRHPALEKEIRFSHVLDIQYAPEVSVTGYDGNWFIGRENVQLRCNADANPLPMEFMWTRLDGQWPEGLLSVNNTLQFSSPLTYNYTGTYICKVTNSLGQRSDQKTIYILDMPFKQTSSVAVAGAVIGAVLALFIITIFVTVLLTPRKKRPSYLDKVIDLPPTHKPSSHEERAFSLPQKETIIQADVKPVPPKQHKRER", "length": 451, "header": "tr|A0A8V0XRC6-1|A0A8V0XRC6_CHICK Computationally mapped isoform of Nectin-3 OS=Gallus gallus OX=9031 GN=NECTIN3 PE=1 SV=1 CANONICAL=F1NKK8-1" }, "locus": { "chromosome": "1", "start_pos": 88493998, "end_pos": 88441720, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010011863.1", "url": "https://www.ensembl.org/id/ENSGALT00010011863.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010006643.1", "url": "https://www.ensembl.org/id/ENSGALP00010006643.1" } ] } }, { "isoform_ac": "F1NKK8-1", "url": "https://www.uniprot.org/uniprotkb/F1NKK8/entry#F1NKK8-1", "sequence": { "sequence": "MAAIGAVSRVSPAPIGRRELFPAAGASPRWWWWQQRRRRAGSALPPGLGLLGLVFSRFCCSALAGPVVDPHVTAVWGKKVALKCIIDVNETITQVSWEKIHGKTSETIAVHHPEYGISIQEKYQGKVSFKNYSLTDATIILKNVSFSDAGEYICKAVTFPLGNSQSSITVTVLVEPVVSLTKGPNPLIDGANQTIAAICTAATGKPAAEIDWEGGLGEMESSSTLFPNETVTVISQYTIIPTRFARGRRITCIVRHPALEKEIRFSHVLDIQYAPEVSVTGYDGNWFIGRENVQLRCNADANPLPMEFMWTRLDGQWPEGLLSVNNTLQFSSPLTYNYTGTYICKVTNSLGQRSDQKTIYILDPPTTTTRLPTVPWHPSTDGITGLATEPRIIDFPSSTLPAMQEDTWGTVIGSAVGGALFLILVSVLVGIICYRRRRTFRGDYFAKNYIPPSDMQKESQIDVLQSDDVDSYPDSIKKEIKHPMNSLISKDYLEDPEKPEWNNIDNINRYQERYERPMDYYESGTLGMKYMGGDCYDDNEEDFVSHIDGSVISRREWYV", "length": 559, "header": "tr|F1NKK8-1|F1NKK8_CHICK Isoform 1 of Nectin-3 OS=Gallus gallus OX=9031 GN=NECTIN3 PE=1 SV=4 CANONICAL=F1NKK8-1" }, "locus": { "chromosome": "1", "start_pos": 88485067, "end_pos": 88441720, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010011857.1", "url": "https://www.ensembl.org/id/ENSGALT00010011857.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010006640.1", "url": "https://www.ensembl.org/id/ENSGALP00010006640.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-418990", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-418990", "resource": "Reactome", "description": "Adherens junctions interactions" }, { "id": "R-GGA-420597", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-420597", "resource": "Reactome", "description": "Nectin/Necl trans heterodimerization" } ], "orthologs": [ { "uniprot_canonical_ac": "Q9JLB9-1", "protein_name": "Nectin-3", "gene_name": "Nectin3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MARTPGPAPLCPGGGKAQLSSAFPPAAGLLLPAPTPPPLLLLLIPLLLFSRLCGALAGSIIVEPHVTAVWGKNVSLKCLIEVNETITQISWEKIHGKSTQTVAVHHPQYGFSVQGDYQGRVLFKNYSLNDATITLHNIGFSDSGKYICKAVTFPLGNAQSSTTVTVLVEPTVSLIKGPDSLIDGGNETVAAVCVAATGKPVAQIDWEGDLGEMESSTTSFPNETATIVSQYKLFPTRFARGRRITCVVKHPALEKDIRYSFILDIQYAPEVSVTGYDGNWFVGRKGVNLKCNADANPPPFKSVWSRLDGQWPDGLLASDNTLHFVHPLTVNYSGVYVCKVSNSLGQRSDQKVIYISDPPTTTTLQPTVQWHSSPADVQDIATEHKKLPFPLSTLATLKDDTIGTIIASVVGGALFLVLVSILAGVFCYRRRRTFRGDYFAKNYIPPSDMQKESQIDVLHQDELDSYPDSVKKENKNPVNNLIRKDYLEEPEKTQWNNVENLTRFERPMDYYEDLKMGMKFVSDERYNESEDGLVSHVDGSVISRREWYV", "length": 549 }, "evidence": [ { "id": "F1NKK8", "url": "https://omabrowser.org/oma/group/F1NKK8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9NQS3-1", "protein_name": "Nectin-3", "gene_name": "NECTIN3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MARTLRPSPLCPGGGKAQLSSASLLGAGLLLQPPTPPPLLLLLFPLLLFSRLCGALAGPIIVEPHVTAVWGKNVSLKCLIEVNETITQISWEKIHGKSSQTVAVHHPQYGFSVQGEYQGRVLFKNYSLNDATITLHNIGFSDSGKYICKAVTFPLGNAQSSTTVTVLVEPTVSLIKGPDSLIDGGNETVAAICIAATGKPVAHIDWEGDLGEMESTTTSFPNETATIISQYKLFPTRFARGRRITCVVKHPALEKDIRYSFILDIQYAPEVSVTGYDGNWFVGRKGVNLKCNADANPPPFKSVWSRLDGQWPDGLLASDNTLHFVHPLTFNYSGVYICKVTNSLGQRSDQKVIYISDPPTTTTLQPTIQWHPSTADIEDLATEPKKLPFPLSTLATIKDDTIATIIASVVGGALFIVLVSVLAGIFCYRRRRTFRGDYFAKNYIPPSDMQKESQIDVLQQDELDSYPDSVKKENKNPVNNLIRKDYLEEPEKTQWNNVENLNRFERPMDYYEDLKMGMKFVSDEHYDENEDDLVSHVDGSVISRREWYV", "length": 549 }, "evidence": [ { "id": "F1NKK8", "url": "https://omabrowser.org/oma/group/F1NKK8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "adherens junction", "id": "GO:0005912", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005912", "evidence": [ { "database": "UniProtKB", "id": "F1NKK8", "url": "https://www.uniprot.org/uniprotkb/F1NKK8" } ], "pmid": "" }, { "name": "postsynaptic membrane", "id": "GO:0045211", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045211", "evidence": [ { "database": "UniProtKB", "id": "F1NKK8", "url": "https://www.uniprot.org/uniprotkb/F1NKK8" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F1NKK8", "url": "https://www.uniprot.org/uniprotkb/F1NKK8" } ], "pmid": "" }, { "name": "cell-cell contact zone", "id": "GO:0044291", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044291", "evidence": [ { "database": "UniProtKB", "id": "F1NKK8", "url": "https://www.uniprot.org/uniprotkb/F1NKK8" } ], "pmid": "" }, { "name": "apical junction complex", "id": "GO:0043296", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043296", "evidence": [ { "database": "UniProtKB", "id": "F1NKK8", "url": "https://www.uniprot.org/uniprotkb/F1NKK8" } ], "pmid": "" }, { "name": "postsynaptic density membrane", "id": "GO:0098839", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098839", "evidence": [ { "database": "UniProtKB", "id": "F1NKK8", "url": "https://www.uniprot.org/uniprotkb/F1NKK8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 7, "go_terms": [ { "name": "cell adhesion", "id": "GO:0007155", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007155", "evidence": [ { "database": "UniProtKB", "id": "F1NKK8", "url": "https://www.uniprot.org/uniprotkb/F1NKK8" } ], "pmid": "" }, { "name": "symbiont entry into host cell", "id": "GO:0046718", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046718", "evidence": [ { "database": "UniProtKB", "id": "F1NKK8", "url": "https://www.uniprot.org/uniprotkb/F1NKK8" } ], "pmid": "" }, { "name": "homophilic cell adhesion via plasma membrane adhesion molecules", "id": "GO:0007156", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007156", "evidence": [ { "database": "UniProtKB", "id": "F1NKK8", "url": "https://www.uniprot.org/uniprotkb/F1NKK8" } ], "pmid": "" }, { "name": "heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules", "id": "GO:0007157", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007157", "evidence": [ { "database": "UniProtKB", "id": "F1NKK8", "url": "https://www.uniprot.org/uniprotkb/F1NKK8" } ], "pmid": "" }, { "name": "cochlea morphogenesis", "id": "GO:0090103", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090103", "evidence": [ { "database": "UniProtKB", "id": "F1NKK8", "url": "https://www.uniprot.org/uniprotkb/F1NKK8" } ], "pmid": "" }, { "name": "establishment of protein localization to plasma membrane", "id": "GO:0061951", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061951", "evidence": [ { "database": "UniProtKB", "id": "F1NKK8", "url": "https://www.uniprot.org/uniprotkb/F1NKK8" } ], "pmid": "" }, { "name": "regulation of postsynapse assembly", "id": "GO:0150052", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0150052", "evidence": [ { "database": "UniProtKB", "id": "F1NKK8", "url": "https://www.uniprot.org/uniprotkb/F1NKK8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "F1NKK8", "url": "https://www.uniprot.org/uniprotkb/F1NKK8" } ], "pmid": "" }, { "name": "cell adhesion molecule binding", "id": "GO:0050839", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050839", "evidence": [ { "database": "UniProtKB", "id": "F1NKK8", "url": "https://www.uniprot.org/uniprotkb/F1NKK8" } ], "pmid": "" }, { "name": "protein homodimerization activity", "id": "GO:0042803", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042803", "evidence": [ { "database": "UniProtKB", "id": "F1NKK8", "url": "https://www.uniprot.org/uniprotkb/F1NKK8" } ], "pmid": "" }, { "name": "cell adhesion mediator activity", "id": "GO:0098631", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098631", "evidence": [ { "database": "UniProtKB", "id": "F1NKK8", "url": "https://www.uniprot.org/uniprotkb/F1NKK8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 131, "end_pos": 133, "annotation": "n_glycosylation_sequon" }, { "start_pos": 143, "end_pos": 145, "annotation": "n_glycosylation_sequon" }, { "start_pos": 192, "end_pos": 194, "annotation": "n_glycosylation_sequon" }, { "start_pos": 228, "end_pos": 230, "annotation": "n_glycosylation_sequon" }, { "start_pos": 325, "end_pos": 327, "annotation": "n_glycosylation_sequon" }, { "start_pos": 337, "end_pos": 339, "annotation": "n_glycosylation_sequon" }, { "start_pos": 89, "end_pos": 91, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1NKK8-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 559, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1NKK8-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1NKK8" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1NKK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NKK8" }, { "id": "PS50835", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50835" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ig-like", "eco_id": "ECO_0000259", "start_pos": 66, "end_pos": 171, "start_aa": "Pro", "end_aa": "Thr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 131, "end_pos": 133 }, { "start_pos": 143, "end_pos": 145 }, { "start_pos": 192, "end_pos": 194 }, { "start_pos": 228, "end_pos": 230 }, { "start_pos": 325, "end_pos": 327 }, { "start_pos": 337, "end_pos": 339 }, { "start_pos": 89, "end_pos": 91 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1NS24-1", "uniprot_ac": "F1NS24", "uniprot_id": "F1NS24_CHICK", "mass": { "chemical_mass": 98314.0, "monoisotopic_mass": 98314.0 }, "refseq": { "ac": "XP_418678", "name": "GATOR complex protein MIOS", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_418678" }, "gene_names": [ { "name": "MIOS", "type": "recommended", "evidence": [ { "id": "F1NS24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NS24" } ] }, { "name": "MIOS", "type": "synonym", "evidence": [ { "id": "XP_418678", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_418678" } ] } ], "protein_names": [ { "name": "GATOR complex protein MIOS", "type": "synonym", "evidence": [ { "id": "XP_418678", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_418678" } ] }, { "name": "Meiosis regulator for oocyte development", "type": "synonym", "evidence": [ { "id": "F1NS24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NS24/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052533.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Nov 16, 2006 this sequence version replaced XP_418678.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_418678", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_418678" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NS24", "url": "https://www.uniprot.org/uniprotkb/F1NS24" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MIOS", "url": "https://www.uniprot.org/uniprotkb/F1NS24", "locus": { "chromosome": "2", "start_pos": 24694051, "end_pos": 24679598, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010003915", "url": "https://www.ensembl.org/id/ENSGALG00010003915" } ] } } ], "crossref": [ { "id": "F1NS24", "url": "https://alphafold.ebi.ac.uk/entry/F1NS24", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000010699", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000010699", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd16691", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16691", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "420577", "url": "https://www.ncbi.nlm.nih.gov/gene/420577", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001680", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001680", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR031488", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031488", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036322", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036322", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037593", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037593", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR049092", "url": "https://www.ebi.ac.uk/interpro/entry/IPR049092", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:420577", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420577", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YWIASYL", "url": "https://omabrowser.org/oma/group/YWIASYL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XKQ0", "url": "https://www.orthodb.org/?gene=A0A8V0XKQ0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NS24", "url": "https://www.orthodb.org/?gene=F1NS24", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16453", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16453", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16453:SF9", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16453:SF9", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF17034", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17034", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21719", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21719", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21720", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21720", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-9639288", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9639288", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_418678", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_418678", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0XKQ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XKQ0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XKQ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XKQ0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NS24", "url": "https://www.uniprot.org/uniprotkb/F1NS24", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NS24-1", "url": "https://www.uniprot.org/uniprotkb/F1NS24-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSGSKPDILWAPHHVDRFVVCDSELSLYHIESAVSSELKAGSLRLSEETTATLLSINSDTPYLKCVAWYPKYDPECLLAVGQANGRVVLTSLGQDHNSKSKDLIGKEFVPKHARQCNTLAWNPLDSNWLAAGLDKHRADFSVLIWDISSKYAPETAVATEKVRLSTGDPEAGLVVTKPLYELGQNDACLSLCWLPRDQKLLLAGMHRNLAIFDLRNTSQKIFVNTKAVQGVTVDPYFHDRVASFYEGQVAIWDLRKFEKPVLTLTEQPKPLTKVAWCPTRTGLLATLTRDSNIIRLYDMQHTPTPIGDETEPTIIERSVQPCENYIASFAWHPTSQNRMVVVTPNRTMSDFTVFERISLAWSPVTSLMWACGRHLYECTEEGKASSLEKDIATKMRLRALSRYGLDTEQVWRNHLLAGNEDPQLKSLWYTLHFMKQYTEDMDQKLTGNKGPLVYAGIKSIVKSSLGTTENLRHSRSGSDRQADIIQYLSEERSLALQLCGWIKKGIDLDVEPFLNSLEQEGDWERAAAVALFNLDIRRAIQILNKGASSGKGDLNLNVVAMALSGYTDEKNSLWREMCSTLRLQLNNPYLCAMFAFLTSESGSYDGVLYENNVAVRDRVAFACKFLNDAQLNRFIEKLTNEMKDAGNLEGILLTGLTKDGVDLMESYVDRTGDVQTASYCMLQGSPSEVLKDERVQYWIENYRNLLDAWRFWHKRAEFDIHRSKLDPSSKPLAQVFVSCNFCGKSISYSCSAIPHQGRGFSQYGVSGSPTKSKVTSCPGCRKPLPRCALCLINMGTPVSSCPGGSKSDEKVDLSKDKKLAQFNNWFTWCHNCRHGGHAGHMLSWFRDHTECPVSACSCKCMQLDTTGNLIPAETVQA", "length": 877, "header": "tr|F1NS24-1|F1NS24_CHICK Isoform 1 of Meiosis regulator for oocyte development OS=Gallus gallus OX=9031 GN=MIOS PE=1 SV=4 CANONICAL=F1NS24-1" }, "isoforms": [ { "isoform_ac": "A0A8V0XKQ0-1", "url": "https://www.uniprot.org/uniprotkb/F1NS24/entry#A0A8V0XKQ0-1", "sequence": { "sequence": "MSGSKPDILWAPHHVDRFVVCDSELSLYHIESAVSSELKAGSLRLSEETTATLLSINSDTPYLKCVAWYPKYDPECLLAVGQANGRVVLTSLGQDHNSKSKDLIGKEFVPKHARQCNTLAWNPLDSNWLAAGLDKHRADFSVLIWDISSKYAPETAVATEKVRLSTGDPEAGLVVTKPLYELGQNDACLSLCWLPRDQKLLLAGMHRNLAIFDLRNTSQKIFVNTKAVQGVTVDPYFHDRVASFYEGQVAIWDLRKFEKPVLTLTEQPKPLTKVAWCPTRTGLLATLTRDSNIIRLYDMQHTPTPIGDETEPTIIERSVQPCENYIASFAWHPTSQNRMVVVTPNRTMSDFTVFERISLAWSPVTSLMWACGRHLYECTEEGKASSLEKDIATKMRLRALSRYGLDTEQVWRNHLLAGNEDPQLKSLWYTLHLKQYTEDMDQKLTGNKGPLVYAGIKSIVKSSLGTTENLRHSRSGSDRQADIIQYLSEERSLALQLCGWIKKGIDLDVEPFLNSLEQEGDWERAAAVALFNLDIRRAIQILNKGASSGKGDLNLNVVAMALSGYTDEKNSLWREMCSTLRLQLNNPYLCAMFAFLTSESGSYDGVLYENNVAVRDRVAFACKFLNDAQLNRFIEKLTNEMKDAGNLEGILLTGLTKDGVDLMESYVDRTGDVQTASYCMLQGSPSEVLKDERVQYWIENYRNLLDAWRFWHKRAEFDIHRSKLDPSSKPLAQVFVSCNFCGKSISYSCSAIPHQGRGFSQYGVSGSPTKSKVTSCPGCRKPLPRCALCLINMGTPVSSCPGGSKSDEKVDLSKDKKLAQFNNWFTWCHNCRHGGHAGHMLSWFRDHTECPVSACSCKCMQLDTTGNLIPAETVQA", "length": 876, "header": "tr|A0A8V0XKQ0-1|A0A8V0XKQ0_CHICK Computationally mapped isoform of Meiosis regulator for oocyte development OS=Gallus gallus OX=9031 GN=MIOS PE=1 SV=1 CANONICAL=F1NS24-1" }, "locus": { "chromosome": "2", "start_pos": 24691989, "end_pos": 24680763, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010009055.1", "url": "https://www.ensembl.org/id/ENSGALT00010009055.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010005356.1", "url": "https://www.ensembl.org/id/ENSGALP00010005356.1" } ] } }, { "isoform_ac": "F1NS24-1", "url": "https://www.uniprot.org/uniprotkb/F1NS24/entry#F1NS24-1", "sequence": { "sequence": "MSGSKPDILWAPHHVDRFVVCDSELSLYHIESAVSSELKAGSLRLSEETTATLLSINSDTPYLKCVAWYPKYDPECLLAVGQANGRVVLTSLGQDHNSKSKDLIGKEFVPKHARQCNTLAWNPLDSNWLAAGLDKHRADFSVLIWDISSKYAPETAVATEKVRLSTGDPEAGLVVTKPLYELGQNDACLSLCWLPRDQKLLLAGMHRNLAIFDLRNTSQKIFVNTKAVQGVTVDPYFHDRVASFYEGQVAIWDLRKFEKPVLTLTEQPKPLTKVAWCPTRTGLLATLTRDSNIIRLYDMQHTPTPIGDETEPTIIERSVQPCENYIASFAWHPTSQNRMVVVTPNRTMSDFTVFERISLAWSPVTSLMWACGRHLYECTEEGKASSLEKDIATKMRLRALSRYGLDTEQVWRNHLLAGNEDPQLKSLWYTLHFMKQYTEDMDQKLTGNKGPLVYAGIKSIVKSSLGTTENLRHSRSGSDRQADIIQYLSEERSLALQLCGWIKKGIDLDVEPFLNSLEQEGDWERAAAVALFNLDIRRAIQILNKGASSGKGDLNLNVVAMALSGYTDEKNSLWREMCSTLRLQLNNPYLCAMFAFLTSESGSYDGVLYENNVAVRDRVAFACKFLNDAQLNRFIEKLTNEMKDAGNLEGILLTGLTKDGVDLMESYVDRTGDVQTASYCMLQGSPSEVLKDERVQYWIENYRNLLDAWRFWHKRAEFDIHRSKLDPSSKPLAQVFVSCNFCGKSISYSCSAIPHQGRGFSQYGVSGSPTKSKVTSCPGCRKPLPRCALCLINMGTPVSSCPGGSKSDEKVDLSKDKKLAQFNNWFTWCHNCRHGGHAGHMLSWFRDHTECPVSACSCKCMQLDTTGNLIPAETVQA", "length": 877, "header": "tr|F1NS24-1|F1NS24_CHICK Isoform 1 of Meiosis regulator for oocyte development OS=Gallus gallus OX=9031 GN=MIOS PE=1 SV=4 CANONICAL=F1NS24-1" }, "locus": { "chromosome": "2", "start_pos": 24691989, "end_pos": 24680763, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010009053.1", "url": "https://www.ensembl.org/id/ENSGALT00010009053.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010005354.1", "url": "https://www.ensembl.org/id/ENSGALP00010005354.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:420577", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420577", "resource": "KEGG Pathway" }, { "id": "R-GGA-9639288", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9639288", "resource": "Reactome", "description": "Amino acids regulate mTORC1" } ], "orthologs": [ { "uniprot_canonical_ac": "D3Z9C0-1", "protein_name": "GATOR2 complex protein MIOS", "gene_name": "Mios", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSGTKPDILWAPHQVDRFVVCDSELSLYHVESAVNSELKAGSLRLSEDSAATLLSINSDTPYMKCVAWYLNYDPECLLAVGQANGRVVLTSLGQDHNSKFKDLIGKEFVPKHARQCNTLAWNPLDSNWLAAGLDKHRADFSVLIWDICSKYTPDIVPMEKVRLSAGEAETTLLVTKPLYELGQNDACLSLCWLPRDQKLLLAGMHRNLAIFDLRNTSQKMFVNTKAVQGVTVDPYFHDRVASFYEGQVAIWDLRKFEKPVLTLTEQPKPLTKVAWCPTRTGLLATLTRDSNIIRLYDMQHTPTPIGDETEPTIIERSVQPCDNYIASFAWHPTSQNRMIVVTPNRTMSDFTVFERISLAWSPITSLMWACGRHLYECAEEESDNTLEKDIATKMRLRALSRYGLDTEQVWRNHILAGNEDPQLKSLWYTLHLLMKQYTEEMDQKSPGNKGSLVYAGIKSIVKSSLGMVESSRHNWSGLDKQTDIQNLNEERILALQLCGWIKKGTDVDVGPFLNSLVQEGEWERAAAVALFNLDIRRAIQILNEGASSEKGDLNLNVVAMALSGYTDEKNSLWREMCSTLRLQLNNPYLCVMFAFLTSEAGAYDGVLYENKVAVRDRVAFACKFLGDAQLNKYIEKLTNEMKEAGNLEGILLTGLTKDGVDLMESYVDRTGDVQTASYCMLQGSPLDVLKDERVQYWIENYRNLLDAWRFWHKRAEFDIHRSKLDPSSKPLAQVFVSCNFCGKSISYSCSSVPHQGRGFSQYGVSGSPTKSKVTSCPGCRKPLPRCALCLINMGTPVSSCPGGSKSDEKVDLSKDKKLAQFNNWFTWCHNCRHGGHAGHMLSWFRDHAECPVSACTCKCMQLDTTGNLVPAETLQP", "length": 876 }, "evidence": [ { "id": "F1NS24", "url": "https://omabrowser.org/oma/group/F1NS24/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E1B899-1", "protein_name": "GATOR2 complex protein MIOS", "gene_name": "MIOS", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSGSKPDILWAPHQVDRFVVCDSELSLYHVESTVNSELKAGSLRLSEDSAATLLSINSETPYMKCVAWYLSYDPECLLAVGQANGRVVLTSLGQDHNSKFRDLIGKEFVPKHARQCNTLAWNPVDNNWLAAGLDKHRADFSVLIWDICSKYTPDIVPMEKVRLSVGETETSLLVTKPLYELGQNDACLSLCWLPRDQKLLLAGMHRNLAIFDLRNTSQKMFVNTKAVQGVTVDPYFHDRVASFYEGQVAIWDLRKFEKPVLTLTEQPKPLTKVAWCPTRTGLLATLTRDSNIIRLYDMQHTPTPIGDETEPTIIERSVQPCDNYIASFAWHPTSQNRMIVVTPNRTMSDFTVFERISLAWSPITSLMWACGRHLYECAEEENDNSLEKDIATKMRLRALSRYGLDTEQVWRNHILAGNEDPQLKSLWYTLHFMKQYTEDMDQKSPGNKGSLVYAGIKSIVKSSLGMVESSRHNWSGLDKQSDIQNLNEERILALQLCGWIKKGTDVDVGPFLNSLVQEGEWERAAAVALFNLDIRRAIQILNEGASSGKGDLNLNVVAMALSGYTDEKNSLWREMCSTLRLQLNNPYLCIMFAFLTSEAGSYDGVLYENKVAVRDRVAFACKFLSDSQLNRYIEKLTNEMKEAGNLEGILLTGLTKDGVDLMESYVDRTGDVQTASYCMLQGSPLDVLKDERVQYWIENYRNLLDAWRFWHKRAEFDIHRSKLDPSSKPLAQVFVSCNFCGKSISYSCSTVPHQGRGFSQYGVSGSPTKSKVTSCPGCRKPLPRCALCLINMGTPVSSCPGGSKSDEKVDLSKDKKLAQFNNWFTWCHNCRHGGHAGHMLSWFRDHAECPVSACTCKCMQLDTTGNLVPAETVQP", "length": 875 }, "evidence": [ { "id": "F1NS24", "url": "https://omabrowser.org/oma/group/F1NS24/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "G3HJI0-1", "protein_name": "GATOR2 complex protein MIOS", "gene_name": "Mios", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSGTKPDILWAPHQVDRFVVCDSELSLYHVESAVNSELKAGSLRLSEDSAATLLSINSDTPYMKCIAWYLSYDPECLLAVGQANGRVVLTSLGQDHNSKFKDLIGKEFVPKHARQCNTLAWNPLDSNWLAAGLDKHRADFSVLIWDICSKYTPDIVPMEKVRLSAGEAETTLLVTKPLYELGQNDACLSLCWLPRDQKLLLAGMHRNLAIFDLRNTSQKMFVNTKAVQGVTVDPYFHDRVASFYEGQVAIWDLRKFEKPVLTLTEQPKPLTKVAWCPTRTGLLATLTRDSNIIRLYDMQHTPTPIGDETEPTIIERSVQPCDNYIASFAWHPTSQNRMIVMTPNRTMSDFTVFERISLAWSPITSLMWACGRHLYECAEEESDNSLEKDIATKMRLRALSRYGLDTEQVWRNHILAGNEDPQLKSLWYTLHFMKQYTEDMDQKSPGNKGSLVYAGIKSIVKSSLGMVESSRHNWSGLDKQTDIQNLNEERILALQLCGWIKKGTDVDVGPFLNSLVQEGEWERAAAVALFNLDIRRAIQILNEGASSEKGDLNLNVVAMALSGYTDEKNSLWREMCSTLRLQLHNPYLCVMFAFLTSEAGAYDGVLYENKVAVRDRVAFACKFLGDTQLNKYIEKLTNEMKEAGNLEGILLTGLTKDGVDLMESYVDRTGDVQTASYCMLQGSPLDVLKDERVQYWIENYRNLLDAWRFWHKRAEFDIHRSKLDPSSKPLAQVFVSCNFCGKSISYSCSSVPHQGRGFSQYGVSGSPTKSKVTSCPGCRKPLPRCALCLINMGTPVSSCPGGSKSDEKVDLSKDKKLAQFNNWFTWCHNCRHGGHAGHMLSWFRDHAECPVSACTCKCMQLDTTGNLVPAETVQP", "length": 875 }, "evidence": [ { "id": "F1NS24", "url": "https://omabrowser.org/oma/group/F1NS24/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q551B5-1", "protein_name": "GATOR2 complex protein MIOS", "gene_name": "mios", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSQSSTRKRLIQWSPHNKSSFIVGSNDLRLYNFKFKDKNEKKNENNINNSNQYNQNNQQQQQQQIQQQQQQQQQQQQQQQQQQQQQQQQQQQQHDIYSPKSITSKYMETYNFDIEYPPDDWVPQEKKTISLMSVNSDVQLMKCMAWCPDESDTNLIACGLTSGRAILTSFSSVNRILKELVPKHTRSCNAISWNPIYTNQLAVGLDKVRGDSSTLIWDINYLQSTTLNNHLHKNNNNYISKLQQQQNNIDQPYIISQISDNSFSTSTDYTDTIYQPISEFTQSEATLALAWLPNNPSCLLVGTGSKWLKLYDIRDVNSSQSVMAHQKSVNGVCVDPFDFNRIATMSEDSHIKVWDLRNLDDPLIIVNSNCKSIQQIDWCPTRSGVLASVGKDKSSIKLWDIKAPIEFSKSPKLESTTLSTGGGGSGSNTSNNLNKRSTSNNNNSQDPINTISKPTKIHHSSDVVSSFSWHPTNECRMLTVSYSGVIDVVSLNENIPISWSPHGGICFSFGNNVLEGPTKGETLEPNILNYKNLINDGRYEKDISSKIKERAIFGYSANVEENINLANKINDENINFLWKWIQKVPIQIQNFKRESSLISTPSISTTTPGGPITPSATTKTIINNNNNNNNNKNINNNINNINNNNNNNNNNNNNNNNNNNNNNNNNNNNNEYNGIYNILIEKDISTVESSNGFVIYKSPNRNLCLSICGWGFNQSLPLENILSRLEKSGEYERAAAIAVFHLDIKRAILVVTNATYNIHPVTQTNHHGHLMRQDREFSLKLLSIALAGFDGSSTSNNNNNNNNNNNNIWKETCKSTAKSFINPYLKTCLEFLASNSDSKDIYSIIEDSRINLDDKIAFSCKYLDYQDLIHFVERNTIRVIECGNLKGVLLTGLTGRGVDLLSNYIDRTCDIQTAVLAISLVVPKFFRDKRVSKWSSIYSDLLDQWELWHERAILDIQTRISGIDQPPTPQIFAKCGFCQNSFAFESISASSIVGRNASSKPNFKAKVPFCPHCKQSLPRCCLCLLPLNCMVPTPEFKKSNTTIGSGGGSIASSGGINNSGSINNPNDSQLWSNGSEPFEDWFTWCQTCRHGGHSQHILDWFKDHSICPVTSCDCRCSQL", "length": 1119 }, "evidence": [ { "id": "F1NS24", "url": "https://omabrowser.org/oma/group/F1NS24/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q802U2-1", "protein_name": "GATOR2 complex protein MIOS", "gene_name": "mios", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSSGYKPDILWSPHHADRYVICDTELSLYRIGPSGSSETKAGALQLSEETAATLLAINSDTPFMKCVAWYPKHEPECLLAVGHTNGRVVLTSLGQSHNSKSKDLAGKEFVPKHARQCNTLAWNPVDSNWLAAGLDKHRADFSVLIWDISSKFSPEAVPAEKVRLSGDADSGLLVTKPLYELGQNDACLSLCWLPRDHQKLLLAGMHRNLAIFDLRNTSQKTFVNTKAIQGVTVDPHFQDRVASYFEGQVAIWDLRKFEKPVFTLNEQPKPLTKVAWCPTRMGLLATLTRDSNIIRLYDMQHTPMPFGDEVEPTIMERGVQPCSESIISSFAWHPSAQNRMVVVSPSRVMNDFTLFERISLAWSSTTSLMWACGRHLYECAEDSGQAAEAEKDIATKMRERAQSRYGHDTVQVWRNHVLAGGDDPQLRSLWYTLHFMKQYTENVEQKQQSNKQSLIYSGIKNIVKSSSGTTETRRCWSGSDRQTDVPRFHSEERSLALQLCGWISQGPDTDVEPFLKSLEQEGEWERAAAVALFNLDIRRAIQILNKGASSEKGDLNLNVVAMALSGYTDEKNSLWREMCSSLRLQLKKPYLCIMFAFLTSEPGAYDGVLYESRVAVRDRVAFACMFLNDAQLPRYIDKLTNEMKEAGNLEGILLTGLTKDGVDLMESYVDRTGDVQTASFCMLKGSPGEVLKDPRVQCWIENYRNLLDAWRFWHKRAEFDIHRSKLDPSSKPLAQVFVSCNFCGKSISYSCSAMPHQGRGFSQYGVSGSPTKSKVTSCPGCRKPLPRCALCLMNMGTPVSSCPGTGKADEKADLTRDKKLAQFNNWFTWCHNCRHGGHAGHMLSWFRDHSECPVSACTCKCMQLDTTGNLVPSDSV", "length": 876 }, "evidence": [ { "id": "F1NS24", "url": "https://omabrowser.org/oma/group/F1NS24/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q8VE19-1", "protein_name": "GATOR2 complex protein MIOS", "gene_name": "Mios", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSGTKPDILWAPHQVDRFVVCDSELSLYHVESAVNSELKAGSLRLSEDSAATLLSINSDTPYMKCVAWYLNYDPECLLAVGQANGRVVLTSLGQDHNSKFKDLIGKEFVPKHARQCNTLAWNPLDSNWLAAGLDKHRADFSVLIWDICSKYTPDIVPMEKVRLSAGEAETTLLVTKPLYELGQNDASLSLCWLPRDQKLLLAGMHRNLAIFDLRNTSQKMFVNTKAVQGVTVDPYFHDRVASFYEGQVAIWDLRKFEKPVLTLTEQPKPLTKVAWCPTRTGLLATLTRDSNIIRLYDMQHTPTPIGDETEPTIIERSVQPCDNYIASFAWHPTSQNRMIVVTPNRTMSDFTVFERISLAWSPITSLMWACGRHLYECAEEESDNSLEKDIATKMRLRALSRYGLDTEQVWRNHILAGNEDPQLKSLWYTLHFMKQYTEDNDQKSPGNKGSLVYAGIKSIVKSSLGMVESSRHNWSGLDKQTDIQNLNEERILALQLCGWIKKGTDVDVGPFLNSLVQEGEWERAAAVALFNLDIRRAIQILNEGASSEKGDLNLNVVAMALSGYTDEKNSLWREMCSTLRLQLNNPYLCVMFAFLTSEAGAYDGVLYENKVAVRDRVAFACKFLGDAQLNKYIEKLTNEMKEAGNLEGILLTGLTKDGVDLMESYVDRTGDVQTASYCMLQGSPLDVLKDERVQYWIENYRNLLDAWRFWHKRAEFDIHRSKLDPSSKPLAQVFVSCNFCGKSISYSCSSVPHQGRGFSQYGVSGSPTKSKVTSCPGCRKPLPRCALCLINMGTPVSSCPGGSKSDEKVDLSKDKKLAQFNNWFTWCHNCRHGGHAGHMLSWFRDHAECPVSACTCKCMQLDTTGNLVPAETVQP", "length": 875 }, "evidence": [ { "id": "F1NS24", "url": "https://omabrowser.org/oma/group/F1NS24/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9NXC5-1", "protein_name": "GATOR2 complex protein MIOS", "gene_name": "MIOS", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSGTKPDILWAPHHVDRFVVCDSELSLYHVESTVNSELKAGSLRLSEDSAATLLSINSDTPYMKCVAWYLNYDPECLLAVGQANGRVVLTSLGQDHNSKFKDLIGKEFVPKHARQCNTLAWNPLDSNWLAAGLDKHRADFSVLIWDICSKYTPDIVPMEKVKLSAGETETTLLVTKPLYELGQNDACLSLCWLPRDQKLLLAGMHRNLAIFDLRNTSQKMFVNTKAVQGVTVDPYFHDRVASFYEGQVAIWDLRKFEKPVLTLTEQPKPLTKVAWCPTRTGLLATLTRDSNIIRLYDMQHTPTPIGDETEPTIIERSVQPCDNYIASFAWHPTSQNRMIVVTPNRTMSDFTVFERISLAWSPITSLMWACGRHLYECTEEENDNSLEKDIATKMRLRALSRYGLDTEQVWRNHILAGNEDPQLKSLWYTLHFMKQYTEDMDQKSPGNKGSLVYAGIKSIVKSSLGMVESSRHNWSGLDKQSDIQNLNEERILALQLCGWIKKGTDVDVGPFLNSLVQEGEWERAAAVALFNLDIRRAIQILNEGASSEKGDLNLNVVAMALSGYTDEKNSLWREMCSTLRLQLNNPYLCVMFAFLTSETGSYDGVLYENKVAVRDRVAFACKFLSDTQLNRYIEKLTNEMKEAGNLEGILLTGLTKDGVDLMESYVDRTGDVQTASYCMLQGSPLDVLKDERVQYWIENYRNLLDAWRFWHKRAEFDIHRSKLDPSSKPLAQVFVSCNFCGKSISYSCSAVPHQGRGFSQYGVSGSPTKSKVTSCPGCRKPLPRCALCLINMGTPVSSCPGGTKSDEKVDLSKDKKLAQFNNWFTWCHNCRHGGHAGHMLSWFRDHAECPVSACTCKCMQLDTTGNLVPAETVQP", "length": 875 }, "evidence": [ { "id": "F1NS24", "url": "https://omabrowser.org/oma/group/F1NS24/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VQ89-1", "protein_name": "GATOR2 complex protein Mio", "gene_name": "mio", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSGNTHGLSWFPHFPDKFVSWGQEIHLYEVRRKDDHSQKSRLPYISVNYLANESRYQYARCVAASYHSDQPIIAVGLADGKVGICNFRDTYDSSWEYTPRQQRMCTCLAWNELDANILAIGHDRHRNDTCITIWDIERGVPKETANFFGVGESANSICWDRNHRTVIAGMSQKMIKLFDLRQSNATCQSIQTKTVQGLSVSPNGNYLCSYVDSVITLWDPRNIKSPLRQIQSSKNHLQIAWCPTRTSLLSSLQRDSSYITLYDIRSVDTDNSGEIYHVKRQISPFPARYQHSGKFSFVNCLSWHSRDFERALLLADALNILDFRLPATLHTAHSNRRKLPLLMQRPLYTPASPTSTAATPTQQQPTSSCSTNSGSSLDFSTPGGSPFNVDLLKPELFELDLVDETRQRALEDYGIKPDNKRFGELHLTPYLRNVWSTLNNVYSEDRLTGLKATLGINLGHTSEALMASSRIESQVLQWPEGINNSNKLICYRSEQRDLALQLCGWAFEQELDRFIDQLYANKEYSRAAMICVFHLKIFHACNILSSAADNMRDPSMYRITVIALSSFNADRCSSTWRNQRSSANMQIHDPHLRAVFSFLTMEKDNFDAVLKEEGVSLSDRMAFACKYLSETKLADYVAQQIQAAIDGGDLNGLLLTGESQDGIDILQSYMDTSFDVQTVALVAINYFRQELFEDKRIQYWIASYLDHLNSWGLWEKRAELDIKIESIRPSSRSSRTVFLSCNFCGKSVSNALLDEPRPRSTTTSTNRLSSCPSCRKPLPRCSLCLMHMGTMVNMSNGETPTTTPDVPGWQTKPFSKWFSWCQTCRHGGHTEHIMQWFKQNSECPVSSCNCRCFDMDGTKPNTLRDIS", "length": 867 }, "evidence": [ { "id": "F1NS24", "url": "https://omabrowser.org/oma/group/F1NS24/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "F1NS24", "url": "https://www.uniprot.org/uniprotkb/F1NS24" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "lysosomal membrane", "id": "GO:0005765", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005765", "evidence": [ { "database": "UniProtKB", "id": "F1NS24", "url": "https://www.uniprot.org/uniprotkb/F1NS24" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "F1NS24", "url": "https://www.uniprot.org/uniprotkb/F1NS24" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1NS24", "url": "https://www.uniprot.org/uniprotkb/F1NS24" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F1NS24", "url": "https://www.uniprot.org/uniprotkb/F1NS24" } ], "pmid": "" }, { "name": "GATOR2 complex", "id": "GO:0061700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061700", "evidence": [ { "database": "UniProtKB", "id": "F1NS24", "url": "https://www.uniprot.org/uniprotkb/F1NS24" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "positive regulation of TORC1 signaling", "id": "GO:1904263", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904263", "evidence": [ { "database": "UniProtKB", "id": "F1NS24", "url": "https://www.uniprot.org/uniprotkb/F1NS24" } ], "pmid": "" }, { "name": "central nervous system myelin formation", "id": "GO:0032289", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032289", "evidence": [ { "database": "UniProtKB", "id": "F1NS24", "url": "https://www.uniprot.org/uniprotkb/F1NS24" } ], "pmid": "" }, { "name": "cellular response to amino acid starvation", "id": "GO:0034198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034198", "evidence": [ { "database": "UniProtKB", "id": "F1NS24", "url": "https://www.uniprot.org/uniprotkb/F1NS24" } ], "pmid": "" }, { "name": "protein-containing complex localization", "id": "GO:0031503", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031503", "evidence": [ { "database": "UniProtKB", "id": "F1NS24", "url": "https://www.uniprot.org/uniprotkb/F1NS24" } ], "pmid": "" }, { "name": "oligodendrocyte progenitor proliferation", "id": "GO:0070444", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070444", "evidence": [ { "database": "UniProtKB", "id": "F1NS24", "url": "https://www.uniprot.org/uniprotkb/F1NS24" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 216, "end_pos": 218, "annotation": "n_glycosylation_sequon" }, { "start_pos": 345, "end_pos": 347, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1NS24-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 877, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1NS24-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1NS24" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1NS24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NS24" }, { "id": "PF17034", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17034" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "GATOR2 complex protein MIO zinc-ribbon like", "eco_id": "ECO_0000259", "start_pos": 739, "end_pos": 861, "start_aa": "Cys", "end_aa": "Met", "glycosite_overlap": "" }, { "evidence": [ { "id": "F1NS24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NS24" }, { "id": "PF21719", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21719" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "MIOS-like alpha-solenoid", "eco_id": "ECO_0000259", "start_pos": 395, "end_pos": 625, "start_aa": "Met", "end_aa": "Phe", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 216, "end_pos": 218 }, { "start_pos": 345, "end_pos": 347 } ] 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"publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1NUR0-1", "uniprot_ac": "F1NUR0", "uniprot_id": "F1NUR0_CHICK", "mass": { "chemical_mass": 48411.0, "monoisotopic_mass": 48411.0 }, "refseq": { "ac": "XP_004938365", "name": "ADP-ribosylation factor-like protein 13B isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004938365" }, "gene_names": [ { "name": "ARL13B", "type": "recommended", "evidence": [ { "id": "F1NUR0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NUR0" } ] }, { "name": "ARL13B", "type": "synonym", "evidence": [ { "id": "XP_004938365", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004938365" } ] } ], "protein_names": [ { "name": "ADP-ribosylation factor-like protein 13B isoform X1", "type": "synonym", "evidence": [ { "id": "XP_004938365", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004938365" } ] }, { "name": "ARF like GTPase 13B", "type": "synonym", "evidence": [ { "id": "F1NUR0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NUR0/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004938365", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004938365" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NUR0", "url": "https://www.uniprot.org/uniprotkb/F1NUR0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ARL13B", "url": "https://www.uniprot.org/uniprotkb/F1NUR0", "locus": { "chromosome": "1", "start_pos": 89940880, "end_pos": 89891671, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010006273", "url": "https://www.ensembl.org/id/ENSGALG00010006273" } ] } } ], "crossref": [ { "id": "F1NUR0", "url": "https://alphafold.ebi.ac.uk/entry/F1NUR0", "database": "AlphaFoldDB", 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"InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:418431", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418431", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QKMEHEQ", "url": "https://omabrowser.org/oma/group/QKMEHEQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XKU5", "url": "https://www.orthodb.org/?gene=A0A8V0XKU5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XS60", "url": "https://www.orthodb.org/?gene=A0A8V0XS60", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NUR0", "url": "https://www.orthodb.org/?gene=F1NUR0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46090", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46090", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46090:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46090:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00025", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00025", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-5624958", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5624958", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9013406", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013406", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9646399", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9646399", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_004938365", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004938365", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0XKU5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XKU5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XKU5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XKU5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XS60", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XS60", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XS60-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XS60-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NUR0", "url": "https://www.uniprot.org/uniprotkb/F1NUR0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NUR0-1", "url": "https://www.uniprot.org/uniprotkb/F1NUR0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MFNLMANCCTWLKRWQEPVRKVTLIMVGLDNAGKTATVRGIQGESPEDVAPTVGFSKIDLKQGRFEVTIFDLGGGKRIRNIWRNYYAESYGVIFVVDSSDIERMEETKEAMTEVLNSPKISGKPVLVLANKQDREGALSEADVIETLSLEKLVNEHKCLCQIEPCSAVMGYGKKIDKSIKKGLYWLLHIIAKDFDALNERIQRDTTEQKAYEEQKKRERAERVRRIREEREREEGRSVHDEEDPEPGNSENPFQPIAAVISENEKQIEKEKKWQRLEAEKATVVSKSQTEQEQMDAQQLSTNSSQKTNDSRLETCNSTTAQHFQHEENEQQTSESLDSDNSKKKNKKTKLKRGHRVEPINGDDTVAPNPTPPPSLPPVGWGTPKLNRLRKLEPLGETHHTDFYGKPLPPLTVRQRPNSDTHDVIA", "length": 425, "header": "tr|F1NUR0-1|F1NUR0_CHICK Isoform 1 of ARF like GTPase 13B OS=Gallus gallus OX=9031 GN=ARL13B PE=4 SV=2 CANONICAL=F1NUR0-1" }, "isoforms": [ { "isoform_ac": "A0A8V0XKU5-1", "url": "https://www.uniprot.org/uniprotkb/F1NUR0/entry#A0A8V0XKU5-1", "sequence": { "sequence": "MFNLMANCCTWLKRWQEPVRKVTLIMVGLDNAGKTATVRGIQGESPEDVAPTVGFSKIDLKQGRFEVTIFDLGGGKRIRNIWRNYYAESYGVIFVVDSSDIERMEETKEAMTEVLNSPKISGKPVLVLANKQDREGALSEADVIETLSLEKLVNEHKCLCQIEPCSAVMGYGKKIDKSIKKGLYWLLHIIAKDFDALNERIQRDTTEQKAYEEQKKRERAERVRRIREEREREEGRSVHDEEDPEPGNSENPFQPIAAVISENEKQIEKEKKWQRLEAEKATVVSKSQTEQEQMDAQQLSTNSSQKTNDSRLETCNSTTAQHFQHEENEQQTSESLDSDNSKKKNKKTKLKRGHRVEPINGDDTVAPNPTPPPSLPPVGWGTPKLNRLRKLEPLGETHHTGM", "length": 402, "header": "tr|A0A8V0XKU5-1|A0A8V0XKU5_CHICK Computationally mapped isoform of ARF like GTPase 13B OS=Gallus gallus OX=9031 GN=ARL13B PE=4 SV=1 CANONICAL=F1NUR0-1" }, "locus": { "chromosome": "1", "start_pos": 89934235, "end_pos": 89896223, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010014959.1", "url": "https://www.ensembl.org/id/ENSGALT00010014959.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010008807.1", "url": "https://www.ensembl.org/id/ENSGALP00010008807.1" } ] } }, { "isoform_ac": "A0A8V0XS60-1", "url": 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"https://www.ensembl.org/id/ENSGALP00010008804.1" } ] } }, { "isoform_ac": "F1NUR0-1", "url": "https://www.uniprot.org/uniprotkb/F1NUR0/entry#F1NUR0-1", "sequence": { "sequence": "MFNLMANCCTWLKRWQEPVRKVTLIMVGLDNAGKTATVRGIQGESPEDVAPTVGFSKIDLKQGRFEVTIFDLGGGKRIRNIWRNYYAESYGVIFVVDSSDIERMEETKEAMTEVLNSPKISGKPVLVLANKQDREGALSEADVIETLSLEKLVNEHKCLCQIEPCSAVMGYGKKIDKSIKKGLYWLLHIIAKDFDALNERIQRDTTEQKAYEEQKKRERAERVRRIREEREREEGRSVHDEEDPEPGNSENPFQPIAAVISENEKQIEKEKKWQRLEAEKATVVSKSQTEQEQMDAQQLSTNSSQKTNDSRLETCNSTTAQHFQHEENEQQTSESLDSDNSKKKNKKTKLKRGHRVEPINGDDTVAPNPTPPPSLPPVGWGTPKLNRLRKLEPLGETHHTDFYGKPLPPLTVRQRPNSDTHDVIA", "length": 425, "header": "tr|F1NUR0-1|F1NUR0_CHICK Isoform 1 of ARF like GTPase 13B OS=Gallus gallus OX=9031 GN=ARL13B PE=4 SV=2 CANONICAL=F1NUR0-1" }, "locus": { "chromosome": "1", "start_pos": 89938878, "end_pos": 89896223, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010014953.1", "url": "https://www.ensembl.org/id/ENSGALT00010014953.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010008802.1", "url": "https://www.ensembl.org/id/ENSGALP00010008802.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 370, "start_aa": "Thr", "end_pos": 370, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr370", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 52, "start_aa": "Thr", "end_pos": 52, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr52", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:418431", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418431", "resource": "KEGG Pathway" }, { "id": "R-GGA-5624958", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5624958", "resource": "Reactome", "description": "ARL13B-mediated ciliary trafficking of INPP5E" }, { "id": "R-GGA-9013406", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013406", "resource": "Reactome", "description": "RHOQ GTPase cycle" }, { "id": "R-GGA-9646399", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9646399", "resource": "Reactome", "description": "Aggrephagy" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A480SX75-1", "protein_name": "ADP ribosylation factor like GTPase 13B", "gene_name": "ARL13B", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MFSLMANCCGWFKRWREPVRKVTLVMVGLDNAGKTATAKGIQGEYPEDVAPTVGFSKIDLRQGKFEVTIFDLGGGKRIRGIWKNYYAESYGVIFVVDSSDEERMEETKETMSEVLRHPRISGKPILVLANKQDKEGALGEADVIECLSLEKLVNEHKCLCQIEPCSAVLGYGKKIDKSIKKGLYWLLHIIARDFDALNERIQKDTTEQRALEEQEKRERAERVRKLREEREQREQEQAEHHGTSGLAELDPEPIIVNPFQPIASVIIENEKKLEKEKKRQNMEKDSDGSLLKHEMEHEEIETQSQISDSSQKNDEFGIVENYKEALTHQLENEDETDHRSSEPDNSKKKTKKLRMKRSHRVEPVNTDDSAPKSPTPPPPPPPVGWGTPKVTRLPKLEPLGETRHNDFYGKPLPPLAVRQRPNSDAHDVIS", "length": 430 }, "evidence": [ { "id": "F1NUR0", "url": "https://omabrowser.org/oma/group/F1NUR0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "M0RDU9-1", "protein_name": "ADP-ribosylation factor like GTPase 13B", "gene_name": "Arl13b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFNLMANCCNLFKRWREPVRKVTLVMVGLDNAGKTATAKGIQGEHPEDVAPTVGFSKIDLRQGKFEVTIFDLGGGKRIRGIWKNYYAESYGVIFVVDSSDEDRMEETKETMSEVLRHPRISGKPILVLANKQDKEGALGEADVIECLSLEKLVNEHKCLCQIEPCSAVLGYGKKIDKSIKKGLYWLLHIIAKDFDALSERIQKDTTEQRALEEQEKCERAERVRKLREERSFPPPPTNREQEQTELDGTSGLAEMDSGPVLTNPFQPIAAVIIENEKKQEKEKKKKTAEKDSDVGHPEHKGEQEGAESQNEAGGCLRNPHRDVVNSYKEALSQQLDNEDELDQRVSEPGDNSKKKTKKLRMKRSHRVEPVNTDESAPKSPTPPPPPPPVGWGTPKVTRLPKLEPLGETRHNDFYGKPLPPLAVRQRPNGDAQDMIS", "length": 436 }, "evidence": [ { "id": "F1NUR0", "url": "https://omabrowser.org/oma/group/F1NUR0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q3SXY8-1", "protein_name": "ADP-ribosylation factor-like protein 13B", "gene_name": "ARL13B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MFSLMASCCGWFKRWREPVRKVTLLMVGLDNAGKTATAKGIQGEYPEDVAPTVGFSKINLRQGKFEVTIFDLGGGIRIRGIWKNYYAESYGVIFVVDSSDEERMEETKEAMSEMLRHPRISGKPILVLANKQDKEGALGEADVIECLSLEKLVNEHKCLCQIEPCSAISGYGKKIDKSIKKGLYWLLHVIARDFDALNERIQKETTEQRALEEQEKQERAERVRKLREERKQNEQEQAELDGTSGLAELDPEPTNPFQPIASVIIENEGKLEREKKNQKMEKDSDGCHLKHKMEHEQIETQGQVNHNGQKNNEFGLVENYKEALTQQLKNEDETDRPSLESANGKKKTKKLRMKRNHRVEPLNIDDCAPESPTPPPPPPPVGWGTPKVTRLPKLEPLGETHHNDFYRKPLPPLAVPQRPNSDAHDVIS", "length": 428 }, "evidence": [ { "id": "F1NUR0", "url": "https://omabrowser.org/oma/group/F1NUR0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q640N2-1", "protein_name": "ADP-ribosylation factor-like protein 13B", "gene_name": "Arl13b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSLMANCCNLFKRWREPVRKVTLVMVGLDNAGKTATAKGIQGEHPEDVAPTVGFSKIDLRQGKFQVTIFDLGGGKRIRGIWKNYYAESYGVIFVVDSSDEERMEETKETMSEVLRHPRISGKPILVLANKQDKEGALGEADVIECLSLEKLVNEHKCLCQIEPCSAVLGYGKKIDKSIKKGLYWLLHIIAKDFDALSERIQKDTTEQRALEEQEKRERAERVRKLREEREREQTELDGTSGLAEIDSGPVLANPFQPIAAVIIENEKKQEKEKKKQTVEKDSDVGLLEHKVEPEQAAPQSEADCCLQNPDERVVDSYREALSQQLDSEDEQDQRGSESGENSKKKTKKLRMKRSHRVEPVNTDESTPKSPTPPQPPPPVGWGTPKVTRLPKLEPLGETRHNDFYGKPLPPLAVRQRPNGDAQDTIS", "length": 427 }, "evidence": [ { "id": "F1NUR0", "url": "https://omabrowser.org/oma/group/F1NUR0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "GTPase activity", "id": "GO:0003924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003924", "evidence": [ { "database": "UniProtKB", "id": "F1NUR0", "url": "https://www.uniprot.org/uniprotkb/F1NUR0" } ], "pmid": "" }, { "name": "GTP binding", "id": "GO:0005525", "url": 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"https://www.ebi.ac.uk/QuickGO/term/GO:0031514", "evidence": [ { "database": "UniProtKB", "id": "F1NUR0", "url": "https://www.uniprot.org/uniprotkb/F1NUR0" } ], "pmid": "" }, { "name": "microtubule cytoskeleton", "id": "GO:0015630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015630", "evidence": [ { "database": "UniProtKB", "id": "F1NUR0", "url": "https://www.uniprot.org/uniprotkb/F1NUR0" } ], "pmid": "" }, { "name": "intercellular bridge", "id": "GO:0045171", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045171", "evidence": [ { "database": "UniProtKB", "id": "F1NUR0", "url": "https://www.uniprot.org/uniprotkb/F1NUR0" } ], "pmid": "" }, { "name": "axoneme", "id": "GO:0005930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005930", "evidence": [ { "database": "UniProtKB", "id": "F1NUR0", "url": "https://www.uniprot.org/uniprotkb/F1NUR0" } ], "pmid": "" }, { "name": "non-motile cilium", "id": "GO:0097730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097730", "evidence": [ { 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316, "end_pos": 318 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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}, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1NH93-1", "uniprot_ac": "F1NH93", "uniprot_id": "F1NH93_CHICK", "mass": { "chemical_mass": 13374.0, "monoisotopic_mass": 13374.0 }, "refseq": { "ac": "XP_428540", "name": "40S ribosomal protein S20", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_428540" }, "gene_names": [ { "name": "RPS20", "type": "recommended", "evidence": [ { "id": "F1NH93", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NH93" } ] }, { "name": "RPS20", "type": "synonym", "evidence": [ { "id": "XP_428540", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_428540" } ] } ], "protein_names": [ { "name": "Small ribosomal subunit protein uS10", "type": "recommended", "evidence": [ { "id": "F1NH93", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NH93/entry#names_and_taxonomy" } ] }, { "name": "40S ribosomal protein S20", "type": "synonym", "evidence": [ { "id": "XP_428540", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_428540" }, { "id": "F1NH93", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NH93/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052533.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Dec 16, 2011 this sequence version replaced XP_428540.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_428540", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_428540" } ] }, { "annotation": "Component of the small ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.", "evidence": [ { "database": "UniProtKB", "id": "F1NH93", "url": "https://www.uniprot.org/uniprotkb/F1NH93#function" }, { "database": "UniProtKB", "id": "ARBA00045746", "url": "https://www.uniprot.org/uniprotkb/ARBA00045746#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NH93", "url": "https://www.uniprot.org/uniprotkb/F1NH93" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RPS20", "url": "https://www.uniprot.org/uniprotkb/F1NH93", "locus": { "chromosome": "2", "start_pos": 110903280, "end_pos": 110906135, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010004081", "url": "https://www.ensembl.org/id/ENSGALG00010004081" } ] } } ], "crossref": [ { "id": "F1NH93", "url": "https://alphafold.ebi.ac.uk/entry/F1NH93", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000014432", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000014432", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "430990", "url": "https://www.ncbi.nlm.nih.gov/gene/430990", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "8Q7Z", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=8Q7Z&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "8Q87", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=8Q87&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "IPR001848", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001848", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005729", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005729", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018268", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018268", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027486", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027486", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036838", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036838", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:430990", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:430990", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WCEYRRR", "url": "https://omabrowser.org/oma/group/WCEYRRR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XLC8", "url": "https://www.orthodb.org/?gene=A0A8V0XLC8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NH93", "url": "https://www.orthodb.org/?gene=F1NH93", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11700", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11700", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "pdb_00008q7z", "url": "https://www.rcsb.org/structure/pdb_00008q7z", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00008q87", "url": "https://www.rcsb.org/structure/pdb_00008q87", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "8Q7Z", "url": "https://www.rcsb.org/structure/8Q7Z", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "8Q87", "url": "https://www.rcsb.org/structure/8Q87", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "PF00338", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00338", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-1799339", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1799339", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-72649", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-72649", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-72695", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-72695", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-72702", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-72702", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-72706", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-72706", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-975956", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-975956", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-975957", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-975957", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9954714", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9954714", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9954716", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9954716", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_428540", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_428540", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0XLC8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XLC8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XLC8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XLC8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NH93", "url": "https://www.uniprot.org/uniprotkb/F1NH93", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NH93-1", "url": "https://www.uniprot.org/uniprotkb/F1NH93-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAFKDTGKAPVEQEVAIHRIRITLTSRNVKSLEKVCADLIRGAKEKNLKVKGPVRMPTKTLRITTRKTPCGEGSKTWDRFQMRIHKRLIDLHSPSEIVKQITSISIEPGVEVEVTIADA", "length": 119, "header": "tr|F1NH93-1|F1NH93_CHICK Isoform 1 of Small ribosomal subunit protein uS10 OS=Gallus gallus OX=9031 GN=RPS20 PE=1 SV=3 CANONICAL=F1NH93-1" }, "isoforms": [ { "isoform_ac": "A0A8V0XLC8-1", "url": "https://www.uniprot.org/uniprotkb/F1NH93/entry#A0A8V0XLC8-1", "sequence": { "sequence": "MAFKDTGKAPVEQEVAIHRIRITLTSRNVKSLEKDSANHYQEDTLW", "length": 46, "header": "tr|A0A8V0XLC8-1|A0A8V0XLC8_CHICK Computationally mapped isoform of Ribosomal protein S20 OS=Gallus gallus OX=9031 GN=RPS20 PE=1 SV=1 CANONICAL=F1NH93-1" }, "locus": { "chromosome": "2", "start_pos": 110905840, "end_pos": 110903471, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010009484.1", "url": "https://www.ensembl.org/id/ENSGALT00010009484.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010005592.1", "url": "https://www.ensembl.org/id/ENSGALP00010005592.1" } ] } }, { "isoform_ac": "F1NH93-1", "url": "https://www.uniprot.org/uniprotkb/F1NH93/entry#F1NH93-1", "sequence": { "sequence": "MAFKDTGKAPVEQEVAIHRIRITLTSRNVKSLEKVCADLIRGAKEKNLKVKGPVRMPTKTLRITTRKTPCGEGSKTWDRFQMRIHKRLIDLHSPSEIVKQITSISIEPGVEVEVTIADA", "length": 119, "header": "tr|F1NH93-1|F1NH93_CHICK Isoform 1 of Small ribosomal subunit protein uS10 OS=Gallus gallus OX=9031 GN=RPS20 PE=1 SV=3 CANONICAL=F1NH93-1" }, "locus": { "chromosome": "2", "start_pos": 110905840, "end_pos": 110903326, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010009482.1", "url": "https://www.ensembl.org/id/ENSGALT00010009482.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010005591.1", "url": "https://www.ensembl.org/id/ENSGALP00010005591.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Cryo-EM structure of the inactive ribosome complex accumulated in chick embryo cells in cold-stress conditions.", "journal": "FEBS Lett.", "date": "2024", "authors": "Nurullina Liliia, Terrosu Salvatore, Myasnikov Alexander G, Jenner Lasse Bohl, Yusupov Marat", "evidence": [ { "database": "UniProtKB", "id": "F1NH93", "url": "https://www.uniprot.org/uniprotkb/F1NH93" } ], "reference": [ { "type": "PubMed", "id": "38395592", "url": "https://glygen.org/publication/PubMed/38395592" } ] } ], "pathway": [ { "id": "gga:430990", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:430990", "resource": "KEGG Pathway" }, { "id": "R-GGA-1799339", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1799339", "resource": "Reactome", "description": "SRP-dependent cotranslational protein targeting to membrane" }, { "id": "R-GGA-72649", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-72649", "resource": "Reactome", "description": "Translation initiation complex formation" }, { "id": "R-GGA-72695", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-72695", "resource": "Reactome", "description": "Formation of the ternary complex, and subsequently, the 43S complex" }, { "id": "R-GGA-72702", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-72702", "resource": "Reactome", "description": "Ribosomal scanning and start codon recognition" }, { "id": "R-GGA-72706", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-72706", "resource": "Reactome", "description": "GTP hydrolysis and joining of the 60S ribosomal subunit" }, { "id": "R-GGA-975956", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-975956", "resource": "Reactome", "description": "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" }, { "id": "R-GGA-975957", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-975957", "resource": "Reactome", "description": "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" }, { "id": "R-GGA-9954714", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9954714", "resource": "Reactome", "description": "PELO:HBS1L and ABCE1 dissociate a ribosome on a non-stop mRNA" }, { "id": "R-GGA-9954716", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9954716", "resource": "Reactome", "description": "ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A4X1SWA8-1", "protein_name": "Small ribosomal subunit protein uS10", "gene_name": "RPS20", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAFKDTGKTPVEPEVAIHRIRITLTSRNVKSLEKVCADLIRGAKEKNLKVKGPVRMPTKTLRITTRKTPCGEGSKTWDRFQMRIHKRLIDLHSPSEIVKQITSISIEPGVEVEVTIADA", "length": 119 }, "evidence": [ { "id": "F1NH93", "url": "https://omabrowser.org/oma/group/F1NH93/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P60866-1", "protein_name": "Small ribosomal subunit protein uS10", "gene_name": "RPS20", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAFKDTGKTPVEPEVAIHRIRITLTSRNVKSLEKVCADLIRGAKEKNLKVKGPVRMPTKTLRITTRKTPCGEGSKTWDRFQMRIHKRLIDLHSPSEIVKQITSISIEPGVEVEVTIADA", "length": 119 }, "evidence": [ { "id": "F1NH93", "url": "https://omabrowser.org/oma/group/F1NH93/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P60867-1", "protein_name": "Small ribosomal subunit protein uS10", "gene_name": "Rps20", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAFKDTGKTPVEPEVAIHRIRITLTSRNVKSLEKVCADLIRGAKEKNLKVKGPVRMPTKTLRITTRKTPCGEGSKTWDRFQMRIHKRLIDLHSPSEIVKQITSISIEPGVEVEVTIADA", "length": 119 }, "evidence": [ { "id": "F1NH93", "url": "https://omabrowser.org/oma/group/F1NH93/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P60868-1", "protein_name": "Small ribosomal subunit protein uS10", "gene_name": "Rps20", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAFKDTGKTPVEPEVAIHRIRITLTSRNVKSLEKVCADLIRGAKEKNLKVKGPVRMPTKTLRITTRKTPCGEGSKTWDRFQMRIHKRLIDLHSPSEIVKQITSISIEPGVEVEVTIADA", "length": 119 }, "evidence": [ { "id": "F1NH93", "url": "https://omabrowser.org/oma/group/F1NH93/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q3ZBH8-1", "protein_name": "Small ribosomal subunit protein uS10", "gene_name": "RPS20", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAFKDTGKTPVEPEVAIHRIRITLTSRNVKSLEKVCADLIRGAKEKNLKVKGPVRMPTKTLRITTRKTPCGEGSKTWDRFQMRIHKRLIDLHSPSEIVKQITSISIEPGVEVEVTIADA", "length": 119 }, "evidence": [ { "id": "F1NH93", "url": "https://omabrowser.org/oma/group/F1NH93/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "F1NH93", "url": "https://www.uniprot.org/uniprotkb/F1NH93" } ], "pmid": "" }, { "name": "MDM2/MDM4 family protein binding", "id": "GO:0097371", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097371", "evidence": [ { "database": "UniProtKB", "id": "F1NH93", "url": "https://www.uniprot.org/uniprotkb/F1NH93" } ], "pmid": "" }, { "name": "ubiquitin ligase inhibitor activity", "id": "GO:1990948", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990948", "evidence": [ { "database": "UniProtKB", "id": "F1NH93", "url": "https://www.uniprot.org/uniprotkb/F1NH93" } ], "pmid": "" }, { "name": "structural constituent of ribosome", "id": "GO:0003735", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003735", "evidence": [ { "database": "UniProtKB", "id": "F1NH93", "url": "https://www.uniprot.org/uniprotkb/F1NH93" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "F1NH93", "url": "https://www.uniprot.org/uniprotkb/F1NH93" } ], "pmid": "" }, { "name": "synapse", "id": "GO:0045202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045202", "evidence": [ { "database": "UniProtKB", "id": "F1NH93", "url": "https://www.uniprot.org/uniprotkb/F1NH93" } ], "pmid": "" }, { "name": "cytosolic small ribosomal subunit", "id": "GO:0022627", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022627", "evidence": [ { "database": "UniProtKB", "id": "F1NH93", "url": "https://www.uniprot.org/uniprotkb/F1NH93" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "translation", "id": "GO:0006412", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006412", "evidence": [ { "database": "UniProtKB", "id": "F1NH93", "url": "https://www.uniprot.org/uniprotkb/F1NH93" } ], "pmid": "" }, { "name": "positive regulation of signal transduction by p53 class mediator", "id": "GO:1901798", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901798", "evidence": [ { "database": "UniProtKB", "id": "F1NH93", "url": "https://www.uniprot.org/uniprotkb/F1NH93" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1NH93-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 119, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1NH93-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1NH93" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1NH93", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NH93" }, { "id": "SM01403", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM01403" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Small ribosomal subunit protein uS10", "eco_id": "ECO_0000259", "start_pos": 21, "end_pos": 115, "start_aa": "Arg", "end_aa": "Thr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "F1P0K0-1", "uniprot_ac": "F1P0K0", "uniprot_id": "F1P0K0_CHICK", "mass": { "chemical_mass": 95760.0, "monoisotopic_mass": 95760.0 }, "refseq": { "ac": "NP_001292495", "name": "M-phase phosphoprotein 8", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001292495" }, "gene_names": [ { "name": "MPHOSPH8", "type": "recommended", "evidence": [ { "id": "F1P0K0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P0K0" } ] }, { "name": "MPHOSPH8", "type": "synonym", "evidence": [ { "id": "NP_001292495", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001292495" } ] } ], "protein_names": [ { "name": "M-phase phosphoprotein 8", "type": "synonym", "evidence": [ { "id": "NP_001292495", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001292495" }, { "id": "F1P0K0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P0K0/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: ERR2286007.63947.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA103992290, SAMEA103992323 [ECO:0006172] ##Evidence-Data-END## INFERRED REFSEQ: This record is predicted by genome sequence analysis and is not yet supported by experimental evidence. The reference sequence was derived from JAENSK010000027.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001292495", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001292495" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1P0K0", "url": "https://www.uniprot.org/uniprotkb/F1P0K0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MPHOSPH8", "url": "https://www.uniprot.org/uniprotkb/F1P0K0", "locus": { "chromosome": "1", "start_pos": 179094619, "end_pos": 179114152, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010005313", "url": "https://www.ensembl.org/id/ENSGALG00010005313" } ] } } ], "crossref": [ { "id": "F1P0K0", "url": "https://alphafold.ebi.ac.uk/entry/F1P0K0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000017145", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000017145", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd18633", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18633", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "418957", "url": "https://www.ncbi.nlm.nih.gov/gene/418957", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000953", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000953", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016197", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016197", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023779", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023779", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023780", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023780", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036770", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036770", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050889", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050889", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:418957", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418957", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PNRACHP", "url": "https://omabrowser.org/oma/group/PNRACHP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XMU3", "url": "https://www.orthodb.org/?gene=A0A8V0XMU3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XQK4", "url": "https://www.orthodb.org/?gene=A0A8V0XQK4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1P0K0", "url": "https://www.orthodb.org/?gene=F1P0K0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24166", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24166", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24166:SF47", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24166:SF47", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00023", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00023", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00385", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00385", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12796", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12796", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-9764725", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9764725", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9843970", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9843970", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001292495", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001292495", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0XMU3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMU3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XMU3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMU3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XQK4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQK4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XQK4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQK4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1P0K0", "url": "https://www.uniprot.org/uniprotkb/F1P0K0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1P0K0-1", "url": "https://www.uniprot.org/uniprotkb/F1P0K0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAAGSGAEAAAARLEGAGEEEETAAAGDGENEVVDGGGAGGAAGAAAAGGESEEEEDVFEVEKILDVKTEGGVILYKVRWKGYTSDDDTWEPEVHLEDCKEVLLEFRKKLVDTKPKPAKKDLQKLSLNDDLFEAESDNDGQSEIKEDVSPKKKKKKSKEGEDRSADDLKKKKSKSAKVKEKPRTECESSSGTLGLDSKPKKRTSETKEDSKDPKKQRKEDSKEVKKKKGEVKDVKIKTKEDSKESKKSRKEKQGDAQFDTETSALDDALLQEIDNENPGLYSENKEEEQQVKCEKERVEEETAEKDSIADRQLDGSASNEDDSVEVKAKRKKKKNQKVEDYKEEGRKVEIKDIYLEKKSMLKKQKSQEKVKVVAAELEKVSAAPVSAQKALKVSAEERGRKAMESAEEEKEIKKSEMKEKSVKKESEKEEKIRKEQKVVKSYKDIKSALDMFNVASEEKKEYSENNCKREEPSLEYKFIEELKLKDSKVHKERRIKDEAETWNYVAAGGGREVVDVCHMENSDGKQQVLSLGMDMQLEWLTLEDFQKHLDGEDENHISAEPISSTLLRDAVKSGDYMTVKMALSSSEEYNLDQEDSSGMTLVMLAAAGGHDDLLRVLIRKGAKVNGRQKNGTTALIHAAEKNFLTTVAILLEAGAYVNMQQSSGETALMKACKRGNSDIVRLMIESGADCNILSKHQNSALHFAKQCNNVLVYEQLKSHLETLSRVAEDTIRDYFEARLVLLEPVFPIACHRLCEGPDFSTDFNYKPPQNVPEGSGILLFIFHANFFGKEVVARLCGPCSVQAVVLNDKFQLPVFLDSHFIYSFSPTAGLNKLFIRLAEAPTAKVKLLIGAYRVQLQ", "length": 858, "header": "tr|F1P0K0-1|F1P0K0_CHICK Isoform 1 of M-phase phosphoprotein 8 OS=Gallus gallus OX=9031 GN=MPHOSPH8 PE=4 SV=4 CANONICAL=F1P0K0-1" }, "isoforms": [ { "isoform_ac": "A0A8V0XMU3-1", "url": "https://www.uniprot.org/uniprotkb/F1P0K0/entry#A0A8V0XMU3-1", "sequence": { "sequence": "MAAAGSGAEAAAARLEGAGEEEETAAAGDGENEVVDGGGAGGAAGAAAAGGESEEEEDVFEVEKILDVKTEGGVILYKVRWKGYTSDDDTWEPEVHLEDCKEVLLEFRKKLVDTKPKPAKKDLQKLSLNDDLFEAESDNDGQSEIKEDVSPKKKKKKSKEGEDRSADDLKKKKSKSAKVKEKPRTECESSSGTLGLDSKPKKRTSETKEDSKDPKKQRKEDSKEVKKKKGEVKDVKIKTKEDSKESKKSRKEKQGDAQFDTETSALDDALLQEIDNENPGLYSENKEEEQQVKCEKERVEEETAEKDSIADRQLDGSASNEDDSVEVKAKRKKKKNQKVEDYKEEGRKVEIKDIYLEKKSMLKKQKSQEKVKVVAAELEKVSAAPVSAQKALKVSAEERGRKAMESAEEEKEIKKSEMKEKSVKKESEKEEKIRKEQKVVKSYKDIKSALDMFNVASEEKKEYSENNCKREEPSLEYKFIEELKLKDSKVHKERRIKDEAETWNYVAAGGGREVVDVCHMENSDGKQQVLSLGMDMQLEWLTLEDFQKHLDGEDENHISAEPISSTLLRDAVKSGDYMTVKMALSSSEEYNLDQEDSSGMTLVMLAAAGGHDDLLRVLIRKGAKVNGRQKNGTTALIHAAEKNFLTTVAILLEAGAYVNMQQSSGETALMKACKRGNSDIVRLMIESGADCNILSKHQNSALHFAKQCNNVLVYEQLKSHLETLSRVAEDTIRDYFEARLVLLEPVFPIACHRLCEGPDFSTDFNYKPPQNVPEGSGILLFIFHANFFGKEVVARLCGPCSVQAVVLNDKFQLPVFLVKLLIGAYRVQLQ", "length": 830, "header": "tr|A0A8V0XMU3-1|A0A8V0XMU3_CHICK Computationally mapped isoform of M-phase phosphoprotein 8 OS=Gallus gallus OX=9031 GN=MPHOSPH8 PE=4 SV=1 CANONICAL=F1P0K0-1" }, "locus": { "chromosome": "1", "start_pos": 179113953, "end_pos": 179095920, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010012598.1", "url": "https://www.ensembl.org/id/ENSGALT00010012598.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010007162.1", "url": "https://www.ensembl.org/id/ENSGALP00010007162.1" } ] } }, { "isoform_ac": "A0A8V0XQK4-1", "url": "https://www.uniprot.org/uniprotkb/F1P0K0/entry#A0A8V0XQK4-1", "sequence": { "sequence": "MHLCHSVKGVILYKVRWKGYTSDDDTWEPEVHLEDCKEVLLEFRKKLVDTKPKPAKKDLQKLSLNDDLFEAESDNDGQSEIKEDVSPKKKKKKSKEGEDRSADDLKKKKSKSAKVKEKPRTECESSSGTLGLDSKPKKRTSETKEDSKDPKKQRKEDSKEVKKKKGEVKDVKIKTKEDSKESKKSRKEKQGDAQFDTETSALDDALLQEIDNENPGLYSENKEEEQQVKCEKERVEEETAEKDSIADRQLDGSASNEDDSVEVKAKRKKKKNQKVEDYKEEGRKVEIKDIYLEKKSMLKKQKSQEKVKVVAAELEKVSAAPVSAQKALKVSAEERGRKAMESAEEEKEIKKSEMKEKSVKKESEKEEKIRKEQKVVKSYKDIKSALDMFNVASEEKKEYSENNCKREEPSLEYKFIEELKLKDSKVHKERRIKDEAETWNYVAAGGGREVVDVCHMENSDGKQQVLSLGMDMQLEWLTLEDFQKHLDGEDENHISAEPISSTLLRDAVKSGDYMTVKMALSSSEEYNLDQEDSSGMTLVMLAAAGGHDDLLRVLIRKGAKVNGRQKNGTTALIHAAEKNFLTTVAILLEAGAYVNMQQSSGETALMKACKRGNSDIVRLMIESGADCNILSKHQNSALHFAKQCNNVLVYEQLKSHLETLSRVAEDTIRDYFEARLVLLEPVFPIACHRLCEGPDFSTDFNYKPPQNVPEGSGILLFIFHANFFGKEVVARLCGPCSVQAVVLNDKFQLPVFLDSHFIYSFSPTAGLNKLFIRLAEAPTAKVKLLIGAYRVQLQ", "length": 794, "header": "tr|A0A8V0XQK4-1|A0A8V0XQK4_CHICK Computationally mapped isoform of M-phase phosphoprotein 8 OS=Gallus gallus OX=9031 GN=MPHOSPH8 PE=4 SV=1 CANONICAL=F1P0K0-1" }, "locus": { "chromosome": "1", "start_pos": 179110826, "end_pos": 179095920, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010012599.1", "url": "https://www.ensembl.org/id/ENSGALT00010012599.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010007163.1", "url": "https://www.ensembl.org/id/ENSGALP00010007163.1" } ] } }, { "isoform_ac": "F1P0K0-1", "url": "https://www.uniprot.org/uniprotkb/F1P0K0/entry#F1P0K0-1", "sequence": { "sequence": "MAAAGSGAEAAAARLEGAGEEEETAAAGDGENEVVDGGGAGGAAGAAAAGGESEEEEDVFEVEKILDVKTEGGVILYKVRWKGYTSDDDTWEPEVHLEDCKEVLLEFRKKLVDTKPKPAKKDLQKLSLNDDLFEAESDNDGQSEIKEDVSPKKKKKKSKEGEDRSADDLKKKKSKSAKVKEKPRTECESSSGTLGLDSKPKKRTSETKEDSKDPKKQRKEDSKEVKKKKGEVKDVKIKTKEDSKESKKSRKEKQGDAQFDTETSALDDALLQEIDNENPGLYSENKEEEQQVKCEKERVEEETAEKDSIADRQLDGSASNEDDSVEVKAKRKKKKNQKVEDYKEEGRKVEIKDIYLEKKSMLKKQKSQEKVKVVAAELEKVSAAPVSAQKALKVSAEERGRKAMESAEEEKEIKKSEMKEKSVKKESEKEEKIRKEQKVVKSYKDIKSALDMFNVASEEKKEYSENNCKREEPSLEYKFIEELKLKDSKVHKERRIKDEAETWNYVAAGGGREVVDVCHMENSDGKQQVLSLGMDMQLEWLTLEDFQKHLDGEDENHISAEPISSTLLRDAVKSGDYMTVKMALSSSEEYNLDQEDSSGMTLVMLAAAGGHDDLLRVLIRKGAKVNGRQKNGTTALIHAAEKNFLTTVAILLEAGAYVNMQQSSGETALMKACKRGNSDIVRLMIESGADCNILSKHQNSALHFAKQCNNVLVYEQLKSHLETLSRVAEDTIRDYFEARLVLLEPVFPIACHRLCEGPDFSTDFNYKPPQNVPEGSGILLFIFHANFFGKEVVARLCGPCSVQAVVLNDKFQLPVFLDSHFIYSFSPTAGLNKLFIRLAEAPTAKVKLLIGAYRVQLQ", "length": 858, "header": "tr|F1P0K0-1|F1P0K0_CHICK Isoform 1 of M-phase phosphoprotein 8 OS=Gallus gallus OX=9031 GN=MPHOSPH8 PE=4 SV=4 CANONICAL=F1P0K0-1" }, "locus": { "chromosome": "1", "start_pos": 179113953, "end_pos": 179095920, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010012601.1", "url": "https://www.ensembl.org/id/ENSGALT00010012601.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010007165.1", "url": "https://www.ensembl.org/id/ENSGALP00010007165.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:418957", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418957", "resource": "KEGG Pathway" }, { "id": "R-GGA-9764725", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9764725", "resource": "Reactome", "description": "Negative Regulation of CDH1 Gene Transcription" }, { "id": "R-GGA-9843970", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9843970", "resource": "Reactome", "description": "Regulation of endogenous retroelements by the Human Silencing Hub (HUSH) complex" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2QBY1-1", "protein_name": "M-phase phosphoprotein 8", "gene_name": "Mphosph8", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAAAAAAEESMSMAALAMSVPDSTVGSPRAEGEGVGVAREEKDATTKGTEAFGDSEEDGDDVFEVEKILDMKCEGGKNLYKVRWKGYTSDDDTWEPEIHLEDCKEVLLEFRKKVAENKAKAIKKDIQRLSLSNDIFEADFDSDQQSDTKEDTSPRKKKKKIKCKEEKSPDDLKKKKAKLGKLKDKFKSELESTSENLGFDIRTKKRILEAKEELKDSKKLKKDEIKENKELKKAKRAEIRDLKFKIREDIKDNRKTKKERSIECPLEFESPVPNESLSPEDDGEDFVSDNKEEKQKIRTVKDKAGQDTVQEGIFEKHLDDLVSTDEDAGARVRRKKKKPRIFDETKEIKKLENMDTFLERKMIPKKQRYQDKSRNNLELSRLPSPMSIQAPKSSRLSGEEKGLRSSDSAEEEKDTKKNESKEKYQKKYDLDKEEKCRKEPKGLKSFKEIRSAFDLFKKTEDKNDVLENNWKREEVPLDCKTTDDPKNKDKCSLKDRRNTRDETDTWAYIAAEGDQEVSDSVCQTDENSDGRQQILSLGMDLQLEWMKLEDFQKHLDGEDETFTTTNTIPSNLLRDAVKNGDYIAVKVALNSNEEYNLDQEDSSGMTLVMLAAAGGQDDLLRLLITKGAKVNGRQKNGTTALIHAAEKNFLTTVAILLEAGAFVNVQQSNGETALMKACKRGNSDIVRLVIECGADCNILSKHQNSALYFAKQCNNVLVYELLKSHLETLSRVAEETIRDYFESRLALLEPVFPIACHRLCEGPDFSTDFNYKPPQNIPEGSGVLLFIFHANFLGKEVIARLCGPCSVQAVVLNDKFQLPVFLDSHFVYSFSPVAGPNKLFIRLTEAPFAKVKLLIGAYRVQLH", "length": 863 }, "evidence": [ { "id": "F1P0K0", "url": "https://omabrowser.org/oma/group/F1P0K0/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0AAA9SNL2-1", "protein_name": "M-phase phosphoprotein 8", "gene_name": "MPHOSPH8", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAEAKAEAEGASVATVPGSGADGSGQLPAVEGEGFGARGKEKDAAAKGKEAGGDSEEDGENVFEVEKILDMKTEGGKVLYKVRWKGYTADDDTWEPEIHLEDCKEVLLEFRKKIADNKAKSVKKDIQRLSLNNDIFEANSDSDQQSETKEDTSPKKKKKKVRHKEEKSPDDLKKKKAKTGKLKDKPKPDLESSSESLGFDLRTKKRILEAKEELKESKKPKKDDIKETKELKKVKKGEIRDLKTKIRDDSKEIRKTKKEKCVESQVDSDLGVLSDSPLQEEDCEDLQVDNREEKQKFRGAKDKAEQEASLDPASDIQQDGSVSADEDEVKARRKKKKPRRTEELKESKKLENKSLFLEKKTTQKKQRNQDKGQSSTELDKPVPASALTPPRMSRPTDSPGEERETKKYEPKEKYQKKQDLDKEEKGRKEPKALKIAFKEIRNAFDLFKLTPEEKNDFPENNRKRDEIPPDYKVTEDHKAKENKPLLKERRNTRDETDTWAYIAAEGDQEVLDSAIRVEESPDGKQQVLSLGMDLQLEWMRLEDFQKHLDGEDENVTTADVIPSNLLRDAVKNGDYITVKVALNSSEEYNLDQEDSSGMTLLMLAAAGGQDDLLRLLLRKGAKVNGRQKNGTTALIHAAEKNFLTTVAILLEAGAFVNVQQNNGETALMKACKRGNSDIVRLVIECGADCNILSKHQNSALHFAKQCNNVLVYDLLKSHLETLSRVAEETIKDYFEARLALLEPVFPIACHRLCEGPDFSMDFNYRPPQTIPEGSGVLLFIFHANFLGKEVIARLCGPCSVQAVVLNDKFQLPVFLDSHFVYSFSPVAGLNKMFIRLTEAPSAKVKLLIGAYRVQLQ", "length": 856 }, "evidence": [ { "id": "F1P0K0", "url": "https://omabrowser.org/oma/group/F1P0K0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "B0S768-1", "protein_name": "2.4.2.30", "gene_name": "mphosph8", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MASGAERAEPGDSEQDEEDVYEVERIIDVRVEEGEVLYRVRWKNYSSEDDTWEPEAHLDDCKEVLLAYKKALAELKPKKEPAMLPMKSDLFDADSESDSDKEKPKESPMKKKKKKKKKKIEDSDDEMSVREKKKKKKKEKWREDKPLPAPESDEEESRDPSPAPSKKETKKRFIDSDDEDVPVTPKKQKKLDKPKDAGKVKKESGEERKKKKIKSKREIDSSDEDEKSDAPSESHTDDTTNTETNDSFKTTTKITEKPVRSESGGDLKQVKQKKDKSDIKLQGFKDLILEKKPKKPEASSAAAKDVGLNKIKSLTGSKSTSKSSRSEEEPDSSDTGAAASAPKAKVKSKSQEAAPSSQRLSSASSSSSSSTASTAPIKPREDEAKEEAGDKASASNLFEKFLLNCEAKDRAPRRQVDQNKSATPKGGSKNDKKTKPSKQSPGRKPDSDKTKDVPRSSQSPISMEVDEKQEKGSSELEKSEKSDEPNFKSKEELQREQREEEQRKRKEKMEEEERKRKERIEEEERKKKERIEEAQRERKARLEEAQRFAEEARQELERKSMAESIVSPDSTEDSRWKDKRRKRRDDSESRVFTTCDDNQDSQETVERSDKTPDRGPPSLNLGVELKLDWMTLEDFQKHLNGEDENLSPLALTPTELREAVKNGNYLAVKRALSSKEDYNLDQEDSSGMSLTLLAAAGGQDDILRLLIKKGVKVNSRQKTGTTALMHAADKNFLTTVAILLEAGAFVNAQTLGGETALMKACKRGNADVVRLLLEYGADCNILSKHKNTALYYAKLSNNLMVYDLIKDHMQTLSTVAEETIRAYFETRLALLEPVFPLACHRLCEGPDFSLEFNYKPPQHAPGEGSGILLFIFHANFLNEITARLCGPCSVHAVVLNDKFQLPIFLDSHFIYSFSPVQGANKMFIRLAESPTAKVKLLICAYRVQLQ", "length": 946 }, "evidence": [ { "id": "F1P0K0", "url": "https://omabrowser.org/oma/group/F1P0K0/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q3TYA6-1", "protein_name": "M-phase phosphoprotein 8", "gene_name": "Mphosph8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAAAEEGMSAAALVMSVPDSIGRSPESEGVGAGDEEKDAATKGTVAVGDSEEDGEDVFEVERILDMKCEGGKNLYKVRWKGYTSEDDTWEPEVHLEDCKEVLLEFRKKLAENKAKAVRKDIQRLSLNNDIFEADSDSDQQSDTKEDISPRKKKKKIKCKEETSPEDLRKKRTKMGKLKDKFKTELESTSEIIGFDVKTKKRIWEVKEELKDSKKPKKDEIKETKELKKANKRAEVRDLKIKIREDVKENRKTKKERYIESPLESESPNDSLILEDDSEDFISDNREENQNVRSVRDKTAQETVQEGIFEKHLDDLISIEEDAGTRVRRKKTKPRKFEEPKEIKKLESTNAFLERRAIPKKQRNQDKGISNLELNKLPSPVFAQTLKSSRLSGEEKSLKSPDLAEEEKEKKNEPKGKYQKRYDLDKEEKARKEPKVLKSFKEIRNAFDLFKKTTEEKNDVLENNSKREEISLDSKIMNDNKTKDKCSLKEKRNTRDETDTWAYIAAEGDQEVSDSVCQTDETSDGRQPVLSLGMDLQLEWMKLEDFQKHLDGEDEPFITTNRIPNNLLRDAVKNGDYIAVKVALNSNEEYNLDQEDSTGMTLVMLAAAGGQDDLLRLLITKGAKVNGRQKNGTTALIHAAEKNFLTTVAILLEAGAFVNVQQSNGETALMKACKRGNSDIVRLVIECGADCNILSKHQNSALYFAKQCNNVLVYELLKSHLETLSRVAEETIRDYFESRLALLEPVFPIACHRLCEGPDFSTDFNYMPPQNMPEGSGVLLFIFHANFLGKDVIARLCGPCSVQAVVLNDKFQLPVFLDSHFVYSFSPVAGPNKLFIRLTEAPFAKVKLLIGAYRVQLQ", "length": 858 }, "evidence": [ { "id": "F1P0K0", "url": "https://omabrowser.org/oma/group/F1P0K0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q99549-1", "protein_name": "M-phase phosphoprotein 8", "gene_name": "MPHOSPH8", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEQVAEGARVTAVPVSAADSTEELAEVEEGVGVVGEDNDAAARGAEAFGDSEEDGEDVFEVEKILDMKTEGGKVLYKVRWKGYTSDDDTWEPEIHLEDCKEVLLEFRKKIAENKAKAVRKDIQRLSLNNDIFEANSDSDQQSETKEDTSPKKKKKKLRQREEKSPDDLKKKKAKAGKLKDKSKPDLESSLESLVFDLRTKKRISEAKEELKESKKPKKDEVKETKELKKVKKGEIRDLKTKTREDPKENRKTKKEKFVESQVESESSVLNDSPFPEDDSEGLHSDSREEKQNTKSARERAGQDMGLEHGFEKPLDSAMSAEEDTDVRGRRKKKTPRKAEDTRENRKLENKNAFLEKKTVPKKQRNQDRSKSAAELEKLMPVSAQTPKGRRLSGEERGLWSTDSAEEDKETKRNESKEKYQKRHDSDKEEKGRKEPKGLKTLKEIRNAFDLFKLTPEEKNDVSENNRKREEIPLDFKTIDDHKTKENKQSLKERRNTRDETDTWAYIAAEGDQEVLDSVCQADENSDGRQQILSLGMDLQLEWMKLEDFQKHLDGKDENFAATDAIPSNVLRDAVKNGDYITVKVALNSNEEYNLDQEDSSGMTLVMLAAAGGQDDLLRLLITKGAKVNGRQKNGTTALIHAAEKNFLTTVAILLEAGAFVNVQQSNGETALMKACKRGNSDIVRLVIECGADCNILSKHQNSALHFAKQSNNVLVYDLLKNHLETLSRVAEETIKDYFEARLALLEPVFPIACHRLCEGPDFSTDFNYKPPQNIPEGSGILLFIFHANFLGKEVIARLCGPCSVQAVVLNDKFQLPVFLDSHFVYSFSPVAGPNKLFIRLTEAPSAKVKLLIGAYRVQLQ", "length": 860 }, "evidence": [ { "id": "F1P0K0", "url": "https://omabrowser.org/oma/group/F1P0K0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 7, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1P0K0", "url": "https://www.uniprot.org/uniprotkb/F1P0K0" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "F1P0K0", "url": "https://www.uniprot.org/uniprotkb/F1P0K0" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1P0K0", "url": "https://www.uniprot.org/uniprotkb/F1P0K0" } ], "pmid": "" }, { "name": "heterochromatin", "id": "GO:0000792", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000792", "evidence": [ { "database": "UniProtKB", "id": "F1P0K0", "url": "https://www.uniprot.org/uniprotkb/F1P0K0" } ], "pmid": "" }, { "name": "nucleosome", "id": "GO:0000786", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000786", "evidence": [ { "database": "UniProtKB", "id": "F1P0K0", "url": "https://www.uniprot.org/uniprotkb/F1P0K0" } ], "pmid": "" }, { "name": "HUSH2 complex", "id": "GO:0140286", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140286", "evidence": [ { "database": "UniProtKB", "id": "F1P0K0", "url": "https://www.uniprot.org/uniprotkb/F1P0K0" } ], "pmid": "" }, { "name": "HUSH complex", "id": "GO:0140283", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140283", "evidence": [ { "database": "UniProtKB", "id": "F1P0K0", "url": "https://www.uniprot.org/uniprotkb/F1P0K0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "F1P0K0", "url": "https://www.uniprot.org/uniprotkb/F1P0K0" } ], "pmid": "" }, { "name": "histone H3K9me2/3 reader activity", "id": "GO:0062072", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0062072", "evidence": [ { "database": "UniProtKB", "id": "F1P0K0", "url": "https://www.uniprot.org/uniprotkb/F1P0K0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "negative regulation of type I interferon production", "id": "GO:0032480", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032480", "evidence": [ { "database": "UniProtKB", "id": "F1P0K0", "url": "https://www.uniprot.org/uniprotkb/F1P0K0" } ], "pmid": "" }, { "name": "negative regulation of gene expression via chromosomal CpG island methylation", "id": "GO:0044027", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044027", "evidence": [ { "database": "UniProtKB", "id": "F1P0K0", "url": "https://www.uniprot.org/uniprotkb/F1P0K0" } ], "pmid": "" }, { "name": "constitutive heterochromatin formation", "id": "GO:0140719", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140719", "evidence": [ { "database": "UniProtKB", "id": "F1P0K0", "url": "https://www.uniprot.org/uniprotkb/F1P0K0" } ], "pmid": "" }, { "name": "transposable element silencing by heterochromatin formation", "id": "GO:0141005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0141005", "evidence": [ { "database": "UniProtKB", "id": "F1P0K0", "url": "https://www.uniprot.org/uniprotkb/F1P0K0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 631, "end_pos": 633, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1P0K0-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 858, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1P0K0-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1P0K0" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 631, "end_pos": 633 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1NNH9-1", "uniprot_ac": "F1NNH9", "uniprot_id": "F1NNH9_CHICK", "mass": { "chemical_mass": 65075.0, "monoisotopic_mass": 65075.0 }, "refseq": { "ac": "XP_040516135", "name": "mitochondrial import receptor subunit TOM70", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040516135" }, "gene_names": [ { "name": "TOMM70", "type": "recommended", "evidence": [ { "id": "F1NNH9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NNH9" } ] }, { "name": "TOMM70", "type": "synonym", "evidence": [ { "id": "XP_040516135", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040516135" } ] } ], "protein_names": [ { "name": "Mitochondrial import receptor subunit TOM70", "type": "recommended", "evidence": [ { "id": "F1NNH9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NNH9/entry#names_and_taxonomy" } ] }, { "name": "Mitochondrial precursor proteins import receptor", "type": "synonym", "evidence": [ { "id": "F1NNH9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NNH9/entry#names_and_taxonomy" } ] }, { "name": "Translocase of outer membrane 70 kDa subunit", "type": "synonym", "evidence": [ { "id": "F1NNH9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NNH9/entry#names_and_taxonomy" } ] }, { "name": "Translocase of outer mitochondrial membrane protein 70", "type": "synonym", "evidence": [ { "id": "F1NNH9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NNH9/entry#names_and_taxonomy" } ] }, { "name": "mitochondrial import receptor subunit TOM70", "type": "synonym", "evidence": [ { "id": "XP_040516135", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040516135" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052573.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040516135", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040516135" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NNH9", "url": "https://www.uniprot.org/uniprotkb/F1NNH9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TOMM70", "url": "https://www.uniprot.org/uniprotkb/F1NNH9", "locus": { "chromosome": "1", "start_pos": 85119683, "end_pos": 85142415, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010005649", "url": "https://www.ensembl.org/id/ENSGALG00010005649" } ] } } ], "crossref": [ { "id": "F1NNH9", "url": "https://alphafold.ebi.ac.uk/entry/F1NNH9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000015285", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000015285", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "418387", "url": "https://www.ncbi.nlm.nih.gov/gene/418387", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011990", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011990", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019734", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019734", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:418387", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418387", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QWRGDIE", "url": "https://omabrowser.org/oma/group/QWRGDIE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XMV0", "url": "https://www.orthodb.org/?gene=A0A8V0XMV0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NNH9", "url": "https://www.orthodb.org/?gene=F1NNH9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46208", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46208", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46208:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46208:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00515", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00515", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13181", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13181", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-168928", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-168928", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-5205685", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5205685", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-5689880", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5689880", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_040516135", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040516135", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0XMV0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMV0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XMV0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMV0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NNH9", "url": "https://www.uniprot.org/uniprotkb/F1NNH9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NNH9-1", "url": "https://www.uniprot.org/uniprotkb/F1NNH9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAASKPVEAPGGGGSGTGLSRWQLALVLGAPILLGAGAVYLWGRRAARRGGKGASERKTPEGRASPGPYSGGAQPDGPGHEEMSPLDRAQAAKNKGNKYFKAGRYEQAIQCYTEAISLCPPERNLDLSTFYQNRAAAYEQLQKWTEVAQDCTKAVELNPKYVKALFRRAKAHEKLDNKKECLEDVTAVCILEAFQNQQSMLLADKVLKLLGKEKAKEKYKNREPLMPSPQFIKSYFSSFTDDIISQPLLKGEKSDEDKDKEGEASEVKENSGYLRAKQYMEEENYDKIISECTKEIEAKGKYMAEALLLRATFYLLIGNANAAKPDLDQVISMEDANVKLRANALIKRGSMYMQQQQPALSTQDFNMAADIDPQNADVYHHRGQLKILLDQIEEAVEDFDECIRLRPDSALAQAQKCFALYRQAYTGNNPLPVQVAMKGFEDVIKKFPKCAEGYALYAQALTDQQQFGKADEMYDKCIDLEPDNATTYVHKGLLQLQWKQDLDKGLELISKAIEIDNKCDFAYETMGTIEVQRGNLDKAIEMFNKAINLAKSEMEMAHLYSLCDAAYAQTEVAKKYGLKPPTL", "length": 583, "header": "tr|F1NNH9-1|F1NNH9_CHICK Isoform 1 of Mitochondrial import receptor subunit TOM70 OS=Gallus gallus OX=9031 GN=TOMM70 PE=1 SV=4 CANONICAL=F1NNH9-1" }, "isoforms": [ { "isoform_ac": "A0A8V0XMV0-1", "url": "https://www.uniprot.org/uniprotkb/F1NNH9/entry#A0A8V0XMV0-1", "sequence": { "sequence": "MICSEQAMHRGQKLCCSRLQTASGASTTVCLLLSPLDRAQAAKNKGNKYFKAGRYEQAIQCYTEAISLCPPERNLDLSTFYQNRAAAYEQLQKWTEVAQDCTKAVELNPKYVKALFRRAKAHEKLDNKKECLEDVTAVCILEAFQNQQSMLLADKVLKLLGKEKAKEKYKNREPLMPSPQFIKSYFSSFTDDIISQPLLKGEKSDEDKDKEGEASEVKENSGYLRAKQYMEEENYDKIISECTKEIEAKGKYMAEALLLRATFYLLIGNANAAKPDLDQVISMEDANVKLRANALIKRGSMYMQQQQPALSTQDFNMAADIDPQNADVYHHRGQLKILLDQIEEAVEDFDECIRLRPDSALAQAQKCFALYRQAYTGNNPLPVQVAMKGFEDVIKKFPKCAEGYALYAQALTDQQQFGKADEMYDKCIDLEPDNATTYVHKGLLQLQWKQDLDKGLELISKAIEIDNKCDFAYETMGTIEVQRGNLDKAIEMFNKAINLAKSEMEMAHLYSLCDAAYAQTEVAKKYGLKPPTL", "length": 533, "header": "tr|A0A8V0XMV0-1|A0A8V0XMV0_CHICK Computationally mapped isoform of Mitochondrial import receptor subunit TOM70 OS=Gallus gallus OX=9031 GN=TOMM70 PE=1 SV=1 CANONICAL=F1NNH9-1" }, "locus": { "chromosome": "1", "start_pos": 85141377, "end_pos": 85121720, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010013515.1", "url": "https://www.ensembl.org/id/ENSGALT00010013515.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010008019.1", "url": "https://www.ensembl.org/id/ENSGALP00010008019.1" } ] } }, { "isoform_ac": "F1NNH9-1", "url": "https://www.uniprot.org/uniprotkb/F1NNH9/entry#F1NNH9-1", "sequence": { "sequence": "MAASKPVEAPGGGGSGTGLSRWQLALVLGAPILLGAGAVYLWGRRAARRGGKGASERKTPEGRASPGPYSGGAQPDGPGHEEMSPLDRAQAAKNKGNKYFKAGRYEQAIQCYTEAISLCPPERNLDLSTFYQNRAAAYEQLQKWTEVAQDCTKAVELNPKYVKALFRRAKAHEKLDNKKECLEDVTAVCILEAFQNQQSMLLADKVLKLLGKEKAKEKYKNREPLMPSPQFIKSYFSSFTDDIISQPLLKGEKSDEDKDKEGEASEVKENSGYLRAKQYMEEENYDKIISECTKEIEAKGKYMAEALLLRATFYLLIGNANAAKPDLDQVISMEDANVKLRANALIKRGSMYMQQQQPALSTQDFNMAADIDPQNADVYHHRGQLKILLDQIEEAVEDFDECIRLRPDSALAQAQKCFALYRQAYTGNNPLPVQVAMKGFEDVIKKFPKCAEGYALYAQALTDQQQFGKADEMYDKCIDLEPDNATTYVHKGLLQLQWKQDLDKGLELISKAIEIDNKCDFAYETMGTIEVQRGNLDKAIEMFNKAINLAKSEMEMAHLYSLCDAAYAQTEVAKKYGLKPPTL", "length": 583, "header": "tr|F1NNH9-1|F1NNH9_CHICK Isoform 1 of Mitochondrial import receptor subunit TOM70 OS=Gallus gallus OX=9031 GN=TOMM70 PE=1 SV=4 CANONICAL=F1NNH9-1" }, "locus": { "chromosome": "1", "start_pos": 85142392, "end_pos": 85121720, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010013520.1", "url": "https://www.ensembl.org/id/ENSGALT00010013520.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010008022.1", "url": "https://www.ensembl.org/id/ENSGALP00010008022.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:418387", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418387", "resource": "KEGG Pathway" }, { "id": "R-GGA-168928", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-168928", "resource": "Reactome", "description": "DDX58/IFIH1-mediated induction of interferon-alpha/beta" }, { "id": "R-GGA-5205685", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5205685", "resource": "Reactome", "description": "PINK1-PRKN Mediated Mitophagy" }, { "id": "R-GGA-5689880", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5689880", "resource": "Reactome", "description": "Ub-specific processing proteases" } ], "orthologs": [ { "uniprot_canonical_ac": "O94826-1", "protein_name": "Mitochondrial import receptor subunit TOM70", "gene_name": "TOMM70", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAASKPVEAAVVAAAVPSSGSGVGGGGTAGPGTGGLPRWQLALAVGAPLLLGAGAIYLWSRQQRRREARGRGDASGLKRNSERKTPEGRASPAPGSGHPEGPGAHLDMNSLDRAQAAKNKGNKYFKAGKYEQAIQCYTEAISLCPTEKNVDLSTFYQNRAAAFEQLQKWKEVAQDCTKAVELNPKYVKALFRRAKAHEKLDNKKECLEDVTAVCILEGFQNQQSMLLADKVLKLLGKEKAKEKYKNREPLMPSPQFIKSYFSSFTDDIISQPMLKGEKSDEDKDKEGEALEVKENSGYLKAKQYMEEENYDKIISECSKEIDAEGKYMAEALLLRATFYLLIGNANAAKPDLDKVISLKEANVKLRANALIKRGSMYMQQQQPLLSTQDFNMAADIDPQNADVYHHRGQLKILLDQVEEAVADFDECIRLRPESALAQAQKCFALYRQAYTGNNSSQIQAAMKGFEEVIKKFPRCAEGYALYAQALTDQQQFGKADEMYDKCIDLEPDNATTYVHKGLLQLQWKQDLDRGLELISKAIEIDNKCDFAYETMGTIEVQRGNMEKAIDMFNKAINLAKSEMEMAHLYSLCDAAHAQTEVAKKYGLKPPTL", "length": 608 }, "evidence": [ { "id": "F1NNH9", "url": "https://omabrowser.org/oma/group/F1NNH9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P07213-1", "protein_name": "Mitochondrial import receptor subunit TOM70", "gene_name": "TOM70", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MKSFITRNKTAILATVAATGTAIGAYYYYNQLQQQQQRGKKNTINKDEKKDTKDSQKETEGAKKSTAPSNPPIYPVSSNGEPDFSNKANFTAEEKDKYALALKDKGNQFFRNKKYDDAIKYYNWALELKEDPVFYSNLSACYVSVGDLKKVVEMSTKALELKPDYSKVLLRRASANEGLGKFADAMFDLSVLSLNGDFNDASIEPMLERNLNKQAMSKLKEKFGDIDTATATPTELSTQPAKERKDKQENLPSVTSMASFFGIFKPELTFANYDESNEADKELMNGLSNLYKRSPESYDKADESFTKAARLFEEQLDKNNEDEKLKEKLAISLEHTGIFKFLKNDPLGAHEDIKKAIELFPRVNSYIYMALIMADRNDSTEYYNYFDKALKLDSNNSSVYYHRGQMNFILQNYDQAGKDFDKAKELDPENIFPYIQLACLAYRENKFDDCETLFSEAKRKFPEAPEVPNFFAEILTDKNDFDKALKQYDLAIELENKLDGIYVGIAPLVGKATLLTRNPTVENFIEATNLLEKASKLDPRSEQAKIGLAQMKLQQEDIDEAITLFEESADLARTMEEKLQAITFAEAAKVQQRIRSDPVLAKKIQETLAKLREQGLM", "length": 617 }, "evidence": [ { "id": "F1NNH9", "url": "https://omabrowser.org/oma/group/F1NNH9/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q75Q39-1", "protein_name": "Mitochondrial import receptor subunit TOM70", "gene_name": "Tomm70", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAASKPVEAAMAAAAAPASGNGVGSSGGTAAPGSGAGTLPRWHVALAIGAPLLLGAGAMYLWSRRRRRREAGGRGDASGLKRNSERKTPEGRASPALGSGPDGSGDSLEMSSLDRAQAAKNKGNKYFKAGKYEQAIQCYTEAISLCPTEKNADLSTFYQNRAAAFEQLQKWKEVAQDCTKAVELNPKYVKALFRRAKAHEKLDNKKECLEDVTAVCILEGFQNEQSMLLADKVLKLLGKENAKEKYKNREPLMPSPQFIKSYFSSFTDDIISQPMLKGEKSDEDKDKEGEALEVKENSGYLKAKQYMEEENYDKIISECSKEIDAQGKYMAEALLLRATFYLLIGSANAAKPDLDKVISLKEANVKLRANALIKRGTMCMQQQQPMLSTQDFNMAAEIDPMNSDVYHHRGQLKILLDLVEEAVADFDACIRLRPKFALAQAQKCFALYRQAYTANNSSQVQAAMKGFEEVIKKFPRCAEGYALYAQALTDQQQFGKADEMYDKCIDLEPDNATTYVHKGLLQLQWKQDLDKGLELISKAIEIDNKCDFAYETMGTIEVQRGNMEKAIDMFNKAINLAKSEMEMAHLYSLCDAAHAQTEVAKKYGLKPPTL", "length": 610 }, "evidence": [ { "id": "F1NNH9", "url": "https://omabrowser.org/oma/group/F1NNH9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9CZW5-1", "protein_name": "Mitochondrial import receptor subunit TOM70", "gene_name": "Tomm70", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAASKPIEAAMAAAAAPGSGNGVGGGGGTAGPGSGAGTLPRWHVALAIGAPLLLGAGAMYLWSRRRRRREAGGRGDASGLKRNSERKTPEGRASPALGSGHHDGSGDSLEMSSLDRAQAAKNKGNKYFKAGKYEQAIQCYTEAISLCPTEKNVDLSTFYQNRAAAFEQLQKWKEVAQDCTKAVELNPKYVKALFRRAKAHEKLDNKKECLEDVTAVCILEGFQNEQSMLLADKVLKLLGKENAKEKYKNREPLMPSPQFIKSYFSSFTDDIISQPMLKGEKSDEDKDKEGEALEVKENSGYLKAKQYMEEENYDKIISECSKEIDAQGKYMAEALLLRATFYLLIGSANAAKPDLDKVISLKEANVKLRANALIKRGTMCMQQQQPMLSTQDFNMAAEIDPMNSDVYHHRGQLKILLDLVEEAVADFDACIRLRPKFALAQAQKCFALYRQAYTANNSSQVQAAMKGFEEIIKKFPRCAEGYALYAQALTDQQQFGKADEMYDKCIDLEPDNATTYVHKGLLQLQWKQDLDKGLELISKAIEIDNKCDFAYETMGTIEVQRGNMEKAIDMFNKAINLAKSEMEMAHLYSLCDAAHAQTEVAKKYGLKPPTL", "length": 611 }, "evidence": [ { "id": "F1NNH9", "url": "https://omabrowser.org/oma/group/F1NNH9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VKC8-1", "protein_name": "Translocase of outer membrane 70, isoform B", "gene_name": "Tom70", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MAMTLNIGSMKLTKWQLALILGTPLAIGLGTYAVKSWTAASKELDGEKKRPKAKIEKQAISLDGTAPDQELERNQKSAELGEKLSPLKEANNYKTEGNNCYRNGKYDEAIKFYDKAIDKCPKEHRTDMAIFYQNRAASYEMLKKWSNVKEDCTASLEFNPRYAKAYYRRARAHEATKDMNECLDDVTATCILEMFQNNQTIMFADRVLKETGRLDAEKGMRNRVPVVPSACFVNTYTRSFIADPLQTMKVPAPKSDAPPKGFLRAHLAFLEEKYEEIIPACTEEIESSEAEAQYKVEALLMRGTFHLLCGSYVESQQDFDAIIANDYADPNLRAYAYIKRAALYIQLDQREKGIADFAEAERLNPENPDVYHQRAQILLLLEQIEPALAEFEKAVSIAPNHAIAFVQKCYAEYRLSLLAGDQRRLESVMHTFQNAIERFPSCVECYSLTAQVLADQQQFTQAEEYYKKAMVLAPTNPALIVHQAIMVLQWRGDINLAVQLLNKAIEVDPKCELAYETLGTVEVQRAQLTRAVELFEKALLYAKSQAELVHVYSLRNAAVAQINVTKKLGIDMNSVSAMAQSGLMAQGVA", "length": 589 }, "evidence": [ { "id": "F1NNH9", "url": "https://omabrowser.org/oma/group/F1NNH9/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "mitochondrial outer membrane", "id": "GO:0005741", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005741", "evidence": [ { "database": "UniProtKB", "id": "F1NNH9", "url": "https://www.uniprot.org/uniprotkb/F1NNH9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "protein-macromolecule adaptor activity", "id": "GO:0030674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030674", "evidence": [ { "database": "UniProtKB", "id": "F1NNH9", "url": "https://www.uniprot.org/uniprotkb/F1NNH9" } ], "pmid": "" }, { "name": "mitochondrion targeting sequence binding", "id": "GO:0030943", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030943", "evidence": [ { "database": "UniProtKB", "id": "F1NNH9", "url": "https://www.uniprot.org/uniprotkb/F1NNH9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 7, "go_terms": [ { "name": "protein insertion into mitochondrial inner membrane", "id": "GO:0045039", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045039", "evidence": [ { "database": "UniProtKB", "id": "F1NNH9", "url": "https://www.uniprot.org/uniprotkb/F1NNH9" } ], "pmid": "" }, { "name": "positive regulation of defense response to virus by host", "id": "GO:0002230", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002230", "evidence": [ { "database": "UniProtKB", "id": "F1NNH9", "url": "https://www.uniprot.org/uniprotkb/F1NNH9" } ], "pmid": "" }, { "name": "regulation of apoptotic process", "id": "GO:0042981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042981", "evidence": [ { "database": "UniProtKB", "id": "F1NNH9", "url": "https://www.uniprot.org/uniprotkb/F1NNH9" } ], "pmid": "" }, { "name": "activation of innate immune response", "id": "GO:0002218", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002218", "evidence": [ { "database": "UniProtKB", "id": "F1NNH9", "url": "https://www.uniprot.org/uniprotkb/F1NNH9" } ], "pmid": "" }, { "name": "cellular response to virus", "id": "GO:0098586", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098586", "evidence": [ { "database": "UniProtKB", "id": "F1NNH9", "url": "https://www.uniprot.org/uniprotkb/F1NNH9" } ], "pmid": "" }, { "name": "protein import into mitochondrial matrix", "id": "GO:0030150", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030150", "evidence": [ { "database": "UniProtKB", "id": "F1NNH9", "url": "https://www.uniprot.org/uniprotkb/F1NNH9" } ], "pmid": "" }, { "name": "positive regulation of interferon-beta production", "id": "GO:0032728", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032728", "evidence": [ { "database": "UniProtKB", "id": "F1NNH9", "url": "https://www.uniprot.org/uniprotkb/F1NNH9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { 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"table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1NZW0-1", "uniprot_ac": "F1NZW0", "uniprot_id": "F1NZW0_CHICK", "mass": { "chemical_mass": 103213.0, "monoisotopic_mass": 103213.0 }, "refseq": {}, "gene_names": [ { "name": "TAF3", "type": "recommended", "evidence": [ { "id": "F1NZW0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NZW0" } ] } ], "protein_names": [ { "name": "Transcription initiation factor TFIID subunit 3", "type": "recommended", "evidence": [ { "id": "F1NZW0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NZW0/entry#names_and_taxonomy" } ] }, { "name": "TBP-associated factor 3", "type": "synonym", "evidence": [ { "id": "F1NZW0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NZW0/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "The TFIID basal transcription factor complex plays a major role in the initiation of RNA polymerase II (Pol II)-dependent transcription. TFIID recognizes and binds promoters with or without a TATA box via its subunit TBP, a TATA-box-binding protein, and promotes assembly of the pre-initiation complex (PIC). The TFIID complex consists of TBP and TBP-associated factors (TAFs), including TAF1, TAF2, TAF3, TAF4, TAF5, TAF6, TAF7, TAF8, TAF9, TAF10, TAF11, TAF12 and TAF13. The TFIID complex structure can be divided into 3 modules TFIID-A, TFIID-B, and TFIID-C. TAF3 forms the TFIID-A module together with TAF5 and TBP. Required in complex with TBPL2 for the differentiation of myoblasts into myocytes. The TAF3-TBPL2 complex replaces TFIID at specific promoters at an early stage in the differentiation process.", "evidence": [ { "database": "UniProtKB", "id": "F1NZW0", "url": "https://www.uniprot.org/uniprotkb/F1NZW0#function" }, { "database": "UniProtKB", "id": "ARBA00057922", "url": "https://www.uniprot.org/uniprotkb/ARBA00057922#function" }, { "database": "UniProtKB", "id": "A0A8V0XQG9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQG9#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NZW0", "url": "https://www.uniprot.org/uniprotkb/F1NZW0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TAF3", "url": "https://www.uniprot.org/uniprotkb/F1NZW0", "locus": { "chromosome": "1", "start_pos": 4988615, "end_pos": 4874712, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010005292", "url": "https://www.ensembl.org/id/ENSGALG00010005292" } ] } } ], "crossref": [ { "id": "F1NZW0", "url": "https://alphafold.ebi.ac.uk/entry/F1NZW0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000006731", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000006731", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd15522", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15522", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd22916", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22916", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "419107", "url": "https://www.ncbi.nlm.nih.gov/gene/419107", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001965", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001965", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006565", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006565", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009072", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009072", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011011", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011011", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019786", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019786", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019787", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019787", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:419107", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419107", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "ENIHMRQ", "url": "https://omabrowser.org/oma/group/ENIHMRQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XQG9", "url": "https://www.orthodb.org/?gene=A0A8V0XQG9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NZW0", "url": "https://www.orthodb.org/?gene=F1NZW0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46452", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46452", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46452:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46452:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00628", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00628", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07524", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07524", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-674695", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-674695", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-73776", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-73776", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-73779", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-73779", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-75953", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-75953", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-76042", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-76042", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001026012", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026012", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0XQG9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQG9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XQG9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQG9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NZW0", "url": "https://www.uniprot.org/uniprotkb/F1NZW0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NZW0-1", "url": "https://www.uniprot.org/uniprotkb/F1NZW0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MCETYSRWLLRVSVAQICQALGWDSVQVSACDLLTDVLQRYLQGLGRGCHRYCELYGRTDPILDDVGDAFKLMGVNLHELEDYIHNIEPVTFAHQIPSFPVSKNNVLQFPQPGSKDAEERKEYIPDYMPPIVSSQEEEEEEQVPTDGGTSAEAMQVPLEEEGDMEEDEAINDENYLSKRPLESPDAEEFPPMKRPKLSVSKGDALDGALEPREPLSSINTQKVPPMLSPVHVQDSTDLAPPSPEPPMLAPIAKSQVPTPKTLESKPPAPKTKSKTSSPGQKTKSPKTTPSPVVAGSPIRSPKTGSKEKKSPGRAKSPKSPKSPKAPVHVPPPPVKPETPSRTPLAALSDKIGKENIQVKQGQTPPEPVTKPNIENQTKKLPVMDKTIDDSIDAVIARACAEREPDPFEFSSGSESEGEIFTSPKRLSVSETTATTPKPSVSTNCSNKAGATPVPPSGGTSSSDISWTMDDSIDEVIRKANMGTPSNPPANFTYFSSPSASPPTPEPLLKVYEEKTKLASSVEVKKKLKKELKTKMKKKEKQKEKDKEKSKEKNKEKEKNKEKDKDKEGNKEAKFQWKELLKDDEHDPYKFKLKDFEDADTKVKLKDGNTKKEKEKHKDKKKEKEKGKKDKDKKDKEKVKDKSKEDKIKPPSAPLVLPPKEMSLPLFSTPTAMRLPSMLPSLSPMLPEKLFEDKEKPKEKKKDKKEKKKKKEREKDKEKEKKDKEKERKEREKKEKEKEKHKHEKIKVEPVVPAPSPVIPRLTLRVGAGQDKIVISKVVPAPEAKPATPVSRPKTPPPVPSPVPAPVHVTPPPAPVPAPPQPTVSPALLPPASPAVSAAGGSKAPVRSVVTETVSTYVIRDEWGNQIWFCPGCNKPDDGSPMIGCDDCDDWYHWPCVGITAAPPEEMQWFCSKCANKKKDKKHKKRKHRAH", "length": 930, "header": "tr|F1NZW0-1|F1NZW0_CHICK Isoform 1 of Transcription initiation factor TFIID subunit 3 OS=Gallus gallus OX=9031 GN=TAF3 PE=3 SV=2 CANONICAL=F1NZW0-1" }, "isoforms": [ { "isoform_ac": "A0A8V0XQG9-1", "url": "https://www.uniprot.org/uniprotkb/F1NZW0/entry#A0A8V0XQG9-1", "sequence": { "sequence": "MCETYSRWLLRVSVAQICQALGWDSVQVSACDLLTDVLQRYLQGLGRGCHRYCELYGRTDPILDDVGDAFKLMGVNLHELEDYIHNIEPVTFAHQIPSFPVSKNNVLQFPQPGSKDAEERKEYIPDYMPPIVSSQEEEEEEQVPTDGGTSAEAMQVPLEEEGDMEEDEAINDENYLSKRPLESPDAEEFPPMKRPKLSVSKGDALDGALEPREPLSSINTQKVPPMLSPVHVQDSTDLAPPSPEPPMLAPIAKSQVPTPKTLESKPPAPKTKSKTSSPGQKTKSPKTTPSPVVAGSPIRSPKTGSKEKKSPGRAKSPKSPKSPKAPVHVPPPPVKPETPSRTPLAALSDKIGKENIQVKQGQTPPEPVTKPNIENQTKKLPVMDKTIDDSIDAVIARACAEREPDPFEFSSGSESEGEIFTSPKRLSVSETTATTPKPSVSTNCSNKAGATPVPPSGGTSSSDISWTMDDSIDEVIRKANMGTPSNPPANFTYFSSPSASPPTPEPLLKVYEEKTKLASSVEVKKKLKKELKTKMKKKEKQKEKDKEKSKEKNKEKEKNKEKDKDKEGNKEAKFQWKELLKDDEHDPYKFKLKDFEDADTKVKLKDGNTKKEKEKHKDKKKEKEKDKEKVKDKSKEDKIKPPSAPLVLPPKEMSLPLFSTPTAMRLPSMLPSLSPMLPEKLFEDKEKPKEKKKDKKEKKKKKEREKDKEKEKKDKEKERKEREKKEKEKEKHKHEKIKVEPVVPAPSPVIPRLTLRVGAGQDKIVISKVVPAPEAKPATPVSRPKTPPPVPSPVPAPVHVTPPPAPVPAPPQPTVSPALLPPASPAVSAAGGSKAPVRSVVTETVSTYVIRDEWGNQIWFCPGCNKPDDGSPMIGCDDCDDWYHWPCVGITAAPPEEMQWFCSKCANKKKDKKHKKRKHRAH", "length": 922, "header": "tr|A0A8V0XQG9-1|A0A8V0XQG9_CHICK Computationally mapped isoform of Transcription initiation factor TFIID subunit 3 OS=Gallus gallus OX=9031 GN=TAF3 PE=3 SV=1 CANONICAL=F1NZW0-1" }, "locus": { "chromosome": "1", "start_pos": 4986633, "end_pos": 4874815, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010012558.1", "url": "https://www.ensembl.org/id/ENSGALT00010012558.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010007122.1", "url": "https://www.ensembl.org/id/ENSGALP00010007122.1" } ] } }, { "isoform_ac": "F1NZW0-1", "url": "https://www.uniprot.org/uniprotkb/F1NZW0/entry#F1NZW0-1", "sequence": { "sequence": "MCETYSRWLLRVSVAQICQALGWDSVQVSACDLLTDVLQRYLQGLGRGCHRYCELYGRTDPILDDVGDAFKLMGVNLHELEDYIHNIEPVTFAHQIPSFPVSKNNVLQFPQPGSKDAEERKEYIPDYMPPIVSSQEEEEEEQVPTDGGTSAEAMQVPLEEEGDMEEDEAINDENYLSKRPLESPDAEEFPPMKRPKLSVSKGDALDGALEPREPLSSINTQKVPPMLSPVHVQDSTDLAPPSPEPPMLAPIAKSQVPTPKTLESKPPAPKTKSKTSSPGQKTKSPKTTPSPVVAGSPIRSPKTGSKEKKSPGRAKSPKSPKSPKAPVHVPPPPVKPETPSRTPLAALSDKIGKENIQVKQGQTPPEPVTKPNIENQTKKLPVMDKTIDDSIDAVIARACAEREPDPFEFSSGSESEGEIFTSPKRLSVSETTATTPKPSVSTNCSNKAGATPVPPSGGTSSSDISWTMDDSIDEVIRKANMGTPSNPPANFTYFSSPSASPPTPEPLLKVYEEKTKLASSVEVKKKLKKELKTKMKKKEKQKEKDKEKSKEKNKEKEKNKEKDKDKEGNKEAKFQWKELLKDDEHDPYKFKLKDFEDADTKVKLKDGNTKKEKEKHKDKKKEKEKGKKDKDKKDKEKVKDKSKEDKIKPPSAPLVLPPKEMSLPLFSTPTAMRLPSMLPSLSPMLPEKLFEDKEKPKEKKKDKKEKKKKKEREKDKEKEKKDKEKERKEREKKEKEKEKHKHEKIKVEPVVPAPSPVIPRLTLRVGAGQDKIVISKVVPAPEAKPATPVSRPKTPPPVPSPVPAPVHVTPPPAPVPAPPQPTVSPALLPPASPAVSAAGGSKAPVRSVVTETVSTYVIRDEWGNQIWFCPGCNKPDDGSPMIGCDDCDDWYHWPCVGITAAPPEEMQWFCSKCANKKKDKKHKKRKHRAH", "length": 930, "header": "tr|F1NZW0-1|F1NZW0_CHICK Isoform 1 of Transcription initiation factor TFIID subunit 3 OS=Gallus gallus OX=9031 GN=TAF3 PE=3 SV=2 CANONICAL=F1NZW0-1" }, "locus": { "chromosome": "1", "start_pos": 4986633, "end_pos": 4874815, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010012556.1", "url": "https://www.ensembl.org/id/ENSGALT00010012556.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010007120.1", "url": "https://www.ensembl.org/id/ENSGALP00010007120.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 503, "start_aa": "Thr", "end_pos": 503, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr503", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 809, "start_aa": "Thr", "end_pos": 809, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr809", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 822, "start_aa": "Thr", "end_pos": 822, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr822", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:419107", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419107", "resource": "KEGG Pathway" }, { "id": "R-GGA-674695", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-674695", "resource": "Reactome", "description": "RNA Polymerase II Pre-transcription Events" }, { "id": "R-GGA-73776", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-73776", "resource": "Reactome", "description": "RNA Polymerase II Promoter Escape" }, { "id": "R-GGA-73779", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-73779", "resource": "Reactome", "description": "RNA Polymerase II Transcription Pre-Initiation And Promoter Opening" }, { "id": "R-GGA-75953", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-75953", "resource": "Reactome", "description": "RNA Polymerase II Transcription Initiation" }, { "id": "R-GGA-76042", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-76042", "resource": "Reactome", "description": "RNA Polymerase II Transcription Initiation And Promoter Clearance" } ], "orthologs": [ { "uniprot_canonical_ac": "E1BIA9-1", "protein_name": "Transcription initiation factor TFIID subunit 3", "gene_name": "TAF3", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MCESYSRSLLRVSVAQICQALGWDSVQLSACHLLTDVLQRYLQQLGRGCHRYSELYGRTDPILDDVGEAFQLMGVSLHELEDYIHNIEPVTFPHQIPSFPVSKNNVLQFPQPGSKDAEERKEYIPDYMPPIVSSQEEEEEEQVPTDGGTSAEAMQVPLEEDDELEEEEIINDENFLGKRPLDSPEAEEMPAMKRPRLLSTKGDALDVVLLEAREPLSSLNPQKIPPMLSPVHTQDSTDPAPPSPEPPMLAPVAKSQMPTTKPLEAKSFTPKTKTKTSSPGQKTKSPKMIPSPAMVGSPIRSPKTISKEKKSPGRSKSPKSPKSPKVMTHIPQVPVRPDTPNRTPSATISEKISKETVQVKQIQTLPDAGRLNSESQLRKAVVTDKTIDDSIDAVIARACAEREPDPFEFSSGSESEGDIFTSPKRISGSDSATPKASTSSNNFPKSGSTPLPLSGGTSSSDNSWTMDASIDEVVRKAKMGTPPSMPPSFPYISSPSVSPPTPEPAHKVYEEKPKPPASLDVKKKLKKELKTKMKKKEKQRDKERDRDKSKEKSKEKEKGKEKEKDREATKEAKYPWKDFLKDEEADPYKFKIKEFEDVDPKARLKDGIVRKEKEKHKDKKKDREKGKKDKEKRDKEKVKEKGREEKLKAPPAPLVLPPKDVALPLFSPAAAMRITAVLPSLTPVLPEKLFEEKEKPKEKERKKDKKEKKKKKEKEKEKEKKEKEREKEKREREKREKEKERHKHEKIKVEPVVPAPSPVIPRLTLKVGAGQDKIVISKVVPAPEAKPAPSLNRPKTPPPAPAPAPAAMHVTPAPVPLPLLAPASAPLAGMPAPAPAASGAASSKAPVRSVVTETVSTYVIRDEWGNQIWICPGCNKPDDGSPMIGCDDCDDWYHWPCVGIMAAPPEEMQWFCPKCCNRKKDKKHKKRKHRAH", "length": 932 }, "evidence": [ { "id": "F1NZW0", "url": "https://omabrowser.org/oma/group/F1NZW0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "G3GR60-1", "protein_name": "Transcription initiation factor TFIID subunit 3", "gene_name": "Taf3", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MCESYSRSLLRVSVAQICQALGWDSVQLSACHLLTDVLQRYLQQLGRGCHRYSELYGRTDPILDDVSEAFQLMGVNLHELEDYIHNIEPVTFPHQIPSFPVSKNNVLQFPQPGSKDAEERKDYIPDYLPPIVSSQEEEEEEQVPTDGGTSAEAMQVPLEEDDEMEEEEVINDENFLGKRPLDSPEVEEMPTMKRPRLLSTKGDSLDVVLLEAREPLSSINPQKIPPMLSPVHVQDNTDLAPPSPEPPMLAPFAKSQLPTAKPLETKSFTPKTKTKASSPGQKTKSPKTTLSPARLGSPIRSPKTIPKEKKSPGRSKSPKSPKSPKIITHTPQPPARPETPNRTPSAIVVEKTVKESIPVKPTQTPPEIGKLNMEMQPKKAVVTDKTIDDSIDAVIARACAEREPDPFEFSSGSESEVDTFTSPKRISGSECTTPKASTSSNNFTKSGSTPLPLSGGTSSSDNSWTMDASIDEVVRKAKLGTPSNMPPTFQYISSPSISPPTPEPLHKGYEEKAKLPSSVDVKKKLKKELKTKLKKKEKQRDREREKERNKERSKEKDKMREREKEKESAKEVRYPWKEFMKDEDPDPYKFKIREFEDIDPKVRLKDGIVRKEKEKHKDKKKDRERSKRDKDKREREKIKEKSREDKIKAPPTQLVLPPKEMALPLFSPSAAVRVPSMLPALSPMLPEKLFEEKEKPKEKERKKDKKEKKKKKEKEKEKEKKEREREKEKREREKREKEKEKHKHEKIKVEPVIPAPSPVIPRLTLRVGAGQDKIVISKVVPAPEAKPAPSLNRPKTPPPAPVPVPVRVSPTPLPPPLLAQAAMCPALMPSPAPALSGAGSAKAPVRSVVTETVSTYVIRDEWGNQIWICPGCNKPDDGSPMIGCDGCDDWYHWPCVGLMAAPPEEMQWFCAKCAKIKKDKKHKKRKHRAH", "length": 930 }, "evidence": [ { "id": "F1NZW0", "url": "https://omabrowser.org/oma/group/F1NZW0/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q5HZG4-1", "protein_name": "Transcription initiation factor TFIID subunit 3", "gene_name": "Taf3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MCESYSRSLLRVSVAQICQALGWDSVQLSACHLLTDVLQRYLQQLGRGCHRYSELYGRTDPILDDVGEAFQLMGVNLHELEDYIHNIEPVTFPHQIPSFPVSKNNVLQFPQPGSKDAEERKDYIPDYLPPIVSSQEEEEEEQVPTDGGTSAEAMQVPLEEDDEMEEEEVINDENFLGKRPLDSPEVEEMPSMKRPRLLSTKGDSLDVVLLEAREPLSSINPQKTPPVLSPVRVQDRADLAPPSPQPPMLAPFAKSQLPIAKPLETKSFTPKTKTKASSPGQKTKSPKAALSPARLGSPIRSPKTIPKEKKSPGRSKSPKSPKSPKIVAHVPQTPVRPETPNRTPSAMVVEKTVKETIPVMKPTQTPPEVVKLNIEMQPKKPVVTDKTIDDSIDAVIARACAEREPDPFEFSSGSESEGDTFTSPKRISGSECATPKASTSSNNFTKSLATPLPLSSGTSSSDNSWTMDASIDEVVRKAKLGAPSNMPPTFPYISSPSISPPTPEPLHKGYEEKAKLPSSVDVKKKLKKELKTKLKKKEKQRDRERERERNKERSKEKDKMREREKEKEAGKELKYPWRELMKDEDSDPYKFKIKEFEDIDAAKVRLKDGIVRREREKHKDKKKDRERSKREKDKRERERLKEKNREDKIKAPPTQLVLPPKEMALPLFSPSAVRVPAMLPAFSPMLPEKLFEEKEKPKEKERKKDKKEKKKKKEKEKEKEKKEREREKERREREKREKEKEKHKHEKIKVEPVIPAPSPVIPRLTLRVGAGQDKIVISKVVPAPEAKPAPSLNRPKTPPPAPVPIPVRVSPTPLQPPLLTQAAVCPALMPSPAPALSGIGSAKAPVRSVVTETVSTYVIRDEWGNQIWICPGCNKPDDGSPMIGCDDCDDWYHWPCVGIMAAPPEEMQWFCPKCANKIKKDKKHKKRKHRAH", "length": 932 }, "evidence": [ { "id": "F1NZW0", "url": "https://omabrowser.org/oma/group/F1NZW0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q5RH27-1", "protein_name": "Transcription initiation factor TFIID subunit 3", "gene_name": "taf3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MCESFARSLLRVSVAQMCQAVGWDAVQLSACDLLSDVLERYVQQLAKSCHRYSELYGRTDPGLSDVDQAFGFLGVSIAELEDYVNNVEPIGYPQTIPQFPISKSSVLQFPAAGFDTDARDALRGERRDYIPEYFPPLVSLQEDEEEEEPVPADMGTSAEAMQVSMGEEEDGEEEENDENWLSRHDGQSPRPEGLLPAAKRPRLSTKPGVSPEWSYEPREPLSSLNSQHMPHSPSPPLSPELPRPPVAPPTPGHKPKLPSPSPARQKNKSPKRGGAAPTGVLGRPLTLTPPKTNQKAGKRSPGMPKSPRSPRPSSAPLGIAGRGWPGPLADDSSRDGQFKCNDTDDKDIENSIAAVIARACAGEDGTSDPFAYDSDSDSEGPHPPKPVPKHTLSHIKPPQALTSKHLLPPVPPLLNPPIRWTMDDSIDEVIRKASQGQKPIQPPSLSPLEPPYLSSPSDSPPTPPPPLKLTQERKDSPTGNLLKKKLKKDIKTKLKKKDKERLKEKGKEKGKNKEKNKEKKREKERGQVEENKMPWPELSLVVGGEERRDGIGGKKEKDKHKDKKKDKEKGKKEKEKRDKGKERGKEEKRISQGTKDIAIAVAGATSPLFSPQTCLRIPSMLPPLPPILPDKLFPHPKDIKSKDKDKKKDKKEKKKKKEKEKDREKEREKEREKERTKEKERDKEEKKKDKEKKEKTKEKEKDKPKLEKTSLMAEIPPAVPPSPVIPRLTLRVGAGQDKIVISKVVPDTEPTPPPPRTPVARMGPGARIRPPPVLPPPAPPPATPPPRPPPVLPPPPPPAAPIQTPPNQAKARGCSVVTETVSAYVIRDEWGNQIWICPGCNKADDGSPMIGCDECDDWYHWPCVGLLAAPPEDQSWFCIKCAGKKKDKKTKKRKRKAH", "length": 898 }, "evidence": [ { "id": "F1NZW0", "url": "https://omabrowser.org/oma/group/F1NZW0/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q5VWG9-1", "protein_name": "Transcription initiation factor TFIID subunit 3", "gene_name": "TAF3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MCESYSRSLLRVSVAQICQALGWDSVQLSACHLLTDVLQRYLQQLGRGCHRYSELYGRTDPILDDVGEAFQLMGVSLHELEDYIHNIEPVTFPHQIPSFPVSKNNVLQFPQPGSKDAEERKEYIPDYLPPIVSSQEEEEEEQVPTDGGTSAEAMQVPLEEDDELEEEEIINDENFLGKRPLDSPEAEELPAMKRPRLLSTKGDTLDVVLLEAREPLSSINTQKIPPMLSPVHVQDSTDLAPPSPEPPMLAPVAKSQMPTAKPLETKSFTPKTKTKTSSPGQKTKSPKTAQSPAMVGSPIRSPKTVSKEKKSPGRSKSPKSPKSPKVTTHIPQTPVRPETPNRTPSATLSEKISKETIQVKQIQTPPDAGKLNSENQPKKAVVADKTIEASIDAVIARACAEREPDPFEFSSGSESEGDIFTSPKRISGPECTTPKASTSANNFTKSGSTPLPLSGGTSSSDNSWTMDASIDEVVRKAKLGTPSNMPPNFPYISSPSVSPPTPEPLHKVYEEKTKLPSSVEVKKKLKKELKTKMKKKEKQRDREREKDKNKDKSKEKDKVKEKEKDKETGRETKYPWKEFLKEEEADPYKFKIKEFEDVDPKVKLKDGLVRKEKEKHKDKKKDREKGKKDKDKREKEKVKDKGREDKMKAPAPPLVLPPKELALPLFSPATASRVPAMLPSLLPVLPEKLFEEKEKVKEKEKKKDKKEKKKKKEKEKEKKEKEREKEKREREKREKEKEKHKHEKIKVEPVALAPSPVIPRLTLRVGAGQDKIVISKVVPAPEAKPAPSQNRPKTPPPAPAPAPGPMLVSPAPVPLPLLAQAAAGPALLPSPGPAASGASAKAPVRSVVTETVSTYVIRDEWGNQIWICPGCNKPDDGSPMIGCDDCDDWYHWPCVGIMTAPPEEMQWFCPKCANKKKDKKHKKRKHRAH", "length": 929 }, "evidence": [ { "id": "F1NZW0", "url": "https://omabrowser.org/oma/group/F1NZW0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 8, "go_terms": [ { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "F1NZW0", "url": "https://www.uniprot.org/uniprotkb/F1NZW0" } ], "pmid": "" }, { "name": "transcription by RNA polymerase II", "id": "GO:0006366", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006366", "evidence": [ { "database": "UniProtKB", "id": "F1NZW0", "url": "https://www.uniprot.org/uniprotkb/F1NZW0" } ], "pmid": "" }, { "name": "negative regulation of signal transduction by p53 class mediator", "id": "GO:1901797", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901797", "evidence": [ { "database": "UniProtKB", "id": "F1NZW0", "url": "https://www.uniprot.org/uniprotkb/F1NZW0" } ], "pmid": "" }, { "name": "positive regulation of transcription initiation by RNA polymerase II", "id": "GO:0060261", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060261", "evidence": [ { "database": "UniProtKB", "id": "F1NZW0", "url": "https://www.uniprot.org/uniprotkb/F1NZW0" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "F1NZW0", "url": "https://www.uniprot.org/uniprotkb/F1NZW0" } ], "pmid": "" }, { "name": "mRNA transcription by RNA polymerase II", "id": "GO:0042789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042789", "evidence": [ { "database": "UniProtKB", "id": "F1NZW0", "url": "https://www.uniprot.org/uniprotkb/F1NZW0" } ], "pmid": "" }, { "name": "maintenance of protein location in nucleus", "id": "GO:0051457", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051457", "evidence": [ { "database": "UniProtKB", "id": "F1NZW0", "url": "https://www.uniprot.org/uniprotkb/F1NZW0" } ], "pmid": "" }, { "name": "RNA polymerase II preinitiation complex assembly", "id": "GO:0051123", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051123", "evidence": [ { "database": "UniProtKB", "id": "F1NZW0", "url": "https://www.uniprot.org/uniprotkb/F1NZW0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1NZW0", "url": "https://www.uniprot.org/uniprotkb/F1NZW0" } ], "pmid": "" }, { "name": "nuclear membrane", "id": "GO:0031965", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031965", "evidence": [ { "database": "UniProtKB", "id": "F1NZW0", "url": "https://www.uniprot.org/uniprotkb/F1NZW0" } ], "pmid": "" }, { "name": "transcription factor TFIID complex", "id": "GO:0005669", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005669", "evidence": [ { "database": "UniProtKB", "id": "F1NZW0", "url": "https://www.uniprot.org/uniprotkb/F1NZW0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "F1NZW0", "url": "https://www.uniprot.org/uniprotkb/F1NZW0" } ], "pmid": "" }, { "name": "protein heterodimerization activity", "id": "GO:0046982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046982", "evidence": [ { "database": "UniProtKB", "id": "F1NZW0", "url": "https://www.uniprot.org/uniprotkb/F1NZW0" } ], "pmid": "" }, { "name": "transcription regulator inhibitor activity", "id": "GO:0140416", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140416", "evidence": [ { "database": "UniProtKB", "id": "F1NZW0", "url": "https://www.uniprot.org/uniprotkb/F1NZW0" } ], "pmid": "" }, { "name": "p53 binding", "id": "GO:0002039", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002039", "evidence": [ { "database": "UniProtKB", "id": "F1NZW0", "url": "https://www.uniprot.org/uniprotkb/F1NZW0" } ], "pmid": "" }, { "name": "histone H3K4me3 reader activity", "id": "GO:0140002", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140002", "evidence": [ { "database": "UniProtKB", "id": "F1NZW0", "url": "https://www.uniprot.org/uniprotkb/F1NZW0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 375, "end_pos": 377, "annotation": "n_glycosylation_sequon" }, { "start_pos": 443, "end_pos": 445, "annotation": "n_glycosylation_sequon" }, { "start_pos": 490, "end_pos": 492, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1NZW0-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 930, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1NZW0-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1NZW0" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1NZW0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NZW0" }, { "id": "PS50016", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50016" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PHD-type", "eco_id": "ECO_0000259", "start_pos": 866, "end_pos": 916, "start_aa": "Ile", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 503, 809, 822 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 375, "end_pos": 377 }, { "start_pos": 443, "end_pos": 445 }, { "start_pos": 490, "end_pos": 492 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 3 }, { "field": "total_sites", "count": 3 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 3 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 3 }, { "field": "exact_o_linked_sites", "count": 3 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 3 }, { "field": "total_sites", "count": 3 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 3 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 3 }, { "field": "exact_o_linked_sites", "count": 3 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1NNM2-1", "uniprot_ac": "F1NNM2", "uniprot_id": "F1NNM2_CHICK", "mass": { "chemical_mass": 19997.0, "monoisotopic_mass": 19997.0 }, "refseq": {}, "gene_names": [ { "name": "GABARAPL2", "type": "recommended", "evidence": [ { "id": "F1NNM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NNM2" } ] } ], "protein_names": [ { "name": "Gamma-aminobutyric acid receptor-associated protein-like 2", "type": "recommended", "evidence": [ { "id": "F1NNM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NNM2/entry#names_and_taxonomy" } ] }, { "name": "GABA(A) receptor-associated protein-like 2", "type": "synonym", "evidence": [ { "id": "F1NNM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NNM2/entry#names_and_taxonomy" } ] }, { "name": "Golgi-associated ATPase enhancer of 16 kDa", "type": "synonym", "evidence": [ { "id": "F1NNM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NNM2/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Ubiquitin-like modifier involved in intra-Golgi traffic. Modulates intra-Golgi transport through coupling between NSF activity and SNAREs activation. It first stimulates the ATPase activity of NSF which in turn stimulates the association with GOSR1. Involved in autophagy. Plays a role in mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Whereas LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation.", "evidence": [ { "database": "UniProtKB", "id": "F1NNM2", "url": "https://www.uniprot.org/uniprotkb/F1NNM2#function" }, { "database": "UniProtKB", "id": "ARBA00056137", "url": "https://www.uniprot.org/uniprotkb/ARBA00056137#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NNM2", "url": "https://www.uniprot.org/uniprotkb/F1NNM2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "GABARAPL2", "url": "https://www.uniprot.org/uniprotkb/F1NNM2", "locus": { "chromosome": "11", "start_pos": 19545466, "end_pos": 19560037, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010008905", "url": "https://www.ensembl.org/id/ENSGALG00010008905" } ] } } ], "crossref": [ { "id": "F1NNM2", "url": "https://alphafold.ebi.ac.uk/entry/F1NNM2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000003208", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000003208", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd17163", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd17163", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR004241", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004241", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029071", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029071", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XV39", "url": "https://www.orthodb.org/?gene=A0A8V0XV39", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y7Y9", "url": "https://www.orthodb.org/?gene=A0A8V0Y7Y9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NNM2", "url": "https://www.orthodb.org/?gene=F1NNM2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10969", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10969", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02991", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02991", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-1632852", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1632852", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0XV39", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XV39", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XV39-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XV39-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": 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"MKWMFKEDHALEHRCVESAKIRAKYPDRVPVIVEKVSGSQIVDIDKRKYLVPSDITVAQFMWIIRKRIQLPSEKAIFLFVDKTVPQSRSIRNALFLSSQYCRTARNKQEKKRKKGTLYHLTQ", "length": 122, "header": "tr|A0A8V0Y7Y9-1|A0A8V0Y7Y9_CHICK Computationally mapped isoform of GABA type A receptor associated protein like 2 OS=Gallus gallus OX=9031 GN=GABARAPL2 PE=1 SV=1 CANONICAL=F1NNM2-1" }, "locus": { "chromosome": "11", "start_pos": 19559229, "end_pos": 19553550, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010021129.1", "url": "https://www.ensembl.org/id/ENSGALT00010021129.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010012104.1", "url": "https://www.ensembl.org/id/ENSGALP00010012104.1" } ] } }, { "isoform_ac": "F1NNM2-1", "url": "https://www.uniprot.org/uniprotkb/F1NNM2/entry#F1NNM2-1", "sequence": { "sequence": "MPGSYPGQGRWWPRKAARTGTGPWAALGTRSASARNLRAETARGLNAAPGRAPRGWELLTVAPVGHQQRRHVEHRCVESAKIRAKYPDRVPVIVEKVSGSQIVDIDKRKYLVPSDITVAQFMWIIRKRIQLPSEKAIFLFVDKTVPQSSLTMGQLYEKEKDEDGFLYVAYSGENTFGF", "length": 178, "header": "tr|F1NNM2-1|F1NNM2_CHICK Isoform 1 of Gamma-aminobutyric acid receptor-associated protein-like 2 OS=Gallus gallus OX=9031 GN=GABARAPL2 PE=1 SV=4 CANONICAL=F1NNM2-1" }, "locus": { "chromosome": "11", "start_pos": 19560024, "end_pos": 19552295, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010021133.1", "url": "https://www.ensembl.org/id/ENSGALT00010021133.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010012106.1", "url": "https://www.ensembl.org/id/ENSGALP00010012106.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-1632852", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1632852", "resource": "Reactome", "description": "Macroautophagy" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": 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"evidence": [ { "database": "UniProtKB", "id": "F1NNM2", "url": "https://www.uniprot.org/uniprotkb/F1NNM2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "autophagy", "id": "GO:0006914", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006914", "evidence": [ { "database": "UniProtKB", "id": "F1NNM2", "url": "https://www.uniprot.org/uniprotkb/F1NNM2" } ], "pmid": "" }, { "name": "autophagosome maturation", "id": "GO:0097352", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097352", "evidence": [ { "database": "UniProtKB", "id": "F1NNM2", "url": "https://www.uniprot.org/uniprotkb/F1NNM2" } ], "pmid": "" }, { "name": "autophagosome assembly", "id": "GO:0000045", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000045", "evidence": [ { "database": "UniProtKB", "id": "F1NNM2", "url": "https://www.uniprot.org/uniprotkb/F1NNM2" } ], "pmid": "" }, { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", 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"table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1NPI1-1", "uniprot_ac": "F1NPI1", "uniprot_id": "F1NPI1_CHICK", "mass": { "chemical_mass": 71686.0, "monoisotopic_mass": 71686.0 }, "refseq": { "ac": "XP_419056", "name": "sodium-dependent neutral amino acid transporter B(0)AT1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_419056" }, "gene_names": [ { "name": "SLC6A19", "type": "recommended", "evidence": [ { "id": "F1NPI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NPI1" } ] }, { "name": "SLC6A19", "type": "synonym", "evidence": [ { "id": "XP_419056", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_419056" } ] } ], "protein_names": [ { "name": "Transporter", "type": "recommended", "evidence": [ { "id": "F1NPI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NPI1/entry#names_and_taxonomy" } ] }, { "name": "sodium-dependent neutral amino acid transporter B(0)AT1", "type": "synonym", "evidence": [ { "id": "XP_419056", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_419056" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052533.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_419056", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_419056" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NPI1", "url": "https://www.uniprot.org/uniprotkb/F1NPI1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SLC6A19", "url": "https://www.uniprot.org/uniprotkb/F1NPI1", "locus": { "chromosome": "2", "start_pos": 85332213, "end_pos": 85310809, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010009209", "url": "https://www.ensembl.org/id/ENSGALG00010009209" } ] } } ], "crossref": [ { "id": "F1NPI1", "url": "https://alphafold.ebi.ac.uk/entry/F1NPI1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000019527", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000019527", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd11516", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11516", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "420971", "url": "https://www.ncbi.nlm.nih.gov/gene/420971", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000175", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000175", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037272", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037272", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:420971", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420971", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WPKELIT", "url": "https://omabrowser.org/oma/group/WPKELIT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y501", "url": "https://www.orthodb.org/?gene=A0A8V0Y501", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NPI1", "url": "https://www.orthodb.org/?gene=F1NPI1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11616", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11616", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11616:SF125", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11616:SF125", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00209", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00209", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-352230", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-352230", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-442660", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-442660", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_419056", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_419056", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Y501", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y501", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y501-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y501-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NPI1", "url": "https://www.uniprot.org/uniprotkb/F1NPI1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NPI1-1", "url": "https://www.uniprot.org/uniprotkb/F1NPI1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVKLQLPNPGLEDRIPSHTELEVLEKEEADSRPKWDNKAQYMLTCVGFCVGLGNVWRFPYLCQSHGGGAFMIPFLILLILEGIPLLHLEFAIGQRLRRGSVGVWSSIHPTLKGVGIAAMCVSFLVSLYYNTIIAWVMWYFFNSFQEPLPWSTCPLIDNRTDYIEECAKSSPVDYFWYRETLNTSTSIEDSGTIQWWLLLCLTCAWGILYVCTIRGIETTGKAVYITSTLPYLVLTIFLIRGLTLKGSVNGIVFLFTPNVAELANPVTWLDAGAQVFYSFSLAFGGLISFSSYNPVHNNCEKDAVIISVINGFTSIYAATVIYSIIGFRATERYDDCFDKNILTLINAFDLPEGNVTQDNFEQMQQLCNMTDPVTFASLNFETCDLKSFLSEGVEGTGLAFIVFTEAITKMPVSPLWSILFFIMLFCLGLSSMFGNVEGVLVPLQDLKVVPPKWPKELITGIVCAGSYLIAFIFVLRSGNYWLALFDSFAGSIPLLIIAFCEMFSVVYIYGIDRFNKDIEFMIGHKPNIFWQVTWRVISPLIMLVIFLFYFVVKVNEELLYSVWNPKYEEFPKPQKIGYPGWVYAIIVIIAGVPSLIIPVFAIYKAIRNCCQKRRDRTGLISSISETSVNGNLKNSA", "length": 636, "header": "tr|F1NPI1-1|F1NPI1_CHICK Isoform 1 of Transporter OS=Gallus gallus OX=9031 GN=SLC6A19 PE=3 SV=2 CANONICAL=F1NPI1-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Y501-1", "url": "https://www.uniprot.org/uniprotkb/F1NPI1/entry#A0A8V0Y501-1", "sequence": { "sequence": "MGQQGSVYADMRRVLCWLRKRVALSVSLPEPWRRSLHDPFPDFVDSGGSIHPTLKGVGIAAMCVSFLVSLYYNTIIAWVMWYFFNSFQEPLPWSTCPLIDNRTDYIEECAKSSPVDYFWYRETLNTSTSIEDSGTIQWWLLLCLTCAWGILYVCTIRGIETTGKAVYITSTLPYLVLTIFLIRGLTLKGSVNGIVFLFTPNVAELANPVTWLDAGAQVFYSFSLAFGGLISFSSYNPVHNNCEKDAVIISVINGFTSIYAATVIYSIIGFRATERYDDCFDKNILTLINAFDLPEGNVTQDNFEQMQQLCNMTDPVTFASLNFETCDLKSFLSEGVEGTGLAFIVFTEAITKMPVSPLWSILFFIMLFCLGLSSMFGNVEGVLVPLQDLKVVPPKWPKELITGIVCAGSYLIAFIFVLRSGNYWLALFDSFAGSIPLLIIAFCEMFSVVYIYGIDRFNKDIEFMIGHKPNIFWQVTWRVISPLIMLVIFLFYFVVKVNEELLYSVWNPKYEEFPKPQKIGYPGWVYAIIVIIAGVPSLIIPVFAIYKAIRNCCQKRRDRTGLISSISETSVNGNLKNSA", "length": 579, "header": "tr|A0A8V0Y501-1|A0A8V0Y501_CHICK Computationally mapped isoform of Solute carrier family 6 member 19 OS=Gallus gallus OX=9031 GN=SLC6A19 PE=4 SV=1 CANONICAL=F1NPI1-1" }, "locus": { "chromosome": "2", "start_pos": 85331253, "end_pos": 85311007, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010021967.1", "url": "https://www.ensembl.org/id/ENSGALT00010021967.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010012582.1", "url": "https://www.ensembl.org/id/ENSGALP00010012582.1" } ] } }, { "isoform_ac": "F1NPI1-1", "url": "https://www.uniprot.org/uniprotkb/F1NPI1/entry#F1NPI1-1", "sequence": { "sequence": "MVKLQLPNPGLEDRIPSHTELEVLEKEEADSRPKWDNKAQYMLTCVGFCVGLGNVWRFPYLCQSHGGGAFMIPFLILLILEGIPLLHLEFAIGQRLRRGSVGVWSSIHPTLKGVGIAAMCVSFLVSLYYNTIIAWVMWYFFNSFQEPLPWSTCPLIDNRTDYIEECAKSSPVDYFWYRETLNTSTSIEDSGTIQWWLLLCLTCAWGILYVCTIRGIETTGKAVYITSTLPYLVLTIFLIRGLTLKGSVNGIVFLFTPNVAELANPVTWLDAGAQVFYSFSLAFGGLISFSSYNPVHNNCEKDAVIISVINGFTSIYAATVIYSIIGFRATERYDDCFDKNILTLINAFDLPEGNVTQDNFEQMQQLCNMTDPVTFASLNFETCDLKSFLSEGVEGTGLAFIVFTEAITKMPVSPLWSILFFIMLFCLGLSSMFGNVEGVLVPLQDLKVVPPKWPKELITGIVCAGSYLIAFIFVLRSGNYWLALFDSFAGSIPLLIIAFCEMFSVVYIYGIDRFNKDIEFMIGHKPNIFWQVTWRVISPLIMLVIFLFYFVVKVNEELLYSVWNPKYEEFPKPQKIGYPGWVYAIIVIIAGVPSLIIPVFAIYKAIRNCCQKRRDRTGLISSISETSVNGNLKNSA", "length": 636, "header": "tr|F1NPI1-1|F1NPI1_CHICK Isoform 1 of Transporter OS=Gallus gallus OX=9031 GN=SLC6A19 PE=3 SV=2 CANONICAL=F1NPI1-1" }, "locus": { "chromosome": "2", "start_pos": 85331253, "end_pos": 85310906, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010021974.1", "url": "https://www.ensembl.org/id/ENSGALT00010021974.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010012587.1", "url": "https://www.ensembl.org/id/ENSGALP00010012587.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:420971", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420971", "resource": "KEGG Pathway" }, { "id": "R-GGA-352230", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-352230", "resource": "Reactome", "description": "Amino acid transport across the plasma membrane" }, { "id": "R-GGA-442660", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-442660", "resource": "Reactome", "description": "SLC-mediated transport of neurotransmitters" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2LWZ8-1", "protein_name": "Transporter", "gene_name": "Slc6a19", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MVRLVLPNPGLEDRIPSRDELEVIEKEEASSRPKWDNKAQYMLTCVGFCVGLGNVWRFPYLCQSHGGGAFMIPFLILLVLEGIPLLHLEFAIGQRLRKGSVGVWSSIHPALKGVGIASMFVSFMVGLYYNTIIAWVMWYFFNSFQEPLPWSECPLNVNQTGYVEECAKSSSVDYFWYRETLNISTSISDSGSIQWWILLCLTCAWSVLYVCVIRGIETTGKAVYVTSTLPYVVLTIFLIRGLTLKGATNGIVFLFTPNITELSNPNTWLDAGAQVFYSFSLAFGGLISFSSYNSVHNNCEMDSVIVSIINGFTSVYAATVVYSIIGFRATERFDDCVNTNILTLINGFDLPEGNVTSENFEAVQQWCNATNPEVYAQLKFQTCDMNSFLSEGVEGTGLAFIVFTEAITKMPVSPLWSVLFFIMLFCLGLSSMFGNMEGVVVPLQDLNLIPKKWPKELMTGLICLGTYLIAFIFTLNSGQYWLSLLDSYAGSIPLLIIAFCEMFAVVYVYGVDRFNKDIEFMIGHKPNIFWQVTWRVVSPLIMLVIFLFFFVIEVNKKLMYSVWDPNYEEFPKSQRVPYPNWVYAVVVIVAGVPCLTIPCFAIYKLIRNRCQKSGDHHGLVNALSTASVNGDLKY", "length": 634 }, "evidence": [ { "id": "F1NPI1", "url": "https://omabrowser.org/oma/group/F1NPI1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "E7EY30-1", "protein_name": "Transporter", "gene_name": "slc6a19a.2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MKLKLKLPNPGLEQRIPSHSELEKLELQEAGERPKWDNKAQYMLTCVGFCVGLGNVWRFPYLCQSHGGGAFMIPFLILLVLEGIPLLHLEFAIGQRLRRGSVGVWRSINPYLLGVGIASMLVSFIVGMYYNTIIAWVMWYFFNSFQDPLPWSQCPINGSRTGFVSECERSSPVDYFWYRKTLNTTPHIEDSGGLQWWMVLSLLCAWTVLWVCCIRGIETTGKAVYITSTLPYLVLTIFLIRGLTLKGSVSGIKFLFTPDVNELLDPQTWLDAGAQVFFSFSLAFGGLIAFSSYNSVHNNCEQDAVIISIINGMTSIYAAIVIYSIIGFRATERFDDCLNGNILSLLNAFDLPEGSIIEGNYTEAIQQLNISRPDIIQELQLKTCDMQTFLSQGVEGTGLAFIVFTEAITKMPVSPLWSVLFFIMLFCLGLSTMFGSIEGVVVPLQDLDILPKNWPKEAYTALVCVVSFAFAIIFAQGSGEYWLALFDGFAVSIPLLIIAFCEMMAVSYVYGIDRFNDDIKFMIGHKPNIFWQATWRLISPLIVLVIFLFYFVTTVSKKLTYIAWDPESENFPTLSVLPYPGWISAIIFILAGIPVLVIPTVALVRLIRNRCCKKEETHATETPYSISDRVQMMEETEQNNPISTALH", "length": 647 }, "evidence": [ { "id": "F1NPI1", "url": "https://omabrowser.org/oma/group/F1NPI1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "G5E6L1-1", "protein_name": "Transporter", "gene_name": "SLC6A19", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MVRLALPNPGLEARIPSLGELERVEREESSSRPTWDNKAQYMLTCVGFCVGLGNVWRFPYLCQSHGGGAFMIPFLILLVLEGIPLLHLEFAIGQRLRKGSVGVWSAIHPALKGVGIASMFVSFMVGLYYNTIIAWVMWYFFNSFQEPLPWSQCPLNANQTGYVDECARSSSVDYFWYRETLNVSTSIDDSGSVQWWILLALTCAWSVLYVCTIRGIETTGKAVYITSTLPYVVLTIFLIRGLTLKGATNGIVFLFTPNVTELANPVTWLDAGAQVFYSFSLAFGGLISFSSYNPVHNNCEMDSVIVSVINGFTSVYAATVVYSIIGFRATERYDDCFSTNILTLINGFDLPEGNVTQENFAEMQRWCNASDPAAYARLKFQTCDMDAFLSQGVEGTGLAFIVFTEAITKMPVAPLWSVLFFVMLFCLGLSSMFGNMEGVVVPLQDLKVIPKKWPKELLTGLICLGMYLIAFIFTLNSGQYWLSLLDSYAGSIPLLVIAFFEMFSVVYVYGVDRFNRDIEFMIGHKPNIFWQVTWRVVSPLLMLAIFLFFFVIEVREELTYNIWDPAYEEFPKSKEIKYPGWVYAVVVLVAGVPCLVIPGFAIYKLIRNHFQRRGDQRALVSSLSAASVNGGLWS", "length": 634 }, "evidence": [ { "id": "F1NPI1", "url": "https://omabrowser.org/oma/group/F1NPI1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q2A865-1", "protein_name": "Sodium-dependent neutral amino acid transporter B(0)AT1", "gene_name": "Slc6a19", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVRLVLPNPGLEDRIPSLDELEVIEKEEASSRPKWDNKAQYMLTCVGFCVGLGNVWRFPYLCQSHGGGAFMIPFLILLVLEGIPLLHLEFAIGQRLRKGSVGVWSSIHPALKGVGIASMFVSFMVGLYYNTIIAWVMWYFFNSFQEPLPWSECPLNQNQTGYVEECAKSSSVDYFWYRETLNISTSISDSGSIQWWILLCLTCAWSVLYVCTIRGIETTGKAVYITSTLPYVVLTIFLIRGLTLKGATNGIVFLFTPNITELSNPNTWLDAGAQVFYSFSLAFGGLISFSSYNSVHNNCEMDSVIVSIINGFTSVYAATVVYSIIGFRATERFDDCVNTNILTLINGFDLPEGNVTAENFEAYQHWCNATNPEAYAQLTFQTCDINTFLSEGVEGTGLAFIVFTEAITKMPVSPLWSVLFFIMLFCLGLSSMFGNMEGVVVPLQDLNITPKKWPKELLTGLICLGTYLIAFIFTLNSGQYWLSLLDSYAGSIPLLIIAFCEMFAVVYVYGVDRFNKDIEFMIGHKPNIFWQVTWRVVSPLIMLVIFLFFFVIEVNKQLMYSVWDPDYEEFPKSQKVPYPDWVYAVVVIVAGVPCLTIPCFAIYKLIRNYCQKSGDQHGLVNALSTASVNGDLKN", "length": 634 }, "evidence": [ { "id": "F1NPI1", "url": "https://omabrowser.org/oma/group/F1NPI1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q695T7-1", "protein_name": "Sodium-dependent neutral amino acid transporter B(0)AT1", "gene_name": "SLC6A19", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVRLVLPNPGLDARIPSLAELETIEQEEASSRPKWDNKAQYMLTCLGFCVGLGNVWRFPYLCQSHGGGAFMIPFLILLVLEGIPLLYLEFAIGQRLRRGSLGVWSSIHPALKGLGLASMLTSFMVGLYYNTIISWIMWYLFNSFQEPLPWSDCPLNENQTGYVDECARSSPVDYFWYRETLNISTSISDSGSIQWWMLLCLACAWSVLYMCTIRGIETTGKAVYITSTLPYVVLTIFLIRGLTLKGATNGIVFLFTPNVTELAQPDTWLDAGAQVFFSFSLAFGGLISFSSYNSVHNNCEKDSVIVSIINGFTSVYVAIVVYSVIGFRATQRYDDCFSTNILTLINGFDLPEGNVTQENFVDMQQRCNASDPAAYAQLVFQTCDINAFLSEAVEGTGLAFIVFTEAITKMPLSPLWSVLFFIMLFCLGLSSMFGNMEGVVVPLQDLRVIPPKWPKEVLTGLICLGTFLIGFIFTLNSGQYWLSLLDSYAGSIPLLIIAFCEMFSVVYVYGVDRFNKDIEFMIGHKPNIFWQVTWRVVSPLLMLIIFLFFFVVEVSQELTYSIWDPGYEEFPKSQKISYPNWVYVVVVIVAGVPSLTIPGYAIYKLIRNHCQKPGDHQGLVSTLSTASMNGDLKY", "length": 634 }, "evidence": [ { "id": "F1NPI1", "url": "https://omabrowser.org/oma/group/F1NPI1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9D687-1", "protein_name": "Sodium-dependent neutral amino acid transporter B(0)AT1", "gene_name": "Slc6a19", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVRLVLPNPGLEERIPSLDELEVIEKEEAGSRPKWDNKAQYMLTCVGFCVGLGNVWRFPYLCQSHGGGAFMIPFLILLVFEGIPLLYLEFAIGQRLRKGSMGVWSSIHPALKGIGIASMFVSFMVGLYYNTIIAWVMWYFFNSFQEPLPWSECPLNQNQTGYVEECAKSSSVDYFWYRETLNISTSISDSGSIQWWILLCLTCAWSVLYVCIIRGIETTGKAVYITSTLPYVVLTIFLIRGLTLKGATNGIVFLFTPNITELSNPNTWLDAGAQVFYSFSLAFGGLISFSSYNSVHNNCEMDSVIVSVINGFTSVYAATVVYSIIGFRATERFDDCVNTNILTLINGFDLPEGNVTSENFEAYQQWCNATNPQAYAQLKFQTCDINSFLSEGVEGTGLAFIVFTEAITKMPVSPLWSVLFFIMLFCLGLSSMFGNMEGVVVPLQDLNITPKKWPKELLTGLICLGTYLIAFIFTLNSGQYWLSLLDSFAGSIPLLIIAFCEMFAVVYVYGVDRFNKDIEFMIGHKPNIFWQVTWRVVSPLIMLVIFLFFFVIEVNKTLMYSIWDPNYEEFPKSQKIPYPNWVYAVVVTVAGVPCLSIPCFAIYKFIRNCCQKSDDHHGLVNTLSTASVNGDLKN", "length": 634 }, "evidence": [ { "id": "F1NPI1", "url": "https://omabrowser.org/oma/group/F1NPI1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "F1NPI1", "url": "https://www.uniprot.org/uniprotkb/F1NPI1" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F1NPI1", "url": "https://www.uniprot.org/uniprotkb/F1NPI1" } ], "pmid": "" }, { "name": "brush border membrane", "id": "GO:0031526", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031526", "evidence": [ { "database": "UniProtKB", "id": "F1NPI1", "url": "https://www.uniprot.org/uniprotkb/F1NPI1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "F1NPI1", "url": "https://www.uniprot.org/uniprotkb/F1NPI1" } ], "pmid": "" }, { "name": "neutral L-amino acid transmembrane transporter activity", "id": "GO:0015175", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015175", "evidence": [ { "database": "UniProtKB", "id": "F1NPI1", "url": "https://www.uniprot.org/uniprotkb/F1NPI1" } ], "pmid": "" }, { "name": "symporter activity", "id": "GO:0015293", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015293", "evidence": [ { "database": "UniProtKB", "id": "F1NPI1", "url": "https://www.uniprot.org/uniprotkb/F1NPI1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "neutral amino acid transport", "id": "GO:0015804", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015804", "evidence": [ { "database": "UniProtKB", "id": "F1NPI1", "url": "https://www.uniprot.org/uniprotkb/F1NPI1" } ], "pmid": "" }, { "name": "sodium ion transmembrane transport", "id": "GO:0035725", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035725", "evidence": [ { "database": "UniProtKB", "id": "F1NPI1", "url": "https://www.uniprot.org/uniprotkb/F1NPI1" } ], "pmid": "" }, { "name": "amino acid import across plasma membrane", "id": "GO:0089718", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0089718", "evidence": [ { "database": "UniProtKB", "id": "F1NPI1", "url": "https://www.uniprot.org/uniprotkb/F1NPI1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 158, "end_pos": 160, "annotation": "n_glycosylation_sequon" }, { "start_pos": 182, "end_pos": 184, "annotation": "n_glycosylation_sequon" }, { "start_pos": 354, "end_pos": 356, "annotation": "n_glycosylation_sequon" }, { "start_pos": 368, "end_pos": 370, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1NPI1-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 636, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1NPI1-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1NPI1" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 158, "end_pos": 160 }, { "start_pos": 182, "end_pos": 184 }, { "start_pos": 354, "end_pos": 356 }, { "start_pos": 368, "end_pos": 370 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": 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"count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1NQ92-1", "uniprot_ac": "F1NQ92", "uniprot_id": "F1NQ92_CHICK", "mass": { "chemical_mass": 35769.0, "monoisotopic_mass": 35769.0 }, "refseq": { "ac": "XP_015137811", "name": "regulation of nuclear pre-mRNA domain-containing protein 1A isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015137811" }, "gene_names": [ { "name": "RPRD1A", "type": "recommended", "evidence": [ { "id": "F1NQ92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NQ92" } ] }, { "name": "P15RS", "type": "synonym", "evidence": [ { "id": "XP_015137811", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015137811" } ] }, { "name": "RPRD1A", "type": "synonym", "evidence": [ { "id": "XP_015137811", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015137811" } ] } ], "protein_names": [ { "name": "Regulation of nuclear pre-mRNA domain-containing protein 1A", "type": "recommended", "evidence": [ { "id": "F1NQ92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NQ92/entry#names_and_taxonomy" } ] }, { "name": "Cyclin-dependent kinase inhibitor 2B-related protein", "type": "synonym", "evidence": [ { "id": "F1NQ92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NQ92/entry#names_and_taxonomy" } ] }, { "name": "p15INK4B-related protein", "type": "synonym", "evidence": [ { "id": "F1NQ92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NQ92/entry#names_and_taxonomy" } ] }, { "name": "regulation of nuclear pre-mRNA domain-containing protein 1A isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015137811", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015137811" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052533.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015137811", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015137811" } ] }, { "annotation": "Interacts with phosphorylated C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit POLR2A, and participates in dephosphorylation of the CTD by RPAP2. May act as a negative regulator of cyclin-D1 (CCND1) and cyclin-E (CCNE1) in the cell cycle.", "evidence": [ { "database": "UniProtKB", "id": "F1NQ92", "url": "https://www.uniprot.org/uniprotkb/F1NQ92#function" }, { "database": "UniProtKB", "id": "ARBA00035622", "url": "https://www.uniprot.org/uniprotkb/ARBA00035622#function" }, { "database": "UniProtKB", "id": "A0A8V0XZW8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XZW8#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NQ92", "url": "https://www.uniprot.org/uniprotkb/F1NQ92" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RPRD1A", "url": "https://www.uniprot.org/uniprotkb/F1NQ92", "locus": { "chromosome": "2", "start_pos": 83186958, "end_pos": 83135728, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010008366", "url": "https://www.ensembl.org/id/ENSGALG00010008366" } ] } } ], "crossref": [ { "id": "F1NQ92", "url": "https://alphafold.ebi.ac.uk/entry/F1NQ92", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000013129", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000013129", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd17011", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd17011", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "420953", "url": "https://www.ncbi.nlm.nih.gov/gene/420953", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006569", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006569", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008942", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008942", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032337", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032337", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047884", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047884", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "LWMQRLK", "url": "https://omabrowser.org/oma/group/LWMQRLK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XZW8", "url": "https://www.orthodb.org/?gene=A0A8V0XZW8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y6C6", "url": "https://www.orthodb.org/?gene=A0A8V0Y6C6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NQ92", "url": "https://www.orthodb.org/?gene=F1NQ92", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12460", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12460", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12460:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12460:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04818", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04818", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16566", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16566", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-6807505", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6807505", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_015137811", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015137811", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0XZW8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XZW8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XZW8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XZW8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y6C6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y6C6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y6C6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y6C6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NQ92", "url": "https://www.uniprot.org/uniprotkb/F1NQ92", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NQ92-1", "url": "https://www.uniprot.org/uniprotkb/F1NQ92-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSAFSEAALERKLSELSNSQQSVQTLSLWLIHHRKHSALIVSVWERELRKAKPNRKLTFLYLANDVIQNSKRKGPEFTKDFAPVIVEAFKHVSSESDESCKKHLGRVLSIWEERSVYENDVLEQLRQALYGDRKVKKRTYEQIKVDENNCSPRSSPTDPPQTMDLIRALQELENAASGDAAVHQRIASLPIEVQDVSLLDRITDKESGEQLSKMVDDACMLLADYNGRLAAEIDDRKQLTRMLSDFLRCQKEFLAEKEHKLEEYKRKLARVSQVRKELRTRIQNLPDLSRLPNVTGSHVHLPFAGDIYSDD", "length": 311, "header": "tr|F1NQ92-1|F1NQ92_CHICK Isoform 1 of Regulation of nuclear pre-mRNA domain-containing protein 1A OS=Gallus gallus OX=9031 GN=RPRD1A PE=3 SV=2 CANONICAL=F1NQ92-1" }, "isoforms": [ { "isoform_ac": "A0A8V0XZW8-1", "url": "https://www.uniprot.org/uniprotkb/F1NQ92/entry#A0A8V0XZW8-1", "sequence": { "sequence": "MSAFSEAALERKLSELSNSQQSVQTLSLWLIHHRKHSALIVSVWERELRKAKPNRKLTFLYLANDVIQNSKRKGPEFTKDFAPVIVEAFKHVSSESDESCKKHLGRVLSIWEERSVYENDVLEQLRQALYGDRKVKKRTYEQIKVDENNCSPRSSPTDPPQTMDLIRALQELENAASGDAAVHQRIASLPIEVQDVSLLDRITDKESGEQLSKMVDDACMLLADYNGRLAAEIDDRKQLTRMLSDFLRCQKEFLAEKEHKLEVRIVLF", "length": 268, "header": "tr|A0A8V0XZW8-1|A0A8V0XZW8_CHICK Computationally mapped isoform of Regulation of nuclear pre-mRNA domain-containing protein 1A OS=Gallus gallus OX=9031 GN=RPRD1A PE=3 SV=1 CANONICAL=F1NQ92-1" }, "locus": { "chromosome": "2", "start_pos": 83151237, "end_pos": 83135803, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010020018.1", "url": "https://www.ensembl.org/id/ENSGALT00010020018.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010011566.1", "url": "https://www.ensembl.org/id/ENSGALP00010011566.1" } ] } }, { "isoform_ac": "A0A8V0Y6C6-1", "url": "https://www.uniprot.org/uniprotkb/F1NQ92/entry#A0A8V0Y6C6-1", "sequence": { "sequence": "MEDRSFSSLTNQIKSMHQMCLTLITTVTTKIFPVLIAKPNRKLTFLYLANDVIQNSKRKGPEFTKDFAPVIVEAFKHVSSESDESCKKHLGRVLSIWEERSVYENDVLEQLRQALYGDRKVKKRTYEQIKVDENNCSPRSSPTDPPQTMDLIRALQELENAASGDAAVHQRIASLPIEVQDVSLLDRITDKESGEQLSKMVDDACMLLADYNGRLAAEIDDRKQLTRMLSDFLRCQKEFLAEKEHKLEVRIVLF", "length": 254, "header": "tr|A0A8V0Y6C6-1|A0A8V0Y6C6_CHICK Computationally mapped isoform of Regulation of nuclear pre-mRNA domain containing 1A OS=Gallus gallus OX=9031 GN=RPRD1A PE=3 SV=1 CANONICAL=F1NQ92-1" }, "locus": { "chromosome": "2", "start_pos": 83151237, "end_pos": 83140455, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010020017.1", "url": "https://www.ensembl.org/id/ENSGALT00010020017.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010011565.1", "url": "https://www.ensembl.org/id/ENSGALP00010011565.1" } ] } }, { "isoform_ac": "F1NQ92-1", "url": "https://www.uniprot.org/uniprotkb/F1NQ92/entry#F1NQ92-1", "sequence": { "sequence": "MSAFSEAALERKLSELSNSQQSVQTLSLWLIHHRKHSALIVSVWERELRKAKPNRKLTFLYLANDVIQNSKRKGPEFTKDFAPVIVEAFKHVSSESDESCKKHLGRVLSIWEERSVYENDVLEQLRQALYGDRKVKKRTYEQIKVDENNCSPRSSPTDPPQTMDLIRALQELENAASGDAAVHQRIASLPIEVQDVSLLDRITDKESGEQLSKMVDDACMLLADYNGRLAAEIDDRKQLTRMLSDFLRCQKEFLAEKEHKLEEYKRKLARVSQVRKELRTRIQNLPDLSRLPNVTGSHVHLPFAGDIYSDD", "length": 311, "header": "tr|F1NQ92-1|F1NQ92_CHICK Isoform 1 of Regulation of nuclear pre-mRNA domain-containing protein 1A OS=Gallus gallus OX=9031 GN=RPRD1A PE=3 SV=2 CANONICAL=F1NQ92-1" }, "locus": { "chromosome": "2", "start_pos": 83177838, "end_pos": 83135803, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010020022.1", "url": "https://www.ensembl.org/id/ENSGALT00010020022.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010011570.1", "url": "https://www.ensembl.org/id/ENSGALP00010011570.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-6807505", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6807505", "resource": "Reactome", "description": "RNA polymerase II transcribes snRNA genes" } ], "orthologs": [ { "uniprot_canonical_ac": "D4AAU4-1", "protein_name": "Regulation of nuclear pre-mRNA domain-containing protein 1A", "gene_name": "Rprd1a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLAPPRPAPPPFSTLLLFFPFPLPLPPPGGGSFPRESSARGRARCVTSLPAGRHLARLRPASDSGVVVVRAWGRVGCGGEAATRAATLSSPQLHGVGRRERGFGGMSAFSEAALEKKLSELSNSQQSVQTLSLWLIHHRKHSRPIVTVWERELRKAKPNRKLTFLYLANDVIQNSKRKGPEFTKDFAPVIVEAFKHVSSETDESCKKHLGRVLSIWEERSVYENDVLEQLKHALYGDKKTRKRTYEQIKVDENENCSSLGSPSEPPQTLDLVRALQDLENAASGDAAVHQRIASLPVEVQEVSLLEKITDKESGERLSKMVEDACMLLADYNGRLAAEIDDRKQLTRMLADFLRCQKEALAEKEHKLEEYKRKLARVSLVRKELRARIQSLPDLSRLPNVTGSHMHLPFAGDIYSED", "length": 417 }, "evidence": [ { "id": "F1NQ92", "url": "https://omabrowser.org/oma/group/F1NQ92/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q0P5J9-1", "protein_name": "Regulation of nuclear pre-mRNA domain-containing protein 1A", "gene_name": "RPRD1A", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSAFSEAALEKKLSELSNSQQSVQTLSLWLIHHRKHSRPIVTVWERELRKAKPNRKLTFLYLANDVIQNSKRKGPEFTKDFAPVIVEAFKHVSSETDESCKKHLGRVLSIWEERSVYENDVLEQLKQALYGDKKPRKRTYEQIKVDENENCSSLGSPSEPPQTLDLVRALQDLENAASGDAAVHQRIASLPVEVQEVSLLDKITDKESGERLSKMVEDACMLLADYNGRLAAEIDDRKQLTRMLADFLRCQKEALAEKEHKLEEYKRKLARVSLVRKELRSRIQSLPDLSRLPNVTGSHMHLPFAGDIYSED", "length": 312 }, "evidence": [ { "id": "F1NQ92", "url": "https://omabrowser.org/oma/group/F1NQ92/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q8VDS4-1", "protein_name": "Regulation of nuclear pre-mRNA domain-containing protein 1A", "gene_name": "Rprd1a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAFSEAALEKKLSELSNSQQSVQTLSLWLIHHRKHSRPIVTVWERELRKAKPNRKLTFLYLANDVIQNSKRKGPEFTKDFAPVIVEAFKHVSSETDESCKKHLGRVLSIWEERSVYENDVLEQLKHALYGDKKARKRTYEQIKVDENENCSSLGSPSEPPQTLDLVRALQDLENAASGDAAVHQRIASLPVEVQEVSLLEKITDKESGERLSKMVEDACMLLADYNGRLAAEIDDRKQLTRMLADFLRCQKEALAEKEHKLEEYKRKLARVSLVRKELRARIQSLPDLSRLPNVTGSHMHLPFAGDIYSED", "length": 312 }, "evidence": [ { "id": "F1NQ92", "url": "https://omabrowser.org/oma/group/F1NQ92/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96P16-1", "protein_name": "Regulation of nuclear pre-mRNA domain-containing protein 1A", "gene_name": "RPRD1A", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSAFSEAALEKKLSELSNSQQSVQTLSLWLIHHRKHSRPIVTVWERELRKAKPNRKLTFLYLANDVIQNSKRKGPEFTKDFAPVIVEAFKHVSSETDESCKKHLGRVLSIWEERSVYENDVLEQLKQALYGDKKPRKRTYEQIKVDENENCSSLGSPSEPPQTLDLVRALQDLENAASGDAAVHQRIASLPVEVQEVSLLDKITDKESGERLSKMVEDACMLLADYNGRLAAEIDDRKQLTRMLADFLRCQKEALAEKEHKLEEYKRKLARVSLVRKELRSRIQSLPDLSRLPNVTGSHMHLPFAGDIYSED", "length": 312 }, "evidence": [ { "id": "F1NQ92", "url": "https://omabrowser.org/oma/group/F1NQ92/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "transcription preinitiation complex", "id": "GO:0097550", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097550", "evidence": [ { "database": "UniProtKB", "id": "F1NQ92", "url": "https://www.uniprot.org/uniprotkb/F1NQ92" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "F1NQ92", "url": "https://www.uniprot.org/uniprotkb/F1NQ92" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "F1NQ92", "url": "https://www.uniprot.org/uniprotkb/F1NQ92" } ], "pmid": "" }, { "name": "RNA polymerase II complex binding", "id": "GO:0000993", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000993", "evidence": [ { "database": "UniProtKB", "id": "F1NQ92", "url": "https://www.uniprot.org/uniprotkb/F1NQ92" } ], "pmid": "" }, { "name": "RNA polymerase II C-terminal domain binding", "id": "GO:0099122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099122", "evidence": [ { "database": "UniProtKB", "id": "F1NQ92", "url": "https://www.uniprot.org/uniprotkb/F1NQ92" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "RNA polymerase II promoter clearance", "id": "GO:0001111", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001111", "evidence": [ { "database": "UniProtKB", "id": "F1NQ92", "url": "https://www.uniprot.org/uniprotkb/F1NQ92" } ], "pmid": "" }, { "name": "mRNA 3'-end processing", "id": "GO:0031124", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031124", "evidence": [ { "database": "UniProtKB", "id": "F1NQ92", "url": "https://www.uniprot.org/uniprotkb/F1NQ92" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 149, "end_pos": 151, "annotation": "n_glycosylation_sequon" }, { "start_pos": 293, "end_pos": 295, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1NQ92-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 311, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1NQ92-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1NQ92" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1NQ92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NQ92" }, { "id": "PS51391", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51391" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CID", "eco_id": "ECO_0000259", "start_pos": 1, "end_pos": 133, "start_aa": "Met", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 149, "end_pos": 151 }, { "start_pos": 293, "end_pos": 295 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1NJB8-1", "uniprot_ac": "F1NJB8", "uniprot_id": "F1NJB8_CHICK", "mass": { "chemical_mass": 169389.0, "monoisotopic_mass": 169389.0 }, "refseq": { "ac": "XP_015137683", "name": "PH domain leucine-rich repeat-containing protein phosphatase 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015137683" }, "gene_names": [ { "name": "PHLPP1", "type": "recommended", "evidence": [ { "id": "F1NJB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NJB8" } ] }, { "name": "PHLPP1", "type": "synonym", "evidence": [ { "id": "XP_015137683", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015137683" } ] } ], "protein_names": [ { "name": "protein-serine/threonine phosphatase", "type": "recommended", "evidence": [ { "id": "F1NJB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NJB8/entry#names_and_taxonomy" } ] }, { "name": "3.1.3.16", "type": "synonym", "evidence": [ { "id": "F1NJB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NJB8/entry#names_and_taxonomy" } ] }, { "name": "PH domain leucine-rich repeat-containing protein phosphatase 1", "type": "synonym", "evidence": [ { "id": "XP_015137683", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015137683" } ] }, { "name": "Pleckstrin homology domain-containing family E member 1", "type": "synonym", "evidence": [ { "id": "F1NJB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NJB8/entry#names_and_taxonomy" } ] }, { "name": "Suprachiasmatic nucleus circadian oscillatory protein", "type": "synonym", "evidence": [ { "id": "F1NJB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NJB8/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052533.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015137683", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015137683" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NJB8", "url": "https://www.uniprot.org/uniprotkb/F1NJB8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PHLPP1", "url": "https://www.uniprot.org/uniprotkb/F1NJB8", "locus": { "chromosome": "2", "start_pos": 67716108, "end_pos": 67847758, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010011899", "url": "https://www.ensembl.org/id/ENSGALG00010011899" } ] } } ], "crossref": [ { "id": "ENSGALG00000012888", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000012888", 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"https://www.ebi.ac.uk/interpro/entry/IPR001932", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003591", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003591", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036457", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036457", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050216", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050216", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055071", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055071", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:420904", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420904", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "GHNQICD", "url": "https://omabrowser.org/oma/group/GHNQICD/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y6Y1", "url": "https://www.orthodb.org/?gene=A0A8V0Y6Y1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YBQ8", "url": "https://www.orthodb.org/?gene=A0A8V0YBQ8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YBV9", "url": "https://www.orthodb.org/?gene=A0A8V0YBV9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YD63", "url": "https://www.orthodb.org/?gene=A0A8V0YD63", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YK40", "url": "https://www.orthodb.org/?gene=A0A8V0YK40", "database": "OrthoDB", "categories": [ "Protein 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"https://www.ebi.ac.uk/interpro/entry/pfam/PF23010", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-199418", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-199418", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_015137683", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015137683", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "20629", "url": "https://www.rhea-db.org/rhea/20629", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "47004", "url": "https://www.rhea-db.org/rhea/47004", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0Y6Y1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y6Y1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y6Y1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y6Y1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YBQ8", "url": 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"database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NJB8", "url": "https://www.uniprot.org/uniprotkb/F1NJB8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NJB8-1", "url": "https://www.uniprot.org/uniprotkb/F1NJB8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEPAQQQQQQRAREAAERSPGGKGPATESGAEAAGGPRRRRGAAGGSAPPAALAAPGGAGGGSLLLRRGRLKRNLSAAAAPLGTRSLDRKALLPKPPRQLQPLQPPERDWVRRDLQRGCVHVYERHANRYLRPVLCTLETTAAEVAARLQQPGPRGGGVVRVPGKAGPQPPPPEEGPAAATAEPTAEGERPGSRRGTRGAPPAGGTEEGGSPSPAAPPAELYLAGPPLSCPSLLGELGPAGSDCESFSPSAESVSDRLDPYSSGGGGGSSSSDELEAEPAASDGAEAGAGPGRGRPPPGELSPGAGGGREVPAGPPALFVQLHGETSRRLEGHEKPLQIQNDYLSQLGFRDLWRVQEEGMDAETGCLIRFYAGKPHSIGSSERIQLSGMYNVRKGKIHLPVNRWTRRQAILCGTCLIVSSVKESQTGKMHVLPLIGGKVEEVKKHQHCLAFSSSGPQSQTYYICFDNFTEYLRWLRQASKVASQRISSVDLSCCSLEHLPANLFYSQDLTHLNLKQNFLKLNPSPSASRALSELQRFTKLKSLNLSNNNLGDFPLAVCSIPTLTELNVSCNALRNVPAVVGEMHNLQTFLLDGNFLQSLPDELEHMHQLSYVSLSFNEFTDIPGVLEKLTAMDKLCMSGNCVDTLNLQVLKRMPHIKHVDLRLNSIRRLEADEIDFLHHVTQLDLRDNKLGELDATIFNNVEVLHCERNQLVTLKISGYFLKALYASSNELVHLDVYPVPNYLTYMDISRNHLENLPEWVCDSKKLEVLDVGHNRISELPARLFYNSSLRKLLAGHNLLGRLPDRLERTQVEVLDVQHNQLLELPPNLLLKADSLRFLNASANKLEMLPPATLSEETHSILQELYLTNNNLTDKCVPLLTGHPHLKILHMAYNRLQSFPASKMAKLEELEEIDISGNKLKAIPTTIMNCRRMHTVIAHSNCIEVFPEVMQLSEIKCVDLSCNELSEITLPENLPPKLQELDLTGNPRLALDHKTLELLNNIRCFKIDQPSAGDASGAPAVWSHGYTEASGVKNKLCVAALSANNFCDNREALYGVFDGDRNVEVPYLLQCTMSDILAEELQKTKNEEEYMINTFIVMQRKLGTAGQKLGGSAVLCHIKHDPMDPGGCFTLTSANVGKCQTVLCRNGKPLPLSRCYVMSCEEELKRIKQHKAIITEDGKVNGVTDSTRILGYTFLHPSVVPRPHVQSITLTPQDEFFILGSKGLWDSLSMDEAVEAVRNVPDALAAAKKLCTLAQSYGCNDSISAVVVQLNVTEDSFCCCELNGVPPPSPGIFPQSVNVVIKDRPADALGMPSSSSGMASEISSEISTSEMSSEVGSTASDEPPQVAMNESSPAYPGEQRCMLHPVCLSNSFQRQLSSATFSSAFSDNGLDSDDEEPIEGVFTNGSRVEVEVDIHCSRAKEKQLLQVPVEASDEGIVISANEDEPGLPKKAEYSATGTIGRRRGNGSVAPQERSHNLIEVATDAPLRKTGGYFAAPAQPDPDDQFIIPPELEEEVKEIMKQHQEQQQQQQQQQQQQQRQYQMDHLADYYDTPL", "length": 1552, "header": "tr|F1NJB8-1|F1NJB8_CHICK Isoform 1 of protein-serine/threonine phosphatase OS=Gallus gallus OX=9031 GN=PHLPP1 PE=4 SV=3 CANONICAL=F1NJB8-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Y6Y1-1", "url": "https://www.uniprot.org/uniprotkb/F1NJB8/entry#A0A8V0Y6Y1-1", "sequence": { "sequence": "MEPAQQQQQQRAREAAERSPGGKGPATESGAEAAGGPRRRRGAAGGSAPPAALAAPGGAGGGSLLLRRGRLKRNLSAAAAPLGTRSLDRKALLPKPPRQLQPLQPPERDWVRRDLQRGCVHVYERHANRYLRPVLCTLETTAAEVAARLQQPGPRGGGVVRVPGKGPAAATAEPTAEGERPGSRRGTRGAPPAGGTEEGGSPSPAAPPAELYLAGPPLSCPSLLGELGPAGSDCESFSPSAESVSDRLDPYSSGGGGGSSSSDELEAGAGPGRGRPPPGELSPGAGGGREVPAGPPALFVQLHGETSRRLEGHEKPLQIQNDYLSQLGFRDLWRVQEEGMDAETGCLIRFYAGKPHSIGSSERIQLSGMYNVRKGKIHLPVNRWTRRQAILCGTCLIVSSVKESQTGKMHVLPLIGGKVEEVKKHQHCLAFSSSGPQSQTYYICFDNFTEYLRWLRQASKVASQRISSVDLSCCSLEHLPANLFYSQDLTHLNLKQNFLKLNPSPSASRALSELQRFTKLKSLNLSNNNLGDFPLAVCSIPTLTELNVSCNALRNVPAVVGEMHNLQTFLLDGNFLQSLPDELEHMHQLSYVSLSFNEFTDIPGVLEKLTAMDKLCMSGNCVDTLNLQVLKRMPHIKHVDLRLNSIRRLEADEIDFLHHVTQLDLRDNKLGELDATIFNNVEVLHCERNQLVTLKISGYFLKALYASSNELVHLDVYPVPNYLTYMDISRNHLENLPEWVCDSKKLEVLDVGHNRISELPARLFYNSSLRKLLAGHNLLGRLPDRLERTQVEVLDVQHNQLLELPPNLLLKADSLRFLNASANKLEMLPPATLSEETHSILQELYLTNNNLTDKCVPLLTGHPHLKILHMAYNRLQSFPASKMAKLEELEEIDISGNKLKAIPTTIMNCRRMHTVIAHSNCIEVFPEVMQLSEIKCVDLSCNELSEITLPENLPPKLQELDLTGNPRLALDHKTLELLNNIRCFKIDQPSAGDASGAPAVWSHGYTEASGVKNKLCVAALSANNFCDNREALYGVFDGDRNVEVPYLLQCTMSDILAEELQKTKNEEEYMINTFIVMQRKLGTAGQKLGGSAVLCHIKHDPMDPGGCFTLTSANVGKCQTVLCRNGKPLPLSRCYVMSCEEELKRIKQHKAIITEDGKVNGVTDSTRILGYTFLHPSVVPRPHVQSITLTPQDEFFILGSKGLWDSLSMDEAVEAVRNVPDALAAAKKLCTLAQSYGCNDSISAVVVQLNVTEDSFCCCELNGVPPPSPGIFPQSVNVVIKDRPADALGMPSSSSGMASEISSEISTSEMSSEVGSTASDEPPQVAMNESSPAYPGEQRCMLHPVCLSNSFQRQLSSATFSSAFSDNGLDSDDEEPIEGVFTNGSRVEVEVDIHCSRAKEKQLLQVPVEASDEGIVISANEDEPGLPKKAEYSATGTIGRRRGNGSVAPQERSHNLIEVATDAPLRKTGGYFAAPAQPDPDDQFIIPPELEEEVKEIMKQHQEQQQQQQQQQQQQQRQYQMDHLADYYDTPL", "length": 1532, "header": "tr|A0A8V0Y6Y1-1|A0A8V0Y6Y1_CHICK Computationally mapped isoform of protein-serine/threonine phosphatase OS=Gallus gallus OX=9031 GN=PHLPP1 PE=4 SV=1 CANONICAL=F1NJB8-1" }, "locus": { "chromosome": "2", "start_pos": 67847034, "end_pos": 67717029, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028595.1", "url": "https://www.ensembl.org/id/ENSGALT00010028595.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016423.1", "url": "https://www.ensembl.org/id/ENSGALP00010016423.1" } ] } }, { "isoform_ac": "A0A8V0YBQ8-1", "url": "https://www.uniprot.org/uniprotkb/F1NJB8/entry#A0A8V0YBQ8-1", "sequence": { "sequence": "MEPAQQQQQQRAREAAERSPGGKGPATESGAEAAGGPRRRRGAAGGSAPPAALAAPGGAGGGSLLLRRGRLKRNLSAAAAPLGTRSLDRKALLPKPPRQLQPLQPPERDWVRRDLQRGCVHVYERHANRYLRPVLCTLETTAAEVPAGPPALFVQLHGETSRRLEGHEKPLQIQNDYLSQLGFRDLWRVQEEGMDAETGCLIRFYAGKPHSIGSSERIQLSGMYNVRKGKIHLPVNRWTRRQAILCGTCLIVSSVKESQTGKMHVLPLIGGKVEEVKKHQHCLAFSSSGPQSQTYYICFDNFTEYLRWLRQASKVASQRISSVDLSCCSLEHLPANLFYSQDLTHLNLKQNFLKLNPSPSASRLKSLNLSNNNLGDFPLAVCSIPTLTELNVSCNALRNVPAVVGEMHNLQTFLLDGNFLQSLPDELEHMHQLSYVSLSFNEFTDIPGVLEKLTAMDKLCMSGNCVDTLNLQVLKRMPHIKHVDLRRLEADEIDFLHHVTQLDLRDNKLGELDATIFNNVEVLHCERNQLVTLKISGYFLKALYASSNELVHLDVYPVPNYLTYMDISRNHLENLPEWVCDSKKLEVLDVGHNRISELPARLFYNSSLRKLLAGHNLLGRLPDRLERTQVEVLDVQHNQLLELPPNLLLKADSLRFLNASANKLEMLPPATLSEETHSILQELYLTNNNLTDKCVPLLTGHPHLKILHMAYNRLQSFPASKMAKLEELEEIDISGNKLKAIPTTIMNCRRMHTVIAHSNCIEVFPEVMQLSEIKCVDLSCNELSEITLPENLPPKLQELDLTGNPRLALDHKTLELGNGKTLLSQVPLPCRISALNGCWISNLVVLLLCFTRLCVAALSANNFCDNREALYGVFDGDRNVEVPYLLQCTMSDILAEELQKTKNEEEYMINTFIVMQRKLGTAGQKLGGSAVLCHIKHDPMDPGGCFTLTSANVGKCQTVLCRNGKPLPLSRCYVMSCEEELKRIKQHKAIITEDGKVNGVTDSTRILGYTFLHPSVVPRPHVQSITLTPQDEFFILGSKGLWDSLSMDEAVEAVRNVPDALAAAKKLCTLAQSYGCNDSISAVVVQLNVTEDSFCCCELNGVPPPSPGIFPQSVNVVIKDRPADALGMPSSSSGMASEISSEISTSEMSSEVGSTASDEPPQVAMNESSPAYPGEQRCMLHPVCLSNSFQRQLSSATFSSAFSDNGLDSDDEEPIEGVFTNGSRVEVEVDIHCSRAKEKQLLQVPVEASDEGIVISANEDEPGLPKKAEYSATGTIGRRRGNGSVAPQERSHNLIEVATDAPLRKTGGYFAAPAQPDPDDQFIIPPELEEEVKEIMKQHQEQQQQQQHRGFPSTFPLYTSFSLSCHYR", "length": 1368, "header": "tr|A0A8V0YBQ8-1|A0A8V0YBQ8_CHICK Computationally mapped isoform of protein-serine/threonine phosphatase OS=Gallus gallus OX=9031 GN=PHLPP1 PE=4 SV=1 CANONICAL=F1NJB8-1" }, "locus": { "chromosome": "2", "start_pos": 67847034, "end_pos": 67716895, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028545.1", "url": "https://www.ensembl.org/id/ENSGALT00010028545.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016386.1", "url": "https://www.ensembl.org/id/ENSGALP00010016386.1" } ] } }, { "isoform_ac": "A0A8V0YBV9-1", "url": "https://www.uniprot.org/uniprotkb/F1NJB8/entry#A0A8V0YBV9-1", "sequence": { "sequence": "TKQPHRCVYTPLTPPAPRHVPPHPLGPAGSDCESFSPSAESVSDRLDPYSSGGGGGSSSSDELEAEPAASDGAEAGAGPGRGRPPPGELSPGAGGGREVPAGPPALFVQLHGETSRRLEGHEKPLQIQNDYLSQLGFRDLWRVQEEGMDAETGCLIRFYAGKPHSIGSSERIQLSGMYNVRKGKIHLPVNRWTRRQAILCGTCLIVSSVKESQTGKMHVLPLIGGKVEEVKKHQHCLAFSSSGPQSQTYYICFDNFTEYLRWLRQASKVASQRISSVDLSCCSLEHLPANLFYSQDLTHLNLKQNFLKLNPTSGLSTLFLFTKLKSLNLSNNNLGDFPLAVCSIPTLTELNVSCNALRNVPAVVGEMHNLQTFLLDGNFLQSLPDELEHMHQLSYVSLSFNEFTDIPGVLEKLTAMDKLCMSGNCVDTLNLQVLKRMPHIKHVDLRRLEADEIDFLHHVTQLDLRDNKLGELDATIFNNVEVLHCERNQLVTLKISGYFLKALYASSNELVHLDVYPVPNYLTYMDISRNHLENLPEWVCDSKKLEVLDVGHNRISELPARLFYNSSLRKLLAGHNLLGRLPDRLERTQVEVLDVQHNQLLELPPNLLLKADSLRFLNASANKLEMLPPATLSEETHSILQELYLTNNNLTDKCVPLLTGHPHLKILHMAYNRLQSFPASKMAKLEELEEIDISGNKLKAIPTTIMNCRRMHTVIAHSNCIEVFPEVMQLSEIKCVDLSCNELSEITLPENLPPKLQELDLTGNPRLALDHKTLELLNVTDTFSLRKLCVAALSANNFCDNREALYGVFDGDRNVEVPYLLQCTMSDILAEELQKTKNEEEYMINTFIVMQRKLGTAGQKLGGSAVLCHIKHDPMDPGGCFTLTSANVGKCQTVLCRNGKPLPLSRCYVMSCEEELKRIKQHKAIITEDGKVNGVTDSTRILGYTFLHPSVVPRPHVQSITLTPQDEFFILGSKGLWDSLSMDEAVEAVRNVPDALAAAKKLCTLAQSYGCNDSISAVVVQLNVTEDSFCCCELNGVPPPSPGIFPQSVNVVIKDRPADALGMPSSSSGMASEISSEISTSEMSSEVGSTASDEPPQVAMNESSPAYPGEQRCMLHPVCLSNSFQRQLSSATFSSAFSDNGLDSDDEEPIEGVFTNGSRVEVEVDIHCSRAKEKQLLQVPVEASDEGIVISANEDEPGLPKKAEYSATGTIGRRRGNGSVAPQERSHNLIEVATDAPLRKTGGYFAAPAQPDPDDQFIIPPELEEEVKEIMKQHQEQQQQQQQQQQQQQRQYQMDHLADYYDTPL", "length": 1305, "header": "tr|A0A8V0YBV9-1|A0A8V0YBV9_CHICK Computationally mapped isoform of protein-serine/threonine phosphatase OS=Gallus gallus OX=9031 GN=PHLPP1 PE=4 SV=1 CANONICAL=F1NJB8-1" }, "locus": { "chromosome": "2", "start_pos": 67847758, "end_pos": 67717029, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028621.1", "url": "https://www.ensembl.org/id/ENSGALT00010028621.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016442.1", "url": "https://www.ensembl.org/id/ENSGALP00010016442.1" } ] } }, { "isoform_ac": "A0A8V0YD63-1", "url": "https://www.uniprot.org/uniprotkb/F1NJB8/entry#A0A8V0YD63-1", "sequence": { "sequence": "MGEAPPRRAAVSSRRATSPERRGRLIFMRRGRARRRARWLAESVSDRLDPYSSGGGGGSSSSDELEAEPAASDGAEAGAGPGRGRPPPGELSPGAGGGREVPAGPPALFVQLHGETSRRLEGHEKPLQIQNDYLSQLGFRDLWRVQEEGMDAETGCLIRFYAGKPHSIGSSERIQLSGMYNVRKGKIHLPVNRWTRRQAILCGTCLIVSSVKESQTGKMHVLPLIGGKVEEVKKHQHCLAFSSSGPQSQTYYICFDNFTEYLRWLRQASKVASQRISSVDLSCCSLEHLPANLFYSQDLTHLNLKQNFLKLNPTSGLSTLFLFTKLKSLNLSNNNLGDFPLAVCSIPTLTELNVSCNALRNVPAVVGEMHNLQTFLLDGNFLQSLPDELEHMHQLSYVSLSFNEFTDIPGVLEKLTAMDKLCMSGNCVDTLNLQVLKRMPHIKHVDLRRLEADEIDFLHHVTQLDLRDNKLGELDATIFNNVEVLHCERNQLVTLKISGYFLKALYASSNELVHLDVYPVPNYLTYMDISRNHLENLPEWVCDSKKLEVLDVGHNRISELPARLFYNSSLRKLLAGHNLLGRLPDRLERTQVEVLDVQHNQLLELPPNLLLKADSLRFLNASANKLEMLPPATLSEETHSILQELYLTNNNLTDKCVPLLTGHPHLKILHMAYNRLQSFPASKMAKLEELEEIDISGNKLKAIPTTIMNCRRMHTVIAHSNCIEVFPEVMQLSEIKCVDLSCNELSEITLPENLPPKLQELDLTGNPRLALDHKTLELLNVTDTFSLRKLCVAALSANNFCDNREALYGVFDGDRNVEVPYLLQCTMSDILAEELQKTKNEEEYMINTFIVMQRKLGTAGQKLGGSAVLCHIKHDPMDPGGCFTLTSANVGKCQTVLCRNGKPLPLSRCYVMSCEEELKRIKQHKAIITEDGKVNGVTDSTRILGYTFLHPSVVPRPHVQSITLTPQDEFFILGSKGLWDSLSMDEAVEAVRNVPDALAAAKKLCTLAQSYGCNDSISAVVVQLNVTEDSFCCCELNGVPPPSPGIFPQSVNVVIKDRPADALGMPSSSSGMASEISSEISTSEMSSEVGSTASDEPPQVAMNESSPAYPGEQRCMLHPVCLSNSFQRQLSSATFSSAFSDNGLDSDDEEPIEGVFTNGSRVEVEVDIHCSRAKEKQLLQVPVEASDEGIVISANEDEPGLPKKAEYSATGTIGRRRGNGSVAPQERSHNLIEVATDAPLRKTGGYFAAPAQPDPDDQFIIPPELEEEVKEIMKQHQEQQQQQQQQQQQQQRQYQMDHLADYYDTPL", "length": 1307, "header": "tr|A0A8V0YD63-1|A0A8V0YD63_CHICK Computationally mapped isoform of protein-serine/threonine phosphatase OS=Gallus gallus OX=9031 GN=PHLPP1 PE=4 SV=1 CANONICAL=F1NJB8-1" }, "locus": { "chromosome": "2", "start_pos": 67847355, "end_pos": 67717029, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028614.1", "url": "https://www.ensembl.org/id/ENSGALT00010028614.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016435.1", "url": "https://www.ensembl.org/id/ENSGALP00010016435.1" } ] } }, { "isoform_ac": "A0A8V0YK40-1", "url": "https://www.uniprot.org/uniprotkb/F1NJB8/entry#A0A8V0YK40-1", "sequence": { "sequence": "MEPAQQQQQQRAREAAERSPGGKGPATESGAEAAGGPRRRRGAAGGSAPPAALAAPGGAGGGSLLLRRGRLKRNLSAAAAPLGTRSLDRKALLPKPPRQLQPLQPPERDWVRRDLQRGCVHVYERHANRYLRPVLCTLETTAAEVAARLQQPGPRGGGVVRVPGKAGPQPPPPEEGPAAATAEPTAEGERPGSRRGTRGAPPAGGTEEGGSPSPAAPPAELYLAGPPLSCPSLLGELGPAGSDCESFSPSAESVSDRLDPYSSGGGGGSSSSDELEAEPAASDGAEAGAGPGRGRPPPGELSPGAGGGREVPAGPPALFVQLHGETSRRLEGHEKPLQIQNDYLSQLGFRDLWRVQEEGMDAETGCLIRFYAGKPHSIGSSERIQLSGMYNVRKGKIHLPVNRWTRRQAILCGTCLIVSSVKESQTGKMHVLPLIGGKVEEVKKHQHCLAFSSSGPQSQTYYICFDNFTEYLRWLRQASKVASQRISSVDLSCCSLEHLPANLFYSQDLTHLNLKQNFLKLNPTSGLSTLFLFTKLKSLNLSNNNLGDFPLAVCSIPTLTELNVSCNALRNVPAVVGEMHNLQTFLLDGNFLQSLPDELEHMHQLSYVSLSFNEFTDIPGVLEKLTAMDKLCMSGNCVDTLNLQVLKRMPHIKHVDLRRLEADEIDFLHHVTQLDLRDNKLGELDATIFNNVEVLHCERNQLVTLKISGYFLKALYASSNELVHLDVYPVPNYLTYMDISRNHLENLPEWVCDSKKLEVLDVGHNRISELPARLFYNSSLRKLLAGHNLLGRLPDRLERTQVEVLDVQHNQLLELPPNLLLKADSLRFLNASANKLEMLPPATLSEETHSILQELYLTNNNLTDKCVPLLTGHPHLKILHMAYNRLQSFPASKMAKLEELEEIDISGNKLKAIPTTIMNCRRMHTVIAHSNCIEVFPEVMQLSEIKCVDLSCNELSEITLPENLPPKLQELDLTGNPRLALDHKTLELLNVTDTFSLRKLCVAALSANNFCDNREALYGVFDGDRNVEVPYLLQCTMSDILAEELQKTKNEEEYMINTFIVMQRKLGTAGQKLGGSAVLCHIKHDPMDPGGCFTLTSANVGKCQTVLCRNGKPLPLSRCYVMSCEEELKRIKQHKAIITEDGKVNGVTDSTRILGYTFLHPSVVPRPHVQSITLTPQDEFFILGSKGLWDSLSMDEAVEAVRNVPDALAAAKKLCTLAQSYGCNDSISAVVVQLNVTEDSFCCCELNGVPPPSPGIFPQSVNVVIKDRPADALGMPSSSSGMASEISSEISTSEMSSEVGSTASDEPPQVAMNESSPAYPGEQRCMLHPVCLSNSFQRQLSSATFSSAFSDNGLDSDDEEPIEGVFTNGSRVEVEVDIHCSRAKEKQLLQVPVEASDEGIVISANEDEPGLPKKAEYSATGTIGRRRGNGSVAPQERSHNLIEVATDAPLRKTGGYFAAPAQPDPDDQFIIPPELEEEVKEIMKQHQEQQQQQQQQQQQQQRQYQMDHLADYYDTPL", "length": 1517, "header": "tr|A0A8V0YK40-1|A0A8V0YK40_CHICK Computationally mapped isoform of protein-serine/threonine phosphatase OS=Gallus gallus OX=9031 GN=PHLPP1 PE=4 SV=1 CANONICAL=F1NJB8-1" }, "locus": { "chromosome": "2", "start_pos": 67847034, "end_pos": 67717029, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028605.1", "url": "https://www.ensembl.org/id/ENSGALT00010028605.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016429.1", "url": "https://www.ensembl.org/id/ENSGALP00010016429.1" } ] } }, { "isoform_ac": "F1NJB8-1", "url": "https://www.uniprot.org/uniprotkb/F1NJB8/entry#F1NJB8-1", "sequence": { "sequence": "MEPAQQQQQQRAREAAERSPGGKGPATESGAEAAGGPRRRRGAAGGSAPPAALAAPGGAGGGSLLLRRGRLKRNLSAAAAPLGTRSLDRKALLPKPPRQLQPLQPPERDWVRRDLQRGCVHVYERHANRYLRPVLCTLETTAAEVAARLQQPGPRGGGVVRVPGKAGPQPPPPEEGPAAATAEPTAEGERPGSRRGTRGAPPAGGTEEGGSPSPAAPPAELYLAGPPLSCPSLLGELGPAGSDCESFSPSAESVSDRLDPYSSGGGGGSSSSDELEAEPAASDGAEAGAGPGRGRPPPGELSPGAGGGREVPAGPPALFVQLHGETSRRLEGHEKPLQIQNDYLSQLGFRDLWRVQEEGMDAETGCLIRFYAGKPHSIGSSERIQLSGMYNVRKGKIHLPVNRWTRRQAILCGTCLIVSSVKESQTGKMHVLPLIGGKVEEVKKHQHCLAFSSSGPQSQTYYICFDNFTEYLRWLRQASKVASQRISSVDLSCCSLEHLPANLFYSQDLTHLNLKQNFLKLNPSPSASRALSELQRFTKLKSLNLSNNNLGDFPLAVCSIPTLTELNVSCNALRNVPAVVGEMHNLQTFLLDGNFLQSLPDELEHMHQLSYVSLSFNEFTDIPGVLEKLTAMDKLCMSGNCVDTLNLQVLKRMPHIKHVDLRLNSIRRLEADEIDFLHHVTQLDLRDNKLGELDATIFNNVEVLHCERNQLVTLKISGYFLKALYASSNELVHLDVYPVPNYLTYMDISRNHLENLPEWVCDSKKLEVLDVGHNRISELPARLFYNSSLRKLLAGHNLLGRLPDRLERTQVEVLDVQHNQLLELPPNLLLKADSLRFLNASANKLEMLPPATLSEETHSILQELYLTNNNLTDKCVPLLTGHPHLKILHMAYNRLQSFPASKMAKLEELEEIDISGNKLKAIPTTIMNCRRMHTVIAHSNCIEVFPEVMQLSEIKCVDLSCNELSEITLPENLPPKLQELDLTGNPRLALDHKTLELLNNIRCFKIDQPSAGDASGAPAVWSHGYTEASGVKNKLCVAALSANNFCDNREALYGVFDGDRNVEVPYLLQCTMSDILAEELQKTKNEEEYMINTFIVMQRKLGTAGQKLGGSAVLCHIKHDPMDPGGCFTLTSANVGKCQTVLCRNGKPLPLSRCYVMSCEEELKRIKQHKAIITEDGKVNGVTDSTRILGYTFLHPSVVPRPHVQSITLTPQDEFFILGSKGLWDSLSMDEAVEAVRNVPDALAAAKKLCTLAQSYGCNDSISAVVVQLNVTEDSFCCCELNGVPPPSPGIFPQSVNVVIKDRPADALGMPSSSSGMASEISSEISTSEMSSEVGSTASDEPPQVAMNESSPAYPGEQRCMLHPVCLSNSFQRQLSSATFSSAFSDNGLDSDDEEPIEGVFTNGSRVEVEVDIHCSRAKEKQLLQVPVEASDEGIVISANEDEPGLPKKAEYSATGTIGRRRGNGSVAPQERSHNLIEVATDAPLRKTGGYFAAPAQPDPDDQFIIPPELEEEVKEIMKQHQEQQQQQQQQQQQQQRQYQMDHLADYYDTPL", "length": 1552, "header": "tr|F1NJB8-1|F1NJB8_CHICK Isoform 1 of protein-serine/threonine phosphatase OS=Gallus gallus OX=9031 GN=PHLPP1 PE=4 SV=3 CANONICAL=F1NJB8-1" }, "locus": { "chromosome": "2", "start_pos": 67847034, "end_pos": 67717029, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028588.1", "url": "https://www.ensembl.org/id/ENSGALT00010028588.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016418.1", "url": "https://www.ensembl.org/id/ENSGALP00010016418.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "gga:420904", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420904", "resource": "KEGG Pathway" }, { "id": "R-GGA-199418", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-199418", "resource": "Reactome", "description": "Negative regulation of the PI3K/AKT network" } ], "orthologs": [ { "uniprot_canonical_ac": "O60346-1", "protein_name": "PH domain leucine-rich repeat-containing protein phosphatase 1", "gene_name": "PHLPP1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEPAAAATVQRLPELGREDRASAPAAAAAAAAAAAAAAAALAAAAGGGRSPEPALTPAAPSGGNGSGSGAREEAPGEAPPGPLPGRAGGAGRRRRRGAPQPIAGGAAPVPGAGGGANSLLLRRGRLKRNLSAAAAAASSSSSSSAAAASHSPGAAGLPASCSASASLCTRSLDRKTLLLKHRQTLQLQPSDRDWVRHQLQRGCVHVFDRHMASTYLRPVLCTLDTTAGEVAARLLQLGHKGGGVVKVLGQGPGAAAAREPAEPPPEAGPRLAPPEPRDSEVPPARSAPGAFGGPPRAPPADLPLPVGGPGGWSRRASPAPSDSSPGEPFVGGPVSSPRAPRPVVSDTESFSLSPSAESVSDRLDPYSSGGGSSSSSEELEADAASAPTGVPGQPRRPGHPAQPLPLPQTASSPQPQQKAPRAIDSPGGAVREGSCEEKAAAAVAPGGLQSTPGRSGVTAEKAPPPPPPPTLYVQLHGETTRRLEAEEKPLQIQNDYLFQLGFGELWRVQEEGMDSEIGCLIRFYAGKPHSTGSSERIQLSGMYNVRKGKMQLPVNRWTRRQVILCGTCLIVSSVKDSLTGKMHVLPLIGGKVEEVKKHQHCLAFSSSGPQSQTYYICFDTFTEYLRWLRQVSKVASQRISSVDLSCCSLEHLPANLFYSQDLTHLNLKQNFLRQNPSLPAARGLNELQRFTKLKSLNLSNNHLGDFPLAVCSIPTLAELNVSCNALRSVPAAVGVMHNLQTFLLDGNFLQSLPAELENMKQLSYLGLSFNEFTDIPEVLEKLTAVDKLCMSGNCVETLRLQALRKMPHIKHVDLRLNVIRKLIADEVDFLQHVTQLDLRDNKLGDLDAMIFNNIEVLHCERNQLVTLDICGYFLKALYASSNELVQLDVYPVPNYLSYMDVSRNRLENVPEWVCESRKLEVLDIGHNQICELPARLFCNSSLRKLLAGHNQLARLPERLERTSVEVLDVQHNQLLELPPNLLMKADSLRFLNASANKLESLPPATLSEETNSILQELYLTNNSLTDKCVPLLTGHPHLKILHMAYNRLQSFPASKMAKLEELEEIDLSGNKLKAIPTTIMNCRRMHTVIAHSNCIEVFPEVMQLPEIKCVDLSCNELSEVTLPENLPPKLQELDLTGNPRLVLDHKTLELLNNIRCFKIDQPSTGDASGAPAVWSHGYTEASGVKNKLCVAALSVNNFCDNREALYGVFDGDRNVEVPYLLQCTMSDILAEELQKTKNEEEYMVNTFIVMQRKLGTAGQKLGGAAVLCHIKHDPVDPGGSFTLTSANVGKCQTVLCRNGKPLPLSRSYIMSCEEELKRIKQHKAIITEDGKVNGVTESTRILGYTFLHPSVVPRPHVQSVLLTPQDEFFILGSKGLWDSLSVEEAVEAVRNVPDALAAAKKLCTLAQSYGCHDSISAVVVQLSVTEDSFCCCELSAGGAVPPPSPGIFPPSVNMVIKDRPSDGLGVPSSSSGMASEISSELSTSEMSSEVGSTASDEPPPGALSENSPAYPSEQRCMLHPICLSNSFQRQLSSATFSSAFSDNGLDSDDEEPIEGVFTNGSRVEVEVDIHCSRAKEKEKQQHLLQVPAEASDEGIVISANEDEPGLPRKADFSAVGTIGRRRANGSVAPQERSHNVIEVATDAPLRKPGGYFAAPAQPDPDDQFIIPPELEEEVKEIMKHHQEQQQQQQPPPPPQLQPQLPRHYQLDQLPDYYDTPL", "length": 1717 }, "evidence": [ { "id": "F1NJB8", "url": "https://omabrowser.org/oma/group/F1NJB8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8CHE4-1", "protein_name": "PH domain leucine-rich repeat-containing protein phosphatase 1", "gene_name": "Phlpp1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEPAAAAPAQRLADPTGEDQALAAAAAEGGRCPDPALSAAAPSGGNGGAAREEAPCEAPPGPLPGRAGGTGRRRRRGAPQPAAGGAAPVPAAGGGANSLLLKRGRLKRNLSAAAAASSSSSPSSASSAAGGLPASCSASASLCTRSLDRKTLLLKHRQLLQLQPSDRDWVRHQLQRGCVHVFDRHMASSYLRPVLCTLDTTAAEVAARLLQLGHKGGGVVKVLGYGPPPAAAPAASDQTLDGEHGRDVEPPPSSGTVGAVRGPARAPPADLPLPGGAWTRCAPRISPAPSDSSPGELFAGGPGSPPRAPRPASDTESFSLSPSAESVSDRLDPYSSGGGGSSSSSEELEADPAMPHRPGRPAQPRPPSPKTSALLQPKAPTGVDSTGVIAGEGPGDDKAMAAAAPDVPLSTSGRIRETVQKTSPPSLYVQLHGETTRRLEADEKPLQIQNDYLFQLGFGELWRVQEEGMDSEIGCLIRFYAGKPHSTGSSERIQLSGMYNVRKGKMQLPVNRWTRRQVILCGTCLIVSSVKDSVSGKMHVLPLIGGKVEEVKKHQHCLAFSSSGPQSQTYYICFDTFTEYLRWLRQVSKVASQRISSVDLSCCSLEHLPANLFYSQDLTHLNLKQNFLRQTPTLPAARGLGELQRFTKLKSLNLSNNHLGAFPSAVCSIPTLAELNVSCNALREVPAAVGDMQNLQTFLLDGNFLQSLPAELESMHQLSYLGLSFNEFTDIPEVLEKLTAVDKLCMAGNCVETLRLQALRRMPHIKHVDLRLNILRKLMADEVDFVQHVTQLDLRDNKLGDLDAMIFNNIEVLHCERNQLVTLNVCGYFLKALYASSNELAQLDVYPVPNYLSYMDVSRNCLESVPEWVCESRKLEVLDIGHNQICELPARLFCNSSLRKLLAGHNRLARLPERLERTSVEVLDVQHNQITELPPNLLMKADSLRFLNASANKLETLPPATLSEETSSILQELYLTNNCLTDKCVPLLTGHPRLKILHMAYNRLQSFPASKMAKLEELEEIDISGNKLKAIPTTIMNCRRMHTVIAHSNCIEVFPEVMQLPEVKCVDLSCNELSEITLPENLPPKLQELDLTGNPRLALDHKSLELLNNIRCFKIDQPSAGDASGAPAVWSHGYTEASGVKNKLCVAALSVNNFRDNREALYGVFDGDRNVEVPYLLQCTMSDILAEELQKTKNEEEYMVNTFIVMQRKLGTAGQKLGGAAVLCHIKPDPVDLGGSFTLTSANVGKCQTVLCRNGKPLSLSRSYIMSCEEERKRIKQHKAIITEDGKVNGVTESTRILGYTFLHPSVVPRPHVQSVLLTPQDEFFILGSKGLWDSLSIDEAVEAVRNVPDALAAAKKLCTLAQSYGCHDSISAVVVQLSVTEDSFCCCELSAGGSMPPPSPGIFPPSVNMVIKDRPSDGLGVPSSSSGMASEISSELSTSEMSSEVGSTASDEPPSGVLNESSPAYPNEQRCMLHPVCLSNSFQRQLSSATFSSAFSDNGLDSDDEEPIEGVFSNGSRVEVEVDIHCSRAKEKERQQHLLQVPAEASDEGIVISANEDESGLSKKADFSAVGTIGRRRANGSVAPQERSHNVIEVAADAPLRKPGGYFAAPAQPDPDDQFIIPPELEEEVKEIMKHHQEQQQQQQQQQLPPPPQPPQPQPQPQPQPQPQPQRHFQMDHLPDCYDTPL", "length": 1687 }, "evidence": [ { "id": "F1NJB8", "url": "https://omabrowser.org/oma/group/F1NJB8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9WTR8-1", "protein_name": "PH domain leucine-rich repeat protein phosphatase 1", "gene_name": "Phlpp1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEPAAAAPAQRLADPTGEDRAPAAAAAAEGGRSPDSVLSAAAPSGGNGGAAREEAPCEAPPGPLPGRAGGTGRRRRRGVPQPAAGGAAPVTAAGGGANSLLLRRGRLKRNLSAAASSSSSPSSASSAAGGLPASCSASASLCTRSLDRKTLLQKHRQLLQLQPSDRDWVRHQLQRGCVHVFDRHMASSYLRPVLCTLDTTAAEVAARLLQLGHKGGGVVKVLGHGPPPAAAPAASDQTPATELGRDVEPPPSSSTVGAVRGPARAPPADLPLPGGAWTRCAPRVNPAPSDSSPGELFAGGPCSPSRAPRPASDTESFSLSPSAESVSDRLDPYSSGGGSSSSSEELEADPATVLTGPSGPPHHPVRSSQPRPPSPKTSALLQPKAPTGVDGTGLVVGEGPGDDKAVAAAAPGVPLWTPGRIRETVQKTSSPPSLYVQLHGETTRRLEADEKPLQIQNDYLFQLGFGELWRVQEEGMDSEIGCLIRFYAGKPHSTGSSERIQLSGMYNVRKGKMQLPVNRWTRRQVILCGTCLIVSSVKDSSSGKMHVLPLIGGKVEEVKKHQHCLAFSSSGPQSQTYYICFDTFTEYLRWLRQVSKVASQRISSVDLSCCSLEHLPANLFYSQDLTHLNLKQNFLRQNPSLPAARGLGELQRFTKLKSLNLSNNHLGAFPSAVCSIPTLAELNVSCNALQEVPAAVGAMQNLQTFLLDGNFLQSLPAELENMHQLSYLGLSFNEFTDIPEVLEKLTAVDKLCMAGNCMETLRLQALRRMPHIKHVDLRLNILRKLITDEVDFLQHVTQLDLRDNKLGDLDAMIFNNIEVLHCERNQLVTLNICGYFLKALYASSNELVQLDVYPVPNYLSYMDVSRNCLESVPEWVCESRKLEVLDIGHNQICELPARLFCNSSLRKLLAGHNRLARLPERLERTSVEVLDVQHNQIIELPPNLLMKADSLRFLNASANKLETLPPATLSEETSSILQELYLTNNSLTDKCVPLLTGHPRLKILHMAYNRLQSFPASKMAKLEELEEIDISGNKLKAIPTTIMNCRRMHTVIAHSNCIEVFPEVMQLPEVKCVDLSCNELSEITLPENLPPKLQELDLTGNPRLALDHKSLELLNNIRCFKIDQPSAGDASGAPAVWSHGYTEASGVKNKLCVAALSVNNFRDNREALYGVFDGDRNVEVPYLLQCTMSDILAEELQKTKNEEEYMVNTFIVMQRKLGTAGQKLGGAAVLCHIRHDPVDLGGSFTLTSANVGKCQTVLCRNGKPLSLSRSYTMSCEEERKRIKQHKAIITEDGKVNGVTESTRILGYTFLHPSVVPRPHVQSVLLTPQDEFFILGSKGLWDSLSIEEAVEAVRNVPDALAAAKKLCTLAQSYGCHDSISAVVVQLSVTEDSFCCCELSVGGSMPPPSPGIFPPSVSMVIKDRPSDGLGVPSSSSGMASEISSELSTSEMSSEVGSTASDEPPSGALSESSPAYPSEQRCMLHPVCLSNSFQRQLSSATFSSAFSDNGLDSDDEEPIEGVFSNGSRVEVEVDIHCSRAKEKERQQHLLQVPAEASDEGIVISANEDESGLSKKTDISAVGTIGRRRANGSVPPQERSHNVIEVATDAPLRKPGGYFAAPAQPDPDDQFIIPPELEEEVKEIMKHHQEQQQQQQQQQQQQQQQPPPPPQPPQAQAQAQAQAQRPFQMDHLPDCYDTPL", "length": 1696 }, "evidence": [ { "id": "F1NJB8", "url": "https://omabrowser.org/oma/group/F1NJB8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1NJB8", "url": "https://www.uniprot.org/uniprotkb/F1NJB8" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1NJB8", "url": "https://www.uniprot.org/uniprotkb/F1NJB8" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "F1NJB8", "url": "https://www.uniprot.org/uniprotkb/F1NJB8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "F1NJB8", "url": "https://www.uniprot.org/uniprotkb/F1NJB8" } ], "pmid": "" }, { "name": "protein serine/threonine phosphatase activity", "id": "GO:0004722", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004722", "evidence": [ { "database": "UniProtKB", "id": "F1NJB8", "url": "https://www.uniprot.org/uniprotkb/F1NJB8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 7, "go_terms": [ { "name": "apoptotic process", "id": "GO:0006915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006915", "evidence": [ { "database": "UniProtKB", "id": "F1NJB8", "url": "https://www.uniprot.org/uniprotkb/F1NJB8" } ], "pmid": "" }, { "name": "regulation of p38MAPK cascade", "id": "GO:1900744", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1900744", "evidence": [ { "database": "UniProtKB", "id": "F1NJB8", "url": "https://www.uniprot.org/uniprotkb/F1NJB8" } ], "pmid": "" }, { "name": "intracellular signal transduction", "id": "GO:0035556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035556", "evidence": [ { "database": "UniProtKB", "id": "F1NJB8", "url": "https://www.uniprot.org/uniprotkb/F1NJB8" } ], "pmid": "" }, { "name": "regulation of T cell anergy", "id": "GO:0002667", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002667", "evidence": [ { "database": "UniProtKB", "id": "F1NJB8", "url": "https://www.uniprot.org/uniprotkb/F1NJB8" } ], "pmid": "" }, { "name": "regulation of apoptotic process", "id": "GO:0042981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042981", "evidence": [ { "database": "UniProtKB", "id": "F1NJB8", "url": "https://www.uniprot.org/uniprotkb/F1NJB8" } ], "pmid": "" }, { "name": "negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction", "id": "GO:0051898", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051898", "evidence": [ { "database": "UniProtKB", "id": "F1NJB8", "url": "https://www.uniprot.org/uniprotkb/F1NJB8" } ], "pmid": "" }, { "name": "regulation of JNK cascade", "id": "GO:0046328", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046328", "evidence": [ { "database": "UniProtKB", "id": "F1NJB8", "url": "https://www.uniprot.org/uniprotkb/F1NJB8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1259, "end_pos": 1261, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1270, "end_pos": 1272, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1348, "end_pos": 1350, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1403, "end_pos": 1405, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1464, "end_pos": 1466, "annotation": "n_glycosylation_sequon" }, { "start_pos": 467, "end_pos": 469, "annotation": "n_glycosylation_sequon" }, { "start_pos": 544, "end_pos": 546, "annotation": "n_glycosylation_sequon" }, { "start_pos": 567, "end_pos": 569, "annotation": "n_glycosylation_sequon" }, { "start_pos": 74, "end_pos": 76, "annotation": "n_glycosylation_sequon" }, { "start_pos": 786, "end_pos": 788, "annotation": "n_glycosylation_sequon" }, { "start_pos": 839, "end_pos": 841, "annotation": "n_glycosylation_sequon" }, { "start_pos": 870, "end_pos": 872, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "20629", "name": "", "equation": "O-phospho-L-seryl-[protein] + H2O = L-seryl-[protein] + phosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V1AB34-1", "A0A1D5PI23-1", "A0A8V0ZW37-1", "P62207-1", "F1P225-1", "P0C597-1", "P48463-1", "Q9PTJ6-1", "Q9PW71-1", "A0A8V0Z2T2-1", "A0A8V0ZYK3-1", "Q5ZJJ8-1", "Q5ZJQ7-1", "Q9YHA0-1", "A0A1D5PJC6-1", "A0A8V0XTW9-1", "A0A8V0XLK8-1", "A0A8V0Y1D0-1", "A0A8V0ZMU4-1", "A0A8V0ZMX1-1", "A0A8V0ZQ53-1", "A0A8V0ZFN2-1", "A0A8V0ZPJ8-1", "A0A8V0ZWA8-1", "A0A8V1A8D0-1", "E1BTX9-1", "E1BRQ8-1", "A0A8V0ZJ28-1", "A0A8V0XYX4-1", "A0A8V0ZE41-1", "A0A8V0X9H5-1", "E1BYA9-1", "A0A8V0ZXB3-1", "F1NXH3-1", "A0A1D5P5S2-1", "F1NC58-1", "A0A8V0ZA69-1", "A0A8V1A6D3-1", "F1N842-1", "A0A8V0YC26-1", "A0A8V0ZND8-1", "A0A8V0ZS02-1", "A0A8V1AKZ7-1", "A0A8V1AK42-1", "A0A8V0XYE1-1", "F1NJB8-1", "Q5F3Z7-1" ], "evidence": [ { "id": "20629", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/20629" } ] }, { "id": "47004", "name": "", "equation": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0Y3H9-1", "A0A1D5PI23-1", "P62207-1", "A0A8V0ZIN0-1", "F1P225-1", "E1BVM8-1", "A0A8V1ANF4-1", "A0A1D5P5S2-1", "P0C597-1", "P48463-1", "Q9PTJ6-1", "Q9PW71-1", "A0A8V0Z2T2-1", "A0A8V0ZYK3-1", "Q5ZJJ8-1", "Q5ZJQ7-1", "Q9YHA0-1", "F1NCC5-1", "A0A1D5PJC6-1", "E1BTX9-1", "A0A8V0XTW9-1", "A0A8V0XYX4-1", "A0A8V0XLK8-1", "A0A8V0Y1D0-1", "A0A8V0Z256-1", "A0A8V0ZE41-1", "A0A8V0ZMU4-1", "A0A8V0ZMX1-1", "A0A8V0ZQ53-1", "A0A8V0ZPJ8-1", "A0A8V0ZWA8-1", "A0A8V0ZU36-1", "E1BRQ8-1", "A0A8V1A8D0-1", "A0A8V0ZJ28-1", "A0A8V0X9H5-1", "A0A8V1AB34-1", "E1BYA9-1", "A0A8V0ZXB3-1", "A0A8V0ZFN2-1", "F1NXH3-1", "A0A8V0ZW37-1", "A0A8V0ZA69-1", "A0A8V1A6D3-1", "F1N842-1", "A0A8V0YC26-1", "A0A8V0XYE1-1", "F1NJB8-1", "A0A8V0ZND8-1", "A0A8V0ZS02-1", "A0A8V1AKZ7-1", "A0A8V1AK42-1", "Q5F3Z7-1" ], "evidence": [ { "id": "47004", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/47004" } ] }, { "id": "R-GGA-199425", "name": "PHLPP dephosphorylates S473 in AKT", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [ "R-GGA-198356" ], "output_participant_list": [ "R-GGA-198634" ], "enzyme_list": [ "F1NJB8-1", "A0A8V0XYE1-1", "A0A3Q2U4X3-1" ], "evidence": [ { "id": "R-GGA-199425", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-199425" } ] } ], "reaction_participants": [ { "participant_id": "R-GGA-198356", "participant_name": "phospho-p-T308,S473-AKT1 [cytosol]", "crossref": [ { "id": "A0A8V0Z0D0", "database": "UniProt", "url": "" }, { "id": "ENSGALG00010017364", "database": "ENSEMBL", "url": "" }, { "id": "ENSGALP00010024506", "database": "ENSEMBL", "url": "" }, { "id": "ENSGALT00010041894", "database": "ENSEMBL", "url": "" } ] }, { "participant_id": "R-GGA-198634", "participant_name": "phospho-p-T308-AKT1 [cytosol]", "crossref": [ { "id": "ENSGALT00010041894", "database": "ENSEMBL", "url": "" }, { "id": "ENSGALG00010017364", "database": "ENSEMBL", "url": "" }, { "id": "A0A8V0Z0D0", "database": "UniProt", "url": "" }, { "id": "ENSGALP00010024506", "database": "ENSEMBL", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A0A1D5P5S2", "gene_name": "DUSP5", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A1D5P5S2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P5S2" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A1D5P5S2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P5S2" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A1D5P5S2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P5S2" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A1D5P5S2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P5S2" } ] } ] }, { "uniprot_ac": "A0A1D5PI23", "gene_name": "DUSP3", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A1D5PI23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PI23" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A1D5PI23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PI23" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A1D5PI23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PI23" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A1D5PI23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PI23" } ] } ] }, { "uniprot_ac": "A0A1D5PJC6", "gene_name": "CPPED1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A1D5PJC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PJC6" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A1D5PJC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PJC6" } ] } ] }, { "uniprot_ac": "A0A3Q2U4X3", "gene_name": "AKT1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q2U4X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U4X3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q2U4X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U4X3" } ] } ] }, { "uniprot_ac": "A0A8V0X9H5", "gene_name": "PPM1L", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0X9H5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X9H5" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0X9H5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X9H5" } ] } ] }, { "uniprot_ac": "A0A8V0XLK8", "gene_name": "PPEF2", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0XLK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XLK8" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0XLK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XLK8" } ] } ] }, { "uniprot_ac": "A0A8V0XTW9", "gene_name": "PPP3CA", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0XTW9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XTW9" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0XTW9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XTW9" } ] } ] }, { "uniprot_ac": "A0A8V0XYE1", "gene_name": "PHLPP2", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0XYE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XYE1" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0XYE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XYE1" } ] } ] }, { "uniprot_ac": "A0A8V0XYX4", "gene_name": "DUSP1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0XYX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XYX4" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0XYX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XYX4" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0XYX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XYX4" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0XYX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XYX4" } ] } ] }, { "uniprot_ac": "A0A8V0Y1D0", "gene_name": "CTDP1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0Y1D0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y1D0" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0Y1D0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y1D0" } ] } ] }, { "uniprot_ac": "A0A8V0Y3H9", "gene_name": "PPP2CB", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0Y3H9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y3H9" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0Y3H9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y3H9" } ] } ] }, { "uniprot_ac": "A0A8V0YC26", "gene_name": "DUSP19", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0YC26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC26" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0YC26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC26" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0YC26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC26" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0YC26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC26" } ] } ] }, { "uniprot_ac": "A0A8V0Z256", "gene_name": "CDKN3", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0Z256", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z256" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0Z256", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z256" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0Z256", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z256" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0Z256", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z256" } ] } ] }, { "uniprot_ac": "A0A8V0Z2T2", "gene_name": "DUSP26", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0Z2T2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2T2" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0Z2T2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2T2" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0Z2T2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2T2" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0Z2T2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2T2" } ] } ] }, { "uniprot_ac": "A0A8V0ZA69", "gene_name": "PGAM5", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZA69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA69" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0ZA69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA69" } ] } ] }, { "uniprot_ac": "A0A8V0ZE41", "gene_name": "PPM1B", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZE41", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE41" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0ZE41", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE41" } ] } ] }, { "uniprot_ac": "A0A8V0ZFN2", "gene_name": "CTDSP1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZFN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFN2" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0ZFN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFN2" } ] } ] }, { "uniprot_ac": "A0A8V0ZIN0", "gene_name": "SSH1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZIN0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIN0" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0ZIN0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIN0" } ] } ] }, { "uniprot_ac": "A0A8V0ZJ28", "gene_name": "PTEN", "activity": [ { "ec_number": "3.1.3.67", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + H2O = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + phosphate.", "evidence": [ { "id": "A0A8V0ZJ28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ28" } ] }, { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZJ28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ28" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZJ28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ28" } ] }, { "ec_number": "3.1.3.67", "activity": "", "evidence": [ { "id": "A0A8V0ZJ28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ28" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0ZJ28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ28" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0ZJ28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ28" } ] } ] }, { "uniprot_ac": "A0A8V0ZMU4", "gene_name": "DUSP13", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZMU4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMU4" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZMU4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMU4" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0ZMU4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMU4" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0ZMU4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMU4" } ] } ] }, { "uniprot_ac": "A0A8V0ZMX1", "gene_name": "RPAP2", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZMX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMX1" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0ZMX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMX1" } ] } ] }, { "uniprot_ac": "A0A8V0ZND8", "gene_name": "PTPMT1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZND8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZND8" } ] }, { "ec_number": "3.1.3.27", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycero-3'-phosphate) + H2O = a 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) + phosphate.", "evidence": [ { "id": "A0A8V0ZND8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZND8" } ] }, { "ec_number": "3.1.3.27", "activity": "", "evidence": [ { "id": "A0A8V0ZND8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZND8" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0ZND8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZND8" } ] } ] }, { "uniprot_ac": "A0A8V0ZPJ8", "gene_name": "LOC100857573", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZPJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPJ8" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZPJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPJ8" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0ZPJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPJ8" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0ZPJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPJ8" } ] } ] }, { "uniprot_ac": "A0A8V0ZQ53", "gene_name": "DUSP29", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZQ53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ53" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZQ53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ53" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0ZQ53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ53" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0ZQ53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ53" } ] } ] }, { "uniprot_ac": "A0A8V0ZS02", "gene_name": "PPM1F", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZS02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS02" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0ZS02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS02" } ] } ] }, { "uniprot_ac": "A0A8V0ZU36", "gene_name": "SSH3", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZU36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU36" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0ZU36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU36" } ] } ] }, { "uniprot_ac": "A0A8V0ZW37", "gene_name": "CDC14A", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZW37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZW37" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0ZW37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZW37" } ] } ] }, { "uniprot_ac": "A0A8V0ZWA8", "gene_name": "PPP1CA", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZWA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWA8" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0ZWA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWA8" } ] } ] }, { "uniprot_ac": "A0A8V0ZXB3", "gene_name": "DUSP28", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZXB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXB3" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZXB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXB3" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0ZXB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXB3" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0ZXB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXB3" } ] } ] }, { "uniprot_ac": "A0A8V0ZYK3", "gene_name": "PPP1CC", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZYK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZYK3" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0ZYK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZYK3" } ] } ] }, { "uniprot_ac": "A0A8V1A6D3", "gene_name": "DUSP8", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V1A6D3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6D3" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V1A6D3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6D3" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V1A6D3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6D3" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V1A6D3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6D3" } ] } ] }, { "uniprot_ac": "A0A8V1A8D0", "gene_name": "PPTC7", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V1A8D0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8D0" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V1A8D0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8D0" } ] } ] }, { "uniprot_ac": "A0A8V1AB34", "gene_name": "CTDSPL", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V1AB34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AB34" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V1AB34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AB34" } ] } ] }, { "uniprot_ac": "A0A8V1AK42", "gene_name": "DUSP23", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V1AK42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AK42" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V1AK42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AK42" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V1AK42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AK42" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V1AK42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AK42" } ] } ] }, { "uniprot_ac": "A0A8V1AKZ7", "gene_name": "PPM1E", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V1AKZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKZ7" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V1AKZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKZ7" } ] } ] }, { "uniprot_ac": "A0A8V1ANF4", "gene_name": "SSH2", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V1ANF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANF4" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V1ANF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANF4" } ] } ] }, { "uniprot_ac": "E1BRQ8", "gene_name": "DUSP15", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "E1BRQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BRQ8" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "E1BRQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BRQ8" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "E1BRQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BRQ8" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "E1BRQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BRQ8" } ] } ] }, { "uniprot_ac": "E1BTX9", "gene_name": "PPEF1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "E1BTX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BTX9" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "E1BTX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BTX9" } ] } ] }, { "uniprot_ac": "E1BVM8", "gene_name": "PPM1A", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "E1BVM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BVM8" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "E1BVM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BVM8" } ] } ] }, { "uniprot_ac": "E1BYA9", "gene_name": "ILKAP", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "E1BYA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BYA9" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "E1BYA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BYA9" } ] } ] }, { "uniprot_ac": "F1N842", "gene_name": "DUSP12", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F1N842", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N842" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1N842", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N842" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "F1N842", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N842" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1N842", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N842" } ] } ] }, { "uniprot_ac": "F1NC58", "gene_name": "PDXP", "activity": [ { "ec_number": "3.1.3.74", "activity": "pyridoxal 5'-phosphate + H2O = pyridoxal + phosphate.", "evidence": [ { "id": "F1NC58", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NC58" } ] }, { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F1NC58", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NC58" } ] }, { "ec_number": "3.1.3.74", "activity": "", "evidence": [ { "id": "F1NC58", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NC58" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "F1NC58", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NC58" } ] } ] }, { "uniprot_ac": "F1NCC5", "gene_name": "DUSP4", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F1NCC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCC5" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1NCC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCC5" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1NCC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCC5" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "F1NCC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCC5" } ] } ] }, { "uniprot_ac": "F1NJB8", "gene_name": "PHLPP1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F1NJB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NJB8" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "F1NJB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NJB8" } ] } ] }, { "uniprot_ac": "F1NXH3", "gene_name": "DUSP10", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F1NXH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NXH3" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1NXH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NXH3" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1NXH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NXH3" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "F1NXH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NXH3" } ] } ] }, { "uniprot_ac": "F1P225", "gene_name": "LOC423731", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F1P225", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P225" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1P225", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P225" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1P225", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P225" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "F1P225", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P225" } ] } ] }, { "uniprot_ac": "P0C597", "gene_name": "DUSP29", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P0C597", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P0C597" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P0C597", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P0C597" } ] } ] }, { "uniprot_ac": "P48463", "gene_name": "PPP2CA", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P48463", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48463" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P48463", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48463" } ] } ] }, { "uniprot_ac": "P62207", "gene_name": "PPP1CB", "activity": [ { "ec_number": "3.1.3.53", "activity": "O-phospho-L-threonyl-[myosin light chain] + H2O = L-threonyl-[myosin light chain] + phosphate.", "evidence": [ { "id": "P62207", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P62207" } ] }, { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P62207", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P62207" } ] }, { "ec_number": "3.1.3.53", "activity": "", "evidence": [ { "id": "P62207", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P62207" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P62207", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P62207" } ] } ] }, { "uniprot_ac": "Q5F3Z7", "gene_name": "CTDSPL2", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q5F3Z7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F3Z7" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q5F3Z7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F3Z7" } ] } ] }, { "uniprot_ac": "Q5ZJJ8", "gene_name": "UBLCP1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q5ZJJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJJ8" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q5ZJJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJJ8" } ] } ] }, { "uniprot_ac": "Q5ZJQ7", "gene_name": "SSU72", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q5ZJQ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJQ7" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q5ZJQ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJQ7" } ] } ] }, { "uniprot_ac": "Q9PTJ6", "gene_name": "NFI1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q9PTJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9PTJ6" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q9PTJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9PTJ6" } ] } ] }, { "uniprot_ac": "Q9PW71", "gene_name": "DUSP4", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q9PW71", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9PW71" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q9PW71", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9PW71" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q9PW71", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9PW71" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q9PW71", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9PW71" } ] } ] }, { "uniprot_ac": "Q9YHA0", "gene_name": "EYA1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q9YHA0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9YHA0" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q9YHA0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9YHA0" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q9YHA0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9YHA0" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q9YHA0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9YHA0" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "3.1.3.16", "ec_name": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "3.1.3.16", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.16" }, { "id": "3.1.3.16", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=3.1.3.16" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1259, "end_pos": 1261 }, { "start_pos": 1270, "end_pos": 1272 }, { "start_pos": 1348, "end_pos": 1350 }, { "start_pos": 1403, "end_pos": 1405 }, { "start_pos": 1464, "end_pos": 1466 }, { "start_pos": 467, "end_pos": 469 }, { "start_pos": 544, "end_pos": 546 }, { "start_pos": 567, "end_pos": 569 }, { "start_pos": 74, "end_pos": 76 }, { "start_pos": 786, "end_pos": 788 }, { "start_pos": 839, "end_pos": 841 }, { "start_pos": 870, "end_pos": 872 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1NGB8-1", "uniprot_ac": "F1NGB8", "uniprot_id": "F1NGB8_CHICK", "mass": { "chemical_mass": 105146.0, "monoisotopic_mass": 105146.0 }, "refseq": { "ac": "XP_015140673", "name": "exostosin-like 3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015140673" }, "gene_names": [ { "name": "EXTL3", "type": "recommended", "evidence": [ { "id": "F1NGB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NGB8" } ] }, { "name": "EXTL3", "type": "synonym", "evidence": [ { "id": "XP_015140673", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015140673" } ] } ], "protein_names": [ { "name": "Exostosin-like 3", "type": "recommended", "evidence": [ { "id": "F1NGB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NGB8/entry#names_and_taxonomy" } ] }, { "name": "2.4.1.223", "type": "synonym", "evidence": [ { "id": "F1NGB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NGB8/entry#names_and_taxonomy" } ] }, { "name": "Glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase", "type": "synonym", "evidence": [ { "id": "F1NGB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NGB8/entry#names_and_taxonomy" } ] }, { "name": "Multiple exostosis-like protein 3", "type": "synonym", "evidence": [ { "id": "F1NGB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NGB8/entry#names_and_taxonomy" } ] }, { "name": "exostosin-like 3", "type": "synonym", "evidence": [ { "id": "XP_015140673", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015140673" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052534.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015140673", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015140673" } ] }, { "annotation": "Glycosyltransferase which regulates the biosynthesis of heparan sulfate (HS). Initiates HS synthesis by transferring the first N-acetyl-alpha-D-glucosamine (alpha-GlcNAc) residue (GlcNAcT-I activity) to the tetrasaccharide linker (GlcA-Gal-Gal-Xyl-)Ser core linker. May also transfer alpha-GlcNAc residues during HS elongation (GlcNAcT-II activity). Lacks glucuronyl transferase II (GlcAT-II) activity. Important for both skeletal development and hematopoiesis, through the formation of HS proteoglycans (HSPGs). Through the synthesis of HS, regulates postnatal pancreatic islet maturation and insulin secretion.", "evidence": [ { "database": "UniProtKB", "id": "F1NGB8", "url": "https://www.uniprot.org/uniprotkb/F1NGB8#function" }, { "database": "UniProtKB", "id": "ARBA00058474", "url": "https://www.uniprot.org/uniprotkb/ARBA00058474#function" } ] }, { "annotation": "Receptor for REG3A, REG3B and REG3G, induces the activation of downstream signaling pathways such as PI3K-AKT or RAS-RAF-MEK-ERK signaling pathway. Required for the function of REG3A in regulating keratinocyte proliferation and differentiation. Required for the inhibition of skin inflammation mediated by REG3A through the activation of PI3K-AKT-STAT3 pathway. Required for the function of REG3A and REG3G in glucose tolerance in pancreas. Expressed in microglia, is activated by nociceptor-derived REG3G in response to endotoxins, leading to the inhibition of kynurenine pathway to prevent endotoxic death.", "evidence": [ { "database": "UniProtKB", "id": "F1NGB8", "url": "https://www.uniprot.org/uniprotkb/F1NGB8#function" }, { "database": "UniProtKB", "id": "ARBA00058348", "url": "https://www.uniprot.org/uniprotkb/ARBA00058348#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NGB8", "url": "https://www.uniprot.org/uniprotkb/F1NGB8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "EXTL3", "url": "https://www.uniprot.org/uniprotkb/F1NGB8", "locus": { "chromosome": "3", "start_pos": 105822513, "end_pos": 105796017, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010010953", "url": "https://www.ensembl.org/id/ENSGALG00010010953" } ] } } ], "crossref": [ { "id": "F1NGB8", "url": "https://alphafold.ebi.ac.uk/entry/F1NGB8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000016630", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000016630", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "422022", "url": "https://www.ncbi.nlm.nih.gov/gene/422022", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004263", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004263", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015338", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015338", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029044", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029044", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040911", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040911", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:422022", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422022", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "KFMGSHT", "url": "https://omabrowser.org/oma/group/KFMGSHT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YB35", "url": "https://www.orthodb.org/?gene=A0A8V0YB35", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NGB8", "url": "https://www.orthodb.org/?gene=F1NGB8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48261", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48261", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR48261:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48261:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03016", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03016", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF09258", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09258", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-2022928", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2022928", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_015140673", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015140673", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "16221", "url": "https://www.rhea-db.org/rhea/16221", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YB35", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB35", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YB35-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB35-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NGB8", "url": "https://www.uniprot.org/uniprotkb/F1NGB8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NGB8-1", "url": "https://www.uniprot.org/uniprotkb/F1NGB8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTGYTMLRNGGVGNGGQPWLLRWSSRIRLTWLSFILFVILVFFPLIGHYYLTTIDDADDAGKRIFGPRTGNELCEVKHVQDLCRIRESVSEELLQLEAKRQELNSEIAKLNLKIEACKKSIENAKQDLLQLKNVISQTEHSYKELMAQNQPKLSLPIRLLPDKDDATFPLPKSNRNCRLHNCFDYSRCPLTSGFPVYVYNSDDYPFGSSLDPLIKQAFEATVRTNVYVTENANIACVYIILVGEMQEPVMPKPTELEQQLHSLPYWRTDGHNHLIINLSRKSETQNFLYNISTGRAMLAQSTFYDVQYRPGFDIVVSPLVHAMSEPNFLEIPPQVPVKRKYLFSFQGEKIESLRSSLQEVRSFEEEIEGNAPADYDDRIITTLKAVQDSKLDFVLVEFTCKNQPKASLPTEWALCGERDDRLELLKLSTFALIITPGDTRLVISAGCAMRLFEALEVGAIPVVLGEQVQLPYNDVIRWNEAALIIPKPRITEVHFLLRSISDNDLLAMRRQGRFLWETYFSTSDNVFSTVLAIIRTRIQIPAAPIREETAVEIPHRSGKAAGTDPNMADNGDLDLGPVETEPPYASPKYLRNFTLTAMDIYRNWNSAPGPFHLFPYTPFDPVLPSEAKFLGSGTGFRPIGGGAGGSGKEFQAALGGNVPREQFTVVMLTYEREEVLMNSLERLNGLPYLNKVVVVWNSPKLPSEDLLWPDIGVPIMVVRTEKNSLNNRFLPWDEIETEAILSIDDDAHLRHDEIMFGFRVWREARDRIVGFPGRYHAWDIPHQSWLYNSNYSCELSMVLTGAAFFHKYYAYLYSYVMPQAIRDMVDEYINCEDIAMNFLVSHLTRKPPIKVTSRWTFRCPGCPQALSHDDSHFHERHKCINFFVKVYGYMPLLYTQFRVDSVLFKTRLPHDKTKCFKFI", "length": 919, "header": "tr|F1NGB8-1|F1NGB8_CHICK Isoform 1 of Exostosin-like 3 OS=Gallus gallus OX=9031 GN=EXTL3 PE=1 SV=2 CANONICAL=F1NGB8-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YB35-1", "url": "https://www.uniprot.org/uniprotkb/F1NGB8/entry#A0A8V0YB35-1", "sequence": { "sequence": "MTGYTMLRNGGVGNGGQPWLLRWSSRIRLTWLSFILFVILVFFPLIGHYYLTTIDDADDAGKRIFGPRTGNELCEVKHVQDLCRIRESVSEELLQLEAKRQELNSEIAKLNLKIEACKKSIENAKQDLLQLKNVISQTEHSYKELMAQNQPKLSLPIRLLPDKDDATFPLPKSNRNCRLHNCFDYSRCPLTSGFPVYVYNSDDYPFGSSLDPLIKQAFEATVRTNVYVTENANIACVYIILVGEMQEPVMPKPTELEQQLHSLPYWRTDGHNHLIINLSRKSETQNFLYNISTGRAMLAQSTFYDVQYRPGFDIVVSPLVHAMSEPNFLEIPPQVPVKRKYLFSFQGEKIESLRSSLQEVRSFEEEIEGNAPADYDDRIITTLKAVQDSKLDFVLVEFTCKNQPKASLPTEWALCGERDDRLELLKLSTFALIITPGDTRLVISAGCAMRLFEALEVGAIPVVLGEQVQLPYNDVIRWNEAALIIPKPRITEVHFLLRSISDNDLLAMRRQGRFLWETYFSTSDNVFSTVLAIIRTRIQIPAAPIREETAVEIPHRSGKAAGTDPNMADNGDLDLGPVETEPPYASPKYLRNFTLTAMDIYRNWNSAPGPFHLFPYTPFDPVLPSEAKFLGSGTGFRPIGGGAGGSGKEFQAALGGNVPREQFTVVMLTYEREEVLMNSLERLNGLPYLNKVVVVWNSPKLPSEDLLWPDIGVPIMVVRTEKNSLNNRFLPWDEIETEAILSIDDDAHLRHDEIMFGFRVWREARDRIVGFPGRYHAWDIPHQSWLYNSNYSCELSMVLTGAAFFHKVRYCRITEYPKLKGTHKDHQVHNCSSMVSLVLSLPSQTNWSSCGCGGFVFKEETAAHCSFSLARSIQKH", "length": 876, "header": "tr|A0A8V0YB35-1|A0A8V0YB35_CHICK Computationally mapped isoform of Exostosin like glycosyltransferase 3 OS=Gallus gallus OX=9031 GN=EXTL3 PE=1 SV=1 CANONICAL=F1NGB8-1" }, "locus": { "chromosome": "3", "start_pos": 105820259, "end_pos": 105796216, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026226.1", "url": "https://www.ensembl.org/id/ENSGALT00010026226.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010014850.1", "url": "https://www.ensembl.org/id/ENSGALP00010014850.1" } ] } }, { "isoform_ac": "F1NGB8-1", "url": "https://www.uniprot.org/uniprotkb/F1NGB8/entry#F1NGB8-1", "sequence": { "sequence": "MTGYTMLRNGGVGNGGQPWLLRWSSRIRLTWLSFILFVILVFFPLIGHYYLTTIDDADDAGKRIFGPRTGNELCEVKHVQDLCRIRESVSEELLQLEAKRQELNSEIAKLNLKIEACKKSIENAKQDLLQLKNVISQTEHSYKELMAQNQPKLSLPIRLLPDKDDATFPLPKSNRNCRLHNCFDYSRCPLTSGFPVYVYNSDDYPFGSSLDPLIKQAFEATVRTNVYVTENANIACVYIILVGEMQEPVMPKPTELEQQLHSLPYWRTDGHNHLIINLSRKSETQNFLYNISTGRAMLAQSTFYDVQYRPGFDIVVSPLVHAMSEPNFLEIPPQVPVKRKYLFSFQGEKIESLRSSLQEVRSFEEEIEGNAPADYDDRIITTLKAVQDSKLDFVLVEFTCKNQPKASLPTEWALCGERDDRLELLKLSTFALIITPGDTRLVISAGCAMRLFEALEVGAIPVVLGEQVQLPYNDVIRWNEAALIIPKPRITEVHFLLRSISDNDLLAMRRQGRFLWETYFSTSDNVFSTVLAIIRTRIQIPAAPIREETAVEIPHRSGKAAGTDPNMADNGDLDLGPVETEPPYASPKYLRNFTLTAMDIYRNWNSAPGPFHLFPYTPFDPVLPSEAKFLGSGTGFRPIGGGAGGSGKEFQAALGGNVPREQFTVVMLTYEREEVLMNSLERLNGLPYLNKVVVVWNSPKLPSEDLLWPDIGVPIMVVRTEKNSLNNRFLPWDEIETEAILSIDDDAHLRHDEIMFGFRVWREARDRIVGFPGRYHAWDIPHQSWLYNSNYSCELSMVLTGAAFFHKYYAYLYSYVMPQAIRDMVDEYINCEDIAMNFLVSHLTRKPPIKVTSRWTFRCPGCPQALSHDDSHFHERHKCINFFVKVYGYMPLLYTQFRVDSVLFKTRLPHDKTKCFKFI", "length": 919, "header": "tr|F1NGB8-1|F1NGB8_CHICK Isoform 1 of Exostosin-like 3 OS=Gallus gallus OX=9031 GN=EXTL3 PE=1 SV=2 CANONICAL=F1NGB8-1" }, "locus": { "chromosome": "3", "start_pos": 105822218, "end_pos": 105796216, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026227.1", "url": "https://www.ensembl.org/id/ENSGALT00010026227.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010014851.1", "url": "https://www.ensembl.org/id/ENSGALP00010014851.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "gga:422022", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422022", "resource": "KEGG Pathway" }, { "id": "R-GGA-2022928", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2022928", "resource": "Reactome", "description": "HS-GAG biosynthesis" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A9J7F2J4-1", "protein_name": "Exostosin-like 3", "gene_name": "Extl3", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MTGYTMLRNGGVGNGGQTCMLRWSNRIRLTWLSFTLFIILVFFPLIAHYYLTTLDEADEAGKRIFGPRAGNELCEVKHVLDLCRIRESVSEELLQLEAKRQELNSEIAKLNLKIEACKKSIENAKQDLLQLKNVISQTEHSYKELMAQNQPKLSLPIRLLPEKDDAGLPPPKVTRGCRLHNCFDYSRCPLTSGFPVYVYDSDQFAFGSYLDPLVKQAFQATVRANVYVTENAAIACLYVVLVGEMQEPVVVRPADLEKQLYSLPHWRTDGHNHVIINLSRKSDTQNLLYNVSTGRAMVAQSTFYAAQYRPGFDLVVSPLVHAMSEPNFMEIPPQVPVKRKYLFTFQGEKIESLRSSLQEARSFEEEMEGDPPADYDDRIIATLKAVQDSKLDQVLVEFTCKNQPKPSLPTEWALCGEREDRLELLKLSTFALIITPGDPHLVISSGCATRLFEALEVGAVPVVLGQQVQLPYHGMLEWNEAALVVPKPRVTEVHFLLRSLSDSDLLAMRRQGRFLWETYFSTADSIFNTVLAMIRTRIQIPAAPIREEVAAEIPHRSGKAAGTDPNMADNGDLDLGPVETEPPYASPKYLRNFTLTVTDCYRSWNSAPGPFHLFPHTPFDPVLPSEAKFLGSGTGFRPIGGGAGGSGKEFQAALGGNVQREQFTVVMLTYEREEVLMNSLERLNGLPYLNKVVVVWNSPKLPSEDLLWPDIGVPIMVVRTEKNSLNNRFLPWNEIETEAILSIDDDAHLRHDEIMFGFRVWREARDRIVGFPGRYHAWDIPHQSWLYNSNYSCELSMVLTGAAFFHKYYAYLYSYVMPQAIRDMVDEYINCEDIAMNFLVSHITRKPPIKINTTWRLVWTSNIGHIRLCCLLNMVTWKDPSVTSRWTFRCPGCPQALSHDDSHFHERHKCINFFVKVYGYMPLLYTQFRVDSVLFKTRLPHDKTKCFKFI", "length": 950 }, "evidence": [ { "id": "F1NGB8", "url": "https://omabrowser.org/oma/group/F1NGB8/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "O43909-1", "protein_name": "Exostosin-like 3", "gene_name": "EXTL3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTGYTMLRNGGAGNGGQTCMLRWSNRIRLTWLSFTLFVILVFFPLIAHYYLTTLDEADEAGKRIFGPRVGNELCEVKHVLDLCRIRESVSEELLQLEAKRQELNSEIAKLNLKIEACKKSIENAKQDLLQLKNVISQTEHSYKELMAQNQPKLSLPIRLLPEKDDAGLPPPKATRGCRLHNCFDYSRCPLTSGFPVYVYDSDQFVFGSYLDPLVKQAFQATARANVYVTENADIACLYVILVGEMQEPVVLRPAELEKQLYSLPHWRTDGHNHVIINLSRKSDTQNLLYNVSTGRAMVAQSTFYTVQYRPGFDLVVSPLVHAMSEPNFMEIPPQVPVKRKYLFTFQGEKIESLRSSLQEARSFEEEMEGDPPADYDDRIIATLKAVQDSKLDQVLVEFTCKNQPKPSLPTEWALCGEREDRLELLKLSTFALIITPGDPRLVISSGCATRLFEALEVGAVPVVLGEQVQLPYQDMLQWNEAALVVPKPRVTEVHFLLRSLSDSDLLAMRRQGRFLWETYFSTADSIFNTVLAMIRTRIQIPAAPIREEAAAEIPHRSGKAAGTDPNMADNGDLDLGPVETEPPYASPRYLRNFTLTVTDFYRSWNCAPGPFHLFPHTPFDPVLPSEAKFLGSGTGFRPIGGGAGGSGKEFQAALGGNVPREQFTVVMLTYEREEVLMNSLERLNGLPYLNKVVVVWNSPKLPSEDLLWPDIGVPIMVVRTEKNSLNNRFLPWNEIETEAILSIDDDAHLRHDEIMFGFRVWREARDRIVGFPGRYHAWDIPHQSWLYNSNYSCELSMVLTGAAFFHKYYAYLYSYVMPQAIRDMVDEYINCEDIAMNFLVSHITRKPPIKVTSRWTFRCPGCPQALSHDDSHFHERHKCINFFVKVYGYMPLLYTQFRVDSVLFKTRLPHDKTKCFKFI", "length": 919 }, "evidence": [ { "id": "F1NGB8", "url": "https://omabrowser.org/oma/group/F1NGB8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9XZ08-1", "protein_name": "Exostosin-3", "gene_name": "botv", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MPPAYDLGHSGEAYQPLDTGSGGGNEACAPNSSSAQIRHSMGFRTSWMRQFRRYKLPMVLLMLLFLVSCLAYRILSVEQDAPPLDLHRSSPLLDAYEDFSAMRAGDLKMRIEEMVRIKSTVSVELRELESRRQKLQSDISQYNQKIEELKQELLREQTELERLKISVEQAQVAQREAVQRNTPDLALPRSLLPNTLPRKSNPITGGMAASCEMHNCFNHSRCSLTSGFPVYLYDPDEHSVQRKGYDIDGFLKTTLKQTLGYNAHIVKDPKHACIYLVLVGEALLEQDLLRNNRYAAQEAEHQQPSTPTLENDCPVDMEKLYSLPYWGGDGRNHVLLNLARRDLTSHRTNPLYRQNTMRAIVVQSAFEREQFRPGYDLIVPPILGPPGGDVWQECAEMVPARRKYLLTYQGELRPKQSSLNPLDAFILEHLADMAKGATQDQFVLQFQCVPATEQQEGDSLPDWTLCGSDSSRRQLLKDSTFSLILPPLNGRVSSTLMLARIYEALRSGAVPVILGADELRLPYAETVDWRRTALLLPKARITELHFLLRAVQDADLLLLRRQGRLIWERYLSSVQATVDTVIASLRDRLGIPPRPVPSVIAQSVFNSTFIPLKSDPPVGLDTEPEESLGPIEPPYPSPAFRRNYTILRMQAKEAWNDWLDPFYLYPQLPFDPALPSEAKFMGSHTGFRPIGKGLGGAGKEFGESLGGNYPREQFTIVMLTYEREQVLMDSLGRLYGLPYLHKVVVVWNSPKPPLDDLRWPDIGVPVAVLRAPRNSLNNRFLPFDVIETEAVLSVDDDAHLRHDEILFGFRVWREHRDRVVGFPGRYHAWDLGNPNGQWHYNSNYSCELSMVLTGAAFVHKYYLYLYTYHLPQAIRDKVDEYMNCEDIAMNFLVSHITRKPPVKVTSRWTFRCPGCPVSLSEDDTHFQERHKCINFFSRVFGYTPLLNTQYRADSILFKTRIPHDKQKCFKYI", "length": 972 }, "evidence": [ { "id": "F1NGB8", "url": "https://omabrowser.org/oma/group/F1NGB8/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "F1NGB8", "url": "https://www.uniprot.org/uniprotkb/F1NGB8" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "F1NGB8", "url": "https://www.uniprot.org/uniprotkb/F1NGB8" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F1NGB8", "url": "https://www.uniprot.org/uniprotkb/F1NGB8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "glycosyltransferase activity", "id": "GO:0016757", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016757", "evidence": [ { "database": "UniProtKB", "id": "F1NGB8", "url": "https://www.uniprot.org/uniprotkb/F1NGB8" } ], "pmid": "" }, { "name": "protein-hormone receptor activity", "id": "GO:0016500", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016500", "evidence": [ { "database": "UniProtKB", "id": "F1NGB8", "url": "https://www.uniprot.org/uniprotkb/F1NGB8" } ], "pmid": "" }, { "name": "magnesium ion binding", "id": "GO:0000287", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000287", "evidence": [ { "database": "UniProtKB", "id": "F1NGB8", "url": "https://www.uniprot.org/uniprotkb/F1NGB8" } ], "pmid": "" }, { "name": "glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity", "id": "GO:0001888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001888", "evidence": [ { "database": "UniProtKB", "id": "F1NGB8", "url": "https://www.uniprot.org/uniprotkb/F1NGB8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "heparan sulfate proteoglycan biosynthetic process", "id": "GO:0015012", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015012", "evidence": [ { "database": "UniProtKB", "id": "F1NGB8", "url": "https://www.uniprot.org/uniprotkb/F1NGB8" } ], "pmid": "" }, { "name": "negative regulation of keratinocyte differentiation", "id": "GO:0045617", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045617", "evidence": [ { "database": "UniProtKB", "id": "F1NGB8", "url": "https://www.uniprot.org/uniprotkb/F1NGB8" } ], "pmid": "" }, { "name": "positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction", "id": "GO:0051897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051897", "evidence": [ { "database": "UniProtKB", "id": "F1NGB8", "url": "https://www.uniprot.org/uniprotkb/F1NGB8" } ], "pmid": "" }, { "name": "positive regulation of keratinocyte proliferation", "id": "GO:0010838", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010838", "evidence": [ { "database": "UniProtKB", "id": "F1NGB8", "url": "https://www.uniprot.org/uniprotkb/F1NGB8" } ], "pmid": "" }, { "name": "negative regulation of inflammatory response to wounding", "id": "GO:0106015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0106015", "evidence": [ { "database": "UniProtKB", "id": "F1NGB8", "url": "https://www.uniprot.org/uniprotkb/F1NGB8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 277, "end_pos": 279, "annotation": "n_glycosylation_sequon" }, { "start_pos": 290, "end_pos": 292, "annotation": "n_glycosylation_sequon" }, { "start_pos": 592, "end_pos": 594, "annotation": "n_glycosylation_sequon" }, { "start_pos": 790, "end_pos": 792, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "16221", "name": "", "equation": "3-O-(beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl)-L-seryl-[protein] + UDP-N-acetyl-alpha-D-glucosamine = 3-O-(alpha-D-GlcNAc-(1->4)-beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl)-L-seryl-[protein] + UDP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0ZXC9-1", "F1NGB8-1" ], "evidence": [ { "id": "16221", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/16221" } ] }, { "id": "R-GGA-9953259", "name": "EXTL3 dimer transfers GlcNAc to the GAG linker", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "Golgi lumen, Golgi membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1NGB8-1", "A0A8V0ZXC9-1" ], "evidence": [ { "id": "R-GGA-9953259", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9953259" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A8V0ZXC9", "gene_name": "EXTL2", "activity": [ { "ec_number": "2.4.1.223", "activity": "3-O-(beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl)-L-seryl-[protein] + UDP-N-acetyl-alpha-D-glucosamine = 3-O-(alpha-D-GlcNAc-(1->4)-beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl)-L-seryl-[protein] + UDP + H(+).", "evidence": [ { "id": "A0A8V0ZXC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXC9" } ] }, { "ec_number": "2.4.1.223", "activity": "", "evidence": [ { "id": "A0A8V0ZXC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXC9" } ] } ] }, { "uniprot_ac": "F1NGB8", "gene_name": "EXTL3", "activity": [ { "ec_number": "2.4.1.223", "activity": "3-O-(beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl)-L-seryl-[protein] + UDP-N-acetyl-alpha-D-glucosamine = 3-O-(alpha-D-GlcNAc-(1->4)-beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl)-L-seryl-[protein] + UDP + H(+).", "evidence": [ { "id": "F1NGB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NGB8" } ] }, { "ec_number": "2.4.1.223", "activity": "", "evidence": [ { "id": "F1NGB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NGB8" } ] } ] } ], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1NGB8-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 919, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1NGB8-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1NGB8" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1NGB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NGB8" }, { "id": "PF03016", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03016" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Exostosin GT47", "eco_id": "ECO_0000259", "start_pos": 192, "end_pos": 500, "start_aa": "Ser", "end_aa": "Ile", "glycosite_overlap": "" }, { "evidence": [ { "id": "F1NGB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NGB8" }, { "id": "PF09258", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09258" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Glycosyl transferase 64", "eco_id": "ECO_0000259", "start_pos": 663, "end_pos": 904, "start_aa": "Phe", "end_aa": "Phe", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.4.1.223", "ec_name": "3-O-(beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl)-L-seryl-[protein] + UDP-N-acetyl-alpha-D-glucosamine = 3-O-(alpha-D-GlcNAc-(1->4)-beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl)-L-seryl-[protein] + UDP + H(+).", "evidence": [ { "id": "2.4.1.223", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.1.223" }, { "id": "2.4.1.223", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.4.1.223" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 277, "end_pos": 279 }, { "start_pos": 290, "end_pos": 292 }, { "start_pos": 592, "end_pos": 594 }, { "start_pos": 790, "end_pos": 792 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1NZA9-1", "uniprot_ac": "F1NZA9", "uniprot_id": "F1NZA9_CHICK", "mass": { "chemical_mass": 48941.0, "monoisotopic_mass": 48941.0 }, "refseq": { "ac": "XP_416450", "name": "polyglutamylase complex subunit TTLL1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_416450" }, "gene_names": [ { "name": "TTLL1", "type": "recommended", "evidence": [ { "id": "F1NZA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NZA9" } ] }, { "name": "TTLL1", "type": "synonym", "evidence": [ { "id": "XP_416450", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_416450" } ] } ], "protein_names": [ { "name": "Polyglutamylase complex subunit TTLL1", "type": "recommended", "evidence": [ { "id": "F1NZA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NZA9/entry#names_and_taxonomy" } ] }, { "name": "Tubulin polyglutamylase TTLL1", "type": "synonym", "evidence": [ { "id": "F1NZA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NZA9/entry#names_and_taxonomy" } ] }, { "name": "Tubulin polyglutamylase complex subunit 3", "type": "synonym", "evidence": [ { "id": "F1NZA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NZA9/entry#names_and_taxonomy" } ] }, { "name": "Tubulin--tyrosine ligase-like protein 1", "type": "synonym", "evidence": [ { "id": "F1NZA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NZA9/entry#names_and_taxonomy" } ] }, { "name": "polyglutamylase complex subunit TTLL1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_416450", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_416450" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Nov 16, 2006 this sequence version replaced XP_416450.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_416450", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_416450" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NZA9", "url": "https://www.uniprot.org/uniprotkb/F1NZA9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TTLL1", "url": "https://www.uniprot.org/uniprotkb/F1NZA9", "locus": { "chromosome": "1", "start_pos": 68553558, "end_pos": 68581512, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012193", "url": "https://www.ensembl.org/id/ENSGALG00010012193" } ] } } ], "crossref": [ { "id": "F1NZA9", "url": "https://alphafold.ebi.ac.uk/entry/F1NZA9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000014163", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000014163", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "418225", "url": "https://www.ncbi.nlm.nih.gov/gene/418225", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004344", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004344", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "DWNFYWS", "url": "https://omabrowser.org/oma/group/DWNFYWS/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YEL7", "url": "https://www.orthodb.org/?gene=A0A8V0YEL7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NZA9", "url": "https://www.orthodb.org/?gene=F1NZA9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12241", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12241", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12241:SF31", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12241:SF31", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03133", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03133", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_416450", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_416450", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "60148", "url": "https://www.rhea-db.org/rhea/60148", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YEL7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEL7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YEL7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEL7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NZA9", "url": "https://www.uniprot.org/uniprotkb/F1NZA9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NZA9-1", "url": "https://www.uniprot.org/uniprotkb/F1NZA9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAGKVKWVTDIEKSVLINNFEKRGWIQVAENEDWNFYWMSVQTIRNVFSVETGYRLSDDQIVNHFPNHYELTRKDLMVKNIKRYRKELEKEGSPLAEKDENGKYIYLDFVPVTFMLPADYNLFVEEFRKNPSSTWIMKPCGKAQGKGIFLINKLSQIKKWSRDSKTSSFVSQSSKEAYVISLYINNPLLIGGKKFDLRLYVLVSTYRPLRCYMYKLGFCRFCTVKYTPSTSELDNMFVHLTNVAIQKHGDDYNHIHGGKWTVSNLRLYLESTRGKEVTNKLFDEIHWIIVQSLKAVAPVMNNDKHCFECYGYDIIIDDKLKPWLIEVNASPSLTSSTANDRILKYNLINDTLNIAVPNGEIPDCKWNKSPPKEVLGNYEVLYDEEMAQSDGSDRDLRSRSGQSTGTKGNRGRDSGKPVLTTWK", "length": 423, "header": "tr|F1NZA9-1|F1NZA9_CHICK Isoform 1 of Polyglutamylase complex subunit TTLL1 OS=Gallus gallus OX=9031 GN=TTLL1 PE=3 SV=3 CANONICAL=F1NZA9-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YEL7-1", "url": "https://www.uniprot.org/uniprotkb/F1NZA9/entry#A0A8V0YEL7-1", "sequence": { "sequence": "MAGKVKWVTDIEKSVLINNFEKRGWIQVAENEDWNFYWMSVQTIRNVFSVETGYRLSDDQIVNHFPNHYELTRKDLMVKNIKRYRKELEKEGSPLAEKDENGKYIYLDFVPVTFMLPADYNLFVEEFRKNPSSTWIMKPCGKAQGKGIFLINKLSQIKKWSRDSKTSSFVSQSSKEAYVISLYINNPLLIGGKKFDLRLYVLVSTYRPLRCYMYKLGFCRFCTVKYTPSTSELDNMFVHLTNVAIQKHGDDYNHIHGGKWTVSNLRLYLESTRGKEVTNKLFDEIHWIIVQSLKAVAPVMNNDKHCFECYGYDIIIDDKLKPWLIEVNASPSLTSSTANDRILKYNLINDTLNIAVPNGEIPDCKWNKSPPKEVLGNYEVFVYLNVKSMGNVLHPEDNIQLLENGIP", "length": 407, "header": "tr|A0A8V0YEL7-1|A0A8V0YEL7_CHICK Computationally mapped isoform of Polyglutamylase complex subunit TTLL1 OS=Gallus gallus OX=9031 GN=TTLL1 PE=3 SV=1 CANONICAL=F1NZA9-1" }, "locus": { "chromosome": "1", "start_pos": 68577298, "end_pos": 68553766, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029234.1", "url": "https://www.ensembl.org/id/ENSGALT00010029234.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016959.1", "url": "https://www.ensembl.org/id/ENSGALP00010016959.1" } ] } }, { "isoform_ac": "F1NZA9-1", "url": "https://www.uniprot.org/uniprotkb/F1NZA9/entry#F1NZA9-1", "sequence": { "sequence": "MAGKVKWVTDIEKSVLINNFEKRGWIQVAENEDWNFYWMSVQTIRNVFSVETGYRLSDDQIVNHFPNHYELTRKDLMVKNIKRYRKELEKEGSPLAEKDENGKYIYLDFVPVTFMLPADYNLFVEEFRKNPSSTWIMKPCGKAQGKGIFLINKLSQIKKWSRDSKTSSFVSQSSKEAYVISLYINNPLLIGGKKFDLRLYVLVSTYRPLRCYMYKLGFCRFCTVKYTPSTSELDNMFVHLTNVAIQKHGDDYNHIHGGKWTVSNLRLYLESTRGKEVTNKLFDEIHWIIVQSLKAVAPVMNNDKHCFECYGYDIIIDDKLKPWLIEVNASPSLTSSTANDRILKYNLINDTLNIAVPNGEIPDCKWNKSPPKEVLGNYEVLYDEEMAQSDGSDRDLRSRSGQSTGTKGNRGRDSGKPVLTTWK", "length": 423, "header": "tr|F1NZA9-1|F1NZA9_CHICK Isoform 1 of Polyglutamylase complex subunit TTLL1 OS=Gallus gallus OX=9031 GN=TTLL1 PE=3 SV=3 CANONICAL=F1NZA9-1" }, "locus": { "chromosome": "1", "start_pos": 68577298, "end_pos": 68561068, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029229.1", "url": "https://www.ensembl.org/id/ENSGALT00010029229.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016954.1", "url": "https://www.ensembl.org/id/ENSGALP00010016954.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A8M1P2G8-1", "protein_name": "Polyglutamylase complex subunit TTLL1", "gene_name": "ttll1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAGKVKWVTDIEKSVLINNFEKRGWIQVTDSEDWNFYWMSIQTIRTVFSVDTGYRLTDDQMVNHFPNHYELTRKDLMIKNIKRYRRELEKENSALAEKDDSGKYIYLDFVPVTFMLPADYNLFVEEFRKSPSSTWIMKPCGKAQGKGIFLINKLSQIKKWSRDSRTSTFVAANSGKEAYVISLYIDNPLLIGGKKFDLRLYVLVTTYRPLKCYMYKLGFCRFCTVKYTPSTSELDNMFVHLTNVAIQKHGDDYNHVHGGKWTVSNLRLYLESTRGPDVTNHLFDQIHWIIVQSLKAVAPVMNNDKHCFECYGYDIIIDDRLKPWLIEVNASPSLTSSTANDRILKYNLINDTLNIVTPNAEIPDCRWNRSLPKEALGHYQVLYDEEQALSESTERDLRSRSGHSLGSKSTRQSGVRPFPATWK", "length": 423 }, "evidence": [ { "id": "F1NZA9", "url": "https://omabrowser.org/oma/group/F1NZA9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "O95922-1", "protein_name": "Polyglutamylase complex subunit TTLL1", "gene_name": "TTLL1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAGKVKWVTDIEKSVLINNFEKRGWVQVTENEDWNFYWMSVQTIRNVFSVEAGYRLSDDQIVNHFPNHYELTRKDLMVKNIKRYRKELEKEGSPLAEKDENGKYLYLDFVPVTYMLPADYNLFVEEFRKSPSSTWIMKPCGKAQGKGIFLINKLSQIKKWSRDSKTSSFVSQSNKEAYVISLYINNPLLIGGRKFDLRLYVLVSTYRPLRCYMYKLGFCRFCTVKYTPSTSELDNMFVHLTNVAIQKHGEDYNHIHGGKWTVSNLRLYLESTRGKEVTSKLFDEIHWIIVQSLKAVAPVMNNDKHCFECYGYDIIIDDKLKPWLIEVNASPSLTSSTANDRILKYNLINDTLNIAVPNGEIPDCKWNKSPPKEVLGNYEILYDEELAQGDGADRELRSRQGQSLGPRAGRSRDSGRAVLTTWK", "length": 423 }, "evidence": [ { "id": "F1NZA9", "url": "https://omabrowser.org/oma/group/F1NZA9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q0VC71-1", "protein_name": "Polyglutamylase complex subunit TTLL1", "gene_name": "TTLL1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAGKVKWVTDIEKSVLINNFEKRGWVQVTENEDWNFYWMSVQTIRNVFSVETGYRLSDDQIVNHFPNHYELTRKDLMVKNIKRYRKELEKEGSPLAEKDESGKYLYLDFVPVTYMLPADYNLFVEEFRKSPSSTWIMKPCGKAQGKGIFLINKLSQIKKWSRDSKTSSFVTQSTKEAYVISLYINNPLLIGGRKFDLRLYVLVSTYRPLRCYMYKLGFCRFCTVKYTPSTSELDNMFVHLTNVAIQKHGEDYNHIHGGKWTVNNLRLYLESTRGKEVTSKLFDEIHWIIVQSLKAVAPVMNNDKHCFECYGYDIIIDDKLKPWLIEVNASPSLTSSTANDRILKYNLINDTLNIAVPNGEIPDCKWNKSPPKEVLGNYEILYDEELAQGDGAERELRSRPGQSLGPKGSRLRDAGRTVLTTWK", "length": 423 }, "evidence": [ { "id": "F1NZA9", "url": "https://omabrowser.org/oma/group/F1NZA9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q5PPI9-1", "protein_name": "Polyglutamylase complex subunit TTLL1", "gene_name": "Ttll1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAGRVKWVTDIEKSVLINNFEKRGWVQVTENEDWNFYWMSVQTIRNVFSVETGYRLSDDQIVNHFPNHYELTRKDLMVKNIKRYRKELEKEGSPLAEKDENGKYLYLDFVPVTYMLPADYNLFVEEFRKSPSSTWIMKPCGKAQGKGIFLINKLSQIKKWSRDSKTSSFVSQSTKEAYVISLYINNPLLIGGRKFDLRLYVLVSTYRPLRCYMYKLGFCRFCTVKYTPSTSELDNMFVHLTNVAIQKHGEDYNHIHGGKWTVNNLRLYLESTRGREVTSKLFDEIHWIIVQSLKAVAPVMNNDKHCFECYGYDIIIDDKLKPWLIEVNASPSLTSSTANDRILKYNLINDTLNIAVPNGEIPDCKWNKSPPKEVLGNYEILYDEELAQGDGAERELRSRPGQPVGPRTGRSRDSGRNVLTTWK", "length": 423 }, "evidence": [ { "id": "F1NZA9", "url": "https://omabrowser.org/oma/group/F1NZA9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q91V51-1", "protein_name": "Polyglutamylase complex subunit TTLL1", "gene_name": "Ttll1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAGRVKWVTDIEKSVLINNFEKRGWIQVTENEDWNFYWMSVQTIRNVFSVETGYRLSDDQIVNHFPNHYELTRKDLMVKNIKRYRKELEKEGSPLAEKDENGKYLYLDFVPVTYMLPADYNLFVEEFRKSPSSTWIMKPCGKAQGKGIFLINKLSQIKKWSRDSKTSSFVSQSTKEAYVISVYINNPLLIGGRKFDLRLYVLVSTYRPLRCYMYKLGFCRFCTVKYTPSTSELDNMFVHLTNVAIQKHGEDYNHIHGGKWTVNNLRLYLESTRGREVTSKLFDEIHWIIVQSLKAVAPVMNNDKHCFECYGYDIIIDDKLKPWLIEVNASPSLTSSTANDRILKYNLINDTLNIAVPNGEIPDCKWNKSPPKEVLGNYEILYDEELAQGDGAERELRNRPGQPVGPRAGRSRDSGRSVLTTWK", "length": 423 }, "evidence": [ { "id": "F1NZA9", "url": "https://omabrowser.org/oma/group/F1NZA9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VZ97-1", "protein_name": "Polyglutamylase complex subunit TTLL1", "gene_name": "TTLL1B", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MAVVWDMSQWTQAWRIDSLHPTVRSSGTRTTTSGTIMYGRTSVGANQSVTNGNSNSGANSGGGASGGAQGHDKLKIGFCTDLDKSVLVNNFEKRGWHQVNGDDDWHFYWAGVQTCRNIFSVDSGYRMHDNQMINHFPNHYELSRKDLLVKNIKRYRKDLERDGNPLAEKTESNNSSGTRYLYLDFVPTTFVLPADYNMFVEEYRKFPLSTWIMKPCGKSQGAGIFLINKLSKLKKWSREAKGPFHPQIAKESYVISRYIDNPLLIGGKKFDLRLYVLVASFRPLKAYLFKQGFCRFCTVKYDTSVTELDNMYVHLTNVSVQKHGGEYNTLHGGKWSVQNLALYLEGTRGKEVTDRLFGAISWLIVHSLRAVAPVMASDRHCFECYGYDIIIDNALKPWLVEVNASPSLTSTTVNDRILKYKLIDNILSVVLPPDGVPDVRWNKVPSADALGNFELLIDEELAAQDEQHQNSSSNTHSKTSKMGSRWK", "length": 487 }, "evidence": [ { "id": "F1NZA9", "url": "https://omabrowser.org/oma/group/F1NZA9/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "tubulin-glutamic acid ligase activity", "id": "GO:0070740", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070740", "evidence": [ { "database": "UniProtKB", "id": "F1NZA9", "url": "https://www.uniprot.org/uniprotkb/F1NZA9" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "F1NZA9", "url": "https://www.uniprot.org/uniprotkb/F1NZA9" } ], "pmid": "" }, { "name": "tubulin binding", "id": "GO:0015631", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015631", "evidence": [ { "database": "UniProtKB", "id": "F1NZA9", "url": "https://www.uniprot.org/uniprotkb/F1NZA9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "microtubule", "id": "GO:0005874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005874", "evidence": [ { "database": "UniProtKB", "id": "F1NZA9", "url": "https://www.uniprot.org/uniprotkb/F1NZA9" } ], "pmid": "" }, { "name": "ciliary basal body", "id": "GO:0036064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036064", "evidence": [ { "database": "UniProtKB", "id": "F1NZA9", "url": "https://www.uniprot.org/uniprotkb/F1NZA9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "sperm axoneme assembly", "id": "GO:0007288", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007288", "evidence": [ { "database": "UniProtKB", "id": "F1NZA9", "url": "https://www.uniprot.org/uniprotkb/F1NZA9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 328, "end_pos": 330, "annotation": "n_glycosylation_sequon" }, { "start_pos": 349, "end_pos": 351, "annotation": "n_glycosylation_sequon" }, { "start_pos": 367, "end_pos": 369, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "60148", "name": "", "equation": "(L-glutamyl)(n)-gamma-L-glutamyl-L-glutamyl-[protein] + L-glutamate + ATP = (L-glutamyl)(n+1)-gamma-L-glutamyl-L-glutamyl-[protein] + ADP + phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "60148", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/60148" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1NZA9-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 423, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1NZA9-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1NZA9" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 328, "end_pos": 330 }, { "start_pos": 349, "end_pos": 351 }, { "start_pos": 367, "end_pos": 369 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": 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"publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1NJD8-1", "uniprot_ac": "F1NJD8", "uniprot_id": "F1NJD8_CHICK", "mass": { "chemical_mass": 153234.0, "monoisotopic_mass": 153234.0 }, "refseq": {}, "gene_names": [ { "name": "CEMIP2", "type": "recommended", "evidence": [ { "id": "F1NJD8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NJD8" } ] } ], "protein_names": [ { "name": "hyaluronoglucosaminidase", "type": "recommended", "evidence": [ { "id": "F1NJD8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NJD8/entry#names_and_taxonomy" } ] }, { "name": "3.2.1.35", "type": "synonym", "evidence": [ { "id": "F1NJD8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NJD8/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NJD8", "url": "https://www.uniprot.org/uniprotkb/F1NJD8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CEMIP2", "url": "https://www.uniprot.org/uniprotkb/F1NJD8", "locus": { "chromosome": "Z", "start_pos": 36150157, "end_pos": 36203039, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010014170", "url": "https://www.ensembl.org/id/ENSGALG00010014170" } ] } } ], "crossref": [ { "id": "ENSGALG00000015138", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000015138", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd13938", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13938", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "427250", "url": "https://www.ncbi.nlm.nih.gov/gene/427250", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011050", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011050", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019316", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019316", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039473", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039473", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039477", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039477", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052252", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052252", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055400", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055400", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055401", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055401", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:427250", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427250", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DYGCPRA", "url": "https://omabrowser.org/oma/group/DYGCPRA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YGM5", "url": "https://www.orthodb.org/?gene=A0A8V0YGM5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NJD8", "url": "https://www.orthodb.org/?gene=F1NJD8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15535", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15535", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15535:SF26", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15535:SF26", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10162", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10162", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF15711", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15711", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24605", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24605", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24606", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24606", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YGM5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGM5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YGM5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGM5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NJD8", "url": "https://www.uniprot.org/uniprotkb/F1NJD8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NJD8-1", "url": "https://www.uniprot.org/uniprotkb/F1NJD8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQDTDARGSSPAFLPPQNGSSHRSSGYVPGRIAPLRPPPPSQSHVSAEFTSARQEARAMFASSPPGQHRRHAEANRHKNTLICFAVSSFSLFVALGIFMGIASKYAPDENCPDQNPRLKNWSPGKDPEKKVLIKKGDLFRLNSDATVHSITIQDGGLLVFGDDKDGSKNITLRTRFILIKDGGMLHVGAEKCRYKSKATIILYGKSNEDADVPEFGKKFIGVGPEGTLELHGHQKLSWTLLSKSVNFSGLACGHYAFKKNFSRGLNVRVIDQDTASVLEVLKFDTHEFSEESLKLQNLLKNRSPGRIIAIAVGDSAAKNLLEETRVTIQNLLGSKFVRGLSYRQAWALVGVIGGGNSSCNESVRDYENHSTGGKALAQKEFFTVDGQKFVVRAFSEWNDGVPISGFQVEPVGGVILNLLDDVSSWEPGDRIVVASTDYSMYQTEEFTVLPCPECTKHQVKVKEKPQYPHVGEVIDGVDMRAEVGVLTRNILIKGETENTCYREKECQFFNYDTFGGHIKILKNFTSVHLSYVELKQMGQQQIGSYPVHFHLCGDVDEKGGYSSKTYLDGLSIHHCFSRCVTIHATNGLLIKDTIGYDTLGHCFFIEDGIEQRNTLFHNLGLVTKPGTILPTDRNSTMCTGIRDKVYGSYVPVPATDCMAVSTFWISHPNNHLISNAAAGSQDAGIWYLFHKIATGDSHSLGIETKSELTPLGIFYNNRVHSNFKAGLFIDKGVKTTNASADDPREYLCLDNNARFRPHQDADPEKPRVAALIDGLISFKNNDHGAWVRGGDILIQNSGFADNGIGLTFASDGSFPNDEGASQVVSESLFIGESKNYGFHGGQNKYTGSGGIDNKVRTLPRNRTFPIRGFQIYDGPIHLTKCTFRNFVPTPDRFTSAIGFLMKNPWQMTPRNNISLVKFGPNVSLKAFFGKPGPWFEEVDLDGDKNSIFHDLDGSVTGYKDTYVGRMDNYLIQHPKCINNTEWNGVICSGTYAQVYVQTWNGQNLSMTIVRDEYPSNPMVLKGINQRAVFQQYQPVVMLQKGYTIHWNGKAPNVTYLYLINFNKNDWIRVGLCYQPNTDFTIVLETFQRKSSALSSKVERYTPVSSMLELEKNRSDKKFYFDNSTGLLFLFLQAKYNRDGHSYCSSQGCERIKIVTKDSAKGVSNCMAKAYPKYYQGPAVIKQMPVKTTVPCTKCGTTQMVFTSDPHKNYLLVQINLSGKNELSGSQQAFISVNNTMFSFKDNGILVVVVDACTGTVSGNHLFSGVDIKRVGGYLMSGIPQRSVVLLSTRGKVEIPNNLSDALKCLGTAKPPYLQSNGSVAFLGFRGNFKPSWVKLFTSPSGHELIQIEKYIPLQLEEYGCTRAIKSRRKDLDLLKKATRSH", "length": 1381, "header": "tr|F1NJD8-1|F1NJD8_CHICK Isoform 1 of hyaluronoglucosaminidase OS=Gallus gallus OX=9031 GN=CEMIP2 PE=1 SV=2 CANONICAL=F1NJD8-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YGM5-1", "url": "https://www.uniprot.org/uniprotkb/F1NJD8/entry#A0A8V0YGM5-1", "sequence": { "sequence": "MAYIKSVENCPDQNPRLKNWSPGKDPEKKVLIKKGDLFRLNSDATVHSITIQDGGLLVFGDDKDGSKNITLRTRFILIKDGGMLHVGAEKCRYKSKATIILYGKSNEDADVPEFGKKFIGVGPEGTLELHGHQKLSWTLLSKSVNFSGLACGHYAFKKNFSRGLNVRVIDQDTASVLEVLKFDTHEFSEESLKLQNLLKNRSPGRIIAIAVGDSAAKNLLEETRVTIQNLLGSKFVRGLSYRQAWALVGVIGGGNSSCNESVRDYENHSTGGKALAQKEFFTVDGQKFVVRAFSEWNDGVPISGFQVEPVGGVILNLLDDVSSWEPGDRIVVASTDYSMYQTEEFTVLPCPECTKHQVKVKEKPQYPHVGEVIDGVDMRAEVGVLTRNILIKGETENTCYREKECQFFNYDTFGGHIKILKNFTSVHLSYVELKQMGQQQIGSYPVHFHLCGDVDEKGGYSSKTYLDGLSIHHCFSRCVTIHATNGLLIKDTIGYDTLGHCFFIEDGIEQRNTLFHNLGLVTKPGTILPTDRNSTMCTGIRDKVYGSYVPVPATDCMAVSTFWISHPNNHLISNAAAGSQDAGIWYLFHKIATGDSHSLGIETKSELTPLGIFYNNRVHSNFKAGLFIDKGVKTTNASADDPREYLCLDNNARFRPHQDADPEKPRVAALIDGLISFKNNDHGAWVRGGDILIQNSGFADNGIGLTFASDGSFPNDEGASQVVSESLFIGESKNYGFHGGQNKYTGSGGIDNKVRTLPRNRTFPIRGFQIYDGPIHLTKCTFRNFVPTPDRFTSAIGFLMKNPWQMTPRNNISLVKFGPNVSLKAFFGKPGPWFEEVDLDGDKNSIFHDLDGSVTGYKDTYVGRMDNYLIQHPKCINNTEWNGVICSGTYAQVYVQTWNGQNLSMTIVRDEYPSNPMVLKGINQRAVFQQYQPVVMLQKGYTIHWNGKAPNVTYLYLINFNKNDWIRVGLCYQPNTDFTIVLETFQRKSSALSSKVERYTPVSSMLELEKNRSDKKFYFDNSTGLLFLFLQAKYNRDGHSYCSSQGCERIKIVTKDSAKGVSNCMAKAYPKYYQGPAVIKQMPVKTTVPCTKCGTTQMVFTSDPHKNYLLVQINLSGKNELSGSQQAFISVNNTMFSFKDNGILVVVVDACTGTVSGNHLFSGVDIKRVGGYLMSGIPQRSVVLLSTRGKVEIPNNLSDALKCLGTAKPPYLQSNGSVAFLGFRGNFKPSWVKLFTSPSGHELIQIEKYIPLQLEEYGCTRAIKSRRKDLDLLKKATRSH", "length": 1280, "header": "tr|A0A8V0YGM5-1|A0A8V0YGM5_CHICK Computationally mapped isoform of hyaluronoglucosaminidase OS=Gallus gallus OX=9031 GN=CEMIP2 PE=1 SV=1 CANONICAL=F1NJD8-1" }, "locus": { "chromosome": "Z", "start_pos": 36179649, "end_pos": 36152174, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034064.1", "url": "https://www.ensembl.org/id/ENSGALT00010034064.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020019.1", "url": "https://www.ensembl.org/id/ENSGALP00010020019.1" } ] } }, { "isoform_ac": "F1NJD8-1", "url": "https://www.uniprot.org/uniprotkb/F1NJD8/entry#F1NJD8-1", "sequence": { "sequence": "MQDTDARGSSPAFLPPQNGSSHRSSGYVPGRIAPLRPPPPSQSHVSAEFTSARQEARAMFASSPPGQHRRHAEANRHKNTLICFAVSSFSLFVALGIFMGIASKYAPDENCPDQNPRLKNWSPGKDPEKKVLIKKGDLFRLNSDATVHSITIQDGGLLVFGDDKDGSKNITLRTRFILIKDGGMLHVGAEKCRYKSKATIILYGKSNEDADVPEFGKKFIGVGPEGTLELHGHQKLSWTLLSKSVNFSGLACGHYAFKKNFSRGLNVRVIDQDTASVLEVLKFDTHEFSEESLKLQNLLKNRSPGRIIAIAVGDSAAKNLLEETRVTIQNLLGSKFVRGLSYRQAWALVGVIGGGNSSCNESVRDYENHSTGGKALAQKEFFTVDGQKFVVRAFSEWNDGVPISGFQVEPVGGVILNLLDDVSSWEPGDRIVVASTDYSMYQTEEFTVLPCPECTKHQVKVKEKPQYPHVGEVIDGVDMRAEVGVLTRNILIKGETENTCYREKECQFFNYDTFGGHIKILKNFTSVHLSYVELKQMGQQQIGSYPVHFHLCGDVDEKGGYSSKTYLDGLSIHHCFSRCVTIHATNGLLIKDTIGYDTLGHCFFIEDGIEQRNTLFHNLGLVTKPGTILPTDRNSTMCTGIRDKVYGSYVPVPATDCMAVSTFWISHPNNHLISNAAAGSQDAGIWYLFHKIATGDSHSLGIETKSELTPLGIFYNNRVHSNFKAGLFIDKGVKTTNASADDPREYLCLDNNARFRPHQDADPEKPRVAALIDGLISFKNNDHGAWVRGGDILIQNSGFADNGIGLTFASDGSFPNDEGASQVVSESLFIGESKNYGFHGGQNKYTGSGGIDNKVRTLPRNRTFPIRGFQIYDGPIHLTKCTFRNFVPTPDRFTSAIGFLMKNPWQMTPRNNISLVKFGPNVSLKAFFGKPGPWFEEVDLDGDKNSIFHDLDGSVTGYKDTYVGRMDNYLIQHPKCINNTEWNGVICSGTYAQVYVQTWNGQNLSMTIVRDEYPSNPMVLKGINQRAVFQQYQPVVMLQKGYTIHWNGKAPNVTYLYLINFNKNDWIRVGLCYQPNTDFTIVLETFQRKSSALSSKVERYTPVSSMLELEKNRSDKKFYFDNSTGLLFLFLQAKYNRDGHSYCSSQGCERIKIVTKDSAKGVSNCMAKAYPKYYQGPAVIKQMPVKTTVPCTKCGTTQMVFTSDPHKNYLLVQINLSGKNELSGSQQAFISVNNTMFSFKDNGILVVVVDACTGTVSGNHLFSGVDIKRVGGYLMSGIPQRSVVLLSTRGKVEIPNNLSDALKCLGTAKPPYLQSNGSVAFLGFRGNFKPSWVKLFTSPSGHELIQIEKYIPLQLEEYGCTRAIKSRRKDLDLLKKATRSH", "length": 1381, "header": "tr|F1NJD8-1|F1NJD8_CHICK Isoform 1 of hyaluronoglucosaminidase OS=Gallus gallus OX=9031 GN=CEMIP2 PE=1 SV=2 CANONICAL=F1NJD8-1" }, "locus": { "chromosome": "Z", "start_pos": 36183471, "end_pos": 36152174, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034067.1", "url": "https://www.ensembl.org/id/ENSGALT00010034067.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020022.1", "url": "https://www.ensembl.org/id/ENSGALP00010020022.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "gga:427250", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427250", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2JZA7-1", "protein_name": "hyaluronoglucosaminidase", "gene_name": "Cemip2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MYAAGSRGHSPAFLQPQNGNGHRSPGYVPGKVVPFRPAPPPKNHASAKLTSRSQEAPATFAFSPEEQRTPREDRKQKRHKNTFICFAITSFSFFVTLAVILGISSKYAPDENCPDQNPRLRNWDPGQDSAKHIVIKEGDMLRLTSDATVNSIVIQDGGLLVFGDDKDGSRNITLRTRYILIQDGGALHIGAEKCRYRSKATITLYGKSDEHESMPTFGKKFIGVEAGGTLELHGARRTSWTMLARTLHSSGLPFGSYAFEKDFSRGLNVRVIDQDTARVLEHEKFDTHEYHNESRRLQEFLRAQDPGRIVAIAVGDSAVKSLLQGTIQMIQDRLGSKLIQGLGYRQAWALVGVIDGGSSSCNESVRNYENHSTGGKALAQGEFYTLDGQKFSVTAYSEWIEGISLSGFRVDIADGVKLHLLDDVSSWGAGDRIVVASTDYSMYQAEELTLLPCPECSRFQVKVKEIPQYLHVGEIIDGIDMRAEVGLLTRNIVIQGETEDSCYADNHCQFFDYDTFGGHVMIEKNFTSVHLSYVELKHMGQQHLGRYPVHFHLCGDVDSKGGYRVPTSVNGLSIHHSFSRCITVHGSSGLLIKDTIGFDTLGHCFFLEDGVEQRNILFHNLGLLTKPGTLLPTDRNSSMCTVMRDGVFGNYIPVPTTDCMAVSTFWIAHPNNHLINNAAAGSQDAGIWYLFHKEPTGESSGMQLLEKPELTPLGIFYNNRVHSNFKAGLFVDKGVKTTNSSASDPREYLCLDNSARFRPHQDADPEKPRVAAVIDRLIAFKNNDNGAWVRGGDIIVQNSAFADNGKGLTFASDGSFPSDEGSSQEVSESLFVGESKNYGSQGGQNKYMGTGGIDQKPRTLPRNRTFPIRGFQIYDGPIHLTKSTFKKYVPTPDRYSSAIGFLMKNSWQTTPRNNVSLVKFGPQVSLNVFFGKPGPWFEDCELDGDKNSIFHDIDGSVTGYKDTYVGRMDNYLIRHPNCVSVTKWNAVVCSGTYAQVYVQTWNTPNLSMIITRDEYPSHPMVLRGINQRAISPQYQPVVMLEKGYTIHWSGPAPRTTFLYLVNFNKDDWIRVGLCYPSNTSFQVTVGFLQRQNGSLSRIEEYEPAQSMEELQKKPSERKFYFDSGTGLLFLYLRAHSHRDGHSYCSSQGCERVKIQAATDSKDMSNCMAKAYPQYYKKPSAVKRMPAMLTGFCQGCGTHQMVFSSDPHKSYLPVRFQSPGKAEIQRGEPSVISVNGTDFTFRSAGAFLLIVDACSVPFRLTEKRMFLSADISHLEEYLKASIPPRSIVLLSTRGEIKQMNISDSFVLLGLAKPAHLYNKGSTVFLGFSGNFTPSWTRLFTSPDVQGLGVLEQYLPLQMEEYGCSRTSSVHRRDLELLQQALKGL", "length": 1383 }, "evidence": [ { "id": "F1NJD8", "url": "https://omabrowser.org/oma/group/F1NJD8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1MNY2-1", "protein_name": "hyaluronoglucosaminidase", "gene_name": "CEMIP2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MHATNSRGHSPAFLQPQNGNSHHSSGYVPGKVVPLRPPPPPKSQASAKFTSIRQEAQASFGFSSEEQQVQRERRKQKRHKNTFICFAITSFSFFVALAVILGISSKYAPDENCPDQNPRLRNWDPGQDSAKQVVIKEGDMFRLTSDATVNSIVIQDGGLLVFGDDKDGSRNITLRTHYILIKDGGALHIGAEKCRYKSKATIALYGKSDEGESMPTFGKKFIGVEAGGTLELHGTQKASWTLLVRTLNSSGLTFGSYAFKKDFSRGLNVRVIDQDTAKILEIERFDTHEFQNESRRLQKFLRDQDPGRIVAIAVGDSAVKSLLQGTIQMIQDRLGSKLIQGLGYRQAWALVGVIDGGSTSCNESVRNYENHSSGGKALAQREFYTVDGQKFSVTAYSEWKEGISFSGFWVEAIDGVKLHLLDDVSSWEPGDQIVVASTDYSMYQAEEFTLLPCPECSRFQVKVKETPQFLHMGEIIDGVDMRAEVGILTQNIVIRGEMEDSCYAENQCQFFDYDTFGGHVMIKKNFTSVHLSHVELKHMGQQHLGRYPVHFHLCGDVDYKGGYRHATFVDGLSIHHSFSRCITVHGTNGLLIKDTVGFDTLGHCFFLEDGIEQRNTLFHNLGLLTKPGTLLPTDRNNSMCITMREKVFGNYIPVPATDCMAVSTFWIAHPNNNLINNAAAGSQDAGIWYLFHKEPTGESSGLQLLAKPELTPLGIFYNNRVHSSFKAGLFIDKGVKTTNASAADPREYLCLDNSARFRPHQDGDPEKPRVAALIDRLIAFKNNDNGAWVRGGDIVVQNSAFADNGIGLTFASDGSFPSDEGSSQEVSESLFVGESRNYGFQGGQNKYVGTGGIDLKPRTLPRNRTFPIRGFQIYDGPIHLTRCTFQKYVPTLDRYTSAIGFLMKNSWQITPRNNISFVKFGPHVSLNVFFGKPGPWFEDCELDGDKNSIFHDIDGSVTGYKDAYVGRMDNYLIRHPSCINVTKWNAVVCSGSYAQVYVQTWSTPNLTMTITRDEYPDYPMVLRGINQKAAFSQYQPVIMLEKGYTIHWNGPAPKIAFLYLINFNKNDWIRVGLCYPSNTSFQVTFGFLQRHNGSLSKMEEYEPVHSLEELQKKQSERKFYFDSSTGLLFLYLKAKSHRDGHSYCSSQGCERVKIQAATDSKDISNCMAKAYPRYYRKPSALKSMPSMLKGLCQGCGTRQVVFTSDPHISYLPVQFRSPSQAEIQRGDASVISINGTDFPLRSVGVLLLIVDACSVPFRLTEKKIFSFTDVSRMEEYLKTSIPPRSVVLLSTRGQIKQFNISDSLVPLGLAKPANLYNKGSTIFLGFNGNFKPSWTKLYTSPARQGLGLLEQFIPLQLDEYGCHRADTIRRRDLELLKQTSKAH", "length": 1383 }, "evidence": [ { "id": "F1NJD8", "url": "https://omabrowser.org/oma/group/F1NJD8/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q54KF6-1", "protein_name": "Protein DDB_G0287365", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MMSFNLILILIIFLILIQNYVIDGNDNFNLIKCPDEIPNLKKWSNYKSWKKLKLPIKGESINITTPILMDIKPPDLDVIRIFDKGMLVWKHINNLELRVKAILIYDGGQLIIGSEQCKFKYKATITLIGDSIYTEINQTINGNEYGQKVIGIDNGGTIELHSEVTKTTWTKLISTISPSTFNSNKNILTLLDNVNDWPIGSEILITSTDYDMEQSETNFIVKCSTCKTNQIKLKNPIKYLHWGSITKGVDERAEVALLTRNIKIQGQVGKTCVNNKLVCDFFPFDSFGAHIMIRKGFVNAHFFGIELFNVGQSHVVSRYPIHFHLCDRVDELGGYENPAYIKHCSVHKSFSRCYVVHSTDGLLIHDNIGFDSIGHCYMLCDGIEMDNVFSHNLGAVTRYGLLFPHDRSCDMCSRIQPNDFNGNPTQCTECNAVSTFWISNPWNTLIDNVASGSDSTGIWYLFSDYPSGLSHERGIKYNIKPYLIPVKKFYNNNVHSCTNGIQIDGGVKLTPPSKTQPQQLNSMINARYKPRSNPKNPNSKPSPSIFNGATIYKNKWRGCWARGGFLFMKNFKIADNAIGFTFASEGTIPGDQNVGQYIYKSLIVGESDNIGQQSNNIPIVNGRTNPYGENGLMPIRGFEIYDGTISLDSMVFSEFKSLPPLFRNSSAIGFLRFNDWQSSSETTIKNIKYINVDKEIHFEQSLMDGDKISTLRDLDGSTTKLSNSILVRNLLFYSTNNCYYKKPWDALICKEDTRQIYICNDDTNSTNYLSLSSSVVAIRDNIENQKIEQIGLPNHSPRNRFQFLVFKNHHYDFHFPNHPTPPILRVQPMNWKQSEKFTFGICIGISKGINLKVLKTVNGTYGNSNFVEELYPTFSMNLISESTYYFNEITSMLYIMYYQYNSKDHLNYCPEYGCEELVIKISGKNSGRVTGDCQSLAYGSSFTLFDEVVNRKFENSFQMDKSIIHNSEYAYRGNAYLPYHPTSKSQIQFKCNHCIPSVGIKYFEIWVNGNRNSNQRISIQLFYSINSNQLKSQPFAIDKNYFKKNSWVLVRILFENLKNLLPENHIHLISSFDGLSIINSLELNQPSLFLDNIKFIYDN", "length": 1099 }, "evidence": [ { "id": "F1NJD8", "url": "https://omabrowser.org/oma/group/F1NJD8/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q5FWI3-1", "protein_name": "Cell surface hyaluronidase", "gene_name": "Cemip2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MYAAGSRGHSPAFLQPQNGNGHRSPGYVPGKVVPLRPAPPPKNHASAKLTSRSQDAPATFAFSPEEQRTPSESRKRKRHKNTFICFAITSFSFFVALAVILGISSKYAPDENCPDQNPRLRNWDPGQDSAKHIVIKEGDLFRLTSDATVDSIVIQDGGLLVFGDDKDGSKNITLRTRYILIQDGGALHIGAEKCRYRSKATITLYGKSDERESMPIFGKKFIGVEAGGTLELHGAQRTSWTMLARTLHSSGLPFGSYAFEKDFSRGLNVRVIDQDTARVLENEKFDTHEYHNESRRLQEFLRAQEPGRIVAIAVGDSAVKSLLQGTIQMIQDRLGSKLIQGLGYRQAWALVGVIDGGSSSCNESVRNYENHSTGGKALAQGEFYTLDGQKFSVTAYSEWSQGISLSGFRVDIADGVKLHLLDDVSTWEAGDRIVVASTDYSMYQAEELTLLRCPECSRSQVKVKEIPQYLHVGEIIDGIDMRAEVGLLTRNIVIQGEMEDSCYAENHCQFFDYDTFGGHVMIEKNFTSVHLSYVELKHMGQQHMGRYPVHFHLCGDVDSKGGYSQPASVDGLSVHHSFSRCITVHGTSGLLIKDTIGFDTLGHCFFLEDGVEQRNILYHNLGLLTKPGTLLPTDRNSSMCTVMRDGVFGNYVPVPTTDCMAVSTFWIAHPNNHLINNAAAGSQDAGIWYLFHKEPTGESSGLQLLEKPELTPLGIFYNNRVHSNFKAGLFVDKGVKTTNASASDPREYLCLDNSARFRPHQDADPEKPRVAAIIDRLIAFKNNDNGAWVRGGDIIVQNSAFADNGKGLTFASDGSFPSDEGSSQEVTESLFVGESRNYGFQGGQNKYMGTGGIDQKPRTLPRNRTFPIRGFQIYDGPIHLTKSTFKKYVPTPDRYSSAIGFLMKNSWQTTPRNNVSLVKFGPQVSLNVFFGKPGPWFEDCELDGDKNSIFHDIDGSVTGYKDTYVGRMDNYLIRHPNCVNVTKWNAVICSGTYAQVYVQTWNTPNLSMIITRDEYPSHPMVLRGINQRAISPQYQPVVMLEKGYTIHWNGPAPRTTFLYLVNFNKDDWIRVGLCYPANTSFQVTVGFLQRQNGSLSRIEDYEPARSMEELQKKPSERKFYFDSGTGLLFLYLRAHSHRDGHSYCSSQGCERVKIQAATDSKDISNCMAKAYPQYYKKPSAVKRMPAMLTGLCQGCGTHQMVFTSDPHKSYLPVRFQSPGKAEIQRGDPSIISVNGTDFTFRSAGALLLIVDACSVPFRVKEKRMFLSADVSHMEEYFKASIPPRSIVLLSTRGEIKQLNISDSLAVLGLAKPAHLYSKGSVVFLGFSGNFAPSWTKLFTSPDEQGLGVLEQFLPLQMEEYGCSRTGSVHRRDLDLLQQALKVL", "length": 1383 }, "evidence": [ { "id": "F1NJD8", "url": "https://omabrowser.org/oma/group/F1NJD8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9UHN6-1", "protein_name": "Cell surface hyaluronidase CEMIP2", "gene_name": "CEMIP2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MYATDSRGHSPAFLQPQNGNSRHPSGYVPGKVVPLRPPPPPKSQASAKFTSIRREDRATFAFSPEEQQAQRESQKQKRHKNTFICFAITSFSFFIALAIILGISSKYAPDENCPDQNPRLRNWDPGQDSAKQVVIKEGDMLRLTSDATVHSIVIQDGGLLVFGDNKDGSRNITLRTHYILIQDGGALHIGAEKCRYKSKATITLYGKSDEGESMPTFGKKFIGVEAGGTLELHGARKASWTLLARTLNSSGLPFGSYTFEKDFSRGLNVRVIDQDTAKILESERFDTHEYRNESRRLQEFLRFQDPGRIVAIAVGDSAAKSLLQGTIQMIQERLGSELIQGLGYRQAWALVGVIDGGSTSCNESVRNYENHSSGGKALAQREFYTVDGQKFSVTAYSEWIEGVSLSGFRVEVVDGVKLNLLDDVSSWKPGDQIVVASTDYSMYQAEEFTLLPCSECSHFQVKVKETPQFLHMGEIIDGVDMRAEVGILTRNIVIQGEVEDSCYAENQCQFFDYDTFGGHIMIMKNFTSVHLSYVELKHMGQQQMGRYPVHFHLCGDVDYKGGYRHATFVDGLSIHHSFSRCITVHGTNGLLIKDTIGFDTLGHCFFLEDGIEQRNTLFHNLGLLTKPGTLLPTDRNNSMCTTMRDKVFGNYIPVPATDCMAVSTFWIAHPNNNLINNAAAGSQDAGIWYLFHKEPTGESSGLQLLAKPELTPLGIFYNNRVHSNFKAGLFIDKGVKTTNSSAADPREYLCLDNSARFRPHQDANPEKPRVAALIDRLIAFKNNDNGAWVRGGDIIVQNSAFADNGIGLTFASDGSFPSDEGSSQEVSESLFVGESRNYGFQGGQNKYVGTGGIDQKPRTLPRNRTFPIRGFQIYDGPIHLTRSTFKKYVPTPDRYSSAIGFLMKNSWQITPRNNISLVKFGPHVSLNVFFGKPGPWFEDCEMDGDKNSIFHDIDGSVTGYKDAYVGRMDNYLIRHPSCVNVSKWNAVICSGTYAQVYVQTWSTQNLSMTITRDEYPSNPMVLRGINQKAAFPQYQPVVMLEKGYTIHWNGPAPRTTFLYLVNFNKNDWIRVGLCYPSNTSFQVTFGYLQRQNGSLSKIEEYEPVHSLEELQRKQSERKFYFDSSTGLLFLYLKAKSHRHGHSYCSSQGCERVKIQAATDSKDISNCMAKAYPQYYRKPSVVKRMPAMLTGLCQGCGTRQVVFTSDPHKSYLPVQFQSPDKAETQRGDPSVISVNGTDFTFRSAGVLLLVVDPCSVPFRLTEKTVFPLADVSRIEEYLKTGIPPRSIVLLSTRGEIKQLNISHLLVPLGLAKPAHLYDKGSTIFLGFSGNFKPSWTKLFTSPAGQGLGVLEQFIPLQLDEYGCPRATTVRRRDLELLKQASKAH", "length": 1383 }, "evidence": [ { "id": "F1NJD8", "url": "https://omabrowser.org/oma/group/F1NJD8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F1NJD8", "url": "https://www.uniprot.org/uniprotkb/F1NJD8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "carbohydrate binding", "id": "GO:0030246", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030246", "evidence": [ { "database": "UniProtKB", "id": "F1NJD8", "url": "https://www.uniprot.org/uniprotkb/F1NJD8" } ], "pmid": "" }, { "name": "hyalurononglucosaminidase activity", "id": "GO:0004415", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004415", "evidence": [ { "database": "UniProtKB", "id": "F1NJD8", "url": "https://www.uniprot.org/uniprotkb/F1NJD8" } ], "pmid": "" }, { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "F1NJD8", "url": "https://www.uniprot.org/uniprotkb/F1NJD8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "hyaluronan catabolic process", "id": "GO:0030214", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030214", "evidence": [ { "database": "UniProtKB", "id": "F1NJD8", "url": "https://www.uniprot.org/uniprotkb/F1NJD8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1003, "end_pos": 1005, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1052, "end_pos": 1054, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1112, "end_pos": 1114, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1122, "end_pos": 1124, "annotation": "n_glycosylation_sequon" }, { "start_pos": 120, "end_pos": 122, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1215, "end_pos": 1217, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1233, "end_pos": 1235, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1297, "end_pos": 1299, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1316, "end_pos": 1318, "annotation": "n_glycosylation_sequon" }, { "start_pos": 169, "end_pos": 171, "annotation": "n_glycosylation_sequon" }, { "start_pos": 18, "end_pos": 20, "annotation": "n_glycosylation_sequon" }, { "start_pos": 246, "end_pos": 248, "annotation": "n_glycosylation_sequon" }, { "start_pos": 260, "end_pos": 262, "annotation": "n_glycosylation_sequon" }, { "start_pos": 301, "end_pos": 303, "annotation": "n_glycosylation_sequon" }, { "start_pos": 356, "end_pos": 358, "annotation": "n_glycosylation_sequon" }, { "start_pos": 360, "end_pos": 362, "annotation": "n_glycosylation_sequon" }, { "start_pos": 368, "end_pos": 370, "annotation": "n_glycosylation_sequon" }, { "start_pos": 523, "end_pos": 525, "annotation": "n_glycosylation_sequon" }, { "start_pos": 634, "end_pos": 636, "annotation": "n_glycosylation_sequon" }, { "start_pos": 737, "end_pos": 739, "annotation": "n_glycosylation_sequon" }, { "start_pos": 861, "end_pos": 863, "annotation": "n_glycosylation_sequon" }, { "start_pos": 912, "end_pos": 914, "annotation": "n_glycosylation_sequon" }, { "start_pos": 921, "end_pos": 923, "annotation": "n_glycosylation_sequon" }, { "start_pos": 978, "end_pos": 980, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1NJD8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NJD8" }, { "id": "PS51484", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51484" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G8", "eco_id": "ECO_0000259", "start_pos": 119, "end_pos": 243, "start_aa": "Lys", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "3.2.1.35", "ec_name": "Random hydrolysis of (1->4)-linkages between N-acetyl-beta-D-glucosamine and D-glucuronate residues in hyaluronate.", "evidence": [ { "id": "3.2.1.35", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=3.2.1.35" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1003, "end_pos": 1005 }, { "start_pos": 1052, "end_pos": 1054 }, { "start_pos": 1112, "end_pos": 1114 }, { "start_pos": 1122, "end_pos": 1124 }, { "start_pos": 120, "end_pos": 122 }, { "start_pos": 1215, "end_pos": 1217 }, { "start_pos": 1233, "end_pos": 1235 }, { "start_pos": 1297, "end_pos": 1299 }, { "start_pos": 1316, "end_pos": 1318 }, { "start_pos": 169, "end_pos": 171 }, { "start_pos": 18, "end_pos": 20 }, { "start_pos": 246, "end_pos": 248 }, { "start_pos": 260, "end_pos": 262 }, { "start_pos": 301, "end_pos": 303 }, { "start_pos": 356, "end_pos": 358 }, { "start_pos": 360, "end_pos": 362 }, { "start_pos": 368, "end_pos": 370 }, { "start_pos": 523, "end_pos": 525 }, { "start_pos": 634, "end_pos": 636 }, { "start_pos": 737, "end_pos": 739 }, { "start_pos": 861, "end_pos": 863 }, { "start_pos": 912, "end_pos": 914 }, { "start_pos": 921, "end_pos": 923 }, { "start_pos": 978, "end_pos": 980 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1P011-1", "uniprot_ac": "F1P011", "uniprot_id": "F1P011_CHICK", "mass": { "chemical_mass": 54077.0, "monoisotopic_mass": 54077.0 }, "refseq": { "ac": "XP_040502746", "name": "calcium/calmodulin-dependent protein kinase type II subunit alpha isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040502746" }, "gene_names": [ { "name": "CAMK2A", "type": "recommended", "evidence": [ { "id": "F1P011", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P011" } ] }, { "name": "CAMK2A", "type": "synonym", "evidence": [ { "id": "XP_040502746", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040502746" } ] } ], "protein_names": [ { "name": "calcium/calmodulin-dependent protein kinase", "type": "recommended", "evidence": [ { "id": "F1P011", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P011/entry#names_and_taxonomy" } ] }, { "name": "2.7.11.17", "type": "synonym", "evidence": [ { "id": "F1P011", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P011/entry#names_and_taxonomy" } ] }, { "name": "calcium/calmodulin-dependent protein kinase type II subunit alpha isoform X2", "type": "synonym", "evidence": [ { "id": "XP_040502746", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040502746" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052544.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040502746", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040502746" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1P011", "url": "https://www.uniprot.org/uniprotkb/F1P011" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CAMK2A", "url": "https://www.uniprot.org/uniprotkb/F1P011", "locus": { "chromosome": "13", "start_pos": 12818019, "end_pos": 12795785, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013576", "url": "https://www.ensembl.org/id/ENSGALG00010013576" } ] } } ], "crossref": [ { "id": "F1P011", "url": "https://alphafold.ebi.ac.uk/entry/F1P011", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000005621", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000005621", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd14086", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14086", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "374175", "url": "https://www.ncbi.nlm.nih.gov/gene/374175", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000719", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000719", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008271", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008271", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011009", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011009", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013543", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013543", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017441", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017441", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032710", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032710", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:374175", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:374175", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YFENCEF", "url": "https://omabrowser.org/oma/group/YFENCEF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YKM7", "url": "https://www.orthodb.org/?gene=A0A8V0YKM7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YKQ0", "url": "https://www.orthodb.org/?gene=A0A8V0YKQ0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YL82", "url": "https://www.orthodb.org/?gene=A0A8V0YL82", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YT27", "url": "https://www.orthodb.org/?gene=A0A8V0YT27", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YT86", "url": "https://www.orthodb.org/?gene=A0A8V0YT86", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NGS8", "url": "https://www.orthodb.org/?gene=F1NGS8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1P011", "url": "https://www.orthodb.org/?gene=F1P011", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24347", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24347", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00069", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00069", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08332", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08332", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-3371571", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3371571", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-4086398", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-4086398", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-438066", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-438066", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-5673001", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5673001", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-877300", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-877300", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_040502746", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040502746", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "17989", "url": "https://www.rhea-db.org/rhea/17989", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "46608", "url": "https://www.rhea-db.org/rhea/46608", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YKM7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKM7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YKM7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKM7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YKQ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKQ0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YKQ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKQ0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YL82", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL82", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YL82-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL82-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YT27", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YT27", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YT27-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YT27-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YT86", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YT86", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YT86-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YT86-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NGS8", "url": "https://www.uniprot.org/uniprotkb/F1NGS8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NGS8-1", "url": "https://www.uniprot.org/uniprotkb/F1NGS8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1P011", "url": "https://www.uniprot.org/uniprotkb/F1P011", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1P011-1", "url": "https://www.uniprot.org/uniprotkb/F1P011-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MATITCNRFTEEYQLFEELGKGAFSIVRRCVKVLAGQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGDQQAWFGFAGTPGYLSPEVLRKDPYGKAVDLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPSKRITAAEALKHPWISHRATVASCMHRQETVDCLKKFNARRKLKGAILTTMLATRNFSGGKSGGNKKNDGVKESSESTNTTIEDEDTKVRKQEIIKVTEQLIEAISNGDFESYTKMCDPGMTAFEPEALGNLVEGLDFHRFYFENLWSRNSKPVHTTILNPHIHLMGDESACIAYIRITQYVDAGGIPRTAQSEETRIWHRRDGKWQIVHFHRSGAPSVLPQ", "length": 478, "header": "tr|F1P011-1|F1P011_CHICK Isoform 1 of calcium/calmodulin-dependent protein kinase OS=Gallus gallus OX=9031 GN=CAMK2A PE=3 SV=5 CANONICAL=F1P011-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YKM7-1", "url": "https://www.uniprot.org/uniprotkb/F1P011/entry#A0A8V0YKM7-1", "sequence": { "sequence": "MGAPGCGVPGATWGSGAWPAVGGGKSGGNKKNDGVKKRKSSSSVQLMESSESTNTTIEDEDTKVRKQEIIKVTEQLIEAISNGDFESYTKMCDPGMTAFEPEALGNLVEGLDFHRFYFENLWSRNSKPVHTTILNPHIHLMGDESACIAYIRITQYVDAGGIPRTAQSEETRIWHRRDGKWQIVHFHRSGAPSVLPQ", "length": 197, "header": "tr|A0A8V0YKM7-1|A0A8V0YKM7_CHICK Computationally mapped isoform of Calcium/calmodulin dependent protein kinase II alpha OS=Gallus gallus OX=9031 GN=CAMK2A PE=4 SV=1 CANONICAL=F1P011-1" }, "locus": { "chromosome": "13", "start_pos": 12815653, "end_pos": 12808544, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032677.1", "url": "https://www.ensembl.org/id/ENSGALT00010032677.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019365.1", "url": "https://www.ensembl.org/id/ENSGALP00010019365.1" } ] } }, { "isoform_ac": "A0A8V0YKQ0-1", "url": "https://www.uniprot.org/uniprotkb/F1P011/entry#A0A8V0YKQ0-1", "sequence": { "sequence": "IAGSANCCSDCEVLAGQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIGKRTLRRCLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGDQQAWFGFAGTPGYLSPEVLRKDPYGKAVDLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPSKRITAAEALKHPWISHRATVASCMHRQETVDCLKKFNARRKLKLLLAWGEDWAHRAVSSLFFAQESSESTNTTIEDEDTKVRKQEIIKVTEQLIEAISNGDFESYTKMCDPGMTAFEPEALGNLVEGLDFHRFYFENLWSRNSKPVHTTILNPHIHLMGDESACIAYIRITQYVDAGGIPRTAQSEETRIWHRRDGKWQIVHFHRSGAPSVLPQ", "length": 441, "header": "tr|A0A8V0YKQ0-1|A0A8V0YKQ0_CHICK Computationally mapped isoform of calcium/calmodulin-dependent protein kinase OS=Gallus gallus OX=9031 GN=CAMK2A PE=3 SV=1 CANONICAL=F1P011-1" }, "locus": { "chromosome": "13", "start_pos": 12815653, "end_pos": 12799765, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032719.1", "url": "https://www.ensembl.org/id/ENSGALT00010032719.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019385.1", "url": "https://www.ensembl.org/id/ENSGALP00010019385.1" } ] } }, { "isoform_ac": "A0A8V0YL82-1", "url": "https://www.uniprot.org/uniprotkb/F1P011/entry#A0A8V0YL82-1", "sequence": { "sequence": "MFPWHTAGGARPALLRSSCGGGRVGPAGVFLGCRPVAQLSAVGSDSGGCWTHELLLAWGEDWAHRAVSSLFFAQESSESTNTTIEDEDTKVRKQEIIKVTEQLIEAISNGDFESYTKMCDPGMTAFEPEALGNLVEGLDFHRFYFENLWSRNSKPVHTTILNPHIHLMGDESACIAYIRITQYVDAGGIPRTAQSEETRIWHRRDGKWQIVHFHRSGAPSVLPQ", "length": 224, "header": "tr|A0A8V0YL82-1|A0A8V0YL82_CHICK Computationally mapped isoform of Calcium/calmodulin dependent protein kinase II alpha OS=Gallus gallus OX=9031 GN=CAMK2A PE=4 SV=1 CANONICAL=F1P011-1" }, "locus": { "chromosome": "13", "start_pos": 12815653, "end_pos": 12813170, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032655.1", "url": "https://www.ensembl.org/id/ENSGALT00010032655.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019352.1", "url": "https://www.ensembl.org/id/ENSGALP00010019352.1" } ] } }, { "isoform_ac": "A0A8V0YT27-1", "url": "https://www.uniprot.org/uniprotkb/F1P011/entry#A0A8V0YT27-1", "sequence": { "sequence": "MGILECFAETPQEPGGKSGGNKKNDGVKKRKSSSSVQLMESSESTNTTIEDEDTKVRKQEIIKVTEQLIEAISNGDFESYTKMCDPGMTAFEPEALGNLVEGLDFHRFYFENLWSRNSKPVHTTILNPHIHLMGDESACIAYIRITQYVDAGGIPRTAQSEETRIWHRRDGKWQIVHFHRSGAPSVLPQ", "length": 189, "header": "tr|A0A8V0YT27-1|A0A8V0YT27_CHICK Computationally mapped isoform of Calcium/calmodulin dependent protein kinase II alpha OS=Gallus gallus OX=9031 GN=CAMK2A PE=4 SV=1 CANONICAL=F1P011-1" }, "locus": { "chromosome": "13", "start_pos": 12815653, "end_pos": 12808189, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032672.1", "url": "https://www.ensembl.org/id/ENSGALT00010032672.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019362.1", "url": "https://www.ensembl.org/id/ENSGALP00010019362.1" } ] } }, { "isoform_ac": "A0A8V0YT86-1", "url": "https://www.uniprot.org/uniprotkb/F1P011/entry#A0A8V0YT86-1", "sequence": { "sequence": "MATITCNRFTEEYQLFEELGKGAFSIVRRCVKVLAGQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHDSISEEGHHYLIFDLHCIQQILEAVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGDQQAWFGFAGTPGYLSPEVLRKDPYGKAVDLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPSKRITAAEALKHPWISHRATVASCMHRQETVDCLKKFNARRKLKVICTPSSPCWCRMLGGGCGGWELKDWAHRAVSSLFFAQESSESTNTTIEDEDTKVRKQEIIKVTEQLIEAISNGDFESYTKMCDPGMTAFEPEALGNLVEGLDFHRFYFENLWSRNSKPVHTTILNPHIHLMGDESACIAYIRITQYVDAGGIPRTAQSEETRIWHRRDGKWQIVHFHRSGAPSVLPQ", "length": 466, "header": "tr|A0A8V0YT86-1|A0A8V0YT86_CHICK Computationally mapped isoform of calcium/calmodulin-dependent protein kinase OS=Gallus gallus OX=9031 GN=CAMK2A PE=3 SV=1 CANONICAL=F1P011-1" }, "locus": { "chromosome": "13", "start_pos": 12815653, "end_pos": 12795871, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032795.1", "url": "https://www.ensembl.org/id/ENSGALT00010032795.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019427.1", "url": "https://www.ensembl.org/id/ENSGALP00010019427.1" } ] } }, { "isoform_ac": "F1NGS8-1", "url": "https://www.uniprot.org/uniprotkb/F1P011/entry#F1NGS8-1", "sequence": { "sequence": "MATITCNRFTEEYQLFEELGKGAFSIVRRCVKVLAGQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGDQQAWFGFAGTPGYLSPEVLRKDPYGKAVDLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPSKRITAAEALKHPWISHRATVASCMHRQETVDCLKKFNARRKLKGAILTTMLATRNFSGGKSGGNKKNDGVKKRKSSSSVQLMESSESTNTTIEDEDTKVRKQEIIKVTEQLIEAISNGDFESYTKMCDPGMTAFEPEALGNLVEGLDFHRFYFENLWSRNSKPVHTTILNPHIHLMGDESACIAYIRITQYVDAGGIPRTAQSEETRIWHRRDGKWQIVHFHRSGAPSVLPQ", "length": 489, "header": "tr|F1NGS8-1|F1NGS8_CHICK Computationally mapped isoform of calcium/calmodulin-dependent protein kinase OS=Gallus gallus OX=9031 GN=CAMK2A PE=3 SV=4 CANONICAL=F1P011-1" }, "locus": { "chromosome": "13", "start_pos": 12815653, "end_pos": 12795871, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032768.1", "url": "https://www.ensembl.org/id/ENSGALT00010032768.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019412.1", "url": "https://www.ensembl.org/id/ENSGALP00010019412.1" } ] } }, { "isoform_ac": "F1P011-1", "url": "https://www.uniprot.org/uniprotkb/F1P011/entry#F1P011-1", "sequence": { "sequence": "MATITCNRFTEEYQLFEELGKGAFSIVRRCVKVLAGQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGDQQAWFGFAGTPGYLSPEVLRKDPYGKAVDLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPSKRITAAEALKHPWISHRATVASCMHRQETVDCLKKFNARRKLKGAILTTMLATRNFSGGKSGGNKKNDGVKESSESTNTTIEDEDTKVRKQEIIKVTEQLIEAISNGDFESYTKMCDPGMTAFEPEALGNLVEGLDFHRFYFENLWSRNSKPVHTTILNPHIHLMGDESACIAYIRITQYVDAGGIPRTAQSEETRIWHRRDGKWQIVHFHRSGAPSVLPQ", "length": 478, "header": "tr|F1P011-1|F1P011_CHICK Isoform 1 of calcium/calmodulin-dependent protein kinase OS=Gallus gallus OX=9031 GN=CAMK2A PE=3 SV=5 CANONICAL=F1P011-1" }, "locus": { "chromosome": "13", "start_pos": 12815653, "end_pos": 12795871, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032751.1", "url": "https://www.ensembl.org/id/ENSGALT00010032751.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019402.1", "url": "https://www.ensembl.org/id/ENSGALP00010019402.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 176, "start_aa": "Thr", "end_pos": 176, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr176", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:374175", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:374175", "resource": "KEGG Pathway" }, { "id": "R-GGA-3371571", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3371571", "resource": "Reactome", "description": "HSF1-dependent transactivation" }, { "id": "R-GGA-4086398", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-4086398", "resource": "Reactome", "description": "Ca2+ pathway" }, { "id": "R-GGA-438066", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-438066", "resource": "Reactome", "description": "Unblocking of NMDA receptors, glutamate binding and activation" }, { "id": "R-GGA-5673001", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5673001", "resource": "Reactome", "description": "RAF/MAP kinase cascade" }, { "id": "R-GGA-877300", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-877300", "resource": "Reactome", "description": "Interferon gamma signaling" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3Q1MKC7-1", "protein_name": "calcium/calmodulin-dependent protein kinase", "gene_name": "CAMK2A", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MATITCTRFTEEYQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGTPGYLSPEVLRKDPYGKPVDLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPSKRITAAEALKHPWISHRSTVASCMHRQETVDCLKKFNARRKLKGAILTTMLATRNFSGGKSGGNKKNDGVKKRKSSSSVQLMESSESTNTTIEDEDTKVRKQEIIKVTEQLIEAISNGDFESYTKMCDPGMTAFEPEALGNLVEGLDFHRFYFENLWSRNSKPVHTTILNPHIHLMGDESACIAYIRITQYLDAGGIPRTAQSEETRVWHRRDGKWQIVHFHRSGAPSVLPH", "length": 489 }, "evidence": [ { "id": "F1P011", "url": "https://omabrowser.org/oma/group/F1P011/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1RL74-1", "protein_name": "calcium/calmodulin-dependent protein kinase", "gene_name": "CAMK2A", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MATITCTRFTEEYQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGTPGYLSPEVLRKDPYGKPVDLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPSKRITAAEALKHPWISHRSTVASCMHRQETVDCLKKFNARRKLKGAILTTMLATRNFSGGKSGGNKKNDGVKKRKSSSSVQLMESSESTNTTIEDEDTKVRKQEIIKVTEQLIEAISNGDFESYTKMCDPGMTAFEPEALGNLVEGLDFHRFYFENLWSRNSKPVHTTILNPHIHLMGDESACIAYIRITQYLDAGGIPRTAQSEETRVWHRRDGKWQIVHFHRSGAPSVLPH", "length": 489 }, "evidence": [ { "id": "F1P011", "url": "https://omabrowser.org/oma/group/F1P011/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P11275-1", "protein_name": "Calcium/calmodulin-dependent protein kinase type II subunit alpha", "gene_name": "Camk2a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MATITCTRFTEEYQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGTPGYLSPEVLRKDPYGKPVDLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPSKRITAAEALKHPWISHRSTVASCMHRQETVDCLKKFNARRKLKGAILTTMLATRNFSGGKSGGNKKNDGVKESSESTNTTIEDEDTKVRKQEIIKVTEQLIEAISNGDFESYTKMCDPGMTAFEPEALGNLVEGLDFHRFYFENLWSRNSKPVHTTILNPHIHLMGDESACIAYIRITQYLDAGGIPRTAQSEETRVWHRRDGKWQIVHFHRSGAPSVLPH", "length": 478 }, "evidence": [ { "id": "F1P011", "url": "https://omabrowser.org/oma/group/F1P011/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P11798-1", "protein_name": "Calcium/calmodulin-dependent protein kinase type II subunit alpha", "gene_name": "Camk2a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MATITCTRFTEEYQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGTPGYLSPEVLRKDPYGKPVDLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPSKRITAAEALKHPWISHRSTVASCMHRQETVDCLKKFNARRKLKGAILTTMLATRNFSGGKSGGNKKNDGVKESSESTNTTIEDEDTKVRKQEIIKVTEQLIEAISNGDFESYTKMCDPGMTAFEPEALGNLVEGLDFHRFYFENLWSRNSKPVHTTILNPHIHLMGDESACIAYIRITQYLDAGGIPRTAQSEETRVWHRRDGKWQIVHFHRSGAPSVLPH", "length": 478 }, "evidence": [ { "id": "F1P011", "url": "https://omabrowser.org/oma/group/F1P011/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9UQM7-1", "protein_name": "Calcium/calmodulin-dependent protein kinase type II subunit alpha", "gene_name": "CAMK2A", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MATITCTRFTEEYQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGTPGYLSPEVLRKDPYGKPVDLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPSKRITAAEALKHPWISHRSTVASCMHRQETVDCLKKFNARRKLKGAILTTMLATRNFSGGKSGGNKKSDGVKESSESTNTTIEDEDTKVRKQEIIKVTEQLIEAISNGDFESYTKMCDPGMTAFEPEALGNLVEGLDFHRFYFENLWSRNSKPVHTTILNPHIHLMGDESACIAYIRITQYLDAGGIPRTAQSEETRVWHRRDGKWQIVHFHRSGAPSVLPH", "length": 478 }, "evidence": [ { "id": "F1P011", "url": "https://omabrowser.org/oma/group/F1P011/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "calmodulin binding", "id": "GO:0005516", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005516", "evidence": [ { "database": "UniProtKB", "id": "F1P011", "url": "https://www.uniprot.org/uniprotkb/F1P011" } ], "pmid": "" }, { "name": "calcium/calmodulin-dependent protein kinase activity", "id": "GO:0004683", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004683", "evidence": [ { "database": "UniProtKB", "id": "F1P011", "url": "https://www.uniprot.org/uniprotkb/F1P011" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "F1P011", "url": "https://www.uniprot.org/uniprotkb/F1P011" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1P011", "url": "https://www.uniprot.org/uniprotkb/F1P011" } ], "pmid": "" }, { "name": "postsynaptic density", "id": "GO:0014069", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0014069", "evidence": [ { "database": "UniProtKB", "id": "F1P011", "url": "https://www.uniprot.org/uniprotkb/F1P011" } ], "pmid": "" }, { "name": "neuron projection", "id": "GO:0043005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043005", "evidence": [ { "database": "UniProtKB", "id": "F1P011", "url": "https://www.uniprot.org/uniprotkb/F1P011" } ], "pmid": "" }, { "name": "organelle", "id": "GO:0043226", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043226", "evidence": [ { "database": "UniProtKB", "id": "F1P011", "url": "https://www.uniprot.org/uniprotkb/F1P011" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "regulation of protein localization to plasma membrane", "id": "GO:1903076", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903076", "evidence": [ { "database": "UniProtKB", "id": "F1P011", "url": "https://www.uniprot.org/uniprotkb/F1P011" } ], "pmid": "" }, { "name": "regulation of neuronal synaptic plasticity", "id": "GO:0048168", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048168", "evidence": [ { "database": "UniProtKB", "id": "F1P011", "url": "https://www.uniprot.org/uniprotkb/F1P011" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 312, "end_pos": 314, "annotation": "n_glycosylation_sequon" }, { "start_pos": 335, "end_pos": 337, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "17989", "name": "", "equation": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q6U1I9-1", "A0A8V0XNJ2-1", "A0A8V0ZUL0-1", "A0A8V0ZT63-1", "A0A8V1ACW2-1", "A0A8V0Z1X0-1", "A0A8V0YHN2-1", "A0A8V0YMN5-1", "A0A8V0Z807-1", "A0A8V0Z930-1", "A0A8V0YFR6-1", "A0A1D5P0M9-1", "A0A8V0ZBN6-1", "A0A3Q2U9U9-1", "A0A8V0YXZ5-1", "A0A8V0ZSP4-1", "A0A8V0ZXQ9-1", "A0A8V0ZZV3-1", "A0A8V1ADF0-1", "A0A8V0ZFT3-1", "A0A8V0ZA45-1", "A0A8V0ZB33-1", "A0A8V0ZD70-1", "A0A8V0Z8T4-1", "R4GIN8-1", "A0A8V0ZK64-1", "A0A8V0ZC16-1", "A0A8V0ZWW1-1", "E1BY69-1", "A0A8V0ZDW9-1", "A0A8V0ZKA2-1", "A0A3Q3B2F1-1", "F1P356-1", "A0A8V1AHA8-1", "Q8QFP8-1", "F1P011-1", "A0A8V0YKK3-1", "A0A1D5NWT4-1", "A0A1D5PMQ7-1", "E1BWA3-1", "F1NVF2-1", "A0A1D5PXN4-1", "A0A3Q2TY19-1", "A0A3Q2U592-1", "A0A8V0XCV5-1", "A0A1D5P8A9-1", "A0A1D5PMG2-1", "A0A8V0X1Q7-1", "A0A8V0Y935-1", "A0A8V0YM96-1", "A0A8V0YF83-1", "A0A8V0YJP9-1", "A0A8V1AKW4-1", "A0A8V0ZSB4-1", "F1NBT0-1", "P18652-1", "P21868-1", "P21869-1", "P53666-1", "P79996-1", "Q5F3W3-1", "Q5ZJS0-1", "Q5ZKN1-1", "Q5ZLL1-1", "A0A8V0XCS0-1", "A0A8V0XNK8-1", "A0A8V0XLV6-1", "A0A8V0XDR5-1", "E1BYH2-1", "E1BQN6-1", "A0A8V0XU71-1", "Q5ZJH6-1", "A0A8V0Y3D1-1", "A0A8V0Y7C3-1", "A0A8V0YCY4-1", "A0A8V0YIV6-1", "A0A8V0YK18-1", "A0A8V0YM22-1", "A0A8V0YTN5-1", "A0A8V0YTP2-1", "Q5F3L1-1", "A0A8V0Y3L2-1", "A0A8V0YCY8-1", "A0A8V0Y9Q1-1", "A0A8V0ZD48-1", "A0A8V0ZD60-1", "A0A8V0ZBZ2-1", "A0A8V0Z9J0-1", "A0A8V1ABF3-1", "Q8AYC9-1", "A0A8V0Z927-1", "A0A8V1A2T9-1", "Q5ZKI0-1", "Q7T0B1-1", "P10741-1", "A0A8V0YFH4-1", "E1C848-1", "A0A8V0X8M1-1", "E1BW33-1", "A0A8V0Z283-1", "A0A8V0Z157-1", "A0A3Q2U4X3-1", "A0A8V0XW11-1", "E1BUG0-1", "A0A8V1ABP4-1", "A0A8V1AJA4-1", "A0A8V1AEH4-1", "F1NJH1-1", "A0A8V1AMK5-1", "A0A3Q2TRY2-1", "A0A8V0X3D6-1", "A0A1D5PD64-1", "A0A8V0XQ97-1", "R4GJB8-1", "A0A8V0X5Z8-1", "A0A8V0XG21-1", "A0A8V0XB58-1", "A0A8V0XMX8-1", "A0A8V0XQS0-1", "A0A8V0XW29-1", "A0A8V0Y074-1", "A0A8V0XXB8-1", "A0A8V0XQ14-1", "A0A8V0XMT1-1", "A0A8V0Y457-1", "A0A8V0Y823-1", "A0A8V0Y4L8-1", "A0A8V0XND6-1", "A0A8V0YZ74-1", "A0A8V0YTI1-1", "A0A8V0YLV1-1", "A0A8V0Z2E3-1", "A0A8V0YCV9-1", "A0A8V0YSH3-1", "A0A8V0YYX2-1", "A0A8V0YZY4-1", "Q5ZIU3-1", "A0A8V0YZK0-1", "A0A8V0ZKM9-1", "A0A8V0ZWC7-1", "A0A8V1A1Y7-1", "A0A8V1A069-1", "A0A8V0ZI32-1", "A0A8V0ZH91-1", "E1BQV7-1", "A0A8V0ZRX1-1", "A0A8V0ZUU9-1", "A0A8V1A0Y8-1", "A0A8V1A7E9-1", "A0A8V1A7E0-1", "A0A8V1A3T8-1", "A0A8V1A9S5-1", "A0A8V1A7M0-1", "A0A8V1A675-1", "A0A8V1A1P3-1", "A0A8V1ADT4-1", "E1BWT0-1", "A0A8V1ACF6-1", "A0A8V1ADN9-1", "A0A8V1AM12-1", "A0A8V1A4Q4-1", "Q90891-1", "A0A1D5P517-1", "F1NB57-1", "F1NUX4-1", "A0A8V0ZZE4-1", "P05625-1", "P13863-1", "P67962-1", "Q04982-2", "Q0GGW5-1", "Q6XUX0-1", "Q8QGX4-1", "Q9I9E0-1", "Q9IA88-1", "Q5ZJK4-1", "A0A1D5PTJ8-1", "E1C2I2-1", "F1NCX7-1", "F1NKW3-1", "A0A8V1A0W4-1", "A0A8V1A4J8-1", "A0A8V1ACK0-1", "F1NCY7-1", "A0A8V0X6T4-1", "A0A8V0ZFM2-1", "A0A8V0XUM6-1", "A0A8V0XEA3-1", "A0A8V1AIY7-1", "A0A8V0YHH2-1", "A0A3Q2UI52-1", "A0A8V0ZZK5-1", "A0A8V0ZPX2-1", "A0A8V1ACB5-1", "A0A8V0YDH4-1", "A0A8V1AFS4-1", "A0A8V1AH12-1", "A0A8V0YRC9-1", "A0A8V0ZQT5-1", "A0A8V0ZFP1-1", "E1C764-1", "A0A1D5PUY5-1", "F1P4G3-1", "A0A8V0ZMK1-1", "A0A8V0Y2I5-1", "A0A8V0ZLU3-1", "A0A8V0ZNP7-1", "A0A8V0Z2Z3-1", "A0A8V0YNI5-1", "Q90771-1", "A0A8V0X4P0-1", "A0A8V0X7R2-1", "A0A3Q3A664-1", "A0A8V0YGW2-1", "E1C581-1", "A0A8V1AC40-1", "A0A3Q2TUS7-1", "A0A1D5PA08-1", "A0A8V0XFW1-1", "A0A8V0XAH9-1", "A0A8V1A4A1-1", "A0A8V0ZD40-1", "A0A8V0Z6T1-1", "A0A8V1A4V7-1", "E1C093-1", "A0A8V0YZF2-1", "E1BX69-1", "A0A8V0XI18-1", "A0A8V0Y955-1", "A0A1D5PB73-1", "A0A1D5PV76-1", "A0A1D5PX90-1", "A0A1L1RWI9-1", "A0A3Q2TV19-1", "A0A3Q2UF44-1", "A0A8V0X4Q3-1", "A0A8V0Z124-1", "A0A8V0Z6K4-1", "A0A8V1AE45-1", "A0A8V0YZV9-1", "A0A8V0YYZ3-1", "A0A8V0ZUC6-1", "A0A8V0ZUU8-1", "A0A8V1AG70-1", "F1NA68-1", "F1NLR7-1", "A0A8V0Y6K1-1", "A0A8V0XS42-1", "A0A8V0YRN4-1", "A0A8V0YFP8-1", "A0A8V1A7P9-1", "A0A1D5PRN8-1", "A0A3Q3AAD7-1", "A0A3Q2TWZ8-1", "A0A8V0XBZ0-1", "A0A8V0XFX2-1", "A0A8V0YFL1-1", "A0A8V0YTL9-1", "A0A8V0YMB3-1", "A0A8V0X2Y2-1", "A0A8V0XCY6-1", "A0A3Q2UI62-1", "A0A8V0Y241-1", "A0A8V0Z8G2-1", "A0A8V1ABR8-1", "A0A8V1AP60-1", "A0A8V0YZM1-1", "A0A8V0ZB38-1", "A0A8V0Z466-1", "A0A8V0ZA06-1", "A0A8V1AMQ2-1", "A0A8V0ZGY3-1", "A0A8V0ZQJ2-1", "A0A8V0ZYU6-1", "A0A8V1A513-1", "A0A8V0XE48-1", "A0A8V0XQQ4-1", "A0A8V0XKG0-1" ], "evidence": [ { "id": "17989", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/17989" } ] }, { "id": "46608", "name": "", "equation": "L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A1D5PUY5-1", "Q6U1I9-1", "A0A8V0XNJ2-1", "A0A8V0ZUL0-1", "A0A8V0ZT63-1", "A0A8V1ACW2-1", "A0A8V0Z1X0-1", "A0A8V0YHN2-1", "A0A8V0YMN5-1", "A0A8V0Z807-1", "A0A8V0Z930-1", "A0A8V0YFR6-1", "A0A1D5P0M9-1", "A0A8V0ZBN6-1", "A0A3Q2U9U9-1", "A0A8V0YRC9-1", "A0A8V0YXZ5-1", "A0A8V0ZSP4-1", "A0A8V0ZXQ9-1", "A0A8V0ZZV3-1", "A0A8V1ADF0-1", "A0A8V0ZFT3-1", "A0A8V0ZA45-1", "A0A8V0ZB33-1", "A0A8V0ZD70-1", "A0A8V0Z8T4-1", "R4GIN8-1", "A0A8V0ZK64-1", "A0A8V0ZC16-1", "A0A8V0ZWW1-1", "E1BY69-1", "A0A8V0ZDW9-1", "A0A8V0ZKA2-1", "A0A3Q3B2F1-1", "F1P356-1", "A0A8V1AHA8-1", "Q8QFP8-1", "F1P011-1", "A0A8V0YKK3-1", "A0A1D5NWT4-1", "A0A1D5PMQ7-1", "E1BWA3-1", "F1NVF2-1", "A0A1D5PXN4-1", "A0A3Q2TY19-1", "A0A3Q2U592-1", "A0A8V0XCV5-1", "A0A1D5P8A9-1", "A0A1D5PMG2-1", "A0A8V0X1Q7-1", "A0A8V0Y935-1", "A0A8V0YM96-1", "A0A8V0YF83-1", "A0A8V0YJP9-1", "A0A8V1AKW4-1", "A0A1D5P517-1", "A0A8V0ZSB4-1", "F1NBT0-1", "P18652-1", "P21868-1", "P21869-1", "P53666-1", "P79996-1", "Q5F3W3-1", "Q5ZJS0-1", "Q5ZKN1-1", "Q5ZLL1-1", "A0A8V0XCS0-1", "A0A8V0XNK8-1", "A0A8V0XLV6-1", "A0A8V0XDR5-1", "E1BYH2-1", "F1NB57-1", "E1BQN6-1", "A0A8V0XU71-1", "Q5ZJH6-1", "A0A8V0Y3D1-1", "A0A8V0Y7C3-1", "A0A8V0YCY4-1", "A0A8V0YIV6-1", "A0A8V0YK18-1", "A0A8V0YM22-1", "A0A8V0YTN5-1", "A0A8V0YTP2-1", "Q5F3L1-1", "A0A8V0XU96-1", "E1C6T4-1", "A0A8V0Y3L2-1", "A0A8V0YCY8-1", "A0A8V0Y9Q1-1", "A0A8V0ZD48-1", "A0A8V0ZD60-1", "A0A8V0ZBZ2-1", "A0A8V0Z9J0-1", "A0A8V1ABF3-1", "Q8AYC9-1", "A0A8V0Z927-1", "A0A8V1A2T9-1", "Q5ZKI0-1", "Q7T0B1-1", "P10741-1", "A0A8V1AMK5-1", "P67962-1", "A0A8V0YFH4-1", "E1C848-1", "A0A8V0X8M1-1", "E1BW33-1", "A0A8V0Z283-1", "A0A8V0Z157-1", "A0A3Q2U4X3-1", "A0A8V0XW11-1", "E1BUG0-1", "A0A8V1ABP4-1", "A0A8V1AJA4-1", "A0A8V1AEH4-1", "F1NJH1-1", "A0A3Q2TRY2-1", "A0A8V0X3D6-1", "A0A1D5PD64-1", "A0A8V0XQ97-1", "R4GJB8-1", "A0A8V0X5Z8-1", "A0A8V0XG21-1", "A0A8V0XB58-1", "A0A8V0XMX8-1", "A0A8V0XQS0-1", "A0A8V0XW29-1", "A0A8V0Y074-1", "A0A8V0XXB8-1", "A0A8V0XQ14-1", "A0A8V0XI18-1", "A0A8V0XMT1-1", "A0A8V0Y457-1", "A0A8V0Y823-1", "A0A8V0Y4L8-1", "A0A8V0XND6-1", "A0A8V0Y8X9-1", "A0A8V0YZ74-1", "A0A8V0YTI1-1", "A0A8V0YLV1-1", "A0A8V0Z2E3-1", "A0A8V0YCV9-1", "A0A8V0YSH3-1", "A0A8V0YYX2-1", "A0A8V0YZY4-1", "Q5ZIU3-1", "A0A8V0YZK0-1", "A0A8V0ZKM9-1", "A0A8V0ZWC7-1", "A0A8V1A1Y7-1", "A0A8V1A069-1", "A0A8V0ZI32-1", "A0A8V0ZH91-1", "E1BQV7-1", "A0A8V0ZRX1-1", "A0A8V0ZUU9-1", "A0A8V1A0Y8-1", "A0A8V1A7E9-1", "A0A8V1A7E0-1", "A0A8V1A3T8-1", "A0A8V1A9S5-1", "A0A8V1A7M0-1", "A0A8V1A675-1", "A0A8V1A1P3-1", "A0A8V1ADT4-1", "E1BWT0-1", "A0A8V1ACF6-1", "A0A8V1ADN9-1", "A0A8V1AM12-1", "A0A8V1A4Q4-1", "Q90891-1", "F1NUX4-1", "A0A8V0ZZE4-1", "P05625-1", "P13863-1", "Q04982-2", "Q0GGW5-1", "Q6XUX0-1", "Q8QGX4-1", "Q9I9E0-1", "Q9IA88-1", "Q5ZJK4-1", "A0A1D5PTJ8-1", "E1C2I2-1", "F1NCX7-1", "F1NKW3-1", "A0A8V1A0W4-1", "A0A8V1A4J8-1", "A0A8V1ACK0-1", "F1NCY7-1", "A0A8V0X6T4-1", "A0A8V0XUM6-1", "A0A8V0XEA3-1", "A0A8V0YHH2-1", "A0A3Q2UI52-1", "A0A8V0ZZK5-1", "A0A8V0ZPX2-1", "A0A8V1ACB5-1", "A0A8V0YDH4-1", "A0A8V1AFS4-1", "A0A8V1AH12-1", "A0A8V0ZQT5-1", "A0A8V0ZFP1-1", "E1C764-1", "F1P4G3-1", "A0A8V0Y2I5-1", "A0A8V0ZLU3-1", "A0A8V0ZNP7-1", "A0A8V0Z2Z3-1", "A0A8V0YNI5-1", "Q90771-1", "A0A8V0X4P0-1", "A0A8V0X7R2-1", "A0A3Q3A664-1", "A0A8V0YGW2-1", "E1C581-1", "A0A8V1AC40-1", "A0A3Q2TUS7-1", "A0A1D5PA08-1", "A0A8V0XFW1-1", "A0A8V0XAH9-1", "A0A8V0ZFM2-1", "A0A8V1A4A1-1", "A0A8V0ZD40-1", "A0A8V0Z6T1-1", "A0A8V1A4V7-1", "A0A8V0YZF2-1", "E1BX69-1", "A0A8V0Y955-1", "A0A1D5PB73-1", "A0A1D5PV76-1", "A0A1D5PX90-1", "A0A1L1RWI9-1", "A0A3Q2TV19-1", "A0A3Q2UF44-1", "A0A8V0X4Q3-1", "A0A8V0Z124-1", "A0A8V0Z6K4-1", "A0A8V1AIY7-1", "A0A8V1AE45-1", "A0A8V0YZV9-1", "A0A8V0YYZ3-1", "A0A8V0ZUC6-1", "A0A8V0ZUU8-1", "A0A8V1AG70-1", "F1NA68-1", "F1NLR7-1", "A0A8V0Y6K1-1", "A0A8V0XS42-1", "A0A8V0YRN4-1", "A0A8V0YFP8-1", "A0A8V1A7P9-1", "A0A1D5PRN8-1", "A0A3Q3AAD7-1", "A0A3Q2TWZ8-1", "A0A8V0XBZ0-1", "A0A8V0XFX2-1", "A0A8V0YFL1-1", "A0A8V0YTL9-1", "A0A8V0YMB3-1", "A0A8V0X2Y2-1", "A0A8V0XCY6-1", "A0A3Q2UI62-1", "A0A8V0Y241-1", "A0A8V0Z8G2-1", "A0A8V1ABR8-1", "A0A8V1AP60-1", "A0A8V0YZM1-1", "A0A8V0ZB38-1", "A0A8V0Z466-1", "A0A8V0ZA06-1", "A0A8V1AMQ2-1", "A0A8V0ZGY3-1", "A0A8V0ZQJ2-1", "A0A8V0ZYU6-1", "A0A8V1A513-1", "A0A8V0XE48-1", "A0A8V0XKG0-1" ], "evidence": [ { "id": "46608", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/46608" } ] }, { "id": "R-GGA-432164", "name": "Ca2+ influx into the post-synaptic cell", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XB58-1", "F1P011-1", "A0A8V0ZB33-1" ], "evidence": [ { "id": "R-GGA-432164", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-432164" } ] }, { "id": "R-GGA-4332356", "name": "CAMK2 binds MAP3K7", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1P011-1", "A0A8V0XCV5-1" ], "evidence": [ { "id": "R-GGA-4332356", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-4332356" } ] }, { "id": "R-GGA-438037", "name": "Membrane depolarization upon activation of Ca impermeable AMPA receptors", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XB58-1", "F1P011-1", "A0A8V0ZB33-1" ], "evidence": [ { "id": "R-GGA-438037", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-438037" } ] }, { "id": "R-GGA-5082387", "name": "Phosphorylation of HSF1 at Ser230 induces transactivation", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XB58-1", "F1P011-1", "A0A8V0ZB33-1" ], "evidence": [ { "id": "R-GGA-5082387", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5082387" } ] }, { "id": "R-GGA-5672965", "name": "RAS GEFs promote RAS nucleotide exchange", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XB58-1", "F1P011-1", "A0M8T9-1", "A0A8V0XB17-1", "A0A8V0YLC3-1", "A0A8V0YWD3-1", "A0A8V0Z7L6-1", "F1NCL8-1", "Q5F352-1", "A0A8V0XNF4-1", "A0A8V0XQ80-1", "A0A8V0YGR1-1", "A0A8V0YNY4-1", "A0A8V0YYZ7-1", "A0A8V0ZXS7-1", "A0A8V1A7N1-1", "A0A8V0YZE5-1", "A0A8V0ZB33-1", "A0A3Q2U639-1", "A0A3Q2UKD3-1", "P08642-1", "Q08156-1", "A0A8V0YIT6-1" ], "evidence": [ { "id": "R-GGA-5672965", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5672965" } ] }, { "id": "R-GGA-909552", "name": "Phosphorylation of STAT1 at Ser727", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XB58-1", "F1P011-1", "A0A8V0ZSN8-1", "A0A8V0YNY4-1", "A0A8V0ZB33-1", "A0A1D5PXN4-1" ], "evidence": [ { "id": "R-GGA-909552", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-909552" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A1D5NWT4", "gene_name": "RPS6KA3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5NWT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NWT4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A1D5NWT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NWT4" } ] } ] }, { "uniprot_ac": "A0A1D5P0M9", "gene_name": "MAP3K13", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5P0M9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P0M9" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A1D5P0M9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P0M9" } ] } ] }, { "uniprot_ac": "A0A1D5P517", "gene_name": "PLK3", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5P517", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P517" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0A1D5P517", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P517" } ] } ] }, { "uniprot_ac": "A0A1D5P8A9", "gene_name": "SNRK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5P8A9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P8A9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A1D5P8A9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P8A9" } ] } ] }, { "uniprot_ac": "A0A1D5PA08", "gene_name": "STK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PA08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PA08" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A1D5PA08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PA08" } ] } ] }, { "uniprot_ac": "A0A1D5PB73", "gene_name": "CASK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PB73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PB73" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A1D5PB73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PB73" } ] } ] }, { "uniprot_ac": "A0A1D5PD64", "gene_name": "MAP2K3", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PD64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PD64" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A1D5PD64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PD64" } ] } ] }, { "uniprot_ac": "A0A1D5PMG2", "gene_name": "DCLK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PMG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PMG2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A1D5PMG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PMG2" } ] } ] }, { "uniprot_ac": "A0A1D5PMQ7", "gene_name": "STK40", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PMQ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PMQ7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A1D5PMQ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PMQ7" } ] } ] }, { "uniprot_ac": "A0A1D5PRN8", "gene_name": "DAPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PRN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRN8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A1D5PRN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRN8" } ] } ] }, { "uniprot_ac": "A0A1D5PTJ8", "gene_name": "MAP3K5", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PTJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PTJ8" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A1D5PTJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PTJ8" } ] } ] }, { "uniprot_ac": "A0A1D5PUY5", "gene_name": "PRKCB", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PUY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PUY5" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A1D5PUY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PUY5" } ] } ] }, { "uniprot_ac": "A0A1D5PV76", "gene_name": "STK17A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PV76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PV76" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A1D5PV76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PV76" } ] } ] }, { "uniprot_ac": "A0A1D5PX90", "gene_name": "KSR2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PX90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PX90" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A1D5PX90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PX90" } ] } ] }, { "uniprot_ac": "A0A1D5PXN4", "gene_name": "PRKCD", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PXN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PXN4" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A1D5PXN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PXN4" } ] } ] }, { "uniprot_ac": "A0A1L1RWI9", "gene_name": "CAMK4", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1L1RWI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RWI9" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A1L1RWI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RWI9" } ] } ] }, { "uniprot_ac": "A0A3Q2TRY2", "gene_name": "TAOK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q2TRY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TRY2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q2TRY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TRY2" } ] } ] }, { "uniprot_ac": "A0A3Q2TUS7", "gene_name": "TLK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q2TUS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TUS7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q2TUS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TUS7" } ] } ] }, { "uniprot_ac": "A0A3Q2TV19", "gene_name": "UHMK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q2TV19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TV19" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q2TV19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TV19" } ] } ] }, { "uniprot_ac": "A0A3Q2TWZ8", "gene_name": "MAP3K20", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q2TWZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TWZ8" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A3Q2TWZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TWZ8" } ] } ] }, { "uniprot_ac": "A0A3Q2TY19", "gene_name": "MAPK8", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q2TY19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TY19" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A3Q2TY19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TY19" } ] } ] }, { "uniprot_ac": "A0A3Q2U4X3", "gene_name": "AKT1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q2U4X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U4X3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q2U4X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U4X3" } ] } ] }, { "uniprot_ac": "A0A3Q2U592", "gene_name": "DCLK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { 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"url": "https://www.uniprot.org/uniprotkb/A0A8V0X1Q7" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0X1Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X1Q7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0X1Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X1Q7" } ] } ] }, { "uniprot_ac": "A0A8V0X2Y2", "gene_name": "MAPK12", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X2Y2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X2Y2" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0X2Y2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X2Y2" } ] } ] }, { "uniprot_ac": "A0A8V0X3D6", "gene_name": "LOC100858386", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X3D6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X3D6" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0X3D6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X3D6" } ] } ] }, { "uniprot_ac": "A0A8V0X4P0", "gene_name": "CDKL5", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X4P0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X4P0" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0X4P0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X4P0" } ] } ] }, { "uniprot_ac": "A0A8V0X4Q3", "gene_name": "ICK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X4Q3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X4Q3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0X4Q3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X4Q3" } ] } ] }, { "uniprot_ac": "A0A8V0X5Z8", "gene_name": "NEK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X5Z8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X5Z8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0X5Z8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X5Z8" } ] } ] }, { "uniprot_ac": "A0A8V0X6T4", "gene_name": "LOC107050692", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X6T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X6T4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0X6T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X6T4" } ] } ] }, { "uniprot_ac": "A0A8V0X7R2", "gene_name": "SBK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X7R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X7R2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0X7R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X7R2" } ] } ] }, { "uniprot_ac": "A0A8V0X8M1", "gene_name": "TRIO", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X8M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X8M1" } ] }, { "ec_number": 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O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XFW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XFW1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XFW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XFW1" } ] } ] }, { "uniprot_ac": "A0A8V0XFX2", "gene_name": "NEK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XFX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XFX2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XFX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XFX2" } ] } ] }, { "uniprot_ac": "A0A8V0XG21", "gene_name": "LOC107050335", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XG21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XG21" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XG21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XG21" } ] } ] }, { "uniprot_ac": "A0A8V0XI18", "gene_name": "ATM", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XI18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XI18" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XI18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XI18" } ] } ] }, { "uniprot_ac": "A0A8V0XKG0", "gene_name": "NEK9", "activity": [ { "ec_number": "2.7.11.38", "activity": "L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XKG0", "database": "UniProtKB", "url": 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{ "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XQ14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ14" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0A8V0XQ14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ14" } ] } ] }, { "uniprot_ac": "A0A8V0XQ80", "gene_name": "FLT3", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XQ80", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ80" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0XQ80", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ80" } ] } ] }, { "uniprot_ac": "A0A8V0XQ97", "gene_name": "CDK14", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XQ97", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ97" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0XQ97", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ97" } ] } ] }, { "uniprot_ac": "A0A8V0XQQ4", "gene_name": "NME7", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQQ4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQQ4" } ] } ] }, { "uniprot_ac": "A0A8V0XQS0", "gene_name": "STK24", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XQS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQS0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XQS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQS0" } ] } ] }, { "uniprot_ac": "A0A8V0XS42", "gene_name": "MAP3K4", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XS42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XS42" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0XS42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XS42" } ] } ] }, { "uniprot_ac": "A0A8V0XU71", "gene_name": "MYO3A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XU71", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XU71" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XU71", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XU71" } ] } ] }, { "uniprot_ac": "A0A8V0XU96", "gene_name": "PRKD1", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XU96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XU96" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V0XU96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XU96" } ] } ] }, { "uniprot_ac": "A0A8V0XUM6", "gene_name": "LATS1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XUM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XUM6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XUM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XUM6" } ] } ] }, { "uniprot_ac": "A0A8V0XW11", "gene_name": "RPS6KA2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XW11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XW11" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XW11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XW11" } ] } ] }, { "uniprot_ac": "A0A8V0XW29", "gene_name": "CDKL2", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XW29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XW29" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": 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"database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] }, { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] } ] }, { "uniprot_ac": "A0A8V0Y3D1", "gene_name": "LRRK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", 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"ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YCY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCY8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YCY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCY8" } ] } ] }, { "uniprot_ac": "A0A8V0YDH4", "gene_name": "ALPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YDH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDH4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YDH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDH4" } ] } ] }, { "uniprot_ac": "A0A8V0YF83", "gene_name": "WNK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YF83", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF83" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YF83", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF83" } ] } ] }, { "uniprot_ac": "A0A8V0YFH4", "gene_name": "NRK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YFH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFH4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YFH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFH4" } ] } ] }, { "uniprot_ac": "A0A8V0YFL1", "gene_name": "CDK19", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YFL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFL1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0YFL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFL1" } ] } ] }, { "uniprot_ac": "A0A8V0YFP8", "gene_name": "RIPK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YFP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFP8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YFP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFP8" } ] } ] }, { "uniprot_ac": "A0A8V0YFR6", "gene_name": "TNIK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YFR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFR6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YFR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFR6" } ] } ] }, { "uniprot_ac": "A0A8V0YGR1", "gene_name": "RET", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YGR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGR1" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0YGR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGR1" } ] } ] }, { "uniprot_ac": "A0A8V0YGW2", "gene_name": "STK32B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YGW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGW2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YGW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGW2" } ] } ] }, { "uniprot_ac": "A0A8V0YHH2", "gene_name": "STK38L", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YHH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHH2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YHH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHH2" } ] } ] }, { "uniprot_ac": "A0A8V0YHN2", "gene_name": "RPS6KA1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YHN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHN2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YHN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHN2" } ] } ] }, { "uniprot_ac": "A0A8V0YIT6", "gene_name": "ERBB4", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YIT6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIT6" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0YIT6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIT6" } ] } ] }, { "uniprot_ac": "A0A8V0YIV6", "gene_name": "DYRK1A", "activity": [ { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] }, { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] } ] }, { "uniprot_ac": "A0A8V0YJP9", "gene_name": "RIOK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YJP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJP9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YJP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJP9" } ] } ] }, { "uniprot_ac": "A0A8V0YK18", "gene_name": "CDC42BPB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YK18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK18" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YK18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK18" } ] } ] }, { "uniprot_ac": "A0A8V0YKK3", "gene_name": "MAP4K4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YKK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKK3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YKK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKK3" } ] } ] }, { "uniprot_ac": "A0A8V0YLC3", "gene_name": "PDGFRA", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YLC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLC3" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0YLC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLC3" } ] } ] }, { "uniprot_ac": "A0A8V0YLV1", "gene_name": "MARK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YLV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLV1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YLV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLV1" } ] } ] }, { "uniprot_ac": "A0A8V0YM22", "gene_name": "MYO3AL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YM22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM22" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YM22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM22" } ] } ] }, { "uniprot_ac": "A0A8V0YM96", "gene_name": "STK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YM96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM96" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YM96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM96" } ] } ] }, { "uniprot_ac": "A0A8V0YMB3", "gene_name": "STK32A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YMB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMB3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YMB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMB3" } ] } ] }, { "uniprot_ac": "A0A8V0YMN5", "gene_name": "BRAF", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YMN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMN5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YMN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMN5" } ] } ] }, { "uniprot_ac": "A0A8V0YNI5", "gene_name": "NIM1K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YNI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNI5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YNI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNI5" } ] } ] }, { "uniprot_ac": "A0A8V0YNY4", "gene_name": "JAK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YNY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNY4" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0YNY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNY4" } ] } ] }, { "uniprot_ac": "A0A8V0YRC9", "gene_name": "TNK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YRC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRC9" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YRC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRC9" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0YRC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRC9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YRC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRC9" } ] } ] }, { "uniprot_ac": "A0A8V0YRN4", "gene_name": "GAK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YRN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRN4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YRN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRN4" } ] } ] }, { "uniprot_ac": "A0A8V0YSH3", "gene_name": "RPS6KA6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YSH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSH3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YSH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSH3" } ] } ] }, { "uniprot_ac": "A0A8V0YTI1", "gene_name": "TSSK6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTI1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTI1" } ] } ] }, { "uniprot_ac": "A0A8V0YTL9", "gene_name": "VRK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTL9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTL9" } ] } ] }, { "uniprot_ac": "A0A8V0YTN5", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTN5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTN5" } ] } ] }, { "uniprot_ac": "A0A8V0YTP2", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTP2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTP2" } ] } ] }, { "uniprot_ac": "A0A8V0YWD3", "gene_name": "PTPRA", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0YWD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YWD3" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0YWD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YWD3" } ] } ] }, { "uniprot_ac": "A0A8V0YXZ5", "gene_name": "CDC42BPA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YXZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXZ5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YXZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXZ5" } ] } ] }, { "uniprot_ac": "A0A8V0YYX2", "gene_name": "PAK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YYX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYX2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YYX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYX2" } ] } ] }, { "uniprot_ac": "A0A8V0YYZ3", "gene_name": "SPEG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YYZ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYZ3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YYZ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYZ3" } ] } ] }, { "uniprot_ac": "A0A8V0YYZ7", "gene_name": "FGFR3", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YYZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYZ7" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0YYZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYZ7" } ] } ] }, { "uniprot_ac": "A0A8V0YZ74", "gene_name": "MAP2K5", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZ74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZ74" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V0YZ74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZ74" } ] } ] }, { "uniprot_ac": "A0A8V0YZE5", "gene_name": "PDGFRB", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZE5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZE5" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0YZE5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZE5" } ] } ] }, { "uniprot_ac": "A0A8V0YZF2", "gene_name": "PAK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZF2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YZF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZF2" } ] } ] }, { "uniprot_ac": "A0A8V0YZK0", "gene_name": "MAP3K6", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZK0" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0YZK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZK0" } ] } ] }, { "uniprot_ac": "A0A8V0YZM1", "gene_name": "MOK", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZM1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0YZM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZM1" } ] }, { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZM1" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0YZM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZM1" } ] } ] }, { "uniprot_ac": "A0A8V0YZV9", "gene_name": "ATR", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZV9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YZV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZV9" } ] } ] }, { "uniprot_ac": "A0A8V0YZY4", "gene_name": "SBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZY4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YZY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZY4" } ] } ] }, { "uniprot_ac": "A0A8V0Z124", "gene_name": "VRK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z124", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z124" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z124", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z124" } ] } ] }, { "uniprot_ac": "A0A8V0Z157", "gene_name": "MARK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z157", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z157" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z157", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z157" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A8V0Z157", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z157" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z157", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z157" } ] } ] }, { "uniprot_ac": "A0A8V0Z1X0", "gene_name": "MAP4K3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z1X0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1X0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z1X0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1X0" } ] } ] }, { "uniprot_ac": "A0A8V0Z283", "gene_name": "MARK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z283", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z283" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z283", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z283" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A8V0Z283", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z283" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z283", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z283" } ] } ] }, { "uniprot_ac": "A0A8V0Z2E3", "gene_name": "PDIK1L", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z2E3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2E3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z2E3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2E3" } ] } ] }, { "uniprot_ac": "A0A8V0Z2Z3", "gene_name": "AAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z2Z3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2Z3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z2Z3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2Z3" } ] } ] }, { "uniprot_ac": "A0A8V0Z466", "gene_name": "MAP3K19", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z466", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z466" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z466", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z466" } ] } ] }, { "uniprot_ac": "A0A8V0Z6K4", "gene_name": "PIK3R4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z6K4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6K4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z6K4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6K4" } ] } ] }, { "uniprot_ac": "A0A8V0Z6T1", "gene_name": "ERN2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z6T1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6T1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z6T1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6T1" } ] } ] }, { "uniprot_ac": "A0A8V0Z7L6", "gene_name": "FGFR1", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z7L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7L6" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0Z7L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7L6" } ] } ] }, { "uniprot_ac": "A0A8V0Z807", "gene_name": "NEK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z807", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z807" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z807", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z807" } ] } ] }, { "uniprot_ac": "A0A8V0Z8G2", "gene_name": "TTBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z8G2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8G2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z8G2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8G2" } ] } ] }, { "uniprot_ac": "A0A8V0Z8T4", "gene_name": "RPS6KC1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z8T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8T4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z8T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8T4" } ] } ] }, { "uniprot_ac": "A0A8V0Z927", "gene_name": "PINK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z927", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z927" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z927", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z927" } ] } ] }, { "uniprot_ac": "A0A8V0Z930", "gene_name": "CAMK2B", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z930", "database": "UniProtKB", "url": 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"ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0ZA06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA06" } ] } ] }, { "uniprot_ac": "A0A8V0ZA45", "gene_name": "MAP4K5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZA45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA45" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZA45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA45" } ] } ] }, { "uniprot_ac": "A0A8V0ZB33", "gene_name": "CAMK2G", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZB33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB33" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V0ZB33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB33" } ] } ] }, { "uniprot_ac": "A0A8V0ZB38", "gene_name": "CIITA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZB38", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB38" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZB38", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB38" } ] } ] }, { "uniprot_ac": "A0A8V0ZBN6", "gene_name": "MAP2K1", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZBN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBN6" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V0ZBN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBN6" } ] } ] }, { "uniprot_ac": "A0A8V0ZBZ2", "gene_name": "MAP3K9", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZBZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBZ2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0ZBZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBZ2" } ] } ] }, { "uniprot_ac": "A0A8V0ZC16", "gene_name": "KALRN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZC16", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC16" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZC16", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC16" } ] } ] }, { "uniprot_ac": "A0A8V0ZD40", "gene_name": "CDC2L1", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD40" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD40" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A8V0ZD40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD40" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0ZD40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD40" } ] } ] }, { "uniprot_ac": "A0A8V0ZD48", "gene_name": "PRKCE", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD48" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V0ZD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD48" } ] } ] }, { "uniprot_ac": "A0A8V0ZD60", "gene_name": "STK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD60" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZD60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD60" } ] } ] }, { "uniprot_ac": "A0A8V0ZD70", "gene_name": "DCLK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + 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} ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZFT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFT3" } ] } ] }, { "uniprot_ac": "A0A8V0ZGY3", "gene_name": "HIPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZGY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGY3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZGY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGY3" } ] } ] }, { "uniprot_ac": "A0A8V0ZH91", "gene_name": "WNK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZH91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH91" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZH91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH91" } ] } ] }, { "uniprot_ac": "A0A8V0ZI32", "gene_name": "STK16", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZI32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI32" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZI32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI32" } ] } ] }, { "uniprot_ac": "A0A8V0ZK64", "gene_name": "PDPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZK64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK64" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZK64", "database": "UniProtKB", "url": 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H(+).", "evidence": [ { "id": "A0A8V0ZQT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQT5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZQT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQT5" } ] } ] }, { "uniprot_ac": "A0A8V0ZRX1", "gene_name": "SETD6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZRX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRX1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZRX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRX1" } ] }, { "ec_number": "2.1.1.-", "activity": "", "evidence": [ { "id": "A0A8V0ZRX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRX1" } ] } ] }, { "uniprot_ac": "A0A8V0ZSB4", "gene_name": "SIK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZSB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSB4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZSB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSB4" } ] } ] }, { "uniprot_ac": "A0A8V0ZSN8", "gene_name": "JAK1", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZSN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSN8" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0ZSN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSN8" } ] } ] }, { "uniprot_ac": "A0A8V0ZSP4", "gene_name": "PKN2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZSP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSP4" } ] }, { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZSP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSP4" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V0ZSP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSP4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZSP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSP4" } ] } ] }, { "uniprot_ac": "A0A8V0ZT63", "gene_name": "STK25", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZT63", "database": "UniProtKB", "url": 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"database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUU9" } ] } ] }, { "uniprot_ac": "A0A8V0ZWC7", "gene_name": "EIF2AK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZWC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWC7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZWC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWC7" } ] } ] }, { "uniprot_ac": "A0A8V0ZWW1", "gene_name": "MAP3K12", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZWW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWW1" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0ZWW1", "database": "UniProtKB", "url": 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O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A069", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A069" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V1A069", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A069" } ] } ] }, { "uniprot_ac": "A0A8V1A0W4", "gene_name": "ULK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A0W4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0W4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A0W4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0W4" } ] } ] }, { "uniprot_ac": "A0A8V1A0Y8", "gene_name": "MAST2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": 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"ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A3T8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3T8" } ] } ] }, { "uniprot_ac": "A0A8V1A4A1", "gene_name": "CAMKK2", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4A1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4A1" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V1A4A1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4A1" } ] } ] }, { "uniprot_ac": "A0A8V1A4J8", "gene_name": "MAPKAPK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4J8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4J8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A4J8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4J8" } ] } ] }, { "uniprot_ac": "A0A8V1A4Q4", "gene_name": "MAPK3", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4Q4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4Q4" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V1A4Q4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4Q4" } ] } ] }, { "uniprot_ac": "A0A8V1A4V7", "gene_name": "HIPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4V7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4V7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A4V7", "database": "UniProtKB", "url": 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"uniprot_ac": "A0A8V1A7E0", "gene_name": "DYRK3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7E0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E0" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V1A7E0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E0" } ] } ] }, { "uniprot_ac": "A0A8V1A7E9", "gene_name": "SIK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7E9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A7E9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E9" } ] } ] }, { "uniprot_ac": "A0A8V1A7M0", "gene_name": "STK39", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7M0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7M0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A7M0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7M0" } ] } ] }, { "uniprot_ac": "A0A8V1A7N1", "gene_name": "ERBB3", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7N1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7N1" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V1A7N1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7N1" } ] } ] }, { "uniprot_ac": "A0A8V1A7P9", "gene_name": "DCAF1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A7P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P9" } ] } ] }, { "uniprot_ac": "A0A8V1A9S5", "gene_name": "NUAK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A9S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9S5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A9S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9S5" } ] } ] }, { "uniprot_ac": "A0A8V1ABF3", "gene_name": "PRKAA2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] } ] }, { "uniprot_ac": "A0A8V1ABP4", "gene_name": "DSTYK", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABP4" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V1ABP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABP4" } ] } ] }, { "uniprot_ac": "A0A8V1ABR8", "gene_name": "CAMK4L", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABR8" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V1ABR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABR8" } ] } ] }, { "uniprot_ac": "A0A8V1AC40", "gene_name": "CDK18", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AC40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC40" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V1AC40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC40" } ] } ] }, { "uniprot_ac": "A0A8V1ACB5", "gene_name": "MAPK13", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACB5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V1ACB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACB5" } ] } ] }, { "uniprot_ac": "A0A8V1ACF6", "gene_name": "PIM1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACF6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ACF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACF6" } ] } ] }, { "uniprot_ac": "A0A8V1ACK0", "gene_name": "MAPKAPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACK0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ACK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACK0" } ] } ] }, { "uniprot_ac": "A0A8V1ACW2", "gene_name": "WNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACW2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ACW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACW2" } ] } ] }, { "uniprot_ac": "A0A8V1ADF0", "gene_name": "MAP2K2", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ADF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADF0" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V1ADF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADF0" } ] } ] }, { "uniprot_ac": "A0A8V1ADN9", "gene_name": "NLK", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ADN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADN9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V1ADN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADN9" } ] } ] }, { "uniprot_ac": "A0A8V1ADT4", "gene_name": "MKNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ADT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADT4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ADT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADT4" } ] } ] }, { "uniprot_ac": "A0A8V1AE45", "gene_name": "ERN1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AE45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE45" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AE45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE45" } ] } ] }, { "uniprot_ac": "A0A8V1AEH4", "gene_name": "STK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AEH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEH4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AEH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEH4" } ] } ] }, { "uniprot_ac": "A0A8V1AFS4", "gene_name": "STKLD1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AFS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFS4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AFS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFS4" } ] } ] }, { "uniprot_ac": "A0A8V1AG70", "gene_name": "LOC100857512", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AG70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AG70" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AG70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AG70" } ] } ] }, { "uniprot_ac": "A0A8V1AH12", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AH12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH12" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AH12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH12" } ] } ] }, { "uniprot_ac": "A0A8V1AHA8", "gene_name": "NEK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AHA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHA8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AHA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHA8" } ] } ] }, { "uniprot_ac": "A0A8V1AIY7", "gene_name": "AATK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AIY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIY7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AIY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIY7" } ] } ] }, { "uniprot_ac": "A0A8V1AJA4", "gene_name": "RPS6KB1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AJA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJA4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AJA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJA4" } ] } ] }, { "uniprot_ac": "A0A8V1AKW4", "gene_name": "MAP2K4", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AKW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKW4" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V1AKW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKW4" } ] } ] }, { "uniprot_ac": "A0A8V1AM12", "gene_name": "GSG2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AM12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM12" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AM12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM12" } ] } ] }, { "uniprot_ac": "A0A8V1AMK5", "gene_name": "PRKCA", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AMK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMK5" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V1AMK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMK5" } ] } ] }, { "uniprot_ac": "A0A8V1AMQ2", "gene_name": "CAMKK1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AMQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMQ2" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V1AMQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMQ2" } ] } ] }, { "uniprot_ac": "A0A8V1AP60", "gene_name": "KSR1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AP60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP60" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AP60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP60" } ] } ] }, { "uniprot_ac": "A0M8T9", "gene_name": "MET", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0M8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0M8T9" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0M8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0M8T9" } ] } ] }, { "uniprot_ac": "E1BQN6", "gene_name": "PRKCZ", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BQN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQN6" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1BQN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQN6" } ] } ] }, { "uniprot_ac": "E1BQV7", "gene_name": "SLK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BQV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQV7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BQV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQV7" } ] } ] }, { "uniprot_ac": "E1BUG0", "gene_name": "CDK12", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] } ] }, { "uniprot_ac": "E1BW33", "gene_name": "SMG1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BW33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BW33" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BW33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BW33" } ] } ] }, { "uniprot_ac": "E1BWA3", "gene_name": "PRKCI", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BWA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWA3" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1BWA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWA3" } ] } ] }, { "uniprot_ac": "E1BWT0", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BWT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWT0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BWT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWT0" } ] } ] }, { "uniprot_ac": "E1BX69", "gene_name": "EIF2AK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BX69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BX69" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BX69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BX69" } ] } ] }, { "uniprot_ac": "E1BY69", "gene_name": "PIM3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BY69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BY69" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BY69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BY69" } ] } ] }, { "uniprot_ac": "E1BYH2", "gene_name": "TAOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BYH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BYH2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BYH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BYH2" } ] } ] }, { "uniprot_ac": "E1C093", "gene_name": "PIK3CG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.154", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.154", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] } ] }, { "uniprot_ac": "E1C2I2", "gene_name": "MASTL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C2I2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C2I2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C2I2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C2I2" } ] } ] }, { "uniprot_ac": "E1C581", "gene_name": "TBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C581", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C581" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C581", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C581" } ] } ] }, { "uniprot_ac": "E1C6T4", "gene_name": "PRKD3", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C6T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C6T4" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1C6T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C6T4" } ] } ] }, { "uniprot_ac": "E1C764", "gene_name": "BMP2K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C764", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C764" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C764", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C764" } ] } ] }, { "uniprot_ac": "E1C848", "gene_name": "MAP3K8", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C848", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C848" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1C848", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C848" } ] } ] }, { "uniprot_ac": "F1NA68", "gene_name": "CDK3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NA68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NA68" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1NA68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NA68" } ] } ] }, { "uniprot_ac": "F1NB57", "gene_name": "PLK2", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NB57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NB57" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "F1NB57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NB57" } ] } ] }, { "uniprot_ac": "F1NBT0", "gene_name": "STK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NBT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NBT0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1NBT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NBT0" } ] } ] }, { "uniprot_ac": "F1NCL8", "gene_name": "FGFR4", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NCL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCL8" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1NCL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCL8" } ] } ] }, { "uniprot_ac": "F1NCX7", "gene_name": "PLK1", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NCX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCX7" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "F1NCX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCX7" } ] } ] }, { "uniprot_ac": "F1NCY7", "gene_name": "MAPKAPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NCY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCY7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1NCY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCY7" } ] } ] }, { "uniprot_ac": "F1NJH1", "gene_name": "PRKCH", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NJH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NJH1" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1NJH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NJH1" } ] } ] }, { "uniprot_ac": "F1NKW3", "gene_name": "MAP3K15", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NKW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NKW3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1NKW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NKW3" } ] } ] }, { "uniprot_ac": "F1NLR7", "gene_name": "CLK3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NLR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NLR7" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "F1NLR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NLR7" } ] } ] }, { "uniprot_ac": "F1NUX4", "gene_name": "MTOR", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NUX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NUX4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1NUX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NUX4" } ] } ] }, { "uniprot_ac": "F1NVF2", "gene_name": "MAP2K6", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NVF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NVF2" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "F1NVF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NVF2" } ] } ] }, { "uniprot_ac": "F1P011", "gene_name": "CAMK2A", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1P011", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P011" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "F1P011", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P011" } ] } ] }, { "uniprot_ac": "F1P356", "gene_name": "NUAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1P356", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P356" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1P356", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P356" } ] } ] }, { "uniprot_ac": "F1P4G3", "gene_name": "HIPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1P4G3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P4G3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1P4G3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P4G3" } ] } ] }, { "uniprot_ac": "P05625", "gene_name": "RAF1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P05625", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05625" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P05625", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05625" } ] } ] }, { "uniprot_ac": "P08642", "gene_name": "HRAS", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "P08642", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P08642" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "P08642", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P08642" } ] } ] }, { "uniprot_ac": "P10741", "gene_name": "MOS", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P10741", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P10741" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P10741", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P10741" } ] } ] }, { "uniprot_ac": "P13863", "gene_name": "CDK1", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P13863", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13863" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "P13863", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13863" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "P13863", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13863" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "P13863", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13863" } ] } ] }, { "uniprot_ac": "P18652", "gene_name": "RPS6KA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P18652", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P18652" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P18652", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P18652" } ] } ] }, { "uniprot_ac": "P21868", "gene_name": "CSNK2A1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P21868", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P21868" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P21868", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P21868" } ] } ] }, { "uniprot_ac": "P21869", 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{ "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1NLT8-1", "uniprot_ac": "F1NLT8", "uniprot_id": "F1NLT8_CHICK", "mass": { "chemical_mass": 22886.0, "monoisotopic_mass": 22886.0 }, "refseq": { "ac": "NP_001264293", "name": "rho GDP-dissociation inhibitor 2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264293" }, "gene_names": [ { "name": "ARHGDIB", "type": "recommended", "evidence": [ { "id": "F1NLT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NLT8" } ] }, { "name": "ARHGDIB", "type": "synonym", "evidence": [ { "id": "NP_001264293", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264293" } ] } ], "protein_names": [ { "name": "Rho GDP dissociation inhibitor (GDI) beta", "type": "synonym", "evidence": [ { "id": "NP_001264293", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264293" } ] }, { "name": "Rho GDP dissociation inhibitor beta", "type": "synonym", "evidence": [ { "id": "F1NLT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NLT8/entry#names_and_taxonomy" } ] }, { "name": "rho GDP-dissociation inhibitor 2", "type": "synonym", "evidence": [ { "id": "NP_001264293", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264293" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: HAEK01007393.1, HAEK01203098.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000012.1. On Apr 5, 2013 this sequence version replaced XP_416182.1. Sequence Note: This RefSeq record was created from transcript data from different strains because no single transcript from the same strain was available for the full length of the gene. The extent of this transcript is supported by transcript alignments and orthologous data.", "evidence": [ { "database": "RefSeq", "id": "NP_001264293", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264293" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NLT8", "url": "https://www.uniprot.org/uniprotkb/F1NLT8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ARHGDIB", "url": "https://www.uniprot.org/uniprotkb/F1NLT8", "locus": { "chromosome": "1", "start_pos": 48036687, "end_pos": 48027526, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012059", "url": "https://www.ensembl.org/id/ENSGALG00010012059" } ] } } ], "crossref": [ { "id": "F1NLT8", "url": "https://alphafold.ebi.ac.uk/entry/F1NLT8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000011738", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000011738", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "417941", "url": "https://www.ncbi.nlm.nih.gov/gene/417941", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000406", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000406", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014756", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014756", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024792", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024792", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:417941", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417941", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YKPTAAK", "url": "https://omabrowser.org/oma/group/YKPTAAK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YKQ8", "url": "https://www.orthodb.org/?gene=A0A8V0YKQ8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NLT8", "url": "https://www.orthodb.org/?gene=F1NLT8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10980", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10980", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10980:SF15", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10980:SF15", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02115", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02115", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-8980692", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8980692", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9013148", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013148", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9013149", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013149", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9013407", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013407", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9013408", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013408", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9013423", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013423", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001264293", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264293", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YKQ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKQ8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YKQ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKQ8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NLT8", "url": "https://www.uniprot.org/uniprotkb/F1NLT8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NLT8-1", "url": "https://www.uniprot.org/uniprotkb/F1NLT8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTEKTQEPHVEEDDDELDGKLNYKPPPQKTLQELQELDKDDESLTKYKKSLLGDGPVVADPTAPNVVVTRLTLVCDSAPGPITMDLTGDLEALKKETFVLKEGVEYRVKIHFKVNRDIVSGLKYVQHTYRTGVKVDKATFMVGSYGPRPEEYEFLTPIEEAPKGMLARGTYHNKSFFTDDDKHDHLTWEWNLSIKKEWTE", "length": 200, "header": "tr|F1NLT8-1|F1NLT8_CHICK Isoform 1 of Rho GDP dissociation inhibitor beta OS=Gallus gallus OX=9031 GN=ARHGDIB PE=1 SV=2 CANONICAL=F1NLT8-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YKQ8-1", "url": "https://www.uniprot.org/uniprotkb/F1NLT8/entry#A0A8V0YKQ8-1", "sequence": { "sequence": "MTEKTQEPHVEEDDDELDGKLNYKPPPQKTLQELQELDKDDESLTKYKKSLLGDGPVVADPTAPNVVVTRLTLVCDSAPGPITMDLTGDLEALKKETFVLKEGVEYRVKIHFKVNRDIVSGLKYVQHTYRTGVKVDKATFMVGSYGPRPEEYEFLTPIEEAPKGMLARGTYHNKSFFTDDAQACRWPLLLLLIH", "length": 194, "header": "tr|A0A8V0YKQ8-1|A0A8V0YKQ8_CHICK Computationally mapped isoform of Rho GDP dissociation inhibitor beta OS=Gallus gallus OX=9031 GN=ARHGDIB PE=1 SV=1 CANONICAL=F1NLT8-1" }, "locus": { "chromosome": "1", "start_pos": 48036272, "end_pos": 48031703, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028883.1", "url": "https://www.ensembl.org/id/ENSGALT00010028883.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016642.1", "url": "https://www.ensembl.org/id/ENSGALP00010016642.1" } ] } }, { "isoform_ac": "F1NLT8-1", "url": "https://www.uniprot.org/uniprotkb/F1NLT8/entry#F1NLT8-1", "sequence": { "sequence": "MTEKTQEPHVEEDDDELDGKLNYKPPPQKTLQELQELDKDDESLTKYKKSLLGDGPVVADPTAPNVVVTRLTLVCDSAPGPITMDLTGDLEALKKETFVLKEGVEYRVKIHFKVNRDIVSGLKYVQHTYRTGVKVDKATFMVGSYGPRPEEYEFLTPIEEAPKGMLARGTYHNKSFFTDDDKHDHLTWEWNLSIKKEWTE", "length": 200, "header": "tr|F1NLT8-1|F1NLT8_CHICK Isoform 1 of Rho GDP dissociation inhibitor beta OS=Gallus gallus OX=9031 GN=ARHGDIB PE=1 SV=2 CANONICAL=F1NLT8-1" }, "locus": { "chromosome": "1", "start_pos": 48036067, "end_pos": 48031703, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028886.1", "url": "https://www.ensembl.org/id/ENSGALT00010028886.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016645.1", "url": "https://www.ensembl.org/id/ENSGALP00010016645.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:417941", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417941", "resource": "KEGG Pathway" }, { "id": "R-GGA-8980692", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8980692", "resource": "Reactome", "description": "RHOA GTPase cycle" }, { "id": "R-GGA-9013148", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013148", "resource": "Reactome", "description": "CDC42 GTPase cycle" }, { "id": "R-GGA-9013149", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013149", "resource": "Reactome", "description": "RAC1 GTPase cycle" }, { "id": "R-GGA-9013407", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013407", "resource": "Reactome", "description": "RHOH GTPase cycle" }, { "id": "R-GGA-9013408", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013408", "resource": "Reactome", "description": "RHOG GTPase cycle" }, { "id": "R-GGA-9013423", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013423", "resource": "Reactome", "description": "RAC3 GTPase cycle" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A4X1V4G4-1", "protein_name": "Rho GDP dissociation inhibitor beta", "gene_name": "ARHGDIB", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTEKDPEPHLEEDDDELDGKLNYKPPPQKSLKELQEMDKDDESLTKYKKTLLGDGPVVADPSAPNVTVTRLTLVCESAPGPITMDLTGDLEALKKETFVLKEGVEYRVKIHFKVNKDIVSGLKYVQHTYRTGVKVDKATFMVGSYGPRPEEYEFLTPTEEAPKGMLARGTYHNKSFFTDDDKHDHLTWEWNLSIKKDWTE", "length": 200 }, "evidence": [ { "id": "F1NLT8", "url": "https://omabrowser.org/oma/group/F1NLT8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8I5ZXI2-1", "protein_name": "Rho GDP dissociation inhibitor beta", "gene_name": "Arhgdib", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MIRKVLTRLLGQKGEVSPGKGDKLKEVGESILLPECSREGTIKMTEKDEQPQLEEGEDELDSKLNYKPPPQKSLKELQEMDKDDESLTKYKKTLLGDVPVVADPTVPNVTVTRLSLVCDSAPGPITMDLTGDLKALKKDTFVLKEGIEYRVKINFKVNKDIVSGLKYVQQTYRNGMKVDKATFMVGSYGPRPEEYEFLTPVEEAPKGMLARGTYHNKSFFTDDDKQDHLTWEWNLAIKKDWTD", "length": 243 }, "evidence": [ { "id": "F1NLT8", "url": "https://omabrowser.org/oma/group/F1NLT8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O65371-1", "protein_name": "Immunoglobulin E-set superfamily protein", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MVLNDEEMKAGESSEEPKGQGLSRKNSHSSMCPTDDDEEEEDKKLELGPMIALKEQLEKDKDDESLRRWKEQLLGSVDLEEVGETPDPLVKILTLTIRSPDREDMVLTIPENGKPASKGPWFTLKEGSKYTLIFTFRVTNNIVSGLQYSNTVWKTGIKVYSRKEMLGTFSPQAEPYTHVMFEETAPSGLLVRGSYSVKSKFVDDDNQCYLENNYTFDIRKNWL", "length": 223 }, "evidence": [ { "id": "F1NLT8", "url": "https://omabrowser.org/oma/group/F1NLT8/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "P52566-1", "protein_name": "Rho GDP-dissociation inhibitor 2", "gene_name": "ARHGDIB", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTEKAPEPHVEEDDDDELDSKLNYKPPPQKSLKELQEMDKDDESLIKYKKTLLGDGPVVTDPKAPNVVVTRLTLVCESAPGPITMDLTGDLEALKKETIVLKEGSEYRVKIHFKVNRDIVSGLKYVQHTYRTGVKVDKATFMVGSYGPRPEEYEFLTPVEEAPKGMLARGTYHNKSFFTDDDKQDHLSWEWNLSIKKEWTE", "length": 201 }, "evidence": [ { "id": "F1NLT8", "url": "https://omabrowser.org/oma/group/F1NLT8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q12434-1", "protein_name": "Rho GDP-dissociation inhibitor", "gene_name": "RDI1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MAEESTDFSQFEEERNNDQYKVSAKKTVDEYKNLDAEDESLAKWKESLGLSSDVLPLEFPGDKRKVVVQKIQLLVNTEPNPITFDLTNEKTIKELASKRYKIKENSIYKLKIVFKVQHEIITGLRYVQYIKKAGIAVDKIDDHLGSYAPNTKTKPFYEVELPESEAPSGFLARGNYSAVSKFIDDDKTNHLTLNWGVEIVKK", "length": 202 }, "evidence": [ { "id": "F1NLT8", "url": "https://omabrowser.org/oma/group/F1NLT8/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q61599-1", "protein_name": "Rho GDP-dissociation inhibitor 2", "gene_name": "Arhgdib", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTEKDAQPQLEEADDDLDSKLNYKPPPQKSLKELQEMDKDDESLTKYKKTLLGDVPVVADPTVPNVTVTRLSLVCDSAPGPITMDLTGDLEALKKDTFVLKEGIEYRVKINFKVNKDIVSGLKYVQHTYRTGMRVDKATFMVGSYGPRPEEYEFLTPVEEAPKGMLARGTYHNKSFFTDDDKQDHLTWEWNLAIKKDWTE", "length": 200 }, "evidence": [ { "id": "F1NLT8", "url": "https://omabrowser.org/oma/group/F1NLT8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q95UQ1-1", "protein_name": "Putative rho GDP-dissociation inhibitor 1", "gene_name": "rdiA", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSDNHEEESNVPAYVPGKHVSVDQLKQQDAEDEALKRYKESLLGTGVHAPKDDPRKLVIKEMKIQIEGRPDTIYPLDTKELIKEMKTKPFVLKESCHYKITLTFNIQHDIVSGLKQTNTVYRKGIKVSTEKHMLGSFAPQALAHSVTNPRHGWEEAPSGMLARGSYTAKVVFTDDDNEEHLSVEYAFSIKSDWKSDD", "length": 197 }, "evidence": [ { "id": "F1NLT8", "url": "https://omabrowser.org/oma/group/F1NLT8/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "Rho GDP-dissociation inhibitor activity", "id": "GO:0005094", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005094", "evidence": [ { "database": "UniProtKB", "id": "F1NLT8", "url": "https://www.uniprot.org/uniprotkb/F1NLT8" } ], "pmid": "" }, { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "F1NLT8", "url": "https://www.uniprot.org/uniprotkb/F1NLT8" } ], "pmid": "" }, { "name": "GTPase activity", "id": "GO:0003924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003924", "evidence": [ { "database": "UniProtKB", "id": "F1NLT8", "url": "https://www.uniprot.org/uniprotkb/F1NLT8" } ], "pmid": "" }, { "name": "small GTPase binding", "id": "GO:0031267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031267", "evidence": [ { "database": "UniProtKB", "id": "F1NLT8", "url": "https://www.uniprot.org/uniprotkb/F1NLT8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1NLT8", "url": "https://www.uniprot.org/uniprotkb/F1NLT8" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F1NLT8", "url": "https://www.uniprot.org/uniprotkb/F1NLT8" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "F1NLT8", "url": "https://www.uniprot.org/uniprotkb/F1NLT8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "Rho protein signal transduction", "id": "GO:0007266", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007266", "evidence": [ { "database": "UniProtKB", "id": "F1NLT8", "url": "https://www.uniprot.org/uniprotkb/F1NLT8" } ], "pmid": "" }, { "name": "regulation of Rho protein signal transduction", "id": "GO:0035023", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035023", "evidence": [ { "database": "UniProtKB", "id": "F1NLT8", "url": "https://www.uniprot.org/uniprotkb/F1NLT8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 173, "end_pos": 175, "annotation": "n_glycosylation_sequon" }, { "start_pos": 191, "end_pos": 193, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1NLT8-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 200, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1NLT8-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1NLT8" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 173, "end_pos": 175 }, { "start_pos": 191, "end_pos": 193 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1NYF5-1", "uniprot_ac": "F1NYF5", "uniprot_id": "F1NYF5_CHICK", "mass": { "chemical_mass": 55704.0, "monoisotopic_mass": 55704.0 }, "refseq": { "ac": "NP_001025932", "name": "periodic tryptophan protein 1 homolog", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025932" }, "gene_names": [ { "name": "PWP1", "type": "recommended", "evidence": [ { "id": "F1NYF5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NYF5" } ] }, { "name": "PWP1", "type": "synonym", "evidence": [ { "id": "NP_001025932", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025932" } ] } ], "protein_names": [ { "name": "Periodic tryptophan protein 1 homolog", "type": "recommended", "evidence": [ { "id": "F1NYF5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NYF5/entry#names_and_taxonomy" } ] }, { "name": "periodic tryptophan protein 1 homolog", "type": "synonym", "evidence": [ { "id": "NP_001025932", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025932" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ720939.1, SRR13267656.6582.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA103992290, SAMEA103992323 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000012.1. On Aug 10, 2010 this sequence version replaced NP_001025932.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001025932", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025932" } ] }, { "annotation": "Chromatin-associated factor that regulates transcription. Regulates Pol I-mediated rRNA biogenesis and, probably, Pol III-mediated transcription. Regulates the epigenetic status of rDNA.", "evidence": [ { "database": "UniProtKB", "id": "F1NYF5", "url": "https://www.uniprot.org/uniprotkb/F1NYF5#function" }, { "database": "UniProtKB", "id": "ARBA00059325", "url": "https://www.uniprot.org/uniprotkb/ARBA00059325#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NYF5", "url": "https://www.uniprot.org/uniprotkb/F1NYF5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PWP1", "url": "https://www.uniprot.org/uniprotkb/F1NYF5", "locus": { "chromosome": "1", "start_pos": 53388607, "end_pos": 53403927, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010015613", "url": "https://www.ensembl.org/id/ENSGALG00010015613" } ] } } ], "crossref": [ { "id": "F1NYF5", "url": "https://alphafold.ebi.ac.uk/entry/F1NYF5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000012631", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000012631", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "418066", "url": "https://www.ncbi.nlm.nih.gov/gene/418066", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001680", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001680", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019775", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019775", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020472", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020472", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036322", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036322", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044285", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044285", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:418066", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418066", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CFVPRGV", "url": "https://omabrowser.org/oma/group/CFVPRGV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YLA1", "url": "https://www.orthodb.org/?gene=A0A8V0YLA1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NYF5", "url": "https://www.orthodb.org/?gene=F1NYF5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14091", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14091", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14091:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14091:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00400", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00400", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001025932", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025932", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YLA1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLA1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLA1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLA1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NYF5", "url": "https://www.uniprot.org/uniprotkb/F1NYF5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NYF5-1", "url": "https://www.uniprot.org/uniprotkb/F1NYF5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSCPVTCAAWVRRGVAKETPDKVQLSREELRRLVGEARGRLREGSDGSDEEDQGQAADGMEVAMADRAESPPDNEEQEEGAEKLTDDELAEYDLDKYDEEEGGGDTKLGETLAGLAVYGSNDQDPYITLKNTDQYEQEDFLIKPNDNLVLCGRVDKDYCSLEVHVYNHEEDSFYVHHDIILPAYPLSLEWLNFDPNPEESSGNYVAVGNMTPVIDIWDLDIVDCLEPVFSLGSKKEKKKKKKGKKGLPQEGTVEGHADAVLDLSWNKQSRNVLASASADSTVILWDMSVGKPAASLTLHTDKVQTLQFHPFETQTLISGSYDKSAVLYDCRSPQDNHRIWRFSGQVERVTWNHFSPCNFLASTEDGFVYCLDARSDKPLFTLKAHDEEVSGLQLSSQVKGCLVTSSADKYVKIWDILGGKPSLIHSRDMKMGVLFCAACCPDFPFVFAFGGEREGLRVWDISSISAVNEVFGNRERLVLAGANSVACSSLAGSSSNSSETAMES", "length": 504, "header": "tr|F1NYF5-1|F1NYF5_CHICK Isoform 1 of Periodic tryptophan protein 1 homolog OS=Gallus gallus OX=9031 GN=PWP1 PE=1 SV=2 CANONICAL=F1NYF5-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YLA1-1", "url": "https://www.uniprot.org/uniprotkb/F1NYF5/entry#A0A8V0YLA1-1", "sequence": { "sequence": "MSCPVTCAAWVRRGVAKETPDKVQLSREELRRLVGEARGRLREGSDGSDEEDQGQAADGMEVAMADRAESPPDNEEQEEGAEKLTDDELAEYDLDKYDEEEGGGDTKLGETLAGLAVYGSNDQDPYITLKNTDQYEQEDFLIKPNDNLVLCGRVDKDYCSLEVHVYNHEEDSFYVHHDIILPAYPLSLEWLNFDPNPEESSGLQLSSQVKGCLVTSSADKYVKIWDILGGKPSLIHSRDMKMGVLFCAACCPDFPFVFAFGGEREGLRVWDISSISAVNEVFGNRERLVLAGANSVACSSLAGSSSNSSETAMES", "length": 315, "header": "tr|A0A8V0YLA1-1|A0A8V0YLA1_CHICK Computationally mapped isoform of PWP1 homolog, endonuclein OS=Gallus gallus OX=9031 GN=PWP1 PE=1 SV=1 CANONICAL=F1NYF5-1" }, "locus": { "chromosome": "1", "start_pos": 53403884, "end_pos": 53390862, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010037570.1", "url": "https://www.ensembl.org/id/ENSGALT00010037570.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021727.1", "url": "https://www.ensembl.org/id/ENSGALP00010021727.1" } ] } }, { "isoform_ac": "F1NYF5-1", "url": "https://www.uniprot.org/uniprotkb/F1NYF5/entry#F1NYF5-1", "sequence": { "sequence": "MSCPVTCAAWVRRGVAKETPDKVQLSREELRRLVGEARGRLREGSDGSDEEDQGQAADGMEVAMADRAESPPDNEEQEEGAEKLTDDELAEYDLDKYDEEEGGGDTKLGETLAGLAVYGSNDQDPYITLKNTDQYEQEDFLIKPNDNLVLCGRVDKDYCSLEVHVYNHEEDSFYVHHDIILPAYPLSLEWLNFDPNPEESSGNYVAVGNMTPVIDIWDLDIVDCLEPVFSLGSKKEKKKKKKGKKGLPQEGTVEGHADAVLDLSWNKQSRNVLASASADSTVILWDMSVGKPAASLTLHTDKVQTLQFHPFETQTLISGSYDKSAVLYDCRSPQDNHRIWRFSGQVERVTWNHFSPCNFLASTEDGFVYCLDARSDKPLFTLKAHDEEVSGLQLSSQVKGCLVTSSADKYVKIWDILGGKPSLIHSRDMKMGVLFCAACCPDFPFVFAFGGEREGLRVWDISSISAVNEVFGNRERLVLAGANSVACSSLAGSSSNSSETAMES", "length": 504, "header": "tr|F1NYF5-1|F1NYF5_CHICK Isoform 1 of Periodic tryptophan protein 1 homolog OS=Gallus gallus OX=9031 GN=PWP1 PE=1 SV=2 CANONICAL=F1NYF5-1" }, "locus": { "chromosome": "1", "start_pos": 53403884, "end_pos": 53390862, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010037586.1", "url": "https://www.ensembl.org/id/ENSGALT00010037586.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021734.1", "url": "https://www.ensembl.org/id/ENSGALP00010021734.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:418066", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418066", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0ABK0LFY1-1", "protein_name": "Periodic tryptophan protein 1 homolog", "gene_name": "Pwp1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MNRSRQVTCVAWVRRGVAKETPDKVELSKEEVKRLIAEAKEKLQEEGGSEEEEVGSPSEDGMQRARVQARPTEPLEDGDPQDDRTLDDDELAEYDLDNYDQEDNPDAETIGESLLGLTVYGSNDQDPYVTLKDTEQYEHEDFLIKPTDNLIVCGRAEQEQCNLEVHVYNQEEESFYVHHDILLSAYPLSVEWLNFDPSPDAATGNYIAVGNMTPVIEVWDLDIVDSLEPVFTLGSKLSKKKKKKGKKSSSAEGHTDAVLDLSWNKTVRNVLASASADSTVILWDLSVGKPAARLTAHTDKVQTLQFHPFEAQTLISGSYDKSVALYDCRDPSQNHRLWRFSGQIERVTWNHFSPCHFLASTDDGFVYNLDARSDKPIFTLNAHNDEISGLDLSSQIKGCLVTASADKFVKIWDILGERPSLIHSRDMKMGVLFCSSCCPDLPFVYAFGGQKEGLRVWDISTVSSVNEAFGRRERLAIGSTKDPWDPLHLAGEDSARKTTGKA", "length": 502 }, "evidence": [ { "id": "F1NYF5", "url": "https://omabrowser.org/oma/group/F1NYF5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A1Z8D0-1", "protein_name": "Periodic tryptophan protein 1 homolog", "gene_name": "nclb", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MAEEGPPEPSIDFVPALCFVPRGVAKDRPDKIVLTQAELARIIGDTQQELDEESDDDAEEGENAEEDQNDMDVDDHADANSENRDPQDEFQFQEYDNEANANVTSLANIVDAGEQIPDEDEDSEAEDEVIKPSDNLILVGHVQDDAASMEVWVFNQEEEALYTHHDFLLPSFPLCIEWMNHDAGSEKAGNMCAIGCMDPIITVWDLDIQDAIEPTFKLGSKGSRKQNKEQYGHKDAVLDLSWNTNFEHILASGSVDQTVILWDMDEGQPHTTITAFGKQIQSLEFHPQEAQSILTGCADGYVRLFDCRDAEGVNSSSIEWKVDGEVEKVLWHPTQTDYFIVGTNDGTLHYADKRSPGQLLWSVKAHNEEISGVCFNNQKPNLLTSTSTEGTLKVWNFDGTEAKHVYEHEFNMGRLQCMRQCPEDPYTLAFGGEKPPRCAIFNIKNSIAVRRTFGIPDAE", "length": 459 }, "evidence": [ { "id": "F1NYF5", "url": "https://omabrowser.org/oma/group/F1NYF5/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "F4JSC0-1", "protein_name": "Transducin/WD40 repeat-like superfamily protein", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MITAVSWIPKGNLKAVPDVAEPPSKEELKELIESGAFARNVEGSNEDEEEEIEEDGEEISEVDHAKAVAEALGKSSKSKAVSSSMEVDEVSQGLKELDMDNYDEEDDEIELFSSGMGDLYYPSNEMDPYLKDVDDEDDEEDIDDTTVKPTDSVIICARNEDDVSHLEVYLYEESSGSPNMYVHHHIIIPEFPLCTAWLDCPLKGGEKGNFVAIGSKDTPTIEIWDLDVRDEVLPCIQLGGIEEMIVSKKKKSKKQKPVCASNSSISSSSMASSHTESVLGLAWNKEFRNILASASADKKVKVWDVATGTCKITMEHHTKEVQAVAWNHYAPEVLLSGSFDQTVVMKDGRQPSHSGFKWSVMSDVESLAWDPHCEHSFVVSLEDGTVKGFDIRAAQSGSDSDLNPTYTIQAHAQDRGVSSISYNISTPNLLATGSMDKSVKLWDLSNNEPSCIATHQPNAGAVFSISFAVDNPFLLAIGGSKGELHVWDTLLDANVARKYGSNRS", "length": 504 }, "evidence": [ { "id": "F1NYF5", "url": "https://omabrowser.org/oma/group/F1NYF5/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "P21304-1", "protein_name": "Periodic tryptophan protein 1", "gene_name": "PWP1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MISATNWVPRGFSSEFPEKYVLDDEEVERINQLAQLNLDDAKATLEEAEGESGVEDDAATGSSNKLKDQLDIDDDLKEYNLEEYDDEEIADNEGGKDVSMFPGLSNDSDVKFHEGEKGEDPYISLPNQEDSQEEKQELQVYPSDNLVLAARTEDDVSYLDIYVYDDGAGFHSSDIPVEEGDEADPDVARGLVRDPALYVHHDLMLPAFPLCVEWLDYKVGSNSEEAANYAAIGTFDPQIEIWNLDCVDKAFPDMILGEPLDNSMVSLKSKKKKKKSKTGHITTHHTDAVLSMAHNKYFRSVLASTSADHTVKLWDLNSGNAARSLASIHSNKNVSSSEWHMLNGSILLTGGYDSRVALTDVRISDESQMSKYWSAMAGEEIETVTFASENIILCGTDSGNVYSFDIRNNENRKPVWTLKAHDAGISTLCSNKFIPGMMSTGAMGEKTVKLWKFPLDDATNTKGPSMVLSRDFDVGNVLTSSFAPDIEVAGTMVIGGVNKVLKLWDVFTNRSVRKSFKSELENVQARAKEEAQKIGKSSRIARKYTSNDNPDTVITIDDQGEDEEEREGGDEHDDMA", "length": 576 }, "evidence": [ { "id": "F1NYF5", "url": "https://omabrowser.org/oma/group/F1NYF5/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q13610-1", "protein_name": "Periodic tryptophan protein 1 homolog", "gene_name": "PWP1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNRSRQVTCVAWVRCGVAKETPDKVELSKEEVKRLIAEAKEKLQEEGGGSDEEETGSPSEDGMQSARTQARPREPLEDGDPEDDRTLDDDELAEYDLDKYDEEGDPDAETLGESLLGLTVYGSNDQDPYVTLKDTEQYEREDFLIKPSDNLIVCGRAEQDQCNLEVHVYNQEEDSFYVHHDILLSAYPLSVEWLNFDPSPDDSTGNYIAVGNMTPVIEVWDLDIVDSLEPVFTLGSKLSKKKKKKGKKSSSAEGHTDAVLDLSWNKLIRNVLASASADNTVILWDMSLGKPAASLAVHTDKVQTLQFHPFEAQTLISGSYDKSVALYDCRSPDESHRMWRFSGQIERVTWNHFSPCHFLASTDDGFVYNLDARSDKPIFTLNAHNDEISGLDLSSQIKGCLVTASADKYVKIWDILGDRPSLVHSRDMKMGVLFCSSCCPDLPFIYAFGGQKEGLRVWDISTVSSVNEAFGRRERLVLGSARNSSISGPFGSRSSDTPMES", "length": 501 }, "evidence": [ { "id": "F1NYF5", "url": "https://omabrowser.org/oma/group/F1NYF5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q2HJ56-1", "protein_name": "Periodic tryptophan protein 1 homolog", "gene_name": "PWP1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MNRSRQVTCVAWVRCGVAKETPDKVELSKEEVKRLIAEAKEKLQEEGGSDEQETGNPSEDGMQSARTQARPREPLEDGDPEDDRTLDDDELAEYDLDKYDEEGDPDAETLGESLLGLTVYGSNDQDPYVTLKDTEQYEREDFLIKPSDNLIVCGRAEQDQCNLEVHVYNQEEDSFYVHHDILLSAYPLSVEWLNFDPSPDDSTGNYIAVGNMTPVIEVWDLDIVDSLEPVFTLGSKLSKKKKKKGKKNSSADGHTDAVLDLSWNKLVRNVLASASADNTVILWDMSLGKPAASLAVHTDKVQTLQFHPFEAQTLISGSYDKSVALYDCRSPEESHRMWRFSGQIERVTWNHFSPCHFLASTDDGFVYNLDARSDKPIFTLNAHNDEISGLDLSSQIKGCLVTASADKYVKIWDILGDRPSLVHSRDMKMGVLFCSSCCPDLPFIYAFGGQKEGLRVWDISTVSSVNEAFGRRERLVLGNARTSSISGPFGNRSSETPMES", "length": 500 }, "evidence": [ { "id": "F1NYF5", "url": "https://omabrowser.org/oma/group/F1NYF5/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q869X0-1", "protein_name": "WD40 repeat-containing protein", "gene_name": "pwp1", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MISSIQWVPRGASNPFPKKFDPNGEDMEELNEEEIKAMQEEEEEDRIIEKKFEKGVPSVMNDKEKDFYKRYNFDDYDSDEGEQDEEERDENDHSRKTEEVGLKFINRAMKGLMFYKDTDSDPYLTNKEEEDIEDIEDVIIRPTDSILVSAIVTGEDDYSHLDIMVYEEECDNLYVHHDIILSSYPLALAWMDQNPINPQEKGSFMAVGTFEPSIEIWDLDVVDNLIPTVILGGKEEDSADPMKKPSAKKRGGKHNKFKEGSHRDGVMSLSWNSHQRNVLASGSSDNTVKVWDITTQQCLNTFTHHKDKVSCLHWNSHEKTALLIGSHDKHVSILDVRAPDSAYKWSVKGEVESLSWNPHNPKEFIVGTDDGRLLCYDATLGTAAAPVWSVQASQKGSVSCFSYCPGQVGFFATGSSDHTVKLWNLETSSNKPTLIESKNLGQEIFTLSFFENSPFLLAVGSETQRPNVIDTKRFISVQNSFGIARPENSKEPVFITNNKNKNNTEEEEEEIEEDTDSDHNDDEIEEEQEEEEQEKEITPPPKQTKKLNNTKNNKKDVKNRKKVGDSDEE", "length": 569 }, "evidence": [ { "id": "F1NYF5", "url": "https://omabrowser.org/oma/group/F1NYF5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q99LL5-1", "protein_name": "Periodic tryptophan protein 1 homolog", "gene_name": "Pwp1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNRSRQVTCVAWVRRGVAKETPDKVELSKEEVNRLIAEAKGKLQEEGGSEEEEAGNPSEDGMQSGPTQAPPRESLEDGDPQDDRTLDDDELAGYDLDNYDEEDNPDAETIGESLLGLTVYGSNDQDPYVTLKDTEQYEHEDFLIKPTDNLIVCGRAEQEQCNLEVHVYNQEEESFYVHHDILLSAYPLSVEWLNFDPSPDASTGNYIAVGNMTPVIEVWDLDIVDSLEPVFTLGSKLSKKKKKKGKKSSSAEGHTDAVLDLSWNKTVRNVLASASADSTVVLWDLSVGKSVARLTAHTDKVQTLQFHPFEAQTLISGSYDKSVALYDCRDPSQNHRQWRFSGQIERVTWNHFSPCHFLASTDDGFVYNLDARSDKPIFTLNAHNDEISGLDLSSQIKGCLVTASADKFVKIWDILGDRPSLIHSRDMKMGVLFCSSCCPDLPFVYAFGGQKEGLRVWDISTVSSVNEAFGRRERLVIGGTKGLSVSGPCGSRSPQQTPMES", "length": 501 }, "evidence": [ { "id": "F1NYF5", "url": "https://omabrowser.org/oma/group/F1NYF5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "rRNA processing", "id": "GO:0006364", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006364", "evidence": [ { "database": "UniProtKB", "id": "F1NYF5", "url": "https://www.uniprot.org/uniprotkb/F1NYF5" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "F1NYF5", "url": "https://www.uniprot.org/uniprotkb/F1NYF5" } ], "pmid": "" }, { "name": "positive regulation of transcription of nucleolar large rRNA by RNA polymerase I", "id": "GO:1901838", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901838", "evidence": [ { "database": "UniProtKB", "id": "F1NYF5", "url": "https://www.uniprot.org/uniprotkb/F1NYF5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1NYF5", "url": "https://www.uniprot.org/uniprotkb/F1NYF5" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "F1NYF5", "url": "https://www.uniprot.org/uniprotkb/F1NYF5" } ], "pmid": "" }, { "name": "chromosome", "id": "GO:0005694", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005694", "evidence": [ { "database": "UniProtKB", "id": "F1NYF5", "url": "https://www.uniprot.org/uniprotkb/F1NYF5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "histone H4K20me3 reader activity", "id": "GO:1990889", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990889", "evidence": [ { "database": "UniProtKB", "id": "F1NYF5", "url": "https://www.uniprot.org/uniprotkb/F1NYF5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 209, "end_pos": 211, "annotation": "n_glycosylation_sequon" }, { "start_pos": 496, "end_pos": 498, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1NYF5-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 504, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1NYF5-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1NYF5" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 209, "end_pos": 211 }, { "start_pos": 496, "end_pos": 498 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1NJ66-1", "uniprot_ac": "F1NJ66", "uniprot_id": "F1NJ66_CHICK", "mass": { "chemical_mass": 314909.0, "monoisotopic_mass": 314909.0 }, "refseq": {}, "gene_names": [ { "name": "NIPBL", "type": "recommended", "evidence": [ { "id": "F1NJ66", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NJ66" } ] } ], "protein_names": [ { "name": "Nipped-B protein", "type": "recommended", "evidence": [ { "id": "F1NJ66", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NJ66/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NJ66", "url": "https://www.uniprot.org/uniprotkb/F1NJ66" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "NIPBL", "url": "https://www.uniprot.org/uniprotkb/F1NJ66", "locus": {} } ], "crossref": [ { "id": "ENSGALG00000003605", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000003605", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd23958", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd23958", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "427439", "url": "https://www.ncbi.nlm.nih.gov/gene/427439", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024986", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024986", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR026003", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026003", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033031", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033031", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "KQNENRM", "url": "https://omabrowser.org/oma/group/KQNENRM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PVC0", "url": "https://www.orthodb.org/?gene=A0A1D5PVC0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YFB3", "url": "https://www.orthodb.org/?gene=A0A8V0YFB3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YNF6", "url": "https://www.orthodb.org/?gene=A0A8V0YNF6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NJ66", "url": "https://www.orthodb.org/?gene=F1NJ66", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21704", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21704", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21704:SF18", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21704:SF18", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF12765", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12765", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12830", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12830", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:F1NJ66", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:F1NJ66", "database": "PRO", "categories": [ "Protein" ] }, { "id": "R-GGA-2470946", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2470946", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A1D5PVC0", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PVC0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PVC0-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PVC0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YFB3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFB3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YFB3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFB3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YNF6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNF6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YNF6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNF6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NJ66", "url": "https://www.uniprot.org/uniprotkb/F1NJ66", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NJ66-1", "url": "https://www.uniprot.org/uniprotkb/F1NJ66-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNGDMPHVPITTLAGIASLTDLLNQLPLPSPLPATTTKSLLFNGRIAEEVNCLLACRDENLVSQLIHSLNQVSTDHIELKDNLGSDDPEGDTPVLLQAILARNPNVFREKSMQNRYGVQSGMMIPQFNISQNSMRGSPASSNYQQTTISHSPSSRFVPPQTSSGNRFLAQQNSPVPSPYAPQSPAGYMPYSHPPSYTPHPQLQQACPIVTAGMRNLHENKVSSQLSGNSANHHADNSRHGSNEDYLQMVHRLSSDDGDPSIRNAASFSLRSPQSVCSPAGSDGTPKGSRPPLILQSQPPPYSSPRDVPPDILLDSPERKQKKQKKMKLGKDEKDQTEKAAMYDIISSPSKDSTKLTLRLSRVRSSDLDQQDDMLSGLENSSVSEGDIPFNVQYPGQTSKTPVTPQDVNRPLNAAQCLPQHEQTAFLQAQQVPVLQQNTSVAAKQPQTPVVQTQQQVSQQGTITSYDEVELDALAEIERIERESAIERERFSKEVQDKDKPLKKRKQENKPQEAGGAAGGNRPASQESGSAGNGARPALMVSIDLQQAGRADSQATITQEFEAIKKPEEIKQYNDGFVCIPQEETVGVLKLKPENHPEIFRKKSDFEVQKTDIQQNENRQMEFQQNESRRLESKYNDNKQVEAKYDIKHDSRQMEMKQNENRQAESKQNESRQMEMKQNEGKQNNGKQEIRQRPETPKQKSEGRPETPKQKSEGRPETPKHRHDNRRDSSKPLSEKKIELSRHKPDVKSDTSKVKSDSRSDPVKQRPDGRSVSDTQRRDHDSLKQRSEDRESERYKGDPSKIRRTEFLRSSNRNEHDSKYGIKSDGSKPEKFERKHRHDSGESRERFSSGDQKSDQKSRPDSPRVKQDGKGDSSKSRPDKPGFRSPNSKDERRTDSSKSKVESNKAHPDNKAEFPSYLLGARSGALKHFVIPKIKRDKDGNVTQESRKTELKGEQKDKVEKIGLVEDLNKGAKPVVVLQKLSLDDVQKFIKDREDKSRGSCFKPNKNKSSKSNKGSIDQSVLKELPPELLAEIESTMPLCERVKMNKRKRSTVNEKPKYAEISSDEDNDSEEAFESSRKRHKKDRDEAWEYEEHDRRSSGDHRRSGHYHEGRRTSGSGRYRNRSPDDSDLDDYSPPPSLSEVARKMKKKEKQKKRRAYEPKLTPEEMMDSSTFKRFIASIENILENLEDMDFTTLGDDDEIPQELLLGKHQLNELGSESAKIKAMGIMDKLSTDKIVKVLNILEKNIQDGSKLSTLLNHNNDTEDEERLWRDLIMERVTKSADACLTAINIMTSPNMPKAVYIEDVIERVIQYTKFHLQNTLYPQYDPVYRVDPLGGGLLSSKAKRAKCSTHKQRVIVMLYNKVCDIVSSLSELLEIQLLTDTTILQVSSMGITPFFVENVSELQLCAIKLVTAVFSRYEKHRQLILEEIFTSLARLPTSKRSLRNFRLNSSDTDGEPMYIQMVTALVLQLIQCVVHLPSAEKDSNSDEELNKKVDQDVLITNSYETAMRTAQNFLSIFLKKCGSKQGEEDYRPLFENFIQDLLSTVNKPEWPAAELLLSLLGRLLVHQFSNKSTEMALRVASLDYLGTVAARLRKDAVTSKMDQGSIARILKQASGGEDDIQQLQKALLDYLDENTETDASLVFSRKFYIAQWFRDTTMETEKAIKSQKDEDSSEGTHHAKDVETTGQIMHRAESRKKFLRSIIKTAPSQFSTLKIYSDTVDYEDACLIVRYLASMRPFAQSFDIYLTQILRVLGENAIAVRTKAMKCLSEVVAVDPSILARPDMQRGVHGRLMDNSTSVREAAVELLGRFVLCRPQLAEQYYDMLIERILDTGISVRKRVIKILRDICIEQPTFPKITEMCVKMIRRVNDEEGIKKLVNETFQKLWFTPTPHHDKEAMTRKILNITDVVAACRDTGYDWFEQLLQNLLKSEEDASYKPVKKACTQLVDNLVEHILKYEESLSDSDNKGVNSGRLVACITTLFLFSKIRPQLMVKHAMTMQPYLATKCSTQNDFMVICNVAKILELVVPLMEHPSETFLATIEEDLMKLIIKYGMTVVQHCVSCLGSVVNKVTQNYKFVWACFNRYYGALSKLKSQHQEDPNSTILTANKPALLRSLFTVGALCRHFDFDHEDFKGNSKVNIKDKVLELLMYFTKHSDEEVQTKAIIGLGFAFIQHPSLMFEQEVKTLYNSILSDKNCSVNLKIQVLKNLQTYLQEEDTRMQQADRDWKKVAKQEDLKEMGDISSGMSSSIMQLYLKQVLEAFFHTQSNVRHFALNVIALTLNQGLIHPVQCVPYLIAMGTDPEPSMRNKADQQLVEIDKKYAGFIHMKAVAGMKMSYQVQQAINTCPKDPVRGFRHDESSSALCSHLYSMIRGNRQHRRAFLISLLNLFDDTAKTEVNMLLYIADNLACFPYQTQEEPLFIMHHIDITLSVSGSNLLQSFKESMVKDKKKERKPSSDEETESDSNSGSESESEEEASKPRRLRKRVDSDSDSDEENDINAVMKCLPENSAPLIEFANVSQGILLLLMLKQHLKNLCGFSDSKIQKYSPSESAKVYDKAINRKTGVHFHPKQTLDFLRSDMANSKITEEVKRSIVKQYLDFKLLMEHLDPDEEEEDGEVSASTNARNKAITSLLGGGSPKNNAAETEDDESDGEDRGGGTSGSLRRSKRNSDSTELASQMNESVDVMDVIAICCPKYKDRPQIARVVQKTSNGFSVQWMAGSYSGSWTEAKRRDGRKLVPWVDTIKESDIIYKKIALTSANKLTNKVVQTLRSLYAAKDGTSS", "length": 2783, "header": "tr|F1NJ66-1|F1NJ66_CHICK Isoform 1 of Nipped-B protein OS=Gallus gallus OX=9031 GN=NIPBL PE=1 SV=2 CANONICAL=F1NJ66-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PVC0-1", "url": "https://www.uniprot.org/uniprotkb/F1NJ66/entry#A0A1D5PVC0-1", "sequence": { "sequence": "MNGDMPHVPITTLAGIASLTDLLNQLPLPSPLPATTTKSLLFNGRIAEEVNCLLACRDENLVSQLIHSLNQVSTDHIELKDNLGSDDPEGDTPVLLQAILARNPNVFREKSMQNRYGVQSGMMIPQFNISQNSMRGSPASSNYQQTTISHSPSSRFVPPQTSSGNRFLAQQNSPVPSPYAPQSPAGYMPYSHPPSYTPHPQLQQACPIVTAGMRNLHENKVSSQLSGNSANHHADNSRHGSNEDYLQMVHRLSSDDGDPSIRNAASFSLRSPQSVCSPAGSDGTPKDKPLKKRKQENKPQEAGGAAGGNRPASQESGSAGNGARPALMVSIDLQQAGRADSQATITQEFEAIKKPEEIKQYNDGFVCIPQEETVGVLKLKPENHPEIFRKKSDFEVQKTDIQQNENRQMEFQQNESRRLESKYNDNKQVEAKYDIKHDSRQMEMKQNENRQAESKQNESRQMEMKQNEGKQNNGKQEIRQRPETPKQKSEGRPETPKQKSEGRPETPKHRHDNRRDSSKPLSEKKIELSRHKPDVKSDTSKVKSDSRSDPVKQRPDGRSVSDTQRRDHDSLKQRSEDRESERYKGDPSKIRRTEFLRSSNRNEHDSKYGIKSDGSKPEKFERKHRHDSGESRERFSSGDQKSDQKSRPDSPRVKQDGKGDSSKSRPDKPGFRSPNSKDERRTDSSKSKVESNKAHPDNKAEFPSYLLGARSGALKHFVIPKIKRDKDGNVTQESRKTELKGEQKDKVEKIGLVEDLNKGAKPVVVLQKLSLDDVQKFIKDREDKSRGSCFKPNKNKSSKSNKGSIDQSVLKELPPELLAEIESTMPLCERVKMNKRKRSTVNEKPKYAEISSDEDNDSEEAFESSRKRHKKDRDEAWEYEEHDRRSSGDHRRSGHYHEGRRTSGSGRYRNRSPDDSDLDDYSPPPSLSEVARKMKKKEKQKKRRAYEPKLTPEEMMDSSTFKRFIASIENILENLEDMDFTTLGDDDEIPQELLLGKHQLNELGSESAKIKAMGIMDKLSTDKIVKVLNILEKNIQDGSKLSTLLNHNNDTEDEERLWRDLIMERVTKSADACLTAINIMTSPNMPKAVYIEDVIERVIQYTKFHLQNTLYPQYDPVYRVDPLGGGLLSSKAKRAKCSTHKQRVIVMLYNKVCDIVSSLSELLEIQLLTDTTILQVSSMGITPFFVENVSELQLCAIKLVTAVFSRYEKHRQLILEEIFTSLARLPTSKRSLRNFRLNSSDTDGEPMYIQMVTALVLQLIQCVVHLPSAEKDSNSDEELNKKVDQDVLITNSYETAMRTAQNFLSIFLKKCGSKQGEEDYRPLFENFIQDLLSTVNKPEWPAAELLLSLLGRLLVHQFSNKSTEMALRVASLDYLGTVAARLRKDAVTSKMDQGSIARILKQASGGEDDIQQLQKALLDYLDENTETDASLVFSRKFYIAQWFRDTTMETEKAIKSQKDEDSSEGTHHAKDVETTGQIMHRAESRKKFLRSIIKTAPSQFSTLKIYSDTVDYEDACLIVRYLASMRPFAQSFDIYLTQILRVLGENAIAVRTKAMKCLSEVVAVDPSILARPDMQRGVHGRLMDNSTSVREAAVELLGRFVLCRPQLAEQYYDMLIERILDTGISVRKRVIKILRDICIEQPTFPKITEMCVKMIRRVNDEEGIKKLVNETFQKLWFTPTPHHDKEAMTRKILNITDVVAACRDTGYDWFEQLLQNLLKSEEDASYKPVKKACTQLVDNLVEHILKYEESLSDSDNKGVNSGRLVACITTLFLFSKIRPQLMVKHAMTMQPYLATKCSTQNDFMVICNVAKILELVVPLMEHPSETFLATIEEDLMKLIIKYGMTVVQHCVSCLGSVVNKVTQNYKFVWACFNRYYGALSKLKSQHQEDPNSTILTANKPALLRSLFTVGALCRHFDFDHEDFKGNSKVNIKDKVLELLMYFTKHSDEEVQTKAIIGLGFAFIQHPSLMFEQEVKTLYNSILSDKNCSVNLKIQVLKNLQTYLQEEDTRMQQADRDWKKVAKQEDLKEMGDISSGMSSSIMQLYLKQVLEAFFHTQSNVRHFALNVIALTLNQGLIHPVQCVPYLIAMGTDPEPSMRNKADQQLVEIDKKYAGFIHMKAVAGMKMSYQVQQAINTCPKDPVRGFRHDESSSALCSHLYSMIRGNRQHRRAFLISLLNLFDDTAKTEVNMLLYIADNLACFPYQTQEEPLFIMHHIDITLSVSGSNLLQSFKESMVKDKKKERKPSSDEETESDSNSGSESESEEEASKPRRLRKRVDSDSDSDEENDINAVMKCLPENSAPLIEFANVSQGILLLLMLKQHLKNLCGFSDSKIQKYSPSESAKVYDKAINRKTGVHFHPKQTLDFLRSDMANSKITEEVKRSIVKQYLDFKLLMEHLDPDEEEEDGEVSASTNARNKAITSLLGGGSPKNNAAETEDDESDGEDRGGGTSGSLRRSKRNSDSTELASQMNESVDVMDVIAICCPKYKDRPQIARVVQKTSNGFSVQWMAGSYSGSWTEAKRRDGRKLVPWVDTIKESDIIYKKIALTSANKLTNKVVQTLRSLYAAKDGTSS", "length": 2572, "header": "tr|A0A1D5PVC0-1|A0A1D5PVC0_CHICK Computationally mapped isoform of Nipped-B protein OS=Gallus gallus OX=9031 GN=NIPBL PE=1 SV=1 CANONICAL=F1NJ66-1" }, "locus": { "chromosome": "Z", "start_pos": 12005907, "end_pos": 11910098, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033010.1", "url": "https://www.ensembl.org/id/ENSGALT00010033010.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019515.1", "url": "https://www.ensembl.org/id/ENSGALP00010019515.1" } ] } }, { "isoform_ac": "A0A8V0YFB3-1", "url": "https://www.uniprot.org/uniprotkb/F1NJ66/entry#A0A8V0YFB3-1", "sequence": { "sequence": "MNGDMPHVPITTLAGIASLTDLLNQLPLPSPLPATTTKSLLFNGRIAEEVNCLLACRDENLVSQLIHSLNQVSTDHIELKDNLGSDDPEGDTPVLLQAILARNPNVFREKSMQNRYGVQSGMMIPQFNISQNSMRGSPASSNYQQTTISHSPSSRFVPPQTSSGNRFLAQQNSPVPSPYAPQSPAGYMPYSHPPSYTPHPQLQQACPIVTAGMRNLHENKVSSQLSGNSANHHADNSRHGSNEDYLQMVHRLSSDDGDPSIRNAASFSLRSPQSVCSPAGSDGTPKGSRPPLILQSQPPPYSSPRDVPPDILLDSPERKQKKQKKMKLGKDEKDQTEKAAMYDIISSPSKDSTKLTLRLSRVRSSDLDQQDDMLSGLENSSVSEGDIPFNVQYPGQTSKTPVTPQDVNRPLNAAQCLPQHEQTAFLQAQQVPVLQQNTSVAAKQPQTPVVQTQQQVSQQGTITSYDEVELDALAEIERIERESAIERERFSKEVQDKDKPLKKRKQENKPQEAGGAAGGNRPASQESGSAGNGARPALMVSIDLQQAGRADSQATITQEFEAIKKPEEIKQYNDGFVCIPQEETVGVLKLKPENHPEIFRKKSDFEVQKTDIQQNENRQMEFQQNESRRLESKYNDNKQVEAKYDIKHDSRQMEMKQNENRQAESKQNESRQMEMKQNEGKQNNGKQEIRQRPETPKQKSEGRPETPKQKSEGRPETPKHRHDNRRDSSKPLSEKKIELSRHKPDVKSDTSKVKSDSRSDPVKQRPDGRSVSDTQRRDHDSLKQRSEDRESERYKGDPSKIRRTEFLRSSNRNEHDSKYGIKSDGSKPEKFERKHRHDSGESRERFSSGDQKSDQKSRPDSPRVKQDGKGDSSKSRPDKPGFRSPNSKDERRTDSSKSKVESNKAHPDNKAEFPSYLLGARSGALKHFVIPKIKRDKDGNVTQESRKTELKGEQKDKVEKIGLVEDLNKGAKPVVVLQKLSLDDVQKFIKDREDKSRGSCFKPNKNKSSKSNKGSIDQSVLKELPPELLAEIESTMPLCERVKMNKRKRSTVNEKPKYAEISSDEDNDSEEAFESSRKRHKKDRDEAWEYEEHDRRSSGDHRRSGHYHEGRRTSGSGRYRNRSPDDSDLDDYSPPPSLSEVARKMKKKEKQKKRRAYEPKLTPEEMMDSSTFKRFIASIENILENLEDMDFTTLGDDDEIPQELLLGKHQLNELGSESAKIKAMGIMDKLSTDKIVKVLNILEKNIQDGSKLSTLLNHNNDTEDEERLWRDLIMERVTKSADACLTAINIMTSPNMPKAVYIEDVIERVIQYTKFHLQNTLYPQYDPVYRVDPLGGGLLSSKAKRAKCSTHKQRVIVMLYNKVCDIVSSLSELLEIQLLTDTTILQVSSMGITPFFVENVSELQLCAIKLVTAVFSRYEKHRQLILEEIFTSLARLPTSKRSLRNFRLNSSDTDGEPMYIQMVTALVLQLIQCVVHLPSAEKDSNSDEELNKKVDQDVLITNSYETAMRTAQNFLSIFLKKCGSKQGEEDYRPLFENFIQDLLSTVNKPEWPAAELLLSLLGRLLVHQFSNKSTEMALRVASLDYLGTVAARLRKDAVTSKMDQGSIARILKQASGGEDDIQQLQKALLDYLDENTETDASLVFSRKFYIAQWFRDTTMETEKAIKSQKDEDSSEGTHHAKDVETTGQIMHRAESRKKFLRSIIKTAPSQFSTLKIYSDTVDYEDACLIVRYLASMRPFAQSFDIYLTQILRVLGENAIAVRTKAMKCLSEVVAVDPSILARPDMQRGVHGRLMDNSTSVREAAVELLGRFVLCRPQLAEQYYDMLIERILDTGISVRKRVIKILRDICIEQPTFPKITEMCVKMIRRVNDEEGIKKLVNETFQKLWFTPTPHHDKEAMTRKILNITDVVAACRDTGYDWFEQLLQNLLKSEEDASYKPVKKACTQLVDNLVEHILKYEESLSDSDNKGVNSGRLVACITTLFLFSKIRPQLMVKHAMTMQPYLATKCSTQNDFMVICNVAKILELVVPLMEHPSETFLATIEEDLMKLIIKYGMTVVQHCVSCLGSVVNKVTQNYKFVWACFNRYYGALSKLKSQHQEDPNSTILTANKPALLRSLFTVGALCRHFDFDHEDFKGNSKVNIKDKVLELLMYFTKHSDEEVQTKAIIGLGFAFIQHPSLMFEQEVKTLYNSILSDKNCSVNLKIQVLKNLQTYLQEEDTRMQQADRDWKKVAKQEDLKEMGDISSGMSSSIMQLYLKQVLEAFFHTQSNVRHFALNVIALTLNQGLIHPVQCVPYLIAMGTDPEPSMRNKADQQLVEIDKKYAGFIHMKAVAGMKMSYQVQQAINTCPKDPVRGFRHDESSSALCSHLYSMIRGNRQHRRAFLISLLNLFDDTAKTEVNMLLYIADNLACFPYQTQEEPLFIMHHIDITLSVSGSNLLQSFKESMVKDKKKERKPSSDEETESDSNSGSESESEEEASKPRRLRKRVDSDSDSDEENDINAVMKCLPENSAPLIEFANVSQGILLLLMLKQHLKNLCGFSDSKIQKYSPSESAKVYDKAINRKTGVHFHPKQTLDFLRSDMANSKITEEVKRSIVKQYLDFKLLMEHLDPDEEEEDGEVSASTNARNKAITSLLGGGSPKNNAAETEDDESDGEDRGGGTSGVRRRRSQRISQRIT", "length": 2676, "header": "tr|A0A8V0YFB3-1|A0A8V0YFB3_CHICK Computationally mapped isoform of Nipped-B protein OS=Gallus gallus OX=9031 GN=NIPBL PE=1 SV=1 CANONICAL=F1NJ66-1" }, "locus": { "chromosome": "Z", "start_pos": 12005008, "end_pos": 11910098, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033025.1", "url": "https://www.ensembl.org/id/ENSGALT00010033025.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019526.1", "url": "https://www.ensembl.org/id/ENSGALP00010019526.1" } ] } }, { "isoform_ac": "A0A8V0YNF6-1", "url": "https://www.uniprot.org/uniprotkb/F1NJ66/entry#A0A8V0YNF6-1", "sequence": { "sequence": "MNESVDVMDVIAICCPKYKDRPQIARVVQKTSNGFSVQWMAGSYSGSWTEAKRRDGRKLVPWVDTIKESDIIYKKIALTSANKLTNKVVQTLRSLYAAKDGTSS", "length": 104, "header": "tr|A0A8V0YNF6-1|A0A8V0YNF6_CHICK Computationally mapped isoform of NIPBL protein OS=Gallus gallus OX=9031 GN=NIPBL PE=4 SV=1 CANONICAL=F1NJ66-1" }, "locus": { "chromosome": "Z", "start_pos": 12005907, "end_pos": 12005596, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032981.1", "url": "https://www.ensembl.org/id/ENSGALT00010032981.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019502.1", "url": "https://www.ensembl.org/id/ENSGALP00010019502.1" } ] } }, { "isoform_ac": "F1NJ66-1", "url": "https://www.uniprot.org/uniprotkb/F1NJ66/entry#F1NJ66-1", "sequence": { "sequence": "MNGDMPHVPITTLAGIASLTDLLNQLPLPSPLPATTTKSLLFNGRIAEEVNCLLACRDENLVSQLIHSLNQVSTDHIELKDNLGSDDPEGDTPVLLQAILARNPNVFREKSMQNRYGVQSGMMIPQFNISQNSMRGSPASSNYQQTTISHSPSSRFVPPQTSSGNRFLAQQNSPVPSPYAPQSPAGYMPYSHPPSYTPHPQLQQACPIVTAGMRNLHENKVSSQLSGNSANHHADNSRHGSNEDYLQMVHRLSSDDGDPSIRNAASFSLRSPQSVCSPAGSDGTPKGSRPPLILQSQPPPYSSPRDVPPDILLDSPERKQKKQKKMKLGKDEKDQTEKAAMYDIISSPSKDSTKLTLRLSRVRSSDLDQQDDMLSGLENSSVSEGDIPFNVQYPGQTSKTPVTPQDVNRPLNAAQCLPQHEQTAFLQAQQVPVLQQNTSVAAKQPQTPVVQTQQQVSQQGTITSYDEVELDALAEIERIERESAIERERFSKEVQDKDKPLKKRKQENKPQEAGGAAGGNRPASQESGSAGNGARPALMVSIDLQQAGRADSQATITQEFEAIKKPEEIKQYNDGFVCIPQEETVGVLKLKPENHPEIFRKKSDFEVQKTDIQQNENRQMEFQQNESRRLESKYNDNKQVEAKYDIKHDSRQMEMKQNENRQAESKQNESRQMEMKQNEGKQNNGKQEIRQRPETPKQKSEGRPETPKQKSEGRPETPKHRHDNRRDSSKPLSEKKIELSRHKPDVKSDTSKVKSDSRSDPVKQRPDGRSVSDTQRRDHDSLKQRSEDRESERYKGDPSKIRRTEFLRSSNRNEHDSKYGIKSDGSKPEKFERKHRHDSGESRERFSSGDQKSDQKSRPDSPRVKQDGKGDSSKSRPDKPGFRSPNSKDERRTDSSKSKVESNKAHPDNKAEFPSYLLGARSGALKHFVIPKIKRDKDGNVTQESRKTELKGEQKDKVEKIGLVEDLNKGAKPVVVLQKLSLDDVQKFIKDREDKSRGSCFKPNKNKSSKSNKGSIDQSVLKELPPELLAEIESTMPLCERVKMNKRKRSTVNEKPKYAEISSDEDNDSEEAFESSRKRHKKDRDEAWEYEEHDRRSSGDHRRSGHYHEGRRTSGSGRYRNRSPDDSDLDDYSPPPSLSEVARKMKKKEKQKKRRAYEPKLTPEEMMDSSTFKRFIASIENILENLEDMDFTTLGDDDEIPQELLLGKHQLNELGSESAKIKAMGIMDKLSTDKIVKVLNILEKNIQDGSKLSTLLNHNNDTEDEERLWRDLIMERVTKSADACLTAINIMTSPNMPKAVYIEDVIERVIQYTKFHLQNTLYPQYDPVYRVDPLGGGLLSSKAKRAKCSTHKQRVIVMLYNKVCDIVSSLSELLEIQLLTDTTILQVSSMGITPFFVENVSELQLCAIKLVTAVFSRYEKHRQLILEEIFTSLARLPTSKRSLRNFRLNSSDTDGEPMYIQMVTALVLQLIQCVVHLPSAEKDSNSDEELNKKVDQDVLITNSYETAMRTAQNFLSIFLKKCGSKQGEEDYRPLFENFIQDLLSTVNKPEWPAAELLLSLLGRLLVHQFSNKSTEMALRVASLDYLGTVAARLRKDAVTSKMDQGSIARILKQASGGEDDIQQLQKALLDYLDENTETDASLVFSRKFYIAQWFRDTTMETEKAIKSQKDEDSSEGTHHAKDVETTGQIMHRAESRKKFLRSIIKTAPSQFSTLKIYSDTVDYEDACLIVRYLASMRPFAQSFDIYLTQILRVLGENAIAVRTKAMKCLSEVVAVDPSILARPDMQRGVHGRLMDNSTSVREAAVELLGRFVLCRPQLAEQYYDMLIERILDTGISVRKRVIKILRDICIEQPTFPKITEMCVKMIRRVNDEEGIKKLVNETFQKLWFTPTPHHDKEAMTRKILNITDVVAACRDTGYDWFEQLLQNLLKSEEDASYKPVKKACTQLVDNLVEHILKYEESLSDSDNKGVNSGRLVACITTLFLFSKIRPQLMVKHAMTMQPYLATKCSTQNDFMVICNVAKILELVVPLMEHPSETFLATIEEDLMKLIIKYGMTVVQHCVSCLGSVVNKVTQNYKFVWACFNRYYGALSKLKSQHQEDPNSTILTANKPALLRSLFTVGALCRHFDFDHEDFKGNSKVNIKDKVLELLMYFTKHSDEEVQTKAIIGLGFAFIQHPSLMFEQEVKTLYNSILSDKNCSVNLKIQVLKNLQTYLQEEDTRMQQADRDWKKVAKQEDLKEMGDISSGMSSSIMQLYLKQVLEAFFHTQSNVRHFALNVIALTLNQGLIHPVQCVPYLIAMGTDPEPSMRNKADQQLVEIDKKYAGFIHMKAVAGMKMSYQVQQAINTCPKDPVRGFRHDESSSALCSHLYSMIRGNRQHRRAFLISLLNLFDDTAKTEVNMLLYIADNLACFPYQTQEEPLFIMHHIDITLSVSGSNLLQSFKESMVKDKKKERKPSSDEETESDSNSGSESESEEEASKPRRLRKRVDSDSDSDEENDINAVMKCLPENSAPLIEFANVSQGILLLLMLKQHLKNLCGFSDSKIQKYSPSESAKVYDKAINRKTGVHFHPKQTLDFLRSDMANSKITEEVKRSIVKQYLDFKLLMEHLDPDEEEEDGEVSASTNARNKAITSLLGGGSPKNNAAETEDDESDGEDRGGGTSGSLRRSKRNSDSTELASQMNESVDVMDVIAICCPKYKDRPQIARVVQKTSNGFSVQWMAGSYSGSWTEAKRRDGRKLVPWVDTIKESDIIYKKIALTSANKLTNKVVQTLRSLYAAKDGTSS", "length": 2783, "header": "tr|F1NJ66-1|F1NJ66_CHICK Isoform 1 of Nipped-B protein OS=Gallus gallus OX=9031 GN=NIPBL PE=1 SV=2 CANONICAL=F1NJ66-1" }, "locus": { "chromosome": "Z", "start_pos": 12005907, "end_pos": 11910098, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033000.1", "url": "https://www.ensembl.org/id/ENSGALT00010033000.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019509.1", "url": "https://www.ensembl.org/id/ENSGALP00010019509.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-2470946", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2470946", "resource": "Reactome", "description": "Cohesin Loading onto Chromatin" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2K0J4-1", "protein_name": "Nipped-B protein", "gene_name": "Nipbl", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MNGDMPHVPITTLAGIASLTDLLNQLPLPSPLPATTTKSLLFNSRIAEEVNCLLACRDDNLVSQLVHSLNQVSTDHIELKDNLGSDDPEGDIPVLLQAVLARSPNVFREKSMQNRYVQSGMMMSQYKLSQNSMHSSPASSNYQQTTISHSPSSRFVPPQTSSGNRFMPQQNSPVPSPYAPQSPAGYMPYSHPSSYTTHPQMQQASVSSPIVAGGLRNIHDNKVSGPLSGNSANHHADNPRHGSSDDYLHMVHRLSSDDGDSSAMRNAASFPLRSPQPVCSPAGSDGTPKGSRPPLILQSQSLPCSSPRDVPPDILLDSPERKQKKQKKMKLGKDEKDQNEKAAMYDIISSPTKDSTKLTLRLSRVRSSDMDQQEDMLSGMENSNVSENDIPFNVQYPGQTSKTPITPQDVNRSLNAAQCLSQQEQTAFLPANQVPVLQQNTSVATKQPQTSVVQNQQQVSQQGPIYDEVELDALAEIERIERESAIERERFSKEVQDKDKPLKKRKQDSYPQEAGGATGGNRPASQETGSTGNGSRPALMVSIDLHQAGRADSQASLTQDSDNIKKPEETKQCNDAPISVLQEDSVGSLKSIPENHPETPKNKSDPELSKSEMKQNESRLSESKPNENQLGESKSNESKLETKTETQTEELKQSENKTTESKQSESAVVEPKQNENRLCDTKPNDNKQNNTRSENTKARPETPKQKAESRPETPKQKSEGRPETPKQKGDGRPETPKQKSEGRPETPKQKGEGRPETPKHRHENRKDSGKPSTEKKPDVSKHKQDIKSDSSRLKSERAEALKQRPDGRSESLRRDHDSKQKSDDRGESERHRGDQSRVRRPETLRSSSRNEHSTKSDGSKTEKLERKHRHESGDSRDRPSGEQKSRPDSPRVKQGDTNKSRPGFKSPNSKDDKRTEGNRSKVDSNKAHTDNKAEFPSYLLGGRSSALKNFVIPKIKRDKDGNITQETKKMDMKGEQKDKVEKMGLVEDLNKGAKPVVVLQKLSLDDVQKLIKDREEKSRSSLKSLKNKPSKSNKGSIDQSVLKELPPELLAEIESTMPLCERVKMNKRKRSTVNEKPKYAEISSDEDNDSDEAFESSRKRHKKDDDKAWEYEERDRRSSGDHRRSGHSHDGRRSSGGGRYRNRSPSDSDMEDYSPPPSLSEVARKMKKKEKQKKRKAYEPKLTPEEMMDSSTFKRFTASIENILDNLEDMDFTAFGDDDEIPQELLLGKHQLNELGSESAKIKAMGIMDKLSTDKTVKVLNILEKNIQDGSKLSTLLNHNNDTEEEERLWRDLIMERVTKSADACLTTINIMTSPNMPKAVYIEDVIERVIQYTKFHLQNTLYPQYDPVYRLDPHGGGLLSSKAKRAKCSTHKQRVIVMLYNKVCDIVSSLSELLEIQLLTDTTILQVSSMGITPFFVENVSELQLCAIKLVTAVFSRYEKHRQLILEEIFTSLARLPTSKRSLRNFRLNSSDVDGEPMYIQMVTALVLQLIQCVVHLPSSEKDPNSEEDSNKKVDQDVVITNSYETAMRTAQNFLSIFLKKCGSKQGEEDYRPLFENFVQDLLSTVNKPEWPAAELLLSLLGRLLVHQFSNKSTEMALRVASLDYLGTVAARLRKDAVTSKMDQGSIERILKQVSGGEDEIQQLQKALLDYLDENTETDPSLVFSRKFYIAQWFRDTTLETEKAMKSQKDEESSDGAHHAKEIETTGQIMHRAESRKRFLRSIIKTTPSQFSTLKMNSDTVDYDDACLIVRYLASMRPFAQSFDIYLTQILRVLGENAIAVRTKAMKCLSEVVAVDPSILARLDMQRGVHGRLMDNSTSVREAAVELLGRFVLCRPQLAEQYYDMLIERILDTGISVRKRVIKILRDICIEQPTFPKITEMCVKMIRRVNDEEGIKKLVNETFQKLWFTPTPHNDKEAMTRKILNITDVVAACRDTGYDWFEQLLQNLLKSEEDSSYKPVKKACTQLVDNLVEHILKYEESLADSDNKGVNSGRLVACITTLFLFSKIRPQLMVKHAMTMQPYLTTKCSTQNDFMVICNVAKILELVVPLMEHPSETFLATIEEDLMKLIIKYGMTVVQHCVSCLGAVVNKVTQNFKFVWACFNRYYGAISKLKSQHQEDPNNTSLLTNKPALLRSLFTVGALCRHFDFDLEDFKGNSKVNIKDKVLELLMYFTKHSDEEVQTKAIIGLGFAFIQHPSLMFEQEVKNLYNSILSDKNSSVNLKIQVLKNLQTYLQEEDTRMQQADRDWKKVAKQEDLKEMGDVSSGMSSSIMQLYLKQVLEAFFHTQSSVRHFALNVIALTLNQGLIHPVQCVPYLIAMGTDPEPAMRNKADQQLVEIDKKYAGFIHMKAVAGMKMSYQVQQAINTCLKDPVRGFRQDESSSALCSHLYSMIRGNRQHRRAFLISLLNLFDDTAKTEVTMLLYIADNLACFPYQTQEEPLFIMHHIDITLSVSGSNLLQSFKESMVKDKRKERKTSPAKENESSESEEEVCRPRKSRKRVDSESDSDSEDDVNSVMKCLPENSAPLIEFANVSQGILLLLMLKQHLKNLCGFSDSKIQKYSPSESAKVYDKAINRKTGVHFHPKQTLDFLRSDMANSKLTEDVKRSIVRQYLDFKLLMEHLDPDEEEEEGEVSASTNARNKAITSLLGGGSPKNNPAADTEDEESDGEDRGGGTSGSLRRSKRNSDSTELAAQMNESVDVMDVIAICCPKYKDRPQIARVVQRTSSGVSVQWMAGSYSGSWTEAKRRDGRKLVPWVDTIKESDIIYKKIALTSANKLTNKVVQTLRSLYAAKDGTSS", "length": 2798 }, "evidence": [ { "id": "F1NJ66", "url": "https://omabrowser.org/oma/group/F1NJ66/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8C2N1I0-1", "protein_name": "Nipped-B protein", "gene_name": "Nipbl", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MNGDMPHVPITTLAGIASLTDLLNQLPLPSPLPATTTKSLLFNSRIAEEVNCLLACRDDNLVSQLVHSLNQVSTDHIELKDNLGSDDPEGDIPVLLQAVLARSPNVFREKSMQNRYVQSGMMMSQYKLSQNSMHSSPASSNYQQTTISHSPSSRFVPPQTSSGNRFMPQQNSPVPSPYAPQSPAGYMPYSHPSSYTTHPQMQQASVSSPIVAGSLRNIHDNKVSGPLSGNSANHHADNPRHGSSDDYLHMVHRLSSDDGDSSTMRNAASFPLRSPQPVCSPAGSDGTPKGSRPPLILQSQSLPCSSPRDVPPDILLDSPERKQKKQKKMKLGKDEKDQNEKAAMYDIISSPTKDSTKLTLRLSRVKSSDMDQQEDMLSGMENSNVSENDIPFNVQYPGQTSKTPITPQEVNRPLNAAQCLSQQEQTAFLPANQVPVLQQNTSVAAKQPQTSVVQNQQQVSQQGPIYDEVELDALAEIERIERESAIERERFSKEVQDKDKPLKKRKQDSYPQEAGGATGGNRPASQETGSTGNGSRPALMVSIDLHQAGRVDSQASITQDSDSIKKPEEMKQCNDAPISVLQEDIIGSLKSIPENHPETPKKKSEPELSKSEVKQNESRLSESKPNENQLLETKSSESKLETKTETQTEELKQNENKTTECKQNESTVVEPKQSENRLCDAKPNDNKQNNTRSETTKSRPETPKQKAESRPETPKQKGEGRPETPKQKGEGRPETPKQKGEGRPETPKQKGEGRPETPKHRHENRRDAGKPSTDKKPDVSKHKQDIKSDSPRLKSERAEALKQRPDGRSESLRRDHDSKQKSDDRGESERHRGDQARVRRPETLRSSSRNEHSIKSDGSKTEKLERKHRHESGDSRDRLSSGEQKSRPDSPRVKQGDTNKSRPGFKSPNSKDDKRTEGNRSKVDSNKAHTDNKAEFPSYLLGGRSGALKNFVIPKIKRDKDGNITQETKKMDMKGDQKDKVEKMGLVEDLNKGAKPVVVLQKLSLDDVQKLIKDREEKSRSSLKSIKNKPSKSNKGSIDQSVLKELPPELLAEIESTMPLCERVKMNKRKRSTVNEKPKYAEISSDEDNDSDEAFESSRKRHKKDDDKAWEYEERDRRSSGDHRRSGHSHEGRRSSGGGRYRNRSPSDSDMEDYSPPPSLSEVARKMKKKEKQKKRKAYEPKLTPEEMMDSSTFKRFTASIENILDNLEDMDFTAFGDDDEIPQELLLGKHQLNELGSESAKIKAMGIMDKLSTDKTVKVLNILEKNIQDGSKLSTLLNHNNDTEEEERLWRDLIMERVTKSADACLTTINIMTSPNMPKAVYIEDVIERVIQYTKFHLQNTLYPQYDPVYRLDPHGGGLLSSKAKRAKCSTHKQRVIVMLYNKVCDIVSSLSELLEIQLLTDTTILQVSSMGITPFFVENVSELQLCAIKLVTAVFSRYEKHRQLILEEIFTSLARLPTSKRSLRNFRLNSSDVDGEPMYIQMVTALVLQLIQCVVHLPSSEKDPNSEEDSNKKVDQDVLITNSYETAMRTAQNFLSIFLKKCGSKQGEEDYRPLFENFVQDLLSTVNKPEWPAAELLLSLLGRLLVHQFSNKSTEMALRVASLDYLGTVAARLRKDAVTSKMDQGSIERILKQVSGGEDEIQQLQKALLDYLDENTETDPSLVFSRKFYIAQWFRDTTLETEKAMKSQKDEESSDGAHHAKEIETTGQIMHRAENRKKFLRSIIKTTPSQFSTLKMNSDTVDYDDACLIVRYLASMRPFAQSFDIYLTQILRVLGENAIAVRTKAMKCLSEVVAVDPSILARLDMQRGVHGRLMDNSTSVREAAVELLGRFVLCRPQLAEQYYDMLIERILDTGISVRKRVIKILRDICIEQPTFPKITEMCVKMIRRVNDEEGIKKLVNETFQKLWFTPTPHNDKEAMTRKILNITDVVAACRDTGYDWFEQLLQNLLKSEEDSSYKPVKKACTQLVDNLVEHILKYEESLADSDNKGVNSGRLVACITTLFLFSKIRPQLMVKHAMTMQPYLTTKCSTQNDFMVICNVAKILELVVPLMEHPSETFLATIEEDLMKLIIKYGMTVVQHCVSCLGAVVNKVTQNFKFVWACFNRYYGAISKLKSQHQEDPNNTSLLTNKPALLRSLFTVGALCRHFDFDLEDFKGNSKVNIKDKVLELLMYFTKHSDEEVQTKAIIGLGFAFIQHPSLMFEQEVKNLYNNILSDKNSSVNLKIQVLKNLQTYLQEEDTRMQQADRDWKKVAKQEDLKEMGDVSSGMSSSIMQLYLKQVLEAFFHNQSNVRHFALNVIALTLNQGLIHPVQCVPYLIAMGTDPEPAMRNKADQQLVEIDKKYAGFIHMKAVAGMKMSYQVQQAINDDGKDPVRGFRQDESSSALCSHLYTMIRGNRQHRRAFLISLLNLFDDTAKTEVTMLLYIADNLACFPYQTQEEPLFIMHHIDITLSVSGSNLLQSFKESMVKDKRKERKASPTKENESSESEEEVSRPRKSRKRVDSDSDSDSEDDVNSVMKCLPENSAPLIEFANVSQGILLLLMLKQHLKNLCGFSDSKIQKYSPSESAKVYDKAINRKTGVHFHPKQTLDFLRSDMANSKLTEEVKRSIVRQYLDFKLLMEHLDPDEEEEEGEVSASTNARNKAITSLLGGGSPKNNTAAETEDDESDGEDRGGGTSGSLRRSKRNSDSTELAAQMNESVDVMDVIAICCPKYKDRPQIARVVQKTSSGFSVQWMAGSYSGSWTEAKRRDGRKLVPWVDTIKESDIIYKKIALTSANKLTNKVVQTLRSLYAAKDGTSS", "length": 2799 }, "evidence": [ { "id": "F1NJ66", "url": "https://omabrowser.org/oma/group/F1NJ66/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "E1BKC4-1", "protein_name": "Nipped-B protein", "gene_name": "NIPBL", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MNGDMPHVPITTLAGIASLTDLLNQLPLPSPLPATTTKSLLFNARIAEEVNCLLACRDDNLVSQLVHSLNQVSTDHIELKDNLGSDDPEGDIPVLLQAVLARSPNVFREKSMQNRYVQSGMMMSQYKLSQNSMHSSPASSNYQQTTISHSPSSRFVPPQTSSGNRFMPQQNSPVPSPYAPQSPAGYMPYSHPSSYTTHPQMQQASVSSPIVAGGLRNLHDNKVSGSLSGNSANHHADNPRHGSSDDYLHMVHRISSDDGDSSTMRNAASFPLRSPQPVCSPAGSDGTPKGSRPSLILQSQSLPCSSPRDVPPDILLDSPERKQKKQKKMKLGKDEKDQNEKAAMYDIISSPSKDSTKLTLRLTRVRSSDMDQQEDMLSGMENSNVSENDIPFNVQYPGQTSKTPITPQDVNRPLNAAQCLSQQEQTAFLPANQVPVLQQNTSVATKQPQTSVVLNQQQVSQQGPIYDEVELDALAEIERIERESAIERERFSKEVQDKDKPLKKRKQDSYPQEAGGATGGNRPASQETGSTGNGSRPALMVSIDLHQAGRVDSQASITQDSDSIKKPEEIKQCNDTPISVLQEDIIGNLKSTPENHPETPKKKSDPELLKSEVKQNESRLAESKPNENRLVETKSSETKLETKIEVPTEEPKQNENRMIESRQNESSTAEPKQNENRLPDTKPNDNKQNNGRSETTKSRPETPKQKGESRPETPKQKSDGRPETPKQKGDGRPETPKQKGEGRPETPKQKNEGRPETPKHRHENRRDSGKPSTEKKPEVSKHKQDIKSDSPRLKSERAEALKQRPDGRSISESLRRDHDSKQKSDDRSESERHRGDQSRVRRPETLRSSSRNDHGIKSDGSKPDKLERKHRHESGDSRERPSSGEQKSRPDSPRVKQGDSNKSRPDKPGFKSPNSKDDRRTEGNKSKVDSNKTHPDNKAEFPSYLLGGRSGALKNFVIPKIKRDKDGNITQETKKMEMKGEQKDKVEKMGLVEDLNKGAKPVVVLQKLSLDDVQKLIKDREDKSRSSLKPIKNKPSKSNKGSIDQSVLKELPPELLAEIESTMPLCERVKMNKRKRSTVNEKPKYAEISSDEDNDSDETFESSRKRHKKDDDKAWEYEERDRRSSGDHRRSGHSHEGRRSSGGGRYRNRSPSDSDMEDYSPPPSLSEVARKMKKKEKQKKRKAYEPKLTPEEMMDSSTFKRFTASIENILDNLEDMDFTAFGDDDEIPQELLLGKHQLNELGSESAKIKAMGIMDKLSTDKTVKVLNILEKNIQDGSKLSTLLNHNNDTEEEERLWRDLIMERVTKSADACLTTINIMTSPNMPKAVYIEDVIERVIQYTKFHLQNTLYPQYDPVYRLDPHGGGLLSSKAKRAKCSTHKQRVIVMLYNKVCDIVSSLSELLEIQLLTDTTILQVSSMGITPFFVENVSELQLCAIKLVTAVFSRYEKHRQLILEEIFTSLARLPTSKRSLRNFRLNSSDMDGEPMYIQMVTALVLQLIQCVVHLPSSEKDSNSEEDSNKKVDQDVIITNSYETAMRTAQNFLSIFLKKCGSKQGEEDYRPLFENFVQDLLSTVNKPEWPAAELLLSLLGRLLVHQFSNKSTEMALRVASLDYLGTVAARLRKDAVTSKMDQGSIERILKQVSGGEDEIQQLQKALLDYLDENTETDPSLVFSRKFYIAQWFRDTTLETEKAMKSQKDEESSEGSHHAKEVETTGQIMHRAENRKKFLRSIIKTTPSQFSTLKMNSDTVDYDDACLIVRYLASMRPFAQSFDIYLTQILRVLGENAIAVRTKAMKCLSEVVAVDPSILARLDMQRGVHGRLMDNSTSVREAAVELLGRFVLCRPQLAEQYYDMLIERILDTGISVRKRVIKILRDICIEQPTFPKITEMCVKMIRRVNDEEGIKKLVNETFQKLWFTPTPHNDKEAMTRKILNITDVVAACRDTGYDWFEQLLQNLLKSEEDSSYKPVKKACTQLVDNLVEHILKYEESLADSDNKGVNSGRLVACITTLFLFSKIRPQLMVKHAMTMQPYLTTKCSTQNDFMVICNVAKILELVVPLMEHPSETFLATIEEDLMKLIIKYGMTVVQHCVSCLGAVVNKVTQNFKFVWACFNRYYGAISKLKSQHQEDPNNTSLLTNKPALLRSLFTVGALCRHFDFDLEDFKGNSKVNIKDKVLELLMYFTKHSDEEVQTKAIIGLGFAFIQHPSLMFEQEVKNLYNNILSDKNSSVNLKIQVLKNLQTYLQEEDTRMQQADRDWKKVAKQEDLKEMGDVSSGMSSSIMQLYLKQVLEAFFHTQSSVRHFALNVIALTLNQGLIHPVQCVPYLIAMGTDPEPAMRNKADQQLVEIDKKYAGFIHMKAVAGMKMSYQVQQAINTCLKDPVRGFRQDESSSALCSHLYSMIRGNRQHRRAFLISLLNLFDDTAKTEVNMLLYIADNLACFPYQTQEEPLFIMHHIDITLSVSGSNLLQSFKESMVKDKRKERKSSPGKENESSESEEEVSRPRKSRKRVDSDSDSDSEDDINSVMKCLPENSAPLIEFANVSQGILLLLMLKQHLKNLCGFSDSKIQKYSPSESAKVYDKAINRKTGVHFHPKQTLDFLRSDMANSKITEDVKRSIVKQYLDFKLLMEHLDPDEEEEEGEVSASTNARNKAITSLLGGGSPKNNAAAETEDDESDGEDRGGGTSGSLRRSKRNSDSTELAAQMNESVDVMDVIAICCPKYKDRPQIARVVQKTSSGFSVQWMAGSYSGSWTEAKRRDGRKLVPWVDTIKESDIIYKKIALTSANKLTNKVVQTLRSLYAAKDGTSS", "length": 2804 }, "evidence": [ { "id": "F1NJ66", "url": "https://omabrowser.org/oma/group/F1NJ66/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q6KC79-1", "protein_name": "Nipped-B-like protein", "gene_name": "NIPBL", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNGDMPHVPITTLAGIASLTDLLNQLPLPSPLPATTTKSLLFNARIAEEVNCLLACRDDNLVSQLVHSLNQVSTDHIELKDNLGSDDPEGDIPVLLQAVLARSPNVFREKSMQNRYVQSGMMMSQYKLSQNSMHSSPASSNYQQTTISHSPSSRFVPPQTSSGNRFMPQQNSPVPSPYAPQSPAGYMPYSHPSSYTTHPQMQQASVSSPIVAGGLRNIHDNKVSGPLSGNSANHHADNPRHGSSEDYLHMVHRLSSDDGDSSTMRNAASFPLRSPQPVCSPAGSEGTPKGSRPPLILQSQSLPCSSPRDVPPDILLDSPERKQKKQKKMKLGKDEKEQSEKAAMYDIISSPSKDSTKLTLRLSRVRSSDMDQQEDMISGVENSNVSENDIPFNVQYPGQTSKTPITPQDINRPLNAAQCLSQQEQTAFLPANQVPVLQQNTSVAAKQPQTSVVQNQQQISQQGPIYDEVELDALAEIERIERESAIERERFSKEVQDKDKPLKKRKQDSYPQEAGGATGGNRPASQETGSTGNGSRPALMVSIDLHQAGRVDSQASITQDSDSIKKPEEIKQCNDAPVSVLQEDIVGSLKSTPENHPETPKKKSDPELSKSEMKQSESRLAESKPNENRLVETKSSENKLETKVETQTEELKQNESRTTECKQNESTIVEPKQNENRLSDTKPNDNKQNNGRSETTKSRPETPKQKGESRPETPKQKSDGHPETPKQKGDGRPETPKQKGESRPETPKQKNEGRPETPKHRHDNRRDSGKPSTEKKPEVSKHKQDTKSDSPRLKSERAEALKQRPDGRSVSESLRRDHDNKQKSDDRGESERHRGDQSRVRRPETLRSSSRNEHGIKSDSSKTDKLERKHRHESGDSRERPSSGEQKSRPDSPRVKQGDSNKSRSDKLGFKSPTSKDDKRTEGNKSKVDTNKAHPDNKAEFPSYLLGGRSGALKNFVIPKIKRDKDGNVTQETKKMEMKGEPKDKVEKIGLVEDLNKGAKPVVVLQKLSLDDVQKLIKDREDKSRSSLKPIKNKPSKSNKGSIDQSVLKELPPELLAEIESTMPLCERVKMNKRKRSTVNEKPKYAEISSDEDNDSDEAFESSRKRHKKDDDKAWEYEERDRRSSGDHRRSGHSHEGRRSSGGGRYRNRSPSDSDMEDYSPPPSLSEVARKMKKKEKQKKRKAYEPKLTPEEMMDSSTFKRFTASIENILDNLEDMDFTAFGDDDEIPQELLLGKHQLNELGSESAKIKAMGIMDKLSTDKTVKVLNILEKNIQDGSKLSTLLNHNNDTEEEERLWRDLIMERVTKSADACLTTINIMTSPNMPKAVYIEDVIERVIQYTKFHLQNTLYPQYDPVYRLDPHGGGLLSSKAKRAKCSTHKQRVIVMLYNKVCDIVSSLSELLEIQLLTDTTILQVSSMGITPFFVENVSELQLCAIKLVTAVFSRYEKHRQLILEEIFTSLARLPTSKRSLRNFRLNSSDMDGEPMYIQMVTALVLQLIQCVVHLPSSEKDSNAEEDSNKKIDQDVVITNSYETAMRTAQNFLSIFLKKCGSKQGEEDYRPLFENFVQDLLSTVNKPEWPAAELLLSLLGRLLVHQFSNKSTEMALRVASLDYLGTVAARLRKDAVTSKMDQGSIERILKQVSGGEDEIQQLQKALLDYLDENTETDPSLVFSRKFYIAQWFRDTTLETEKAMKSQKDEESSEGTHHAKEIETTGQIMHRAENRKKFLRSIIKTTPSQFSTLKMNSDTVDYDDACLIVRYLASMRPFAQSFDIYLTQILRVLGENAIAVRTKAMKCLSEVVAVDPSILARLDMQRGVHGRLMDNSTSVREAAVELLGRFVLCRPQLAEQYYDMLIERILDTGISVRKRVIKILRDICIEQPTFPKITEMCVKMIRRVNDEEGIKKLVNETFQKLWFTPTPHNDKEAMTRKILNITDVVAACRDTGYDWFEQLLQNLLKSEEDSSYKPVKKACTQLVDNLVEHILKYEESLADSDNKGVNSGRLVACITTLFLFSKIRPQLMVKHAMTMQPYLTTKCSTQNDFMVICNVAKILELVVPLMEHPSETFLATIEEDLMKLIIKYGMTVVQHCVSCLGAVVNKVTQNFKFVWACFNRYYGAISKLKSQHQEDPNNTSLLTNKPALLRSLFTVGALCRHFDFDLEDFKGNSKVNIKDKVLELLMYFTKHSDEEVQTKAIIGLGFAFIQHPSLMFEQEVKNLYNNILSDKNSSVNLKIQVLKNLQTYLQEEDTRMQQADRDWKKVAKQEDLKEMGDVSSGMSSSIMQLYLKQVLEAFFHTQSSVRHFALNVIALTLNQGLIHPVQCVPYLIAMGTDPEPAMRNKADQQLVEIDKKYAGFIHMKAVAGMKMSYQVQQAINTCLKDPVRGFRQDESSSALCSHLYSMIRGNRQHRRAFLISLLNLFDDTAKTDVTMLLYIADNLACFPYQTQEEPLFIMHHIDITLSVSGSNLLQSFKESMVKDKRKERKSSPSKENESSDSEEEVSRPRKSRKRVDSDSDSDSEDDINSVMKCLPENSAPLIEFANVSQGILLLLMLKQHLKNLCGFSDSKIQKYSPSESAKVYDKAINRKTGVHFHPKQTLDFLRSDMANSKITEEVKRSIVKQYLDFKLLMEHLDPDEEEEEGEVSASTNARNKAITSLLGGGSPKNNTAAETEDDESDGEDRGGGTSGSLRRSKRNSDSTELAAQMNESVDVMDVIAICCPKYKDRPQIARVVQKTSSGFSVQWMAGSYSGSWTEAKRRDGRKLVPWVDTIKESDIIYKKIALTSANKLTNKVVQTLRSLYAAKDGTSS", "length": 2804 }, "evidence": [ { "id": "F1NJ66", "url": "https://omabrowser.org/oma/group/F1NJ66/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q6KCD5-1", "protein_name": "Nipped-B-like protein", "gene_name": "Nipbl", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNGDMPHVPITTLAGIASLTDLLNQLPLPSPLPATTTKSLLFNSRIAEEVNCLLACRDDNLVSQLVHSLNQVSTDHIELKDNLGSDDPEGDIPVLLQAVLARSPNVFREKSMQNRYVQSGMMMSQYKLSQNSMHSSPASSNYQQTTISHSPSSRFVPPQTSSGNRFMPQQNSPVPSPYAPQSPAGYMPYSHPSSYTTHPQMQQASVSSPIVAGGLRNIHDNKVSGPLSGNSANHHADNPRHGSSDDYLHMVHRLSSDDGDSSTMRNAASFPLRSPQPVCSPAGSDGTPKGSRPPLILQSQSLPCSSPRDVPPDILLDSPERKQKKQKKIKLGKDEKDQNEKAAMYDIISSPTKDSTKLTLRLSRVRSSDMDQQDDMLSGMENSNVSENDIPFNVQYPGQTSKTPITPQDVNRPLNAAQCLSQQEQTAFLPANQVPVLQQNTSVATKQPQTSVVQNQQQVSQQGPIYDEVELDALAEIERIERESAIERERFSKEVQDKDKPLKKRKQDSYPQEAGGATGGNRPASQETGSTGNGSRPALMVSIDLHQAGRVDSQASITQDSDSIKKPEETKQCNDAPISVLQEDIVGSLKSIPENHPETPKKKSDPELSKSEMKQNESRLSESKPNENQLGESKSNESKLETKTETPTEELKQNENKTTESKQSESAVVEPKQNENRPCDTKPNDNKQNNTRSENTKARPETPKQKAESRPETPKQKSEGRPETPKQKGDGRPETPKQKSEGRPETPKQKGEGRPETPKHRHENRRDSGKPSTEKKPDVSKHKQDIKSDSPRLKSERAEALKQRPDGRWESLRRDHDSKQKSDDRGESERHRGDQSRVRRPETLRSSSRNDHSTKSDGSKTEKLERKHRHESGDSRDRPSGEQKSRPDSPRVKQGDTNKSRPGFKSPNSKDDKRTEGNRSKVDSNKAHTDNKAEFPSYLLGGRSGALKNFVIPKIKRDKDGNITQETKKMDMKGEQKDKVEKMGLVEDLNKGAKPVVVLQKLSLDDVQKLIKDREEKSRSSLKSIKNKPSKSNKGSIDQSVLKELPPELLAEIESTMPLCERVKMNKRKRSTVNEKPKYAEISSDEDNDSDEAFESSRKRHKKDDDKAWEYEERDRRSSGDHRRSGHSHDGRRSSGGGRYRNRSPSDSDMEDYSPPPSLSEVARKMKKKEKQKKRKAYEPKLTPEEMMDSSTFKRFTASIENILDNLEDMDFTAFGDDDEIPQELLLGKHQLNELGSESAKIKAMGIMDKLSTDKTVKVLNILEKNIQDGSKLSTLLNHNNDTEEEERLWRDLIMERVTKSADACLTTINIMTSPNMPKAVYIEDVIERVIQYTKFHLQNTLYPQYDPVYRVDPHGGGLLSSKAKRAKCSTHKQRVIVMLYNKVCDIVSSLSELLEIQLLTDTTILQVSSMGITPFFVENVSELQLCAIKLVTAVFSRYEKHRQLILEEIFTSLARLPTSKRSLRNFRLNSSDVDGEPMYIQMVTALVLQLIQCVVHLPSSEKDPNSEEDSNKKVDQDVVITNSYETAMRTAQNFLSIFLKKCGSKQGEEDYRPLFENFVQDLLSTVNKPEWPAAELLLSLLGRLLVHQFSNKSTEMALRVASLDYLGTVAARLRKDAVTSKMDQGSIERILKQVSGGEDEIQQLQKALLDYLDENTETDPSLVFSRKFYIAQWFRDTTLETEKAMKSQKDEESSDATHHAKELETTGQIMHRAENRKKFLRSIIKTTPSQFSTLKMNSDTVDYDDACLIVRYLASMRPFAQSFDIYLTQILRVLGENAIAVRTKAMKCLSEVVAVDPSILARLDMQRGVHGRLMDNSTSVREAAVELLGRFVLCRPQLAEQYYDMLIERILDTGISVRKRVIKILRDICIEQPTFPKITEMCVKMIRRVNDEEGIKKLVNETFQKLWFTPTPHNDKEAMTRKILNITDVVAACRDTGYDWFEQLLQNLLKSEEDSSYKPVKKACTQLVDNLVEHILKYEESLADSDNKGVNSGRLVACITTLFLFSKIRPQLMVKHAMTMQPYLTTKCSTQNDFMVICNVAKILELVVPLMEHPSETFLATIEEDLMKLIIKYGMTVVQHCVSCLGAVVNKVTQNFKFVWACFNRYYGAISKLKSQHQEDPNNTSLLTNKPALLRSLFTVGALCRHFDFDLEDFKGNSKVNIKDKVLELLMYFTKHSDEEVQTKAIIGLGFAFIQHPSLMFEQEVKNLYNSILSDKNSSVNLKIQVLKNLQTYLQEEDTRMQQADRDWKKVAKQEDLKEMGDVSSGMSSSIMQLYLKQVLEAFFHTQSSVRHFALNVIALTLNQGLIHPVQCVPYLIAMGTDPEPAMRNKADQQLVEIDKKYAGFIHMKAVAGMKMSYQVQQAINTCLKDPVRGFRQDESSSALCSHLYSMIRGNRQHRRAFLISLLNLFDDTAKTEVTMLLYIADNLACFPYQTQEEPLFIMHHIDITLSVSGSNLLQSFKESMVKDKRKERKTSPAKENESSESEEEVSRPRKSRKRVDSESDSDSEDDINSVMKCLPENSAPLIEFANVSQGILLLLMLKQHLKNLCGFSDSKIQKYSPSESAKVYDKAINRKTGVHFHPKQTLDFLRSDMANSKLTEDVKRSIVRQYLDFKLLMEHLDPDEEEEEGEVSASTNARNKAITSLLGGGSPKNNTAADTEDEESDGEDRGGGTSGSLRRSKRNSDSTELAAQMNESVDVMDVIAICCPKYKDRPQIARVVQRTSSGVSVQWMAGSYSGSWTEAKRRDGRKLVPWVDTIKESDIIYKKIALTSANKLTNKVVQTLRSLYAAKDGTSS", "length": 2798 }, "evidence": [ { "id": "F1NJ66", "url": "https://omabrowser.org/oma/group/F1NJ66/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 12, "go_terms": [ { "name": "regulation of gene expression", "id": "GO:0010468", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010468", "evidence": [ { "database": "UniProtKB", "id": "F1NJ66", "url": "https://www.uniprot.org/uniprotkb/F1NJ66" } ], "pmid": "" }, { "name": "chromatin looping", "id": "GO:0140588", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140588", "evidence": [ { "database": "UniProtKB", "id": "F1NJ66", "url": "https://www.uniprot.org/uniprotkb/F1NJ66" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "F1NJ66", "url": "https://www.uniprot.org/uniprotkb/F1NJ66" } ], "pmid": "" }, { "name": "brain development", "id": "GO:0007420", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007420", "evidence": [ { "database": "UniProtKB", "id": "F1NJ66", "url": "https://www.uniprot.org/uniprotkb/F1NJ66" } ], "pmid": "" }, { "name": "heart morphogenesis", "id": "GO:0003007", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003007", "evidence": [ { "database": "UniProtKB", "id": "F1NJ66", "url": "https://www.uniprot.org/uniprotkb/F1NJ66" } ], "pmid": "" }, { "name": "digestive tract development", "id": "GO:0048565", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048565", "evidence": [ { "database": "UniProtKB", "id": "F1NJ66", "url": "https://www.uniprot.org/uniprotkb/F1NJ66" } ], "pmid": "" }, { "name": "establishment of mitotic sister chromatid cohesion", "id": "GO:0034087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034087", "evidence": [ { "database": "UniProtKB", "id": "F1NJ66", "url": "https://www.uniprot.org/uniprotkb/F1NJ66" } ], "pmid": "" }, { "name": "embryonic viscerocranium morphogenesis", "id": "GO:0048703", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048703", "evidence": [ { "database": "UniProtKB", "id": "F1NJ66", "url": "https://www.uniprot.org/uniprotkb/F1NJ66" } ], "pmid": "" }, { "name": "establishment of protein localization to chromatin", "id": "GO:0071169", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071169", "evidence": [ { "database": "UniProtKB", "id": "F1NJ66", "url": "https://www.uniprot.org/uniprotkb/F1NJ66" } ], "pmid": "" }, { "name": "replication-born double-strand break repair via sister chromatid exchange", "id": "GO:1990414", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990414", "evidence": [ { "database": "UniProtKB", "id": "F1NJ66", "url": "https://www.uniprot.org/uniprotkb/F1NJ66" } ], "pmid": "" }, { "name": "heart development", "id": "GO:0007507", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007507", "evidence": [ { "database": "UniProtKB", "id": "F1NJ66", "url": "https://www.uniprot.org/uniprotkb/F1NJ66" } ], "pmid": "" }, { "name": "embryonic organ morphogenesis", "id": "GO:0048562", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048562", "evidence": [ { "database": "UniProtKB", "id": "F1NJ66", "url": "https://www.uniprot.org/uniprotkb/F1NJ66" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "cohesin loader activity", "id": "GO:0061775", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061775", "evidence": [ { "database": "UniProtKB", "id": "F1NJ66", "url": "https://www.uniprot.org/uniprotkb/F1NJ66" } ], "pmid": "" }, { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "F1NJ66", "url": "https://www.uniprot.org/uniprotkb/F1NJ66" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "Scc2-Scc4 cohesin loading complex", "id": "GO:0090694", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090694", "evidence": [ { "database": "UniProtKB", "id": "F1NJ66", "url": "https://www.uniprot.org/uniprotkb/F1NJ66" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1NJ66", "url": "https://www.uniprot.org/uniprotkb/F1NJ66" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1006, "end_pos": 1008, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1067, "end_pos": 1069, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1121, "end_pos": 1123, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1260, "end_pos": 1262, "annotation": "n_glycosylation_sequon" }, { "start_pos": 128, "end_pos": 130, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1399, "end_pos": 1401, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1449, "end_pos": 1451, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1571, "end_pos": 1573, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1796, "end_pos": 1798, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1880, "end_pos": 1882, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1905, "end_pos": 1907, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2102, "end_pos": 2104, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2197, "end_pos": 2199, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2518, "end_pos": 2520, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2681, "end_pos": 2683, "annotation": "n_glycosylation_sequon" }, { "start_pos": 379, "end_pos": 381, "annotation": "n_glycosylation_sequon" }, { "start_pos": 437, "end_pos": 439, "annotation": "n_glycosylation_sequon" }, { "start_pos": 625, "end_pos": 627, "annotation": "n_glycosylation_sequon" }, { "start_pos": 668, "end_pos": 670, "annotation": "n_glycosylation_sequon" }, { "start_pos": 940, "end_pos": 942, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1NJ66", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NJ66" }, { "id": "PF12830", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12830" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Sister chromatid cohesion C-terminal", "eco_id": "ECO_0000259", "start_pos": 2248, "end_pos": 2428, "start_aa": "Ser", "end_aa": "Ile", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": 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"https://alphafold.ebi.ac.uk/entry/F1NSN0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000003420", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000003420", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd18329", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18329", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000210", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000210", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011333", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011333", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050457", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050457", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR46105", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46105", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46105:SF12", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46105:SF12", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00651", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00651", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YZF7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZF7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YZF7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZF7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z5I4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5I4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z5I4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5I4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z5I9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5I9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z5I9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5I9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NSN0", "url": "https://www.uniprot.org/uniprotkb/F1NSN0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NSN0-1", "url": "https://www.uniprot.org/uniprotkb/F1NSN0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRRKQPGRRIPSRTACGCERGRQRRLQGGQAEEAAGLCLQSVRCPFNCVPSPRASLSNAHVSKYLLFLSRSGFQGSGLRERGAERAPPGAGDSASSACPSIAAERAAAARGTPAGPHVCFGMEISSHQFHLLEQLNEQRRQDLFCDCNILVEGKVFKAHRNVLFASSGYFKMLLSQSSKEMTQPTTATFQAFSPDTFTVILDFVYSGKLSLTGQNVIEVMSAASYLQMTDVISVCKTFIKSSLDISEKEKDRYFSLSDKEVNSNGGEQPCLYSAGWRAESSPPHSHSNPDQGTCMRGNVWSNFNYYPASQRSTQQQPSKHDQRQDSIKKSRHPGLQQPSDIPHYKSSKLEDRAAEPAGHISQSEDQVQVEAEVESPHVGYQYGQGSDVISRSLAVPQQERDSPRPSSKSKSPKADEQYPSMPSIVGVMGGWAEDDLPRMRFKCPFCTHMVKRKADLKRHLRCHTGERPYPCEACGKRFSRLDHLSSHFRTIHQACKLICRKCKRHVTELTGQVVQEGTRRYRLCNECLAEAGIDSIRIDLEAEAPLEFPPDGDKDSRWHYGEDNKSDVEIVEDGSSDLVIQQVDDSEDEAEEKEVKPNIR", "length": 600, "header": "tr|F1NSN0-1|F1NSN0_CHICK Isoform 1 of Zinc finger and BTB domain containing 8A OS=Gallus gallus OX=9031 GN=ZBTB8A PE=4 SV=4 CANONICAL=F1NSN0-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YZF7-1", "url": "https://www.uniprot.org/uniprotkb/F1NSN0/entry#A0A8V0YZF7-1", "sequence": { "sequence": "MRRKQPGRRIPSRTACGCERGRQRRLQGGQAEEAAGLCLQSGSGLRERGAERAPPGAGDSASSACPSIAAERAAAARGTPAGPHVCFGMEISSHQFHLLEQLNEQRRQDLFCDCNILVEGKVFKAHRNVLFASSGYFKMLLSQSSKEMTQPTTATFQAFSPDTFTVILDFVYSGKLSLTGQNVIEVMSAASYLQMTDVISVCKTFIKSSLDISEKEKDRYFSLSDKEVNSNGGEQPCLYSAGWRAESSPPHSHSNPDQGTCMRGNVWSNFNYYPASQRSTQQQPSKHDQRQDSIKKSRHPGLQQPSDIPHYKSSKLEDRAAEPAGHISQSEDQVQVEAEVESPHVGYQYGQGSDVISRSLAVPQQERDSPRPSSKSKSPKADEQYPSMPSIVGVMGGWAEDDLPRMRFKCPFCTHMVKRKADLKRHLRCHTGERPYPCEACGKRFSRLDHLSSHFRTIHQACKLICRKCKRHVTELTGQVVQEGTRRYRLCNECLAEAGIDSIRIDLEAEAPLEFPPDGDKDSRWHYGEDNKSDVEIVEDGSSDLVIQQVDDSEDEAEEKEVKPNIR", "length": 567, "header": "tr|A0A8V0YZF7-1|A0A8V0YZF7_CHICK Computationally mapped isoform of Zinc finger and BTB domain containing 8A OS=Gallus gallus OX=9031 GN=ZBTB8A PE=4 SV=1 CANONICAL=F1NSN0-1" }, "locus": { "chromosome": "23", "start_pos": 5577899, "end_pos": 5573940, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044351.1", "url": "https://www.ensembl.org/id/ENSGALT00010044351.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026391.1", "url": "https://www.ensembl.org/id/ENSGALP00010026391.1" } ] } }, { "isoform_ac": "A0A8V0Z5I4-1", "url": "https://www.uniprot.org/uniprotkb/F1NSN0/entry#A0A8V0Z5I4-1", "sequence": { "sequence": "MRGRRYLNGPHVCFGMEISSHQFHLLEQLNEQRRQDLFCDCNILVEGKVFKAHRNVLFASSGYFKMLLSQSSKEMTQPTTATFQAFSPDTFTVILDFVYSGKLSLTGQNVIEVMSAASYLQMTDVISVCKTFIKSSLDISEKEKDRYFSLSDKEVNSNGGEQPCLYSAGWRAESSPPHSHSNPDQGTCMRGNVWSNFNYYPASQRSTQQQPSKHDQRQDSIKKSRHPGLQQPSDIPHYKSSKLEDRAAEPAGHISQSEDQVQVEAEVESPHVGYQYGQGSDVISRSLAVPQQERDSPRPSSKSKSPKADEQYPSMPSIVGVMGGWAEDDLPRMRFKCPFCTHMVKRKADLKRHLRCHTGERPYPCEACGKRFSRLDHLSSHFRTIHQACKLICRKCKRHVTELTGQVVQEGTRRYRLCNECLAEAGIDSIRIDLEAEAPLEFPPDGDKDSRWHYGEDNKSDVEIVEDGSSDLVIQQVDDSEDEAEEKEVKPNIR", "length": 494, "header": "tr|A0A8V0Z5I4-1|A0A8V0Z5I4_CHICK Computationally mapped isoform of Zinc finger and BTB domain containing 8A OS=Gallus gallus OX=9031 GN=ZBTB8A PE=4 SV=1 CANONICAL=F1NSN0-1" }, "locus": { "chromosome": "23", "start_pos": 5577899, "end_pos": 5575275, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044347.1", "url": "https://www.ensembl.org/id/ENSGALT00010044347.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026388.1", "url": "https://www.ensembl.org/id/ENSGALP00010026388.1" } ] } }, { "isoform_ac": "A0A8V0Z5I9-1", "url": "https://www.uniprot.org/uniprotkb/F1NSN0/entry#A0A8V0Z5I9-1", "sequence": { "sequence": "MGSGLRERGAERAPPGAGDSASSACPSIAAERAAAARGTPAGPHVCFGMEISSHQFHLLEQLNEQRRQDLFCDCNILVEGKVFKAHRNVLFASSGYFKMLLSQSSKEMTQPTTATFQAFSPDTFTVILDFVYSGKLSLTGQNVIEVMSAASYLQMTDVISVCKTFIKSSLDISEKEKDRYFSLSDKEVNSNGGEQPCLYSAGWRAESSPPHSHSNPDQGTCMRGNVWSNFNYYPASQRSTQQQPSKHDQRQDSIKKSRHPGLQQPSDIPHYKSSKLEDRAAEPAGHISQSEDQVQVEAEVESPHVGYQYGQGSDVISRSLAVPQQERDSPRPSSKSKSPKADEQYPSMPSIVGVMGGWAEDDLPRMRFKCPFCTHMVKRKADLKRHLRCHTGERPYPCEACGKRFSRLDHLSSHFRTIHQACKLICRKCKRHVTELTGQVVQEGTRRYRLCNECLAEAGIDSIRIDLEAEAPLEFPPDGDKDSRWHYGEDNKSDVEIVEDGSSDLVIQQVDDSEDEAEEKEVKPNIR", "length": 527, "header": "tr|A0A8V0Z5I9-1|A0A8V0Z5I9_CHICK Computationally mapped isoform of Zinc finger and BTB domain containing 8A OS=Gallus gallus OX=9031 GN=ZBTB8A PE=4 SV=1 CANONICAL=F1NSN0-1" }, "locus": { "chromosome": "23", "start_pos": 5577899, "end_pos": 5572989, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044354.1", "url": "https://www.ensembl.org/id/ENSGALT00010044354.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026393.1", "url": "https://www.ensembl.org/id/ENSGALP00010026393.1" } ] } }, { "isoform_ac": "F1NSN0-1", "url": "https://www.uniprot.org/uniprotkb/F1NSN0/entry#F1NSN0-1", "sequence": { "sequence": "MRRKQPGRRIPSRTACGCERGRQRRLQGGQAEEAAGLCLQSVRCPFNCVPSPRASLSNAHVSKYLLFLSRSGFQGSGLRERGAERAPPGAGDSASSACPSIAAERAAAARGTPAGPHVCFGMEISSHQFHLLEQLNEQRRQDLFCDCNILVEGKVFKAHRNVLFASSGYFKMLLSQSSKEMTQPTTATFQAFSPDTFTVILDFVYSGKLSLTGQNVIEVMSAASYLQMTDVISVCKTFIKSSLDISEKEKDRYFSLSDKEVNSNGGEQPCLYSAGWRAESSPPHSHSNPDQGTCMRGNVWSNFNYYPASQRSTQQQPSKHDQRQDSIKKSRHPGLQQPSDIPHYKSSKLEDRAAEPAGHISQSEDQVQVEAEVESPHVGYQYGQGSDVISRSLAVPQQERDSPRPSSKSKSPKADEQYPSMPSIVGVMGGWAEDDLPRMRFKCPFCTHMVKRKADLKRHLRCHTGERPYPCEACGKRFSRLDHLSSHFRTIHQACKLICRKCKRHVTELTGQVVQEGTRRYRLCNECLAEAGIDSIRIDLEAEAPLEFPPDGDKDSRWHYGEDNKSDVEIVEDGSSDLVIQQVDDSEDEAEEKEVKPNIR", "length": 600, "header": "tr|F1NSN0-1|F1NSN0_CHICK Isoform 1 of Zinc finger and BTB domain containing 8A OS=Gallus gallus OX=9031 GN=ZBTB8A PE=4 SV=4 CANONICAL=F1NSN0-1" }, "locus": { "chromosome": "23", "start_pos": 5577899, "end_pos": 5573940, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044348.1", "url": "https://www.ensembl.org/id/ENSGALT00010044348.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026389.1", "url": "https://www.ensembl.org/id/ENSGALP00010026389.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 7, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "F1NSN0", "url": "https://www.uniprot.org/uniprotkb/F1NSN0" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "F1NSN0", "url": "https://www.uniprot.org/uniprotkb/F1NSN0" } ], "pmid": "" }, { "name": "DNA-binding transcription repressor activity, RNA polymerase II-specific", "id": "GO:0001227", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001227", "evidence": [ { "database": "UniProtKB", "id": "F1NSN0", "url": "https://www.uniprot.org/uniprotkb/F1NSN0" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "F1NSN0", "url": "https://www.uniprot.org/uniprotkb/F1NSN0" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "F1NSN0", "url": "https://www.uniprot.org/uniprotkb/F1NSN0" } ], "pmid": "" }, { "name": "transcription coactivator binding", "id": "GO:0001223", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001223", "evidence": [ { "database": "UniProtKB", "id": "F1NSN0", "url": "https://www.uniprot.org/uniprotkb/F1NSN0" } ], "pmid": "" }, { "name": "RNA polymerase II-specific DNA-binding transcription factor binding", "id": "GO:0061629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061629", "evidence": [ { "database": "UniProtKB", "id": "F1NSN0", "url": "https://www.uniprot.org/uniprotkb/F1NSN0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1NSN0", "url": "https://www.uniprot.org/uniprotkb/F1NSN0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "F1NSN0", "url": "https://www.uniprot.org/uniprotkb/F1NSN0" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "F1NSN0", "url": "https://www.uniprot.org/uniprotkb/F1NSN0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 564, "end_pos": 566, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1NSN0-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 600, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1NSN0-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1NSN0" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 564, "end_pos": 566 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1NZK8-1", "uniprot_ac": "F1NZK8", "uniprot_id": "F1NZK8_CHICK", "mass": { "chemical_mass": 126646.0, "monoisotopic_mass": 126646.0 }, "refseq": { "ac": "NP_001034345", "name": "elongation factor-like GTPase 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001034345" }, "gene_names": [ { "name": "EFL1", "type": "recommended", "evidence": [ { "id": "F1NZK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NZK8" } ] }, { "name": "EFL1", "type": "synonym", "evidence": [ { "id": "NP_001034345", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001034345" } ] }, { "name": "EFTUD1", "type": "synonym", "evidence": [ { "id": "NP_001034345", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001034345" } ] } ], "protein_names": [ { "name": "Elongation factor-like GTPase 1", "type": "recommended", "evidence": [ { "id": "F1NZK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NZK8/entry#names_and_taxonomy" } ] }, { "name": "Elongation factor Tu GTP-binding domain-containing protein 1", "type": "synonym", "evidence": [ { "id": "F1NZK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NZK8/entry#names_and_taxonomy" } ] }, { "name": "Elongation factor-like 1", "type": "synonym", "evidence": [ { "id": "F1NZK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NZK8/entry#names_and_taxonomy" } ] }, { "name": "Protein FAM42A", "type": "synonym", "evidence": [ { "id": "F1NZK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NZK8/entry#names_and_taxonomy" } ] }, { "name": "elongation factor Tu GTP binding domain containing 1", "type": "synonym", "evidence": [ { "id": "NP_001034345", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001034345" } ] }, { "name": "elongation factor Tu GTP-binding domain-containing protein 1", "type": "synonym", "evidence": [ { "id": "NP_001034345", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001034345" } ] }, { "name": "elongation factor-like GTPase 1", "type": "synonym", "evidence": [ { "id": "NP_001034345", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001034345" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ851470.1, SRR13267659.101581.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000245.1. On Sep 23, 2021 this sequence version replaced NP_001034345.2. Sequence Note: This RefSeq record was created from transcript data from different strains because no single transcript from the same strain was available for the full length of the gene. The extent of this transcript is supported by transcript alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001034345", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001034345" } ] }, { "annotation": "GTPase involved in the biogenesis of the 60S ribosomal subunit and translational activation of ribosomes. Together with SBDS, triggers the GTP-dependent release of EIF6 from 60S pre-ribosomes in the cytoplasm, thereby activating ribosomes for translation competence by allowing 80S ribosome assembly and facilitating EIF6 recycling to the nucleus, where it is required for 60S rRNA processing and nuclear export.", "evidence": [ { "database": "UniProtKB", "id": "F1NZK8", "url": "https://www.uniprot.org/uniprotkb/F1NZK8#function" }, { "database": "UniProtKB", "id": "ARBA00054932", "url": "https://www.uniprot.org/uniprotkb/ARBA00054932#function" }, { "database": "UniProtKB", "id": "A0A8V0Z083", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z083#function" }, { "database": "UniProtKB", "id": "A0A8V0Z089", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z089#function" }, { "database": "UniProtKB", "id": "A0A8V0Z5N0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5N0#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NZK8", "url": "https://www.uniprot.org/uniprotkb/F1NZK8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "EFL1", "url": "https://www.uniprot.org/uniprotkb/F1NZK8", "locus": { "chromosome": "10", "start_pos": 11746252, "end_pos": 11690242, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010016921", "url": "https://www.ensembl.org/id/ENSGALG00010016921" } ] } } ], "crossref": [ { "id": "F1NZK8", "url": "https://alphafold.ebi.ac.uk/entry/F1NZK8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000006225", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000006225", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd01681", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01681", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd01885", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01885", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd04096", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04096", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd16261", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16261", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd16268", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16268", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "415467", "url": "https://www.ncbi.nlm.nih.gov/gene/415467", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000640", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000640", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000795", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000795", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005225", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005225", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009000", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009000", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014721", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014721", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020568", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020568", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035647", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035647", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041095", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041095", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056752", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056752", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:415467", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:415467", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "FARCDIQ", "url": "https://omabrowser.org/oma/group/FARCDIQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z083", "url": "https://www.orthodb.org/?gene=A0A8V0Z083", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z089", "url": "https://www.orthodb.org/?gene=A0A8V0Z089", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z5N0", "url": "https://www.orthodb.org/?gene=A0A8V0Z5N0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z5P9", "url": "https://www.orthodb.org/?gene=A0A8V0Z5P9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NZK8", "url": "https://www.orthodb.org/?gene=F1NZK8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR42908", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR42908", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR42908:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR42908:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00009", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00009", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00679", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00679", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14492", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14492", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25118", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25118", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001034345", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001034345", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "19669", "url": "https://www.rhea-db.org/rhea/19669", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0Z083", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z083", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z083-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z083-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z089", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z089", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z089-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z089-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z5N0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5N0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z5N0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5N0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z5P9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5P9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z5P9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5P9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NZK8", "url": "https://www.uniprot.org/uniprotkb/F1NZK8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NZK8-1", "url": "https://www.uniprot.org/uniprotkb/F1NZK8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVLTSVGKMMGLQQKAAGIRNICVLAHVDHGKTTLADCLISSNGIISSRLAGKLRYLDSREDEQVRGITMKSSAISLHFEKGGQEYLINLIDSPGHVDFSSEVSTAVRLCDGCIIVVDAVEGVCPQTQAVLRQAWLENIRPVLVINKIDRLIVELKLTPQEAYMHLKNILEQINAVTGSLFTSKVLEERAEKEAESESSSDTAAGDQIYDWSAGLEDTDDSHLYFSPDHGNVVFASAIDGWGFGIEHFAKLYSQKIGIKPAVLLKTLWGDYYLNTKAKKIMKGDQSKGKKPLFVQLVLDNIWSLYEAVMKRDKEKIEKIVTSLGLKIGPRESRHADPKVHLNAICSQWLPISDAVLSMVCSKLPSPLDITAERVEKLMCVGAKTFDSLPPETQELKSAFLRCSSEETAPVIVFVSKMFAVDAKALPHNKPRPLTQEEIAQRRELAKQRHAGKMAANQGKEVSEKPPSENSSEGTGSTGDKKGEEQQLTDQMDVVTSKAAKQEADNKESFIAFARVFSGVVRRGQKIFVLGPKYDPAESLHKLSPQCSATDDLPSVPHMSCCTLENLYLLMGRELEELEEVPAGNVLGIGGLQDFVLKSATLSTSPACPPFTPLNFEATPIVRVAVEPKHPSDMPQLVRGMKLLNQADPCVQVLIQETGEHVLVTAGEVHLQRCLDDLKERFAKIEISVSAPIIPFRETITRPPKVDMVNEEIGKQQKVAVIHQTKEDQNKIPEGIQVDSDGLVTISTPNKQATLSVRALPLPEEVTRLLEENSDLIRTMEQLSTSLNEDKNAHEINQKTMDKIKEFKQKLEQNLQGRKWRNAVDHIWSFGPRKCGPNILLHKFEGYKNSVWQCLENTEKEVSKYGDFDNSIVSGFQLATLSGPMCEEPLMGVCFTVEKWEMNKVGETLLTKSRDSGECGAVEHQESEDTVSPTSNCTVDTCSENEHEQSSQSVPKSLEKNSKNKGEVLLTDCYGPFSGQLIATMKEACRYALQAKPQRLMAAMYTCEIMATAEVLGRVYAVLSKREGRVLQEEMKEGTDVFIIKAVLPVAESFGFADEIRKRTSGLASPQLVFSHWEIISSDPFWVPTTEEEYLHFGEKADSENQARKYMNAVRKRKGLYVEEKIVEHAEKQRTLSRNK", "length": 1139, "header": "tr|F1NZK8-1|F1NZK8_CHICK Isoform 1 of Elongation factor-like GTPase 1 OS=Gallus gallus OX=9031 GN=EFL1 PE=1 SV=2 CANONICAL=F1NZK8-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z083-1", "url": "https://www.uniprot.org/uniprotkb/F1NZK8/entry#A0A8V0Z083-1", "sequence": { "sequence": "MLCRKSEEQQLTDQMDVVTSKAAKQEADNKESFIAFARVFSGVVRRGQKIFVLGPKYDPAESLHKLSPQCSATDDLPSVPHMSCCTLENLYLLMGRELEELEEVPAGNVLGIGGLQDFVLKSATLSTSPACPPFTPLNFEATPIVRVAVEPKHPSDMPQLVRGMKLLNQADPCVQVLIQETGEHVLVTAGEVHLQRCLDDLKERFAKIEISVSAPIIPFRETITRPPKVDMVNEEIGKQQKVAVIHQTKEDQNKIPEGIQVDSDGLVTISTPNKQATLSVRALPLPEEVTRLLEENSDLIRTMEQLSTSLNEDKNAHEINQKTMDKIKEFKQKLEQNLQGRKWRNAVDHIWSFGPRKCGPNILLHKFEGYKNSVWQCLENTEKEVSKYGDFDNSIVSGFQLATLSGPMCEEPLMGVCFTVEKWEMNKVGETLLTKSRDSGECGAVEHQESEDTVSPTSNCTVDTCSENEHEQSSQSVPKSLEKNSKNKGEVLLTDCYGPFSGQLIATMKEACRYALQAKPQRLMAAMYTCEIMATAEVLGRVYAVLSKREGRVLQEEMKEGTDVFIIKAVLPVAESFGFADEIRKRTSGLASPQLVFSHWEIISSDPFWVPTTEEEYLHFGEKADSENQARKYMNAVRKRKGLYVEEKIVEHAEKQRTLSRNK", "length": 663, "header": "tr|A0A8V0Z083-1|A0A8V0Z083_CHICK Computationally mapped isoform of Elongation factor-like GTPase 1 OS=Gallus gallus OX=9031 GN=EFL1 PE=1 SV=1 CANONICAL=F1NZK8-1" }, "locus": { "chromosome": "10", "start_pos": 11745896, "end_pos": 11707769, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010040848.1", "url": "https://www.ensembl.org/id/ENSGALT00010040848.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023812.1", "url": "https://www.ensembl.org/id/ENSGALP00010023812.1" } ] } }, { "isoform_ac": "A0A8V0Z089-1", "url": "https://www.uniprot.org/uniprotkb/F1NZK8/entry#A0A8V0Z089-1", "sequence": { "sequence": "MFSWTFLRCSSEETAPVIVFVSKMFAVDAKALPHNKPRPLTQEEIAQRRELAKQRHAGKMAANQGKEVSEKPPSENSSEGTGSTGDKKGEEQQLTDQMDVVTSKAAKQEADNKESFIAFARVFSGVVRRGQKIFVLGPKYDPAESLHKLSPQCSATDDLPSVPHMSCCTLENLYLLMGRELEELEEVPAGNVLGIGGLQDFVLKSATLSTSPACPPFTPLNFEATPIVRVAVEPKHPSDMPQLVRGMKLLNQADPCVQVLIQETGEHVLVTAGEVHLQRCLDDLKERFAKIEISVSAPIIPFRETITRPPKVDMVNEEIGKQQKVAVIHQTKEDQNKIPEGIQVDSDGLVTISTPNKQATLSVRALPLPEEVTRLLEENSDLIRTMEQLSTSLNEDKNAHEINQKTMDKIKEFKQKLEQNLQGRKWRNAVDHIWSFGPRKCGPNILLHKFEGYKNSVWQCLENTEKEVSKYGDFDNSIVSGFQLATLSGPMCEEPLMGVCFTVEKWEMNKVGETLLTKSRDSGECGAVEHQESEDTVSPTSNCTVDTCSENEHEQSSQSVPKSLEKNSKNKGEVLLTDCYGPFSGQLIATMKEACRYALQAKPQRLMAAMYTCEIMATAEVLGRVYAVLSKREGRVLQEEMKEGTDVFIIKAVLPVAESFGFADEIRKRTSGLASPQLVFSHWEIISSDPFWVPTTEEEYLHFGEKADSENQARKYMNAVRKRKGLYVEEKIVEHAEKQRTLSRNK", "length": 746, "header": "tr|A0A8V0Z089-1|A0A8V0Z089_CHICK Computationally mapped isoform of Elongation factor-like GTPase 1 OS=Gallus gallus OX=9031 GN=EFL1 PE=1 SV=1 CANONICAL=F1NZK8-1" }, "locus": { "chromosome": "10", "start_pos": 11745896, "end_pos": 11698810, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010040853.1", "url": "https://www.ensembl.org/id/ENSGALT00010040853.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023817.1", "url": "https://www.ensembl.org/id/ENSGALP00010023817.1" } ] } }, { "isoform_ac": "A0A8V0Z5N0-1", "url": "https://www.uniprot.org/uniprotkb/F1NZK8/entry#A0A8V0Z5N0-1", "sequence": { "sequence": "MPLTQEEIAQRRELAKQRHAGKMAANQGKEVSEKPPSENSSEGTGSTGDKKGEEQQLTDQMDVVTSKAAKQEADNKESFIAFARVFSGVVRRGQKIFVLGPKYDPAESLHKLSPQCSATDDLPSVPHMSCCTLENLYLLMGRELEELEEVPAGNVLGIGGLQDFVLKSATLSTSPACPPFTPLNFEATPIVRVAVEPKHPSDMPQLVRGMKLLNQADPCVQVLIQETGEHVLVTAGEVHLQRCLDDLKERFAKIEISVSAPIIPFRETITRPPKVDMVNEEIGKQQKVAVIHQTKEDQNKIPEGIQVDSDGLVTISTPNKQATLSVRALPLPEEVTRLLEENSDLIRTMEQLSTSLNEDKNAHEINQKTMDKIKEFKQKLEQNLQGRKWRNAVDHIWSFGPRKCGPNILLHKFEGYKNSVWQCLENTEKEVSKYGDFDNSIVSGFQLATLSGPMCEEPLMGVCFTVEKWEMNKVGETLLTKSRDSGECGAVEHQESEDTVSPTSNCTVDTCSENEHEQSSQSVPKSLEKNSKNKGEVLLTDCYGPFSGQLIATMKEACRYALQAKPQRLMAAMYTCEIMATAEVLGRVYAVLSKREGRVLQEEMKEGTDVFIIKAVLPVAESFGFADEIRKRTSGLASPQLVFSHWEIISSDPFWVPTTEEEYLHFGEKADSENQARKYMNAVRKRKGLYVEEKIVEHAEKQRTLSRNK", "length": 709, "header": "tr|A0A8V0Z5N0-1|A0A8V0Z5N0_CHICK Computationally mapped isoform of Elongation factor-like GTPase 1 OS=Gallus gallus OX=9031 GN=EFL1 PE=1 SV=1 CANONICAL=F1NZK8-1" }, "locus": { "chromosome": "10", "start_pos": 11745896, "end_pos": 11700931, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010040851.1", "url": "https://www.ensembl.org/id/ENSGALT00010040851.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023815.1", "url": "https://www.ensembl.org/id/ENSGALP00010023815.1" } ] } }, { "isoform_ac": "A0A8V0Z5P9-1", "url": "https://www.uniprot.org/uniprotkb/F1NZK8/entry#A0A8V0Z5P9-1", "sequence": { "sequence": "MVLTSVGKMMGLQQKAAGIRNICVLAHVDHGKTTLADCLISSNGIISSRLAGKLRYLDSREDEQVRGITMKSSAISLHFEKGGQEYLINLIDSPGHVDFSSEVSTAVRLCDGCIIVVDAVEGVCPQTQAVLRQAWLENIRPVLVINKIDRLIVELKLTPQEAYMHLKNILEQINAVTGSLFTSKVLEERAEKEAESESSSDTAAGDQIYDWSAGLEDTDDSHLYFSPDHGNVVFASAIDGWGFGIEHFAKLYSQKIGIKPAVLLKTLWGDYYLNTKAKKIMKGDQSKGKKPLFVQLVLDNIWSLYEAVMKRDKEKIEKIVTSLGLKIGPRESRHADPKVHLNAICSQWLPISDAVLSMVCSKLPSPLDITAERVEKLMCVGAKTFDSLPPETQELKSAFLRCSSEETAPVIVFVSKMFAVDAKALPHNKPRPLTQEEIAQRRELAKQRHAGKMAANQGKEVSEKPPSENSSEGTGSTGDKKGEEQQLTDQMDVVTSKAAKQEADNKESFIAFARVFSGVVRRGQKIFVLGPKYDPAESLHKLSPQCSATDDLPSVPHMSCCTLENLYLLMGRELEELEEVPAGNVLGIGGLQDFVLKSATLSTSPACPPFTPLNFEATPIVRVAVEPKHPSDMPQLVRGMKLLNQADPCVQVLIQETGEHVLVTAGEVHLQRCLDDLKERFAKIEISVSAPIIPFRETITRPPKVDMVNEEIGKQQKVAVIHQTKEDQNKIPEGIQVDSDGLVTISTPNKQATLSVRALPLPEEVTRLLEENSDLIRTMEQLSTSLNEDKNAHEINQKTMDKIKEFKQKLEQNLQGRKWRNAVDHIWSFGPRKCGPNILLHKFEGYKNSVWQCLENTEKELIATMKEACRYALQAKPQRLMAAMYTCEIMATAEVLGRVYAVLSKREGRVLQEEMKEGTDVFIIKAVLPVAESFGFADEIRKRTSGLASPQLVFSHWEIISSDPFWVPTTEEEYLHFGEKADSENQARKYMNAVRKRKGLYVEEKIVEHAEKQRTLSRNK", "length": 1020, "header": "tr|A0A8V0Z5P9-1|A0A8V0Z5P9_CHICK Computationally mapped isoform of Elongation factor-like 1 OS=Gallus gallus OX=9031 GN=EFL1 PE=1 SV=1 CANONICAL=F1NZK8-1" }, "locus": { "chromosome": "10", "start_pos": 11745896, "end_pos": 11690518, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010040866.1", "url": "https://www.ensembl.org/id/ENSGALT00010040866.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023830.1", "url": "https://www.ensembl.org/id/ENSGALP00010023830.1" } ] } }, { "isoform_ac": "F1NZK8-1", "url": "https://www.uniprot.org/uniprotkb/F1NZK8/entry#F1NZK8-1", "sequence": { "sequence": "MVLTSVGKMMGLQQKAAGIRNICVLAHVDHGKTTLADCLISSNGIISSRLAGKLRYLDSREDEQVRGITMKSSAISLHFEKGGQEYLINLIDSPGHVDFSSEVSTAVRLCDGCIIVVDAVEGVCPQTQAVLRQAWLENIRPVLVINKIDRLIVELKLTPQEAYMHLKNILEQINAVTGSLFTSKVLEERAEKEAESESSSDTAAGDQIYDWSAGLEDTDDSHLYFSPDHGNVVFASAIDGWGFGIEHFAKLYSQKIGIKPAVLLKTLWGDYYLNTKAKKIMKGDQSKGKKPLFVQLVLDNIWSLYEAVMKRDKEKIEKIVTSLGLKIGPRESRHADPKVHLNAICSQWLPISDAVLSMVCSKLPSPLDITAERVEKLMCVGAKTFDSLPPETQELKSAFLRCSSEETAPVIVFVSKMFAVDAKALPHNKPRPLTQEEIAQRRELAKQRHAGKMAANQGKEVSEKPPSENSSEGTGSTGDKKGEEQQLTDQMDVVTSKAAKQEADNKESFIAFARVFSGVVRRGQKIFVLGPKYDPAESLHKLSPQCSATDDLPSVPHMSCCTLENLYLLMGRELEELEEVPAGNVLGIGGLQDFVLKSATLSTSPACPPFTPLNFEATPIVRVAVEPKHPSDMPQLVRGMKLLNQADPCVQVLIQETGEHVLVTAGEVHLQRCLDDLKERFAKIEISVSAPIIPFRETITRPPKVDMVNEEIGKQQKVAVIHQTKEDQNKIPEGIQVDSDGLVTISTPNKQATLSVRALPLPEEVTRLLEENSDLIRTMEQLSTSLNEDKNAHEINQKTMDKIKEFKQKLEQNLQGRKWRNAVDHIWSFGPRKCGPNILLHKFEGYKNSVWQCLENTEKEVSKYGDFDNSIVSGFQLATLSGPMCEEPLMGVCFTVEKWEMNKVGETLLTKSRDSGECGAVEHQESEDTVSPTSNCTVDTCSENEHEQSSQSVPKSLEKNSKNKGEVLLTDCYGPFSGQLIATMKEACRYALQAKPQRLMAAMYTCEIMATAEVLGRVYAVLSKREGRVLQEEMKEGTDVFIIKAVLPVAESFGFADEIRKRTSGLASPQLVFSHWEIISSDPFWVPTTEEEYLHFGEKADSENQARKYMNAVRKRKGLYVEEKIVEHAEKQRTLSRNK", "length": 1139, "header": "tr|F1NZK8-1|F1NZK8_CHICK Isoform 1 of Elongation factor-like GTPase 1 OS=Gallus gallus OX=9031 GN=EFL1 PE=1 SV=2 CANONICAL=F1NZK8-1" }, "locus": { "chromosome": "10", "start_pos": 11745896, "end_pos": 11690518, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010040860.1", "url": "https://www.ensembl.org/id/ENSGALT00010040860.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023824.1", "url": "https://www.ensembl.org/id/ENSGALP00010023824.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:415467", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:415467", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287BT76-1", "protein_name": "Elongation factor-like GTPase 1", "gene_name": "EFL1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MVLNSLDKMIQLQKNTANIRNICVLAHVDHDDEEYLINLIDSPGHVDFSSEVSTAVRICDGCIIVVDAVEGVCPQTQAVLRQAWLENIRPVLVINKIDRLIVELKFTPQEAYSHLKNILEQINALTGTLFTSKVLEERAERVTESQVNPHSEQGEQVYDWSTGLEDTDDSHLYFSPDQGNVVFTSAIDGWGFGIEHFAKIYSQKTGIRKEVLLKTLWGDYYINMKAKKIMKVDQAKGKKPLFVQLILGNIWSLYDAVLKKDKEKIDKIVTSLGLKIGAREARHSDPKVQINAICSQWLPISQAVLAMVCQKLPSPLDITAERVEKLMCAGSQTFDSLPPETQALKAAFMKCGSEDTAPVIIFVSKMFAVDAKALPQNKPRPLTPEEIAERRERARRRHAEKLAAAQGQAPVEPTQDGSALEASPKEEEPKGDEQQVLQEGNDQESFIAFARVFSGVARRGKKIFVLGPKYSPLEFLQRVPLGFSAPLDGLPPVPHMACCTLENLYLLMGRELEDLEEVPPGNVLGIGGLQDFVLKSATLCTLPSCPPFIPLNFEATPIVRVAVEPKHPSEMPQLVKGMKLLNQADPCVQILIQETGEHVLVTAGEVHLQRCLDDLKERFAKIQISVSEPIIPFRETITKPPKVDMVNEEIGKQQKVAVIHQTKEDQSKIPEGIQVDSDGLVTITTPNKLATLCVRAMPLPEEVTQILEENSDLIRSMEQLTSSLNEGKNTQVIHQKTQEKIGEFKGRLEQHLTGRKWRNTVDQIWSFGPRKCGPNILVNKSEDFQNSVWTGPDGKASQEANRYRDLGNSIVSGFQLATLSGPMCEEPLMGVCFVLEKWDLSKFEEQTASDKQNQKQSDLVDAGQGEGETSSAGDENQEVHNGCSEPFEKRPSQKGESSLTDCYGPFSGQLIATMKEACRYALQVKPQRLMAAMYTCDIMATSDVLGRVYAVLSKREGRVLQEEMKEGTDMFIIKAVLPVAESFGFADEIRKRTSGLASPQLVFSHWEIIPSDPFWVPTTEEEYLHFGEKADSENQARKYMNAVRKRKGLYVEEKIVEHAEKQRTLSKNK", "length": 1069 }, "evidence": [ { "id": "F1NZK8", "url": "https://omabrowser.org/oma/group/F1NZK8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A9J7FRL8-1", "protein_name": "Elongation factor-like GTPase 1", "gene_name": "Efl1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MVLNGVDKMIQLQKHTANIRNICVLAHVDHGKTTLADCLISSNGIISSRLAGKLRYMDSREDEQVRGITMKSSAISLHYAEGNEEYLINLIDSPGHVDFSSEVSTAVRICDGCIIVVDAVEGVCPQTQAVLRQAWLENIRPVLVINKLDRLIVELKFTPQEAYSHLKNILEQINALTGTLFTSKVLEERAERETDSQVKTQSEQGDQVYDWSTGLEDADDSQLYFSPEQGNVVFTSAIDGWGFGIEHFARIYSQKIGIKKEVLLKTLWGDYYINMKAKKIMKVDQAKGKKPLFVQLILENIWSLYDAVLKKDKEKIDKIVTSLGLKIGAREARHSDPKVQINAICSQWLPISHAVLAMVCQKLPSPLDMTSERVEKLMCTGSQTFESLPLETQALKAAFMKCGSEDTAPVIIFVSKMFAVDAKTLPQNKPRPLTQEEIAQRRERARQRHAERLAGTQGQAPQGPTQDGGTLETGPQGDEPRGDEPDVASISPQPVAQEESSQEAFIAFARVFSGIARRGQKIFVLGPKYSPVEFLQRVPLGFSAPLEDLPPVPHMACCTLENLYLLMGRELEDLEEVPPGNVLGIGGLQDFVLKSATLCSLPSCPPFIPLNFEATPIVRVAVEPKHPSEMPQLVKGMKLLNQADPCVQILIQETGEHVLVTAGEVHLQRCLDDLRERFAKIHISVSEPIIPFRETITKPPKVDMVNEEIGRQQKVAVIHQTKEEQSKIPEGIHVDSDGLITITTPNKLATLSVRAIPLPEEVTQILEENSDLIRSMELLTSSLNEGRNTQGIHQKTQEKIWDFKGKLEQHLIGRKWRNTVDQIWSFGPRKCGPNILVSRSEDFQNSVWSGPAGKESKEASRFRDFGNSIVSGFQLATLSGPMCEEPLMGVCFVLEKWELNKCAEQGASDKQNQKQCDLAEEGQEEGKTCHSGDENQEQQDGCSEPFEETSPKGESPVTDCYGPFSGQLIATMKEACRYALQVKPQRLMAAMYTCDIMATSDVLGRVYAVLSKREGRVLQEEMKEGTDMFIIKAVLPVAESFGFADEVRKRTSGLASPQLVFSHWEVIPSDPFWVPTTEEEYLHFGEKADSENQARKYMNAVRKRKGLYVEEKIVEHAEKQRTLSKNK", "length": 1127 }, "evidence": [ { "id": "F1NZK8", "url": "https://omabrowser.org/oma/group/F1NZK8/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0AAA9SKN9-1", "protein_name": "Elongation factor-like GTPase 1", "gene_name": "EFL1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MVLNSLDKMIQLQKNTANIRNICVLAHVDHGDKEYLINLIDSPGHVDFSSEVSTAVRICDGCIIVVDAVEGVCPQTQAVLRQAWLENIRPVLVINKIDRLIVELKFTPQEAYSHLKNILEQINALTGTLFTSKVLEERAEREAESQVNPNSEQGEQVYDWSTGLEDTDDSHLYFSPDQGNVVFTSAIDGWGFGIEHFAKIYSQKTGIRKEVLLKTLWGDYYINTKAKKIMKVDQAKGKKPLFVQLILENIWSLYDAVLKKDKEKTDKIVTSLGLKIGAREARHSDPKVQINAICSQWLPISQAVLAMVCQKLPSPLDITAERVEKLMCAGSQTFDSLPPETQALKAAFMKCGSEDTAPVIIFVSKMFAVDAKALPQNKPRPLTQEEIAERRERARRRHAEKLAAAQGQAPVEPTQDAGALEMSPQGEEPKGDEQGVESETPKPVSPEGSEQESFIAFARVFSGVARKGKRIFVLGPKYSPLEFLQQVPLGFSAPLEDLPPVPHMACCTLENLYLLMGRELEDLEEVPPGNVLGIGGLQDFVLKSATLCTSPSCPPFIPLNFEATPIVRVAIEPKHPSEMPQLVKGMKLLNQADPCVQVFIQETGEHVLVTAGEVHLQRCLDDLKERFAKIEISVSEPIIPFRETITKPPKVDMVNEEIGKQQKVAVIHQTKEDQSKIPEGIQVDSNGLITMMTPNKLATLSVRALPLPEEVTQILEESSDLIRSMEQLTSSLNEGKNNPQMIHQKTQEKIWEFKGKLEHHLTGRKWRNTVDQIWSFGPRKCGPNILVNKSEDFHNSVWTGLDGKASKEASRYRDLGNSIVSGFQLATLSGPMCEEPLMGVCFVLEKWDLSKFEEQTASDLVKERQGEGDTRSGGDEQQELQDYGSEPFEKRASQRGESPLTDCYGPFSGQLIATMKEACRYALQVKPQRLMAAMYTCDIMATSDVLGRVYAVLSKREGRVLQEEMKEGTDMFIIKAVLPVAESFGFADEIRKRTSGLASPQLVFSHWEIIPSDPFWVPTTEEEYLHFGEKADSENQARKYMNAVRKRKGLYVEEKIVEHAEKQRTLSKNK", "length": 1070 }, "evidence": [ { "id": "F1NZK8", "url": "https://omabrowser.org/oma/group/F1NZK8/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "D3ZXJ5-1", "protein_name": "Elongation factor-like GTPase 1", "gene_name": "Efl1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVLSGLDKMIQLQKNTANIRNICVLAHVDHGKTTLADCLISSNGIISSRLAGKLRYMDSREDEQVRGITMKSSAISLHYAEGSEEYLINLIDSPGHVDFSSEVSTAVRICDGCIIVVDAVEGVCPQTQAVLRQAWLENIRPVLVINKIDRLIVELKFTPQEAYSHLKNILGQINALTGTLFTSKVLEERAERETESQAKSHSEQGDQVYDWSTGLEDVDDSQLYFSPEQGNVVFTSAIDGWGFGIEHFARIYSQKIGIKKEVLLKTLWGDYYINMKAKKIMKVDQAKGKKPLFVQLILENIWSLYDAVLKKDKEKVDKIVTSLGLKIGAREARHSDPKVQINAICSQWLPISHAVLAMVCQKLPSPLDMTSERVEKLMCTGSQTFESLPLETQALKAAFMKCGSEDTAPVIIFVSKMFAVDVKALPQNKPRPLTQEEMAQRRERARQRHAEKLAAAQGQAPQGPTQDGGALETSPQEDEPRGEEPDMTSVSRQPAPQEESSQEAFIAFARVFSGVARRGKKIFVLGPKYSPVDFLQRVPQGFSAPLEDLPPVPHMACCTLENLYLLMGRELEDLEEVPPGNVLGIGGLQDSVLKSATLCSLPSCPPFIPLNFEATPIVRVAVEPKHPSEMPQLVKGMKLLNQADPCVQILIQETGEHVLVTAGEVHLQRCLDDLRERFAKIHISVSEPIIPFRETITKPPKVDMVNEEIGRQQKVAVIHQTKEEQSKIPEGILVDSDGLITIPTPNKLATLSVRAIPLPEEVTRILEENSDLIRSMELLTSSLNEGRNTQAIHQKTQEKIWEFKGKLEKHLTGRKWRNTVDQIWSFGPRKCGPNILVSRSEDFQSSVWSGPAGRESKEASRFRDFGNSIVSGFQLATLSGPMCEEPLMGVCFVLEKWELNKCAEPGASDKQSQGQCDLTGEGQEKSKTCPVGDENQEQQDGYSEPFEETSQKGDSPVIDCYGPFSGQLIATMKEACRYALQVKPQRLMAAMYTCDIMATSDVLGRVYAVLSKREGRVLQEEMKEGTDMFIIKAVLPVAESFGFADEIRKRTSGLASPQLVFSHWEVIPSDPFWVPTTEEEYLHFGEKADSENQARKYMNAVRKRKGLYVEEKIVEHAEKQRTLSKNK", "length": 1127 }, "evidence": [ { "id": "F1NZK8", "url": "https://omabrowser.org/oma/group/F1NZK8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F4J2T9-1", "protein_name": "Elongation factor-like 1", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MDESEGRKVRNICILAHVDHGKTTLADHLIASSGGGVLHPRLAGKLRFMDYLDEEQRRAITMKSSSISLKYKDYSLNLIDSPGHMDFCSEVSTAARLSDGALVLVDAVEGVHIQTHAVLRQAWIEKLTPCLVLNKIDRLIFELRLSPMEAYTRLIRIVHEVNGIVSAYKSEKYLSDVDSILASPSGELSAESLELLEDDEEVTFQPQKGNVVFVCALDGWGFGIAEFANFYASKLGASATALQKSLWGPRYYIPKTKMIVGKKNLSAGSKAKPMFVQFVLEPLWQVYEAALDPGGDKAVLEKVIKSFNLSIPPRELQNKDPKNVLQSVMSRWLPLSDAVLSMAVKHLPDPIAAQAYRIPRLVPERKIIGGDDVDSSVLAEAELVRKSIEACDSSSDSPCVVFVSKMFAIPMKMIPQDGNHRERMNGLNDDDSKSESDECFLAFARIFSGVLRAGQRVFVITALYDPLKGESSHKYIQEAELHSLYLMMGQGLTPVTEVKAGNVVAIRGLGPYISKSATLSSTRNCWPLASMEFQVSPTLRVAIEPSDPADMSALMKGLRLLNRADPFVEITVSARGEHVLAAAGEVHLERCVKDLKERFAKVNLEVSPPLVSYRETIEGDGSNLLESLRSLSLNSSDYIEKRTPNGRCIIRVHVMKLPHALTKLLDENTELLGDIIGGKGSHSVKILESQKPSLGENVDPIEELKKQLVEAGVSSSSETEKDREKCKTEWSKLLKRIWALGPREKGPNILFAPDGKRIAEDGSMLVRGSPHVSQRLGFTEDSTETPAEVSETALYSEALTLESSIVSGFQLATASGPLCDEPMWGLAFTIESHLAPAEDVETDKPENFGIFTGQVMTAVKDACRAAVLQTNPRIVEAMYFCELNTAPEYLGPMYAVLSRRRARILKEEMQEGSSLFTVHAYVPVSESFGFADELRKGTSGGASALMVLSHWEMLEEDPFFVPKTEEEIEEFGDGASVLPNTARKLINAVRRRKGLHVEEKVVQYATKQRTLARKV", "length": 1015 }, "evidence": [ { "id": "F1NZK8", "url": "https://omabrowser.org/oma/group/F1NZK8/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "P53893-1", "protein_name": "Ribosome assembly protein 1", "gene_name": "RIA1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MPRVESETYKRLQNDPSCIRNICIVAHVDHGKTSLSDSLLASNGIISQRLAGKIRFLDARPDEQLRGITMESSAISLYFRVLRKQEGSDEPLVSEHLVNLIDSPGHIDFSSEVSAASRLCDGAVVLVDVVEGVCSQTVTVLRQCWTEKLKPILVLNKIDRLITELQLTPQEAYIHLSKVIEQVNSVIGSFFANERQLDDLFWREQLEKNENAEYIEKDDSGIYFNPTDNNVIFASAIDGWGFNIGQLAKFYEQKLGAKRENLQKVLWGDFYMDPKTKKIINNKGLKGRSLKPLFTSLILENIWKIYQNIITSRDSEMVEKIAKTLNIKLLARDLRSKDDKQLLRTIMGQWLPVSTAVLLTVIEKLPSPLESQTDRLNTILVSESDTAAMDPRLLKAMKTCDKEGPVSAYVSKMLSIPREELPVESKRIASSDELMERSRKAREEALNAAKHAGMVENMAMMDLNDNSKNTSDLYKRAKDTVMTPEVGEQTKPKPSRNNDVFCVVSEPSSALDLEFEYEGEDDSDSQDNFGLDFVPTDIDPNDPLSSMFEYEEEDPLLESIKQISEDVNDEVDDIFDEKEECLVAFARIYSGTLRVGQEISVLGPKYDPKCPEEHIETAIITHLYLFMGKELVPLDVCPSGNIVGIRGLAGKVLKSGTLIEKGVQGVNLAGVNFHFTPIVRVAVEPANPVEMSKLVRGLKLLDQADPCVHTYVENTGEHILCTAGELHLERCLKDLTERFAGIEITHSEPAIPYRETFLSASDMNPPQNSQLGRGVHELLLSQYKITFRTFPLSGKVTDFLSQHQNSIKNILKTSTSSMDPVIESTGSSFLDKKSLLVAFEEVINQEEKSRELLSGFKVKLAGFGPSRVGCNILLSQDNLLGSLFEGTPAAFEYSDSIKNGFQLAVSEGPLANEPVQGMCVLVESVHKMSQDEIESIEDPRYQQHIVDLSGRLITSTRDAIHEAFLDWSPRIMWAIYSCDIQTSVDVLGKVYAVILQRHGKIISEEMKEGTPFFQIEAHVPVVEAFGLSEDIRKRTSGAAQPQLVFSGFECIDLDPFWVPTTEEELEELGDTADRENIARKHMNAIRRRKGLFIEEKVVENAEKQRTLKKN", "length": 1110 }, "evidence": [ { "id": "F1NZK8", "url": "https://omabrowser.org/oma/group/F1NZK8/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q54WF2-1", "protein_name": "Ribosome assembly protein 1", "gene_name": "eftud1", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MPSISPNLLASLQDHTKNIRNICVLAHVDHGKTTLSDCLISSNGIISPEMAGKLRYLDFLEDEQEREITMKASAISLLFQQPSSSSSSNDKESFLINLIDSPGHVDFSSEVSTAVRITDGALVLVDAVEGVCIQTHAVLKQAYQEKVKPCLVLNKIDRLILELHMTPLEAYQHLSKIIEQVNVITGTLTSEEIILKESSEDYIESSDDSNLNFNENIGTEYYFSPQKGNVAFTTAFDGWGFTIKQFIDLCYKKTGIKKEILEKCLWGEYYYHPKEKKIYKSPKGNLMPMFVTFILNSVWEVVKTIVGTPEWIDRDRLDKMISVLNITVGARDLASKDQKIVLKSVLHAWLPLSEAVLSMVCDKLPDPIEGQARRMEKIFKPSKSLSTSSSSSSSSSNQSNVELIEKQKQLLYDTITCNSSDDCEIVAYVAKVFAHNKRGGVQTSTIHRPVPPRRVQPSAVPSQNRQQQLHQDEKDILKIDNMFISSAPSTTNDSTTTTKTTTTSPSSPITSTAKPLDLSTIPTGPIKANNNDEEFIAVVRVFSGVLKKGKTIYVMGPRYDPMNPTHDVYKVEITHLYLLMGSSLEPIDKVPAGNVCGVGGGVGNLVLKSATISSSLMCPPISNMMFVSSPIVKVALEPENISDLPKLLHGLKLLNQADPLVEVYVQETGEHVIVASGELHLERCIRDLKESFAKINVHVSSPIVPFRETIITPTITTPTTSSTITSSSSTTAAATATTTNNSGQQSPPLKEIITVKTANKKVSVKIRAIPLPKNITNLIEQRSQQLRDLFLGGKNTNKELSDNKITKREAEQAEREDFQKELEEELEKSGGDWKNEIKNIWSFGPRHIGPNLLLNHIPGYNLSPYWKHSLQRGIQKKLKKLQKQQQQEKEEIKEEEEEKEEEEKEDEEDEDEKEIEEEEIQEEENSNSEVGSIKLLDGDDKFKRISELDNSIVSGFQLATIAGPLCDEPMMGVCLIVEDIDIIREEGDQQNSDSYGPLSGQMISTVKEGCRMAFQIKPQRLMEALYLCEIQVTSTALGKMYSVLSSRRAQIQKEGVKEGTQIFCIQARLPVVESFGFSQQIMIKTSGAASTQLFFDNYWETIEQDPYYEPTTEEELEDNGVNIASLGNNIARQYMNMIRKRKGLFVEEKLVEHADKQRTLKKNK", "length": 1164 }, "evidence": [ { "id": "F1NZK8", "url": "https://omabrowser.org/oma/group/F1NZK8/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q7Z2Z2-1", "protein_name": "Elongation factor-like GTPase 1", "gene_name": "EFL1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVLNSLDKMIQLQKNTANIRNICVLAHVDHGKTTLADCLISSNGIISSRLAGKLRYMDSREDEQIRGITMKSSAISLHYATGNEEYLINLIDSPGHVDFSSEVSTAVRICDGCIIVVDAVEGVCPQTQAVLRQAWLENIRPVLVINKIDRLIVELKFTPQEAYSHLKNILEQINALTGTLFTSKVLEERAERETESQVNPNSEQGEQVYDWSTGLEDTDDSHLYFSPEQGNVVFTSAIDGWGFGIEHFARIYSQKIGIKKEVLMKTLWGDYYINMKAKKIMKGDQAKGKKPLFVQLILENIWSLYDAVLKKDKDKIDKIVTSLGLKIGAREARHSDPKVQINAICSQWLPISHAVLAMVCQKLPSPLDITAERVERLMCTGSQTFDSFPPETQALKAAFMKCGSEDTAPVIIFVSKMFAVDAKALPQNKPRPLTQEEIAQRRERARQRHAEKLAAAQGQAPLEPTQDGSAIETCPKGEEPRGDEQQVESMTPKPVLQEENNQESFIAFARVFSGVARRGKKIFVLGPKYSPLEFLRRVPLGFSAPPDGLPQVPHMAYCALENLYLLMGRELEYLEEVPPGNVLGIGGLQDFVLKSATLCSLPSCPPFIPLNFEATPIVRVAVEPKHPSEMPQLVKGMKLLNQADPCVQILIQETGEHVLVTAGEVHLQRCLDDLKERFAKIHISVSEPIIPFRETITKPPKVDMVNEEIGKQQKVAVIHQMKEDQSKIPEGIQVDSDGLITITTPNKLATLSVRAMPLPEEVTQILEENSDLIRSMEQLTSSLNEGENTHMIHQKTQEKIWEFKGKLEQHLTGRRWRNIVDQIWSFGPRKCGPNILVNKSEDFQNSVWTGPADKASKEASRYRDLGNSIVSGFQLATLSGPMCEEPLMGVCFVLEKWDLSKFEEQGASDLAKEGQEENETCSGGNENQELQDGCSEAFEKRTSQKGESPLTDCYGPFSGQLIATMKEACRYALQVKPQRLMAAMYTCDIMATGDVLGRVYAVLSKREGRVLQEEMKEGTDMFIIKAVLPVAESFGFADEIRKRTSGLASPQLVFSHWEIIPSDPFWVPTTEEEYLHFGEKADSENQARKYMNAVRKRKGLYVEEKIVEHAEKQRTLSKNK", "length": 1120 }, "evidence": [ { "id": "F1NZK8", "url": "https://omabrowser.org/oma/group/F1NZK8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8C0D5-1", "protein_name": "Elongation factor-like GTPase 1", "gene_name": "Efl1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVLSGVDKMIRLQKNTANIRNICVLAHVDHGKTTLADCLISSNGIISSRLAGKLRYMDSREDEQVRGITMKSSAISLHYAEGHEEYLINLIDSPGHVDFSSEVSTAVRICDGCIIVVDAVEGVCPQTQAVLRQAWLENIRPVLVINKIDRLIVELKFTPQEAYSHLKNILEQINALTGTLFTSKVLEERAERETESQAKPHSEQGEQVYDWSAGLEDVDDSQLYFSPEQGNVVFTSAIDGWGFGIEHFARIYSQKIGIKKEVLLKTLWGDYYINMKAKKIMKVDQAKGKKPLFVQLILENIWSLYDAVLKKDKEKIDKIVTSLGLKIGAREARHSDPKVQINAICSQWLPISHAVLAMVCHKLPSPLDMTSERVEKLLCTGSQTFESLPPETQALKAAFMKCGSEDTAPVIIFVSKMFAVDVKALPQNKPRPLTQEEMAQRRERARQRHAEKLAAAQGQTSQGPTQDGGALETSPHEDEPRGDEPDVASVSRQPVSQEESSQEAFIAFARVFSGIARRGKKIFVLGPKYSPVDFLQRVPLGFSAPLEDLPPVPHMACCTLENLYLLMGRELEDLEEVPPGNVLGIGGLQDFVLKSATLCSLPSCPPFIPLNFEATPIVRVAVEPKHPSEMPQLVKGMKLLNQADPCVQVLIQETGEHVLVTAGEVHLQRCLDDLRERFAKIHISVSEPIIPFRETITKPPKVDMVNEEIGRQQKVAVIHQTKEEQSKIPEGIHVDSDGLITIPTPNKLATLSVRAIPLPEEVTRILEENSDLIRSMELLTSSLNEGRNTQAIHQKTQEKIWEFKGKLEKHLTGRKWRNTVDQIWSFGPRKCGPNILVSRSEDFQNSVWSGPAGRESKEASRFRDFGNSIVSGFQLATLSGPMCEEPLMGVCFVLEKWELNKCAEQGASDKQHQGQCDLAGEGQGGGKTCHVGDENQEQQDVCSEPFEETSQKGDSPVIDCYGPFSGQLIATMKEACRYALQVKPQRLMAAMYTCDIMATSDVLGRVYAVLSKREGRVLQEEMKEGTDMFIIKAVLPVAESFGFADEIRKRTSGLASPQLVFSHWEVIPSDPFWVPTTEEEYLHFGEKADSENQARKYMNAVRKRKGLYVEEKIVEHAEKQRTLSKNK", "length": 1127 }, "evidence": [ { "id": "F1NZK8", "url": "https://omabrowser.org/oma/group/F1NZK8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "GTPase activity", "id": "GO:0003924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003924", "evidence": [ { "database": "UniProtKB", "id": "F1NZK8", "url": "https://www.uniprot.org/uniprotkb/F1NZK8" } ], "pmid": "" }, { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "F1NZK8", "url": "https://www.uniprot.org/uniprotkb/F1NZK8" } ], "pmid": "" }, { "name": "translation elongation factor activity", "id": "GO:0003746", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003746", "evidence": [ { "database": "UniProtKB", "id": "F1NZK8", "url": "https://www.uniprot.org/uniprotkb/F1NZK8" } ], "pmid": "" }, { "name": "ribosome binding", "id": "GO:0043022", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043022", "evidence": [ { "database": "UniProtKB", "id": "F1NZK8", "url": "https://www.uniprot.org/uniprotkb/F1NZK8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "cytosolic ribosome assembly", "id": "GO:0042256", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042256", "evidence": [ { "database": "UniProtKB", "id": "F1NZK8", "url": "https://www.uniprot.org/uniprotkb/F1NZK8" } ], "pmid": "" }, { "name": "GTP metabolic process", "id": "GO:0046039", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046039", "evidence": [ { "database": "UniProtKB", "id": "F1NZK8", "url": "https://www.uniprot.org/uniprotkb/F1NZK8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F1NZK8", "url": "https://www.uniprot.org/uniprotkb/F1NZK8" } ], "pmid": "" }, { "name": "ribonucleoprotein complex", "id": "GO:1990904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990904", "evidence": [ { "database": "UniProtKB", "id": "F1NZK8", "url": "https://www.uniprot.org/uniprotkb/F1NZK8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 469, "end_pos": 471, "annotation": "n_glycosylation_sequon" }, { "start_pos": 935, "end_pos": 937, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "19669", "name": "", "equation": "GTP + H2O = GDP + phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YVX9-1", "F1NSA8-1", "R4GJA4-1", "A0A1L1RKZ0-1", "E1BUS1-1", "Q5ZHW4-1", "Q90694-1", "P08070-1", "P09642-1", "P09643-1", "P09644-1", "P09645-1", "Q5F352-1", "Q5ZMS3-1", "Q90705-1", "Q90835-1", "Q90965-1", "Q98932-1", "A0A3Q2UHM4-1", "Q5ZHX1-1", "A0A1D5PT95-1", "E1BQI2-1", "F1NPF0-1", "A0A8V0XVU5-1", "A0A8V0XBX5-1", "A0A8V0Z564-1", "A0A8V0Y9R6-1", "A0A1D5PM27-1", "A0A8V0Z8U4-1", "A0A8V0ZJW2-1", "A0A8V1ABB1-1", "A0A8V0YDX6-1", "E1BWN3-1", "Q5F499-1", "Q5ZKU5-1", "P02552-1", "P08642-1", "P26990-1", "P42558-1", "Q5F470-1", "Q5ZIT5-1", "Q5ZJN2-1", "P50146-1", "A0A8V0ZNW3-1", "A0A8V0YIM0-1", "A0A8V0ZRZ2-1", "A0A8V1A9Z8-1", "Q1KME6-1", "Q5ZLG1-1", "P84172-1", "A0A8V1ACG4-1", "A0A8V0YTL7-1", "A0A3Q2UG55-1", "A0A8V1AIF5-1", "Q5ZHV1-1", "A0A8V0Z5P2-1", "A0A8V0Y4A4-1", "A0A8V0YA62-1", "A0A8V0YVM3-1", "A0A1D5P1F5-1", "A0A8V1ADZ7-1", "F1NWF1-1", "A0A8V1AP30-1", "A0A8V0XDD5-1", "A0A8V0XMC5-1", "A0A8V0YWW1-1", "A0A8V0ZR14-1", "A0A8V0Y2H3-1", "Q5ZJD3-1", "Q5ZM73-1", "Q5ZM83-1", "A0A8V0YTY9-1", "A0A8V0ZXW3-1", "A0A8V1AHB3-1", "A0A8V0YDI7-1", "A0A1D5NV13-1", "A0A8V0XGK7-1", "A0A8V0YHK2-1", "A0A8V0XC33-1", "A0A8V0XKC3-1", "F1P278-1", "A0A8V0ZG00-1", "A0A8V1AGP3-1", "A0A8V1AN75-1", "A0A8V0Z416-1", "A0A8V1A0V4-1", "A0A8V1A8Q7-1", "A0A8V1ABD3-1", "A0A8V1API8-1", "A0A8V0YIU8-1", "A0A8V0X962-1", "A0A8V1AKH3-1", "P79784-1", "A0A1D5P533-1", "A0A8V1A8I5-1", "A0A8V1AE09-1", "Q9PSX7-1", "Q5ZKR4-1", "A0A8V0YGN8-1", "A0A8V0XNL0-1", "A0A8V0Y3H2-1" ], "evidence": [ { "id": "19669", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/19669" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A1D5NV13", "gene_name": "RIT2", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5NV13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NV13" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A1D5NV13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NV13" } ] } ] }, { "uniprot_ac": "A0A1D5P1F5", "gene_name": "RAB40C", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5P1F5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P1F5" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A1D5P1F5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P1F5" } ] } ] }, { "uniprot_ac": "A0A1D5P533", "gene_name": "RASEF", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5P533", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P533" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A1D5P533", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P533" } ] } ] }, { "uniprot_ac": "A0A1D5PM27", "gene_name": "OPA1", "activity": [ { "ec_number": "3.6.5.5", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5PM27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PM27" } ] }, { "ec_number": "3.6.5.5", "activity": "", "evidence": [ { "id": "A0A1D5PM27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PM27" } ] } ] }, { "uniprot_ac": "A0A1D5PT95", "gene_name": "KRAS", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5PT95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PT95" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A1D5PT95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PT95" } ] } ] }, { "uniprot_ac": "A0A1L1RKZ0", "gene_name": "RASL11AL", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A1L1RKZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RKZ0" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A1L1RKZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RKZ0" } ] } ] }, { "uniprot_ac": "A0A3Q2UG55", "gene_name": "RAB9B", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q2UG55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UG55" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A3Q2UG55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UG55" } ] } ] }, { "uniprot_ac": "A0A3Q2UHM4", "gene_name": "DNM1L", "activity": [ { "ec_number": "3.6.5.5", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q2UHM4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UHM4" } ] }, { "ec_number": "3.6.5.5", "activity": "", "evidence": [ { "id": "A0A3Q2UHM4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UHM4" } ] } ] }, { "uniprot_ac": "A0A8V0X962", "gene_name": "RAB31", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0X962", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X962" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V0X962", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X962" } ] } ] }, { "uniprot_ac": "A0A8V0XBX5", "gene_name": "RAP2B", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XBX5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XBX5" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V0XBX5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XBX5" } ] } ] }, { "uniprot_ac": "A0A8V0XC33", "gene_name": "RAB23", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XC33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XC33" } ] }, { 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], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052554.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_001233490", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001233490" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NMM3", "url": "https://www.uniprot.org/uniprotkb/F1NMM3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ZBTB8OS", "url": "https://www.uniprot.org/uniprotkb/F1NMM3", "locus": { "chromosome": "23", "start_pos": 5586319, "end_pos": 5590963, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010017636", "url": "https://www.ensembl.org/id/ENSGALG00010017636" } ] } } ], "crossref": [ { "id": "F1NMM3", "url": "https://alphafold.ebi.ac.uk/entry/F1NMM3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000003517", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000003517", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "419663", "url": "https://www.ncbi.nlm.nih.gov/gene/419663", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002804", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002804", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023572", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023572", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036820", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036820", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:419663", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419663", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "AITYHKM", "url": "https://omabrowser.org/oma/group/AITYHKM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z209", "url": "https://www.orthodb.org/?gene=A0A8V0Z209", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z3P6", "url": "https://www.orthodb.org/?gene=A0A8V0Z3P6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NMM3", "url": "https://www.orthodb.org/?gene=F1NMM3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12682", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12682", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12682:SF11", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12682:SF11", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01951", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01951", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_001233490", "url": 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"MAGGERDYSLTEEQKAVKAKYPPLTRKYEYLDHTADVQLHAWGDTLEEAFEQCAMAMFGYMTDTETVEPLDTVEVEAEGHDMLSLLFHFLDEWLYKFSANEFFIPREVKVLYIDRMQFKIRSIGWGEEFSLPKHPQGTEVKAITYSAMQICEEEKPEVFVIIDI", "length": 164, "header": "tr|F1NMM3-1|F1NMM3_CHICK Isoform 1 of Zinc finger and BTB domain containing 8 opposite strand OS=Gallus gallus OX=9031 GN=ZBTB8OS PE=1 SV=2 CANONICAL=F1NMM3-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z209-1", "url": "https://www.uniprot.org/uniprotkb/F1NMM3/entry#A0A8V0Z209-1", "sequence": { "sequence": "MAGGERDYSLTEEQKAVKAKYPPLTRKYEYLDHTADVQLHAWGDTLEEAFEQCAMAMFGYMTDTETVEPLDTVEVEAEGHDMLSLLFHFLDEWLYKFSANEFFIPREVKVLYIDRMQFKIRSIGVGRRVLFTKTPPGHRGQSHNLLSHADL", "length": 151, "header": "tr|A0A8V0Z209-1|A0A8V0Z209_CHICK Computationally mapped isoform of Zinc finger and BTB domain containing 8 opposite strand OS=Gallus gallus OX=9031 GN=ZBTB8OS PE=1 SV=1 CANONICAL=F1NMM3-1" }, "locus": { "chromosome": "23", "start_pos": 5590013, "end_pos": 5587378, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042621.1", "url": "https://www.ensembl.org/id/ENSGALT00010042621.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025111.1", "url": "https://www.ensembl.org/id/ENSGALP00010025111.1" } ] } }, { "isoform_ac": "A0A8V0Z3P6-1", "url": "https://www.uniprot.org/uniprotkb/F1NMM3/entry#A0A8V0Z3P6-1", "sequence": { "sequence": "MAGGERDYSLTEEQKAVKAKYPPLTRKYECEWLLHAWGDTLEEAFEQCAMAMFGYMTDTETVEPLDTVEVEAEGHDMLSLLFHFLDEWLYKFSANEFFIPREVKVLYIDRMQFKIRSIGWGEEFSLPKHPQGTEVKAITYSAMQICEEEKPEVFVIIDI", "length": 159, "header": "tr|A0A8V0Z3P6-1|A0A8V0Z3P6_CHICK Computationally mapped isoform of Zinc finger and BTB domain containing 8 opposite strand OS=Gallus gallus OX=9031 GN=ZBTB8OS PE=1 SV=1 CANONICAL=F1NMM3-1" }, "locus": { "chromosome": "23", "start_pos": 5590013, "end_pos": 5587338, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042617.1", "url": "https://www.ensembl.org/id/ENSGALT00010042617.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025107.1", "url": "https://www.ensembl.org/id/ENSGALP00010025107.1" } ] } }, { "isoform_ac": "F1NMM3-1", "url": "https://www.uniprot.org/uniprotkb/F1NMM3/entry#F1NMM3-1", "sequence": { "sequence": "MAGGERDYSLTEEQKAVKAKYPPLTRKYEYLDHTADVQLHAWGDTLEEAFEQCAMAMFGYMTDTETVEPLDTVEVEAEGHDMLSLLFHFLDEWLYKFSANEFFIPREVKVLYIDRMQFKIRSIGWGEEFSLPKHPQGTEVKAITYSAMQICEEEKPEVFVIIDI", "length": 164, "header": "tr|F1NMM3-1|F1NMM3_CHICK Isoform 1 of Zinc finger and BTB domain containing 8 opposite strand OS=Gallus gallus OX=9031 GN=ZBTB8OS PE=1 SV=2 CANONICAL=F1NMM3-1" }, "locus": { "chromosome": "23", "start_pos": 5590013, "end_pos": 5587338, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042618.1", "url": "https://www.ensembl.org/id/ENSGALT00010042618.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025108.1", "url": "https://www.ensembl.org/id/ENSGALP00010025108.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:419663", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419663", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "G3H938-1", "protein_name": "tRNA-splicing ligase-activating factor archease", "gene_name": "Zbtb8os", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAQEEEDVRDYNLTEEQKAIKDKYPPVNRKYEYLDHTADVQLHAWGDTLEEAFEQCAMAMFGYMTDTGTVEPLQTVEVETQGDDLQSLLFHFLDEWLYKFSADEYFIPREVKVLNIDQKNFKLRSIGWGEEFSLSKHPQGTEVKAITYSAMQVYNEEKPEVFVIIDI", "length": 167 }, "evidence": [ { "id": "F1NMM3", "url": "https://omabrowser.org/oma/group/F1NMM3/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "I3L7E1-1", "protein_name": "tRNA-splicing ligase-activating factor archease", "gene_name": "ZBTB8OS", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MALEGEDFRDYNLTEEQKAIKAKYPPVNRKYEYLDHTADVQLHAWGDTLEEAFEQCAMAMFGYMTDTGTVEPLQTMEVETQGDDLQSLLFHFLDEWLYKFSADEFFIPREVKVLNIDQRNFKLRSIGWGEEFSLSKHPQGTEVKAITYSAMQVYNEEKPEVFVIIDI", "length": 167 }, "evidence": [ { "id": "F1NMM3", "url": "https://omabrowser.org/oma/group/F1NMM3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "M0R5Y9-1", "protein_name": "tRNA-splicing ligase-activating factor archease", "gene_name": "Zbtb8os", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAQEEEDVRDYNLTEEQKAIKNKYPPVNRKYEYLDHTADVQLHAWGDTLEEAFEQCAMAMFGYMTDTGTVEPLQTVEVETQGDDLQSLLFHFLDEWLYRFSADEYFIPREVKVLNIDQKNFKLRSIGWGEEFSLSKHPQGTEVKAITYSAMQVYNEEKPEVFVIIDI", "length": 167 }, "evidence": [ { "id": "F1NMM3", "url": "https://omabrowser.org/oma/group/F1NMM3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q2YDE7-1", "protein_name": "tRNA-splicing ligase-activating factor archease", "gene_name": "ZBTB8OS", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MALEGEDVRDYNLTEEQKAIKAKYPPVSRKYEYLDHTADVQLHAWGDTLEEAFEQCAMAMFGYMTDTGTVEPLQTIEVETQGDDLQSLLFHFLDEWLYKFSADEFFIPREVKVLNIDQRNFKIRSIGWGEEFSLSKHPQGTEVKAITYSAMQVYNEEKPEVFVIIDI", "length": 167 }, "evidence": [ { "id": "F1NMM3", "url": "https://omabrowser.org/oma/group/F1NMM3/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q505B7-1", "protein_name": "tRNA-splicing ligase-activating factor archease", "gene_name": "Zbtb8os", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAQEEEDVRDYNLTEEQKATKDKYPPVNRKYEYLDHTADVQLHAWGDTLEEAFEQCAMAMFGYMTDTGTVEPLRTVEVETQGDDLQSLLFHFLDEWLYKFSADEYFIPREVKVLNIDQKNFKLRSIGWGEEFSLSKHPQGTEVKAITYSAMQVYNEEKPEVFFVIIDI", "length": 168 }, "evidence": [ { "id": "F1NMM3", "url": "https://omabrowser.org/oma/group/F1NMM3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q54BU9-1", "protein_name": "Protein archease-like", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MESYGLGQLKNFEYLDHTADIMFHTWGKDLKEALEQMVLIMNNYMVELDSVELDDSATEQTISVNGHDMDSLLFALLDEFLFVFSTEFIIFKQVQIISFDRENFSIKAIGKGVELDKSKHTTGTEIKAITYSCMKIEENPDKSDIHVIVDI", "length": 151 }, "evidence": [ { "id": "F1NMM3", "url": "https://omabrowser.org/oma/group/F1NMM3/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q566V0-1", "protein_name": "tRNA-splicing ligase-activating factor archease", "gene_name": "zbtb8os", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MNDRELDLTEEQKALKAKYPPITKKYEYLDHTADVQIHSWGNSLEEAFEQCAMGMFGYMTDTETVEPIDTVEVESEGDDMESLLYHFLDDWLFKFSADIFFIPREVKVLHIDRMRYKIRSIGWGEEFSINKHPQGTEVKAITYSAMQIHETEQPEIFVIIDI", "length": 162 }, "evidence": [ { "id": "F1NMM3", "url": "https://omabrowser.org/oma/group/F1NMM3/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q9VD92-1", "protein_name": "Protein archease-like", "gene_name": "Archease", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MEVEFSRENFLLPEMKYEYLDHTADVQIHGWGSSLKEAFEQCGVAMFGYMTELDYVSVEQCFEIEAHGDDLESLLFHFLDELLFLFSAEPYLVCKKLEITKFDVENFEISCHCYGEPFELGKHPQGTEVKAITYSAMQIIQDVEASNYEVFVIIDI", "length": 156 }, "evidence": [ { "id": "F1NMM3", "url": "https://omabrowser.org/oma/group/F1NMM3/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "tRNA processing", "id": "GO:0008033", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008033", "evidence": [ { "database": "UniProtKB", "id": "F1NMM3", "url": "https://www.uniprot.org/uniprotkb/F1NMM3" } ], "pmid": "" }, { "name": "mRNA splicing, via endonucleolytic cleavage and ligation", "id": "GO:0070054", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070054", "evidence": [ { "database": "UniProtKB", "id": "F1NMM3", "url": "https://www.uniprot.org/uniprotkb/F1NMM3" } ], "pmid": "" }, { "name": "IRE1-mediated unfolded protein response", "id": "GO:0036498", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036498", "evidence": [ { "database": "UniProtKB", "id": "F1NMM3", "url": "https://www.uniprot.org/uniprotkb/F1NMM3" } ], "pmid": "" }, { "name": "tRNA splicing, via endonucleolytic cleavage and ligation", "id": "GO:0006388", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006388", "evidence": [ { "database": "UniProtKB", "id": "F1NMM3", "url": "https://www.uniprot.org/uniprotkb/F1NMM3" } ], "pmid": "" }, { "name": "tRNA exon ligation", "id": "GO:0000968", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000968", "evidence": [ { "database": "UniProtKB", "id": "F1NMM3", "url": "https://www.uniprot.org/uniprotkb/F1NMM3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "F1NMM3", "url": "https://www.uniprot.org/uniprotkb/F1NMM3" } ], "pmid": "" }, { "name": "protein guanylyltransferase activity", "id": "GO:0044600", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044600", "evidence": [ { "database": "UniProtKB", "id": "F1NMM3", "url": "https://www.uniprot.org/uniprotkb/F1NMM3" } ], "pmid": "" }, { "name": "RNA ligase (GTP) activity", "id": "GO:0170057", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0170057", "evidence": [ { "database": "UniProtKB", "id": "F1NMM3", "url": "https://www.uniprot.org/uniprotkb/F1NMM3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1NMM3", "url": "https://www.uniprot.org/uniprotkb/F1NMM3" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1NMM3", "url": "https://www.uniprot.org/uniprotkb/F1NMM3" } ], "pmid": "" }, { "name": "tRNA-splicing ligase complex", "id": "GO:0072669", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072669", "evidence": [ { "database": "UniProtKB", "id": "F1NMM3", "url": "https://www.uniprot.org/uniprotkb/F1NMM3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1NMM3-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 164, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1NMM3-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1NMM3" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1NMM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NMM3" }, { "id": "PF01951", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01951" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Archease", "eco_id": "ECO_0000259", "start_pos": 28, "end_pos": 164, "start_aa": "Tyr", "end_aa": "Ile", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1NV54-1", "uniprot_ac": "F1NV54", "uniprot_id": "F1NV54_CHICK", "mass": { "chemical_mass": 47629.0, "monoisotopic_mass": 47629.0 }, "refseq": { "ac": "NP_001034373", "name": "forkhead box protein N2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001034373" }, "gene_names": [ { "name": "FOXN2", "type": "recommended", "evidence": [ { "id": "F1NV54", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NV54" } ] }, { "name": "FOXN2", "type": "synonym", "evidence": [ { "id": "NP_001034373", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001034373" } ] }, { "name": "HTLF", "type": "synonym", "evidence": [ { "id": "NP_001034373", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001034373" } ] } ], "protein_names": [ { "name": "Forkhead box protein G1", "type": "recommended", "evidence": [ { "id": "F1NV54", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NV54/entry#names_and_taxonomy" } ] }, { "name": "forkhead box protein N2", "type": "synonym", "evidence": [ { "id": "NP_001034373", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001034373" } ] }, { "name": "human T-cell leukemia virus enhancer factor", "type": "synonym", "evidence": [ { "id": "NP_001034373", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001034373" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ721059.1, SRR13267654.25047.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000061.1. On Mar 5, 2015 this sequence version replaced NP_001034373.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001034373", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001034373" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NV54", "url": "https://www.uniprot.org/uniprotkb/F1NV54" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "FOXN2", "url": "https://www.uniprot.org/uniprotkb/F1NV54", "locus": { "chromosome": "3", "start_pos": 9125562, "end_pos": 9099262, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010017768", "url": "https://www.ensembl.org/id/ENSGALG00010017768" } ] } } ], "crossref": [ { "id": "F1NV54", "url": "https://alphafold.ebi.ac.uk/entry/F1NV54", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000008942", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000008942", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd20058", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd20058", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "421288", "url": "https://www.ncbi.nlm.nih.gov/gene/421288", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001766", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001766", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018122", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018122", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR030456", "url": "https://www.ebi.ac.uk/interpro/entry/IPR030456", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036388", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036388", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036390", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036390", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047119", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047119", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047403", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047403", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:421288", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:421288", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "GYVSQPC", "url": "https://omabrowser.org/oma/group/GYVSQPC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z2Y1", "url": "https://www.orthodb.org/?gene=A0A8V0Z2Y1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NV54", "url": "https://www.orthodb.org/?gene=F1NV54", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13962", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13962", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13962:SF19", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13962:SF19", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00250", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00250", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001034373", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001034373", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Z2Y1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2Y1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z2Y1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2Y1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NV54", "url": "https://www.uniprot.org/uniprotkb/F1NV54", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NV54-1", "url": "https://www.uniprot.org/uniprotkb/F1NV54-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGPVTGMTPDKKAKTPGAEKAAGLRQSHRMGSLPDAGDAGRPKATVVDSDSADDELTNLNWLHESTNLLTNFSLGSEGLPIVSPLYDIEGDSVPSFSPSCYQNPEKKSSTSKPPYSFSLLIYMAIEHSPNKSLPVKEIYSWILERFPYFATAPTGWKNSVRHNLSLNKCFRKVERSHGKVNGKGSLWCVDPEYKPNLVQALKKQPFPSALAFYTPPASPPSRSSSPHYLSSVLKQNNGRSLKESDIDAATAMMLLNTSIEQGMLDCEKPQSLKTPKKRSYGSAFNHPSSSINLQENDSAATNIDPKEDHNYSASSMGSQRCASRSSVSSLSSVDEVYEFISKNSHAGSDGSEGFHSEVDTDVDYEDDPLGDSGYASQPCVDTSEKSQPSNKALKELCQEIDEELKEAAGSLLHLAGIQTCLGSLISTAKTHSHKQRKK", "length": 438, "header": "tr|F1NV54-1|F1NV54_CHICK Isoform 1 of Forkhead box protein G1 OS=Gallus gallus OX=9031 GN=FOXN2 PE=4 SV=2 CANONICAL=F1NV54-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z2Y1-1", "url": "https://www.uniprot.org/uniprotkb/F1NV54/entry#A0A8V0Z2Y1-1", "sequence": { "sequence": "MGPVTGMTPDKKAKTPGAEKAAGLRQSHRMGSLPDAGDAGRPKATVVDSDSADDELTNLNWLHESTNLLTNFSLGSEGLPIVSPLYDIEGDSVPSFSPSCYQNPEKKSSTSKPPYSFSLLIYMAIEHSPNKSLPVKEIYSWILERFPYFATAPTGWKNSVRHNLSLNKCFRKVERSHGKVNGKGSLWCVDPEYKPNLVQALKKQPFPSALAFYTPPASPPRSSSPHYLSSVLKQNNGRSLKESDIDAATAMMLLNTSIEQGMLDCEKPQSLKTPKKRSYGSAFNHPSSSINLQENDSAATNIDPKEDHNYSASSMGSQRCASRSSVSSLSSVDEVYEFISKNSHAGSDGSEGFHSEVDTDVDYEDDPLGDSGYASQPCVDTSEKSQPSNKALKELCQEIDEELKEAAGSLLHLAGIQTCLGSLISTAKTHSHKQRKK", "length": 437, "header": "tr|A0A8V0Z2Y1-1|A0A8V0Z2Y1_CHICK Computationally mapped isoform of Forkhead box protein G1 OS=Gallus gallus OX=9031 GN=FOXN2 PE=4 SV=1 CANONICAL=F1NV54-1" }, "locus": { "chromosome": "3", "start_pos": 9125121, "end_pos": 9111064, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042944.1", "url": "https://www.ensembl.org/id/ENSGALT00010042944.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025434.1", "url": "https://www.ensembl.org/id/ENSGALP00010025434.1" } ] } }, { "isoform_ac": "F1NV54-1", "url": "https://www.uniprot.org/uniprotkb/F1NV54/entry#F1NV54-1", "sequence": { "sequence": "MGPVTGMTPDKKAKTPGAEKAAGLRQSHRMGSLPDAGDAGRPKATVVDSDSADDELTNLNWLHESTNLLTNFSLGSEGLPIVSPLYDIEGDSVPSFSPSCYQNPEKKSSTSKPPYSFSLLIYMAIEHSPNKSLPVKEIYSWILERFPYFATAPTGWKNSVRHNLSLNKCFRKVERSHGKVNGKGSLWCVDPEYKPNLVQALKKQPFPSALAFYTPPASPPSRSSSPHYLSSVLKQNNGRSLKESDIDAATAMMLLNTSIEQGMLDCEKPQSLKTPKKRSYGSAFNHPSSSINLQENDSAATNIDPKEDHNYSASSMGSQRCASRSSVSSLSSVDEVYEFISKNSHAGSDGSEGFHSEVDTDVDYEDDPLGDSGYASQPCVDTSEKSQPSNKALKELCQEIDEELKEAAGSLLHLAGIQTCLGSLISTAKTHSHKQRKK", "length": 438, "header": "tr|F1NV54-1|F1NV54_CHICK Isoform 1 of Forkhead box protein G1 OS=Gallus gallus OX=9031 GN=FOXN2 PE=4 SV=2 CANONICAL=F1NV54-1" }, "locus": { "chromosome": "3", "start_pos": 9125121, "end_pos": 9111064, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042938.1", "url": "https://www.ensembl.org/id/ENSGALT00010042938.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025428.1", "url": "https://www.ensembl.org/id/ENSGALP00010025428.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:421288", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:421288", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3Q1N300-1", "protein_name": "Forkhead box N2", "gene_name": "FOXN2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGPVIGMTPEKRAETPGAEKVAGLSQIYKMGSLPEAVDAARPKATLVDNESADDELTNLNWLHESTNLLTNFSFGSEGLPIVSPLYDIEGDDVPSFGPSCYQSQEKKSATSKPPYSFSLLIYMAIEHSPNKCLPVKEIYSWILNRFPYFATAPTGWKNSVRHNLSLNKCFQKVERSHGKVNGKGSLWCVDPEYKPNLMQALKKQPFSSKSTFYSPPASPQSGSLSPHYLSSVLKQNQVRTLKESDIDAATAMMLLNTSIEQGILECEKPLPLKTAMQKKRSYSNAFNHSSAMRLHESDSLATSIDPKEDHNYSASSMAAQRCASRSSVSSLSSVDEVYEFIPKSSHVGSDGSEGFRSEEDTDVDYEDDPLGDSGYASQACADTTEKGQPDKKMRKQACQEIDEELKEAAGSLLHLAGIRTCLGSLISTAKTQNQKQRKK", "length": 439 }, "evidence": [ { "id": "F1NV54", "url": "https://omabrowser.org/oma/group/F1NV54/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A8C2M2U2-1", "protein_name": "Forkhead box protein N2", "gene_name": "Foxn2", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MGPVIGMTPDKKAETPGAEKVAGLSQIYKMGSLPEVGDAARPKATLVGSDSADDELTNLNWLHESSNLLTNFRLGTEGLPMVSPLYDIEGDDMPAFGPSYCQNPEQQSATSKPPYSFSLLIYMAIEHSPNKCLPVKDIYSWILDRFPYFATAPTGWKNSVRHNLSLNKCFQKVERSHGKVNGKGSLWCVDPEYKPNLMQALKKQPFSSPQSGSLSPHYLNSVLKQSQVQTLKESDIDAATAMILLNTSIEQEILECDKPLPLKPSLQKKRGYGIAFSAPGAVQLQESHSPAASIDPKADHNYSASSMAAQRCASRASVSSLSSVDEVYEFIPKSSHVGSDGSEGFHSEEDTDADEEDDPLGDSGYATQAHEVNAPKGQPGKKMRKQSCQEIDEELKEAAGSLLHLAGIRTCLGSLISTAKAQSHKHRKK", "length": 429 }, "evidence": [ { "id": "F1NV54", "url": "https://omabrowser.org/oma/group/F1NV54/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "E9Q7L6-1", "protein_name": "Forkhead box N2", "gene_name": "Foxn2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGPVIGMTPDKRAETPGAEKVAGLSQIYKMGSLPEAGDAARPKATLVGSESADDELTNLNWLHESSNLLTNLRLGSEGLPMVSPLYDIEGDEMPSFGPSCYQNPEKKSATSKPPYSFSLLIYMAIEHSPNKCLPVKEIYSWILDRFPYFATAPTGWKNSVRHNLSLNKCFQKVERSHGKVNGKGSLWCVDPEYKPNLMQALKKQPFSSPQSAALSPHCLSSALKQSQVQTLQESDIDAATAMILLNTSIEQEILECEKPLPLKTSLQKKRSYGSAFSAPGAVRLQESPSPTAGIDPKADHNYSANSVAAQRCASRASMSSLSSVDEVYEFIPKSSHGGSDGSEGFHSDEETDAEDEEDPLGDSGYAPQARGHSTLKGQPGKKIPKQSCQEIDEELKEAAGSLLHLAGIRTCLGSLISTAKAQSQKHREK", "length": 429 }, "evidence": [ { "id": "F1NV54", "url": "https://omabrowser.org/oma/group/F1NV54/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F1LZM0-1", "protein_name": "Forkhead box N2", "gene_name": "Foxn2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGPVIGMTPDKRAETPGAEKVAGLSQIYKMGSLPEAGEASRPKATLVGSDSTDDELTNLNWLHESSDLLTNLRLGGEGLPMVSPLYDIEGDDMPSFGPLCCQNPEKKSATSKPPYSFSLLIYMAIEHSPNKCLPVKEIYSWILDRFPYFATAPTGWKNSVRHNLSLNKCFQKVERSHGKVNGKGSLWCVDPEYKPNLVQALKKQPFSSPQSASLSPHYLSSVLKQSQVQTLKESDIDAATAMILLNTSIEQEMLECEKPLPLKTSLQKKRSYGSAFSAPSAVQLQESHSPASSIDPKADHNYSASGVAAQRCASRASMSSLSSVDEVYEFIPKSSHGGSDGSEGFHSDEETDAEDEDPLADSGYAPQALEDSTRKGQPGQKIPKQSCQEIDEELKEAAGSLLHLAGIRTCLGSLISTAKAQSQKHRKK", "length": 428 }, "evidence": [ { "id": "F1NV54", "url": "https://omabrowser.org/oma/group/F1NV54/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P32314-1", "protein_name": "Forkhead box protein N2", "gene_name": "FOXN2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGPVIGMTPDKRAETPGAEKIAGLSQIYKMGSLPEAVDAARPKATLVDSESADDELTNLNWLHESTNLLTNFSLGSEGLPIVSPLYDIEGDDVPSFGPACYQNPEKKSATSKPPYSFSLLIYMAIEHSPNKCLPVKEIYSWILDHFPYFATAPTGWKNSVRHNLSLNKCFQKVERSHGKVNGKGSLWCVDPEYKPNLIQALKKQPFSSASSQNGSLSPHYLSSVIKQNQVRNLKESDIDAAAAMMLLNTSIEQGILECEKPLPLKTALQKKRSYGNAFHHPSAVRLQESDSLATSIDPKEDHNYSASSMAAQRCASRSSVSSLSSVDEVYEFIPKNSHVGSDGSEGFHSEEDTDVDYEDDPLGDSGYASQPCAKISEKGQSGKKMRKQTCQEIDEELKEAAGSLLHLAGIRTCLGSLISTAKTQNQKQRKK", "length": 431 }, "evidence": [ { "id": "F1NV54", "url": "https://omabrowser.org/oma/group/F1NV54/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "F1NV54", "url": "https://www.uniprot.org/uniprotkb/F1NV54" } ], "pmid": "" }, { "name": "sequence-specific DNA binding", "id": "GO:0043565", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043565", "evidence": [ { "database": "UniProtKB", "id": "F1NV54", "url": "https://www.uniprot.org/uniprotkb/F1NV54" } ], "pmid": "" }, { "name": "cis-regulatory region sequence-specific DNA binding", "id": "GO:0000987", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000987", "evidence": [ { "database": "UniProtKB", "id": "F1NV54", "url": "https://www.uniprot.org/uniprotkb/F1NV54" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1NV54", "url": "https://www.uniprot.org/uniprotkb/F1NV54" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "F1NV54", "url": "https://www.uniprot.org/uniprotkb/F1NV54" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "F1NV54", "url": "https://www.uniprot.org/uniprotkb/F1NV54" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "F1NV54", "url": "https://www.uniprot.org/uniprotkb/F1NV54" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 130, "end_pos": 132, "annotation": "n_glycosylation_sequon" }, { "start_pos": 163, "end_pos": 165, "annotation": "n_glycosylation_sequon" }, { "start_pos": 256, "end_pos": 258, "annotation": "n_glycosylation_sequon" }, { "start_pos": 296, "end_pos": 298, "annotation": "n_glycosylation_sequon" }, { "start_pos": 310, "end_pos": 312, "annotation": "n_glycosylation_sequon" }, { "start_pos": 71, "end_pos": 73, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1NV54-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 438, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1NV54-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1NV54" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1NV54", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NV54" }, { "id": "PS50039", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50039" }, { "id": "PRU00089", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00089" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Fork-head", "eco_id": "ECO_0000259", "start_pos": 112, "end_pos": 199, "start_aa": "Lys", "end_aa": "Gln", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 130, "end_pos": 132 }, { "start_pos": 163, "end_pos": 165 }, { "start_pos": 256, "end_pos": 258 }, { "start_pos": 296, "end_pos": 298 }, { "start_pos": 310, "end_pos": 312 }, { "start_pos": 71, "end_pos": 73 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1NZA5-1", "uniprot_ac": "F1NZA5", "uniprot_id": "F1NZA5_CHICK", "mass": { "chemical_mass": 63978.0, "monoisotopic_mass": 63978.0 }, "refseq": { "ac": "XP_004943910", "name": "DET1 homolog isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004943910" }, "gene_names": [ { "name": "DET1", "type": "recommended", "evidence": [ { "id": "F1NZA5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NZA5" } ] }, { "name": "DET1", "type": "synonym", "evidence": [ { "id": "XP_004943910", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004943910" } ] } ], "protein_names": [ { "name": "DET1 homolog isoform X1", "type": "synonym", "evidence": [ { "id": "XP_004943910", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004943910" } ] }, { "name": "DET1 partner of COP1 E3 ubiquitin ligase", "type": "synonym", "evidence": [ { "id": "F1NZA5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NZA5/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052541.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004943910", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004943910" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NZA5", "url": "https://www.uniprot.org/uniprotkb/F1NZA5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "DET1", "url": "https://www.uniprot.org/uniprotkb/F1NZA5", "locus": { "chromosome": "10", "start_pos": 13185467, "end_pos": 13162827, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010020199", "url": "https://www.ensembl.org/id/ENSGALG00010020199" } ] } } ], "crossref": [ { "id": "F1NZA5", "url": "https://alphafold.ebi.ac.uk/entry/F1NZA5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000006750", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000006750", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "415497", "url": "https://www.ncbi.nlm.nih.gov/gene/415497", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR019138", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019138", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:415497", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:415497", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "ITPCLTI", "url": "https://omabrowser.org/oma/group/ITPCLTI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z6H3", "url": "https://www.orthodb.org/?gene=A0A8V0Z6H3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NZA5", "url": "https://www.orthodb.org/?gene=F1NZA5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13374", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13374", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13374:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13374:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF09737", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09737", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-983168", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983168", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_004943910", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004943910", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Z6H3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6H3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z6H3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6H3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NZA5", "url": "https://www.uniprot.org/uniprotkb/F1NZA5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NZA5-1", "url": "https://www.uniprot.org/uniprotkb/F1NZA5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDHDAPTIKPRRIQNQNVIHRLERRRISSGKAGTHWHQVRVFHQNVFPNFTVVNVEKPPCFLRKFSPDGRYFIAFSSDQTSLEIYEYQGCQAAEDLLQGYEGEILANGNDQRSVNIRGRLFERFFVLLHITNVASNGEHLNRECSLFTDDCRYVIVGSAAYLPEEPHPPFFEVYRNSESVTPNPRSPLEDYSLHIIDLHTGRLCDTRTFKCDKVILSHNQGLYLYKNILAILSVQQQTIHVFQVTPEGTFIDVRTIGRFCYEDDLLTLSAVYPEVQRDTQTGMANPYKEPFINSLKHRLLVYLWRRAEQDGSAIAKRRFFQYFDQLRQLRMWKMQLLDENHLFIKYTSEDVVTLRVTDPSQPSFFVVYNMVSTEVIAVFENTSDELLELFENFCDLFRNATLHSEAVQFPCSASSNNFARQIQRRFKDTIVNAKYGGHTEAVRRLLGQLPISAQSYSGSPYLDLSLFSYDDKWVSVMERPKTCGDHPIRFYARDSGLLKFEIQAGLLGRPINHTVRRLVAFTFHPFEPFAISVQRTNAEYVVNFHMRHSCT", "length": 551, "header": "tr|F1NZA5-1|F1NZA5_CHICK Isoform 1 of DET1 partner of COP1 E3 ubiquitin ligase OS=Gallus gallus OX=9031 GN=DET1 PE=4 SV=2 CANONICAL=F1NZA5-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z6H3-1", "url": "https://www.uniprot.org/uniprotkb/F1NZA5/entry#A0A8V0Z6H3-1", "sequence": { "sequence": "MDHDAPTIKPRRIQNQNVIHRLERRRISSGKAGTHWHQVRVFHQNVFPNFTVVNVEKPPCFLRKFSPDGRYFIAFSSDQTSLEIYEYQGCQAAEDLLQGYEGEILANGNDQRSVNIRGRLFERFFVLLHITNVASNGEHLNRECSLFTDDCRYVIVGSAAYLPEEPHPPFFEVYRNSESVTPNPRSPLEDYSLHIIDLHTGRLCDTRTFKCDKVILSHNQGLYLYKNILAILSVQQQTIHVFQVTPEGTFIDVRTIGRFCYEDDLLTLSAVYPEVQRDTQTGMANPYKEPFINSLKHRLLVYLWRRAEQDGSAIAKRRFFQYFDQLRQLRMWKMQLLDENHLFIKYTSEDVVTLRVTDPSQPSFFVVYNMVSTEVIAVFENTSDELLELFENFCDLFRNATLHSEAVQFPCSASSNNFARQIQRRFKDTIVNAKYGGHTEAVRRLLGQLPISAQSYSGSPYLDLSLFSYDDKWVSVMERPKTCGDHPIRSSSKSSLWYTRQNQRDCKQQNWHNPSSFEGLAFSICQQR", "length": 528, "header": "tr|A0A8V0Z6H3-1|A0A8V0Z6H3_CHICK Computationally mapped isoform of DET1 partner of COP1 E3 ubiquitin ligase OS=Gallus gallus OX=9031 GN=DET1 PE=4 SV=1 CANONICAL=F1NZA5-1" }, "locus": { "chromosome": "10", "start_pos": 13184051, "end_pos": 13163575, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048787.1", "url": "https://www.ensembl.org/id/ENSGALT00010048787.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028842.1", "url": "https://www.ensembl.org/id/ENSGALP00010028842.1" } ] } }, { "isoform_ac": "F1NZA5-1", "url": "https://www.uniprot.org/uniprotkb/F1NZA5/entry#F1NZA5-1", "sequence": { "sequence": "MDHDAPTIKPRRIQNQNVIHRLERRRISSGKAGTHWHQVRVFHQNVFPNFTVVNVEKPPCFLRKFSPDGRYFIAFSSDQTSLEIYEYQGCQAAEDLLQGYEGEILANGNDQRSVNIRGRLFERFFVLLHITNVASNGEHLNRECSLFTDDCRYVIVGSAAYLPEEPHPPFFEVYRNSESVTPNPRSPLEDYSLHIIDLHTGRLCDTRTFKCDKVILSHNQGLYLYKNILAILSVQQQTIHVFQVTPEGTFIDVRTIGRFCYEDDLLTLSAVYPEVQRDTQTGMANPYKEPFINSLKHRLLVYLWRRAEQDGSAIAKRRFFQYFDQLRQLRMWKMQLLDENHLFIKYTSEDVVTLRVTDPSQPSFFVVYNMVSTEVIAVFENTSDELLELFENFCDLFRNATLHSEAVQFPCSASSNNFARQIQRRFKDTIVNAKYGGHTEAVRRLLGQLPISAQSYSGSPYLDLSLFSYDDKWVSVMERPKTCGDHPIRFYARDSGLLKFEIQAGLLGRPINHTVRRLVAFTFHPFEPFAISVQRTNAEYVVNFHMRHSCT", "length": 551, "header": "tr|F1NZA5-1|F1NZA5_CHICK Isoform 1 of DET1 partner of COP1 E3 ubiquitin ligase OS=Gallus gallus OX=9031 GN=DET1 PE=4 SV=2 CANONICAL=F1NZA5-1" }, "locus": { "chromosome": "10", "start_pos": 13173602, "end_pos": 13163575, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048783.1", "url": "https://www.ensembl.org/id/ENSGALT00010048783.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028839.1", "url": "https://www.ensembl.org/id/ENSGALP00010028839.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:415497", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:415497", "resource": "KEGG Pathway" }, { "id": "R-GGA-983168", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983168", "resource": "Reactome", "description": "Antigen processing: Ubiquitination & Proteasome degradation" } ], "orthologs": [ { "uniprot_canonical_ac": "F1MTH1-1", "protein_name": "DET1 partner of COP1 E3 ubiquitin ligase", "gene_name": "DET1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MDHHVSTIKPRRIQNQNVIHRLERRRISSGKAGTHWHQVRVFHQNVFPNFTVVNVEKPPCFLRKFSPDGRYFIAFSSDQTSLEIYEYQGCQAAEDLLQGYEGEILANGNDQRSVNIRGRLFERFFVLLHITSVAANGEHLNRECSLFTDDCRCVIVGSAAYLPDEPHPPFYEVYRNSESVTPNPRSPLEDYSLHIVDLHTGRLCDTRTFKCDKVVLSHNQGLYLYKNILAILSVQQQTIHVFQVTPEGTFIDVRTIGRFCYEDDLLTVSAMFPEVQRDSQTGMANPFRDPFINSLKHRLLVYLWRRAEQDGSAMAKRRFFQYFDQLRQLRMWKMQLLDENHLFIKYTSEDVVTLRVTDPSQASFFVVYNMVTTEVIAVFENTSDELLELFENFCDLFRNATLHSEVQFPCSASSNNFARQIQRRFKDTIVNAKYGGHTEAVRRLLGQLPISAQSYSGSPYLDLSLFSYDDKWVSVMERPKTCGDHPIRFYARDSGLLKFEIQAGLLGRPINHTVRRLVAFTFHPFEPFAISVQRTNAEYVVNFHMRHCCT", "length": 550 }, "evidence": [ { "id": "F1NZA5", "url": "https://omabrowser.org/oma/group/F1NZA5/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F7EXD0-1", "protein_name": "DET1 partner of COP1 E3 ubiquitin ligase", "gene_name": "Det1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSQDSTDVIMDHHVSTIKPRRIQNQNVIHRLERRRISSGRAGTHWHQVRVFHQNVFPNFTVVNVEKPPCFLRKFSPDGRYFIAFSSDQTSLEIYEYQGCQAAEDLLQGYEGEILSNGNDQRSVSIRGRLFERFFVLLHITNVAANGEHLNRECSLFTDDCRCVIVGSAAYLPDEPHPPFYEVYRNSESVTPNPRSPLEDYSLHIIDLHTGRLCDTRTFKCDKVVLSHNQGLYLYKNILAILSVQQQTIHVFQVTPEGTFIDVRTIGRFCYEDDLLTVSAVFPEVQRDSQTGMANPFRDPFINSLKHRLLVYLWRRAEQDGSAMAKRRFFQYFDQLRQLRMWKMQLLDENHLFIKYTSEDVVTLRVTDPSQASFFVVYNMVTTEVIAVFENTSDELLELFENFCDLFRNATLHSEVQFPCSASSNNFARQIQRRFKDTIINAKYGGHTEAVRRLLGQLPISAQSYSGSPYLDLSLFSYDDKWVSVMERPKTCGDHPIRFYARDSGLLKFEIQAGLLGRPINHTVRRLVAFTFHPFEPFAISVQRTNAEYVVNFHMRHCCT", "length": 559 }, "evidence": [ { "id": "F1NZA5", "url": "https://omabrowser.org/oma/group/F1NZA5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P48732-1", "protein_name": "Light-mediated development protein DET1", "gene_name": "DET1", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MFTSGNVTARVFERQIRTPPPGASVNRARHFYENLVPSYTLYDVESPDHCFRKFTEDGLFLISFSRNHQELIVYRPSWLTYSTTDDSTTTLPPLPRRASKFDSFFTQLYSVNLASSNELICKDFFLYHQTRRFGLFATSTAQIHDSSSPSNDAVPGVPSIDKITFVLLRLDDGVVLDERVFLHDFVNLAHNMGVFLYDDLLAILSLRYQRIHLLQIRDSGHLVDARAIGYFCREDDELFLNSSSQAMMSQDKSKQQSLSGSKEDDTGENGLRHSLSQPSGSNSFLSGVKQRLLSFIFREIWNEESDNVMRVQSLKKKFYFHFQDYVDLIIWKVQFLDRQHLLIKFGSVDGGVTRSADHHPAFFAVYNMETTDIVAFYQNSAEDLYQLFEQFSDHFTVSSSTPFMNFVTSHSNNVYALEQLKYTKNKSNSFSQFVKKMLLSLPFSCQSQSPSPYFDQSLFRFDEKLISAADRHRQSSDNPIKFISRRQPQTLKFKIKPGPECGTADGRSKKICSFLFHPHLPLAISIQQTLFMPPSVVNIHFRR", "length": 543 }, "evidence": [ { "id": "F1NZA5", "url": "https://omabrowser.org/oma/group/F1NZA5/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9D0A0-1", "protein_name": "DET1 homolog", "gene_name": "Det1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDHHVSTIKPRRIQNQNVIHRLERRRISSGKAGTHWHQVRVFHQNVFPNFTVVNVEKPPCFLRKFSPDGRYFIAFSSDQTSLEIYEYQGCQAAEDLLQGYEGEILSNGNDQRSVSIRGRLFERFFVLLHITNVAANGEHLNRECSLFTDDCRCVIVGSAAYLPDEPHPPFYEVYRNSESVTPNPRSPLEDYSLHIIDLHTGRLCDTRTFKCDKVVLSHNQGLYLYKNILAILSVQQQTIHVFQVTPEGTFIDVRTIGRFCYEDDLLTVSAVFPEVQRDSQTGMANPFRDPFINSLKHRLLVYLWRRAEQDGSAMAKRRFFQYFDQLRQLRMWKMQLLDENHLFIKYTSEDVVTLRVTDPSQASFFVVYNMVTTEVIAVFENTSDELLELFENFCDLFRNATLHSEVQFPCSASSNNFARQIQRRFKDTIINAKYGGHTEAVRRLLGQLPISAQSYSGSPYLDLSLFSYDDKWVSVMERPKTCGDHPIRFYARDSGLLKFEIQAGLLGRPINHTVRRLVAFTFHPFEPFAISVQRTNAEYVVNFHMRHCCT", "length": 550 }, "evidence": [ { "id": "F1NZA5", "url": "https://omabrowser.org/oma/group/F1NZA5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VKM4-1", "protein_name": "Abnormal oocyte", "gene_name": "ao", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MAYKKRLQSQNLVHLLQNRESGYTNVGQQPGRMPLLAYERLFYKCITPCLTIDSITIPPIYLRKFTPDGRKLLAFSQDQRSLLIYSYGGSSCAAVGELIRQADVGSGECFSSQDTILKSRIFERLFPTKETLNLCQGDFGLYYLHREFSVFLEEGRYAMLAAMTVVRGALPVDDYVRYPDLFDKVDAFSYVFFLVDLKLGVVTDRLILPNDSIVIAHNHGISVFGSTVMMMSRLHQCVYVYWVNDGKFHQQETIGPRPRDFIEKATTDFDNLDATTVLPITHIKQRVLSFLYRKINDKSGNPTESQKSFYKNFEYIEHMIMERMHLVNNELLMLRYEERPNGTDTMPMATSPRRLYVFYTITGEEVVGVYPEYSVNLLQILLQFNDYMSNDRSLQFGDAPSLPMHFFLRHTFADSNESVSVDRHTALRFNPSVPLSSQSLSSSPYLKFNEFRYDSRYVSPLEQPHRCCNDPIVFLDRATDSIKFRLHATARRHLNPLAPRELCAFIWHPFDPLVLSIQKCMNSYVYHVHLYNHSTIVEK", "length": 539 }, "evidence": [ { "id": "F1NZA5", "url": "https://omabrowser.org/oma/group/F1NZA5/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "Cul4A-RING E3 ubiquitin ligase complex", "id": "GO:0031464", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031464", "evidence": [ { "database": "UniProtKB", "id": "F1NZA5", "url": "https://www.uniprot.org/uniprotkb/F1NZA5" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1NZA5", "url": "https://www.uniprot.org/uniprotkb/F1NZA5" } ], "pmid": "" }, { "name": "cullin-RING ubiquitin ligase complex", "id": "GO:0031461", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031461", "evidence": [ { "database": "UniProtKB", "id": "F1NZA5", "url": "https://www.uniprot.org/uniprotkb/F1NZA5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "ubiquitin protein ligase binding", "id": "GO:0031625", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031625", "evidence": [ { "database": "UniProtKB", "id": "F1NZA5", "url": "https://www.uniprot.org/uniprotkb/F1NZA5" } ], "pmid": "" }, { "name": "protein-containing complex binding", "id": "GO:0044877", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044877", "evidence": [ { "database": "UniProtKB", "id": "F1NZA5", "url": "https://www.uniprot.org/uniprotkb/F1NZA5" } ], "pmid": "" }, { "name": "ubiquitin-like ligase-substrate adaptor activity", "id": "GO:1990756", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990756", "evidence": [ { "database": "UniProtKB", "id": "F1NZA5", "url": "https://www.uniprot.org/uniprotkb/F1NZA5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "F1NZA5", "url": "https://www.uniprot.org/uniprotkb/F1NZA5" } ], "pmid": "" }, { "name": "positive regulation of proteasomal ubiquitin-dependent protein catabolic process", "id": "GO:0032436", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032436", "evidence": [ { "database": "UniProtKB", "id": "F1NZA5", "url": "https://www.uniprot.org/uniprotkb/F1NZA5" } ], "pmid": "" }, { "name": "protein-containing complex assembly", "id": "GO:0065003", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0065003", "evidence": [ { "database": "UniProtKB", "id": "F1NZA5", "url": "https://www.uniprot.org/uniprotkb/F1NZA5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 381, "end_pos": 383, "annotation": "n_glycosylation_sequon" }, { "start_pos": 399, "end_pos": 401, "annotation": "n_glycosylation_sequon" }, { "start_pos": 49, "end_pos": 51, "annotation": "n_glycosylation_sequon" }, { "start_pos": 512, "end_pos": 514, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1NZA5-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 551, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1NZA5-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1NZA5" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 381, "end_pos": 383 }, { "start_pos": 399, "end_pos": 401 }, { "start_pos": 49, "end_pos": 51 }, { "start_pos": 512, "end_pos": 514 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1NVR5-1", "uniprot_ac": "F1NVR5", "uniprot_id": "F1NVR5_CHICK", "mass": { "chemical_mass": 135585.0, "monoisotopic_mass": 135585.0 }, "refseq": { "ac": "XP_419419", "name": "tyrosine-protein phosphatase non-receptor type 14", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_419419" }, "gene_names": [ { "name": "PTPN14", "type": "recommended", "evidence": [ { "id": "F1NVR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NVR5" } ] }, { "name": "PTPN14", "type": "synonym", "evidence": [ { "id": "XP_419419", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_419419" } ] } ], "protein_names": [ { "name": "protein-tyrosine-phosphatase", "type": "recommended", "evidence": [ { "id": "F1NVR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NVR5/entry#names_and_taxonomy" } ] }, { "name": "3.1.3.48", "type": "synonym", "evidence": [ { "id": "F1NVR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NVR5/entry#names_and_taxonomy" } ] }, { "name": "tyrosine-protein phosphatase non-receptor type 14", "type": "synonym", "evidence": [ { "id": "XP_419419", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_419419" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052534.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On May 17, 2018 this sequence version replaced XP_419419.3. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_419419", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_419419" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NVR5", "url": "https://www.uniprot.org/uniprotkb/F1NVR5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PTPN14", "url": "https://www.uniprot.org/uniprotkb/F1NVR5", "locus": { "chromosome": "3", "start_pos": 20855410, "end_pos": 20751564, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010020640", "url": "https://www.ensembl.org/id/ENSGALG00010020640" } ] } } ], "crossref": [ { "id": "F1NVR5", "url": "https://alphafold.ebi.ac.uk/entry/F1NVR5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000009784", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000009784", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd13188", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13188", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd14473", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14473", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd14599", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14599", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd17191", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd17191", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "421360", "url": "https://www.ncbi.nlm.nih.gov/gene/421360", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000242", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000242", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000299", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000299", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000387", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000387", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003595", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003595", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014352", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014352", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014392", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014392", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016130", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016130", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018980", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018980", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019747", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019747", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019748", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019748", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019749", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019749", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029021", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029021", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029071", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029071", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035963", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035963", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041782", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041782", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:421360", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:421360", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "FKKCRQY", "url": "https://omabrowser.org/oma/group/FKKCRQY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z871", "url": "https://www.orthodb.org/?gene=A0A8V0Z871", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZDZ7", "url": "https://www.orthodb.org/?gene=A0A8V0ZDZ7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZFB9", "url": "https://www.orthodb.org/?gene=A0A8V0ZFB9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NVR5", "url": "https://www.orthodb.org/?gene=F1NVR5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45706", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45706", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45706:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45706:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00102", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00102", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00373", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00373", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF09379", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09379", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF09380", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09380", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_419419", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_419419", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "10684", "url": "https://www.rhea-db.org/rhea/10684", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0Z871", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z871", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z871-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z871-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZDZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDZ7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZDZ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDZ7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZFB9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFB9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZFB9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFB9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NVR5", "url": "https://www.uniprot.org/uniprotkb/F1NVR5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NVR5-1", "url": "https://www.uniprot.org/uniprotkb/F1NVR5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPFGLKLRRTRRYNVLSKNCFVTRIRLLDSNVIECTLSVESTGQECLEAVAQRLELRETHYFGLWFLSKSQQARWVELEKPLKKQLDKFANEPLLFFGVMFYVPSVSRLQQEVTRYQYYLQVKKDILDGRLRSSLEQGIRLAGLAVQADFGDYHQFESHDFLREYVLFPMDWTQDEAVLEELTQKVAQEHRTHSGITAAEAELMYINEVERLDGFGQEMFPVKDNHGNDIHLGIFFMGIFIKNRIGRTTVIYRWNDIGNIAHNKSSIVLELINKEENVLFHTDDLENAKYISRLFAARHKFYKQNKICTEQSSSPPPIRRRPTWSRSSLPRQHPFILPPMHVQCGDHYTETHNSQDSIFHGNEETFYCRSQTSLDRCPVDFSYLNGNGPNGSVCSAHSMNSLNRSQNFIQASPMSSNLSIPGSDIMRADYIPSHRHSAIIVPSYRPTPDYETVMRQMKRGVIQMDSQSQSLRNLNIGNTHAYNQPEDLVYSQPEIRERHPYTVTYGPQGGGYNKPVTPSDQMNPNNAVQNKTAASAISHTVSTPELANMQLQSSQNYNTAHMLKNYLFRPPPPYPRPRPATSTPDLASHRHKYVSGSSPDLVTRKVQLSVKTFQEDSSPVVRQSLQEVSEPLLAVKHHAAVNKRHSLEVISNMVRGIEAMALKTLNAPLPRRNTLREQVQPEESVQMGHEVQQVPHYHHKKTFSDATMLIHSSESEEEEETTKSVSQIRALHENMKYSAQLQAALARIPNKPPPEYPGPRKSVSNGALRQDHISASVAVARAKAMRPGPSKAISVSRTDQVAINGSSLGPSISEPDLTSVKERVKKEPVKERPVSEMFSIEDSIIEREIMMRNLEKQKMAGLEAQKRPLMLAALNGLSVARVPVPEDSQDEVAKVPMDERCKILKRKLEEGMVFTEYEQIPKKKADGIFTTAALPENTERNRIREVVPYEENRVELVPTKENNTGYINASHIKVTVGGEEWHYIATQGPLPHTCHDFWQMVWEQGVNVIAMVTAEEEGGRSKSHRYWPKLGSKHSSATYGKFKVTTKFRTDSGCYATTGLKVKHLLSGDEKTVWHLQYTDWPDHGCPDEVQGFLSYLEEIQSVRRHTNSVLDSSNNCNPPIVVHCSAGVGRTGVVILTELMIGCLEHNEKVDVPVMLRHLREQRMFMIQTIAQYKFVYQVLIQFLQNSRLI", "length": 1191, "header": "tr|F1NVR5-1|F1NVR5_CHICK Isoform 1 of protein-tyrosine-phosphatase OS=Gallus gallus OX=9031 GN=PTPN14 PE=3 SV=4 CANONICAL=F1NVR5-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z871-1", "url": "https://www.uniprot.org/uniprotkb/F1NVR5/entry#A0A8V0Z871-1", "sequence": { "sequence": "MPFGLKLRRTRRYNVLSKNCFVTRIRLLDSNVIECTLSVESTGQECLEAVAQRLELRETHYFGLWFLSKSQQARWVELEKPLKKQLDKFANEPLLFFGVMFYVPSVSRLQQEVTRYQYYLQVKKDILDGRLRSSLEQGIRLAGLAVQADFGDYHQFESHDFLREYVLFPMDWTQDEAVLEELTQKVAQEHRTHR", "length": 194, "header": "tr|A0A8V0Z871-1|A0A8V0Z871_CHICK Computationally mapped isoform of Protein tyrosine phosphatase non-receptor type 14 OS=Gallus gallus OX=9031 GN=PTPN14 PE=4 SV=1 CANONICAL=F1NVR5-1" }, "locus": { "chromosome": "3", "start_pos": 20825430, "end_pos": 20788822, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049838.1", "url": "https://www.ensembl.org/id/ENSGALT00010049838.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029442.1", "url": "https://www.ensembl.org/id/ENSGALP00010029442.1" } ] } }, { "isoform_ac": "A0A8V0ZDZ7-1", "url": "https://www.uniprot.org/uniprotkb/F1NVR5/entry#A0A8V0ZDZ7-1", "sequence": { "sequence": "MPFGLKLRRTRRYNVLSKNCFVTRIRLLDSNVIECTLSVESTGQECLEAVAQRLELRETHYFGLWFLSKSQQARWVELEKPLKKQLDKFANEPLLFFGVMFYVPSVSRLQQEVTRYQYYLQVKKDILDGRLRSSLEQGIRLAGLAVQADFGDYHQFESHDFLREYVLFPMDWTQDEAVLEELTQKVAQEHRTHSGITAAEAELMYINEVERLDGFGQEMFPVKDNHGNDIHLGIFFMGIFIKNRIGRTTVIYRWNDIGNIAHNKSSIVLELINKEENVLFHTDDLENAKYISRLFAARHKFYKQNKICTEQSSSPPPIRRRPTWSRSSLPRQHPFILPPMHVQCGDHYTETHNSQDSIFHGNEETFYCRSQTSLDRCPVDFSYLNGNGPNGSVCSAHSMNSLNRSQNFIQASPMSSNLSIPGSDIMRADYIPSHRHSAIIVPSYRPTPDYETVMRQMKRGVIQMDSQSQSLRNLNIGNTHAYNQPEDLVYSQPEIRERHPYTVTYGPQGGGYNKPVTPSDQMNPNNAVQNKTAASAISHTVSTPELANMQLQSSQNYNTAHMLKNYLFRPPPPYPRPRPATSTPDLASHRHKYVSGSSPDLVTRKVQLSVKTFQEDSSPVVRQSLQEVSEPLLAVKHHAAVNKRHSLEVISNMVRGIEAMALKTLNAPLPRRNTLREQVQPEESVQMGHEVQQVPHYHHKKTFSDATMLIHSSESEEEEETTKSVSQIRALHENMKYSAQLQAALARIPNKPPPEYPGPRKSVSNGALRQDHISASVAVARAKAMRPGPSKAISVSRTDQVAINGSSLGPSISEPDLTSVKERVKKEPVKERPVSEMFSIEDSIIEREIMMRNLEKQKMAGLEAQKRPLMLAALNGLSVARVPVPEDSQDEVAKVPMDERCKILKRKLEEGMVFTEYEQIPKKKADGIFTTAALPENTERNRIREVVPYEENRVELVPTKENNTGYINASHIKVTVGGEEWHYIATQGPLPHTCHDFWQMVWEQGVNVIAMVTAEEEGGRSKSHRYWPKLGSKHSSATYGKFKVTTKFRTDSGCYATTGLKVKHLLSGDEKTVWHLQYTDWPDHGCPDEVQGFLSYLEEIQSVRRHTNSVLDSSNNCNPPIVVHCSAGVGRTGVVILTELMIGCLEHNEQFTVL", "length": 1154, "header": "tr|A0A8V0ZDZ7-1|A0A8V0ZDZ7_CHICK Computationally mapped isoform of Tyrosine-protein phosphatase non-receptor type OS=Gallus gallus OX=9031 GN=PTPN14 PE=3 SV=1 CANONICAL=F1NVR5-1" }, "locus": { "chromosome": "3", "start_pos": 20851126, "end_pos": 20788822, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049841.1", "url": "https://www.ensembl.org/id/ENSGALT00010049841.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029444.1", "url": "https://www.ensembl.org/id/ENSGALP00010029444.1" } ] } }, { "isoform_ac": "A0A8V0ZFB9-1", "url": "https://www.uniprot.org/uniprotkb/F1NVR5/entry#A0A8V0ZFB9-1", "sequence": { "sequence": "MNDMDMNCTHYFGLWFLSKSQQARWVELEKPLKKQLDKFANEPLLFFGVMFYVPSVSRLQQEVTRYQYYLQVKKDILDGRLRSSLEQGIRLAGLAVQADFGDYHQFESHDFLREYVLFPMDWTQDEAVLEELTQKVAQEHRTHSGITAAEAELMYINEVERLDGFGQEMFPVKDNHGNDIHLGIFFMGIFIKNRIGRTTVIYRWNDIGNIAHNKSSIVLELINKEENVLFHTDDLENAKYISRLFAARHKFYKQNKICTEQSSSPPPIRRRPTWSRSSLPRQHPFILPPMHVQCGDHYTETHNSQDSIFHGNEETFYCRSQTSLDRCPVDFSYLNGNGPNGSVCSAHSMNSLNRSQNFIQASPMSSNLSIPGSDIMRADYIPSHRHSAIIVPSYRPTPDYETVMRQMKRGVIQMDSQSQSLRNLNIGNTHAYNQPEDLVYSQPEIRERHPYTVTYGPQGGGYNKPVTPSDQMNPNNAVQNKTAASAISHTVSTPELANMQLQSSQNYNTAHMLKNYLFRPPPPYPRPRPATSTPDLASHRHKYVSGSSPDLVTRKVQLSVKTFQEDSSPVVRQSLQEVSEPLLAVKHHAAVNKRHSLEVISNMVRGIEAMALKTLNAPLPRRNTLREQVQPEESVQMGHEVQQVPHYHHKKTFSDATMLIHSSESEEEEETTKSVSQIRALHENMKYSAQLQAALARIPNKPPPEYPGPRKSVSNGALRQDHISASVAVARAKAMRPGPSKAISVSRTDQVAINGSSLGPSISEPDLTSVKERVKKEPVKERPVSEMFSIEDSIIEREIMMRNLEKQKMAGLEAQKRPLMLAALNGLSVARVPVPEDSQDEVAKVPMDERCKILKRKLEEGMVFTEYEQIPKKKADGIFTTAALPENTERNRIREVVPYEENRVELVPTKENNTGYINASHIKVTVGGEEWHYIATQGPLPHTCHDFWQMVWEQGVNVIAMVTAEEEGGRSKSHRYWPKLGSKHSSATYGKFKVTTKFRTDSGCYATTGLKVKHLLSGDEKTVWHLQYTDWPDHGCPDEVQGFLSYLEEIQSVRRHTNSVLDSSNNCNPPIVVHCSAGVGRTGVVILTELMIGCLEHNEKVDVPVMLRHLREQRMFMIQTIAQYKFVYQVLIQFLQNSRLI", "length": 1141, "header": "tr|A0A8V0ZFB9-1|A0A8V0ZFB9_CHICK Computationally mapped isoform of Tyrosine-protein phosphatase non-receptor type OS=Gallus gallus OX=9031 GN=PTPN14 PE=3 SV=1 CANONICAL=F1NVR5-1" }, "locus": { "chromosome": "3", "start_pos": 20854398, "end_pos": 20795159, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049833.1", "url": "https://www.ensembl.org/id/ENSGALT00010049833.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029440.1", "url": "https://www.ensembl.org/id/ENSGALP00010029440.1" } ] } }, { "isoform_ac": "F1NVR5-1", "url": "https://www.uniprot.org/uniprotkb/F1NVR5/entry#F1NVR5-1", "sequence": { "sequence": "MPFGLKLRRTRRYNVLSKNCFVTRIRLLDSNVIECTLSVESTGQECLEAVAQRLELRETHYFGLWFLSKSQQARWVELEKPLKKQLDKFANEPLLFFGVMFYVPSVSRLQQEVTRYQYYLQVKKDILDGRLRSSLEQGIRLAGLAVQADFGDYHQFESHDFLREYVLFPMDWTQDEAVLEELTQKVAQEHRTHSGITAAEAELMYINEVERLDGFGQEMFPVKDNHGNDIHLGIFFMGIFIKNRIGRTTVIYRWNDIGNIAHNKSSIVLELINKEENVLFHTDDLENAKYISRLFAARHKFYKQNKICTEQSSSPPPIRRRPTWSRSSLPRQHPFILPPMHVQCGDHYTETHNSQDSIFHGNEETFYCRSQTSLDRCPVDFSYLNGNGPNGSVCSAHSMNSLNRSQNFIQASPMSSNLSIPGSDIMRADYIPSHRHSAIIVPSYRPTPDYETVMRQMKRGVIQMDSQSQSLRNLNIGNTHAYNQPEDLVYSQPEIRERHPYTVTYGPQGGGYNKPVTPSDQMNPNNAVQNKTAASAISHTVSTPELANMQLQSSQNYNTAHMLKNYLFRPPPPYPRPRPATSTPDLASHRHKYVSGSSPDLVTRKVQLSVKTFQEDSSPVVRQSLQEVSEPLLAVKHHAAVNKRHSLEVISNMVRGIEAMALKTLNAPLPRRNTLREQVQPEESVQMGHEVQQVPHYHHKKTFSDATMLIHSSESEEEEETTKSVSQIRALHENMKYSAQLQAALARIPNKPPPEYPGPRKSVSNGALRQDHISASVAVARAKAMRPGPSKAISVSRTDQVAINGSSLGPSISEPDLTSVKERVKKEPVKERPVSEMFSIEDSIIEREIMMRNLEKQKMAGLEAQKRPLMLAALNGLSVARVPVPEDSQDEVAKVPMDERCKILKRKLEEGMVFTEYEQIPKKKADGIFTTAALPENTERNRIREVVPYEENRVELVPTKENNTGYINASHIKVTVGGEEWHYIATQGPLPHTCHDFWQMVWEQGVNVIAMVTAEEEGGRSKSHRYWPKLGSKHSSATYGKFKVTTKFRTDSGCYATTGLKVKHLLSGDEKTVWHLQYTDWPDHGCPDEVQGFLSYLEEIQSVRRHTNSVLDSSNNCNPPIVVHCSAGVGRTGVVILTELMIGCLEHNEKVDVPVMLRHLREQRMFMIQTIAQYKFVYQVLIQFLQNSRLI", "length": 1191, "header": "tr|F1NVR5-1|F1NVR5_CHICK Isoform 1 of protein-tyrosine-phosphatase OS=Gallus gallus OX=9031 GN=PTPN14 PE=3 SV=4 CANONICAL=F1NVR5-1" }, "locus": { "chromosome": "3", "start_pos": 20854398, "end_pos": 20788822, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049843.1", "url": "https://www.ensembl.org/id/ENSGALT00010049843.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029445.1", "url": "https://www.ensembl.org/id/ENSGALP00010029445.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "gga:421360", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:421360", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2K2N0-1", "protein_name": "Tyrosine-protein phosphatase non-receptor type", "gene_name": "Ptpn14", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPFGLKLRRTRRYNVLSKNCFVTRIRLLDSNVIECTLSVESTGQECLEAVAQRLELRETHYFGLWFLSKSQQARWVELEKPLKKHLDKFANEPLLFFGVMFYVPSVSRLQQEATRYQYYLQVKKDVLEGRLRCSLEQVIRLAGLAVQADFGDYNQFDSQEFLREYVLFPMDLAMEEAALEELTQKVAQEHKAHSGILPAEAELMYINEVERLDGFGQEIFPVKDSHGNSMHLGIFFMGIFVRNRIGRQAVIYRWNDIGTVTHSKAAILLELIDKEETALFHTDDIENAKYISRLFTTRHKFYKQNKICTEQSNSPPPIRRQPTWSRSSLPRQQPYILPPMHVQCSEHYSETHTSQDSIFPGNEEALYCNSHNSLDLNYLNGTVTNGSVCSVHSINSLSCSQSFIQASPVSSNLSIPGSDIMRADYIPSHRHSTIIVPSYRPTPDYETVMRQMKRGLLHADSQSRSLRNLNIINTHAYNQPEELVYSQPEMRERHPYTVPYAPQGGYGHKLVSPSDQVNPQNSAMPSKPGAGSISHTVSTPELANMQLQGAQHYSTAHMLKNYLFRPPPPYPRPRPATSTPDLASHRHKYVSGSSPDLVTRKVQLSVKTFQEDSSPVVHQSLQEVSEPLTATKHHGGGGGAVNKRHSLEVMNSMVRGMEAMTLKSLNIPMARRNTLREQGPSEEAGGHDVHGLPQYHHKKTFSDATMLIHSSESEEEEEAPEAAPQIPELREKVEYSAQLQAALARIPSRPPPEYPGPRKSVSNGTLRQDQGTLLPAMARARVLRHGPAKALSVSRAEQLAVNGASLGPSISEPDLTSVKERVKKEPVKERPVSEMFSLEDSIIEREMMIRNLEKQKMTGLQAQKRPLMLAALNGLSVARVSGREDGRHDVTRVPMDERLRALKKKLEDGMVFTEYEQIPNKKANGIFSTATLPENAERSRIREVVPYEENRVELIPTKENNTGYINASHIKVVVGGSEWHYIATQGPLPHTCHDFWQMVWEQGVNVIAMVTAEEEGGRTKSHRYWPKLGSKHSSATYGKFKVTTKFRTDSGCYATTGLKVKHLLSGQERTVWHLQYTDWPHHGCPEDVQGFLSYLEEIQSVRRHTNSVLEGVKTRHPPIVVHCSAGVGRTGVVILSELMIYCLEHNEKVEVPTMLRFLREQRMFMIQTIAQYKFVYQVLVQFLQNSRLI", "length": 1189 }, "evidence": [ { "id": "F1NVR5", "url": "https://omabrowser.org/oma/group/F1NVR5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E1BEZ8-1", "protein_name": "protein-tyrosine-phosphatase", "gene_name": "PTPN14", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MPFGLKLRRTRRYNVLSKNCFVTRIRLLDSSVIECTLSVESTGQECLEAVAQRLELRETHYFGLWFLSKSQQARWVELEKPLKKHLDKFANEPLLFFGVMFYVPNVSWLQQEATRYQYYLQVKKDVLEGRLRCSLEQVIRLAGLAVQADFGDYNQFDSQDFLREYVLFPMDLALEEAVLEELTQKVAQERKAHSGILPAEAELMYINEVERLDGFGQEIFPVKDNHGNSVHLGIFFMGIFVRNRIGRQAVIYRWNDMGNITHNKSTILVELVNKEETALFHTEDIENAKYISRLFATRHKFYKQNKICTEQSNSPPPIRRQPTWSRSSLPRQQPYILPPMHVQCGEHYSETHTSQDSIFHGNEEALYCNSHNSLDLSYLNGTVTNGGSVCSVHSVNSLSCSQSFIQASPVSSNLSIPGSDIMRADYIPSHRHSAIIVPSYRPTPDYETVMRQMKRGVVHTDSQSQSLRNLNIINTHAYNQPEDLVYSQPEMRERHPYTIPYGPQGGYGNKLVSPSDQLNPTNPTVPSKPGGPSAISHTVSTPELANMQLQGAHSYNAAHVLKNYLFRPPPPYPRPRPATSTPDLASHRHKYVSGSSPDLVTRKVQLSVKTFQEDSSPVVHQSLQEVSEPLTATKHHGAVHKRHSLEAMSSMVRGMEAMTLKSLNIPMARRSTLREPGPPEEGPGSHEVPQLPQYHHKKTFSDATMLIHSSESEEEEEEEAPDPVPQIPVLREKVEYSTQLQAALARIPNKPPPEYPGPRKSVSNGALRQDQACLPPAVARARLLRHGPAKAISVSRADQLAVNGASLGPSISEPDLTSVKERVKKEPVKERPVSEMFSLEDSIIEREMMIRNLEKQKMAGLEAQKRPLMLATLNGLSVARGSGREESRVDATRVPMDERFRTLKKKLEEGMVFTEYEQIPKKKANGIFSTAALPENAERSRIREVVPYEENRVELIPTKENNTGYINASHIKVVVGGAEWHYIATQGPLPHTCHDFWQMVWEQGANVIAMVTAEEEGGRTKSHRYWPKLGSKHSSATYGKFKVTTKFRTDSGCYATTGLKVKHLLSGQERTVWHLQYTDWPDHGCPEDVQGFLSYLEEIQSVRRHTNSMLEGTRNLRPPIVVHCSAGVGRTGVVILSELMIYCLEHNEKVEVPMMLRLLREQRMFMIQTIAQYKFVYQVLIQFLQNSRLI", "length": 1190 }, "evidence": [ { "id": "F1NVR5", "url": "https://omabrowser.org/oma/group/F1NVR5/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q15678-1", "protein_name": "Tyrosine-protein phosphatase non-receptor type 14", "gene_name": "PTPN14", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPFGLKLRRTRRYNVLSKNCFVTRIRLLDSNVIECTLSVESTGQECLEAVAQRLELRETHYFGLWFLSKSQQARWVELEKPLKKHLDKFANEPLLFFGVMFYVPNVSWLQQEATRYQYYLQVKKDVLEGRLRCTLDQVIRLAGLAVQADFGDYNQFDSQDFLREYVLFPMDLALEEAVLEELTQKVAQEHKAHSGILPAEAELMYINEVERLDGFGQEIFPVKDNHGNCVHLGIFFMGIFVRNRIGRQAVIYRWNDMGNITHNKSTILVELINKEETALFHTDDIENAKYISRLFATRHKFYKQNKICTEQSNSPPPIRRQPTWSRSSLPRQQPYILPPVHVQCGEHYSETHTSQDSIFHGNEEALYCNSHNSLDLNYLNGTVTNGSVCSVHSVNSLNCSQSFIQASPVSSNLSIPGSDIMRADYIPSHRHSAIIVPSYRPTPDYETVMRQMKRGILHTDSQSQSLRNLNIINTHAYNQPEDLVYSQPEMRERHPYTVPYGPQGVYSNKLVSPSDQRNPKNNVVPSKPGASAISHTVSTPELANMQLQGSHNYSTAHMLKNYLFRPPPPYPRPRPATSTPDLASHRHKYVSGSSPDLVTRKVQLSVKTFQEDSSPVVHQSLQEVSEPLTATKHHGTVNKRHSLEVMNSMVRGMEAMTLKSLHLPMARRNTLREQGPPEEGSGSHEVPQLPQYHHKKTFSDATMLIHSSESEEEEEEAPESVPQIPMLREKMEYSAQLQAALARIPNKPPPEYPGPRKSVSNGALRQDQASLPPAMARARVLRHGPAKAISMSRTDPPAVNGASLGPSISEPDLTSVKERVKKEPVKERPVSEMFSLEDSIIEREMMIRNLEKQKMAGLEAQKRPLMLAALNGLSVARVSGREENRVDATRVPMDERFRTLKKKLEEGMVFTEYEQIPKKKANGIFSTAALPENAERSRIREVVPYEENRVELIPTKENNTGYINASHIKVVVGGAEWHYIATQGPLPHTCHDFWQMVWEQGVNVIAMVTAEEEGGRTKSHRYWPKLGSKHSSATYGKFKVTTKFRTDSVCYATTGLKVKHLLSGQERTVWHLQYTDWPDHGCPEDVQGFLSYLEEIQSVRRHTNSMLEGTKNRHPPIVVHCSAGVGRTGVLILSELMIYCLEHNEKVEVPMMLRLLREQRMFMIQTIAQYKFVYQVLIQFLQNSRLI", "length": 1187 }, "evidence": [ { "id": "F1NVR5", "url": "https://omabrowser.org/oma/group/F1NVR5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q62130-1", "protein_name": "Tyrosine-protein phosphatase non-receptor type 14", "gene_name": "Ptpn14", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPFGLKLRRTRRYNVLSKNCFVTRIRLLDSNVIECTLSVESTGQECLEAVAQRLELRETHYFGLWFLSKSQQARWVELEKPLKKHLDKFANEPLLFFGVMFYVPNVSRLQQEATRYQYYLQVKKDVLEGRLRCSLEQVIRLAGLAVQADFGDYNQFDSQEFLREYVLFPMDLAMEEAALEELTQKVAQEHKAHSGILPAEAELMYINEVERLDGFGQEIFPVKDSHGNSVHLGIFFMGIFVRNRVGRQAVIYRWNDIGSVTHSKAAILLELIDKEETALFHTDDIENAKYISRLFTTRHKFYKQNKICTEQSNSPPPIRRQPTWSRSSLPRQQPYILPPMHVQCSEHYSETHTSQDSIFPGNEEALYCRSHNSLDLNYLNGTVTNGSVCSVHSVNSLSCSQSFIQASPVSSNLSIPGSDIMRADYIPSHRHSTIIVPSYRPTPDYETVMRQMKRGLMHADSQSRSLRNLNIINTHAYNQPEELVYSQPEMRERHPYTVPYAHQGCYGHKLVSPSDQMNPQNCAMPIKPGASSISHTVSTPELANMQLQGAQHYSTAHMLKNYLFRPPPPYPRPRPATSTPDLASHRHKYVSGSSPDLVTRKVQLSVKTFQEDSSPVVHQSLQEVSEPLTATKHHGGGGGTVNKRHSLEVMNSMVRGMEAMTLKSLNIPMARRNTLREQGPSEETGGHEVHGLPQYHHKKTFSDATMLIHSSESEEEEETLEAAPQVPVLREKVEYSAQLQAALARIPNRPPPEYPGPRKSVSNGALRQDQGTPLPAMARCRVLRHGPSKALSVSRAEQLAVNGASLGPSISEPDLTSVKERVKKEPVKERPVSEMFSLEDSIIEREMMIRNLEKQKMTGPQAQKRPLMLAALNGLSVARVSGREDGHHDATRVPIDERLRALKKKLEDGMVFTEYEQIPNKKANGVFSTATLPENAERSRIREVVPYEENRVELIPTKENNTGYINASHIKVVVGGSEWHYIATQGPLPHTCHDFWQMVWEQGVNVIAMVTAEEEGGRTKSHRYWPKLGSKHSSATYGKFKVTTKFRTDSGCYATTGLKVKHLLSGQERTVWHLQYTDWPHHGCPEDVQGFLSYLEEIQSVRRHTNSVLEGIRTRHPPIVVHCSAGVGRTGVVILSELMIYCLEHNEKVEVPTMLRFLREQRMFMIQTIAQYKFVYQVLVQFLQNSRLI", "length": 1189 }, "evidence": [ { "id": "F1NVR5", "url": "https://omabrowser.org/oma/group/F1NVR5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "F1NVR5", "url": "https://www.uniprot.org/uniprotkb/F1NVR5" } ], "pmid": "" }, { "name": "receptor tyrosine kinase binding", "id": "GO:0030971", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030971", "evidence": [ { "database": "UniProtKB", "id": "F1NVR5", "url": "https://www.uniprot.org/uniprotkb/F1NVR5" } ], "pmid": "" }, { "name": "transcription coregulator activity", "id": "GO:0003712", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003712", "evidence": [ { "database": "UniProtKB", "id": "F1NVR5", "url": "https://www.uniprot.org/uniprotkb/F1NVR5" } ], "pmid": "" }, { "name": "protein tyrosine phosphatase activity", "id": "GO:0004725", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004725", "evidence": [ { "database": "UniProtKB", "id": "F1NVR5", "url": "https://www.uniprot.org/uniprotkb/F1NVR5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "F1NVR5", "url": "https://www.uniprot.org/uniprotkb/F1NVR5" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1NVR5", "url": "https://www.uniprot.org/uniprotkb/F1NVR5" } ], "pmid": "" }, { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "F1NVR5", "url": "https://www.uniprot.org/uniprotkb/F1NVR5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "negative regulation of cell population proliferation", "id": "GO:0008285", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008285", "evidence": [ { "database": "UniProtKB", "id": "F1NVR5", "url": "https://www.uniprot.org/uniprotkb/F1NVR5" } ], "pmid": "" }, { "name": "lymphangiogenesis", "id": "GO:0001946", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001946", "evidence": [ { "database": "UniProtKB", "id": "F1NVR5", "url": "https://www.uniprot.org/uniprotkb/F1NVR5" } ], "pmid": "" }, { "name": "regulation of protein export from nucleus", "id": "GO:0046825", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046825", "evidence": [ { "database": "UniProtKB", "id": "F1NVR5", "url": "https://www.uniprot.org/uniprotkb/F1NVR5" } ], "pmid": "" }, { "name": "positive regulation of hippo signaling", "id": "GO:0035332", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035332", "evidence": [ { "database": "UniProtKB", "id": "F1NVR5", "url": "https://www.uniprot.org/uniprotkb/F1NVR5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 263, "end_pos": 265, "annotation": "n_glycosylation_sequon" }, { "start_pos": 390, "end_pos": 392, "annotation": "n_glycosylation_sequon" }, { "start_pos": 403, "end_pos": 405, "annotation": "n_glycosylation_sequon" }, { "start_pos": 417, "end_pos": 419, "annotation": "n_glycosylation_sequon" }, { "start_pos": 530, "end_pos": 532, "annotation": "n_glycosylation_sequon" }, { "start_pos": 804, "end_pos": 806, "annotation": "n_glycosylation_sequon" }, { "start_pos": 962, "end_pos": 964, "annotation": "n_glycosylation_sequon" }, { "start_pos": 968, "end_pos": 970, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "10684", "name": "", "equation": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A1D5PI23-1", "F1P225-1", "A0A8V0XA98-1", "A0A8V0X472-1", "A0A8V0XI03-1", "A0A1D5P5S2-1", "A0A1D5PC43-1", "P0C597-1", "Q5F4B1-1", "Q6YI48-1", "Q90687-1", "Q98936-1", "Q9PW71-1", "A0A8V0YWD3-1", "A0A8V0Y719-1", "A0A8V0Z2T2-1", "A0A8V0Z920-1", "A0A8V0ZLS3-1", "A0A8V0YHN7-1", "A0A8V0X4H3-1", "Q5ZKG5-1", "Q9YH99-1", "Q9YHA0-1", "F1NCC5-1", "F1NAX3-1", "A0A8V0X8Q6-1", "A0A3Q2TZZ7-1", "A0A1D5NXI7-1", "A0A8V0YAF3-1", "A0A8V0XYX4-1", "A0A8V0YFZ7-1", "A0A8V0XVI4-1", "A0A8V0YFC8-1", "A0A8V0YAP9-1", "A0A8V0YVP7-1", "A0A8V0YIN5-1", "A0A8V0ZMU4-1", "A0A8V0ZPJ8-1", "F1NVR5-1", "A0A8V0ZVG8-1", "A0A8V0ZH43-1", "A0A8V0ZVC2-1", "A0A8V0ZQ53-1", "A0A1D5P6Q1-1", "Q9YH98-1", "A0A8V1A896-1", "A0A8V1AB05-1", "A0A3Q2UCN1-1", "A0A8V1A4B8-1", "A0A8V0ZJ28-1", "F1NWE3-1", "O13016-1", "Q9W6V5-1", "E1BRQ8-1", "A0A1D5P6X3-1", "A0A8V0XAP8-1", "A0A1D5PMZ4-1", "F1N842-1", "A0A8V0YC26-1", "A0A8V0ZXB3-1" ], "evidence": [ { "id": "10684", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/10684" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A1D5NXI7", "gene_name": "EYA4", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A1D5NXI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NXI7" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A1D5NXI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NXI7" } ] } ] }, { "uniprot_ac": "A0A1D5P5S2", "gene_name": "DUSP5", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A1D5P5S2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P5S2" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A1D5P5S2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P5S2" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A1D5P5S2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P5S2" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A1D5P5S2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P5S2" } ] } ] }, { "uniprot_ac": "A0A1D5P6Q1", "gene_name": "PTPN21", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A1D5P6Q1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P6Q1" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A1D5P6Q1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P6Q1" } ] } ] }, { "uniprot_ac": "A0A1D5P6X3", "gene_name": "UBASH3B", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A1D5P6X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P6X3" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A1D5P6X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P6X3" } ] } ] }, { "uniprot_ac": "A0A1D5PC43", "gene_name": "EYA2", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A1D5PC43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PC43" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A1D5PC43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PC43" } ] } ] }, { "uniprot_ac": "A0A1D5PI23", "gene_name": "DUSP3", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A1D5PI23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PI23" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A1D5PI23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PI23" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A1D5PI23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PI23" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A1D5PI23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PI23" } ] } ] }, { "uniprot_ac": "A0A1D5PMZ4", "gene_name": "PTP4A3", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A1D5PMZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PMZ4" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A1D5PMZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PMZ4" } ] } ] }, { "uniprot_ac": "A0A3Q2TZZ7", "gene_name": "PTPRF", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3Q2TZZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TZZ7" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A3Q2TZZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TZZ7" } ] } ] }, { "uniprot_ac": "A0A3Q2UCN1", "gene_name": "PTPN6", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3Q2UCN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UCN1" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A3Q2UCN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UCN1" } ] } ] }, { "uniprot_ac": "A0A8V0X472", "gene_name": "PTPRM", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0X472", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X472" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0X472", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X472" } ] } ] }, { "uniprot_ac": "A0A8V0X4H3", "gene_name": "PTPN2", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0X4H3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X4H3" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0X4H3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X4H3" } ] } ] }, { "uniprot_ac": "A0A8V0X8Q6", "gene_name": "EYA1", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0X8Q6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X8Q6" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0X8Q6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X8Q6" } ] } ] }, { "uniprot_ac": "A0A8V0XA98", "gene_name": "PTPRZ1", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0XA98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XA98" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0XA98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XA98" } ] } ] }, { "uniprot_ac": "A0A8V0XAP8", "gene_name": "PTPN13", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0XAP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XAP8" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0XAP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XAP8" } ] } ] }, { "uniprot_ac": "A0A8V0XI03", "gene_name": "PTPRK", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0XI03", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XI03" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0XI03", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XI03" } ] } ] }, { "uniprot_ac": "A0A8V0XVI4", "gene_name": "LOC100858919", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0XVI4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XVI4" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0XVI4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XVI4" } ] } ] }, { "uniprot_ac": "A0A8V0XYX4", "gene_name": "DUSP1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0XYX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XYX4" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0XYX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XYX4" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0XYX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XYX4" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0XYX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XYX4" } ] } ] }, { "uniprot_ac": "A0A8V0Y719", "gene_name": "PTPN3", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0Y719", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y719" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0Y719", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y719" } ] } ] }, { "uniprot_ac": "A0A8V0YAF3", "gene_name": "PTPN12", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0YAF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAF3" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0YAF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAF3" } ] } ] }, { "uniprot_ac": "A0A8V0YAP9", "gene_name": "EYA3", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0YAP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAP9" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0YAP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAP9" } ] } ] }, { "uniprot_ac": "A0A8V0YC26", "gene_name": "DUSP19", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0YC26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC26" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0YC26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC26" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0YC26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC26" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0YC26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC26" } ] } ] }, { "uniprot_ac": "A0A8V0YFC8", "gene_name": "PTPRC", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0YFC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFC8" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0YFC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFC8" } ] } ] }, { "uniprot_ac": "A0A8V0YFZ7", "gene_name": "PTPRD", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0YFZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFZ7" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0YFZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFZ7" } ] } ] }, { "uniprot_ac": "A0A8V0YHN7", "gene_name": "PTPN1", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0YHN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHN7" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0YHN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHN7" } ] } ] }, { "uniprot_ac": "A0A8V0YIN5", "gene_name": "PTPRB", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0YIN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIN5" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0YIN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIN5" } ] } ] }, { "uniprot_ac": "A0A8V0YVP7", "gene_name": "PTPRU", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0YVP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YVP7" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0YVP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YVP7" } ] } ] }, { "uniprot_ac": "A0A8V0YWD3", "gene_name": "PTPRA", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0YWD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YWD3" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0YWD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YWD3" } ] } ] }, { "uniprot_ac": "A0A8V0Z2T2", "gene_name": "DUSP26", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0Z2T2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2T2" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0Z2T2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2T2" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0Z2T2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2T2" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0Z2T2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2T2" } ] } ] }, { "uniprot_ac": "A0A8V0Z920", "gene_name": "PTPN4", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0Z920", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z920" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0Z920", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z920" } ] } ] }, { "uniprot_ac": "A0A8V0ZH43", "gene_name": "PTPRG", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZH43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH43" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0ZH43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH43" } ] } ] }, { "uniprot_ac": "A0A8V0ZJ28", "gene_name": "PTEN", "activity": [ { "ec_number": "3.1.3.67", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + H2O = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + phosphate.", "evidence": [ { "id": "A0A8V0ZJ28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ28" } ] }, { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZJ28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ28" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZJ28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ28" } ] }, { "ec_number": "3.1.3.67", "activity": "", "evidence": [ { "id": "A0A8V0ZJ28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ28" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0ZJ28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ28" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0ZJ28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ28" } ] } ] }, { "uniprot_ac": "A0A8V0ZLS3", "gene_name": "LOC419429", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZLS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLS3" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0ZLS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLS3" } ] } ] }, { "uniprot_ac": "A0A8V0ZMU4", "gene_name": "DUSP13", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZMU4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMU4" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZMU4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMU4" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0ZMU4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMU4" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0ZMU4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMU4" } ] } ] }, { "uniprot_ac": "A0A8V0ZPJ8", "gene_name": "LOC100857573", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZPJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPJ8" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZPJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPJ8" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0ZPJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPJ8" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0ZPJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPJ8" } ] } ] }, { "uniprot_ac": "A0A8V0ZQ53", "gene_name": "DUSP29", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZQ53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ53" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZQ53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ53" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0ZQ53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ53" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0ZQ53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ53" } ] } ] }, { "uniprot_ac": "A0A8V0ZVC2", "gene_name": "PTPRJ", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZVC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVC2" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0ZVC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVC2" } ] } ] }, { "uniprot_ac": "A0A8V0ZVG8", "gene_name": "PTPRT", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZVG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVG8" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0ZVG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVG8" } ] } ] }, { "uniprot_ac": "A0A8V0ZXB3", "gene_name": "DUSP28", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZXB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXB3" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZXB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXB3" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0ZXB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXB3" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0ZXB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXB3" } ] } ] }, { "uniprot_ac": "A0A8V1A4B8", "gene_name": "PTPRVP", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V1A4B8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4B8" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V1A4B8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4B8" } ] } ] }, { "uniprot_ac": "A0A8V1A896", "gene_name": "CDC25A", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V1A896", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A896" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V1A896", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A896" } ] } ] }, { "uniprot_ac": "A0A8V1AB05", "gene_name": "PTPRS", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V1AB05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AB05" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V1AB05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AB05" } ] } ] }, { "uniprot_ac": "E1BRQ8", "gene_name": "DUSP15", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "E1BRQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BRQ8" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "E1BRQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BRQ8" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "E1BRQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BRQ8" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "E1BRQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BRQ8" } ] } ] }, { "uniprot_ac": "F1N842", "gene_name": "DUSP12", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F1N842", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N842" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1N842", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N842" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "F1N842", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N842" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1N842", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N842" } ] } ] }, { "uniprot_ac": "F1NAX3", "gene_name": "PGP", "activity": [ { "ec_number": "3.1.3.21", "activity": "sn-glycerol 1-phosphate + H2O = glycerol + phosphate.", "evidence": [ { "id": "F1NAX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NAX3" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1NAX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NAX3" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1NAX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NAX3" } ] }, { "ec_number": "3.1.3.21", "activity": "", "evidence": [ { "id": "F1NAX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NAX3" } ] } ] }, { "uniprot_ac": "F1NCC5", "gene_name": "DUSP4", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F1NCC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCC5" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1NCC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCC5" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1NCC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCC5" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "F1NCC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCC5" } ] } ] }, { "uniprot_ac": "F1NVR5", "gene_name": "PTPN14", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1NVR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NVR5" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1NVR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NVR5" } ] } ] }, { "uniprot_ac": "F1NWE3", "gene_name": "PTPRS", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1NWE3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NWE3" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1NWE3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NWE3" } ] } ] }, { "uniprot_ac": "F1P225", "gene_name": "LOC423731", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F1P225", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P225" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1P225", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P225" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1P225", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P225" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "F1P225", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P225" } ] } ] }, { "uniprot_ac": "O13016", "gene_name": "PTPN1", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "O13016", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O13016" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "O13016", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O13016" } ] } ] }, { "uniprot_ac": "P0C597", "gene_name": "DUSP29", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P0C597", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P0C597" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P0C597", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P0C597" } ] } ] }, { "uniprot_ac": "Q5F4B1", "gene_name": "PGP", "activity": [ { "ec_number": "3.1.3.21", "activity": "sn-glycerol 1-phosphate + H2O = glycerol + phosphate.", "evidence": [ { "id": "Q5F4B1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F4B1" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q5F4B1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F4B1" } ] }, { "ec_number": "3.1.3.18", "activity": "2-phosphoglycolate + H2O = glycolate + phosphate.", "evidence": [ { "id": "Q5F4B1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F4B1" } ] }, { "ec_number": "3.1.3.18", "activity": "", "evidence": [ { "id": "Q5F4B1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F4B1" } ] } ] }, { "uniprot_ac": "Q5ZKG5", "gene_name": "ACP1", "activity": [ { "ec_number": "3.1.3.2", "activity": "a phosphate monoester + H2O = an alcohol + phosphate.", "evidence": [ { "id": "Q5ZKG5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKG5" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q5ZKG5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKG5" } ] }, { "ec_number": "3.1.3.2", "activity": "", "evidence": [ { "id": "Q5ZKG5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKG5" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q5ZKG5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKG5" } ] } ] }, { "uniprot_ac": "Q6YI48", "gene_name": "PTPRU", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q6YI48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6YI48" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q6YI48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6YI48" } ] } ] }, { "uniprot_ac": "Q90687", "gene_name": "PTPN11", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q90687", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q90687" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q90687", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q90687" } ] } ] }, { "uniprot_ac": "Q98936", "gene_name": "PTPRG", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q98936", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q98936" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q98936", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q98936" } ] } ] }, { "uniprot_ac": "Q9PW71", "gene_name": "DUSP4", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q9PW71", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9PW71" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q9PW71", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9PW71" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q9PW71", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9PW71" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q9PW71", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9PW71" } ] } ] }, { "uniprot_ac": "Q9W6V5", "gene_name": "PTPRJ", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q9W6V5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W6V5" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q9W6V5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W6V5" } ] } ] }, { "uniprot_ac": "Q9YH98", "gene_name": "EYA4", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q9YH98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9YH98" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q9YH98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9YH98" } ] } ] }, { "uniprot_ac": "Q9YH99", "gene_name": "EYA3", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q9YH99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9YH99" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q9YH99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9YH99" } ] } ] }, { "uniprot_ac": "Q9YHA0", "gene_name": "EYA1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q9YHA0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9YHA0" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q9YHA0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9YHA0" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q9YHA0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9YHA0" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q9YHA0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9YHA0" } ] } ] } ], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1NVR5-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 1191, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1NVR5-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1NVR5" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1NVR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NVR5" }, { "id": "PS50057", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50057" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "FERM", "eco_id": "ECO_0000259", "start_pos": 21, "end_pos": 306, "start_aa": "Phe", "end_aa": "Lys", "glycosite_overlap": "" }, { "evidence": [ { "id": "F1NVR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NVR5" }, { "id": "PS50056", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50056" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Tyrosine specific protein phosphatases", "eco_id": "ECO_0000259", "start_pos": 1094, "end_pos": 1175, "start_aa": "Leu", "end_aa": "Lys", "glycosite_overlap": "" }, { "evidence": [ { "id": "F1NVR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NVR5" }, { "id": "PS50055", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50055" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Tyrosine-protein phosphatase", "eco_id": "ECO_0000259", "start_pos": 913, "end_pos": 1184, "start_aa": "Val", "end_aa": "Phe", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "3.1.3.48", "ec_name": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "3.1.3.48", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.48" }, { "id": "3.1.3.48", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=3.1.3.48" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 263, "end_pos": 265 }, { "start_pos": 390, "end_pos": 392 }, { "start_pos": 403, "end_pos": 405 }, { "start_pos": 417, "end_pos": 419 }, { "start_pos": 530, "end_pos": 532 }, { "start_pos": 804, "end_pos": 806 }, { "start_pos": 962, "end_pos": 964 }, { "start_pos": 968, "end_pos": 970 } ] }, "class_list": [], "section_stats": [ { 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"sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1NXH1-1", "uniprot_ac": "F1NXH1", "uniprot_id": "F1NXH1_CHICK", "mass": { "chemical_mass": 37414.0, "monoisotopic_mass": 37414.0 }, "refseq": { "ac": "NP_001269310", "name": "mitochondrial amidoxime-reducing component 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001269310" }, "gene_names": [ { "name": "MTARC1", "type": "recommended", "evidence": [ { "id": "F1NXH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NXH1" } ] }, { "name": "MARC1", "type": "synonym", "evidence": [ { "id": "NP_001269310", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001269310" } ] }, { "name": "MARC2", "type": "synonym", "evidence": [ { "id": "NP_001269310", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001269310" } ] }, { "name": "MOSC2", "type": "synonym", "evidence": [ { "id": "NP_001269310", "database": "RefSeq", "url": 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"RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001269310" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: SRR13267654.122810.1, SRR12888520.26852.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992323, SAMEA103992393 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: inferred from homology ##RefSeq-Attributes-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000062.1, BM487952.1, CR524133.1, AL584998.1, CN220815.1 and CF257490.1. On Sep 5, 2013 this sequence version replaced XP_426119.3. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001269310", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001269310" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NXH1", "url": "https://www.uniprot.org/uniprotkb/F1NXH1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MTARC1", "url": "https://www.uniprot.org/uniprotkb/F1NXH1", "locus": { "chromosome": "3", "start_pos": 18314032, "end_pos": 18327402, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010017642", "url": "https://www.ensembl.org/id/ENSGALG00010017642" } ] } } ], "crossref": [ { "id": "F1NXH1", "url": "https://alphafold.ebi.ac.uk/entry/F1NXH1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000009453", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000009453", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "428563", "url": "https://www.ncbi.nlm.nih.gov/gene/428563", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR005302", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005302", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005303", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005303", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011037", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011037", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:428563", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:428563", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "AHDRSFM", "url": "https://omabrowser.org/oma/group/AHDRSFM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z9J3", "url": "https://www.orthodb.org/?gene=A0A8V0Z9J3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NXH1", "url": "https://www.orthodb.org/?gene=F1NXH1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14237", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14237", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14237:SF19", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14237:SF19", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03473", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03473", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF03476", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03476", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-211945", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-211945", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001269310", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001269310", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Z9J3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9J3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z9J3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9J3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NXH1", "url": "https://www.uniprot.org/uniprotkb/F1NXH1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NXH1-1", "url": "https://www.uniprot.org/uniprotkb/F1NXH1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MMGAQGLALAAPRGWLWGAAAVAALGVLLGAWRWARGTAAGRRRRRPGRLQRVGTVSSLFVYPVKSCQGVAVQRARVTPMGLQSGEMRDRFWLVVKEDGHMVTARQEPRLVLITTGCENGYLTLSAQGMKKLCLPVKLPSKNPVQNCRVFGLDIQGRDCGDEVAQWITTFLNSEPYRLVHFEPSMVPRKSKDIINLFRTTDEVAYPDCSPLLIISEASLKDLNTRLEKKVKIQNFRPNIFVSDCGAFEEDNWEDILIGDVEMKGTVCCGRCILTTVDPDTGVLDRKEPLETLKSYRLCDPSERHIYKSSPLFGKYFAVDKTGTIQVGDPVYKMIE", "length": 335, "header": "tr|F1NXH1-1|F1NXH1_CHICK Isoform 1 of Mitochondrial amidoxime reducing component 1 OS=Gallus gallus OX=9031 GN=MTARC1 PE=1 SV=2 CANONICAL=F1NXH1-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z9J3-1", "url": "https://www.uniprot.org/uniprotkb/F1NXH1/entry#A0A8V0Z9J3-1", "sequence": { "sequence": "MDLQIEDSSMDSSVAHEEDQGFGGLAYTDGSAVTTSASDVHHIVSFHQQAVTNHNALLPCDTDSSRQECYPVLACDQVHFTRFWLVVKEDGHMVTARQEPRLVLITTGCENGYLTLSAQGMKKLCLPVKLPSKNPVQNCRVFGLDIQGRDCGDEVAQWITTFLNSEPYRLVHFEPSMVPRKSKDIINLFRTTDEVAYPDCSPLLIISEASLKDLNTRLEKKVKIQNFRPNIFVSDCGAFEEDNWEDILIGDVEMKGTVCCGRCILTTVDPDTGVLDRKEPLETLKSYRLCDPSERHIYKSSPLFGKYFAVDKTGTIQVGDPVYKMIE", "length": 327, "header": "tr|A0A8V0Z9J3-1|A0A8V0Z9J3_CHICK Computationally mapped isoform of Mitochondrial amidoxime reducing component 1 OS=Gallus gallus OX=9031 GN=MTARC1 PE=1 SV=1 CANONICAL=F1NXH1-1" }, "locus": { "chromosome": "3", "start_pos": 18325924, "end_pos": 18317103, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042635.1", "url": "https://www.ensembl.org/id/ENSGALT00010042635.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025125.1", "url": "https://www.ensembl.org/id/ENSGALP00010025125.1" } ] } }, { "isoform_ac": "F1NXH1-1", "url": "https://www.uniprot.org/uniprotkb/F1NXH1/entry#F1NXH1-1", "sequence": { "sequence": "MMGAQGLALAAPRGWLWGAAAVAALGVLLGAWRWARGTAAGRRRRRPGRLQRVGTVSSLFVYPVKSCQGVAVQRARVTPMGLQSGEMRDRFWLVVKEDGHMVTARQEPRLVLITTGCENGYLTLSAQGMKKLCLPVKLPSKNPVQNCRVFGLDIQGRDCGDEVAQWITTFLNSEPYRLVHFEPSMVPRKSKDIINLFRTTDEVAYPDCSPLLIISEASLKDLNTRLEKKVKIQNFRPNIFVSDCGAFEEDNWEDILIGDVEMKGTVCCGRCILTTVDPDTGVLDRKEPLETLKSYRLCDPSERHIYKSSPLFGKYFAVDKTGTIQVGDPVYKMIE", "length": 335, "header": "tr|F1NXH1-1|F1NXH1_CHICK Isoform 1 of Mitochondrial amidoxime reducing component 1 OS=Gallus gallus OX=9031 GN=MTARC1 PE=1 SV=2 CANONICAL=F1NXH1-1" }, "locus": { "chromosome": "3", "start_pos": 18323643, "end_pos": 18317103, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042633.1", "url": "https://www.ensembl.org/id/ENSGALT00010042633.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025123.1", "url": "https://www.ensembl.org/id/ENSGALP00010025123.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:428563", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:428563", "resource": "KEGG Pathway" }, { "id": "R-GGA-211945", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-211945", "resource": "Reactome", "description": "Phase I - Functionalization of compounds" } ], "orthologs": [ { "uniprot_canonical_ac": "A1Z803-1", "protein_name": "1.7.-.-", "gene_name": "Marc", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MATGGNNSTFDLSPKTLAAVGVGLVAVGGASFLLYRHLTRDVVPQKWRRVGTVERIHFFPVKSCAPMDISKPGVEYDCDVLSMSFEGIRDRTLMVVNEKNEMITARVYPLMTQIKSKKVSPSKLVFSAQDMPDLELDFEKLDGPGKDVKTSVWGVSIDVMPCGDRINTWFSQAILKKESGLKLVHYPYPKPVRCTNPRLKSMPFIRQEDSGTFNDATSFMLMNLSSVADLNTRLKNPVDALQFRGNFELKMDVDEPYAEDNWQWVRIGEDAVFRTVAPCTRCIFTNINAKTAERSSEGEPLKTLRSYRLFNYSSPALGVHMGLRLPGKVKANDVVYVEDK", "length": 340 }, "evidence": [ { "id": "F1NXH1", "url": "https://omabrowser.org/oma/group/F1NXH1/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "O48588-1", "protein_name": "Molybdenum cofactor sulfurase family protein", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MEEGLKIQSLVIYPIKSCRGISVPQATVTHTGFQWDRYWLVVNYKGRAYTQRVEPTLALVESELPKEAFLEDWEPTNDSLLVIRAPGMSPLKIPLTRPSSVAEGVSMWEWSGSAFDEGEEAAKWFSDYLGKQSRLVRFNKDTETRPSPPEFAAGYSTTFMDMFPFLVASQGSLDHLNTLLPEPVPINRFRPNILVDNCDPFGEDLWDEIKINDLVFQGVRLCSRCKVPTVNQETGVMGKAEPTETLMKFRSDNVLMPDKKPRGKVFFGKEMVWNWNLTNTEGEGKKTIKVGDTISVIRKIPSRAEAAV", "length": 308 }, "evidence": [ { "id": "F1NXH1", "url": "https://omabrowser.org/oma/group/F1NXH1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q1LZH1-1", "protein_name": "Mitochondrial amidoxime reducing component 2", "gene_name": "MTARC2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGAAGSSALARLGLPALPGPRWLGVAALGLAAVALGAVAWRRARPGRRRRLQQVGTVSELWIYPIKSCKGVSVDAAECTALGLRSGHLRDRFWLVIKEDGHMVTGRQEPQLVLVSITYEDDCLILRAPGMDQLVLPTKLLSSNKLHDCRVFGLDIQGRDCGDEAAQWFTSFLKTDAFRLVQFEKNMKARASNEIFPSLDKNYQVAYPDCSPVMILSEASLADLNTRMEKKVKINNFRPNIVVTGCSAFEEDTWDELLIGNVEMKKILACPRCIMTTVDPDTGVIDRKEPLETLKSYRLCDPSEKSIYKSSPLFGIYYSVEKIGSLKVGDPVYQMVQ", "length": 336 }, "evidence": [ { "id": "F1NXH1", "url": "https://omabrowser.org/oma/group/F1NXH1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q8MYE6-1", "protein_name": "Molybdenum cofactor sulfurase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSTNNLLIEFVKSNINFFIGAGILALNAYAFYNNNNLKLDSCSSDQKIKIKKIIIYPIKSCKGIEVKSCKWDKYGFVNDRRFMLIENGRFMTQRKAPKMALIQPNISEDGKWLIIKDKDNTTSELRVLINDTSRKEVINVGIWKDNVNVVDCGEEPSIWFSNYLGIDGVRLVTMASGGSYTRKVDTVYIDKKQQQPEEIHQVSLCDGSQTNILSESSIVELNNRISETRKSNGEEQRSPLTWERFRPNILVSAGDKSFEEDTWEKINISGLVLKKLSAGCPRCKLTTVDYDAGVLNPYDDNEPLRTLETFRKFDSGLLFGAEFIQEFENEANGSEISVGDIINVLKV", "length": 347 }, "evidence": [ { "id": "F1NXH1", "url": "https://omabrowser.org/oma/group/F1NXH1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 6, "go_terms": [ { "name": "molybdenum ion binding", "id": "GO:0030151", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030151", "evidence": [ { "database": "UniProtKB", "id": "F1NXH1", "url": "https://www.uniprot.org/uniprotkb/F1NXH1" } ], "pmid": "" }, { "name": "pyridoxal phosphate binding", "id": "GO:0030170", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030170", "evidence": [ { "database": "UniProtKB", "id": "F1NXH1", "url": "https://www.uniprot.org/uniprotkb/F1NXH1" } ], "pmid": "" }, { "name": "catalytic activity", "id": "GO:0003824", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003824", "evidence": [ { "database": "UniProtKB", "id": "F1NXH1", "url": "https://www.uniprot.org/uniprotkb/F1NXH1" } ], "pmid": "" }, { "name": "nitrate reductase activity", "id": "GO:0008940", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008940", "evidence": [ { "database": "UniProtKB", "id": "F1NXH1", "url": "https://www.uniprot.org/uniprotkb/F1NXH1" } ], "pmid": "" }, { "name": "molybdopterin cofactor binding", "id": "GO:0043546", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043546", "evidence": [ { "database": "UniProtKB", "id": "F1NXH1", "url": "https://www.uniprot.org/uniprotkb/F1NXH1" } ], "pmid": "" }, { "name": "nitrite reductase activity", "id": "GO:0098809", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098809", "evidence": [ { "database": "UniProtKB", "id": "F1NXH1", "url": "https://www.uniprot.org/uniprotkb/F1NXH1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "F1NXH1", "url": "https://www.uniprot.org/uniprotkb/F1NXH1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "nitric oxide biosynthetic process", "id": "GO:0006809", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006809", "evidence": [ { "database": "UniProtKB", "id": "F1NXH1", "url": "https://www.uniprot.org/uniprotkb/F1NXH1" } ], "pmid": "" }, { "name": "nitrate metabolic process", "id": "GO:0042126", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042126", "evidence": [ { "database": "UniProtKB", "id": "F1NXH1", "url": "https://www.uniprot.org/uniprotkb/F1NXH1" } ], "pmid": "" }, { "name": "cellular detoxification of nitrogen compound", "id": "GO:0070458", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070458", "evidence": [ { "database": "UniProtKB", "id": "F1NXH1", "url": "https://www.uniprot.org/uniprotkb/F1NXH1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1NXH1-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 335, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1NXH1-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1NXH1" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1NV47-1", "uniprot_ac": "F1NV47", "uniprot_id": "F1NV47_CHICK", "mass": { "chemical_mass": 61285.0, "monoisotopic_mass": 61285.0 }, "refseq": { "ac": "XP_015142603", "name": "EH domain-containing protein 4 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015142603" }, "gene_names": [ { "name": "EHD4", "type": "recommended", "evidence": [ { "id": "F1NV47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NV47" } ] }, { "name": "EHD4", "type": "synonym", "evidence": [ { "id": "XP_015142603", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015142603" } ] } ], "protein_names": [ { "name": "EH domain containing 4", "type": "synonym", "evidence": [ { "id": "F1NV47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NV47/entry#names_and_taxonomy" } ] }, { "name": "EH domain-containing protein 4 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015142603", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015142603" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052536.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On May 17, 2018 this sequence version replaced XP_015142603.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015142603", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015142603" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NV47", "url": "https://www.uniprot.org/uniprotkb/F1NV47" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "EHD4", "url": "https://www.uniprot.org/uniprotkb/F1NV47", "locus": { "chromosome": "5", "start_pos": 24823218, "end_pos": 24846920, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010020300", "url": "https://www.ensembl.org/id/ENSGALG00010020300" } ] } } ], "crossref": [ { "id": "F1NV47", "url": "https://alphafold.ebi.ac.uk/entry/F1NV47", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000008950", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000008950", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00052", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00052", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd09913", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09913", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100859860", "url": "https://www.ncbi.nlm.nih.gov/gene/100859860", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000261", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000261", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002048", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002048", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011992", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011992", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018247", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018247", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR030381", "url": "https://www.ebi.ac.uk/interpro/entry/IPR030381", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR031692", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031692", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040990", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040990", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045063", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045063", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ISAKKEM", "url": "https://omabrowser.org/oma/group/ISAKKEM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZDL6", "url": "https://www.orthodb.org/?gene=A0A8V0ZDL6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NV47", "url": "https://www.orthodb.org/?gene=F1NV47", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11216", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11216", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11216:SF57", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11216:SF57", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00350", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00350", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12763", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12763", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16880", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16880", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF18150", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18150", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015142603", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015142603", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZDL6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDL6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZDL6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDL6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NV47", "url": "https://www.uniprot.org/uniprotkb/F1NV47", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NV47-1", "url": "https://www.uniprot.org/uniprotkb/F1NV47-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MFSWLGKQGGGRERGVGGSDVVQTVTGGLRDLYLRKLLPLEEHYRFHEFHSPALEEADFENKPMVLLVGQYSTGKTTFIRYLLEQDFPGMRIGPEPTTDSFIAVMYGESEGSVPGNALVVDPKKPFRKLSRFGNAFLNRFLCSQLPNQVLKSISIIDSPGILSGEKQRISRGYDFCQVLQWFAERVDRIILLFDAHKLDISDEFSEAIKAFRGQDDKIRVVLNKADQVDTQQLMRVYGALMWSLGKVINTPEVLRVYIGSFWAQPLRNTENRRLFEAEAQDLFQDIQSLPQKAAVRKLNDLIKRARLAKVHAYIISYLKKEMPTMFGKENKKKELISRLPEIYSQLQREYHISAGDFPEVRKMQEQLEMCDFTKFHSLKPKLIEAVDNMLANKIASLMNLITQEESNMPTEMVHGGAFDGTMAGPFGQGYGEGAKEGADEDEWVVAKDKPAYDEIFYTLSPINGKISGINAKKEMVTSKLPNSVLGKIWKLADCDGDGMLDEEEFALAKHLIKIKLDGYELPGTLPPHLVPPSHRKPLQTAE", "length": 542, "header": "tr|F1NV47-1|F1NV47_CHICK Isoform 1 of EH domain containing 4 OS=Gallus gallus OX=9031 GN=EHD4 PE=1 SV=4 CANONICAL=F1NV47-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZDL6-1", "url": "https://www.uniprot.org/uniprotkb/F1NV47/entry#A0A8V0ZDL6-1", "sequence": { "sequence": "MLSASHSCFRVAKGATGEENGGVPENKDRHCKYLLEQDFPGMRIGPEPTTDSFIAVMYGESEGSVPGNALVVDPKKPFRKLSRFGNAFLNRFLCSQLPNQVLKSISIIDSPGILSGEKQRISRGYDFCQVLQWFAERVDRIILLFDAHKLDISDEFSEAIKAFRGQDDKIRVVLNKADQVDTQQLMRVYGALMWSLGKVINTPEVLRVYIGSFWAQPLRNTENRRLFEAEAQDLFQDIQSLPQKAAVRKLNDLIKRARLAKVHAYIISYLKKEMPTMFGKENKKKELISRLPEIYSQLQREYHISAGDFPEVRKMQEQLEMCDFTKFHSLKPKLIEAVDNMLANKIASLMNLITQEESNMPTEMVHGGAFDGTMAGPFGQGYGEGAKEGADEDEWVVAKDKPAYDEIFYTLSPINGKISGINAKKEMVTSKLPNSVLGKIWKLADCDGDGMLDEEEFALAKHLIKIKLDGYELPGTLPPHLVPPSHRKPLQTAE", "length": 494, "header": "tr|A0A8V0ZDL6-1|A0A8V0ZDL6_CHICK Computationally mapped isoform of EH domain containing 4 OS=Gallus gallus OX=9031 GN=EHD4 PE=1 SV=1 CANONICAL=F1NV47-1" }, "locus": { "chromosome": "5", "start_pos": 24843448, "end_pos": 24827157, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048985.1", "url": "https://www.ensembl.org/id/ENSGALT00010048985.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028957.1", "url": "https://www.ensembl.org/id/ENSGALP00010028957.1" } ] } }, { "isoform_ac": "F1NV47-1", "url": "https://www.uniprot.org/uniprotkb/F1NV47/entry#F1NV47-1", "sequence": { "sequence": "MFSWLGKQGGGRERGVGGSDVVQTVTGGLRDLYLRKLLPLEEHYRFHEFHSPALEEADFENKPMVLLVGQYSTGKTTFIRYLLEQDFPGMRIGPEPTTDSFIAVMYGESEGSVPGNALVVDPKKPFRKLSRFGNAFLNRFLCSQLPNQVLKSISIIDSPGILSGEKQRISRGYDFCQVLQWFAERVDRIILLFDAHKLDISDEFSEAIKAFRGQDDKIRVVLNKADQVDTQQLMRVYGALMWSLGKVINTPEVLRVYIGSFWAQPLRNTENRRLFEAEAQDLFQDIQSLPQKAAVRKLNDLIKRARLAKVHAYIISYLKKEMPTMFGKENKKKELISRLPEIYSQLQREYHISAGDFPEVRKMQEQLEMCDFTKFHSLKPKLIEAVDNMLANKIASLMNLITQEESNMPTEMVHGGAFDGTMAGPFGQGYGEGAKEGADEDEWVVAKDKPAYDEIFYTLSPINGKISGINAKKEMVTSKLPNSVLGKIWKLADCDGDGMLDEEEFALAKHLIKIKLDGYELPGTLPPHLVPPSHRKPLQTAE", "length": 542, "header": "tr|F1NV47-1|F1NV47_CHICK Isoform 1 of EH domain containing 4 OS=Gallus gallus OX=9031 GN=EHD4 PE=1 SV=4 CANONICAL=F1NV47-1" }, "locus": { "chromosome": "5", "start_pos": 24846869, "end_pos": 24827157, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048990.1", "url": "https://www.ensembl.org/id/ENSGALT00010048990.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028961.1", "url": "https://www.ensembl.org/id/ENSGALP00010028961.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "B3LF48-1", "protein_name": "EH domain-containing protein 2", "gene_name": "EHD2", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "METSSTISIGSCLKEHQKIYKEWFNIADSDGDGRVSGNDATKFFAMSKLSRQELKQVWAVADSKRQGFLGLSEFITAMKLVSLAQEGHEITSDLLKGSIDMKSVELPVLEGLENVVSKQKVSKTNVDVEDNVVTKPQVTAKTPWFKSKSIIKPQVNVVTIVDGLKRLYTEKLKPLEVTYRFNDFASPVLTSSDFDAKPMVMLLGQYSTGKTTFIKHLLGCDYPGAHIGPEPTTDRFVVAMSGPDERTIPGNTMAVQADMPFNGLTSFGGAFLSKFECSQMPHPVLDQITLVDTPGVLSGEKQRMQRSYDFTGVISWFASKCDMILLLFDPHKLDISDEFKRVITSLRGNEDKIRVVLNKADQVDTQQLMRVYGALMWSLGKVLNTPEVVRVYIGSFNDKPINEVAVGPIGKELFEKEQNDLLADLMDVPKKACDRKINEFVKRARSAKINAYIMSHLKKEMPAMMGKSKAQQRLMDNLEEEFGKVQREFHLPAGDFPSVEHFREVLGGYNIDKFEKLKPKMIQAVDDMLGYDIPDLLKKFRNPYDN", "length": 546 }, "evidence": [ { "id": "F1NV47", "url": "https://omabrowser.org/oma/group/F1NV47/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "E1BJV0-1", "protein_name": "EH domain containing 4", "gene_name": "EHD4", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MFSWLGRQAGGRGGTGADPVQTVTGGLRSLYQRKVLPLEEAYRFHEFHSPALEDADFENKPMILLVGQYSTGKTTFIRYLLEQDFPGMRIGPEPTTDSFIAVMYGETEGNTPGNALVVDPKKPFRKLGRFGNAFLNRFMCSQLPNEVLKSISIIDSPGILSGEKQRISRGYDFCQVLQWFAERVDRIILLFDAHKLDISDEFSEAIKAFRGQDDKIRVVLNKADQVDTQQLMRVYGALMWSLGKVINTPEVLRVYIGSFWTQPLQNTDNRRLFEAEAQDLFRDIQSLPQKAAVRKLNDLIKRARLAKVHAYIISFLKKEMPSMFGKENKKRELISRLPEIYIQLQREYHISAGDFPKVKAMQEKLENYDFTKFHSLKPKLIEAVDNMLTNKISSLMNLISQEEMSMPPPLVQGGAFDGTAESPFNQGYGEGAKEGADEEEWVVAKDKPVYDELFYTLSPINGKISGINAKKEMVTSKLPNSVLGKIWKLADCDGDGMLDEEEFALAKHLIKIKLSGYELPSSLPPHLVPPSHRKSLSKAD", "length": 540 }, "evidence": [ { "id": "F1NV47", "url": "https://omabrowser.org/oma/group/F1NV47/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "I3LDA5-1", "protein_name": "EH domain containing 4", "gene_name": "EHD4", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MFSWMGRQAGGRERAGGADAVQTVTGGLRSLYLRKVLPLEEAYRFHEFHSPALEDADFENKPMILLVGQYSTGKTTFIRYLLEQDFPGMRIGPEPTTDSFIAVMYGETEGSTPGNALVVDPKKPFRKLSRFGNAFLNRFMCSQLPNQVLKSISIIDSPGILSGEKQRISRGYDFCQVLQWFAERVDRIILLFDAHKLDISDEFSEAIKAFRGQDDKIRVVLNKADQVDTQQLMRVYGALMWSLGKVINTPEVLRVYIGSFWAQPLQNTDNRRLFEAEAQDLFRDIQSLPQKAAVRKLNDLIKRARLAKVHAYIISYLKKEMPSVFGKENKKRELISRLPEIYIQLQREYQISAGDFPEVKAMQEQLENYDFTKFHSLKPKLIEAVDNMLSSKISSLMSLISQEEMSMPTQLVQGGAFDGTAEGPFNQGYGEGAKEGADEEEWVVAKDKPVYDELFYTLSPVNGKISGVNAKKEMVTSKLPNSVLGKIWKLADCDCDGMLDEEEFALAKHLIKIKLDGYELPNSLPPHLVPPSHRKSLQKAD", "length": 541 }, "evidence": [ { "id": "F1NV47", "url": "https://omabrowser.org/oma/group/F1NV47/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q8R3Z7-1", "protein_name": "EH-domain containing 4", "gene_name": "Ehd4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRKDLRSLLNNERAPVTQRLMIGRCGRGRARERAVARASPAPRVLPLEEAYRFHEFHSPALEDADFENKPMILLVGQYSTGKTTFIRYLLEQDFPGMRIGPEPTTDSFIAVMYGETEGSTPGNALVVDPKKPFRKLSRFGNAFLNRFMCSQLPNQVLKSISIIDSPGILSGEKQRISRGYDFCQVLQWFAERVDRIILLFDAHKLDISDEFSEAIKAFRGQDDKIRVVLNKADQVDTQQLMRVYGALMWSLGKVINTPEVLRVYIGSFWAQPLQNTDNRRLFEAEAQDLFRDIQSLPQKAAVRKLNDLIKRARLAKVHAYIISYLKKEMPSMFGKENKKRELIFRLPEIYVQLQREYQISAGDFPEVKAMQEQLENYDFTKFHSLKPKLIEAVDNMLTNKISSLMSLISQEEMNMPTQMVQGGAFDGTTEGPFNQGYGEGAKEGADEEEWVVAKDKPVYDELFYTLSPINGKISGVNAKKEMVTSKLPNSVLGKIWKLADCDCDGMLDEEEFALAKHLIKIKLDGYELPNSLPPHLVPPSHRKSLPKAD", "length": 549 }, "evidence": [ { "id": "F1NV47", "url": "https://omabrowser.org/oma/group/F1NV47/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9EQP2-1", "protein_name": "EH domain-containing protein 4", "gene_name": "Ehd4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWMGRQAGGRERSGGMDAVQTVTGGLRSLYQRKVLPLEEAYRFHEFHSPALEDADFENKPMILLVGQYSTGKTTFIRYLLEQDFPGMRIGPEPTTDSFIAVMYGETEGSTPGNALVVDPKKPFRKLSRFGNAFLNRFMCSQLPNQVLKSISIIDSPGILSGEKQRISRGYDFCQVLQWFAERVDRIILLFDAHKLDISDEFSEAIKAFRGQDDKIRVVLNKADQVDTQQLMRVYGALMWSLGKVINTPEVLRVYIGSFWAQPLQNTDNRRLFEAEAQDLFRDIQSLPQKAAVRKLNDLIKRARLAKVHAYIISYLKKEMPNMFGKENKKRELIYRLPEIYVQLQREYQISAGDFPEVKAMQEQLENYDFTKFHSLKPKLIEAVDNMLTNKISSLMGLISQEEMNMPTQMVQGGAFDGTTEGPFNQGYGEGAKEGADEEEWVVAKDKPVYDELFYTLSPINGKISGVNAKKEMVTSKLPNSVLGKIWKLADCDCDGMLDEEEFALAKHLIKIKLDGYELPNSLPPHLVPPSHRKSLPKAD", "length": 541 }, "evidence": [ { "id": "F1NV47", "url": "https://omabrowser.org/oma/group/F1NV47/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9H223-1", "protein_name": "EH domain-containing protein 4", "gene_name": "EHD4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MFSWMGRQAGGRERAGGADAVQTVTGGLRSLYLRKVLPLEEAYRFHEFHSPALEDADFENKPMILLVGQYSTGKTTFIRYLLEQDFPGMRIGPEPTTDSFIAVMYGETEGSTPGNALVVDPKKPFRKLSRFGNAFLNRFMCSQLPNQVLKSISVIDSPGILSGEKQRISRGYDFCQVLQWFAERVDRIILLFDAHKLDISDEFSEAIKAFRGQDDKIRVVLNKADQVDTQQLMRVYGALMWSLGKVINTPEVLRVYIGSFWAQPLQNTDNRRLFEAEAQDLFRDIQSLPQKAAVRKLNDLIKRARLAKVHAYIISYLKKEMPSVFGKENKKRELISRLPEIYIQLQREYQISAGDFPEVKAMQEQLENYDFTKFHSLKPKLIEAVDNMLSNKISPLMNLISQEETSTPTQLVQGGAFDGTTEGPFNQGYGEGAKEGADEEEWVVAKDKPVYDELFYTLSPINGKISGVNAKKEMVTSKLPNSVLGKIWKLADCDCDGMLDEEEFALAKHLIKIKLDGYELPSSLPPHLVPPSHRKSLPKAD", "length": 541 }, "evidence": [ { "id": "F1NV47", "url": "https://omabrowser.org/oma/group/F1NV47/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "F1NV47", "url": "https://www.uniprot.org/uniprotkb/F1NV47" } ], "pmid": "" }, { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "F1NV47", "url": "https://www.uniprot.org/uniprotkb/F1NV47" } ], "pmid": "" }, { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "F1NV47", "url": "https://www.uniprot.org/uniprotkb/F1NV47" } ], "pmid": "" }, { "name": "protein-macromolecule adaptor activity", "id": "GO:0030674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030674", "evidence": [ { "database": "UniProtKB", "id": "F1NV47", "url": "https://www.uniprot.org/uniprotkb/F1NV47" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 9, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F1NV47", "url": "https://www.uniprot.org/uniprotkb/F1NV47" } ], "pmid": "" }, { "name": "endosome membrane", "id": "GO:0010008", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010008", "evidence": [ { "database": "UniProtKB", "id": "F1NV47", "url": "https://www.uniprot.org/uniprotkb/F1NV47" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1NV47", "url": "https://www.uniprot.org/uniprotkb/F1NV47" } ], "pmid": "" }, { "name": "early endosome", "id": "GO:0005769", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005769", "evidence": [ { "database": "UniProtKB", "id": "F1NV47", "url": "https://www.uniprot.org/uniprotkb/F1NV47" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "F1NV47", "url": "https://www.uniprot.org/uniprotkb/F1NV47" } ], "pmid": "" }, { "name": "adherens junction", "id": "GO:0005912", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005912", "evidence": [ { "database": "UniProtKB", "id": "F1NV47", "url": "https://www.uniprot.org/uniprotkb/F1NV47" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "F1NV47", "url": "https://www.uniprot.org/uniprotkb/F1NV47" } ], "pmid": "" }, { "name": "recycling endosome membrane", "id": "GO:0055038", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055038", "evidence": [ { "database": "UniProtKB", "id": "F1NV47", "url": "https://www.uniprot.org/uniprotkb/F1NV47" } ], "pmid": "" }, { "name": "endocytic vesicle", "id": "GO:0030139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030139", "evidence": [ { "database": "UniProtKB", "id": "F1NV47", "url": "https://www.uniprot.org/uniprotkb/F1NV47" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "endocytosis", "id": "GO:0006897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006897", "evidence": [ { "database": "UniProtKB", "id": "F1NV47", "url": "https://www.uniprot.org/uniprotkb/F1NV47" } ], "pmid": "" }, { "name": "protein homooligomerization", "id": "GO:0051260", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051260", "evidence": [ { "database": "UniProtKB", "id": "F1NV47", "url": "https://www.uniprot.org/uniprotkb/F1NV47" } ], "pmid": "" }, { "name": "protein localization to plasma membrane", "id": "GO:0072659", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072659", "evidence": [ { "database": "UniProtKB", "id": "F1NV47", "url": "https://www.uniprot.org/uniprotkb/F1NV47" } ], "pmid": "" }, { "name": "cilium assembly", "id": "GO:0060271", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060271", "evidence": [ { "database": "UniProtKB", "id": "F1NV47", "url": "https://www.uniprot.org/uniprotkb/F1NV47" } ], "pmid": "" }, { "name": "endocytic recycling", "id": "GO:0032456", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032456", "evidence": [ { "database": "UniProtKB", "id": "F1NV47", "url": "https://www.uniprot.org/uniprotkb/F1NV47" } ], "pmid": "" }, { "name": "cell migration involved in sprouting angiogenesis", "id": "GO:0002042", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002042", "evidence": [ { "database": "UniProtKB", "id": "F1NV47", "url": "https://www.uniprot.org/uniprotkb/F1NV47" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1NV47-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 542, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1NV47-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1NV47" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1NX13-1", "uniprot_ac": "F1NX13", "uniprot_id": "F1NX13_CHICK", "mass": { "chemical_mass": 40460.0, "monoisotopic_mass": 40460.0 }, "refseq": { "ac": "NP_001027533", "name": "developmentally-regulated GTP-binding protein 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001027533" }, "gene_names": [ { "name": "DRG1", "type": "recommended", "evidence": [ { "id": "F1NX13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NX13" } ] }, { "name": "DRG1", "type": "synonym", "evidence": [ { "id": "NP_001027533", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001027533" } ] } ], "protein_names": [ { "name": "Developmentally-regulated GTP-binding protein 1", "type": "recommended", "evidence": [ { "id": "F1NX13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NX13/entry#names_and_taxonomy" } ] }, { "name": "Gallus gallus drg1 partial fragment", "type": "synonym", "evidence": [ { "id": "NP_001027533", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001027533" } ] }, { "name": "Translation factor GTPase DRG1", "type": "synonym", "evidence": [ { "id": "F1NX13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NX13/entry#names_and_taxonomy" } ] }, { "name": "developmentally-regulated GTP-binding protein 1", "type": "synonym", "evidence": [ { "id": "NP_001027533", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001027533" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: BX929580.2, BX933980.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA103992290, SAMEA103992323 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BQ484506.1, BX933980.1, BU383400.1 and BX936006.2. On May 18, 2006 this sequence version replaced XP_415255.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001027533", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001027533" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NX13", "url": "https://www.uniprot.org/uniprotkb/F1NX13" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "DRG1", "url": "https://www.uniprot.org/uniprotkb/F1NX13", "locus": { "chromosome": "15", "start_pos": 8998932, "end_pos": 9012416, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010022037", "url": "https://www.ensembl.org/id/ENSGALG00010022037" } ] } } ], "crossref": [ { "id": "F1NX13", "url": "https://alphafold.ebi.ac.uk/entry/F1NX13", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000006921", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000006921", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd01896", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01896", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd17230", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd17230", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "416962", "url": "https://www.ncbi.nlm.nih.gov/gene/416962", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004095", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004095", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005225", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005225", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006073", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006073", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006074", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006074", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012676", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012676", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR031167", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031167", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR031662", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031662", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045001", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045001", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:416962", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416962", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "SAKHPGQ", "url": "https://omabrowser.org/oma/group/SAKHPGQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZG43", "url": "https://www.orthodb.org/?gene=A0A8V0ZG43", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NX13", "url": "https://www.orthodb.org/?gene=F1NX13", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR43127", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43127", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01926", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01926", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02824", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02824", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16897", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16897", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-9629569", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9629569", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001027533", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001027533", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZG43", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG43", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZG43-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG43-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NX13", "url": "https://www.uniprot.org/uniprotkb/F1NX13", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NX13-1", "url": "https://www.uniprot.org/uniprotkb/F1NX13-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSGTLAKIAEIEAEMARTQKNKATAHHLGLLKARLAKLRRELITPKGGGGGGPGEGFDVAKTGDARIGFVGFPSVGKSTLLSNLAGVYSEVAAYEFTTLTTVPGVIRYKGAKIQLLDLPGIIEGAKDGKGRGRQVIAVARTCNLILIVLDVLKPLGHKKIIENELEGFGIRLNSKPPNIGFKKKDKGGINLTATCPQSELDAETVKSILAEYKIHNADVTLRSDATADDLIDVVEGNRVYIPCIYVLNKIDQISIEELDIIYKVPHCVPISAHHRWNFDDLLEKIWDYLKLVRIYTKPKGQLPDYTSPVVLPYCKTTVEDFCMKIHKNLIKDFKYALVWGSSVKHNPQKVGKDHTLEDEDVIQIVKK", "length": 367, "header": "tr|F1NX13-1|F1NX13_CHICK Isoform 1 of Developmentally-regulated GTP-binding protein 1 OS=Gallus gallus OX=9031 GN=DRG1 PE=1 SV=1 CANONICAL=F1NX13-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZG43-1", "url": "https://www.uniprot.org/uniprotkb/F1NX13/entry#A0A8V0ZG43-1", "sequence": { "sequence": "MSGTLAKIAEIEAEMARTQKNKATAHHLGLLKARLAKLRRELITPKGGGGGGPGEGFDVAKTGDARIGFVGFPSVGKSTLLSNLAGVYSEVAAYEFTTLTTVPGVIRYKGAKIQLLDLPGIIEGAKDGKGRGRQVIAVARTCNLILIVLDVLKPLGHKKIIENELEGFGIRLNSKPPNIGFKKKDKGGINLTATCPQSELDAETVKSILAEYKIHNADVTLRSDATADDLIDVVEGNRVYIPCIYVLNKIDQISIEELDIIYKVPHCVPISAHHRWNFDDLLEKIWDYLKLVRIYTKPKGQLPDYTSPVVLPYCKTTVEDFCMKIHKNLIKDFK", "length": 334, "header": "tr|A0A8V0ZG43-1|A0A8V0ZG43_CHICK Computationally mapped isoform of Developmentally regulated GTP binding protein 1 OS=Gallus gallus OX=9031 GN=DRG1 PE=1 SV=1 CANONICAL=F1NX13-1" }, "locus": { "chromosome": "15", "start_pos": 9012338, "end_pos": 9008571, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053570.1", "url": "https://www.ensembl.org/id/ENSGALT00010053570.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032280.1", "url": "https://www.ensembl.org/id/ENSGALP00010032280.1" } ] } }, { "isoform_ac": "F1NX13-1", "url": "https://www.uniprot.org/uniprotkb/F1NX13/entry#F1NX13-1", "sequence": { "sequence": "MSGTLAKIAEIEAEMARTQKNKATAHHLGLLKARLAKLRRELITPKGGGGGGPGEGFDVAKTGDARIGFVGFPSVGKSTLLSNLAGVYSEVAAYEFTTLTTVPGVIRYKGAKIQLLDLPGIIEGAKDGKGRGRQVIAVARTCNLILIVLDVLKPLGHKKIIENELEGFGIRLNSKPPNIGFKKKDKGGINLTATCPQSELDAETVKSILAEYKIHNADVTLRSDATADDLIDVVEGNRVYIPCIYVLNKIDQISIEELDIIYKVPHCVPISAHHRWNFDDLLEKIWDYLKLVRIYTKPKGQLPDYTSPVVLPYCKTTVEDFCMKIHKNLIKDFKYALVWGSSVKHNPQKVGKDHTLEDEDVIQIVKK", "length": 367, "header": "tr|F1NX13-1|F1NX13_CHICK Isoform 1 of Developmentally-regulated GTP-binding protein 1 OS=Gallus gallus OX=9031 GN=DRG1 PE=1 SV=1 CANONICAL=F1NX13-1" }, "locus": { "chromosome": "15", "start_pos": 9012338, "end_pos": 9007997, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053568.1", "url": "https://www.ensembl.org/id/ENSGALT00010053568.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032279.1", "url": "https://www.ensembl.org/id/ENSGALP00010032279.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:416962", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416962", "resource": "KEGG Pathway" }, { "id": "R-GGA-9629569", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9629569", "resource": "Reactome", "description": "Protein hydroxylation" } ], "orthologs": [ { "uniprot_canonical_ac": "F1RPB7-1", "protein_name": "Developmentally-regulated GTP-binding protein 1", "gene_name": "DRG1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSSTLAKIAEIEAEMARTQKNKATAHHLGLLKARLAKLRRELITPKGGGGGGPGEGFDVAKTGDARIGFVGFPSVGKSTLLSNLAGVYSEVAAYEFTTLTTVPGVIRYKGAKIQLLDLPGIIEGAKDGKGRGRQVIAVARTCNLILIVLDVLKPLGHKKIIENELEGFGIRLNSKPPNIGFKKKDKGGINLTTTCPQSELDAETVKSILAEYKIHNADVTLRSDATADDLIDVVEGNRVYIPCIYVLNKIDQISIEELDIIYKVPHCVPISAHHRWNFDDLLEKIWDYLKLVRIYTKPKGQLPDYTSPVVLPYSRTTVEDFCMKIHKNLIKEFKYALVWGLSVKHNPQKVGKDHTLEDEDVIQIVKK", "length": 367 }, "evidence": [ { "id": "F1NX13", "url": "https://omabrowser.org/oma/group/F1NX13/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P32233-1", "protein_name": "Developmentally-regulated GTP-binding protein 1", "gene_name": "Drg1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSGTLAKIAEIEAEMARTQKNKATAHHLGLLKARLAKLRRELITPKGGGGGGPGEGFDVAKTGDARIGFVGFPSVGKSTLLSNLAGVYSEVAAYEFTTLTTVPGVIRYKGAKIQLLDLPGIIEGAKDGKGRGRQVIAVARTCNLILIVLDVLKPLGHKKIIENELEGFGIRLNSKPPNIGFKKKDKGGINLTATCPQSELDAETVKSILAEYKIHNADVTLRSDATADDLIDVVEGNRVYIPCIYVLNKIDQISIEELDIIYKVPHCVPISAHHRWNFDDLLEKIWDYLKLVRIYTKPKGQLPDYTSPVVLPYSRTTVEDFCMKIHKNLIKEFKYALVWGLSVKHNPQKVGKDHTLEDEDVIQIVKK", "length": 367 }, "evidence": [ { "id": "F1NX13", "url": "https://omabrowser.org/oma/group/F1NX13/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P32234-1", "protein_name": "Guanylate binding protein 128up", "gene_name": "128up", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSTILEKISAIESEMARTQKNKATSAHLGLLKAKLAKLRRELISPKGGGGGTGEAGFEVAKTGDARVGFVGFPSVGKSTLLSNLAGVYSEVAAYEFTTLTTVPGCIKYKGAKIQLLDLPGIIEGAKDGKGRGRQVIAVARTCNLIFMVLDCLKPLGHKKLLEHELEGFGIRLNKKPPNIYYKRKDKGGINLNSMVPQSELDTDLVKTILSEYKIHNADITLRYDATSDDLIDVIEGNRIYIPCIYLLNKIDQISIEELDVIYKIPHCVPISAHHHWNFDDLLELMWEYLRLQRIYTKPKGQLPDYNSPVVLHNERTSIEDFCNKLHRSIAKEFKYALVWGSSVKHQPQKVGIEHVLNDEDVVQIVKKV", "length": 368 }, "evidence": [ { "id": "F1NX13", "url": "https://omabrowser.org/oma/group/F1NX13/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "P39729-1", "protein_name": "Ribosome-interacting GTPase 1", "gene_name": "RBG1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSTTVEKIKAIEDEMARTQKNKATSFHLGQLKAKLAKLRRELLTSASSGSGGGAGIGFDVARTGVASVGFVGFPSVGKSTLLSKLTGTESEAAEYEFTTLVTVPGVIRYKGAKIQMLDLPGIIDGAKDGRGRGKQVIAVARTCNLLFIILDVNKPLHHKQIIEKELEGVGIRLNKTPPDILIKKKEKGGISITNTVPLTHLGNDEIRAVMSEYRINSAEIAFRCDATVDDLIDVLEASSRRYMPAIYVLNKIDSLSIEELELLYRIPNAVPISSGQDWNLDELLQVMWDRLNLVRIYTKPKGQIPDFTDPVVLRSDRCSVKDFCNQIHKSLVDDFRNALVYGSSVKHQPQYVGLSHILEDEDVVTILKK", "length": 369 }, "evidence": [ { "id": "F1NX13", "url": "https://omabrowser.org/oma/group/F1NX13/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q3MHP5-1", "protein_name": "Developmentally-regulated GTP-binding protein 1", "gene_name": "DRG1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSSTLAKIAEIEAEMARTQKNKATAHHLGLLKARLAKLRRELITPKGGGGGGPGEGFDVAKTGDARIGFVGFPSVGKSTLLSNLAGVYSEVAAYEFTTLTTVPGVIRYKGAKIQLLDLPGIIEGAKDGKGRGRQVIAVARTCNLILIVLDVLKPLGHKKIIENELEGFGIRLNSKPPNIGFKKKDKGGINLTATCPQSELDAETVKSILAEYKIHNADVTLRSDATADDLIDVVEGNRVYIPCIYVLNKIDQISIEELDIIYKVPHCVPISAHHRWNFDDLLEKIWDYLKLVRIYTKPKGQLPDYTSPVVLPYSRTTVEDFCMKIHKNLIKEFKYALVWGLSVKHNPQKVGKDHTLEDEDVIQIVKK", "length": 367 }, "evidence": [ { "id": "F1NX13", "url": "https://omabrowser.org/oma/group/F1NX13/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q54HP3-1", "protein_name": "Developmentally-regulated GTP-binding protein 1 homolog", "gene_name": "drg1", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSLVQKIKEVEDEMARTQKNKATSFHLGVLKAKLAKYKRELLLGPSKGAAAGAGEGFDVSKAGDARVGLIGFPSVGKSTLLTKLTGTSSEVASYEFTTLTCIPGVINYKGAKIQLLDLPGIIEGAKDGKGRGRQVIAVGRTCNLILIVLDAMKPLVHKKIIERELDGFGIRLNKQPPPITFKKKEKGGINFSHTPNVNPTQLDSETVKAICAEYKIHNADVILRGNCTVDEFIDVIEGNRIYVPCIYVLNKIDAISIEELDLLDKIPHYVPISSHLEWNLDALLDKIWEYLKLIRVYTKPKGLIPDYNEPVVIRGGEEASIETFCNHIHNSIIRQFRYALVWGSSAKHNPQRCGKDHVLADEDIVQIVKK", "length": 370 }, "evidence": [ { "id": "F1NX13", "url": "https://omabrowser.org/oma/group/F1NX13/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q9SVA6-1", "protein_name": "Developmentally-regulated G protein 3", "gene_name": "DRG3", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSTIMQKIKEIEDEMAKTQKNKATSHHLGLLKAKLAKLRRDLLAPPTKGGGGGAGEGFDVTKSGDSRVGLVGFPSVGKSTLLNKLTGTFSEVASYEFTTLTCIPGVITYRGAKIQLLDLPGIIEGAKDGKGRGRQVISTARTCNCILIVLDAIKPITHKRLIEKELEGFGIRLNKEPPNLTFRKKDKGGINLTSTVAVTHLDLDTVKAICGEYRMHNADITLRYDATADDLIDVIEGSRIYMPCIYAVNKIDSITLEELEILDKLPHYCPVSAHLEWNLDGLLDKIWEYLDLTRIYTKPKAMNPDYDDPVILSSKKRTVEDFCIRIHKDMLKQFKYALVWGSSAKHKPQRVGKEHELEDEDVVQIVKKI", "length": 369 }, "evidence": [ { "id": "F1NX13", "url": "https://omabrowser.org/oma/group/F1NX13/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9Y295-1", "protein_name": "Developmentally-regulated GTP-binding protein 1", "gene_name": "DRG1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSSTLAKIAEIEAEMARTQKNKATAHHLGLLKARLAKLRRELITPKGGGGGGPGEGFDVAKTGDARIGFVGFPSVGKSTLLSNLAGVYSEVAAYEFTTLTTVPGVIRYKGAKIQLLDLPGIIEGAKDGKGRGRQVIAVARTCNLILIVLDVLKPLGHKKIIENELEGFGIRLNSKPPNIGFKKKDKGGINLTATCPQSELDAETVKSILAEYKIHNADVTLRSDATADDLIDVVEGNRVYIPCIYVLNKIDQISIEELDIIYKVPHCVPISAHHRWNFDDLLEKIWDYLKLVRIYTKPKGQLPDYTSPVVLPYSRTTVEDFCMKIHKNLIKEFKYALVWGLSVKHNPQKVGKDHTLEDEDVIQIVKK", "length": 367 }, "evidence": [ { "id": "F1NX13", "url": "https://omabrowser.org/oma/group/F1NX13/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "GTPase activity", "id": "GO:0003924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003924", "evidence": [ { "database": "UniProtKB", "id": "F1NX13", "url": "https://www.uniprot.org/uniprotkb/F1NX13" } ], "pmid": "" }, { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "F1NX13", "url": "https://www.uniprot.org/uniprotkb/F1NX13" } ], "pmid": "" }, { "name": "microtubule binding", "id": "GO:0008017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008017", "evidence": [ { "database": "UniProtKB", "id": "F1NX13", "url": "https://www.uniprot.org/uniprotkb/F1NX13" } ], "pmid": "" }, { "name": "potassium ion binding", "id": "GO:0030955", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030955", "evidence": [ { "database": "UniProtKB", "id": "F1NX13", "url": "https://www.uniprot.org/uniprotkb/F1NX13" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1NX13", "url": "https://www.uniprot.org/uniprotkb/F1NX13" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F1NX13", "url": "https://www.uniprot.org/uniprotkb/F1NX13" } ], "pmid": "" }, { "name": "nuclear body", "id": "GO:0016604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016604", "evidence": [ { "database": "UniProtKB", "id": "F1NX13", "url": "https://www.uniprot.org/uniprotkb/F1NX13" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "positive regulation of microtubule polymerization", "id": "GO:0031116", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031116", "evidence": [ { "database": "UniProtKB", "id": "F1NX13", "url": "https://www.uniprot.org/uniprotkb/F1NX13" } ], "pmid": "" }, { "name": "regulation of mitotic spindle assembly", "id": "GO:1901673", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901673", "evidence": [ { "database": "UniProtKB", "id": "F1NX13", "url": "https://www.uniprot.org/uniprotkb/F1NX13" } ], "pmid": "" }, { "name": "cytoplasmic translation", "id": "GO:0002181", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002181", "evidence": [ { "database": "UniProtKB", "id": "F1NX13", "url": "https://www.uniprot.org/uniprotkb/F1NX13" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 190, "end_pos": 192, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1NX13-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 367, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1NX13-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1NX13" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 190, "end_pos": 192 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": 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"o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1NMU0-1", "uniprot_ac": "F1NMU0", "uniprot_id": "F1NMU0_CHICK", "mass": { "chemical_mass": 42838.0, "monoisotopic_mass": 42838.0 }, "refseq": { "ac": "NP_001107598", "name": "heme A synthase COX15", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001107598" }, "gene_names": [ { "name": "COX15", "type": "recommended", "evidence": [ { "id": "F1NMU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NMU0" } ] }, { "name": "COX15", "type": "synonym", "evidence": [ { "id": "NP_001107598", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001107598" } ] } ], "protein_names": [ { "name": "COX15 homolog, cytochrome c oxidase assembly protein", "type": "synonym", "evidence": [ { "id": "NP_001107598", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001107598" } ] }, { "name": "COX15, cytochrome c oxidase assembly homolog", "type": "synonym", "evidence": [ { "id": "F1NMU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NMU0/entry#names_and_taxonomy" } ] }, { "name": "cytochrome c oxidase assembly homolog 15", "type": "synonym", "evidence": [ { "id": "NP_001107598", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001107598" } ] }, { "name": "cytochrome c oxidase assembly homolog COX15", "type": "synonym", "evidence": [ { "id": "NP_001107598", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001107598" } ] }, { "name": "heme A synthase COX15", "type": "synonym", "evidence": [ { "id": "NP_001107598", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001107598" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: HAEL01003490.1, SRR13267659.205706.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: inferred from homology ##RefSeq-Attributes-END## INFERRED REFSEQ: This record is predicted by genome sequence analysis and is not yet supported by experimental evidence. The reference sequence was derived from JAENSK010000232.1. On Jan 31, 2008 this sequence version replaced XP_421700.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001107598", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001107598" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NMU0", "url": "https://www.uniprot.org/uniprotkb/F1NMU0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "COX15", "url": "https://www.uniprot.org/uniprotkb/F1NMU0", "locus": { "chromosome": "6", "start_pos": 22896237, "end_pos": 22890734, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010022234", "url": "https://www.ensembl.org/id/ENSGALG00010022234" } ] } } ], "crossref": [ { "id": "F1NMU0", "url": "https://alphafold.ebi.ac.uk/entry/F1NMU0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000007465", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000007465", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "423830", "url": "https://www.ncbi.nlm.nih.gov/gene/423830", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003780", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003780", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008389", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008389", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009003", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009003", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023754", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023754", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:423830", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423830", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "AFVCYSW", "url": "https://omabrowser.org/oma/group/AFVCYSW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZH45", "url": "https://www.orthodb.org/?gene=A0A8V0ZH45", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NMU0", "url": "https://www.orthodb.org/?gene=F1NMU0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12263", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12263", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12263:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12263:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23289", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23289", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23289:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23289:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02628", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02628", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF05493", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05493", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-189451", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-189451", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001107598", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001107598", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "63388", "url": "https://www.rhea-db.org/rhea/63388", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0ZH45", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH45", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZH45-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH45-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NMU0", "url": "https://www.uniprot.org/uniprotkb/F1NMU0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NMU0-1", "url": "https://www.uniprot.org/uniprotkb/F1NMU0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLRTLCCGGGRFFRLGPSLVPLRQPPRRGLPQQPAPAVPPAVGRWLLACSGAVAGAVVLGGVTRLTESGLSMVDWHLVKEMKPPRTQQEWEAEFQKYQQFPEFKILNHDMTLTEFKFIWYMEYSHRMWGRVVGLAYILPAAYFWRKGWLSRPMKGRVLALCGLVCFQGLLGWYMVKSGLEEKPDSHDIPRVSQYRLAAHLGSALVLYAASLWTGLSLLLPRHQLHETRQLLQLRHFAHGTTALIFLTALSGAFVAGLDAGLVYNSFPKMGERWIPDDLLAFSPTLRNIFENPTTVQFDHRILGTASVTAVTALYLFSRKISLPHRTRIAVTSLLAVAWVQVGLGISTLLLYVPTPLAATHQSGSLALLSVALWLMSELRRMPK", "length": 383, "header": "tr|F1NMU0-1|F1NMU0_CHICK Isoform 1 of COX15, cytochrome c oxidase assembly homolog OS=Gallus gallus OX=9031 GN=COX15 PE=1 SV=2 CANONICAL=F1NMU0-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZH45-1", "url": "https://www.uniprot.org/uniprotkb/F1NMU0/entry#A0A8V0ZH45-1", "sequence": { "sequence": "MGAGGPGHQHAAALRPHAVGRHAPVGFPGAAQRGPVAYERAAAHAQVTRGARLLDLPVAARTATGRGVFQLCNIKDFFGAAGVCVLAERGEGEGGQAPAIAASAAALRRPLSVRWSKRPSPPMGGGRAVSARRSLRRLAAPRGSGRDVSLSGGCGRAAAGAAMTAHSFALPLVLFSAFWGLVGIAAPWFVPKGPNRGVIITMLVTTAVCCYLFWLIAILAQANPLFGPQLKNETIWYVRFLWE", "length": 243, "header": "tr|A0A8V0ZH45-1|A0A8V0ZH45_CHICK Computationally mapped isoform of COX15, cytochrome c oxidase assembly homolog OS=Gallus gallus OX=9031 GN=COX15 PE=3 SV=1 CANONICAL=F1NMU0-1" }, "locus": { "chromosome": "6", "start_pos": 22895492, "end_pos": 22894233, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054103.1", "url": "https://www.ensembl.org/id/ENSGALT00010054103.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032634.1", "url": "https://www.ensembl.org/id/ENSGALP00010032634.1" } ] } }, { "isoform_ac": "F1NMU0-1", "url": "https://www.uniprot.org/uniprotkb/F1NMU0/entry#F1NMU0-1", "sequence": { "sequence": "MLRTLCCGGGRFFRLGPSLVPLRQPPRRGLPQQPAPAVPPAVGRWLLACSGAVAGAVVLGGVTRLTESGLSMVDWHLVKEMKPPRTQQEWEAEFQKYQQFPEFKILNHDMTLTEFKFIWYMEYSHRMWGRVVGLAYILPAAYFWRKGWLSRPMKGRVLALCGLVCFQGLLGWYMVKSGLEEKPDSHDIPRVSQYRLAAHLGSALVLYAASLWTGLSLLLPRHQLHETRQLLQLRHFAHGTTALIFLTALSGAFVAGLDAGLVYNSFPKMGERWIPDDLLAFSPTLRNIFENPTTVQFDHRILGTASVTAVTALYLFSRKISLPHRTRIAVTSLLAVAWVQVGLGISTLLLYVPTPLAATHQSGSLALLSVALWLMSELRRMPK", "length": 383, "header": "tr|F1NMU0-1|F1NMU0_CHICK Isoform 1 of COX15, cytochrome c oxidase assembly homolog OS=Gallus gallus OX=9031 GN=COX15 PE=1 SV=2 CANONICAL=F1NMU0-1" }, "locus": { "chromosome": "6", "start_pos": 22894630, "end_pos": 22890773, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054111.1", "url": "https://www.ensembl.org/id/ENSGALT00010054111.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032642.1", "url": "https://www.ensembl.org/id/ENSGALP00010032642.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:423830", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423830", "resource": "KEGG Pathway" }, { "id": "R-GGA-189451", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-189451", "resource": "Reactome", "description": "Heme biosynthesis" } ], "orthologs": [ { "uniprot_canonical_ac": "D4A414-1", "protein_name": "Cytochrome c oxidase assembly homolog COX15", "gene_name": "Cox15", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQRLFLPPLKALMGSRNVGLLVPKAASRAQCGGGSYGGRRPLRPGQYGTITEVALQSGKGTVSLPSRAAERAVGRWLLVCSGTVAGAVILGGVTRLTESGLSMVDWHLIKEMKPPTSQEEWEAEFQKYQQFPEFKILNHDMTLAEFKFIWYMEYSHRMWGRAVGLAYILPAAYFWRKGWLNRGMKGRVLALCGLVCFQGLLGWYMVKSGLEEKPESYDIPRVSQYRLAAHLGSALILYCGSLWTSLSLLLPQHKIPETRQLLWLRRFAGGTAGLVFLTALSGAFVAGLDAGLVYNSFPKMGESWIPEDLLTFSPILKNVFENPTMVQFDHRLLGVTSVTAITMLYFLSRRIPLPRRTKMAAVTLLALAYAQVALGISTLLMYVPTPLAATHQSGSLALLSGALWLMNELRRVPK", "length": 414 }, "evidence": [ { "id": "F1NMU0", "url": "https://omabrowser.org/oma/group/F1NMU0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1R355-1", "protein_name": "1.17.99.9", "gene_name": "cox15", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MMLLRLAMCRCQAARNLQQIQRTPLRQWLLQRGQNTVSSGAASVGSVSIRSAASDRLIGRWLLGCSGLVLGAVVLGGVTRLTESGLSMVDWHLVKEMKPPQTQAEWEQEFAKYQQFPEFKIMNHDMTLTEFKFIFYMEWGHRMWGRLVGLAYILPAAYFWRRGYFSRSMKTRVLGLCGFVVFQGLLGWYMVKSGLEEKPESYDVPRVSQYRLAAHLGSALLLYAASLWTGLTLLLPANRMPDSRQLLNLRRFAKMTGGLVFLTALSGAFVAGLDAGLVYNSFPKMGERWIPDDLLAFSPALKNVFENPTTVQFDHRILGIGSLTAITGLYLFSRRMILPRRAKMAISLLTAMAYTQVVLGISTLLLYVPTPLAATHQSGSVALLTFAIWVLAELRKVPK", "length": 399 }, "evidence": [ { "id": "F1NMU0", "url": "https://omabrowser.org/oma/group/F1NMU0/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1S8W1-1", "protein_name": "Cytochrome c oxidase assembly homolog COX15", "gene_name": "COX15", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MQRLLLPPLKVLMGNPCLRLLVPRAAPRTQCGCSCGIRHSLRPGQYSTITEVGLQSGRGTVSLPSKAAERVVGRWLLVCSGTVAGAVILGGVTRLTESGLSMVDWHLIKEMKPPTSQEEWEAEFQKYQQFPEFKILNHDMTLPEFKFIWYMEYSHRMWGRLVGLAYILPAAYFWRKGWLNRGLKGRVLALCGLVCFQGLLGWYMVKSGLEEKPDSHDIPRVSQYRLAAHLGSALVLYCASLWTSLSLLLPQHKLPETRQLLWLRRCAHGTAGLVFLTALSGAFVAGLDAGLVYNSFPKMGESWIPEDLFTFSPLLKNVFENPTTVQFDHRILGITSVTAITALYFLSRRIPLPRRTKIAAATLLALAYTQVGLGISTLLMYVPTPLAATHQSGSLALLSVALWLMNELRRVPK", "length": 413 }, "evidence": [ { "id": "F1NMU0", "url": "https://omabrowser.org/oma/group/F1NMU0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3IBW2-1", "protein_name": "Cytochrome c oxidase assembly protein COX15 homolog isoform X2", "gene_name": "LOC100751499", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MQRLLLPPLKAFVGSRSVGLLVPGPASRAQWGCSFGSRRPLRPGQYGTITEVALQSGKGTVPLPSKAAEQAVGRWLLVCSGTVAGAVILGGVTRLTESGLSMVDWHLIKEMKPPTSQEEWEAEFQKYQQFPEFKILNHDMTLAEFKFIWYMEYSHRMWGRAVGLAYILPAAYFWRKGWLSRGMKGRVLALCGLVCFQGLLGWYMVKSGLEEKPESYDIPRVSQYRLAAHLGSALVLYCASLWTSLSLLLPQHKLPETQQLLWLRRFAGGTAGLVFLTALSGAFVAGLDAGLVYNSFPKMGDSWIPEDLLTFSPILKNVFENPTMVQFDHRLLGITSVTAITALYFLSRRVPLPRRTKMAAVTLLALAYTQVALGISTLLMYVPTPLAATHQSGSLALLSGALWLMNELRRVPK", "length": 413 }, "evidence": [ { "id": "F1NMU0", "url": "https://omabrowser.org/oma/group/F1NMU0/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "O76740-1", "protein_name": "Cytochrome c oxidase assembly protein", "gene_name": "coxA", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MLNRAGLRCLKPSIFKQTKSNLIINNSNILSVSSRLSKNNNINQSFNNGFLQSNSKLNSIISLNNNNNNYYKRFYSNENKTNSNEQVKEEEKTNDNSSNNNEEDYKEPEQSKGNKKVGNWLLFSCGLVGAMIVIGGITRLTESGLSIVDWKPVVGAIPPITQEEWEAEFEKYKQFPEYKRLNMGMTLSEFKEIFFWEYSHRLLGRVIGVAFFFPFVWYLKKGYINRSLAKKLSVVFLMGGAQGALGWYMVKSGLDEKLIQDRGSDIPRVSQYRLAAHLGSAFVIYMALLWFGLGLVRPSALSPAMMQKLKSAMSTLAQQKSSFTIEKMKKYSHQVSGLIFLTAMSGAFVAGLDAGLVYNTFPKMGHQWIPDDIINPKIKPAYKNMFEHDVTVQFQHRVLATITYGSILALSAFAYRGRLALSPKARLATNCLLAVGTAQVALGITTLLTFVPVSLGAAHQTGSLTLLSVAIWLLHELKKLPK", "length": 482 }, "evidence": [ { "id": "F1NMU0", "url": "https://omabrowser.org/oma/group/F1NMU0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "P40086-1", "protein_name": "Heme A synthase COX15", "gene_name": "COX15", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MLFRNIEVGRQAAKLLTRTSSRLAWQSIGASRNISTIRQQIRKTQLYNFKKTVSIRPFSLSSPVFKPHVASESNPIESRLKTSKNVAYWLIGTSGLVFGIVVLGGLTRLTESGLSITEWKPVTGTLPPMNQKEWEEEFIKYKESPEFKLLNSHIDLDEFKFIFFMEWIHRLWGRAIGAVFILPAVYFAVSKKTSGHVNKRLFGLAGLLGLQGFVGWWMVKSGLDQEQLDARKSKPTVSQYRLTTHLGTAFFLYMGMLWTGLEILRECKWIKNPVQAISLFKKLDNPAIGPMRKISLALLAVSFLTAMSGGMVAGLDAGWVYNTWPKMGERWFPSSRELMDENFCRREDKKDLWWRNLLENPVTVQLVHRTCAYVAFTSVLAAHMYAIKKKAVIPRNAMTSLHVMMGVVTLQATLGILTILYLVPISLASIHQAGALALLTSSLVFASQLRKPRAPMRNVIITLPHSSKVTSGKILSEASKLASKPL", "length": 486 }, "evidence": [ { "id": "F1NMU0", "url": "https://omabrowser.org/oma/group/F1NMU0/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q08DG6-1", "protein_name": "Heme A synthase COX15", "gene_name": "COX15", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MQRLLFTPLTAFLGSPCLRLLVPRVAPRTQCGCSCGIRRPLRPGQYSTISDVALQPGRSTVSLPSKAAERVVGRWLLVCSGTVAGAVILGGVTRLTESGLSMVDWHLIKEMKPPTSKEEWEAEFQKYQQFPEFKILNHDMTLAEFKFIWYMEYSHRMWGRLVGLAYILPAAYFWKKGWLTRGLKGRVLALCGLVCFQGLLGWYMVKSGLEEKPDSHDIPRVSQYRLAAHLGSALVLYCASLWTSLSLLLPQHKLTETRQLLRLRRFAHGTAGLVFLTALSGAFVAGLDAGLVYNSFPKMGESWIPEDLFTFSPLLRNVFENPTMVQFDHRVLGIASVTAVTVLYFLSRRIPLPRRTKIAATTLLALAYTQVGLGISTLLMYVPTPLAATHQSGSLALLSVALWLMNELRRVPK", "length": 413 }, "evidence": [ { "id": "F1NMU0", "url": "https://omabrowser.org/oma/group/F1NMU0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q7KZN9-1", "protein_name": "Heme A synthase COX15", "gene_name": "COX15", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MQRLLFPPLRALKGRQYLPLLAPRAAPRAQCDCIRRPLRPGQYSTISEVALQSGRGTVSLPSKAAERVVGRWLLVCSGTVAGAVILGGVTRLTESGLSMVDWHLIKEMKPPTSQEEWEAEFQRYQQFPEFKILNHDMTLTEFKFIWYMEYSHRMWGRLVGLVYILPAAYFWRKGWLSRGMKGRVLALCGLVCFQGLLGWYMVKSGLEEKSDSHDIPRVSQYRLAAHLGSALVLYCASLWTSLSLLLPPHKLPETHQLLQLRRFAHGTAGLVFLTALSGAFVAGLDAGLVYNSFPKMGESWIPEDLFTFSPILRNVFENPTMVQFDHRILGITSVTAITVLYFLSRRIPLPRRTKMAAVTLLALAYTQVGLGISTLLMYVPTPLAATHQSGSLALLTGALWLMNELRRVPK", "length": 410 }, "evidence": [ { "id": "F1NMU0", "url": "https://omabrowser.org/oma/group/F1NMU0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8BJ03-1", "protein_name": "Heme A synthase COX15", "gene_name": "Cox15", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MQRLLLPSLRALTGSRNVGLLVPRVASRTQCGSSCGSQRPLRPGQYSTITEVALQSGKGTVSLPSRAAERAVGRWLLVCSGTVAGAVILGGVTRLTESGLSMVDWHLIKEMKPPTSQEEWEAEFQKYQQFPEFKILNHDMTLAEFKFIWYMEYSHRMWGRAVGLAYILPAAYFWRKGWLNRGMKGRVLALCGLVCFQGLLGWYMVKSGLEEKPESYDIPRVSQYRLAAHLGSALVLYCASLWTSLSLLLPQHKLPETRQLLWLRRFAGGTAGLVFLTALSGAFVAGLDAGLVYNSFPKMGESWIPEDLLTFSPVLKNVFENPTMVQFDHRLLGVTSVTAITVLYFLSRRIPLPRRTKMAAVTLLALAYAQVALGISTLLMYVPTPLAATHQSGSLALLSGALWLMNELRRVPK", "length": 413 }, "evidence": [ { "id": "F1NMU0", "url": "https://omabrowser.org/oma/group/F1NMU0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9FKT8-1", "protein_name": "Heme A synthase COX15", "gene_name": "COX15", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MFRAVGSALKRNKEAFNGIARGFTTSSHRVFTSNITAASVTSASSSPLAGNSFYGLRSLLKGQNASMFRRMSTVASISSESKEGLKLLVTGGPQAQKWVGIWLFGSAAWVFSMVVLGGVTRLTRSGLSMTDWKFTGEFPPLSDEAWAKEFEKYKQSPEYKRVNKGMNLEDFKFIYWMEYAHRMWGRGLGIMFALPFSYFLRKGYITLRLGVQLSGLFALGAGQGFIGWWMVKSGLEEPPSEYSQPRVSPYRLAAHLTSAFAIYCGLFWTALSVVMPEPPAESLAWVRGAAKVKKLALPVSLIVGITAISGAFVAGNDAGRAFNTFPKMGDTWIPDNIFEMKPLLRNFFENTATVQLDHRLLATTTLIAIGTMWWFTRKLDIHPAVKALIGSTVGMTAVQVTLGVSTLLSYVPVSLGSAHQAGALTLLTLMLLLNHTLRRPSPSLLKSLPQVAKSNFS", "length": 457 }, "evidence": [ { "id": "F1NMU0", "url": "https://omabrowser.org/oma/group/F1NMU0/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9W1F5-1", "protein_name": "Cytochrome c oxidase assembly protein COX15 homolog", "gene_name": "Dmel\\CG3803", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MLRLLQKRTNLIKLVVPGPRLHQTIAQTAIKEIPVIKPISTPKSDKTVGRWFLGVSGMVFVAVGLGGVTRLTESGLSMVTWKLTGERMPRTQEEWVQEFNLYQQYPEYKLKNVNMTVEEFKFIFMMEYMHRMWGRAIGGFFLLPAVYFWRKGYFCAKTKKSVLLLGTLIGLQGLMGWYMVKSGLEDRFQDPNDVPRVSQYRLASHLAAAFVLYSLSLSKAMSLLIPTNTFVIQAKKAFNIKGLTHLTKAMVLLTAISGAFVAGLDAGLVYNSFPKMGDKWIPDDMWTFAPIQKNITENPTTVQFNHRILGISTVTLTTALWLVTRRMQLPKRANWAINAVVAMAWTQATLGVTTLLNYVPVPLATAHQSGSLILLSFALWLSHEVRLLKYLPK", "length": 393 }, "evidence": [ { "id": "F1NMU0", "url": "https://omabrowser.org/oma/group/F1NMU0/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "proton-transporting V-type ATPase, V0 domain", "id": "GO:0033179", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033179", "evidence": [ { "database": "UniProtKB", "id": "F1NMU0", "url": "https://www.uniprot.org/uniprotkb/F1NMU0" } ], "pmid": "" }, { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "F1NMU0", "url": "https://www.uniprot.org/uniprotkb/F1NMU0" } ], "pmid": "" }, { "name": "cytochrome complex", "id": "GO:0070069", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070069", "evidence": [ { "database": "UniProtKB", "id": "F1NMU0", "url": "https://www.uniprot.org/uniprotkb/F1NMU0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "proton-transporting ATPase activity, rotational mechanism", "id": "GO:0046961", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046961", "evidence": [ { "database": "UniProtKB", "id": "F1NMU0", "url": "https://www.uniprot.org/uniprotkb/F1NMU0" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "F1NMU0", "url": "https://www.uniprot.org/uniprotkb/F1NMU0" } ], "pmid": "" }, { "name": "oxidoreductase activity, acting on the CH-CH group of donors", "id": "GO:0016627", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016627", "evidence": [ { "database": "UniProtKB", "id": "F1NMU0", "url": "https://www.uniprot.org/uniprotkb/F1NMU0" } ], "pmid": "" }, { "name": "heme A synthase activity", "id": "GO:0120547", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120547", "evidence": [ { "database": "UniProtKB", "id": "F1NMU0", "url": "https://www.uniprot.org/uniprotkb/F1NMU0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "cytochrome complex assembly", "id": "GO:0017004", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017004", "evidence": [ { "database": "UniProtKB", "id": "F1NMU0", "url": "https://www.uniprot.org/uniprotkb/F1NMU0" } ], "pmid": "" }, { "name": "heme A biosynthetic process", "id": "GO:0006784", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006784", "evidence": [ { "database": "UniProtKB", "id": "F1NMU0", "url": "https://www.uniprot.org/uniprotkb/F1NMU0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "63388", "name": "", "equation": "Fe(II)-heme o + 2 A + H2O = Fe(II)-heme a + 2 AH2", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "63388", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/63388" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1NMU0-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 383, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1NMU0-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1NMU0" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1P107-1", "uniprot_ac": "F1P107", "uniprot_id": "F1P107_CHICK", "mass": { "chemical_mass": 30310.0, "monoisotopic_mass": 30310.0 }, "refseq": { "ac": "XP_015152583", "name": "tumor protein p63-regulated gene 1-like protein isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015152583" }, "gene_names": [ { "name": "TPRG1L", "type": "recommended", "evidence": [ { "id": "F1P107", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P107" } ] }, { "name": "TPRG1L", "type": "synonym", "evidence": [ { "id": "XP_015152583", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015152583" } ] } ], "protein_names": [ { "name": "Tumor protein p63 regulated 1 like", "type": "synonym", "evidence": [ { "id": "F1P107", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P107/entry#names_and_taxonomy" } ] }, { "name": "tumor protein p63-regulated gene 1-like protein isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015152583", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015152583" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052552.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015152583", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015152583" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1P107", "url": "https://www.uniprot.org/uniprotkb/F1P107" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TPRG1L", "url": "https://www.uniprot.org/uniprotkb/F1P107", "locus": { "chromosome": "21", "start_pos": 981001, "end_pos": 984774, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021382", "url": "https://www.ensembl.org/id/ENSGALG00010021382" } ] } } ], "crossref": [ { "id": "F1P107", "url": "https://alphafold.ebi.ac.uk/entry/F1P107", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000001024", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000001024", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "419384", "url": "https://www.ncbi.nlm.nih.gov/gene/419384", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR022158", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022158", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034753", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034753", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040242", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040242", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:419384", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419384", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WNPWSSN", "url": "https://omabrowser.org/oma/group/WNPWSSN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZJD0", "url": "https://www.orthodb.org/?gene=A0A8V0ZJD0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1P107", "url": "https://www.orthodb.org/?gene=F1P107", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31108", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31108", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31108:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31108:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF12456", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12456", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015152583", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015152583", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZJD0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJD0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZJD0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJD0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1P107", "url": "https://www.uniprot.org/uniprotkb/F1P107", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1P107-1", "url": "https://www.uniprot.org/uniprotkb/F1P107-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLQLRDPEEGGPEDEEEAAGGAAALLVPGGPEPPFSAAPPRQKLRPLNVRTASRAGRLKEYFVFRPGTIEQAVSEIRAVVMPTEDGDVESVWLLTEIDHWNNEKERLVLITDRSLLICKYDFVGLQCQHVTRIALNAIDTISVGEFEFPPKSLNKREGVGIRIQWDKRSRASFINRWNPWSTNVPYATFTEHPMADADEKVASLCLLENFKTQLIQAVKKAHKEWPLPGRANGVLVLERPLLIETYVGLMSFINNEAKLGYSMTRGKIGF", "length": 270, "header": "tr|F1P107-1|F1P107_CHICK Isoform 1 of Tumor protein p63 regulated 1 like OS=Gallus gallus OX=9031 GN=TPRG1L PE=1 SV=4 CANONICAL=F1P107-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZJD0-1", "url": "https://www.uniprot.org/uniprotkb/F1P107/entry#A0A8V0ZJD0-1", "sequence": { "sequence": "MLQLRDPEEGGPEDEEEKLRPLNVRTASRAGRLKEYFVFRPGTIEQAVSEIRAVVMPTEDGDVESVWLLTEIDHWNNEKERLVLITDRSLLICKYDFVGLQCQHVTRIALNAIDTISVGEFEFPPKSLNKREGVGIRIQWDKRSRASFINRWNPWSTNVPYATFTEHPMADADEKVASLCLLENFKTQLIQAVKKAHKEWPLPGRANGVLVLERPLLIETYVGLMSFINNEAKLGYSMTRGKIGF", "length": 245, "header": "tr|A0A8V0ZJD0-1|A0A8V0ZJD0_CHICK Computationally mapped isoform of Tumor protein p63 regulated 1 like OS=Gallus gallus OX=9031 GN=TPRG1L PE=1 SV=1 CANONICAL=F1P107-1" }, "locus": { "chromosome": "21", "start_pos": 984720, "end_pos": 982542, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051801.1", "url": "https://www.ensembl.org/id/ENSGALT00010051801.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030901.1", "url": "https://www.ensembl.org/id/ENSGALP00010030901.1" } ] } }, { "isoform_ac": "F1P107-1", "url": "https://www.uniprot.org/uniprotkb/F1P107/entry#F1P107-1", "sequence": { "sequence": "MLQLRDPEEGGPEDEEEAAGGAAALLVPGGPEPPFSAAPPRQKLRPLNVRTASRAGRLKEYFVFRPGTIEQAVSEIRAVVMPTEDGDVESVWLLTEIDHWNNEKERLVLITDRSLLICKYDFVGLQCQHVTRIALNAIDTISVGEFEFPPKSLNKREGVGIRIQWDKRSRASFINRWNPWSTNVPYATFTEHPMADADEKVASLCLLENFKTQLIQAVKKAHKEWPLPGRANGVLVLERPLLIETYVGLMSFINNEAKLGYSMTRGKIGF", "length": 270, "header": "tr|F1P107-1|F1P107_CHICK Isoform 1 of Tumor protein p63 regulated 1 like OS=Gallus gallus OX=9031 GN=TPRG1L PE=1 SV=4 CANONICAL=F1P107-1" }, "locus": { "chromosome": "21", "start_pos": 984720, "end_pos": 982542, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051797.1", "url": "https://www.ensembl.org/id/ENSGALT00010051797.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030899.1", "url": "https://www.ensembl.org/id/ENSGALP00010030899.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:419384", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419384", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A5G2QRM0-1", "protein_name": "Tumor protein p63 regulated 1 like", "gene_name": "TPRG1L", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MLQLRDSVDSAGTSPTALLAAGEEVGPGGGGSGGGGGGGRPGVGTPLRQTLWPLSIHDPTRRARVKEYFVFRPGTIEQAVEEIRVVVRPVEDGDIQGVWLLTEVDHWNNEKERLVLITDQSLLICKYDFISLQCQQVVRVALSAVDTISYGEFQFPPKSLNKREGVGVRIQWDKQSRPSFISRWNPWSTSVPYTTFTEHPMAGVDEKTASLCQLEDFKALLIQAVKKAQKESPWPGQAGGVLVLERPLLIETYVGLMSFISNEAKLGYSMTRGRIGF", "length": 277 }, "evidence": [ { "id": "F1P107", "url": "https://omabrowser.org/oma/group/F1P107/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A8WCF8-1", "protein_name": "Tumor protein p63-regulated gene 1-like protein", "gene_name": "Tprg1l", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLQLRDTVDSAGTSPTAVLAAGEDAGAGRQGAGTPLRQTLWPLNVHDPTRRARVKEYFVFRPGTIEQAVEEIRAVVRPVEDGEIQGVWLLTEVDHWNNEKERLVLVTDQSLLICKYDFISLQCQQVVRVALSAVDTISCGEFQFPPKSLNKREGFGVRIQWDKQSRPSFINRWNPWSTNMPYATFIEHPMAGMDEKTASLCHLESFKALLIQAVKKAQKESPLPGQANNVLVLDRPLLIETYVGLMSFINNEAKLGYSMTRGKIGF", "length": 266 }, "evidence": [ { "id": "F1P107", "url": "https://omabrowser.org/oma/group/F1P107/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "B8A4V5-1", "protein_name": "Tumor protein p63-regulated gene 1-like protein", "gene_name": "tprg1l", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLQLNDSVITLDPESPGAAVLLSADCDDGLEVSARAGASVACCSSLQTLTPFHVHNPTMRAKVKDYFVFRPGTIEQAVNDIRTVALPSEDGEVLSVWLLAEVDHWNNEKERLVLITERSLLVCKYDFINLQCQQVIRISLNAVDTISIGEFEFPPKSLNKREGTGIRVQWDKRPRASFMNRWNPWSTDIPYATFTEHPMAHADEKVASLCQLENFKTQLIQAVKKAHKEYPIPGRANGVLILERPLLIETYLGIMSFINNEAKLGYAMTRGKIGF", "length": 275 }, "evidence": [ { "id": "F1P107", "url": "https://omabrowser.org/oma/group/F1P107/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F6QRH3-1", "protein_name": "Tumor protein p63 regulated 1 like", "gene_name": "TPRG1L", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MLQLRDSVDSAGTSPTALLAAGEEVGPGSGGGGGGGRPGVGTPLRQTLWPLSVHDPTRRARVKEYFVFRPGTIEQAVEEIRVVVRPVEDGDIQGVWLLTEVDHWNNEKERLVLITDQALLICKYDFISLQCQQVVRVALNAVDTISYGEFQFPPKSLNKREGFGIRIQWDKQSRPSFISRWNPWSTSVPYTTFIEHPMAGVDEKTASLCQLDGFKALLIQAVKKAQKESPLPGQEGGVLVLECPLLIETYVGLMSFINNEAKLGYSMTRGKIGF", "length": 274 }, "evidence": [ { "id": "F1P107", "url": "https://omabrowser.org/oma/group/F1P107/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q5T0D9-1", "protein_name": "Tumor protein p63-regulated gene 1-like protein", "gene_name": "TPRG1L", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLQLRDSVDSAGTSPTAVLAAGEEVGAGGGPGGGRPGAGTPLRQTLWPLSIHDPTRRARVKEYFVFRPGSIEQAVEEIRVVVRPVEDGEIQGVWLLTEVDHWNNEKERLVLVTEQSLLICKYDFISLQCQQVVRIALNAVDTISYGEFQFPPKSLNKREGFGIRIQWDKQSRPSFINRWNPWSTNVPYATFTEHPMAGADEKTASLCQLESFKALLIQAVKKAQKESPLPGQANGVLILERPLLIETYVGLMSFINNEAKLGYSMTRGKIGF", "length": 272 }, "evidence": [ { "id": "F1P107", "url": "https://omabrowser.org/oma/group/F1P107/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9DBS2-1", "protein_name": "Tumor protein p63-regulated gene 1-like protein", "gene_name": "Tprg1l", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLQLRDTVDSAGTSPTAVLAAGEDAGAGRPGAGTPLRQTLWPLNVHDPTRRARVKEYFVFRPGTIEQAVEEIRAVVRPVEDGEIQGVWLLTEVDHWNNEKERLVLVTDQSLLICKYDFISLQCQQVVRVALSAVDTISCGEFQFPPKSLNKREGFGVRIQWDKQSRPSFINRWNPWSTNMPYATFIEHPMAGMDEKTASLCHLESFKALLIQAVKKAQKESPLPGQANTVLVLERPLLIETYVGLMSFINNEAKLGYSMTRGKIGF", "length": 266 }, "evidence": [ { "id": "F1P107", "url": "https://omabrowser.org/oma/group/F1P107/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "calmodulin binding", "id": "GO:0005516", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005516", "evidence": [ { "database": "UniProtKB", "id": "F1P107", "url": "https://www.uniprot.org/uniprotkb/F1P107" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "F1P107", "url": "https://www.uniprot.org/uniprotkb/F1P107" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1P107", "url": "https://www.uniprot.org/uniprotkb/F1P107" } ], "pmid": "" }, { "name": "synaptic vesicle", "id": "GO:0008021", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008021", "evidence": [ { "database": "UniProtKB", "id": "F1P107", "url": "https://www.uniprot.org/uniprotkb/F1P107" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1P107-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 270, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1P107-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1P107" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1NHD1-1", "uniprot_ac": "F1NHD1", "uniprot_id": "F1NHD1_CHICK", "mass": { "chemical_mass": 75434.0, "monoisotopic_mass": 75434.0 }, "refseq": { "ac": "NP_001383742", "name": "double-stranded RNA-binding protein Staufen homolog 1 isoform 4", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001383742" }, "gene_names": [ { "name": "STAU1", "type": "recommended", "evidence": [ { "id": "F1NHD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NHD1" } ] }, { "name": "STAU1", "type": "synonym", "evidence": [ { "id": "NP_001383742", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001383742" } ] }, { "name": "STAU", "type": "synonym", "evidence": [ { "id": "NP_001383742", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001383742" } ] } ], "protein_names": [ { "name": "Double-stranded RNA-binding protein Staufen homolog 1", "type": "recommended", "evidence": [ { "id": "F1NHD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NHD1/entry#names_and_taxonomy" } ] }, { "name": "double-stranded RNA-binding protein Staufen homolog 1 isoform 4", "type": "synonym", "evidence": [ { "id": "NP_001383742", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001383742" } ] }, { "name": "double-stranded RNA-binding protein Staufen homolog 1", "type": "synonym", "evidence": [ { "id": "NP_001383742", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001383742" } ] }, { "name": "staufen, RNA binding protein, homolog 1", "type": "synonym", "evidence": [ { "id": "NP_001383742", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001383742" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: SRR13267659.19907.1, SRR13267655.225223.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000328.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001383742", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001383742" } ] }, { "annotation": "Binds double-stranded RNA (regardless of the sequence) and tubulin. May play a role in specific positioning of mRNAs at given sites in the cell by cross-linking cytoskeletal and RNA components, and in stimulating their translation at the site.", "evidence": [ { "database": "UniProtKB", "id": "F1NHD1", "url": "https://www.uniprot.org/uniprotkb/F1NHD1#function" }, { "database": "UniProtKB", "id": "ARBA00057371", "url": "https://www.uniprot.org/uniprotkb/ARBA00057371#function" }, { "database": "UniProtKB", "id": "A0A8V0ZQ69", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ69#function" }, { "database": "UniProtKB", "id": "A0A8V0ZXG7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXG7#function" }, { "database": "UniProtKB", "id": "A0A8V0ZXH3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXH3#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NHD1", "url": "https://www.uniprot.org/uniprotkb/F1NHD1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "STAU1", "url": "https://www.uniprot.org/uniprotkb/F1NHD1", "locus": { "chromosome": "20", "start_pos": 6803926, "end_pos": 6774106, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010024030", "url": "https://www.ensembl.org/id/ENSGALG00010024030" } ] } } ], "crossref": [ { "id": "F1NHD1", "url": "https://alphafold.ebi.ac.uk/entry/F1NHD1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000004736", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000004736", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd19879", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd19879", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd19881", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd19881", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd19883", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd19883", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd19885", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd19885", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd19887", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd19887", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "419213", "url": "https://www.ncbi.nlm.nih.gov/gene/419213", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR014720", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014720", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032478", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032478", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044475", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044475", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051740", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051740", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZQ69", "url": "https://www.orthodb.org/?gene=A0A8V0ZQ69", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZXG7", "url": "https://www.orthodb.org/?gene=A0A8V0ZXG7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZXH3", "url": "https://www.orthodb.org/?gene=A0A8V0ZXH3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NHD1", "url": "https://www.orthodb.org/?gene=F1NHD1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46054", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46054", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46054:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46054:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00035", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00035", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16482", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16482", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001383742", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001383742", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZQ69", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ69", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZQ69-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ69-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZXG7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXG7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZXG7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXG7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZXH3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXH3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZXH3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXH3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NHD1", "url": "https://www.uniprot.org/uniprotkb/F1NHD1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NHD1-1", "url": "https://www.uniprot.org/uniprotkb/F1NHD1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSQVQIQNPSTALAGSQILNKNPSLSQPLSIPSTTSSLPSENAGRPIQNSALPSASVTSTNAAAAPSNMANPKEKTPMCLVNELARFNKIQPEYKLLSEQGPAHSKVFTVQLTLGDQHWEAEGTSIKKAQHAAAAKALEGTKFPKPTARPSRSEGKNPDSVTPTVELNALCMKLGKKPMYKPIDPYTGMRSTYNYTMRGGTYPPRYFYPFPVGPLLYQVELSIGGQQFHGKGRTRQAAKHDAAAKALKVLQNEPLPEKPEVNGKEPDDENLNKSEISQVFEIALKRNLPVNFEVTKESGPPHMKSFVTKVSVGEFMGEGEGKSKKISKKNAAIAVLEELKKLPPLPTVEKMKPRIKKKTKSIVKLQTSPEYGQGMNPISRLAQIQQAKKEKEPEYMLITERGLPRRREFVMQVKVGVHTAEGMGTNKKVAKRNAAENMLEILGFKIPQPQPPKPALKTEEKTPVKKPGDGRKVTFFEPGSEETSTSNKEDEFRMPYLSHQQLPAGILPMVPEVAQAVGASQGHHTKEFNRAAPNPAKATVTAMIARELLYGGTSPTAETILKNNNSSGHVPHGPLTRPSEQLDYLSNVQGIQVEYKDFPKNNKNEFVSLINCSSQPPLISHGIGKDVESCHDMAALNILKLLSELDQQTTEMPRTGNGPMSVCVKQEMESDPLLKPANSNTLGQTLDSTA", "length": 690, "header": "tr|F1NHD1-1|F1NHD1_CHICK Isoform 1 of Double-stranded RNA-binding protein Staufen homolog 1 OS=Gallus gallus OX=9031 GN=STAU1 PE=1 SV=3 CANONICAL=F1NHD1-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZQ69-1", "url": "https://www.uniprot.org/uniprotkb/F1NHD1/entry#A0A8V0ZQ69-1", "sequence": { "sequence": "MSQVQIQNPSTALAGSQILNKNPSLSQPLSIPSTTSSLPSENAGRPIQNSALPSASVTSTNAAAAPSNMANPKEKTPMCLVNELARFNKIQPEYKLLSEQGPAHSKVFTVQLTLGDQHWEAEGTSIKKAQHAAAAKALEGTKFPKPTARPSRSEGKNPDSVTPTVELNALCMKLGKKPMYKPIDPYTGMRSTYNYTMRGGTYPPRYFYPFPVGPLLYQVELSIGGQQFHGKGRTRQAAKHDAAAKALKVLQNEPLPEKPEVNGKEPDDENLNKSEISQVFEIALKRNLPVNFEVTKESGPPHMKSFVTKVSVGEFMGEGEGKSKKISKKNAAIAVLEELKKLPPLPTVEKMKPRIKKKTKSIVKLQTSPEYGQGMNPISRLAQIQQAKKEKEPEYMLITERGLPRRREFVMQVKVGVHTAEGMGTNKKVAKRNAAENMLEILGFKIPQPQPPKPALKTEEKTPVKKPGDGRKVTFFEPGSEETSTSNKEDEFRMPYLSHQQLPAGILPMVPEVAQAVGASQGHHTKEFNRAAPNPAKATVTAMIARELLYGGTSPTAETILKNNNSSGHVPHGPLTRPSEQLDYLSNVQGIQVEYKDFPKNNKNEFVSLINCSSQPPLISHGIGKDVESCHDMAALNILKLLSELDQQTTEMPRTGNGPMSV", "length": 662, "header": "tr|A0A8V0ZQ69-1|A0A8V0ZQ69_CHICK Computationally mapped isoform of Double-stranded RNA-binding protein Staufen homolog 1 OS=Gallus gallus OX=9031 GN=STAU1 PE=1 SV=1 CANONICAL=F1NHD1-1" }, "locus": { "chromosome": "20", "start_pos": 6800795, "end_pos": 6784226, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010058525.1", "url": "https://www.ensembl.org/id/ENSGALT00010058525.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010035572.1", "url": "https://www.ensembl.org/id/ENSGALP00010035572.1" } ] } }, { "isoform_ac": "A0A8V0ZXG7-1", "url": "https://www.uniprot.org/uniprotkb/F1NHD1/entry#A0A8V0ZXG7-1", "sequence": { "sequence": "MSQVQIQNPSTALAGSQILNKNPSLSQPLSIPSTTSSLPSENAGRPIQNSALPSASVTSTNAAAAPSNMANPKEKTPMCLVNELARFNKIQPEYKLLSEQGPAHSKVFTVQLTLGDQHWEAEGTSIKKAQHAAAAKALEGTKFPKPTARPSRSEGKNPDSVTPTVELNALCMKLGKKPMYKPIDPYTGMRSTYNYTMRGGTYPPRYFYPFPVGPLLYQVELSIGGQQFHGKGRTRQAAKHDAAAKALKVLQNEPLPEKPEVTKESGPPHMKSFVTKVSVGEFMGEGEGKSKKISKKNAAIAVLEELKKLPPLPTVEKMKPRIKKKTKSIVKLQTSPEYGQGMNPISRLAQIQQAKKEKEPEYMLITERGLPRRREFVMQVKVGVHTAEGMGTNKKVAKRNAAENMLEILGFKIPQPQPPKPALKTEEKTPVKKPGDGRKVTFFEPGSEETSTSNKEDEFRMPYLSHQQLPAGILPMVPEVAQAVGASQGHHTKEFNRAAPNPAKATVTAMIARELLYGGTSPTAETILKNNNSSGHVPHGPLTRPSEQLDYLSNVQGIQVEYKDFPKNNKNEFVSLINCSSQPPLISHGIGKDVESCHDMAALNILKLLSELDQQTTEMPRTGNGPMSVGVKIPRAVTFLRRTRGCVKQEMESDPLLKPANSNTLGQTLDSTA", "length": 673, "header": "tr|A0A8V0ZXG7-1|A0A8V0ZXG7_CHICK Computationally mapped isoform of Double-stranded RNA-binding protein Staufen homolog 1 OS=Gallus gallus OX=9031 GN=STAU1 PE=1 SV=1 CANONICAL=F1NHD1-1" }, "locus": { "chromosome": "20", "start_pos": 6801521, "end_pos": 6784226, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010058532.1", "url": "https://www.ensembl.org/id/ENSGALT00010058532.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010035576.1", "url": "https://www.ensembl.org/id/ENSGALP00010035576.1" } ] } }, { "isoform_ac": "A0A8V0ZXH3-1", "url": "https://www.uniprot.org/uniprotkb/F1NHD1/entry#A0A8V0ZXH3-1", "sequence": { "sequence": "MSQVQIQNPSTALAGSQILNKNPSLSQPLSIPSTTSSLPSENAGRPIQNSALPSASVTSTNAAAAPSNMANPKEKTPMCLVNELARFNKIQPEYKLLSEQGPAHSKVFTVQLTLGDQHWEAEGTSIKKAQHAAAAKALEGTKFPKPTARPSRSEGKNPDSVTPTVELNALCMKLGKKPMYKPIDPYTGMRSTYNYTMRGGTYPPRYFYPFPVGPLLYQVELSIGGQQFHGKGRTRQAAKHDAAAKALKVLQNEPLPEKPEVTKESGPPHMKSFVTKVSVGEFMGEGEGKSKKISKKNAAIAVLEELKKLPPLPTVEKMKPRIKKKTKSIVKLQTSPEYGQGMNPISRLAQIQQAKKEKEPEYMLITERGLPRRREFVMQVKVGVHTAEGMGTNKKVAKRNAAENMLEILGFKIPQPQPPKPALKTEEKTPVKKPGDGRKVTFFEPGSEETSTSNKEDEFRMPYLSHQQLPAGILPMVPEVAQAVGASQGHHTKEFNRAAPNPAKATVTAMIARELLYGGTSPTAETILKNNNSSGHVPHGPLTRPSEQLDYLSNVQGIQVEYKDFPKNNKNEFVSLINCSSQPPLISHGIGKDVESCHDMAALNILKLLSELDQQTTEMPRTGNGPMSVCVKQEMESDPLLKPANSNTLGQTLDSTA", "length": 657, "header": "tr|A0A8V0ZXH3-1|A0A8V0ZXH3_CHICK Computationally mapped isoform of Double-stranded RNA-binding protein Staufen homolog 1 OS=Gallus gallus OX=9031 GN=STAU1 PE=1 SV=1 CANONICAL=F1NHD1-1" }, "locus": { "chromosome": "20", "start_pos": 6801521, "end_pos": 6784226, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010058538.1", "url": "https://www.ensembl.org/id/ENSGALT00010058538.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010035581.1", "url": "https://www.ensembl.org/id/ENSGALP00010035581.1" } ] } }, { "isoform_ac": "F1NHD1-1", "url": "https://www.uniprot.org/uniprotkb/F1NHD1/entry#F1NHD1-1", "sequence": { "sequence": "MSQVQIQNPSTALAGSQILNKNPSLSQPLSIPSTTSSLPSENAGRPIQNSALPSASVTSTNAAAAPSNMANPKEKTPMCLVNELARFNKIQPEYKLLSEQGPAHSKVFTVQLTLGDQHWEAEGTSIKKAQHAAAAKALEGTKFPKPTARPSRSEGKNPDSVTPTVELNALCMKLGKKPMYKPIDPYTGMRSTYNYTMRGGTYPPRYFYPFPVGPLLYQVELSIGGQQFHGKGRTRQAAKHDAAAKALKVLQNEPLPEKPEVNGKEPDDENLNKSEISQVFEIALKRNLPVNFEVTKESGPPHMKSFVTKVSVGEFMGEGEGKSKKISKKNAAIAVLEELKKLPPLPTVEKMKPRIKKKTKSIVKLQTSPEYGQGMNPISRLAQIQQAKKEKEPEYMLITERGLPRRREFVMQVKVGVHTAEGMGTNKKVAKRNAAENMLEILGFKIPQPQPPKPALKTEEKTPVKKPGDGRKVTFFEPGSEETSTSNKEDEFRMPYLSHQQLPAGILPMVPEVAQAVGASQGHHTKEFNRAAPNPAKATVTAMIARELLYGGTSPTAETILKNNNSSGHVPHGPLTRPSEQLDYLSNVQGIQVEYKDFPKNNKNEFVSLINCSSQPPLISHGIGKDVESCHDMAALNILKLLSELDQQTTEMPRTGNGPMSVCVKQEMESDPLLKPANSNTLGQTLDSTA", "length": 690, "header": "tr|F1NHD1-1|F1NHD1_CHICK Isoform 1 of Double-stranded RNA-binding protein Staufen homolog 1 OS=Gallus gallus OX=9031 GN=STAU1 PE=1 SV=3 CANONICAL=F1NHD1-1" }, "locus": { "chromosome": "20", "start_pos": 6801521, "end_pos": 6784226, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010058540.1", "url": "https://www.ensembl.org/id/ENSGALT00010058540.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010035583.1", "url": "https://www.ensembl.org/id/ENSGALP00010035583.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "F1NHD1", "url": "https://www.uniprot.org/uniprotkb/F1NHD1" } ], "pmid": "" }, { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "F1NHD1", "url": "https://www.uniprot.org/uniprotkb/F1NHD1" } ], "pmid": "" }, { "name": "double-stranded RNA binding", "id": "GO:0003725", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003725", "evidence": [ { "database": "UniProtKB", "id": "F1NHD1", "url": "https://www.uniprot.org/uniprotkb/F1NHD1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 9, "go_terms": [ { "name": "rough endoplasmic reticulum", "id": "GO:0005791", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005791", "evidence": [ { "database": "UniProtKB", "id": "F1NHD1", "url": "https://www.uniprot.org/uniprotkb/F1NHD1" } ], "pmid": "" }, { "name": "neuron projection", "id": "GO:0043005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043005", "evidence": [ { "database": "UniProtKB", "id": "F1NHD1", "url": "https://www.uniprot.org/uniprotkb/F1NHD1" } ], "pmid": "" }, { "name": "cytoplasmic ribonucleoprotein granule", "id": "GO:0036464", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036464", "evidence": [ { "database": "UniProtKB", "id": "F1NHD1", "url": "https://www.uniprot.org/uniprotkb/F1NHD1" } ], "pmid": "" }, { "name": "protein-containing complex", "id": "GO:0032991", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032991", "evidence": [ { "database": "UniProtKB", "id": "F1NHD1", "url": "https://www.uniprot.org/uniprotkb/F1NHD1" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F1NHD1", "url": "https://www.uniprot.org/uniprotkb/F1NHD1" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F1NHD1", "url": "https://www.uniprot.org/uniprotkb/F1NHD1" } ], "pmid": "" }, { "name": "neuronal cell body", "id": "GO:0043025", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043025", "evidence": [ { "database": "UniProtKB", "id": "F1NHD1", "url": "https://www.uniprot.org/uniprotkb/F1NHD1" } ], "pmid": "" }, { "name": "dendrite cytoplasm", "id": "GO:0032839", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032839", "evidence": [ { "database": "UniProtKB", "id": "F1NHD1", "url": "https://www.uniprot.org/uniprotkb/F1NHD1" } ], "pmid": "" }, { "name": "cytoplasmic stress granule", "id": "GO:0010494", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010494", "evidence": [ { "database": "UniProtKB", "id": "F1NHD1", "url": "https://www.uniprot.org/uniprotkb/F1NHD1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "positive regulation by virus of viral protein levels in host cell", "id": "GO:0046726", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046726", "evidence": [ { "database": "UniProtKB", "id": "F1NHD1", "url": "https://www.uniprot.org/uniprotkb/F1NHD1" } ], "pmid": "" }, { "name": "germ cell development", "id": "GO:0007281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007281", "evidence": [ { "database": "UniProtKB", "id": "F1NHD1", "url": "https://www.uniprot.org/uniprotkb/F1NHD1" } ], "pmid": "" }, { "name": "protein localization to synapse", "id": "GO:0035418", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035418", "evidence": [ { "database": "UniProtKB", "id": "F1NHD1", "url": "https://www.uniprot.org/uniprotkb/F1NHD1" } ], "pmid": "" }, { "name": "positive regulation of viral genome replication", "id": "GO:0045070", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045070", "evidence": [ { "database": "UniProtKB", "id": "F1NHD1", "url": "https://www.uniprot.org/uniprotkb/F1NHD1" } ], "pmid": "" }, { "name": "intracellular mRNA localization", "id": "GO:0008298", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008298", "evidence": [ { "database": "UniProtKB", "id": "F1NHD1", "url": "https://www.uniprot.org/uniprotkb/F1NHD1" } ], "pmid": "" }, { "name": "anterograde dendritic transport of messenger ribonucleoprotein complex", "id": "GO:0098964", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098964", "evidence": [ { "database": "UniProtKB", "id": "F1NHD1", "url": "https://www.uniprot.org/uniprotkb/F1NHD1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 194, "end_pos": 196, "annotation": "n_glycosylation_sequon" }, { "start_pos": 272, "end_pos": 274, "annotation": "n_glycosylation_sequon" }, { "start_pos": 564, "end_pos": 566, "annotation": "n_glycosylation_sequon" }, { "start_pos": 565, "end_pos": 567, "annotation": "n_glycosylation_sequon" }, { "start_pos": 611, "end_pos": 613, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1NHD1-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 690, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1NHD1-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1NHD1" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1NHD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NHD1" }, { "id": "PS50137", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50137" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "DRBM", "eco_id": "ECO_0000259", "start_pos": 76, "end_pos": 143, "start_aa": "Thr", "end_aa": "Phe", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 194, "end_pos": 196 }, { "start_pos": 272, "end_pos": 274 }, { "start_pos": 564, "end_pos": 566 }, { "start_pos": 565, "end_pos": 567 }, { "start_pos": 611, "end_pos": 613 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1NW13-1", "uniprot_ac": "F1NW13", "uniprot_id": "F1NW13_CHICK", "mass": { "chemical_mass": 44124.0, "monoisotopic_mass": 44124.0 }, "refseq": { "ac": "XP_417402", "name": "calcium-responsive transactivator", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_417402" }, "gene_names": [ { "name": "SS18L1", "type": "recommended", "evidence": [ { "id": "F1NW13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NW13" } ] }, { "name": "SS18L1", "type": "synonym", "evidence": [ { "id": "XP_417402", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_417402" } ] } ], "protein_names": [ { "name": "SS18L1 subunit of BAF chromatin remodeling complex", "type": "synonym", "evidence": [ { "id": "F1NW13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NW13/entry#names_and_taxonomy" } ] }, { "name": "calcium-responsive transactivator", "type": "synonym", "evidence": [ { "id": "XP_417402", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_417402" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052551.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 19, 2013 this sequence version replaced XP_417402.3. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_417402", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_417402" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NW13", "url": "https://www.uniprot.org/uniprotkb/F1NW13" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SS18L1", "url": "https://www.uniprot.org/uniprotkb/F1NW13", "locus": { "chromosome": "20", "start_pos": 8099339, "end_pos": 8084335, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010022825", "url": "https://www.ensembl.org/id/ENSGALG00010022825" } ] } } ], "crossref": [ { "id": "F1NW13", "url": "https://alphafold.ebi.ac.uk/entry/F1NW13", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000005145", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000005145", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "419225", "url": "https://www.ncbi.nlm.nih.gov/gene/419225", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR007726", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007726", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:419225", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419225", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "ASEPMNQ", "url": "https://omabrowser.org/oma/group/ASEPMNQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZQ88", "url": "https://www.orthodb.org/?gene=A0A8V0ZQ88", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NW13", "url": "https://www.orthodb.org/?gene=F1NW13", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23107", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23107", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23107:SF21", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23107:SF21", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05030", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05030", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-9933937", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9933937", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9933947", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9933947", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_417402", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_417402", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZQ88", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ88", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZQ88-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ88-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NW13", "url": "https://www.uniprot.org/uniprotkb/F1NW13", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NW13-1", "url": "https://www.uniprot.org/uniprotkb/F1NW13-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSVAFASARPRGKGEVTQQTIQKMLDENHHLIQCIMDYQSKGKTAECTQYQQILHRNLVYLATIADSNQNMQSLLPAPPTQNINLGPGGMTQSASNQSLHSQSNLSDAIGTGLPPSSLMQSQISNGPNHVPMQQSGQNTMPTTSLSMTVSSHGTGPGYSHTVPASQNVPMQGQGSIGNYVSRTNINMQSNPVSMMHQQAATSHYNSAQGGSQHYQGQSSIAMMSQSNQGNSMMGQRPMGPYRASQQGSSQQYMGQEEYYSEQYSHGQGSSEPMNQQYYPDGHGDYAYQQSSYTEQSYDRSFDDSTQHYYEGGNSQYSQQQAGYQQGAAQQQTYSQQQYPNQQSYPGQQQGYGPAQGASSQYSSYQQGQGQQYGSYRASQTGPSAQQQRPYGYEQGQYGNYQQ", "length": 402, "header": "tr|F1NW13-1|F1NW13_CHICK Isoform 1 of SS18L1 subunit of BAF chromatin remodeling complex OS=Gallus gallus OX=9031 GN=SS18L1 PE=3 SV=2 CANONICAL=F1NW13-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZQ88-1", "url": "https://www.uniprot.org/uniprotkb/F1NW13/entry#A0A8V0ZQ88-1", "sequence": { "sequence": "MRAPANPPSLPQKMLDENHHLIQCIMDYQSKGKTAECTQYQQILHRNLVYLATIADSNQNMQSLLPAPPTQNINLGPGGMTQSASNQSLHSQSNLSDAIGTGLPPSSLMQSQISNGPNHVPMQQSGQNTMPTTSLSMTVSSHGTGPGYSHTVPASQNVPMQGQGSIGNYVSRTNINMQSNPVSMMHQQAATSHYNSAQGGSQHYQGQSSIAMMSQSNQGNSMMGQRPMGPYRASQQGSSQQYMGQEEYYSEQYSHGQGSSEPMNQQYYPDGHGDYAYQQSSYTEQSYDRSFDDSTQHYYEGGNSQYSQQQAGYQQGAAQQQTYSQQQYPNQQSYPGQQQGYGPAQGASSQYSSYQQGQGQQYGSYRASQTGPSAQQQRPYGYEQGQYGNYQQ", "length": 392, "header": "tr|A0A8V0ZQ88-1|A0A8V0ZQ88_CHICK Computationally mapped isoform of SS18L1 subunit of BAF chromatin remodeling complex OS=Gallus gallus OX=9031 GN=SS18L1 PE=3 SV=1 CANONICAL=F1NW13-1" }, "locus": { "chromosome": "20", "start_pos": 8097160, "end_pos": 8085047, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010055517.1", "url": "https://www.ensembl.org/id/ENSGALT00010055517.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033631.1", "url": "https://www.ensembl.org/id/ENSGALP00010033631.1" } ] } }, { "isoform_ac": "F1NW13-1", "url": "https://www.uniprot.org/uniprotkb/F1NW13/entry#F1NW13-1", "sequence": { "sequence": "MSVAFASARPRGKGEVTQQTIQKMLDENHHLIQCIMDYQSKGKTAECTQYQQILHRNLVYLATIADSNQNMQSLLPAPPTQNINLGPGGMTQSASNQSLHSQSNLSDAIGTGLPPSSLMQSQISNGPNHVPMQQSGQNTMPTTSLSMTVSSHGTGPGYSHTVPASQNVPMQGQGSIGNYVSRTNINMQSNPVSMMHQQAATSHYNSAQGGSQHYQGQSSIAMMSQSNQGNSMMGQRPMGPYRASQQGSSQQYMGQEEYYSEQYSHGQGSSEPMNQQYYPDGHGDYAYQQSSYTEQSYDRSFDDSTQHYYEGGNSQYSQQQAGYQQGAAQQQTYSQQQYPNQQSYPGQQQGYGPAQGASSQYSSYQQGQGQQYGSYRASQTGPSAQQQRPYGYEQGQYGNYQQ", "length": 402, "header": "tr|F1NW13-1|F1NW13_CHICK Isoform 1 of SS18L1 subunit of BAF chromatin remodeling complex OS=Gallus gallus OX=9031 GN=SS18L1 PE=3 SV=2 CANONICAL=F1NW13-1" }, "locus": { "chromosome": "20", "start_pos": 8097160, "end_pos": 8084391, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010055523.1", "url": "https://www.ensembl.org/id/ENSGALT00010055523.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033638.1", "url": "https://www.ensembl.org/id/ENSGALP00010033638.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:419225", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419225", "resource": "KEGG Pathway" }, { "id": "R-GGA-9933937", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9933937", "resource": "Reactome", "description": "Formation of the canonical BAF (cBAF) complex" }, { "id": "R-GGA-9933947", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9933947", "resource": "Reactome", "description": "Formation of the non-canonical BAF (ncBAF) complex" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287B0J9-1", "protein_name": "SS18L1 subunit of BAF chromatin remodeling complex", "gene_name": "SS18L1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSVAFASARPRGKGEVTQQTIQKMLDENHHLIQCILDYQSKGKTAECTQYQQILHRNLVYLATIADSNQNMQSLLPAPPTQSMTLGPGGLSQSGSSQGLHAQGSLGDAIGAGLPPSSLMQAQIGNGPNHVSLQQTAPSTLPTTSMSMSGSSHGSGPGYSHSGPASQSVPLQGQGTISNYVSRANINMQSNPVSMMHQQAASSHYSAAQGGAQHYQGQSMAMMGQSGQGSGMIGQRPMAPYRPSQQGSSQQYLGQEEYYGGEQYGHSQAASEPLSQQYYPDGHGDYAYQPSSYTEQSYDRSFEESTQHYYEGGNSQYSQQQAGYQQGTAQQQTYSQQQYPNQQGYPGQQQGYGPAQGAPSQYPSYQQGQGQQYGSYRASQTGPSAQQQRPYGYEQGQYGNYQQ", "length": 402 }, "evidence": [ { "id": "F1NW13", "url": "https://omabrowser.org/oma/group/F1NW13/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "O75177-1", "protein_name": "Calcium-responsive transactivator", "gene_name": "SS18L1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSVAFASARPRGKGEVTQQTIQKMLDENHHLIQCILEYQSKGKTAECTQYQQILHRNLVYLATIADSNQNMQSLLPAPPTQNMNLGPGALTQSGSSQGLHSQGSLSDAISTGLPPSSLLQGQIGNGPSHVSMQQTAPNTLPTTSMSISGPGYSHAGPASQGVPMQGQGTIGNYVSRTNINMQSNPVSMMQQQAATSHYSSAQGGSQHYQGQSSIAMMGQGSQGSSMMGQRPMAPYRPSQQGSSQQYLGQEEYYGEQYSHSQGAAEPMGQQYYPDGHGDYAYQQSSYTEQSYDRSFEESTQHYYEGGNSQYSQQQAGYQQGAAQQQTYSQQQYPSQQSYPGQQQGYGSAQGAPSQYPGYQQGQGQQYGSYRAPQTAPSAQQQRPYGYEQGQYGNYQQ", "length": 396 }, "evidence": [ { "id": "F1NW13", "url": "https://omabrowser.org/oma/group/F1NW13/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q08E31-1", "protein_name": "Calcium-responsive transactivator", "gene_name": "SS18L1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSVAFASARPRGKGEVTQQTIQKMLDENHHLIQCILDYQSKGKTAECTQYQQILHRNLVYLATIADSNQNMQSLLPAPPTQSMTLGPGGLSQSGSAQGLHSQGSLSDAIGAGLPPSSLMQAQIGNGPNHVSLQQTAQSTLPTTSMSMSGSGHGSGPGYSHSGPASQSVPLQSQGAISNYVSRANINMQSNPVSMMHQQAASSHYSAAQGGSQHYQGQSMAMMGQSGQGGGVMGQRPMAPYRPSQQGSSQQYLGQEEYYGGEQYGHGQAASEPMSQQYYPDGHGDYAYQPASYTDQSYDRSFEDSTQHYYEGGNSQYSQQQTGYQQGTAQQQTYSQQQYPNQQSYPGQQQGYGPAQGAPSQYSSYQQGQGQQYGSYRASQTGPSTQQQRPYGYEQGQYGNYQQ", "length": 402 }, "evidence": [ { "id": "F1NW13", "url": "https://omabrowser.org/oma/group/F1NW13/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q8BW22-1", "protein_name": "Calcium-responsive transactivator", "gene_name": "Ss18l1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSVAFASARPRGKGEVTQQTIQKMLDENHHLIQCILDYQSKGKTAECTQYQQILHRNLVYLATIADSNQNMQSLLPAPPTQNMNLGPGALSQSGSSQGLHPQGSLSDTVSTGLPPASLMQGQIGNGPNHVSMQQTAQSTLPTTSMSLSGSGHGTGPGYSHSGPTSQSVPMQGQGAISNYVSRTNINMQSNPVSMMHQQAATSHYNSAQGGSQHYQGQAPIAMMGQGGQGGSMMGQRPMAPYRPSQQGSSQQYLGQEEYYSEQYSHSQGSAEPMSQQYYPDGHGDYAYQQSSYTEQSYDRSFEDPTQHYYEGGNSQYSQQQAGYQQGTAQQQTYSQQQYPNQQSYPGQQQGYGPAQGAPSQYSSYQQGQGQQYGSYRTSQTGPSAQQQRPYGYEQGQYGNYQQ", "length": 402 }, "evidence": [ { "id": "F1NW13", "url": "https://omabrowser.org/oma/group/F1NW13/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q91XJ0-1", "protein_name": "Calcium-responsive transcription coactivator", "gene_name": "Ss18l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSVAFASARPRGKGEVTQQTIQKMLDENHHLIQCILDYQSKGKTAECTQYQQILHRNLVYLATIADSNQNMQSLLPAPPTQNMNLGPGALSQSGSSQGLHPQGSLSDTVSTGLPPASLMQGQIGNGPNHVSMQQTAQSTLPTTSMSMSGSGHGTGPGYSHSGPTSQSVPMQGQGAISNYVSRTNINMQSNPVSMMHQQAARPTTTQRRVEASITRARRPLHDGPGWQGGSMMGQRPMAPYRPSQQGSSQQYLGQEEYYSEQYSHSQGSAEPMSQQYYPDGHSDYAYQQSSYTEQSYDRSFEDPTQHYYEGGNSQYSQQQAGYQQGTAQQQTYSQQQYPNQQSYPGQQQGYGPAQGAPSQYSGYQQGQGQQYGSYRTSQTGPSAQQQRPYGYEQGQYGNYQQ", "length": 401 }, "evidence": [ { "id": "F1NW13", "url": "https://omabrowser.org/oma/group/F1NW13/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "F1NW13", "url": "https://www.uniprot.org/uniprotkb/F1NW13" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1NW13", "url": "https://www.uniprot.org/uniprotkb/F1NW13" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F1NW13", "url": "https://www.uniprot.org/uniprotkb/F1NW13" } ], "pmid": "" }, { "name": "nBAF complex", "id": "GO:0071565", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071565", "evidence": [ { "database": "UniProtKB", "id": "F1NW13", "url": "https://www.uniprot.org/uniprotkb/F1NW13" } ], "pmid": "" }, { "name": "kinetochore", "id": "GO:0000776", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000776", "evidence": [ { "database": "UniProtKB", "id": "F1NW13", "url": "https://www.uniprot.org/uniprotkb/F1NW13" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "F1NW13", "url": "https://www.uniprot.org/uniprotkb/F1NW13" } ], "pmid": "" }, { "name": "chromatin organization", "id": "GO:0006325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006325", "evidence": [ { "database": "UniProtKB", "id": "F1NW13", "url": "https://www.uniprot.org/uniprotkb/F1NW13" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "F1NW13", "url": "https://www.uniprot.org/uniprotkb/F1NW13" } ], "pmid": "" }, { "name": "positive regulation of dendrite morphogenesis", "id": "GO:0050775", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050775", "evidence": [ { "database": "UniProtKB", "id": "F1NW13", "url": "https://www.uniprot.org/uniprotkb/F1NW13" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "transcription coactivator activity", "id": "GO:0003713", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003713", "evidence": [ { "database": "UniProtKB", "id": "F1NW13", "url": "https://www.uniprot.org/uniprotkb/F1NW13" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 104, "end_pos": 106, "annotation": "n_glycosylation_sequon" }, { "start_pos": 96, "end_pos": 98, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1NW13-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 402, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1NW13-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1NW13" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1NW13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NW13" }, { "id": "PF05030", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05030" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SS18 N-terminal", "eco_id": "ECO_0000259", "start_pos": 13, "end_pos": 73, "start_aa": "Lys", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 104, "end_pos": 106 }, { "start_pos": 96, "end_pos": 98 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1NZ33-1", "uniprot_ac": "F1NZ33", "uniprot_id": "F1NZ33_CHICK", "mass": { "chemical_mass": 32967.0, "monoisotopic_mass": 32967.0 }, "refseq": { "ac": "NP_001006499", "name": "tetraspanin-15", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006499" }, "gene_names": [ { "name": "TSPAN15", "type": "recommended", "evidence": [ { "id": "F1NZ33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NZ33" } ] }, { "name": "TSPAN15", "type": "synonym", "evidence": [ { "id": "NP_001006499", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006499" } ] }, { "name": "tetraspanin-15", "type": "synonym", "evidence": [ { "id": "NP_001006499", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006499" } ] } ], "protein_names": [ { "name": "Tetraspanin", "type": "recommended", "evidence": [ { "id": "F1NZ33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NZ33/entry#names_and_taxonomy" } ] }, { "name": "tetraspanin-15", "type": "synonym", "evidence": [ { "id": "NP_001006499", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006499" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ720604.1, HAEK01019378.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000229.1. On Sep 23, 2021 this sequence version replaced NP_001006499.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001006499", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006499" } ] }, { "annotation": "Part of TspanC8 subgroup, composed of 6 members that interact with the transmembrane metalloprotease ADAM10. This interaction is required for ADAM10 exit from the endoplasmic reticulum and for enzymatic maturation and trafficking to the cell surface as well as substrate specificity. Different TspanC8/ADAM10 complexes have distinct substrates. Promotes ADAM10-mediated cleavage of CDH2. Negatively regulates ligand-induced Notch activity probably by regulating ADAM10 activity.", "evidence": [ { "database": "UniProtKB", "id": "F1NZ33", "url": "https://www.uniprot.org/uniprotkb/F1NZ33#function" }, { "database": "UniProtKB", "id": "ARBA00056423", "url": "https://www.uniprot.org/uniprotkb/ARBA00056423#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NZ33", "url": "https://www.uniprot.org/uniprotkb/F1NZ33" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TSPAN15", "url": "https://www.uniprot.org/uniprotkb/F1NZ33", "locus": { "chromosome": "6", "start_pos": 11684518, "end_pos": 11672941, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010023259", "url": "https://www.ensembl.org/id/ENSGALG00010023259" } ] } } ], "crossref": [ { "id": "F1NZ33", "url": "https://alphafold.ebi.ac.uk/entry/F1NZ33", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000004257", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000004257", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd03158", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03158", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "423699", "url": "https://www.ncbi.nlm.nih.gov/gene/423699", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000301", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000301", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008952", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008952", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018499", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018499", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:423699", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423699", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "FAGAGCC", "url": "https://omabrowser.org/oma/group/FAGAGCC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZVJ5", "url": "https://www.orthodb.org/?gene=A0A8V0ZVJ5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NZ33", "url": "https://www.orthodb.org/?gene=F1NZ33", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR19282", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19282", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19282:SF159", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19282:SF159", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00335", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00335", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001006499", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006499", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZVJ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVJ5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZVJ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVJ5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NZ33", "url": "https://www.uniprot.org/uniprotkb/F1NZ33", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NZ33-1", "url": "https://www.uniprot.org/uniprotkb/F1NZ33-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MATGDAEQARYCARLSYLCLKFSLITYCTAFWVIGGLVLAVGIYAEVERQKYKTLESAFLAPAIILILLGIIMFFVSFVGVLASLRDNLCLLQAFMYILGLCLMIELAGAVVALIFRNQTIKFLNDNIRRGIENYYDDLDFKNIMDSVQKRFKCCGGEDYTDWSKNAYHDCAAPGPLACGVPYTCCVRNKTDIINTMCGYKTIDQERLSIQDVIYIRGCTNAVLIWFLDNYSIMAGVLLGILLPQFLGVLLSLLYITRVEDIIAEHKLGESLFGGTRQHPDPEFASPGCCMCYPG", "length": 295, "header": "tr|F1NZ33-1|F1NZ33_CHICK Isoform 1 of Tetraspanin OS=Gallus gallus OX=9031 GN=TSPAN15 PE=1 SV=2 CANONICAL=F1NZ33-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZVJ5-1", "url": "https://www.uniprot.org/uniprotkb/F1NZ33/entry#A0A8V0ZVJ5-1", "sequence": { "sequence": "MATGDAEQARYCARLSYLCLKFSLITYCTAFWVIGGLVLAVGIYAEVERQKYKTLESAFLAPAIILILLGIIMFFVSFVGVLASLRDNLCLLQAVSTVCFFFIIVLAYCLVASALKTALFQLFSPAVRRVSVTICHLPFSFVSCLQFKCCGGEDYTDWSKNAYHDCAAPGPLACGVPYTCCVRNKLFNNVCSVALQRLSIQDVIYIRGCTNAVLIWFLDNYSIMAGVLLGILLPQFLGVLLSLLYITRVEDIIAEHKLGESLFGGTRQHPDPEFASPGCCMCYPG", "length": 285, "header": "tr|A0A8V0ZVJ5-1|A0A8V0ZVJ5_CHICK Computationally mapped isoform of Tetraspanin 15 OS=Gallus gallus OX=9031 GN=TSPAN15 PE=3 SV=1 CANONICAL=F1NZ33-1" }, "locus": { "chromosome": "6", "start_pos": 11683522, "end_pos": 11673008, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056717.1", "url": "https://www.ensembl.org/id/ENSGALT00010056717.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034459.1", "url": "https://www.ensembl.org/id/ENSGALP00010034459.1" } ] } }, { "isoform_ac": "F1NZ33-1", "url": "https://www.uniprot.org/uniprotkb/F1NZ33/entry#F1NZ33-1", "sequence": { "sequence": "MATGDAEQARYCARLSYLCLKFSLITYCTAFWVIGGLVLAVGIYAEVERQKYKTLESAFLAPAIILILLGIIMFFVSFVGVLASLRDNLCLLQAFMYILGLCLMIELAGAVVALIFRNQTIKFLNDNIRRGIENYYDDLDFKNIMDSVQKRFKCCGGEDYTDWSKNAYHDCAAPGPLACGVPYTCCVRNKTDIINTMCGYKTIDQERLSIQDVIYIRGCTNAVLIWFLDNYSIMAGVLLGILLPQFLGVLLSLLYITRVEDIIAEHKLGESLFGGTRQHPDPEFASPGCCMCYPG", "length": 295, "header": "tr|F1NZ33-1|F1NZ33_CHICK Isoform 1 of Tetraspanin OS=Gallus gallus OX=9031 GN=TSPAN15 PE=1 SV=2 CANONICAL=F1NZ33-1" }, "locus": { "chromosome": "6", "start_pos": 11683522, "end_pos": 11673008, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056712.1", "url": "https://www.ensembl.org/id/ENSGALT00010056712.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034454.1", "url": "https://www.ensembl.org/id/ENSGALP00010034454.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:423699", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423699", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "F7BWT7-1", "protein_name": "Tetraspanin-15", "gene_name": "Tspan15", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPRGDSEQVRYCARFSYLWLKFSLIIYSTVFWLIGGLVLSVGIYAEAERQKYKTLESAFLAPAIILILLGVVMFIVSFIGVLASLRDNLCLLQSFMYILGICLVMELIGGIVALIFRNQTIDFLNDNIRRGIENYYDDLDFKNIMDFVQKKFKCCGGEDYRDWSKNQYHDCSAPGPLACGVPYTCCIRNTTDVVNTMCGYKTIDKERLNAQNIIHVRGCTNAVLIWFMDNYTIMAGLLLGILLPQFLGVLLTLLYITRVEDIILEHSVTDGLLGPGAKSRTDTAGTGCCLCYPD", "length": 294 }, "evidence": [ { "id": "F1NZ33", "url": "https://omabrowser.org/oma/group/F1NZ33/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "O95858-1", "protein_name": "Tetraspanin-15", "gene_name": "TSPAN15", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPRGDSEQVRYCARFSYLWLKFSLIIYSTVFWLIGALVLSVGIYAEVERQKYKTLESAFLAPAIILILLGVVMFMVSFIGVLASLRDNLYLLQAFMYILGICLIMELIGGVVALTFRNQTIDFLNDNIRRGIENYYDDLDFKNIMDFVQKKFKCCGGEDYRDWSKNQYHDCSAPGPLACGVPYTCCIRNTTEVVNTMCGYKTIDKERFSVQDVIYVRGCTNAVIIWFMDNYTIMAGILLGILLPQFLGVLLTLLYITRVEDIIMEHSVTDGLLGPGAKPSVEAAGTGCCLCYPN", "length": 294 }, "evidence": [ { "id": "F1NZ33", "url": "https://omabrowser.org/oma/group/F1NZ33/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q1JQA4-1", "protein_name": "Tetraspanin-15", "gene_name": "TSPAN15", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MPRGDSEQVRYCARFSYLWLKFSLVIYSTVFWLIGGLVLSVGIYAEVERQKYKTLESAFLAPAIILILLGVVMFIVSFIGVLASLRDNLCLLQAFMYILGICLIIELIGGVVALIFRNQTIDFLNDNIRRGIENYYDDLDFKNIMDFVQKEFKCCGGEDYRDWSKNQYHDCRAPGPLACGVPYTCCFRNTTEVVNTMCGYKTIDKERLSVQNVIYVRGCTNAVLMWFTDNYTIMAGVLLGILLPQFLGVLLTFLYITRVEDIITEHSVTDGLLGPGTKAGVEAAGTGCCMCYPI", "length": 294 }, "evidence": [ { "id": "F1NZ33", "url": "https://omabrowser.org/oma/group/F1NZ33/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "F1NZ33", "url": "https://www.uniprot.org/uniprotkb/F1NZ33" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F1NZ33", "url": "https://www.uniprot.org/uniprotkb/F1NZ33" } ], "pmid": "" }, { "name": "cell surface", "id": "GO:0009986", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009986", "evidence": [ { "database": "UniProtKB", "id": "F1NZ33", "url": "https://www.uniprot.org/uniprotkb/F1NZ33" } ], "pmid": "" }, { "name": "tetraspanin-enriched microdomain", "id": "GO:0097197", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097197", "evidence": [ { "database": "UniProtKB", "id": "F1NZ33", "url": "https://www.uniprot.org/uniprotkb/F1NZ33" } ], "pmid": "" }, { "name": "late endosome membrane", "id": "GO:0031902", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031902", "evidence": [ { "database": "UniProtKB", "id": "F1NZ33", "url": "https://www.uniprot.org/uniprotkb/F1NZ33" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "enzyme binding", "id": "GO:0019899", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019899", "evidence": [ { "database": "UniProtKB", "id": "F1NZ33", "url": "https://www.uniprot.org/uniprotkb/F1NZ33" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "protein localization to plasma membrane", "id": "GO:0072659", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072659", "evidence": [ { "database": "UniProtKB", "id": "F1NZ33", "url": "https://www.uniprot.org/uniprotkb/F1NZ33" } ], "pmid": "" }, { "name": "protein maturation", "id": "GO:0051604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051604", "evidence": [ { "database": "UniProtKB", "id": "F1NZ33", "url": "https://www.uniprot.org/uniprotkb/F1NZ33" } ], "pmid": "" }, { "name": "negative regulation of Notch signaling pathway", "id": "GO:0045746", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045746", "evidence": [ { "database": "UniProtKB", "id": "F1NZ33", "url": "https://www.uniprot.org/uniprotkb/F1NZ33" } ], "pmid": "" }, { "name": "regulation of membrane protein ectodomain proteolysis", "id": "GO:0051043", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051043", "evidence": [ { "database": "UniProtKB", "id": "F1NZ33", "url": "https://www.uniprot.org/uniprotkb/F1NZ33" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 118, "end_pos": 120, "annotation": "n_glycosylation_sequon" }, { "start_pos": 189, "end_pos": 191, "annotation": "n_glycosylation_sequon" }, { "start_pos": 230, "end_pos": 232, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1NZ33-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 295, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1NZ33-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1NZ33" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 118, "end_pos": 120 }, { "start_pos": 189, "end_pos": 191 }, { "start_pos": 230, "end_pos": 232 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 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"field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1NJK8-1", "uniprot_ac": "F1NJK8", "uniprot_id": "F1NJK8_CHICK", "mass": { "chemical_mass": 45253.0, "monoisotopic_mass": 45253.0 }, "refseq": { "ac": "XP_423669", "name": "protein arginine N-methyltransferase 8 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_423669" }, "gene_names": [ { "name": "PRMT1", "type": "recommended", "evidence": [ { "id": "F1NJK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NJK8" } ] }, { "name": "PRMT1", "type": "synonym", "evidence": [ { "id": "XP_423669", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_423669" } ] } ], "protein_names": [ { "name": "type I protein arginine methyltransferase", "type": "recommended", "evidence": [ { "id": "F1NJK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NJK8/entry#names_and_taxonomy" } ] }, { "name": "2.1.1.319", "type": "synonym", "evidence": [ { "id": "F1NJK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NJK8/entry#names_and_taxonomy" } ] }, { "name": "protein arginine N-methyltransferase 8 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_423669", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_423669" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Dec 16, 2011 this sequence version replaced XP_423669.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_423669", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_423669" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NJK8", "url": "https://www.uniprot.org/uniprotkb/F1NJK8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PRMT1", "url": "https://www.uniprot.org/uniprotkb/F1NJK8", "locus": {} } ], "crossref": [ { "id": "F1NJK8", "url": "https://alphafold.ebi.ac.uk/entry/F1NJK8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000013272", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000013272", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd02440", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02440", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "425989", "url": "https://www.ncbi.nlm.nih.gov/gene/425989", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR025799", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025799", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029063", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029063", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055135", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055135", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "CTHTKVK", "url": "https://omabrowser.org/oma/group/CTHTKVK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A2W3", "url": "https://www.orthodb.org/?gene=A0A8V1A2W3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A676", "url": "https://www.orthodb.org/?gene=A0A8V1A676", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NJK8", "url": "https://www.orthodb.org/?gene=F1NJK8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11006", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11006", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11006:SF47", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11006:SF47", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF06325", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06325", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF22528", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22528", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_423669", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_423669", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "48096", "url": "https://www.rhea-db.org/rhea/48096", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "48100", "url": "https://www.rhea-db.org/rhea/48100", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V1A2W3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2W3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A2W3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2W3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A676", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A676", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A676-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A676-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NJK8", "url": "https://www.uniprot.org/uniprotkb/F1NJK8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NJK8-1", "url": "https://www.uniprot.org/uniprotkb/F1NJK8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGMKHSSRCLLLRRKMAENGAESTEVCPVPSQTPQPTVVPKPVQSVIHVPLQPGCPGRGKMAKFLSPEEMTSRDYYFDSYAHFGIHEEMLKDEVRTLTYRNSMYHNKHVFKDKIVLDVGSGTGILSMFAAKAGAKKVYGIECSSISDYSEKIIKANHLDNIITIFKGKVEEVELPVDKVDIIISEWMGYCLFYESMLNTVIFARDKWLKPGGLMFPDRAALYVVAIEDRQYKDFKIHWWENVYGFDMTCIRDVAMKEPLVDIVDPKQVVTNACLIKEVDIYTVKTEELAFTSAFCLQIQRNDYIHALVTYFNIEFTKCHKKMGFSTAPDAPYTHWKQTVFYLEDYLTVRRGEEIYGTISMKPNAKNVRDLDFTIDLDFKGQLCEASVSNDYKMR", "length": 394, "header": "tr|F1NJK8-1|F1NJK8_CHICK Isoform 1 of type I protein arginine methyltransferase OS=Gallus gallus OX=9031 GN=PRMT1 PE=4 SV=3 CANONICAL=F1NJK8-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A2W3-1", "url": "https://www.uniprot.org/uniprotkb/F1NJK8/entry#A0A8V1A2W3-1", "sequence": { "sequence": "MLIRACKMAKFLSPEEMTSRDYYFDSYAHFGIHEEMLKDEVRTLTYRNSMYHNKHVFKDKIVLDVGSGTGILSMFAAKAGAKKVYGIECSSISDYSEKIIKANHLDNIITIFKGKVEEVELPVDKVDIIISEWMGYCLFYESMLNTVIFARDKWLKPGGLMFPDRAALYVVAIEDRQYKDFKIHWWENVYGFDMTCIRDVAMKEPLVDIVDPKQVVTNACLIKEVDIYTVKTEELAFTSAFCLQIQRNDYIHALVTYFNIEFTKCHKKMGFSTAPDAPYTHWKQTVFYLEDYLTVRRGEEIYGTISMKPNAKNVRDLDFTIDLDFKGQLCEASVSNDYKMR", "length": 341, "header": "tr|A0A8V1A2W3-1|A0A8V1A2W3_CHICK Computationally mapped isoform of type I protein arginine methyltransferase OS=Gallus gallus OX=9031 GN=PRMT1 PE=4 SV=1 CANONICAL=F1NJK8-1" }, "locus": { "chromosome": "1", "start_pos": 75230902, "end_pos": 75205533, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010060081.1", "url": "https://www.ensembl.org/id/ENSGALT00010060081.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010036841.1", "url": "https://www.ensembl.org/id/ENSGALP00010036841.1" } ] } }, { "isoform_ac": "A0A8V1A676-1", "url": "https://www.uniprot.org/uniprotkb/F1NJK8/entry#A0A8V1A676-1", "sequence": { "sequence": "MGMKHSSRCLLLRRKMAENGAESTEVCPVPSQTPQPTVVPKPVQSVIHVPLQPGCPGRGKMAKFLSPEEMTSRDYYFDSYAHFGIHEEMLKDEVRTLTYRNSMYHNKHVFKDKIVLDVGSGTGILSMFAAKAGAKKVYGIECSSISDYSEKIIKANHLDNIITIFKGKVEEVELPVDKVDIIISEWMGYCLFYESMLNTVIFARDKWLKPGGLMFPDRAALYVVAIEDRQYKDFKIHWWENVYGFDMTCIRDVAMKEPLVDIVDPKQVVTNACLIKEVDIYTVKTEELAFTSAFCLQIQRNDYIHALVTYFNIEFTKCHKKMGFSTGNLYFCSISISSCLSVLLVRWYMRVYRNKKFSFQ", "length": 360, "header": "tr|A0A8V1A676-1|A0A8V1A676_CHICK Computationally mapped isoform of type I protein arginine methyltransferase OS=Gallus gallus OX=9031 GN=PRMT1 PE=4 SV=1 CANONICAL=F1NJK8-1" }, "locus": { "chromosome": "1", "start_pos": 75226557, "end_pos": 75180648, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010060084.1", "url": "https://www.ensembl.org/id/ENSGALT00010060084.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010036844.1", "url": "https://www.ensembl.org/id/ENSGALP00010036844.1" } ] } }, { "isoform_ac": "F1NJK8-1", "url": "https://www.uniprot.org/uniprotkb/F1NJK8/entry#F1NJK8-1", "sequence": { "sequence": "MGMKHSSRCLLLRRKMAENGAESTEVCPVPSQTPQPTVVPKPVQSVIHVPLQPGCPGRGKMAKFLSPEEMTSRDYYFDSYAHFGIHEEMLKDEVRTLTYRNSMYHNKHVFKDKIVLDVGSGTGILSMFAAKAGAKKVYGIECSSISDYSEKIIKANHLDNIITIFKGKVEEVELPVDKVDIIISEWMGYCLFYESMLNTVIFARDKWLKPGGLMFPDRAALYVVAIEDRQYKDFKIHWWENVYGFDMTCIRDVAMKEPLVDIVDPKQVVTNACLIKEVDIYTVKTEELAFTSAFCLQIQRNDYIHALVTYFNIEFTKCHKKMGFSTAPDAPYTHWKQTVFYLEDYLTVRRGEEIYGTISMKPNAKNVRDLDFTIDLDFKGQLCEASVSNDYKMR", "length": 394, "header": "tr|F1NJK8-1|F1NJK8_CHICK Isoform 1 of type I protein arginine methyltransferase OS=Gallus gallus OX=9031 GN=PRMT1 PE=4 SV=3 CANONICAL=F1NJK8-1" }, "locus": { "chromosome": "1", "start_pos": 75230902, "end_pos": 75180648, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010060087.1", "url": "https://www.ensembl.org/id/ENSGALT00010060087.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010036847.1", "url": "https://www.ensembl.org/id/ENSGALP00010036847.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 37, "start_aa": "Thr", "end_pos": 37, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr37", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A5G2QGR4-1", "protein_name": "type I protein arginine methyltransferase", "gene_name": "PRMT8", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGMKHSSRCLLLRRKMAENAAENTEVSSPPIQPPQPVVPAKPVQCVHHVSTQPSCPGRGKMSKLLNPEEMTSRDYYFDSYAHFGIHEEMLKDEVRTLTYRNSMYHNKHVFKDKVVLDVGSGTGILSMFAAKAGAKKVFGIECSSISDYSEKIIKANHLDNIITIFKGKVEEVELPVEKVDIIISEWMGYCLFYESMLNTVIFARDKWLKPGGLMFPDRAALYVVAIEDRQYKDFKIHWWENVYGFDMTCIRDVAMKEPLVDIVDPKQVVTNACLIKEVDIYTVKTEELSFTSAFCLQIQRNDYVHALVTYFNIEFTKCHKKMGFSTAPDAPYTHWKQTVFYLEDYLTVRRGEEIYGTISMKPNAKNVRDLDFTVDLDFKGQLCETSVSNYYKMR", "length": 394 }, "evidence": [ { "id": "F1NJK8", "url": "https://omabrowser.org/oma/group/F1NJK8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8C2LPN7-1", "protein_name": "type I protein arginine methyltransferase", "gene_name": "Prmt8", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MGMKHSSRCLLLRRKMAENAVESTEVSSAPPQPPQPVVPAKPVQCVHHVSTQPSCPGRGKMSKLLNPEEMTSRDYYFDSYAHFGIHEEMLKDEVRTLTYRNSMYHNKHVFKDKVVLDVGSGTGILSMFAAKAGAKKVFGIECSSISDYSEKIIKANHLDNVITIFKGKVEEVELPVDKVDIIISEWMGYCLFYESMLNTVIFARDKWLKPGGLMFPDRAALYVVAIEDRQYKDFKIHWWENVYGFDMTCIRDVAMKEPLVDIVDPKQVVTNACLIKEVDIYTVKTEELSFTSAFCLQIQRNDYVHALVTYFNIEFTKCHKKMGFSTAPDAPYTHWKQTVFYLEDYLTVRRGEEIYGTISMKPNAKNVRDLDFTVDLDFKGQLCETSVSNDYKMR", "length": 394 }, "evidence": [ { "id": "F1NJK8", "url": "https://omabrowser.org/oma/group/F1NJK8/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0ABK0M8P3-1", "protein_name": "type I protein arginine methyltransferase", "gene_name": "Prmt8", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGMKHSSRCLLLRRKMAENAVESTEVSSAPPQPPQPVIPAKPVQCVHHVSTQPSCPGRGKMSKLLNPEEMTSRDYYFDSYAHFGIHEEMLKDEVRTLTYRNSMYHNKHVFKDKVVLDVGSGTGILSMFAAKAGAKKVFGIECSSISDYSEKIIKANHLDNVITIFKGKVEEVELPVEKVDIIISEWMGYCLFYESMLNTVIFARDKWLKPGGLMFPDRAALYVVAIEDRQYKDFKIHWWENVYGFDMTCIRDVAMKEPLVDIVDPKQVVTNACLIKEVDIYTVKTEELSFTSAFCLQIQRNDYVHALVTYFNIEFTKCHKKMGFSTAPDAPYTHWKQTVFYLEDYLTVRRGEEIYGTISMKPNAKNVRDLDFTVDLDFKGQLCETSVSNDYKMR", "length": 394 }, "evidence": [ { "id": "F1NJK8", "url": "https://omabrowser.org/oma/group/F1NJK8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1MEB9-1", "protein_name": "type I protein arginine methyltransferase", "gene_name": "PRMT8", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGMKHSSRCLLLRRKMAENAAESTEVSSPPSQPPQPVVPAKPVQCVHHVSTQPSCPGRGKMSKLLNPEEMTSRDYYFDSYAHFGIHEEMLKDEVRTLTYRNSMYHNKHVFKDKVVLDVGSGTGILSMFAAKAGAKKVFGIECSSISDYSEKIIKANHLDNIITIFKGKVEEVELPVEKVDIIISEWMGYCLFYESMLATVIFARDKWLKPGGLMFPDRAALYVVAIEDRQYKDFKIHWWENVYGFDMTCIRDVAMKEPLVDIVDPKQVVTNACLIKEVDIYTVKTEELSFTSAFCLQVQRNDYVHALVTYFNIEFTKCHKKMGFSTAPDAPYTHWKQTVFYLEDYLTVRRGEEIYGTISMKPNAKNVRDLDFTVDLDFKGQLCETSVSNYYKMR", "length": 394 }, "evidence": [ { "id": "F1NJK8", "url": "https://omabrowser.org/oma/group/F1NJK8/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P38074-1", "protein_name": "Protein arginine N-methyltransferase 1", "gene_name": "HMT1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSKTAVKDSATEKTKLSESEQHYFNSYDHYGIHEEMLQDTVRTLSYRNAIIQNKDLFKDKIVLDVGCGTGILSMFAAKHGAKHVIGVDMSSIIEMAKELVELNGFSDKITLLRGKLEDVHLPFPKVDIIISEWMGYFLLYESMMDTVLYARDHYLVEGGLIFPDKCSIHLAGLEDSQYKDEKLNYWQDVYGFDYSPFVPLVLHEPIVDTVERNNVNTTSDKLIEFDLNTVKISDLAFKSNFKLTAKRQDMINGIVTWFDIVFPAPKGKRPVEFSTGPHAPYTHWKQTIFYFPDDLDAETGDTIEGELVCSPNEKNNRDLNIKISYKFESNGIDGNSRSRKNEGSYLMH", "length": 348 }, "evidence": [ { "id": "F1NJK8", "url": "https://omabrowser.org/oma/group/F1NJK8/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q54EF2-1", "protein_name": "Protein arginine N-methyltransferase 1", "gene_name": "prmt1", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MTETNKNVDALEKINQMSSADYYFDSYSHFGIHEEMLKDEVRTLAYRRAIINNRKLFEGKVVLDVGCGTGILCMFAAQAGAKMVIGVDNSEMLPIAQKIITANNFDKTITLIKGKMEEVVLPVDKVDIIISEWMGYFMLYEGMLDTVLYARDKYLVPGGVILPDKASLYITAIEDQDYKEEKINYWNNVYGFDMSCIREIALKEPLVDVVQPNMIVTNDCCILTVDIMTITKDELKFRSDFKLKALRDDLIHAFVVYFDIEFSKGDKPVCFSTGPKAKYTHWKQSIMYFEDHIKIQQGEIITGTMDCAPFDKNQRDLKIKLDFNFAGELMKSSSSLEYHMR", "length": 341 }, "evidence": [ { "id": "F1NJK8", "url": "https://omabrowser.org/oma/group/F1NJK8/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q6PAK3-1", "protein_name": "Protein arginine N-methyltransferase 8", "gene_name": "Prmt8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGMKHSSRCLLLRRKMAENAVESTEVSSAPPQPPQPVIPAKPVQCVHHVSTQPSCPGRGKMSKLLNPEEMTSRDYYFDSYAHFGIHEEMLKDEVRTLTYRNSMYHNKHVFKDKVVLDVGSGTGILSMFAAKAGAKKVFGIECSSISDYSEKIIKANHLDNVITIFKGKVEEVELPVEKVDIIISEWMGYCLFYESMLNTVIFARDKWLKPGGLMFPDRAALYVVAIEDRQYKDFKIHWWENVYGFDMTCIRDVAMKEPLVDIVDPKQVVTNACLIKEVDIYTVKTEELSFTSAFCLQIQRNDYVHALVTYFNIEFTKCHKKMGFSTAPDAPYTHWKQTVFYLEDYLTVRRGEEIYGTISMKPNAKNVRDLDFTVDLDFKGQLCETSVSNDYKMR", "length": 394 }, "evidence": [ { "id": "F1NJK8", "url": "https://omabrowser.org/oma/group/F1NJK8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9NR22-1", "protein_name": "Protein arginine N-methyltransferase 8", "gene_name": "PRMT8", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGMKHSSRCLLLRRKMAENAAESTEVNSPPSQPPQPVVPAKPVQCVHHVSTQPSCPGRGKMSKLLNPEEMTSRDYYFDSYAHFGIHEEMLKDEVRTLTYRNSMYHNKHVFKDKVVLDVGSGTGILSMFAAKAGAKKVFGIECSSISDYSEKIIKANHLDNIITIFKGKVEEVELPVEKVDIIISEWMGYCLFYESMLNTVIFARDKWLKPGGLMFPDRAALYVVAIEDRQYKDFKIHWWENVYGFDMTCIRDVAMKEPLVDIVDPKQVVTNACLIKEVDIYTVKTEELSFTSAFCLQIQRNDYVHALVTYFNIEFTKCHKKMGFSTAPDAPYTHWKQTVFYLEDYLTVRRGEEIYGTISMKPNAKNVRDLDFTVDLDFKGQLCETSVSNDYKMR", "length": 394 }, "evidence": [ { "id": "F1NJK8", "url": "https://omabrowser.org/oma/group/F1NJK8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9SU94-1", "protein_name": "Protein arginine N-methyltransferase 1.1", "gene_name": "PRMT11", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MTKNSNHDENEFISFEPNQNTKIRFEDADEDEVAEGSGVAGEETPQDESMFDAGESADTAEVTDDTTSADYYFDSYSHFGIHEEMLKDVVRTKTYQNVIYQNKFLIKDKIVLDVGAGTGILSLFCAKAGAAHVYAVECSQMADMAKEIVKANGFSDVITVLKGKIEEIELPTPKVDVIISEWMGYFLLFENMLDSVLYARDKWLVEGGVVLPDKASLHLTAIEDSEYKEDKIEFWNSVYGFDMSCIKKKAMMEPLVDTVDQNQIVTDSRLLKTMDISKMSSGDASFTAPFKLVAQRNDYIHALVAYFDVSFTMCHKLLGFSTGPKSRATHWKQTVLYLEDVLTICEGETITGTMSVSPNKKNPRDIDIKLSYSLNGQHCKISRTQHYKMR", "length": 390 }, "evidence": [ { "id": "F1NJK8", "url": "https://omabrowser.org/oma/group/F1NJK8/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9VGW7-1", "protein_name": "type I protein arginine methyltransferase", "gene_name": "Art1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MASTDIPMEAAVESATGITPNSNANSNNVAKKLPAEGSTGDNPNANADEMTSRDYYFDSYAHFGIHEEMLKDEVRTVTYRNAMYHNKHLFQGKTVLDVGCGTGILSMFAAKAGAAQVIAVDCSNIIEFARQVVIDNNLQDVITVVKGKIEEIELPNGIEGVDIIISEWMGYCLFYESMLDTVLYARDKWLKKDGMMFPDRGTLYITAIEDRQYKDEKINWWDDVYGFDMSCIRKVAVTEPLVDVVDPKQVVSTSCMVKEVDLYTVQKADLNFSSKFSLCIKRNDFVQALVTYFNIEFTKCHKRLGFSTSPDSTYTHWKQTVFYLDDHMTAKKNEEITGTFQMKPNERNNRDLDFVIDINFKGELSQIQESNTYRMR", "length": 376 }, "evidence": [ { "id": "F1NJK8", "url": "https://omabrowser.org/oma/group/F1NJK8/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 7, "go_terms": [ { "name": "protein-arginine omega-N asymmetric methyltransferase activity", "id": "GO:0035242", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035242", "evidence": [ { "database": "UniProtKB", "id": "F1NJK8", "url": "https://www.uniprot.org/uniprotkb/F1NJK8" } ], "pmid": "" }, { "name": "enzyme binding", "id": "GO:0019899", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019899", "evidence": [ { "database": "UniProtKB", "id": "F1NJK8", "url": "https://www.uniprot.org/uniprotkb/F1NJK8" } ], "pmid": "" }, { "name": "protein homodimerization activity", "id": "GO:0042803", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042803", "evidence": [ { "database": "UniProtKB", "id": "F1NJK8", "url": "https://www.uniprot.org/uniprotkb/F1NJK8" } ], "pmid": "" }, { "name": "histone methyltransferase activity", "id": "GO:0042054", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042054", "evidence": [ { "database": "UniProtKB", "id": "F1NJK8", "url": "https://www.uniprot.org/uniprotkb/F1NJK8" } ], "pmid": "" }, { "name": "protein-arginine omega-N monomethyltransferase activity", "id": "GO:0035241", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035241", "evidence": [ { "database": "UniProtKB", "id": "F1NJK8", "url": "https://www.uniprot.org/uniprotkb/F1NJK8" } ], "pmid": "" }, { "name": "S-adenosyl-L-methionine binding", "id": "GO:1904047", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904047", "evidence": [ { "database": "UniProtKB", "id": "F1NJK8", "url": "https://www.uniprot.org/uniprotkb/F1NJK8" } ], "pmid": "" }, { "name": "histone H4 methyltransferase activity", "id": "GO:0140939", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140939", "evidence": [ { "database": "UniProtKB", "id": "F1NJK8", "url": "https://www.uniprot.org/uniprotkb/F1NJK8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "methylation", "id": "GO:0032259", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032259", "evidence": [ { "database": "UniProtKB", "id": "F1NJK8", "url": "https://www.uniprot.org/uniprotkb/F1NJK8" } ], "pmid": "" }, { "name": "chromatin remodeling", "id": "GO:0006338", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006338", "evidence": [ { "database": "UniProtKB", "id": "F1NJK8", "url": "https://www.uniprot.org/uniprotkb/F1NJK8" } ], "pmid": "" }, { "name": "protein homooligomerization", "id": "GO:0051260", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051260", "evidence": [ { "database": "UniProtKB", "id": "F1NJK8", "url": "https://www.uniprot.org/uniprotkb/F1NJK8" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "F1NJK8", "url": "https://www.uniprot.org/uniprotkb/F1NJK8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F1NJK8", "url": "https://www.uniprot.org/uniprotkb/F1NJK8" } ], "pmid": "" }, { "name": "cytoplasmic side of plasma membrane", "id": "GO:0009898", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009898", "evidence": [ { "database": "UniProtKB", "id": "F1NJK8", "url": "https://www.uniprot.org/uniprotkb/F1NJK8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "48096", "name": "", "equation": "L-arginyl-[protein] + 2 S-adenosyl-L-methionine = N(omega),N(omega)-dimethyl-L-arginyl-[protein] + 2 S-adenosyl-L-homocysteine + 2 H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0ZDB7-1", "F1NJK8-1" ], "evidence": [ { "id": "48096", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/48096" } ] }, { "id": "48100", "name": "", "equation": "L-arginyl-[protein] + S-adenosyl-L-methionine = N(omega)-methyl-L-arginyl-[protein] + S-adenosyl-L-homocysteine + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q5ZIB9-1", "A0A8V0ZYF3-1", "A0A8V0ZDB7-1", "F1NJK8-1" ], "evidence": [ { "id": "48100", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/48100" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A8V0ZDB7", "gene_name": "PRMT3", "activity": [ { "ec_number": "2.1.1.319", "activity": "L-arginyl-[protein] + 2 S-adenosyl-L-methionine = N(omega),N(omega)-dimethyl-L-arginyl-[protein] + 2 S-adenosyl-L-homocysteine + 2 H(+).", "evidence": [ { "id": "A0A8V0ZDB7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDB7" } ] }, { "ec_number": "2.1.1.319", "activity": "", "evidence": [ { "id": "A0A8V0ZDB7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDB7" } ] } ] }, { "uniprot_ac": "A0A8V0ZYF3", "gene_name": "PRMT7", "activity": [ { "ec_number": "2.1.1.321", "activity": "L-arginyl-[protein] + S-adenosyl-L-methionine = N(omega)-methyl-L-arginyl-[protein] + S-adenosyl-L-homocysteine + H(+).", "evidence": [ { "id": "A0A8V0ZYF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZYF3" } ] }, { "ec_number": "2.1.1.321", "activity": "", "evidence": [ { "id": "A0A8V0ZYF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZYF3" } ] } ] }, { "uniprot_ac": "F1NJK8", "gene_name": "PRMT1", "activity": [ { "ec_number": "2.1.1.319", "activity": "L-arginyl-[protein] + 2 S-adenosyl-L-methionine = N(omega),N(omega)-dimethyl-L-arginyl-[protein] + 2 S-adenosyl-L-homocysteine + 2 H(+).", "evidence": [ { "id": "F1NJK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NJK8" } ] }, { "ec_number": "2.1.1.319", "activity": "", "evidence": [ { "id": "F1NJK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NJK8" } ] } ] }, { "uniprot_ac": "Q5ZIB9", "gene_name": "PRMT7", "activity": [ { "ec_number": "2.1.1.321", "activity": "L-arginyl-[protein] + S-adenosyl-L-methionine = N(omega)-methyl-L-arginyl-[protein] + S-adenosyl-L-homocysteine + H(+).", "evidence": [ { "id": "Q5ZIB9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZIB9" } ] }, { "ec_number": "2.1.1.321", "activity": "", "evidence": [ { "id": "Q5ZIB9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZIB9" } ] } ] } ], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1NJK8-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 394, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1NJK8-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1NJK8" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1NJK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NJK8" }, { "id": "PF22528", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22528" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Protein arginine N-methyltransferase", "eco_id": "ECO_0000259", "start_pos": 217, "end_pos": 381, "start_aa": "Asp", "end_aa": "Gln", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.1.1.319", "ec_name": "L-arginyl-[protein] + 2 S-adenosyl-L-methionine = N(omega),N(omega)-dimethyl-L-arginyl-[protein] + 2 S-adenosyl-L-homocysteine + 2 H(+).", "evidence": [ { "id": "2.1.1.319", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.319" }, { "id": "2.1.1.319", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.1.1.319" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 37 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { 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Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052539.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_025008977", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025008977" } ] }, { "annotation": "NADH-cytochrome b5 reductases are involved in desaturation and elongation of fatty acids, cholesterol biosynthesis, drug metabolism, and, in erythrocyte, methemoglobin reduction.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AA34", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA34#function" }, { "database": "UniProtKB", "id": "ARBA00055239", "url": "https://www.uniprot.org/uniprotkb/ARBA00055239#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NPT9", "url": "https://www.uniprot.org/uniprotkb/F1NPT9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LOC112529965", "url": "https://www.uniprot.org/uniprotkb/F1NPT9", "locus": {} } ], "crossref": [ { "id": "F1NPT9", "url": "https://alphafold.ebi.ac.uk/entry/F1NPT9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000010758", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000010758", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd06183", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06183", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "112529965", "url": "https://www.ncbi.nlm.nih.gov/gene/112529965", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001433", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001433", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001709", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001709", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001834", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001834", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008333", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008333", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017927", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017927", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017938", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017938", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019180", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019180", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039261", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039261", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:112529965", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:112529965", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YSPYWTD", "url": "https://omabrowser.org/oma/group/YSPYWTD/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A4Z7", "url": "https://www.orthodb.org/?gene=A0A8V1A4Z7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AA34", "url": "https://www.orthodb.org/?gene=A0A8V1AA34", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NPT9", "url": "https://www.orthodb.org/?gene=F1NPT9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR19370", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19370", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19370:SF184", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19370:SF184", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00175", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00175", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00970", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00970", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF09791", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09791", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-1237044", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1237044", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_025008977", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025008977", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "46680", "url": "https://www.rhea-db.org/rhea/46680", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V1A4Z7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4Z7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A4Z7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4Z7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AA34", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA34", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AA34-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA34-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NPT9", "url": "https://www.uniprot.org/uniprotkb/F1NPT9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NPT9-1", "url": "https://www.uniprot.org/uniprotkb/F1NPT9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSGSEEEWRALKPREPSPSQCCGGGCQPCVYDVYEQQLARWERARAARDKGLLVEGRGESGNSELSPDAFTAFSLSWVRQLTEDTYQCRFELPGNGSLRLGLGQHLVLRGVVNGLEVQRAYTPISPGNAEGYFEVLIKCYEAGLMSQYIKTWKEGDTAFWRGPFGGFPYRPNKHGELLMLASGTGLAPMLPILQSITDDEEDETFVTLVGCFCTFEKIYLKPLLQDLARYWNIRIFYVLSQETSKENLPWSYQENTYIGRLNEDLIRTVINSCRRKPFVLICGSSAFTEDMNRYLKAAGIEEDSCFVF", "length": 308, "header": "tr|F1NPT9-1|F1NPT9_CHICK Isoform 1 of NADH-cytochrome b5 reductase OS=Gallus gallus OX=9031 GN=LOC112529965 PE=3 SV=4 CANONICAL=F1NPT9-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A4Z7-1", "url": "https://www.uniprot.org/uniprotkb/F1NPT9/entry#A0A8V1A4Z7-1", "sequence": { "sequence": "MSGSEEEWRALKPREPSPSQCCGGGCQPCVYDVYEQQLARWERARAARDKGLLVEGRGESGNSELSPDAFTAFSLSWVRQLTEDTYQCRFELPGNGSLRLGLGQHLVLRAFHPKGSYSYSPAVTKECYEAGLMSQYIKTWKEGDTAFWRGPFGGFPYRPNKHGELLMLASGTGLAPMLPILQSITDDEEDETFVTLVGCFCTFEKIYLKPLLQDLARYWNIRIFYVLSQETSKENLPWSYQENTYIGRLNEDLIRTVINSCRRKPFVLICGSSAFTEDMNRYLKAAGIEEDSCFVF", "length": 296, "header": "tr|A0A8V1A4Z7-1|A0A8V1A4Z7_CHICK Computationally mapped isoform of Cytochrome b5 reductase like OS=Gallus gallus OX=9031 GN=LOC112529965 PE=4 SV=1 CANONICAL=F1NPT9-1" }, "locus": { "chromosome": "8", "start_pos": 24849878, "end_pos": 24841655, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010061966.1", "url": "https://www.ensembl.org/id/ENSGALT00010061966.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038263.1", "url": "https://www.ensembl.org/id/ENSGALP00010038263.1" } ] } }, { "isoform_ac": "A0A8V1AA34-1", "url": "https://www.uniprot.org/uniprotkb/F1NPT9/entry#A0A8V1AA34-1", "sequence": { "sequence": "MSGSEEEWRALKPREPSPSQCCGGGCQPCVYDVYEQQLARWERARAARDKGLLVEGRGESGNSELSPDAFTAFSLSWVRQLTEDTYQCRFELPGNGSLRLGLGQHLVLRGVVNGLEVQRAYTPISPGNAEGYFEVLIKCYEAGLMSQYIKTWKEGDTAFWRGPFGGFPYRPNKQLR", "length": 176, "header": "tr|A0A8V1AA34-1|A0A8V1AA34_CHICK Computationally mapped isoform of NADH-cytochrome b5 reductase-like OS=Gallus gallus OX=9031 GN=LOC112529965 PE=3 SV=1 CANONICAL=F1NPT9-1" }, "locus": { "chromosome": "8", "start_pos": 24849878, "end_pos": 24844703, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010061963.1", "url": "https://www.ensembl.org/id/ENSGALT00010061963.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038260.1", "url": "https://www.ensembl.org/id/ENSGALP00010038260.1" } ] } }, { "isoform_ac": "F1NPT9-1", "url": "https://www.uniprot.org/uniprotkb/F1NPT9/entry#F1NPT9-1", "sequence": { "sequence": "MSGSEEEWRALKPREPSPSQCCGGGCQPCVYDVYEQQLARWERARAARDKGLLVEGRGESGNSELSPDAFTAFSLSWVRQLTEDTYQCRFELPGNGSLRLGLGQHLVLRGVVNGLEVQRAYTPISPGNAEGYFEVLIKCYEAGLMSQYIKTWKEGDTAFWRGPFGGFPYRPNKHGELLMLASGTGLAPMLPILQSITDDEEDETFVTLVGCFCTFEKIYLKPLLQDLARYWNIRIFYVLSQETSKENLPWSYQENTYIGRLNEDLIRTVINSCRRKPFVLICGSSAFTEDMNRYLKAAGIEEDSCFVF", "length": 308, "header": "tr|F1NPT9-1|F1NPT9_CHICK Isoform 1 of NADH-cytochrome b5 reductase OS=Gallus gallus OX=9031 GN=LOC112529965 PE=3 SV=4 CANONICAL=F1NPT9-1" }, "locus": { "chromosome": "8", "start_pos": 24849878, "end_pos": 24841655, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010061967.1", "url": "https://www.ensembl.org/id/ENSGALT00010061967.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038264.1", "url": "https://www.ensembl.org/id/ENSGALP00010038264.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "gga:112529965", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:112529965", "resource": "KEGG Pathway" }, { "id": "R-GGA-1237044", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1237044", "resource": "Reactome", "description": "Erythrocytes take up carbon dioxide and release oxygen" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8W4FMV2-1", "protein_name": "NADH-cytochrome b5 reductase", "gene_name": "CYB5RL", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MMAEREEDEEEAWLQLRPVEPLPSQCCGSGCSPCVFDLYQRDLARWEAARASKDRSLLRGSTSQSCPSELNPETFMAFRISAVDRLSKDTYLVRFALPGNSQLGLRPGQHLILRGTVDDLEIQRAYTPISPANTEGYFEVLIKCYQTGLMSQCVKSWRVGDAAFWRGPFGSFCYKPNQYGELLMLAAGTGLAPMVPILQSITDNAEDETFVTLVGCFKTFEGIYLKAFLQEQARFWNVRTFFVLSQENSPEQLPWSYRDKTRFGRLGQDLVDELVGSCRRKPFALVCGSAEFTQDVARCLLSAGLAEDAYFLF", "length": 313 }, "evidence": [ { "id": "F1NPT9", "url": "https://omabrowser.org/oma/group/F1NPT9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0AAA9SH94-1", "protein_name": "NADH-cytochrome b5 reductase", "gene_name": "CYB5RL", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MMDQGEEGDEEEAWLQLRPVEPLPSQCCGSGCSPCVFDIYQRDLARWEAARASKDRSLLSREETQSCPSKLSPETFLAFLISAVDRLTEDTYLVRFALPGNSQLGLRPGQHLILRGTVDDLEIQRAYTPISPANAEGYFEVLIKCYQTGLMSRYVKSWKAGDTAFWRGPFGGFFYKPNQYGELLMLAAGTGLAPMVPILQSITDNAEDETFITLVGCFKTFEGIYLKTFLQEQARFWNVRTFFVLSQENSLEQLPWSYRDRTRFGRLDRDLLEELVGSCRRKPFALVCGSAEFTKDMAGYLLHAGLAEDSYFLF", "length": 314 }, "evidence": [ { "id": "F1NPT9", "url": "https://omabrowser.org/oma/group/F1NPT9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "B1AS42-1", "protein_name": "NADH-cytochrome b5 reductase-like", "gene_name": "Cyb5rl", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAETEEEEDSEAWLRLKPVEPLPSQCCGSGCSPCVFDLYYRDLERWETARARNDRSLLSGKQPPESQSCSAKLSPETFLAFHISTMEKVTKDTYLVRFTLPGNSRLGLRPGQHLILRGVVDGLEIQRAYTPISPVTAEGYFDVLIKCYRTGLMSQYVESWRTGDTAFWRGPFGSFLYEPKKYGELLMLAAGTGLAPMVPILQSITDDEDDETFVTLVGCFKTFEGIYLKTFFQEQARFWNVQTFFVLSQEVSPEQLPWSYRDKTHFGRLGQELVAELVACCRRKPFTLVCGSPAFNEDMARCLLSAGLTEDSYFLF", "length": 316 }, "evidence": [ { "id": "F1NPT9", "url": "https://omabrowser.org/oma/group/F1NPT9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "G3GTL8-1", "protein_name": "NADH-cytochrome b5 reductase-like", "gene_name": "LOC100753272", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MDQRVDNDAEAWLQLKPVEPLPSQCCGSGCSPCVFDLYSRDLERWEAARARNDRSLLSGKQSPETQGCSTKLSPETFLAFHISAIEKLTKDTLRVRFTLPGNNQLGLHPGQHLILRGIADGLEIQRAYTPISPVTAEGYFDVLIKCYQAGLMSQYVESWRTGDTAFWRGPFGSFLYEPNKYGELLMLAAGTGLAPMVPILHSITDNADDETFVTLVCCFKTFESIYLKTFLQEQARFWNVRTFFVLSQEVSPEQLPWSYREKTHFGRLGQELVDELVACCRRKPFTLVCGSSSFTKDMARCLLSAGLTEDSYFLF", "length": 315 }, "evidence": [ { "id": "F1NPT9", "url": "https://omabrowser.org/oma/group/F1NPT9/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q6IPT4-1", "protein_name": "NADH-cytochrome b5 reductase-like", "gene_name": "CYB5RL", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MMAEREEDDDTEEAWMQLRPTEPLPSQCCGSGCSPCVFDLYHRDLARWEAAQASKDRSLLRGPESQSCPSKLNPETFVAFCIIAMDRLTKDTYRVRFALPGNSQLGLRPGQHLILRGIVDDLEIQRAYTPISPANAEGYFEVLIKCYQMGLMSRYVESWRVGDTAFWRGPFGDFFYKPNQYGELLLLAAGTGLAPMVPILQSITDNENDETFVTLVGCFKTFESIYLKTFLQEQARFWNVRTFFVLSQESSSEQLPWSYQEKTHFGHLGQDLIKELVSCCRRKPFALVCGSAEFTKDIARCLLCAGLTEDSYFLF", "length": 315 }, "evidence": [ { "id": "F1NPT9", "url": "https://omabrowser.org/oma/group/F1NPT9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VWK8-1", "protein_name": "FAD-binding FR-type domain-containing protein", "gene_name": "Dmel\\CG7914", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MLSYLEDLKENEDQLRDSDCCGNGCTNCILDNKPRPSKRVLLAGKRNVILSYTKFRLLRREALGPNGQLLLLHFAHAAEEGDGDGAVDTVLDIPPGHHVMLRVGSLLRPYSPYWSDFVAKEFRILVKLQPEGPMSRHLQAVQPDDLLEFRGPIGQYVHEPQPAKCIYIIAQGVAIAPTLPLVRQVLDNEEDMSRLWHLVCAHDLLHVYFREEMLEFAQFWNYRSCLYLPHQQCDSSACQEAGHCAQQCPQLRDNLRYKETAKVSRLDATELATHLNPAIPGQRVLIVAGDSSFQKNIAQIATQSLDVDPANIYML", "length": 315 }, "evidence": [ { "id": "F1NPT9", "url": "https://omabrowser.org/oma/group/F1NPT9/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "cytochrome-b5 reductase activity, acting on NADH", "id": "GO:0090524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090524", "evidence": [ { "database": "UniProtKB", "id": "F1NPT9", "url": "https://www.uniprot.org/uniprotkb/F1NPT9" } ], "pmid": "" }, { "name": "oxidoreductase activity", "id": "GO:0016491", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016491", "evidence": [ { "database": "UniProtKB", "id": "F1NPT9", "url": "https://www.uniprot.org/uniprotkb/F1NPT9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 95, "end_pos": 97, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "46680", "name": "", "equation": "2 Fe(III)-[cytochrome b5] + NADH = 2 Fe(II)-[cytochrome b5] + NAD(+) + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q5ZHX7-1", "A0A8V0X9V6-1", "E1C034-1", "A0A8V0ZKC7-1", "F1NPT9-1" ], "evidence": [ { "id": "46680", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/46680" } ] }, { "id": "R-GGA-6806831", "name": "CYB5Rs reduce MetHb to HbA", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, endoplasmic reticulum membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0X9V6-1", "F1NPT9-1", "A0A8V0ZKC7-1" ], "evidence": [ { "id": "R-GGA-6806831", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6806831" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A8V0X9V6", "gene_name": "CYB5R4", "activity": [ { "ec_number": "1.6.2.2", "activity": "2 Fe(III)-[cytochrome b5] + NADH = 2 Fe(II)-[cytochrome b5] + NAD(+) + H(+).", "evidence": [ { "id": "A0A8V0X9V6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X9V6" } ] }, { "ec_number": "1.6.2.2", "activity": "", "evidence": [ { "id": "A0A8V0X9V6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X9V6" } ] } ] }, { "uniprot_ac": "A0A8V0ZKC7", "gene_name": "CYB5R2", "activity": [ { "ec_number": "1.6.2.2", "activity": "2 Fe(III)-[cytochrome b5] + NADH = 2 Fe(II)-[cytochrome b5] + NAD(+) + H(+).", "evidence": [ { "id": "A0A8V0ZKC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKC7" } ] }, { "ec_number": "1.6.2.2", "activity": "", "evidence": [ { "id": "A0A8V0ZKC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKC7" } ] } ] }, { "uniprot_ac": "E1C034", "gene_name": "A4GALT", "activity": [ { "ec_number": "2.4.1.228", "activity": "a beta-D-Gal-(1->4)-beta-D-Glc-(1<->1)-Cer(d18:1(4E)) + UDP-alpha-D-galactose = a globoside Gb3Cer (d18:1(4E)) + UDP + H(+).", "evidence": [ { "id": "E1C034", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C034" } ] }, { "ec_number": "2.4.1.228", "activity": "", "evidence": [ { "id": "E1C034", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C034" } ] }, { "ec_number": "1.6.2.2", "activity": "2 Fe(III)-[cytochrome b5] + NADH = 2 Fe(II)-[cytochrome b5] + NAD(+) + H(+).", "evidence": [ { "id": "E1C034", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C034" } ] }, { "ec_number": "1.6.2.2", "activity": "", "evidence": [ { "id": "E1C034", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C034" } ] } ] }, { "uniprot_ac": "F1NPT9", "gene_name": "LOC112529965", "activity": [ { "ec_number": "1.6.2.2", "activity": "2 Fe(III)-[cytochrome b5] + NADH = 2 Fe(II)-[cytochrome b5] + NAD(+) + H(+).", "evidence": [ { "id": "F1NPT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NPT9" } ] }, { "ec_number": "1.6.2.2", "activity": "", "evidence": [ { "id": "F1NPT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NPT9" } ] } ] }, { "uniprot_ac": "Q5ZHX7", "gene_name": "CYB5R2", "activity": [ { "ec_number": "1.6.2.2", "activity": "2 Fe(III)-[cytochrome b5] + NADH = 2 Fe(II)-[cytochrome b5] + NAD(+) + H(+).", "evidence": [ { "id": "Q5ZHX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZHX7" } ] }, { "ec_number": "1.6.2.2", "activity": "", "evidence": [ { "id": "Q5ZHX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZHX7" } ] } ] } ], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1NPT9-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 308, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1NPT9-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1NPT9" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "1.6.2.2", "ec_name": "2 Fe(III)-[cytochrome b5] + NADH = 2 Fe(II)-[cytochrome b5] + NAD(+) + H(+).", "evidence": [ { "id": "1.6.2.2", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:1.6.2.2" }, { "id": "1.6.2.2", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=1.6.2.2" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 95, "end_pos": 97 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1NRM8-1", "uniprot_ac": "F1NRM8", "uniprot_id": "F1NRM8_CHICK", "mass": { "chemical_mass": 28191.0, "monoisotopic_mass": 28191.0 }, "refseq": {}, "gene_names": [ { "name": "ERP29", "type": "recommended", "evidence": [ { "id": "F1NRM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NRM8" } ] } ], "protein_names": [ { "name": "Endoplasmic reticulum protein 29", "type": "synonym", "evidence": [ { "id": "F1NRM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NRM8/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NRM8", "url": "https://www.uniprot.org/uniprotkb/F1NRM8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ERP29", "url": "https://www.uniprot.org/uniprotkb/F1NRM8", "locus": { "chromosome": "15", "start_pos": 6275961, "end_pos": 6280033, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010025938", "url": "https://www.ensembl.org/id/ENSGALG00010025938" } ] } } ], "crossref": [ { "id": "F1NRM8", "url": "https://alphafold.ebi.ac.uk/entry/F1NRM8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000023510", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000023510", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00238", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00238", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd03007", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03007", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "416882", "url": "https://www.ncbi.nlm.nih.gov/gene/416882", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011679", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011679", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012883", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012883", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016855", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016855", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036249", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036249", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036356", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036356", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:416882", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416882", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "FPYGDKH", "url": "https://omabrowser.org/oma/group/FPYGDKH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AC42", "url": "https://www.orthodb.org/?gene=A0A8V1AC42", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NRM8", "url": "https://www.orthodb.org/?gene=F1NRM8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12211", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12211", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12211:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12211:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07749", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07749", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07912", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07912", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001263253", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001263253", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1AC42", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC42", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AC42-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC42-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NRM8", "url": "https://www.uniprot.org/uniprotkb/F1NRM8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NRM8-1", "url": "https://www.uniprot.org/uniprotkb/F1NRM8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAAAAAGSLLLCLLGLALPGSALHTKGSVPLDTITFYKVIPKHKFVLVKFDTQYPYGEKQDEFKKLAESSGSSEDLLVAEVGISDYGDKLNTELGEKYKLDKEKYPIFYLFQDGDFDNPLPYSGHIKAGAIQRWLKSNGIYLGMPGCLKEYDVLASKFMSVTDKSERQSLLKKGQQSLEKAKETEKKSAEQYLKIMSKILEQGEEFAANEVVRITKLIEKNKMSDGKKEELQKSLNILASFLKKNNEKDEL", "length": 252, "header": "tr|F1NRM8-1|F1NRM8_CHICK Isoform 1 of Endoplasmic reticulum protein 29 OS=Gallus gallus OX=9031 GN=ERP29 PE=1 SV=3 CANONICAL=F1NRM8-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AC42-1", "url": "https://www.uniprot.org/uniprotkb/F1NRM8/entry#A0A8V1AC42-1", "sequence": { "sequence": "SSAVTDLFGRSKDTAFYNPSTILCGQQEREVIPKHKFVLVKFDTQYPYGEKQDEFKKLAESSGSSEDLLVAEVGISDYGDKLNTELGEKYKLDKEKYPIFYLFQDGDFDNPLPYSGHIKAGAIQRWLKSNGIYLGMPGCLKEYDVLASKFMSVTDKSERQSLLKKGQQSLEKAKETEKKSAEQYLKIMSKILEQGEEFAANEVVRITKLIEKNKMSDGKKEELQKSLNILASFLKKNNEKDEL", "length": 243, "header": "tr|A0A8V1AC42-1|A0A8V1AC42_CHICK Computationally mapped isoform of Endoplasmic reticulum resident protein 29 OS=Gallus gallus OX=9031 GN=ERP29 PE=1 SV=1 CANONICAL=F1NRM8-1" }, "locus": { "chromosome": "15", "start_pos": 6279402, "end_pos": 6277093, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010063229.1", "url": "https://www.ensembl.org/id/ENSGALT00010063229.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039030.1", "url": "https://www.ensembl.org/id/ENSGALP00010039030.1" } ] } }, { "isoform_ac": "F1NRM8-1", "url": "https://www.uniprot.org/uniprotkb/F1NRM8/entry#F1NRM8-1", "sequence": { "sequence": "MAAAAAAGSLLLCLLGLALPGSALHTKGSVPLDTITFYKVIPKHKFVLVKFDTQYPYGEKQDEFKKLAESSGSSEDLLVAEVGISDYGDKLNTELGEKYKLDKEKYPIFYLFQDGDFDNPLPYSGHIKAGAIQRWLKSNGIYLGMPGCLKEYDVLASKFMSVTDKSERQSLLKKGQQSLEKAKETEKKSAEQYLKIMSKILEQGEEFAANEVVRITKLIEKNKMSDGKKEELQKSLNILASFLKKNNEKDEL", "length": 252, "header": "tr|F1NRM8-1|F1NRM8_CHICK Isoform 1 of Endoplasmic reticulum protein 29 OS=Gallus gallus OX=9031 GN=ERP29 PE=1 SV=3 CANONICAL=F1NRM8-1" }, "locus": { "chromosome": "15", "start_pos": 6280006, "end_pos": 6277093, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010063232.1", "url": "https://www.ensembl.org/id/ENSGALT00010063232.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039033.1", "url": "https://www.ensembl.org/id/ENSGALP00010039033.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:416882", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416882", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "F1RJM2-1", "protein_name": "Endoplasmic reticulum resident protein 29", "gene_name": "ERP29", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MASAIPHAACLSPLFPLLLFLLFLSAPQGGSGLHTKGALPLDTITFYKVIPKSKFVLVKFDTQYPYGEKQDEFKRLAENSASSDDLLVAEVGISDYGDKLNMELSEKYKLDKENYPVFYLFRDGDFENPILYSGAVKVGAIQRWLKGHGIYLGMPGCLPAYDTLAGEFIRASGVEARQALLRQGQDNLKSVKETEKKWAEQYLKIMGKILDQGEDFPASEMTRITKLIEKNKMSSGKKEELQRSLNILTAFQKKGAEKEEL", "length": 261 }, "evidence": [ { "id": "F1NRM8", "url": "https://omabrowser.org/oma/group/F1NRM8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3H284-1", "protein_name": "Endoplasmic reticulum resident protein 29", "gene_name": "Erp29", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAASVPAAVSLSPLLSILLGLLLLSAPPGGSGLHTKGALPLDTITFYKVIPKSKFVLVKFDTQYPYGEKQDEFKRLAENSASSDDLLVAEVGISDYGDKLNMELSEKYKLDKENYPVFYLFRDGDFENPIPYSGAIKVGAIQRWLKGQGVYLGMPGCLPAYDALAGEFIKASSIEARQAILKQGQDGLSGVKETEKKWASQYLKIMGKILDHGEDFPASETNRIGKLIENKMSDSKKEELQKSLNILTAFRKKGAEKEEL", "length": 260 }, "evidence": [ { "id": "F1NRM8", "url": "https://omabrowser.org/oma/group/F1NRM8/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "O44342-1", "protein_name": "Protein windbeutel", "gene_name": "wbl", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MMHILVTLLLVAIHSIPTTWAVTCTGCVDLDELSFEKTVERFPYSVVKFDIAYPYGEKHEAFTAFSKSAHKATKDLLIATVGVKDYGELENKALGDRYKVDDKNFPSIFLFKGNADEYVQLPSHVDVTLDNLKAFVSANTPLYIGRDGCIKEFNEVLKNYANIPDAEQLKLIEKLQAKQEQLTDPEQQQNARAYLIYMRKIHEVGYDFLEEETKRLLRLKAGKVTEAKKEELLRKLNILEVFRVHKVTKTAPEKEEL", "length": 257 }, "evidence": [ { "id": "F1NRM8", "url": "https://omabrowser.org/oma/group/F1NRM8/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "P30040-1", "protein_name": "Endoplasmic reticulum resident protein 29", "gene_name": "ERP29", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAAVPRAAFLSPLLPLLLGFLLLSAPHGGSGLHTKGALPLDTVTFYKVIPKSKFVLVKFDTQYPYGEKQDEFKRLAENSASSDDLLVAEVGISDYGDKLNMELSEKYKLDKESYPVFYLFRDGDFENPVPYTGAVKVGAIQRWLKGQGVYLGMPGCLPVYDALAGEFIRASGVEARQALLKQGQDNLSSVKETQKKWAEQYLKIMGKILDQGEDFPASEMTRIARLIEKNKMSDGKKEELQKSLNILTAFQKKGAEKEEL", "length": 261 }, "evidence": [ { "id": "F1NRM8", "url": "https://omabrowser.org/oma/group/F1NRM8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P52555-1", "protein_name": "Endoplasmic reticulum resident protein 29", "gene_name": "Erp29", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAAAVPGAVSLSPLLSVLLGLLLLSAPHGASGLHTKGALPLDTVTFYKVIPKSKFVLVKFDTQYPYGEKQDEFKRLAENSASSDDLLVAEVGISDYGDKLNMELSEKYKLDKESYPVFYLFRDGDFENPVPYSGAVKVGAIQRWLKGQGVYLGMPGCLPAYDALAGQFIEASSREARQAILKQGQDGLSGVKETDKKWASQYLKIMGKILDQGEDFPASELARISKLIENKMSEGKKEELQRSLNILTAFRKKGAEKEEL", "length": 260 }, "evidence": [ { "id": "F1NRM8", "url": "https://omabrowser.org/oma/group/F1NRM8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P57759-1", "protein_name": "Endoplasmic reticulum resident protein 29", "gene_name": "Erp29", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAAAGVSGAASLSPLLSVLLGLLLLFAPHGGSGLHTKGALPLDTVTFYKVIPKSKFVLVKFDTQYPYGEKQDEFKRLAENSASSEELLVAEVGISDYGDKLNMELSEKYKLDKESYPVFYLFRDGDLENPVLYNGAVKVGAIQRWLKGQGVYLGMPGCLPAYDALAGEFIKASSIEARQAILKQGQDGLLSVKETEKKWASQYLKIMGKILDQGEDFPASEMARIGKLIENKMSDSKKEELQKSLNILTAFRKKEAEKEEL", "length": 262 }, "evidence": [ { "id": "F1NRM8", "url": "https://omabrowser.org/oma/group/F1NRM8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "endoplasmic reticulum lumen", "id": "GO:0005788", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005788", "evidence": [ { "database": "UniProtKB", "id": "F1NRM8", "url": "https://www.uniprot.org/uniprotkb/F1NRM8" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "F1NRM8", "url": "https://www.uniprot.org/uniprotkb/F1NRM8" } ], "pmid": "" }, { "name": "cell surface", "id": "GO:0009986", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009986", "evidence": [ { "database": "UniProtKB", "id": "F1NRM8", "url": "https://www.uniprot.org/uniprotkb/F1NRM8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "protein secretion", "id": "GO:0009306", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009306", "evidence": [ { "database": "UniProtKB", "id": "F1NRM8", "url": "https://www.uniprot.org/uniprotkb/F1NRM8" } ], "pmid": "" }, { "name": "negative regulation of protein secretion", "id": "GO:0050709", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050709", "evidence": [ { "database": "UniProtKB", "id": "F1NRM8", "url": "https://www.uniprot.org/uniprotkb/F1NRM8" } ], "pmid": "" }, { "name": "positive regulation of gene expression", "id": "GO:0010628", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010628", "evidence": [ { "database": "UniProtKB", "id": "F1NRM8", "url": "https://www.uniprot.org/uniprotkb/F1NRM8" } ], "pmid": "" }, { "name": "negative regulation of gene expression", "id": "GO:0010629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010629", "evidence": [ { "database": "UniProtKB", "id": "F1NRM8", "url": "https://www.uniprot.org/uniprotkb/F1NRM8" } ], "pmid": "" }, { "name": "positive regulation of MAPK cascade", "id": "GO:0043410", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043410", "evidence": [ { "database": "UniProtKB", "id": "F1NRM8", "url": "https://www.uniprot.org/uniprotkb/F1NRM8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1NRM8-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 252, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1NRM8-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1NRM8" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1NRM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NRM8" }, { "id": "PF07912", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07912" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "ERp29 N-terminal", "eco_id": "ECO_0000259", "start_pos": 24, "end_pos": 146, "start_aa": "Leu", "end_aa": "Pro", "glycosite_overlap": "" }, { "evidence": [ { "id": "F1NRM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NRM8" }, { "id": "PF07749", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07749" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Endoplasmic reticulum resident protein 29 C-terminal", "eco_id": "ECO_0000259", "start_pos": 147, "end_pos": 242, "start_aa": "Gly", "end_aa": "Phe", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1NLT2-1", "uniprot_ac": "F1NLT2", "uniprot_id": "F1NLT2_CHICK", "mass": { "chemical_mass": 59088.0, "monoisotopic_mass": 59088.0 }, "refseq": { "ac": "XP_004945846", "name": "torsin-4A", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004945846" }, "gene_names": [ { "name": "TOR4A", "type": "recommended", "evidence": [ { "id": "F1NLT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NLT2" } ] }, { "name": "TOR4A", "type": "synonym", "evidence": [ { "id": "XP_004945846", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004945846" } ] } ], "protein_names": [ { "name": "Torsin family 4 member A", "type": "synonym", "evidence": [ { "id": "F1NLT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NLT2/entry#names_and_taxonomy" } ] }, { "name": "torsin-4A", "type": "synonym", "evidence": [ { "id": "XP_004945846", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004945846" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 1% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052548.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004945846", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004945846" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NLT2", "url": "https://www.uniprot.org/uniprotkb/F1NLT2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TOR4A", "url": "https://www.uniprot.org/uniprotkb/F1NLT2", "locus": { "chromosome": "17", "start_pos": 2478018, "end_pos": 2469208, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010027896", "url": "https://www.ensembl.org/id/ENSGALG00010027896" } ] } } ], "crossref": [ { "id": "ENSGALG00000008623", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000008623", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "417257", "url": "https://www.ncbi.nlm.nih.gov/gene/417257", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR010448", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010448", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024829", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024829", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR049337", "url": "https://www.ebi.ac.uk/interpro/entry/IPR049337", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:417257", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417257", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "EFAITGC", "url": "https://omabrowser.org/oma/group/EFAITGC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ADR2", "url": "https://www.orthodb.org/?gene=A0A8V1ADR2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NLT2", "url": "https://www.orthodb.org/?gene=F1NLT2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10760", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10760", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10760:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10760:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF06309", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06309", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21376", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21376", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-114608", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-114608", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_004945846", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004945846", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1ADR2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADR2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ADR2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADR2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NLT2", "url": "https://www.uniprot.org/uniprotkb/F1NLT2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NLT2-1", "url": "https://www.uniprot.org/uniprotkb/F1NLT2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDGELLGTEVDGEAPTAMGDVGGEASCAEGDAKGEVSCAEVGGELPTAMGDAAEEASCAESGAKEEGPYADGHVEGEMGCSDSDGEGELRCATTDVKEEASCSESEGEEVPDAEIPAASKRVSFISSPLRAIVRLKQRYRVQKKGRLHFELPQEKSSEPVHARVLQRQFSLNRSGLYGSSKSFFNQSGFKTSQYFTFDTSVEEWAMSKPRRKKKRRKSRVVLYPDKTKRYLPAEEKSNAKRCLLLLIVIIFFQILNAIENLDDNLQKYDLDGLEKTMHREVFGQKLAVESIMQLLKDYLATHIHNKPLVLSLNGPTGVGKSHVGWLLAKHFRSVMDNDFVLQYFVMHHCPSGAAPLTCETDLSKKISDMVTRAEIEEKIPLFILDEVELMSPVLLDTLSRFFEPNQTNEFLNAIYILISNIGGGEITKFVIQNASAELLQQRSGAEELLSVIQPVLTHTHPLWKAADVVPFVLLERSHVIDCFLEEMRREGLYPEQSHVERLASQLSYYTTGDKQFSRLGCKQVVAKVNLL", "length": 531, "header": "tr|F1NLT2-1|F1NLT2_CHICK Isoform 1 of Torsin family 4 member A OS=Gallus gallus OX=9031 GN=TOR4A PE=1 SV=5 CANONICAL=F1NLT2-1" }, "isoforms": [ { "isoform_ac": "A0A8V1ADR2-1", "url": "https://www.uniprot.org/uniprotkb/F1NLT2/entry#A0A8V1ADR2-1", "sequence": { "sequence": "MDGELLGTEVDGEAPTAMGDVGGEASCAEGDAKGEASCAESGAKEEGPYADGHVEGEMGCSDSDGEGELRCATTDVKEEASCSESEGEEVPDAEIPAASKRVSFISSPLRAIVRLKQRYRVQKKGRLHFELPQEKSSEPVHARVLQRQFSLNRSGLYGSSKSFFNQSGFKTSQYFTFDTSVEEWAMSKPRRKKKRRKSRVVLYPDKTKRYLPAEEKSNAKRCLLLLIVIIFFQILNAIENLDDNLQKYDLDGLEKTMHREVFGQKLAVESIMQLLKDYLATHIHNKPLVLSLNGPTGVGKSHVGWLLAKHFRSVMDNDFVLQYFVMHHCPSGAAPLTCETDLSKKISDMVTRAEIEEKIPLFILDEVELMSPVLLDTLSRFFEPNQTNEFLNAIYILISNIGGGEITKFVIQNASAELLQQRSGAEELLSVIQPVLTHTHPLWKAADVVPFVLLERSHVIDCFLEEMRREGLYPEQSHVERLASQLSYYTTGDKQFSRLGCKQVVAKVNLL", "length": 511, "header": "tr|A0A8V1ADR2-1|F1NLT2_CHICK Computationally mapped isoform of Torsin family 4 member A OS=Gallus gallus OX=9031 GN=TOR4A PE=1 SV=1 CANONICAL=F1NLT2-1" }, "locus": { "chromosome": "17", "start_pos": 2476015, "end_pos": 2474423, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067624.1", "url": "https://www.ensembl.org/id/ENSGALT00010067624.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041367.1", "url": "https://www.ensembl.org/id/ENSGALP00010041367.1" } ] } }, { "isoform_ac": "F1NLT2-1", "url": "https://www.uniprot.org/uniprotkb/F1NLT2/entry#F1NLT2-1", "sequence": { "sequence": "MDGELLGTEVDGEAPTAMGDVGGEASCAEGDAKGEVSCAEVGGELPTAMGDAAEEASCAESGAKEEGPYADGHVEGEMGCSDSDGEGELRCATTDVKEEASCSESEGEEVPDAEIPAASKRVSFISSPLRAIVRLKQRYRVQKKGRLHFELPQEKSSEPVHARVLQRQFSLNRSGLYGSSKSFFNQSGFKTSQYFTFDTSVEEWAMSKPRRKKKRRKSRVVLYPDKTKRYLPAEEKSNAKRCLLLLIVIIFFQILNAIENLDDNLQKYDLDGLEKTMHREVFGQKLAVESIMQLLKDYLATHIHNKPLVLSLNGPTGVGKSHVGWLLAKHFRSVMDNDFVLQYFVMHHCPSGAAPLTCETDLSKKISDMVTRAEIEEKIPLFILDEVELMSPVLLDTLSRFFEPNQTNEFLNAIYILISNIGGGEITKFVIQNASAELLQQRSGAEELLSVIQPVLTHTHPLWKAADVVPFVLLERSHVIDCFLEEMRREGLYPEQSHVERLASQLSYYTTGDKQFSRLGCKQVVAKVNLL", "length": 531, "header": "tr|F1NLT2-1|F1NLT2_CHICK Isoform 1 of Torsin family 4 member A OS=Gallus gallus OX=9031 GN=TOR4A PE=1 SV=5 CANONICAL=F1NLT2-1" }, "locus": { "chromosome": "17", "start_pos": 2476015, "end_pos": 2474423, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067630.1", "url": "https://www.ensembl.org/id/ENSGALT00010067630.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041373.1", "url": "https://www.ensembl.org/id/ENSGALP00010041373.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:417257", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417257", "resource": "KEGG Pathway" }, { "id": "R-GGA-114608", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-114608", "resource": "Reactome", "description": "Platelet degranulation" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZG57-1", "protein_name": "Torsin-4A", "gene_name": "Tor4a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDRGHPSLEPQAKGPCVIAPVRAVLRLRRRVCVLRKRRLLQTGTEPSVGTGTLGSSASLGTLRADLDQPKFFTFDSLTELSSRTPRKRRRRSRVVLYPETSRKCRPRTERQSRAQRCLLLLVAIVGFQVLNAIENLDDNAQRYDLDGLEKALQRSVFGQPAAVSRIMALLRDYLATHVHSHPLLLALHGPSGVGKSHVGRLLARHFRAVLEDGALVLQYHARHHCPELRPVQDCRKELAQRVADVVAQAEAEEKTPLLVLDEAELLPPALLDELHDLLQPQRSHHFHNAIYVLLSGAGGIEITHFVLQNASRMLPSLRHSVGRTQTEESPALEELQTSLRELLAREHPLWHTAAIVPFLLLDKPDVVNCFREEMAGEGFFPEQAQAEHLAEQLSYYHVAGHEFAITGCKQVVAKVNLLQHKPAHAGHESVGPGV", "length": 434 }, "evidence": [ { "id": "F1NLT2", "url": "https://omabrowser.org/oma/group/F1NLT2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1RVY0-1", "protein_name": "Torsin-4A", "gene_name": "TOR4A", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDRGQPSPEPAAAAPARGPNVIAPVRAVVRLRRRVCLLRTRRLPTPGAGPDFGPGAPRANLHQPQFFTFEGPAELSSRAPRKRRRRSRVVLYPETSRKYRPQAERRSRAQRCLLLLVAIVGFQVLNAIENLDDNALRYDLDGLEKALQRAVFGQPSAVGRIVALLRDYLATHVHSRPLLLALHGPSGVGKSHVGRLLARHFRAVLEDSALVLQYDARHHCPDPRAAQDCREELAQRVADVVARAEAEEKTPLLVLDEVELLPQALLDELHGFLQPQRSHHFHNAIYVLLSGAGGAEVTRFVLQNASRALALRPDGAHGARAAAMAAQAEEELRVRLQALLVREHPLWQAAAIVPFLLLDKRDVVNCFRDEMAGEGFFPEQAHAELLAARLSYYRVAGREFAVTGCKQVVATVNLL", "length": 415 }, "evidence": [ { "id": "F1NLT2", "url": "https://omabrowser.org/oma/group/F1NLT2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3X7J5-1", "protein_name": "Torsin-4A", "gene_name": "TOR4A", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MDRGQSSPEPSAPVAPSPSVIAPVRAVVRLRHQVHLLRKRRPPSPAVAPDPGAAALRVPREQPQFFTFDGPAERASRPARKRRRRSRLVLYPETSRKFGPRAERQSRAQRCLLLLVAIVGFQVLNAIENLDDNALRYDLDGLEKTLQRAVFGQPAAVGRLVALLRDYLATHVHSRPLLLALHGPSGVGKSHVGRLLARHFRAVLEDGALVLQYHTRHHCPAPRAATGCREELARRVADVLARAEAEEKTPLLVLDDAELLPPALLDELHGLLQPQRPPRFHNAVYVLLSGAGGAEVTRFVLQNASRAGRADGAEELRAAEEELRASLHALLVRQHPLWEAAAIVPFLLLDKRDVVNCFRDEMAGEGFFPEQARAELLAAQLSYYRVAGREFAVNGCKQVVAAVNLL", "length": 406 }, "evidence": [ { "id": "F1NLT2", "url": "https://omabrowser.org/oma/group/F1NLT2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q568B8-1", "protein_name": "Torsin-4A", "gene_name": "tor4a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MGEQDPSDRLRGDQLKEPNQNGKGSFSQFSSSVRAMVRIRMKYQAIKKRRMEIASATPQIFTSPRSTSPKVFTFDNLHEPVNSNPASPRKRKKKRKGRVLYPTSSLRAVPTKESSRAKNCLYLLCIIVFLQVYNAIENLDDHVLKYDLEGLEKTLKREVFGQQEVAEGLLGHLQDYLSTYVHNKPLVLSFHGPTGVGKSHVGRLLAQHFRSVVGEELVMQYFVLHHCPTDDDIPVCTKSLESHISEMVSQGEEEEKIPVFIFDEVEHMPRQLMDTLRELIQPQNSNKYLNAIYILISNLGHEDITKFVLHNSSIAISGRLSLTQELTPWLRNYLQEHHGLFLDAEYLPFMLLEKSHVMDCFIDEMSREGFYPDRSHVERLAEELSYYIVGEREFSHTGCRQVVAKVNLL", "length": 409 }, "evidence": [ { "id": "F1NLT2", "url": "https://omabrowser.org/oma/group/F1NLT2/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q8BH02-1", "protein_name": "Torsin-4A", "gene_name": "Tor4a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDRSHPSLEPQAKGPCVIAPVRAVLRLRRRVCVLRKRRLLQPGTEPDSGTGTLGPTGSLGTLRADLDQPKFFTFDSLTELTSRTPRKRRRRSRVVLYPETSRKCRPRTERQSRAQRCLLLLVAIVGFQVLNAIENLDDNAQRYDLDGLEKALQRSVFGQPAAVGRIMALLRDYLATHVHSHPLLLALHGPSGVGKSHVGRLLARHFRAVLEDGALVLQYHARYHCPEPRPVQDCRKELAQRVADVVAQAEAEEKTPLLVLDEAELLPPALLDELHDLLQPQRSHHFHNAIYVLLSGAGGIEITHFVLQNASRMLPPLRHSAGSTQTEESPAQELLTSLRELLAREHPLWHTAAIVPFLLLDKPDVVNCFREEMAGEGFFPEQALAEHLAEQLSYYHVAGHEFAITGCKQVVAKVNLLQHKPAHAGH", "length": 426 }, "evidence": [ { "id": "F1NLT2", "url": "https://omabrowser.org/oma/group/F1NLT2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9NXH8-1", "protein_name": "Torsin-4A", "gene_name": "TOR4A", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDRGQPSLEPAAAAPRASGRCVIAPVRAVLRLRRRVCVLRKRRLLQPGGGPDVGTGAPRPGCSPRAPRADLDQPKFFTFDSPAELPSRTPRKKRRRSRLVLYPETSRKYRPRVEHRSRAQRCLLLLVAIVGFQVLNAIENLDDNAQRYDLDGLEKALQRAVFGQPAAVSRIVALMRDYLATHVHSRPLLLALHGPSGVGKSHVGRLLARHFRSVLEDSALVLQYHARHHCPEARAAQDCREELARRVADVVARAEAEEKTPLLVLDDVELMPRPLLDELHGFLQPQRSHHFHNAIYVLLSGAGGAEVTRFVLQNASRALPLRPDGFRSAEAAAAQAEEDLRASLLAVLSREHPLWQAAAIVPFLLLDKRDVVSCFRDEMAGEGFFPDQARAENLAAQLSFYRVAGREFAVTGCKQVVATVNLL", "length": 423 }, "evidence": [ { "id": "F1NLT2", "url": "https://omabrowser.org/oma/group/F1NLT2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "F1NLT2", "url": "https://www.uniprot.org/uniprotkb/F1NLT2" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "F1NLT2", "url": "https://www.uniprot.org/uniprotkb/F1NLT2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1NLT2", "url": "https://www.uniprot.org/uniprotkb/F1NLT2" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "F1NLT2", "url": "https://www.uniprot.org/uniprotkb/F1NLT2" } ], "pmid": "" }, { "name": "endomembrane system", "id": "GO:0012505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0012505", "evidence": [ { "database": "UniProtKB", "id": "F1NLT2", "url": "https://www.uniprot.org/uniprotkb/F1NLT2" } ], "pmid": "" }, { "name": "nuclear envelope", "id": "GO:0005635", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005635", "evidence": [ { "database": "UniProtKB", "id": "F1NLT2", "url": "https://www.uniprot.org/uniprotkb/F1NLT2" } ], "pmid": "" }, { "name": "endoplasmic reticulum lumen", "id": "GO:0005788", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005788", "evidence": [ { "database": "UniProtKB", "id": "F1NLT2", "url": "https://www.uniprot.org/uniprotkb/F1NLT2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "negative regulation of apoptotic process", "id": "GO:0043066", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043066", "evidence": [ { "database": "UniProtKB", "id": "F1NLT2", "url": "https://www.uniprot.org/uniprotkb/F1NLT2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 172, "end_pos": 174, "annotation": "n_glycosylation_sequon" }, { "start_pos": 185, "end_pos": 187, "annotation": "n_glycosylation_sequon" }, { "start_pos": 405, "end_pos": 407, "annotation": "n_glycosylation_sequon" }, { "start_pos": 433, "end_pos": 435, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1NLT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NLT2" }, { "id": "PF21376", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21376" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Torsin-1A C-terminal", "eco_id": "ECO_0000259", "start_pos": 474, "end_pos": 528, "start_aa": "Leu", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 172, "end_pos": 174 }, { "start_pos": 185, "end_pos": 187 }, { "start_pos": 405, "end_pos": 407 }, { "start_pos": 433, "end_pos": 435 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1NW80-1", "uniprot_ac": "F1NW80", "uniprot_id": "F1NW80_CHICK", "mass": { "chemical_mass": 27720.0, "monoisotopic_mass": 27720.0 }, "refseq": { "ac": "NP_001006222", "name": "Golgi SNAP receptor complex member 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006222" }, "gene_names": [ { "name": "GOSR1", "type": "recommended", "evidence": [ { "id": "F1NW80", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NW80" } ] }, { "name": "GOSR1", "type": "synonym", "evidence": [ { "id": "NP_001006222", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006222" } ] } ], "protein_names": [ { "name": "Golgi SNAP receptor complex member 1", "type": "recommended", "evidence": [ { "id": "F1NW80", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NW80/entry#names_and_taxonomy" } ] }, { "name": "Golgi SNAP receptor complex member 1", "type": "synonym", "evidence": [ { "id": "NP_001006222", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006222" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: HAEK01046592.1, AJ720233.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000323.1. On Sep 23, 2021 this sequence version replaced NP_001006222.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001006222", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006222" } ] }, { "annotation": "Involved in transport from the ER to the Golgi apparatus as well as in intra-Golgi transport. It belongs to a super-family of proteins called t-SNAREs or soluble NSF (N-ethylmaleimide-sensitive factor) attachment protein receptor. May play a protective role against hydrogen peroxide induced cytotoxicity under glutathione depleted conditions in neuronal cells by regulating the intracellular ROS levels via inhibition of p38 MAPK (MAPK11, MAPK12, MAPK13 and MAPK14). Participates in docking and fusion stage of ER to cis-Golgi transport. Plays an important physiological role in VLDL-transport vesicle-Golgi fusion and thus in VLDL delivery to the hepatic cis-Golgi.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AEV3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEV3#function" }, { "database": "UniProtKB", "id": "ARBA00025091", "url": "https://www.uniprot.org/uniprotkb/ARBA00025091#function" }, { "database": "UniProtKB", "id": "F1NW80", "url": "https://www.uniprot.org/uniprotkb/F1NW80#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NW80", "url": "https://www.uniprot.org/uniprotkb/F1NW80" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "GOSR1", "url": "https://www.uniprot.org/uniprotkb/F1NW80", "locus": { "chromosome": "19", "start_pos": 6778864, "end_pos": 6756351, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029716", "url": "https://www.ensembl.org/id/ENSGALG00010029716" } ] } } ], "crossref": [ { "id": "F1NW80", "url": "https://alphafold.ebi.ac.uk/entry/F1NW80", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000004326", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000004326", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd15864", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15864", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "417591", "url": "https://www.ncbi.nlm.nih.gov/gene/417591", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR023601", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023601", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:417591", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417591", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V1AEV3", "url": "https://www.orthodb.org/?gene=A0A8V1AEV3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NW80", "url": "https://www.orthodb.org/?gene=F1NW80", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21094", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21094", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21094:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21094:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF12352", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12352", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF27017", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF27017", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-6811438", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6811438", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001006222", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006222", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1AEV3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEV3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AEV3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEV3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NW80", "url": "https://www.uniprot.org/uniprotkb/F1NW80", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NW80-1", "url": "https://www.uniprot.org/uniprotkb/F1NW80-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAGSSNYWEDLRKQARQLENELDLKLVSFSKLCTSSRDGRRDSSDTTPLLNGSSQDRMFETMAVEIEQLLGKLTGINDKMAEYTNSAGVPSLNAALMHTLQRHRDILQDYTHEFHKTKANFLAIRERENLLGSVRKDIESYKSGSGVNNRRTELFLKEHEHLRNSDRLIEETISIAMATKENMTSQRGMLKSIQSKMNTLANRFPAVNSLIQRINLRKRRDSFILGSIIGICTILLLLFAFH", "length": 243, "header": "tr|F1NW80-1|F1NW80_CHICK Isoform 1 of Golgi SNAP receptor complex member 1 OS=Gallus gallus OX=9031 GN=GOSR1 PE=1 SV=3 CANONICAL=F1NW80-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AEV3-1", "url": "https://www.uniprot.org/uniprotkb/F1NW80/entry#A0A8V1AEV3-1", "sequence": { "sequence": "MAAGSSNYWEDLRKQARQLENELDLKLVSFSKLCTSSRDGRRDRYSSDTTPLLNGSSQDRMFETMAVEIEQLLGKLTGINDKMAEYTNSAGVPSLNAALMHTLQRHRDILQDYTHEFHKTKANFLAIRERENLLGSVRKDIESYKSGSGVNNRRTELFLKEHEHLRNIAMATKENMTSQRGMLKSIQSKMNTLANRFPAVNSLIQRINLRKRRDSFILGSIIGICTILLLLFAFH", "length": 235, "header": "tr|A0A8V1AEV3-1|F1NW80_CHICK Computationally mapped isoform of Golgi SNAP receptor complex member 1 OS=Gallus gallus OX=9031 GN=GOSR1 PE=1 SV=1 CANONICAL=F1NW80-1" }, "locus": { "chromosome": "19", "start_pos": 6777085, "end_pos": 6756401, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071873.1", "url": "https://www.ensembl.org/id/ENSGALT00010071873.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044563.1", "url": "https://www.ensembl.org/id/ENSGALP00010044563.1" } ] } }, { "isoform_ac": "F1NW80-1", "url": "https://www.uniprot.org/uniprotkb/F1NW80/entry#F1NW80-1", "sequence": { "sequence": "MAAGSSNYWEDLRKQARQLENELDLKLVSFSKLCTSSRDGRRDSSDTTPLLNGSSQDRMFETMAVEIEQLLGKLTGINDKMAEYTNSAGVPSLNAALMHTLQRHRDILQDYTHEFHKTKANFLAIRERENLLGSVRKDIESYKSGSGVNNRRTELFLKEHEHLRNSDRLIEETISIAMATKENMTSQRGMLKSIQSKMNTLANRFPAVNSLIQRINLRKRRDSFILGSIIGICTILLLLFAFH", "length": 243, "header": "tr|F1NW80-1|F1NW80_CHICK Isoform 1 of Golgi SNAP receptor complex member 1 OS=Gallus gallus OX=9031 GN=GOSR1 PE=1 SV=3 CANONICAL=F1NW80-1" }, "locus": { "chromosome": "19", "start_pos": 6777085, "end_pos": 6756401, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071874.1", "url": "https://www.ensembl.org/id/ENSGALT00010071874.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044564.1", "url": "https://www.ensembl.org/id/ENSGALP00010044564.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:417591", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417591", "resource": "KEGG Pathway" }, { "id": "R-GGA-6811438", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6811438", "resource": "Reactome", "description": "Intra-Golgi traffic" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "F1NW80", "url": "https://www.uniprot.org/uniprotkb/F1NW80" } ], "pmid": "" }, { "name": "cis-Golgi network", "id": "GO:0005801", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005801", "evidence": [ { "database": "UniProtKB", "id": "F1NW80", "url": "https://www.uniprot.org/uniprotkb/F1NW80" } ], "pmid": "" }, { "name": "Golgi medial cisterna", "id": "GO:0005797", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005797", "evidence": [ { "database": "UniProtKB", "id": "F1NW80", "url": "https://www.uniprot.org/uniprotkb/F1NW80" } ], "pmid": "" }, { "name": "SNARE complex", "id": "GO:0031201", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031201", "evidence": [ { "database": "UniProtKB", "id": "F1NW80", "url": "https://www.uniprot.org/uniprotkb/F1NW80" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "F1NW80", "url": "https://www.uniprot.org/uniprotkb/F1NW80" } ], "pmid": "" }, { "name": "endoplasmic reticulum to Golgi vesicle-mediated transport", "id": "GO:0006888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006888", "evidence": [ { "database": "UniProtKB", "id": "F1NW80", "url": "https://www.uniprot.org/uniprotkb/F1NW80" } ], "pmid": "" }, { "name": "vesicle fusion", "id": "GO:0006906", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006906", "evidence": [ { "database": "UniProtKB", "id": "F1NW80", "url": "https://www.uniprot.org/uniprotkb/F1NW80" } ], "pmid": "" }, { "name": "inter-Golgi cisterna vesicle-mediated transport", "id": "GO:0048219", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048219", "evidence": [ { "database": "UniProtKB", "id": "F1NW80", "url": "https://www.uniprot.org/uniprotkb/F1NW80" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "SNAP receptor activity", "id": "GO:0005484", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005484", "evidence": [ { "database": "UniProtKB", "id": "F1NW80", "url": "https://www.uniprot.org/uniprotkb/F1NW80" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 183, "end_pos": 185, "annotation": "n_glycosylation_sequon" }, { "start_pos": 52, "end_pos": 54, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1NW80-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 243, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1NW80-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1NW80" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 183, "end_pos": 185 }, { "start_pos": 52, "end_pos": 54 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1NU71-1", "uniprot_ac": "F1NU71", "uniprot_id": "F1NU71_CHICK", "mass": { "chemical_mass": 51265.0, "monoisotopic_mass": 51265.0 }, "refseq": { "ac": "NP_001273092", "name": "mitochondrial import inner membrane translocase subunit TIM44", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001273092" }, "gene_names": [ { "name": "TIMM44", "type": "recommended", "evidence": [ { "id": "F1NU71", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NU71" } ] }, { "name": "TIMM44", "type": "synonym", "evidence": [ { "id": "NP_001273092", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001273092" } ] } ], "protein_names": [ { "name": "Mitochondrial import inner membrane translocase subunit TIM44", "type": "recommended", "evidence": [ { "id": "F1NU71", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NU71/entry#names_and_taxonomy" } ] }, { "name": "mitochondrial import inner membrane translocase subunit TIM44", "type": "synonym", "evidence": [ { "id": "NP_001273092", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001273092" } ] }, { "name": "translocase of inner mitochondrial membrane 44 homolog", "type": "synonym", "evidence": [ { "id": "NP_001273092", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001273092" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: HAEK01017504.1, HAEL01006513.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA103992290, SAMEA103992323 [ECO:0006172] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: inferred from homology ##RefSeq-Attributes-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DT659643.1, CD761016.1, BU108248.1, JAENSK010000374.1, BU402521.1, BU435917.1 and BU354377.1. On Oct 31, 2013 this sequence version replaced XP_418174.2. Sequence Note: This RefSeq record was created from transcript and genomic sequence data from different strains because no single transcript from the same strain was available for the full length of the gene. The extent of this transcript is supported by transcript alignments and orthologous data.", "evidence": [ { "database": "RefSeq", "id": "NP_001273092", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001273092" } ] }, { "annotation": "Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFX8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFX8#function" }, { "database": "UniProtKB", "id": "PIRNR037871", "url": "https://www.uniprot.org/uniprotkb/PIRNR037871#function" }, { "database": "UniProtKB", "id": "F1NU71", "url": "https://www.uniprot.org/uniprotkb/F1NU71#function" }, { "database": "UniProtKB", "id": "ARBA00057148", "url": "https://www.uniprot.org/uniprotkb/ARBA00057148#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NU71", "url": "https://www.uniprot.org/uniprotkb/F1NU71" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TIMM44", "url": "https://www.uniprot.org/uniprotkb/F1NU71", "locus": { "chromosome": "28", "start_pos": 899064, "end_pos": 921555, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010028316", "url": "https://www.ensembl.org/id/ENSGALG00010028316" } ] } } ], "crossref": [ { "id": "F1NU71", "url": "https://alphafold.ebi.ac.uk/entry/F1NU71", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000000352", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000000352", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "420053", "url": "https://www.ncbi.nlm.nih.gov/gene/420053", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR007379", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007379", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017303", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017303", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032710", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032710", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039544", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039544", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:420053", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420053", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "NFQMEPF", "url": "https://omabrowser.org/oma/group/NFQMEPF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AFX8", "url": "https://www.orthodb.org/?gene=A0A8V1AFX8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NU71", "url": "https://www.orthodb.org/?gene=F1NU71", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10721", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10721", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10721:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10721:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04280", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04280", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001273092", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001273092", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1AFX8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFX8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AFX8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFX8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NU71", "url": "https://www.uniprot.org/uniprotkb/F1NU71", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NU71-1", "url": "https://www.uniprot.org/uniprotkb/F1NU71-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAAAASSCRKCLISGMWLMPRRYPVPAVHGGAVYRASRPVSEINQSRCYSSGGRKGFISGFVENIKQELAKNKEMKESIKKFRDEAKKLEESDALREARRKYKTIESETVKTSEVIKKKLEEITGTVKESLDEVSKSDIGRKIKEGVEEAAKTAKQSAESVTKGGEKLGKTAAFKAISQGVETVKKEIDESVLGQTGPYKRPERLRKRTEFSGERIKEERIFEANEEAMGMVLHKDSRWYQQWKDFKDNNVVFNRFFEMKMKYDESDNAFIRASRAVTDKVTDLIGGLFSKTEMSEVLTEILKVDPSFDKDRFLKQCERDIIPNVLEAMISGELDILKDWCYEATYSQLAHPIQQAKAMGLQFHSRILDIDNIDLAMGKMMEQGPVLIITFQAQIVMVIKNQKGEVVEGDPDKVLRMLYVWALCRDQDELNPYAAWRLLDISSSSSEQVL", "length": 451, "header": "tr|F1NU71-1|F1NU71_CHICK Isoform 1 of Mitochondrial import inner membrane translocase subunit TIM44 OS=Gallus gallus OX=9031 GN=TIMM44 PE=1 SV=2 CANONICAL=F1NU71-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AFX8-1", "url": "https://www.uniprot.org/uniprotkb/F1NU71/entry#A0A8V1AFX8-1", "sequence": { "sequence": "MAAAAASSCRKCLISGMWLMPRRYPVPAVHGGAVYRASRPVSEINQSRCYSSGGRKGFISGFVENIKQELAKNKEMKESIKKFRDEAKKLEESDALREARRKYKTIESETVKTSEVIKKKLEEITGTVKESLDEVSKSDIGRKIKEGVEEAAKTAKQSAESVTKGGEKLGKTAAFKAISQGVETVKKEIDESVLGQTGPYKRPERLRKRTEFSGERIKEERIFEANEEAMGMVLHKDSRWYQQWKDFKDNNVVFNRFFEMKMKYDESDNAFIRASRAVTDKVTDLIGGLFSKTEMSEVLTEILKVDPSFDKDRFLKQCERDIIPNVLEAMISGELDILKDWCYEALAMGKMMEQGPVLIITFQAQIVMVIKNQKGEVVEGDPDKVLRMLYVWALCRDQDELNPYAAWRLLDISSSSSEQVL", "length": 421, "header": "tr|A0A8V1AFX8-1|F1NU71_CHICK Computationally mapped isoform of Mitochondrial import inner membrane translocase subunit TIM44 OS=Gallus gallus OX=9031 GN=TIMM44 PE=1 SV=1 CANONICAL=F1NU71-1" }, "locus": { "chromosome": "28", "start_pos": 921526, "end_pos": 901685, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068553.1", "url": "https://www.ensembl.org/id/ENSGALT00010068553.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042161.1", "url": "https://www.ensembl.org/id/ENSGALP00010042161.1" } ] } }, { "isoform_ac": "F1NU71-1", "url": "https://www.uniprot.org/uniprotkb/F1NU71/entry#F1NU71-1", "sequence": { "sequence": "MAAAAASSCRKCLISGMWLMPRRYPVPAVHGGAVYRASRPVSEINQSRCYSSGGRKGFISGFVENIKQELAKNKEMKESIKKFRDEAKKLEESDALREARRKYKTIESETVKTSEVIKKKLEEITGTVKESLDEVSKSDIGRKIKEGVEEAAKTAKQSAESVTKGGEKLGKTAAFKAISQGVETVKKEIDESVLGQTGPYKRPERLRKRTEFSGERIKEERIFEANEEAMGMVLHKDSRWYQQWKDFKDNNVVFNRFFEMKMKYDESDNAFIRASRAVTDKVTDLIGGLFSKTEMSEVLTEILKVDPSFDKDRFLKQCERDIIPNVLEAMISGELDILKDWCYEATYSQLAHPIQQAKAMGLQFHSRILDIDNIDLAMGKMMEQGPVLIITFQAQIVMVIKNQKGEVVEGDPDKVLRMLYVWALCRDQDELNPYAAWRLLDISSSSSEQVL", "length": 451, "header": "tr|F1NU71-1|F1NU71_CHICK Isoform 1 of Mitochondrial import inner membrane translocase subunit TIM44 OS=Gallus gallus OX=9031 GN=TIMM44 PE=1 SV=2 CANONICAL=F1NU71-1" }, "locus": { "chromosome": "28", "start_pos": 921526, "end_pos": 901685, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068550.1", "url": "https://www.ensembl.org/id/ENSGALT00010068550.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042158.1", "url": "https://www.ensembl.org/id/ENSGALP00010042158.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:420053", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420053", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A480JTC0-1", "protein_name": "Mitochondrial import inner membrane translocase subunit TIM44", "gene_name": "TIMM44", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAAAALRGGWCRCPRRCFSSGVHFLSRHNLVPLPLGTYQMPWPSGQQTLSRSYSSGNRKGFLSGLLDNIKQELAKNKEMKESIKKFRDEARKLEESDALQEARRKYRTIESETMRTGEVIRKKLGEITGTVKESLDEVSKSDLGRKIKEGVEEAAKTAKQSAESVSKGGEKLGRTAAFKALSQGVESVKKEIDESVLGQTGPYRRPERLRKRKEFAGEKFKEEKVFEANEEALGVVLHKDSKWYQQWKDFRDNNVVFNRFFEMKMKYDESDNALIRASRVLTDKVTDLLGGLFSKTEMSEVLTEILRVDPAFDKERFLQQCENDIIPNVLEAMISGELDILKDWCYEATYSQLAHPIQQAKALGLQFHSRILDIDNIDLAMGKMMEQGPVLIITFQAQLVMVIKNPKGEVVEGDPDKVLRMLYVWALCRDQDELNPYAAWRLLDISASSTEQVL", "length": 454 }, "evidence": [ { "id": "F1NU71", "url": "https://omabrowser.org/oma/group/F1NU71/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "E1B844-1", "protein_name": "Mitochondrial import inner membrane translocase subunit TIM44", "gene_name": "TIMM44", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAAAALRAGWCRCPRRCVGSGVHLLSSHNLVPLPHGSYQLPRPSGELTLSKSYSSGSRKGFLSGLLDNIKQELAKNKEMKESIKKFRDEAKKLEESDALQEARRKYRTIESETLRTSEVIKKKLGEITGTVKESLDEVSKSDLGRKIKEGVEEAAKTAKQSAESVSKGGERLGRTAAFKALSQGVESVKKEIDESVLGQTGPYRRPERLRKRKEFAGEKFKEEKVFEANEEALGVVLHKDSKWYQQWKDFRDNNVVFNRFFEMKMKYDESDNAFIRASRVLTDKVTDLLGGLFSKTEMSEVLTEILRVDPAFDKDRFLQQCENDIIPNVLEAMISGELDILKDWCYEATYSQLAHPIQQAKALGLQFHSRILDIDHIDLAMGKMMEQGPVLIITFQAQMVMVIKNPKGEVVEGDPDKVLRMLYVWALCRDQDELNPYAAWRLLDISASSTEQGARRCEP", "length": 459 }, "evidence": [ { "id": "F1NU71", "url": "https://omabrowser.org/oma/group/F1NU71/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "O35094-1", "protein_name": "Mitochondrial import inner membrane translocase subunit TIM44", "gene_name": "Timm44", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAAAALRGGWCRCPRRCLGSGIQFLSSHNLPRGGSSYQISRPGGELTLTKSYSSGSRKGFLSGLLDNIKQELAQNKEMKESIKKFRDEAKKLEESDALQEARRKYKTIESETVRTSEAIKKKLGELTGTVKESLDEVSKSDLGRKIKEGVEEAARTAKQSAESVSKGGEKLGKTAAFKAISQGVESVKKEIDESVLGHTGTYRRPERLRKRTEFAGAKFKESKVFEANEEALGVVLHKDSKWYQQWKDFKDNNVVFNRFFEMKMKYDESDNVLIRASRALTDKVTDLLGGLFSKTEMSEVLTEILRVDPTFDKDRFLHQCETDIIPNILEAMISGELDILKDWCYEATYNQLAHSIQQAKALGLQFHSRILDISNVDLAMGKMMEQGPVLIVTFQAQLVMVIKNPKGEVFDGDPDKVLRMLYVWALCRDQEELNPYAAWRLLDISASSTEQIL", "length": 453 }, "evidence": [ { "id": "F1NU71", "url": "https://omabrowser.org/oma/group/F1NU71/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O35857-1", "protein_name": "Mitochondrial import inner membrane translocase subunit TIM44", "gene_name": "Timm44", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAAALRGGWCRCPRRCLGSGIQFLSSHNLPHGSSYQISRPGRELTLTKSYSSGSRKGFLSGLLDNIKQELAKNKEMKESIKKFRDEAKKLEESDALQEARRKYKSIESETVRTSEAIKKKLGELTGTVKESLDEVSKSDLGRKIKEGVEEAARTAKQSAESVSKSGEKLGKTAAFKAISQGVESVKKELDESVLGQTGPYRRPERLRKRTEFAGAKFKESKVFEANEEALGVVLHKDSKWYQQWKDFKDNNVVFNRFFEMKMKYDESDNVLIRASRALTDKVTDLLGGLFSKTEMSEVLTEILRVDPTFDKDHFLHQCETDIIPNILEAMISGELDILKDWCYEATYSQLAHPIQQAKALGFQFHSRILDISNVDLAMGKMMEQGPVLIVTFQAQVVMVIKNSKGEVYDGDPDKVQRMLYVWALCRDQEELNPYAAWRLLDISASSTEQIL", "length": 452 }, "evidence": [ { "id": "F1NU71", "url": "https://omabrowser.org/oma/group/F1NU71/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "O43615-1", "protein_name": "Mitochondrial import inner membrane translocase subunit TIM44", "gene_name": "TIMM44", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAAALRSGWCRCPRRCLGSGIQFLSSHNLPHGSTYQMRRPGGELPLSKSYSSGNRKGFLSGLLDNVKQELAKNKEMKESIKKFRDEARRLEESDVLQEARRKYKTIESETVRTSEVLRKKLGELTGTVKESLHEVSKSDLGRKIKEGVEEAAKTAKQSAESVSKGGEKLGRTAAFRALSQGVESVKKEIDDSVLGQTGPYRRPQRLRKRTEFAGDKFKEEKVFEPNEEALGVVLHKDSKWYQQWKDFKENNVVFNRFFEMKMKYDESDNAFIRASRALTDKVTDLLGGLFSKTEMSEVLTEILRVDPAFDKDRFLKQCENDIIPNVLEAMISGELDILKDWCYEATYSQLAHPIQQAKALGLQFHSRILDIDNVDLAMGKMMEQGPVLIITFQAQLVMVVRNPKGEVVEGDPDKVLRMLYVWALCRDQDELNPYAAWRLLDISASSTEQIL", "length": 452 }, "evidence": [ { "id": "F1NU71", "url": "https://omabrowser.org/oma/group/F1NU71/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q01852-1", "protein_name": "Mitochondrial import inner membrane translocase subunit TIM44", "gene_name": "TIM44", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MHRSTFIRTSGTSSRTLTARYRSQYTGLLVARVLFSTSTTRAQGGNPRSPLQIFRDTFKKEWEKSQELQENIKTLQDASGKLGESEAYKKAREAYLKAQRGSTIVGKTLKKTGETMEHIATKAWESELGKNTRKAAAATAKKLDESFEPVRQTKIYKEVSEVIDDGESSRYGGFITKEQRRLKRERDLASGKRHRAVKSNEDAGTAVVATNIESKESFGKKVEDFKEKTVVGRSIQSLKNKLWDESENPLIVVMRKITNKVGGFFAETESSRVYSQFKLMDPTFSNESFTRHLREYIVPEILEAYVKGDVKVLKKWFSEAPFNVYAAQQKIFKEQDVYADGRILDIRGVEIVSAKLLAPQDIPVLVVGCRAQEINLYRKKKTGEIAAGDEANILMSSYAMVFTRDPEQIDDDETEGWKILEFVRGGSRQFT", "length": 431 }, "evidence": [ { "id": "F1NU71", "url": "https://omabrowser.org/oma/group/F1NU71/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q9VDZ7-1", "protein_name": "Mitochondrial import inner membrane translocase subunit TIM44", "gene_name": "CG117799", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MKATSCRPIPFINFRIVRYFYRPRRLNKYYDIYRIAALVRDRACLFTCQQASQNLQQQQPRFYSAPGRRAGFFSQFFDNMKAEMDKNKEIKDNIRKFREEAQKLEESDALKSARQKFNIVESEAQKSSSMLKEQLGAIKERVGDVLEDASKSHLAKKVTEELSKKARGVSDTISDTSGKLGQTSAFQAISNTTTTIKKEMDSASIENRVYRAPAKLRKRVQLVMSDSDRVVEPNTEATGMELHKDSKFYESWENFKNNNTYVNKVLDWKVKYDESENPVIRASRLLTDKVSDVMGGLFSKTELSETMTELVKIDPSFDQKDFLRDCETDIIPNILESIVRGDLEILKDWCFESTFNIIANPIKEAKKAGVYLDSKILDIENIELAMGKVMEQGPVLIITFQAQQIMCVRDQKSQVVEGDPEKVMRVHYVWVLCRDRNELNPKAAWRLMELSANSSEQFV", "length": 459 }, "evidence": [ { "id": "F1NU71", "url": "https://omabrowser.org/oma/group/F1NU71/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "F1NU71", "url": "https://www.uniprot.org/uniprotkb/F1NU71" } ], "pmid": "" }, { "name": "mitochondrial matrix", "id": "GO:0005759", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005759", "evidence": [ { "database": "UniProtKB", "id": "F1NU71", "url": "https://www.uniprot.org/uniprotkb/F1NU71" } ], "pmid": "" }, { "name": "TIM23 mitochondrial import inner membrane translocase complex", "id": "GO:0005744", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005744", "evidence": [ { "database": "UniProtKB", "id": "F1NU71", "url": "https://www.uniprot.org/uniprotkb/F1NU71" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "protein-folding chaperone binding", "id": "GO:0051087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051087", "evidence": [ { "database": "UniProtKB", "id": "F1NU71", "url": "https://www.uniprot.org/uniprotkb/F1NU71" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "F1NU71", "url": "https://www.uniprot.org/uniprotkb/F1NU71" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "protein import into mitochondrial matrix", "id": "GO:0030150", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030150", "evidence": [ { "database": "UniProtKB", "id": "F1NU71", "url": "https://www.uniprot.org/uniprotkb/F1NU71" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 45, "end_pos": 47, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1NU71-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 451, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1NU71-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1NU71" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1NU71", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NU71" }, { "id": "SM00978", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00978" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Tim44-like", "eco_id": "ECO_0000259", "start_pos": 295, "end_pos": 444, "start_aa": "Met", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 45, "end_pos": 47 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1P220-1", "uniprot_ac": "F1P220", "uniprot_id": "F1P220_CHICK", "mass": { "chemical_mass": 32402.0, "monoisotopic_mass": 32402.0 }, "refseq": { "ac": "XP_414311", "name": "pre-mRNA-splicing factor ISY1 homolog", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_414311" }, "gene_names": [ { "name": "ISY1", "type": "recommended", "evidence": [ { "id": "F1P220", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P220" } ] }, { "name": "ISY1", "type": "synonym", "evidence": [ { "id": "XP_414311", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_414311" } ] } ], "protein_names": [ { "name": "Pre-mRNA-splicing factor ISY1 homolog", "type": "recommended", "evidence": [ { "id": "F1P220", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P220/entry#names_and_taxonomy" } ] }, { "name": "pre-mRNA-splicing factor ISY1 homolog", "type": "synonym", "evidence": [ { "id": "XP_414311", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_414311" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052543.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_414311", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_414311" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1P220", "url": "https://www.uniprot.org/uniprotkb/F1P220" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ISY1", "url": "https://www.uniprot.org/uniprotkb/F1P220", "locus": { "chromosome": "12", "start_pos": 5254646, "end_pos": 5245157, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010027935", "url": "https://www.ensembl.org/id/ENSGALG00010027935" } ] } } ], "crossref": [ { "id": "F1P220", "url": "https://alphafold.ebi.ac.uk/entry/F1P220", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000005012", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000005012", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "415968", "url": "https://www.ncbi.nlm.nih.gov/gene/415968", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR009360", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009360", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029012", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029012", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037200", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037200", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:415968", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:415968", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YHWERRI", "url": "https://omabrowser.org/oma/group/YHWERRI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AIC9", "url": "https://www.orthodb.org/?gene=A0A8V1AIC9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1P220", "url": "https://www.orthodb.org/?gene=F1P220", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13021", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13021", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF06246", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06246", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-6781823", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6781823", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-6782135", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6782135", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-6782210", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6782210", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-72163", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-72163", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_414311", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_414311", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1AIC9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIC9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AIC9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIC9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1P220", "url": "https://www.uniprot.org/uniprotkb/F1P220", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1P220-1", "url": "https://www.uniprot.org/uniprotkb/F1P220-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MARNAEKAMTALARFRQAQLEEGKVKERRPFLASECNELPKAEKWRRQIIGEISKKVAQIQNAGLGEFRIRDLNDEINKLLREKGHWEVRIRELGGPDYARIGPRMLDHEGKEVPGNRGYKYFGAAKDLPGVRELFEKEPLPPPRKTRAELMKSIDAEYYGYRDEDDGILEPLEQEHEKKVIAEAVEKWKMEREARLARGEEEEEEEENIYAVDDESDEEGGKEKEGEDGQQKFIAHVPVPSQQEIEEALVRRKKMELLQKYASETLMAQSEEAKRLLGL", "length": 280, "header": "tr|F1P220-1|F1P220_CHICK Isoform 1 of Pre-mRNA-splicing factor ISY1 homolog OS=Gallus gallus OX=9031 GN=ISY1 PE=1 SV=4 CANONICAL=F1P220-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AIC9-1", "url": "https://www.uniprot.org/uniprotkb/F1P220/entry#A0A8V1AIC9-1", "sequence": { "sequence": "MERRPFLASECNELPKAEKWRRQIIGEISKKVAQIQNAGLGEFRIRDLNDEINKLLREKGHWEVRIRELGGPDYARIGPRMLDHEGKEVPGNRGYKYFGAAKDLPGVRELFEKEPLPPPRKTRAELMKSIDAEYYGYRDEDDGILEPLEQEHEKKVIAEAVEKWKMEREARLARGEEEEEEEENIYAVDDESDEEGGKEKEGEDGQQKFIAHVPVPSQQEIEEALVRRKKMELLQKYASETLMAQSEEAKRLLGL", "length": 255, "header": "tr|A0A8V1AIC9-1|A0A8V1AIC9_CHICK Computationally mapped isoform of Pre-mRNA-splicing factor ISY1 homolog OS=Gallus gallus OX=9031 GN=ISY1 PE=1 SV=1 CANONICAL=F1P220-1" }, "locus": { "chromosome": "12", "start_pos": 5254538, "end_pos": 5245196, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067714.1", "url": "https://www.ensembl.org/id/ENSGALT00010067714.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041457.1", "url": "https://www.ensembl.org/id/ENSGALP00010041457.1" } ] } }, { "isoform_ac": "F1P220-1", "url": "https://www.uniprot.org/uniprotkb/F1P220/entry#F1P220-1", "sequence": { "sequence": "MARNAEKAMTALARFRQAQLEEGKVKERRPFLASECNELPKAEKWRRQIIGEISKKVAQIQNAGLGEFRIRDLNDEINKLLREKGHWEVRIRELGGPDYARIGPRMLDHEGKEVPGNRGYKYFGAAKDLPGVRELFEKEPLPPPRKTRAELMKSIDAEYYGYRDEDDGILEPLEQEHEKKVIAEAVEKWKMEREARLARGEEEEEEEENIYAVDDESDEEGGKEKEGEDGQQKFIAHVPVPSQQEIEEALVRRKKMELLQKYASETLMAQSEEAKRLLGL", "length": 280, "header": "tr|F1P220-1|F1P220_CHICK Isoform 1 of Pre-mRNA-splicing factor ISY1 homolog OS=Gallus gallus OX=9031 GN=ISY1 PE=1 SV=4 CANONICAL=F1P220-1" }, "locus": { "chromosome": "12", "start_pos": 5254538, "end_pos": 5245196, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067712.1", "url": "https://www.ensembl.org/id/ENSGALT00010067712.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041455.1", "url": "https://www.ensembl.org/id/ENSGALP00010041455.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:415968", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:415968", "resource": "KEGG Pathway" }, { "id": "R-GGA-6781823", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6781823", "resource": "Reactome", "description": "Formation of TC-NER Pre-Incision Complex" }, { "id": "R-GGA-6782135", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6782135", "resource": "Reactome", "description": "Dual incision in TC-NER" }, { "id": "R-GGA-6782210", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6782210", "resource": "Reactome", "description": "Gap-filling DNA repair synthesis and ligation in TC-NER" }, { "id": "R-GGA-72163", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-72163", "resource": "Reactome", "description": "mRNA Splicing - Major Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "G3HID7-1", "protein_name": "Pre-mRNA-splicing factor ISY1 homolog", "gene_name": "Isy1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MARNAEKAMTALARFRQAQLEEGKVKERRPFLASECTELPKAEKWRRQIIGEISKKVAQIQNAGLGEFRIRDLNDEINKLLREKGHWEVRIKELGGPDYGKVGPKMLDHEGKEVPGNRGYKYFGAAKDLPGVRELFEKEPLPPPRKTRAELMKAIDFEYYGYLDEDDGVIVPLEQDYEKKLRAELVGKWKAEREARLARGEKEEEEEEEEEVNIYAVTEEESDEEGSQEKAGEDGQQKFIAHVPVPSQQEIEEALVRRKKMELLQKYASETLQAQSEEAKRLLGY", "length": 285 }, "evidence": [ { "id": "F1P220", "url": "https://omabrowser.org/oma/group/F1P220/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q53B90-1", "protein_name": "Ras-related protein Rab-43", "gene_name": "Rab43", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAGPGPGDQDEHYDFLFKLVLVGDASVGKTCVVQRFKTGAFSARQGSTIGVDFTMKTLEIQGKRVKLQIWDTAGQERFRTITQSYYRSANGAILAYDISKRSTFLSVPHWIEDVRKYAGSNIVQLLIGNKSDLADLREVPLAEAQSLAEHYDILCAIETSAKDSSNVEEAFTRVATELIMRHGGPMFSEKNTDHIQLDSKDIAESWGCGC", "length": 210 }, "evidence": [ { "id": "F1P220", "url": "https://omabrowser.org/oma/group/F1P220/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6AYB3-1", "protein_name": "Pre-mRNA-splicing factor ISY1 homolog", "gene_name": "Isy1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MARNAEKAMTALARFRQAQLEEGKVKERRPFLASECTELPKAEKWRRQIIGEISKKVAQIQNAGLGEFRIRDLNDEINKLLREKGHWEVRIKELGGPDYGKVGPKMLDHEGKEVPGNRGYKYFGAAKDLPGVRELFEKEPLPPPRKTRAELMKAIDFEYYGYLDEDDGVIVPLEQEYEKRLRAELVEKWKAEREARLARGEKEEEEEEEEINIYAVTEEESDEEGSQEKAGEDGQQKFIAHVPVPSQQEIEEALVRRKKMELLQKYASETLQAQSEEAKRLLGY", "length": 284 }, "evidence": [ { "id": "F1P220", "url": "https://omabrowser.org/oma/group/F1P220/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9LS97-1", "protein_name": "Pre-mRNA-splicing factor ISY1-like protein", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MARNEEKAQSMLNRFITQKESEKKKPKERRPYLASECRDLAEADKWRQQILREIGSKVAEIQNEGLGEHRLRDLNDEINKLLRERYHWERRIVELGGHNYSKHSAKMTDLEGNIIDVPNPSGRGPGYRYFGAAKKLPGVRELFEKPPELRKRKTRYDIYKRIDASYYGYRDDEDGILEKLERKSEGGMRKRSVEEWRRLDEVRKEARKGASEVVSVGAAAAAAREVLFEEEEDVVEEERMEREKEEEKEREFVVHVPLPDEKEIEKMVLEKKKMDLLSKYASEDLVEQQTEAKSMLNIHR", "length": 300 }, "evidence": [ { "id": "F1P220", "url": "https://omabrowser.org/oma/group/F1P220/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9ULR0-3", "protein_name": "Pre-mRNA-splicing factor ISY1 homolog", "gene_name": "ISY1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MARNAEKAMTALARFRQAQLEEGKVKERRPFLASECTELPKAEKWRRQIIGEISKKVAQIQNAGLGEFRIRDLNDEINKLLREKGHWEVRIKELGGPDYGKVGPKMLDHEGKEVPGNRGYKYFGAAKDLPGVRELFEKEPLPPPRKTRAELMKAIDFEYYGYLDEDDGVIVPLEQEYEKKLRAELVEKWKAEREARLARGEKEEEEEEEEEINIYAVTEEESDEEGSQEKGGDDSQQKFIAHVPVPSQQEIEEALVRRKKMELLQKYASETLQAQSEEARRLLGY", "length": 285 }, "evidence": [ { "id": "F1P220", "url": "https://omabrowser.org/oma/group/F1P220/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VHV6-1", "protein_name": "Pre-mRNA-splicing factor ISY1 homolog", "gene_name": "Dmel\\CG9667", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MARNAEKAMTTLARWRAAKEVESGEKERRPYLASECHDLPRCEKFRLEIIRDISKKVAQIQNAGLGEFRIRDLNDEINKLLREKRHWENQISSLGGPHYRRYGPKMFDAEGREVPGNRGYKYFGAAKDLPGVRELFEQDPPPPPRKSRAELMKDIDAEYYGYRDDEDGVLIPLEERIERAAIQKAVQEWREKMARDGRIIDDEEEDEIYPLSGPAREAIEDAKARAAVEDPHGLLASKFTAHVPVPTQQDVQEALLRQRKRELLEKYAGGTN", "length": 272 }, "evidence": [ { "id": "F1P220", "url": "https://omabrowser.org/oma/group/F1P220/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 7, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1P220", "url": "https://www.uniprot.org/uniprotkb/F1P220" } ], "pmid": "" }, { "name": "nuclear speck", "id": "GO:0016607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016607", "evidence": [ { "database": "UniProtKB", "id": "F1P220", "url": "https://www.uniprot.org/uniprotkb/F1P220" } ], "pmid": "" }, { "name": "catalytic step 2 spliceosome", "id": "GO:0071013", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071013", "evidence": [ { "database": "UniProtKB", "id": "F1P220", "url": "https://www.uniprot.org/uniprotkb/F1P220" } ], "pmid": "" }, { "name": "post-mRNA release spliceosomal complex", "id": "GO:0071014", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071014", "evidence": [ { "database": "UniProtKB", "id": "F1P220", "url": "https://www.uniprot.org/uniprotkb/F1P220" } ], "pmid": "" }, { "name": "U2-type catalytic step 1 spliceosome", "id": "GO:0071006", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071006", "evidence": [ { "database": "UniProtKB", "id": "F1P220", "url": "https://www.uniprot.org/uniprotkb/F1P220" } ], "pmid": "" }, { "name": "Prp19 complex", "id": "GO:0000974", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000974", "evidence": [ { "database": "UniProtKB", "id": "F1P220", "url": "https://www.uniprot.org/uniprotkb/F1P220" } ], "pmid": "" }, { "name": "post-spliceosomal complex", "id": "GO:0071020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071020", "evidence": [ { "database": "UniProtKB", "id": "F1P220", "url": "https://www.uniprot.org/uniprotkb/F1P220" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "generation of catalytic spliceosome for second transesterification step", "id": "GO:0000350", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000350", "evidence": [ { "database": "UniProtKB", "id": "F1P220", "url": "https://www.uniprot.org/uniprotkb/F1P220" } ], "pmid": "" }, { "name": "mRNA 3'-splice site recognition", "id": "GO:0000389", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000389", "evidence": [ { "database": "UniProtKB", "id": "F1P220", "url": "https://www.uniprot.org/uniprotkb/F1P220" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1P220-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 280, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1P220-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1P220" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1NHV9-1", "uniprot_ac": "F1NHV9", "uniprot_id": "F1NHV9_CHICK", "mass": { "chemical_mass": 24643.0, "monoisotopic_mass": 24643.0 }, "refseq": { "ac": "XP_418224", "name": "DNA-directed RNA polymerases I, II, and III subunit RPABC1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_418224" }, "gene_names": [ { "name": "POLR2E", "type": "recommended", "evidence": [ { "id": "F1NHV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NHV9" } ] }, { "name": "POLR2E", "type": "synonym", "evidence": [ { "id": "XP_418224", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_418224" } ] } ], "protein_names": [ { "name": "DNA-directed RNA polymerases I, II, and III subunit RPABC1", "type": "recommended", "evidence": [ { "id": "F1NHV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NHV9/entry#names_and_taxonomy" } ] }, { "name": "DNA-directed RNA polymerase II subunit E", "type": "synonym", "evidence": [ { "id": "F1NHV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NHV9/entry#names_and_taxonomy" } ] }, { "name": "DNA-directed RNA polymerases I, II, and III subunit RPABC1", "type": "synonym", "evidence": [ { "id": "XP_418224", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_418224" } ] }, { "name": "RPB5 homolog", "type": "synonym", "evidence": [ { "id": "F1NHV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NHV9/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052559.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Nov 16, 2006 this sequence version replaced XP_418224.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_418224", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_418224" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NHV9", "url": "https://www.uniprot.org/uniprotkb/F1NHV9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "POLR2E", "url": "https://www.uniprot.org/uniprotkb/F1NHV9", "locus": { "chromosome": "28", "start_pos": 3367337, "end_pos": 3370471, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010027995", "url": "https://www.ensembl.org/id/ENSGALG00010027995" } ] } } ], "crossref": [ { "id": "F1NHV9", "url": "https://alphafold.ebi.ac.uk/entry/F1NHV9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000002591", "url": 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"evidence": [ { "database": "UniProtKB", "id": "F1NHV9", "url": "https://www.uniprot.org/uniprotkb/F1NHV9" } ], "pmid": "" }, { "name": "transcription initiation at RNA polymerase III promoter", "id": "GO:0006384", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006384", "evidence": [ { "database": "UniProtKB", "id": "F1NHV9", "url": "https://www.uniprot.org/uniprotkb/F1NHV9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 138, "end_pos": 140, "annotation": "n_glycosylation_sequon" }, { "start_pos": 98, "end_pos": 100, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1NHV9-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 210, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1NHV9-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1NHV9" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1NHV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NHV9" }, { "id": "PF03871", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03871" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RNA polymerase Rpb5 N-terminal", "eco_id": "ECO_0000259", "start_pos": 4, "end_pos": 94, "start_aa": "Glu", "end_aa": "Met", "glycosite_overlap": "" }, { "evidence": [ { "id": "F1NHV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NHV9" }, { "id": "PF01191", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01191" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RNA polymerase subunit H/Rpb5 C-terminal", "eco_id": "ECO_0000259", "start_pos": 137, "end_pos": 209, "start_aa": "Ile", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 138, "end_pos": 140 }, { "start_pos": 98, "end_pos": 100 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1NQY0-1", "uniprot_ac": "F1NQY0", "uniprot_id": "F1NQY0_CHICK", "mass": { "chemical_mass": 61142.0, "monoisotopic_mass": 61142.0 }, "refseq": { "ac": "NP_001032916", "name": "vascular endothelial zinc finger 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001032916" }, "gene_names": [ { "name": "VEZF1", "type": "recommended", "evidence": [ { "id": "F1NQY0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NQY0" } ] }, { "name": "BGP1", "type": "synonym", "evidence": [ { "id": "NP_001032916", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001032916" } ] }, { "name": "VEZF1", "type": "synonym", "evidence": [ { "id": "NP_001032916", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001032916" } ] } ], "protein_names": [ { "name": "Vascular endothelial zinc finger 1", "type": "synonym", "evidence": [ { "id": "F1NQY0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NQY0/entry#names_and_taxonomy" } ] }, { "name": "beta globin protein 1", "type": "synonym", "evidence": [ { "id": "NP_001032916", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001032916" } ] }, { "name": "vascular endothelial zinc finger 1", "type": "synonym", "evidence": [ { "id": "NP_001032916", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001032916" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AY775302.1, SRR13267659.57764.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000323.1. On Sep 23, 2021 this sequence version replaced NP_001032916.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001032916", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001032916" } ] }, { "annotation": "VEZF1 are sufficient to mediate demethylation and protection of the CpG island promoter from DNA methylation.", "evidence": [ { "database": "RefSeq", "id": "NP_001032916", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001032916" }, { "database": "PubMed", "id": "20062523", "url": "https://glygen.org/publication/PubMed/20062523" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NQY0", "url": "https://www.uniprot.org/uniprotkb/F1NQY0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "VEZF1", "url": "https://www.uniprot.org/uniprotkb/F1NQY0", "locus": { "chromosome": "19", "start_pos": 9217036, "end_pos": 9204036, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029505", "url": "https://www.ensembl.org/id/ENSGALG00010029505" } ] } } ], "crossref": [ { "id": "F1NQY0", "url": "https://alphafold.ebi.ac.uk/entry/F1NQY0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000005530", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000005530", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "417664", "url": "https://www.ncbi.nlm.nih.gov/gene/417664", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050331", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050331", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:417664", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417664", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V1AKI6", "url": "https://www.orthodb.org/?gene=A0A8V1AKI6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AMF6", "url": "https://www.orthodb.org/?gene=A0A8V1AMF6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NQY0", "url": "https://www.orthodb.org/?gene=F1NQY0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16515", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16515", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16515:SF19", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16515:SF19", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16515:SF49", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16515:SF49", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24393", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24393", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24393:SF15", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24393:SF15", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13894", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13894", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001032916", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001032916", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1AKI6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKI6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AKI6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKI6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AMF6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMF6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AMF6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMF6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NQY0", "url": "https://www.uniprot.org/uniprotkb/F1NQY0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NQY0-1", "url": "https://www.uniprot.org/uniprotkb/F1NQY0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEANWTAFLFQAHEASHHQQQAAPNSLLPLLSSAVEPPDQKPILPLPITQKPQPAPETLKDAIVGIKKEKPKTSFVCTYCSKAFRDSYHLRRHESCHTGIKLVSRPKKTPTTMVPLISTIAGDNSRSSLVSTIAGILSTVTTSSSATNPSSSAGATAMAVTQTVKKPSKPVKKNHACEMCGKAFRDVYHLNRHKLSHSDEKPFECPICNQRFKRKDRMTYHVRSHEGGITKPYTCGVCGKGFSRPDHLSCHVKHVHSTERPFKCQTCTAAFATKDRLRTHMVRHEGKVSCNICGKLLSAAYITSHLKTHGQSQSINCNTCKQGINKTCMSEETSNQKQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHVTSWPGKQVETLRLWEEAVKARKKECQFTFEKAIEYVPFEAANLCQTSTAATTPVTLTTPFNITSSVASGTITNPVTVAAAMSMRSPVNVSSAVNISSPMNLGHPVTITSPLSMTSPLTLTTPVNLPTPVTAPVNIAHPVTITSPMNLPTPMTLAGPLNIAMRPVESMPFLPQALPTSPPW", "length": 555, "header": "tr|F1NQY0-1|F1NQY0_CHICK Isoform 1 of Vascular endothelial zinc finger 1 OS=Gallus gallus OX=9031 GN=VEZF1 PE=3 SV=3 CANONICAL=F1NQY0-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AKI6-1", "url": "https://www.uniprot.org/uniprotkb/F1NQY0/entry#A0A8V1AKI6-1", "sequence": { "sequence": "MEANWTAFLFQAHEASHHQQQAAPNSLLPLLSSAVEPPDQKPILPLPITQKPQPAPETLKDAIVGIKKEKPKTSFVCTYCSKAFRDSYHLRRHESCHTGIKLVSRPKKTPTTMVPLISTIAGDNSRSSLVSTIAGILSTVTTSSSATNPSSSAGATAMAVTQTVKKPSKPVKKNHACEMCGKAFRDVYHLNRHKLSHSDEKPFECPICNQRFKRKDRMTYHVRSHEGGITKPYTCGVCGKGFSRPDHLSCHVKHVHSTERPFKCQTCTAAFATKDRLRTHMVRHEGKVSCNICGKLLSAAYITSHLKTHGQSQSINCNTCKQGINKTCMSEETSNQKQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHVTSWPGKQVETLRLWEEAVKARKKEAANLCQTSTAATTPVTLTTPFNITSSVASGTITNPVTVAAAMSMRSPVNVSSAVNISSPMNLGHPVTITSPLSMTSPLTLTTPVNLPTPVTAPVNIAHPVTITSPMNLPTPMTLAGPLNIAMRPVESMPFLPQALPTSPPW", "length": 540, "header": "tr|A0A8V1AKI6-1|A0A8V1AKI6_CHICK Computationally mapped isoform of Vascular endothelial zinc finger 1 OS=Gallus gallus OX=9031 GN=VEZF1 PE=4 SV=1 CANONICAL=F1NQY0-1" }, "locus": { "chromosome": "19", "start_pos": 9215009, "end_pos": 9204205, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071327.1", "url": "https://www.ensembl.org/id/ENSGALT00010071327.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044018.1", "url": "https://www.ensembl.org/id/ENSGALP00010044018.1" } ] } }, { "isoform_ac": "A0A8V1AMF6-1", "url": "https://www.uniprot.org/uniprotkb/F1NQY0/entry#A0A8V1AMF6-1", "sequence": { "sequence": "AAPGWVALVAAHEASHHQQQAAPNSLLPLLSSAVEPPDQKPILPLPITQKPQPAPETLKDAIVGIKKEKPKTSFVCTYCSKAFRDSYHLRRHESCHTGIKLVSRPKKTPTTMVPLISTIAGDNSRSSLVSTIAGILSTVTTSSSATNPSSSAGATAMAVTQTVKKPSKPVKKNHACEMCGKAFRDVYHLNRHKLSHSDEKPFECPICNQRFKRKDRMTYHVRSHEGGITKPYTCGVCGKGFSRPDHLSCHVKHVHSTERPFKCQTCTAAFATKDRLRTHMVRHEGKVSCNICGKLLSAAYITSHLKTHGQSQSINCNTCKQGINKTCMSEETSNQKQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHVTSWPGKQVETLRLWEEAVKARKKECQFTFEKAIEYVPFEAANLCQTSTAATTPVTLTTPFNITSSVASGTITNPVTVAAAMSMRSPVNVSSAVNISSPMNLGHPVTITSPLSMTSPLTLTTPVNLPTPVTAPVNIAHPVTITSPMNLPTPMTLAGPLNIAMRPVESMPFLPQALPTSPPW", "length": 554, "header": "tr|A0A8V1AMF6-1|A0A8V1AMF6_CHICK Computationally mapped isoform of Vascular endothelial zinc finger 1 OS=Gallus gallus OX=9031 GN=VEZF1 PE=4 SV=1 CANONICAL=F1NQY0-1" }, "locus": { "chromosome": "19", "start_pos": 9215009, "end_pos": 9208042, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071326.1", "url": "https://www.ensembl.org/id/ENSGALT00010071326.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044017.1", "url": "https://www.ensembl.org/id/ENSGALP00010044017.1" } ] } }, { "isoform_ac": "F1NQY0-1", "url": "https://www.uniprot.org/uniprotkb/F1NQY0/entry#F1NQY0-1", "sequence": { "sequence": "MEANWTAFLFQAHEASHHQQQAAPNSLLPLLSSAVEPPDQKPILPLPITQKPQPAPETLKDAIVGIKKEKPKTSFVCTYCSKAFRDSYHLRRHESCHTGIKLVSRPKKTPTTMVPLISTIAGDNSRSSLVSTIAGILSTVTTSSSATNPSSSAGATAMAVTQTVKKPSKPVKKNHACEMCGKAFRDVYHLNRHKLSHSDEKPFECPICNQRFKRKDRMTYHVRSHEGGITKPYTCGVCGKGFSRPDHLSCHVKHVHSTERPFKCQTCTAAFATKDRLRTHMVRHEGKVSCNICGKLLSAAYITSHLKTHGQSQSINCNTCKQGINKTCMSEETSNQKQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHVTSWPGKQVETLRLWEEAVKARKKECQFTFEKAIEYVPFEAANLCQTSTAATTPVTLTTPFNITSSVASGTITNPVTVAAAMSMRSPVNVSSAVNISSPMNLGHPVTITSPLSMTSPLTLTTPVNLPTPVTAPVNIAHPVTITSPMNLPTPMTLAGPLNIAMRPVESMPFLPQALPTSPPW", "length": 555, "header": "tr|F1NQY0-1|F1NQY0_CHICK Isoform 1 of Vascular endothelial zinc finger 1 OS=Gallus gallus OX=9031 GN=VEZF1 PE=3 SV=3 CANONICAL=F1NQY0-1" }, "locus": { "chromosome": "19", "start_pos": 9215009, "end_pos": 9204205, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071328.1", "url": "https://www.ensembl.org/id/ENSGALT00010071328.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044019.1", "url": "https://www.ensembl.org/id/ENSGALP00010044019.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "VEZF1 elements mediate protection from DNA methylation.", "journal": "PLoS genetics", "date": "2010-01", "authors": "Dickson Jacqueline, Gowher Humaira, Strogantsev Ruslan, Gaszner Miklos, Hair Alan, Felsenfeld Gary, West Adam G", "evidence": [ { "database": "RefSeq", "id": "NP_001032916", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001032916" } ], "reference": [ { "type": "PubMed", "id": "20062523", "url": "https://glygen.org/publication/PubMed/20062523" } ] } ], "pathway": [ { "id": "gga:417664", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417664", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1NQY0", "url": "https://www.uniprot.org/uniprotkb/F1NQY0" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "F1NQY0", "url": "https://www.uniprot.org/uniprotkb/F1NQY0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "F1NQY0", "url": "https://www.uniprot.org/uniprotkb/F1NQY0" } ], "pmid": "" }, { "name": "positive regulation of DNA-templated transcription", "id": "GO:0045893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045893", "evidence": [ { "database": "UniProtKB", "id": "F1NQY0", "url": "https://www.uniprot.org/uniprotkb/F1NQY0" } ], "pmid": "" }, { "name": "regulation of 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eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052539.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_004943147.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004943147", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004943147" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCV2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCV2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "GPSM2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCV2", "locus": {} } ], "crossref": [ { "id": "A0A8V0YCV2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YCV2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000002090", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000002090", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "424342", "url": "https://www.ncbi.nlm.nih.gov/gene/424342", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003109", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003109", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011990", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011990", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019734", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019734", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052386", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052386", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:424342", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424342", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "NQSVLGH", "url": "https://omabrowser.org/oma/group/NQSVLGH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YCV2", "url": "https://www.orthodb.org/?gene=A0A8V0YCV2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1BR28", "url": "https://www.orthodb.org/?gene=E1BR28", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45954", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45954", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45954:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45954:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02188", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02188", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13176", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13176", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13374", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13374", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13424", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13424", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-418594", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-418594", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_004943147", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004943147", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YCV2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCV2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YCV2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCV2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BR28", "url": "https://www.uniprot.org/uniprotkb/E1BR28", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BR28-1", "url": "https://www.uniprot.org/uniprotkb/E1BR28-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MHFFRTRDNWTKYCIQSDRYLFLLNLCRMEASCLELALEGERLCKAGDCRAGVSFFEAAVQVGTEDLKTLSAIYSQLGNAYFYLHEYAKALEYHHHDLTLARTIGDLVGEAKASGNLGNTLKVLGNFEEAIVCCQRHLDISRELNDKVGEARALYNLGNVYHSKGKNVACAGTHDPGELPEDVKNALQKAANYYEENLTIVTELGDRAAQGRAFGNLGNTHYLLGNFRSAVLAHEQRLLIAKEFGDRSAERRAYSNLGNAYIFLGEFETASEYYKRTLQLARQLKDRAVEAQACYSLGNTYTLLQDYEKAIDYHLKHLVIAQELNDKIGEGRACWSLGNAYTALGNHDQAMHFAERHLEISREVGDRSGELTARLNLSDLQMVLGLSYSTNTSMMSESHAVDNSLNGTRPRVGRRHSMENMELMKLTPEKVQSWNSEILAKQKPLIAKPSAKLHFVNRLKGKKYKNGTASKVLQDASNSIDSRLPSAQRRNSRETVADEGFFDLLSRFQSNRMDDQRCHFQEKNRFSAASVATSSTPPKTIQKSFSASVVSPHTDEFLDLLASSQSRRLDDQRASFSNLPGLRLNHRTSPSVLGHLMASNNRELDEDFFDILIKCQGSRLDDQRCAPPSSAKGPTVPDEDFFSLIVRSQAKRMDEQRVHLPSAIKGPSSS", "length": 670, "header": "tr|A0A8V0YCV2-1|A0A8V0YCV2_CHICK Isoform 1 of G protein signaling modulator 2 OS=Gallus gallus OX=9031 GN=GPSM2 PE=3 SV=1 CANONICAL=A0A8V0YCV2-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YCV2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCV2/entry#A0A8V0YCV2-1", "sequence": { "sequence": "MHFFRTRDNWTKYCIQSDRYLFLLNLCRMEASCLELALEGERLCKAGDCRAGVSFFEAAVQVGTEDLKTLSAIYSQLGNAYFYLHEYAKALEYHHHDLTLARTIGDLVGEAKASGNLGNTLKVLGNFEEAIVCCQRHLDISRELNDKVGEARALYNLGNVYHSKGKNVACAGTHDPGELPEDVKNALQKAANYYEENLTIVTELGDRAAQGRAFGNLGNTHYLLGNFRSAVLAHEQRLLIAKEFGDRSAERRAYSNLGNAYIFLGEFETASEYYKRTLQLARQLKDRAVEAQACYSLGNTYTLLQDYEKAIDYHLKHLVIAQELNDKIGEGRACWSLGNAYTALGNHDQAMHFAERHLEISREVGDRSGELTARLNLSDLQMVLGLSYSTNTSMMSESHAVDNSLNGTRPRVGRRHSMENMELMKLTPEKVQSWNSEILAKQKPLIAKPSAKLHFVNRLKGKKYKNGTASKVLQDASNSIDSRLPSAQRRNSRETVADEGFFDLLSRFQSNRMDDQRCHFQEKNRFSAASVATSSTPPKTIQKSFSASVVSPHTDEFLDLLASSQSRRLDDQRASFSNLPGLRLNHRTSPSVLGHLMASNNRELDEDFFDILIKCQGSRLDDQRCAPPSSAKGPTVPDEDFFSLIVRSQAKRMDEQRVHLPSAIKGPSSS", "length": 670, "header": "tr|A0A8V0YCV2-1|A0A8V0YCV2_CHICK Isoform 1 of G protein signaling modulator 2 OS=Gallus gallus OX=9031 GN=GPSM2 PE=3 SV=1 CANONICAL=A0A8V0YCV2-1" }, "locus": { "chromosome": "8", "start_pos": 1344473, "end_pos": 1333760, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029002.1", "url": "https://www.ensembl.org/id/ENSGALT00010029002.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016761.1", "url": "https://www.ensembl.org/id/ENSGALP00010016761.1" } ] } }, { "isoform_ac": "E1BR28-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCV2/entry#E1BR28-1", "sequence": { "sequence": "MEESNVLISMREDQSFHVRYRMEASCLELALEGERLCKAGDCRAGVSFFEAAVQVGTEDLKTLSAIYSQLGNAYFYLHEYAKALEYHHHDLTLARTIGDLVGEAKASGNLGNTLKVLGNFEEAIVCCQRHLDISRELNDKVGEARALYNLGNVYHSKGKNVACAGTHDPGELPEDVKNALQKAANYYEENLTIVTELGDRAAQGRAFGNLGNTHYLLGNFRSAVLAHEQRLLIAKEFGDRSAERRAYSNLGNAYIFLGEFETASEYYKRTLQLARQLKDRAVEAQACYSLGNTYTLLQDYEKAIDYHLKHLVIAQELNDKIGEGRACWSLGNAYTALGNHDQAMHFAERHLEISREVGDRSGELTARLNLSDLQMVLGLSYSTNTSMMSESHAVDNSLNGTRPRVGRRHSMENMELMKLTPEKVQSWNSEILAKQKPLIAKPSAKLHFVNRLKGKKYKNGTASKVLQDASNSIDSRLPSAQRRNSRETVADEGFFDLLSRFQSNRMDDQRCHFQEKNRFSAASVATSSTPPKTIQKSFSASVVSPHTDEFLDLLASSQSRRLDDQRASFSNLPGLRLNHRTSPSVLGHLMASNNRELDEDFFDILIKCQGSRLDDQRCAPPSSAKGPTVPDEDFFSLIVRSQAKRMDEQRVHLPSAIKGPSSS", "length": 663, "header": "tr|E1BR28-1|A0A8V0YCV2_CHICK Computationally mapped isoform of G protein signaling modulator 2 OS=Gallus gallus OX=9031 GN=GPSM2 PE=3 SV=3 CANONICAL=A0A8V0YCV2-1" }, "locus": { "chromosome": "8", "start_pos": 1344473, "end_pos": 1327925, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029004.1", "url": "https://www.ensembl.org/id/ENSGALT00010029004.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016763.1", "url": "https://www.ensembl.org/id/ENSGALP00010016763.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 635, "start_aa": "Thr", "end_pos": 635, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr635", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:424342", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424342", "resource": "KEGG Pathway" }, { "id": "R-GGA-418594", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-418594", "resource": "Reactome", "description": "G alpha (i) signalling events" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6AGM3-1", "protein_name": "G-protein signaling modulator 2", "gene_name": "Gpsm2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLPTLLSYTPSLSLRLFLRMEASCLELALEGERLCKSGDCRAGVSFFEAAVQVGTEDLKTLSAIYSQLGNAYFYLHDYAKALEYHHHDLTLARTIGDQLGEAKASGNLGNTLKVLGNFDEAIVCCQRHLDISRELNDKVGEARALYNLGNVYHAKGKSFGCPGPQDVGEFPEEVRLALQAAVELYEENLSLVTALGDRAAQGRAFGNLGNTHYLLGNFRDAVIAHEQRLLIAKEFGDKAAERRAYSNLGNAYIFLGEFETASEYYRKTLLLARQLKDRAVEAQSCYSLGNTYTLLQDYEKAIEYHLKHLAIAQELKDRIGEGRACWSLGNAYTALGNHDQAMHFAEKHLEISREVGDKSGELTARLNLSDLQMVLGLSYSTNNSMMSENIEIDGSLHGAGTKLGRRHSMENMELMKLTPEKVPNWNSEILAKQKPCIAKSSAKLLFVNRLKGKKSKSGSASTKALHHASNPIDHRAPHAQKKVGSDAVGDEGFFDLLRRLQSSRMEDQRCHLQENRTASVAASSATPKMVKAPSASVVSPNTDEFLDLLASSQSRRLDDQRASFSNLPGLRLTEGNNQSVLERLMTNDKKEPDEDFFDILVKCQGSRLDDQRCAPPPAATKGPTVPDEDFFSLILRSQAKRMDEQRVLLQRDPNRDSEFGLKELLQNNALLEFKHSGK", "length": 678 }, "evidence": [ { "id": "A0A8V0YCV2", "url": "https://omabrowser.org/oma/group/A0A8V0YCV2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A9J7JBF3-1", "protein_name": "G-protein-signaling modulator 1", "gene_name": "Gpsm2", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MGEPGAGRRRRGAQALRDPGWRWDTERPAGESEALAHVTSRGRALGARAGLPRCPCEARRRGGDRPAGSAVVSSLRPEALTPAAPSRSQEPLAGGRMEASCLELALEGERLCKSGDCRAGVSFFEAAVQVGTEDLKTLSAIYSQLGNAYFYLHDYAKALEYHHHDLTLARTIGDQLGEAKASGNLGNTLKVLGNFDEAIVCCQRHLDISRELNDKVGEARALYNLGNVYHAKGKSFGCPGPQDVGEFPEEVRNALQAAVDLYEENLSLVTALGDRAAQGRAFGNLGNTHYLLGNFRDAVIAHEQRLLIAKEFGDKAAERRAYSNLGNAYIFLGEFETASEYYRKTLLLARQLKDRAVEAQSCYSLGNTYTLLQDYEKAIDYHLKHLAIAQELKDRIGEGRACWSLGNAYTALGNHDQAMHFAEKHLEISREVGDKSGELTARLNLSDLQMVLGLSYSTNNSMMSENIELDGSLHGARSKLGRRHSMENMELMKLTPEKVPNWNSEILAKQKPLIAKPSAKLLFVNRLKGKKYKSSSTTKVLHDASNSIDHHAPNPQKKTSAETIGDEGFFDLLRRFQSNRMDDQRCYLQENCRTSSTAASSTTPKMMKAPSVPVVSPNTDEFLDLLASSQSRRLDDQRASFSNLPGLRLTKNNNQSVLEHLMTNDKKEPDEDFFDILVKCQGSRLDDQRCAPPPATTKGPTVPDEDFFSLILRSQAKRMDEQRVLLQRDPNRDTELGLKELLQNNALLEFKHSGK", "length": 755 }, "evidence": [ { "id": "A0A8V0YCV2", "url": "https://omabrowser.org/oma/group/A0A8V0YCV2/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "E1BIX7-1", "protein_name": "G protein signaling modulator 2", "gene_name": "GPSM2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MEENLINMREDHSFHVRYRMEASCLELALEGERLCKSGDCRAGVSFFEAAVQVGTEDLKTLSAIYSQLGNAYFYLHDYAKALEYHHHDLTLARTIGDQLGEAKASGNLGNTLKVLGNFDEAIVCCQRHLDISRELNDKVGEARALYNLGNVYHAKGKSFGCPGPQEVGEFPEEVRNALQAAVDYYEENLSLVTALGDRAAQGRAFGNLGNTHYLLGNFRDAVIAHEQRLLIAKEFGDKAAERRAYSNLGNAYIFLGEFETASEYYKKTLLLARQLKDRAIEAQSCYSLGNTYTLLQDYEKAIDYHLKHLTIAQELNDRIGEGRACWSLGNAYTALGNHDQAMHFAEKHLEISREVGDRSGELTARLNLSDLQMVLGLSYSTNNSMISENIEIDNSLHGARPKFGRRHSMENMELMKLTPEKVQNWNSEILAKQKPLIAKPSAKLLFVNRLKGKKYKTNSSTKVLQDTSNSIDHRIPNSQRKISADSIGDEGFFDLLSRFQSNRMDDQRCCLQEKNSTSAAAAASSTPLKRMLKTPPVSVLSPNTDEFLDLLASSQSRRLDDQRASFSNLPGLRLTQNNSQSVLGHLMTNDNKEPEEDFFDILVKCQGSRLDDQRCAPPPAATKGPTVPDEDFLSLILRSQAKRMDEQRALLQRDQNRDTEFGLKDLLQSNALLELENSGKK", "length": 681 }, "evidence": [ { "id": "A0A8V0YCV2", "url": "https://omabrowser.org/oma/group/A0A8V0YCV2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P81274-1", "protein_name": "G protein-signaling modulator 2", "gene_name": "GPSM2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEENLISMREDHSFHVRYRMEASCLELALEGERLCKSGDCRAGVSFFEAAVQVGTEDLKTLSAIYSQLGNAYFYLHDYAKALEYHHHDLTLARTIGDQLGEAKASGNLGNTLKVLGNFDEAIVCCQRHLDISRELNDKVGEARALYNLGNVYHAKGKSFGCPGPQDVGEFPEEVRDALQAAVDFYEENLSLVTALGDRAAQGRAFGNLGNTHYLLGNFRDAVIAHEQRLLIAKEFGDKAAERRAYSNLGNAYIFLGEFETASEYYKKTLLLARQLKDRAVEAQSCYSLGNTYTLLQDYEKAIDYHLKHLAIAQELNDRIGEGRACWSLGNAYTALGNHDQAMHFAEKHLEISREVGDKSGELTARLNLSDLQMVLGLSYSTNNSIMSENTEIDSSLNGVRPKLGRRHSMENMELMKLTPEKVQNWNSEILAKQKPLIAKPSAKLLFVNRLKGKKYKTNSSTKVLQDASNSIDHRIPNSQRKISADTIGDEGFFDLLSRFQSNRMDDQRCCLQEKNCHTASTTTSSTPPKMMLKTSSVPVVSPNTDEFLDLLASSQSRRLDDQRASFSNLPGLRLTQNSQSVLSHLMTNDNKEADEDFFDILVKCQGSRLDDQRCAPPPATTKGPTVPDEDFFSLILRSQGKRMDEQRVLLQRDQNRDTDFGLKDFLQNNALLEFKNSGKKSADH", "length": 684 }, "evidence": [ { "id": "A0A8V0YCV2", "url": "https://omabrowser.org/oma/group/A0A8V0YCV2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8VDU0-1", "protein_name": "G protein-signaling modulator 2", "gene_name": "Gpsm2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEGNLISMREDHSFHVRYRMEASCLELALEGERLCKSGDCRAGVSFFEAAVQVGTEDLKTLSAIYSQLGNAYFYLHDYAKALEYHHHDLTLARTIGDQLGEAKASGNLGNTLKVLGNFDEAIVCCQRHLDISRELNDKVGEARALYNLGNVYHAKGKSFGCPGPQDTGEFPEDVRNALQAAVDLYEENLSLVTALGDRAAQGRAFGNLGNTHYLLGNFRDAVIAHEQRLLIAKEFGDKAAERRAYSNLGNAYIFLGEFETASEYYKKTLLLARQLKDRAVEAQSCYSLGNTYTLLQDYEKAIDYHLKHLAIAQELKDRIGEGRACWSLGNAYTALGNHDQAMHFAEKHLEISREVGDKSGELTARLNLSDLQMVLGLSYSTNNSMMSENIEIDGSLHGAGAKLGRRHSMENLELMKLTPEKVPNWNSEILAKQKPLIAKPSAKLLFVNRLKGKKYKSGSACTKVLQDASNSVDHRAPRSQKKISSDTIGDEGFFDLLRRFQSNRMDDQRCHLQGNCRTTSTAAASATPKLMKAPSVSVVSPNTDEFLDLLASSQSRRLDDQRASFSNLPGLRLTKGNSPSVLERLMTNDKKEPDEDFFDILVKCQGSRLDDQRCAPPSAATKGPTVPDEDFFSLILRSQAKRMDEQRVLLQRDPNRDSEFGLKELLQNNALLEFKHSGK", "length": 679 }, "evidence": [ { "id": "A0A8V0YCV2", "url": "https://omabrowser.org/oma/group/A0A8V0YCV2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VB22-1", "protein_name": "Partner of inscuteable", "gene_name": "pins", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSSLSASAENVSSLGLGSGGGGTTSHDGNSQQGSGSDGGSSMCLELALEGERLCKAGDCRAGVAFFQAAIQAGTEDLRTLSAIYSQLGNAYFYLGDYNKAMQYHKHDLTLAKSMNDRLGEAKSSGNLGNTLKVMGRFDEAAICCERHLTLARQLGDRLSEGRALYNLGNVYHAKGKHLGQRNPGKFGDDVKEALTRAVEFYQENLKLMRDLGDRGAQGRACGNLGNTYYLLGDFQAAIEHHQERLRIAREFGDRAAERRANSNLGNSHIFLGQFEDAAEHYKRTLALAVELGEREVEAQSCYSLGNTYTLLHEFNTAIEYHNRHLAIAQELGDRIGEARACWSLGNAHSAIGGHERALKYAEQHLQLAKELHDPVGESTARVNISDLRKLLGMPDSEPSPTEEEARSTASDHSASGNQSDGSENSQGRMVRVRRQSMEQLDLIKITPDGKRMQEEKLRAQATRKAKDDDFFEMLSRSQSKRMDDQRCSIKVNPAGAPAVATGATRKPLVQQNSLFVDPTNLPGLKSPSSANPSAIGHGPLARSATTTQQPDDDFLDMLMRCQGSRLEEQRSELPRPNVTMDAEAEAPPRSVPEAAVPGAPRGQTGRGATVPDEDFFSLIMKVQSGRMEDQRASIPFRNANNNNNSRSNNNGSAGGAGK", "length": 658 }, "evidence": [ { "id": "A0A8V0YCV2", "url": "https://omabrowser.org/oma/group/A0A8V0YCV2/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCV2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCV2" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCV2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCV2" } ], "pmid": "" }, { "name": "cell cortex", "id": "GO:0005938", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005938", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCV2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCV2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "GTPase regulator activity", "id": "GO:0030695", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030695", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCV2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCV2" } ], "pmid": "" }, { "name": "G-protein alpha-subunit binding", "id": "GO:0001965", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001965", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCV2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCV2" } ], "pmid": "" }, { "name": "GDP-dissociation inhibitor activity", "id": "GO:0005092", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005092", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCV2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCV2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "establishment of mitotic spindle orientation", "id": "GO:0000132", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000132", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCV2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCV2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 197, "end_pos": 199, "annotation": "n_glycosylation_sequon" }, { "start_pos": 376, "end_pos": 378, "annotation": "n_glycosylation_sequon" }, { "start_pos": 391, "end_pos": 393, "annotation": "n_glycosylation_sequon" }, { "start_pos": 406, "end_pos": 408, "annotation": "n_glycosylation_sequon" }, { "start_pos": 466, "end_pos": 468, "annotation": "n_glycosylation_sequon" }, { "start_pos": 9, "end_pos": 11, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 635 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 197, "end_pos": 199 }, { "start_pos": 376, "end_pos": 378 }, { "start_pos": 391, "end_pos": 393 }, { "start_pos": 406, "end_pos": 408 }, { "start_pos": 466, "end_pos": 468 }, { "start_pos": 9, "end_pos": 11 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": 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"count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YDI7-1", "uniprot_ac": "A0A8V0YDI7", "uniprot_id": "A0A8V0YDI7_CHICK", "mass": { "chemical_mass": 27946.0, "monoisotopic_mass": 27946.0 }, "refseq": {}, "gene_names": [ { "name": "RAB17", "type": "recommended", "evidence": [ { "id": "A0A8V0YDI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDI7" } ] } ], "protein_names": [ { "name": "Ras-related protein Rab-17", "type": "recommended", "evidence": [ { "id": "A0A8V0YDI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDI7/entry#names_and_taxonomy" } ] }, { "name": "3.6.5.2", "type": "synonym", "evidence": [ { "id": "A0A8V0YDI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDI7/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YDI7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDI7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RAB17", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDI7", "locus": { "chromosome": "7", "start_pos": 4845879, "end_pos": 4838440, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012215", "url": "https://www.ensembl.org/id/ENSGALG00010012215" } ] } } ], "crossref": [ { "id": "A0A8V0YDI7", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YDI7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000003899", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000003899", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd01860", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01860", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "424017", "url": "https://www.ncbi.nlm.nih.gov/gene/424017", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001806", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001806", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005225", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005225", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050209", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050209", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:424017", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424017", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "SCCKVGP", "url": "https://omabrowser.org/oma/group/SCCKVGP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YDI7", "url": "https://www.orthodb.org/?gene=A0A8V0YDI7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YEQ7", "url": "https://www.orthodb.org/?gene=A0A8V0YEQ7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1C6J7", "url": "https://www.orthodb.org/?gene=E1C6J7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47978", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47978", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47979", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47979", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00071", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00071", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "19669", "url": "https://www.rhea-db.org/rhea/19669", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YDI7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDI7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YDI7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDI7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YEQ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEQ7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YEQ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEQ7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C6J7", "url": "https://www.uniprot.org/uniprotkb/E1C6J7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C6J7-1", "url": "https://www.uniprot.org/uniprotkb/E1C6J7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSASGFEVFRSRNAVLEYLIPTTPGASLHQASIKLKDMAQTAVPGSSLGNNRPTYIYKMVLLGSTSVGKSSLAYRYVKNDFKESLPTVGCSFFTQTIQLETATIKLEIWDTAGQEKYHSVCHLYYRGAHAALLVYDLTNKETLNRAKQWLMELEKEFLPDEIVIALVGNKTDLADEREVAAEDGEEFARSRSLLFMETSAKSNHQVNDVFMAVAQELLRREGKKAAVPSTGDRQRLDLQASRTRRGCCHV", "length": 250, "header": "tr|A0A8V0YDI7-1|A0A8V0YDI7_CHICK Isoform 1 of Ras-related protein Rab-17 OS=Gallus gallus OX=9031 GN=RAB17 PE=1 SV=1 CANONICAL=A0A8V0YDI7-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YDI7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDI7/entry#A0A8V0YDI7-1", "sequence": { "sequence": "MSASGFEVFRSRNAVLEYLIPTTPGASLHQASIKLKDMAQTAVPGSSLGNNRPTYIYKMVLLGSTSVGKSSLAYRYVKNDFKESLPTVGCSFFTQTIQLETATIKLEIWDTAGQEKYHSVCHLYYRGAHAALLVYDLTNKETLNRAKQWLMELEKEFLPDEIVIALVGNKTDLADEREVAAEDGEEFARSRSLLFMETSAKSNHQVNDVFMAVAQELLRREGKKAAVPSTGDRQRLDLQASRTRRGCCHV", "length": 250, "header": "tr|A0A8V0YDI7-1|A0A8V0YDI7_CHICK Isoform 1 of Ras-related protein Rab-17 OS=Gallus gallus OX=9031 GN=RAB17 PE=1 SV=1 CANONICAL=A0A8V0YDI7-1" }, "locus": { "chromosome": "7", "start_pos": 4845551, "end_pos": 4838670, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029287.1", "url": "https://www.ensembl.org/id/ENSGALT00010029287.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017002.1", "url": "https://www.ensembl.org/id/ENSGALP00010017002.1" } ] } }, { "isoform_ac": "A0A8V0YEQ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDI7/entry#A0A8V0YEQ7-1", "sequence": { "sequence": "GSLVSAHLSTLAPHSRSCWLACLSFAFLFLQQGGSQGGRTRPFSSVEAAPILCDPCVGRDQGCIQTIQLETATIKLEIWDTAGQEKYHSVCHLYYRGAHAALLVYDLTNKETLNRAKQWLMELEKEFLPDEIVIALVGNKTDLADEREVAAEDGEEFARSRSLLFMETSAKSNHQVNDVFMAVAQELLRREGKKAAVPSTGDRQRLDLQASRTRRGCCHV", "length": 220, "header": "tr|A0A8V0YEQ7-1|A0A8V0YEQ7_CHICK Computationally mapped isoform of small monomeric GTPase OS=Gallus gallus OX=9031 GN=RAB17 PE=1 SV=1 CANONICAL=A0A8V0YDI7-1" }, "locus": { "chromosome": "7", "start_pos": 4845551, "end_pos": 4840775, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029286.1", "url": "https://www.ensembl.org/id/ENSGALT00010029286.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017000.1", "url": "https://www.ensembl.org/id/ENSGALP00010017000.1" } ] } }, { "isoform_ac": "E1C6J7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDI7/entry#E1C6J7-1", "sequence": { "sequence": "MAQTAVPGSSLGNNRPTYIYKMVLLGSTSVGKSSLAYRYVKNDFKESLPTVGCSFFTQTIQLETATIKLEIWDTAGQEKYHSVCHLYYRGAHAALLVYDLTNKETLNRAKQWLMELEKEFLPDEIVIALVGNKTDLADEREVAAEDGEEFARSRSLLFMETSAKSNHQVNDVFMAVAQELLRREGKKAAVPSTGDRQRLDLQASRTRRGCCHV", "length": 213, "header": "tr|E1C6J7-1|A0A8V0YDI7_CHICK Computationally mapped isoform of Ras-related protein Rab-17 OS=Gallus gallus OX=9031 GN=RAB17 PE=1 SV=1 CANONICAL=A0A8V0YDI7-1" }, "locus": { "chromosome": "7", "start_pos": 4845551, "end_pos": 4843216, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029293.1", "url": "https://www.ensembl.org/id/ENSGALT00010029293.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017008.1", "url": "https://www.ensembl.org/id/ENSGALP00010017008.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "gga:424017", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424017", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "B2RZ46-1", "protein_name": "Ras-related protein Rab-17", "gene_name": "Rab17", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAQAGGLPQASPSSGQPYVSKLVLLGSSSVGKTSLALRYMKQDFSNVLPTVGCAFFTKVVDLGSSSLKLEIWDTAGQEKYHSVCHLYFRGANAALLVYDITRKDSFHKAQQWLEDLEKEFHPGEVVVMLVGNKTDLGEEREVTFQEGKEFAESKSLLFMESSAKLNYQVSEIFNTIAQELLQRAGDGQSSSPQEGEAVVLNQGPTVRPRQCCA", "length": 213 }, "evidence": [ { "id": "A0A8V0YDI7", "url": "https://omabrowser.org/oma/group/A0A8V0YDI7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1N7V2-1", "protein_name": "Ras-related protein Rab-17", "gene_name": "RAB17", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAQVNGVPRPGAALGQPCIFKLVLLGSGSVGKSSLALRYVKNDFKSILPTVGCAFFTKVVDLGAACLKFEIWDTAGQEKYHSVCRLYFRGANAALLVYDITRKDSFCKAQQWLKDLEEEFHPGEVVVMLVGNKTDLEEEREVTFEEGKEFAESKGLLFMETSAKRNYQVADVFNAVARELSRREESKEGQRQRRDAPLTLSERPSWRGRCCAH", "length": 213 }, "evidence": [ { "id": "A0A8V0YDI7", "url": "https://omabrowser.org/oma/group/A0A8V0YDI7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P35292-1", "protein_name": "Ras-related protein Rab-17", "gene_name": "Rab17", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAQAAGLPQASTASGQPYVSKLVLLGSSSVGKTSLALRYMKQDFSNVLPTVGCAFFTKVLDLGSSSLKLEIWDTAGQEKYQSVCHLYFRGANAALLVYDITRKDSFHKAQQWLEDLEKEFQPGEVVVMLVGNKTDLGEEREVTFQEGKEFAESKSLLFMETSAKLNYQVSEIFNTVAQELLQRAGDTGSSRPQEGEAVALNQEPPIRQRQCCAR", "length": 214 }, "evidence": [ { "id": "A0A8V0YDI7", "url": "https://omabrowser.org/oma/group/A0A8V0YDI7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9H0T7-1", "protein_name": "Ras-related protein Rab-17", "gene_name": "RAB17", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAQAHRTPQPRAAPSQPRVFKLVLLGSGSVGKSSLALRYVKNDFKSILPTVGCAFFTKVVDVGATSLKLEIWDTAGQEKYHSVCHLYFRGANAALLVYDITRKDSFLKAQQWLKDLEEELHPGEVLVMLVGNKTDLSQEREVTFQEGKEFADSQKLLFMETSAKLNHQVSEVFNTVAQELLQRSDEEGQALRGDAAVALNKGPARQAKCCAH", "length": 212 }, "evidence": [ { "id": "A0A8V0YDI7", "url": "https://omabrowser.org/oma/group/A0A8V0YDI7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YDI7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDI7" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YDI7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDI7" } ], "pmid": "" }, { "name": "G protein activity", "id": "GO:0003925", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003925", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YDI7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDI7" } ], "pmid": "" }, { "name": "GTPase activity", "id": "GO:0003924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003924", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YDI7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDI7" } ], "pmid": "" }, { "name": "GDP binding", "id": "GO:0019003", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019003", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YDI7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDI7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 12, "go_terms": [ { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YDI7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDI7" } ], "pmid": "" }, { "name": "plasma membrane bounded cell projection assembly", "id": "GO:0120031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120031", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YDI7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDI7" } ], "pmid": "" }, { "name": "immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor", "id": "GO:0002415", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002415", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YDI7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDI7" } ], "pmid": "" }, { "name": "filopodium assembly", "id": "GO:0046847", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046847", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YDI7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDI7" } ], "pmid": "" }, { "name": "cilium assembly", "id": "GO:0060271", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060271", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YDI7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDI7" } ], "pmid": "" }, { "name": "regulation of synapse assembly", "id": "GO:0051963", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051963", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YDI7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDI7" } ], "pmid": "" }, { "name": "vesicle-mediated transport", "id": "GO:0016192", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016192", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YDI7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDI7" } ], "pmid": "" }, { "name": "regulation of filopodium assembly", "id": "GO:0051489", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051489", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YDI7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDI7" } ], "pmid": "" }, { "name": "endocytic recycling", "id": "GO:0032456", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032456", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YDI7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDI7" } ], "pmid": "" }, { "name": "melanosome transport", "id": "GO:0032402", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032402", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YDI7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDI7" } ], "pmid": "" }, { "name": "regulation of dendrite development", "id": "GO:0050773", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050773", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YDI7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDI7" } ], "pmid": "" }, { "name": "anterograde dendritic transport", "id": "GO:0098937", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098937", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YDI7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDI7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 11, "go_terms": [ { "name": "dendrite", "id": "GO:0030425", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030425", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YDI7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDI7" } ], "pmid": "" }, { "name": "melanosome", "id": "GO:0042470", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042470", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YDI7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDI7" } ], "pmid": "" }, { "name": "recycling endosome membrane", "id": "GO:0055038", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055038", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YDI7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDI7" } ], "pmid": "" }, { "name": "glutamatergic synapse", "id": "GO:0098978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098978", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YDI7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDI7" } ], "pmid": "" }, { "name": "endosome", "id": "GO:0005768", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005768", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YDI7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDI7" } ], "pmid": "" }, { "name": "basolateral plasma membrane", "id": "GO:0016323", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016323", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YDI7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDI7" } ], "pmid": "" }, { "name": "neuronal cell body", "id": "GO:0043025", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043025", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YDI7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDI7" } ], "pmid": "" }, { "name": "apical plasma membrane", "id": "GO:0016324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016324", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YDI7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDI7" } ], "pmid": "" }, { "name": "postsynapse", "id": "GO:0098794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098794", "evidence": [ { "database": "UniProtKB", "id": 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"total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1NGM2-1", "uniprot_ac": "F1NGM2", "uniprot_id": "F1NGM2_CHICK", "mass": { "chemical_mass": 72490.0, "monoisotopic_mass": 72490.0 }, "refseq": { "ac": "NP_001186342", "name": "atypical kinase COQ8A, mitochondrial", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186342" }, "gene_names": [ { "name": "COQ8A", "type": "recommended", "evidence": [ { "id": "F1NGM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NGM2" } ] }, { "name": "ADCK3", "type": "synonym", "evidence": [ { "id": "NP_001186342", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186342" } ] }, { "name": "CABC1", "type": "synonym", "evidence": [ { "id": "NP_001186342", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186342" } ] }, { "name": "COQ8A", "type": "synonym", "evidence": [ { "id": "NP_001186342", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186342" } ] }, { "name": "COQ8B", "type": "synonym", "evidence": [ { "id": "NP_001186342", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186342" } ] } ], "protein_names": [ { "name": "Atypical kinase COQ8A, mitochondrial", "type": "recommended", "evidence": [ { "id": "F1NGM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NGM2/entry#names_and_taxonomy" } ] }, { "name": "Chaperone activity of bc1 complex-like", "type": "synonym", "evidence": [ { "id": "F1NGM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NGM2/entry#names_and_taxonomy" } ] }, { "name": "Coenzyme Q protein 8A", "type": "synonym", "evidence": [ { "id": "F1NGM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NGM2/entry#names_and_taxonomy" } ] }, { "name": "aarF domain containing kinase 3", "type": "synonym", "evidence": [ { "id": "NP_001186342", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186342" } ] }, { "name": "aarF domain-containing protein kinase 3", "type": "synonym", "evidence": [ { "id": "F1NGM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NGM2/entry#names_and_taxonomy" } ] }, { "name": "atypical kinase COQ8A, mitochondrial", "type": "synonym", "evidence": [ { "id": "NP_001186342", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186342" } ] }, { "name": "chaperone activity of bc1 complex-like, mitochondrial", "type": "synonym", "evidence": [ { "id": "NP_001186342", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186342" } ] }, { "name": "chaperone, ABC1 activity of bc1 complex homolog", "type": "synonym", "evidence": [ { "id": "NP_001186342", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186342" } ] }, { "name": "coenzyme Q8B", "type": "synonym", "evidence": [ { "id": "NP_001186342", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186342" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: SRR13267655.105619.1, SRR13267656.8797.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA103992290, SAMEA103992323 [ECO:0006172] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: inferred from homology ##RefSeq-Attributes-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000062.1. On Dec 8, 2010 this sequence version replaced XP_415040.2. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001186342", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186342" } ] }, { "annotation": "Atypical kinase involved in the biosynthesis of coenzyme Q, also named ubiquinone, an essential lipid-soluble electron transporter for aerobic cellular respiration. Its substrate specificity is still unclear: may act as a protein kinase that mediates phosphorylation of COQ3. According to other reports, acts as a small molecule kinase, possibly a lipid kinase that phosphorylates a prenyl lipid in the ubiquinone biosynthesis pathway, as suggested by its ability to bind coenzyme Q lipid intermediates. However, the small molecule kinase activity was not confirmed by another publication. Shows an unusual selectivity for binding ADP over ATP.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4A1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4A1#function" }, { "database": "UniProtKB", "id": "ARBA00058956", "url": "https://www.uniprot.org/uniprotkb/ARBA00058956#function" }, { "database": "UniProtKB", "id": "F1NGM2", "url": "https://www.uniprot.org/uniprotkb/F1NGM2#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NGM2", "url": "https://www.uniprot.org/uniprotkb/F1NGM2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "COQ8A", "url": "https://www.uniprot.org/uniprotkb/F1NGM2", "locus": { "chromosome": "3", "start_pos": 12149019, "end_pos": 12180868, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010018033", "url": "https://www.ensembl.org/id/ENSGALG00010018033" } ] } } ], "crossref": [ { "id": "F1NGM2", "url": "https://alphafold.ebi.ac.uk/entry/F1NGM2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000009082", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000009082", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd13970", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13970", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "416745", "url": "https://www.ncbi.nlm.nih.gov/gene/416745", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004147", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004147", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011009", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011009", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034646", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034646", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051409", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051409", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:416745", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416745", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PEYYVPR", "url": "https://omabrowser.org/oma/group/PEYYVPR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z4A1", "url": "https://www.orthodb.org/?gene=A0A8V0Z4A1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NGM2", "url": "https://www.orthodb.org/?gene=F1NGM2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR43851", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43851", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR43851:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43851:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03109", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03109", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-2142789", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2142789", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001186342", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186342", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Z4A1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4A1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z4A1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4A1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NGM2", "url": "https://www.uniprot.org/uniprotkb/F1NGM2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NGM2-1", "url": "https://www.uniprot.org/uniprotkb/F1NGM2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAGDAIMVMRGLTKLSKAVLETQAGQLRQVILGGDAVTIAKSLQATAEEQFSSALGKMQELGKQQENLSDFSEDFGKDYDFLAQEPPDASRDFSTAPSKPHEHSSEGPAYSYTTNGPFKSVGETGDSGLGQKPFPPKMDAKLFGGFRDPGNPFAAVFGQNRAFHQDHSSVGGLTAEDIDKARQAKTEQKPYKQMLSERARERKVPVTRIGRLANFGGLAVGLGIGALAEVAKKSLRPEERSGKKAVMDSSPFLSEANAERIVRTLCKVRGAALKLGQMLSIQDDAFINPHLQRIFERVRQSADFMPIKQMMKTLNNDLGPNWRDKLESFEERPFAAASIGQVHLARLKNGKEVAMKIQYPGVAQSINSDVNNLMTVLSMSNILPEGLFPEHLIEVLSRELALECDYQREAACAKKFQELLKDHPFFYVPRVVDELCSKHVLTTELVSGFPLDQAVGLSQEIRNEICHNILVLCLRELFEFRYMQTDPNWSNFFYDPQLHKVALLDFGATRGFDEKFTDVYIEVIKAAADMDRERVLKKSIEMKFLTGYEVKEMEDAHLNAVLILGEAFASEEPFDFGNQSTTEKIHGLIPVMLKHRLVPPPEETYSLHRKMGGSFLICTKLKAKIPCKNMFEEAYSKYWSNRGKKPED", "length": 648, "header": "tr|F1NGM2-1|F1NGM2_CHICK Isoform 1 of Atypical kinase COQ8A, mitochondrial OS=Gallus gallus OX=9031 GN=COQ8A PE=1 SV=2 CANONICAL=F1NGM2-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z4A1-1", "url": "https://www.uniprot.org/uniprotkb/F1NGM2/entry#A0A8V0Z4A1-1", "sequence": { "sequence": "MAGDAIMVMRGLTKLITIAKSLQATAEEQFSSALGKMQELGKQQENLSDFSEDFGKDYDFLAQEPPDASRDFSTAPSKPHEHSSEGPAYSYTTNGPFKSVGETGDSGLGQKPFPPKMDAKLFGGFRDPGNPFAAVFGQNRAFHQDHSSVGGLTAEDIDKARQAKTEQKPYKQMLSERARERKVPVTRIGRLANFGGLAVGLGIGALAEVAKKSLRPEERSGKKAVMDSSPFLSEANAERIVRTLCKVRGAALKLGQMLSIQDDAFINPHLQRIFERVRQSADFMPIKQMMKTLNNDLGPNWRDKLESFEERPFAAASIGQVHLARLKNGKEVAMKIQYPGVAQSINSDVNNLMTVLSMSNILPEGLFPEHLIEVLSRELALECDYQREAACAKKFQELLKDHPFFYVPRVVDELCSKHVLTTELVSGFPLDQAVGLSQEIRNEICHNILVLCLRELFEFRYMQTDPNWSNFFYDPQLHKVALLDFGATRGFDEKFTDVYIEVIKAAADMDRERVLKKSIEMKFLTGYEVKEMEDAHLNAVLILGEAFASEEPFDFGNQSTTEKIHGLIPVMLKHRLVPPPEETYSLHRKMGGSFLICTKLKAKIPCKNMFEEAYSKYWSNRGKKPED", "length": 627, "header": "tr|A0A8V0Z4A1-1|A0A8V0Z4A1_CHICK Computationally mapped isoform of Atypical kinase COQ8A, mitochondrial OS=Gallus gallus OX=9031 GN=COQ8A PE=1 SV=1 CANONICAL=F1NGM2-1" }, "locus": { "chromosome": "3", "start_pos": 12171279, "end_pos": 12150189, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043592.1", "url": "https://www.ensembl.org/id/ENSGALT00010043592.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025927.1", "url": "https://www.ensembl.org/id/ENSGALP00010025927.1" } ] } }, { "isoform_ac": "F1NGM2-1", "url": "https://www.uniprot.org/uniprotkb/F1NGM2/entry#F1NGM2-1", "sequence": { "sequence": "MAGDAIMVMRGLTKLSKAVLETQAGQLRQVILGGDAVTIAKSLQATAEEQFSSALGKMQELGKQQENLSDFSEDFGKDYDFLAQEPPDASRDFSTAPSKPHEHSSEGPAYSYTTNGPFKSVGETGDSGLGQKPFPPKMDAKLFGGFRDPGNPFAAVFGQNRAFHQDHSSVGGLTAEDIDKARQAKTEQKPYKQMLSERARERKVPVTRIGRLANFGGLAVGLGIGALAEVAKKSLRPEERSGKKAVMDSSPFLSEANAERIVRTLCKVRGAALKLGQMLSIQDDAFINPHLQRIFERVRQSADFMPIKQMMKTLNNDLGPNWRDKLESFEERPFAAASIGQVHLARLKNGKEVAMKIQYPGVAQSINSDVNNLMTVLSMSNILPEGLFPEHLIEVLSRELALECDYQREAACAKKFQELLKDHPFFYVPRVVDELCSKHVLTTELVSGFPLDQAVGLSQEIRNEICHNILVLCLRELFEFRYMQTDPNWSNFFYDPQLHKVALLDFGATRGFDEKFTDVYIEVIKAAADMDRERVLKKSIEMKFLTGYEVKEMEDAHLNAVLILGEAFASEEPFDFGNQSTTEKIHGLIPVMLKHRLVPPPEETYSLHRKMGGSFLICTKLKAKIPCKNMFEEAYSKYWSNRGKKPED", "length": 648, "header": "tr|F1NGM2-1|F1NGM2_CHICK Isoform 1 of Atypical kinase COQ8A, mitochondrial OS=Gallus gallus OX=9031 GN=COQ8A PE=1 SV=2 CANONICAL=F1NGM2-1" }, "locus": { "chromosome": "3", "start_pos": 12171279, "end_pos": 12150189, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043588.1", "url": "https://www.ensembl.org/id/ENSGALT00010043588.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025925.1", "url": "https://www.ensembl.org/id/ENSGALP00010025925.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:416745", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416745", "resource": "KEGG Pathway" }, { "id": "R-GGA-2142789", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2142789", "resource": "Reactome", "description": "Ubiquinol biosynthesis" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A5G2R212-1", "protein_name": "Atypical kinase COQ8A, mitochondrial", "gene_name": "COQ8A", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAAVLGDALMLVKGLVKLTQAAVETHLQHLGLGGELVLLARTLQSTAAEQMGVIWGQVQGQERHEEPHSESFDDPQAEFHFSGPRVEDFSAAASSEQAQDHTSSQGPAPAYAASGPFREGGFPGQAAHPLGGVNRRLFADPRDPFSSTGLQRRFLHQDQSPVGGLTAEDIEKARQAKARPESKPHKQMLSERARERKVPVTRIGRLANFGGLAVGLGFGALAEVAKKSLRPEDPSGKKAVLDSSPFLSEANAERIVRTLCKVRGAALKLGQMLSIQDDAFINPHLAKIFERVRQSADFMPLKQMMVRRGGRRAALGAGVGVLGGFSGGPRPCSWPPPGISLQKTLNKDLGPSWRDKLEYFEERPFAAASIGQVHLARMKGGREVAMKIQYPGVAQSINSDVNNLMAVLNMSNMLPEGLFPEHLIDVLRRELALECDYQREAACARKFRELLKDHPFFYVPEIVDELCSPHVLTTELVSGFPLDQAEGLSQEIRNEICYNILVLCLRELFEFHFMQTDPNWSNFFYDPQQHRVALLDFGATREYDRSFTDLYIQVIRAAADQDREAVLKKSIEMKFLTGYEVKAMEDAHLDAILILGEAFASEEPFDFGTQSTTEKIHNLIPIMLKHRLVPPPEETYSLHRKMGGSFLICSKLKARFPCKAMFEEAYSNYRRRQAEQQ", "length": 677 }, "evidence": [ { "id": "F1NGM2", "url": "https://omabrowser.org/oma/group/F1NGM2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3HV77-1", "protein_name": "Atypical kinase COQ8A, mitochondrial", "gene_name": "Coq8a", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAAMLGDAIMVAKGLAKLTQAAVETHLQNLGLGGELILAARALQSTAVEQISMVFGKVQGQDKHEDLYATENFEDLEAEVQFSTPQAAETSLDFSATSSPDQSLSSSLGHAHSEGPAPTYVSSGPFREAGLSGQATSPMGRVNGRLFVNTRDLFLASGIQRRFFHQDQSPVGGLTAEDIEKARQAKARPESKPHKQMLSERARERKVPVTRIGRLANFGGLAVGLGFGALAEVAKKSLRPENSTGKKAVLDSSPFLSEANAERIVSTLCKVRGAALKLGQMLSIQDDAFINPHLAKIFERVRQSADFMPLKQMTKTLNNDLGPHWRDKLEYFEERPFAAASIGQVHLARMKGGREVAMKIQYPGVAQSINSDVNNLMAVLNMSNMLPEGLFPEHLIDVLRRELVLECDYQREAAYAKKFRELLKDHPFFYVPEIVDELCSPHVLTTELITGFPLDQAEGLSQEVRNEICYNILVLCLRELFEFHVMQTDPNWSNFFYDPQQHKVALLDFGATREYDRSFTDLYIQVIRAAADQDREAVLKKSIEMKFLTGYEVKAMEDAHLDAILILGEAFASEEPFDFGTQSTTEKIHNLIPVMLKHRLIPPPEETYSLHRKMGGSFLICSKLKARFPCKTMFEEAYSNYCRMKSGLQ", "length": 649 }, "evidence": [ { "id": "F1NGM2", "url": "https://omabrowser.org/oma/group/F1NGM2/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P27697-1", "protein_name": "Atypical kinase COQ8, mitochondrial", "gene_name": "COQ8", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MVTNMVKLRNLRRLYCSSRLLRTIQNGRISSVSSISLSKKYTTKSAKEGEENVERKHEEEKKDTLKSSSVPTSRISRLFHYGSLAAGVGMNAAAKGISEVAKGNSPTWKSLILSDSNIDRITNKFSKMRGVALKIGQLLSFQDEKVLPKELYEILSRVQNSANHMPQRQLEKVMAKELGANWKTKFSKFDKIPMAAASIGQVHAAELPSGQRVVVKIQYPGVKESIDSDLNSLLMLLTASSLLPKGLFLDKTIANARTELKWECDYNREARALQKFEALLKDDPAFEVPHVFPEYTTDNIITMTRMEGTEIMKLPKASQETKNFISENIMRLCLEEIATFKYMQTDPNWANFLYNGRTKKIELLDFGASRPFAEDFILKYRKLLTYATLRDRKGAYEMSVQLGYLTGLESQSMKDAHVDSVLTLGEPFRGDVDKSFDFKDQTVSDRIRGNIGLMLNERLCPPPEETYSLHRKFSGIFLLCARMGASVHCAKLFKEIFAYKV", "length": 501 }, "evidence": [ { "id": "F1NGM2", "url": "https://omabrowser.org/oma/group/F1NGM2/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q29RI0-1", "protein_name": "Atypical kinase COQ8A, mitochondrial", "gene_name": "COQ8A", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAAMLGDAIMLIKGFVKLTQAAVETHLQHLGLSGELLMAVRALQSTATEQVGMVFGQVQGQETPEEYYSESLDDPEGAFHFSGMRAESASADVSAASSPEQSPPPWAHAAGSEGPAPAYVASAPFREGGVLGQAASPLGRVNGRLFASPRDPFSAPGLQRRVYHQDQSSMGGLTAEDIEKARQAKARPESKPHKQALSEHARERKVPVTRIGRLANFGGLAVGLGFGALAEVAKKSLRPDDPSGKKAVLDSSPFLSEANAERIVRTLCKVRGAALKLGQMLSIQDDAFINPHLAKIFDRVRQSADFMPLKQMMKTLNNDLGPNWRDKLEYFEERPFAAASIGQVHLARLKGGREVAMKIQYPGVAQSINSDVNNLMTVLNMSNMLPEGLFPEHLIDVLRRELALECDYQREAACARRFRELLKDHPFFYVPEIVDELCSPHVLTTELVSGFPLDQAEGLSQEIRNEICYNILVLCLRELFEFQFMQTDPNWSNFFYDPELHKVALLDFGATREFDRSFTDLYIQIIRAAANQDREAVLKKSIEMKFLTGYEVKAMEDAHLDAILILGEAFASEEPFDFGTQSTTEKIHNLIPIMLKHRLVPPPEETYSLHRKMGGSFLICSKLKARFPCKAMFEEAYSNYCRRQAEQQ", "length": 648 }, "evidence": [ { "id": "F1NGM2", "url": "https://omabrowser.org/oma/group/F1NGM2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q54IH6-1", "protein_name": "Probable serine/threonine-protein kinase abkA", "gene_name": "abkA", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MGGRLNDLIQVAYGGKNVILSMMKNKTRQTSSVFINNLNSLNNNNNNISLKDKFKDLKDLKDNLNEKKINNDNDDDDEDNLIFDEKKDFLNENKNPELNYIKSKGHKIPSSQTSRFWEFTKLAVGVGAGFLGEKTKRTIDSSSSSSSPSSSYSAIFTDTNAERMAESFSRMRGAALKIGQVLSIQDESFLPPKFVEILDRVRKNANPIPLEQLYNTMSNELGENWRSKFQLFQDDPIAAASIGQVHRAITLDGKEVAVKVQYPGVADSITSDIKNLSSLLKMIVPETAYIEKSLESARSELLLETDYLNEASNQLKFKSLLESSINSGTNGSFKYLKDLYVPNVIMELTTKRILTTEFVHGTSIDKITIENHNQETRDWISKNILSLCLAELFEFNFMQVDPNWTNFVVDFENKRINLLDFGACRNYKSEFLFNYLKSIEGGVNRDINQILEYSLKLGYLTGDENKQMNDAQAKSILILSEPFSKLYYKENNLKTYPFNEKQIAKRISQLIPTMLKNRLKPPPEETYSLHRKLSGCYLVCSKLKSNINSTLIFNHFKNIFYKNYK", "length": 565 }, "evidence": [ { "id": "F1NGM2", "url": "https://omabrowser.org/oma/group/F1NGM2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q5BJQ0-1", "protein_name": "Atypical kinase COQ8A, mitochondrial", "gene_name": "Coq8a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAAMLGDAIMVAKGLAKLTQAAVETHLQNLGLGGELILAARALQSTAVEQISMVFGKVQGQDKHEDSYATENFEDLEAEVQFSTPQAAGSSPDFSTASSLDQPLSSSLGHAHREGPAPAYVSSGPFREAGLSGQATSPLGRVNGRLFVDCRDLFLANSIQRRFFHQDQAPVGGLTAEDIEKARQAKARPESKPHKQMLSERARERKVPVTRIGRLANFGGLAVGLGFGALAEVAKKSLRSENSTGKKAVLDSSPFLSEANAERIVSTLCKVRGAALKLGQMLSIQDDAFINPHLAKIFERVRQSADFMPLKQMTKTLNNDLGPHWRDKLEYFEERPFAAASIGQVHLARLKGGREVAMKIQYPGVAQSINSDVNNLMAVLNMSNMLPEGLFPEHLIDVLRRELTLECDYQREAAYAKKFRELLKDHPFFYVPEIVDELCSPHVLTTELITGFPLDQAEGLSQEVRNEICYNILVLCLRELFEFHVMQTDPNWSNFFYDPQQHKVALLDFGATREYDRSFTDLYIQVIRAAADQDREAVLKKSIEMKFLTGYEVKAMEDAHLDAILILGEAFASEEPFDFGTQSTTEKIHNLIPIMLKHRLIPPPEETYSLHRKMGGSFLICSKLKACFPCKAMFEEAYSNYCRMKSGLQ", "length": 649 }, "evidence": [ { "id": "F1NGM2", "url": "https://omabrowser.org/oma/group/F1NGM2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q60936-1", "protein_name": "Atypical kinase COQ8A, mitochondrial", "gene_name": "Coq8a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAMLGDAIMVAKGLAKLTQAAVETHLQNLGLGGELLLAARALQSTAVEQFSMVFGKVQGQDKHEDSYATENFEDLEAEVQFSTPQAAGTSLDFSAASSLDQSLSPSHSQGPAPAYASSGPFREAGLPGQATSPMGRVNGRLFVDHRDLFLANGIQRRSFHQDQSSVGGLTAEDIEKARQAKARPESKPHKQMLSERARERKVPVTRIGRLANFGGLAVGLGIGALAEVAKKSLRSENSTGKKAVLDSSPFLSEANAERIVSTLCKVRGAALKLGQMLSIQDDAFINPHLAKIFERVRQSADFMPLKQMTKTLNSDLGPHWRDKLEYFEERPFAAASIGQVHLARMKGGREVAMKIQYPGVAQSINSDVNNLMAVLNMSNMLPEGLFPEHLIDVLRRELTLECDYQREAAYAKKFRELLKDHPFFYVPEIVDELCSPHVLTTELISGFPLDQAEGLSQEVRNEICYNILVLCLRELFEFHVMQTDPNWSNFFYDPQQHKVALLDFGATREYDRSFTDLYIQVIRAAADQDREAVLKKSIEMKFLTGYEVKAMEDAHLDAILILGEAFASEEPFDFGTQSTTEKIHNLIPVMLKHRLIPPPEETYSLHRKMGGSFLICSKLKARFPCKAMFEEAYSNYCRMKSGLQ", "length": 645 }, "evidence": [ { "id": "F1NGM2", "url": "https://omabrowser.org/oma/group/F1NGM2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8NI60-1", "protein_name": "Atypical kinase COQ8A, mitochondrial", "gene_name": "COQ8A", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAILGDTIMVAKGLVKLTQAAVETHLQHLGIGGELIMAARALQSTAVEQIGMFLGKVQGQDKHEEYFAENFGGPEGEFHFSVPHAAGASTDFSSASAPDQSAPPSLGHAHSEGPAPAYVASGPFREAGFPGQASSPLGRANGRLFANPRDSFSAMGFQRRFFHQDQSPVGGLTAEDIEKARQAKARPENKQHKQTLSEHARERKVPVTRIGRLANFGGLAVGLGFGALAEVAKKSLRSEDPSGKKAVLGSSPFLSEANAERIVRTLCKVRGAALKLGQMLSIQDDAFINPHLAKIFERVRQSADFMPLKQMMKTLNNDLGPNWRDKLEYFEERPFAAASIGQVHLARMKGGREVAMKIQYPGVAQSINSDVNNLMAVLNMSNMLPEGLFPEHLIDVLRRELALECDYQREAACARKFRDLLKGHPFFYVPEIVDELCSPHVLTTELVSGFPLDQAEGLSQEIRNEICYNILVLCLRELFEFHFMQTDPNWSNFFYDPQQHKVALLDFGATREYDRSFTDLYIQIIRAAADRDRETVRAKSIEMKFLTGYEVKVMEDAHLDAILILGEAFASDEPFDFGTQSTTEKIHNLIPVMLRHRLVPPPEETYSLHRKMGGSFLICSKLKARFPCKAMFEEAYSNYCKRQAQQ", "length": 647 }, "evidence": [ { "id": "F1NGM2", "url": "https://omabrowser.org/oma/group/F1NGM2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9SBB2-1", "protein_name": "Protein ABC transporter 1, mitochondrial", "gene_name": "ABC1", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSSWSKSFTRLVNGVSLVAKEIYNQSPELQRARNGDLEGLITSSGKKALVAATDLVGLTSGKLRELSIRRSKEPSVVYFDEGDNKDNVVATPEVRSVNTKPSEKIVDSKVLRNEFSDEVKNSNREGEIKVSGVEAGEIIGVRAVESGTVTEASSPSEVVPPVKRRRPRERKVPSTPMARAYGFFNLGAALAWGAVKESTYRMVNGTPMTPDNQPALSSLMSKENAERLALGLCEMRGAALKVGQMLSIQDESLVPAPILNALEYVRQGADVMPRSQLNPVLDAELGSNWQSKLTSFDYEPLAAASIGQVHRAVTKDGLEVAMKIQYPGVANSIESDIENVRRLLNYTNLIPKGLFLDRAIKVAKEELAQECDYEIEAVSQKRFRDLLSDTPGFYVPLVVDETSSKKILTTELISGIPIDKVALLDQKTRDYVGRKMLELTLKELFVFRFMQTDPNWGNFLYNEATKTINLIDFGAARDYPKKFVDDYLRMVMACAEKDSEGVIEMSRRLGFLTGDESDVMLDAHVQAGFIVGLPFAEPGGYAFRTNNIASSISNLGATMLKHRLSPPPDEAYSLHRKLSGAFLACIKLGATVPCRDLLLQVYNKYQFDDEPQDPVVATSSVSS", "length": 623 }, "evidence": [ { "id": "F1NGM2", "url": "https://omabrowser.org/oma/group/F1NGM2/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9VYI6-1", "protein_name": "Coenzyme Q8", "gene_name": "Coq8", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSRSAQEAAALLRGLRILLEACGREHLAHGRHLWSNSSIRELIAENVAHTQQLVRSSSQNPTEELKKLQQTVKETGERGYVVAKGICSLLETKIKMSREESAISEPAQVSSIRKSTPTAQNPASWDAANLDISSITLQEFEEILSRRNKDRSVSLRTPATKSNQTMPKKETSTNPGIITQDTEYVNNVLRFVAGAKVEEQPPDAQPKKKSDQPAIEVPELSKVAKQRKVPSSRIGRMASFGGLFAGLGLGTLNELTKGALGLGGSTSMREALLSPANAERIVDTLCKVRGAALKIGQILSIQDSSVVSPQLAKAFERVRQAADYMPDWQVERVMNTQLGADWRQRLKSFEDKPFAAASIGQVHRATLSDGMDVAIKIQYPGVAQSIESDIDNLVGMLKVWDVFPQGFFIDNVVRVAKRELQWEVDYDREAEYTEKFREMIAPYPEYYVPRVVRDLTTSSVLTTELVPGVPLDKCFDLSYEHRRHIAASVLKLCLRELFEIECMQTDPNWSNFLYDAPSRRLMLIDFGSTRFYRHEFIRNYRRVIMSAAENNRQGVLEMSREMGFLTGYETKQMEQAHVDAVMILGEIFRYDGDFDFGRQNTTERLAALVPTMVAHRLCPPPEEIYSIHRKLSGIFLLCARLNVRMNCVPFYKDIVLGKFKD", "length": 661 }, "evidence": [ { "id": "F1NGM2", "url": "https://omabrowser.org/oma/group/F1NGM2/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "extrinsic component of mitochondrial inner membrane", "id": "GO:0031314", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031314", "evidence": [ { "database": "UniProtKB", "id": "F1NGM2", "url": "https://www.uniprot.org/uniprotkb/F1NGM2" } ], "pmid": "" }, { "name": "mitochondrial membrane", "id": "GO:0031966", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031966", "evidence": [ { "database": "UniProtKB", "id": "F1NGM2", "url": "https://www.uniprot.org/uniprotkb/F1NGM2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "F1NGM2", "url": "https://www.uniprot.org/uniprotkb/F1NGM2" } ], "pmid": "" }, { "name": "enzyme activator activity", "id": "GO:0008047", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008047", "evidence": [ { "database": "UniProtKB", "id": "F1NGM2", "url": "https://www.uniprot.org/uniprotkb/F1NGM2" } ], "pmid": "" }, { "name": "ADP binding", "id": "GO:0043531", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043531", "evidence": [ { "database": "UniProtKB", "id": "F1NGM2", "url": "https://www.uniprot.org/uniprotkb/F1NGM2" } ], "pmid": "" }, { "name": "kinase activity", "id": "GO:0016301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016301", "evidence": [ { "database": "UniProtKB", "id": "F1NGM2", "url": "https://www.uniprot.org/uniprotkb/F1NGM2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "ubiquinone biosynthetic process", "id": "GO:0006744", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006744", "evidence": [ { "database": "UniProtKB", "id": "F1NGM2", "url": "https://www.uniprot.org/uniprotkb/F1NGM2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 488, "end_pos": 490, "annotation": "n_glycosylation_sequon" }, { "start_pos": 578, "end_pos": 580, "annotation": "n_glycosylation_sequon" }, { "start_pos": 67, "end_pos": 69, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1NGM2-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 648, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1NGM2-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1NGM2" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1NGM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NGM2" }, { "id": "PF03109", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03109" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "ABC1 atypical kinase-like", "eco_id": "ECO_0000259", "start_pos": 298, "end_pos": 537, "start_aa": "Val", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 488, "end_pos": 490 }, { "start_pos": 578, "end_pos": 580 }, { "start_pos": 67, "end_pos": 69 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1NGQ3-1", "uniprot_ac": "F1NGQ3", "uniprot_id": "F1NGQ3_CHICK", "mass": { "chemical_mass": 35413.0, "monoisotopic_mass": 35413.0 }, "refseq": { "ac": "NP_001264928", "name": "lymphokine-activated killer T-cell-originated protein kinase", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264928" }, "gene_names": [ { "name": "PBK", "type": "recommended", "evidence": [ { "id": "F1NGQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NGQ3" } ] }, { "name": "PBK", "type": "synonym", "evidence": [ { "id": "NP_001264928", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264928" } ] } ], "protein_names": [ { "name": "PDZ binding kinase", "type": "synonym", "evidence": [ { "id": "F1NGQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NGQ3/entry#names_and_taxonomy" } ] }, { "name": "T-LAK cell-originated protein kinase", "type": "synonym", "evidence": [ { "id": "NP_001264928", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264928" } ] }, { "name": "lymphokine-activated killer T-cell-originated protein kinase", "type": "synonym", "evidence": [ { "id": "NP_001264928", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264928" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: BX934024.1, BU108568.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BX934024.1, BU406153.1, BU203035.1 and CV860416.1. On May 5, 2013 this sequence version replaced XP_420011.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001264928", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264928" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NGQ3", "url": "https://www.uniprot.org/uniprotkb/F1NGQ3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PBK", "url": "https://www.uniprot.org/uniprotkb/F1NGQ3", "locus": { "chromosome": "3", "start_pos": 104959904, "end_pos": 104951538, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010010218", "url": "https://www.ensembl.org/id/ENSGALG00010010218" } ] } } ], "crossref": [ { "id": "F1NGQ3", "url": "https://alphafold.ebi.ac.uk/entry/F1NGQ3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000016582", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000016582", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd14001", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14001", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "422003", "url": "https://www.ncbi.nlm.nih.gov/gene/422003", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000719", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000719", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008271", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008271", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011009", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011009", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:422003", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422003", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MIMDIAH", "url": "https://omabrowser.org/oma/group/MIMDIAH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1NGQ3", "url": "https://www.orthodb.org/?gene=F1NGQ3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR43289", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43289", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR43289:SF14", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43289:SF14", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00069", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00069", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001264928", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264928", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1NGQ3", "url": "https://www.uniprot.org/uniprotkb/F1NGQ3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NGQ3-1", "url": "https://www.uniprot.org/uniprotkb/F1NGQ3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "METSKSQSSLDQKEKPGPASITIPASPSMQKLGYGTGVNVYLMKRSPRGLSRSPWAVKKINSKCSKNQQNIYQSRLNEEAKILKSLKHPNIVGYRAFTEANDGSMCLVMEFGGEKSLNDLIEERNAARLGPFPAATISKVALSMARGLKYLHNDKKLLHGDIKSPNVVVKGDFEAIKICDVGVSLPLDENLTVSDPTVHYIGTEPWKPKEALSDDGVITDKADIFSFGLTLWEMMTLSVPHLNLGSSTDDEDESFDEDDFDEEAYYAALGTRPALNMDELDSSYQQVIELFSICTSEDPKKRPSAAHVVAVLEASLPPELRA", "length": 322, "header": "tr|F1NGQ3-1|F1NGQ3_CHICK Isoform 1 of PDZ binding kinase OS=Gallus gallus OX=9031 GN=PBK PE=4 SV=3 CANONICAL=F1NGQ3-1" }, "isoforms": [ { "isoform_ac": "F1NGQ3-1", "url": "https://www.uniprot.org/uniprotkb/F1NGQ3/entry#F1NGQ3-1", "sequence": { "sequence": "METSKSQSSLDQKEKPGPASITIPASPSMQKLGYGTGVNVYLMKRSPRGLSRSPWAVKKINSKCSKNQQNIYQSRLNEEAKILKSLKHPNIVGYRAFTEANDGSMCLVMEFGGEKSLNDLIEERNAARLGPFPAATISKVALSMARGLKYLHNDKKLLHGDIKSPNVVVKGDFEAIKICDVGVSLPLDENLTVSDPTVHYIGTEPWKPKEALSDDGVITDKADIFSFGLTLWEMMTLSVPHLNLGSSTDDEDESFDEDDFDEEAYYAALGTRPALNMDELDSSYQQVIELFSICTSEDPKKRPSAAHVVAVLEASLPPELRA", "length": 322, "header": "tr|F1NGQ3-1|F1NGQ3_CHICK Isoform 1 of PDZ binding kinase OS=Gallus gallus OX=9031 GN=PBK PE=4 SV=3 CANONICAL=F1NGQ3-1" }, "locus": { "chromosome": "3", "start_pos": 104959590, "end_pos": 104951932, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010024311.1", "url": "https://www.ensembl.org/id/ENSGALT00010024311.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010013824.1", "url": "https://www.ensembl.org/id/ENSGALP00010013824.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:422003", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422003", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "F1RJR9-1", "protein_name": "PDZ binding kinase", "gene_name": "PBK", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEESSNFKTPSKLSEKKKPTLCLTPCINIPASPFMQKLGYGTGVNVYLMKRSPRGLSHSPWAVKKINPRCNDYYQSMYQKRLTDEAKILKSLNHPNIIGYRAFTEASDGSLCLAMEYGGEKSLNDLIEERNKDSQDPFPAAIILKVALNMARGLKYLHQEKKLLHGDIKSSNVVIKGDFETIKICDVGVSLPLDENMTVTDPEAYYIGTEPWKPKEALEENGIITDKADIFAFGLTLWEMMTLSIPHISLPDDDDEDKTFDESDFDDEAYYAALGTRPPINMEELDATYQKVIELFSVCTNEDPKDRPSAAHIVAALEMDVL", "length": 322 }, "evidence": [ { "id": "F1NGQ3", "url": "https://omabrowser.org/oma/group/F1NGQ3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3HNI7-1", "protein_name": "Lymphokine-activated killer T-cell-originated protein kinase", "gene_name": "Pbk", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MEGINNFKTPNKLSEKRKSVLCSTPCVTIPASPFMQKLGFGTGVNVYLMKRSPRGLSHSPWAVKKINPLCNDHYRTVYQKRLTDEAKILKNLNHPNIIGYRAFTEASDGSLCLAMEYGGEKSLNDLIEERNKDSGSPFPAAVILKVALHMARGLKYLHQEKKLLHGDIKSSNVVIKGDFETIKICDVGVSLPLDENMTVTDPEACYIGTEPWKPKEALDENGIITDKADMFAFGLTLWEMMTLCIPHINLPEDDDDEDATFDESDFDDEAYYAALGTRPSINMEELDESYQKVIELFSVCTNEDPKDRPSAAHIVEALELDVQ", "length": 323 }, "evidence": [ { "id": "F1NGQ3", "url": "https://omabrowser.org/oma/group/F1NGQ3/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q6DHU8-1", "protein_name": "Lymphokine-activated killer T-cell-originated protein kinase homolog", "gene_name": "pbk", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEASKESPSAFKTPCKPAKVKSPVNACGTPVTIPASPFMKKLGCGTGVNVYLMNRMGKQTHSPWAIKKINSKCAQGQVSVYQKRLCEEAKILKDLKHPNIVGFRAFTTAKDGSKCLAMEFGGEQSLNDLIEKRREEGLQAFPVDTIEKVALHVARGLLYLHNEKKLLHGDMKSCNVVIKGDFESIKICDVGVSLPLDENMQVSDPKAHYIGTEPWKPKEALEDGVITDKADIFAYGLTLWEMMTLSVPHLEMLDTEGDEDDDDESFEEDFDEDAYYERLGSRPALDAVTLGGSYQRMVELFCLCTEEDPQKRPSAAHIVQVLESNSQLSKQNTEVIVID", "length": 339 }, "evidence": [ { "id": "F1NGQ3", "url": "https://omabrowser.org/oma/group/F1NGQ3/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q96KB5-1", "protein_name": "Lymphokine-activated killer T-cell-originated protein kinase", "gene_name": "PBK", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEGISNFKTPSKLSEKKKSVLCSTPTINIPASPFMQKLGFGTGVNVYLMKRSPRGLSHSPWAVKKINPICNDHYRSVYQKRLMDEAKILKSLHHPNIVGYRAFTEANDGSLCLAMEYGGEKSLNDLIEERYKASQDPFPAAIILKVALNMARGLKYLHQEKKLLHGDIKSSNVVIKGDFETIKICDVGVSLPLDENMTVTDPEACYIGTEPWKPKEAVEENGVITDKADIFAFGLTLWEMMTLSIPHINLSNDDDDEDKTFDESDFDDEAYYAALGTRPPINMEELDESYQKVIELFSVCTNEDPKDRPSAAHIVEALETDV", "length": 322 }, "evidence": [ { "id": "F1NGQ3", "url": "https://omabrowser.org/oma/group/F1NGQ3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9JJ78-1", "protein_name": "Lymphokine-activated killer T-cell-originated protein kinase", "gene_name": "Pbk", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEGINNFKTPNKSEKRKSVLCSTPCVNIPASPFMQKLGFGTGVSVYLMKRSPRGLSHSPWAVKKISLLCDDHYRTVYQKRLTDEAKILKNLNHPNIIGYRAFTEASDGSLCLAMEYGGEKSLNDLIEERNKDSGSPFPAAVILRVALHMARGLKYLHQEKKLLHGDIKSSNVVIKGDFETIKICDVGVSLPLDENMTVTDPEACYIGTEPWKPKEALEENGIITDKADVFAFGLTLWEMMTLCIPHVNLPDDDVDEDATFDESDFDDEAYYAALGTRPSINMEELDDSYQKAIELFCVCTNEDPKDRPSAAHIVEALELDGQCCGLSSKH", "length": 330 }, "evidence": [ { "id": "F1NGQ3", "url": "https://omabrowser.org/oma/group/F1NGQ3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "F1NGQ3", "url": "https://www.uniprot.org/uniprotkb/F1NGQ3" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "F1NGQ3", "url": "https://www.uniprot.org/uniprotkb/F1NGQ3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1NGQ3", "url": "https://www.uniprot.org/uniprotkb/F1NGQ3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 190, "end_pos": 192, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1NGQ3-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 322, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1NGQ3-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1NGQ3" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 190, "end_pos": 192 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1NGS3-1", "uniprot_ac": "F1NGS3", "uniprot_id": "F1NGS3_CHICK", "mass": { "chemical_mass": 42026.0, "monoisotopic_mass": 42026.0 }, "refseq": {}, "gene_names": [ { "name": "TPST2", "type": "recommended", "evidence": [ { "id": "F1NGS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NGS3" } ] } ], "protein_names": [ { "name": "Protein-tyrosine sulfotransferase", "type": "recommended", "evidence": [ { "id": "F1NGS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NGS3/entry#names_and_taxonomy" } ] }, { "name": "2.8.2.20", "type": "synonym", "evidence": [ { "id": "F1NGS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NGS3/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Catalyzes the O-sulfation of tyrosine residues within acidic motifs of polypeptides, using 3'-phosphoadenylyl sulfate (PAPS) as cosubstrate.", "evidence": [ { "database": "UniProtKB", "id": "F1NGS3", "url": "https://www.uniprot.org/uniprotkb/F1NGS3#function" }, { "database": "UniProtKB", "id": "ARBA00003886", "url": "https://www.uniprot.org/uniprotkb/ARBA00003886#function" }, { "database": "UniProtKB", "id": "RU365018", "url": "https://www.uniprot.org/uniprotkb/RU365018#function" }, { "database": "UniProtKB", "id": "A0A8V0ZX23", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZX23#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NGS3", "url": "https://www.uniprot.org/uniprotkb/F1NGS3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TPST2", "url": "https://www.uniprot.org/uniprotkb/F1NGS3", "locus": { "chromosome": "15", "start_pos": 7174149, "end_pos": 7184414, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010023601", "url": "https://www.ensembl.org/id/ENSGALG00010023601" } ] } } ], "crossref": [ { "id": "F1NGS3", "url": "https://alphafold.ebi.ac.uk/entry/F1NGS3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000005626", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000005626", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "416910", "url": "https://www.ncbi.nlm.nih.gov/gene/416910", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR026634", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026634", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:416910", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416910", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "VMMDSNH", "url": "https://omabrowser.org/oma/group/VMMDSNH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZX23", "url": "https://www.orthodb.org/?gene=A0A8V0ZX23", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NGS3", "url": "https://www.orthodb.org/?gene=F1NGS3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12788", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12788", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12788:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12788:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13469", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13469", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-156584", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-156584", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001012812", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012812", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "16801", "url": "https://www.rhea-db.org/rhea/16801", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0ZX23", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZX23", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZX23-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZX23-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NGS3", "url": "https://www.uniprot.org/uniprotkb/F1NGS3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NGS3-1", "url": "https://www.uniprot.org/uniprotkb/F1NGS3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRVTMRRVLLAVGSVVALMVTLHLGQQVLECQHVLSKRRHRLMRPENEELVMVDSNHVEYRYSKEMPLIFIGGVPRSGTTLMRAMLDAHPEVRCGEETRIIPRVLAMRQAWSKSGREKMRLDEAGVTDQVLDAAMQAFILEVIAKHGEPARYLCNKDPFTLKSSVYLSRLFPNSKFLLMVRDGRASVHSMITRKVTIAGFDLNSYRDCLTKWNKAIEVMYSQCLEIGRSRCLPVYYEQLVLHPEQSMHAIMKFLGISWSDTVLHHEELIGKPGGVSLSKIERSTDQVIKPVNMEALSKWIGHIPGDVLQDMAHIAPMLARLGYDPYANPPNYGHPDPLVVNNTHRVLKGDYKTPANLKGHLQVTQNTSSSH", "length": 371, "header": "tr|F1NGS3-1|F1NGS3_CHICK Isoform 1 of Protein-tyrosine sulfotransferase OS=Gallus gallus OX=9031 GN=TPST2 PE=3 SV=1 CANONICAL=F1NGS3-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZX23-1", "url": "https://www.uniprot.org/uniprotkb/F1NGS3/entry#A0A8V0ZX23-1", "sequence": { "sequence": "MRVTMRRVLLAVGSVVALMVTLHLGQQVLECQHVLSKRRHRLMRPENEELVMVDSNHVEYRYSKEMPLIFIGGVPRSGTTLMRAMLDAHPEVRCGEETRIIPRVLAMRQAWSKSGREKMRLDEAGVTDQVLDAAMQAFILEVIAKHGEPARYLCNKDPFTLKSSVYLSRLFPNSKFLLMVRDGRASVHSMITRKVTIAGFDLNSYRDCLTKWNKAIEVMYSQCLEIGRSRCLPVYYEQLVLHPEQSMHAIMKFLGISWSDTVLHHEELIGKPGGVSLSKIERSTDQVIKPVNMEALSKWIGHIPGDVLQDMAHIAPMLARLGYDPYANPPNYGHPDPLVVNNTHRVLKGDYKTPANLKGHLQIGPPA", "length": 367, "header": "tr|A0A8V0ZX23-1|A0A8V0ZX23_CHICK Computationally mapped isoform of Protein-tyrosine sulfotransferase OS=Gallus gallus OX=9031 GN=TPST2 PE=3 SV=1 CANONICAL=F1NGS3-1" }, "locus": { "chromosome": "15", "start_pos": 7179022, "end_pos": 7175638, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010057458.1", "url": "https://www.ensembl.org/id/ENSGALT00010057458.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034917.1", "url": "https://www.ensembl.org/id/ENSGALP00010034917.1" } ] } }, { "isoform_ac": "F1NGS3-1", "url": "https://www.uniprot.org/uniprotkb/F1NGS3/entry#F1NGS3-1", "sequence": { "sequence": "MRVTMRRVLLAVGSVVALMVTLHLGQQVLECQHVLSKRRHRLMRPENEELVMVDSNHVEYRYSKEMPLIFIGGVPRSGTTLMRAMLDAHPEVRCGEETRIIPRVLAMRQAWSKSGREKMRLDEAGVTDQVLDAAMQAFILEVIAKHGEPARYLCNKDPFTLKSSVYLSRLFPNSKFLLMVRDGRASVHSMITRKVTIAGFDLNSYRDCLTKWNKAIEVMYSQCLEIGRSRCLPVYYEQLVLHPEQSMHAIMKFLGISWSDTVLHHEELIGKPGGVSLSKIERSTDQVIKPVNMEALSKWIGHIPGDVLQDMAHIAPMLARLGYDPYANPPNYGHPDPLVVNNTHRVLKGDYKTPANLKGHLQVTQNTSSSH", "length": 371, "header": "tr|F1NGS3-1|F1NGS3_CHICK Isoform 1 of Protein-tyrosine sulfotransferase OS=Gallus gallus OX=9031 GN=TPST2 PE=3 SV=1 CANONICAL=F1NGS3-1" }, "locus": { "chromosome": "15", "start_pos": 7179022, "end_pos": 7175201, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010057461.1", "url": "https://www.ensembl.org/id/ENSGALT00010057461.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034919.1", "url": "https://www.ensembl.org/id/ENSGALP00010034919.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "gga:416910", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416910", "resource": "KEGG Pathway" }, { "id": "R-GGA-156584", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-156584", "resource": "Reactome", "description": "Cytosolic sulfonation of small molecules" } ], "orthologs": [ { "uniprot_canonical_ac": "G3HTC1-1", "protein_name": "Protein-tyrosine sulfotransferase", "gene_name": "Tpst2", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MRRAPCLGLGPWLGMRLSVRKVLLAAGCTLALLLALQLGQQVLECRAVLGGKRSARRMRPEQEELVMLGADQVEYRYGKAMPLIFVGGVPRSGTTLMRAMLDAHPEVRCGEETRIIPRVLAMRQAWSKSGREKLRLDEAGVTDEVLDAAMQAFILEVIAKHGEPARVLCNKDPFTLKSSVYLARLFPNSKFLLMVRDGRASVHSMITRKVTIAGFDLSSYRDCLTKWNKAIEVMYAQCMEVGRDKCLPVYYEQLVLHPRRSLKRILDFLGIAWSDTVLHHEDLIGKPGGVSLSKIERSTDQVIKPVNLEALSKWTGHIPGDVVRDMAQIAPMLARLGYDPYANPPNYGNPDPIVINNTHRVLKGDYKTPANLKGYFQVNQNSTSPHLGSS", "length": 390 }, "evidence": [ { "id": "F1NGS3", "url": "https://omabrowser.org/oma/group/F1NGS3/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "O60704-1", "protein_name": "Protein-tyrosine sulfotransferase 2", "gene_name": "TPST2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRLSVRRVLLAAGCALVLVLAVQLGQQVLECRAVLAGLRSPRGAMRPEQEELVMVGTNHVEYRYGKAMPLIFVGGVPRSGTTLMRAMLDAHPEVRCGEETRIIPRVLAMRQAWSKSGREKLRLDEAGVTDEVLDAAMQAFILEVIAKHGEPARVLCNKDPFTLKSSVYLSRLFPNSKFLLMVRDGRASVHSMITRKVTIAGFDLSSYRDCLTKWNKAIEVMYAQCMEVGKEKCLPVYYEQLVLHPRRSLKLILDFLGIAWSDAVLHHEDLIGKPGGVSLSKIERSTDQVIKPVNLEALSKWTGHIPGDVVRDMAQIAPMLAQLGYDPYANPPNYGNPDPFVINNTQRVLKGDYKTPANLKGYFQVNQNSTSSHLGSS", "length": 377 }, "evidence": [ { "id": "F1NGS3", "url": "https://omabrowser.org/oma/group/F1NGS3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "O88856-1", "protein_name": "Protein-tyrosine sulfotransferase 2", "gene_name": "Tpst2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRLSVRKVLLAAGCALALVLAVQLGQQVLECRAVLGGTRNPRRMRPEQEELVMLGADHVEYRYGKAMPLIFVGGVPRSGTTLMRAMLDAHPEVRCGEETRIIPRVLAMRQAWTKSGREKLRLDEAGVTDEVLDAAMQAFILEVIAKHGEPARVLCNKDPFTLKSSVYLARLFPNSKFLLMVRDGRASVHSMITRKVTIAGFDLSSYRDCLTKWNKAIEVMYAQCMEVGRDKCLPVYYEQLVLHPRRSLKRILDFLGIAWSDTVLHHEDLIGKPGGVSLSKIERSTDQVIKPVNLEALSKWTGHIPRDVVRDMAQIAPMLARLGYDPYANPPNYGNPDPIVINNTHRVLKGDYKTPANLKGYFQVNQNSTSPHLGSS", "length": 376 }, "evidence": [ { "id": "F1NGS3", "url": "https://omabrowser.org/oma/group/F1NGS3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q3SYY2-1", "protein_name": "Protein-tyrosine sulfotransferase 2", "gene_name": "TPST2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MRLSMRRALLAAGLALALVLAVHLGQRVLECQAVLGGPRGPRRTMRPEQEDLMMVGADHVEYRYGKAMPLIFVGGVPRSGTTLMRAMLDAHPEVRCGEETRIIPRVLAMRQAWSKSGREKLRLDEAGVTDEVLDAAMQAFILEVIAKHGEPARVLCNKDPFTLKSSVYLSRLFPNSKFLLMVRDGRASVHSMITRKVTIAGFDLSSYRDCLTKWNKAIEVMYAQCMEVGRDKCLPVYYEQLVLHPRRSLKVILDFLGIAWSDAVLHHEDLIGKPGGVSLSKIERSTDQVIKPVNLEALSKWTGHIPGDVLRDMAQIAPMLARLGYDPYANPPNYGNPDPIVINNTHRVLKGDYKTPANLKGYFQVNLNSTSSHLGSS", "length": 377 }, "evidence": [ { "id": "F1NGS3", "url": "https://omabrowser.org/oma/group/F1NGS3/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q5RJS8-1", "protein_name": "Protein-tyrosine sulfotransferase 2", "gene_name": "Tpst2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRLSVRKVLLAVGCALALVLAVQLGQQVLECRAVLGGVRSPRRMQPEQEELVMLGADHVEYRYGKTMPLIFVGGVPRSGTTLMRAMLDAHPEVRCGEETRIIPRVLAMRQAWTKSGREKLRLDEAGVTDEVLDAAMQAFILEVIAKHGEPARVLCNKDPFTLKSSVYLARLFPNSKFLLMVRDGRASVHSMITRKVTIAGFDLSSYRDCLTKWNKAIEVMYAQCMEVGRDKCLPVYYEQLVLHPRRSLKRILDFLGIAWSDTVLHHEDLIGKPGGVSLSKIERSTDQVIKPVNLEALSKWTGHIPRDVVRDMAQIAPMLARLGYDPYANPPNYGNPDPIVINNTHRVLKGDYKTPANLKGYFQVNQNSTSPHLGSS", "length": 376 }, "evidence": [ { "id": "F1NGS3", "url": "https://omabrowser.org/oma/group/F1NGS3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "F1NGS3", "url": "https://www.uniprot.org/uniprotkb/F1NGS3" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "F1NGS3", "url": "https://www.uniprot.org/uniprotkb/F1NGS3" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "F1NGS3", "url": "https://www.uniprot.org/uniprotkb/F1NGS3" } ], "pmid": "" }, { "name": "Golgi lumen", "id": "GO:0005796", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005796", "evidence": [ { "database": "UniProtKB", "id": "F1NGS3", "url": "https://www.uniprot.org/uniprotkb/F1NGS3" } ], "pmid": "" }, { "name": "trans-Golgi network", "id": "GO:0005802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005802", "evidence": [ { "database": "UniProtKB", "id": "F1NGS3", "url": "https://www.uniprot.org/uniprotkb/F1NGS3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "protein homodimerization activity", "id": "GO:0042803", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042803", "evidence": [ { "database": "UniProtKB", "id": "F1NGS3", "url": "https://www.uniprot.org/uniprotkb/F1NGS3" } ], "pmid": "" }, { "name": "protein-tyrosine sulfotransferase activity", "id": "GO:0008476", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008476", "evidence": [ { "database": "UniProtKB", "id": "F1NGS3", "url": "https://www.uniprot.org/uniprotkb/F1NGS3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 341, "end_pos": 343, "annotation": "n_glycosylation_sequon" }, { "start_pos": 366, "end_pos": 368, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "16801", "name": "", "equation": "L-tyrosyl-[protein] + 3'-phosphoadenylyl sulfate = O-sulfo-L-tyrosine-[protein] + adenosine 3',5'-bisphosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q5ZJI0-1", "A0A8V1ANA1-1", "F1NGS3-1" ], "evidence": [ { "id": "16801", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/16801" } ] }, { "id": "R-GGA-8954262", "name": "TPST1,2 transfer SO4(2-) from PAPS to PODXL2", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "Golgi lumen, Golgi membrane", "input_participant_list": [ "R-GGA-8954248" ], "output_participant_list": [ "R-GGA-8954273" ], "enzyme_list": [ "A0A8V1ANA1-1", "F1NGS3-1" ], "evidence": [ { "id": "R-GGA-8954262", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8954262" } ] } ], "reaction_participants": [ { "participant_id": "R-GGA-8954248", "participant_name": "PODXL2 [Golgi lumen]", "crossref": [ { "id": "A0A8V1A7U6", "database": "UniProt", "url": "" }, { "id": "ENSGALG00010028178", "database": "ENSEMBL", "url": "" }, { "id": "ENSGALP00010042026", "database": "ENSEMBL", "url": "" }, { "id": "ENSGALT00010068283", "database": "ENSEMBL", "url": "" } ] }, { "participant_id": "R-GGA-8954273", "participant_name": "PODXL2 [Golgi lumen]", "crossref": [ { "id": "ENSGALP00010042026", "database": "ENSEMBL", "url": "" }, { "id": "A0A8V1A7U6", "database": "UniProt", "url": "" }, { "id": "ENSGALT00010068283", "database": "ENSEMBL", "url": "" }, { "id": "ENSGALG00010028178", "database": "ENSEMBL", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A0A8V1ANA1", "gene_name": "TPST1", "activity": [ { "ec_number": "2.8.2.20", "activity": "L-tyrosyl-[protein] + 3'-phosphoadenylyl sulfate = O-sulfo-L-tyrosine-[protein] + adenosine 3',5'-bisphosphate + H(+).", "evidence": [ { "id": "A0A8V1ANA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANA1" } ] }, { "ec_number": "2.8.2.20", "activity": "", "evidence": [ { "id": "A0A8V1ANA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANA1" } ] } ] }, { "uniprot_ac": "F1NGS3", "gene_name": "TPST2", "activity": [ { "ec_number": "2.8.2.20", "activity": "L-tyrosyl-[protein] + 3'-phosphoadenylyl sulfate = O-sulfo-L-tyrosine-[protein] + adenosine 3',5'-bisphosphate + H(+).", "evidence": [ { "id": "F1NGS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NGS3" } ] }, { "ec_number": "2.8.2.20", "activity": "", "evidence": [ { "id": "F1NGS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NGS3" } ] } ] }, { "uniprot_ac": "Q5ZJI0", "gene_name": "TPST2", "activity": [ { "ec_number": "2.8.2.20", "activity": "L-tyrosyl-[protein] + 3'-phosphoadenylyl sulfate = O-sulfo-L-tyrosine-[protein] + adenosine 3',5'-bisphosphate + H(+).", "evidence": [ { "id": "Q5ZJI0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJI0" } ] }, { "ec_number": "2.8.2.20", "activity": "", "evidence": [ { "id": "Q5ZJI0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJI0" } ] } ] } ], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1NGS3-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 371, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1NGS3-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1NGS3" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.8.2.20", "ec_name": "L-tyrosyl-[protein] + 3'-phosphoadenylyl sulfate = O-sulfo-L-tyrosine-[protein] + adenosine 3',5'-bisphosphate + H(+).", "evidence": [ { "id": "2.8.2.20", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:2.8.2.20" }, { "id": "2.8.2.20", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.8.2.20" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 341, "end_pos": 343 }, { "start_pos": 366, "end_pos": 368 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1NH26-1", "uniprot_ac": "F1NH26", "uniprot_id": "F1NH26_CHICK", "mass": { "chemical_mass": 56287.0, "monoisotopic_mass": 56287.0 }, "refseq": { "ac": "XP_040525022", "name": "xaa-Pro aminopeptidase 3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040525022" }, "gene_names": [ { "name": "XPNPEP3", "type": "recommended", "evidence": [ { "id": "F1NH26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NH26" } ] }, { "name": "XPNPEP3", "type": "synonym", "evidence": [ { "id": "XP_040525022", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040525022" } ] } ], "protein_names": [ { "name": "Xaa-Pro aminopeptidase 3", "type": "recommended", "evidence": [ { "id": "F1NH26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NH26/entry#names_and_taxonomy" } ] }, { "name": "3.4.11.9", "type": "synonym", "evidence": [ { "id": "F1NH26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NH26/entry#names_and_taxonomy" } ] }, { "name": "Aminopeptidase P3", "type": "synonym", "evidence": [ { "id": "F1NH26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NH26/entry#names_and_taxonomy" } ] }, { "name": "xaa-Pro aminopeptidase 3", "type": "synonym", "evidence": [ { "id": "XP_040525022", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040525022" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040525022", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040525022" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NH26", "url": "https://www.uniprot.org/uniprotkb/F1NH26" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "XPNPEP3", "url": "https://www.uniprot.org/uniprotkb/F1NH26", "locus": { "chromosome": "1", "start_pos": 49930300, "end_pos": 49945354, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012910", "url": "https://www.ensembl.org/id/ENSGALG00010012910" } ] } } ], "crossref": [ { "id": "F1NH26", "url": "https://alphafold.ebi.ac.uk/entry/F1NH26", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000012003", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000012003", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd01087", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01087", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "418002", "url": "https://www.ncbi.nlm.nih.gov/gene/418002", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000994", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000994", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007865", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007865", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029149", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029149", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036005", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036005", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052433", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052433", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "DSYFWYL", "url": "https://omabrowser.org/oma/group/DSYFWYL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1NH26", "url": "https://www.orthodb.org/?gene=F1NH26", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR43226", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43226", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR43226:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43226:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00557", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00557", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF05195", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05195", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_040525022", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040525022", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1NH26", "url": "https://www.uniprot.org/uniprotkb/F1NH26", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NH26-1", "url": "https://www.uniprot.org/uniprotkb/F1NH26-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSRLPAVVRGWRGLAVCKSCILRRFSIQPAQQKKIPNRYLGQPSPFTHPHLLKPGEVTPGLSQVEYSLRRHKLMALIQKEAQGWEGLDHTVILLSNPTYYMSNDIPYVFHQDTNFLYLCGFQEPDSILVLQSLPGKALPSHKAILFVPRRDPSRELWDGPRSGTDGAVALTGVDEAYTIEEFGHLVAKLKGESNKVWYDVTKPVHKELHSDYMQPLAELKARSKNHIQSIRHLVQNLRLIKSPAEIERMKIAGRVTAEAFVETMFARKSPVDEAFLYAKFEFECRARGADILAYPPVVAGGNRSNTLHYVKNNQLIKDGELVLLDGGCESSCYVSDITRTWPVNGRFTKPQAELYQAVLDIQKSCLSLCSPGVSLENIYSLMLSLIGQKLKDLGILKSSITDSHFFKAVRRYCPHHVGHYLGMDVHDTPDISRSVPLQPGMVITIEPGLYIPEDDVSAPERFRGIGVRIEDDVVIADDSPLILSADCPKEIYDIEQICGRSS", "length": 502, "header": "tr|F1NH26-1|F1NH26_CHICK Isoform 1 of Xaa-Pro aminopeptidase 3 OS=Gallus gallus OX=9031 GN=XPNPEP3 PE=3 SV=2 CANONICAL=F1NH26-1" }, "isoforms": [ { "isoform_ac": "F1NH26-1", "url": "https://www.uniprot.org/uniprotkb/F1NH26/entry#F1NH26-1", "sequence": { "sequence": "MSRLPAVVRGWRGLAVCKSCILRRFSIQPAQQKKIPNRYLGQPSPFTHPHLLKPGEVTPGLSQVEYSLRRHKLMALIQKEAQGWEGLDHTVILLSNPTYYMSNDIPYVFHQDTNFLYLCGFQEPDSILVLQSLPGKALPSHKAILFVPRRDPSRELWDGPRSGTDGAVALTGVDEAYTIEEFGHLVAKLKGESNKVWYDVTKPVHKELHSDYMQPLAELKARSKNHIQSIRHLVQNLRLIKSPAEIERMKIAGRVTAEAFVETMFARKSPVDEAFLYAKFEFECRARGADILAYPPVVAGGNRSNTLHYVKNNQLIKDGELVLLDGGCESSCYVSDITRTWPVNGRFTKPQAELYQAVLDIQKSCLSLCSPGVSLENIYSLMLSLIGQKLKDLGILKSSITDSHFFKAVRRYCPHHVGHYLGMDVHDTPDISRSVPLQPGMVITIEPGLYIPEDDVSAPERFRGIGVRIEDDVVIADDSPLILSADCPKEIYDIEQICGRSS", "length": 502, "header": "tr|F1NH26-1|F1NH26_CHICK Isoform 1 of Xaa-Pro aminopeptidase 3 OS=Gallus gallus OX=9031 GN=XPNPEP3 PE=3 SV=2 CANONICAL=F1NH26-1" }, "locus": { "chromosome": "1", "start_pos": 49945335, "end_pos": 49930747, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030981.1", "url": "https://www.ensembl.org/id/ENSGALT00010030981.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018002.1", "url": "https://www.ensembl.org/id/ENSGALP00010018002.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 58, "start_aa": "Thr", "end_pos": 58, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr58", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0AAA9SIA3-1", "protein_name": "Xaa-Pro aminopeptidase 3", "gene_name": "XPNPEP3", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MRWLFSATRLVPAVASARSLSGCLSCSRRRYSLQPIPERRIPNRYLGQPSPFTHPHLLRPGEVTPGLSQVEYALRRHKLMSLIHKEAQEQSGTDHTVVLLSNPTYYMSNDIPYIFHQDNNFLYLCGFQEPDSILVLQSLPGKQLPAHKAMLFVPRRDPSRELWDGPRSGTDGAIALTGVDEAYTLEEFQHLVPKLKAETHTLWYDWMRPAHKQLHCDYMQQLAEVKARSKNKVRAVQQLVQRLRLIKSPAEIERMQVAGKLTSQAFIETMFASKAPVEEGFLYAKFEFECRARGADILAYPPVVAGGNRSNTLHYVKNNQLIKDGEMVLLDGGCESSCYVSDITRTWPVNGRFTAPQAELYEAVLEVQRDCLTLCCPGTSLENVYSMMLTLISQKLKELGITRNIKEKNPFKAARKYCPHHVGHYLGMDVHDTPDMPRSLPLQPGMVITVEPGIYIPEDDQDAPERFRGLGVRIEDDVVVTEASPLVLSADCPKEMKDIEQICSRAS", "length": 507 }, "evidence": [ { "id": "F1NH26", "url": "https://omabrowser.org/oma/group/F1NH26/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "B5DEQ3-1", "protein_name": "Xaa-Pro aminopeptidase 3", "gene_name": "Xpnpep3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLSLLSTPRLVPVIARLRGLSGCMSCLQRRYSLQPVPVKEIPNRYLGQPSPVTHPHLLRPGEVTPGLSQVEYALRRHKLMALVHKEAQGHSGTDHTVVVLSNPIHYMSNDIPYTFHQDNSFLYLCGFQEPDSILVLQSCSGKQLPSHKAMLFVPRRDPGRELWDGPRSGTDGAIALTGVDDAYPLEEFQHLLPKLRAETNMVWYDWMKPSHAQLHSDYMQPLTEAKATSKNKVRSVQHLIQHLRLIKSPAEIKRMQIAGKLTSEAFIETMFASKAPVDEAFLYAKFEFECRARGADILAYPPVVAGGNRSNTLHYVKNNQLIKDGEMVLLDGGCESSCYVSDITRTWPVNGRFTAPQAELYEAVLEIQKACLTLCSPGTSLENIYSMMLTLMGQKLKDLGIIKTSKESAFKAARKYCPHHVGHYLGMDVHDTPDMPRSLPLQPGMVITVEPGIYIPEGDTDAPEKFRGLGVRIEDDVVVTQDSPLILSADCPKEVNDIEQICSRTS", "length": 506 }, "evidence": [ { "id": "F1NH26", "url": "https://omabrowser.org/oma/group/F1NH26/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "B7ZMP1-1", "protein_name": "Xaa-Pro aminopeptidase 3", "gene_name": "Xpnpep3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPSLLSTPKLAPVLARLRGLSGCMSCLQRRYSLQPAPVKKIPNRYLGQPSPVTHPHLLRPGEVTPGLSQVEYALRRHKLMALVHKEAQGHSGTDHTVVVLSNPTYYMSNDIPYTFHQDNNFLYLCGFQEPDSILVLQSFSGKQLPSHKAMLFVPRRDPGRELWDGPRSGTDGAIALTGVDEAYPLEEFQHLLPKLRAETNMVWYDWMKPSHAQLHSDYMQPLTEAKARSKNKVRSVQQLIQRLRLVKSPSEIKRMQIAGKLTSEAFIETMFASKAPIDEAFLYAKFEFECRARGADILAYPPVVAGGNRSNTLHYVKNNQLIKDGEMVLLDGGCESSCYVSDITRTWPVNGRFTAPQAELYEAVLEIQRACLTLCSPGTSLENIYSMMLTLIGQKLKDLGITKTSKESAFKAARKYCPHHVGHYLGMDVHDTPDMPRSLPLQPGMVITVEPGIYIPEDDRDAPEKFRGLGVRIEDDVVVTQDSPLILSADCPKEMNDIEQICSRTS", "length": 506 }, "evidence": [ { "id": "F1NH26", "url": "https://omabrowser.org/oma/group/F1NH26/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F4HZG9-1", "protein_name": "Intermediate cleaving peptidase 55, mitochondrial", "gene_name": "ICP55", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MQFLARNLVRRVSRTQVVSRNAYSTQTVRDIGQPTPASHPHLMAEGEVTPGIRIEEYIGRRKKLVELLPENSLAIISSAPVKMMTDVVPYTFRQDADYLYLTGCQQPGGVAVLSDERGLCMFMPESTPKDIAWEGEVAGVDAASEVFKADQAYPISKLPEILSDMIRHSSKVFHNVQSASQRYTNLDDFQNSASLGKVKTLSSLTHELRLIKSPAELKLMRESASIACQGLLKTMLHSKGFPDEGILSAQVEYECRVRGAQRMAFNPVVGGGSNASVIHYSRNDQRIKDGDLVLMDMGCELHGYVSDLTRTWPPCGKFSSVQEELYDLILQTNKECIKQCKPGTTIRQLNTYSTELLCDGLMKMGILKSRRLYHQLNPTSIGHYLGMDVHDSSAVGYDRPLQPGFVITIEPGVYIPSSFDCPERFQGIGIRIEDDVLITETGYEVLTGSMPKEIKHIETLLNNHCHDNSARTSPVSLCKVKGLHTNRNPRRLF", "length": 493 }, "evidence": [ { "id": "F1NH26", "url": "https://omabrowser.org/oma/group/F1NH26/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "P40051-1", "protein_name": "Intermediate cleaving peptidase 55", "gene_name": "ICP55", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MLHRINPVRFSMQSCQRYFSKLVSPLEQHKSNTFTNRVRIPIEAGQPLHETRPFLIKSGELTPGISALEYYERRIRLAETLPPKSCVILAGNDIQFASGAVFYPFQQENDLFYLSGWNEPNSVMILEKPTDSLSDTIFHMLVPPKDAFAEKWEGFRSGVYGVQEIFNADESASINDLSKYLPKIINRNDFIYFDMLSTSNPSSSNFKHIKSLLDGSGNSNRSLNSIANKTIKPISKRIAEFRKIKSPQELRIMRRAGQISGRSFNQAFAKRFRNERTLDSFLHYKFISGGCDKDAYIPVVATGSNSLCIHYTRNDDVMFDDEMVLVDAAGSLGGYCADISRTWPNSGKFTDAQRDLYEAVLNVQRDCIKLCKASNNYSLHDIHEKSITLMKQELKNLGIDKVSGWNVEKLYPHYIGHNLGLDVHDVPKVSRYEPLKVGQVITIEPGLYIPNEESFPSYFRNVGIRIEDDIAIGEDTYTNLTVEAVKEIDDLENVMQNGLSTKFEEDQVAPL", "length": 511 }, "evidence": [ { "id": "F1NH26", "url": "https://omabrowser.org/oma/group/F1NH26/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q54T46-1", "protein_name": "Xaa-Pro aminopeptidase 3", "gene_name": "xpnpep3", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNNICKLNKFIISKSSSSLSSTSSKIKTNCLIKNAKMFSSSLNLNRFYSTNNTNNNKLKKPLSIGQATFETHPYLLDKNEITKGIKMKEFKDRREKLMKNFPIGSVVVIFTPPEPMMSYDIPWSFRQNTNFNYLTGFNEPEAVLVLVKTSELDHQSYLFVRERNEEKEKWDGARCGGENVKKYFGIDFGYNLTNRDIPILGKLLKSTTDGKLYCNTTPWNQLSNKLEPFLENIKFYTVESLLQQIRLIKSDAEIKMMLKSGEIAGTSFHETMKYTGTKSSSSSSSSSSSPLNEYQVSAYFEWCVKDKGAQRMSYPPVVAGGDNGHTLHYIQNNQLLNYCDLLLMDAGCEYWGYTSDITRTFPVSGKFTEAQSEVYQAVLDVNKKCIELCKPGETINSIHLKSVELIQAHLKRLGIINESNPNDYRLYYPHSIGHYLGMDTHDTLDFDYGVTLEPGMIITIEPGIYISKYDSNVPEKYRGISIRVEDDVVIPNLNNSPLVLTHLAPKEISEIESIMSNK", "length": 518 }, "evidence": [ { "id": "F1NH26", "url": "https://omabrowser.org/oma/group/F1NH26/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q9NQH7-1", "protein_name": "Xaa-Pro aminopeptidase 3", "gene_name": "XPNPEP3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPWLLSAPKLVPAVANVRGLSGCMLCSQRRYSLQPVPERRIPNRYLGQPSPFTHPHLLRPGEVTPGLSQVEYALRRHKLMSLIQKEAQGQSGTDQTVVVLSNPTYYMSNDIPYTFHQDNNFLYLCGFQEPDSILVLQSLPGKQLPSHKAILFVPRRDPSRELWDGPRSGTDGAIALTGVDEAYTLEEFQHLLPKMKAETNMVWYDWMRPSHAQLHSDYMQPLTEAKAKSKNKVRGVQQLIQRLRLIKSPAEIERMQIAGKLTSQAFIETMFTSKAPVEEAFLYAKFEFECRARGADILAYPPVVAGGNRSNTLHYVKNNQLIKDGEMVLLDGGCESSCYVSDITRTWPVNGRFTAPQAELYEAVLEIQRDCLALCFPGTSLENIYSMMLTLIGQKLKDLGIMKNIKENNAFKAARKYCPHHVGHYLGMDVHDTPDMPRSLPLQPGMVITIEPGIYIPEDDKDAPEKFRGLGVRIEDDVVVTQDSPLILSADCPKEMNDIEQICSQAS", "length": 507 }, "evidence": [ { "id": "F1NH26", "url": "https://omabrowser.org/oma/group/F1NH26/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9W5W7-1", "protein_name": "Aminopeptidase P N-terminal domain-containing protein", "gene_name": "Dmel\\CG9581", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MNILRRLDRLIAPTVRRSAAISTSLWPHRWMSQSTTISPGSPSSKSTVNAAEVRGVAQILRQQKGNLGQPTSVSHPHLIQPDELVPGVELTEIKERRSQLMQNIRAYARSFGGEFNGHSSSCHMLVLGAASKKYMSGKIPYVFRQNSDFYYLTGCLEPDAVLLLTIDEAQNVQSELFMRPKDPHAELWDGPRTGPELAVPLFGVTEAHPLSQLEAVLAKRAGALKPHIWFDQKSTDLPSLAENMLRLSGNQQRPLLPAYTFLEAMRLLKSRDEMQLMRRTCDIASRSFNEVMAETRPGQSEHHLFAAIDYKCRMRNASYLAYPPVVAAGKNATVIHYVANSQLLGQQDLVLMDAGCEYGGYTSDITRTWPASGVFTEPQRTLYDMLHQLQEEIIGNVMKPGGETLDQLFETTCYKLGKYLQEIGLVGKSFSEYKELVSQGYRFCPHHVSHYLGMDVHDTPHVPRNTRIVPGMVFTVEPGIYIGQDCGDVPPEFRGIGIRIEDDLLINENGHVEVLTEACVKDPRALQELCKQQQKNPGASSAEAF", "length": 545 }, "evidence": [ { "id": "F1NH26", "url": "https://omabrowser.org/oma/group/F1NH26/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "F1NH26", "url": "https://www.uniprot.org/uniprotkb/F1NH26" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F1NH26", "url": "https://www.uniprot.org/uniprotkb/F1NH26" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "F1NH26", "url": "https://www.uniprot.org/uniprotkb/F1NH26" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "manganese ion binding", "id": "GO:0030145", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030145", "evidence": [ { "database": "UniProtKB", "id": "F1NH26", "url": "https://www.uniprot.org/uniprotkb/F1NH26" } ], "pmid": "" }, { "name": "protein homodimerization activity", "id": "GO:0042803", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042803", "evidence": [ { "database": "UniProtKB", "id": "F1NH26", "url": "https://www.uniprot.org/uniprotkb/F1NH26" } ], "pmid": "" }, { "name": "aminopeptidase activity", "id": "GO:0004177", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004177", "evidence": [ { "database": "UniProtKB", "id": "F1NH26", "url": "https://www.uniprot.org/uniprotkb/F1NH26" } ], "pmid": "" }, { "name": "metalloaminopeptidase activity", "id": "GO:0070006", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070006", "evidence": [ { "database": "UniProtKB", "id": "F1NH26", "url": "https://www.uniprot.org/uniprotkb/F1NH26" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 302, "end_pos": 304, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1NH26-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 502, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1NH26-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1NH26" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1NH26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NH26" }, { "id": "SM01011", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM01011" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Aminopeptidase P N-terminal", "eco_id": "ECO_0000259", "start_pos": 61, "end_pos": 207, "start_aa": "Leu", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "3.4.11.9", "ec_name": "Release of any N-terminal amino acid, including proline, that is linked to proline, even from a dipeptide or tripeptide.", "evidence": [ { "id": "3.4.11.9", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=3.4.11.9" } ] } ], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 58 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 302, "end_pos": 304 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", 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"F1NH83_CHICK", "mass": { "chemical_mass": 36499.0, "monoisotopic_mass": 36499.0 }, "refseq": { "ac": "XP_015135675", "name": "hsp90 co-chaperone Cdc37-like 1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015135675" }, "gene_names": [ { "name": "CDC37L1", "type": "recommended", "evidence": [ { "id": "F1NH83", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NH83" } ] }, { "name": "CDC37L1", "type": "synonym", "evidence": [ { "id": "XP_015135675", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015135675" } ] } ], "protein_names": [ { "name": "Hsp90 co-chaperone Cdc37-like 1", "type": "recommended", "evidence": [ { "id": "F1NH83", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NH83/entry#names_and_taxonomy" } ] }, { "name": "hsp90 co-chaperone Cdc37-like 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015135675", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015135675" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052572.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015135675", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015135675" } ] }, { "annotation": "Co-chaperone that binds to numerous proteins and promotes their interaction with Hsp70 and Hsp90.", "evidence": [ { "database": "UniProtKB", "id": "F1NH83", "url": "https://www.uniprot.org/uniprotkb/F1NH83#function" }, { "database": "UniProtKB", "id": "ARBA00037145", "url": "https://www.uniprot.org/uniprotkb/ARBA00037145#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NH83", "url": "https://www.uniprot.org/uniprotkb/F1NH83" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CDC37L1", "url": "https://www.uniprot.org/uniprotkb/F1NH83", "locus": { "chromosome": "Z", "start_pos": 27872482, "end_pos": 27860093, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010011133", "url": "https://www.ensembl.org/id/ENSGALG00010011133" } ] } } ], "crossref": [ { "id": "F1NH83", "url": "https://alphafold.ebi.ac.uk/entry/F1NH83", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000014448", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000014448", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "426535", "url": "https://www.ncbi.nlm.nih.gov/gene/426535", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004918", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004918", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013874", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013874", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": 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"ENSGALP00010015187.1", "url": "https://www.ensembl.org/id/ENSGALP00010015187.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:426535", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:426535", "resource": "KEGG Pathway" }, { "id": "R-GGA-114608", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-114608", "resource": "Reactome", "description": "Platelet degranulation" } ], "orthologs": [ { "uniprot_canonical_ac": "A6H754-1", "protein_name": "Hsp90 co-chaperone Cdc37-like 1", "gene_name": "CDC37L1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": 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"MEQPWPPPGPWSLPRAGGEAEEESDLDVSPGSPRCLQLPGGGSQMYSHGIEMACQKQKEFVKSSVACKWNLAEAQQKLGSLALHNSESLDQEHAKAQTAVSELRQREEEWRQKEEALVQRERMCLWNMDAISKDVFNKSFINQDKRKETEDEDKSKSFMQKYEQKIRHFGMLSRWDDSQRFLSDNPYLVCEETAKYLILWCFHLEAEQKGALMEQIAHQAVVMQFIMEMAKNCNVDPRGCFRLFFQKAKAEEEGYFEAFKNELEAFKSRVRLYSQSPSFQPVTVQNHVPHSGVGSIGLLESLPQNPDYLQYSINTAPCSLNSVVHKEDDEPKMMDTV", "length": 337 }, "evidence": [ { "id": "F1NH83", "url": "https://omabrowser.org/oma/group/F1NH83/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q5XIC3-1", "protein_name": "Hsp90 co-chaperone Cdc37-like 1", "gene_name": "Cdc37l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEQPWPPPGPWSFPRTGGETEEESDLDVSPSSSHYSPVPDGGAQMYSHGIELACQRQKEFVKSSVACKWNLAEAQQKLGSLALHNSESLDQEHAKAQTAVSELRQREEEWRQKEEALVQRERTCLWNVDAISKDVFNKSFINQDKRKTEDEDKSQSFMQKYEQKIRHFGMLSRWDDSQRFLSDHPYLVCEETAKYLILWCFHLEAEQKGALMEQIAHQAVVMQFIMEMAKNCNVDPRGCFRLFFQKAKAEEEGYFEAFKNELEAFKARVRLYAQSQSFAPVTVENHAPHSGVGCIGSAEPLPQNPDSLQCCPPAPLCSVDSVVHKEDDDRMMDTV", "length": 335 }, "evidence": [ { "id": "F1NH83", "url": "https://omabrowser.org/oma/group/F1NH83/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q7L3B6-1", "protein_name": "Hsp90 co-chaperone Cdc37-like 1", "gene_name": "CDC37L1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEQPWPPPGPWSLPRAEGEAEEESDFDVFPSSPRCPQLPGGGAQMYSHGIELACQKQKEFVKSSVACKWNLAEAQQKLGSLALHNSESLDQEHAKAQTAVSELRQREEEWRQKEEALVQREKMCLWSTDAISKDVFNKSFINQDKRKDTEDEDKSESFMQKYEQKIRHFGMLSRWDDSQRFLSDHPYLVCEETAKYLILWCFHLEAEKKGALMEQIAHQAVVMQFIMEMAKNCNVDPRGCFRLFFQKAKAEEEGYFEAFKNELEAFKSRVRLYSQSQSFQPMTVQNHVPHSGVGSIGLLESLPQNPDYLQYSISTALCSLNSVVHKEDDEPKMMDTV", "length": 337 }, "evidence": [ { "id": "F1NH83", "url": "https://omabrowser.org/oma/group/F1NH83/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9CZP7-1", "protein_name": "Hsp90 co-chaperone Cdc37-like 1", "gene_name": "Cdc37l1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEQPWPPPGPWSFPRTGGETEEESDLDVSPSSSHYSPVPDGGAQMYSHGIELACQKQKEFVKSSVACKWNLAEAQQKLGSLALHNSESLDQEHAKAQTAVSELRQREEEWRQKEEALVQRERMCLWNMDAISKDVFNKSFINQDKRKTEEEDKSQSFMQKYEQKIRHFGMLSRWDDSQRFLSDHPHLVCEETAKYLILWCFHLEAEQKGALMEQIAHQAVVMQFIMEMAKNCNVDPRGCFRLFFQKAKAEEEGYFEAFKNELEAFKSRVRLYAQSQSLQPVTVQNHVPHSGVGCIGSLESLPQNPDSLQCCTPAPLCSVDSVVHKEDDDRMMDTV", "length": 335 }, "evidence": [ { "id": "F1NH83", "url": "https://omabrowser.org/oma/group/F1NH83/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1NH83", "url": "https://www.uniprot.org/uniprotkb/F1NH83" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F1NH83", "url": "https://www.uniprot.org/uniprotkb/F1NH83" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "unfolded protein binding", "id": "GO:0051082", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051082", "evidence": [ { "database": "UniProtKB", "id": "F1NH83", "url": "https://www.uniprot.org/uniprotkb/F1NH83" } ], "pmid": "" }, { "name": "protein-folding chaperone binding", "id": "GO:0051087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051087", "evidence": [ { "database": "UniProtKB", "id": "F1NH83", "url": "https://www.uniprot.org/uniprotkb/F1NH83" } ], "pmid": "" }, { "name": "heat shock protein binding", "id": "GO:0031072", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031072", "evidence": [ { "database": "UniProtKB", "id": "F1NH83", "url": "https://www.uniprot.org/uniprotkb/F1NH83" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "protein stabilization", "id": "GO:0050821", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050821", "evidence": [ { "database": "UniProtKB", "id": "F1NH83", "url": "https://www.uniprot.org/uniprotkb/F1NH83" } ], "pmid": "" }, { "name": "protein folding", "id": "GO:0006457", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006457", "evidence": [ { "database": "UniProtKB", "id": "F1NH83", "url": "https://www.uniprot.org/uniprotkb/F1NH83" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 125, "end_pos": 127, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1NH83-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 310, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1NH83-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1NH83" } ], 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"n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1NHV1-1", "uniprot_ac": "F1NHV1", "uniprot_id": "F1NHV1_CHICK", "mass": { "chemical_mass": 88971.0, "monoisotopic_mass": 88971.0 }, "refseq": {}, "gene_names": [ { "name": "DIEXF", "type": "recommended", "evidence": [ { "id": "F1NHV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NHV1" } ] } ], "protein_names": [ { "name": "U3 small nucleolar RNA-associated protein 25 homolog", "type": "recommended", "evidence": [ { "id": "F1NHV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NHV1/entry#names_and_taxonomy" } ] }, { "name": "Digestive organ expansion factor homolog", "type": "synonym", "evidence": [ { "id": "F1NHV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NHV1/entry#names_and_taxonomy" } ] }, { "name": "UTP25 small subunit processor component", "type": "synonym", "evidence": [ { "id": "F1NHV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NHV1/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Component of the ribosomal small subunit processome for the biogenesis of ribosomes, functions in pre-ribosomal RNA (pre-rRNA) processing. Essential for embryonic development in part through the regulation of p53 pathway. Controls the expansion growth of digestive organs and liver. Also involved in the sympathetic neuronal development. Mediates, with CAPN3, the proteasome-independent degradation of p53/TP53.", "evidence": [ { "database": "UniProtKB", "id": "F1NHV1", "url": "https://www.uniprot.org/uniprotkb/F1NHV1#function" }, { "database": "UniProtKB", "id": "ARBA00055734", "url": "https://www.uniprot.org/uniprotkb/ARBA00055734#function" }, { "database": "UniProtKB", "id": "A0A8V0ZFM0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFM0#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NHV1", "url": "https://www.uniprot.org/uniprotkb/F1NHV1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "DIEXF", "url": "https://www.uniprot.org/uniprotkb/F1NHV1", "locus": { "chromosome": "3", "start_pos": 22528027, "end_pos": 22544233, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010018969", "url": "https://www.ensembl.org/id/ENSGALG00010018969" } ] } } ], "crossref": [ { "id": "F1NHV1", "url": "https://alphafold.ebi.ac.uk/entry/F1NHV1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000009887", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000009887", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "421384", "url": "https://www.ncbi.nlm.nih.gov/gene/421384", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR010678", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010678", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR053939", "url": "https://www.ebi.ac.uk/interpro/entry/IPR053939", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR053940", "url": "https://www.ebi.ac.uk/interpro/entry/IPR053940", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:421384", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:421384", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QDRGDTF", "url": "https://omabrowser.org/oma/group/QDRGDTF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZFM0", "url": "https://www.orthodb.org/?gene=A0A8V0ZFM0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NHV1", "url": "https://www.orthodb.org/?gene=F1NHV1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12933", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12933", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12933:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12933:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF06862", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06862", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF22916", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22916", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-6791226", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6791226", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001026222", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026222", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZFM0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFM0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZFM0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFM0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NHV1", "url": "https://www.uniprot.org/uniprotkb/F1NHV1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NHV1-1", "url": "https://www.uniprot.org/uniprotkb/F1NHV1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGKRRGGRELARGLSKRQRKHLRQFGEQHPVCDRVSGRPEATQICELSDNSDKSSAESDSETEVEQVSVYHKLLATLKASPESESEEEEDESESEEAGESEAELDSEGSREPREAVGGEEEQNDVPEQEEEVAAKDPPEQALGQEEADGVETSCDPNRGAIEEFTDVKHEAEFSLETNFMEEESGDCDADKRESNSSQAFSEDPFKQHMDKELKEKEVEKISTLSKTSSQSKWPRLGQLTFSSTLEKHTTLKPDKEFSVKQLYLHKPLESTWPKVNKHYLSSASKPSDSFFTPLQRELFCIMNTYRDLFYPERNALTNGEEIRHAYCLHALNHILKANAQVLSNNAKKRDQKPGTDSDDYRDQGLTRPKVLMIVPFRECALRIVHIFISLLEVNEKRKIDVSNKKRFKGEFGSDPDEKPPNLKRPEDYEAVFAGNIDDHFRIGVAILQKSMRLYAPFYSSDIIIASPLGMRTIIGTEGEKKRDFDFLSSIEMLIIDQADIYLMQNWEHVLHLMRHINLLPLDSHGVDFSRVRMPNLNNWSKYYRQTLLFSALQDPQINAIFNKHCFNYVGQVAVRNVPLSGSISRVVVQLPHVFRRIEAENLTSVIDTRFQFFIDKVLPEYRDAIMSHTLIYVPSYFDYVRLRNYFKKEELNFTHICEYTKKAGICRARRSFLKGEKQFLLLTERFHFYKRYTIKGIRNLIFYELPTYSHFYSEICNMMKATDSGVDATWTCTVLYSKYDAQKLAAVVGIDRTAQMLQSKKNVHLFVTGENE", "length": 772, "header": "tr|F1NHV1-1|F1NHV1_CHICK Isoform 1 of U3 small nucleolar RNA-associated protein 25 homolog OS=Gallus gallus OX=9031 GN=DIEXF PE=3 SV=1 CANONICAL=F1NHV1-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZFM0-1", "url": "https://www.uniprot.org/uniprotkb/F1NHV1/entry#A0A8V0ZFM0-1", "sequence": { "sequence": "MGKRRGGRELARGLTLRGASARPRPLSSDNSDKSSAESDSETEVEQVSVYHKLLATLKASPESESEEEEDESESEEAGESEAELDSEGSREPREAVGGEEEQNDVPEQEEEVAAKDPPEQALGQEEADGVETSCDPNRGAIEEFTDVKHEAEFSLETNFMEEESGDCDADKRESNSSQAFSEDPFKQHMDKELKEKEVEKISTLSKTSSQSKWPRLGQLTFSSTLEKHTTLKPDKEFSVKQLYLHKPLESTWPKVNKHYLSSASKPSDSFFTPLQRELFCIMNTYRDLFYPERNALTNGEEIRHAYCLHALNHILKANAQVLSNNAKKRDQKPGTDSDDYRDQGLTRPKVLMIVPFRECALRIVHIFISLLEVNEKRKIDVSNKKRFKGEFGSDPDEKPPNLKRPEDYEAVFAGNIDDHFRIGVAILQKSMRLYAPFYSSDIIIASPLGMRTIIGTEGEKKRDFDFLSSIEMLIIDQADIYLMQNWEHVLHLMRHINLLPLDSHGVDFSRVRMPNLNNWSKYYRQTLLFSALQDPQINAIFNKHCFNYVGQVAVRNVPLSGSISRVVVQLPHVFRRIEAENLTSVIDTRFQFFIDKVLPEYRDAIMSHTLIYVPSYFDYVRLRNYFKKEELNFTHICEYTKKAGICRARRSFLKGEKQFLLLTERFHFYKRYTIKGIRNLIFYELPTYSHFYSEICNMMKATDSGVDATWTCTVLYSKYDAQKLAAVVGIDRTAQMLQSKKNVHLFVTGENE", "length": 752, "header": "tr|A0A8V0ZFM0-1|A0A8V0ZFM0_CHICK Computationally mapped isoform of U3 small nucleolar RNA-associated protein 25 homolog OS=Gallus gallus OX=9031 GN=DIEXF PE=3 SV=1 CANONICAL=F1NHV1-1" }, "locus": { "chromosome": "3", "start_pos": 22544182, "end_pos": 22530039, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010045933.1", "url": "https://www.ensembl.org/id/ENSGALT00010045933.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027366.1", "url": "https://www.ensembl.org/id/ENSGALP00010027366.1" } ] } }, { "isoform_ac": "F1NHV1-1", "url": "https://www.uniprot.org/uniprotkb/F1NHV1/entry#F1NHV1-1", "sequence": { "sequence": "MGKRRGGRELARGLSKRQRKHLRQFGEQHPVCDRVSGRPEATQICELSDNSDKSSAESDSETEVEQVSVYHKLLATLKASPESESEEEEDESESEEAGESEAELDSEGSREPREAVGGEEEQNDVPEQEEEVAAKDPPEQALGQEEADGVETSCDPNRGAIEEFTDVKHEAEFSLETNFMEEESGDCDADKRESNSSQAFSEDPFKQHMDKELKEKEVEKISTLSKTSSQSKWPRLGQLTFSSTLEKHTTLKPDKEFSVKQLYLHKPLESTWPKVNKHYLSSASKPSDSFFTPLQRELFCIMNTYRDLFYPERNALTNGEEIRHAYCLHALNHILKANAQVLSNNAKKRDQKPGTDSDDYRDQGLTRPKVLMIVPFRECALRIVHIFISLLEVNEKRKIDVSNKKRFKGEFGSDPDEKPPNLKRPEDYEAVFAGNIDDHFRIGVAILQKSMRLYAPFYSSDIIIASPLGMRTIIGTEGEKKRDFDFLSSIEMLIIDQADIYLMQNWEHVLHLMRHINLLPLDSHGVDFSRVRMPNLNNWSKYYRQTLLFSALQDPQINAIFNKHCFNYVGQVAVRNVPLSGSISRVVVQLPHVFRRIEAENLTSVIDTRFQFFIDKVLPEYRDAIMSHTLIYVPSYFDYVRLRNYFKKEELNFTHICEYTKKAGICRARRSFLKGEKQFLLLTERFHFYKRYTIKGIRNLIFYELPTYSHFYSEICNMMKATDSGVDATWTCTVLYSKYDAQKLAAVVGIDRTAQMLQSKKNVHLFVTGENE", "length": 772, "header": "tr|F1NHV1-1|F1NHV1_CHICK Isoform 1 of U3 small nucleolar RNA-associated protein 25 homolog OS=Gallus gallus OX=9031 GN=DIEXF PE=3 SV=1 CANONICAL=F1NHV1-1" }, "locus": { "chromosome": "3", "start_pos": 22544182, "end_pos": 22530039, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010045944.1", "url": "https://www.ensembl.org/id/ENSGALT00010045944.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027372.1", "url": "https://www.ensembl.org/id/ENSGALP00010027372.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:421384", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:421384", "resource": "KEGG Pathway" }, { "id": "R-GGA-6791226", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6791226", "resource": "Reactome", "description": "Major pathway of rRNA processing in the nucleolus and cytosol" } ], "orthologs": [ { "uniprot_canonical_ac": "P40498-1", "protein_name": "U3 small nucleolar RNA-associated protein 25", "gene_name": "UTP25", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSDSSVREKNDNFRGYRKRGRQELRKIKRSSARTEGGSTETLEDVAEDIDHRSDEDEVSDVDSGDDFDIEDEEGKKEKVYDALLTILKSEHPEPKRRRREADESNKAPAEVGEDEHENTEHGPVDDQLEIENGLLGNHEDDNDDDSSGDEKDIDSEDEQDPFESHFNQVPEKFVDKLSNAFKTKSVKYKSVKGSLSDSESYIYAKPVVIGEEALVESPYRSSSIYSYFLKQRLKVQNGLLDKKTDPLTALQKKLVDPMFQYKDILYEYDSYEKDEDEYRDLYALHVLNHIYKTRDRILKNNQRLQDNPDTEHLDQGFTRPKVLIVVPTREVAYRVVDKIISKSGIDQVDKKGKFYDQFRDDSLPPKSKPKSFQHIFRGNTNDFFVVGLKFTRKAIKLYSNFYQSDIIVCSPLGIQMILENTDKKKRQDDFLSSIELMVIDQLHSIEYQNISHIFTIFDHLNKIPDQQHEADFSRIRMWYINEQAKLFRQTMVFTKYISPAANSLINGRCRNMAGRWKNHKVIGSENSSIGQSGLKIRQIFQRFDIIGNSIIEEPDYRFKFFTSVIIPGIVKSTGYEDGILIYIPDYTDFIRIRNYMKEKTTILFGDINEYSSQRQLNANRSLFQQGRLKVMLYTERLHHYRRYEIKGVKSVVFYKPPNNPEFYNEVVRFIGKNAFLGNTDLNISTVRCIYSKLDGLSLERIVGTKRAAVLSHAQKEIYEFK", "length": 721 }, "evidence": [ { "id": "F1NHV1", "url": "https://omabrowser.org/oma/group/F1NHV1/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q5M9G7-1", "protein_name": "U3 small nucleolar RNA-associated protein 25 homolog", "gene_name": "Utp25", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGKRRSRGRSQLLSTMTKKQKKHLRDFGEEHPFYDRVSKKEVKPQICQLSESSDSSHSESESESEQEHVSGYHRLLATLKNISEEEEEEEEEEEEEEEDKEEVDDSAVGDSEMNGEDGGEDVRVEETAESSETQDHMSLADNSKGKDGEEPPGVSQKSSEEFTDVKHESLFSLETNFLEEESGGSYSQRTSQDPFQHHINKELQEKEIQAAASSPAATQQLKWPVLGHLVFSSKFQKMETFKPPKDIDLKSLHLQKPLESTWAKTNSQFLSGPGPQKSSSCFTPLQKELFLIMNSYRDLFYPERTALKNGEEVRHVYCLHAINHVLKANAQVLANNSRRRTQKLGVGDDDDFRDQGLTRPKVLIVVPFREAALRVVQLFISLLEGDSKKKIIVSNKKRFQGEYGSDPEERPPNLKRPEDYEAVFVGNIDDHFRIGVAILQRSIRLYAPFYSSDILIASPLGLRTIIGGEGEKKRDFDFLSSIELLIIDQADIYLMQNWEHVLHLMNHMNLLPLDSHGVNFSRVRMWSLNNWSKYYRQTLLFGALQDAQINSVFNKHCVNAQGQVAVRNVPMTGSISHVLVQLPHVFQRMEAQDLASVIDARFHFFINKILPQYRDAVMSHTLIYVPSYFDFVRLRNYFKKEELNFTHICEYTQRSGVSRARHFFLQGEKQFLLLTERFHFYKRYTIKGIRNLIFYELPTYAHFYSEVCNMLRATSRGEEATWTCTVLYSKYDAQRLAAVVGVERAAQMLQSPKSVHLFITGEK", "length": 763 }, "evidence": [ { "id": "F1NHV1", "url": "https://omabrowser.org/oma/group/F1NHV1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q68CQ4-1", "protein_name": "U3 small nucleolar RNA-associated protein 25 homolog", "gene_name": "UTP25", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGKRGSRSQSQLLNTLTKKQKKHLRDFGEEHPFYDRVSRKEAKPQICQLSESSDSSDSESDSESEPQQVSGYHRLLATLKNVSEEEEEDEEEEEEEDSIVDDAEMNDEDGGSDVSVEEEMAAESTESPENVALSADPEGKEDGEEPPGTSQTSPEEFTDAKHESLFSLETNFLEEESGDNSSLKASQDPFLQHVNKELKEKAIQAVATNPKTTHELKWPILGQLFFSSKFQKLETFKPPKDIDLKSLHLQKPLESTWTKTNSQFLSGPQKSSSPFTPLQKELFLIMNSYRDLFYPERTALKNGEEIRHVYCLHVINHILKANAQVLGNNSRRRSQKFGVGDDDDFRDQGLTRPKVLIVVPFREAALRVVQLFISLLEGDSKKKIIVSNKKRFQGEYGSDPEERPPNLKRPEDYEAVFVGNIDDHFRIGVAILQRSIRLYAPFYSSDILIASPLGLRTIIGGEGEKKRDFDFLSSIELLIIDQADIYLMQNWEHVLHLMNHMNLLPLDSHGVDFSRVRMWSLNNWSKYYRQTLLFGALQDAQINSVFNKYCVNMQGQVAVRNVPMTGSISHVLVQLPHVFQRMEAENLASVIDARFNFFVNKILPQYRDAVMSHTLIYIPSYFDFVRLRNYFKKEELNFTHICEYTQKSGVSRARHFFLQGEKQFLLFTERFHFYKRYTIKGIRNLIFYELPTYPHFYSEICNMLRATNRGEEATWTCTVLYSKYDAQRLAAVVGVERAAQMLQSNKNVHLFITGEK", "length": 756 }, "evidence": [ { "id": "F1NHV1", "url": "https://omabrowser.org/oma/group/F1NHV1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q6PEH4-1", "protein_name": "U3 small nucleolar RNA-associated protein 25 homolog", "gene_name": "utp25", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MGKRRRGKQEIDNLTKKQKKHLKEFGEQHPFHDKVVERPEKTQILRLPDSPQRPEPDSEDDSDAEQPSAYQKLLSTMIQGDEDDVESEDEESEEEDNEEEAEVEGDSEEEVEDTDEEDGNDAEEVLEDKVEETSDKLQKKHPEKTNGDVEENEEAEMEGEFTDKKNEAAFCLETNMPAEGEENTAQQEQDEDMFVKHQEIELSEEEVGRISQGSKVKTQVKWAKLGVLQCMCPLERFPAIGQASSAPLPPIHKTLEANWHLLNLPFGAATDVTELQKEMLGLMGTYRDLYLANLSPLKEAKEVRSAYCLHALNHVLKANSRVLRNNAKLKESKNGDEDFRDQGLTRPKVLILVPFRDGALRVVQTFMTLLEPKGKKTDASNKKRFKEEYGEETDEKPPNLQRPDDYHAVFSGNIDDHFRIGMSILRHSMRLYAPFYSSDIIIASPLGLRTVLGAEGEKKRDHDFLSSIELLIVDQADVFLMQNWEHLLHVLEHLNLQPLDSHGVDFSRVRMWNLNNWAAYYRQTLVFSAIQEPQITNILTKHCHNYRGQVCSKTIPKIGSICQVLVQLPHVFQMFHSDSFMDQDARFQFFVDKILPQYRDSVMSHTFIYVPSYFDFVRLRNYLKKEDVSFANISEYSQRSEVSRARHYFQKGEKQFLLFSERFHFYKRYTIKGIHNLIFYGLPTYPHFYSEVCNMLQAGVREGGASVSFTCTALYSRYDVHRLAAITGADRAAQMLQSKKTTHLFITGEEKST", "length": 753 }, "evidence": [ { "id": "F1NHV1", "url": "https://omabrowser.org/oma/group/F1NHV1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q8BTT6-1", "protein_name": "U3 small nucleolar RNA-associated protein 25 homolog", "gene_name": "Utp25", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGKRRNRGRSQMLSTMTKKQKKHLRDFGEEHPFYDRVSKKEAKPQICQLPESSDSSHSESESESEQEHVSGYHRLLATLKNVSEEEEEEEEEEEEEEEEEEEEEEEEEDDSAVGDAEMNEEAGSEDGSVGEAAVSEAAEEAAETQEHMSLADNSKEKDGEEPPGVSQKSSEEFTDVKHESLFSLETNFLEEDSGGSCSQRPSQDPFQQHVNKELKEKEIQAAASSPPATQQLKWPVLGHLVFSSKFQKTETFKPPKDIDLKLLHLQKPLESTWAKTNSQFLSGPQKSNSSFTPLQKELFLIMNSYRDLFYPERTALKNGEEVRHVYCLHAINHVLKANAQVLANNSRRRSQKLGVGEDDDFRDQGLTRPKVLIVVPFREAALRVVQLFISLLEGDSKKKIIVSNKKRFQGEYGSDPEERPPNLKRPEDYEAVFVGNIDDHFRIGVAILQRSIRLYAPFYSSDILIASPLGLRTIIGGEGEKKRDFDFLSSVELLIIDQADIYLMQNWEHVLHLMNHMNLLPLDSHGVDFSRVRMWSLNNWSKYYRQTLLFGALQDAQINSVFNKHCINAQGQVAVRNVPMTGSISHVLVQLPHVFQRMEAQDLSSVIDARFHFFINKILPQYRDAVMSHTLIYVPSYFDFVRLRNYFKKEELNFTHICEYTQKSGISRARHFFLQGEKQFLLLTERFHFYKRYTIKGIRNLIFYELPTYPHFYSEVCNMLRATSRGEEATWTCTVLYSKYDAQRLAAVVGVERAAQMLQSPKNVHLFVTGEK", "length": 772 }, "evidence": [ { "id": "F1NHV1", "url": "https://omabrowser.org/oma/group/F1NHV1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8H1E7-1", "protein_name": "Protein NUCLEOLAR FACTOR 1", "gene_name": "NOF1", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MAPNATGVLKRHRSHEKFDKKRDTKKHKHVEKTIVSNPSTDSPEESSIEAESEAMVYREPTQYQNLLVSLGSSNKVVADMNKRRQREEEGKSDTEEDEDDEDEDEEENSGSDDLSSTDGEDDKSQGDDQETLGGLTDDTQEDNDNQSEEEDPDDYETDEEVHELSTNGQSFVDASSSISAFSEHLSHKLSSEEVETLPKGKWKFKWESPAFDMPNCKWKGTSENFLDGIQSDAPYGLKPKLYNHWLQLYKKCGGKDLDSSKRRKFFSICNSYLDILHSNKKPFYHCGSDEDSSAMDAYLMHSLNHIFKTRDLVKKNESKIAKHRETSEEEILSDDGFLDQGFTRPKVLILLPLRSIAFRVVKRLIQLTPESQRVNVEHLDRFNDEFGCEEDTDDCDGEKTTSKNGNSIKQKSSKPSDWQALFGANNNDDEFMLGIKHTRKSIRLYGDFYSSDIIVASPLKLHMAIGAAEENKERDVDYLSSIEVLVIDHADIISMQNWSFLATVVDYLNRLPTKQHGTNVMRIRPLYLDGHARFYRQSIILSSYLTPEMNSLFGRHCLNYKGKMKMACEYKGVLEKVLLPVRQIYERFDAASITQVDDARLEYFTKKIFPKIKDSVQGGVMIFIHSYFEFVRLRNFLNTQNTSFCLLGDYAKNADISRAREQFFVGSRKIMLYTERAYFYKRYKIRGIKNLILYSLPERKEFYPEIMNMLEEGSHDMMSTALFSRFDMLQLERIVGSTSAKRMITSEKNMFAFC", "length": 754 }, "evidence": [ { "id": "F1NHV1", "url": "https://omabrowser.org/oma/group/F1NHV1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9W1G1-1", "protein_name": "Digestive organ expansion factor homolog", "gene_name": "Dmel\\CG3735", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MKQKHSKNRAKPYKKPTPARRNERFSKNYSFIQRSKQMEESHRRERMPTAPKQEYEPVAELLPEIQDDVDETEFYKKLITGVNNIPTSDILRSKAEKEEDHVIPVPRKIKPKKEKRSEQLGVDLEIYNSFSKRFDFELSTDNINDLIARKDVKTIKRNWSALGNVRFDIPRLTEDFKEPDCSEPKDIASTEDLQKLEVKASICANAKLPLTALQSQLFYIANNYQDIYYPHRTHGNAEDIRYVYCLHALNHMLKVRSLILRNNEKVSALAKSQKMSPNEISIPESFRDQGLKRMKVVFVVPFRESALRIVNILGDLLFGSQDDQARKTSIANYERFLGDYSGNTIYFPKTNPKPMDYEQTFSGNTDDNFKLGIRFTKKTMSLFSDMNASDMLIASPLGLRMLVTDKESDFDFLNSIELLIIDQAELFLAQNWENLLHSLDHLHLQPQKLPDTNCQRVRTWCLSGASSFYRQTLFFSSHELPEFRAVFNSKCNNYQGKVRDSNLVEHGDIRNVLTPIHQVFRLINCSSVETTFDDRFQYFVKNIMPQFSKPGFSHCMLYVPSYFDYVRIRNHFKTEMVSFVQINEYTKKEKISRARDIFFHSGASVLLYSERAHFFRRTRIKGIRNLIMYQPPNFPHFYSEIINLMLKTNQNPRDGFGDEMSVSILYTKYDLLSLSNIVGSENAAKLTSGQKDSYLFSTKT", "length": 700 }, "evidence": [ { "id": "F1NHV1", "url": "https://omabrowser.org/oma/group/F1NHV1/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "protein localization to nucleolus", "id": "GO:1902570", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902570", "evidence": [ { "database": "UniProtKB", "id": "F1NHV1", "url": "https://www.uniprot.org/uniprotkb/F1NHV1" } ], "pmid": "" }, { "name": "protein catabolic process", "id": "GO:0030163", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030163", "evidence": [ { "database": "UniProtKB", "id": "F1NHV1", "url": "https://www.uniprot.org/uniprotkb/F1NHV1" } ], "pmid": "" }, { "name": "protein destabilization", "id": "GO:0031648", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031648", "evidence": [ { "database": "UniProtKB", "id": "F1NHV1", "url": "https://www.uniprot.org/uniprotkb/F1NHV1" } ], "pmid": "" }, { "name": "embryonic organ development", "id": "GO:0048568", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048568", "evidence": [ { "database": "UniProtKB", "id": "F1NHV1", "url": "https://www.uniprot.org/uniprotkb/F1NHV1" } ], "pmid": "" }, { "name": "maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "id": "GO:0000462", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000462", "evidence": [ { "database": "UniProtKB", "id": "F1NHV1", "url": "https://www.uniprot.org/uniprotkb/F1NHV1" } ], "pmid": "" }, { "name": "rRNA processing", "id": "GO:0006364", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006364", "evidence": [ { "database": "UniProtKB", "id": "F1NHV1", "url": "https://www.uniprot.org/uniprotkb/F1NHV1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "F1NHV1", "url": "https://www.uniprot.org/uniprotkb/F1NHV1" } ], "pmid": "" }, { "name": "small-subunit processome", "id": "GO:0032040", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032040", "evidence": [ { "database": "UniProtKB", "id": "F1NHV1", "url": "https://www.uniprot.org/uniprotkb/F1NHV1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "rRNA binding", "id": "GO:0019843", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019843", "evidence": [ { "database": "UniProtKB", "id": "F1NHV1", "url": "https://www.uniprot.org/uniprotkb/F1NHV1" } ], "pmid": "" }, { "name": "U3 snoRNA binding", "id": "GO:0034511", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034511", "evidence": [ { "database": "UniProtKB", "id": "F1NHV1", "url": "https://www.uniprot.org/uniprotkb/F1NHV1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 195, "end_pos": 197, "annotation": "n_glycosylation_sequon" }, { "start_pos": 538, "end_pos": 540, "annotation": "n_glycosylation_sequon" }, { "start_pos": 601, "end_pos": 603, "annotation": "n_glycosylation_sequon" }, { "start_pos": 652, "end_pos": 654, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1NHV1-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 772, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1NHV1-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1NHV1" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1NHV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NHV1" }, { "id": "PF06862", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06862" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "UTP25 C-terminal", "eco_id": "ECO_0000259", "start_pos": 582, "end_pos": 766, "start_aa": "Ser", "end_aa": "Phe", "glycosite_overlap": "" }, { "evidence": [ { "id": "F1NHV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NHV1" }, { "id": "PF22916", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22916" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "UTP25 NTP hydrolase-like", "eco_id": "ECO_0000259", "start_pos": 305, "end_pos": 572, "start_aa": "Tyr", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 195, "end_pos": 197 }, { "start_pos": 538, "end_pos": 540 }, { "start_pos": 601, "end_pos": 603 }, { "start_pos": 652, "end_pos": 654 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1NHZ7-1", "uniprot_ac": "F1NHZ7", "uniprot_id": "F1NHZ7_CHICK", "mass": { "chemical_mass": 55993.0, "monoisotopic_mass": 55993.0 }, "refseq": { "ac": "NP_001376386", "name": "proton-coupled zinc antiporter SLC30A1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376386" }, "gene_names": [ { "name": "SLC30A1", "type": "recommended", "evidence": [ { "id": "F1NHZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NHZ7" } ] }, { "name": "SLC30A1", "type": "synonym", "evidence": [ { "id": "NP_001376386", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376386" } ] } ], "protein_names": [ { "name": "Solute carrier family 30 member 1", "type": "synonym", "evidence": [ { "id": "F1NHZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NHZ7/entry#names_and_taxonomy" } ] }, { "name": "proton-coupled zinc antiporter SLC30A1", "type": "synonym", "evidence": [ { "id": "NP_001376386", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376386" } ] }, { "name": "solute carrier family 30 (zinc transporter), member 1", "type": "synonym", "evidence": [ { "id": "NP_001376386", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376386" } ] }, { "name": "zinc transporter 1", "type": "synonym", "evidence": [ { "id": "NP_001376386", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376386" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: LC492895.1, SRR13267659.115407.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000062.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001376386", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376386" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NHZ7", "url": "https://www.uniprot.org/uniprotkb/F1NHZ7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SLC30A1", "url": "https://www.uniprot.org/uniprotkb/F1NHZ7", "locus": { "chromosome": "3", "start_pos": 21890980, "end_pos": 21882587, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010020625", "url": "https://www.ensembl.org/id/ENSGALG00010020625" } ] } } ], "crossref": [ { "id": "F1NHZ7", "url": "https://alphafold.ebi.ac.uk/entry/F1NHZ7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000009858", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000009858", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "421377", "url": "https://www.ncbi.nlm.nih.gov/gene/421377", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002524", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002524", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027469", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027469", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027470", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027470", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR058533", "url": "https://www.ebi.ac.uk/interpro/entry/IPR058533", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "CLFHQHG", "url": "https://omabrowser.org/oma/group/CLFHQHG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1NHZ7", "url": "https://www.orthodb.org/?gene=F1NHZ7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45820", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45820", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45820:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45820:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01545", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01545", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16916", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16916", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-435368", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-435368", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001376386", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376386", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1NHZ7", "url": "https://www.uniprot.org/uniprotkb/F1NHZ7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NHZ7-1", "url": "https://www.uniprot.org/uniprotkb/F1NHZ7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MCGGMAAEGPGGPRWWQNRRARLLCMLALTFLFFVVEVVVSRVTSSLAMLSDSFHMLSDVMALVVALVAVRFAQRTRATKKNTFGWVRAEVMGALVNAVFLTALCFTILLEAIERFTEPHEIQQPLVVIAVGVAGLVINLLGLCLFNHHGVGGHGHSHGHGHAHGGGARLPRGGGKAEQTPGDGEAALHREETSTLVENCSSSNGVSQEKLGDMKDDTTDLQVNGNAGHYPLDVEEVEEDSSAQLNMRGVFLHVFGDALGSVIVVVNALLFYGLWNPCPKDGPCFNPCVNSHCVENATLSQPLGSANKSEQESITVAGPCWLLYLDPVLCLIMVCILLYTTYPLLRESALILLQTVPKQIDVHSLNSKLRTLEGVEAVHELHIWQLAGSRIIGTAHIKCPDPSTYMMVAKRIKEIFHDEGIHATTIQPEFASVGSESGRGKCEFPCRTQCALKQCCGTVEDNTGKKTEKSSSLSISCSEVVIEFPHNKTRRTKSESVPAVKLEANTDQNEQFESSL", "length": 516, "header": "tr|F1NHZ7-1|F1NHZ7_CHICK Isoform 1 of Solute carrier family 30 member 1 OS=Gallus gallus OX=9031 GN=SLC30A1 PE=1 SV=3 CANONICAL=F1NHZ7-1" }, "isoforms": [ { "isoform_ac": "F1NHZ7-1", "url": "https://www.uniprot.org/uniprotkb/F1NHZ7/entry#F1NHZ7-1", "sequence": { "sequence": "MCGGMAAEGPGGPRWWQNRRARLLCMLALTFLFFVVEVVVSRVTSSLAMLSDSFHMLSDVMALVVALVAVRFAQRTRATKKNTFGWVRAEVMGALVNAVFLTALCFTILLEAIERFTEPHEIQQPLVVIAVGVAGLVINLLGLCLFNHHGVGGHGHSHGHGHAHGGGARLPRGGGKAEQTPGDGEAALHREETSTLVENCSSSNGVSQEKLGDMKDDTTDLQVNGNAGHYPLDVEEVEEDSSAQLNMRGVFLHVFGDALGSVIVVVNALLFYGLWNPCPKDGPCFNPCVNSHCVENATLSQPLGSANKSEQESITVAGPCWLLYLDPVLCLIMVCILLYTTYPLLRESALILLQTVPKQIDVHSLNSKLRTLEGVEAVHELHIWQLAGSRIIGTAHIKCPDPSTYMMVAKRIKEIFHDEGIHATTIQPEFASVGSESGRGKCEFPCRTQCALKQCCGTVEDNTGKKTEKSSSLSISCSEVVIEFPHNKTRRTKSESVPAVKLEANTDQNEQFESSL", "length": 516, "header": "tr|F1NHZ7-1|F1NHZ7_CHICK Isoform 1 of Solute carrier family 30 member 1 OS=Gallus gallus OX=9031 GN=SLC30A1 PE=1 SV=3 CANONICAL=F1NHZ7-1" }, "locus": { "chromosome": "3", "start_pos": 21887591, "end_pos": 21882754, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049782.1", "url": "https://www.ensembl.org/id/ENSGALT00010049782.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029417.1", "url": "https://www.ensembl.org/id/ENSGALP00010029417.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-435368", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-435368", "resource": "Reactome", "description": "Zinc efflux and compartmentalization by the SLC30 family" } ], "orthologs": [ { "uniprot_canonical_ac": "E1BN60-1", "protein_name": "Solute carrier family 30 member 1", "gene_name": "SLC30A1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGCWGRNRGRLLCMLLLTFMFMVLEVVVSRVTTSLAMLSDSFHMLSDVLALVVALVAERFARRTHATQKNTFGWIRAEVMGALVNAIFLTGLCFAILLEAIERFIEPHEMQQPLVVFGVGVAGLVVNVLGLCLFHHHSGFGDDSSHSHSHGGHSHGLPKGARSKSSRAGGSDNAVTPGEQGPDQEETNILVANSSNSNGLKLDQTDPEKSRNDAMEVQVNGNLIREPEEVELEEDEDKTGQLNMRGVFLHVFGDALGSVIVVVNALVFYFNWKGCPEGEICVNPCIPDPCKAFVELVNSTQATVQEAGPCWVLYLDPTLCVVMVCILLYTTYPLLKESALILLQTVPKQIDIKNLIKELRNVEGVEEVHELHVWQLAGSRIIATAHIKCEDPASYMQVAKIIKDVFHNHGIHATTIQPEFASVGSKSSVVPCELACRTQCALKQCCGTRPQAQSGKDAEKAPSVSISCLELSDNLEKQPKRTKVENIPAVVIEIKKMPNKQPESSL", "length": 506 }, "evidence": [ { "id": "F1NHZ7", "url": "https://omabrowser.org/oma/group/F1NHZ7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P20107-1", "protein_name": "Vacuolar zinc transporter ZRC1", "gene_name": "ZRC1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MITGKELRIISLLTLDTVFFLLEITIGYMSHSLALIADSFHMLNDIISLLVALWAVDVAKNRGPDAKYTYGWKRAEILGALINAVFLIALCFSIMIEALQRLIEPQEIQNPRLVLYVGVAGLISNVVGLFLFHDHGSDSLHSHSHGSVESGNNDLDIESNATHSHSHASLPNDNLAIDEDAISSPGPSGQIGEVLPQSVVNRLSNESQPLLNHDDHDHSHESKKPGHRSLNMHGVFLHVLGDALGNIGVIAAALFIWKTEYSWRYYSDPIVSLIITIIIFSSALPLSRRASRILLQATPSTISADQIQREILAVPGVIAVHDFHVWNLTESIYIASIHVQIDCAPDKFMSSAKLIRKIFHQHGIHSATVQPEFVSGDVNEDIRRRFSIIAGGSPSSSQEAFDSHGNTEHGRKKRSPTAYGATTASSNCIVDDAVNCNTSNCL", "length": 442 }, "evidence": [ { "id": "F1NHZ7", "url": "https://omabrowser.org/oma/group/F1NHZ7/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q60738-1", "protein_name": "Proton-coupled zinc antiporter SLC30A1", "gene_name": "Slc30a1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGCWGRNRGRLLCMLLLTFMFMVLEVVVSRVTASLAMLSDSFHMLSDVLALVVALVAERFARRTHATQKNTFGWIRAEVMGALVNAIFLTGLCFAILLEAVERFIEPHEMQQPLVVLSVGVAGLLVNVLGLCLFHHHSGEGQGAGHGHSHGHGHGHLAKGARKAGRAGVEAGAPPGRAPDQEETNTLVANTSNSNGLKADQAEPEKLRSDDPVDVQVNGNLIQESDNLEAEDNRAGQLNMRGVFLHVLGDALGSVIVVVNALVFYFNWKGCTEDDFCTNPCFPDPCKSSVEIINSTQAPMRDAGPCWVLYLDPTLCIIMVCILLYTTYPLLKESALILLQTVPKQIDIKHLVKELRDVDGVEEVHELHVWQLAGSRIIATAHIKCEDPASYMQVAKTIKDVFHNHGIHATTIQPEFASVGSKSSVLPCELACRTQCALKQCCGTRPQVHSGKDAEKAPTVSISCLELSENLEKKARRTKAEGSLPAVVIEIKNVPNKQPESSL", "length": 503 }, "evidence": [ { "id": "F1NHZ7", "url": "https://omabrowser.org/oma/group/F1NHZ7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q62720-1", "protein_name": "Proton-coupled zinc antiporter SLC30A1", "gene_name": "Slc30a1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGCWGRNRGRLLCMLLLTFMFMVLEVVVSRVTASLAMLSDSFHMLSDVLALVVALVAERFARRTHATQKNTFGWIRAEVMGALVNAIFLTGLCFAILLEAVERFIEPHEMQQPLVVLSVGVAGLLVNVLGLCLFHHHSGEGQGAGHGHSHGHGHGHLAKGARKAGRAGGEAGAPPGRAPDQEPDQEETNTLVANTSNSNGLKADQAEPEKLRSDDPVDVQVNGNLIQESDSLESEDNRAGQLNMRGVFLHVLGDALGSVIVVVNALVFYFSWKGCTEDDFCVNPCFPDPCKSSVELMNSTQAPMHEAGPCWVLYLDPTLCIIMVCILLYTTYPLLKESALILLQTVPKQIDIKHLVKELRDVEGVEEVHELHVWQLAGSRIIATAHIKCEDPASYMQVAKTIKDVFHNHGIHATTIQPEFASVGSKSSVVPCELACRTQCALKQCCGTRPQVHSGKEAEKAPTVSISCLELSENLEKKPRRTKAEGSVPAVVIEIKNVPNKQPESSL", "length": 507 }, "evidence": [ { "id": "F1NHZ7", "url": "https://omabrowser.org/oma/group/F1NHZ7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9Y6M5-1", "protein_name": "Proton-coupled zinc antiporter SLC30A1", "gene_name": "SLC30A1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGCWGRNRGRLLCMLALTFMFMVLEVVVSRVTSSLAMLSDSFHMLSDVLALVVALVAERFARRTHATQKNTFGWIRAEVMGALVNAIFLTGLCFAILLEAIERFIEPHEMQQPLVVLGVGVAGLLVNVLGLCLFHHHSGFSQDSGHGHSHGGHGHGHGLPKGPRVKSTRPGSSDINVAPGEQGPDQEETNTLVANTSNSNGLKLDPADPENPRSGDTVEVQVNGNLVREPDHMELEEDRAGQLNMRGVFLHVLGDALGSVIVVVNALVFYFSWKGCSEGDFCVNPCFPDPCKAFVEIINSTHASVYEAGPCWVLYLDPTLCVVMVCILLYTTYPLLKESALILLQTVPKQIDIRNLIKELRNVEGVEEVHELHVWQLAGSRIIATAHIKCEDPTSYMEVAKTIKDVFHNHGIHATTIQPEFASVGSKSSVVPCELACRTQCALKQCCGTLPQAPSGKDAEKTPAVSISCLELSNNLEKKPRRTKAENIPAVVIEIKNMPNKQPESSL", "length": 507 }, "evidence": [ { "id": "F1NHZ7", "url": "https://omabrowser.org/oma/group/F1NHZ7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 9, "go_terms": [ { "name": "detoxification of zinc ion", "id": "GO:0010312", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010312", "evidence": [ { "database": "UniProtKB", "id": "F1NHZ7", "url": "https://www.uniprot.org/uniprotkb/F1NHZ7" } ], "pmid": "" }, { "name": "zinc ion transmembrane transport", "id": "GO:0071577", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071577", "evidence": [ { "database": "UniProtKB", "id": "F1NHZ7", "url": "https://www.uniprot.org/uniprotkb/F1NHZ7" } ], "pmid": "" }, { "name": "negative regulation of calcium ion import", "id": "GO:0090281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090281", "evidence": [ { "database": "UniProtKB", "id": "F1NHZ7", "url": "https://www.uniprot.org/uniprotkb/F1NHZ7" } ], "pmid": "" }, { "name": "intracellular calcium ion homeostasis", "id": "GO:0006874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006874", "evidence": [ { "database": "UniProtKB", "id": "F1NHZ7", "url": "https://www.uniprot.org/uniprotkb/F1NHZ7" } ], "pmid": "" }, { "name": "defense response to bacterium", "id": "GO:0042742", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042742", "evidence": [ { "database": "UniProtKB", "id": "F1NHZ7", "url": "https://www.uniprot.org/uniprotkb/F1NHZ7" } ], "pmid": "" }, { "name": "copper ion transport", "id": "GO:0006825", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006825", "evidence": [ { "database": "UniProtKB", "id": "F1NHZ7", "url": "https://www.uniprot.org/uniprotkb/F1NHZ7" } ], "pmid": "" }, { "name": "intracellular zinc ion homeostasis", "id": "GO:0006882", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006882", "evidence": [ { "database": "UniProtKB", "id": "F1NHZ7", "url": "https://www.uniprot.org/uniprotkb/F1NHZ7" } ], "pmid": "" }, { "name": "negative regulation of zinc ion transmembrane import", "id": "GO:0071584", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071584", "evidence": [ { "database": "UniProtKB", "id": "F1NHZ7", "url": "https://www.uniprot.org/uniprotkb/F1NHZ7" } ], "pmid": "" }, { "name": "zinc ion import into organelle", "id": "GO:0062111", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0062111", "evidence": [ { "database": "UniProtKB", "id": "F1NHZ7", "url": "https://www.uniprot.org/uniprotkb/F1NHZ7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "zinc ion transmembrane transporter activity", "id": "GO:0005385", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005385", "evidence": [ { "database": "UniProtKB", "id": "F1NHZ7", "url": "https://www.uniprot.org/uniprotkb/F1NHZ7" } ], "pmid": "" }, { "name": "calcium channel inhibitor activity", "id": "GO:0019855", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019855", "evidence": [ { "database": "UniProtKB", "id": "F1NHZ7", "url": "https://www.uniprot.org/uniprotkb/F1NHZ7" } ], "pmid": "" }, { "name": "calcium:monoatomic cation antiporter activity", "id": "GO:0015368", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015368", "evidence": [ { "database": "UniProtKB", "id": "F1NHZ7", "url": "https://www.uniprot.org/uniprotkb/F1NHZ7" } ], "pmid": "" }, { "name": "zinc:proton antiporter activity", "id": "GO:0140826", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140826", "evidence": [ { "database": "UniProtKB", "id": "F1NHZ7", "url": "https://www.uniprot.org/uniprotkb/F1NHZ7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "F1NHZ7", "url": "https://www.uniprot.org/uniprotkb/F1NHZ7" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "F1NHZ7", "url": "https://www.uniprot.org/uniprotkb/F1NHZ7" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "F1NHZ7", "url": "https://www.uniprot.org/uniprotkb/F1NHZ7" } ], "pmid": "" }, { "name": "basolateral plasma membrane", "id": "GO:0016323", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016323", "evidence": [ { "database": "UniProtKB", "id": "F1NHZ7", "url": "https://www.uniprot.org/uniprotkb/F1NHZ7" } ], "pmid": "" }, { "name": "nuclear membrane", "id": "GO:0031965", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031965", "evidence": [ { "database": "UniProtKB", "id": "F1NHZ7", "url": "https://www.uniprot.org/uniprotkb/F1NHZ7" } ], "pmid": "" }, { "name": "cytoplasmic vesicle membrane", "id": "GO:0030659", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030659", "evidence": [ { "database": "UniProtKB", "id": "F1NHZ7", "url": "https://www.uniprot.org/uniprotkb/F1NHZ7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 199, "end_pos": 201, "annotation": "n_glycosylation_sequon" }, { "start_pos": 296, "end_pos": 298, "annotation": "n_glycosylation_sequon" }, { "start_pos": 307, "end_pos": 309, "annotation": "n_glycosylation_sequon" }, { "start_pos": 487, "end_pos": 489, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1NHZ7-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 516, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1NHZ7-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1NHZ7" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1NHZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NHZ7" }, { "id": "PF16916", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16916" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Cation efflux protein cytoplasmic", "eco_id": "ECO_0000259", "start_pos": 357, "end_pos": 429, "start_aa": "Pro", "end_aa": "Glu", "glycosite_overlap": "" }, { "evidence": [ { "id": "F1NHZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NHZ7" }, { "id": "PF01545", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01545" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Cation efflux protein transmembrane", "eco_id": "ECO_0000259", "start_pos": 24, "end_pos": 272, "start_aa": "Leu", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 199, "end_pos": 201 }, { "start_pos": 296, "end_pos": 298 }, { "start_pos": 307, "end_pos": 309 }, { "start_pos": 487, "end_pos": 489 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1NI04-1", "uniprot_ac": "F1NI04", "uniprot_id": "F1NI04_CHICK", "mass": { "chemical_mass": 60636.0, "monoisotopic_mass": 60636.0 }, "refseq": { "ac": "NP_001186488", "name": "N-acetylglucosamine-6-sulfatase precursor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186488" }, "gene_names": [ { "name": "GNS", "type": "recommended", "evidence": [ { "id": "F1NI04", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NI04" } ] }, { "name": "GNS", "type": "synonym", "evidence": [ { "id": "NP_001186488", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186488" } ] }, { "name": "N-acetylglucosamine-6-sulfatase", "type": "synonym", "evidence": [ { "id": "NP_001186488", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186488" } ] } ], "protein_names": [ { "name": "N-acetylglucosamine-6-sulfatase", "type": "recommended", "evidence": [ { "id": "F1NI04", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NI04/entry#names_and_taxonomy" } ] }, { "name": "3.1.6.14", "type": "synonym", "evidence": [ { "id": "F1NI04", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NI04/entry#names_and_taxonomy" } ] }, { "name": "Glucosamine-6-sulfatase", "type": "synonym", "evidence": [ { "id": "F1NI04", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NI04/entry#names_and_taxonomy" } ] }, { "name": "N-acetylglucosamine-6-sulfatase precursor", "type": "synonym", "evidence": [ { "id": "NP_001186488", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186488" } ] }, { "name": "glucosamine (N-acetyl)-6-sulfatase (Sanfilippo disease IIID)", "type": "synonym", "evidence": [ { "id": "NP_001186488", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186488" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: SRR13267649.2115.1, SRR12888542.213083.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA103992290, SAMEA103992323 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000012.1. On Dec 10, 2010 this sequence version replaced XP_416070.2. Sequence Note: This RefSeq record was created from transcripts from different strains and genomic sequence data because no single transcript from the same strain was available for the full length of the gene. The extent of this transcript is supported by transcript alignments and orthologous data.", "evidence": [ { "database": "RefSeq", "id": "NP_001186488", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186488" } ] }, { "annotation": "Hydrolyzes 6-sulfate groups in N-acetyl-d-glucosaminide units of heparin sulfate and keratan sulfate.", "evidence": [ { "database": "UniProtKB", "id": "F1NI04", "url": "https://www.uniprot.org/uniprotkb/F1NI04#function" }, { "database": "UniProtKB", "id": "ARBA00057082", "url": "https://www.uniprot.org/uniprotkb/ARBA00057082#function" }, { "database": "UniProtKB", "id": "A0A8V0YC89", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC89#function" }, { "database": "UniProtKB", "id": "A0A8V0YHR9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHR9#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NI04", "url": "https://www.uniprot.org/uniprotkb/F1NI04" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "GNS", "url": "https://www.uniprot.org/uniprotkb/F1NI04", "locus": { "chromosome": "1", "start_pos": 33900118, "end_pos": 33920687, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013150", "url": "https://www.ensembl.org/id/ENSGALG00010013150" } ] } } ], "crossref": [ { "id": "F1NI04", "url": "https://alphafold.ebi.ac.uk/entry/F1NI04", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000009856", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000009856", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd16147", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16147", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "417829", "url": "https://www.ncbi.nlm.nih.gov/gene/417829", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000917", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000917", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012251", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012251", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017850", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017850", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024607", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024607", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:417829", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417829", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WCHGEHE", "url": "https://omabrowser.org/oma/group/WCHGEHE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YC89", "url": "https://www.orthodb.org/?gene=A0A8V0YC89", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YHR9", "url": "https://www.orthodb.org/?gene=A0A8V0YHR9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NI04", "url": "https://www.orthodb.org/?gene=F1NI04", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR43108", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43108", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR43108:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43108:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00884", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00884", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-2022857", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2022857", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-6798695", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6798695", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001186488", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186488", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YC89", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC89", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YC89-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC89-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHR9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHR9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHR9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHR9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NI04", "url": "https://www.uniprot.org/uniprotkb/F1NI04", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NI04-1", "url": "https://www.uniprot.org/uniprotkb/F1NI04-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSRSALAALARGLALAALLVLSPAQAARQRPNVVLILTDDQDVFLGGMTPMKKTNALIAQMGVTFSNAYVPSALCCPSRASILTGKYPHNHHVVNNTLEGNCSSKLWQKIQEPNTFPALLKSMCGYQTFFAGKYLNEYGAEDAGGVSHVPPGWSFWYALEKNSKYYNYTLSVNGKARRHGENYSVDYLTDVLANMSLDFLEYKSNFEPFFMMISTPAPHSPWTAAPQYKNDFLNVSAPRNSNFNIHGKNKHWLIRQAKTPMTNSSIQFLDDAYRKRWQTLLSVDDLVEKLVKKLEIHGELDNTYIFYTSDNGFHTGQFSLPIDKRQLYEFDIKVPLLVRGPGIKPNQTNKMLVANIDLGPTILDIAGYDLNKTQMDGMSLLPLLRGDKNVTWRSDFLVEYQGEGYNGSDPTCPGLGPGVTHCFPDCVCEDSYNNTYACVRTMSTSWDLQYCEFDDREVFVEVYNLTADPHQINNIAKTIDQEILEKMNYRLMMLQSCSGATCRTPGVFDPGYRFDPRLMFSNHGVRARRFSTRSLPSI", "length": 538, "header": "tr|F1NI04-1|F1NI04_CHICK Isoform 1 of N-acetylglucosamine-6-sulfatase OS=Gallus gallus OX=9031 GN=GNS PE=1 SV=2 CANONICAL=F1NI04-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YC89-1", "url": "https://www.uniprot.org/uniprotkb/F1NI04/entry#A0A8V0YC89-1", "sequence": { "sequence": "MSRSALAALARGLALAALLVLSPAQAARQRPNVVLILTDDQDVFLGGMTPMKKTNALIAQMGVTFSNAYVPSALCCPSRASILTGKYPHNHHVVNNTLEGNCSSKLWQKIQEPNTFPALLKSMCGYQTFFAGKYLNEYGAEDAGGVSHVPPGWSFWYALEKNSKYYNYTLSVNGKARRHGENYSVDYLTDANMSLDFLEYKSNFEPFFMMISTPAPHSPWTAAPQYKNDFLNVSAPRNSNFNIHGKNKHWLIRQAKTPMTNSSIQFLDDAYRKRWQTLLSVDDLVEKLVKKLEIHGELDNTYIFYTSDNGFHTGQFSLPIDKRQLYEFDIKVPLLVRGPGIKPNQTNKMLVANIDLGPTILDIAGYDLNKTQMDGMSLLPLLRGDKNVTWRSDFLVEYQGEGYNGSDPTCPGLGPGVTHCFPDCVCEDSYNNTYACVRTMSTSWDLQYCEFDDREVFVEVYNLTADPHQINNIAKTIDQEILEKMNYRLMMLQSCSGATCRTPGVFDPGYRFDPRLMFSNHGVRARRFSTRSLPSI", "length": 536, "header": "tr|A0A8V0YC89-1|A0A8V0YC89_CHICK Computationally mapped isoform of N-acetylglucosamine-6-sulfatase OS=Gallus gallus OX=9031 GN=GNS PE=1 SV=1 CANONICAL=F1NI04-1" }, "locus": { "chromosome": "1", "start_pos": 33920549, "end_pos": 33903657, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031520.1", "url": "https://www.ensembl.org/id/ENSGALT00010031520.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018410.1", "url": "https://www.ensembl.org/id/ENSGALP00010018410.1" } ] } }, { "isoform_ac": "A0A8V0YHR9-1", "url": "https://www.uniprot.org/uniprotkb/F1NI04/entry#A0A8V0YHR9-1", "sequence": { "sequence": "MSRSALAARQRPNVVLILTDDQDVFLGGMTPMKKTNALIAQMGVTFSNAYVPSALCCPSRASILTGKYPHNHHVVNNTLEGNCSSKLWQKIQEPNTFPALLKSMCGYQTFFAGKYLNEYGAEDAGGVSHVPPGWSFWYALEKNSKYYNYTLSVNGKARRHGENYSVDYLTDVLANMSLDFLEYKSNFEPFFMMISTPAPHSPWTAAPQYKNDFLNVSAPRNSNFNIHGKNKHWLIRQAKTPMTNSSIQFLDDAYRKRWQTLLSVDDLVEKLVKKLEIHGELDNTYIFYTSDNGFHTGQFSLPIDKRQLYEFDIKVPLLVRGPGIKPNQTNKMLVANIDLGPTILDIAGYDLNKTQMDGMSLLPLLRGDKNVTWRSDFLVEYQGEGYNGSDPTCPGLGPGVTHCFPDCVCEDSYNNTYACVRTMSTSWDLQYCEFDDREVFVEVYNLTADPHQINNIAKTIDQEILEKMNYRLMMLQSCSGATCRTPGVFDPGYRFDPRLMFSNHGVRARRFSTRSLPSI", "length": 519, "header": "tr|A0A8V0YHR9-1|A0A8V0YHR9_CHICK Computationally mapped isoform of N-acetylglucosamine-6-sulfatase OS=Gallus gallus OX=9031 GN=GNS PE=1 SV=1 CANONICAL=F1NI04-1" }, "locus": { "chromosome": "1", "start_pos": 33920549, "end_pos": 33903657, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031524.1", "url": "https://www.ensembl.org/id/ENSGALT00010031524.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018414.1", "url": "https://www.ensembl.org/id/ENSGALP00010018414.1" } ] } }, { "isoform_ac": "F1NI04-1", "url": "https://www.uniprot.org/uniprotkb/F1NI04/entry#F1NI04-1", "sequence": { "sequence": "MSRSALAALARGLALAALLVLSPAQAARQRPNVVLILTDDQDVFLGGMTPMKKTNALIAQMGVTFSNAYVPSALCCPSRASILTGKYPHNHHVVNNTLEGNCSSKLWQKIQEPNTFPALLKSMCGYQTFFAGKYLNEYGAEDAGGVSHVPPGWSFWYALEKNSKYYNYTLSVNGKARRHGENYSVDYLTDVLANMSLDFLEYKSNFEPFFMMISTPAPHSPWTAAPQYKNDFLNVSAPRNSNFNIHGKNKHWLIRQAKTPMTNSSIQFLDDAYRKRWQTLLSVDDLVEKLVKKLEIHGELDNTYIFYTSDNGFHTGQFSLPIDKRQLYEFDIKVPLLVRGPGIKPNQTNKMLVANIDLGPTILDIAGYDLNKTQMDGMSLLPLLRGDKNVTWRSDFLVEYQGEGYNGSDPTCPGLGPGVTHCFPDCVCEDSYNNTYACVRTMSTSWDLQYCEFDDREVFVEVYNLTADPHQINNIAKTIDQEILEKMNYRLMMLQSCSGATCRTPGVFDPGYRFDPRLMFSNHGVRARRFSTRSLPSI", "length": 538, "header": "tr|F1NI04-1|F1NI04_CHICK Isoform 1 of N-acetylglucosamine-6-sulfatase OS=Gallus gallus OX=9031 GN=GNS PE=1 SV=2 CANONICAL=F1NI04-1" }, "locus": { "chromosome": "1", "start_pos": 33920549, "end_pos": 33903657, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031530.1", "url": "https://www.ensembl.org/id/ENSGALT00010031530.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018418.1", "url": "https://www.ensembl.org/id/ENSGALP00010018418.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "gga:417829", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417829", "resource": "KEGG Pathway" }, { "id": "R-GGA-2022857", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2022857", "resource": "Reactome", "description": "Keratan sulfate degradation" }, { "id": "R-GGA-6798695", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6798695", "resource": "Reactome", "description": "Neutrophil degranulation" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287A524-1", "protein_name": "N-acetylglucosamine-6-sulfatase", "gene_name": "GNS", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRLLPLASGGPRRGSPRHLPSCSPALLLLLCGCLGVSRVAAADSRRPNVVLLLADDQDEVLGGMTPLKKTKALIGEMGMTFSSAYVPSALCCPSRASILTGKYPHNHHVVNNTLEGNCSSKSWQKIEEPNTFPAILRSVCGYQTFFAGKYLNEYGAPDAGGLAHVPLGWSYWYALEKNSKYYNYTLSINGKARKHGENYSVDYLTDVLANVSLDFLDYKSNSEPFFMMISTPAPHSPWTAAPQYQNTFQNVFAPRNKNFNIHGTNKHWLIRQAKTPMTNSSIQFLDNAFRKRWQTLLSVDDLVEKLVKRLEFNGELNNTYIFYTSDNGYHTGQFSLPIDKRQLYEFDIKVPLLVRGPGIKPNQTTKMLVANIDLGPTILDIAGYNLNKTQMDGMSFLPILKGASNLTWRSDVLVEYQGEGRNVTDPTCPSLSPGVSQCFPDCVCEDAYNNTYACVRTMSHLWNLQYCEFDDQEVFVEVYNLTADPHQINNIAKSIDPELLGKMNYRLMMLQSCSGPTCRTPGVFDPGREEGRMRS", "length": 535 }, "evidence": [ { "id": "F1NI04", "url": "https://omabrowser.org/oma/group/F1NI04/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0ABI0NJH4-1", "protein_name": "N-acetylglucosamine-6-sulfatase", "gene_name": "GNS", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MRLLSLAPDRPRRGGPRHLTSGSPALLLLLLGGCLGVSGAAKSSRRPNVVLLLADDQDEVLGGMTPLKKTKALIGEMGMTFSSAYVPSALCCPSRASILTGKYPHNHHVVNNTLEGNCSSKSWQKIQEPNTFPAILRSMCGYQTFFAGKYLNEYGAPDAGGLGHVPLGWSYWYALEKNSKYYNYTLSINGKARKHGENYSVDYLTDVLANVSLDFLDYKSNSEPFFMMISTPAPHSPWTAAPQYQNAFQNVFAPRNKNFNIHGTNKHWLIRQAKTPMTNSSIQFLDNAFRKRWQTLLSVDDLVEKLVKRLEFNGELNNTYIFYTSDNGYHTGQFSLPIDKRQLYEFDIKVPLLVRGPGIKPNQTSKMLVANIDLGPTILDIAGYSLNKTQMDGMSFLPILKGASNLTWRSDVLVEYQGEGRNVTDPTCPSLSPGVSQCFPDCVCEDAYNNTYACVRTMSERWNLQYCEFDDQEVFVEVYNLTADPHQLNNIAKSIDPELLGKMNYRLMMLQSCSGPTCRTPGVFDPGYRFDPRLMFSNHGSVRTRRFSKHLL", "length": 552 }, "evidence": [ { "id": "F1NI04", "url": "https://omabrowser.org/oma/group/F1NI04/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P15586-1", "protein_name": "N-acetylglucosamine-6-sulfatase", "gene_name": "GNS", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRLLPLAPGRLRRGSPRHLPSCSPALLLLVLGGCLGVFGVAAGTRRPNVVLLLTDDQDEVLGGMTPLKKTKALIGEMGMTFSSAYVPSALCCPSRASILTGKYPHNHHVVNNTLEGNCSSKSWQKIQEPNTFPAILRSMCGYQTFFAGKYLNEYGAPDAGGLEHVPLGWSYWYALEKNSKYYNYTLSINGKARKHGENYSVDYLTDVLANVSLDFLDYKSNFEPFFMMIATPAPHSPWTAAPQYQKAFQNVFAPRNKNFNIHGTNKHWLIRQAKTPMTNSSIQFLDNAFRKRWQTLLSVDDLVEKLVKRLEFTGELNNTYIFYTSDNGYHTGQFSLPIDKRQLYEFDIKVPLLVRGPGIKPNQTSKMLVANIDLGPTILDIAGYDLNKTQMDGMSLLPILRGASNLTWRSDVLVEYQGEGRNVTDPTCPSLSPGVSQCFPDCVCEDAYNNTYACVRTMSALWNLQYCEFDDQEVFVEVYNLTADPDQITNIAKTIDPELLGKMNYRLMMLQSCSGPTCRTPGVFDPGYRFDPRLMFSNRGSVRTRRFSKHLL", "length": 552 }, "evidence": [ { "id": "F1NI04", "url": "https://omabrowser.org/oma/group/F1NI04/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8BFR4-1", "protein_name": "N-acetylglucosamine-6-sulfatase", "gene_name": "Gns", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRLPSAAGPRPGRPRRLPALLLLPLLGGCLGLVGAARRPNVLLLLTDDQDAELGGMTPLKKTKALIGEKGMTFSSAYVPSALCCPSRASILTGKYPHNHHVVNNTLEGNCSSKAWQKIQEPYTFPAILKSVCGYQTFFAGKYLNEYGAPDAGGLEHIPLGWSYWYALEKNSKYYNYTLSINGKARKHGENYSVDYLTDVLANLSLDFLDYKSNSEPFFMMISTPAPHSPWTAAPQYQKAFQNVIAPRNKNFNIHGTNKHWLIRQAKTPMTNSSIRFLDDAFRRRWQTLLSVDDLVEKLVKRLDSTGELDNTYIFYTSDNGYHTGQFSLPIDKRQLYEFDIKVPLLVRGPGIKPNQTSKMLVSNIDLGPTILDLAGYDLNKTQMDGMSLLPILKGDRNLTWRSDVLVEYQGEGRNVTDPTCPSLSPGVSQCFPDCVCEDAYNNTYACVRTLSSLWNLQYCEFDDQEVFVEVYNITADPDQITNIAKSIDPELLGKMNYRLMMLQSCSGPTCRTPGVFDPGYRFDLRLMFNSHGSVRTRRFSKHPL", "length": 544 }, "evidence": [ { "id": "F1NI04", "url": "https://omabrowser.org/oma/group/F1NI04/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "N-acetylglucosamine-6-sulfatase activity", "id": "GO:0008449", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008449", "evidence": [ { "database": "UniProtKB", "id": "F1NI04", "url": "https://www.uniprot.org/uniprotkb/F1NI04" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "F1NI04", "url": "https://www.uniprot.org/uniprotkb/F1NI04" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "lysosome", "id": "GO:0005764", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005764", "evidence": [ { "database": "UniProtKB", "id": "F1NI04", "url": "https://www.uniprot.org/uniprotkb/F1NI04" } ], "pmid": "" }, { "name": "azurophil granule", "id": "GO:0042582", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042582", "evidence": [ { "database": "UniProtKB", "id": "F1NI04", "url": "https://www.uniprot.org/uniprotkb/F1NI04" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "glycosaminoglycan metabolic process", "id": "GO:0030203", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030203", "evidence": [ { "database": "UniProtKB", "id": "F1NI04", "url": "https://www.uniprot.org/uniprotkb/F1NI04" } ], "pmid": "" }, { "name": "heparan sulfate proteoglycan catabolic process", "id": "GO:0030200", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030200", "evidence": [ { "database": "UniProtKB", "id": "F1NI04", "url": "https://www.uniprot.org/uniprotkb/F1NI04" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 101, "end_pos": 103, "annotation": "n_glycosylation_sequon" }, { "start_pos": 167, "end_pos": 169, "annotation": "n_glycosylation_sequon" }, { "start_pos": 182, "end_pos": 184, "annotation": "n_glycosylation_sequon" }, { "start_pos": 194, "end_pos": 196, "annotation": "n_glycosylation_sequon" }, { "start_pos": 234, "end_pos": 236, "annotation": "n_glycosylation_sequon" }, { "start_pos": 263, "end_pos": 265, "annotation": "n_glycosylation_sequon" }, { "start_pos": 346, "end_pos": 348, "annotation": "n_glycosylation_sequon" }, { "start_pos": 371, "end_pos": 373, "annotation": "n_glycosylation_sequon" }, { "start_pos": 389, "end_pos": 391, "annotation": "n_glycosylation_sequon" }, { "start_pos": 406, "end_pos": 408, "annotation": "n_glycosylation_sequon" }, { "start_pos": 433, "end_pos": 435, "annotation": "n_glycosylation_sequon" }, { "start_pos": 464, "end_pos": 466, "annotation": "n_glycosylation_sequon" }, { "start_pos": 95, "end_pos": 97, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-GGA-1638032", "name": "GNS:Ca2+ cleaves sulfate from GlcNAc-6-sulfate units of keratan sulfate", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "lysosomal lumen", "input_participant_list": [ "R-ALL-2104995" ], "output_participant_list": [ "R-ALL-1606845" ], "enzyme_list": [ "F1NI04-1" ], "evidence": [ { "id": "R-GGA-1638032", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1638032" } ] }, { "id": "R-GGA-6798751", "name": "Exocytosis of azurophil granule lumen proteins", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "extracellular region, azurophil granule lumen", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0X868-1", "A0A8V0XNR7-1", "A0A8V1AFG6-1", "A2JDL7-1", "F1NI04-1", "F1NML7-1", "F1NQI0-1", "A0A1D5PSE5-1", "P27043-1", "P30374-1", "A0A1D5PN36-1", "A0A1L1RSD2-1", "Q90629-1", "A0A8V0XXM5-1", "A0A8V0ZN26-1", "A0A8V1A4Q4-1", "A0A1D5PM49-1", "A0A8V0YHC8-1", "A0A8V0YL25-1", "A0A8V0YSD2-1", "E1BS94-1", "E1BSN7-1", "A0A8V0YVV2-1", "A0A8V0YW12-1", "A0A8V0Z0Z6-1", "A0A1D5PJC6-1", "A0A8V1AEN9-1", "F1NTQ2-1", "A0A1D5PXN4-1", "P00698-1", "A0A8V0Y6N9-1", "A0A8V0Y726-1", "A0A8V0ZQV0-1" ], "evidence": [ { "id": "R-GGA-6798751", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6798751" } ] }, { "id": "R-GGA-6800434", "name": "Exocytosis of ficolin-rich granule lumen proteins", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "extracellular region, ficolin-1-rich granule lumen", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A1D5PAA8-1", "A0A8V0X7U8-1", "A0A1D5PLH7-1", "A0A8V0XGV3-1", "A0A8V1AAF2-1", "A0A8V1ADZ5-1", "A0A8V1AIR0-1", "F1NI04-1", "A0A1D5PSE5-1", "A0A8V0XAS9-1", "O57535-1", "P08267-1", "Q90835-1", "A0A1L1RSD2-1", "R4GH41-1", "A0A8V0Y6Q3-1", "A0A8V1AMW1-1", "A0A8V0ZPK4-1", "A0A8V0ZQ64-1", "A0A8V0ZR27-1", "A0A8V0ZWJ4-1", "F1NN63-1", "A0A8V1A3K8-1", "A0A8V1A4Q4-1", "A0A8V0YHC8-1", "A0A8V0YXL9-1", "A0A8V0ZFP5-1", "A0A8V0ZG96-1", "A0A8V0ZTG8-1", "A0A8V0ZVL2-1", "A0A8V0Z0N7-1", "A0A8V0Z0Z6-1", "A0A8V0Z3A2-1", "F1NG97-1", "A0A8V0ZAK2-1", "A0A8V0ZG12-1", "A0A1D5PIQ5-1", "Q05744-1", "A0A8V0XX04-1", "A0A8V0XXA9-1", "A0A8V0YAA4-1", "A0A8V0Y4H1-1", "A0A8V0Y5M6-1", "A0A8V0YDR9-1", "A0A8V0YHT7-1" ], "evidence": [ { "id": "R-GGA-6800434", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6800434" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-1606845", "participant_name": "SO4(2-) [lysosomal lumen]", "crossref": [ { "id": "8144977", "database": "PubChem Substance", "url": "" }, { "id": "16189", "database": "ChEBI", "url": "" }, { "id": "C00059", "database": "COMPOUND", "url": "" } ] }, { "participant_id": "R-ALL-2104995", "participant_name": "GlcNAc(S)-Gal-GlcNAc(S)-Gal [lysosomal lumen]", "crossref": [ { "id": "63851", "database": "ChEBI", "url": "" }, { "id": "G80016QC", "database": "GlyTouCan", "url": "" }, { "id": "ZINC000096085298", "database": "ZINC", "url": "" }, { "id": "ZINC000096085297", "database": "ZINC", "url": "" }, { "id": "G06780", "database": "KEGG Glycan", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A0A1D5PAA8", "gene_name": "GYG1", "activity": [ { "ec_number": "2.4.1.186", "activity": "[1,4-alpha-D-glucosyl](n)-L-tyrosyl-[glycogenin] + UDP-alpha-D-glucose = [1,4-alpha-D-glucosyl](n+1)-L-tyrosyl-[glycogenin] + UDP + H(+).", "evidence": [ { "id": "A0A1D5PAA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PAA8" } ] }, { "ec_number": "2.4.1.186", "activity": "", "evidence": [ { "id": "A0A1D5PAA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PAA8" } ] } ] }, { "uniprot_ac": "A0A1D5PIQ5", "gene_name": "MAPK14", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PIQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PIQ5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A1D5PIQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PIQ5" } ] } ] }, { "uniprot_ac": "A0A1D5PJC6", "gene_name": "CPPED1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A1D5PJC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PJC6" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A1D5PJC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PJC6" } ] } ] }, { "uniprot_ac": "A0A1D5PLH7", "gene_name": "PRDX4", "activity": [ { "ec_number": "1.11.1.24", "activity": "a hydroperoxide + [thioredoxin]-dithiol = an alcohol + [thioredoxin]-disulfide + H2O.", "evidence": [ { "id": "A0A1D5PLH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLH7" } ] }, { "ec_number": "1.11.1.24", "activity": "", "evidence": [ { "id": "A0A1D5PLH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLH7" } ] } ] }, { "uniprot_ac": "A0A1D5PM49", "gene_name": "GALNS", "activity": [ { "ec_number": "3.1.6.4", "activity": "Hydrolysis of the 6-sulfate groups of the N-acetyl-D-galactosamine 6-sulfate units of chondroitin sulfate and of the D-galactose 6-sulfate units of keratan sulfate.", "evidence": [ { "id": "A0A1D5PM49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PM49" } ] }, { "ec_number": "3.1.6.4", "activity": "", "evidence": [ { "id": "A0A1D5PM49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PM49" } ] } ] }, { "uniprot_ac": "A0A1D5PN36", "gene_name": "LOC107054567", "activity": [ { "ec_number": "3.4.21.4", "activity": "Preferential cleavage: Arg-|-Xaa, Lys-|-Xaa.", "evidence": [ { "id": "A0A1D5PN36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PN36" } ] }, { "ec_number": "3.4.21.4", "activity": "", "evidence": [ { "id": "A0A1D5PN36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PN36" } ] } ] }, { "uniprot_ac": "A0A1D5PSE5", "gene_name": "ACLY", "activity": [ { "ec_number": "2.3.3.8", "activity": "oxaloacetate + acetyl-CoA + ADP + phosphate = citrate + ATP + CoA.", "evidence": [ { "id": "A0A1D5PSE5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PSE5" } ] }, { "ec_number": "2.3.3.8", "activity": "", "evidence": [ { "id": "A0A1D5PSE5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PSE5" } ] } ] }, { "uniprot_ac": "A0A1D5PXN4", "gene_name": "PRKCD", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PXN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PXN4" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A1D5PXN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PXN4" } ] } ] }, { "uniprot_ac": "A0A1L1RSD2", "gene_name": "GUSB", "activity": [ { "ec_number": "3.2.1.31", "activity": "a beta-D-glucuronoside + H2O = D-glucuronate + an alcohol.", "evidence": [ { "id": "A0A1L1RSD2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RSD2" } ] }, { "ec_number": "3.2.1.31", "activity": "", "evidence": [ { "id": "A0A1L1RSD2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RSD2" } ] } ] }, { "uniprot_ac": "A0A8V0X7U8", "gene_name": "ALDOA", "activity": [ { "ec_number": "4.1.2.13", "activity": "beta-D-fructose 1,6-bisphosphate = D-glyceraldehyde 3-phosphate + dihydroxyacetone phosphate.", "evidence": [ { "id": "A0A8V0X7U8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X7U8" } ] }, { "ec_number": "4.1.2.13", "activity": "", "evidence": [ { "id": "A0A8V0X7U8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X7U8" } ] } ] }, { "uniprot_ac": "A0A8V0X868", "gene_name": "GGH", "activity": [ { "ec_number": "3.4.19.9", "activity": "(6S)-5,6,7,8-tetrahydrofolyl-(gamma-L-Glu)(n) + (n-1) H2O = (6S)-5,6,7,8-tetrahydrofolate + (n-1) L-glutamate.", "evidence": [ { "id": "A0A8V0X868", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X868" } ] }, { "ec_number": "3.4.19.9", "activity": "", "evidence": [ { "id": "A0A8V0X868", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X868" } ] } ] }, { "uniprot_ac": "A0A8V0XAS9", "gene_name": "CAPN1", "activity": [ { "ec_number": "3.4.22.52", "activity": "Broad endopeptidase specificity.", "evidence": [ { "id": "A0A8V0XAS9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XAS9" } ] }, { "ec_number": "3.4.22.52", "activity": "", "evidence": [ { "id": "A0A8V0XAS9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XAS9" } ] } ] }, { "uniprot_ac": "A0A8V0XGV3", "gene_name": "DDX3X", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XGV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XGV3" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0XGV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XGV3" } ] } ] }, { "uniprot_ac": "A0A8V0XNR7", "gene_name": "CTSC", "activity": [ { "ec_number": "3.4.14.1", "activity": "Release of an N-terminal dipeptide, Xaa-Yaa-|-Zaa-, except when Xaa is Arg or Lys, or Yaa or Zaa is Pro.", "evidence": [ { "id": "A0A8V0XNR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNR7" } ] }, { "ec_number": "3.4.14.1", "activity": "", "evidence": [ { "id": "A0A8V0XNR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNR7" } ] } ] }, { "uniprot_ac": "A0A8V0XX04", "gene_name": "QPCT", "activity": [ { "ec_number": "2.3.2.5", "activity": "N-terminal L-glutaminyl-[peptide] = N-terminal 5-oxo-L-prolyl-[peptide] + NH4(+).", "evidence": [ { "id": "A0A8V0XX04", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XX04" } ] }, { "ec_number": "2.3.2.5", "activity": "", "evidence": [ { "id": "A0A8V0XX04", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XX04" } ] } ] }, { "uniprot_ac": "A0A8V0XXA9", "gene_name": "GPI", "activity": [ { "ec_number": "5.3.1.9", "activity": "alpha-D-fructose 6-phosphate = beta-D-fructose 6-phosphate.", "evidence": [ { "id": "A0A8V0XXA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XXA9" } ] }, { "ec_number": "5.3.1.9", "activity": "", "evidence": [ { "id": "A0A8V0XXA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XXA9" } ] } ] }, { "uniprot_ac": "A0A8V0XXM5", "gene_name": "ARSA", "activity": [ { "ec_number": "3.1.6.8", "activity": "an N-acyl-1-beta-D-(3-O-sulfo)-galactosyl-sphing-4-enine + H2O = a beta-D-galactosyl-(1<->1')-N-acylsphing-4-enine + sulfate + H(+).", "evidence": [ { "id": "A0A8V0XXM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XXM5" } ] }, { "ec_number": "3.1.6.8", "activity": "", "evidence": [ { "id": "A0A8V0XXM5", "database": 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"id": "A0A8V0Y726", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y726" } ] }, { "ec_number": "5.3.4.1", "activity": "", "evidence": [ { "id": "A0A8V0Y726", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y726" } ] } ] }, { "uniprot_ac": "A0A8V0YAA4", "gene_name": "XRCC6", "activity": [ { "ec_number": "4.2.99.18", "activity": "2'-deoxyribonucleotide-(2'-deoxyribose 5'-phosphate)-2'-deoxyribonucleotide-DNA = a 3'-end 2'-deoxyribonucleotide-(2,3-dehydro-2,3-deoxyribose 5'-phosphate)-DNA + a 5'-end 5'-phospho-2'-deoxyribonucleoside-DNA + H(+).", "evidence": [ { "id": "A0A8V0YAA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAA4" } ] }, { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YAA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAA4" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "A0A8V0YAA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAA4" } ] }, { "ec_number": "4.2.99.18", "activity": "", "evidence": [ { "id": "A0A8V0YAA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAA4" } ] } ] }, { "uniprot_ac": "A0A8V0YDR9", "gene_name": "KCMF1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YDR9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDR9" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0YDR9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDR9" } ] } ] }, { "uniprot_ac": "A0A8V0YHC8", "gene_name": "VCP", "activity": [ { "ec_number": "3.6.4.6", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YHC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHC8" } ] }, { "ec_number": "3.6.4.6", "activity": "", "evidence": [ { "id": "A0A8V0YHC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHC8" } ] } ] }, { "uniprot_ac": "A0A8V0YHT7", "gene_name": "DERA", "activity": [ { "ec_number": "4.1.2.4", "activity": "2-deoxy-D-ribose 5-phosphate = D-glyceraldehyde 3-phosphate + acetaldehyde.", "evidence": [ { "id": "A0A8V0YHT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHT7" } ] }, { "ec_number": "4.1.2.4", "activity": "", "evidence": [ { "id": "A0A8V0YHT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHT7" } ] } ] }, { "uniprot_ac": "A0A8V0YL25", "gene_name": "PRDX6", "activity": [ { "ec_number": "1.11.1.27", "activity": "a hydroperoxide + 2 glutathione = an alcohol + glutathione disulfide + H2O.", "evidence": [ { "id": "A0A8V0YL25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL25" } ] }, { "ec_number": "1.11.1.27", "activity": "", "evidence": [ { "id": "A0A8V0YL25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL25" } ] } ] }, { "uniprot_ac": "A0A8V0YSD2", "gene_name": "FUCA1", "activity": [ { "ec_number": "3.2.1.51", "activity": "an alpha-L-fucoside + H2O = L-fucose + an alcohol.", "evidence": [ { "id": "A0A8V0YSD2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSD2" } ] }, { "ec_number": "3.2.1.51", "activity": "", "evidence": [ { "id": "A0A8V0YSD2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSD2" } ] } ] }, { "uniprot_ac": "A0A8V0YVV2", "gene_name": "GLA", "activity": [ { "ec_number": "3.2.1.-", "activity": "", "evidence": [ { "id": "A0A8V0YVV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YVV2" } ] } ] }, { "uniprot_ac": "A0A8V0YW12", "gene_name": "FRK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YW12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YW12" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0YW12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YW12" } ] } ] }, { "uniprot_ac": "A0A8V0YXL9", "gene_name": "MMP9", "activity": [ { "ec_number": "3.4.24.35", "activity": "Cleavage of gelatin types I and V and collagen types IV and V.", "evidence": [ { "id": "A0A8V0YXL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXL9" } ] }, { "ec_number": "3.4.24.35", "activity": "", "evidence": [ { "id": "A0A8V0YXL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXL9" } ] } ] }, { "uniprot_ac": "A0A8V0Z0N7", "gene_name": "PPIA", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "A0A8V0Z0N7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z0N7" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "A0A8V0Z0N7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z0N7" } ] } ] }, { "uniprot_ac": "A0A8V0Z0Z6", "gene_name": "GLB1", "activity": [ { "ec_number": "3.2.1.23", "activity": "Hydrolysis of terminal non-reducing beta-D-galactose residues in beta-D-galactosides.", "evidence": [ { "id": "A0A8V0Z0Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z0Z6" } ] }, { "ec_number": "3.2.1.23", "activity": "", "evidence": [ { "id": "A0A8V0Z0Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z0Z6" } ] } ] }, { "uniprot_ac": "A0A8V0Z3A2", "gene_name": "PPIE", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", 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"database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG12" } ] } ] }, { "uniprot_ac": "A0A8V0ZG96", "gene_name": "PKLR", "activity": [ { "ec_number": "2.7.1.40", "activity": "ITP + pyruvate = IDP + phosphoenolpyruvate + H(+).", "evidence": [ { "id": "A0A8V0ZG96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG96" } ] }, { "ec_number": "2.7.1.40", "activity": "", "evidence": [ { "id": "A0A8V0ZG96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG96" } ] } ] }, { "uniprot_ac": "A0A8V0ZN26", "gene_name": "LOC121106429", "activity": [ { "ec_number": "3.4.21.4", "activity": "Preferential cleavage: Arg-|-Xaa, Lys-|-Xaa.", "evidence": [ { "id": "A0A8V0ZN26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN26" } ] }, { "ec_number": "3.4.21.4", "activity": "", "evidence": [ { "id": "A0A8V0ZN26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN26" } ] } ] }, { 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"database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ64" } ] }, { "ec_number": "2.4.1.25", "activity": "", "evidence": [ { "id": "A0A8V0ZQ64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ64" } ] }, { "ec_number": "3.2.1.33", "activity": "", "evidence": [ { "id": "A0A8V0ZQ64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ64" } ] } ] }, { "uniprot_ac": "A0A8V0ZQV0", "gene_name": "VAT1", "activity": [ { "ec_number": "1.6.5.5", "activity": "2 1,2-naphthoquinone + NADPH + H(+) = 2 1,2-naphthosemiquinone + NADP(+).", "evidence": [ { "id": "A0A8V0ZQV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQV0" } ] }, { "ec_number": "1.6.5.5", "activity": "", "evidence": [ { "id": "A0A8V0ZQV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQV0" } ] } ] }, { "uniprot_ac": "A0A8V0ZR27", "gene_name": "PAFAH1B2", "activity": [ { "ec_number": "3.1.1.47", "activity": "a 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine + H2O = a 1-O-alkyl-sn-glycero-3-phosphocholine + acetate + H(+).", "evidence": [ { "id": "A0A8V0ZR27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR27" } ] }, { "ec_number": "3.1.1.47", "activity": "", "evidence": [ { "id": "A0A8V0ZR27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR27" } ] } ] }, { "uniprot_ac": "A0A8V0ZTG8", "gene_name": "PFKL", "activity": [ { "ec_number": "2.7.1.11", "activity": "beta-D-fructose 6-phosphate + ATP = beta-D-fructose 1,6-bisphosphate + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZTG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTG8" } ] }, { "ec_number": "2.7.1.11", "activity": "", "evidence": [ { "id": "A0A8V0ZTG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTG8" } ] } ] }, { "uniprot_ac": "A0A8V0ZVL2", "gene_name": "CAT", "activity": [ { "ec_number": "1.11.1.6", "activity": "2 H2O2 = O2 + 2 H2O.", "evidence": [ { "id": "A0A8V0ZVL2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVL2" } ] }, { "ec_number": "1.11.1.6", "activity": "", "evidence": [ { "id": "A0A8V0ZVL2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVL2" } ] } ] }, { "uniprot_ac": "A0A8V0ZWJ4", "gene_name": "ALOX5", "activity": [ { "ec_number": "1.13.11.34", "activity": "(5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 = leukotriene A4 + H2O.", "evidence": [ { "id": "A0A8V0ZWJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWJ4" } ] }, { "ec_number": "1.13.11.34", "activity": "", "evidence": [ { "id": "A0A8V0ZWJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWJ4" } ] } ] }, { "uniprot_ac": "A0A8V1A3K8", "gene_name": "APEH", "activity": [ { "ec_number": "3.4.19.1", "activity": "Internal cleavage of oxidized and glycated proteins.", "evidence": [ { "id": "A0A8V1A3K8", "database": "UniProtKB", "url": 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"gene_name": "DPP7", "activity": [ { "ec_number": "3.4.14.2", "activity": "Release of an N-terminal dipeptide, Xaa-Yaa-|-, preferentially when Yaa is Ala or Pro. 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Does not cleave the 4-Gln-|-His-5 bond in B chain of insulin.", "evidence": [ { "id": "Q05744", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q05744" } ] }, { "ec_number": "3.4.23.5", "activity": "", "evidence": [ { "id": "Q05744", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q05744" } ] } ] }, { "uniprot_ac": "Q90629", "gene_name": "", "activity": [ { "ec_number": "3.4.21.4", "activity": "Preferential cleavage: Arg-|-Xaa, Lys-|-Xaa.", "evidence": [ { "id": "Q90629", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q90629" } ] }, { "ec_number": "3.4.21.4", "activity": "", "evidence": [ { "id": "Q90629", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q90629" } ] } ] }, { "uniprot_ac": "Q90835", "gene_name": "EEF1A", "activity": [ { "ec_number": "3.6.5.-", "activity": "", "evidence": [ { "id": "Q90835", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q90835" } ] } ] }, { "uniprot_ac": 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}, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1NI14-1", "uniprot_ac": "F1NI14", "uniprot_id": "F1NI14_CHICK", "mass": { "chemical_mass": 61042.0, "monoisotopic_mass": 61042.0 }, "refseq": { "ac": "XP_015128909", "name": "gamma-taxilin isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015128909" }, "gene_names": [ { "name": "TXLNG", "type": "recommended", "evidence": [ { "id": "F1NI14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NI14" } ] }, { "name": "TXLNG", "type": "synonym", "evidence": [ { "id": "XP_015128909", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015128909" } ] } ], "protein_names": [ { "name": "Taxilin gamma", "type": "synonym", "evidence": [ { "id": "F1NI14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NI14/entry#names_and_taxonomy" } ] }, { "name": "gamma-taxilin isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015128909", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015128909" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015128909", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015128909" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NI14", "url": "https://www.uniprot.org/uniprotkb/F1NI14" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TXLNG", "url": "https://www.uniprot.org/uniprotkb/F1NI14", "locus": { "chromosome": "1", "start_pos": 121476245, "end_pos": 121497940, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010002402", "url": "https://www.ensembl.org/id/ENSGALG00010002402" } ] } } ], "crossref": [ { "id": "F1NI14", "url": "https://alphafold.ebi.ac.uk/entry/F1NI14", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000016547", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000016547", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "418618", "url": "https://www.ncbi.nlm.nih.gov/gene/418618", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR026183", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026183", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:418618", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418618", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PKELNTA", "url": "https://omabrowser.org/oma/group/PKELNTA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1NI14", "url": "https://www.orthodb.org/?gene=F1NI14", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16127", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16127", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16127:SF14", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16127:SF14", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF09728", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09728", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015128909", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015128909", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1NI14", "url": "https://www.uniprot.org/uniprotkb/F1NI14", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NI14-1", "url": "https://www.uniprot.org/uniprotkb/F1NI14-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MATRGAEAARGGGSGGGGAAGRSRRHSQGRGGEEAVAGASGSPELVVGAMEEAGSQEMGMNNQDQLMNSRCNELSNTALQHTQPNCDGLEHTDMLEGTEYITKNRKLLGSTCCSQESREETPGREEARTDPPDGQQDPESEKHKEKTLGKEVLLLMQALNTLSTPEEKLAALCKKYADLLEESRNVQKQMKILQKKQAQVVKEKVHLQSEHSKAILARSKLESLCRELQRHNKTLKEENIQQAREEEERRKEATAHFQITLNEIQAQLEQHDIHNAKLRQENIELGEKLKKLIEQYALREEHIDKVFKHKELQQQLVDAKLQQTTQLIKEAEEKHQREREFLLKEATESRHKCEQMKQQEAQLKQQLSLYMDKFEEFQTTMAKSNELFTTFRQEMEKMTKKIKKLEKETIVWRTKWENNNKALLQMAEEKTVRDKEYKGFQIKLERLEKLCRALQTERNELNEKVEVLKEQVSLREADVDLAVQVLQSCTLNSHEELESPTDTEGGIQPSVESHAANRSEKTVSTSPVPGTESVD", "length": 535, "header": "tr|F1NI14-1|F1NI14_CHICK Isoform 1 of Taxilin gamma OS=Gallus gallus OX=9031 GN=TXLNG PE=3 SV=4 CANONICAL=F1NI14-1" }, "isoforms": [ { "isoform_ac": "F1NI14-1", "url": "https://www.uniprot.org/uniprotkb/F1NI14/entry#F1NI14-1", "sequence": { "sequence": "MATRGAEAARGGGSGGGGAAGRSRRHSQGRGGEEAVAGASGSPELVVGAMEEAGSQEMGMNNQDQLMNSRCNELSNTALQHTQPNCDGLEHTDMLEGTEYITKNRKLLGSTCCSQESREETPGREEARTDPPDGQQDPESEKHKEKTLGKEVLLLMQALNTLSTPEEKLAALCKKYADLLEESRNVQKQMKILQKKQAQVVKEKVHLQSEHSKAILARSKLESLCRELQRHNKTLKEENIQQAREEEERRKEATAHFQITLNEIQAQLEQHDIHNAKLRQENIELGEKLKKLIEQYALREEHIDKVFKHKELQQQLVDAKLQQTTQLIKEAEEKHQREREFLLKEATESRHKCEQMKQQEAQLKQQLSLYMDKFEEFQTTMAKSNELFTTFRQEMEKMTKKIKKLEKETIVWRTKWENNNKALLQMAEEKTVRDKEYKGFQIKLERLEKLCRALQTERNELNEKVEVLKEQVSLREADVDLAVQVLQSCTLNSHEELESPTDTEGGIQPSVESHAANRSEKTVSTSPVPGTESVD", "length": 535, "header": "tr|F1NI14-1|F1NI14_CHICK Isoform 1 of Taxilin gamma OS=Gallus gallus OX=9031 GN=TXLNG PE=3 SV=4 CANONICAL=F1NI14-1" }, "locus": { "chromosome": "1", "start_pos": 121497918, "end_pos": 121479222, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010005511.1", "url": "https://www.ensembl.org/id/ENSGALT00010005511.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010003350.1", "url": "https://www.ensembl.org/id/ENSGALP00010003350.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:418618", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418618", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A061HYT0-1", "protein_name": "Gamma-taxilin isoform X1", "gene_name": "Txlng", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MATRIEEAARGRGGGTEEATEGEGGERRGSPRQKFEIETMEEAGICGLEVKEDMFCNSQANDILQHQDSSCGGTTKTHSLEGDEGSDFITKNMNLVSSAFRAQESREEIPGREARTGPPDGQQDSECSRNKEKTLGKEVLLLMQALNTLSTPEEKLAALCKKYADLLEESRNVQKQMKILQKKQAQIVKEKVHLQSEHSKAILARSKLESLCRELQRHNKTLKEENLQQAREEEERRKEATAHFQITLNEIQAQLEQHDIHNAKLRQENIELGEKLKKLIEQYALREEHIDKVFKHKELQQQLVDAKLQQTTQLIKEADEKHQREREFLLKEATESRHKYEQMKQQEVQLKQQLSLYMDKFEEFQTTMAKSNELFTTFRQEMEKMTKKIKKLEKETMIWRTKWENNNKALLQMAEEKTVRDKEYKAFQIKLERLEKLCRALQTERNELNEKVEVLKEQVSIKAADGDLVSPAMQPCAALDSLKEMNTSRRALGMHLEARAKAKSVSERRSATQKPSSSGSAKGIESVD", "length": 528 }, "evidence": [ { "id": "F1NI14", "url": "https://omabrowser.org/oma/group/F1NI14/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A0G2QC39-1", "protein_name": "Taxilin gamma", "gene_name": "Txlng", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MATRLEEATRGRGGGTEEAIEGGPGGRGGRRRSPPEKFEIGTMEEARICELGVKADMVCKSQANDILQHQDSSCGGTTKKHSLEGDEGSDFVTNTRNLVSSVFCTQETREEIPGREARTGPPDGQQDSECSRNKEKTLGKEVLLLMQALNTLSTPEEKLAALCKKYADLLEESRNVQKQMKILQKKQAQIVKEKVHLQSEHSKAILARSKLESLCRELQRHNKTLKEENMQQAREEEERRKEATAHFQITLNEIQAQLEQHDIHNAKLRQENIELGEKLKKLIEQYALREEHIDKVFKHKELQQQLVDAKLQQTTQLIKEADEKHQREREFLLKEATESRHKYEQMKQQEVQLKQQLSLYMDKFEEFQTTMAKSNELFTTFRQEMEKMTKKIKKLEKETIIWRTKWENNNKALLQMAEEKTVRDKEYKAFQIKLERLEKLCRALQTERNELNEKVEVLKEQVSIKAADGDLVSPTTQPCAVLDSFKEMNTSRALGMPLEARAKTKSVSERSAAQKPSSSGSAAQGIESVD", "length": 530 }, "evidence": [ { "id": "F1NI14", "url": "https://omabrowser.org/oma/group/F1NI14/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A287BFL6-1", "protein_name": "Taxilin gamma", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MATRVEEAARGRGGGVEEAIEAGRGGRRRSPRQKFVMGTMEEAGMCGLAVKADMLHNSQPNDILQHQDSHCGGTSNRHALEEDASSDFITKSRSLVSPAYCTQESREEIPGREARTDPPDGQQDSECSRSKEKTLGKEVLLLMQALNTLSTPEEKLAALCKKYADLLEESRNVQKQMKILQKKQAQIVKEKVHLQSEHSKAILARSKLESLCRELQRHNKTLKEENMQQAREEEERRKEATAHFQMTLNEIQAQLEQHDLHNAKLRQENMELGEKLKKLIEQYALREEHIDKVFKHKELQQQLVDAKLQQTTQLIKEADEKHQREREFLLKEATESRHKYEQMKQQEVQLKQQLSLYMDKFEEFQTTMAKSNELFTTFRQEMEKMTKKIKKLEKETIIWRSKWENNNKALLQMAEEKTVRDKEYKAFQIKLDRLEKLCRALQTERNELNEKVEVLKGQVAGRAAGAGPAPPGAQPCAALPAPQESRTAWPVAPGVPPEAASPGAGPGIESVD", "length": 512 }, "evidence": [ { "id": "F1NI14", "url": "https://omabrowser.org/oma/group/F1NI14/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0AAA9TAG9-1", "protein_name": "Taxilin gamma", "gene_name": "TXLNG", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MATRVEEAARGRGGGAEEAVEAGRGGRRRSPRQKFVIGTMEEAGMCGLGVKADMLHNSQSNDILQHQDSHCGSTSNKHSLEEDARSDFITKGRSLVSPAYCTRESREEIPGREARTDPPDGQQDSECSRSKDKALGKEVLLLMQALNTLSTPEEKLAALCKKYADLLEESRNVQKQMKILQKKQAQIMKEKVHLQSEHSKAILARSKLESLCRELQRHNKTLKEENMQQAREEEERRKEATAHFQITLNEIQAQLEQHDMHNAKLRQENIELGEKLKKLIEQYALREEHIDKVFKHKELQQQLVDAKLQQTTQLIKEADEKHQREREFLLKEATESRHKYEQMKQQEIQLKQQLSLYMDKFEEFQTTMAKSNELFTTFRQEMEKMTKKIKKLEKETIVWRTKWENNNKALLQMAEEKTVRDKEYKAFQIKLERLEKLCRALQTERNELNEKVEVLKEQVSGRAAGGGPAPPEAQPCATSAPPEESGATWQSAARVIPEAGSLGAGPGIESVD", "length": 512 }, "evidence": [ { "id": "F1NI14", "url": "https://omabrowser.org/oma/group/F1NI14/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q8BHN1-1", "protein_name": "Gamma-taxilin", "gene_name": "Txlng", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MATRLEEVTRGRGGGTEEASEGGRGGRRRSPPQKFEIGTMEEARICGLGVKADMVCNSQANDILQHQDPSCGGTTKKHSLEGDEGSDFITKNRNLVSSVFCTQEKREEIPGREARTGPPDGQQDSECSRNKEKTLGKEVLLLMQALNTLSTPEEKLAALCKKYADLLEESRNVQKQMKILQKKQAQIVKEKVHLQSEHSKAILARSKLESLCRELQRHNKTLKEENMQQAREEEERRKEATAHFQITLNEIQAQLEQHDIHNAKLRQENIELGEKLKKLIEQYALREEHIDKVFKHKELQQQLVDAKLQQTTQLIKEADEKHQREREFLLKEATESRHKYEQMKQQEVQLKQQLSLYMDKFEEFQTTMAKSNELFTTFRQEMEKMTKKIKKLEKETIIWRTKWENNNKALLQMAEEKTVRDKEYKAFQIKLERLEKLCRALQTERNELNEKVEVLKEQVSIKAADGDLVSPATQPCAVLDSFKETSRRTLGMHLEARAKSVCEKSAAQKPSSSGSPAQGIESVD", "length": 524 }, "evidence": [ { "id": "F1NI14", "url": "https://omabrowser.org/oma/group/F1NI14/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9NUQ3-1", "protein_name": "Gamma-taxilin", "gene_name": "TXLNG", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MATRVEEAARGRGGGAEEATEAGRGGRRRSPRQKFEIGTMEEAGICGLGVKADMLCNSQSNDILQHQGSNCGGTSNKHSLEEDEGSDFITENRNLVSPAYCTQESREEIPGGEARTDPPDGQQDSECNRNKEKTLGKEVLLLMQALNTLSTPEEKLAALCKKYADLLEESRSVQKQMKILQKKQAQIVKEKVHLQSEHSKAILARSKLESLCRELQRHNKTLKEENMQQAREEEERRKEATAHFQITLNEIQAQLEQHDIHNAKLRQENIELGEKLKKLIEQYALREEHIDKVFKHKELQQQLVDAKLQQTTQLIKEADEKHQREREFLLKEATESRHKYEQMKQQEVQLKQQLSLYMDKFEEFQTTMAKSNELFTTFRQEMEKMTKKIKKLEKETIIWRTKWENNNKALLQMAEEKTVRDKEYKALQIKLERLEKLCRALQTERNELNEKVEVLKEQVSIKAAIKAANRDLATPVMQPCTALDSHKELNTSSKRALGAHLEAEPKSQRSAVQKPPSTGSAPAIESVD", "length": 528 }, "evidence": [ { "id": "F1NI14", "url": "https://omabrowser.org/oma/group/F1NI14/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F1NI14", "url": "https://www.uniprot.org/uniprotkb/F1NI14" } ], "pmid": "" }, { "name": "nuclear membrane", "id": "GO:0031965", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031965", "evidence": [ { "database": "UniProtKB", "id": "F1NI14", "url": "https://www.uniprot.org/uniprotkb/F1NI14" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "syntaxin binding", "id": "GO:0019905", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019905", "evidence": [ { "database": "UniProtKB", "id": "F1NI14", "url": "https://www.uniprot.org/uniprotkb/F1NI14" } ], "pmid": "" }, { "name": "DNA-binding transcription factor binding", "id": "GO:0140297", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140297", "evidence": [ { "database": "UniProtKB", "id": "F1NI14", "url": "https://www.uniprot.org/uniprotkb/F1NI14" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "regulation of bone mineralization", "id": "GO:0030500", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030500", "evidence": [ { "database": "UniProtKB", "id": "F1NI14", "url": "https://www.uniprot.org/uniprotkb/F1NI14" } ], "pmid": "" }, { "name": "regulation of cell cycle process", "id": "GO:0010564", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010564", "evidence": [ { "database": "UniProtKB", "id": "F1NI14", "url": "https://www.uniprot.org/uniprotkb/F1NI14" } ], "pmid": "" }, { "name": "regulation of cell cycle", "id": "GO:0051726", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051726", "evidence": [ { "database": "UniProtKB", "id": "F1NI14", "url": "https://www.uniprot.org/uniprotkb/F1NI14" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 232, "end_pos": 234, "annotation": "n_glycosylation_sequon" }, { "start_pos": 517, "end_pos": 519, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1NI14-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 535, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1NI14-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1NI14" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 232, "end_pos": 234 }, { "start_pos": 517, "end_pos": 519 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1NI76-1", "uniprot_ac": "F1NI76", "uniprot_id": "F1NI76_CHICK", "mass": { "chemical_mass": 51317.0, "monoisotopic_mass": 51317.0 }, "refseq": { "ac": "XP_416263", "name": "inward rectifier potassium channel 4 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_416263" }, "gene_names": [ { "name": "KCNJ4", "type": "recommended", "evidence": [ { "id": "F1NI76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NI76" } ] }, { "name": "KCNJ4", "type": "synonym", "evidence": [ { "id": "XP_416263", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_416263" } ] } ], "protein_names": [ { "name": "Potassium inwardly rectifying channel subfamily J member 4", "type": "synonym", "evidence": [ { "id": "F1NI76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NI76/entry#names_and_taxonomy" } ] }, { "name": "inward rectifier potassium channel 4 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_416263", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_416263" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process On Jun 19, 2013 this sequence version replaced XP_416263.3. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_416263", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_416263" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NI76", "url": "https://www.uniprot.org/uniprotkb/F1NI76" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "KCNJ4", "url": "https://www.uniprot.org/uniprotkb/F1NI76", "locus": { "chromosome": "1", "start_pos": 50956602, "end_pos": 50945310, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012887", "url": "https://www.ensembl.org/id/ENSGALG00010012887" } ] } } ], "crossref": [ { "id": "F1NI76", "url": "https://alphafold.ebi.ac.uk/entry/F1NI76", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000012254", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000012254", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "395903", "url": "https://www.ncbi.nlm.nih.gov/gene/395903", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003273", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003273", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013518", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013518", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013673", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013673", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014756", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014756", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016449", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016449", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040445", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040445", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041647", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041647", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:395903", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:395903", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "F1NI76", "url": "https://www.orthodb.org/?gene=F1NI76", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11767", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11767", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11767:SF53", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11767:SF53", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01007", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01007", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08466", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08466", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17655", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17655", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-1296041", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1296041", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-1296053", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1296053", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-5576886", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5576886", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-997272", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-997272", "database": "Reactome", "categories": [ "Enzyme and Pathway" 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"publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1NIC5-1", "uniprot_ac": "F1NIC5", "uniprot_id": "F1NIC5_CHICK", "mass": { "chemical_mass": 10686.0, "monoisotopic_mass": 10686.0 }, "refseq": { "ac": "NP_001289039", "name": "mitochondrial import inner membrane translocase subunit Tim8 A", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001289039" }, "gene_names": [ { "name": "TIMM8A", "type": "recommended", "evidence": [ { "id": "F1NIC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NIC5" } ] }, { "name": "TIMM8A", "type": "synonym", "evidence": [ { "id": "NP_001289039", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001289039" } ] } ], "protein_names": [ { "name": "Mitochondrial import inner membrane translocase subunit", "type": "recommended", "evidence": [ { "id": "F1NIC5", "database": "UniProtKB", "url": 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The reference sequence was derived from JAENSK010000071.1. On Oct 1, 2014 this sequence version replaced XP_420185.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001289039", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001289039" } ] }, { "annotation": "Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.", "evidence": [ { "database": "UniProtKB", "id": "F1NIC5", "url": "https://www.uniprot.org/uniprotkb/F1NIC5#function" }, { "database": "UniProtKB", "id": "RU367043", "url": "https://www.uniprot.org/uniprotkb/RU367043#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NIC5", "url": "https://www.uniprot.org/uniprotkb/F1NIC5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TIMM8A", "url": "https://www.uniprot.org/uniprotkb/F1NIC5", "locus": { "chromosome": "4", "start_pos": 1998292, "end_pos": 1995925, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010015985", "url": 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gallus OX=9031 GN=TIMM8A PE=1 SV=3 CANONICAL=F1NIC5-1" }, "isoforms": [ { "isoform_ac": "F1NIC5-1", "url": "https://www.uniprot.org/uniprotkb/F1NIC5/entry#F1NIC5-1", "sequence": { "sequence": "MEAPSGGGLGGADPQLQRFIEVETQKQRFQQLVHQMTELCWEKCMDKPGPKLDSRAETCFVNCVERFIDTSQFILNRLEQTQKSKSAFSESLSD", "length": 94, "header": "tr|F1NIC5-1|F1NIC5_CHICK Isoform 1 of Mitochondrial import inner membrane translocase subunit OS=Gallus gallus OX=9031 GN=TIMM8A PE=1 SV=3 CANONICAL=F1NIC5-1" }, "locus": { "chromosome": "4", "start_pos": 1996555, "end_pos": 1996005, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010038519.1", "url": "https://www.ensembl.org/id/ENSGALT00010038519.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010022289.1", "url": "https://www.ensembl.org/id/ENSGALP00010022289.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:422190", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422190", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "Q9WVA2-1", "protein_name": "Mitochondrial import inner membrane translocase subunit Tim8 A", "gene_name": "Timm8a1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MESSTSSSGSALGAVDPQLQHFIEVETQKQRFQQLVHQMTELCWEKCMDKPGPKLDSRAEACFVNCVERFIDTSQFILNRLEQTQKSKPVFSESLSD", "length": 97 }, "evidence": [ { "id": "F1NIC5", "url": "https://omabrowser.org/oma/group/F1NIC5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "mitochondrial intermembrane space chaperone complex", "id": "GO:0042719", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042719", "evidence": [ { "database": "UniProtKB", "id": "F1NIC5", "url": "https://www.uniprot.org/uniprotkb/F1NIC5" } ], "pmid": "" }, { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "F1NIC5", "url": "https://www.uniprot.org/uniprotkb/F1NIC5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "F1NIC5", "url": "https://www.uniprot.org/uniprotkb/F1NIC5" } ], "pmid": "" }, { "name": "protein insertion into mitochondrial inner membrane", "id": "GO:0045039", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045039", "evidence": [ { "database": "UniProtKB", "id": "F1NIC5", "url": "https://www.uniprot.org/uniprotkb/F1NIC5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "F1NIC5", "url": "https://www.uniprot.org/uniprotkb/F1NIC5" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "F1NIC5", "url": "https://www.uniprot.org/uniprotkb/F1NIC5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1NIC5-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 94, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1NIC5-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1NIC5" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1NIC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NIC5" }, { "id": "PF02953", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02953" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Tim10-like", "eco_id": "ECO_0000259", "start_pos": 19, "end_pos": 80, "start_aa": "Phe", "end_aa": "Gln", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1NID3-1", "uniprot_ac": "F1NID3", "uniprot_id": "F1NID3_CHICK", "mass": { "chemical_mass": 102286.0, "monoisotopic_mass": 102286.0 }, "refseq": { "ac": "XP_015146381", "name": "ZZ-type zinc finger-containing protein 3 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015146381" }, "gene_names": [ { "name": "ZZZ3", "type": "recommended", "evidence": [ { "id": "F1NID3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NID3" } ] }, { "name": "ZZZ3", "type": "synonym", "evidence": [ { "id": "XP_015146381", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015146381" } ] } ], "protein_names": [ { "name": "ZZ-type zinc finger-containing protein 3", "type": "recommended", "evidence": [ { "id": "F1NID3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NID3/entry#names_and_taxonomy" } ] }, { "name": "ZZ-type zinc finger-containing protein 3 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015146381", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015146381" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052539.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015146381", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015146381" } ] }, { "annotation": "Histone H3 reader that is required for the ATAC complex-mediated maintenance of histone acetylation and gene activation. Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4.", "evidence": [ { "database": "UniProtKB", "id": "F1NID3", "url": "https://www.uniprot.org/uniprotkb/F1NID3#function" }, { "database": "UniProtKB", "id": "ARBA00053098", "url": "https://www.uniprot.org/uniprotkb/ARBA00053098#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NID3", "url": "https://www.uniprot.org/uniprotkb/F1NID3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ZZZ3", "url": "https://www.uniprot.org/uniprotkb/F1NID3", "locus": { "chromosome": "8", "start_pos": 18767000, "end_pos": 18736185, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010022359", "url": "https://www.ensembl.org/id/ENSGALG00010022359" } ] } } ], "crossref": [ { "id": "F1NID3", "url": "https://alphafold.ebi.ac.uk/entry/F1NID3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000008988", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000008988", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00167", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00167", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd02341", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02341", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "424554", "url": "https://www.ncbi.nlm.nih.gov/gene/424554", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000433", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000433", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001005", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001005", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009057", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009057", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017930", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017930", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037830", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037830", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041981", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041981", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043145", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043145", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:424554", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424554", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PCTDSQV", "url": "https://omabrowser.org/oma/group/PCTDSQV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1NID3", "url": "https://www.orthodb.org/?gene=F1NID3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22705", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22705", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22705:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22705:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00249", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00249", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00569", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00569", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015146381", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015146381", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1NID3", "url": "https://www.uniprot.org/uniprotkb/F1NID3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NID3-1", "url": "https://www.uniprot.org/uniprotkb/F1NID3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAASRSTRVTRSTVGLNGLDENFCGRTLRNRSIAHPEEVSPHPQVRSRSPKKRPDSVQTQKGSNGGRTTDLKQQSTRESWVSPRKRGLSTSEKDNVDKQTVENCEKRQGEPVSPVLKRIKRCLRSEAPNSSEEDLSTKTEKESLERKSLVSDNDAVSPGTKRACRCLILDDCDKREVKKVNICAEGFNNSAIVEEITGYQTVNGVGERDSNSLNCDDCQFDGNSKQNSAGSYIPKDKTVAENGNSFAHSSLLLNSSKEDSVVDHYVPCTNSQEQVKLEDHKIISDCLPEEHANQADEPATGSFSEIQSSLLRDSEEEVDVVGDSSASKEQCAENTNNNPNTHRDSTSISGEPEPHSSVLDCVSAQMTSISELQEHRYTLRTSPRRAAPARSSPTKNNSPCRENGQVEENNLSPTEKNVPVGINNINGSPKNSEEIKQNEKERNCNTDNGSDGLRKPLSEARLVAGYVPSAKESANNHTAEDEEEEPDVYYFESDHVALKHNKDYQRLLQTIAVLEAQRTQAVQDLESLGRHQREALKDPIGFVERLQKKVDMGLPYPQRVVQLPEIAWDQYTSSLGNFEREFKNRKRNSRRAKLIFDKVGIPARPKSPLDPKKDGESISYSVLPLSDGPEGSTSSRPQMIRGRLCDETKPETFNQLWTVEEQKKLEQLLLKYPPEEVESRRWQKIADELGNRTAKQVASRVQKYFIKLTKAGIPVPGRTPNLYLYSKKSSSRRQHPLNKHLFKPSTFMTSHEPPVYMDEDDDRSSFHSHMDIAAEEEVSDEESIPITYRELPEYKELLEFKKLKRQKLQQMHAESGFVQHVGFKCDNCGIEPIQGVRWHCQDCPQEMSLDFCDSCSDCLHETEIHKEDHQLEPIYRAETFLDRDYCMSQGTSYNYLDPNYFPANR", "length": 905, "header": "tr|F1NID3-1|F1NID3_CHICK Isoform 1 of ZZ-type zinc finger-containing protein 3 OS=Gallus gallus OX=9031 GN=ZZZ3 PE=4 SV=2 CANONICAL=F1NID3-1" }, "isoforms": [ { "isoform_ac": "F1NID3-1", "url": "https://www.uniprot.org/uniprotkb/F1NID3/entry#F1NID3-1", "sequence": { "sequence": "MAASRSTRVTRSTVGLNGLDENFCGRTLRNRSIAHPEEVSPHPQVRSRSPKKRPDSVQTQKGSNGGRTTDLKQQSTRESWVSPRKRGLSTSEKDNVDKQTVENCEKRQGEPVSPVLKRIKRCLRSEAPNSSEEDLSTKTEKESLERKSLVSDNDAVSPGTKRACRCLILDDCDKREVKKVNICAEGFNNSAIVEEITGYQTVNGVGERDSNSLNCDDCQFDGNSKQNSAGSYIPKDKTVAENGNSFAHSSLLLNSSKEDSVVDHYVPCTNSQEQVKLEDHKIISDCLPEEHANQADEPATGSFSEIQSSLLRDSEEEVDVVGDSSASKEQCAENTNNNPNTHRDSTSISGEPEPHSSVLDCVSAQMTSISELQEHRYTLRTSPRRAAPARSSPTKNNSPCRENGQVEENNLSPTEKNVPVGINNINGSPKNSEEIKQNEKERNCNTDNGSDGLRKPLSEARLVAGYVPSAKESANNHTAEDEEEEPDVYYFESDHVALKHNKDYQRLLQTIAVLEAQRTQAVQDLESLGRHQREALKDPIGFVERLQKKVDMGLPYPQRVVQLPEIAWDQYTSSLGNFEREFKNRKRNSRRAKLIFDKVGIPARPKSPLDPKKDGESISYSVLPLSDGPEGSTSSRPQMIRGRLCDETKPETFNQLWTVEEQKKLEQLLLKYPPEEVESRRWQKIADELGNRTAKQVASRVQKYFIKLTKAGIPVPGRTPNLYLYSKKSSSRRQHPLNKHLFKPSTFMTSHEPPVYMDEDDDRSSFHSHMDIAAEEEVSDEESIPITYRELPEYKELLEFKKLKRQKLQQMHAESGFVQHVGFKCDNCGIEPIQGVRWHCQDCPQEMSLDFCDSCSDCLHETEIHKEDHQLEPIYRAETFLDRDYCMSQGTSYNYLDPNYFPANR", "length": 905, "header": "tr|F1NID3-1|F1NID3_CHICK Isoform 1 of ZZ-type zinc finger-containing protein 3 OS=Gallus gallus OX=9031 GN=ZZZ3 PE=4 SV=2 CANONICAL=F1NID3-1" }, "locus": { "chromosome": "8", "start_pos": 18765805, "end_pos": 18737966, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054381.1", "url": "https://www.ensembl.org/id/ENSGALT00010054381.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032851.1", "url": "https://www.ensembl.org/id/ENSGALP00010032851.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:424554", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424554", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2MIG4-1", "protein_name": "ZZ-type zinc finger-containing protein 3", "gene_name": "Zzz3", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MVGTCHSMAASRSTRVTRSTVGLNGLDESFCGRTLRNRSIAHPEEISSHSQVRSRSPKKRPEPVPIQKGSNNGRASEIKQQSAREAWVSPRKRRLSSSEKEDLERQGLESCERKQAEPAPPVLKNIKRCLRAEATNSSEEDSPVKPDKGSVEQRTVVDHDAEFQGTKRACRCLVLDDCEKREIKKMTVSEEGPLNTAIVEEITGYLTVNGVEDSDSALVNCEDCQPDGSTKHNSTGSYVLQEKSVAGNGDSETQTPMFFGSRKEDSCVDHLVPCTKSEVQVKLEDHKLATACLPVERRKPPTAEPASGPVSEIQSSLRDSEEEVDVVGDSSVSREQCDESGSGPLDSGTGSMPVSAEPEPASLLDCASAQMTSLAEPQEHRYTLRTSPRRAAPSRGSPTKTASPYRENGQFEESNLSPNETNTTASDNVSESPRNPVENAKVLCCDSQSYGSEGLSEPPSEARVNMGHVPSAKESASQPPAEEEDDDPDVYYFESDHVALKHNKDYQRLLQTIAVLEAQRCQAVQDLESLGKHQREALKNPIGFVEKLQKKADIGLPYPQRVVQLPEIVWDQYTNSLGNFEREFKNRKRHSRRVKLVFDKVGLPARPKSPLDLKKDGEPLSYSVLPLSDGPEGSHSRPQMIRGRLCDDTKPETFNQLWTVEEQKKLEELLLKYPPEEVESRRWQKIADELGNRTAKQVASRVQKYFIKLTKAGIPVPGRTPNLYMYSKKSSASRRQHPLNKHLFKPSTFMTSHEPPVYMDEDDDRSCFHGHTSPAVEEASDEESIPVMYRSLPEYKELLQFKKLKKQKLQQMQAESGFVQHVGFKCDNCGVEPIQGVRWHCQDCPPEMSLDFCDSCSDCPHETDIHKEDHQLEPVYKSETFLDRDYCVSQGTSYSYLDPNYFPANR", "length": 906 }, "evidence": [ { "id": "F1NID3", "url": "https://omabrowser.org/oma/group/F1NID3/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A5PMR0-1", "protein_name": "ZZ-type zinc finger-containing protein 3", "gene_name": "zzz3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAASRSSRVTRSSVGINGLDENFCGRTLRNRSIAQPEESSPPPVPRARSPKKKQDCQQHQQTGAQVGKVTESKAEGEPVPACGKRGLPSSEKEDSDKFDNCERQRSGCGPEASPALKRAKRCPRSGESQGAEEEPSLKPESPDPAVLKENDDGAKSNNTSASDKEADQKKDGPTEEIAPQPEVSENVKATNGLAELYREDSEVAALPVEPCASPATLNSSPSLLNGSQAAPSSPDPIVPCRSPHPKQTNEPDSPKIDCERNCTPEEAAEAVLSQEPEMEVEVDVVGEAGQAQDEFVREESTNGDFQAEPQDPSDNCSNISGETLLAASQLPAEPPSFTEPQEHRYTLRTSPRRAAFGSGLKASSPKPTSPHIDNGSLKEETTMVPFFSEDTSHKDPSHDALGLSCEADSELFEEEVVSGEVGVSDSRESRSTKELLAAQAEEDEEEEEDPDVYYFESDHLALKHNKDYQRLLQTISVLEAQRTQAILDLETLARHQKEALSDPIAFVDQLQKQVDMGLPRPQRVVQLPEIAWDQYTSGRGDFEREFCDKKRKTRQLQLIFDKVGLPARPKSPVDSKKEGESSSIYSSSLPSSDGPEHSMSSSRAQMIRGRLCNQSKPDTFNQLWTIEEQKKLEQLLLKFPPEEVESKRWQKIADELGNRTAKQVASRVQKYFIKLTKAGIPVPGRTPNVCMYSKKASSKRQHHLNKHLYRPSTFLTSYEPPVYMDDEDERSHFFNSLQDNSADDSDEDGVPVELRHLPEYKELLELKKLKKQKLHELQAESALTQHVGYKCDICGMEPIQGVRWHCQDCPQDNAVDFCSTCSDCLFRTDTHKPTHRLEPVCQAETFLDKDYCLPQSTGYNYLDPNYFPANR", "length": 871 }, "evidence": [ { "id": "F1NID3", "url": "https://omabrowser.org/oma/group/F1NID3/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1S9R4-1", "protein_name": "ZZ-type zinc finger-containing protein 3", "gene_name": "ZZZ3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAASRSTRVTRSTVGLNGLDESFCGRTLRNRSIAHPEEISSHSQVRSRSPKKRPEPVQVQKGNNNGRTTDVKQQSTRESWVSPRKRGLPSSEKDIIERQAVENCERRQTEPVSPVLKRIKRCLRSEAPNSSEEDSPIKSDKESVEQRSTVVDNDADFQGTKRACRCLILDDCEKREIKKVNVSEEGPLNSAVVEEITGYLAVNGVDDSDSAVINCDDCQPDGNTKQNSTGSYVLQEKSVAENGDSDTHTSMFLDGRKEDSYIDHNVPCTNSEVQVKLEDHKIVTACLPVEHVNQLTTEPATGPYSEIHSSLRDSEEEVDVVGDSSASKEQCNENTSNALDTSLESMPVSREPESSSVLDCVSAQMMSLSEPQEHRYTLRTSPRRAAPTRGSPTKNSSPCRENGPFEENNLNPNETNASVSDNISESLTNPDEISQNEKGICCGSENYGSEGLSKSSSEARLNIGHLPPAKESANPHATEEEDDDPDVYYFESDHVALKHNKDYQRLLQTIAVLEAQRSQAVQDLESLGRHQREALKNPIGFVEKLQKKADIGLPYPQRVVQLPEIVWDQYTNSLGNFEREFKNRKRHTRRVKLVFDKVGLPARPKSPLDSRKDGESLSYSMLPLSDGPEGSNSRPQMIRGRLCDDTKPETFNQLWTVEEQKKLEQLLLKYPPEEVESRRWQKIADELGNRTAKQVASRVQKYFIKLTKAGIPVPGRTPNLYIYSKKSSTSRRQHPLNKHLFKPSTFMTSHEPPVYMDEDDDRSCFHSHMSTAIEETSDEESIPIMYRNLPEYKELLQFKKLKKQKLQQMQAESGFVQHVGFKCDNCGIEPIQGVRWHCQDCPPEMSLDFCDSCSDCLHETDIHKEDHQLEPVYRSETFLDRDYCVSQGTSYNYLDPNYFPANR", "length": 903 }, "evidence": [ { "id": "F1NID3", "url": "https://omabrowser.org/oma/group/F1NID3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "M0R9X4-1", "protein_name": "ZZ-type zinc finger-containing protein 3", "gene_name": "Zzz3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVGTCHSMAASRSTRVTRSTVGLNGLDESFCGRTLRNRSIAHPEEISSHSQVRSRSPKKRPEPVPILKGNNNGRTSDVKQQSAREWVSPRKRRLSSSEKDDLERQALESCERRQAEPALPVLKNIKRCLRAEATNSSEEDSPVKPDKEPVEIRRTVVDHDAEFQGAKRACRCLILDDCEKREVKKVNVSEEGPLNAAVLEEITGYLTVNGVDDSDSAVINCDDCQPDRNTKQNSPGSCVLQEESVAGDGDSETQTSVFCGSGKEDSCIDHFVPCTKSDVQVKLEDHKLVTACLPVERRSQLTAESASGPVSEVQSSLRDSEEEVDVVGDSSASKEQCNENSSDPLDTGSECLPASGEPELSSMLDCVSAQMTSLSEPQEHRYTLRTSPRRAAQTRGSPTKNTSPYRENGQFEENNLSPNETNTTASDNVSESPTNPVEISQDEKVLCCDSENYGSEGLSKPSSEARMNIGHLPSAKESASQHTAEEEDDDPDVYYFESDHVALKHNKDYQRLLQTIAVLEAQRSQAVQDLESLGKHQREALKNPIGFVEKLQKKADIGLPYPQRVVQLPEIVWDQYTSSLGNFEREFKHRKRHTRRVKLVFDKVGLPARPKSPLDPKKDGDSLSYSMLPLSDGPEGSHHRPQMIRGRLCDDSKPETFNQLWTVEEQKKLEQLLLKYPPEEVESRRWQKIADELGNRTAKQVASRVQKYFIKLTKAGIPVPGRTPNLYIYSRKSSTSRRQHPLNKHLFKPSTFMTSHEPPVYMDEDDERSCPHSHMSTAVEEASDEESIPVIYRSLPEYKELLQFKKLKKQKLQQMQAESGFVQHVGFKCDNCGVEPIQGVRWHCQDCPPEMSLDFCDSCSDCPHETDIHKEDHQLEPVYKSETFLDRDYCVSQGTSYSYLDPNYFPANR", "length": 909 }, "evidence": [ { "id": "F1NID3", "url": "https://omabrowser.org/oma/group/F1NID3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6KAQ7-1", "protein_name": "ZZ-type zinc finger-containing protein 3", "gene_name": "Zzz3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVGTCHSMAASRSTRVTRSTVGLNGLDESFCGRTLRNRSIAHPEEISSHSQVRSRSPKKRAEPVPTQKGTNNGRTSDVRQQSARDSWVSPRKRRLSSSEKDDLERQALESCERRQAEPAPPVFKNIKRCLRAEATNSSEEDSPVKPDKEPGEHRRIVVDHDADFQGAKRACRCLILDDCEKREVKKVNVSEEGPLNAAVVEEITGYLTVNGVDDSDSAVINCDDCQPDGNTKQNNPGSCVLQEESVAGDGDSETQTSVFCGSRKEDSCIDHFVPCTKSDVQVKLEDHKLVTACLPVERRNQLTAESASGPVSEIQSSLRDSEEEVDVVGDSSASKEQCNENSSNPLDTGSERMPVSGEPELSSILDCVSAQMTSLSEPQEHRYTLRTSPRRAALARSSPTKTTSPYRENGQLEETNLSPQETNTTVSDHVSESPTDPAEVPQDGKVLCCDSENYGSEGLSKPPSEARVNIGHLPSAKESASQHTAEEEDDDPDVYYFESDHVALKHNKDYQRLLQTIAVLEAQRSQAVQDLESLGKHQREALKNPIGFVEKLQKKADIGLPYPQRVVQLPEIMWDQYTNSLGNFEREFKHRKRHTRRVKLVFDKVGLPARPKSPLDPKKDGESLSYSMLPLSDGPEGSHNRPQMIRGRLCDDSKPETFNQLWTVEEQKKLEQLLLKYPPEEVESRRWQKIADELGNRTAKQVASRVQKYFIKLTKAGIPVPGRTPNLYIYSRKSSTSRRQHPLNKHLFKPSTFMTSHEPPVYMDEDDDRSCLHSHMSTAAEEASDEESIPIIYRSLPEYKELLQFKKLKKQKLQQMQAESGFVQHVGFKCDNCGVEPIQGVRWHCQDCPPEMSLDFCDSCSDCPHETDIHKEDHQLEPVYKSETFLDRDYCVSQGTSYSYLDPNYFPANR", "length": 910 }, "evidence": [ { "id": "F1NID3", "url": "https://omabrowser.org/oma/group/F1NID3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8IYH5-1", "protein_name": "ZZ-type zinc finger-containing protein 3", "gene_name": "ZZZ3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAASRSTRVTRSTVGLNGLDESFCGRTLRNRSIAHPEEISSNSQVRSRSPKKRPEPVPIQKGNNNGRTTDLKQQSTRESWVSPRKRGLSSSEKDNIERQAIENCERRQTEPVSPVLKRIKRCLRSEAPNSSEEDSPIKSDKESVEQRSTVVDNDADFQGTKRACRCLILDDCEKREIKKVNVSEEGPLNSAVVEEITGYLAVNGVDDSDSAVINCDDCQPDGNTKQNSIGSYVLQEKSVAENGDTDTQTSMFLDSRKEDSYIDHKVPCTDSQVQVKLEDHKIVTACLPVEHVNQLTTEPATGPFSETQSSLRDSEEEVDVVGDSSASKEQCKENTNNELDTSLESMPASGEPEPSPVLDCVSAQMMSLSEPQEHRYTLRTSPRRAAPTRGSPTKNSSPYRENGQFEENNLSPNETNATVSDNVSQSPTNPGEISQNEKGICCDSQNNGSEGVSKPPSEARLNIGHLPSAKESASQHITEEEDDDPDVYYFESDHVALKHNKDYQRLLQTIAVLEAQRSQAVQDLESLGRHQREALKNPIGFVEKLQKKADIGLPYPQRVVQLPEIVWDQYTHSLGNFEREFKNRKRHTRRVKLVFDKVGLPARPKSPLDPKKDGESLSYSMLPLSDGPEGSSSRPQMIRGRLCDDTKPETFNQLWTVEEQKKLEQLLIKYPPEEVESRRWQKIADELGNRTAKQVASRVQKYFIKLTKAGIPVPGRTPNLYIYSKKSSTSRRQHPLNKHLFKPSTFMTSHEPPVYMDEDDDRSCFHSHMNTAVEDASDDESIPIMYRNLPEYKELLQFKKLKKQKLQQMQAESGFVQHVGFKCDNCGIEPIQGVRWHCQDCPPEMSLDFCDSCSDCLHETDIHKEDHQLEPIYRSETFLDRDYCVSQGTSYNYLDPNYFPANR", "length": 903 }, "evidence": [ { "id": "F1NID3", "url": "https://omabrowser.org/oma/group/F1NID3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "F1NID3", "url": "https://www.uniprot.org/uniprotkb/F1NID3" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "F1NID3", "url": "https://www.uniprot.org/uniprotkb/F1NID3" } ], "pmid": "" }, { "name": "histone binding", "id": "GO:0042393", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042393", "evidence": [ { "database": "UniProtKB", "id": "F1NID3", "url": "https://www.uniprot.org/uniprotkb/F1NID3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "F1NID3", "url": "https://www.uniprot.org/uniprotkb/F1NID3" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "F1NID3", "url": "https://www.uniprot.org/uniprotkb/F1NID3" } ], "pmid": "" }, { "name": "ATAC complex", "id": "GO:0140672", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140672", "evidence": [ { "database": "UniProtKB", "id": "F1NID3", "url": "https://www.uniprot.org/uniprotkb/F1NID3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "F1NID3", "url": "https://www.uniprot.org/uniprotkb/F1NID3" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "F1NID3", "url": "https://www.uniprot.org/uniprotkb/F1NID3" } ], "pmid": "" }, { "name": "chromatin organization", "id": "GO:0006325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006325", "evidence": [ { "database": "UniProtKB", "id": "F1NID3", "url": "https://www.uniprot.org/uniprotkb/F1NID3" } ], "pmid": "" }, { "name": "regulation of cell cycle", "id": "GO:0051726", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051726", "evidence": [ { "database": "UniProtKB", "id": "F1NID3", "url": "https://www.uniprot.org/uniprotkb/F1NID3" } ], "pmid": "" }, { "name": "regulation of embryonic development", "id": "GO:0045995", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045995", "evidence": [ { "database": "UniProtKB", "id": "F1NID3", "url": "https://www.uniprot.org/uniprotkb/F1NID3" } ], "pmid": "" }, { "name": "regulation of cell division", "id": "GO:0051302", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051302", "evidence": [ { "database": "UniProtKB", "id": "F1NID3", "url": "https://www.uniprot.org/uniprotkb/F1NID3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 129, "end_pos": 131, "annotation": "n_glycosylation_sequon" }, { "start_pos": 188, "end_pos": 190, "annotation": "n_glycosylation_sequon" }, { "start_pos": 254, "end_pos": 256, "annotation": "n_glycosylation_sequon" }, { "start_pos": 30, "end_pos": 32, "annotation": "n_glycosylation_sequon" }, { "start_pos": 396, "end_pos": 398, "annotation": "n_glycosylation_sequon" }, { "start_pos": 410, "end_pos": 412, "annotation": "n_glycosylation_sequon" }, { "start_pos": 426, "end_pos": 428, "annotation": "n_glycosylation_sequon" }, { "start_pos": 448, "end_pos": 450, "annotation": "n_glycosylation_sequon" }, { "start_pos": 476, "end_pos": 478, "annotation": "n_glycosylation_sequon" }, { "start_pos": 691, "end_pos": 693, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1NID3-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 905, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1NID3-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1NID3" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 129, "end_pos": 131 }, { "start_pos": 188, "end_pos": 190 }, { "start_pos": 254, "end_pos": 256 }, { "start_pos": 30, "end_pos": 32 }, { "start_pos": 396, "end_pos": 398 }, { "start_pos": 410, "end_pos": 412 }, { "start_pos": 426, "end_pos": 428 }, { "start_pos": 448, "end_pos": 450 }, { "start_pos": 476, "end_pos": 478 }, { "start_pos": 691, "end_pos": 693 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1NIE0-1", "uniprot_ac": "F1NIE0", "uniprot_id": "F1NIE0_CHICK", "mass": { "chemical_mass": 40600.0, "monoisotopic_mass": 40600.0 }, "refseq": { "ac": "NP_001357692", "name": "lysophosphatidic acid receptor 6-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001357692" }, "gene_names": [ { "name": "LOC114977882", "type": "recommended", "evidence": [ { "id": "F1NIE0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NIE0" } ] }, { "name": "GPR205A", "type": "synonym", "evidence": [ { "id": "NP_001357692", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001357692" } ] }, { "name": "LOC114977882", "type": "synonym", "evidence": [ { "id": "NP_001357692", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001357692" } ] } ], "protein_names": [ { "name": "G-protein coupled receptors family 1 profile domain-containing protein", "type": "recommended", "evidence": [ { "id": "F1NIE0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NIE0/entry#names_and_taxonomy" } ] }, { "name": "G protein-coupled receptor 205A", "type": "synonym", "evidence": [ { "id": "NP_001357692", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001357692" } ] }, { "name": "lysophosphatidic acid receptor 6-like", "type": "synonym", "evidence": [ { "id": "NP_001357692", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001357692" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NIE0", "url": "https://www.uniprot.org/uniprotkb/F1NIE0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LOC114977882", "url": "https://www.uniprot.org/uniprotkb/F1NIE0", "locus": {} } ], "crossref": [ { "id": "ENSGALG00000001701", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000001701", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd14982", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14982", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "114977882", "url": "https://www.ncbi.nlm.nih.gov/gene/114977882", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047160", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047160", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "TTSHCKW", "url": "https://omabrowser.org/oma/group/TTSHCKW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1NIE0", "url": "https://www.orthodb.org/?gene=F1NIE0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24237", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24237", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24237:SF37", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24237:SF37", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00001", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00001", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001357692", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001357692", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1NIE0", "url": "https://www.uniprot.org/uniprotkb/F1NIE0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NIE0-1", "url": "https://www.uniprot.org/uniprotkb/F1NIE0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MANVSWTEGVSNGTAVRLEADFQYSLFTIIYSIVFVLGLTENVSALYLLSNKARHTSPSYVYMINLALADTLFVCGLPFKIHYHLNRNNWIFGDVACRITGTLYYINIYLSIVFFTCICVDRYIAVLHPFTYIQIRVTHYVVVATILWVVALSTTVALVLGGPLHNKGLRNTTMCFENFARSSWISRMALYNILALVFGFVIPFSIILICYPLIARRISRIKHSIRKRKALTTIYIILLICTFCFLPYHLTHFLHFLMRSQVIQNKSFTNLIYKMRRVTLALVSFNCCLNPFLYYFTSSNRTWHFNFRFRFRSKMVYTICDQKLGEYSYIYKLHQSCENKKQRDRIN", "length": 347, "header": "tr|F1NIE0-1|F1NIE0_CHICK Isoform 1 of G-protein coupled receptors family 1 profile domain-containing protein OS=Gallus gallus OX=9031 GN=LOC114977882 PE=4 SV=3 CANONICAL=F1NIE0-1" }, "isoforms": [ { "isoform_ac": "F1NIE0-1", "url": "https://www.uniprot.org/uniprotkb/F1NIE0/entry#F1NIE0-1", "sequence": { "sequence": "MANVSWTEGVSNGTAVRLEADFQYSLFTIIYSIVFVLGLTENVSALYLLSNKARHTSPSYVYMINLALADTLFVCGLPFKIHYHLNRNNWIFGDVACRITGTLYYINIYLSIVFFTCICVDRYIAVLHPFTYIQIRVTHYVVVATILWVVALSTTVALVLGGPLHNKGLRNTTMCFENFARSSWISRMALYNILALVFGFVIPFSIILICYPLIARRISRIKHSIRKRKALTTIYIILLICTFCFLPYHLTHFLHFLMRSQVIQNKSFTNLIYKMRRVTLALVSFNCCLNPFLYYFTSSNRTWHFNFRFRFRSKMVYTICDQKLGEYSYIYKLHQSCENKKQRDRIN", "length": 347, "header": "tr|F1NIE0-1|F1NIE0_CHICK Isoform 1 of G-protein coupled receptors family 1 profile domain-containing protein OS=Gallus gallus OX=9031 GN=LOC114977882 PE=4 SV=3 CANONICAL=F1NIE0-1" }, "locus": { "chromosome": "21", "start_pos": 2342888, "end_pos": 2342815, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043902.1", "url": "https://www.ensembl.org/id/ENSGALT00010043902.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026112.1", "url": "https://www.ensembl.org/id/ENSGALP00010026112.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "oxysterol binding", "id": "GO:0008142", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008142", "evidence": [ { "database": "UniProtKB", "id": "F1NIE0", "url": "https://www.uniprot.org/uniprotkb/F1NIE0" } ], "pmid": "" }, { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "F1NIE0", "url": "https://www.uniprot.org/uniprotkb/F1NIE0" } ], "pmid": "" }, { "name": "signaling receptor activity", "id": "GO:0038023", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038023", "evidence": [ { "database": "UniProtKB", "id": "F1NIE0", "url": "https://www.uniprot.org/uniprotkb/F1NIE0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F1NIE0", "url": "https://www.uniprot.org/uniprotkb/F1NIE0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "G protein-coupled receptor signaling pathway", "id": "GO:0007186", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007186", "evidence": [ { "database": "UniProtKB", "id": "F1NIE0", "url": "https://www.uniprot.org/uniprotkb/F1NIE0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 12, "end_pos": 14, "annotation": "n_glycosylation_sequon" }, { "start_pos": 171, "end_pos": 173, "annotation": "n_glycosylation_sequon" }, { "start_pos": 265, "end_pos": 267, "annotation": "n_glycosylation_sequon" }, { "start_pos": 300, "end_pos": 302, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3, "end_pos": 5, "annotation": "n_glycosylation_sequon" }, { "start_pos": 42, "end_pos": 44, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1NIE0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NIE0" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 41, "end_pos": 294, "start_aa": "Glu", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 12, "end_pos": 14 }, { "start_pos": 171, "end_pos": 173 }, { "start_pos": 265, "end_pos": 267 }, { "start_pos": 300, "end_pos": 302 }, { "start_pos": 3, "end_pos": 5 }, { "start_pos": 42, "end_pos": 44 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1NIE6-1", "uniprot_ac": "F1NIE6", "uniprot_id": "F1NIE6_CHICK", "mass": { "chemical_mass": 53231.0, "monoisotopic_mass": 53231.0 }, "refseq": {}, "gene_names": [ { "name": "B3GNT9", "type": "recommended", "evidence": [ { "id": "F1NIE6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NIE6" } ] } ], "protein_names": [ { "name": "Hexosyltransferase", "type": "recommended", "evidence": [ { "id": "F1NIE6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NIE6/entry#names_and_taxonomy" } ] }, { "name": "2.4.1.-", "type": "synonym", "evidence": [ { "id": "F1NIE6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NIE6/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NIE6", "url": "https://www.uniprot.org/uniprotkb/F1NIE6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "B3GNT9", "url": "https://www.uniprot.org/uniprotkb/F1NIE6", "locus": { "chromosome": "11", "start_pos": 2451655, "end_pos": 2460720, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010024434", "url": "https://www.ensembl.org/id/ENSGALG00010024434" } ] } } ], "crossref": [ { "id": "F1NIE6", "url": "https://alphafold.ebi.ac.uk/entry/F1NIE6", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000021345", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000021345", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR002659", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002659", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZSF2", "url": "https://www.orthodb.org/?gene=A0A8V0ZSF2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NIE6", "url": "https://www.orthodb.org/?gene=F1NIE6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11214", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11214", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11214:SF91", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11214:SF91", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01762", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01762", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-913709", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-913709", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0ZSF2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSF2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZSF2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSF2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NIE6", "url": "https://www.uniprot.org/uniprotkb/F1NIE6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NIE6-1", "url": "https://www.uniprot.org/uniprotkb/F1NIE6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSPANYIQMCLPGSPLPGQYRGDPGSALSNGIWTLVPDSSATAFSSPRKTTGTMRVHLKGDAICTLFLVVALCSVLYTQLEYLAPKGDKQPTQKKPSVTQRIFSDPRAPGRPTVTEATVPRPRLIPITRRTEVANSKVQTATPVPSTDSAFNFKRYFLNKDNRNFNLLINQPKKCRRIPGGPFLLIAIKSVVEDFDRREIVRKTWGREGLVNGEQIQRVFLLGTPKNRTSLATWETLMHQESQTYRDILLWDFMDTFFNLTLKEIHFLNWAAEFCHNVKFIFKGDADVFVNIENIVDFLERHNPAEDLFVGDIIYNARPIRTRKSKYYIPETMYGLSIYPAYAGGGGFLLSSCTMRKLSRACGEVELFPIDDVFLGMCLQRISLKPILHEGFKTFGIVKPSAAPHLQTFDPCFYKDLMVVHSLKVAEIWLMWNLLHSPRLSCTQKRQVKKPFQWKRRAQIATQTSPLS", "length": 468, "header": "tr|F1NIE6-1|F1NIE6_CHICK Isoform 1 of Hexosyltransferase OS=Gallus gallus OX=9031 GN=B3GNT9 PE=3 SV=5 CANONICAL=F1NIE6-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZSF2-1", "url": "https://www.uniprot.org/uniprotkb/F1NIE6/entry#A0A8V0ZSF2-1", "sequence": { "sequence": "MGYRRSLGRVWTLVPDSSATAFSSPRKTTGTMRVHLKGDAICTLFLVVALCSVLYTQLEYLAPKGDKQPTQKKPSVTQRIFSDPRAPGRPTVTEATVPRPRLIPITRRTEVANSKVQTATPVPSTDSAFNFKRYFLNKDNRNFNLLINQPKKCRRIPGGPFLLIAIKSVVEDFDRREIVRKTWGREGLVNGEQIQRVFLLGTPKNRTSLATWETLMHQESQTYRDILLWDFMDTFFNLTLKEIHFLNWAAEFCHNVKFIFKGDADVFVNIENIVDFLERHNPAEDLFVGDIIYNARPIRTRKSKYYIPETMYGLSIYPAYAGGGGFLLSSCTMRKLSRACGEVELFPIDDVFLGMCLQRISLKPILHEGFKTFGIVKPSAAPHLQTFDPCFYKDLMVVHSLKVAEIWLMWNLLHSPRLSCTQKRQVKKPFQWKRRAQIATQTSPLS", "length": 446, "header": "tr|A0A8V0ZSF2-1|A0A8V0ZSF2_CHICK Computationally mapped isoform of Hexosyltransferase OS=Gallus gallus OX=9031 GN=B3GNT9 PE=3 SV=1 CANONICAL=F1NIE6-1" }, "locus": { "chromosome": "11", "start_pos": 2460398, "end_pos": 2453619, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010059619.1", "url": "https://www.ensembl.org/id/ENSGALT00010059619.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010036414.1", "url": "https://www.ensembl.org/id/ENSGALP00010036414.1" } ] } }, { "isoform_ac": "F1NIE6-1", "url": "https://www.uniprot.org/uniprotkb/F1NIE6/entry#F1NIE6-1", "sequence": { "sequence": "MSPANYIQMCLPGSPLPGQYRGDPGSALSNGIWTLVPDSSATAFSSPRKTTGTMRVHLKGDAICTLFLVVALCSVLYTQLEYLAPKGDKQPTQKKPSVTQRIFSDPRAPGRPTVTEATVPRPRLIPITRRTEVANSKVQTATPVPSTDSAFNFKRYFLNKDNRNFNLLINQPKKCRRIPGGPFLLIAIKSVVEDFDRREIVRKTWGREGLVNGEQIQRVFLLGTPKNRTSLATWETLMHQESQTYRDILLWDFMDTFFNLTLKEIHFLNWAAEFCHNVKFIFKGDADVFVNIENIVDFLERHNPAEDLFVGDIIYNARPIRTRKSKYYIPETMYGLSIYPAYAGGGGFLLSSCTMRKLSRACGEVELFPIDDVFLGMCLQRISLKPILHEGFKTFGIVKPSAAPHLQTFDPCFYKDLMVVHSLKVAEIWLMWNLLHSPRLSCTQKRQVKKPFQWKRRAQIATQTSPLS", "length": 468, "header": "tr|F1NIE6-1|F1NIE6_CHICK Isoform 1 of Hexosyltransferase OS=Gallus gallus OX=9031 GN=B3GNT9 PE=3 SV=5 CANONICAL=F1NIE6-1" }, "locus": { "chromosome": "11", "start_pos": 2460486, "end_pos": 2453619, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010059617.1", "url": "https://www.ensembl.org/id/ENSGALT00010059617.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010036412.1", "url": "https://www.ensembl.org/id/ENSGALP00010036412.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "R-GGA-913709", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-913709", "resource": "Reactome", "description": "O-linked glycosylation of mucins" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "UDP-glycosyltransferase activity", "id": "GO:0008194", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008194", "evidence": [ { "database": "UniProtKB", "id": "F1NIE6", "url": "https://www.uniprot.org/uniprotkb/F1NIE6" } ], "pmid": "" }, { "name": "hexosyltransferase activity", "id": "GO:0016758", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016758", "evidence": [ { "database": "UniProtKB", "id": "F1NIE6", "url": "https://www.uniprot.org/uniprotkb/F1NIE6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "F1NIE6", "url": "https://www.uniprot.org/uniprotkb/F1NIE6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "glycoprotein biosynthetic process", "id": "GO:0009101", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009101", "evidence": [ { "database": "UniProtKB", "id": "F1NIE6", "url": "https://www.uniprot.org/uniprotkb/F1NIE6" } ], "pmid": "" }, { "name": "poly-N-acetyllactosamine biosynthetic process", "id": "GO:0030311", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030311", "evidence": [ { "database": "UniProtKB", "id": "F1NIE6", "url": "https://www.uniprot.org/uniprotkb/F1NIE6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 227, "end_pos": 229, "annotation": "n_glycosylation_sequon" }, { "start_pos": 259, "end_pos": 261, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-GGA-914010", "name": "B3GNT6 transfers GlcNAc to Tn antigen", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "Golgi lumen, Golgi membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V1ACG2-1", "F1NIE6-1", "A0A1D5PGR9-1", "A0A8V1A7T7-1", "A0A8V0YSJ1-1" ], "evidence": [ { "id": "R-GGA-914010", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-914010" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A1D5PGR9", "gene_name": "B3GNT5", "activity": [ { "ec_number": "2.4.1.-", "activity": "", "evidence": [ { "id": "A0A1D5PGR9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PGR9" } ] } ] }, { "uniprot_ac": "A0A8V0YSJ1", "gene_name": "B3GNT7", "activity": [ { "ec_number": "2.4.1.-", "activity": "", "evidence": [ { "id": "A0A8V0YSJ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSJ1" } ] } ] }, { "uniprot_ac": "A0A8V1A7T7", "gene_name": "B3GNT4", "activity": [ { "ec_number": "2.4.1.-", "activity": "", "evidence": [ { "id": "A0A8V1A7T7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7T7" } ] } ] }, { "uniprot_ac": "A0A8V1ACG2", "gene_name": "B3GNT3", "activity": [ { "ec_number": "2.4.1.-", "activity": "", "evidence": [ { "id": "A0A8V1ACG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACG2" } ] } ] }, { "uniprot_ac": "F1NIE6", "gene_name": "B3GNT9", "activity": [ { "ec_number": "2.4.1.-", "activity": "", "evidence": [ { "id": "F1NIE6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NIE6" } ] } ] } ], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1NIE6-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 468, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1NIE6-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1NIE6" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 227, "end_pos": 229 }, { "start_pos": 259, "end_pos": 261 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1NIH1-1", "uniprot_ac": "F1NIH1", "uniprot_id": "F1NIH1_CHICK", "mass": { "chemical_mass": 54674.0, "monoisotopic_mass": 54674.0 }, "refseq": { "ac": "XP_415494", "name": "cytoplasmic dynein 2 intermediate chain 2 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_415494" }, "gene_names": [ { "name": "WDR34", "type": "recommended", "evidence": [ { "id": "F1NIH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NIH1" } ] }, { "name": "WDR34", "type": "synonym", "evidence": [ { "id": "XP_415494", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_415494" } ] } ], "protein_names": [ { "name": "Dynein 2 intermediate chain 2", "type": "synonym", "evidence": [ { "id": "F1NIH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NIH1/entry#names_and_taxonomy" } ] }, { "name": "cytoplasmic dynein 2 intermediate chain 2 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_415494", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_415494" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052548.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Nov 16, 2006 this sequence version replaced XP_415494.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_415494", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_415494" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NIH1", "url": "https://www.uniprot.org/uniprotkb/F1NIH1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "WDR34", "url": "https://www.uniprot.org/uniprotkb/F1NIH1", "locus": {} } ], "crossref": [ { "id": "F1NIH1", "url": "https://alphafold.ebi.ac.uk/entry/F1NIH1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000004702", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000004702", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "417211", "url": "https://www.ncbi.nlm.nih.gov/gene/417211", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001680", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001680", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036322", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036322", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050687", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050687", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:417211", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417211", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "SYVCAWN", "url": "https://omabrowser.org/oma/group/SYVCAWN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1NIH1", "url": "https://www.orthodb.org/?gene=F1NIH1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12442", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12442", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12442:SF26", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12442:SF26", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00400", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00400", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-5620924", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5620924", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_415494", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_415494", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1NIH1", "url": "https://www.uniprot.org/uniprotkb/F1NIH1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NIH1-1", "url": "https://www.uniprot.org/uniprotkb/F1NIH1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MFADETVPGAAVQSLWRSARNARCEAKSCQTAEVATAEAAVQSRSSRDAAVQTDRSAARDVHHGARVDDSGVLAFLRRVEEVVTKELNKNVTSRAFDGFDVNWTDQNRTVLCLHTLSYPEAQDQHLQVTGVSWNATGSVVACSYGRLNDGDWSTEKSYVCTWNLDRRRLDPQRPDLVVDAPSSVMCLAFHPSQPSLIAGGLFSGETVVWDTSKPEDPLIWRTGMTDDTHTDPVSQVHWLSDAKHGNHIQLLSASTDGKILVWREERDGRLAVAEGFALVAQQIPRSARLKKLAWGEAAVGVTSLSFSHFDPHVFIVGVEGGYSLKCSTAADTPAPRRTGGSVPLRAPAELAFSPHSGPLYSVSCSPFHRNLFLSCGTDGQVHLSSMLQTQPLISLQLSTKYLFCVRWSPVRPLVFAVASGEGDVHLVDFEKSSQKPAVSIKQAVDECPVYCLEFNSKQTQLLAAGDAAGTVKVWQLSSDFTEQRPREMNHLELLASELTD", "length": 500, "header": "tr|F1NIH1-1|F1NIH1_CHICK Isoform 1 of Dynein 2 intermediate chain 2 OS=Gallus gallus OX=9031 GN=WDR34 PE=1 SV=2 CANONICAL=F1NIH1-1" }, "isoforms": [ { "isoform_ac": "F1NIH1-1", "url": "https://www.uniprot.org/uniprotkb/F1NIH1/entry#F1NIH1-1", "sequence": { "sequence": "MFADETVPGAAVQSLWRSARNARCEAKSCQTAEVATAEAAVQSRSSRDAAVQTDRSAARDVHHGARVDDSGVLAFLRRVEEVVTKELNKNVTSRAFDGFDVNWTDQNRTVLCLHTLSYPEAQDQHLQVTGVSWNATGSVVACSYGRLNDGDWSTEKSYVCTWNLDRRRLDPQRPDLVVDAPSSVMCLAFHPSQPSLIAGGLFSGETVVWDTSKPEDPLIWRTGMTDDTHTDPVSQVHWLSDAKHGNHIQLLSASTDGKILVWREERDGRLAVAEGFALVAQQIPRSARLKKLAWGEAAVGVTSLSFSHFDPHVFIVGVEGGYSLKCSTAADTPAPRRTGGSVPLRAPAELAFSPHSGPLYSVSCSPFHRNLFLSCGTDGQVHLSSMLQTQPLISLQLSTKYLFCVRWSPVRPLVFAVASGEGDVHLVDFEKSSQKPAVSIKQAVDECPVYCLEFNSKQTQLLAAGDAAGTVKVWQLSSDFTEQRPREMNHLELLASELTD", "length": 500, "header": "tr|F1NIH1-1|F1NIH1_CHICK Isoform 1 of Dynein 2 intermediate chain 2 OS=Gallus gallus OX=9031 GN=WDR34 PE=1 SV=2 CANONICAL=F1NIH1-1" }, "locus": { "chromosome": "17", "start_pos": 5868893, "end_pos": 5861181, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069177.1", "url": "https://www.ensembl.org/id/ENSGALT00010069177.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042619.1", "url": "https://www.ensembl.org/id/ENSGALP00010042619.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:417211", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417211", "resource": "KEGG Pathway" }, { "id": "R-GGA-5620924", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5620924", "resource": "Reactome", "description": "Intraflagellar transport" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2QC64-1", "protein_name": "Cytoplasmic dynein 2 intermediate chain 2", "gene_name": "Dync2i2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAISASPRPFPRVGSARVAALAAGGAGGGERRGRPAPLQDETLGVASVPSQWRSVQGIRGEPKSCQTAGIATAEASAQARTHADAQVQTEAPEEPAAVAPVSQYDTLRLAAFLRRVEAMVVRELNNNWQSHAFDGYEVNWTEQQQTVSCLHTLGYPPAQGQGLHVTGISWNTTGSVLACAYGRLDDGDWGTLKSYVCTWNLDRQGLNPHQPSVVVEVPSAVMCLAFHPIQPSHIAGGLYSGEVLVWDMSRPEDPLLWRTGLTDDTHTDPVYQVLWLPEPRHSHRFQVLSAATDGRVLLWRGSGAGQLRLSKGFALAVQQLPRSTKLKKPPRGETEVGVTSVAFSSFDSSLFVLGTEGGFPLKCSLAAEAAALTRMPSSVPLRAPVQFTFSPHGGPVYSVSCSPFHRNLFLSAGTDGHVHLYSMLQAQPLTSLQLSHKYLFAVRWSPVRPLVFAAASGEGDVQLFDLQKSSQKPTVSITQTQDGSPVYCLEFNSQQTQLLAAGDAKGVVKVWQLSTAFTEQGPREAEDLDQLEAEIAT", "length": 537 }, "evidence": [ { "id": "F1NIH1", "url": "https://omabrowser.org/oma/group/F1NIH1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8C2QKU9-1", "protein_name": "Cytoplasmic dynein 2 intermediate chain 2", "gene_name": "Dync2i2", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAMRASPGPFRRAGSARAATLAAGGAGGAERPGRSAPLQDETLGVASVPSQWRGVQGIRGETKSCQTASIATAEASVQARTQVDAQVQTEAPEPVAPVPVSQPDTLRLAAFLRRVEATVIRELNNNWQSHAFDGYEVNWTEPQQTVSCLHTLVYPPAQGQGLHVTGISWNATGSVLACAYGRLDDGDWSTLKSYVCTWNLDRQGLNPQQPSAVVEVPSAVMCLAFHPTQPSHIAGGLYSGEVLVWDMSRPEDPLLWRTGLTDDTHTDPVYQVLWLPEPRHSHRFQVLSASTDGRVLLWRGSGAGQLRLSKGFALAVQQLPRSTKLKKPPRGETEVGVTSVAFSSFDSSLFVLGTEGGFPLKCSLAAEAAALTRMPSSVPLRAPVQFTFSPHGGPVYSVSCSPFHRNLFLSAGTDGHVHLYSMLQAQPLTSLQLSHKYLFAVRWSPVRPLVFAAASGEGDVQLFDLQKSSQKPTVSITQTQDGSPVYCLEFNSQQTQLLAAGDAKGMVKVWQLSTAFTEQGPRETEDLDQLEAEVAT", "length": 536 }, "evidence": [ { "id": "F1NIH1", "url": "https://omabrowser.org/oma/group/F1NIH1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "F1MTS5-1", "protein_name": "Cytoplasmic dynein 2 intermediate chain 2", "gene_name": "DYNC2I2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MATSAQPWQLGLAGSAGAEALATSGTSSTEGPERPGPLQDETLGVASVPSQWRGVQGIRGETKSCQTASIATAEASVQARKHVDAEVQTEAPEPVSLPSVPRYNGPQLAAFLRKVEAMVTRELNKNWQSHAFDGFEVNWAEQQQTVNCLHTLSYPPAQGQGLHVTGVSWNSTGSVVACAYGRLDDGDWSTLRSFVCAWNLDRRGLSPQQPSAVVEVPSAAMCLAFHPTRPSHVAGGLYSGEVLVWDMSRPEDPLLWRTGLTDDTHTDPVYQVVWLPEPRHSHRFQVLSVAADGKVLLWQGVGAGRLQLSAGFALAVQQLPRNTKLKKPSRGEAEVGATAVAFSSFDPSLFVLGTEGGFPLKCSLSAEEAAVTRMPSSVPLRAPAQFTFAPHGGPVYSVSCSPFHRNLFLSAGTDGHAHLYSMLQAQPLTSLQLSHKYLFAVRWSPVRPLVFAAASGEGDVQLFDLQKSSQKPTVSVKQTEDESPVYCLEFNCQQTQLLAAGDAKGTVKVWQLSSEFTEQGARETELLDQLASEVAS", "length": 536 }, "evidence": [ { "id": "F1NIH1", "url": "https://omabrowser.org/oma/group/F1NIH1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1RR77-1", "protein_name": "Cytoplasmic dynein 2 intermediate chain 2", "gene_name": "DYNC2I2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MATCALRGQLFPAGRAGAEALATRGIASPEGPERPGPLQDETLGVASVPSQWRTVQGIRGETKSCQTASIATTEVSAQTWKHADAEVQTEAPEPVSVPSSVSWSDGPGLAAFLRRVEPMVTRELNKNWQSHAFDGFEVNWAEQQPTVTCLHTLGYPPAQAQGLHVTSVSWNTTGSVVGCAYGRLDDGDWSTLKSFVCAWNLDRRGLKPQQPSAVVEVPSAVMCLAFHPTQPAHVAGGLYSGEVLVWDLSRPEDPLLWRTGLTDDTHTDPVYQVLWLPEPRHSQRFQVLSAAADGKVLLWQGGTGGRLRLSAGFALAVQQLPRNTKLKKPPRGETEVGATAVAFSSFDSSLFVLGTEGGFPLKCSLAAAEAALTRMPSSVPLRAPAQFTFSPHGGPVYSVSCSPFHRNLFLSAGTDGHVHLYSMLQAPPLASLRLTHKYLFAVRWSPVRPLVFAAASGEGEVQLFDLQKSSQKPTVSVKQTQDERPVYCLEFNCQQTQLLAAGDAQGTVKVWRLSTEFTEQGPREREDLDQLAAEVAT", "length": 537 }, "evidence": [ { "id": "F1NIH1", "url": "https://omabrowser.org/oma/group/F1NIH1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q5U4F6-1", "protein_name": "Cytoplasmic dynein 2 intermediate chain 2", "gene_name": "Dync2i2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAMCASPRPFRRVGSAGAAALAAGGAGGAERRGRPAPLQDETLGVASVPSQWRSVQGIRGETKSCQTAGIATAESSAQARTHADAQVQTEAPEEPAAMAPVSQYDTLRLEAFLRRVEAMVIRELNNNWQSHAFDGYEVNWTEQQQTVSCLHTLVYPLAQGQGLHVTGISWNSTGSVLACAYGRLDDGDWSTLKSYVCTWNLDRQGLNPQQPSVVVEVPSAVMCLAFHPTQPSHIAGGLYSGEVLVWDMSRPEDPLLWRTGLTDDTHTDPVYQVLWLPEPRHSHRFQVLSAATDGKVLLWRGSGAGQLRLTKGFALAVQQLPRSTKLKKPPRGETEVGVTSVAFSSFDSSLFVLGTEGGFPLKCSLASEVAALTRMPSSVPLRAPVQFTFSPHGGPVYSVSCSPFHRNLFLSAGTDGHVHLYSMLQAQPLTSLQLSHKYLFAVRWSPVRPLVFAAASGEGDVQLFDLQKSSQKPTVSITQTQDGSPVYCLEFNSQQTQLLAAGDAKGMVKVWQLSTAFTEQGPREVEDLDQLEAEITT", "length": 537 }, "evidence": [ { "id": "F1NIH1", "url": "https://omabrowser.org/oma/group/F1NIH1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96EX3-1", "protein_name": "Cytoplasmic dynein 2 intermediate chain 2", "gene_name": "DYNC2I2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MATRAQPGPLSQAGSAGVAALATVGVASGPGPGRPGPLQDETLGVASVPSQWRAVQGIRWETKSCQTASIATASASAQARNHVDAQVQTEAPVPVSVQPPSQYDIPRLAAFLRRVEAMVIRELNKNWQSHAFDGFEVNWTEQQQMVSCLYTLGYPPAQAQGLHVTSISWNSTGSVVACAYGRLDHGDWSTLKSFVCAWNLDRRDLRPQQPSAVVEVPSAVLCLAFHPTQPSHVAGGLYSGEVLVWDLSRLEDPLLWRTGLTDDTHTDPVSQVVWLPEPGHSHRFQVLSVATDGKVLLWQGIGVGQLQLTEGFALVMQQLPRSTKLKKHPRGETEVGATAVAFSSFDPRLFILGTEGGFPLKCSLAAGEAALTRMPSSVPLRAPAQFTFSPHGGPIYSVSCSPFHRNLFLSAGTDGHVHLYSMLQAPPLTSLQLSLKYLFAVRWSPVRPLVFAAASGKGDVQLFDLQKSSQKPTVLIKQTQDESPVYCLEFNSQQTQLLAAGDAQGTVKVWQLSTEFTEQGPREAEDLDCLAAEVAA", "length": 536 }, "evidence": [ { "id": "F1NIH1", "url": "https://omabrowser.org/oma/group/F1NIH1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 8, "go_terms": [ { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "F1NIH1", "url": 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Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052555.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015153697", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015153697" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NIL3", "url": "https://www.uniprot.org/uniprotkb/F1NIL3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ATP5L", "url": "https://www.uniprot.org/uniprotkb/F1NIL3", "locus": {} } ], "crossref": [ { "id": "F1NIL3", "url": "https://alphafold.ebi.ac.uk/entry/F1NIL3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000006899", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000006899", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "101749042", "url": 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"header": "tr|A0A8V0ZRM4-1|A0A8V0ZRM4_CHICK Computationally mapped isoform of ATP synthase subunit g OS=Gallus gallus OX=9031 GN=ATP5L PE=1 SV=1 CANONICAL=F1NIL3-1" }, "locus": { "chromosome": "24", "start_pos": 4452577, "end_pos": 4449834, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010059168.1", "url": "https://www.ensembl.org/id/ENSGALT00010059168.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010036110.1", "url": "https://www.ensembl.org/id/ENSGALP00010036110.1" } ] } }, { "isoform_ac": "F1NIL3-1", "url": "https://www.uniprot.org/uniprotkb/F1NIL3/entry#F1NIL3-1", "sequence": { "sequence": "MAQAAQKLVQRLTTRGPQLLSAAVAYSKPRLATFWYYAKVELAPPTPGEIPKAIDSMKAMVRSFQSGRLAQLTVREALRNGLVATEVLMWFYIGEIIGKRGLIGYNV", "length": 107, "header": "tr|F1NIL3-1|F1NIL3_CHICK Isoform 1 of ATP synthase subunit g OS=Gallus gallus OX=9031 GN=ATP5L PE=1 SV=3 CANONICAL=F1NIL3-1" }, "locus": { "chromosome": "24", "start_pos": 4452794, "end_pos": 4449834, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010059172.1", "url": "https://www.ensembl.org/id/ENSGALT00010059172.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010036114.1", "url": "https://www.ensembl.org/id/ENSGALP00010036114.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 46, "start_aa": "Thr", "end_pos": 46, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr46", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:101749042", "name": "", "url": 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], "protein_names": [ { "name": "Carbohydrate sulfotransferase", "type": "recommended", "evidence": [ { "id": "F1NIN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NIN6/entry#names_and_taxonomy" } ] }, { "name": "2.8.2.-", "type": "synonym", "evidence": [ { "id": "F1NIN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NIN6/entry#names_and_taxonomy" } ] }, { "name": "carbohydrate sulfotransferase 9 isoform X4", "type": "synonym", "evidence": [ { "id": "XP_046793434", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046793434" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052533.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_046793434", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046793434" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NIN6", "url": "https://www.uniprot.org/uniprotkb/F1NIN6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CHST9", "url": "https://www.uniprot.org/uniprotkb/F1NIN6", "locus": { "chromosome": "2", "start_pos": 104079549, "end_pos": 104170445, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010005573", "url": "https://www.ensembl.org/id/ENSGALG00010005573" } ] } } ], "crossref": [ { "id": "ENSGALG00000019489", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000019489", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "421089", "url": "https://www.ncbi.nlm.nih.gov/gene/421089", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR005331", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005331", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018011", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018011", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "F1NIN6", "url": "https://www.orthodb.org/?gene=F1NIN6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12137", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12137", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12137:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12137:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03567", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03567", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-2022870", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2022870", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_046793434", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046793434", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1NIN6", "url": "https://www.uniprot.org/uniprotkb/F1NIN6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NIN6-1", "url": "https://www.uniprot.org/uniprotkb/F1NIN6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLPPPETQRKATQSGHIPPGLGRQEVAIMSSRQWQGKADPFGAVAVSLVSGLSDQQKISKPPFSQFKEVYLPPVLHPLNKTLVTGDQWKDVDSIQERRRSFLYEFCKKYNSMKKLRTHLVHIVSRIYVEDRHKVLYCEVPKVGCSNWKRVLMVLNGLATSVRNISHDDVHYGKHLRKLDSYDLKGIYTRLNTYTKAIFVRDPLERLVSAFRDKFEHPNSYYHPVFGKAIIKKYRHNANKEALETGSGVKFKEFIQYLLDSHRPVGMDIHWEQVSKLCYPCLINYDFIGKFETLEEDANYFLQLVGAPAELKFPRFKDRHSSDERTSAEVVRQYLKELSKEERQLTYDFYYLDYLMFNYTSPTV", "length": 363, "header": "tr|F1NIN6-1|F1NIN6_CHICK Isoform 1 of Carbohydrate sulfotransferase OS=Gallus gallus OX=9031 GN=CHST9 PE=3 SV=3 CANONICAL=F1NIN6-1" }, "isoforms": [ { "isoform_ac": "F1NIN6-1", "url": "https://www.uniprot.org/uniprotkb/F1NIN6/entry#F1NIN6-1", "sequence": { "sequence": "MLPPPETQRKATQSGHIPPGLGRQEVAIMSSRQWQGKADPFGAVAVSLVSGLSDQQKISKPPFSQFKEVYLPPVLHPLNKTLVTGDQWKDVDSIQERRRSFLYEFCKKYNSMKKLRTHLVHIVSRIYVEDRHKVLYCEVPKVGCSNWKRVLMVLNGLATSVRNISHDDVHYGKHLRKLDSYDLKGIYTRLNTYTKAIFVRDPLERLVSAFRDKFEHPNSYYHPVFGKAIIKKYRHNANKEALETGSGVKFKEFIQYLLDSHRPVGMDIHWEQVSKLCYPCLINYDFIGKFETLEEDANYFLQLVGAPAELKFPRFKDRHSSDERTSAEVVRQYLKELSKEERQLTYDFYYLDYLMFNYTSPTV", "length": 363, "header": "tr|F1NIN6-1|F1NIN6_CHICK Isoform 1 of Carbohydrate sulfotransferase OS=Gallus gallus OX=9031 GN=CHST9 PE=3 SV=3 CANONICAL=F1NIN6-1" }, "locus": { "chromosome": "2", "start_pos": 104084853, "end_pos": 104083765, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010013360.1", "url": "https://www.ensembl.org/id/ENSGALT00010013360.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010007917.1", "url": "https://www.ensembl.org/id/ENSGALP00010007917.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "R-GGA-2022870", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2022870", "resource": "Reactome", "description": "CS-GAG biosynthesis" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "sulfotransferase activity", "id": "GO:0008146", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008146", "evidence": [ { "database": "UniProtKB", "id": "F1NIN6", "url": "https://www.uniprot.org/uniprotkb/F1NIN6" } ], "pmid": "" }, { "name": "dermatan 4-sulfotransferase activity", "id": "GO:0001537", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001537", "evidence": [ { "database": "UniProtKB", "id": "F1NIN6", "url": "https://www.uniprot.org/uniprotkb/F1NIN6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "carbohydrate biosynthetic process", "id": "GO:0016051", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016051", "evidence": [ { "database": "UniProtKB", "id": "F1NIN6", "url": "https://www.uniprot.org/uniprotkb/F1NIN6" } ], "pmid": "" }, { "name": "sulfur compound metabolic process", "id": "GO:0006790", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006790", "evidence": [ { "database": "UniProtKB", "id": "F1NIN6", "url": "https://www.uniprot.org/uniprotkb/F1NIN6" } ], "pmid": "" }, { "name": "proteoglycan biosynthetic process", "id": "GO:0030166", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030166", "evidence": [ { "database": "UniProtKB", "id": "F1NIN6", "url": "https://www.uniprot.org/uniprotkb/F1NIN6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "F1NIN6", "url": "https://www.uniprot.org/uniprotkb/F1NIN6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 163, "end_pos": 165, "annotation": "n_glycosylation_sequon" }, { "start_pos": 357, "end_pos": 359, "annotation": "n_glycosylation_sequon" }, { "start_pos": 79, "end_pos": 81, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-GGA-1971483", "name": "CHST11,12,13,9 transfer sulfate to (4-)GalNAc", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "Golgi lumen, Golgi membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1NIN6-1", "A0A8V0YCD9-1", "A0A1D5PTT4-1", "A0A8V0ZBF5-1" ], "evidence": [ { "id": "R-GGA-1971483", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1971483" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A1D5PTT4", "gene_name": "CHST13", "activity": [ { "ec_number": "2.8.2.-", "activity": "", "evidence": [ { "id": "A0A1D5PTT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PTT4" } ] } ] }, { "uniprot_ac": "A0A8V0YCD9", "gene_name": "", "activity": [ { "ec_number": "2.8.2.-", "activity": "", "evidence": [ { "id": "A0A8V0YCD9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCD9" } ] } ] }, { "uniprot_ac": "A0A8V0ZBF5", "gene_name": "CHST12", "activity": [ { "ec_number": 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This record is derived from a genomic sequence (NC_052542.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. 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all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000021.1. On Apr 17, 2013 this sequence version replaced XP_416772.3.", "evidence": [ { "database": "RefSeq", "id": "NP_001264657", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264657" } ] }, { "annotation": "Component of the large ribosomal subunit. 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"https://www.ebi.ac.uk/interpro/entry/IPR023672", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:418568", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418568", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "GGRHPCT", "url": "https://omabrowser.org/oma/group/GGRHPCT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1NIX0", "url": "https://www.orthodb.org/?gene=F1NIX0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13691", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13691", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13691:SF16", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13691:SF16", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "pdb_00008q7z", "url": "https://www.rcsb.org/structure/pdb_00008q7z", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00008q87", "url": "https://www.rcsb.org/structure/pdb_00008q87", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "8Q7Z", "url": "https://www.rcsb.org/structure/8Q7Z", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "8Q87", "url": "https://www.rcsb.org/structure/8Q87", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "PF00181", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00181", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF03947", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03947", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-1799339", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1799339", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-72706", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-72706", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9629569", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9629569", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-975956", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-975956", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-975957", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-975957", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9954709", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9954709", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9954714", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9954714", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9954716", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9954716", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001264657", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264657", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1NIX0", "url": "https://www.uniprot.org/uniprotkb/F1NIX0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NIX0-1", "url": "https://www.uniprot.org/uniprotkb/F1NIX0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGRVIRGQRKGAGSVFRAHVKHRKGPAKLRAVDFAERHGYIKGIVKDIIHDPGRGAPLAKIAFRDPYRFKKRTELFIAAEGIHTGQFVYCGKKAQLNIGNVLPVGTMPEGTIVCCLEEKPGDRGKLARASGNYATVISHNPETKKTRVKLPSGSKKVISSANRAVVGIVAGGGRIDKPILKAGRAYHKYKAKRNCWPRVRGVAMNPVEHPFGGGNHQHIGKPSTIRRDAPAGRKVGLIAARRTGRLRGTKTVQEKEN", "length": 257, "header": "tr|F1NIX0-1|F1NIX0_CHICK Isoform 1 of Large ribosomal subunit protein uL2 OS=Gallus gallus OX=9031 GN=RPL8 PE=1 SV=2 CANONICAL=F1NIX0-1" }, "isoforms": [ { "isoform_ac": "F1NIX0-1", "url": "https://www.uniprot.org/uniprotkb/F1NIX0/entry#F1NIX0-1", "sequence": { "sequence": "MGRVIRGQRKGAGSVFRAHVKHRKGPAKLRAVDFAERHGYIKGIVKDIIHDPGRGAPLAKIAFRDPYRFKKRTELFIAAEGIHTGQFVYCGKKAQLNIGNVLPVGTMPEGTIVCCLEEKPGDRGKLARASGNYATVISHNPETKKTRVKLPSGSKKVISSANRAVVGIVAGGGRIDKPILKAGRAYHKYKAKRNCWPRVRGVAMNPVEHPFGGGNHQHIGKPSTIRRDAPAGRKVGLIAARRTGRLRGTKTVQEKEN", "length": 257, "header": "tr|F1NIX0-1|F1NIX0_CHICK Isoform 1 of Large ribosomal subunit protein uL2 OS=Gallus gallus OX=9031 GN=RPL8 PE=1 SV=2 CANONICAL=F1NIX0-1" }, "locus": { "chromosome": "1", "start_pos": 112167536, "end_pos": 112164127, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010005743.1", "url": "https://www.ensembl.org/id/ENSGALT00010005743.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010003571.1", "url": "https://www.ensembl.org/id/ENSGALP00010003571.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Cryo-EM structure of the inactive ribosome complex accumulated in chick embryo cells in cold-stress conditions.", "journal": "FEBS Lett.", "date": "2024", "authors": "Nurullina Liliia, Terrosu Salvatore, Myasnikov Alexander G, Jenner Lasse Bohl, Yusupov Marat", "evidence": [ { "database": "UniProtKB", "id": "F1NIX0", "url": "https://www.uniprot.org/uniprotkb/F1NIX0" } ], "reference": [ { "type": "PubMed", "id": "38395592", "url": "https://glygen.org/publication/PubMed/38395592" } ] } ], "pathway": [ { "id": "gga:418568", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418568", "resource": "KEGG Pathway" }, { "id": "R-GGA-1799339", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1799339", "resource": "Reactome", "description": "SRP-dependent cotranslational protein targeting to membrane" }, { "id": "R-GGA-72706", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-72706", "resource": "Reactome", "description": "GTP hydrolysis and joining of the 60S ribosomal subunit" }, { "id": "R-GGA-9629569", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9629569", "resource": "Reactome", "description": "Protein hydroxylation" }, { "id": "R-GGA-975956", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-975956", "resource": "Reactome", "description": "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" }, { "id": "R-GGA-975957", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-975957", "resource": "Reactome", "description": "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" }, { "id": "R-GGA-9954709", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9954709", "resource": "Reactome", "description": "Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide" }, { "id": "R-GGA-9954714", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9954714", "resource": "Reactome", "description": "PELO:HBS1L and ABCE1 dissociate a ribosome on a non-stop mRNA" }, { "id": "R-GGA-9954716", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9954716", "resource": "Reactome", "description": "ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA" } ], "orthologs": [ { "uniprot_canonical_ac": "F2Z567-1", "protein_name": "Large ribosomal subunit protein uL2", "gene_name": "RPL8", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGRVIRGQRKGAGSVFRAHVKHRKGAARLRAVDFAERHGYIKGIVKDIIHDPGRGAPLAKVVFRDPYRFKKRTELFIAAEGIHTGQFVYCGKKAQLNIGNVLPVGTMPEGTIVCCLEEKPGDRGKLARASGNYATVISHNPETKKTRVKLPSGSKKVISSANRAVVGVVAGGGRIDKPILKAGRAYHKYKAKRNCWPRVRGVAMNPVEHPFGGGNHQHIGKPSTIRRDAPAGRKVGLIAARRTGRLRGTKTVQEKEN", "length": 257 }, "evidence": [ { "id": "F1NIX0", "url": "https://omabrowser.org/oma/group/F1NIX0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P13023-1", "protein_name": "Large ribosomal subunit protein uL2", "gene_name": "rpl8", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MGRIIRAQRKGKAGSVFGAHTHHRKGTPRFRALDYAERQGYVKGVVKEIIHDPGRGAPLARVVFKGLTQFKLDKQLFIAPEGMHTGQFVFAGKKATLTIGNILPIGKLPEGTIICNVEEKLGDCGAVARCSGNYATIVSHNPDEGVTRIKLPSGSKKNVSSLARAMIGIVAGGGRIDKPMLKAGRAFHKYRVKKNNWPKVRGVAMNPVEHPHGGGNHQHVGHATTTKRDDPAGKKVGLIAARRTGRLRGTKNISE", "length": 255 }, "evidence": [ { "id": "F1NIX0", "url": "https://omabrowser.org/oma/group/F1NIX0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "P62917-1", "protein_name": "Large ribosomal subunit protein uL2", "gene_name": "RPL8", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGRVIRGQRKGAGSVFRAHVKHRKGAARLRAVDFAERHGYIKGIVKDIIHDPGRGAPLAKVVFRDPYRFKKRTELFIAAEGIHTGQFVYCGKKAQLNIGNVLPVGTMPEGTIVCCLEEKPGDRGKLARASGNYATVISHNPETKKTRVKLPSGSKKVISSANRAVVGVVAGGGRIDKPILKAGRAYHKYKAKRNCWPRVRGVAMNPVEHPFGGGNHQHIGKPSTIRRDAPAGRKVGLIAARRTGRLRGTKTVQEKEN", "length": 257 }, 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"MGRVIRGQRKGAGSVFRAHVKHRKGAARLRAVDFAERHGYIKGIVKDIIHDPGRGAPLAKVVFRDPYRFKKRTELFIAAEGIHTGQFVYCGKKAQLNIGNVLPVGTMPEGTIVCCLEEKPGDRGKLARASGNYATVISHNPETKKTRVKLPSGSKKVISSANRAVVGVVAGGGRIDKPILKAGRAYHKYKAKRNCWPRVRGVAMNPVEHPFGGGNHQHIGKPSTIRRDAPAGRKVGLIAARRTGRLRGTKTVQEKEN", "length": 257 }, "evidence": [ { "id": "F1NIX0", "url": "https://omabrowser.org/oma/group/F1NIX0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q42064-1", "protein_name": "Large ribosomal subunit protein uL2x", "gene_name": "RPL8C", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MGRVIRAQRKGAGSVFKSHTHHRKGPAKFRSLDFGERNGYLKGVVTEIIHDPGRGAPLARVAFRHPFRFKKQKELFVAAEGMYTGQFLYCGKKATLVVGNVLPLRSIPEGAVICNVEHHVGDRGVFARASGDYAIVIAHNPDNDTSRIKLPSGSKKIVPSGCRAMIGQVAGGGRTEKPMLKAGNAYHKYRVKRNCWPKVRGVAMNPVEHPHGGGNHQHIGHASTVRRDAPPGKKVGLIAARRTGRLRGQAAALASKAD", "length": 258 }, "evidence": [ { "id": "F1NIX0", "url": "https://omabrowser.org/oma/group/F1NIX0/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q6P0V6-1", "protein_name": "Large ribosomal subunit protein uL2", "gene_name": "rpl8", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MGRVIRGQRKGAGSVFKAHVKHRKGAAKLRHIDFAERHGYIKGIVKDIIHDPGRGAPLAKVMFRDPYRFKKRTELFIAAEGIHTGQFIYCGKKAQLNIGNVLPVGTMPEGTIVCCLEEKPGDRGKLARASGNYATVISHNPETKKSRVKLPSGSKKVISSANRAVVGVVAGGGRIDKPILKAGRAYHKYKAKRNCWPRVRGVAMNPVEHPFGGGNHQHIGKPSTIRRDAPAGRKVGLIAARRTGRLRGTKTVQDKEN", "length": 257 }, "evidence": [ { "id": "F1NIX0", "url": "https://omabrowser.org/oma/group/F1NIX0/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q9V3G1-1", "protein_name": "Large ribosomal subunit protein uL2", "gene_name": "RpL8", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": 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"name": "rRNA binding", "id": "GO:0019843", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019843", "evidence": [ { "database": "UniProtKB", "id": "F1NIX0", "url": "https://www.uniprot.org/uniprotkb/F1NIX0" } ], "pmid": "" }, { "name": "structural constituent of ribosome", "id": "GO:0003735", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003735", "evidence": [ { "database": "UniProtKB", "id": "F1NIX0", "url": "https://www.uniprot.org/uniprotkb/F1NIX0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "F1NIX0", "url": "https://www.uniprot.org/uniprotkb/F1NIX0" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "F1NIX0", "url": "https://www.uniprot.org/uniprotkb/F1NIX0" } ], "pmid": "" }, { "name": "postsynaptic density", "id": "GO:0014069", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0014069", "evidence": [ { "database": "UniProtKB", "id": "F1NIX0", "url": "https://www.uniprot.org/uniprotkb/F1NIX0" } ], "pmid": "" }, { "name": "cytosolic large ribosomal subunit", "id": "GO:0022625", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022625", "evidence": [ { "database": "UniProtKB", "id": "F1NIX0", "url": "https://www.uniprot.org/uniprotkb/F1NIX0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "cytoplasmic translation", "id": "GO:0002181", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002181", "evidence": [ { "database": "UniProtKB", "id": "F1NIX0", "url": "https://www.uniprot.org/uniprotkb/F1NIX0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1NIX0-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 257, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1NIX0-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1NIX0" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1NIX0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NIX0" }, { "id": "SM01382", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM01382" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Large ribosomal subunit protein uL2 C-terminal", "eco_id": "ECO_0000259", "start_pos": 96, "end_pos": 231, "start_aa": "Leu", "end_aa": "Ala", "glycosite_overlap": "" }, { "evidence": [ { "id": "F1NIX0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NIX0" }, { "id": "SM01383", "database": "SMART", "url": 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"https://www.rcsb.org/structure/8Q7Z" } ], "binding_site_uniprot": 217, "amino_acid": "Gln", "chebi_lig_id": "CHEBI_18420", "ligand": "Mg(2+)", "ligand_label": "5", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0007829", "start_pos": 217, "end_pos": 217, "start_aa": "Gln", "end_aa": "Gln", "glycosite_overlap": "" }, { "evidence": [ { "id": "F1NIX0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NIX0#function" }, { "id": "F1NIX0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NIX0" }, { "id": "8Q7Z", "database": "PDB", "url": "https://www.rcsb.org/structure/8Q7Z" }, { "id": "8Q87", "database": "PDB", "url": "https://www.rcsb.org/structure/8Q87" } ], "binding_site_uniprot": 218, "amino_acid": "His", "chebi_lig_id": "CHEBI_18420", "ligand": "Mg(2+)", "ligand_label": "3", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0007829", "start_pos": 218, "end_pos": 218, "start_aa": "His", "end_aa": "His", "glycosite_overlap": "" } ], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 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"table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "F1NJ17-1", "uniprot_ac": "F1NJ17", "uniprot_id": "F1NJ17_CHICK", "mass": { "chemical_mass": 38976.0, "monoisotopic_mass": 38976.0 }, "refseq": { "ac": "NP_996867", "name": "gap junction alpha-4 protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_996867" }, "gene_names": [ { "name": "GJA4", "type": "recommended", "evidence": [ { "id": "F1NJ17", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NJ17" } ] }, { "name": "Cx39", "type": "synonym", "evidence": [ { "id": "NP_996867", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_996867" } ] }, { "name": "GJA4", "type": "synonym", "evidence": [ { "id": "NP_996867", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_996867" } ] }, { "name": "ggCx39", "type": "synonym", "evidence": [ { "id": "NP_996867", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_996867" } ] } ], "protein_names": [ { "name": "Gap junction protein", "type": "recommended", "evidence": [ { "id": "F1NJ17", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NJ17/entry#names_and_taxonomy" } ] }, { "name": "connexin 37", "type": "synonym", "evidence": [ { "id": "NP_996867", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_996867" } ] }, { "name": "connexin 39", "type": "synonym", "evidence": [ { "id": "NP_996867", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_996867" } ] }, { "name": "gap junction alpha-4 protein", "type": "synonym", "evidence": [ { "id": "NP_996867", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_996867" } ] } ], "function": [ { "annotation": "One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.", "evidence": [ { "database": "UniProtKB", "id": "F1NJ17", "url": "https://www.uniprot.org/uniprotkb/F1NJ17#function" }, { "database": "UniProtKB", "id": "ARBA00003922", "url": "https://www.uniprot.org/uniprotkb/ARBA00003922#function" }, { "database": "UniProtKB", "id": "RU000630", "url": "https://www.uniprot.org/uniprotkb/RU000630#function" } ] }, { "annotation": "VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000339.1. On Jan 23, 2007 this sequence version replaced NP_996867.2.", "evidence": [ { "database": "RefSeq", "id": "NP_996867", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_996867" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NJ17", "url": "https://www.uniprot.org/uniprotkb/F1NJ17" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "GJA4", "url": "https://www.uniprot.org/uniprotkb/F1NJ17", "locus": { "chromosome": "23", "start_pos": 4805835, "end_pos": 4813435, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010016953", "url": "https://www.ensembl.org/id/ENSGALG00010016953" } ] } } ], "crossref": [ { "id": "ENSGALG00000002532", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000002532", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "404529", "url": "https://www.ncbi.nlm.nih.gov/gene/404529", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000500", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000500", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013092", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013092", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017990", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017990", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019570", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019570", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034634", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034634", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038359", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038359", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:404529", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:404529", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MWTYIIS", "url": "https://omabrowser.org/oma/group/MWTYIIS/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1NJ17", "url": "https://www.orthodb.org/?gene=F1NJ17", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11984", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11984", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11984:SF54", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11984:SF54", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00029", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00029", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-190861", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-190861", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_996867", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_996867", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1NJ17", "url": "https://www.uniprot.org/uniprotkb/F1NJ17", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NJ17-1", "url": "https://www.uniprot.org/uniprotkb/F1NJ17-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGDWGFLEKLLDQVQEHSTVIGKIWLTVLFIFRILILGLAGESVWGDEQSDFVCNTKQPGCTNVCYDKAFPISHIRYWVLQFLFVSTPTLIYLGHVVYLSRKEEKLKQQENELRAIHSKDPKIEQALAAVEKKMSKIYVTEDGRLKIRGALMWTYVISVICKSIFEAGFLVGQWYLYGFSMVPRYVCRRDPCPHQVDCFISRPTEKTIFIIFMMVMGLISLILNLLELFHLCCKSLLSSIKKVPVPVGPSQSAFADDMGSGPYPAKHYPFLPMAESHTPPYQAYNKLSSEQNWANFRNEENLALGSGTRPLSDPYAPRAPDAPIPEEKQCSRPSSSASKKQYV", "length": 343, "header": "tr|F1NJ17-1|F1NJ17_CHICK Isoform 1 of Gap junction protein OS=Gallus gallus OX=9031 GN=GJA4 PE=3 SV=1 CANONICAL=F1NJ17-1" }, "isoforms": [ { "isoform_ac": "F1NJ17-1", "url": "https://www.uniprot.org/uniprotkb/F1NJ17/entry#F1NJ17-1", "sequence": { "sequence": "MGDWGFLEKLLDQVQEHSTVIGKIWLTVLFIFRILILGLAGESVWGDEQSDFVCNTKQPGCTNVCYDKAFPISHIRYWVLQFLFVSTPTLIYLGHVVYLSRKEEKLKQQENELRAIHSKDPKIEQALAAVEKKMSKIYVTEDGRLKIRGALMWTYVISVICKSIFEAGFLVGQWYLYGFSMVPRYVCRRDPCPHQVDCFISRPTEKTIFIIFMMVMGLISLILNLLELFHLCCKSLLSSIKKVPVPVGPSQSAFADDMGSGPYPAKHYPFLPMAESHTPPYQAYNKLSSEQNWANFRNEENLALGSGTRPLSDPYAPRAPDAPIPEEKQCSRPSSSASKKQYV", "length": 343, "header": "tr|F1NJ17-1|F1NJ17_CHICK Isoform 1 of Gap junction protein OS=Gallus gallus OX=9031 GN=GJA4 PE=3 SV=1 CANONICAL=F1NJ17-1" }, "locus": { "chromosome": "23", "start_pos": 4810067, "end_pos": 4809039, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010040932.1", "url": "https://www.ensembl.org/id/ENSGALT00010040932.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023896.1", "url": "https://www.ensembl.org/id/ENSGALP00010023896.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:404529", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:404529", "resource": "KEGG Pathway" }, { "id": "R-GGA-190861", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-190861", "resource": "Reactome", "description": "Gap junction assembly" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287AVB1-1", "protein_name": "Gap junction protein", "gene_name": "GJA4", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGDWGFLEKLLDQVQEHSTVVGKIWLTVLFIFRILILGLAGESVWGDEQSDFECNTAQPGCTNVCYDQAFPISHIRYWVLQFLFVSTPTLVYLGHVIYLSRREERLRQKEGELRALPAKDPRVERALAAIERQMAKISVAEDGHLRIRGALMGTYVASVLCKSVLEAGFLYGQWRLYGWTMEPVFVCQRSPCPYLVDCFVSRPTEKTIFIIFMLVVGLISLVLNLLELAYLLCRCLSRGIRARRDQDTPPAQGTSSEPYADQVFFYLPMGEGPSSPPCPTYNGLSSSEQNWANLTTEERLASSRPPLFLDPPPQSGRKPPSRPSSSASKKQYV", "length": 333 }, "evidence": [ { "id": "F1NJ17", "url": "https://omabrowser.org/oma/group/F1NJ17/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A4IFL1-1", "protein_name": "Gap junction alpha-4 protein", "gene_name": "GJA4", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGDWGFLEKLLDQVQEHSTVVGKIWLTVLFIFRILILGLAGESVWGDEQSDFECNTAQPGCTNVCYDQAFPISHIRYWVLQFLFVSTPTLVYLGHVIYLSRREERLRQKEGELRALPAKDPRVERALASIERQMAKISVAEDGHLRIRGALMGTYVASVLCKSVLEAGFLYGQWRLYGWTMEPVFVCQRSPCPYLVDCFVSRPTEKTIFIIFMLVVGLISLVLNLLELAYLLCRCLSRGVRARQRQDAPPAPGTSSEPYADQVFFYLPMSEGPSSPPCPTYNGLSSSEQNWANLTTEERLASSRAPLFLDPPPQTGRKSPSRPSSSASKKQYV", "length": 333 }, "evidence": [ { "id": "F1NJ17", "url": "https://omabrowser.org/oma/group/F1NJ17/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P28235-1", "protein_name": "Gap junction alpha-4 protein", "gene_name": "Gja4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGDWGFLEKLLDQVQEHSTVVGKIWLTVLFIFRILILGLAGESVWGDEQSDFECNTAQPGCTNVCYDQAFPISHIRYWVLQFLFVSTPTLIYLGHVIYLSRREERLRQKEGELRALPSKDLHVERALAAIEHQMAKISVAEDGRLRIRGALMGTYVVSVLCKSVLEAGFLYGQWRLYGWTMEPVFVCQRAPCPHIVDCYVSRPTEKTIFIIFMLVVGVISLVLNLLELVHLLCRCVSREIKARRDHDARPAQGSASDPYPEQVFFYLPMGEGPSSPPCPTYNGLSSTEQNWANLTTEERLTSSRPPPFVNTAPQGGRKSPSRPNSSASKKQYV", "length": 333 }, "evidence": [ { "id": "F1NJ17", "url": "https://omabrowser.org/oma/group/F1NJ17/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P35212-1", "protein_name": "Gap junction alpha-4 protein", "gene_name": "GJA4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGDWGFLEKLLDQVQEHSTVVGKIWLTVLFIFRILILGLAGESVWGDEQSDFECNTAQPGCTNVCYDQAFPISHIRYWVLQFLFVSTPTLVYLGHVIYLSRREERLRQKEGELRALPAKDPQVERALAAVERQMAKISVAEDGRLRIRGALMGTYVASVLCKSVLEAGFLYGQWRLYGWTMEPVFVCQRAPCPYLVDCFVSRPTEKTIFIIFMLVVGLISLVLNLLELVHLLCRCLSRGMRARQGQDAPPTQGTSSDPYTDQVFFYLPVGQGPSSPPCPTYNGLSSSEQNWANLTTEERLASSRPPLFLDPPPQNGQKPPSRPSSSASKKQYV", "length": 333 }, "evidence": [ { "id": "F1NJ17", "url": "https://omabrowser.org/oma/group/F1NJ17/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q03190-1", "protein_name": "Gap junction alpha-4 protein", "gene_name": "Gja4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGDWGFLEKLLDQVQEHSTVVGKIWLTVLFIFRILILGLAGESVWGDEQSDFECNTAQPGCTNVCYDQAFPISHIRYWVLQFLFVSTPTLIYLGHVIYLSRREERLRQKEGELRALPSKDPHVERALAAIEHQMAKISVAEDGRLRIRGALMGTYVISVLCKSVLEAGFLYGQWRLYGWTMEPVFVCQRAPCPHVVDCYVSRPTEKTIFIIFMLVVGVISLVLNLLELVHLLCRCVSREIKARRDHDTRPAQGSASDPYPEQVFFYLPMGEGPSSPPCPTYNGLSSTEQNWANLTTEERLTSTRPPPFVNAAPQGGQKSSSRPNSSASKKQYV", "length": 333 }, "evidence": [ { "id": "F1NJ17", "url": "https://omabrowser.org/oma/group/F1NJ17/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "cell-cell signaling", "id": "GO:0007267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007267", "evidence": [ { "database": "UniProtKB", "id": "F1NJ17", "url": "https://www.uniprot.org/uniprotkb/F1NJ17" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "connexin complex", "id": "GO:0005922", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005922", "evidence": [ { "database": "UniProtKB", "id": "F1NJ17", "url": "https://www.uniprot.org/uniprotkb/F1NJ17" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "gap junction channel activity", "id": "GO:0005243", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005243", "evidence": [ { "database": "UniProtKB", "id": "F1NJ17", "url": "https://www.uniprot.org/uniprotkb/F1NJ17" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1NJ17", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NJ17" }, { "id": "SM00037", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00037" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Connexin N-terminal", "eco_id": "ECO_0000259", "start_pos": 43, "end_pos": 76, "start_aa": "Ser", "end_aa": "Arg", "glycosite_overlap": "" }, { "evidence": [ { "id": "F1NJ17", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NJ17" }, { "id": "SM01089", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM01089" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Connexin cysteine-rich", "eco_id": "ECO_0000259", "start_pos": 165, "end_pos": 231, "start_aa": "Phe", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1NJ18-1", "uniprot_ac": "F1NJ18", "uniprot_id": "F1NJ18_CHICK", "mass": { "chemical_mass": 66231.0, "monoisotopic_mass": 66231.0 }, "refseq": { "ac": "XP_419256", "name": "G-protein coupled receptor 37-like 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_419256" }, "gene_names": [ { "name": "GPR37L1", "type": "recommended", "evidence": [ { "id": "F1NJ18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NJ18" } ] }, { "name": "GPR37L1", "type": "synonym", "evidence": [ { "id": "XP_419256", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_419256" } ] } ], "protein_names": [ { "name": "G protein-coupled receptor 37 like 1", "type": "synonym", "evidence": [ { "id": "F1NJ18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NJ18/entry#names_and_taxonomy" } ] }, { "name": "G-protein coupled receptor 37-like 1", "type": "synonym", "evidence": [ { "id": "XP_419256", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_419256" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052557.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 19, 2013 this sequence version replaced XP_419256.3. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_419256", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_419256" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NJ18", "url": "https://www.uniprot.org/uniprotkb/F1NJ18" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "GPR37L1", "url": "https://www.uniprot.org/uniprotkb/F1NJ18", "locus": { "chromosome": "26", "start_pos": 390066, "end_pos": 385742, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010024486", "url": "https://www.ensembl.org/id/ENSGALG00010024486" } ] } } ], "crossref": [ { "id": "F1NJ18", "url": "https://alphafold.ebi.ac.uk/entry/F1NJ18", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000000607", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000000607", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd15126", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15126", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "421176", "url": "https://www.ncbi.nlm.nih.gov/gene/421176", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003909", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003909", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:421176", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:421176", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DSCVMKP", "url": "https://omabrowser.org/oma/group/DSCVMKP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1NJ18", "url": "https://www.orthodb.org/?gene=F1NJ18", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46216", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46216", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46216:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46216:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00001", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00001", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-375276", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-375276", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-418594", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-418594", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_419256", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_419256", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1NJ18", "url": "https://www.uniprot.org/uniprotkb/F1NJ18", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NJ18-1", "url": "https://www.uniprot.org/uniprotkb/F1NJ18-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVGLEGPWKVTNPCLGLVALHQFRLPRVPWGDAGRCRRAVGDAQPGLWLSALGSVPAAVGDQQRARLCRSFILPGVLRSAHSSGRSRTERSSPGPSSFPAAPGLLRQTLPAEGAEDIMPSPPSLVLLLLALPGAAAMPGAAVQHAEGGVHPNRGAGGGGMLPVAAQDNVELKARPRRGTVEDSKSVQQYVPGVRVEFPRPINAASLHPTRAMVPSSTDPSEQQRGVPTDGGAEPATNLTTVSDKRLQIQNPLYPVTENSYSAYAVMFLSLIVFVVGIIGNLSVMCIVWHNYYMKSAWNSILASLAFWDFLILFFCLPVVIFNEITKKRLLGDISCRIVPFMEVSSLGVTTFSLCALGIDRFHAATSPQASARPIEQCQSIIAKLAVIWVGSMTLSVPEVLLWQLAQDTSPVSGVVTEYCTMKPSSNLPESVYSLVLTYQNARMWWYFGCYFCLPILFTVSCQLVTRRIRGTEKKAECRGTKHSQCESHLNCTIIGLTIIYGLCTTPENVCNIVVAYMSPDMSKQTLDLLNLINQFFLFFKCSVTPVLLLCLCRPLGQAFMDCCCCCCEGCGPDAASSEGSADSKLKTEMSSSIFFDKPRESPPPLLALGTPC", "length": 612, "header": "tr|F1NJ18-1|F1NJ18_CHICK Isoform 1 of G protein-coupled receptor 37 like 1 OS=Gallus gallus OX=9031 GN=GPR37L1 PE=4 SV=3 CANONICAL=F1NJ18-1" }, "isoforms": [ { "isoform_ac": "F1NJ18-1", "url": "https://www.uniprot.org/uniprotkb/F1NJ18/entry#F1NJ18-1", "sequence": { "sequence": "MVGLEGPWKVTNPCLGLVALHQFRLPRVPWGDAGRCRRAVGDAQPGLWLSALGSVPAAVGDQQRARLCRSFILPGVLRSAHSSGRSRTERSSPGPSSFPAAPGLLRQTLPAEGAEDIMPSPPSLVLLLLALPGAAAMPGAAVQHAEGGVHPNRGAGGGGMLPVAAQDNVELKARPRRGTVEDSKSVQQYVPGVRVEFPRPINAASLHPTRAMVPSSTDPSEQQRGVPTDGGAEPATNLTTVSDKRLQIQNPLYPVTENSYSAYAVMFLSLIVFVVGIIGNLSVMCIVWHNYYMKSAWNSILASLAFWDFLILFFCLPVVIFNEITKKRLLGDISCRIVPFMEVSSLGVTTFSLCALGIDRFHAATSPQASARPIEQCQSIIAKLAVIWVGSMTLSVPEVLLWQLAQDTSPVSGVVTEYCTMKPSSNLPESVYSLVLTYQNARMWWYFGCYFCLPILFTVSCQLVTRRIRGTEKKAECRGTKHSQCESHLNCTIIGLTIIYGLCTTPENVCNIVVAYMSPDMSKQTLDLLNLINQFFLFFKCSVTPVLLLCLCRPLGQAFMDCCCCCCEGCGPDAASSEGSADSKLKTEMSSSIFFDKPRESPPPLLALGTPC", "length": 612, "header": "tr|F1NJ18-1|F1NJ18_CHICK Isoform 1 of G protein-coupled receptor 37 like 1 OS=Gallus gallus OX=9031 GN=GPR37L1 PE=4 SV=3 CANONICAL=F1NJ18-1" }, "locus": { "chromosome": "26", "start_pos": 389633, "end_pos": 385941, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010059721.1", "url": "https://www.ensembl.org/id/ENSGALT00010059721.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010036484.1", "url": "https://www.ensembl.org/id/ENSGALP00010036484.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:421176", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:421176", "resource": "KEGG Pathway" }, { "id": "R-GGA-375276", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-375276", "resource": "Reactome", "description": "Peptide ligand-binding receptors" }, { "id": "R-GGA-418594", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-418594", "resource": "Reactome", "description": "G alpha (i) signalling events" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A286ZX16-1", "protein_name": "G protein-coupled receptor 37 like 1", "gene_name": "GPR37L1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRWLWPLVVSLAVASAVGPRRIPGGAALQRGRSVRGTEEEEEGAKGVQQYVPEEWPEYPRPIHPAGPQPTEPGVATSPHPDGAVRAGGNATGTPGRPLQMQNPLYPVTESSYGAYAVLLLALVLFAVGIVGNLSVMCIVWHSYHLKSAWNSILASLALWDFLVLFFCLPVVVFHEITKQRLLGDASCRAVPFVEVSSLGVTTFSLCALGIDRFHVATSTLPKARPIEPCPSILAKLAVIWVGSMTLAVPELLLWQLVQEPSPTVGTVDTCAMKPSARLPESLYSLVMTYQNARMWWSFGCYFCLPILFTVTCQLVTWRVRGPPGRKPECRPGKHEQCEGQLSSTVVGLTAVYALCTLPENVCNVVAAYLSATLARQTLDLLGLVTQFSTFLKAAVTPVLLLCVCRPLGRAFLDCCCCCCEGCGGAAAGGVDGKLKTEMAASAYFHKPREAPLLALGTPC", "length": 459 }, "evidence": [ { "id": "F1NJ18", "url": "https://omabrowser.org/oma/group/F1NJ18/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3H3H7-1", "protein_name": "G-protein coupled receptor 37-like 1", "gene_name": "Gpr37l1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MRWLWPLAFSLAVVLAVGLSGGSGAATSTLGGHRAKVQEQRSRLRRGTKDEGPKEVQHYVPDEWAEYPRPIHPAGLQPTKTLVATSPSPDKDGATPDSGQELRTNLTGTPSQRLQIQNPLYPVTESSYSAYAVMLLALVVFAVGIVGNLSVMCIVWHSYYLKSAWNSILASLALWDFLVLFFCLPIVIFNEITKQRLLGDVSCRAVPFMEVSSLGVTTFSLCALGIDRFHVATSTLPKVRPIERCQSILAKLAVIWVGSMMLAVPELLLWQLAQEPAPTMGTVDSCIMKPSANLPESVYSLVMTYQNARMWWYFGCYFCLPILFTVTCQLVTWRVRGPPGRKPECRAGKHEQCESQLNSTVVGLTVVYAFCTLPENVCNIVVAYLSTELTRQTLDLLGLVNQFSTFFKGAITPVLLLCICRPLGQAFLDCCCCCCCEECGGASDSSATAGVGSKLKTEVSSSIYFHKPRESPPLLPLGTPC", "length": 481 }, "evidence": [ { "id": "F1NJ18", "url": "https://omabrowser.org/oma/group/F1NJ18/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "O60883-1", "protein_name": "G protein-coupled receptor 37-like 1", "gene_name": "GPR37L1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRWLWPLAVSLAVILAVGLSRVSGGAPLHLGRHRAETQEQQSRSKRGTEDEEAKGVQQYVPEEWAEYPRPIHPAGLQPTKPLVATSPNPGKDGGTPDSGQELRGNLTGAPGQRLQIQNPLYPVTESSYSAYAIMLLALVVFAVGIVGNLSVMCIVWHSYYLKSAWNSILASLALWDFLVLFFCLPIVIFNEITKQRLLGDVSCRAVPFMEVSSLGVTTFSLCALGIDRFHVATSTLPKVRPIERCQSILAKLAVIWVGSMTLAVPELLLWQLAQEPAPTMGTLDSCIMKPSASLPESLYSLVMTYQNARMWWYFGCYFCLPILFTVTCQLVTWRVRGPPGRKSECRASKHEQCESQLNSTVVGLTVVYAFCTLPENVCNIVVAYLSTELTRQTLDLLGLINQFSTFFKGAITPVLLLCICRPLGQAFLDCCCCCCCEECGGASEASAANGSDNKLKTEVSSSIYFHKPRESPPLLPLGTPC", "length": 481 }, "evidence": [ { "id": "F1NJ18", "url": "https://omabrowser.org/oma/group/F1NJ18/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q17QD8-1", "protein_name": "G protein-coupled receptor 37-like 1", "gene_name": "GPR37L1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MRWLWPLGVSLAVALAAGPERAPRGVWLQQGGHQPVAQEQPDRSRRGAEREDAKGLQQYVPEGWAEYPRPIRPAALQPTQPWVAASPSPDRARATGGSGQEPQGNVTGPPGQRPQVQNPLYPVTERSYGAYAVLLLALLLFAVGIVGSLAVMCIVWHSYYLKSAWNSVLASLALWDFLVLFFCLPVVTFHEITKQRLLGAVSCRAVPFVEVSSLGVTTFSLCALGIDRFHVATSTLPKARPIEPCPSILAKLAVIWVGSMTLAAPELLLWQLVREPSPAAGTVDTCIMKPSAHLPESLYSLVLTYQNARMWWSFGCYFCLPVLFTVTCQLVTWRVRGTPGRKPESRPGPQEPRGARPSSTVAGLAAVHALCALPENVCNVVAAYLSAALTRQTLELLGLVTQFSTFFKAALTPLLLLCVSRPLGRAFLDCCCCCCGEGCGEGCGGRAAPAGPRAKLHTELSASGYFHKPREAPPLLALGTPC", "length": 482 }, "evidence": [ { "id": "F1NJ18", "url": "https://omabrowser.org/oma/group/F1NJ18/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q99JG2-1", "protein_name": "G protein-coupled receptor 37-like 1", "gene_name": "Gpr37l1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": 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"table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1NJ53-1", "uniprot_ac": "F1NJ53", "uniprot_id": "F1NJ53_CHICK", "mass": { "chemical_mass": 9653.0, "monoisotopic_mass": 9653.0 }, "refseq": { "ac": "NP_001289119", "name": "small muscular protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001289119" }, "gene_names": [ { "name": "SMPX", "type": "recommended", "evidence": [ { "id": "F1NJ53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NJ53" } ] }, { "name": "SMPX", "type": "synonym", "evidence": [ { "id": "NP_001289119", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001289119" } ] } ], "protein_names": [ { "name": "Small muscular protein", "type": "recommended", "evidence": [ { "id": "F1NJ53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NJ53/entry#names_and_taxonomy" } ] }, { "name": "small muscle protein, X-linked", "type": "synonym", "evidence": [ { "id": "NP_001289119", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001289119" } ] }, { "name": "small muscular protein", "type": "synonym", "evidence": [ { "id": "NP_001289119", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001289119" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: SRR13267649.140521.1, SRR13267656.9001.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992323, SAMEA103992393 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000021.1. On Oct 4, 2014 this sequence version replaced XP_003640562.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001289119", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001289119" } ] }, { "annotation": "Plays a role in the regulatory network through which muscle cells coordinate their structural and functional states during growth, adaptation, and repair.", "evidence": [ { "database": "UniProtKB", "id": "F1NJ53", "url": "https://www.uniprot.org/uniprotkb/F1NJ53#function" }, { "database": "UniProtKB", "id": "ARBA00002671", "url": "https://www.uniprot.org/uniprotkb/ARBA00002671#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NJ53", "url": "https://www.uniprot.org/uniprotkb/F1NJ53" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SMPX", 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"id": "PPRKKEC", "url": "https://omabrowser.org/oma/group/PPRKKEC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1NJ53", "url": "https://www.orthodb.org/?gene=F1NJ53", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR17416", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR17416", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR17416:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR17416:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15355", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15355", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001289119", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001289119", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1NJ53", "url": "https://www.uniprot.org/uniprotkb/F1NJ53", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NJ53-1", "url": "https://www.uniprot.org/uniprotkb/F1NJ53-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSKQPASHVKAIQANINIPMGAFRPGAGHPHKRKEVTPEEVEESVPATEEEKDKKHLPGARKLPGPAVNLSEIQNIKSELKFVPKAEQ", "length": 88, "header": "tr|F1NJ53-1|F1NJ53_CHICK Isoform 1 of Small muscular protein OS=Gallus gallus OX=9031 GN=SMPX PE=3 SV=2 CANONICAL=F1NJ53-1" }, "isoforms": [ { "isoform_ac": "F1NJ53-1", "url": "https://www.uniprot.org/uniprotkb/F1NJ53/entry#F1NJ53-1", "sequence": { "sequence": "MSKQPASHVKAIQANINIPMGAFRPGAGHPHKRKEVTPEEVEESVPATEEEKDKKHLPGARKLPGPAVNLSEIQNIKSELKFVPKAEQ", "length": 88, "header": "tr|F1NJ53-1|F1NJ53_CHICK Isoform 1 of Small muscular protein OS=Gallus gallus OX=9031 GN=SMPX PE=3 SV=2 CANONICAL=F1NJ53-1" }, "locus": { "chromosome": "1", "start_pos": 119225377, "end_pos": 119216883, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010004300.1", "url": 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taurus", "sequence": { "sequence": "MSKQPVSNVRAIQANINIPMGAFRPGAGQPPRRKECTPEIEEGAPPTSDEEKKPIPGAKKLPGPAVNLSEIQNIKSELKYVPKAEQ", "length": 86 }, "evidence": [ { "id": "F1NJ53", "url": "https://omabrowser.org/oma/group/F1NJ53/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q925F0-1", "protein_name": "Small muscular protein", "gene_name": "Smpx", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSKQPISNVRSIQANINIPMGAFRPGAGQPPRRKESTPGTAEGAPATPEEKKPVPGMKKFPGPVVNLSEIQNVKSELKYVPKGEQ", "length": 85 }, "evidence": [ { "id": "F1NJ53", "url": "https://omabrowser.org/oma/group/F1NJ53/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9DC77-1", "protein_name": "Small muscular protein", "gene_name": "Smpx", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSKQPISNVRAIQANINIPMGAFRPGAGQPPRRKESTPETEEGAPTTSEEKKPIPGMKKFPGPVVNLSEIQNVKSELKFVPKGEQ", 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Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052536.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. 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"sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1NJC7-1", "uniprot_ac": "F1NJC7", "uniprot_id": "F1NJC7_CHICK", "mass": { "chemical_mass": 55837.0, "monoisotopic_mass": 55837.0 }, "refseq": {}, "gene_names": [ { "name": "ALDH1A1", "type": "recommended", "evidence": [ { "id": "F1NJC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NJC7" } ] } ], "protein_names": [ { "name": "retinal dehydrogenase", "type": "recommended", "evidence": [ { "id": "F1NJC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NJC7/entry#names_and_taxonomy" } ] }, { "name": "1.2.1.36", "type": "synonym", "evidence": [ { "id": "F1NJC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NJC7/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NJC7", "url": "https://www.uniprot.org/uniprotkb/F1NJC7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ALDH1A1", "url": "https://www.uniprot.org/uniprotkb/F1NJC7", "locus": { "chromosome": "Z", "start_pos": 36507176, "end_pos": 36560223, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010014104", "url": "https://www.ensembl.org/id/ENSGALG00010014104" } ] } } ], "crossref": [ { "id": "F1NJC7", "url": "https://alphafold.ebi.ac.uk/entry/F1NJC7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000015147", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000015147", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd07141", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07141", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "395264", "url": "https://www.ncbi.nlm.nih.gov/gene/395264", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR015590", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015590", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016160", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016160", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016161", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016161", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016162", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016162", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016163", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016163", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029510", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029510", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:395264", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:395264", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "VRHVMIK", "url": "https://omabrowser.org/oma/group/VRHVMIK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1NJC7", "url": "https://www.orthodb.org/?gene=F1NJC7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11699", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11699", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00171", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00171", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-5365859", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5365859", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-70350", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-70350", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-71384", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-71384", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_989908", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989908", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "42080", "url": "https://www.rhea-db.org/rhea/42080", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "F1NJC7", "url": "https://www.uniprot.org/uniprotkb/F1NJC7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NJC7-1", "url": "https://www.uniprot.org/uniprotkb/F1NJC7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKKQGSPSNPAPVLPALPEPLKDLKIKYTKIFINNEWHDSVSGKKFEVFNPANEEKICEVAEGDKADIDKAVKAARKAFELGSPWRTMDASERGRLLNKLADLVERDRLTLATMEAIDGGKLFSTAYLMDLGACIKTIRYCAGWADKIHGRTVPMDGNFFTFTRHEPVGVCGQIIPWNFPLVMFIWKIAPALCCGNTVVVKPAEQTPLSALYMGSLIKEAGFPPGVVNIVPGFGPTAGAAISHHMDIDKVSFTGSTEVGKLIKEAAGKTNLKRVTLELGGKSPNIIFADADLDEAVEFAHIGLFYHQGQCCIAGSRIFVEEPIYDEFVRRSIERAKKYTLGDPLLPGVQQGPQIDKEQFQKILDLIESGKKEGAKLECGGGPWGNKGYFIQPTVFSNVTDDMRIAKEEIFGPVQQIMKFKTIDEVIKRANNTTYGLAAAVFTKDIDKALTFASALQAGTVWVNCYSAFSAQCPFGGFKMSGNGRELGEYGLQEYTEVKTVTIKIPQKNS", "length": 509, "header": "tr|F1NJC7-1|F1NJC7_CHICK Isoform 1 of retinal dehydrogenase OS=Gallus gallus OX=9031 GN=ALDH1A1 PE=1 SV=2 CANONICAL=F1NJC7-1" }, "isoforms": [ { "isoform_ac": "F1NJC7-1", "url": "https://www.uniprot.org/uniprotkb/F1NJC7/entry#F1NJC7-1", "sequence": { "sequence": "MKKQGSPSNPAPVLPALPEPLKDLKIKYTKIFINNEWHDSVSGKKFEVFNPANEEKICEVAEGDKADIDKAVKAARKAFELGSPWRTMDASERGRLLNKLADLVERDRLTLATMEAIDGGKLFSTAYLMDLGACIKTIRYCAGWADKIHGRTVPMDGNFFTFTRHEPVGVCGQIIPWNFPLVMFIWKIAPALCCGNTVVVKPAEQTPLSALYMGSLIKEAGFPPGVVNIVPGFGPTAGAAISHHMDIDKVSFTGSTEVGKLIKEAAGKTNLKRVTLELGGKSPNIIFADADLDEAVEFAHIGLFYHQGQCCIAGSRIFVEEPIYDEFVRRSIERAKKYTLGDPLLPGVQQGPQIDKEQFQKILDLIESGKKEGAKLECGGGPWGNKGYFIQPTVFSNVTDDMRIAKEEIFGPVQQIMKFKTIDEVIKRANNTTYGLAAAVFTKDIDKALTFASALQAGTVWVNCYSAFSAQCPFGGFKMSGNGRELGEYGLQEYTEVKTVTIKIPQKNS", "length": 509, "header": "tr|F1NJC7-1|F1NJC7_CHICK Isoform 1 of retinal dehydrogenase OS=Gallus gallus OX=9031 GN=ALDH1A1 PE=1 SV=2 CANONICAL=F1NJC7-1" }, "locus": { "chromosome": "Z", "start_pos": 36541040, "end_pos": 36507240, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033863.1", "url": "https://www.ensembl.org/id/ENSGALT00010033863.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019914.1", "url": "https://www.ensembl.org/id/ENSGALP00010019914.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 236, "start_aa": "Thr", "end_pos": 236, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr236", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:395264", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:395264", "resource": "KEGG Pathway" }, { "id": "R-GGA-5365859", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5365859", "resource": "Reactome", "description": "RA biosynthesis pathway" }, { "id": "R-GGA-70350", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-70350", "resource": "Reactome", "description": "Fructose catabolism" }, { "id": "R-GGA-71384", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-71384", "resource": "Reactome", "description": "Ethanol oxidation" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A9J7FNL7-1", "protein_name": "aldehyde dehydrogenase (NAD(+))", "gene_name": "LOC100768654", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSQPEVPAPLANLKIQYTKIFINNEWHDSVSGKKFPVINPATEEVICHVEEGDKADVDKAVKAARQAFQIGSPWRTMDASERGRLLFKLADLMERDRLLLATLEAINGGKVFASSYLFDLGGCIKALKYCAGWADKVHGQTIPSDGDIFTYTRREPIGVCGQIIPWNFPLLMFIWKIGPALSCGNTVIVKPAEQTPLTALYMASLIKEAGFPPGVVNIVPGYGPTAGAAISSHMDIDKVAFTGSTQVGKLIKEAAGKSNLKRVTLELGGKSPCIVFADADLDTAIEFAHNGVFYHQGQCCVAASRLFVEESIYDEFVRRSVERAKKYVLGNPLNTGINQGPQIDKEQHEKILDLIESGKKEGAKLECGGGRWGNKGYFVQPTVFSNVTDDMRIAKEEIFGPVQQIMKFKSLDDVIKRANNTSYGLAAGVFTKDVDKAITVSSALQAGVVWVNCYMMLSPQCPFGGFKMSGNGRELGEHGIYEYTELKTVAMKISQKNS", "length": 498 }, "evidence": [ { "id": "F1NJC7", "url": "https://omabrowser.org/oma/group/F1NJC7/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "I3LRS5-1", "protein_name": "Aldehyde dehydrogenase 1A1", "gene_name": "ALDH1A1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSSSAMPDIPVPLTNLKFQYTKIFINNEWHNSVSGKKFPVFNPATEEKLCEVEEGDKEDVDKAVKAARQAFQIGSPWRTMDASERGQLINKLADLIERDRLLLATMESMNGGKLFSNAYLMDLGGCIRTLRYCAGWADKIHGRTIPMDGNFFTYTRSEPIGVCGQIIPWNFPLVMLIWKIGPALSCGNTVVVKPAEQTPLTALHVASLIKEAGFPPGVVNIVPGYGPTAGAAISSHMDVDKVAFTGSTQVGKMIKEAAGKSNLKRVTLELGGKSPCIVFADADLDAAVEFAHHGLFYHQGQCCIAASRLFVEESIYNEFVRKSVERAKKYVLGNPLTPGVNQGPQIDKEQYEKILDLIESGKKEGAKLECGGGPWGNKGYFIQPTVFSNVTDEMRIAKEEIFGPVQQIMKFKSLDDVIKRANNTLYGLSAGIFTKDIDKAITVSSALQSGTVWVNCYGVLSAHCPFGGFKMSGNGRELGEYGLHEYTEIKTVTIKISQKNS", "length": 501 }, "evidence": [ { "id": "F1NJC7", "url": "https://omabrowser.org/oma/group/F1NJC7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P00352-1", "protein_name": "Aldehyde dehydrogenase 1A1", "gene_name": "ALDH1A1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSSSGTPDLPVLLTDLKIQYTKIFINNEWHDSVSGKKFPVFNPATEEELCQVEEGDKEDVDKAVKAARQAFQIGSPWRTMDASERGRLLYKLADLIERDRLLLATMESMNGGKLYSNAYLNDLAGCIKTLRYCAGWADKIQGRTIPIDGNFFTYTRHEPIGVCGQIIPWNFPLVMLIWKIGPALSCGNTVVVKPAEQTPLTALHVASLIKEAGFPPGVVNIVPGYGPTAGAAISSHMDIDKVAFTGSTEVGKLIKEAAGKSNLKRVTLELGGKSPCIVLADADLDNAVEFAHHGVFYHQGQCCIAASRIFVEESIYDEFVRRSVERAKKYILGNPLTPGVTQGPQIDKEQYDKILDLIESGKKEGAKLECGGGPWGNKGYFVQPTVFSNVTDEMRIAKEEIFGPVQQIMKFKSLDDVIKRANNTFYGLSAGVFTKDIDKAITISSALQAGTVWVNCYGVVSAQCPFGGFKMSGNGRELGEYGFHEYTEVKTVTVKISQKNS", "length": 501 }, "evidence": [ { "id": "F1NJC7", "url": "https://omabrowser.org/oma/group/F1NJC7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P54114-1", "protein_name": "Aldehyde dehydrogenase [NAD(P)+] 2", "gene_name": "ALD3", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MPTLYTDIEIPQLKISLKQPLGLFINNEFCPSSDGKTIETVNPATGEPITSFQAANEKDVDKAVKAARAAFDNVWSKTSSEQRGIYLSNLLKLIEEEQDTLAALETLDAGKPFHSNAKQDLAQIIELTRYYAGAVDKFNMGETIPLTFNKFAYTLKVPFGVVAQIVPWNYPLAMACRKMQGALAAGNTVIIKPAENTSLSLLYFATLIKKAGFPPGVVNVIPGYGSVVGKALGTHMDIDKISFTGSTKVGGSVLEASGQSNLKDITLECGGKSPALVFEDADLDKAIEWVANGIFFNSGQICTANSRVYVQSSIYDKFVEKFKETAKKEWDVAGKFDPFDEKCIVGPVISSTQYDRIKSYIERGKKEEKLDMFQTSEFPIGGAKGYFIPPTIFTDVPETSKLLRDEIFGPVVVVSKFTNYDDALKLANDTCYGLASAVFTKDVKKAHMFARDIKAGTVWINQTNQEEAKVPFGGFKMSGIGRESGDTGVDNYLQIKSVHVDLSLDK", "length": 506 }, "evidence": [ { "id": "F1NJC7", "url": "https://omabrowser.org/oma/group/F1NJC7/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F1NJC7", "url": "https://www.uniprot.org/uniprotkb/F1NJC7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "lipid metabolic process", "id": "GO:0006629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006629", "evidence": [ { "database": "UniProtKB", "id": "F1NJC7", "url": "https://www.uniprot.org/uniprotkb/F1NJC7" } ], "pmid": "" }, { "name": "aldehyde metabolic process", "id": "GO:0006081", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006081", "evidence": [ { "database": "UniProtKB", "id": "F1NJC7", "url": "https://www.uniprot.org/uniprotkb/F1NJC7" } ], "pmid": "" }, { "name": "fructosamine catabolic process", "id": "GO:0030392", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030392", "evidence": [ { "database": "UniProtKB", "id": "F1NJC7", "url": "https://www.uniprot.org/uniprotkb/F1NJC7" } ], "pmid": "" }, { "name": "cellular detoxification of aldehyde", "id": "GO:0110095", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0110095", "evidence": [ { "database": "UniProtKB", "id": "F1NJC7", "url": "https://www.uniprot.org/uniprotkb/F1NJC7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "retinal dehydrogenase (NAD+) activity", "id": "GO:0001758", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001758", "evidence": [ { "database": "UniProtKB", "id": "F1NJC7", "url": "https://www.uniprot.org/uniprotkb/F1NJC7" } ], "pmid": "" }, { "name": "benzaldehyde dehydrogenase (NAD+) activity", "id": "GO:0018479", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0018479", "evidence": [ { "database": "UniProtKB", "id": "F1NJC7", "url": "https://www.uniprot.org/uniprotkb/F1NJC7" } ], "pmid": "" }, { "name": "3-deoxyglucosone dehydrogenase activity", "id": "GO:0106373", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0106373", "evidence": [ { "database": "UniProtKB", "id": "F1NJC7", "url": "https://www.uniprot.org/uniprotkb/F1NJC7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 397, "end_pos": 399, "annotation": "n_glycosylation_sequon" }, { "start_pos": 430, "end_pos": 432, "annotation": "n_glycosylation_sequon" }, { "start_pos": 431, "end_pos": 433, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "42080", "name": "", "equation": "all-trans-retinal + NAD(+) + H2O = all-trans-retinoate + NADH + 2 H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0ZT16-1", "O93344-1", "P27463-1", "A0A8V0YC05-1", "F1NJC7-1", "A0A8V0Z2F8-1" ], "evidence": [ { "id": "42080", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/42080" } ] }, { "id": "R-GGA-5362522", "name": "ALDHs oxidise atRAL to atRA", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [ "R-ALL-5334816" ], "enzyme_list": [ "F1NJC7-1", "A0A8V0ZT16-1" ], "evidence": [ { "id": "R-GGA-5362522", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5362522" } ] }, { "id": "R-GGA-6813749", "name": "ALDH1A1 oxidises GA to DGA", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1NJC7-1" ], "evidence": [ { "id": "R-GGA-6813749", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6813749" } ] }, { "id": "R-GGA-71691", "name": "acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic]", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1NJC7-1" ], "evidence": [ { "id": "R-GGA-71691", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-71691" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-5334816", "participant_name": "atRA [cytosol]", "crossref": [ { "id": "C00777", "database": "COMPOUND", "url": "" }, { "id": "ZINC000012358651", "database": "ZINC", "url": "" }, { "id": "HMDB0001852", "database": "HMDB Metabolite", "url": "" }, { "id": "2644", "database": "Guide to Pharmacology - Ligands", "url": "" }, { "id": "15367", "database": "ChEBI", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A0A8V0YC05", "gene_name": "ALDH1L2", "activity": [ { "ec_number": "1.5.1.6", "activity": "(6R)-10-formyltetrahydrofolate + NADP(+) + H2O = (6S)-5,6,7,8-tetrahydrofolate + CO2 + NADPH + H(+).", "evidence": [ { "id": "A0A8V0YC05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC05" } ] }, { "ec_number": "1.5.1.6", "activity": "", "evidence": [ { "id": "A0A8V0YC05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC05" } ] } ] }, { "uniprot_ac": "A0A8V0Z2F8", "gene_name": "ALDH1A3", "activity": [ { "ec_number": "1.2.1.36", "activity": "all-trans-retinal + NAD(+) + H2O = all-trans-retinoate + NADH + 2 H(+).", "evidence": [ { "id": "A0A8V0Z2F8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2F8" } ] }, { "ec_number": "1.2.1.36", "activity": "", "evidence": [ { "id": "A0A8V0Z2F8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2F8" } ] } ] }, { "uniprot_ac": "A0A8V0ZT16", "gene_name": "ALDH1A2", "activity": [ { "ec_number": "1.2.1.36", "activity": "all-trans-retinal + NAD(+) + H2O = all-trans-retinoate + NADH + 2 H(+).", "evidence": [ { "id": "A0A8V0ZT16", "database": 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"ec_number": "1.2.1.36", "activity": "", "evidence": [ { "id": "O93344", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O93344" } ] } ] }, { "uniprot_ac": "P27463", "gene_name": "ALDH1A1", "activity": [ { "ec_number": "1.2.1.36", "activity": "all-trans-retinal + NAD(+) + H2O = all-trans-retinoate + NADH + 2 H(+).", "evidence": [ { "id": "P27463", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P27463" } ] }, { "ec_number": "1.2.1.19", "activity": "4-aminobutanal + NAD(+) + H2O = 4-aminobutanoate + NADH + 2 H(+).", "evidence": [ { "id": "P27463", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P27463" } ] }, { "ec_number": "1.2.1.3", "activity": "acetaldehyde + NAD(+) + H2O = acetate + NADH + 2 H(+).", "evidence": [ { "id": "P27463", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P27463" } ] }, { "ec_number": "1.2.1.28", "activity": "benzaldehyde + NAD(+) + H2O = benzoate + NADH + 2 H(+).", "evidence": [ { 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{ "uniprot_canonical_ac": "F1NJF9-1", "uniprot_ac": "F1NJF9", "uniprot_id": "F1NJF9_CHICK", "mass": { "chemical_mass": 9832.0, "monoisotopic_mass": 9832.0 }, "refseq": { "ac": "XP_001233649", "name": "essential MCU regulator, mitochondrial", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001233649" }, "gene_names": [ { "name": "SMDT1", "type": "recommended", "evidence": [ { "id": "F1NJF9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NJF9" } ] }, { "name": "SMDT1", "type": "synonym", "evidence": [ { "id": "XP_001233649", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001233649" } ] } ], "protein_names": [ { "name": "Essential MCU regulator, mitochondrial", "type": "recommended", "evidence": [ { "id": "F1NJF9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NJF9/entry#names_and_taxonomy" } ] }, { "name": "Single-pass membrane protein with aspartate-rich tail 1, mitochondrial", "type": "synonym", 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This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. 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This record is derived from a genomic sequence (NC_052554.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 17, 2018 this sequence version replaced XP_001233529.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_001233529", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001233529" } ] }, { "annotation": "Calcium-binding protein that may play a role in the regulation of voltage-dependent calcium channels. May also play a role in cyclic-nucleotide-mediated signaling through the regulation of adenylate and guanylate cyclases.", "evidence": [ { "database": "UniProtKB", "id": "F1NJU0", "url": "https://www.uniprot.org/uniprotkb/F1NJU0#function" }, { "database": "UniProtKB", "id": "ARBA00045395", "url": "https://www.uniprot.org/uniprotkb/ARBA00045395#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NJU0", "url": "https://www.uniprot.org/uniprotkb/F1NJU0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "HPCA", "url": "https://www.uniprot.org/uniprotkb/F1NJU0", "locus": { "chromosome": "23", "start_pos": 5661951, "end_pos": 5658450, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010017697", "url": 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"glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P84076-1", "protein_name": "Neuron-specific calcium-binding protein hippocalcin", "gene_name": "Hpca", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGKQNSKLRPEMLQDLRENTEFSELELQEWYKGFLKDCPTGILNVDEFKKIYANFFPYGDASKFAEHVFRTFDTNSDGTIDFREFIIALSVTSRGRLEQKLMWAFSMYDLDGNGYISREEMLEIVQAIYKMVSSVMKMPEDESTPEKRTEKIFRQMDTNNDGKLSLEEFIRGAKSDPSIVRLLQCDPSSASQF", "length": 193 }, "evidence": [ { "id": "F1NJU0", "url": "https://omabrowser.org/oma/group/F1NJU0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q06AT1-1", "protein_name": "Neuron-specific calcium-binding protein hippocalcin", "gene_name": "HPCA", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGKQNSKLRPEMLQDLRENTEFSELELQEWYKGFLKDCPTGILNVDEFKKIYANFFPYGDASKFAEHVFRTFDTNSDGTIDFREFIIALSVTSRGRLEQKLMWAFSMYDLDGNGYISREEMLEIVQAIYKMVSSVMKMPEDESTPEKRTEKIFRQMDTNNDGKLSLEEFIRGAKSDPSIVRLLQCDPSSASQF", "length": 193 }, "evidence": [ { "id": "F1NJU0", "url": "https://omabrowser.org/oma/group/F1NJU0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q4PL64-1", "protein_name": "Neuron-specific calcium-binding protein hippocalcin", "gene_name": "HPCA", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGKQNSKLRPEMLQDLRENTEFSELELQEWYKGFLKDCPTGILNVDEFKKIYANFFPYGDASKFAEHVFRTFDTNSDGTIDFREFIIALSVTSRGRLEQKLMWAFSMYDLDGNGYISREEMLEIVQAIYKMVSSVMKMPEDESTPEKRTEKIFRQMDTNNDGKLSLEEFIRGAKSDPSIVRLLQCDPSSASQF", "length": 193 }, "evidence": [ { "id": "F1NJU0", "url": "https://omabrowser.org/oma/group/F1NJU0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "actin binding", "id": "GO:0003779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003779", "evidence": [ { "database": "UniProtKB", "id": "F1NJU0", "url": "https://www.uniprot.org/uniprotkb/F1NJU0" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "F1NJU0", "url": "https://www.uniprot.org/uniprotkb/F1NJU0" } ], "pmid": "" }, { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "F1NJU0", "url": "https://www.uniprot.org/uniprotkb/F1NJU0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F1NJU0", "url": "https://www.uniprot.org/uniprotkb/F1NJU0" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "F1NJU0", "url": "https://www.uniprot.org/uniprotkb/F1NJU0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "cellular response to calcium ion", "id": "GO:0071277", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071277", "evidence": [ { "database": "UniProtKB", "id": "F1NJU0", "url": "https://www.uniprot.org/uniprotkb/F1NJU0" } ], "pmid": "" }, { "name": "regulation of signal transduction", "id": "GO:0009966", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009966", "evidence": [ { "database": "UniProtKB", "id": "F1NJU0", "url": "https://www.uniprot.org/uniprotkb/F1NJU0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1NJU0-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 193, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1NJU0-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1NJU0" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1NJU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NJU0" }, { "id": "PS50222", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50222" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "EF-hand", "eco_id": "ECO_0000259", "start_pos": 60, "end_pos": 95, "start_aa": "Asp", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1NJU7-1", "uniprot_ac": "F1NJU7", "uniprot_id": "F1NJU7_CHICK", "mass": { "chemical_mass": 60147.0, "monoisotopic_mass": 60147.0 }, "refseq": { "ac": "NP_001384328", "name": "tyrosine--tRNA ligase, cytoplasmic", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384328" }, "gene_names": [ { "name": "YARS", "type": "recommended", "evidence": [ { "id": "F1NJU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NJU7" } ] }, { "name": "YARS1", "type": "synonym", "evidence": [ { "id": "NP_001384328", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384328" } ] }, { "name": "YARS", "type": "synonym", "evidence": [ { "id": "NP_001384328", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384328" } ] } ], "protein_names": [ { "name": "Tyrosine--tRNA ligase", "type": "recommended", "evidence": [ { "id": "F1NJU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NJU7/entry#names_and_taxonomy" } ] }, { "name": "6.1.1.1", "type": "synonym", "evidence": [ { "id": "F1NJU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NJU7/entry#names_and_taxonomy" } ] }, { "name": "Tyrosyl-tRNA synthetase", "type": "synonym", "evidence": [ { "id": "F1NJU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NJU7/entry#names_and_taxonomy" } ] }, { "name": "tyrRS", "type": "synonym", "evidence": [ { "id": "NP_001384328", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384328" } ] }, { "name": "tyrosine--tRNA ligase, cytoplasmic", "type": "synonym", "evidence": [ { "id": "NP_001384328", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384328" } ] }, { "name": "tyrosyl--tRNA ligase", "type": "synonym", "evidence": [ { "id": "NP_001384328", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384328" } ] }, { "name": "tyrosyl-tRNA synthetase, cytoplasmic", "type": "synonym", "evidence": [ { "id": "NP_001384328", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384328" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ720626.1, HAEK01000200.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA103992290, SAMEA103992323 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AJ720626.1 and BU377452.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001384328", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384328" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NJU7", "url": "https://www.uniprot.org/uniprotkb/F1NJU7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "YARS", "url": "https://www.uniprot.org/uniprotkb/F1NJU7", "locus": { "chromosome": "23", "start_pos": 5628098, "end_pos": 5632859, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010017678", "url": "https://www.ensembl.org/id/ENSGALG00010017678" } ] } } ], "crossref": [ { "id": "F1NJU7", "url": "https://alphafold.ebi.ac.uk/entry/F1NJU7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000003563", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000003563", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00805", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00805", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd02799", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02799", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "419666", "url": "https://www.ncbi.nlm.nih.gov/gene/419666", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002305", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002305", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002307", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002307", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002547", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002547", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012340", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012340", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014729", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014729", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051270", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051270", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "RKIHMLA", "url": "https://omabrowser.org/oma/group/RKIHMLA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z413", "url": "https://www.orthodb.org/?gene=A0A8V0Z413", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NJU7", "url": "https://www.orthodb.org/?gene=F1NJU7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11586", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11586", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11586:SF43", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11586:SF43", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00579", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00579", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01588", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01588", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001384328", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384328", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "10220", "url": "https://www.rhea-db.org/rhea/10220", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0Z413", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z413", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z413-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z413-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NJU7", "url": "https://www.uniprot.org/uniprotkb/F1NJU7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NJU7-1", "url": "https://www.uniprot.org/uniprotkb/F1NJU7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQPGHAAAAMETASGPQEKYQLITRNLQEVLGEDKLMAILKEREVKIYWGTATTGKPHVAYFVPMSKIADFLKAGCEVTILFADLHAYLDNMKAPWELLELRTRYYEHVIKAMLESIGVPLEKLKFIRGTDYQLSKEYTLDVYRLSSVVTQHDAKKAGAEVVKQVEHPLLSGLLYPGLQALDEEYLKVDAQFGGVDQRKIFTFAEKYLPSLGYAKRIHLMNPMVPGLTGSKMSSSEEDSKIDLLDRKEDVKKKLKKAFCEPGNIENNGVLSFIKHVLFPLKSEFVILREEKWGGNKTYTAYETLEKDFAEQVVHPGDLKNSVEVALNKLLDPIREKFNSPELKKLTNAAYPNPSKAKPAEKGTKNSEPETIVPSRLDIRVGKVVSVEKHPDADSLYVEKIDVGEPEPRTVVSGLVQFVPKEQLQDRLVVLLCNLKPQKMRGVESQGMVLCASSVGEPRQVEPLDPPAECCAGERVYVEGYEDGEPDDELKPKKKVFEKLQADFRISEDCIAQWKERNFLTKLGSISCKSLKGGSIS", "length": 536, "header": "tr|F1NJU7-1|F1NJU7_CHICK Isoform 1 of Tyrosine--tRNA ligase OS=Gallus gallus OX=9031 GN=YARS PE=1 SV=3 CANONICAL=F1NJU7-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z413-1", "url": "https://www.uniprot.org/uniprotkb/F1NJU7/entry#A0A8V0Z413-1", "sequence": { "sequence": "MQPGHAAAAMETASGPQEKYQLITRNLQEVLGEDKLMAILKEREVKIYWGTATTGKPHVAYFVPMSKIADFLKAGCEVTILFADLHAYLDNMKAPWELLELRTRYYEHVIKAMLESIGVPLEKLKFIRGTDYQLSKEYTLDVYRLSSVVTQHDAKKAGAEVVKQVEHPLLSGLLYPGLQALDEEYLKVDAQFGGVDQRKIFTFAEKDSKIDLLDRKEDVKKKLKKAFCEPGNIENNGVLSFIKHVLFPLKSEFVILREEKWGGNKTYTAYETLEKDFAEQVVHPGDLKNSVEVALNKLLDPIREKFNSPELKKLTNAAYPNPSKAKPAEKGTKNSEPETIVPSRLDIRVGKVVSVEKHPDADSLYVEKIDVGEPEPRTVVSGLVQFVPKEQLQDRLVVLLCNLKPQKMRGVESQGMVLCASSVGEPRQVEPLDPPAECCAGERVYVEGYEDGEPDDELKPKKKVFEKLQADFRISEDCIAQWKERNFLTKLGSISCKSLKGGSIS", "length": 505, "header": "tr|A0A8V0Z413-1|A0A8V0Z413_CHICK Computationally mapped isoform of Tyrosine--tRNA ligase OS=Gallus gallus OX=9031 GN=YARS PE=1 SV=1 CANONICAL=F1NJU7-1" }, "locus": { "chromosome": "23", "start_pos": 5632841, "end_pos": 5628782, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042748.1", "url": "https://www.ensembl.org/id/ENSGALT00010042748.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025238.1", "url": "https://www.ensembl.org/id/ENSGALP00010025238.1" } ] } }, { "isoform_ac": "F1NJU7-1", "url": "https://www.uniprot.org/uniprotkb/F1NJU7/entry#F1NJU7-1", "sequence": { "sequence": "MQPGHAAAAMETASGPQEKYQLITRNLQEVLGEDKLMAILKEREVKIYWGTATTGKPHVAYFVPMSKIADFLKAGCEVTILFADLHAYLDNMKAPWELLELRTRYYEHVIKAMLESIGVPLEKLKFIRGTDYQLSKEYTLDVYRLSSVVTQHDAKKAGAEVVKQVEHPLLSGLLYPGLQALDEEYLKVDAQFGGVDQRKIFTFAEKYLPSLGYAKRIHLMNPMVPGLTGSKMSSSEEDSKIDLLDRKEDVKKKLKKAFCEPGNIENNGVLSFIKHVLFPLKSEFVILREEKWGGNKTYTAYETLEKDFAEQVVHPGDLKNSVEVALNKLLDPIREKFNSPELKKLTNAAYPNPSKAKPAEKGTKNSEPETIVPSRLDIRVGKVVSVEKHPDADSLYVEKIDVGEPEPRTVVSGLVQFVPKEQLQDRLVVLLCNLKPQKMRGVESQGMVLCASSVGEPRQVEPLDPPAECCAGERVYVEGYEDGEPDDELKPKKKVFEKLQADFRISEDCIAQWKERNFLTKLGSISCKSLKGGSIS", "length": 536, "header": "tr|F1NJU7-1|F1NJU7_CHICK Isoform 1 of Tyrosine--tRNA ligase OS=Gallus gallus OX=9031 GN=YARS PE=1 SV=3 CANONICAL=F1NJU7-1" }, "locus": { "chromosome": "23", "start_pos": 5632841, "end_pos": 5628782, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042746.1", "url": "https://www.ensembl.org/id/ENSGALT00010042746.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025236.1", "url": "https://www.ensembl.org/id/ENSGALP00010025236.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2LU27-1", "protein_name": "Tyrosine--tRNA ligase", "gene_name": "Yars1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MQPEGTGVTVPGTRRRRRARKGRGCRLSAGSGESGAMGDAPSPEEKLHLITRNLQEVLGEEKLKEILKERELKVYWGTATTGKPHVAYFVPMSKIADFLKAGCEVTILFADLHAYLDNMKAPWELLELRTSYYENVIKAMLESIGVPLEKLKFIKGTDYQLSKEYTLDVYRLSSVVTQHDAKKAGAEVVKQVEHPLLSGLLYPGLQALDEEYLKVDAQFGGVDQRKIFTFAEKYLPALGYSKRVHLMNPMVPGLTGSKMSSSEEESKIDLLDRKEDVKKKLKKAFCEPGNVENNGVLSFIKHVLFPLKSEFVILRDEKWGGNKTYTVYLELEKDFAAEVVHPGDLKNSVEVALNKLLDPIREKFNTPALKKLASAAYPDPPKQKPTAKGPAKNSEPEEIIPSRLDIRVGKIVSVEKHPDADSLYVEKIDVGEAEPRTVVSGLVQFVPKEELQDRLVVVLCNLKPQKMRGVDSQGMLLCASIEGVSRQVEPLDPPEGSAPGERVFVKGYEKGQPDEELKPKKKVFEKLQADFRISEECIAQWKQTNFMTKLGCISCKSLKGGNIS", "length": 564 }, "evidence": [ { "id": "F1NJU7", "url": "https://omabrowser.org/oma/group/F1NJU7/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "F1MHM5-1", "protein_name": "Tyrosine--tRNA ligase", "gene_name": "YARS1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGDSLSPEEKLSLITRNLQEVLGEEKLKEILKERELKVYWGTATTGKPHVAYFVPMSKIADFLKAGCEVTILFADLHAYLDNMKAPWELLELRTSYYENVIKAMLESIGVPLEKLRFIKGTDYQLSKEYTLDVYRLSSVVTQHDAKKAGAEVVKQVEHPLLSGLLYPGLQALDEEYLKVDAQFGGVDQRKIFTFAEKYLPALGYSKRIHLMNPMVPGLTGSKMSSSEEESKIDLLDRKEDVKKKLKKAFCEPGNVENNGVLAFIRHVLFPLKSEFVILRDEKWGGNKTYTAYLDLEKDFADEVVHPGDLKNSVEVALNKLLDPIREKFNTPALKKLSSAAYPDPSKQKPAVKGPAKNSEPEEVIPSRLDIRVGKVISVDKHPDADSLYVEKIDVGEAEPRTVVSGLVQFVPKEELQDRLVVVLCNLKPQKMRGVESQGMLLCASVEGVNRKVEPLDPPAGSAPGERVFVKGYEKGQPDEELKPKKKVFEKLQADFKISDEYIAQWKQTNFMTKLGSVSCKSLKGGNIS", "length": 528 }, "evidence": [ { "id": "F1NJU7", "url": "https://omabrowser.org/oma/group/F1NJU7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "I3L804-1", "protein_name": "Tyrosine--tRNA ligase", "gene_name": "YARS1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGDALSPEEKLHLITRNLQEVLGEEKLKEILKERELKVYWGTATTGKPHVAYFVPMSKIADFLKAGCEVTILFADLHAYLDNMKAPWELLELRTSYYENVIKAMLESIGVPLEKLKFIKGTDYQLSKEYTLDVYRLSSVVTQHDAKKAGAEVVKQVEHPLLSGLLYPGLQALDEEYLKVDAQFGGVDQRKIFTFAEKYLPALGYSKRVHLMNPMVPGLTGSKMSSSEEESKIDLLDRKEDVKKKLKKAFCEPGNVDNNGVLSFIKHVLFPLKSEFVILRDEKWGGNKTYTAYSDLEKDFADEVVHPGDLKNSVEVALNKLLDPIREKFNTPALKKLSSAAYPDPSKQKPVAKGPAKNSEPEEVIPSRLDIRVGRVISVDKHPDADSLYVEKVDVGEAEPRTVVSGLVQFVPKEDLQDRLVVVLCNLKPQKMRGIESQGMLLCASVEGVSRKVEPLDPPAGSAPGERVFVKGYEKGQPDEELKPKKKVFEKLQADFKISEECIAQWKQTNFMTKLGSISCKSLKGGNIS", "length": 528 }, "evidence": [ { "id": "F1NJU7", "url": "https://omabrowser.org/oma/group/F1NJU7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P36421-1", "protein_name": "Tyrosine--tRNA ligase, cytoplasmic", "gene_name": "TYS1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSSAATVDPNEAFGLITKNLQEVLNPQIIKDVLEVQKRHLKLYWGTAPTGRPHCGYFVPMTKLADFLKAGCEVTVLLADLHAFLDNMKAPLEVVNYRAKYYELTIKAILRSINVPIEKLKFVVGSSYQLTPDYTMDIFRLSNIVSQNDAKRAGADVVKQVANPLLSGLIYPLMQALDEQFLDVDCQFGGVDQRKIFVLAEENLPSLGYKKRAHLMNPMVPGLAQGGKMSASDPNSKIDLLEEPKQVKKKINSAFCSPGNVEENGLLSFVQYVIAPIQELKFGTNHFEFFIDRPEKFGGPITYKSFEEMKLAFKEEKLSPPDLKIGVADAINELLEPIRQEFANNKEFQEASEKGYPVATPQKSKKAKKPKNKGTKYPGATKTNEIATKLEETKL", "length": 394 }, "evidence": [ { "id": "F1NJU7", "url": "https://omabrowser.org/oma/group/F1NJU7/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P54577-1", "protein_name": "Tyrosine--tRNA ligase, cytoplasmic", "gene_name": "YARS1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGDAPSPEEKLHLITRNLQEVLGEEKLKEILKERELKIYWGTATTGKPHVAYFVPMSKIADFLKAGCEVTILFADLHAYLDNMKAPWELLELRVSYYENVIKAMLESIGVPLEKLKFIKGTDYQLSKEYTLDVYRLSSVVTQHDSKKAGAEVVKQVEHPLLSGLLYPGLQALDEEYLKVDAQFGGIDQRKIFTFAEKYLPALGYSKRVHLMNPMVPGLTGSKMSSSEEESKIDLLDRKEDVKKKLKKAFCEPGNVENNGVLSFIKHVLFPLKSEFVILRDEKWGGNKTYTAYVDLEKDFAAEVVHPGDLKNSVEVALNKLLDPIREKFNTPALKKLASAAYPDPSKQKPMAKGPAKNSEPEEVIPSRLDIRVGKIITVEKHPDADSLYVEKIDVGEAEPRTVVSGLVQFVPKEELQDRLVVVLCNLKPQKMRGVESQGMLLCASIEGINRQVEPLDPPAGSAPGEHVFVKGYEKGQPDEELKPKKKVFEKLQADFKISEECIAQWKQTNFMTKLGSISCKSLKGGNIS", "length": 528 }, "evidence": [ { "id": "F1NJU7", "url": "https://omabrowser.org/oma/group/F1NJU7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q4KM49-1", "protein_name": "Tyrosine--tRNA ligase, cytoplasmic", "gene_name": "Yars1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGDAPSPEEKLHLITRNLQEVLGEEKLKEILKERELKVYWGTATTGKPHVAYFVPMSKIADFLKAGCEVTILFADLHAYLDNMKAPWELLELRTSYYENVIKAMLESIGVPLEKLKFTKGTDYQLSKEYTLDVYRLSSLVTQHDAKKAGAEVVKQVEHPLLSGLLYPGLQALDEEYLKVDAQFGGIDQRKIFTFAEKYLPTLGYSKRVHLMNPMVPGLTGSKMSSSEEESKIDLLDRKEDVKKKLKKAFCEPGNVENNGVLSFVKHVLFPLKSEFVILRDEKWGGNKTYTIYQELEKDFAAEVVHPGDLKNSVEVALNKLLDPIREKFNTPALKKLASAAYPDPSKQKPTAKGPAKSSEPEEIIPSRLDIRVGKILSVEKHPDADSLYVEKIDVGEAEPRTVVSGLVQFVPKEELQDRLVVVLCNLKPQKMRGVDSQGMLLCASVEGVSRQVEPLDPPAGSAPGERVFVQGYEKGQPDEELKPKKKVFEKLQADFKISDDCVAQWKQTNFMTKLGFVSCKSLKGGNIS", "length": 528 }, "evidence": [ { "id": "F1NJU7", "url": "https://omabrowser.org/oma/group/F1NJU7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8S9J2-1", "protein_name": "Tyrosine--tRNA ligase 1, cytoplasmic", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MADQSSEIVNALSSEMEAVSVSSTQASSSSDGFQMSEEVEKRYKIVRSIGEECIQEEELKNLLAKKAAPICYDGFEPSGRMHIAQGVMKVINVNKMTSAGCRVKIWIADWFAQLNNKMGGDLKKIRVVGEYFQEIWKAAGMDNDKVEFLWSSEEINSKADKYWPLVMDIARKNKLPRILRCVQIMGRSETDELSAAQILYPCMQCADIFFLEADICQLGMDQRKVNVLAREYCDDIKRKNKPIILSHHMLPGLQQGQEKMSKSDPLSAIFMEDEEAEVNVKIKKAYCPPKVVKGNPCLEYIKYIILPWFDEFTVERNEEYGGNKTYKSFEDIAADYESGELHPGDLKKGLMNALNKILQPVRDHFKTDARAKNLLKQIKAYRVTR", "length": 385 }, "evidence": [ { "id": "F1NJU7", "url": "https://omabrowser.org/oma/group/F1NJU7/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q91WQ3-1", "protein_name": "Tyrosine--tRNA ligase, cytoplasmic", "gene_name": "Yars1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGDAPSPEEKLHLITRNLQEVLGEEKLKEILKERELKVYWGTATTGKPHVAYFVPMSKIADFLKAGCEVTILFADLHAYLDNMKAPWELLELRTSYYENVIKAMLESIGVPLEKLKFIKGTDYQLSKEYTLDVYRLSSVVTQHDAKKAGAEVVKQVEHPLLSGLLYPGLQALDEEYLKVDAQFGGVDQRKIFTFAEKYLPALGYSKRVHLMNPMVPGLTGSKMSSSEEESKIDLLDRKEDVKKKLKKAFCEPGNVENNGVLSFIKHVLFPLKSEFVILRDEKWGGNKTYTVYLELEKDFAAEVVHPGDLKNSVEVALNKLLDPIREKFNTPALKKLASAAYPDPSKQKPPAKGPAKNSEPEEVIPSRLDIRVGKILSVEKHPDADSLYVEKIDVGEAEPRTVVSGLVQFVPKEELQDRLVVVLCNLKPQKMRGVDSQGMLLCASVEGVSRQVEPLDPPAGSAPGERVFVQGYEKGQPDEELKPKKKVFEKLQADFKISEECIAQWKQTNFMTKLGFVSCKSLKGGNIS", "length": 528 }, "evidence": [ { "id": "F1NJU7", "url": "https://omabrowser.org/oma/group/F1NJU7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VV60-1", "protein_name": "Tyrosine--tRNA ligase", "gene_name": "TyrRS", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MVGITPAEKKALITRNLQETLGDDKLTKILAERDLKIYWGTATTGKPHVAYFVPMSKIADFLKAGCEVTILFADLHAYLDNMKAPWSLLELRTKYYEQVIKAMLSSIGVPLEKLKFVKGSDYQLSKEYTLDVYKLSSVVTQHDAKKAGAEVVKQVEYPLLSGLLYPGLQALDEEYLKVDAQFGGVDQRKIFTFSEKYLPQLGYEKRIHFMNPMVPGLAGGKMSSSEEDSKIDLLDSPANVKKKLKKAFCEPGNIADNGLLSFVKHVLFSLFKEGEGFEVNREAEHGGDVTFLKYEDLEKYYAEDKLHPGDLKATVEKYINRLLDPIRKAFENPELQKLSAAAYPPPAKVKAGAAPAAGADEDAPHRLDIRVGKVVEVARHPDADTLYVLKIDLAEAQPRTIISGLVKFVTEEELNQRLVAVLCNLKPSKMRGILSEGMVLCTSNADHTVVEPIVLPATATAGSRLSFEGFSGTPDEQLNPKKKVWEKLSADFKTNSDGLAVWKDNFLLTPEGEKLSSKLANCSIK", "length": 525 }, "evidence": [ { "id": "F1NJU7", "url": "https://omabrowser.org/oma/group/F1NJU7/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "F1NJU7", "url": "https://www.uniprot.org/uniprotkb/F1NJU7" } ], "pmid": "" }, { "name": "tRNA binding", "id": "GO:0000049", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000049", "evidence": [ { "database": "UniProtKB", "id": "F1NJU7", "url": "https://www.uniprot.org/uniprotkb/F1NJU7" } ], "pmid": "" }, { "name": "tyrosine-tRNA ligase activity", "id": "GO:0004831", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004831", "evidence": [ { "database": "UniProtKB", "id": "F1NJU7", "url": "https://www.uniprot.org/uniprotkb/F1NJU7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F1NJU7", "url": "https://www.uniprot.org/uniprotkb/F1NJU7" } ], "pmid": "" }, { "name": "nuclear body", "id": "GO:0016604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016604", "evidence": [ { "database": "UniProtKB", "id": "F1NJU7", "url": "https://www.uniprot.org/uniprotkb/F1NJU7" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1NJU7", "url": "https://www.uniprot.org/uniprotkb/F1NJU7" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1NJU7", "url": "https://www.uniprot.org/uniprotkb/F1NJU7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "response to starvation", "id": "GO:0042594", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042594", "evidence": [ { "database": "UniProtKB", "id": "F1NJU7", "url": "https://www.uniprot.org/uniprotkb/F1NJU7" } ], "pmid": "" }, { "name": "tyrosyl-tRNA aminoacylation", "id": "GO:0006437", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006437", "evidence": [ { "database": "UniProtKB", "id": "F1NJU7", "url": "https://www.uniprot.org/uniprotkb/F1NJU7" } ], "pmid": "" }, { "name": "response to stress", "id": "GO:0006950", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006950", "evidence": [ { "database": "UniProtKB", "id": "F1NJU7", "url": "https://www.uniprot.org/uniprotkb/F1NJU7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 295, "end_pos": 297, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "10220", "name": "", "equation": "tRNA(Tyr) + L-tyrosine + ATP = L-tyrosyl-tRNA(Tyr) + AMP + diphosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q5ZJ08-1", "F1NJU7-1", "A0A8V0YBV3-1" ], "evidence": [ { "id": "10220", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/10220" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A8V0YBV3", "gene_name": "YARS2", "activity": [ { "ec_number": "6.1.1.1", "activity": "tRNA(Tyr) + L-tyrosine + ATP = L-tyrosyl-tRNA(Tyr) + AMP + diphosphate + H(+).", "evidence": [ { "id": "A0A8V0YBV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBV3" } ] }, { "ec_number": "6.1.1.1", "activity": "", "evidence": [ { "id": "A0A8V0YBV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBV3" } ] } ] }, { "uniprot_ac": "F1NJU7", "gene_name": "YARS", "activity": [ { "ec_number": "6.1.1.1", "activity": "tRNA(Tyr) + L-tyrosine + ATP = L-tyrosyl-tRNA(Tyr) + AMP + diphosphate + H(+).", "evidence": [ { "id": "F1NJU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NJU7" } ] }, { "ec_number": "6.1.1.1", "activity": "", "evidence": [ { "id": "F1NJU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NJU7" } ] } ] }, { "uniprot_ac": "Q5ZJ08", "gene_name": "YARS1", "activity": [ { "ec_number": "6.1.1.1", "activity": "tRNA(Tyr) + L-tyrosine + ATP = L-tyrosyl-tRNA(Tyr) + AMP + diphosphate + H(+).", "evidence": [ { "id": "Q5ZJ08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJ08" } ] }, { "ec_number": "6.1.1.1", "activity": "", "evidence": [ { "id": "Q5ZJ08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJ08" } ] } ] } ], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1NJU7-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 536, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1NJU7-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1NJU7" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "6.1.1.1", "ec_name": "tRNA(Tyr) + L-tyrosine + ATP = L-tyrosyl-tRNA(Tyr) + AMP + diphosphate + H(+).", "evidence": [ { "id": "6.1.1.1", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:6.1.1.1" }, { "id": "6.1.1.1", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=6.1.1.1" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 295, "end_pos": 297 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1NK95-1", "uniprot_ac": "F1NK95", "uniprot_id": "F1NK95_CHICK", "mass": { "chemical_mass": 55536.0, "monoisotopic_mass": 55536.0 }, "refseq": { "ac": "XP_426210", "name": "potassium voltage-gated channel subfamily F member 1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_426210" }, "gene_names": [ { "name": "KCNF1", "type": "recommended", "evidence": [ { "id": "F1NK95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NK95" } ] }, { "name": "KCNF1", "type": "synonym", "evidence": [ { "id": "XP_426210", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_426210" } ] } ], "protein_names": [ { "name": "Voltage-gated potassium channel regulatory subunit KCNF1", "type": "recommended", "evidence": [ { "id": "F1NK95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NK95/entry#names_and_taxonomy" } ] }, { "name": "Potassium voltage-gated channel subfamily F member 1", "type": "synonym", "evidence": [ { "id": "F1NK95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NK95/entry#names_and_taxonomy" } ] }, { "name": "Voltage-gated potassium channel subunit Kv5.1", "type": "synonym", "evidence": [ { "id": "F1NK95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NK95/entry#names_and_taxonomy" } ] }, { "name": "potassium voltage-gated channel subfamily F member 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_426210", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_426210" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052534.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Nov 16, 2006 this sequence version replaced XP_426210.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_426210", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_426210" } ] }, { "annotation": "Regulatory alpha-subunit of the voltage-gated potassium (Kv) channel which, when coassembled with KCNB1 or KCNB2, can modulate their expression and their gating kinetics by acting on deactivation upon repolarization and inactivation during maintained depolarization. Accelerates inactivation but has relatively little effect on deactivation. Coexpression with KCNB1 or KCNB2 markedly slows inactivation. Each modulatory subunit has its own specific properties of regulation, and can lead to extensive inhibitions, to large changes in kinetics, and/or to large shifts in the voltage dependencies of the inactivation process. The gating kinetics depends on the nature and stoichiometry of the associated regulatory sunbunit. Fails to produce a potassium current when expressed alone.", "evidence": [ { "database": "UniProtKB", "id": "F1NK95", "url": "https://www.uniprot.org/uniprotkb/F1NK95#function" }, { "database": "UniProtKB", "id": "ARBA00060051", "url": "https://www.uniprot.org/uniprotkb/ARBA00060051#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NK95", "url": "https://www.uniprot.org/uniprotkb/F1NK95" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "KCNF1", "url": "https://www.uniprot.org/uniprotkb/F1NK95", "locus": { "chromosome": "3", "start_pos": 96763082, "end_pos": 96701012, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010002644", "url": "https://www.ensembl.org/id/ENSGALG00010002644" } ] } } ], "crossref": [ { "id": "ENSGALG00000016448", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000016448", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd18381", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18381", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "428652", "url": "https://www.ncbi.nlm.nih.gov/gene/428652", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003131", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003131", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003968", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003968", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003971", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003971", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005821", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005821", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011333", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011333", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027359", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027359", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028325", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028325", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048010", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048010", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:428652", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:428652", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "FKCIIDV", "url": "https://omabrowser.org/oma/group/FKCIIDV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1NK95", "url": "https://www.orthodb.org/?gene=F1NK95", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11537", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11537", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11537:SF171", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11537:SF171", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00520", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00520", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02214", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02214", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-1296072", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1296072", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_426210", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_426210", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1NK95", "url": "https://www.uniprot.org/uniprotkb/F1NK95", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NK95-1", "url": "https://www.uniprot.org/uniprotkb/F1NK95-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAGDFRFPDADTDVTEKNEETEIVVNVGGVRQVFYSDNLNQYPETRLAELLNCLSGGYDSIFSLCDDYDPGKREFYFDRDPDAFKCIIDVYYFGEIHMKKGICPICFKNEMEFWKVDLKFLDDCCKTHLSEKKEELEEIARRVQLILDDLGVDASESRWKRCQKYIWKFLEKPESSYPARVIAVLSFLFILISSVVMCVGTIPDMQVLDAEGNRVEHPTLDSIETACIGWFTMEYVLRLISSPNKLHFALSFMNIVDVLAILPFYVSLTLTHLGAKLMELSNVQQAVQALRIMRIARIFKLARHSSGLQTLTYALKRSFKELGLLLMYLAVGIFVFSALGYTMEQSHPDTLFKSIPQSFWWAIITMTTVGYGDIYPKTTLGKLNAAISFLCGVIAIALPIHPIINNFVRYYNKQRVLETAAKHELELMELNSAEGKAASSRSELGDLASEGKEGPFYSSRLKVSHSDTFIHLLSEEKHYRTRLQSCK", "length": 487, "header": "tr|F1NK95-1|F1NK95_CHICK Isoform 1 of Voltage-gated potassium channel regulatory subunit KCNF1 OS=Gallus gallus OX=9031 GN=KCNF1 PE=3 SV=3 CANONICAL=F1NK95-1" }, "isoforms": [ { "isoform_ac": "F1NK95-1", "url": "https://www.uniprot.org/uniprotkb/F1NK95/entry#F1NK95-1", "sequence": { "sequence": "MAGDFRFPDADTDVTEKNEETEIVVNVGGVRQVFYSDNLNQYPETRLAELLNCLSGGYDSIFSLCDDYDPGKREFYFDRDPDAFKCIIDVYYFGEIHMKKGICPICFKNEMEFWKVDLKFLDDCCKTHLSEKKEELEEIARRVQLILDDLGVDASESRWKRCQKYIWKFLEKPESSYPARVIAVLSFLFILISSVVMCVGTIPDMQVLDAEGNRVEHPTLDSIETACIGWFTMEYVLRLISSPNKLHFALSFMNIVDVLAILPFYVSLTLTHLGAKLMELSNVQQAVQALRIMRIARIFKLARHSSGLQTLTYALKRSFKELGLLLMYLAVGIFVFSALGYTMEQSHPDTLFKSIPQSFWWAIITMTTVGYGDIYPKTTLGKLNAAISFLCGVIAIALPIHPIINNFVRYYNKQRVLETAAKHELELMELNSAEGKAASSRSELGDLASEGKEGPFYSSRLKVSHSDTFIHLLSEEKHYRTRLQSCK", "length": 487, "header": "tr|F1NK95-1|F1NK95_CHICK Isoform 1 of Voltage-gated potassium channel regulatory subunit KCNF1 OS=Gallus gallus OX=9031 GN=KCNF1 PE=3 SV=3 CANONICAL=F1NK95-1" }, "locus": { "chromosome": "3", "start_pos": 96763551, "end_pos": 96763032, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010006132.1", "url": "https://www.ensembl.org/id/ENSGALT00010006132.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010003828.1", "url": "https://www.ensembl.org/id/ENSGALP00010003828.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:428652", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:428652", "resource": "KEGG Pathway" }, { "id": "R-GGA-1296072", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1296072", "resource": "Reactome", "description": "Voltage gated Potassium channels" } ], "orthologs": [ { "uniprot_canonical_ac": "D4ADX7-1", "protein_name": "Voltage-gated potassium channel regulatory subunit KCNF1", "gene_name": "Kcnf1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDASAEQSLPEPGSQDSVAGDDIEIVVNVGGVRQVLYGDLLSQYPETRLAELINCLAGGYDTIFSLCDDYDPGKREFYFDRDPDAFKCVIEVYYFGEVHMKKGICPICFKNEMDFWKVDLKFLDDCCKSHLSEKREELEEIARRVQLILDDLGVDAAEGRWRRCQKCVWKFLEKPESSCPARVVAVLSFLLILVSSVVMCMGTIPELQVVDSEGNRVEHPTLENVETACIGWFTLEYLLRLFSSPNKLHFALSFMNIVDVLAILPFYVSLTLTHLGARMMELTNVQQAVQALRIMRIARIFKLARHSSGLQTLTYALKRSFKELGLLLMYLAVGIFVFSALGYTMEQSHPETLFKSIPQSFWWAIITMTTVGYGDIYPKTTLGKLNAAISFLCGVIAIALPIHPIINNFVRYYNKQRVLETAAKHELELMELNSSSAESKPGGSRSDLDTLPPEPAAREGPSWGSRLKLSHSDTFIPLLTEEKHHRTRLQSCK", "length": 493 }, "evidence": [ { "id": "F1NK95", "url": "https://omabrowser.org/oma/group/F1NK95/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q7TSH7-1", "protein_name": "Voltage-gated potassium channel regulatory subunit KCNF1", "gene_name": "Kcnf1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDASAEQSLPEPGSQDSVAGEDIEIVVNVGGVRQVLYGDLLSQYPETRLAELINCLAGGYDTIFSLCDDYDPGKREFYFDRDPDAFKCVIEVYYFGEVHMKKGICPICFKNEMDFWKVDLKFLDDCCKSHLSEKREELEEIARRVQLILDDLGVDAAEGRWRRCQKCVWKFLEKPESSCPARVVAVLSFLLILVSSVVMCMGTIPELQVVDSEGNRVEHPTLENVETACIGWFTLEYLLRLFSSPNKLHFALSFMNIVDVLAILPFYVSLTLTHLGARMMELTNVQQAVQALRIMRIARIFKLARHSSGLQTLTYALKRSFKELGLLLMYLAVGIFVFSALGYTMEQSHPETLFKSIPQSFWWAIITMTTVGYGDIYPKTTLGKLNAAISFLCGVIAIALPIHPIINNFVRYYNKQRVLETAAKHELELMELNSSSAEGKPGGSRSDLDTLPPEPAAREGPSWGSRLKLSHSDTFIPLLTEEKHHRTRLQSCK", "length": 493 }, "evidence": [ { "id": "F1NK95", "url": "https://omabrowser.org/oma/group/F1NK95/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9H3M0-1", "protein_name": "Voltage-gated potassium channel regulatory subunit KCNF1", "gene_name": "KCNF1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDGSGERSLPEPGSQSSAASDDIEIVVNVGGVRQVLYGDLLSQYPETRLAELINCLAGGYDTIFSLCDDYDPGKREFYFDRDPDAFKCVIEVYYFGEVHMKKGICPICFKNEMDFWKVDLKFLDDCCKSHLSEKREELEEIARRVQLILDDLGVDAAEGRWRRCQKCVWKFLEKPESSCPARVVAVLSFLLILVSSVVMCMGTIPELQVLDAEGNRVEHPTLENVETACIGWFTLEYLLRLFSSPNKLHFALSFMNIVDVLAILPFYVSLTLTHLGARMMELTNVQQAVQALRIMRIARIFKLARHSSGLQTLTYALKRSFKELGLLLMYLAVGIFVFSALGYTMEQSHPETLFKSIPQSFWWAIITMTTVGYGDIYPKTTLGKLNAAISFLCGVIAIALPIHPIINNFVRYYNKQRVLETAAKHELELMELNSSSGGEGKTGGSRSDLDNLPPEPAGKEAPSCSSRLKLSHSDTFIPLLTEEKHHRTRLQSCK", "length": 494 }, "evidence": [ { "id": "F1NK95", "url": "https://omabrowser.org/oma/group/F1NK95/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "F1NK95", "url": "https://www.uniprot.org/uniprotkb/F1NK95" } ], "pmid": "" }, { "name": "voltage-gated potassium channel complex", "id": "GO:0008076", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008076", "evidence": [ { "database": "UniProtKB", "id": "F1NK95", "url": "https://www.uniprot.org/uniprotkb/F1NK95" } ], "pmid": "" }, { "name": "ciliary base", "id": "GO:0097546", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097546", "evidence": [ { "database": "UniProtKB", "id": "F1NK95", "url": "https://www.uniprot.org/uniprotkb/F1NK95" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "protein homooligomerization", "id": "GO:0051260", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051260", "evidence": [ { "database": "UniProtKB", "id": "F1NK95", "url": "https://www.uniprot.org/uniprotkb/F1NK95" } ], "pmid": "" }, { "name": "action potential", "id": "GO:0001508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001508", "evidence": [ { "database": "UniProtKB", "id": "F1NK95", "url": "https://www.uniprot.org/uniprotkb/F1NK95" } ], "pmid": "" }, { "name": "non-motile cilium assembly", "id": "GO:1905515", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905515", "evidence": [ { "database": "UniProtKB", "id": "F1NK95", "url": "https://www.uniprot.org/uniprotkb/F1NK95" } ], "pmid": "" }, { "name": "potassium ion transmembrane transport", "id": "GO:0071805", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071805", "evidence": [ { "database": "UniProtKB", "id": "F1NK95", "url": "https://www.uniprot.org/uniprotkb/F1NK95" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "potassium channel regulator activity", "id": "GO:0015459", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015459", "evidence": [ { "database": "UniProtKB", "id": "F1NK95", "url": "https://www.uniprot.org/uniprotkb/F1NK95" } ], "pmid": "" }, { "name": "voltage-gated potassium channel activity", "id": "GO:0005249", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005249", "evidence": [ { "database": "UniProtKB", "id": "F1NK95", "url": "https://www.uniprot.org/uniprotkb/F1NK95" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1NK95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NK95" }, { "id": "PF00520", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00520" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ion transport", "eco_id": "ECO_0000259", "start_pos": 180, "end_pos": 414, "start_aa": "Arg", "end_aa": "Gln", "glycosite_overlap": "" }, { "evidence": [ { "id": "F1NK95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NK95" }, { "id": "PF02214", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02214" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Potassium channel tetramerisation-type BTB", "eco_id": "ECO_0000259", "start_pos": 23, "end_pos": 124, "start_aa": "Ile", "end_aa": "Cys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] 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"database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12737:SF17", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12737:SF17", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF19420", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19420", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-203615", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-203615", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "F1NKG5", "url": "https://www.uniprot.org/uniprotkb/F1NKG5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NKG5-1", "url": "https://www.uniprot.org/uniprotkb/F1NKG5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGRGRAAGGALSAAGAGGGGSRAEPGRSDPPASPRSMAGLGGGPAAFGRCTHAVVRALPESLCRQALRSTAGPEVDFARAEREHQLYVGVLRGKLGLQVLELPADESLPDCVFVEDAAVVCEETALLTRPGAPSRRKEVEAMKRVLESLNLNMVEMVDENATLDGGDVLFTGREFFVGLSKRTNQRGAEILADTFKDYAVSTVPVHDSLHLKSFCSMAGPNLIAIGSSEAAQKALKTMQQMSDHRYDKLTVPDDAAANCIYLNIPSKGHVLLHRAPEEYPESAKVFEKLKDHMLIPIANTELEKVDGALTCCSVLINKTSEL", "length": 322, "header": "tr|F1NKG5-1|F1NKG5_CHICK Isoform 1 of Dimethylarginine dimethylaminohydrolase 1 OS=Gallus gallus OX=9031 GN= PE=1 SV=3 CANONICAL=F1NKG5-1" }, "isoforms": [ { "isoform_ac": "F1NKG5-1", "url": "https://www.uniprot.org/uniprotkb/F1NKG5/entry#F1NKG5-1", "sequence": { "sequence": "MGRGRAAGGALSAAGAGGGGSRAEPGRSDPPASPRSMAGLGGGPAAFGRCTHAVVRALPESLCRQALRSTAGPEVDFARAEREHQLYVGVLRGKLGLQVLELPADESLPDCVFVEDAAVVCEETALLTRPGAPSRRKEVEAMKRVLESLNLNMVEMVDENATLDGGDVLFTGREFFVGLSKRTNQRGAEILADTFKDYAVSTVPVHDSLHLKSFCSMAGPNLIAIGSSEAAQKALKTMQQMSDHRYDKLTVPDDAAANCIYLNIPSKGHVLLHRAPEEYPESAKVFEKLKDHMLIPIANTELEKVDGALTCCSVLINKTSEL", "length": 322, "header": "tr|F1NKG5-1|F1NKG5_CHICK Isoform 1 of Dimethylarginine dimethylaminohydrolase 1 OS=Gallus gallus OX=9031 GN= PE=1 SV=3 CANONICAL=F1NKG5-1" }, "locus": { "chromosome": "8", "start_pos": 16006940, "end_pos": 15961053, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010059738.1", "url": "https://www.ensembl.org/id/ENSGALT00010059738.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010036498.1", "url": "https://www.ensembl.org/id/ENSGALP00010036498.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-203615", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-203615", "resource": "Reactome", "description": "eNOS activation" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "dimethylargininase activity", "id": "GO:0016403", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016403", "evidence": [ { "database": "UniProtKB", "id": "F1NKG5", "url": "https://www.uniprot.org/uniprotkb/F1NKG5" } ], "pmid": "" }, { "name": "amino acid binding", "id": "GO:0016597", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016597", "evidence": [ { "database": "UniProtKB", "id": "F1NKG5", "url": "https://www.uniprot.org/uniprotkb/F1NKG5" } ], "pmid": "" }, { "name": "nitric-oxide synthase regulator activity", "id": "GO:0030235", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030235", "evidence": [ { "database": "UniProtKB", "id": "F1NKG5", "url": "https://www.uniprot.org/uniprotkb/F1NKG5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 8, "go_terms": [ { "name": "negative regulation of cell population proliferation", "id": "GO:0008285", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008285", "evidence": [ { "database": "UniProtKB", "id": "F1NKG5", "url": "https://www.uniprot.org/uniprotkb/F1NKG5" } ], "pmid": "" }, { "name": "positive regulation of nitric oxide biosynthetic process", "id": "GO:0045429", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045429", "evidence": [ { "database": "UniProtKB", "id": "F1NKG5", "url": "https://www.uniprot.org/uniprotkb/F1NKG5" } ], "pmid": "" }, { "name": "negative regulation of vascular permeability", "id": "GO:0043116", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043116", "evidence": [ { "database": "UniProtKB", "id": "F1NKG5", "url": "https://www.uniprot.org/uniprotkb/F1NKG5" } ], "pmid": "" }, { "name": "regulation of systemic arterial blood pressure", "id": "GO:0003073", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003073", "evidence": [ { "database": "UniProtKB", "id": "F1NKG5", "url": "https://www.uniprot.org/uniprotkb/F1NKG5" } ], "pmid": "" }, { "name": "citrulline metabolic process", "id": "GO:0000052", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000052", "evidence": [ { "database": "UniProtKB", "id": "F1NKG5", "url": "https://www.uniprot.org/uniprotkb/F1NKG5" } ], "pmid": "" }, { "name": "arginine metabolic process", "id": "GO:0006525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006525", "evidence": [ { "database": "UniProtKB", "id": "F1NKG5", "url": "https://www.uniprot.org/uniprotkb/F1NKG5" } ], "pmid": "" }, { "name": "L-arginine catabolic process", "id": "GO:0006527", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006527", "evidence": [ { "database": "UniProtKB", "id": "F1NKG5", "url": "https://www.uniprot.org/uniprotkb/F1NKG5" } ], "pmid": "" }, { "name": "negative regulation of cellular response to hypoxia", "id": "GO:1900038", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1900038", "evidence": [ { "database": "UniProtKB", "id": "F1NKG5", "url": "https://www.uniprot.org/uniprotkb/F1NKG5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 160, "end_pos": 162, "annotation": "n_glycosylation_sequon" }, { "start_pos": 317, "end_pos": 319, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], 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"##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052539.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004936726", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004936726" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NKV0", "url": "https://www.uniprot.org/uniprotkb/F1NKV0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "DNAJB4", "url": "https://www.uniprot.org/uniprotkb/F1NKV0", "locus": { "chromosome": "8", "start_pos": 18554515, "end_pos": 18579635, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010022186", "url": "https://www.ensembl.org/id/ENSGALG00010022186" } ] } } ], "crossref": [ { "id": "F1NKV0", "url": "https://alphafold.ebi.ac.uk/entry/F1NKV0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000008916", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000008916", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd06257", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06257", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd10747", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd10747", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "424550", "url": "https://www.ncbi.nlm.nih.gov/gene/424550", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001623", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001623", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002939", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002939", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008971", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008971", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018253", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018253", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036869", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036869", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051339", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051339", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:424550", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424550", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MGRDYYK", "url": "https://omabrowser.org/oma/group/MGRDYYK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1NKV0", "url": "https://www.orthodb.org/?gene=F1NKV0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24078", "url": 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"Protein" ] } ], "sequence": { "sequence": "MGKDYYSILGIEKGASEEDIKKAYRKQALKWHPDKNKSAHAEEKFKEIAEAYEVLSDPKKRDIYDQYGEEGLKGGAGGPDGQGGTFRYSFHGDPHATFAAFFGGTNPFEIFFGRRMPGGRDTEDMEVDGDPFGSFTSFSMNGFPRERNTVGSQIRRKQDPPVIHELKVSLEEIYHGCTKRMRISRKRLNPDGRSVRTEDKILTIEIKRGWKEGTKITFPKEGDETPNTIPADIVFIIKDKPHSHFKRDGSNIVYPVKISLREALCGSSINVPTIEGRTIPMTVNEVVKPGMRRRIIGYGLPFPKNPDQRGDLIIEFEVIFPDNISPASKEVLRRNLPVS", "length": 339, "header": "tr|F1NKV0-1|F1NKV0_CHICK Isoform 1 of DnaJ heat shock protein family (Hsp40) member B4 OS=Gallus gallus OX=9031 GN=DNAJB4 PE=1 SV=2 CANONICAL=F1NKV0-1" }, "isoforms": [ { "isoform_ac": "F1NKV0-1", "url": "https://www.uniprot.org/uniprotkb/F1NKV0/entry#F1NKV0-1", "sequence": { "sequence": "MGKDYYSILGIEKGASEEDIKKAYRKQALKWHPDKNKSAHAEEKFKEIAEAYEVLSDPKKRDIYDQYGEEGLKGGAGGPDGQGGTFRYSFHGDPHATFAAFFGGTNPFEIFFGRRMPGGRDTEDMEVDGDPFGSFTSFSMNGFPRERNTVGSQIRRKQDPPVIHELKVSLEEIYHGCTKRMRISRKRLNPDGRSVRTEDKILTIEIKRGWKEGTKITFPKEGDETPNTIPADIVFIIKDKPHSHFKRDGSNIVYPVKISLREALCGSSINVPTIEGRTIPMTVNEVVKPGMRRRIIGYGLPFPKNPDQRGDLIIEFEVIFPDNISPASKEVLRRNLPVS", "length": 339, "header": "tr|F1NKV0-1|F1NKV0_CHICK Isoform 1 of DnaJ heat shock protein family (Hsp40) member B4 OS=Gallus gallus OX=9031 GN=DNAJB4 PE=1 SV=2 CANONICAL=F1NKV0-1" }, "locus": { "chromosome": "8", "start_pos": 18562945, "end_pos": 18557804, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053977.1", "url": "https://www.ensembl.org/id/ENSGALT00010053977.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032513.1", "url": "https://www.ensembl.org/id/ENSGALP00010032513.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:424550", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424550", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "P25294-1", "protein_name": "Protein SIS1", "gene_name": "SIS1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MVKETKLYDLLGVSPSANEQELKKGYRKAALKYHPDKPTGDTEKFKEISEAFEILNDPQKREIYDQYGLEAARSGGPSFGPGGPGGAGGAGGFPGGAGGFSGGHAFSNEDAFNIFSQFFGGSSPFGGADDSGFSFSSYPSGGGAGMGGMPGGMGGMHGGMGGMPGGFRSASSSPTYPEEETVQVNLPVSLEDLFVGKKKSFKIGRKGPHGASEKTQIDIQLKPGWKAGTKITYKNQGDYNPQTGRRKTLQFVIQEKSHPNFKRDGDDLIYTLPLSFKESLLGFSKTIQTIDGRTLPLSRVQPVQPSQTSTYPGQGMPTPKNPSQRGNLIVKYKVDYPISLNDAQKRAIDENF", "length": 352 }, "evidence": [ { "id": "F1NKV0", "url": "https://omabrowser.org/oma/group/F1NKV0/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q9SU57-1", "protein_name": "DNAJ heat shock family protein", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MGVDYYNILKVNHNATEDDLKKAYKRLAMIWHPDKNPSTRRDEAEAKFKRISEAYDVLSDPQKRQIYDLYGEEGLKSGKIPNSSSSEASSSSSSSSSRYPHFHQHRPQHPPNASSFRFNPRDAEDIYAEFFGSENGGGSNNAGGRGNRAFRNGHFNTGGANGYSGEMRKVPAMENPLPVSLEDLYKGVVKKMRITRNVYDASGRMMVEAEILPIEIKPGWKKGTKLTFPKKGNEEPGIIPADIVFVVEEKPHPVYKRDGNDLLVSQEITLLEALTGKTVNLITLDGRTLMIPLTEIIKPDHEIVVPNEGMPISKEPGKKGNLKLKLSVKYPSRLTSDQKFELKRVLGGVS", "length": 350 }, "evidence": [ { "id": "F1NKV0", "url": "https://omabrowser.org/oma/group/F1NKV0/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "F1NKV0", "url": "https://www.uniprot.org/uniprotkb/F1NKV0" } ], "pmid": "" }, { "name": "protein folding", "id": "GO:0006457", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006457", "evidence": [ { "database": "UniProtKB", "id": "F1NKV0", "url": "https://www.uniprot.org/uniprotkb/F1NKV0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "F1NKV0", "url": "https://www.uniprot.org/uniprotkb/F1NKV0" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F1NKV0", "url": "https://www.uniprot.org/uniprotkb/F1NKV0" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F1NKV0", "url": "https://www.uniprot.org/uniprotkb/F1NKV0" } ], "pmid": "" }, { "name": "Z disc", "id": "GO:0030018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030018", "evidence": [ { "database": "UniProtKB", "id": "F1NKV0", "url": "https://www.uniprot.org/uniprotkb/F1NKV0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "unfolded protein binding", "id": "GO:0051082", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051082", "evidence": [ { "database": "UniProtKB", "id": "F1NKV0", "url": "https://www.uniprot.org/uniprotkb/F1NKV0" } ], "pmid": "" }, { "name": "protein-folding chaperone binding", "id": "GO:0051087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051087", "evidence": [ { "database": "UniProtKB", "id": "F1NKV0", "url": "https://www.uniprot.org/uniprotkb/F1NKV0" } ], "pmid": "" }, { "name": "ATPase activator activity", "id": "GO:0001671", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001671", "evidence": [ { "database": "UniProtKB", "id": "F1NKV0", "url": "https://www.uniprot.org/uniprotkb/F1NKV0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 323, "end_pos": 325, "annotation": "n_glycosylation_sequon" }, { "start_pos": 36, "end_pos": 38, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1NKV0-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 339, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1NKV0-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1NKV0" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 323, "end_pos": 325 }, { "start_pos": 36, "end_pos": 38 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1NL19-1", "uniprot_ac": "F1NL19", "uniprot_id": "F1NL19_CHICK", "mass": { "chemical_mass": 26802.0, "monoisotopic_mass": 26802.0 }, "refseq": { "ac": "XP_423237", "name": "ubiquitin-conjugating enzyme E2 R1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_423237" }, "gene_names": [ { "name": "CDC34", "type": "recommended", "evidence": [ { "id": "F1NL19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NL19" } ] }, { "name": "CDC34", "type": "synonym", "evidence": [ { "id": "XP_423237", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_423237" } ] } ], "protein_names": [ { "name": "E2 ubiquitin-conjugating enzyme", "type": "recommended", "evidence": [ { "id": "F1NL19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NL19/entry#names_and_taxonomy" } ] }, { "name": "2.3.2.23", "type": "synonym", "evidence": [ { "id": "F1NL19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NL19/entry#names_and_taxonomy" } ] }, { "name": "ubiquitin-conjugating enzyme E2 R1", "type": "synonym", "evidence": [ { "id": "XP_423237", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_423237" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052559.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process On Nov 16, 2006 this sequence version replaced XP_423237.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_423237", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_423237" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NL19", "url": "https://www.uniprot.org/uniprotkb/F1NL19" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CDC34", "url": "https://www.uniprot.org/uniprotkb/F1NL19", "locus": { "chromosome": "28", "start_pos": 3105938, "end_pos": 3100130, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010028473", "url": "https://www.ensembl.org/id/ENSGALG00010028473" } ] } } ], "crossref": [ { "id": "F1NL19", "url": "https://alphafold.ebi.ac.uk/entry/F1NL19", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000024332", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000024332", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd23803", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd23803", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "425483", "url": "https://www.ncbi.nlm.nih.gov/gene/425483", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000608", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000608", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016135", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016135", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023313", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023313", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050113", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050113", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:425483", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:425483", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "VNSCYGD", "url": "https://omabrowser.org/oma/group/VNSCYGD/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1NL19", "url": "https://www.orthodb.org/?gene=F1NL19", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24067", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24067", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00179", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00179", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-8866652", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8866652", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-983168", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983168", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_423237", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_423237", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1NL19", "url": "https://www.uniprot.org/uniprotkb/F1NL19", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NL19-1", "url": "https://www.uniprot.org/uniprotkb/F1NL19-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MARSLVPSSQKALLLELKGLQEEPVEGFRVNLVDEGDLYNWEVAIFGPPNTYYEGGYFKARLRFPIDYPYSPPAFRFLTKMWHPNIYETGDVCISILHPPVDDPQSGELPSERWNPTQNVRTILLSVISLLNEPNTFSPANVDASVMYRKWKESKGKDREYTDIIRKQVLGTKVDAERDGVKVPTTLAEYCVKTKTPAPDEGSDLFYDDYYEDDEMEEEADSCYGDEDDSGNEES", "length": 235, "header": "tr|F1NL19-1|F1NL19_CHICK Isoform 1 of E2 ubiquitin-conjugating enzyme OS=Gallus gallus OX=9031 GN=CDC34 PE=3 SV=3 CANONICAL=F1NL19-1" }, "isoforms": [ { "isoform_ac": "F1NL19-1", "url": "https://www.uniprot.org/uniprotkb/F1NL19/entry#F1NL19-1", "sequence": { "sequence": "MARSLVPSSQKALLLELKGLQEEPVEGFRVNLVDEGDLYNWEVAIFGPPNTYYEGGYFKARLRFPIDYPYSPPAFRFLTKMWHPNIYETGDVCISILHPPVDDPQSGELPSERWNPTQNVRTILLSVISLLNEPNTFSPANVDASVMYRKWKESKGKDREYTDIIRKQVLGTKVDAERDGVKVPTTLAEYCVKTKTPAPDEGSDLFYDDYYEDDEMEEEADSCYGDEDDSGNEES", "length": 235, "header": "tr|F1NL19-1|F1NL19_CHICK Isoform 1 of E2 ubiquitin-conjugating enzyme OS=Gallus gallus OX=9031 GN=CDC34 PE=3 SV=3 CANONICAL=F1NL19-1" }, "locus": { "chromosome": "28", "start_pos": 3105235, "end_pos": 3100285, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068945.1", "url": "https://www.ensembl.org/id/ENSGALT00010068945.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042387.1", "url": "https://www.ensembl.org/id/ENSGALP00010042387.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "gga:425483", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:425483", "resource": "KEGG Pathway" }, { "id": "R-GGA-8866652", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8866652", "resource": "Reactome", "description": "Synthesis of active ubiquitin: roles of E1 and E2 enzymes" }, { "id": "R-GGA-983168", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983168", "resource": "Reactome", "description": "Antigen processing: Ubiquitination & Proteasome degradation" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287BPQ6-1", "protein_name": "E2 ubiquitin-conjugating enzyme", "gene_name": "CDC34", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MARPLVPSSQKALLLELKGLQEEPVEGFRVTLVDEGDLYNWEVAIFGPPNTYYEGGYFKARLKFPIDYPYSPPAFRFLTKMWHPNIYETGDVCISILHPPVDDPQSGELPSERWNPTQNVRTILLSVISLLNEPNTFSPANVDASVMYRKWKESKGRDREYTDIIRKQVLGTKVDAERDGVKVPTTLAEYCVKTKAPVPDEGSDLFYDDYYEDGEAEADSCFGDDEDDSGTEES", "length": 234 }, "evidence": [ { "id": "F1NL19", "url": "https://omabrowser.org/oma/group/F1NL19/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "D4A453-1", "protein_name": "E2 ubiquitin-conjugating enzyme", "gene_name": "Cdc34", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "WETRADPAPLPHKPRPTPHPQPRPLDVTEKAPKAAAATPQRAAQPCPPLRTQASAELFRPEATAASGASETQGACAAGRGKKTTLPGVPRGRARRHIPDPVEASHRRILDPAVARRCISGPAAAARSRIRGPGVARRRIRGPKEARRRIRGREPVRRRIRGPAAAARRRVRRGPGRAEASAGRAAAPERVEPSGSPGGGGGGGAEEEGGGSPPAGARPGPSRELAPVPRPGPAPAPGPSAAAAVTAMARPLVPSSQKALLLELKGLQEEPVEGFRVTLVDEGDLYNWEVAIFGPPNTYYEGGYFKARLKFPIDYPYSPPAFRFLTKMWHPNIYETGDVCISILHPPVDDPQSGELPSERWNPTQNVRTILLSVISLLNEPNTFSPANVDASVMYRKWKESKGKDREYTDIIRKQVLGTKVDAERDGVKVPTTLAEYCVKTKAPAPDEGSDLFYDDYYEDGEVEEADSCFGDEEDDSGTEES", "length": 481 }, "evidence": [ { "id": "F1NL19", "url": "https://omabrowser.org/oma/group/F1NL19/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P49427-1", "protein_name": "Ubiquitin-conjugating enzyme E2 R1", "gene_name": "CDC34", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MARPLVPSSQKALLLELKGLQEEPVEGFRVTLVDEGDLYNWEVAIFGPPNTYYEGGYFKARLKFPIDYPYSPPAFRFLTKMWHPNIYETGDVCISILHPPVDDPQSGELPSERWNPTQNVRTILLSVISLLNEPNTFSPANVDASVMYRKWKESKGKDREYTDIIRKQVLGTKVDAERDGVKVPTTLAEYCVKTKAPAPDEGSDLFYDDYYEDGEVEEEADSCFGDDEDDSGTEES", "length": 236 }, "evidence": [ { "id": "F1NL19", "url": "https://omabrowser.org/oma/group/F1NL19/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8CFI2-1", "protein_name": "Ubiquitin-conjugating enzyme E2 R1", "gene_name": "Cdc34", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MARPLVPSSQKALLLELKGLQEEPVEGFRVTLVDEGDLYNWEVAIFGPPNTYYEGGYFKARLKFPIDYPYSPPAFRFLTKMWHPNIYETGDVCISILHPPVDDPQSGELPSERWNPTQNVRTILLSVISLLNEPNTFSPANVDASVMYRKWKESKGKDREYTDIIRKQVLGTKVDAERDGVKVPTTLAEYCVKTKAPAPDEGSDLFYDDYYEDGEVEEADSCFGDEEDDSGTEES", "length": 235 }, "evidence": [ { "id": "F1NL19", "url": "https://omabrowser.org/oma/group/F1NL19/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "F1NL19", "url": "https://www.uniprot.org/uniprotkb/F1NL19" } ], "pmid": "" }, { "name": "ubiquitin conjugating enzyme activity", "id": "GO:0061631", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061631", "evidence": [ { "database": "UniProtKB", "id": "F1NL19", "url": "https://www.uniprot.org/uniprotkb/F1NL19" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F1NL19", "url": "https://www.uniprot.org/uniprotkb/F1NL19" } ], "pmid": "" }, { "name": "nuclear speck", "id": "GO:0016607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016607", "evidence": [ { "database": "UniProtKB", "id": "F1NL19", "url": "https://www.uniprot.org/uniprotkb/F1NL19" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "proteasome-mediated ubiquitin-dependent protein catabolic process", "id": "GO:0043161", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043161", "evidence": [ { "database": "UniProtKB", "id": "F1NL19", "url": "https://www.uniprot.org/uniprotkb/F1NL19" } ], "pmid": "" }, { "name": "protein polyubiquitination", "id": "GO:0000209", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000209", "evidence": [ { "database": "UniProtKB", "id": "F1NL19", "url": "https://www.uniprot.org/uniprotkb/F1NL19" } ], "pmid": "" }, { "name": "ubiquitin-dependent protein catabolic process", "id": "GO:0006511", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006511", "evidence": [ { "database": "UniProtKB", "id": "F1NL19", "url": "https://www.uniprot.org/uniprotkb/F1NL19" } ], "pmid": "" }, { "name": "protein K48-linked ubiquitination", "id": "GO:0070936", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070936", "evidence": [ { "database": "UniProtKB", "id": "F1NL19", "url": "https://www.uniprot.org/uniprotkb/F1NL19" } ], "pmid": "" }, { "name": "cellular response to interferon-beta", "id": "GO:0035458", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035458", "evidence": [ { "database": "UniProtKB", "id": "F1NL19", "url": "https://www.uniprot.org/uniprotkb/F1NL19" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-GGA-8852129", "name": "UBA1 conjugates ubiquitin to cytosolic E2 enzymes", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XQR1-1", "A0A8V1AC19-1", "F1NL19-1", "R4GIV8-1", "A0A8V1A052-1", "A0A8V1A5P4-1", "A0A8V0Z1W7-1", "A0A8V1A4H7-1", "A0A8V0Y059-1", "A0A8V0YFD9-1" ], "evidence": [ { "id": "R-GGA-8852129", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8852129" } ] }, { "id": "R-GGA-8852130", "name": "UBA1 conjugates ubiquitin to nuclear E2 enzymes", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0X324-1", "A0A8V1AC19-1", "F1NL19-1", "A0A8V1A052-1", "A0A8V0Z082-1", "A0A8V1A4H7-1", "A0A8V0YFD9-1" ], "evidence": [ { "id": "R-GGA-8852130", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8852130" } ] }, { "id": "R-GGA-983140", "name": "Transfer of Ub from E2 to substrate and release of E2", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0X324-1", "A0A8V0XEM6-1", "A0A8V0XJC4-1", "A0A8V0XQR1-1", "A0A8V1AC19-1", "A0A8V1AC55-1", "A0A8V1AKB8-1", "A0A8V1ALH0-1", "F1NL19-1", "F1NRC6-1", "F1NTZ8-1", "A0A8V0YHL7-1", "A0A8V0YPW4-1", "A0A8V0YRM6-1", "A0A8V0YV22-1", "A0A8V0YVP3-1", "A0A8V0Z2L5-1", "F1NL77-1", "E1C982-1", "A0A3Q2UC96-1", "Q5ZKX6-1", "Z4YJC3-1", "A0A8V0XQU7-1", "A0A8V0Y5C9-1", "A0A8V1AL09-1", "A0A8V1AML5-1", "A0A8V1AP69-1", "F1NVY8-1", "R4GIV8-1", "A0A8V0ZJ49-1", "A0A8V0ZJV9-1", "A0A8V0ZL18-1", "A0A8V0ZM17-1", "A0A8V0ZSH4-1", "A0A8V0ZVX3-1", "A0A8V0ZW26-1", "A0A8V1A0Z6-1", "A0A8V0ZZH3-1", "A0A8V1A052-1", "A0A8V1A0X2-1", "A0A8V1A1I4-1", "A0A8V1A2W7-1", "A0A8V1A5P4-1", "A0A8V1A7T1-1", "A0A8V0XTY5-1", "A0A8V0Y5B5-1", "A0A8V0YL05-1", "A0A8V0Z082-1", "A0A8V0ZS27-1", "A0A8V1A9M0-1", "E1BZ35-1", "E1C3Q9-1", "F1NC08-1", "F1P2G0-1", "A0A8V0YY10-1", "A0A8V0YYC5-1", "A0A8V0Z1W7-1", "A0A8V0Z4C8-1", "A0A8V0Z596-1", "A0A1D5P284-1", "A0A8V0ZF21-1", "A0A3Q2U2G8-1", "A0A8V1A4H7-1", "A0A8V1A1N8-1", "A0A8V1A233-1", "A0A8V1A7P9-1", "A0A8V1ACU3-1", "A0A8V0ZSA3-1", "E1C656-1", "A0A8V0Y0Q7-1", "A0A8V0Y059-1", "A0A8V0Y5C7-1", "A0A8V0YCS7-1", "A0A8V0YDQ1-1", "A0A8V0YFD9-1", "A0A8V0YGF4-1", "A0A8V0YJK8-1", "A0A8V0YLY7-1", "A0A1D5NVE2-1", "A0A8V0ZKK3-1", "A0A8V0ZKQ3-1" ], "evidence": [ { "id": "R-GGA-983140", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983140" } ] }, { "id": "R-GGA-983152", "name": "Transfer of ubiquitin from E1 to E2", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0X324-1", "A0A8V0XQR1-1", "A0A8V1AC19-1", "F1NL19-1", "A0A8V0YPW4-1", "Q5ZKX6-1", "R4GIV8-1", "A0A8V0ZBK2-1", "A0A8V1A052-1", "A0A8V1A1I4-1", "A0A8V1A5P4-1", "A0A8V0Z082-1", "A0A8V0YY10-1", "A0A8V0Z1W7-1", "A0A8V0XNP1-1", "A0A8V1A4H7-1", "A0A8V1ACU3-1", "A0A8V0Y059-1", "A0A8V0YFD9-1", "A0A1D5NVE2-1" ], "evidence": [ { "id": "R-GGA-983152", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983152" } ] }, { "id": "R-GGA-983156", "name": "Polyubiquitination of substrate", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0X324-1", "A0A8V0XEM6-1", "A0A8V0XJC4-1", "A0A8V0XQR1-1", "A0A8V1AC19-1", "A0A8V1AC55-1", "A0A8V1AKB8-1", "A0A8V1ALH0-1", "F1NL19-1", "F1NRC6-1", "F1NTZ8-1", "A0A8V0YHL7-1", "A0A8V0YPW4-1", "A0A8V0YRM6-1", "A0A8V0YV22-1", "A0A8V0YVP3-1", "A0A8V0Z2L5-1", "F1NL77-1", "E1C982-1", "A0A3Q2UC96-1", "Q5ZKX6-1", "Z4YJC3-1", "A0A8V0XQU7-1", "A0A8V0Y5C9-1", "A0A8V1AL09-1", "A0A8V1AML5-1", "A0A8V1AP69-1", "F1NVY8-1", "R4GIV8-1", "A0A8V0ZJ49-1", "A0A8V0ZJV9-1", "A0A8V0ZL18-1", "A0A8V0ZM17-1", "A0A8V0ZSH4-1", "A0A8V0ZVX3-1", "A0A8V0ZW26-1", "A0A8V1A0Z6-1", "A0A8V0ZZH3-1", "A0A8V1A052-1", "A0A8V1A0X2-1", "A0A8V1A1I4-1", "A0A8V1A2W7-1", "A0A8V1A5P4-1", "A0A8V1A7T1-1", "A0A8V0XTY5-1", "A0A8V0Y5B5-1", "A0A8V0YL05-1", "A0A8V0Z082-1", "A0A8V0ZS27-1", "A0A8V1A9M0-1", "E1BZ35-1", "E1C3Q9-1", "F1NC08-1", "F1P2G0-1", "A0A8V0YY10-1", "A0A8V0YYC5-1", "A0A8V0Z1W7-1", "A0A8V0Z4C8-1", "A0A8V0Z596-1", "A0A1D5P284-1", "A0A8V0ZF21-1", "A0A3Q2U2G8-1", "A0A8V1A4H7-1", "A0A8V1A1N8-1", "A0A8V1A233-1", "A0A8V1A7P9-1", "A0A8V1ACU3-1", "A0A8V0ZSA3-1", "E1C656-1", "A0A8V0Y0Q7-1", "A0A8V0Y059-1", "A0A8V0Y5C7-1", "A0A8V0YCS7-1", "A0A8V0YDQ1-1", "A0A8V0YFD9-1", "A0A8V0YGF4-1", "A0A8V0YJK8-1", "A0A8V0YLY7-1", "A0A1D5NVE2-1", "A0A8V0ZKK3-1", "A0A8V0ZKQ3-1" ], "evidence": [ { "id": "R-GGA-983156", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983156" } ] }, { "id": "R-GGA-983157", "name": "Interaction of E3 with substrate and E2-Ub complex", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0X324-1", "A0A8V0XEM6-1", "A0A8V0XJC4-1", "A0A8V0XQR1-1", "A0A8V1AC19-1", "A0A8V1AC55-1", "A0A8V1AKB8-1", "A0A8V1ALH0-1", "F1NL19-1", "F1NRC6-1", "F1NTZ8-1", "A0A8V0YHL7-1", "A0A8V0YPW4-1", "A0A8V0YRM6-1", "A0A8V0YV22-1", "A0A8V0YVP3-1", "A0A8V0Z2L5-1", "F1NL77-1", "E1C982-1", "A0A3Q2UC96-1", "Q5ZKX6-1", "Z4YJC3-1", "A0A8V0XQU7-1", "A0A8V0Y5C9-1", "A0A8V1AL09-1", "A0A8V1AML5-1", "A0A8V1AP69-1", "F1NVY8-1", "R4GIV8-1", "A0A8V0ZJ49-1", "A0A8V0ZJV9-1", "A0A8V0ZL18-1", "A0A8V0ZM17-1", "A0A8V0ZSH4-1", "A0A8V0ZVX3-1", "A0A8V0ZW26-1", "A0A8V1A0Z6-1", "A0A8V0ZZH3-1", "A0A8V1A052-1", "A0A8V1A0X2-1", "A0A8V1A1I4-1", "A0A8V1A2W7-1", "A0A8V1A5P4-1", "A0A8V1A7T1-1", "A0A8V0XTY5-1", "A0A8V0Y5B5-1", "A0A8V0YL05-1", "A0A8V0Z082-1", "A0A8V0ZS27-1", "A0A8V1A9M0-1", "E1BZ35-1", "E1C3Q9-1", "F1NC08-1", "F1P2G0-1", "A0A8V0YY10-1", "A0A8V0YYC5-1", "A0A8V0Z1W7-1", "A0A8V0Z4C8-1", "A0A8V0Z596-1", "A0A1D5P284-1", "A0A8V0ZF21-1", "A0A3Q2U2G8-1", "A0A8V1A4H7-1", "A0A8V1A1N8-1", "A0A8V1A233-1", "A0A8V1A7P9-1", "A0A8V1ACU3-1", "A0A8V0ZSA3-1", "E1C656-1", "A0A8V0Y0Q7-1", "A0A8V0Y059-1", "A0A8V0Y5C7-1", "A0A8V0YCS7-1", "A0A8V0YDQ1-1", "A0A8V0YFD9-1", "A0A8V0YGF4-1", "A0A8V0YJK8-1", "A0A8V0YLY7-1", "A0A1D5NVE2-1", "A0A8V0ZKK3-1", "A0A8V0ZKQ3-1" ], "evidence": [ { "id": "R-GGA-983157", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983157" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A1D5NVE2", "gene_name": "UBE2Q1", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A1D5NVE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NVE2" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A1D5NVE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NVE2" } ] } ] }, { "uniprot_ac": "A0A1D5P284", "gene_name": "UBR2", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A1D5P284", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P284" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A1D5P284", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P284" } ] } ] }, { "uniprot_ac": "A0A3Q2U2G8", "gene_name": "TRIM9", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A3Q2U2G8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U2G8" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A3Q2U2G8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U2G8" } ] } ] }, { "uniprot_ac": "A0A3Q2UC96", "gene_name": "NEDD4L", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A3Q2UC96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UC96" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A3Q2UC96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UC96" } ] } ] }, { "uniprot_ac": "A0A8V0X324", "gene_name": "UBE2E1", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V0X324", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X324" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V0X324", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X324" } ] } ] }, { "uniprot_ac": "A0A8V0XEM6", "gene_name": "HERC2", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0XEM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEM6" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0XEM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEM6" } ] } ] }, { "uniprot_ac": "A0A8V0XJC4", "gene_name": "UBE3D", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0XJC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XJC4" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0XJC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XJC4" } ] } ] }, { "uniprot_ac": "A0A8V0XNP1", "gene_name": "UBA6", "activity": [ { "ec_number": "6.2.1.45", "activity": "ATP + ubiquitin + [E1 ubiquitin-activating enzyme]-L-cysteine = AMP + diphosphate + S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V0XNP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNP1" } ] }, { "ec_number": "6.2.1.45", "activity": "", "evidence": [ { "id": "A0A8V0XNP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNP1" } ] } ] }, { "uniprot_ac": "A0A8V0XQR1", "gene_name": "UBE2H", "activity": [ { "ec_number": "2.3.2.24", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E1 ubiquitin-activating enzyme]-L-cysteine + N(6)-monoubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0XQR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQR1" } ] }, { "ec_number": "2.3.2.24", "activity": "", "evidence": [ { "id": "A0A8V0XQR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQR1" } ] } ] }, { "uniprot_ac": "A0A8V0XQU7", "gene_name": "RNF6", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0XQU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQU7" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0XQU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQU7" } ] } ] }, { "uniprot_ac": "A0A8V0XTY5", "gene_name": "SH3RF1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0XTY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XTY5" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0XTY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XTY5" } ] } ] }, { "uniprot_ac": "A0A8V0Y059", "gene_name": "UBE2D1", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V0Y059", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y059" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V0Y059", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y059" } ] } ] }, { "uniprot_ac": "A0A8V0Y0Q7", "gene_name": "RNF144B", "activity": [ { "ec_number": "2.3.2.31", "activity": "[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-N(6)-ubiquitinyl-L-lysine.", "evidence": [ { "id": "A0A8V0Y0Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y0Q7" } ] }, { "ec_number": "2.3.2.31", "activity": "", "evidence": [ { "id": "A0A8V0Y0Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y0Q7" } ] } ] }, { "uniprot_ac": "A0A8V0Y5B5", "gene_name": "LTN1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0Y5B5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5B5" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0Y5B5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5B5" } ] } ] }, { "uniprot_ac": "A0A8V0Y5C7", "gene_name": "CBLL1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0Y5C7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5C7" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0Y5C7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5C7" } ] } ] }, { "uniprot_ac": "A0A8V0Y5C9", "gene_name": "HERC3", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0Y5C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5C9" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0Y5C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5C9" } ] } ] }, { "uniprot_ac": "A0A8V0YCS7", "gene_name": "RNF19A", "activity": [ { "ec_number": "2.3.2.31", "activity": "[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-N(6)-ubiquitinyl-L-lysine.", "evidence": [ { "id": "A0A8V0YCS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCS7" } ] }, { "ec_number": "2.3.2.31", "activity": "", "evidence": [ { "id": "A0A8V0YCS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCS7" } ] } ] }, { "uniprot_ac": "A0A8V0YDQ1", "gene_name": "WWP1", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YDQ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDQ1" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0YDQ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDQ1" } ] } ] }, { "uniprot_ac": "A0A8V0YFD9", "gene_name": "UBE2D2", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V0YFD9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFD9" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V0YFD9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFD9" } ] } ] }, { "uniprot_ac": "A0A8V0YGF4", "gene_name": "MYLIP", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YGF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGF4" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0YGF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGF4" } ] } ] }, { "uniprot_ac": "A0A8V0YHL7", "gene_name": "RNF114", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YHL7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHL7" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0YHL7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHL7" } ] } ] }, { "uniprot_ac": "A0A8V0YJK8", "gene_name": "RNF14", "activity": [ { "ec_number": "2.3.2.31", "activity": "[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-N(6)-ubiquitinyl-L-lysine.", "evidence": [ { "id": "A0A8V0YJK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJK8" } ] }, { "ec_number": "2.3.2.31", "activity": "", "evidence": [ { "id": "A0A8V0YJK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJK8" } ] } ] }, { "uniprot_ac": "A0A8V0YL05", "gene_name": "UBE3A", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YL05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL05" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0YL05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL05" } ] } ] }, { "uniprot_ac": "A0A8V0YLY7", "gene_name": "MKRN4P", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YLY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLY7" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0YLY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLY7" } ] } ] }, { "uniprot_ac": "A0A8V0YPW4", "gene_name": "UBE2J2", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V0YPW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPW4" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V0YPW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPW4" } ] } ] }, { "uniprot_ac": "A0A8V0YRM6", "gene_name": "RNF130", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YRM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRM6" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0YRM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRM6" } ] } ] }, { "uniprot_ac": "A0A8V0YV22", "gene_name": "RNF4", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YV22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YV22" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0YV22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YV22" } ] } ] }, { "uniprot_ac": "A0A8V0YVP3", "gene_name": "RBBP6", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YVP3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YVP3" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0YVP3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YVP3" } ] } ] }, { "uniprot_ac": "A0A8V0YY10", "gene_name": "UBE2D3", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V0YY10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YY10" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V0YY10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YY10" } ] } ] }, { "uniprot_ac": "A0A8V0YYC5", "gene_name": "ZNRF2", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YYC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYC5" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0YYC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYC5" } ] } ] }, { "uniprot_ac": "A0A8V0Z082", "gene_name": "UBE2B", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V0Z082", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z082" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V0Z082", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z082" } ] } ] }, { "uniprot_ac": "A0A8V0Z1W7", "gene_name": "UBE2K", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V0Z1W7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1W7" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V0Z1W7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1W7" } ] } ] }, { "uniprot_ac": "A0A8V0Z2L5", "gene_name": "TRIM63", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0Z2L5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2L5" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0Z2L5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2L5" } ] } ] }, { "uniprot_ac": "A0A8V0Z4C8", "gene_name": "MGRN1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0Z4C8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4C8" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0Z4C8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4C8" } ] } ] }, { "uniprot_ac": "A0A8V0Z596", "gene_name": "STUB1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0Z596", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z596" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0Z596", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z596" } ] } ] }, { "uniprot_ac": "A0A8V0ZBK2", "gene_name": "UBA3", "activity": [ { "ec_number": "6.2.1.64", "activity": "ATP + [NEDD8 protein] + [E1 NEDD8-activating enzyme]-L-cysteine = AMP + diphosphate + [E1 NEDD8-activating enzyme]-S-[NEDD8 protein]-yl-L-cysteine.", "evidence": [ { "id": "A0A8V0ZBK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBK2" } ] }, { "ec_number": "6.2.1.64", "activity": "", "evidence": [ { "id": "A0A8V0ZBK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBK2" } ] } ] }, { "uniprot_ac": "A0A8V0ZF21", "gene_name": "DTX3L", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZF21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF21" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0ZF21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF21" } ] } ] }, { "uniprot_ac": "A0A8V0ZJ49", "gene_name": "SMURF1", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZJ49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ49" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0ZJ49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ49" } ] } ] }, { "uniprot_ac": "A0A8V0ZJV9", "gene_name": "MIB2", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZJV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJV9" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0ZJV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJV9" } ] } ] }, { "uniprot_ac": "A0A8V0ZKK3", "gene_name": "UBE3B", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZKK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKK3" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0ZKK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKK3" } ] } ] }, { "uniprot_ac": "A0A8V0ZKQ3", "gene_name": "RNF25", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZKQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKQ3" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0ZKQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKQ3" } ] } ] }, { "uniprot_ac": "A0A8V0ZL18", "gene_name": "HECTD2", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZL18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZL18" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0ZL18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZL18" } ] } ] }, { "uniprot_ac": "A0A8V0ZM17", "gene_name": "UBR1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZM17", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM17" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0ZM17", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM17" } ] } ] }, { "uniprot_ac": "A0A8V0ZS27", "gene_name": "TRIP12", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZS27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS27" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0ZS27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS27" } ] } ] }, { "uniprot_ac": "A0A8V0ZSA3", "gene_name": "HERC4", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZSA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSA3" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0ZSA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSA3" } ] } ] }, { "uniprot_ac": "A0A8V0ZSH4", "gene_name": "RNF111", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZSH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSH4" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0ZSH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSH4" } ] } ] }, { "uniprot_ac": "A0A8V0ZVX3", "gene_name": "NEDD4", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZVX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVX3" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0ZVX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVX3" } ] } ] }, { "uniprot_ac": "A0A8V0ZW26", "gene_name": "ZNRF1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZW26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZW26" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0ZW26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZW26" } ] } ] }, { "uniprot_ac": "A0A8V0ZZH3", "gene_name": "ITCH", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZZH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZH3" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0ZZH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZH3" } ] } ] }, { "uniprot_ac": "A0A8V1A052", "gene_name": "UBE2E3", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V1A052", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A052" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V1A052", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A052" } ] } ] }, { "uniprot_ac": "A0A8V1A0X2", "gene_name": "UBE3C", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1A0X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0X2" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V1A0X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0X2" } ] } ] }, { "uniprot_ac": "A0A8V1A0Z6", "gene_name": "UBE4A", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1A0Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0Z6" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1A0Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0Z6" } ] } ] }, { "uniprot_ac": "A0A8V1A1I4", "gene_name": "UBE2Z", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V1A1I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1I4" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V1A1I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1I4" } ] } ] }, { "uniprot_ac": "A0A8V1A1N8", "gene_name": "HERC1", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1A1N8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1N8" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V1A1N8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1N8" } ] } ] }, { "uniprot_ac": "A0A8V1A233", "gene_name": "RNF220", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1A233", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A233" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1A233", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A233" } ] } ] }, { "uniprot_ac": "A0A8V1A2W7", "gene_name": "RNF41", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1A2W7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2W7" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1A2W7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2W7" } ] } ] }, { "uniprot_ac": "A0A8V1A4H7", "gene_name": "UBE2L3", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V1A4H7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4H7" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V1A4H7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4H7" } ] } ] }, { "uniprot_ac": "A0A8V1A5P4", "gene_name": "UBE2G2", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V1A5P4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5P4" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V1A5P4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5P4" } ] } ] }, { "uniprot_ac": "A0A8V1A7P9", "gene_name": "DCAF1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A7P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P9" } ] } ] }, { "uniprot_ac": "A0A8V1A7T1", "gene_name": "RNF123", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1A7T1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7T1" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1A7T1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7T1" } ] } ] }, { "uniprot_ac": "A0A8V1A9M0", "gene_name": "RNF34", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1A9M0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9M0" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1A9M0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9M0" } ] } ] }, { "uniprot_ac": "A0A8V1AC19", "gene_name": "UBA7", "activity": [ { "ec_number": "6.2.1.45", "activity": "ATP + ubiquitin + [E1 ubiquitin-activating enzyme]-L-cysteine = AMP + diphosphate + S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V1AC19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC19" } ] }, { "ec_number": "6.2.1.45", "activity": "", "evidence": [ { "id": "A0A8V1AC19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC19" } ] } ] }, { "uniprot_ac": "A0A8V1AC55", "gene_name": "SMURF2", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1AC55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC55" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V1AC55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC55" } ] } ] }, { "uniprot_ac": "A0A8V1ACU3", "gene_name": "UBE2O", "activity": [ { "ec_number": "2.3.2.24", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E1 ubiquitin-activating enzyme]-L-cysteine + N(6)-monoubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1ACU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACU3" } ] }, { "ec_number": "2.3.2.24", "activity": "", "evidence": [ { "id": "A0A8V1ACU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACU3" } ] } ] }, { "uniprot_ac": "A0A8V1AKB8", "gene_name": "TRIM32", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1AKB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKB8" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1AKB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKB8" } ] } ] }, { "uniprot_ac": "A0A8V1AL09", "gene_name": "TRIM37", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1AL09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL09" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1AL09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL09" } ] } ] }, { "uniprot_ac": "A0A8V1ALH0", "gene_name": "RNF213", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1ALH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALH0" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1ALH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALH0" } ] } ] }, { "uniprot_ac": "A0A8V1AML5", "gene_name": "TRIM50", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1AML5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AML5" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1AML5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AML5" } ] } ] }, { "uniprot_ac": "A0A8V1AP69", "gene_name": "TRIM58", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1AP69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP69" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1AP69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP69" } ] } ] }, { "uniprot_ac": "E1BZ35", "gene_name": "RNF182", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1BZ35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BZ35" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "E1BZ35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BZ35" } ] } ] }, { "uniprot_ac": "E1C3Q9", "gene_name": "SIAH2", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1C3Q9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C3Q9" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "E1C3Q9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C3Q9" } ] } ] }, { "uniprot_ac": "E1C656", "gene_name": "HACE1", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1C656", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C656" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "E1C656", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C656" } ] } ] }, { "uniprot_ac": "E1C982", "gene_name": "AREL1", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1C982", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C982" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "E1C982", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C982" } ] } ] }, { "uniprot_ac": "F1NC08", "gene_name": "RNF138", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1NC08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NC08" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "F1NC08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NC08" } ] } ] }, { "uniprot_ac": "F1NL19", "gene_name": "CDC34", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "F1NL19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NL19" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "F1NL19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NL19" } ] } ] }, { "uniprot_ac": "F1NL77", "gene_name": "CBLB", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1NL77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NL77" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "F1NL77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NL77" } ] } ] }, { "uniprot_ac": "F1NRC6", "gene_name": "RLIM", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1NRC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NRC6" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "F1NRC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NRC6" } ] } ] }, { "uniprot_ac": "F1NTZ8", "gene_name": "HECW2", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1NTZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NTZ8" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "F1NTZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NTZ8" } ] } ] }, { "uniprot_ac": "F1NVY8", "gene_name": "LNX1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1NVY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NVY8" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "F1NVY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NVY8" } ] } ] }, { "uniprot_ac": "F1P2G0", "gene_name": "SIAH1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1P2G0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P2G0" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "F1P2G0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P2G0" } ] } ] }, { "uniprot_ac": "Q5ZKX6", "gene_name": "UBE2F", "activity": [ { "ec_number": "2.3.2.34", "activity": "[E1 NEDD8-activating enzyme]-S-[NEDD8 protein]-yl-L-cysteine + [E2 NEDD8-conjugating enzyme]-L-cysteine = [E1 NEDD8-activating enzyme]-L-cysteine + [E2 NEDD8-conjugating enzyme]-S-[NEDD8-protein]-yl-L-cysteine.", "evidence": [ { "id": "Q5ZKX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKX6" } ] }, { "ec_number": "2.3.2.34", "activity": "", "evidence": [ { "id": "Q5ZKX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKX6" } ] } ] }, { "uniprot_ac": "R4GIV8", "gene_name": "UBE2R2", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "R4GIV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GIV8" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "R4GIV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GIV8" } ] } ] }, { "uniprot_ac": "Z4YJC3", "gene_name": "TRIM71", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor 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"Domain_Extent_Annotation", "uniprotkb_annotation": "UBC core", "eco_id": "ECO_0000259", "start_pos": 8, "end_pos": 174, "start_aa": "Ser", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.3.2.23", "ec_name": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "2.3.2.23", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.3.2.23" } ] } ], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1NL56-1", "uniprot_ac": "F1NL56", "uniprot_id": "F1NL56_CHICK", "mass": { "chemical_mass": 43540.0, "monoisotopic_mass": 43540.0 }, "refseq": { "ac": "XP_015150740", "name": "heparan sulfate glucosamine 3-O-sulfotransferase 3A1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015150740" }, "gene_names": [ { "name": "HS3ST3A1", "type": "recommended", "evidence": [ { "id": "F1NL56", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NL56" } ] }, { "name": "HS3ST3A1", "type": "synonym", "evidence": [ { "id": "XP_015150740", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015150740" } ] } ], "protein_names": [ { "name": "Sulfotransferase", "type": "recommended", "evidence": [ { "id": "F1NL56", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NL56/entry#names_and_taxonomy" } ] }, { "name": "2.8.2.-", "type": "synonym", "evidence": [ { "id": "F1NL56", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NL56/entry#names_and_taxonomy" } ] }, { "name": "heparan sulfate glucosamine 3-O-sulfotransferase 3A1", "type": "synonym", "evidence": [ { "id": "XP_015150740", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015150740" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052549.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015150740", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015150740" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NL56", "url": "https://www.uniprot.org/uniprotkb/F1NL56" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "HS3ST3A1", "url": "https://www.uniprot.org/uniprotkb/F1NL56", "locus": { "chromosome": "18", "start_pos": 3450593, "end_pos": 3424319, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029943", "url": "https://www.ensembl.org/id/ENSGALG00010029943" } ] } } ], "crossref": [ { "id": "F1NL56", "url": "https://alphafold.ebi.ac.uk/entry/F1NL56", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000001371", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000001371", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "769490", "url": "https://www.ncbi.nlm.nih.gov/gene/769490", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000863", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000863", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037359", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037359", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:769490", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:769490", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "FYCLVER", "url": "https://omabrowser.org/oma/group/FYCLVER/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1NL56", "url": "https://www.orthodb.org/?gene=F1NL56", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10605", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10605", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10605:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10605:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00685", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00685", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-2022928", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2022928", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_015150740", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015150740", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1NL56", "url": "https://www.uniprot.org/uniprotkb/F1NL56", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NL56-1", "url": "https://www.uniprot.org/uniprotkb/F1NL56-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAVSAAAAPAAEPLPRSIFKKFLVMLCSLLMSLYVFYCLADRCQTLPGPIIAAGAASEEEEGGGGGYLGGSAELPPWQAAAARRKRLLQRLKQRRRRQEAAPGPEVPAGDGGSRAGGSGGGGGGGSAAGTAGTLTLLLGEGSKRLPQAIIIGVKKGGTRALLEFLRVHPDVRAVGAEPHFFDRNYERGLAWYRDLMPRTLEGQITMEKTPSYFVTKEAPARISSMAKGTKLIVVVRDPVTRAISDYTQTLSKKPDIPTFESLTFKNRTTGLIDTSWSAIQIGIYAKHLENWLLYFPIGQILFVSGERLISDPAGELGRVQDFLGLKRIITDKHFYFNKTKGFPCLKKAEGSSKPHCLGKTKGRTHPDIDQEVVQRLRDFYRPFNMKFYQMTGQDFGWD", "length": 398, "header": "tr|F1NL56-1|F1NL56_CHICK Isoform 1 of Sulfotransferase OS=Gallus gallus OX=9031 GN=HS3ST3A1 PE=3 SV=4 CANONICAL=F1NL56-1" }, "isoforms": [ { "isoform_ac": "F1NL56-1", "url": "https://www.uniprot.org/uniprotkb/F1NL56/entry#F1NL56-1", "sequence": { "sequence": "MAVSAAAAPAAEPLPRSIFKKFLVMLCSLLMSLYVFYCLADRCQTLPGPIIAAGAASEEEEGGGGGYLGGSAELPPWQAAAARRKRLLQRLKQRRRRQEAAPGPEVPAGDGGSRAGGSGGGGGGGSAAGTAGTLTLLLGEGSKRLPQAIIIGVKKGGTRALLEFLRVHPDVRAVGAEPHFFDRNYERGLAWYRDLMPRTLEGQITMEKTPSYFVTKEAPARISSMAKGTKLIVVVRDPVTRAISDYTQTLSKKPDIPTFESLTFKNRTTGLIDTSWSAIQIGIYAKHLENWLLYFPIGQILFVSGERLISDPAGELGRVQDFLGLKRIITDKHFYFNKTKGFPCLKKAEGSSKPHCLGKTKGRTHPDIDQEVVQRLRDFYRPFNMKFYQMTGQDFGWD", "length": 398, "header": "tr|F1NL56-1|F1NL56_CHICK Isoform 1 of Sulfotransferase OS=Gallus gallus OX=9031 GN=HS3ST3A1 PE=3 SV=4 CANONICAL=F1NL56-1" }, "locus": { "chromosome": "18", "start_pos": 3447713, "end_pos": 3424319, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010072372.1", "url": "https://www.ensembl.org/id/ENSGALT00010072372.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044839.1", "url": "https://www.ensembl.org/id/ENSGALP00010044839.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "gga:769490", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:769490", "resource": "KEGG Pathway" }, { "id": "R-GGA-2022928", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2022928", "resource": "Reactome", "description": "HS-GAG biosynthesis" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZTA9-1", "protein_name": "Sulfotransferase", "gene_name": "Hs3st3b1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGQRLSGGRSCLDVPGRFLPQPPPPPPPVRRKLALLFAMLCIWLYMFLYSCAGSCTAAPGLLLLGSGSRATHAQPALITAPNETSPKMPFRAPPANSLVAGKDKTVGAGSQEEQSPEAPDSPSPISSFFSGAGSKQLPQAIIIGVKKGGTRALLEFLRVHPDVRAVGAEPHFFDRSYHKGLAWYRDLMPRTLEGQITMEKTPSYFVTREAPARISAMSKDTKLIVVVRDPVTRAISDYTQTLSKRPDIPSFESLTFRNRSAGLIDTSWSAIQIGLYAKHLEPWLRHFPLGQMLFVSGERLVSDPAGELRRVQDFLGLKRIITDKHFYFNQTKGFPCLKKAEGSGKPHCLGKTKGRAHPTIAREVLRQLRDFYRPFNRKFYQMTGRDFGWD", "length": 390 }, "evidence": [ { "id": "F1NL56", "url": "https://omabrowser.org/oma/group/F1NL56/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E1BNJ7-1", "protein_name": "Sulfotransferase", "gene_name": "HS3ST3A1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAPPGPAGAHPTSAEPLSRSVFRKFLLMLCSLLTSLYVFYCLAERCQTLSGPVVGRSGGGEEAGTPGRGVPAGGPGELAAWPVAARRKRLLQVRPRPRRRPPAPRADREEAGEEEPPGLAGSLGGSGAGSSVAETPPGTLALLLDEGSKQLPQAIIIGVKKGGTRALLEFLRVHPDVRAVGAEPHFFDRSYDKGLAWYRDLMPRTLDGQITMEKTPSYFVTREAPARISAMSKDTKLLVVVRDPVTRAVSDYTQTLSKRPDIPSFESLAFRNRSAGLVDRSWSAIQIGLYAEHLERWLRHFPARQMLFVSGERLVRDPAGELGRVQDFLGLKRIISDKHFYFNQTKGFPCLKKAEGSGRPHCLGKTKGRPHPEIDAQVLRQLRDFYRPFNRKFYQMTGHDFGWDG", "length": 405 }, "evidence": [ { "id": "F1NL56", "url": "https://omabrowser.org/oma/group/F1NL56/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q9QZS6-1", "protein_name": "Heparan sulfate glucosamine 3-O-sulfotransferase 3B1", "gene_name": "Hs3st3b1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGQRLSGGRSCLDVPGRFLPQPPPPPPPVRRKLALLFAMLCIWLYMFLYSCAGSCTAAPGLLLLGSGSRATHAQPALVTAPNETSPKMPFRAPPANSLAAGKDKTVGAGSQEEQSPEAPDSPSPISSFFSGAGSKQLPQAIIIGVKKGGTRALLEFLRVHPDVRAVGAEPHFFDRSYHKGLAWYRDLMPRTLKGQITMEKTPSYFVTREAPARISAMSKDTKLIVVVRDPVTRAISDYTQTLSKRPDIPSFESLTFRNRSAGLIDTSWSAIQIGLYAKHLEPWLRHFPLGQMLFVSGERLVSDPAGELRRVQDFLGLKRIITDKHFYFNQTKGFPCLKKAEGSGKPHCLGKTKGRAHPTIAREVLRQLRDFYRPFNRKFYQMTGRDFGWD", "length": 390 }, "evidence": [ { "id": "F1NL56", "url": "https://omabrowser.org/oma/group/F1NL56/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9Y663-1", "protein_name": "Heparan sulfate glucosamine 3-O-sulfotransferase 3A1", "gene_name": "HS3ST3A1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAPPGPASALSTSAEPLSRSIFRKFLLMLCSLLTSLYVFYCLAERCQTLSGPVVGLSGGGEEAGAPGGGVLAGGPRELAVWPAAAQRKRLLQLPQWRRRRPPAPRDDGEEAAWEEESPGLSGGPGGSGAGSTVAEAPPGTLALLLDEGSKQLPQAIIIGVKKGGTRALLEFLRVHPDVRAVGAEPHFFDRSYDKGLAWYRDLMPRTLDGQITMEKTPSYFVTREAPARISAMSKDTKLIVVVRDPVTRAISDYTQTLSKRPDIPTFESLTFKNRTAGLIDTSWSAIQIGIYAKHLEHWLRHFPIRQMLFVSGERLISDPAGELGRVQDFLGLKRIITDKHFYFNKTKGFPCLKKAEGSSRPHCLGKTKGRTHPEIDREVVRRLREFYRPFNLKFYQMTGHDFGWDG", "length": 406 }, "evidence": [ { "id": "F1NL56", "url": "https://omabrowser.org/oma/group/F1NL56/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "F1NL56", "url": "https://www.uniprot.org/uniprotkb/F1NL56" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "glycosaminoglycan biosynthetic process", "id": "GO:0006024", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006024", "evidence": [ { "database": "UniProtKB", "id": "F1NL56", "url": "https://www.uniprot.org/uniprotkb/F1NL56" } ], "pmid": "" }, { "name": "branching involved in ureteric bud morphogenesis", "id": "GO:0001658", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001658", "evidence": [ { "database": "UniProtKB", "id": "F1NL56", "url": "https://www.uniprot.org/uniprotkb/F1NL56" } ], "pmid": "" }, { "name": "heparan sulfate proteoglycan biosynthetic process", "id": "GO:0015012", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015012", "evidence": [ { "database": "UniProtKB", "id": "F1NL56", "url": "https://www.uniprot.org/uniprotkb/F1NL56" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "[heparan sulfate]-glucosamine 3-sulfotransferase activity", "id": "GO:0008467", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008467", "evidence": [ { "database": "UniProtKB", "id": "F1NL56", "url": "https://www.uniprot.org/uniprotkb/F1NL56" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 266, "end_pos": 268, "annotation": "n_glycosylation_sequon" }, { "start_pos": 337, "end_pos": 339, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-GGA-2076611", "name": "HS3ST2-6 sulfate GlcN at C3 in heparan sulfate", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "Golgi lumen, Golgi membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V1AQB3-1", "F1NL56-1", "F1NW51-1", "A0A8V0Z1U8-1", "A0A8V0ZEP2-1", "R4GJI3-1" ], "evidence": [ { "id": "R-GGA-2076611", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2076611" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A8V0Z1U8", "gene_name": "", "activity": [ { "ec_number": "2.8.2.-", "activity": "", "evidence": [ { "id": "A0A8V0Z1U8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1U8" } ] } ] }, { "uniprot_ac": "A0A8V0ZEP2", "gene_name": "HS3ST6", "activity": [ { "ec_number": "2.8.2.-", "activity": "", "evidence": [ { "id": "A0A8V0ZEP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEP2" } ] } ] }, { "uniprot_ac": "A0A8V1AQB3", "gene_name": "HS3ST3B1L", "activity": [ { "ec_number": "2.8.2.-", "activity": "", "evidence": [ { "id": "A0A8V1AQB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AQB3" } ] } ] }, { "uniprot_ac": "F1NL56", "gene_name": "HS3ST3A1", "activity": [ { "ec_number": "2.8.2.-", "activity": "", "evidence": [ { "id": "F1NL56", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NL56" } ] } ] }, { "uniprot_ac": "F1NW51", "gene_name": "HS3ST4", "activity": [ { "ec_number": "2.8.2.-", "activity": "", "evidence": [ { "id": "F1NW51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NW51" } ] } ] }, { "uniprot_ac": "R4GJI3", "gene_name": "HS3ST5", "activity": [ { "ec_number": "2.8.2.-", "activity": "", "evidence": [ { "id": "R4GJI3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GJI3" } ] } ] } ], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1NL56-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 398, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1NL56-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1NL56" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1NL56", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NL56" }, { "id": "PF00685", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00685" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Sulfotransferase", "eco_id": "ECO_0000259", "start_pos": 146, "end_pos": 381, "start_aa": "Pro", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 266, "end_pos": 268 }, { "start_pos": 337, "end_pos": 339 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1NL82-1", "uniprot_ac": "F1NL82", "uniprot_id": "F1NL82_CHICK", "mass": { "chemical_mass": 44250.0, "monoisotopic_mass": 44250.0 }, "refseq": { "ac": "XP_424313", "name": "ethanolamine kinase 2 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_424313" }, "gene_names": [ { "name": "ETNK2", "type": "recommended", "evidence": [ { "id": "F1NL82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NL82" } ] }, { "name": "ETNK2", "type": "synonym", "evidence": [ { "id": "XP_424313", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_424313" } ] } ], "protein_names": [ { "name": "ethanolamine kinase", "type": "recommended", "evidence": [ { "id": "F1NL82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NL82/entry#names_and_taxonomy" } ] }, { "name": "2.7.1.82", "type": "synonym", "evidence": [ { "id": "F1NL82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NL82/entry#names_and_taxonomy" } ] }, { "name": "ethanolamine kinase 2 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_424313", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_424313" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052557.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jan 4, 2016 this sequence version replaced XP_424313.4. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_424313", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_424313" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NL82", "url": "https://www.uniprot.org/uniprotkb/F1NL82" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ETNK2", "url": "https://www.uniprot.org/uniprotkb/F1NL82", "locus": { "chromosome": "26", "start_pos": 1751604, "end_pos": 1759577, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010025748", "url": "https://www.ensembl.org/id/ENSGALG00010025748" } ] } } ], "crossref": [ { "id": "F1NL82", "url": "https://alphafold.ebi.ac.uk/entry/F1NL82", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000000557", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000000557", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd05157", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05157", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "426690", "url": "https://www.ncbi.nlm.nih.gov/gene/426690", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011009", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011009", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PMIWTKT", "url": "https://omabrowser.org/oma/group/PMIWTKT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1NL82", "url": "https://www.orthodb.org/?gene=F1NL82", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22603", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22603", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22603:SF94", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22603:SF94", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01633", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01633", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-1483213", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1483213", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_424313", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_424313", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1NL82", "url": "https://www.uniprot.org/uniprotkb/F1NL82", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NL82-1", "url": "https://www.uniprot.org/uniprotkb/F1NL82-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGRGSGRSEPGMAVPPGRCPDCWETERGGGGGGSRGVPGVLQLGVLVDEGDVLPGALRLMRELRPSWEPARVKTKLFTDGITNKLVACYTDEDMADAVLVRVYGRKTELFVDRETELRNFQVLRAHGCAPDLYCAFQNGLCYEFLPGIALGPDHVRDPRIFRLVAQEMARVHAIHANGSLPKPILWQKLHKYLALVKMDLSPKVPNPSLHQDVPSLEMLEHELAWMKDTLSQLGSPVVLCHNDLLCKNIIYNRAQEHVRFIDYEYTGYNYQAFDIGNHFNEFAGVKEVDYRLYPSKETQLQWLRSYLQAYKQLTQGGQGGTGVTVSEKELEALYVQVNKFSLASHFLWACWGLIQDKYSTIDFNFLRYAKLRFRQYFKMKPVVTALQISK", "length": 390, "header": "tr|F1NL82-1|F1NL82_CHICK Isoform 1 of ethanolamine kinase OS=Gallus gallus OX=9031 GN=ETNK2 PE=1 SV=3 CANONICAL=F1NL82-1" }, "isoforms": [ { "isoform_ac": "F1NL82-1", "url": "https://www.uniprot.org/uniprotkb/F1NL82/entry#F1NL82-1", "sequence": { "sequence": "MGRGSGRSEPGMAVPPGRCPDCWETERGGGGGGSRGVPGVLQLGVLVDEGDVLPGALRLMRELRPSWEPARVKTKLFTDGITNKLVACYTDEDMADAVLVRVYGRKTELFVDRETELRNFQVLRAHGCAPDLYCAFQNGLCYEFLPGIALGPDHVRDPRIFRLVAQEMARVHAIHANGSLPKPILWQKLHKYLALVKMDLSPKVPNPSLHQDVPSLEMLEHELAWMKDTLSQLGSPVVLCHNDLLCKNIIYNRAQEHVRFIDYEYTGYNYQAFDIGNHFNEFAGVKEVDYRLYPSKETQLQWLRSYLQAYKQLTQGGQGGTGVTVSEKELEALYVQVNKFSLASHFLWACWGLIQDKYSTIDFNFLRYAKLRFRQYFKMKPVVTALQISK", "length": 390, "header": "tr|F1NL82-1|F1NL82_CHICK Isoform 1 of ethanolamine kinase OS=Gallus gallus OX=9031 GN=ETNK2 PE=1 SV=3 CANONICAL=F1NL82-1" }, "locus": { "chromosome": "26", "start_pos": 1759545, "end_pos": 1752755, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010062832.1", "url": "https://www.ensembl.org/id/ENSGALT00010062832.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038824.1", "url": "https://www.ensembl.org/id/ENSGALP00010038824.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "R-GGA-1483213", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1483213", "resource": "Reactome", "description": "Synthesis of PE" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A5G2Q783-1", "protein_name": "ethanolamine kinase", "gene_name": "ETNK2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGHGGEGGGRRGLPGAAGPPRAAAVPCFGISVDHNDILPGALRLIRELRPHWKPEQVRTKRFTDGITNKLVACYVDEDMRDCVLVRVYGERTELLVDRENEVRNFQLLRAHGCAPKLYCTFQNGLCYEYMQGMALGPEHIREPRLFRLIALEMAKIHTIHANGSLPKPILWHKIHNYFTLVKNEINPSLSADVPKVEVLEQELAWLKEHLSQLDSPVVFCHNDLLCKNIIYDSTKGHVRFIDYEYAGYNYQAFDIGNHFNEFAGVNEVDYCLYPSRETQLQWLRYYLQAQKGMAVTPREVERLYVQVNKFALASHFLWALWALIQSQFSTIDFDFLRYAVIRFNQYFKVKPQVSALEMPK", "length": 360 }, "evidence": [ { "id": "F1NL82", "url": "https://omabrowser.org/oma/group/F1NL82/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A7MCT6-1", "protein_name": "Ethanolamine kinase 2", "gene_name": "Etnk2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAVPPSAPVPCSPFYLRRQEPCPQCSWSMEEKAVASAGCWEPPGPPRAAVPCFSVTVEQDDILPGALRLIRELRPHWKPEQVRTKRFKDGITNKLLACYVEEDMRDCVLVRVYGERTELLVDRENEVRNFQLLRAHGCAPKLYCTFQNGLCYEYVQGVALGPEHIREPQLFRLIALEMAKIHTIHANGSLPKPTLWHKMHRYFTLVKDEISPSLSADVPKVEVLEQELAWLKEHLSQLDSPVVFCHNDLLCKNIIYDSDKGRVCFIDYEYAGYNYQAFDIGNHFNEFAGVNVVDYSRYPARETQVQWLRYYLEAQKGTAASPREVERLYAQVNKFALASHFFWALWALIQNQYSTISFDFLRYAVIRFNQYFKVKPQVSALEMPK", "length": 385 }, "evidence": [ { "id": "F1NL82", "url": "https://omabrowser.org/oma/group/F1NL82/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F1MRD9-1", "protein_name": "ethanolamine kinase", "gene_name": "ETNK2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MEAAAGAGRGAPPGPPRAAAVPCFGISVDQDDILPGALRLIRELRPRWKPERVRTKRFTDGITNKLVACYVEEDMRDCVLVRVYGERTELLVDRESEVRNFQLLRAHGCAPKLYCTFQNGLCYEYMRGVALGPEHIREPRLFRLIALEMAKIHTIHANGSLPKPTLWHKIHNYFALVKNEINPSLSADVPEVGVLERELVWLKEHLPPLDSPVVFCHNDLLCKNIIYDSSKGHVRFIDYEYAGYNYQAFDIGNHFNEFAGVNEVDYSRYPARETQLLWLRYYLQAQNGTAVTPREVERLYVQVNKFALASHFLWALWALIQNQFSTIDFDFLRYAVIRFNQYFKVKPQVAALEMPK", "length": 356 }, "evidence": [ { "id": "F1NL82", "url": "https://omabrowser.org/oma/group/F1NL82/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "O81024-1", "protein_name": "Probable ethanolamine kinase", "gene_name": "EMB1187", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MGAAKNIWALANAEDAANDAEQIPYSSFVVDTSLPLPLMIPRIIELCKDLFKNWGELDDSLFSVERVSGGITNLLLKVSVKEDTNKEVSVTVRLYGPNTEYVINREREILAIKYLSAAGFGAKLLGGFGNGMVQSFINARTLEPSDMREPKIAAQIARELGKFHKVDIPGSKEPQLWVDILKFYEKASTLTFEEPDKQKLFETISFEELHKEIIELREFTGLLNAPVVFAHNDLLSGNFMLNDEEEKLYLIDFEYGSYNYRGFDIGNHFNEYAGYDCDYSLYPSKEEQYHFIKHYLQPDKPDEVSIAEVESVFVETDAYKLASHLYWAIWAIIQARMSPIEFEYLGYFFLRYNEYKKQKPLTFSLVTSHLSASL", "length": 374 }, "evidence": [ { "id": "F1NL82", "url": "https://omabrowser.org/oma/group/F1NL82/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9NVF9-1", "protein_name": "Ethanolamine kinase 2", "gene_name": "ETNK2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAVPPSAPQPRASFHLRRHTPCPQCSWGMEEKAAASASCREPPGPPRAAAVAYFGISVDPDDILPGALRLIQELRPHWKPEQVRTKRFTDGITNKLVACYVEEDMQDCVLVRVYGERTELLVDRENEVRNFQLLRAHSCAPKLYCTFQNGLCYEYMQGVALEPEHIREPRLFRLIALEMAKIHTIHANGSLPKPILWHKMHNYFTLVKNEINPSLSADVPKVEVLERELAWLKEHLSQLESPVVFCHNDLLCKNIIYDSIKGHVRFIDYEYAGYNYQAFDIGNHFNEFAGVNEVDYCLYPARETQLQWLHYYLQAQKGMAVTPREVQRLYVQVNKFALASHFFWALWALIQNQYSTIDFDFLRYAVIRFNQYFKVKPQASALEMPK", "length": 386 }, "evidence": [ { "id": "F1NL82", "url": "https://omabrowser.org/oma/group/F1NL82/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1NL82", "url": "https://www.uniprot.org/uniprotkb/F1NL82" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "phosphatidylethanolamine biosynthetic process", "id": "GO:0006646", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006646", "evidence": [ { "database": "UniProtKB", "id": "F1NL82", "url": "https://www.uniprot.org/uniprotkb/F1NL82" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "ethanolamine kinase activity", "id": "GO:0004305", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004305", "evidence": [ { "database": "UniProtKB", "id": "F1NL82", "url": "https://www.uniprot.org/uniprotkb/F1NL82" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 177, "end_pos": 179, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-GGA-1483222", "name": "ETA is phosphorylated to PETA by CHK/ETNK", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [ "R-ALL-1498751" ], "output_participant_list": [], "enzyme_list": [ "F1NL82-1", "F1NMC4-1", "A0A1D5P2G3-1" ], "evidence": [ { "id": "R-GGA-1483222", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1483222" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-1498751", "participant_name": "ETA [cytosol]", "crossref": [ { "id": "57603", "database": "ChEBI", "url": "" }, { "id": "ZINC000008214617", "database": "ZINC", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A0A1D5P2G3", "gene_name": "CHKA", "activity": [ { "ec_number": "2.7.1.32", "activity": "choline + ATP = phosphocholine + ADP + H(+).", "evidence": [ { "id": "A0A1D5P2G3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P2G3" } ] }, { "ec_number": "2.7.1.82", "activity": "ethanolamine + ATP = phosphoethanolamine + ADP + H(+).", "evidence": [ { "id": "A0A1D5P2G3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P2G3" } ] }, { "ec_number": "2.7.1.82", "activity": "", "evidence": [ { "id": "A0A1D5P2G3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P2G3" } ] }, { "ec_number": "2.7.1.32", "activity": "", "evidence": [ { "id": "A0A1D5P2G3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P2G3" } ] } ] }, { "uniprot_ac": "F1NL82", "gene_name": "ETNK2", "activity": [ { "ec_number": "2.7.1.82", "activity": "ethanolamine + ATP = phosphoethanolamine + ADP + H(+).", "evidence": [ { "id": "F1NL82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NL82" } ] }, { "ec_number": "2.7.1.82", "activity": "", "evidence": [ { "id": "F1NL82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NL82" } ] } ] }, { "uniprot_ac": "F1NMC4", "gene_name": "ETNK1", "activity": [ { "ec_number": "2.7.1.82", "activity": "ethanolamine + ATP = phosphoethanolamine + ADP + H(+).", "evidence": [ { "id": "F1NMC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NMC4" } ] }, { "ec_number": "2.7.1.82", "activity": "", "evidence": [ { "id": "F1NMC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NMC4" } ] } ] } ], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1NL82-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 390, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1NL82-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1NL82" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.7.1.82", "ec_name": "ethanolamine + ATP = phosphoethanolamine + ADP + H(+).", "evidence": [ { "id": "2.7.1.82", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.82" }, { "id": "2.7.1.82", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.7.1.82" } ] } ], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 177, "end_pos": 179 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": 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0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1NLG8-1", "uniprot_ac": "F1NLG8", "uniprot_id": "F1NLG8_CHICK", "mass": { "chemical_mass": 33594.0, "monoisotopic_mass": 33594.0 }, "refseq": { "ac": "XP_003642240", "name": "translation initiation factor eIF-2B subunit alpha", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003642240" }, "gene_names": [ { "name": "EIF2B1", "type": "recommended", "evidence": [ { "id": "F1NLG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NLG8" } ] }, { "name": "EIF2B1", "type": "synonym", "evidence": [ { "id": "XP_003642240", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003642240" } ] } ], "protein_names": [ { "name": "Translation initiation factor eIF2B subunit alpha", "type": "recommended", "evidence": [ { "id": "F1NLG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NLG8/entry#names_and_taxonomy" } ] }, { "name": "eIF2B GDP-GTP exchange factor subunit alpha", "type": "synonym", "evidence": [ { "id": "F1NLG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NLG8/entry#names_and_taxonomy" } ] }, { "name": "translation initiation factor eIF-2B subunit alpha", "type": "synonym", "evidence": [ { "id": "XP_003642240", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003642240" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052546.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003642240", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003642240" } ] }, { "annotation": "Acts as a component of the translation initiation factor 2B (eIF2B) complex, which catalyzes the exchange of GDP for GTP on eukaryotic initiation factor 2 (eIF2) gamma subunit. Its guanine nucleotide exchange factor activity is repressed when bound to eIF2 complex phosphorylated on the alpha subunit, thereby limiting the amount of methionyl-initiator methionine tRNA available to the ribosome and consequently global translation is repressed.", "evidence": [ { "database": "UniProtKB", "id": "F1NLG8", "url": "https://www.uniprot.org/uniprotkb/F1NLG8#function" }, { "database": "UniProtKB", "id": "ARBA00043898", "url": "https://www.uniprot.org/uniprotkb/ARBA00043898#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NLG8", "url": "https://www.uniprot.org/uniprotkb/F1NLG8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "EIF2B1", "url": "https://www.uniprot.org/uniprotkb/F1NLG8", "locus": { "chromosome": "15", "start_pos": 4962751, "end_pos": 4959389, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010024701", "url": "https://www.ensembl.org/id/ENSGALG00010024701" } ] } } ], "crossref": [ { "id": "F1NLG8", "url": "https://alphafold.ebi.ac.uk/entry/F1NLG8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000003259", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000003259", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100857736", "url": "https://www.ncbi.nlm.nih.gov/gene/100857736", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000649", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000649", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037171", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037171", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042528", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042528", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042529", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042529", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051501", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051501", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:100857736", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100857736", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "GDWESCK", "url": "https://omabrowser.org/oma/group/GDWESCK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1NLG8", "url": "https://www.orthodb.org/?gene=F1NLG8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45860", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45860", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45860:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45860:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01008", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01008", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-72731", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-72731", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_003642240", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003642240", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1NLG8", "url": "https://www.uniprot.org/uniprotkb/F1NLG8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NLG8-1", "url": "https://www.uniprot.org/uniprotkb/F1NLG8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSTDDLIETFRAQLRDDPDVASAVAAIRALLGFLRQDRGETIQGLRSSLRDAIDTLSRVDSSVAVNSGGELFLRFISLTSLEYSDYSKCKEIMIERGEIFLRKVSLSRNKIAKLCHPFIRDGARILTHAYSRVVLRVLEAAVESKKRFSVYVTESQPDQAGQKMAKALRKLNIPVTVILDAAVGYIMEKVDLVLVGAEGVVESGGIINKIGTNQIAVCAKAQNKPFYVVAESFKFVRLFPLNQQDVPDKFKYKADTLKTSQNLTEEHPWIDYTSPSLITLLFTDLGVLTPSAVSDELIKLYL", "length": 302, "header": "tr|F1NLG8-1|F1NLG8_CHICK Isoform 1 of Translation initiation factor eIF2B subunit alpha OS=Gallus gallus OX=9031 GN=EIF2B1 PE=1 SV=3 CANONICAL=F1NLG8-1" }, "isoforms": [ { "isoform_ac": "F1NLG8-1", "url": "https://www.uniprot.org/uniprotkb/F1NLG8/entry#F1NLG8-1", "sequence": { "sequence": "MSTDDLIETFRAQLRDDPDVASAVAAIRALLGFLRQDRGETIQGLRSSLRDAIDTLSRVDSSVAVNSGGELFLRFISLTSLEYSDYSKCKEIMIERGEIFLRKVSLSRNKIAKLCHPFIRDGARILTHAYSRVVLRVLEAAVESKKRFSVYVTESQPDQAGQKMAKALRKLNIPVTVILDAAVGYIMEKVDLVLVGAEGVVESGGIINKIGTNQIAVCAKAQNKPFYVVAESFKFVRLFPLNQQDVPDKFKYKADTLKTSQNLTEEHPWIDYTSPSLITLLFTDLGVLTPSAVSDELIKLYL", "length": 302, "header": "tr|F1NLG8-1|F1NLG8_CHICK Isoform 1 of Translation initiation factor eIF2B subunit alpha OS=Gallus gallus OX=9031 GN=EIF2B1 PE=1 SV=3 CANONICAL=F1NLG8-1" }, "locus": { "chromosome": "15", "start_pos": 4962746, "end_pos": 4959547, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010060297.1", "url": "https://www.ensembl.org/id/ENSGALT00010060297.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010037055.1", "url": "https://www.ensembl.org/id/ENSGALP00010037055.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:100857736", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100857736", "resource": "KEGG Pathway" }, { "id": "R-GGA-72731", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-72731", "resource": "Reactome", "description": "Recycling of eIF2:GDP" } ], "orthologs": [ { "uniprot_canonical_ac": "P14741-1", "protein_name": "Translation initiation factor eIF2B subunit alpha", "gene_name": "GCN3", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSEFNITETYLRFLEEDTEMTMPIAAIEALVTLLRIKTPETAAEMINTIKSSTEELIKSIPNSVSLRAGCDIFMRFVLRNLHLYGDWENCKQHLIENGQLFVSRAKKSRNKIAEIGVDFIADDDIILVHGYSRAVFSLLNHAANKFIRFRCVVTESRPSKQGNQLYTLLEQKGIPVTLIVDSAVGAVIDKVDKVFVGAEGVAESGGIINLVGTYSVGVLAHNARKPFYVVTESHKFVRMFPLSSDDLPMAGPPLDFTRRTDDLEDALRGPTIDYTAQEYITALITDLGVLTPSAVSEELIKMWYD", "length": 305 }, "evidence": [ { "id": "F1NLG8", "url": "https://omabrowser.org/oma/group/F1NLG8/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q0IIF2-1", "protein_name": "Translation initiation factor eIF2B subunit alpha", "gene_name": "EIF2B1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MDNTELIEYFKSQIKEDPDMASAVAAIRTLLEYLRRDTGETIQGLRANLTSAIETLCGVDSSVAVSSGGELFLRFISLTSLEYSDYSKCKKIMIERGEIFLRRISLSRNKIADLCHTFIKDGARILTHAYSRVVLRVLEAAVAAKKRFSVYITESQPDLSGKKMAKALCHLNVPVTVVLDAAVGYIMEKVDLVIVGAEGVVENGGIINKIGTNQMAVCAKAQNKPFYVVAESFKFVRLFPLNQQDVPDKFKYKADTLKSVQTGQDLREEHPWVDYTSPSLITLLFTDLGVLTPSAVSDELIKLYL", "length": 305 }, "evidence": [ { "id": "F1NLG8", "url": "https://omabrowser.org/oma/group/F1NLG8/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q14232-1", "protein_name": "Translation initiation factor eIF2B subunit alpha", "gene_name": "EIF2B1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDDKELIEYFKSQMKEDPDMASAVAAIRTLLEFLKRDKGETIQGLRANLTSAIETLCGVDSSVAVSSGGELFLRFISLASLEYSDYSKCKKIMIERGELFLRRISLSRNKIADLCHTFIKDGATILTHAYSRVVLRVLEAAVAAKKRFSVYVTESQPDLSGKKMAKALCHLNVPVTVVLDAAVGYIMEKADLVIVGAEGVVENGGIINKIGTNQMAVCAKAQNKPFYVVAESFKFVRLFPLNQQDVPDKFKYKADTLKVAQTGQDLKEEHPWVDYTAPSLITLLFTDLGVLTPSAVSDELIKLYL", "length": 305 }, "evidence": [ { "id": "F1NLG8", "url": "https://omabrowser.org/oma/group/F1NLG8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q54I81-1", "protein_name": "Translation initiation factor eIF2B subunit alpha", "gene_name": "eif2b1", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MTGGLNKDFDWVVAKFEEMIKRETEVSIAIPTIRILIDVIRKSNSTTVVGLQKELEDAVKQLKSCPYNQSISLSSVCDSFIRFVTKRTELDFPNFDTCKSNLVERGEQLSNKSSMSRTKISQLADKFIRDGVTILVHGFSRVVLGLLLHAAFQGKRFSVIVTESRPDSSGYKTAARLQAANIPVKLIMDGGVSRIIDKVDYVLVGAEAIVENGGIVNKIGTYQISIVAKAFKKPFYVAAESFKFTRSYPLNQSDIENLKNDHISEPFKACRSCSSCENPEQLTIDSPTLDYTPPSYITLLFTELGVLTPSAVSDELIKLYC", "length": 321 }, "evidence": [ { "id": "F1NLG8", "url": "https://omabrowser.org/oma/group/F1NLG8/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q64270-1", "protein_name": "Translation initiation factor eIF2B subunit alpha", "gene_name": "Eif2b1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEDGELIKYFKSQMKGDPNMASAVAAIQTLLEFLKRDKGETIQGLRAHLTKAIETLCAVDSSVAVSSGGELFLRFISLTSLEYSDYSKCKKIMIERGELFLSRISLSRTKIASLCHAFIKDGARILTHAYSRVVLRVLEEAVAAKKRFSVYITESQPDLSGKKMAKALCHLNVPVTVVLDAAVGYIMEKVDLVIVGAEGVVENGGIINKIGTNQMAVCAKAQNKPFYVVAESFKFVRLFPLNQQDVPDKFKYKADTLKSVQAGQDLKEEHPWVDYTSPSLITLLFTDLGVLTPSAVSDELIKLYL", "length": 305 }, "evidence": [ { "id": "F1NLG8", "url": "https://omabrowser.org/oma/group/F1NLG8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q99LC8-1", "protein_name": "Translation initiation factor eIF2B subunit alpha", "gene_name": "Eif2b1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEDGELIEYFKSQMKGDPKMASAVAAIQTLLEFLKRDKGETLQGLRANLTYAIKTLCGVDSSVAVSSGGELFLRFISLTSLEYSDYSKCKKIMIERGELFLRRISLSRNKIANLCHTFIKDGARILTHAYSRVVLRVLEEAVAAKKRFSVYITESQPDLSGKKMAKALSHLNVPVTVVLDAAVGYIMEKADLVIVGAEGVVENGGIINKIGTNQMAVCAKAQNKPFYVVAESFKFVRLFPLNQEDVPDKFKYKADTLKSVQTGQDLKEEHPWVDYTSPSLITLLFTDLGVLTPSAVSDELIKLYL", "length": 305 }, "evidence": [ { "id": "F1NLG8", "url": "https://omabrowser.org/oma/group/F1NLG8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VAD4-1", "protein_name": "Translation initiation factor eIF2B subunit alpha", "gene_name": "eIF2Balpha", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MPQITENGQDFDVVKYFLQLLDEDKDLSSGIAAIRTLLMILEKKQFGTIHILHTTMREAVAAMRNTDLSIAAIVSAGELFCRFITLSLDDKHMEECRQIMLNRGKIFLTKLLNSRQVIAQQAQRFITDGCRILTHSRSRVVLKALITASQNKKSFHVYVTQGGTGNSGEEMVKDLHAAGIDCTLILDSATGYVMESVDFVLVGAEAVVESGGIINRIGTYTMGLCAREMKKPFYVLAESFKFSRLYPLNQRDLPNEYKYSRKHLNDVSKVHPLVDYTPPVYITLLFTDLGRLTPSAVSDELIKLYM", "length": 306 }, "evidence": [ { "id": "F1NLG8", "url": "https://omabrowser.org/oma/group/F1NLG8/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "cytoplasmic translational initiation", "id": "GO:0002183", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002183", "evidence": [ { "database": "UniProtKB", "id": "F1NLG8", "url": "https://www.uniprot.org/uniprotkb/F1NLG8" } ], "pmid": "" }, { "name": "T cell receptor signaling pathway", "id": "GO:0050852", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050852", "evidence": [ { "database": "UniProtKB", "id": "F1NLG8", "url": "https://www.uniprot.org/uniprotkb/F1NLG8" } ], "pmid": "" }, { "name": "translational initiation", "id": "GO:0006413", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006413", "evidence": [ { "database": "UniProtKB", "id": "F1NLG8", "url": "https://www.uniprot.org/uniprotkb/F1NLG8" } ], "pmid": "" }, { "name": "oligodendrocyte development", "id": "GO:0014003", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0014003", "evidence": [ { "database": "UniProtKB", "id": "F1NLG8", "url": "https://www.uniprot.org/uniprotkb/F1NLG8" } ], "pmid": "" }, { "name": "positive regulation of translational initiation", "id": "GO:0045948", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045948", "evidence": [ { "database": "UniProtKB", "id": "F1NLG8", "url": "https://www.uniprot.org/uniprotkb/F1NLG8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F1NLG8", "url": "https://www.uniprot.org/uniprotkb/F1NLG8" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F1NLG8", "url": "https://www.uniprot.org/uniprotkb/F1NLG8" } ], "pmid": "" }, { "name": "eukaryotic translation initiation factor 2B complex", "id": "GO:0005851", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005851", "evidence": [ { "database": "UniProtKB", "id": "F1NLG8", "url": "https://www.uniprot.org/uniprotkb/F1NLG8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "F1NLG8", "url": "https://www.uniprot.org/uniprotkb/F1NLG8" } ], "pmid": "" }, { "name": "guanyl-nucleotide exchange factor activity", "id": "GO:0005085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005085", "evidence": [ { "database": "UniProtKB", "id": "F1NLG8", "url": "https://www.uniprot.org/uniprotkb/F1NLG8" } ], "pmid": "" }, { "name": "translation initiation factor activity", "id": "GO:0003743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003743", "evidence": [ { "database": "UniProtKB", "id": "F1NLG8", "url": "https://www.uniprot.org/uniprotkb/F1NLG8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 262, "end_pos": 264, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1NLG8-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 302, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1NLG8-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1NLG8" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 262, "end_pos": 264 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1NLG9-1", "uniprot_ac": "F1NLG9", "uniprot_id": "F1NLG9_CHICK", "mass": { "chemical_mass": 42361.0, "monoisotopic_mass": 42361.0 }, "refseq": { "ac": "NP_001264755", "name": "phosphatidylcholine:ceramide cholinephosphotransferase 2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264755" }, "gene_names": [ { "name": "SGMS2", "type": "recommended", "evidence": [ { "id": "F1NLG9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NLG9" } ] }, { "name": "SGMS2", "type": "synonym", "evidence": [ { "id": "NP_001264755", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264755" } ] } ], "protein_names": [ { "name": "Sphingomyelin synthase 2", "type": "synonym", "evidence": [ { "id": "F1NLG9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NLG9/entry#names_and_taxonomy" } ] }, { "name": "phosphatidylcholine:ceramide cholinephosphotransferase 2", "type": "synonym", "evidence": [ { "id": "NP_001264755", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264755" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: BX934875.2, SRR13267648.17413.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA103992290, SAMEA103992323 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000073.1. On Apr 21, 2013 this sequence version replaced XP_420492.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001264755", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264755" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NLG9", "url": "https://www.uniprot.org/uniprotkb/F1NLG9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SGMS2", "url": "https://www.uniprot.org/uniprotkb/F1NLG9", "locus": { "chromosome": "4", "start_pos": 37554013, "end_pos": 37584664, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010005670", "url": "https://www.ensembl.org/id/ENSGALG00010005670" } ] } } ], "crossref": [ { "id": "F1NLG9", "url": "https://alphafold.ebi.ac.uk/entry/F1NLG9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000010535", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000010535", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd01610", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01610", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "422529", "url": "https://www.ncbi.nlm.nih.gov/gene/422529", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR025749", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025749", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045221", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045221", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:422529", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422529", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "SKFPLEW", "url": "https://omabrowser.org/oma/group/SKFPLEW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1NLG9", "url": "https://www.orthodb.org/?gene=F1NLG9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21290", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21290", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21290:SF24", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21290:SF24", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF14360", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14360", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-1660661", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1660661", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001264755", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264755", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "36079", "url": "https://www.rhea-db.org/rhea/36079", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "F1NLG9", "url": "https://www.uniprot.org/uniprotkb/F1NLG9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NLG9-1", "url": "https://www.uniprot.org/uniprotkb/F1NLG9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNTIETAKLEDHMEGQNNDTANGYTRPTLSVSEENKNGNNKPKGLSNGLRKTAKKYPDYIQIAMPAESRNKFPLEWWKTGIAFVYALFNLILTTVMITVVHERVPPKERSPPLPDKFFDYIDRVTWAFSVSEINGMILVGLWIFQWLFLRYKSIVGRRFFFIIGTLYLYRCITMYVTTLPVPGMHFQCAPKLNGDSQAKVQRILRLISGGGLSITGSHILCGDFLFSGHTVVLTLIYLFIKEYSPRHFWWYHLICWLMSAAGIICILVAHEHYTVDVIIAYYITTRLFWWYHSMANEKTLKVSSQTNFLSRAWWYPIFYFFEKNVQGSVPCSFSWPISWPPSCFKSSCKKYSRVQKTGEDNEKST", "length": 365, "header": "tr|F1NLG9-1|F1NLG9_CHICK Isoform 1 of Sphingomyelin synthase 2 OS=Gallus gallus OX=9031 GN=SGMS2 PE=3 SV=2 CANONICAL=F1NLG9-1" }, "isoforms": [ { "isoform_ac": "F1NLG9-1", "url": "https://www.uniprot.org/uniprotkb/F1NLG9/entry#F1NLG9-1", "sequence": { "sequence": "MNTIETAKLEDHMEGQNNDTANGYTRPTLSVSEENKNGNNKPKGLSNGLRKTAKKYPDYIQIAMPAESRNKFPLEWWKTGIAFVYALFNLILTTVMITVVHERVPPKERSPPLPDKFFDYIDRVTWAFSVSEINGMILVGLWIFQWLFLRYKSIVGRRFFFIIGTLYLYRCITMYVTTLPVPGMHFQCAPKLNGDSQAKVQRILRLISGGGLSITGSHILCGDFLFSGHTVVLTLIYLFIKEYSPRHFWWYHLICWLMSAAGIICILVAHEHYTVDVIIAYYITTRLFWWYHSMANEKTLKVSSQTNFLSRAWWYPIFYFFEKNVQGSVPCSFSWPISWPPSCFKSSCKKYSRVQKTGEDNEKST", "length": 365, "header": "tr|F1NLG9-1|F1NLG9_CHICK Isoform 1 of Sphingomyelin synthase 2 OS=Gallus gallus OX=9031 GN=SGMS2 PE=3 SV=2 CANONICAL=F1NLG9-1" }, "locus": { "chromosome": "4", "start_pos": 37561499, "end_pos": 37555699, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010013547.1", "url": "https://www.ensembl.org/id/ENSGALT00010013547.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010008036.1", "url": "https://www.ensembl.org/id/ENSGALP00010008036.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:422529", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422529", "resource": "KEGG Pathway" }, { "id": "R-GGA-1660661", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1660661", "resource": "Reactome", "description": "Sphingolipid de novo biosynthesis" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8M1NT99-1", "protein_name": "2.7.8.27", "gene_name": "sgms2a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MASSDHQGNKEPTNTSRTDGAPSTGATCPVHSAEDAKRNGLRKGLVRHRDYVKISVPEGKGNRLPSEWWKTFIALFYAALNLVLTTVMITVVHERVPPKEESPPLPDKFFDYIDRVQWAFTVTEVNGMVLVSIWGIQLLFHRYKAIVARRYFFLLGTLYMYRCITMYVTTLPVPGMHMVCAPKLHGDSEAKLQRVLQLLSGGGLSINGSHLLCGDFLYSGHTVILTLTYLFLKEYSPRSFWWYHLLCWLTAAVGVVCILVAHEHYSVDVVVAYFITTRLFYWYHTMANLQTLKCSPNNYLTHTWWNPVFNLFERNVQTHVPCSFCWPITWPPACLKNPCKKYSMVQSGREE", "length": 351 }, "evidence": [ { "id": "F1NLG9", "url": "https://omabrowser.org/oma/group/F1NLG9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "E1BNX6-1", "protein_name": "Sphingomyelin synthase 2", "gene_name": "SGMS2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MDIIETAKLEEHMENQTNDPANTYTRPPEPVEEENKNGNSKPKSLSNGLRKSTKKYPDYIQIAMPTEARNKFPLEWWKTGIAFVYALFNLVLTTVMITVVHERVPPKELSPPLPDKFFDYIDRVKWAFSVSEINGIILVGLWITQWLFLRYKSIVGRRFFFIIGTLYLYRCITMYVTTLPVPGMHFQCAPKLNGDSQAKVQRILRLISGGGLSITGSHILCGDFLFSGHTVVLTLTYLFIKEYSPRHFWWYHLICWLLSAAGIICILVAHEHYTVDVIVAYYITTRLFWWYHSMANEKNLKVSSQTNFLSRAWWFPIFYFFEKNVQGSIPCCFSWPLSWPPGCFKSSCKKYSRVQKIGEDNEKST", "length": 365 }, "evidence": [ { "id": "F1NLG9", "url": "https://omabrowser.org/oma/group/F1NLG9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1S122-1", "protein_name": "Sphingomyelin synthase 2", "gene_name": "SGMS2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDIIETAKLEEHMENQTSEPANTYARPAEPIEEENKNGNGKPKSLSNGLRKGTKKYPDYIQIAMPTDSRNKFPLEWWKTGIAFVYALFNLVLTTVMITVVHERVPPKELSPPLPDKFFDYIDRVKWAFSVSEINGIILVGLWITQWLFLRYKSIVGRRFFFIIGTLYLYRCITMYVTTLPVPGMHFQCAPKLNGDSQAKVQRILRLISGGGLSITGSHILCGDFLFSGHTVVLTLTYLFIKEYSPRHFWWYHLICWLLSAAGIICILVAHEHYTVDVIVAYYITTRLFWWYHSMANEKNLKVSSQTNFLSRAWWFPIFYFFEKNVQGSIPCCFSWPLSWPPGCFKSSCKKYSRVQKIGEDNEKST", "length": 365 }, "evidence": [ { "id": "F1NLG9", "url": "https://omabrowser.org/oma/group/F1NLG9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3I338-1", "protein_name": "Phosphatidylcholine:ceramide cholinephosphotransferase 2 isoform X1", "gene_name": "Sgms2", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MDIIETAKLEGHLENQTNDSTNTYTGPADTVEEGNKNGNGKPKSLSNGLRKGAKKYPDYIQISMPTDSRNKFPLEWWKTGIAFVYALFNLVLTTVMITVVHERVPPKELSPPLPDKFFDYVDRVKWAFSVSEINGIVLVGLWITQWLFLRYKSIVGRRFFFIIGTLYLYRCITMYVTTLPVPGMHFQCAPKLNGDSQAKIQRILRLISGGGLSITGSHILCGDFLFSGHTVVLTLTYLFIKEYSPRHFWWYHLVCWLLSAAGIICILVAHEHYTVDVIIAYYITTRLFWWYHSMANEKNLKVSSQTNFLSRAWWFPIFYFFEKNVQGSIPCCFSWPLSWPPGCFKSSCKKYSRVQKIGEDNEKST", "length": 365 }, "evidence": [ { "id": "F1NLG9", "url": "https://omabrowser.org/oma/group/F1NLG9/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q4JM44-1", "protein_name": "Phosphatidylcholine:ceramide cholinephosphotransferase 2", "gene_name": "Sgms2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDIIETAKLEGHLESQTNNSTNTYTSPTEAVEEEDKNGKGKPKTLSNGLRKGAKKYPDYIQISMPNDSRNKLPLEWWKTGIAFVYALFNLILTTVMITVVHERVPPKELSPPLPDKFFDYVDRVKWAFSVSEINGMVLVGLWLTQWLFLRYKSIVGRRFFFIMGTLYLYRCITMYVTTLPVPGMHFQCAPKLNGDSQAKIQRILRLLSGGGLSITGSHILCGDFLFSGHTVVLTLTYLFIKEYSPRHFWWYHLVCWLLSAAGIICILVAHEHYTVDVIIAYYITTRLFWWYHSMANEKNLKVSSQTNFLSRAWWFPIFYFFEKNVQGSIPCCFSWPLSWPPGCFKSSCKKYSRVQKIGEDNEKST", "length": 365 }, "evidence": [ { "id": "F1NLG9", "url": "https://omabrowser.org/oma/group/F1NLG9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8NHU3-1", "protein_name": "Phosphatidylcholine:ceramide cholinephosphotransferase 2", "gene_name": "SGMS2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDIIETAKLEEHLENQPSDPTNTYARPAEPVEEENKNGNGKPKSLSSGLRKGTKKYPDYIQIAMPTESRNKFPLEWWKTGIAFIYAVFNLVLTTVMITVVHERVPPKELSPPLPDKFFDYIDRVKWAFSVSEINGIILVGLWITQWLFLRYKSIVGRRFCFIIGTLYLYRCITMYVTTLPVPGMHFQCAPKLNGDSQAKVQRILRLISGGGLSITGSHILCGDFLFSGHTVTLTLTYLFIKEYSPRHFWWYHLICWLLSAAGIICILVAHEHYTIDVIIAYYITTRLFWWYHSMANEKNLKVSSQTNFLSRAWWFPIFYFFEKNVQGSIPCCFSWPLSWPPGCFKSSCKKYSRVQKIGEDNEKST", "length": 365 }, "evidence": [ { "id": "F1NLG9", "url": "https://omabrowser.org/oma/group/F1NLG9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9D4B1-1", "protein_name": "Phosphatidylcholine:ceramide cholinephosphotransferase 2", "gene_name": "Sgms2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDIIETAKLEGHLESQTNDSTNTYTSPTEAVEEEGKNGKGKPKTLSNGLRKGAKKYPDYIQISMPNDSKNKFPLEWWKTGIAFVYALFNLILTTVMITVVHERVPPKELSPPLPDKFFDYFDRVKWAFSVSEINGMVLVGLWITQWLFLRYKSIVGRRFFFIMGTLYLYRCITMYVTTLPVPGMHFQCAPKLNGDSQAKIQRILRLISGGGLSITGSHILCGDFLFSGHTVVLTLTYLFIKEYSPRHFWWYHLVCWLLSAAGIICILVAHEHYTVDVIIAYYITTRLFWWYHSMANEKNLKVSSQTNFLSRAWWFPIFYFFEKNVQGSIPCCFSWPLSWPPGCFKSSCRKYSRVQKIGEDNEKST", "length": 365 }, "evidence": [ { "id": "F1NLG9", "url": "https://omabrowser.org/oma/group/F1NLG9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "sphingomyelin biosynthetic process", "id": "GO:0006686", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006686", "evidence": [ { "database": "UniProtKB", "id": "F1NLG9", "url": "https://www.uniprot.org/uniprotkb/F1NLG9" } ], "pmid": "" }, { "name": "ceramide biosynthetic process", "id": "GO:0046513", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046513", "evidence": [ { "database": "UniProtKB", "id": "F1NLG9", "url": "https://www.uniprot.org/uniprotkb/F1NLG9" } ], "pmid": "" }, { "name": "regulation of bone mineralization", "id": "GO:0030500", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030500", "evidence": [ { "database": "UniProtKB", "id": "F1NLG9", "url": "https://www.uniprot.org/uniprotkb/F1NLG9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "ceramide phosphoethanolamine synthase activity", "id": "GO:0002950", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002950", "evidence": [ { "database": "UniProtKB", "id": "F1NLG9", "url": "https://www.uniprot.org/uniprotkb/F1NLG9" } ], "pmid": "" }, { "name": "sphingomyelin synthase activity", "id": "GO:0033188", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033188", "evidence": [ { "database": "UniProtKB", "id": "F1NLG9", "url": "https://www.uniprot.org/uniprotkb/F1NLG9" } ], "pmid": "" }, { "name": "ceramide cholinephosphotransferase activity", "id": "GO:0047493", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0047493", "evidence": [ { "database": "UniProtKB", "id": "F1NLG9", "url": "https://www.uniprot.org/uniprotkb/F1NLG9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "F1NLG9", "url": "https://www.uniprot.org/uniprotkb/F1NLG9" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F1NLG9", "url": "https://www.uniprot.org/uniprotkb/F1NLG9" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "F1NLG9", "url": "https://www.uniprot.org/uniprotkb/F1NLG9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 18, "end_pos": 20, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "36079", "name": "", "equation": "an N-acylsphing-4-enine + a 1,2-diacyl-sn-glycero-3-phosphoethanolamine = an N-acylsphing-4-enine 1-phosphoethanolamine + a 1,2-diacyl-sn-glycerol", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q7T3T4-1", "A0A3Q2U7T0-1", "A0A8V0ZPK7-1" ], "evidence": [ { "id": "36079", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/36079" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A3Q2U7T0", "gene_name": "SGMS1", "activity": [ { "ec_number": "2.7.8.27", "activity": "an N-acylsphing-4-enine + a 1,2-diacyl-sn-glycero-3-phosphocholine = a sphingomyelin + a 1,2-diacyl-sn-glycerol.", "evidence": [ { "id": "A0A3Q2U7T0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U7T0" } ] }, { "ec_number": "2.7.8.27", "activity": "", "evidence": [ { "id": "A0A3Q2U7T0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U7T0" } ] } ] }, { "uniprot_ac": "A0A8V0ZPK7", "gene_name": "SAMD8", "activity": [ { "ec_number": "3.1.4.62", "activity": "a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + H2O = phosphoethanolamine + a 1,2-diacyl-sn-glycerol + H(+).", "evidence": [ { "id": "A0A8V0ZPK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPK7" } ] }, { "ec_number": "3.1.4.62", "activity": "", "evidence": [ { "id": "A0A8V0ZPK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPK7" } ] } ] }, { "uniprot_ac": "Q7T3T4", "gene_name": "SGMS1", "activity": [ { "ec_number": "2.7.8.27", "activity": "an N-acylsphing-4-enine + a 1,2-diacyl-sn-glycero-3-phosphocholine = a sphingomyelin + a 1,2-diacyl-sn-glycerol.", "evidence": [ { "id": "Q7T3T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q7T3T4" } ] }, { "ec_number": "2.7.8.27", "activity": "", "evidence": [ { "id": "Q7T3T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q7T3T4" } ] } ] } ], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1NLG9-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 365, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1NLG9-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1NLG9" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1NLG9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NLG9" }, { "id": "PF14360", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14360" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Sphingomyelin synthase-like", "eco_id": "ECO_0000259", "start_pos": 221, "end_pos": 293, "start_aa": "Cys", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 18, "end_pos": 20 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": 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}, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1NLK0-1", "uniprot_ac": "F1NLK0", "uniprot_id": "F1NLK0_CHICK", "mass": { "chemical_mass": 63984.0, "monoisotopic_mass": 63984.0 }, "refseq": { "ac": "XP_015148241", "name": "guanine nucleotide-binding protein-like 3 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015148241" }, "gene_names": [ { "name": "GNL3", "type": "recommended", "evidence": [ { "id": "F1NLK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NLK0" } ] }, { "name": "GNL3", "type": "synonym", "evidence": [ { "id": "XP_015148241", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015148241" } ] } ], "protein_names": [ { "name": "Guanine nucleotide-binding protein-like 3", "type": "recommended", "evidence": [ { "id": "F1NLK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NLK0/entry#names_and_taxonomy" } ] }, { "name": "guanine nucleotide-binding protein-like 3 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015148241", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015148241" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052543.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015148241", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015148241" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NLK0", "url": "https://www.uniprot.org/uniprotkb/F1NLK0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "GNL3", "url": "https://www.uniprot.org/uniprotkb/F1NLK0", "locus": { "chromosome": "12", "start_pos": 842013, "end_pos": 833484, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010028051", "url": "https://www.ensembl.org/id/ENSGALG00010028051" } ] } } ], "crossref": [ { "id": "F1NLK0", "url": "https://alphafold.ebi.ac.uk/entry/F1NLK0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000001613", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000001613", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd04178", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04178", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "415897", "url": "https://www.ncbi.nlm.nih.gov/gene/415897", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006073", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006073", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014813", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014813", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR030378", "url": "https://www.ebi.ac.uk/interpro/entry/IPR030378", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050755", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050755", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:415897", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:415897", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "FKLDGLW", "url": "https://omabrowser.org/oma/group/FKLDGLW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1NLK0", "url": "https://www.orthodb.org/?gene=F1NLK0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11089", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11089", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11089:SF11", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11089:SF11", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01926", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01926", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08701", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08701", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015148241", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015148241", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1NLK0", "url": "https://www.uniprot.org/uniprotkb/F1NLK0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NLK0-1", "url": "https://www.uniprot.org/uniprotkb/F1NLK0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKRPKLRKASKRLTCHKRYKIQKKIREHHRKVRKEAKKRGRKKPRKDPGVPGAAPFKEALLREAELRKQRLEELKRKQKLDRQKELEKRRKLDAKRSAAAIQEQTEGKESSGKSEAKKTKKALDKNAKKSFHSELEKVIEASDVVLEVLDARDPMGCRCPQLEQAITCSGGEKKLLLVLNKIDLVPKENLEKWLNYLKKEFPTVAFKSATLLKDRNMQTFSRRRARIDLSRHTESFGSECLVKLLQEYGRTQDRAIQVGLVGFPNVGKSSIINSIKKDRVCDVGPARGVTKSMQAVRIDKQMKILDSPSIVADPTNSAVTLALRSIIHTGESCSVNMVKAVDAVLSHCNKQQVMMFYSIPDFKNTEELLSLLAQKRGMLKKGGVPDIENIAKSLLCDWTGAKISYHSEPPASQILPPYLTEDKIAEMQAGFNLKKLEEENSSTVQALKYPSPASSIVFQSAGMTNGKIVKNKVVEEESEWEDLETSHEEEDFMETDDDQDSIEKEEGNNVKEDGRTQMTRNAELGMGQTGHAHSENEIAESGLANSLSFSLDKTAGENDAYDFNTDYV", "length": 568, "header": "tr|F1NLK0-1|F1NLK0_CHICK Isoform 1 of Guanine nucleotide-binding protein-like 3 OS=Gallus gallus OX=9031 GN=GNL3 PE=1 SV=3 CANONICAL=F1NLK0-1" }, "isoforms": [ { "isoform_ac": "F1NLK0-1", "url": "https://www.uniprot.org/uniprotkb/F1NLK0/entry#F1NLK0-1", "sequence": { "sequence": "MKRPKLRKASKRLTCHKRYKIQKKIREHHRKVRKEAKKRGRKKPRKDPGVPGAAPFKEALLREAELRKQRLEELKRKQKLDRQKELEKRRKLDAKRSAAAIQEQTEGKESSGKSEAKKTKKALDKNAKKSFHSELEKVIEASDVVLEVLDARDPMGCRCPQLEQAITCSGGEKKLLLVLNKIDLVPKENLEKWLNYLKKEFPTVAFKSATLLKDRNMQTFSRRRARIDLSRHTESFGSECLVKLLQEYGRTQDRAIQVGLVGFPNVGKSSIINSIKKDRVCDVGPARGVTKSMQAVRIDKQMKILDSPSIVADPTNSAVTLALRSIIHTGESCSVNMVKAVDAVLSHCNKQQVMMFYSIPDFKNTEELLSLLAQKRGMLKKGGVPDIENIAKSLLCDWTGAKISYHSEPPASQILPPYLTEDKIAEMQAGFNLKKLEEENSSTVQALKYPSPASSIVFQSAGMTNGKIVKNKVVEEESEWEDLETSHEEEDFMETDDDQDSIEKEEGNNVKEDGRTQMTRNAELGMGQTGHAHSENEIAESGLANSLSFSLDKTAGENDAYDFNTDYV", "length": 568, "header": "tr|F1NLK0-1|F1NLK0_CHICK Isoform 1 of Guanine nucleotide-binding protein-like 3 OS=Gallus gallus OX=9031 GN=GNL3 PE=1 SV=3 CANONICAL=F1NLK0-1" }, "locus": { "chromosome": "12", "start_pos": 841320, "end_pos": 833547, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067973.1", "url": "https://www.ensembl.org/id/ENSGALT00010067973.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041716.1", "url": "https://www.ensembl.org/id/ENSGALP00010041716.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:415897", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:415897", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A9J7F2E1-1", "protein_name": "Guanine nucleotide-binding protein-like 3", "gene_name": "Gnl3", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MKRPKLKKASKRMTCHKRYKIQKKVREHHRKLRKEAKKRGHKKPRKDPGIPNSAPFKEALLREAELRKQQLEELKQQQKLDRQKEQERKRKHEVNPGDEQSNVEPHQEFEEPKSKKAKPGKQNPKKLHCQELKKVIEASDVVLEVLDARDPLGCRCPQVEEAIVQSGHKKLILVLNKSDLVPKENLENWLNYLSKELPTVVFKASTDMKSKEKMLKAKKKAVPFQRKLCSGKEALCKLLRSFQQSCGKDIQVGVIGFPNVGKSSIINSLKQERICTVGVPMGLTRSMQIVPLDKQITVIDSPCFIISPCNSSAALALRSPVSIEVLRPLEAASAILSQADSQQTRFVFKVVLKYTVPGYKDSLDFFTKLAQKRGLHQKGGSPNIESAAKLLWSEWTGASLGYYCHPPASWNPPHFNENIAANMKKGFNLEELETNNAHSIQVLKGPRLANRILFRSSGPTNGIIEETDIPEELPRQKENKQNTEDQGNDENNAESSGVPPVEDAREMLPVESTANKPPDRSFTLDEMSQEDDDYDFKTDYL", "length": 541 }, "evidence": [ { "id": "F1NLK0", "url": "https://omabrowser.org/oma/group/F1NLK0/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P40010-1", "protein_name": "Nuclear GTP-binding protein NUG1", "gene_name": "NUG1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MRVRKRQSRRTSTKLKEGIKKKASAHRKKEKKMAKKDVTWRSRSKKDPGIPSNFPYKAKILEEIEAKKMKDLEERELAKQQRLEARKAAKEQGVDAMDEDMIEDDENGLAALVESAQQAAAEYEGTPSNDADVRDDELDVIDYNIDFYGEDVEGESELEKSRKAYDKIFKSVIDASDVILYVLDARDPESTRSRKVEEAVLQSQGKRLILILNKVDLIPPHVLEQWLNYLKSSFPTIPLRASSGAVNGTSFNRKLSQTTTASALLESLKTYSNNSNLKRSIVVGVIGYPNVGKSSVINALLARRGGQSKACPVGNEAGVTTSLREIKIDNKLKILDSPGICFPSENKKRSKVEHEAELALLNALPAKHIVDPYPAVLMLVKRLAKSDEMTESFKKLYEIPPIPANDADTFTKHFLIHVARKRGRLGKGGIPNLASAGLSVLNDWRDGKILGWVLPNTSAAASQQDKQNLSTINTGTKQAPIAANESTIVSEWSKEFDLDGLFSSLDKAIDASKDQDTMME", "length": 520 }, "evidence": [ { "id": "F1NLK0", "url": "https://omabrowser.org/oma/group/F1NLK0/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q54KS4-1", "protein_name": "Guanine nucleotide-binding protein-like 3 homolog", "gene_name": "gnl3", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MGKQTASKRQSLHHKHKVLKKVAEHHRKVKRFAKQHPELNKSRKDPGIPNLWPFKEDMLNKIEQQKQKASEEKKNKKEKRRLEQMAEARRDIASMAADAKRRESEFQERQQLKQQQKQQGKFEKEGKDSSLKQFYREVKKVIEAGDVILQVLDARDPMGCRCLEIEKMILERYTNKKIVLILNKIDLVPRENVLMWLKYLRNFYPTLAFKCSTQQQKRNLGQQGGIQPELASNDMLNSTESLGAEQLLQLLKNYSRSLNIKTSVTVGIIGYPNVGKSSLINSLKRTRSVGVGATPGFTKFAQEVHLDKNVKLLDSPGIVPIKGNVDENIILRNVVKLEKVLDPIAPVDAILSRCSQKQILDIYEIAQYQSTTDFLTQVAAKRKKIVKGGIADLRSTAISVIRDWTGGKIPFYTQPPKVLVKSTLLSQFSDELNIDQSDLISTVSNQNTSFASLKYLEPKQQELDNSLFDDDDEEDEEEMEDEDEDDDEEEEEEMEDEEDEEDEEDEEDEDEMEEDSDSEALLKYQQQKQVVKATAKQVAQIKSKSQNLKDENDQFNPQSNKQLKKQNKKLKKKFGIVSTSSKQVQDDDDEDDDDEQEEIDQDDEDDEDIDEDEAF", "length": 615 }, "evidence": [ { "id": "F1NLK0", "url": "https://omabrowser.org/oma/group/F1NLK0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q811S9-1", "protein_name": "Guanine nucleotide-binding protein-like 3", "gene_name": "Gnl3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKRPKLKKASKRMTCHKRYKIQKKVREHHRKLRKEAKKRGHKKPKKDPGVPNSAPFKEALLREAELRKQQLEELKQQQKLDRQKEQERKRKLEISPDDEQSNVETQEESDEPKIKKAKSGKQNPKKLHCQELKKVIEASDIVLEVLDARDPLGCRCPQVEEAVIQSGCKKLVLVLNKSDLVPKENLENWLTYLNKELPTVVFKASTNLKNRKKTFKIKKKVVPFQSKLCCGKEALWKLLGGFQQSCGKGVQVGVVGFPNVGKSSIINSLKQERICSVGVSMGLTRSMQIVPLDKQITIIDSPCFIISPCNSPAALALRSPASIEVLRPLEAASAILSQADSQQVVLKYTVPGYKDSLDFFTKLAQRRGLHQKGGSPNVESAAKLLWSEWTGASLGYYCHPPASWNHSPHFNENITAIMKRGFNLEELEKNNAHSIQVLKGPHLTNKILFRSSGLTNGILEEKDIPEESPKQTEDQQDGDDQEHVTGEKNAEISDVTPVEETREMSPGQSTASKPSDRSFILDKMSEEDDAYDFTTDYI", "length": 538 }, "evidence": [ { "id": "F1NLK0", "url": "https://omabrowser.org/oma/group/F1NLK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8CI11-1", "protein_name": "Guanine nucleotide-binding protein-like 3", "gene_name": "Gnl3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKRPKLKKASKRMTCHKRYKIQKKVREHHRKLRKEAKKRGHKKPRKDPGVPNSAPFKEALLREAELRKQQLEELKQQQKLDRQKEQERKRKLEVSPGDEQSNVETREESDEPKRKKAKAGKQNPKKLHCQELKKVIEASDIVLEVLDARDPLGCRCPQIEEAVIQSGSKKLILVLNKSDLVPKENLENWLNYLNKELPTVVFKASTNLKNRKTFKIKKKKVVPFQSKICCGKEALWKLLGDFQQSCGKDIQVGVIGFPNVGKSSVINSLKQEWICNVGISMGLTRSMQIVPLDKQITIIDSPCLIISPCNSPTALALRSPASIEELRPLEAASAILSQADNEQVVLKYTVPEYKDSLHFFTKLAQRRGLHQKGGSPNVESAAKLVWSEWTGASLGYYCHPPASWNHSLHFNENIAAVMKKGFNLEELEKNNAHSIQVLKGPHLTNRILFRSSGLTNGILDEKDIVEESPRQTEDKQDADDQENGSGERNAEISDVAPVEETRELSPEQSTAGKPSDGSSALDRASQEDETYDFTTDYI", "length": 538 }, "evidence": [ { "id": "F1NLK0", "url": "https://omabrowser.org/oma/group/F1NLK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9BVP2-1", "protein_name": "Guanine nucleotide-binding protein-like 3", "gene_name": "GNL3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKRPKLKKASKRMTCHKRYKIQKKVREHHRKLRKEAKKRGHKKPRKDPGVPNSAPFKEALLREAELRKQRLEELKQQQKLDRQKELEKKRKLETNPDIKPSNVEPMEKEFGLCKTENKAKSGKQNSKKLYCQELKKVIEASDVVLEVLDARDPLGCRCPQVEEAIVQSGQKKLVLILNKSDLVPKENLESWLNYLKKELPTVVFRASTKPKDKGKITKRVKAKKNAAPFRSEVCFGKEGLWKLLGGFQETCSKAIRVGVIGFPNVGKSSIINSLKQEQMCNVGVSMGLTRSMQVVPLDKQITIIDSPSFIVSPLNSSSALALRSPASIEVVKPMEAASAILSQADARQVVLKYTVPGYRNSLEFFTVLAQRRGMHQKGGIPNVEGAAKLLWSEWTGASLAYYCHPPTSWTPPPYFNESIVVDMKSGFNLEELEKNNAQSIRAIKGPHLANSILFQSSGLTNGIIEEKDIHEELPKRKERKQEEREDDKDSDQETVDEEVDENSSGMFAAEETGEALSEETTAGEQSTRSFILDKIIEEDDAYDFSTDYV", "length": 549 }, "evidence": [ { "id": "F1NLK0", "url": "https://omabrowser.org/oma/group/F1NLK0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9M8Z5-1", "protein_name": "Guanine nucleotide-binding protein-like NSN1", "gene_name": "NSN1", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MVKRSKKSKSKRVTLKQKHKVLKKVKEHHKKKAKDAKKLGLHRKPRVEKDPGIPNDWPFKEQELKALEVRRARALEEIEQKKEARKERAKKRKLGLVDDEDTKTEGETIEDLPKVVNVRDNSERAFYKELVKVIELSDVILEVLDARDPLGTRCTDMERMVMQAGPNKHLVLLLNKIDLVPREAAEKWLMYLREEFPAVAFKCSTQEQRSNLGWKSSKASKPSNMLQTSDCLGADTLIKLLKNYSRSHELKKSITVGIIGLPNVGKSSLINSLKRAHVVNVGATPGLTRSLQEVHLDKNVKLLDCPGVVMLKSSGNDASIALRNCKRIEKLDDPVSPVKEILKLCPKDMLVTLYKIPSFEAVDDFLYKVATVRGKLKKGGLVDIDAAARIVLHDWNEGKIPYYTMPPKRDQGGHAESKIVTELAKDFNIDEVYSGESSFIGSLKTVNEFNPVIIPSNGPLNFDETMIEDESKTQTEEEAEHESDDDESMGGEEEEEAGKTKEKSETGRQNVKLYAAESMLNTKKQKAEKKKRKKAKKAGADEEDLMDGDYDFKVDYRKNKDGEDEEFQIDAKIPMAGLLPEE", "length": 582 }, "evidence": [ { "id": "F1NLK0", "url": "https://omabrowser.org/oma/group/F1NLK0/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "positive regulation of protein localization to chromosome, telomeric region", "id": "GO:1904816", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904816", "evidence": [ { "database": "UniProtKB", "id": "F1NLK0", "url": "https://www.uniprot.org/uniprotkb/F1NLK0" } ], "pmid": "" }, { "name": "stem cell population maintenance", "id": "GO:0019827", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019827", "evidence": [ { "database": "UniProtKB", "id": "F1NLK0", "url": "https://www.uniprot.org/uniprotkb/F1NLK0" } ], "pmid": "" }, { "name": "positive regulation of protein sumoylation", "id": "GO:0033235", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033235", "evidence": [ { "database": "UniProtKB", "id": "F1NLK0", "url": "https://www.uniprot.org/uniprotkb/F1NLK0" } ], "pmid": "" }, { "name": "stem cell division", "id": "GO:0017145", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017145", "evidence": [ { "database": "UniProtKB", "id": "F1NLK0", "url": "https://www.uniprot.org/uniprotkb/F1NLK0" } ], "pmid": "" }, { "name": "positive regulation of miRNA transcription", "id": "GO:1902895", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902895", "evidence": [ { "database": "UniProtKB", "id": "F1NLK0", "url": "https://www.uniprot.org/uniprotkb/F1NLK0" } ], "pmid": "" }, { "name": "positive regulation of telomere maintenance", "id": "GO:0032206", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032206", "evidence": [ { "database": "UniProtKB", "id": "F1NLK0", "url": "https://www.uniprot.org/uniprotkb/F1NLK0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "F1NLK0", "url": "https://www.uniprot.org/uniprotkb/F1NLK0" } ], "pmid": "" }, { "name": "mRNA 5'-UTR binding", "id": "GO:0048027", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048027", "evidence": [ { "database": "UniProtKB", "id": "F1NLK0", "url": "https://www.uniprot.org/uniprotkb/F1NLK0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "F1NLK0", "url": "https://www.uniprot.org/uniprotkb/F1NLK0" } ], "pmid": "" }, { "name": "nuclear body", "id": "GO:0016604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016604", "evidence": [ { "database": "UniProtKB", "id": "F1NLK0", "url": "https://www.uniprot.org/uniprotkb/F1NLK0" } ], "pmid": "" }, { "name": "chromosome", "id": "GO:0005694", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005694", "evidence": [ { "database": "UniProtKB", "id": "F1NLK0", "url": "https://www.uniprot.org/uniprotkb/F1NLK0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 440, "end_pos": 442, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1NLK0-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 568, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1NLK0-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1NLK0" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 440, "end_pos": 442 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1NLL4-1", "uniprot_ac": "F1NLL4", "uniprot_id": "F1NLL4_CHICK", "mass": { "chemical_mass": 14403.0, "monoisotopic_mass": 14403.0 }, "refseq": { "ac": "NP_001025733", "name": "nuclear transport factor 2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025733" }, "gene_names": [ { "name": "NUTF2", "type": "recommended", "evidence": [ { "id": "F1NLL4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NLL4" } ] }, { "name": "NUTF2", "type": "synonym", "evidence": [ { "id": "NP_001025733", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025733" } ] } ], "protein_names": [ { "name": "Nuclear transport factor 2", "type": "recommended", "evidence": [ { "id": "F1NLL4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NLL4/entry#names_and_taxonomy" } ] }, { "name": "NTF-2", "type": "synonym", "evidence": [ { "id": "F1NLL4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NLL4/entry#names_and_taxonomy" } ] }, { "name": "nuclear transport factor 2", "type": "synonym", "evidence": [ { "id": "NP_001025733", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025733" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## CDS exon combination :: AJ719600.1, BU121030.1 [ECO:0000331] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992393 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AJ719600.1 and BU144410.1. On Mar 18, 2015 this sequence version replaced NP_001025733.1. Transcript Variant: This variant (3) differs in the 5' UTR, compared to variant 1. Variants 1-3 encode the same protein.", "evidence": [ { "database": "RefSeq", "id": "NP_001025733", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025733" } ] }, { "annotation": "Has a role in nuclear-cytoplasmic transport of proteins and mRNAs.", "evidence": [ { "database": "UniProtKB", "id": "F1NLL4", "url": "https://www.uniprot.org/uniprotkb/F1NLL4#function" }, { "database": "UniProtKB", "id": "RU369002", "url": "https://www.uniprot.org/uniprotkb/RU369002#function" }, { "database": "UniProtKB", "id": "A0A8V0ZTE4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTE4#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NLL4", "url": "https://www.uniprot.org/uniprotkb/F1NLL4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "NUTF2", "url": "https://www.uniprot.org/uniprotkb/F1NLL4", "locus": { "chromosome": "11", "start_pos": 938855, "end_pos": 917080, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021887", "url": "https://www.ensembl.org/id/ENSGALG00010021887" } ] } } ], "crossref": [ { "id": "F1NLL4", "url": "https://alphafold.ebi.ac.uk/entry/F1NLL4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000001602", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000001602", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00780", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00780", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "415655", "url": "https://www.ncbi.nlm.nih.gov/gene/415655", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002075", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002075", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018222", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018222", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032710", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032710", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045875", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045875", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:415655", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:415655", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QFVEYYY", "url": "https://omabrowser.org/oma/group/QFVEYYY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZTE4", "url": "https://www.orthodb.org/?gene=A0A8V0ZTE4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NLL4", "url": "https://www.orthodb.org/?gene=F1NLL4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12612", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12612", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02136", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02136", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001025733", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025733", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZTE4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTE4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZTE4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTE4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NLL4", "url": "https://www.uniprot.org/uniprotkb/F1NLL4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NLL4-1", "url": "https://www.uniprot.org/uniprotkb/F1NLL4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGDKPIWEQIGSSFVQHYYQLFDADRTQLGAIYIDASCLTWEGQQFQGKAAIVEKLSSLPFQKIQHSITAQDHQPTPDSCILSMVVGQLKADEDPIMGFHQIFLLKNINDAWVCTNDMFRLALHNFG", "length": 127, "header": "tr|F1NLL4-1|F1NLL4_CHICK Isoform 1 of Nuclear transport factor 2 OS=Gallus gallus OX=9031 GN=NUTF2 PE=1 SV=3 CANONICAL=F1NLL4-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZTE4-1", "url": "https://www.uniprot.org/uniprotkb/F1NLL4/entry#A0A8V0ZTE4-1", "sequence": { "sequence": "MGDKPIWEQIGSSFVQHYYQLFDADRTQLGAIYIDASCLTWEGQQFQGKAAIVEKLSSLPFQKIQHSITAQDHQPTPDSCILSMVVGQLKADDDQVLGFQQTFLLKNIQGAWVCTNEVFRLALHNV", "length": 126, "header": "tr|A0A8V0ZTE4-1|A0A8V0ZTE4_CHICK Computationally mapped isoform of Nuclear transport factor 2 OS=Gallus gallus OX=9031 GN=NUTF2 PE=1 SV=1 CANONICAL=F1NLL4-1" }, "locus": { "chromosome": "11", "start_pos": 934108, "end_pos": 925848, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053242.1", "url": "https://www.ensembl.org/id/ENSGALT00010053242.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032088.1", "url": "https://www.ensembl.org/id/ENSGALP00010032088.1" } ] } }, { "isoform_ac": "F1NLL4-1", "url": "https://www.uniprot.org/uniprotkb/F1NLL4/entry#F1NLL4-1", "sequence": { "sequence": "MGDKPIWEQIGSSFVQHYYQLFDADRTQLGAIYIDASCLTWEGQQFQGKAAIVEKLSSLPFQKIQHSITAQDHQPTPDSCILSMVVGQLKADEDPIMGFHQIFLLKNINDAWVCTNDMFRLALHNFG", "length": 127, "header": "tr|F1NLL4-1|F1NLL4_CHICK Isoform 1 of Nuclear transport factor 2 OS=Gallus gallus OX=9031 GN=NUTF2 PE=1 SV=3 CANONICAL=F1NLL4-1" }, "locus": { "chromosome": "11", "start_pos": 938445, "end_pos": 925848, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053250.1", "url": "https://www.ensembl.org/id/ENSGALT00010053250.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032093.1", "url": "https://www.ensembl.org/id/ENSGALP00010032093.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:415655", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:415655", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "G3HKX2-1", "protein_name": "Nuclear transport factor 2", "gene_name": "Nutf2", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MGDKPIWEQIGSSFIQHYYQLFDNDRTQLGAIYIDASCLTWEGQQFQGKAAIVEKLSSLPFQKIQHSITAQDHQPTPDSCIISMVVGQLKADEDPIMGFHQMFLLKNINDAWVCTNDMFRLALHNFG", "length": 127 }, "evidence": [ { "id": "F1NLL4", "url": "https://omabrowser.org/oma/group/F1NLL4/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P33331-1", "protein_name": "Nuclear transport factor 2", "gene_name": "NTF2", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSLDFNTLAQNFTQFYYNQFDTDRSQLGNLYRNESMLTFETSQLQGAKDIVEKLVSLPFQKVQHRITTLDAQPASPNGDVLVMITGDLLIDEEQNPQRFSQVFHLIPDGNSYYVFNDIFRLNYSA", "length": 125 }, "evidence": [ { "id": "F1NLL4", "url": "https://omabrowser.org/oma/group/F1NLL4/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P61970-1", "protein_name": "Nuclear transport factor 2", "gene_name": "NUTF2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGDKPIWEQIGSSFIQHYYQLFDNDRTQLGAIYIDASCLTWEGQQFQGKAAIVEKLSSLPFQKIQHSITAQDHQPTPDSCIISMVVGQLKADEDPIMGFHQMFLLKNINDAWVCTNDMFRLALHNFG", "length": 127 }, "evidence": [ { "id": "F1NLL4", "url": "https://omabrowser.org/oma/group/F1NLL4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P61971-1", "protein_name": "Nuclear transport factor 2", "gene_name": "Nutf2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGDKPIWEQIGSSFIQHYYQLFDNDRTQLGAIYIDASCLTWEGQQFQGKAAIVEKLSSLPFQKIQHSITAQDHQPTPDSCIISMVVGQLKADEDPIMGFHQMFLLKNINDAWVCTNDMFRLALHNFG", "length": 127 }, "evidence": [ { "id": "F1NLL4", "url": "https://omabrowser.org/oma/group/F1NLL4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P61972-1", "protein_name": "Nuclear transport factor 2", "gene_name": "Nutf2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGDKPIWEQIGSSFIQHYYQLFDNDRTQLGAIYIDASCLTWEGQQFQGKAAIVEKLSSLPFQKIQHSITAQDHQPTPDSCIISMVVGQLKADEDPIMGFHQMFLLKNINDAWVCTNDMFRLALHNFG", "length": 127 }, "evidence": [ { "id": "F1NLL4", "url": "https://omabrowser.org/oma/group/F1NLL4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q32KP9-1", "protein_name": "Nuclear transport factor 2", "gene_name": "NUTF2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGDKPIWEQIGSSFIQHYYQLFDNDRTQLGAIYIDASCLTWEGQQFQGKAAIVEKLSSLPFQKIQHSITAQDHQPTPDSCIISMVVGQLKADEDPIMGFHQMFLLKNINDAWVCTNDMFRLALHNFG", "length": 127 }, "evidence": [ { "id": "F1NLL4", "url": "https://omabrowser.org/oma/group/F1NLL4/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q86HW7-1", "protein_name": "Nuclear transport factor 2", "gene_name": "nutf2", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MQSVDPQVVGVGKQFVEHYYGIFDSNRAGLTQIYQQQTTLTWEGKFLSGADAIVKHIVELPFQQTNRKINSIDCQQTYQPGIMITVTGTLIIDGEAKNQLKFVQVFNLASNNGSFLLINDFFRLVLD", "length": 127 }, "evidence": [ { "id": "F1NLL4", "url": "https://omabrowser.org/oma/group/F1NLL4/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q9C7F5-1", "protein_name": "Nuclear transport factor 2B", "gene_name": "NTF2B", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSQMDPDAVSKAFVEHYYSTFDTNRVGLAGLYQEASMLTFEGQKIQGVQSIVAKLTSLPFQQCKHHISTVDCQPSGPASGMLVFVSGNLQLAGEEHALKFSQMFHLMPTPQGSFYVFNDIFRLNYA", "length": 126 }, "evidence": [ { "id": "F1NLL4", "url": "https://omabrowser.org/oma/group/F1NLL4/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9VRD6-1", "protein_name": "NTF2-related export protein", "gene_name": "Ntf-2", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSLNPQYEDIGKGFVQQYYAIFDDPANRANVVNFYSATDSFMTFEGHQIQGAPKILEKVQSLSFQKITRVITTVDSQPTFDGGVLINVLGRLQCDDDPPHAFSQVFFLKANAGTFFVAHDIFRLNIHNSA", "length": 130 }, "evidence": [ { "id": "F1NLL4", "url": "https://omabrowser.org/oma/group/F1NLL4/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "F1NLL4", "url": "https://www.uniprot.org/uniprotkb/F1NLL4" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F1NLL4", "url": "https://www.uniprot.org/uniprotkb/F1NLL4" } ], "pmid": "" }, { "name": "nuclear pore central transport channel", "id": "GO:0044613", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044613", "evidence": [ { "database": "UniProtKB", "id": "F1NLL4", "url": "https://www.uniprot.org/uniprotkb/F1NLL4" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1NLL4", "url": "https://www.uniprot.org/uniprotkb/F1NLL4" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1NLL4", "url": "https://www.uniprot.org/uniprotkb/F1NLL4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "F1NLL4", "url": "https://www.uniprot.org/uniprotkb/F1NLL4" } ], "pmid": "" }, { "name": "small GTPase binding", "id": "GO:0031267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031267", "evidence": [ { "database": "UniProtKB", "id": "F1NLL4", "url": "https://www.uniprot.org/uniprotkb/F1NLL4" } ], "pmid": "" }, { "name": "structural constituent of nuclear pore", "id": "GO:0017056", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017056", "evidence": [ { "database": "UniProtKB", "id": "F1NLL4", "url": "https://www.uniprot.org/uniprotkb/F1NLL4" } ], "pmid": "" }, { "name": "nuclear import signal receptor activity", "id": "GO:0061608", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061608", "evidence": [ { "database": "UniProtKB", "id": "F1NLL4", "url": "https://www.uniprot.org/uniprotkb/F1NLL4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "protein export from nucleus", "id": "GO:0006611", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006611", "evidence": [ { "database": "UniProtKB", "id": "F1NLL4", "url": "https://www.uniprot.org/uniprotkb/F1NLL4" } ], "pmid": "" }, { "name": "mRNA transport", "id": "GO:0051028", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051028", "evidence": [ { "database": "UniProtKB", "id": "F1NLL4", "url": "https://www.uniprot.org/uniprotkb/F1NLL4" } ], "pmid": "" }, { "name": "protein import into nucleus", "id": "GO:0006606", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006606", "evidence": [ { "database": "UniProtKB", "id": "F1NLL4", "url": "https://www.uniprot.org/uniprotkb/F1NLL4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1NLL4-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 127, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1NLL4-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1NLL4" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1NLR1-1", "uniprot_ac": "F1NLR1", "uniprot_id": "F1NLR1_CHICK", "mass": { "chemical_mass": 73596.0, "monoisotopic_mass": 73596.0 }, "refseq": { "ac": "XP_415011", "name": "acetyl-coenzyme A synthetase 2-like, mitochondrial isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_415011" }, "gene_names": [ { "name": "ACSS1A", "type": "recommended", "evidence": [ { "id": "F1NLR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NLR1" } ] }, { "name": "ACSS1A", "type": "synonym", "evidence": [ { "id": "XP_415011", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_415011" } ] } ], "protein_names": [ { "name": "Acetyl-coenzyme A synthetase", "type": "recommended", "evidence": [ { "id": "F1NLR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NLR1/entry#names_and_taxonomy" } ] }, { "name": "6.2.1.1", "type": "synonym", "evidence": [ { "id": "F1NLR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NLR1/entry#names_and_taxonomy" } ] }, { "name": "acetyl-coenzyme A synthetase 2-like, mitochondrial isoform X1", "type": "synonym", "evidence": [ { "id": "XP_415011", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_415011" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052534.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jan 4, 2016 this sequence version replaced XP_415011.4. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_415011", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_415011" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NLR1", "url": "https://www.uniprot.org/uniprotkb/F1NLR1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ACSS1A", "url": "https://www.uniprot.org/uniprotkb/F1NLR1", "locus": {} } ], "crossref": [ { "id": "F1NLR1", "url": "https://alphafold.ebi.ac.uk/entry/F1NLR1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000008632", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000008632", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd05966", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05966", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "416714", "url": "https://www.ncbi.nlm.nih.gov/gene/416714", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000873", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000873", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011904", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011904", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020845", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020845", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR025110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032387", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032387", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042099", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042099", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045851", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045851", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "AIKASWP", "url": "https://omabrowser.org/oma/group/AIKASWP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1NLR1", "url": "https://www.orthodb.org/?gene=F1NLR1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24095", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24095", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24095:SF110", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24095:SF110", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00501", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00501", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13193", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13193", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16177", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16177", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-71384", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-71384", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_415011", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_415011", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "20373", "url": "https://www.rhea-db.org/rhea/20373", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "23176", "url": "https://www.rhea-db.org/rhea/23176", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "F1NLR1", "url": "https://www.uniprot.org/uniprotkb/F1NLR1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NLR1-1", "url": "https://www.uniprot.org/uniprotkb/F1NLR1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MALAAVRARVLRSLSRPPFAARRCSGPAHLPPGCYGAWQERAARDPAAFWADAARGALRWDSPFHTACEAAPAGAGARWFLGGRLNVSVNCLDQHVEKSPNRVALIWERDEPGTAVHVTYRELLDLTCRLANTLKKYGIQKGDKVAIYMSVSPLSVAAMLACARIGAVHTVVFAGFSAESLAGRIMDSECKAVITYNQGVRGGRIIELKTTVDEAVKNCPSVKHVFVAQRTDNKTQMGDLDVPLEEEMAKAASVCTPESMDSEDMLFMLYTSGSTGKPKGIVHTQAGYLLYAALTHKYVFDYQQGDVFGCVADIGWITGHSYVVYGPLCNGGTTVLFESTPVYPDPGRYWEMVQRLKINQFYGAPTAIRLLLNYGDKWVKKYDRSSLKTLGSVGEPINNEAWQWFYHVVGEGRCTLVDTWWQTETGGICIAPRPSEENADIIPAMAMRPFFGISPVLMDENGKVLEGNDVSGALCITQPWPGLARTIYRDHQRFVDTYFKAYPGYYFTGDGAYRTKEGYYQITGRMDDVINISGHRLGTAEIEDAMADHPDVPETAVIGYPHEIKGEGAFAFIVLKEQTAHTDHVKEELKTIVATKIAKYAVPDHILVVKRLPKTRSGKIMRRLLRKVVTEQSSNMGDVTTLDDPTVVKEILDAYQKYKKEKSSS", "length": 665, "header": "tr|F1NLR1-1|F1NLR1_CHICK Isoform 1 of Acetyl-coenzyme A synthetase OS=Gallus gallus OX=9031 GN=ACSS1A PE=1 SV=3 CANONICAL=F1NLR1-1" }, "isoforms": [ { "isoform_ac": "F1NLR1-1", "url": "https://www.uniprot.org/uniprotkb/F1NLR1/entry#F1NLR1-1", "sequence": { "sequence": "MALAAVRARVLRSLSRPPFAARRCSGPAHLPPGCYGAWQERAARDPAAFWADAARGALRWDSPFHTACEAAPAGAGARWFLGGRLNVSVNCLDQHVEKSPNRVALIWERDEPGTAVHVTYRELLDLTCRLANTLKKYGIQKGDKVAIYMSVSPLSVAAMLACARIGAVHTVVFAGFSAESLAGRIMDSECKAVITYNQGVRGGRIIELKTTVDEAVKNCPSVKHVFVAQRTDNKTQMGDLDVPLEEEMAKAASVCTPESMDSEDMLFMLYTSGSTGKPKGIVHTQAGYLLYAALTHKYVFDYQQGDVFGCVADIGWITGHSYVVYGPLCNGGTTVLFESTPVYPDPGRYWEMVQRLKINQFYGAPTAIRLLLNYGDKWVKKYDRSSLKTLGSVGEPINNEAWQWFYHVVGEGRCTLVDTWWQTETGGICIAPRPSEENADIIPAMAMRPFFGISPVLMDENGKVLEGNDVSGALCITQPWPGLARTIYRDHQRFVDTYFKAYPGYYFTGDGAYRTKEGYYQITGRMDDVINISGHRLGTAEIEDAMADHPDVPETAVIGYPHEIKGEGAFAFIVLKEQTAHTDHVKEELKTIVATKIAKYAVPDHILVVKRLPKTRSGKIMRRLLRKVVTEQSSNMGDVTTLDDPTVVKEILDAYQKYKKEKSSS", "length": 665, "header": "tr|F1NLR1-1|F1NLR1_CHICK Isoform 1 of Acetyl-coenzyme A synthetase OS=Gallus gallus OX=9031 GN=ACSS1A PE=1 SV=3 CANONICAL=F1NLR1-1" }, "locus": { "chromosome": "3", "start_pos": 15572605, "end_pos": 15540505, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010045687.1", "url": "https://www.ensembl.org/id/ENSGALT00010045687.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027237.1", "url": "https://www.ensembl.org/id/ENSGALP00010027237.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "R-GGA-71384", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-71384", "resource": "Reactome", "description": "Ethanol oxidation" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZZN3-1", "protein_name": "Acetyl-coenzyme A synthetase", "gene_name": "Acss1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAARSLGSGVGRLLRGLHGHSGQSGWLLSLSRWTTTRFLGSVPAAAQLGSYPALSAQAAQEPAAFWGPLARDTLVWDTPYHTVWDCDFRTGKIGWFLGGQLNVSVNCLDQHVQKSPDTIALIWERDEPGTEVRITYRELLETTCRLANTLKRHGVHRGDRVAIYMPVSPLAVAAMLACARIGAIHTVVFAGFSAESLAGRINDAKCKVVITFNQGLRGGRVVELKKIVDEAVKNCPTVQHVLVAHRTDTKVPMGNLDIPLEQEMANEAPVCTPESMNSEDMLFMLYTSGSTGTPKGLVHTQAGYLLYAAMTHKLVFDYHPGDVFGCVADIGWITGHSYVVYGPLCNGATTVLFESTPVYPDAGRYWETVQRLKINQFYGAPTAVRLLLKFGDAWVKKYDRSSLRTLGSVGEPINHEAWEWLHKVVGDGRCTLVDTWWQTETGGICIAPRPSEDGAEILPGMAMRPFFGIVPALMDEKGNVVEGGDVSGALCISQAWPGMARTIYGDHQRFVDAYFRTYPGYYFTGDGAHRTEGGYYQITGRMDDVINISGHRLGTAEIEDAMADHPAVPETAVIGYPHDIKGEAAFAFIVLKDDVRDANVVVNELKLAVATKIAKYAVPDQILVVKRLPKTRSGKVMRRLLRKIITSRGQDLGDTTTLEDPSVITEIMSAFREYEEQRAATN", "length": 682 }, "evidence": [ { "id": "F1NLR1", "url": "https://omabrowser.org/oma/group/F1NLR1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1QYS7-1", "protein_name": "Acetyl-coenzyme A synthetase", "gene_name": "acss1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAGRVSASLLNSLTRGTILFKNKKCLRRSVVFISRCHARSLSRSSISAAQLDLSSHLSGRNYADLYELSVKDPENFWGSIAKERLAWTKPFDQVSDCDISSGKINWFLGGQLNVSVNCLDVHVANDPSRVALIWEKDEPGTEERITYRELLEMTCRLANTLKSHGVQRGERVAIYMPVSPMAVAAMLACARIGAVHTVVFAGFSSEALAGRIQDAQCKFVITCNQGVRGGRVFDLKSTVDKAVKSCPSVRHVFVAKRTNNSVPMGKLDIPLEEVMAGQSSECAPEPMESEEMLFMLYTSGSTGKPKGIVHTQAGYLLYASLTHQYVFDYTPGDVFGCVADIGWITGHSYVVYGPLCNGATSVLFESTPVYPNPGRYWETVQRLRINQFYGAPTAIRLLLKYEESWVKKYDRSSLKTLASVGEPINHEAWDWFHNVVGDGRCPLVDTWWQTETGGVCIAPLPAEPGAEIRPAMAMRPFFGIKPELLGEKGQIITGNDVNGALCISQPWPGMARTIFGDHQRFVDAYFKPYQGQYFTGDGAYRTEDGYYQITGRMDDVINISGHRLGTAEIEDALDEHPDVPETAVIGIPHEIKGEVPFAFVVLKESAAENQQAVVNELRHLVASKIAKYAVPDHFLVVKRLPKTRSGKIMRRILRKVAVQDTSNLGDVSTLDDPSVVSEIIKAHKHYRSLAAKQ", "length": 693 }, "evidence": [ { "id": "F1NLR1", "url": "https://omabrowser.org/oma/group/F1NLR1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q01574-1", "protein_name": "Acetyl-coenzyme A synthetase 1", "gene_name": "ACS1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSPSAVQSSKLEEQSSEIDKLKAKMSQSAATAQQKKEHEYEHLTSVKIVPQRPISDRLQPAIATHYSPHLDGLQDYQRLHKESIEDPAKFFGSKATQFLNWSKPFDKVFIPDPKTGRPSFQNNAWFLNGQLNACYNCVDRHALKTPNKKAIIFEGDEPGQGYSITYKELLEEVCQVAQVLTYSMGVRKGDTVAVYMPMVPEAIITLLAISRIGAIHSVVFAGFSSNSLRDRINDGDSKVVITTDESNRGGKVIETKRIVDDALRETPGVRHVLVYRKTNNPSVAFHAPRDLDWATEKKKYKTYYPCTPVDSEDPLFLLYTSGSTGAPKGVQHSTAGYLLGALLTMRYTFDTHQEDVFFTAGDIGWITGHTYVVYGPLLYGCATLVFEGTPAYPNYSRYWDIIDEHKVTQFYVAPTALRLLKRAGDSYIENHSLKSLRCLGSVGEPIAAEVWEWYSEKIGKNEIPIVDTYWQTESGSHLVTPLAGGVTPMKPGSASFPFFGIDAVVLDPNTGEELNTSHAEGVLAVKAAWPSFARTIWKNHDRYLDTYLNPYPGYYFTGDGAAKDKDGYIWILGRVDDVVNVSGHRLSTAEIEAAIIEDPIVAECAVVGFNDDLTGQAVAAFVVLKNKSSWSTATDDELQDIKKHLVFTVRKDIGPFAAPKLIILVDDLPKTRSGKIMRRILRKILAGESDQLGDVSTLSNPGIVRHLIDSVKL", "length": 713 }, "evidence": [ { "id": "F1NLR1", "url": "https://omabrowser.org/oma/group/F1NLR1/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q99NB1-1", "protein_name": "Acetyl-coenzyme A synthetase 2-like, mitochondrial", "gene_name": "Acss1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAARSLGSGVGRLLRGLQGRSGQSGWSLSVSRSTATRLPGCVPAAAQPGSYPALSAQAAQEPAAFWGPLARDTLVWDTPYHTVWDCDFRTGKIGWFLGGQLNVSVNCLDQHVQKSPETIALIWERDEPGTEVRITYRELLETTCRLANTLKRHGVHRGDRVAIYMPVSPLAVAAMLACARIGAIHTVVFAGFSAESLAGRINDAKCKAVITFNQGLRGGRVVELKKIVDEAVKSCPTVQHVLVAHRTDTKVPMGSLDIPLEQEMAKEAPVCTPESMSSEDMLFMLYTSGSTGTPKGLVHTQAGYLLYAAMTHKLVFDYQPGDVFGCVADIGWITGHSYVVYGPLCNGATTVLFESTPVYPDAGRYWETVQRLKINQFYGAPTAVRLLLKYGDAWVKKYDRSSLRTLGSVGEPINHEAWEWLHKVVGDGRCTLVDTWWQTETGGICIAPRPSEDGAEILPGMAMRPFFGIVPVLMDEKGNVLEGGDVSGALCISQAWPGMARTIYGDHQRFVDAYFRAYPGYYFTGDGAHRTEGGYYQITGRMDDVINISGHRLGTAEIEDAMADHPAVPETAVIGYPHDIKGEAAFAFIVLKDNISDENMVVNELKLSVATKIAKYAVPDQILVVKRLPKTRSGKVMRRLLRKIITSRGQDLGDTTTLEDPSVITEILSAFQKYEEQRAATN", "length": 682 }, "evidence": [ { "id": "F1NLR1", "url": "https://omabrowser.org/oma/group/F1NLR1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9NUB1-1", "protein_name": "Acetyl-coenzyme A synthetase 2-like, mitochondrial", "gene_name": "ACSS1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAARTLGRGVGRLLGSLRGLSGQPARPPCGVSAPRRAASGPSGSAPAVAAAAAQPGSYPALSAQAAREPAAFWGPLARDTLVWDTPYHTVWDCDFSTGKIGWFLGGQLNVSVNCLDQHVRKSPESVALIWERDEPGTEVRITYRELLETTCRLANTLKRHGVHRGDRVAIYMPVSPLAVAAMLACARIGAVHTVIFAGFSAESLAGRINDAKCKVVITFNQGLRGGRVVELKKIVDEAVKHCPTVQHVLVAHRTDNKVHMGDLDVPLEQEMAKEDPVCAPESMGSEDMLFMLYTSGSTGMPKGIVHTQAGYLLYAALTHKLVFDHQPGDIFGCVADIGWITGHSYVVYGPLCNGATSVLFESTPVYPNAGRYWETVERLKINQFYGAPTAVRLLLKYGDAWVKKYDRSSLRTLGSVGEPINCEAWEWLHRVVGDSRCTLVDTWWQTETGGICIAPRPSEEGAEILPAMAMRPFFGIVPVLMDEKGSVVEGSNVSGALCISQAWPGMARTIYGDHQRFVDAYFKAYPGYYFTGDGAYRTEGGYYQITGRMDDVINISGHRLGTAEIEDAIADHPAVPESAVIGYPHDIKGEAAFAFIVVKDSAGDSDVVVQELKSMVATKIAKYAVPDEILVVKRLPKTRSGKVMRRLLRKIITSEAQELGDTTTLEDPSIIAEILSVYQKCKDKQAAAK", "length": 689 }, "evidence": [ { "id": "F1NLR1", "url": "https://omabrowser.org/oma/group/F1NLR1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "F1NLR1", "url": "https://www.uniprot.org/uniprotkb/F1NLR1" } ], "pmid": "" }, { "name": "AMP binding", "id": "GO:0016208", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016208", "evidence": [ { "database": "UniProtKB", "id": "F1NLR1", "url": "https://www.uniprot.org/uniprotkb/F1NLR1" } ], "pmid": "" }, { "name": "acetate-CoA ligase activity", "id": "GO:0003987", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003987", "evidence": [ { "database": "UniProtKB", "id": "F1NLR1", "url": "https://www.uniprot.org/uniprotkb/F1NLR1" } ], "pmid": "" }, { "name": "propionate-CoA ligase activity", "id": "GO:0050218", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050218", "evidence": [ { "database": "UniProtKB", "id": "F1NLR1", "url": "https://www.uniprot.org/uniprotkb/F1NLR1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "F1NLR1", "url": "https://www.uniprot.org/uniprotkb/F1NLR1" } ], "pmid": "" }, { "name": "mitochondrial matrix", "id": "GO:0005759", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005759", "evidence": [ { "database": "UniProtKB", "id": "F1NLR1", "url": "https://www.uniprot.org/uniprotkb/F1NLR1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "lipid metabolic process", "id": "GO:0006629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006629", "evidence": [ { "database": "UniProtKB", "id": "F1NLR1", "url": "https://www.uniprot.org/uniprotkb/F1NLR1" } ], "pmid": "" }, { "name": "acetyl-CoA biosynthetic process", "id": "GO:0006085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006085", "evidence": [ { "database": "UniProtKB", "id": "F1NLR1", "url": "https://www.uniprot.org/uniprotkb/F1NLR1" } ], "pmid": "" }, { "name": "acetyl-CoA biosynthetic process from acetate", "id": "GO:0019427", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019427", "evidence": [ { "database": "UniProtKB", "id": "F1NLR1", "url": "https://www.uniprot.org/uniprotkb/F1NLR1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 233, "end_pos": 235, "annotation": "n_glycosylation_sequon" }, { "start_pos": 531, "end_pos": 533, "annotation": "n_glycosylation_sequon" }, { "start_pos": 86, "end_pos": 88, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "20373", "name": "", "equation": "propanoate + ATP + CoA = propanoyl-CoA + AMP + diphosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YE50-1", "A0A8V0XV06-1", "A0A8V0ZV64-1", "F1NLR1-1" ], "evidence": [ { "id": "20373", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/20373" } ] }, { "id": "23176", "name": "", "equation": "acetate + ATP + CoA = acetyl-CoA + AMP + diphosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YE50-1", "A0A8V0XV06-1", "A0A8V0ZV64-1", "F1NLR1-1" ], "evidence": [ { "id": "23176", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/23176" } ] }, { "id": "R-GGA-449911", "name": "acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [mitochondrial]", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "mitochondrial matrix", "input_participant_list": [ "R-ALL-29374" ], "output_participant_list": [ "R-ALL-159448" ], "enzyme_list": [ "F1NLR1-1" ], "evidence": [ { "id": "R-GGA-449911", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-449911" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-159448", "participant_name": "AMP [mitochondrial matrix]", "crossref": [ { "id": "ZINC000003860156", "database": "ZINC", "url": "" }, { "id": "C00020", "database": "COMPOUND", "url": "" }, { "id": "456215", "database": "ChEBI", "url": "" } ] }, { "participant_id": "R-ALL-29374", "participant_name": "CoA-SH [mitochondrial matrix]", "crossref": [ { "id": "57287", "database": "ChEBI", "url": "" }, { "id": "ZINC000008551087", "database": "ZINC", "url": "" }, { "id": "C00010", "database": "COMPOUND", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A0A8V0XV06", "gene_name": "ACSS1B", "activity": [ { "ec_number": "6.2.1.1", "activity": "acetate + ATP + CoA = acetyl-CoA + AMP + diphosphate.", "evidence": [ { "id": "A0A8V0XV06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XV06" } ] }, { "ec_number": "6.2.1.1", "activity": "", "evidence": [ { "id": "A0A8V0XV06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XV06" } ] } ] }, { "uniprot_ac": "A0A8V0YE50", "gene_name": "ACSS3", "activity": [ { "ec_number": "6.2.1.1", "activity": "acetate + ATP + CoA = acetyl-CoA + AMP + diphosphate.", "evidence": [ { "id": "A0A8V0YE50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE50" } ] }, { "ec_number": "6.2.1.17", "activity": "propanoate + ATP + CoA = propanoyl-CoA + AMP + diphosphate.", "evidence": [ { "id": "A0A8V0YE50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE50" } ] }, { "ec_number": "6.2.1.17", "activity": "", "evidence": [ { "id": "A0A8V0YE50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE50" } ] }, { "ec_number": "6.2.1.1", "activity": "", "evidence": [ { "id": "A0A8V0YE50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE50" } ] } ] }, { "uniprot_ac": "A0A8V0ZV64", "gene_name": "ACSS2", "activity": [ { "ec_number": "6.2.1.1", "activity": "acetate + ATP + CoA = acetyl-CoA + AMP + diphosphate.", "evidence": [ { "id": "A0A8V0ZV64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZV64" } ] }, { "ec_number": "6.2.1.17", "activity": "propanoate + ATP + CoA = propanoyl-CoA + AMP + diphosphate.", "evidence": [ { "id": "A0A8V0ZV64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZV64" } ] }, { "ec_number": "6.2.1.1", "activity": "", "evidence": [ { "id": "A0A8V0ZV64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZV64" } ] }, { "ec_number": "6.2.1.17", "activity": "", "evidence": [ { "id": "A0A8V0ZV64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZV64" } ] } ] }, { "uniprot_ac": "F1NLR1", "gene_name": "ACSS1A", "activity": [ { "ec_number": "6.2.1.1", "activity": "acetate + ATP + CoA = acetyl-CoA + AMP + diphosphate.", "evidence": [ { "id": "F1NLR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NLR1" } ] }, { "ec_number": "6.2.1.1", "activity": "", "evidence": [ { "id": "F1NLR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NLR1" } ] } ] } ], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1NLR1-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 665, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1NLR1-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1NLR1" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1NLR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NLR1" }, { "id": "PF13193", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13193" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "AMP-binding enzyme C-terminal", "eco_id": "ECO_0000259", "start_pos": 541, "end_pos": 619, "start_aa": "Glu", "end_aa": "Lys", "glycosite_overlap": "" }, { "evidence": [ { "id": "F1NLR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NLR1" }, { "id": "PF00501", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00501" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "AMP-dependent synthetase/ligase", "eco_id": "ECO_0000259", "start_pos": 93, "end_pos": 484, "start_aa": "Asp", "end_aa": "Ala", "glycosite_overlap": "" }, { "evidence": [ { "id": "F1NLR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NLR1" }, { "id": "PF16177", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16177" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Acetyl-coenzyme A synthetase N-terminal", "eco_id": "ECO_0000259", "start_pos": 35, "end_pos": 91, "start_aa": "Tyr", "end_aa": "Cys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "6.2.1.1", "ec_name": "acetate + ATP + CoA = acetyl-CoA + AMP + diphosphate.", "evidence": [ { "id": "6.2.1.1", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:6.2.1.1" }, { "id": "6.2.1.1", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=6.2.1.1" } ] } ], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 233, "end_pos": 235 }, { "start_pos": 531, "end_pos": 533 }, { "start_pos": 86, "end_pos": 88 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1NLR7-1", "uniprot_ac": "F1NLR7", "uniprot_id": "F1NLR7_CHICK", "mass": { "chemical_mass": 58764.0, "monoisotopic_mass": 58764.0 }, "refseq": { "ac": "NP_001012542", "name": "dual specificity protein kinase CLK3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012542" }, "gene_names": [ { "name": "CLK3", "type": "recommended", "evidence": [ { "id": "F1NLR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NLR7" } ] }, { "name": "CLK3", "type": "synonym", "evidence": [ { "id": "NP_001012542", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012542" } ] } ], "protein_names": [ { "name": "dual-specificity kinase", "type": "recommended", "evidence": [ { "id": "F1NLR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NLR7/entry#names_and_taxonomy" } ] }, { "name": "2.7.12.1", "type": "synonym", "evidence": [ { "id": "F1NLR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NLR7/entry#names_and_taxonomy" } ] }, { "name": "dual specificity protein kinase CLK3", "type": "synonym", "evidence": [ { "id": "NP_001012542", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012542" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: HAEK01046201.1, HAEL01008785.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA103992290, SAMEA103992432 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000245.1. On or before Dec 7, 2021 this sequence version replaced XP_015134285.1, NP_001012542.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001012542", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012542" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NLR7", "url": "https://www.uniprot.org/uniprotkb/F1NLR7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CLK3", "url": "https://www.uniprot.org/uniprotkb/F1NLR7", "locus": { "chromosome": "10", "start_pos": 2494598, "end_pos": 2509318, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021135", "url": "https://www.ensembl.org/id/ENSGALG00010021135" } ] } } ], "crossref": [ { "id": "F1NLR7", "url": "https://alphafold.ebi.ac.uk/entry/F1NLR7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000001362", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000001362", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd14214", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14214", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "415295", "url": "https://www.ncbi.nlm.nih.gov/gene/415295", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000719", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000719", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008271", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008271", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011009", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011009", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017441", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017441", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051175", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051175", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:415295", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:415295", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "IYAVCLM", "url": "https://omabrowser.org/oma/group/IYAVCLM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1NLR7", "url": "https://www.orthodb.org/?gene=F1NLR7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45646", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45646", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45646:SF10", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45646:SF10", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00069", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00069", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001012542", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012542", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "10596", "url": "https://www.rhea-db.org/rhea/10596", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "17989", "url": "https://www.rhea-db.org/rhea/17989", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "46608", "url": "https://www.rhea-db.org/rhea/46608", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "F1NLR7", "url": "https://www.uniprot.org/uniprotkb/F1NLR7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NLR7-1", "url": "https://www.uniprot.org/uniprotkb/F1NLR7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MHHCKRYRSPEQEACWGPRWKRKRSRSRAYEGRPRCPPRRDLPRRSRSRSHDRMPYHRRYRDRRDSDAYRFEERSPSFDDDYYSTRTRHWRRSRDREQYYDRKHQHYCRKRRTRSCSSASSRSQQSSKRSRSVEDDKEGHLVCRIGDWLQERYEIVGSLGEGTFGKVVECVDHARGKSQVALKIIKNVGKYREAARLEINVLKKIKEKDKENKFLCVLMSDWFNFHGHMCIAFELLGKNTFEFLKENNFQPYPLPQIRHMAYQLCHALKFLHDNQLTHTDLKPENILFVNSDFDTLYNEKKSCEEKSIRNTSIRVADFGSATFDHEHHTTIVATRHYRPPEVILELGWAQPCDVWSTGCILFEYYRGFTLFQTHENREHLVMMEKILGPIPSHMIHRTRKQKYFYKGNLVWDENTSDGRYVQENCKPLRTYMLHDSLEHAQLFDLIRRMLEFDPSRRITFSEALLHPFFAGLSAEERMLCGRGTSRDLSR", "length": 490, "header": "tr|F1NLR7-1|F1NLR7_CHICK Isoform 1 of dual-specificity kinase OS=Gallus gallus OX=9031 GN=CLK3 PE=3 SV=1 CANONICAL=F1NLR7-1" }, "isoforms": [ { "isoform_ac": "F1NLR7-1", "url": "https://www.uniprot.org/uniprotkb/F1NLR7/entry#F1NLR7-1", "sequence": { "sequence": "MHHCKRYRSPEQEACWGPRWKRKRSRSRAYEGRPRCPPRRDLPRRSRSRSHDRMPYHRRYRDRRDSDAYRFEERSPSFDDDYYSTRTRHWRRSRDREQYYDRKHQHYCRKRRTRSCSSASSRSQQSSKRSRSVEDDKEGHLVCRIGDWLQERYEIVGSLGEGTFGKVVECVDHARGKSQVALKIIKNVGKYREAARLEINVLKKIKEKDKENKFLCVLMSDWFNFHGHMCIAFELLGKNTFEFLKENNFQPYPLPQIRHMAYQLCHALKFLHDNQLTHTDLKPENILFVNSDFDTLYNEKKSCEEKSIRNTSIRVADFGSATFDHEHHTTIVATRHYRPPEVILELGWAQPCDVWSTGCILFEYYRGFTLFQTHENREHLVMMEKILGPIPSHMIHRTRKQKYFYKGNLVWDENTSDGRYVQENCKPLRTYMLHDSLEHAQLFDLIRRMLEFDPSRRITFSEALLHPFFAGLSAEERMLCGRGTSRDLSR", "length": 490, "header": "tr|F1NLR7-1|F1NLR7_CHICK Isoform 1 of dual-specificity kinase OS=Gallus gallus OX=9031 GN=CLK3 PE=3 SV=1 CANONICAL=F1NLR7-1" }, "locus": { "chromosome": "10", "start_pos": 2509044, "end_pos": 2501101, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051180.1", "url": "https://www.ensembl.org/id/ENSGALT00010051180.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030371.1", "url": "https://www.ensembl.org/id/ENSGALP00010030371.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "gga:415295", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:415295", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287B9K6-1", "protein_name": "dual-specificity kinase", "gene_name": "CLK3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MHHCKRYRSPEPDPYLSYRWKRRRSYSREHEGRLRYPSRREPPPRRSRSRSHDRLPYQRRYREHRDSDTYRCEERSPSFGEDCYGSSRSHHRRRSREREPYRTRKHAHHCHKRRTRSCSSASSRSQQSSKRSSRSVEDDKEGHLVCRIGDWLQERCTATFHEIVGNLGEGTFGKVVECLDHARGKSQVALKIIRNVGKYREAARLEINVLKKIKEKDKENKFLCVLMSDWFNFHGHMCIAFELLGKNTFEFLKENNFQPYPLPHVRHMAYQLCHALRFLHENQLTHTDLKPENILFVNSEFETLYNEHKSCEEKSVKNTSIRVADFGSATFDHEHHTTIVATRHYRPPEVILELGWAQPCDVWSIGCILFEYYRGFTLFQTHENREHLVMMEKILGPIPSHMIHRTRKQKYFYKGGLVWDENSSDGRYVKENCKPLKSYMLQDSLEHVQLFDLMRKMLEFDPAQRITLAEALLHPFFAGLTPEERSFHTSRNPSR", "length": 495 }, "evidence": [ { "id": "F1NLR7", "url": "https://omabrowser.org/oma/group/F1NLR7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3HEH4-1", "protein_name": "dual-specificity kinase", "gene_name": "Clk3", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MHHCKRYRSPEPDPYLSYRWKRRRSYSREHEGRLRYPSRREPPPRRSRSRSHDRLPYPRRYREHRDSDTYRCEERSPSFGEDCYGSSRSRHRRRSRERGPYRTRKHAHHCHKRRTRSCSSASSRSQQSSKRSSRSVEDDKEGHLVCRIGDWLQERYEIVGNLGEGTFGKVVECLDHARGKSQVALKIIRNVGKYREAARLEINVLKKIKEKDKENKFLCVLMSDWFNFHGHMCIAFELLGKNTFEFLKENNFQPYPLPHVRHMAYQLCHALRFLHENQLTHTDLKPENILFVNSEFETLYNEHKSCEEKSVKNTSIRVADFGSATFDHEHHTTIVATRHYRPPEVILELGWAQPCDVWSIGCILFEYYRGFTLFQTHENREHLVMMEKILGPIPSHMIHRTRKQKYFYKGGLVWDENSSDGRYVKENCKPLKSYMLQDSLEHVQLFDLMRRMLEFDPAQRITLAEALLHPFFAGLTPEERSFHSSRNPSR", "length": 490 }, "evidence": [ { "id": "F1NLR7", "url": "https://omabrowser.org/oma/group/F1NLR7/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "O35492-1", "protein_name": "Dual specificity protein kinase CLK3", "gene_name": "Clk3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MHHCKRYRSPEPDPYLSYRWKRRRSYSREHEGRLRYPSRREPPPRRSRSRSHDRIPYQRRYREHRDSDTYRCEERSPSFGEDCYGSSRSRHRRRSRERAPYRTRKHAHHCHKRRTRSCSSASSRSQQSSKRSSRSVEDDKEGHLVCRIGDWLQERYEIVGNLGEGTFGKVVECLDHARGKSQVALKIIRNVGKYREAARLEINVLKKIKEKDKENKFLCVLMSDWFNFHGHMCIAFELLGKNTFEFLKENNFQPYPLPHVRHMAYQLCHALRFLHENQLTHTDLKPENILFVNSEFETLYNEHKSCEEKSVKNTSIRVADFGSATFDHEHHTTIVATRHYRPPEVILELGWAQPCDVWSIGCILFEYYRGFTLFQTHENREHLVMMEKILGPIPSHMIHRTRKQKYFYKGGLVWDENSSDGRYVKENCKPLKSYMLQDSLEHVQLFDLMRRMLEFDPAQRITLAEALLHPFFAGLTPEERSFHSSRNPSR", "length": 490 }, "evidence": [ { "id": "F1NLR7", "url": "https://omabrowser.org/oma/group/F1NLR7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P49761-1", "protein_name": "Dual specificity protein kinase CLK3", "gene_name": "CLK3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MHHCKRYRSPEPDPYLSYRWKRRRSYSREHEGRLRYPSRREPPPRRSRSRSHDRLPYQRRYRERRDSDTYRCEERSPSFGEDYYGPSRSRHRRRSRERGPYRTRKHAHHCHKRRTRSCSSASSRSQQSSKRSSRSVEDDKEGHLVCRIGDWLQERYEIVGNLGEGTFGKVVECLDHARGKSQVALKIIRNVGKYREAARLEINVLKKIKEKDKENKFLCVLMSDWFNFHGHMCIAFELLGKNTFEFLKENNFQPYPLPHVRHMAYQLCHALRFLHENQLTHTDLKPENILFVNSEFETLYNEHKSCEEKSVKNTSIRVADFGSATFDHEHHTTIVATRHYRPPEVILELGWAQPCDVWSIGCILFEYYRGFTLFQTHENREHLVMMEKILGPIPSHMIHRTRKQKYFYKGGLVWDENSSDGRYVKENCKPLKSYMLQDSLEHVQLFDLMRRMLEFDPAQRITLAEALLHPFFAGLTPEERSFHTSRNPSR", "length": 490 }, "evidence": [ { "id": "F1NLR7", "url": "https://omabrowser.org/oma/group/F1NLR7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q3SX21-1", "protein_name": "Dual specificity protein kinase CLK3", "gene_name": "CLK3", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MHHCKRYRSPEPDPYLSYRWKRRRSYSREHEGRLRYPSRREPPPRRSRSRSHDRLPYQRRYREHRDSDTYRCEDRSPSFGEDYYGSSRCHHRRRSREREPYRTRKHAHHCHKRRTRSCSSASSRSQQSSKRSSRSVEDDKEGHLVCRIGDWLQERYEIVGNLGEGTFGKVVECLDHARGKSQVALKIIRNVGKYREAARLEINVLKKIKEKDKENKFLCVLMSDWFNFHGHMCIAFELLGKNTFEFLKENNFQPYPLPHVRHMAYQLCHALRFLHENQLTHTDLKPENILFVNSEFETLYNEHKSCEEKSVKNTSIRVADFGSATFDHEHHTTIVATRHYRPPEVILELGWAQPCDVWSIGCILFEYYRGFTLFQTHENREHLVMMEKILGPIPSHMIHRTRKQKYFYKGGLVWDENSSDGRYVKENCKPLKSYMLQDTLEHVQLFDLMRRMLEFDPAQRITLAEALLHPFFAGLTPEERSFHTSRNPSR", "length": 490 }, "evidence": [ { "id": "F1NLR7", "url": "https://omabrowser.org/oma/group/F1NLR7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q63117-1", "protein_name": "Dual specificity protein kinase CLK3", "gene_name": "Clk3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MHHCKRYRSPEPDPYLSYRWKRRRSYSREHEGRLRYPSRREPPPRRSRSRSHDRIPYQRRYREHRDSDTYRCEERSPSFGEDCYGSSRSRHRRRSRERGPYRTRKHAHHCHKRRTRSCSSASSRSQQSSKRSSRSVEDDKEGHLVCRIGDWLQERYEIVGNLGEGTFGKVVECLDHARGKSQVALKIIRNVGKYREAARLEINVLKKIKEKDKENKFLCVLMSDWFNFHGHMCIAFELLGKNTFEFLKENNFQPYPLPHVRHMAYQLCHALRFLHENQLTHTDLKPENILFVNSEFETLYNEHKSCEEKSVKNTSIRVADFGSATFDHEHHTTIVATRHYRPPEVILELGWAQPCDVWSIGCILFEYYRGFTLFQTHENREHLVMMEKILGPIPSHMIHRTRKQKYFYKGGLVWDENSSDGRYVKENCKPLKSYMLQDSLEHVQLFDLMRRMLEFDPAQRITLAEALLHPFFAGLTPEERSFHSSRNPSR", "length": 490 }, "evidence": [ { "id": "F1NLR7", "url": "https://omabrowser.org/oma/group/F1NLR7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "F1NLR7", "url": "https://www.uniprot.org/uniprotkb/F1NLR7" } ], "pmid": "" }, { "name": "protein tyrosine kinase activity", "id": "GO:0004713", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004713", "evidence": [ { "database": "UniProtKB", "id": "F1NLR7", "url": "https://www.uniprot.org/uniprotkb/F1NLR7" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "F1NLR7", "url": "https://www.uniprot.org/uniprotkb/F1NLR7" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "F1NLR7", "url": "https://www.uniprot.org/uniprotkb/F1NLR7" } ], "pmid": "" }, { "name": "protein serine/threonine/tyrosine kinase activity", "id": "GO:0004712", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004712", "evidence": [ { "database": "UniProtKB", "id": "F1NLR7", "url": "https://www.uniprot.org/uniprotkb/F1NLR7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1NLR7", "url": "https://www.uniprot.org/uniprotkb/F1NLR7" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "F1NLR7", "url": "https://www.uniprot.org/uniprotkb/F1NLR7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "regulation of RNA splicing", "id": "GO:0043484", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043484", "evidence": [ { "database": "UniProtKB", "id": "F1NLR7", "url": "https://www.uniprot.org/uniprotkb/F1NLR7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 310, "end_pos": 312, "annotation": "n_glycosylation_sequon" }, { "start_pos": 414, "end_pos": 416, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "10596", "name": "", "equation": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V1ADF0-1", "F1N9Y5-1", "A0A8V0XQG0-1", "A0A8V0Y9A0-1", "A0A8V1AFM7-1", "A0A8V0Z0R8-1", "A0A8V0Z4B2-1", "A0A8V0ZBN6-1", "P09324-1", "A0A8V0XHW1-1", "A0A8V0YW12-1", "A0A8V0YUJ4-1", "A0A8V0ZSN8-1", "F1NVF2-1", "A0A8V1AKW4-1", "A0A8V0XB17-1", "A0A8V0ZC34-1", "A0A8V0YYC1-1", "A0A8V0ZND5-1", "A0A8V1ACF7-1", "A0A8V0ZP30-1", "E1BTE1-1", "Q07497-1", "A0A8V0X6E7-1", "F1NCL8-1", "A0A8V0XNF4-1", "A0A8V0XN86-1", "A0A8V0YEV0-1", "A0A8V0XQ80-1", "A0A8V0XZ82-1", "A0A8V0YZE5-1", "A0A8V0YYZ7-1", "A0A8V0YCV8-1", "A0A8V0YGR1-1", "A0A8V0YNY4-1", "A0A8V0YXM5-1", "A0A8V0YXZ9-1", "A0A3Q2UKD3-1", "A0A8V0YIT6-1", "A0A8V0YIV6-1", "R4GJW5-1", "A0A8V1A3N1-1", "A0A8V1A9R2-1", "A0A8V0ZE65-1", "A0A8V0ZER1-1", "A0A8V0ZXS7-1", "A0A8V1A7N1-1", "H9KZZ1-1", "F1NQL9-1", "A0A8V1ABP4-1", "F1NZY8-1", "Q02977-1", "A0A1D5PD64-1", "A0A8V0ZDU6-1", "A0A3Q2U1T2-1", "R4GJB8-1", "A0A3Q2U639-1", "A0A8V0X5W9-1", "E1C7Z1-1", "A0A8V0Y7Y3-1", "Q5ZIU3-1", "A0A8V0YPR4-1", "A0A8V0YT43-1", "A0A8V0Z3S3-1", "A0A8V0YJJ1-1", "A0A8V0YKP8-1", "A0A8V0YZ74-1", "A0A8V0ZWV8-1", "A0A8V1A069-1", "A0A8V1A7E0-1", "A0A8V1AEL3-1", "E1BTT3-1", "F1N996-1", "H9KZZ2-1", "E1C2C8-1", "Q05876-1", "Q90891-1", "O42422-1", "P00523-1", "P08941-1", "P13387-1", "P18460-1", "P18461-1", "P21804-1", "P28693-1", "P29318-1", "P42683-1", "P54755-1", "Q00944-1", "Q07494-1", "Q07496-1", "Q07498-1", "Q08156-1", "Q6XUX0-1", "Q75R65-1", "Q8AXY6-1", "Q8JH64-1", "Q8QHL3-1", "Q91009-1", "Q91044-1", "Q91987-1", "Q98949-1", "Q9PUF6-1", "F1NW21-1", "A0A8V0YLC3-1", "A0A8V0Z7L6-1", "F1NJX6-1", "A0A8V0YUC4-1", "F1NUX4-1", "A0A8V1A2E6-1", "E1BX69-1", "A0A8V0XPF0-1", "A0A8V0XFC9-1", "A0A8V0XBZ6-1", "A0A8V0ZRU7-1", "A0A8V0ZXD3-1", "A0A8V0YYI3-1", "A0A8V0YWW2-1", "A0A8V0YZP9-1", "A0A8V0YRJ8-1", "F1NLR7-1", "A0A8V0XCY6-1", "A0A8V1AMK9-1", "A0A8V0Z189-1", "P41239-1" ], "evidence": [ { "id": "10596", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/10596" } ] }, { "id": "17989", "name": "", "equation": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q6U1I9-1", "A0A8V0XNJ2-1", "A0A8V0ZUL0-1", "A0A8V0ZT63-1", "A0A8V1ACW2-1", "A0A8V0Z1X0-1", "A0A8V0YHN2-1", "A0A8V0YMN5-1", "A0A8V0Z807-1", "A0A8V0Z930-1", "A0A8V0YFR6-1", "A0A1D5P0M9-1", "A0A8V0ZBN6-1", "A0A3Q2U9U9-1", "A0A8V0YXZ5-1", "A0A8V0ZSP4-1", "A0A8V0ZXQ9-1", "A0A8V0ZZV3-1", "A0A8V1ADF0-1", "A0A8V0ZFT3-1", "A0A8V0ZA45-1", "A0A8V0ZB33-1", "A0A8V0ZD70-1", "A0A8V0Z8T4-1", "R4GIN8-1", "A0A8V0ZK64-1", "A0A8V0ZC16-1", "A0A8V0ZWW1-1", "E1BY69-1", "A0A8V0ZDW9-1", "A0A8V0ZKA2-1", "A0A3Q3B2F1-1", "F1P356-1", "A0A8V1AHA8-1", "Q8QFP8-1", "F1P011-1", "A0A8V0YKK3-1", "A0A1D5NWT4-1", "A0A1D5PMQ7-1", "E1BWA3-1", "F1NVF2-1", "A0A1D5PXN4-1", "A0A3Q2TY19-1", "A0A3Q2U592-1", "A0A8V0XCV5-1", "A0A1D5P8A9-1", "A0A1D5PMG2-1", "A0A8V0X1Q7-1", "A0A8V0Y935-1", "A0A8V0YM96-1", "A0A8V0YF83-1", "A0A8V0YJP9-1", "A0A8V1AKW4-1", "A0A8V0ZSB4-1", "F1NBT0-1", "P18652-1", "P21868-1", "P21869-1", "P53666-1", "P79996-1", "Q5F3W3-1", "Q5ZJS0-1", "Q5ZKN1-1", "Q5ZLL1-1", "A0A8V0XCS0-1", "A0A8V0XNK8-1", "A0A8V0XLV6-1", "A0A8V0XDR5-1", "E1BYH2-1", "E1BQN6-1", "A0A8V0XU71-1", "Q5ZJH6-1", "A0A8V0Y3D1-1", "A0A8V0Y7C3-1", "A0A8V0YCY4-1", "A0A8V0YIV6-1", "A0A8V0YK18-1", "A0A8V0YM22-1", "A0A8V0YTN5-1", "A0A8V0YTP2-1", "Q5F3L1-1", "A0A8V0Y3L2-1", "A0A8V0YCY8-1", "A0A8V0Y9Q1-1", "A0A8V0ZD48-1", "A0A8V0ZD60-1", "A0A8V0ZBZ2-1", "A0A8V0Z9J0-1", "A0A8V1ABF3-1", "Q8AYC9-1", "A0A8V0Z927-1", "A0A8V1A2T9-1", "Q5ZKI0-1", "Q7T0B1-1", "P10741-1", "A0A8V0YFH4-1", "E1C848-1", "A0A8V0X8M1-1", "E1BW33-1", "A0A8V0Z283-1", "A0A8V0Z157-1", "A0A3Q2U4X3-1", "A0A8V0XW11-1", "E1BUG0-1", "A0A8V1ABP4-1", "A0A8V1AJA4-1", "A0A8V1AEH4-1", "F1NJH1-1", "A0A8V1AMK5-1", "A0A3Q2TRY2-1", "A0A8V0X3D6-1", "A0A1D5PD64-1", "A0A8V0XQ97-1", "R4GJB8-1", "A0A8V0X5Z8-1", "A0A8V0XG21-1", "A0A8V0XB58-1", "A0A8V0XMX8-1", "A0A8V0XQS0-1", "A0A8V0XW29-1", "A0A8V0Y074-1", "A0A8V0XXB8-1", "A0A8V0XQ14-1", "A0A8V0XMT1-1", "A0A8V0Y457-1", "A0A8V0Y823-1", "A0A8V0Y4L8-1", "A0A8V0XND6-1", "A0A8V0YZ74-1", "A0A8V0YTI1-1", "A0A8V0YLV1-1", "A0A8V0Z2E3-1", "A0A8V0YCV9-1", "A0A8V0YSH3-1", "A0A8V0YYX2-1", "A0A8V0YZY4-1", "Q5ZIU3-1", "A0A8V0YZK0-1", "A0A8V0ZKM9-1", "A0A8V0ZWC7-1", "A0A8V1A1Y7-1", "A0A8V1A069-1", "A0A8V0ZI32-1", "A0A8V0ZH91-1", "E1BQV7-1", "A0A8V0ZRX1-1", "A0A8V0ZUU9-1", "A0A8V1A0Y8-1", "A0A8V1A7E9-1", "A0A8V1A7E0-1", "A0A8V1A3T8-1", "A0A8V1A9S5-1", "A0A8V1A7M0-1", "A0A8V1A675-1", "A0A8V1A1P3-1", "A0A8V1ADT4-1", "E1BWT0-1", "A0A8V1ACF6-1", "A0A8V1ADN9-1", "A0A8V1AM12-1", "A0A8V1A4Q4-1", "Q90891-1", "A0A1D5P517-1", "F1NB57-1", "F1NUX4-1", "A0A8V0ZZE4-1", "P05625-1", "P13863-1", "P67962-1", "Q04982-2", "Q0GGW5-1", "Q6XUX0-1", "Q8QGX4-1", "Q9I9E0-1", "Q9IA88-1", "Q5ZJK4-1", "A0A1D5PTJ8-1", "E1C2I2-1", "F1NCX7-1", "F1NKW3-1", "A0A8V1A0W4-1", "A0A8V1A4J8-1", "A0A8V1ACK0-1", "F1NCY7-1", "A0A8V0X6T4-1", "A0A8V0ZFM2-1", "A0A8V0XUM6-1", "A0A8V0XEA3-1", "A0A8V1AIY7-1", "A0A8V0YHH2-1", "A0A3Q2UI52-1", "A0A8V0ZZK5-1", "A0A8V0ZPX2-1", "A0A8V1ACB5-1", "A0A8V0YDH4-1", "A0A8V1AFS4-1", "A0A8V1AH12-1", "A0A8V0YRC9-1", "A0A8V0ZQT5-1", "A0A8V0ZFP1-1", "E1C764-1", "A0A1D5PUY5-1", "F1P4G3-1", "A0A8V0ZMK1-1", "A0A8V0Y2I5-1", "A0A8V0ZLU3-1", "A0A8V0ZNP7-1", "A0A8V0Z2Z3-1", "A0A8V0YNI5-1", "Q90771-1", "A0A8V0X4P0-1", "A0A8V0X7R2-1", "A0A3Q3A664-1", "A0A8V0YGW2-1", "E1C581-1", "A0A8V1AC40-1", "A0A3Q2TUS7-1", "A0A1D5PA08-1", "A0A8V0XFW1-1", "A0A8V0XAH9-1", "A0A8V1A4A1-1", "A0A8V0ZD40-1", "A0A8V0Z6T1-1", "A0A8V1A4V7-1", "E1C093-1", "A0A8V0YZF2-1", "E1BX69-1", "A0A8V0XI18-1", "A0A8V0Y955-1", "A0A1D5PB73-1", "A0A1D5PV76-1", "A0A1D5PX90-1", "A0A1L1RWI9-1", "A0A3Q2TV19-1", "A0A3Q2UF44-1", "A0A8V0X4Q3-1", "A0A8V0Z124-1", "A0A8V0Z6K4-1", "A0A8V1AE45-1", "A0A8V0YZV9-1", "A0A8V0YYZ3-1", "A0A8V0ZUC6-1", "A0A8V0ZUU8-1", "A0A8V1AG70-1", "F1NA68-1", "F1NLR7-1", "A0A8V0Y6K1-1", "A0A8V0XS42-1", "A0A8V0YRN4-1", "A0A8V0YFP8-1", "A0A8V1A7P9-1", "A0A1D5PRN8-1", "A0A3Q3AAD7-1", "A0A3Q2TWZ8-1", "A0A8V0XBZ0-1", "A0A8V0XFX2-1", "A0A8V0YFL1-1", "A0A8V0YTL9-1", "A0A8V0YMB3-1", "A0A8V0X2Y2-1", "A0A8V0XCY6-1", "A0A3Q2UI62-1", "A0A8V0Y241-1", "A0A8V0Z8G2-1", "A0A8V1ABR8-1", "A0A8V1AP60-1", "A0A8V0YZM1-1", "A0A8V0ZB38-1", "A0A8V0Z466-1", "A0A8V0ZA06-1", "A0A8V1AMQ2-1", "A0A8V0ZGY3-1", "A0A8V0ZQJ2-1", "A0A8V0ZYU6-1", "A0A8V1A513-1", "A0A8V0XE48-1", "A0A8V0XQQ4-1", "A0A8V0XKG0-1" ], "evidence": [ { "id": "17989", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/17989" } ] }, { "id": "46608", "name": "", "equation": "L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": 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"Q5ZKN1-1", "Q5ZLL1-1", "A0A8V0XCS0-1", "A0A8V0XNK8-1", "A0A8V0XLV6-1", "A0A8V0XDR5-1", "E1BYH2-1", "F1NB57-1", "E1BQN6-1", "A0A8V0XU71-1", "Q5ZJH6-1", "A0A8V0Y3D1-1", "A0A8V0Y7C3-1", "A0A8V0YCY4-1", "A0A8V0YIV6-1", "A0A8V0YK18-1", "A0A8V0YM22-1", "A0A8V0YTN5-1", "A0A8V0YTP2-1", "Q5F3L1-1", "A0A8V0XU96-1", "E1C6T4-1", "A0A8V0Y3L2-1", "A0A8V0YCY8-1", "A0A8V0Y9Q1-1", "A0A8V0ZD48-1", "A0A8V0ZD60-1", "A0A8V0ZBZ2-1", "A0A8V0Z9J0-1", "A0A8V1ABF3-1", "Q8AYC9-1", "A0A8V0Z927-1", "A0A8V1A2T9-1", "Q5ZKI0-1", "Q7T0B1-1", "P10741-1", "A0A8V1AMK5-1", "P67962-1", "A0A8V0YFH4-1", "E1C848-1", "A0A8V0X8M1-1", "E1BW33-1", "A0A8V0Z283-1", "A0A8V0Z157-1", "A0A3Q2U4X3-1", "A0A8V0XW11-1", "E1BUG0-1", "A0A8V1ABP4-1", "A0A8V1AJA4-1", "A0A8V1AEH4-1", "F1NJH1-1", "A0A3Q2TRY2-1", "A0A8V0X3D6-1", "A0A1D5PD64-1", "A0A8V0XQ97-1", "R4GJB8-1", "A0A8V0X5Z8-1", "A0A8V0XG21-1", "A0A8V0XB58-1", "A0A8V0XMX8-1", "A0A8V0XQS0-1", "A0A8V0XW29-1", "A0A8V0Y074-1", "A0A8V0XXB8-1", "A0A8V0XQ14-1", "A0A8V0XI18-1", "A0A8V0XMT1-1", "A0A8V0Y457-1", "A0A8V0Y823-1", "A0A8V0Y4L8-1", "A0A8V0XND6-1", "A0A8V0Y8X9-1", "A0A8V0YZ74-1", "A0A8V0YTI1-1", "A0A8V0YLV1-1", "A0A8V0Z2E3-1", "A0A8V0YCV9-1", "A0A8V0YSH3-1", "A0A8V0YYX2-1", "A0A8V0YZY4-1", "Q5ZIU3-1", "A0A8V0YZK0-1", "A0A8V0ZKM9-1", "A0A8V0ZWC7-1", "A0A8V1A1Y7-1", "A0A8V1A069-1", "A0A8V0ZI32-1", "A0A8V0ZH91-1", "E1BQV7-1", "A0A8V0ZRX1-1", "A0A8V0ZUU9-1", "A0A8V1A0Y8-1", "A0A8V1A7E9-1", "A0A8V1A7E0-1", "A0A8V1A3T8-1", "A0A8V1A9S5-1", "A0A8V1A7M0-1", "A0A8V1A675-1", "A0A8V1A1P3-1", "A0A8V1ADT4-1", "E1BWT0-1", "A0A8V1ACF6-1", "A0A8V1ADN9-1", "A0A8V1AM12-1", "A0A8V1A4Q4-1", "Q90891-1", "F1NUX4-1", "A0A8V0ZZE4-1", "P05625-1", "P13863-1", "Q04982-2", "Q0GGW5-1", "Q6XUX0-1", "Q8QGX4-1", "Q9I9E0-1", "Q9IA88-1", "Q5ZJK4-1", "A0A1D5PTJ8-1", "E1C2I2-1", "F1NCX7-1", "F1NKW3-1", "A0A8V1A0W4-1", "A0A8V1A4J8-1", "A0A8V1ACK0-1", "F1NCY7-1", "A0A8V0X6T4-1", "A0A8V0XUM6-1", "A0A8V0XEA3-1", "A0A8V0YHH2-1", "A0A3Q2UI52-1", "A0A8V0ZZK5-1", "A0A8V0ZPX2-1", "A0A8V1ACB5-1", "A0A8V0YDH4-1", "A0A8V1AFS4-1", "A0A8V1AH12-1", "A0A8V0ZQT5-1", "A0A8V0ZFP1-1", "E1C764-1", "F1P4G3-1", "A0A8V0Y2I5-1", "A0A8V0ZLU3-1", "A0A8V0ZNP7-1", "A0A8V0Z2Z3-1", "A0A8V0YNI5-1", "Q90771-1", "A0A8V0X4P0-1", "A0A8V0X7R2-1", "A0A3Q3A664-1", "A0A8V0YGW2-1", "E1C581-1", "A0A8V1AC40-1", "A0A3Q2TUS7-1", "A0A1D5PA08-1", "A0A8V0XFW1-1", "A0A8V0XAH9-1", "A0A8V0ZFM2-1", "A0A8V1A4A1-1", "A0A8V0ZD40-1", "A0A8V0Z6T1-1", "A0A8V1A4V7-1", "A0A8V0YZF2-1", "E1BX69-1", "A0A8V0Y955-1", "A0A1D5PB73-1", "A0A1D5PV76-1", "A0A1D5PX90-1", "A0A1L1RWI9-1", "A0A3Q2TV19-1", "A0A3Q2UF44-1", "A0A8V0X4Q3-1", "A0A8V0Z124-1", "A0A8V0Z6K4-1", "A0A8V1AIY7-1", "A0A8V1AE45-1", "A0A8V0YZV9-1", "A0A8V0YYZ3-1", "A0A8V0ZUC6-1", "A0A8V0ZUU8-1", "A0A8V1AG70-1", "F1NA68-1", "F1NLR7-1", "A0A8V0Y6K1-1", "A0A8V0XS42-1", "A0A8V0YRN4-1", "A0A8V0YFP8-1", "A0A8V1A7P9-1", "A0A1D5PRN8-1", "A0A3Q3AAD7-1", "A0A3Q2TWZ8-1", "A0A8V0XBZ0-1", "A0A8V0XFX2-1", "A0A8V0YFL1-1", "A0A8V0YTL9-1", "A0A8V0YMB3-1", "A0A8V0X2Y2-1", "A0A8V0XCY6-1", "A0A3Q2UI62-1", "A0A8V0Y241-1", "A0A8V0Z8G2-1", "A0A8V1ABR8-1", "A0A8V1AP60-1", "A0A8V0YZM1-1", "A0A8V0ZB38-1", "A0A8V0Z466-1", "A0A8V0ZA06-1", "A0A8V1AMQ2-1", "A0A8V0ZGY3-1", "A0A8V0ZQJ2-1", "A0A8V0ZYU6-1", "A0A8V1A513-1", "A0A8V0XE48-1", "A0A8V0XKG0-1" ], "evidence": [ { "id": "46608", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/46608" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A1D5NWT4", "gene_name": "RPS6KA3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5NWT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NWT4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A1D5NWT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NWT4" } ] } ] }, { "uniprot_ac": "A0A1D5P0M9", "gene_name": "MAP3K13", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5P0M9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P0M9" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A1D5P0M9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P0M9" } ] } ] }, { "uniprot_ac": "A0A1D5P517", "gene_name": "PLK3", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5P517", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P517" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0A1D5P517", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P517" } ] } ] }, { "uniprot_ac": "A0A1D5P8A9", "gene_name": "SNRK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5P8A9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P8A9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A1D5P8A9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P8A9" } ] } ] }, { "uniprot_ac": "A0A1D5PA08", "gene_name": "STK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PA08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PA08" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A1D5PA08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PA08" } ] } ] }, { "uniprot_ac": "A0A1D5PB73", "gene_name": "CASK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PB73", "database": "UniProtKB", "url": 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"activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XBZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XBZ0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XBZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XBZ0" } ] } ] }, { "uniprot_ac": "A0A8V0XBZ6", "gene_name": "EPHA7", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XBZ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XBZ6" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0XBZ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XBZ6" } ] } ] }, { "uniprot_ac": "A0A8V0XCS0", "gene_name": "PRKG2", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XCS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCS0" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "A0A8V0XCS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCS0" } ] } ] }, { "uniprot_ac": "A0A8V0XCV5", "gene_name": "MAP3K7", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XCV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCV5" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0XCV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCV5" } ] } ] }, { "uniprot_ac": "A0A8V0XCY6", "gene_name": "TTK", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP 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} ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0XFC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XFC9" } ] } ] }, { "uniprot_ac": "A0A8V0XFW1", "gene_name": "SGK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XFW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XFW1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XFW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XFW1" } ] } ] }, { "uniprot_ac": "A0A8V0XFX2", "gene_name": "NEK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XFX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XFX2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XFX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XFX2" } ] } ] }, { "uniprot_ac": "A0A8V0XG21", "gene_name": "LOC107050335", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XG21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XG21" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XG21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XG21" } ] } ] }, { "uniprot_ac": "A0A8V0XHW1", "gene_name": "LYN", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XHW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XHW1" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0XHW1", "database": "UniProtKB", "url": 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"uniprot_ac": "A0A8V0XLV6", "gene_name": "MAPK10", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XLV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XLV6" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0XLV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XLV6" } ] } ] }, { "uniprot_ac": "A0A8V0XMT1", "gene_name": "MOS", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XMT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMT1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XMT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMT1" } ] } ] }, { "uniprot_ac": "A0A8V0XMX8", "gene_name": "MASTL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XMX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMX8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XMX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMX8" } ] } ] }, { "uniprot_ac": "A0A8V0XN86", "gene_name": "MUSK", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XN86", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XN86" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0XN86", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XN86" } ] } ] }, { "uniprot_ac": "A0A8V0XND6", "gene_name": "RIOK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XND6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XND6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XND6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XND6" } ] } ] }, { "uniprot_ac": "A0A8V0XNF4", "gene_name": "EGFR", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XNF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNF4" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0XNF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNF4" } ] } ] }, { "uniprot_ac": "A0A8V0XNJ2", "gene_name": "CDK8", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XNJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNJ2" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XNJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNJ2" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0XNJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNJ2" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A8V0XNJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNJ2" } ] } ] }, { "uniprot_ac": "A0A8V0XNK8", "gene_name": "PRKCQ", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XNK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNK8" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V0XNK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNK8" } ] } ] }, { "uniprot_ac": "A0A8V0XPF0", "gene_name": "EPHA6", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XPF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XPF0" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0XPF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XPF0" } ] } ] }, { "uniprot_ac": "A0A8V0XQ14", "gene_name": "PLK4", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XQ14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ14" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { 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= O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XUM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XUM6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XUM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XUM6" } ] } ] }, { "uniprot_ac": "A0A8V0XW11", "gene_name": "RPS6KA2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XW11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XW11" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XW11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XW11" } ] } ] }, { "uniprot_ac": "A0A8V0XW29", "gene_name": "CDKL2", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { 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"https://www.uniprot.org/uniprotkb/A0A8V0YCV8" } ] } ] }, { "uniprot_ac": "A0A8V0YCV9", "gene_name": "SIK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YCV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCV9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YCV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCV9" } ] } ] }, { "uniprot_ac": "A0A8V0YCY4", "gene_name": "AURKB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YCY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCY4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YCY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCY4" } ] } ] }, { "uniprot_ac": "A0A8V0YCY8", "gene_name": "RIOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YCY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCY8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YCY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCY8" } ] } ] }, { "uniprot_ac": "A0A8V0YDH4", "gene_name": "ALPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YDH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDH4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YDH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDH4" } ] } ] }, { "uniprot_ac": "A0A8V0YEV0", "gene_name": "WEE2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YEV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEV0" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0YEV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEV0" } ] } ] }, { "uniprot_ac": "A0A8V0YF83", "gene_name": "WNK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YF83", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF83" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YF83", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF83" } ] } ] }, { "uniprot_ac": "A0A8V0YFH4", "gene_name": "NRK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YFH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFH4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YFH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFH4" } ] } ] }, { "uniprot_ac": "A0A8V0YFL1", "gene_name": "CDK19", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YFL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFL1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0YFL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFL1" } ] } ] }, { "uniprot_ac": "A0A8V0YFP8", "gene_name": "RIPK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YFP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFP8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YFP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFP8" } ] } ] }, { "uniprot_ac": "A0A8V0YFR6", "gene_name": "TNIK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YFR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFR6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YFR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFR6" } ] } ] }, { "uniprot_ac": "A0A8V0YGR1", "gene_name": "RET", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YGR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGR1" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0YGR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGR1" } ] } ] }, { "uniprot_ac": "A0A8V0YGW2", "gene_name": "STK32B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YGW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGW2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YGW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGW2" } ] } ] }, { "uniprot_ac": "A0A8V0YHH2", "gene_name": "STK38L", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YHH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHH2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YHH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHH2" } ] } ] }, { "uniprot_ac": "A0A8V0YHN2", "gene_name": "RPS6KA1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YHN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHN2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YHN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHN2" } ] } ] }, { "uniprot_ac": "A0A8V0YIT6", "gene_name": "ERBB4", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YIT6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIT6" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0YIT6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIT6" } ] } ] }, { "uniprot_ac": "A0A8V0YIV6", "gene_name": "DYRK1A", "activity": [ { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] }, { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] } ] }, { "uniprot_ac": "A0A8V0YJJ1", "gene_name": "ITK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YJJ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJJ1" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0YJJ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJJ1" } ] } ] }, { "uniprot_ac": "A0A8V0YJP9", "gene_name": "RIOK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YJP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJP9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YJP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJP9" } ] } ] }, { "uniprot_ac": "A0A8V0YK18", "gene_name": "CDC42BPB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YK18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK18" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YK18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK18" } ] } ] }, { "uniprot_ac": "A0A8V0YKK3", "gene_name": "MAP4K4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YKK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKK3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YKK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKK3" } ] } ] }, { "uniprot_ac": "A0A8V0YKP8", "gene_name": "VEGFRKDRL", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YKP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKP8" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0YKP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKP8" } ] } ] }, { "uniprot_ac": "A0A8V0YLC3", "gene_name": "PDGFRA", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YLC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLC3" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0YLC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLC3" } ] } ] }, { "uniprot_ac": "A0A8V0YLV1", "gene_name": "MARK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YLV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLV1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YLV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLV1" } ] } ] }, { "uniprot_ac": "A0A8V0YM22", "gene_name": "MYO3AL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YM22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM22" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YM22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM22" } ] } ] }, { "uniprot_ac": "A0A8V0YM96", "gene_name": "STK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YM96", "database": 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} ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YMN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMN5" } ] } ] }, { "uniprot_ac": "A0A8V0YNI5", "gene_name": "NIM1K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YNI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNI5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YNI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNI5" } ] } ] }, { "uniprot_ac": "A0A8V0YNY4", "gene_name": "JAK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YNY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNY4" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0YNY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNY4" } ] } ] }, { "uniprot_ac": "A0A8V0YPR4", "gene_name": "DDR2", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YPR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPR4" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0YPR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPR4" } ] } ] }, { "uniprot_ac": "A0A8V0YRC9", "gene_name": "TNK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YRC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRC9" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", 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"ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YRN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRN4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YRN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRN4" } ] } ] }, { "uniprot_ac": "A0A8V0YSH3", "gene_name": "RPS6KA6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YSH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSH3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YSH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSH3" } ] } ] }, { "uniprot_ac": "A0A8V0YT43", "gene_name": "HCK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YT43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YT43" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0YT43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YT43" } ] } ] }, { "uniprot_ac": "A0A8V0YTI1", "gene_name": "TSSK6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTI1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTI1" } ] } ] }, { "uniprot_ac": "A0A8V0YTL9", "gene_name": "VRK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTL9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTL9" } ] } ] }, { "uniprot_ac": "A0A8V0YTN5", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTN5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTN5" } ] } ] }, { "uniprot_ac": "A0A8V0YTP2", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTP2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTP2" } ] } ] }, { "uniprot_ac": "A0A8V0YUC4", "gene_name": "EPHB3", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YUC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUC4" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0YUC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUC4" } ] } ] }, { "uniprot_ac": "A0A8V0YUJ4", "gene_name": "BTK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YUJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUJ4" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0YUJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUJ4" } ] } ] }, { "uniprot_ac": "A0A8V0YW12", "gene_name": "FRK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YW12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YW12" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0YW12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YW12" } ] } ] }, { "uniprot_ac": "A0A8V0YWW2", "gene_name": "EPHA2", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YWW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YWW2" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0YWW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YWW2" } ] } ] }, { "uniprot_ac": "A0A8V0YXM5", "gene_name": "CSF1R", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YXM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXM5" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0YXM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXM5" } ] } ] }, { "uniprot_ac": "A0A8V0YXZ5", "gene_name": "CDC42BPA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YXZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXZ5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YXZ5", "database": "UniProtKB", "url": 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ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZ74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZ74" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V0YZ74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZ74" } ] } ] }, { "uniprot_ac": "A0A8V0YZE5", "gene_name": "PDGFRB", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZE5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZE5" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0YZE5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZE5" } ] } ] }, { "uniprot_ac": "A0A8V0YZF2", "gene_name": "PAK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", 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"url": "https://www.uniprot.org/uniprotkb/A0A8V0YZM1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0YZM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZM1" } ] }, { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZM1" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0YZM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZM1" } ] } ] }, { "uniprot_ac": "A0A8V0YZP9", "gene_name": "EPHB2", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZP9" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": 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"uniprot_ac": "A0A8V0Z157", "gene_name": "MARK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z157", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z157" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z157", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z157" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A8V0Z157", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z157" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z157", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z157" } ] } ] }, { "uniprot_ac": "A0A8V0Z189", "gene_name": "PKDCCA", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z189", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z189" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0Z189", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z189" } ] } ] }, { "uniprot_ac": "A0A8V0Z1X0", "gene_name": "MAP4K3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z1X0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1X0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z1X0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1X0" } ] } ] }, { "uniprot_ac": "A0A8V0Z283", "gene_name": "MARK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z283", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z283" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z283", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z283" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A8V0Z283", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z283" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z283", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z283" } ] } ] }, { "uniprot_ac": "A0A8V0Z2E3", "gene_name": "PDIK1L", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z2E3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2E3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z2E3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2E3" } ] } ] }, { "uniprot_ac": "A0A8V0Z2Z3", "gene_name": "AAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z2Z3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2Z3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z2Z3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2Z3" } ] } ] }, { "uniprot_ac": "A0A8V0Z3S3", "gene_name": "ALK", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z3S3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3S3" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0Z3S3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3S3" } ] } ] }, { "uniprot_ac": "A0A8V0Z466", "gene_name": "MAP3K19", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z466", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z466" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z466", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z466" } ] } ] }, { "uniprot_ac": "A0A8V0Z4B2", "gene_name": "MERTK", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z4B2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4B2" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0Z4B2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4B2" } ] } ] }, { "uniprot_ac": "A0A8V0Z6K4", "gene_name": "PIK3R4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z6K4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6K4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z6K4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6K4" } ] } ] }, { "uniprot_ac": "A0A8V0Z6T1", "gene_name": "ERN2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z6T1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6T1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z6T1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6T1" } ] } ] }, { 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[ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z8G2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8G2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z8G2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8G2" } ] } ] }, { "uniprot_ac": "A0A8V0Z8T4", "gene_name": "RPS6KC1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z8T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8T4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z8T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8T4" } ] } ] }, { "uniprot_ac": "A0A8V0Z927", "gene_name": "PINK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z927", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z927" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z927", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z927" } ] } ] }, { "uniprot_ac": "A0A8V0Z930", "gene_name": "CAMK2B", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z930", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z930" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V0Z930", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z930" } ] } ] }, { "uniprot_ac": "A0A8V0Z9J0", "gene_name": "CIT", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z9J0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9J0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z9J0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9J0" } ] } ] }, { "uniprot_ac": "A0A8V0ZA06", "gene_name": "CDKL1", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZA06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA06" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0ZA06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA06" } ] } ] }, { "uniprot_ac": "A0A8V0ZA45", "gene_name": "MAP4K5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZA45", "database": "UniProtKB", "url": 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"ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZB38", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB38" } ] } ] }, { "uniprot_ac": "A0A8V0ZBN6", "gene_name": "MAP2K1", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZBN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBN6" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V0ZBN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBN6" } ] } ] }, { "uniprot_ac": "A0A8V0ZBZ2", "gene_name": "MAP3K9", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZBZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBZ2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0ZBZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBZ2" } ] } ] }, { "uniprot_ac": "A0A8V0ZC16", "gene_name": "KALRN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZC16", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC16" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZC16", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC16" } ] } ] }, { "uniprot_ac": "A0A8V0ZC34", "gene_name": "AXL", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZC34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC34" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0ZC34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC34" } ] } ] }, { "uniprot_ac": "A0A8V0ZD40", "gene_name": "CDC2L1", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD40" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD40" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A8V0ZD40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD40" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0ZD40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD40" } ] } ] }, { "uniprot_ac": "A0A8V0ZD48", "gene_name": "PRKCE", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD48" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V0ZD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD48" } ] } ] }, { "uniprot_ac": "A0A8V0ZD60", "gene_name": "STK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD60" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZD60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD60" } ] } ] }, { "uniprot_ac": "A0A8V0ZD70", "gene_name": "DCLK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD70" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZD70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD70" } ] } ] }, { "uniprot_ac": "A0A8V0ZDU6", "gene_name": "SRC", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZDU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDU6" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0ZDU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDU6" } ] } ] }, { "uniprot_ac": "A0A8V0ZDW9", "gene_name": "NEK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZDW9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDW9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZDW9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDW9" } ] } ] }, { "uniprot_ac": "A0A8V0ZE65", "gene_name": "NTRK3", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZE65", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE65" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0ZE65", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE65" } ] } ] }, { "uniprot_ac": "A0A8V0ZER1", "gene_name": "IGF1R", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZER1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZER1" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0ZER1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZER1" } ] } ] }, { "uniprot_ac": "A0A8V0ZFM2", "gene_name": "LMTK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZFM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFM2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZFM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFM2" } ] } ] }, { "uniprot_ac": "A0A8V0ZFP1", "gene_name": "TTBK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZFP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFP1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZFP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFP1" } ] } ] }, { "uniprot_ac": "A0A8V0ZFT3", "gene_name": "LRRK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZFT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFT3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZFT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFT3" } ] } ] }, { "uniprot_ac": "A0A8V0ZGY3", "gene_name": "HIPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZGY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGY3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZGY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGY3" } ] } ] }, { "uniprot_ac": "A0A8V0ZH91", "gene_name": "WNK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZH91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH91" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZH91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH91" } ] } ] }, { "uniprot_ac": "A0A8V0ZI32", "gene_name": "STK16", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZI32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI32" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZI32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI32" } ] } ] }, { "uniprot_ac": "A0A8V0ZK64", "gene_name": "PDPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZK64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK64" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZK64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK64" } ] } ] }, { "uniprot_ac": "A0A8V0ZKA2", "gene_name": "EIF2AK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZKA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKA2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZKA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKA2" } ] } ] }, { "uniprot_ac": "A0A8V0ZKM9", "gene_name": "STK36", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZKM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKM9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZKM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKM9" } ] } ] }, { "uniprot_ac": "A0A8V0ZLU3", "gene_name": "TLK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZLU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLU3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZLU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLU3" } ] } ] }, { "uniprot_ac": "A0A8V0ZMK1", "gene_name": "PIKFYVE", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZMK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMK1" } ] }, { "ec_number": "2.7.1.150", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,5-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZMK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMK1" } ] }, { "ec_number": "2.7.1.150", "activity": "", "evidence": [ { "id": "A0A8V0ZMK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMK1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZMK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMK1" } ] } ] }, { "uniprot_ac": "A0A8V0ZND5", "gene_name": "CSK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZND5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZND5" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0ZND5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZND5" } ] } ] }, { "uniprot_ac": "A0A8V0ZNP7", "gene_name": "SGK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZNP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNP7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZNP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNP7" } ] } ] }, { "uniprot_ac": "A0A8V0ZP30", "gene_name": "LTK", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZP30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP30" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0ZP30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP30" } ] } ] }, { "uniprot_ac": "A0A8V0ZPX2", "gene_name": "ALPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZPX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPX2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZPX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPX2" } ] } ] }, { "uniprot_ac": "A0A8V0ZQJ2", "gene_name": "RPS6KB2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZQJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQJ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZQJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQJ2" } ] } ] }, { "uniprot_ac": "A0A8V0ZQT5", "gene_name": "SLC13A3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZQT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQT5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZQT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQT5" } ] } ] }, { "uniprot_ac": "A0A8V0ZRU7", "gene_name": "EPHB6", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZRU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRU7" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0ZRU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRU7" } ] } ] }, { "uniprot_ac": "A0A8V0ZRX1", "gene_name": "SETD6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZRX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRX1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZRX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRX1" } ] }, { "ec_number": "2.1.1.-", "activity": "", "evidence": [ { "id": "A0A8V0ZRX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRX1" } ] } ] }, { "uniprot_ac": "A0A8V0ZSB4", "gene_name": "SIK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZSB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSB4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZSB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSB4" } ] } ] }, { "uniprot_ac": "A0A8V0ZSN8", "gene_name": "JAK1", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZSN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSN8" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0ZSN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSN8" } ] } ] }, { "uniprot_ac": "A0A8V0ZSP4", "gene_name": "PKN2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZSP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSP4" } ] }, { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZSP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSP4" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V0ZSP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSP4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZSP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSP4" } ] } ] }, { "uniprot_ac": "A0A8V0ZT63", "gene_name": "STK25", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZT63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT63" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZT63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT63" } ] } ] }, { "uniprot_ac": "A0A8V0ZUC6", "gene_name": "PAK6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZUC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUC6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZUC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUC6" } ] } ] }, { "uniprot_ac": "A0A8V0ZUL0", "gene_name": "PASK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZUL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUL0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZUL0", "database": 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} ] }, { "uniprot_ac": "A0A8V0ZWC7", "gene_name": "EIF2AK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZWC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWC7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZWC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWC7" } ] } ] }, { "uniprot_ac": "A0A8V0ZWV8", "gene_name": "TIE1", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZWV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWV8" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0ZWV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWV8" } ] } ] }, { "uniprot_ac": "A0A8V0ZWW1", "gene_name": "MAP3K12", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZWW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWW1" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0ZWW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWW1" } ] } ] }, { "uniprot_ac": "A0A8V0ZXD3", "gene_name": "EPHA4", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZXD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXD3" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0ZXD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXD3" } ] } ] }, { "uniprot_ac": "A0A8V0ZXQ9", "gene_name": "PRKG1", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZXQ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXQ9" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "A0A8V0ZXQ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXQ9" } ] } ] }, { "uniprot_ac": "A0A8V0ZXS7", "gene_name": "ERBB2", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZXS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXS7" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0ZXS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXS7" } ] } ] }, { "uniprot_ac": "A0A8V0ZYU6", "gene_name": "TNNI3K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZYU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZYU6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZYU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZYU6" } ] } ] }, { "uniprot_ac": "A0A8V0ZZE4", "gene_name": "OBSCN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZZE4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZE4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZZE4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZE4" } ] } ] }, { "uniprot_ac": "A0A8V0ZZK5", "gene_name": "STK38", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZZK5", "database": 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"https://www.uniprot.org/uniprotkb/A0A8V1A069" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V1A069", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A069" } ] } ] }, { "uniprot_ac": "A0A8V1A0W4", "gene_name": "ULK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A0W4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0W4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A0W4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0W4" } ] } ] }, { "uniprot_ac": "A0A8V1A0Y8", "gene_name": "MAST2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A0Y8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0Y8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A0Y8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0Y8" } ] } ] }, { "uniprot_ac": "A0A8V1A1P3", "gene_name": "SRPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A1P3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1P3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A1P3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1P3" } ] } ] }, { "uniprot_ac": "A0A8V1A1Y7", "gene_name": "CDK2", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A1Y7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1Y7" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": 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"uniprot_ac": "A0A8V1A4A1", "gene_name": "CAMKK2", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4A1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4A1" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V1A4A1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4A1" } ] } ] }, { "uniprot_ac": "A0A8V1A4J8", "gene_name": "MAPKAPK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4J8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4J8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A4J8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4J8" } ] } ] }, { "uniprot_ac": "A0A8V1A4Q4", "gene_name": "MAPK3", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4Q4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4Q4" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V1A4Q4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4Q4" } ] } ] }, { "uniprot_ac": "A0A8V1A4V7", "gene_name": "HIPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4V7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4V7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A4V7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4V7" } ] } ] }, { "uniprot_ac": "A0A8V1A513", "gene_name": "DAPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A513", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A513" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A513", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A513" } ] } ] }, { "uniprot_ac": "A0A8V1A675", "gene_name": "CSNK1G2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A675", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A675" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A675", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A675" } ] } ] }, { "uniprot_ac": "A0A8V1A7E0", "gene_name": "DYRK3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7E0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E0" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V1A7E0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E0" } ] } ] }, { "uniprot_ac": "A0A8V1A7E9", "gene_name": "SIK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7E9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A7E9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E9" } ] } ] }, { "uniprot_ac": "A0A8V1A7M0", "gene_name": "STK39", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7M0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7M0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A7M0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7M0" } ] } ] }, { "uniprot_ac": "A0A8V1A7N1", "gene_name": "ERBB3", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7N1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7N1" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V1A7N1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7N1" } ] } ] }, { "uniprot_ac": "A0A8V1A7P9", "gene_name": "DCAF1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A7P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P9" } ] } ] }, { "uniprot_ac": "A0A8V1A9R2", "gene_name": "JAK3", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A9R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9R2" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V1A9R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9R2" } ] } ] }, { "uniprot_ac": "A0A8V1A9S5", "gene_name": "NUAK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A9S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9S5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A9S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9S5" } ] } ] }, { "uniprot_ac": "A0A8V1ABF3", "gene_name": "PRKAA2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] } ] }, { "uniprot_ac": "A0A8V1ABP4", "gene_name": "DSTYK", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABP4" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V1ABP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABP4" } ] } ] }, { "uniprot_ac": "A0A8V1ABR8", "gene_name": "CAMK4L", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABR8" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V1ABR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABR8" } ] } ] }, { "uniprot_ac": "A0A8V1AC40", "gene_name": "CDK18", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AC40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC40" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V1AC40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC40" } ] } ] }, { "uniprot_ac": "A0A8V1ACB5", "gene_name": "MAPK13", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACB5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V1ACB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACB5" } ] } ] }, { "uniprot_ac": "A0A8V1ACF6", "gene_name": "PIM1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACF6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ACF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACF6" } ] } ] }, { "uniprot_ac": "A0A8V1ACF7", "gene_name": "ABL1", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACF7" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V1ACF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACF7" } ] } ] }, { "uniprot_ac": "A0A8V1ACK0", "gene_name": "MAPKAPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACK0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ACK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACK0" } ] } ] }, { "uniprot_ac": "A0A8V1ACW2", "gene_name": "WNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACW2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ACW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACW2" } ] } ] }, { "uniprot_ac": "A0A8V1ADF0", "gene_name": "MAP2K2", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ADF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADF0" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V1ADF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADF0" } ] } ] }, { "uniprot_ac": "A0A8V1ADN9", "gene_name": "NLK", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ADN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADN9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V1ADN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADN9" } ] } ] }, { "uniprot_ac": "A0A8V1ADT4", "gene_name": "MKNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ADT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADT4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ADT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADT4" } ] } ] }, { "uniprot_ac": "A0A8V1AE45", "gene_name": "ERN1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AE45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE45" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AE45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE45" } ] } ] }, { "uniprot_ac": "A0A8V1AEH4", "gene_name": "STK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AEH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEH4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AEH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEH4" } ] } ] }, { "uniprot_ac": "A0A8V1AEL3", "gene_name": "ZAP70", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AEL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEL3" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V1AEL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEL3" } ] } ] }, { "uniprot_ac": "A0A8V1AFM7", "gene_name": "INSR", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AFM7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFM7" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V1AFM7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFM7" } ] } ] }, { "uniprot_ac": "A0A8V1AFS4", "gene_name": "STKLD1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AFS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFS4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AFS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFS4" } ] } ] }, { "uniprot_ac": "A0A8V1AG70", "gene_name": "LOC100857512", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AG70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AG70" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AG70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AG70" } ] } ] }, { "uniprot_ac": "A0A8V1AH12", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AH12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH12" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AH12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH12" } ] } ] }, { "uniprot_ac": "A0A8V1AHA8", "gene_name": "NEK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AHA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHA8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AHA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHA8" } ] } ] }, { "uniprot_ac": "A0A8V1AIY7", "gene_name": "AATK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AIY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIY7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AIY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIY7" } ] } ] }, { "uniprot_ac": "A0A8V1AJA4", "gene_name": "RPS6KB1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AJA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJA4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AJA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJA4" } ] } ] }, { "uniprot_ac": "A0A8V1AKW4", "gene_name": "MAP2K4", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AKW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKW4" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V1AKW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKW4" } ] } ] }, { "uniprot_ac": "A0A8V1AM12", "gene_name": "GSG2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AM12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM12" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AM12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM12" } ] } ] }, { "uniprot_ac": "A0A8V1AMK5", "gene_name": "PRKCA", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AMK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMK5" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V1AMK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMK5" } ] } ] }, { "uniprot_ac": "A0A8V1AMK9", "gene_name": "BAZ1B", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AMK9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMK9" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V1AMK9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMK9" } ] } ] }, { "uniprot_ac": "A0A8V1AMQ2", "gene_name": "CAMKK1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AMQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMQ2" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V1AMQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMQ2" } ] } ] }, { "uniprot_ac": "A0A8V1AP60", "gene_name": "KSR1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AP60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP60" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AP60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP60" } ] } ] }, { "uniprot_ac": "E1BQN6", "gene_name": "PRKCZ", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BQN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQN6" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1BQN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQN6" } ] } ] }, { "uniprot_ac": "E1BQV7", "gene_name": "SLK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BQV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQV7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BQV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQV7" } ] } ] }, { "uniprot_ac": "E1BTE1", "gene_name": "WEE2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BTE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BTE1" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "E1BTE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BTE1" } ] } ] }, { "uniprot_ac": "E1BTT3", "gene_name": "BMX", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BTT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BTT3" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "E1BTT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BTT3" } ] } ] }, { "uniprot_ac": "E1BUG0", "gene_name": "CDK12", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] } ] }, { "uniprot_ac": "E1BW33", "gene_name": "SMG1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BW33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BW33" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BW33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BW33" } ] } ] }, { "uniprot_ac": "E1BWA3", "gene_name": "PRKCI", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BWA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWA3" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1BWA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWA3" } ] } ] }, { "uniprot_ac": "E1BWT0", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BWT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWT0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BWT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWT0" } ] } ] }, { "uniprot_ac": "E1BX69", "gene_name": "EIF2AK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BX69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BX69" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BX69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BX69" } ] } ] }, { "uniprot_ac": "E1BY69", "gene_name": "PIM3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BY69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BY69" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BY69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BY69" } ] } ] }, { "uniprot_ac": "E1BYH2", "gene_name": "TAOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BYH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BYH2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BYH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BYH2" } ] } ] }, { "uniprot_ac": "E1C093", "gene_name": "PIK3CG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.154", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.154", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] } ] }, { "uniprot_ac": "E1C2C8", "gene_name": "MATK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C2C8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C2C8" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "E1C2C8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C2C8" } ] } ] }, { "uniprot_ac": "E1C2I2", "gene_name": "MASTL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C2I2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C2I2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C2I2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C2I2" } ] } ] }, { "uniprot_ac": "E1C581", "gene_name": "TBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C581", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C581" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C581", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C581" } ] } ] }, { "uniprot_ac": "E1C6T4", "gene_name": "PRKD3", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C6T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C6T4" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1C6T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C6T4" } ] } ] }, { "uniprot_ac": "E1C764", "gene_name": "BMP2K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C764", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C764" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C764", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C764" } ] } ] }, { "uniprot_ac": "E1C7Z1", "gene_name": "FER", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C7Z1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C7Z1" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "E1C7Z1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C7Z1" } ] } ] }, { "uniprot_ac": "E1C848", "gene_name": "MAP3K8", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C848", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C848" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1C848", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C848" } ] } ] }, { "uniprot_ac": "F1N996", "gene_name": "PTK6", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N996", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N996" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F1N996", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N996" } ] } ] }, { "uniprot_ac": "F1N9Y5", "gene_name": "SYK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N9Y5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N9Y5" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F1N9Y5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N9Y5" } ] } ] }, { "uniprot_ac": "F1NA68", "gene_name": "CDK3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NA68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NA68" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1NA68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NA68" } ] } ] }, { "uniprot_ac": "F1NB57", "gene_name": "PLK2", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NB57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NB57" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "F1NB57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NB57" } ] } ] }, { "uniprot_ac": "F1NBT0", "gene_name": "STK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NBT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NBT0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1NBT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NBT0" } ] } ] }, { "uniprot_ac": "F1NCL8", "gene_name": "FGFR4", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NCL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCL8" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1NCL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCL8" } ] } ] }, { "uniprot_ac": "F1NCX7", "gene_name": "PLK1", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NCX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCX7" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "F1NCX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCX7" } ] } ] }, { "uniprot_ac": "F1NCY7", "gene_name": "MAPKAPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NCY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCY7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1NCY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCY7" } ] } ] }, { "uniprot_ac": "F1NJH1", "gene_name": "PRKCH", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NJH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NJH1" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1NJH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NJH1" } ] } ] }, { "uniprot_ac": "F1NJX6", "gene_name": "EPHA3", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NJX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NJX6" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1NJX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NJX6" } ] } ] }, { "uniprot_ac": "F1NKW3", "gene_name": "MAP3K15", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NKW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NKW3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1NKW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NKW3" } ] } ] }, { "uniprot_ac": "F1NLR7", "gene_name": "CLK3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NLR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NLR7" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "F1NLR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NLR7" } ] } ] }, { "uniprot_ac": "F1NQL9", "gene_name": "ROS1", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NQL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NQL9" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1NQL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NQL9" } ] } ] }, { "uniprot_ac": "F1NUX4", "gene_name": "MTOR", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NUX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NUX4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1NUX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NUX4" } ] } ] }, { "uniprot_ac": "F1NVF2", "gene_name": "MAP2K6", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NVF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NVF2" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "F1NVF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NVF2" } ] } ] }, { "uniprot_ac": "F1NW21", "gene_name": "KDR", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NW21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NW21" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1NW21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NW21" } ] } ] }, { "uniprot_ac": "F1NZY8", "gene_name": "TEC", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NZY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NZY8" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F1NZY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NZY8" } ] } ] }, { "uniprot_ac": "F1P011", "gene_name": "CAMK2A", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1P011", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P011" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "F1P011", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P011" } ] } ] }, { "uniprot_ac": "F1P356", "gene_name": "NUAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1P356", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P356" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1P356", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P356" } ] } ] }, { "uniprot_ac": "F1P4G3", "gene_name": "HIPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1P4G3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P4G3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1P4G3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P4G3" } ] } ] }, { "uniprot_ac": "H9KZZ1", "gene_name": "NTRK1", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "H9KZZ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H9KZZ1" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "H9KZZ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H9KZZ1" } ] } ] }, { "uniprot_ac": "H9KZZ2", "gene_name": "INSRR", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "H9KZZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H9KZZ2" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "H9KZZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H9KZZ2" } ] } ] }, { "uniprot_ac": "O42422", "gene_name": "EPHA7", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "O42422", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O42422" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "O42422", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O42422" } ] } ] }, { "uniprot_ac": "P00523", "gene_name": "SRC", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "P00523", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00523" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "P00523", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00523" } ] } ] }, { "uniprot_ac": "P05625", "gene_name": "RAF1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P05625", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05625" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P05625", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05625" } ] } ] }, { "uniprot_ac": "P08941", "gene_name": "ROS1", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "P08941", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P08941" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "P08941", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P08941" } ] } ] }, { "uniprot_ac": "P09324", "gene_name": "YES1", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "P09324", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P09324" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "P09324", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P09324" } ] } ] }, { "uniprot_ac": "P10741", "gene_name": "MOS", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P10741", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P10741" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P10741", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P10741" } ] } ] }, { "uniprot_ac": "P13387", "gene_name": "EGFR", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "P13387", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13387" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "P13387", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13387" } ] } ] }, { "uniprot_ac": "P13863", "gene_name": "CDK1", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P13863", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13863" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "P13863", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13863" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "P13863", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13863" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "P13863", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13863" } ] } ] }, { "uniprot_ac": "P18460", "gene_name": "FGFR3", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "P18460", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P18460" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "P18460", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P18460" } ] } ] }, { "uniprot_ac": "P18461", "gene_name": "FGFR2", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "P18461", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P18461" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "P18461", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P18461" } ] } ] }, { "uniprot_ac": "P18652", "gene_name": "RPS6KA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P18652", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P18652" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P18652", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P18652" } ] } ] }, { "uniprot_ac": "P21804", "gene_name": "FGFR1", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "P21804", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P21804" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "P21804", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P21804" } ] } ] }, { "uniprot_ac": "P21868", "gene_name": "CSNK2A1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P21868", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P21868" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P21868", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P21868" } ] } ] }, { "uniprot_ac": "P21869", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P21869", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P21869" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P21869", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P21869" } ] } ] }, { "uniprot_ac": "P28693", "gene_name": "EPHB2", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "P28693", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P28693" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "P28693", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P28693" } ] } ] }, { "uniprot_ac": "P29318", "gene_name": "EPHA3", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "P29318", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P29318" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "P29318", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P29318" } ] } ] }, { "uniprot_ac": "P41239", "gene_name": "CSK", "activity": [ { "ec_number": "2.7.10.4", "activity": "ATP + [a protein]-(L-tyrosine) = ADP + [a protein]-(L-tyrosine)-phosphate. The optimal peptide substrate contains the sequence (relative to the phosphorylated tyrosine): Glu-Glu-Asp/Glu-Ile-Tyr-Phe-Phe-Phe-Phe. Physiological substrates are C-terminal tail of Src-family protein kinases.", "evidence": [ { "id": "P41239", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P41239" } ] }, { "ec_number": "2.7.10.4", "activity": "", "evidence": [ { "id": "P41239", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P41239" } ] } ] }, { "uniprot_ac": "P42683", "gene_name": "LCK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "P42683", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P42683" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "P42683", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P42683" } ] } ] }, { "uniprot_ac": "P53666", "gene_name": "LIMK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P53666", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P53666" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P53666", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P53666" } ] } ] }, { "uniprot_ac": "P54755", "gene_name": "EPHA5", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "P54755", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P54755" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "P54755", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P54755" } ] } ] }, { "uniprot_ac": "P67962", "gene_name": "CSNK1A1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P67962", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P67962" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P67962", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P67962" } ] } ] }, { "uniprot_ac": "P79996", "gene_name": "MAPK9", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P79996", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P79996" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "P79996", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P79996" } ] } ] }, { "uniprot_ac": "Q00944", "gene_name": "PTK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q00944", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q00944" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "Q00944", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q00944" } ] } ] }, { "uniprot_ac": "Q02977", "gene_name": "YRK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q02977", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q02977" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "Q02977", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q02977" } ] } ] }, { "uniprot_ac": "Q04982", "gene_name": "BRAF", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q04982", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q04982" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q04982", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q04982" } ] } ] }, { "uniprot_ac": "Q05876", "gene_name": 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O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5ZKI0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKI0" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "Q5ZKI0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKI0" } ] } ] }, { "uniprot_ac": "Q5ZKN1", "gene_name": "CDK9", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5ZKN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKN1" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "Q5ZKN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKN1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q5ZKN1", "database": "UniProtKB", "url": 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The reference sequence was derived from JAENSK010000036.1. 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"MDHTLFGCLRSPHATAQSLHPFSQSSLALHGRSDHMSYPDLSSSSSSCIITGYPNEEGMFASQHHRGHHHHHHHHHHHHQQQQHQALQTNWHIPQMSSPPAAARHSLCLQPDSGGPPELGSSPPVLCSNSSSLGTTTPTGAACAPGDYGRQALSPVETEKRSGKRKSDSSDSQEGNYKSEVNSKPRKERTAFTKEQIRELEAEFAHHNYLTRLRRYEIAVNLDLTERQVKVWFQNRRMKWKRVKGGQQGAAAREKELVNVKKGTLLPSELSGIGAAGLQHTGDSLANDDSHDSDHSSEHAHL", "length": 302, "header": "tr|F1NM26-1|F1NM26_CHICK Isoform 1 of Mesenchyme homeobox 2 OS=Gallus gallus OX=9031 GN=MEOX2 PE=4 SV=1 CANONICAL=F1NM26-1" }, "isoforms": [ { "isoform_ac": "F1NM26-1", "url": "https://www.uniprot.org/uniprotkb/F1NM26/entry#F1NM26-1", "sequence": { "sequence": "MDHTLFGCLRSPHATAQSLHPFSQSSLALHGRSDHMSYPDLSSSSSSCIITGYPNEEGMFASQHHRGHHHHHHHHHHHHQQQQHQALQTNWHIPQMSSPPAAARHSLCLQPDSGGPPELGSSPPVLCSNSSSLGTTTPTGAACAPGDYGRQALSPVETEKRSGKRKSDSSDSQEGNYKSEVNSKPRKERTAFTKEQIRELEAEFAHHNYLTRLRRYEIAVNLDLTERQVKVWFQNRRMKWKRVKGGQQGAAAREKELVNVKKGTLLPSELSGIGAAGLQHTGDSLANDDSHDSDHSSEHAHL", "length": 302, "header": "tr|F1NM26-1|F1NM26_CHICK Isoform 1 of Mesenchyme homeobox 2 OS=Gallus gallus OX=9031 GN=MEOX2 PE=4 SV=1 CANONICAL=F1NM26-1" }, "locus": { "chromosome": "2", "start_pos": 27994897, "end_pos": 27943133, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010009938.1", "url": "https://www.ensembl.org/id/ENSGALT00010009938.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010005821.1", "url": "https://www.ensembl.org/id/ENSGALP00010005821.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A comparative analysis of Meox1 and Meox2 in the developing somites and limbs of the chick embryo.", "journal": "The International journal of developmental biology", "date": "2007", "authors": "Reijntjes Susan, Stricker Sigmar, Mankoo Baljinder S", "evidence": [ { "database": "RefSeq", "id": "NP_001005427", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001005427" } ], "reference": [ { "type": "PubMed", "id": "17939123", "url": 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"id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "F1NM26", "url": "https://www.uniprot.org/uniprotkb/F1NM26" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "F1NM26", "url": "https://www.uniprot.org/uniprotkb/F1NM26" } ], "pmid": "" }, { "name": "DNA-binding transcription activator activity, RNA polymerase II-specific", "id": "GO:0001228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001228", "evidence": [ { "database": "UniProtKB", "id": "F1NM26", "url": "https://www.uniprot.org/uniprotkb/F1NM26" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 129, "end_pos": 131, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1NM26-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 302, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1NM26-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1NM26" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1NM26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NM26" }, { "id": "PRU00108", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00108" } ], "ann_type": "Nucleotide_Binding_Annotation", "uniprotkb_annotation": "Homeobox", "eco_id": "ECO_0000256", "start_pos": 185, "end_pos": 244, "start_aa": "Pro", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 129, "end_pos": 131 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "F1NM51-1", "uniprot_ac": "F1NM51", "uniprot_id": "F1NM51_CHICK", "mass": { "chemical_mass": 171788.0, "monoisotopic_mass": 171788.0 }, "refseq": { "ac": "XP_015151012", "name": "ATP-binding cassette sub-family C member 3 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015151012" }, "gene_names": [ { "name": "ABCC3", "type": "recommended", "evidence": [ { "id": "F1NM51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NM51" } ] }, { "name": "ABCC3", "type": "synonym", "evidence": [ { "id": "XP_015151012", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015151012" } ] } ], "protein_names": [ { "name": "ATP binding cassette subfamily C member 3", "type": "synonym", "evidence": [ { "id": "F1NM51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NM51/entry#names_and_taxonomy" } ] }, { "name": "ATP-binding cassette sub-family C member 3 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015151012", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015151012" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052549.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015151012", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015151012" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NM51", "url": "https://www.uniprot.org/uniprotkb/F1NM51" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ABCC3", "url": "https://www.uniprot.org/uniprotkb/F1NM51", "locus": {} } ], "crossref": [ { "id": "ENSGALG00000007522", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000007522", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd03244", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03244", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd03250", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03250", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd18595", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18595", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd18603", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18603", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "422099", "url": "https://www.ncbi.nlm.nih.gov/gene/422099", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003439", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003439", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003593", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003593", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005292", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005292", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011527", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011527", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017871", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017871", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036640", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036640", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050173", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050173", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056227", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056227", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:422099", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422099", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "KTWIMAF", "url": "https://omabrowser.org/oma/group/KTWIMAF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1NM51", "url": "https://www.orthodb.org/?gene=F1NM51", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24223", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24223", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24223:SF405", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24223:SF405", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00005", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00005", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00664", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00664", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24357", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24357", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-159418", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-159418", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-382556", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-382556", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9749641", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9749641", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9753281", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9753281", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_015151012", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015151012", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "38963", "url": "https://www.rhea-db.org/rhea/38963", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "60128", "url": "https://www.rhea-db.org/rhea/60128", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "F1NM51", "url": "https://www.uniprot.org/uniprotkb/F1NM51", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NM51-1", "url": "https://www.uniprot.org/uniprotkb/F1NM51-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEAFCGSRFWDANLSIHTDSPDLTPCFQNTILAWIPSIYLWTALPFYLLYLKRSKRGYIVLTMLSRFKTLFGVLLWCVSWADLFYSFHELLQSRTPPPVYFVTPLVIGITVLLATLLIQYERLRGVQSSGVLIIFWFLSVLCAVAPFRSKIMTTTAQNHVNERFRSATFYIYFVLLIVELILSCFKEKPPFFSPANTDPNPSPELTSGFLSRLTFWWFTSFAILGYKKPLEEKDLWSLNEDDISKNIVQKLSREWDKEKAECKQKEDVTYRKKSNHALNHVGDGPEEAEVLIRDKRHNRKPSFLKALMRTFGPYFLIGSFFKLIQDLLSFVNPQLLSVLISFVKDKDAPTWWGFLIAALMFACAVLQTLILHQHFQYCFVTGMRLRTGIIGVIYRKSLVITNSAKRSSTVGEIVNLMSVDAQRFMDLVTFLNMLWSAPLQTCLALYFLWQALGPSVLAGVAVMVLLIPFNSAVAIKTRAFQVEQMRYKDSRIKLMNEILGGIKVLKLYAWEPSFSEKVLEMRKNELRVLKKSAYLNSLSNFAWISSPFLVALTTFAVYVLVDEKNTLDAEKAFVSLSLFNILKFPLTMLPQVISNIAQTSVSLKRIQQFLSHDELDPNCVERKVIAPGYAISVKNATFSWGKELKPSLKDINLLVPSGALVAVVGHVGCGKSSLVSALLGEMEKLEGEVAVKGSVAYVPQQAWIQNATLKDNILFGQAPNEQKYQNVLEACALKTDLEVLPGGDHTEIGEKGINLSGGQRQRVSLARAVFSSSDIYLLDDPLSAVDSHVAKHIFDQVIGPDGVLKGKTRILVTHGIGFLPQVDHIVVLADGKISEMGSYQELLKQNKAFAEFLRNYALDENTEEDELTMMEEEEVLLAEDTLSIHTDLADNEPVTNEVRKQFLRQLSVISSEGGECPNKMSTKRRVAEKKPAEPPLPRRNPNEKLIQAETTEVGTVKLTVFWQYMKAVSPVISLIICFLYCCQNAASIGANVWLSDWTNEPVINGTQHNTSMRIGVYAALGLLQGFIVFVSSFTLAMGGINAARKLHTALLENKFHTPQSFYDTTPTGRIINRFSKDIFVIDEVIPPTILMFLGTFFASLSTMIVIVASTPLFAVVVVPLAVLYYFVQRFYVATSRQLKRLESVSRSPIYSHFSETISGTSVIRAYQRERSFIDISDLKVDENQKSYYPGIISNRWLGIRVEFVGNCIVLFAALFAVIGKSSLNAGLVGLSVSYALQVTMALNWMVRTTSDLETNIVAVERIKEYSETETEAPWIIEDKRPPADWPSRGELEFVGYSVRYRKGLDLVLKDLNLRVHGGEKIGIVGRTGAGKSSMTLCLFRILEAAKGEIRIDGVRISEIGLHDLRSRLTIIPQDPVLFSGTLRMNLDPFNKYSDEEVWKALELSHLKRFVSSQPSMLEFECSEGGENLSVGQRQLVCLARALLRKTRVLILDEATAAIDLETDDLIQMTIRTQFEDCTVLTIAHRLNTIMDYTRILVLDNGTIAEFDTPANLIASKGIFYGMAKDAGLV", "length": 1529, "header": "tr|F1NM51-1|F1NM51_CHICK Isoform 1 of ATP binding cassette subfamily C member 3 OS=Gallus gallus OX=9031 GN=ABCC3 PE=1 SV=3 CANONICAL=F1NM51-1" }, "isoforms": [ { "isoform_ac": "F1NM51-1", "url": "https://www.uniprot.org/uniprotkb/F1NM51/entry#F1NM51-1", "sequence": { "sequence": "MEAFCGSRFWDANLSIHTDSPDLTPCFQNTILAWIPSIYLWTALPFYLLYLKRSKRGYIVLTMLSRFKTLFGVLLWCVSWADLFYSFHELLQSRTPPPVYFVTPLVIGITVLLATLLIQYERLRGVQSSGVLIIFWFLSVLCAVAPFRSKIMTTTAQNHVNERFRSATFYIYFVLLIVELILSCFKEKPPFFSPANTDPNPSPELTSGFLSRLTFWWFTSFAILGYKKPLEEKDLWSLNEDDISKNIVQKLSREWDKEKAECKQKEDVTYRKKSNHALNHVGDGPEEAEVLIRDKRHNRKPSFLKALMRTFGPYFLIGSFFKLIQDLLSFVNPQLLSVLISFVKDKDAPTWWGFLIAALMFACAVLQTLILHQHFQYCFVTGMRLRTGIIGVIYRKSLVITNSAKRSSTVGEIVNLMSVDAQRFMDLVTFLNMLWSAPLQTCLALYFLWQALGPSVLAGVAVMVLLIPFNSAVAIKTRAFQVEQMRYKDSRIKLMNEILGGIKVLKLYAWEPSFSEKVLEMRKNELRVLKKSAYLNSLSNFAWISSPFLVALTTFAVYVLVDEKNTLDAEKAFVSLSLFNILKFPLTMLPQVISNIAQTSVSLKRIQQFLSHDELDPNCVERKVIAPGYAISVKNATFSWGKELKPSLKDINLLVPSGALVAVVGHVGCGKSSLVSALLGEMEKLEGEVAVKGSVAYVPQQAWIQNATLKDNILFGQAPNEQKYQNVLEACALKTDLEVLPGGDHTEIGEKGINLSGGQRQRVSLARAVFSSSDIYLLDDPLSAVDSHVAKHIFDQVIGPDGVLKGKTRILVTHGIGFLPQVDHIVVLADGKISEMGSYQELLKQNKAFAEFLRNYALDENTEEDELTMMEEEEVLLAEDTLSIHTDLADNEPVTNEVRKQFLRQLSVISSEGGECPNKMSTKRRVAEKKPAEPPLPRRNPNEKLIQAETTEVGTVKLTVFWQYMKAVSPVISLIICFLYCCQNAASIGANVWLSDWTNEPVINGTQHNTSMRIGVYAALGLLQGFIVFVSSFTLAMGGINAARKLHTALLENKFHTPQSFYDTTPTGRIINRFSKDIFVIDEVIPPTILMFLGTFFASLSTMIVIVASTPLFAVVVVPLAVLYYFVQRFYVATSRQLKRLESVSRSPIYSHFSETISGTSVIRAYQRERSFIDISDLKVDENQKSYYPGIISNRWLGIRVEFVGNCIVLFAALFAVIGKSSLNAGLVGLSVSYALQVTMALNWMVRTTSDLETNIVAVERIKEYSETETEAPWIIEDKRPPADWPSRGELEFVGYSVRYRKGLDLVLKDLNLRVHGGEKIGIVGRTGAGKSSMTLCLFRILEAAKGEIRIDGVRISEIGLHDLRSRLTIIPQDPVLFSGTLRMNLDPFNKYSDEEVWKALELSHLKRFVSSQPSMLEFECSEGGENLSVGQRQLVCLARALLRKTRVLILDEATAAIDLETDDLIQMTIRTQFEDCTVLTIAHRLNTIMDYTRILVLDNGTIAEFDTPANLIASKGIFYGMAKDAGLV", "length": 1529, "header": "tr|F1NM51-1|F1NM51_CHICK Isoform 1 of ATP binding cassette subfamily C member 3 OS=Gallus gallus OX=9031 GN=ABCC3 PE=1 SV=3 CANONICAL=F1NM51-1" }, "locus": { "chromosome": "18", "start_pos": 10816833, "end_pos": 10773614, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070835.1", "url": "https://www.ensembl.org/id/ENSGALT00010070835.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043526.1", "url": "https://www.ensembl.org/id/ENSGALP00010043526.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:422099", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422099", "resource": "KEGG Pathway" }, { "id": "R-GGA-159418", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-159418", "resource": "Reactome", "description": "Recycling of bile acids and salts" }, { "id": "R-GGA-382556", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-382556", "resource": "Reactome", "description": "ABC-family protein mediated transport" }, { "id": "R-GGA-9749641", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9749641", "resource": "Reactome", "description": "Aspirin ADME" }, { "id": "R-GGA-9753281", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9753281", "resource": "Reactome", "description": "Paracetamol ADME" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A9J7GDJ4-1", "protein_name": "Canalicular multispecific organic anion transporter 2", "gene_name": "Abcc3", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MDRLCGSGELGSKFWDSNLSVYTDTPDLTPCFQNSLLAWIPCIYLWAALPCYLFYLRNQQRGYIVLTRLSRLKTALGVLLWCVSWVDLFYAFHRLIYGSAPAPVFFITPLVVGITMLLGTLLIQYERLRGVQSSGVLIIFWLLCVICAIIPFRSKILSATAEGKIADPLRFTTFYIYFALVLCSLILSCFKEKPPLFSPENVDPNPCPEASAGFLSRLSFWWFTKLAILGYRRPLEENDLWTLDEEDCSHKLVQRLLEAWQKQQKRASGPQTAAFEQKTPGEDEVLLRARPKSQKPSFLWALVRTFTSSLLMGVCFKLIQDLLSFINPQLLSILIRFISDPTAPTWWGFLLAGLMFVSSMMQTLILHQYYHCIFVMALRLRTAIIGVIYRKALVITNSVKRESTVGEMVNLMSVDAQRFMDVSPFINLLWSAPLQVILAIYFLWQILGPSVLAGVAVIVLLIPLNGAVSMKMRTYQVQQMKFKDSRIKLMNEILNGIKVLKLYAWEPSFLEQVEGIRLSELQLLRKGAYLQAISTFIWVCTPFLVTLITLGVYVSVDENNVLDAEKAFVSLSLFNILKIPLNMLPQLISGLTQASVSLKRIQDFLNQDELDPQCVERETISPGYAITVHNGTFTWAQDLPPTLHSLNIQIPKGALVAVVGHVGCGKSSLVSALLGEMEKLEGAVCVKGSVAYVPQQAWIQNCTLQENVLFGQPMNPKRYQQALETCALLADLDVLPGGDQTEIGEKGINLSGGQRQRVSLARAVYSDANVFLLDDPLSAVDSHVAKHIFDQVIGPEGVLAGKTRVLVTHGISFLPQTDFIIVLADGQVSEMGHYSALLQHNGSFANFLRNYAPDEDQEGHEVFQDADEEVLLIEDTLSTHTDLTDNEPSMYEVRKQFMRQMSTMSSEGESQNRPVSKRHMNPSEKEMQVTKAKETGALIKDETAETGNVKMSVFWDYAKSVGLYTTLAICLLYAGQSAASIGANVWLSAWANDAVVNGRQNNTSQRLGVYATLGILQGLLVMLSAFTMVVGSVQAARLLHSALLHNKIRSPQSFFDTTPSGRILNRFSKDIYVIDEVLAPTILMLFNSFYTSISTLVVIVASTPLFIVVVLPLAVLYGFVQRFYVATSRQLKRLESISRSPIFSHFSETVTGTSVIRAYGRIEDFKVLSDKKVDNNQKSSYPYIASNRWLGVHVEFVGNCVVLFAALFAVIGRNSLNPGEVGLSVSYALQITLALNWMIRMMSDLESNIIAVERVKEYSKTETEAPWVVEGSRAPEGWPTHGAVEFRNYSVRYRPGLELVLKNLTLRVQGGEKVGIVGRTGAGKSSMTLCLFRILEAAEGEICIDGLNVAHIGLHDLRSQLTIIPQDPILFSGTLRMNLDPFGRYSEEDIWRALELSHLHSFVSSQPAGLDFECSEGGDNLSVGQRQLVCLARALLRKSRVLVLDEATAAIDLETDDLIQGTIRTQFDDCTVLTIAHRLNTIMDYDRVLVLDKGVVAEFDSPTNLIAAGGIFYGMAKDAGLA", "length": 1522 }, "evidence": [ { "id": "F1NM51", "url": "https://omabrowser.org/oma/group/F1NM51/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "B2RX12-1", "protein_name": "ATP-binding cassette sub-family C member 3", "gene_name": "Abcc3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDRLCGSGELGSKFWDSNLSIYTNTPDLTPCFQNSLLAWVPCIYLWAALPCYLFYLRHHQLGYIVLSWLSRLKTALGVLLWCVSWVDLFYSFHGLIHGSSPAPVFFVTPLVVGITMLLATLLIQYERLRGVQSSGVLIIFWLLCVICAIIPFRSKILSALAEGKILDPFRFTTFYIYFALVFCALILSCFKEKPPLFSPENLDTNPCPEASAGFFSRLSFWWFTRLAILGYRRPLEDRDLWSLSEEDCSHKVVQRLLEAWQKQQNQASRSQTATAEPKIPGEDAVLLKPRPKSKQPSFLRALVRTFTSSLLMSACFNLIQNLLGFVNPQLLSILIRFISDPTAPTWWGFLLAGLMFLSSTMQTLILHQYYHCIFVMALRLRTAIIGVIYRKALVITNSVKRESTVGEMVNLMSVDAQRFMDVSPFINLLWSAPLQVILAIYFLWQILGPSALAGVAVIVLLIPLNGAVSMKMKTYQVKQMKFKDSRIKLMSEILNGIKVLKLYAWEPSFLEQVKGIRQSELQLLRKGAYLQAISTFIWICTPFLVTLITLGVYVYVDESNVLDAEKAFVSLSLFNILKIPLNMLPQLISGLTQASVSLKRIQDFLNQNELDPQCVERKTISPGYAITIHNGTFTWAQDLPPTLHSLNIQIPKGALVAVVGPVGCGKSSLVSALLGEMEKLEGVVSVKGSVAYVPQQAWIQNCTLQENVLFGQPMNPKRYQQALETCALLADLDVLPGGDQTEIGEKGINLSGGQRQRVSLARAVYSDANIFLLDDPLSAVDSHVAKHIFDQVIGPEGVLAGKTRVLVTHGISFLPQTDFIIVLAGGQVSEMGHYSALLQHDGSFANFLRNYAPDEDQEDHEAALQNANEEVLLLEDTLSTHTDLTDNEPAIYEVRKQFMREMSSLSSEGEVQNRTMPKKHTNSLEKEALVTKTKETGALIKEEIAETGNVKLSVYWDYAKSMGLCTTLSICLLYGGQSAAAIGANVWLSAWSNDAEEHGQQNKTSVRLGVYAALGILQGLLVMLSAFTMVVGAIQAARLLHEALLHNKIRSPQSFFDTTPSGRILNRFSKDIYVIDEVLAPTILMLLNSFFTSISTIMVIVASTPLFMVVVLPLAVLYGFVQRFYVATSRQLKRLESISRSPIFSHFSETVTGTSVIRAYGRIQDFKVLSDTKVDNNQKSSYPYIASNRWLGVHVEFVGNCVVLFAALFAVIGRNSLNPGLVGLSVSYALQVTMALNWMIRMISDLESNIIAVERVKEYSKTKTEAPWVVESNRAPEGWPTRGMVEFRNYSVRYRPGLELVLKNVTVHVQGGEKVGIVGRTGAGKSSMTLCLFRILEAAEGEIVIDGLNVAHIGLHDLRSQLTIIPQDPILFSGTLRMNLDPFGRYSEEDIWRALELSHLNTFVSSQPAGLDFQCAEGGDNLSVGQRQLVCLARALLRKSRVLVLDEATAAIDLETDDLIQGTIRTQFEDCTVLTIAHRLNTIMDYNRVLVLDKGVVAEFDSPVNLIAAGGIFYGMAKDAGLA", "length": 1523 }, "evidence": [ { "id": "F1NM51", "url": "https://omabrowser.org/oma/group/F1NM51/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F1N3Y6-1", "protein_name": "Multidrug resistance-associated protein 1", "gene_name": "ABCC3", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MDALCGSGELGSKFWDSNLSLHTDNPDLTPCFQNSLLAWLPCIYLWAALPCYLFYLRGHRQGYIVLSHLSRLKTALGVLLWCVSWADLFYSFHGLVHGWPPAPVFFVTPLVVGVTMLLATLLIQYERLQGVRSSGVLIIFWFLCVVCGIIPFRSKILSALTQGKISDPFRFTTFYIYFALVLSALILSCFREKPPFFSPKNMDPNPCPEAGAGFLSRLSFWWFTKLAILGYRRPLEERDLWSLNKEDRSQMVMQRLLEEWKKQQDQAARRQAAEASGKKLSSEGEVLLEGRPRAPEASFLRALMATFSSSFLLSMGFKLIQDLLSFINPQLLSILIRFISNPTAPTWWGFLVAGLMFVCSVMQTLILHQYFHCIFVMGLRFRTGIIGVIYRKALVITNSVKRESTIGEIVNLMSVDAQRFMDVVPFINLLWSAPLQIILAVYFLWQNLGPSVLAGVALMVLLIPLNGAVAVKMRALQVEQMKFKDSRIKLMSEILGGIKVLKLYAWEPSFLKQVEGIRQDELRLMRKVACLHAISTFIWVCTPFLVTLTTLGVYVSVDKNNVLDAEKAFVSVSLFNILKIPLNMLPQLISNLAQTSVSLKRIQHFLSQDELDPQCVERKTITPGYAVIIHNGTFTWAQDLPPALHSLDIQVPKGALVAVVGPVGCGKSSLLSALLGDMEKLEGKVYMKGSVAYVPQQAWIQNCTLQENVLFGQALDPKRYHKALEACALLADLEVLPGGDQTEIGEKGINLSGGQRQRVSVARAVYSDADIFLLDDPLSAVDSHVAKHIFDQVIGPEGVLAGKTRVLVTHGISFLPQTDFVIVLSDGHVSEMGTYSALLQRDGSFANFLRNYAPDEDKEHQEANNRLALEDKEDEEVLMIEDTLSNHTDLTDNEPVTYEVQKQFMRQLSAMSSEGEGQGRSVPRRRLGAAEKVVPATEAKASHVLTQEEKTELGTVKLSVYLDYAKAVGLWTALVICLLYGGQSAAAIGANVWLSAWTDEAAVDSQQNSTSYRLGVYAALGILQGLLVMLSAITMAVGGVQAARLLHQALLHNKMRSPQSFFDTTPSGRILNRFSKDIYVIDELLAPTILMLLNSFYNSISTLVVIVASTPLFAVVILPLAVLYLFVQRFYVATSRQLKRLESVSRSPIYSHFSETVTGSSVIRAYGRSQDFETINDAKVDTNQKSCYPYIASNRWLGIRVEFVGNCVVLFAALFAVTERSSLSPGLVGLSVSYALQVTLALNWMIRTISDLESNIVAVERVKEYSKTEMEAPWVVEGSRPPAGWPLKGEVEFRNYSVRYRPGLELVLKDLSLRVHGGEKVGIVGRTGAGKSSMTLCLFRILEAAEGEIYIDGLNVADIGLHDLRSKLTIIPQDPILFSGTLRMNLDPFGCYSEEDMWQALELSHLHTFVSSQPAGLDFQCSEGGENLSVGQRQLVCLARALLRKSRILVLDEATAAIDLETDDLIQATIRTQFETCTVLTIAHRLNTIMDYTRVLVLDKGTIAEFDSPSNLIAARGIFYGMARDAGLA", "length": 1529 }, "evidence": [ { "id": "F1NM51", "url": "https://omabrowser.org/oma/group/F1NM51/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "O15438-1", "protein_name": "ATP-binding cassette sub-family C member 3", "gene_name": "ABCC3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDALCGSGELGSKFWDSNLSVHTENPDLTPCFQNSLLAWVPCIYLWVALPCYLLYLRHHCRGYIILSHLSKLKMVLGVLLWCVSWADLFYSFHGLVHGRAPAPVFFVTPLVVGVTMLLATLLIQYERLQGVQSSGVLIIFWFLCVVCAIVPFRSKILLAKAEGEISDPFRFTTFYIHFALVLSALILACFREKPPFFSAKNVDPNPYPETSAGFLSRLFFWWFTKMAIYGYRHPLEEKDLWSLKEEDRSQMVVQQLLEAWRKQEKQTARHKASAAPGKNASGEDEVLLGARPRPRKPSFLKALLATFGSSFLISACFKLIQDLLSFINPQLLSILIRFISNPMAPSWWGFLVAGLMFLCSMMQSLILQHYYHYIFVTGVKFRTGIMGVIYRKALVITNSVKRASTVGEIVNLMSVDAQRFMDLAPFLNLLWSAPLQIILAIYFLWQNLGPSVLAGVAFMVLLIPLNGAVAVKMRAFQVKQMKLKDSRIKLMSEILNGIKVLKLYAWEPSFLKQVEGIRQGELQLLRTAAYLHTTTTFTWMCSPFLVTLITLWVYVYVDPNNVLDAEKAFVSVSLFNILRLPLNMLPQLISNLTQASVSLKRIQQFLSQEELDPQSVERKTISPGYAITIHSGTFTWAQDLPPTLHSLDIQVPKGALVAVVGPVGCGKSSLVSALLGEMEKLEGKVHMKGSVAYVPQQAWIQNCTLQENVLFGKALNPKRYQQTLEACALLADLEMLPGGDQTEIGEKGINLSGGQRQRVSLARAVYSDADIFLLDDPLSAVDSHVAKHIFDHVIGPEGVLAGKTRVLVTHGISFLPQTDFIIVLADGQVSEMGPYPALLQRNGSFANFLCNYAPDEDQGHLEDSWTALEGAEDKEALLIEDTLSNHTDLTDNDPVTYVVQKQFMRQLSALSSDGEGQGRPVPRRHLGPSEKVQVTEAKADGALTQEEKAAIGTVELSVFWDYAKAVGLCTTLAICLLYVGQSAAAIGANVWLSAWTNDAMADSRQNNTSLRLGVYAALGILQGFLVMLAAMAMAAGGIQAARVLHQALLHNKIRSPQSFFDTTPSGRILNCFSKDIYVVDEVLAPVILMLLNSFFNAISTLVVIMASTPLFTVVILPLAVLYTLVQRFYAATSRQLKRLESVSRSPIYSHFSETVTGASVIRAYNRSRDFEIISDTKVDANQRSCYPYIISNRWLSIGVEFVGNCVVLFAALFAVIGRSSLNPGLVGLSVSYSLQVTFALNWMIRMMSDLESNIVAVERVKEYSKTETEAPWVVEGSRPPEGWPPRGEVEFRNYSVRYRPGLDLVLRDLSLHVHGGEKVGIVGRTGAGKSSMTLCLFRILEAAKGEIRIDGLNVADIGLHDLRSQLTIIPQDPILFSGTLRMNLDPFGSYSEEDIWWALELSHLHTFVSSQPAGLDFQCSEGGENLSVGQRQLVCLARALLRKSRILVLDEATAAIDLETDNLIQATIRTQFDTCTVLTIAHRLNTIMDYTRVLVLDKGVVAEFDSPANLIAARGIFYGMARDAGLA", "length": 1527 }, "evidence": [ { "id": "F1NM51", "url": "https://omabrowser.org/oma/group/F1NM51/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "O88563-1", "protein_name": "ATP-binding cassette sub-family C member 3", "gene_name": "Abcc3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDRLCGSGELGSKFWDSNLTVYTNTPDLTPCFQNSLLAWVPCIYLWAALPCYLFYLRHHRLGYIVLSCLSRLKTALGVLLWCISWVDLFYSFHGLVHGSSPAPVFFITPLLVGITMLLATLLIQYERLRGVRSSGVLIIFWLLCVICAIIPFRSKILLALAEGKILDPFRFTTFYIYFALVLCAFILSCFQEKPPLFSPENLDTNPCPEASAGFFSRLSFWWFTKLAILGYRRPLEDSDLWSLSEEDCSHKVVQRLLEAWQKQQTQASGPQTAALEPKIAGEDEVLLKARPKTKKPSFLRALVRTFTSSLLMGACFKLIQDLSPSSTHSCSASSSGLFRPHGPYWWGFLLAGLMFVSSTMQTLILHQHYHCIFVMALRIRTAIIGVIYRKALTITNSVKREYTVGEMVNLMSVDAQRFMDVSPFINLLWSAPLQVILAIYFLWQILGPSALAGVAVIVLLIPLNGAVSMKMKTYQVQQMKFKDSRIKLMSEILNGIKVLKLYAWEPTFLEQVEGIRQGELQLLRKGAYLQAISTFIWVCTPFMVTLITLGVYVCVDKNNVLDAEKAFVSLSLFNILKIPLNLLPQLISGMTQTSVSLKRIQDFLNQDELDPQCVERKTISPGRAITIHNGTFSWSKDLPPTLHSINIQIPKGALVAVVGPVGCGKSSLVSALLGEMEKLEGAVSVKGSVAYVPQQAWIQNCTLQENVLFGQPMNPKRYQQALETCALLADLDVLPGGDQTEIGEKGINLSGGQRQRVSLARAVYSDANIFLLDDPLSAVDSHVAKHIFDQVIGPEGVLAGKTRVLVTHGISFLPQTDFIIVLADGQITEMGHYSELLQHDGSFANFLRNYAPDENQEANEGVLQHANEEVLLLEDTLSTHTDLTDTEPAIYEVRKQFMREMSSLSSEGEGQNRPVLKRYTSSLEKEVPATQTKETGALIKEEIAETGNVKLSVYWDYAKSVGLCTTLFICLLYAGQNAVAIGANVWLSAWTNDVEEHGQQNNTSVRLGVYATLGILQGLLVMLSAFTMVVGAIQAARLLHTALLHNQIRAPQSFFDTTPSGRILNRFSKDIYVIHEVLAPTILMLFNSFYTSISTIVVIVASTPLFCVVVLPLAVFYGFVQRFYVATSRQLKRLESVSRSPIFSHFSETVTGTSVIRAYGRVQDFKVLSDAKVDSNQKTTYPYIASNRWLGVHVEFVGNCVVLFSALFAVIGRNSLNPGLVGLSVSYALQVTLSLNWMIRTLSDLESNIIAVERVKEYSKTETEAPWVLESNRAPEGWPRSGVVEFRNYSVRYRPGLELVLKNLTLHVQGGEKVGIVGRTGAGKSSMTLCLFRILEAAEGEIFIDGLNVAHIGLHDLRSQLTIIPQDPILFSGTLRMNLDPFGRYSDEDIWRTLELSHLSAFVSSQPTGLDFQCSEGGDNLSVGQRQLVCLARALLRKSRVLVLDEATAAIDLETDDLIQGTIRTQFEDCTVLTIAHRLNTIMDYNRVLVLDKGVVAEFDSPVNLIAAGGIFYGMAKDAGLA", "length": 1522 }, "evidence": [ { "id": "F1NM51", "url": "https://omabrowser.org/oma/group/F1NM51/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P14772-1", "protein_name": "Bile pigment transporter 1", "gene_name": "BPT1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSSLEVVDGCPYGYRPYPDSGTNALNPCFISVISAWQAVFFLLIGSYQLWKLYKNNKVPPRFKNFPTLPSKINSRHLTHLTNVCFQSTLIICELALVSQSSDRVYPFILKKALYLNLLFNLGISLPTQYLAYFKSTFSMGNQLFYYMFQILLQLFLILQRYYHGSSNERLTVISGQTAMILEVLLLFNSVAIFIYDLCIFEPINELSEYYKKNGWYPPVHVLSYITFIWMNKLIVETYRNKKIKDPNQLPLPPVDLNIKSISKEFKANWELEKWLNRNSLWRAIWKSFGRTISVAMLYETTSDLLSVVQPQFLRIFIDGLNPETSSKYPPLNGVFIALTLFVISVVSVFLTNQFYIGIFEAGLGIRGSLASLVYQKSLRLTLAERNEKSTGDILNLMSVDVLRIQRFFENAQTIIGAPIQIIVVLTSLYWLLGKAVIGGLVTMAIMMPINAFLSRKVKKLSKTQMKYKDMRIKTITELLNAIKSIKLYAWEEPMMARLNHVRNDMELKNFRKIGIVSNLIYFAWNCVPLMVTCSTFGLFSLFSDSPLSPAIVFPSLSLFNILNSAIYSVPSMINTIIETSVSMERLKSFLLSDEIDDSFIERIDPSADERALPAIEMNNITFLWKSKEVLTSSQSGDNLRTDEESIIGSSQIALKNIDHFEAKRGDLVCVVGRVGAGKSTFLKAILGQLPCMSGSRDSIPPKLIIRSSSVAYCSQESWIMNASVRENILFGHKFDQDYYDLTIKACQLLPDLKILPDGDETLVGEKGISLSGGQKARLSLARAVYSRADIYLLDDILSAVDAEVSKNIIEYVLIGKTALLKNKTIILTTNTVSILKHSQMIYALENGEIVEQGNYEDVMNRKNNTSKLKKLLEEFDSPIDNGNESDVQTEHRSESEVDEPLQLKVTESETEDEVVTESELELIKANSRRASLATLRPRPFVGAQLDSVKKTAQKAEKTEVGRVKTKIYLAYIKACGVLGVVLFFLFMILTRVFDLAENFWLKYWSESNEKNGSNERVWMFVGVYSLIGVASAAFNNLRSIMMLLYCSIRGSKKLHESMAKSVIRSPMTFFETTPVGRIINRFSSDMDAVDSNLQYIFSFFFKSILTYLVTVILVGYNMPWFLVFNMFLVVIYIYYQTFYIVLSRELKRLISISYSPIMSLMSESLNGYSIIDAYDHFERFIYLNYEKIQYNVDFVFNFRSTNRWLSVRLQTIGATIVLATAILALATMNTKRQLSSGMVGLLMSYSLEVTGSLTWIVRTTVTIETNIVSVERIVEYCELPPEAQSINPEKRPDENWPSKGGIEFKNYSTKYRENLDPVLNNINVKIEPCEKVGIVGRTGAGKSTLSLALFRILEPTEGKIIIDGIDISDIGLFDLRSHLAIIPQDAQAFEGTVKTNLDPFNRYSEDELKRAVEQAHLKPHLEKMLHSKPRGDDSNEEDGNVNDILDVKINENGSNLSVGQRQLLCLARALLNRSKILVLDEATASVDMETDKIIQDTIRREFKDRTILTIAHRIDTVLDSDKIIVLDQGSVREFDSPSKLLSDKTSIFYSLCEKGGYLK", "length": 1559 }, "evidence": [ { "id": "F1NM51", "url": "https://omabrowser.org/oma/group/F1NM51/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q9LZJ5-1", "protein_name": "ABC transporter C family member 14", "gene_name": "ABCC14", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MRWLSSTWLSDLSCSSSSVIEPSSSLPAPIQWLRFILLSPCPQRLLSSTVDVLFLLILFFFAIQKLCSSSSSRTNGEADITKPLLGRRTRTRTTGLFKTTVVVTIVLSFCSLVLCVSAFFTTRTKLKLVDTLFWLIHAVTNVVIAVLVLHLKRFASPSHPLTLRIYWVFNFVVTTLFTVSGILHLLSDDPAAASLRADDVASFISFPLTAVLLLVSIKGSTGVVVTTSNVTAPAKSNDVVVEKSENVSLYASASFISKTFWLWMNPLLRKGYKSPLNLDQVPTLSPEHRAEKLATLFESKWPKPQENSRNPVRTTLIRCFWKEIAFTAVLAIIRLSVIYVGPVLIQSFVDFTSGKRSSPSQGYYLVLILLIAKFVEVLSTHQFNFNSQKLGMLIRSTLITALYKKGLKLTGSARQNHGVGQIVNYMAVDAQQLSDMMLQLHAIWLMPLQVAAAIVLLYNTLGPSVVTTVIGLTGIFVFILLGTKRNNRYQFSLMMNRDSRMKATNEMLNYMRVIKFQAWEDHFNERILKFREMEFGWLSKFLYSIAGNIIVLWSTPVLISALTFTTAVFLGVKLDAGTVFTTTTIFKILQEPIRTFPQSMISLSQAMISLGRLDAYMMSRELSEETVERSQGCDGNVAVEIKDGSFSWDDEDDEPAIENINFEVKKGELAAIVGTVGSGKSSLLASVLGEMHKLSGKVRVCGTTAYVAQTSWIQNGTVQDNILFGLPMNRSKYNEVLKVCCLEKDMQIMEFGDQTEIGERGINLSGGQKQRIQLARAVYQESDVYLLDDVFSAVDAHTGSDIFKKCVRGALKGKTILLVTHQVDFLHNVDRILVMRDGMIVQSGKYDELVSSGLDFGELVAAHETSMELVEAGSASATAANVPMASPITQRSISIESPRQPKSPKVHRTTSMESPRVLRTTSMESPRLSELNDESIKSFLGSNIPEDGSRLIKEEEREVGQVSFQVYKLYSTEAYGWWGMILVVFFSVAWQASLMASDYWLAYETSAKNEVSFDATVFIRVYVIIAAVSIVLVCLRAFYVTHLGLKTAQIFFKQILNSLVHAPMSFFDTTPSGRILSRASTDQTNVDIFIPFMIGLVATMYTTLLSIFIVTCQYAWPTVFFIIPLGWLNIWYRGYYLASSRELTRLDSITKAPVIHHFSESIAGVMTIRAFKKQPMFRQENVKRVNANLRMDFHNNGSNEWLGFRLELIGSWVLCISALFMVMLPSNIIKPENVGLSLSYGLSLNGVLFWAIYLSCFIENKMVSVERIKQFTDIPAEAKWEIKESRPPPNWPYKGNIRLEDVKVRYRPNTPLVLKGLTIDIKGGEKIGVVGRTGSGKSTLIQVLFRLVEPSGGKIIIDGIDICTLGLHDLRSRFGIIPQEPVLFEGTVRSNIDPTEKYSDEEIWKSLERCQLKDVVASKPEKLDSLVADNGENWSVGQRQLLCLGRVMLKRSRILFLDEATASVDSQTDAMIQKIIREDFSDCTIISIAHRIPTVMDCDRVLVIDAGKAKEYDSPVRLLERQSLFAALVQEYALRSAGI", "length": 1539 }, "evidence": [ { "id": "F1NM51", "url": "https://omabrowser.org/oma/group/F1NM51/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "F1NM51", "url": "https://www.uniprot.org/uniprotkb/F1NM51" } ], "pmid": "" }, { "name": "ABC-type xenobiotic transporter activity", "id": "GO:0008559", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008559", "evidence": [ { "database": "UniProtKB", "id": "F1NM51", "url": "https://www.uniprot.org/uniprotkb/F1NM51" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "F1NM51", "url": "https://www.uniprot.org/uniprotkb/F1NM51" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F1NM51", "url": "https://www.uniprot.org/uniprotkb/F1NM51" } ], "pmid": "" }, { "name": "basolateral plasma membrane", "id": "GO:0016323", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016323", "evidence": [ { "database": "UniProtKB", "id": "F1NM51", "url": "https://www.uniprot.org/uniprotkb/F1NM51" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "lipid transport", "id": "GO:0006869", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006869", "evidence": [ { "database": "UniProtKB", "id": "F1NM51", "url": "https://www.uniprot.org/uniprotkb/F1NM51" } ], "pmid": "" }, { "name": "transmembrane transport", "id": "GO:0055085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055085", "evidence": [ { "database": "UniProtKB", "id": "F1NM51", "url": "https://www.uniprot.org/uniprotkb/F1NM51" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1004, "end_pos": 1006, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1009, "end_pos": 1011, "annotation": "n_glycosylation_sequon" }, { "start_pos": 13, "end_pos": 15, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1427, "end_pos": 1429, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1500, "end_pos": 1502, "annotation": "n_glycosylation_sequon" }, { "start_pos": 635, "end_pos": 637, "annotation": "n_glycosylation_sequon" }, { "start_pos": 706, "end_pos": 708, "annotation": "n_glycosylation_sequon" }, { "start_pos": 754, "end_pos": 756, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "38963", "name": "", "equation": "leukotriene C4(in) + ATP + H2O = leukotriene C4(out) + ADP + phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0ZLX1-1", "A0A8V0ZEP4-1", "A0A8V0ZMB9-1", "Q5F364-1", "A0A8V0XA86-1" ], "evidence": [ { "id": "38963", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/38963" } ] }, { "id": "60128", "name": "", "equation": "17beta-estradiol 17-O-(beta-D-glucuronate)(in) + ATP + H2O = 17beta-estradiol 17-O-(beta-D-glucuronate)(out) + ADP + phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0ZLX1-1", "Q5F364-1", "A0A8V0ZMB9-1" ], "evidence": [ { "id": "60128", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/60128" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A8V0XA86", "gene_name": "RALBP1", "activity": [ { "ec_number": "7.6.2.2", "activity": "daunorubicin(in) + ATP + H2O = daunorubicin(out) + ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XA86", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XA86" } ] }, { "ec_number": "7.6.2.3", "activity": "an S-substituted glutathione(in) + ATP + H2O = an S-substituted glutathione(out) + ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XA86", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XA86" } ] }, { "ec_number": "7.6.2.2", "activity": "", "evidence": [ { "id": "A0A8V0XA86", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XA86" } ] }, { "ec_number": "7.6.2.3", "activity": "", "evidence": [ { "id": "A0A8V0XA86", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XA86" } ] } ] }, { "uniprot_ac": "A0A8V0ZEP4", "gene_name": "ABCC6", "activity": [ { "ec_number": "7.6.2.3", "activity": "an S-substituted glutathione(in) + ATP + H2O = an S-substituted glutathione(out) + ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0ZEP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEP4" } ] }, { 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"secreted frizzled-related protein 5 precursor", "type": "synonym", "evidence": [ { "id": "NP_001305376", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001305376" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: KP729053.1, SRR13267654.34455.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000232.1. On Sep 23, 2021 this sequence version replaced NP_001305376.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001305376", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001305376" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NM64", "url": "https://www.uniprot.org/uniprotkb/F1NM64" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SFRP5", "url": "https://www.uniprot.org/uniprotkb/F1NM64", "locus": { "chromosome": "6", "start_pos": 23087452, "end_pos": 23084497, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010017808", "url": "https://www.ensembl.org/id/ENSGALG00010017808" } ] } } ], "crossref": [ { "id": "F1NM64", "url": "https://alphafold.ebi.ac.uk/entry/F1NM64", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000007515", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000007515", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd03580", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03580", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd07444", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07444", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "423838", "url": "https://www.ncbi.nlm.nih.gov/gene/423838", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001134", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001134", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015526", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015526", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018933", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018933", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020067", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020067", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036790", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036790", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041761", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041761", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:423838", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423838", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "GGQHYDY", "url": "https://omabrowser.org/oma/group/GGQHYDY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1NM64", "url": "https://www.orthodb.org/?gene=F1NM64", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11309", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11309", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11309:SF46", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11309:SF46", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01392", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01392", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01759", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01759", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001305376", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001305376", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1NM64", "url": "https://www.uniprot.org/uniprotkb/F1NM64", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NM64-1", "url": "https://www.uniprot.org/uniprotkb/F1NM64-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPRASGPTGTVTLALLALALAPGEGQHYDYYGWQPESVPRGRFYGREPQCVDIPADMQLCHDVGYKRMRLPNLLEHESMAEAKQQASSWVPLLAKQCHADTQLFLCSLFAPVCLDRPIYPCRSLCEVVRDACAPVMESYGFPWPEMLHCGKFPSDHDLCIAVQFGNNQATPPPVPKICTQCEMEHKADGMMQQMCSSDFVVKMRIKEVIEENGEKRLVAAQKKKVLKLGPLKRKDTKKMVLHMRNTGSCPCPQLANLSGSFLVLGRKVGSRLLLLAIYPWQKHNKEMKFAVKFMFSYPCPLYHPLLYGAGQH", "length": 312, "header": "tr|F1NM64-1|F1NM64_CHICK Isoform 1 of Secreted frizzled-related protein 5 OS=Gallus gallus OX=9031 GN=SFRP5 PE=3 SV=3 CANONICAL=F1NM64-1" }, "isoforms": [ { "isoform_ac": "F1NM64-1", "url": "https://www.uniprot.org/uniprotkb/F1NM64/entry#F1NM64-1", "sequence": { "sequence": "MPRASGPTGTVTLALLALALAPGEGQHYDYYGWQPESVPRGRFYGREPQCVDIPADMQLCHDVGYKRMRLPNLLEHESMAEAKQQASSWVPLLAKQCHADTQLFLCSLFAPVCLDRPIYPCRSLCEVVRDACAPVMESYGFPWPEMLHCGKFPSDHDLCIAVQFGNNQATPPPVPKICTQCEMEHKADGMMQQMCSSDFVVKMRIKEVIEENGEKRLVAAQKKKVLKLGPLKRKDTKKMVLHMRNTGSCPCPQLANLSGSFLVLGRKVGSRLLLLAIYPWQKHNKEMKFAVKFMFSYPCPLYHPLLYGAGQH", "length": 312, "header": "tr|F1NM64-1|F1NM64_CHICK Isoform 1 of Secreted frizzled-related protein 5 OS=Gallus gallus OX=9031 GN=SFRP5 PE=3 SV=3 CANONICAL=F1NM64-1" }, "locus": { "chromosome": "6", "start_pos": 23086274, "end_pos": 23084537, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043029.1", "url": "https://www.ensembl.org/id/ENSGALT00010043029.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025519.1", "url": "https://www.ensembl.org/id/ENSGALP00010025519.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 8, "start_aa": "Thr", "end_pos": 8, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr8", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:423838", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423838", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZTV6-1", "protein_name": "Secreted frizzled-related protein 5", "gene_name": "Sfrp5", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRVAGGARTAALALLLGALHGAPARGQEYDYYGWQTEPLHGRSYSKPPQCLDIPADLPLCHTVGYKRMRLPNLLEHESLAEVKQQASSWLPLLAKRCHSDTQVFLCSLFAPVCLDRPIYPCRSLCEAVRAGCAPLMEAYGFPWPEMLHCHKFPLDNDLCIAVQFGHLPATAPPVTKICAQCEIEHSADGLMEQMCSSDFVVKMRIKEIKIDNGDRKLIGAQKKKKLLKAGPLKRKDTKKLVLHMKNGASCPCPQLDNLTGSFLVMGRKVEGQLLLTAVYRWDKKNKEMKFAVKFMFSYPCSLYYPFFYGAAEPH", "length": 314 }, "evidence": [ { "id": "F1NM64", "url": "https://omabrowser.org/oma/group/F1NM64/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1S8X3-1", "protein_name": "Secreted frizzled-related protein 5", "gene_name": "SFRP5", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRAAARGARAAALALLLGALHGAPAHGEEYDYYGWQTEPLHGRSYSKPPQCLDIPADLPLCHTVGYKRMRLPNLLEHESLAEVKQQASSWLPLLAKRCHSDTQVFLCSLFAPVCLDRPIYPCRSLCEAVRAGCAPLMEAYGFPWPEMLHCHKFPLDNDLCIAVQFGHLPATAPPVTKICAQCEMEHSADGLMEQMCSSDFVVKMRLKEIKIENGDRKLIGAQKKKKLLKPGPLKRKDTKRLVLHMKNGAGCPCPQLDSLAGSFLVMGRKVDGQLLLMAVYRWDKKNKEMKFAVKFMFSYPCSLYYPFFYGAAEPH", "length": 315 }, "evidence": [ { "id": "F1NM64", "url": "https://omabrowser.org/oma/group/F1NM64/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q5T4F7-1", "protein_name": "Secreted frizzled-related protein 5", "gene_name": "SFRP5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRAAAAGGGVRTAALALLLGALHWAPARCEEYDYYGWQAEPLHGRSYSKPPQCLDIPADLPLCHTVGYKRMRLPNLLEHESLAEVKQQASSWLPLLAKRCHSDTQVFLCSLFAPVCLDRPIYPCRSLCEAVRAGCAPLMEAYGFPWPEMLHCHKFPLDNDLCIAVQFGHLPATAPPVTKICAQCEMEHSADGLMEQMCSSDFVVKMRIKEIKIENGDRKLIGAQKKKKLLKPGPLKRKDTKRLVLHMKNGAGCPCPQLDSLAGSFLVMGRKVDGQLLLMAVYRWDKKNKEMKFAVKFMFSYPCSLYYPFFYGAAEPH", "length": 317 }, "evidence": [ { "id": "F1NM64", "url": "https://omabrowser.org/oma/group/F1NM64/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9WU66-1", "protein_name": "Secreted frizzled-related protein 5", "gene_name": "Sfrp5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWVAWSARTAALALLLGALHGAPTRGQEYDYYGWQAEPLHGRSYSKPPQCLDIPADLPLCHTVGYKRMRLPNLLEHESLAEVKQQASSWLPLLAKRCHSDTQVFLCSLFAPVCLDRPIYPCRSLCEAARAGCAPLMEAYGFPWPEMLHCHKFPLDNDLCIAVQFGHLPATAPPVTKICAQCEMEHSADGLMEQMCSSDFVVKMRIKEIKIDNGDRKLIGAQKKKKLLKAGPLKRKDTKKLVLHMKNGASCPCPQLDNLTGSFLVMGRKVEGQLLLTAVYRWDKKNKEMKFAVKFMFSYPCSLYYPFFYGAAEPH", "length": 314 }, "evidence": [ { "id": "F1NM64", "url": "https://omabrowser.org/oma/group/F1NM64/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9XSC1-1", "protein_name": "Secreted frizzled-related protein 5", "gene_name": "SFRP5", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MRAAAGGARAAVLALLLGALHGAPARGEEYDYYGWQTEPLHGRSYSKPPQCLDIPADLPLCHTVGYKRMRLPNLLEHESLAEVKQQASSWLPLLAKRCHSDTQVFLCSLFAPVCLDRPIYPCRSLCEAVRAGCAPLMEAYGFPWPEMLHCHKFPLDNDLCIAVQFGHLPATAPPVTKICAQCEMEHSADGLMEQMCSSDFVVKMRIKEIKIENGDRKLIGAQKKKKLLKSGPLKRKDTKRLVLHMKNSAGCPCPQLDSLAGSFLVMGRKVDGQLLLMAVYRWDKKNKEMKFAVKFMFSYPCSLYYPFFYGAAEPH", "length": 315 }, "evidence": [ { "id": "F1NM64", "url": "https://omabrowser.org/oma/group/F1NM64/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "F1NM64", "url": "https://www.uniprot.org/uniprotkb/F1NM64" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 9, "go_terms": [ { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "F1NM64", "url": "https://www.uniprot.org/uniprotkb/F1NM64" } ], "pmid": "" }, { "name": "negative regulation of cell population proliferation", "id": "GO:0008285", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008285", "evidence": [ { "database": "UniProtKB", "id": "F1NM64", "url": "https://www.uniprot.org/uniprotkb/F1NM64" } ], "pmid": "" }, { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "F1NM64", "url": "https://www.uniprot.org/uniprotkb/F1NM64" } ], "pmid": "" }, { "name": "negative regulation of canonical Wnt signaling pathway", "id": "GO:0090090", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090090", "evidence": [ { "database": "UniProtKB", "id": "F1NM64", "url": "https://www.uniprot.org/uniprotkb/F1NM64" } ], "pmid": "" }, { "name": "digestive tract morphogenesis", "id": "GO:0048546", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048546", "evidence": [ { "database": "UniProtKB", "id": "F1NM64", "url": "https://www.uniprot.org/uniprotkb/F1NM64" } ], "pmid": "" }, { "name": "canonical Wnt signaling pathway", "id": "GO:0060070", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060070", "evidence": [ { "database": "UniProtKB", "id": "F1NM64", "url": "https://www.uniprot.org/uniprotkb/F1NM64" } ], "pmid": "" }, { "name": "negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction", "id": "GO:0051898", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051898", "evidence": [ { "database": "UniProtKB", "id": "F1NM64", "url": "https://www.uniprot.org/uniprotkb/F1NM64" } ], "pmid": "" }, { "name": "negative regulation of non-canonical Wnt signaling pathway", "id": "GO:2000051", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000051", "evidence": [ { "database": "UniProtKB", "id": "F1NM64", "url": "https://www.uniprot.org/uniprotkb/F1NM64" } ], "pmid": "" }, { "name": "non-canonical Wnt signaling pathway", "id": "GO:0035567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035567", "evidence": [ { "database": "UniProtKB", "id": "F1NM64", "url": "https://www.uniprot.org/uniprotkb/F1NM64" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "Wnt-protein binding", "id": "GO:0017147", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017147", "evidence": [ { "database": "UniProtKB", "id": "F1NM64", "url": "https://www.uniprot.org/uniprotkb/F1NM64" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 256, "end_pos": 258, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1NM64-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 312, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1NM64-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1NM64" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 8 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 256, "end_pos": 258 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1NM71-1", "uniprot_ac": "F1NM71", "uniprot_id": "F1NM71_CHICK", "mass": { "chemical_mass": 19610.0, "monoisotopic_mass": 19610.0 }, "refseq": { "ac": "NP_001264569", "name": "centrin-2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264569" }, "gene_names": [ { "name": "CETN2", "type": "recommended", "evidence": [ { "id": "F1NM71", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NM71" } ] }, { "name": "CETN1", "type": "synonym", "evidence": [ { "id": "NP_001264569", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264569" } ] }, { "name": "CETN2", "type": "synonym", "evidence": [ { "id": "NP_001264569", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264569" } ] } ], "protein_names": [ { "name": "Centrin 2", "type": "synonym", "evidence": [ { "id": "F1NM71", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NM71/entry#names_and_taxonomy" } ] }, { "name": "centrin 1", "type": "synonym", "evidence": [ { "id": "NP_001264569", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264569" } ] }, { "name": "centrin, EF-hand protein, 2", "type": "synonym", "evidence": [ { "id": "NP_001264569", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264569" } ] }, { "name": "centrin-2", "type": "synonym", "evidence": [ { "id": "NP_001264569", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264569" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: HAEK01038359.1, HAEK01196108.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000071.1. On Apr 13, 2013 this sequence version replaced XP_420280.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001264569", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264569" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NM71", "url": "https://www.uniprot.org/uniprotkb/F1NM71" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CETN2", "url": "https://www.uniprot.org/uniprotkb/F1NM71", "locus": { "chromosome": "4", "start_pos": 11246805, "end_pos": 11242304, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012469", "url": "https://www.ensembl.org/id/ENSGALG00010012469" } ] } } ], "crossref": [ { "id": "F1NM71", "url": "https://alphafold.ebi.ac.uk/entry/F1NM71", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000007510", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000007510", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00051", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00051", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "422303", "url": "https://www.ncbi.nlm.nih.gov/gene/422303", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000629", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000629", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002048", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002048", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011992", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011992", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018247", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018247", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050230", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050230", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:422303", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422303", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HPGLTQQ", "url": "https://omabrowser.org/oma/group/HPGLTQQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1NM71", "url": "https://www.orthodb.org/?gene=F1NM71", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23048", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23048", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23048:SF59", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23048:SF59", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13499", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13499", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-2565942", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2565942", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-3108214", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3108214", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-380259", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-380259", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-380270", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-380270", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-380284", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-380284", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-380320", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-380320", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-5620912", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5620912", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-5696394", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5696394", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-5696395", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5696395", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-8854518", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8854518", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9646399", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9646399", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001264569", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264569", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1NM71", "url": "https://www.uniprot.org/uniprotkb/F1NM71", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NM71-1", "url": "https://www.uniprot.org/uniprotkb/F1NM71-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASSFKKPSLGAASQRKKSSPKPELTEEQKQEIREAFDLFDTDGTGNIDVKELKVAMRALGFEPKKEEIKKMISDIDKEGTGKISFNDFLVVMTQKMAEKDSKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDGDGEVNEQEFLRIMKKTSLY", "length": 172, "header": "tr|F1NM71-1|F1NM71_CHICK Isoform 1 of Centrin 2 OS=Gallus gallus OX=9031 GN=CETN2 PE=1 SV=2 CANONICAL=F1NM71-1" }, "isoforms": [ { "isoform_ac": "F1NM71-1", "url": "https://www.uniprot.org/uniprotkb/F1NM71/entry#F1NM71-1", "sequence": { "sequence": "MASSFKKPSLGAASQRKKSSPKPELTEEQKQEIREAFDLFDTDGTGNIDVKELKVAMRALGFEPKKEEIKKMISDIDKEGTGKISFNDFLVVMTQKMAEKDSKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDGDGEVNEQEFLRIMKKTSLY", "length": 172, "header": "tr|F1NM71-1|F1NM71_CHICK Isoform 1 of Centrin 2 OS=Gallus gallus OX=9031 GN=CETN2 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"annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052576.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 1, 2022 this sequence version replaced XP_040526865.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040526865", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040526865" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NMA2", "url": "https://www.uniprot.org/uniprotkb/F1NMA2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SULT1E1", "url": "https://www.uniprot.org/uniprotkb/F1NMA2", "locus": {} } ], "crossref": [ { "id": "F1NMA2", "url": "https://alphafold.ebi.ac.uk/entry/F1NMA2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000011812", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000011812", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "422662", "url": "https://www.ncbi.nlm.nih.gov/gene/422662", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000863", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000863", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:422662", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422662", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "IAEEWSQ", "url": "https://omabrowser.org/oma/group/IAEEWSQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1NMA2", "url": "https://www.orthodb.org/?gene=F1NMA2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11783", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11783", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00685", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00685", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-156584", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-156584", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9753281", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9753281", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_040526865", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040526865", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1NMA2", "url": "https://www.uniprot.org/uniprotkb/F1NMA2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NMA2-1", "url": "https://www.uniprot.org/uniprotkb/F1NMA2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGNDEVIRQDLGCLYDIPLYKCFVAGWPQVEAFQARPDDLLIATYPKSGTTWLSEILDAIYHDGDLEKCRRDAIYNRVPFLEMKAPGILSGVEQLEKIPSPRLVKTHLPVHLLPASFQEKDCKVIYMARNAKDVVISYYYFYQMAKIHPDPGTLSEFLQAFMDGKVAYGSWYKHVKGWWEKRHEKRLLYLFYEDMKKDPRREIQKILQFLGKEVAEETVARILHHTSFQEMKKNPATNYETMPTELMDHSLSPFMRKGISGDWANHFTVAQNERFDQHYQQQMAGSDLCFQMEA", "length": 294, "header": "tr|F1NMA2-1|F1NMA2_CHICK Isoform 1 of Sulfotransferase OS=Gallus gallus OX=9031 GN=SULT1E1 PE=1 SV=3 CANONICAL=F1NMA2-1" }, "isoforms": [ { "isoform_ac": "F1NMA2-1", "url": "https://www.uniprot.org/uniprotkb/F1NMA2/entry#F1NMA2-1", "sequence": { "sequence": "MGNDEVIRQDLGCLYDIPLYKCFVAGWPQVEAFQARPDDLLIATYPKSGTTWLSEILDAIYHDGDLEKCRRDAIYNRVPFLEMKAPGILSGVEQLEKIPSPRLVKTHLPVHLLPASFQEKDCKVIYMARNAKDVVISYYYFYQMAKIHPDPGTLSEFLQAFMDGKVAYGSWYKHVKGWWEKRHEKRLLYLFYEDMKKDPRREIQKILQFLGKEVAEETVARILHHTSFQEMKKNPATNYETMPTELMDHSLSPFMRKGISGDWANHFTVAQNERFDQHYQQQMAGSDLCFQMEA", "length": 294, "header": "tr|F1NMA2-1|F1NMA2_CHICK Isoform 1 of Sulfotransferase OS=Gallus gallus OX=9031 GN=SULT1E1 PE=1 SV=3 CANONICAL=F1NMA2-1" }, "locus": { "chromosome": "4", "start_pos": 51310534, "end_pos": 51309080, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010011814.1", "url": "https://www.ensembl.org/id/ENSGALT00010011814.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010006624.1", "url": "https://www.ensembl.org/id/ENSGALP00010006624.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "gga:422662", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422662", "resource": "KEGG Pathway" }, { "id": "R-GGA-156584", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-156584", "resource": "Reactome", "description": "Cytosolic sulfonation of small molecules" }, { "id": "R-GGA-9753281", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9753281", "resource": "Reactome", "description": "Paracetamol ADME" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287BPX1-1", "protein_name": "Sulfotransferase", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDNKQDIFRRDLVDFQGVPLFWSITEEWSQVESFESRPDDLLISTYPKSGTTWTSEILDLIYNNGDVEKCKRDAIYKRVPFMELIVPGLSNGVKELNDMQSPRLVKTHLPVQLLPSSFWKNNCKIVYVARNAKDVAVSYYYFYQMAKIHPEPGTWEEFLDKFIAGKVAFGSWYDHVKGWWEKRKDHRILYLFFEDMKKDPKCEIQKLLKFLDKDLPEETVDKILYHSSFDMMKQNPSANYTTLPKFSMDHSLSPFMRKGISGDWKNQFTVAQYERFEEDYKKKMKGSTLQFCSEI", "length": 295 }, "evidence": [ { "id": "F1NMA2", "url": "https://omabrowser.org/oma/group/F1NMA2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A9J7F197-1", "protein_name": "Sulfotransferase", "gene_name": "LOC100763252", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MDKKLDIFRRELVDVHGIPLFWSIAEQWSQVESFEARPDDLLISTYPKSGTTWISEILDLIYNNGDAEKCKRDAIYKRVPFMELIIPGLSNGVELLKNMHSPRLVKTHLPVQLLPSSFWKNDCKMVYVARNAKDVAVSYYYFYQMAKIHPEPGTWEEFLDKFMAGQVGFGSWYDHVKGWWEKRNDYRILYLFYEDMKEDPKYEIQKLLKFLEKDMPEEIVNKILYHSSFNVMKENPNANYTTMKKEEMDHAVSPFMRKGISGDWKNQFTVAQYEKFEDDYVKKMKESTLKFRSEI", "length": 295 }, "evidence": [ { "id": "F1NMA2", "url": "https://omabrowser.org/oma/group/F1NMA2/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "E1BAC7-1", "protein_name": "Sulfotransferase", "gene_name": "SULT1D1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MDSKLDIFRRELVDVQGIPLFWSIVEEWSQVESFENRPDDLLIATYPKSGTTWISEILDLIYNHGDVEKCKRDAIYKRVPFMELIIPRLTNGVEDLNDMQSPRLVKKHLPVQLLPSSFWKNNCKMVYVARNANDVAVSYYYFYQMAKMHPDPGTWEEFLDKFMTGKVAFGSWYDHVKGWWEKKKDYCKLYLFYEDMKQDPKCEIQKLLKFLDKDLPEETVDKILYHSSFDMMKQNPSANYTTMPKFCMDHSVSPFMRKGVSGDWKNQFTVVQYERFEEDYEKKMKGSTLQFHSEI", "length": 295 }, "evidence": [ { "id": "F1NMA2", "url": "https://omabrowser.org/oma/group/F1NMA2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "G3V9R3-1", "protein_name": "Sulfotransferase 1 family member D1", "gene_name": "Sult1d1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDNKLDVFRRELVDVQGIPLFWSIAEQWSQVESFEARPDDILISTYPKSGTTWISEILDLIYNNGDAEKCKRDAIYRRVPFMELIIPGITNGVEMLNNMQSPRLVKTHLPVQLLPSSFWKNDCKMIYVARNAKDVAVSYYYFHQMAKMHPEPGTWEEFLEKFMAGQVSFGPWYDHVKGWWEKRKEYRILYLFYEDMKEDPKCEIQKVLKFLEKDIPEEVVNKILYHSSFSVMKANPSANYTTMMKEEMDQSVSPFMRKGISGDWKNQFTVAQYEKFEEDYVKKMEESTLKFRSEI", "length": 295 }, "evidence": [ { "id": "F1NMA2", "url": "https://omabrowser.org/oma/group/F1NMA2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q3UZZ6-1", "protein_name": "Sulfotransferase 1 family member D1", "gene_name": "Sult1d1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDNKLDVFRRELVDVEGIPLFWSIAEHWSQVESFEARPDDILISTYPKSGTTWVSEILDLIYNNGDAEKCKRDAIYKRVPFMELIIPGITNGVEMLNNMPSPRIVKTHLPVQLLPSSFWKNDCKIIYVARNAKDVVVSYYYFYQMAKIHPEPGTWEEFLEKFMAGQVSFGPWYDHVKSWWEKRKEYRILYLFYEDMKENPKCEIQKILKFLEKDIPEEILNKILYHSSFSVMKENPSANYTTMMKEEMDHSVSPFMRKGISGDWKNQFTVAQYEKFEEDYVKKMEDSTLKFRSEI", "length": 295 }, "evidence": [ { "id": "F1NMA2", "url": "https://omabrowser.org/oma/group/F1NMA2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "sulfation", "id": "GO:0051923", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051923", "evidence": [ { "database": "UniProtKB", "id": "F1NMA2", "url": "https://www.uniprot.org/uniprotkb/F1NMA2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "aryl sulfotransferase activity", "id": "GO:0004062", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004062", "evidence": [ { "database": "UniProtKB", "id": "F1NMA2", "url": "https://www.uniprot.org/uniprotkb/F1NMA2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1NMA2", "url": "https://www.uniprot.org/uniprotkb/F1NMA2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-GGA-158468", "name": "SULT1A1 dimer sulfonates PARA to PARA-SO4", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [ "R-ALL-158471" ], "output_participant_list": [ "R-ALL-158472" ], "enzyme_list": [ "F1NMA2-1" ], "evidence": [ { "id": "R-GGA-158468", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-158468" } ] }, { "id": "R-GGA-158849", "name": "Phenol can form a sulfate conjugate", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [ "R-ALL-158858" ], "output_participant_list": [ "R-ALL-158850" ], "enzyme_list": [ "F1NMA2-1" ], "evidence": [ { "id": "R-GGA-158849", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-158849" } ] }, { "id": "R-GGA-158860", "name": "SULT1A1 dimer sulfonates NHABP", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [ "R-ALL-158847" ], "output_participant_list": [ "R-ALL-158859" ], "enzyme_list": [ "F1NMA2-1" ], "evidence": [ { "id": "R-GGA-158860", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-158860" } ] }, { "id": "R-GGA-159358", "name": "SULT1A3,4 dimers sulfate DA to DAOS", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [ "R-ALL-159362" ], "output_participant_list": [ "R-ALL-159352" ], "enzyme_list": [ "F1NMA2-1" ], "evidence": [ { "id": "R-GGA-159358", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-159358" } ] }, { "id": "R-GGA-176474", "name": "3,3'-diiodothyronine + PAPS => 3,3'-diiodothyronine 4-sulfate + PAP", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [ "R-ALL-176486" ], "output_participant_list": [ "R-ALL-176519" ], "enzyme_list": [ "A0A8V0XP18-1", "A0A8V0XR93-1", "F1NMA2-1", "A0A8V0XZJ5-1", "A0A8V0XEJ6-1", "A0A8V0XLB2-1" ], "evidence": [ { "id": "R-GGA-176474", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-176474" } ] }, { "id": "R-GGA-176517", "name": "SULTs transfer (SO4)2- group to PREG", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [ "R-ALL-176665" ], "enzyme_list": [ "F1NMA2-1", "A0A8V0XEJ6-1", "A0A8V0XLB2-1" ], "evidence": [ { "id": "R-GGA-176517", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-176517" } ] }, { "id": "R-GGA-176521", "name": "beta-estradiol + PAPS => beta-estradiol 3-sulfate + PAP", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [ "R-ALL-176492" ], "enzyme_list": [ "F1NMA2-1" ], "evidence": [ { "id": "R-GGA-176521", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-176521" } ] }, { "id": "R-GGA-176585", "name": "3,5,3'-triiodothyronine + PAPS => 3,5,3'-triiodothyronine 4-sulfate + PAP", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [ "R-ALL-176667" ], "output_participant_list": [ "R-ALL-176564" ], "enzyme_list": [ "A0A8V0XP18-1", "A0A8V0XR93-1", "F1NMA2-1", "E1C8B2-1", "A0A8V0XZJ5-1", "A0A8V0XEJ6-1", "A0A8V0XLB2-1" ], "evidence": [ { "id": "R-GGA-176585", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-176585" } ] }, { "id": "R-GGA-176631", "name": "dehydroepiandrosterone (DHEA) + PAPS => DHEA sulfate + PAP", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [ "R-ALL-176626" ], "output_participant_list": [ "R-ALL-176496" ], "enzyme_list": [ "F1NMA2-1", "A0A8V0XEJ6-1", "A0A8V0XLB2-1" ], "evidence": [ { "id": "R-GGA-176631", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-176631" } ] }, { "id": "R-GGA-176646", "name": "p-nitrophenol + PAPS => p-nitrophenol sulfate + PAP", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [ "R-ALL-5695950" ], "output_participant_list": [ "R-ALL-176600" ], "enzyme_list": [ "F1NMA2-1", "E1C8B2-1" ], "evidence": [ { "id": "R-GGA-176646", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-176646" } ] }, { "id": "R-GGA-176664", "name": "estrone + PAPS => estrone 3-sulfate + PAP", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [ "R-ALL-176575" ], "output_participant_list": [ "R-ALL-176501" ], "enzyme_list": [ "F1NMA2-1", "A0A8V0XEJ6-1", "A0A8V0XLB2-1" ], "evidence": [ { "id": "R-GGA-176664", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-176664" } ] }, { "id": "R-GGA-176669", "name": "N-hydroxy-2-acetylaminofluorene + PAPS => 2-acetylaminofluorene-N-sulfate + PAP", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [ "R-ALL-176566" ], "output_participant_list": [ "R-ALL-176500" ], "enzyme_list": [ "F1NMA2-1" ], "evidence": [ { "id": "R-GGA-176669", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-176669" } ] }, { "id": "R-GGA-9753277", "name": "SULT dimers sulfate APAP to APAP-SO3", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. 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"PTHR22603", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22603", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22603:SF91", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22603:SF91", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01633", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01633", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-1483213", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1483213", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_416426", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_416426", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1NMC4", "url": "https://www.uniprot.org/uniprotkb/F1NMC4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NMC4-1", "url": "https://www.uniprot.org/uniprotkb/F1NMC4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSNYIHVPPGSPEVPKLDITVSEREGPGCRQGALQLLRRLRPHWRPEEVTLQLFTDGITNKLIGCYVGDTTDDVVLVRIYGNKTELLVDRDEEVKSFRVLQAHGCAPQLYCTFNNGLCYEFMQGEALDPEHVCNPDIFRLIARQLAKIHTIHAHNGWIPKSNLWLKMGKYFSLIPTEFADEEVNKRFLSEIPSPQVLQEEMAWMKERLSNLGSPVVLCHNDLLCKNIIYNKKRGDVQFIDYEYSGYNYLAYDIGNHFNEFAGVNEVDYSLYPNRKLQEQWLRSYLEAYKEYKGFGTEVSEKEVEVLYVQVNQFALASHFFWGLWALIQAKYSTIDFDFLGYAVVRFNQYFKMKLEVMMLTLPE", "length": 363, "header": "tr|F1NMC4-1|F1NMC4_CHICK Isoform 1 of ethanolamine kinase OS=Gallus gallus OX=9031 GN=ETNK1 PE=3 SV=2 CANONICAL=F1NMC4-1" }, "isoforms": [ { "isoform_ac": "F1NMC4-1", "url": "https://www.uniprot.org/uniprotkb/F1NMC4/entry#F1NMC4-1", "sequence": { "sequence": "MSNYIHVPPGSPEVPKLDITVSEREGPGCRQGALQLLRRLRPHWRPEEVTLQLFTDGITNKLIGCYVGDTTDDVVLVRIYGNKTELLVDRDEEVKSFRVLQAHGCAPQLYCTFNNGLCYEFMQGEALDPEHVCNPDIFRLIARQLAKIHTIHAHNGWIPKSNLWLKMGKYFSLIPTEFADEEVNKRFLSEIPSPQVLQEEMAWMKERLSNLGSPVVLCHNDLLCKNIIYNKKRGDVQFIDYEYSGYNYLAYDIGNHFNEFAGVNEVDYSLYPNRKLQEQWLRSYLEAYKEYKGFGTEVSEKEVEVLYVQVNQFALASHFFWGLWALIQAKYSTIDFDFLGYAVVRFNQYFKMKLEVMMLTLPE", "length": 363, "header": "tr|F1NMC4-1|F1NMC4_CHICK Isoform 1 of ethanolamine kinase OS=Gallus gallus OX=9031 GN=ETNK1 PE=3 SV=2 CANONICAL=F1NMC4-1" }, "locus": { "chromosome": "1", "start_pos": 66531283, "end_pos": 66505396, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034858.1", "url": "https://www.ensembl.org/id/ENSGALT00010034858.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020414.1", "url": "https://www.ensembl.org/id/ENSGALP00010020414.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "gga:418196", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418196", "resource": "KEGG Pathway" }, { "id": "R-GGA-1483213", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1483213", "resource": "Reactome", "description": "Synthesis of PE" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A5G2QF92-1", "protein_name": "ethanolamine kinase", "gene_name": "ETNK1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MANYIHVPPGSPEVPKLNVTVQDQEEQRCREGALSLLQHLRPHWDPQEVTLQLFTDGITNKLIGCYVGNTMEDVVLVRIYGNKTELLVDREEEVKSFRVLQAHGCAPQLYCTFNNGLCYEFIQGEALDPKHVCNPAIFRLIARQLAKIHAIHAHNGWIPKSNLWLKMGKYFSLIPTGFVDEDINKRFLSDIPSPQILQEEMTWMKDILSNLGSPVVLCHNDLLCKNIIYNEKQGDVQFIDYEYSGYNYLAYDIGNHFNEFAGVSDVDYSLYPSRELQGQWLRSYLEAYKEYKGFGTEVTEKEVEILFIQVNQFALASHFFWGLWALIQAKYSTIDFDFLGYAIVRFNQYFKMKPEVTALKVPE", "length": 363 }, "evidence": [ { "id": "F1NMC4", "url": "https://omabrowser.org/oma/group/F1NMC4/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0ABK0LLY9-1", "protein_name": "ethanolamine kinase", "gene_name": "Etnk1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MANYIHVPPGSPEVPKLDVTVQDQEEQRCRDGALSLLQHLRPHWDPREVTLQLFTDGITNKLIACYVGDTMDDVVLVRIYGNKTELLVDRDEEVKSFRVLQAHGCAPQLYCTFNNGLCYEFIQGEALDPQHVCNPAIFRLIARQLAKIHAIHAHNGWIPKSNLWLKMGKYFSLIPTGFADEDINKRFLSEIPSPQLLQEEMTWMKEILSSLGSPVVLCHNDLLCKNIIYNEKQGDVQFIDYEYSGYNYLAYDIGNHFNEFAGVSDVDYSLYPDRELQGQWLRSYLEAYKEYKGFGSDVTEKEVETLFIQVNQFALASHFFWGLWALIQAKYSTIEFDFLGYAIVRFNQYFKMKPEVTALKMPE", "length": 363 }, "evidence": [ { "id": "F1NMC4", "url": "https://omabrowser.org/oma/group/F1NMC4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P54352-2", "protein_name": "Ethanolamine kinase", "gene_name": "eas", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MGTETKSNSYTGQISTSGGNPKVMKDSLSLVRQTVNQQTLSLSQSNQVQNQLNSHSNSNSYPNPSGSENKNENEQNSRDIRAKPEDKSRKEAIVPFVPIFVEEADVIQGAKELLKVIRPTWDLSHVEFKSFTDGITNKLVGCFHKEISKLNDENGGSYLPIKTQGLSPVQSEDPVIIEKEDDDEFTDDRAADDGSPVQYSDNVVLVRIYGNKTDLLIDRKAETQNFLLLHTYGLAPSLYATFKNGLVYEYVPGTTLNTDSVLCPEIWPLVARRMAEMHRKVRKHGDSSATKPMPMIWKKTQSFLDLVPERFSDAEKHKRVKETFLPIGRLREEFNKLYEYLEALDSPIVFSHNDLLLGNVIYTQSLNTVNFIDYEYADYNFQAFDIGNHFAEMCGVDEVDYSRYPKREFQLQWLRVYLEEYLQRSNIQNDEVELLYVQVNQFALASHIFWTVWSLLQAEHSTIDFDYVGYAFLRYNEYLARKVEFLSLTAAKNNK", "length": 495 }, "evidence": [ { "id": "F1NMC4", "url": "https://omabrowser.org/oma/group/F1NMC4/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q5RGY0-1", "protein_name": "ethanolamine kinase", "gene_name": "etnk1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MANYIHVPDGSPAVPKLDVTVDEHDYRAGALKLIKTLRPHWKPSEVKMKTFTDGITNKLIGCYVGGSMQEVVLVRVYGNKTELFVDRENEVKSFRVLQAHRCAPRLYCTFNNGLCYEFLQGVALEPEHIRSPAIFRHIARQMAKYHAIHAHNGWVPQSGLWLKMSKFFSLVPSHFEDPEMDQRLNNEVPSAACLRDEMIWLQQNLSKLGSPVVLCHNDLLCKNIIYNQKEGNVKFIDYEYAGYNYQAFDIGNHFNEFAGLNEVDYTLYPDRELQMQWLRAYLEAYKEYKSQGSQVSNTEVELLYVQVNRFALASHFFWGLWALIQAQYSTIDFDFLGYAVLRFNQYFKMKPEVMSLHLPE", "length": 360 }, "evidence": [ { "id": "F1NMC4", "url": "https://omabrowser.org/oma/group/F1NMC4/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q8L518-1", "protein_name": "Probable choline kinase 2", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MTMGGTEKNVENKQYRLPREVKEALQAIASEWEDVIDSKALQVIPLKGAMTNEVFQIKWPTREKGPSRKVLVRIYGEGVEIFFDREDEIRTFEFMSKHGHGPLLLGRFGNGRIEEFLHARTLSACDLRDPEISGRIATRMKEFHGLEMPGAKKALLWDRLRNWLTACKRLASPEEAKSFRLDVMEMEINMLEKSLFDNDENIGFCHNDLQYGNIMMDEETKAITIIDYEYSCYNPVAYDIANHFCEMAADYHTETPHIMDYSKYPGVEERQRFLKTYMSYSDEKPSDTMVKKLLEDVEKYTLASHLIWGLWGIISEHVNEIDFDYMEYARQRFEQYWLTKPRLLAASEHK", "length": 350 }, "evidence": [ { "id": "F1NMC4", "url": "https://omabrowser.org/oma/group/F1NMC4/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9D4V0-1", "protein_name": "Ethanolamine kinase 1", "gene_name": "Etnk1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MANYIHVPPGSPEVPKLDVTVQDQEEQRCRDGALSLLRHLRPHWDPREVTLQLFTDGITNKLIACYVGDTMEDVVLVRIYGNKTELLVDRDEEVKSFRVLQAHGCAPQLYCTFNNGLCYEFIQGEALDPQHVCNPAIFRLIARQLAKIHAIHAHNGWIPKSNLWLKMGKYFSLIPTGFADENINKRFLSEIPSPQLLQEEMTWMKELLSSLGSPVVLCHNDLLCKNIIYNEKQGDVQFIDYEYSGYNYLAYDIGNHFNEFAGVSDVDYSLYPDRELQGQWLRSYLEAYKEYKGFGSDVTEKEVETLFIQVNQFALASHFFWGLWALIQAKYSTIEFDFLGYAVVRFNQYFKMKPEVTALKMPE", "length": 363 }, "evidence": [ { "id": "F1NMC4", "url": "https://omabrowser.org/oma/group/F1NMC4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9HBU6-1", "protein_name": "Ethanolamine kinase 1", "gene_name": "ETNK1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLCGRPRSSSDNRNFLRERAGLSSAAVQTRIGNSAASRRSPAARPPVPAPPALPRGRPGTEGSTSLSAPAVLVVAVAVVVVVVSAVAWAMANYIHVPPGSPEVPKLNVTVQDQEEHRCREGALSLLQHLRPHWDPQEVTLQLFTDGITNKLIGCYVGNTMEDVVLVRIYGNKTELLVDRDEEVKSFRVLQAHGCAPQLYCTFNNGLCYEFIQGEALDPKHVCNPAIFRLIARQLAKIHAIHAHNGWIPKSNLWLKMGKYFSLIPTGFADEDINKRFLSDIPSSQILQEEMTWMKEILSNLGSPVVLCHNDLLCKNIIYNEKQGDVQFIDYEYSGYNYLAYDIGNHFNEFAGVSDVDYSLYPDRELQSQWLRAYLEAYKEFKGFGTEVTEKEVEILFIQVNQFALASHFFWGLWALIQAKYSTIEFDFLGYAIVRFNQYFKMKPEVTALKVPE", "length": 452 }, "evidence": [ { "id": "F1NMC4", "url": "https://omabrowser.org/oma/group/F1NMC4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "F1NMC4", "url": "https://www.uniprot.org/uniprotkb/F1NMC4" } ], "pmid": "" }, { "name": "ethanolamine kinase activity", "id": "GO:0004305", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004305", "evidence": [ { "database": "UniProtKB", "id": "F1NMC4", "url": "https://www.uniprot.org/uniprotkb/F1NMC4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1NMC4", "url": "https://www.uniprot.org/uniprotkb/F1NMC4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "phosphatidylethanolamine biosynthetic process", "id": "GO:0006646", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006646", "evidence": [ { "database": "UniProtKB", "id": "F1NMC4", "url": "https://www.uniprot.org/uniprotkb/F1NMC4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 82, "end_pos": 84, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-GGA-1483222", "name": "ETA is phosphorylated to PETA by CHK/ETNK", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [ "R-ALL-1498751" ], "output_participant_list": [], "enzyme_list": [ "F1NL82-1", "F1NMC4-1", "A0A1D5P2G3-1" ], "evidence": [ { "id": "R-GGA-1483222", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1483222" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-1498751", "participant_name": "ETA [cytosol]", "crossref": [ { "id": "57603", "database": "ChEBI", "url": "" }, { "id": "ZINC000008214617", "database": "ZINC", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A0A1D5P2G3", "gene_name": "CHKA", "activity": [ { "ec_number": "2.7.1.32", "activity": "choline + ATP = phosphocholine + ADP + H(+).", "evidence": [ { "id": "A0A1D5P2G3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P2G3" } ] }, { "ec_number": "2.7.1.82", "activity": "ethanolamine + ATP = phosphoethanolamine + ADP + H(+).", "evidence": [ { "id": "A0A1D5P2G3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P2G3" } ] }, { "ec_number": "2.7.1.82", "activity": "", "evidence": [ { "id": "A0A1D5P2G3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P2G3" } ] }, { "ec_number": "2.7.1.32", "activity": "", "evidence": [ { "id": "A0A1D5P2G3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P2G3" } ] } ] }, { "uniprot_ac": "F1NL82", "gene_name": "ETNK2", "activity": [ { "ec_number": "2.7.1.82", "activity": "ethanolamine + ATP = phosphoethanolamine + ADP + H(+).", "evidence": [ { "id": "F1NL82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NL82" } ] }, { "ec_number": "2.7.1.82", "activity": "", "evidence": [ { "id": "F1NL82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NL82" } ] } ] }, { "uniprot_ac": "F1NMC4", "gene_name": "ETNK1", "activity": [ { "ec_number": "2.7.1.82", "activity": "ethanolamine + ATP = phosphoethanolamine + ADP + H(+).", "evidence": [ { "id": "F1NMC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NMC4" } ] }, { "ec_number": "2.7.1.82", "activity": "", "evidence": [ { "id": "F1NMC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NMC4" } ] } ] } ], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1NMC4-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 363, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1NMC4-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1NMC4" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.7.1.82", "ec_name": "ethanolamine + ATP = phosphoethanolamine + ADP + H(+).", "evidence": [ { "id": "2.7.1.82", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.82" }, { "id": "2.7.1.82", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.7.1.82" } ] } ], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 82, "end_pos": 84 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1NMK6-1", "uniprot_ac": "F1NMK6", "uniprot_id": "F1NMK6_CHICK", "mass": { "chemical_mass": 43106.0, "monoisotopic_mass": 43106.0 }, "refseq": { "ac": "XP_015141287", "name": "protein Wnt-5b isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015141287" }, "gene_names": [ { "name": "WNT5B", "type": "recommended", "evidence": [ { "id": "F1NMK6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NMK6" } ] }, { "name": "WNT5B", "type": "synonym", "evidence": [ { "id": "XP_015141287", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015141287" } ] } ], "protein_names": [ { "name": "Protein Wnt", "type": "recommended", "evidence": [ { "id": "F1NMK6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NMK6/entry#names_and_taxonomy" } ] }, { "name": "protein Wnt-5b isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015141287", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015141287" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015141287", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015141287" } ] }, { "annotation": "Ligand for members of the frizzled family of seven transmembrane receptors.", "evidence": [ { "database": "UniProtKB", "id": "F1NMK6", "url": "https://www.uniprot.org/uniprotkb/F1NMK6#function" }, { "database": "UniProtKB", "id": "RU003500", "url": "https://www.uniprot.org/uniprotkb/RU003500#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NMK6", "url": "https://www.uniprot.org/uniprotkb/F1NMK6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "WNT5B", "url": "https://www.uniprot.org/uniprotkb/F1NMK6", "locus": { "chromosome": "1", "start_pos": 60976792, "end_pos": 60910921, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013899", "url": "https://www.ensembl.org/id/ENSGALG00010013899" } ] } } ], "crossref": [ { "id": "F1NMK6", "url": "https://alphafold.ebi.ac.uk/entry/F1NMK6", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000012998", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000012998", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd19348", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd19348", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "418154", "url": "https://www.ncbi.nlm.nih.gov/gene/418154", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR005817", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005817", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018161", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018161", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043158", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043158", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IQVERCH", "url": "https://omabrowser.org/oma/group/IQVERCH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1NMK6", "url": "https://www.orthodb.org/?gene=F1NMK6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12027", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12027", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12027:SF87", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12027:SF87", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00110", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00110", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-3238698", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3238698", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_015141287", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015141287", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1NMK6", "url": "https://www.uniprot.org/uniprotkb/F1NMK6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NMK6-1", "url": "https://www.uniprot.org/uniprotkb/F1NMK6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQGAPCRRPPPRGLPQRRRRPQPTMTGPRLALAAALLCSCTSPVADANSWWSLAMNPIQRPEMYIIGAQPVCSQLPGLSPGQRKLCQLYQEHMVFIGEGARSAIKECQYQFRQRRWNCSTVDNTSVFGRVMKIGSRETAFTYAVSAAGVVNAISRACREGELSSCGCSRTARPKDLPRDWLWGGCGDNVEYGYRFAKEFVDAKEREKNYVRGSEEQARMLMNLQNNEAGRRAVYKLADVACKCHGVSGSCSLKTCWLQLADFRKVGDLLKEKYDSAAAMRISRKGKLELVNNRFNMPTQEDLVYVDPSPDYCLRNETTGSLGTQGRLCNKTSEGMDGCELMCCGRGYDQFKSVQVERCHCKFHWCCYVKCKKCTEIVDQYVCK", "length": 383, "header": "tr|F1NMK6-1|F1NMK6_CHICK Isoform 1 of Protein Wnt OS=Gallus gallus OX=9031 GN=WNT5B PE=3 SV=4 CANONICAL=F1NMK6-1" }, "isoforms": [ { "isoform_ac": "F1NMK6-1", "url": "https://www.uniprot.org/uniprotkb/F1NMK6/entry#F1NMK6-1", "sequence": { "sequence": "MQGAPCRRPPPRGLPQRRRRPQPTMTGPRLALAAALLCSCTSPVADANSWWSLAMNPIQRPEMYIIGAQPVCSQLPGLSPGQRKLCQLYQEHMVFIGEGARSAIKECQYQFRQRRWNCSTVDNTSVFGRVMKIGSRETAFTYAVSAAGVVNAISRACREGELSSCGCSRTARPKDLPRDWLWGGCGDNVEYGYRFAKEFVDAKEREKNYVRGSEEQARMLMNLQNNEAGRRAVYKLADVACKCHGVSGSCSLKTCWLQLADFRKVGDLLKEKYDSAAAMRISRKGKLELVNNRFNMPTQEDLVYVDPSPDYCLRNETTGSLGTQGRLCNKTSEGMDGCELMCCGRGYDQFKSVQVERCHCKFHWCCYVKCKKCTEIVDQYVCK", "length": 383, "header": "tr|F1NMK6-1|F1NMK6_CHICK Isoform 1 of Protein Wnt OS=Gallus gallus OX=9031 GN=WNT5B PE=3 SV=4 CANONICAL=F1NMK6-1" }, "locus": { "chromosome": "1", "start_pos": 60975790, "end_pos": 60911221, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033322.1", "url": "https://www.ensembl.org/id/ENSGALT00010033322.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019666.1", "url": "https://www.ensembl.org/id/ENSGALP00010019666.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-3238698", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3238698", "resource": "Reactome", "description": "WNT ligand biogenesis and trafficking" } ], "orthologs": [ { "uniprot_canonical_ac": "A0AAA9TGT5-1", "protein_name": "Protein Wnt", "gene_name": "WNT5B", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MARCMMPVSLMLSHERRLRLRRLPMCDRCRSPASEMPPQKLRLRSLRPVSPREMCFRDREPHLGSRRSPGSSPALGGAGRRRTMPSLPALLALLFACWAPLRATASSWWSLAMSPVQRPEMFIIGAQPVCSQLPGLSAGQRKLCQLYQEHMAYIGEGARTGIRECQHQFRQRRWNCSTVDDASVFGRVLQIGSRETAFTYAVSAAGVVNAISRACREGELSTCGCSRAARPKDLPRDWLWGGCGDNVDYGYRFAKEFVDAREREKNFAKGSEEQGRVLMNLQNNEAGRRAVYKTADVACKCHGVSGSCSLKTCWLQLAEFRKVGDQLKEKYDSAAAMRITRRGKLELVNSRFKPPTPEDLVYVDPSPDYCLRDESTGSLGTRGRLCNKTSEGLDGCALMCCGRGYNQFKSVRTERCHCKFHWCCFVRCKKCTQVVDQFVCK", "length": 441 }, "evidence": [ { "id": "F1NMK6", "url": "https://omabrowser.org/oma/group/F1NMK6/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0ABK0M064-1", "protein_name": "Protein Wnt", "gene_name": "Wnt5b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAKCMMPVSLMLSQERRLRLRRLPMCDRCRRPASEIPPQKLRLRSLRPVSPREMCFRERSGAPLWKMLVPGHWDGLRPAMPSLLLLFVAALLSSWAQLLTDANSWWSLALNPVQRPEMFIIGAQPVCSQLPGLSPGQRKLCQLYQEHMSYIGEGAKTGIRECQHQFRQRRWNCSTVDNLSVFGRVMQIGSRETAFTYAVSAAGVVNAISRACREGELSTCGCSRAARPKDLPRDWLWGGCGDNVEYGYRFAKEFVDAREREKNFAKGSEEQGRALMNLQNNEAGRRAVYKMADVSCKCHGVSGSCSLKTCWLQLAEFRKVGDRLKEKYDSAAAMRITRQGKLELTNSRFNQPSPEDLVYVDPSPDYCLRNETTGSLGTQGRLCNKTSEGTDGCELMCCGRGYDRFKSVQVERCHCRFHWCCFVRCKKCTEIVDQYVCK", "length": 438 }, "evidence": [ { "id": "F1NMK6", "url": "https://omabrowser.org/oma/group/F1NMK6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P22726-1", "protein_name": "Protein Wnt-5b", "gene_name": "Wnt5b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPSLLLVVVAALLSSWAQLLTDANSWWSLALNPVQRPEMFIIGAQPVCSQLPGLSPGQRKLCQLYQEHMSYIGEGAKTGIRECQHQFRQRRWNCSTVDNTSVFGRVMQIGSRETAFTYAVSAAGVVNAISRACREGELSTCGCSRAARPKDLPRDWLWGGCGDNVEYGYRFAKEFVDAREREKNFAKGSEEQGRALMNLQNNEAGRRAVYKMADVACKCHGVSGSCSLKTCWLQLAEFRKVGDRLKEKYDSAAAMRITRQGKLELANSRFNQPTPEDLVYVDPSPDYCLRNETTGSLGTQGRLCNKTSEGMDGCELMCCGRGYDRFKSVQVERCHCRFHWCCFVRCKKCTEVVDQYVCK", "length": 359 }, "evidence": [ { "id": "F1NMK6", "url": "https://omabrowser.org/oma/group/F1NMK6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q92050-1", "protein_name": "Protein Wnt-5b", "gene_name": "wnt5b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDVRMNQGHLLLAVTLIVCNSQLLVVANSWWSLAMNPIQRPEMYIIGAQPLCSQLTGLSQGQRKLCQLYQDHMVYIGEGAKTGIKECQYQFRQRRWNCSTVDNTSVFGRVMHIGSRETAFTYAVSAAGVVNAVSRACREGELSTCGCSRAARPRDLPRDWLWGGCGDNVNYGYRFAREFVDAREREKNYPRGSVEHARTLMNLQNNEAGRMAVYNLANVACKCHGVSGSCSLKTCWLQLADFRRVGEFLKEKYDSAAAMRINRRGKLELVNNRFNPPTGEDLVYIDPSPDYCLRNETTGSLGTQGRLCNKTSEGMDGCELMCCGRGYDQFKTYKHERCHCKFHWCCYVKCKRCTSLVDQFVCK", "length": 363 }, "evidence": [ { "id": "F1NMK6", "url": "https://omabrowser.org/oma/group/F1NMK6/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q9H1J7-1", "protein_name": "Protein Wnt-5b", "gene_name": "WNT5B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPSLLLLFTAALLSSWAQLLTDANSWWSLALNPVQRPEMFIIGAQPVCSQLPGLSPGQRKLCQLYQEHMAYIGEGAKTGIKECQHQFRQRRWNCSTADNASVFGRVMQIGSRETAFTHAVSAAGVVNAISRACREGELSTCGCSRTARPKDLPRDWLWGGCGDNVEYGYRFAKEFVDAREREKNFAKGSEEQGRVLMNLQNNEAGRRAVYKMADVACKCHGVSGSCSLKTCWLQLAEFRKVGDRLKEKYDSAAAMRVTRKGRLELVNSRFTQPTPEDLVYVDPSPDYCLRNESTGSLGTQGRLCNKTSEGMDGCELMCCGRGYNQFKSVQVERCHCKFHWCCFVRCKKCTEIVDQYICK", "length": 359 }, "evidence": [ { "id": "F1NMK6", "url": "https://omabrowser.org/oma/group/F1NMK6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "frizzled binding", "id": "GO:0005109", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005109", "evidence": [ { "database": "UniProtKB", "id": "F1NMK6", "url": "https://www.uniprot.org/uniprotkb/F1NMK6" } ], "pmid": "" }, { "name": "cytokine activity", "id": "GO:0005125", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005125", "evidence": [ { "database": "UniProtKB", "id": "F1NMK6", "url": "https://www.uniprot.org/uniprotkb/F1NMK6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "F1NMK6", "url": "https://www.uniprot.org/uniprotkb/F1NMK6" } ], "pmid": "" }, { "name": "cell surface", "id": "GO:0009986", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009986", "evidence": [ { "database": "UniProtKB", "id": "F1NMK6", "url": "https://www.uniprot.org/uniprotkb/F1NMK6" } ], "pmid": "" }, { "name": "extracellular matrix", "id": "GO:0031012", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031012", "evidence": [ { "database": "UniProtKB", "id": "F1NMK6", "url": "https://www.uniprot.org/uniprotkb/F1NMK6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "positive regulation of cell migration", "id": "GO:0030335", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030335", "evidence": [ { "database": "UniProtKB", "id": "F1NMK6", "url": "https://www.uniprot.org/uniprotkb/F1NMK6" } ], "pmid": "" }, { "name": "neuron differentiation", "id": "GO:0030182", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030182", "evidence": [ { "database": "UniProtKB", "id": "F1NMK6", "url": "https://www.uniprot.org/uniprotkb/F1NMK6" } ], "pmid": "" }, { "name": "canonical Wnt signaling pathway", "id": "GO:0060070", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060070", "evidence": [ { "database": "UniProtKB", "id": "F1NMK6", "url": "https://www.uniprot.org/uniprotkb/F1NMK6" } ], "pmid": "" }, { "name": "chondrocyte differentiation", "id": "GO:0002062", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002062", "evidence": [ { "database": "UniProtKB", "id": "F1NMK6", "url": "https://www.uniprot.org/uniprotkb/F1NMK6" } ], "pmid": "" }, { "name": "cell fate commitment", "id": "GO:0045165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045165", "evidence": [ { "database": "UniProtKB", "id": "F1NMK6", "url": "https://www.uniprot.org/uniprotkb/F1NMK6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 117, "end_pos": 119, "annotation": "n_glycosylation_sequon" }, { "start_pos": 123, "end_pos": 125, "annotation": "n_glycosylation_sequon" }, { "start_pos": 315, "end_pos": 317, "annotation": "n_glycosylation_sequon" }, { "start_pos": 329, "end_pos": 331, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1NMK6-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 383, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1NMK6-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1NMK6" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 117, "end_pos": 119 }, { "start_pos": 123, "end_pos": 125 }, { "start_pos": 315, "end_pos": 317 }, { "start_pos": 329, "end_pos": 331 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { 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"count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1NML7-1", "uniprot_ac": "F1NML7", "uniprot_id": "F1NML7_CHICK", "mass": { "chemical_mass": 58604.0, "monoisotopic_mass": 58604.0 }, "refseq": { "ac": "XP_015141316", "name": "adenosine deaminase 2 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015141316" }, "gene_names": [ { "name": "CECR1", "type": "recommended", "evidence": [ { "id": "F1NML7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NML7" } ] }, { "name": "ADA2", "type": "synonym", "evidence": [ { "id": "XP_015141316", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015141316" } ] }, { "name": "CECR1", "type": "synonym", "evidence": [ { "id": "XP_015141316", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015141316" } ] } ], "protein_names": [ { "name": "adenosine deaminase", "type": "recommended", "evidence": [ { "id": "F1NML7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NML7/entry#names_and_taxonomy" } ] }, { "name": "3.5.4.4", "type": "synonym", "evidence": [ { "id": "F1NML7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NML7/entry#names_and_taxonomy" } ] }, { "name": "adenosine deaminase 2 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015141316", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015141316" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015141316", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015141316" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NML7", "url": "https://www.uniprot.org/uniprotkb/F1NML7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CECR1", "url": "https://www.uniprot.org/uniprotkb/F1NML7", "locus": { "chromosome": "1", "start_pos": 61711482, "end_pos": 61730279, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010011860", "url": "https://www.ensembl.org/id/ENSGALG00010011860" } ] } } ], "crossref": [ { "id": "F1NML7", "url": "https://alphafold.ebi.ac.uk/entry/F1NML7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000013031", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000013031", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd01321", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01321", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "418160", "url": "https://www.ncbi.nlm.nih.gov/gene/418160", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001365", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001365", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006330", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006330", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006331", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006331", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013659", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013659", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032466", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032466", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "SMKQCIE", "url": "https://omabrowser.org/oma/group/SMKQCIE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YEW0", "url": "https://www.orthodb.org/?gene=A0A8V0YEW0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NML7", "url": "https://www.orthodb.org/?gene=F1NML7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11409", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11409", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11409:SF39", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11409:SF39", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00962", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00962", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08451", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08451", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-5683826", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5683826", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-6798695", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6798695", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_015141316", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015141316", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "24408", "url": "https://www.rhea-db.org/rhea/24408", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YEW0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEW0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YEW0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEW0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NML7", "url": "https://www.uniprot.org/uniprotkb/F1NML7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NML7-1", "url": "https://www.uniprot.org/uniprotkb/F1NML7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MCRSKMKPPSGQGIRLACLLGLASLCLPTPLWEDRDSLMQEEEARLTGGNLVLSTQEQQLSMKLISLKKKEVAAALNTGQFPPSMHFFRAKSLIEQSAVFSILKRMPKGAVLHLHDYAMLSVDWLVYNATYLPDCYICFTQTGTVRFRFSKPHPPHPVPAQCSQWVLLETYRKQLRNVTEFDHSLLRNLTLVTDAPELAYPSQAFIWKRFEEVFLIASGLICYAPVFKAYFYQGLLELYEDNIQYVEIRAILPAVYELDGTQHNKSWSVAAYQEVSRRFVQEHPDFLGAKVIFAAHRMLNVSQIKETIITAMELRAHFPDTLAGFDLVGNEDEGHSLWEFKDVLTIPYSLRANLPYFFHAGETDWQGTSVDNNVLDALLLNTSRIGHGLALTKHPVAKNLSLKRDIPVEVCPISNQVLLLVSDLRSHPAASLMAEGHPVVVSPDDPSIFGAKGVSYDFYEVFMAIGGMNADLRTLKQLALNSIKYSAMLLDEKAKAREVWQKKWDQFVADLTDSSLMEL", "length": 519, "header": "tr|F1NML7-1|F1NML7_CHICK Isoform 1 of adenosine deaminase OS=Gallus gallus OX=9031 GN=CECR1 PE=1 SV=3 CANONICAL=F1NML7-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YEW0-1", "url": "https://www.uniprot.org/uniprotkb/F1NML7/entry#A0A8V0YEW0-1", "sequence": { "sequence": "MKPPSGQGIRLACLLGLASLCLPTPLWEDRDSLMQEEEARLTGGNLVLSTQEQQLSMKLISLKKKEVAAALNTGQFPPSMHFFRAKSLIEQSAVFSILKRMPKGAVLHLHDYAMLSVDWLVYNATYLPDCYICFTQTGTVRFRFSKPHPPHPVPAQCSQWVLLETYRKQLRNVTEFDHSLLRNLTLVTDAPELAYPSQAFIWKRFEEVFLIASGLICYAPVFKAYFYQGLLELYEDNIQYVEIRAILPAVYELDGTQHNKSWSVAAYQEVSRRFVQEHPDFLGAKVIFAAHRMLNVSQIKETIITAMELRAHFPDTLAGFDLVGNEDEGHSLWEFKDVLTIPYSLRANLPYFFHAGETDWQGTSVDNNVLDALLLNTSRIGHGLALTKHPVAKNLSLKRDIPVEVCPISNQVLLLVSDLRSHPAASLMAEGHPVVVSPDDPSIFGAKGVSYDFYEVFMAIGGMNADLRTLKQLALNSIKQL", "length": 481, "header": "tr|A0A8V0YEW0-1|A0A8V0YEW0_CHICK Computationally mapped isoform of adenosine deaminase OS=Gallus gallus OX=9031 GN=CECR1 PE=1 SV=1 CANONICAL=F1NML7-1" }, "locus": { "chromosome": "1", "start_pos": 61729283, "end_pos": 61714900, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028337.1", "url": "https://www.ensembl.org/id/ENSGALT00010028337.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016238.1", "url": "https://www.ensembl.org/id/ENSGALP00010016238.1" } ] } }, { "isoform_ac": "F1NML7-1", "url": "https://www.uniprot.org/uniprotkb/F1NML7/entry#F1NML7-1", "sequence": { "sequence": "MCRSKMKPPSGQGIRLACLLGLASLCLPTPLWEDRDSLMQEEEARLTGGNLVLSTQEQQLSMKLISLKKKEVAAALNTGQFPPSMHFFRAKSLIEQSAVFSILKRMPKGAVLHLHDYAMLSVDWLVYNATYLPDCYICFTQTGTVRFRFSKPHPPHPVPAQCSQWVLLETYRKQLRNVTEFDHSLLRNLTLVTDAPELAYPSQAFIWKRFEEVFLIASGLICYAPVFKAYFYQGLLELYEDNIQYVEIRAILPAVYELDGTQHNKSWSVAAYQEVSRRFVQEHPDFLGAKVIFAAHRMLNVSQIKETIITAMELRAHFPDTLAGFDLVGNEDEGHSLWEFKDVLTIPYSLRANLPYFFHAGETDWQGTSVDNNVLDALLLNTSRIGHGLALTKHPVAKNLSLKRDIPVEVCPISNQVLLLVSDLRSHPAASLMAEGHPVVVSPDDPSIFGAKGVSYDFYEVFMAIGGMNADLRTLKQLALNSIKYSAMLLDEKAKAREVWQKKWDQFVADLTDSSLMEL", "length": 519, "header": "tr|F1NML7-1|F1NML7_CHICK Isoform 1 of adenosine deaminase OS=Gallus gallus OX=9031 GN=CECR1 PE=1 SV=3 CANONICAL=F1NML7-1" }, "locus": { "chromosome": "1", "start_pos": 61729473, "end_pos": 61714360, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028327.1", "url": "https://www.ensembl.org/id/ENSGALT00010028327.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016229.1", "url": "https://www.ensembl.org/id/ENSGALP00010016229.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "R-GGA-5683826", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5683826", "resource": "Reactome", "description": "Surfactant metabolism" }, { "id": "R-GGA-6798695", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6798695", "resource": "Reactome", "description": "Neutrophil degranulation" } ], "orthologs": [ { "uniprot_canonical_ac": "Q553U5-1", "protein_name": "Adenosine deaminase 2", "gene_name": "ADA2", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MFLKFKNIFFIVLTLSIVFNGLIVNSKNIHINNKNNNNNNNNKDLSSSESGSSSDINPYISQYNSERETLVNQENQIKLGSNTPFNSKEQQANTIFLNILQNEELSFSNNDPSGVNFFIEKQIIENESTIFKIIQNMPKGSALHVHQDSSATYDYLISVGSYLPNCYIYLTYDVNDANNGTFHFYDSQPTDSNWKLLSTIREGVSNVESFDQQLLDSLTLIGQDYGDYVSLWRKFDGIFGRVNGLVTYLPIATGYMEHLFQQMIQDGVQHIEVRKCFGDFYDLTGKIYDDYWFVQTMEELVLTTRQKYNMSEFALKIIGCNGRHNNQSVVYDAMVMSLDLRNKYPSTFVGYDLVGPEDEGYPLIYFIEQFAEIKKLGYQYQYPLDYYFHAGETILYNNTNLYDAILLNTKRIGHGIQLPKHPLLMDLVLKNDIGIEICPISNQILQYVSDMRAHPGLDLLNRGLPVTISPDDPAIFNYGGLSYDFFELTYSWGLNLQQLKQLAINSINHSNTFNQSEYNLLYNAWEVKWFNFIDYIINTYSNI", "length": 543 }, "evidence": [ { "id": "F1NML7", "url": "https://omabrowser.org/oma/group/F1NML7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q9NZK5-1", "protein_name": "Adenosine deaminase 2", "gene_name": "ADA2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLVDGPSERPALCFLLLAVAMSFFGSALSIDETRAHLLLKEKMMRLGGRLVLNTKEELANERLMTLKIAEMKEAMRTLIFPPSMHFFQAKHLIERSQVFNILRMMPKGAALHLHDIGIVTMDWLVRNVTYRPHCHICFTPRGIMQFRFAHPTPRPSEKCSKWILLEDYRKRVQNVTEFDDSLLRNFTLVTQHPEVIYTNQNVVWSKFETIFFTISGLIHYAPVFRDYVFRSMQEFYEDNVLYMEIRARLLPVYELSGEHHDEEWSVKTYQEVAQKFVETHPEFIGIKIIYSDHRSKDVAVIAESIRMAMGLRIKFPTVVAGFDLVGHEDTGHSLHDYKEALMIPAKDGVKLPYFFHAGETDWQGTSIDRNILDALMLNTTRIGHGFALSKHPAVRTYSWKKDIPIEVCPISNQVLKLVSDLRNHPVATLMATGHPMVISSDDPAMFGAKGLSYDFYEVFMGIGGMKADLRTLKQLAMNSIKYSTLLESEKNTFMEIWKKRWDKFIADVATK", "length": 511 }, "evidence": [ { "id": "F1NML7", "url": "https://omabrowser.org/oma/group/F1NML7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 6, "go_terms": [ { "name": "adenosine deaminase activity", "id": "GO:0004000", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004000", "evidence": [ { "database": "UniProtKB", "id": "F1NML7", "url": "https://www.uniprot.org/uniprotkb/F1NML7" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "F1NML7", "url": "https://www.uniprot.org/uniprotkb/F1NML7" } ], "pmid": "" }, { "name": "protein homodimerization activity", "id": "GO:0042803", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042803", "evidence": [ { "database": "UniProtKB", "id": "F1NML7", "url": "https://www.uniprot.org/uniprotkb/F1NML7" } ], "pmid": "" }, { "name": "adenosine receptor binding", "id": "GO:0031685", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031685", "evidence": [ { "database": "UniProtKB", "id": "F1NML7", "url": "https://www.uniprot.org/uniprotkb/F1NML7" } ], "pmid": "" }, { "name": "proteoglycan binding", "id": "GO:0043394", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043394", "evidence": [ { "database": "UniProtKB", "id": "F1NML7", "url": "https://www.uniprot.org/uniprotkb/F1NML7" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "F1NML7", "url": "https://www.uniprot.org/uniprotkb/F1NML7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "F1NML7", "url": "https://www.uniprot.org/uniprotkb/F1NML7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "adenosine catabolic process", "id": "GO:0006154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006154", "evidence": [ { "database": "UniProtKB", "id": "F1NML7", "url": "https://www.uniprot.org/uniprotkb/F1NML7" } ], "pmid": "" }, { "name": "inosine biosynthetic process", "id": "GO:0046103", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046103", "evidence": [ { "database": "UniProtKB", "id": "F1NML7", "url": "https://www.uniprot.org/uniprotkb/F1NML7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 128, "end_pos": 130, "annotation": "n_glycosylation_sequon" }, { "start_pos": 177, "end_pos": 179, "annotation": "n_glycosylation_sequon" }, { "start_pos": 188, "end_pos": 190, "annotation": "n_glycosylation_sequon" }, { "start_pos": 264, "end_pos": 266, "annotation": "n_glycosylation_sequon" }, { "start_pos": 300, "end_pos": 302, "annotation": "n_glycosylation_sequon" }, { "start_pos": 381, "end_pos": 383, "annotation": "n_glycosylation_sequon" }, { "start_pos": 399, "end_pos": 401, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "24408", "name": "", "equation": "adenosine + H2O + H(+) = inosine + NH4(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A3Q2UAL7-1", "Q5ZKP6-1", "P84520-1", "A0A8V0ZWX9-1", "F1NML7-1" ], "evidence": [ { "id": "24408", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/24408" } ] }, { "id": "R-GGA-5693346", "name": "CECRI deaminates Ade-Rib to Ino", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "extracellular region", "input_participant_list": [ "R-ALL-83908" ], "output_participant_list": [ "R-ALL-2022135", "R-ALL-83921" ], "enzyme_list": [ "F1NML7-1" ], "evidence": [ { "id": "R-GGA-5693346", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5693346" } ] }, { "id": "R-GGA-6798751", "name": "Exocytosis of azurophil granule lumen proteins", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "extracellular region, azurophil granule lumen", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0X868-1", "A0A8V0XNR7-1", "A0A8V1AFG6-1", "A2JDL7-1", "F1NI04-1", "F1NML7-1", "F1NQI0-1", "A0A1D5PSE5-1", "P27043-1", "P30374-1", "A0A1D5PN36-1", "A0A1L1RSD2-1", "Q90629-1", "A0A8V0XXM5-1", "A0A8V0ZN26-1", "A0A8V1A4Q4-1", "A0A1D5PM49-1", "A0A8V0YHC8-1", "A0A8V0YL25-1", "A0A8V0YSD2-1", "E1BS94-1", "E1BSN7-1", "A0A8V0YVV2-1", "A0A8V0YW12-1", "A0A8V0Z0Z6-1", "A0A1D5PJC6-1", "A0A8V1AEN9-1", "F1NTQ2-1", "A0A1D5PXN4-1", "P00698-1", "A0A8V0Y6N9-1", "A0A8V0Y726-1", "A0A8V0ZQV0-1" ], "evidence": [ { "id": "R-GGA-6798751", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6798751" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-2022135", "participant_name": "NH3 [extracellular region]", "crossref": [ { "id": "16134", "database": "ChEBI", "url": "" }, { "id": "8145696", "database": "PubChem Substance", "url": "" }, { "id": "HMDB0000051", "database": "HMDB Metabolite", "url": "" }, { "id": "HMDB0033934", "database": "HMDB Metabolite", "url": "" }, { "id": "C00014", "database": "COMPOUND", "url": "" } ] }, { "participant_id": "R-ALL-83908", "participant_name": "Ade-Rib [extracellular region]", "crossref": [ { "id": "16335", "database": "ChEBI", "url": "" }, { "id": "C00212", "database": "COMPOUND", "url": "" }, { "id": "8143428", "database": "PubChem Substance", "url": "" }, { "id": "2844", "database": "Guide to Pharmacology - Ligands", "url": "" }, { "id": "ZINC000002169830", "database": "ZINC", "url": "" }, { "id": "HMDB0000050", "database": "HMDB Metabolite", "url": "" } ] }, { "participant_id": "R-ALL-83921", "participant_name": "Ino [extracellular region]", "crossref": [ { "id": "4554", "database": "Guide to Pharmacology - Ligands", "url": "" }, { "id": "C00294", "database": "COMPOUND", "url": "" }, { "id": "HMDB0000195", "database": "HMDB Metabolite", "url": "" }, { "id": "8144594", "database": "PubChem Substance", "url": "" }, { "id": "17596", "database": "ChEBI", "url": "" }, { "id": "ZINC000008855117", "database": "ZINC", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A0A1D5PJC6", "gene_name": "CPPED1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A1D5PJC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PJC6" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A1D5PJC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PJC6" } ] } ] }, { "uniprot_ac": "A0A1D5PM49", "gene_name": "GALNS", "activity": [ { "ec_number": "3.1.6.4", "activity": "Hydrolysis of the 6-sulfate groups of the N-acetyl-D-galactosamine 6-sulfate units of chondroitin sulfate and of the D-galactose 6-sulfate units of keratan sulfate.", "evidence": [ { "id": "A0A1D5PM49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PM49" } ] }, { "ec_number": "3.1.6.4", "activity": "", "evidence": [ { "id": "A0A1D5PM49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PM49" } ] } ] }, { "uniprot_ac": "A0A1D5PN36", "gene_name": "LOC107054567", "activity": [ { "ec_number": "3.4.21.4", "activity": "Preferential cleavage: Arg-|-Xaa, Lys-|-Xaa.", "evidence": [ { "id": "A0A1D5PN36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PN36" } ] }, { "ec_number": "3.4.21.4", "activity": "", "evidence": [ { "id": "A0A1D5PN36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PN36" } ] } ] }, { "uniprot_ac": "A0A1D5PSE5", "gene_name": "ACLY", "activity": [ { "ec_number": "2.3.3.8", "activity": "oxaloacetate + acetyl-CoA + ADP + phosphate = citrate + ATP + CoA.", "evidence": [ { "id": "A0A1D5PSE5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PSE5" } ] }, { "ec_number": "2.3.3.8", "activity": "", "evidence": [ { "id": "A0A1D5PSE5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PSE5" } ] } ] }, { "uniprot_ac": "A0A1D5PXN4", "gene_name": "PRKCD", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PXN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PXN4" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A1D5PXN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PXN4" } ] } ] }, { "uniprot_ac": "A0A1L1RSD2", "gene_name": "GUSB", "activity": [ { "ec_number": "3.2.1.31", "activity": "a beta-D-glucuronoside + H2O = D-glucuronate + an alcohol.", "evidence": [ { "id": "A0A1L1RSD2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RSD2" } ] }, { "ec_number": "3.2.1.31", "activity": "", "evidence": [ { "id": "A0A1L1RSD2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RSD2" } ] } ] }, { "uniprot_ac": "A0A3Q2UAL7", "gene_name": "LACC1", "activity": [ { "ec_number": "3.5.4.4", "activity": "2'-deoxyadenosine + H2O + H(+) = 2'-deoxyinosine + NH4(+).", "evidence": [ { "id": "A0A3Q2UAL7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UAL7" } ] }, { "ec_number": "2.4.2.1", "activity": "adenosine + phosphate = alpha-D-ribose 1-phosphate + adenine.", "evidence": [ { "id": "A0A3Q2UAL7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UAL7" } ] }, { "ec_number": "2.4.2.28", "activity": "S-methyl-5'-thioadenosine + phosphate = 5-(methylsulfanyl)-alpha-D-ribose 1-phosphate + adenine.", "evidence": [ { "id": "A0A3Q2UAL7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UAL7" } ] }, { "ec_number": "2.4.2.1", "activity": "", "evidence": [ { "id": "A0A3Q2UAL7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UAL7" } ] }, { "ec_number": "2.4.2.28", "activity": "", "evidence": [ { "id": "A0A3Q2UAL7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UAL7" } ] }, { "ec_number": "3.5.4.4", "activity": "", "evidence": [ { "id": "A0A3Q2UAL7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UAL7" } ] } ] }, { "uniprot_ac": "A0A8V0X868", "gene_name": "GGH", "activity": [ { "ec_number": "3.4.19.9", "activity": "(6S)-5,6,7,8-tetrahydrofolyl-(gamma-L-Glu)(n) + (n-1) H2O = (6S)-5,6,7,8-tetrahydrofolate + (n-1) L-glutamate.", "evidence": [ { "id": "A0A8V0X868", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X868" } ] }, { "ec_number": "3.4.19.9", "activity": "", "evidence": [ { "id": "A0A8V0X868", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X868" } ] } ] }, { "uniprot_ac": "A0A8V0XNR7", "gene_name": "CTSC", "activity": [ { "ec_number": "3.4.14.1", "activity": "Release of an N-terminal dipeptide, Xaa-Yaa-|-Zaa-, except when Xaa is Arg or Lys, or Yaa or Zaa is Pro.", "evidence": [ { "id": "A0A8V0XNR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNR7" } ] }, { "ec_number": "3.4.14.1", "activity": "", "evidence": [ { "id": "A0A8V0XNR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNR7" } ] } ] }, { "uniprot_ac": "A0A8V0XXM5", "gene_name": "ARSA", "activity": [ { "ec_number": "3.1.6.8", "activity": "an N-acyl-1-beta-D-(3-O-sulfo)-galactosyl-sphing-4-enine + H2O = a beta-D-galactosyl-(1<->1')-N-acylsphing-4-enine + sulfate + H(+).", "evidence": [ { "id": "A0A8V0XXM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XXM5" } ] }, { "ec_number": "3.1.6.8", "activity": "", "evidence": [ { "id": "A0A8V0XXM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XXM5" } ] } ] }, { "uniprot_ac": "A0A8V0Y6N9", "gene_name": "NAPRT", "activity": [ { "ec_number": "6.3.4.21", "activity": "5-phospho-alpha-D-ribose 1-diphosphate + nicotinate + ATP + H2O = nicotinate beta-D-ribonucleotide + ADP + phosphate + diphosphate.", "evidence": [ { "id": "A0A8V0Y6N9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y6N9" } ] }, { "ec_number": "6.3.4.21", "activity": "", "evidence": [ { "id": "A0A8V0Y6N9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y6N9" } ] } ] }, { "uniprot_ac": "A0A8V0Y726", "gene_name": "TXNDC5", "activity": [ { "ec_number": "5.3.4.1", "activity": "Catalyzes the rearrangement of -S-S- bonds in proteins.", "evidence": [ { "id": "A0A8V0Y726", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y726" } ] }, { "ec_number": "5.3.4.1", "activity": "", "evidence": [ { "id": "A0A8V0Y726", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y726" } ] } ] }, { "uniprot_ac": "A0A8V0YHC8", "gene_name": "VCP", "activity": [ { "ec_number": "3.6.4.6", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YHC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHC8" } ] }, { "ec_number": "3.6.4.6", "activity": "", "evidence": [ { "id": "A0A8V0YHC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHC8" } ] } ] }, { "uniprot_ac": "A0A8V0YL25", "gene_name": "PRDX6", "activity": [ { "ec_number": "1.11.1.27", "activity": "a hydroperoxide + 2 glutathione = an alcohol + glutathione disulfide + H2O.", "evidence": [ { "id": "A0A8V0YL25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL25" } ] }, { "ec_number": "1.11.1.27", "activity": "", "evidence": [ { "id": "A0A8V0YL25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL25" } ] } ] }, { "uniprot_ac": "A0A8V0YSD2", "gene_name": "FUCA1", "activity": [ { "ec_number": "3.2.1.51", "activity": "an alpha-L-fucoside + H2O = L-fucose + an alcohol.", "evidence": [ { "id": "A0A8V0YSD2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSD2" } ] }, { "ec_number": "3.2.1.51", "activity": "", "evidence": [ { "id": "A0A8V0YSD2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSD2" } ] } ] }, { "uniprot_ac": "A0A8V0YVV2", "gene_name": "GLA", "activity": [ { "ec_number": "3.2.1.-", "activity": "", "evidence": [ { "id": "A0A8V0YVV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YVV2" } ] } ] }, { "uniprot_ac": "A0A8V0YW12", "gene_name": "FRK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YW12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YW12" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0YW12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YW12" } ] } ] }, { "uniprot_ac": "A0A8V0Z0Z6", "gene_name": "GLB1", "activity": [ { "ec_number": "3.2.1.23", "activity": "Hydrolysis of terminal non-reducing beta-D-galactose residues in beta-D-galactosides.", "evidence": [ { "id": "A0A8V0Z0Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z0Z6" } ] }, { "ec_number": "3.2.1.23", "activity": "", "evidence": [ { "id": "A0A8V0Z0Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z0Z6" } ] } ] }, { "uniprot_ac": "A0A8V0ZN26", "gene_name": "LOC121106429", "activity": [ { "ec_number": "3.4.21.4", "activity": "Preferential cleavage: Arg-|-Xaa, Lys-|-Xaa.", "evidence": [ { "id": "A0A8V0ZN26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN26" } ] }, { "ec_number": "3.4.21.4", "activity": "", "evidence": [ { "id": "A0A8V0ZN26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN26" } ] } ] }, { "uniprot_ac": "A0A8V0ZQV0", "gene_name": "VAT1", "activity": [ { "ec_number": "1.6.5.5", "activity": "2 1,2-naphthoquinone + NADPH + H(+) = 2 1,2-naphthosemiquinone + NADP(+).", "evidence": [ { "id": "A0A8V0ZQV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQV0" } ] }, { "ec_number": "1.6.5.5", "activity": "", "evidence": [ { "id": "A0A8V0ZQV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQV0" } ] } ] }, { "uniprot_ac": "A0A8V0ZWX9", "gene_name": "ADA", "activity": [ { "ec_number": "3.5.4.4", "activity": "2'-deoxyadenosine + H2O + H(+) = 2'-deoxyinosine + NH4(+).", "evidence": [ { "id": "A0A8V0ZWX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWX9" } ] }, { "ec_number": "3.5.4.4", "activity": "", "evidence": [ { "id": "A0A8V0ZWX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWX9" } ] } ] }, { "uniprot_ac": "A0A8V1A4Q4", "gene_name": "MAPK3", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4Q4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4Q4" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V1A4Q4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4Q4" } ] } ] }, { "uniprot_ac": "A0A8V1AEN9", "gene_name": "DPP7", "activity": [ { "ec_number": "3.4.14.2", "activity": "Release of an N-terminal dipeptide, Xaa-Yaa-|-, preferentially when Yaa is Ala or Pro. Substrates are oligopeptides, preferentially tripeptides.", "evidence": [ { "id": "A0A8V1AEN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEN9" } ] }, { "ec_number": "3.4.14.2", "activity": "", "evidence": [ { "id": "A0A8V1AEN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEN9" } ] } ] }, { "uniprot_ac": "A0A8V1AFG6", "gene_name": "PTGES2", "activity": [ { "ec_number": "5.3.99.3", "activity": "prostaglandin H2 = prostaglandin E2.", "evidence": [ { "id": "A0A8V1AFG6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFG6" } ] }, { "ec_number": "5.3.99.3", "activity": "", "evidence": [ { "id": "A0A8V1AFG6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFG6" } ] } ] }, { "uniprot_ac": "A2JDL7", "gene_name": "LOC121107389", "activity": [ { "ec_number": "3.4.21.4", "activity": "Preferential cleavage: Arg-|-Xaa, Lys-|-Xaa.", "evidence": [ { "id": "A2JDL7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2JDL7" } ] }, { "ec_number": "3.4.21.4", "activity": "", "evidence": [ { "id": "A2JDL7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2JDL7" } ] } ] }, { "uniprot_ac": "E1BS94", "gene_name": "FUCA2", "activity": [ { "ec_number": "3.2.1.51", "activity": "an alpha-L-fucoside + H2O = L-fucose + an alcohol.", "evidence": [ { "id": "E1BS94", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BS94" } ] }, { "ec_number": "3.2.1.51", "activity": "", "evidence": [ { "id": "E1BS94", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BS94" } ] } ] }, { "uniprot_ac": "E1BSN7", "gene_name": "PYGB", "activity": [ { "ec_number": "2.4.1.1", "activity": "[(1->4)-alpha-D-glucosyl](n) + phosphate = [(1->4)-alpha-D-glucosyl](n-1) + alpha-D-glucose 1-phosphate.", "evidence": [ { "id": "E1BSN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BSN7" } ] }, { "ec_number": "2.4.1.1", "activity": "", "evidence": [ { "id": "E1BSN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BSN7" } ] } ] }, { "uniprot_ac": "F1NI04", "gene_name": "GNS", "activity": [ { "ec_number": "3.1.6.14", "activity": "Hydrolysis of the 6-sulfate groups of the N-acetyl-D-glucosamine 6-sulfate units of heparan sulfate and keratan sulfate.", "evidence": [ { "id": "F1NI04", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NI04" } ] }, { "ec_number": "3.1.6.14", "activity": "", "evidence": [ { "id": "F1NI04", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NI04" } ] } ] }, { "uniprot_ac": "F1NML7", "gene_name": "CECR1", "activity": [ { "ec_number": "3.5.4.4", "activity": "2'-deoxyadenosine + H2O + H(+) = 2'-deoxyinosine + NH4(+).", "evidence": [ { "id": "F1NML7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NML7" } ] }, { "ec_number": "3.5.4.4", "activity": "", "evidence": [ { "id": "F1NML7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NML7" } ] } ] }, { "uniprot_ac": "F1NQI0", "gene_name": "AGA", "activity": [ { "ec_number": "3.5.1.26", "activity": "N(4)-(beta-N-acetyl-D-glucosaminyl)-L-asparagine + H2O = N-acetyl-beta-D-glucosaminylamine + L-aspartate + H(+).", "evidence": [ { "id": "F1NQI0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NQI0" } ] }, { "ec_number": "3.5.1.26", "activity": "", "evidence": [ { "id": "F1NQI0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NQI0" } ] } ] }, { "uniprot_ac": "F1NTQ2", "gene_name": "HEXB", "activity": [ { "ec_number": "3.2.1.52", "activity": "Hydrolysis of terminal non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides.", "evidence": [ { "id": "F1NTQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NTQ2" } ] }, { "ec_number": "3.2.1.52", "activity": "", "evidence": [ { "id": "F1NTQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NTQ2" } ] } ] }, { "uniprot_ac": "P00698", "gene_name": "LYZ", "activity": [ { "ec_number": "3.2.1.17", "activity": "Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins.", "evidence": [ { "id": "P00698", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00698" } ] }, { "ec_number": "3.2.1.17", "activity": "", "evidence": [ { "id": "P00698", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00698" } ] } ] }, { "uniprot_ac": "P27043", "gene_name": "ANG", "activity": [ { "ec_number": "3.1.27.-", "activity": "", "evidence": [ { "id": "P27043", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P27043" } ] } ] }, { "uniprot_ac": "P30374", "gene_name": "", "activity": [ { "ec_number": "3.1.27.-", "activity": "", "evidence": [ { "id": "P30374", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P30374" } ] } ] }, { "uniprot_ac": "P84520", "gene_name": "ADA2", "activity": [ { "ec_number": "3.5.4.4", "activity": "2'-deoxyadenosine + H2O + H(+) = 2'-deoxyinosine + NH4(+).", "evidence": [ { "id": "P84520", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P84520" } ] }, { "ec_number": "3.5.4.4", "activity": "", "evidence": [ { "id": "P84520", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P84520" } ] } ] }, { "uniprot_ac": "Q5ZKP6", "gene_name": "ADA", "activity": [ { "ec_number": "3.5.4.4", "activity": "2'-deoxyadenosine + H2O + H(+) = 2'-deoxyinosine + NH4(+).", "evidence": [ { "id": "Q5ZKP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKP6" } ] }, { "ec_number": "3.5.4.4", "activity": "", "evidence": [ { "id": "Q5ZKP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKP6" } ] } ] }, { "uniprot_ac": "Q90629", "gene_name": "", "activity": [ { "ec_number": "3.4.21.4", "activity": "Preferential cleavage: Arg-|-Xaa, Lys-|-Xaa.", "evidence": [ { "id": "Q90629", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q90629" } ] }, { "ec_number": "3.4.21.4", "activity": "", "evidence": [ { "id": "Q90629", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q90629" } ] } ] } ], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1NML7-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 519, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1NML7-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1NML7" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1NML7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NML7" }, { "id": "PF00962", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00962" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Adenosine deaminase", "eco_id": "ECO_0000259", "start_pos": 207, "end_pos": 497, "start_aa": "Trp", "end_aa": "Arg", "glycosite_overlap": "" }, { "evidence": [ { "id": "F1NML7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NML7" }, { "id": "PF08451", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08451" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Adenosine/AMP deaminase N-terminal", "eco_id": "ECO_0000259", "start_pos": 33, "end_pos": 103, "start_aa": "Glu", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "3.5.4.4", "ec_name": "2'-deoxyadenosine + H2O + H(+) = 2'-deoxyinosine + NH4(+).", "evidence": [ { "id": "3.5.4.4", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:3.5.4.4" }, { "id": "3.5.4.4", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=3.5.4.4" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 128, "end_pos": 130 }, { "start_pos": 177, "end_pos": 179 }, { "start_pos": 188, "end_pos": 190 }, { "start_pos": 264, "end_pos": 266 }, { "start_pos": 300, "end_pos": 302 }, { "start_pos": 381, "end_pos": 383 }, { "start_pos": 399, "end_pos": 401 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1NMN0-1", "uniprot_ac": "F1NMN0", "uniprot_id": "F1NMN0_CHICK", "mass": { "chemical_mass": 88696.0, "monoisotopic_mass": 88696.0 }, "refseq": { "ac": "NP_001026379", "name": "cleavage and polyadenylation specificity factor subunit 2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026379" }, "gene_names": [ { "name": "CPSF2", "type": "recommended", "evidence": [ { "id": "F1NMN0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NMN0" } ] }, { "name": "CPSF2", "type": "synonym", "evidence": [ { "id": "NP_001026379", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026379" } ] } ], "protein_names": [ { "name": "Cleavage and polyadenylation specificity factor subunit 2", "type": "recommended", "evidence": [ { "id": "F1NMN0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NMN0/entry#names_and_taxonomy" } ] }, { "name": "Cleavage and polyadenylation specificity factor 100 kDa subunit", "type": "synonym", "evidence": [ { "id": "F1NMN0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NMN0/entry#names_and_taxonomy" } ] }, { "name": "cleavage and polyadenylation specific factor 2, 100kDa", "type": "synonym", "evidence": [ { "id": "NP_001026379", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026379" } ] }, { "name": "cleavage and polyadenylation specificity factor subunit 2", "type": "synonym", "evidence": [ { "id": "NP_001026379", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026379" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ851661.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000215.1. On Sep 23, 2021 this sequence version replaced NP_001026379.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001026379", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026379" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NMN0", "url": "https://www.uniprot.org/uniprotkb/F1NMN0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CPSF2", "url": "https://www.uniprot.org/uniprotkb/F1NMN0", "locus": { "chromosome": "5", "start_pos": 44110986, "end_pos": 44096827, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010015348", "url": "https://www.ensembl.org/id/ENSGALG00010015348" } ] } } ], "crossref": [ { "id": "F1NMN0", "url": "https://alphafold.ebi.ac.uk/entry/F1NMN0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000010783", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000010783", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd16293", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16293", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "423416", "url": "https://www.ncbi.nlm.nih.gov/gene/423416", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001279", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001279", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011108", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011108", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR022712", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022712", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR025069", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025069", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027075", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027075", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035639", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035639", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036866", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036866", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:423416", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423416", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QSRHNME", "url": "https://omabrowser.org/oma/group/QSRHNME/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YRZ9", "url": "https://www.orthodb.org/?gene=A0A8V0YRZ9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NMN0", "url": "https://www.orthodb.org/?gene=F1NMN0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45922", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45922", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45922:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45922:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07521", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07521", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF10996", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10996", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13299", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13299", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16661", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16661", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-77595", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-77595", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9770562", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9770562", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001026379", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026379", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YRZ9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRZ9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YRZ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRZ9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NMN0", "url": "https://www.uniprot.org/uniprotkb/F1NMN0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NMN0-1", "url": "https://www.uniprot.org/uniprotkb/F1NMN0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTSIIKLTTLSGVQEESALCYLLQVDEFRFLLDCGWDENFSMDIIDSLKKHVHQVDAVLLSHPDPLHLGALPYAVGKMGLNCAIYATIPVYKMGQMFMYDLYQSRHNTEDFTLFTLDDVDAAFDKIQQLKFSQIVNLKGKGHGLSITPLPAGHMIGGTIWKIVKDGEEEIVYAVDFNHKREIHLNGCSLEMLSRPSLLITDSFNATYVQPRRKQRDEQLLTNVLETLRGDGNVLIAVDTAGRVLELAQLLDQIWRTKDAGLGVYSLALLNNVSYNVVEFSKSQVEWMSDKLMRCFEDKRNNPFQFRHLSLCHSLSDLARVPSPKVVLASQPDLECGFSRDLFIQWCQDSKNSIILTYRTTPGTLARFLIDNPSEKVIDIELRRRVKLEGKELEEYLEKEKLKKEAAKKLEQSKEADIDSSDESDAEEDIDQPTVHKTKHDLMMKGEGSRKGSFFKQAKKSYPMFPAPEERIKWDEYGEIIKPEDFLVPELQATEEEKSKLESGLTNGEEPMDQDLSDVPTKCISATESMEIKARVTYIDYEGRSDGDSIKKIINQMKPRQLVIVHGPPEASQDLAECCRAFGGKDIKVYMPKLHETVDATSETHIYQVRLKDSLVSSLQFCKAKDAELAWIDGVLDMRVSKVDTGVILEEGELREDEELEMQVDMPSSDSSVIAQQKAMKSLFGDDDKEMCEESEIIPTLEPLPPHEVPGHQSVFMNEPRLSDFKQVLLREGIQAEFVGGVLVCNNMVAVRRTETGRIGLEGCLCQDFYRIRELLYKQYAIV", "length": 782, "header": "tr|F1NMN0-1|F1NMN0_CHICK Isoform 1 of Cleavage and polyadenylation specificity factor subunit 2 OS=Gallus gallus OX=9031 GN=CPSF2 PE=1 SV=1 CANONICAL=F1NMN0-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YRZ9-1", "url": "https://www.uniprot.org/uniprotkb/F1NMN0/entry#A0A8V0YRZ9-1", "sequence": { "sequence": "MFRVKGVILLKHVHQVDAVLLSHPDPLHLGALPYAVGKMGLNCAIYATIPVYKMGQMFMYDLYQSRHNTEDFTLFTLDDVDAAFDKIQQLKFSQIVNLKGKGHGLSITPLPAGHMIGGTIWKIVKDGEEEIVYAVDFNHKREIHLNGCSLEMLSRPSLLITDSFNATYVQPRRKQRDEQLLTNVLETLRGDGNVLIAVDTAGRVLELAQLLDQIWRTKDAGLGVYSLALLNNVSYNVVEFSKSQVEWMSDKLMRCFEDKRNNPFQFRHLSLCHSLSDLARVPSPKVVLASQPDLECGFSRDLFIQWCQDSKNSIILTYRTTPGTLARFLIDNPSEKVIDIELRRRVKLEGKELEEYLEKEKLKKEAAKKLEQSKEADIDSSDESDAEEDIDQPTVHKTKHDLMMKGEGSRKGSFFKQAKKSYPMFPAPEERIKWDEYGEIIKPEDFLVPELQATEEEKSKLESGLTNGEEPMDQDLSDVPTKCISATESMEIKARVTYIDYEGRSDGDSIKKIINQMKPRQLVIVHGPPEASQDLAECCRAFGGKDIKVYMPKLHETVDATSETHIYQVRLKDSLVSSLQFCKAKDAELAWIDGVLDMRVSKVDTGVILEEGELREDEELEMQVDMPSSDSSVIAQQKAMKSLFGDDDKEMCEESEIIPTLEPLPPHEVPGHQSVFMNEPRLSDFKQVLLREGIQAEFVGGVLVCNNMVAVRRTETGRIGLEGCLCQDFYRIRELLYKQYAIV", "length": 743, "header": "tr|A0A8V0YRZ9-1|A0A8V0YRZ9_CHICK Computationally mapped isoform of Cleavage and polyadenylation specificity factor subunit 2 OS=Gallus gallus OX=9031 GN=CPSF2 PE=1 SV=1 CANONICAL=F1NMN0-1" }, "locus": { "chromosome": "5", "start_pos": 44109289, "end_pos": 44098031, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010036894.1", "url": "https://www.ensembl.org/id/ENSGALT00010036894.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021485.1", "url": "https://www.ensembl.org/id/ENSGALP00010021485.1" } ] } }, { "isoform_ac": "F1NMN0-1", "url": "https://www.uniprot.org/uniprotkb/F1NMN0/entry#F1NMN0-1", "sequence": { "sequence": "MTSIIKLTTLSGVQEESALCYLLQVDEFRFLLDCGWDENFSMDIIDSLKKHVHQVDAVLLSHPDPLHLGALPYAVGKMGLNCAIYATIPVYKMGQMFMYDLYQSRHNTEDFTLFTLDDVDAAFDKIQQLKFSQIVNLKGKGHGLSITPLPAGHMIGGTIWKIVKDGEEEIVYAVDFNHKREIHLNGCSLEMLSRPSLLITDSFNATYVQPRRKQRDEQLLTNVLETLRGDGNVLIAVDTAGRVLELAQLLDQIWRTKDAGLGVYSLALLNNVSYNVVEFSKSQVEWMSDKLMRCFEDKRNNPFQFRHLSLCHSLSDLARVPSPKVVLASQPDLECGFSRDLFIQWCQDSKNSIILTYRTTPGTLARFLIDNPSEKVIDIELRRRVKLEGKELEEYLEKEKLKKEAAKKLEQSKEADIDSSDESDAEEDIDQPTVHKTKHDLMMKGEGSRKGSFFKQAKKSYPMFPAPEERIKWDEYGEIIKPEDFLVPELQATEEEKSKLESGLTNGEEPMDQDLSDVPTKCISATESMEIKARVTYIDYEGRSDGDSIKKIINQMKPRQLVIVHGPPEASQDLAECCRAFGGKDIKVYMPKLHETVDATSETHIYQVRLKDSLVSSLQFCKAKDAELAWIDGVLDMRVSKVDTGVILEEGELREDEELEMQVDMPSSDSSVIAQQKAMKSLFGDDDKEMCEESEIIPTLEPLPPHEVPGHQSVFMNEPRLSDFKQVLLREGIQAEFVGGVLVCNNMVAVRRTETGRIGLEGCLCQDFYRIRELLYKQYAIV", "length": 782, "header": "tr|F1NMN0-1|F1NMN0_CHICK Isoform 1 of Cleavage and polyadenylation specificity factor subunit 2 OS=Gallus gallus OX=9031 GN=CPSF2 PE=1 SV=1 CANONICAL=F1NMN0-1" }, "locus": { "chromosome": "5", "start_pos": 44109289, "end_pos": 44097755, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010036899.1", "url": "https://www.ensembl.org/id/ENSGALT00010036899.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021487.1", "url": "https://www.ensembl.org/id/ENSGALP00010021487.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:423416", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423416", "resource": "KEGG Pathway" }, { "id": "R-GGA-77595", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-77595", "resource": "Reactome", "description": "Processing of Intronless Pre-mRNAs" }, { "id": "R-GGA-9770562", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9770562", "resource": "Reactome", "description": "mRNA Polyadenylation" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A9J7JTB4-1", "protein_name": "Cleavage and polyadenylation specificity factor subunit 2", "gene_name": "Cpsf2", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MVPGEPDQADNHYWTRKMTSIIKLTTLSGVQEESALCYLLQVDEFRFLLDCGWDEHFSMDIIDSLRKHVHQIDAVLLSHPDPLHLGALPFAVGKLGLNCAIYATIPVYKMGQMFMYDLYQSRHNTEDFTLFTLDDVDAAFDKIQQLKFSQIVNLKGKGHGLSITPLPAGHMIGGTIWKIVKDGEEEIVYAVDFNHKREIHLNGCSLEMLSRPSLLITDSFNATYVQPRRKQRDEQLLTNVLETLRGDGNVLIAVDTAGRVLELAQLLDQIWRTKDAGLGVYSLALLNNVSYNVVEFSKSQVEWMSDKLMRCFEDKRNNPFQFRHLSLCHGLSDLARVPSPKVVLASQPDLECGFSRDLFIQWCQDPKNSIILTYRTTPGTLARFLIDNPSEKVTEIELRKRVKLEGKELEEYVEKEKLKKEAAKKLEQSKEADIDSSDESDVEEDIDQPSAHKTKHDLMMKGEGSRKGSFFKQAKKSYPMFPAPEERIKWDEYGEIIKPEDFLVPELQATEEEKNKLESGLTNGDEPMDQDLSDVPTKCVSATESIEIKARVTYIDYEGRSDGDSIKKIINQMKPRQLIIVHGPPEASQDLAECCRAFGGKDIKVYMPKLHETVDATSETHIYQVRLKDSLVSSLQFCKAKDAELAWIDGVLDMRVSKVDTGVILEEGELKDDGEDSEMQVDGPSDSSAIAQQKAMKSLFGDDDKELGEESEIIPTLEPLPPHEVPGHQSVFMNEPRLSDFKQVLLREGIQAEFVGGVLVCNNQVAVRRTETGRIGLEGCLCQDFYRIRDLLYEQYAIV", "length": 799 }, "evidence": [ { "id": "F1NMN0", "url": "https://omabrowser.org/oma/group/F1NMN0/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0ABK0M5H2-1", "protein_name": "Cleavage and polyadenylation specificity factor subunit 2", "gene_name": "Cpsf2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTSIIKLTTLSGVQEESALCYLLQVDEFRFLLDCGWDEHFSVDIIDSLRKHVHQIDAVLLSHPDPLHLGALPFAVGKLGLNCAIYATIPVYKMGQMFMYDLYQSRHNTEDFTLFTLDDVDAAFDKIQQLKFSQIVNLKGKGHGLSITPLPAGHMIGGTIWKIVKDGEEEIVYAVDFNHKREIHLNGCSLEMLSRPSLLITDSFNATYVQPRRKQRDEQLLTNVLETLRGDGNVLIAVDTAGRVLELAQLLDQIWRTKDAGLGVYSLALLNNVSYNVVEFSKSQVEWMSDKLMRCFEDKRNNPFQFRHLSLCHGLSDLARVPSPKVVLASQPDLECGFSRDLFIQWCQDPKNSIILTYRTTPGTLARFLIDNPSEKVTEIELRKRVKLEGKELEEYVEKEKLKKEAAKKLEQSKEADIDSSDESDVEEDVDQPTAHKTKHDLMMKGEGSRKGSFFKQAKKSYPMFPAPEERIKWDEYGEIIKDSLFRPEDFLVPELQATEEEKSKLESGLTNGEEPMDQDLSDVPTKCVSATESIEIKARVTYIDYEGRSDGDSIKKIINQMKPRQLIIVHGPPEASQDLAECCRAFGGKDIKVYMPKLHETVDATSETHIYQVRLKDSLVSSLQFCKAKDAELAWIDGVLDMRVSKVDTGVILEEGELKDDGEDSEMQVDAPSDSSVIAQQKAMKSLFGDDEKELGEESEVIPTLEPLPPHEVPGHQSVFMNEPRLSDFKQVLLREGIQAEFVGGVLVCNNQVAVRRTETGRIGLEGCLCQDFYRIRDLLYEQYAIV", "length": 787 }, "evidence": [ { "id": "F1NMN0", "url": "https://omabrowser.org/oma/group/F1NMN0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1QVV4-1", "protein_name": "Cleavage and polyadenylation specificity factor subunit 2", "gene_name": "cpsf2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTSIIKLTALSGVQEESALCYLLQVDEFRFLLDCGWDETFSMDIIDSLKRYVHQVDAVLLSHPDHVHLGALPYAVGKLGLNCTIYATIPVYKMGQMFMYDLYQSRHNTEDFTLFTLDDVDSAFDKIQQLKYSQIVNLKGKGHGLSITPLPAGHMIGGTIWKIVKDGEEEIIYGVDFNHKREIHLNGCSLESLSRPSLLITDSFNASYVQPRRKQRDEQLLTNVMETLRGDGNVLIAVDTAGRVLELAQLLDQIWRTKDAGLGVYSLALLNNVSYNVVEFSKSQVEWMSDKLMRCFEDKRNNPFQFRHLSLCHSLSDLARVPSPKVVLCSQPDLESGFSRELFIQWCQDAKNSVILTYRTTPGTLARYLIDNPGEKRIELEIRKRCRLEGRELEEYMEKERMKKEAAKKLEQAKEVDLDSSDESDMEDDLEQPAVVKTKHHDLMMKGEGGRKGGFFKQAKKSYPMFPTHEERIKWDEYGEIIRPEDFLVPELQATEEEKSKLESGLTNGEEPMEQDLSDVPTKCTSTTQTLDIRARVMYIDYEGRSDGDSIKKIINQMKPRQLIIVHGPPDASQDLAESCKAYSGKDIKVYIPKLQETVDATSETHIYQVRLKDSLVSSLQFCKARDTELAWIDGVLDMRVEKVDTGVIVELGEAKDEAEEGGEQGMEVTEELNTEPSTAAAANQRAMKTLFGEDEKEISEESDVIPTLEPLPAHEVPGHQSVFINEPRLSDFKQVLLREGIQAEFVGGVLVCNNLVAVRRTEAGRICLEGCHCDDYYRIRELLYEQYAVV", "length": 790 }, "evidence": [ { "id": "F1NMN0", "url": "https://omabrowser.org/oma/group/F1NMN0/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "O35218-1", "protein_name": "Cleavage and polyadenylation specificity factor subunit 2", "gene_name": "Cpsf2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTSIIKLTTLSGVQEESALCYLLQVDEFRFLLDCGWDEHFSVDIIDSLRKHVHQIDAVLLSHPDPLHLGALPFAVGKLGLNCAIYATIPVYKMGQMFMYDLYQSRHNTEDFTLFTLDDVDAAFDKIQQLKFSQIVNLKGKGHGLSITPLPAGHMIGGTIWKIVKDGEEEIVYAVDFNHKREIHLNGCSLEMLSRPSLLITDSFNATYVQPRRKQRDEQLLTNVLETLRGDGNVLIAVDTAGRVLELAQLLDQIWRTKDAGLGVYSLALLNNVSYNVVEFSKSQVEWMSDKLMRCFEDKRNNPFQFRHLSLCHGLSDLARVPSPKVVLASQPDLECGFSRDLFIQWCQDPKNSIILTYRTTPGTLARFLIDNPTEKVTEIELRKRVKLEGKELEEYVEKEKLKKEAAKKLEQSKEADIDSSDESDVEEDVDQPSAHKTKHDLMMKGEGSRKGSFFKQAKKSYPMFPAPEERIKWDEYGEIIKPEDFLVPELQATEEEKSKLESGLTNGEEPMDQDLSDVPTKCVSATESIEIKARVTYIDYEGRSDGDSIKKIINQMKPRQLIIVHGPPEASQDLAECCRAFGGKDIKVYMPKLHETVDATSETHIYQVRLKDSLVSSLQFCKAKDAELAWIDGVLDMRVSKVDTGVILEEGELKDDGEDSEMQVDAPSDSSAMAQQKAMKSLFGEDEKELGEETEIIPTLEPLPPHEVPGHQSVFMNEPRLSDFKQVLLREGIQAEFVGGVLVCNNQVAVRRTETGRIGLEGCLCQDFYRIRDLLYEQYAIV", "length": 782 }, "evidence": [ { "id": "F1NMN0", "url": "https://omabrowser.org/oma/group/F1NMN0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q10568-1", "protein_name": "Cleavage and polyadenylation specificity factor subunit 2", "gene_name": "CPSF2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MTSIIKLTTLSGVQEESALCYLLQVDEFRFLLDCGWDEHFSMDIIDSLRKHVHQIDAVLLSHPDPLHLGALPYAVGKLGLNCAIYATIPVYKMGQMFMYDLYQSRHNTEDFTLFTLDDVDAAFDKIQQLKFSQIVNLKGKGHGLSITPLPAGHMIGGTIWKIVKDGEEEIVYAVDFNHKREIHLNGCSLEMLSRPSLLITDSFNATYVQPRRKQRDEQLLTNVLETLRGDGNVLIAVDTAGRVLELAQLLDQIWRTKDAGLGVYSLALLNNVSYNVVEFSKSQVEWMSDKLMRCFEDKRNNPFQFRHLSLCHGLSDLARVPSPKVVLASQPDLECGFSRDLFIQWCQDPKNSIILTYRTTPGTLARFLIDNPSEKVTEIELRKRVKLEGKELEEYLEKEKLKKEAAKKLEQSKEADIDSSDESDAEEDIDQPSAHKTKHDLMMKGEGSRKGSFFKQAKKSYPMFPAPEERIKWDEYGEIIKPEDFLVPELQATEEEKSKLESGLTNGDEPMDQDLSDVPTKCISTTESIEIKARVTYIDYEGRSDGDSIKKIINQMKPRQLIIVHGPPEASQDLAECCRAFGGKDIKVYMPKLHETVDATSETHIYQVRLKDSLVSSLQFCKAKDAELAWIDGVLDMRVSKVDTGVILEEGELKDDGEDSEMQVDAPSDSSVIAQQKAMKSLFGDDEKETGEESEIIPTLEPLPPHEVPGHQSVFMNEPRLSDFKQVLLREGIQAEFVGGVLVCNNQVAVRRTETGRIGLEGCLCQDFYRIRDLLYEQYAIV", "length": 782 }, "evidence": [ { "id": "F1NMN0", "url": "https://omabrowser.org/oma/group/F1NMN0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q12102-1", "protein_name": "Cleavage factor two protein 2", "gene_name": "CFT2", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MTYKYNCCDDGSGTTVGSVVRFDNVTLLIDPGWNPSKVSYEQCIKYWEKVIPEIDVIILSQPTIECLGAHSLLYYNFTSHFISRIQVYATLPVINLGRVSTIDSYASAGVIGPYDTNKLDLEDIEISFDHIVPLKYSQLVDLRSRYDGLTLLAYNAGVCPGGSIWCISTYSEKLVYAKRWNHTRDNILNAASILDATGKPLSTLMRPSAIITTLDRFGSSQPFKKRSKIFKDTLKKGLSSDGSVIIPVDMSGKFLDLFTQVHELLFESTKINAHTQVPVLILSYARGRTLTYAKSMLEWLSPSLLKTWENRNNTSPFEIGSRIKIIAPNELSKYPGSKICFVSEVGALINEVIIKVGNSEKTTLILTKPSFECASSLDKILEIVEQDERNWKTFPEDGKSFLCDNYISIDTIKEEPLSKEETEAFKVQLKEKKRDRNKKILLVKRESKKLANGNAIIDDTNGERAMRNQDILVENVNGVPPIDHIMGGDEDDDEEEENDNLLNLLKDNSEKSAAKKNTEVPVDIIIQPSAASKHKMFPFNPAKIKKDDYGTVVDFTMFLPDDSDNVNQNSRKRPLKDGAKTTSPVNEEDNKNEEEDGYNMSDPISKRSKHRASRYSGFSGTGEAENFDNLDYLKIDKTLSKRTISTVNVQLKCSVVILNLQSLVDQRSASIIWPSLKSRKIVLSAPKQIQNEEITAKLIKKNIEVVNMPLNKIVEFSTTIKTLDISIDSNLDNLLKWQRISDSYTVATVVGRLVKESLPQVNNHQKTASRSKLVLKPLHGSSRSHKTGALSIGDVRLAQLKKLLTEKNYIAEFKGEGTLVINEKVAVRKINDAETIIDGTPSELFDTVKKLVTDMLAKI", "length": 859 }, "evidence": [ { "id": "F1NMN0", "url": "https://omabrowser.org/oma/group/F1NMN0/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q55BS1-1", "protein_name": "Cleavage and polyadenylation specificity factor subunit 2", "gene_name": "cpsf2", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MASIIKFTALSGAKDESPPCYLLEIDDFCILLDCGLSYNLDFSLLEPLEKVAKKIDAVLLSHSDTTHIGGLPYVVGKYGLTGTIYGTTPVLKMGTMFLYDLYENKMSQEEFQQYSLDNIDSCFGEDRFKELSFSQHYSLSGKGKGISITPYLAGHTIGASVWKITKGTYSIVYAIDYNHRNEGHLDSLQLTSDILKPSLLITDSKGVDKTLAFKKTITRDQSLFEQINRNLRDGGNVLIPVDTAGRVLELLLCIENYWSKNKSLALYSVVFLGRFSFSVCQFARSQLEFMSSTASVKFEQNIENPFSFKHIKILSSLEELQELPDTNKVILTSSQDLETGFSRELFIQWCSDPKTLILFTQKIPKDSLADKLIKQYSTPNGRGKCIEIVQGSRVPLTGDELLQYEMEQAKQREEKRLEQLRKEQEEREERERLEEEEREQLLNATNQDQLQQLLQLQQQKERGIIDDSMVHMKNPFENDRFDLLDSEFKKQSMITMFPYFEKHLKWGEYGEEDDDLILRNQDKKVEEVTMEEDEIQEQEIPKKIITQTLRLPINCKIQTIDYEGCSDGRSIKAIIQQIAPTKLVLIRGSEQQSQSIENYVKENIRTKGIYIPSIGEQLDLTSDTNVYELLLKDSLVNTLKTSKILDYEVSYIQGKVDILDGSNVPVLDLIQSIPINNNNNNNNNNNNNNNNNNNNTTMMTTTTTTTNGHDESFIGDIKLSDLKQVLVNAGIQVQFDQGILNCGGLVYIWRDEDHGGNSIINVDGIISDEYYLIKELLYKQFQIV", "length": 784 }, "evidence": [ { "id": "F1NMN0", "url": "https://omabrowser.org/oma/group/F1NMN0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q9LKF9-1", "protein_name": "Cleavage and polyadenylation specificity factor subunit 2", "gene_name": "CPSF100", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MGTSVQVTPLCGVYNENPLSYLVSIDGFNFLIDCGWNDLFDTSLLEPLSRVASTIDAVLLSHPDTLHIGALPYAMKQLGLSAPVYATEPVHRLGLLTMYDQFLSRKQVSDFDLFTLDDIDSAFQNVIRLTYSQNYHLSGKGEGIVIAPHVAGHMLGGSIWRITKDGEDVIYAVDYNHRKERHLNGTVLQSFVRPAVLITDAYHALYTNQTARQQRDKEFLDTISKHLEVGGNVLLPVDTAGRVLELLLILEQHWSQRGFSFPIYFLTYVSSSTIDYVKSFLEWMSDSISKSFETSRDNAFLLRHVTLLINKTDLDNAPPGPKVVLASMASLEAGFAREIFVEWANDPRNLVLFTETGQFGTLARMLQSAPPPKFVKVTMSKRVPLAGEELIAYEEEQNRLKREEALRASLVKEEETKASHGSDDNSSEPMIIDTKTTHDVIGSHGPAYKDILIDGFVPPSSSVAPMFPYYDNTSEWDDFGEIINPDDYVIKDEDMDRGAMHNGGDVDGRLDEATASLMLDTRPSKVMSNELIVTVSCSLVKMDYEGRSDGRSIKSMIAHVSPLKLVLVHAIAEATEHLKQHCLNNICPHVYAPQIEETVDVTSDLCAYKVQLSEKLMSNVIFKKLGDSEVAWVDSEVGKTERDMRSLLPMPGAASPHKPVLVGDLKIADFKQFLSSKGVQVEFAGGGALRCGEYVTLRKVGPTGQKGGASGPQQILIEGPLCEDYYKIRDYLYSQFYLL", "length": 739 }, "evidence": [ { "id": "F1NMN0", "url": "https://omabrowser.org/oma/group/F1NMN0/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9P2I0-1", "protein_name": "Cleavage and polyadenylation specificity factor subunit 2", "gene_name": "CPSF2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTSIIKLTTLSGVQEESALCYLLQVDEFRFLLDCGWDEHFSMDIIDSLRKHVHQIDAVLLSHPDPLHLGALPYAVGKLGLNCAIYATIPVYKMGQMFMYDLYQSRHNTEDFTLFTLDDVDAAFDKIQQLKFSQIVNLKGKGHGLSITPLPAGHMIGGTIWKIVKDGEEEIVYAVDFNHKREIHLNGCSLEMLSRPSLLITDSFNATYVQPRRKQRDEQLLTNVLETLRGDGNVLIAVDTAGRVLELAQLLDQIWRTKDAGLGVYSLALLNNVSYNVVEFSKSQVEWMSDKLMRCFEDKRNNPFQFRHLSLCHGLSDLARVPSPKVVLASQPDLECGFSRDLFIQWCQDPKNSIILTYRTTPGTLARFLIDNPSEKITEIELRKRVKLEGKELEEYLEKEKLKKEAAKKLEQSKEADIDSSDESDIEEDIDQPSAHKTKHDLMMKGEGSRKGSFFKQAKKSYPMFPAPEERIKWDEYGEIIKPEDFLVPELQATEEEKSKLESGLTNGDEPMDQDLSDVPTKCISTTESIEIKARVTYIDYEGRSDGDSIKKIINQMKPRQLIIVHGPPEASQDLAECCRAFGGKDIKVYMPKLHETVDATSETHIYQVRLKDSLVSSLQFCKAKDAELAWIDGVLDMRVSKVDTGVILEEGELKDDGEDSEMQVEAPSDSSVIAQQKAMKSLFGDDEKETGEESEIIPTLEPLPPHEVPGHQSVFMNEPRLSDFKQVLLREGIQAEFVGGVLVCNNQVAVRRTETGRIGLEGCLCQDFYRIRDLLYEQYAIV", "length": 782 }, "evidence": [ { "id": "F1NMN0", "url": "https://omabrowser.org/oma/group/F1NMN0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9V3D6-1", "protein_name": "Probable cleavage and polyadenylation specificity factor subunit 2", "gene_name": "Cpsf100", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MTSIIKLHTISGAMDESPPCYILQIDDVRILLDCGWDEKFDANFIKELKRQVHTLDAVLLSHPDAYHLGALPYLVGKLGLNCPIYATIPVFKMGQMFMYDLYMSHFNMGDFDLFSLDDVDTAFEKITQLKYNQTVSLKDKGYGISITPLNAGHMIGGTIWKIVKVGEEDIVYATDFNHKKERHLSGCELDRLQRPSLLITDAYNAQYQQARRRARDEKLMTNILQTVRNNGNVLIAVDTAGRVLELAHMLDQLWKNKESGLMAYSLALLNNVSYNVIEFAKSQIEWMSDKLTKAFEGARNNPFQFKHIQLCHSLADVYKLPAGPKVVLASTPDLESGFTRDLFVQWASNANNSIILTTRTSPGTLAMELVENCAPGKQIELDVRRRVDLEGAELEEYLRTQGEKLNPLIVKPDVEEESSSESEDDIEMSVITGKHDIVVRPEGRHHSGFFKSNKRHHVMFPYHEEKVKCDEYGEIINLDDYRIADATGYEFVPMEEQNKENVKKEEPGIGAEQQANGGIVDNDVQLLEKPTKLISQRKTIEVNAQVQRIDFEGRSDGESMLKILSQLRPRRVIVIHGTAEGTQVVARHCEQNVGARVFTPQKGEIIDVTSEIHIYQVRLTEGLVSQLQFQKGKDAEVAWVDGRLGMRVKAIEAPMDVTVEQDASVQEGKTLTLETLADDEIPIHNSVLINELKLSDFKQTLMRNNINSEFSGGVLWCSNGTLALRRVDAGKVAMEGCLSEEYYKIRELLYEQYAIV", "length": 756 }, "evidence": [ { "id": "F1NMN0", "url": "https://omabrowser.org/oma/group/F1NMN0/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "glutamatergic synapse", "id": "GO:0098978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098978", "evidence": [ { "database": "UniProtKB", "id": "F1NMN0", "url": "https://www.uniprot.org/uniprotkb/F1NMN0" } ], "pmid": "" }, { "name": "postsynapse", "id": "GO:0098794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098794", "evidence": [ { "database": "UniProtKB", "id": "F1NMN0", "url": "https://www.uniprot.org/uniprotkb/F1NMN0" } ], "pmid": "" }, { "name": "mRNA cleavage and polyadenylation specificity factor complex", "id": "GO:0005847", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005847", "evidence": [ { "database": "UniProtKB", "id": "F1NMN0", "url": "https://www.uniprot.org/uniprotkb/F1NMN0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "F1NMN0", "url": "https://www.uniprot.org/uniprotkb/F1NMN0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "mRNA 3'-end processing by stem-loop binding and cleavage", "id": "GO:0006398", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006398", "evidence": [ { "database": "UniProtKB", "id": "F1NMN0", "url": "https://www.uniprot.org/uniprotkb/F1NMN0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 204, "end_pos": 206, "annotation": "n_glycosylation_sequon" }, { "start_pos": 271, "end_pos": 273, "annotation": "n_glycosylation_sequon" }, { "start_pos": 39, "end_pos": 41, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1NMN0-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 782, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1NMN0-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1NMN0" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 204, "end_pos": 206 }, { "start_pos": 271, "end_pos": 273 }, { "start_pos": 39, "end_pos": 41 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": 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"sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1NN48-1", "uniprot_ac": "F1NN48", "uniprot_id": "F1NN48_CHICK", "mass": { "chemical_mass": 15944.0, "monoisotopic_mass": 15944.0 }, "refseq": { "ac": "NP_001012318", "name": "baculoviral IAP repeat-containing protein 5 isoform 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012318" }, "gene_names": [ { "name": "BIRC5", "type": "recommended", "evidence": [ { "id": "F1NN48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NN48" } ] }, { "name": "BIRC5", "type": "synonym", "evidence": [ { "id": "NP_001012318", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012318" } ] }, { "name": "survivin", "type": "synonym", "evidence": [ { "id": "NP_001012318", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012318" } ] } ], "protein_names": [ { "name": "Baculoviral IAP repeat containing 5", "type": "synonym", "evidence": [ { "id": "F1NN48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NN48/entry#names_and_taxonomy" } ] }, { "name": "baculoviral IAP repeat-containing 5 (survivin)", "type": "synonym", "evidence": [ { "id": "NP_001012318", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012318" } ] }, { "name": "baculoviral IAP repeat-containing protein 5 isoform 1", "type": "synonym", "evidence": [ { "id": "NP_001012318", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012318" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: HAEK01121505.1, BU462955.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN06143078 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000062.1. Transcript Variant: This variant (1) encodes the longest isoform (1). Sequence Note: This RefSeq record was created from transcript sequence data from multiple strains because no single transcript from the same strain was available for the full length of the gene.", "evidence": [ { "database": "RefSeq", "id": "NP_001012318", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012318" } ] }, { "annotation": "High survivin expression is associated with lymph node micrometastasis in non-small cell lung cancer.", "evidence": [ { "database": "RefSeq", "id": "NP_001012318", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012318" }, { "database": "PubMed", "id": "23404657", "url": "https://glygen.org/publication/PubMed/23404657" } ] }, { "annotation": "Results showed that transfection of miR-34a mimic significantly suppressed cell proliferation with decreased survivin protein expression", "evidence": [ { "database": "RefSeq", "id": "NP_001012318", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012318" }, { "database": "PubMed", "id": "22246523", "url": "https://glygen.org/publication/PubMed/22246523" } ] }, { "annotation": "Survivin is a dual regulator of lens epithelial cell proliferation and lens fiber cell differentiation. Erratum:[Mol Vis. 2019 Aug 23;25:478. PMID: 32546935]", "evidence": [ { "database": "RefSeq", "id": "NP_001012318", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012318" }, { "database": "PubMed", "id": "23213276", "url": "https://glygen.org/publication/PubMed/23213276" } ] }, { "annotation": "The isolation of two conditional knockouts of the survivin gene in chicken DT40 cells, is described.", "evidence": [ { "database": "RefSeq", "id": "NP_001012318", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012318" }, { "database": "PubMed", "id": "18936249", "url": "https://glygen.org/publication/PubMed/18936249" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NN48", "url": "https://www.uniprot.org/uniprotkb/F1NN48" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "BIRC5", "url": 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"id": "IPR051190", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051190", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:374078", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:374078", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "RSHTKNC", "url": "https://omabrowser.org/oma/group/RSHTKNC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1NN48", "url": "https://www.orthodb.org/?gene=F1NN48", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46771", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46771", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46771:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46771:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00653", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00653", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-141430", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-141430", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-141444", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-141444", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-2467813", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2467813", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-2500257", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2500257", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-4615885", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-4615885", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-5663220", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5663220", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-8951664", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8951664", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9648025", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9648025", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001012318", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012318", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1NN48", "url": "https://www.uniprot.org/uniprotkb/F1NN48", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NN48-1", "url": "https://www.uniprot.org/uniprotkb/F1NN48-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAYAEMLPKEWLVYLVSTRAATFRNWPFTEGCACTPERMAAAGFVHCPSENSPDVVQCFFCLKELEGWEPDDDPLEEHKKHSAGCAFAALQKDPSNLTVQEFLKLDKKRTKNVIKKAISQKETDIEDVAKGVRHAIENMGP", "length": 142, "header": "tr|F1NN48-1|F1NN48_CHICK Isoform 1 of Baculoviral IAP repeat containing 5 OS=Gallus gallus OX=9031 GN=BIRC5 PE=3 SV=1 CANONICAL=F1NN48-1" }, "isoforms": [ { "isoform_ac": "F1NN48-1", "url": "https://www.uniprot.org/uniprotkb/F1NN48/entry#F1NN48-1", "sequence": { "sequence": "MAAYAEMLPKEWLVYLVSTRAATFRNWPFTEGCACTPERMAAAGFVHCPSENSPDVVQCFFCLKELEGWEPDDDPLEEHKKHSAGCAFAALQKDPSNLTVQEFLKLDKKRTKNVIKKAISQKETDIEDVAKGVRHAIENMGP", "length": 142, "header": "tr|F1NN48-1|F1NN48_CHICK Isoform 1 of Baculoviral IAP repeat containing 5 OS=Gallus gallus OX=9031 GN=BIRC5 PE=3 SV=1 CANONICAL=F1NN48-1" }, "locus": { "chromosome": "3", "start_pos": 15115727, "end_pos": 15115007, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010045135.1", "url": "https://www.ensembl.org/id/ENSGALT00010045135.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026959.1", "url": "https://www.ensembl.org/id/ENSGALP00010026959.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Deconstructing Survivin: comprehensive genetic analysis of Survivin function by conditional knockout in a vertebrate cell line.", "journal": "The Journal of cell biology", "date": "2008-10-20", "authors": "Yue Zuojun, Carvalho Ana, Xu Zhenjie, Yuan Xuemei, Cardinale Stefano, Ribeiro Susana, Lai Fan, Ogawa Hiromi, Gudmundsdottir Elisabet, Gassmann Reto, Morrison Ciaran G, Ruchaud Sandrine, Earnshaw William C", "evidence": [ { "database": "RefSeq", "id": "NP_001012318", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012318" } ], "reference": [ { "type": "PubMed", "id": "18936249", "url": "https://glygen.org/publication/PubMed/18936249" } ] }, { "title": "MicroRNA-34a affects the occurrence of laryngeal squamous cell carcinoma by targeting the antiapoptotic gene survivin.", "journal": "Medical oncology (Northwood, London, England)", "date": "2012-12", "authors": "Shen Zhisen, Zhan Guowen, Ye Dong, Ren Yuan, Cheng Lixin, Wu Zhenhua, Guo Junming", "evidence": [ { "database": "RefSeq", "id": "NP_001012318", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012318" } ], "reference": [ { "type": "PubMed", "id": "22246523", "url": "https://glygen.org/publication/PubMed/22246523" } ] }, { "title": "Survivin expression is associated with lens epithelial cell proliferation and fiber cell differentiation.", "journal": "Molecular vision", "date": "2012", "authors": "Jarrin Miguel, Mansergh Fiona C, Boulton Michael E, Gunhaga Lena, Wride Michael A", "evidence": [ { "database": "RefSeq", "id": "NP_001012318", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012318" } ], "reference": [ { "type": "PubMed", "id": "23213276", "url": "https://glygen.org/publication/PubMed/23213276" } ] }, { "title": "Gene diagnosis of micrometastases in regional lymph nodes of patients with stage I non-small cell lung cancer: impact on staging and prognosis.", "journal": "Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico", "date": "2013-11", "authors": "Li J, Li Z-N, Yu L-C, Shi S-B, Ge L-P, Wu J-R, Hu Y-M", "evidence": [ { "database": "RefSeq", "id": "NP_001012318", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012318" } ], "reference": [ { "type": "PubMed", "id": "23404657", "url": "https://glygen.org/publication/PubMed/23404657" } ] } ], "pathway": [ { "id": "gga:374078", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:374078", "resource": "KEGG Pathway" }, { "id": "R-GGA-141430", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-141430", "resource": "Reactome", "description": "Inactivation of APC/C via direct inhibition of the APC/C complex" }, { "id": "R-GGA-141444", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-141444", "resource": "Reactome", "description": "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" }, { "id": "R-GGA-2467813", "name": "", "url": 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preliminary review. The reference sequence was derived from CN226165.1, BX950659.1 and BU114881.1. On May 5, 2013 this sequence version replaced XP_417503.1. Sequence Note: This RefSeq record was created from transcript data from different strains because no single transcript from the same strain was available for the full length of the gene. The extent of this transcript is supported by transcript alignments and orthologous data.", "evidence": [ { "database": "RefSeq", "id": "NP_001264944", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264944" } ] }, { "annotation": "Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. 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"end_pos": 12679251, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010015141", "url": "https://www.ensembl.org/id/ENSGALG00010015141" } ] } } ], "crossref": [ { "id": "F1NP43", "url": "https://alphafold.ebi.ac.uk/entry/F1NP43", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000007792", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000007792", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd23165", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd23165", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "419337", "url": "https://www.ncbi.nlm.nih.gov/gene/419337", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002777", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002777", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009053", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009053", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016661", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016661", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:419337", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419337", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "NARMDEF", "url": "https://omabrowser.org/oma/group/NARMDEF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1NP43", "url": "https://www.orthodb.org/?gene=F1NP43", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21100", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21100", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21100:SF9", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21100:SF9", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01920", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01920", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001264944", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264944", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1NP43", "url": "https://www.uniprot.org/uniprotkb/F1NP43", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NP43-1", "url": "https://www.uniprot.org/uniprotkb/F1NP43-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAATMKKAAAEDVNVTFEDQQKINKFARNTSRITELKEEIEVKKKQLQNLEDACDDIMMLDDDSLLIPYQIGDVFISHSQEETQEMLEEAKKSLQEEIETLESRVESIQRVLSDLKVQLYAKFGNNINLEAEDS", "length": 134, "header": "tr|F1NP43-1|F1NP43_CHICK Isoform 1 of Prefoldin subunit 4 OS=Gallus gallus OX=9031 GN=PFDN4 PE=1 SV=3 CANONICAL=F1NP43-1" }, "isoforms": [ { "isoform_ac": "F1NP43-1", "url": "https://www.uniprot.org/uniprotkb/F1NP43/entry#F1NP43-1", "sequence": { "sequence": "MAATMKKAAAEDVNVTFEDQQKINKFARNTSRITELKEEIEVKKKQLQNLEDACDDIMMLDDDSLLIPYQIGDVFISHSQEETQEMLEEAKKSLQEEIETLESRVESIQRVLSDLKVQLYAKFGNNINLEAEDS", "length": 134, "header": "tr|F1NP43-1|F1NP43_CHICK Isoform 1 of Prefoldin subunit 4 OS=Gallus gallus OX=9031 GN=PFDN4 PE=1 SV=3 CANONICAL=F1NP43-1" }, "locus": { "chromosome": "20", "start_pos": 12679245, "end_pos": 12677903, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010036481.1", "url": "https://www.ensembl.org/id/ENSGALT00010036481.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021236.1", "url": "https://www.ensembl.org/id/ENSGALP00010021236.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:419337", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419337", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A5G2QBU9-1", "protein_name": "Prefoldin subunit 4", "gene_name": "PFDN4", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "IAAAAEDVNVTFEDQQKINKFARNTSRITELKEEIEVKKKQLQNLEDACEDIMLADDDCLMIPYQIGDVFISHSQEETQEMLEEAKKNLQEEIDALESRVASIQRVLADLKVQLYAKFGSNINLEADES", "length": 129 }, "evidence": [ { "id": "F1NP43", "url": "https://omabrowser.org/oma/group/F1NP43/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1R0Z8-1", "protein_name": "Prefoldin subunit 4", "gene_name": "pfdn4", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAATMKKGVAAEDVNVTFEDQQKINKFARNTNRMSELKDEIEAKKKSLQNLEDASDDLMMCEDDSMLIPYQIGDVFISHSQEETQEMLEAAKEALQEEIKALEGRVSSIQGVLGDLKVQLYAKFGNNINLEADES", "length": 135 }, "evidence": [ { "id": "F1NP43", "url": "https://omabrowser.org/oma/group/F1NP43/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q2TBR6-1", "protein_name": "Prefoldin subunit 4", "gene_name": "PFDN4", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAATMKKAAAEDVNVTFEDQQKINKFARNTSRITELKEEIEVKKKQLQNLEDACEDIMLADDDCLMIPYQIGDVFISHSQEETQEMLEEAKKNLQEEIDALESRVESIQRVLADLKVQLYAKFGSNINLEADES", "length": 134 }, "evidence": [ { "id": "F1NP43", "url": "https://omabrowser.org/oma/group/F1NP43/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q9NQP4-1", "protein_name": "Prefoldin subunit 4", "gene_name": "PFDN4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAATMKKAAAEDVNVTFEDQQKINKFARNTSRITELKEEIEVKKKQLQNLEDACDDIMLADDDCLMIPYQIGDVFISHSQEETQEMLEEAKKNLQEEIDALESRVESIQRVLADLKVQLYAKFGSNINLEADES", "length": 134 }, "evidence": [ { "id": "F1NP43", "url": "https://omabrowser.org/oma/group/F1NP43/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1NP43", "url": "https://www.uniprot.org/uniprotkb/F1NP43" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1NP43", "url": "https://www.uniprot.org/uniprotkb/F1NP43" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "F1NP43", "url": "https://www.uniprot.org/uniprotkb/F1NP43" } ], "pmid": "" }, { "name": "prefoldin complex", "id": "GO:0016272", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016272", "evidence": [ { "database": "UniProtKB", "id": "F1NP43", "url": "https://www.uniprot.org/uniprotkb/F1NP43" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "unfolded protein binding", "id": "GO:0051082", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051082", "evidence": [ { "database": "UniProtKB", "id": "F1NP43", "url": "https://www.uniprot.org/uniprotkb/F1NP43" } ], "pmid": "" }, { "name": "amyloid-beta binding", "id": "GO:0001540", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001540", "evidence": [ { "database": "UniProtKB", "id": "F1NP43", "url": "https://www.uniprot.org/uniprotkb/F1NP43" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "protein folding", "id": "GO:0006457", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006457", "evidence": [ { "database": "UniProtKB", "id": "F1NP43", "url": "https://www.uniprot.org/uniprotkb/F1NP43" } ], "pmid": "" }, { "name": "negative regulation of amyloid fibril formation", "id": "GO:1905907", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905907", "evidence": [ { "database": "UniProtKB", "id": "F1NP43", "url": "https://www.uniprot.org/uniprotkb/F1NP43" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 14, "end_pos": 16, "annotation": "n_glycosylation_sequon" }, { "start_pos": 29, "end_pos": 31, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1NP43-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 134, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1NP43-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1NP43" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 14, "end_pos": 16 }, { "start_pos": 29, "end_pos": 31 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1NP57-1", "uniprot_ac": "F1NP57", "uniprot_id": "F1NP57_CHICK", "mass": { "chemical_mass": 150286.0, "monoisotopic_mass": 150286.0 }, "refseq": { "ac": "NP_989961", "name": "adenylate cyclase type 9", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989961" }, "gene_names": [ { "name": "ADCY9", "type": "recommended", "evidence": [ { "id": "F1NP57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NP57" } ] }, { "name": "AC9", "type": "synonym", "evidence": [ { "id": "NP_989961", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989961" } ] }, { "name": "ADCY9", "type": "synonym", "evidence": [ { "id": "NP_989961", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989961" } ] } ], "protein_names": [ { "name": "Adenylate cyclase type 9", "type": "recommended", "evidence": [ { "id": "F1NP57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NP57/entry#names_and_taxonomy" } ] }, { "name": "4.6.1.1", "type": "synonym", "evidence": [ { "id": "F1NP57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NP57/entry#names_and_taxonomy" } ] }, { "name": "ATP pyrophosphate-lyase 9", "type": "synonym", "evidence": [ { "id": "NP_989961", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989961" }, { "id": "F1NP57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NP57/entry#names_and_taxonomy" } ] }, { "name": "Adenylate cyclase type IX", "type": "synonym", "evidence": [ { "id": "F1NP57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NP57/entry#names_and_taxonomy" } ] }, { "name": "Adenylyl cyclase 9", "type": "synonym", "evidence": [ { "id": "F1NP57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NP57/entry#names_and_taxonomy" } ] }, { "name": "adenylate cyclase type 9", "type": "synonym", "evidence": [ { "id": "NP_989961", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989961" } ] }, { "name": "adenylate cyclase type IX", "type": "synonym", "evidence": [ { "id": "NP_989961", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989961" } ] }, { "name": "adenylyl cyclase 9", "type": "synonym", "evidence": [ { "id": "NP_989961", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989961" } ] }, { "name": "adenylyl cyclase type IX", "type": "synonym", "evidence": [ { "id": "NP_989961", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989961" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ401469.1, SRR13267652.19233.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA103992290, SAMEA103992323 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000257.1. On Jan 4, 2015 this sequence version replaced NP_989961.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_989961", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989961" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NP57", "url": "https://www.uniprot.org/uniprotkb/F1NP57" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ADCY9", "url": "https://www.uniprot.org/uniprotkb/F1NP57", "locus": { "chromosome": "14", "start_pos": 12596671, "end_pos": 12655700, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010016544", "url": "https://www.ensembl.org/id/ENSGALG00010016544" } ] } } ], "crossref": [ { "id": "ENSGALG00000007779", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000007779", "database": 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"https://omabrowser.org/oma/group/FTAMPPG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1L1RTJ6", "url": "https://www.orthodb.org/?gene=A0A1L1RTJ6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YWQ5", "url": "https://www.orthodb.org/?gene=A0A8V0YWQ5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NP57", "url": "https://www.orthodb.org/?gene=F1NP57", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45627", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45627", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45627:SF8", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45627:SF8", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00211", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00211", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-163615", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-163615", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-170660", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-170660", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-170670", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-170670", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-418597", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-418597", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-5610787", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5610787", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_989961", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989961", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "15389", "url": "https://www.rhea-db.org/rhea/15389", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A1L1RTJ6", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RTJ6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1L1RTJ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RTJ6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YWQ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YWQ5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YWQ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YWQ5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NP57", "url": "https://www.uniprot.org/uniprotkb/F1NP57", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NP57-1", "url": "https://www.uniprot.org/uniprotkb/F1NP57-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASPPHQQLLHHHSTEVSCDSSGDSNSVTVRINPRQQQGCSSAKRCKYSISSSCSSGESGGARRAGGGGGPGLRRQKKLPQLFERASSRWWDPKFDSTNLEEACMERCFPQTQRRFRYALFYIGSACLLWGIYFGVHMREKQMVFMVPALCFLLVCVAFFAFTFTKAYARRYVWTSLTLTLLVFALTLAPQFQALDPLSGSGDASNRTAPAAPVDTCLSQVGSFSMCVEVLLLLYTVMHLPLYLSLFLGLSYSVLFETFGYRFRDESCFTPLGGGAVYWELLSKAFLHVCIHAIGIHLFIMSEVRSRSTFLKVGQSIMHGKDLEVEKALKERMIHSVMPRIIADDLMKQGDDESENSIKRHSTSSPKNRKKKPSIQKTPIIFRPFKMQQIEQVSILFADIVGFTKMSANKSAHALVGLLNDLFGRFDRLCEDTKCEKISTLGDCYYCVAGCPEPRADHAYCCIEMGLGMIKAIEQFCQEKKEMVNMRVGVHTGTVLCGILGMRRFKFDVWSNDVNLANLMEQLGVAGKVHISEATAKYLDDRYEMEDGKVTERVGQSVVADQLKGLKTYLISGQKVKEPHCSCSQALLPSLEAGDGARMQAAPSAENAADSTKALKHVEKPKPCPSCSTTLVPPCDVSIDEGAIQNGCQDEHKNSTKAPGGHSPKTQNGLLSPPQEEKLSNSQTSLYEMLQEKGRWGGVSLDQSALLPLRFKNIREKTDAHFVDVIKEDSLMKDYFFKPPISKLSLNFLDQDLEMAYRTSYQEEVMRNAPVKTFASATFSSLLDVFLSTTVFLILSVTCFLKHGMVASPPPPAAVVVFVIAILLEVLSLVISVRMVFFLEEVMACTKRLLELISGWLPRHFLGAILVSLPALAVFSHFTSDFETNIHYTMFMCCAILIAIVQYCNFCQLSSWMRSLLATVVGAVLLILLYVSLCPDSSVETLHLDLAQNLSSRKSPCNSSMPADVKRPADLIGQEVILVVFLLLLLVWFLNREFEVSYRLHYHGDVEADLHRTKIQSMRDQADWLLRNIIPYHVAEQLKVSQSYSKNHDSGGVIFASIVNFSEFYEENYEGGKECYRVLNELIGDFDELLSKPHYSSIEKIKTIGATYMAASGLNTSQCQDSNHPHGHLQTLFEFAKEMMRVVDDFNNNMLWFNFKLRIGFNHGPLTAGVIGTTKLLYDIWGDTVNIASRMDTTGVECRIQVSEESYRILSKMGYDFDYRGTVNVKGKGQMKTYLYPKCMDNGIVPHHQLSISPDIRVQVDGSIGRSPTDEIANLVPSVQNSDKTAHGTDNSETKDALPSSKKLQKEPTKAEERCRFGKAVEKTDCEEAGTEEVNELTKLNVSKSV", "length": 1346, "header": "tr|F1NP57-1|F1NP57_CHICK Isoform 1 of Adenylate cyclase type 9 OS=Gallus gallus OX=9031 GN=ADCY9 PE=3 SV=3 CANONICAL=F1NP57-1" }, "isoforms": [ { "isoform_ac": "A0A1L1RTJ6-1", "url": "https://www.uniprot.org/uniprotkb/F1NP57/entry#A0A1L1RTJ6-1", "sequence": { "sequence": "MASPPHQQLLHHHSTEVSCDSSGDSNSVTVRINPRQQQGCSSAKRCKYSISSSCSSGESGGARRAGGGGGPGLRRQKKLPQLFERASSRWWDPKFDSTNLEEACMERCFPQTQRRFRYALFYIGSACLLWGIYFGVHMREKQMVFMVPALCFLLVCVAFFAFTFTKAYARRYVWTSLTLTLLVFALTLAPQFQALDPLSGSGDASNRTAPAAPVDTCLSQVGSFSMCVEVLLLLYTVMHLPLYLSLFLGLSYSVLFETFGYRFRDESCFTPLGGGAVYWELLSKAFLHVCIHAIGIHLFIMSEVRSRSTFLKVGQSIMHGKDLEVEKALKERMIHSVMPRIIADDLMKQGDDESENSIKRHSTSSPKNRKKKPSIQKTPIIFRPFKMQQIEQVSILFADIVGFTKMSANKSAHALVGLLNDLFGRFDRLCEDTKCEKISTLGDCYYCVAGCPEPRADHAYCCIEMGLGMIKAIEQFCQEKKEMVNMRVGVHTGTVLCGILGMRRFKFDVWSNDVNLANLMEQLGVAGKVHISEATAKYLDDRYEMEDGKVTERVGQSVVADQLKGLKTYLISGQKVKEPHCSCSQALLPSLEAGDGARMQAAPSAENAADSTKALKHVEKPKAPGGHSPKTQNGLLSPPQEEKLSNSQTSLYEMLQEKGRWGGVSLDQSALLPLRFKNIREKTDAHFVDVIKEDSLMKDYFFKPPISKLSLNFLDQDLEMAYRTSYQEEVMRNAPVKTFASATFSSLLDVFLSTTVFLILSVTCFLKHGMVASPPPPAAVVVFVIAILLEVLSLVISVRMVFFLEEVMACTKRLLELISGWLPRHFLGAILVSLPALAVFSHFTSDFETNIHYTMFMCCAILIAIVQYCNFCQLSSWMRSLLATVVGAVLLILLYVSLCPDSSVETLHLDLAQNLSSRKSPCNSSMPADVKRPADLIGQEVILVVFLLLLLVWFLNREFEVSYRLHYHGDVEADLHRTKIQSMRDQADWLLRNIIPYHVAEQLKVSQSYSKNHDSGGVIFASIVNFSEFYEENYEGGKECYRVLNELIGDFDELLSKPHYSSIEKIKTIGATYMAASGLNTSQCQDSNHPHGHLQTLFEFAKEMMRVVDDFNNNMLWFNFKLRIGFNHGPLTAGVIGTTKLLYDIWGDTVNIASRMDTTGVECRIQVSEESYRILSKMGYDFDYRGTVNVKGKGQMKTYLYPKCMDNGIVPHHQLSISPDIRVQVDGSIGRSPTDEIANLVPSVQNSDKTAHGTDNSETKDALPSSKKLQKEPTKAEERCRFGKAVEKTDCEEAGTEEVNELTKLNVSKSV", "length": 1311, "header": "tr|A0A1L1RTJ6-1|A0A1L1RTJ6_CHICK Computationally mapped isoform of Adenylate cyclase type 9 OS=Gallus gallus OX=9031 GN=ADCY9 PE=3 SV=2 CANONICAL=F1NP57-1" }, "locus": { "chromosome": "14", "start_pos": 12655433, "end_pos": 12597648, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010039864.1", "url": "https://www.ensembl.org/id/ENSGALT00010039864.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023072.1", "url": "https://www.ensembl.org/id/ENSGALP00010023072.1" } ] } }, { "isoform_ac": "A0A8V0YWQ5-1", "url": "https://www.uniprot.org/uniprotkb/F1NP57/entry#A0A8V0YWQ5-1", "sequence": { "sequence": "MASPPHQQLLHHHSTEVSCDSSGDSNSVTVRINPRQQQGCSSAKRCKYSISSSCSSGESGGARRAGGGGGPGLRRQKKLPQLFERASSRWWDPKFDSTNLEEACMERCFPQTQRRFRYALFYIGSACLLWGIYFGVHMREKQMVFMVPALCFLLVCVAFFAFTFTKAYARRYVWTSLTLTLLVFALTLAPQFQALDPLSGSGDASNRTAPAAPVDTCLSQVGSFSMCVEVLLLLYTVMHLPLYLSLFLGLSYSVLFETFGYRFRDESCFTPLGGGAVYWELLSKAFLHVCIHAIGIHLFIMSEVRSRSTFLKVGQSIMHGKDLEVEKALKERMIHSVMPRIIADDLMKQGDDESENSIKRHSTSSPKNRKKKPSIQKTPIIFRPFKMQQIEQVSILFADIVGFTKMSANKSAHALVGLLNDLFGRFDRLCEDTKCEKISTLGDCYYCVAGCPEPRADHAYCCIEMGLGMIKAIEQFCQEKKEMVNMRVGVHTGTVLCGILGMRRFKFDVWSNDVNLANLMEQLGVAGKVHISEATAKYLDDRYEMEDGKVTERVGQSVVADQLKGLKTYLISGQKVKEPHCSCSQALLPSLEAGDGARMQAAPSAENAADSTKALKHVEKPKPCPSCSTTLVPPCDVSIDEGAIQNGCQDEHKNSTKAPGGHSPKTQNGLLSPPQEEKLSNSQTSLYEMLQEKGRWGGVSLDQSALLPLRFKNIREKTDAHFVDVIKEDSLMKDYFFKPPISKLSLNFLDQDLEMAYRTSYQEEVMRNAPVKTFASATFSSLLDVFLSTTVFLILSVTCFLKHGMVASPPPPAAVVVFVIAILLEVLSLVISVRMVFFLEEVMACTKRLLELISGWLPRHFLGAILVSLPALAVFSHFTSDFETNIHYTMFMCCAILIAIVQYCNFCQLSSWMRSLLATVVGAVLLILLYVSLCPDSSVETLHLDLAQNLSSRKSPCNSSMPADVKRPADLIGQEVILVVFLLLLLVWFLNREFEVSYRLHYHGDVEADLHRTKIQSMRDQADWLLRNIIPYHVAEQLKVSQSYSKNHDSGGVIFASIVNFSEFYEENYEGGKECYRVLNELIGDFDELLSKPHYSSIEKIKTIGATYMAASGLNTSQCQDSNHPHGHLQTLFEFAKEMMRVVDDFNNNMLWFNFKLRIGFNHGPLTAGVIGTTKLLYDIWGDTVNIASRMDTTGVECRIQTFGFRWTAALGGLPPMRLPTWCLLYRILIRQPTAQITQKPRMLFLPPRSSRKSRRKQKRGAGLAKL", "length": 1267, "header": "tr|A0A8V0YWQ5-1|A0A8V0YWQ5_CHICK Computationally mapped isoform of Adenylate cyclase type 9 OS=Gallus gallus OX=9031 GN=ADCY9 PE=3 SV=1 CANONICAL=F1NP57-1" }, "locus": { "chromosome": "14", "start_pos": 12655433, "end_pos": 12597725, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010039851.1", "url": "https://www.ensembl.org/id/ENSGALT00010039851.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023063.1", "url": "https://www.ensembl.org/id/ENSGALP00010023063.1" } ] } }, { "isoform_ac": "F1NP57-1", "url": "https://www.uniprot.org/uniprotkb/F1NP57/entry#F1NP57-1", "sequence": { "sequence": "MASPPHQQLLHHHSTEVSCDSSGDSNSVTVRINPRQQQGCSSAKRCKYSISSSCSSGESGGARRAGGGGGPGLRRQKKLPQLFERASSRWWDPKFDSTNLEEACMERCFPQTQRRFRYALFYIGSACLLWGIYFGVHMREKQMVFMVPALCFLLVCVAFFAFTFTKAYARRYVWTSLTLTLLVFALTLAPQFQALDPLSGSGDASNRTAPAAPVDTCLSQVGSFSMCVEVLLLLYTVMHLPLYLSLFLGLSYSVLFETFGYRFRDESCFTPLGGGAVYWELLSKAFLHVCIHAIGIHLFIMSEVRSRSTFLKVGQSIMHGKDLEVEKALKERMIHSVMPRIIADDLMKQGDDESENSIKRHSTSSPKNRKKKPSIQKTPIIFRPFKMQQIEQVSILFADIVGFTKMSANKSAHALVGLLNDLFGRFDRLCEDTKCEKISTLGDCYYCVAGCPEPRADHAYCCIEMGLGMIKAIEQFCQEKKEMVNMRVGVHTGTVLCGILGMRRFKFDVWSNDVNLANLMEQLGVAGKVHISEATAKYLDDRYEMEDGKVTERVGQSVVADQLKGLKTYLISGQKVKEPHCSCSQALLPSLEAGDGARMQAAPSAENAADSTKALKHVEKPKPCPSCSTTLVPPCDVSIDEGAIQNGCQDEHKNSTKAPGGHSPKTQNGLLSPPQEEKLSNSQTSLYEMLQEKGRWGGVSLDQSALLPLRFKNIREKTDAHFVDVIKEDSLMKDYFFKPPISKLSLNFLDQDLEMAYRTSYQEEVMRNAPVKTFASATFSSLLDVFLSTTVFLILSVTCFLKHGMVASPPPPAAVVVFVIAILLEVLSLVISVRMVFFLEEVMACTKRLLELISGWLPRHFLGAILVSLPALAVFSHFTSDFETNIHYTMFMCCAILIAIVQYCNFCQLSSWMRSLLATVVGAVLLILLYVSLCPDSSVETLHLDLAQNLSSRKSPCNSSMPADVKRPADLIGQEVILVVFLLLLLVWFLNREFEVSYRLHYHGDVEADLHRTKIQSMRDQADWLLRNIIPYHVAEQLKVSQSYSKNHDSGGVIFASIVNFSEFYEENYEGGKECYRVLNELIGDFDELLSKPHYSSIEKIKTIGATYMAASGLNTSQCQDSNHPHGHLQTLFEFAKEMMRVVDDFNNNMLWFNFKLRIGFNHGPLTAGVIGTTKLLYDIWGDTVNIASRMDTTGVECRIQVSEESYRILSKMGYDFDYRGTVNVKGKGQMKTYLYPKCMDNGIVPHHQLSISPDIRVQVDGSIGRSPTDEIANLVPSVQNSDKTAHGTDNSETKDALPSSKKLQKEPTKAEERCRFGKAVEKTDCEEAGTEEVNELTKLNVSKSV", "length": 1346, "header": "tr|F1NP57-1|F1NP57_CHICK Isoform 1 of Adenylate cyclase type 9 OS=Gallus gallus OX=9031 GN=ADCY9 PE=3 SV=3 CANONICAL=F1NP57-1" }, "locus": { "chromosome": "14", "start_pos": 12655433, "end_pos": 12597648, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010039861.1", "url": "https://www.ensembl.org/id/ENSGALT00010039861.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023069.1", "url": "https://www.ensembl.org/id/ENSGALP00010023069.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "gga:395339", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:395339", "resource": "KEGG Pathway" }, { "id": "R-GGA-163615", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-163615", "resource": "Reactome", "description": "PKA activation" }, { "id": "R-GGA-170660", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-170660", "resource": "Reactome", "description": "Adenylate cyclase activating pathway" }, { "id": "R-GGA-170670", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-170670", "resource": "Reactome", "description": "Adenylate cyclase inhibitory pathway" }, { "id": "R-GGA-418597", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-418597", "resource": "Reactome", "description": "G alpha (z) signalling events" }, { "id": "R-GGA-5610787", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5610787", "resource": "Reactome", "description": "Hedgehog 'off' state" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287B2U1-1", "protein_name": "Adenylate cyclase type 9", "gene_name": "ADCY9", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MASPPHQQLLQHHSTEVSCDSSGDSNSVRVKINPKQLSSNSHPKHCKYSISSSCSSSGDSGGVPRRMGARGRLRRRKKLPQLFERASSRWWDPKFDSVNLEEACMERCFPQTQRRFRYALFYIGFACLLWSIYFGVHMSSRLLVMAAPALCFLGVCVGFFLFTFTKLYARHYVWTSLVLTLLVFALTLAAQFQVSTPLSGRVDSSNQTRAARPTDTCLSQIGGFSMCIEVLFLLYTVMHLPLYLSLILGVAYSVLFETFGYHFRDEACFPLPGAGALQWELLSRALLHVCIHAIGIHLFIMSQVRSRSTFLKVGQSIMHGKDLEVEKALKERMIHSVMPRIIADDLMKQGDEESENSVKRHATSSPKNRKKKSSIQKAPIAFRPFKMQQIEEVSILFADIVGFTKMSANKSAHALVGLLNDLFGRFDRLCEETKCEKISTLGDCYYCVAGCPEPRADHAYCCIEMGLGMIRAIEQFCQEKKEMVNMRVGVHTGTVLCGILGMRRFKFDVWSNDVNLANLMEQLGVAGKVHISEATAKYLDDRYEMEDGRVNERLGQSVVADQLKGHSFRLCSVAFLFPLPAFHHSAQVLTFGLKTYLIAGQRAKESHCSCSEALLSGFEVIDGSRVSSGPRGQGTASPGSVSDLAQTVKTFDNLKTCPSCGITFAPKWEAGAEGGAVQNGCQEEPKNGTKASGGAGSKAQNGLLSPPPEEKLSNSHTSLCEILQEKGRWAGVSLDQSALLPLRFKNIREKTDAHFVDVIKEDSLMKDYFFKPPINQFSLNFLDQELERAYRTSYQEEVVKSSPVKTFASATFSSLLDVFLSTTVFLILSITCFLKYGANATPPQPAALAVFAAALLLEVLSLGVSVRMAFFLEDVMACTKRLLEWIAGWLPHHCIGAILVSLPALAVYSHVTSKFEMDIHSTVFTGSAVLIAVVHYCNFCQLSSWMRSSLATVVGAGPLLLLYASLCPDSSIVISHLDAVQNFSSAGKPCNASLPPDSRSPARLIGQEVVLVFFLLLLLVWFLNREFEVSYRLHYHGDVEADLHRTKIQSMRDQADWLLRNIIPYHVAEQLKVSQTYSKNHDSGGVIFASIVNFGEFYEENYEGGKECYRVLNELIGDFDELLSKPDYSSIEKIKTIGATYMAASGLNATQGRDSSHPQEHLQVLFEFAREMMRVVDDFNNNMLWFNFKLRVGFNHGPLTAGVIGTTKLLYDIWGDTVNIASRMDTTGVECRIQVSEESYRVLSKMGYDFDYRGTVNVKGKGQMKTYLYPRCSDHGLVPQHQLSISPDIRVQVDGSIGRSPTDEIANLVPSVQTSDQASPASDNTPARDAPPSAKRPWREPGKAEERCRFGKAIEKSDCEESGAEDTDELTKLSVCRRA", "length": 1379 }, "evidence": [ { "id": "F1NP57", "url": "https://omabrowser.org/oma/group/F1NP57/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A9J7GD34-1", "protein_name": "Adenylate cyclase type 9", "gene_name": "Adcy9", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MASSPHQQLLHHHSTEVSCDSSGDSNSVRVKINPKQLSSNTHPKHCKYSISSSCSSSGDSGGLPRRMGGGGRLRRQKKLPQLFERASSRWWDPKFDSVNLEEACLERCFPQTQRRFRYALFYVGFACLLWSIYFAVHMRSKVIVMVVPALCFLVVCVGFFLFTFTKLYARHYAWTSLALTLLVFALTLAAQFQVWTPLLGRVDSSNQTLIAKAAADTCLSQVGLFSMCIEVLFLLYTVMHLPLYLSLFLGVAYSVLFETFGYHFRNEDCFPSPGPGALHWELLSRALLHVCIHAIGIHLFVMSQVRSRSTFLKVGQSIMHGKDLEVEKALKERMIHSVMPRIIADDLMKQGDEESENSVKRHTTSSPKNRKKKSSIQKAPIAFRPFKMQQIEEVSILFADIVGFTKMSANKSAHALVGLLNDLFGRFDRLCEETKCEKISTLGDCYYCVAGCPEPRADHAYCCIEMGLGMIKAIEQFCQEKKEMVNMRVGVHTGTVLCGILGMRRFKFDVWSNDVNLANLMEQLGVAGKVHISEATAKYLDDRYEMEDGRVIERLGQSVVADQLKGLKTYLISGQRAKESHCSCAEALLSGFEVIDGSRASSGPRGQGTASPGSVSDLAQTVKTFDNLKTCPACGITFAPKSEAGAEGGAVQNGCQDEPKTGTKVTSSWLLFLSVPLLAHPPKASGGPNSKTQNGLLSPPPEEKLTNSQTSLCEILQEKGRWAGVSLDQSALLPLRFKNIREKTDAHFVDVIKEDSLMKDYFFKPPINQFSLNFLDQELERSYRTSYQEEVIKNSPVKTFASATFSSLLDVFLSTTVFLILSITCFLKYAATATPPPPAALAVFGADLLLEVLSLVVSIRMVFFLEDVMVCTKRLLEWIAGWLPRHCIGAILVSLPALAVYSHITSEFETNIHFTMFTGSAVLVAVVHYCNFCQLSSWMRSSLATIVGAGPLLLLYISLCRDSSIVISPLDTAQNFSANRNPCNSSLLQDSRRPASLIGKELALTFFLLLLLVWFLNREFEVSYRLHYHGDVEADLHRTKIQSMRDQADWLLRNIIPYHVAEQLKVSQTYSKNHDSGGVIFASIVNFSEFYEENYEGGKECYRVLNELIGDFDELLSKPDYNSIEKIKTIGATYMAASGLNTAQCQEGGHPQEHLRILFEFAKEMMRVVDDFNNNMLWFNFKLRVGFNHGPLTAGVIGTTKLLYDIWGDTVNIASRMDTTGVECRIQVSEESYRVLSKMGYDFDYRGTVNVKGKGQMKTYLYPKCMDNGVVPQHQLSISPDIRVQVDGSIGRSPTDEIANLVPSVQYTDKTSLGSDDNTQAKEVHLSCKRPWREPVKAEERFRFGKAIEKDDCEDTGIEEANELTKLNVSKSV", "length": 1373 }, "evidence": [ { "id": "F1NP57", "url": "https://omabrowser.org/oma/group/F1NP57/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "M0R5U4-1", "protein_name": "Adenylate cyclase type 9", "gene_name": "Adcy9", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASSPHQQLLHHHSTEVSCDSSGDSNSVRVKINPKQLSSNTHPKHCKYSISSSCSSSGDSGGLPRRVGGGGRLRRQKKLPQLFERASSRWWDPKFDSVNLEEACLERCFPQTQRRFRYALFYVGFACLLWSIYFAVHMRSKVIVMVVPALCFLVVCVGFFLFTFTKLYARHYAWTSLALTLLVFALTLAAQFQVWTPLSGRVDSPNHTLTAKAADTCLSQVGSFSMCIEVLFLLYTVMHLPLYLSLFLGVVYSVLFETFGYHFRNEDCFPSPDPGALHWELLSRALLHVCIHAIGIHLFVMSQVRSRSTFLKVGQSIMHGKDLEVEKALKERMIHSVMPRIIADDLMKQGDEESENSVKRHATSSPKNRKKKASIQKAPIAFRPFKMQQIEEVSILFADIVGFTKMSANKSAHALVGLLNDLFGRFDRLCEETKCEKISTLGDCYYCVAGCPEPRADHAYCCIEMGLGMIKAIEQFCQEKKEMVNMRVGVHTGTVLCGILGMRRFKFDVWSNDVNLANLMEQLGVAGKVHISEATAKYLDDRYEMEDGRVMERLGQSVVADQLKGLKTYLISGQRAKESHCSCAEALLSGFEVIDDSRVSSGPRGQGTASPGSVSDLAQTVKTFDNLKTCPSCGITFAPKSEAGAEGGAVQNGCQDEPKASTKVTSSWLLFLSVPLLAHPPKASGGPNSKTQNGLLSPPAEEKLTNSQTSLCEILQEKGRWAGVSLDQSALLPLRFKNIREKTDAHFVDVIKEDSLMKDYFFKPPISQFSLNFLDQELEQSYRASYQEEVIKNSPVKTFASATFSSLLDVFLSTTVFLILSITCFLKYGATATPPPPAALAVFGADLLLEVLSLIVSIRMVFFLEDVLTCTKRLLEWIAGWLPRHCIGAILVSLPALAVYSHITSEFETNINFTMLTGSAVLVAVVHYCNFCQLSSWMRSSLATLVGAGPLLLLYISLCQDSSIVMSPLDTAQNFSASERSPCNSSVLQDGRRPASLIGKELILTFFLLLLLVWFLNREFEVSYRLHYHGDVEADLHRTKIQSMRDQADWLLRNIIPYHVAEQLKVSQTYSKNHDSGGVIFASIVNFSEFYEENYEGGKECYRVLNELIGDFDELLSKPDYNSIEKIKTIGATYMAASGLNTAQCQEGGHPQEHLRILFEFAKEMMRVVDDFNNNMLWFNFKLRVGFNHGPLTAGVIGTTKLLYDIWGDTVNIASRMDTTGVECRIQVSEESYRVLSKMGYDFDYRGTVNVKGKGQMKTYLYPKCTDNGVVPQHQLSISPDIRVQVDGSIGRSPTDEITNLVPSVQYLDKASLGSDDGAQTKEATLSSKRPWREPVKAEERFRFGKAIEKEDCEDTGAEEANELTKLNVSKSV", "length": 1373 }, "evidence": [ { "id": "F1NP57", "url": "https://omabrowser.org/oma/group/F1NP57/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M9PEP2-1", "protein_name": "Adenylate cyclase type 9", "gene_name": "Ac13E", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSESRRQSVSSRAMPPGVLVNDSRANSTDDIQIALAPHIQTYLSQTGRRHSCCSVMLPVAFERAAAKSWLDPKFDSPVLEEQYQASVFPHVRMRYRFTLSYILLCSLMWCLYFVVDGGSEDFWRPISSSFSMLSLVTIMALCFTHWDLYREHRTVTSAVTALLLCGASLAFLTYTGRAFSPLGHFAICLEIVLLIYTALPMPLWLGASTAISYSIAFEMVSHMVIGCSAIHGGPMHGGGGAAGGSGMEANGDPSNRILILRIMAHLSVHLVGVHVLIMNLVRMRGTFMKVGQNLLVRRQLEMEKQLKEKMIHSVMPPKVADMLLNEGGPSGLDAGGLPPESHYMRPRASNDVKSLFRPFHMHSMENVSILFADIVGFTRMSSTKTAEQLVEILNDLFERFDDLCSLSGCEKISTLGDCYYCVSGCPEPRADHAICCVEMGLGMIDAMRCFDAQRHEGVKMRVGVHTGTVLCGIVGTRRVKFDVWSNDVSLANKMESSGKPEQVHISQETSSFLGDAYYLEEGEEVFGHRTYFVVGRRRDFTRTNSLSPSMPANATGSSLLLPGAHGASLSQSATNVSAVQPNVPPASPVGQLSSSLNPSPVLSMRPRLTSLSMKMRKKSQSRDRDVERGIIHPAAAGIPPVIVVRERPKIIITTKSLPGSLDSDEQPPVSPPLLPPANPPAAETRSKIKLKVWKIPRFLKRFEDLTNRSSCGGSSSAGHLDKEREREREKEKEELHQHNQLNPEETLAFMDNQMQNGNGCGYQQLPVLVESNHRTQTLDIPAARPVLHHAATSTALASSVLRSPEAGVSGGGGCCSPGQYSMYDDIIDVRSYISQSRSDISPFGRSGSYRSQCGRQSTGGVNGAGPAGVGAEGRAGTSQTAPPVEQSPLPRPRASTLATGRPTPNSLEPGPSSTSPCCLPAPGNSVGGGGIFPPTHSRQSSICPSATSRKDSGIKSNSRRSSIQQQIYALNQTAISQHRVSGYFTSSTSSISNLGEVQGLGLPLAVQPPPPLLMPACSSQMADPLAACLQQLRKQSDLQLIRCVRDNARSQRSYLVKPPLRKFSLYFKSRQLERDFRSKAHRFGAENETEGPPTLATPRYNTYIDIFVGIAVYLCISVSLFLMTQNTVSPSFRLWVTLFSCFTGIQVFALFLFTRQMCRRQSGSNVSNRFRSKSTTSEDLERDERGAAPGGRPHFESCADRIFEAISSWYPWHICLAVLMAMPVLLIIANFLLLDLEQLEAFEYHYGFLIFVCIVHFCNFTQLNCWVRNVLAFLAALCFIGIAVSQLMVYSHNRSDQQQDQEASNFIQEIKWFQDYHVEIYLDLLLILVLVWFLNREFEIGYRLTFYGNAVANQDKVRVQNMKNQADMLLHNIIPKHVAEHLKNTAKYSENHHNIAIIFASIVNFNEMYDESYLGGKEFLRVLNELIGDFDELLSRPEFRAVEKIKTIGSTFMAASGLDPSHRGTGDEHIHTLMEFSIAMQEVVDAFNKDLLEFNLILRIGMNIGDVTAGVIGTSKLYYDIWGDAVNVASRMDSTGLPNRIQVGKDCLPFLTNRYEFEPRGSVYVKGKDHMEVFLYTTRRDNPLDDDEADKVEQLGTKKMEHEGRDEDVVQGEQQAEDKDEEEEEEEEDDDLHSSETTTLFKSQESLQANGGSHLAPNAAATSHTHTITLTNNNNHNSSNINNNIATSNTTTTANNNSMPVET", "length": 1703 }, "evidence": [ { "id": "F1NP57", "url": "https://omabrowser.org/oma/group/F1NP57/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "O60503-1", "protein_name": "Adenylate cyclase type 9", "gene_name": "ADCY9", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MASPPHQQLLHHHSTEVSCDSSGDSNSVRVKINPKQLSSNSHPKHCKYSISSSCSSSGDSGGVPRRVGGGGRLRRQKKLPQLFERASSRWWDPKFDSVNLEEACLERCFPQTQRRFRYALFYIGFACLLWSIYFAVHMRSRLIVMVAPALCFLLVCVGFFLFTFTKLYARHYAWTSLALTLLVFALTLAAQFQVLTPVSGRGDSSNLTATARPTDTCLSQVGSFSMCIEVLFLLYTVMHLPLYLSLCLGVAYSVLFETFGYHFRDEACFPSPGAGALHWELLSRGLLHGCIHAIGVHLFVMSQVRSRSTFLKVGQSIMHGKDLEVEKALKERMIHSVMPRIIADDLMKQGDEESENSVKRHATSSPKNRKKKSSIQKAPIAFRPFKMQQIEEVSILFADIVGFTKMSANKSAHALVGLLNDLFGRFDRLCEETKCEKISTLGDCYYCVAGCPEPRADHAYCCIEMGLGMIKAIEQFCQEKKEMVNMRVGVHTGTVLCGILGMRRFKFDVWSNDVNLANLMEQLGVAGKVHISEATAKYLDDRYEMEDGKVIERLGQSVVADQLKGLKTYLISGQRAKESRCSCAEALLSGFEVIDGSQVSSGPRGQGTASSGNVSDLAQTVKTFDNLKTCPSCGITFAPKSEAGAEGGAPQNGCQDEHKNSTKASGGPNPKTQNGLLSPPQEEKLTNSQTSLCEILQEKGRWAGVSLDQSALLPLRFKNIREKTDAHFVDVIKEDSLMKDYFFKPPINQFSLNFLDQELERSYRTSYQEEVIKNSPVKTFASPTFSSLLDVFLSTTVFLTLSTTCFLKYEAATVPPPPAALAVFSAALLLEVLSLAVSIRMVFFLEDVMACTKRLLEWIAGWLPRHCIGAILVSLPALAVYSHVTSEYETNIHFPVFTGSAALIAVVHYCNFCQLSSWMRSSLATVVGAGPLLLLYVSLCPDSSVLTSPLDAVQNFSSERNPCNSSVPRDLRRPASLIGQEVVLVFFLLLLLVWFLNREFEVSYRLHYHGDVEADLHRTKIQSMRDQADWLLRNIIPYHVAEQLKVSQTYSKNHDSGGVIFASIVNFSEFYEENYEGGKECYRVLNELIGDFDELLSKPDYSSIEKIKTIGATYMAASGLNTAQAQDGSHPQEHLQILFEFAKEMMRVVDDFNNNMLWFNFKLRVGFNHGPLTAGVIGTTKLLYDIWGDTVNIASRMDTTGVECRIQVSEESYRVLSKMGYDFDYRGTVNVKGKGQMKTYLYPKCTDHRVIPQHQLSISPDIRVQVDGSIGRSPTDEIANLVPSVQYVDKTSLGSDSSTQAKDAHLSPKRPWKEPVKAEERGRFGKAIEKDDCDETGIEEANELTKLNVSKSV", "length": 1353 }, "evidence": [ { "id": "F1NP57", "url": "https://omabrowser.org/oma/group/F1NP57/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P51830-1", "protein_name": "Adenylate cyclase type 9", "gene_name": "Adcy9", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASSPHQQLLHHHSTEVSCDSSGDSNSVRVKINPKQLSSNTHPKHCKYSISSSCSSSGDSGGLPRRVGGGGRLRRQKKLPQLFERASSRWWDPKFDSMNLEEACLERCFPQTQRRFRYALFYVGFACLLWSIYFAVHMKSKVIVMVVPALCFLVVCVGFFLFTFTKLYARHYAWTSLALTLLVFALTLAAQFQVWTPLSGRVDSSNHTLTATPADTCLSQVGSFSICIEVLLLLYTVMQLPLYLSLFLGVVYSVLFETFGYHFRNEDCYPSPGPGALHWELLSRALLHVCIHAIGIHLFVMSQVRSRSTFLKVGQSIMHGKDLEVEKALKERMIHSVMPRIIADDLMKQGDEESENSVKRHATSSPKNRKKKSSIQKAPIAFRPFKMQQIEEVSILFADIVGFTKMSANKSAHALVGLLNDLFGRFDRLCEQTKCEKISTLGDCYYCVAGCPEPRADHAYCCIEMGLGMIKAIEQFCQEKKEMVNMRVGVHTGTVLCGILGMRRFKFDVWSNDVNLANLMEQLGVAGKVHISEATAKYLDDRYEMEDGRVIERLGQSVVADQLKGLKTYLISGQRAKESHCSCAEALLSGFEVIDDSRESSGPRGQGTASPGSVSDLAQTVKTFDNLKTCPSCGITFAPKSEAGAEGGTVQNGCQDEPKTSTKASGGPNSKTQNGLLSPPAEEKLTNSQTSLCEILQEKGRWAGVSLDQSALLPLRFKNIREKTDAHFVDVIKEDSLMKDYFFKPPINQFSLNFLDQELERSYRTSYQEEVIKNSPVKTFASATFSSLLDVFLSTTVFLILSITCFLKYGATATPPPPAALAVFGADLLLEVLSLIVSIRMVFFLEDVMTCTKWLLEWIAGWLPRHCIGAILVSLPALAVYSHITSEFETNIHVTMFTGSAVLVAVVHYCNFCQLSSWMRSSLATIVGAGLLLLLHISLCQDSSIVMSPLDSAQNFSAQRNPCNSSVLQDGRRPASLIGKELILTFFLLLLLVWFLNREFEVSYRLHYHGDVEADLHRTKIQSMRDQADWLLRNIIPYHVAEQLKVSQTYSKNHDSGGVIFASIVNFSEFYEENYEGGKECYRVLNELIGDFDELLSKPDYNSIEKIKTIGATYMAASGLNTAQCQEGGHPQEHLRILFEFAKEMMRVVDDFNNNMLWFNFKLRVGFNHGPLTAGVIGTTKLLYDIWGDTVNIASRMDTTGVECRIQVSEESYRVLSKMGYDFDYRGTVNVKGKGQMKTYLYPKCTDNGVVPQHQLSISPDIRVQVDGSIGRSPTDEIANLVPSVQYSDKASLGSDDSTQAKEARLSSKRSWREPVKAEERFPFGKAIEKDSCEDIGVEEASELSKLNVSKSV", "length": 1353 }, "evidence": [ { "id": "F1NP57", "url": "https://omabrowser.org/oma/group/F1NP57/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "adenylate cyclase activity", "id": "GO:0004016", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004016", "evidence": [ { "database": "UniProtKB", "id": "F1NP57", "url": "https://www.uniprot.org/uniprotkb/F1NP57" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "F1NP57", "url": "https://www.uniprot.org/uniprotkb/F1NP57" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "F1NP57", "url": "https://www.uniprot.org/uniprotkb/F1NP57" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F1NP57", "url": "https://www.uniprot.org/uniprotkb/F1NP57" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "cAMP biosynthetic process", "id": "GO:0006171", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006171", "evidence": [ { "database": "UniProtKB", "id": "F1NP57", "url": "https://www.uniprot.org/uniprotkb/F1NP57" } ], "pmid": "" }, { "name": "adenylate cyclase-activating G protein-coupled receptor signaling pathway", "id": "GO:0007189", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007189", "evidence": [ { "database": "UniProtKB", "id": "F1NP57", "url": "https://www.uniprot.org/uniprotkb/F1NP57" } ], "pmid": "" }, { "name": "intracellular signal transduction", "id": "GO:0035556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035556", "evidence": [ { "database": "UniProtKB", "id": "F1NP57", "url": "https://www.uniprot.org/uniprotkb/F1NP57" } ], "pmid": "" }, { "name": "adenylate cyclase-activating adrenergic receptor signaling pathway", "id": "GO:0071880", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071880", "evidence": [ { "database": "UniProtKB", "id": "F1NP57", "url": "https://www.uniprot.org/uniprotkb/F1NP57" } ], "pmid": "" }, { "name": "adenylate cyclase-modulating G protein-coupled receptor signaling pathway", "id": "GO:0007188", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007188", "evidence": [ { "database": "UniProtKB", "id": "F1NP57", "url": "https://www.uniprot.org/uniprotkb/F1NP57" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1060, "end_pos": 1062, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1115, "end_pos": 1117, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1341, "end_pos": 1343, "annotation": "n_glycosylation_sequon" }, { "start_pos": 206, "end_pos": 208, "annotation": "n_glycosylation_sequon" }, { "start_pos": 409, "end_pos": 411, "annotation": "n_glycosylation_sequon" }, { "start_pos": 654, "end_pos": 656, "annotation": "n_glycosylation_sequon" }, { "start_pos": 949, "end_pos": 951, "annotation": "n_glycosylation_sequon" }, { "start_pos": 958, "end_pos": 960, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "15389", "name": "", "equation": "ATP = 3',5'-cyclic AMP + diphosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A1D5PNE8-1", "A0A8V0XY43-1", "A0A8V0Y1I5-1", "F1NP57-1", "A0A1D5P0J0-1", "A0A8V0ZXY7-1", "A0A8V0ZZF3-1", "E1BX91-1", "Q9DGG6-1" ], "evidence": [ { "id": "15389", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/15389" } ] }, { "id": "R-GGA-111930", "name": "Adenylate cyclase produces cAMP", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1NP57-1", "A0A1D5P0J0-1", "A0A8V0XY43-1", "A0A8V0Y1I5-1", "A0A8V0ZXY7-1", "A0A8V0ZZF3-1", "E1BX91-1", "A0A1D5PNE8-1" ], "evidence": [ { "id": "R-GGA-111930", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-111930" } ] }, { "id": "R-GGA-170666", "name": "Adenylate cyclase increases the GTPase activity of G alpha-olf", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1NP57-1", "A0A1D5P0J0-1", "A0A8V0XY43-1", "A0A8V0Y1I5-1", "A0A8V0ZXY7-1", "A0A8V0ZZF3-1", "E1BX91-1", "A0A1D5PNE8-1" ], "evidence": [ { "id": "R-GGA-170666", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-170666" } ] }, { "id": "R-GGA-170671", "name": "G alpha-olf:GTP binds to Gi alpha1:GTP:adenylate cyclase complex", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1NP57-1", "A0A1D5P0J0-1", "A0A8V0XY43-1", "A0A8V0Y1I5-1", "A0A8V0ZXY7-1", "A0A8V0ZZF3-1", "E1BX91-1", "A0A1D5PNE8-1" ], "evidence": [ { "id": "R-GGA-170671", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-170671" } ] }, { "id": "R-GGA-170672", "name": "Galpha-olf:GTP binds to adenylate cyclase and activates it", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1NP57-1", "A0A1D5P0J0-1", "A0A8V0XY43-1", "A0A8V0Y1I5-1", "A0A8V0ZXY7-1", "A0A8V0ZZF3-1", "E1BX91-1", "A0A1D5PNE8-1" ], "evidence": [ { "id": "R-GGA-170672", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-170672" } ] }, { "id": "R-GGA-170674", "name": "Dissociation of the Gi alpha:G olf complex", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1NP57-1", "A0A1D5P0J0-1", "A0A8V0XY43-1", "A0A8V0Y1I5-1", "A0A8V0ZXY7-1", "A0A8V0ZZF3-1", "E1BX91-1", "A0A1D5PNE8-1" ], "evidence": [ { "id": "R-GGA-170674", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-170674" } ] }, { "id": "R-GGA-170676", "name": "Adenylate cyclase converts ATP into cyclic AMP", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1NP57-1", "A0A1D5P0J0-1", "A0A8V0XY43-1", "A0A8V0Y1I5-1", "A0A8V0ZXY7-1", "A0A8V0ZZF3-1", "E1BX91-1", "A0A1D5PNE8-1" ], "evidence": [ { "id": "R-GGA-170676", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-170676" } ] }, { "id": "R-GGA-170677", "name": "The G alpha-olf:GDP:Adenylate cyclase complex dissociates", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1NP57-1", "A0A1D5P0J0-1", "A0A8V0XY43-1", "A0A8V0Y1I5-1", "A0A8V0ZXY7-1", "A0A8V0ZZF3-1", "E1BX91-1", "A0A1D5PNE8-1" ], "evidence": [ { "id": "R-GGA-170677", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-170677" } ] }, { "id": "R-GGA-170685", "name": "Adenylaye cyclase increases the GTPase activity of G alpha-olf", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1NP57-1", "A0A1D5P0J0-1", "A0A8V0XY43-1", "A0A8V0Y1I5-1", "A0A8V0ZXY7-1", "A0A8V0ZZF3-1", "E1BX91-1", "A0A1D5PNE8-1" ], "evidence": [ { "id": "R-GGA-170685", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-170685" } ] }, { "id": "R-GGA-170686", "name": "Adenylate cyclase increases the GTPase activity of Gi alpha", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1NP57-1", "A0A1D5P0J0-1", "A0A8V0XY43-1", "A0A8V0Y1I5-1", "A0A8V0ZXY7-1", "A0A8V0ZZF3-1", "E1BX91-1", "A0A1D5PNE8-1" ], "evidence": [ { "id": "R-GGA-170686", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-170686" } ] }, { "id": "R-GGA-392064", "name": "G alpha (z) inhibits adenylate cyclase", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1NP57-1", "A0A1D5P0J0-1", "A0A8V0XY43-1", "A0A8V0Y1I5-1", "A0A8V0ZXY7-1", "A0A8V0ZZF3-1", "E1BX91-1", "A0A1D5PNE8-1" ], "evidence": [ { "id": "R-GGA-392064", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-392064" } ] }, { "id": "R-GGA-5610727", "name": "GPR161 promotes cAMP production in a G alpha(s)-dependent manner", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1NP57-1", "A0A1D5P0J0-1", "A0A8V0XY43-1", "A0A8V0Y1I5-1", "A0A8V0ZXY7-1", "A0A8V0ZZF3-1", "E1BX91-1", "A0A1D5PNE8-1" ], "evidence": [ { "id": "R-GGA-5610727", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5610727" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A1D5P0J0", "gene_name": "ADCY5", "activity": [ { "ec_number": "4.6.1.1", "activity": "ATP = 3',5'-cyclic AMP + diphosphate.", "evidence": [ { "id": "A0A1D5P0J0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P0J0" } ] }, { "ec_number": "4.6.1.1", "activity": "", "evidence": [ { "id": "A0A1D5P0J0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P0J0" } ] } ] }, { "uniprot_ac": "A0A1D5PNE8", "gene_name": "ADCY8", "activity": [ { "ec_number": "4.6.1.1", "activity": "ATP = 3',5'-cyclic AMP + diphosphate.", "evidence": [ { "id": "A0A1D5PNE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PNE8" } ] }, { "ec_number": "4.6.1.1", "activity": "", "evidence": [ { "id": "A0A1D5PNE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PNE8" } ] } ] }, { "uniprot_ac": "A0A8V0XY43", "gene_name": "ADCY1", "activity": [ { "ec_number": "4.6.1.1", "activity": "ATP = 3',5'-cyclic AMP + diphosphate.", "evidence": [ { "id": "A0A8V0XY43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XY43" } ] }, { "ec_number": "4.6.1.1", "activity": "", "evidence": [ { "id": "A0A8V0XY43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XY43" } ] } ] }, { "uniprot_ac": "A0A8V0Y1I5", "gene_name": "ADCY3", "activity": [ { "ec_number": "4.6.1.1", "activity": "ATP = 3',5'-cyclic AMP + diphosphate.", "evidence": [ { "id": "A0A8V0Y1I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y1I5" } ] }, { "ec_number": "4.6.1.1", "activity": "", "evidence": [ { "id": "A0A8V0Y1I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y1I5" } ] } ] }, { "uniprot_ac": "A0A8V0ZXY7", "gene_name": "ADCY6", "activity": [ { "ec_number": "4.6.1.1", "activity": "ATP = 3',5'-cyclic AMP + diphosphate.", "evidence": [ { "id": "A0A8V0ZXY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXY7" } ] }, { "ec_number": "4.6.1.1", "activity": "", "evidence": [ { "id": "A0A8V0ZXY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXY7" } ] } ] }, { "uniprot_ac": "A0A8V0ZZF3", "gene_name": "ADCY7", "activity": [ { "ec_number": "4.6.1.1", "activity": "ATP = 3',5'-cyclic AMP + diphosphate.", "evidence": [ { "id": "A0A8V0ZZF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZF3" } ] }, { "ec_number": "4.6.1.1", "activity": "", "evidence": [ { "id": "A0A8V0ZZF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZF3" } ] } ] }, { "uniprot_ac": "E1BX91", "gene_name": "ADCY2", "activity": [ { "ec_number": "4.6.1.1", "activity": "ATP = 3',5'-cyclic AMP + diphosphate.", "evidence": [ { "id": "E1BX91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BX91" } ] }, { "ec_number": "4.6.1.1", "activity": "", "evidence": [ { "id": "E1BX91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BX91" } ] } ] }, { "uniprot_ac": "F1NP57", "gene_name": "ADCY9", "activity": [ { "ec_number": "4.6.1.1", "activity": "ATP = 3',5'-cyclic AMP + diphosphate.", "evidence": [ { "id": "F1NP57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NP57" } ] }, { "ec_number": "4.6.1.1", "activity": "", "evidence": [ { "id": "F1NP57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NP57" } ] } ] }, { "uniprot_ac": "Q9DGG6", "gene_name": "ADCY9", 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"uniprot_id": "F1NPJ5_CHICK", "mass": { "chemical_mass": 76863.0, "monoisotopic_mass": 76863.0 }, "refseq": { "ac": "XP_416420", "name": "solute carrier organic anion transporter family member 1C1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_416420" }, "gene_names": [ { "name": "SLCO1B1", "type": "recommended", "evidence": [ { "id": "F1NPJ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NPJ5" } ] }, { "name": "SLCO1B1", "type": "synonym", "evidence": [ { "id": "XP_416420", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_416420" } ] } ], "protein_names": [ { "name": "Solute carrier organic anion transporter family member", "type": "recommended", "evidence": [ { "id": "F1NPJ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NPJ5/entry#names_and_taxonomy" } ] }, { "name": "solute carrier organic anion transporter family member 1C1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_416420", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_416420" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process On Jun 19, 2013 this sequence version replaced XP_416420.3. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_416420", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_416420" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NPJ5", "url": "https://www.uniprot.org/uniprotkb/F1NPJ5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SLCO1B1", "url": "https://www.uniprot.org/uniprotkb/F1NPJ5", "locus": {} } ], "crossref": [ { "id": "F1NPJ5", "url": "https://alphafold.ebi.ac.uk/entry/F1NPJ5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000019276", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000019276", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "418189", "url": "https://www.ncbi.nlm.nih.gov/gene/418189", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002350", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002350", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004156", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004156", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020846", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020846", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036058", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036058", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036259", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036259", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:418189", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418189", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "VINAGCE", "url": 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"categories": [ "Protein" ] }, { "id": "A0A8V0YCI6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCI6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YCI6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCI6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NPJ5", "url": "https://www.uniprot.org/uniprotkb/F1NPJ5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NPJ5-1", "url": "https://www.uniprot.org/uniprotkb/F1NPJ5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDKIITTGKLKDKPPFRDSSSAVVPAKVMCHNCSKLKIFLGALAFSFFAKGFSGSYMKSMSSQIERRFEISSSIFGIIDGSFELGNLMVMVLVSYLGPRVHRPKVIAVGCLIMSLGAFLSVMPQFLMGRYNYERIAVTVDNSSTSVSACSPASSVGHSVSDATETPSTMKNSGCEKTSNSYLWLFVLMGNLLRGIGEAPVMPLGVSYIDDFSKEENSAFYIGLVRSSGMFGPTLGFLLGSFCASLWVDIGVVDIDAININPKDTRWVGAWWLGLLICGAVNFIASLPFFFLPYSLIKEGEDENPKKISHLPVQGDHCKTDPPAQPQLKFSEAVKDFLPTLKKLFGNPVFLVYVFLTILQYNSLVGLITYETKFMEQQFNVSVAKAIFLVGVILLPITILGMFLGGYLIKKFKLHITGMAKFACISFIVAYLLNLLYFMCNCEVLQLAGLTVPYSGFKQLSSPKNSFMSSCNADCSCKVDQWDPVCGDNGITYMTACFAGCKSSTGMGKNMVFHNCSCVEGQEHGHGNASAVLGQCQRESCTKAFPYFLALQTACAFILALGGTPTYMIMFRSVSPDLKSFAVGIETLGGRILGGLPAPIYFGALIDETCLKWGTKSCGGSGSCRIYDTKAFRNVYLGLIAGLRAGCCVLYLVLCVLIMRRFKTDDKDTTDIKNAEETINKESVTVNKKEALPGAKTSEESEETCM", "length": 705, "header": "tr|F1NPJ5-1|F1NPJ5_CHICK Isoform 1 of Solute carrier organic anion transporter family member OS=Gallus gallus OX=9031 GN=SLCO1B1 PE=3 SV=3 CANONICAL=F1NPJ5-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YCI6-1", "url": "https://www.uniprot.org/uniprotkb/F1NPJ5/entry#A0A8V0YCI6-1", "sequence": { "sequence": "MDKIITTGKLKDKPPFRDSSSAVVPAKVMCHNCSKLKIFLGALAFSFFAKGFSGSYMKSMSSQIERRFEISSSIFGIIDGSFELGNLMVMVLVSYLGPRVHRPKVIAVGCLIMSLGAFLSVMPQFLMGRYNYERIAVTVDNSSTSVSACSPASSVGHSVSDATETPSTMKNSGCEKTSNSYLWLFVLMGNLLRGIGEAPVMPLGVSYIDDFSKEENSAFYIGLVRSSGMFGPTLGFLLGSFCASLWVDIGVVDIDFLPTLKKLFGNPVFLVYVFLTILQYNSLVGLITYETKFMEQQFNVSVAKAIFLVGVILLPITILGMFLGGYLIKKFKLHITGMAKFACISFIVAYLLNLLYFMCNCEVLQLAGLTVPYSGFKQLSSPKNSFMSSCNADCSCKVDQWDPVCGDNGITYMTACFAGCKSSTGMGKNMVFHNCSCVEGQEHGHGNASAVLGQCQRESCTKAFPYFLALQTACAFILALGGTPTYMIMFRSVSPDLKSFAVGIETLGGRILGGLPAPIYFGALIDETCLKWGTKSCGGSGSCRIYDTKAFRNVYLGLIAGLRAGCCVLYLVLCVLIMRRFKTDDKDTTDIKNAEETINKESVTVNKKEALPGAKTSEESEETCM", "length": 625, "header": "tr|A0A8V0YCI6-1|A0A8V0YCI6_CHICK Computationally mapped isoform of Solute carrier organic anion transporter family member OS=Gallus gallus OX=9031 GN=SLCO1B1 PE=3 SV=1 CANONICAL=F1NPJ5-1" }, "locus": { "chromosome": "1", "start_pos": 65272605, "end_pos": 65253473, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028242.1", "url": "https://www.ensembl.org/id/ENSGALT00010028242.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016180.1", "url": "https://www.ensembl.org/id/ENSGALP00010016180.1" } ] } }, { "isoform_ac": "F1NPJ5-1", "url": "https://www.uniprot.org/uniprotkb/F1NPJ5/entry#F1NPJ5-1", "sequence": { "sequence": "MDKIITTGKLKDKPPFRDSSSAVVPAKVMCHNCSKLKIFLGALAFSFFAKGFSGSYMKSMSSQIERRFEISSSIFGIIDGSFELGNLMVMVLVSYLGPRVHRPKVIAVGCLIMSLGAFLSVMPQFLMGRYNYERIAVTVDNSSTSVSACSPASSVGHSVSDATETPSTMKNSGCEKTSNSYLWLFVLMGNLLRGIGEAPVMPLGVSYIDDFSKEENSAFYIGLVRSSGMFGPTLGFLLGSFCASLWVDIGVVDIDAININPKDTRWVGAWWLGLLICGAVNFIASLPFFFLPYSLIKEGEDENPKKISHLPVQGDHCKTDPPAQPQLKFSEAVKDFLPTLKKLFGNPVFLVYVFLTILQYNSLVGLITYETKFMEQQFNVSVAKAIFLVGVILLPITILGMFLGGYLIKKFKLHITGMAKFACISFIVAYLLNLLYFMCNCEVLQLAGLTVPYSGFKQLSSPKNSFMSSCNADCSCKVDQWDPVCGDNGITYMTACFAGCKSSTGMGKNMVFHNCSCVEGQEHGHGNASAVLGQCQRESCTKAFPYFLALQTACAFILALGGTPTYMIMFRSVSPDLKSFAVGIETLGGRILGGLPAPIYFGALIDETCLKWGTKSCGGSGSCRIYDTKAFRNVYLGLIAGLRAGCCVLYLVLCVLIMRRFKTDDKDTTDIKNAEETINKESVTVNKKEALPGAKTSEESEETCM", "length": 705, "header": "tr|F1NPJ5-1|F1NPJ5_CHICK Isoform 1 of Solute carrier organic anion transporter family member OS=Gallus gallus OX=9031 GN=SLCO1B1 PE=3 SV=3 CANONICAL=F1NPJ5-1" }, "locus": { "chromosome": "1", "start_pos": 65272605, "end_pos": 65253473, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028254.1", "url": "https://www.ensembl.org/id/ENSGALT00010028254.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016186.1", "url": "https://www.ensembl.org/id/ENSGALP00010016186.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:418189", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418189", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "F1NPJ5", "url": "https://www.uniprot.org/uniprotkb/F1NPJ5" } ], "pmid": "" }, { "name": "basolateral plasma membrane", "id": "GO:0016323", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016323", "evidence": [ { "database": "UniProtKB", "id": "F1NPJ5", "url": "https://www.uniprot.org/uniprotkb/F1NPJ5" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F1NPJ5", "url": "https://www.uniprot.org/uniprotkb/F1NPJ5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "monoatomic ion transport", "id": "GO:0006811", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006811", "evidence": [ { "database": "UniProtKB", "id": "F1NPJ5", "url": "https://www.uniprot.org/uniprotkb/F1NPJ5" } ], "pmid": "" }, { "name": "bile acid and bile salt transport", "id": "GO:0015721", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015721", "evidence": [ { "database": "UniProtKB", "id": "F1NPJ5", "url": "https://www.uniprot.org/uniprotkb/F1NPJ5" } ], "pmid": "" }, { "name": "sodium-independent organic anion transport", "id": "GO:0043252", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043252", "evidence": [ { "database": "UniProtKB", "id": "F1NPJ5", "url": "https://www.uniprot.org/uniprotkb/F1NPJ5" } ], "pmid": "" }, { "name": "transmembrane transport", "id": "GO:0055085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055085", "evidence": [ { "database": "UniProtKB", "id": "F1NPJ5", "url": "https://www.uniprot.org/uniprotkb/F1NPJ5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "bile acid transmembrane transporter activity", "id": "GO:0015125", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015125", "evidence": [ { "database": "UniProtKB", "id": "F1NPJ5", "url": "https://www.uniprot.org/uniprotkb/F1NPJ5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 141, "end_pos": 143, "annotation": "n_glycosylation_sequon" }, { "start_pos": 32, "end_pos": 34, "annotation": "n_glycosylation_sequon" }, { "start_pos": 379, "end_pos": 381, "annotation": "n_glycosylation_sequon" }, { "start_pos": 514, "end_pos": 516, "annotation": "n_glycosylation_sequon" }, { "start_pos": 527, "end_pos": 529, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1NPJ5-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 705, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1NPJ5-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1NPJ5" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1NPJ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NPJ5" }, { "id": "PS51465", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51465" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Kazal-like", "eco_id": "ECO_0000259", "start_pos": 464, "end_pos": 519, "start_aa": "Asn", "end_aa": "Glu", "glycosite_overlap": "" }, { "evidence": [ { "id": "F1NPJ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NPJ5" }, { "id": "PS50850", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50850" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Major facilitator superfamily (MFS) profile", "eco_id": "ECO_0000259", "start_pos": 39, "end_pos": 662, "start_aa": "Phe", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 141, "end_pos": 143 }, { "start_pos": 32, "end_pos": 34 }, { "start_pos": 379, "end_pos": 381 }, { "start_pos": 514, "end_pos": 516 }, { "start_pos": 527, "end_pos": 529 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { 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"total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1NPS0-1", "uniprot_ac": "F1NPS0", "uniprot_id": "F1NPS0_CHICK", "mass": { "chemical_mass": 154144.0, "monoisotopic_mass": 154144.0 }, "refseq": { "ac": "XP_004937254", "name": "nuclear pore complex protein Nup155", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004937254" }, "gene_names": [ { "name": "NUP155", "type": "recommended", "evidence": [ { "id": "F1NPS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NPS0" } ] }, { "name": "NUP155", "type": "synonym", "evidence": [ { "id": "XP_004937254", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004937254" } ] } ], "protein_names": [ { "name": "Nuclear pore complex protein Nup155", "type": "recommended", "evidence": [ { "id": "F1NPS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NPS0/entry#names_and_taxonomy" } ] }, { "name": "155 kDa nucleoporin", "type": "synonym", "evidence": [ { "id": "F1NPS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NPS0/entry#names_and_taxonomy" } ] }, { "name": "Nucleoporin Nup155", "type": "synonym", "evidence": [ { "id": "F1NPS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NPS0/entry#names_and_taxonomy" } ] }, { "name": "nuclear pore complex protein Nup155", "type": "synonym", "evidence": [ { "id": "XP_004937254", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004937254" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052572.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004937254", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004937254" } ] }, { "annotation": "Essential component of nuclear pore complex. Could be essessential for embryogenesis. Nucleoporins may be involved both in binding and translocating proteins during nucleocytoplasmic transport.", "evidence": [ { "database": "UniProtKB", "id": "F1NPS0", "url": "https://www.uniprot.org/uniprotkb/F1NPS0#function" }, { "database": "UniProtKB", "id": "ARBA00058219", "url": "https://www.uniprot.org/uniprotkb/ARBA00058219#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NPS0", "url": "https://www.uniprot.org/uniprotkb/F1NPS0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "NUP155", "url": "https://www.uniprot.org/uniprotkb/F1NPS0", "locus": { "chromosome": "Z", "start_pos": 12085107, "end_pos": 12116466, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012803", "url": 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"database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-3301854", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3301854", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-4085377", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-4085377", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-4551638", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-4551638", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-4615885", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-4615885", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9615933", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9615933", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_004937254", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004937254", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1NPS0", "url": "https://www.uniprot.org/uniprotkb/F1NPS0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NPS0-1", "url": "https://www.uniprot.org/uniprotkb/F1NPS0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPAAMSPTVPAGHEALEIAGRIIDRQIQDDRCYPDLSELLAVPAPGSPTVSGMTDMDYPLQGPGLLSIPNLPEISSVRRVPLPPELVEQFGHMQCNCMMGVFPEISRAWLTIDSDIFMWNYEDGGDLAYFDGLSETILAVGLVKPKGGIFQPHVRHLLVLATPVDIVILGLSCANTQAGTGPLNDSLSGGMQLLPDPLYSLPTDNTYISAITSTDNGRIFLAGKDGCLYEVAYQAEAGWFSQRCRKINHSKSALSFLIPSLLQFTFSEDDPVVQIAIDNSRNILYTRSEKGVLQVYDLGQDGQGMARVTSLSQNAIVSAAGSIARTIDRSVFKPIVQIAVIENSESIDCQLLAVTHAGVRLYFSTSQFKHPAARPSMLTLVHVRLPPGFSASSNVEKPSKVHRALYCKGVLLMAASENEDNDILWCINHDSFPFQKPMMETQMTTRVDGHSWALSAIDEFKVQKIVTPLNKDVIPITDSPIVVQQHMLPPKRFVLLSAQGSFMFHKLRPVDQLRHLLVSNTGGDGEEIERFFKLHQEDQACATCLILACSNAACDTEVSAWATRAFFRYGGEAQMRFPSALPPPSNVGPILGSPIPPVSPLTVDSPYPSPSLLTGPGPGLQSTTVSTPIFPPGNSVSHPGTSISSGIMGPEIVFSGRHNGICIYFARIIGNIWDGSIVVEKIFKSGNREVVAIESSVPSHVLECVLQELKGLQEFLDRNSQFATVGALGNPSFSTPANLQQRLLGFMRPDGGSSQQVQQELQRKYHAEAQLTEKNSLQGIQQLVRKTCQALALWKLLCEHQFSVVVGELQKELQEHLKMTAFKDLVIRDKELTGALIASLINCYIRDNAAVDGISAHLQDICPLLYSTDDAVCSKANELLQRSRQAQNKLEKEKMLRESLKEYQKISNQVDLANVCAQYRQVRFYEGVVELSLTAAEKKDPQGLGLHFYKNGEPEEDAVGLQAFQERLNSYKCITDTLQELVNQSKAAPQSPSVPKKPGPPVLSSDPNMLSNEEAGHHFEQMLKLAQRSTDELFSIALYNWLIQVDLADKLLQVTAPFLEPYLVRMTKIDQNKVRYMDLLWRYFEKNRNFSNAARVLAKLADLHSTEISLQQRLEYIARAILSAKSSTAISSIAADGEFLHELEEKMDVARIQLQIQETLQRQYSHHSSVQDAVSQLDAELMDITKLYGEFADPFKLSECKLAIIHCAGHSDPILVQTLWQEIIEKELSDSVSLSPADRMQALSLKMALLGKIYAGTPRYFPLDFLVQFLEQQVCALNWDVGFVTYTMQEIGVPLPRLLEVYDQLFKARDPYWNRMKKPLHLLECIHVLLSGYVQDPSRVLMRRRFTNVCLDAVSCYLVELQSMSPTLMVQTTIGNFKSLQAKLERLH", "length": 1388, "header": "tr|F1NPS0-1|F1NPS0_CHICK Isoform 1 of Nuclear pore complex protein Nup155 OS=Gallus gallus OX=9031 GN=NUP155 PE=1 SV=3 CANONICAL=F1NPS0-1" }, "isoforms": [ { "isoform_ac": "F1NPS0-1", "url": "https://www.uniprot.org/uniprotkb/F1NPS0/entry#F1NPS0-1", "sequence": { "sequence": "MPAAMSPTVPAGHEALEIAGRIIDRQIQDDRCYPDLSELLAVPAPGSPTVSGMTDMDYPLQGPGLLSIPNLPEISSVRRVPLPPELVEQFGHMQCNCMMGVFPEISRAWLTIDSDIFMWNYEDGGDLAYFDGLSETILAVGLVKPKGGIFQPHVRHLLVLATPVDIVILGLSCANTQAGTGPLNDSLSGGMQLLPDPLYSLPTDNTYISAITSTDNGRIFLAGKDGCLYEVAYQAEAGWFSQRCRKINHSKSALSFLIPSLLQFTFSEDDPVVQIAIDNSRNILYTRSEKGVLQVYDLGQDGQGMARVTSLSQNAIVSAAGSIARTIDRSVFKPIVQIAVIENSESIDCQLLAVTHAGVRLYFSTSQFKHPAARPSMLTLVHVRLPPGFSASSNVEKPSKVHRALYCKGVLLMAASENEDNDILWCINHDSFPFQKPMMETQMTTRVDGHSWALSAIDEFKVQKIVTPLNKDVIPITDSPIVVQQHMLPPKRFVLLSAQGSFMFHKLRPVDQLRHLLVSNTGGDGEEIERFFKLHQEDQACATCLILACSNAACDTEVSAWATRAFFRYGGEAQMRFPSALPPPSNVGPILGSPIPPVSPLTVDSPYPSPSLLTGPGPGLQSTTVSTPIFPPGNSVSHPGTSISSGIMGPEIVFSGRHNGICIYFARIIGNIWDGSIVVEKIFKSGNREVVAIESSVPSHVLECVLQELKGLQEFLDRNSQFATVGALGNPSFSTPANLQQRLLGFMRPDGGSSQQVQQELQRKYHAEAQLTEKNSLQGIQQLVRKTCQALALWKLLCEHQFSVVVGELQKELQEHLKMTAFKDLVIRDKELTGALIASLINCYIRDNAAVDGISAHLQDICPLLYSTDDAVCSKANELLQRSRQAQNKLEKEKMLRESLKEYQKISNQVDLANVCAQYRQVRFYEGVVELSLTAAEKKDPQGLGLHFYKNGEPEEDAVGLQAFQERLNSYKCITDTLQELVNQSKAAPQSPSVPKKPGPPVLSSDPNMLSNEEAGHHFEQMLKLAQRSTDELFSIALYNWLIQVDLADKLLQVTAPFLEPYLVRMTKIDQNKVRYMDLLWRYFEKNRNFSNAARVLAKLADLHSTEISLQQRLEYIARAILSAKSSTAISSIAADGEFLHELEEKMDVARIQLQIQETLQRQYSHHSSVQDAVSQLDAELMDITKLYGEFADPFKLSECKLAIIHCAGHSDPILVQTLWQEIIEKELSDSVSLSPADRMQALSLKMALLGKIYAGTPRYFPLDFLVQFLEQQVCALNWDVGFVTYTMQEIGVPLPRLLEVYDQLFKARDPYWNRMKKPLHLLECIHVLLSGYVQDPSRVLMRRRFTNVCLDAVSCYLVELQSMSPTLMVQTTIGNFKSLQAKLERLH", "length": 1388, "header": "tr|F1NPS0-1|F1NPS0_CHICK Isoform 1 of Nuclear pore complex protein Nup155 OS=Gallus gallus OX=9031 GN=NUP155 PE=1 SV=3 CANONICAL=F1NPS0-1" }, "locus": { "chromosome": "Z", "start_pos": 12116270, "end_pos": 12085413, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030719.1", "url": "https://www.ensembl.org/id/ENSGALT00010030719.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017814.1", "url": "https://www.ensembl.org/id/ENSGALP00010017814.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 735, "start_aa": "Thr", "end_pos": 735, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr735", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:427443", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427443", "resource": "KEGG Pathway" }, { "id": "R-GGA-159227", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-159227", "resource": "Reactome", "description": "Transport of the SLBP independent Mature mRNA" }, { "id": "R-GGA-159230", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-159230", "resource": "Reactome", "description": "Transport of the SLBP Dependant Mature mRNA" }, { "id": "R-GGA-159231", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-159231", "resource": "Reactome", "description": "Transport of Mature mRNA Derived from an Intronless Transcript" }, { "id": "R-GGA-159236", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-159236", "resource": "Reactome", "description": "Transport of Mature mRNA derived from an Intron-Containing Transcript" }, { "id": "R-GGA-1855170", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1855170", "resource": "Reactome", "description": "IPs transport between nucleus and cytosol" }, { "id": "R-GGA-1855196", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1855196", "resource": "Reactome", "description": "IP3 and IP4 transport between cytosol and nucleus" }, { "id": "R-GGA-1855229", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1855229", "resource": "Reactome", "description": "IP6 and IP7 transport between cytosol and nucleus" }, { "id": "R-GGA-191859", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-191859", "resource": "Reactome", "description": "snRNP Assembly" }, { "id": "R-GGA-3108214", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3108214", "resource": "Reactome", "description": "SUMOylation of DNA damage response and repair proteins" }, { "id": "R-GGA-3232142", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3232142", "resource": "Reactome", "description": "SUMOylation of ubiquitinylation proteins" }, { "id": "R-GGA-3301854", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3301854", "resource": "Reactome", "description": "Nuclear Pore Complex (NPC) Disassembly" }, { "id": "R-GGA-4085377", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-4085377", "resource": "Reactome", "description": "SUMOylation of SUMOylation proteins" }, { "id": "R-GGA-4551638", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-4551638", "resource": "Reactome", "description": "SUMOylation of chromatin organization proteins" }, { "id": "R-GGA-4615885", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-4615885", "resource": "Reactome", "description": "SUMOylation of DNA replication proteins" }, { "id": "R-GGA-9615933", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9615933", "resource": "Reactome", "description": "Postmitotic nuclear pore complex (NPC) reformation" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3Q1M9F3-1", "protein_name": "Nuclear pore complex protein Nup155", "gene_name": "NUP155", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MQASNSPPDEPEVRHAVAPGRSFGARALSFGLELASWVLSYFSLLFDFLRSLLSSILDMPSSLLGSAMPASTSAAALQEALENAGRLIDRQLQEDRMYPDLSELLMVSAPNNPTVSGMSDMDYPLQGPGLLSVPNLPDISSIRRVPLPPELVEQFGHMQCNCMMGVFPPISRAWLTIDSDIFMWNYEDGGDLAYFDGLSETILAVGLVKPKPGIFQPHVRHLLVLATPVDIVILGLSYTNLQTGSGVLNDSMCGGMQLLPDPLYSLPTDNTYLLTITSTDNGRIFLAGKDGCLYEVAYQAEAGWFSQRCRKINHSKSPLSFLVPSLLQFTFSEDDPIVQIAVDNSRNILYTRSEKGVIQVYDLGHDGQGMNRVASVSQNSIVSAAGNIARTIDRSVFKPIVQIAVIENSESLDCQLLAVTHAGVRLYFSTCPFRQPLARPNTLTLVHVRLPPGFSASSTVEKPSKVHKALYSKGILLMAASENEDNDILWCVNHDTFPFQKPMMETQMTTRVDGHSWALSAIDELKVDKIITPLNKDHIPITDSPVVVQQHMLPPKKFVLLSAQGSLMFHKLRPVDQLRHLLVSNVGGDGEEIERFFKLHQEDQACATCLILACSTAACDREVSAWATRAFFRYGGEAQMRFPTTLPTPSNVGPILGSPVYSSSPVPSGTLYPNPSFLGTPSQGVHPPAVSTPVCALGSPATQATSMSCMAGPEIVYSGKHNGICIYFSRIMGNIWDASLVVERVFKSGNREITAIESSVPSQLLESVLLELKGLQEFLDRNSQFTGGPLGNPNTAAKVQQRLIGFMRPENGNTQQMQQELQRKLHEAQLSEKISLQAIQQLVRKSYQALALWKLLCEHQFTVIVGELQKEFQEQLKITTFKDLVIRDKELTGALIASLINCYIRDNAAVDGISLHLQDICPLLYSTDDAICSKANELLQHSRQVQNKIEKERMLRESLKEYQKISNQVDLSSVCAQYRQVRFYEGVVELSLTAAEKKDPQGLGLHFYKHGEPEEDIVGLQAFQERLNSYKCITDTLQELVNQSKAAPQSPSVPKKPGPPVLSSDPNMLSNEEAGHHFEQMLKLSQRSKDELFSIALYNWLIQADLADKLLQIASPFLEPHLVRMAKVDQNKVRYMDLLWRYYEKNRSFSSAARVLSKLADMHSTEISLQQRLEYIARAILSAKSSTAISSTAADGEFLHELEEKMEVARIQLQIQETLQRQYSHHSSVQDAISQLDSELMDITKLYGEFADPFKLAECKLAIIHCAGYSDPILVQTLWQDIIEKELNESVTLSSPDRMHALSLKIVLLGKIYAGTPRFFPLDFIVQFLEQQVCTLNWDVGFVIQTMNEIGVPLPRLLEVYDHLFKSRDPFWNRMKKPLHLLDCIHVLLTRYVENPSQVLNCERRRFTNLCLDAVCGYLVELQSMSSSAAVQAITGNFKSLQAKLERLH", "length": 1449 }, "evidence": [ { "id": "F1NPS0", "url": "https://omabrowser.org/oma/group/F1NPS0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F4HXV6-1", "protein_name": "Nuclear pore complex protein NUP155", "gene_name": "NUP155", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSQDDEIVMRDVTSAGICIGDRIGREAASQLDLEEALEASRYASHPYSTHPREWPPLIEVGETWELPSVLIERYNTAGGEGTALCGIFPEIRRAWASVDNSLFLWRFDKRDGQCPEYSGEEQAICAVGLAKCRPGVFVEAIQYLLVLATPVELVLVGVCCTEGPDGRDPYAEISVQPLPDYTISSDGVTMTCVTCTNKGRIFMAGRDGHIYELLYTTGSGWNKRCRKVCLTAGVGSMISRWVVPNVFKFGAVDPVVEMVVDNERQILYARTEEMKLQAYVSGPNGEGPLKKVAEERNLLNQKDLSQGNRQSAVAGRSNKPSIVSISPLSMLESKWLHLVAALSDGRRMYLSTSSSGSGSTISFSGFNNHRQTPNCLKVVSTRPSPPLGVGVGLGFGAASVAGRTQNDDLSMKIETAYYSVGTLVLSDSSPPAMSSLLVVSRDSSVHSQAGSSSGPSSRSSRALREVVSSLPIEGRMLFVADVLPSPDTAATIQSLYSELEYCGVEVSGESYEKACGKLWARSDLSTQHILPRRKIVVFTTMGMMELVFNRPVDILRRLLESNSPRSLLEDFFTRFGVGEAAAMCLMLAARIINFEDLISNIVADKAAEAFEDPRIVGMPQFDGSSGLSNTRTATGGFSMGQVVQEAEPIFSGAHEGLCLCTSRLLFPLWELPVMSKKTSSDTMSEDGVVICRLSTSAMHVLESKIRSLEKFLRSRRNQRRGLYGCVAGLGDVTGSILYGTGSELGATERNMVRNLFGAYSNGGESANKRQRLPYSPAELAATEVRAMECIRQLLLRSAEALFLLQLLSQHHVARLVQELDANLKQALVQLTFHQLVCSEEGDQIATRLISAVMEYYTGSDGRGTVDDISPRLREGCPSYFKESDYKFYLAVERLERAALTSDAEEKENVAREAFSFLSKVPGSADLQTVCKRFEDLRFYEAVVCLPLQKAQALDPAGDAFNDQLDASIREHALAQRKQCYEIIANALRSLASPLASPTLDEASRSQYICQIVHLGVQSTDRAFREYLYKAMIELHLENELLEYGGPDLVPFLQNAGSHSESQVGAVSTGSSPLGHSGTQISSDQAKYFDLLAKYYVSKRQHVLAAHVFLRLAERRAISLGDSPTLERRRDDLSQAVLQAKNASNSDGLVGSAQGVSDSGLLDLLEGKLAVLQFQIKIRDKLEAIASNFESSVAMQDSDQNGQVLDGDSSDDTNLANAANEMAMEVSSELKSVTQLYNEYAVPFELWEICLEMLYFANYSGDADSSIIRETWARLIDQALSQGGIREACAVLKRVGSHIYPGDGVVLPLDVLCLHLERAALERSERIENVRDEDIAKALLAACKGAAEPVLNAYDRLLSNAAVVPSPNLRIRLLRSVLVVLREWAMSVLSDRMGSSPTRSSLILGGSFALENKAALNQGARDKIANAANRYMTEVRRLALPPNKTDGVYAGFKELDESLLSPFSF", "length": 1464 }, "evidence": [ { "id": "F1NPS0", "url": "https://omabrowser.org/oma/group/F1NPS0/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "O75694-1", "protein_name": "Nuclear pore complex protein Nup155", "gene_name": "NUP155", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPSSLLGAAMPASTSAAALQEALENAGRLIDRQLQEDRMYPDLSELLMVSAPNNPTVSGMSDMDYPLQGPGLLSVPNLPEISSIRRVPLPPELVEQFGHMQCNCMMGVFPPISRAWLTIDSDIFMWNYEDGGDLAYFDGLSETILAVGLVKPKAGIFQPHVRHLLVLATPVDIVILGLSYANLQTGSGVLNDSLSGGMQLLPDPLYSLPTDNTYLLTITSTDNGRIFLAGKDGCLYEVAYQAEAGWFSQRCRKINHSKSSLSFLVPSLLQFTFSEDDPILQIAIDNSRNILYTRSEKGVIQVYDLGQDGQGMSRVASVSQNAIVSAAGNIARTIDRSVFKPIVQIAVIENSESLDCQLLAVTHAGVRLYFSTCPFRQPLARPNTLTLVHVRLPPGFSASSTVEKPSKVHRALYSKGILLMAASENEDNDILWCVNHDTFPFQKPMMETQMTAGVDGHSWALSAIDELKVDKIITPLNKDHIPITDSPVVVQQHMLPPKKFVLLSAQGSLMFHKLRPVDQLRHLLVSNVGGDGEEIERFFKLHQEDQACATCLILACSTAACDREVSAWATRAFFRYGGEAQMRFPTTLPPPSNVGPILGSPVYSSSPVPSGSPYPNPSFLGTPSHGIQPPAMSTPVCALGNPATQATNMSCVTGPEIVYSGKHNGICIYFSRIMGNIWDASLVVERIFKSGNREITAIESSVPCQLLESVLQELKGLQEFLDRNSQFAGGPLGNPNTTAKVQQRLIGFMRPENGNPQQMQQELQRKFHEAQLSEKISLQAIQQLVRKSYQALALWKLLCEHQFTIIVAELQKELQEQLKITTFKDLVIRDKELTGALIASLINCYIRDNAAVDGISLHLQDICPLLYSTDDAICSKANELLQRSRQVQNKTEKERMLRESLKEYQKISNQVDLSNVCAQYRQVRFYEGVVELSLTAAEKKDPQGLGLHFYKHGEPEEDIVGLQAFQERLNSYKCITDTLQELVNQSKAAPQSPSVPKKPGPPVLSSDPNMLSNEEAGHHFEQMLKLSQRSKDELFSIALYNWLIQVDLADKLLQVASPFLEPHLVRMAKVDQNRVRYMDLLWRYYEKNRSFSNAARVLSRLADMHSTEISLQQRLEYIARAILSAKSSTAISSIAADGEFLHELEEKMEVARIQLQIQETLQRQYSHHSSVQDAVSQLDSELMDITKLYGEFADPFKLAECKLAIIHCAGYSDPILVQTLWQDIIEKELSDSVTLSSSDRMHALSLKIVLLGKIYAGTPRFFPLDFIVQFLEQQVCTLNWDVGFVIQTMNEIGVPLPRLLEVYDQLFKSRDPFWNRMKKPLHLLDCIHVLLIRYVENPSQVLNCERRRFTNLCLDAVCGYLVELQSMSSSVAVQAITGNFKSLQAKLERLH", "length": 1391 }, "evidence": [ { "id": "F1NPS0", "url": "https://omabrowser.org/oma/group/F1NPS0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P38181-1", "protein_name": "Nucleoporin NUP170", "gene_name": "NUP170", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MFQSFFHNNGPAAAGETFSDSRSYPLTNHQEVPRNGLNELASSATKAQQQPTHILNSYPITGSNPLMRASAMGATSGSINPNMSNMNEHIRVSGMGTSKPLDLAGKYIDHLQHKDSNTPVLDERSYYNSGVDYNFSREKNGLGAFTPFEKQDVFNIPDEILHEFSTSQTKTDMGIFPELNRCWITIDNKLILWNINNDNEYQVVDDMKHTIQKVALVRPKPNTFVPAVKHLLLISTTMELFMFAISLDKATNELSVFNTHLSVPVQGIDVIDIVSHERSGRIFFAGQASGLNIWELHYSGSDDWFNSKCSKVCLTKSALLSLLPTNMLSQIPGVDFIQALFEDNSNGNGGFSQETITQLTIDQQRGIIYSLSSKSTIRAYVITEKSLEGPMSIEPAYISRIIGTTTARAAPILGPKYLKIVKISSVAPEENNNLFLVALTVGGVRLYFNGSMGRFNIEALRLESIKFPPSSVTPEVIQQELLHQQQEQAKRSFPFFSNLMSSEPVLLKFQKKSSVLLETTKASTIISPGIFFSAVIKSSQQTHQQEKKENSSVTGTTATAGSKTVKQQPVTLQHKLFVSVPDYGILKTHGKYVENATFLETAGPVQQIIPLSGLFNATTKPQGFANEFATQYTSETLRVAVLTSTSIEIYKYRTPDEIFEDLIDNPLPFVLNYGAAEACSTALFVTCKSNKSEKLRSNALTFLTMGIPGVVDIKPVYNRYSVSTVSSLLSKPTLSTATTNLQQSITGFSKPSPANKEDFDLDDVILSPRFYGIALLITRLLRDIWGRHVFMTFTDNRVTSHAFISSSDPITPSINNLKSDEISQNRNIISKVSISKDCIEYYLSSINILNEFFITYGDSISQISAPYVLANNSNGRVIDKTEEVANQAESIAINAMIKMVQSIKEGLSFLNVLYEESEVEGFDNQYLGFKDIISFVSLDVQKDLVKLDFKDLFAPNDKTKSLIREILLSIINRNITKGASIEYTATALQERCGSFCSASDILGFRAIEHLRRAKEIGLRNYDSLNYHLKNATALLEQIVDDLSIEKLKEAVSMMLSVNYYPKSIEFLLNIANSMDKGKLACQYVANGFLENDDRKQYYDKRILVYDLVFDTLIKVDELAEKKQSSKTQNQISISNDDEVKLRQKSYEAALKYNDRLFHYHMYDWLVSQNREEKLLDIETPFILPYLMEKAGSSLKISNILWVYYSRRSKFFESAEILYRLATSNFDITLFERIEFLSRANGFCNSVSPLSQKQRIVQLASRIQDACEVAGIQGDILSLVYTDARIDSAIKDELIKTLDGKILSTSELFNDFAVPLSYHEIALFIFKIADFRDHEVIMAKWDELFQSLRMEFNNTGKKEDSMNFINLLSNVLIKIGKNVQDSEFIFPIFELFPIVCNFFYETLPKEHIVSGSIVSIFITAGVSFNKMYYILKELIETSDSDNSVFNKEMTWLIHEWYKSDRKFRDIISYNDIIHLKEYKIDNDPIEKYVKNSGNNLGICFYKE", "length": 1502 }, "evidence": [ { "id": "F1NPS0", "url": "https://omabrowser.org/oma/group/F1NPS0/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q54F20-1", "protein_name": "Nucleoporin 155", "gene_name": "nup155", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MRQSQLYPNLGYNNQNGQFNYLPSPEQQSIYRNNIQTPTSGISNNLFPLQSQQRIIQPQYHYQTPLINNNIINNNNNINNNNIVYQQDQQTQPQAQPQQQPQQTQTQSPSQQEKEQEQQQQELKEQQQKQQQQQEQEQQELMRQKKTNSLLSITPFNKEEDLKKIFLNSIESIDSSIDKVATIPDPTLKVLYKRDPGFNYFDGGSYFWSTLVIEKHIELPQEITNGYLSTSTKSLLGLFPEIGRAWISIDQTLYLWDYRDSGELISHNLSQIITNCALIQPKKNTFKDAVKKVMVVCTHVEIFLFALCYSNETKFEILSTLSIPSDNIFITDIVGTKEGRIFLSGQDGNIYEIEYSKDNLFWFSNEKIKKINLTQTFFNSFINLSKKKEIIQLIYDEDRYLLYSLSKDSTINVYSLGKIGDKFEHLKTIYPINDIDSLFNNNINNNNNNNNYYSQQYQYQQQQQNQQYQQSQYGQQQQQQQPNQYGQQQQQQQPLQQQQQQQQQQQQNFSRKNMVIMSIHISPKETEFNFIAILSSGERLYYTLNRLAYIRSPPNNVDNNGNSNIHYTYYSNGVFFTASEVSDQEDRLVGTTLFGNDIIKSHYETSKSGFSNQISQDTLSEKSNLFSIRGRVSVIKEDIVNDGKPTVYYKELSNEHMNTPRRFLCLNSLGLHFISKLRYVDLLQNILSSNNPQDIDNFFDAFGKIIASSLCISLYCSSPHSSILLHDQVYSGISIPKTTTTRIADLAMTFLRRKSGKPQYYQPVVIQQMFGDMGAPVNKTELMYSNAYNGLLAYLARVLYPLWNQSVVTSAGCSYWSIVQLQLFQSHLSNLLSFLDISQLIPKGQEIPIIKIATNKTSSTTTTTTTANNSSSNEIYGEDEAIKNEKRSLIGLKNIIVKSIQILNLFLILSQYNFKQLFDSSSIELDIKRKIDLLKFRDILNSDILGKNLPLPTISSLTTSTTTTTTTTTTSTTSSSSSSTSPLTTSTSNSTLTLLIDSLMKTLNSHNINIDQVSNQLETECPIFFKKENRELYKVKEKLNMVLRDGSTYFTDSLVKDSALILDSISPNYNLSEIVDLFIAIKAFNYVTPLCLQYAQDLDPRGITLIPSNNPSDEFKLKLSQKKSTFQEIIKLLNFIQSDNNNNNNNSGGGGGDNNNYNNTFEIIDIIIQQVLVCQDRLAHEMIYSWILNNGMTSKFFEINTPFITEFLFANDIDLCWKVLAKHQELLKAVHVLFQIAERSTTLDEKILAYTNCTMILSEQKDEDAYIQAKNQITFANIQKQIVLQLENYLNNPNESNNRNNSSNNNGGQPFDINQIKESISNLNKTIFDITTLFTDYARKYYLHEQMLYLCHIGNHSDQNFIQILWKIIIDKEIPPPSSNLSLDDNAENDDGLKISVGGVIESLVSKISNIGYDFYPNEITFPVEFIINYGERAIFNFSRNKSEAEKKEISPNWLTSSLHDHVKIDYWILVDYYNNTIEKGSWKEEDESLIYITSVYFYLVESLINTIQTATERRLFSSKQILQSLENRESTFKSIFNRQRSSLNQETIKKLEQLLIKFEKIISISKSFKDFRGY", "length": 1575 }, "evidence": [ { "id": "F1NPS0", "url": "https://omabrowser.org/oma/group/F1NPS0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q99P88-1", "protein_name": "Nuclear pore complex protein Nup155", "gene_name": "Nup155", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPSVLGSMMVASTSAAASLQEALENAGRLIDRQLQEDRMYPDLSELLMVSAPNSPTVSGMSDMDYPLQGPGLLSVPSLPEISTIRRVPLPPELVEQFGHMQCNCMMGVFPPISRAWLTIDSDIFMWNYEDGGDLAYFDGLSETILAVGLVKPKAGIFQPHVRHLLVLATPVDIVILGLSYANVQTGSGILNDSMCGGMQLLPDPLYSLPTDNTYLLTITSTDNGRIFLAGKDGCLYEVAYQAEAGWFSQRCRKINHSKSSLSFLVPSLLQFTFSEDDPIVQIEIDNSRNILYTRSEKGVIQVYDLGHDGQGMSRVASVSQNAIVSAAGNIARTIDRSVFKPIVQIAVIESSESLDCQLLAVTHAGVRLYFSTCPFRQPLARPNTLTLVHVRLPPGFSASSTVEKPSKVHKALYSKGILLMTASENEDNDILWCVNHDTFPFQKPMMETQMTTRVDGHSWALSAIDELKVDKIITPLNKDHIPITDSPVVVQQHMLPPKKFVLLSAQGSLMFHKLRPVDQLRHLLVSNVGGDGEEIERFFKLHQEDQACATCLILACSTAACDREVSAWATRAFFRYGGEAQMRFPATLPTPSNVGPILGSPMYSSSPVPSGSPYPNPSSLGTPSHGAQPPTMSTPMCAVGSPAMQAASMSGLTGPEIVYSGKHNGICIYFSRIMGNIWDASLVVERVFKSSNREITAIESSVPVQLLESVLQELKGLQEFLDRNSQFSGGPLGNPNTTARVQQRLVGFMRPENGNTQQMQQELQRKFQEAQLSEKISLQAIQQLVRKSYQALALWKLLCEHQFSVIVGELQKEFQEQLKITTFKDLVIRDKEVTGALIASLINCYIRDNAAVDGISLHLQDTCPLLYSTDDAVCSKANELLQRSRQVQSKTERERMLRESLKEYQKISNQVDLPSVCAQYRQVRFYEGVVELSLTAAEKKDPQGLGLHFYKHGEPEEDVVGLQTFQERLNSYKCITDTLQELVNQSKAAPQSPSVPKKPGPPVLSSDPNMLSNEEAGHHFEQMLKLAQRSKDELFSIALYNWLIQADLADKLLQIASPFLEPHLVRMARVDQNRVRYMDLLWRYYEKNRSFSSAARVLSKLADMHSTEISLQQRLEYIARAILSAKSSTAISSIAADGEFLHELEEKMEVARIQLQIQETLQRQYSHHSSVQDAISQLDSELMDITKLYGEFADPFKLAECKLAVIHCAGYSDPILVHTLWQDIIEKELNDSVALSSSDRMHALSLKLVLLGKIYAGTPRFFPLDFIVQFLEQQVCTLNWDVGFVIQTMNEIGVPLPRLLEVYDQLFKSRDPFWNRVKSPLHLLDCIHVLLTRYVENPSLVLNCERRRFTNLCLDAVCGYLVELQSMSSSVAVQAITGNFKSLQAKLERLH", "length": 1391 }, "evidence": [ { "id": "F1NPS0", "url": "https://omabrowser.org/oma/group/F1NPS0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9V463-1", "protein_name": "Nuclear pore complex protein Nup154", "gene_name": "Nup154", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MTLPQAQLDFFTTATSMLEWHYNLERNKPGLLELTGVSQHGRATMSGLNDYDYQSLSFLKSDRTHNLQQMRTVTKSAIPNEILEHFKHIKCHCTMGLFPEIGRAWLTIDSEIYIWTFNQTRDVAYYDGLSHLIVSVGLVKPKPGVFVQDVKYLLVLTTPIEVIVLGVTFGESSYNEMQLMNRPVFVIGTDNVSISVIKGTDDGRIFLGGRDGCLYEIYYQAESSWFGKRCKKINLSQGLVSYMVPSFLKVFSEVDPIEHIEIDNSRKLLYVLTEKGVIEAWDISTSYTTARRLGRITQNDITNQAVSLITTVDPSIFKSVKAICPLSADDADKLHLVAVTQCGVRLFFSTTSLNVKQQFGPAVPCSPGENTGFGQPAVQPPLSPNAEAPKGLYLLHVRLPPGYTPNATTNKPKQVHAAHYTEGTMLMITTQQHEQDLLWSLSSAPSVNFTYLVESTALESLDGVVWGLAEVHEPSTPQRKSPLNSARHARKVALLTNQGTHIIEVLKMVDVLRQILLSCNGPHHEEVKMFFQSQNQREACVTALLLATSDTYRGSDVALWAAQAFMLYGGEPCYQHQKFLNASNRNMANQTLGPNTTNVRERQSMFMSTPMPNSVANSPVGFPGSQFNQPISPIGNMQPPQVAVSNENSPIVFSAKHDGLYMYVSRMLHSVWQMRCVNEQFCSNLSQSECALLLSDLRSLRSFLEVHSVHDISSTTRVSFDNHLDRTNSYNTIMMGNTLLPIPEQRVLSEQAQVEETRSLSALNLFVKHACEVISLWNILNSHSFQLICVQLSPEHQKLLTCSTFRDLLITRSEVCAFLIISLINLYLKDAAGVSEVSKNLRENCPNLYRHEDDVTYKATELLMNAKNCTSATEKEHMLRTTLHMCKEAAPTLPLHSICMQFISADFFEGVIELSAVCASKSDPEEVGVHFYNNGEPADDREGYTCFATRMAYYKEVQLMLDHIYQRVCNKTHVQDKSINPLKGTAKASDAKNGATQTIPKIVAHTLKVKDPLIHITLYEWLLAHDMLKELLDVVEPSLGEFLRRSVSQNVDNVVLIDLLWKYYEKNSHHSQAAHILDNLAMTRSENINLEQRIEYLVRAVMCMRNGNVGSSLSNGIFLKELEDKLDIARVQKSVLAAMTELASDKLEAATAVKELNYALYDITQLYQHFAEPFDLWECQLSILNCSHHNDPLLIESVWGQIINSVVDKPGTTSERCNRLFTKIEILVREYGESGVCFPFAFLIRELEVKACQLRFPEGIVPEKLVSMNLDIELLLEYYSRMISMNERVWANEGNEWHLIQSVIRVVSLLADNAQSIWYRSKRRIVGKAQDIVAGCLNICYQKPDTNRLQHSLKELQSQLQRLLI", "length": 1365 }, "evidence": [ { "id": "F1NPS0", "url": "https://omabrowser.org/oma/group/F1NPS0/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nuclear membrane", "id": "GO:0031965", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031965", "evidence": [ { "database": "UniProtKB", "id": "F1NPS0", "url": "https://www.uniprot.org/uniprotkb/F1NPS0" } ], "pmid": "" }, { "name": "nuclear pore inner ring", "id": "GO:0044611", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044611", "evidence": [ { "database": "UniProtKB", "id": "F1NPS0", "url": "https://www.uniprot.org/uniprotkb/F1NPS0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "structural constituent of nuclear pore", "id": "GO:0017056", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017056", "evidence": [ { "database": "UniProtKB", "id": "F1NPS0", "url": "https://www.uniprot.org/uniprotkb/F1NPS0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "mRNA transport", "id": "GO:0051028", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051028", "evidence": [ { "database": "UniProtKB", "id": "F1NPS0", "url": "https://www.uniprot.org/uniprotkb/F1NPS0" } ], "pmid": "" }, { "name": "protein localization to nuclear inner membrane", "id": "GO:0036228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036228", "evidence": [ { "database": "UniProtKB", "id": "F1NPS0", "url": "https://www.uniprot.org/uniprotkb/F1NPS0" } ], "pmid": "" }, { "name": "RNA export from nucleus", "id": "GO:0006405", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006405", "evidence": [ { "database": "UniProtKB", "id": "F1NPS0", "url": "https://www.uniprot.org/uniprotkb/F1NPS0" } ], "pmid": "" }, { "name": "transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery", "id": "GO:0000972", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000972", "evidence": [ { "database": "UniProtKB", "id": "F1NPS0", "url": "https://www.uniprot.org/uniprotkb/F1NPS0" } ], "pmid": "" }, { "name": "protein import into nucleus", "id": "GO:0006606", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006606", "evidence": [ { "database": "UniProtKB", "id": "F1NPS0", "url": "https://www.uniprot.org/uniprotkb/F1NPS0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1089, "end_pos": 1091, "annotation": "n_glycosylation_sequon" }, { "start_pos": 184, "end_pos": 186, "annotation": "n_glycosylation_sequon" }, { "start_pos": 248, "end_pos": 250, "annotation": "n_glycosylation_sequon" }, { "start_pos": 983, "end_pos": 985, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1NPS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NPS0" }, { "id": "PF03177", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03177" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Nucleoporin Nup133/Nup155-like C-terminal", "eco_id": "ECO_0000259", "start_pos": 655, "end_pos": 1362, "start_aa": "Ser", "end_aa": "Gln", "glycosite_overlap": "" }, { "evidence": [ { "id": "F1NPS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NPS0" }, { "id": "PF08801", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08801" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Nucleoporin Nup133/Nup155-like N-terminal", "eco_id": "ECO_0000259", "start_pos": 72, "end_pos": 501, "start_aa": "Pro", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 735 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1089, "end_pos": 1091 }, { "start_pos": 184, "end_pos": 186 }, { "start_pos": 248, "end_pos": 250 }, { "start_pos": 983, "end_pos": 985 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1NQ63-1", "uniprot_ac": "F1NQ63", "uniprot_id": "F1NQ63_CHICK", "mass": { "chemical_mass": 77689.0, "monoisotopic_mass": 77689.0 }, "refseq": { "ac": "NP_001034186", "name": "solute carrier organic anion transporter family member 1C1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001034186" }, "gene_names": [ { "name": "SLCO1C1", "type": "recommended", "evidence": [ { "id": "F1NQ63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NQ63" } ] }, { "name": "SLCO1C1", "type": "synonym", "evidence": [ { "id": "NP_001034186", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001034186" } ] } ], "protein_names": [ { "name": "Solute carrier organic anion transporter family member", "type": "recommended", "evidence": [ { "id": "F1NQ63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NQ63/entry#names_and_taxonomy" } ] }, { "name": "organic anion transporting polypeptide 1c1", "type": "synonym", "evidence": [ { "id": "NP_001034186", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001034186" } ] }, { "name": "solute carrier organic anion transporter family member 1C1", "type": "synonym", "evidence": [ { "id": "NP_001034186", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001034186" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: ERR2368565.399722.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992482 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## CDS uses downstream in-frame AUG :: upstream AUG and CDS extension is not conserved ##RefSeq-Attributes-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000012.1. On Dec 6, 2021 this sequence version replaced NP_001034186.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001034186", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001034186" } ] }, { "annotation": "Oatp1c1 is expressed in the choroid plexus from day 3 to day 10 of development in chicken embryo.", "evidence": [ { "database": "RefSeq", "id": "NP_001034186", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001034186" }, { "database": "PubMed", "id": "22771619", "url": "https://glygen.org/publication/PubMed/22771619" } ] }, { "annotation": "We have identified seven genes in which expression levels in different tissues were associated with eggshell color.", "evidence": [ { "database": "RefSeq", "id": "NP_001034186", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001034186" }, { "database": "PubMed", "id": "24612318", "url": "https://glygen.org/publication/PubMed/24612318" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NQ63", "url": "https://www.uniprot.org/uniprotkb/F1NQ63" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SLCO1C1", "url": "https://www.uniprot.org/uniprotkb/F1NQ63", "locus": { "chromosome": "1", "start_pos": 65218277, "end_pos": 65196182, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010015162", "url": "https://www.ensembl.org/id/ENSGALG00010015162" } ] } } ], "crossref": [ { "id": "F1NQ63", "url": "https://alphafold.ebi.ac.uk/entry/F1NQ63", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000013154", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000013154", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd17459", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd17459", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "418186", "url": "https://www.ncbi.nlm.nih.gov/gene/418186", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002350", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002350", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004156", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004156", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020846", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020846", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036058", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036058", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036259", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036259", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:418186", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418186", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "ISYDKHP", "url": "https://omabrowser.org/oma/group/ISYDKHP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YT61", "url": "https://www.orthodb.org/?gene=A0A8V0YT61", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NQ63", "url": "https://www.orthodb.org/?gene=F1NQ63", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11388", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11388", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11388:SF99", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11388:SF99", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03137", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03137", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07648", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07648", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-879518", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-879518", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001034186", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001034186", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "71815", "url": "https://www.rhea-db.org/rhea/71815", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "71819", "url": "https://www.rhea-db.org/rhea/71819", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "73311", "url": "https://www.rhea-db.org/rhea/73311", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YT61", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YT61", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YT61-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YT61-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NQ63", "url": "https://www.uniprot.org/uniprotkb/F1NQ63", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NQ63-1", "url": "https://www.uniprot.org/uniprotkb/F1NQ63-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEISSKENAQLFSNNAVLPVDRSSFKSESSTSKEKQSCCGGIKIFLGALSFVYFAKALSGSYLKSTITQIERRFDIPSSLVGVIDGSFEIGNLLIIVFVSYFGAKLHRPRIIGAGCLIMSAGTFLIAMPQFFMGRYQYERFPSTINSTVSISPCLQEKSQTPLSALEKSQAKVNAGCEKAGSSMWIYVFLGNLLRGIGETPIQPLGITYIDDYAIEENAALYIGCVQTLAIIGPIFGFLLGSLCAKLYVDIGFVDLDSITITHKDVQWVGAWWLGYLIAGVISVLAGIPFWFLPKHLPKPESRKDSSTSSEQSKFITQDNKEQQKSYQPQMKVAEMAKDFLPSLKNLFGNPVYSLFLCASILHFNSLIGMVTYKPKYIEQQYGQTSSKTNFVIGLINIPAVAFGIFSGGLIMKKFRINVLGAAKISLGSSFFGYLLLLSLFAMGCENSDVAGLTVSYHGTKQKVGYEQGLFSECNLGCMCSQNDWDPICGENGITYISACLAGCQASNGSGKNTVFFNCSCVGIMASPSRSSSAVMGPCQKGNECPKMFLYFLVISVITSYTLSVGGTPGYILLLRCIKPHLKSFALGIYTLAIRVLAGIPAPVYFGVAIDTTCLKWGRKRCGGRGACRLYDSSALRYVYLGLTLVLGTVSIFFSIAVLWVLRKRSALQDETLSANGERDTCVTKSRKDNFVNSDHLIQTTYWPEKETRL", "length": 710, "header": "tr|F1NQ63-1|F1NQ63_CHICK Isoform 1 of Solute carrier organic anion transporter family member OS=Gallus gallus OX=9031 GN=SLCO1C1 PE=3 SV=1 CANONICAL=F1NQ63-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YT61-1", "url": "https://www.uniprot.org/uniprotkb/F1NQ63/entry#A0A8V0YT61-1", "sequence": { "sequence": "MEISSKENAQLFSNNAVLPVDRSSFKSESSTSKEKQSCCGGIKIFLGALSFVYFAKALSGSYLKSTITQIERRFDIPSSLVGVIDGSFEIGNLLIIVFVSYFGAKLHRPRIIGAGCLIMSAGTFLIAMPQFFMGRYQYERFPSTINSTVSISPCLQEKSQTPLSALEKSQAKVNAGCEKAGSSMWIYVFLGNLLRGIGETPIQPLGITYIDDYAIEENAALYIGCVQTLAIIGPIFGFLLGSLCAKLYVDIGFVDLDSITITHKDVQWVGAWWLGYLIAGVISVLAGIPFWFLPKHLPKPESRKDSSTSSEQSKFITQDNKEQQKSYQPQMKVAEMAKGLINIPAVAFGIFSGGLIMKKFRINVLGAAKISLGSSFFGYLLLLSLFAMGCENSDVAGLTVSYHGTKQKVGYEQGLFSECNLGCMCSQNDWDPICGENGITYISACLAGCQASNGSGKNTVFFNCSCVGIMASPSRSSSAVMGPCQKGNECPKMFLYFLVISVITSYTLSVGGTPGYILLLRCIKPHLKSFALGIYTLAIRVLAGIPAPVYFGVAIDTTCLKWGRKRCGGRGACRLYDSSALRYVYLGLTLVLGTVSIFFSIAVLWVLRKRSALQDETLSANGERDTCVTKSRKDNFVNSDHLIQTTYWPEKETRL", "length": 655, "header": "tr|A0A8V0YT61-1|A0A8V0YT61_CHICK Computationally mapped isoform of Solute carrier organic anion transporter family member OS=Gallus gallus OX=9031 GN=SLCO1C1 PE=3 SV=1 CANONICAL=F1NQ63-1" }, "locus": { "chromosome": "1", "start_pos": 65217437, "end_pos": 65196199, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010036537.1", "url": "https://www.ensembl.org/id/ENSGALT00010036537.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021286.1", "url": "https://www.ensembl.org/id/ENSGALP00010021286.1" } ] } }, { "isoform_ac": "F1NQ63-1", "url": "https://www.uniprot.org/uniprotkb/F1NQ63/entry#F1NQ63-1", "sequence": { "sequence": "MEISSKENAQLFSNNAVLPVDRSSFKSESSTSKEKQSCCGGIKIFLGALSFVYFAKALSGSYLKSTITQIERRFDIPSSLVGVIDGSFEIGNLLIIVFVSYFGAKLHRPRIIGAGCLIMSAGTFLIAMPQFFMGRYQYERFPSTINSTVSISPCLQEKSQTPLSALEKSQAKVNAGCEKAGSSMWIYVFLGNLLRGIGETPIQPLGITYIDDYAIEENAALYIGCVQTLAIIGPIFGFLLGSLCAKLYVDIGFVDLDSITITHKDVQWVGAWWLGYLIAGVISVLAGIPFWFLPKHLPKPESRKDSSTSSEQSKFITQDNKEQQKSYQPQMKVAEMAKDFLPSLKNLFGNPVYSLFLCASILHFNSLIGMVTYKPKYIEQQYGQTSSKTNFVIGLINIPAVAFGIFSGGLIMKKFRINVLGAAKISLGSSFFGYLLLLSLFAMGCENSDVAGLTVSYHGTKQKVGYEQGLFSECNLGCMCSQNDWDPICGENGITYISACLAGCQASNGSGKNTVFFNCSCVGIMASPSRSSSAVMGPCQKGNECPKMFLYFLVISVITSYTLSVGGTPGYILLLRCIKPHLKSFALGIYTLAIRVLAGIPAPVYFGVAIDTTCLKWGRKRCGGRGACRLYDSSALRYVYLGLTLVLGTVSIFFSIAVLWVLRKRSALQDETLSANGERDTCVTKSRKDNFVNSDHLIQTTYWPEKETRL", "length": 710, "header": "tr|F1NQ63-1|F1NQ63_CHICK Isoform 1 of Solute carrier organic anion transporter family member OS=Gallus gallus OX=9031 GN=SLCO1C1 PE=3 SV=1 CANONICAL=F1NQ63-1" }, "locus": { "chromosome": "1", "start_pos": 65217437, "end_pos": 65196199, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010036540.1", "url": "https://www.ensembl.org/id/ENSGALT00010036540.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021289.1", "url": "https://www.ensembl.org/id/ENSGALP00010021289.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 568, "start_aa": "Thr", "end_pos": 568, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr568", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "Dynamic mRNA distribution pattern of thyroid hormone transporters and deiodinases during early embryonic chicken brain development.", "journal": "Neuroscience", "date": "2012-09-27", "authors": "Geysens S, Ferran J L, Van Herck S L J, Tylzanowski P, Puelles L, Darras V M", "evidence": [ { "database": "RefSeq", "id": "NP_001034186", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001034186" } ], "reference": [ { "type": "PubMed", "id": "22771619", "url": "https://glygen.org/publication/PubMed/22771619" } ] }, { "title": "Quantitative expression of candidate genes affecting eggshell color.", "journal": "Animal science journal = Nihon chikusan Gakkaiho", "date": "2014-05", "authors": "Zheng Chuanwei, Li Zesheng, Yang Ning, Ning Zhonghua", "evidence": [ { "database": "RefSeq", "id": "NP_001034186", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001034186" } ], "reference": [ { "type": "PubMed", "id": "24612318", "url": "https://glygen.org/publication/PubMed/24612318" } ] } ], "pathway": [ { "id": "gga:418186", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418186", "resource": "KEGG Pathway" }, { "id": "R-GGA-879518", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-879518", "resource": "Reactome", "description": "Organic anion transport by SLCO transporters" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3L7H6L9-1", "protein_name": "Solute carrier organic anion transporter family member", "gene_name": "Slco1c1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MDTSSKKNSHLFHKTPARPVRRQSLKVGCPSPEEARPCCGELKVFLGALSFVYFAKALAEGYLKSTITQIERRFDIPSSLVGIIDGSFEIGNLLVITFVSYFGSRLHRPKIIGAGCLVMGVGTMLIAMPQFFMEKYRYEKYEKYSPSSNLTPNVSPCHLELSSLSPSSVMGKSQNKINDECEGDASSSMWVYVFLGNLLRGLGETPIQPLGIAYLDDFASEDNAAFYIGCVQTVAIIGPIFGFLLGSLCAKLYVDIGFVNLDHITITPKDPQWVGAWWLGYLIAGLLSLLAAVPFWCLPKTLPRSQGREDPGSSSEKSKFIIDDPISYQMAPGEEMKMVEMARNFLPSLKTLLRNPVYILYLCASTVQFNSLFGMVTYKPKYIEQQYGQSSSKANFFIGLINIPAVALGIFSGGIVMKKFRLGVFEATKLYLGSSVFGYLLFLSLFALGCENPGVAGLTVSYQGTKPVSYHERALFSDCNSRCKCSESKWEPMCGDNGITYVSACLAGCQSSSQSGKNIIFSNCTCVGLAAPTSGNWSGMMGRCQKDNGCPQMFLYFLVISVITSYTLSLGGIPGYILLLRCIQPQLKSFALGIYTLAVRVLAGIPAPVYFGVLIDTSCLKWGFKKCGSRGSCRLYDSHAFRHIYLGLTTLLGTVSIFLSMAVLFVLKRKYVSKHSSFITTRDKAVVSSTFRKETSVARVHVPQPKYWPGKETRL", "length": 715 }, "evidence": [ { "id": "F1NQ63", "url": "https://omabrowser.org/oma/group/F1NQ63/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "E1BC23-1", "protein_name": "Solute carrier organic anion transporter family member", "gene_name": "SLCO1C1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MDTSSKENIRLFSKNSMQPVGRLSFQTEYPSPEEKQPCCGQLKVFLGALSFVYFAKALAEGYLKSTITQIERRFDIPSSLVGIIDGSFEIGNLLVIAFVSYFGAKLHRPKIIGAGCLIMGVGTLLIAMPQFFMEHYKYERYSPVSNSTLSISPCLLDSNNSLPIPVAEKSQSKINNECQIDASSSMWVYVFLGNLLRGFGETPIQPLGIAYLDDFASQDNAAFYIGCVQTVAIIGPIFGFLLGSLCAKLYVDIGFVNLDHITITPKDPQWVGAWWLGYLIAGSITLLAAVPFWCLPRTLPRPRSREDSSSSSEKSKFIMDDHTDYQTPPGEKAKIMEMARDFLPSLKSLFGNPVYFLYLCASTVQFNSLFGMVTYKPKYIEQQYGQSASKANFVIGLINIPAVALGIFSGGIVMKKFRISICGAAKLYLGSSVLGYLLFLSLFALGCENSDVAGLTISYQGTKPVSYHERALFSDCNSRCKCSETKWEPICGENGITYASACLAGCQTTTGSGKTTVFNNCTCVGLAASKSGNSTGMVGRCQKDNGCAKMFLYFLVIAVITSYTLSVGGIPGYILLLRCIKPQLKSFALGIYTLAVRVLAGIPSPIYFGVLIDTSCLKWGFKRCGSKGSCRLYDSNAFRHIYLGLTMMLGIMSIFLSTAVLFTLKKNYVSKHRSFRTKRERTMVSTRIRKENCTTSDHLLQPNYWPGKETQL", "length": 712 }, "evidence": [ { "id": "F1NQ63", "url": "https://omabrowser.org/oma/group/F1NQ63/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q9EPZ7-1", "protein_name": "Solute carrier organic anion transporter family member 1C1", "gene_name": "Slco1c1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDTSSKENAHLFHKNSAQPAGGPSFKAGYPSTEEARPCCGKLKVFLGALSFVYFAKALTEGYLKSTITQIERRFDIPSSLVGIIDGSFEIGNLLVITFVSYFGAKLHRPKIIGAGCLVMGFGTMLIAVPQFFMEKYSYEKYERYSPSSNLTPNISPCYLESSSPSPRSIVGKSQNKINDECEVDTSSSMWVYVFLGNLLRGLGETPIQPLGIAYLDDFASEDNAAFYIGCVQTVAIIGPIFGFLLGSLCAKLYVDIGFVNLDHITITPKDPQWVGAWWLGYLIAGFLSLLAAVPFWCLPKTLPRSQSREDSGSSSEKSKFITDDPVNYQMAPREESMKIMEMARDFLPSLKSLFRNPVYILYLCASTVQFNSLFGMVTYKPKYIEQQYGQSSSKANFVIGLINIPAVALGIFSGGIVMKKFRLGICEATKLYLGSSVFGYLLFLSLFALGCENSSVAGLTVSYQGTKPVSYHERALFSDCNSRCKCSDSKWEPMCGDNGITYASACLAGCQSSSRSGKNIIFSNCTCVGFAAPKSGNWSGMMGRCQKDNGCSQMFLYFLVISVITSYTLSLGGIPGYILLLRCIQPQLKSFALGIYTLAVRVLAGIPAPVYFGVLIDTSCLKWGFKKCGSRGSCRLYDSHAFRHIYLGLTTLLGTVSVFLSTAVLLVLKKKYVSKRSSFITAREKIVMSSSVKKETCAARDHGLQPKYWPGKETRL", "length": 716 }, "evidence": [ { "id": "F1NQ63", "url": "https://omabrowser.org/oma/group/F1NQ63/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9ERB5-1", "protein_name": "Solute carrier organic anion transporter family member 1C1", "gene_name": "Slco1c1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDTSSKENAHLFHKNSAQPAGGPSFTVGYPSTEEARPCCGKLKVFLGALSFVYFAKALAEGYLKSTVTQIERRFEIPSSLVGIIDGSFEIGNLLVITFVSYFGAKLHRPKIIGAGCLVMGFGTMLIAVPQFFMEKYSYEKYERYSPSSNVTPSISPCYLESSSPSPSSILGKSQNKISHECVGDSSSSMWVYVFLGNLLRGLGETPIQPLGIAYLDDFASEDNAAFYIGCVQTVAIIGPIFGFLLGSLCAKLYVDIGFVNLDHITITPKDPQWVGAWWLGYLIAGFLSLLAAVPFWCLPKTLPRSQSRENSGSTSEKSKFIDDPIHYQMAPGDDKMKIMEMAKDFLPSLKTLFRNPVYILYLCASTVQFNSLFGMVTYKPKYIEQQYGQSSSKANFVIGLINIPAVALGIFSGGIVMKKFRLGICEATKLYLGSSVFGYLLFLSLFALGCENSSVAGLTVSYQGTKPVSYHERALFSDCNSRCKCSDSKWEPMCGDNGITYVSACLAGCQSSSRSGKNIIFSNCTCVGFAAPKSGNWSGMMGRCQKDNGCSQMFLYFLVISVITSYTLSLGGIPGYILLLRCIQPQLKSFALGIYTLAVRVLAGIPAPVYFGVLIDTSCLKWGFKKCGSRGSCRLYDSHAFRHIYLGLTTLLGTVSVFLSMAVLFVLKKKYVSKHSSLITTREKIGMSSSIKKETCAARDRGLQPKYWPGKETRL", "length": 715 }, "evidence": [ { "id": "F1NQ63", "url": "https://omabrowser.org/oma/group/F1NQ63/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9NYB5-1", "protein_name": "Solute carrier organic anion transporter family member 1C1", "gene_name": "SLCO1C1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDTSSKENIQLFCKTSVQPVGRPSFKTEYPSSEEKQPCCGELKVFLCALSFVYFAKALAEGYLKSTITQIERRFDIPSSLVGVIDGSFEIGNLLVITFVSYFGAKLHRPKIIGAGCVIMGVGTLLIAMPQFFMEQYKYERYSPSSNSTLSISPCLLESSSQLPVSVMEKSKSKISNECEVDTSSSMWIYVFLGNLLRGIGETPIQPLGIAYLDDFASEDNAAFYIGCVQTVAIIGPIFGFLLGSLCAKLYVDIGFVNLDHITITPKDPQWVGAWWLGYLIAGIISLLAAVPFWYLPKSLPRSQSREDSNSSSEKSKFIIDDHTDYQTPQGENAKIMEMARDFLPSLKNLFGNPVYFLYLCTSTVQFNSLFGMVTYKPKYIEQQYGQSSSRANFVIGLINIPAVALGIFSGGIVMKKFRISVCGAAKLYLGSSVFGYLLFLSLFALGCENSDVAGLTVSYQGTKPVSYHERALFSDCNSRCKCSETKWEPMCGENGITYVSACLAGCQTSNRSGKNIIFYNCTCVGIAASKSGNSSGIVGRCQKDNGCPQMFLYFLVISVITSYTLSLGGIPGYILLLRCIKPQLKSFALGIYTLAIRVLAGIPAPVYFGVLIDTSCLKWGFKRCGSRGSCRLYDSNVFRHIYLGLTVILGTVSILLSIAVLFILKKNYVSKHRSFITKRERTMVSTRFQKENYTTSDHLLQPNYWPGKETQL", "length": 712 }, "evidence": [ { "id": "F1NQ63", "url": "https://omabrowser.org/oma/group/F1NQ63/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "F1NQ63", "url": "https://www.uniprot.org/uniprotkb/F1NQ63" } ], "pmid": "" }, { "name": "basolateral plasma membrane", "id": "GO:0016323", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016323", "evidence": [ { "database": "UniProtKB", "id": "F1NQ63", "url": "https://www.uniprot.org/uniprotkb/F1NQ63" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "monoatomic ion transport", "id": "GO:0006811", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006811", "evidence": [ { "database": "UniProtKB", "id": "F1NQ63", "url": "https://www.uniprot.org/uniprotkb/F1NQ63" } ], "pmid": "" }, { "name": "bile acid and bile salt transport", "id": "GO:0015721", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015721", "evidence": [ { "database": "UniProtKB", "id": "F1NQ63", "url": "https://www.uniprot.org/uniprotkb/F1NQ63" } ], "pmid": "" }, { "name": "sodium-independent organic anion transport", "id": "GO:0043252", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043252", "evidence": [ { "database": "UniProtKB", "id": "F1NQ63", "url": "https://www.uniprot.org/uniprotkb/F1NQ63" } ], "pmid": "" }, { "name": "positive regulation of thyroid hormone generation", "id": "GO:2000611", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000611", "evidence": [ { "database": "UniProtKB", "id": "F1NQ63", "url": "https://www.uniprot.org/uniprotkb/F1NQ63" } ], "pmid": "" }, { "name": "lipid transport", "id": "GO:0006869", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006869", "evidence": [ { "database": "UniProtKB", "id": "F1NQ63", "url": "https://www.uniprot.org/uniprotkb/F1NQ63" } ], "pmid": "" }, { "name": "transmembrane transport", "id": "GO:0055085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055085", 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"binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 381, "end_pos": 383 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { 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"total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1NQ85-1", "uniprot_ac": "F1NQ85", "uniprot_id": "F1NQ85_CHICK", "mass": { "chemical_mass": 75275.0, "monoisotopic_mass": 75275.0 }, "refseq": { "ac": "XP_421405", "name": "transcription factor IIIB 90 kDa subunit isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_421405" }, "gene_names": [ { "name": "BRF1", "type": "recommended", "evidence": [ { "id": "F1NQ85", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NQ85" } ] }, { "name": "BRF1", "type": "synonym", "evidence": [ { "id": "XP_421405", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_421405" } ] } ], "protein_names": [ { "name": "Transcription factor IIIB 90 kDa subunit", "type": "recommended", "evidence": [ { "id": "F1NQ85", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NQ85/entry#names_and_taxonomy" } ] }, { "name": "B-related factor 1", "type": "synonym", "evidence": [ { "id": "F1NQ85", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NQ85/entry#names_and_taxonomy" } ] }, { "name": "transcription factor IIIB 90 kDa subunit isoform X1", "type": "synonym", "evidence": [ { "id": "XP_421405", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_421405" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052536.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Nov 16, 2006 this sequence version replaced XP_421405.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_421405", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_421405" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NQ85", "url": "https://www.uniprot.org/uniprotkb/F1NQ85" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "BRF1", "url": "https://www.uniprot.org/uniprotkb/F1NQ85", "locus": { "chromosome": "5", "start_pos": 52179113, "end_pos": 52340401, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010017110", "url": "https://www.ensembl.org/id/ENSGALG00010017110" } ] } } ], "crossref": [ { "id": "F1NQ85", "url": "https://alphafold.ebi.ac.uk/entry/F1NQ85", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000011705", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000011705", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd20553", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd20553", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd20554", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd20554", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "423503", "url": "https://www.ncbi.nlm.nih.gov/gene/423503", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000812", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000812", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011665", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011665", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013137", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013137", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013150", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013150", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013763", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013763", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036915", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036915", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "EPPCKVM", "url": "https://omabrowser.org/oma/group/EPPCKVM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1NQ85", "url": "https://www.orthodb.org/?gene=F1NQ85", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11618", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11618", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11618:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11618:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00382", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00382", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07741", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07741", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08271", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08271", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-76061", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-76061", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-76066", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-76066", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_421405", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_421405", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1NQ85", "url": "https://www.uniprot.org/uniprotkb/F1NQ85", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NQ85-1", "url": "https://www.uniprot.org/uniprotkb/F1NQ85-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPGGRVCAACGCSEIEVDAARGDAVCTGCGSVLEDNIIVSEVQFVENSGGGSSAVGQFVSLDGAGKTPTLGGGFHANLGKESRAQTLQNGKRQIHHLGNQLQLNQHCLDTAFNFFKMAVSKHLTRGRKMTHVIAACLYLVCRTEGTPHMLLDLSDLLQVNVYVLGKTFLLLARELCINAPAIDPCLYIPRFAHMLEFGDKNHEVSMTALRLLQRMKRDWMHTGRRPSGLCGAALLVAARMHDFRRTVKEVIRVVKVCESTLRKRLTEFEYTPTSQLTIDEFMRIDLEEECDPPSFTAGQKKLKIQQLEKALSKKLEDFEGEISSYQDEIEIELENSRPKAKGVFANLSKSDSIEDNTLSIFGEEEAEDEELEAAANHLNKDFCNELLEKDRLKPGEDGDCKNGNEAPVRPPALESLLGPLPTAASLGITESIKECISSKDREPGENTGDGELDLSGIDDSEIDRYILNETEAQIKAELWMKENADYLKEQKEKEARIAKEKELGIYKEHKPKKAAKKREPIQASTAGEAIEKMLEQKKISSKINYNVLRDLNSKGSNTPKKEDDSTDDSTNTKKLSRRKSIASRNIASPVNSVGKRLRPLISTQLAKKAATEEVTFPNAPAEASNIEKPATVLVESGPVAYNLDEEVEEEEAEEEDDHCMSALQLMGGNDYGCDMDDDDGY", "length": 681, "header": "tr|F1NQ85-1|F1NQ85_CHICK Isoform 1 of Transcription factor IIIB 90 kDa subunit OS=Gallus gallus OX=9031 GN=BRF1 PE=3 SV=2 CANONICAL=F1NQ85-1" }, "isoforms": [ { "isoform_ac": "F1NQ85-1", "url": "https://www.uniprot.org/uniprotkb/F1NQ85/entry#F1NQ85-1", "sequence": { "sequence": "MPGGRVCAACGCSEIEVDAARGDAVCTGCGSVLEDNIIVSEVQFVENSGGGSSAVGQFVSLDGAGKTPTLGGGFHANLGKESRAQTLQNGKRQIHHLGNQLQLNQHCLDTAFNFFKMAVSKHLTRGRKMTHVIAACLYLVCRTEGTPHMLLDLSDLLQVNVYVLGKTFLLLARELCINAPAIDPCLYIPRFAHMLEFGDKNHEVSMTALRLLQRMKRDWMHTGRRPSGLCGAALLVAARMHDFRRTVKEVIRVVKVCESTLRKRLTEFEYTPTSQLTIDEFMRIDLEEECDPPSFTAGQKKLKIQQLEKALSKKLEDFEGEISSYQDEIEIELENSRPKAKGVFANLSKSDSIEDNTLSIFGEEEAEDEELEAAANHLNKDFCNELLEKDRLKPGEDGDCKNGNEAPVRPPALESLLGPLPTAASLGITESIKECISSKDREPGENTGDGELDLSGIDDSEIDRYILNETEAQIKAELWMKENADYLKEQKEKEARIAKEKELGIYKEHKPKKAAKKREPIQASTAGEAIEKMLEQKKISSKINYNVLRDLNSKGSNTPKKEDDSTDDSTNTKKLSRRKSIASRNIASPVNSVGKRLRPLISTQLAKKAATEEVTFPNAPAEASNIEKPATVLVESGPVAYNLDEEVEEEEAEEEDDHCMSALQLMGGNDYGCDMDDDDGY", "length": 681, "header": "tr|F1NQ85-1|F1NQ85_CHICK Isoform 1 of Transcription factor IIIB 90 kDa subunit OS=Gallus gallus OX=9031 GN=BRF1 PE=3 SV=2 CANONICAL=F1NQ85-1" }, "locus": { "chromosome": "5", "start_pos": 52340334, "end_pos": 52181227, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010041295.1", "url": "https://www.ensembl.org/id/ENSGALT00010041295.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024181.1", "url": "https://www.ensembl.org/id/ENSGALP00010024181.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-76061", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-76061", "resource": "Reactome", "description": "RNA Polymerase III Transcription Initiation From Type 1 Promoter" }, { "id": "R-GGA-76066", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-76066", "resource": "Reactome", "description": "RNA Polymerase III Transcription Initiation From Type 2 Promoter" } ], "orthologs": [ { "uniprot_canonical_ac": "A0ABK0LQE8-1", "protein_name": "Transcription factor IIIB 90 kDa subunit", "gene_name": "Brf1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTGRVCRGCGGTDIELDAARGDAVCTGCGSVLEDNIIVSEVQFVENSGGGSSAVGQFVSLDGAGKTPTLGGGFHVNLGKESRAQTLQNGRRHIHHLGSQLQLNQHCLDTAFNFFKMAVSKHLTRGRKMAHVIAACLYLVCRTEGTPHMLLDLSDLLQVNVYVLGKTFLLLARELCINAPAIDPCLYIPRFAHLLEFGEKNHEVSMTALRLLQRMKRDWMHTGRRPSGLCGAALLVAARMHDFRRTVKEVISVVKVCESTLRKRLTEFEDTPTSQLTIDEFMKIDLEEECDPPSYTAGQRKLRMKQLEQVLSKKLEEVEGEISTYQDAIEIELENSRPKAKGALANLSKDGSGEDATSSPFCEEDTEDEELEAAASHMNKDFYRELLGADGGSEAAEDADGGSRPLALESLLGPLPTAASLGISDSIRECISSPSGDPKDSSGDGELDLSGIDDLEIDRYILNESEARVKAELWMRENAEYLREQKEKEARIAKEKELGIYKEHKPKKSCKRREPILASTAGEAIEKMLEQKKISSKINYSVLRDLNSKGGGSPPRDDSQPPEHTSTKKLSRRKRAATRNSADPGTSMGKRLRPLVSAQPAKKAAVGEALLLNSPALGAEPVKPSAVLVESGPVSYHPEEDADEEDAEEEDGEPCVSALQMMGGNDYGCDGDEDDGY", "length": 676 }, "evidence": [ { "id": "F1NQ85", "url": "https://omabrowser.org/oma/group/F1NQ85/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3X7R9-1", "protein_name": "Transcription factor IIIB 90 kDa subunit", "gene_name": "BRF1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MTGRVCRGCGGTDIELDAARGDAVCTGCGSVLEDNIIVSEVQFVENSGGGSSAVGQFVSLDGAGKAPTLGGGFHVSLGKESRAQTLQNGRRQIHHLGNQLQLNQHCLDTAFNFFKMAVSKHLTRGRRTAHVVAACLYLVCRTEGTPHMLLDLSDLLQVNVYVLGKTFLLLARELCINAPAIDPCLYIPRFAHLLEFGEKNHEVSMTALRLLQRMKRDWMHTGRRPSGLCGAALLVAARMHDFRRTVKEVISVVKVCESTLRKRLTEFEDTPTSQLTVDEFMKIDLEEECDPPSYTAGQRKLRLKQLEQVLSKQLEAVEGEITTYQDAIEIELENSRPKAKGALASLTKDGSVEDSTSSLCGEEDTEDEELEAAASHLNKDFYQELLGGSVPGSSEAAGVPEEGRRPPALESLLGPLPTAASLGISDSIRECISSPSHEPKDACGDGELDLSGIDDLEIDRYILNEAEARVKAELWMRENAEYLREQKEKEARIAKERELGIYKEHKPKKSCKRREPIQASTAGEAIEKMLEQKKISSKINYSVLRGLDAGGGPPGEDGPPPREHGPPPGEDTGPQGEAARPPEWTSARRLSRRKTSSRRSRPDPSTSAGKRLRPLVSTQPAKKVALGEASLPSAHSLEAERVRPTVVVVESGPVSYHAEEDAEEEDAEEEDGEPCVSALQMMGGNDYGCDGDDDDGY", "length": 697 }, "evidence": [ { "id": "F1NQ85", "url": "https://omabrowser.org/oma/group/F1NQ85/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P29056-1", "protein_name": "Transcription factor IIIB 70 kDa subunit", "gene_name": "BRF1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MPVCKNCHGTEFERDLSNANNDLVCKACGVVSEDNPIVSEVTFGETSAGAAVVQGSFIGAGQSHAAFGGSSALESREATLNNARRKLRAVSYALHIPEYITDAAFQWYKLALANNFVQGRRSQNVIASCLYVACRKEKTHHMLIDFSSRLQVSVYSIGATFLKMVKKLHITELPLADPSLFIQHFAEKLDLADKKIKVVKDAVKLAQRMSKDWMFEGRRPAGIAGACILLACRMNNLRRTHTEIVAVSHVAEETLQQRLNEFKNTKAAKLSVQKFRENDVEDGEARPPSFVKNRKKERKIKDSLDKEEMFQTSEEALNKNPILTQVLGEQELSSKEVLFYLKQFSERRARVVERIKATNGIDGENIYHEGSENETRKRKLSEVSIQNEHVEGEDKETEGTEEKVKKVKTKTSEEKKENESGHFQDAIDGYSLETDPYCPRNLHLLPTTDTYLSKVSDDPDNLEDVDDEELNAHLLNEEASKLKERIWIGLNADFLLEQESKRLKQEADIATGNTSVKKKRTRRRNNTRSDEPTKTVDAAAAIGLMSDLQDKSGLHAALKAAEESGDFTTADSVKNMLQKASFSKKINYDAIDGLFR", "length": 596 }, "evidence": [ { "id": "F1NQ85", "url": "https://omabrowser.org/oma/group/F1NQ85/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q8CFK2-1", "protein_name": "Transcription factor IIIB 90 kDa subunit", "gene_name": "Brf1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTGRVCRGCGGTDIELDAARGDAVCTGCGSVLEDNIIVSEVQFVENSGGGSSAVGQFVSLDGAGKTPTLGGGFHVNLGKESRAQTLQNGRRHIHHLGSQLQLNQHCLDTAFNFFKMAVSKHLTRGRKMAHVIAACLYLVCRTEGTPHMLLDLSDLLQVNVYVLGKTFLLLARELCINAPAIDPCLYIPRFAHLLEFGEKNHEVSMTALRLLQRMKRDWMHTGRRPSGLCGAALLVAARMHDFRRTVKEVISVVKVCESTLRKRLTEFEDTPTSQLTIDEFMKIDLEEECDPPSYTAGQRKLRMKQLEQVLSKKLEEVEGEISSYQDAIEIELENSRPKAKGALANLSKDGSGEDATSSPRCEEDTEDEELEAAASHMNKDFYRELLGDDDGSEAAGDPDGGSRPLALESLLGPLPTAASLGISDSIRECISSPSGDPKDSSGDGELDLSGIDDLEIDRYILNESEARVKAELWMRENAEYLREQKEKEARIAKEKELGIYKEHKPKKSCKRREPILASTAGEAIEKMLEQKKISSKINYSVLRDLNSKGGGSPPRDDSQPPERASTKKLSRRKRATTRNSADPGTSTGKRLRPLLSAQPAKKAAVGEALLLSSPALGAEPVKPSAVLVESGPVPYHPEEDADEEDAEDEDGEPCVSALQMMGGNDYGCDGDEDDGY", "length": 676 }, "evidence": [ { "id": "F1NQ85", "url": "https://omabrowser.org/oma/group/F1NQ85/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q92994-1", "protein_name": "Transcription factor IIIB 90 kDa subunit", "gene_name": "BRF1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTGRVCRGCGGTDIELDAARGDAVCTACGSVLEDNIIVSEVQFVESSGGGSSAVGQFVSLDGAGKTPTLGGGFHVNLGKESRAQTLQNGRRHIHHLGNQLQLNQHCLDTAFNFFKMAVSRHLTRGRKMAHVIAACLYLVCRTEGTPHMLLDLSDLLQVNVYVLGKTFLLLARELCINAPAIDPCLYIPRFAHLLEFGEKNHEVSMTALRLLQRMKRDWMHTGRRPSGLCGAALLVAARMHDFRRTVKEVISVVKVCESTLRKRLTEFEDTPTSQLTIDEFMKIDLEEECDPPSYTAGQRKLRMKQLEQVLSKKLEEVEGEISSYQDAIEIELENSRPKAKGGLASLAKDGSTEDTASSLCGEEDTEDEELEAAASHLNKDLYRELLGGAPGSSEAAGSPEWGGRPPALGSLLDPLPTAASLGISDSIRECISSQSSDPKDASGDGELDLSGIDDLEIDRYILNESEARVKAELWMRENAEYLREQREKEARIAKEKELGIYKEHKPKKSCKRREPIQASTAREAIEKMLEQKKISSKINYSVLRGLSSAGGGSPHREDAQPEHSASARKLSRRRTPASRSGADPVTSVGKRLRPLVSTQPAKKVATGEALLPSSPTLGAEPARPQAVLVESGPVSYHADEEADEEEPDEEDGEPCVSALQMMGSNDYGCDGDEDDGY", "length": 677 }, "evidence": [ { "id": "F1NQ85", "url": "https://omabrowser.org/oma/group/F1NQ85/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VEL2-1", "protein_name": "B-related factor 1", "gene_name": "Brf", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSTGLKCRNCGSNEIEEDNARGDRVCMNCGSVLEDSLIVSEVQFEEVGHGAAAIGQFVSAESSGGATNYGYGKFQVGSGTESREVTIKKAKKDITLLCQQLQLSQHYADTALNFFKMALGRHLTRGRKSTHIYAACVYMTCRTEGTSHLLIDISDVQQICSYELGRTYLKLSHALCINIPSLDPCLYIMRFANRLQLGAKTHEVSMTALRIVQRMKKDCMHSGRRPTGLCGAALLIAARMHDFSRTMLDVIGVVKIHESTLRKRLSEFAETPSGGLTLEEFMTVDLEREQDPPSFKAARKKDRERIKDMGEHELTELQKEIDAHLEKDLGKYSNSVYRQLTKGKGLSPLSSPSTPNSSSEKDIELEESRQFIEQSNAEVIKELIAKNEDVKKSEPGGLVAGIEGLRPDIEAICRVTQSDLEDVEKAKQPQEQELITDDLNDDELDQYVLTEEESVAKLEMWKNLNAEYLQEQKERDERLAKEREEGKPERKKRKPRKKVIGPSSTAGEAIEKMLQEKKISSKINYEILKTLTDGMGGLTDDSPTTSADTKPSTLEELKHQPVIVEEGPVASKSRGNRAAYDLPGPSRKRPKLEVGLPVSKAADVEQAETKPAVVVEADDLDEDADDPDVEPEAEPEATLQDMLNTGGDDDEFGYGFDEEEEY", "length": 662 }, "evidence": [ { "id": "F1NQ85", "url": "https://omabrowser.org/oma/group/F1NQ85/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "transcription preinitiation complex", "id": "GO:0097550", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097550", "evidence": [ { "database": "UniProtKB", "id": "F1NQ85", "url": "https://www.uniprot.org/uniprotkb/F1NQ85" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1NQ85", "url": "https://www.uniprot.org/uniprotkb/F1NQ85" } ], "pmid": "" }, { "name": "transcription factor TFIIIB complex", "id": "GO:0000126", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000126", "evidence": [ { "database": "UniProtKB", "id": "F1NQ85", "url": "https://www.uniprot.org/uniprotkb/F1NQ85" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "F1NQ85", "url": "https://www.uniprot.org/uniprotkb/F1NQ85" } ], "pmid": "" }, { "name": "TBP-class protein binding", "id": "GO:0017025", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017025", "evidence": [ { "database": "UniProtKB", "id": "F1NQ85", "url": "https://www.uniprot.org/uniprotkb/F1NQ85" } ], "pmid": "" }, { "name": "RNA polymerase III type 3 promoter sequence-specific DNA binding", "id": "GO:0001006", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001006", "evidence": [ { "database": "UniProtKB", "id": "F1NQ85", "url": "https://www.uniprot.org/uniprotkb/F1NQ85" } ], "pmid": "" }, { "name": "RNA polymerase III general transcription initiation factor activity", "id": "GO:0000995", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000995", "evidence": [ { "database": "UniProtKB", "id": "F1NQ85", "url": "https://www.uniprot.org/uniprotkb/F1NQ85" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "transcription by RNA polymerase III", "id": "GO:0006383", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006383", "evidence": [ { "database": "UniProtKB", "id": "F1NQ85", "url": "https://www.uniprot.org/uniprotkb/F1NQ85" } ], "pmid": "" }, { "name": "DNA-templated transcription initiation", "id": "GO:0006352", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006352", "evidence": [ { "database": "UniProtKB", "id": "F1NQ85", "url": "https://www.uniprot.org/uniprotkb/F1NQ85" } ], "pmid": "" }, { "name": "transcription preinitiation complex assembly", "id": "GO:0070897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070897", "evidence": [ { "database": "UniProtKB", "id": "F1NQ85", "url": "https://www.uniprot.org/uniprotkb/F1NQ85" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 346, "end_pos": 348, "annotation": "n_glycosylation_sequon" }, { "start_pos": 468, "end_pos": 470, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1NQ85-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 681, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1NQ85-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1NQ85" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 346, "end_pos": 348 }, { "start_pos": 468, "end_pos": 470 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1NQE8-1", "uniprot_ac": "F1NQE8", "uniprot_id": "F1NQE8_CHICK", "mass": { "chemical_mass": 36993.0, "monoisotopic_mass": 36993.0 }, "refseq": { "ac": "NP_001026685", "name": "melanocortin receptor 4", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026685" }, "gene_names": [ { "name": "MC4R", "type": "recommended", "evidence": [ { "id": "F1NQE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NQE8" } ] }, { "name": "MC4R", "type": "synonym", "evidence": [ { "id": "NP_001026685", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026685" } ] } ], "protein_names": [ { "name": "Melanocortin receptor 4", "type": "recommended", "evidence": [ { "id": "F1NQE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NQE8/entry#names_and_taxonomy" } ] }, { "name": "melanocortin receptor 4", "type": "synonym", "evidence": [ { "id": "NP_001026685", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026685" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript is intronless :: HAEL01007110.1 [ECO:0000345] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000040.1. On Dec 14, 2021 this sequence version replaced NP_001026685.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001026685", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026685" } ] }, { "annotation": "A significant association between the MC4R genotype and body weight at 2, 4, and 10 wk of age was detected. Chickens possessing the BB genotype of CAPN1 showed significantly heavier body weight at 6 wk of age and guanine content at 4 wk of age, compared with those of the other genotypes. In addition, high expression levels of the CAPN1 and ADSL genes were detected in the breast muscle at 2 wk of age.", "evidence": [ { "database": "RefSeq", "id": "NP_001026685", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026685" }, { "database": "PubMed", "id": "31111951", "url": "https://glygen.org/publication/PubMed/31111951" } ] }, { "annotation": "Data preliminarily deduced that MC4R and POU1F1 gene were probably the major gene on growth performance or a QTL linked gene which associated with growth performance in chicken.", "evidence": [ { "database": "RefSeq", "id": "NP_001026685", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026685" }, { "database": "PubMed", "id": "18779134", "url": "https://glygen.org/publication/PubMed/18779134" } ] }, { "annotation": "Detailed functional studies on 4 cMC4R mutations, including Q18H, G21R, S76L, and L299P; cloned cMC4R complementary DNA (cDNA) and performed functional studies including expression, ligand binding, and signaling", "evidence": [ { "database": "RefSeq", "id": "NP_001026685", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026685" }, { "database": "PubMed", "id": "26521202", "url": "https://glygen.org/publication/PubMed/26521202" } ] }, { "annotation": "Major candidate gene for carcass traits such as body weight and growth.", "evidence": [ { "database": "RefSeq", "id": "NP_001026685", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026685" }, { "database": "PubMed", "id": "17312994", "url": "https://glygen.org/publication/PubMed/17312994" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NQE8", "url": "https://www.uniprot.org/uniprotkb/F1NQE8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MC4R", "url": "https://www.uniprot.org/uniprotkb/F1NQE8", "locus": { "chromosome": "2", "start_pos": 68795620, "end_pos": 68797456, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012132", "url": "https://www.ensembl.org/id/ENSGALG00010012132" } ] } } ], "crossref": [ { "id": "F1NQE8", "url": "https://alphafold.ebi.ac.uk/entry/F1NQE8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000012907", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000012907", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd15353", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15353", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "428485", "url": "https://www.ncbi.nlm.nih.gov/gene/428485", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000155", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000155", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001671", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001671", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001908", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001908", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:428485", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:428485", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "FYISCPH", "url": "https://omabrowser.org/oma/group/FYISCPH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1NQE8", "url": "https://www.orthodb.org/?gene=F1NQE8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22750", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22750", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00001", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00001", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-375276", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-375276", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-418555", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-418555", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001026685", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026685", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1NQE8", "url": "https://www.uniprot.org/uniprotkb/F1NQE8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NQE8-1", "url": "https://www.uniprot.org/uniprotkb/F1NQE8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNFTQHRGTLQPLHFWNHSNGLHRGASEPSAKGHSSGGCYEQLFVSPEVFVTLGIISLLENVLVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNNTDTDAQSFTINIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGVIITCIWAACTVSGILFIIYSDSSVVIICLISMFFTMLILMASLYVHMFMMARMHIKKIAVLPGTGPIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPYNPYCVCFMSHFNFYLILIMCNSIIDPLIYAFRSQELRKTFKEIICCCNLRGLCDLPGKY", "length": 331, "header": "tr|F1NQE8-1|F1NQE8_CHICK Isoform 1 of Melanocortin receptor 4 OS=Gallus gallus OX=9031 GN=MC4R PE=3 SV=1 CANONICAL=F1NQE8-1" }, "isoforms": [ { "isoform_ac": "F1NQE8-1", "url": "https://www.uniprot.org/uniprotkb/F1NQE8/entry#F1NQE8-1", "sequence": { "sequence": "MNFTQHRGTLQPLHFWNHSNGLHRGASEPSAKGHSSGGCYEQLFVSPEVFVTLGIISLLENVLVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNNTDTDAQSFTINIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGVIITCIWAACTVSGILFIIYSDSSVVIICLISMFFTMLILMASLYVHMFMMARMHIKKIAVLPGTGPIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPYNPYCVCFMSHFNFYLILIMCNSIIDPLIYAFRSQELRKTFKEIICCCNLRGLCDLPGKY", "length": 331, "header": "tr|F1NQE8-1|F1NQE8_CHICK Isoform 1 of Melanocortin receptor 4 OS=Gallus gallus OX=9031 GN=MC4R PE=3 SV=1 CANONICAL=F1NQE8-1" }, "locus": { "chromosome": "2", "start_pos": 68796952, "end_pos": 68795960, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029101.1", "url": "https://www.ensembl.org/id/ENSGALT00010029101.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016860.1", "url": "https://www.ensembl.org/id/ENSGALP00010016860.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The single nucleotide polymorphisms of chicken melanocortin-4 receptor (MC4R) gene and their association analysis with carcass traits.", "journal": "Science in China. Series C, Life sciences", "date": "2006-12", "authors": "Qiu Xuemei, Li Ning, Deng Xuemei, Zhao Xingbo, Meng Qingyong, Wang Xiuli", "evidence": [ { "database": "RefSeq", "id": "NP_001026685", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026685" } ], "reference": [ { "type": "PubMed", "id": "17312994", "url": "https://glygen.org/publication/PubMed/17312994" } ] }, { "title": "[Genetic effects of MC4R and POU1F1 gene on the growth performance in Jinghai yellow chicken].", "journal": "Yi chuan = Hereditas", "date": "2008-07", "authors": "Tao Yong, Li Guo-Hui, Hu Yu-Ping, Mekki M Dafalla, Chen Kuan-Wei, Wang Jin-Yu", "evidence": [ { "database": "RefSeq", "id": "NP_001026685", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026685" } ], "reference": [ { "type": "PubMed", "id": "18779134", "url": "https://glygen.org/publication/PubMed/18779134" } ] }, { "title": "Pharmacologic analyses of four chicken melanocortin-4 receptor mutations.", "journal": "Domestic animal endocrinology", "date": "2016-01", "authors": "Wang Z-Q, Huang J-S, Zhou J-H, Shi L, Jiang X-F, Tao Y-X", "evidence": [ { "database": "RefSeq", "id": "NP_001026685", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026685" } ], "reference": [ { "type": "PubMed", "id": "26521202", "url": "https://glygen.org/publication/PubMed/26521202" } ] }, { "title": "Effects of the MC4R, CAPN1, and ADSL genes on body weight and purine content in slow-growing chickens.", "journal": "Poultry science", "date": "2019-10-01", "authors": "Kubota Satoshi, Vandee Achiraya, Keawnakient Porntiwa, Molee Wittawat, Yongsawatdikul Jirawat, Molee Amonrat", "evidence": [ { "database": "RefSeq", "id": "NP_001026685", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026685" } ], "reference": [ { "type": "PubMed", "id": "31111951", "url": "https://glygen.org/publication/PubMed/31111951" } ] } ], "pathway": [ { "id": "gga:428485", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:428485", "resource": "KEGG Pathway" }, { "id": "R-GGA-375276", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-375276", "resource": "Reactome", "description": "Peptide ligand-binding receptors" }, { "id": "R-GGA-418555", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-418555", "resource": "Reactome", "description": "G alpha (s) signalling events" } ], "orthologs": [ { "uniprot_canonical_ac": "G3HMW1-1", "protein_name": "Melanocortin receptor 4", "gene_name": "Mc4r", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MNSTHHHGMYTSLHLWNRSSHGLQGNTSESPGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLVLMASLYVHMFLMARLHIKRIAVLPGTGTIRQGANMKGAITLTILIGVFVVCWAPFFLHLLFYISCPQNPYCVCFMSHFNLYLILIMCNAIIDPLIYALRSQELRKTFKEIICFYPLGGICDWSGRY", "length": 332 }, "evidence": [ { "id": "F1NQE8", "url": "https://omabrowser.org/oma/group/F1NQE8/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "O97504-1", "protein_name": "Melanocortin receptor 4", "gene_name": "MC4R", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MNSTHHHGMHTSLHFWNRSTYGLHSNASEPLGKGYSEGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAVCTVSGVLFIIYSDSSAVIICLITVFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGTIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY", "length": 332 }, "evidence": [ { "id": "F1NQE8", "url": "https://omabrowser.org/oma/group/F1NQE8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P32245-1", "protein_name": "Melanocortin receptor 4", "gene_name": "MC4R", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY", "length": 332 }, "evidence": [ { "id": "F1NQE8", "url": "https://omabrowser.org/oma/group/F1NQE8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P56450-1", "protein_name": "Melanocortin receptor 4", "gene_name": "Mc4r", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNSTHHHGMYTSLHLWNRSSYGLHGNASESLGKGHPDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVRRVGIIISCIWAACTVSGVLFIIYSDSSAVIICLISMFFTMLVLMASLYVHMFLMARLHIKRIAVLPGTGTIRQGTNMKGAITLTILIGVFVVCWAPFFLHLLFYISCPQNPYCVCFMSHFNLYLILIMCNAVIDPLIYALRSQELRKTFKEIICFYPLGGICELSSRY", "length": 332 }, "evidence": [ { "id": "F1NQE8", "url": "https://omabrowser.org/oma/group/F1NQE8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P70596-1", "protein_name": "Melanocortin receptor 4", "gene_name": "Mc4r", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MNSTHHHGMYTSLHLWNRSSHGLHGNASESLGKGHSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVRRVGIIISCIWAACTVSGVLFIIYSDSSAVIICLITMFFTMLVLMASLYVHMFLMARLHIKRIAVLPGTGTIRQGANMKGAITLTILIGVFVVCWAPFFLHLLFYISCPQNPYCVCFMSHFNLYLILIMCNAVIDPLIYALRSQELRKTFKEIICFYPLGGICELPGRY", "length": 332 }, "evidence": [ { "id": "F1NQE8", "url": "https://omabrowser.org/oma/group/F1NQE8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9GLJ8-1", "protein_name": "Melanocortin receptor 4", "gene_name": "MC4R", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MNSTQPLGMHTSLHSWNRSAHGMPTNVSESLAKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVDIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVAITISAIWAACTVSGVLFIIYSDSSAVIICLITVFFTMLALMASLYVHMFLMARLHIKRIAVLPGSGTIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCSPLGGLCDLSSRY", "length": 332 }, "evidence": [ { "id": "F1NQE8", "url": "https://omabrowser.org/oma/group/F1NQE8/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1NQE8", "url": "https://www.uniprot.org/uniprotkb/F1NQE8" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F1NQE8", "url": 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"snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 107, "end_pos": 109 }, { "start_pos": 17, "end_pos": 19 }, { "start_pos": 2, "end_pos": 4 }, { "start_pos": 96, "end_pos": 98 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 4 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "F1NQG5-1", "uniprot_ac": "F1NQG5", "uniprot_id": "F1NQG5_CHICK", "mass": { "chemical_mass": 24132.0, "monoisotopic_mass": 24132.0 }, "refseq": { "ac": "NP_001292094", "name": "large ribosomal subunit protein eL15", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001292094" }, "gene_names": [ { "name": "RPL15", "type": "recommended", "evidence": [ { "id": "F1NQG5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NQG5" } ] }, { "name": "L10", "type": "synonym", "evidence": [ { "id": "NP_001292094", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001292094" } ] }, { "name": "RPL15", "type": "synonym", "evidence": [ { "id": "NP_001292094", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001292094" } ] } ], "protein_names": [ { "name": "Ribosomal protein L15", "type": "recommended", "evidence": [ { "id": "F1NQG5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NQG5/entry#names_and_taxonomy" } ] }, { "name": "60S ribosomal protein L15", "type": "synonym", "evidence": [ { "id": "NP_001292094", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001292094" } ] }, { "name": "L10 ribosomal protein", "type": "synonym", "evidence": [ { "id": "NP_001292094", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001292094" } ] }, { "name": "large ribosomal subunit protein eL15", "type": "synonym", "evidence": [ { "id": "NP_001292094", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001292094" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: BU357024.1, DR411243.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BU357024.1, BU136896.1, BX279156.4 and BU410568.1. On Feb 26, 2015 this sequence version replaced XP_426002.2. Sequence Note: This RefSeq record was created from transcript data from different strains because no single transcript from the same strain was available for the full length of the gene. The extent of this transcript is supported by transcript alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001292094", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001292094" } ] }, { "annotation": "Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.", "evidence": [ { "database": "UniProtKB", "id": "F1NQG5", "url": "https://www.uniprot.org/uniprotkb/F1NQG5#function" }, { "database": "UniProtKB", "id": "ARBA00034092", "url": "https://www.uniprot.org/uniprotkb/ARBA00034092#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NQG5", "url": "https://www.uniprot.org/uniprotkb/F1NQG5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RPL15", "url": "https://www.uniprot.org/uniprotkb/F1NQG5", "locus": { "chromosome": "2", "start_pos": 37101698, "end_pos": 37093485, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010001698", "url": "https://www.ensembl.org/id/ENSGALG00010001698" } ] } } ], "crossref": [ { "id": "F1NQG5", "url": "https://alphafold.ebi.ac.uk/entry/F1NQG5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000011290", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000011290", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "428442", "url": "https://www.ncbi.nlm.nih.gov/gene/428442", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "8Q7Z", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=8Q7Z&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "8Q87", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=8Q87&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "IPR000439", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000439", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012678", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012678", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020925", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020925", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024794", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024794", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:428442", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:428442", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YIRDAWK", "url": "https://omabrowser.org/oma/group/YIRDAWK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1NQG5", "url": "https://www.orthodb.org/?gene=F1NQG5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11847", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11847", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11847:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11847:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "pdb_00008q7z", "url": "https://www.rcsb.org/structure/pdb_00008q7z", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00008q87", "url": "https://www.rcsb.org/structure/pdb_00008q87", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "8Q7Z", "url": "https://www.rcsb.org/structure/8Q7Z", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "8Q87", "url": "https://www.rcsb.org/structure/8Q87", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "PF00827", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00827", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-1799339", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1799339", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-72706", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-72706", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-975956", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-975956", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-975957", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-975957", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9954709", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9954709", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9954714", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9954714", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9954716", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9954716", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001292094", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001292094", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1NQG5", "url": "https://www.uniprot.org/uniprotkb/F1NQG5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NQG5-1", "url": "https://www.uniprot.org/uniprotkb/F1NQG5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGAYKYIQELWRKKQSDVMRFLLRVRCWQYRQLSALHRAPRPTRPDKARRLGYKAKQGYVIYRVRVRRGGRKRPVPKGATYGKPVHHGVNQLKFARSLQSVAEERAGRHCGALRVLNSYWVGEDSTYKFFEVILIDPFHKAIRRNPDTQWITKPVHKHREMRGLTSAGRKSRGLGKGHKFHHTIGGSRRAAWRRRNTLQLHRYR", "length": 204, "header": "tr|F1NQG5-1|F1NQG5_CHICK Isoform 1 of Ribosomal protein L15 OS=Gallus gallus OX=9031 GN=RPL15 PE=1 SV=2 CANONICAL=F1NQG5-1" }, "isoforms": [ { "isoform_ac": "F1NQG5-1", "url": "https://www.uniprot.org/uniprotkb/F1NQG5/entry#F1NQG5-1", "sequence": { "sequence": "MGAYKYIQELWRKKQSDVMRFLLRVRCWQYRQLSALHRAPRPTRPDKARRLGYKAKQGYVIYRVRVRRGGRKRPVPKGATYGKPVHHGVNQLKFARSLQSVAEERAGRHCGALRVLNSYWVGEDSTYKFFEVILIDPFHKAIRRNPDTQWITKPVHKHREMRGLTSAGRKSRGLGKGHKFHHTIGGSRRAAWRRRNTLQLHRYR", "length": 204, "header": "tr|F1NQG5-1|F1NQG5_CHICK Isoform 1 of Ribosomal protein L15 OS=Gallus gallus OX=9031 GN=RPL15 PE=1 SV=2 CANONICAL=F1NQG5-1" }, "locus": { "chromosome": "2", "start_pos": 37098138, "end_pos": 37094678, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010003897.1", "url": "https://www.ensembl.org/id/ENSGALT00010003897.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010002201.1", "url": "https://www.ensembl.org/id/ENSGALP00010002201.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Cryo-EM structure of the inactive ribosome complex accumulated in chick embryo cells in cold-stress conditions.", "journal": "FEBS Lett.", "date": "2024", "authors": "Nurullina Liliia, Terrosu Salvatore, Myasnikov Alexander G, Jenner Lasse Bohl, Yusupov Marat", "evidence": [ { "database": "UniProtKB", "id": "F1NQG5", "url": "https://www.uniprot.org/uniprotkb/F1NQG5" } ], "reference": [ { "type": "PubMed", "id": "38395592", "url": "https://glygen.org/publication/PubMed/38395592" } ] } ], "pathway": [ { "id": "gga:428442", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:428442", "resource": "KEGG Pathway" }, { "id": "R-GGA-1799339", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1799339", "resource": "Reactome", "description": "SRP-dependent cotranslational protein targeting to membrane" }, { "id": "R-GGA-72706", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-72706", "resource": "Reactome", "description": "GTP hydrolysis and joining of the 60S ribosomal subunit" }, { "id": "R-GGA-975956", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-975956", "resource": "Reactome", "description": "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" }, { "id": "R-GGA-975957", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-975957", "resource": "Reactome", "description": "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" }, { "id": "R-GGA-9954709", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9954709", "resource": "Reactome", "description": "Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide" }, { "id": "R-GGA-9954714", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9954714", "resource": "Reactome", "description": "PELO:HBS1L and ABCE1 dissociate a ribosome on a non-stop mRNA" }, { "id": "R-GGA-9954716", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9954716", "resource": "Reactome", "description": "ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA" } ], "orthologs": [ { "uniprot_canonical_ac": "G3H1F4-1", "protein_name": "Ribosomal protein L15", "gene_name": "Rpl15", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MGAYKYIQELWRKKQSDVMRFLLRVRCWQYRQLSALHRAPRPTRPDKARRLGYKAKQGYVIYRIRVRRGGRKRPVPKGATYGKPVHHGVNQLKFARSLQSVAEERAGRHCGALRVLNSYWVGEDSTYKFFEVILIDPFHKAIRRNPDTQWITKPVHKHREMRGLTSAGRKSRGLGKGHKFHHTIGGSRRAAWRRRNTLQLHRYR", "length": 204 }, "evidence": [ { "id": "F1NQG5", "url": "https://omabrowser.org/oma/group/F1NQG5/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "O17445-1", "protein_name": "Large ribosomal subunit protein eL15", "gene_name": "RpL15", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MGAYRYMQELYRKKQSDVMRYLLRIRVWQYRQLTKLHRSPRPTRPDKARRLGYRAKQGFVIYRIRVRRGGRKRPVPKGCTYGKPKSHGVNQLKPYRGLQSIAEERVGRRLGGLRVLNSYWIAQDASYKYFEVILIDTHHSAIRRDPKINWICKHVHKHRELRGLTSAGKSSRGIGKGYRYSQTIGGSRRAAWKRKNREHMHRKR", "length": 204 }, "evidence": [ { "id": "F1NQG5", "url": "https://omabrowser.org/oma/group/F1NQG5/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "O23515-1", "protein_name": "Large ribosomal subunit protein eL15z", "gene_name": "RPL15A", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MGAYKYVSELWRKKQSDVMRFLQRVRCWEYRQQPSIVRLVRPTRPDKARRLGYKAKQGFVVYRVRVRRGGRKRPVPKGIVYGKPTNQGVTQLKFQRSKRSVAEERAGRKLGGLRVVNSYWLNEDSTYKYYEIILVDPAHNAVRNDPRINWICNPVHKHRELRGLTSEGKKNRGLRGKGHNNHKNRPSRRATWKKNNSLSLRRYR", "length": 204 }, "evidence": [ { "id": "F1NQG5", "url": "https://omabrowser.org/oma/group/F1NQG5/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "P05748-1", "protein_name": "Large ribosomal subunit protein eL15A", "gene_name": "RPL15A", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MGAYKYLEELQRKKQSDVLRFLQRVRVWEYRQKNVIHRAARPTRPDKARRLGYKAKQGFVIYRVRVRRGNRKRPVPKGATYGKPTNQGVNELKYQRSLRATAEERVGRRAANLRVLNSYWVNQDSTYKYFEVILVDPQHKAIRRDARYNWICDPVHKHREARGLTATGKKSRGINKGHKFNNTKAGRRKTWKRQNTLSLWRYRK", "length": 204 }, "evidence": [ { "id": "F1NQG5", "url": "https://omabrowser.org/oma/group/F1NQG5/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P61313-1", "protein_name": "Large ribosomal subunit protein eL15", "gene_name": "RPL15", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGAYKYIQELWRKKQSDVMRFLLRVRCWQYRQLSALHRAPRPTRPDKARRLGYKAKQGYVIYRIRVRRGGRKRPVPKGATYGKPVHHGVNQLKFARSLQSVAEERAGRHCGALRVLNSYWVGEDSTYKFFEVILIDPFHKAIRRNPDTQWITKPVHKHREMRGLTSAGRKSRGLGKGHKFHHTIGGSRRAAWRRRNTLQLHRYR", "length": 204 }, "evidence": [ { "id": "F1NQG5", "url": "https://omabrowser.org/oma/group/F1NQG5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P61314-1", "protein_name": "Large ribosomal subunit protein eL15", "gene_name": "Rpl15", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGAYKYIQELWRKKQSDVMRFLLRVRCWQYRQLSALHRAPRPTRPDKARRLGYKAKQGYVIYRIRVRRGGRKRPVPKGATYGKPVHHGVNQLKFARSLQSVAEERAGRHCGALRVLNSYWVGEDSTYKFFEVILIDPFHKAIRRNPDTQWITKPVHKHREMRGLTSAGRKSRGLGKGHKFHHTIGGSRRAAWRRRNTLQLHRYR", "length": 204 }, "evidence": [ { "id": "F1NQG5", "url": "https://omabrowser.org/oma/group/F1NQG5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5EAD6-1", "protein_name": "Large ribosomal subunit protein eL15", "gene_name": "RPL15", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGAYKYIQELWRKKQSDVMRFLLRVRCWQYRQLSALHRAPRPTRPDKARRLGYKAKQGYVIYRIRVRRGGRKRPVPKGATYGKPVHHGVNQLKFARSLQSVAEERAGRHCGALRVLNSYWVGEDSTYKFFEVILIDPFHKAIRRNPDTQWITKPVHKHREMRGLTSAGRKSRGLGKGHKFHHTIGGSRRAAWRRRNTLQLHRYR", "length": 204 }, "evidence": [ { "id": "F1NQG5", "url": "https://omabrowser.org/oma/group/F1NQG5/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q86K01-1", "protein_name": "Large ribosomal subunit protein eL15", "gene_name": "rpl15-2", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MGAYKYLQELYKKKQSDAVRFLLRVRCWEYRNLPVCHRASHPTRVDKARRLGYKATQGFVVYRIRVRRGGRKRQVPGGRTGGKPKTHGVNELKPSRNLRSVAEERVGRRCPNLRVLNSYWVNQDSTYKYYEVILVDNSHNAIRNDPRYNWICKPVHKHRELRGLTSAGIKARGLRRKGTHRASKTRPSRQANYKRRNTVVFHRYR", "length": 205 }, "evidence": [ { "id": "F1NQG5", "url": "https://omabrowser.org/oma/group/F1NQG5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q9CZM2-1", "protein_name": "Large ribosomal subunit protein eL15", "gene_name": "Rpl15", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGAYKYIQELWRKKQSDVMRFLLRVRCWQYRQLSALHRAPRPTRPDKARRLGYKAKQGYVIYRIRVRRGGRKRPVPKGATYGKPVHHGVNQLKFARSLQSVAEERAGRHCGALRVLNSYWVGEDSTYKFFEVILIDPFHKAIRRNPDTQWITKPVHKHREMRGLTSAGRKSRGLGKGHKFHHTIGGSRRAAWRRRNTLQLHRYR", "length": 204 }, "evidence": [ { "id": "F1NQG5", "url": "https://omabrowser.org/oma/group/F1NQG5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "F1NQG5", "url": "https://www.uniprot.org/uniprotkb/F1NQG5" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "F1NQG5", "url": "https://www.uniprot.org/uniprotkb/F1NQG5" } ], "pmid": "" }, { "name": "structural constituent of ribosome", "id": "GO:0003735", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003735", "evidence": [ { "database": "UniProtKB", "id": "F1NQG5", "url": "https://www.uniprot.org/uniprotkb/F1NQG5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1NQG5", "url": "https://www.uniprot.org/uniprotkb/F1NQG5" } ], "pmid": "" }, { "name": "synapse", "id": "GO:0045202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045202", "evidence": [ { "database": "UniProtKB", "id": "F1NQG5", "url": "https://www.uniprot.org/uniprotkb/F1NQG5" } ], "pmid": "" }, { "name": "cytosolic large ribosomal subunit", "id": "GO:0022625", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022625", "evidence": [ { "database": "UniProtKB", "id": "F1NQG5", "url": "https://www.uniprot.org/uniprotkb/F1NQG5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "cytoplasmic translation", "id": "GO:0002181", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002181", "evidence": [ { "database": "UniProtKB", "id": "F1NQG5", "url": "https://www.uniprot.org/uniprotkb/F1NQG5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1NQG5-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 204, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1NQG5-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1NQG5" } ], "lectin_list": [], "domain_list": [], "binding_sites": [ { "evidence": [ { "id": "F1NQG5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NQG5#function" }, { "id": "F1NQG5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NQG5" }, { "id": "8Q87", "database": "PDB", "url": "https://www.rcsb.org/structure/8Q87" }, { "id": "8Q7Z", "database": "PDB", "url": "https://www.rcsb.org/structure/8Q7Z" } ], "binding_site_uniprot": 175, "amino_acid": "Gly", "chebi_lig_id": "CHEBI_18420", "ligand": "Mg(2+)", "ligand_label": "2", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0007829", "start_pos": 175, "end_pos": 175, "start_aa": "Gly", "end_aa": "Gly", "glycosite_overlap": "" }, { "evidence": [ { "id": "F1NQG5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NQG5#function" }, { "id": "F1NQG5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NQG5" }, { "id": "8Q87", "database": "PDB", "url": "https://www.rcsb.org/structure/8Q87" }, { "id": "8Q7Z", "database": "PDB", "url": "https://www.rcsb.org/structure/8Q7Z" } ], "binding_site_uniprot": 180, "amino_acid": "Phe", "chebi_lig_id": "CHEBI_18420", "ligand": "Mg(2+)", "ligand_label": "2", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0007829", "start_pos": 180, "end_pos": 180, "start_aa": "Phe", "end_aa": "Phe", "glycosite_overlap": "" }, { "evidence": [ { "id": "F1NQG5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NQG5#function" }, { "id": "F1NQG5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NQG5" }, { "id": "8Q7Z", "database": "PDB", "url": "https://www.rcsb.org/structure/8Q7Z" } ], "binding_site_uniprot": 203, "amino_acid": "Tyr", "chebi_lig_id": "CHEBI_18420", "ligand": "Mg(2+)", "ligand_label": "3", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0007829", "start_pos": 203, "end_pos": 203, "start_aa": "Tyr", "end_aa": "Tyr", "glycosite_overlap": "" }, { "evidence": [ { "id": "F1NQG5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NQG5#function" }, { "id": "F1NQG5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NQG5" }, { "id": "8Q87", "database": "PDB", "url": "https://www.rcsb.org/structure/8Q87" }, { "id": "8Q7Z", "database": "PDB", "url": "https://www.rcsb.org/structure/8Q7Z" } ], "binding_site_uniprot": 70, "amino_acid": "Gly", "chebi_lig_id": "CHEBI_18420", "ligand": "Mg(2+)", "ligand_label": "1", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0007829", "start_pos": 70, "end_pos": 70, "start_aa": "Gly", "end_aa": "Gly", "glycosite_overlap": "" } ], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "F1NQJ0-1", "uniprot_ac": "F1NQJ0", "uniprot_id": "F1NQJ0_CHICK", "mass": { "chemical_mass": 47574.0, "monoisotopic_mass": 47574.0 }, "refseq": { "ac": "XP_015147853", "name": "dipeptidase 2 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015147853" }, "gene_names": [ { "name": "DPEP2", "type": "recommended", "evidence": [ { "id": "F1NQJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NQJ0" } ] }, { "name": "DPEP2", "type": "synonym", "evidence": [ { "id": "XP_015147853", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015147853" } ] }, { "name": "DPEP3", "type": "synonym", "evidence": [ { "id": "XP_015147853", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015147853" } ] } ], "protein_names": [ { "name": "Dipeptidase", "type": "recommended", "evidence": [ { "id": "F1NQJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NQJ0/entry#names_and_taxonomy" } ] }, { "name": "3.4.13.19", "type": "synonym", "evidence": [ { "id": "F1NQJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NQJ0/entry#names_and_taxonomy" } ] }, { "name": "dipeptidase 2 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015147853", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015147853" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052542.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015147853", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015147853" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NQJ0", "url": "https://www.uniprot.org/uniprotkb/F1NQJ0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "DPEP2", "url": "https://www.uniprot.org/uniprotkb/F1NQJ0", "locus": { "chromosome": "11", "start_pos": 3118498, "end_pos": 3103192, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010025325", "url": "https://www.ensembl.org/id/ENSGALG00010025325" } ] } } ], "crossref": [ { "id": "F1NQJ0", "url": "https://alphafold.ebi.ac.uk/entry/F1NQJ0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000003433", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000003433", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd01301", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01301", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "107054267", "url": "https://www.ncbi.nlm.nih.gov/gene/107054267", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000180", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000180", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008257", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008257", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032466", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032466", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:107054267", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:107054267", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "SRHNVFG", "url": "https://omabrowser.org/oma/group/SRHNVFG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A2D7", "url": "https://www.orthodb.org/?gene=A0A8V1A2D7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NQJ0", "url": "https://www.orthodb.org/?gene=F1NQJ0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10443", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10443", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10443:SF9", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10443:SF9", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01244", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01244", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-2142691", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2142691", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-5423646", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5423646", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_015147853", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015147853", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "48940", "url": "https://www.rhea-db.org/rhea/48940", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V1A2D7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2D7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A2D7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2D7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NQJ0", "url": "https://www.uniprot.org/uniprotkb/F1NQJ0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NQJ0-1", "url": "https://www.uniprot.org/uniprotkb/F1NQJ0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKQNPTKLLLLMLMFLFDTVPFICEKSMRERAINLMEDTRLIDGHNDFVLRLRMFYQNRISKVNLREINKTHTNLLKLKAGYVGAQFWSVYVLCSAQNKDAVRLTLEQIDVVKRMCNSYEELELVTTSQGISDSRKIACLIGIEGGHSIDSSLAALRMYYDLGVRYMTLTHSCNTPWSESSSKGIHNFYPNVTGLTEFGQEVVKEMNRLGMLIDLSHTSYSTAKTALRISKAPVIFSHSSAFSVCNHSRNVPDDILQKLKKNKGIIMVTFNADVLACGRKVVNVSTLADHFDHIKRIAGSESIGIGGDYDGVERFPEGLEDVSKYPSLIEELLRRGWNETELKGVLKENFLRVFREVENVRKISRAMDVGESEIPHEEVQNSCRLDLHNIQIQPDRSFGFPSMAQSFSLTIVFVPYLIL", "length": 419, "header": "tr|F1NQJ0-1|F1NQJ0_CHICK Isoform 1 of Dipeptidase OS=Gallus gallus OX=9031 GN=DPEP2 PE=3 SV=2 CANONICAL=F1NQJ0-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A2D7-1", "url": "https://www.uniprot.org/uniprotkb/F1NQJ0/entry#A0A8V1A2D7-1", "sequence": { "sequence": "MWELSAQNKDAVRLTLEQIDVVKRMCNSYEELELVTTSQGISDSRKIACLIGIEGGHSIDSSLAALRMYYDLGVRYMTLTHSCNTPWSESSSKGIHNFYPNVTGLTEFGQEVVKEMNRLGMLIDLSHTSYSTAKTALRISKAPVIFSHSSAFSVCNHSRNVPDDILQKLKKNKGIIMVTFNADVLACGRKVVNVSTLADHFDHIKRIAGSESIGIGGDYDGVERFPEGLEDVSKYPSLIEELLRRGWNETELKGVLKENFLRVFREVENVRKISRAMDVGESEIPHEEVQNSCRLDLHNIQIQPDRSFGFPSMAQSFSLTIVFVPYLIL", "length": 329, "header": "tr|A0A8V1A2D7-1|A0A8V1A2D7_CHICK Computationally mapped isoform of Dipeptidase OS=Gallus gallus OX=9031 GN=DPEP2 PE=3 SV=1 CANONICAL=F1NQJ0-1" }, "locus": { "chromosome": "11", "start_pos": 3116952, "end_pos": 3109788, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010061821.1", "url": "https://www.ensembl.org/id/ENSGALT00010061821.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038160.1", "url": "https://www.ensembl.org/id/ENSGALP00010038160.1" } ] } }, { "isoform_ac": "F1NQJ0-1", "url": "https://www.uniprot.org/uniprotkb/F1NQJ0/entry#F1NQJ0-1", "sequence": { "sequence": "MKQNPTKLLLLMLMFLFDTVPFICEKSMRERAINLMEDTRLIDGHNDFVLRLRMFYQNRISKVNLREINKTHTNLLKLKAGYVGAQFWSVYVLCSAQNKDAVRLTLEQIDVVKRMCNSYEELELVTTSQGISDSRKIACLIGIEGGHSIDSSLAALRMYYDLGVRYMTLTHSCNTPWSESSSKGIHNFYPNVTGLTEFGQEVVKEMNRLGMLIDLSHTSYSTAKTALRISKAPVIFSHSSAFSVCNHSRNVPDDILQKLKKNKGIIMVTFNADVLACGRKVVNVSTLADHFDHIKRIAGSESIGIGGDYDGVERFPEGLEDVSKYPSLIEELLRRGWNETELKGVLKENFLRVFREVENVRKISRAMDVGESEIPHEEVQNSCRLDLHNIQIQPDRSFGFPSMAQSFSLTIVFVPYLIL", "length": 419, "header": "tr|F1NQJ0-1|F1NQJ0_CHICK Isoform 1 of Dipeptidase OS=Gallus gallus OX=9031 GN=DPEP2 PE=3 SV=2 CANONICAL=F1NQJ0-1" }, "locus": { "chromosome": "11", "start_pos": 3116952, "end_pos": 3108833, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010061826.1", "url": "https://www.ensembl.org/id/ENSGALT00010061826.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038163.1", "url": "https://www.ensembl.org/id/ENSGALP00010038163.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "gga:107054267", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:107054267", "resource": "KEGG Pathway" }, { "id": "R-GGA-2142691", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2142691", "resource": "Reactome", "description": "Synthesis of Leukotrienes (LT) and Eoxins (EX)" }, { "id": "R-GGA-5423646", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5423646", "resource": "Reactome", "description": "Aflatoxin activation and detoxification" } ], "orthologs": [ { "uniprot_canonical_ac": "A0AB32TYD9-1", "protein_name": "Dipeptidase", "gene_name": "dpep2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MWIPYKPPKTSFLSGPSFIFVFTKYILNLVDITKSEYEKSLCLKKVQSSQSQSTEGGDVSPRAFKLRHNACKTHWHLKFPHRKTECEPLHVHEYITPVFFQTRHNDWALHLRKHDDNKLTKVNLYNYPQGATDITRLIAGHVGGQVFSAYVLCTAQDKDAVRLTLEQIDVIRRMCTEKPELELVTTSEGMKKSTKIACLISVEGGHSIDSSLAALRMFYQLGVRSMSLTHTCNTPWAKSSSSFYQHYQWVNNSLTEFGKEVVHEMNRLGMLVDLSHSSWETARAVLKHTAAPVIFSHSSAYAVCNNVRNVPDDLLLLLKRNGGLIMVNLYNNFIACSSNKANVSIVADHFDHIKRVIGAESIGIGADYDGAQGFPEGLEDVSKYPALIEELIARNWTEQELAGVLRLNFLKVFEMVEKIRDDMLDTSPSEVEIPFLEANNSCRAMLIHPTKVSKMVKNGNAPQTMPAGAFAWFILFLIQSI", "length": 481 }, "evidence": [ { "id": "F1NQJ0", "url": "https://omabrowser.org/oma/group/F1NQJ0/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q5U2X4-1", "protein_name": "Dipeptidase 3", "gene_name": "Dpep3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQPTGPEGPRALSLRPLGHRLSLLGVLLIIPSLWVTCNQTTPSLSSAPTSPGASSAMTTPGIPNDTTTSGVTSDPRLREQALALMRDFPLVDGHNDLPLLLRELFQNKLQDVNLHNFTRGQTSLDRLRDGLVGAQFWSAYIPCQTQDRDAVRVALEQIDLIRRMCSAYPELELVTSADGLNSTQKLACLIGLEGGHSLDTSLAVLRSFYELGVRYLTLTFTCSTPWAESATKFRHHFYTNISGLTSFGEKVVEEMNRIGMMIDLSHASDTLVKQTLEASRAPVIFSHSAARSVCDNLLNVPDDILQLLKKNGGIVMVTLSMGVLQCSLLANVSTVADHFDHIRTVIGSEFIGIGGSYDGSGRFPQGLEDVSTYPVLLEELLRRGWGEQELQGVLRGNLLRVFRQVEQVREKSLGQSPVEVVFPERQQSSTCHSHLLPQSQDAHLKVTKLPSSQVLQRASKAPPCPLLGLVAAVTSPAFTLWLCCSGHR", "length": 488 }, "evidence": [ { "id": "F1NQJ0", "url": "https://omabrowser.org/oma/group/F1NQJ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9DA79-1", "protein_name": "Dipeptidase 3", "gene_name": "Dpep3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MQPAGLEGPRALGLRPLGHRLSLLGVLLLVPSLWVTCTLTTPSPSSAPTTPEASNATTAPGIPNDTATSGVTSDPRLREQALALMRDFPLVDGHNDLPLLLRELFQNQLQDVNLRNFTRGQTNLDRLRDGLVGAQFWSAYIPCQTQDRDAVRLALEQIDLIRRMCSAYPELELVTSADGLNNTQKLACLIGVEGGHSLDTSLAVLRSFYELGVRYLTLTFTCSTPWAESATKFRHHFYTNISGLTSFGEKVVEEMNRLGMMIDLSHASDTLVKQTLEVSQAPVIFSHSAARSVCDNLLNIPDDILQLLKKNGGIVMVTLSMGVLQCSLFANVSTVADHFDHIRTVIGSEFIGIGGSYDGSGRFPQGLEDVSTYPVLIEELLSRGWDERELQGVLRGNLLRVFRQVEQVREKSLGQSPVEVKFPERQQSNTCHSHLLPQPQEDQHQDTHLKVTKLPNILQRASKAPPHPLPGLMATLTSLALILWLCCSGHRAV", "length": 493 }, "evidence": [ { "id": "F1NQJ0", "url": "https://omabrowser.org/oma/group/F1NQJ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9H4B8-1", "protein_name": "Dipeptidase 3", "gene_name": "DPEP3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MQPTGREGSRALSRRYLRRLLLLLLLLLLRQPVTRAETTPGAPRALSTLGSPSLFTTPGVPSALTTPGLTTPGTPKTLDLRGRAQALMRSFPLVDGHNDLPQVLRQRYKNVLQDVNLRNFSHGQTSLDRLRDGLVGAQFWSASVSCQSQDQTAVRLALEQIDLIHRMCASYSELELVTSAEGLNSSQKLACLIGVEGGHSLDSSLSVLRSFYVLGVRYLTLTFTCSTPWAESSTKFRHHMYTNVSGLTSFGEKVVEELNRLGMMIDLSYASDTLIRRVLEVSQAPVIFSHSAARAVCDNLLNVPDDILQLLKKNGGIVMVTLSMGVLQCNLLANVSTVADHFDHIRAVIGSEFIGIGGNYDGTGRFPQGLEDVSTYPVLIEELLSRSWSEEELQGVLRGNLLRVFRQVEKVREESRAQSPVEAEFPYGQLSTSCHSHLVPQNGHQATHLEVTKQPTNRVPWRSSNASPYLVPGLVAAATIPTFTQWLC", "length": 488 }, "evidence": [ { "id": "F1NQJ0", "url": "https://omabrowser.org/oma/group/F1NQJ0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F1NQJ0", "url": "https://www.uniprot.org/uniprotkb/F1NQJ0" } ], "pmid": "" }, { "name": "side of membrane", "id": "GO:0098552", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098552", "evidence": [ { "database": "UniProtKB", "id": "F1NQJ0", "url": "https://www.uniprot.org/uniprotkb/F1NQJ0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "F1NQJ0", "url": "https://www.uniprot.org/uniprotkb/F1NQJ0" } ], "pmid": "" }, { "name": "leukotriene D4 catabolic process", "id": "GO:1901749", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901749", "evidence": [ { "database": "UniProtKB", "id": "F1NQJ0", "url": "https://www.uniprot.org/uniprotkb/F1NQJ0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "F1NQJ0", "url": "https://www.uniprot.org/uniprotkb/F1NQJ0" } ], "pmid": "" }, { "name": "metallodipeptidase activity", "id": "GO:0070573", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070573", "evidence": [ { "database": "UniProtKB", "id": "F1NQJ0", "url": "https://www.uniprot.org/uniprotkb/F1NQJ0" } ], "pmid": "" }, { "name": "dipeptidase activity", "id": "GO:0016805", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016805", "evidence": [ { "database": "UniProtKB", "id": "F1NQJ0", "url": "https://www.uniprot.org/uniprotkb/F1NQJ0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 191, "end_pos": 193, "annotation": "n_glycosylation_sequon" }, { "start_pos": 246, "end_pos": 248, "annotation": "n_glycosylation_sequon" }, { "start_pos": 283, "end_pos": 285, "annotation": "n_glycosylation_sequon" }, { "start_pos": 338, "end_pos": 340, "annotation": "n_glycosylation_sequon" }, { "start_pos": 69, "end_pos": 71, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "48940", "name": "", "equation": "an L-aminoacyl-L-amino acid + H2O = 2 an L-alpha-amino acid", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XR67-1", "F1NQJ0-1" ], "evidence": [ { "id": "48940", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/48940" } ] }, { "id": "R-GGA-266012", "name": "LTD4 is converted to LTE4 by DPEP1/2", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "extracellular region, plasma membrane", "input_participant_list": [ "R-ALL-266074" ], "output_participant_list": [ "R-ALL-266029", "R-ALL-266033" ], "enzyme_list": [ "F1NQJ0-1", "A0A8V0XR67-1" ], "evidence": [ { "id": "R-GGA-266012", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-266012" } ] }, { "id": "R-GGA-5433067", "name": "DPEPs hydrolyse glycine from AFXBO-CG, AFNBO-CG", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1NQJ0-1", "A0A8V0XR67-1" ], "evidence": [ { "id": "R-GGA-5433067", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5433067" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-266029", "participant_name": "Gly [extracellular region]", "crossref": [ { "id": "C00037", "database": "COMPOUND", "url": "" }, { "id": "57305", "database": "ChEBI", "url": "" }, { "id": "ZINC000004658552", "database": "ZINC", "url": "" } ] }, { "participant_id": "R-ALL-266033", "participant_name": "LTE4 [extracellular region]", "crossref": [ { "id": "C05952", "database": "COMPOUND", "url": "" }, { "id": "57462", "database": "ChEBI", "url": "" }, { "id": "ZINC000004629873", "database": "ZINC", "url": "" } ] }, { "participant_id": "R-ALL-266074", "participant_name": "LTD4 [extracellular region]", "crossref": [ { "id": "63166", "database": "ChEBI", "url": "" }, { "id": "52940265", "database": "PubChem Compound", "url": "" }, { "id": "CPD66-21", "database": "AraCyc", "url": "" }, { "id": "ZINC000004632133", "database": "ZINC", "url": "" }, { "id": "C05951", "database": "COMPOUND", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A0A8V0XR67", "gene_name": "DPEP1", "activity": [ { "ec_number": "3.4.13.19", "activity": "an L-aminoacyl-L-amino acid + H2O = 2 an L-alpha-amino acid.", "evidence": [ { "id": "A0A8V0XR67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XR67" } ] }, { "ec_number": "3.4.13.19", "activity": "", "evidence": [ { "id": "A0A8V0XR67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XR67" } ] } ] }, { "uniprot_ac": "F1NQJ0", "gene_name": "DPEP2", "activity": [ { "ec_number": "3.4.13.19", "activity": "an L-aminoacyl-L-amino acid + H2O = 2 an L-alpha-amino acid.", "evidence": [ { "id": "F1NQJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NQJ0" } ] }, { "ec_number": "3.4.13.19", "activity": "", "evidence": [ { "id": "F1NQJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NQJ0" } ] } ] } ], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1NQJ0-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 419, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1NQJ0-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1NQJ0" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "3.4.13.19", "ec_name": "an L-aminoacyl-L-amino acid + H2O = 2 an L-alpha-amino acid.", "evidence": [ { "id": "3.4.13.19", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:3.4.13.19" }, { "id": "3.4.13.19", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=3.4.13.19" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 191, "end_pos": 193 }, { "start_pos": 246, "end_pos": 248 }, { "start_pos": 283, "end_pos": 285 }, { "start_pos": 338, "end_pos": 340 }, { "start_pos": 69, "end_pos": 71 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1NQP5-1", "uniprot_ac": "F1NQP5", "uniprot_id": "F1NQP5_CHICK", "mass": { "chemical_mass": 84824.0, "monoisotopic_mass": 84824.0 }, "refseq": { "ac": "XP_424996", "name": "myotubularin-related protein 12", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_424996" }, "gene_names": [ { "name": "MTMR12", "type": "recommended", "evidence": [ { "id": "F1NQP5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NQP5" } ] }, { "name": "MTMR12", "type": "synonym", "evidence": [ { "id": "XP_424996", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_424996" } ] } ], "protein_names": [ { "name": "Myotubularin-related protein 12", "type": "recommended", "evidence": [ { "id": "F1NQP5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NQP5/entry#names_and_taxonomy" } ] }, { "name": "Inactive phosphatidylinositol 3-phosphatase 12", "type": "synonym", "evidence": [ { "id": "F1NQP5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NQP5/entry#names_and_taxonomy" } ] }, { "name": "myotubularin-related protein 12", "type": "synonym", "evidence": [ { "id": "XP_424996", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_424996" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052572.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Dec 16, 2011 this sequence version replaced XP_424996.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_424996", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_424996" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NQP5", "url": "https://www.uniprot.org/uniprotkb/F1NQP5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MTMR12", "url": "https://www.uniprot.org/uniprotkb/F1NQP5", "locus": { "chromosome": "Z", "start_pos": 10262139, "end_pos": 10295341, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010014887", "url": "https://www.ensembl.org/id/ENSGALG00010014887" } ] } } ], "crossref": [ { "id": "F1NQP5", "url": "https://alphafold.ebi.ac.uk/entry/F1NQP5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000003168", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000003168", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd13348", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13348", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd14594", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14594", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "427423", "url": "https://www.ncbi.nlm.nih.gov/gene/427423", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR010569", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010569", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR022587", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022587", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029021", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029021", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR030564", "url": "https://www.ebi.ac.uk/interpro/entry/IPR030564", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR030576", "url": "https://www.ebi.ac.uk/interpro/entry/IPR030576", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:427423", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427423", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DVLRFQG", "url": "https://omabrowser.org/oma/group/DVLRFQG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1NQP5", "url": "https://www.orthodb.org/?gene=F1NQP5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10807", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10807", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10807:SF37", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10807:SF37", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF06602", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06602", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12578", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12578", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-1660516", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1660516", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_424996", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_424996", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1NQP5", "url": "https://www.uniprot.org/uniprotkb/F1NQP5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NQP5-1", "url": "https://www.uniprot.org/uniprotkb/F1NQP5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLGSGAKAAKPSFVSYISPEEIHVKEPIEKEVNPHLLPGEQLLCEASTVYKYIQEDGSNRGTYGKLVCTNFKIAFLDDDSTSDDNEPQFKNKIIGENDITLQCVDQIYGVYDEKKKLLTGQLRKYPEKLIIYCKDLRVFNFCLRYTKEEEVKRIVSGIIHHSQTPKLLKRLFLFSYASAAPNNTDARNQTVMFDTLEDWRDELERTKGNVQYKAVSTNEGYRVSEKLPLYFVVPICVSEESILKYEGRGIPIWCWSCHNGAALLKMSAFPKEQDDSASQMQKAFLDGIYRTIRKPPYELLKTDDLSSSLPSLQEIQTAYTRFKQLFLIDNSTDFWATDVKWFSLLESTNWLEIIRRVLKKAIEVVECLERQHTNVLLIEENATDLCCVISSLVQVMMDSYSRTKLGFQSLIQKEWVIGGHGFLDRCNHLHKSDKEEAPVFLLLLNCVWQLVQQYPPAFEFTETYLTVLSDSLYVPIFSTFFFNSQHQKDTTATGESLKTQSGPFRFLTVWDWSVQFDLKAQAFLNNPLYAEKPKPEKSQRKTARFKHQRQLSLPLTQTKSSPKRGFFREETDHLIKNILGKRIGKFINSSDEPPNNFREFYDSWHSKPVDYHGLLLPRIDGPEIKVWAQRYLRWIPEAQLHGGGTIATAAKILDLMEEVQNLQVKMDEEHSQAVSGGIHAVPMLRNSARLSSLFPFALLQRQSVKPALPTSTWKDLEDEDDLVKRDDEFVDLSSDIL", "length": 737, "header": "tr|F1NQP5-1|F1NQP5_CHICK Isoform 1 of Myotubularin-related protein 12 OS=Gallus gallus OX=9031 GN=MTMR12 PE=1 SV=2 CANONICAL=F1NQP5-1" }, "isoforms": [ { "isoform_ac": "F1NQP5-1", "url": "https://www.uniprot.org/uniprotkb/F1NQP5/entry#F1NQP5-1", "sequence": { "sequence": "MLGSGAKAAKPSFVSYISPEEIHVKEPIEKEVNPHLLPGEQLLCEASTVYKYIQEDGSNRGTYGKLVCTNFKIAFLDDDSTSDDNEPQFKNKIIGENDITLQCVDQIYGVYDEKKKLLTGQLRKYPEKLIIYCKDLRVFNFCLRYTKEEEVKRIVSGIIHHSQTPKLLKRLFLFSYASAAPNNTDARNQTVMFDTLEDWRDELERTKGNVQYKAVSTNEGYRVSEKLPLYFVVPICVSEESILKYEGRGIPIWCWSCHNGAALLKMSAFPKEQDDSASQMQKAFLDGIYRTIRKPPYELLKTDDLSSSLPSLQEIQTAYTRFKQLFLIDNSTDFWATDVKWFSLLESTNWLEIIRRVLKKAIEVVECLERQHTNVLLIEENATDLCCVISSLVQVMMDSYSRTKLGFQSLIQKEWVIGGHGFLDRCNHLHKSDKEEAPVFLLLLNCVWQLVQQYPPAFEFTETYLTVLSDSLYVPIFSTFFFNSQHQKDTTATGESLKTQSGPFRFLTVWDWSVQFDLKAQAFLNNPLYAEKPKPEKSQRKTARFKHQRQLSLPLTQTKSSPKRGFFREETDHLIKNILGKRIGKFINSSDEPPNNFREFYDSWHSKPVDYHGLLLPRIDGPEIKVWAQRYLRWIPEAQLHGGGTIATAAKILDLMEEVQNLQVKMDEEHSQAVSGGIHAVPMLRNSARLSSLFPFALLQRQSVKPALPTSTWKDLEDEDDLVKRDDEFVDLSSDIL", "length": 737, "header": "tr|F1NQP5-1|F1NQP5_CHICK Isoform 1 of Myotubularin-related protein 12 OS=Gallus gallus OX=9031 GN=MTMR12 PE=1 SV=2 CANONICAL=F1NQP5-1" }, "locus": { "chromosome": "Z", "start_pos": 10295226, "end_pos": 10264622, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010035814.1", "url": "https://www.ensembl.org/id/ENSGALT00010035814.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020769.1", "url": "https://www.ensembl.org/id/ENSGALP00010020769.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:427423", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427423", "resource": "KEGG Pathway" }, { "id": "R-GGA-1660516", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1660516", "resource": "Reactome", "description": "Synthesis of PIPs at the early endosome membrane" } ], "orthologs": [ { "uniprot_canonical_ac": "A2BGG1-1", "protein_name": "Myotubularin-related protein 12", "gene_name": "mtmr12", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLSLGSGGAKSSKPSFVSYVTPEEIKLEKDPQKKEKHPDLLPGEVVFCSANPILKYTQDDLSQRGVFGTLLCTNFRVAFISDDAPQEEMSKTFKNKLYGENDIPLMCVDHIYGVYDEKRKLITGGLVKNKCPSKMIIHCKDLRVFQFCLTFSKEEDAKRIFQGIAHHCLEEKSLKCVFAFSYLRSTNPEMLRKREAIMFDSPEDWTQEMKRTKAQCRLVTENENFELSQRLPQYFVIPSALGDLFNYQGKGLPIWCWSHHSGCALFKASFPSMTQEDGDFQSHLDTMITAVARNYLYSVKTEDLSESLPTLQDIQQSYNKFKQYFLIDNTTDFWLSDVKWFSSLESSGWLDIIRQCLQKAVEVVECLEKDNTNVLITEEEGTDLCCVISSLAQIMLDPYYRTLMGFQSLVQKEWVAGCHAFLDRCNHLHQKDKECHSPVFLLFLECVWQLVQQHSPAFQFSETYLTVLSDSVHVPIFSTFLFNSAHHRESVMKAESPIAQSRPLSCPTVWDWSVQFDSKAQNFFFNPLYSEKVKHERTVRRPHKHKHQRQLSLPSSAFKTPTKKGFFKDETDSLKKMLRVKRISRWMGSPDSPVVASREFYESWQQRPLDYHGLLLPSLDGPSVRIWMQRYLRWIPEVHIMGGGSVAIMTKLMELLSQVEDLKRVLEQRDPSLATQPDHPPPLHHRLPSFGSSGRLSSSFPFTYSRNRSFKPIIPTGLMQSLMVADNLANQEDETS", "length": 736 }, "evidence": [ { "id": "F1NQP5", "url": "https://omabrowser.org/oma/group/F1NQP5/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q5FVM6-1", "protein_name": "Myotubularin-related protein 12", "gene_name": "Mtmr12", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLGKGGVGGGGGTKAPKPSFVSYVRPEEIHTNEKEVTEKEEVTLHLLPGEQLLCEASTVLKYVQEDSCQLGICGRLVCTDFRISFLGDEGSAVDNGAETHFKNKIIGVNDIPLHCVDQIYGVFDEKKKPLFGQLKKYPEKLVIHCKDLRVLHFCLRYTKEEEVKRIVSGIIHHTQSPKLLKRLFLFSYAAAVHGTAADPRNCTVMFDTPKDWCWELERTKGSVKYKTVSVNEGYRVCDRLPAYFVVPTPLLEDDVKRFQGRGIPIWCWSCHNGSALLKMSALPKEQDDSALQIQKSFLDGIYKTIHRPPYEMVKTEDLSSNFLSLQEIQSSYCKFKQLFLIDSSSEFWDTDVKWFSLLESSGWLDIIRRCLKRAIEIIECLEAQNMNVLLLEENASDLCCLLSSLVQVMMDAHCRTWTGFQSLIQKEWVMGGHSFLDRCNHLHQSDKEEVPVFLLFLDCVWQLVHQHPPAFEFTETYLTVLSDSLYIPIFSTFFFNSPHQKDTNMGRESLDAQSKPLTLLTVWDWSVQFEPKAQTLLRNPLYVEKPKLDKGQRKGSRFKHQRQLSLPLTQSKSSPKRGFFREETDHLIKNLLGKRISKLINSSDDLQDNSREFYDNWHSKPTDYHGLLLPHIEGPEIKVWAQRYLRWIPEAQILGGGRVATMGKLLEMMEEVQSLQEKIEARHHRQEAIHVQAPGLLRNSARLSSLFPFAMHQRHSAKPVLPTSGWKALGGEDDLAKREDEFVDLGDV", "length": 748 }, "evidence": [ { "id": "F1NQP5", "url": "https://omabrowser.org/oma/group/F1NQP5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q80TA6-1", "protein_name": "Myotubularin-related protein 12", "gene_name": "Mtmr12", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLGKGGVGGGGGTKAPKPSFVSYVRPEEIHTDEKEVTEKEVTLHLLPGEQLLCEASTVLKYVQEDSCQRGVYGRLVCTDFKISFLGDEDSALDNGGEAQFKNKIIGVNDVPLHCVDQIYGVFDEKKKPLFGQLKKYPEKLVIHCKDLRVLHFCLRYTKEEEVKRIVSGIIHHTQSPKLLKRLFLFSYAAAVHGTATDSRNCTVMFDTPKDWCWELERTKGSVKYRTVSVNEGYRVSDRLPAYFVVPTPLPEDDVRRFQGHGIPIWCWSCHNGSALLKMSALPKEQDDGALQVQKSFLDGIYKTIHRPPYEMVKTEDLSSNFLSLQEIQSAYCKFKQLFLIDNSSEFWDTDIKWFSLLESSSWLDIIRRCLKKAIEITECLEAQNVNVLLLEENASDLCCLLSSLVQVMMDAHCRTRTGFQSLIQKEWVMGGHSFLDRCNHLHQSDKEEVPIFLLFLDCVWQLVHQYPPAFEFTETYLTVLSDSLYIPIFSTFFFNSPHQKDTNMGRENLDAQSKPLTLLTVWDWSVQFEPKAQTLLRNPLYVEKPKLDRGQQKGSRFKHQRQLSLPLTQSKSSPKRGFFREETDHLIKNLLGKRISKLINSSDDLQDSSREFYDSWHSKPTDYHGLLLPHIEGPEIKVWAQRYLRWIPEAQILGGGRVATMGKLLEMMEEVQSLQEKIEARHHRQEAVHAEAPGLLRNSVRLSSLFPFALLQRHSAKPVLPTSGWKALGGEDDLAKREDEFVDLGDV", "length": 747 }, "evidence": [ { "id": "F1NQP5", "url": "https://omabrowser.org/oma/group/F1NQP5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9C0I1-1", "protein_name": "Myotubularin-related protein 12", "gene_name": "MTMR12", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLGKGVVGGGGGTKAPKPSFVSYVRPEEIHTNEKEVTEKEVTLHLLPGEQLLCEASTVLKYVQEDSCQHGVYGRLVCTDFKIAFLGDDESALDNDETQFKNKVIGENDITLHCVDQIYGVFDEKKKTLFGQLKKYPEKLIIHCKDLRVFQFCLRYTKEEEVKRIVSGIIHHTQAPKLLKRLFLFSYATAAQNNTVTDPKNHTVMFDTLKDWCWELERTKGNMKYKAVSVNEGYKVCERLPAYFVVPTPLPEENVQRFQGHGIPIWCWSCHNGSALLKMSALPKEQDDGILQIQKSFLDGIYKTIHRPPYEIVKTEDLSSNFLSLQEIQTAYSKFKQLFLIDNSTEFWDTDIKWFSLLESSSWLDIIRRCLKKAIEITECMEAQNMNVLLLEENASDLCCLISSLVQLMMDPHCRTRIGFQSLIQKEWVMGGHCFLDRCNHLRQNDKEEVPVFLLFLDCVWQLVHQHPPAFEFTETYLTVLSDSLYIPIFSTFFFNSPHQKDTNMGREGQDTQSKPLNLLTVWDWSVQFEPKAQTLLKNPLYVEKPKLDKGQRKGMRFKHQRQLSLPLTQSKSSPKRGFFREETDHLIKNLLGKRISKLINSSDELQDNFREFYDSWHSKSTDYHGLLLPHIEGPEIKVWAQRYLRWIPEAQILGGGQVATLSKLLEMMEEVQSLQEKIDERHHSQQAPQAEAPCLLRNSARLSSLFPFALLQRHSSKPVLPTSGWKALGDEDDLAKREDEFVDLGDV", "length": 747 }, "evidence": [ { "id": "F1NQP5", "url": "https://omabrowser.org/oma/group/F1NQP5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1NQP5", "url": "https://www.uniprot.org/uniprotkb/F1NQP5" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "F1NQP5", "url": "https://www.uniprot.org/uniprotkb/F1NQP5" } ], "pmid": "" }, { "name": "sarcomere", "id": "GO:0030017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030017", "evidence": [ { "database": "UniProtKB", "id": "F1NQP5", "url": "https://www.uniprot.org/uniprotkb/F1NQP5" } ], "pmid": "" }, { "name": "sarcoplasmic reticulum", "id": "GO:0016529", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016529", "evidence": [ { "database": "UniProtKB", "id": "F1NQP5", "url": "https://www.uniprot.org/uniprotkb/F1NQP5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 182, "end_pos": 184, "annotation": "n_glycosylation_sequon" }, { "start_pos": 188, "end_pos": 190, "annotation": "n_glycosylation_sequon" }, { "start_pos": 330, "end_pos": 332, "annotation": "n_glycosylation_sequon" }, { "start_pos": 381, "end_pos": 383, "annotation": "n_glycosylation_sequon" }, { "start_pos": 588, "end_pos": 590, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1NQP5-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 737, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1NQP5-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1NQP5" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1NQP5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NQP5" }, { "id": "PS51339", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51339" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Myotubularin phosphatase", "eco_id": "ECO_0000259", "start_pos": 193, "end_pos": 631, "start_aa": "Phe", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 182, "end_pos": 184 }, { "start_pos": 188, "end_pos": 190 }, { "start_pos": 330, "end_pos": 332 }, { "start_pos": 381, "end_pos": 383 }, { "start_pos": 588, "end_pos": 590 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": 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{ "uniprot_canonical_ac": "F1NQU7-1", "uniprot_ac": "F1NQU7", "uniprot_id": "F1NQU7_CHICK", "mass": { "chemical_mass": 97530.0, "monoisotopic_mass": 97530.0 }, "refseq": {}, "gene_names": [ { "name": "EIF4G2", "type": "recommended", "evidence": [ { "id": "F1NQU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NQU7" } ] } ], "protein_names": [ { "name": "Eukaryotic translation initiation factor 4 gamma 2", "type": "recommended", "evidence": [ { "id": "F1NQU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NQU7/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Appears to play a role in the switch from cap-dependent to IRES-mediated translation during mitosis, apoptosis and viral infection. 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"url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZH29", "url": "https://www.orthodb.org/?gene=A0A8V0ZH29", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NQU7", "url": "https://www.orthodb.org/?gene=F1NQU7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23253", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23253", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23253:SF9", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23253:SF9", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02020", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02020", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02847", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02847", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02854", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02854", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0ZH29", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH29", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZH29-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH29-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NQU7", "url": "https://www.uniprot.org/uniprotkb/F1NQU7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NQU7-1", "url": "https://www.uniprot.org/uniprotkb/F1NQU7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": 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gallus OX=9031 GN=EIF4G2 PE=1 SV=1 CANONICAL=F1NQU7-1" }, "locus": { "chromosome": "5", "start_pos": 8434883, "end_pos": 8427175, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050911.1", "url": "https://www.ensembl.org/id/ENSGALT00010050911.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030102.1", "url": "https://www.ensembl.org/id/ENSGALP00010030102.1" } ] } }, { "isoform_ac": "F1NQU7-1", "url": "https://www.uniprot.org/uniprotkb/F1NQU7/entry#F1NQU7-1", "sequence": { "sequence": "VESAIAEGGASRFSASSGGGGGRGAPQHYPKTASNSEFLGKTPGQNAQKWIPSRSTRRDDDSANDKERHDAIFRKVRGILNKLTPEKFDKLCLELLNVGVESKLILKGVILLIVDKALEEPKYSSLYAQLCLRLAEDAPNFDGPSAESHPGQKQSTTFRRLLISKLQDEFENRTRNVDIYDKHDGPLLPEEEEQRAIAKIKMLGNIKFIGELGKLDLIHESILHKCIKTLLEKKKRVQLKDMGEDLECLCQIMRTVGPRLDHAKAKSLMDQYFARMRSLMSSKELPARIRFLLQDTVELREHNWVPRKAFLDNGPKTINQIRQDAVKDLGVFIPAPMSQVMRSDFFLEGPFMPPRMKLDRDPLGGLADMFGQMPGSGIGTGPGVIQDRFSPTMGRHRSNQLFNGHGGHLMPSAQPQFGELGKSFLKNQISLRPAQAFLMNKNQVPKLQPQITMIPPSAQPPRTQTPPLGQPPQLGLKTNPPLIQEKPAKTTKKPPPSKEELLKQTEAVVTEYLNNGNANDAVNAVREMRAPKHFIPEMLSKVISQSLDRSDEDKEKASTLISLLKQEGIATSDNFMQAFLNVLDQCPKLEVDIPLVKSYLAQFAARAIISELVSISELAQPLESGTHFPLFLLCLQQLAKLQDREWLTELFQQSKVNMQKMLPEIDQNKDRMLEILEGKGLSFLFPLLKLEKELLKQIKSDPSPQAIYKWIKDNISPKLHVDKGFVNILMTSFLQYISSEVNPPSDESDSSSAPSKEQLEQEKQLLLSFKPVMQKFLHDHVDLQVSALYALQVHCYNSNFPKGMLLRFFVHFYDMEIIEEEAFLAWKEDITQEFPGKGKALFQVNQWLTWLETAEEEESEEEAD", "length": 864, "header": "tr|F1NQU7-1|F1NQU7_CHICK Isoform 1 of Eukaryotic translation initiation factor 4 gamma 2 OS=Gallus gallus OX=9031 GN=EIF4G2 PE=1 SV=1 CANONICAL=F1NQU7-1" }, "locus": { "chromosome": "5", "start_pos": 8434883, "end_pos": 8426420, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050914.1", "url": "https://www.ensembl.org/id/ENSGALT00010050914.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030105.1", "url": "https://www.ensembl.org/id/ENSGALP00010030105.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "F1NQU7", "url": "https://www.uniprot.org/uniprotkb/F1NQU7" } ], "pmid": "" }, { "name": "translation factor activity, RNA binding", "id": "GO:0008135", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008135", "evidence": [ { "database": "UniProtKB", "id": "F1NQU7", "url": "https://www.uniprot.org/uniprotkb/F1NQU7" } ], "pmid": "" }, { "name": "translation initiation factor activity", "id": "GO:0003743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003743", "evidence": [ { "database": "UniProtKB", "id": "F1NQU7", "url": "https://www.uniprot.org/uniprotkb/F1NQU7" } ], "pmid": "" }, { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "F1NQU7", "url": "https://www.uniprot.org/uniprotkb/F1NQU7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F1NQU7", "url": "https://www.uniprot.org/uniprotkb/F1NQU7" } ], "pmid": "" }, { "name": "eukaryotic translation initiation factor 4F complex", "id": "GO:0016281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016281", "evidence": [ { "database": "UniProtKB", "id": "F1NQU7", "url": "https://www.uniprot.org/uniprotkb/F1NQU7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "positive regulation of cell growth", "id": "GO:0030307", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030307", "evidence": [ { "database": "UniProtKB", "id": "F1NQU7", "url": "https://www.uniprot.org/uniprotkb/F1NQU7" } ], "pmid": "" }, { "name": "translational initiation", "id": "GO:0006413", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006413", "evidence": [ { "database": "UniProtKB", "id": "F1NQU7", "url": "https://www.uniprot.org/uniprotkb/F1NQU7" } ], "pmid": "" }, { "name": "negative regulation of autophagy", "id": "GO:0010507", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010507", "evidence": [ { "database": "UniProtKB", "id": "F1NQU7", "url": "https://www.uniprot.org/uniprotkb/F1NQU7" } ], "pmid": "" }, { "name": "regulation of translational initiation", "id": "GO:0006446", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006446", "evidence": [ { "database": "UniProtKB", "id": "F1NQU7", "url": "https://www.uniprot.org/uniprotkb/F1NQU7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 172, "end_pos": 174, "annotation": "n_glycosylation_sequon" }, { "start_pos": 714, "end_pos": 716, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1NQU7-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 864, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1NQU7-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1NQU7" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 172, "end_pos": 174 }, { "start_pos": 714, "end_pos": 716 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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{ "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1NRC6-1", "uniprot_ac": "F1NRC6", "uniprot_id": "F1NRC6_CHICK", "mass": { "chemical_mass": 65732.0, "monoisotopic_mass": 65732.0 }, "refseq": { "ac": "NP_990159", "name": "E3 ubiquitin-protein ligase RLIM isoform 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990159" }, "gene_names": [ { "name": "RLIM", "type": "recommended", "evidence": [ { "id": "F1NRC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NRC6" } ] }, { "name": "R-LIM", "type": "synonym", "evidence": [ { "id": "NP_990159", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990159" } ] }, { "name": "RLIM", "type": "synonym", "evidence": [ { "id": "NP_990159", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990159" } ] }, { "name": "RNF12", "type": "synonym", "evidence": [ { "id": "NP_990159", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990159" } ] } ], "protein_names": [ { "name": "RING-type E3 ubiquitin transferase", "type": "recommended", "evidence": [ { "id": "F1NRC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NRC6/entry#names_and_taxonomy" } ] }, { "name": "2.3.2.27", "type": "synonym", "evidence": [ { "id": "F1NRC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NRC6/entry#names_and_taxonomy" } ] }, { "name": "E3 ubiquitin-protein ligase RLIM isoform 1", "type": "synonym", "evidence": [ { "id": "NP_990159", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990159" } ] }, { "name": "E3 ubiquitin-protein ligase RLIM", "type": "synonym", "evidence": [ { "id": "NP_990159", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990159" } ] }, { "name": "LIM domain interacting RING finger protein", "type": "synonym", "evidence": [ { "id": "NP_990159", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990159" } ] }, { "name": "ring finger protein 12", "type": "synonym", "evidence": [ { "id": "NP_990159", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990159" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AF069993.1, HAEK01045896.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN03579564, SAMN06140855 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000071.1. On Nov 17, 2021 this sequence version replaced NP_990159.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_990159", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990159" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NRC6", "url": "https://www.uniprot.org/uniprotkb/F1NRC6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RLIM", "url": "https://www.uniprot.org/uniprotkb/F1NRC6", "locus": { "chromosome": "4", "start_pos": 12297180, "end_pos": 12315516, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013408", "url": "https://www.ensembl.org/id/ENSGALG00010013408" } ] } } ], "crossref": [ { "id": "F1NRC6", "url": "https://alphafold.ebi.ac.uk/entry/F1NRC6", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000007750", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000007750", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd16674", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16674", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "395630", "url": "https://www.ncbi.nlm.nih.gov/gene/395630", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001841", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001841", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051834", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051834", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR058896", "url": "https://www.ebi.ac.uk/interpro/entry/IPR058896", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:395630", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:395630", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YEGGHEG", "url": "https://omabrowser.org/oma/group/YEGGHEG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YJT3", "url": "https://www.orthodb.org/?gene=A0A8V0YJT3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YSA3", "url": "https://www.orthodb.org/?gene=A0A8V0YSA3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NRC6", "url": "https://www.orthodb.org/?gene=F1NRC6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45931", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45931", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45931:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45931:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13639", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13639", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25914", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25914", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-983168", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983168", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_990159", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990159", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YJT3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJT3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJT3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJT3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YSA3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSA3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YSA3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSA3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NRC6", "url": "https://www.uniprot.org/uniprotkb/F1NRC6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NRC6-1", "url": "https://www.uniprot.org/uniprotkb/F1NRC6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MESSDSSDKGNIDQSEAQRQSQLDRLDREEAFYQFVNNLSEEDYRLMRDNNLLGTPGEITEEELLRRLHQVKEGPPQQNSDENRGAESTEDVSNGDSIIDWLNSVRQTGNTTRSGQRGNQSWRAVSRTNPNSGDFRFSLEINVNRNNGNTNPETENEPSAEPSGGEDLENSQSDSEIPRSESPSVRQPGSERSTSEELTEEASPRGQRRARSRSPEQRRTRARTDRSRSPINPVSEAPRRSHHNTSSQTFDHSAVNEAEGSSRTRQHVTLRQHAVGTEIPSENAVLFSAPETRPVPQAAGSSETNGASESAAPGQRPPTIVLDLQVRRVRPGEYRQRDSIANRTRSRSQTPNNTVTYESERGGFRRTFSRSERAGVRTYVSTIRIPIRRILNTGLSETTSVAIQTMLRQIMTGFGELSYFMYSDSDADPSGPTPNQNVDASEPQNGGSGSSSNESTDVSSGEVFEGSNEGGSTSGARREGRNTRGSVTFEESGSLPFLSLAQFFLLNEDDDDQPRGLTKEQIDNLAMRNFGESDALKTCSVCITEYTEGNKLRKLPCSHEYHVHCIDRWLSENSTCPICRRAVLASGNRESVV", "length": 593, "header": "tr|F1NRC6-1|F1NRC6_CHICK Isoform 1 of RING-type E3 ubiquitin transferase OS=Gallus gallus OX=9031 GN=RLIM PE=3 SV=1 CANONICAL=F1NRC6-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YJT3-1", "url": "https://www.uniprot.org/uniprotkb/F1NRC6/entry#A0A8V0YJT3-1", "sequence": { "sequence": "MESSDSSDKGNIDQSEAQRQSQLDRLDREEAFYQFVNNLSEEDYRLMRDNNLLGTPGEITEEELLRRLHQVKEGPPQQNSDENRGAESTEDVSNGDSIIDWLNSVRQTGNTTRSGQRGNQSWRAVSRTNPNSGDFRFSLEINVNRNNGNTNPETENEPSAEPSGGEDLENSQSDSEIPRSESPSVRQPGSERSTSEELTEEASPRGQRRARSRSPEQRRTRARTDRSRSPINPVSEAPRRSHHNTSSQTFDHSAVNEAEGSSRTRQHVTLRQHAVGTEIPSENAVLFSAPETRPVPQAAGSSETNGASESAAPGQRPPTIVLDLQVRRVRPGEYRQRDSIANRTRSRSQTPNNTVTYESERGGFRRTFSRSERAGVRTYVSTIRIPIRRILNTGLSETTSVAIQTMLRQIMTGFGELSYFMYSDSDADPSGPTPNQNVDASEPQNGGSGSSSNESTDVSSGEVFEGSNEGGSTSGARREGRNTRGSVTFEESGSLPFLSLAQFFLLNEDDDDQPRGLTKEQIDNLAMRNFGGMQQLASQLQPYEGLKWPFWWLSNA", "length": 556, "header": "tr|A0A8V0YJT3-1|A0A8V0YJT3_CHICK Computationally mapped isoform of RING-type E3 ubiquitin transferase OS=Gallus gallus OX=9031 GN=RLIM PE=4 SV=1 CANONICAL=F1NRC6-1" }, "locus": { "chromosome": "4", "start_pos": 12305943, "end_pos": 12299064, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032282.1", "url": "https://www.ensembl.org/id/ENSGALT00010032282.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019072.1", "url": "https://www.ensembl.org/id/ENSGALP00010019072.1" } ] } }, { "isoform_ac": "A0A8V0YSA3-1", "url": "https://www.uniprot.org/uniprotkb/F1NRC6/entry#A0A8V0YSA3-1", "sequence": { "sequence": "AIIFLEKLTPKLAQYSNFGSSLSVFTGAESTEDVSNGDSIIDWLNSVRQTGNTTRSGQRGNQSWRAVSRTNPNSGDFRFSLEINVNRNNGNTNPETENEPSAEPSGGEDLENSQSDSEIPRSESPSVRQPGSERSTSEELTEEASPRGQRRARSRSPEQRRTRARTDRSRSPINPVSEAPRRSHHNTSSQTFDHSAVNEAEGSSRTRQHVTLRQHAVGTEIPSENAVLFSAPETRPVPQAAGSSETNGASESAAPGQRPPTIVLDLQVRRVRPGEYRQRDSIANRTRSRSQTPNNTVTYESERGGFRRTFSRSERAGVRTYVSTIRIPIRRILNTGLSETTSVAIQTMLRQIMTGFGELSYFMYSDSDADPSGPTPNQNVDASEPQNGGSGSSSNESTDVSSGEVFEGSNEGGSTSGARREGRNTRGSVTFEESGSLPFLSLAQFFLLNEDDDDQPRGLTKEQIDNLAMRNFGESDALKTCSVCITEYTEGNKLRKLPCSHEYHVHCIDRWLSENSTCPICRRAVLASGNRESVV", "length": 535, "header": "tr|A0A8V0YSA3-1|A0A8V0YSA3_CHICK Computationally mapped isoform of RING-type E3 ubiquitin transferase OS=Gallus gallus OX=9031 GN=RLIM PE=3 SV=1 CANONICAL=F1NRC6-1" }, "locus": { "chromosome": "4", "start_pos": 12304093, "end_pos": 12302489, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032284.1", "url": "https://www.ensembl.org/id/ENSGALT00010032284.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019074.1", "url": "https://www.ensembl.org/id/ENSGALP00010019074.1" } ] } }, { "isoform_ac": "F1NRC6-1", "url": "https://www.uniprot.org/uniprotkb/F1NRC6/entry#F1NRC6-1", "sequence": { "sequence": "MESSDSSDKGNIDQSEAQRQSQLDRLDREEAFYQFVNNLSEEDYRLMRDNNLLGTPGEITEEELLRRLHQVKEGPPQQNSDENRGAESTEDVSNGDSIIDWLNSVRQTGNTTRSGQRGNQSWRAVSRTNPNSGDFRFSLEINVNRNNGNTNPETENEPSAEPSGGEDLENSQSDSEIPRSESPSVRQPGSERSTSEELTEEASPRGQRRARSRSPEQRRTRARTDRSRSPINPVSEAPRRSHHNTSSQTFDHSAVNEAEGSSRTRQHVTLRQHAVGTEIPSENAVLFSAPETRPVPQAAGSSETNGASESAAPGQRPPTIVLDLQVRRVRPGEYRQRDSIANRTRSRSQTPNNTVTYESERGGFRRTFSRSERAGVRTYVSTIRIPIRRILNTGLSETTSVAIQTMLRQIMTGFGELSYFMYSDSDADPSGPTPNQNVDASEPQNGGSGSSSNESTDVSSGEVFEGSNEGGSTSGARREGRNTRGSVTFEESGSLPFLSLAQFFLLNEDDDDQPRGLTKEQIDNLAMRNFGESDALKTCSVCITEYTEGNKLRKLPCSHEYHVHCIDRWLSENSTCPICRRAVLASGNRESVV", "length": 593, "header": "tr|F1NRC6-1|F1NRC6_CHICK Isoform 1 of RING-type E3 ubiquitin transferase OS=Gallus gallus OX=9031 GN=RLIM PE=3 SV=1 CANONICAL=F1NRC6-1" }, "locus": { "chromosome": "4", "start_pos": 12305943, "end_pos": 12302489, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032279.1", "url": "https://www.ensembl.org/id/ENSGALT00010032279.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019069.1", "url": "https://www.ensembl.org/id/ENSGALP00010019069.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 433, "start_aa": "Thr", "end_pos": 433, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr433", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:395630", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:395630", "resource": "KEGG Pathway" }, { "id": "R-GGA-983168", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983168", "resource": "Reactome", "description": "Antigen processing: Ubiquitination & Proteasome degradation" } ], "orthologs": [ { "uniprot_canonical_ac": "E7FH41-1", "protein_name": "RING-type E3 ubiquitin transferase", "gene_name": "rlim", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEGQDNADQGSSDQSEIQRRRQLDRLDREEAFYQFVNNLSEEDYRLMRDNNLLGTPGEITADELLNRLRQVKDGPESPSSNITEERREAPGATEVEGTEENPSGETLLDWLNTVRQTGNTTRSGYRGNQSWRAVSQTNPNSGDFRFSLEINVNRNIAEQQTQTERLEGSQERPDGSVSEPESLMETAEVVEEPVVDELAVIVEPELPVPSTLTLNRDDNVPVDAPNPLTSTPPNLPSVEQPRRGQIRARSRSPEQRRTRARTARGRSPINLERLDGLPPTQHGIPTHNPEILPEPQVEGSSRTRQLFLSRQSTVETETHTLGSATDVPEAPQEREATTGEAGASGRRPPTIMLDLQVRRVRPGEYRQRDSIANRTRSRSQTSNNTLLYETERGGFRRTFSRSERAGVRTYVSTIRIPIRRISDAGLGEATSLALQSMIRQIMTGFGELSYFMEAEVPDSNREDNPPADLSDALGNPDASTGTGASEADPYLPGHGGLNQGGLEARTEEREVEGGLPGAAGPRENRGRQRAPINLDETGSLPFLRLAHFFLLNEEDDDQPRGLTKEQIDNLSMRNFGESDAFKTCSVCITEYAEGNKLRKLPCSHEYHVHCIDRWLSENSTCPICRRAVLISTNRESVV", "length": 638 }, "evidence": [ { "id": "F1NRC6", "url": "https://omabrowser.org/oma/group/F1NRC6/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1RPK6-1", "protein_name": "RING-type E3 ubiquitin transferase", "gene_name": "RLIM", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MESSDSNDKGSGDQSAAQRRSQMDRLDREEAFYQFVNNLSEEDYRLMRDNNLLGTPGESTEEELLRRLQQIKEGPPPQNSDENRGGDSSDDVSNGDSIIDWLNSVRQTGNTTRSGQRGNQSWRAVSRTNPNSGDFRFSLEINVNRNNGSQNPENENEPSARRSSGESMDNNSQRQVENPRSESASTRPPRSERNSTEALTGEVPPTRGQRRARSRSPDHRRTRARAERSRSPLHPMSEIPRRSHHSISSQTFEHPLVNETEGSSRTRHHVTLRQQISGPDLLSRGLFAASGTRNASPGAGSSDTTGNGESAGSGQRPPTIVLDLQVRRVRPGEYRQRDSIASRTRSRSQTPNNTVTYESERGGFRRTFSRSERAGVRTYVSTIRIPIRRILNTGLSETTSVAIQTMLRQIMTGFGELSYFMYSDSDSEPSGSVSSRNMERAESRNGRVGSGGSSSSGSSSSSSSSSSSSSSSSSSPSSSSSGESSETSSEVFEGSNEGSSSSGSSGARREGRHRAPVTFDESGSLPFLSLAQFFLLNEDDDDQPRGLTKEQIDNLAMRSFGENDALKTCSVCITEYTEGNKLRKLPCSHEYHVHCIDRWLSENSTCPICRRAVLASGNRESIV", "length": 623 }, "evidence": [ { "id": "F1NRC6", "url": "https://omabrowser.org/oma/group/F1NRC6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q4V889-1", "protein_name": "RING-type E3 ubiquitin transferase", "gene_name": "Rlim", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MENSDSNDKGSDQSAAQRRSQMDRLDREEAFYQFVNNLSEEDYRLMRDNNLLGTPGESTEEELLRRLQQIKEGPPPQSSDENRAGESSDDVSNSDSIIDWLNSVRQSGNTTRSGQRGNQSWRAVSRTNPNSGDFRFSLEINVNRNNGSQTSENENEPSTRRLSVESMESSSQRQMESHASESTSARPSRAERNSTEALEVPLTRGQRRARSRSPEHRRTRARAERSRSPLHPTIEIPRRAHHNISPQTLEQPLENEPEGSSRTRHHVTLRQQISGPELLGRGLFAASGSRNPSQGTSSSDTGSNSESSGSGQRPPTIVLDLQVRRVRPGEYRQRDSIASRTRSRSQTPNNTVTYESERGGFRRTFSRSERAGVRTYVSTIRIPIRRILNTGLSETTSVAIQTMLRQIMTGFGELSYFMYSDSDSEPSASVSSRNTERAESRNGRGSSGAGNSSASSSSPSPSSNGESSESSSDLFEGTSEGGPSGPSRRDGRHRAPVAFDESGSLPFLSLAQFFLLNEDDEDQPRGLTKEQIDNLAMRSFGENDALKTCSVCITEYTEGNKLRKLPCSHEYHVHCIDRWLSENSTCPICRRAVLSSGNRESVV", "length": 603 }, "evidence": [ { "id": "F1NRC6", "url": "https://omabrowser.org/oma/group/F1NRC6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9NVW2-1", "protein_name": "E3 ubiquitin-protein ligase RLIM", "gene_name": "RLIM", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MENSDSNDKGSGDQSAAQRRSQMDRLDREEAFYQFVNNLSEEDYRLMRDNNLLGTPGESTEEELLRRLQQIKEGPPPQNSDENRGGDSSDDVSNGDSIIDWLNSVRQTGNTTRSGQRGNQSWRAVSRTNPNSGDFRFSLEINVNRNNGSQNSENENEPSARRSSGENVENNSQRQVENPRSESTSARPSRSERNSTEALTEVPPTRGQRRARSRSPDHRRTRARAERSRSPLHPMSEIPRRSHHSISSQTFEHPLVNETEGSSRTRHHVTLRQQISGPELLSRGLFAASGTRNASQGAGSSDTAASGESTGSGQRPPTIVLDLQVRRVRPGEYRQRDSIASRTRSRSQTPNNTVTYESERGGFRRTFSRSERAGVRTYVSTIRIPIRRILNTGLSETTSVAIQTMLRQIMTGFGELSYFMYSDSDSEPTGSVSNRNMERAESRSGRGGSGGGSSSGSSSSSSSSSSSSSSSSSSSSPSSSSGGESSETSSDLFEGSNEGSSSSGSSGARREGRHRAPVTFDESGSLPFLSLAQFFLLNEDDDDQPRGLTKEQIDNLAMRSFGENDALKTCSVCITEYTEGNKLRKLPCSHEYHVHCIDRWLSENSTCPICRRAVLASGNRESVV", "length": 624 }, "evidence": [ { "id": "F1NRC6", "url": "https://omabrowser.org/oma/group/F1NRC6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9WTV7-1", "protein_name": "E3 ubiquitin-protein ligase RLIM", "gene_name": "Rlim", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MENSDSNDKGSDQSAAQRRSQMDRLDREEAFYQFVNNLSEEDYRLMRDNNLLGTPGESTEEELLRRLQQIKEGPPPQSPDENRAGESSDDVTNSDSIIDWLNSVRQTGNTTRSGQRGNQSWRAVSRTNPNSGDFRFSLEINVNRNNGSQTSENESEPSTRRLSVENMESSSQRQMENSASESASARPSRAERNSAEAVTEVPTTRAQRRARSRSPEHRRTRARAERSRSPLQPTSEIPRRAPTLEQSSENEPEGSSRTRHHVTLRQQISGPELLGRGLFAASGSRNPSQGTSSSDTGSNSESSGSGQRPPTIVLDLQVRRVRPGEYRQRDSIASRTRSRSQAPNNTVTYESERGGFRRTFSRSERAGVRTYVSTIRIPIRRILNTGLSETTSVAIQTMLRQIMTGFGELSYFMYSDSDSEPSASVSSRNVERVESRNGRGSSGGGNSSGSSSSSSPSPSSSGESSESSSEMFEGSSEGGSSGPSRRDGRHRAPVTFDESGSLPFLSLAQFFLLNEDDEDQPRGLTKEQIDNLAMRSFGENDALKTCSVCITEYTEGNKLRKLPCSHEYHVHCIDRWLSENSTCPICRRAVLSSGNRESVV", "length": 600 }, "evidence": [ { "id": "F1NRC6", "url": "https://omabrowser.org/oma/group/F1NRC6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "random inactivation of X chromosome", "id": "GO:0060816", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060816", "evidence": [ { "database": "UniProtKB", "id": "F1NRC6", "url": "https://www.uniprot.org/uniprotkb/F1NRC6" } ], "pmid": "" }, { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "F1NRC6", "url": "https://www.uniprot.org/uniprotkb/F1NRC6" } ], "pmid": "" }, { "name": "ubiquitin-dependent protein catabolic process", "id": "GO:0006511", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006511", "evidence": [ { "database": "UniProtKB", "id": "F1NRC6", "url": "https://www.uniprot.org/uniprotkb/F1NRC6" } ], "pmid": "" }, { "name": "regulation of neurogenesis", "id": "GO:0050767", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050767", "evidence": [ { "database": "UniProtKB", "id": "F1NRC6", "url": "https://www.uniprot.org/uniprotkb/F1NRC6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1NRC6", "url": "https://www.uniprot.org/uniprotkb/F1NRC6" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "F1NRC6", "url": "https://www.uniprot.org/uniprotkb/F1NRC6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "F1NRC6", "url": "https://www.uniprot.org/uniprotkb/F1NRC6" } ], "pmid": "" }, { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "F1NRC6", "url": "https://www.uniprot.org/uniprotkb/F1NRC6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 110, "end_pos": 112, "annotation": "n_glycosylation_sequon" }, { "start_pos": 119, "end_pos": 121, "annotation": "n_glycosylation_sequon" }, { "start_pos": 244, "end_pos": 246, "annotation": "n_glycosylation_sequon" }, { "start_pos": 342, "end_pos": 344, "annotation": "n_glycosylation_sequon" }, { "start_pos": 352, "end_pos": 354, "annotation": "n_glycosylation_sequon" }, { "start_pos": 38, "end_pos": 40, "annotation": "n_glycosylation_sequon" }, { "start_pos": 453, "end_pos": 455, "annotation": "n_glycosylation_sequon" }, { "start_pos": 573, "end_pos": 575, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-GGA-983140", "name": "Transfer of Ub from E2 to substrate and release of E2", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0X324-1", "A0A8V0XEM6-1", "A0A8V0XJC4-1", "A0A8V0XQR1-1", "A0A8V1AC19-1", "A0A8V1AC55-1", "A0A8V1AKB8-1", "A0A8V1ALH0-1", "F1NL19-1", "F1NRC6-1", "F1NTZ8-1", "A0A8V0YHL7-1", "A0A8V0YPW4-1", "A0A8V0YRM6-1", "A0A8V0YV22-1", "A0A8V0YVP3-1", "A0A8V0Z2L5-1", "F1NL77-1", "E1C982-1", "A0A3Q2UC96-1", "Q5ZKX6-1", "Z4YJC3-1", "A0A8V0XQU7-1", "A0A8V0Y5C9-1", "A0A8V1AL09-1", "A0A8V1AML5-1", "A0A8V1AP69-1", "F1NVY8-1", "R4GIV8-1", "A0A8V0ZJ49-1", "A0A8V0ZJV9-1", "A0A8V0ZL18-1", "A0A8V0ZM17-1", "A0A8V0ZSH4-1", "A0A8V0ZVX3-1", "A0A8V0ZW26-1", "A0A8V1A0Z6-1", "A0A8V0ZZH3-1", "A0A8V1A052-1", "A0A8V1A0X2-1", "A0A8V1A1I4-1", "A0A8V1A2W7-1", "A0A8V1A5P4-1", "A0A8V1A7T1-1", "A0A8V0XTY5-1", "A0A8V0Y5B5-1", "A0A8V0YL05-1", "A0A8V0Z082-1", "A0A8V0ZS27-1", "A0A8V1A9M0-1", "E1BZ35-1", "E1C3Q9-1", "F1NC08-1", "F1P2G0-1", "A0A8V0YY10-1", "A0A8V0YYC5-1", "A0A8V0Z1W7-1", "A0A8V0Z4C8-1", "A0A8V0Z596-1", "A0A1D5P284-1", "A0A8V0ZF21-1", "A0A3Q2U2G8-1", "A0A8V1A4H7-1", "A0A8V1A1N8-1", "A0A8V1A233-1", "A0A8V1A7P9-1", "A0A8V1ACU3-1", "A0A8V0ZSA3-1", "E1C656-1", "A0A8V0Y0Q7-1", "A0A8V0Y059-1", "A0A8V0Y5C7-1", "A0A8V0YCS7-1", "A0A8V0YDQ1-1", "A0A8V0YFD9-1", "A0A8V0YGF4-1", "A0A8V0YJK8-1", "A0A8V0YLY7-1", "A0A1D5NVE2-1", "A0A8V0ZKK3-1", "A0A8V0ZKQ3-1" ], "evidence": [ { "id": "R-GGA-983140", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983140" } ] }, { "id": "R-GGA-983147", "name": "Release of E3 from polyubiquitinated substrate", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XEM6-1", "A0A8V0XJC4-1", "A0A8V1AC55-1", "A0A8V1AKB8-1", "A0A8V1ALH0-1", "F1NRC6-1", "F1NTZ8-1", "A0A8V0YHL7-1", "A0A8V0YRM6-1", "A0A8V0YV22-1", "A0A8V0YVP3-1", "A0A8V0Z2L5-1", "F1NL77-1", "E1C982-1", "A0A3Q2UC96-1", "Z4YJC3-1", "A0A8V0XQU7-1", "A0A8V0Y5C9-1", "A0A8V1AL09-1", "A0A8V1AML5-1", "A0A8V1AP69-1", "F1NVY8-1", "A0A8V0ZJ49-1", "A0A8V0ZJV9-1", "A0A8V0ZL18-1", "A0A8V0ZM17-1", "A0A8V0ZSH4-1", "A0A8V0ZVX3-1", "A0A8V0ZW26-1", "A0A8V1A0Z6-1", "A0A8V0ZZH3-1", "A0A8V1A0X2-1", "A0A8V1A2W7-1", "A0A8V1A7T1-1", "A0A8V0XTY5-1", "A0A8V0Y5B5-1", "A0A8V0YL05-1", "A0A8V0ZS27-1", "A0A8V1A9M0-1", "E1BZ35-1", "E1C3Q9-1", "F1NC08-1", "F1P2G0-1", "A0A8V0YYC5-1", "A0A8V0Z4C8-1", "A0A8V0Z596-1", "A0A1D5P284-1", "A0A8V0ZF21-1", "A0A3Q2U2G8-1", "A0A8V1A1N8-1", "A0A8V1A233-1", "A0A8V1A7P9-1", "A0A8V0ZSA3-1", "E1C656-1", "A0A8V0Y0Q7-1", "A0A8V0Y5C7-1", "A0A8V0YCS7-1", "A0A8V0YDQ1-1", "A0A8V0YGF4-1", "A0A8V0YJK8-1", "A0A8V0YLY7-1", "A0A8V0ZKK3-1", "A0A8V0ZKQ3-1" ], "evidence": [ { "id": "R-GGA-983147", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983147" } ] }, { "id": "R-GGA-983156", "name": "Polyubiquitination of substrate", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0X324-1", "A0A8V0XEM6-1", "A0A8V0XJC4-1", "A0A8V0XQR1-1", "A0A8V1AC19-1", "A0A8V1AC55-1", "A0A8V1AKB8-1", "A0A8V1ALH0-1", "F1NL19-1", "F1NRC6-1", "F1NTZ8-1", "A0A8V0YHL7-1", "A0A8V0YPW4-1", "A0A8V0YRM6-1", "A0A8V0YV22-1", "A0A8V0YVP3-1", "A0A8V0Z2L5-1", "F1NL77-1", "E1C982-1", "A0A3Q2UC96-1", "Q5ZKX6-1", "Z4YJC3-1", "A0A8V0XQU7-1", "A0A8V0Y5C9-1", "A0A8V1AL09-1", "A0A8V1AML5-1", "A0A8V1AP69-1", "F1NVY8-1", "R4GIV8-1", "A0A8V0ZJ49-1", "A0A8V0ZJV9-1", "A0A8V0ZL18-1", "A0A8V0ZM17-1", "A0A8V0ZSH4-1", "A0A8V0ZVX3-1", "A0A8V0ZW26-1", "A0A8V1A0Z6-1", "A0A8V0ZZH3-1", "A0A8V1A052-1", "A0A8V1A0X2-1", "A0A8V1A1I4-1", "A0A8V1A2W7-1", "A0A8V1A5P4-1", "A0A8V1A7T1-1", "A0A8V0XTY5-1", "A0A8V0Y5B5-1", "A0A8V0YL05-1", "A0A8V0Z082-1", "A0A8V0ZS27-1", "A0A8V1A9M0-1", "E1BZ35-1", "E1C3Q9-1", "F1NC08-1", "F1P2G0-1", "A0A8V0YY10-1", "A0A8V0YYC5-1", "A0A8V0Z1W7-1", "A0A8V0Z4C8-1", "A0A8V0Z596-1", "A0A1D5P284-1", "A0A8V0ZF21-1", "A0A3Q2U2G8-1", "A0A8V1A4H7-1", "A0A8V1A1N8-1", "A0A8V1A233-1", "A0A8V1A7P9-1", "A0A8V1ACU3-1", "A0A8V0ZSA3-1", "E1C656-1", "A0A8V0Y0Q7-1", "A0A8V0Y059-1", "A0A8V0Y5C7-1", "A0A8V0YCS7-1", "A0A8V0YDQ1-1", "A0A8V0YFD9-1", "A0A8V0YGF4-1", "A0A8V0YJK8-1", "A0A8V0YLY7-1", "A0A1D5NVE2-1", "A0A8V0ZKK3-1", "A0A8V0ZKQ3-1" ], "evidence": [ { "id": "R-GGA-983156", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983156" } ] }, { "id": "R-GGA-983157", "name": "Interaction of E3 with substrate and E2-Ub complex", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0X324-1", "A0A8V0XEM6-1", "A0A8V0XJC4-1", "A0A8V0XQR1-1", "A0A8V1AC19-1", "A0A8V1AC55-1", "A0A8V1AKB8-1", "A0A8V1ALH0-1", "F1NL19-1", "F1NRC6-1", "F1NTZ8-1", "A0A8V0YHL7-1", "A0A8V0YPW4-1", "A0A8V0YRM6-1", "A0A8V0YV22-1", "A0A8V0YVP3-1", "A0A8V0Z2L5-1", "F1NL77-1", "E1C982-1", "A0A3Q2UC96-1", "Q5ZKX6-1", "Z4YJC3-1", "A0A8V0XQU7-1", "A0A8V0Y5C9-1", "A0A8V1AL09-1", "A0A8V1AML5-1", "A0A8V1AP69-1", "F1NVY8-1", "R4GIV8-1", "A0A8V0ZJ49-1", "A0A8V0ZJV9-1", "A0A8V0ZL18-1", "A0A8V0ZM17-1", "A0A8V0ZSH4-1", "A0A8V0ZVX3-1", "A0A8V0ZW26-1", "A0A8V1A0Z6-1", "A0A8V0ZZH3-1", "A0A8V1A052-1", "A0A8V1A0X2-1", "A0A8V1A1I4-1", "A0A8V1A2W7-1", "A0A8V1A5P4-1", "A0A8V1A7T1-1", "A0A8V0XTY5-1", "A0A8V0Y5B5-1", "A0A8V0YL05-1", "A0A8V0Z082-1", "A0A8V0ZS27-1", "A0A8V1A9M0-1", "E1BZ35-1", "E1C3Q9-1", "F1NC08-1", "F1P2G0-1", "A0A8V0YY10-1", "A0A8V0YYC5-1", "A0A8V0Z1W7-1", "A0A8V0Z4C8-1", "A0A8V0Z596-1", "A0A1D5P284-1", "A0A8V0ZF21-1", "A0A3Q2U2G8-1", "A0A8V1A4H7-1", "A0A8V1A1N8-1", "A0A8V1A233-1", "A0A8V1A7P9-1", "A0A8V1ACU3-1", "A0A8V0ZSA3-1", "E1C656-1", "A0A8V0Y0Q7-1", "A0A8V0Y059-1", "A0A8V0Y5C7-1", "A0A8V0YCS7-1", "A0A8V0YDQ1-1", "A0A8V0YFD9-1", "A0A8V0YGF4-1", "A0A8V0YJK8-1", "A0A8V0YLY7-1", "A0A1D5NVE2-1", "A0A8V0ZKK3-1", "A0A8V0ZKQ3-1" ], "evidence": [ { "id": "R-GGA-983157", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983157" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A1D5NVE2", "gene_name": "UBE2Q1", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A1D5NVE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NVE2" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A1D5NVE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NVE2" } ] } ] }, { "uniprot_ac": "A0A1D5P284", "gene_name": "UBR2", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A1D5P284", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P284" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A1D5P284", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P284" } ] } ] }, { "uniprot_ac": "A0A3Q2U2G8", "gene_name": "TRIM9", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A3Q2U2G8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U2G8" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A3Q2U2G8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U2G8" } ] } ] }, { "uniprot_ac": "A0A3Q2UC96", "gene_name": "NEDD4L", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A3Q2UC96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UC96" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A3Q2UC96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UC96" } ] } ] }, { "uniprot_ac": "A0A8V0X324", "gene_name": "UBE2E1", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V0X324", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X324" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V0X324", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X324" } ] } ] }, { "uniprot_ac": "A0A8V0XEM6", "gene_name": "HERC2", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0XEM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEM6" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0XEM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEM6" } ] } ] }, { "uniprot_ac": "A0A8V0XJC4", "gene_name": "UBE3D", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0XJC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XJC4" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0XJC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XJC4" } ] } ] }, { "uniprot_ac": "A0A8V0XQR1", "gene_name": "UBE2H", "activity": [ { "ec_number": "2.3.2.24", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E1 ubiquitin-activating enzyme]-L-cysteine + N(6)-monoubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0XQR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQR1" } ] }, { "ec_number": "2.3.2.24", "activity": "", "evidence": [ { "id": "A0A8V0XQR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQR1" } ] } ] }, { "uniprot_ac": "A0A8V0XQU7", "gene_name": "RNF6", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0XQU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQU7" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0XQU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQU7" } ] } ] }, { "uniprot_ac": "A0A8V0XTY5", "gene_name": "SH3RF1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0XTY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XTY5" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0XTY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XTY5" } ] } ] }, { "uniprot_ac": "A0A8V0Y059", "gene_name": "UBE2D1", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V0Y059", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y059" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V0Y059", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y059" } ] } ] }, { "uniprot_ac": "A0A8V0Y0Q7", "gene_name": "RNF144B", "activity": [ { "ec_number": "2.3.2.31", "activity": "[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-N(6)-ubiquitinyl-L-lysine.", "evidence": [ { "id": "A0A8V0Y0Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y0Q7" } ] }, { "ec_number": "2.3.2.31", "activity": "", "evidence": [ { "id": "A0A8V0Y0Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y0Q7" } ] } ] }, { "uniprot_ac": "A0A8V0Y5B5", "gene_name": "LTN1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0Y5B5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5B5" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0Y5B5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5B5" } ] } ] }, { "uniprot_ac": "A0A8V0Y5C7", "gene_name": "CBLL1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0Y5C7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5C7" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0Y5C7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5C7" } ] } ] }, { "uniprot_ac": "A0A8V0Y5C9", "gene_name": "HERC3", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0Y5C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5C9" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0Y5C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5C9" } ] } ] }, { "uniprot_ac": "A0A8V0YCS7", "gene_name": "RNF19A", "activity": [ { "ec_number": "2.3.2.31", "activity": "[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-N(6)-ubiquitinyl-L-lysine.", "evidence": [ { "id": "A0A8V0YCS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCS7" } ] }, { "ec_number": "2.3.2.31", "activity": "", "evidence": [ { "id": "A0A8V0YCS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCS7" } ] } ] }, { "uniprot_ac": "A0A8V0YDQ1", "gene_name": "WWP1", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YDQ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDQ1" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0YDQ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDQ1" } ] } ] }, { "uniprot_ac": "A0A8V0YFD9", "gene_name": "UBE2D2", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V0YFD9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFD9" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V0YFD9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFD9" } ] } ] }, { "uniprot_ac": "A0A8V0YGF4", "gene_name": "MYLIP", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YGF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGF4" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0YGF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGF4" } ] } ] }, { "uniprot_ac": "A0A8V0YHL7", "gene_name": "RNF114", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YHL7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHL7" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0YHL7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHL7" } ] } ] }, { "uniprot_ac": "A0A8V0YJK8", "gene_name": "RNF14", "activity": [ { "ec_number": "2.3.2.31", "activity": "[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-N(6)-ubiquitinyl-L-lysine.", "evidence": [ { "id": "A0A8V0YJK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJK8" } ] }, { "ec_number": "2.3.2.31", "activity": "", "evidence": [ { "id": "A0A8V0YJK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJK8" } ] } ] }, { "uniprot_ac": "A0A8V0YL05", "gene_name": "UBE3A", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YL05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL05" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0YL05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL05" } ] } ] }, { "uniprot_ac": "A0A8V0YLY7", "gene_name": "MKRN4P", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YLY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLY7" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0YLY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLY7" } ] } ] }, { "uniprot_ac": "A0A8V0YPW4", "gene_name": "UBE2J2", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V0YPW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPW4" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V0YPW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPW4" } ] } ] }, { "uniprot_ac": "A0A8V0YRM6", "gene_name": "RNF130", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YRM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRM6" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0YRM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRM6" } ] } ] }, { "uniprot_ac": "A0A8V0YV22", "gene_name": "RNF4", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YV22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YV22" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0YV22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YV22" } ] } ] }, { "uniprot_ac": "A0A8V0YVP3", "gene_name": "RBBP6", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YVP3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YVP3" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0YVP3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YVP3" } ] } ] }, { "uniprot_ac": "A0A8V0YY10", "gene_name": "UBE2D3", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V0YY10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YY10" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V0YY10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YY10" } ] } ] }, { "uniprot_ac": "A0A8V0YYC5", "gene_name": "ZNRF2", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YYC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYC5" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0YYC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYC5" } ] } ] }, { "uniprot_ac": "A0A8V0Z082", "gene_name": "UBE2B", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V0Z082", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z082" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V0Z082", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z082" } ] } ] }, { "uniprot_ac": "A0A8V0Z1W7", "gene_name": "UBE2K", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V0Z1W7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1W7" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V0Z1W7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1W7" } ] } ] }, { "uniprot_ac": "A0A8V0Z2L5", "gene_name": "TRIM63", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0Z2L5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2L5" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0Z2L5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2L5" } ] } ] }, { "uniprot_ac": "A0A8V0Z4C8", "gene_name": "MGRN1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0Z4C8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4C8" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0Z4C8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4C8" } ] } ] }, { "uniprot_ac": "A0A8V0Z596", "gene_name": "STUB1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0Z596", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z596" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0Z596", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z596" } ] } ] }, { "uniprot_ac": "A0A8V0ZF21", "gene_name": "DTX3L", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZF21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF21" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0ZF21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF21" } ] } ] }, { "uniprot_ac": "A0A8V0ZJ49", "gene_name": "SMURF1", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZJ49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ49" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0ZJ49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ49" } ] } ] }, { "uniprot_ac": "A0A8V0ZJV9", "gene_name": "MIB2", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZJV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJV9" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0ZJV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJV9" } ] } ] }, { "uniprot_ac": "A0A8V0ZKK3", "gene_name": "UBE3B", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZKK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKK3" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0ZKK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKK3" } ] } ] }, { "uniprot_ac": "A0A8V0ZKQ3", "gene_name": "RNF25", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZKQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKQ3" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0ZKQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKQ3" } ] } ] }, { "uniprot_ac": "A0A8V0ZL18", "gene_name": "HECTD2", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZL18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZL18" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0ZL18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZL18" } ] } ] }, { "uniprot_ac": "A0A8V0ZM17", "gene_name": "UBR1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZM17", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM17" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0ZM17", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM17" } ] } ] }, { "uniprot_ac": "A0A8V0ZS27", "gene_name": "TRIP12", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZS27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS27" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0ZS27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS27" } ] } ] }, { "uniprot_ac": "A0A8V0ZSA3", "gene_name": "HERC4", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZSA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSA3" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0ZSA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSA3" } ] } ] }, { "uniprot_ac": "A0A8V0ZSH4", "gene_name": "RNF111", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZSH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSH4" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0ZSH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSH4" } ] } ] }, { "uniprot_ac": "A0A8V0ZVX3", "gene_name": "NEDD4", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZVX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVX3" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0ZVX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVX3" } ] } ] }, { "uniprot_ac": "A0A8V0ZW26", "gene_name": "ZNRF1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZW26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZW26" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0ZW26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZW26" } ] } ] }, { "uniprot_ac": "A0A8V0ZZH3", "gene_name": "ITCH", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZZH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZH3" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0ZZH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZH3" } ] } ] }, { "uniprot_ac": "A0A8V1A052", "gene_name": "UBE2E3", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V1A052", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A052" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V1A052", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A052" } ] } ] }, { "uniprot_ac": "A0A8V1A0X2", "gene_name": "UBE3C", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1A0X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0X2" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V1A0X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0X2" } ] } ] }, { "uniprot_ac": "A0A8V1A0Z6", "gene_name": "UBE4A", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1A0Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0Z6" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1A0Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0Z6" } ] } ] }, { "uniprot_ac": "A0A8V1A1I4", "gene_name": "UBE2Z", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V1A1I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1I4" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V1A1I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1I4" } ] } ] }, { "uniprot_ac": "A0A8V1A1N8", "gene_name": "HERC1", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1A1N8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1N8" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V1A1N8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1N8" } ] } ] }, { "uniprot_ac": "A0A8V1A233", "gene_name": "RNF220", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1A233", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A233" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1A233", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A233" } ] } ] }, { "uniprot_ac": "A0A8V1A2W7", "gene_name": "RNF41", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1A2W7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2W7" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1A2W7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2W7" } ] } ] }, { "uniprot_ac": "A0A8V1A4H7", "gene_name": "UBE2L3", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V1A4H7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4H7" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V1A4H7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4H7" } ] } ] }, { "uniprot_ac": "A0A8V1A5P4", "gene_name": "UBE2G2", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V1A5P4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5P4" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V1A5P4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5P4" } ] } ] }, { "uniprot_ac": "A0A8V1A7P9", "gene_name": "DCAF1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A7P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P9" } ] } ] }, { "uniprot_ac": "A0A8V1A7T1", "gene_name": "RNF123", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1A7T1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7T1" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1A7T1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7T1" } ] } ] }, { "uniprot_ac": "A0A8V1A9M0", "gene_name": "RNF34", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1A9M0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9M0" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1A9M0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9M0" } ] } ] }, { "uniprot_ac": "A0A8V1AC19", "gene_name": "UBA7", "activity": [ { "ec_number": "6.2.1.45", "activity": "ATP + ubiquitin + [E1 ubiquitin-activating enzyme]-L-cysteine = AMP + diphosphate + S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V1AC19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC19" } ] }, { "ec_number": "6.2.1.45", "activity": "", "evidence": [ { "id": "A0A8V1AC19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC19" } ] } ] }, { "uniprot_ac": "A0A8V1AC55", "gene_name": "SMURF2", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1AC55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC55" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V1AC55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC55" } ] } ] }, { "uniprot_ac": "A0A8V1ACU3", "gene_name": "UBE2O", "activity": [ { "ec_number": "2.3.2.24", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E1 ubiquitin-activating enzyme]-L-cysteine + N(6)-monoubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1ACU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACU3" } ] }, { "ec_number": "2.3.2.24", "activity": "", "evidence": [ { "id": "A0A8V1ACU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACU3" } ] } ] }, { "uniprot_ac": "A0A8V1AKB8", "gene_name": "TRIM32", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1AKB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKB8" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1AKB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKB8" } ] } ] }, { "uniprot_ac": "A0A8V1AL09", "gene_name": "TRIM37", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1AL09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL09" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1AL09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL09" } ] } ] }, { "uniprot_ac": "A0A8V1ALH0", "gene_name": "RNF213", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1ALH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALH0" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1ALH0", "database": "UniProtKB", "url": 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"name": "GPR55", "type": "recommended", "evidence": [ { "id": "F1NRF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NRF0" } ] }, { "name": "GPR55", "type": "synonym", "evidence": [ { "id": "XP_046754524", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046754524" } ] } ], "protein_names": [ { "name": "G protein-coupled receptor 55", "type": "synonym", "evidence": [ { "id": "F1NRF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NRF0/entry#names_and_taxonomy" } ] }, { "name": "G-protein coupled receptor 55", "type": "synonym", "evidence": [ { "id": "XP_046754524", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046754524" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052540.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_046754524", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046754524" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NRF0", "url": "https://www.uniprot.org/uniprotkb/F1NRF0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "GPR55", "url": "https://www.uniprot.org/uniprotkb/F1NRF0", "locus": { "chromosome": "9", "start_pos": 5024969, "end_pos": 5002708, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010025664", "url": "https://www.ensembl.org/id/ENSGALG00010025664" } ] } } ], "crossref": [ { "id": "F1NRF0", "url": "https://alphafold.ebi.ac.uk/entry/F1NRF0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000005544", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000005544", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "124417087", "url": "https://www.ncbi.nlm.nih.gov/gene/124417087", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:770641", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:770641", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "TCFHNMS", "url": "https://omabrowser.org/oma/group/TCFHNMS/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1NRF0", "url": "https://www.orthodb.org/?gene=F1NRF0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24232", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24232", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24232:SF56", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24232:SF56", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00001", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00001", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-373076", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-373076", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-418594", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-418594", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_046754524", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046754524", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1NRF0", "url": "https://www.uniprot.org/uniprotkb/F1NRF0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NRF0-1", "url": "https://www.uniprot.org/uniprotkb/F1NRF0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTNISGECNFTSIDRLAETLRFGISIPTFILGLVLNTLALSVFCCFWKKQTKTSIYMINLALADVLLLLSLPLKLHYSVAEAPGLLCAFIQSLYFVNTYGSIFIIVCITVDRYICLKHPFEGRANQSPRWAILICCFIWAVTWLCSSPIYVFQKKDSLKCFHNMSDEAWSVPLIVSVEIFGFLIPLSVMVFCSAQNIWILLNHKNRAKEKADSLRVIIINLVVFLVCFTPVHLAICLQCLVRQHVIVDCRLKQTISLFIQLSMILANLNCCLDAIFYYFAAKEFREKTHLKKIIERCPVFKPCAT", "length": 305, "header": "tr|F1NRF0-1|F1NRF0_CHICK Isoform 1 of G protein-coupled receptor 55 OS=Gallus gallus OX=9031 GN=GPR55 PE=3 SV=2 CANONICAL=F1NRF0-1" }, "isoforms": [ { "isoform_ac": "F1NRF0-1", "url": "https://www.uniprot.org/uniprotkb/F1NRF0/entry#F1NRF0-1", "sequence": { "sequence": "MTNISGECNFTSIDRLAETLRFGISIPTFILGLVLNTLALSVFCCFWKKQTKTSIYMINLALADVLLLLSLPLKLHYSVAEAPGLLCAFIQSLYFVNTYGSIFIIVCITVDRYICLKHPFEGRANQSPRWAILICCFIWAVTWLCSSPIYVFQKKDSLKCFHNMSDEAWSVPLIVSVEIFGFLIPLSVMVFCSAQNIWILLNHKNRAKEKADSLRVIIINLVVFLVCFTPVHLAICLQCLVRQHVIVDCRLKQTISLFIQLSMILANLNCCLDAIFYYFAAKEFREKTHLKKIIERCPVFKPCAT", "length": 305, "header": "tr|F1NRF0-1|F1NRF0_CHICK Isoform 1 of G protein-coupled receptor 55 OS=Gallus gallus OX=9031 GN=GPR55 PE=3 SV=2 CANONICAL=F1NRF0-1" }, "locus": { "chromosome": "9", "start_pos": 5015697, "end_pos": 5014783, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010062641.1", "url": "https://www.ensembl.org/id/ENSGALT00010062641.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038730.1", "url": "https://www.ensembl.org/id/ENSGALP00010038730.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:770641", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:770641", "resource": "KEGG Pathway" }, { "id": "R-GGA-373076", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-373076", "resource": "Reactome", "description": "Class A/1 (Rhodopsin-like receptors)" }, { "id": "R-GGA-418594", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-418594", "resource": "Reactome", "description": "G alpha (i) signalling events" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287A4Z4-1", "protein_name": "G protein-coupled receptor 55", "gene_name": "GPR55", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRKLSPREGSDSPQSRLVTKLGGEMTSHSLLSCTGPPTGKNMNQLNQSKDCNFNDVDKLMKTVQMTVNIPTFLLGLLLNLLAIRGFSSFLKKRWPYYAATSIYMINLAVFDLLLVLSLPFKMALSHVKAPFLPFCTLVECLYFISMYGSIFTICFISLDRFLAIRYPLLVSHLRSPRKVLGICCIIWVLLWVGSTPVYSFHQKEENYTCFHNLSDGTWSVKVLLPLEVFGFLLPMSIMGFCSSRSICILVRRRNHTQDWVQQKTCIWTIAANLVVFVVSFLPVHLSFFLQFLVRNGFIMECRTRQNISLFVQLSMCFSNFNCCLDVFCYYFVIKEFRMDIMTHHRPSRVQVVRQDTMTTRG", "length": 361 }, "evidence": [ { "id": "F1NRF0", "url": "https://omabrowser.org/oma/group/F1NRF0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0AAA9SNQ9-1", "protein_name": "G protein-coupled receptor 55", "gene_name": "GPR55", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSQQNHSENCSFNDVKQLMETVQLAVHIPTFILGLLLNVLAIRGFSSFLKKRWPCYTATSIYMINLAVFDLLLVLSLPFKMFLSRRQGSFLPFCTLVECLYFISMYGSIFTICFISLDRFLAIRYPILVSHIRSPRKIFGICCIIWVLVWVGSTPVYSFHGKVQNYTCFNNMTDGTWSAKVFFPFEVFGFLLPMSIIGFCSSRSIHILVARRDHTRDWVQQKACIWTIAVSLAVFVVSFLPVHLSFFLQFLVRNGFIVECRAKQNIILFLQLSMCFSNFNCCLDVFCYYFVIKEFRMDIMAHRPSRSQLVHQDTLTTMAKGKKSCLEEGNLNLNSIVNIPSQGPDVVG", "length": 348 }, "evidence": [ { "id": "F1NRF0", "url": "https://omabrowser.org/oma/group/F1NRF0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1MAK4-1", "protein_name": "G protein-coupled receptor 55", "gene_name": "Gpr55", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSQLDSNNCSFVFVDNLTKTLQLAVHIPTFLLGLVLNLLAIRGFGAFLKRRQLEYMATSIYMINLAVFDLLLVLSLPFKMILPQVKSSPSLVFCTFVECLYFISMYGSVFTICFISLDRLLAIQYPLLVNHFRSPRKTFGICCIIWMLVWVGSIPIYTFHRGVEGYKCFHNMSDSTWSARVFFPLEIFGFLLPMGIMGFCSYRSIHILLSIQGDDQWVRKRACIIWTIATNLVVFVVSFLPVHLGLFLQFLVRNGFILNCRVKQGISLFLQLSLCFSNINCCLDVFCYYFAIKEFRMGIKVHRPSQVQLVHQDSMVSRA", "length": 319 }, "evidence": [ { "id": "F1NRF0", "url": "https://omabrowser.org/oma/group/F1NRF0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3IH69-1", "protein_name": "G-protein coupled receptor 55", "gene_name": "Gpr55", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSRPYASDNCSFDDVDKLMSTLQLAVHIPTFLLGLVLNLLAIRGFSTFLKKKQLEYIATSIYMINLAVFDLLLVLSLPFKMALPQVESPPQVFCTLVECLYFISMYGSIFTICFISVDRFLAIQYPLLVNHLRSPRKAFGICCSLWILVWVGSIPIYTFHREVEKYKCFHNMSDGTWSAKVFFPLEIFGFLLPMGIMGFCSYRIIHILLRCRNPVQQRACIWTIATNLVIFVVSFLPVHLGFFLQFLVRNGFIVECRAKQNISLFLQLSLCFSNINCCLDVFCYYFVIKEFRMGIKGPQASTVELVRQDTMISRGYGEVPLSKEGDPSPEFS", "length": 332 }, "evidence": [ { "id": "F1NRF0", "url": "https://omabrowser.org/oma/group/F1NRF0/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q3UJF0-1", "protein_name": "G protein-coupled receptor 55", "gene_name": "Gpr55", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSQPERDNCSFDSVDKLTRTLQLAVHIPTFLLGLVLNLLAIRGFSAFLKKRKLDYIATSIYMINLAVFDLLLVLSLPFKMVLPQVESPLPSFCTLVECLYFISMYGSVFTICFISLDRFLAIQYPILASHLRSPRKTFGICCIIWMLVWIGSIPIYTFHREVERYKCFHNMSDVTWSASVFFPLEIFGFLLPMGIMGFCSYRSIHILLRRPDSTEDWVQQRDTKGWVQKRACIWTIATNLVIFVVSFLPVHLGFFLQYLVRNRFILDCRMKQGISLFLQLSLCFSNINCCLDVFCYYFVIKEFRMRIKAHRPSTIKLVNQDTMVSRG", "length": 327 }, "evidence": [ { "id": "F1NRF0", "url": "https://omabrowser.org/oma/group/F1NRF0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9Y2T6-1", "protein_name": "G protein-coupled receptor 55", "gene_name": "GPR55", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSQQNTSGDCLFDGVNELMKTLQFAVHIPTFVLGLLLNLLAIHGFSTFLKNRWPDYAATSIYMINLAVFDLLLVLSLPFKMVLSQVQSPFPSLCTLVECLYFVSMYGSVFTICFISMDRFLAIRYPLLVSHLRSPRKIFGICCTIWVLVWTGSIPIYSFHGKVEKYMCFHNMSDDTWSAKVFFPLEVFGFLLPMGIMGFCCSRSIHILLGRRDHTQDWVQQKACIYSIAASLAVFVVSFLPVHLGFFLQFLVRNSFIVECRAKQSISFFLQLSMCFSNVNCCLDVFCYYFVIKEFRMNIRAHRPSRVQLVLQDTTISRG", "length": 319 }, "evidence": [ { "id": "F1NRF0", "url": "https://omabrowser.org/oma/group/F1NRF0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F1NRF0", "url": "https://www.uniprot.org/uniprotkb/F1NRF0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "G protein-coupled receptor signaling pathway", "id": "GO:0007186", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007186", "evidence": [ { "database": "UniProtKB", "id": "F1NRF0", "url": "https://www.uniprot.org/uniprotkb/F1NRF0" } ], "pmid": "" }, { "name": "positive regulation of ERK1 and ERK2 cascade", "id": "GO:0070374", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070374", "evidence": [ { "database": "UniProtKB", "id": "F1NRF0", "url": "https://www.uniprot.org/uniprotkb/F1NRF0" } ], "pmid": "" }, { "name": "phospholipase C-activating G protein-coupled receptor signaling pathway", "id": "GO:0007200", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007200", "evidence": [ { "database": "UniProtKB", "id": "F1NRF0", "url": "https://www.uniprot.org/uniprotkb/F1NRF0" } ], "pmid": "" }, { "name": "bone resorption", "id": "GO:0045453", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045453", "evidence": [ { "database": "UniProtKB", "id": "F1NRF0", "url": "https://www.uniprot.org/uniprotkb/F1NRF0" } ], "pmid": "" }, { "name": "positive regulation of Rho protein 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}, { "start_pos": 3, "end_pos": 5, "annotation": "n_glycosylation_sequon" }, { "start_pos": 9, "end_pos": 11, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1NRF0-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 305, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1NRF0-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1NRF0" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1NRF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NRF0" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 35, "end_pos": 277, "start_aa": "Leu", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 125, "end_pos": 127 }, { "start_pos": 163, "end_pos": 165 }, { "start_pos": 3, "end_pos": 5 }, { "start_pos": 9, "end_pos": 11 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", 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Gap junctions are dodecameric channels that connect the cytoplasm of adjoining cells. They are formed by the docking of two hexameric hemichannels, one from each cell membrane. Small molecules and ions diffuse from one cell to a neighboring cell via the central pore.", "evidence": [ { "database": "UniProtKB", "id": "F1NRH7", "url": "https://www.uniprot.org/uniprotkb/F1NRH7#function" }, { "database": "UniProtKB", "id": "ARBA00045956", "url": "https://www.uniprot.org/uniprotkb/ARBA00045956#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NRH7", "url": "https://www.uniprot.org/uniprotkb/F1NRH7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "GJA8", "url": "https://www.uniprot.org/uniprotkb/F1NRH7", "locus": { "chromosome": "1", "start_pos": 92665696, "end_pos": 92584607, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010008002", "url": "https://www.ensembl.org/id/ENSGALG00010008002" } ] } } ], "crossref": [ { "id": "ENSGALG00000015488", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000015488", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "395846", "url": "https://www.ncbi.nlm.nih.gov/gene/395846", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000500", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000500", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002266", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002266", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013092", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013092", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017990", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017990", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019570", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019570", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038359", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038359", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:395846", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:395846", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "EKPVSHY", "url": "https://omabrowser.org/oma/group/EKPVSHY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1NRH7", "url": "https://www.orthodb.org/?gene=F1NRH7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11984", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11984", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11984:SF19", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11984:SF19", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00029", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00029", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF03509", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03509", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-190861", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-190861", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_990328", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990328", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1NRH7", "url": "https://www.uniprot.org/uniprotkb/F1NRH7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NRH7-1", "url": "https://www.uniprot.org/uniprotkb/F1NRH7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGDWSFLGNILEQVNEQSTVIGRVWLTVLFIFRILILGTAAELVWGDEQSDFVCNTQQPGCENVCYDEAFPISHIRLWVLQIIFVSTPSLVYFGHAVHHVRMEEKRKEREEAERRQQTEVDEEKLPLAPNQNKGNNPDGTKKFRLEGTLLRTYILHIIFKTLFEVGFIVGQYFLYGFRILPLYRCGRWPCPNLVDCFVSRPTEKTIFIMFMLVVAAVSLFLNLVEISHLILKRIRRALRRPAEEQMGEVPEKPLHAIAVSSIPKAKGYKLLEEEKPVSHYFPLTEVGVEPSPLPSAFNEFEEKIGMGPLEDLSRAFDERLPSYAQAKEPEEEKVKAEEEEEQEEEQQAPQEEPGVKKAEEEVVSDEVEGPSAPAELATDVRSLSRLSKASSRARSDDLTV", "length": 400, "header": "tr|F1NRH7-1|F1NRH7_CHICK Isoform 1 of Gap junction protein OS=Gallus gallus OX=9031 GN=GJA8 PE=3 SV=1 CANONICAL=F1NRH7-1" }, "isoforms": [ { "isoform_ac": "F1NRH7-1", "url": "https://www.uniprot.org/uniprotkb/F1NRH7/entry#F1NRH7-1", "sequence": { "sequence": "MGDWSFLGNILEQVNEQSTVIGRVWLTVLFIFRILILGTAAELVWGDEQSDFVCNTQQPGCENVCYDEAFPISHIRLWVLQIIFVSTPSLVYFGHAVHHVRMEEKRKEREEAERRQQTEVDEEKLPLAPNQNKGNNPDGTKKFRLEGTLLRTYILHIIFKTLFEVGFIVGQYFLYGFRILPLYRCGRWPCPNLVDCFVSRPTEKTIFIMFMLVVAAVSLFLNLVEISHLILKRIRRALRRPAEEQMGEVPEKPLHAIAVSSIPKAKGYKLLEEEKPVSHYFPLTEVGVEPSPLPSAFNEFEEKIGMGPLEDLSRAFDERLPSYAQAKEPEEEKVKAEEEEEQEEEQQAPQEEPGVKKAEEEVVSDEVEGPSAPAELATDVRSLSRLSKASSRARSDDLTV", "length": 400, "header": "tr|F1NRH7-1|F1NRH7_CHICK Isoform 1 of Gap junction protein OS=Gallus gallus OX=9031 GN=GJA8 PE=3 SV=1 CANONICAL=F1NRH7-1" }, "locus": { "chromosome": "1", "start_pos": 92657535, "end_pos": 92656336, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010019073.1", "url": "https://www.ensembl.org/id/ENSGALT00010019073.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010010622.1", "url": "https://www.ensembl.org/id/ENSGALP00010010622.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:395846", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:395846", "resource": "KEGG Pathway" }, { "id": "R-GGA-190861", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-190861", "resource": "Reactome", "description": "Gap junction assembly" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287AYS5-1", "protein_name": "Gap junction protein", "gene_name": "GJA8", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGDWSFLGNILEEVNEHSTVIGRVWLTVLFIFRILILGTAAEFVWGDEQSDFVCNTQQPGCENVCYDEAFPISHIRLWVLQIIFVSTPSLVYVGHAVHHVRMEEKRKEREAEELGQQGDGGERAPLAADQGSNKKSGGSGKGAKKFRLEGTLLRTYICHIIFKTLFEVGFVVGHYFLYGFRILPLYRCSRWPCPNVVDCFVSRPTEKTIFILFMLSVASVSLFLNILEMSHLGLKRIRSALKKPAEQPLGEVPEKSLHSIAVSSIQKAKGYQLLEEEKIVSHYFPLTEVGIVETSPLSAKPFSQFEEKMGTGPLGDLSRAYQETLPSYAQVGAQEGAQEGEGEEQPVEEGAEPEVGEKRQEEERVSTEGQEVVAVLEAEKAETPEVGEEEVEPEELQPEEITKQEVPAEKAPSLCPELPGDDSRPLSRLSKASSRARSDDLTV", "length": 443 }, "evidence": [ { "id": "F1NRH7", "url": "https://omabrowser.org/oma/group/F1NRH7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1MHI7-1", "protein_name": "Gap junction protein", "gene_name": "GJA8", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGDWSFLGNILEEVNEHSTVIGRVWLTVLFIFRILILGTAAEFVWGDEQSDFVCNTQQPGCENVCYDEAFPISHIRLWVLQIIFVSTPSLVYVGHAVHHVRMEEKRKEREAEELSQQSPGNGGERAPLAADQGSVKKSSSSSKGTKKFRLEGTLLRTYICHIIFKTLFEVGFIVGHYFLYGFRILPLYRCSRWPCPNVVDCFVSRPTEKTIFILFMLSVASVSLFLNILEMSHLGLKKIRSAFKRPVEQPLGEIPEKSLHSIAVSSIQKAKGYQLLEEEKIVSHYFPLTEVGMVEASPLSAKPFSQFEEKVGPGPLGDLSRAYQETLPSYAQVGAQEGVEEEQPVEAAAEPEVGEKSQEAERVSTEGQETLAVLEVEKVEPPEVEKEVEKEEPPPEKVSKQELTPEKAPSLCAELPGDDTRPLSRLSKTSSRARSDDLTV", "length": 440 }, "evidence": [ { "id": "F1NRH7", "url": "https://omabrowser.org/oma/group/F1NRH7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "G3H2R1-1", "protein_name": "Gap junction protein", "gene_name": "Gja8", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MGDWSFLGNILEEVNEHSTVIGRVWLTVLFIFRILILGTAAEFVWGDEQSDFVCNTQQPGCENVCYDEAFPISHIRLWVLQIIFVSTPSLMYVGHAVHHVRMEEKRKDREAEELCQQSRSNGGERVPIAPDQASIRKSSSSSKGTKKFRLEGTLLRTYVCHIIFKTLFEVGFIVGHYFLYGFRILPLYRCSRWPCPNVVDCFVSRPTEKTIFILFMLSVAFVSLFLNIMEMSHLGMKGIRSAFKRPVEQPLGEIPEKSLHSIAVSSIQKAKGYQLLEEEKIVSHYFPLTEVGMVETSPLSAKPFSQFEEKIGTGPLADMSRGYQETLPSYAQVGAQEVEGDAQPVEEAVEMGEKKIEAEKVTPEEQETVVVPDGEKVETPGVGKDGEKEELQAEKVAKQGLSAEKAPSLCPELTTDDNRPLSRLSKASSRARSDDLTI", "length": 438 }, "evidence": [ { "id": "F1NRH7", "url": "https://omabrowser.org/oma/group/F1NRH7/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P28236-1", "protein_name": "Gap junction alpha-8 protein", "gene_name": "Gja8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGDWSFLGNILEEVNEHSTVIGRVWLTVLFIFRILILGTAAEFVWGDEQSDFVCNTQQPGCENVCYDEAFPISHIRLWVLQIIFVSTPSLMYVGHAVHHVRMEEKRKDREAEELCQQSRSNGGERVPIAPDQASIRKSSSSSKGTKKFRLEGTLLRTYVCHIIFKTLFEVGFIVGHYFLYGFRILPLYRCSRWPCPNVVDCFVSRPTEKTIFILFMLSVAFVSLFLNIMEMSHLGMKGIRSAFKRPVEQPLGEIAEKSLHSIAVSSIQKAKGYQLLEEEKIVSHYFPLTEVGMVETSPLSAKPFSQFEEKIGTGPLADMSRSYQETLPSYAQVGVQEVEREEPPIEEAVEPEVGEKKQEAEKVAPEGQETVAVPDRERVETPGVGKEDEKEELQAEKVTKQGLSAEKAPSLCPELTTDDNRPLSRLSKASSRARSDDLTI", "length": 440 }, "evidence": [ { "id": "F1NRH7", "url": "https://omabrowser.org/oma/group/F1NRH7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P48165-1", "protein_name": "Gap junction alpha-8 protein", "gene_name": "GJA8", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGDWSFLGNILEEVNEHSTVIGRVWLTVLFIFRILILGTAAEFVWGDEQSDFVCNTQQPGCENVCYDEAFPISHIRLWVLQIIFVSTPSLMYVGHAVHYVRMEEKRKSREAEELGQQAGTNGGPDQGSVKKSSGSKGTKKFRLEGTLLRTYICHIIFKTLFEVGFIVGHYFLYGFRILPLYRCSRWPCPNVVDCFVSRPTEKTIFILFMLSVASVSLFLNVMELGHLGLKGIRSALKRPVEQPLGEIPEKSLHSIAVSSIQKAKGYQLLEEEKIVSHYFPLTEVGMVETSPLPAKPFNQFEEKISTGPLGDLSRGYQETLPSYAQVGAQEVEGEGPPAEEGAEPEVGEKKEEAERLTTEEQEKVAVPEGEKVETPGVDKEGEKEEPQSEKVSKQGLPAEKTPSLCPELTTDDARPLSRLSKASSRARSDDLTV", "length": 433 }, "evidence": [ { "id": "F1NRH7", "url": "https://omabrowser.org/oma/group/F1NRH7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8K4Q9-1", "protein_name": "Gap junction alpha-8 protein", "gene_name": "Gja8", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGDWSFLGNILEEVNEHSTVIGRVWLTVLFIFRILILGTAAEFVWGDEQSDFVCNTQQPGCENVCYDEAFPISHIRLWVLQIIFVSTPSLMYVGHAVHHVRMEEKRKDREAEELCQQSRSNGGERVPIAPDQASIRKSSSSSKGTKKFRLEGTLLRTYVCHIIFKTLFEVGFIVGHYFLYGFRILPLYRCSRWPCPNVVDCFVSRPTEKTIFILFMLSVAFVSLFLNIMEMSHLGMKGIRSAFKRPAEQPLGEIAEKSLHSIAVSSIQKAKGYQLLEEEKIVSHYFPLTEVGMVETSPLSAKPFSQFEEKIGTGPLADMSRGYQETLPSYAQVGAQEVEREEQPVEEAVEPEVGEKKQEAEKVAPEGQETVAVPDGEKVETPGVGKDDEKEELQAEKVTKQGLSAEKAPTLCPELTTDDNRPLSRLSKASSRARSDDLTI", "length": 440 }, "evidence": [ { "id": "F1NRH7", "url": "https://omabrowser.org/oma/group/F1NRH7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "cell-cell signaling", "id": "GO:0007267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007267", "evidence": [ { "database": "UniProtKB", "id": "F1NRH7", "url": "https://www.uniprot.org/uniprotkb/F1NRH7" } ], "pmid": "" }, { "name": "gap junction-mediated intercellular transport", "id": "GO:1990349", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990349", "evidence": [ { "database": "UniProtKB", "id": "F1NRH7", "url": "https://www.uniprot.org/uniprotkb/F1NRH7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "connexin complex", "id": "GO:0005922", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005922", "evidence": [ { "database": "UniProtKB", "id": "F1NRH7", "url": "https://www.uniprot.org/uniprotkb/F1NRH7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "gap junction channel activity", "id": "GO:0005243", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005243", "evidence": [ { "database": "UniProtKB", "id": "F1NRH7", "url": "https://www.uniprot.org/uniprotkb/F1NRH7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1NRH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NRH7" }, { "id": "SM00037", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00037" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Connexin N-terminal", "eco_id": "ECO_0000259", "start_pos": 43, "end_pos": 76, "start_aa": "Leu", "end_aa": "Arg", "glycosite_overlap": "" }, { "evidence": [ { "id": "F1NRH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NRH7" }, { "id": "SM01089", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM01089" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Connexin cysteine-rich", "eco_id": "ECO_0000259", "start_pos": 163, "end_pos": 229, "start_aa": "Phe", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1NRU5-1", "uniprot_ac": "F1NRU5", "uniprot_id": "F1NRU5_CHICK", "mass": { "chemical_mass": 47293.0, "monoisotopic_mass": 47293.0 }, "refseq": { "ac": "XP_414227", "name": "RNA-binding protein NOB1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_414227" }, "gene_names": [ { "name": "NOB1", "type": "recommended", "evidence": [ { "id": "F1NRU5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NRU5" } ] }, { "name": "NOB1", "type": "synonym", "evidence": [ { "id": "XP_414227", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_414227" } ] } ], "protein_names": [ { "name": "RNA-binding protein NOB1", "type": "recommended", "evidence": [ { "id": "F1NRU5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NRU5/entry#names_and_taxonomy" } ] }, { "name": "RNA-binding protein NOB1", "type": "synonym", "evidence": [ { "id": "XP_414227", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_414227" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052542.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Nov 16, 2006 this sequence version replaced XP_414227.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_414227", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_414227" } ] }, { "annotation": "May play a role in mRNA degradation. Endonuclease required for processing of 20S pre-rRNA precursor and biogenesis of 40S ribosomal subunits.", "evidence": [ { "database": "UniProtKB", "id": "F1NRU5", "url": "https://www.uniprot.org/uniprotkb/F1NRU5#function" }, { "database": "UniProtKB", "id": "ARBA00045628", "url": "https://www.uniprot.org/uniprotkb/ARBA00045628#function" }, { "database": "UniProtKB", "id": "A0A8V0Y5Q3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5Q3#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NRU5", "url": "https://www.uniprot.org/uniprotkb/F1NRU5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "NOB1", "url": "https://www.uniprot.org/uniprotkb/F1NRU5", "locus": { "chromosome": "11", "start_pos": 18686742, "end_pos": 18689319, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010008294", "url": "https://www.ensembl.org/id/ENSGALG00010008294" } ] } } ], "crossref": [ { "id": "F1NRU5", "url": "https://alphafold.ebi.ac.uk/entry/F1NRU5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000000693", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000000693", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd09876", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09876", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "415867", "url": "https://www.ncbi.nlm.nih.gov/gene/415867", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR014881", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014881", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017117", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017117", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033411", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033411", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033461", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033461", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036283", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036283", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039907", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039907", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:415867", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:415867", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "GYELECE", "url": "https://omabrowser.org/oma/group/GYELECE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y5Q3", "url": "https://www.orthodb.org/?gene=A0A8V0Y5Q3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NRU5", "url": "https://www.orthodb.org/?gene=F1NRU5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12814", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12814", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12814:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12814:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF08772", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08772", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF15017", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15017", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17146", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17146", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_414227", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_414227", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Y5Q3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5Q3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y5Q3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5Q3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NRU5", "url": "https://www.uniprot.org/uniprotkb/F1NRU5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NRU5-1", "url": "https://www.uniprot.org/uniprotkb/F1NRU5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MARVPHVVADAGAFLSGAALQDVAQSVYTVPEVLAEIRDRRARRRLAALPYELQLRRPRADFVRTVTEFAKRTGDFPSLSAADLQVLALTCQLQAETAGPGSVRLQPPDKVRLSSSPRHPEATLHLAGFHLPAKHKRPRKGRQQHGPDSSTELPDNAEFGSFLYWRPPLPSIEDELQEMLKTHSISSSPAATDELQNSEDGDGAEEEEDDEEESDDDNEGWITPSNLKQVQQDTGHCDTVPANVQVGCVTTDFSMQNVLLQMGLHVLAVNGMLIRQARSHILRCHGCFRTTSDMTKVFCPHCGNKTLKKVAVSVSEDGSLHMHFSRNPKVLNPRGLRYPLPAPQGGKHANNPHLVEDQPFPQQRLSRKARQKTNVFDPDYVAGVSPFAENDIYSRAANLQIRDRALGAGRRRLNPNAVTKKFVKRR", "length": 426, "header": "tr|F1NRU5-1|F1NRU5_CHICK Isoform 1 of RNA-binding protein NOB1 OS=Gallus gallus OX=9031 GN=NOB1 PE=1 SV=2 CANONICAL=F1NRU5-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Y5Q3-1", "url": "https://www.uniprot.org/uniprotkb/F1NRU5/entry#A0A8V0Y5Q3-1", "sequence": { "sequence": "MARVPHVVADAGAFLSGAALQDVAQSVYTVPEVLAEIRDRRARRRLAALPYELQLRRPRADFVRTVTEFAKRTGDFPSLSAADLQVLALTCQLQAETAGPGSVRLQPPDKHKRPRKGRQQHGPDSSTELPDNAEFGSFLYWRPPLPSIEDELQEMLKTHSISSSPAATDELQNSEDGDGAEEEEDDEEESDDDNEGWITPSNLKQVQQDTGHCDTVPANVQVGCVTTDFSMQNVLLQMGLHVLAVNGMLIRQARSHILRCHGCFRTTSDMTKVFCPHCGNKTLKKVAVSVSEDGSLHMHFSRNPKVLNPRGLRYPLPAPQGGKHANNPHLVEDQPFPQQRLSRKARQKTNVFDPDYVAGVSPFAENDIYSRAANLQIRDRALGAGRRRLNPNAVTKKFVKRR", "length": 402, "header": "tr|A0A8V0Y5Q3-1|A0A8V0Y5Q3_CHICK Computationally mapped isoform of RNA-binding protein NOB1 OS=Gallus gallus OX=9031 GN=NOB1 PE=3 SV=1 CANONICAL=F1NRU5-1" }, "locus": { "chromosome": "11", "start_pos": 18689261, "end_pos": 18687073, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010019831.1", "url": "https://www.ensembl.org/id/ENSGALT00010019831.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010011379.1", "url": "https://www.ensembl.org/id/ENSGALP00010011379.1" } ] } }, { "isoform_ac": "F1NRU5-1", "url": "https://www.uniprot.org/uniprotkb/F1NRU5/entry#F1NRU5-1", "sequence": { "sequence": "MARVPHVVADAGAFLSGAALQDVAQSVYTVPEVLAEIRDRRARRRLAALPYELQLRRPRADFVRTVTEFAKRTGDFPSLSAADLQVLALTCQLQAETAGPGSVRLQPPDKVRLSSSPRHPEATLHLAGFHLPAKHKRPRKGRQQHGPDSSTELPDNAEFGSFLYWRPPLPSIEDELQEMLKTHSISSSPAATDELQNSEDGDGAEEEEDDEEESDDDNEGWITPSNLKQVQQDTGHCDTVPANVQVGCVTTDFSMQNVLLQMGLHVLAVNGMLIRQARSHILRCHGCFRTTSDMTKVFCPHCGNKTLKKVAVSVSEDGSLHMHFSRNPKVLNPRGLRYPLPAPQGGKHANNPHLVEDQPFPQQRLSRKARQKTNVFDPDYVAGVSPFAENDIYSRAANLQIRDRALGAGRRRLNPNAVTKKFVKRR", "length": 426, "header": "tr|F1NRU5-1|F1NRU5_CHICK Isoform 1 of RNA-binding protein NOB1 OS=Gallus gallus OX=9031 GN=NOB1 PE=1 SV=2 CANONICAL=F1NRU5-1" }, "locus": { "chromosome": "11", "start_pos": 18689261, "end_pos": 18687073, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010019835.1", "url": "https://www.ensembl.org/id/ENSGALT00010019835.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010011383.1", "url": "https://www.ensembl.org/id/ENSGALP00010011383.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:415867", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:415867", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "F1MDA9-1", "protein_name": "RNA-binding protein NOB1", "gene_name": "NOB1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAPVEHVVADAGAFLLDAALQDIGKNIYTIRNVISEIRDKATRRRLAVLPYELRFKEPFPEYVRLVTEFSKKTGDYPSLSATDIQVLALTYQLEAEFVGVSHLKQEPEKVKVSSSIQHPETPLHVSGFHLPSKPKPPRETVEHRHPASEPEDLEFSSFMFWRNPLPNIDCELQELLMDGGEDVPNEEEDEENGLDERQDQDSDDDGGGWITPSNIKQIQQEMKQCAVPKDVRVGCVTTDFAMQNVLLQMGLHVLAVNGMLIREARSYILRCHGCFKTTSDMSRVFCAHCGNKTLKKVSVTVSDDGTLHMHFSRNPKVLNPRGLRYSLPTPKGGKYAINPHLTEDQRFPQLRLSRKARQKTDVFAPDYVAGVSPFAENDISSRSATLQVRDSTLGAGRRRLNPNASRKKFVKKR", "length": 413 }, "evidence": [ { "id": "F1NRU5", "url": "https://omabrowser.org/oma/group/F1NRU5/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1S396-1", "protein_name": "RNA-binding protein NOB1", "gene_name": "NOB1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAPVEHVVADAGAFLQNAALQDIGKNIYTIRDVVSEIRDKATRRRLAVLPYELRFKEPFPEYVRLVTEFSKKTGDYPSLSATDIQVLALTYQLEAEFVGVSHLKQEPEKVKVSSSSQHPETPLHISGFHLPSKPKRPQETVEHGEPARASEDLEFTSFVFWRNPLPDIDRDLQELLIDGGGCVPSEEEKEEDGLEEGKDQDSDDDGGGWITPSNIKQIQQELERCSVPKDVRVGCVTTDFAMQNVLLQMGLHVLAVNGMLIREARSYILRCHGCFKTTSDMSRVFCSHCGNKTLKKVSVTVSDDGTLHMHFSRNPKVLNPRGLRYSLPAPKGGKYAINPHLTEDQRFPQLRLSRKARQKTDVFAPDYVAGVSPFAENDISSRSATLQVRDSTLGAGRRRLNPNASRKKFVKKR", "length": 413 }, "evidence": [ { "id": "F1NRU5", "url": "https://omabrowser.org/oma/group/F1NRU5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "I3ISV3-1", "protein_name": "RNA-binding protein NOB1", "gene_name": "nob1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MVATIVEHVVVDAGAFIKRAPLHEIGKNIYTLKDVVDEIRDKPTKRSLAFLPYKLDFKEPFPEYIQFVTEFAKKTGDYPSLSATDIKVLALTYQLESENVGTEHLKKEPEKQVQICSTQRHPETPVGIAGFHFPSKSSGKSAIQSPPTTNEPHDPVSSQFNTFQFWRNPLPSIESELLELLAADAITVTQKLESVNLSAESEEHEGNNGEQHEEEEEEEFNSDDEEEEEDDEDGGGWITPSNIKQVQMDAGVRGPSADVKVGCVTTDFAMQNVLIQIGLNVLSVNGMLIKNTRSYILRCHACFKTTTNMNKSFCPNCGNNTLKKIAVTLNEDGTMQMHFSRNPKVLNPKGKRYSLPMPQGGKHGNNPHLVEDQRFPQQRMSRKARQKTNVFDPDYLASSSPFSEHDVYSKSASLQLRDGQTGGGRRRTNPNAARKKFVKK", "length": 440 }, "evidence": [ { "id": "F1NRU5", "url": "https://omabrowser.org/oma/group/F1NRU5/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q08444-1", "protein_name": "20S-pre-rRNA D-site endonuclease NOB1", "gene_name": "NOB1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MTENQTAHVRALILDATPLITQSYTHYQNYAQSFYTTPTVFQEIKDAQARKNLEIWQSLGTLKLVHPSENSIAKVSTFAKLTGDYSVLSANDLHILALTYELEIKLNNGDWRLRKKPGDALDASKADVGTDGKQKLTEDNKKEEDSESVPKKKNKRRGGKKQKAKREAREAREAENANLELESKAEEHVEEAGSKEQICNDENIKESSDLNEVFEDADDDGDWITPENLTEAIIKDSGEDTTGSLGVEASEEDRHVALNRPENQVALATGDFAVQNVALQMNLNLMNFMSGLKIKRIRNYMLRCHACFKIFPLPKDGKPKHFCASCGGQGTLLRCAVSVDSRTGNVTPHLKSNFQWNNRGNRYSVASPLSKNSQKRYGKKGHVHSKPQENVILREDQKEYEKVIKQEEWTRRHNEKILNNWIGGGSADNYISPFAITGLKQHNVRIGKGRYVNSSKRRS", "length": 459 }, "evidence": [ { "id": "F1NRU5", "url": "https://omabrowser.org/oma/group/F1NRU5/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q54W91-1", "protein_name": "RNA-binding protein NOB1", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSEPIENNIVDKQQEEEEEVEYEELTEEQLKELNELNENSNDNPFGERSVTAESDELVKSMETLAMTNEKTTASYLIIDTNALISGTRLETLGKELWTIPEVLEEVKDKKTSTFLTSFPFEIKTRQPTHESMVAVSEFSKKTGDYPSLSATDMKLIALTYTFEAQVNGIDHIKTEPEKLQVVTKKPVHKKNNNNNNNNNNNNKKDNKSESASESNTTTESTTTTTTTTSTATTTTTADKPKKKKNKNKNKKSKPISTDNKNIESTTTDSCCDHKHEEKEEEKVEKVEQVEKVEKVEKVEEEKESVNNNNNNTNNNNDNNNNNITGKKKRNNKLMVNLEKIEEEVSKENLVDPKEVLRQLKIKQAEEAEERKKNRVIKVEDEGEWITPDNIKNKLSSTYVQEKVHYDVGCITRDFSMQNVILQMGLHLISADGVVIKQVKQFVLKCVACLNITTDMDKIFCGHCGNKSLYKATTYVDRNGNQRVSVGSAKQFNLRGTIYSIPKPKGGKKSNDIILTEDQYLHKLRVTGQLYKKKVSKEINMNDLDLGFGHKGPSDDIVIGYGNKNPNVARKRIGKKNKSISIF", "length": 582 }, "evidence": [ { "id": "F1NRU5", "url": "https://omabrowser.org/oma/group/F1NRU5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q6VEU1-1", "protein_name": "RNA-binding protein NOB1", "gene_name": "Nob1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAPVEHVVADAGAFLRDAPLQDIGKNIYTIREVVREIRDKATRRRLAVLPYELRFKEPFPEYVRLVTEFSKKTGDYPSLSATDIQVLALTYQLEAEFVGVSHLKKEPEKVKVSSSIQHPETPLHISGFHLPSKSKALQETVDHGPPADGSENLEFSSFMFWRNPLPNIDHELQQLLIDGREEEEEEEEEEEEEDELEDSDDDGGGWITPSNIKQIQHESEQCDIPKDVQVGCVTTDFAMQNVLLQMGLHVLAVNGMLVREARSYILRCHGCFKTTSDMNRVFCGHCGNKTLKKVSVTINDDGTLHMHFSRNPKVLNPRGLRYSLPTPKGGKYAVNPHLTEDQRFPQLRLSHKARQKTNVFAPDYIAGVSPFAENDISSRSAILQVRDSMLGAGRRRLNPNASRKKFVKKR", "length": 410 }, "evidence": [ { "id": "F1NRU5", "url": "https://omabrowser.org/oma/group/F1NRU5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8BW10-1", "protein_name": "RNA-binding protein NOB1", "gene_name": "Nob1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAPVEHVVADAGAFLRDAPLQDIGKNIYTIREVVREIRDKATRRRLAVLPYQLRFKEPLPEYVRLVTEFSKKTGDYPSLSATDIQVLALTYQLEAEFVGVSHLKKEPEKAKVSSSIQHPETALHISGFHLPSKSKPLQEAVDRGHAADGPENLEFSSFMFWRTPLPNIDRELQELLIDGREEEEEEEECEDSDDDGGGWITPSNIKQIQQELEQCDTPEDVQVGCVTTDFAMQNVLLQMGLHVLAVNGMLVREARSYILRCHGCFKTTSDMNRVFCGHCGNKTLKKVSVTINDDGTLHMHFSRNPKVLNPRGLRYSLPTPKGGKYAINPHLTEDQRFPQLRLSQKARQKTDVFAPDYIAGVSPFAENDISSRSAILQVRDGMLGAGRRRLNPNASRKKFVKKR", "length": 403 }, "evidence": [ { "id": "F1NRU5", "url": "https://omabrowser.org/oma/group/F1NRU5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9FLL1-1", "protein_name": "RNA-binding NOB1-like protein", "gene_name": "NOB1", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MDPKPTSMWSSIVKKDPPSKPPVNDGAPAAILGMVGNCKSTKGISIAVVDANAIIEGRQSLTNFADKFVTVPEVLSEIRDPASRRRLAFIPFTIDTMEPSPESLSKVIKFARATGDLQSLSDVDLKLIALSYTLEAQVYGTKNLRDVPPPIQTVRVKRLPEKDLPGWGSNVANLEEWEALENETEEKSNANSKILPLKDLNMNIIASDNVSEVGSVVSHTENHEEDVQEGGKKHRRYPPKKTEIKLEGKMVVEGVDASQGQYDDDDDASDWRPAVSRSTHSKYLRRKARWEHYNALAEQEIQKDQEADKARHTKEANETHAKDSGKNGEDISSILKDMRLEEESLRALQEETEETNAEATLINGEDDIDHDIEVEAEGIDVANQALENLEIASEAEDTFEASSIGDDGSSEQSWSLRALSESSVACITGDYAMQNVILQMGLRLLAPGGMQIRQLHRWILKCHACYTVTPEIGRIFCPKCGNGGTLRKVAVTIGANGAIIAACKPRITLRGTQYSIPMPKGGREAITKNLILREDQLPQKLLHPRTKKKASKPGDEYFVSDDVFLNHHSDRKAPLQPPVRKAMSVFSQKRNPNDNHYSRSMH", "length": 602 }, "evidence": [ { "id": "F1NRU5", "url": "https://omabrowser.org/oma/group/F1NRU5/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9ULX3-1", "protein_name": "RNA-binding protein NOB1", "gene_name": "NOB1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAPVEHVVADAGAFLRHAALQDIGKNIYTIREVVTEIRDKATRRRLAVLPYELRFKEPLPEYVRLVTEFSKKTGDYPSLSATDIQVLALTYQLEAEFVGVSHLKQEPQKVKVSSSIQHPETPLHISGFHLPYKPKPPQETEKGHSACEPENLEFSSFMFWRNPLPNIDHELQELLIDRGEDVPSEEEEEEENGFEDRKDDSDDDGGGWITPSNIKQIQQELEQCDVPEDVRVGCLTTDFAMQNVLLQMGLHVLAVNGMLIREARSYILRCHGCFKTTSDMSRVFCSHCGNKTLKKVSVTVSDDGTLHMHFSRNPKVLNPRGLRYSLPTPKGGKYAINPHLTEDQRFPQLRLSQKARQKTNVFAPDYIAGVSPFVENDISSRSATLQVRDSTLGAGRRRLNPNASRKKFVKKR", "length": 412 }, "evidence": [ { "id": "F1NRU5", "url": "https://omabrowser.org/oma/group/F1NRU5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9W2Y4-1", "protein_name": "RNA-binding protein NOB1", "gene_name": "Dmel\\CG2972", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MAETSEKIKFLVADTTAFINAVPLNEYAEQVLTVPDVVAEVRNKRQIRRLCVLPFDLQVREPRPESIKHCVEFAKKTGDYASLSGIDLKVISLTYELEADNVGTDHLRQEPVMAQTIASKDKPEEMQDANNKRLVGWYMPEGEEEEEEDSEEEDDYSQEEDDAEGDEQEANESPDTVKAAIEAQLAGKEPFASETIEKEEDQDQEPSQEELDKLFEQLKCAPSAEEEKELSELLVSQPAEVDEEVSEPQEAKQSQNLDEDVGDDGWITHSNIKKAKKALEGKVETDEVPPVACMTTDYALQNVLKQLNLHLAALNGRIIKQLRTYILRCYACYKTTSIMTKVFCPNCGNKTLKRVAVSLDENGRQVIHINTRRPLTNKYKNQSLPRFQGGKHSRNPILFEDQPMPRQMPSRVAKTKTNALDQDYTAGFSPFVLRDVDSKSAMLRSKGNLKEWARNNNFEEDRRRKNYNRLYK", "length": 472 }, "evidence": [ { "id": "F1NRU5", "url": "https://omabrowser.org/oma/group/F1NRU5/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1NRU5", "url": "https://www.uniprot.org/uniprotkb/F1NRU5" } ], "pmid": "" }, { "name": "preribosome, small subunit precursor", "id": "GO:0030688", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030688", "evidence": [ { "database": "UniProtKB", "id": "F1NRU5", "url": "https://www.uniprot.org/uniprotkb/F1NRU5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "F1NRU5", "url": "https://www.uniprot.org/uniprotkb/F1NRU5" } ], "pmid": "" }, { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "F1NRU5", "url": "https://www.uniprot.org/uniprotkb/F1NRU5" } ], "pmid": "" }, { "name": "RNA endonuclease activity", "id": "GO:0004521", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004521", "evidence": [ { "database": "UniProtKB", "id": "F1NRU5", "url": "https://www.uniprot.org/uniprotkb/F1NRU5" } ], "pmid": "" } ] }, 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The reference sequence was derived from JAENSK010000356.1. On Jan 28, 2010 this sequence version replaced XP_417947.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001165357", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001165357" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NRX4", "url": "https://www.uniprot.org/uniprotkb/F1NRX4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LAMTOR5", "url": "https://www.uniprot.org/uniprotkb/F1NRX4", "locus": { "chromosome": "26", "start_pos": 1460299, "end_pos": 1462600, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010027339", "url": "https://www.ensembl.org/id/ENSGALG00010027339" } ] } } ], "crossref": [ { "id": "F1NRX4", "url": "https://alphafold.ebi.ac.uk/entry/F1NRX4", "database": "AlphaFoldDB", "categories": [] }, { "id": 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"url": "https://www.uniprot.org/uniprotkb/F1NRX4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEGTLEQHLEDTMKSPAVVGVLCTDSQGLNLGCRGTLSDEHAGVISVLAQQAAKLTSDPTDTPVVCLESDSGNIMIQKHDSITVAVHKLAS", "length": 91, "header": "tr|F1NRX4-1|F1NRX4_CHICK Isoform 1 of Ragulator complex protein LAMTOR5 OS=Gallus gallus OX=9031 GN=LAMTOR5 PE=1 SV=2 CANONICAL=F1NRX4-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A8Q0-1", "url": "https://www.uniprot.org/uniprotkb/F1NRX4/entry#A0A8V1A8Q0-1", "sequence": { "sequence": "MEGTLEQHLEDTMKSPAVVGVLCTDSQGLNLGCRGTLSDEHAGVISVLAQQAAKLTSDPTDTPVVCLESDSGSPIAEAALEGWTPMGVWKAVRFTGPRVLGTAEAAGSLSGVGGCCSTVFLLLLGSPWII", "length": 130, "header": "tr|A0A8V1A8Q0-1|A0A8V1A8Q0_CHICK Computationally mapped isoform of Ragulator complex protein LAMTOR5 OS=Gallus gallus OX=9031 GN=LAMTOR5 PE=1 SV=1 CANONICAL=F1NRX4-1" }, "locus": { "chromosome": "26", "start_pos": 1462518, "end_pos": 1460847, "strand": "+", "evidence": [ { "database": "Ensembl 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} }, { "isoform_ac": "A0A8V1ABE2-1", "url": "https://www.uniprot.org/uniprotkb/F1NRX4/entry#A0A8V1ABE2-1", "sequence": { "sequence": "MEGTLEQHLEDTMKSPAVVGVLCTDSQGLNLGCRGTLSDEHAGVISVLAQQAAKLTSDPTDTPVVCLESDSGSPIAEAALEGWTPMGEHHDPEA", "length": 94, "header": "tr|A0A8V1ABE2-1|A0A8V1ABE2_CHICK Computationally mapped isoform of Ragulator complex protein LAMTOR5 OS=Gallus gallus OX=9031 GN=LAMTOR5 PE=1 SV=1 CANONICAL=F1NRX4-1" }, "locus": { "chromosome": "26", "start_pos": 1462518, "end_pos": 1460642, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066288.1", "url": "https://www.ensembl.org/id/ENSGALT00010066288.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040554.1", "url": "https://www.ensembl.org/id/ENSGALP00010040554.1" } ] } }, { "isoform_ac": "F1NRX4-1", "url": "https://www.uniprot.org/uniprotkb/F1NRX4/entry#F1NRX4-1", "sequence": { "sequence": "MEGTLEQHLEDTMKSPAVVGVLCTDSQGLNLGCRGTLSDEHAGVISVLAQQAAKLTSDPTDTPVVCLESDSGNIMIQKHDSITVAVHKLAS", "length": 91, "header": "tr|F1NRX4-1|F1NRX4_CHICK Isoform 1 of Ragulator complex protein LAMTOR5 OS=Gallus gallus OX=9031 GN=LAMTOR5 PE=1 SV=2 CANONICAL=F1NRX4-1" }, "locus": { "chromosome": "26", "start_pos": 1462518, "end_pos": 1460605, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066292.1", "url": "https://www.ensembl.org/id/ENSGALT00010066292.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040558.1", "url": "https://www.ensembl.org/id/ENSGALP00010040558.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:419811", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419811", "resource": "KEGG Pathway" }, { "id": "R-GGA-1632852", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1632852", "resource": "Reactome", "description": "Macroautophagy" }, { "id": "R-GGA-165159", "name": "", "url": 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"Q3SZ68-1", "protein_name": "Ragulator complex protein LAMTOR5", "gene_name": "LAMTOR5", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MEATLEQHLEDTMKNPSIVGVLCTDSQGLNLGCRGTLSDEHAGVISVLAQQAAKLTSDPTDIPVVCLESDNGNIMIQKHDGITVAVHKMAS", "length": 91 }, "evidence": [ { "id": "F1NRX4", "url": "https://omabrowser.org/oma/group/F1NRX4/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q66X52-1", "protein_name": "Ragulator complex protein LAMTOR5", "gene_name": "LAMTOR5", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEATLEQHLEDTMKNPSIVGVLCTDSQGLNLGCRGTLSDEHAGVISVLAQQAAKLTSDPTDIPVVCLESDNGNIMIQKHDGITVAVHKMAS", "length": 91 }, "evidence": [ { "id": "F1NRX4", "url": "https://omabrowser.org/oma/group/F1NRX4/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q9D1L9-1", "protein_name": "Ragulator complex protein LAMTOR5", "gene_name": "Lamtor5", "tax_id": 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], "pmid": "" }, { "name": "guanyl-nucleotide exchange factor activity", "id": "GO:0005085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005085", "evidence": [ { "database": "UniProtKB", "id": "F1NRX4", "url": "https://www.uniprot.org/uniprotkb/F1NRX4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", 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"uniprot_ac": "F1NRZ6", "uniprot_id": "F1NRZ6_CHICK", "mass": { "chemical_mass": 115648.0, "monoisotopic_mass": 115648.0 }, "refseq": { "ac": "XP_015154207", "name": "importin-9", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015154207" }, "gene_names": [ { "name": "IPO9", "type": "recommended", "evidence": [ { "id": "F1NRZ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NRZ6" } ] }, { "name": "IPO9", "type": "synonym", "evidence": [ { "id": "XP_015154207", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015154207" } ] } ], "protein_names": [ { "name": "Importin 9", "type": "synonym", "evidence": [ { "id": "F1NRZ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NRZ6/entry#names_and_taxonomy" } ] }, { "name": "importin-9", "type": "synonym", "evidence": [ { "id": "XP_015154207", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015154207" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052557.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On May 17, 2018 this sequence version replaced XP_015154207.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015154207", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015154207" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NRZ6", "url": "https://www.uniprot.org/uniprotkb/F1NRZ6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "IPO9", "url": "https://www.uniprot.org/uniprotkb/F1NRZ6", "locus": { "chromosome": "26", "start_pos": 630823, "end_pos": 610916, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010026102", "url": "https://www.ensembl.org/id/ENSGALG00010026102" } ] } } ], "crossref": [ { "id": "F1NRZ6", "url": "https://alphafold.ebi.ac.uk/entry/F1NRZ6", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000000397", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000000397", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "421167", "url": "https://www.ncbi.nlm.nih.gov/gene/421167", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001494", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001494", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056840", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056840", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR058669", "url": "https://www.ebi.ac.uk/interpro/entry/IPR058669", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:421167", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:421167", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "NPDQYTI", "url": "https://omabrowser.org/oma/group/NPDQYTI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1NRZ6", "url": "https://www.orthodb.org/?gene=F1NRZ6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10997", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10997", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10997:SF9", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10997:SF9", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03810", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03810", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25018", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25018", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25758", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25758", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015154207", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015154207", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1NRZ6", "url": "https://www.uniprot.org/uniprotkb/F1NRZ6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NRZ6-1", "url": "https://www.uniprot.org/uniprotkb/F1NRZ6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAGAAAAGGPGGGGPGPVAQGLKEALVETLTGILCPVQAVRAAAEEQVKVLEVTEEFGVHLAELTVDPQGALAIRQLASVILKQYVETHWCSQSEKFRPPETTERAKVAIRELLPNGLRESISKVRSSVAYAVSAIAHWDWPEAWPELFNLLMEMLVSGDVNVVHGAMRVLTEFTREVTDTQMPHVAPVILPEMYKIFTMAEVYGIRTRSRAVEIFTTCAHMICNMEELEKGAAKVLIFPVVQQFTEAFVQALQMPDGPTSDSGFKMEVLKAVTALVKNYPKHMVSSMQQILPIVWNTLTESAAFYVRTEVNYTEEVEDPVDSDGEVLGFENLVFSIFEFVHALLENNKFKSTVKKALPELIYYILLYMQITEEQIKVWTANPQQFVEDEDDDTFSYTVRIAAQDLLLAVAADFQNESASALAAAATRHLQEAEQAKNSGAEHWWKIHEACMLALGSVKSIITDSVKNGRIHFDMHGFLTNVVLADLNLSVSPFLLGRALWAASRFTVAMSPELIQQFLQATVSGLHETQPPSVRISAVRAIWGYCDQLKISESTHVLQPFLPSILDGLIHLATQFSSEVLNLVMETLCIVCTVDPAFTASVENKICPFTIAIFLKYSNDPVVASLAQDIFKELAQIEACQGPMQMRLIPTLVSIMQAPADKIPAGLCATSIDILTTVVRNTKPPLSQLLICQAFPAVAQCSLNTDDNATMQNGGECLRAYVSVALEQIAQWHDEQGHNGLWYVMQVVSQLLDPRTSEFTAAFVGRLVSTLISKAGSELGENLDQILRAILSKMQQAETLSVMQSLIMVFAHLVHSQLEPLLEFLCSLPGPTGKPALEFVMAEWMSRQHLFYGQYEGKVSSVALCKLLQYGINTDDKRLQDIRVKGEEIFNMDEGIRTRSKSAKNPERWTNIPLLVKILKLIINELSNAMEANASRQTTTDWSQDDSNDMWEDQEEDEDEDEGLAGQFLSDILSTNKYDEDYYEDDEEDDPDALKDPLYQIDLQAYLTDFLCQFAQQPCYAMFSDHLNENEKRVLQAIGI", "length": 1040, "header": "tr|F1NRZ6-1|F1NRZ6_CHICK Isoform 1 of Importin 9 OS=Gallus gallus OX=9031 GN=IPO9 PE=1 SV=3 CANONICAL=F1NRZ6-1" }, "isoforms": [ { "isoform_ac": "F1NRZ6-1", "url": "https://www.uniprot.org/uniprotkb/F1NRZ6/entry#F1NRZ6-1", "sequence": { "sequence": "MAGAAAAGGPGGGGPGPVAQGLKEALVETLTGILCPVQAVRAAAEEQVKVLEVTEEFGVHLAELTVDPQGALAIRQLASVILKQYVETHWCSQSEKFRPPETTERAKVAIRELLPNGLRESISKVRSSVAYAVSAIAHWDWPEAWPELFNLLMEMLVSGDVNVVHGAMRVLTEFTREVTDTQMPHVAPVILPEMYKIFTMAEVYGIRTRSRAVEIFTTCAHMICNMEELEKGAAKVLIFPVVQQFTEAFVQALQMPDGPTSDSGFKMEVLKAVTALVKNYPKHMVSSMQQILPIVWNTLTESAAFYVRTEVNYTEEVEDPVDSDGEVLGFENLVFSIFEFVHALLENNKFKSTVKKALPELIYYILLYMQITEEQIKVWTANPQQFVEDEDDDTFSYTVRIAAQDLLLAVAADFQNESASALAAAATRHLQEAEQAKNSGAEHWWKIHEACMLALGSVKSIITDSVKNGRIHFDMHGFLTNVVLADLNLSVSPFLLGRALWAASRFTVAMSPELIQQFLQATVSGLHETQPPSVRISAVRAIWGYCDQLKISESTHVLQPFLPSILDGLIHLATQFSSEVLNLVMETLCIVCTVDPAFTASVENKICPFTIAIFLKYSNDPVVASLAQDIFKELAQIEACQGPMQMRLIPTLVSIMQAPADKIPAGLCATSIDILTTVVRNTKPPLSQLLICQAFPAVAQCSLNTDDNATMQNGGECLRAYVSVALEQIAQWHDEQGHNGLWYVMQVVSQLLDPRTSEFTAAFVGRLVSTLISKAGSELGENLDQILRAILSKMQQAETLSVMQSLIMVFAHLVHSQLEPLLEFLCSLPGPTGKPALEFVMAEWMSRQHLFYGQYEGKVSSVALCKLLQYGINTDDKRLQDIRVKGEEIFNMDEGIRTRSKSAKNPERWTNIPLLVKILKLIINELSNAMEANASRQTTTDWSQDDSNDMWEDQEEDEDEDEGLAGQFLSDILSTNKYDEDYYEDDEEDDPDALKDPLYQIDLQAYLTDFLCQFAQQPCYAMFSDHLNENEKRVLQAIGI", "length": 1040, "header": "tr|F1NRZ6-1|F1NRZ6_CHICK Isoform 1 of Importin 9 OS=Gallus gallus OX=9031 GN=IPO9 PE=1 SV=3 CANONICAL=F1NRZ6-1" }, "locus": { "chromosome": "26", "start_pos": 629844, "end_pos": 610984, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010063601.1", "url": "https://www.ensembl.org/id/ENSGALT00010063601.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039257.1", "url": "https://www.ensembl.org/id/ENSGALP00010039257.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 260, "start_aa": "Thr", "end_pos": 260, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr260", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:421167", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:421167", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D4A857-1", "protein_name": "Importin 9", "gene_name": "Ipo9", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAAAAAAGAASGLPGPVAQGLKEALVDTLTGILSPVQEVRAAAEEQIKVLEVTEEFGVHLAELTVDPQGALAIRQLASVILKQYVETHWCAQSEKFRPPETTERAKIVIRELLPNGLRESISKVRSSVAYAVSAIAHWDWPEAWPQLFNLLMEMLVSGDLNAVHGAMRVLTEFTREVTDTQMPLVAPVILPEMYKIFTMAEVYGIRTRSRAVEIFTTCAHMICNMEELEKGAAKVLIFPVVQQFTEAFVQALQMPDGPTSDSGFKMEVLKAVTALVKNFPKHMVSSMQQILPIVWNTLTESAAFYVRTEVNYTEEVEDPVDSDGEVLGFENLVFSIFEFVHALLENSKFKSTVKKALPELIYYIILYMQITEEQIKVWTANPQQFVEDEDDDTFSYTVRIAAQDLLLAVATDFQNESAVALATAATRHLQEAEQTKASGTEHWWKIHEACMLALGSVKSIITDSVKNGRIHFDMHGFLTNVILADLNLSASPFLLGRALWAASRFTVAMSPELIQQFLQATVSGLHETQPPSVRISAVRAIWGYCDQLKVSESTHVLQPFLPSILDGLIHLAAQFSSEVLNLVMETLCIVCTVDPEFTASVESKICPFTIAIFLKYSNDPVVASLAQDIFKELSQIEACQGPMQMRLIPTLVSIMQAPADKIPAGLCATAIDILTTVVRNTKPPLSQLLICQAFPAVAQCTLHTDDNATMQNGGECLRAYVSVTLEQVAQWHDEQGHNGLWYVMQVVSQLLDPRTSEFTAAFVGRLVSTLISKAGRELGENLDQILRAILSKMQQAETLSVMQSLIMVFAHLVHTQLEPLLEFLCSLPGPTGKPALEFVMAEWTSRQHLFYGQYEGKVSSVALCKLLQHGINADDKRLQDIRVKGEEIYSMDEGIRTRSKSAKNPERWTNIPLLVKILKLIINELSNVMEANAARQATPAEWNQDDSNDMWEDQEEEEEEEEDGLAGQLLSDILATSKYEEDYYEDDEEDDPDALKDPLYQIDLQAYLTDFLCQFAQQPCYIMFSCHLNDTERRVLQTIGI", "length": 1041 }, "evidence": [ { "id": "F1NRZ6", "url": "https://omabrowser.org/oma/group/F1NRZ6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F4IE40-1", "protein_name": "ARM repeat superfamily protein", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MVVDQDQQWLLGCLSASLDPNQNVRSFAETSLNQASLQPGFGSALCRVAANKDLSLGLRQLAAVLLKQFIKKHWRENEEAFEYPLVSSEEKALIRGQLLGSLDDSHRKICTAISMDISSIATYDWPEEWPELVPFLLKLISDPSNTNGVHGALRCLALLSGELDDKEVPTLVPVLFPCLHAVVSSPQSYDKYIRGKALTIVYSCIYVLGAMSGVYKTETTTLVTPVLKVWMNQFSLILEHPVQREDPDDWSLRMEVLKCLNQFVQNFPSLIESELMAIMRPLWHTFESSLQVYLRSSIDGAEDSYDGRYDSDGEEKSLDTFVIQLFEFLSTIVSSRRLSKTIAGNVRELVYQTVAFLQITEQQVHTWSMDVNQFVADEDEGSYSCRISGILLLEEVINTFGSEGINAVVDAAGKRFQESQRENSASSLSWWRLREAVLFTLASLSDQLVEAEDLRIDPANLAKFIEQLIMEDTGIGYHECPFLYARIFTAVAKFSSVINAGILEHFLNAAVRAITMDVPPPVKVGACRALLQLLPDMNSSVILPQIMNLFSSLTDLLRQATDETLVLVLETLQQAIKAGHEASASIESIISPVILNVWVAHISDPFMSIDVIDVLEAIKNSPGCLHPLTSRILPFIGPILNKPHQQPEGLASGSLDLLTMLLKGAPSDIVKTAYDFCFAAVIRIVLHSEDHGELQNATECLAAFISSGRQELLTWSGDPGFTMRSLLDATSRLLNPDLEGSGSLFAGKYILQLILHLPSEMAPHVQDLVAALVRRLQSAEILALKGSLLLIFARLVHMSYPNVDQFINLLVSIPADGHENSFTYVMTEWTKQQGEIQSAYQIKVTTSALALLLSTRHSEFAKVNVPGSPIQSNGGITTRSKARSAPEQWTIIPLPMKILALLADTLIEIQEQVLSNEDEDSEWEEVHEGDAKAEKDLLRSAGTSQFSKPTYDQLEAMARFENQDDEVDDHLLGTDPLNEINLASYVADFLLKFSSEDRPLFDNLCQGLTNAQRNVIHMALNR", "length": 1022 }, "evidence": [ { "id": "F1NRZ6", "url": "https://omabrowser.org/oma/group/F1NRZ6/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "P53067-1", "protein_name": "Importin subunit beta-5", "gene_name": "KAP114", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MDINELIIGAQSADKHTREVAETQLLQWCDSDASQVFKALANVALQHEASLESRQFALLSLRKLITMYWSPGFESYRSTSNVEIDVKDFIREVLLKLCLNDNENTKIKNGASYCIVQISAVDFPDQWPQLLTVIYDAISHQHSLNAMSLLNEIYDDVVSEEMFFEGGIGLATMEIVFKVLNTETSTLIAKIAALKLLKACLLQMSSHNEYDEASRKSFVSQCLATSLQILGQLLTLNFGNVDVISQLKFKSIIYENLVFIKNDFSRKHFSSELQKQFKIMAIQDLENVTHINANVETTESEPLLETVHDCSIYIVEFLTSVCTLQFSVEEMNKIITSLTILCQLSSETREIWTSDFNTFVSKETGLAASYNVRDQANEFFTSLPNPQLSLIFKVVSNDIEHSTCNYSTLESLLYLLQCILLNDDEITGENIDQSLQILIKTLENILVSQEIPELILARAILTIPRVLDKFIDALPDIKPLTSAFLAKSLNLALKSDKELIKSATLIAFTYYCYFAELDSVLGPEVCSETQEKVIRIINQVSSDAEEDTNGALMEVLSQVISYNPKEPHSRKEILQAEFHLVFTISSEDPANVQVVVQSQECLEKLLDNINMDNYKNYIELCLPSFINVLDSNNANNYRYSPLLSLVLEFITVFLKKKPNDGFLPDEINQYLFEPLAKVLAFSTEDETLQLATEAFSYLIFNTDTRAMEPRLMDIMKVLERLLSLEVSDSAAMNVGPLVVAIFTRFSKEIQPLIGRILEAVVVRLIKTQNISTEQNLLSVLCFLTCNDPKQTVDFLSSFQIDNTDALTLVMRKWIEAFEVIRGEKRIKENIVALSNLFFLNDKRLQKVVVNGNLIPYEGDLIITRSMAKKMPDRYVQVPLYTKIIKLFVSELSFQSKQPNPEQLITSDIKQEVVNANKDDDNDDWEDVDDVLDYDKLKEYIDDDVDEEADDDSDDITGLMDVKESVVQLLVRFFKEVASKDVSGFHCIYETLSDSERKVLSEALL", "length": 1004 }, "evidence": [ { "id": "F1NRZ6", "url": "https://omabrowser.org/oma/group/F1NRZ6/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q54WY2-1", "protein_name": "Importin 9", "gene_name": "cnrP", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MTITIENVIELINGLNDPKLNKHYENKLEEITNEIGFGVVLAKLASDKQFDMVHRQFSGILLKKYISKHWNEFNDSQSDEEGDDNLNEHEKIQLQQMKLQQQQQQQPKEYRVLTKEEKTEIKKLLSPCLSDPSSKIRTAIAMCIAKIGAYEWPHDWPELVDELIGCLNRVNNNDTNNNNNNDLLHGVIRCLELLCDPQDGNISEEQIEILIKQVYPVFSELLGKDIDPMIHIRIINVFRSTVTHLTYMKGVTKGLSKALFPFISTWVPIFTGHLSRVLDLGSPHINHYFTIMSAMVEIFTMLIQDFPKKTSKYIQEILPPIWTLFNNCYPIYEKVEINPVHGIVSNFVEEGITKIDRLVSSIFDFMQQIVSNQTLAPLFKPFLKPIFANSIQYMQMNYELVELWDSDPNLFLENEDDTTYTPRVVSTSLVQSMCETYKSEGSKYLFEVISETLIKAQEEKNKNSKNTNSWWKIREAALVALCDSSQQLSKIKQFDAVSFLSTNLIQDFQGTLNENDQGSLILRGRSLICASKFAKLVDPSISLPFFNQAVVLITQNIPVTLKLTAVMAIGSFAPKISAQSIVDYIPSTVQALISMINQLSEDSLLLVLDCIKMLVKIDKDITGKLEPLLIPHLSQAWINYGNDPMFSDALKEIFQIICACPKSYPGILQRMIPTLNIILSDYTNPMYNPIADSAADVLSLLIANVDQQIDSFLLDQLFSPILNILLTCDCQANRGILKASLCTLLPFVYKTSSDLLLKWTFTSASNTQSATPPTPTPTTTTINGLHGLFLVLRRVLFETDELVHVEVPSIISALLVKHSEIIGAQTVPLFESTLQAFYNCKLPSTKRAFSSVFARLIIQHKTTIIDYLAAIPGPNGNGSALVFVLNEWQKYHLEMTSKLENNVSVVAMCTLVSLNDPRLESINIDGRQIIPDRSTRDIRRKKSQYNGGLNEEWTKVNLFNKIMENLLETVKLEKEELAKNSNGTANSTPQDHHDSDEDYDDDEDEDDEDDEETTSKRYPNVDENGFAPAEEYAHMIDYAGDDDNDDLAQYLQDEFTEDAFEIISKSDPIYHIELLKYLSDFFTNLSKNSPSIFTIVAPLLNEFKLQSFGN", "length": 1110 }, "evidence": [ { "id": "F1NRZ6", "url": "https://omabrowser.org/oma/group/F1NRZ6/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q91YE6-1", "protein_name": "Importin-9", "gene_name": "Ipo9", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAAAAAGAASGLPGPVAQGLKEALVDTLTGILSPVQEVRAAAEEQIKVLEVTEEFGVHLAELTVDPQGALAIRQLASVILKQYVETHWCAQSEKFRPPETTERAKIVIRELLPNGLRESISKVRSSVAYAVSAIAHWDWPEAWPQLFNLLMEMLVSGDLNAVHGAMRVLTEFTREVTDTQMPLVAPVILPEMYKIFTMAEVYGIRTRSRAVEIFTTCAHMICNMEELEKGAAKVLIFPVVQQFTEAFVQALQMPDGPTSDSGFKMEVLKAVTALVKNFPKHMVSSMQQILPIVWNTLTESAAFYVRTEVNYTEEVEDPVDSDGEVLGFENLVFSIFEFVHALLENSKFKSTVKKALPELIYYIILYMQITEEQIKVWTANPQQFVEDEDDDTFSYTVRIAAQDLLLAVATDFQNESAVALATAATRHLQEAEQTKASGTEHWWKIHEACMLALGSVKSIITDSVKNGRIHFDMHGFLTNVILADLNLSASPFLLGRALWAASRFTVAMSPELIQQFLQATVSGLHETQPPSVRISAVRAIWGYCDQLKVSESTHVLQPFLPSILDGLIHLAAQFSSEVLNLVMETLCIVCTVDPEFTASVENKICPFTIAIFLKYSNDPVVASLAQDIFKELSQIEACQGPMQMRLIPTLVSIMQAPADKIPAGLCATAIDILTTVVRNTKPPLSQLLICQAFPAVAQCTLHTDDNATMQNGGECLRAYVSVTLEQVAQWHDEQGHNGLWYVMQVVSQLLDPRTSEFTAAFVGRLVSTLISKAGRELGENLDQILRAILSKMQQAETLSVMQSLIMVFAHLVHTQLEPLLEFLCSLPGPTGKPALEFVMAEWTSRQHLFYGQYEGKVSSVALCKLLQHGINADDKRLQDIRVKGEEIYSMDEGIRTRSKSAKNPERWTNIPLLVKILKLIINELSNVMEANAARQATPAEWNQDDSNDMWEDQEEEEEEEEDGLAGQLLSDILATSKYEEDYYEDDEEDDPDALKDPLYQIDLQAYLTDFLCQFAQQPCYIMFSCHLNDNERRVLQTIGI", "length": 1041 }, "evidence": [ { "id": "F1NRZ6", "url": "https://omabrowser.org/oma/group/F1NRZ6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96P70-1", "protein_name": "Importin-9", "gene_name": "IPO9", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAAAAAGAASGLPGPVAQGLKEALVDTLTGILSPVQEVRAAAEEQIKVLEVTEEFGVHLAELTVDPQGALAIRQLASVILKQYVETHWCAQSEKFRPPETTERAKIVIRELLPNGLRESISKVRSSVAYAVSAIAHWDWPEAWPQLFNLLMEMLVSGDLNAVHGAMRVLTEFTREVTDTQMPLVAPVILPEMYKIFTMAEVYGIRTRSRAVEIFTTCAHMICNMEELEKGAAKVLIFPVVQQFTEAFVQALQIPDGPTSDSGFKMEVLKAVTALVKNFPKHMVSSMQQILPIVWNTLTESAAFYVRTEVNYTEEVEDPVDSDGEVLGFENLVFSIFEFVHALLENSKFKSTVKKALPELIYYIILYMQITEEQIKVWTANPQQFVEDEDDDTFSYTVRIAAQDLLLAVATDFQNESAAALAAAATRHLQEAEQTKNSGTEHWWKIHEACMLALGSVKAIITDSVKNGRIHFDMHGFLTNVILADLNLSVSPFLLGRALWAASRFTVAMSPELIQQFLQATVSGLHETQPPSVRISAVRAIWGYCDQLKVSESTHVLQPFLPSILDGLIHLAAQFSSEVLNLVMETLCIVCTVDPEFTASMESKICPFTIAIFLKYSNDPVVASLAQDIFKELSQIEACQGPMQMRLIPTLVSIMQAPADKIPAGLCATAIDILTTVVRNTKPPLSQLLICQAFPAVAQCTLHTDDNATMQNGGECLRAYVSVTLEQVAQWHDEQGHNGLWYVMQVVSQLLDPRTSEFTAAFVGRLVSTLISKAGRELGENLDQILRAILSKMQQAETLSVMQSLIMVFAHLVHTQLEPLLEFLCSLPGPTGKPALEFVMAEWTSRQHLFYGQYEGKVSSVALCKLLQHGINADDKRLQDIRVKGEEIYSMDEGIRTRSKSAKNPERWTNIPLLVKILKLIINELSNVMEANAARQATPAEWSQDDSNDMWEDQEEEEEEEEDGLAGQLLSDILATSKYEEDYYEDDEEDDPDALKDPLYQIDLQAYLTDFLCQFAQQPCYIMFSGHLNDNERRVLQTIGI", "length": 1041 }, "evidence": [ { "id": "F1NRZ6", "url": "https://omabrowser.org/oma/group/F1NRZ6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nuclear envelope", "id": "GO:0005635", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005635", "evidence": [ { "database": "UniProtKB", "id": "F1NRZ6", "url": "https://www.uniprot.org/uniprotkb/F1NRZ6" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "F1NRZ6", "url": "https://www.uniprot.org/uniprotkb/F1NRZ6" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F1NRZ6", "url": "https://www.uniprot.org/uniprotkb/F1NRZ6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "small GTPase binding", "id": "GO:0031267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031267", "evidence": [ { "database": "UniProtKB", "id": "F1NRZ6", "url": "https://www.uniprot.org/uniprotkb/F1NRZ6" } ], "pmid": "" }, { "name": "histone binding", "id": "GO:0042393", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042393", "evidence": [ { "database": "UniProtKB", "id": "F1NRZ6", "url": "https://www.uniprot.org/uniprotkb/F1NRZ6" } ], "pmid": "" }, { "name": "nuclear import signal receptor activity", "id": "GO:0061608", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061608", "evidence": [ { "database": "UniProtKB", "id": "F1NRZ6", "url": "https://www.uniprot.org/uniprotkb/F1NRZ6" } ], "pmid": "" }, { "name": "histone chaperone activity", "id": "GO:0140713", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140713", "evidence": [ { "database": "UniProtKB", "id": "F1NRZ6", "url": "https://www.uniprot.org/uniprotkb/F1NRZ6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "protein import into nucleus", "id": "GO:0006606", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006606", "evidence": [ { "database": "UniProtKB", "id": "F1NRZ6", "url": "https://www.uniprot.org/uniprotkb/F1NRZ6" } ], "pmid": "" }, { "name": "proteasome localization", "id": "GO:0031144", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031144", "evidence": [ { "database": "UniProtKB", "id": "F1NRZ6", "url": "https://www.uniprot.org/uniprotkb/F1NRZ6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 312, "end_pos": 314, "annotation": "n_glycosylation_sequon" }, { "start_pos": 416, "end_pos": 418, "annotation": "n_glycosylation_sequon" }, { "start_pos": 488, "end_pos": 490, "annotation": "n_glycosylation_sequon" }, { "start_pos": 708, "end_pos": 710, "annotation": "n_glycosylation_sequon" }, { "start_pos": 933, "end_pos": 935, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1NRZ6-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 1040, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1NRZ6-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1NRZ6" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 260 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 312, "end_pos": 314 }, { "start_pos": 416, "end_pos": 418 }, { "start_pos": 488, "end_pos": 490 }, { "start_pos": 708, "end_pos": 710 }, { "start_pos": 933, "end_pos": 935 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { 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"sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1NRZ9-1", "uniprot_ac": "F1NRZ9", "uniprot_id": "F1NRZ9_CHICK", "mass": { "chemical_mass": 67966.0, "monoisotopic_mass": 67966.0 }, "refseq": { "ac": "XP_015130850", "name": "proline dehydrogenase 1, mitochondrial", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015130850" }, "gene_names": [ { "name": "PRODH", "type": "recommended", "evidence": [ { "id": "F1NRZ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NRZ9" } ] }, { "name": "PRODH", "type": "synonym", "evidence": [ { "id": "XP_015130850", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015130850" } ] } ], "protein_names": [ { "name": "Proline dehydrogenase", "type": "recommended", "evidence": [ { "id": "F1NRZ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NRZ9/entry#names_and_taxonomy" } ] }, { "name": "1.5.5.2", "type": "synonym", "evidence": [ { "id": "F1NRZ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NRZ9/entry#names_and_taxonomy" } ] }, { "name": "proline dehydrogenase 1, mitochondrial", "type": "synonym", "evidence": [ { "id": "XP_015130850", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015130850" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052546.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 1, 2022 this sequence version replaced XP_015130850.3. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015130850", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015130850" } ] }, { "annotation": "Converts proline to delta-1-pyrroline-5-carboxylate.", "evidence": [ { "database": "UniProtKB", "id": "F1NRZ9", "url": "https://www.uniprot.org/uniprotkb/F1NRZ9#function" }, { "database": "UniProtKB", "id": "RU364054", "url": "https://www.uniprot.org/uniprotkb/RU364054#function" }, { "database": "UniProtKB", "id": "ARBA00057042", "url": "https://www.uniprot.org/uniprotkb/ARBA00057042#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NRZ9", "url": "https://www.uniprot.org/uniprotkb/F1NRZ9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PRODH", "url": "https://www.uniprot.org/uniprotkb/F1NRZ9", "locus": {} } ], "crossref": [ { "id": "F1NRZ9", "url": "https://alphafold.ebi.ac.uk/entry/F1NRZ9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000007728", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000007728", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "770734", "url": "https://www.ncbi.nlm.nih.gov/gene/770734", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002872", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002872", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015659", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015659", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029041", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029041", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:770734", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:770734", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "GPLKKYH", "url": "https://omabrowser.org/oma/group/GPLKKYH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1NRZ9", "url": "https://www.orthodb.org/?gene=F1NRZ9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13914", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13914", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13914:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13914:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01619", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01619", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-70688", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-70688", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_015130850", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015130850", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "23784", "url": "https://www.rhea-db.org/rhea/23784", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "F1NRZ9", "url": "https://www.uniprot.org/uniprotkb/F1NRZ9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NRZ9-1", "url": "https://www.uniprot.org/uniprotkb/F1NRZ9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MALPSAVRALHASAARVGAPRSVPRGAAPPLPASGKGGTRPVPPPVAPRGAAPTVDFGDPQEAFRSKSSAELLRGLLVLGLCAVGPLVEHNRELLQLGKRVLGQALFERLMKMTFYGQFVAGEDQEAIKPLIRRNRAFGVGAVLDYSVEEDLSPARAERQELASCTSAAEKEPGGAERREKQFRAHRGFGDRRDGVVSARTYFYADEAKCDQHMETFLSCIDASSGSSEDGFSAIKLTALGRPQFLLQFSEVLVKWRRFFHQMAAEQGQGGRAALEMRLEVEKLQEALAKLGVATKAESQHWFTGENVGESGTVDLLDWNSLIDSRTKLSKLLLVPNIKTRQLEPLLSHFTEEEELQMKRMLQRMDVLAKRATETGVRLMVDAEQSYFQPAISRLTLEMQRRFNRERAVIFNTHQCYLKEAYDNVSVDVELSRREGWHFGTKLVRGAYMEQERERAAKIGYEDPINPTYEKTNEMYHRCLDYVLEEIKHSRKANVMVATHNEDTVKFTLRRMMELGIHPSEKKVCFGQLLGMCDQITFPLGQAGFPVYKYVPYGPVDEVLPYLSRRAQENRGFMQRANQERDLLWREFKRRLFAGTIFSTNP", "length": 602, "header": "tr|F1NRZ9-1|F1NRZ9_CHICK Isoform 1 of Proline dehydrogenase OS=Gallus gallus OX=9031 GN=PRODH PE=1 SV=3 CANONICAL=F1NRZ9-1" }, "isoforms": [ { "isoform_ac": "F1NRZ9-1", "url": "https://www.uniprot.org/uniprotkb/F1NRZ9/entry#F1NRZ9-1", "sequence": { "sequence": "MALPSAVRALHASAARVGAPRSVPRGAAPPLPASGKGGTRPVPPPVAPRGAAPTVDFGDPQEAFRSKSSAELLRGLLVLGLCAVGPLVEHNRELLQLGKRVLGQALFERLMKMTFYGQFVAGEDQEAIKPLIRRNRAFGVGAVLDYSVEEDLSPARAERQELASCTSAAEKEPGGAERREKQFRAHRGFGDRRDGVVSARTYFYADEAKCDQHMETFLSCIDASSGSSEDGFSAIKLTALGRPQFLLQFSEVLVKWRRFFHQMAAEQGQGGRAALEMRLEVEKLQEALAKLGVATKAESQHWFTGENVGESGTVDLLDWNSLIDSRTKLSKLLLVPNIKTRQLEPLLSHFTEEEELQMKRMLQRMDVLAKRATETGVRLMVDAEQSYFQPAISRLTLEMQRRFNRERAVIFNTHQCYLKEAYDNVSVDVELSRREGWHFGTKLVRGAYMEQERERAAKIGYEDPINPTYEKTNEMYHRCLDYVLEEIKHSRKANVMVATHNEDTVKFTLRRMMELGIHPSEKKVCFGQLLGMCDQITFPLGQAGFPVYKYVPYGPVDEVLPYLSRRAQENRGFMQRANQERDLLWREFKRRLFAGTIFSTNP", "length": 602, "header": "tr|F1NRZ9-1|F1NRZ9_CHICK Isoform 1 of Proline dehydrogenase OS=Gallus gallus OX=9031 GN=PRODH PE=1 SV=3 CANONICAL=F1NRZ9-1" }, "locus": { "chromosome": "15", "start_pos": 10125231, "end_pos": 10117111, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010000276.1", "url": "https://www.ensembl.org/id/ENSGALT00010000276.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010000144.1", "url": "https://www.ensembl.org/id/ENSGALP00010000144.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "gga:770734", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:770734", "resource": "KEGG Pathway" }, { "id": "R-GGA-70688", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-70688", "resource": "Reactome", "description": "Proline catabolism" } ], "orthologs": [ { "uniprot_canonical_ac": "F1MAR6-1", "protein_name": "Proline dehydrogenase", "gene_name": "Prodh1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGRDQGVIQGVASPMYLSFLSALTGSAMALKRVFLLRSVAPRVAALSTKPRAQEQPPANPEALRGCGAAEAVRPPVPAVDFTNTQEAYRSRRSWELARNLLVLRLCASPVLLAHHEQLFQVARKLLGQRMFERLMKMTFYGHFVAGEDQESIRPLIRHNKAFGVGFILDYGVEEDLSPEEAERKEMESCTSEAERDGSGANKREKQYQVHPAFGDRRDGVISARTYFYASEAKCDNYMENLLQCIEASGGASDGGFSAIKLTALGRPQFLLQFSDVLTRWRQFFHQMAAEQGQAGRPAVDTKLEVAVLQESIAKMGISSRAEIERWFTPETLGVSGTVDLLDWNSLIDSRTQLSRHLVVPNVQTGQLEPLLSRFTEEEEQQMKRMLQRMDVLAKRAREAGVRLMIDAEQSYFQPAISRLTLEMQRRFNVDKPFIFNTFQCYLKDAYDNVTIDMELSRREGWCFGAKLVRGAYMAQERARAVEIGYEDPINPTYEATNAMYHRCLNYVLEELKHSTKAEVMVASHNEDTVSFTLCRMKELGLHPADGQVCFGQLLGMCDQISFPLGQAGFPVYKYVPYGPVMEVLPYLSRRALENSSIMKGAQRERQLLWQELCRRLRTGSLFHHPA", "length": 626 }, "evidence": [ { "id": "F1NRZ9", "url": "https://omabrowser.org/oma/group/F1NRZ9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q04499-1", "protein_name": "Proline dehydrogenase 1, mitochondrial", "gene_name": "slgA", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MALLRSLSAQRTAISLVYGRNSSKSSNSVAVAACRSFHQRGSGSTSIAGEGAASESTRGVNGARFLHSGDRPLQASTLVQPEVVSSETVKRSMKQESSQEKNPSPAGSPQRDPLDVSFNDPIAAFKSKTTGELIRAYLVYMICSSEKLVEHNMTLMKLARNLLGQKLFVLLMKSSFYGHFVAGENRHTIVPALERLRSFGVKPILDYSVEEDITQEEAEKREVESSVSSAGDKKEEGSMPQYHVDKSFADRRYKVSSARTYFYLNEATCERNMEIFIKCLEAVSDDDRKAPRAVATGATFGTGITAIKLTALGRPQLLLQLSEVIMRTRKYMEDMVGGQGNVLTHHKTIKDLEKYYATLGDNKDVKEFLNNVTSDKEGILHLFPWSGIVDEDSQLSDTFRVPDPQTGQMRRLISQIPPKEEEMFRNMIRRLNTIVKAAADLDVRIMVDAEQTYFQPAISRITLEMMRKYNKDKAIVFNTYQCYLRETFREVNTDLEQAKRQNFYFGAKLVRGAYMDQERDRAKSLGYPDPVNPTFEATTDMYHRTLSECLRRIKLMKDCDDDARKIGIMVASHNEDTVRFAIQQMKEIGISPEDKVICFGQLLGMCDYITFPLGQAGYSAYKYIPYGPVEEVLPYLSRRAQENKGVLKKIKKEKRLLLSEIRRRLMRGQLFYKPKGNYVPI", "length": 681 }, "evidence": [ { "id": "F1NRZ9", "url": "https://omabrowser.org/oma/group/F1NRZ9/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q86H28-1", "protein_name": "Proline dehydrogenase 1, mitochondrial", "gene_name": "prodh", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIKNTVRIINKNSNTFINIRNNNNNNINSSLKSGFGTIKRFNTTLNHNSSNSNIQTPISINSTIINNNNNSNNNNSNNIINNDLNVVKFSTISTPNSILDTLNENHSNQTNNVNNKNYNNNNNNFEKDDKFGPPNNQNNNKLDLDTSKLYVSKSTGELFFTFMILKVCSINFISDNSQKFLNLFEKLGLSKPLNFFIKYSFFKQFCAGETIRETEIFTEKLNKLGIGTILDYAIEELAGSSEGFDSVAENICETIRVAAKNPTNSFSCVKFTGLVTPSVLEKMNTLVSNVTTNVSELPIESFNSPLDFYLNQSSSLMKQGSEPLLTSKDIKEIKEFFNRMDKIFQLCHQRGVPILVDAEQSYYQVAIHHLTMSYSIKYNKEKPIIYNTYQMYLVNGMNVLKQHFELSSSQKFNFKLGAKIVRGAYMVTESERSQRLSTENPVLPTIQDTHKSYNTALDFLLNQIKSDPNSIGLMIASHNEDSINLGTKLIKQYKIDPTNPNIQFGQLFGMADFLSFNLVDQHQRIFKYVPFGPVEEVLPYLIRRMHENKGFIGSNSDKELFYLKKEIKRRLF", "length": 572 }, "evidence": [ { "id": "F1NRZ9", "url": "https://omabrowser.org/oma/group/F1NRZ9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q9WU79-1", "protein_name": "Proline dehydrogenase 1, mitochondrial", "gene_name": "Prodh", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALKRVFLLRSVAPRVAALSTKPQAQEQPPASPEALRGCGAAKAVRPPVPAVDFTNTQEAYRSRRSWELVRNLLVLRLCASPVLLAHHEQLFQVARKLLGQRMFERLMKMTFYGHFVAGEDQESIRPLIRHNKAFGVGFILDYGVEEDLSPEEAERKEMESCTSEAERDGSGANKREKQYQVHPAFGDRRDGVISARTYFYANEAKCDNYMENLLQCIKASGGASDGGFSAIKLTALGRPQFLLQFSDVLTRWRRFFHQMAAEQGQAGRAAVDTKLEVAVLQDSIAKMGIASRAEIEGWFTPETLGVSGTVDLLDWNSLIDSRTRLSRHLVVPNVQTGQLEPLLSRFTEEEEQQMKRMLQRMDVLAKKAKEAGVRLMIDAEQSYFQPAISRLTLEMQRRFNVDKPFIFNTFQCYLKDAYDNVTLDMELARREGWCFGAKLVRGAYMAQERVRAAEIGYEDPINPTYEATNAMYHRCLNYVLEELKHSTKAEVMVASHNEDTVHFTLCRMKEIGLHPADGQVCFGQLLGMCDQISFPLGQAGFPVYKYVPYGPVMEVLPYLSRRALENSSIMKGAQRERQLLWQELRRRLRTGSLFHHPA", "length": 599 }, "evidence": [ { "id": "F1NRZ9", "url": "https://omabrowser.org/oma/group/F1NRZ9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "F1NRZ9", "url": "https://www.uniprot.org/uniprotkb/F1NRZ9" } ], "pmid": "" }, { "name": "mitochondrial matrix", "id": "GO:0005759", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005759", "evidence": [ { "database": "UniProtKB", "id": "F1NRZ9", "url": "https://www.uniprot.org/uniprotkb/F1NRZ9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "FAD binding", "id": "GO:0071949", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071949", "evidence": [ { "database": "UniProtKB", "id": "F1NRZ9", "url": "https://www.uniprot.org/uniprotkb/F1NRZ9" } ], "pmid": "" }, { "name": "proline dehydrogenase activity", "id": "GO:0004657", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004657", "evidence": [ { "database": "UniProtKB", "id": "F1NRZ9", "url": "https://www.uniprot.org/uniprotkb/F1NRZ9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "L-proline catabolic process to L-glutamate", "id": "GO:0010133", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010133", "evidence": [ { "database": "UniProtKB", "id": "F1NRZ9", "url": "https://www.uniprot.org/uniprotkb/F1NRZ9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 424, "end_pos": 426, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "23784", "name": "", "equation": "L-proline + a quinone = (S)-1-pyrroline-5-carboxylate + a quinol + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0X4K6-1", "F1NRZ9-1" ], "evidence": [ { "id": "23784", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/23784" } ] }, { "id": "R-GGA-70670", "name": "PRODH oxidises L-Pro to 1PYR-5COOH", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "mitochondrial inner membrane, mitochondrial matrix", "input_participant_list": [ "R-ALL-379717", "R-ALL-113597" ], "output_participant_list": [ "R-ALL-113590" ], "enzyme_list": [ "F1NRZ9-1" ], "evidence": [ { "id": "R-GGA-70670", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-70670" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-113590", "participant_name": "1PYR-5COOH [mitochondrial matrix]", "crossref": [ { "id": "C03912", "database": "COMPOUND", "url": "" }, { "id": "17388", "database": "ChEBI", "url": "" }, { "id": "ZINC000003870284", "database": "ZINC", "url": "" }, { "id": "8144614", "database": "PubChem Substance", "url": "" } ] }, { "participant_id": "R-ALL-113597", "participant_name": "FAD [mitochondrial inner membrane]", "crossref": [ { "id": "57692", "database": "ChEBI", "url": "" }, { "id": "ZINC000008215434", "database": "ZINC", "url": "" }, { "id": "ZINC000195756838", "database": "ZINC", "url": "" }, { "id": "C00016", "database": "COMPOUND", "url": "" } ] }, { "participant_id": "R-ALL-379717", "participant_name": "L-Pro [mitochondrial matrix]", "crossref": [ { "id": "60039", "database": "ChEBI", "url": "" }, { "id": "ZINC000000895360", "database": "ZINC", "url": "" }, { "id": "C00148", "database": "COMPOUND", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A0A8V0X4K6", "gene_name": "PRODH2", "activity": [ { "ec_number": "1.5.5.2", "activity": "L-proline + a quinone = (S)-1-pyrroline-5-carboxylate + a quinol + H(+).", "evidence": [ { "id": "A0A8V0X4K6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X4K6" } ] }, { "ec_number": "1.5.5.2", "activity": "", "evidence": [ { "id": "A0A8V0X4K6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X4K6" } ] } ] }, { "uniprot_ac": "F1NRZ9", "gene_name": "PRODH", "activity": [ { "ec_number": "1.5.5.2", "activity": "L-proline + a quinone = (S)-1-pyrroline-5-carboxylate + a quinol + H(+).", "evidence": [ { "id": "F1NRZ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NRZ9" } ] }, { "ec_number": "1.5.5.2", "activity": "", "evidence": [ { "id": "F1NRZ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NRZ9" } ] } ] } ], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1NRZ9-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 602, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1NRZ9-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1NRZ9" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1NRZ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NRZ9" }, { "id": "PF01619", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01619" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Proline dehydrogenase", "eco_id": "ECO_0000259", "start_pos": 297, "end_pos": 576, "start_aa": "Ala", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "1.5.5.2", "ec_name": "L-proline + a quinone = (S)-1-pyrroline-5-carboxylate + a quinol + H(+).", "evidence": [ { "id": "1.5.5.2", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:1.5.5.2" }, { "id": "1.5.5.2", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=1.5.5.2" } ] } ], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 424, "end_pos": 426 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1NS02-1", "uniprot_ac": "F1NS02", "uniprot_id": "F1NS02_CHICK", "mass": { "chemical_mass": 81477.0, "monoisotopic_mass": 81477.0 }, "refseq": { "ac": "XP_015154634", "name": "sodium-dependent neutral amino acid transporter SLC6A17", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015154634" }, "gene_names": [ { "name": "SLC6A17", "type": "recommended", "evidence": [ { "id": "F1NS02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NS02" } ] }, { "name": "SLC6A17", "type": "synonym", "evidence": [ { "id": "XP_015154634", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015154634" } ] } ], "protein_names": [ { "name": "Transporter", "type": "recommended", "evidence": [ { "id": "F1NS02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NS02/entry#names_and_taxonomy" } ] }, { "name": "sodium-dependent neutral amino acid transporter SLC6A17", "type": "synonym", "evidence": [ { "id": "XP_015154634", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015154634" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052557.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015154634", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015154634" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NS02", "url": "https://www.uniprot.org/uniprotkb/F1NS02" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SLC6A17", "url": "https://www.uniprot.org/uniprotkb/F1NS02", "locus": { "chromosome": "26", "start_pos": 1396691, "end_pos": 1385574, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010025559", "url": "https://www.ensembl.org/id/ENSGALG00010025559" } ] } } ], "crossref": [ { "id": "F1NS02", "url": "https://alphafold.ebi.ac.uk/entry/F1NS02", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000000394", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000000394", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd11521", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11521", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "419805", "url": "https://www.ncbi.nlm.nih.gov/gene/419805", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000175", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000175", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002438", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002438", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037272", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037272", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:419805", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419805", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DYTEMYK", "url": "https://omabrowser.org/oma/group/DYTEMYK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A8B1", "url": "https://www.orthodb.org/?gene=A0A8V1A8B1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NS02", "url": "https://www.orthodb.org/?gene=F1NS02", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11616", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11616", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11616:SF102", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11616:SF102", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00209", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00209", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015154634", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015154634", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1A8B1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8B1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A8B1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8B1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NS02", "url": "https://www.uniprot.org/uniprotkb/F1NS02", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NS02-1", "url": "https://www.uniprot.org/uniprotkb/F1NS02-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPKNSKVTQREHSSEHVTESVADLLAHEEPVDYKRSVLNVTGEAWDKQKDGEEELDAENRPAWNSKLQYILAQIGYSVGLGNVWRFPYLCQKNGGGAYLVPYLVLLIIIGLPLFFLELAVGQRIRRGSIGVWNYICPRLGGIGYASCLVCFFVGLYYNVIIGWSIFYFFKSFQYPLPWSECPIVRNGSVAVVETECERSSATTYFWYREALDISNSISESGGLNWKMTLCLLVAWSLVGLAMIKGIQSSGKVMYFSSLFPYVVLVCFLVRGLLLRGAVDGIMHMFTPKLDKMLDPQVWREAATQVFFALGLGFGGVIAFSSYNKQDNNCHFDATLVSFINFFTSVLATLVVFAVLGFKANIMNEKCVVENAEKILGYLNTNVLSHDLIPPHVNFSHLTAKDYNEMYRVIMTVKEGHFKELGLDACLLEDELDKSVQGTGLAFIAFTEAMTHFPASPFWSVMFFLMLINLGLGSMIGTMSGITTPIIDTFKVRKEVFTVGCCIFAFVVGLIFVQRSGNYFVTMFDDYSATLPLTVVVILENIAVAWIYGTKKFMQELTEMLGFRPYQFYYYTWKYVSPICMAVLMTASIIQLGVSPPGYSAWIREEAAEKFLFYPTWAMAILISLIILASLPLPLVFILRQFHLVSDGSNTLSVTYKKGRMMKDISNLEDNDETRFILSKVPSETPSPMPTHRSYLGPGSNSPMEMSSAPNGRYGSGYLTAGTPESEL", "length": 727, "header": "tr|F1NS02-1|F1NS02_CHICK Isoform 1 of Transporter OS=Gallus gallus OX=9031 GN=SLC6A17 PE=3 SV=5 CANONICAL=F1NS02-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A8B1-1", "url": "https://www.uniprot.org/uniprotkb/F1NS02/entry#A0A8V1A8B1-1", "sequence": { "sequence": "MPKNSKVTQREHSSEHVTESVADLLAHEEPVDYKRSVLNVTGEAWDKQKDGEEELDAENRPAWNSKLQYILAQIGYSVGLGNVWRFPYLCQKNGGGAYLVPYLVLLIIIGLPLFFLELAVGQRIRRGSIGVWNYICPRLGGIGYASCLVCFFVGLYYNVIIGWSIFYFFKSFQYPLPWSECPIVRNGSVAVVETECERSSATTYFWYREALDISNSISESGGLNWKMTLCLLVAWSLVGLAMIKGIQSSGKLDKMLDPQVWREAATQVFFALGLGFGGVIAFSSYNKQDNNCHFDATLVSFINFFTSVLATLVVFAVLGFKANIMNEKCVVENAEKILGYLNTNVLSHDLIPPHVNFSHLTAKDYNEMYRVIMTVKEGHFKELGLDACLLEDELDKSVQGTGLAFIAFTEAMTHFPASPFWSVMFFLMLINLGLGSMIGTMSGITTPIIDTFKVRKEVFTVGCCIFAFVVGLIFVQRSGNYFVTMFDDYSATLPLTVVVILENIAVAWIYGTKKFMQELTEMLGFRPYQFYYYTWKYVSPICMAVLMTASIIQLGVSPPGYSAWIREEAAEKFLFYPTWAMAILISLIILASLPLPLVFILRQFHLVSDGSNTLSVTYKKGRMMKDISNLEDNDETRFILSKVPSETPSPMPTHRSYLGPGSNSPMEMSSAPNGRYGSGYLTAGTPESEL", "length": 690, "header": "tr|A0A8V1A8B1-1|A0A8V1A8B1_CHICK Computationally mapped isoform of Transporter OS=Gallus gallus OX=9031 GN=SLC6A17 PE=3 SV=1 CANONICAL=F1NS02-1" }, "locus": { "chromosome": "26", "start_pos": 1395687, "end_pos": 1389038, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010062358.1", "url": "https://www.ensembl.org/id/ENSGALT00010062358.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038551.1", "url": "https://www.ensembl.org/id/ENSGALP00010038551.1" } ] } }, { "isoform_ac": "F1NS02-1", "url": "https://www.uniprot.org/uniprotkb/F1NS02/entry#F1NS02-1", "sequence": { "sequence": "MPKNSKVTQREHSSEHVTESVADLLAHEEPVDYKRSVLNVTGEAWDKQKDGEEELDAENRPAWNSKLQYILAQIGYSVGLGNVWRFPYLCQKNGGGAYLVPYLVLLIIIGLPLFFLELAVGQRIRRGSIGVWNYICPRLGGIGYASCLVCFFVGLYYNVIIGWSIFYFFKSFQYPLPWSECPIVRNGSVAVVETECERSSATTYFWYREALDISNSISESGGLNWKMTLCLLVAWSLVGLAMIKGIQSSGKVMYFSSLFPYVVLVCFLVRGLLLRGAVDGIMHMFTPKLDKMLDPQVWREAATQVFFALGLGFGGVIAFSSYNKQDNNCHFDATLVSFINFFTSVLATLVVFAVLGFKANIMNEKCVVENAEKILGYLNTNVLSHDLIPPHVNFSHLTAKDYNEMYRVIMTVKEGHFKELGLDACLLEDELDKSVQGTGLAFIAFTEAMTHFPASPFWSVMFFLMLINLGLGSMIGTMSGITTPIIDTFKVRKEVFTVGCCIFAFVVGLIFVQRSGNYFVTMFDDYSATLPLTVVVILENIAVAWIYGTKKFMQELTEMLGFRPYQFYYYTWKYVSPICMAVLMTASIIQLGVSPPGYSAWIREEAAEKFLFYPTWAMAILISLIILASLPLPLVFILRQFHLVSDGSNTLSVTYKKGRMMKDISNLEDNDETRFILSKVPSETPSPMPTHRSYLGPGSNSPMEMSSAPNGRYGSGYLTAGTPESEL", "length": 727, "header": "tr|F1NS02-1|F1NS02_CHICK Isoform 1 of Transporter OS=Gallus gallus OX=9031 GN=SLC6A17 PE=3 SV=5 CANONICAL=F1NS02-1" }, "locus": { "chromosome": "26", "start_pos": 1395687, "end_pos": 1389038, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010062354.1", "url": "https://www.ensembl.org/id/ENSGALT00010062354.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038548.1", "url": "https://www.ensembl.org/id/ENSGALP00010038548.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:419805", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419805", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "F1N1Q2-1", "protein_name": "Transporter", "gene_name": "SLC6A17", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MPKNSKVTQREHSNEHVTESVADLLALEEPVDYKQSVLNVAGEAGGKQKAAEEELDAEDRPAWNSKLQYILAQIGFSVGLGNIWRFPYLCQKNGGGAYLVPYLVLLIIIGIPLFFLELAVGQRIRRGSIGVWHYVCPRLGGIGFSSCIVCLFVGLYYNVIIGWSIFYFFKSFQYPLPWSECPVSRNGTVAVVEAECEKSSATTYFWYREALDISNSISESGGLNWKMTLCLLVAWSIVGMAVVKGIQSSGKVMYFSSLFPYVVLACFLVRGLLLRGAIDGILHMFTPKLDKMLDPQVWREAATQVFFALGLGFGGVIAFSSYNKQDNNCHFDAALVSFINFFTSVLATLVVFAVLGFKANIMNEKCVVENAEKILGYLNNDVLSRALIPPHVNFSHLTTKDYAEMYKVIKTVKEDHFSALGLDPCLLEDELDKSVQGTGLAFIAFTEAMTHFPASPFWSVMFFLMLINLGLGSMIGTMAGITTPIIDTFKVPKEMFTVGCCVFAFFVGLLFVQRSGNYFVTMFDDYSATLPLTVIVILENVAVAWIYGTKKFMQELTEMLGFQPYRFYFYMWKFVSPLCMAVLTTASIIQLGVTPPGYSAWIREEAAERYLYFPNWAMAILITLIVVAVLPIPVVFVLRHFHLLSDGSNTLSVSYKKGRMMKDISNLEENDETRFILSKVPSEAPSPMPTHRSYLGPGSTSPLETSGNPNGRYGSGYLLAGTPESEL", "length": 727 }, "evidence": [ { "id": "F1NS02", "url": "https://omabrowser.org/oma/group/F1NS02/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1S617-1", "protein_name": "Transporter", "gene_name": "SLC6A17", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MPKNSKVTQREHSSEHVTESVADLLALEEPVDYKQSVLNVAGEAGGKQKAAEEELDAEDRPAWNSKLQYILAQIGFSVGLGNIWRFPYLCQKNGGGAYLVPYLVLLIIIGIPLFFLELAVGQRIRRGSIGVWHYVCPRLGGIGFSSCIVCLFVGLYYNVIIGWSIFYFFKSFQYPLPWSECPVIRNGTVAVVEPECEKSSATTYFWYREALDISNSISESGGLNWKMTLCLLVAWSIVGMAVVKGIQSSGKVMYFSSLFPYVVLACFLVRGLLLRGAIDGILHMFTPKLDKMLDPQVWREAATQVFFALGLGFGGVIAFSSYNKQDNNCHFDAALVSFINFFTSVLATLVVFAVLGFKANIMNEKCVVENAEKILGYLNTDVLSRALIPPHVNFSHLSARDYAEMYKVIRTVKEDRFPALGLDPCLLEDELDKSVQGTGLAFIAFTEAMTHFPASPFWSVMFFLMLINLGLGSMIGTMAGITTPIIDTFKVPKEMFTVGCCVFAFFVGLLFVQRSGNYFVTMFDDYSATLPLTLIVILENVAVAWIYGTKKFMQELTEMLGFRPYRFYFYMWKFVSPLCMAVLTTASIIQLGVTPPGYSAWIKEEAAERYLYFPNWAMALLITLIVLAVLPIPVGFVLRHFHLLSDGSNTLSVSYKKGRMMKEISNLEENDETRFILSKVPSEAPSPMPTHRSYLGPGSTSPLETSGNPNGRYGSGYLLASTPESEL", "length": 727 }, "evidence": [ { "id": "F1NS02", "url": "https://omabrowser.org/oma/group/F1NS02/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P31662-1", "protein_name": "Sodium-dependent neutral amino acid transporter SLC6A17", "gene_name": "Slc6a17", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPKNSKVTQREHSNEHVTESVADLLALEEPVDYKQSVLNVAGETGGKQKVAEEELDAEDRPAWNSKLQYILAQIGFSVGLGNIWRFPYLCQKNGGGAYLVPYLVLLIIIGIPLFFLELAVGQRIRRGSIGVWHYVCPRLGGIGFSSCIVCLFVGLYYNVIIGWSVFYFFKSFQYPLPWSECPVIRNGTVAVVEPECEKSSATTYFWYREALDISNSISESGGLNWKMTVCLLVAWSIVGMAVVKGIQSSGKVMYFSSLFPYVVLACFLVRGLLLRGAVDGILHMFTPKLDKMLDPQVWREAATQVFFALGLGFGGVIAFSSYNKQDNNCHFDAALVSFINFFTSVLATLVVFAVLGFKANIMNEKCVVENAEKILGYLNSNVLSRDLIPPHVNFSHLTTKDYSEMYNVIMTVKEKQFSALGLDPCLLEDELDKSVQGTGLAFIAFTEAMTHFPASPFWSVMFFLMLINLGLGSMIGTMAGITTPIIDTFKVPKEMFTVGCCVFAFFVGLLFVQRSGNYFVTMFDDYSATLPLTVIVILENIAVAWIYGTKKFMQELTEMLGFRPYRFYFYMWKFVSPLCMAVLTTASIIQLGVSPPGYSAWIKEEAAERYLYFPNWAMALLITLIAVATLPIPVVFILRHFHLLSDGSNTLSVSYKKGRMMKDISNLEENDETRFILSKVPSEAPSPMPTHRSYLGPGSTSPLESSSHPNGRYGSGYLLASTPESEL", "length": 727 }, "evidence": [ { "id": "F1NS02", "url": "https://omabrowser.org/oma/group/F1NS02/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8BJI1-1", "protein_name": "Sodium-dependent neutral amino acid transporter SLC6A17", "gene_name": "Slc6a17", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPKNSKVTQREHSNEHVTESVADLLALEEPVDYKQSVLNVAGETGGKQKVAEEELDTEDRPAWNSKLQYILAQIGFSVGLGNIWRFPYLCQKNGGGAYLVPYLVLLIIIGIPLFFLELAVGQRIRRGSIGVWHYVCPRLGGIGFSSCIVCLFVGLYYNVIIGWSVFYFFKSFQYPLPWSECPVIRNGTVAVVEPECEKSSATTYFWYREALDISNSISESGGLNWKMTLCLLVAWSIVGMAVVKGIQSSGKVMYFSSLFPYVVLACFLVRGLLLRGAVDGILHMFTPKLDKMLDPQVWREAATQVFFALGLGFGGVIAFSSYNKQDNNCHFDAALVSFINFFTSVLATLVVFAVLGFKANIMNEKCVVENAEKILGYLNSNVLSRDLIPPHVNFSHLTTKDYSEMYSVIMTVKEKQFPALGLDPCLLEDELDKSVQGTGLAFIAFTEAMTHFPASPFWSVMFFLMLINLGLGSMIGTMAGITTPIIDTFKVPKEMFTVGCCVFAFFVGLLFVQRSGNYFVTMFDDYSATLPLTVIVILENIAVAWIYGTKKFMQELTEMLGFQPYRFYFYMWKFVSPLCMAVLTTASIIQLGVSPPGYSAWIKEEAAERYLYFPNWAMALLITLIAVATLPIPVVFILRHFHLLSDGSNTLSVSYKKGRMMKDISNLEENDETRFILSKVPSEAPSPMPTHRSYLGPGSTSPLDNSNNPNGRYGSGYLLASTPESEL", "length": 727 }, "evidence": [ { "id": "F1NS02", "url": "https://omabrowser.org/oma/group/F1NS02/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9H1V8-1", "protein_name": "Sodium-dependent neutral amino acid transporter SLC6A17", "gene_name": "SLC6A17", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPKNSKVTQREHSSEHVTESVADLLALEEPVDYKQSVLNVAGEAGGKQKAVEEELDAEDRPAWNSKLQYILAQIGFSVGLGNIWRFPYLCQKNGGGAYLVPYLVLLIIIGIPLFFLELAVGQRIRRGSIGVWHYICPRLGGIGFSSCIVCLFVGLYYNVIIGWSIFYFFKSFQYPLPWSECPVVRNGSVAVVEAECEKSSATTYFWYREALDISDSISESGGLNWKMTLCLLVAWSIVGMAVVKGIQSSGKVMYFSSLFPYVVLACFLVRGLLLRGAVDGILHMFTPKLDKMLDPQVWREAATQVFFALGLGFGGVIAFSSYNKQDNNCHFDAALVSFINFFTSVLATLVVFAVLGFKANIMNEKCVVENAEKILGYLNTNVLSRDLIPPHVNFSHLTTKDYMEMYNVIMTVKEDQFSALGLDPCLLEDELDKSVQGTGLAFIAFTEAMTHFPASPFWSVMFFLMLINLGLGSMIGTMAGITTPIIDTFKVPKEMFTVGCCVFAFLVGLLFVQRSGNYFVTMFDDYSATLPLTLIVILENIAVAWIYGTKKFMQELTEMLGFRPYRFYFYMWKFVSPLCMAVLTTASIIQLGVTPPGYSAWIKEEAAERYLYFPNWAMALLITLIVVATLPIPVVFVLRHFHLLSDGSNTLSVSYKKGRMMKDISNLEENDETRFILSKVPSEAPSPMPTHRSYLGPGSTSPLETSGNPNGRYGSGYLLASTPESEL", "length": 727 }, "evidence": [ { "id": "F1NS02", "url": "https://omabrowser.org/oma/group/F1NS02/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "glycine transport", "id": "GO:0015816", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015816", "evidence": [ { "database": "UniProtKB", "id": "F1NS02", "url": "https://www.uniprot.org/uniprotkb/F1NS02" } ], "pmid": "" }, { "name": "L-leucine transport", "id": "GO:0015820", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015820", "evidence": [ { "database": "UniProtKB", "id": "F1NS02", "url": "https://www.uniprot.org/uniprotkb/F1NS02" } ], "pmid": "" }, { "name": "proline transport", "id": "GO:0015824", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015824", "evidence": [ { "database": "UniProtKB", "id": "F1NS02", "url": "https://www.uniprot.org/uniprotkb/F1NS02" } ], "pmid": "" }, { "name": "alanine transport", "id": "GO:0032328", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032328", "evidence": [ { "database": "UniProtKB", "id": "F1NS02", "url": "https://www.uniprot.org/uniprotkb/F1NS02" } ], "pmid": "" }, { "name": "brain development", "id": "GO:0007420", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007420", "evidence": [ { "database": "UniProtKB", "id": "F1NS02", "url": "https://www.uniprot.org/uniprotkb/F1NS02" } ], "pmid": "" }, { "name": "sodium ion transmembrane transport", "id": "GO:0035725", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035725", "evidence": [ { "database": "UniProtKB", "id": "F1NS02", "url": "https://www.uniprot.org/uniprotkb/F1NS02" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F1NS02", "url": "https://www.uniprot.org/uniprotkb/F1NS02" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "F1NS02", "url": "https://www.uniprot.org/uniprotkb/F1NS02" } ], "pmid": "" }, { "name": "synaptic vesicle", "id": "GO:0008021", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008021", "evidence": [ { "database": "UniProtKB", "id": "F1NS02", "url": "https://www.uniprot.org/uniprotkb/F1NS02" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "F1NS02", "url": "https://www.uniprot.org/uniprotkb/F1NS02" } ], "pmid": "" }, { "name": "symporter activity", "id": "GO:0015293", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015293", "evidence": [ { "database": "UniProtKB", "id": "F1NS02", "url": "https://www.uniprot.org/uniprotkb/F1NS02" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 186, "end_pos": 188, "annotation": "n_glycosylation_sequon" }, { "start_pos": 393, "end_pos": 395, "annotation": "n_glycosylation_sequon" }, { "start_pos": 39, "end_pos": 41, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1NS02-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 727, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1NS02-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1NS02" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 186, "end_pos": 188 }, { "start_pos": 393, "end_pos": 395 }, { "start_pos": 39, "end_pos": 41 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1NS09-1", "uniprot_ac": "F1NS09", "uniprot_id": "F1NS09_CHICK", "mass": { "chemical_mass": 36920.0, "monoisotopic_mass": 36920.0 }, "refseq": { "ac": "XP_417682", "name": "mitoferrin-1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_417682" }, "gene_names": [ { "name": "SLC25A37", "type": "recommended", "evidence": [ { "id": "F1NS09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NS09" } ] }, { "name": "SLC25A37", "type": "synonym", "evidence": [ { "id": "XP_417682", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_417682" } ] } ], "protein_names": [ { "name": "Mitoferrin-1", "type": "recommended", "evidence": [ { "id": "F1NS09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NS09/entry#names_and_taxonomy" } ] }, { "name": "Mitochondrial iron transporter 1", "type": "synonym", "evidence": [ { "id": "F1NS09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NS09/entry#names_and_taxonomy" } ] }, { "name": "Solute carrier family 25 member 37", "type": "synonym", "evidence": [ { "id": "F1NS09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NS09/entry#names_and_taxonomy" } ] }, { "name": "mitoferrin-1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_417682", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_417682" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052553.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 19, 2013 this sequence version replaced XP_417682.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_417682", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_417682" } ] }, { "annotation": "Mitochondrial iron transporter that specifically mediates iron uptake in developing erythroid cells, thereby playing an essential role in heme biosynthesis.", "evidence": [ { "database": "UniProtKB", "id": "F1NS09", "url": "https://www.uniprot.org/uniprotkb/F1NS09#function" }, { "database": "UniProtKB", "id": "ARBA00037061", "url": "https://www.uniprot.org/uniprotkb/ARBA00037061#function" }, { "database": "UniProtKB", "id": "A0A8V0ZCF2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCF2#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NS09", "url": "https://www.uniprot.org/uniprotkb/F1NS09" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SLC25A37", "url": "https://www.uniprot.org/uniprotkb/F1NS09", "locus": { "chromosome": "22", "start_pos": 1231348, "end_pos": 1242857, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010020244", "url": "https://www.ensembl.org/id/ENSGALG00010020244" } ] } } ], "crossref": [ { "id": "F1NS09", "url": "https://alphafold.ebi.ac.uk/entry/F1NS09", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000000378", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000000378", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "419530", "url": "https://www.ncbi.nlm.nih.gov/gene/419530", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002067", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002067", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018108", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018108", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023395", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023395", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:419530", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419530", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MYNSQHQ", "url": "https://omabrowser.org/oma/group/MYNSQHQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZCF2", "url": "https://www.orthodb.org/?gene=A0A8V0ZCF2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NS09", "url": "https://www.orthodb.org/?gene=F1NS09", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45758", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45758", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45758:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45758:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00153", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00153", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_417682", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_417682", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "28486", "url": "https://www.rhea-db.org/rhea/28486", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0ZCF2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCF2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZCF2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCF2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NS09", "url": "https://www.uniprot.org/uniprotkb/F1NS09", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NS09-1", "url": "https://www.uniprot.org/uniprotkb/F1NS09-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MELSCSVGGSTAAPPGPGPPGPIAAPSVPPPMEGEDYESLPSGASLGTHMLAGAVAGIMEHSVMYPVDSVKTRMQSLQPDPKAQYRSVYEALKKMVLTEGFWRPLRGINVTMLGAGPAHAMYFACYEKMKKSLSDTIQHGGNSHLANGIAGSVATLLHDAVMNPAEVVKQRMQMFNSPYKSVWQCVRTVQKTEGFGAFYRSYTTQLTMNVPFQAIHFITYEFMQERVNPHREYHPLSHVCSGAVAGAVAAAATTPLDVCKTLLNTQENTALSSLNITGHLSGMANAFRTVYQLGGIAGYFRGVQARVIYQIPSTAIAWSVYEFFKYFLTKHKLEKRTSL", "length": 339, "header": "tr|F1NS09-1|F1NS09_CHICK Isoform 1 of Mitoferrin-1 OS=Gallus gallus OX=9031 GN=SLC25A37 PE=3 SV=4 CANONICAL=F1NS09-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZCF2-1", "url": "https://www.uniprot.org/uniprotkb/F1NS09/entry#A0A8V0ZCF2-1", "sequence": { "sequence": "MLRAAALELSPNTGHVLLQLHSSVFTSCILSCKDLCNWTTTFTRMQSLQPDPKAQYRSVYEALKKMVLTEGFWRPLRGINVTMLGAGPAHAMYFACYEKMKKSLSDTIQHGGNSHLANGIAGSVATLLHDAVMNPAEVVKQRMQMFNSPYKSVWQCVRTVQKTEGFGAFYRSYTTQLTMNVPFQAIHFITYEFMQERVNPHREYHPLSHVCSGAVAGAVAAAATTPLDVCKTLLNTQENTALSSLNITGHLSGMANAFRTVYQLGGIAGYFRGVQARVIYQIPSTAIAWSVYEFFKYFLTKHKLEKRTSL", "length": 310, "header": "tr|A0A8V0ZCF2-1|A0A8V0ZCF2_CHICK Computationally mapped isoform of Mitoferrin-1 OS=Gallus gallus OX=9031 GN=SLC25A37 PE=3 SV=1 CANONICAL=F1NS09-1" }, "locus": { "chromosome": "22", "start_pos": 1239248, "end_pos": 1233914, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048862.1", "url": "https://www.ensembl.org/id/ENSGALT00010048862.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028884.1", "url": "https://www.ensembl.org/id/ENSGALP00010028884.1" } ] } }, { "isoform_ac": "F1NS09-1", "url": "https://www.uniprot.org/uniprotkb/F1NS09/entry#F1NS09-1", "sequence": { "sequence": "MELSCSVGGSTAAPPGPGPPGPIAAPSVPPPMEGEDYESLPSGASLGTHMLAGAVAGIMEHSVMYPVDSVKTRMQSLQPDPKAQYRSVYEALKKMVLTEGFWRPLRGINVTMLGAGPAHAMYFACYEKMKKSLSDTIQHGGNSHLANGIAGSVATLLHDAVMNPAEVVKQRMQMFNSPYKSVWQCVRTVQKTEGFGAFYRSYTTQLTMNVPFQAIHFITYEFMQERVNPHREYHPLSHVCSGAVAGAVAAAATTPLDVCKTLLNTQENTALSSLNITGHLSGMANAFRTVYQLGGIAGYFRGVQARVIYQIPSTAIAWSVYEFFKYFLTKHKLEKRTSL", "length": 339, "header": "tr|F1NS09-1|F1NS09_CHICK Isoform 1 of Mitoferrin-1 OS=Gallus gallus OX=9031 GN=SLC25A37 PE=3 SV=4 CANONICAL=F1NS09-1" }, "locus": { "chromosome": "22", "start_pos": 1242745, "end_pos": 1233914, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048866.1", "url": "https://www.ensembl.org/id/ENSGALT00010048866.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028885.1", "url": "https://www.ensembl.org/id/ENSGALP00010028885.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:419530", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419530", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "E1B7M3-1", "protein_name": "Mitoferrin-1", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MELRRGGVGSQARARRMDGDSRDGGGGCKDAGSEDYENLPTSASLSTHMTAGAMAGILEHSVMYPVDSVKTRMQSLNPDPKAHYTSVYGALKKIIRTEGFWRPLRGLNVMMMGAGPAHAMYFACYENMKRTLNAVFHHQGNSHLANGIAGSMATLLHDAVMNPAEVVKQRMQMYNSPHRSALSCIRTVWGTEGLGAFYRSYTTQLTMNIPFQSIHFITYEFLQEQINPYRGYNPQSHIISGGLAGALAAAATTPLDVCKTLLNTQENMALSLANISGRLSGMANAFRTVYQLNGLPGYFKGVQARVIYQMPSTAISWSVYEFFKYFLTKHKLENRTPY", "length": 338 }, "evidence": [ { "id": "F1NS09", "url": "https://omabrowser.org/oma/group/F1NS09/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P23500-1", "protein_name": "Mitochondrial RNA-splicing protein MRS4", "gene_name": "MRS4", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MNTSELSIAEEIDYEALPSHAPLHSQLLAGAFAGIMEHSLMFPIDALKTRVQAAGLNKAASTGMISQISKISTMEGSMALWKGVQSVILGAGPAHAVYFGTYEFCKARLISPEDMQTHQPMKTALSGTIATIAADALMNPFDTVKQRLQLDTNLRVWNVTKQIYQNEGFAAFYYSYPTTLAMNIPFAAFNFMIYESASKFFNPQNSYNPLIHCLCGGISGATCAALTTPLDCIKTVLQVRGSETVSIEIMKDANTFGRASRAILEVHGWKGFWRGLKPRIVANIPATAISWTAYECAKHFLMKN", "length": 304 }, "evidence": [ { "id": "F1NS09", "url": "https://omabrowser.org/oma/group/F1NS09/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q287T7-1", "protein_name": "Mitoferrin-1", "gene_name": "slc25a37", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MELRTDAVLASLEMSEPVKNDEDYESLPAHASLGTHMTAGAVAGILEHTVMYPVDSVKTRMQSLQPDPKAQYRSVYGALKRIVRTEGLLRPLRGLNITVLGAGPAHALYFACYERIKRSLSDVIQNGGNSHIANGVAGSVATVLHDAVMNPAEVVKQRMQMYNSPYRSLYDCVLMVSRKEGLAAFYRSYSTQLTMNIPFQAVHFITYEFMQEHFNPHRQYRPETHIISGAAAGAVSAAVTTPLDVCKTLLNTQENVALSSAHVSGHLSGMVNALRTVYRLGGVPAFFKGIQARVIYQMPSTAIAWSVYEFFKYFLTQHESHVQEVSHKTSPT", "length": 332 }, "evidence": [ { "id": "F1NS09", "url": "https://omabrowser.org/oma/group/F1NS09/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q66H23-1", "protein_name": "Mitoferrin-1", "gene_name": "Slc25a37", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MELRRGGVGSQAAGRRMDGDCRDGGCGSKDAGSEDYENLPTSASVSTHMTAGAMAGILEHSIMYPVDSVKTRMQSLNPDPKARYTSIYGALKRIMHTEGFWRPLRGLNVMMMGAGPAHAMYFACYENMKRTLNDVFSHQGNSHLANGIAGSMATLLHDAVMNPAEVVKQRLQMYNSQHQSALSCIRTVWRTEGLGAFYRSYTTQLTMNIPFQSIHFITYEFLQEQVNPRRDYNPQSHIISGGLAGALAAAATTPLDVCKTLLNTQENMALSLANVSGRLSGMANAFRTVYQLNGLAGYFKGIQARVIYQMPSTAISWSVYEFFKYFLTKRQLENRTLY", "length": 338 }, "evidence": [ { "id": "F1NS09", "url": "https://omabrowser.org/oma/group/F1NS09/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q920G8-1", "protein_name": "Mitoferrin-1", "gene_name": "Slc25a37", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MELRRGGVGNQAAGRRMDGDCRDGGCGSKDAGSEDYENLPTSASVSTHMTAGAMAGILEHSIMYPVDSVKTRMQSLNPDPKARYTSIYGALKRIMHTEGFWRPLRGLNVMMMGAGPAHAMYFACYENMKRTLNDVFSHQGNSHLANGVAGSMATLLHDAVMNPAEVVKQRLQMYNSQHQSAFSCIRTVWRTEGLGAFYRSYTTQLTMNIPFQSIHFITYEFLQEQVNPRRDYNPQSHIISGGLAGALAAAATTPLDVCKTLLNTQENMALSLANVSGRLSGMANAFRTVYQLNGLAGYFKGIQARVIYQMPSTAISWSVYEFFKYILTKRQLENRTLY", "length": 338 }, "evidence": [ { "id": "F1NS09", "url": "https://omabrowser.org/oma/group/F1NS09/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9NYZ2-1", "protein_name": "Mitoferrin-1", "gene_name": "SLC25A37", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MELRSGSVGSQAVARRMDGDSRDGGGGKDATGSEDYENLPTSASVSTHMTAGAMAGILEHSVMYPVDSVKTRMQSLSPDPKAQYTSIYGALKKIMRTEGFWRPLRGVNVMIMGAGPAHAMYFACYENMKRTLNDVFHHQGNSHLANGIAGSMATLLHDAVMNPAEVVKQRLQMYNSQHRSAISCIRTVWRTEGLGAFYRSYTTQLTMNIPFQSIHFITYEFLQEQVNPHRTYNPQSHIISGGLAGALAAAATTPLDVCKTLLNTQENVALSLANISGRLSGMANAFRTVYQLNGLAGYFKGIQARVIYQMPSTAISWSVYEFFKYFLTKRQLENRAPY", "length": 338 }, "evidence": [ { "id": "F1NS09", "url": "https://omabrowser.org/oma/group/F1NS09/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "F1NS09", "url": "https://www.uniprot.org/uniprotkb/F1NS09" } ], "pmid": "" }, { "name": "mitochondrial membrane", "id": "GO:0031966", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031966", "evidence": [ { "database": "UniProtKB", "id": "F1NS09", "url": "https://www.uniprot.org/uniprotkb/F1NS09" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "positive regulation of hemoglobin biosynthetic process", "id": "GO:0046985", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046985", "evidence": [ { "database": "UniProtKB", "id": "F1NS09", "url": "https://www.uniprot.org/uniprotkb/F1NS09" } ], "pmid": "" }, { "name": "iron import into the mitochondrion", "id": "GO:0048250", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048250", "evidence": [ { "database": "UniProtKB", "id": "F1NS09", "url": "https://www.uniprot.org/uniprotkb/F1NS09" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "ferrous iron transmembrane transporter activity", "id": "GO:0015093", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015093", "evidence": [ { "database": "UniProtKB", "id": "F1NS09", "url": "https://www.uniprot.org/uniprotkb/F1NS09" } ], "pmid": "" }, { "name": "iron ion transmembrane transporter activity", "id": "GO:0005381", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005381", "evidence": [ { "database": "UniProtKB", "id": "F1NS09", "url": "https://www.uniprot.org/uniprotkb/F1NS09" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 109, "end_pos": 111, "annotation": "n_glycosylation_sequon" }, { "start_pos": 275, "end_pos": 277, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "28486", "name": "", "equation": "Fe(2+)(in) = Fe(2+)(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "28486", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/28486" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1NS09-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 339, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1NS09-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1NS09" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 109, "end_pos": 111 }, { "start_pos": 275, "end_pos": 277 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 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"field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1NS14-1", "uniprot_ac": "F1NS14", "uniprot_id": "F1NS14_CHICK", "mass": { "chemical_mass": 48580.0, "monoisotopic_mass": 48580.0 }, "refseq": {}, "gene_names": [ { "name": "CRHR1", "type": "recommended", "evidence": [ { "id": "F1NS14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NS14" } ] } ], "protein_names": [ { "name": "Corticotropin-releasing factor receptor 1", "type": "recommended", "evidence": [ { "id": "F1NS14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NS14/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NS14", "url": "https://www.uniprot.org/uniprotkb/F1NS14" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CRHR1", "url": "https://www.uniprot.org/uniprotkb/F1NS14", "locus": { "chromosome": "27", "start_pos": 1906671, "end_pos": 1880802, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010022705", "url": "https://www.ensembl.org/id/ENSGALG00010022705" } ] } } ], "crossref": [ { "id": "F1NS14", "url": "https://alphafold.ebi.ac.uk/entry/F1NS14", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000000371", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000000371", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd15445", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15445", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "374218", "url": "https://www.ncbi.nlm.nih.gov/gene/374218", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000832", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000832", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001879", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001879", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003051", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003051", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003052", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003052", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017981", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017981", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017983", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017983", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036445", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036445", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050332", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050332", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:374218", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:374218", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PQCNALV", "url": "https://omabrowser.org/oma/group/PQCNALV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZPJ5", "url": "https://www.orthodb.org/?gene=A0A8V0ZPJ5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NS14", "url": "https://www.orthodb.org/?gene=F1NS14", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45620", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45620", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45620:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45620:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00002", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00002", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02793", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02793", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-373080", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-373080", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-418555", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-418555", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_989652", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989652", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZPJ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPJ5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZPJ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPJ5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NS14", "url": "https://www.uniprot.org/uniprotkb/F1NS14", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NS14-1", "url": "https://www.uniprot.org/uniprotkb/F1NS14-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVPGPRPALLLLLFLLQAFLLWDSPVAASIQEQYCESLLPTTNHTGPQCNASVDLIGTCWPRSAVGQLVARPCPEYFYGVRYNTTNNGYRECLANGSWAARVNYSQCQEILSEEKRSKLHYHIAVIINYLGHCVSLGALLVAFVLFMRLRSIRCLRNIIHWNLITAFILRNATWFVVQLTMNPEVHESNVVWCRLVTAAYNYFHVTNFFWMFGEGCYLHTAIVLTYSTDKLRKWMFICIGWCIPFPIIVAWAIGKLYYDNEKCWFGKRAGVYTDYIYQGPMILVLLINFIFLFNIVRILMTKLRASTTSETIQYRKAVKATLVLLPLLGITYMLFFVNPGEDEISRIVFIYFNSFLESFQGFFVSVFYCFLNSEVRSAVRKRWHRWQDKHSIRARVARAMSIPTSPTRVSFHSIKQSSAV", "length": 420, "header": "tr|F1NS14-1|F1NS14_CHICK Isoform 1 of Corticotropin-releasing factor receptor 1 OS=Gallus gallus OX=9031 GN=CRHR1 PE=3 SV=1 CANONICAL=F1NS14-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZPJ5-1", "url": "https://www.uniprot.org/uniprotkb/F1NS14/entry#A0A8V0ZPJ5-1", "sequence": { "sequence": "MVPGPRPALLLLLFLLQAFLLWDSPVAASIQEQYCESLLPTTNHTGPQCNASVDLIGTCWPRSAVGQLVARPCPEYFYGVRYNTTNNGYRECLANGSWAARVNYSQCQEILSEEKRSKLHYHIAVIINYLGHCVSLGALLVAFVLFMRLRSIRCLRNIIHWNLITAFILRNATWFVVQLTMNPEVHESNVVWCRLVTAAYNYFHVTNFFWMFGEGCYLHTAIVLTYSTDKLRKWMFICIGWCIPFPIIVAWAIGKLYYDNEKCWFGKRAGVYTDYIYQGPMILVLLINFIFLFNIVRILMTKLRASTTSETIQYRKAVKATLVLLPLLGITYMLFFVNPGEDEISRIVFIYFNSFLESFQVRSAVRKRWHRWQDKHSIRARVARAMSIPTSPTRVSFHSIKQSSAV", "length": 406, "header": "tr|A0A8V0ZPJ5-1|A0A8V0ZPJ5_CHICK Computationally mapped isoform of Corticotropin-releasing factor receptor 1 OS=Gallus gallus OX=9031 GN=CRHR1 PE=3 SV=1 CANONICAL=F1NS14-1" }, "locus": { "chromosome": "27", "start_pos": 1904720, "end_pos": 1880987, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010055218.1", "url": "https://www.ensembl.org/id/ENSGALT00010055218.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033405.1", "url": "https://www.ensembl.org/id/ENSGALP00010033405.1" } ] } }, { "isoform_ac": "F1NS14-1", "url": "https://www.uniprot.org/uniprotkb/F1NS14/entry#F1NS14-1", "sequence": { "sequence": "MVPGPRPALLLLLFLLQAFLLWDSPVAASIQEQYCESLLPTTNHTGPQCNASVDLIGTCWPRSAVGQLVARPCPEYFYGVRYNTTNNGYRECLANGSWAARVNYSQCQEILSEEKRSKLHYHIAVIINYLGHCVSLGALLVAFVLFMRLRSIRCLRNIIHWNLITAFILRNATWFVVQLTMNPEVHESNVVWCRLVTAAYNYFHVTNFFWMFGEGCYLHTAIVLTYSTDKLRKWMFICIGWCIPFPIIVAWAIGKLYYDNEKCWFGKRAGVYTDYIYQGPMILVLLINFIFLFNIVRILMTKLRASTTSETIQYRKAVKATLVLLPLLGITYMLFFVNPGEDEISRIVFIYFNSFLESFQGFFVSVFYCFLNSEVRSAVRKRWHRWQDKHSIRARVARAMSIPTSPTRVSFHSIKQSSAV", "length": 420, "header": "tr|F1NS14-1|F1NS14_CHICK Isoform 1 of Corticotropin-releasing factor receptor 1 OS=Gallus gallus OX=9031 GN=CRHR1 PE=3 SV=1 CANONICAL=F1NS14-1" }, "locus": { "chromosome": "27", "start_pos": 1904720, "end_pos": 1880987, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010055228.1", "url": "https://www.ensembl.org/id/ENSGALT00010055228.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033414.1", "url": "https://www.ensembl.org/id/ENSGALP00010033414.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:374218", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:374218", "resource": "KEGG Pathway" }, { "id": "R-GGA-373080", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-373080", "resource": "Reactome", "description": "Class B/2 (Secretin family receptors)" }, { "id": "R-GGA-418555", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-418555", "resource": "Reactome", "description": "G alpha (s) signalling events" } ], "orthologs": [ { "uniprot_canonical_ac": "F1RRS6-1", "protein_name": "Corticotropin-releasing factor receptor 1", "gene_name": "CRHR1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGRRPQLRLVKALLLLGLNSISASLQDQHCESLSLASNVSGLQCNASVDLIGTCWPQSPAGQLVVRPCPAYFYGVRYNTTNNGYRECLANGTWAARVNYSECHEILSEEKKSKVHYHVAVIINYLGHCVSLVALLVAFVLFLRLRSIRCLRNIIHWNLISAFILRNATWFVVQLTMSPEVHQSNVGWCRLVTAAYNYFHVTNFFWMFGEGCYLHTAIVLTYSTDRLRKWMFICIGWGVPFPIIVAWAIGKLYYDNEKCWFGKRPGVYTDYIYQGPMILVLLINFIFLFNIVRILMTKLRASTTSETIQYRKAVKATLVLLPLLGITYMLFFVNPGEDEVSRVVFIYFNSFLESFQGFFVSVFYCFLNSEVRSAIRKRWHRWQDKHSIRARVARAMSIPTSPTRVSFHSIKQSTAV", "length": 415 }, "evidence": [ { "id": "F1NS14", "url": "https://omabrowser.org/oma/group/F1NS14/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P35347-1", "protein_name": "Corticotropin-releasing hormone receptor 1", "gene_name": "Crhr1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGQRPQLRLVKALLLLGLNPVSTSLQDQQCESLSLASNVSGLQCNASVDLIGTCWPRSPAGQLVVRPCPAFFYGVRYNTTNNGYRECLANGSWAARVNYSECQEILNEEKKSKVHYHIAVIINYLGHCISLVALLVAFVLFLRLRSIRCLRNIIHWNLISAFILRNATWFVVQLTVSPEVHQSNVAWCRLVTAAYNYFHVTNFFWMFGEGCYLHTAIVLTYSTDRLRKWMFVCIGWGVPFPIIVAWAIGKLYYDNEKCWFGKRPGVYTDYIYQGPMILVLLINFIFLFNIVRILMTKLRASTTSETIQYRKAVKATLVLLPLLGITYMLFFVNPGEDEVSRVVFIYFNSFLESFQGFFVSVFYCFLNSEVRSAIRKRWRRWQDKHSIRARVARAMSIPTSPTRVSFHSIKQSTAV", "length": 415 }, "evidence": [ { "id": "F1NS14", "url": "https://omabrowser.org/oma/group/F1NS14/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P35353-1", "protein_name": "Corticotropin-releasing hormone receptor 1", "gene_name": "Crhr1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGRRPQLRLVKALLLLGLNPVSTSLQDQRCENLSLTSNVSGLQCNASVDLIGTCWPRSPAGQLVVRPCPAFFYGVRYNTTNNGYRECLANGSWAARVNYSECQEILNEEKKSKVHYHVAVIINYLGHCISLVALLVAFVLFLRLRSIRCLRNIIHWNLISAFILRNATWFVVQLTVSPEVHQSNVAWCRLVTAAYNYFHVTNFFWMFGEGCYLHTAIVLTYSTDRLRKWMFVCIGWGVPFPIIVAWAIGKLHYDNEKCWFGKRPGVYTDYIYQGPMILVLLINFIFLFNIVRILMTKLRASTTSETIQYRKAVKATLVLLPLLGITYMLFFVNPGEDEVSRVVFIYFNSFLESFQGFFVSVFYCFLNSEVRSAIRKRWRRWQDKHSIRARVARAMSIPTSPTRVSFHSIKQSTAV", "length": 415 }, "evidence": [ { "id": "F1NS14", "url": "https://omabrowser.org/oma/group/F1NS14/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "X1WHD4-1", "protein_name": "Corticotropin-releasing factor receptor 1", "gene_name": "crhr1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSRILHPQVLTIWITLISRATADLTCDALLLLSTNLTARTLILWNQTSSPTTNSTGLFCNTSIDGIGTCWPRSSAGEVVSRPCPESFLGVRYNTTNNVYRECLANGTWAKKGNYSQCQEILNEEKKSKLHYHIAVIINYLGHCISLGALLVAFILFMRLRSIRCLRNIIHWNLITAFILRNATWFVVQLTMNPEVHESNVIWCRLVTAAYNYFHVTNFFWMFGEGCYLHTAIVLTYSTDKLRKWMFICIGWCIPFPIIVAWAIGKLYYDNEKCWFGKRAGIYTDYIYQGPMILVLLINFIFLFNIVRILMTKLRASTTSETIQYRKAVKATLVLLPLLGITYMLFFVNPGEDEISQIVFIYFNSFLESFQGFFVSVFYCFLNSEVRSAVRKRWHRWQDKHSIRARVARAMSIPTSPTRVSFHSIKQSSAV", "length": 430 }, "evidence": [ { "id": "F1NS14", "url": "https://omabrowser.org/oma/group/F1NS14/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F1NS14", "url": "https://www.uniprot.org/uniprotkb/F1NS14" } ], "pmid": "" }, { "name": "neuron projection", "id": "GO:0043005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043005", "evidence": [ { "database": "UniProtKB", "id": "F1NS14", "url": "https://www.uniprot.org/uniprotkb/F1NS14" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "cell surface receptor signaling pathway", "id": "GO:0007166", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007166", "evidence": [ { "database": "UniProtKB", "id": "F1NS14", "url": "https://www.uniprot.org/uniprotkb/F1NS14" } ], "pmid": "" }, { "name": "adenylate cyclase-activating G protein-coupled receptor signaling pathway", "id": "GO:0007189", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007189", "evidence": [ { "database": "UniProtKB", "id": "F1NS14", "url": "https://www.uniprot.org/uniprotkb/F1NS14" } ], "pmid": "" }, { "name": "regulation of transport", "id": "GO:0051049", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051049", "evidence": [ { "database": "UniProtKB", "id": "F1NS14", "url": "https://www.uniprot.org/uniprotkb/F1NS14" } ], "pmid": "" }, { "name": "cellular response to hormone stimulus", "id": "GO:0032870", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032870", "evidence": [ { "database": "UniProtKB", "id": "F1NS14", "url": "https://www.uniprot.org/uniprotkb/F1NS14" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "G protein-coupled peptide receptor activity", "id": "GO:0008528", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008528", "evidence": [ { "database": "UniProtKB", "id": "F1NS14", "url": "https://www.uniprot.org/uniprotkb/F1NS14" } ], "pmid": "" }, { "name": "corticotrophin-releasing factor receptor activity", "id": "GO:0015056", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015056", "evidence": [ { "database": "UniProtKB", "id": "F1NS14", "url": "https://www.uniprot.org/uniprotkb/F1NS14" } ], "pmid": "" }, { "name": "corticotropin-releasing hormone binding", "id": "GO:0051424", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051424", "evidence": [ 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"https://www.ensembl.org/id/ENSGALP00010038337.1" } ] } }, { "isoform_ac": "F1NS84-1", "url": "https://www.uniprot.org/uniprotkb/F1NS84/entry#F1NS84-1", "sequence": { "sequence": "MEHQLLCCEVETIRRAYLDANLLNDRVLQTMLKAEETCSPSVSYFKCVQKEILPYMRKIVATWMLEVCEEQKCEEEVFPLAMNYLDRFLSFEPLKKSRLQLLGATCMFVASKMKETIPLTAEKLCIYTDNSIRPDELLQMELLLVNKLKWNLAAMTPHDFIEHFLTKMPLAEDTKQIIRKHAQTFVALCATDVKFISNPPSMIAAGSVVAAVQGLHLGNTNTFLSYQCLTHFLSQVIKCDPDCLRACQEQIESLLESSLRQAQQHNVSSETKTVEDEADLSCTPTDVRDVNI", "length": 292, "header": "tr|F1NS84-1|F1NS84_CHICK Isoform 1 of Cyclin D1 OS=Gallus gallus OX=9031 GN=CCND1 PE=3 SV=2 CANONICAL=F1NS84-1" }, "locus": { "chromosome": "5", "start_pos": 17094358, "end_pos": 17081516, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010062057.1", "url": "https://www.ensembl.org/id/ENSGALT00010062057.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038338.1", "url": "https://www.ensembl.org/id/ENSGALP00010038338.1" } ] } } ], "glycosylation": [], 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"https://www.reactome.org/PathwayBrowser/#R-GGA-8951936", "resource": "Reactome", "description": "RUNX3 regulates p14-ARF" }, { "id": "R-GGA-9754119", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9754119", "resource": "Reactome", "description": "Drug-mediated inhibition of CDK4/CDK6 activity" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287BRJ4-1", "protein_name": "Cyclin D1", "gene_name": "CCND1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAHQLLCCEMETIRRAYPDANLLNDRVLRAMLKAEETCSPSVSYFKCVQKEILPSMRKIVATWMLEVCEEQKCEEEVFPLAMNYLDRFLSLEPVKKSRLQLLGATCMFVASKMKETIPLTAEKLCIYTDNSIRPDELLQMELLLVNKLKWNLAAMTPHDFIEHFLSKMPVAEENKQIIRKHAQTFVALCATDVKFISNPPSMVAAGSVVAAVQGLHLGSSNSFLSYHRLTRFLSRVIRCDPDCLRACQEQIEALLESSLRQAQQQTLDPKAAEEEEEEEEVDLACTPTDVRDVNI", "length": 295 }, "evidence": [ { "id": "F1NS84", "url": "https://omabrowser.org/oma/group/F1NS84/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P24385-1", "protein_name": "G1/S-specific cyclin-D1", "gene_name": "CCND1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEHQLLCCEVETIRRAYPDANLLNDRVLRAMLKAEETCAPSVSYFKCVQKEVLPSMRKIVATWMLEVCEEQKCEEEVFPLAMNYLDRFLSLEPVKKSRLQLLGATCMFVASKMKETIPLTAEKLCIYTDNSIRPEELLQMELLLVNKLKWNLAAMTPHDFIEHFLSKMPEAEENKQIIRKHAQTFVALCATDVKFISNPPSMVAAGSVVAAVQGLNLRSPNNFLSYYRLTRFLSRVIKCDPDCLRACQEQIEALLESSLRQAQQNMDPKAAEEEEEEEEEVDLACTPTDVRDVDI", "length": 295 }, "evidence": [ { "id": "F1NS84", "url": "https://omabrowser.org/oma/group/F1NS84/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P25322-1", "protein_name": "G1/S-specific cyclin-D1", "gene_name": "Ccnd1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEHQLLCCEVETIRRAYPDTNLLNDRVLRAMLKTEETCAPSVSYFKCVQKEIVPSMRKIVATWMLEVCEEQKCEEEVFPLAMNYLDRFLSLEPLKKSRLQLLGATCMFVASKMKETIPLTAEKLCIYTDNSIRPEELLQMELLLVNKLKWNLAAMTPHDFIEHFLSKMPEADENKQTIRKHAQTFVALCATDVKFISNPPSMVAAGSVVAAMQGLNLGSPNNFLSCYRTTHFLSRVIKCDPDCLRACQEQIEALLESSLRQAQQNVDPKATEEEGEVEEEAGLACTPTDVRDVDI", "length": 295 }, "evidence": [ { "id": "F1NS84", "url": "https://omabrowser.org/oma/group/F1NS84/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q2KI22-1", "protein_name": "G1/S-specific cyclin-D1", "gene_name": "CCND1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAHQLLCCEMETIRRAYPDANLLNDRVLRAMLKAEETCAPSVSYFKCVQKEILPSMRKIVATWMLEVCEEQKCEEEVFPLAMNYLDRFLSLEPVKKSRLQLLGATCMFVASKMKETIPLTAEKLCIYTDNSIRPDELLHMELVLVNKLKWNLAAMTPHDFIEHFLSKMPVAEENKQIIRKHAQTFVALCATDVKFISNPPSMVAAGSVAAAAQGLHLGSANGFLSYHRLTRFLSKVIRCDPDCLRACQEQIEALLESSLRQAQQQNLDPKAAEEEEEEEEVDLACTPTDVRDVNI", "length": 295 }, "evidence": [ { "id": "F1NS84", "url": "https://omabrowser.org/oma/group/F1NS84/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q90459-1", "protein_name": "G1/S-specific cyclin-D1", "gene_name": "ccnd1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEHQLFCCEVDTIRRAYQDSNLLNDRVLQTMLKAEENYLPSPNYFKCVQKEIVPKMRKIVATWMLEVCEEQKCEEEVFPLAMNYLDRFLSVEPTKKTRLQLLGATCMFLASKMKETVPLTAEKLCIYTDNSVRPGELLQMELLALNKLKWDLASVTPHDFIEHFLAKLPIHQSSKQILRKHAQTFVALCATDVNFIASPPSMIAAGSVAAAVQGLYLKSTDSCLSSQNLTNFLSQVIRSDPDCLRSCQEQIESLLESSLRQAQQHISTETKRVEEDVDLSCTPTDVRDINI", "length": 291 }, "evidence": [ { "id": "F1NS84", "url": "https://omabrowser.org/oma/group/F1NS84/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 9, "go_terms": [ { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "F1NS84", "url": "https://www.uniprot.org/uniprotkb/F1NS84" } ], "pmid": "" }, { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "F1NS84", "url": "https://www.uniprot.org/uniprotkb/F1NS84" } ], "pmid": "" }, { "name": "positive regulation of G2/M transition of mitotic cell cycle", "id": "GO:0010971", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010971", "evidence": [ { "database": "UniProtKB", "id": "F1NS84", "url": "https://www.uniprot.org/uniprotkb/F1NS84" } ], "pmid": "" }, { "name": "G1/S transition of mitotic cell cycle", "id": "GO:0000082", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000082", "evidence": [ { "database": "UniProtKB", "id": "F1NS84", "url": "https://www.uniprot.org/uniprotkb/F1NS84" } ], "pmid": "" }, { "name": "positive regulation of G1/S transition of mitotic cell cycle", "id": "GO:1900087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1900087", "evidence": [ { "database": "UniProtKB", "id": "F1NS84", "url": "https://www.uniprot.org/uniprotkb/F1NS84" } ], "pmid": "" }, { "name": "response to xenobiotic stimulus", "id": "GO:0009410", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009410", "evidence": [ { "database": "UniProtKB", "id": "F1NS84", "url": "https://www.uniprot.org/uniprotkb/F1NS84" } ], "pmid": "" }, { "name": "response to UV-A", "id": "GO:0070141", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070141", "evidence": [ { "database": "UniProtKB", "id": "F1NS84", "url": "https://www.uniprot.org/uniprotkb/F1NS84" } ], "pmid": "" }, { "name": "mitotic G1 DNA damage checkpoint signaling", "id": "GO:0031571", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031571", "evidence": [ { "database": "UniProtKB", "id": "F1NS84", "url": "https://www.uniprot.org/uniprotkb/F1NS84" } ], "pmid": "" }, { "name": "response to leptin", "id": "GO:0044321", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044321", "evidence": [ { "database": "UniProtKB", "id": "F1NS84", "url": "https://www.uniprot.org/uniprotkb/F1NS84" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 7, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1NS84", "url": "https://www.uniprot.org/uniprotkb/F1NS84" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1NS84", "url": "https://www.uniprot.org/uniprotkb/F1NS84" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "F1NS84", "url": "https://www.uniprot.org/uniprotkb/F1NS84" } ], "pmid": "" }, { "name": "bicellular tight junction", "id": "GO:0005923", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005923", "evidence": [ { "database": "UniProtKB", "id": "F1NS84", "url": "https://www.uniprot.org/uniprotkb/F1NS84" } ], "pmid": "" }, { "name": "transcription repressor complex", "id": "GO:0017053", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017053", "evidence": [ { "database": "UniProtKB", "id": "F1NS84", "url": "https://www.uniprot.org/uniprotkb/F1NS84" } ], "pmid": "" }, { "name": "microtubule organizing center", "id": "GO:0005815", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005815", "evidence": [ { "database": "UniProtKB", "id": "F1NS84", "url": "https://www.uniprot.org/uniprotkb/F1NS84" } ], "pmid": "" }, { "name": "cyclin-dependent protein kinase holoenzyme complex", "id": "GO:0000307", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000307", "evidence": [ { "database": "UniProtKB", "id": "F1NS84", "url": "https://www.uniprot.org/uniprotkb/F1NS84" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 7, "go_terms": [ { "name": "protein kinase activity", "id": "GO:0004672", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004672", "evidence": [ { "database": "UniProtKB", "id": "F1NS84", "url": "https://www.uniprot.org/uniprotkb/F1NS84" } ], "pmid": "" }, { "name": "protein kinase binding", "id": "GO:0019901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019901", "evidence": [ { "database": "UniProtKB", "id": "F1NS84", "url": "https://www.uniprot.org/uniprotkb/F1NS84" } ], "pmid": "" }, { "name": "transcription corepressor activity", "id": "GO:0003714", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003714", "evidence": [ { "database": "UniProtKB", "id": "F1NS84", "url": "https://www.uniprot.org/uniprotkb/F1NS84" } ], "pmid": "" }, { "name": "histone deacetylase binding", "id": "GO:0042826", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042826", "evidence": [ { "database": "UniProtKB", "id": "F1NS84", "url": "https://www.uniprot.org/uniprotkb/F1NS84" } ], "pmid": "" }, { "name": "proline-rich region binding", "id": "GO:0070064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070064", "evidence": [ { "database": "UniProtKB", "id": "F1NS84", "url": "https://www.uniprot.org/uniprotkb/F1NS84" } ], "pmid": "" }, { "name": "cyclin-dependent protein serine/threonine kinase regulator activity", "id": "GO:0016538", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016538", "evidence": [ { "database": "UniProtKB", "id": "F1NS84", "url": "https://www.uniprot.org/uniprotkb/F1NS84" } ], "pmid": "" }, { "name": "cyclin-dependent protein serine/threonine kinase activator activity", "id": "GO:0061575", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061575", "evidence": [ { "database": "UniProtKB", "id": "F1NS84", "url": "https://www.uniprot.org/uniprotkb/F1NS84" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 266, "end_pos": 268, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1NS84", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NS84" }, { "id": "SM01332", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM01332" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Cyclin C-terminal", "eco_id": "ECO_0000259", "start_pos": 155, "end_pos": 280, "start_aa": "Met", "end_aa": "Leu", "glycosite_overlap": "" }, { "evidence": [ { "id": "F1NS84", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NS84" }, { "id": "SM00385", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00385" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Cyclin-like", "eco_id": "ECO_0000259", "start_pos": 62, "end_pos": 146, "start_aa": "Thr", "end_aa": "Asn", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 266, "end_pos": 268 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { 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"o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1NSS3-1", "uniprot_ac": "F1NSS3", "uniprot_id": "F1NSS3_CHICK", "mass": { "chemical_mass": 43478.0, "monoisotopic_mass": 43478.0 }, "refseq": { "ac": "XP_419535", "name": "dimethyladenosine transferase 2, mitochondrial", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_419535" }, "gene_names": [ { "name": "TFB2M", "type": "recommended", "evidence": [ { "id": "F1NSS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NSS3" } ] }, { "name": "TFB2M", "type": "synonym", "evidence": [ { "id": "XP_419535", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_419535" } ] } ], "protein_names": [ { "name": "rRNA adenine N(6)-methyltransferase", "type": "recommended", "evidence": [ { "id": "F1NSS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NSS3/entry#names_and_taxonomy" } ] }, { "name": "2.1.1.-", "type": "synonym", "evidence": [ { "id": "F1NSS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NSS3/entry#names_and_taxonomy" } ] }, { "name": "dimethyladenosine transferase 2, mitochondrial", "type": "synonym", "evidence": [ { "id": "XP_419535", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_419535" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052534.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Nov 16, 2006 this sequence version replaced XP_419535.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_419535", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_419535" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NSS3", "url": "https://www.uniprot.org/uniprotkb/F1NSS3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TFB2M", "url": "https://www.uniprot.org/uniprotkb/F1NSS3", "locus": { "chromosome": "3", "start_pos": 33620229, "end_pos": 33612074, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010010346", "url": "https://www.ensembl.org/id/ENSGALG00010010346" } ] } } ], "crossref": [ { "id": "F1NSS3", "url": "https://alphafold.ebi.ac.uk/entry/F1NSS3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000010651", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000010651", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "421488", "url": "https://www.ncbi.nlm.nih.gov/gene/421488", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001737", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001737", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020598", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020598", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029063", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029063", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:421488", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:421488", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "IFEVPWT", "url": "https://omabrowser.org/oma/group/IFEVPWT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1NSS3", "url": "https://www.orthodb.org/?gene=F1NSS3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11727", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11727", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11727:SF13", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11727:SF13", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00398", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00398", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-163282", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-163282", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_419535", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_419535", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1NSS3", "url": "https://www.uniprot.org/uniprotkb/F1NSS3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NSS3-1", "url": "https://www.uniprot.org/uniprotkb/F1NSS3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRAGRALPGAAGCGRLLAAGLRPLLGGPGPCWATVRRAAGRWPSPGLRVPQAAEAEQLVLRAGGPWGRFIACPQLARTVQRCLQAGSGPQPVVLECAPGPGVLTRTLLNAGVRVVALESHPAFLSKLQSLENSLDGQLKVIYGDFFRLDPLVTGAVKPPAVCSDKLFEAMGIAAVPWRADVPVKIFGIFPQRKERNTLWRLLFILYECSSIYRYGRVELNIFISEKEYKVLTAKPGELRIYQALSVLWQAGCDIQLLHMEPWSSFLTNMKNGRLAIPKSTRLPNDHLCLVRLTPQQNLFTGGLKPANSATFIFMVKQCLTKPRSKLIDRLNSWSLDNADKLLKALEIPEYVETGNVYPEDYKRLFCALQNSSVFTESWFHDEVLESIRNINL", "length": 392, "header": "tr|F1NSS3-1|F1NSS3_CHICK Isoform 1 of rRNA adenine N(6)-methyltransferase OS=Gallus gallus OX=9031 GN=TFB2M PE=3 SV=4 CANONICAL=F1NSS3-1" }, "isoforms": [ { "isoform_ac": "F1NSS3-1", "url": "https://www.uniprot.org/uniprotkb/F1NSS3/entry#F1NSS3-1", "sequence": { "sequence": "MRAGRALPGAAGCGRLLAAGLRPLLGGPGPCWATVRRAAGRWPSPGLRVPQAAEAEQLVLRAGGPWGRFIACPQLARTVQRCLQAGSGPQPVVLECAPGPGVLTRTLLNAGVRVVALESHPAFLSKLQSLENSLDGQLKVIYGDFFRLDPLVTGAVKPPAVCSDKLFEAMGIAAVPWRADVPVKIFGIFPQRKERNTLWRLLFILYECSSIYRYGRVELNIFISEKEYKVLTAKPGELRIYQALSVLWQAGCDIQLLHMEPWSSFLTNMKNGRLAIPKSTRLPNDHLCLVRLTPQQNLFTGGLKPANSATFIFMVKQCLTKPRSKLIDRLNSWSLDNADKLLKALEIPEYVETGNVYPEDYKRLFCALQNSSVFTESWFHDEVLESIRNINL", "length": 392, "header": "tr|F1NSS3-1|F1NSS3_CHICK Isoform 1 of rRNA adenine N(6)-methyltransferase OS=Gallus gallus OX=9031 GN=TFB2M PE=3 SV=4 CANONICAL=F1NSS3-1" }, "locus": { "chromosome": "3", "start_pos": 33619394, "end_pos": 33612102, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010024742.1", "url": "https://www.ensembl.org/id/ENSGALT00010024742.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010014030.1", "url": "https://www.ensembl.org/id/ENSGALP00010014030.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "gga:421488", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:421488", "resource": "KEGG Pathway" }, { "id": "R-GGA-163282", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-163282", "resource": "Reactome", "description": "Mitochondrial transcription initiation" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2LEF8-1", "protein_name": "rRNA adenine N(6)-methyltransferase", "gene_name": "Tfb2m", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MWGPAMGLPPRLALSVFAGPARSCVLGSRTAARKDWQAKSRRGFSDFYMQPLFDPELEESPFFAPKGRSEPTCYVACKKLAKNLVRNLLGYHNPSRQLLLECNPGPGILTEALLRAGARVIAFESEKTFIPHLKSLRMHLDGLLQVVHSDFFKIDPRHQEVVKPEYNSRIIFKDLGINPVPWSAGVPIKVFGILPTKLERRILWKTLFDLYSCESIYRYGRIELNLFVTEKEFQRLIATPKRPDLYQVLSVLWQVACDIKFIHMEPWSSFSMHNENGSSENSKLGESLKSMKQNLYFIQLTPRRTLFTEHLSPLNYDIFFHMVKHCFGKRSSPIIQHLRSLSTVEPIEILRKVRIKPGETILRMYPHDFKRLFEMIERSEDCVFKWVYDESLEDIVL", "length": 397 }, "evidence": [ { "id": "F1NSS3", "url": "https://omabrowser.org/oma/group/F1NSS3/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "I3L5G3-1", "protein_name": "rRNA adenine N(6)-methyltransferase", "gene_name": "TFB2M", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MWVPWAGLPPRLTLSALTVPGRFCTLRSGAARRKDVPAGHRRALSDFQPKLVPCVGFGKSRVYKHNSEPKRYITNPRVAENLVRILRRKRKSGQLFLECNPGPGFLTRALLESGARVIACESDKAFIPQLEDLGQKLGGKLKVVYCDFFKLDPRGHGALTPPIMTAETLFRNLGIGPNPWSKGAAFKVVGVLPTRNERNTLWKLLHDLYSCTSIYEYGRVEVNMFVTEKECRKIMANPQNPNLYQALSVLCQLACGIKVLHTEPCSSFRTFIQNGQLEKKQHRESEQNLCFIQLSPHRNLFARTLTPFNYDVFFHMVRQCFMKRNAMLVDHLRSLSPVDALHIMNQMRKKHSMKIVDMYPEDFQRLFEIIECSKDGACRWLYDDFMEDTLT", "length": 391 }, "evidence": [ { "id": "F1NSS3", "url": "https://omabrowser.org/oma/group/F1NSS3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q32LD4-1", "protein_name": "Dimethyladenosine transferase 2, mitochondrial", "gene_name": "TFB2M", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MWVPGAGIPSRLTLSAFTRAARFCVLNSGVARWKDVPAENCRGLYDFHTQLKPDVEFGKLSSRLYKSRSETKRYVTSPRVAETVVRVLRGKRKAGQLILECNPGPGVLTRALLESGARVIALESDKNFIPELKSLGNSVNGRLEVIYCDFFKLDPRNHGMVTPPVMTSDMLFQYLGVKAHPWKKGFPLKVVGILPAKTERNTLWKILHDLYSCSSVYKYGRAELNLFISEKECRKLTANPQTPALYQSLSVLGQTACGIKVLCTEPSSLFDTYAIKGELEKQRHRESLEQNLCFVQLTPHRNLFTGTLTPFNYDVFFHMLRQCFMKRNAKLIDHLPSLSPIDAVHILKQIKKKKDVRVVDMYPKDFLRLFETIECSKDDTCKWLYDEFMEDALS", "length": 394 }, "evidence": [ { "id": "F1NSS3", "url": "https://omabrowser.org/oma/group/F1NSS3/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q3TL26-1", "protein_name": "Dimethyladenosine transferase 2, mitochondrial", "gene_name": "Tfb2m", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRGPAMRLPPRIALSALARGPSCILGSGAATRKDWQTRNRRGFSDFNIEPLPDSDLEESSPWTSRNRSEPTRHIACKKAARNLVRDLLEHQNPSRQIILECNPGPGILTGALLKAGARVVAFESEKTFIPHLEPLQRNMDGELQVVHCDFFKMDPRYQEVVRPDVSSQAIFQNLGIKAVPWSAGVPIKVFGILPYKHERRILWKILFDLYSCESIYRYGRVELNMFVSEKEFRKLIATPKRPDLYQVMAVLWQVACDVKFLHMEPWSSFSVHTENGHLEKSKHGESVNLLKQNLYLVRMTPRRTLFTENLSPLNYDIFFHLVKHCFGKRNAPIIRHLRSLSTVDPINILRQIRKNPGDTAARMYPHDFKKLFETIEQSEDSVFKWIYDYCPEDMEF", "length": 396 }, "evidence": [ { "id": "F1NSS3", "url": "https://omabrowser.org/oma/group/F1NSS3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q5U2T7-1", "protein_name": "Dimethyladenosine transferase 2, mitochondrial", "gene_name": "Tfb2m", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRGLAMRLPPRLALSVLAGRGPSCILGSGAATRKDWQERNRRSFSDLYTQPLPDCDFEESSSWTHKSRSEPTRHIACKKSARNLVRDLLEHQNPSHQLILECNPGPGILTGALLKAGARVVAFESEKMFIPHLESLRKNADGELQVVHCDFFKIDPRYQELVRPDVNSHTIFQNLGIKAVPWSAGVPIKVFGILPNKHERRLLWKILFDLYSCESIYRYGRVELNMFISEKEFRKLIATPKRPDLYQVLGVLWQVACEIKFLHMEPWSSFSVHAENGHLEKSKHSESLNLLKQNLYLVRMTPRRTLFTENLSPLNYDMFFHLVKHCFGKRNAPIIHHLRSLSTVDPINILRQIRKRPGDTAAKMYPHDFKRLFETIERSEDSVFKWIYDYCSDDSEL", "length": 397 }, "evidence": [ { "id": "F1NSS3", "url": "https://omabrowser.org/oma/group/F1NSS3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9H5Q4-1", "protein_name": "Dimethyladenosine transferase 2, mitochondrial", "gene_name": "TFB2M", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MWIPVVGLPRRLRLSALAGAGRFCILGSEAATRKHLPARNHCGLSDSSPQLWPEPDFRNPPRKASKASLDFKRYVTDRRLAETLAQIYLGKPSRPPHLLLECNPGPGILTQALLEAGAKVVALESDKTFIPHLESLGKNLDGKLRVIHCDFFKLDPRSGGVIKPPAMSSRGLFKNLGIEAVPWTADIPLKVVGMFPSRGEKRALWKLAYDLYSCTSIYKFGRIEVNMFIGEKEFQKLMADPGNPDLYHVLSVIWQLACEIKVLHMEPWSSFDIYTRKGPLENPKRRELLDQLQQKLYLIQMIPRQNLFTKNLTPMNYNIFFHLLKHCFGRRSATVIDHLRSLTPLDARDILMQIGKQEDEKVVNMHPQDFKTLFETIERSKDCAYKWLYDETLEDR", "length": 396 }, "evidence": [ { "id": "F1NSS3", "url": "https://omabrowser.org/oma/group/F1NSS3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "rRNA methylation", "id": "GO:0031167", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031167", "evidence": [ { "database": "UniProtKB", "id": "F1NSS3", "url": "https://www.uniprot.org/uniprotkb/F1NSS3" } ], "pmid": "" }, { "name": "transcription initiation at mitochondrial promoter", "id": "GO:0006391", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006391", "evidence": [ { "database": "UniProtKB", "id": "F1NSS3", "url": "https://www.uniprot.org/uniprotkb/F1NSS3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "F1NSS3", "url": "https://www.uniprot.org/uniprotkb/F1NSS3" } ], "pmid": "" }, { "name": "rRNA (adenine-N6,N6-)-dimethyltransferase activity", "id": "GO:0000179", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000179", "evidence": [ { "database": "UniProtKB", "id": "F1NSS3", "url": "https://www.uniprot.org/uniprotkb/F1NSS3" } ], "pmid": "" }, { "name": "mitochondrial transcription factor activity", "id": "GO:0034246", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034246", "evidence": [ { "database": "UniProtKB", "id": "F1NSS3", "url": "https://www.uniprot.org/uniprotkb/F1NSS3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "mitochondrial matrix", "id": "GO:0005759", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005759", "evidence": [ { "database": "UniProtKB", "id": "F1NSS3", "url": "https://www.uniprot.org/uniprotkb/F1NSS3" } ], "pmid": "" }, { "name": "mitochondrial nucleoid", "id": "GO:0042645", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042645", "evidence": [ { "database": "UniProtKB", "id": "F1NSS3", "url": "https://www.uniprot.org/uniprotkb/F1NSS3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 370, "end_pos": 372, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-GGA-163296", "name": "Association of TFAM:mt promoter complex with POLRMT:TFB2M", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "mitochondrial matrix", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1BZ13-1", "F1NSS3-1" ], "evidence": [ { "id": "R-GGA-163296", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-163296" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "E1BZ13", "gene_name": "POLRMT", "activity": [ { "ec_number": "2.7.7.6", "activity": "RNA(n) + a ribonucleoside 5'-triphosphate = RNA(n+1) + diphosphate.", "evidence": [ { "id": "E1BZ13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BZ13" } ] }, { "ec_number": "2.7.7.6", "activity": "", "evidence": [ { "id": "E1BZ13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BZ13" } ] } ] }, { "uniprot_ac": "F1NSS3", "gene_name": "TFB2M", "activity": [ { "ec_number": "2.1.1.-", "activity": "", "evidence": [ { "id": "F1NSS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NSS3" } ] } ] } ], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1NSS3-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 392, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1NSS3-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1NSS3" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1NSS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NSS3" }, { "id": "SM00650", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00650" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ribosomal RNA adenine methylase transferase N-terminal", "eco_id": "ECO_0000259", "start_pos": 78, "end_pos": 273, "start_aa": "Thr", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 370, "end_pos": 372 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1NSS7-1", "uniprot_ac": "F1NSS7", "uniprot_id": "F1NSS7_CHICK", "mass": { "chemical_mass": 40342.0, "monoisotopic_mass": 40342.0 }, "refseq": { "ac": "NP_001026620", "name": "ribosome biogenesis protein BRX1 homolog", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026620" }, "gene_names": [ { "name": "BRIX1", "type": "recommended", "evidence": [ { "id": "F1NSS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NSS7" } ] }, { "name": "BRIX1", "type": "synonym", "evidence": [ { "id": "NP_001026620", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026620" } ] }, { "name": "BXDC2", "type": "synonym", "evidence": [ { "id": "NP_001026620", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026620" } ] } ], "protein_names": [ { "name": "Ribosome biogenesis protein BRX1 homolog", "type": "recommended", "evidence": [ { "id": "F1NSS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NSS7/entry#names_and_taxonomy" } ] }, { "name": "BRX1, biogenesis of ribosomes, homolog", "type": "synonym", "evidence": [ { "id": "NP_001026620", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026620" } ] }, { "name": "Brix domain-containing protein 2", "type": "synonym", "evidence": [ { "id": "F1NSS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NSS7/entry#names_and_taxonomy" } ] }, { "name": "brix domain containing 2", "type": "synonym", "evidence": [ { "id": "NP_001026620", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026620" } ] }, { "name": "ribosome biogenesis protein BRX1 homolog", "type": "synonym", "evidence": [ { "id": "NP_001026620", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026620" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ719625.1, HAEK01015309.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000087.1. On Sep 23, 2021 this sequence version replaced NP_001026620.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001026620", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026620" } ] }, { "annotation": "Required for biogenesis of the 60S ribosomal subunit.", "evidence": [ { "database": "UniProtKB", "id": "F1NSS7", "url": "https://www.uniprot.org/uniprotkb/F1NSS7#function" }, { "database": "UniProtKB", "id": "ARBA00003439", "url": "https://www.uniprot.org/uniprotkb/ARBA00003439#function" }, { "database": "UniProtKB", "id": "A0A8V0YLA7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLA7#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NSS7", "url": "https://www.uniprot.org/uniprotkb/F1NSS7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "BRIX1", "url": "https://www.uniprot.org/uniprotkb/F1NSS7", "locus": { "chromosome": "Z", "start_pos": 11123680, "end_pos": 11119287, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013256", "url": "https://www.ensembl.org/id/ENSGALG00010013256" } ] } } ], "crossref": [ { "id": "F1NSS7", "url": "https://alphafold.ebi.ac.uk/entry/F1NSS7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000003373", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000003373", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "427433", "url": "https://www.ncbi.nlm.nih.gov/gene/427433", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR007109", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007109", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR026532", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026532", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:427433", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427433", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YRHRHLM", "url": "https://omabrowser.org/oma/group/YRHRHLM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YLA7", "url": "https://www.orthodb.org/?gene=A0A8V0YLA7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NSS7", "url": "https://www.orthodb.org/?gene=F1NSS7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13634", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13634", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13634:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13634:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04427", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04427", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001026620", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026620", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YLA7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLA7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLA7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLA7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NSS7", "url": "https://www.uniprot.org/uniprotkb/F1NSS7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NSS7-1", "url": "https://www.uniprot.org/uniprotkb/F1NSS7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAAKRKRELGPAARPKKRAKGAPTGPGPTAKAGPEGAAPEEYSIPAPVSQGKWKNKERVLIFSSRGINFRTRHLMQDLRTLMPHSKADTKMDRKDKLFVINEVCEMKNCNKCIFFEAKKKQDLYMWLSNTPQGPSAKFLVQNIHTLAELKMTGNCLRGSRPLLSFDPTFDKEPHYALLKELFIQIFSTPQYHPKSQPFVDHVFTFTITDKRIWFRNYQIIEEDASLVEIGPRFVLNLIKIFQGSFGGPTLYENPHYQSPNMHRRLIRLSMAAKFREKHQVKEVQKIKKKESKMLIEEDPTEVVFETPAEEKPVEIQLVKPESKAIVKDKRKPRKIQRKKQKKLFRTEG", "length": 349, "header": "tr|F1NSS7-1|F1NSS7_CHICK Isoform 1 of Ribosome biogenesis protein BRX1 homolog OS=Gallus gallus OX=9031 GN=BRIX1 PE=1 SV=1 CANONICAL=F1NSS7-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YLA7-1", "url": "https://www.uniprot.org/uniprotkb/F1NSS7/entry#A0A8V0YLA7-1", "sequence": { "sequence": "MAAAKRKRELGPAARPKKRAKGAPTGPGPTAKAGPEGAAPEEYSIPAPVSQVAVRRIGAELGGSGTRGADGSRCLSLLCDTKMDRKDKLFVINEVCEMKNCNKCIFFEAKKKQDLYMWLSNTPQGPSAKFLVQNIHTLAELKMTGNCLRGSRPLLSFDPTFDKEPHYALLKELFIQIFSTPQYHPKSQPFVDHVFTFTITDKRIWFRNYQIIEEDASLVEIGPRFVLNLIKIFQGSFGGPTLYENPHYQSPNMHRRLIRLSMAAKFREKHQVKEVQKIKKKESKMLIEEDPTEVVFETPAEEKPVEIQLVKPESKAIVKDKRKPRKIQRKKQKKLFRTEG", "length": 340, "header": "tr|A0A8V0YLA7-1|A0A8V0YLA7_CHICK Computationally mapped isoform of Ribosome biogenesis protein BRX1 homolog OS=Gallus gallus OX=9031 GN=BRIX1 PE=1 SV=1 CANONICAL=F1NSS7-1" }, "locus": { "chromosome": "Z", "start_pos": 11122753, "end_pos": 11119348, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031861.1", "url": "https://www.ensembl.org/id/ENSGALT00010031861.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018665.1", "url": "https://www.ensembl.org/id/ENSGALP00010018665.1" } ] } }, { "isoform_ac": "F1NSS7-1", "url": "https://www.uniprot.org/uniprotkb/F1NSS7/entry#F1NSS7-1", "sequence": { "sequence": "MAAAKRKRELGPAARPKKRAKGAPTGPGPTAKAGPEGAAPEEYSIPAPVSQGKWKNKERVLIFSSRGINFRTRHLMQDLRTLMPHSKADTKMDRKDKLFVINEVCEMKNCNKCIFFEAKKKQDLYMWLSNTPQGPSAKFLVQNIHTLAELKMTGNCLRGSRPLLSFDPTFDKEPHYALLKELFIQIFSTPQYHPKSQPFVDHVFTFTITDKRIWFRNYQIIEEDASLVEIGPRFVLNLIKIFQGSFGGPTLYENPHYQSPNMHRRLIRLSMAAKFREKHQVKEVQKIKKKESKMLIEEDPTEVVFETPAEEKPVEIQLVKPESKAIVKDKRKPRKIQRKKQKKLFRTEG", "length": 349, "header": "tr|F1NSS7-1|F1NSS7_CHICK Isoform 1 of Ribosome biogenesis protein BRX1 homolog OS=Gallus gallus OX=9031 GN=BRIX1 PE=1 SV=1 CANONICAL=F1NSS7-1" }, "locus": { "chromosome": "Z", "start_pos": 11122753, "end_pos": 11119348, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031871.1", "url": "https://www.ensembl.org/id/ENSGALT00010031871.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018674.1", "url": "https://www.ensembl.org/id/ENSGALP00010018674.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 30, "start_aa": "Thr", "end_pos": 30, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr30", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:427433", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427433", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "F1SND4-1", "protein_name": "Ribosome biogenesis protein BRX1 homolog", "gene_name": "BRIX1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAGSKMAATKRKRRGGPAGPAKKLKRSEKDAKPPAKSSEVAEEAEEEDRNRIPGPVCKGKWKNKERILIFSSRGINFRTRHLMQDLRMLMPHSKADTKMDRKDKLFVINEVCEMKNCNKCIYFEAKKKQDLYMWLSNSPHGPSAKFLVQNIHTLAELKMTGNCLKGSRPLLSFDPAFDELPHYALLKELLIQIFSTPRYHPKSQPFVDHVFTFTILDNRIWFRNFQIIEEDAALVEIGPRFVLNLIKIFQGSFGGPTLYENPHYQSPNMHRRVIRSITAAKYKEKQQVKDVQKLRKKEPKTILPHDPTADVFVTPAEEKPVEIQWVKPEPKVDLKARKKRIYKRQRKMKQKMSSGNAK", "length": 358 }, "evidence": [ { "id": "F1NSS7", "url": "https://omabrowser.org/oma/group/F1NSS7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3HKF6-1", "protein_name": "Ribosome biogenesis protein BRX1 homolog", "gene_name": "Brix1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MVATKRKRRGGLEVQAKKPKKSRKDSGQPVKQASVEKEVKEEDRDRIPGPVCKGKWKNKERILIFSSRGINFRTRHLMQDLRMLMPHSKADTKMDRKDKLFVINEVCEMKNCNKCIYFEAKKKQDLYMWLSNSPHGPSAKFLVQNIHTLAELKMTGNCLKGSRPLLSFDPAFDELPHYALLKELLIQIFSTPRYHPKSQPFVDHVFTFTILDNRIWFRNFQIIEEDAALVEIGPRFVLNLIKIFQGSFGGPTLYENPHYQSPNMHRRIVRSITAAKYREKQQVKDVQKMRKKEPKTILPHDPTADVFDIPAEEKPVEIQWVKPEPKVDLTARKRRIYKRHRKLQQKMNRGSAK", "length": 353 }, "evidence": [ { "id": "F1NSS7", "url": "https://omabrowser.org/oma/group/F1NSS7/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q08235-1", "protein_name": "Ribosome biogenesis protein BRX1", "gene_name": "BRX1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSSIYKALAGKSKDNKSEKKQGNVKQFMNKQRTLLISSRGVNYRHRHLIQDLSGLLPHSRKEPKLDTKKDLQQLNEIAELYNCNNVLFFEARKHQDLYLWLSKPPNGPTIKFYIQNLHTMDELNFTGNCLKGSRPVLSFDQRFESSPHYQLIKELLVHNFGVPPNARKSKPFIDHVMSFSIVDDKIWVRTYEISHSTKNKEEYEDGEEDISLVEIGPRFVMTVILILEGSFGGPKIYENKQYVSPNVVRAQIKQQAAEEAKSRAEAAVERKIKRRENVLAADPLSNDALFK", "length": 291 }, "evidence": [ { "id": "F1NSS7", "url": "https://omabrowser.org/oma/group/F1NSS7/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q3SZZ0-1", "protein_name": "Ribosome biogenesis protein BRX1 homolog", "gene_name": "BRIX1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAATKRKRRGGLAVQAKKLKRDAKDGKLPAKANDVSEEAAEEEKDRIPGPVCKGKWKNKERILIFSSRGINFRTRHLMQDLRMLMPHSKADTKMDRKDKLFVINEVCEMKNCNKCIYFEAKKKQDLYMWLSNSPHGPSAKFLVQNIHTLAELKMTGNCLKGSRPLLSFDPAFDELPHYALLKELLIQIFSTPRYHPKSQPFVDHVFTFTILDNRIWFRNFQIIEEDAALVEIGPRFVLNLIKIFQGSFGGPTLYENPHYQSPNMHRRVIRSITAAKYREKQQVKDVQKLRKKEPKTILPHDPTADVFVTPAEEKPVEIQWVKPEPKVDLKARKKRIYKRQRKMKQKMSSGNAK", "length": 353 }, "evidence": [ { "id": "F1NSS7", "url": "https://omabrowser.org/oma/group/F1NSS7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q8TDN6-1", "protein_name": "Ribosome biogenesis protein BRX1 homolog", "gene_name": "BRIX1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAATKRKRRGGFAVQAKKPKRNEIDAEPPAKRHATAEEVEEEERDRIPGPVCKGKWKNKERILIFSSRGINFRTRHLMQDLRMLMPHSKADTKMDRKDKLFVINEVCEMKNCNKCIYFEAKKKQDLYMWLSNSPHGPSAKFLVQNIHTLAELKMTGNCLKGSRPLLSFDPAFDELPHYALLKELLIQIFSTPRYHPKSQPFVDHVFTFTILDNRIWFRNFQIIEEDAALVEIGPRFVLNLIKIFQGSFGGPTLYENPHYQSPNMHRRVIRSITAAKYREKQQVKDVQKLRKKEPKTLLPHDPTADVFVTPAEEKPIEIQWVKPEPKVDLKARKKRIYKRQRKMKQRMDSGKTK", "length": 353 }, "evidence": [ { "id": "F1NSS7", "url": "https://omabrowser.org/oma/group/F1NSS7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9DCA5-1", "protein_name": "Ribosome biogenesis protein BRX1 homolog", "gene_name": "Brix1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAATKRKRRGGLEVQAKKPKRSSKDAGQPAKQADVAKEAEEENRDRIPGPVCKGKWKNKERILIFSSRGINFRTRHLMQDLRMLMPHSKADTKMDRKDKLFVINEVCEMKNCNKCIYFEAKKKQDLYMWLSNSPHGPSAKFLVQNIHTLAELKMTGNCLKGSRPLLSFDPAFDDLPHYALLKEFLIQIFSTPRYHPKSQPFVDHVFTFTILDNRIWFRNFQIIEEDAALVEIGPRFVLNLIKIFQGSFGGPTLYENPHYQSPNMHRRVIRSITAAKYRERQQVKDVQKLRKKEPKTILPHDPTADVFVIPAEEKPVEIQWVKPEPKVDLKARKRRIYKRHRKLQQKMSRGSAK", "length": 353 }, "evidence": [ { "id": "F1NSS7", "url": "https://omabrowser.org/oma/group/F1NSS7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9LE16-1", "protein_name": "Ribosome biogenesis protein BRX1 homolog 1", "gene_name": "BRIX1-1", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MGRKRKHSETVTAAPVKDSAPERPQRTLLGWKDKKEDAENSKPAYASVFRNKEKVLVTCSRRINFRYRHLMLNMVSLLPHCKKDSKVEAKSSRGATLNELIELKGSSSCLFFECRKHKDLYMWMVKSPGGPSVKFLVNAVHTMEELKLTGNHLKGSRPLLTFSSNFENDAHWKLLKEMLTQIFGIPEGHRKSKPYHDHVFVFSIVDDHIWFRNYQISVPHNESDKIARGDLDKMTLIEVGPRFCLNPIKIFGGSFGGTTLYENPFYVSPNQIRALEKRNKAGKFAKKIKAKTRRKMHELSNPLEPDEFTDMWNDE", "length": 315 }, "evidence": [ { "id": "F1NSS7", "url": "https://omabrowser.org/oma/group/F1NSS7/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9VZE6-1", "protein_name": "Ribosome biogenesis protein BRX1 homolog", "gene_name": "", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MGRKFQNKKKKAAPQLEIVPLDENPPLPPQRSSDDVVPKKARKEKWVNKQRVLVFSARGISHRDRHLMKDIKTLMPHHRPESKMERSKTLSVVNEMCEMKHCNKAMLFEGRRKRDLYMWISNTSGSTGPSAKFLIENIHTMAELKMTGNCLRGSRPLLSFDSKFDELPHLKLLKELFVQTYSVPNHHPKSQPFVDHVFTFTYLDKRIWFRNFQILSEDGGLSEVGPRYVMNPVKIFDGSFTGKTIWENPDYVSPSKQRQVLKKAAKDKYVNRVEQKVKHEATRPIRAYDGMDNDELFEDDDPVETAKILAAIAKKKKEEAAKQTPKSALTKKIKEKQLQAVKDVIERKKARTIKRVKKV", "length": 359 }, "evidence": [ { "id": "F1NSS7", "url": "https://omabrowser.org/oma/group/F1NSS7/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "F1NSS7", "url": "https://www.uniprot.org/uniprotkb/F1NSS7" } ], "pmid": "" }, { "name": "rRNA binding", "id": "GO:0019843", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019843", "evidence": [ { "database": "UniProtKB", "id": "F1NSS7", "url": "https://www.uniprot.org/uniprotkb/F1NSS7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "F1NSS7", "url": "https://www.uniprot.org/uniprotkb/F1NSS7" } ], "pmid": "" }, { "name": "chromosome", "id": "GO:0005694", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005694", "evidence": [ { "database": "UniProtKB", "id": "F1NSS7", "url": "https://www.uniprot.org/uniprotkb/F1NSS7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "rRNA processing", "id": "GO:0006364", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006364", "evidence": [ { "database": "UniProtKB", "id": "F1NSS7", "url": "https://www.uniprot.org/uniprotkb/F1NSS7" } ], "pmid": "" }, { "name": "ribosomal large subunit assembly", "id": "GO:0000027", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000027", "evidence": [ { "database": "UniProtKB", "id": "F1NSS7", "url": "https://www.uniprot.org/uniprotkb/F1NSS7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1NSS7-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 349, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1NSS7-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1NSS7" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 30 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], 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"type": "synonym", "evidence": [ { "id": "NP_001292146", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001292146" } ] } ], "function": [ { "annotation": "Odorant receptor.", "evidence": [ { "database": "UniProtKB", "id": "F1NT41", "url": "https://www.uniprot.org/uniprotkb/F1NT41#function" }, { "database": "UniProtKB", "id": "ARBA00002936", "url": "https://www.uniprot.org/uniprotkb/ARBA00002936#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NT41", "url": "https://www.uniprot.org/uniprotkb/F1NT41" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "OR1052", "url": "https://www.uniprot.org/uniprotkb/F1NT41", "locus": { "chromosome": "5", "start_pos": 1231307, "end_pos": 1221385, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010023232", "url": "https://www.ensembl.org/id/ENSGALG00010023232" } ] } } ], "crossref": [ { "id": "F1NT41", "url": "https://alphafold.ebi.ac.uk/entry/F1NT41", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15415", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15415", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "428831", "url": "https://www.ncbi.nlm.nih.gov/gene/428831", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:428831", 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"F1NT41-1", "url": "https://www.uniprot.org/uniprotkb/F1NT41-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDGRNESRMTQFILLGLTDGTELQVPLFFIFSVIYTIAVLGNLGMIVLIWTHLQLHTPMYFFLGNLSVIDLCSATVFAPRMLGNFFAQSKAISYSACLSQTFFFVVFITTEVFLLTAMAYDRYVAICSPLLYSTVMTKRVCMQLVVGSYMGGLLNSLTHTCGLLGLPFCGPNVINHYFCDIPPLLQLACSDTHRNETLLLAFSAVIALFTLFVITASYMLILSVILKIQSDDGRKKTFHTCASHLTAITIFFGSLAFSYIQPSSSYSIEQEKVSAVFYTLLVPMLNPLIYSLRNKEVRSSFRRTFRVRELFH", "length": 312, "header": "tr|F1NT41-1|F1NT41_CHICK Isoform 1 of Olfactory receptor OS=Gallus gallus OX=9031 GN=OR1052 PE=3 SV=3 CANONICAL=F1NT41-1" }, "isoforms": [ { "isoform_ac": "F1NT41-1", "url": "https://www.uniprot.org/uniprotkb/F1NT41/entry#F1NT41-1", "sequence": { "sequence": "MDGRNESRMTQFILLGLTDGTELQVPLFFIFSVIYTIAVLGNLGMIVLIWTHLQLHTPMYFFLGNLSVIDLCSATVFAPRMLGNFFAQSKAISYSACLSQTFFFVVFITTEVFLLTAMAYDRYVAICSPLLYSTVMTKRVCMQLVVGSYMGGLLNSLTHTCGLLGLPFCGPNVINHYFCDIPPLLQLACSDTHRNETLLLAFSAVIALFTLFVITASYMLILSVILKIQSDDGRKKTFHTCASHLTAITIFFGSLAFSYIQPSSSYSIEQEKVSAVFYTLLVPMLNPLIYSLRNKEVRSSFRRTFRVRELFH", "length": 312, "header": "tr|F1NT41-1|F1NT41_CHICK Isoform 1 of Olfactory receptor OS=Gallus gallus OX=9031 GN=OR1052 PE=3 SV=3 CANONICAL=F1NT41-1" }, "locus": { "chromosome": "5", "start_pos": 1231307, "end_pos": 1230919, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056648.1", "url": "https://www.ensembl.org/id/ENSGALT00010056648.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034390.1", "url": "https://www.ensembl.org/id/ENSGALP00010034390.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:428831", "name": "", "url": 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"MDAGNHTDVKEFILLGLTENPNWQVPLFLLFSIIYLIILLGNCGMIFLIWLNTHLHTPMYFFLSNLSFCDICYSTVIAPKMLINILSEHKSSKLFSCVLQSFFFMVYATTEVILLSMMAYDRYVAIANPLMYTVIMTFSICINMVLACYLCGLINSLTHTISLLRLYFCGPNIVNHFFCDIPPLLKLSCSDAHINEMLLLVFSGVIAIFTFIIVMVSYIHIIIAILRIRSTEGRLKAFSTCASHLTAVTLFYGSGSFSYIQPSSQYSMEQEKVSAVFYTLVIPMLNPLIYSLRNKDVKEAAIRLTCGWRNTS", "length": 312 }, "evidence": [ { "id": "F1NT41", "url": "https://omabrowser.org/oma/group/F1NT41/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "F1NT41", "url": "https://www.uniprot.org/uniprotkb/F1NT41" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "F1NT41", "url": "https://www.uniprot.org/uniprotkb/F1NT41" } ], "pmid": "" }, { "name": "odorant binding", "id": "GO:0005549", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005549", "evidence": [ { "database": "UniProtKB", "id": "F1NT41", "url": "https://www.uniprot.org/uniprotkb/F1NT41" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F1NT41", "url": "https://www.uniprot.org/uniprotkb/F1NT41" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 195, "end_pos": 197, "annotation": "n_glycosylation_sequon" }, { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" }, { "start_pos": 65, "end_pos": 67, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1NT41-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 312, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1NT41-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1NT41" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1NT41", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NT41" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 41, "end_pos": 290, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 195, "end_pos": 197 }, { "start_pos": 5, "end_pos": 7 }, { "start_pos": 65, "end_pos": 67 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", 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0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1NTA5-1", "uniprot_ac": "F1NTA5", "uniprot_id": "F1NTA5_CHICK", "mass": { "chemical_mass": 40687.0, "monoisotopic_mass": 40687.0 }, "refseq": { "ac": "XP_003641696", "name": "glucose-6-phosphatase 2 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003641696" }, "gene_names": [ { "name": "G6PC2", "type": "recommended", "evidence": [ { "id": "F1NTA5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NTA5" } ] }, { "name": "G6PC2", "type": "synonym", "evidence": [ { "id": "XP_003641696", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003641696" } ] } ], "protein_names": [ { "name": "Glucose-6-phosphatase", "type": "recommended", "evidence": [ { "id": "F1NTA5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NTA5/entry#names_and_taxonomy" } ] }, { "name": "3.1.3.9", "type": "synonym", "evidence": [ { "id": "F1NTA5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NTA5/entry#names_and_taxonomy" } ] }, { "name": "glucose-6-phosphatase 2 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_003641696", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003641696" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052538.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003641696", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003641696" } ] }, { "annotation": "May hydrolyze glucose-6-phosphate to glucose in the endoplasmic reticulum. May be responsible for glucose production through glycogenolysis and gluconeogenesis.", "evidence": [ { "database": "UniProtKB", "id": "F1NTA5", "url": "https://www.uniprot.org/uniprotkb/F1NTA5#function" }, { "database": "UniProtKB", "id": "ARBA00054947", "url": "https://www.uniprot.org/uniprotkb/ARBA00054947#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NTA5", "url": "https://www.uniprot.org/uniprotkb/F1NTA5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "G6PC2", "url": "https://www.uniprot.org/uniprotkb/F1NTA5", "locus": { "chromosome": "7", "start_pos": 18538788, "end_pos": 18550853, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010025362", "url": "https://www.ensembl.org/id/ENSGALG00010025362" } ] } } ], "crossref": [ { "id": "F1NTA5", "url": "https://alphafold.ebi.ac.uk/entry/F1NTA5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000010899", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000010899", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd03381", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03381", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "424171", "url": "https://www.ncbi.nlm.nih.gov/gene/424171", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000326", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000326", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016275", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016275", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036938", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036938", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:424171", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424171", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "EEHLFYV", "url": "https://omabrowser.org/oma/group/EEHLFYV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A4X5", "url": "https://www.orthodb.org/?gene=A0A8V1A4X5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NTA5", "url": "https://www.orthodb.org/?gene=F1NTA5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12591", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12591", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12591:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12591:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01569", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01569", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-70263", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-70263", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_003641696", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003641696", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "16689", "url": "https://www.rhea-db.org/rhea/16689", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V1A4X5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4X5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A4X5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4X5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NTA5", "url": "https://www.uniprot.org/uniprotkb/F1NTA5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NTA5-1", "url": "https://www.uniprot.org/uniprotkb/F1NTA5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDLLHSNGVLIIQHLQRDYRAYQDFLNFMSHVGDPRNIFSFYFPLWFQLNQVVGTKMIWVAVIGDWFNLIFKWILFGHRPYWWVHETMIYPNQSSPCLEQFPITCETGPGSPSGHAMGSSCVWYVMVTAALSYTVRWKEKSAVTLHRLTWSLLWTIFWIIQISVCISRVFIATHFPHQVILGVFAGIVVAEAFEHTPAIQTASLRMYIKTNLFLFIFALGFYLVLKLLDIDLLWSVPKAKKWCANPDWINIDTTPFAGLVRNLGAFFGLGIGINSEMFITSCKGKNSCKLSFRVLCIAASLATLQLYNFVKIPTHTEYLFYILSFCKSAAMPLTVVALVPYCVHTLMRTTDKKCN", "length": 355, "header": "tr|F1NTA5-1|F1NTA5_CHICK Isoform 1 of Glucose-6-phosphatase OS=Gallus gallus OX=9031 GN=G6PC2 PE=3 SV=4 CANONICAL=F1NTA5-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A4X5-1", "url": "https://www.uniprot.org/uniprotkb/F1NTA5/entry#A0A8V1A4X5-1", "sequence": { "sequence": "MAGYTTLIQYKGKLNQVVGTKMIWVAVIGDWFNLIFKWILFGHRPYWWVHETMIYPNQSSPCLEQFPITCETGPGSPSGHAMGSSCVWYVMVTAALSYTVRWKEKSAVTLHRLTWSLLWTIFWIIQISVCISRVFIATHFPHQVILGVFAGIVVAEAFEHTPAIQTASLRMYIKTNLFLFIFALGFYLVLKLLDIDLLWSVPKAKKWCANPDWINIDTTPFAGLVRNLGAFFGLGIGINSEMFITSCKGKNSCKLSFRVLCIAASLATLQLYNFVKIPTHTEYLFYILSFCKSAAMPLTVVALVPYCVHTLMRTTDKKCN", "length": 320, "header": "tr|A0A8V1A4X5-1|A0A8V1A4X5_CHICK Computationally mapped isoform of glucose-6-phosphatase OS=Gallus gallus OX=9031 GN=G6PC2 PE=3 SV=1 CANONICAL=F1NTA5-1" }, "locus": { "chromosome": "7", "start_pos": 18543971, "end_pos": 18539580, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010061932.1", "url": "https://www.ensembl.org/id/ENSGALT00010061932.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038238.1", "url": "https://www.ensembl.org/id/ENSGALP00010038238.1" } ] } }, { "isoform_ac": "F1NTA5-1", "url": "https://www.uniprot.org/uniprotkb/F1NTA5/entry#F1NTA5-1", "sequence": { "sequence": "MDLLHSNGVLIIQHLQRDYRAYQDFLNFMSHVGDPRNIFSFYFPLWFQLNQVVGTKMIWVAVIGDWFNLIFKWILFGHRPYWWVHETMIYPNQSSPCLEQFPITCETGPGSPSGHAMGSSCVWYVMVTAALSYTVRWKEKSAVTLHRLTWSLLWTIFWIIQISVCISRVFIATHFPHQVILGVFAGIVVAEAFEHTPAIQTASLRMYIKTNLFLFIFALGFYLVLKLLDIDLLWSVPKAKKWCANPDWINIDTTPFAGLVRNLGAFFGLGIGINSEMFITSCKGKNSCKLSFRVLCIAASLATLQLYNFVKIPTHTEYLFYILSFCKSAAMPLTVVALVPYCVHTLMRTTDKKCN", "length": 355, "header": "tr|F1NTA5-1|F1NTA5_CHICK Isoform 1 of Glucose-6-phosphatase OS=Gallus gallus OX=9031 GN=G6PC2 PE=3 SV=4 CANONICAL=F1NTA5-1" }, "locus": { "chromosome": "7", "start_pos": 18543813, "end_pos": 18539580, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010061928.1", "url": "https://www.ensembl.org/id/ENSGALT00010061928.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038236.1", "url": "https://www.ensembl.org/id/ENSGALP00010038236.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "gga:424171", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424171", "resource": "KEGG Pathway" }, { "id": "R-GGA-70263", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-70263", "resource": "Reactome", "description": "Gluconeogenesis" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3L7HHB3-1", "protein_name": "Glucose-6-phosphatase", "gene_name": "G6pc2", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MDFLHRSRVLIIQHLQKDYRAYYNFLNFMSNVGDLRNIFSIYFPLWFQLNQTVGTKMIWVAVIGDWFNLIFKWILFGHRPYWWIQETQIYPNHSSPCLEQFPTTCETGPGSPSGHAMGSSCVWYVMVTAALSYTVSRLDKSSVTLHRLTWSCLWSVFWLIQVSVCISRVFIATHFPHQVILGIIGGMLVAEAFEHTPGIHMANLNVYLKTNIFLFLFALGFYLLLRLLDIDLLWSVPIAKKWCANPDWIHIDSTPFAGLVRNLGVLFGLGFAINSEMFLKSCQGENGDKLSFQLLCAITSLATLQLYHFIKIPTHREPLFYLLSFCKSASIPLTVVALIPYCVHMFMRASEKKTK", "length": 355 }, "evidence": [ { "id": "F1NTA5", "url": "https://omabrowser.org/oma/group/F1NTA5/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A4X1VN24-1", "protein_name": "Glucose-6-phosphatase", "gene_name": "G6PC2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDFLHRNGVLLIQHLQKDYRAYYSFLNFMSNVGDPRNIFSIYFPLWFQLNQRVGTKMIWVAVIGDWFNLIFKWILFGHRPYWWVQETQIYPNHSSPCLEQFPTTCETGPGSPSGHAMGSSCVWYVMVTAALGHTIRWMDKSSTTLHRLTWSFLWSLFWLIQISVCISRVFIATHFPHQVILGVIGGMLVAEVFEHTPGIQTASLSTYLKTNLFLFLFALGLYLLLGLLDIDLLWSVPIAKKWCANPEWIHIDTTPFAGLVRNLGVLFGLGFAINSEMFLRSCRGENGYRLSFRLLCTMASLTTLQLYHFIKIPTQAEYLFYVLSFCKSASIPLTVVALIPYCIHALMKPSKKKIH", "length": 355 }, "evidence": [ { "id": "F1NTA5", "url": "https://omabrowser.org/oma/group/F1NTA5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1MSR0-1", "protein_name": "Glucose-6-phosphatase", "gene_name": "G6PC2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MDFLHRNGVLVIQHLQKDYRAYYNFLNFMSNVGDPRNIFSIYFPLWFQLNQTVGTKMIWVAVIGDWFNLIFKWILFGHRPYWWVQETQIYPNHSSPCLEQFPTTCETGPGSPSGHAMGSSCVWYVMVTAALSHTVSQMDKSFITLHRLTWSFLWSLFWLIQINVCISRVFIATHFPHQVILGVIGGVLVAEIFEYTPGIQTASLSVYLKTNLFLFLFALGFYLLLRHLDIDLLWSVPIAKKWCANPDWIHIDTTPFAGLVRNLGVLFGLGFAINSEMFLRSCRGENGYGLSFRLLCALVSLTTLQLYHFIKIPTDTEYLFYVLSFCKSASIPLTVVALIPYCIHMLMKPSAKKLN", "length": 355 }, "evidence": [ { "id": "F1NTA5", "url": "https://omabrowser.org/oma/group/F1NTA5/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q9NQR9-1", "protein_name": "Glucose-6-phosphatase 2", "gene_name": "G6PC2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDFLHRNGVLIIQHLQKDYRAYYTFLNFMSNVGDPRNIFFIYFPLCFQFNQTVGTKMIWVAVIGDWLNLIFKWILFGHRPYWWVQETQIYPNHSSPCLEQFPTTCETGPGSPSGHAMGASCVWYVMVTAALSHTVCGMDKFSITLHRLTWSFLWSVFWLIQISVCISRVFIATHFPHQVILGVIGGMLVAEAFEHTPGIQTASLGTYLKTNLFLFLFAVGFYLLLRVLNIDLLWSVPIAKKWCANPDWIHIDTTPFAGLVRNLGVLFGLGFAINSEMFLLSCRGGNNYTLSFRLLCALTSLTILQLYHFLQIPTHEEHLFYVLSFCKSASIPLTVVAFIPYSVHMLMKQSGKKSQ", "length": 355 }, "evidence": [ { "id": "F1NTA5", "url": "https://omabrowser.org/oma/group/F1NTA5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9Z186-1", "protein_name": "Glucose-6-phosphatase 2", "gene_name": "G6pc2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDFLHRSGVLIIHHLQEDYRTYYGFLNFMSNVGDPRNIFSIYFPLWFQLNQNVGTKMIWVAVIGDWFNLIFKWILFGHRPYWWIQETEIYPNHSSPCLEQFPTTCETGPGSPSGHAMGSSCVWYVMVTAALSYTISRMEESSVTLHRLTWSFLWSVFWLIQISVCISRVFIATHFPHQVILGVIGGMLVAEAFEHTPGVHMASLSVYLKTNVFLFLFALGFYLLLRLFGIDLLWSVPIAKKWCANPDWIHIDSTPFAGLVRNLGVLFGLGFAINSEMFLRSCQGENGTKPSFRLLCALTSLTTMQLYRFIKIPTHAEPLFYLLSFCKSASIPLMVVALIPYCVHMLMRPGDKKTK", "length": 355 }, "evidence": [ { "id": "F1NTA5", "url": "https://omabrowser.org/oma/group/F1NTA5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "F1NTA5", "url": "https://www.uniprot.org/uniprotkb/F1NTA5" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "F1NTA5", "url": "https://www.uniprot.org/uniprotkb/F1NTA5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "gluconeogenesis", "id": "GO:0006094", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006094", "evidence": [ { "database": "UniProtKB", "id": "F1NTA5", "url": "https://www.uniprot.org/uniprotkb/F1NTA5" } ], "pmid": "" }, { "name": "glucose homeostasis", "id": "GO:0042593", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042593", "evidence": [ { "database": "UniProtKB", "id": "F1NTA5", "url": "https://www.uniprot.org/uniprotkb/F1NTA5" } ], "pmid": "" }, { "name": "regulation of insulin secretion", "id": "GO:0050796", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050796", "evidence": [ { "database": "UniProtKB", "id": "F1NTA5", "url": "https://www.uniprot.org/uniprotkb/F1NTA5" } ], "pmid": "" }, { "name": "glucose 6-phosphate metabolic process", "id": "GO:0051156", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051156", "evidence": [ { "database": "UniProtKB", "id": "F1NTA5", "url": "https://www.uniprot.org/uniprotkb/F1NTA5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "glucose-6-phosphatase activity", "id": "GO:0004346", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004346", "evidence": [ { "database": "UniProtKB", "id": "F1NTA5", "url": "https://www.uniprot.org/uniprotkb/F1NTA5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 92, "end_pos": 94, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "16689", "name": "", "equation": "D-glucose 6-phosphate + H2O = D-glucose + phosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A1D5PHE2-1", "A0A8V0ZVF2-1", "F1NTA5-1" ], "evidence": [ { "id": "16689", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/16689" } ] }, { "id": "R-GGA-3266566", "name": "G6PC2 hydrolyzes G6P to form Glc and Pi (islet)", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "endoplasmic reticulum lumen, endoplasmic reticulum membrane", "input_participant_list": [], "output_participant_list": [ "R-ALL-113780" ], "enzyme_list": [ "F1NTA5-1" ], "evidence": [ { "id": "R-GGA-3266566", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3266566" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-113780", "participant_name": "Glc [endoplasmic reticulum lumen]", "crossref": [ { "id": "C00031", "database": "COMPOUND", "url": "" }, { "id": "ZINC000003861213", "database": "ZINC", "url": "" }, { "id": "4167", "database": "ChEBI", "url": "" }, { "id": "G15021LG", "database": "GlyTouCan", "url": "" }, { "id": "ZINC000003833800", "database": "ZINC", "url": "" }, { "id": "4536", "database": "Guide to Pharmacology - Ligands", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A0A1D5PHE2", "gene_name": "IMPA1", "activity": [ { "ec_number": "3.1.3.25", "activity": "1D-myo-inositol 1-phosphate + H2O = myo-inositol + phosphate.", "evidence": [ { "id": "A0A1D5PHE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PHE2" } ] }, { "ec_number": "3.1.3.25", "activity": "", "evidence": [ { "id": "A0A1D5PHE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PHE2" } ] } ] }, { "uniprot_ac": "A0A8V0ZVF2", "gene_name": "G6PC", "activity": [ { "ec_number": "3.1.3.9", "activity": "alpha-D-glucose 6-phosphate + H2O = alpha-D-glucose + phosphate.", "evidence": [ { "id": "A0A8V0ZVF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVF2" } ] }, { "ec_number": "3.1.3.9", "activity": "", "evidence": [ { "id": "A0A8V0ZVF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVF2" } ] } ] }, { "uniprot_ac": "F1NTA5", "gene_name": "G6PC2", "activity": [ { "ec_number": "3.1.3.9", "activity": "alpha-D-glucose 6-phosphate + H2O = alpha-D-glucose + phosphate.", "evidence": [ { "id": "F1NTA5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NTA5" } ] }, { "ec_number": "3.1.3.9", "activity": "", "evidence": [ { "id": "F1NTA5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NTA5" } ] } ] } ], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1NTA5-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 355, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1NTA5-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1NTA5" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1NTA5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NTA5" }, { "id": "SM00014", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00014" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Phosphatidic acid phosphatase type 2/haloperoxidase", "eco_id": "ECO_0000259", "start_pos": 53, "end_pos": 194, "start_aa": "Val", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "3.1.3.9", "ec_name": "alpha-D-glucose 6-phosphate + H2O = alpha-D-glucose + phosphate.", "evidence": [ { "id": "3.1.3.9", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.9" }, { "id": "3.1.3.9", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=3.1.3.9" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 92, "end_pos": 94 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1NTY3-1", "uniprot_ac": "F1NTY3", "uniprot_id": "F1NTY3_CHICK", "mass": { "chemical_mass": 71705.0, "monoisotopic_mass": 71705.0 }, "refseq": { "ac": "XP_040557329", "name": "leucine-rich repeat-containing protein 4C", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040557329" }, "gene_names": [ { "name": "LRRC4C", "type": "recommended", "evidence": [ { "id": "F1NTY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NTY3" } ] }, { "name": "LRRC4C", "type": "synonym", "evidence": [ { "id": "XP_040557329", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040557329" } ] } ], "protein_names": [ { "name": "Leucine rich repeat containing 4C", "type": "synonym", "evidence": [ { "id": "F1NTY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NTY3/entry#names_and_taxonomy" } ] }, { "name": "leucine-rich repeat-containing protein 4C", "type": "synonym", "evidence": [ { "id": "XP_040557329", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040557329" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052536.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040557329", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040557329" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NTY3", "url": "https://www.uniprot.org/uniprotkb/F1NTY3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LRRC4C", "url": "https://www.uniprot.org/uniprotkb/F1NTY3", "locus": { "chromosome": "5", "start_pos": 19972777, "end_pos": 20480069, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010023696", "url": "https://www.ensembl.org/id/ENSGALG00010023696" } ] } } ], "crossref": [ { "id": "ENSGALG00000007948", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000007948", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "428862", "url": "https://www.ncbi.nlm.nih.gov/gene/428862", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000483", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000483", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001611", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001611", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003591", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003591", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003598", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003598", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013098", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013098", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050541", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050541", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:428862", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:428862", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "NVDEDCG", "url": "https://omabrowser.org/oma/group/NVDEDCG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1NTY3", "url": "https://www.orthodb.org/?gene=F1NTY3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24369", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24369", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24369:SF8", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24369:SF8", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00560", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00560", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07679", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07679", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13855", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13855", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_040557329", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040557329", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1NTY3", "url": "https://www.uniprot.org/uniprotkb/F1NTY3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NTY3-1", "url": "https://www.uniprot.org/uniprotkb/F1NTY3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLNKMTLHPQQIMIGPRFNRALFDPLLVVLLALQLLVVAGLVRAQTCPSVCSCSNQFSKVICVRKNLRDVPDGISTNTRLLNLHENQIQIIKVNSFKHLRHLEILQLSRNHIRTIEIGAFNGLANLNTLELFDNRLTTIPNGAFVYLSKLKELWLRNNPIESIPSYAFNRIPSLRRLDLGELKRLSYISEGAFEGLSNLRYLNLAMCNLREIPNLTPLVKLDELDLSGNHLTAIRPGSFQGLMHLQKLWMIQSQIQVIERNAFDNLQSLVEINLAHNNLTLLPHDLFTPLRLERIHLHHNPWNCNCDILWLSWWIKDKAPSNTACCARCHTPPSLKGRYIGELDLNYFTCYAPVIVEPPADLNVTEGMAAEMKCRASTSLTSVSWITPNGSVMTHGAYRVRIAVLSDGTLNFTKVTVQDTGLYTCMVSNSVGNTTASATLNVTALDNPGYTYFSTVTVETVEPSQDEAQTTEQVGPTPVTSWETTNMTTSLTPQSTRSTEKTFTIPVTDANNGIPGIDEVMKTTKIIIGCFVAITLMAAVMLVIFYKMRKQHHRQNHHAPTRTVEIINVDDELTGDTPIESHLPMPAIEHEHLNHYNSYKSPFNHTTTVNTINSIHSSVHEPLLIRMNSKDNVQETQI", "length": 638, "header": "tr|F1NTY3-1|F1NTY3_CHICK Isoform 1 of Leucine rich repeat containing 4C OS=Gallus gallus OX=9031 GN=LRRC4C PE=4 SV=2 CANONICAL=F1NTY3-1" }, "isoforms": [ { "isoform_ac": "F1NTY3-1", "url": "https://www.uniprot.org/uniprotkb/F1NTY3/entry#F1NTY3-1", "sequence": { "sequence": "MLNKMTLHPQQIMIGPRFNRALFDPLLVVLLALQLLVVAGLVRAQTCPSVCSCSNQFSKVICVRKNLRDVPDGISTNTRLLNLHENQIQIIKVNSFKHLRHLEILQLSRNHIRTIEIGAFNGLANLNTLELFDNRLTTIPNGAFVYLSKLKELWLRNNPIESIPSYAFNRIPSLRRLDLGELKRLSYISEGAFEGLSNLRYLNLAMCNLREIPNLTPLVKLDELDLSGNHLTAIRPGSFQGLMHLQKLWMIQSQIQVIERNAFDNLQSLVEINLAHNNLTLLPHDLFTPLRLERIHLHHNPWNCNCDILWLSWWIKDKAPSNTACCARCHTPPSLKGRYIGELDLNYFTCYAPVIVEPPADLNVTEGMAAEMKCRASTSLTSVSWITPNGSVMTHGAYRVRIAVLSDGTLNFTKVTVQDTGLYTCMVSNSVGNTTASATLNVTALDNPGYTYFSTVTVETVEPSQDEAQTTEQVGPTPVTSWETTNMTTSLTPQSTRSTEKTFTIPVTDANNGIPGIDEVMKTTKIIIGCFVAITLMAAVMLVIFYKMRKQHHRQNHHAPTRTVEIINVDDELTGDTPIESHLPMPAIEHEHLNHYNSYKSPFNHTTTVNTINSIHSSVHEPLLIRMNSKDNVQETQI", "length": 638, "header": "tr|F1NTY3-1|F1NTY3_CHICK Isoform 1 of Leucine rich repeat containing 4C OS=Gallus gallus OX=9031 GN=LRRC4C PE=4 SV=2 CANONICAL=F1NTY3-1" }, "locus": { "chromosome": "5", "start_pos": 20044838, "end_pos": 20042925, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010057775.1", "url": "https://www.ensembl.org/id/ENSGALT00010057775.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010035064.1", "url": "https://www.ensembl.org/id/ENSGALP00010035064.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 477, "start_aa": "Thr", "end_pos": 477, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr477", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:428862", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:428862", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2M0G8-1", "protein_name": "Leucine-rich repeat-containing protein 4C", "gene_name": "LOC100765202", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MLNKMTLHPQQIMIGPRFNRALFDPLLVVLLALQLLVVAGLVRAQTCPSVCSCSNQFSKVICVRKNLREVPDGISTNTRLLNLHENQIQIIKVNSFKHLRHLEILQLSRNHIRTIEIGAFNGLANLNTLELFDNRLTTIPNGAFVYLSKLKELWLRNNPIESIPSYAFNRIPSLRRLDLGELKRLSYISEGAFEGLSNLRYLNLAMCNLREIPNLTPLIKLDELDLSGNHLSAIRPGSFQGLMHLQKLWMIQSQIQVIERNAFDNLQSLVEINLAHNNLTLLPHDLFTPLHHLERIHLHHNPWNCNCDILWLSWWIRDMAPSNTACCARCNTPPNLKGRYIGELDQNYFTCYAPVIVEPPADLNVTEGMAAELKCRASTSLTSVSWITPNGTVMTHGAYKVRIAVLSDGTLNFTNVTVQDTGMYTCMVSNSVGNTTASATLNVTAATTTPFSYFSTVTVETMEPSQDEARTTDNNVGPTPVIDWETTNVTTSLTPQSTRSTEKTFTIPVTDINSGIPGIDEVMKTTKIIIGCFVAITLMAAVMLVIFYKMRKQHHRQNHHAPTRTVEIINVDDELTGDTPMESHLPMPAIEHEHLNHYNSYKSPFNHTTTVNTINSIHSSVHEPLLIRMNSKDNVQETQI", "length": 640 }, "evidence": [ { "id": "F1NTY3", "url": "https://omabrowser.org/oma/group/F1NTY3/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "D3ZXT1-1", "protein_name": "Leucine rich repeat containing 4C", "gene_name": "Lrrc4c", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLNKMTLHPQQIMIGPRFNRALFDPLLVVLLALQLLVVAGLVRAQTCPSVCSCSNQFSKVICVRKNLREVPDGISTNTRLLNLHENQIQIIKVNSFKHLRHLEILQLSRNHIRTIEIGAFNGLANLNTLELFDNRLTTIPNGAFVYLSKLKELWLRNNPIESIPSYAFNRIPSLRRLDLGELKRLSYISEGAFEGLSNLRYLNLAMCNLREIPNLTPLIKLDELDLSGNHLSAIRPGSFQGLMHLQKLWMIQSQIQVIERNAFDNLQSLVEINLAHNNLTLLPHDLFTPLHHLERIHLHHNPWNCNCDILWLSWWIRDMAPSNTACCARCNTPPNLKGRYIGELDQNYFTCYAPVIVEPPADLNVTEGMAAELKCRASTSLTSVSWITPNGTVMTHGAYKVRIAVLSDGTLNFTNVTVQDTGMYTCMVSNSVGNTTASATLNVTAATTTPFSYFSTVTVETMEPSQDEARTTDNNVGPTPVIDWETTNVTTSLTPQSTRSTEKTFTIPVTDINSGIPGIDEVMKTTKIIIGCFVAITLMAAVMLVIFYKMRKQHHRQNHHAPTRTVEIINVDDEITGDTPMESHLPMPAIEHEHLNHYNSYKSPFNHTTTVNTINSIHSSVHEPLLIRMNSKDNVQETQI", "length": 640 }, "evidence": [ { "id": "F1NTY3", "url": "https://omabrowser.org/oma/group/F1NTY3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1MXH5-1", "protein_name": "Leucine rich repeat containing 4C", "gene_name": "LRRC4C", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MLNKMTLHPQQIMIGPRFNRALFDPLLVVLLALQLLVVAGLVRAQTCPSVCSCSNQFSKVICVRKNLRDVPDGISTNTRLLNLHENQIQIIKVNSFKHLRHLEILQLSRNHIRTIEIGAFNGLANLNTLELFDNRLTTIPNGAFVYLSKLKELWLRNNPIESIPSYAFNRIPSLRRLDLGELKRLSYISEGAFEGLSNLRYLNLAMCNLREIPNLTPLIKLDELDLSGNHLSAIRPGSFQGLMHLQKLWMIQSQIQVIERNAFDNLQSLVEINLAHNNLTLLPHDLFTPLHHLERIHLHHNPWNCNCDILWLSWWIKDMAPSNTACCARCNTPPNLKGRYIGELDQNYFTCYAPVIVEPPADLNVTEGMAAELKCRASTSLTSVSWITPNGTVMTHGAYKVRIAVLSDGTLNFTNVTVQDTGMYTCMVSNSVGNTTASATLNVTAATTTPFSYFSTVTVETMEPSQDEARTTDNNVGPTPVIDWETTNVTTSLTPQSTRSTEKTFTIPVTDINSGIPGIDEVMKTTKIIIGCFVAITLMAAVMLVIFYKMRKQHHRQNHHAPTRTVEIINVDDEITGDTPMESHLPMPAIEHEHLNHYNSYKSPFNHTTTVNTINSIHSSVHEPLLIRMNSKDNVQETQI", "length": 640 }, "evidence": [ { "id": "F1NTY3", "url": "https://omabrowser.org/oma/group/F1NTY3/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1SHH6-1", "protein_name": "Leucine rich repeat containing 4C", "gene_name": "LRRC4C", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MLNKMTLHPQQIMIGPRFNRALFDPLLVVLLALQLLVVAGLVRAQTCPSVCSCSNQFSKVICVRKNLREVPDGISTNTRLLNLHENQIQIIKVNSFKHLRHLEILQLSRNHIRTIEIGAFNGLANLNTLELFDNRLTTIPNGAFVYLSKLKELWLRNNPIESIPSYAFNRIPSLRRLDLGELKRLSYISEGAFEGLSNLRYLNLAMCNLREIPNLTPLVKLDELDLSGNHLSAIRPGSFQGLMHLQKLWMIQSQIQVIERNAFDNLQSLVEINLAHNNLTLLPHDLFTPLHHLERIHLHHNPWNCNCDILWLSWWIKDMAPSNTACCARCNTPPNLKGRYIGELDQNYFTCYAPVIVEPPADLNVTEGMAAELKCRASTSLTSVSWITPNGTVMTHGAYKVRIAVLSDGTLNFTNVTVQDTGMYTCMVSNSVGNTTASATLNVTAATTTPFSYFSTVTVETMEPSQDEARTTDNNVGPTPVIDWETTNVTTSLTPQSTRSTEKTFTIPVTDINSGIPGIDEVMKTTKIIIGCFVAITLMAAVMLVIFYKMRKQHHRQNHHAPTRTVEIINVDDEITGDTPMESHLPMPAIEHEHLNHYNSYKSPFNHTTTVNTINSIHSSVHEPLLIRMNSKDNVQETQI", "length": 640 }, "evidence": [ { "id": "F1NTY3", "url": "https://omabrowser.org/oma/group/F1NTY3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q8C031-1", "protein_name": "Leucine-rich repeat-containing protein 4C", "gene_name": "Lrrc4c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLNKMTLHPQQIMIGPRFNRALFDPLLVVLLALQLLVVAGLVRAQTCPSVCSCSNQFSKVICVRKNLREVPDGISTNTRLLNLHENQIQIIKVNSFKHLRHLEILQLSRNHIRTIEIGAFNGLANLNTLELFDNRLTTIPNGAFVYLSKLKELWLRNNPIESIPSYAFNRIPSLRRLDLGELKRLSYISEGAFEGLSNLRYLNLAMCNLREIPNLTPLIKLDELDLSGNHLSAIRPGSFQGLMHLQKLWMIQSQIQVIERNAFDNLQSLVEINLAHNNLTLLPHDLFTPLHHLERIHLHHNPWNCNCDILWLSWWIRDMAPSNTACCARCNTPPNLKGRYIGELDQNYFTCYAPVIVEPPADLNVTEGMAAELKCRASTSLTSVSWITPNGTVMTHGAYKVRIAVLSDGTLNFTNVTVQDTGMYTCMVSNSVGNTTASATLNVTAATTTPFSYFSTVTVETMEPSQDEARTTDNNVGPTPVIDWETTNVTTSLTPQSTRSTEKTFTIPVTDINSGIPGIDEVMKTTKIIIGCFVAITLMAAVMLVIFYKMRKQHHRQNHHAPTRTVEIINVDDEITGDTPMESHLPMPAIEHEHLNHYNSYKSPFNHTTTVNTINSIHSSVHEPLLIRMNSKDNVQETQI", "length": 640 }, "evidence": [ { "id": "F1NTY3", "url": "https://omabrowser.org/oma/group/F1NTY3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9HCJ2-1", "protein_name": "Leucine-rich repeat-containing protein 4C", "gene_name": "LRRC4C", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLNKMTLHPQQIMIGPRFNRALFDPLLVVLLALQLLVVAGLVRAQTCPSVCSCSNQFSKVICVRKNLREVPDGISTNTRLLNLHENQIQIIKVNSFKHLRHLEILQLSRNHIRTIEIGAFNGLANLNTLELFDNRLTTIPNGAFVYLSKLKELWLRNNPIESIPSYAFNRIPSLRRLDLGELKRLSYISEGAFEGLSNLRYLNLAMCNLREIPNLTPLIKLDELDLSGNHLSAIRPGSFQGLMHLQKLWMIQSQIQVIERNAFDNLQSLVEINLAHNNLTLLPHDLFTPLHHLERIHLHHNPWNCNCDILWLSWWIKDMAPSNTACCARCNTPPNLKGRYIGELDQNYFTCYAPVIVEPPADLNVTEGMAAELKCRASTSLTSVSWITPNGTVMTHGAYKVRIAVLSDGTLNFTNVTVQDTGMYTCMVSNSVGNTTASATLNVTAATTTPFSYFSTVTVETMEPSQDEARTTDNNVGPTPVVDWETTNVTTSLTPQSTRSTEKTFTIPVTDINSGIPGIDEVMKTTKIIIGCFVAITLMAAVMLVIFYKMRKQHHRQNHHAPTRTVEIINVDDEITGDTPMESHLPMPAIEHEHLNHYNSYKSPFNHTTTVNTINSIHSSVHEPLLIRMNSKDNVQETQI", "length": 640 }, "evidence": [ { "id": "F1NTY3", "url": "https://omabrowser.org/oma/group/F1NTY3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "glutamatergic synapse", "id": "GO:0098978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098978", "evidence": [ { "database": "UniProtKB", "id": "F1NTY3", "url": "https://www.uniprot.org/uniprotkb/F1NTY3" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F1NTY3", "url": "https://www.uniprot.org/uniprotkb/F1NTY3" } ], "pmid": "" }, { "name": "postsynaptic density membrane", "id": "GO:0098839", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098839", "evidence": [ { "database": "UniProtKB", "id": "F1NTY3", "url": "https://www.uniprot.org/uniprotkb/F1NTY3" } ], "pmid": "" }, { "name": "Schaffer collateral - CA1 synapse", "id": "GO:0098685", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098685", "evidence": [ { "database": "UniProtKB", "id": "F1NTY3", "url": "https://www.uniprot.org/uniprotkb/F1NTY3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "regulation of axonogenesis", "id": "GO:0050770", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050770", "evidence": [ { "database": "UniProtKB", "id": "F1NTY3", "url": "https://www.uniprot.org/uniprotkb/F1NTY3" } ], "pmid": "" }, { "name": "modulation of chemical synaptic transmission", "id": "GO:0050804", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050804", "evidence": [ { "database": "UniProtKB", "id": "F1NTY3", "url": "https://www.uniprot.org/uniprotkb/F1NTY3" } ], "pmid": "" }, { "name": "synaptic membrane adhesion", "id": "GO:0099560", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099560", "evidence": [ { "database": "UniProtKB", "id": "F1NTY3", "url": "https://www.uniprot.org/uniprotkb/F1NTY3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "cell-cell adhesion mediator activity", "id": "GO:0098632", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098632", "evidence": [ { "database": "UniProtKB", "id": "F1NTY3", "url": "https://www.uniprot.org/uniprotkb/F1NTY3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 214, "end_pos": 216, "annotation": "n_glycosylation_sequon" }, { "start_pos": 278, "end_pos": 280, "annotation": "n_glycosylation_sequon" }, { "start_pos": 363, "end_pos": 365, "annotation": "n_glycosylation_sequon" }, { "start_pos": 389, "end_pos": 391, "annotation": "n_glycosylation_sequon" }, { "start_pos": 411, "end_pos": 413, "annotation": "n_glycosylation_sequon" }, { "start_pos": 433, "end_pos": 435, "annotation": "n_glycosylation_sequon" }, { "start_pos": 441, "end_pos": 443, "annotation": "n_glycosylation_sequon" }, { "start_pos": 486, "end_pos": 488, "annotation": "n_glycosylation_sequon" }, { "start_pos": 604, 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}, { "start_pos": 278, "end_pos": 280 }, { "start_pos": 363, "end_pos": 365 }, { "start_pos": 389, "end_pos": 391 }, { "start_pos": 411, "end_pos": 413 }, { "start_pos": 433, "end_pos": 435 }, { "start_pos": 441, "end_pos": 443 }, { "start_pos": 486, "end_pos": 488 }, { "start_pos": 604, "end_pos": 606 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", 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{ "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 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176066.0, "monoisotopic_mass": 176066.0 }, "refseq": { "ac": "XP_015144974", "name": "E3 ubiquitin-protein ligase HECW2 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015144974" }, "gene_names": [ { "name": "HECW2", "type": "recommended", "evidence": [ { "id": "F1NTZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NTZ8" } ] }, { "name": "HECW2", "type": "synonym", "evidence": [ { "id": "XP_015144974", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015144974" } ] } ], "protein_names": [ { "name": "HECT-type E3 ubiquitin transferase", "type": "recommended", "evidence": [ { "id": "F1NTZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NTZ8/entry#names_and_taxonomy" } ] }, { "name": "2.3.2.26", "type": "synonym", "evidence": [ { "id": "F1NTZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NTZ8/entry#names_and_taxonomy" } ] }, { "name": "E3 ubiquitin-protein ligase HECW2 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015144974", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015144974" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052538.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015144974", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015144974" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NTZ8", "url": "https://www.uniprot.org/uniprotkb/F1NTZ8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "HECW2", "url": "https://www.uniprot.org/uniprotkb/F1NTZ8", "locus": { "chromosome": "7", "start_pos": 9416796, "end_pos": 9592505, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010010928", "url": "https://www.ensembl.org/id/ENSGALG00010010928" } ] } } ], "crossref": [ { "id": "ENSGALG00000007944", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000007944", "database": 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Classification" ] }, { "id": "IPR050409", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050409", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:424050", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424050", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "TAGQHRE", "url": "https://omabrowser.org/oma/group/TAGQHRE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y8R0", "url": "https://www.orthodb.org/?gene=A0A8V0Y8R0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YAZ1", "url": "https://www.orthodb.org/?gene=A0A8V0YAZ1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NTZ8", "url": "https://www.orthodb.org/?gene=F1NTZ8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11254", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11254", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11254:SF127", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11254:SF127", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00168", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00168", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00397", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00397", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00632", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00632", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16562", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16562", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF18436", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18436", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-983168", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983168", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_015144974", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015144974", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Y8R0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y8R0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y8R0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y8R0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YAZ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAZ1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YAZ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAZ1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NTZ8", "url": "https://www.uniprot.org/uniprotkb/F1NTZ8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NTZ8-1", "url": 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"MASSAREHLLFVRRRNPQLRYTLSPENLQSLASQGTMAENMNLQRANSDTDLVTSDSRSSLTASMYEYTLGQSQNLIIFWDIKEEVDPTDWIGLYHIDENSPANFWDSKNRGVTGTQKGQIVWRIEPGPYFMESEIKICFKYYHGVSGALRATTPCITVKNPAVMMGVEGTDEGASGAQHSRKLVSFTLSDIRAVGLKKGMFFNPDPYLKMSIQPGKKSTFPTFAHHGQERRSTIISNTTNPVWHREKYSFVALLTDVLEIEVKDKFAKSRPIIKRFLGKLTIPVQRLLERHAIGDQILSYNLGRRLPADHVSGYLQFKVEITSSVHEDASPETVGTLLGVNSVNGDLGSPSDDEDMPTGHHDTSTVCSNGPILEESSGETIQRHPLRTSTTLETDQDELTSGASRSSPTRGRQDSLNDYLDAIEHNNHPRPGTSACGERPRGASPKLRSSFPTDTRLNAMLHIDSDEEEHELHQDLGFPSSLEDDGGLVMLNGATRNVERNGLSYSSDQVTQGPAEGENVSASEAPLPSTDDQTESLPELPPSQLVEGESLQGSQSETPADQAGSDSYTVQEAEQPPSSTDAGAADATVGSRRGVSETESIDQGSEPSQLSSETEQSDPARTESVSEASTRQEGESDVEGADSSCNESATVRRSSVEMRCSFESARFPETPAFSSQEEEEGACATDVARTEPVVETQDSPSTSGSLPAVQLPQEEVQEAEGGELQDQEDAEEIWQRRSLQAAAANSQSQDEETEGAQAACEGATAEVEGATGGAQANGHQPLRSLPSVRQDVSRYQRVDEALPPNWEARIDSHGRIFYVDHVNRTTTWQRPTAPPAPQILQRSNSIQQMEQLNRRYQSIRRTMTNDRPEEQTSAVDGAGEETDFHHSNADFRRENVLPHSTSRSRLTLLLQSPPVKFLISPEFFTVLHSNPSAYRMFTNNTCLKHMITKVRRDTHHFERYQHNRDLVGFLNMFANKQLELPRGWEMKHDHQGKAFFVDHNSRTTTFIDPRLPLQSSRPTSALVHRQHLTRQRSHSAGEVGEDSRHAGPPVLPRPSSTFNTVSRAQYQDVVPVAYNDKIVAFLRQPNIFEILQERQPDLTRNHSLREKIQFIRTEGTPGLVRLSSDADLVMLLSLFEEEIMSYVPPHALLHPSYCQSPRGSPVSSPQNSPGTQRANARAPAPYKRDFEAKLRNFYRKLETKGYGQGPGKLKLIIRRDHLLEDAFNQIMGYSRKDLQRNKLYVTFVGEEGLDYSGPSREFFFLVSRELFNPYYGLFEYSANDTYTVQISPMSAFVDNHHEWFRFSGRILGLALIHQYLLDAFFTRPFYKALLRILCDLSDLEYLDEEFHQSLQWMKDNDIHDILDLTFTVNEEVFGQITERELKPGGANIPVTEKNKKEYIERMVKWRIERGVVQQTESLVRGFYEVVDARLVSVFDARELELVIAGTAEIDLSDWRNNTEYRGGYHDNHIVIRWFWAAVERFNNEQRLRLLQFVTGTSSIPYEGFASLRGSNGPRRFCVEKWGKITALPRAHTCFNRLDLPPYPSFSMLYEKLLTAVEETSTFGLE", "length": 1566, "header": "tr|F1NTZ8-1|F1NTZ8_CHICK Isoform 1 of HECT-type E3 ubiquitin transferase OS=Gallus gallus OX=9031 GN=HECW2 PE=4 SV=2 CANONICAL=F1NTZ8-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Y8R0-1", "url": "https://www.uniprot.org/uniprotkb/F1NTZ8/entry#A0A8V0Y8R0-1", "sequence": { "sequence": "MQFKILRYPLEWPDENSPANFWDSKNRGVTGTQKGQIVWRIEPGPYFMESEIKICFKYYHGVSGALRATTPCITVKNPAVMMGVEGTDEGASGAQHSRKLVSFTLSDIRAVGLKKGMFFNPDPYLKMSIQPGKKSTFPTFAHHGQERRSTIISNTTNPVWHREKYSFVALLTDVLEIEVKDKFAKSRPIIKRFLGKLTIPVQRLLERHAIGDQILSYNLGRRLPADHVSGYLQFKVEITSSVHEDASPETVGTLLGVNSVNGDLGSPSDDEDMPTGHHDTSTVCSNGPILEESSGETIQRHPLRTSTTLETDQDELTSGASRSSPTRGRQDSLNDYLDAIEHNNHPRPGTSACGERPRGASPKLRSSFPTDTRLNAMLHIDSDEEEHELHQDLGFPSSLEDDGGLVMLNGATRNVERNGLSYSSDQVTQGPAEGENVSASEAPLPSTDDQTESLPELPPSQLVEGESLQGSQSETPADQAGSDSYTVQEAEQPPSSTDAGAADATVGSRRGVSETESIDQGSEPSQLSSETEQSDPARTESVSEASTRQEGESDVEGADSSCNESATVRRSSVEMRCSFESARFPETPAFSSQEEEEGACATDVARTEPVVETQDSPSTSGSLPAVQLPQEEVQEAEGGELQDQEDAEEIWQRRSLQAAAANSQSQDEETEGAQAACEGATAEVEGATGGAQANGHQPLRSLPSVRQDVSRYQRVDEALPPNWEARIDSHGRIFYVDHVNRTTTWQRPTAPPAPQILQRSNSIQQMEQLNRRYQSIRRTMTNDRPEEQTSAVDGAGEETDFHHSNADFRRENVLPHSTSRSRLTLLLQSPPVKFLISPEFFTVLHSNPSAYRMFTNNTCLKHMITKVRRDTHHFERYQHNRDLVGFLNMFANKQLELPRGWEMKHDHQGKAFFVDHNSRTTTFIDPRLPLQSSRPTSALVHRQHLTRQRSHSAGEVGEDSRHAGPPVLPRPSSTFNTVSRAQYQDVVPVAYNDKIVAFLRQPNIFEILQERQPDLTRNHSLREKIQFIRTEGTPGLVRLSSDADLVMLLSLFEEEIMSYVPPHALLHPSYCQSPRGSPVSSPQNSPGTQRANARAPAPYKRDFEAKLRNFYRKLETKGYGQGPGKLKLIIRRDHLLEDAFNQIMGYSRKDLQRNKLYVTFVGEEGLDYSGPSREFFFLVSRELFNPYYGLFEYSANDTYTVQISPMSAFVDNHHEWFRFSGRILGLALIHQYLLDAFFTRPFYKALLRILCDLSDLEYLDEEFHQSLQWMKDNDIHDILDLTFTVNEEVFGQITERELKPGGANIPVTEKNKKEYIERMVKWRIERGVVQQTESLVRGFYEVVDARLVSVFDARELELVIAGTAEIDLSDWRNNTEYRGGYHDNHIVIRWFWAAVERFNNEQRLRLLQFVTGTSSIPYEGFASLRGSNGPRRFCVEKWGKITALPRAHTCFNRLDLPPYPSFSMLYEKLLTAVEETSTFGLE", "length": 1482, "header": "tr|A0A8V0Y8R0-1|A0A8V0Y8R0_CHICK Computationally mapped isoform of HECT-type E3 ubiquitin transferase OS=Gallus gallus OX=9031 GN=HECW2 PE=4 SV=1 CANONICAL=F1NTZ8-1" }, "locus": { "chromosome": "7", "start_pos": 9496107, "end_pos": 9416950, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026169.1", "url": "https://www.ensembl.org/id/ENSGALT00010026169.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010014793.1", "url": "https://www.ensembl.org/id/ENSGALP00010014793.1" } ] } }, { "isoform_ac": "A0A8V0YAZ1-1", "url": "https://www.uniprot.org/uniprotkb/F1NTZ8/entry#A0A8V0YAZ1-1", "sequence": { "sequence": "MGVSSGSLCDGPRPDENSPANFWDSKNRGVTGTQKGQIVWRIEPGPYFMESEIKICFKYYHGVSGALRATTPCITVKNPAVMMGVEGTDEGASGAQHSRKLVSFTLSDIRAVGLKKGMFFNPDPYLKMSIQPGKKSTFPTFAHHGQERRSTIISNTTNPVWHREKYSFVALLTDVLEIEVKDKFAKSRPIIKRFLGKLTIPVQRLLERHAIGDQILSYNLGRRLPADHVSGYLQFKVEITSSVHEDASPETVGTLLGVNSVNGDLGSPSDDEDMPTGHHDTSTVCSNGPILEESSGETIQRHPLRTSTTLETDQDELTSGASRSSPTRGRQDSLNDYLDAIEHNNHPRPGTSACGERPRGASPKLRSSFPTDTRLNAMLHIDSDEEEHELHQDLGFPSSLEDDGGLVMLNGATRNVERNGLSYSSDQVTQGPAEGENVSASEAPLPSTDDQTESLPELPPSQLVEGESLQGSQSETPADQAGSDSYTVQEAEQPPSSTDAGAADATVGSRRGVSETESIDQGSEPSQLSSETEQSDPARTESVSEASTRQEGESDVEGADSSCNESATVRRSSVEMRCSFESARFPETPAFSSQEEEEGACATDVARTEPVVETQDSPSTSGSLPAVQLPQEEVQEAEGGELQDQEDAEEIWQRRSLQAAAANSQSQDEETEGAQAACEGATAEVEGATGGAQANGHQPLRSLPSVRQDVSRYQRVDEALPPNWEARIDSHGRIFYVDHVNRTTTWQRPTAPPAPQILQRSNSIQQMEQLNRRYQSIRRTMTNDRPEEQTSAVDGAGEETDFHHSNADFRRENVLPHSTSRSRLTLLLQSPPVKFLISPEFFTVLHSNPSAYRMFTNNTCLKHMITKVRRDTHHFERYQHNRDLVGFLNMFANKQLELPRGWEMKHDHQGKAFFVDHNSRTTTFIDPRLPLQSSRPTSALVHRQHLTRQRSHSAGEVGEDSRHAGPPVLPRPSSTFNTVSRAQYQDVVPVAYNDKIVAFLRQPNIFEILQERQPDLTRNHSLREKIQFIRTEGTPGLVRLSSDADLVMLLSLFEEEIMSYVPPHALLHPSYCQSPRGSPVSSPQNSPGTQRANARAPAPYKRDFEAKLRNFYRKLETKGYGQGPGKLKLIIRRDHLLEDAFNQIMGYSRKDLQRNKLYVTFVGEEGLDYSGPSREFFFLVSRELFNPYYGLFEYSANDTYTVQISPMSAFVDNHHEWFRFSGRILGLALIHQYLLDAFFTRPFYKALLRILCDLSDLEYLDEEFHQSLQWMKDNDIHDILDLTFTVNEEVFGQITERELKPGGANIPVTEKNKKEYIERMVKWRIERGVVQQTESLVRGFYEVVDARLVSVFDARELELVIAGTAEIDLSDWRNNTEYRGGYHDNHIVIRWFWAAVERFNNEQRLRLLQFVTGTSSIPYEGFASLRGSNGPRRFCVEKWGKITALPRAHTCFNRLDLPPYPSFSMLYEKLLTAVEETSTFGLE", "length": 1483, "header": "tr|A0A8V0YAZ1-1|A0A8V0YAZ1_CHICK Computationally mapped isoform of HECT-type E3 ubiquitin transferase OS=Gallus gallus OX=9031 GN=HECW2 PE=4 SV=1 CANONICAL=F1NTZ8-1" }, "locus": { "chromosome": "7", "start_pos": 9569936, "end_pos": 9416950, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026175.1", "url": "https://www.ensembl.org/id/ENSGALT00010026175.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010014799.1", "url": "https://www.ensembl.org/id/ENSGALP00010014799.1" } ] } }, { "isoform_ac": "F1NTZ8-1", "url": "https://www.uniprot.org/uniprotkb/F1NTZ8/entry#F1NTZ8-1", "sequence": { "sequence": "MASSAREHLLFVRRRNPQLRYTLSPENLQSLASQGTMAENMNLQRANSDTDLVTSDSRSSLTASMYEYTLGQSQNLIIFWDIKEEVDPTDWIGLYHIDENSPANFWDSKNRGVTGTQKGQIVWRIEPGPYFMESEIKICFKYYHGVSGALRATTPCITVKNPAVMMGVEGTDEGASGAQHSRKLVSFTLSDIRAVGLKKGMFFNPDPYLKMSIQPGKKSTFPTFAHHGQERRSTIISNTTNPVWHREKYSFVALLTDVLEIEVKDKFAKSRPIIKRFLGKLTIPVQRLLERHAIGDQILSYNLGRRLPADHVSGYLQFKVEITSSVHEDASPETVGTLLGVNSVNGDLGSPSDDEDMPTGHHDTSTVCSNGPILEESSGETIQRHPLRTSTTLETDQDELTSGASRSSPTRGRQDSLNDYLDAIEHNNHPRPGTSACGERPRGASPKLRSSFPTDTRLNAMLHIDSDEEEHELHQDLGFPSSLEDDGGLVMLNGATRNVERNGLSYSSDQVTQGPAEGENVSASEAPLPSTDDQTESLPELPPSQLVEGESLQGSQSETPADQAGSDSYTVQEAEQPPSSTDAGAADATVGSRRGVSETESIDQGSEPSQLSSETEQSDPARTESVSEASTRQEGESDVEGADSSCNESATVRRSSVEMRCSFESARFPETPAFSSQEEEEGACATDVARTEPVVETQDSPSTSGSLPAVQLPQEEVQEAEGGELQDQEDAEEIWQRRSLQAAAANSQSQDEETEGAQAACEGATAEVEGATGGAQANGHQPLRSLPSVRQDVSRYQRVDEALPPNWEARIDSHGRIFYVDHVNRTTTWQRPTAPPAPQILQRSNSIQQMEQLNRRYQSIRRTMTNDRPEEQTSAVDGAGEETDFHHSNADFRRENVLPHSTSRSRLTLLLQSPPVKFLISPEFFTVLHSNPSAYRMFTNNTCLKHMITKVRRDTHHFERYQHNRDLVGFLNMFANKQLELPRGWEMKHDHQGKAFFVDHNSRTTTFIDPRLPLQSSRPTSALVHRQHLTRQRSHSAGEVGEDSRHAGPPVLPRPSSTFNTVSRAQYQDVVPVAYNDKIVAFLRQPNIFEILQERQPDLTRNHSLREKIQFIRTEGTPGLVRLSSDADLVMLLSLFEEEIMSYVPPHALLHPSYCQSPRGSPVSSPQNSPGTQRANARAPAPYKRDFEAKLRNFYRKLETKGYGQGPGKLKLIIRRDHLLEDAFNQIMGYSRKDLQRNKLYVTFVGEEGLDYSGPSREFFFLVSRELFNPYYGLFEYSANDTYTVQISPMSAFVDNHHEWFRFSGRILGLALIHQYLLDAFFTRPFYKALLRILCDLSDLEYLDEEFHQSLQWMKDNDIHDILDLTFTVNEEVFGQITERELKPGGANIPVTEKNKKEYIERMVKWRIERGVVQQTESLVRGFYEVVDARLVSVFDARELELVIAGTAEIDLSDWRNNTEYRGGYHDNHIVIRWFWAAVERFNNEQRLRLLQFVTGTSSIPYEGFASLRGSNGPRRFCVEKWGKITALPRAHTCFNRLDLPPYPSFSMLYEKLLTAVEETSTFGLE", "length": 1566, "header": "tr|F1NTZ8-1|F1NTZ8_CHICK Isoform 1 of HECT-type E3 ubiquitin transferase OS=Gallus gallus OX=9031 GN=HECW2 PE=4 SV=2 CANONICAL=F1NTZ8-1" }, "locus": { "chromosome": "7", "start_pos": 9523601, "end_pos": 9416950, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026180.1", "url": "https://www.ensembl.org/id/ENSGALT00010026180.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010014804.1", "url": "https://www.ensembl.org/id/ENSGALP00010014804.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "gga:424050", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424050", "resource": "KEGG Pathway" }, { "id": "R-GGA-983168", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983168", "resource": "Reactome", "description": "Antigen processing: Ubiquitination & Proteasome degradation" } ], "orthologs": [ { "uniprot_canonical_ac": "D4ADD3-1", "protein_name": "HECT-type E3 ubiquitin transferase", "gene_name": "Hecw2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASSAREHLLFVRRRNPQMRYTLSPENLQSLATQNSMPENMALQRANSDTDLVTSESRSSLTASMYEYTLGQAQNLIIFWDIKEEVDPSDWIGLYHIDENSPANFWDSKNRGVTGTQKGQIVWRIEPGPYFMEPEIKICFKYYHGISGALRATTPCITVKNPAVMMGAEGMEGCASGSLHSRKLVSFTLSDLRAVGLKKGMFFNPDPYLKMSIQPGKKSSFPTCAHHGQERRSTIISNTTNPIWHREKYSFFALLTDVLEIEIKDKFAKSRPIIKRFLGKLTIPVQRLLERQAVGDQMLSYNLGRRLPADHVSGYLQFRVEVPSSAQEDASPEAVGTILGVHTVNGDLGSPSDDEDMPGSHHDSTICANGPVSEDSVADGTPKHSFRTSSTLEIDTEDLISTSSRNSPPRGRQDSLNDYLDAIEHNGPSRPGTASSSERPMGASPKLRSSFPTDTRLNAMLHIDSDEEDHDFQQDLGYPSSLEEEGGLIMCSRTSRIDDGSLTSQTKPEDDNPVENEDASVHETASLEERPENLPEVEDGSLPSGTAPDENEASVEPQPSADQGSTELCSSQEVDQPTSGTDAGASDTSVGSRRAASETESLDQGSEPSQVSSETEPSDPARTESVSEASTRPEGESDLEGADSSCNESVTTQLSSVETRCSSLESARFPETPAFSSQEEEDGACAAEPTSSGPTEGSQESVCTPGSLPAVQVPSREEEGSGAEATALSEQGELGEVWQRRGSLEGAAAAATAAATDSQPQEDGDPGDTQGACEGATAQEEGATGGSQTNGHQPLRSLPSVRQDVSRYQRVDEALPPNWEARIDSHGRIFYVDHVNRTTTWQRPTAPPAPQVLQRSNSIQQMEQLNRRYQSIRRTMTNERPEENTSAIDGAGEEADFHQASADFRRENVLPHSTSRSRLTLLLQSPPVKFLISPEFFTVLHSNPSAYRMFTNNTCLKHMITKVRRDTHHFERYQHNRDLVGFLNMFANKQLELPRGWEMKHDHQGKAFFVDHNSRTTTFIDPRLPLQSSRPTSALVHRQHLTRQRSHSAGEVGEDSRHAGPPVLPRPASTFNTVSRPQYQDMVPVAYNDKIVAFLRQPNILEILQERQPDLARNHSLREKIQFIRTEGTPGLVRLSSDADLVMLLSLFEEEIMSYVPPHALLHPSYCQSPRGSPVSSPQNSPGTQRANARAPAPYKRDFEAKLRNFYRKLETKGYGQGPGKLKLIIRRDHLLEDAFNQIMGYSRKDLQRNKLYVTFVGEEGLDYSGPSREFFFLVSRELFNPYYGLFEYSANDTYTVQISPMSAFVDNHHEWFRFSGRILGLALIHQYLLDAFFTRPFYKALLRILCDLSDLEYLDEEFHQSLQWMKDNDIHDILDLTFTVNEEVFGQITERELKPGGANIPVTEKNKKEYIERMVKWRIERGVVQQTESLVRGFYEVVDARLVSVFDARELELVIAGTAEIDLNDWRNNTEYRGGYHDNHIVIRWFWAAVERFNNEQRLRLLQFVTGTSSIPYEGFASLRGSNGPRRFCVEKWGKITALPRAHTCFNRLDLPPYPSFSMLYEKLLTAVEETSTFGLE", "length": 1578 }, "evidence": [ { "id": "F1NTZ8", "url": "https://omabrowser.org/oma/group/F1NTZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6I6G8-1", "protein_name": "E3 ubiquitin-protein ligase HECW2", "gene_name": "Hecw2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASSAREHLLFVRRRNPQMRYTLSPENLQSLAAQNSMPENMALQRANSDTDLVTSESRSSLTASMYEYTLGQAQNLIIFWDIKEEVDPSDWIGLYHIDENSPANFWDSKNRGVTGTQKGQIVWRIEPGPYFMEPEIKICFKYYHGISGALRATTPCITVKNPAVMMGAEGMEGGASGSLHSRKLVSFTLSDLRAVGLKKGMFFNPDPYLKMSIQPGKKSSFPTCAHHGQERRSTIISNTTNPIWHREKYSFFALLTDVLEIEIKDKFAKSRPIIKRFLGKLTIPVQRLLERQAGDQMLSYNLGRRLPADHVSGYLQFKVEVTSSAHEDASPEAVGTILGVHTVNGDLGSPSDEEDMPGSHHDSTICANGPVSEDSVADGTPKHSFRTSSTLEIDTEDLISTSSRNSPPRGRQDSLNDYLDAIEHNGPARPGAASSSERSMGASPKLRSSFPTDTRLNAMLHIDSDEEDHEFQQDLGYPSSLEEEGGLIMCSRASRIDDGSLTSQTKPEDDNPVENEDASIHETASLEERLENLPEVADGSLPSSTAPDENEANLEPQPSADQGSTELCSSQEVDQPTSGADAGASDTSGGSRRAASETESLDQGSEPSQVSSETEPSDPARTESVSEASTRPEGESDPEGADSSCNESVTTQLSSVETRCSSLESARFPETPAFSSQEEEDGACAAEPTSSGPAEGSQESVCTPSSLPAVQVPSREEEGSAAEAAALSEQGELGEVWQRRGSLEGAAAAAPAAAATDSQPQEDGDAGDAQGACEGATAQEEGATGGSQTNGHQPLRSLPSVRQDVSRYQRVDEALPPNWEARIDSHGRIFYVDHVNRTTTWQRPTAPPAPQVLQRSNSIQQMEQLNRRYQSIRRTMTNERPEENTSAIDGAGEEADFHQASADFRRENVLPHSTSRSRLTLLLQSPPVKFLISPEFFTVLHSNPSAYRMFTNNTCLKHMITKVRRDTHHFERYQHNRDLVGFLNMFANKQLELPRGWEMKHDHQGKAFFVDHNSRTTTFIDPRLPLQSSRPTSALVHRQHLTRQRSHSAGEVGEDSRHAGPPVLPRPSSTFNTVSRPQYQDMVPVAYNDKIVAFLRQPNILEILQERQPDLARNHSLREKIQFIRTEGTPGLVRLSSDADLVMLLSLFEEEIMSYVPPHALLHPSYCQSPRGSPVSSPQNSPGTQRANARAPAPYKRDFEAKLRNFYRKLETKGYGQGPGKLKLIIRRDHLLEDAFNQIMGYSRKDLQRNKLYVTFVGEEGLDYSGPSREFFFLVSRELFNPYYGLFEYSANDTYTVQISPMSAFVDNHHEWFRFSGRILGLALIHQYLLDAFFTRPFYKALLRILCDLSDLEYLDEEFHQSLQWMKDNDIHDILDLTFTVNEEVFGQITERELKPGGANIPVTEKNKKEYIERMVKWRIERGVVQQTESLVRGFYEVVDARLVSVFDARELELVIAGTAEIDLNDWRNNTEYRGGYHDNHIVIRWFWAAVERFNNEQRLRLLQFVTGTSSIPYEGFASLRGSNGPRRFCVEKWGKITALPRAHTCFNRLDLPPYPSFSMLYEKLLTAVEETSTFGLE", "length": 1578 }, "evidence": [ { "id": "F1NTZ8", "url": "https://omabrowser.org/oma/group/F1NTZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9P2P5-1", "protein_name": "E3 ubiquitin-protein ligase HECW2", "gene_name": "HECW2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MASSAREHLLFVRRRNPQMRYTLSPENLQSLAAQSSMPENMTLQRANSDTDLVTSESRSSLTASMYEYTLGQAQNLIIFWDIKEEVDPSDWIGLYHIDENSPANFWDSKNRGVTGTQKGQIVWRIEPGPYFMEPEIKICFKYYHGISGALRATTPCITVKNPAVMMGAEGMEGGASGNLHSRKLVSFTLSDLRAVGLKKGMFFNPDPYLKMSIQPGKKSSFPTCAHHGQERRSTIISNTTNPIWHREKYSFFALLTDVLEIEIKDKFAKSRPIIKRFLGKLTIPVQRLLERQAIGDQMLSYNLGRRLPADHVSGYLQFKVEVTSSVHEDASPEAVGTILGVNSVNGDLGSPSDDEDMPGSHHDSQVCSNGPVSEDSAADGTPKHSFRTSSTLEIDTEELTSTSSRTSPPRGRQDSLNDYLDAIEHNGHSRPGTATCSERSMGASPKLRSSFPTDTRLNAMLHIDSDEEDHEFQQDLGYPSSLEEEGGLIMFSRASRADDGSLTSQTKLEDNPVENEEASTHEAASFEDKPENLPELAESSLPAGPAPEEGEGGPEPQPSADQGSAELCGSQEVDQPTSGADTGTSDASGGSRRAVSETESLDQGSEPSQVSSETEPSDPARTESVSEASTRPEGESDLECADSSCNESVTTQLSSVDTRCSSLESARFPETPAFSSQEEEDGACAAEPTSSGPAEGSQESVCTAGSLPVVQVPSGEDEGPGAESATVPDQEELGEVWQRRGSLEGAAAAAESPPQEEGSAGEAQGTCEGATAQEEGATGGSQANGHQPLRSLPSVRQDVSRYQRVDEALPPNWEARIDSHGRIFYVDHVNRTTTWQRPTAPPAPQVLQRSNSIQQMEQLNRRYQSIRRTMTNERPEENTNAIDGAGEEADFHQASADFRRENILPHSTSRSRITLLLQSPPVKFLISPEFFTVLHSNPSAYRMFTNNTCLKHMITKVRRDTHHFERYQHNRDLVGFLNMFANKQLELPRGWEMKHDHQGKAFFVDHNSRTTTFIDPRLPLQSSRPTSALVHRQHLTRQRSHSAGEVGEDSRHAGPPVLPRPSSTFNTVSRPQYQDMVPVAYNDKIVAFLRQPNIFEILQERQPDLTRNHSLREKIQFIRTEGTPGLVRLSSDADLVMLLSLFEEEIMSYVPPHALLHPSYCQSPRGSPVSSPQNSPGTQRANARAPAPYKRDFEAKLRNFYRKLETKGYGQGPGKLKLIIRRDHLLEDAFNQIMGYSRKDLQRNKLYVTFVGEEGLDYSGPSREFFFLVSRELFNPYYGLFEYSANDTYTVQISPMSAFVDNHHEWFRFSGRILGLALIHQYLLDAFFTRPFYKALLRILCDLSDLEYLDEEFHQSLQWMKDNDIHDILDLTFTVNEEVFGQITERELKPGGANIPVTEKNKKEYIERMVKWRIERGVVQQTESLVRGFYEVVDARLVSVFDARELELVIAGTAEIDLSDWRNNTEYRGGYHDNHIVIRWFWAAVERFNNEQRLRLLQFVTGTSSIPYEGFASLRGSNGPRRFCVEKWGKITALPRAHTCFNRLDLPPYPSFSMLYEKLLTAVEETSTFGLE", "length": 1572 }, "evidence": [ { "id": "F1NTZ8", "url": "https://omabrowser.org/oma/group/F1NTZ8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1NTZ8", "url": "https://www.uniprot.org/uniprotkb/F1NTZ8" } ], "pmid": "" }, { "name": "mitotic spindle", "id": "GO:0072686", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072686", "evidence": [ { "database": "UniProtKB", "id": "F1NTZ8", "url": "https://www.uniprot.org/uniprotkb/F1NTZ8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "regulation of dendrite morphogenesis", "id": "GO:0048814", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048814", "evidence": [ { "database": "UniProtKB", "id": "F1NTZ8", "url": "https://www.uniprot.org/uniprotkb/F1NTZ8" } ], "pmid": "" }, { "name": "ubiquitin-dependent protein catabolic process", "id": "GO:0006511", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006511", "evidence": [ { "database": "UniProtKB", "id": "F1NTZ8", "url": "https://www.uniprot.org/uniprotkb/F1NTZ8" } ], "pmid": "" }, { "name": "regulation of mitotic metaphase/anaphase transition", "id": "GO:0030071", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030071", "evidence": [ { "database": "UniProtKB", "id": "F1NTZ8", "url": "https://www.uniprot.org/uniprotkb/F1NTZ8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "F1NTZ8", "url": "https://www.uniprot.org/uniprotkb/F1NTZ8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1102, "end_pos": 1104, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1280, "end_pos": 1282, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1457, "end_pos": 1459, "annotation": "n_glycosylation_sequon" }, { "start_pos": 238, "end_pos": 240, "annotation": "n_glycosylation_sequon" }, { "start_pos": 520, "end_pos": 522, "annotation": "n_glycosylation_sequon" }, { "start_pos": 647, "end_pos": 649, "annotation": "n_glycosylation_sequon" }, { "start_pos": 824, "end_pos": 826, "annotation": "n_glycosylation_sequon" }, { "start_pos": 940, "end_pos": 942, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-GGA-983140", "name": "Transfer of Ub from E2 to substrate and release of E2", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0X324-1", "A0A8V0XEM6-1", "A0A8V0XJC4-1", "A0A8V0XQR1-1", "A0A8V1AC19-1", "A0A8V1AC55-1", "A0A8V1AKB8-1", "A0A8V1ALH0-1", "F1NL19-1", "F1NRC6-1", "F1NTZ8-1", "A0A8V0YHL7-1", "A0A8V0YPW4-1", "A0A8V0YRM6-1", "A0A8V0YV22-1", "A0A8V0YVP3-1", "A0A8V0Z2L5-1", "F1NL77-1", "E1C982-1", "A0A3Q2UC96-1", "Q5ZKX6-1", "Z4YJC3-1", "A0A8V0XQU7-1", "A0A8V0Y5C9-1", "A0A8V1AL09-1", "A0A8V1AML5-1", "A0A8V1AP69-1", "F1NVY8-1", "R4GIV8-1", "A0A8V0ZJ49-1", "A0A8V0ZJV9-1", "A0A8V0ZL18-1", "A0A8V0ZM17-1", "A0A8V0ZSH4-1", "A0A8V0ZVX3-1", "A0A8V0ZW26-1", "A0A8V1A0Z6-1", "A0A8V0ZZH3-1", "A0A8V1A052-1", "A0A8V1A0X2-1", "A0A8V1A1I4-1", "A0A8V1A2W7-1", "A0A8V1A5P4-1", "A0A8V1A7T1-1", "A0A8V0XTY5-1", "A0A8V0Y5B5-1", "A0A8V0YL05-1", "A0A8V0Z082-1", "A0A8V0ZS27-1", "A0A8V1A9M0-1", "E1BZ35-1", "E1C3Q9-1", "F1NC08-1", "F1P2G0-1", "A0A8V0YY10-1", "A0A8V0YYC5-1", "A0A8V0Z1W7-1", "A0A8V0Z4C8-1", "A0A8V0Z596-1", "A0A1D5P284-1", "A0A8V0ZF21-1", "A0A3Q2U2G8-1", "A0A8V1A4H7-1", "A0A8V1A1N8-1", "A0A8V1A233-1", "A0A8V1A7P9-1", "A0A8V1ACU3-1", "A0A8V0ZSA3-1", "E1C656-1", "A0A8V0Y0Q7-1", "A0A8V0Y059-1", "A0A8V0Y5C7-1", "A0A8V0YCS7-1", "A0A8V0YDQ1-1", "A0A8V0YFD9-1", "A0A8V0YGF4-1", "A0A8V0YJK8-1", "A0A8V0YLY7-1", "A0A1D5NVE2-1", "A0A8V0ZKK3-1", "A0A8V0ZKQ3-1" ], "evidence": [ { "id": "R-GGA-983140", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983140" } ] }, { "id": "R-GGA-983147", "name": "Release of E3 from polyubiquitinated substrate", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XEM6-1", "A0A8V0XJC4-1", "A0A8V1AC55-1", "A0A8V1AKB8-1", "A0A8V1ALH0-1", "F1NRC6-1", "F1NTZ8-1", "A0A8V0YHL7-1", "A0A8V0YRM6-1", "A0A8V0YV22-1", "A0A8V0YVP3-1", "A0A8V0Z2L5-1", "F1NL77-1", "E1C982-1", "A0A3Q2UC96-1", "Z4YJC3-1", "A0A8V0XQU7-1", "A0A8V0Y5C9-1", "A0A8V1AL09-1", "A0A8V1AML5-1", "A0A8V1AP69-1", "F1NVY8-1", "A0A8V0ZJ49-1", "A0A8V0ZJV9-1", "A0A8V0ZL18-1", "A0A8V0ZM17-1", "A0A8V0ZSH4-1", "A0A8V0ZVX3-1", "A0A8V0ZW26-1", "A0A8V1A0Z6-1", "A0A8V0ZZH3-1", "A0A8V1A0X2-1", "A0A8V1A2W7-1", "A0A8V1A7T1-1", "A0A8V0XTY5-1", "A0A8V0Y5B5-1", "A0A8V0YL05-1", "A0A8V0ZS27-1", "A0A8V1A9M0-1", "E1BZ35-1", "E1C3Q9-1", "F1NC08-1", "F1P2G0-1", "A0A8V0YYC5-1", "A0A8V0Z4C8-1", "A0A8V0Z596-1", "A0A1D5P284-1", "A0A8V0ZF21-1", "A0A3Q2U2G8-1", "A0A8V1A1N8-1", "A0A8V1A233-1", "A0A8V1A7P9-1", "A0A8V0ZSA3-1", "E1C656-1", "A0A8V0Y0Q7-1", "A0A8V0Y5C7-1", "A0A8V0YCS7-1", "A0A8V0YDQ1-1", "A0A8V0YGF4-1", "A0A8V0YJK8-1", "A0A8V0YLY7-1", "A0A8V0ZKK3-1", "A0A8V0ZKQ3-1" ], "evidence": [ { "id": "R-GGA-983147", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983147" } ] }, { "id": "R-GGA-983156", "name": "Polyubiquitination of substrate", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0X324-1", "A0A8V0XEM6-1", "A0A8V0XJC4-1", "A0A8V0XQR1-1", "A0A8V1AC19-1", "A0A8V1AC55-1", "A0A8V1AKB8-1", "A0A8V1ALH0-1", "F1NL19-1", "F1NRC6-1", "F1NTZ8-1", "A0A8V0YHL7-1", "A0A8V0YPW4-1", "A0A8V0YRM6-1", "A0A8V0YV22-1", "A0A8V0YVP3-1", "A0A8V0Z2L5-1", "F1NL77-1", "E1C982-1", "A0A3Q2UC96-1", "Q5ZKX6-1", "Z4YJC3-1", "A0A8V0XQU7-1", "A0A8V0Y5C9-1", "A0A8V1AL09-1", "A0A8V1AML5-1", "A0A8V1AP69-1", "F1NVY8-1", "R4GIV8-1", "A0A8V0ZJ49-1", "A0A8V0ZJV9-1", "A0A8V0ZL18-1", "A0A8V0ZM17-1", "A0A8V0ZSH4-1", "A0A8V0ZVX3-1", "A0A8V0ZW26-1", "A0A8V1A0Z6-1", "A0A8V0ZZH3-1", "A0A8V1A052-1", "A0A8V1A0X2-1", "A0A8V1A1I4-1", "A0A8V1A2W7-1", "A0A8V1A5P4-1", "A0A8V1A7T1-1", "A0A8V0XTY5-1", "A0A8V0Y5B5-1", "A0A8V0YL05-1", "A0A8V0Z082-1", "A0A8V0ZS27-1", "A0A8V1A9M0-1", "E1BZ35-1", "E1C3Q9-1", "F1NC08-1", "F1P2G0-1", "A0A8V0YY10-1", "A0A8V0YYC5-1", "A0A8V0Z1W7-1", "A0A8V0Z4C8-1", "A0A8V0Z596-1", "A0A1D5P284-1", "A0A8V0ZF21-1", "A0A3Q2U2G8-1", "A0A8V1A4H7-1", "A0A8V1A1N8-1", "A0A8V1A233-1", "A0A8V1A7P9-1", "A0A8V1ACU3-1", "A0A8V0ZSA3-1", "E1C656-1", "A0A8V0Y0Q7-1", "A0A8V0Y059-1", "A0A8V0Y5C7-1", "A0A8V0YCS7-1", "A0A8V0YDQ1-1", "A0A8V0YFD9-1", "A0A8V0YGF4-1", "A0A8V0YJK8-1", "A0A8V0YLY7-1", "A0A1D5NVE2-1", "A0A8V0ZKK3-1", "A0A8V0ZKQ3-1" ], "evidence": [ { "id": "R-GGA-983156", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983156" } ] }, { "id": "R-GGA-983157", "name": "Interaction of E3 with substrate and E2-Ub complex", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0X324-1", "A0A8V0XEM6-1", "A0A8V0XJC4-1", "A0A8V0XQR1-1", "A0A8V1AC19-1", "A0A8V1AC55-1", "A0A8V1AKB8-1", "A0A8V1ALH0-1", "F1NL19-1", "F1NRC6-1", "F1NTZ8-1", "A0A8V0YHL7-1", "A0A8V0YPW4-1", "A0A8V0YRM6-1", "A0A8V0YV22-1", "A0A8V0YVP3-1", "A0A8V0Z2L5-1", "F1NL77-1", "E1C982-1", "A0A3Q2UC96-1", "Q5ZKX6-1", "Z4YJC3-1", "A0A8V0XQU7-1", "A0A8V0Y5C9-1", "A0A8V1AL09-1", "A0A8V1AML5-1", "A0A8V1AP69-1", "F1NVY8-1", "R4GIV8-1", "A0A8V0ZJ49-1", "A0A8V0ZJV9-1", "A0A8V0ZL18-1", "A0A8V0ZM17-1", "A0A8V0ZSH4-1", "A0A8V0ZVX3-1", "A0A8V0ZW26-1", "A0A8V1A0Z6-1", "A0A8V0ZZH3-1", "A0A8V1A052-1", "A0A8V1A0X2-1", "A0A8V1A1I4-1", "A0A8V1A2W7-1", "A0A8V1A5P4-1", "A0A8V1A7T1-1", "A0A8V0XTY5-1", "A0A8V0Y5B5-1", "A0A8V0YL05-1", "A0A8V0Z082-1", "A0A8V0ZS27-1", "A0A8V1A9M0-1", "E1BZ35-1", "E1C3Q9-1", "F1NC08-1", "F1P2G0-1", "A0A8V0YY10-1", "A0A8V0YYC5-1", "A0A8V0Z1W7-1", "A0A8V0Z4C8-1", "A0A8V0Z596-1", "A0A1D5P284-1", "A0A8V0ZF21-1", "A0A3Q2U2G8-1", "A0A8V1A4H7-1", "A0A8V1A1N8-1", "A0A8V1A233-1", "A0A8V1A7P9-1", "A0A8V1ACU3-1", "A0A8V0ZSA3-1", "E1C656-1", "A0A8V0Y0Q7-1", "A0A8V0Y059-1", "A0A8V0Y5C7-1", "A0A8V0YCS7-1", "A0A8V0YDQ1-1", "A0A8V0YFD9-1", "A0A8V0YGF4-1", "A0A8V0YJK8-1", "A0A8V0YLY7-1", "A0A1D5NVE2-1", "A0A8V0ZKK3-1", "A0A8V0ZKQ3-1" ], "evidence": [ { "id": "R-GGA-983157", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983157" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A1D5NVE2", "gene_name": "UBE2Q1", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A1D5NVE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NVE2" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A1D5NVE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NVE2" } ] } ] }, { "uniprot_ac": "A0A1D5P284", "gene_name": "UBR2", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A1D5P284", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P284" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A1D5P284", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P284" } ] } ] }, { "uniprot_ac": "A0A3Q2U2G8", "gene_name": "TRIM9", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A3Q2U2G8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U2G8" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A3Q2U2G8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U2G8" } ] } ] }, { "uniprot_ac": "A0A3Q2UC96", "gene_name": "NEDD4L", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A3Q2UC96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UC96" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A3Q2UC96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UC96" } ] } ] }, { "uniprot_ac": "A0A8V0X324", "gene_name": "UBE2E1", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V0X324", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X324" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V0X324", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X324" } ] } ] }, { "uniprot_ac": "A0A8V0XEM6", "gene_name": "HERC2", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0XEM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEM6" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0XEM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEM6" } ] } ] }, { "uniprot_ac": "A0A8V0XJC4", "gene_name": "UBE3D", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0XJC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XJC4" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0XJC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XJC4" } ] } ] }, { "uniprot_ac": "A0A8V0XQR1", "gene_name": "UBE2H", "activity": [ { "ec_number": "2.3.2.24", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E1 ubiquitin-activating enzyme]-L-cysteine + N(6)-monoubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0XQR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQR1" } ] }, { "ec_number": "2.3.2.24", "activity": "", "evidence": [ { "id": "A0A8V0XQR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQR1" } ] } ] }, { "uniprot_ac": "A0A8V0XQU7", "gene_name": "RNF6", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0XQU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQU7" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0XQU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQU7" } ] } ] }, { "uniprot_ac": "A0A8V0XTY5", "gene_name": "SH3RF1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0XTY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XTY5" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0XTY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XTY5" } ] } ] }, { "uniprot_ac": "A0A8V0Y059", "gene_name": "UBE2D1", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V0Y059", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y059" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V0Y059", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y059" } ] } ] }, { "uniprot_ac": "A0A8V0Y0Q7", "gene_name": "RNF144B", "activity": [ { "ec_number": "2.3.2.31", "activity": "[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-N(6)-ubiquitinyl-L-lysine.", "evidence": [ { "id": "A0A8V0Y0Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y0Q7" } ] }, { "ec_number": "2.3.2.31", "activity": "", "evidence": [ { "id": "A0A8V0Y0Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y0Q7" } ] } ] }, { "uniprot_ac": "A0A8V0Y5B5", "gene_name": "LTN1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0Y5B5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5B5" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0Y5B5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5B5" } ] } ] }, { "uniprot_ac": "A0A8V0Y5C7", "gene_name": "CBLL1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0Y5C7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5C7" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0Y5C7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5C7" } ] } ] }, { "uniprot_ac": "A0A8V0Y5C9", "gene_name": "HERC3", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0Y5C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5C9" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0Y5C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5C9" } ] } ] }, { "uniprot_ac": "A0A8V0YCS7", "gene_name": "RNF19A", "activity": [ { "ec_number": "2.3.2.31", "activity": "[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-N(6)-ubiquitinyl-L-lysine.", "evidence": [ { "id": "A0A8V0YCS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCS7" } ] }, { "ec_number": "2.3.2.31", "activity": "", "evidence": [ { "id": "A0A8V0YCS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCS7" } ] } ] }, { "uniprot_ac": "A0A8V0YDQ1", "gene_name": "WWP1", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YDQ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDQ1" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0YDQ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDQ1" } ] } ] }, { "uniprot_ac": "A0A8V0YFD9", "gene_name": "UBE2D2", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V0YFD9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFD9" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V0YFD9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFD9" } ] } ] }, { "uniprot_ac": "A0A8V0YGF4", "gene_name": "MYLIP", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YGF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGF4" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0YGF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGF4" } ] } ] }, { "uniprot_ac": "A0A8V0YHL7", "gene_name": "RNF114", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YHL7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHL7" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0YHL7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHL7" } ] } ] }, { "uniprot_ac": "A0A8V0YJK8", "gene_name": "RNF14", "activity": [ { "ec_number": "2.3.2.31", "activity": "[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-N(6)-ubiquitinyl-L-lysine.", "evidence": [ { "id": "A0A8V0YJK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJK8" } ] }, { "ec_number": "2.3.2.31", "activity": "", "evidence": [ { "id": "A0A8V0YJK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJK8" } ] } ] }, { "uniprot_ac": "A0A8V0YL05", "gene_name": "UBE3A", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YL05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL05" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0YL05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL05" } ] } ] }, { "uniprot_ac": "A0A8V0YLY7", "gene_name": "MKRN4P", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YLY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLY7" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0YLY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLY7" } ] } ] }, { "uniprot_ac": "A0A8V0YPW4", "gene_name": "UBE2J2", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V0YPW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPW4" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V0YPW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPW4" } ] } ] }, { "uniprot_ac": "A0A8V0YRM6", "gene_name": "RNF130", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YRM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRM6" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0YRM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRM6" } ] } ] }, { "uniprot_ac": "A0A8V0YV22", "gene_name": "RNF4", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YV22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YV22" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0YV22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YV22" } ] } ] }, { "uniprot_ac": "A0A8V0YVP3", "gene_name": "RBBP6", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YVP3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YVP3" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0YVP3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YVP3" } ] } ] }, { "uniprot_ac": "A0A8V0YY10", "gene_name": "UBE2D3", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V0YY10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YY10" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V0YY10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YY10" } ] } ] }, { "uniprot_ac": "A0A8V0YYC5", "gene_name": "ZNRF2", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YYC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYC5" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0YYC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYC5" } ] } ] }, { "uniprot_ac": "A0A8V0Z082", "gene_name": "UBE2B", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V0Z082", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z082" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V0Z082", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z082" } ] } ] }, { "uniprot_ac": "A0A8V0Z1W7", "gene_name": "UBE2K", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V0Z1W7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1W7" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V0Z1W7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1W7" } ] } ] }, { "uniprot_ac": "A0A8V0Z2L5", "gene_name": "TRIM63", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0Z2L5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2L5" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0Z2L5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2L5" } ] } ] }, { "uniprot_ac": "A0A8V0Z4C8", "gene_name": "MGRN1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0Z4C8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4C8" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0Z4C8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4C8" } ] } ] }, { "uniprot_ac": "A0A8V0Z596", "gene_name": "STUB1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0Z596", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z596" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0Z596", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z596" } ] } ] }, { "uniprot_ac": "A0A8V0ZF21", "gene_name": "DTX3L", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZF21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF21" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0ZF21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF21" } ] } ] }, { "uniprot_ac": "A0A8V0ZJ49", "gene_name": "SMURF1", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZJ49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ49" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0ZJ49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ49" } ] } ] }, { "uniprot_ac": "A0A8V0ZJV9", "gene_name": "MIB2", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZJV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJV9" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0ZJV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJV9" } ] } ] }, { "uniprot_ac": "A0A8V0ZKK3", "gene_name": "UBE3B", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZKK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKK3" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0ZKK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKK3" } ] } ] }, { "uniprot_ac": "A0A8V0ZKQ3", "gene_name": "RNF25", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZKQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKQ3" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0ZKQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKQ3" } ] } ] }, { "uniprot_ac": "A0A8V0ZL18", "gene_name": "HECTD2", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZL18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZL18" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0ZL18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZL18" } ] } ] }, { "uniprot_ac": "A0A8V0ZM17", "gene_name": "UBR1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZM17", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM17" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0ZM17", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM17" } ] } ] }, { "uniprot_ac": "A0A8V0ZS27", "gene_name": "TRIP12", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZS27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS27" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0ZS27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS27" } ] } ] }, { "uniprot_ac": "A0A8V0ZSA3", "gene_name": "HERC4", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZSA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSA3" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0ZSA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSA3" } ] } ] }, { "uniprot_ac": "A0A8V0ZSH4", "gene_name": "RNF111", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZSH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSH4" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0ZSH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSH4" } ] } ] }, { "uniprot_ac": "A0A8V0ZVX3", "gene_name": "NEDD4", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZVX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVX3" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0ZVX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVX3" } ] } ] }, { "uniprot_ac": "A0A8V0ZW26", "gene_name": "ZNRF1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZW26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZW26" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0ZW26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZW26" } ] } ] }, { "uniprot_ac": "A0A8V0ZZH3", "gene_name": "ITCH", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZZH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZH3" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0ZZH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZH3" } ] } ] }, { "uniprot_ac": "A0A8V1A052", "gene_name": "UBE2E3", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V1A052", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A052" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V1A052", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A052" } ] } ] }, { "uniprot_ac": "A0A8V1A0X2", "gene_name": "UBE3C", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1A0X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0X2" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V1A0X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0X2" } ] } ] }, { "uniprot_ac": "A0A8V1A0Z6", "gene_name": "UBE4A", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1A0Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0Z6" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1A0Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0Z6" } ] } ] }, { "uniprot_ac": "A0A8V1A1I4", "gene_name": "UBE2Z", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V1A1I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1I4" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V1A1I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1I4" } ] } ] }, { "uniprot_ac": "A0A8V1A1N8", "gene_name": "HERC1", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1A1N8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1N8" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V1A1N8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1N8" } ] } ] }, { "uniprot_ac": "A0A8V1A233", "gene_name": "RNF220", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1A233", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A233" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1A233", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A233" } ] } ] }, { "uniprot_ac": "A0A8V1A2W7", "gene_name": "RNF41", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1A2W7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2W7" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1A2W7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2W7" } ] } ] }, { "uniprot_ac": "A0A8V1A4H7", "gene_name": "UBE2L3", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V1A4H7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4H7" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V1A4H7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4H7" } ] } ] }, { "uniprot_ac": "A0A8V1A5P4", "gene_name": "UBE2G2", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V1A5P4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5P4" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V1A5P4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5P4" } ] } ] }, { "uniprot_ac": "A0A8V1A7P9", "gene_name": "DCAF1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A7P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P9" } ] } ] }, { "uniprot_ac": "A0A8V1A7T1", "gene_name": "RNF123", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1A7T1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7T1" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1A7T1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7T1" } ] } ] }, { "uniprot_ac": "A0A8V1A9M0", "gene_name": "RNF34", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1A9M0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9M0" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1A9M0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9M0" } ] } ] }, { "uniprot_ac": "A0A8V1AC19", "gene_name": "UBA7", "activity": [ { "ec_number": "6.2.1.45", "activity": "ATP + ubiquitin + [E1 ubiquitin-activating enzyme]-L-cysteine = AMP + diphosphate + S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V1AC19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC19" } ] }, { "ec_number": "6.2.1.45", "activity": "", "evidence": [ { "id": "A0A8V1AC19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC19" } ] } ] }, { "uniprot_ac": "A0A8V1AC55", "gene_name": "SMURF2", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1AC55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC55" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V1AC55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC55" } ] } ] }, { "uniprot_ac": "A0A8V1ACU3", "gene_name": "UBE2O", "activity": [ { "ec_number": "2.3.2.24", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E1 ubiquitin-activating enzyme]-L-cysteine + N(6)-monoubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1ACU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACU3" } ] }, { "ec_number": "2.3.2.24", "activity": "", "evidence": [ { "id": "A0A8V1ACU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACU3" } ] } ] }, { "uniprot_ac": "A0A8V1AKB8", "gene_name": "TRIM32", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1AKB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKB8" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1AKB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKB8" } ] } ] }, { "uniprot_ac": "A0A8V1AL09", "gene_name": "TRIM37", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1AL09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL09" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1AL09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL09" } ] } ] }, { "uniprot_ac": "A0A8V1ALH0", "gene_name": "RNF213", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1ALH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALH0" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1ALH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALH0" } ] } ] }, { "uniprot_ac": "A0A8V1AML5", "gene_name": "TRIM50", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1AML5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AML5" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1AML5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AML5" } ] } ] }, { "uniprot_ac": "A0A8V1AP69", "gene_name": "TRIM58", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1AP69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP69" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1AP69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP69" } ] } ] }, { "uniprot_ac": "E1BZ35", "gene_name": "RNF182", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1BZ35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BZ35" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "E1BZ35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BZ35" } ] } ] }, { "uniprot_ac": "E1C3Q9", "gene_name": "SIAH2", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 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"ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1C982", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C982" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "E1C982", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C982" } ] } ] }, { "uniprot_ac": "F1NC08", "gene_name": "RNF138", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1NC08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NC08" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "F1NC08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NC08" } ] } ] }, { "uniprot_ac": "F1NL19", "gene_name": "CDC34", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "F1NL19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NL19" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "F1NL19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NL19" } ] } ] }, { "uniprot_ac": "F1NL77", "gene_name": "CBLB", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1NL77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NL77" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "F1NL77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NL77" } ] } ] }, { "uniprot_ac": "F1NRC6", "gene_name": "RLIM", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1NRC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NRC6" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "F1NRC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NRC6" } ] } ] }, { "uniprot_ac": "F1NTZ8", "gene_name": "HECW2", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1NTZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NTZ8" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "F1NTZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NTZ8" } ] } ] }, { "uniprot_ac": "F1NVY8", "gene_name": "LNX1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1NVY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NVY8" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "F1NVY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NVY8" } ] } ] }, { "uniprot_ac": "F1P2G0", "gene_name": "SIAH1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1P2G0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P2G0" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "F1P2G0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P2G0" } ] } ] }, { "uniprot_ac": "Q5ZKX6", "gene_name": "UBE2F", "activity": [ { "ec_number": "2.3.2.34", "activity": "[E1 NEDD8-activating enzyme]-S-[NEDD8 protein]-yl-L-cysteine + [E2 NEDD8-conjugating enzyme]-L-cysteine = [E1 NEDD8-activating enzyme]-L-cysteine + [E2 NEDD8-conjugating enzyme]-S-[NEDD8-protein]-yl-L-cysteine.", "evidence": [ { "id": "Q5ZKX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKX6" } ] }, { "ec_number": "2.3.2.34", "activity": "", "evidence": [ { "id": "Q5ZKX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKX6" } ] } ] }, { "uniprot_ac": "R4GIV8", "gene_name": "UBE2R2", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "R4GIV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GIV8" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "R4GIV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GIV8" } ] } ] }, { "uniprot_ac": "Z4YJC3", "gene_name": "TRIM71", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "Z4YJC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Z4YJC3" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "Z4YJC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Z4YJC3" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.3.2.26", "ec_name": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "2.3.2.26", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.3.2.26" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1102, "end_pos": 1104 }, { "start_pos": 1280, "end_pos": 1282 }, { "start_pos": 1457, "end_pos": 1459 }, { "start_pos": 238, "end_pos": 240 }, { "start_pos": 520, "end_pos": 522 }, { "start_pos": 647, "end_pos": 649 }, { "start_pos": 824, "end_pos": 826 }, { "start_pos": 940, "end_pos": 942 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1NU06-1", "uniprot_ac": "F1NU06", "uniprot_id": "F1NU06_CHICK", "mass": { "chemical_mass": 15121.0, "monoisotopic_mass": 15121.0 }, "refseq": { "ac": "NP_001265053", "name": "mitochondrial pyruvate carrier 2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001265053" }, "gene_names": [ { "name": "MPC2", "type": "recommended", "evidence": [ { "id": "F1NU06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NU06" } ] }, { "name": "BRP44", "type": "synonym", "evidence": [ { "id": "NP_001265053", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001265053" } ] }, { "name": "MPC2", "type": "synonym", "evidence": [ { "id": "NP_001265053", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001265053" } ] } ], "protein_names": [ { "name": "Mitochondrial pyruvate carrier", "type": "recommended", "evidence": [ { "id": "F1NU06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NU06/entry#names_and_taxonomy" } ] }, { "name": "brain protein 44", "type": "synonym", "evidence": [ { "id": "NP_001265053", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001265053" } ] }, { "name": "mitochondrial pyruvate carrier 2", "type": "synonym", "evidence": [ { "id": "NP_001265053", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001265053" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: BU128760.1, BU143257.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: inferred from homology ##RefSeq-Attributes-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000019.1. On May 11, 2013 this sequence version replaced XP_001231387.2.", "evidence": [ { "database": "RefSeq", "id": "NP_001265053", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001265053" } ] }, { "annotation": "Mediates the uptake of pyruvate into mitochondria.", "evidence": [ { "database": "UniProtKB", "id": "F1NU06", "url": "https://www.uniprot.org/uniprotkb/F1NU06#function" }, { "database": "UniProtKB", "id": "RU363100", "url": "https://www.uniprot.org/uniprotkb/RU363100#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NU06", "url": "https://www.uniprot.org/uniprotkb/F1NU06" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MPC2", "url": "https://www.uniprot.org/uniprotkb/F1NU06", "locus": { "chromosome": "1", "start_pos": 91695262, "end_pos": 91679804, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010008067", "url": "https://www.ensembl.org/id/ENSGALG00010008067" } ] } } ], "crossref": [ { "id": "F1NU06", "url": "https://alphafold.ebi.ac.uk/entry/F1NU06", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000015437", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000015437", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "768451", "url": "https://www.ncbi.nlm.nih.gov/gene/768451", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR005336", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005336", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:768451", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:768451", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PQQFAIC", "url": "https://omabrowser.org/oma/group/PQQFAIC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1NU06", "url": "https://www.orthodb.org/?gene=F1NU06", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14154", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14154", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03650", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03650", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001265053", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001265053", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1NU06", "url": "https://www.uniprot.org/uniprotkb/F1NU06", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NU06-1", "url": "https://www.uniprot.org/uniprotkb/F1NU06-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAAVTGLRASYHRLLDRIELMLPPRFRPFYNHPAGPKTVFFWAPIMKWGLVCAGMADMTRPAEKLSTAQSAVLMATGLIWSRYSLVIIPKNWSLFAVNFFVGCAGGSQLFRIWRYNQELKAKQQEQLLQKDA", "length": 133, "header": "tr|F1NU06-1|F1NU06_CHICK Isoform 1 of Mitochondrial pyruvate carrier OS=Gallus gallus OX=9031 GN=MPC2 PE=1 SV=2 CANONICAL=F1NU06-1" }, "isoforms": [ { "isoform_ac": "F1NU06-1", "url": "https://www.uniprot.org/uniprotkb/F1NU06/entry#F1NU06-1", "sequence": { "sequence": "MAAAVTGLRASYHRLLDRIELMLPPRFRPFYNHPAGPKTVFFWAPIMKWGLVCAGMADMTRPAEKLSTAQSAVLMATGLIWSRYSLVIIPKNWSLFAVNFFVGCAGGSQLFRIWRYNQELKAKQQEQLLQKDA", "length": 133, "header": "tr|F1NU06-1|F1NU06_CHICK Isoform 1 of Mitochondrial pyruvate carrier OS=Gallus gallus OX=9031 GN=MPC2 PE=1 SV=2 CANONICAL=F1NU06-1" }, "locus": { "chromosome": "1", "start_pos": 91686383, "end_pos": 91679907, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010019238.1", "url": "https://www.ensembl.org/id/ENSGALT00010019238.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010010786.1", "url": "https://www.ensembl.org/id/ENSGALP00010010786.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:768451", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:768451", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A4X1V8M2-1", "protein_name": "Mitochondrial pyruvate carrier", "gene_name": "MPC2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSAAGARGLRATYHRVLDKVELLLPEKLRPLYNHPAGPRTVFFWAPIMKWGLVCAGLADMARPAEKLSTAQSAVLMATGFIWSRYSLVIIPKNWSLFAVNFFVGTAGASQLFRIWRYNQELKAKANK", "length": 127 }, "evidence": [ { "id": "F1NU06", "url": "https://omabrowser.org/oma/group/F1NU06/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A9J7JRV3-1", "protein_name": "Mitochondrial pyruvate carrier", "gene_name": "Mpc2", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAAAGARGLRASYHRLMDKVELLLPEKLRPLYNHPAGPRTVFFWAPIMKWGLVCAGLADMARPAEKLSTAQSTVLMATGFIWSRYSLVIIPKNWSLFAVNFFVGSAGASQLFRIWRYNQELKAKGIKSS", "length": 129 }, "evidence": [ { "id": "F1NU06", "url": "https://omabrowser.org/oma/group/F1NU06/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "E1BD64-1", "protein_name": "Mitochondrial pyruvate carrier", "gene_name": "MPC2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSAAGVRGLRATYHRVLDKVELLLPEKLRPLYNHPAGPRTVFFWAPIMKWGLVCAGLADMARPAEKLSTAQSAVLMATGFIWSRYSLVIIPKNWSLFAVNFFVGTAGASQLFRIWRYNQELKAKANK", "length": 127 }, "evidence": [ { "id": "F1NU06", "url": "https://omabrowser.org/oma/group/F1NU06/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "O49636-1", "protein_name": "Mitochondrial pyruvate carrier 4", "gene_name": "MPC4", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MATSKLQAIWNHPAGPKTIHFWAPTFKWGISIANIADFAKPPEKLSYPQQIAVTCTGVIWSRYSMVINPKNWNLFSVNVAMAGTGIYQLARKIKHDYATEAEPAVASE", "length": 108 }, "evidence": [ { "id": "F1NU06", "url": "https://omabrowser.org/oma/group/F1NU06/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "O95563-1", "protein_name": "Mitochondrial pyruvate carrier 2", "gene_name": "MPC2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSAAGARGLRATYHRLLDKVELMLPEKLRPLYNHPAGPRTVFFWAPIMKWGLVCAGLADMARPAEKLSTAQSAVLMATGFIWSRYSLVIIPKNWSLFAVNFFVGAAGASQLFRIWRYNQELKAKAHK", "length": 127 }, "evidence": [ { "id": "F1NU06", "url": "https://omabrowser.org/oma/group/F1NU06/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P38718-1", "protein_name": "Mitochondrial pyruvate carrier 2", "gene_name": "Mpc2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAAAGARGLRATYHRLMDKVELLLPKKLRPLYNHPAGPRTVFFWAPIMKWGLVCAGLADMARPAEKLSTAQSTVLMATGFIWSRYSLVIIPKNWSLFAVNFFVGSAGASQLFRIWKYNQELKSKGIQ", "length": 127 }, "evidence": [ { "id": "F1NU06", "url": "https://omabrowser.org/oma/group/F1NU06/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P53311-1", "protein_name": "Mitochondrial pyruvate carrier 3", "gene_name": "MPC3", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSASAFNFAFRRFWNSETGPKTVHFWAPTLKWGLVFAGLNDIKRPVEKVSGAQNLSLLATALIWTRWSFVIKPKNYLLASVNFFLGCTAGYHLTRIANFRIRNGDSFKQVIHYIIKGETPAAVAAKQTASTSMNKGVIGTNPPITH", "length": 146 }, "evidence": [ { "id": "F1NU06", "url": "https://omabrowser.org/oma/group/F1NU06/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q9D023-1", "protein_name": "Mitochondrial pyruvate carrier 2", "gene_name": "Mpc2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAAGARGLRATYHRLMDKVELLLPKKLRPLYNHPAGPRTVFFWAPIMKWGLVCAGLADMARPAEKLSTAQSTVLMATGFIWSRYSLVIIPKNWSLFAVNFFVGSAGASQLFRIWRYNQELKSKGIQ", "length": 127 }, "evidence": [ { "id": "F1NU06", "url": "https://omabrowser.org/oma/group/F1NU06/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VHB1-1", "protein_name": "Mitochondrial pyruvate carrier", "gene_name": "Mpc2a", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSSTAVQPPPPVPPPPPSAVPSAGKGIHSKLYNGMIGAADKFVPAKLRPLWMHPAGPKTIFFWAPVFKWGLVAAGLSDLARPADTISVSGCAALAATGIIWSRYSLVIIPKNYSLFAVNLFVGITQVVQLARAYHYHQSQEKLKQEQQQPAVQN", "length": 154 }, "evidence": [ { "id": "F1NU06", "url": "https://omabrowser.org/oma/group/F1NU06/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "F1NU06", "url": "https://www.uniprot.org/uniprotkb/F1NU06" } ], "pmid": "" }, { "name": "mitochondrial pyruvate carrier complex", "id": "GO:7770001", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:7770001", "evidence": [ { "database": "UniProtKB", "id": "F1NU06", "url": "https://www.uniprot.org/uniprotkb/F1NU06" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "F1NU06", "url": "https://www.uniprot.org/uniprotkb/F1NU06" } ], "pmid": "" }, { "name": "pyruvate transmembrane transporter activity", "id": "GO:0050833", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050833", "evidence": [ { "database": "UniProtKB", "id": "F1NU06", "url": "https://www.uniprot.org/uniprotkb/F1NU06" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "pyruvate import into mitochondria", "id": "GO:0006850", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006850", "evidence": [ { "database": "UniProtKB", "id": "F1NU06", "url": "https://www.uniprot.org/uniprotkb/F1NU06" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 92, "end_pos": 94, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1NU06-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 133, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1NU06-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1NU06" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 92, "end_pos": 94 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1NU37-1", "uniprot_ac": "F1NU37", "uniprot_id": "F1NU37_CHICK", "mass": { "chemical_mass": 34182.0, "monoisotopic_mass": 34182.0 }, "refseq": { "ac": "NP_001006297", "name": "replication termination factor 2 isoform 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006297" }, "gene_names": [ { "name": "RTFDC1", "type": "recommended", "evidence": [ { "id": "F1NU37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NU37" } ] }, { "name": "C20H20ORF43", "type": "synonym", "evidence": [ { "id": "NP_001006297", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006297" } ] }, { "name": "C20orf43", "type": "synonym", "evidence": [ { "id": "NP_001006297", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006297" } ] }, { "name": "CDAO5", "type": "synonym", "evidence": [ { "id": "NP_001006297", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006297" } ] }, { "name": "HSPC164", "type": "synonym", "evidence": [ { "id": "NP_001006297", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006297" } ] }, { "name": "RTF2", "type": "synonym", "evidence": [ { "id": "NP_001006297", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006297" } ] }, { "name": "RTFDC1", "type": "synonym", "evidence": [ { "id": "NP_001006297", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006297" } ] }, { "name": "SHUJUN-3", "type": "synonym", "evidence": [ { "id": "NP_001006297", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006297" } ] } ], "protein_names": [ { "name": "Replication termination factor 2", "type": "recommended", "evidence": [ { "id": "F1NU37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NU37/entry#names_and_taxonomy" } ] }, { "name": "Replication termination factor 2 domain-containing protein 1", "type": "synonym", "evidence": [ { "id": "F1NU37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NU37/entry#names_and_taxonomy" } ] }, { "name": "UPF0549 protein C20orf43 homolog", "type": "synonym", "evidence": [ { "id": "NP_001006297", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006297" } ] }, { "name": "protein RTF2 homolog", "type": "synonym", "evidence": [ { "id": "NP_001006297", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006297" } ] }, { "name": "replication termination factor 2 domain-containing protein 1", "type": "synonym", "evidence": [ { "id": "NP_001006297", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006297" } ] }, { "name": "replication termination factor 2 isoform 1", "type": "synonym", "evidence": [ { "id": "NP_001006297", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006297" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: HAEL01008393.1, HAEK01006032.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992437 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000328.1. On Feb 25, 2015 this sequence version replaced NP_001006297.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001006297", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006297" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NU37", "url": "https://www.uniprot.org/uniprotkb/F1NU37" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RTFDC1", "url": "https://www.uniprot.org/uniprotkb/F1NU37", "locus": { "chromosome": "20", "start_pos": 12310720, "end_pos": 12332913, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013228", "url": "https://www.ensembl.org/id/ENSGALG00010013228" } ] } } ], "crossref": [ { "id": "F1NU37", "url": "https://alphafold.ebi.ac.uk/entry/F1NU37", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000007709", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000007709", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd16653", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16653", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "419329", "url": "https://www.ncbi.nlm.nih.gov/gene/419329", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006735", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006735", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027799", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027799", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:419329", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419329", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "F1NU37", "url": "https://www.orthodb.org/?gene=F1NU37", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12775", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12775", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12775:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12775:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04641", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04641", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001006297", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006297", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1NU37", "url": "https://www.uniprot.org/uniprotkb/F1NU37", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NU37-1", "url": "https://www.uniprot.org/uniprotkb/F1NU37-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGCDGGTIPKRHELVKGPRKAVKVDKTAELVARWYYCTLSQEKLCRPIVACELGRLYNKDAVIEFLLDKSADKTPMEAASHIKSLKNVTELNLADNPAWSGDKESKKGDTYDDIQSARFICPVVGLEMNGRHRFCFLRNCGCVFSERALKEIKTEVCHKCGVPFQEEDVIILNGNKEDVEVLKKRMEDRRLKSKLEKKSKKCKSAESAAQQVTTEDSPGPSKVKNSKDCIASSSGEKRHIIFTKSSDDRSSSVPGKVNKASTATKRSIADSDEKSEAYKSIFTTHSSAKRPKEECSNWVTHTAYCF", "length": 306, "header": "tr|F1NU37-1|F1NU37_CHICK Isoform 1 of Replication termination factor 2 OS=Gallus gallus OX=9031 GN=RTFDC1 PE=3 SV=2 CANONICAL=F1NU37-1" }, "isoforms": [ { "isoform_ac": "F1NU37-1", "url": "https://www.uniprot.org/uniprotkb/F1NU37/entry#F1NU37-1", "sequence": { "sequence": "MGCDGGTIPKRHELVKGPRKAVKVDKTAELVARWYYCTLSQEKLCRPIVACELGRLYNKDAVIEFLLDKSADKTPMEAASHIKSLKNVTELNLADNPAWSGDKESKKGDTYDDIQSARFICPVVGLEMNGRHRFCFLRNCGCVFSERALKEIKTEVCHKCGVPFQEEDVIILNGNKEDVEVLKKRMEDRRLKSKLEKKSKKCKSAESAAQQVTTEDSPGPSKVKNSKDCIASSSGEKRHIIFTKSSDDRSSSVPGKVNKASTATKRSIADSDEKSEAYKSIFTTHSSAKRPKEECSNWVTHTAYCF", "length": 306, "header": "tr|F1NU37-1|F1NU37_CHICK Isoform 1 of Replication termination factor 2 OS=Gallus gallus OX=9031 GN=RTFDC1 PE=3 SV=2 CANONICAL=F1NU37-1" }, "locus": { "chromosome": "20", "start_pos": 12332869, "end_pos": 12312641, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031770.1", "url": "https://www.ensembl.org/id/ENSGALT00010031770.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018595.1", "url": "https://www.ensembl.org/id/ENSGALP00010018595.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:419329", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419329", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "F1NU37", "url": "https://www.uniprot.org/uniprotkb/F1NU37" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1NU37", "url": "https://www.uniprot.org/uniprotkb/F1NU37" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "F1NU37", "url": "https://www.uniprot.org/uniprotkb/F1NU37" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "F1NU37", "url": "https://www.uniprot.org/uniprotkb/F1NU37" } ], "pmid": "" }, { "name": "replication fork", "id": "GO:0005657", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005657", "evidence": [ { "database": "UniProtKB", "id": "F1NU37", "url": "https://www.uniprot.org/uniprotkb/F1NU37" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "regulation of DNA stability", "id": "GO:0097752", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097752", "evidence": [ { "database": "UniProtKB", "id": "F1NU37", "url": "https://www.uniprot.org/uniprotkb/F1NU37" } ], "pmid": "" }, { "name": "cellular response to hydroxyurea", "id": "GO:0072711", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072711", "evidence": [ { "database": "UniProtKB", "id": "F1NU37", "url": "https://www.uniprot.org/uniprotkb/F1NU37" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 87, "end_pos": 89, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1NU37-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 306, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1NU37-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1NU37" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 87, "end_pos": 89 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1NU38-1", "uniprot_ac": "F1NU38", "uniprot_id": "F1NU38_CHICK", "mass": { "chemical_mass": 31971.0, "monoisotopic_mass": 31971.0 }, "refseq": {}, "gene_names": [ { "name": "TRAPPC4", "type": "recommended", "evidence": [ { "id": "F1NU38", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NU38" } ] } ], "protein_names": [ { "name": "Trafficking protein particle complex subunit 4", "type": "recommended", "evidence": [ { "id": "F1NU38", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NU38/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Core component of the TRAPP complexes which has a function of guanine nucleotide exchange factor activity for Rab1 GTPase. Plays a role in vesicular transport from endoplasmic reticulum to Golgi and autophagy. May play a role in dendrite postsynaptic membrane trafficking.", "evidence": [ { "database": "UniProtKB", "id": "F1NU38", "url": "https://www.uniprot.org/uniprotkb/F1NU38#function" }, { "database": "UniProtKB", "id": "ARBA00046052", "url": "https://www.uniprot.org/uniprotkb/ARBA00046052#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NU38", "url": "https://www.uniprot.org/uniprotkb/F1NU38" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TRAPPC4", "url": "https://www.uniprot.org/uniprotkb/F1NU38", "locus": { "chromosome": "24", "start_pos": 5694292, "end_pos": 5692114, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010024866", "url": "https://www.ensembl.org/id/ENSGALG00010024866" } ] } } ], "crossref": [ { "id": "F1NU38", "url": "https://alphafold.ebi.ac.uk/entry/F1NU38", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000007707", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000007707", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd14856", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14856", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR007233", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007233", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011012", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011012", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "F1NU38", "url": "https://www.orthodb.org/?gene=F1NU38", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23249", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23249", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23249:SF15", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23249:SF15", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04099", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04099", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-204005", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-204005", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "F1NU38", "url": "https://www.uniprot.org/uniprotkb/F1NU38", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NU38-1", "url": "https://www.uniprot.org/uniprotkb/F1NU38-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MREGGSAQPLAPTPRRPPPAPRSPCCGCCCSQDVGRERKLRTRDGRKTLRRGAGAVTSLPPSDATTSLPRAGGAMAIFSVYVVNKAGGLIYQLDHYAPRSDTEKTFSYPLDLVLRPRDERVVVAFGQRDGIRVGHAVLAINGAEVNGRLTADGKDVLEFLSNPANYPVSIRFGRHRLSSNEKLMLASMFHSLFAIGSQLSPEVGSSGIEMLETDTFKLHCFQTLTGIKFVVLADPRQAGIDALLRKIYEIYSDFALKNPFYSLEMPIRCELFDQNLKLALEVAEKAGPFGPGS", "length": 293, "header": "tr|F1NU38-1|F1NU38_CHICK Isoform 1 of Trafficking protein particle complex subunit 4 OS=Gallus gallus OX=9031 GN=TRAPPC4 PE=1 SV=4 CANONICAL=F1NU38-1" }, "isoforms": [ { "isoform_ac": "F1NU38-1", "url": "https://www.uniprot.org/uniprotkb/F1NU38/entry#F1NU38-1", "sequence": { "sequence": "MREGGSAQPLAPTPRRPPPAPRSPCCGCCCSQDVGRERKLRTRDGRKTLRRGAGAVTSLPPSDATTSLPRAGGAMAIFSVYVVNKAGGLIYQLDHYAPRSDTEKTFSYPLDLVLRPRDERVVVAFGQRDGIRVGHAVLAINGAEVNGRLTADGKDVLEFLSNPANYPVSIRFGRHRLSSNEKLMLASMFHSLFAIGSQLSPEVGSSGIEMLETDTFKLHCFQTLTGIKFVVLADPRQAGIDALLRKIYEIYSDFALKNPFYSLEMPIRCELFDQNLKLALEVAEKAGPFGPGS", "length": 293, "header": "tr|F1NU38-1|F1NU38_CHICK Isoform 1 of Trafficking protein particle complex subunit 4 OS=Gallus gallus OX=9031 GN=TRAPPC4 PE=1 SV=4 CANONICAL=F1NU38-1" }, "locus": { "chromosome": "24", "start_pos": 5693901, "end_pos": 5692313, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010060711.1", "url": "https://www.ensembl.org/id/ENSGALT00010060711.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010037470.1", "url": "https://www.ensembl.org/id/ENSGALP00010037470.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-204005", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-204005", "resource": "Reactome", "description": "COPII-mediated vesicle transport" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 8, "go_terms": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "F1NU38", "url": "https://www.uniprot.org/uniprotkb/F1NU38" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "F1NU38", "url": "https://www.uniprot.org/uniprotkb/F1NU38" } ], "pmid": "" }, { "name": "dendrite", "id": "GO:0030425", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030425", "evidence": [ { "database": "UniProtKB", "id": "F1NU38", "url": "https://www.uniprot.org/uniprotkb/F1NU38" } ], "pmid": "" }, { "name": "presynaptic active zone", "id": "GO:0048786", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048786", "evidence": [ { "database": "UniProtKB", "id": "F1NU38", "url": "https://www.uniprot.org/uniprotkb/F1NU38" } ], "pmid": "" }, { "name": "Golgi stack", "id": "GO:0005795", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005795", "evidence": [ { "database": "UniProtKB", "id": "F1NU38", "url": "https://www.uniprot.org/uniprotkb/F1NU38" } ], "pmid": "" }, { "name": "synaptic vesicle", "id": "GO:0008021", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008021", "evidence": [ { "database": "UniProtKB", "id": "F1NU38", "url": "https://www.uniprot.org/uniprotkb/F1NU38" } ], "pmid": "" }, { "name": "postsynaptic density membrane", "id": "GO:0098839", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098839", "evidence": [ { "database": "UniProtKB", "id": "F1NU38", "url": "https://www.uniprot.org/uniprotkb/F1NU38" } ], "pmid": "" }, { "name": "TRAPP complex", "id": "GO:0030008", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030008", "evidence": [ { "database": "UniProtKB", "id": "F1NU38", "url": "https://www.uniprot.org/uniprotkb/F1NU38" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "dendrite development", "id": "GO:0016358", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016358", "evidence": [ { "database": "UniProtKB", "id": "F1NU38", "url": "https://www.uniprot.org/uniprotkb/F1NU38" } ], "pmid": "" }, { "name": "endoplasmic reticulum to Golgi vesicle-mediated transport", "id": "GO:0006888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006888", "evidence": [ { "database": "UniProtKB", "id": "F1NU38", "url": "https://www.uniprot.org/uniprotkb/F1NU38" } ], "pmid": "" }, { "name": "autophagy", "id": "GO:0006914", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006914", "evidence": [ { "database": "UniProtKB", "id": "F1NU38", "url": "https://www.uniprot.org/uniprotkb/F1NU38" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1NU38-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 293, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1NU38-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1NU38" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", 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"sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1NU59-1", "uniprot_ac": "F1NU59", "uniprot_id": "F1NU59_CHICK", "mass": { "chemical_mass": 49507.0, "monoisotopic_mass": 49507.0 }, "refseq": { "ac": "XP_003643070", "name": "beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003643070" }, "gene_names": [ { "name": "GCNT1", "type": "recommended", "evidence": [ { "id": "F1NU59", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NU59" } ] }, { "name": "GCNT1", "type": "synonym", "evidence": [ { "id": "XP_003643070", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003643070" } ] } ], "protein_names": [ { "name": "Glucosaminyl (N-acetyl) transferase 1", "type": "synonym", "evidence": [ { "id": "F1NU59", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NU59/entry#names_and_taxonomy" } ] }, { "name": "beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase", "type": "synonym", "evidence": [ { "id": "XP_003643070", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003643070" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052572.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003643070", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003643070" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NU59", "url": "https://www.uniprot.org/uniprotkb/F1NU59" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "GCNT1", "url": "https://www.uniprot.org/uniprotkb/F1NU59", "locus": { "chromosome": "Z", "start_pos": 37983918, "end_pos": 37963013, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010015132", "url": "https://www.ensembl.org/id/ENSGALG00010015132" } ] } } ], "crossref": [ { "id": "ENSGALG00000015166", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000015166", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "427260", "url": "https://www.ncbi.nlm.nih.gov/gene/427260", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003406", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003406", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:427260", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427260", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "NGKLTNM", "url": "https://omabrowser.org/oma/group/NGKLTNM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1NU59", "url": "https://www.orthodb.org/?gene=F1NU59", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR19297", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19297", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19297:SF96", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19297:SF96", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02485", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02485", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-913709", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-913709", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_003643070", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003643070", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1NU59", "url": "https://www.uniprot.org/uniprotkb/F1NU59", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NU59-1", "url": "https://www.uniprot.org/uniprotkb/F1NU59-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLKRKLRFFHNSCFRLFLGLTLILVIISVLKVNQKADFLNRRHLDLTKEDPIGDVNCTKILEGDIEEIQKVKLETLSVSFKKRPKLTTSDYINMTTDCSSFTKMRKYIMEPLSSEEAEFPIAYSIVVYHKIEMLDRLLRSIYAPQNFYCIHVDKKSPESFFTAVKGIVSCFDNVFISSQLESVVYASWSRVQADINCMKDLYRRSSNWKYLINLCGMDFPIKTNREIVEKLKALKGENSLETEKMPVYKEVRWKKHYEIVDGKVKNTGIDKQLPPLSTPIFSGSAYFVVSRRFVEYVLENSKILKFIEWAKDTYSPDEYLWATIQRIPDVPGAVSSSDKYDVSDMNALARFVKWQYFEGDVSKGAPYPPCSGIHVRSVCVFGVGDLNWMLRNHHFFANKFDTDVDPFAVKCLEEYLRHKALYLQKN", "length": 426, "header": "tr|F1NU59-1|F1NU59_CHICK Isoform 1 of Glucosaminyl (N-acetyl) transferase 1 OS=Gallus gallus OX=9031 GN=GCNT1 PE=3 SV=2 CANONICAL=F1NU59-1" }, "isoforms": [ { "isoform_ac": "F1NU59-1", "url": "https://www.uniprot.org/uniprotkb/F1NU59/entry#F1NU59-1", "sequence": { "sequence": "MLKRKLRFFHNSCFRLFLGLTLILVIISVLKVNQKADFLNRRHLDLTKEDPIGDVNCTKILEGDIEEIQKVKLETLSVSFKKRPKLTTSDYINMTTDCSSFTKMRKYIMEPLSSEEAEFPIAYSIVVYHKIEMLDRLLRSIYAPQNFYCIHVDKKSPESFFTAVKGIVSCFDNVFISSQLESVVYASWSRVQADINCMKDLYRRSSNWKYLINLCGMDFPIKTNREIVEKLKALKGENSLETEKMPVYKEVRWKKHYEIVDGKVKNTGIDKQLPPLSTPIFSGSAYFVVSRRFVEYVLENSKILKFIEWAKDTYSPDEYLWATIQRIPDVPGAVSSSDKYDVSDMNALARFVKWQYFEGDVSKGAPYPPCSGIHVRSVCVFGVGDLNWMLRNHHFFANKFDTDVDPFAVKCLEEYLRHKALYLQKN", "length": 426, "header": "tr|F1NU59-1|F1NU59_CHICK Isoform 1 of Glucosaminyl (N-acetyl) transferase 1 OS=Gallus gallus OX=9031 GN=GCNT1 PE=3 SV=2 CANONICAL=F1NU59-1" }, "locus": { "chromosome": "Z", "start_pos": 37981393, "end_pos": 37980116, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010036453.1", "url": "https://www.ensembl.org/id/ENSGALT00010036453.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021213.1", "url": "https://www.ensembl.org/id/ENSGALP00010021213.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:427260", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427260", "resource": "KEGG Pathway" }, { "id": "R-GGA-913709", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-913709", "resource": "Reactome", "description": "O-linked glycosylation of mucins" } ], "orthologs": [ { "uniprot_canonical_ac": "F1MUW5-1", "protein_name": "Glucosaminyl (N-acetyl) transferase 1", "gene_name": "GCNT1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MLRKLWRRKLFSFPTKYYFLFLAFSVVTFTVLRIHQKTEFVNFGHLELFEENPSSNINCTKILQGDVDEIQKVKLESLTVKFKKRARWTNYDYINMTGDCASFIKKRKYITEPLSKEEAGFPIAYSIVVHHKIEMLDRLLRAIYMPQNFYCIHVDAKSEKSFLAAAVGIASCFSNVFVASQLESVVYASWSRVQADLNCMQDLYQMNAGWKYLINLCGMDFPIKTNLEIVRKLKLLMGENNLETEKMPSHKKERWKKHYEVVNGKLTNMGTDKIHPPLETPLFSGSAYFVVSREYVEYVLQNQNIQKFMEWAKDTYSPDEYLWATIQRIPEVPGSLSLSYKYDTSDMQAIARFVKWQYFEGDVSKGAPYPPCSGVHVRSVCVFGAGDLNWLLHVHHLFANKFDTDIDLFAIQCLDEHLRHKALETLKP", "length": 428 }, "evidence": [ { "id": "F1NU59", "url": "https://omabrowser.org/oma/group/F1NU59/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1SIN0-1", "protein_name": "Glucosaminyl (N-acetyl) transferase 1", "gene_name": "GCNT1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MLRKFWKRRLFSYPTKYYFLFFIFSLVTFSVLKIHQKPEFVNIGHLELVEENPSSSINCTKVLQGDVDEIQKVKLEILTVKFRERPRWTAYDYINMTADCPSFIKKRKYITEPLSKEEAEFPIAYSIVVHHKIEMLDRLLRAIYMPQNFYCIHVDKKSEESFLAAVIGIASCFSNVFVASQLESVVYASWSRVQADLNCMQDLYQMNADWKYLINLCGMDFPIKTNLEIVRMLKLLKGGSNLETERMPSNKKERWKKHYTVVNGKLTNMGTDKTHPPLETPLFSGSAYFVVSRSYVEYVLENEKIQKFMEWAKDTYSPDEYLWATIQRIPEVPGSLSLSHKYDMSDMHSIARFVKWQYFEGDVSKGAPYPPCSGIHVRSVCVFGAGDLNWLLRTHHLFANKFDTDIDLFAIQCLDEHLRHKALEALKH", "length": 428 }, "evidence": [ { "id": "F1NU59", "url": "https://omabrowser.org/oma/group/F1NU59/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q02742-1", "protein_name": "Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase", "gene_name": "GCNT1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLRTLLRRRLFSYPTKYYFMVLVLSLITFSVLRIHQKPEFVSVRHLELAGENPSSDINCTKVLQGDVNEIQKVKLEILTVKFKKRPRWTPDDYINMTSDCSSFIKRRKYIVEPLSKEEAEFPIAYSIVVHHKIEMLDRLLRAIYMPQNFYCIHVDTKSEDSYLAAVMGIASCFSNVFVASRLESVVYASWSRVQADLNCMKDLYAMSANWKYLINLCGMDFPIKTNLEIVRKLKLLMGENNLETERMPSHKEERWKKRYEVVNGKLTNTGTVKMLPPLETPLFSGSAYFVVSREYVGYVLQNEKIQKLMEWAQDTYSPDEYLWATIQRIPEVPGSLPASHKYDLSDMQAVARFVKWQYFEGDVSKGAPYPPCDGVHVRSVCIFGAGDLNWMLRKHHLFANKFDVDVDLFAIQCLDEHLRHKALETLKH", "length": 428 }, "evidence": [ { "id": "F1NU59", "url": "https://omabrowser.org/oma/group/F1NU59/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q09324-1", "protein_name": "Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase", "gene_name": "Gcnt1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLRNLFRRRLFSCPTKYYFMLLVLSLITFSVLRIHQKPEFFSVRHLELAGDDPYSNVNCTKILQGDPEEIQKVKLEILTVQFKKRPRRTPHDYINMTRDCASFIRTRKYIVEPLTKEEVGFPIAYSIVVHHKIEMLDRLLRAIYMPQNFYCIHVDRKAEESFLAAVQGIASCFDNVFVASQLESVVYASWSRVKADLNCMKDLYRMNANWKYLINLCGMDFPIKTNLEIVRKLKCSTGENNLETEKMPPNKEERWKKRYTVVDGKLTNTGIVKAPPPLKTPLFSGSAYFVVTREYVGYVLENENIQKLMEWAQDTYSPDEFLWATIQRIPEVPGSFPSSNKYDLSDMNAIARFVKWQYFEGHVSNGAPYPPCSGVHVRSVCVFGAGDLSWMLRQHHLFANKFDMDVDPFAIQCLDEHLRHKALENLEH", "length": 428 }, "evidence": [ { "id": "F1NU59", "url": "https://omabrowser.org/oma/group/F1NU59/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q64165-1", "protein_name": "Glucosaminyl (N-acetyl) transferase 1", "gene_name": "Gcnt1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLRNLFRRRLFSYPTKYYFMVLVLSLITFSVVRIHQKPEFVSVSHLELSGDDPNSNVNCTKVLQGDPEEIQKVKLEILTVQFKKRPRRTPHDYINMTRDCASFIRTRKYIMEPLTKEEVGFPIAYSIVVHHKIDMLDRLLRAIYMPQNFYCIHVDRKAEESFLAAVQGIASCFDNVFVASQLESVVYASWSRVKADLNCMKDLYRMNANWKYLINLCGMDFPIKTNLEIVRKLKSFTGENSLETEKMPPNKEERWKKRYTVVDGKLTNTGVVKAQPPLKTPLFSGSAYFVVTREYVGYVLENKNIQKFMEWAQDTYSPDEFLWATIQRIPEVPGSLPSSHKYDLSDMNAVARFVKWQYFEGDVSNGAPYPPCSGVHVRSVCVFGVGDLSWMLRKHHFFANKFDMDVDPFALQCLEEHLRHKALETLER", "length": 428 }, "evidence": [ { "id": "F1NU59", "url": "https://omabrowser.org/oma/group/F1NU59/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity", "id": "GO:0003829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003829", "evidence": [ { "database": "UniProtKB", "id": "F1NU59", "url": "https://www.uniprot.org/uniprotkb/F1NU59" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "positive regulation of leukocyte tethering or rolling", "id": "GO:1903238", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903238", "evidence": [ { "database": "UniProtKB", "id": "F1NU59", "url": "https://www.uniprot.org/uniprotkb/F1NU59" } ], "pmid": "" }, { "name": "protein O-linked glycosylation via N-acetyl-galactosamine", "id": "GO:0016266", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016266", "evidence": [ { "database": "UniProtKB", "id": "F1NU59", "url": "https://www.uniprot.org/uniprotkb/F1NU59" } ], "pmid": "" }, { "name": "leukocyte tethering or rolling", "id": "GO:0050901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050901", "evidence": [ { "database": "UniProtKB", "id": "F1NU59", "url": "https://www.uniprot.org/uniprotkb/F1NU59" } ], "pmid": "" }, { "name": "cell adhesion molecule production", "id": "GO:0060352", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060352", "evidence": [ { 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"tr|F1NU79-1|F1NU79_CHICK Isoform 1 of 26S proteasome regulatory subunit 8 OS=Gallus gallus OX=9031 GN=PSMC5 PE=1 SV=2 CANONICAL=F1NU79-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A5L5-1", "url": "https://www.uniprot.org/uniprotkb/F1NU79/entry#A0A8V1A5L5-1", "sequence": { "sequence": "MPAEKMAVDGPEQMEMDDGKGGTGLRQYYLSKIEELQLLQEQGSYVGEVVRAMDKKKVLVKVHPEGKFVVDVDKNIDINDVTPNCRVALRNDSYTLHKILPNKVDPLVSLMMVEKVPDSTYEMIGGLDKQIKEIKEVIELPVKHPELFEALGIAQPKGVLLYGPPGTGKTLLARAVAHHTDCTFIRVSGSELVQKFIGEGARMVRELFVMAREHAPSIIFMDEIDSIGSSRLEGGSGGDSEVQRTMLELLNQLDGFEATKNIKVIMATNRIDILDSALLRPGRIDRKIEFPPPNEEARLDILKIHSRKMNLTRGINLRKIAELMPGASGAEVKGVCTEAGMYALRERRVHVTQEDFEMAVAKVMQKDSEKNMSIKKLWK", "length": 379, "header": "tr|A0A8V1A5L5-1|A0A8V1A5L5_CHICK Computationally mapped isoform of Proteasome 26S subunit, ATPase 5 OS=Gallus gallus OX=9031 GN=PSMC5 PE=1 SV=1 CANONICAL=F1NU79-1" }, "locus": { "chromosome": "27", "start_pos": 1356119, "end_pos": 1352708, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010063844.1", "url": "https://www.ensembl.org/id/ENSGALT00010063844.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039357.1", "url": "https://www.ensembl.org/id/ENSGALP00010039357.1" } ] } }, { "isoform_ac": "F1NU79-1", "url": "https://www.uniprot.org/uniprotkb/F1NU79/entry#F1NU79-1", "sequence": { "sequence": "MPAEKMAVDGPEQMEMDDGKGGTGLRQYYLSKIEELQLIVNEKSQNLRRLQAQRNELNAKVRLLREELQLLQEQGSYVGEVVRAMDKKKVLVKVHPEGKFVVDVDKNIDINDVTPNCRVALRNDSYTLHKILPNKVDPLVSLMMVEKVPDSTYEMIGGLDKQIKEIKEVIELPVKHPELFEALGIAQPKGVLLYGPPGTGKTLLARAVAHHTDCTFIRVSGSELVQKFIGEGARMVRELFVMAREHAPSIIFMDEIDSIGSSRLEGGSGGDSEVQRTMLELLNQLDGFEATKNIKVIMATNRIDILDSALLRPGRIDRKIEFPPPNEEARLDILKIHSRKMNLTRGINLRKIAELMPGASGAEVKGVCTEAGMYALRERRVHVTQEDFEMAVAKVMQKDSEKNMSIKKLWK", "length": 411, "header": "tr|F1NU79-1|F1NU79_CHICK Isoform 1 of 26S proteasome regulatory subunit 8 OS=Gallus gallus OX=9031 GN=PSMC5 PE=1 SV=2 CANONICAL=F1NU79-1" }, "locus": { "chromosome": "27", "start_pos": 1356119, "end_pos": 1352708, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010063841.1", "url": "https://www.ensembl.org/id/ENSGALT00010063841.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039355.1", "url": "https://www.ensembl.org/id/ENSGALP00010039355.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:428274", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:428274", "resource": "KEGG Pathway" }, { "id": "R-GGA-1169091", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1169091", "resource": "Reactome", "description": "Activation of NF-kappaB in B cells" }, { "id": "R-GGA-1234176", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1234176", "resource": "Reactome", "description": "Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha" }, { "id": "R-GGA-1236978", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1236978", "resource": "Reactome", "description": "Cross-presentation of soluble exogenous antigens (endosomes)" }, { "id": "R-GGA-174084", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-174084", "resource": "Reactome", "description": "Autodegradation of Cdh1 by Cdh1:APC/C" }, { "id": "R-GGA-174154", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-174154", "resource": "Reactome", "description": "APC/C:Cdc20 mediated degradation of Securin" }, { "id": "R-GGA-174178", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-174178", "resource": "Reactome", "description": "APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1" }, { "id": "R-GGA-174184", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-174184", "resource": "Reactome", "description": "Cdc20:Phospho-APC/C mediated degradation of Cyclin A" }, { "id": "R-GGA-187577", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-187577", "resource": "Reactome", "description": "SCF(Skp2)-mediated degradation of p27/p21" }, { "id": "R-GGA-195253", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-195253", "resource": "Reactome", "description": "Degradation of beta-catenin by the destruction complex" }, { "id": "R-GGA-202424", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-202424", "resource": "Reactome", "description": "Downstream TCR signaling" }, { "id": "R-GGA-2467813", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2467813", "resource": "Reactome", "description": "Separation of Sister Chromatids" }, { "id": "R-GGA-2871837", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2871837", "resource": "Reactome", "description": "FCERI mediated NF-kB activation" }, { "id": "R-GGA-349425", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-349425", "resource": "Reactome", "description": "Autodegradation of the E3 ubiquitin ligase COP1" }, { "id": "R-GGA-350562", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-350562", "resource": "Reactome", "description": "Regulation of ornithine decarboxylase (ODC)" }, { "id": "R-GGA-382556", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-382556", "resource": "Reactome", "description": "ABC-family protein mediated transport" }, { "id": "R-GGA-450408", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-450408", "resource": "Reactome", "description": "AUF1 (hnRNP D0) binds and destabilizes mRNA" }, { "id": "R-GGA-4608870", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-4608870", "resource": "Reactome", "description": "Asymmetric localization of PCP proteins" }, { "id": "R-GGA-4641257", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-4641257", "resource": "Reactome", "description": "Degradation of AXIN" }, { "id": "R-GGA-4641258", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-4641258", "resource": "Reactome", "description": "Degradation of DVL" }, { "id": "R-GGA-5358346", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5358346", "resource": "Reactome", "description": "Hedgehog ligand biogenesis" }, { "id": "R-GGA-5607764", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5607764", "resource": "Reactome", "description": "CLEC7A (Dectin-1) signaling" }, { "id": "R-GGA-5610780", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5610780", "resource": "Reactome", "description": "Degradation of GLI1 by the proteasome" }, { "id": "R-GGA-5610785", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5610785", "resource": "Reactome", "description": "GLI3 is processed to GLI3R by the proteasome" }, { "id": "R-GGA-5632684", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5632684", "resource": "Reactome", "description": "Hedgehog 'on' state" }, { "id": "R-GGA-5658442", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5658442", "resource": "Reactome", "description": "Regulation of RAS by GAPs" }, { "id": "R-GGA-5668541", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5668541", "resource": "Reactome", "description": "TNFR2 non-canonical NF-kB pathway" }, { "id": "R-GGA-5687128", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5687128", "resource": "Reactome", "description": "MAPK6/MAPK4 signaling" }, { "id": "R-GGA-5689603", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5689603", "resource": "Reactome", "description": "UCH proteinases" }, { "id": "R-GGA-5689880", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5689880", "resource": "Reactome", "description": "Ub-specific processing proteases" }, { "id": "R-GGA-68867", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-68867", "resource": "Reactome", "description": "Assembly of the pre-replicative complex" }, { "id": "R-GGA-68949", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-68949", "resource": "Reactome", "description": "Orc1 removal from chromatin" }, { "id": "R-GGA-69017", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-69017", "resource": "Reactome", "description": "CDK-mediated phosphorylation and removal of Cdc6" }, { "id": "R-GGA-69601", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-69601", "resource": "Reactome", "description": "Ubiquitin-Mediated Degradation of Phosphorylated Cdc25A" }, { "id": "R-GGA-75815", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-75815", "resource": "Reactome", "description": "Ubiquitin-dependent degradation of Cyclin D" }, { "id": "R-GGA-8854050", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8854050", "resource": "Reactome", "description": "FBXL7 down-regulates AURKA during mitotic entry and in early mitosis" }, { "id": "R-GGA-8939236", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8939236", "resource": "Reactome", "description": "RUNX1 regulates transcription of genes involved in differentiation of HSCs" }, { "id": "R-GGA-8939902", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8939902", "resource": "Reactome", "description": "Regulation of RUNX2 expression and activity" }, { "id": "R-GGA-8941858", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8941858", "resource": "Reactome", "description": "Regulation of RUNX3 expression and activity" }, { "id": "R-GGA-8948751", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8948751", "resource": "Reactome", "description": "Regulation of PTEN stability and activity" }, { "id": "R-GGA-8951664", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8951664", "resource": "Reactome", "description": "Neddylation" }, { "id": "R-GGA-9020702", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9020702", "resource": "Reactome", "description": "Interleukin-1 signaling" }, { "id": "R-GGA-9755511", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9755511", "resource": "Reactome", "description": "KEAP1-NFE2L2 pathway" }, { "id": "R-GGA-9762114", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9762114", "resource": "Reactome", "description": "GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2" }, { "id": "R-GGA-9766229", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9766229", "resource": "Reactome", "description": "Degradation of CDH1" }, { "id": "R-GGA-983168", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983168", "resource": "Reactome", "description": "Antigen processing: Ubiquitination & Proteasome degradation" }, { "id": "R-GGA-9907900", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9907900", "resource": "Reactome", "description": "Proteasome assembly" }, { "id": "R-GGA-9929356", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9929356", "resource": "Reactome", "description": "GSK3B-mediated proteasomal degradation of PD-L1(CD274)" }, { "id": "R-GGA-9929491", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9929491", "resource": "Reactome", "description": "SPOP-mediated proteasomal degradation of PD-L1(CD274)" }, { "id": "R-GGA-9931269", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9931269", "resource": "Reactome", "description": "AMPK-induced ERAD and lysosome mediated degradation of PD-L1(CD274)" }, { "id": "R-GGA-9932298", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9932298", "resource": "Reactome", "description": "Degradation of CRY and PER proteins" }, { "id": "R-GGA-9954709", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9954709", "resource": "Reactome", "description": "Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide" } ], "orthologs": [ { "uniprot_canonical_ac": "O18413-1", "protein_name": "26S proteasome regulatory subunit 8", "gene_name": "Rpt6", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MTVTNRMEIESAYHKGEGFRSYYIQKIEELQLVVAEKHQNLRRLQAQRNELNAKVRMLREELQLLQEQGSYVGEVVKPMDKKKVLVKVHPEGKFVVDLDKNIDINDVTPNCRVALRNESYTLHKILPNKVDPLVSLMMVEKVPDSTYEMVGGLDKQIKEIKEVIELPVKHPELFDALGIAQPKGVLLYGPPGTGKTLLARAVAHHTECTFIRVSGSELVQKFIGEGSRMVRELFVMAREHAPSIIFMDEIDSIGSSRIESGSGGDSEVQRTMLELLNQLDGFEATKNIKVIMATNRIDILDPALLRPGRIDRKIEFPPPNEEARLDILKIHSRKMNLTRGINLRKIAELMPGASGAEVKGVCTEAGMYALRERRVHVTQEDFEMAVAKVMQKDSEKNMSIKKLWK", "length": 405 }, "evidence": [ { "id": "F1NU79", "url": "https://omabrowser.org/oma/group/F1NU79/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "P34124-1", "protein_name": "26S proteasome regulatory subunit 8", "gene_name": "psmC5", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MVAQNNQQNKDETKGIKSYYCSKIEELEIKVNEKAQDLRRLEAQRNELNNRVRMLKEELQLLTNPGSHVAEVVKLMGKNKVLVKVNPEGKFVVDIDPTVDIAKLTPSTRAALKHESYTLHRILPNKIDPLVSLMKVEKIPDSTYDMVGGLDKQIKEIKEVIELPIKHPELFESLGIAQPKGVLLYGPPGTGKTLLARAVAHHTDCTFIRVSGSELVQKYIGEGSRMVRELFIMAREHAPSIIFMDEIDSIGSSRGESGSGGGDSEVQRTMLELLNQLDGFESTKNIKVLMCTNRIDILDPALLRPGRIDRKIEFPNPGDAGRLDILKIHSRKMNLTRGINLKKISDKMNGASGAELKAVCTEAGMYALRERRVHVSQEDFEMAVSKVMKKDSEQNMSINKLWK", "length": 403 }, "evidence": [ { "id": "F1NU79", "url": "https://omabrowser.org/oma/group/F1NU79/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "P62194-1", "protein_name": "26S proteasome regulatory subunit 8", "gene_name": "PSMC5", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MALDGPEQMELEEGKAGSGLRQYYLSKIEELQLIVNDKSQNLRRLQAQRNELNAKVRLLREELQLLQEQGSYVGEVVRAMDKKKVLVKVHPEGKFVVDVDKNIDINDVTPNCRVALRNDSYTLHKILPNKVDPLVSLMMVEKVPDSTYEMIGGLDKQIKEIKEVIELPVKHPELFEALGIAQPKGVLLYGPPGTGKTLLARAVAHHTDCTFIRVSGSELVQKFIGEGARMVRELFVMAREHAPSIIFMDEIDSIGSSRLEGGSGGDSEVQRTMLELLNQLDGFEATKNIKVIMATNRIDILDSALLRPGRIDRKIEFPPPNEEARLDILKIHSRKMNLTRGINLRKIAELMPGASGAEVKGVCTEAGMYALRERRVHVTQEDFEMAVAKVMQKDSEKNMSIKKLWK", "length": 406 }, "evidence": [ { "id": "F1NU79", "url": "https://omabrowser.org/oma/group/F1NU79/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P62195-1", "protein_name": "26S proteasome regulatory subunit 8", "gene_name": "PSMC5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MALDGPEQMELEEGKAGSGLRQYYLSKIEELQLIVNDKSQNLRRLQAQRNELNAKVRLLREELQLLQEQGSYVGEVVRAMDKKKVLVKVHPEGKFVVDVDKNIDINDVTPNCRVALRNDSYTLHKILPNKVDPLVSLMMVEKVPDSTYEMIGGLDKQIKEIKEVIELPVKHPELFEALGIAQPKGVLLYGPPGTGKTLLARAVAHHTDCTFIRVSGSELVQKFIGEGARMVRELFVMAREHAPSIIFMDEIDSIGSSRLEGGSGGDSEVQRTMLELLNQLDGFEATKNIKVIMATNRIDILDSALLRPGRIDRKIEFPPPNEEARLDILKIHSRKMNLTRGINLRKIAELMPGASGAEVKGVCTEAGMYALRERRVHVTQEDFEMAVAKVMQKDSEKNMSIKKLWK", "length": 406 }, "evidence": [ { "id": "F1NU79", "url": "https://omabrowser.org/oma/group/F1NU79/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P62196-1", "protein_name": "26S proteasome regulatory subunit 8", "gene_name": "Psmc5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALDGPEQMELEEGKAGSGLRQYYLSKIEELQLIVNDKSQNLRRLQAQRNELNAKVRLLREELQLLQEQGSYVGEVVRAMDKKKVLVKVHPEGKFVVDVDKNIDINDVTPNCRVALRNDSYTLHKILPNKVDPLVSLMMVEKVPDSTYEMIGGLDKQIKEIKEVIELPVKHPELFEALGIAQPKGVLLYGPPGTGKTLLARAVAHHTDCTFIRVSGSELVQKFIGEGARMVRELFVMAREHAPSIIFMDEIDSIGSSRLEGGSGGDSEVQRTMLELLNQLDGFEATKNIKVIMATNRIDILDSALLRPGRIDRKIEFPPPNEEARLDILKIHSRKMNLTRGINLRKIAELMPGASGAEVKGVCTEAGMYALRERRVHVTQEDFEMAVAKVMQKDSEKNMSIKKLWK", "length": 406 }, "evidence": [ { "id": "F1NU79", "url": "https://omabrowser.org/oma/group/F1NU79/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P62198-1", "protein_name": "26S proteasome regulatory subunit 8", "gene_name": "Psmc5", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MALDGPEQMELEEGKAGSGLRQYYLSKIEELQLIVNDKSQNLRRLQAQRNELNAKVRLLREELQLLQEQGSYVGEVVRAMDKKKVLVKVHPEGKFVVDVDKNIDINDVTPNCRVALRNDSYTLHKILPNKVDPLVSLMMVEKVPDSTYEMIGGLDKQIKEIKEVIELPVKHPELFEALGIAQPKGVLLYGPPGTGKTLLARAVAHHTDCTFIRVSGSELVQKFIGEGARMVRELFVMAREHAPSIIFMDEIDSIGSSRLEGGSGGDSEVQRTMLELLNQLDGFEATKNIKVIMATNRIDILDSALLRPGRIDRKIEFPPPNEEARLDILKIHSRKMNLTRGINLRKIAELMPGASGAEVKGVCTEAGMYALRERRVHVTQEDFEMAVAKVMQKDSEKNMSIKKLWK", "length": 406 }, "evidence": [ { "id": "F1NU79", "url": "https://omabrowser.org/oma/group/F1NU79/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q01939-1", "protein_name": "26S proteasome regulatory subunit 8 homolog", "gene_name": "RPT6", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MTAAVTSSNIVLETHESGIKPYFEQKIQETELKIRSKTENVRRLEAQRNALNDKVRFIKDELRLLQEPGSYVGEVIKIVSDKKVLVKVQPEGKYIVDVAKDINVKDLKASQRVCLRSDSYMLHKVLENKADPLVSLMMVEKVPDSTYDMVGGLTKQIKEIKEVIELPVKHPELFESLGIAQPKGVILYGPPGTGKTLLARAVAHHTDCKFIRVSGAELVQKYIGEGSRMVRELFVMAREHAPSIIFMDEIDSIGSTRVEGSGGGDSEVQRTMLELLNQLDGFETSKNIKIIMATNRLDILDPALLRPGRIDRKIEFPPPSVAARAEILRIHSRKMNLTRGINLRKVAEKMNGCSGADVKGVCTEAGMYALRERRIHVTQEDFELAVGKVMNKNQETAISVAKLFK", "length": 405 }, "evidence": [ { "id": "F1NU79", "url": "https://omabrowser.org/oma/group/F1NU79/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q9C5U3-1", "protein_name": "26S proteasome regulatory subunit 8 homolog A", "gene_name": "RPT6A", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MAAVGVDSRRPETAMEETCNVKGAAAKQGEGLKQYYLQHIHELQRQLRQKTNNLNRLEAQRNELNSRVRMLREELQLLQEPGSYVGEVVKVMGKNKVLVKVHPEGKYVVDIDKSIDITKITPSTRVALRNDSYVLHLVLPSKVDPLVNLMKVEKVPDSTYDMIGGLDQQIKEIKEVIELPIKHPELFESLGIAQPKGVLLYGPPGTGKTLLARAVAHHTDCTFIRVSGSELVQKYIGEGSRMVRELFVMAREHAPSIIFMDEIDSIGSARMESGSGNGDSEVQRTMLELLNQLDGFEASNKIKVLMATNRIDILDQALLRPGRIDRKIEFPNPNEESRFDILKIHSRKMNLMRGIDLKKIAEKMNGASGAELKAVCTEAGMFALRERRVHVTQEDFEMAVAKVMKKDTEKNMSLRKLWK", "length": 419 }, "evidence": [ { "id": "F1NU79", "url": "https://omabrowser.org/oma/group/F1NU79/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 7, "go_terms": [ { "name": "proteasome regulatory particle, base subcomplex", "id": "GO:0008540", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008540", "evidence": [ { "database": "UniProtKB", "id": "F1NU79", "url": "https://www.uniprot.org/uniprotkb/F1NU79" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1NU79", "url": "https://www.uniprot.org/uniprotkb/F1NU79" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F1NU79", "url": "https://www.uniprot.org/uniprotkb/F1NU79" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F1NU79", "url": "https://www.uniprot.org/uniprotkb/F1NU79" } ], "pmid": "" }, { "name": "cytoplasmic vesicle", "id": "GO:0031410", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031410", "evidence": [ { "database": "UniProtKB", "id": "F1NU79", "url": "https://www.uniprot.org/uniprotkb/F1NU79" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1NU79", "url": "https://www.uniprot.org/uniprotkb/F1NU79" } ], "pmid": "" }, { "name": "proteasome complex", "id": "GO:0000502", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000502", "evidence": [ { "database": "UniProtKB", "id": "F1NU79", "url": "https://www.uniprot.org/uniprotkb/F1NU79" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 6, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "F1NU79", "url": "https://www.uniprot.org/uniprotkb/F1NU79" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "F1NU79", "url": "https://www.uniprot.org/uniprotkb/F1NU79" } ], "pmid": "" }, { "name": "general transcription initiation factor binding", "id": "GO:0140296", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140296", "evidence": [ { "database": "UniProtKB", "id": "F1NU79", "url": "https://www.uniprot.org/uniprotkb/F1NU79" } ], "pmid": "" }, { "name": "proteasome-activating activity", "id": "GO:0036402", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036402", "evidence": [ { "database": "UniProtKB", "id": "F1NU79", "url": "https://www.uniprot.org/uniprotkb/F1NU79" } ], "pmid": "" }, { "name": "thyrotropin-releasing hormone receptor binding", "id": "GO:0031531", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031531", "evidence": [ { "database": "UniProtKB", "id": "F1NU79", "url": "https://www.uniprot.org/uniprotkb/F1NU79" } ], "pmid": "" }, { "name": "DNA-binding transcription factor binding", "id": "GO:0140297", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140297", "evidence": [ { "database": "UniProtKB", "id": "F1NU79", "url": "https://www.uniprot.org/uniprotkb/F1NU79" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "F1NU79", "url": "https://www.uniprot.org/uniprotkb/F1NU79" } ], "pmid": "" }, { "name": "proteasome-mediated ubiquitin-dependent protein catabolic process", "id": "GO:0043161", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043161", "evidence": [ { "database": "UniProtKB", "id": "F1NU79", "url": "https://www.uniprot.org/uniprotkb/F1NU79" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 123, "end_pos": 125, "annotation": "n_glycosylation_sequon" }, { "start_pos": 342, "end_pos": 344, "annotation": "n_glycosylation_sequon" }, { "start_pos": 403, "end_pos": 405, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1NU79-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 411, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1NU79-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1NU79" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1NU79", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NU79" }, { "id": "SM00382", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00382" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "AAA+ ATPase", "eco_id": "ECO_0000259", "start_pos": 187, "end_pos": 326, "start_aa": "Gln", "end_aa": "Asn", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 123, "end_pos": 125 }, { "start_pos": 342, "end_pos": 344 }, { "start_pos": 403, "end_pos": 405 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1NUG3-1", "uniprot_ac": "F1NUG3", "uniprot_id": "F1NUG3_CHICK", "mass": { "chemical_mass": 85385.0, "monoisotopic_mass": 85385.0 }, "refseq": { "ac": "XP_003640531", "name": "synaptotagmin-like protein 5 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003640531" }, "gene_names": [ { "name": "SYTL5", "type": "recommended", "evidence": [ { "id": "F1NUG3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NUG3" } ] }, { "name": "SYTL5", "type": "synonym", "evidence": [ { "id": "XP_003640531", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003640531" } ] } ], "protein_names": [ { "name": "Synaptotagmin-like protein 5", "type": "recommended", "evidence": [ { "id": "F1NUG3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NUG3/entry#names_and_taxonomy" } ] }, { "name": "synaptotagmin-like protein 5 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_003640531", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003640531" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003640531", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003640531" } ] }, { "annotation": "May act as Rab effector protein and play a role in vesicle trafficking. Binds phospholipids.", "evidence": [ { "database": "UniProtKB", "id": "R4GGW7", "url": "https://www.uniprot.org/uniprotkb/R4GGW7#function" }, { "database": "UniProtKB", "id": "ARBA00053749", "url": "https://www.uniprot.org/uniprotkb/ARBA00053749#function" }, { "database": "UniProtKB", "id": "F1NUG3", "url": "https://www.uniprot.org/uniprotkb/F1NUG3#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NUG3", "url": "https://www.uniprot.org/uniprotkb/F1NUG3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SYTL5", "url": "https://www.uniprot.org/uniprotkb/F1NUG3", "locus": { "chromosome": "1", "start_pos": 113145505, "end_pos": 113218923, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010002935", "url": "https://www.ensembl.org/id/ENSGALG00010002935" } ] } } ], "crossref": [ { "id": "F1NUG3", "url": "https://alphafold.ebi.ac.uk/entry/F1NUG3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000016258", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000016258", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd04020", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04020", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd04029", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04029", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "427990", "url": "https://www.ncbi.nlm.nih.gov/gene/427990", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000008", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000008", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR010911", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010911", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011011", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011011", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035892", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035892", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037303", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037303", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041282", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041282", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043567", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043567", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:427990", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427990", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "VEDKRIX", "url": "https://omabrowser.org/oma/group/VEDKRIX/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1NUG3", "url": "https://www.orthodb.org/?gene=F1NUG3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "R4GGW7", "url": "https://www.orthodb.org/?gene=R4GGW7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45716", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45716", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45716:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45716:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00168", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00168", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02318", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02318", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003640531", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003640531", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1NUG3", "url": "https://www.uniprot.org/uniprotkb/F1NUG3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NUG3-1", "url": "https://www.uniprot.org/uniprotkb/F1NUG3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "R4GGW7", "url": "https://www.uniprot.org/uniprotkb/R4GGW7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "R4GGW7-1", "url": "https://www.uniprot.org/uniprotkb/R4GGW7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAKHLEIINLSFLLEHEREMILGVLKRDEYLKKVEDKRIRKLKNELLEVKRKGGSRHCQQDNSRVCVRCQKGLGFIFDRGDLCQTCKLRVCNKCRAVGTDGQWKCSVCAKIAQLRIVTGEWFFEERAKRFKQSNLGTDVVRQSILRKSPDTISSKDEERTFKDQHQENEEKGISTSSITGHKSIFGGPRKIGKIIRAATKGEIAIAKDEGGRSIGSEAESQSLCSSKSTPCSERGSTLSLNSSDTEAAAGHLRGAVGPANRSTASIASLPRSPALSTRSMTVDYSRDADSENGMIIPASESVPEDLVKKHRRKASGTPSIAVSRVSLSSDRSRSEIDLSESFSEGKQDTLSIRSKSVPSTLDEELDYLDETEEDIDDIVASRYSRKRGHLTSGLSRNFPEGSDRKWNYLNVPETDGDTTSINSMLSVYSETGDYSNVKVSGEILLQINYSYKTGALNILVKSCRNLAIVDEKKQRTDPYVKAYLLPDKSRQSKRKTKIKSNSTNPEFNETLKYVISHTQLETRTLQLSVWHYDRFGRNSFLGEVEIPFDSWNFENQGDEWFVLQPKVEVATDVGLQYKGELTVVLRYIPPEINLMLPLGQFQGKKSFKKGKKGENHLPSGGILEVVIKEAKNLTAVKSGGTSDTFVKGYLLPDDNKATKHKTPIVKKNVNPQWNHTFAFSGLNSRDIRNVCLELTVWDKESLSSNIFLGGVRLSTGSGVSNGKEVDWMDSQGEEQHLWQKMIDSPGTSVEGILMLRSSMGKRRH", "length": 764, "header": "tr|F1NUG3-1|F1NUG3_CHICK Isoform 1 of Synaptotagmin-like protein 5 OS=Gallus gallus OX=9031 GN=SYTL5 PE=4 SV=5 CANONICAL=F1NUG3-1" }, "isoforms": [ { "isoform_ac": "F1NUG3-1", "url": "https://www.uniprot.org/uniprotkb/F1NUG3/entry#F1NUG3-1", "sequence": { "sequence": "MAKHLEIINLSFLLEHEREMILGVLKRDEYLKKVEDKRIRKLKNELLEVKRKGGSRHCQQDNSRVCVRCQKGLGFIFDRGDLCQTCKLRVCNKCRAVGTDGQWKCSVCAKIAQLRIVTGEWFFEERAKRFKQSNLGTDVVRQSILRKSPDTISSKDEERTFKDQHQENEEKGISTSSITGHKSIFGGPRKIGKIIRAATKGEIAIAKDEGGRSIGSEAESQSLCSSKSTPCSERGSTLSLNSSDTEAAAGHLRGAVGPANRSTASIASLPRSPALSTRSMTVDYSRDADSENGMIIPASESVPEDLVKKHRRKASGTPSIAVSRVSLSSDRSRSEIDLSESFSEGKQDTLSIRSKSVPSTLDEELDYLDETEEDIDDIVASRYSRKRGHLTSGLSRNFPEGSDRKWNYLNVPETDGDTTSINSMLSVYSETGDYSNVKVSGEILLQINYSYKTGALNILVKSCRNLAIVDEKKQRTDPYVKAYLLPDKSRQSKRKTKIKSNSTNPEFNETLKYVISHTQLETRTLQLSVWHYDRFGRNSFLGEVEIPFDSWNFENQGDEWFVLQPKVEVATDVGLQYKGELTVVLRYIPPEINLMLPLGQFQGKKSFKKGKKGENHLPSGGILEVVIKEAKNLTAVKSGGTSDTFVKGYLLPDDNKATKHKTPIVKKNVNPQWNHTFAFSGLNSRDIRNVCLELTVWDKESLSSNIFLGGVRLSTGSGVSNGKEVDWMDSQGEEQHLWQKMIDSPGTSVEGILMLRSSMGKRRH", "length": 764, "header": "tr|F1NUG3-1|F1NUG3_CHICK Isoform 1 of Synaptotagmin-like protein 5 OS=Gallus gallus OX=9031 GN=SYTL5 PE=4 SV=5 CANONICAL=F1NUG3-1" }, "locus": { "chromosome": "1", "start_pos": 113190686, "end_pos": 113146509, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010006831.1", "url": "https://www.ensembl.org/id/ENSGALT00010006831.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010004164.1", "url": "https://www.ensembl.org/id/ENSGALP00010004164.1" } ] } }, { "isoform_ac": "R4GGW7-1", "url": "https://www.uniprot.org/uniprotkb/F1NUG3/entry#R4GGW7-1", "sequence": { "sequence": "MAKHLEIINLSFLLEHEREMILGVLKRDEYLKKVEDKRIRKLKNELLEVKRKGGSRHCQQDNSRVCVRCQKGLGFIFDRGDLCQTCKLRVCNKCRAVGTDGQWKCSVCAKIAQLRIVTGEWFFEERAKRFKQSNLGTDVVRQSILRKSPDTISSKDEERTFKDQHQENEEKGISTSSITGHKSIFGGPRKIGKIIRAATKGEIAIAKDEGGRSIGSEAESQSLCSSKSTPCSERGSTLSLNSSDTEAAAGHLRGAVGPANRSTASIASLPRSPALSTRSMTVDYSRDADSENGMIIPASESVPEDLVKKHRRKASGTPSIAVSRVSLSSDRSRSEIDLSESFSEGKQDTLSIRSKSVPSTLDEELDYLDETEEDIDDIVASRYSRKRGHLTSGLSRTSINSMLSVYSETGDYSNVKVSGEILLQINYSYKTGALNILVKSCRNLAIVDEKKQRTDPYVKAYLLPDKSRQSKRKTKIKSNSTNPEFNETLKYVISHTQLETRTLQLSVWHYDRFGRNSFLGEVEIPFDSWNFENQGDEWFVLQPKVEVATDVGLQYKGELTVVLRYIPPEINLMLPLGQFQGKKSFKKGKKGENHLPSGGILEVVIKEAKNLTAVKSGGTSDTFVKGYLLPDDNKATKHKTPIVKKNVNPQWNHTFAFSGLNSRDIRNVCLELTVWDKESLSSNIFLGGVRLSTGSGVSNGKEVDWMDSQGEEQHLWQKMIDSPGTSVEGILMLRSSMGKRRH", "length": 742, "header": "tr|R4GGW7-1|R4GGW7_CHICK Computationally mapped isoform of Synaptotagmin-like protein 5 OS=Gallus gallus OX=9031 GN=SYTL5 PE=4 SV=4 CANONICAL=F1NUG3-1" }, "locus": { "chromosome": "1", "start_pos": 113190686, "end_pos": 113146509, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010006854.1", "url": "https://www.ensembl.org/id/ENSGALT00010006854.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010004176.1", "url": "https://www.ensembl.org/id/ENSGALP00010004176.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 317, "start_aa": "Thr", "end_pos": 317, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr317", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:427990", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427990", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8N7TAN5-1", "protein_name": "Synaptotagmin-like protein 5", "gene_name": "sytl5", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MVMAKKTESLNLSFLLEHERQMILNVLQKDEKLRKREEKRIRKLKNELLELKRAGRRSSADQRECAICLRALGLILQRGNVCSNCQRRICNFCTATPTGSSCKCTVCAKTAELKVVTGEWFLEERSKRFQSATVPSCDVVKQSILSSPPDGGSANRPLEMERSSTPKSERSVTPQSQKSTGKNRKGKRAVAVEPSGLPTVPNNMRAQMAKTPTQTEARNRPDGAESVSSIQSSDSVPEKMADGRRQTDSSTPSIAVSRASLSSDRSRSEVDLSNPGEGLSEDPLISRCRSVPGLNDGDSDEDIDAVLSAHYKTNRSVCSAQSMSSTPASERKWGFLNVPDSDADTTSINSLMSVYSETGDYGSVRVSGEILLNISYSYKTGALNVLVRECRCLATGDERRQRTDAYVKTYLLPDKSRQSKRKTSIKSNSTNPVFNENLRYVVSHSQLETRTLQVSVWHHDRFGHNNFLGETELTFDSWEFDTQIEEWFALQPRIESDYVDSVMHYKGELTVVLKYIPAERNVSLPLDQVQVKKGFLKGKKKTITLPKGGMVELLVKEAKNLTAVKGGSSDPFVKGYLLPDDKKSTKHKTAVVKRSVNPRWNHTFTYCGLQHSDLDSVCLELTVWDREPFASNVFLGGVRLGAGTGLSYGKEVDWNDAYGEEQRLWQRMIDNPEVPQECTLMLRSSMARRKTD", "length": 692 }, "evidence": [ { "id": "F1NUG3", "url": "https://omabrowser.org/oma/group/F1NUG3/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1RXS2-1", "protein_name": "Synaptotagmin-like protein 5", "gene_name": "SYTL5", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSKNSEFINLSFLLDHEKEMILGVLKRDEYLKKVEDKRIRKLKNELLEAKRRSGKIQQETSRVCAHCQRNLGLIFDRGDPCPACSLRVCAQCRVSSLDGSWRCIICAKVAQLRTVTGEWFFEEKAKRFKQVNVLGTDVVRQSILRRSPAEETQSQEQTRQKAEKSDTSPSAGHKTSHDGPRKRGFLLSKFRSATRGEIITPKAESGRSYSLDLDSQNFRSLRSAPGSDRGSTGSSDLNEQEAASGTPKSIRSNGVTPVSQRSPAPSTRSATSGSSRKEHGFENSMDLAATESTSEDLPKRHRRKTSGTPSIAVSRASLSSDRSQSELDLSGSFTEDLEDPVNIRSKSVSGALDKDLDSLEETEEVIDDLVSSRFSANTHSLASGLSTNSPAGSDRKWTYLSVPDADSDTTSLNSMMSVYSETGDYGNVKVSGEILLHISYCYKTGGLYIFVKNCRNLAIGDEKKQRTDAYVKSYLLPDKSRNNKRKTKIRTGTNPEFNETLKYTISHTQLETRTLQLSVWHHDRFGRNSFLGEVEIPFDSWNFENPSDEWFVLQPKVEYAADTGLQYKGELTVVLRYIPPEENMALPLEQLQGKKTFKRGKKKDAPISSGGILEVFVKEAKNLTAVKSGGTSDSFVKGYLLPDDNKATKHKTLVIKKSVNPQWNHTFMFSGLHPQDIKDVCLELTVWDKEAFSSNIFLGGVRLNSGSGVSRGKSADWMDAQGEEQRLWQKMADNPGTAVEGVLMLRASMGKRKL", "length": 754 }, "evidence": [ { "id": "F1NUG3", "url": "https://omabrowser.org/oma/group/F1NUG3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q80T23-1", "protein_name": "Synaptotagmin-like protein 5", "gene_name": "Sytl5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSKNSEFINLSFLLDHEKEMILGVLKRDEYLKKVEDKRIRKLKNELLEAKRRSGKTHQEASRVCVHCHKTLGLIFDRGDPCQACSLRVCSECRVTGLDGSWKCTVCAKVAQLRIISGEWFLEEKAKRFKQVNVLGTDVVRQSILRRSPGSEETQNQEQAQQCVDKSDTLSSVRQKTTHDGPKKKGFLLSKFRSATRGEIRTPKPESGRSYSLDLDSQNLQSFKSASGSDRGSTTSSDLIDQEAGRRTSKSSYSNGGIPVTQRSPVPSAHSVTSINSREHGFENSMALATIENTCEELTKSHRRNTSGTPSIAVSGTSLSSERSRSEVDLSESFAEDLEDTSSIRSRSVPGALDKDLNSLEDTEDGVDLVSSRFSANTHSLASGLSTNSQAGSDRKRSYLNVPDADSDTTSLNSMMSVYSETGDYGNVKVTGEILLHISYCYKTGGLYIFVKSCRNLATGDEKKQRTDAYVKSYLLPDKSRNNKRKTKIRTGTNPEFNETLKYTISHTQLETRTLQLSVWHYDRFGRNSFLGEVEIAFDSWNFENPCDEWFVLQPKVELAPDISLQYKGELTIVLRYIPPEENLIFPAGQRQEKKIFKRGKKKESSSISGGILEVFIKKAKNLTAVKSGGTSDSFVKGYLLPDDNKATKHKTAVVKKSVNPEWNHTFIFSGLYPQDIKNACLELTIWDKEAFSSNVFLGGVRLNSGSGMSYGKTVDWMDSHGEEQRLWQKMADNPGTSVEGVLMLRSSMAKCRL", "length": 753 }, "evidence": [ { "id": "F1NUG3", "url": "https://omabrowser.org/oma/group/F1NUG3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q812E4-1", "protein_name": "Synaptotagmin-like protein 5", "gene_name": "Sytl5", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSKNSEFINLSFLLDHEKEMILGVLKRDEYLKKVEDKRIRKLKNELLEAKRRSGKTHQEANRVCVHCQKSLGLIFDRGAPCQACSLRVCSECRVTGLDGSWKCTVCAKVAQLRIISGEWFLEEKAKRFKQVNVLGTDVVRQSILRRSPGSEEIQNQEQAHQGADKSDTLSSVRQKATHDGPKRKGFLLSKFRSATRGEIKTPKAESGRSYSLDLDNQNLQSFKSVSGSDRGSTTSSDLTDQEAGRGAPKGSCSNGGIPVTQRSPAPSARSVTSISSREHGFENSMALATIESISEELTKSHRRNTSGTPSIAVSGTSLSSERSRSELDLSESFAEDLEDTSSIRSRSVPGALDKDLNSLEDTEDGVDLVSSRFSANTHSLASGLSTSSQAGSDRKRSYLHVPDADSDTTSLNSMMSVYSETGDYGNVKVTGEILLHISYCYKTGGLYIFVKNCRNLAIGDEKKQRTDAYVKSYLLPDKTRNNKRKTKIRTGTNPEFNETLKYTISHTQLETRTLQLSVWHYDRFGRNSFLGEVEIAFDSWNFENPCDEWFVLQPKVELAPDISLQYKGELTIVLRYIPPEENLIFPVEQPQGKKIFKKGKKKESPAISGGILEVFIKEAKNLTAVKAGGTSDSFVKGYLLPDDNKATKHKTAVVKKSVNPQWNHVFIFSGLYPQDIQNACLELTIWDKEAFSSNIFLGGVRLNSGSGISHGKAVDWMDSRGEEQRLWQKMADNPGTSVEGVLMLRSSMAKCRL", "length": 753 }, "evidence": [ { "id": "F1NUG3", "url": "https://omabrowser.org/oma/group/F1NUG3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8TDW5-1", "protein_name": "Synaptotagmin-like protein 5", "gene_name": "SYTL5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSKNSEFINLSFLLDHEKEMILGVLKRDEYLKKVEDKRIRKLKNELLEAKRRSGKTQQEASRVCVHCHRNLGLIFDRGDPCQACSLRVCRECRVAGPNGSWKCTVCDKIAQLRIITGEWFFEEKAKRFKQVNVLGTDVVRQSILRRSPGAEEVQSQEQTRQDAEKSDTSPVAGKKASHDGPKRKGFLLSKFRSATRGEIITPKTDTGRSYSLDLDGQHFRSLKSPPGSDRGSTGSSDLNDQEPGPRTPKSSRSNGVTPGTQSSPAPSTRTVTSVISREYGFENSMDLAAIEGTSQELTKSHRRNTSGTPSIAVSGTSLSSDQSRSELDLSESFTEDSEDTVSIRSKSVPGALDKDSLEETEESIDALVSSQLSTNTHRLASGLSTTSLNSMMSVYSETGDYGNVKVSGEILLHISYCYKTGGLYIFVKNCRNLAIGDEKKQRTDAYVKSYLLPDKSRNNKRKTKIRTGTNPEFNETLKYTISHTQLETRTLQLSVWHYDRFGRNSFLGEVEIPFDSWNFENPTDEWFVLQPKVEFAPDIGLQYKGELTVVLRYIPPEENLMLPPEQLQGNKTFKKGKKKESPVISGGILEVFIKEAKNLTAVKSGGTSDSFVKGYLLPDDSKATKHKTLVIKKSVNPQWNHTFMFSGIHPQDIKNVCLELTIWDKEAFSSNIFLGGVRLNSGSGVSHGKNVDWMDSQGEEQRLWQKMANNPGTPFEGVLMLRSSMGKCRL", "length": 730 }, "evidence": [ { "id": "F1NUG3", "url": "https://omabrowser.org/oma/group/F1NUG3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "phospholipid binding", "id": "GO:0005543", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005543", "evidence": [ { "database": "UniProtKB", "id": "F1NUG3", "url": "https://www.uniprot.org/uniprotkb/F1NUG3" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "F1NUG3", "url": "https://www.uniprot.org/uniprotkb/F1NUG3" } ], "pmid": "" }, { "name": "small GTPase binding", "id": "GO:0031267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031267", "evidence": [ { "database": "UniProtKB", "id": "F1NUG3", "url": "https://www.uniprot.org/uniprotkb/F1NUG3" } ], "pmid": "" }, { "name": "neurexin family protein binding", "id": "GO:0042043", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042043", "evidence": [ { "database": "UniProtKB", "id": "F1NUG3", "url": "https://www.uniprot.org/uniprotkb/F1NUG3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F1NUG3", "url": "https://www.uniprot.org/uniprotkb/F1NUG3" } ], "pmid": "" }, { "name": "exocytic vesicle", "id": "GO:0070382", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070382", "evidence": [ { "database": "UniProtKB", "id": "F1NUG3", "url": "https://www.uniprot.org/uniprotkb/F1NUG3" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "F1NUG3", "url": "https://www.uniprot.org/uniprotkb/F1NUG3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "intracellular protein transport", "id": "GO:0006886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006886", "evidence": [ { "database": "UniProtKB", "id": "F1NUG3", "url": "https://www.uniprot.org/uniprotkb/F1NUG3" } ], "pmid": "" }, { "name": "exocytosis", "id": "GO:0006887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006887", "evidence": [ { "database": "UniProtKB", "id": "F1NUG3", "url": "https://www.uniprot.org/uniprotkb/F1NUG3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 241, "end_pos": 243, "annotation": "n_glycosylation_sequon" }, { "start_pos": 260, "end_pos": 262, "annotation": "n_glycosylation_sequon" }, { "start_pos": 448, "end_pos": 450, "annotation": "n_glycosylation_sequon" }, { "start_pos": 501, "end_pos": 503, "annotation": "n_glycosylation_sequon" }, { "start_pos": 508, "end_pos": 510, "annotation": "n_glycosylation_sequon" }, { "start_pos": 632, "end_pos": 634, "annotation": "n_glycosylation_sequon" }, { "start_pos": 674, "end_pos": 676, "annotation": "n_glycosylation_sequon" }, { "start_pos": 9, "end_pos": 11, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1NUG3-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 764, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1NUG3-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1NUG3" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 317 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 241, "end_pos": 243 }, { "start_pos": 260, "end_pos": 262 }, { "start_pos": 448, "end_pos": 450 }, { "start_pos": 501, "end_pos": 503 }, { "start_pos": 508, "end_pos": 510 }, { "start_pos": 632, "end_pos": 634 }, { "start_pos": 674, "end_pos": 676 }, { "start_pos": 9, "end_pos": 11 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", 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The reference sequence was derived from JAENSK010000012.1. 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"database": "UniProtKB", "id": "F1NV74", "url": "https://www.uniprot.org/uniprotkb/F1NV74" } ], "pmid": "" }, { "name": "cellular response to hormone stimulus", "id": "GO:0032870", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032870", "evidence": [ { "database": "UniProtKB", "id": "F1NV74", "url": "https://www.uniprot.org/uniprotkb/F1NV74" } ], "pmid": "" }, { "name": "positive regulation of vasoconstriction", "id": "GO:0045907", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045907", "evidence": [ { "database": "UniProtKB", "id": "F1NV74", "url": "https://www.uniprot.org/uniprotkb/F1NV74" } ], "pmid": "" }, { "name": "regulation of systemic arterial blood pressure by vasopressin", "id": "GO:0001992", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001992", "evidence": [ { "database": "UniProtKB", "id": "F1NV74", "url": "https://www.uniprot.org/uniprotkb/F1NV74" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 27, "end_pos": 29, "annotation": 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[ { "name": "UNC45B", "type": "recommended", "evidence": [ { "id": "F1NVB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NVB3" } ] }, { "name": "UNC45B", "type": "synonym", "evidence": [ { "id": "XP_046758531", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046758531" } ] } ], "protein_names": [ { "name": "Protein unc-45 homolog B", "type": "recommended", "evidence": [ { "id": "F1NVB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NVB3/entry#names_and_taxonomy" } ] }, { "name": "protein unc-45 homolog B", "type": "synonym", "evidence": [ { "id": "XP_046758531", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046758531" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052550.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_046758531", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046758531" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NVB3", "url": "https://www.uniprot.org/uniprotkb/F1NVB3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "UNC45B", "url": "https://www.uniprot.org/uniprotkb/F1NVB3", "locus": { "chromosome": "19", "start_pos": 4949770, "end_pos": 4958473, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029628", "url": "https://www.ensembl.org/id/ENSGALG00010029628" } ] } } ], "crossref": [ { "id": "F1NVB3", "url": "https://alphafold.ebi.ac.uk/entry/F1NVB3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000002186", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000002186", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "417527", "url": "https://www.ncbi.nlm.nih.gov/gene/417527", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000225", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000225", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011990", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011990", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019734", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019734", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024660", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024660", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:417527", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417527", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DTQTRRW", "url": "https://omabrowser.org/oma/group/DTQTRRW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1NVB3", "url": "https://www.orthodb.org/?gene=F1NVB3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45994", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45994", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45994:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45994:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF11701", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11701", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_046758531", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046758531", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1NVB3", "url": "https://www.uniprot.org/uniprotkb/F1NVB3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NVB3-1", "url": "https://www.uniprot.org/uniprotkb/F1NVB3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEDPIQLKEEGNKYFQASDYERAAQSYTQAMKLNKDRALQAVLYRNRAACFLKREEYAKAASDASRAIDINSSDIKALYRRSQALEKLGKLDQAFKDAQKCATMEPHNKNFQETLRRLGADIQEKLRIQFSTDMRVQKMFEILLDENSEKEKREKAANNLIVLGREEAGAERIFQNNGVSLLLQLIETKNAELVLAAVRTLSGMCTGHKARATAILHYLGIDNICMWMSVDNEEISLAVCNLLQTITDCLLGQGKEEHHGKEEAVVLDTKKDLKMITMRLLDMLVSKNVSGQGRDRALNLLNKNIPRKDLKDQDNSRTTFVIDNGLKKILKVVGQIPEMPGCLPLTENTQLTASILLNKLYDDLRCDPERDNYRVICEEYIKSKIDPQNMDKTLHAIQIVSGVLQGPFDLGNKLLGMKGVMEMMVALCGSEREIDQLVAVEALIHASTKLSRATFIISNGITLLKEIYKKTKNEKIKIRALVGLCKLGSAGGTDYGLRQFAEGSTEKLARQCRKWLCNTSIDARTRKWAVEGLAYLTLDADVKDDFVEDEQALQAMFELAKTSDKTILYSVASALVNCTNSYDTKELVPELVQLAKFSKQHVPEEHPKDKKDFVVKRVKRLLKAGVVSALACMVKADSAILTDQSKELIARVFLALCDDPKDRGTIVAQGGGKALIPLAVEGTDVGKIKASHALAKIAAISNPDIAFPGERVYEVVRPLVSLLNTERDGLQNYEALLGLTNFSGRSDKLRMKIVKEGALPDIENYMFENHDQLRQAATECMCNLVVSKEVQERFVADGNDRLKLVVLLCGEDDEKVQKAAAGALAMLTAAQKKLCSKMTEVTTQWLEILQRLCLHDNMEVQHRGLVIAFNLISASKELAKKLVESELLEILTYVGKQEDDPKKQHIINAARDCLTKCMDYGLIKPLSRA", "length": 929, "header": "tr|F1NVB3-1|F1NVB3_CHICK Isoform 1 of Protein unc-45 homolog B OS=Gallus gallus OX=9031 GN=UNC45B PE=4 SV=4 CANONICAL=F1NVB3-1" }, "isoforms": [ { "isoform_ac": "F1NVB3-1", "url": "https://www.uniprot.org/uniprotkb/F1NVB3/entry#F1NVB3-1", "sequence": { "sequence": "MEDPIQLKEEGNKYFQASDYERAAQSYTQAMKLNKDRALQAVLYRNRAACFLKREEYAKAASDASRAIDINSSDIKALYRRSQALEKLGKLDQAFKDAQKCATMEPHNKNFQETLRRLGADIQEKLRIQFSTDMRVQKMFEILLDENSEKEKREKAANNLIVLGREEAGAERIFQNNGVSLLLQLIETKNAELVLAAVRTLSGMCTGHKARATAILHYLGIDNICMWMSVDNEEISLAVCNLLQTITDCLLGQGKEEHHGKEEAVVLDTKKDLKMITMRLLDMLVSKNVSGQGRDRALNLLNKNIPRKDLKDQDNSRTTFVIDNGLKKILKVVGQIPEMPGCLPLTENTQLTASILLNKLYDDLRCDPERDNYRVICEEYIKSKIDPQNMDKTLHAIQIVSGVLQGPFDLGNKLLGMKGVMEMMVALCGSEREIDQLVAVEALIHASTKLSRATFIISNGITLLKEIYKKTKNEKIKIRALVGLCKLGSAGGTDYGLRQFAEGSTEKLARQCRKWLCNTSIDARTRKWAVEGLAYLTLDADVKDDFVEDEQALQAMFELAKTSDKTILYSVASALVNCTNSYDTKELVPELVQLAKFSKQHVPEEHPKDKKDFVVKRVKRLLKAGVVSALACMVKADSAILTDQSKELIARVFLALCDDPKDRGTIVAQGGGKALIPLAVEGTDVGKIKASHALAKIAAISNPDIAFPGERVYEVVRPLVSLLNTERDGLQNYEALLGLTNFSGRSDKLRMKIVKEGALPDIENYMFENHDQLRQAATECMCNLVVSKEVQERFVADGNDRLKLVVLLCGEDDEKVQKAAAGALAMLTAAQKKLCSKMTEVTTQWLEILQRLCLHDNMEVQHRGLVIAFNLISASKELAKKLVESELLEILTYVGKQEDDPKKQHIINAARDCLTKCMDYGLIKPLSRA", "length": 929, "header": "tr|F1NVB3-1|F1NVB3_CHICK Isoform 1 of Protein unc-45 homolog B OS=Gallus gallus OX=9031 GN=UNC45B PE=4 SV=4 CANONICAL=F1NVB3-1" }, "locus": { "chromosome": "19", "start_pos": 4958473, "end_pos": 4950271, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071640.1", "url": "https://www.ensembl.org/id/ENSGALT00010071640.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044330.1", "url": "https://www.ensembl.org/id/ENSGALP00010044330.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:417527", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417527", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D4A8U9-1", "protein_name": "Protein unc-45 homolog B", "gene_name": "Unc45b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAEAEATQLKEEGNQHFQRQDYKAATKSYSQALKLTKDKALLATLYRNRAACGLKMESYAQAASDASRAIDINSADIKALYRRCQALEHLGKLDQAFKDVQRCATLEPRNQNFQETLRRLNTSIQEQLRVQFSTDSRVQTMFEILLNENSEADKREKAANNLIVLGREEAGAERIFQSNGVALLLQLMDAKRPELVLAAVRTLSGMCSGHRARATAILHAVRIDRICSLMALENEEMSLAVCSLLQAIIDSLSGEDKREHRGKEEALVLDTKKDLKQITSHLLDMLVSKKVSGQGRDQALNLLNKNVPRKDLSIHDNSRTIYVVDNGLRKVLKVVGQVPDLPSCLPLTDNTRMLASILINKLYEDLRCDPERDHFRKICEEYITSKFDPQDMDKNVNAIQTVSGILQGPFDLGNQLLGMKGVMEMMVALCGSEREADQLVAVEALIHASTKLSRATFIITNGVTLLKQIYKTTKNEKIKIRTLVGLCKLGSAGGSDYGLRQFAEGSTEKLAKQCRKWLCNTAIDTRTRRWAVEGLAYLTLDADVKDDFVQDIPALQAMFELAKTSDKTILYSVANTLVNCTNSYDVKEVVPELVQLAKFSKQHVPEEHPKDKKDFVDLRVKRLLKAGVISALACMVKADSAILTDQTKELLARVFLALCDNPKDRGTIVAQGGGKALIPLALEGTDVGKVKAAHGLAKIAAVSNPDIAFPGERVYEVVRPLVSLLDTQRDGLQNYEALLGLTNLSGRSDKLRQKIFKEKALPDIENYMFENHDQLRQAATECMCNMVLNKEVQERFLADGNDRLKLVVLLCGEDDHKLQNAAAGALAMLTAAHKKLCLKMTEVTTQWLEILQRLCLHDQLSVQHRGLVIAYNLLSADAELARKLVETELLEILTVVGKQEPDETRAAVVQTARECLIKCMDYGFIKPVS", "length": 929 }, "evidence": [ { "id": "F1NVB3", "url": "https://omabrowser.org/oma/group/F1NVB3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6DGE9-1", "protein_name": "Protein unc-45 homolog B", "gene_name": "unc45b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTMGEIGDSVQLKEEGNKHFQAGEIDQAIDCYTKAIKTCKKEDKKALAVIYRNRSACFLKKENYSNAASDATKAIDVDAADIKALYRRCQAFEKLGKLDMAFKDVQRCATIEPKNKTFLETLRRLGAEIQQKLKTTFSTDSRVQNMFDILFSDEPDKEKREKAANNLIVLAREDAGAERIFQNNGVPLLMQLIDTGKPEMILAAIRTLSGMCTGHRARATAIIHSVGISKLCSIMAVDNEEIALATANLFQCVNDSLSGGDKRNYGKEEALVLDSSKDLKDILLALLEMIASKNVSGHGRDQALNLLTKNVPRQNKKSTDNSKCLFTIDHGLKKILKVCGQVPDLPDQLPMTENTQLIASVLLSKLYDDLRCDPERDQFRDICDDYIKSKFDPNDMDKNIHAINTLSGILQGPFDLGNVLAGRQGVMEMMVALCGSEREVDQLVAVEALIHASTKTSKASFFISNGVSLLKEMYKKTKNEKIKIRALVGLCKLGSAGGDDYSMRQFAEGSTEKLAKQCRKWLCNPTLDVRTRKWAIEGLAYLTNDADVKDDFAEDEPAMRAMFELTKSNDKTILYAVACTLVNCTNSYDKKEIIPEMVQLAKFSKQHVPEQHPKDKKDFIVRRVKRLLKAGVTSALAVMVKADNSILTDQTKEMLARVFLALTEDVKDRGIIVAQGGGKALIPLALEGTDKGKIKASHALAKIAAVSNPEIAFPGERIYEVVRPLVSLLGTDRDGMENFEALRGLTNLAGLNDKLRVKILKEKALPEIENYMFEDHEQIRQAATECMCNLVCCKEVQDRYLEDGNDKLKLLVLLCGEDEEKLQRAAAGALAMLTAAQKKLAVKMTKVTEQWLEILQRLCIHDNPEIQHRGLVTVFNMLDADDQLAKKLVESDMLEILTYVAKLEDNPKKQNAIDAARACLSKAMDNGLIKPFSN", "length": 934 }, "evidence": [ { "id": "F1NVB3", "url": "https://omabrowser.org/oma/group/F1NVB3/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q8CGY6-1", "protein_name": "Protein unc-45 homolog B", "gene_name": "Unc45b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAEAEAAQLKEEGNRHFQLQDYKAATKSYSQALKLTKDKALLATLYRNRAACGLKMESYAQAASDASRAIDINSADIKALYRRCQALEHLGKLDQAFKDVQRCATLEPRNQNFQETLRRLNTSIQEQLRVQFSTDSRVQTMFEILLNENSEADKREKAANNLIVLGREEAGAERIFQSNGVALLLQLMNTQRPELLLAAVRTLSGMCSGHRARATAILHAVRIDRICSLMALENEEMSLAVCNLLQAIIDSLSGEDKREHRGKEEALVLDTKKDLKQITSHLLDMLVSKKVSGQGRDQALNLLNKNVPRKDLSIHDNSRTIYVVDNGLRKILKVVGQVPDLPSCLPLTDNTRMLASILINKLYDDLRCDPERDHFRKICEEYITSKFDPQDMDKNVNAIQTVSGILQGPFDLGNQLLGMKGVMEMMVALCGSEREADQLVAVEALIHASTKLSRATFIITNGVTLLKQIYKTTKNEKIKIRTLVGLCKLGSAGGSDYGLRQFAEGSTEKLAKQCRKWLCNTAIDTRTRRWAVEGLAYLTLDADVKDDFVQDIPALQAMFELAKARTSDKTILYSVANTLVNCTNSYDVKEVVPELVQLAKFSKQHVPEEHPKDKKDFVDLRVKRLLKAGVISALACMVKADSAILTDQTKELLARVFLALCDNPKDRGTIVAQGGGKALIPLALEGTDVGKVKAAHGLAKIAAVSNPDIAFPGERVYEVVRPLVSLLDTQRDGLQNYEALLGLTNLSGRSDKLRQKIFKEKALPDIENYMFENHDQLRQAATECMCNMVLNKEVQERFLADGNDRLKLVVLLCGEDDHKLQNAAAGALAMLTAAHKKLCLKMTEVTTQWLEILQRLCLHDQLSVQHRGLVIAHNLLSADAELARKLVESELLEILTVVGKQEPDEKRAAVVQTARECLIKCMDYGFIKPVS", "length": 931 }, "evidence": [ { "id": "F1NVB3", "url": "https://omabrowser.org/oma/group/F1NVB3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8IWX7-1", "protein_name": "Protein unc-45 homolog B", "gene_name": "UNC45B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAEVEAVQLKEEGNRHFQLQDYKAATNSYSQALKLTKDKALLATLYRNRAACGLKTESYVQAASDASRAIDINSSDIKALYRRCQALEHLGKLDQAFKDVQRCATLEPRNQNFQEMLRRLNTSIQEKLRVQFSTDSRVQKMFEILLDENSEADKREKAANNLIVLGREEAGAEKIFQNNGVALLLQLLDTKKPELVLAAVRTLSGMCSGHQARATVILHAVRIDRICSLMAVENEEMSLAVCNLLQAIIDSLSGEDKREHRGKEEALVLDTKKDLKQITSHLLDMLVSKKVSGQGRDQALNLLNKNVPRKDLAIHDNSRTIYVVDNGLRKILKVVGQVPDLPSCLPLTDNTRMLASILINKLYDDLRCDPERDHFRKICEEYITGKFDPQDMDKNLNAIQTVSGILQGPFDLGNQLLGLKGVMEMMVALCGSERETDQLVAVEALIHASTKLSRATFIITNGVSLLKQIYKTTKNEKIKIRTLVGLCKLGSAGGTDYGLRQFAEGSTEKLAKQCRKWLCNMSIDTRTRRWAVEGLAYLTLDADVKDDFVQDVPALQAMFELAKAGTSDKTILYSVATTLVNCTNSYDVKEVIPELVQLAKFSKQHVPEEHPKDKKDFIDMRVKRLLKAGVISALACMVKADSAILTDQTKELLARVFLALCDNPKDRGTIVAQGGGKALIPLALEGTDVGKVKAAHALAKIAAVSNPDIAFPGERVYEVVRPLVRLLDTQRDGLQNYEALLGLTNLSGRSDKLRQKIFKERALPDIENYMFENHDQLRQAATECMCNMVLHKEVQERFLADGNDRLKLVVLLCGEDDDKVQNAAAGALAMLTAAHKKLCLKMTQVTTQWLEILQRLCLHDQLSVQHRGLVIAYNLLAADAELAKKLVESELLEILTVVGKQEPDEKKAEVVQTARECLIKCMDYGFIKPVS", "length": 931 }, "evidence": [ { "id": "F1NVB3", "url": "https://omabrowser.org/oma/group/F1NVB3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1NVB3", "url": "https://www.uniprot.org/uniprotkb/F1NVB3" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F1NVB3", "url": "https://www.uniprot.org/uniprotkb/F1NVB3" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "F1NVB3", "url": "https://www.uniprot.org/uniprotkb/F1NVB3" } ], "pmid": "" }, { "name": "Z disc", "id": "GO:0030018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030018", "evidence": [ { "database": "UniProtKB", "id": "F1NVB3", "url": "https://www.uniprot.org/uniprotkb/F1NVB3" } ], "pmid": "" }, { "name": "A band", "id": "GO:0031672", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031672", "evidence": [ { "database": "UniProtKB", "id": "F1NVB3", "url": "https://www.uniprot.org/uniprotkb/F1NVB3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "F1NVB3", "url": "https://www.uniprot.org/uniprotkb/F1NVB3" } ], "pmid": "" }, { "name": "muscle organ development", "id": "GO:0007517", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007517", "evidence": [ { "database": "UniProtKB", "id": "F1NVB3", "url": "https://www.uniprot.org/uniprotkb/F1NVB3" } ], "pmid": "" }, { "name": "protein folding", "id": "GO:0006457", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006457", "evidence": [ { "database": "UniProtKB", "id": "F1NVB3", "url": "https://www.uniprot.org/uniprotkb/F1NVB3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "Hsp90 protein binding", "id": "GO:0051879", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051879", "evidence": [ { "database": "UniProtKB", "id": "F1NVB3", "url": "https://www.uniprot.org/uniprotkb/F1NVB3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 288, "end_pos": 290, "annotation": "n_glycosylation_sequon" }, { "start_pos": 518, "end_pos": 520, "annotation": "n_glycosylation_sequon" }, { "start_pos": 577, "end_pos": 579, "annotation": "n_glycosylation_sequon" }, { "start_pos": 71, "end_pos": 73, "annotation": "n_glycosylation_sequon" }, { "start_pos": 741, "end_pos": 743, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1NVB3-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 929, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1NVB3-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1NVB3" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1NVB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NVB3" }, { "id": "PF11701", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11701" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "UNC-45/Cro1/She4 central", "eco_id": "ECO_0000259", "start_pos": 295, "end_pos": 512, "start_aa": "Asp", "end_aa": "Cys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 288, "end_pos": 290 }, { "start_pos": 518, "end_pos": 520 }, { "start_pos": 577, "end_pos": 579 }, { "start_pos": 71, "end_pos": 73 }, { "start_pos": 741, "end_pos": 743 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1NVK6-1", "uniprot_ac": "F1NVK6", "uniprot_id": "TM237_CHICK", "mass": { "chemical_mass": 44406.0, "monoisotopic_mass": 44406.0 }, "refseq": {}, "gene_names": [ { "name": "TMEM237", "type": "recommended", "evidence": [ { "id": "F1NVK6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NVK6" } ] } ], "protein_names": [ { "name": "Transmembrane protein 237", "type": "recommended", "evidence": [ { "id": "F1NVK6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NVK6/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Component of the transition zone in primary cilia. Required for ciliogenesis (By similarity).", "evidence": [ { "database": "UniProtKB", "id": "F1NVK6", "url": "https://www.uniprot.org/uniprotkb/F1NVK6#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NVK6", "url": "https://www.uniprot.org/uniprotkb/F1NVK6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TMEM237", "url": "https://www.uniprot.org/uniprotkb/F1NVK6", "locus": { "chromosome": "7", "start_pos": 11121351, "end_pos": 11134972, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010024930", "url": "https://www.ensembl.org/id/ENSGALG00010024930" } ] } } ], "crossref": [ { "id": "F1NVK6", "url": "https://alphafold.ebi.ac.uk/entry/F1NVK6", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR029409", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029409", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "F1NVK6", "url": "https://www.orthodb.org/?gene=F1NVK6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR28388", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28388", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR28388:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28388:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15383", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15383", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "F1NVK6", "url": "https://www.uniprot.org/uniprotkb/F1NVK6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NVK6-1", "url": "https://www.uniprot.org/uniprotkb/F1NVK6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGKKQVCPPRALPPVPSFCSADDIPLSRPKKRKPKGKTPLDDIVQATVRRQSESSEPLTPEPQDVPPQRKRKKKKVPPDSETSFTQQNTASLFQNGNGVDVPEAEETVVRKQRKRTKKARPAETHSSNELEVEEDDIIEDEHRRSPDQQPVFAAPTGISQPVSKVFVEKNRRFQAADRAELIKTTENINVLLDVKSSWTTRDVALSVHRSFRVIGLFTHGFLAGYAVWNIVVIYILAGNQLTTVSNLLQQYKMLAYPAQSLFYLLLSISTVSAFDRIDLAKASVALRGFLTLDPAALASFLYFTALILSLSQQMTCDRINLYTPPSENGSIWTAGMEEEILQPWIVVNLVVSILVGASWIFLSYRPELDHSEELMFHTEIEEFPQDEREMLKSQ", "length": 394, "header": "sp|F1NVK6-1|TM237_CHICK Isoform 1 of Transmembrane protein 237 OS=Gallus gallus OX=9031 GN=TMEM237 PE=3 SV=2 CANONICAL=F1NVK6-1" }, "isoforms": [ { "isoform_ac": "F1NVK6-1", "url": "https://www.uniprot.org/uniprotkb/F1NVK6/entry#F1NVK6-1", "sequence": { "sequence": "MGKKQVCPPRALPPVPSFCSADDIPLSRPKKRKPKGKTPLDDIVQATVRRQSESSEPLTPEPQDVPPQRKRKKKKVPPDSETSFTQQNTASLFQNGNGVDVPEAEETVVRKQRKRTKKARPAETHSSNELEVEEDDIIEDEHRRSPDQQPVFAAPTGISQPVSKVFVEKNRRFQAADRAELIKTTENINVLLDVKSSWTTRDVALSVHRSFRVIGLFTHGFLAGYAVWNIVVIYILAGNQLTTVSNLLQQYKMLAYPAQSLFYLLLSISTVSAFDRIDLAKASVALRGFLTLDPAALASFLYFTALILSLSQQMTCDRINLYTPPSENGSIWTAGMEEEILQPWIVVNLVVSILVGASWIFLSYRPELDHSEELMFHTEIEEFPQDEREMLKSQ", "length": 394, "header": "sp|F1NVK6-1|TM237_CHICK Isoform 1 of Transmembrane protein 237 OS=Gallus gallus OX=9031 GN=TMEM237 PE=3 SV=2 CANONICAL=F1NVK6-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Sequence and comparative analysis of the chicken genome provide unique perspectives on vertebrate evolution.", "journal": "Nature", "date": "2004", "authors": "", "evidence": [ { "database": "UniProtKB", "id": "F1NVK6", "url": "https://www.uniprot.org/uniprotkb/F1NVK6" } ], "reference": [ { "type": "PubMed", "id": "15592404", "url": "https://glygen.org/publication/PubMed/15592404" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "F1NVK6", "url": "https://www.uniprot.org/uniprotkb/F1NVK6" } ], "pmid": "" }, { "name": "ciliary transition zone", "id": "GO:0035869", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035869", "evidence": [ { "database": "UniProtKB", "id": "F1NVK6", "url": "https://www.uniprot.org/uniprotkb/F1NVK6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "cilium assembly", "id": "GO:0060271", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060271", "evidence": [ { "database": "UniProtKB", "id": "F1NVK6", "url": "https://www.uniprot.org/uniprotkb/F1NVK6" } ], "pmid": "" }, { "name": "regulation of Wnt signaling pathway", "id": "GO:0030111", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030111", "evidence": [ { "database": "UniProtKB", "id": "F1NVK6", "url": "https://www.uniprot.org/uniprotkb/F1NVK6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 328, "end_pos": 330, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1NVK6-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 394, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1NVK6-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1NVK6" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 328, "end_pos": 330 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "F1NVP6-1", "uniprot_ac": "F1NVP6", "uniprot_id": "F1NVP6_CHICK", "mass": { "chemical_mass": 24455.0, "monoisotopic_mass": 24455.0 }, "refseq": { "ac": "NP_001264773", "name": "protein N-lysine methyltransferase METTL21A isoform a", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264773" }, "gene_names": [ { "name": "METTL21A", "type": "recommended", "evidence": [ { "id": "F1NVP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NVP6" } ] }, { "name": "FAM119A", "type": "synonym", "evidence": [ { "id": "NP_001264773", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264773" } ] }, { "name": "METTL21A", "type": "synonym", "evidence": [ { "id": "NP_001264773", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264773" } ] } ], "protein_names": [ { "name": "Protein N-lysine methyltransferase METTL21A", "type": "recommended", "evidence": [ { "id": "F1NVP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NVP6/entry#names_and_taxonomy" } ] }, { "name": "Methyltransferase-like protein 21A", "type": "synonym", "evidence": [ { "id": "F1NVP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NVP6/entry#names_and_taxonomy" } ] }, { "name": "family with sequence similarity 119, member A", "type": "synonym", "evidence": [ { "id": "NP_001264773", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264773" } ] }, { "name": "protein N-lysine methyltransferase METTL21A isoform a", "type": "synonym", "evidence": [ { "id": "NP_001264773", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264773" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: SRR13267652.264.1, BX931194.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000236.1. On Apr 24, 2013 this sequence version replaced XP_421949.1. Transcript Variant: This variant (1) encodes the longest isoform (a).", "evidence": [ { "database": "RefSeq", "id": "NP_001264773", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264773" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NVP6", "url": "https://www.uniprot.org/uniprotkb/F1NVP6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "METTL21A", "url": "https://www.uniprot.org/uniprotkb/F1NVP6", "locus": { "chromosome": "7", "start_pos": 11802396, "end_pos": 11796638, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010025340", "url": "https://www.ensembl.org/id/ENSGALG00010025340" } ] } } ], "crossref": [ { "id": "F1NVP6", "url": "https://alphafold.ebi.ac.uk/entry/F1NVP6", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000008493", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000008493", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd02440", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02440", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "424094", "url": "https://www.ncbi.nlm.nih.gov/gene/424094", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR019410", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019410", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029063", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029063", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:424094", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424094", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "LFWELCD", "url": "https://omabrowser.org/oma/group/LFWELCD/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1NVP6", "url": "https://www.orthodb.org/?gene=F1NVP6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14614", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14614", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14614:SF14", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14614:SF14", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10294", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10294", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-8876725", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8876725", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001264773", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264773", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "54192", "url": "https://www.rhea-db.org/rhea/54192", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "F1NVP6", "url": "https://www.uniprot.org/uniprotkb/F1NVP6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NVP6-1", "url": "https://www.uniprot.org/uniprotkb/F1NVP6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MALVPYEEGRALQGLRRPTATYRFAGRTVRIRQDWERRGVAAVVWDAAVVLSAYLEMGGIDLRDRSVIELGAGTGLLGIVATLLGARVTITDREPALEFLESNVWANLPSELHARAVVKELTWGKDLGSFPPGAFDFILGADIIYLEETFAELLRTLEHLCSEQTVILLSCRIRYERDNNFLKMLKGRFSVSEVHYDYSKDVHIYKAQRHSHNDDF", "length": 216, "header": "tr|F1NVP6-1|F1NVP6_CHICK Isoform 1 of Protein N-lysine methyltransferase METTL21A OS=Gallus gallus OX=9031 GN=METTL21A PE=3 SV=2 CANONICAL=F1NVP6-1" }, "isoforms": [ { "isoform_ac": "F1NVP6-1", "url": "https://www.uniprot.org/uniprotkb/F1NVP6/entry#F1NVP6-1", "sequence": { "sequence": "MALVPYEEGRALQGLRRPTATYRFAGRTVRIRQDWERRGVAAVVWDAAVVLSAYLEMGGIDLRDRSVIELGAGTGLLGIVATLLGARVTITDREPALEFLESNVWANLPSELHARAVVKELTWGKDLGSFPPGAFDFILGADIIYLEETFAELLRTLEHLCSEQTVILLSCRIRYERDNNFLKMLKGRFSVSEVHYDYSKDVHIYKAQRHSHNDDF", "length": 216, "header": "tr|F1NVP6-1|F1NVP6_CHICK Isoform 1 of Protein N-lysine methyltransferase METTL21A OS=Gallus gallus OX=9031 GN=METTL21A PE=3 SV=2 CANONICAL=F1NVP6-1" }, "locus": { "chromosome": "7", "start_pos": 11799229, "end_pos": 11797031, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010061875.1", "url": "https://www.ensembl.org/id/ENSGALT00010061875.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038199.1", "url": "https://www.ensembl.org/id/ENSGALP00010038199.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:424094", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424094", "resource": "KEGG Pathway" }, { "id": "R-GGA-8876725", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8876725", "resource": "Reactome", "description": "Protein methylation" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A4X1UXV9-1", "protein_name": "Protein N-lysine methyltransferase METTL21A", "gene_name": "METTL21A", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MALVPYEETAGMGLQRFHKPLATFSFANHRIQIQQDWKQLGVAAVVWDAAVVLSTYLEMGAVELRGCSAVELGAGTGLVGIVAALLGAHVTITDRKVALEFLKSNVQANLPPHIQPKAVVKELTWGQNLGSFSPGEFDLILGADIIYLEETFTDLLRTLEHLCSNHSVILLACRIRYERDHNFLAMLERQFTVSKVHYDPEKDVHIYKAQKRNLREDL", "length": 218 }, "evidence": [ { "id": "F1NVP6", "url": "https://omabrowser.org/oma/group/F1NVP6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A4FV42-1", "protein_name": "Protein N-lysine methyltransferase METTL21A", "gene_name": "METTL21A", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MALVPYTETAEMGLQRFHKPLATFSFANHTIQIRQDWKQLGVAAVVWDAAVVLATYLEMGTVELRGCSAVELGAGTGLVGIVAALLGAHVTITDRKVALEFLKSNVQANLPPHIQPKAVVKELTWGQNLGRFSPGEFDLILGADIIYLEETFTDLLQTLEHLCSNHSVVLLACRIRYERDYNFLAMLERQFTVSKVHYDSEKDVHIYKAQRRCLREDL", "length": 218 }, "evidence": [ { "id": "F1NVP6", "url": "https://omabrowser.org/oma/group/F1NVP6/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "D4A8Z5-1", "protein_name": "Protein N-lysine methyltransferase METTL21A", "gene_name": "Mettl21a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MALVPYEESMSIGLQKLHKPLATFSFANHTIQIRQDWGRLGVAAVVWDAAIVLSTYLEMGAVELRGCSAVELGAGTGLVGIVAALLGAHVTITDRKVALEFLKSNVEANLPPHIQPKVVVKELTWGQNLDSFSPGEFDLILGADIIYLEDTFTDLLQTLGHLCSNNSVILLACRIRYERDNNFLTMLERQFTVSKVHYDPEKDVHIYKAQKRKQREDL", "length": 218 }, "evidence": [ { "id": "F1NVP6", "url": "https://omabrowser.org/oma/group/F1NVP6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3HU65-1", "protein_name": "Protein N-lysine methyltransferase METTL21A", "gene_name": "Mettl21a", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MALVPYEESMEIGLQKFHKPLATFSFANHTIQIRQDWRQLGVAAVVWDAAIVLSTYLEMGAVELRGCSVVELGAGTGLVGIVAALLGAHVTITDRQVALEFLKSNVEANLPPHIQPKVVVKELTWGQNLESFSPGEFDLILGADVIYLEDTFTDLLQTLGHLCSSRSVILLACRIRYERDNNFLMMLERQFTVNKVHYDPEKDVHIYKAQKTDQREDL", "length": 218 }, "evidence": [ { "id": "F1NVP6", "url": "https://omabrowser.org/oma/group/F1NVP6/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q5BLD8-1", "protein_name": "Protein N-lysine methyltransferase METTL21A", "gene_name": "mettl21a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MALVPYDENVLPALSKLHQSSAEFTLANHRIRLSQDWKRLGVAAVVWDAAVVLCMFLEMGKVDLKGKRVIELGAGTGLVGIVAALLGANVTITDREPALEFLTANVHENIPQGRQKAVQVSELTWGENLDLYPQGGYDLILGADIVYLEETFPALLQTLEHLSSGDTVVLLSCRIRYERDERFLTELRQRFSVQEVHYDSQRDIHVYRAVKNKSNTEL", "length": 218 }, "evidence": [ { "id": "F1NVP6", "url": "https://omabrowser.org/oma/group/F1NVP6/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q8WXB1-1", "protein_name": "Protein N-lysine methyltransferase METTL21A", "gene_name": "METTL21A", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MALVPYEETTEFGLQKFHKPLATFSFANHTIQIRQDWRHLGVAAVVWDAAIVLSTYLEMGAVELRGRSAVELGAGTGLVGIVAALLGAHVTITDRKVALEFLKSNVQANLPPHIQTKTVVKELTWGQNLGSFSPGEFDLILGADIIYLEETFTDLLQTLEHLCSNHSVILLACRIRYERDNNFLAMLERQFTVRKVHYDPEKDVHIYEAQKRNQKEDL", "length": 218 }, "evidence": [ { "id": "F1NVP6", "url": "https://omabrowser.org/oma/group/F1NVP6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9CQL0-1", "protein_name": "Protein N-lysine methyltransferase METTL21A", "gene_name": "Mettl21A", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALVPYEESAAIGLQKFHKPLATFSFANHTIQIRQDWRQLGVAAVVWDAAVVLSMYLEMGAVELRGCSAVELGAGTGLVGIVAALLGAQVTITDRKVALEFLKSNVEANLPPHIQPKAVVKELTWGQNLESFSPGEFDLILGADVIYLEDTFTDLLQTLGHLCSNNSVILLACRIRYERDSNFLTMLERQFTVSKVHYDPEKDVHIYKAQKRNQREDL", "length": 218 }, "evidence": [ { "id": "F1NVP6", "url": "https://omabrowser.org/oma/group/F1NVP6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9FFH2-1", "protein_name": "S-adenosyl-L-methionine-dependent methyltransferases superfamily protein", "gene_name": "MLN1.9", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MKFTDSPVIDLTVNGTKLSIQQDNGSMHVGTSVWPCSLILSKFAERWSTLDSSSSTTSPNPYAELFDFRRRRGIELGTGCGVAGMAFYLLGLTEIVLTDIAPVMPALKHNLKRNKTALGKSLKTSIVYWNNRDQISALKPPFDLVIAADVVYIEESVGQLVTAMELLVADDGAVLLGYQIRSPEADKLFWELCDIVFKIEKVPHEHLHSDYAYEETDVYIFRKKVKKNEAESVS", "length": 234 }, "evidence": [ { "id": "F1NVP6", "url": "https://omabrowser.org/oma/group/F1NVP6/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F1NVP6", "url": "https://www.uniprot.org/uniprotkb/F1NVP6" } ], "pmid": "" }, { "name": "protein-containing complex", "id": "GO:0032991", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032991", "evidence": [ { "database": "UniProtKB", "id": "F1NVP6", "url": "https://www.uniprot.org/uniprotkb/F1NVP6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "ATPase binding", "id": "GO:0051117", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051117", "evidence": [ { "database": "UniProtKB", "id": "F1NVP6", "url": "https://www.uniprot.org/uniprotkb/F1NVP6" } ], "pmid": "" }, { "name": "Hsp70 protein binding", "id": "GO:0030544", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030544", "evidence": [ { "database": "UniProtKB", "id": "F1NVP6", "url": "https://www.uniprot.org/uniprotkb/F1NVP6" } ], "pmid": "" }, { "name": "protein-lysine N-methyltransferase activity", "id": "GO:0016279", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016279", "evidence": [ { "database": "UniProtKB", "id": "F1NVP6", "url": "https://www.uniprot.org/uniprotkb/F1NVP6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "methylation", "id": "GO:0032259", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032259", "evidence": [ { "database": "UniProtKB", "id": "F1NVP6", "url": "https://www.uniprot.org/uniprotkb/F1NVP6" } ], "pmid": "" }, { "name": "negative regulation of protein folding", "id": "GO:1903333", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903333", "evidence": [ { "database": "UniProtKB", "id": "F1NVP6", "url": "https://www.uniprot.org/uniprotkb/F1NVP6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "54192", "name": "", "equation": "L-lysyl-[protein] + 3 S-adenosyl-L-methionine = N(6),N(6),N(6)-trimethyl-L-lysyl-[protein] + 3 S-adenosyl-L-homocysteine + 3 H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q5ZKT6-1", "Q5ZIZ2-1", "A0A8V0ZCE9-1", "A0A8V0X7P0-1" ], "evidence": [ { "id": "54192", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/54192" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A8V0X7P0", "gene_name": "METTL10", "activity": [ { "ec_number": "2.1.1.-", "activity": "", "evidence": [ { "id": "A0A8V0X7P0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X7P0" } ] } ] }, { "uniprot_ac": "A0A8V0ZCE9", "gene_name": "SMYD5", "activity": [ { "ec_number": "2.1.1.359", "activity": "L-lysyl(36)-[histone H3] + 3 S-adenosyl-L-methionine = N(6),N(6),N(6)-trimethyl-L-lysyl(36)-[histone H3] + 3 S-adenosyl-L-homocysteine + 3 H(+).", "evidence": [ { "id": "A0A8V0ZCE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCE9" } ] }, { "ec_number": "2.1.1.372", "activity": "L-lysyl(20)-[histone H4] + 3 S-adenosyl-L-methionine = N(6),N(6),N(6)-trimethyl-L-lysyl(20)-[histone H4] + 3 S-adenosyl-L-homocysteine + 3 H(+).", "evidence": [ { "id": "A0A8V0ZCE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCE9" } ] }, { "ec_number": "2.1.1.372", "activity": "", "evidence": [ { "id": "A0A8V0ZCE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCE9" } ] }, { "ec_number": "2.1.1.359", "activity": "", "evidence": [ { "id": "A0A8V0ZCE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCE9" } ] } ] }, { "uniprot_ac": "Q5ZIZ2", "gene_name": "SMYD5", "activity": [ { "ec_number": "2.1.1.359", "activity": "L-lysyl(36)-[histone H3] + 3 S-adenosyl-L-methionine = N(6),N(6),N(6)-trimethyl-L-lysyl(36)-[histone H3] + 3 S-adenosyl-L-homocysteine + 3 H(+).", "evidence": [ { "id": "Q5ZIZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZIZ2" } ] }, { "ec_number": "2.1.1.-", "activity": "", "evidence": [ { "id": "Q5ZIZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZIZ2" } ] }, { "ec_number": "2.1.1.372", "activity": "L-lysyl(20)-[histone H4] + 3 S-adenosyl-L-methionine = N(6),N(6),N(6)-trimethyl-L-lysyl(20)-[histone H4] + 3 S-adenosyl-L-homocysteine + 3 H(+).", "evidence": [ { "id": "Q5ZIZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZIZ2" } ] } ] }, { "uniprot_ac": "Q5ZKT6", "gene_name": "EEF1AKMT1", "activity": [ { "ec_number": "2.1.1.-", "activity": "", "evidence": [ { "id": "Q5ZKT6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKT6" } ] } ] } ], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1NVP6-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 216, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1NVP6-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1NVP6" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1NVP8-1", "uniprot_ac": "F1NVP8", "uniprot_id": "F1NVP8_CHICK", "mass": { "chemical_mass": 32869.0, "monoisotopic_mass": 32869.0 }, "refseq": { "ac": "NP_001382148", "name": "non-homologous end-joining factor 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001382148" }, "gene_names": [ { "name": "NHEJ1", "type": "recommended", "evidence": [ { "id": "F1NVP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NVP8" } ] }, { "name": "NHEJ1", "type": "synonym", "evidence": [ { "id": "NP_001382148", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001382148" } ] } ], "protein_names": [ { "name": "Non-homologous end-joining factor 1", "type": "recommended", "evidence": [ { "id": "F1NVP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NVP8/entry#names_and_taxonomy" } ] }, { "name": "non-homologous end-joining factor 1", "type": "synonym", "evidence": [ { "id": "NP_001382148", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001382148" } ] }, { "name": "nonhomologous end-joining factor 1", "type": "synonym", "evidence": [ { "id": "NP_001382148", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001382148" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: SRR13267654.94207.1, ERR2368565.365485.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000236.1. On or before Jun 14, 2021 this sequence version replaced XP_040559775.1, XP_040531572.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001382148", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001382148" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NVP8", "url": "https://www.uniprot.org/uniprotkb/F1NVP8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "NHEJ1", "url": "https://www.uniprot.org/uniprotkb/F1NVP8", "locus": { "chromosome": "7", "start_pos": 21921492, "end_pos": 21890108, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010022224", "url": "https://www.ensembl.org/id/ENSGALG00010022224" } ] } } ], "crossref": [ { "id": "F1NVP8", "url": "https://alphafold.ebi.ac.uk/entry/F1NVP8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000011335", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000011335", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd22285", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22285", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "424205", "url": "https://www.ncbi.nlm.nih.gov/gene/424205", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR015381", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015381", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038051", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038051", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052287", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052287", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR053829", "url": "https://www.ebi.ac.uk/interpro/entry/IPR053829", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "EFHCCPA", "url": "https://omabrowser.org/oma/group/EFHCCPA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1NVP8", "url": "https://www.orthodb.org/?gene=F1NVP8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR32235", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR32235", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR32235:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR32235:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF09302", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09302", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21928", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21928", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-5693571", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5693571", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001382148", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001382148", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1NVP8", "url": "https://www.uniprot.org/uniprotkb/F1NVP8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NVP8-1", "url": "https://www.uniprot.org/uniprotkb/F1NVP8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEHSEELESRLLTQPWASVCFDESTFIAKACFGDTGYMLLISDLSGVWYESADAEAVGQRSKELNKRLTAHVSSVLQRLHGLLSPALAGQPHAATSFSCQRPAGGLSLRVRSELSGLPFYWDFRCRPAPVATVCRHLVRPLVRMSLALQHQVQELTSLLLRKDAEIEDYRESGATLSRDRLRTEPFQEETFLQNIMAESLPQICSAEDGHAFTSALPQLYMAVTLQEAKQARKRHHPEDTEDLAPTAETSGHPDPAPQAPADETASLNEEATPTSSPVQKPRLPVAKAKPKKAKGLFS", "length": 298, "header": "tr|F1NVP8-1|F1NVP8_CHICK Isoform 1 of Non-homologous end-joining factor 1 OS=Gallus gallus OX=9031 GN=NHEJ1 PE=1 SV=4 CANONICAL=F1NVP8-1" }, "isoforms": [ { "isoform_ac": "F1NVP8-1", "url": "https://www.uniprot.org/uniprotkb/F1NVP8/entry#F1NVP8-1", "sequence": { "sequence": "MEHSEELESRLLTQPWASVCFDESTFIAKACFGDTGYMLLISDLSGVWYESADAEAVGQRSKELNKRLTAHVSSVLQRLHGLLSPALAGQPHAATSFSCQRPAGGLSLRVRSELSGLPFYWDFRCRPAPVATVCRHLVRPLVRMSLALQHQVQELTSLLLRKDAEIEDYRESGATLSRDRLRTEPFQEETFLQNIMAESLPQICSAEDGHAFTSALPQLYMAVTLQEAKQARKRHHPEDTEDLAPTAETSGHPDPAPQAPADETASLNEEATPTSSPVQKPRLPVAKAKPKKAKGLFS", "length": 298, "header": "tr|F1NVP8-1|F1NVP8_CHICK Isoform 1 of Non-homologous end-joining factor 1 OS=Gallus gallus OX=9031 GN=NHEJ1 PE=1 SV=4 CANONICAL=F1NVP8-1" }, "locus": { "chromosome": "7", "start_pos": 21921118, "end_pos": 21890458, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054075.1", "url": "https://www.ensembl.org/id/ENSGALT00010054075.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032606.1", "url": "https://www.ensembl.org/id/ENSGALP00010032606.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-5693571", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5693571", "resource": "Reactome", "description": "Nonhomologous End-Joining (NHEJ)" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "DNA ligase IV complex", "id": "GO:0032807", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032807", "evidence": [ { "database": "UniProtKB", "id": "F1NVP8", "url": "https://www.uniprot.org/uniprotkb/F1NVP8" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "F1NVP8", "url": "https://www.uniprot.org/uniprotkb/F1NVP8" } ], "pmid": "" }, { "name": "fibrillar center", "id": "GO:0001650", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001650", "evidence": [ { "database": "UniProtKB", "id": "F1NVP8", "url": "https://www.uniprot.org/uniprotkb/F1NVP8" } ], "pmid": "" }, { "name": "site of double-strand break", "id": "GO:0035861", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035861", "evidence": [ { "database": "UniProtKB", "id": "F1NVP8", "url": "https://www.uniprot.org/uniprotkb/F1NVP8" } ], "pmid": "" }, { "name": "DNA-dependent protein kinase-DNA ligase 4 complex", "id": "GO:0005958", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005958", "evidence": [ { "database": "UniProtKB", "id": "F1NVP8", "url": "https://www.uniprot.org/uniprotkb/F1NVP8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "telomere maintenance", "id": "GO:0000723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000723", "evidence": [ { "database": "UniProtKB", "id": "F1NVP8", "url": "https://www.uniprot.org/uniprotkb/F1NVP8" } ], "pmid": "" }, { "name": "double-strand break repair via nonhomologous end joining", "id": "GO:0006303", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006303", "evidence": [ { "database": "UniProtKB", "id": "F1NVP8", "url": "https://www.uniprot.org/uniprotkb/F1NVP8" } ], "pmid": "" }, { "name": "response to ionizing radiation", "id": "GO:0010212", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010212", "evidence": [ { "database": "UniProtKB", "id": "F1NVP8", "url": "https://www.uniprot.org/uniprotkb/F1NVP8" } ], "pmid": "" }, { "name": "B cell differentiation", "id": "GO:0030183", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030183", "evidence": [ { "database": "UniProtKB", "id": "F1NVP8", "url": "https://www.uniprot.org/uniprotkb/F1NVP8" } ], "pmid": "" }, { "name": "T cell differentiation", "id": "GO:0030217", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030217", "evidence": [ { "database": "UniProtKB", "id": "F1NVP8", "url": "https://www.uniprot.org/uniprotkb/F1NVP8" } ], "pmid": "" }, { "name": "immunoglobulin V(D)J recombination", "id": "GO:0033152", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033152", "evidence": [ { "database": "UniProtKB", "id": "F1NVP8", "url": "https://www.uniprot.org/uniprotkb/F1NVP8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "DNA polymerase binding", "id": "GO:0070182", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070182", "evidence": [ { "database": "UniProtKB", "id": "F1NVP8", "url": "https://www.uniprot.org/uniprotkb/F1NVP8" } ], "pmid": "" }, { "name": "DNA end binding", "id": "GO:0045027", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045027", "evidence": [ { "database": "UniProtKB", "id": "F1NVP8", "url": "https://www.uniprot.org/uniprotkb/F1NVP8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1NVP8-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 298, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1NVP8-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1NVP8" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1NVP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NVP8" }, { "id": "PF09302", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09302" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "XLF-like N-terminal", "eco_id": "ECO_0000259", "start_pos": 15, "end_pos": 126, "start_aa": "Pro", "end_aa": "Arg", "glycosite_overlap": "" }, { "evidence": [ { "id": "F1NVP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NVP8" }, { "id": "PF21928", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21928" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "XLF-like coiled-coil region", "eco_id": "ECO_0000259", "start_pos": 129, "end_pos": 177, "start_aa": "Pro", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1NVR6-1", "uniprot_ac": "F1NVR6", "uniprot_id": "F1NVR6_CHICK", "mass": { "chemical_mass": 101047.0, "monoisotopic_mass": 101047.0 }, "refseq": { "ac": "XP_015132180", "name": "N-alpha-acetyltransferase 15, NatA auxiliary subunit", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015132180" }, "gene_names": [ { "name": "NAA15", "type": "recommended", "evidence": [ { "id": "F1NVR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NVR6" } ] }, { "name": "NAA15", "type": "synonym", "evidence": [ { "id": "XP_015132180", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015132180" } ] } ], "protein_names": [ { "name": "N-alpha-acetyltransferase 15, NatA auxiliary subunit", "type": "synonym", "evidence": [ { "id": "XP_015132180", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015132180" }, { "id": "F1NVR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NVR6/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052535.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015132180", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015132180" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NVR6", "url": "https://www.uniprot.org/uniprotkb/F1NVR6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "NAA15", "url": "https://www.uniprot.org/uniprotkb/F1NVR6", "locus": { "chromosome": "4", "start_pos": 28882198, "end_pos": 28848891, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010010037", "url": "https://www.ensembl.org/id/ENSGALG00010010037" } ] } } ], "crossref": [ { "id": "F1NVR6", "url": "https://alphafold.ebi.ac.uk/entry/F1NVR6", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000009782", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000009782", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "422440", "url": "https://www.ncbi.nlm.nih.gov/gene/422440", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011990", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011990", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019734", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019734", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR021183", "url": "https://www.ebi.ac.uk/interpro/entry/IPR021183", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:422440", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422440", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MEMRADY", "url": "https://omabrowser.org/oma/group/MEMRADY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1NVR6", "url": "https://www.orthodb.org/?gene=F1NVR6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22767", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22767", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22767:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22767:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF12569", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12569", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13181", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13181", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015132180", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015132180", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1NVR6", "url": "https://www.uniprot.org/uniprotkb/F1NVR6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NVR6-1", "url": "https://www.uniprot.org/uniprotkb/F1NVR6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPSVSLPPKENALFKRILRCYEHKQYRNGLKFCKQILSNPKFAEHGETLAMKGLTLNCLGKKEEAYELVRRGLRNDLKSHVCWHVYGLLQRSDKKYDEAIKCYRNALKWDKDNLQILRDLSLLQIQMRDLEGYRETRYQLLQLRPAQRASWIGYAIAYHLLEDYEMAAKILEEFRKTQQTSPDKVDYEYSELLLYQNQVLREAGLHKEALEHLCTYEKQICDKLAVEETKGELLLQLGRLEEAVDVYKGLQERNPENWAYYKGLEKALKPANMMERLKIYEEAWTKYPKGLVPRRLPLNFLSGEKFKECLDKFLRMNFSKGCPPVFNTLRSLYKDKEKVAIIEELVVGYETSLRSCRLFNPNDDGKEEPPTTLLWVQYYLAQHYDKIGQPSLALEYINAAIESTPTLIELFLVKAKIYKHAGNIKEAARWMDEAQALDTADRFINSKCAKYMLKANFIKEAEEMCSKFTREGTSAVENLNEMQCMWFQTECAQAYKAMNKFGEALKKCHEIERHFVEITDDQFDFHTYCMRKITLRSYVDLLKLEDVLRQHPFYFKAARIAIEIYLKLHDNPLTDENKEHEADTANMSDKELKKLRNKQRRAQKKAQLEEEKKNAEKEKQQRNQKKKKDDDDEEIGGPKEELIPEKLAKVEAPLEEAIKFLTPLKNLVKNKIETHLFAFEIYFRKEKFLLMLQSVKRAFAIDSSHPWLHECMIHLFSSVSESKDLPDAVRTVLNQEMNRLFGATNPKNFNEAFLKKNYDSLPHRLSAAKMMYYLDPSSQKRAVELAMTLDESLINRNLQTCMEVLEALCDGSLGDCKEASETYRANCHKLFPYALAFMPPGYEEDMKITVNGDSSAEPEELANEI", "length": 865, "header": "tr|F1NVR6-1|F1NVR6_CHICK Isoform 1 of N-alpha-acetyltransferase 15, NatA auxiliary subunit OS=Gallus gallus OX=9031 GN=NAA15 PE=1 SV=3 CANONICAL=F1NVR6-1" }, "isoforms": [ { "isoform_ac": "F1NVR6-1", "url": "https://www.uniprot.org/uniprotkb/F1NVR6/entry#F1NVR6-1", "sequence": { "sequence": "MPSVSLPPKENALFKRILRCYEHKQYRNGLKFCKQILSNPKFAEHGETLAMKGLTLNCLGKKEEAYELVRRGLRNDLKSHVCWHVYGLLQRSDKKYDEAIKCYRNALKWDKDNLQILRDLSLLQIQMRDLEGYRETRYQLLQLRPAQRASWIGYAIAYHLLEDYEMAAKILEEFRKTQQTSPDKVDYEYSELLLYQNQVLREAGLHKEALEHLCTYEKQICDKLAVEETKGELLLQLGRLEEAVDVYKGLQERNPENWAYYKGLEKALKPANMMERLKIYEEAWTKYPKGLVPRRLPLNFLSGEKFKECLDKFLRMNFSKGCPPVFNTLRSLYKDKEKVAIIEELVVGYETSLRSCRLFNPNDDGKEEPPTTLLWVQYYLAQHYDKIGQPSLALEYINAAIESTPTLIELFLVKAKIYKHAGNIKEAARWMDEAQALDTADRFINSKCAKYMLKANFIKEAEEMCSKFTREGTSAVENLNEMQCMWFQTECAQAYKAMNKFGEALKKCHEIERHFVEITDDQFDFHTYCMRKITLRSYVDLLKLEDVLRQHPFYFKAARIAIEIYLKLHDNPLTDENKEHEADTANMSDKELKKLRNKQRRAQKKAQLEEEKKNAEKEKQQRNQKKKKDDDDEEIGGPKEELIPEKLAKVEAPLEEAIKFLTPLKNLVKNKIETHLFAFEIYFRKEKFLLMLQSVKRAFAIDSSHPWLHECMIHLFSSVSESKDLPDAVRTVLNQEMNRLFGATNPKNFNEAFLKKNYDSLPHRLSAAKMMYYLDPSSQKRAVELAMTLDESLINRNLQTCMEVLEALCDGSLGDCKEASETYRANCHKLFPYALAFMPPGYEEDMKITVNGDSSAEPEELANEI", "length": 865, "header": "tr|F1NVR6-1|F1NVR6_CHICK Isoform 1 of N-alpha-acetyltransferase 15, NatA auxiliary subunit OS=Gallus gallus OX=9031 GN=NAA15 PE=1 SV=3 CANONICAL=F1NVR6-1" }, "locus": { "chromosome": "4", "start_pos": 28880922, "end_pos": 28848938, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010023869.1", "url": "https://www.ensembl.org/id/ENSGALT00010023869.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010013645.1", "url": "https://www.ensembl.org/id/ENSGALP00010013645.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:422440", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422440", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZD89-1", "protein_name": "N(alpha)-acetyltransferase 15, NatA auxiliary subunit", "gene_name": "Naa15", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPAVSLPPKENALFKRILRCYEHKQYRNGLKFCKQILSNPKFAEHGETLAMKGLTLNCLGKKEEAYELVRRGLRNDLKSHVCWHVYGLLQRSDKKYDEAIKCYRNALKWDKDNLQILRDLSLLQIQMRDLEGYRETRYQLLQLRPAQRASWIGYAIAYHLLEDYEMAAKILEEFRKTQQTSPDKVDYEYSELLLYQNQVLREAGLYREALEHLCTYEKQICDKLAVEETKGELLLQLCRLEDAADVYRGLQERNPENWAYYKGLEKALKPANMLERLKIYEEAWTKFPRGLVPRRLPLNFLSGEKFKECLDRFLRMNFSKGCPPVFNTLRSLYRDKEKVAIVEELVVGYETSLKSCRLFNPNDDGKEEPPTTLLWVQYYLAQHYDKIGQPSIALEYINTAIESTPTLIELFLVKAKIYKHAGNIKEAARWMDEAQALDTADRFINSKCAKYMLKANLIKEAEEMCSKFTREGTSAVENLNEMQCMWFQTECAQAYKAMNKFGEALKKCHEIERHFIEITDDQFDFHTYCMRKITLRSYVDLLKLEDVLRQHPFYFKAARIAIEIYLKLHDNPLTDENKEHEADTANMSDKELKKLRNKQRRAQKKAQIEEEKKNAEKEKQQRNQKKKKDDDDEEIGGPKEELIPEKLAKVETPLEEAIKFLTPLKNLVKNKIETHLFAFEIYFRKEKFLLMLQSVKRAFAIDSSHPWLHECMIRLFNSVCESKDLPEAVRTVLKQEMNRLFGATNPKNFNETFLKRNSDSLPHRLSAAKMIYYLDSSSQKRAIELATTLDGSLTNRNLQTCMEVLEALCGGSLGDCKEAAEAYRVSCHKLFPYALAFMPPGYEEDMKITVNGDSSAETEELANEI", "length": 865 }, "evidence": [ { "id": "F1NVR6", "url": "https://omabrowser.org/oma/group/F1NVR6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P12945-1", "protein_name": "N-terminal acetyltransferase A complex subunit NAT1", "gene_name": "NAT1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSRKRSTKPKPAAKIALKKENDQFLEALKLYEGKQYKKSLKLLDAILKKDGSHVDSLALKGLDLYSVGEKDDAASYVANAIRKIEGASASPICCHVLGIYMRNTKEYKESIKWFTAALNNGSTNKQIYRDLATLQSQIGDFKNALVSRKKYWEAFLGYRANWTSLAVAQDVNGERQQAINTLSQFEKLAEGKISDSEKYEHSECLMYKNDIMYKAASDNQDKLQNVLKHLNDIEPCVFDKFGLLERKATIYMKLGQLKDASIVYRTLIKRNPDNFKYYKLLEVSLGIQGDNKLKKALYGKLEQFYPRCEPPKFIPLTFLQDKEELSKKLREYVLPQLERGVPATFSNVKPLYQRRKSKVSPLLEKIVLDYLSGLDPTQDPIPFIWTNYYLSQHFLFLKDFPKAQEYIDAALDHTPTLVEFYILKARILKHLGLMDTAAGILEEGRQLDLQDRFINCKTVKYFLRANNIDKAVEVASLFTKNDDSVNGIKDLHLVEASWFIVEQAEAYYRLYLDRKKKLDDLASLKKEVESDKSEQIANDIKENQWLVRKYKGLALKRFNAIPKFYKQFEDDQLDFHSYCMRKGTPRAYLEMLEWGKALYTKPMYVRAMKEASKLYFQMHDDRLKRKSDSLDENSDEIQNNGQNSSSQKKKAKKEAAAMNKRKETEAKSVAAYPSDQDNDVFGEKLIETSTPMEDFATEFYNNYSMQVREDERDYILDFEFNYRIGKLALCFASLNKFAKRFGTTSGLFGSMAIVLLHATRNDTPFDPILKKVVTKSLEKEYSENFPLNEISNNSFDWLNFYQEKFGKNDINGLLFLYRYRDDVPIGSSNLKEMIISSLSPLEPHSQNEILQYYL", "length": 854 }, "evidence": [ { "id": "F1NVR6", "url": "https://omabrowser.org/oma/group/F1NVR6/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q80UM3-1", "protein_name": "N-alpha-acetyltransferase 15, NatA auxiliary subunit", "gene_name": "Naa15", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPAVSLPPKENALFKRILRCYEHKQYRNGLKFCKQILSNPKFAEHGETLAMKGLTLNCLGKKEEAYELVRRGLRNDLKSHVCWHVYGLLQRSDKKYDEAIKCYRNALKWDKDNLQILRDLSLLQIQMRDLEGYRETRYQLLQLRPAQRASWIGYAIAYHLLEDYEMAAKILEEFRKTQQTSPDKVDYEYSELLLYQNQVLREAGLYREALEHLCTYEKQICDKLAVEETKGELLLQLCRLEDAADVYRGLQERNPGNWAYYKGLEKALKPANMLERLKIYEEAWTKYPRGLVPRRLPLNFLSGEKFKECLDRFLRMNFSKGCPPVFNTLRSLYRDKEKVAIVEELVVGYETSLKSCRLFNPNDDGKEEPPTTLLWVQYYLAQHYDKIGQPSIALEYINTAIESTPTLIELFLVKAKIYKHAGNIKEAARWMDEAQALDTADRFINSKCAKYVLKANLIKEAEEMCSKFTREGTSAVENLNEMQCMWFQTECAQAYKAMNKFGEALKKCHEIERHFIEITDDQFDFHTYCMRKITLRSYVDLLKLEDVLRQHPFYFKAARIAIEIYLKLHDNPLTDENKEHEADTANMSDKELKKLRNKQRRAQKKAQIEEEKKNAEKEKQQRNQKKKKDDDDEEIGGPKEELIPEKLAKVETPLEEAIKFLTPLKNLVKNKIETHLFAFEIYFRKEKFLLMLQSVKRAFAIDSGHPWLHECMIRLFHSVCESKDLPETVRTVLKQEMNRLFGATNPKNFNETFLKRNSDSLPHRLSAAKMVYYLDSSSQKRAIELATTLDGSLTNRNLQTCMEVLEALCDGSLGDCKEAAEAYRASCHKLFPYALAFMPPGYEEDMKITVNGDSSAETEELANEI", "length": 865 }, "evidence": [ { "id": "F1NVR6", "url": "https://omabrowser.org/oma/group/F1NVR6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q869X1-1", "protein_name": "Tetratricopeptide-like helical domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MAPPTKELTNKEITAIKGISKLFDDKKYSKGLKECNAILKNHPENPDASCFKSLILYNLEQQYEARENAIKTTKTLPTNSMAWHTLGYIYKLDKNYLDATTAFKNASKFNKESSQILKELAPLQLYSRDLEGLKETYATLLKLQPTHKPHWTGLVTTYQLMGQTKSALSVFERYLDTLEEKDLVGVKKTESLLYRVMLNFELEEYDQALDILVKNEKTIIDKLWAMSKHGDILLKKGELSAAEAKFKDLIKLNQDDLNVHKKLWESKNIRSLDNLSDEEISTLDSLYKELSSLYPKSLLIQKIPLLFLKDKQQFREHAVLYTKNFLSKGIPSLFNNLKCLYNNKEKVEILSQLFLDQLNSLKEKQQLLGSDEKESPSTVLWCLYYLAQHFDRINDYSTSLSYINQAIEHTPTCLDLYVVKAKLYKHQGDLQKAYEEYDRARNLDLADRYLNTKCALYALRNNDPDTAEAIFSLIKDETQTLLFNIQEFQCIWYERELGKTYLRAGDNARAIKLFNFVDKNHLEYLEDQMDFHNHINKKLTMRSYIEFLRWEDQVYQNKPYIATGKAHVKAYLNHQNKPEVMAPLKKVPAIKKPAPKPSQLEPKKDPNTGLTIPEDDDLNGKKFLVKQVNLMDSAQLILDNLLKNTNDIEIYSLACQVNTHQKKYLLVLKSLVKIKSINENSPCYYENLVDLMIKVSEDKEVSAIVKAAVEKQAGFSSDVESILANNQTYLEKLGDNVTAQHRFVVGKIIAKLSPSSLDKASELILNVQGETSWKQCADNLQSLSLVSSELTSKYREKLHEHFPIANYFQPKVEN", "length": 814 }, "evidence": [ { "id": "F1NVR6", "url": "https://omabrowser.org/oma/group/F1NVR6/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q8VZM1-1", "protein_name": "N-terminal acetyltransferase A complex auxiliary subunit NAA15", "gene_name": "NAA15", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MGASLPPKEANLFKLIVKSYETKQYKKGLKAADAILKKFPDHGETLSMKGLTLNCMDRKTEAYELVRLGVKNDIKSHVCWHVLGLLYRSDREYREAIKCYRNALRIDPDNLEILRDLSLLQAQMRDLSGFVETRQQLLTLKPNHRMNWIGFAVSQHLNANASKAVEILEAYEGTLEDDYPPENELIEHTEMILYKVSLLEESGSFDKALEELHKKEPKIVDKLSYKEQEVSLLSKVGRLEEANKLYRVLLSMNPDNYRYHEGLQKCLGLYSESGQYSSDQIEKLNALYQSLSEQYTRSSAVKRIPLDFLQDENFKEAVAKYIKPLLTKGVPSLFSDLSSLYDHPRKPDILEQLVVEMKHSIGTTGSFPGSDVKEPPSTLLWTLFFLAQHYDRRGQYDVALCKIDEAIAHTPTVIDLYSVKSRIMKHAGDLTAAAALADEARGMDLADRYINSECVKRMLQADQVPLAEKTAVLFTKEGDQLNNLHDMQCMWYDLASGDSYFRQGDLGRALKKFLAVEKHYADISEDQFDFHSYCLRKMTLRSYVDMLKFQDRLHSFPYFHKAAIRAIRCYLKLHDSPKSTAGEDEMSKLAPAQKKKIKKQKKAEARAKKEAESKSEESTASGASKSGKRNVKPVDPDPHGQKLIQVEEPMAEASKYLRLLQKHSPNSLETHLLSFEVNMRKQKFLLAFQAVKQLLKLGAENPDSHRSLVKFFLMTESISAPTTEAEKLRWRVLEAERPSISQLQNKSLMEANKEFLGRHEDSLVHRAAYAEMLYILDPSKKTEAIKIIEDSTNKVVQTNEALGQAREWKLKDCIAVHTLLDTVLLDSQAASRWKSRCAEYFPCSTHFEGKHCSLMPDSVYNSSRKSNENGDTPNHPMGQTELSDGQLEAFKSLSVAT", "length": 897 }, "evidence": [ { "id": "F1NVR6", "url": "https://omabrowser.org/oma/group/F1NVR6/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9BXJ9-1", "protein_name": "N-alpha-acetyltransferase 15, NatA auxiliary subunit", "gene_name": "NAA15", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPAVSLPPKENALFKRILRCYEHKQYRNGLKFCKQILSNPKFAEHGETLAMKGLTLNCLGKKEEAYELVRRGLRNDLKSHVCWHVYGLLQRSDKKYDEAIKCYRNALKWDKDNLQILRDLSLLQIQMRDLEGYRETRYQLLQLRPAQRASWIGYAIAYHLLEDYEMAAKILEEFRKTQQTSPDKVDYEYSELLLYQNQVLREAGLYREALEHLCTYEKQICDKLAVEETKGELLLQLCRLEDAADVYRGLQERNPENWAYYKGLEKALKPANMLERLKIYEEAWTKYPRGLVPRRLPLNFLSGEKFKECLDKFLRMNFSKGCPPVFNTLRSLYKDKEKVAIIEELVVGYETSLKSCRLFNPNDDGKEEPPTTLLWVQYYLAQHYDKIGQPSIALEYINTAIESTPTLIELFLVKAKIYKHAGNIKEAARWMDEAQALDTADRFINSKCAKYMLKANLIKEAEEMCSKFTREGTSAVENLNEMQCMWFQTECAQAYKAMNKFGEALKKCHEIERHFIEITDDQFDFHTYCMRKITLRSYVDLLKLEDVLRQHPFYFKAARIAIEIYLKLHDNPLTDENKEHEADTANMSDKELKKLRNKQRRAQKKAQIEEEKKNAEKEKQQRNQKKKKDDDDEEIGGPKEELIPEKLAKVETPLEEAIKFLTPLKNLVKNKIETHLFAFEIYFRKEKFLLMLQSVKRAFAIDSSHPWLHECMIRLFNTAVCESKDLSDTVRTVLKQEMNRLFGATNPKNFNETFLKRNSDSLPHRLSAAKMVYYLDPSSQKRAIELATTLDESLTNRNLQTCMEVLEALYDGSLGDCKEAAEIYRANCHKLFPYALAFMPPGYEEDMKITVNGDSSAEAEELANEI", "length": 866 }, "evidence": [ { "id": "F1NVR6", "url": "https://omabrowser.org/oma/group/F1NVR6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VWI2-1", "protein_name": "N(Alpha)-acetyltransferase 15/16, isoform A", "gene_name": "Naa15-16", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MPSSDPLPPKEGALFRKLLKCYELKQYKNGLKLAKQILSNPKYMEHGETLAMKGLTLNGLGRREEAYKYVRLGLRNDLRSHVCWHVYGLLQRSDKKYDEAIKCYRNALKWEKDNLQILKDLSLLQIQMRDLEGYKETRHHLFTLRPSQHASWIGFAMSYHLLGDYDMANSILETFSQSQTSIEAHDYRHSELLLYQNQILIESNRLQQAVDHLTKYQGQIVDKLAVRETMGDLYIKLQQQEKAVPIFESLIRRNPENVLYYEQYIAARQVTDSSAVVSIYRVFQEQYPRALCPRRLPLNIANGDEFRVVTDEYLRRGLRKGIPPLFVNVRTLHQIPERAAVIEELALQYFENLTRSGHFSREDADAGIPVEPASALVWTALFLAQHYDYMRDTDRALEYINVAIDHTPTLIELLITKGRIFKHAGDPVEAYVWLEEAQSMDTADRYINSKCAKYMLRANMVQEAEEICAKFTREGVSAMDNLNEMQCMWFQTECALAYQRMGRWGESLKKCHEVERHFAEIVEDQFDFHTYCMRKMTLRAYVGLLRLEDVLRQHPFYFKAAKCAIEVYIRLYDKPLKSETTIEEIDIENLPPSELKKLRSKQRKAKKKAELESAQAAQAQVKREQHQKSKQQANQETDPDAPQLDELVAEKLERTDDPLDKAIEFLKPLQQLAKERIETHLLAFELYYRKNKLLLMLQCIRRARAVDASHPVIHSCIIRFVKSLTSAAKEQPFNEHVQQVLEKATKELIGSKTPQQLNDEFIAKHNASILHLYEGARSLYELDNSKKAAAIKLVTSFNLAKLRLEEATKIYTALRDGDVFGECEAEAASYQQACHQRFQYARIFRNVEELEAQLQEKEAAKLRAEEEQQQLIHVDSSEPVSVLATAAAAS", "length": 890 }, "evidence": [ { "id": "F1NVR6", "url": "https://omabrowser.org/oma/group/F1NVR6/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1NVR6", "url": "https://www.uniprot.org/uniprotkb/F1NVR6" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F1NVR6", "url": "https://www.uniprot.org/uniprotkb/F1NVR6" } ], "pmid": "" }, { "name": "nuclear body", "id": "GO:0016604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016604", "evidence": [ { "database": "UniProtKB", "id": "F1NVR6", "url": "https://www.uniprot.org/uniprotkb/F1NVR6" } ], "pmid": "" }, { "name": "transcription regulator complex", "id": "GO:0005667", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005667", "evidence": [ { "database": "UniProtKB", "id": "F1NVR6", "url": "https://www.uniprot.org/uniprotkb/F1NVR6" } ], "pmid": "" }, { "name": "NatA complex", "id": "GO:0031415", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031415", "evidence": [ { "database": "UniProtKB", "id": "F1NVR6", "url": "https://www.uniprot.org/uniprotkb/F1NVR6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "positive regulation of DNA-templated transcription", "id": "GO:0045893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045893", "evidence": [ { "database": "UniProtKB", "id": "F1NVR6", "url": "https://www.uniprot.org/uniprotkb/F1NVR6" } ], "pmid": "" }, { "name": "protein maturation", "id": "GO:0051604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051604", "evidence": [ { "database": "UniProtKB", "id": "F1NVR6", "url": "https://www.uniprot.org/uniprotkb/F1NVR6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "ribosome binding", "id": "GO:0043022", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043022", "evidence": [ { "database": "UniProtKB", "id": "F1NVR6", "url": "https://www.uniprot.org/uniprotkb/F1NVR6" } ], "pmid": "" }, { "name": "acetyltransferase activity", "id": "GO:0016407", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016407", "evidence": [ { "database": "UniProtKB", "id": "F1NVR6", "url": "https://www.uniprot.org/uniprotkb/F1NVR6" } ], "pmid": "" }, { "name": "acetyltransferase activator activity", "id": "GO:0010698", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010698", "evidence": [ { "database": "UniProtKB", "id": "F1NVR6", "url": "https://www.uniprot.org/uniprotkb/F1NVR6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 317, "end_pos": 319, "annotation": "n_glycosylation_sequon" }, { "start_pos": 586, "end_pos": 588, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1NVR6-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 865, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1NVR6-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1NVR6" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 317, "end_pos": 319 }, { "start_pos": 586, "end_pos": 588 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_417455", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_417455" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NVX7", "url": "https://www.uniprot.org/uniprotkb/F1NVX7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TM9SF4", "url": "https://www.uniprot.org/uniprotkb/F1NVX7", "locus": { "chromosome": "20", "start_pos": 10471526, "end_pos": 10455392, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013289", "url": "https://www.ensembl.org/id/ENSGALG00010013289" } ] } } ], "crossref": [ { "id": "F1NVX7", "url": "https://alphafold.ebi.ac.uk/entry/F1NVX7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000006568", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000006568", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "419281", "url": "https://www.ncbi.nlm.nih.gov/gene/419281", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004240", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004240", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:419281", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419281", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "VVGFEVY", "url": "https://omabrowser.org/oma/group/VVGFEVY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YIU9", "url": "https://www.orthodb.org/?gene=A0A8V0YIU9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NVX7", "url": "https://www.orthodb.org/?gene=F1NVX7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10766", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10766", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10766:SF55", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10766:SF55", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02990", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02990", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_417455", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_417455", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YIU9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIU9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YIU9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIU9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NVX7", "url": "https://www.uniprot.org/uniprotkb/F1NVX7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NVX7-1", "url": "https://www.uniprot.org/uniprotkb/F1NVX7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MATDPAANRAPLPLTSAPTRGSKMAAAAAMVERLRYLLLLLLWLHGTDSFYVPGVAPINFHWNDPVEIKAVKLTSSRTQLPYEYYSLPFCQPTEITYKAENLGEVLRGDRIVNTPFQVFMNVEKKCEVLCNFPNKPVTLTVEQSKLMAERIREDYYVHLIADNLPVATRLEFYSNREEEEKKKEKDVQFEHGYRLGFLDGNKFYLHNHLSFILYYHREDVEENQEPTYRVVRFEVIPQSIKLEDLKADEKGMCTLPEATGSAPQEIDPSKENQLLFTYSVHWEESDIKWASRWDTYLTMSDVQIHWFSIINSVVVVFFLSGILSMIIIRTLRKDIANYNKEDDIEDTMEESGWKLVHGDVFRPPQYPMILSSLLGSGIQLFCMILIVIFVAMLGMLSPSSRGALMTTACFLFMFMGVFGGFFAGRLYRTLKGHRWKKGAFCTATLYPGVVFGICFVLNCFIWGEHSSGAVPFPTMVALLCMWFGISLPLVYLGYYFGFRKQPYDNPVRTNQIPRQIPEQRWYMNKFVGILMAGILPFGAMFIELFFIFSAIWENQFYYLFGFLFLVFIILVVSCSQISIVMVYFQLCAEDYRWWWRTFLVSGGSAFYVLIYAVFYFVNKLDIVEFIPSLLYFGYTALMVLSFWLLTGTIGFYAAYMFVRKIYAAVKID", "length": 668, "header": "tr|F1NVX7-1|F1NVX7_CHICK Isoform 1 of Transmembrane 9 superfamily member OS=Gallus gallus OX=9031 GN=TM9SF4 PE=1 SV=2 CANONICAL=F1NVX7-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YIU9-1", "url": "https://www.uniprot.org/uniprotkb/F1NVX7/entry#A0A8V0YIU9-1", "sequence": { "sequence": "MAAAAAMVERLRYLLLLLLWLHGTDSFYVPGVAPINFHWNDPVEIKAVKLTSSRTQLPYEYYSLPFCQPTEITYKAENLGEVLRGDRIVNTPFQVFMNVEKKCEVLCNFPNKPVTLTVEQSKLMAERIREDYYVHLIADNLPVATRLEFYSNREEEEKKKEKDVQFEHGYRLGFLDGNKFYLHNHLSFILYYHREDVEENQEPTYRVVRFEVIPQSIKLEDLKADEKGILSMIIIRTLRKDIANYNKEDDIEDTMEESGWKLVHGDVFRPPQYPMILSSLLGSGIQLFCMILIVIFVAMLGMLSPSSRGALMTTACFLFMFMGVFGGFFAGRLYRTLKGHRWKKGAFCTATLYPGVVFGICFVLNCFIWGEHSSGAVPFPTMVALLCMWFGISLPLVYLGYYFGFRKQPYDNPVRTNQIPRQIPEQRWYMNKFVGILMAGILPFGAMFIELFFIFSAIWENQFYYLFGFLFLVFIILVVSCSQISIVMVYFQLCAEDYRWWWRTFLVSGGSAFYVLIYAVFYFVNKLDIVEFIPSLLYFGYTALMVLSFWLLTGTIGFYAAYMFVRKIYAAVKID", "length": 575, "header": "tr|A0A8V0YIU9-1|A0A8V0YIU9_CHICK Computationally mapped isoform of Transmembrane 9 superfamily member OS=Gallus gallus OX=9031 GN=TM9SF4 PE=1 SV=1 CANONICAL=F1NVX7-1" }, "locus": { "chromosome": "20", "start_pos": 10469552, "end_pos": 10455542, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031956.1", "url": "https://www.ensembl.org/id/ENSGALT00010031956.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018748.1", "url": "https://www.ensembl.org/id/ENSGALP00010018748.1" } ] } }, { "isoform_ac": "F1NVX7-1", "url": "https://www.uniprot.org/uniprotkb/F1NVX7/entry#F1NVX7-1", "sequence": { "sequence": "MATDPAANRAPLPLTSAPTRGSKMAAAAAMVERLRYLLLLLLWLHGTDSFYVPGVAPINFHWNDPVEIKAVKLTSSRTQLPYEYYSLPFCQPTEITYKAENLGEVLRGDRIVNTPFQVFMNVEKKCEVLCNFPNKPVTLTVEQSKLMAERIREDYYVHLIADNLPVATRLEFYSNREEEEKKKEKDVQFEHGYRLGFLDGNKFYLHNHLSFILYYHREDVEENQEPTYRVVRFEVIPQSIKLEDLKADEKGMCTLPEATGSAPQEIDPSKENQLLFTYSVHWEESDIKWASRWDTYLTMSDVQIHWFSIINSVVVVFFLSGILSMIIIRTLRKDIANYNKEDDIEDTMEESGWKLVHGDVFRPPQYPMILSSLLGSGIQLFCMILIVIFVAMLGMLSPSSRGALMTTACFLFMFMGVFGGFFAGRLYRTLKGHRWKKGAFCTATLYPGVVFGICFVLNCFIWGEHSSGAVPFPTMVALLCMWFGISLPLVYLGYYFGFRKQPYDNPVRTNQIPRQIPEQRWYMNKFVGILMAGILPFGAMFIELFFIFSAIWENQFYYLFGFLFLVFIILVVSCSQISIVMVYFQLCAEDYRWWWRTFLVSGGSAFYVLIYAVFYFVNKLDIVEFIPSLLYFGYTALMVLSFWLLTGTIGFYAAYMFVRKIYAAVKID", "length": 668, "header": "tr|F1NVX7-1|F1NVX7_CHICK Isoform 1 of Transmembrane 9 superfamily member OS=Gallus gallus OX=9031 GN=TM9SF4 PE=1 SV=2 CANONICAL=F1NVX7-1" }, "locus": { "chromosome": "20", "start_pos": 10469552, "end_pos": 10455473, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031962.1", "url": "https://www.ensembl.org/id/ENSGALT00010031962.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018753.1", "url": "https://www.ensembl.org/id/ENSGALP00010018753.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:419281", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419281", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287BSC9-1", "protein_name": "Transmembrane 9 superfamily member", "gene_name": "TM9SF4", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAAGMDWFPWSLLLLSLTCDTGAFYVPGVAPINFHQNDPVEIKAVKLTSSRTQLPYEYYSLPFCQPSKITYKAENLGEVLRGDRIVNTPFQVFMNSEKKCEVLCSQSNKPVTLTVEQSRLVAERITEDYYVHLIADNLPVATRLELYSNRDGDDKKKEKDVQFEHGYRLGFTDVNKIYLHNHLSFILYYHREDLEEDQEHTYRVVRFEVIPQSIRLEDLKADEKGSCTLPEGTNSSPQEIDPTKENQLYFTYSVHWEESDIKWASRWDTYLTMSDVQIHWFSIINSVVVVFFLSGILSMIIIRTLRKDIANYNKEDDIEDTMEESGWKLVHGDVFRPPQYPMILSSLLGSGIQLFCMILIVIFVAMLGMLSPSSRGALMTTACFLFMFMGVFGGFSAGRLYRTLKGHRWKKGAFCTATLYPGVVFGICFVLNCFIWGKHSSGAVPFPTMVALLCMWFGISLPLVYLGYYFGFRKQPYDNPVRTNQIPRQIPEQRWYMNRFVGILMAGILPFGAMFIELFFIFSAIWENQFYYLFGFLFLVFIILVVSCSQISIVMVYFQLCAEDYRWWWRNFLVSGGSAFYVLVYAIFYFVNKLDIVEFIPSLLYFGYTALMVLSFWLLTGTIGFYAAYMFVRKIYAAVKID", "length": 642 }, "evidence": [ { "id": "F1NVX7", "url": "https://omabrowser.org/oma/group/F1NVX7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A5D7E2-1", "protein_name": "Transmembrane 9 superfamily member 4", "gene_name": "TM9SF4", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAAAMDWLPWSLLLFSLMCDTGAFYVPGVAPINFHQNDPVEIKAVKLTSSRTQLPYEYYSLPFCQPSKITYKAENLGEVLRGDRIVNTPFQVLMNSEKKCEVLCGQSNKPVTLTVEQSRLVAERISEDYYVHLIADNLPVATRLELYSNRDGDDKKKEKDVQFEHGYRLGFTDVNKIYLHNHLSFILYYHREDLEEDREHTYRVVRFEVIPQSVRLEDLKADEKSSCTLPEGTNSSPQEIDPTKENQLYFTYSVHWEESDIKWASRWDTYLTMSDVQIHWFSIINSVVVVFFLSGILSMIIIRTLRKDIANYNKEDDIEDTMEESGWKLVHGDVFRPPQYPMILSSLLGSGIQLFCMILIVIFVAMLGMLSPSSRGALMTTACFLFMFMGVFGGFSAGRLYRTLKGHRWKKGAFCTATLYPGVVFGICFVLNCFIWGKHSSGAVPFPTMVALLCMWFGISLPLVYLGYYFGFRKQPYDNPVRTNQIPRQIPEQRWYMNRFVGILMAGILPFGAMFIELFFIFSAIWENQFYYLFGFLFLVFIILVVSCSQISIVMVYFQLCAEDYRWWWRNFLVSGGSAFYVLVYAIFYFVNKLDIVEFIPSLLYFGYTALMVLSFWLLTGTIGFYAAYMFVRKIYAAVKID", "length": 642 }, "evidence": [ { "id": "F1NVX7", "url": "https://omabrowser.org/oma/group/F1NVX7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1Q4U1-1", "protein_name": "Transmembrane 9 superfamily member", "gene_name": "tm9sf4", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTRVFKMAAAMEMWALLLVSTLPCVAPFYVPGVAPMNFHQNSPVEIKAVKLTSSRTQLPYEYYSLPFCKPENIVYKAENLGEVLRGDRIVNTLYTVFMNLDKKCEVLCKKPESPIKLSVEESKLLAERIQEEYYIHLIADNLPVATRLELYPNKEEAIDEEQKKDTLKDVQFEHGYRLGFTENNKFYLHNHLSFILYFHKEKLEDAEEHNYRVVRFEVMPKSVKLEDIKADDRGTCTLPETVAPVPQEIDPSKENNILFTYSVHWQESEVKWASRWDTYLTMSDVQIHWFSIINSVVVVFFLSGILSMIIIRTLRKDIANYNREDDIEDTMEESGWKNVHGDVFRPPQYPMILSSLLGSGIQMFSMVLIVIFVAMLGMLSPSSRGALMTTACFLFMFMGLFGGYFAGRLYRTLKGHRWKKGAFCTATLYPAVVFGICFVLNCFIWGEHSSGAVPFTTMLALLCMWFGISLPLVYLGYYFGFRKQPYDNPVRTNQIPRQVPEQRWYMNKFVGILMAGILPFGAMFIELFFIFSAIWENQFYYLFGFLFLVFIILVVSCSQISIVMVYFQLCAEDYRWWWRTFLVSGGSAFYVLIYAIFYFVNKLDIVEFIPSLLYFGYTALMVLSFWLLTGTIGFYAAYVFIRKIYAAVKID", "length": 651 }, "evidence": [ { "id": "F1NVX7", "url": "https://omabrowser.org/oma/group/F1NVX7/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q4KLL4-1", "protein_name": "Transmembrane 9 superfamily member 4", "gene_name": "Tm9sf4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAAAMIWWPRFLLLLCLTCKGSTFYVPGVAPINFHQNDPVEIKAVKLTSSRTQLPYEYYSLPFCQPNKITYKAENLGEVLRGDRIVNTPFQVLMNSEKKCEVLCGQSNKPVILTVEQSRLVAERITEEYYVHLIADNLPVATRLELYSSNRDSDDKKKEKDVQFEHGYRLGFTDVNKIYLHNHLSFILYYHREDTEEDQEHTYRVVRFEVIPQSIRLEDLKIDEKSSCTLPEGANSLPQEIDPTKENQLYFTYSVHWEESDIKWASRWDTYLTMSDVQIHWFSIINSVVVVFFLSGILSMIIIRTLRKDIANYNKEDDIEDTMEESGWKLVHGDVFRPPQYPMILSSLLGSGIQLFCMILIVIFVAMLGMLSPSSRGALMTTACFLFMFMGVFGGFSAGRLYRTLKGHRWKKGAFCTATLYPGVVFGICFVLNCFIWGKHSSGAVPFPTMVALLCMWFGISLPLVYLGYYFGFRKQPYDNPVRTNQIPRQIPEQRWYMNRFVGILMAGILPFGAMFIELFFIFSAIWENQFYYLFGFLFLVFIILVVSCSQISIVMVYFQLCAEDYRWWWRNFLVSGGSAFYVLVYAIFYFVNKLDIVEFIPSLLYFGYTTLMVLSFWLLTGTIGFYAAYMFVRKIYAAVKID", "length": 643 }, "evidence": [ { "id": "F1NVX7", "url": "https://omabrowser.org/oma/group/F1NVX7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q55FP0-1", "protein_name": "Putative phagocytic receptor 1a", "gene_name": "phg1a", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKINKKQIVFFILFSIFLNHVNGIFYLPGMIPHDFAQGEEGAIKVNKITSVHTQIPYKYYQLPGVCQPKEGIIDDTENLGEILLGDRIENSDYTFNFLTDGGKCKVINSESCSPIIKKEDLKVLEDRIQNQYRVHWLLDGLPVRQTGRLASDPGFDLGFMTLAEGQTVATAEKYLNNHLEITIFYHSNPTDNTSRIVGFEIFPTSRQYKKVENWKGDTGDDCPQYGENFEQLSVSVKEGEDQERFVLWTYEVKYTPSPVLWNKRWDIYFESNDNSVHWFSILNSLMIVFILTVMVAMIIIRTLKKDIRRYTSIDTSEDRDSQEETGWKMIHGDVFRPPSHPMLLSVCIGSGVQIFSMTLITMIFAVLGFLSPANIGGLATALIVLFVLSAMFAGYFSTRVFTIFKGRNWKKNTIYTALSMPGIIFGIFFFVNMFLRGAKSSAAVPFGTFASIIAMWFGISVPLVFLGSYFASKKPVPEDPVRTNQIPRQVPDQIWYMNPYLSILMGGILPFGAVFIELHFILTSLWDNQFYYIFGFLFIVLMILIVTSAEISIVMCYFQLCAEDHHWWWRSFLTAGSSSLYMFIYSVSFFRYLGITKFISSLLDFSYSFIMSLAFAALTGTIGFYSCYFLVRKIYSSIHIN", "length": 641 }, "evidence": [ { "id": "F1NVX7", "url": "https://omabrowser.org/oma/group/F1NVX7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q8BH24-1", "protein_name": "Transmembrane 9 superfamily member 4", "gene_name": "Tm9sf4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAAMIWWPRFLLLLCLTCKGSTFYVPGVAPINFHQNDPVEIKAVKLTSSRTQLPYEYYSLPFCQPIKITYKAENLGEVLRGDRIVNTPFQVLMNSEKKCEVLCNQSNKPITLTVEQSRLVAERITEEYYVHLIADNLPVATRLELYSSNRDSDDKKKEKDVQFEHGYRLGFTDVNKIYLHNHLSFILYYHREDMEEDQEHTYRVVRFEVIPQSIRLEDLKTGEKSSCTLPEGANSLPQEIDPTKENQLYFTYSVHWEESDIKWASRWDTYLTMSDVQIHWFSIINSVVVVFFLSGILSMIIIRTLRKDIANYNKEDDIEDTMEESGWKLVHGDVFRPPQYPMILSSLLGSGIQLFCMILIVIFVAMLGMLSPSSRGALMTTACFLFMFMGVFGGFSAGRLYRTLKGHRWKKGAFCTATLYPGVVFGICFVLNCFIWGKHSSGAVPFPTMVALLCMWFGISLPLVYLGYYFGFRKQPYDNPVRTNQIPRQIPEQRWYMNRFVGILMAGILPFGAMFIELFFIFSAIWENQFYYLFGFLFLVFIILVVSCSQISIVMVYFQLCAEDYRWWWRNFLVSGGSAFYVLVYAIFYFVNKLDIVEFIPSLLYFGYTTLMVLSFWLLTGTIGFYAAYMFVRKIYAAVKID", "length": 643 }, "evidence": [ { "id": "F1NVX7", "url": "https://omabrowser.org/oma/group/F1NVX7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8RWW1-1", "protein_name": "Transmembrane 9 superfamily member 10", "gene_name": "TMN10", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MAKVRILIFTLVLFFSLNVHIHGFYLPGVAPQDFQMGDALMVKVNKLTSTKTQLPYSYYSLPYCRPEHIVDSAENLGEVLRGDRIENSPFVFKMRESQMCAAVCRVKLDKKTAKAFKEKIADEYRVNMILDNLPLVVPVQRPDQDNVVVYQHGFHVGLKGIFAGKKEEKYFIHNHLTFTVRYHRDIQTDSSRIVGFEVKPFSVKHEYEGQWNEKARLTTCDPHTKRAVTNSESPQEVEEGNEIIFTYDVDFQESEVKWASRWDTYLLMADDQIHWFSIVNSMMIVLFLSGMVAMIMLRTLYRDISNYNQLESHEEALEETGWKLVHGDVFRPPTNPELLCVYAGTGVQCFGMILVTMIFACLGFLSPSNRGGLMTAMLLLWVFMGLLAGYASSRLYKTLRGTEWKRNALKTAFMFPATVFVAFFVLNAIIWGQKSSGAVPFGTMFALVVLWFGISVPLVFIGGYIGFRKPAPEDPVKTNKIPRQIPTQAWYMNPIFSILIGGILPFGAVFIELFFILTSIWLHQFYYIFGFLFIVFIILIITCAEITVVLCYFQLCSEDYQWWWRSYLTSGSSAVYLFLYAVFYFYTKLEITKLVSAVLYFGYMLIVSYVFFVFTGAIGFYACFWFTRLIYSSVKID", "length": 637 }, "evidence": [ { "id": "F1NVX7", "url": "https://omabrowser.org/oma/group/F1NVX7/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q92544-1", "protein_name": "Transmembrane 9 superfamily member 4", "gene_name": "TM9SF4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MATAMDWLPWSLLLFSLMCETSAFYVPGVAPINFHQNDPVEIKAVKLTSSRTQLPYEYYSLPFCQPSKITYKAENLGEVLRGDRIVNTPFQVLMNSEKKCEVLCSQSNKPVTLTVEQSRLVAERITEDYYVHLIADNLPVATRLELYSNRDSDDKKKEKDVQFEHGYRLGFTDVNKIYLHNHLSFILYYHREDMEEDQEHTYRVVRFEVIPQSIRLEDLKADEKSSCTLPEGTNSSPQEIDPTKENQLYFTYSVHWEESDIKWASRWDTYLTMSDVQIHWFSIINSVVVVFFLSGILSMIIIRTLRKDIANYNKEDDIEDTMEESGWKLVHGDVFRPPQYPMILSSLLGSGIQLFCMILIVIFVAMLGMLSPSSRGALMTTACFLFMFMGVFGGFSAGRLYRTLKGHRWKKGAFCTATLYPGVVFGICFVLNCFIWGKHSSGAVPFPTMVALLCMWFGISLPLVYLGYYFGFRKQPYDNPVRTNQIPRQIPEQRWYMNRFVGILMAGILPFGAMFIELFFIFSAIWENQFYYLFGFLFLVFIILVVSCSQISIVMVYFQLCAEDYRWWWRNFLVSGGSAFYVLVYAIFYFVNKLDIVEFIPSLLYFGYTALMVLSFWLLTGTIGFYAAYMFVRKIYAAVKID", "length": 642 }, "evidence": [ { "id": "F1NVX7", "url": "https://omabrowser.org/oma/group/F1NVX7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9V3N6-1", "protein_name": "Transmembrane 9 superfamily member", "gene_name": "TM9SF4", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MQSGALARPCLAIVLLAGVVLVADSFYVPGVAPVEFVQDQKIDVKAVKMTSSRTQLPYQYYSLRFCYPKNGTLIFKSENLGEVLRGDRIVNTPYEVRMNQQVNCRLLCNQKDRPLTWSKEDSALVAERIQHEYFVHLLVDNLPVATRIVSVNNPAEVTYEHGYRLGQVDGDNIYINNHLKFILSYHMHSKDKYRVVGFEVETVSVSHKELKFHGDTCNFPDSARPQLVNPNGETQLYFTYSVEWKESKVSWASRWDIYLGMRDVQIHWFSIINSLVVVFFLSGILTMIMIRTLRRDIARYNTDDNIEDTLEETGWKLVHGDVFRPPKNTRLFSAIIGSGIQIFFMALITIFFAMLGMLSPSSRGALMTSGIFMYVFMGTIAGYYAARLYKTMKGREWKRAAFLTATLYPGIVFGTGFFLNFFIWDKSSSGAVPFTTMISLLLLWFGISVPLVYLGFYLGYRKQPYQHPVRTNMIPRQVPTQHWYMNAVLSTLMAGILPFGAVFIELFFVFTAIWQNQFYYLFGFLFLVFCILVVSCAQISIVMTYFQLCGEDYRWWWRSFVVSGGSAVYVLFYSIFYFFTKLEITEFIPTLLYLGYTGLMVLTFWLLTGSIGFFAAYVFILRIYGAVKID", "length": 630 }, "evidence": [ { "id": "F1NVX7", "url": "https://omabrowser.org/oma/group/F1NVX7/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "early endosome", "id": "GO:0005769", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005769", "evidence": [ { "database": "UniProtKB", "id": "F1NVX7", "url": "https://www.uniprot.org/uniprotkb/F1NVX7" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "F1NVX7", "url": "https://www.uniprot.org/uniprotkb/F1NVX7" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "F1NVX7", "url": "https://www.uniprot.org/uniprotkb/F1NVX7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 8, "go_terms": [ { "name": "cell adhesion", "id": "GO:0007155", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007155", "evidence": [ { "database": "UniProtKB", "id": "F1NVX7", "url": 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Component", "total": 5, "go_terms": [ { "name": "spindle pole", "id": "GO:0000922", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000922", "evidence": [ { "database": "UniProtKB", "id": "F1NVZ6", "url": "https://www.uniprot.org/uniprotkb/F1NVZ6" } ], "pmid": "" }, { "name": "cytoplasmic dynein complex", "id": "GO:0005868", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005868", "evidence": [ { "database": "UniProtKB", "id": "F1NVZ6", "url": "https://www.uniprot.org/uniprotkb/F1NVZ6" } ], "pmid": "" }, { "name": "ciliary base", "id": "GO:0097546", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097546", "evidence": [ { "database": "UniProtKB", "id": "F1NVZ6", "url": "https://www.uniprot.org/uniprotkb/F1NVZ6" } ], "pmid": "" }, { "name": "interphase microtubule organizing center", "id": "GO:0031021", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031021", "evidence": [ { "database": "UniProtKB", "id": "F1NVZ6", "url": "https://www.uniprot.org/uniprotkb/F1NVZ6" } ], "pmid": "" }, { 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{ "start_pos": 818, "end_pos": 820 }, { "start_pos": 919, "end_pos": 921 }, { "start_pos": 994, "end_pos": 996 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": 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"count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { 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"UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NW51/entry#names_and_taxonomy" } ] }, { "name": "2.8.2.-", "type": "synonym", "evidence": [ { "id": "F1NW51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NW51/entry#names_and_taxonomy" } ] }, { "name": "heparan sulfate glucosamine 3-O-sulfotransferase 4", "type": "synonym", "evidence": [ { "id": "XP_015149991", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015149991" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052545.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On May 17, 2018 this sequence version replaced XP_015149991.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015149991", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015149991" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NW51", "url": "https://www.uniprot.org/uniprotkb/F1NW51" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "HS3ST4", "url": "https://www.uniprot.org/uniprotkb/F1NW51", "locus": { "chromosome": "14", "start_pos": 7150557, "end_pos": 7106502, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010017315", "url": "https://www.ensembl.org/id/ENSGALG00010017315" } ] } } ], "crossref": [ { "id": "F1NW51", "url": "https://alphafold.ebi.ac.uk/entry/F1NW51", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000006290", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000006290", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "427674", "url": "https://www.ncbi.nlm.nih.gov/gene/427674", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000863", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000863", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037359", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037359", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:427674", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427674", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DWYRDVM", "url": "https://omabrowser.org/oma/group/DWYRDVM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1NW51", "url": "https://www.orthodb.org/?gene=F1NW51", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10605", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10605", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10605:SF11", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10605:SF11", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00685", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00685", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-2022928", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2022928", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_015149991", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015149991", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1NW51", "url": "https://www.uniprot.org/uniprotkb/F1NW51", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NW51-1", "url": "https://www.uniprot.org/uniprotkb/F1NW51-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAPPAQPGVPGGRGSKVPPARKLLCMCSLSLCLTYLCYSLMGGAGPAALRSPAAIPATAAPGAPRSPAALPGTAAPRSPPGPPGSAAAPTASAAPPRASNGSRDAGAWTRTPLAPGEVIAAQSGAFERDPQESSTTDEELSRAGSRGTTPDYGEKRLPQALIIGVKKGGTRALLEAIRAHPDVRAVGTEPHFFDRNYEKGLQWYRDVMPKTLEGQITMEKTPSYFVTNEAPRRIHSMAKDTKLIVVVRNPVTRAISDYTQTLSKKPEIPTFEVLAFKNRTLGLIDASWSAIRIGIYALHLENWLQYFPLSQILFVSGERLITDPAGEMAKVQDFLGLKRIVTEKHFYFNKTKGFPCLKKPEDSSAPRCLGKSKGRTHPKIDPDVIHRLRKFYKPFNVMFYQMTGQDFEWEREESEK", "length": 416, "header": "tr|F1NW51-1|F1NW51_CHICK Isoform 1 of Sulfotransferase OS=Gallus gallus OX=9031 GN=HS3ST4 PE=3 SV=4 CANONICAL=F1NW51-1" }, "isoforms": [ { "isoform_ac": "F1NW51-1", "url": "https://www.uniprot.org/uniprotkb/F1NW51/entry#F1NW51-1", "sequence": { "sequence": "MAPPAQPGVPGGRGSKVPPARKLLCMCSLSLCLTYLCYSLMGGAGPAALRSPAAIPATAAPGAPRSPAALPGTAAPRSPPGPPGSAAAPTASAAPPRASNGSRDAGAWTRTPLAPGEVIAAQSGAFERDPQESSTTDEELSRAGSRGTTPDYGEKRLPQALIIGVKKGGTRALLEAIRAHPDVRAVGTEPHFFDRNYEKGLQWYRDVMPKTLEGQITMEKTPSYFVTNEAPRRIHSMAKDTKLIVVVRNPVTRAISDYTQTLSKKPEIPTFEVLAFKNRTLGLIDASWSAIRIGIYALHLENWLQYFPLSQILFVSGERLITDPAGEMAKVQDFLGLKRIVTEKHFYFNKTKGFPCLKKPEDSSAPRCLGKSKGRTHPKIDPDVIHRLRKFYKPFNVMFYQMTGQDFEWEREESEK", "length": 416, "header": "tr|F1NW51-1|F1NW51_CHICK Isoform 1 of Sulfotransferase OS=Gallus gallus OX=9031 GN=HS3ST4 PE=3 SV=4 CANONICAL=F1NW51-1" }, "locus": { "chromosome": "14", "start_pos": 7149553, "end_pos": 7106502, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010041746.1", "url": "https://www.ensembl.org/id/ENSGALT00010041746.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024415.1", "url": "https://www.ensembl.org/id/ENSGALP00010024415.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 90, "start_aa": "Thr", "end_pos": 90, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr90", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:427674", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427674", "resource": "KEGG Pathway" }, { "id": "R-GGA-2022928", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2022928", "resource": "Reactome", "description": "HS-GAG biosynthesis" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I5ZUU3-1", "protein_name": "Sulfotransferase", "gene_name": "Hs3st4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MARWPAPPPPPPPPPPLAAPPPVPGASTKGPPARKLLFMCTLSLSVTYLCYSLLGGSGSLQFPLALQEPPGSAAEPPPSLPPPSLPPPGVRPGASSPPPDNASRGPPPEPPERFTTPAADGWGLASGGGARDAWPRSPPAPGDAVTEQDALLGRGAQELGAAEELEGRRAANGSAERGPASTPDYGEKKLPQALIIGVKKGGTRALLEAIRVHPDVRAVGVEPHFFDRNYEKGLEWYRNVMPKTLDGQITMEKTPSYFVTNEAPKRIHSMAKDIKLIVVVRNPVTRAISDYTQTLSKKPEIPTFEVLAFKNRTLGLIDASWSAIRIGIYALHLENWLQYFPLSQILFVSGERLIVDPAGEMAKVQDFLGLKRVVTEKHFYFNKTKGFPCLKKPEDSSAPRCLGKSKGRTHPRIDPDVIHRLRKFYKPFNMMFYQMTGQDFQWEQEEGDK", "length": 449 }, "evidence": [ { "id": "F1NW51", "url": "https://omabrowser.org/oma/group/F1NW51/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3YVV6-1", "protein_name": "Sulfotransferase", "gene_name": "Hs3st4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MARWPAPPPPPPPPPPLAAPPLLPGASTKGPPARKLLFMCTLSLSVTYLCYSLLGGSGSLQFPLALQEPPGSAAEPPPSLLSPSLPPPRVRPGASSPPPDNASRGPPPEPPERFTTPAADGWGLASGGGARDAWPRSPPAPGDAVTEQDALLGRGAQEPGAAEELEGRRAANGSAERGPASTPDYGEKKLPQALIIGVKKGGTRALLEAIRVHPDVRAVGVEPHFFDRNYEKGLEWYRNVMPKTLDGQITMEKTPSYFVTNEAPKRIHSMAKDIKLIVVVRNPVTRAISDYTQTLSKKPEIPTFEVLAFKNRTLGLIDASWSAIRIGIYALHLENWLQYFPLSQILFVSGERLIVDPAGEMAKVQDFLGLKRVVTEKHFYFNKTKGFPCLKKPEDSSAPRCLGKSKGRTHPRIDPDVIHRLRKFYKPFNMMFYQMTGQDFQWEQEEGDK", "length": 449 }, "evidence": [ { "id": "F1NW51", "url": "https://omabrowser.org/oma/group/F1NW51/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F1QME4-1", "protein_name": "Sulfotransferase", "gene_name": "hs3st4", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAFWSSTSVFTSKVPRKILFMFTLSLSVTYLFYSLMSCYNSFQFQENYVYQGRLVTEETTFVTLREKLYSSSSQGYLDEEFVERTATEQSLAISSVRNSAGIDERTPAWARAQAATTSSLSRAAAAAGEREHLEFSTTDSELRRVVNCTSDYGEKKLPQAIIIGVKKGGTRALLEALRVHPDVRAVGNEPHFFDRNYEKGLDWYRELMPSTLEGQITMEKTPSYFVTNSAPKRIHTMARDIKLIIVVRNPVTRAISDYTQTLSKRPEIPTFEVLAFKNRTLGLIDASWSALRIGIYALHLESWMQYFPLSQMHFVSGERLIVDPAGEMAKVQDFLGLKRIVTDKHFYFNKTKGFPCLKKPEDSSTPRCLGKSKGRTHPKIDPDVIRRLHKFYKPFNMMFYQMTGQNFQWELEEDGNSPGSRD", "length": 422 }, "evidence": [ { "id": "F1NW51", "url": "https://omabrowser.org/oma/group/F1NW51/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q9Y661-1", "protein_name": "Heparan sulfate glucosamine 3-O-sulfotransferase 4", "gene_name": "HS3ST4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MARWPAPPPPPPPPPPLAAPPPPGASAKGPPARKLLFMCTLSLSVTYLCYSLLGGSGSLQFPLALQESPGAAAEPPPSPPPPSLLPTPVRLGAPSQPPAPPPLDNASHGEPPEPPEQPAAPGTDGWGLPSGGGGAQDAWLRTPLAPSEMITAQSALPEREAQESSTTDEDLAGRRAANGSSERGGAVSTPDYGEKKLPQALIIGVKKGGTRALLEAIRVHPDVRAVGVEPHFFDRNYEKGLEWYRNVMPKTLDGQITMEKTPSYFVTNEAPKRIHSMAKDIKLIVVVRNPVTRAISDYTQTLSKKPEIPTFEVLAFKNRTLGLIDASWSAIRIGIYALHLENWLQYFPLSQILFVSGERLIVDPAGEMAKVQDFLGLKRVVTEKHFYFNKTKGFPCLKKPEDSSAPRCLGKSKGRTHPRIDPDVIHRLRKFYKPFNLMFYQMTGQDFQWEQEEGDK", "length": 456 }, "evidence": [ { "id": "F1NW51", "url": "https://omabrowser.org/oma/group/F1NW51/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "heparan sulfate proteoglycan biosynthetic process", "id": "GO:0015012", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015012", "evidence": [ { "database": "UniProtKB", "id": "F1NW51", "url": "https://www.uniprot.org/uniprotkb/F1NW51" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "[heparan sulfate]-glucosamine 3-sulfotransferase activity", "id": "GO:0008467", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008467", "evidence": [ { "database": "UniProtKB", "id": "F1NW51", "url": "https://www.uniprot.org/uniprotkb/F1NW51" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 100, "end_pos": 102, "annotation": "n_glycosylation_sequon" }, { "start_pos": 278, "end_pos": 280, "annotation": "n_glycosylation_sequon" }, { "start_pos": 349, "end_pos": 351, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-GGA-2076611", "name": "HS3ST2-6 sulfate GlcN at C3 in heparan sulfate", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "Golgi lumen, Golgi membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V1AQB3-1", "F1NL56-1", "F1NW51-1", "A0A8V0Z1U8-1", "A0A8V0ZEP2-1", "R4GJI3-1" ], "evidence": [ { "id": "R-GGA-2076611", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2076611" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A8V0Z1U8", "gene_name": "", "activity": [ { "ec_number": "2.8.2.-", "activity": "", "evidence": [ { "id": "A0A8V0Z1U8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1U8" } ] } ] }, { "uniprot_ac": "A0A8V0ZEP2", "gene_name": "HS3ST6", "activity": [ { "ec_number": "2.8.2.-", "activity": "", "evidence": [ { "id": "A0A8V0ZEP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEP2" } ] } ] }, { "uniprot_ac": "A0A8V1AQB3", "gene_name": "HS3ST3B1L", "activity": [ { "ec_number": "2.8.2.-", "activity": "", "evidence": [ { "id": "A0A8V1AQB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AQB3" } ] } ] }, { "uniprot_ac": "F1NL56", "gene_name": "HS3ST3A1", "activity": [ { "ec_number": "2.8.2.-", "activity": "", "evidence": [ { "id": "F1NL56", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NL56" } ] } ] }, { "uniprot_ac": "F1NW51", "gene_name": "HS3ST4", "activity": [ { "ec_number": "2.8.2.-", "activity": "", "evidence": [ { "id": "F1NW51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NW51" } ] } ] }, { "uniprot_ac": "R4GJI3", "gene_name": "HS3ST5", "activity": [ { "ec_number": "2.8.2.-", "activity": "", "evidence": [ { "id": "R4GJI3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GJI3" } ] } ] } ], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1NW51-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 416, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1NW51-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1NW51" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1NW51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NW51" }, { "id": "PF00685", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00685" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Sulfotransferase", "eco_id": "ECO_0000259", "start_pos": 158, "end_pos": 393, "start_aa": "Pro", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 90 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 100, "end_pos": 102 }, { "start_pos": 278, "end_pos": 280 }, { "start_pos": 349, "end_pos": 351 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1NW60-1", "uniprot_ac": "F1NW60", "uniprot_id": "F1NW60_CHICK", "mass": { "chemical_mass": 22852.0, "monoisotopic_mass": 22852.0 }, "refseq": { "ac": "NP_001012621", "name": "DNA replication complex GINS protein PSF1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012621" }, "gene_names": [ { "name": "GINS1", "type": "recommended", "evidence": [ { "id": "F1NW60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NW60" } ] }, { "name": "GINS1", "type": "synonym", "evidence": [ { "id": "NP_001012621", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012621" } ] } ], "protein_names": [ { "name": "DNA replication complex GINS protein PSF1", "type": "recommended", "evidence": [ { "id": "F1NW60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NW60/entry#names_and_taxonomy" } ] }, { "name": "DNA replication complex GINS protein PSF1", "type": "synonym", "evidence": [ { "id": "NP_001012621", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012621" } ] }, { "name": "GINS complex subunit 1 (Psf1 homolog)", "type": "synonym", "evidence": [ { "id": "NP_001012621", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012621" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ851817.1, CR389376.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000062.1. On Sep 23, 2021 this sequence version replaced NP_001012621.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001012621", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012621" } ] }, { "annotation": "Required for correct functioning of the GINS complex, a complex that plays an essential role in the initiation of DNA replication, and progression of DNA replication forks. GINS complex seems to bind preferentially to single-stranded DNA.", "evidence": [ { "database": "UniProtKB", "id": "F1NW60", "url": "https://www.uniprot.org/uniprotkb/F1NW60#function" }, { "database": "UniProtKB", "id": "RU368085", "url": "https://www.uniprot.org/uniprotkb/RU368085#function" }, { "database": "UniProtKB", "id": "ARBA00045258", "url": "https://www.uniprot.org/uniprotkb/ARBA00045258#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NW60", "url": "https://www.uniprot.org/uniprotkb/F1NW60" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "GINS1", "url": "https://www.uniprot.org/uniprotkb/F1NW60", "locus": { "chromosome": "3", "start_pos": 16095734, "end_pos": 16092785, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010016952", "url": "https://www.ensembl.org/id/ENSGALG00010016952" } ] } } ], "crossref": [ { "id": "F1NW60", "url": "https://alphafold.ebi.ac.uk/entry/F1NW60", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000008538", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000008538", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd11710", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11710", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd21696", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd21696", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "425297", "url": "https://www.ncbi.nlm.nih.gov/gene/425297", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR005339", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005339", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR021151", "url": "https://www.ebi.ac.uk/interpro/entry/IPR021151", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036224", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036224", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:425297", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:425297", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MFCEKAT", "url": "https://omabrowser.org/oma/group/MFCEKAT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1NW60", "url": "https://www.orthodb.org/?gene=F1NW60", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12914", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12914", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12914:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12914:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05916", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05916", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24997", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24997", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001012621", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012621", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1NW60", "url": "https://www.uniprot.org/uniprotkb/F1NW60", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NW60-1", "url": "https://www.uniprot.org/uniprotkb/F1NW60-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAGERAVGLVRELQSAAGGRLPPFRAEELRQTLEEMRTLYERNQADVSEAKSGRTDLIFLIRFRHCCLLRNQRCIVAYLYDRLLRIRALRWEYGSILPNTIQFHMAAEEVEWFNRYKKSLATYMRSVGGEEGLDLTQDIKPPKSLYIEVRCLRDYGEFEIDDGTTVLLKKNSQHFLPRWKCEQLIRQGVLEHILS", "length": 195, "header": "tr|F1NW60-1|F1NW60_CHICK Isoform 1 of DNA replication complex GINS protein PSF1 OS=Gallus gallus OX=9031 GN=GINS1 PE=3 SV=1 CANONICAL=F1NW60-1" }, "isoforms": [ { "isoform_ac": "F1NW60-1", "url": "https://www.uniprot.org/uniprotkb/F1NW60/entry#F1NW60-1", "sequence": { "sequence": "MAGERAVGLVRELQSAAGGRLPPFRAEELRQTLEEMRTLYERNQADVSEAKSGRTDLIFLIRFRHCCLLRNQRCIVAYLYDRLLRIRALRWEYGSILPNTIQFHMAAEEVEWFNRYKKSLATYMRSVGGEEGLDLTQDIKPPKSLYIEVRCLRDYGEFEIDDGTTVLLKKNSQHFLPRWKCEQLIRQGVLEHILS", "length": 195, "header": "tr|F1NW60-1|F1NW60_CHICK Isoform 1 of DNA replication complex GINS protein PSF1 OS=Gallus gallus OX=9031 GN=GINS1 PE=3 SV=1 CANONICAL=F1NW60-1" }, "locus": { "chromosome": "3", "start_pos": 16095285, "end_pos": 16092800, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010040935.1", "url": "https://www.ensembl.org/id/ENSGALT00010040935.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023899.1", "url": "https://www.ensembl.org/id/ENSGALP00010023899.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:425297", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:425297", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A1P8AW53-1", "protein_name": "Partner of SLD five 1", "gene_name": "PSF1", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MYGRKGYQLIKDFATGEKGQLKPFNSKLFDETIEECDQNHHLIQSLIRKMQQEGLDVQNNRNADHYGALIHHLALIRNKRCLMAYVYNRAEIVRDLAWRVGLELLDLPSEIQEKLTTLEKEYFKNHSVALKSYMGKVGIELNVDMVPPKDPYIKVRILDDIDEGIVLSDKTTNFARHSMHFLKRTDAEPYIARVSLFRYSFPKTRMI", "length": 207 }, "evidence": [ { "id": "F1NW60", "url": "https://omabrowser.org/oma/group/F1NW60/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "A0A286ZXR4-1", "protein_name": "DNA replication complex GINS protein PSF1", "gene_name": "GINS1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MLCEKAMELVRELHRAAEGQLPAFNEDGLRQVLEEMKALYEQNQSDVNEAKSGGRSDLIPTIKFRHCSLLRNQRCTIAYLYDRLLRIRALRWEYGSVLPNALRFHMSAEEMDWFNHYKKSLATYMRSLGGDEGLDITQDMKPPKSLYIEVRCLKDYGEFEVDDGTSVLLKKNSQHFLPRWKCEQLIRQGILEHVLS", "length": 196 }, "evidence": [ { "id": "F1NW60", "url": "https://omabrowser.org/oma/group/F1NW60/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A4IFH4-1", "protein_name": "DNA replication complex GINS protein PSF1", "gene_name": "GINS1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MFCEKAMELVRELHRAAEGRLPAFNEDGLRQVLEEMKALYEQNQSDVNEAKSSGRGDLIPTIKFRHCSLLRNQRCTVAYLYDRLLRIRALRWEYGSVLPSALRFHMSAEEMDWFNRYKKSLATYMRSLGGDEGLDITQDMKPPKSLYIEVRCLKDYGEFEVEDGTSVLLKKNSQHFLPRWKCEQLIRQGILEHVLS", "length": 196 }, "evidence": [ { "id": "F1NW60", "url": "https://omabrowser.org/oma/group/F1NW60/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q12488-1", "protein_name": "DNA replication complex GINS protein PSF1", "gene_name": "PSF1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MYGDLGNKLVLEAKRTKQLYARSNQDVNLPMYHEDIIRNILKEVSNLRKNTEYLKEQQQLGMLDDKVAKCQYFVTLLCMERNKRCLLAYQRLRTDILDSMAWNNNGLDLMSSITFSQQDTNNLSHQEQEYLKEYCDLITDLKSGDLVDIDLSGSLVPPSDVFIDVRVLKDAGEIQTEYGVFNLIKDSQFFVRQSDVERLIQQGYLQKI", "length": 208 }, "evidence": [ { "id": "F1NW60", "url": "https://omabrowser.org/oma/group/F1NW60/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q14691-1", "protein_name": "DNA replication complex GINS protein PSF1", "gene_name": "GINS1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MFCEKAMELIRELHRAPEGQLPAFNEDGLRQVLEEMKALYEQNQSDVNEAKSGGRSDLIPTIKFRHCSLLRNRRCTVAYLYDRLLRIRALRWEYGSVLPNALRFHMAAEEMEWFNNYKRSLATYMRSLGGDEGLDITQDMKPPKSLYIEVRCLKDYGEFEVDDGTSVLLKKNSQHFLPRWKCEQLIRQGVLEHILS", "length": 196 }, "evidence": [ { "id": "F1NW60", "url": "https://omabrowser.org/oma/group/F1NW60/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q54HR6-1", "protein_name": "Probable DNA replication complex GINS protein PSF1", "gene_name": "gins1", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MFTKTAIELIKELRGTDSIPHYNDTSIKATIDEMIALYEDLIKTITEHKEQKKEPFYLQHAITFHNSINRDKRCILAYLNERLNRIKEYRWSSGQSLLPDQLKERLSQNEIQFFSEYDKILTEYNSKVGLDLTIDPQPPKELYIEVRVIKELGEVVLNSGCTVNLNLNTTHFLKRSDITNLVKNGSLEHII", "length": 191 }, "evidence": [ { "id": "F1NW60", "url": "https://omabrowser.org/oma/group/F1NW60/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q9CZ15-1", "protein_name": "DNA replication complex GINS protein PSF1", "gene_name": "Gins1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFCEKAMELVRELHRAPEGQLPAFNEDGLRQVLEEMKALYEQNQSDVNEAKSAGRGDLIPTVKFRHCALLRNRRCTIAYLYDRLLRIRALRWEYGSVLPNSLRFHMSAEETEWFNHYKKSLATYMRSLGGDEGLDITQDVKPPKSLYIEVRCLKDYGEFEVDDGTSVLLKKNSQHFLPRWKCEQLIRQGVLEHVLS", "length": 196 }, "evidence": [ { "id": "F1NW60", "url": "https://omabrowser.org/oma/group/F1NW60/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9W0I7-1", "protein_name": "DNA replication complex GINS protein PSF1", "gene_name": "Psf1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSRQTKMFGEKAFDLLKELERSSQTIPAFDDDGVRQVLEEIKAIFEENVAQASSYNASGDRSLWPLLNFRHAALQRNKRCLLAYLYERCRRIKALRWEFGPIIPGDIKQALCEPEVTFFNNYSKSLAAYMCSAGYNQGLPIDLTNNLRPPKSLYIEVRCMEDYGKFELDDGEVIHLKKNSQHYLPRAQVESLVRQGILHHIA", "length": 202 }, "evidence": [ { "id": "F1NW60", "url": "https://omabrowser.org/oma/group/F1NW60/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1NW60", "url": "https://www.uniprot.org/uniprotkb/F1NW60" } ], "pmid": "" }, { "name": "GINS complex", "id": "GO:0000811", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000811", "evidence": [ { "database": "UniProtKB", "id": "F1NW60", "url": "https://www.uniprot.org/uniprotkb/F1NW60" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "DNA strand elongation involved in mitotic DNA replication", "id": "GO:1902983", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902983", "evidence": [ { "database": "UniProtKB", "id": "F1NW60", "url": "https://www.uniprot.org/uniprotkb/F1NW60" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1NW60-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 195, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1NW60-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1NW60" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1NW60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NW60" }, { "id": "PF24997", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24997" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "DNA replication complex GINS protein PSF1 C-terminal", "eco_id": "ECO_0000259", "start_pos": 143, "end_pos": 194, "start_aa": "Lys", "end_aa": "Leu", "glycosite_overlap": "" }, { "evidence": [ { "id": "F1NW60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NW60" }, { "id": "PF05916", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05916" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "GINS subunit", "eco_id": "ECO_0000259", "start_pos": 49, "end_pos": 127, "start_aa": "Glu", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1NW62-1", "uniprot_ac": "F1NW62", "uniprot_id": "F1NW62_CHICK", "mass": { "chemical_mass": 74045.0, "monoisotopic_mass": 74045.0 }, "refseq": { "ac": "XP_015149986", "name": "amiloride-sensitive sodium channel subunit gamma", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015149986" }, "gene_names": [ { "name": "SCNN1G", "type": "recommended", "evidence": [ { "id": "F1NW62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NW62" } ] }, { "name": "SCNN1G", "type": "synonym", "evidence": [ { "id": "XP_015149986", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015149986" } ] } ], "protein_names": [ { "name": "Sodium channel epithelial 1 subunit gamma", "type": "synonym", "evidence": [ { "id": "F1NW62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NW62/entry#names_and_taxonomy" } ] }, { "name": "amiloride-sensitive sodium channel subunit gamma", "type": "synonym", "evidence": [ { "id": "XP_015149986", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015149986" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052545.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015149986", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015149986" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NW62", "url": "https://www.uniprot.org/uniprotkb/F1NW62" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SCNN1G", "url": "https://www.uniprot.org/uniprotkb/F1NW62", "locus": { "chromosome": "14", "start_pos": 6987419, "end_pos": 6997902, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010017296", "url": "https://www.ensembl.org/id/ENSGALG00010017296" } ] } } ], "crossref": [ { "id": "F1NW62", "url": "https://alphafold.ebi.ac.uk/entry/F1NW62", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000006270", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000006270", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "416579", "url": "https://www.ncbi.nlm.nih.gov/gene/416579", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001873", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001873", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004724", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004724", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020903", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020903", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:416579", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416579", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "KKYPNWM", "url": "https://omabrowser.org/oma/group/KKYPNWM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1NW62", "url": "https://www.orthodb.org/?gene=F1NW62", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11690", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11690", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11690:SF19", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11690:SF19", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00858", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00858", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-2672351", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2672351", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9730628", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9730628", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_015149986", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015149986", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "34963", "url": "https://www.rhea-db.org/rhea/34963", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "F1NW62", "url": "https://www.uniprot.org/uniprotkb/F1NW62", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NW62-1", "url": "https://www.uniprot.org/uniprotkb/F1NW62-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAPGKITARIKKTLPVRGPQAPTLRELMRWYCLNTNTHGCRRIVVSRGRLRRFIWILLTLSAVGLILWQCAELLLNYYSASVSVTVQFQKLPFPAVTICNINPYKYSSMKDYLSELDKETKKALETFYGFSEGKTKVRRAAGDWNGTESLFFRHVPLLRFENSFRAATDLRSGRKRKVEGSVFHKDSSIVNSGDSNDIIGFQLCDANNSSECALYTFSSGVNAIQEWYKLHYMNIMAQIPLETKEELSYSADDLLLTCFFDGLSCDKRHFTRFHHPLHGNCYTFNSGENGTVLSTSTGGSEYGLQVVLYIDEADYNPFLVTSTGAKIIVHDQDEYPFIEDIGTEIETAAATSIGMHFTRSRKLSKPYSDCTETGADIPVENLYNKSYSLQICLHSCFQKAMVESCGCAQYAQPLPNGAEYCNYKKNPNWMYCYYRLHEKFVKEQLGCQQICKDACSFKEWALTTSIAQWPSTVSEDWMLRVLSWDKGQKINKKLNKTDLANLMVFYKDLNERFISENPANTLVILLSNFGGQLGLWMSCSVVCVIEIIEVFFIDSFSIVMRRQWQKAKKWWNHRKRDETGKPPEVGDAEQQGHDNPACSDEDLPTFNTALRLPLPQEGHPPRTPPPNYSTLRLETAFTEQLPDTLEAGQH", "length": 650, "header": "tr|F1NW62-1|F1NW62_CHICK Isoform 1 of Sodium channel epithelial 1 subunit gamma OS=Gallus gallus OX=9031 GN=SCNN1G PE=3 SV=2 CANONICAL=F1NW62-1" }, "isoforms": [ { "isoform_ac": "F1NW62-1", "url": "https://www.uniprot.org/uniprotkb/F1NW62/entry#F1NW62-1", "sequence": { "sequence": "MAPGKITARIKKTLPVRGPQAPTLRELMRWYCLNTNTHGCRRIVVSRGRLRRFIWILLTLSAVGLILWQCAELLLNYYSASVSVTVQFQKLPFPAVTICNINPYKYSSMKDYLSELDKETKKALETFYGFSEGKTKVRRAAGDWNGTESLFFRHVPLLRFENSFRAATDLRSGRKRKVEGSVFHKDSSIVNSGDSNDIIGFQLCDANNSSECALYTFSSGVNAIQEWYKLHYMNIMAQIPLETKEELSYSADDLLLTCFFDGLSCDKRHFTRFHHPLHGNCYTFNSGENGTVLSTSTGGSEYGLQVVLYIDEADYNPFLVTSTGAKIIVHDQDEYPFIEDIGTEIETAAATSIGMHFTRSRKLSKPYSDCTETGADIPVENLYNKSYSLQICLHSCFQKAMVESCGCAQYAQPLPNGAEYCNYKKNPNWMYCYYRLHEKFVKEQLGCQQICKDACSFKEWALTTSIAQWPSTVSEDWMLRVLSWDKGQKINKKLNKTDLANLMVFYKDLNERFISENPANTLVILLSNFGGQLGLWMSCSVVCVIEIIEVFFIDSFSIVMRRQWQKAKKWWNHRKRDETGKPPEVGDAEQQGHDNPACSDEDLPTFNTALRLPLPQEGHPPRTPPPNYSTLRLETAFTEQLPDTLEAGQH", "length": 650, "header": "tr|F1NW62-1|F1NW62_CHICK Isoform 1 of Sodium channel epithelial 1 subunit gamma OS=Gallus gallus OX=9031 GN=SCNN1G PE=3 SV=2 CANONICAL=F1NW62-1" }, "locus": { "chromosome": "14", "start_pos": 6997564, "end_pos": 6988501, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010041702.1", "url": "https://www.ensembl.org/id/ENSGALT00010041702.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024393.1", "url": "https://www.ensembl.org/id/ENSGALP00010024393.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:416579", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416579", "resource": "KEGG Pathway" }, { "id": "R-GGA-2672351", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2672351", "resource": "Reactome", "description": "Stimuli-sensing channels" }, { "id": "R-GGA-9730628", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9730628", "resource": "Reactome", "description": "Sensory perception of salty taste" } ], "orthologs": [ { "uniprot_canonical_ac": "F1MJW3-1", "protein_name": "Epithelial sodium channel subunit gamma", "gene_name": "SCNN1G", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAPGEKIKAKIKKNLPVTGPQAPNIKELMQWYCLNTNTHGCRRIVVSRGRLRRLLWILFTLTAVALIFWQCALLISSFYTVSVSIKVHFQKLDFPAVTICNINPYKYSAVRHLLADLEQETRAALKTLYGFSEITSRKRREAQSWSSVRKGTDPKFLNLAPLMAFEKGDTGKARDFFTGRKRKVNARIIHKASDVMHIHNSKEVVGFQLCSNDTSDCAVYTFSSGVNAIQEWYKLHYMNIMAQVSQEKKINMSYSADELLVTCFFDGVSCDARNFTLFHHPMYGNCYTFNNRQNETILSTSMGGSEFGLQVILYINEEEYNPFLVSSTGAKVIIHRQDEYPFVEDVGTEIETAMATSIGMHLTESFKLSDPYSQCTEDWSDVQITNIYNATYSLQICLHSCFQAKMVENCGCAQYSQPLPRGADYCNYQQHPNWMYCYYQLHQAFVREELGCQSVCKEACSFKEWTLTTSLAQWPSEVSEKWLLSILTWDQSQQIKKKLNKTDLAKLLIFYKDLNQRSIMENPANSIEQLLSNIGGQLGLWMSCSVVCVIEIIEVFFIDSLSIIARHQWHKAKGWWARRRAPACPEAPRAPQGRDNPSLDIDDDLPTFTSALSLPPAPGSQVPGTPPPRYNTLRLERAFSSQLTDTQTTFPH", "length": 652 }, "evidence": [ { "id": "F1NW62", "url": "https://omabrowser.org/oma/group/F1NW62/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P37091-1", "protein_name": "Epithelial sodium channel subunit gamma", "gene_name": "Scnn1g", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAPGEKIKAKIKKNLPVRGPQAPTIKDLMHWYCMNTNTHGCRRIVVSRGRLRRLLWIAFTLTAVALIIWQCALLVFSFYTVSVSIKVHFQKLDFPAVTICNINPYKYSAVSDLLTDLDSETKQALLSLYGVKESRKRREAGSMPSTLEGTPPRFFKLIPLLVFNENEKGKARDFFTGRKRKISGKIIHKASNVMHVHESKKLVGFQLCSNDTSDCATYTFSSGINAIQEWYKLHYMNIMAQVPLEKKINMSYSAEELLVTCFFDGMSCDARNFTLFHHPMYGNCYTFNNKENATILSTSMGGSEYGLQVILYINEDEYNPFLVSSTGAKVLIHQQNEYPFIEDVGMEIETAMSTSIGMHLTESFKLSEPYSQCTEDGSDVPVTNIYNAAYSLQICLYSCFQTKMVEKCGCAQYSQPLPPAANYCNYQQHPNWMYCYYQLYQAFVREELGCQSVCKQSCSFKEWTLTTSLAQWPSEASEKWLLNVLTWDQSQQINKKLNKTDLAKLLIFYKDLNQRSIMESPANSIEMLLSNFGGQLGLWMSCSVVCVIEIIEVFFIDFFSIIARRQWHKAKDWWARRQTPPSTETPSSRQGQDNPALDTDDDLPTFTSAMRLPPAPGSTVPGTPPPRYNTLRLDRAFSSQLTDTQLTNEL", "length": 650 }, "evidence": [ { "id": "F1NW62", "url": "https://omabrowser.org/oma/group/F1NW62/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P51170-1", "protein_name": "Epithelial sodium channel subunit gamma", "gene_name": "SCNN1G", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAPGEKIKAKIKKNLPVTGPQAPTIKELMRWYCLNTNTHGCRRIVVSRGRLRRLLWIGFTLTAVALILWQCALLVFSFYTVSVSIKVHFRKLDFPAVTICNINPYKYSTVRHLLADLEQETREALKSLYGFPESRKRREAESWNSVSEGKQPRFSHRIPLLIFDQDEKGKARDFFTGRKRKVGGSIIHKASNVMHIESKQVVGFQLCSNDTSDCATYTFSSGINAIQEWYKLHYMNIMAQVPLEKKINMSYSAEELLVTCFFDGVSCDARNFTLFHHPMHGNCYTFNNRENETILSTSMGGSEYGLQVILYINEEEYNPFLVSSTGAKVIIHRQDEYPFVEDVGTEIETAMVTSIGMHLTESFKLSEPYSQCTEDGSDVPIRNIYNAAYSLQICLHSCFQTKMVEKCGCAQYSQPLPPAANYCNYQQHPNWMYCYYQLHRAFVQEELGCQSVCKEACSFKEWTLTTSLAQWPSVVSEKWLLPVLTWDQGRQVNKKLNKTDLAKLLIFYKDLNQRSIMESPANSIEMLLSNFGGQLGLWMSCSVVCVIEIIEVFFIDFFSIIARRQWQKAKEWWAWKQAPPCPEAPRSPQGQDNPALDIDDDLPTFNSALHLPPALGTQVPGTPPPKYNTLRLERAFSNQLTDTQMLDEL", "length": 649 }, "evidence": [ { "id": "F1NW62", "url": "https://omabrowser.org/oma/group/F1NW62/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9WU39-1", "protein_name": "Epithelial sodium channel subunit gamma", "gene_name": "Scnn1g", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAPGEKIKAKIKKNLPVRGPQAPTIKDLMHWYCLNTNTHGCRRIVVSRGRLRRLLWIAFTLTAVALIIWQCALLVFSFYTVSVSIKVHFQKLDFPAVTICNINPYKYSAVSDLLTDLDSETKQALLSLYGVKDVLDSTPRKRREAGSMRSTWEGTPPRFLNLIPLLVFNENEKGKARDFFTGRKRKISGKIIHKASNVMHVHESKKLVGFQLCSNDTSDCATYTFSSGINAIQEWYKLHYMNIMAQVPLEKKINMSYSAEELLVTCFFDGMSCDARNFTLFHHPMYGNCYTFNNRENATILSTSMGGSEYGLQVILYINEDEYNPFLVSSTGAKVLVHQQNEYPFIEDVGTEIETAMSTSIGMHLTESFKLSEPYSQCTEDGSDVPVTNIYNAAYSLQICLYSCFQTKMVEKCGCAQYSQPLPPAANYCNYQQHPNWMYCYYQLYQAFVREELGCQSVCKQSCSFKEWTLTTSLAQWPSEASEKWLLNVLTWDQSQQINKKLNKTDLAKLLIFYKDLNQRSIMESPANSIEMLLSNFGGQLGLWMSCSVVCVIEIIEVFFIDFFSIIARRQWQKAKDWWARRRTPPSTETPSSQQGQDNPALDTDDDLPTFTSAMRLPPAPEAPVPGTPPPRYNTLRLDSAFSSQLTDTQLTNEF", "length": 655 }, "evidence": [ { "id": "F1NW62", "url": "https://omabrowser.org/oma/group/F1NW62/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F1NW62", "url": "https://www.uniprot.org/uniprotkb/F1NW62" } ], "pmid": "" }, { "name": "extracellular exosome", "id": "GO:0070062", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070062", "evidence": [ { "database": "UniProtKB", "id": "F1NW62", "url": "https://www.uniprot.org/uniprotkb/F1NW62" } ], "pmid": "" }, { "name": "external side of plasma membrane", "id": "GO:0009897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009897", "evidence": [ { "database": "UniProtKB", "id": "F1NW62", "url": "https://www.uniprot.org/uniprotkb/F1NW62" } ], "pmid": "" }, { "name": "apical plasma membrane", "id": "GO:0016324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016324", "evidence": [ { "database": "UniProtKB", "id": "F1NW62", "url": "https://www.uniprot.org/uniprotkb/F1NW62" } ], "pmid": "" }, { "name": "sodium channel complex", "id": "GO:0034706", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034706", "evidence": [ { "database": "UniProtKB", "id": "F1NW62", "url": "https://www.uniprot.org/uniprotkb/F1NW62" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "intracellular sodium ion homeostasis", "id": "GO:0006883", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006883", "evidence": [ { "database": "UniProtKB", "id": "F1NW62", "url": "https://www.uniprot.org/uniprotkb/F1NW62" } ], "pmid": "" }, { "name": "sodium ion transmembrane transport", "id": "GO:0035725", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035725", "evidence": [ { "database": "UniProtKB", "id": "F1NW62", "url": "https://www.uniprot.org/uniprotkb/F1NW62" } ], "pmid": "" }, { "name": "multicellular organismal-level water homeostasis", "id": "GO:0050891", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050891", "evidence": [ { "database": "UniProtKB", "id": "F1NW62", "url": "https://www.uniprot.org/uniprotkb/F1NW62" } ], "pmid": "" }, { "name": "cellular response to acidic pH", "id": "GO:0071468", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071468", "evidence": [ { "database": "UniProtKB", "id": "F1NW62", "url": "https://www.uniprot.org/uniprotkb/F1NW62" } ], "pmid": "" }, { "name": "sodium ion import across plasma membrane", "id": "GO:0098719", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098719", "evidence": [ { "database": "UniProtKB", "id": "F1NW62", "url": "https://www.uniprot.org/uniprotkb/F1NW62" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "WW domain binding", "id": "GO:0050699", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050699", "evidence": [ { "database": "UniProtKB", "id": "F1NW62", "url": "https://www.uniprot.org/uniprotkb/F1NW62" } ], "pmid": "" }, { "name": "ligand-gated sodium channel activity", "id": "GO:0015280", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015280", "evidence": [ { "database": "UniProtKB", "id": "F1NW62", "url": "https://www.uniprot.org/uniprotkb/F1NW62" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 145, "end_pos": 147, "annotation": "n_glycosylation_sequon" }, { "start_pos": 207, "end_pos": 209, "annotation": "n_glycosylation_sequon" }, { "start_pos": 208, "end_pos": 210, "annotation": "n_glycosylation_sequon" }, { "start_pos": 289, "end_pos": 291, "annotation": "n_glycosylation_sequon" }, { "start_pos": 384, "end_pos": 386, "annotation": "n_glycosylation_sequon" }, { "start_pos": 495, "end_pos": 497, "annotation": "n_glycosylation_sequon" }, { "start_pos": 627, "end_pos": 629, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "34963", "name": "", "equation": "Na(+)(in) = Na(+)(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "34963", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/34963" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1NW62-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 650, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1NW62-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1NW62" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 145, "end_pos": 147 }, { "start_pos": 207, "end_pos": 209 }, { "start_pos": 208, "end_pos": 210 }, { "start_pos": 289, "end_pos": 291 }, { "start_pos": 384, "end_pos": 386 }, { "start_pos": 495, "end_pos": 497 }, { "start_pos": 627, "end_pos": 629 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": 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"publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1NWF1-1", "uniprot_ac": "F1NWF1", "uniprot_id": "F1NWF1_CHICK", "mass": { "chemical_mass": 22958.0, "monoisotopic_mass": 22958.0 }, "refseq": { "ac": "XP_015135715", "name": "ras-related protein Rab-30", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015135715" }, "gene_names": [ { "name": "RAB30", "type": "recommended", "evidence": [ { "id": "F1NWF1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NWF1" } ] }, { "name": "RAB30", "type": "synonym", "evidence": [ { "id": "XP_015135715", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015135715" } ] } ], "protein_names": [ { "name": "Ras-related protein Rab-30", "type": "recommended", "evidence": [ { "id": "F1NWF1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NWF1/entry#names_and_taxonomy" } ] }, { "name": "3.6.5.2", "type": "synonym", "evidence": [ { "id": "F1NWF1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NWF1/entry#names_and_taxonomy" } ] }, { "name": "ras-related protein Rab-30", "type": "synonym", "evidence": [ { "id": "XP_015135715", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015135715" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015135715", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015135715" } ] }, { "annotation": "The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB30 is required for maintaining the structural integrity of the Golgi apparatus, possibly by mediating interactions with cytoplasmic scaffolding proteins. Facilitates lipid homeostasis during fasting by regulating hepatic protein and lipid trafficking in a PPAR-alpha-dependent manner. Promotes autophagosome biogenesis during bacterial infection such as group A Streptococcus infection.", "evidence": [ { "database": "UniProtKB", "id": "F1NWF1", "url": "https://www.uniprot.org/uniprotkb/F1NWF1#function" }, { "database": "UniProtKB", "id": "ARBA00093384", "url": "https://www.uniprot.org/uniprotkb/ARBA00093384#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NWF1", "url": "https://www.uniprot.org/uniprotkb/F1NWF1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RAB30", "url": "https://www.uniprot.org/uniprotkb/F1NWF1", "locus": { "chromosome": "1", "start_pos": 188959471, "end_pos": 188979749, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010007979", "url": "https://www.ensembl.org/id/ENSGALG00010007979" } ] } } ], "crossref": [ { "id": "F1NWF1", "url": "https://alphafold.ebi.ac.uk/entry/F1NWF1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000017248", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000017248", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd04114", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04114", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "419020", "url": "https://www.ncbi.nlm.nih.gov/gene/419020", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001806", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001806", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005225", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005225", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041820", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041820", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050227", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050227", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:419020", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419020", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "VYDVSCQ", "url": "https://omabrowser.org/oma/group/VYDVSCQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1NWF1", "url": "https://www.orthodb.org/?gene=F1NWF1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47977", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47977", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00071", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00071", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-6811438", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6811438", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_015135715", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015135715", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "19669", "url": "https://www.rhea-db.org/rhea/19669", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "F1NWF1", "url": "https://www.uniprot.org/uniprotkb/F1NWF1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NWF1-1", "url": "https://www.uniprot.org/uniprotkb/F1NWF1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSMEDYDFLFKIVLIGNAGVGKTCLVRRFTQGLFPPGQGATIGVDFMIKTVEINGEKVKLQIWDTAGQERFRSITQSYYRSANALILTYDITCEESFRCLPEWLREIEQYASNKVITVLVGNKIDLADKREVSQQRAAEFSEAQDMYYLETSAKESDNVEKLFLDLACRLISEARQNTLVNNVSSPLPGEGKSISYLTCCNFN", "length": 203, "header": "tr|F1NWF1-1|F1NWF1_CHICK Isoform 1 of Ras-related protein Rab-30 OS=Gallus gallus OX=9031 GN=RAB30 PE=3 SV=2 CANONICAL=F1NWF1-1" }, "isoforms": [ { "isoform_ac": "F1NWF1-1", "url": "https://www.uniprot.org/uniprotkb/F1NWF1/entry#F1NWF1-1", "sequence": { "sequence": "MSMEDYDFLFKIVLIGNAGVGKTCLVRRFTQGLFPPGQGATIGVDFMIKTVEINGEKVKLQIWDTAGQERFRSITQSYYRSANALILTYDITCEESFRCLPEWLREIEQYASNKVITVLVGNKIDLADKREVSQQRAAEFSEAQDMYYLETSAKESDNVEKLFLDLACRLISEARQNTLVNNVSSPLPGEGKSISYLTCCNFN", "length": 203, "header": "tr|F1NWF1-1|F1NWF1_CHICK Isoform 1 of Ras-related protein Rab-30 OS=Gallus gallus OX=9031 GN=RAB30 PE=3 SV=2 CANONICAL=F1NWF1-1" }, "locus": { "chromosome": "1", "start_pos": 188968718, "end_pos": 188960475, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010019006.1", "url": "https://www.ensembl.org/id/ENSGALT00010019006.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010010555.1", "url": "https://www.ensembl.org/id/ENSGALP00010010555.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "gga:419020", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419020", "resource": "KEGG Pathway" }, { "id": "R-GGA-6811438", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6811438", "resource": "Reactome", "description": "Intra-Golgi traffic" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3L7HXE9-1", "protein_name": "Ras-related protein Rab-30", "gene_name": "Rab30", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSMEDYDFLFKIVLIGNAGVGKTCLVRRFTQGLFPPGQGATIGVDFMIKTVEINGEKVKLQIWDTAGQERFRSITQSYYRSANALILTYDITCEESFRCLPEWLREIEQYASNKVITVLVGNKIDLAERREVSQQRAEEFSEAQDMYYLETSAKESDNVEKLFLDLACRLISEARQNTLVNNVSSPLPGEGKSISYLTCCNFN", "length": 203 }, "evidence": [ { "id": "F1NWF1", "url": "https://omabrowser.org/oma/group/F1NWF1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "F2Z5W1-1", "protein_name": "Ras-related protein Rab-30", "gene_name": "RAB30", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSMEDYDFLFKIVLIGNAGVGKTCLVRRFTQGLFPPGQGATIGVDFMIKTVEINGEKVKLQIWDTAGQERFRSITQSYYRSANALILTYDITCEESFRCLPEWLREIEQYASNKVITVLVGNKIDLAERREVSQQRAEEFSEAQDMYYLETSAKESDNVEKLFLDLACRLISEARQNTLVNNVSSPLPGEGKSISYLTCCNFN", "length": 203 }, "evidence": [ { "id": "F1NWF1", "url": "https://omabrowser.org/oma/group/F1NWF1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "O49841-1", "protein_name": "Ras-related protein RABC2a", "gene_name": "RABC2A", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MGSSSGQSGYDLSFKILLIGDSGVGKSSLLVSFISSSVEDLAPTIGVDFKIKQLTVGGKRLKLTIWDTAGQERFRTLTSSYYRGAQGIILVYDVTRRETFTNLVDVWGKEIELYSTNQECVRMLVGNKVDRESERGVSREEGIALAKELNCMFLECSARTRQNVEQCFEELALKIMEVPSLLEEGSSAVKRNILKQKPEHQTNTQSGCCS", "length": 210 }, "evidence": [ { "id": "F1NWF1", "url": "https://omabrowser.org/oma/group/F1NWF1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q15771-1", "protein_name": "Ras-related protein Rab-30", "gene_name": "RAB30", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSMEDYDFLFKIVLIGNAGVGKTCLVRRFTQGLFPPGQGATIGVDFMIKTVEINGEKVKLQIWDTAGQERFRSITQSYYRSANALILTYDITCEESFRCLPEWLREIEQYASNKVITVLVGNKIDLAERREVSQQRAEEFSEAQDMYYLETSAKESDNVEKLFLDLACRLISEARQNTLVNNVSSPLPGEGKSISYLTCCNFN", "length": 203 }, "evidence": [ { "id": "F1NWF1", "url": "https://omabrowser.org/oma/group/F1NWF1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q17QB7-1", "protein_name": "Ras-related protein Rab-30", "gene_name": "RAB30", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSMEDYDFLFKIVLIGNAGVGKTCLVRRFTQGLFPPGQGATIGVDFMIKTVEINGEKVKLQIWDTAGQERFRSITQSYYRSANALILTYDITCEESFRCLPEWLREIEQYASNKVITVLVGNKIDLAERREVSQQRAEEFSEAQDMYYLETSAKESDNVEKLFLDLACRLISEARQNTLVNNVSSPLPGEGKSISYLTCCNFN", "length": 203 }, "evidence": [ { "id": "F1NWF1", "url": "https://omabrowser.org/oma/group/F1NWF1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q923S9-1", "protein_name": "Ras-related protein Rab-30", "gene_name": "Rab30", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSMEDYDFLFKIVLIGNAGVGKTCLVRRFTQGLFPPGQGATIGVDFMIKTVEINGEKVKLQIWDTAGQERFRSITQSYYRSANALILTYDITCEESFRCLPEWLREIEQYASNKVITVLVGNKIDLAERREVSQQRAEEFSEAQDMYYLETSAKESDNVEKLFLDLACRLISEARQNTLVNNVSSPLPGEGKSISYLTCCNFN", "length": 203 }, "evidence": [ { "id": "F1NWF1", "url": "https://omabrowser.org/oma/group/F1NWF1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VM50-1", "protein_name": "Ras-related protein Rab-30", "gene_name": "Rab30", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MEDYKFLFKIVLVGNAGVGKTCLVRRFTQGLFPPGQGATIGVDFMIKTVEVEGEKIKLQIWDTAGQERFRSITQSYYRSAHALILVYDISCQPTFDCLPDWLREIQEYANSKVLKILVGNKTDRDDREIPTQIGEEFAKQHDMYFLETSAKEAENVERLFYEIAAELIGQARSKDGSSSAAAAAAQRQSEGSSIGLGSFSAKAAQSNCCGGLASGGSNSSQGG", "length": 223 }, "evidence": [ { "id": "F1NWF1", "url": "https://omabrowser.org/oma/group/F1NWF1/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 7, "go_terms": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "F1NWF1", "url": "https://www.uniprot.org/uniprotkb/F1NWF1" } ], "pmid": "" }, { "name": "autophagosome membrane", "id": "GO:0000421", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000421", "evidence": [ { "database": "UniProtKB", "id": "F1NWF1", "url": "https://www.uniprot.org/uniprotkb/F1NWF1" } ], "pmid": "" }, { "name": "cytoplasmic vesicle", "id": "GO:0031410", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031410", "evidence": [ { "database": "UniProtKB", "id": "F1NWF1", "url": "https://www.uniprot.org/uniprotkb/F1NWF1" } ], "pmid": "" }, { "name": "trans-Golgi network", "id": "GO:0005802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005802", "evidence": [ { "database": "UniProtKB", "id": "F1NWF1", "url": "https://www.uniprot.org/uniprotkb/F1NWF1" } ], "pmid": "" }, { "name": "cis-Golgi network membrane", "id": "GO:0033106", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033106", "evidence": [ { "database": "UniProtKB", "id": "F1NWF1", "url": "https://www.uniprot.org/uniprotkb/F1NWF1" } ], "pmid": "" }, { "name": "Golgi cisterna", "id": "GO:0031985", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031985", "evidence": [ { "database": "UniProtKB", "id": "F1NWF1", "url": "https://www.uniprot.org/uniprotkb/F1NWF1" } ], "pmid": "" }, { "name": "autolysosome membrane", "id": "GO:0120281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120281", "evidence": [ { "database": "UniProtKB", "id": "F1NWF1", "url": "https://www.uniprot.org/uniprotkb/F1NWF1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "GTPase activity", "id": "GO:0003924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003924", "evidence": [ { "database": "UniProtKB", "id": "F1NWF1", "url": "https://www.uniprot.org/uniprotkb/F1NWF1" } ], "pmid": "" }, { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "F1NWF1", "url": "https://www.uniprot.org/uniprotkb/F1NWF1" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "F1NWF1", "url": "https://www.uniprot.org/uniprotkb/F1NWF1" } ], "pmid": "" }, { "name": "G protein activity", "id": "GO:0003925", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003925", "evidence": [ { "database": "UniProtKB", "id": "F1NWF1", "url": "https://www.uniprot.org/uniprotkb/F1NWF1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "lipid homeostasis", "id": "GO:0055088", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055088", "evidence": [ { "database": "UniProtKB", "id": "F1NWF1", "url": "https://www.uniprot.org/uniprotkb/F1NWF1" } ], "pmid": "" }, { "name": "vesicle-mediated transport", "id": "GO:0016192", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016192", "evidence": [ { "database": "UniProtKB", "id": "F1NWF1", "url": "https://www.uniprot.org/uniprotkb/F1NWF1" } ], "pmid": "" }, { "name": "Golgi organization", "id": "GO:0007030", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007030", "evidence": [ { "database": "UniProtKB", "id": "F1NWF1", "url": "https://www.uniprot.org/uniprotkb/F1NWF1" } ], "pmid": "" }, { "name": "Rab protein signal transduction", "id": "GO:0032482", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032482", "evidence": [ { "database": "UniProtKB", "id": "F1NWF1", "url": "https://www.uniprot.org/uniprotkb/F1NWF1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 182, "end_pos": 184, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "19669", "name": "", "equation": "GTP + H2O = GDP + phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YVX9-1", "F1NSA8-1", "R4GJA4-1", "A0A1L1RKZ0-1", "E1BUS1-1", "Q5ZHW4-1", "Q90694-1", "P08070-1", "P09642-1", "P09643-1", "P09644-1", "P09645-1", "Q5F352-1", "Q5ZMS3-1", "Q90705-1", "Q90835-1", "Q90965-1", "Q98932-1", "A0A3Q2UHM4-1", "Q5ZHX1-1", "A0A1D5PT95-1", "E1BQI2-1", "F1NPF0-1", "A0A8V0XVU5-1", "A0A8V0XBX5-1", "A0A8V0Z564-1", "A0A8V0Y9R6-1", "A0A1D5PM27-1", "A0A8V0Z8U4-1", "A0A8V0ZJW2-1", "A0A8V1ABB1-1", "A0A8V0YDX6-1", "E1BWN3-1", "Q5F499-1", "Q5ZKU5-1", "P02552-1", "P08642-1", "P26990-1", "P42558-1", "Q5F470-1", "Q5ZIT5-1", "Q5ZJN2-1", "P50146-1", "A0A8V0ZNW3-1", "A0A8V0YIM0-1", "A0A8V0ZRZ2-1", "A0A8V1A9Z8-1", "Q1KME6-1", "Q5ZLG1-1", "P84172-1", "A0A8V1ACG4-1", "A0A8V0YTL7-1", "A0A3Q2UG55-1", "A0A8V1AIF5-1", "Q5ZHV1-1", "A0A8V0Z5P2-1", "A0A8V0Y4A4-1", "A0A8V0YA62-1", "A0A8V0YVM3-1", "A0A1D5P1F5-1", "A0A8V1ADZ7-1", "F1NWF1-1", "A0A8V1AP30-1", "A0A8V0XDD5-1", "A0A8V0XMC5-1", "A0A8V0YWW1-1", "A0A8V0ZR14-1", "A0A8V0Y2H3-1", "Q5ZJD3-1", "Q5ZM73-1", "Q5ZM83-1", "A0A8V0YTY9-1", "A0A8V0ZXW3-1", "A0A8V1AHB3-1", "A0A8V0YDI7-1", "A0A1D5NV13-1", "A0A8V0XGK7-1", "A0A8V0YHK2-1", "A0A8V0XC33-1", "A0A8V0XKC3-1", "F1P278-1", "A0A8V0ZG00-1", "A0A8V1AGP3-1", "A0A8V1AN75-1", "A0A8V0Z416-1", "A0A8V1A0V4-1", "A0A8V1A8Q7-1", "A0A8V1ABD3-1", "A0A8V1API8-1", "A0A8V0YIU8-1", "A0A8V0X962-1", "A0A8V1AKH3-1", "P79784-1", "A0A1D5P533-1", "A0A8V1A8I5-1", "A0A8V1AE09-1", "Q9PSX7-1", "Q5ZKR4-1", "A0A8V0YGN8-1", "A0A8V0XNL0-1", "A0A8V0Y3H2-1" ], "evidence": [ { "id": "19669", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/19669" } ] }, { "id": "R-GGA-8849748", "name": "The COG complex binds RABs at the Golgi membrane", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "Golgi membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1NWF1-1", "A0A8V1ABD3-1" ], "evidence": [ { "id": "R-GGA-8849748", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8849748" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A1D5NV13", "gene_name": "RIT2", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5NV13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NV13" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A1D5NV13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NV13" } ] } ] }, { "uniprot_ac": "A0A1D5P1F5", "gene_name": "RAB40C", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5P1F5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P1F5" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A1D5P1F5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P1F5" } ] } ] }, { "uniprot_ac": "A0A1D5P533", "gene_name": "RASEF", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5P533", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P533" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A1D5P533", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P533" } ] } ] }, { "uniprot_ac": "A0A1D5PM27", "gene_name": "OPA1", "activity": [ { "ec_number": "3.6.5.5", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5PM27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PM27" } ] }, { "ec_number": "3.6.5.5", "activity": "", "evidence": [ { "id": "A0A1D5PM27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PM27" } ] } ] }, { "uniprot_ac": "A0A1D5PT95", "gene_name": "KRAS", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5PT95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PT95" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A1D5PT95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PT95" } ] } ] }, { "uniprot_ac": "A0A1L1RKZ0", "gene_name": "RASL11AL", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A1L1RKZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RKZ0" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A1L1RKZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RKZ0" } ] } ] }, { "uniprot_ac": "A0A3Q2UG55", "gene_name": "RAB9B", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q2UG55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UG55" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A3Q2UG55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UG55" } ] } ] }, { "uniprot_ac": "A0A3Q2UHM4", "gene_name": "DNM1L", "activity": [ { "ec_number": "3.6.5.5", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q2UHM4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UHM4" } ] }, { "ec_number": "3.6.5.5", "activity": "", "evidence": [ { "id": "A0A3Q2UHM4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UHM4" } ] } ] }, { "uniprot_ac": "A0A8V0X962", "gene_name": "RAB31", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0X962", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X962" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V0X962", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X962" } ] } ] }, { "uniprot_ac": "A0A8V0XBX5", "gene_name": "RAP2B", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XBX5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XBX5" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V0XBX5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XBX5" } ] } ] }, { "uniprot_ac": "A0A8V0XC33", "gene_name": "RAB23", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XC33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XC33" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V0XC33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XC33" } ] } ] }, { "uniprot_ac": "A0A8V0XDD5", "gene_name": "RAB12", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XDD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XDD5" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V0XDD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XDD5" } ] } ] }, { "uniprot_ac": "A0A8V0XGK7", "gene_name": "RAB6A", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XGK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XGK7" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V0XGK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XGK7" } ] } ] }, { "uniprot_ac": "A0A8V0XKC3", "gene_name": "RAB18", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XKC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XKC3" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V0XKC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XKC3" } ] } ] }, { "uniprot_ac": "A0A8V0XMC5", "gene_name": "RAB10L", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XMC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMC5" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V0XMC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMC5" } ] } ] }, { "uniprot_ac": "A0A8V0XNL0", "gene_name": "RABL2A", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XNL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNL0" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V0XNL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNL0" } ] } ] }, { "uniprot_ac": "A0A8V0XVU5", "gene_name": "RASL11A", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XVU5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XVU5" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V0XVU5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XVU5" } ] } ] }, { "uniprot_ac": "A0A8V0Y2H3", "gene_name": "RAB10", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0Y2H3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2H3" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V0Y2H3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2H3" } ] } ] }, { "uniprot_ac": "A0A8V0Y3H2", "gene_name": "GPN1", "activity": [ { "ec_number": "3.6.5.-", "activity": "", "evidence": [ { "id": "A0A8V0Y3H2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y3H2" } ] } ] }, { "uniprot_ac": "A0A8V0Y4A4", "gene_name": "RAB24", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0Y4A4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y4A4" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V0Y4A4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y4A4" } ] } ] }, { "uniprot_ac": "A0A8V0Y9R6", "gene_name": "RAP1B", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0Y9R6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9R6" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V0Y9R6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9R6" } ] } ] }, { "uniprot_ac": "A0A8V0YA62", "gene_name": "RAB28", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YA62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YA62" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V0YA62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YA62" } ] } ] }, { "uniprot_ac": "A0A8V0YDI7", "gene_name": "RAB17", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YDI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDI7" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V0YDI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDI7" } ] } ] }, { "uniprot_ac": "A0A8V0YDX6", "gene_name": "", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YDX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDX6" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V0YDX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDX6" } ] } ] }, { "uniprot_ac": "A0A8V0YGN8", "gene_name": "RAB21", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YGN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGN8" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V0YGN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGN8" } ] } ] }, { "uniprot_ac": "A0A8V0YHK2", "gene_name": "RAC2", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YHK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHK2" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V0YHK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHK2" } ] } ] }, { "uniprot_ac": "A0A8V0YIM0", "gene_name": "SAR1B", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YIM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIM0" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V0YIM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIM0" } ] } ] }, { "uniprot_ac": "A0A8V0YIU8", "gene_name": 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transmembrane neuronal protein 2 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004944826" }, "gene_names": [ { "name": "LRRTM2", "type": "recommended", "evidence": [ { "id": "F1NWG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NWG8" } ] }, { "name": "LRRTM2", "type": "synonym", "evidence": [ { "id": "XP_004944826", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004944826" } ] } ], "protein_names": [ { "name": "Leucine rich repeat transmembrane neuronal 2", "type": "synonym", "evidence": [ { "id": "F1NWG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NWG8/entry#names_and_taxonomy" } ] }, { "name": "leucine-rich repeat transmembrane neuronal protein 2 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_004944826", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004944826" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052544.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004944826", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004944826" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NWG8", "url": "https://www.uniprot.org/uniprotkb/F1NWG8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LRRTM2", "url": "https://www.uniprot.org/uniprotkb/F1NWG8", "locus": { "chromosome": "13", "start_pos": 2284704, "end_pos": 2280914, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010008396", "url": "https://www.ensembl.org/id/ENSGALG00010008396" } ] } } ], "crossref": [ { "id": "F1NWG8", "url": "https://alphafold.ebi.ac.uk/entry/F1NWG8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000002455", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000002455", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "101747697", "url": "https://www.ncbi.nlm.nih.gov/gene/101747697", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001611", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001611", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003591", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003591", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050467", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050467", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:101747697", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:101747697", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WPLGARM", "url": "https://omabrowser.org/oma/group/WPLGARM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1NWG8", "url": "https://www.orthodb.org/?gene=F1NWG8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45842", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45842", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45842:SF22", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45842:SF22", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13855", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13855", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_004944826", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004944826", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1NWG8", "url": "https://www.uniprot.org/uniprotkb/F1NWG8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NWG8-1", "url": "https://www.uniprot.org/uniprotkb/F1NWG8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGLHFKWPLGARMLAALYAMSMVLKMLPALGMACPPKCRCEKLLFYCDSQGFHSVPNTTEKGSLGLSLRHNFITELERDQFASFSQLTWLHLDHNQIATVREDSFQGLYKLKELVLSSNKIFHLPNTTFSQLLNLQNLDLSFNQLSSLHPELLYGLRKLQTLHLRSNSLRTIPVRLFWDCRSLEFLDLSTNRLRSLARNGFAGLIKLRELHLEHNQLTKINFAHFLRLSSLHTLFLQWNKISNLTCGMEWTWGTLEKLDLTGNDIKAIDLTVFETMPNLKTLLLDNNKLSTLDSKILRSLPSLSTVGLSGNLWECSARICALAAWLGAFRGRWEHPILCHGPDHAQGEDILDAVHGFQLCWNASTAAPSAAPTDAPTTEYTKGISSSHFHMGDKEIPTTAGMVVTTEEPFPEPNNAIFTQRVITGTMALLFSFFFIIFIVFISRKCCPPTLRRIRQCSMIQNHRQLRSQTRLHMANMSDQGPYNEYEPTHEGPFIIINGYGQCKCQQLPYKECEV", "length": 515, "header": "tr|F1NWG8-1|F1NWG8_CHICK Isoform 1 of Leucine rich repeat transmembrane neuronal 2 OS=Gallus gallus OX=9031 GN=LRRTM2 PE=3 SV=3 CANONICAL=F1NWG8-1" }, "isoforms": [ { "isoform_ac": "F1NWG8-1", "url": "https://www.uniprot.org/uniprotkb/F1NWG8/entry#F1NWG8-1", "sequence": { "sequence": "MGLHFKWPLGARMLAALYAMSMVLKMLPALGMACPPKCRCEKLLFYCDSQGFHSVPNTTEKGSLGLSLRHNFITELERDQFASFSQLTWLHLDHNQIATVREDSFQGLYKLKELVLSSNKIFHLPNTTFSQLLNLQNLDLSFNQLSSLHPELLYGLRKLQTLHLRSNSLRTIPVRLFWDCRSLEFLDLSTNRLRSLARNGFAGLIKLRELHLEHNQLTKINFAHFLRLSSLHTLFLQWNKISNLTCGMEWTWGTLEKLDLTGNDIKAIDLTVFETMPNLKTLLLDNNKLSTLDSKILRSLPSLSTVGLSGNLWECSARICALAAWLGAFRGRWEHPILCHGPDHAQGEDILDAVHGFQLCWNASTAAPSAAPTDAPTTEYTKGISSSHFHMGDKEIPTTAGMVVTTEEPFPEPNNAIFTQRVITGTMALLFSFFFIIFIVFISRKCCPPTLRRIRQCSMIQNHRQLRSQTRLHMANMSDQGPYNEYEPTHEGPFIIINGYGQCKCQQLPYKECEV", "length": 515, "header": "tr|F1NWG8-1|F1NWG8_CHICK Isoform 1 of Leucine rich repeat transmembrane neuronal 2 OS=Gallus gallus OX=9031 GN=LRRTM2 PE=3 SV=3 CANONICAL=F1NWG8-1" }, "locus": { "chromosome": "13", "start_pos": 2282811, "end_pos": 2280936, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010020085.1", "url": "https://www.ensembl.org/id/ENSGALT00010020085.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010011633.1", "url": "https://www.ensembl.org/id/ENSGALP00010011633.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 373, "start_aa": "Thr", "end_pos": 373, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr373", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:101747697", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:101747697", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287AD04-1", "protein_name": "Leucine rich repeat transmembrane neuronal 2", "gene_name": "LRRTM2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGLHFKWPLGAPMLAAIYAMSMVLKMLPALGMACPPKCRCEKLLFYCDSQGFHSVPNTTDKGSLGLSLRHNHITELERDQFASFSQLTWLHLDHNQISTVKEDAFQGLYKLKELILSSNKIFYLPNTTFTQLINLHNLDLSFNQLSSLHPELFYGLRKLQTLHLRSNSLRTIPVRLFWDCRSLEFLDLSTNRLRSLARNGFAGLIKLRELHLEHNQLTKINFAHFLRLSSLHTLFLQWNKISNLTCGMEWTWGTLEKLDLTGNEIKAIDSTVFETMPNLKILLMDNNKLNSLDAKLFNSLTSLTTVGLSGNLWECSPRICALASWLGSFQGRWEHSILCHSPDHTQGEDILDAVHGFQLCWNLSTTVTAMATTYKDPTTEYTKRISSSSYHVGDKEIPTTAGIAVTTEEHFPEPDNAIFTQRVITGTMALLFSFFFIIFIVFISRKCCPPTLRRIRQCSMIQNHRQLRSQTRLHMSNMSDQGPYSEYEPTHEGPFIIINGYGQCKCQQLPYKECEV", "length": 516 }, "evidence": [ { "id": "F1NWG8", "url": "https://omabrowser.org/oma/group/F1NWG8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "D4A7P2-1", "protein_name": "Leucine-rich repeat transmembrane neuronal protein 2", "gene_name": "Lrrtm2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGLHFKWPLGAPMLAAIYAMSVVLKMLPALGMACPPKCRCEKLLFYCDSQGFHSVPNATDKGSLGLSLRHNHITALERDQFASFSQLTWLHLDHNQISTVKEDAFQGLYKLKELILSSNKIFYLPNTTFTQLINLQNLDLSFNQLSSLHPELFYGLRKLQTLHLRSNSLRTIPVRLFWDCRSLEFLDLSTNRLRSLARNGFAGLIKLRELHLEHNQLTKINFAHFLRLSSLHTLFLQWNKISNLTCGMEWTWSTLEKLDLTGNEIKAIDLTVFETMPNLKILLMDNNKLNSLDSKILSSLRSLTTVGLSGNLWECSPRVCALASWLGSFQGRWEHSILCHSPDHTQGEDILDAVHGFQLCWNLSTTVTAMATTYRDPTTEYTKISSSSYHVGDKEIPTTAGIAVTTEEHFPEPDNAIFTQRVITGTMALLFSFFFIIFIVFISRKCCPPTLRRIRQCSMIQNHRQLRSQTRLHMSNMSDQGPYSEYEPTHEGPFIIINGYGQCKCQQLPYKECEV", "length": 515 }, "evidence": [ { "id": "F1NWG8", "url": "https://omabrowser.org/oma/group/F1NWG8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1R4D3-1", "protein_name": "Leucine-rich repeat transmembrane neuronal protein 2 precursor", "gene_name": "lrrtm2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MGFHSRWPLVGQAPAALCVISMLLCLPPVSCTTCPQKCRCEDLQFYCDTQGLLAPPDGVDKGALGLSLRHNSISELSSDQFFGFTQLTWLHLDHNQITTVHEDAFQGLYKLKDLNLSSNRITKLPNTTFIHLINLQILDLSFNQMTALEPELFHGLRKLQILHLRSNSLRTTPVRAFWDCRSLEYLGLSNNRLRSLARNGFAGLIKLRELHLEHNHLTKINLAHFPRLVALQFLYLQWNKINNLTSTMEWKWTTLEKLDLTGNEIRVLIPEVFETLPSLKILLLDNNKLSNLDSQTMDMWKSLNVIGLSSNLWECTKRICNLATWLSTFKGRWEHSILCYSPEYAQGEEILDAVYGFQLCQNFSAPVVLTSTSTEAMLPDITSSLFGNMQTPTQDFYAEDFGSFTIVTTTTTTTQPPRTALATTMTVEGADVTEDYSAMDNTLLTQRVIIGTMALLFSFFLIIFVVYISRKCCPPTLRRIRHCSAIQNRRQMRTQQRQPMADLATQVPYNEYETSHEEGALVIINGYGQCKCQQLPYKECEV", "length": 542 }, "evidence": [ { "id": "F1NWG8", "url": "https://omabrowser.org/oma/group/F1NWG8/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "O43300-1", "protein_name": "Leucine-rich repeat transmembrane neuronal protein 2", "gene_name": "LRRTM2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGLHFKWPLGAPMLAAIYAMSMVLKMLPALGMACPPKCRCEKLLFYCDSQGFHSVPNATDKGSLGLSLRHNHITELERDQFASFSQLTWLHLDHNQISTVKEDAFQGLYKLKELILSSNKIFYLPNTTFTQLINLQNLDLSFNQLSSLHPELFYGLRKLQTLHLRSNSLRTIPVRLFWDCRSLEFLDLSTNRLRSLARNGFAGLIKLRELHLEHNQLTKINFAHFLRLSSLHTLFLQWNKISNLTCGMEWTWGTLEKLDLTGNEIKAIDLTVFETMPNLKILLMDNNKLNSLDSKILNSLRSLTTVGLSGNLWECSARICALASWLGSFQGRWEHSILCHSPDHTQGEDILDAVHGFQLCWNLSTTVTVMATTYRDPTTEYTKRISSSSYHVGDKEIPTTAGIAVTTEEHFPEPDNAIFTQRVITGTMALLFSFFFIIFIVFISRKCCPPTLRRIRQCSMVQNHRQLRSQTRLHMSNMSDQGPYNEYEPTHEGPFIIINGYGQCKCQQLPYKECEV", "length": 516 }, "evidence": [ { "id": "F1NWG8", "url": "https://omabrowser.org/oma/group/F1NWG8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8BGA3-1", "protein_name": "Leucine-rich repeat transmembrane neuronal protein 2", "gene_name": "Lrrtm2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLHFKWPLGAPMLAAIYAMSVVLKMLPALGMACPPKCRCEKLLFYCDSQGFHSVPNATDKGSLGLSLRHNHITALERDQFASFSQLTWLHLDHNQISTVKEDAFQGLYKLKELILSSNKIFYLPNTTFTQLINLQNLDLSFNQLSSLHPELFYGLRKLQTLHLRSNSLRTIPVRLFWDCRSLEFLDLSTNRLRSLARNGFAGLIKLRELHLEHNQLTKINFAHFLRLSSLHTLFLQWNKISNLTCGMDWTWSTLEKLDLTGNEIKAIDLTVFETMPNLKILLMDNNKLNSLDSKILNSLKSLTTVGLSGNLWECSPRVCALASWLGSFQGRWEHSILCHSPDHTQGEDILDAVHGFQLCWNLSTTVTAMATTYRDPTTEYTKISSSSYHVGDKEIPTTAGIAVTTEEHFPEPDNAIFTQRVITGTMALLFSFFFIIFIVFISRKCCPPTLRRIRQCSMIQNHRQLRSQTRLHMSNMSDQGPYNEYEPTHEGPFIIINGYGQCKCQQLPYKECEV", "length": 515 }, "evidence": [ { "id": "F1NWG8", "url": "https://omabrowser.org/oma/group/F1NWG8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "GABA-ergic synapse", "id": "GO:0098982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098982", "evidence": [ { "database": "UniProtKB", "id": "F1NWG8", "url": "https://www.uniprot.org/uniprotkb/F1NWG8" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F1NWG8", "url": "https://www.uniprot.org/uniprotkb/F1NWG8" } ], "pmid": "" }, { "name": "postsynaptic specialization membrane", "id": "GO:0099634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099634", "evidence": [ { "database": "UniProtKB", "id": "F1NWG8", "url": "https://www.uniprot.org/uniprotkb/F1NWG8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "positive regulation of synapse assembly", "id": "GO:0051965", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051965", "evidence": [ { "database": "UniProtKB", "id": "F1NWG8", "url": "https://www.uniprot.org/uniprotkb/F1NWG8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "signaling receptor activity", "id": "GO:0038023", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038023", "evidence": [ { "database": "UniProtKB", "id": "F1NWG8", "url": "https://www.uniprot.org/uniprotkb/F1NWG8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 126, "end_pos": 128, "annotation": "n_glycosylation_sequon" }, { "start_pos": 243, "end_pos": 245, "annotation": "n_glycosylation_sequon" }, { "start_pos": 362, "end_pos": 364, "annotation": "n_glycosylation_sequon" }, { "start_pos": 476, "end_pos": 478, "annotation": "n_glycosylation_sequon" }, { "start_pos": 57, "end_pos": 59, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1NWG8-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 515, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": 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}, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1NWX0-1", "uniprot_ac": "F1NWX0", "uniprot_id": "F1NWX0_CHICK", "mass": { "chemical_mass": 50060.0, "monoisotopic_mass": 50060.0 }, "refseq": { "ac": "XP_422851", "name": "tubulin alpha-3 chain", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_422851" }, "gene_names": [ { "name": "TUBA3E", "type": "recommended", "evidence": [ { "id": "F1NWX0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NWX0" } ] }, { "name": "TUBA3E", "type": "synonym", "evidence": [ { "id": "XP_422851", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_422851" } ] } ], "protein_names": [ { "name": "Tubulin alpha chain", "type": "recommended", "evidence": [ { "id": "F1NWX0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NWX0/entry#names_and_taxonomy" } ] }, { "name": "tubulin alpha-3 chain", "type": "synonym", "evidence": [ { "id": "XP_422851", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_422851" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052540.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_422851", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_422851" } ] }, { "annotation": "Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.", "evidence": [ { "database": "UniProtKB", "id": "F1NWX0", "url": "https://www.uniprot.org/uniprotkb/F1NWX0#function" }, { "database": "UniProtKB", "id": "RU000352", "url": "https://www.uniprot.org/uniprotkb/RU000352#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NWX0", "url": "https://www.uniprot.org/uniprotkb/F1NWX0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TUBA3E", "url": "https://www.uniprot.org/uniprotkb/F1NWX0", "locus": {} } ], "crossref": [ { "id": "F1NWX0", "url": "https://alphafold.ebi.ac.uk/entry/F1NWX0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000006241", "url": 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{ "id": "IPR017975", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017975", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018316", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018316", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023123", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023123", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036525", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036525", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037103", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037103", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:425049", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:425049", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YMASCIL", "url": "https://omabrowser.org/oma/group/YMASCIL/", "database": "OMA", "categories": [ 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"MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGKHVPRAVFVDLEPTVVDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIVDLVLDRIRKLADLCTGLQGFLIFHSFGGGTGSGFASLLMERLSVDYGKKSKLEFAIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLIGQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLVTYAPVISAEKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCMLYRGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDLAALEKDYEEVGIDSVEAEAEEEDEY", "length": 450, "header": "tr|F1NWX0-1|F1NWX0_CHICK Isoform 1 of Tubulin alpha chain OS=Gallus gallus OX=9031 GN=TUBA3E PE=3 SV=3 CANONICAL=F1NWX0-1" }, "isoforms": [ { "isoform_ac": "F1NWX0-1", "url": "https://www.uniprot.org/uniprotkb/F1NWX0/entry#F1NWX0-1", "sequence": { "sequence": 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"https://www.reactome.org/PathwayBrowser/#R-GGA-983189", "resource": "Reactome", "description": "Kinesins" } ], "orthologs": [ { "uniprot_canonical_ac": "F6RP72-1", "protein_name": "Tubulin alpha chain", "gene_name": "LOC100295712", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MPHSLLCFQRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGKHVPRAVFVDLEPTVVDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIVDLVLDRIRKLADLCTGLQGFLIFHSFGGGTGSGFASLLMERLSVDYGKKSKLEFAIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLIGQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCMLYRGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDLAALEKDYEEVGVDSVEAEAEEGEEY", "length": 458 }, "evidence": [ { "id": "F1NWX0", "url": "https://omabrowser.org/oma/group/F1NWX0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P05214-1", "protein_name": "Tubulin alpha-3 chain", "gene_name": "Tuba3a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGKHVPRAVFVDLEPTVVDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIVDLVLDRIRKLADLCTGLQGFLIFHSFGGGTGSGFASLLMERLSVDYGKKSKLEFAIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLIGQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCMLYRGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDLAALEKDYEEVGVDSVEAEAEEGEEY", "length": 450 }, "evidence": [ { "id": "F1NWX0", "url": "https://omabrowser.org/oma/group/F1NWX0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P06603-1", "protein_name": "Tubulin alpha-1 chain", "gene_name": "alphaTub84B", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": 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"MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGKHVPRAVFVDLEPTVVDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIVDLVLDRIRKLADLCTGLQGFLIFHSFGGGTGSGFASLLMERLSVDYGKKSKLEFAIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLIGQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCMLYRGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDLAALEKDYEEVGVDSVEAEAEEGEEY", "length": 450 }, "evidence": [ { "id": "F1NWX0", "url": "https://omabrowser.org/oma/group/F1NWX0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P32255-1", "protein_name": "Tubulin alpha chain", "gene_name": "tubA", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": 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"MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGKHVPRAVFVDLEPTVVDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIVDLVLDRIRKLADLCTGLQGFLIFHSFGGGTGSGFASLLMERLSVDYGKKSKLEFAIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLIGQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCMLYRGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDLAALEKDYEEVGVDSVEAEAEEGEEY", "length": 450 }, "evidence": [ { "id": "F1NWX0", "url": "https://omabrowser.org/oma/group/F1NWX0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "mitotic cell cycle", "id": "GO:0000278", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000278", "evidence": [ { "database": "UniProtKB", "id": "F1NWX0", "url": "https://www.uniprot.org/uniprotkb/F1NWX0" } ], "pmid": "" }, { "name": "microtubule cytoskeleton organization", "id": "GO:0000226", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000226", "evidence": [ { "database": "UniProtKB", "id": "F1NWX0", "url": "https://www.uniprot.org/uniprotkb/F1NWX0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "structural constituent of cytoskeleton", "id": "GO:0005200", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005200", "evidence": [ { "database": "UniProtKB", "id": "F1NWX0", "url": "https://www.uniprot.org/uniprotkb/F1NWX0" } ], "pmid": "" }, { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "F1NWX0", "url": "https://www.uniprot.org/uniprotkb/F1NWX0" } ], "pmid": "" }, { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "F1NWX0", "url": "https://www.uniprot.org/uniprotkb/F1NWX0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1NWX0", "url": "https://www.uniprot.org/uniprotkb/F1NWX0" } ], "pmid": "" }, { "name": "microtubule", "id": "GO:0005874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005874", "evidence": [ { "database": "UniProtKB", "id": "F1NWX0", "url": "https://www.uniprot.org/uniprotkb/F1NWX0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 380, "end_pos": 382, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "19669", "name": "", "equation": "GTP + H2O = GDP + phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YVX9-1", "F1NSA8-1", "R4GJA4-1", "A0A1L1RKZ0-1", "E1BUS1-1", "Q5ZHW4-1", "Q90694-1", "P08070-1", "P09642-1", "P09643-1", "P09644-1", "P09645-1", "Q5F352-1", "Q5ZMS3-1", "Q90705-1", "Q90835-1", "Q90965-1", "Q98932-1", "A0A3Q2UHM4-1", "Q5ZHX1-1", "A0A1D5PT95-1", "E1BQI2-1", "F1NPF0-1", "A0A8V0XVU5-1", "A0A8V0XBX5-1", "A0A8V0Z564-1", "A0A8V0Y9R6-1", "A0A1D5PM27-1", "A0A8V0Z8U4-1", "A0A8V0ZJW2-1", "A0A8V1ABB1-1", "A0A8V0YDX6-1", "E1BWN3-1", "Q5F499-1", "Q5ZKU5-1", "P02552-1", "P08642-1", "P26990-1", "P42558-1", "Q5F470-1", "Q5ZIT5-1", "Q5ZJN2-1", "P50146-1", "A0A8V0ZNW3-1", "A0A8V0YIM0-1", "A0A8V0ZRZ2-1", "A0A8V1A9Z8-1", "Q1KME6-1", "Q5ZLG1-1", "P84172-1", "A0A8V1ACG4-1", "A0A8V0YTL7-1", "A0A3Q2UG55-1", "A0A8V1AIF5-1", "Q5ZHV1-1", "A0A8V0Z5P2-1", "A0A8V0Y4A4-1", "A0A8V0YA62-1", "A0A8V0YVM3-1", "A0A1D5P1F5-1", "A0A8V1ADZ7-1", "F1NWF1-1", "A0A8V1AP30-1", "A0A8V0XDD5-1", "A0A8V0XMC5-1", "A0A8V0YWW1-1", "A0A8V0ZR14-1", "A0A8V0Y2H3-1", "Q5ZJD3-1", "Q5ZM73-1", "Q5ZM83-1", "A0A8V0YTY9-1", "A0A8V0ZXW3-1", "A0A8V1AHB3-1", "A0A8V0YDI7-1", "A0A1D5NV13-1", "A0A8V0XGK7-1", "A0A8V0YHK2-1", "A0A8V0XC33-1", "A0A8V0XKC3-1", "F1P278-1", "A0A8V0ZG00-1", "A0A8V1AGP3-1", "A0A8V1AN75-1", "A0A8V0Z416-1", "A0A8V1A0V4-1", "A0A8V1A8Q7-1", "A0A8V1ABD3-1", "A0A8V1API8-1", "A0A8V0YIU8-1", "A0A8V0X962-1", "A0A8V1AKH3-1", "P79784-1", "A0A1D5P533-1", "A0A8V1A8I5-1", "A0A8V1AE09-1", "Q9PSX7-1", "Q5ZKR4-1", "A0A8V0YGN8-1", "A0A8V0XNL0-1", "A0A8V0Y3H2-1" ], "evidence": [ { "id": "19669", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/19669" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A1D5NV13", "gene_name": "RIT2", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5NV13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NV13" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A1D5NV13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NV13" } ] } ] }, { "uniprot_ac": "A0A1D5P1F5", "gene_name": "RAB40C", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5P1F5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P1F5" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A1D5P1F5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P1F5" } ] } ] }, { "uniprot_ac": "A0A1D5P533", "gene_name": "RASEF", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5P533", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P533" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A1D5P533", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P533" } ] } ] }, { "uniprot_ac": "A0A1D5PM27", "gene_name": "OPA1", "activity": [ { "ec_number": "3.6.5.5", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5PM27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PM27" } ] }, { "ec_number": "3.6.5.5", "activity": "", "evidence": [ { "id": "A0A1D5PM27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PM27" } ] } ] }, { "uniprot_ac": "A0A1D5PT95", "gene_name": "KRAS", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5PT95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PT95" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A1D5PT95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PT95" } ] } ] }, { "uniprot_ac": "A0A1L1RKZ0", "gene_name": "RASL11AL", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A1L1RKZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RKZ0" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A1L1RKZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RKZ0" } ] } ] }, { "uniprot_ac": "A0A3Q2UG55", "gene_name": "RAB9B", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q2UG55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UG55" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A3Q2UG55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UG55" } ] } ] }, { "uniprot_ac": "A0A3Q2UHM4", "gene_name": "DNM1L", "activity": [ { "ec_number": "3.6.5.5", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q2UHM4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UHM4" } ] }, { "ec_number": "3.6.5.5", "activity": "", "evidence": [ { "id": "A0A3Q2UHM4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UHM4" } ] } ] }, { 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H(+).", "evidence": [ { "id": "A0A8V0XC33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XC33" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V0XC33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XC33" } ] } ] }, { "uniprot_ac": "A0A8V0XDD5", "gene_name": "RAB12", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XDD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XDD5" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V0XDD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XDD5" } ] } ] }, { "uniprot_ac": "A0A8V0XGK7", "gene_name": "RAB6A", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XGK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XGK7" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V0XGK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XGK7" } ] } ] }, { "uniprot_ac": "A0A8V0XKC3", "gene_name": "RAB18", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XKC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XKC3" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V0XKC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XKC3" } ] } ] }, { "uniprot_ac": "A0A8V0XMC5", "gene_name": "RAB10L", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XMC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMC5" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V0XMC5", "database": "UniProtKB", "url": 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"total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1NWX7-1", "uniprot_ac": "F1NWX7", "uniprot_id": "F1NWX7_CHICK", "mass": { "chemical_mass": 10015.0, "monoisotopic_mass": 10015.0 }, "refseq": { "ac": "NP_001289088", "name": "protein transport protein Sec61 subunit beta", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001289088" }, "gene_names": [ { "name": "SEC61B", "type": "recommended", "evidence": [ { "id": "F1NWX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NWX7" } ] }, { "name": 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##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000042.1. On Oct 3, 2014 this sequence version replaced XP_419082.3.", "evidence": [ { "database": "RefSeq", "id": "NP_001289088", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001289088" } ] }, { "annotation": "Necessary for protein translocation in the endoplasmic reticulum.", "evidence": [ { "database": "UniProtKB", "id": "F1NWX7", "url": "https://www.uniprot.org/uniprotkb/F1NWX7#function" }, { "database": "UniProtKB", "id": "PIRNR006398", "url": "https://www.uniprot.org/uniprotkb/PIRNR006398#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NWX7", "url": "https://www.uniprot.org/uniprotkb/F1NWX7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SEC61B", "url": "https://www.uniprot.org/uniprotkb/F1NWX7", "locus": { "chromosome": "2", "start_pos": 89308237, "end_pos": 89320107, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010007593", "url": "https://www.ensembl.org/id/ENSGALG00010007593" } ] } } ], "crossref": [ { "id": "F1NWX7", "url": "https://alphafold.ebi.ac.uk/entry/F1NWX7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000013569", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000013569", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "420997", "url": "https://www.ncbi.nlm.nih.gov/gene/420997", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR016482", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016482", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR030671", "url": "https://www.ebi.ac.uk/interpro/entry/IPR030671", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:420997", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420997", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "SSGMWRF", "url": "https://omabrowser.org/oma/group/SSGMWRF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XP40", "url": "https://www.orthodb.org/?gene=A0A8V0XP40", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y175", "url": "https://www.orthodb.org/?gene=A0A8V0Y175", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NWX7", "url": "https://www.orthodb.org/?gene=F1NWX7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13509", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13509", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03911", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03911", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-9609523", "url": 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"database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPGPSPSATNVGTSGRSPSKAVAPRAAGSTVRQRKNASCGTRSAGRATSTGTGGMWRFYTEDSPGLKVGPVPVLVMSLLFIASVFMLHIWGKYTRS", "length": 96, "header": "tr|F1NWX7-1|F1NWX7_CHICK Isoform 1 of Protein transport protein Sec61 subunit beta OS=Gallus gallus OX=9031 GN=SEC61B PE=1 SV=2 CANONICAL=F1NWX7-1" }, "isoforms": [ { "isoform_ac": "A0A8V0XP40-1", "url": "https://www.uniprot.org/uniprotkb/F1NWX7/entry#A0A8V0XP40-1", "sequence": { "sequence": "MPGPSPSATNVGTSGRSPSKAVAPRAAGSTVRQRKNASCGTRSAGRATSTGTGGMWRFYTEDSPGLKVFTYLPVLLLSVWMLSRRLVVC", "length": 89, "header": "tr|A0A8V0XP40-1|A0A8V0XP40_CHICK Computationally mapped isoform of Sec61 translocon beta subunit OS=Gallus gallus OX=9031 GN=SEC61B PE=1 SV=1 CANONICAL=F1NWX7-1" }, "locus": { "chromosome": "2", "start_pos": 89320017, "end_pos": 89308496, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010018085.1", "url": "https://www.ensembl.org/id/ENSGALT00010018085.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010009962.1", "url": "https://www.ensembl.org/id/ENSGALP00010009962.1" } ] } }, { "isoform_ac": "A0A8V0Y175-1", "url": "https://www.uniprot.org/uniprotkb/F1NWX7/entry#A0A8V0Y175-1", "sequence": { "sequence": "FQSGELPALRFFPSLPSLHPFLPNPASLLPPQPGPSPSATNVGTSGRSPSKAVAPRAAGSTVRQRKNASCGTRSAGRATSTGTGGMWRFYTEDSPGLKVGPVPVLVMSLLFIASVFMLHIWGKYTRS", "length": 127, "header": "tr|A0A8V0Y175-1|A0A8V0Y175_CHICK Computationally mapped isoform of Sec61 translocon beta subunit OS=Gallus gallus OX=9031 GN=SEC61B PE=1 SV=1 CANONICAL=F1NWX7-1" }, "locus": { "chromosome": "2", "start_pos": 89319986, "end_pos": 89316081, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010018077.1", "url": "https://www.ensembl.org/id/ENSGALT00010018077.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010009958.1", "url": "https://www.ensembl.org/id/ENSGALP00010009958.1" } ] } }, { "isoform_ac": "F1NWX7-1", "url": "https://www.uniprot.org/uniprotkb/F1NWX7/entry#F1NWX7-1", "sequence": { "sequence": "MPGPSPSATNVGTSGRSPSKAVAPRAAGSTVRQRKNASCGTRSAGRATSTGTGGMWRFYTEDSPGLKVGPVPVLVMSLLFIASVFMLHIWGKYTRS", "length": 96, "header": "tr|F1NWX7-1|F1NWX7_CHICK Isoform 1 of Protein transport protein Sec61 subunit beta OS=Gallus gallus OX=9031 GN=SEC61B PE=1 SV=2 CANONICAL=F1NWX7-1" }, "locus": { "chromosome": "2", "start_pos": 89320017, "end_pos": 89316081, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010018082.1", "url": "https://www.ensembl.org/id/ENSGALT00010018082.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010009960.1", "url": "https://www.ensembl.org/id/ENSGALP00010009960.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:420997", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420997", "resource": "KEGG Pathway" }, { "id": "R-GGA-9609523", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9609523", "resource": "Reactome", "description": "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A4X1SH59-1", "protein_name": "Protein transport protein Sec61 subunit beta", "gene_name": "SEC61B", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MPGPTPSGTNVGSSGRSPSKAVAARAAGSTVRQRKNASCGTRSAGRTTSAGTGGMWRFYTEDSPGLKVGPVPVLVMSLLFIASVFMLHIWGKYTRS", "length": 96 }, "evidence": [ { "id": "F1NWX7", "url": "https://omabrowser.org/oma/group/F1NWX7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3H7H4-1", "protein_name": "Protein transport protein Sec61 subunit beta", "gene_name": "Sec61b", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MPGPTPSGTNVGSSGRSPSKAVAARAAGSTVRQRKNASCGTRSAGRTTSAGTGGMWRFYTEDSPGLKVGPVPVLVMSLLFIASVFMLHIWGKYTRS", "length": 96 }, "evidence": [ { "id": "F1NWX7", "url": "https://omabrowser.org/oma/group/F1NWX7/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P60468-1", "protein_name": "Protein transport protein Sec61 subunit beta", "gene_name": "SEC61B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPGPTPSGTNVGSSGRSPSKAVAARAAGSTVRQRKNASCGTRSAGRTTSAGTGGMWRFYTEDSPGLKVGPVPVLVMSLLFIASVFMLHIWGKYTRS", "length": 96 }, "evidence": [ { "id": "F1NWX7", "url": "https://omabrowser.org/oma/group/F1NWX7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9CQS8-1", "protein_name": "Protein transport protein Sec61 subunit beta", "gene_name": "Sec61b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPGPTPSGTNVGSSGRSPSKAVAARAAGSTVRQRKNASCGTRSAGRTTSAGTGGMWRFYTEDSPGLKVGPVPVLVMSLLFIAAVFMLHIWGKYTRS", "length": 96 }, "evidence": [ { "id": "F1NWX7", "url": "https://omabrowser.org/oma/group/F1NWX7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "intracellular protein transport", "id": "GO:0006886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006886", "evidence": [ { "database": "UniProtKB", "id": "F1NWX7", "url": "https://www.uniprot.org/uniprotkb/F1NWX7" } ], "pmid": "" }, { "name": "post-translational protein targeting to membrane, translocation", "id": "GO:0031204", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031204", "evidence": [ { "database": "UniProtKB", "id": "F1NWX7", "url": "https://www.uniprot.org/uniprotkb/F1NWX7" } ], "pmid": "" }, { "name": "SRP-dependent cotranslational protein targeting to membrane, translocation", "id": "GO:0006616", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006616", "evidence": [ { "database": "UniProtKB", "id": "F1NWX7", "url": "https://www.uniprot.org/uniprotkb/F1NWX7" } ], "pmid": "" }, { "name": "retrograde protein transport, ER to cytosol", "id": "GO:0030970", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030970", "evidence": [ { "database": "UniProtKB", "id": "F1NWX7", "url": "https://www.uniprot.org/uniprotkb/F1NWX7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "Sec61 translocon complex", "id": "GO:0005784", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005784", "evidence": [ { "database": "UniProtKB", "id": "F1NWX7", "url": "https://www.uniprot.org/uniprotkb/F1NWX7" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "F1NWX7", "url": "https://www.uniprot.org/uniprotkb/F1NWX7" } ], "pmid": "" }, { "name": "endoplasmic reticulum quality control compartment", "id": "GO:0044322", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044322", "evidence": [ { "database": "UniProtKB", "id": "F1NWX7", "url": "https://www.uniprot.org/uniprotkb/F1NWX7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "guanyl-nucleotide exchange factor activity", "id": "GO:0005085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005085", "evidence": [ { "database": "UniProtKB", "id": "F1NWX7", "url": "https://www.uniprot.org/uniprotkb/F1NWX7" } ], "pmid": "" }, { "name": "ribosome binding", "id": "GO:0043022", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043022", "evidence": [ { "database": "UniProtKB", "id": "F1NWX7", "url": "https://www.uniprot.org/uniprotkb/F1NWX7" } ], "pmid": "" }, { "name": "epidermal growth factor binding", "id": "GO:0048408", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048408", "evidence": [ { "database": "UniProtKB", "id": "F1NWX7", "url": "https://www.uniprot.org/uniprotkb/F1NWX7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 36, "end_pos": 38, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 36, "end_pos": 38 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1NX24-1", "uniprot_ac": "F1NX24", "uniprot_id": "F1NX24_CHICK", "mass": { "chemical_mass": 85567.0, "monoisotopic_mass": 85567.0 }, "refseq": { "ac": "XP_015142544", "name": "LARGE xylosyl- and glucuronyltransferase 2 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015142544" }, "gene_names": [ { "name": "LARGE2", "type": "recommended", "evidence": [ { "id": "F1NX24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NX24" } ] }, { "name": "GYLTL1B", "type": "synonym", "evidence": [ { "id": "XP_015142544", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015142544" } ] }, { "name": "LARGE2", "type": "synonym", "evidence": [ { "id": "XP_015142544", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015142544" } ] }, { "name": "LARGE", "type": "synonym", "evidence": [ { "id": "XP_015142544", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015142544" } ] } ], "protein_names": [ { "name": "LARGE xylosyl- and glucuronyltransferase 2 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015142544", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015142544" } ] }, { "name": "LARGE xylosyl- and glucuronyltransferase 2", "type": "synonym", "evidence": [ { "id": "F1NX24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NX24/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052536.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015142544", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015142544" } ] }, { "annotation": "Bifunctional glycosyltransferase with both alpha-1,3-xylosyltransferase and beta-1,3-glucuronyltransferase activities involved in the maturation of alpha-dystroglycan (DAG1) by glycosylation leading to DAG1 binding to laminin G-like domain-containing extracellular proteins with high affinity and in a phosphorylated-O-mannosyl trisaccharide dependent manner. Elongates the glucuronyl-beta-1,4-xylose-beta disaccharide primer structure by adding repeating units [-3-Xylose-alpha-1,3-GlcA-beta-1-] to produce a heteropolysaccharide. Supports the maturation of DAG1 more effectively than LARGE1. In addition, can modify both heparan sulfate (HS)- and chondroitin/dermatan sulfate (CS/DS)-proteoglycans (PGs), namely GPC4, with a glycosaminoglycan (GAG)-like polysaccharide composed of xylose and glucuronic acid to confer laminin binding.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZFH4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFH4#function" }, { "database": "UniProtKB", "id": "ARBA00045795", "url": "https://www.uniprot.org/uniprotkb/ARBA00045795#function" }, { "database": "UniProtKB", "id": "A0A8V0ZMK3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMK3#function" }, { "database": "UniProtKB", "id": "A0A8V0ZMV4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMV4#function" }, { "database": "UniProtKB", "id": "A0A8V0ZT99", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT99#function" }, { "database": "UniProtKB", "id": "F1NX24", "url": "https://www.uniprot.org/uniprotkb/F1NX24#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NX24", "url": "https://www.uniprot.org/uniprotkb/F1NX24" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LARGE2", "url": "https://www.uniprot.org/uniprotkb/F1NX24", "locus": { "chromosome": "5", "start_pos": 23432035, "end_pos": 23452094, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021848", "url": "https://www.ensembl.org/id/ENSGALG00010021848" } ] } } ], "crossref": [ { "id": "F1NX24", "url": "https://alphafold.ebi.ac.uk/entry/F1NX24", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000008418", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000008418", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd06431", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06431", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "423200", "url": "https://www.ncbi.nlm.nih.gov/gene/423200", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002495", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002495", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029044", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029044", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051292", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051292", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "LPCIWNV", "url": "https://omabrowser.org/oma/group/LPCIWNV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZFH4", "url": "https://www.orthodb.org/?gene=A0A8V0ZFH4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZMK3", "url": "https://www.orthodb.org/?gene=A0A8V0ZMK3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZMV4", "url": "https://www.orthodb.org/?gene=A0A8V0ZMV4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZT99", "url": "https://www.orthodb.org/?gene=A0A8V0ZT99", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NX24", "url": "https://www.orthodb.org/?gene=F1NX24", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12270", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12270", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12270:SF23", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12270:SF23", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01501", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01501", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13896", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13896", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015142544", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015142544", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "57336", "url": "https://www.rhea-db.org/rhea/57336", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "67924", "url": "https://www.rhea-db.org/rhea/67924", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "68368", "url": "https://www.rhea-db.org/rhea/68368", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0ZFH4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFH4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZFH4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFH4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZMK3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMK3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZMK3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMK3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZMV4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMV4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZMV4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMV4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZT99", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT99", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZT99-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT99-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NX24", "url": "https://www.uniprot.org/uniprotkb/F1NX24", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NX24-1", "url": "https://www.uniprot.org/uniprotkb/F1NX24-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLCSWRVKLKLLLATITLAVLLSWLYLFVGSLEYGRFLLLPPCLGEQPSRDVEREALASQVRRVEEENQQLRMQLGQVQAEGSDGNPQWAASAEDGPPLGGERNNRTACPKQRMVRKCELLHVAIVCAGHNASRDVVTLVKSILFHRKNPLHFHFITDSVAHQILQTLFQSWMVPSIHVSFYNADDLKPEVSWIPNKHYSGIYGLMKLTLTKALPSNLSKVIVLDTDITFATDIAELWAVFGKFSEKQVIGLVENQSDWYLGNLWKNHKPWPALGRGFNTGVILLLLDRLRRLGWEQMWRLTAERELMSMLSTSLADQDIFNAVIKQNPALVYRLPCFWNVQLSDHTRSELCYTEVSDLKVIHWNSPKKLRVKNKHVEFFRNLYLTFLEYDGNLLRRELFGCASLPSPPSDQLQQALEELDEDDPCYDFRRQHLTQHRVHLFFLQYEFLALPNPTDVTLVAQLSMDRLQMLEAICKHWAGPISLALYMSDAEAQQFLRYAQASEVLSARRNVAYHIVYKEGQFYPINLLRNVALANTQTPYVFLTDIDFLPMYGLYDYLRNSIQQLELPHRKAALIVPAFETLHYRLTFPKSKAELLSMLDMGSLYTFRYHVWPKGHAPTDYAKWRTATVPYRVAWQPDFEPYVVVRRDCPKYDQRFVGFGWNKVSHIMELDAQEYELLVLPNAFMIHMPHAPSFDISKFRLSAGYRGCLQTLREEFHQDLSRKYGAAALKYLTAERNL", "length": 739, "header": "tr|F1NX24-1|F1NX24_CHICK Isoform 1 of LARGE xylosyl- and glucuronyltransferase 2 OS=Gallus gallus OX=9031 GN=LARGE2 PE=3 SV=2 CANONICAL=F1NX24-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZFH4-1", "url": "https://www.uniprot.org/uniprotkb/F1NX24/entry#A0A8V0ZFH4-1", "sequence": { "sequence": "MLCSWRVKLKLLLATITLAVLLSWLYLFVGSLEYGRFLLLPPCLGEQPSRDVEREALASQVRRVEEENQQLRMQLGQVQAEGSDGNPQWAASAEDGPPLGGERNNRTACPKQRMDLTVLCRKKPLLHVAIVCAGHNASRDVVTLVKSILFHRKNPLHFHFITDSVAHQILQTLFQSWMVPSIHVSFYNADDLKPEVSWIPNKHYSGIYGLMKLTLTKALPSNLSKVIVLDTDITFQVIGLVENQSDWYLGNLWKNHKPWPALGRGFNTGVILLLLDRLRRLGWEQMWRLTAERELMSMLSTSLADQDIFNAVIKQNPALVYRLPCFWNVQLSDHTRSELCYTEVSDLKVIHWNSPKKLRVKNKHVEFFRNLYLTFLEYDGNLLRRELFGCASLPSPPSDQLQQALEELDEDDPCYDFRRQHLTQHRVHLFFLQYEFLALPNPTDVTLVAQLSMDRLQMLEAICKHWAGPISLALYMSDAEAQQFLRYAQASEVLSARRNVAYHIVYKEGQFYPINLLRNVALANTQTPYVFLTDIDFLPMYGLYDYLRNSIQQLELPHRKAALIVPAFETLHYRLTFPKSKAELLSMLDMGSLYTFRYHVWPKGHAPTDYAKWRTATVPYRVAWQPDFEPYVVVRRDCPKYDQRFVGFGWNKVSHIMELDAQEYELLVLPNAFMIHMPHAPSFDISKFRLSAGYRGCLQTLREEFHQDLSRKYGAAALKYLTAERNL", "length": 727, "header": "tr|A0A8V0ZFH4-1|A0A8V0ZFH4_CHICK Computationally mapped isoform of LARGE xylosyl- and glucuronyltransferase 2 OS=Gallus gallus OX=9031 GN=LARGE2 PE=3 SV=1 CANONICAL=F1NX24-1" }, "locus": { "chromosome": "5", "start_pos": 23437982, "end_pos": 23433296, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053180.1", "url": "https://www.ensembl.org/id/ENSGALT00010053180.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032042.1", "url": "https://www.ensembl.org/id/ENSGALP00010032042.1" } ] } }, { "isoform_ac": "A0A8V0ZMK3-1", "url": "https://www.uniprot.org/uniprotkb/F1NX24/entry#A0A8V0ZMK3-1", "sequence": { "sequence": "MLCSWRVKLKLLLATITLAVLLSWLYLFVGSLEYGRFLLLPPCLGEQPSRDVEREALASQVRRVEEENQQLRMQLGQVQAEGSDGNPQWAASAEDGPPLGGERNNRTACPKQRMVRKCELLHVAIVCAGHNASRDVVTLVKSILFHRKNPLHFHFITDSVAHQILQTLFQSWMVPSIHVSFYNADDLKPEVSWIPNKHYSGIYGLMKLTLTKALPSNLSKVIVLDTDITFATDIAELWAVFGKFSEKQVIGLVENQSDWYLGNLWKNHKPWPALGRGFNTGVILLLLDRLRRLGWEQMWRLTAERELMSMLSTSLADQDIFNAVIKQNPALVYRLPCFWNVQLSDHTRSELCYTEVSDLKVIHWNSPKKLRVKNKHVEFFRNLYLTFLEYDGNLLRRELFGCASLPSPPSDQQALEELDEDDPCYDFRRQHLTQHRVHLFFLQYEFLALPNPTDVTLVAQLSMDRLQMLEAICKHWAGPISLALYMSDAEAQQFLRYAQASEVLSARRNVAYHIVYKEGQFYPINLLRNVALANTQTPYVFLTDIDFLPMYGLYDYLRNSIQQLELPHRKAALIVPAFETLHYRLTFPKSKAELLSMLDMGSLYTFRYHVWPKGHAPTDYAKWRTATVPYRVAWQPDFEPYVVVRRDCPKYDQRFVGFGWNKVSHIMELDAQEYELLVLPNAFMIHMPHAPSFDISKFRLSAGYRGCLQTLREEFHQDLSRKYGAAALKYLTAERNL", "length": 737, "header": "tr|A0A8V0ZMK3-1|A0A8V0ZMK3_CHICK Computationally mapped isoform of LARGE xylosyl- and glucuronyltransferase 2 OS=Gallus gallus OX=9031 GN=LARGE2 PE=3 SV=1 CANONICAL=F1NX24-1" }, "locus": { "chromosome": "5", "start_pos": 23437982, "end_pos": 23433296, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053173.1", "url": "https://www.ensembl.org/id/ENSGALT00010053173.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032036.1", "url": "https://www.ensembl.org/id/ENSGALP00010032036.1" } ] } }, { "isoform_ac": "A0A8V0ZMV4-1", "url": "https://www.uniprot.org/uniprotkb/F1NX24/entry#A0A8V0ZMV4-1", "sequence": { "sequence": "MLCSWRVKLKLLLATITLAVLLSWLYLFVGSLEYGRFLLLPPCLGEQPSRDVEREALASQVRRVEEENQQLRMQLGQVQAEGSDGNPQWAASAEDGPPLGGERNNRTACPKQRMVRKCELLHVAIVCAGHNASRDVVTLVKSILFHRKNPLHFHFITDSVAHQILQTLFQSWMVPSIHVSFYNADDLKPEVSWIPNKHYSGIYGLMKLTLTKALPSNLSKVIVLDTDITFATDIAELWAVFGKFSEKQVIGLVENQSDWYLGNLWKNHKPWPALGRGFNTGVILLLLDRLRRLGWEQMWRLTAERELMSMLSTSLADQDIFNAVIKQNPALVYRLPCFWNVQLSDHTRSELCYTEVSDLKVIHWNSPKKLRVKNKHVEFFRNLYLTFLEYDGNLLRRELFGCASLPSPPSDQALEELDEDDPCYDFRRQHLTQHRVHLFFLQYEFLALPNPTDVTLVAQLSMDRLQMLEAICKHWAGPISLALYMSDAEAQQFLRYAQASEVLSARRNVAYHIVYKEGQFYPINLLRNVALANTQTPYVFLTDIDFLPMYGLYDYLRNSIQQLELPHRKAALIVPAFETLHYRLTFPKSKAELLSMLDMGSLYTFRYHVWPKGHAPTDYAKWRTATVPYRVAWQPDFEPYVVVRRDCPKYDQRFVGFGWNKVSHIMELDAQEYELLVLPNAFMIHMPHAPSFDISKFRLSAGYRGCLQTLREEFHQDLSRKYGAAALKYLTAERNL", "length": 736, "header": "tr|A0A8V0ZMV4-1|A0A8V0ZMV4_CHICK Computationally mapped isoform of LARGE xylosyl- and glucuronyltransferase 2 OS=Gallus gallus OX=9031 GN=LARGE2 PE=3 SV=1 CANONICAL=F1NX24-1" }, "locus": { "chromosome": "5", "start_pos": 23437982, "end_pos": 23433296, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053157.1", "url": "https://www.ensembl.org/id/ENSGALT00010053157.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032025.1", "url": "https://www.ensembl.org/id/ENSGALP00010032025.1" } ] } }, { "isoform_ac": "A0A8V0ZT99-1", "url": "https://www.uniprot.org/uniprotkb/F1NX24/entry#A0A8V0ZT99-1", "sequence": { "sequence": "MLCSWRVKLKLLLATITLAVLLSWLYLFVGSLEYGRFLLLPPCLGEQPSRDVEREALASQVRRVEEENQQLRMQLGQVQAEGSDGNPQWAASAEDGPPLGGERNNRTACPKQRMVRKCELLHVAIVCAGHNASRDVVTLVKSILFHRKNPLHFHFITDSVAHQILQTLFQSWMVPSIHVSFYNADDLKPEVSWIPNKHYSGIYGLMKLTLTKALPSNLSKVIVLDTDITFATDIAELWAVFGKFSEKQVIGLVENQSDWYLGNLWKNHKPWPALGRGFNTGVILLLLDRLRRLGWEQMWRLTAERELMSMLSTSLADQDIFNAVIKQNPALVYRLPCFWNVQLSDHTRSELCYTEVSDLKVIHWNSPKKLRVKNKHVEFFRNLYLTFLEYDGNLLRRELFGCASLPSPPSDQALEELDEDDPCYDFRRQHLTQHRVHLFFLQYEFLALPNPTDVTLVAQLSMDRLQMLEAICKHWAGPISLALYMSDAEAQQFLRYAQASEVLSARRNVAYHIVYKEGQFYPINLLRNVALANTQTPYVFLTDIDFLPMYGLYDYLRNSIQQLELPHRKAALIVPAFETLHYRLTFPKSKAELLSMLDMGSLYTFRYHVWPKGHAPTDYAKWRTATVPYRVAWQPDFEPYVVVRRDCPKYDQRFVGFGWNKVSHIMELDAQEYELLGLLLPQLTS", "length": 685, "header": "tr|A0A8V0ZT99-1|A0A8V0ZT99_CHICK Computationally mapped isoform of LARGE xylosyl- and glucuronyltransferase 2 OS=Gallus gallus OX=9031 GN=LARGE2 PE=3 SV=1 CANONICAL=F1NX24-1" }, "locus": { "chromosome": "5", "start_pos": 23437982, "end_pos": 23433210, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053167.1", "url": "https://www.ensembl.org/id/ENSGALT00010053167.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032033.1", "url": "https://www.ensembl.org/id/ENSGALP00010032033.1" } ] } }, { "isoform_ac": "F1NX24-1", "url": "https://www.uniprot.org/uniprotkb/F1NX24/entry#F1NX24-1", "sequence": { "sequence": "MLCSWRVKLKLLLATITLAVLLSWLYLFVGSLEYGRFLLLPPCLGEQPSRDVEREALASQVRRVEEENQQLRMQLGQVQAEGSDGNPQWAASAEDGPPLGGERNNRTACPKQRMVRKCELLHVAIVCAGHNASRDVVTLVKSILFHRKNPLHFHFITDSVAHQILQTLFQSWMVPSIHVSFYNADDLKPEVSWIPNKHYSGIYGLMKLTLTKALPSNLSKVIVLDTDITFATDIAELWAVFGKFSEKQVIGLVENQSDWYLGNLWKNHKPWPALGRGFNTGVILLLLDRLRRLGWEQMWRLTAERELMSMLSTSLADQDIFNAVIKQNPALVYRLPCFWNVQLSDHTRSELCYTEVSDLKVIHWNSPKKLRVKNKHVEFFRNLYLTFLEYDGNLLRRELFGCASLPSPPSDQLQQALEELDEDDPCYDFRRQHLTQHRVHLFFLQYEFLALPNPTDVTLVAQLSMDRLQMLEAICKHWAGPISLALYMSDAEAQQFLRYAQASEVLSARRNVAYHIVYKEGQFYPINLLRNVALANTQTPYVFLTDIDFLPMYGLYDYLRNSIQQLELPHRKAALIVPAFETLHYRLTFPKSKAELLSMLDMGSLYTFRYHVWPKGHAPTDYAKWRTATVPYRVAWQPDFEPYVVVRRDCPKYDQRFVGFGWNKVSHIMELDAQEYELLVLPNAFMIHMPHAPSFDISKFRLSAGYRGCLQTLREEFHQDLSRKYGAAALKYLTAERNL", "length": 739, "header": "tr|F1NX24-1|F1NX24_CHICK Isoform 1 of LARGE xylosyl- and glucuronyltransferase 2 OS=Gallus gallus OX=9031 GN=LARGE2 PE=3 SV=2 CANONICAL=F1NX24-1" }, "locus": { "chromosome": "5", "start_pos": 23437982, "end_pos": 23433296, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053178.1", "url": "https://www.ensembl.org/id/ENSGALT00010053178.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032041.1", "url": "https://www.ensembl.org/id/ENSGALP00010032041.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A9J7JZU2-1", "protein_name": "LARGE xylosyl- and glucuronyltransferase 2 isoform X1", "gene_name": "Large2", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MLPRGRPRALGAVTLLLLLLLLVGFFLFGRDPEYGLRAAATLDGDLYGSRNRSAASLQPLLPPKCEVGVPPQLLHVAIVCAGYNSSREVITLVKSLLFYRKNPLHLHLVTDAIARNILETLFRTWMVPAVVIRFYDAEELKPLISWIPNKHYSGLYGLMKLVLPSILPLSLARVIVLDTDVTFSSDIAELWALFAHFSDKQVVGLVENQSDWYLGNLWKNHRPWPALGRGFNTGVILLWLDRLRQTGWEQMWKLIAKQELLTLMATSLADQDVFNAVIKEHPELVHPLPCVWNVQLSDHTLAERCYLEAADLKVIHWNSPKKLRVKNKHAEFFRNLHLTFLGYDGKLLRRELFGCPNQLPPGAEQLQQALAQLDEEEPCFEFRQQQLSVHRVHITFLPHQPPPPRPHDVTLVAQLSMDRLQMLEALCRHWPGPMSLALYLTDAEAQQFLHFVETSPVLSARKDVAYHIVYREGPLYPVNQLRNVALAQALTPYVFLSDIDFLPAYSLYDYLRASIEQLELGSQRKAALVVPAFETLHYRLSFPNSKAELLTLLDAGSLYTFRYHEWPQGHAPTDYARWREAKAPYHVQWAADYEPYVVVPRDCPRYDPRFVGFGWNKVAHIIELDAQEYELLVLPEAFSIHLPHAPSLDISRFRSSPTYRHCLQTLKEEFHQDLSRRYGAAALKYLTALQQSQSRA", "length": 696 }, "evidence": [ { "id": "F1NX24", "url": "https://omabrowser.org/oma/group/F1NX24/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "F1SI95-1", "protein_name": "LARGE xylosyl- and glucuronyltransferase 2", "gene_name": "LARGE2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MLPRGRPRALGAAALLLLLLLLLIGFFLFGGDLDYGRLRPLGAVALDRDPPADHGGHNRSDCVPPRPLPPKCELLQVAIVCAGHNSSRDVITLVKSMLFYRKNPLHLHLVTDAVARNILETLFHTWMVPAVRVSFYDADELKPQVSWIPNKHYSGLYGLMKLVLPGALPPDLARVIVLDTDVTFASNIAELWALFAHFSDKQVIGLVENQSDWYLGNLWRNHRPWPALGRGFNTGVILLRLDRLRQAGWEQMWKLIATQELLTLPATSLADQDIFNAVIKEHPWLVQPLPCVWNVQLSDHTLAERCYSEASDLKVIHWNSPKKLRVKNKHVESFRNLHLTFLEYDGNLLRRELFGCPCPPPPGAEQLQRALAQLDEEDACFEFRQQQLTVHRVHITFLPHKPPPPQPYDVTLVAQLSMDRLQMLEALCRHWPGPMSLALYLTDAEAQQFLRFVETSAVLSARQNVAYHVVYREGPLYPINQLRNVALAQALTPYVFLSDIDFLPAYSLYHYLRASIEQLELGTGGRKVALVVPAFETLHYRFSFPSSKAELLALLDAGSLYTFRYHEWPRGHAPTDYARWREAQAPYRVQWAADYEPYVVVPRDCPRYDPRFVGFGWNKVAHIVELDAQEYELLVLPEAFIIHLPHAPSLDISRFRSSPTYRDCLQALKDEFHQDLSRHYGAAALKYLTALQQPRGPT", "length": 698 }, "evidence": [ { "id": "F1NX24", "url": "https://omabrowser.org/oma/group/F1NX24/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q5XPT3-1", "protein_name": "Xylosyl- and glucuronyltransferase LARGE2", "gene_name": "Large2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLPRGRPRAMGAAVLLLLLLLVVGFFLFGRDPDYGLGTTATLDEDPYRSRNLSASSPQLLLPPKCEMLHVAIVCAGYNSSREIITLTKSLLFYRKNPLHLHLITDAVARNILETLFRTWMVPAVVVSFYDAEELKPLVSWIPNKHYSGLYGLMKLVLPSILPPSLARVIVLDTDVTFSSDIVELWALFDHFSDKQVVGLVENQSDWYLGNLWKNHRPWPALGRGFNTGVILLWLDRLQQTGWEQMWKVTAKRELLTLMATSLADQDIFNAVIKEHPHLVHPLPCVWNVQLSDHTRAERCYLEAADLKVIHWNSPKKLRVKNKHAEFFRNLHLTFLGYDGKLLRRELFGCPNQFPPGAEQLQQALTQLDEEEPCFEFRQQQLTVHRVHITFLPHQPPPPQPHDVTLVAQLSMDRLQMLEALCRHWPGPMSLALYLTDEEAQQFLHFVETSPVLSMRKDVAYHVVYRDGPLYPVNQLRNVALAQALTPYVFLSDIDFLPAYSLYDYLRASIEQLELDSRRKTALVVPAFETLHYRFSFPNSKAELLTLLDAGSLHTFRYHEWPQGHSSTDYSRWREAQAPYSVQWSADYEPYVVVPRDCPRYDPRFVGFGWNKVAHIIELDAQEYEFLVLPEAFSIHLPHAPSLDISRFRSSPTYRNCLQALKEEFHQDLSRRYGSAALKYLTALQQARSRA", "length": 690 }, "evidence": [ { "id": "F1NX24", "url": "https://omabrowser.org/oma/group/F1NX24/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q66PG1-1", "protein_name": "Xylosyl- and glucuronyltransferase LARGE2s", "gene_name": "large2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLCPCRGKLKLLVVSLSFVILFTWLYLLVGNSENGRSLLLSACLVESTEARLLERDVLASRVREVEEENRQIRLQLSQSQGLAGQPAEGNYGNQQWVASADTGPEDVENTAEERANHSECSRSPTAEKCELLHVACVCAGHNASRDVVTLVKSILFHRRNPLHFHFITDTVANQILSTLFQSWMVPSVQVSFYDADELKSEVSWIPNKHYSGIYGLMKLTLTKALPSNLSKVIVLDTDITFATDIAELWAIFRKFTEKQVIGLVENQSDWYLGNLWKNHKPWPALGRGFNTGVILLYLERLRRMGWEQMWRLTAERELMSMLSTSLADQDIFNAFIKQNPVLVHQLPCFWNVQLSDHTRSEQCYTEVSDLKVIHWNSPKKLRVKNKHVEFFRNLYLTFLEYDGNLLRRELFGCPSQASSESTVLQQALEELDEDDQCYDFRRERIMLHRVHLYFLQYEYSPTDDGTDITLVAQLSMDRLQMLEAICKHWEGPISLALYMSDAEAQQFLRYAQASEVLKNRKNVGYHIVYKEGQFYPVNLVRNVALRNVNTPYVFLTDVDFLPMYGLYDYLRKSIVQLDMANTKKALVVPAFETLRYRLSFPKSKAELLSMLDMGTLYTFRYHVWTKGHAPTNYAKWRTATTPYKVEWEADFEPYVVVRRDCPEYDQRFVGFGWNKVSHIMELDAQEYDLIVLPNAFMIHMPHAPSFDISKFRSSPSYRYCLTTLKDEFHQDLSRKYGSAALKYLTAQRNI", "length": 750 }, "evidence": [ { "id": "F1NX24", "url": "https://omabrowser.org/oma/group/F1NX24/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q6P7A1-1", "protein_name": "Xylosyl- and glucuronyltransferase LARGE2", "gene_name": "Large2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLPRGRPRALGAALLLLLLLVVGFFLFGRDPEYGLGTTATLDGDPYGSRNRSTSSLQLLLPPKCEMLHVAIVCAGYNSSREIITLMKSVLFYRKNPLHLHLITDAVARNILETLFRTWMVPAVVVSFYDAEELKPLVSWIPNKHYSGLYGLMKLVLPSVLPLSLARVIVLDTDVTFSSDIMELWALFGHFSDKQVVGLVENQSDWYLGNLWKNHRPWPALGRGFNTGVILLWLDRLQQIGWEQMWKLTAKRELLTLTATSLADQDIFNAVIKEHPELVHPLPCVWNVQLSDHTLAERCYLEAADLKVIHWNSPKKLRVKNKHAEFFRDLHLTFLGFDGKLLCRELFGCPNQFPPGVEQLQQALAQLDEEEPCFEFRQQQLTVHRVHITFLSHQPPPPRPHDVTLVAQLSMDRLQMLEALCRHWRGPMSLALYLTDAEAQQFLRFVETSPVLSARKDVAYHVVYRDGPLYPVNQLRNVALAQALTPYVFLSDIDFLPAYSLYDYLRASIEQLALGRRQRKAALVVPAFETLHYRFSFPNSKAELLTLLDAGSLHTFRYHEWPQGHASTDYTRWREAQAPYRVQWSADYEPYVVVPRDCPRYDPRFVGFGWNKVAHIIELDAQEYEFLVLPEAFSIHLPHAPSLDISRFRSSPTYRDCLQALKEEFHQDLSRRYGSAALKYLTALQQSRSRA", "length": 690 }, "evidence": [ { "id": "F1NX24", "url": "https://omabrowser.org/oma/group/F1NX24/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8N3Y3-1", "protein_name": "Xylosyl- and glucuronyltransferase LARGE2", "gene_name": "LARGE2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLPRGRPRALGAAALLLLLLLLGFLLFGGDLGCERREPGGRAGAPGCFPGPLMPRVPPDGRLRRAAALDGDPGAGPGDHNRSDCGPQPPPPPKCELLHVAIVCAGHNSSRDVITLVKSMLFYRKNPLHLHLVTDAVARNILETLFHTWMVPAVRVSFYHADQLKPQVSWIPNKHYSGLYGLMKLVLPSALPAELARVIVLDTDVTFASDISELWALFAHFSDTQAIGLVENQSDWYLGNLWKNHRPWPALGRGFNTGVILLRLDRLRQAGWEQMWRLTARRELLSLPATSLADQDIFNAVIKEHPGLVQRLPCVWNVQLSDHTLAERCYSEASDLKVIHWNSPKKLRVKNKHVEFFRNFYLTFLEYDGNLLRRELFVCPSQPPPGAEQLQQALAQLDEEDPCFEFRQQQLTVHRVHVTFLPHEPPPPRPHDVTLVAQLSMDRLQMLEALCRHWPGPMSLALYLTDAEAQQFLHFVEASPVLAARQDVAYHVVYREGPLYPVNQLRNVALAQALTPYVFLSDIDFLPAYSLYDYLRASIEQLGLGSRRKAALVVPAFETLRYRFSFPHSKVELLALLDAGTLYTFRYHEWPRGHAPTDYARWREAQAPYRVQWAANYEPYVVVPRDCPRYDPRFVGFGWNKVAHIVELDAQEYELLVLPEAFTIHLPHAPSLDISRFRSSPTYRDCLQALKDEFHQDLSRHHGAAALKYLPALQQPQSPARG", "length": 721 }, "evidence": [ { "id": "F1NX24", "url": "https://omabrowser.org/oma/group/F1NX24/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "xylosyltransferase activity", "id": "GO:0042285", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042285", "evidence": [ { "database": "UniProtKB", "id": "F1NX24", "url": "https://www.uniprot.org/uniprotkb/F1NX24" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "F1NX24", "url": "https://www.uniprot.org/uniprotkb/F1NX24" } ], "pmid": "" }, { "name": "glucuronosyltransferase activity", "id": "GO:0015020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015020", "evidence": [ { "database": "UniProtKB", "id": "F1NX24", "url": "https://www.uniprot.org/uniprotkb/F1NX24" } ], "pmid": "" }, { "name": "UDP-glycosyltransferase activity", "id": "GO:0008194", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008194", "evidence": [ { "database": "UniProtKB", "id": "F1NX24", "url": "https://www.uniprot.org/uniprotkb/F1NX24" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "F1NX24", "url": "https://www.uniprot.org/uniprotkb/F1NX24" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "F1NX24", "url": "https://www.uniprot.org/uniprotkb/F1NX24" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "protein O-linked glycosylation via mannose", "id": "GO:0035269", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035269", "evidence": [ { "database": "UniProtKB", "id": "F1NX24", "url": "https://www.uniprot.org/uniprotkb/F1NX24" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 105, "end_pos": 107, "annotation": "n_glycosylation_sequon" }, { "start_pos": 131, "end_pos": 133, "annotation": "n_glycosylation_sequon" }, { "start_pos": 217, "end_pos": 219, "annotation": "n_glycosylation_sequon" }, { "start_pos": 255, "end_pos": 257, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "57336", "name": "", "equation": "3-O-[beta-D-GlcA-(1->3)-beta-D-Xyl-(1->4)-Rib-ol-P-Rib-ol-P-3-beta-D-GalNAc-(1->3)-beta-D-GlcNAc-(1->4)-(O-6-P-alpha-D-Man)]-Thr-[protein] + UDP-alpha-D-xylose = 3-O-[alpha-D-Xyl-(1->3)-beta-D-GlcA-(1->4)-beta-D-Xyl-(1->4)-Rib-ol-P-Rib-ol-P-3-beta-D-GalNAc-(1->3)-beta-D-GlcNAc-(1->4)-(O-6-P-alpha-D-Man)]-Thr-[protein] + UDP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q66PG4-1", "Q66PG3-1" ], "evidence": [ { "id": "57336", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/57336" } ] }, { "id": "67924", "name": "", "equation": "3-O-{(1->[3)-alpha-D-Xyl-(1->3)-beta-D-GlcA-(1->](n)-4)-beta-D-Xyl-(1->4)-Rib-ol-P-Rib-ol-P-3-beta-D-GalNAc-(1->3)-beta-D-GlcNAc-(1->4)-O-6-P-alpha-D-Man}-L-Thr-[protein] + UDP-alpha-D-glucuronate = 3-O-{beta-D-GlcA-(1->[3)-alpha-D-Xyl-(1->3)-beta-D-GlcA-(1->](n)-4)-beta-D-Xyl-(1->4)-Rib-ol-P-Rib-ol-P-3-beta-D-GalNAc-(1->3)-beta-D-GlcNAc-(1->4)-O-6-P-alpha-D-Man}-L-Thr-[protein] + UDP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q66PG4-1", "Q66PG3-1" ], "evidence": [ { "id": "67924", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/67924" } ] }, { "id": "68368", "name": "", "equation": "3-O-{beta-D-GlcA-(1->[3)-alpha-D-Xyl-(1->3)-beta-D-GlcA-(1->](n)-4)-beta-D-Xyl-(1->4)-Rib-ol-P-Rib-ol-P-3-beta-D-GalNAc-(1->3)-beta-D-GlcNAc-(1->4)-O-6-P-alpha-D-Man}-L-Thr-[protein] + UDP-alpha-D-xylose = 3-O-{(1->[3)-alpha-D-Xyl-(1->3)-beta-D-GlcA-(1->](n+1)-4)-beta-D-Xyl-(1->4)-Rib-ol-P-Rib-ol-P-3-beta-D-GalNAc-(1->3)-beta-D-GlcNAc-(1->4)-O-6-P-alpha-D-Man}-L-Thr-[protein] + UDP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q66PG4-1", "Q66PG3-1" ], "evidence": [ { "id": "68368", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/68368" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "Q66PG3", "gene_name": "LARGE1", "activity": [ { "ec_number": "2.4.2.-", "activity": "", "evidence": [ { "id": "Q66PG3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q66PG3" } ] }, { "ec_number": "2.4.1.-", "activity": "", "evidence": [ { "id": "Q66PG3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q66PG3" } ] }, { "ec_number": "2.4.-.-", "activity": "", "evidence": [ { "id": "Q66PG3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q66PG3" } ] } ] }, { "uniprot_ac": "Q66PG4", "gene_name": "LARGE2", "activity": [ { "ec_number": "2.4.2.-", "activity": "", "evidence": [ { "id": "Q66PG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q66PG4" } ] }, { "ec_number": "2.4.1.-", "activity": "", "evidence": [ { "id": "Q66PG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q66PG4" } ] }, { "ec_number": "2.4.-.-", "activity": "", "evidence": [ { "id": "Q66PG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q66PG4" } ] } ] } ], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1NX24-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 739, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1NX24-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1NX24" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 105, "end_pos": 107 }, { "start_pos": 131, "end_pos": 133 }, { "start_pos": 217, "end_pos": 219 }, { "start_pos": 255, "end_pos": 257 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1NX72-1", "uniprot_ac": "F1NX72", "uniprot_id": "F1NX72_CHICK", "mass": { "chemical_mass": 144973.0, "monoisotopic_mass": 144973.0 }, "refseq": { "ac": "XP_416467", "name": "structural maintenance of chromosomes protein 1B", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_416467" }, "gene_names": [ { "name": "SMC1B", "type": "recommended", "evidence": [ { "id": "F1NX72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NX72" } ] }, { "name": "SMC1B", "type": "synonym", "evidence": [ { "id": "XP_416467", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_416467" } ] } ], "protein_names": [ { "name": "Structural maintenance of chromosomes protein", "type": "recommended", "evidence": [ { "id": "F1NX72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NX72/entry#names_and_taxonomy" } ] }, { "name": "structural maintenance of chromosomes protein 1B", "type": "synonym", "evidence": [ { "id": "XP_416467", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_416467" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process On Nov 16, 2006 this sequence version replaced XP_416467.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_416467", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_416467" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NX72", "url": "https://www.uniprot.org/uniprotkb/F1NX72" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SMC1B", "url": "https://www.uniprot.org/uniprotkb/F1NX72", "locus": { "chromosome": "1", "start_pos": 70445666, "end_pos": 70481978, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012104", "url": "https://www.ensembl.org/id/ENSGALG00010012104" } ] } } ], "crossref": [ { "id": "F1NX72", "url": "https://alphafold.ebi.ac.uk/entry/F1NX72", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000014228", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000014228", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd03275", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03275", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "418243", "url": "https://www.ncbi.nlm.nih.gov/gene/418243", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003395", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003395", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR010935", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010935", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024704", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024704", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028468", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028468", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036277", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036277", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:418243", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418243", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HKARCWD", "url": "https://omabrowser.org/oma/group/HKARCWD/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1NX72", "url": "https://www.orthodb.org/?gene=F1NX72", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR18937", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR18937", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR18937:SF147", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR18937:SF147", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02463", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02463", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF06470", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06470", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_416467", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_416467", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1NX72", "url": "https://www.uniprot.org/uniprotkb/F1NX72", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NX72-1", "url": "https://www.uniprot.org/uniprotkb/F1NX72-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASAPTATGLGYLKLLMVKDFKSWRGEQLIGPFMRFNCIIGPNGSGKSNIMDAVSFVLCEKISNLRVKSVRELIHGAHVGKPVSSTASVKIVYCEEDGEEKTFSRVIRDGCSEYIFNDKSITRSAYISELEKIGILVKARNCLIFQGTVESIAMKKPKERTQLFEQISNSWQYAEEYERKKKKMQQAEEDAHFNYNKKKNIAAERKQAKVEKEEAEHYQMLVRELNANRVQLQLFQLYHNERSIESLKESLDEKNMEARIKKDSLSTAEDTFRAKKKVLGVLNRDQQQMEREMKTLQASLIQQKALYIKAKENTSYQIKKVEMSKRSLRDKEKYCDKEKQNIKELEMELHDTEKAWREFEKEAEEEILLRVERVELRERQLERYKELKEIARRKVATLTQQLGKLRWEQKADEERMKLYQRKKKEVKETIVQTVEQIEEYKKRVEKLEEYTKKCTESLEEEKKKEEMLAKEIENSTTRIAEVNEELNKIVGELQNARIDYHEGKRQQMRAEIVESLKRLYPDSVFGRLLDLCHPIHKKYQLAVTKVFSKYMTAIVVATEKTARDCIQFLKQERAEPETFLALDYLEVKPINERLREIKGAKMIVDVVQTPFAPLKRVIQFVSGNGLVCDTVKEARQIAFEGPVRLKTVALDGTLFLKSGVISGGSSDLRVKARCWDDKEINRMKERRDALITELKDLMKIKRKEADLKQLQAQCHGTQTRLKYSQSELDLIKKKHLPNVYMEKSKLESELVNTESQHDMIKEGVVQRKLKIEEFQKQINEAEDAVFQEFCEEIGIENIRVYEQEHVRRQEEIDKRRLEFENQKTRLSVQLEYNREHLQKLTDAVSKLRDTIHKDESEIAGLQKDEEKHLKRVNEIEEEEQHLKDRLSAQKSEIMKTQSEADELRKTLLTLNREAAKLQKEAAAIEASLEDKRLRRHNMLLECKVQDLKIRLLFGSLDDISEVELGTETEDTQTTGIYEREEAIKIDYSSLPKDLKDLESDKEIEAHLNQMQQEIKSKESILMKTAVPNLRAVEKLQIARNKFQESMEAFEASRKEARISKQEFEEVKKRRYELFSQCFEHASIVIDQVYKKLCRNSSAQAFLSPENPEEPYLEGIGFNCVAPGKRFMPMDSLSGGEKTVAALALIFAVHSFRPAPFFILDEIDAALDNTNIDKVSIFIREQAHKQFQMVVISLKEEFYSKADALIGVCPEHDDYMFSRVLTLDLTQYPEDEEAAENHKRTSLE", "length": 1243, "header": "tr|F1NX72-1|F1NX72_CHICK Isoform 1 of Structural maintenance of chromosomes protein OS=Gallus gallus OX=9031 GN=SMC1B PE=1 SV=3 CANONICAL=F1NX72-1" }, "isoforms": [ { "isoform_ac": "F1NX72-1", "url": "https://www.uniprot.org/uniprotkb/F1NX72/entry#F1NX72-1", "sequence": { "sequence": "MASAPTATGLGYLKLLMVKDFKSWRGEQLIGPFMRFNCIIGPNGSGKSNIMDAVSFVLCEKISNLRVKSVRELIHGAHVGKPVSSTASVKIVYCEEDGEEKTFSRVIRDGCSEYIFNDKSITRSAYISELEKIGILVKARNCLIFQGTVESIAMKKPKERTQLFEQISNSWQYAEEYERKKKKMQQAEEDAHFNYNKKKNIAAERKQAKVEKEEAEHYQMLVRELNANRVQLQLFQLYHNERSIESLKESLDEKNMEARIKKDSLSTAEDTFRAKKKVLGVLNRDQQQMEREMKTLQASLIQQKALYIKAKENTSYQIKKVEMSKRSLRDKEKYCDKEKQNIKELEMELHDTEKAWREFEKEAEEEILLRVERVELRERQLERYKELKEIARRKVATLTQQLGKLRWEQKADEERMKLYQRKKKEVKETIVQTVEQIEEYKKRVEKLEEYTKKCTESLEEEKKKEEMLAKEIENSTTRIAEVNEELNKIVGELQNARIDYHEGKRQQMRAEIVESLKRLYPDSVFGRLLDLCHPIHKKYQLAVTKVFSKYMTAIVVATEKTARDCIQFLKQERAEPETFLALDYLEVKPINERLREIKGAKMIVDVVQTPFAPLKRVIQFVSGNGLVCDTVKEARQIAFEGPVRLKTVALDGTLFLKSGVISGGSSDLRVKARCWDDKEINRMKERRDALITELKDLMKIKRKEADLKQLQAQCHGTQTRLKYSQSELDLIKKKHLPNVYMEKSKLESELVNTESQHDMIKEGVVQRKLKIEEFQKQINEAEDAVFQEFCEEIGIENIRVYEQEHVRRQEEIDKRRLEFENQKTRLSVQLEYNREHLQKLTDAVSKLRDTIHKDESEIAGLQKDEEKHLKRVNEIEEEEQHLKDRLSAQKSEIMKTQSEADELRKTLLTLNREAAKLQKEAAAIEASLEDKRLRRHNMLLECKVQDLKIRLLFGSLDDISEVELGTETEDTQTTGIYEREEAIKIDYSSLPKDLKDLESDKEIEAHLNQMQQEIKSKESILMKTAVPNLRAVEKLQIARNKFQESMEAFEASRKEARISKQEFEEVKKRRYELFSQCFEHASIVIDQVYKKLCRNSSAQAFLSPENPEEPYLEGIGFNCVAPGKRFMPMDSLSGGEKTVAALALIFAVHSFRPAPFFILDEIDAALDNTNIDKVSIFIREQAHKQFQMVVISLKEEFYSKADALIGVCPEHDDYMFSRVLTLDLTQYPEDEEAAENHKRTSLE", "length": 1243, "header": "tr|F1NX72-1|F1NX72_CHICK Isoform 1 of Structural maintenance of chromosomes protein OS=Gallus gallus OX=9031 GN=SMC1B PE=1 SV=3 CANONICAL=F1NX72-1" }, "locus": { "chromosome": "1", "start_pos": 70481832, "end_pos": 70445780, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029015.1", "url": "https://www.ensembl.org/id/ENSGALT00010029015.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016774.1", "url": "https://www.ensembl.org/id/ENSGALP00010016774.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:418243", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418243", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2MZS5-1", "protein_name": "Structural maintenance of chromosomes protein", "gene_name": "Smc1b", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MGRLELLLVENFKSWRGRQVIGPFKRFTCIIGPNGSGKSNVMDALSFVMGEKTTNLRVKNIQELIHGAHIGKPVSSSASVKIIYIEDNGEEKTFTRIIRGGCSEFHFGDKPVSRSAYVAQLEKIGIIVKAQNCLVFQGTVESISMKKPKERTQFFEEISTSGEFIGEYEAKKKKLQKAEEDAQFNFNRKKNVAAERKHAKIEKEEAEHYQSLLKELKINKIQLMLFQLYYNEEKINVLNTELEHKDKSLSVVKDTLSHHESIIKAKKKDHGMLTRQLQQTEKELKSLEAILNQKRPQYIKAKENTSHHLKKLDLSKKLITDNEKQCSKQEDDIRALEEELVDLDRAWRSFEKQMEEKILHKGKDIELENSQLDRYKELKEQVRRKVAIMTQQLEKLQWEQKAEKERLAFEKRRHGDTQGNLKQIKEQIEEHKKRIEKLEEYTKTCMDCLKDKKQQEEALIKEIDDTKSRMSEVNEELSLIRSELQNAGIDNHEGKRQRKRAEVLEHLKRLYPDSVFGRLLDLCHPIHKKYQLAVTKLFGRYMVAIVVASEKVAKDCIQFLKEERAEPETFLALDYLDIKPINERLREIKGCKMMIDVIKTQFPQLKKVIQFVCGNGLVCETVEEARHIAFGGPERRKAVALDGTLFLKSGVISGGSSDLKHKALCWDEKELHSLRDKRGQLVQELKELMKTLRKEADLKQIQTLVQGTNTRLKYSQNELEMIKKKHLAAFYREQSQLQSELLNIESQCTMLNEGINKQQQKIEEFQDKIDKVEDEIFQDFCEEIGVENIREFENKHVKQQQENDQKRLEFEKQKTRLNIQLEYSRNQLKKKLNKIATLKMTIQKGREDIDNLKKTEEECLRSVDELMMKQEQVKEVFATQSSNIEKIHIQIEEERKKFLAVDRDVGKLQKEVVIIQGSLEQKLLEKHNLLLDCKVQDIEINLVLGSLEDIIEVELTETESTQATADIYEKEASIQVDYSPLREDLKALQSDKEVEDHLTLLREQVASQENTLLKTSAPNLRAQENLKAVRDKFQESADAFEASRKEARVCRQEFEQVKRRRYDAFSQCFEHISISIDQIYKKLCRNSSAQAFLSPENPEEPYLDGISYNCVAPGKRFMPMDNLSGGEKCVAALALLFAVHSFRPAPFFVLDEVDAALDNTNIGKVSSYIKEQSQEQFQMIVISLKEEFYSRADALIGIYPEHDECMFSHVLTLDLSKYPDTEDQESSRRRRKPRASQSPQSPQSR", "length": 1245 }, "evidence": [ { "id": "F1NX72", "url": "https://omabrowser.org/oma/group/F1NX72/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0AAA9U157-1", "protein_name": "Structural maintenance of chromosomes protein", "gene_name": "SMC1B", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSRLEVLFVENFKSWRGRQVIGPFKRFTCIIGPNGSGKSNVMDALSFVMGEKIANLRVKNIQELIHGAHIGKPVSSSASVKIVYLEESGEEKTFARTIRGGCSEYSFNDNPMSRSAYITELEKIGIIVKARNCLVFQGTVESISMKKPKERTQFFEEISTSGELIGEYEEKKRKLHKAEEDAQFNFNKKKNVAAERKHAKLEKEEADRYQNLLEELKINKIQLQLFRLYHNEKKINFLYTELERVNKNLSVTRESLSHHENIVKAKKKEHGMLSRQLQQTQKELKSLEALLNQKRPQYIKAKENTSHHLKKLDMAKKSIKDSEKQCSKQEDDIKALETELADLDGAWRSFEKQIEEEMLHKGRDIELEAGQLVQYKELKEQVRKKVAIMTQQLEKLQWEQRSDEERWAFEKRRHGEVQENIKQIKEQIEDHKKRIEKLEEYTKTCTNCLKEKKEQEENLVNEIEKTKSRMSEVNEELNLIRSELQNAGIDTHEGKRQQKRAEILEHLKRLYPDSVFGRLLDLCHPIHKKYQLAVTKLFGRYMVAIVVASEKVAKDCIRFLKEERAEPETFLALDYLDIKPINERLREIKGCKMMIDVIKTQFPQLKKVIQFVCGNGLVCETLEEARHIAFAGPERRKTVALDGTLFLKSGVISGGSSDLKSKARCWDEKELKNLRDRRTQLIQELKDLMKIVRKEADLKQIQALIQGTTTRLKYAQSELEIIKKKHLAAFYREQSQLQSELLNIESQCAMLSEGIKERQQRIKEFQRKIDKVEDDIFQHFCEEIGVENIREFENKHIKQQQEADQKRLEFEKQKTRLNIQLEYSRNHLKKKLNKINTLKEAIEKGREDTDHLKKVEENCLKIVDELMEKQQQLKDEFVTQNTNVEKVQAQIEEERKKFLAIDREVGKWQKEVVILQSSLEQNRLEKHNMLLDCKVQDIEIVLLLGSLDDIIEVELGTEAEGTQATTDIYEKEAAIEVDYSSLREDLKALQSDKEIEAQLRLLLQQVASQEDILLKTAAPNLRAVENLKTVRDKFQESIDAFEASRKEARICRQEFEQVKKRRYDLFNQCFEHISISIDQIYKKLCRNNSAQAFLSPENPEEPYLEGISYNCVAPGKRFMPMDNLSGGEKCVAALALLFAVHSFRPAPFFVLDEVDAALDNTNIGKVSSYIKEQTQEQFQMIIISLKEEFYSKADALIGIYPEYDDCMFSRVLTLDLSQYPDTEGRESSRRQRKPH", "length": 1235 }, "evidence": [ { "id": "F1NX72", "url": "https://omabrowser.org/oma/group/F1NX72/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "D3ZE73-1", "protein_name": "Structural maintenance of chromosomes protein", "gene_name": "Smc1b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGHLELLLVENFKSWRGRQVIGPFKRFTCIIGPNGSGKSNVMDALSFVMGEKTTNLRVKNIQELIHGAHIGKPVSSSASVTIIYVEDSGEEKTFTRIIRGRGGCSEFHFGDKPVSRSVYVAQLENIGIIVKAQNCLVFQGTVESISMKKPKERTQFFEEISTSGEFIGEYEAKKKKLQKAEEDAQFHFNRKKNVAAERKHAKIEKEEAEHYQSLLEELKTNKIQLMLFQLYYNEEKINVLNTELEHMDRNLSVVKDTLSHHENIIKAKKKDYGMLTRQLQQTAKELKSVEAVLNQKRPQYIKAKENTSHHLKKLDLSKKLITDNEKQCAKQEDGIRALVAELVDLDRAWRSFEKQMEEKILHKGRDIELENSQLDRYKELKEQVRRRVGIMTQQLEKLQWEQKAEKERLAFERRRHGDTQGNLKQIKEQIEEHKKRIEKLEEYTKTCMDCLEDKKQQEEALIKEIDNTKSRMSEVNEELSLIRNELQNAGIDNHEGKRQRKRAEVLEHLKRLYPDSVFGRLLDLCHPIHKKYQLAVTKLFGRYMVAIVVASEKVAKDCIRFLKEERAEPETFLALDYLDIKPINERLREIKGCKMMIDVIKTQFPQLKKVIQFVCGNGLVCETVEEARHIAFGGPERRKAVALDGTLFLKSGVISGGSSDLKHKALCWDEKELHSLRDKRNQLVQELKELMKTLRKETDLKQIQALVQGTNTRLKYSQNELEMIKKKHLATFYREQSQLQSELLNIDSQCTMLSEGINKQQQKIEEFQDKIDKVEDDIFQDFCEEIGVENIREFENKHVKQQQENDQKRLEFEKQKTRLNIQLEYSRNQLKKKLNKIDTLKTTIQKGREDIDNLKKTEEECLKIVEELMVKQEQVKEVLATQSSNIEKIHIQIEEERKKFLAVDREVGKLQKEVVIIQGSLEQKQLEKHNLLLDCKVQDIDISLMLGSLEDIIEVELTETESTQATADIYEKEASIQIDYSPLREDWKALQSDKEVEAHLTLLLQQVASQENTLLKTAAPNLRAQENLKAVRDKFQESADAFEASRKEARICRQEFEQVKRRRYDAFSQCFEHISVSIDQIYKKLCRNNSAQAFLSPENPEEPYLDGISYNCVAPGKRFMPMDNLSGGEKCVAALALLFAVHSFRPAPFFVLDEVDAALDNTNIGKVSGYIKEQSQEQFQMIIISLKEEFYSRADALIGVYPEHDECMFSHVLTLDLSKYPDTEDQEGSRSHRKPRARVSQSPQSPQSR", "length": 1249 }, "evidence": [ { "id": "F1NX72", "url": "https://omabrowser.org/oma/group/F1NX72/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q54E85-1", "protein_name": "Structural maintenance of chromosomes protein", "gene_name": "smc1", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MGISILKIQNFKSYKGNPLIGPFKDFSCVIGPNGRGKSNIMDAIIFVLGHNSSQIRSTKLNELVNTHIVTDKNNNEGGDNSTYVAINFNHQGNNYRFSRKIIGNGSQYFFEQTQVSAEQYQKHLKDIGIDIGTKNFFVFQGDVESIATQNPKQISAFIDDISGSRALKFEYDRLLGEKSKCEDDVFASYAKRKTIAFEKEQYKEQWTEVKEYQSMQDRVDSLKTDQQLAKLYQTTKEMRKEQKLLDESKQQIQSIQSDEMKPLEQQYTQTSKNQASLHKEVVQLEDDISRLIKGKKKKGSDQYSAEEEIKYISEKIKKTKLILSKAENSRSKQIQEIDQLRNELNEFTEQLENLDDEKEVAETGLSIKMDHQQIEEYNQLKLQSGKETSGLKIKYDQLSREHKIEQDQHQQLTYRLEEFETMKKKFQESKEKFQNQKDIEQSNFQDLEQKLKESEKELVQCTTRFNETQQRQQNLNNDLERIQYSLSDLKSLKSESQRDRQFNQTVETLKSIFPGVKGKLMDLCEPSQRKYATALTLTMGKLMDAIIVDTEETLIGCVRYLKEQLLGVATFISLDRLQMVKPINQQLRQISGGGGGSTAKLLFDCLKIQKGIEDAVLYALGNTVVCESLAEAKLLAFGGKDRVKVITIQGIRITKSGLMSGGGLSSIKSKSSQWDTKRVEELKKQRDTILAELSDVIQLNEIFNQRQQLTSQVHQLKSDYSLSKSKIELLNDRLKKNQQELETNEKVINETIIPELSELNETLAKRKTQLDQLQSEINSIEERYFSGFSKKFGVDNIREYEDNRLAKIQENIQKRLSLTESISVIQSRLDYEQGREIDNEIKQLSEELNANEKILDQELEHKKENDEKEKQFKENLSDLQKQHTEKKSQLDKMNITIKDLKKQLSTFNNQITDIEKLSNRHDFNITKLRGVYHQILIETRNEDIRLPILQFKGKEIDQGNNNNNNNNNNNNNNNNNNNDKSEGETEDNNKKQKNKDSEAEVDESAVSEGENVKKPKKPTIKKKKSSIKRKRETNKGDQEDNQEEDEEDEDDIFNESDVEENEKPNILQDIIKDITQAMVQDDILDIYEDEASIKFNYSSLKKRVFVDQKTYEEYLRKLTIDIETIGKEMKRVMPNYKAYEHLVDVSDKLKKVRKELNQARDNAKTKIDSFNRVRDQRKQLFLRAFKRIAKNLTSIYSELTRELEPPYHRGSAHLALEDTENPFNSGVRFTVIPPNKRFQEMDQLSGGEKSVAALAFLFSTHGLKSTPFMILDEIDAAFDSVNVLKLVRYVRHKASKDLQFLVISLKEQFFVHSDLLVGVCREPDSQSKSFHLLLEEFPESDEAKKALISKGDDETETDGKTSATSGSSESEND", "length": 1373 }, "evidence": [ { "id": "F1NX72", "url": "https://omabrowser.org/oma/group/F1NX72/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q8NDV3-3", "protein_name": "Structural maintenance of chromosomes protein 1B", "gene_name": "SMC1B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAHLELLLVENFKSWRGRQVIGPFRRFTCIIGPNGSGKSNVMDALSFVMGEKIANLRVKNIQELIHGAHIGKPISSSASVKIIYVEESGEEKTFARIIRGGCSEFRFNDNLVSRSVYIAELEKIGIIVKAQNCLVFQGTVESISVKKPKERTQFFEEISTSGELIGEYEEKKRKLQKAEEDAQFNFNKKKNIAAERRQAKLEKEEAERYQSLLEELKMNKIQLQLFQLYHNEKKIHLLNTKLEHVNRDLSVKRESLSHHENIVKARKKEHGMLTRQLQQTEKELKSVETLLNQKRPQYIKAKENTSHHLKKLDVAKKSIKDSEKQCSKQEDDIKALETELADLDAAWRSFEKQIEEEILHKKRDIELEASQLDRYKELKEQVRKKVATMTQQLEKLQWEQKTDEERLAFEKRRHGEVQGNLKQIKEQIEDHKKRIEKLEEYTKTCMDCLKEKKQQEETLVDEIEKTKSRMSEVNEELNLIRSELQNAGIDTHEGKRQQKRAEVLEHLKRLYPDSVFGRLFDLCHPIHKKYQLAVTKVFGRFITAIVVASEKVAKDCIRFLKEERAEPETFLALDYLDIKPINERLRELKGCKMVIDVIKTQFPQLKKVIQFVCGNGLVCETMEEARHIALSGPERQKTVALDGTLFLKSGVISGGSSDLKYKARCWDEKELKNLRDRRSQKIQELKGLMKTLRKETDLKQIQTLIQGTQTRLKYSQNELEMIKKKHLVAFYQEQSQLQSELLNIESQCIMLSEGIKERQRRIKEFQEKIDKVEDDIFQHFCEEIGVENIREFENKHVKRQQEIDQKRLEFEKQKTRLNVQLEYSRSHLKKKLNKINTLKETIQKGSEDIDHLKKAEENCLQTVNELMAKQQQLKDIRVTQNSSAEKVQTQIEEERKKFLAVDREVGKLQKEVVSIQTSLEQKRLEKHNLLLDCKVQDIEIILLSGSLDDIIEVEMGTEAESTQATIDIYEKEEAFEIDYSSLKEDLKALQSDQEIEAHLRLLLQQVASQEDILLKTAAPNLRALENLKTVRDKFQESTDAFEASRKEARLCRQEFEQVKKRRYDLFTQCFEHVSISIDQIYKKLCRNNSAQAFLSPENPEEPYLEGISYNCVAPGKRFMPMDNLSGGEKCVAALALLFAVHSFRPAPFFVLDEVDAALDNTNIGKVSSYIKEQTQDQFQMIVISLKEEFYSRADALIGIYPEYDDCMFSRVLTLDLSQYPDTEGQESSKRHGESR", "length": 1235 }, "evidence": [ { "id": "F1NX72", "url": "https://omabrowser.org/oma/group/F1NX72/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q920F6-1", "protein_name": "Structural maintenance of chromosomes protein 1B", "gene_name": "Smc1b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGHLELLLVENFKSWRGRQVIGPFKRFTCIIGPNGSGKSNVMDALSFVMGEKTTNLRVKNIQELIHGAHTGKPVSSSASVTIIYIEDSGEEKTFTRIIRGGCSEYHFGDKPVSRSVYVAQLENIGIIVKAQNCLVFQGTVESISMKKPKERTQFFEEISTSGEFIGEYEAKKKKLQKAEEDAQFHFNVKKNVAAERKHAKIEKEEAEHYQNLLEELKINKIQLMLFQLYYNEEKINVLNTELEQMDGNLSVVKDTLSHHENIFKAKKKDYGMLTRQLQQTAKELKSVEAILNQKRPQYIKAKENTSHHLKKLDLSKKLITDNEKQCSKQEDGIRALVAELADLDRAWKSFEKQMEEKILQKGRDIELENSQLDRYKLLKEQVRRKVGIMTQQLEKLQWEQKAEKERLAFEKRRHGDTQGNLKQIKEQIEEHKKRIEKLEEYTKTCMDCLEDKKQQEEALKKEIENTKSRMSEVNEELSLIRNELQNAGIDNHEGKRQQKRAEVLEHLKRLYPDSVFGRLLDLCHPIHKKYQLAVTKLFGRYMVAIVVASEKIAKDCIRFLKAERAEPETFLALDYLDIKPINERLREIKGCKMMIDVIKTQFPQLKKVIQFVCGNGLVCETVEEARHIAFGGPERRKAVALDGTLFLKSGVISGGSSDLKHKALCWDEKELHNLRDKRSQLVQELKELMKTLRKETDLKQIQTLVQGTNTRLKYSQNELEMIKKKHLATFYREQSQLQSELLNIDSQCTMLSEGINKQQQKIEEFQDKIDEVEDDIFQDFCEEIGVENIREFENKHVKQQQENDQKRLEFEKQKTRLNIQLEYSRNQLKKKLNNIDTLKTTIQKGKEDIDNLKKTEEECLKIVEELMVKQEQIKEVLATQSSNIEKIHIQIEEERKKVLAVDREVGKLQKEVVIIQGSLEQKLLEKHNLLLDCKVQDIDISLVLGSLEDIIEMELTETESTQATADIYEKEASIQIDYSPLREDLKALQSDKEVEAHLTLLLQQVASQENTLLKTTAPNLRAQENLKTVRDKFQESADVFEASRKEARICRQEFEQVKRRRYDAFSQCFEHISVSIDQIYKKLCRNNSAQAFLSPENPEEPYLDGISYNCVAPGKRFMPMDNLSGGEKCVAALALLFAVHSFRPAPFFVLDEVDAALDNTNIGKVSSYIKEQSQEQFQMIIISLKEEFYSKADALIGVYPEHNECMFSHVLTLDLSKYPDTEDQEGSRSHRKPRVPRVSMSPKSPQSR", "length": 1248 }, "evidence": [ { "id": "F1NX72", "url": "https://omabrowser.org/oma/group/F1NX72/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "meiotic cohesin complex", "id": "GO:0030893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030893", "evidence": [ { "database": "UniProtKB", "id": "F1NX72", "url": "https://www.uniprot.org/uniprotkb/F1NX72" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1NX72", "url": "https://www.uniprot.org/uniprotkb/F1NX72" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "F1NX72", "url": "https://www.uniprot.org/uniprotkb/F1NX72" } ], "pmid": "" }, { "name": "chromosome, centromeric region", "id": "GO:0000775", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000775", "evidence": [ { "database": "UniProtKB", "id": "F1NX72", "url": "https://www.uniprot.org/uniprotkb/F1NX72" } ], "pmid": "" }, { "name": "lateral element", "id": "GO:0000800", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000800", "evidence": [ { "database": "UniProtKB", "id": "F1NX72", "url": "https://www.uniprot.org/uniprotkb/F1NX72" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "F1NX72", "url": "https://www.uniprot.org/uniprotkb/F1NX72" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "F1NX72", "url": "https://www.uniprot.org/uniprotkb/F1NX72" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "F1NX72", "url": "https://www.uniprot.org/uniprotkb/F1NX72" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "sister chromatid cohesion", "id": "GO:0007062", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007062", "evidence": [ { "database": "UniProtKB", "id": "F1NX72", "url": "https://www.uniprot.org/uniprotkb/F1NX72" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1095, "end_pos": 1097, "annotation": "n_glycosylation_sequon" }, { "start_pos": 313, "end_pos": 315, "annotation": "n_glycosylation_sequon" }, { "start_pos": 43, "end_pos": 45, "annotation": "n_glycosylation_sequon" }, { "start_pos": 474, "end_pos": 476, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1NX72-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 1243, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1NX72-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1NX72" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1095, "end_pos": 1097 }, { "start_pos": 313, "end_pos": 315 }, { "start_pos": 43, "end_pos": 45 }, { "start_pos": 474, "end_pos": 476 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1NXP1-1", "uniprot_ac": "F1NXP1", "uniprot_id": "F1NXP1_CHICK", "mass": { "chemical_mass": 51999.0, "monoisotopic_mass": 51999.0 }, "refseq": { "ac": "NP_001378918", "name": "inositol-trisphosphate 3-kinase A", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001378918" }, "gene_names": [ { "name": "ITPKA", "type": "recommended", "evidence": [ { "id": "F1NXP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NXP1" } ] }, { "name": "IP3KA", "type": "synonym", "evidence": [ { "id": "NP_001378918", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001378918" } ] }, { "name": "ITPKA", "type": "synonym", "evidence": [ { "id": "NP_001378918", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001378918" } ] } ], "protein_names": [ { "name": "Kinase", "type": "recommended", "evidence": [ { "id": "F1NXP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NXP1/entry#names_and_taxonomy" } ] }, { "name": "2.7.-.-", "type": "synonym", "evidence": [ { "id": "F1NXP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NXP1/entry#names_and_taxonomy" } ] }, { "name": "inositol 1,4,5-trisphosphate 3-kinase A", "type": "synonym", "evidence": [ { "id": "NP_001378918", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001378918" } ] }, { "name": "inositol-trisphosphate 3-kinase A", "type": "synonym", "evidence": [ { "id": "NP_001378918", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001378918" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000214.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001378918", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001378918" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NXP1", "url": "https://www.uniprot.org/uniprotkb/F1NXP1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ITPKA", "url": "https://www.uniprot.org/uniprotkb/F1NXP1", "locus": { "chromosome": "5", "start_pos": 24229171, "end_pos": 24191313, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010022541", "url": "https://www.ensembl.org/id/ENSGALG00010022541" } ] } } ], "crossref": [ { "id": "F1NXP1", "url": "https://alphafold.ebi.ac.uk/entry/F1NXP1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000008603", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000008603", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "395694", "url": "https://www.ncbi.nlm.nih.gov/gene/395694", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR005522", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005522", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038286", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038286", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "FQVFVEF", "url": "https://omabrowser.org/oma/group/FQVFVEF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZNX6", "url": "https://www.orthodb.org/?gene=A0A8V0ZNX6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NXP1", "url": "https://www.orthodb.org/?gene=F1NXP1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12400", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12400", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12400:SF55", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12400:SF55", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03770", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03770", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001378918", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001378918", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "11020", "url": "https://www.rhea-db.org/rhea/11020", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0ZNX6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNX6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZNX6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNX6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NXP1", "url": "https://www.uniprot.org/uniprotkb/F1NXP1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NXP1-1", "url": "https://www.uniprot.org/uniprotkb/F1NXP1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MHAPGRRPWGSARRAPAADPGAEPRAALHDSPDLSRATRLSVGELRSLFEARCAAVAAAAARQLPDPAKRGCRPPNGVLPPVIPRLTVTAEESEESQGSPKAPPAHPEGGWLRTDSSLHLQSRRLSTSSLSSTGSSSLLEDSEDDVLSDTECRSQGIVHLERGEDSNQKKAWHTIKTMVNLPVISPFKKRYSWVQLAGHTGSFKAADSGKILKRFSENEKECFERLMKDPLRSCVPCFHGVVERDGETYIQLDDLLTDFEGPCVMDCKMGIRTYLEEELTKAREKPKLRKDMYKKMIEVDPLAPTAEENAQHAVTKPRYMQWRETISSSANLGFRIEGIKKADGTCNTNFKTTKTQEQVLQVFVEFIEGNTTILKKYLKRLQEIHIILESSDFFKRHEVVGSSLLFVHDGSGNANVWLIDFGKTTLLPDGQTLDHRIPWQEGNREDGYLLGLDNLIRILESITER", "length": 465, "header": "tr|F1NXP1-1|F1NXP1_CHICK Isoform 1 of Kinase OS=Gallus gallus OX=9031 GN=ITPKA PE=3 SV=2 CANONICAL=F1NXP1-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZNX6-1", "url": "https://www.uniprot.org/uniprotkb/F1NXP1/entry#A0A8V0ZNX6-1", "sequence": { "sequence": "GGKAGGEAAPGKRRPVGELRSLFEARCAAVAAAAARQLPDPAKRGCRPPNGVLPPVIPRLTVTAEESEESQGSPKAPPAHPEGGWLRTDSSLHLQSRRLSTSSLSSTGSSSLLEDSEDDVLSDTECRSQGIVHLERGEDSNQKKAWHTIKTMVNLPVISPFKKRYSWVQLAGHTGSFKAADSGKILKRFSENEKECFERLMKDPLRSCVPCFHGVVERDGETYIQLDDLLTDFEGPCVMDCKMGIRTYLEEELTKAREKPKLRKDMYKKMIEVDPLAPTAEENAQHAVTKPRYMQWRETISSSANLGFRIEGIKKADGTCNTNFKTTKTQEQVLQVFVEFIEGNTTILKKYLKRLQEIHIILESSDFFKRHEVVGSSLLFVHDGSGNANVWLIDFGKTTLLPDGQTLDHRIPWQEGNREDGYLLGLDNLIRILESITER", "length": 439, "header": "tr|A0A8V0ZNX6-1|A0A8V0ZNX6_CHICK Computationally mapped isoform of Kinase OS=Gallus gallus OX=9031 GN=ITPKA PE=3 SV=1 CANONICAL=F1NXP1-1" }, "locus": { "chromosome": "5", "start_pos": 24225111, "end_pos": 24191404, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054872.1", "url": "https://www.ensembl.org/id/ENSGALT00010054872.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033170.1", "url": "https://www.ensembl.org/id/ENSGALP00010033170.1" } ] } }, { "isoform_ac": "F1NXP1-1", "url": "https://www.uniprot.org/uniprotkb/F1NXP1/entry#F1NXP1-1", "sequence": { "sequence": "MHAPGRRPWGSARRAPAADPGAEPRAALHDSPDLSRATRLSVGELRSLFEARCAAVAAAAARQLPDPAKRGCRPPNGVLPPVIPRLTVTAEESEESQGSPKAPPAHPEGGWLRTDSSLHLQSRRLSTSSLSSTGSSSLLEDSEDDVLSDTECRSQGIVHLERGEDSNQKKAWHTIKTMVNLPVISPFKKRYSWVQLAGHTGSFKAADSGKILKRFSENEKECFERLMKDPLRSCVPCFHGVVERDGETYIQLDDLLTDFEGPCVMDCKMGIRTYLEEELTKAREKPKLRKDMYKKMIEVDPLAPTAEENAQHAVTKPRYMQWRETISSSANLGFRIEGIKKADGTCNTNFKTTKTQEQVLQVFVEFIEGNTTILKKYLKRLQEIHIILESSDFFKRHEVVGSSLLFVHDGSGNANVWLIDFGKTTLLPDGQTLDHRIPWQEGNREDGYLLGLDNLIRILESITER", "length": 465, "header": "tr|F1NXP1-1|F1NXP1_CHICK Isoform 1 of Kinase OS=Gallus gallus OX=9031 GN=ITPKA PE=3 SV=2 CANONICAL=F1NXP1-1" }, "locus": { "chromosome": "5", "start_pos": 24225111, "end_pos": 24191766, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054878.1", "url": "https://www.ensembl.org/id/ENSGALT00010054878.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033176.1", "url": "https://www.ensembl.org/id/ENSGALP00010033176.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "P17105-1", "protein_name": "Inositol-trisphosphate 3-kinase A", "gene_name": "Itpka", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTLPGHPTGMARPRGAGPCSPGLERAPRRSVGELRLLFEARCAAVAAAAAAGEPRARGAKRRGGQVPNGLPRAAPAPVIPQLTVTSEEDVAPASPGPPDREGNWLPAAGSHLQQPRRLSTSSLSSTGSSSLLEDSEDDLLSDSESRSRGNVQLETSEDVGQKSHWQKIRTMVNLPVMSPFKKRYSWVQLAGHTGSFKAAGTSGLILKRSSEPEHYCLVRLMADVLRGCVPAFHGVVERDGESYLQLQDLLDGFDGPCVLDCKMGVRTYLEEELTKARERPKLRKDMYKKMLAVDPEAPTEEEHAQRAVTKPRYMQWREGISSSTTLGFRIEGIKKADGSCSTDFKTTRSREQVTRVFEEFMQGDAEVLKRYLNRLQQIRDTLEISDFFRRHEVIGSSLLFVHDHCHRAGVWLIDFGKTTPLPDGQILDHRRPWEEGNREDGYLLGLDNLIGILANLAER", "length": 459 }, "evidence": [ { "id": "F1NXP1", "url": "https://omabrowser.org/oma/group/F1NXP1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P23677-1", "protein_name": "Inositol-trisphosphate 3-kinase A", "gene_name": "ITPKA", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTLPGGPTGMARPGGARPCSPGLERAPRRSVGELRLLFEARCAAVAAAAAAGEPRARGAKRRGGQVPNGLPRAPPAPVIPQLTVTAEEPDVPPTSPGPPERERDCLPAAGSSHLQQPRRLSTSSVSSTGSSSLLEDSEDDLLSDSESRSRGNVQLEAGEDVGQKNHWQKIRTMVNLPVISPFKKRYAWVQLAGHTGSFKAAGTSGLILKRCSEPERYCLARLMADALRGCVPAFHGVVERDGESYLQLQDLLDGFDGPCVLDCKMGVRTYLEEELTKARERPKLRKDMYKKMLAVDPEAPTEEEHAQRAVTKPRYMQWREGISSSTTLGFRIEGIKKADGSCSTDFKTTRSREQVLRVFEEFVQGDEEVLRRYLNRLQQIRDTLEVSEFFRRHEVIGSSLLFVHDHCHRAGVWLIDFGKTTPLPDGQILDHRRPWEEGNREDGYLLGLDNLIGILASLAER", "length": 461 }, "evidence": [ { "id": "F1NXP1", "url": "https://omabrowser.org/oma/group/F1NXP1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8R071-1", "protein_name": "Inositol-trisphosphate 3-kinase A", "gene_name": "Itpka", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTLPGRPTGMARPRGAGPCSPGLERAPRRSVGELRLLFEARCAAVAAAAAAGEPRARGAKRRGGQVPNGLPRAAPAPVIPQLTVTSEEDVTPASPGPPDQEGNWLPAAGSHLQQPRRLSTSSLSSTGSSSLLEDSEDDLLSDSESRSRGNVQLETSEDVGQKSHWQKIRTMVNLPVMSPFRKRYSWVQLAGHTGSFKAAGTSGLILKRSSEPEHYCLVRLMADVLRGCVPAFHGIVERDGESYLQLQDLLDGFDGPCVLDCKMGVRTYLEEELTKARERPKLRKDMYKKMLAVDPEAPTEEEHAQRAVTKPRYMQWREGISSSTTLGFRIEGIKKADGSCSTDFKTTRSREQVTRVFEEFMQGDAEVLRRYLNRLQQIRDTLEISDFFRRHEVIGSSLLFVHDHCHRAGVWLIDFGKTTPLPDGQILDHRRPWEEGNREDGYLLGLDNLIGILASLAER", "length": 459 }, "evidence": [ { "id": "F1NXP1", "url": "https://omabrowser.org/oma/group/F1NXP1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "inositol hexakisphosphate kinase activity", "id": "GO:0000828", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000828", "evidence": [ { "database": "UniProtKB", "id": "F1NXP1", "url": "https://www.uniprot.org/uniprotkb/F1NXP1" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "F1NXP1", "url": "https://www.uniprot.org/uniprotkb/F1NXP1" } ], "pmid": "" }, { "name": "inositol-1,4,5-trisphosphate 3-kinase activity", "id": "GO:0008440", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008440", "evidence": [ { "database": "UniProtKB", "id": "F1NXP1", "url": "https://www.uniprot.org/uniprotkb/F1NXP1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1NXP1", "url": "https://www.uniprot.org/uniprotkb/F1NXP1" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1NXP1", "url": "https://www.uniprot.org/uniprotkb/F1NXP1" } ], "pmid": "" }, { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "F1NXP1", "url": "https://www.uniprot.org/uniprotkb/F1NXP1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "cellular response to calcium ion", "id": "GO:0071277", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071277", "evidence": [ { "database": "UniProtKB", "id": "F1NXP1", "url": "https://www.uniprot.org/uniprotkb/F1NXP1" } ], "pmid": "" }, { "name": "phosphatidylinositol phosphate biosynthetic process", "id": "GO:0046854", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046854", "evidence": [ { "database": "UniProtKB", "id": "F1NXP1", "url": "https://www.uniprot.org/uniprotkb/F1NXP1" } ], "pmid": "" }, { "name": "inositol phosphate biosynthetic process", "id": "GO:0032958", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032958", "evidence": [ { "database": "UniProtKB", "id": "F1NXP1", "url": "https://www.uniprot.org/uniprotkb/F1NXP1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 370, "end_pos": 372, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "11020", "name": "", "equation": "1D-myo-inositol 1,4,5-trisphosphate + ATP = 1D-myo-inositol 1,3,4,5-tetrakisphosphate + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0Z4Z4-1", "F1NXP1-1" ], "evidence": [ { "id": "11020", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/11020" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A8V0Z4Z4", "gene_name": "ITPKC", "activity": [ { "ec_number": "2.7.-.-", "activity": "", "evidence": [ { "id": "A0A8V0Z4Z4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4Z4" } ] } ] }, { "uniprot_ac": "F1NXP1", "gene_name": "ITPKA", "activity": [ { "ec_number": "2.7.-.-", "activity": "", "evidence": [ { "id": "F1NXP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NXP1" } ] } ] } ], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1NXP1-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 465, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1NXP1-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1NXP1" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], 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"count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1NXY9-1", "uniprot_ac": "F1NXY9", "uniprot_id": "F1NXY9_CHICK", "mass": { "chemical_mass": 38487.0, "monoisotopic_mass": 38487.0 }, "refseq": { "ac": "XP_425790", "name": "protein L-Myc", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_425790" }, "gene_names": [ { "name": "MYCL", "type": "recommended", "evidence": [ { "id": "F1NXY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NXY9" } ] }, { "name": "MYCL", "type": "synonym", "evidence": [ { "id": "XP_425790", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_425790" } ] } ], "protein_names": [ { "name": "MYCL proto-onco, bHLH transcription factor", "type": "synonym", "evidence": [ { "id": "F1NXY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NXY9/entry#names_and_taxonomy" } ] }, { "name": "protein L-Myc", "type": "synonym", "evidence": [ { "id": "XP_425790", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_425790" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052554.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Dec 16, 2011 this sequence version replaced XP_425790.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_425790", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_425790" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NXY9", "url": "https://www.uniprot.org/uniprotkb/F1NXY9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MYCL", "url": "https://www.uniprot.org/uniprotkb/F1NXY9", "locus": { "chromosome": "23", "start_pos": 5895643, "end_pos": 5899566, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010016453", "url": "https://www.ensembl.org/id/ENSGALG00010016453" } ] } } ], "crossref": [ { "id": "F1NXY9", "url": "https://alphafold.ebi.ac.uk/entry/F1NXY9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000024047", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000024047", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd11457", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11457", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "428231", "url": "https://www.ncbi.nlm.nih.gov/gene/428231", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002418", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002418", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011598", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011598", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012682", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012682", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036638", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036638", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050433", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050433", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:428231", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:428231", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CGRNYAS", "url": "https://omabrowser.org/oma/group/CGRNYAS/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1NXY9", "url": "https://www.orthodb.org/?gene=F1NXY9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45851", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45851", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00010", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00010", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01056", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01056", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_425790", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_425790", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1NXY9", "url": "https://www.uniprot.org/uniprotkb/F1NXY9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NXY9-1", "url": "https://www.uniprot.org/uniprotkb/F1NXY9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MERDAYQHYLYDYDAGEDFHRSTAPSEDIWKKFEFVPTPPLSPLGERPGCSAAEERGCPPRCCLPDEPEYLIGTGQLFGNLSAFILRDCMWSGFSARERLEKAMTEKLSTGTPRAAPHKPSSAPDLGFGSSVSECVDPAAVFLCPLAESKVPPSSGSEGQSDSEGEEIDVVTVEKRQSLSLRKPVTITLRADPLDPCMKHFHISIHQQQHNYAARSPPDACPQPKSPQQDEEELLSAAEPPPSHALPDPGLPKAGPGSDSEDVAKRKNHNYLERKRRNDLRSRFLALRDQVPGLASCPKTPKVVILSKSSEYLQSLISAERRMAAEKRQLRLRQMQLLRQIAQLKGH", "length": 347, "header": "tr|F1NXY9-1|F1NXY9_CHICK Isoform 1 of MYCL proto-onco, bHLH transcription factor OS=Gallus gallus OX=9031 GN=MYCL PE=4 SV=3 CANONICAL=F1NXY9-1" }, "isoforms": [ { "isoform_ac": "F1NXY9-1", "url": "https://www.uniprot.org/uniprotkb/F1NXY9/entry#F1NXY9-1", "sequence": { "sequence": "MERDAYQHYLYDYDAGEDFHRSTAPSEDIWKKFEFVPTPPLSPLGERPGCSAAEERGCPPRCCLPDEPEYLIGTGQLFGNLSAFILRDCMWSGFSARERLEKAMTEKLSTGTPRAAPHKPSSAPDLGFGSSVSECVDPAAVFLCPLAESKVPPSSGSEGQSDSEGEEIDVVTVEKRQSLSLRKPVTITLRADPLDPCMKHFHISIHQQQHNYAARSPPDACPQPKSPQQDEEELLSAAEPPPSHALPDPGLPKAGPGSDSEDVAKRKNHNYLERKRRNDLRSRFLALRDQVPGLASCPKTPKVVILSKSSEYLQSLISAERRMAAEKRQLRLRQMQLLRQIAQLKGH", "length": 347, "header": "tr|F1NXY9-1|F1NXY9_CHICK Isoform 1 of MYCL proto-onco, bHLH transcription factor OS=Gallus gallus OX=9031 GN=MYCL PE=4 SV=3 CANONICAL=F1NXY9-1" }, "locus": { "chromosome": "23", "start_pos": 5899411, "end_pos": 5896583, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010039629.1", "url": "https://www.ensembl.org/id/ENSGALT00010039629.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010022888.1", "url": "https://www.ensembl.org/id/ENSGALP00010022888.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:428231", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:428231", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "G3V7T4-1", "protein_name": "MYCL proto-oncogene, bHLH transcription factor", "gene_name": "Mycl", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MCVCAGCRASPSRRGAAPLQVAGGGSEGADMDFDSYQHYFYDYDCGEDFYRSTAPSEDIWKKFELVPSPPTSPPWGSGPGAVDPASGISPGEPWPGGGAGDEAESRGHSKAWGRNYASIIRRDCMWSGFSARERLERVVSDRLAPGVPRGNPPKAPATPDGTPSLEASNPAPATQCQLGEPKTQACSGSESPSDSEGEEIDVVTVEKRRSLDIRKPVTITVRADPLDPCMKHFHISIHQQQHNYAARFPPESCSQEGDPEPGAQEEALEIEAPKEKEEEEEEEEEEEEIVSPPPVENEAPQSCHPKPVSSDTEDVTKRKNHNFLERKRRNDLRSRFLALRDQVPTLASCSKAPKVVILSKALEYLQALVGAEKKMATEKRQLRCRQQQLQKRIAYLSGY", "length": 399 }, "evidence": [ { "id": "F1NXY9", "url": "https://omabrowser.org/oma/group/F1NXY9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P12524-1", "protein_name": "Protein L-Myc", "gene_name": "MYCL", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDYDSYQHYFYDYDCGEDFYRSTAPSEDIWKKFELVPSPPTSPPWGLGPGAGDPAPGIGPPEPWPGGCTGDEAESRGHSKGWGRNYASIIRRDCMWSGFSARERLERAVSDRLAPGAPRGNPPKASAAPDCTPSLEAGNPAPAAPCPLGEPKTQACSGSESPSDSENEEIDVVTVEKRQSLGIRKPVTITVRADPLDPCMKHFHISIHQQQHNYAARFPPESCSQEEASERGPQEEVLERDAAGEKEDEEDEEIVSPPPVESEAAQSCHPKPVSSDTEDVTKRKNHNFLERKRRNDLRSRFLALRDQVPTLASCSKAPKVVILSKALEYLQALVGAEKRMATEKRQLRCRQQQLQKRIAYLTGY", "length": 364 }, "evidence": [ { "id": "F1NXY9", "url": "https://omabrowser.org/oma/group/F1NXY9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q1LWL8-1", "protein_name": "Protein L-Myc-1b", "gene_name": "mycl1b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MPGISASASRIKKWEMEEYDQYQHYFYDDHNLDEDFFKSTAPSEDIWKKFELVPTPPMSPVRILEGSGPSPGDRLEWVSQFLGQDDEQEGLCKLNAEETLENLSSIIIQDCMWSSFSASQQLEKVVSERLSCSAQSKLSGKAQCVPADVPALNSLATDCVDPAAVLTFPLSSSCKKQVSSGSESRTDSSDDEEIDVVTVEHKQNKSRLVNARKPVTITVRADPHDPCMKRFHISIHQQQHNYAARSPDSYPEEEPPRKKIRQEIVQPRLASTPQTPERKSPLPSPSVPAQSPTVSASPTHTSYHLKSQPSSPQSSDCEDTDKRKTHNFLERKRRNDLRSRFLALRDEIPGLVDCPKTPKVVILTKATEYLRTLHVSDRQKAQEKKQLKSKQQQLLRRLAELKRA", "length": 404 }, "evidence": [ { "id": "F1NXY9", "url": "https://omabrowser.org/oma/group/F1NXY9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "F1NXY9", "url": "https://www.uniprot.org/uniprotkb/F1NXY9" } ], "pmid": "" }, { "name": "chromosome", "id": "GO:0005694", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005694", "evidence": [ { "database": "UniProtKB", "id": "F1NXY9", "url": "https://www.uniprot.org/uniprotkb/F1NXY9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "F1NXY9", "url": "https://www.uniprot.org/uniprotkb/F1NXY9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "protein dimerization activity", "id": "GO:0046983", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046983", "evidence": [ { "database": "UniProtKB", "id": "F1NXY9", "url": "https://www.uniprot.org/uniprotkb/F1NXY9" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "F1NXY9", "url": "https://www.uniprot.org/uniprotkb/F1NXY9" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "F1NXY9", "url": "https://www.uniprot.org/uniprotkb/F1NXY9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 80, "end_pos": 82, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1NXY9-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 347, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1NXY9-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1NXY9" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 80, "end_pos": 82 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1NY10-1", "uniprot_ac": "F1NY10", "uniprot_id": "F1NY10_CHICK", "mass": { "chemical_mass": 72186.0, "monoisotopic_mass": 72186.0 }, "refseq": {}, "gene_names": [ { "name": "MED17", "type": "recommended", "evidence": [ { "id": "F1NY10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NY10" } ] } ], "protein_names": [ { "name": "Mediator of RNA polymerase II transcription subunit 17", "type": "recommended", "evidence": [ { "id": "F1NY10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NY10/entry#names_and_taxonomy" } ] }, { "name": "Mediator complex subunit 17", "type": "synonym", "evidence": [ { "id": "F1NY10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NY10/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.", "evidence": [ { "database": "UniProtKB", "id": "F1NY10", "url": "https://www.uniprot.org/uniprotkb/F1NY10#function" }, { "database": "UniProtKB", "id": "ARBA00025687", "url": "https://www.uniprot.org/uniprotkb/ARBA00025687#function" }, { "database": "UniProtKB", "id": "RU364140", "url": "https://www.uniprot.org/uniprotkb/RU364140#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NY10", "url": "https://www.uniprot.org/uniprotkb/F1NY10" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MED17", "url": "https://www.uniprot.org/uniprotkb/F1NY10", "locus": { "chromosome": "1", "start_pos": 185665533, "end_pos": 185679690, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010008775", "url": "https://www.ensembl.org/id/ENSGALG00010008775" } ] } } ], "crossref": [ { "id": "F1NY10", "url": "https://alphafold.ebi.ac.uk/entry/F1NY10", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000017218", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000017218", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "419000", "url": "https://www.ncbi.nlm.nih.gov/gene/419000", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR019313", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019313", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:419000", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419000", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HMSYEPQ", "url": "https://omabrowser.org/oma/group/HMSYEPQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1NY10", "url": "https://www.orthodb.org/?gene=F1NY10", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13114", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13114", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13114:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13114:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10156", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10156", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-9841922", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9841922", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001006280", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006280", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1NY10", "url": "https://www.uniprot.org/uniprotkb/F1NY10", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NY10-1", "url": "https://www.uniprot.org/uniprotkb/F1NY10-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAGVPAVRISIESACEKQVQEVGLDGSETYLQPLSMSQNLARLAQRIDFSQGSGSEEDEPGSAGRAWAEPSEAEDEEGLVKFQPSLWPWDSVRNNLRSALTEMCVLYDVLSIVKDKKFMTLDPVVQDPPPPKQNPQFLQLISKKKSLAGAAQILLKGAERLSKSVAENQENKRQRDFNSELLRLRQHWKLRKVGDKILGDLSYRSAGSLFLHHGTFEVIKNTDIDLDKKIPEDYCPLDVQIPSDLEGSAYIKVSIQKQAPDIGDLGTVNLFKRPMPKSKPGTPHWQTKLETAQNVLLCKEIFAQLSREAVQIKSQIPHIVVKNQIISQPFPGLQLSISLCHSSNDKKSQKSASEKQNPEDHLYVLEHNLHQLIRECHKQTLSSVVMPHPASAPFGHKRMRLAGPQAFDKNEISSLQTNEGLLEKIIKQAKHIFLRRRTARTIDSLASRIEDPQIQAHWSNINDVYESSVKVLITSQGYEQICKSIQLQLNIGVEQIRVVHRDGRVITLSHQEQELQDFLLSQMSQHQVHAVQQLAKVMGWHVLSFSNHVGLGPVESIGNASAITVASPNGDYAISVRNGPESGSKVMVQFPRSQCKDLPKGDVLQDNKWNHLRGPFKEVQWNKMEGRNFVYKMELLMAALTPC", "length": 643, "header": "tr|F1NY10-1|F1NY10_CHICK Isoform 1 of Mediator of RNA polymerase II transcription subunit 17 OS=Gallus gallus OX=9031 GN=MED17 PE=3 SV=1 CANONICAL=F1NY10-1" }, "isoforms": [ { "isoform_ac": "F1NY10-1", "url": "https://www.uniprot.org/uniprotkb/F1NY10/entry#F1NY10-1", "sequence": { "sequence": "MAGVPAVRISIESACEKQVQEVGLDGSETYLQPLSMSQNLARLAQRIDFSQGSGSEEDEPGSAGRAWAEPSEAEDEEGLVKFQPSLWPWDSVRNNLRSALTEMCVLYDVLSIVKDKKFMTLDPVVQDPPPPKQNPQFLQLISKKKSLAGAAQILLKGAERLSKSVAENQENKRQRDFNSELLRLRQHWKLRKVGDKILGDLSYRSAGSLFLHHGTFEVIKNTDIDLDKKIPEDYCPLDVQIPSDLEGSAYIKVSIQKQAPDIGDLGTVNLFKRPMPKSKPGTPHWQTKLETAQNVLLCKEIFAQLSREAVQIKSQIPHIVVKNQIISQPFPGLQLSISLCHSSNDKKSQKSASEKQNPEDHLYVLEHNLHQLIRECHKQTLSSVVMPHPASAPFGHKRMRLAGPQAFDKNEISSLQTNEGLLEKIIKQAKHIFLRRRTARTIDSLASRIEDPQIQAHWSNINDVYESSVKVLITSQGYEQICKSIQLQLNIGVEQIRVVHRDGRVITLSHQEQELQDFLLSQMSQHQVHAVQQLAKVMGWHVLSFSNHVGLGPVESIGNASAITVASPNGDYAISVRNGPESGSKVMVQFPRSQCKDLPKGDVLQDNKWNHLRGPFKEVQWNKMEGRNFVYKMELLMAALTPC", "length": 643, "header": "tr|F1NY10-1|F1NY10_CHICK Isoform 1 of Mediator of RNA polymerase II transcription subunit 17 OS=Gallus gallus OX=9031 GN=MED17 PE=3 SV=1 CANONICAL=F1NY10-1" }, "locus": { "chromosome": "1", "start_pos": 185679493, "end_pos": 185666678, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010020829.1", "url": "https://www.ensembl.org/id/ENSGALT00010020829.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010011995.1", "url": "https://www.ensembl.org/id/ENSGALP00010011995.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:419000", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419000", "resource": "KEGG Pathway" }, { "id": "R-GGA-9841922", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9841922", "resource": "Reactome", "description": "MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis" } ], "orthologs": [ { "uniprot_canonical_ac": "D4ABU0-1", "protein_name": "Mediator of RNA polymerase II transcription subunit 17", "gene_name": "Med17", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSGVRAVRISIESACEKQVQEVGLDGTETYLQPLSMSQNLARLAQRIDFSQGSGSEEEEAAGPDGDAPDWAGAGADQDDEEGLVKFQPSLWPWDSVRNNLRSALTEMCVLYDVLSIVRDKKFMTLDPVSQDALPPKQSPQTLQLISKKKSLAGAAQILLKGAERLTKSVTENQENKLQRDFNSELLRLRQHWKLRKVGDKILGDLSYRSAGSLFPHHGTFEVIKNTDIDLDKKIPEDYCPLDVQIPSDLEGSAYIKVSIQKQAPDIGDLGTVNLFKRPLPKSKPGSPHWQTKLEAAQNVLLCKEIFAQLSREAVQIKSQIPHIVVKNQIISQPFPSLQLSISLCHSSDDKKSQKCAPEKPGQEGHLYVLEHNLHLLIREFHKQTLSSIVMPHPASAPFGHKRMRLSGPQAFDKNEINSIQSTEGLLEKIIKQAKHIFLRSRTAATIDSLASRIEDPQIQAHWSNINDVYESSVKVLITSQGYEQICKSIQLQLNIGVEQVRVVHRDGRVITLSHQEQELQDFLLSQMSQHQVHAVQQLAKVMGWQVLSFSNHVGLGPIESIGNASAITVASPSGDYAISVRNGPESGSKIMVQFPRNQCKDLPKSDVLQDSKWSHLRGPFKEVQWNKMEGRNFVYKMELLMSALSPCLL", "length": 649 }, "evidence": [ { "id": "F1NY10", "url": "https://omabrowser.org/oma/group/F1NY10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3HSP6-1", "protein_name": "Mediator of RNA polymerase II transcription subunit 17", "gene_name": "Med17", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSGVRAVRISIESACEKQVQEVGLDGTETYLQPLSMSQNLARLAQRIDFSQGSGSEEDEAAGPDGDAQDWAGAGAEQDDEEGLVKFQPSLWPWDSVRNNLRSALTEMCVLYDVLSIVRDKKFMTLDPVSQDALPPKQSPQTLQLISKKKSLAGAAQILLKGAERLTKSVTENQENKLQRDFNSELLRLRQHWKLRKVGDKILGDLSYRSAGSLFPHHGTFEVIKNTDIDLDKKIPEDYCPLDVQIPSDLEGSAYIKVSIQKQAPDIGDLGTVNLFKRPLPKSKPGSPHWQTKLEAAQNVLLCKEIFAQLSREAVQIKSQIPHIVVKNQIISQPFPSLQLSISLCHSSNDKKSQKCATEKPGPEDHLYVLEHNLHLLIREFHKQTLSSIVMPHPASAPFGHKRMRLSGPQAFDKNEINSIQSTEGLLEKIIKQAKHIFLRSRTAATIDSLASRIEDPQIQAHWSNINDVYESSVKVLITSQGYEQICKSIQLQLNIGVEQVRVVHRDGRVITLSHQEQELQDFLLSQMSQHQVHAVQQLAKVMGWQVLSFSNHVGLGPIESIGNASAITVASPSGDYAISVRNGPESGSKIMVQFPRNQCKDLPKSDVLQDSKWSHLRGPFKEVQWNKMEGRNFVYKMELLMSALSPCLL", "length": 649 }, "evidence": [ { "id": "F1NY10", "url": "https://omabrowser.org/oma/group/F1NY10/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q5BIR6-1", "protein_name": "Mediator of RNA polymerase II transcription subunit 17", "gene_name": "MED17", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSGVRAVRISIESACEKQVQEVGLDGTETYLQPLSMSQNLARLAQRIDFSQGSGSEEEEAAGAEGDAQDWAGAGSSADQDDEEGLVKFQPSLWPWDSVRNNLRSALTEMCVLYDVLSIVRDKKFMTLDPVSQDALPPKQNPQTLQLISKKKSLAGAAQILLKGAERLTKSVTENQENKLQRDFNSELLRLRQHWKLRKVGDKILGDLSYRSAGSLFPHHGTFEVIKNTDIDLDKKIPEDYCPLDVQIPSDLEGSAYIRVSIQKQAPDIGDLGTVNLFKRPLPKSKPGSPHWQTKLEAAQNVLLCKEIFAQLSREAVQIKSQIPHIVVKNQIISQPFPSLQLSISLCHSSNDKKSPKSATEKQSPEDHLYVLEHNLHLLIREFHKQTLSSIMMPHPASAPFGHKRMRLSGPQAFDKNEINSIQSSEGLLEKIIKQAKHIFLRSRTAATIDSLASRIEDPQIQAHWSNINDVYESSVKVLITSQGYEQICKSIQLQLNIGVEQIRVVHRDGRVITLSHEGQELQDFLLSQMSQHQVHAVQQLAKVMGWQVLSFSNHVGLGPVESIGNASAITVASPNGDYAISVRNGPESGSKIMVQFPRNQCKDLPKSDVLQDSKWNHLRGPFKEVQWNKMEGRNFVYKMELLMSALSPCLL", "length": 651 }, "evidence": [ { "id": "F1NY10", "url": "https://omabrowser.org/oma/group/F1NY10/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q8VCD5-1", "protein_name": "Mediator of RNA polymerase II transcription subunit 17", "gene_name": "Med17", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSGVRAVRISIESACEKQVQEVGLDGTETYLQPLSMSQNLARLAQRIDFSQGSGSEEEEAAGPDGDAPDWGGAGADQDDEEGLVKFQPSLWPWDSVRNNLRSALTEMCVLYDVLSIVRDKKFMTLDPVSQDALPPKQSPQTLQLISKKKSLAGAAQILLKGAERLTKSVAENQENKLQRDFNSELLRLRQHWKLRKVGDKILGDLSYRSAGSLFPHHGTFEVIKNTDIDLDKKIPEDYCPLDVQIPSDLEGSAYIKVSIQKQAPDIGDLGTVNLFKRPLPKSKPGSPHWQTKLEAAQNVLLCKEIFAQLSREAVQIKSQIPHIVVKNQIISQPFPSLQLSISLCHSSDDKKSQKCAAEKPGQEDHLYVLEHNLHLLIREFHKQTLSSIVMPHPASAPFGHKRMRLSGPQAFDKNEINSIQSTEGLLEKIIKQAKHIFLRSRTAATIDSLASRIEDPQIQAHWSNINDVYESSVKVLITSQGYEQICKSIQLQLNIGVEQVRVVHRDGRVIMLSHQEQELQDFLLSQMSQHQVHAVQQLAKVMGWQVLSFSNHVGLGPIESIGNASAITVASPSGDYAISVRNGPESGSKIMVQFPRNQCKDLPKSDVLQDSKWSHLRGPFKEVQWNKMEGRNFVYKMELLMSALSPCLL", "length": 649 }, "evidence": [ { "id": "F1NY10", "url": "https://omabrowser.org/oma/group/F1NY10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9NVC6-1", "protein_name": "Mediator of RNA polymerase II transcription subunit 17", "gene_name": "MED17", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSGVRAVRISIESACEKQVHEVGLDGTETYLPPLSMSQNLARLAQRIDFSQGSGSEEEEAAGTEGDAQEWPGAGSSADQDDEEGVVKFQPSLWPWDSVRNNLRSALTEMCVLYDVLSIVRDKKFMTLDPVSQDALPPKQNPQTLQLISKKKSLAGAAQILLKGAERLTKSVTENQENKLQRDFNSELLRLRQHWKLRKVGDKILGDLSYRSAGSLFPHHGTFEVIKNTDLDLDKKIPEDYCPLDVQIPSDLEGSAYIKVSIQKQAPDIGDLGTVNLFKRPLPKSKPGSPHWQTKLEAAQNVLLCKEIFAQLSREAVQIKSQVPHIVVKNQIISQPFPSLQLSISLCHSSNDKKSQKFATEKQCPEDHLYVLEHNLHLLIREFHKQTLSSIMMPHPASAPFGHKRMRLSGPQAFDKNEINSLQSSEGLLEKIIKQAKHIFLRSRAAATIDSLASRIEDPQIQAHWSNINDVYESSVKVLITSQGYEQICKSIQLQLNIGVEQIRVVHRDGRVITLSYQEQELQDFLLSQMSQHQVHAVQQLAKVMGWQVLSFSNHVGLGPIESIGNASAITVASPSGDYAISVRNGPESGSKIMVQFPRNQCKDLPKSDVLQDNKWSHLRGPFKEVQWNKMEGRNFVYKMELLMSALSPCLL", "length": 651 }, "evidence": [ { "id": "F1NY10", "url": "https://omabrowser.org/oma/group/F1NY10/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VEC1-1", "protein_name": "Mediator of RNA polymerase II transcription subunit 17", "gene_name": "MED17", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSNSVNISVETTCENQIREIGYDGTELYQPPPTLSESLAKCAARIDFSKTSLDDLKKEEKSAAAAADEDKDATQFQESLWPWDAVRNKLKDALTEICVLSDVISIAKDKRYLVLDPLLEEADDTKPIVQVYSRKKAISQAAQVLLSGAERLRNAHSEQRNRNVSDFHIELLRLRQNWRLKKVSNAIIGDLSYRTAGSKFGMSGTFEVTKAEETGDEDTASSSNSSSSVSGNNGMQLKASSALRVIVPAELQGVAYIKVITQKDQEDLCTAQLNLMGHGPNITAQVGVWQKTLEFAQNVLFCKELFAQLAREAIQLQAPIPHVVIGNQIRATLLPNIQLIISLCHSTTFDSSQPAPINDHDHVLEHSLHQLLREVHYKNSHHPFPHPASAPLGPTKKRMLAGPMAADRETLLDMTKSQTILEQIIAQAQHIFMRKRTQYVLDTLARDVKDPQIVSHWNAMNSPTMSCVKINIVTHGYDAIGRTSLVIHVKERSLKCICRDGRVMRLSYEPQELRDLILCQINSHQISCLISLARCMSWTVLSNSNHLGIGKVEPLGNASSCLLASPNSDRMIAVQIRCDPQIDVKVYIARSPRQDFFPSPLVPEKLWENLGGTFKEVRFDKIEGKSFLNKMEFLMASLTSNTA", "length": 642 }, "evidence": [ { "id": "F1NY10", "url": "https://omabrowser.org/oma/group/F1NY10/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "positive regulation of transcription initiation by RNA polymerase II", "id": "GO:0060261", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060261", "evidence": [ { "database": "UniProtKB", "id": "F1NY10", "url": "https://www.uniprot.org/uniprotkb/F1NY10" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "F1NY10", "url": "https://www.uniprot.org/uniprotkb/F1NY10" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "F1NY10", "url": "https://www.uniprot.org/uniprotkb/F1NY10" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "transcription coactivator activity", "id": "GO:0003713", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003713", "evidence": [ { "database": "UniProtKB", "id": "F1NY10", "url": "https://www.uniprot.org/uniprotkb/F1NY10" } ], "pmid": "" }, { "name": "nuclear thyroid hormone receptor binding", "id": "GO:0046966", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046966", "evidence": [ { "database": "UniProtKB", "id": "F1NY10", "url": "https://www.uniprot.org/uniprotkb/F1NY10" } ], "pmid": "" }, { "name": "transcription coregulator activity", "id": "GO:0003712", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003712", "evidence": [ { "database": "UniProtKB", "id": "F1NY10", "url": "https://www.uniprot.org/uniprotkb/F1NY10" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "mediator complex", "id": "GO:0016592", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016592", "evidence": [ { "database": "UniProtKB", "id": "F1NY10", "url": "https://www.uniprot.org/uniprotkb/F1NY10" } ], "pmid": "" }, { "name": "core mediator complex", "id": "GO:0070847", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070847", "evidence": [ { "database": "UniProtKB", "id": "F1NY10", "url": "https://www.uniprot.org/uniprotkb/F1NY10" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 559, "end_pos": 561, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1NY10-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 643, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1NY10-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1NY10" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 559, "end_pos": 561 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": 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"MNLKAFIFLLPNFIFGMFLFGFFCRRQKDLMVADSFRGPTEDWLTIQNDRRNTLASICQKNNLIKLKSKLDSHVASQIFVEHKHKFTYCEVPKVGCSNWKRTILILQEGLNVEASEIEHDHIHQTSMIKRLSAYPPAIQEEFLNNYTKVMFTRHPLERLVSAYRDKLLHFEPYYSTTVANKIKAMFRKNKNSSEKVSFQEFVSFITVNPPNTLDIHWKPMFLLCDPCNIHYDILGKYETLGLDSAQVLKAIGAPESLQYPSLKRYGSEKRTNDDITLEYLRQLSSEQIEKIKKLYQMDFLLFNYTLKYENYFSLKH", "length": 316, "header": "tr|F1NY83-1|F1NY83_CHICK Isoform 1 of Carbohydrate sulfotransferase OS=Gallus gallus OX=9031 GN=LOC101747844 PE=3 SV=3 CANONICAL=F1NY83-1" }, "locus": { "chromosome": "5", "start_pos": 24176749, "end_pos": 24175378, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054836.1", "url": "https://www.ensembl.org/id/ENSGALT00010054836.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033145.1", "url": "https://www.ensembl.org/id/ENSGALP00010033145.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "gga:101747844", "name": 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"pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "F1NY83", "url": "https://www.uniprot.org/uniprotkb/F1NY83" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 145, "end_pos": 147, "annotation": "n_glycosylation_sequon" }, { "start_pos": 191, "end_pos": 193, "annotation": "n_glycosylation_sequon" }, { "start_pos": 303, "end_pos": 305, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1NY83-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 316, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1NY83-F1.pdb", "url_external": 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{ "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1NYN5-1", "uniprot_ac": "F1NYN5", "uniprot_id": "F1NYN5_CHICK", "mass": { "chemical_mass": 54609.0, "monoisotopic_mass": 54609.0 }, "refseq": { "ac": "NP_001186532", "name": "sodium-coupled neutral amino acid symporter 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186532" }, "gene_names": [ { "name": "SLC38A1", "type": "recommended", "evidence": [ { "id": "F1NYN5", "database": "UniProtKB", "url": 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RNAseq introns :: mixed sample support SAMEA103992290, SAMEA103992323 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000012.1. On or before Dec 6, 2021 this sequence version replaced XP_015136794.1, XP_416048.2.", "evidence": [ { "database": "RefSeq", "id": "NP_001186532", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186532" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NYN5", "url": "https://www.uniprot.org/uniprotkb/F1NYN5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SLC38A1", "url": "https://www.uniprot.org/uniprotkb/F1NYN5", "locus": { "chromosome": "1", "start_pos": 31073821, "end_pos": 31110913, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013964", "url": "https://www.ensembl.org/id/ENSGALG00010013964" } ] } } ], "crossref": [ { "id": "F1NYN5", "url": "https://alphafold.ebi.ac.uk/entry/F1NYN5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000009698", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000009698", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "417806", "url": "https://www.ncbi.nlm.nih.gov/gene/417806", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013057", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013057", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:417806", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417806", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CSAMAIY", "url": "https://omabrowser.org/oma/group/CSAMAIY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1NYN5", "url": "https://www.orthodb.org/?gene=F1NYN5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22950", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22950", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22950:SF184", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22950:SF184", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01490", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01490", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-210455", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-210455", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-352230", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-352230", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001186532", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186532", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1NYN5", "url": "https://www.uniprot.org/uniprotkb/F1NYN5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NYN5-1", "url": 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"MPFKAGLELTELQNMTIPEDDNISNDSNDFTEVENGQINSKFISDRESRRSLTNSHLEKKKCDEYIPGTTSLGMSVFNLSNAIMGSGILGLAFALANTGIVLFSLLLVSVTLLSIYSIHLLLVCSKETGCMVYEKLGEQVFGTPGKMIVFGSTSLQNIGAMLSYLFIVKNELPSAIKFLMGKEETFSAWYVDGRILVVAVTFIIILPLCLLKNLGYLGYTSGFSLSCMVFFLIVVIYKKFQILCLESALNATSPILSNSSAHEHMCKPKYVIFNSKTVYALPTIAFAFVCHPSVLPIYSELKDRSQKKMQLVSNISFFAMFVMYFLTAIFGYLTFYENVQSDLLHKYQSKDDILILTVRLAVIVAVILTVPVLFFTVRSSLFELARKTKFDIGRHVLVTFFLLVIINLLVIFIPTMKDIFGVVGVTSANMLIFILPSSLYLKITHQDGAKFTQRIWASLFLVLGIMFSLVSIPLVIYDWVQSGGSTEGSD", "length": 490, "header": "tr|F1NYN5-1|F1NYN5_CHICK Isoform 1 of Solute carrier family 38 member 1 OS=Gallus gallus OX=9031 GN=SLC38A1 PE=4 SV=2 CANONICAL=F1NYN5-1" }, "locus": { "chromosome": "1", "start_pos": 31102856, "end_pos": 31078604, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033496.1", "url": "https://www.ensembl.org/id/ENSGALT00010033496.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019754.1", "url": "https://www.ensembl.org/id/ENSGALP00010019754.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:417806", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417806", "resource": "KEGG Pathway" }, { "id": "R-GGA-210455", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-210455", "resource": "Reactome", "description": "Astrocytic Glutamate-Glutamine Uptake And Metabolism" }, { "id": "R-GGA-352230", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-352230", "resource": "Reactome", "description": "Amino acid transport across the plasma membrane" } ], "orthologs": [ { "uniprot_canonical_ac": "F1MTX9-1", "protein_name": "Solute carrier family 38 member 1", "gene_name": "SLC38A1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MMHFKSGLELTELQNMTVPEDDNISNDSNDFTEVENGQINSKFISDRESRRSLTNSHLEKKKCDDYIPGTTSLGMSVFNLSNAIMGSGILGLAFALANTGILLFLVLLTSVTLLSIYSINLLLICSKETGCMVYEKLGEQVFGTTGKLVIFGATSLQNTGAMLSYLFIVKNELPSAIKFLMGKEEEFSAWYVDGRLLVVVVTFGIILPLCLLKNLGYLGYTSGFSLSCMVFFLIVVIYKKFKITCSVPELNSTIPNSTNPDMCTPKYVTFNSKTVYALPTIAFAFVCHPSVLPIYSELKDRSQKKMQMVSNISFFAMFVMYFLTAIFGYLTFYESVQSDLLHKYQSKNDILILTVRLAVIMAVILTVPVLFFTVRSSLFELAKKTKFNLCRHVLVTILLLVIINLLVIFIPSMKDIFGVVGVTSANMLIFILPSSLYLKITSQDGDKGTQQIWAALFLGLGVLFSLVSIPLVIYDWAYSSSGDEGH", "length": 486 }, "evidence": [ { "id": "F1NYN5", "url": "https://omabrowser.org/oma/group/F1NYN5/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q8K2P7-1", "protein_name": "Sodium-coupled neutral amino acid symporter 1", "gene_name": "Slc38a1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MMHFKSGLELTELQNMTVPEDDNVSNDSNDFTEVENGQINSKFISDRESRRSLTNSHLEKRKCDEYIPGTTSLGMSVFNLSNAIMGSGILGLAFALANTGILLFLILLTSVTLLSIYSINLLLICSKETGCMVYEKLGEQVFGTTGKLVIFGATSLQNTGAMLSYLFIVKNELPSAIKSLMGEEDAFSAWYVDGRVLVVMVTFGIILPLCLLKNLGYLGYTSGFSLSCMMFFLIVVIYKKFQTPCMSVEQNSTVSANVTDACTPKYVTFNSKTVYALPTIAFAFVCHPSVLPIYSELKDRSQKKMQMVSNISFFAMFVMYFLTAIFGYLTFYEKVQSDLLHKYQSTGDILILTVRLAVIVAVILTVPVLFFTVRSSLFELAKKTKFHLCRHVLVTIILLIIINLLVIFIPSMKDIFGVVGVTSANMLIFILPSSLYLKITNQDGDKGTQRIWAALFLGLGVLFSLISIPLVIYDWACSSGTDEGH", "length": 485 }, "evidence": [ { "id": "F1NYN5", "url": "https://omabrowser.org/oma/group/F1NYN5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9H2H9-1", "protein_name": "Sodium-coupled neutral amino acid symporter 1", "gene_name": "SLC38A1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MMHFKSGLELTELQNMTVPEDDNISNDSNDFTEVENGQINSKFISDRESRRSLTNSHLEKKKCDEYIPGTTSLGMSVFNLSNAIMGSGILGLAFALANTGILLFLVLLTSVTLLSIYSINLLLICSKETGCMVYEKLGEQVFGTTGKFVIFGATSLQNTGAMLSYLFIVKNELPSAIKFLMGKEETFSAWYVDGRVLVVIVTFGIILPLCLLKNLGYLGYTSGFSLSCMVFFLIVVIYKKFQIPCIVPELNSTISANSTNADTCTPKYVTFNSKTVYALPTIAFAFVCHPSVLPIYSELKDRSQKKMQMVSNISFFAMFVMYFLTAIFGYLTFYDNVQSDLLHKYQSKDDILILTVRLAVIVAVILTVPVLFFTVRSSLFELAKKTKFNLCRHTVVTCILLVVINLLVIFIPSMKDIFGVVGVTSANMLIFILPSSLYLKITDQDGDKGTQRIWAALFLGLGVLFSLVSIPLVIYDWACSSSSDEGH", "length": 487 }, "evidence": [ { "id": "F1NYN5", "url": "https://omabrowser.org/oma/group/F1NYN5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9JM15-1", "protein_name": "Sodium-coupled neutral amino acid symporter 1", "gene_name": "Slc38a1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MMHFKSGLELTELQNMTVPEDDNVSNDSNDFTEVENGQINSKFISDRESRRSLTNSHLEKRKCDEYIPGTTSLGMSVFNLSNAIMGSGILGLAFALANTGILLFLILLTSVTLLSIYSINLLLICSKETGCMVYEKLGEQVFGTTGKLVIFGATSLQNTGAMLSYLFIVKNELPSAIKSLMGEEETFSAWYVDGRVLVVMVTFGIILPLCLLKNLGYLGYTSGFSLSCMVFFLIVVIYKKFQIPCMNGEQNSTVSANVTDACTPKYVTFNSKTVYALPTIAFAFVCHPSVLPIYSELKDRSQKKMQMVSNISFFAMFVMYFLTAIFGYLTFYEKVQSDLLHKYQSTGDILILTVRLAVIVAVILTVPVLFFTVRSSLFELAKKTKFHLCRHVLVTIILLVIINLLVIFIPSMKDIFGVVGVTSANMLIFILPSSLYLKITNQDGDKNTQRIWAALFLALGVLFSLISIPLVIYDWACSSSNGEGH", "length": 485 }, "evidence": [ { "id": "F1NYN5", "url": "https://omabrowser.org/oma/group/F1NYN5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F1NYN5", "url": "https://www.uniprot.org/uniprotkb/F1NYN5" } ], "pmid": "" }, { "name": "basolateral plasma membrane", "id": "GO:0016323", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016323", "evidence": [ { "database": "UniProtKB", "id": "F1NYN5", "url": "https://www.uniprot.org/uniprotkb/F1NYN5" } ], "pmid": "" }, { "name": "axon", "id": "GO:0030424", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030424", "evidence": [ { "database": "UniProtKB", "id": "F1NYN5", "url": "https://www.uniprot.org/uniprotkb/F1NYN5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "regulation of synaptic plasticity", "id": "GO:0048167", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048167", "evidence": [ { "database": "UniProtKB", "id": "F1NYN5", "url": "https://www.uniprot.org/uniprotkb/F1NYN5" } ], "pmid": "" }, { "name": "glutamine transport", "id": "GO:0006868", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006868", "evidence": [ { "database": "UniProtKB", "id": "F1NYN5", "url": "https://www.uniprot.org/uniprotkb/F1NYN5" } ], "pmid": "" }, { "name": "amino acid transmembrane transport", "id": "GO:0003333", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003333", "evidence": [ { "database": "UniProtKB", "id": "F1NYN5", "url": "https://www.uniprot.org/uniprotkb/F1NYN5" } ], "pmid": "" }, { "name": "regulation of synaptic transmission, GABAergic", "id": "GO:0032228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032228", "evidence": [ { "database": "UniProtKB", "id": "F1NYN5", "url": "https://www.uniprot.org/uniprotkb/F1NYN5" } ], "pmid": "" }, { "name": "gamma-aminobutyric acid biosynthetic process", "id": "GO:0009449", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009449", "evidence": [ { "database": "UniProtKB", "id": "F1NYN5", "url": "https://www.uniprot.org/uniprotkb/F1NYN5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "L-glutamine transmembrane transporter activity", "id": "GO:0015186", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015186", "evidence": [ { "database": "UniProtKB", "id": "F1NYN5", "url": "https://www.uniprot.org/uniprotkb/F1NYN5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 14, "end_pos": 16, "annotation": "n_glycosylation_sequon" }, { "start_pos": 22, "end_pos": 24, "annotation": "n_glycosylation_sequon" }, { "start_pos": 250, "end_pos": 252, "annotation": "n_glycosylation_sequon" }, { "start_pos": 258, "end_pos": 260, "annotation": "n_glycosylation_sequon" }, { "start_pos": 25, "end_pos": 27, "annotation": "n_glycosylation_sequon" }, { "start_pos": 314, "end_pos": 316, "annotation": "n_glycosylation_sequon" }, { "start_pos": 78, "end_pos": 80, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1NYN5-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 490, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1NYN5-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1NYN5" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1NYN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NYN5" }, { "id": "PF01490", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01490" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Amino acid transporter transmembrane", "eco_id": "ECO_0000259", "start_pos": 69, "end_pos": 474, "start_aa": "Thr", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 14, "end_pos": 16 }, { "start_pos": 22, "end_pos": 24 }, { "start_pos": 250, "end_pos": 252 }, { "start_pos": 258, "end_pos": 260 }, { "start_pos": 25, "end_pos": 27 }, { "start_pos": 314, "end_pos": 316 }, { "start_pos": 78, "end_pos": 80 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1NZ19-1", "uniprot_ac": "F1NZ19", "uniprot_id": "F1NZ19_CHICK", "mass": { "chemical_mass": 33525.0, "monoisotopic_mass": 33525.0 }, "refseq": { "ac": "XP_421386", "name": "tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRMT61A", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_421386" }, "gene_names": [ { "name": "TRMT61A", "type": "recommended", "evidence": [ { "id": "F1NZ19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NZ19" } ] }, { "name": "TRMT61A", "type": "synonym", "evidence": [ { "id": "XP_421386", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_421386" } ] } ], "protein_names": [ { "name": "tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRMT61A", "type": "recommended", "evidence": [ { "id": "F1NZ19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NZ19/entry#names_and_taxonomy" } ] }, { "name": "2.1.1.220", "type": "synonym", "evidence": [ { "id": "F1NZ19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NZ19/entry#names_and_taxonomy" } ] }, { "name": "tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRMT61A", "type": "synonym", "evidence": [ { "id": "XP_421386", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_421386" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052536.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 19, 2013 this sequence version replaced XP_421386.3. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_421386", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_421386" } ] }, { "annotation": "Catalytic subunit of tRNA (adenine-N(1)-)-methyltransferase, which catalyzes the formation of N(1)-methyladenine at position 58 (m1A58) in initiator methionyl-tRNA. Catalytic subunit of mRNA N(1)-methyltransferase complex, which mediates methylation of adenosine residues at the N(1) position of a small subset of mRNAs: N(1) methylation takes place in tRNA T-loop-like structures of mRNAs and is only present at low stoichiometries.", "evidence": [ { "database": "UniProtKB", "id": "F1NZ19", "url": "https://www.uniprot.org/uniprotkb/F1NZ19#function" }, { "database": "UniProtKB", "id": "ARBA00056495", "url": "https://www.uniprot.org/uniprotkb/ARBA00056495#function" }, { "database": "UniProtKB", "id": "A0A8V0YVI6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YVI6#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NZ19", "url": "https://www.uniprot.org/uniprotkb/F1NZ19" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TRMT61A", "url": "https://www.uniprot.org/uniprotkb/F1NZ19", "locus": { "chromosome": "5", "start_pos": 49887125, "end_pos": 49840026, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010015879", "url": "https://www.ensembl.org/id/ENSGALG00010015879" } ] } } ], "crossref": [ { "id": "F1NZ19", "url": "https://alphafold.ebi.ac.uk/entry/F1NZ19", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000011522", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000011522", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "423481", "url": "https://www.ncbi.nlm.nih.gov/gene/423481", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR014816", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014816", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029063", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029063", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR049470", "url": "https://www.ebi.ac.uk/interpro/entry/IPR049470", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:423481", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423481", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "RPDHRMI", "url": "https://omabrowser.org/oma/group/RPDHRMI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1NZ19", "url": "https://www.orthodb.org/?gene=F1NZ19", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12133", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12133", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12133:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12133:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF08704", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08704", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_421386", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_421386", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "43152", "url": "https://www.rhea-db.org/rhea/43152", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "55392", "url": "https://www.rhea-db.org/rhea/55392", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YVI6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YVI6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YVI6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YVI6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NZ19", "url": "https://www.uniprot.org/uniprotkb/F1NZ19", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NZ19-1", "url": "https://www.uniprot.org/uniprotkb/F1NZ19-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSFVEYGDTIKDGDTAIVFLGHESMFPVKVQHGGVTQTKYGVIRHSTDLIGKKYGSKVTCSKGGWVFILHPTPELWTVNLPHRTQILYSTDISVITMMLELKPGSIVCESGTGSGSLSHALIRTVAPTGHLYTVEFHQQRAEKAKEEFREHGVEHLVTVTNQDVCKNGFGVSGIADAVFLDIPSPWEAIGHAKSALKAEGGRICSFSPCIEQVQRTCLAMEEYGFTEINTLEILLRVYNVRTISLQIPDLGKAAEDNSSAGFDSSNPSNQGSPGTNLQQGTVQFKSGVPLKEMVGHTGYLTFATKSLF", "length": 308, "header": "tr|F1NZ19-1|F1NZ19_CHICK Isoform 1 of tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRMT61A OS=Gallus gallus OX=9031 GN=TRMT61A PE=1 SV=2 CANONICAL=F1NZ19-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YVI6-1", "url": "https://www.uniprot.org/uniprotkb/F1NZ19/entry#A0A8V0YVI6-1", "sequence": { "sequence": "MSFVEYGDTIKDGDTAIVFLGHESMFPVKVQHGGVTQTKYGVIRHSTDLIGKKYGSKVTCSKGGWVFILHPTPELWTVNLPHRTQILYSTDISVITMMLELKPGSIVCESGTGSGSLSHALIRTVAPTGHLYTVEFHQQRAEKAKEEFREHGVEHLVTVTNQDVCKNGFGVSGIADAVFLDIPSPWEAIGHAKSALKAEGGRICSFSPCIEQVQRTCLAMEEYGFTEINTLEILLRVYNVRTISLQIPDLGKAAEDNSSAGFDSSNPSNQGSPGTNLQQGTVQFKSGVPLKEMVLWAT", "length": 298, "header": "tr|A0A8V0YVI6-1|A0A8V0YVI6_CHICK Computationally mapped isoform of tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRMT61A OS=Gallus gallus OX=9031 GN=TRMT61A PE=1 SV=1 CANONICAL=F1NZ19-1" }, "locus": { "chromosome": "5", "start_pos": 49862295, "end_pos": 49842083, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010038268.1", "url": "https://www.ensembl.org/id/ENSGALT00010038268.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010022091.1", "url": "https://www.ensembl.org/id/ENSGALP00010022091.1" } ] } }, { "isoform_ac": "F1NZ19-1", "url": "https://www.uniprot.org/uniprotkb/F1NZ19/entry#F1NZ19-1", "sequence": { "sequence": "MSFVEYGDTIKDGDTAIVFLGHESMFPVKVQHGGVTQTKYGVIRHSTDLIGKKYGSKVTCSKGGWVFILHPTPELWTVNLPHRTQILYSTDISVITMMLELKPGSIVCESGTGSGSLSHALIRTVAPTGHLYTVEFHQQRAEKAKEEFREHGVEHLVTVTNQDVCKNGFGVSGIADAVFLDIPSPWEAIGHAKSALKAEGGRICSFSPCIEQVQRTCLAMEEYGFTEINTLEILLRVYNVRTISLQIPDLGKAAEDNSSAGFDSSNPSNQGSPGTNLQQGTVQFKSGVPLKEMVGHTGYLTFATKSLF", "length": 308, "header": "tr|F1NZ19-1|F1NZ19_CHICK Isoform 1 of tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRMT61A OS=Gallus gallus OX=9031 GN=TRMT61A PE=1 SV=2 CANONICAL=F1NZ19-1" }, "locus": { "chromosome": "5", "start_pos": 49859512, "end_pos": 49842083, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010038272.1", "url": "https://www.ensembl.org/id/ENSGALT00010038272.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010022095.1", "url": "https://www.ensembl.org/id/ENSGALP00010022095.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "gga:423481", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423481", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287BGP5-1", "protein_name": "tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRMT61A", "gene_name": "TRMT61A", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSFVAYEELIKEGDTAILSLGHGAMVAVRVQRGAQTQTRHGVLRHSVDLIGRPFGSKVTCGRGGWVYVLHPTPELWTLNLPHRTQILYSTDIALLTMMLELRPGSVVCESGTGSGSVSHAIIRTIAPTGHLHTVEFHQQRAEKAREEFQEHRVGRWVTVRNQDVCRSGFGVSHVADAVFLDIPSPWEAVGHAWDALKVEGGRFCSFSPCIEQVQRTCQALVARGFSELSTLEVLPQVYHVRTVSLPAPDLGASPGPDARPFRSGTPMKEAVGHTGYLTFATKTLG", "length": 285 }, "evidence": [ { "id": "F1NZ19", "url": "https://omabrowser.org/oma/group/F1NZ19/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3H378-1", "protein_name": "tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRMT61A", "gene_name": "Trmt61a", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSFVAYEELIKEGDTAILSLGHGSMMAVRVQRGAQTQTRHGVLRHSVDLIGRPFGSKVICSRGGWVYVLHPTPELWTVNLPHRTQILYSTDIALITMMLELRPGSVVCESGTGSGSVSHAIIRSIAPTGHLHTVEFHQQRADKAREEFQEHRVSQWVTVHTQDVCRSGFGVTHVADAVFLDIPSPWETVGHAWDALKVEGGRFCSFSPCIEQVQRTCQALAAHGFTELSTLEVLPQVYNVRTVSLPLPDLGASDLEVSMGSDASPFRSGTPMKETVGHTGYLTFATKTPG", "length": 290 }, "evidence": [ { "id": "F1NZ19", "url": "https://omabrowser.org/oma/group/F1NZ19/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P46959-1", "protein_name": "tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRM61", "gene_name": "GCD14", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSTNCFSGYKDLIKEGDLTLIWVSRDNIKPVRMHSEEVFNTRYGSFPHKDIIGKPYGSQIAIRTKGSNKFAFVHVLQPTPELWTLSLPHRTQIVYTPDSSYIMQRLNCSPHSRVIEAGTGSGSFSHAFARSVGHLFSFEFHHIRYEQALEEFKEHGLIDDNVTITHRDVCQGGFLIKKGDTTSYEFGNNETAASLNANVVFLDLPAPWDAIPHLDSVISVDEKVGLCCFSPCIEQVDKTLDVLEKYGWTDVEMVEIQGRQYESRRQMVRSLNDALERLRDIKRHKLQGVERRKRMFNNTIDSNDEKVGKRNEDGVPLTEKAKFNPFGKGSRIKEGDSNYKWKEVTKMEAEIKSHTSYLTFAFKVVNRSRDDEKVNEILRSTEK", "length": 383 }, "evidence": [ { "id": "F1NZ19", "url": "https://omabrowser.org/oma/group/F1NZ19/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q6AY46-1", "protein_name": "tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRMT61A", "gene_name": "Trmt61a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSFVAYEELIKEGDTAILSLGHGSMVAVRVQRGAQTQTRHGVLRHSVDLIGRPFGSKVTCSRGGWVYVLHPTPELWTVNLPHRTQILYSTDIALITMMLELRPGSVVCESGTGSGSVSHAIIRSIAPTGHLHTVEFHQQRADKAREEFQQHRVSQWVTVHTQDVCRSGFGVVHVADAVFLDIPSPWEAVGHAWDALKVEGGRFCSFSPCIEQVQRTCQALAAHGFTELSTLEVLPQVYNVRTVSLPLPDLGADDLEGNVGSDATPFRSGTPMKETVGHTGYLTFATKTPG", "length": 290 }, "evidence": [ { "id": "F1NZ19", "url": "https://omabrowser.org/oma/group/F1NZ19/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q80XC2-1", "protein_name": "tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRMT61A", "gene_name": "Trmt61a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSFVAYEELIKEGDTAILSLGHGSMVAVRVQRGAQTQTRHGVLRHSVDLIGRPFGSKVICSRGGWVYVLHPTPELWTVNLPHRTQILYSTDIALITMMLELRPGSVVCESGTGSGSVSHAIIRSVAPTGHLHTVEFHQQRADKAREEFQEHRLSQWVTVHTQDVCCSGFGVVHVADAVFLDIPSPWEAVGHAWDALKVEGGRFCSFSPCIEQVQRTCQALAAHGFTELSTLEVLPQVYNVRTVSLPLPDLGANNLETNMGSDASPFRSGTPMKETVGHTGYLTFATKTPG", "length": 290 }, "evidence": [ { "id": "F1NZ19", "url": "https://omabrowser.org/oma/group/F1NZ19/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q86JJ0-1", "protein_name": "tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit trmt61a", "gene_name": "trmt61a", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MLNPNKIIKEGDRVVMYNGKDNMAVLTMESNNVYNSKFGSYRHKNIIGKEYGSKLSSDNGNGFCHVIAMTPELWSITLDHRTQILFNLDISTIIFNLELKNGSRAVESGTGSGSLSSSIARTIAPKGHLFTFEFHEERVKFARKDFKDNGLDQYITVTHRDACGKEGFLRQDINNDIDAVFLDLPSPWDAIENAIAVMHDGSMLCSFSPCIEQVQNTCLKLADSKFQEIKTIEVLIRTFDTRLQEYEELNLTNPYIDNNNNNNNNNNIEENRGKFEIGGIEGLKKDKLLSKPFTEARGHTGYLTFARYLPNA", "length": 312 }, "evidence": [ { "id": "F1NZ19", "url": "https://omabrowser.org/oma/group/F1NZ19/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q96FX7-1", "protein_name": "tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRMT61A", "gene_name": "TRMT61A", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSFVAYEELIKEGDTAILSLGHGAMVAVRVQRGAQTQTRHGVLRHSVDLIGRPFGSKVTCGRGGWVYVLHPTPELWTLNLPHRTQILYSTDIALITMMLELRPGSVVCESGTGSGSVSHAIIRTIAPTGHLHTVEFHQQRAEKAREEFQEHRVGRWVTVRTQDVCRSGFGVSHVADAVFLDIPSPWEAVGHAWDALKVEGGRFCSFSPCIEQVQRTCQALAARGFSELSTLEVLPQVYNVRTVSLPPPDLGTGTDGPAGSDTSPFRSGTPMKEAVGHTGYLTFATKTPG", "length": 289 }, "evidence": [ { "id": "F1NZ19", "url": "https://omabrowser.org/oma/group/F1NZ19/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VBH7-1", "protein_name": "tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRMT61A", "gene_name": "Trmt61", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSFLKPKTHIEKGDVVILYLSVSSMHAIEAVPEIVNKKGETIPHIFQTNYGSLKVENIIGVEYGSKVELSKGWAHVLQPTPELWTQTLPHRTQIIYTPDISMIIHQLEVRPGAVVVESGTGSGSLSHYFLRALKPTGHLHTFDFHEARADQARDEFRRHGIADFVTVYHRDVCNLGFGAELDGKADAVFLDLPAPDLAVPHAFKALKLSGGRFCSFSPCIEQSQRCIQELTKLGFNEIVSLEVLQQENVVKTRTLPVIDLEFLKLPKTDETTAATNALESKAPKEVKKYLTSSNPQTLPGHTGFLTFATLPPNIPKA", "length": 317 }, "evidence": [ { "id": "F1NZ19", "url": "https://omabrowser.org/oma/group/F1NZ19/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1NZ19", "url": "https://www.uniprot.org/uniprotkb/F1NZ19" } ], "pmid": "" }, { "name": "tRNA (m1A) methyltransferase complex", "id": "GO:0031515", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031515", "evidence": [ { "database": "UniProtKB", "id": "F1NZ19", "url": "https://www.uniprot.org/uniprotkb/F1NZ19" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "mRNA processing", "id": "GO:0006397", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006397", "evidence": [ { "database": "UniProtKB", "id": "F1NZ19", "url": "https://www.uniprot.org/uniprotkb/F1NZ19" } ], "pmid": "" }, { "name": "tRNA methylation", "id": "GO:0030488", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030488", "evidence": [ { "database": "UniProtKB", "id": "F1NZ19", "url": "https://www.uniprot.org/uniprotkb/F1NZ19" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "mRNA (adenine-N1-)-methyltransferase activity", "id": "GO:0061953", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061953", "evidence": [ { "database": "UniProtKB", "id": "F1NZ19", "url": "https://www.uniprot.org/uniprotkb/F1NZ19" } ], "pmid": "" }, { "name": "tRNA (adenine(58)-N1)-methyltransferase activity", "id": "GO:0160107", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160107", "evidence": [ { "database": "UniProtKB", "id": "F1NZ19", "url": "https://www.uniprot.org/uniprotkb/F1NZ19" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 257, "end_pos": 259, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "43152", "name": "", "equation": "adenosine(58) in tRNA + S-adenosyl-L-methionine = N(1)-methyladenosine(58) in tRNA + S-adenosyl-L-homocysteine + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1NZ19-1" ], "evidence": [ { "id": "43152", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/43152" } ] }, { "id": "55392", "name": "", "equation": "an adenosine in mRNA + S-adenosyl-L-methionine = an N(1)-methyladenosine in mRNA + S-adenosyl-L-homocysteine + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1NMQ4-1", "F1NZ19-1", "A0A8V0Z9V7-1" ], "evidence": [ { "id": "55392", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/55392" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A8V0Z9V7", "gene_name": "TRMT61B", "activity": [ { "ec_number": "2.1.1.220", "activity": "adenosine(58) in tRNA + S-adenosyl-L-methionine = N(1)-methyladenosine(58) in tRNA + S-adenosyl-L-homocysteine + H(+).", "evidence": [ { "id": "A0A8V0Z9V7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9V7" } ] }, { "ec_number": "2.1.1.220", "activity": "", "evidence": [ { "id": "A0A8V0Z9V7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9V7" } ] } ] }, { "uniprot_ac": "F1NMQ4", "gene_name": "TRMT10C", "activity": [ { "ec_number": "2.1.1.218", "activity": "adenosine(9) in tRNA + S-adenosyl-L-methionine = N(1)-methyladenosine(9) in tRNA + S-adenosyl-L-homocysteine + H(+).", "evidence": [ { "id": "F1NMQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NMQ4" } ] }, { "ec_number": "2.1.1.221", "activity": "guanosine(9) in tRNA + S-adenosyl-L-methionine = N(1)-methylguanosine(9) in tRNA + S-adenosyl-L-homocysteine + H(+).", "evidence": [ { "id": "F1NMQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NMQ4" } ] }, { "ec_number": "2.1.1.221", "activity": "", "evidence": [ { "id": "F1NMQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NMQ4" } ] }, { "ec_number": "2.1.1.218", "activity": "", "evidence": [ { "id": "F1NMQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NMQ4" } ] } ] }, { "uniprot_ac": "F1NZ19", "gene_name": "TRMT61A", "activity": [ { "ec_number": "2.1.1.220", "activity": "adenosine(58) in tRNA + S-adenosyl-L-methionine = N(1)-methyladenosine(58) in tRNA + S-adenosyl-L-homocysteine + H(+).", "evidence": [ { "id": "F1NZ19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NZ19" } ] }, { "ec_number": "2.1.1.220", "activity": "", "evidence": [ { "id": "F1NZ19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NZ19" } ] } ] } ], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1NZ19-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 308, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1NZ19-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1NZ19" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1NZ19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NZ19" }, { "id": "PF08704", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08704" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRM61 C-terminal", "eco_id": "ECO_0000259", "start_pos": 64, "end_pos": 305, "start_aa": "Gly", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.1.1.220", "ec_name": "adenosine(58) in tRNA + S-adenosyl-L-methionine = N(1)-methyladenosine(58) in tRNA + S-adenosyl-L-homocysteine + H(+).", "evidence": [ { "id": "2.1.1.220", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.220" }, { "id": "2.1.1.220", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.1.1.220" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 257, "end_pos": 259 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { 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"MDTFSTKNLALQAQKKLLSKMASKTVANVFIDDTSSEILDELYRATKEYTHNRKEAQKIIKNLIKIVMKLGVLYRNGQFSPEELLVMERFRKKVHTLAMTAVSFHQIDFTFDRRVMSSVLTECRDLLHQAVSSHLTAKSHSRINHVFNHFADYEFLSALYGPAEPYRTHLKRICEGVNKMLEEDNI", "length": 186, "header": "tr|F1NZ26-1|F1NZ26_CHICK Isoform 1 of Tumor necrosis factor alpha-induced protein 8-like protein 1 OS=Gallus gallus OX=9031 GN=TNFAIP8L1 PE=3 SV=1 CANONICAL=F1NZ26-1" }, "locus": { "chromosome": "28", "start_pos": 5388546, "end_pos": 5387989, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068388.1", "url": "https://www.ensembl.org/id/ENSGALT00010068388.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042113.1", "url": "https://www.ensembl.org/id/ENSGALP00010042113.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:420162", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420162", "resource": "KEGG Pathway" }, { "id": "R-GGA-1483255", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1483255", "resource": "Reactome", "description": "PI Metabolism" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A4X1VRK3-1", "protein_name": "Tumor necrosis factor alpha-induced protein 8-like protein 1", "gene_name": "TNFAIP8L1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDTFSTKSLALQAQKKLLSKMASRTVAAAFIDDTSSEVLDELYRATKEFTRSRKEAQKVVKNLVKVAVKLGVLLRGGQLGAEELARLQSFRQQARRLAMTAVSFHQVDFTFDRRVLAASLLECRDLLHQAAGAHLTAKSHGRINHVFGHFADCDFLAALYGPAEPYRSHLRRICEGLTRMLDEGSI", "length": 186 }, "evidence": [ { "id": "F1NZ26", "url": "https://omabrowser.org/oma/group/F1NZ26/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8I5ZY03-1", "protein_name": "Tumor necrosis factor alpha-induced protein 8-like protein 1", "gene_name": "Tnfaip8l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": 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necrosis factor alpha-induced protein 8-like protein 1", "gene_name": "Tnfaip8l1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MDTFSTKSLALQAQKKVLSKMASKAMVAVFVDDTSSEILDELYQATKEFTRSRKEAQRVVKNLVKVAVKLSVLLRAGQLDSDELAQLRRFQGRMRSLAMTALSFHQVDFTFDRRVLAAGLLECRDLLHQATGTHLTAKSHGRINHVFGHFANGDFLAALYSPAEPYRRHLHRICDGLGRMLDEGGI", "length": 186 }, "evidence": [ { "id": "F1NZ26", "url": "https://omabrowser.org/oma/group/F1NZ26/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q7SZE8-1", "protein_name": "Tumor necrosis factor alpha-induced protein 8-like protein 1", "gene_name": "tnfaip8l1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDSFSTKNLALQAQKKLMSKMATKTVANLFIDDTSSEVLDELYRVTKEYTRNRKEAQKIIKNLIKMVVKLGVLYRNGQFNNEELALVERFRKKVHTLAMTAVSFYQIDFTFDRRVMSNLLNDCRELLHQAINRHLTAKSHARINHVFNHFADCDFLATLYGPSEVYRGHLQKICEGVNKMLDEGNL", "length": 186 }, "evidence": [ { "id": "F1NZ26", "url": "https://omabrowser.org/oma/group/F1NZ26/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q8K288-1", "protein_name": "Tumor necrosis factor alpha-induced protein 8-like protein 1", "gene_name": "Tnfaip8l1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDTFSTKSLALQAQKKVLSKMASKAMVAVFVDNTSSEVLDELYQATKEFTRSRKEAQRVVKNLVKVAVKLAVLLRADQLDSNELAQLQRFRGRVRSLAMTALSFHQVDFTFDRRVLATGLLECRDLLHQAIGPHLTAKSHGRINHIFSHFANGDFLAALYSPAEPYRSHLCRICDGLGRMLDEGGI", "length": 186 }, "evidence": [ { "id": "F1NZ26", "url": "https://omabrowser.org/oma/group/F1NZ26/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8WVP5-1", "protein_name": "Tumor necrosis factor alpha-induced protein 8-like protein 1", "gene_name": "TNFAIP8L1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDTFSTKSLALQAQKKLLSKMASKAVVAVLVDDTSSEVLDELYRATREFTRSRKEAQKMLKNLVKVALKLGLLLRGDQLGGEELALLRRFRHRARCLAMTAVSFHQVDFTFDRRVLAAGLLECRDLLHQAVGPHLTAKSHGRINHVFGHLADCDFLAALYGPAEPYRSHLRRICEGLGRMLDEGSL", "length": 186 }, "evidence": [ { "id": "F1NZ26", "url": "https://omabrowser.org/oma/group/F1NZ26/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1NZ26", "url": "https://www.uniprot.org/uniprotkb/F1NZ26" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "F1NZ26", "url": "https://www.uniprot.org/uniprotkb/F1NZ26" } ], "pmid": "" } ] }, { "name": 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}, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1NZJ0-1", "uniprot_ac": "F1NZJ0", "uniprot_id": "F1NZJ0_CHICK", "mass": { "chemical_mass": 46562.0, "monoisotopic_mass": 46562.0 }, "refseq": { "ac": "NP_001026439", "name": "glycosaminoglycan xylosylkinase", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026439" }, "gene_names": [ { "name": "FAM20B", "type": "recommended", "evidence": [ { "id": "F1NZJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NZJ0" } ] }, { "name": "FAM20B", "type": "synonym", "evidence": [ { "id": "NP_001026439", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026439" } ] } ], "protein_names": [ { "name": "FAM20B, glycosaminoglycan xylosylkinase", "type": "synonym", "evidence": [ { "id": "F1NZJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NZJ0/entry#names_and_taxonomy" } ] }, { "name": "family with sequence similarity 20 member B", "type": "synonym", "evidence": [ { "id": "NP_001026439", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026439" } ] }, { "name": "glycosaminoglycan xylosylkinase", "type": "synonym", "evidence": [ { "id": "NP_001026439", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026439" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ720888.1, HAEL01006129.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992440 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000237.1. On Sep 23, 2021 this sequence version replaced NP_001026439.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001026439", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026439" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NZJ0", "url": "https://www.uniprot.org/uniprotkb/F1NZJ0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "FAM20B", "url": "https://www.uniprot.org/uniprotkb/F1NZJ0", "locus": { "chromosome": "8", "start_pos": 6257442, "end_pos": 6276492, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010011193", "url": "https://www.ensembl.org/id/ENSGALG00010011193" } ] } } ], "crossref": [ { "id": "F1NZJ0", "url": "https://alphafold.ebi.ac.uk/entry/F1NZJ0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000004227", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000004227", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd10470", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd10470", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "424427", "url": "https://www.ncbi.nlm.nih.gov/gene/424427", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR009581", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009581", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024869", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024869", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:424427", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424427", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "AVWEDDM", "url": "https://omabrowser.org/oma/group/AVWEDDM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1NZJ0", "url": "https://www.orthodb.org/?gene=F1NZJ0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12450", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12450", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12450:SF14", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12450:SF14", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF06702", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06702", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-1971475", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1971475", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001026439", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026439", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1NZJ0", "url": "https://www.uniprot.org/uniprotkb/F1NZJ0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NZJ0-1", "url": "https://www.uniprot.org/uniprotkb/F1NZJ0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKLKQRVVLLAILLVIFIFTKVFLIDNLDTSAANREDQRAFHRMMASLRVELDPRLDHTLQSPWEIAAQWVVPREVYPEETPELGAVMHAMSTKKIIKADVGYKGTQLKALLILEGGQKVVFKPKRYARDYVVEGEPYAGYDRHNAEVAAFHLDRILGFRRAPLVVGRFVNLRTEIKPVATEQLLGTFMTVGNNTCFYGKCYYCRETEPACADGDIMEGSVTLWLPDVWPLQKHRHPWGRTYREGKLARWEYDESYCDAVKKTSPYDSGPRLLDIIDTAIFDYLIGNADRHHYESFQDDEGASMLILLDNAKSFGNPALDERSILAPLYQCCIIRVSTWNRLNYLKNGVLKSALKTAMSHDPISPVLSDPHLDALDQRLLSILATVKQCTDQFGPDVVLVEDRMTLSHL", "length": 409, "header": "tr|F1NZJ0-1|F1NZJ0_CHICK Isoform 1 of FAM20B, glycosaminoglycan xylosylkinase OS=Gallus gallus OX=9031 GN=FAM20B PE=1 SV=1 CANONICAL=F1NZJ0-1" }, "isoforms": [ { "isoform_ac": "F1NZJ0-1", "url": "https://www.uniprot.org/uniprotkb/F1NZJ0/entry#F1NZJ0-1", "sequence": { "sequence": "MKLKQRVVLLAILLVIFIFTKVFLIDNLDTSAANREDQRAFHRMMASLRVELDPRLDHTLQSPWEIAAQWVVPREVYPEETPELGAVMHAMSTKKIIKADVGYKGTQLKALLILEGGQKVVFKPKRYARDYVVEGEPYAGYDRHNAEVAAFHLDRILGFRRAPLVVGRFVNLRTEIKPVATEQLLGTFMTVGNNTCFYGKCYYCRETEPACADGDIMEGSVTLWLPDVWPLQKHRHPWGRTYREGKLARWEYDESYCDAVKKTSPYDSGPRLLDIIDTAIFDYLIGNADRHHYESFQDDEGASMLILLDNAKSFGNPALDERSILAPLYQCCIIRVSTWNRLNYLKNGVLKSALKTAMSHDPISPVLSDPHLDALDQRLLSILATVKQCTDQFGPDVVLVEDRMTLSHL", "length": 409, "header": "tr|F1NZJ0-1|F1NZJ0_CHICK Isoform 1 of FAM20B, glycosaminoglycan xylosylkinase OS=Gallus gallus OX=9031 GN=FAM20B PE=1 SV=1 CANONICAL=F1NZJ0-1" }, "locus": { "chromosome": "8", "start_pos": 6271223, "end_pos": 6257970, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026753.1", "url": "https://www.ensembl.org/id/ENSGALT00010026753.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015255.1", "url": "https://www.ensembl.org/id/ENSGALP00010015255.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:424427", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424427", "resource": "KEGG Pathway" }, { "id": "R-GGA-1971475", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1971475", "resource": "Reactome", "description": "Glycosaminoglycan-protein linkage region biosynthesis" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A9J7G0C5-1", "protein_name": "Glycosaminoglycan xylosylkinase isoform X1", "gene_name": "Fam20b", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MKLKQRVVLLAILLVIFIFTKVFLIDNLDTSAANREDQRAFHRMMSGLRVELVPKLDHTLQSPWEIAAQWVVPREVYPEETPELGAIMHAMATKKIIKADVGYKGTQLKALLILEGGQKVVFKPKRSPSGSGVQLNSHRYSRDYVVEGEPYAGYDRHNAEVAAFHLDRILGFRRAPLVVGRYVNLRTEIKPVATEQLLSTFLTVGNNTCFYGKCYYCRETEPACADGDMMEGSITLWLPDVWPLQKHRHPWGRTYREGKLARWEYDESYCDAVKKTSPYDSGPRLLDIIDTAVFDYLIGNADRHHYESFQDDEGASMLILLDNAKSFGNPSLDERSILAPLYQCCIIRVSTWNRLNYLKNGVLKSALKSAMAHDPISPVLSDPHLDTVDQRLLNVLATVKQCTDQFGMDTVLVEDRMPLSHL", "length": 422 }, "evidence": [ { "id": "F1NZJ0", "url": "https://omabrowser.org/oma/group/F1NZJ0/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "D3ZUZ4-1", "protein_name": "FAM20B, glycosaminoglycan xylosylkinase", "gene_name": "Fam20b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKLKQRVVVLAILLVIFIFTKVFLIDNLDTSAANREDQRAFHRMMTGLRVELVPKLDHTLQSPWEIAAQWVVPREVYPEETPELGAVMHAMATKKIIKADVGYKGTQLKALLTLEGGQKVVFKPKRYSRDYVVEGEPYAGYDRHNAEVAAFHLDRILGFRRAPLVVGRYVNLRTEVKPVATEQLLSTFLTVGNNTCFYGKCYYCRETEPACADGDMMEGSITLWLPDVWPLQKHRHPWGRTYREGKLARWEYDESYCDAVKKTSPYDSGPRLLDIIDTAVFDYLIGNADRHHYESFQDDEGASMLILLDNAKSFGNPSLDERSILAPLYQCCIIRVSTWNRLNYLKNGVLKSALKSAMAHDPIAPVLSDPHLDTVDQRLLNVLATIKQCTDQFGMDTVLVEDRMPLSHL", "length": 409 }, "evidence": [ { "id": "F1NZJ0", "url": "https://omabrowser.org/oma/group/F1NZJ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1S6Y3-1", "protein_name": "FAM20B glycosaminoglycan xylosylkinase", "gene_name": "FAM20B", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MKLKQRVVLLAILLVIFIFTKVFLIDNLDTSAANREDQRAFHRMMAGLRVELVPKLDHTLQSPWEIAAQWVVPREVYPEETPELGAIMHAMATKKIIKADVGYKGTQLKALLILEGGQKVVFKPKRYNRDYVVEGEPYAGYDRHNAEVAAFHLDRILGFRRAPLVVGRFVNLRTEIKPVATEQLLSTFLTVGNNTCFYGKCYYCRETEPACADGDTMEGSVTLWLPDVWPLQKHRHPWGRTYREGKLARWEYDESYCDAVKKTSPYDSGPRLLDIIDTAVFDYLIGNADRHHYESFQDDEGASMLILLDNAKSFGNPSLDERSILAPLYQCCIIRVSTWNRLNSLKNGVLKSALKSAMAHDPISPVLSDPHLDALDQRLLSVLATVKQCTDQFGMDTVLVEDRMPLSHL", "length": 409 }, "evidence": [ { "id": "F1NZJ0", "url": "https://omabrowser.org/oma/group/F1NZJ0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F6RNG7-1", "protein_name": "FAM20B glycosaminoglycan xylosylkinase", "gene_name": "FAM20B", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MKLKQRVVLLAILLVIFIFTKVFLIDNLDTSAANREDQRAFHRMMAGLRVELVPKLDHTLQSPWEIAAQWVVPREVYPEETPELGAILHAMATKKIIKADVGYKGTQLKALLILEGGQKVVFKPKRYNRDYVVEGEPYAGYDRHNAEVAAFHLDRILGFRRAPLVVGRFVNLRTEIKPVATEQLLSTFLTVGNNTCFYGKCYYCRETEPACADGDTMEGSVTLWLPDVWPLQKHRHPWGRTYREGKLARWEYDESYCDAVKKTSPYDSGPRLLDIIDTAVFDYLIGNADRHHYESFQDDEGASMLILLDNAKSFGNPSLDERSILAPLYQCCIIRVSTWNRLNSLKNGVLKSALKSAMAHDPISPVLSDPHLDAVEQRLLSVLATVKQCTDQFGMDTVLVEDRMPLSHL", "length": 409 }, "evidence": [ { "id": "F1NZJ0", "url": "https://omabrowser.org/oma/group/F1NZJ0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "O75063-1", "protein_name": "Glycosaminoglycan xylosylkinase", "gene_name": "FAM20B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKLKQRVVLLAILLVIFIFTKVFLIDNLDTSAANREDQRAFHRMMTGLRVELAPKLDHTLQSPWEIAAQWVVPREVYPEETPELGAVMHAMATKKIIKADVGYKGTQLKALLILEGGQKVVFKPKRYSRDHVVEGEPYAGYDRHNAEVAAFHLDRILGFHRAPLVVGRFVNLRTEIKPVATEQLLSTFLTVGNNTCFYGKCYYCRETEPACADGDIMEGSVTLWLPDVWPLQKHRHPWGRTYREGKLARWEYDESYCDAVKKTSPYDSGPRLLDIIDTAVFDYLIGNADRHHYESFQDDEGASMLILLDNAKSFGNPSLDERSILAPLYQCCIIRVSTWNRLNYLKNGVLKSALKSAMAHDPISPVLSDPHLDAVDQRLLSVLATVKQCTDQFGMDTVLVEDRMPLSHL", "length": 409 }, "evidence": [ { "id": "F1NZJ0", "url": "https://omabrowser.org/oma/group/F1NZJ0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q5RH51-1", "protein_name": "Glycosaminoglycan xylosylkinase", "gene_name": "fam20b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MKLKQRVVVLCAVLFLLGLAKVFLLDGGEGSAASRRDLRAFRKMEASLSLAKGARLTHTLQSPWEVAAQWVGPREVYPDETPELAAVLNALATAHVERADVGYKGTQLKALLVLDGGQKVVFKPKRYVRDYVVEGEPYAGYDRHNAEIAAFHLDRILGFRRAPLVVGRFMNLRTEIKPVATDQLLSTFLMHGNNTCFYGKCYYCRETEPACAEGDVMEGSVTLWLPDVWPLQKHRHPWGRTYREGKLARWEYDESYCEAVKKMPPYDAGPRLLDVIDTSIFDYLIGNADRHHYESFQDDGGASMLILLDNAKSFGNPSLDERSILAPLYQCCMVRVSTWNRLNLLKGGVLSSAMRQATAHDPAFPVLTGAHLTALDRRLNGVLATVRQCMETQGSENTLIEDRMNLPHP", "length": 409 }, "evidence": [ { "id": "F1NZJ0", "url": "https://omabrowser.org/oma/group/F1NZJ0/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q8VCS3-1", "protein_name": "Glycosaminoglycan xylosylkinase", "gene_name": "Fam20b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKLKQRVVLLAILLVIFIFTKVFLIDNLDTSAANREDQRAFHRMMTGLRVELVPKLDHTLQSPWEIAAQWVVPREVYPEETPELGAIMHAMATKKIIKADVGYKGTQLKALLILEGGQKVVFKPKRYSRDYVVEGEPYAGYDRHNAEVAAFHLDRILGFRRAPLVVGRYVNLRTEVKPVATEQLLSTFLTVGNNTCFYGKCYYCRETEPACADGDMMEGSVTLWLPDVWPLQKHRHPWGRTYREGKLARWEYDESYCDAVKKTSPYDSGPRLLDIIDTAVFDYLIGNADRHHYESFQDDEGASMLILLDNAKSFGNPSLDERSILAPLYQCCIIRVSTWNRLNYLKNGVLKSALKSAMAHDPISPVLSDPHLDTVDQRLLNVLATIKQCTDQFGTDTVLVEDRMPLSHL", "length": 409 }, "evidence": [ { "id": "F1NZJ0", "url": "https://omabrowser.org/oma/group/F1NZJ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q95T10-1", "protein_name": "Glycosaminoglycan xylosylkinase homolog", "gene_name": "", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MNKRSVIIAGIVASLLGLALGANFYFMYYLSAEEGHLASVRALENMIRHKMRHLKPNYLNRNPRFFMFRNKLLKNYKAAPYENASVLWDIANWWPHENEVYPLYDSSMGQLLETLRREPITRVSNLGRGTQLKLLVRLSHQQKVIFKPQWYPREEVIDGMIYSGKDRHTAEVYAFYLGAVLDFRWTPIVVGRVVNLKKEIYAKGDPELQQTINIETDEDGREKYCLFGKCHYCNEEETVCGDERHNIEGVLIYIVPGTLAKRRSPWQRTYKDDKRAPWEDDMTYCKSLKNKMETIRLLDLIDASIFDYLIQNGDRHHYETREERVVLIDNGKAFGNPNKDHLDILAPLYQCCLLRKSTWDRLQVFSGGVLTEIIDRLSKQDALYPLITDKHKKGVERRLLVVYAVVEHCMDIEGDKMFKTL", "length": 421 }, "evidence": [ { "id": "F1NZJ0", "url": "https://omabrowser.org/oma/group/F1NZJ0/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "F1NZJ0", "url": "https://www.uniprot.org/uniprotkb/F1NZJ0" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "F1NZJ0", "url": "https://www.uniprot.org/uniprotkb/F1NZJ0" } ], "pmid": "" }, { "name": "phosphotransferase activity, alcohol group as acceptor", "id": "GO:0016773", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016773", "evidence": [ { "database": "UniProtKB", "id": "F1NZJ0", "url": "https://www.uniprot.org/uniprotkb/F1NZJ0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "F1NZJ0", "url": "https://www.uniprot.org/uniprotkb/F1NZJ0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "proteoglycan biosynthetic process", "id": "GO:0030166", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030166", "evidence": [ { "database": "UniProtKB", "id": "F1NZJ0", "url": "https://www.uniprot.org/uniprotkb/F1NZJ0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 193, "end_pos": 195, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1NZJ0-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 409, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1NZJ0-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1NZJ0" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1NZJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NZJ0" }, { "id": "PF06702", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06702" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "FAM20 C-terminal", "eco_id": "ECO_0000259", "start_pos": 188, "end_pos": 397, "start_aa": "Phe", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [ { "evidence": [ { "id": "F1NZJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NZJ0#function" }, { "id": "F1NZJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NZJ0" }, { "id": "PIRSR624869-3", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR624869-3" } ], "binding_site_uniprot": 142, "amino_acid": "Asp", "chebi_lig_id": "CHEBI_29035", "ligand": "Mn(2+)", "ligand_label": "", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 142, "end_pos": 142, "start_aa": "Asp", "end_aa": "Asp", "glycosite_overlap": "" }, { "evidence": [ { "id": "F1NZJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NZJ0#function" }, { "id": "F1NZJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NZJ0" }, { "id": "PIRSR624869-3", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR624869-3" } ], "binding_site_uniprot": 309, "amino_acid": "Asp", "chebi_lig_id": "CHEBI_29035", "ligand": "Mn(2+)", "ligand_label": "", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 309, "end_pos": 309, "start_aa": "Asp", "end_aa": "Asp", "glycosite_overlap": "" } ], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 193, "end_pos": 195 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1NZJ3-1", "uniprot_ac": "F1NZJ3", "uniprot_id": "F1NZJ3_CHICK", "mass": { "chemical_mass": 26800.0, "monoisotopic_mass": 26800.0 }, "refseq": { "ac": "NP_001012293", "name": "homeobox protein Hox-D4", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012293" }, "gene_names": [ { "name": "HOXD4", "type": "recommended", "evidence": [ { "id": "F1NZJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NZJ3" } ] }, { "name": "Chox-a", "type": "synonym", "evidence": [ { "id": "NP_001012293", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012293" } ] }, { "name": "HOXD4", "type": "synonym", "evidence": [ { "id": "NP_001012293", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012293" } ] } ], "protein_names": [ { "name": "Homeobox protein Hox-D4", "type": "recommended", "evidence": [ { "id": "F1NZJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NZJ3/entry#names_and_taxonomy" } ] }, { "name": "homeobox protein Hox-A", "type": "synonym", "evidence": [ { "id": "NP_001012293", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012293" } ] }, { "name": "homeobox protein Hox-D4", "type": "synonym", "evidence": [ { "id": "NP_001012293", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012293" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: HAEL01003354.1, SRR13267657.13720.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN06140854 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000236.1. On Dec 21, 2012 this sequence version replaced XP_421990.1. Sequence Note: This RefSeq record was created from genomic sequence data because no single transcript from the same breed was available for the full length of the gene. The extent of this transcript is supported by transcript alignments and orthologous data.", "evidence": [ { "database": "RefSeq", "id": "NP_001012293", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012293" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NZJ3", "url": "https://www.uniprot.org/uniprotkb/F1NZJ3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "HOXD4", "url": "https://www.uniprot.org/uniprotkb/F1NZJ3", "locus": { "chromosome": "7", "start_pos": 15898314, "end_pos": 15900370, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010024746", "url": "https://www.ensembl.org/id/ENSGALG00010024746" } ] } } ], "crossref": [ { "id": "F1NZJ3", "url": "https://alphafold.ebi.ac.uk/entry/F1NZJ3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000023419", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000023419", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00086", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00086", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "424139", "url": "https://www.ncbi.nlm.nih.gov/gene/424139", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001356", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001356", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001827", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001827", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009057", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009057", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017970", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017970", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017995", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017995", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020479", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020479", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050609", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050609", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:424139", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424139", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PGQGEHC", "url": "https://omabrowser.org/oma/group/PGQGEHC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1NZJ3", "url": "https://www.orthodb.org/?gene=F1NZJ3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45771", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45771", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45771:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45771:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00046", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00046", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001012293", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012293", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1NZJ3", "url": "https://www.uniprot.org/uniprotkb/F1NZJ3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NZJ3-1", "url": "https://www.uniprot.org/uniprotkb/F1NZJ3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAMSSYMVNSKYVDPKFPPCEEYLQSSYLGEQGAEYYGASQGSDFQHQGLYPRSNYSEQPFGCAGAQGSAVQPRGHGQEQSAPPSHFPGQAEHCPPPPMSNSRACGQQPALKAPHGSAVKQPAVVYPWMKKVHVNSVNPNYSGGEPKRSRTAYTRQQVLELEKEFHFNRYLTRRRRIEIAHTLCLSERQIKIWFQNRRMKWKKDHKLPNTKGRSSSSASNPHLQTVPKDHQTDLTTL", "length": 237, "header": "tr|F1NZJ3-1|F1NZJ3_CHICK Isoform 1 of Homeobox protein Hox-D4 OS=Gallus gallus OX=9031 GN=HOXD4 PE=3 SV=1 CANONICAL=F1NZJ3-1" }, "isoforms": [ { "isoform_ac": "F1NZJ3-1", "url": "https://www.uniprot.org/uniprotkb/F1NZJ3/entry#F1NZJ3-1", "sequence": { "sequence": "MAMSSYMVNSKYVDPKFPPCEEYLQSSYLGEQGAEYYGASQGSDFQHQGLYPRSNYSEQPFGCAGAQGSAVQPRGHGQEQSAPPSHFPGQAEHCPPPPMSNSRACGQQPALKAPHGSAVKQPAVVYPWMKKVHVNSVNPNYSGGEPKRSRTAYTRQQVLELEKEFHFNRYLTRRRRIEIAHTLCLSERQIKIWFQNRRMKWKKDHKLPNTKGRSSSSASNPHLQTVPKDHQTDLTTL", "length": 237, "header": "tr|F1NZJ3-1|F1NZJ3_CHICK Isoform 1 of Homeobox protein Hox-D4 OS=Gallus gallus OX=9031 GN=HOXD4 PE=3 SV=1 CANONICAL=F1NZJ3-1" }, "locus": { "chromosome": "7", "start_pos": 15900263, "end_pos": 15899255, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010060408.1", "url": "https://www.ensembl.org/id/ENSGALT00010060408.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010037167.1", "url": "https://www.ensembl.org/id/ENSGALP00010037167.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:424139", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424139", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D4ACE1-1", "protein_name": "Homeobox protein Hox-D4", "gene_name": "Hoxd4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAMSSYMVNSKYVDPKFPPCEEYLQGGYLGEQGADYYGSGAQGSDFQPPGLYPRPDFGEQPFGGGGPGPGSALPARGHGQEPSGPGSHYSAPGEPCPAPPPAPLPGARACSQPTGPKQPPPGTALKQPAVVYPWMKKVHVNSVNPNYTGGEPKRSRTAYTRQQVLELEKEFHFNRYLTRRRRIEIAHTLCLSERQIKIWFQNRRMKWKKDHKLPNTKGRSSSSSSSCSSSAAPSQHLQPMAKDHHTDLTTL", "length": 251 }, "evidence": [ { "id": "F1NZJ3", "url": "https://omabrowser.org/oma/group/F1NZJ3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1RZG0-1", "protein_name": "Homeobox protein Hox-D4", "gene_name": "HOXD4", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAMSSYMVNSKYVDPKFPPCEEYLQGGYLGEQGADYYSSGAQGADFQPPGLYPRPDFSEQTFGGGGPGPGSALPTRSHGPEPSGPGGHYGAPGEPCPAPPAPPPAPLPGARACSQPGGPKQPPPGTALKQPAVVYPWMKKVHVNSVNPNYTGGEPKRSRTAYTRQQVLELEKEFHFNRYLTRRRRIEIAHTLCLSERQIKIWFQNRRMKWKKDHKLPNTKGRSSSSSSSSSSCSSSAAPGQHLQPLAKDHHTDLTTL", "length": 257 }, "evidence": [ { "id": "F1NZJ3", "url": "https://omabrowser.org/oma/group/F1NZJ3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P09016-1", "protein_name": "Homeobox protein Hox-D4", "gene_name": "HOXD4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVMSSYMVNSKYVDPKFPPCEEYLQGGYLGEQGADYYGGGAQGADFQPPGLYPRPDFGEQPFGGSGPGPGSALPARGHGQEPGGPGGHYAAPGEPCPAPPAPPPAPLPGARAYSQSDPKQPPSGTALKQPAVVYPWMKKVHVNSVNPNYTGGEPKRSRTAYTRQQVLELEKEFHFNRYLTRRRRIEIAHTLCLSERQIKIWFQNRRMKWKKDHKLPNTKGRSSSSSSSSSCSSSVAPSQHLQPMAKDHHTDLTTL", "length": 255 }, "evidence": [ { "id": "F1NZJ3", "url": "https://omabrowser.org/oma/group/F1NZJ3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P10628-1", "protein_name": "Homeobox protein Hox-D4", "gene_name": "Hoxd4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAMSSYMVNSKYVDPKFPPCEEYLQGGYLGEQGADYYGSGAQGADFQPSGLYPRPDFGEQPFGGGGPGPGSALPARGHGQEPSGPGSHYGAPGERCPAPPPAPLPGARACSQPTGPKQPPPGTALKQPAVVYPWMKKVHVNSVNPNYTGGEPKRSRTAYTRQQVLELEKEFHFNRYLTRRRRIEIAHTLCLSERQIKIWFQNRRMKWKKDHKLPNTKGRSSSSSSCSSSAAPGQHLQPMAKDHHTDLTTL", "length": 250 }, "evidence": [ { "id": "F1NZJ3", "url": "https://omabrowser.org/oma/group/F1NZJ3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "F1NZJ3", "url": "https://www.uniprot.org/uniprotkb/F1NZJ3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "F1NZJ3", "url": "https://www.uniprot.org/uniprotkb/F1NZJ3" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "F1NZJ3", "url": "https://www.uniprot.org/uniprotkb/F1NZJ3" } ], "pmid": "" }, { "name": "anterior/posterior pattern specification", "id": "GO:0009952", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009952", "evidence": [ { "database": "UniProtKB", "id": "F1NZJ3", "url": "https://www.uniprot.org/uniprotkb/F1NZJ3" } ], "pmid": "" }, { "name": "embryonic skeletal system morphogenesis", "id": "GO:0048704", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048704", "evidence": [ { "database": "UniProtKB", "id": "F1NZJ3", "url": "https://www.uniprot.org/uniprotkb/F1NZJ3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "F1NZJ3", "url": "https://www.uniprot.org/uniprotkb/F1NZJ3" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "F1NZJ3", "url": "https://www.uniprot.org/uniprotkb/F1NZJ3" } ], "pmid": "" }, { "name": "DNA-binding transcription activator activity, RNA polymerase II-specific", "id": "GO:0001228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001228", "evidence": [ { "database": "UniProtKB", "id": "F1NZJ3", "url": "https://www.uniprot.org/uniprotkb/F1NZJ3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 140, "end_pos": 142, "annotation": "n_glycosylation_sequon" }, { "start_pos": 55, "end_pos": 57, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1NZJ3-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 237, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1NZJ3-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1NZJ3" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1NZJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NZJ3" }, { "id": "PS50071", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50071" }, { "id": "PRU00108", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00108" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Homeobox", "eco_id": "ECO_0000259", "start_pos": 144, "end_pos": 204, "start_aa": "Gly", "end_aa": "Asp", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 140, "end_pos": 142 }, { "start_pos": 55, "end_pos": 57 } ] }, "class_list": [], 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"table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { 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"total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1NZY0-1", "uniprot_ac": "F1NZY0", "uniprot_id": "F1NZY0_CHICK", "mass": { "chemical_mass": 41069.0, "monoisotopic_mass": 41069.0 }, "refseq": { "ac": "XP_001232445", "name": "guanine nucleotide-binding protein G(z) subunit alpha", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001232445" }, "gene_names": [ { "name": "GNAZ", "type": "recommended", "evidence": [ { "id": "F1NZY0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NZY0" } ] }, { "name": "GNAZ", "type": "synonym", "evidence": [ { "id": "XP_001232445", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001232445" } ] } ], "protein_names": [ { "name": "Guanine nucleotide-binding protein G(z) subunit alpha", "type": "recommended", "evidence": [ { "id": "F1NZY0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NZY0/entry#names_and_taxonomy" } ] }, { "name": "G(x) alpha chain", "type": "synonym", "evidence": [ { "id": "F1NZY0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NZY0/entry#names_and_taxonomy" } ] }, { "name": "Gz-alpha", "type": "synonym", "evidence": [ { "id": "F1NZY0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NZY0/entry#names_and_taxonomy" } ] }, { "name": "guanine nucleotide-binding protein G(z) subunit alpha", "type": "synonym", "evidence": [ { "id": "XP_001232445", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001232445" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052546.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_001232445", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001232445" } ] }, { "annotation": "Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems.", "evidence": [ { "database": "UniProtKB", "id": "F1NZY0", "url": "https://www.uniprot.org/uniprotkb/F1NZY0#function" }, { "database": "UniProtKB", "id": "ARBA00003069", "url": "https://www.uniprot.org/uniprotkb/ARBA00003069#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NZY0", "url": "https://www.uniprot.org/uniprotkb/F1NZY0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "GNAZ", "url": "https://www.uniprot.org/uniprotkb/F1NZY0", "locus": { "chromosome": "15", "start_pos": 8705941, "end_pos": 8752402, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010026569", "url": "https://www.ensembl.org/id/ENSGALG00010026569" } ] } } ], "crossref": [ { "id": "F1NZY0", "url": "https://alphafold.ebi.ac.uk/entry/F1NZY0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000006719", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000006719", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00066", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00066", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "770226", "url": "https://www.ncbi.nlm.nih.gov/gene/770226", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001019", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001019", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001408", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001408", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011025", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011025", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:770226", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:770226", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "ANSHWFK", "url": "https://omabrowser.org/oma/group/ANSHWFK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1NZY0", "url": "https://www.orthodb.org/?gene=F1NZY0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10218", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10218", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10218:SF65", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10218:SF65", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00503", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00503", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-418597", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-418597", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_001232445", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001232445", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1NZY0", "url": "https://www.uniprot.org/uniprotkb/F1NZY0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NZY0-1", "url": "https://www.uniprot.org/uniprotkb/F1NZY0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGCRQSSEEKEAARRSRRIDRHLRSESQRQRREIKLLLLGTSNSGKSTIVKQMKIIHSGGFNLEACKEYKPLIIYNAIDSLTRIIRALATLKIEFHNPDRAYDAVQLFALTGPAESKGEITPELLGVMKRLWADPGVQECFCRSNEYHLEDNAAYYLNDLERIAALDYIPTVEDILRSRDMTTGIVENKFTFKELTFKMVDVGGQRSERKKWIHCFEGVTAIIFCVELSGYDLKLYEDNQTSRMAESLRLFDSICNNNWFINTSLILFLNKKDLLAEKIRRIPLTVCFPEYKGQNTYEEAAVYIQRQFEDLNRNKETKEIYSHFTCATDTSNIQFVFDAVTDVIIQNNLKYIGLC", "length": 355, "header": "tr|F1NZY0-1|F1NZY0_CHICK Isoform 1 of Guanine nucleotide-binding protein G(z) subunit alpha OS=Gallus gallus OX=9031 GN=GNAZ PE=3 SV=2 CANONICAL=F1NZY0-1" }, "isoforms": [ { "isoform_ac": "F1NZY0-1", "url": "https://www.uniprot.org/uniprotkb/F1NZY0/entry#F1NZY0-1", "sequence": { "sequence": "MGCRQSSEEKEAARRSRRIDRHLRSESQRQRREIKLLLLGTSNSGKSTIVKQMKIIHSGGFNLEACKEYKPLIIYNAIDSLTRIIRALATLKIEFHNPDRAYDAVQLFALTGPAESKGEITPELLGVMKRLWADPGVQECFCRSNEYHLEDNAAYYLNDLERIAALDYIPTVEDILRSRDMTTGIVENKFTFKELTFKMVDVGGQRSERKKWIHCFEGVTAIIFCVELSGYDLKLYEDNQTSRMAESLRLFDSICNNNWFINTSLILFLNKKDLLAEKIRRIPLTVCFPEYKGQNTYEEAAVYIQRQFEDLNRNKETKEIYSHFTCATDTSNIQFVFDAVTDVIIQNNLKYIGLC", "length": 355, "header": "tr|F1NZY0-1|F1NZY0_CHICK Isoform 1 of Guanine nucleotide-binding protein G(z) subunit alpha OS=Gallus gallus OX=9031 GN=GNAZ PE=3 SV=2 CANONICAL=F1NZY0-1" }, "locus": { "chromosome": "15", "start_pos": 8733059, "end_pos": 8707682, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010064541.1", "url": "https://www.ensembl.org/id/ENSGALT00010064541.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039560.1", "url": "https://www.ensembl.org/id/ENSGALP00010039560.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:770226", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:770226", "resource": "KEGG Pathway" }, { "id": "R-GGA-418597", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-418597", "resource": "Reactome", "description": "G alpha (z) signalling events" } ], "orthologs": [ { "uniprot_canonical_ac": "A0ABI0P4H8-1", "protein_name": "Radial spoke head 14 homolog", "gene_name": "RSPH14", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MADAKISMYLPPNVNPTQAAIAYGCRALPKLNEELQSDDLLTRQKALMALCDLMHDPEHVYTAISIGCLESLKALLKDTNDLVRIKTTEVLCIMATHNVGREGFLEHNVIQALSFLMSDAQPACRENLYTAFKHLAQLPAGALGIVNSGLIPSLVWKLQREEEEIQVLLLDTLAACLTEDATEALASRAVPFLKEKLLSTNCNIRSKAARTLIAVSVPPEGKIQVWQHDVIPILVHLLKDRDEEVQANAAGALMNATVTTEGKYAALDAEATRPLLQLLTSSLSKARLNAIKALTMLAEAPEGRKLLQPHVATFRALEEDFSPAVQRAAQIAIRVIEWKP", "length": 340 }, "evidence": [ { "id": "F1NZY0", "url": "https://omabrowser.org/oma/group/F1NZY0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1RLT6-1", "protein_name": "Guanine nucleotide-binding protein G(z) subunit alpha", "gene_name": "GNAZ", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGCRQSSEEKEAARRSRRIDRHLRSESQRQRREIKLLLLGTSNSGKSTIVKQMKIIHSGGFNLEACKEYKPLIIYNAIDSLTRIIRALAALKIDFHNPDRAYDAVQLFALTGPAESKGEITPELLGVMRRLWADPGAQACFGRSSEYHLEDNAAYYLNDLERIAAPDYVPTVEDILRSRDMTTGIVENKFTFKELTFKMVDVGGQRSERKKWIHCFEGVTAIIFCVELSGYDLKLYEDNQTSRMAESLRLFDSICNNNWFVSTSLILFLNKKDLLAQKIRRIPLTVCFPEYGGQNTYEEAAVYIQRQFEDLNRNKETKEIYSHFTCATDTSNIQFVFDAVTDVIIQNNLKYIGLC", "length": 355 }, "evidence": [ { "id": "F1NZY0", "url": "https://omabrowser.org/oma/group/F1NZY0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3HMY7-1", "protein_name": "Guanine nucleotide-binding protein G(z) subunit alpha", "gene_name": "Gnaz", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MGCRQSSEEKEAARRSRRIDRHLRSESQRQRREIKLLLLGTSNSGKSTIVKQMKIIHSGGFNLDACKEYKPLIIYNAIDSLTRIIRALAALKIDFHNPDRAYDAVQLFALTGPAESKGEITPELLGVMRRLWADPGAQACFGRSSEYHLEDNAAYYLNDLERIAAPDYIPTVEDILRSRDMTTGIVENKFTFKELTFKMVDVGGQRSERKKWIHCFEGVTAIIFCVELSGYDLKLYEDNQTSRMAESLRLFDSICNNNWFINTSLILFLNKKDLLAEKIRRIPLSVCFPEYKGQNTYEEAAVYIQRQFEDLNRNKETKEIYSHFTCATDTSNIQFVFDAVTDVIIQNNLKYIGLC", "length": 355 }, "evidence": [ { "id": "F1NZY0", "url": "https://omabrowser.org/oma/group/F1NZY0/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "O70443-1", "protein_name": "Guanine nucleotide-binding protein G(z) subunit alpha", "gene_name": "Gnaz", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGCRQSSEEKEAARRSRRIDRHLRSESQRQRREIKLLLLGTSNSGKSTIVKQMKIIHSGGFNLDACKEYKPLIIYNAIDSLTRIIRALAALKIDFHNPDRAYDAVQLFALTGPAESKGEITPELLGVMRRLWADPGAQACFGRSSEYHLEDNAAYYLNDLERIAAPDYIPTVEDILRSRDMTTGIVENKFTFKELTFKMVDVGGQRSERKKWIHCFEGVTAIIFCVELSGYDLKLYEDNQTSRMAESLRLFDSICNNNWFINTSLILFLNKKDLLAEKIRRIPLSVCFPEYKGQNTYEEAAVYIQRQFEDLNRNKETKEIYSHFTCATDTSNIQFVFDAVTDVIIQNNLKYIGLC", "length": 355 }, "evidence": [ { "id": "F1NZY0", "url": "https://omabrowser.org/oma/group/F1NZY0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P19086-1", "protein_name": "Guanine nucleotide-binding protein G(z) subunit alpha", "gene_name": "GNAZ", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGCRQSSEEKEAARRSRRIDRHLRSESQRQRREIKLLLLGTSNSGKSTIVKQMKIIHSGGFNLEACKEYKPLIIYNAIDSLTRIIRALAALRIDFHNPDRAYDAVQLFALTGPAESKGEITPELLGVMRRLWADPGAQACFSRSSEYHLEDNAAYYLNDLERIAAADYIPTVEDILRSRDMTTGIVENKFTFKELTFKMVDVGGQRSERKKWIHCFEGVTAIIFCVELSGYDLKLYEDNQTSRMAESLRLFDSICNNNWFINTSLILFLNKKDLLAEKIRRIPLTICFPEYKGQNTYEEAAVYIQRQFEDLNRNKETKEIYSHFTCATDTSNIQFVFDAVTDVIIQNNLKYIGLC", "length": 355 }, "evidence": [ { "id": "F1NZY0", "url": "https://omabrowser.org/oma/group/F1NZY0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P19627-1", "protein_name": "Guanine nucleotide-binding protein G(z) subunit alpha", "gene_name": "Gnaz", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGCRQSSEEKEAARRSRRIDRHLRSESQRQRREIKLLLLGTSNSGKSTIVKQMKIIHSGGFNLEACKEYKPLIIYNAIDSLTRIIRALAALKIDFHNPDRAYDAVQLFALTGPAESKGEITPELLGVMRRLWADPGAQACFGRSSEYHLEDNAAYYLNDLERIAAPDYIPTVEDILRSRDMTTGIVENKFTFKELTFKMVDVGGQRSERKKWIHCFEGVTAIIFCVELSGYDLKLYEDNQTSRMAESLRLFDSICNNNWFINTSLILFLNKKDLLSEKIRRIPLSVCFPEYKGQNTYEEAAVYIQRQFEDLNRNKETKEIYSHFTCATDTSNIQFVFDAVTDVIIQNNLKYIGLC", "length": 355 }, "evidence": [ { "id": "F1NZY0", "url": "https://omabrowser.org/oma/group/F1NZY0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P34042-1", "protein_name": "Guanine nucleotide-binding protein alpha-4 subunit", "gene_name": "gpaD", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MRFKCFGSEETEQSSKIDKSIETDRRKLRKDVKLLLLGPGESGKSTIFKQMKIIQEDGGYSVEELLEYRAFVYSNCISQMEALLTASAKLNIELEVENKQRAANVLRRTIGNEPWLLLAADIKHLWEDKGIKETYAQKDKHFQLNDSAAYFFDNIDRYMREDFVPNEQDVLRCRVRTTGIQESEFTFDKIRLKIVDVGGQRSQRRKWIHCFDCVTAVIFVAAMSDYDQVLREDESVNRTRESLALFKEIVNCDYFKETPIVLFLNKKDLFKEKLKRVPLQSCFSDYTGPNKYKDAAMFIQSQYLAQGPSPRTIYTHATCAVDTENIKFVFRAVRQTILSQALEHF", "length": 345 }, "evidence": [ { "id": "F1NZY0", "url": "https://omabrowser.org/oma/group/F1NZY0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 6, "go_terms": [ { "name": "GTPase activity", "id": "GO:0003924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003924", "evidence": [ { "database": "UniProtKB", "id": "F1NZY0", "url": "https://www.uniprot.org/uniprotkb/F1NZY0" } ], "pmid": "" }, { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "F1NZY0", "url": "https://www.uniprot.org/uniprotkb/F1NZY0" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "F1NZY0", "url": "https://www.uniprot.org/uniprotkb/F1NZY0" } ], "pmid": "" }, { "name": "G protein-coupled receptor binding", "id": "GO:0001664", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001664", "evidence": [ { "database": "UniProtKB", "id": "F1NZY0", "url": "https://www.uniprot.org/uniprotkb/F1NZY0" } ], "pmid": "" }, { "name": "G-protein beta/gamma-subunit complex binding", "id": "GO:0031683", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031683", "evidence": [ { "database": "UniProtKB", "id": "F1NZY0", "url": "https://www.uniprot.org/uniprotkb/F1NZY0" } ], "pmid": "" }, { "name": "adenylate cyclase inhibitor activity", "id": "GO:0010855", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010855", "evidence": [ { "database": "UniProtKB", "id": "F1NZY0", "url": "https://www.uniprot.org/uniprotkb/F1NZY0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1NZY0", "url": "https://www.uniprot.org/uniprotkb/F1NZY0" } ], "pmid": "" }, { "name": "dendrite", "id": "GO:0030425", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030425", "evidence": [ { "database": "UniProtKB", "id": "F1NZY0", "url": "https://www.uniprot.org/uniprotkb/F1NZY0" } ], "pmid": "" }, { "name": "synapse", "id": "GO:0045202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045202", "evidence": [ { "database": "UniProtKB", "id": "F1NZY0", "url": "https://www.uniprot.org/uniprotkb/F1NZY0" } ], "pmid": "" }, { "name": "cell body", "id": "GO:0044297", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044297", "evidence": [ { "database": "UniProtKB", "id": "F1NZY0", "url": "https://www.uniprot.org/uniprotkb/F1NZY0" } ], "pmid": "" }, { "name": "heterotrimeric G-protein complex", "id": "GO:0005834", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005834", "evidence": [ { "database": "UniProtKB", "id": "F1NZY0", "url": "https://www.uniprot.org/uniprotkb/F1NZY0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "adenylate cyclase-modulating G protein-coupled receptor signaling pathway", "id": "GO:0007188", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007188", "evidence": [ { "database": "UniProtKB", "id": "F1NZY0", "url": "https://www.uniprot.org/uniprotkb/F1NZY0" } ], "pmid": "" }, { "name": "negative regulation of insulin secretion", "id": "GO:0046676", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046676", "evidence": [ { "database": "UniProtKB", "id": "F1NZY0", "url": "https://www.uniprot.org/uniprotkb/F1NZY0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 239, "end_pos": 241, "annotation": "n_glycosylation_sequon" }, { "start_pos": 262, "end_pos": 264, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1NZY0-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 355, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1NZY0-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1NZY0" } ], "lectin_list": [], "domain_list": [], "binding_sites": [ { "evidence": [ { "id": "F1NZY0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NZY0#function" }, { "id": "F1NZY0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NZY0" }, { "id": "PIRSR601019-2", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR601019-2" } ], "binding_site_uniprot": 182, "amino_acid": "Thr", "chebi_lig_id": "CHEBI_18420", "ligand": "Mg(2+)", "ligand_label": "", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 182, "end_pos": 182, "start_aa": "Thr", "end_aa": "Thr", "glycosite_overlap": "" }, { "evidence": [ { "id": "F1NZY0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NZY0#function" }, { "id": "F1NZY0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NZY0" }, { "id": "PIRSR601019-2", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR601019-2" } ], "binding_site_uniprot": 47, "amino_acid": "Ser", "chebi_lig_id": "CHEBI_18420", "ligand": "Mg(2+)", "ligand_label": "", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 47, "end_pos": 47, "start_aa": "Ser", "end_aa": "Ser", "glycosite_overlap": "" } ], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 239, "end_pos": 241 }, { "start_pos": 262, "end_pos": 264 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1P024-1", "uniprot_ac": "F1P024", "uniprot_id": "F1P024_CHICK", "mass": { "chemical_mass": 27469.0, "monoisotopic_mass": 27469.0 }, "refseq": { "ac": "NP_001264427", "name": "GATA zinc finger domain-containing protein 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264427" }, "gene_names": [ { "name": "GATAD1", "type": "recommended", "evidence": [ { "id": "F1P024", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P024" } ] }, { "name": "GATAD1", "type": "synonym", "evidence": [ { "id": "NP_001264427", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264427" } ] } ], "protein_names": [ { "name": "GATA zinc finger domain-containing protein 1", "type": "recommended", "evidence": [ { "id": "F1P024", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P024/entry#names_and_taxonomy" } ] }, { "name": "GATA zinc finger domain-containing protein 1", "type": "synonym", "evidence": [ { "id": "NP_001264427", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264427" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: BU129567.1, BX934047.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000036.1. On Apr 11, 2013 this sequence version replaced XP_418653.3. Sequence Note: This RefSeq record was created from transcript and genomic sequence data from different strains because no single transcript from the same strain was available for the full length of the gene. The extent of this transcript is supported by transcript alignments and orthologous data.", "evidence": [ { "database": "RefSeq", "id": "NP_001264427", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264427" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1P024", "url": "https://www.uniprot.org/uniprotkb/F1P024" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "GATAD1", "url": "https://www.uniprot.org/uniprotkb/F1P024", "locus": { "chromosome": "2", "start_pos": 22529329, "end_pos": 22526145, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010004899", "url": "https://www.ensembl.org/id/ENSGALG00010004899" } ] } } ], "crossref": [ { "id": "F1P024", "url": "https://alphafold.ebi.ac.uk/entry/F1P024", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000009399", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000009399", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "420551", "url": "https://www.ncbi.nlm.nih.gov/gene/420551", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000679", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000679", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013088", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013088", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039050", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039050", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:420551", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420551", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "LLTDQYC", "url": "https://omabrowser.org/oma/group/LLTDQYC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1P024", "url": "https://www.orthodb.org/?gene=F1P024", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13340", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13340", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13340:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13340:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "NP_001264427", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264427", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1P024", "url": "https://www.uniprot.org/uniprotkb/F1P024", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1P024-1", "url": "https://www.uniprot.org/uniprotkb/F1P024-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPLGLKPTCSVCRSTSSSMWKKGGQGEILCNNCTARSAPPGPAAFATTSAAAQHSNGGGGGGGGKQSKQEIHRRSARLRNTKYKSAPAAEKKVSTKGKGRRHIFKLKNPIKAPESVSTIITAESIFYKGVYYQIGDVVSVVDEQDGKTYYAQIRGFIQDQYCEKSAALTWLIPTQASPKDCFDPASYIIGPEEDLPRKMEYLEFVCHAPSEYFKSRSSPFPTVPTRPEKGYIWTHVGPTPAISIKETVTNNL", "length": 252, "header": "tr|F1P024-1|F1P024_CHICK Isoform 1 of GATA zinc finger domain-containing protein 1 OS=Gallus gallus OX=9031 GN=GATAD1 PE=4 SV=3 CANONICAL=F1P024-1" }, "isoforms": [ { "isoform_ac": "F1P024-1", "url": "https://www.uniprot.org/uniprotkb/F1P024/entry#F1P024-1", "sequence": { "sequence": "MPLGLKPTCSVCRSTSSSMWKKGGQGEILCNNCTARSAPPGPAAFATTSAAAQHSNGGGGGGGGKQSKQEIHRRSARLRNTKYKSAPAAEKKVSTKGKGRRHIFKLKNPIKAPESVSTIITAESIFYKGVYYQIGDVVSVVDEQDGKTYYAQIRGFIQDQYCEKSAALTWLIPTQASPKDCFDPASYIIGPEEDLPRKMEYLEFVCHAPSEYFKSRSSPFPTVPTRPEKGYIWTHVGPTPAISIKETVTNNL", "length": 252, "header": "tr|F1P024-1|F1P024_CHICK Isoform 1 of GATA zinc finger domain-containing protein 1 OS=Gallus gallus OX=9031 GN=GATAD1 PE=4 SV=3 CANONICAL=F1P024-1" }, "locus": { "chromosome": "2", "start_pos": 22529066, "end_pos": 22526232, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010011462.1", "url": "https://www.ensembl.org/id/ENSGALT00010011462.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010006440.1", "url": "https://www.ensembl.org/id/ENSGALP00010006440.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 222, "start_aa": "Thr", "end_pos": 222, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr222", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 239, "start_aa": "Thr", "end_pos": 239, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr239", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:420551", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420551", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A286ZUW8-1", "protein_name": "GATA zinc finger domain-containing protein 1", "gene_name": "GATAD1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MPLGLKPTCSGCKTTSSSMWKKGPQGEILCHHCTGRGGAGGGGTGSGAAGGTGGSGGGGGFGAATFASTSAAPPQSNGGGGGKQSKQEIHRRSARLRNTKYKSAPAAEKKVSTKGKGRRHIFKLKNPIKAPESVSTIITAESIFYKGVYYQIGDVVSVIDEQDGKPYYAQIRGFIQDQYCEKSAALTWLIPTLSSPRDQFDPASYIIGPEEDLPRKMEYLEFVCHAPSEYFKSRSSPFPTVPTRPEKGYIWTHVGPTPAITIKETVANHL", "length": 270 }, "evidence": [ { "id": "F1P024", "url": "https://omabrowser.org/oma/group/F1P024/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0ABK0LHJ5-1", "protein_name": "GATA zinc finger domain-containing protein 1", "gene_name": "Gatad1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPLGLKPTCSMCKTTSSSMWKKSPQGEILCHHCTGRGGGGGGAGVAGGTGGGGGFGTATFATTSAGPSQSNGGGGGKQSKQEIHRRSARLRNTKYKSAPAAEKKVSTKGKGRRHIFKLKNPIKAPESVSTIVTAESIFYKGVYYQIGDVVSVIDEQDGKPYYAQIRGFIQDQYCEKSAALTWLIPTLASPRDQFDPASYIIGPEEDLPRKMEYLEFVCHAPSEYFKSRSRCRPLSSFSSTVLPAHCHAPTMMIMD", "length": 255 }, "evidence": [ { "id": "F1P024", "url": "https://omabrowser.org/oma/group/F1P024/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q1L8G7-1", "protein_name": "GATA zinc finger domain-containing protein 1", "gene_name": "gatad1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MPLGLKPCCAVCKTQSSSMWKKGNQGEILCNGCTGKAVSSGGSGASASSTIQQNNGGGKQSKQEIHRRSARLRSTKYKAPASEKKVSTKGKGRRHIFKLKNPIKAPESVSTIITSESMFYKGIYYQIGDVIKVIDEDDGKPYYAQIRGFVQDQYCEKSAALTWLIPTQASPRDRFDPSTYIVGPEEDLPRKMEYLEFVCHAPSEYFKSRSCPFPTLPVRPEKGYVWTHIGPTPAVAIKETVG", "length": 242 }, "evidence": [ { "id": "F1P024", "url": "https://omabrowser.org/oma/group/F1P024/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q8WUU5-1", "protein_name": "GATA zinc finger domain-containing protein 1", "gene_name": "GATAD1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPLGLKPTCSVCKTTSSSMWKKGAQGEILCHHCTGRGGAGSGGAGSGAAGGTGGSGGGGFGAATFASTSATPPQSNGGGGGKQSKQEIHRRSARLRNTKYKSAPAAEKKVSTKGKGRRHIFKLKNPIKAPESVSTIITAESIFYKGVYYQIGDVVSVIDEQDGKPYYAQIRGFIQDQYCEKSAALTWLIPTLSSPRDQFDPASYIIGPEEDLPRKMEYLEFVCHAPSEYFKSRSSPFPTVPTRPEKGYIWTHVGPTPAITIKESVANHL", "length": 269 }, "evidence": [ { "id": "F1P024", "url": "https://omabrowser.org/oma/group/F1P024/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q920S3-1", "protein_name": "GATA zinc finger domain-containing protein 1", "gene_name": "Gatad1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPLGLKPTCSMCKTTSSSMWKKSPQGEILCHHCTGRGGGGAGVAGGTGGGGGGGGGFGTTTFATTSAGPSQSNGGGGGKQSKQEIHRRSARLRNTKYKSAPAAEKKVSTKGKGRRHIFKLKNPIKAPESVSTIVTAESIFYKGVYYQIGDVVSVIDEQDGKPYYAQIRGFIQDQYCEKSAALTWLIPTLASPRDQFDPASYIIGPEEDLPRKMEYLEFVCHAPSEYFKSRSSPFPTVPTRPEKGYIWTHVGPTPAITIKETVANHL", "length": 266 }, "evidence": [ { "id": "F1P024", "url": "https://omabrowser.org/oma/group/F1P024/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1P024", "url": "https://www.uniprot.org/uniprotkb/F1P024" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "F1P024", "url": "https://www.uniprot.org/uniprotkb/F1P024" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "chromatin remodeling", "id": "GO:0006338", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006338", "evidence": [ { "database": "UniProtKB", "id": "F1P024", "url": "https://www.uniprot.org/uniprotkb/F1P024" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "F1P024", "url": "https://www.uniprot.org/uniprotkb/F1P024" } ], "pmid": "" }, { "name": "chromatin organization", "id": "GO:0006325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006325", "evidence": [ { "database": "UniProtKB", "id": "F1P024", "url": "https://www.uniprot.org/uniprotkb/F1P024" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "F1P024", "url": "https://www.uniprot.org/uniprotkb/F1P024" } ], "pmid": "" }, { "name": "sequence-specific DNA binding", "id": "GO:0043565", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043565", "evidence": [ { "database": "UniProtKB", "id": "F1P024", "url": "https://www.uniprot.org/uniprotkb/F1P024" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 32, "end_pos": 34, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1P024-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 252, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1P024-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1P024" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 222, 239 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 32, "end_pos": 34 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1P073-1", "uniprot_ac": "F1P073", "uniprot_id": "F1P073_CHICK", "mass": { "chemical_mass": 58729.0, "monoisotopic_mass": 58729.0 }, "refseq": { "ac": "XP_422186", "name": "chloride channel CLIC-like protein 1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_422186" }, "gene_names": [ { "name": "CLCC1", "type": "recommended", "evidence": [ { "id": "F1P073", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P073" } ] }, { "name": "CLCC1", "type": "synonym", "evidence": [ { "id": "XP_422186", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_422186" } ] } ], "protein_names": [ { "name": "Chloride channel CLIC-like protein 1", "type": "recommended", "evidence": [ { "id": "F1P073", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P073/entry#names_and_taxonomy" } ] }, { "name": "chloride channel CLIC-like protein 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_422186", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_422186" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052539.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Nov 16, 2006 this sequence version replaced XP_422186.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_422186", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_422186" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1P073", "url": "https://www.uniprot.org/uniprotkb/F1P073" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CLCC1", "url": "https://www.uniprot.org/uniprotkb/F1P073", "locus": { "chromosome": "8", "start_pos": 1338782, "end_pos": 1355610, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012107", "url": "https://www.ensembl.org/id/ENSGALG00010012107" } ] } } ], "crossref": [ { "id": "F1P073", "url": "https://alphafold.ebi.ac.uk/entry/F1P073", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000002106", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000002106", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "424343", "url": "https://www.ncbi.nlm.nih.gov/gene/424343", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR009231", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009231", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:424343", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424343", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "VQDDEWI", "url": "https://omabrowser.org/oma/group/VQDDEWI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1P073", "url": "https://www.orthodb.org/?gene=F1P073", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR34093", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR34093", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR34093:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR34093:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05934", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05934", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_422186", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_422186", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1P073", "url": "https://www.uniprot.org/uniprotkb/F1P073", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1P073-1", "url": "https://www.uniprot.org/uniprotkb/F1P073-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLVLVLCAAVLAGGGAQDDDWIDPTDMLNYDAASGTMRRPYKVNYHDSEDKTVDGIISENLSSCSREVDSLQQKIAECEKRNAKSHESRSFYIFKRYLNKILNEARKLGLPEGNTDQVHYDAEIILTKQTHLEILRFLQEEAWQSGAVDDALSNILINFKHHDYNAWHWRFEDTFGIDLYNMFMILLCLVCVVVIIATELWTRIHWFVQLKRILLISFLISFAWNWLYLYKRAFAQHQAEIAKMGQFDNICAEKLDWRESLIGWLRRQWTYQDDPCQKYYETLLVNPVLLVPPTKALAITFTTFVTEPLKHVGQGIGEFIRALMKEIPLILQVPVLIMMALFILAFCYGAASSVSVIRCLMPSQKKRLPLPDSQREEIDFSQYDGSKSDGYYSQKTPSIYRGPYDRDVQMKPGSSSSSPDVLHASAEPDTQVEDAQKPEAGNRLHTEAEVSRLETSPAATLTGEKALEHEKQRTDKEQETGKNCDPNRNVEEQSCAARPAEERKSSTCESQEGD", "length": 514, "header": "tr|F1P073-1|F1P073_CHICK Isoform 1 of Chloride channel CLIC-like protein 1 OS=Gallus gallus OX=9031 GN=CLCC1 PE=1 SV=2 CANONICAL=F1P073-1" }, "isoforms": [ { "isoform_ac": "F1P073-1", "url": "https://www.uniprot.org/uniprotkb/F1P073/entry#F1P073-1", "sequence": { "sequence": "MLVLVLCAAVLAGGGAQDDDWIDPTDMLNYDAASGTMRRPYKVNYHDSEDKTVDGIISENLSSCSREVDSLQQKIAECEKRNAKSHESRSFYIFKRYLNKILNEARKLGLPEGNTDQVHYDAEIILTKQTHLEILRFLQEEAWQSGAVDDALSNILINFKHHDYNAWHWRFEDTFGIDLYNMFMILLCLVCVVVIIATELWTRIHWFVQLKRILLISFLISFAWNWLYLYKRAFAQHQAEIAKMGQFDNICAEKLDWRESLIGWLRRQWTYQDDPCQKYYETLLVNPVLLVPPTKALAITFTTFVTEPLKHVGQGIGEFIRALMKEIPLILQVPVLIMMALFILAFCYGAASSVSVIRCLMPSQKKRLPLPDSQREEIDFSQYDGSKSDGYYSQKTPSIYRGPYDRDVQMKPGSSSSSPDVLHASAEPDTQVEDAQKPEAGNRLHTEAEVSRLETSPAATLTGEKALEHEKQRTDKEQETGKNCDPNRNVEEQSCAARPAEERKSSTCESQEGD", "length": 514, "header": "tr|F1P073-1|F1P073_CHICK Isoform 1 of Chloride channel CLIC-like protein 1 OS=Gallus gallus OX=9031 GN=CLCC1 PE=1 SV=2 CANONICAL=F1P073-1" }, "locus": { "chromosome": "8", "start_pos": 1355284, "end_pos": 1346493, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029019.1", "url": "https://www.ensembl.org/id/ENSGALT00010029019.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016778.1", "url": "https://www.ensembl.org/id/ENSGALP00010016778.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:424343", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424343", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A9J7FA35-1", "protein_name": "Chloride channel CLIC-like protein 1", "gene_name": "Clcc1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSRRWIPAQAYGAGGLAVLRVRAGRGGLAVFRMLCWLLLCGCLFLMTGHAHDDDWIDPTDMLNYDAASGTMRKSQVKYCTSERKEMSPDLTNAEELSDCLNKLDSLTHKVDDCERKKMKDYESQSNSVFRRYLNKILIEAGKLGLPDENKVDMRYDAEILLTRQTLLEIEKFLSGEEWKSGALDDALSDILINFKWHDSEAWKWRFEDSFGVDPYNAFVVLLCLLCIVLLVTTELWTIVRWYTQLKRIFIISFLFSLGWNWIYLYKVAFAQHQAGIAKMATQTDSVCVEKMDWTGSLWEWFRSSWTYEDDPCQKYYELLLVNPIWFVPPTKALAITFTNFVTEPLKHIGKATGEFIEALMKEIPVLLQIPVLVIMALAVLSFCYGAGMSVPMLRYVGGPEREPPRALEPGDRRWQKELDCRLCGGAGDADFSYMGQAGSIEQGPYDKTHACKRDVLRQRDVDARFHTGNKSPEVLRAFDLPDTEAQEHPEVVPSHKSSSMNTNLKEIGELPGESTPTEHSSSATAVSGQAAGTAEGSPIKKVPLKLDSECSLQGGTTHSPGAAVCGTDPVSSPCG", "length": 575 }, "evidence": [ { "id": "F1P073", "url": "https://omabrowser.org/oma/group/F1P073/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q1LZF8-1", "protein_name": "Chloride channel CLIC-like protein 1", "gene_name": "CLCC1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MLYSLLLCECLWLITAYAHDDEWIDPTDMLNYDAASGRMRKSQVKYGISEKEEVNPDLSCANELSECYNRLDSLTYKIDECEKQKRKDYESQSNPVFRRYLNKILIETKKLGLPDENKHDMHYDAEIILKRQTLLEIQKFLSGEDWKPGALDDALSDILINFKFHDFETWKWRFEEFFGVDPYNVFMVLLCLLCIVALVATELWTYVRWYTQLKRVFFISFLISLGWNWMYLYKLAFAQHQAEVAKMEPLNNVCAEKMNWSGSLWEWLRSSWTYKDDPCQKYYELLLVNPIWLVPPTKALAVTFTNFVTEPLKHVGKGAGEFIKALMKEIPVLLHIPVLIIMALAVLSFCYGAGKSVNMLRHVGGPEREAPQALQAGERRRQQKIDYRPHGGAGDADFYYRGQISPIEQGPNDNTYEGRRDVLRERDVGLRFQTGNKSPEVLRPFDLQEAEAREHPKVVPGLKSPNLESKPREMGEIPGESTPTESSTESSQPAKPVSGQKVSEGVEGCPAVEKAQLRTDAAGGPEEGSTCSPASTAVEVCG", "length": 542 }, "evidence": [ { "id": "F1P073", "url": "https://omabrowser.org/oma/group/F1P073/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q96S66-1", "protein_name": "Chloride channel CLIC-like protein 1", "gene_name": "CLCC1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLCSLLLCECLLLVAGYAHDDDWIDPTDMLNYDAASGTMRKSQAKYGISGEKDVSPDLSCADEISECYHKLDSLTYKIDECEKKKREDYESQSNPVFRRYLNKILIEAGKLGLPDENKGDMHYDAEIILKRETLLEIQKFLNGEDWKPGALDDALSDILINFKFHDFETWKWRFEDSFGVDPYNVLMVLLCLLCIVVLVATELWTYVRWYTQLRRVLIISFLFSLGWNWMYLYKLAFAQHQAEVAKMEPLNNVCAKKMDWTGSIWEWFRSSWTYKDDPCQKYYELLLVNPIWLVPPTKALAVTFTTFVTEPLKHIGKGTGEFIKALMKEIPALLHLPVLIIMALAILSFCYGAGKSVHVLRHIGGPESEPPQALRPRDRRRQEEIDYRPDGGAGDADFHYRGQMGPTEQGPYAKTYEGRREILRERDVDLRFQTGNKSPEVLRAFDVPDAEAREHPTVVPSHKSPVLDTKPKETGGILGEGTPKESSTESSQSAKPVSGQDTSGNTEGSPAAEKAQLKSEAAGSPDQGSTYSPARGVAGPRGQDPVSSPCG", "length": 551 }, "evidence": [ { "id": "F1P073", "url": "https://omabrowser.org/oma/group/F1P073/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q99LI2-1", "protein_name": "Chloride channel CLIC-like protein 1", "gene_name": "Clcc1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLCRLLLCECLLLITGYAHDDDWIDPTDMLNYDAASGTMRKSQVRSGTSEKKEVSPDSSEAEELSDCLHRLDSLTHKVDSCEKKKMKDYESQSNPVFRRYLNKILIEAGKLGLPDENKVEMRYDAEILLSRQTLLEIQKFLSGEEWKPGALDDALSDILINFKCHDSEAWKWQFEDYFGVDPYNVFMVLLCLLCLVVLVATELWTYVRWYTQMKRIFIISFLLSLAWNWIYLYKMAFAQHQANIAGMEPFDNLCAKKMDWTGSLWEWFTSSWTYKDDPCQKYYELLIVNPIWLVPPTKALAITFTNFVTEPLKHIGKGAGEFIKALMKEIPVLLQIPVLAILALAVLSFCYGAGRSVPMLRHFGGPDREPPRALEPDDRRRQKGLDYRLHGGAGDADFSYRGPAGSIEQGPYDKMHASKRDALRQRFHSGNKSPEVLRAFDLPDTEAQEHPEVVPSHKSPIMNTNLETGELPGESTPTEYSQSAKDVSGQVPSAGKSSPTVDKAQLKTDSECSPPGGCPPSKEAAVAAHGTEPVSSPCG", "length": 539 }, "evidence": [ { "id": "F1P073", "url": "https://omabrowser.org/oma/group/F1P073/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9WU61-1", "protein_name": "Chloride channel CLIC-like protein 1", "gene_name": "Clcc1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLCSLLLCGCLLLITGYAHDDDWIDPTDMLNYDAASGTMRKSQAKYGTSEKKEVNPGLSDAQELSDCLQRLDSLTHKVDDCEKKKMKDYESQSNPVFRRYLNKILIEAGKLGLPDEDRVDVRYDAEILLTRQTLLEIQKFLSGEEWKPGALDDALSDILTNFKSHDAEAWKWQFEDYFGVDPYNVFMVLLCLLCIVALVATELWTYVRWHTQLKRVCIISFLVSLGWNWIYLYKVAFAQHQANVAKMAPLNDVCAKKMDWTENLWEWFRISWTYKDDPCQKYYELLIVNPIWLVPPTKALAVTFTNFVTEPLKYIGKGTGEFIKALMKEIPVLLQIPVLVILALAVLGFCYGAGQSVPMLRHFRGPEREPPRALEPDDRRRQKELDYRFHGGAGDADFSYRGPAGSIEQGPYDKMHVCERDVLRQRQVNMRFPSGNKSPEVLRAFDLPDTEAQEHPEVVPSHKPSIVNTSLKETSELPRESTLAECSQCAKDGSGQVPSTAESSPIVEKAQLKTDSECRPHSTEAAAAAARGTDPVSSPCG", "length": 541 }, "evidence": [ { "id": "F1P073", "url": "https://omabrowser.org/oma/group/F1P073/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "F1P073", "url": "https://www.uniprot.org/uniprotkb/F1P073" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "F1P073", "url": "https://www.uniprot.org/uniprotkb/F1P073" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "F1P073", "url": "https://www.uniprot.org/uniprotkb/F1P073" } ], "pmid": "" }, { "name": "mitochondria-associated endoplasmic reticulum membrane contact site", "id": "GO:0044233", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044233", "evidence": [ { "database": "UniProtKB", "id": "F1P073", "url": "https://www.uniprot.org/uniprotkb/F1P073" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "chloride channel activity", "id": "GO:0005254", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005254", "evidence": [ { "database": "UniProtKB", "id": "F1P073", "url": "https://www.uniprot.org/uniprotkb/F1P073" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "endoplasmic reticulum calcium ion homeostasis", "id": "GO:0032469", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032469", "evidence": [ { "database": "UniProtKB", "id": "F1P073", "url": "https://www.uniprot.org/uniprotkb/F1P073" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 60, "end_pos": 62, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1P073-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 514, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1P073-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1P073" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 60, "end_pos": 62 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1P077-1", "uniprot_ac": "F1P077", "uniprot_id": "F1P077_CHICK", "mass": { "chemical_mass": 55779.0, "monoisotopic_mass": 55779.0 }, "refseq": { "ac": "NP_001034359", "name": "dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase precursor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001034359" }, "gene_names": [ { "name": "ALG12", "type": "recommended", "evidence": [ { "id": "F1P077", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P077" } ] }, { "name": "6-mannosyltransferase)", "type": "synonym", "evidence": [ { "id": "NP_001034359", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001034359" } ] }, { "name": "ALG12", "type": "synonym", "evidence": [ { "id": "NP_001034359", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001034359" } ] }, { "name": "alpha-1", "type": "synonym", "evidence": [ { "id": "NP_001034359", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001034359" } ] } ], "protein_names": [ { "name": "Mannosyltransferase", "type": "recommended", "evidence": [ { "id": "F1P077", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P077/entry#names_and_taxonomy" } ] }, { "name": "2.4.1.-", "type": "synonym", "evidence": [ { "id": "F1P077", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P077/entry#names_and_taxonomy" } ] }, { "name": "alpha-1,6-mannosyltransferase ALG12", "type": "synonym", "evidence": [ { "id": "NP_001034359", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001034359" } ] }, { "name": "asparagine-linked glycosylation 12 homolog (yeast, alpha-1,6-mannosyltransferase)", "type": "synonym", "evidence": [ { "id": "NP_001034359", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001034359" } ] }, { "name": "asparagine-linked glycosylation 12, alpha-1,6-mannosyltransferase homolog", "type": "synonym", "evidence": [ { "id": "NP_001034359", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001034359" } ] }, { "name": "dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase precursor", "type": "synonym", "evidence": [ { "id": "NP_001034359", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001034359" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: HAEK01045355.1, HAEK01019296.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA103992290, SAMEA103992323 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000012.1. On May 9, 2013 this sequence version replaced NP_001034359.1. Sequence Note: This RefSeq record was created from transcript data from different strains because no single transcript from the same strain was available for the full length of the gene. The extent of this transcript is supported by transcript alignments and orthologous data.", "evidence": [ { "database": "RefSeq", "id": "NP_001034359", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001034359" } ] }, { "annotation": "Mannosyltransferase that operates in the biosynthetic pathway of dolichol-linked oligosaccharides, the glycan precursors employed in protein asparagine (N)-glycosylation. The assembly of dolichol-linked oligosaccharides begins on the cytosolic side of the endoplasmic reticulum membrane and finishes in its lumen. The sequential addition of sugars to dolichol pyrophosphate produces dolichol-linked oligosaccharides containing fourteen sugars, including two GlcNAcs, nine mannoses and three glucoses. Once assembled, the oligosaccharide is transferred from the lipid to nascent proteins by oligosaccharyltransferases. In the lumen of the endoplasmic reticulum, adds the eighth mannose residue in an alpha-1,6 linkage onto Man(7)GlcNAc(2)-PP-dolichol to produce Man(8)GlcNAc(2)-PP-dolichol.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0XZT3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XZT3#function" }, { "database": "UniProtKB", "id": "ARBA00044721", "url": "https://www.uniprot.org/uniprotkb/ARBA00044721#function" }, { "database": "UniProtKB", "id": "A0A8V0Y1Q5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y1Q5#function" }, { "database": "UniProtKB", "id": "A0A8V0Y437", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y437#function" }, { "database": "UniProtKB", "id": "F1P077", "url": "https://www.uniprot.org/uniprotkb/F1P077#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1P077", "url": "https://www.uniprot.org/uniprotkb/F1P077" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ALG12", "url": "https://www.uniprot.org/uniprotkb/F1P077", "locus": { "chromosome": "1", "start_pos": 19055129, "end_pos": 19071118, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010009003", "url": "https://www.ensembl.org/id/ENSGALG00010009003" } ] } } ], "crossref": [ { "id": "F1P077", "url": "https://alphafold.ebi.ac.uk/entry/F1P077", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000008539", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000008539", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "417733", "url": "https://www.ncbi.nlm.nih.gov/gene/417733", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR005599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:417733", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417733", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WWVEVRM", "url": "https://omabrowser.org/oma/group/WWVEVRM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XZT3", "url": "https://www.orthodb.org/?gene=A0A8V0XZT3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y1Q5", "url": "https://www.orthodb.org/?gene=A0A8V0Y1Q5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y437", "url": "https://www.orthodb.org/?gene=A0A8V0Y437", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1P077", "url": "https://www.orthodb.org/?gene=F1P077", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22760", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22760", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22760:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22760:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03901", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03901", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:F1P077", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:F1P077", "database": "PRO", "categories": [ "Protein" ] }, { "id": "R-GGA-446193", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-446193", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001034359", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001034359", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "29535", "url": "https://www.rhea-db.org/rhea/29535", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0XZT3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XZT3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XZT3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XZT3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y1Q5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y1Q5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y1Q5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y1Q5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y437", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y437", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y437-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y437-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1P077", "url": "https://www.uniprot.org/uniprotkb/F1P077", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1P077-1", "url": "https://www.uniprot.org/uniprotkb/F1P077-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAQKRSSSGRSFPLLLLIIVVAFVHLTVCPFTKVEESFNLQAIHDVVYHQLDLDKYDHHEFPGVVPRTFLGPIFIAALSSPAIYILSLLKMSKFYSQLIVRGSLGLSVIYTLWKLQKEVRKQFGATTSTVFCLITVTQFHLMFYCTRTLPNVFALPFVLLALTFWIQQKQRPFIWFSALAIIVFRSELAIFLGLMLLVTFLTKRISVLKILSHAVPAGFFWLGLTVAVDSLFWRQLVWPEGKVLWYNTILNKSSNWGTSPFFWYFYSALPRALGCSIVFVPLGAAEKRTRILLLPALGFIFLYSFLPHKELRFIIYTFPVFNIVAAKVCSRILNNYRKSWLYKLGSLFVVMHLLVNAAYSGTSLYVSHFNYPGGVAIQKLHELVPSTAEVSVHIDVAAAQTGVSRFLEINSDWRYDKREDVKPGDQLMFSYTHILMETNPLQISHYKTTHRPLANIPGISKIGLNLTALPPFTLNLKPKLVLLEKLPLSS", "length": 490, "header": "tr|F1P077-1|F1P077_CHICK Isoform 1 of Mannosyltransferase OS=Gallus gallus OX=9031 GN=ALG12 PE=3 SV=3 CANONICAL=F1P077-1" }, "isoforms": [ { "isoform_ac": "A0A8V0XZT3-1", "url": "https://www.uniprot.org/uniprotkb/F1P077/entry#A0A8V0XZT3-1", "sequence": { "sequence": "MAQKRSSSGRSFPLLLLIIVVAFVHLTVCPFTKVEESFNLQAIHDVVYHQLDLDKYDHHEFPGVVPRTFLGPIFIAALSSPAIYILSLLKMSKFYSQLIVRGSLGLSVIYTLWKLQKEVRKQFGATTSTVFCLITVTQFHLMFYCTRTLPNVFALPFVLLALTFWIQQKQRPFIWFSALAIIVFRSELVTCFLIEALR", "length": 198, "header": "tr|A0A8V0XZT3-1|A0A8V0XZT3_CHICK Computationally mapped isoform of Mannosyltransferase OS=Gallus gallus OX=9031 GN=ALG12 PE=3 SV=1 CANONICAL=F1P077-1" }, "locus": { "chromosome": "1", "start_pos": 19065318, "end_pos": 19061561, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010021444.1", "url": "https://www.ensembl.org/id/ENSGALT00010021444.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010012218.1", "url": "https://www.ensembl.org/id/ENSGALP00010012218.1" } ] } }, { "isoform_ac": "A0A8V0Y1Q5-1", "url": "https://www.uniprot.org/uniprotkb/F1P077/entry#A0A8V0Y1Q5-1", "sequence": { "sequence": "MAQKRSSSGRSFPLLLLIIVVAFVHLTVCPFTKVEESFNLQAIHDVVYHQLDLDKYDHHEFPGVVPRTFLGPIFIAALSSPAIYILSLLKMSKFYSQLIVRGSLGLSVIYTLWKLQKEVRKQFGATTSTVFCLITVTQFHLMFYCTRTLPNVFALPFVLLALTFWIQQKQRPFIWFSALAIIVFRSELAIFLGLMLLVTFLTKRISVLKILSHAVPAGFFWLAVDSLFWRQLVWPEGKVLWYNTILNKSSNWGTSPFFWYFYSALPRALGCSIVFVPLGAAEKRTRILLLPALGFIFLYSFLPHKELRFIIYTFPVFNIVAAKVCSRILNNYRKSWLYKLGSLFVVMHLLVNAAYSGTSLYVSHFNYPGGVAIQKLHELVPSTAEVSVHIDVAAAQTGVSRFLEINSDWRYDKREDVKPGDQLMFSYTHILMETNPLQISHYKTTHRPLANIPGISKIGLNLTALPPFTLNLKPKLVLLEKLPLSS", "length": 486, "header": "tr|A0A8V0Y1Q5-1|A0A8V0Y1Q5_CHICK Computationally mapped isoform of Mannosyltransferase OS=Gallus gallus OX=9031 GN=ALG12 PE=3 SV=1 CANONICAL=F1P077-1" }, "locus": { "chromosome": "1", "start_pos": 19065318, "end_pos": 19056226, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010021498.1", "url": "https://www.ensembl.org/id/ENSGALT00010021498.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010012247.1", "url": "https://www.ensembl.org/id/ENSGALP00010012247.1" } ] } }, { "isoform_ac": "A0A8V0Y437-1", "url": "https://www.uniprot.org/uniprotkb/F1P077/entry#A0A8V0Y437-1", "sequence": { "sequence": "MAQKRSSSGRSFPLLLLIIVVAFVHLTVCPFTKVEESFNLQAIHDVVYHQLDLDKYDHHEFPGVVPRTFLGPIFIAALSSPAIYILSLLKMSKFYSQLIVRGSLGLSVIYTLWKLQKEVRKQFGATTSTVFCLITVTQFHLMFYCTRTLPNVFALPFVLLALTFWIQQKQRPFIWFSALAIIVFRSELAIFLGLMLLVTFLTKRISVLKILSHAVPAGFFWLVAVDSLFWRQLVWPEGKVLWYNTILNKSSNWGTSPFFWYFYSALPRALGCSIVFVPLGAAEKRTRILLLPALGFIFLYSFLPHKELRFIIYTFPVFNIVAAKVCSRILNNYRKSWLYKLGSLFVVMHLLVNAAYSGTSLYVSHFNYPGGVAIQKLHELVPSTAEVSVHIDVAAAQTGVSRFLEINSDWRYDKREDVKPGDQLMFSYTHILMETNPLQISHYKTTHRPLANIPGISKIGLNLTALPPFTLNLKPKLVLLEKLPLSS", "length": 487, "header": "tr|A0A8V0Y437-1|A0A8V0Y437_CHICK Computationally mapped isoform of Mannosyltransferase OS=Gallus gallus OX=9031 GN=ALG12 PE=3 SV=1 CANONICAL=F1P077-1" }, "locus": { "chromosome": "1", "start_pos": 19065318, "end_pos": 19056226, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010021486.1", "url": "https://www.ensembl.org/id/ENSGALT00010021486.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010012243.1", "url": "https://www.ensembl.org/id/ENSGALP00010012243.1" } ] } }, { "isoform_ac": "F1P077-1", "url": "https://www.uniprot.org/uniprotkb/F1P077/entry#F1P077-1", "sequence": { "sequence": "MAQKRSSSGRSFPLLLLIIVVAFVHLTVCPFTKVEESFNLQAIHDVVYHQLDLDKYDHHEFPGVVPRTFLGPIFIAALSSPAIYILSLLKMSKFYSQLIVRGSLGLSVIYTLWKLQKEVRKQFGATTSTVFCLITVTQFHLMFYCTRTLPNVFALPFVLLALTFWIQQKQRPFIWFSALAIIVFRSELAIFLGLMLLVTFLTKRISVLKILSHAVPAGFFWLGLTVAVDSLFWRQLVWPEGKVLWYNTILNKSSNWGTSPFFWYFYSALPRALGCSIVFVPLGAAEKRTRILLLPALGFIFLYSFLPHKELRFIIYTFPVFNIVAAKVCSRILNNYRKSWLYKLGSLFVVMHLLVNAAYSGTSLYVSHFNYPGGVAIQKLHELVPSTAEVSVHIDVAAAQTGVSRFLEINSDWRYDKREDVKPGDQLMFSYTHILMETNPLQISHYKTTHRPLANIPGISKIGLNLTALPPFTLNLKPKLVLLEKLPLSS", "length": 490, "header": "tr|F1P077-1|F1P077_CHICK Isoform 1 of Mannosyltransferase OS=Gallus gallus OX=9031 GN=ALG12 PE=3 SV=3 CANONICAL=F1P077-1" }, "locus": { "chromosome": "1", "start_pos": 19065318, "end_pos": 19056226, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010021475.1", "url": "https://www.ensembl.org/id/ENSGALT00010021475.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010012236.1", "url": "https://www.ensembl.org/id/ENSGALP00010012236.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "gga:417733", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417733", "resource": "KEGG Pathway" }, { "id": "R-GGA-446193", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-446193", "resource": "Reactome", "description": "Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein" } ], "orthologs": [ { "uniprot_canonical_ac": "A8MR93-1", "protein_name": "Dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase", "gene_name": "ALG12", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MPTDSKMAKFLQSYGYDLILGSVAAIYVVMAPYTKVEESFNVQSMHDILYHRHHLDSYDHLEFPGVVPRTFIGAFIVSVFASPVVSIISCLGFPKVYSLVAARLVLGCIILSTLRFFRIQIKKKFGNQVETFFVLFTSLQFHFLFYCTRPLPNILALGLVNLAYGNWLKGNFYPALSFLIFATVIFRCDTMLLLGPIGLELLLTKSISFWKALKYCVGTALLAVGLTIFVDSIMWKKFVWPEFEVFWFNSILNRSSDWGTHSIHWYFTSALPRSLLVAYPLSLLGTLVDRRVPFFIVPVLSFVILYSKLPHKELRFIISSVPMFNLSAAVAASRIYNNRKKTIWKLVNMVMLAFFAISAGCTVVTFMASYYNYPSGYALKRLHQIGHPANVAGEEWVHIDTFGAMNGISRFCEDDFPWRYSKEEEIVVEELRNRNFTYLVNEHSSVDGYKCLFYEEGFERLELRRGFPPIVLVKKAKVYLHREMKKEDPFHKKWPGC", "length": 497 }, "evidence": [ { "id": "F1P077", "url": "https://omabrowser.org/oma/group/F1P077/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "F1RXR3-1", "protein_name": "Mannosyltransferase", "gene_name": "ALG12", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MQVREAQAPMGGKRPPGPGQPRGLLGLLVAVAALHLLACPYTKVEESFNLQAVHDLLYHRLDVQQFDHLEFPGVVPRTFLGPLLLAALSSPAVCVLSLLETSKFYSQLAVRAVLGLGVIWGLWTLQTEVRRQFGAPVATLFCCLTASQFHLMFYCSRPLPNVLALPFVLLALTAWLQQKWPRFIRLSAFAILVFRAELSLLLGLALLLPLCSRRLSVARALRCAVPAGVLCLGLTVAVDSYFWRAPVWPEGKVLWYNTVLNKSSNWGTSPLLWYFYSALPRGLGCSLLFVPLGAVDRRAVALLLPALGFVALYSLLPHKELRFIIYAFPLLNVVAARGCARVLNNRRKSWLYKVGSLFVIGHLVANAMCSATGLYVSHFNYPGGVALQRLHELVPPRTDVSVHIGVAAAQTGVSRFLEVNSAWRYEKTEDLQPGSERMLAYTHLLVEAAPGHLTPYRDTHRVLASVPGTTGLSLNLSRLPPFDVNLQTKLVLLERLVGPS", "length": 500 }, "evidence": [ { "id": "F1P077", "url": "https://omabrowser.org/oma/group/F1P077/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P53730-1", "protein_name": "Dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase", "gene_name": "ALG12", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MRWSVLDTVLLTVISFHLIQAPFTKVEESFNIQAIHDILTYSVFDISQYDHLKFPGVVPRTFVGAVIIAMLSRPYLYLSSLIQTSRPTSIDVQLVVRGIVGLTNGLSFIYLKNCLQDMFDEITEKKKEENEDKDIYIYDSAGTWFLLFLIGSFHLMFYSTRTLPNFVMTLPLTNVALGWVLLGRYNAAIFLSALVAIVFRLEVSALSAGIALFSVIFKKISLFDAIKFGIFGLGLGSAISITVDSYFWQEWCLPEVDGFLFNVVAGYASKWGVEPVTAYFTHYLRMMFMPPTVLLLNYFGYKLAPAKLKIVSLASLFHIIVLSFQPHKEWRFIIYAVPSIMLLGATGAAHLWENMKVKKITNVLCLAILPLSIMTSFFISMAFLYISRMNYPGGEALTSFNDMIVEKNITNATVHISIPPCMTGVTLFGELNYGVYGINYDKTENTTLLQEMWPSFDFLITHEPTASQLPFENKTTNHWELVNTTKMFTGFDPTYIKNFVFQERVNVLSLLKQIIFDKTPTVFLKELTANSIVKSDVFFTYKRIKQDEKTD", "length": 551 }, "evidence": [ { "id": "F1P077", "url": "https://omabrowser.org/oma/group/F1P077/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q55FZ9-1", "protein_name": "Mannosyltransferase", "gene_name": "alg12", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIRNRKPITNNNSNNSNNNNNNGKIKRRERILNRQKEQIEQFYTDFIIFVVMFIHVVVCPFTKVEESFNLQGMHDIINIGNKGSDERGVSFEYDHLEFPGVIPRTFIGSLFISSLSYLPLNIFFGSSATEFISKLFDNQFSGTTKMVQLYFVRLMLGTISCISIMIFKRSISKRFGNQVAFWFTLITVSQFHLMFYISRPLPNIFALILVIIGYSFWLNDDGNGNGNGSIDWMIMVLTIAIFIFRSEILILAGPIVLSCLFLQKNLKFHRFLIIGIFTALISIIFTVFIDSYFWRRILYPELEVFQFNTIENKSSEWGTLPFHWYFSTALPKTLAFTLLFFFIGLISKYNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNKSTPITFLLPILLFIGIYSILPHKEIRFIFYSIPIINLISAIGATKLWNYGKSRKNQLFKLLISLFTIGILIGNSMISLFSLYASSLNYPGGHSMISLHKHLNLTDEMGLLLLLPPHTNADVDGDDENQGIIDCKVHIDNMAAISGVSRFGELNDFCVYSKKERDVNFNDFNYLIAPNTSTTQLGFKEVDSISAFDHIKLKKTFPFFEIVESPTLYIMEKINK", "length": 646 }, "evidence": [ { "id": "F1P077", "url": "https://omabrowser.org/oma/group/F1P077/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q8VDB2-1", "protein_name": "Dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase", "gene_name": "Alg12", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAGKKSSGKRSWPLLGLLVTVATIHLVICPYTKVEESFNLQATHDLLYHQLDIDKYDHHEFPGVVPRTFLGPLVIAAFSSPVVYVLSLLEVSKFYSQLIVRGVLGLGVISGLWTLQKEVRQQFGATVAVMFCWISATQFHLMFYCTRTLPNVLALAVVLPALTAWLQRRWALFVWLSAFVIIGFRAELAMLLGIALLLTLYQRRLTVARVLRHAIPAGLLCLGLTVAVDSYFWRYLVWPEGVVLWYNTVLNKSSNWGTSPLLWYFYSALPRGLGCSLLFIPLGAVDRRTYALALPSLGFVALYSLLPHKELRFIIYTFPVLNIMAARGCTYILNKKSWPYKVRAMLVTGHILVNVAYTATSLYVSHFNYPGGVAMQQLHELVPPQTDVLLHIDVAAAQTGVSRFLQVNDDWRYDKSEDVGAAAMLNYTHILMEAVPGHPALYRDTHRVLASIEGTTGISLNLMKLPPFDVNLQTKLVLLERLLRPA", "length": 486 }, "evidence": [ { "id": "F1P077", "url": "https://omabrowser.org/oma/group/F1P077/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9BV10-1", "protein_name": "Dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase", "gene_name": "ALG12", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAGKGSSGRRPLLLGLLVAVATVHLVICPYTKVEESFNLQATHDLLYHWQDLEQYDHLEFPGVVPRTFLGPVVIAVFSSPAVYVLSLLEMSKFYSQLIVRGVLGLGVIFGLWTLQKEVRRHFGAMVATMFCWVTAMQFHLMFYCTRTLPNVLALPVVLLALAAWLRHEWARFIWLSAFAIIVFRVELCLFLGLLLLLALGNRKVSVVRALRHAVPAGILCLGLTVAVDSYFWRQLTWPEGKVLWYNTVLNKSSNWGTSPLLWYFYSALPRGLGCSLLFIPLGLVDRRTHAPTVLALGFMALYSLLPHKELRFIIYAFPMLNITAARGCSYLLNNYKKSWLYKAGSLLVIGHLVVNAAYSATALYVSHFNYPGGVAMQRLHQLVPPQTDVLLHIDVAAAQTGVSRFLQVNSAWRYDKREDVQPGTGMLAYTHILMEAAPGLLALYRDTHRVLASVVGTTGVSLNLTQLPPFNVHLQTKLVLLERLPRPS", "length": 488 }, "evidence": [ { "id": "F1P077", "url": "https://omabrowser.org/oma/group/F1P077/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "F1P077", "url": "https://www.uniprot.org/uniprotkb/F1P077" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "protein N-linked glycosylation", "id": "GO:0006487", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006487", "evidence": [ { "database": "UniProtKB", "id": "F1P077", "url": "https://www.uniprot.org/uniprotkb/F1P077" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "alpha-1,6-mannosyltransferase activity", "id": "GO:0000009", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000009", "evidence": [ { "database": "UniProtKB", "id": "F1P077", "url": "https://www.uniprot.org/uniprotkb/F1P077" } ], "pmid": "" }, { "name": "dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase activity", "id": "GO:0052917", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0052917", "evidence": [ { "database": "UniProtKB", "id": "F1P077", "url": "https://www.uniprot.org/uniprotkb/F1P077" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 251, "end_pos": 253, "annotation": "n_glycosylation_sequon" }, { "start_pos": 465, "end_pos": 467, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "29535", "name": "", "equation": "an alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc-diphospho-di-trans,poly-cis-dolichol + a di-trans,poly-cis-dolichyl beta-D-mannosyl phosphate = an alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc-diphospho-di-trans,poly-cis-dolichol + a di-trans,poly-cis-dolichyl phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1P077-1" ], "evidence": [ { "id": "29535", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/29535" } ] }, { "id": "R-GGA-446198", "name": "ALG12 transfers Man to N-glycan precursor (GlcNAc)2 (Man)7 (PP-Dol)1", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "endoplasmic reticulum lumen", "input_participant_list": [ "R-ALL-449312" ], "output_participant_list": [ "R-ALL-449311", "R-ALL-449365" ], "enzyme_list": [ "F1P077-1" ], "evidence": [ { "id": "R-GGA-446198", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-446198" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-449311", "participant_name": "DOLP [lumenal side of endoplasmic reticulum membrane]", "crossref": [ { "id": "ZINC000030320683", "database": "ZINC", "url": "" }, { "id": "ZINC000030320680", "database": "ZINC", "url": "" }, { "id": "57683", "database": "ChEBI", "url": "" } ] }, { "participant_id": "R-ALL-449312", "participant_name": "(GlcNAc)2 (Man)7 (PP-Dol)1 [lumenal side of endoplasmic reticulum membrane]", "crossref": [ { "id": "59088", "database": "ChEBI", "url": "" } ] }, { "participant_id": "R-ALL-449365", "participant_name": "(GlcNAc)2 (Man)8 (PP-Dol)1 [lumenal side of endoplasmic reticulum membrane]", "crossref": [ { "id": "59091", "database": "ChEBI", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "F1P077", "gene_name": "ALG12", "activity": [ { "ec_number": "2.4.1.-", "activity": "", "evidence": [ { "id": "F1P077", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P077" } ] } ] } ], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1P077-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 490, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1P077-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1P077" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 251, "end_pos": 253 }, { "start_pos": 465, "end_pos": 467 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1P0A7-1", "uniprot_ac": "F1P0A7", "uniprot_id": "F1P0A7_CHICK", "mass": { "chemical_mass": 86108.0, "monoisotopic_mass": 86108.0 }, "refseq": { "ac": "NP_001006317", "name": "amyloid beta precursor like protein 2 precursor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006317" }, "gene_names": [ { "name": "APLP2", "type": "recommended", "evidence": [ { "id": "F1P0A7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P0A7" } ] }, { "name": "APLP2", "type": "synonym", "evidence": [ { "id": "NP_001006317", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006317" } ] } ], "protein_names": [ { "name": "Amyloid beta like protein 2", "type": "synonym", "evidence": [ { "id": "F1P0A7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P0A7/entry#names_and_taxonomy" } ] }, { "name": "amyloid beta (A4) precursor-like protein 2", "type": "synonym", "evidence": [ { "id": "NP_001006317", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006317" } ] }, { "name": "amyloid beta precursor like protein 2 precursor", "type": "synonym", "evidence": [ { "id": "NP_001006317", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006317" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: SRR13267659.256455.1, SRR13267658.5754.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA103992290, SAMEA103992323 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000341.1. On Oct 23, 2010 this sequence version replaced NP_001006317.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001006317", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006317" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1P0A7", "url": "https://www.uniprot.org/uniprotkb/F1P0A7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "APLP2", "url": "https://www.uniprot.org/uniprotkb/F1P0A7", "locus": { "chromosome": "24", "start_pos": 1495545, "end_pos": 1536733, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010023571", "url": "https://www.ensembl.org/id/ENSGALG00010023571" } ] } } ], "crossref": [ { "id": "F1P0A7", "url": "https://alphafold.ebi.ac.uk/entry/F1P0A7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000001250", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000001250", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd21709", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd21709", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd22607", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22607", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "419727", "url": "https://www.ncbi.nlm.nih.gov/gene/419727", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002223", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002223", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008154", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008154", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008155", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008155", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011178", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011178", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015849", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015849", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019543", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019543", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019744", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019744", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019745", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019745", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020901", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020901", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024329", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024329", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036176", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036176", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036454", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036454", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036669", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036669", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036880", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036880", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:419727", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419727", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PYRILHA", "url": "https://omabrowser.org/oma/group/PYRILHA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZWX1", "url": "https://www.orthodb.org/?gene=A0A8V0ZWX1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A108", "url": "https://www.orthodb.org/?gene=A0A8V1A108", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1P0A7", "url": "https://www.orthodb.org/?gene=F1P0A7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23103", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23103", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23103:SF14", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23103:SF14", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00014", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00014", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02177", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02177", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF10515", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10515", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12924", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12924", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12925", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12925", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-114608", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-114608", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-381426", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-381426", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-8957275", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8957275", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001006317", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006317", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZWX1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWX1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZWX1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWX1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A108", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A108", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A108-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A108-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1P0A7", "url": "https://www.uniprot.org/uniprotkb/F1P0A7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1P0A7-1", "url": "https://www.uniprot.org/uniprotkb/F1P0A7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGTARHFPLLLLLGLAGPAVTLAGYIEALAANAGTGFAVAEPQIAMFCGKLNMHVNIQTGKWEPDTSGTKSCFGTKEEILQYCQEMYPDLQITNVVEANQPVSIDSWCKRGKKQCKDHTHIVVPYKCLVGEFVSDVLLVPEKCRFFHKERMDVCESHQHWHTAAKEACLTEGMILHSYGMLLPCGVDQFHGTEYVCCPQTKVVDEALSKEEEDEDEDEDYDTYKSEFPTEAGVEDFTGTAVEEDEDEEDEGEEEEDVVEDRDYYYNSYKVDDYDEETTTEPTSDKAVSEKEVSSDMKSVCSQEAMTGPCRAVMPRWYFDSNKRKCIRFIYGGCGGNRNNFESEEYCMAVCKKMMPTDDVDVYFETPADDNEHARFQKAKEQLEVRHHNRMDRVKKEWEEAEHQAVNLPKAERQTLIQHFQAMVKSLEKEAASEKQQLVETHLARVEAILNDRRRIALENYLAALQAVPPRPHRIVQALKRYVRAENKDRLHTIRHYQHVLAVDPEKAAQMKSQVMTHLRVIEERMNQSLSLLYKVPYVAEEIQDEIDELLQEQRADMDQFTSSISESQVDVRVSSEESEEIHLEGKPFRPFQVKTFPAVPENEDPQPDLYHPMKKGSGMTELDRLSDTEEKVINSKKKVDENVVIDETLDVKEMIFNAERVGGLVDEPDNDNSLRDDFSFSSSALIGLLVIAVAIATVIVISLVMLRKRQYGTISHGIVEVDPMLTPEERHLSKMQNHGYENPTYKYLEQMQI", "length": 753, "header": "tr|F1P0A7-1|F1P0A7_CHICK Isoform 1 of Amyloid beta like protein 2 OS=Gallus gallus OX=9031 GN=APLP2 PE=1 SV=3 CANONICAL=F1P0A7-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZWX1-1", "url": "https://www.uniprot.org/uniprotkb/F1P0A7/entry#A0A8V0ZWX1-1", "sequence": { "sequence": "MGTARHFPLLLLLGLAGPAVTLAGYIEALAANAGTGFAVAEPQIAMFCGKLNMHVNIQTGKWEPDTSGTKSCFGTKEEILQYCQEMYPDLQITNVVEANQPVSIDSWCKRGKKQCKDHTHIVVPYKCLVGEFVSDVLLVPEKCRFFHKERMDVCESHQHWHTAAKEACLTEGMILHSYGMLLPCGVDQFHGTEYVCCPQTKVVDEALSKEEEDEDEDEDYDTYKSEFPTEAGVEDFTGTAVEEDEDEEDEGEEEEDVVEDRDYYYNSYKVDDYDEETTTEPTSDKAVSEKEVSSDMKLPTDDVDVYFETPADDNEHARFQKAKEQLEVRHHNRMDRVKKEWEEAEHQAVNLPKAERQTLIQHFQAMVKSLEKEAASEKQQLVETHLARVEAILNDRRRIALENYLAALQAVPPRPHRIVQALKRYVRAENKDRLHTIRHYQHVLAVDPEKAAQMKSQVMTHLRVIEERMNQSLSLLYKVPYVAEEIQDEIDELLQEQRADMDQFTSSISESQVDVRVSSEESEEIHLEGKPFRPFQVKTFPAVPENEDPQPDLYHPMKKGSGMTELDRLSDTEEKVINSKKKVDENVVIDETLDVKEMIFNAERVGGLVDEPDNDNSLRDDFSFSSSALIGLLVIAVAIATVIVISLVMLRKRQYGTISHGIVEVDPMLTPEERHLSKMQNHGYENPTYKYLEQMQI", "length": 697, "header": "tr|A0A8V0ZWX1-1|A0A8V0ZWX1_CHICK Computationally mapped isoform of Amyloid beta like protein 2 OS=Gallus gallus OX=9031 GN=APLP2 PE=1 SV=1 CANONICAL=F1P0A7-1" }, "locus": { "chromosome": "24", "start_pos": 1536691, "end_pos": 1497006, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010057377.1", "url": "https://www.ensembl.org/id/ENSGALT00010057377.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034871.1", "url": "https://www.ensembl.org/id/ENSGALP00010034871.1" } ] } }, { "isoform_ac": "A0A8V1A108-1", "url": "https://www.uniprot.org/uniprotkb/F1P0A7/entry#A0A8V1A108-1", "sequence": { "sequence": "MGTARHFPLLLLLGLAGPAVTLAGYIEALAANAGTGFAVAEPQIAMFCGKLNMHVNIQTGKWEPDTSGTKSCFGTKEEILQYCQEMYPDLQITNVVEANQPVSIDSWCKRGKKQCKDHTHIVVPYKCLVGEFVSDVLLVPEKCRFFHKERMDVCESHQHWHTAAKEACLTEGMILHSYGMLLPCGVDQFHGTEYVCCPQTKVVDEALSKEEEDEDEDEDYDTYKSEFPTEAGVEDFTGTAVEEDEDEEDEGEEEEDVVEDRDYYYNSYKVDDYDEETTTEPTSDKAVSEKEVSSDMKSVCSQEAMTGPCRAVMPRWYFDSNKRKCIRFIYGGCGGNRNNFESEEYCMAVCKKMMPTDDVDVYFETPADDNEHARFQKAKEQLEVRHHNRMDRVKKEWEEAEHQAVNLPKAERQTLIQHFQAMVKSLEKEAASEKQQLVETHLARVEAILNDRRRIALENYLAALQAVPPRPHRIVQALKRYVRAENKDRLHTIRHYQHVLAVDPEKAAQMKSQVMTHLRVIEERMNQSLSLLYKVPYVAEEIQDEIDELLQEQRADMDQFTSSISESQVDVRVSSEESEEIHLEGKPFRPFQVKTFPAVPENEGSGMTELDRLSDTEEKVINSKKKVDENVVIDETLDVKEMIFNAERVGGLVDEPDNDNSLRDDFSFSSSALIGLLVIAVAIATVIVISLVMLRKRQYGTISHGIVEVDPMLTPEERHLSKMQNHGYENPTYKYLEQMQI", "length": 741, "header": "tr|A0A8V1A108-1|A0A8V1A108_CHICK Computationally mapped isoform of Amyloid beta like protein 2 OS=Gallus gallus OX=9031 GN=APLP2 PE=1 SV=1 CANONICAL=F1P0A7-1" }, "locus": { "chromosome": "24", "start_pos": 1536691, "end_pos": 1497006, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010057386.1", "url": "https://www.ensembl.org/id/ENSGALT00010057386.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034874.1", "url": "https://www.ensembl.org/id/ENSGALP00010034874.1" } ] } }, { "isoform_ac": "F1P0A7-1", "url": "https://www.uniprot.org/uniprotkb/F1P0A7/entry#F1P0A7-1", "sequence": { "sequence": "MGTARHFPLLLLLGLAGPAVTLAGYIEALAANAGTGFAVAEPQIAMFCGKLNMHVNIQTGKWEPDTSGTKSCFGTKEEILQYCQEMYPDLQITNVVEANQPVSIDSWCKRGKKQCKDHTHIVVPYKCLVGEFVSDVLLVPEKCRFFHKERMDVCESHQHWHTAAKEACLTEGMILHSYGMLLPCGVDQFHGTEYVCCPQTKVVDEALSKEEEDEDEDEDYDTYKSEFPTEAGVEDFTGTAVEEDEDEEDEGEEEEDVVEDRDYYYNSYKVDDYDEETTTEPTSDKAVSEKEVSSDMKSVCSQEAMTGPCRAVMPRWYFDSNKRKCIRFIYGGCGGNRNNFESEEYCMAVCKKMMPTDDVDVYFETPADDNEHARFQKAKEQLEVRHHNRMDRVKKEWEEAEHQAVNLPKAERQTLIQHFQAMVKSLEKEAASEKQQLVETHLARVEAILNDRRRIALENYLAALQAVPPRPHRIVQALKRYVRAENKDRLHTIRHYQHVLAVDPEKAAQMKSQVMTHLRVIEERMNQSLSLLYKVPYVAEEIQDEIDELLQEQRADMDQFTSSISESQVDVRVSSEESEEIHLEGKPFRPFQVKTFPAVPENEDPQPDLYHPMKKGSGMTELDRLSDTEEKVINSKKKVDENVVIDETLDVKEMIFNAERVGGLVDEPDNDNSLRDDFSFSSSALIGLLVIAVAIATVIVISLVMLRKRQYGTISHGIVEVDPMLTPEERHLSKMQNHGYENPTYKYLEQMQI", "length": 753, "header": "tr|F1P0A7-1|F1P0A7_CHICK Isoform 1 of Amyloid beta like protein 2 OS=Gallus gallus OX=9031 GN=APLP2 PE=1 SV=3 CANONICAL=F1P0A7-1" }, "locus": { "chromosome": "24", "start_pos": 1536691, "end_pos": 1497006, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010057403.1", "url": "https://www.ensembl.org/id/ENSGALT00010057403.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034882.1", "url": "https://www.ensembl.org/id/ENSGALP00010034882.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:419727", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419727", "resource": "KEGG Pathway" }, { "id": "R-GGA-114608", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-114608", "resource": "Reactome", "description": "Platelet degranulation" }, { "id": "R-GGA-381426", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-381426", "resource": "Reactome", "description": "Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)" }, { "id": "R-GGA-8957275", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8957275", "resource": "Reactome", "description": "Post-translational protein phosphorylation" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287A5V7-1", "protein_name": "Amyloid beta precursor like protein 2", "gene_name": "APLP2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAATRTAAAAATGKFLLLLLLGLSAPAAALAGYIEALAANAGTGFAVAEPQIAMFCGKLNMHVNIQTGKWEPDPTGTKSCFGTKEEVLQYCQEMYPELQITNVMEANQPVRVDNWCRRDKKQCKSHVVIPSKCLVGEFVSDVLLVPEKCQFFHKERMEVCENHQHWHTVVKEACLTQGMTLYSYGMLLPCGVDQFHGTEYVCCPQTKLVRSSVSKEEEEDDDDDEEDDDDEENEEEDEEEDYDIYKSEFPTEADLEDFTEAAVDEDEEDEEGEEVVEDRDYYYDTFKGDEYNEEGPTEPSRDRAAAERVTHDVRAVCSQEALTGPCRAVMPRWYFDLSKGKCVRFIYGGCGGNRNNFESEDYCMAVCKAMIPPTPLPTNDVDVYFETSADDNEHARFQKAKEQLEIRHRNRMDRVKKEWEEAELQAKNLPKAERQTLIQHFQAMVKALEKEAASEKQQLVETHLARVEAMLNDRRRVALENYLAALQADPPRPHRILQALRRYVRAENKDRLHTIRHYQHVLAVDPEKAAQMKSQVMTHLHVIEERRNQSLSLLYKVPYVAQEIQEEIDELLQEQRADMDQFTASISETPVDVRVSSEESDEMPPLYPLHPFPSLPENEDPQPELYHPVKKGSALGEQDGGLIGAEEKVINSKKKVDENMVIDETLDVKEMIFNAERVGGLEEAPESTGPLREDFGLSSSALIGLLVIAVAIATVIVISLVMLRKRQYGTISHGIVEVDPMLTPEERHLNKMQNHGYENPTYKYLEQMQI", "length": 770 }, "evidence": [ { "id": "F1P0A7", "url": "https://omabrowser.org/oma/group/F1P0A7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A2R8Q4V0-1", "protein_name": "Amyloid beta precursor like protein 2 isoform X1", "gene_name": "aplp2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MGSVPAVSVLILAIAVPSLAGYIEALAANAGTGFAVAEPQVAMFCGKLNMHINIQTGRWEPDPSGSKTCVGTKEGVLQYCQEIYPELQITNVVEANQPVKIENWCKKDKKQCKGHAHIVVPYKCLVGEFVSDVLLVPEKCKFFHKERMDMCVSHQQWHGVAKEACSKGNMVLHSYGMLLPCGIDKFHGTEYVCCPSTRPEEPAPPASPSKEMDDEDDDDEEEEDVEEPVVEEDEEDDEDAVDESEPVAIDPPTQEDTAEEEEEQEEDGDEEDYHYIYEDEEEDRDSEEKDVKKEKAVMPEKQDDDKTLQEVEAVCSLEAETGPCRASMPRWHFDMQQRKCVRFIYGGCAGNRNNFDSEEYCMVVCKRLTVPPTPQPTDDVDVYFETPADDKEHSRFQKAKEQLEIRHRNRMERVRKEWEEAESQARNLPKAERQTLIQHFQAMVESLEEEAASEKQQLVETHLARVEAMLNDRRRLALENYLAALQADPPRPHRILQALKRYVRAENKDRQHTIRHYQHVLAVDPEKAAQMKSQVMTHLRVIEERMNQSLSLLYKVPYVAEEIQDEIDELLQVQKADMDQFLSSISESQPDVTVSSEESVEVPAFEGKPFRPFQVNSLGSPAEPEGDLSEPPRAFKKGSGMNSLDGLIGAEEKVINSKNKINENVVIDETLDVKEVILNGVDPLFSRGSEQESFRPLVDDFSFGSSALIGLLVIAVAIATVIVISLVLLRKRQYGTISHGIVEVDPMLTPEERHLSKMQNHGYENPTYKYLEQMQI", "length": 776 }, "evidence": [ { "id": "F1P0A7", "url": "https://omabrowser.org/oma/group/F1P0A7/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "P15943-1", "protein_name": "Amyloid beta precursor like protein 2", "gene_name": "Aplp2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAATGTAAAAATGKLLVLLLLGLTAPAAALAGYIEALAANAGTGFAVAEPQIAMFCGKLNMHVNIQTGKWEPDPTGTKSCLGTKEEVLQYCQEIYPELQITNVMEANQPVNIDSWCRRDKKQCRSHIVIPFKCLVGEFVSDVLLVPENCQFFHQERMEVCEKHQRWHTVVKEACLTEGMTLYSYGMLLPCGVDQFHGTEYVCCPQTKVVDSDSTMSKEEEEEEEEDEEEDYALDKSEFPTEADLEDFTEAAADEDEDEEEEEEEEGEEVVEDRDYYYDSFKGDDYNEENPTEPSSDGTISDKEIAHDVKAVCSQEAMTGPCRAVMPRWYFDLSKGKCVRFIYGGCGGNRNNFESEDYCMAVCKTMIPPTPLPTNDVDVYFETSADDNEHARFQKAKEQLEIRHRSRMDRVKKEWEEAELQAKNLPKAERQTLIQHFQAMVKALEKEAASEKQQLVETHLARVEAMLNDRRRIALENYLAALQSDPPRPHRILQALRRYVRAENKDRLHTIRHYQHVLAVDPEKAAQMKSQVMTHLHVIEERRNQSLSLLYKVPYVAQEIQEEIDELLQEQRADMDQFTSSISENPVDVRVSSEESEEIPPFHPFHPFPSLSENEDTQPELYHPMKKGSGMAEQDGGLIGAEEKVINSKNKMDENMVIDETLDVKEMIFNAERVGGLEEEPDSVGPLREDFSLSSSALIGLLVIAVAIATVIVISLVMLRKRQYGTISHGIVEVHPMLTPEERHLNKMQNHGYENPTYKYLEQMQI", "length": 765 }, "evidence": [ { "id": "F1P0A7", "url": "https://omabrowser.org/oma/group/F1P0A7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q06481-1", "protein_name": "Amyloid beta precursor like protein 2", "gene_name": "APLP2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAATGTAAAAATGRLLLLLLVGLTAPALALAGYIEALAANAGTGFAVAEPQIAMFCGKLNMHVNIQTGKWEPDPTGTKSCFETKEEVLQYCQEMYPELQITNVMEANQRVSIDNWCRRDKKQCKSRFVTPFKCLVGEFVSDVLLVPEKCQFFHKERMEVCENHQHWHTVVKEACLTQGMTLYSYGMLLPCGVDQFHGTEYVCCPQTKIIGSVSKEEEEEDEEEEEEEDEEEDYDVYKSEFPTEADLEDFTEAAVDEDDEDEEEGEEVVEDRDYYYDTFKGDDYNEENPTEPGSDGTMSDKEITHDVKAVCSQEAMTGPCRAVMPRWYFDLSKGKCVRFIYGGCGGNRNNFESEDYCMAVCKAMIPPTPLPTNDVDVYFETSADDNEHARFQKAKEQLEIRHRNRMDRVKKEWEEAELQAKNLPKAERQTLIQHFQAMVKALEKEAASEKQQLVETHLARVEAMLNDRRRMALENYLAALQSDPPRPHRILQALRRYVRAENKDRLHTIRHYQHVLAVDPEKAAQMKSQVMTHLHVIEERRNQSLSLLYKVPYVAQEIQEEIDELLQEQRADMDQFTASISETPVDVRVSSEESEEIPPFHPFHPFPALPENEDTQPELYHPMKKGSGVGEQDGGLIGAEEKVINSKNKVDENMVIDETLDVKEMIFNAERVGGLEEERESVGPLREDFSLSSSALIGLLVIAVAIATVIVISLVMLRKRQYGTISHGIVEVDPMLTPEERHLNKMQNHGYENPTYKYLEQMQI", "length": 763 }, "evidence": [ { "id": "F1P0A7", "url": "https://omabrowser.org/oma/group/F1P0A7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "secretory vesicle", "id": "GO:0099503", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099503", "evidence": [ { "database": "UniProtKB", "id": "F1P0A7", "url": "https://www.uniprot.org/uniprotkb/F1P0A7" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1P0A7", "url": "https://www.uniprot.org/uniprotkb/F1P0A7" } ], "pmid": "" }, { "name": "cell surface", "id": "GO:0009986", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009986", "evidence": [ { "database": "UniProtKB", "id": "F1P0A7", "url": "https://www.uniprot.org/uniprotkb/F1P0A7" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "F1P0A7", "url": "https://www.uniprot.org/uniprotkb/F1P0A7" } ], "pmid": "" }, { "name": "endomembrane system", "id": "GO:0012505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0012505", "evidence": [ { "database": "UniProtKB", "id": "F1P0A7", "url": "https://www.uniprot.org/uniprotkb/F1P0A7" } ], "pmid": "" }, { "name": "neuron projection", "id": "GO:0043005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043005", "evidence": [ { "database": "UniProtKB", "id": "F1P0A7", "url": "https://www.uniprot.org/uniprotkb/F1P0A7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "serine-type endopeptidase inhibitor activity", "id": "GO:0004867", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004867", "evidence": [ { "database": "UniProtKB", "id": "F1P0A7", "url": "https://www.uniprot.org/uniprotkb/F1P0A7" } ], "pmid": "" }, { "name": "heparin binding", "id": "GO:0008201", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008201", "evidence": [ { "database": "UniProtKB", "id": "F1P0A7", "url": "https://www.uniprot.org/uniprotkb/F1P0A7" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "F1P0A7", "url": "https://www.uniprot.org/uniprotkb/F1P0A7" } ], "pmid": "" }, { "name": "transition metal ion binding", "id": "GO:0046914", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046914", "evidence": [ { "database": "UniProtKB", "id": "F1P0A7", "url": "https://www.uniprot.org/uniprotkb/F1P0A7" } ], "pmid": "" }, { "name": "molecular function activator activity", "id": "GO:0140677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140677", "evidence": [ { "database": "UniProtKB", "id": "F1P0A7", "url": "https://www.uniprot.org/uniprotkb/F1P0A7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "axonogenesis", "id": "GO:0007409", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007409", "evidence": [ { "database": "UniProtKB", "id": "F1P0A7", "url": "https://www.uniprot.org/uniprotkb/F1P0A7" } ], "pmid": "" }, { "name": "central nervous system development", "id": "GO:0007417", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007417", "evidence": [ { "database": "UniProtKB", "id": "F1P0A7", "url": "https://www.uniprot.org/uniprotkb/F1P0A7" } ], "pmid": "" }, { "name": "regulation of protein metabolic process", "id": "GO:0051246", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051246", "evidence": [ { "database": "UniProtKB", "id": "F1P0A7", "url": "https://www.uniprot.org/uniprotkb/F1P0A7" } ], "pmid": "" }, { "name": "positive regulation of macromolecule metabolic process", "id": "GO:0010604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010604", "evidence": [ { "database": "UniProtKB", "id": "F1P0A7", "url": "https://www.uniprot.org/uniprotkb/F1P0A7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 526, "end_pos": 528, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1P0A7-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 753, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1P0A7-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1P0A7" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 526, "end_pos": 528 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { 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"total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1P0T0-1", "uniprot_ac": "F1P0T0", "uniprot_id": "F1P0T0_CHICK", "mass": { "chemical_mass": 226220.0, "monoisotopic_mass": 226220.0 }, "refseq": { "ac": "XP_015156902", "name": "E3 ubiquitin-protein ligase TTC3 isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015156902" }, "gene_names": [ { "name": "TTC3", "type": "recommended", "evidence": [ { "id": "F1P0T0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P0T0" } ] }, { "name": "TTC3", "type": "synonym", "evidence": [ { "id": "XP_015156902", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015156902" } ] } ], "protein_names": [ { "name": "RING-type E3 ubiquitin transferase", "type": "recommended", "evidence": [ { "id": "F1P0T0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P0T0/entry#names_and_taxonomy" } ] }, { "name": "2.3.2.27", "type": "synonym", "evidence": [ { "id": "F1P0T0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P0T0/entry#names_and_taxonomy" } ] }, { "name": "E3 ubiquitin-protein ligase TTC3 isoform X3", "type": "synonym", "evidence": [ { "id": "XP_015156902", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015156902" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015156902", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015156902" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1P0T0", "url": "https://www.uniprot.org/uniprotkb/F1P0T0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TTC3", "url": "https://www.uniprot.org/uniprotkb/F1P0T0", "locus": { "chromosome": "1", "start_pos": 107154234, "end_pos": 107094179, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013135", "url": "https://www.ensembl.org/id/ENSGALG00010013135" } ] } } ], "crossref": [ { "id": "ENSGALG00000016050", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000016050", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd16481", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16481", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "418518", "url": "https://www.ncbi.nlm.nih.gov/gene/418518", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001841", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001841", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011029", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011029", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011990", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011990", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019734", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019734", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043866", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043866", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056870", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056870", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056871", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056871", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056872", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056872", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "CEDVRAK", "url": "https://omabrowser.org/oma/group/CEDVRAK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YQG6", "url": "https://www.orthodb.org/?gene=A0A8V0YQG6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1P0T0", "url": "https://www.orthodb.org/?gene=F1P0T0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR17550", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR17550", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR17550:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR17550:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13639", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13639", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF19179", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19179", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24525", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24525", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24812", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24812", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24905", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24905", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015156902", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015156902", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YQG6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQG6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQG6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQG6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1P0T0", "url": "https://www.uniprot.org/uniprotkb/F1P0T0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1P0T0-1", "url": "https://www.uniprot.org/uniprotkb/F1P0T0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGEPLSESEFAALAFSAGYKSCCELGHGVFVQRSPHKPKTDVDPCEVWCRQPVDKLREYCNVIKIRIFWPLLFQSESNYLVADWGSLQILDWNWKKLCDLELVEDLVDLTKKVVNVPHFIGGILRIGSRLENGFFDVRDALDWIRCTGDINILQKLEKLGDFGWLYLETFFGECKHYITKVALEDCNLVEEFKAVTCENCRKKSESMKQKGNEEFSQGKYDHAIISYTKAIEFCPANHLLYGNRALCLILTKQYKRALADGKRATILKPNWPKGHYHFCKALSLLGEHELALEANERAQELCKNILDGFKDLIQQNDKLKKTLEEIKGTKEYKQKPKNLLLEKKDCGSSKSHLIVSQEQKEIEKDRKQMQFDHKDDHYHQKHDTTIRYPTDGIPRLSVTNMPRTENKVWSLDFQPSQSHQHKGRSKNKPGEPEKKQDHLDLKIDSKSIQDKLVCTVHQVDSTMLLEVVKSLVHDGYTALMDQRCHSAEQMFSQLLNILNPSELKQLNLRVINYVVIIYGHATSLLGIGQPEALTKAEDQFKRIIIQYQQERFDCLAYYGIGKVYLRQNRFLDALNQFKKSQTMINHKIVPGVLTWPTTSQVIEETRTENLQLFLKNCIEECKFPPEPDAICRYQQCHGHSKIQIFFTDPDFKGFIRITCCQQCRVEFHTSCWKKLKTANYSDKNDKDFLQELCFTPDCRGLISKIVIFSSSGLVKREFEQKITKPKEPPRAIIKQKCSSFRKLKRKEEKKIRRKRAREDALNSSKQKIEENQMRNELSQYRNRSDYAGYTGDQVLQRIIQNAEQIKTAVRDASKLLKELLSWFVISEEDYTSYCKTSSMSHAVVEQLIGYLIQEENRVKTRSFIRVLSEMEEVDPKLQRWMKHLNDLGLRATVNFIHQYGQFLKQLDFSILSAPWNEKYGSKFDYVSSSSEGKEILDYFLKPPLEKVRCFIWLLEDNREHFPSLHQALDEFFDKTDNPTIILKKHGNEDILTNGIKVKNKSRKKNYKDSRSVIVLSSGVSTAPQEENTFIEETTLDCTYYEPCIIPEYLRKQLEEFESVYDISNSNSYQRLDDNLNQTCESLYDYFSQILEEHGPMELNNKLLVGEYEHFPEEARKIVEDEGGLKSFLLKSHRFVMVDNFISLRHDVLIKENKNRDETENNEEGNYIFCDAQENSFQNKIQLNPAAKEFKPLSYPEQPHLSTSTDISLESCETPQCLPYSLPTSWQSMLSQDIDPVENTPYFSNVLLYQDFQNQSSFLPQTSWGYQCERTSPVPSPVPLLSNVAKQPGYIYADCVAHQNNDELAISDRNYVSNSFIPAEIETYRDPQILVENSDNAFYEDNFAVANSTSEAECDTQVIKKEKESRGIPVMKNNPHTRMVAVQVNSEVTDRETNTLPFHPFEKQQGDILRMEKEHQVLKEQLKEAQEKYEQLQNRSSEEISVLEELIKKIVEEKGIFKKEVEWLHQSLEIKVKKWQQEKKENQENLKAMRNTAKKHMDTNDRYSKTIDEKEKQYNTCLNTYLETSNKFANEKVKLEELIKKSQDDLKEHEKRAVTAEISVLKNWKESELCKLSGIVARAETNLKMLKSLSSNSASALPDLKSQINYWEVFISNIKKQMEKVKVGYEEKIEKVKNGVRNCLTKIEAADLSSLPSVLRKQSRPAVSDPALVLCSSASAQPNLLPAVSSSEDQGPTTASFNSQAGVKPANANSKVCSASDGSVKTNSKARTGSYADKVSLNSMPKVSGSNTQNIQPNQTHQDDSATQMKPTSNNTFENIIAHLQTIFPGYSSSEFTRFIKDVQRRSGNTLSLSSTEILSRVTDLILDQQNEASASVGRPMMSASSASAGQTGTQSQEAAAEGNISSAPKARPAHKSTSSKNTLPSQPNLQPWGNAGATPKSKWKKLDYIPSSDDPCTICHDELSRDSCELECGHHFHRECIRKWLKEHSSTCPICRIHVLLPEDFPELPARNKYA", "length": 1971, "header": "tr|F1P0T0-1|F1P0T0_CHICK Isoform 1 of RING-type E3 ubiquitin transferase OS=Gallus gallus OX=9031 GN=TTC3 PE=4 SV=2 CANONICAL=F1P0T0-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YQG6-1", "url": "https://www.uniprot.org/uniprotkb/F1P0T0/entry#A0A8V0YQG6-1", "sequence": { "sequence": "MELEPWVNLCLNLSLRPWLSVLVINPAVNCLQILDWNWKKLCDLELVEDLVDLTKKVVNVPHFIGGILRIGSRLENGFFDVRDALDWIRCTGDINILQKLEKLGDFGWLYLETFFGECKHYITKVALEDCNLVEEFKAVTCENCRKKSESMKQKGNEEFSQGKYDHAIISYTKAIEFCPANHLLYGNRALCLILTKQYKRALADGKRATILKPNWPKGHYHFCKALSLLGEHELALEANERAQELCKNILDGFKDLIQQNDKLKKTLEEIKGTKEYKQKPKNLLLEKKDCGSSKSHLIVSQEQKEIEKDRKQMQFDHKDDHYHQKHDTTIRYPTDGIPRLSVTNMPRTENKVWSLDFQPSQSHQHKGRSKNKPGEPEKKQDHLDLKIDSKSIQDKLVCTVHQVDSTMLLEVVKSLVHDGYTALMDQRCHSAEQMFSQLLNILNPSELKQLNLRVINYVVIIYGHATSLLGIGQPEALTKAEDQFKRIIIQYQQERFDCLAYYGIGKVYLRQNRFLDALNQFKKSQTMINHKIVPGVLTWPTTSQVIEETRTENLQLFLKNCIEECKFPPEPDAICRYQQCHGHSKIQIFFTDPDFKGFIRITCCQQCRVEFHTSCWKKLKTANYSDKNDKDFLQELCFTPDCRGLISKIVIFSSSGLVKREFEQKITKPKEPPRAIIKQKCSSFRKLKRKEEKKIRRKRAREDALNSSKQKIEENQMRNELSQYRNRSDYAGYTGDQVLQRIIQNAEQIKTAVRDASKLLKELLSWFVISEEDYTSYCKTSSMSHAVVEQLIGYLIQEENRVKTRSFIRVLSEMEEVDPKLQRWMKHLNDLGLRATVNFIHQYGQFLKQLDFSILSAPWNEKYGSKFDYVSSSSEGKEILDYFLKPPLEKVRCFIWLLEDNREHFPSLHQALDEFFDKTDNPTIILKKHGNEDILTNGIKVKNKSRKKNYKDSRSVIVLSSGVSTAPQEENTFIEETTLDCTYYEPCIIPEYLRKQLEEFESVYDISNSNSYQRLDDNLNQTCESLYDYFSQILEEHGPMELNNKLLVGEYEHFPEEARKIVEDEGGLKSFLLKSHRFVMVDNFISLRHDVLIKENKNRDETENNEEGNYIFCDAQENSFQNKIQLNPAAKEFKPLSYPEQPHLSTSTDISLESCETPQCLPYSLPTSWQSMLSQDIDPVENTPYFSNVLLYQDFQNQSSFLPQTSWGYQCERTSPVPSPVPLLSNVAKQPGYIYADCVAHQNNDELAISDRNYVSNSFIPAEIETYRDPQILVENSDNAFYEDNFAVANSTSEAECDTQVIKKEKESRGIPVMKNNPHTRMVAVQVNSEVTDRETNTLPFHPFEKQQGDILRMEKEHQVLKEQLKEAQEKYEQLQNRSSEEISVLEELIKKIVEEKGIFKKEVEWLHQSLEIKVKKWQQEKKENQENLKAMRNTAKKHMDTNDRYSKTIDEKEKQYNTCLNTYLETSNKFANEKVKLEELIKKSQDDLKEHEKRAVTAEISVLKNWKESELCKLSGIVARAETNLKMLKSLSSNSASALPDLKSQINYWEVFISNIKKQMEKVKVGYEEKIEKVKNGVRNCLTKIEAADLSSLPSVLRKQSRPAVSDPALVLCSSASAQPNLLPAVSSSEDQGPTTASFNSQAGVKPANANSKVCSASDGSVKTNSKARTGSYADKVSLNSMPKVSGSNTQNIQPNQTHQDDSATQMKPTSNNTFENIIAHLQTIFPGYSSSEFTRFIKDVQRRSGNTLSLSSTEILSRVTDLILDQQNEASASVGRPMMSASSASAGQTGTQSQEAAAEGNISSAPKARPAHKSTSSKNTLPSQPNLQPWGNAGATPKSKWKKLDYIPSSDDPCTICHDELSRDSCELECGHHFHRECIRKWLKEHSSTCPICRIHVLLPEDFPELPARNKYA", "length": 1915, "header": "tr|A0A8V0YQG6-1|A0A8V0YQG6_CHICK Computationally mapped isoform of RING-type E3 ubiquitin transferase OS=Gallus gallus OX=9031 GN=TTC3 PE=4 SV=1 CANONICAL=F1P0T0-1" }, "locus": { "chromosome": "1", "start_pos": 107153084, "end_pos": 107094378, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031521.1", "url": "https://www.ensembl.org/id/ENSGALT00010031521.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018411.1", "url": "https://www.ensembl.org/id/ENSGALP00010018411.1" } ] } }, { "isoform_ac": "F1P0T0-1", "url": "https://www.uniprot.org/uniprotkb/F1P0T0/entry#F1P0T0-1", "sequence": { "sequence": "MGEPLSESEFAALAFSAGYKSCCELGHGVFVQRSPHKPKTDVDPCEVWCRQPVDKLREYCNVIKIRIFWPLLFQSESNYLVADWGSLQILDWNWKKLCDLELVEDLVDLTKKVVNVPHFIGGILRIGSRLENGFFDVRDALDWIRCTGDINILQKLEKLGDFGWLYLETFFGECKHYITKVALEDCNLVEEFKAVTCENCRKKSESMKQKGNEEFSQGKYDHAIISYTKAIEFCPANHLLYGNRALCLILTKQYKRALADGKRATILKPNWPKGHYHFCKALSLLGEHELALEANERAQELCKNILDGFKDLIQQNDKLKKTLEEIKGTKEYKQKPKNLLLEKKDCGSSKSHLIVSQEQKEIEKDRKQMQFDHKDDHYHQKHDTTIRYPTDGIPRLSVTNMPRTENKVWSLDFQPSQSHQHKGRSKNKPGEPEKKQDHLDLKIDSKSIQDKLVCTVHQVDSTMLLEVVKSLVHDGYTALMDQRCHSAEQMFSQLLNILNPSELKQLNLRVINYVVIIYGHATSLLGIGQPEALTKAEDQFKRIIIQYQQERFDCLAYYGIGKVYLRQNRFLDALNQFKKSQTMINHKIVPGVLTWPTTSQVIEETRTENLQLFLKNCIEECKFPPEPDAICRYQQCHGHSKIQIFFTDPDFKGFIRITCCQQCRVEFHTSCWKKLKTANYSDKNDKDFLQELCFTPDCRGLISKIVIFSSSGLVKREFEQKITKPKEPPRAIIKQKCSSFRKLKRKEEKKIRRKRAREDALNSSKQKIEENQMRNELSQYRNRSDYAGYTGDQVLQRIIQNAEQIKTAVRDASKLLKELLSWFVISEEDYTSYCKTSSMSHAVVEQLIGYLIQEENRVKTRSFIRVLSEMEEVDPKLQRWMKHLNDLGLRATVNFIHQYGQFLKQLDFSILSAPWNEKYGSKFDYVSSSSEGKEILDYFLKPPLEKVRCFIWLLEDNREHFPSLHQALDEFFDKTDNPTIILKKHGNEDILTNGIKVKNKSRKKNYKDSRSVIVLSSGVSTAPQEENTFIEETTLDCTYYEPCIIPEYLRKQLEEFESVYDISNSNSYQRLDDNLNQTCESLYDYFSQILEEHGPMELNNKLLVGEYEHFPEEARKIVEDEGGLKSFLLKSHRFVMVDNFISLRHDVLIKENKNRDETENNEEGNYIFCDAQENSFQNKIQLNPAAKEFKPLSYPEQPHLSTSTDISLESCETPQCLPYSLPTSWQSMLSQDIDPVENTPYFSNVLLYQDFQNQSSFLPQTSWGYQCERTSPVPSPVPLLSNVAKQPGYIYADCVAHQNNDELAISDRNYVSNSFIPAEIETYRDPQILVENSDNAFYEDNFAVANSTSEAECDTQVIKKEKESRGIPVMKNNPHTRMVAVQVNSEVTDRETNTLPFHPFEKQQGDILRMEKEHQVLKEQLKEAQEKYEQLQNRSSEEISVLEELIKKIVEEKGIFKKEVEWLHQSLEIKVKKWQQEKKENQENLKAMRNTAKKHMDTNDRYSKTIDEKEKQYNTCLNTYLETSNKFANEKVKLEELIKKSQDDLKEHEKRAVTAEISVLKNWKESELCKLSGIVARAETNLKMLKSLSSNSASALPDLKSQINYWEVFISNIKKQMEKVKVGYEEKIEKVKNGVRNCLTKIEAADLSSLPSVLRKQSRPAVSDPALVLCSSASAQPNLLPAVSSSEDQGPTTASFNSQAGVKPANANSKVCSASDGSVKTNSKARTGSYADKVSLNSMPKVSGSNTQNIQPNQTHQDDSATQMKPTSNNTFENIIAHLQTIFPGYSSSEFTRFIKDVQRRSGNTLSLSSTEILSRVTDLILDQQNEASASVGRPMMSASSASAGQTGTQSQEAAAEGNISSAPKARPAHKSTSSKNTLPSQPNLQPWGNAGATPKSKWKKLDYIPSSDDPCTICHDELSRDSCELECGHHFHRECIRKWLKEHSSTCPICRIHVLLPEDFPELPARNKYA", "length": 1971, "header": "tr|F1P0T0-1|F1P0T0_CHICK Isoform 1 of RING-type E3 ubiquitin transferase OS=Gallus gallus OX=9031 GN=TTC3 PE=4 SV=2 CANONICAL=F1P0T0-1" }, "locus": { "chromosome": "1", "start_pos": 107153084, "end_pos": 107094833, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031560.1", "url": "https://www.ensembl.org/id/ENSGALT00010031560.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018436.1", "url": "https://www.ensembl.org/id/ENSGALP00010018436.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A8M3BCR2-1", "protein_name": "RING-type E3 ubiquitin transferase", "gene_name": "ttc3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSDSDDSDLEEGPNVQRHKTKIVYHAQFPYIHMEPPDIVYERWCKMKLKRKQDLGHLMHVSVFWWHILLRQQENHPTTAWAVKMGFLDSNVSNDLSLKRLEKMEILESILATMERGLSLRDVENKARAVVSLSQRFFQEEDCLTEAIRWLLDSGDPDLGQKLMDLGSVEVRYLTLSFVFMEYARYIQVVSCSKKKALMEMKFEPDSWSLSKSDEMKNKGNEHFQKKKYDVALKWYSKAIKYHPNNHILYGNRALCLLRSGKYLKALGDGKRAIVLQPDWAKGHYRFCDALFYLGEHQRALLANQQAQDACRADVEGQKDLLQQHERFQSELQEARDMKTKKPDPKKVSSKARSHTAGASSAAHLKTSAPPETPPEPQTKKSEKQKQQADTSGPSGARAHTDGGADRLRDVSSESSPRKAKKASSSTAEKPAVRSKLPAAADRASAPAEVVSAAAVRERFCAAVLEAHVALSDQRCHNAQQSFSVALAILESSSTTELGLTELDKSVLLYGYATALLETGQPEELAEAEKLFAKLESTERKFQSLVHYGMGRVYLKENRFAKARECFSNALLMIQRHITPGKLTWPTTKAIVEETQPAWLQEHLESLVEVCRFPPKADAVCRHQQCVSHSVQIYFSDPDFKGFIQLVCCQSCRIEFHMSCWRKLKTLSFADKNDKDFLKDSCFTPDCAGQICHILIFGSTGLIKCEFKSSIPKARAAGRSRLRQQCTSIKKLMSKNDRKLRRKQQRLAARSSHQEKREVMREEAAKEQPADRASPRDCIYMDRVLQQIHDNKALFKEEPVSISCFWEHLRPWLDLFESKGQESVLNSRRGVGVLSELVDLLLESRNRVWARVFIQTLGSTLHIKPRLQHWAQQLDDTGLKAAQSFINRYRSHLEDLELKPLLSFPPLQESLVEKLGSVTELFDRDDFTVMEYLRQAPAKEMRLFIWTLESSRERYQSCHTILDQYFEDDAVCLVIKKTDDDEHMSSVFKSKNRHRKKKHKELKSVIVLSGMRAGHSRDEDDEDELFSEEDSLMFLNDMDPFSVPDHLRYQLAEFEENYSGSAQRSYYERMLDNHPDPTKETLYDYFAQVLEEHGPLCATDPLLVGELQNFPLEAQQQIADAGGLQAFLLQSLRFTMTERLIGLMKHAVCLSESSNTHSQILNPSASEFWPLSGEPPSSTGEPALLLPDPYTDEEDQLSAAEMTESDTEETRAEKHTAVRAQDFQDRTDVSVNTEPCAPFENNSGELMGLQKRRLYLLEELQRIRADGEAEQQRRQEELTELQEDTHNISQRMQIASTELSMFQQKLEEEVKKDQQEKKENQETLRSLKMEIKELVELQESLSRDISVRNRQYEAELELFLDVSNQCAAERLSLEDEIKRFRDACVKAERRSASAQLCVLQSRREHALRRLRMTVSEGKMVVKHLSDVALSSPSAALLSAIEDWKRHVSEAEGRIHATEEECEAQMQAVQQGSRLCSLPDISTPSVPSAPALPALQTPVSSAAPEESSSRRSAAPQHLSVYERIVERLHIMFPHYDRLVLNKFLQEVRSSCSGGVLSSLTYNEVINRVAQLILDHQENICQQMNITAGDAADLSCPPSDCTLRAAGTPPLTHVWKNVPEKHRNSALVLNMEDPCIICHEDMSAEDLCVLECRHSFHRECIKSWLKEQSTCPTCREHALLPEDFPLLPGRQRRTHTAS", "length": 1695 }, "evidence": [ { "id": "F1P0T0", "url": "https://omabrowser.org/oma/group/F1P0T0/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "D3ZSP7-1", "protein_name": "E3 ubiquitin-protein ligase TTC3", "gene_name": "Ttc3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPGHRGAPHLPPWVCGLCSMDDFAEGGLSLADDILLEDYPYEDDCICTPDFTTDDYVRVTQLYYEGVGMQYKDYAQSEKNLEYDICNIWCSKPLSILQDYCDAIKLYIFWPLLFQHQHSSIISRLHPCVEAIRSRAAEISLKKLQHLELMEDIVDLAKKVANDSFLIEGLLKIGYKIENKILAMEDALNWIKYTGDVTILPKLGSVDSGWPMLSIFFTEYKYHITRVVTENCNLLEEFRRHSCMQCVKQGELMKMRGNEEFAKEKFEIAVIYYTRAIEYRPENHLLYGNRALCFLRMGQFRNALSDGKRAIVLKNTWPKGHYRYCDALSMLGEYDWALQANIKAQKLCKNDPEGIKDLIQQHIKLQKQIEDLQGRTSNRNPIKAFYESRAYIPRNSSAPAFRTSLNFVETERGFRKTKYRMANGGGHQNQKVADEALKGDDCDCHPEFLPPPSQPPRHKGKQKSRNNESEKPSSNSQVTLQVDLKSILEKQFSKSSRAAHQDFANIMKMLRSLIQDGYTALLEQRCRSAAQAFTELLNGLDPQKIKQLNLAMINYVLVVYGLAVSLLGIGRPEELSEAENQFKRIIEHYPNEGLDCLAYCGIGKVYLKKNRFLEALNHFEKAKTLICRLPGILTWPTSNVIIEESKPEKVKVMLEKFVEECKFPPVPDAVCCYQKCRGFSKIQIYLTDPDFKGFIRISCCQYCKVEFHMNCWKKLKTTTFNDKIDKDFLQGICLTPDCEGIISKIIIFSSGGQVKCEFEHKVVKEKAPSRPVLKQKCSSLEKLRLKEDKKLKRKIQKQEAKKLAQERMEEDLRESNPPKPEEPEETVESAQSCQFLDDRILQCIKQNADKIKSVVLNTSTLLKELLSWKVLSTEDYTTCFSSKNFVHEAVDYVIGHLIQEKNRVKTRIFLHVLSELKELDPKLAPWIQRLNSFGLDATGPFFTRYGASLKELDFNIVTFLWSEKYGHKLGSIEGKQLDYFCEPASVMEARCLIWLLEEHRDKFPALHSALDEFFDIMDSRCTVLRKQDSDEMPFGCIKVKNKGKKKKPKDSKPMLVGSGTASVTPSSETVTPEDHNRRNSDSAGPFAVPDHLRQDVEEFEALYDQHSSEYVVRNKKLWDINPKQKCSTLYDYFSQLLEEHGPLDMSDRMFSEEYEFFPEETRQILEKAGGLKSFLLGCPRFVVIDNCIALKKVASRLKKKRKKKNIKTKVEEISKTGEYLRVKLPLNPTAREFQPDVKSEAAAEDVTSIPGPADSSAPAAEDLKPQLDSDSSSGSASEDSRLEVVSPDLPTPLCEDASPSPTPAPEDAKPTYWTQSHLVTGFCTYLPFQGFGIAQSRPAYINMVPSLSQFTSIYTPLANISSEYPMPRSMPVVPSFVASERADGNAAAYFESHRLNTENASDDHTASETQILEGPLGMCVKSQSSTADARTALSEPEGNSRHSGSSDSLWEASLENVSGITDVPPAPSVAIQVSRSLIHQEVNTEPYAPFERQQGDLSQKEKECHLLREQLQVACEECEQMELRSSQETRDLEEKLQRHAEENKVSLPELQWALGKLDREIKKWHQEKKEIQERLKALKKKIKKVINTSDMSAQKNDGLDKECESQPDQSLGISSALTDEKAKVEESVRKGKELYEESQQRAVAAEVSVLENWKEREVCKLQGVATQAEACLKSLKLMNSDSAAYPDVECDILSWETFLSTVTEEIENTKCQFEEQIKAIKSGSRLSDLSSVQVSELLFPACSMIHPQLLSESSRHEDHGLVACVDSMTGAVLNDPYVGPDSGCSEEVPELSLGSPTHHPEGAQQLEVKKASQVSPSEQNPEADEKPSGQATRSSQSQKNPFNSIIEHLSVIFPCYASSELSGFIKKVRNKSKNSFSGLSIEEIVERVTEHIVEEQKKKKPNPGKDKKTSEAHPAASVSKSSPSPPLAAAGPSAKTKGQKKDDVPAPDGNSCQICHEIFKSKNMRVLKCGHKFHKGCFKQWLKGQSTCPTCGSSDLLSEE", "length": 2000 }, "evidence": [ { "id": "F1P0T0", "url": "https://omabrowser.org/oma/group/F1P0T0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O88196-1", "protein_name": "E3 ubiquitin-protein ligase TTC3", "gene_name": "Ttc3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDDFAEGGLSLADDILLEDYPYEDDCICTPDFTTDDYVRVTQLYYEGVGMQYKDYAQSEKNLEYDICNIWCSKPLSILQDYCDAIKLYIFWPLLFQHQHSSIISRLHPCVEAIRSRAAEISLKKLQHLELMEDIVDLAKKVANDSFLIEGLLKIGYKIENKILAMEDALNWIKYTGDVTILPKLGSVDNCWPMLSIFFTEYKYHITRVVTENCNLLEEFRRHSCMQCVKQGELMKMRGNEEFSKEKFEIAVIYYTRAIEYRPENHLLYGNRALCFLRMGQFRNALSDGKRAIVLKNTWPKGHYRYCDALCMLGEYDWALQANIKAQKLCKNDPEGIKDLIQQHVKLQKQIEDLQGRTSNKNPIKAFYESRAYIPRNSSAPAFRTSLNFVETERGFRKTKYKMANGGDQNQKVADEALKGDDCDCHPEFLPPPSQPPRHKGKQKSRNNESEKPSFNSEVSLQVDLKSILEKQFSKSSRAAHQDFANIMKMLRSLIQDGYTALLEQRCRSAAQAFTELLNGLDPQKIKQLNLAMINYVLVVYGLAVSLLGIGRPEELSEAENQFKRIIEHYPNEGLDCLAYCGIGKVYLKKNRFLEALNHFEKAKTLISRLPGILTWPTSNVIIEESKPEKVKVMLEKFVEECKFPPVPDAVCCYQKCRGYSKIQIYLTDPDFKGFIRISCCQYCKVEFHMNCWKKLKTTTFNDKIDKDFLQGICLTPDCEGIISKIIIYSSGGQVKCEFEHKVIKEKVPSRPVLKQKCSSLEKLRLKEDKKLKRKIQKQEAKKLAQERMEEDLRESNPPKNEEPEETSDSAQRCQFLDDRILQCIKQNADKIKSVVLNTSTLLKELLSWKVLSTEDYTTCFSSKNFVHEAVDYVIGHLIQEKNRVKTRIFLHVLSELKELDPKLAPWIQRLNSFGLDAIGPFFTRYGASLKELDFHVVTVLWDEKYGHKLGSIEGKQLDYFFEPASAMEARCLIWLLEEHRDKFPALHSALDEFFDIMDSRCTVLRKQDSDEMPFGCIKVKNKGKKKKPKDSKPMLVGSGAASVAPSSEAVTPEDHSRRNSDSAGPFAVPDHLRQDVEEFEALYDQHSSEYVVRNKKLWDINPKQKCSTLYDYFSQLLEEHGPLDMSDRMFSEEYEFFPEETRQILEKAGGLKSFLLGCPRFVVIDNCIALKKVASRLKKKRKKKNMKAKVEDISKTGEYLRVKLPLNPTAREFQPDVKSEALSEDVKSIPGPADSSTLAAEDLKAQLDSDSSSGSASEDSRLEVASPDSPTPLCEDASPSPTPAPEEAKPTYWAQSHLVTGFCTYLPFQGFGITQRPAYINMVPSLSQFTSIYTPLANISSEYPMQRSMPVVPSFVASNRADENAAAYFESPNLNTEHDSGDHMASETQILEDTLGVCVRSQGSAADADPALSEPEGNSEHSGSSDSLWEASLENVSGTTDAPAAPSVAIQVSRSMVHQEVNTEPYEPFETQQGDLSQKEKECHLLREQLKVACENCEQIELRSSQEIKDLEEKLQRHTEENKISKTELDWFLQDLDREIKKWQQEKKEIQERLKALKKKIKKVINTSEMSAQKNDGFDKECEPHPDQSLGFSSALTDEKTKAEESVRKGKELYEESHQRAVAAEVSVLENWKEREVCKLQGVASQSEAYLKSLKLMSSDSATYPDVEYDILSWESFLSTVREEIESKKSQFEEHIKAIKNGSRLSDLSSVQLSEVSFPGCSTIHPQFLSESSGHEDPGLVACVDSMTGAVLNDPYMDSASGCPEEVPELSLGSPTHQPEVTQQLELKGASQVSPSEQSPEADEKLSGQATRSSQSPKKPSNSIIEHLSVIFPCYTSTELAGFIKKVRNKTKNSFSGLTIEEIVEKVTEHIVDEQKKKKPNPGKDKKTSEAHSAASVAKSSQSPPLAAAGPSARTKGQKKDDVPAPDGNSCEICHEIFKSKNMRVLKCGHKFHKGCFKQWLKGQSTCPTCGSSDLLSEE", "length": 1979 }, "evidence": [ { "id": "F1P0T0", "url": "https://omabrowser.org/oma/group/F1P0T0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P53804-1", "protein_name": "E3 ubiquitin-protein ligase TTC3", "gene_name": "TTC3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDNFAEGDFTVADYALLEDCPHVDDCVFAAEFMSNDYVRVTQLYCDGVGVQYKDYIQSERNLEFDICSIWCSKPISVLQDYCDAIKINIFWPLLFQHQNSSVISRLHPCVDANNSRASEINLKKLQHLELMEDIVDLAKKVANDSFLIGGLLRIGCKIENKILAMEEALNWIKYAGDVTILTKLGSIDNCWPMLSIFFTEYKYHITKIVMEDCNLLEELKTQSCMDCIEEGELMKMKGNEEFSKERFDIAIIYYTRAIEYRPENYLLYGNRALCFLRTGQFRNALGDGKRATILKNTWPKGHYRYCDALSMLGEYDWALQANIKAQKLCKNDPEGIKDLIQQHVKLQKQIEDLQGRTANKDPIKAFYENRAYTPRSLSAPIFTTSLNFVEKERDFRKINHEMANGGNQNLKVADEALKVDDCDCHPEFSPPSSQPPKHKGKQKSRNNESEKFSSSSPLTLPADLKNILEKQFSKSSRAAHQDFANIMKMLRSLIQDGYMALLEQRCRSAAQAFTELLNGLDPQKIKQLNLAMINYVLVVYGLAISLLGIGQPEELSEAENQFKRIIEHYPSEGLDCLAYCGIGKVYLKKNRFLEALNHFEKARTLIYRLPGVLTWPTSNVIIEESQPQKIKMLLEKFVEECKFPPVPDAICCYQKCHGYSKIQIYITDPDFKGFIRISCCQYCKIEFHMNCWKKLKTTTFNDKIDKDFLQGICLTPDCEGVISKIIIFSSGGEVKCEFEHKVIKEKVPPRPILKQKCSSLEKLRLKEDKKLKRKIQKKEAKKLAQERMEEDLRESNPPKNEEQKETVDNVQRCQFLDDRILQCIKQYADKIKSGIQNTAMLLKELLSWKVLSTEDYTTCFSSRNFLNEAVDYVIRHLIQENNRVKTRIFLHVLSELKEVEPKLAAWIQKLNSFGLDATGTFFSRYGASLKLLDFSIMTFLWNEKYGHKLDSIEGKQLDYFSEPASLKEARCLIWLLEEHRDKFPALHSALDEFFDIMDSRCTVLRKQDSGEAPFSSTKVKNKSKKKKPKDSKPMLVGSGTTSVTSNNEIITSSEDHSNRNSDSAGPFAVPDHLRQDVEEFEALYDQHSNEYVVRNKKLWDMNPKQKCSTLYDYFSQFLEEHGPLDMSNKMFSAEYEFFPEETRQILEKAGGLKPFLLGCPRFVVIDNCIALKKVASRLKKKRKKKNIKTKVEEISKAGEYVRVKLQLNPAAREFKPDVKSKPVSDSSSAPAFENVKPKPVSANSPKPACEDVKAKPVSDNSSRQVSEDGQPKGVSSNSPKPGSEDANYKRVSCNSPKPVLEDVKPTYWAQSHLVTGYCTYLPFQRFDITQTPPAYINVLPGLPQYTSIYTPLASLSPEYQLPRSVPVVPSFVANDRADKNAAAYFEGHHLNAENVAGHQIASETQILEGSLGISVKSHCSTGDAHTVLSESNRNDEHCGNSNNKCEVIPESTSAVTNIPHVQMVAIQVSWNIIHQEVNTEPYNPFEERQGEISRIEKEHQVLQDQLQEVYENYEQIKLKGLEETRDLEEKLKRHLEENKISKTELDWFLQDLEREIKKWQQEKKEIQERLKSLKKKIKKVSNASEMYTQKNDGKEKEHELHLDQSLEISNTLTNEKMKIEEYIKKGKEDYEESHQRAVAAEVSVLENWKESEVYKLQIMESQAEAFLKKLGLISRDPAAYPDMESDIRSWELFLSNVTKEIEKAKSQFEEQIKAIKNGSRLSELSKVQISELSFPACNTVHPELLPESSGDDGQGLVTSASDVTGNHAALHRDPSVFSAGDSPGEAPSALLPGPPPGQPEATQLTGPKRAGQAALSERSPVADRKQPVPPGRAARSSQSPKKPFNSIIEHLSVVFPCYNSTELAGFIKKVRSKNKNSLSGLSIDEIVQRVTEHILDEQKKKKPNPGKDKRTYEPSSATPVTRSSQGSPSVVVAPSPKTKGQKAEDVPVRIALGASSCEICHEVFKSKNVRVLKCGHKYHKGCFKQWLKGQSACPACQGRDLLTEESPSGRGWPSQNQELPSCSSR", "length": 2025 }, "evidence": [ { "id": "F1P0T0", "url": "https://omabrowser.org/oma/group/F1P0T0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1P0T0", "url": "https://www.uniprot.org/uniprotkb/F1P0T0" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1P0T0", "url": "https://www.uniprot.org/uniprotkb/F1P0T0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "F1P0T0", "url": "https://www.uniprot.org/uniprotkb/F1P0T0" } ], "pmid": "" }, { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "F1P0T0", "url": "https://www.uniprot.org/uniprotkb/F1P0T0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "ubiquitin-dependent protein catabolic process", "id": "GO:0006511", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006511", "evidence": [ { "database": "UniProtKB", "id": "F1P0T0", "url": "https://www.uniprot.org/uniprotkb/F1P0T0" } ], "pmid": "" }, { "name": "protein K48-linked ubiquitination", "id": "GO:0070936", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070936", "evidence": [ { "database": "UniProtKB", "id": "F1P0T0", "url": "https://www.uniprot.org/uniprotkb/F1P0T0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1076, "end_pos": 1078, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1253, "end_pos": 1255, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1346, "end_pos": 1348, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1433, "end_pos": 1435, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1753, "end_pos": 1755, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1769, "end_pos": 1771, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1859, "end_pos": 1861, "annotation": "n_glycosylation_sequon" }, { "start_pos": 679, "end_pos": 681, "annotation": "n_glycosylation_sequon" }, { "start_pos": 762, "end_pos": 764, "annotation": "n_glycosylation_sequon" }, { "start_pos": 782, "end_pos": 784, "annotation": "n_glycosylation_sequon" }, { "start_pos": 999, "end_pos": 1001, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.3.2.27", "ec_name": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "2.3.2.27", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.3.2.27" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1076, "end_pos": 1078 }, { "start_pos": 1253, "end_pos": 1255 }, { "start_pos": 1346, "end_pos": 1348 }, { "start_pos": 1433, "end_pos": 1435 }, { "start_pos": 1753, "end_pos": 1755 }, { "start_pos": 1769, "end_pos": 1771 }, { "start_pos": 1859, "end_pos": 1861 }, { "start_pos": 679, "end_pos": 681 }, { "start_pos": 762, "end_pos": 764 }, { "start_pos": 782, "end_pos": 784 }, { "start_pos": 999, "end_pos": 1001 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1P0Z9-1", "uniprot_ac": "F1P0Z9", "uniprot_id": "F1P0Z9_CHICK", "mass": { "chemical_mass": 70571.0, "monoisotopic_mass": 70571.0 }, "refseq": { "ac": "XP_417735", "name": "mannosyl-oligosaccharide 1,2-alpha-mannosidase IC isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_417735" }, "gene_names": [ { "name": "MAN1C1", "type": "recommended", "evidence": [ { "id": "F1P0Z9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P0Z9" } ] }, { "name": "MAN1C1", "type": "synonym", "evidence": [ { "id": "XP_417735", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_417735" } ] } ], "protein_names": [ { "name": "alpha-1,2-Mannosidase", "type": "recommended", "evidence": [ { "id": "F1P0Z9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P0Z9/entry#names_and_taxonomy" } ] }, { "name": "3.2.1.-", "type": "synonym", "evidence": [ { "id": "F1P0Z9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P0Z9/entry#names_and_taxonomy" } ] }, { "name": "mannosyl-oligosaccharide 1,2-alpha-mannosidase IC isoform X1", "type": "synonym", "evidence": [ { "id": "XP_417735", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_417735" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052554.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jan 4, 2016 this sequence version replaced XP_417735.3. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_417735", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_417735" } ] }, { "annotation": "Involved in the maturation of Asn-linked oligosaccharides. Progressively trim alpha-1,2-linked mannose residues from Man(9)GlcNAc(2) to produce Man(5)GlcNAc(2).", "evidence": [ { "database": "UniProtKB", "id": "F1P0Z9", "url": "https://www.uniprot.org/uniprotkb/F1P0Z9#function" }, { "database": "UniProtKB", "id": "ARBA00054774", "url": "https://www.uniprot.org/uniprotkb/ARBA00054774#function" }, { "database": "UniProtKB", "id": "A0A8V0YZB4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZB4#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1P0Z9", "url": "https://www.uniprot.org/uniprotkb/F1P0Z9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MAN1C1", "url": "https://www.uniprot.org/uniprotkb/F1P0Z9", "locus": { "chromosome": "23", "start_pos": 2663938, "end_pos": 2706565, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010015573", "url": "https://www.ensembl.org/id/ENSGALG00010015573" } ] } } ], "crossref": [ { "id": "F1P0Z9", "url": "https://alphafold.ebi.ac.uk/entry/F1P0Z9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000001038", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000001038", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "419588", "url": "https://www.ncbi.nlm.nih.gov/gene/419588", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001382", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001382", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012341", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012341", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036026", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036026", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050749", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050749", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:419588", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419588", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "NICFACL", "url": "https://omabrowser.org/oma/group/NICFACL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YZB4", "url": "https://www.orthodb.org/?gene=A0A8V0YZB4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1P0Z9", "url": "https://www.orthodb.org/?gene=F1P0Z9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11742", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11742", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11742:SF28", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11742:SF28", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01532", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01532", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-964827", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-964827", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_417735", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_417735", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "56008", "url": "https://www.rhea-db.org/rhea/56008", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "56028", "url": "https://www.rhea-db.org/rhea/56028", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YZB4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZB4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YZB4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZB4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1P0Z9", "url": "https://www.uniprot.org/uniprotkb/F1P0Z9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1P0Z9-1", "url": "https://www.uniprot.org/uniprotkb/F1P0Z9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVLPRKLPGMPGWPAALGLRLPQKFLFLLFLSGLLTLCFGALFLLPDSSRFKRLFLPRRATSSSSSSSSSSTRDTELPRSPPAAAEPRHASPAAPRRLREKLRARNAAPAAHTAPASRPQGPDGERPAEVGTGAPRESRAPFHFDYERFRQSLRHPVRGGRPDQDPDTRARKMKIKEMMKFAWDNYKQYALGKNELRPLTKNGHIGNMFGGLRGATVVDALDTLYIMELEEEFQEAKTWVEKSFDLNVNGEASLFEVNIRYIGGLLAAYYLTGEEVFKSKALELGEKLLPAFNTPTGIPRGVINLGSGMSWSWGWASAGSSILAEFGTLHLEFLHLSELSGNPVFAEKVLNIRKVLKRVEKPQGLYPNFLSPVTGNWVQHHVSIGGLGDSFYEYLIKSWLMSDKKDSEAKKMYDDALEAIEKHLVKKSAGGLTYIAEWRGGILDHKMGHLACFSGGMIALGAEHGGEERKQHYMDLAAEITNTCHESYARSDTKLGPEAFRFDAGTEAMATRLSERYYILRPEVVESYVYMWRLTHDVKYRQWGWEVVKALEKHCRVEAGFSGIRDVYTTVPTHDNMQQSFFLAETLKYLYLLFCEDDVLSLDDWVFNTEAHPLPVNHSNFKAKASVQ", "length": 628, "header": "tr|F1P0Z9-1|F1P0Z9_CHICK Isoform 1 of alpha-1,2-Mannosidase OS=Gallus gallus OX=9031 GN=MAN1C1 PE=3 SV=5 CANONICAL=F1P0Z9-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YZB4-1", "url": "https://www.uniprot.org/uniprotkb/F1P0Z9/entry#A0A8V0YZB4-1", "sequence": { "sequence": "MKIKEMMKFAWDNYKQYALGKNELRPLTKNGHIGNMFGGLRGATVVDALDTLYIMELEEEFQEAKTWVEKSFDLNVNGEASLFEVNIRYIGGLLAAYYLTGEEVFKSKALELGEKLLPAFNTPTGIPRGVINLGSGMSWSWGWASAGSSILAEFGTLHLEFLHLSELSGNPVFAEKVLNIRKVLKRVEKPQGLYPNFLSPVTGNWVQHHVSIGGLGDSFYEYLIKSWLMSDKKDSEAKKMYDDALEAIEKHLVKKSAGGLTYIAEWRGGILDHKMGHLACFSGGMIALGAEHGGEERKQHYMDLAAEITNTCHESYARSDTKLGPEAFRFDAGTEAMATRLSERYYILRPEVVESYVYMWRLTHDVKYRQWGWEVVKALEKHCRVEAGFSGIRDVYTTVPTHDNMQQSFFLAETLKYLYLLFCEDDVLSLDDWVFNTEAHPLPVNHSNFKAKASVQ", "length": 456, "header": "tr|A0A8V0YZB4-1|A0A8V0YZB4_CHICK Computationally mapped isoform of alpha-1,2-Mannosidase OS=Gallus gallus OX=9031 GN=MAN1C1 PE=3 SV=1 CANONICAL=F1P0Z9-1" }, "locus": { "chromosome": "23", "start_pos": 2705035, "end_pos": 2664674, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010037464.1", "url": "https://www.ensembl.org/id/ENSGALT00010037464.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021698.1", "url": "https://www.ensembl.org/id/ENSGALP00010021698.1" } ] } }, { "isoform_ac": "F1P0Z9-1", "url": "https://www.uniprot.org/uniprotkb/F1P0Z9/entry#F1P0Z9-1", "sequence": { "sequence": "MVLPRKLPGMPGWPAALGLRLPQKFLFLLFLSGLLTLCFGALFLLPDSSRFKRLFLPRRATSSSSSSSSSSTRDTELPRSPPAAAEPRHASPAAPRRLREKLRARNAAPAAHTAPASRPQGPDGERPAEVGTGAPRESRAPFHFDYERFRQSLRHPVRGGRPDQDPDTRARKMKIKEMMKFAWDNYKQYALGKNELRPLTKNGHIGNMFGGLRGATVVDALDTLYIMELEEEFQEAKTWVEKSFDLNVNGEASLFEVNIRYIGGLLAAYYLTGEEVFKSKALELGEKLLPAFNTPTGIPRGVINLGSGMSWSWGWASAGSSILAEFGTLHLEFLHLSELSGNPVFAEKVLNIRKVLKRVEKPQGLYPNFLSPVTGNWVQHHVSIGGLGDSFYEYLIKSWLMSDKKDSEAKKMYDDALEAIEKHLVKKSAGGLTYIAEWRGGILDHKMGHLACFSGGMIALGAEHGGEERKQHYMDLAAEITNTCHESYARSDTKLGPEAFRFDAGTEAMATRLSERYYILRPEVVESYVYMWRLTHDVKYRQWGWEVVKALEKHCRVEAGFSGIRDVYTTVPTHDNMQQSFFLAETLKYLYLLFCEDDVLSLDDWVFNTEAHPLPVNHSNFKAKASVQ", "length": 628, "header": "tr|F1P0Z9-1|F1P0Z9_CHICK Isoform 1 of alpha-1,2-Mannosidase OS=Gallus gallus OX=9031 GN=MAN1C1 PE=3 SV=5 CANONICAL=F1P0Z9-1" }, "locus": { "chromosome": "23", "start_pos": 2705551, "end_pos": 2664674, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010037459.1", "url": "https://www.ensembl.org/id/ENSGALT00010037459.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021694.1", "url": "https://www.ensembl.org/id/ENSGALP00010021694.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "gga:419588", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419588", "resource": "KEGG Pathway" }, { "id": "R-GGA-964827", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-964827", "resource": "Reactome", "description": "Progressive trimming of alpha-1,2-linked mannose residues from Man9/8/7GlcNAc2 to produce Man5GlcNAc2" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I5ZVG8-1", "protein_name": "alpha-1,2-Mannosidase", "gene_name": "Man1c1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLVRKVPGFVPASSWGLRLPQKFLFLLFLSGLVTLCFGALFLLPHSSRLKRLFSASRTQQPGLEVMAEIAGHHSVSEQEPPPNPAPAAPAPGEDDSGRLVGVLRRKGWLRRTRPTGPREEGNRVSALRPQEESVRFSFDYNSFRSRLRHPVLGTRTDESQESQSLVRAQREKIKEMMRFSWQSYRRYAMGKNELRPLTKDGFEGSMFGGLSGATIIDSLDTLYLMELKEEFQEAKAWVQDSFHLNVSGEASLFEVNIRYIGGLLSAFYLTGEEVFRVKAIKLGEKLLPAFNTPTGIPKGVVNFKSGSWGWATAGSSSILAEFGSLHLEFLHLTELSGNPIFAEKVLSGSCWQQAGGRLAELIPRHCSWLPKATRVRNIRKVLREIDKPFGLYPNFLSPVSGNWVQHHVSVGGLGDSFYEYLIKSWLMSAKTDMEAKTMYYEALEAIETYLVNVSPGGLTYIAEWRGGILDHKMGHLACFSGGMIALGAEDAKEDKRAYYRELAAQITRTCHESYARSDTKLGPEAFWFNSGREAVATQLSESYYILRPEVVESYMYLWRQTHDPIYREWGWEVVMALEKHCRTEGGFSGIQDVYSSNPNHDNRQQSFFLAETLKYLYLLFSEDDVLSLEDWVFNTEAHPLPVNRSDSSSVAGHRH", "length": 655 }, "evidence": [ { "id": "F1P0Z9", "url": "https://omabrowser.org/oma/group/F1P0Z9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E1B7B0-1", "protein_name": "alpha-1,2-Mannosidase", "gene_name": "MAN1C1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MLVRKVPGFVPASPWGLRLPQKFVFLLFLSGLVTLCFGALFLLPNSSRLKRLFLAPRTQQPGLEAVAQVASHPRARGQESPPNPAPAAPAPGKDDPGSQASSRRRKGWLRRTHPTGPREEATAARGGGATALRPQEGSVPSGFDFKAFRSRLRHPVLGTRTDRSKEPQSLVHTQREKIKEMMQFAWQSYKRYAMGKNELRPLTRDGYEGNMFGGLSGATVIDSLDTLYLMELKEEFQEAKAWVEESFHLNVSGEASLFEVNIRYIGGLLSAFYLTGDEVFRIKAIKLGEKLLPAFDTPTGIPKGVVNFKSGSNRSWGWAMAGSSSILAEFGSLHLEFLHLTQLSGNQVFAEKVRNIRKVLREIDKPFGLYPNFLSPVSGNWMQHHVSVGGLGDSFYEYLIKSWLMSAKTDMEAKDMYYEALEAIETHLVNVSPGGLTYIAEWRGGILDHKMGHLACFSGGMIALGAEDAKEEKRAHYRELAAQITKTCHESYARSDTKLGPEAFWFNSGREAVATQTSESYYILRPEVVESYMYLWRQTHDPIYREWGWEAVMALEKYCRTEAGFSGIQDVYSKVPNHDNRQQTFFLAETLKYLYLLFSEDDMLSLEDWVFNTEAHPLPVNHSDSSGRGGG", "length": 631 }, "evidence": [ { "id": "F1P0Z9", "url": "https://omabrowser.org/oma/group/F1P0Z9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q54PP9-1", "protein_name": "alpha-1,2-Mannosidase", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNPKIKLFLAIAIVAYLISIFTILSFDGRNKIDAQRFPDKWKIVIQNNNNNNYNNNNNKNYKKTGNPFNKIDEVYYQNEKLNIKRSEQVRGAMKHAWEKYKEFSWGQDELRPLTKSHKEWFGLGLTIIDSLDTLKIMNLDKEYKEGRDWVANVLKQSKNTGMTVSVFETIIRVLGSHVTMYGLTNDEMYLEKAVEIGDLLLYAFPEDTKKPFPSSNIRLATHGKSYPGWTGGCVILSEVSTLFLEFNELSRISGDPKYKEYSDRVIDALSKMKTSIPGLFPVFVNQDANGFCGSFITIGGLGDSYYEYLLKMWIYTNGEDEIYRRLFVESADSIIEHLYKVSPKGDGYLSAMDHNSLTNIQEHLACFAGGMFALAAAANITQDDKKSAKYMEVGEMITKTCVKTYLTSPSGLAPESFRVDPNSGNISWNVHGTYSFYILRPETVESLFILYRLTGDIKYQEWSWKIFEAIEDVCRHENGYNGLKNVDDRKSLDDTQESFFMAETLKYLYLSFQPSSVIPLDKYIFNTEAHPILIPKK", "length": 537 }, "evidence": [ { "id": "F1P0Z9", "url": "https://omabrowser.org/oma/group/F1P0Z9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q9C512-1", "protein_name": "Mannosyl-oligosaccharide 1,2-alpha-mannosidase MNS1", "gene_name": "MNS1", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MARSRSISGYGIWKYLNPAYYLRRPRRLALLFIVFVSVSMLVWDRINLAREHEVEVFKLNEEVSRLEQMLEELNGGVGNKPLKTLKDAPEDPVDKQRRQKVKEAMIHAWSSYEKYAWGKDELQPRTKDGTDSFGGLGATMVDSLDTLYIMGLDEQFQKAREWVASSLDFDKDYDASMFETTIRVVGGLLSAYDLSGDKMFLEKAKDIADRLLPAWNTPTGIPYNIINLRNGNAHNPSWAAGGDSILADSGTEQLEFIALSQRTGDPKYQQKVEKVITELNKNFPADGLLPIYINPDNANPSYSTTTFGAMGDSFYEYLLKVWVQGNKTSAVKPYRDMWEKSMKGLLSLVKKSTPSSFTYICEKNGNNLIDKMDELACFAPGMLALGASGYGPDEEKKFLSLAGELAWTCYNFYQSTPTKLAGENYFFTAGQDMSVGTSWNILRPETVESLFYLWRLTGNKTYQEWGWNIFQAFEKNSRVESGYVGLKDVNTGAKDNKMQSFFLAETLKYLYLLFSPSSVISLDEWVFNTEAHPLKIVARNDPRKPTIALRQRKFGHQINV", "length": 560 }, "evidence": [ { "id": "F1P0Z9", "url": "https://omabrowser.org/oma/group/F1P0Z9/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9NR34-1", "protein_name": "Mannosyl-oligosaccharide 1,2-alpha-mannosidase IC", "gene_name": "MAN1C1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLMRKVPGFVPASPWGLRLPQKFLFLLFLSGLVTLCFGALFLLPHSSRLKRLFLAPRTQQPGLEVVAEIAGHAPAREQEPPPNPAPAAPAPGEDDPSSWASPRRRKGGLRRTRPTGPREEATAARGNSIPASRPGDEGVPFRFDFNAFRSRLRHPVLGTRADESQEPQSQVRAQREKIKEMMQFAWQSYKRYAMGKNELRPLTKDGYEGNMFGGLSGATVIDSLDTLYLMELKEEFQEAKAWVGESFHLNVSGEASLFEVNIRYIGGLLSAFYLTGEEVFRIKAIRLGEKLLPAFNTPTGIPKGVVSFKSGNWGWATAGSSSILAEFGSLHLEFLHLTELSGNQVFAEKVRNIRKVLRKIEKPFGLYPNFLSPVSGNWVQHHVSVGGLGDSFYEYLIKSWLMSGKTDMEAKNMYYEALEAIETYLLNVSPGGLTYIAEWRGGILDHKMGHLACFSGGMIALGAEDAKEEKRAHYRELAAQITKTCHESYARSDTKLGPEAFWFNSGREAVATQLSESYYILRPEVVESYMYLWRQTHNPIYREWGWEVVLALEKYCRTEAGFSGIQDVYSSTPNHDNKQQSFFLAETLKYLYLLFSEDDLLSLEDWVFNTEAHPLPVNHSDSSGRAWGRH", "length": 630 }, "evidence": [ { "id": "F1P0Z9", "url": "https://omabrowser.org/oma/group/F1P0Z9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "F1P0Z9", "url": "https://www.uniprot.org/uniprotkb/F1P0Z9" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "F1P0Z9", "url": "https://www.uniprot.org/uniprotkb/F1P0Z9" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "F1P0Z9", "url": "https://www.uniprot.org/uniprotkb/F1P0Z9" } ], "pmid": "" }, { "name": "endomembrane system", "id": "GO:0012505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0012505", "evidence": [ { "database": "UniProtKB", "id": "F1P0Z9", "url": "https://www.uniprot.org/uniprotkb/F1P0Z9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "carbohydrate metabolic process", "id": "GO:0005975", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005975", "evidence": [ { "database": "UniProtKB", "id": "F1P0Z9", "url": "https://www.uniprot.org/uniprotkb/F1P0Z9" } ], "pmid": "" }, { "name": "ERAD pathway", "id": "GO:0036503", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036503", "evidence": [ { "database": "UniProtKB", "id": "F1P0Z9", "url": "https://www.uniprot.org/uniprotkb/F1P0Z9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "F1P0Z9", "url": "https://www.uniprot.org/uniprotkb/F1P0Z9" } ], "pmid": "" }, { "name": "mannosyl-oligosaccharide 1,2-alpha-mannosidase activity", "id": "GO:0004571", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004571", "evidence": [ { "database": "UniProtKB", "id": "F1P0Z9", "url": "https://www.uniprot.org/uniprotkb/F1P0Z9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 617, "end_pos": 619, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "56008", "name": "", "equation": "N(4)-(alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 9A1,2,3B1,2,3) + 4 H2O = N(4)-(alpha-D-Man-(1->3)-[alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 5A1,2) + 4 beta-D-mannose", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V1ABV1-1", "A0A1D5PEI6-1", "A0A8V0YQN0-1", "A0A8V0ZR18-1", "F1P0Z9-1" ], "evidence": [ { "id": "56008", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/56008" } ] }, { "id": "56028", "name": "", "equation": "N(4)-(alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 8A1,2,3B1,3) + 3 H2O = N(4)-(alpha-D-Man-(1->3)-[alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 5A1,2) + 3 beta-D-mannose", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V1ABV1-1", "A0A1D5PEI6-1", "A0A8V0YQN0-1", "A0A8V0ZR18-1", "F1P0Z9-1" ], "evidence": [ { "id": "56028", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/56028" } ] }, { "id": "R-GGA-964737", "name": "Progressive trimming of alpha-1,2-linked mannose residues from Man9GlcNAc2 to produce Man5GlcNAc2", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "Golgi lumen, Golgi membrane", "input_participant_list": [ "R-ALL-915149" ], "output_participant_list": [ "R-ALL-964740", "R-ALL-964752" ], "enzyme_list": [ "F1P0Z9-1", "A0A8V0YQN0-1", "A0A8V0ZR18-1" ], "evidence": [ { "id": "R-GGA-964737", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-964737" } ] }, { "id": "R-GGA-964825", "name": "Progressive trimming of alpha-1,2-linked mannose residues from Man8GlcNAc2 to produce Man5GlcNAc2", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "Golgi lumen, Golgi membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1P0Z9-1", "A0A8V0YQN0-1", "A0A8V0ZR18-1" ], "evidence": [ { "id": "R-GGA-964825", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-964825" } ] }, { "id": "R-GGA-964830", "name": "Progressive trimming of alpha-1,2-linked mannose residues from Man7GlcNAc2 to produce Man5GlcNAc2", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "Golgi lumen, Golgi membrane", "input_participant_list": [ "R-ALL-964828" ], "output_participant_list": [], "enzyme_list": [ "F1P0Z9-1", "A0A8V0YQN0-1", "A0A8V0ZR18-1" ], "evidence": [ { "id": "R-GGA-964830", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-964830" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-915149", "participant_name": "(GlcNAc)2 (Man)9 [Golgi lumen]", "crossref": [ { "id": "59092", "database": "ChEBI", "url": "" } ] }, { "participant_id": "R-ALL-964740", "participant_name": "(GlcNAc)2 (Man)5 (Asn)1 [Golgi lumen]", "crossref": [ { "id": "59087", "database": "ChEBI", "url": "" } ] }, { "participant_id": "R-ALL-964752", "participant_name": "Man [Golgi lumen]", "crossref": [ { "id": "4650", "database": "Guide to Pharmacology - Ligands", "url": "" }, { "id": "ZINC000003830679", "database": "ZINC", "url": "" }, { "id": "4208", "database": "ChEBI", "url": "" }, { "id": "G70323CJ", "database": "GlyTouCan", "url": "" }, { "id": "ZINC000003860903", "database": "ZINC", "url": "" }, { "id": "C00159", "database": "COMPOUND", "url": "" } ] }, { "participant_id": "R-ALL-964828", "participant_name": "(GlcNAc)2 (Man)7bc [Golgi lumen]", "crossref": [ { "id": "60637", "database": "ChEBI", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A0A1D5PEI6", "gene_name": "EDEM3", "activity": [ { "ec_number": "3.2.1.-", "activity": "", "evidence": [ { "id": "A0A1D5PEI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PEI6" } ] } ] }, { "uniprot_ac": "A0A8V0YQN0", "gene_name": "MAN1A1", "activity": [ { "ec_number": "3.2.1.-", "activity": "", "evidence": [ { "id": "A0A8V0YQN0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQN0" } ] } ] }, { "uniprot_ac": "A0A8V0ZR18", "gene_name": "MAN1A2", "activity": [ { "ec_number": "3.2.1.-", "activity": "", "evidence": [ { "id": "A0A8V0ZR18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR18" } ] } ] }, { "uniprot_ac": "A0A8V1ABV1", "gene_name": "MAN1B1", "activity": [ { "ec_number": "3.2.1.-", "activity": "", "evidence": [ { "id": "A0A8V1ABV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABV1" } ] } ] }, { "uniprot_ac": "F1P0Z9", "gene_name": "MAN1C1", "activity": [ { "ec_number": "3.2.1.-", "activity": "", "evidence": [ { "id": "F1P0Z9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P0Z9" } ] } ] } ], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1P0Z9-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 628, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1P0Z9-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1P0Z9" } ], "lectin_list": [], "domain_list": [], "binding_sites": [ { "evidence": [ { "id": "A0A8V0YZB4", 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Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052535.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_001233032", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001233032" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1P1G7", "url": "https://www.uniprot.org/uniprotkb/F1P1G7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "HTATSF1", "url": "https://www.uniprot.org/uniprotkb/F1P1G7", "locus": { "chromosome": "4", "start_pos": 4301979, "end_pos": 4288802, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010019961", "url": "https://www.ensembl.org/id/ENSGALG00010019961" } ] } } ], "crossref": [ { "id": "F1P1G7", "url": "https://alphafold.ebi.ac.uk/entry/F1P1G7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000006410", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000006410", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd12281", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12281", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd12282", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12282", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "422245", "url": "https://www.ncbi.nlm.nih.gov/gene/422245", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000504", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000504", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003954", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003954", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012677", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012677", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034392", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034392", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034393", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034393", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:422245", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422245", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DTDFRFG", "url": "https://omabrowser.org/oma/group/DTDFRFG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1P1G7", "url": "https://www.orthodb.org/?gene=F1P1G7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15608", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15608", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15608:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15608:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00076", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00076", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:F1P1G7", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:F1P1G7", "database": "PRO", "categories": [ "Protein" ] }, { "id": "R-GGA-9770562", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9770562", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_001233032", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001233032", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1P1G7", "url": "https://www.uniprot.org/uniprotkb/F1P1G7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1P1G7-1", "url": "https://www.uniprot.org/uniprotkb/F1P1G7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSGEDGNEEFYRQLQLQQQYEADRGGEGDADPFTYVDPADGAAYEWDREKKAWFPKITEDFLATYHANYGFNADETDSSSASGTASENKLPLSSKTSETQPSANEKGPKQTEPKQKTEKRKLEPGWFHVEEDRNTNVYVTGLPPDITKDEFVQVMSKGGIIMRDPQTEEHKIKLYKDKEGNLKGDGLCCYLKRESVQLALRLLDEAEIRGYKLHVEVAKFQLKGEYDASKKKKKCKDYKKKLSQQQKQLDWRPEKKDGAARMRHERIVIIRNMFHPKDFEEDPLVLNEIREDLRTECEKFGQVKKVLIFDRHPDGVASVSFKEATEADLCKLTLNGRWFGGRQLSAETWDGVTDYQVEETAREREERLKVWGSFLEDPDSKEQQTTSDSDSTTSSVKIPESSQPSKVNDASKEDVNDEGHKKENNGEGINEDGAPSTDSSLAGSDAEADT", "length": 450, "header": "tr|F1P1G7-1|F1P1G7_CHICK Isoform 1 of 17S U2 SnRNP complex component HTATSF1 OS=Gallus gallus OX=9031 GN=HTATSF1 PE=1 SV=1 CANONICAL=F1P1G7-1" }, "isoforms": [ { "isoform_ac": "F1P1G7-1", "url": "https://www.uniprot.org/uniprotkb/F1P1G7/entry#F1P1G7-1", "sequence": { "sequence": "MSGEDGNEEFYRQLQLQQQYEADRGGEGDADPFTYVDPADGAAYEWDREKKAWFPKITEDFLATYHANYGFNADETDSSSASGTASENKLPLSSKTSETQPSANEKGPKQTEPKQKTEKRKLEPGWFHVEEDRNTNVYVTGLPPDITKDEFVQVMSKGGIIMRDPQTEEHKIKLYKDKEGNLKGDGLCCYLKRESVQLALRLLDEAEIRGYKLHVEVAKFQLKGEYDASKKKKKCKDYKKKLSQQQKQLDWRPEKKDGAARMRHERIVIIRNMFHPKDFEEDPLVLNEIREDLRTECEKFGQVKKVLIFDRHPDGVASVSFKEATEADLCKLTLNGRWFGGRQLSAETWDGVTDYQVEETAREREERLKVWGSFLEDPDSKEQQTTSDSDSTTSSVKIPESSQPSKVNDASKEDVNDEGHKKENNGEGINEDGAPSTDSSLAGSDAEADT", "length": 450, "header": "tr|F1P1G7-1|F1P1G7_CHICK Isoform 1 of 17S U2 SnRNP complex component HTATSF1 OS=Gallus gallus OX=9031 GN=HTATSF1 PE=1 SV=1 CANONICAL=F1P1G7-1" }, "locus": { "chromosome": "4", "start_pos": 4299455, "end_pos": 4289010, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048200.1", "url": "https://www.ensembl.org/id/ENSGALT00010048200.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028424.1", "url": "https://www.ensembl.org/id/ENSGALP00010028424.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:422245", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422245", "resource": "KEGG Pathway" }, { "id": "R-GGA-9770562", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9770562", "resource": "Reactome", "description": "mRNA Polyadenylation" } ], "orthologs": [ { "uniprot_canonical_ac": "Q9LF02-1", "protein_name": "RNA binding (RRM/RBD/RNP motifs) family protein", "gene_name": "ELF9", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSDSDNLQLPPSSTGATVAATDVGWYILGENQQNLGPYTFSELCNHFRNGYLLETTLVWADGRSEWQPLSAIPDLMSRISGAEIAYPAVGSSGLINGSNAGTRQEKQDYTASASTEDEFEKWQREIKDAEAEAERLKNGSVSGTELVEDDHERASSPPEGEDEFTDDDGTKYKWDRARRVWVPQDDPPLGSVDPYGLEEMTFAKEDEVFPTINILDTSVDKKDASKDDVAGKKEEDGSDETAEINSNGKRKLPEPETEKKEPNKPPDSWFELKVNPHIYVNGLPDDVTIEEVAEVFSKCGIIKEDDTGKPRIKLYSDKATGKLKGDALISYMKEPSVDLAIKILDGAPLRPADKLLMSVSRAKFEQKGERFITKQTDNKKKKKLKKVEQKLLGWGGTDDSKVSIPATVVLRYMFSPAELMADEDLVAELEEDVKEESLKHGPFDSVKVCEHHPQGVVLVRFKDRRDAQKCIEAMNGRWYAKRQIHASLDDGSVNHATVRDFDLEAERLDQFAAELEAAE", "length": 519 }, "evidence": [ { "id": "F1P1G7", "url": "https://omabrowser.org/oma/group/F1P1G7/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "protein localization to site of double-strand break", "id": "GO:1990166", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990166", "evidence": [ { "database": "UniProtKB", "id": "F1P1G7", "url": "https://www.uniprot.org/uniprotkb/F1P1G7" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "F1P1G7", "url": "https://www.uniprot.org/uniprotkb/F1P1G7" } ], "pmid": "" }, { "name": "double-strand break repair via homologous recombination", "id": "GO:0000724", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000724", "evidence": [ { "database": "UniProtKB", "id": "F1P1G7", "url": "https://www.uniprot.org/uniprotkb/F1P1G7" } ], "pmid": "" }, { "name": "U2-type prespliceosome assembly", "id": "GO:1903241", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903241", "evidence": [ { "database": "UniProtKB", "id": "F1P1G7", "url": "https://www.uniprot.org/uniprotkb/F1P1G7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "F1P1G7", "url": "https://www.uniprot.org/uniprotkb/F1P1G7" } ], "pmid": "" }, { "name": "chromatin-protein adaptor activity", "id": "GO:0140463", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140463", "evidence": [ { "database": "UniProtKB", "id": "F1P1G7", "url": "https://www.uniprot.org/uniprotkb/F1P1G7" } ], "pmid": "" }, { "name": "poly-ADP-D-ribose modification-dependent protein binding", "id": "GO:0160004", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160004", "evidence": [ { "database": "UniProtKB", "id": "F1P1G7", "url": "https://www.uniprot.org/uniprotkb/F1P1G7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "F1P1G7", "url": "https://www.uniprot.org/uniprotkb/F1P1G7" } ], "pmid": "" }, { "name": "site of double-strand break", "id": "GO:0035861", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035861", "evidence": [ { "database": "UniProtKB", "id": "F1P1G7", "url": "https://www.uniprot.org/uniprotkb/F1P1G7" } ], "pmid": "" }, { "name": "U2 snRNP", "id": "GO:0005686", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005686", "evidence": [ { "database": "UniProtKB", "id": "F1P1G7", "url": "https://www.uniprot.org/uniprotkb/F1P1G7" } ], "pmid": "" }, { "name": "U2-type spliceosomal complex", "id": "GO:0005684", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005684", "evidence": [ { "database": "UniProtKB", "id": "F1P1G7", "url": "https://www.uniprot.org/uniprotkb/F1P1G7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1P1G7-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 450, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1P1G7-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1P1G7" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1P1G7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P1G7" }, { "id": "PS50102", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50102" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RRM", "eco_id": "ECO_0000259", "start_pos": 135, "end_pos": 220, "start_aa": "Thr", "end_aa": "Phe", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1P278-1", "uniprot_ac": "F1P278", "uniprot_id": "F1P278_CHICK", "mass": { "chemical_mass": 24072.0, "monoisotopic_mass": 24072.0 }, "refseq": { "ac": "NP_001264931", "name": "ras-related protein Rab-19", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264931" }, "gene_names": [ { "name": "RAB19", "type": "recommended", "evidence": [ { "id": "F1P278", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P278" } ] }, { "name": "RAB19", "type": "synonym", "evidence": [ { "id": "NP_001264931", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264931" } ] } ], "protein_names": [ { "name": "Ras-related protein Rab-19", "type": "recommended", "evidence": [ { "id": "F1P278", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P278/entry#names_and_taxonomy" } ] }, { "name": "3.6.5.2", "type": "synonym", "evidence": [ { "id": "F1P278", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P278/entry#names_and_taxonomy" } ] }, { "name": "ras-related protein Rab-19", "type": "synonym", "evidence": [ { "id": "NP_001264931", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264931" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: HAEK01099299.1, SRR13267661.25015.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000012.1. On May 5, 2013 this sequence version replaced XP_416347.1. Transcript Variant: This variant (1) represents the longer transcript. Variants 1 and 2 both encode the same protein. Sequence Note: This RefSeq record was created with transcript data from different strains to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001264931", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264931" } ] }, { "annotation": "The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion.", "evidence": [ { "database": "UniProtKB", "id": "F1P278", "url": "https://www.uniprot.org/uniprotkb/F1P278#function" }, { "database": "UniProtKB", "id": "ARBA00057434", "url": "https://www.uniprot.org/uniprotkb/ARBA00057434#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1P278", "url": "https://www.uniprot.org/uniprotkb/F1P278" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RAB19", "url": "https://www.uniprot.org/uniprotkb/F1P278", "locus": { "chromosome": "1", "start_pos": 56823867, "end_pos": 56816547, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013337", "url": "https://www.ensembl.org/id/ENSGALG00010013337" } ] } } ], "crossref": [ { "id": "F1P278", "url": "https://alphafold.ebi.ac.uk/entry/F1P278", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000012850", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000012850", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd01864", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01864", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "418113", "url": "https://www.ncbi.nlm.nih.gov/gene/418113", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001806", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001806", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005225", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005225", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048040", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048040", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050209", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050209", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:418113", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418113", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DMWEKRH", "url": "https://omabrowser.org/oma/group/DMWEKRH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1P278", "url": "https://www.orthodb.org/?gene=F1P278", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47979", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47979", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00071", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00071", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001264931", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264931", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "19669", "url": "https://www.rhea-db.org/rhea/19669", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "F1P278", "url": "https://www.uniprot.org/uniprotkb/F1P278", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1P278-1", "url": "https://www.uniprot.org/uniprotkb/F1P278-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPFSSSSADDAFDYLFKIILIGDSNVGKTCVVHRFKTGQFYEKQQNTIGVDFTVRSMDIDGKKVKIQVWDTAGQERFRTITQSYYRSAHGAILAYDLTRRSTFESIPHWVHEVEKYGAANLVMMLIGNKSDSVDKRQVLFEDACTLAEKYGLLAVLETSAKEAQNIEEVFVLMAKELIARNTLQLHGESPPNSVYLDSRPVITSPSAEKTQCLC", "length": 214, "header": "tr|F1P278-1|F1P278_CHICK Isoform 1 of Ras-related protein Rab-19 OS=Gallus gallus OX=9031 GN=RAB19 PE=1 SV=3 CANONICAL=F1P278-1" }, "isoforms": [ { "isoform_ac": "F1P278-1", "url": "https://www.uniprot.org/uniprotkb/F1P278/entry#F1P278-1", "sequence": { "sequence": "MPFSSSSADDAFDYLFKIILIGDSNVGKTCVVHRFKTGQFYEKQQNTIGVDFTVRSMDIDGKKVKIQVWDTAGQERFRTITQSYYRSAHGAILAYDLTRRSTFESIPHWVHEVEKYGAANLVMMLIGNKSDSVDKRQVLFEDACTLAEKYGLLAVLETSAKEAQNIEEVFVLMAKELIARNTLQLHGESPPNSVYLDSRPVITSPSAEKTQCLC", "length": 214, "header": "tr|F1P278-1|F1P278_CHICK Isoform 1 of Ras-related protein Rab-19 OS=Gallus gallus OX=9031 GN=RAB19 PE=1 SV=3 CANONICAL=F1P278-1" }, "locus": { "chromosome": "1", "start_pos": 56820104, "end_pos": 56816741, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032090.1", "url": "https://www.ensembl.org/id/ENSGALT00010032090.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018880.1", "url": "https://www.ensembl.org/id/ENSGALP00010018880.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "gga:418113", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418113", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8D0JFN3-1", "protein_name": "Ras-related protein Rab-19", "gene_name": "RAB19", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MQFSSSARAADENFDYLFKVILVGDSNVGKTCVVQHFKSGVYTEAQQNTIGVDFTVRALEIDGKKVKMQVWDTAGQERFRTITQSYYRSAHAAIIAYDLTRRSTFESVPHWIHEIEKYGAANLVIMLIGNKCDLWEKRHVLFEDACTLAEKYGLLAVLETSAKESKNIDEVFVLMARELIARNSLPLYAEGALSSLPLDSSPVLTVSPREKTQCTC", "length": 216 }, "evidence": [ { "id": "F1P278", "url": "https://omabrowser.org/oma/group/F1P278/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A4D1S5-1", "protein_name": "Ras-related protein Rab-19", "gene_name": "RAB19", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MHFSSSARAADENFDYLFKIILIGDSNVGKTCVVQHFKSGVYTETQQNTIGVDFTVRSLDIDGKKVKMQVWDTAGQERFRTITQSYYRSAHAAIIAYDLTRRSTFESIPHWIHEIEKYGAANVVIMLIGNKCDLWEKRHVLFEDACTLAEKYGLLAVLETSAKESKNIEEVFVLMAKELIARNSLHLYGESALNGLPLDSSPVLMAQGPSEKTHCTC", "length": 217 }, "evidence": [ { "id": "F1P278", "url": "https://omabrowser.org/oma/group/F1P278/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P35294-1", "protein_name": "Ras-related protein Rab-19", "gene_name": "Rab19", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MQFSSSSRTSDENVDYLFKVILIGDSNVGKTCVVQHFKSGVYSESQQNTIGVDFTVRSLEIDGKKVKMQVWDTAGQERFRTITQSYYRSAHAAIIAYDLTRRSTFESVPHWIHEIEKYGAANLVIMLIGNKSDLWEKRHVLFEDACTLAEKHGLLAVLETSAKESRNIDEVFVLMAKELIARNSLHLYGESAQQGLSQDSSPVLVAQVPNESTRCTC", "length": 217 }, "evidence": [ { "id": "F1P278", "url": "https://omabrowser.org/oma/group/F1P278/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q3ZC27-1", "protein_name": "Ras-related protein Rab-19", "gene_name": "RAB19", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MQFSSSARTVDENFDYLFKIILIGDSNVGKTCVVQHFKSGVYMEAQQNTIGVDFTVRALEIDGKKVKMQVWDTAGQERFRTITQSYYRSAHAAIIAYDLTRRSTFESVPHWIHEIEKYGAANLVIMLIGNKCDLWEKRHVLFEDACILAEKYGLLAVLETSAKESKNIDEVFVLMARELMARHSLPLYGEGAPGSLPLESTPVLMAPAPREKNQCTC", "length": 217 }, "evidence": [ { "id": "F1P278", "url": "https://omabrowser.org/oma/group/F1P278/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q5M7U5-1", "protein_name": "Ras-related protein Rab-19", "gene_name": "Rab19", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQFSSAARTVDENVDYLFKVILIGDSNVGKTCVVQHFKSGVYSESQQNTIGVDFTVRSLEIDGKKVKMQVWDTAGQERFRTITQSYYRSAHAAIIAYDLTRRSTFESVPHWIHEIEKYGAANLVIMLIGNKSDLWEKRHVLFEDACTLAEKYGLLAVLETSAKESRNIDEVFVLMAKELIARNSLHLYGESAQQGLPQDSSPVLVAHVPSERTHCTC", "length": 217 }, "evidence": [ { "id": "F1P278", "url": "https://omabrowser.org/oma/group/F1P278/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "autophagosome assembly", "id": "GO:0000045", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000045", "evidence": [ { "database": "UniProtKB", "id": "F1P278", "url": "https://www.uniprot.org/uniprotkb/F1P278" } ], "pmid": "" }, { "name": "intracellular protein transport", "id": "GO:0006886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006886", "evidence": [ { "database": "UniProtKB", "id": "F1P278", "url": "https://www.uniprot.org/uniprotkb/F1P278" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "GTPase activity", "id": "GO:0003924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003924", "evidence": [ { "database": "UniProtKB", "id": "F1P278", "url": "https://www.uniprot.org/uniprotkb/F1P278" } ], "pmid": "" }, { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "F1P278", "url": "https://www.uniprot.org/uniprotkb/F1P278" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "F1P278", "url": "https://www.uniprot.org/uniprotkb/F1P278" } ], "pmid": "" }, { "name": "G protein activity", "id": "GO:0003925", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003925", "evidence": [ { "database": "UniProtKB", "id": "F1P278", "url": "https://www.uniprot.org/uniprotkb/F1P278" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F1P278", "url": "https://www.uniprot.org/uniprotkb/F1P278" } ], "pmid": "" }, { "name": "endomembrane system", "id": "GO:0012505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0012505", "evidence": [ { "database": "UniProtKB", "id": "F1P278", "url": "https://www.uniprot.org/uniprotkb/F1P278" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 128, "end_pos": 130, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "19669", "name": "", "equation": "GTP + H2O = GDP + phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YVX9-1", "F1NSA8-1", "R4GJA4-1", "A0A1L1RKZ0-1", "E1BUS1-1", "Q5ZHW4-1", "Q90694-1", "P08070-1", "P09642-1", "P09643-1", "P09644-1", "P09645-1", "Q5F352-1", "Q5ZMS3-1", "Q90705-1", "Q90835-1", "Q90965-1", "Q98932-1", "A0A3Q2UHM4-1", "Q5ZHX1-1", "A0A1D5PT95-1", "E1BQI2-1", "F1NPF0-1", "A0A8V0XVU5-1", "A0A8V0XBX5-1", "A0A8V0Z564-1", "A0A8V0Y9R6-1", "A0A1D5PM27-1", "A0A8V0Z8U4-1", "A0A8V0ZJW2-1", "A0A8V1ABB1-1", "A0A8V0YDX6-1", "E1BWN3-1", "Q5F499-1", "Q5ZKU5-1", "P02552-1", "P08642-1", "P26990-1", "P42558-1", "Q5F470-1", "Q5ZIT5-1", "Q5ZJN2-1", "P50146-1", "A0A8V0ZNW3-1", "A0A8V0YIM0-1", "A0A8V0ZRZ2-1", "A0A8V1A9Z8-1", "Q1KME6-1", "Q5ZLG1-1", "P84172-1", "A0A8V1ACG4-1", "A0A8V0YTL7-1", "A0A3Q2UG55-1", "A0A8V1AIF5-1", "Q5ZHV1-1", "A0A8V0Z5P2-1", "A0A8V0Y4A4-1", "A0A8V0YA62-1", "A0A8V0YVM3-1", "A0A1D5P1F5-1", "A0A8V1ADZ7-1", "F1NWF1-1", "A0A8V1AP30-1", "A0A8V0XDD5-1", "A0A8V0XMC5-1", "A0A8V0YWW1-1", "A0A8V0ZR14-1", "A0A8V0Y2H3-1", "Q5ZJD3-1", "Q5ZM73-1", "Q5ZM83-1", "A0A8V0YTY9-1", "A0A8V0ZXW3-1", "A0A8V1AHB3-1", "A0A8V0YDI7-1", "A0A1D5NV13-1", "A0A8V0XGK7-1", "A0A8V0YHK2-1", "A0A8V0XC33-1", "A0A8V0XKC3-1", "F1P278-1", "A0A8V0ZG00-1", "A0A8V1AGP3-1", "A0A8V1AN75-1", "A0A8V0Z416-1", "A0A8V1A0V4-1", "A0A8V1A8Q7-1", "A0A8V1ABD3-1", "A0A8V1API8-1", "A0A8V0YIU8-1", "A0A8V0X962-1", "A0A8V1AKH3-1", "P79784-1", "A0A1D5P533-1", "A0A8V1A8I5-1", "A0A8V1AE09-1", "Q9PSX7-1", "Q5ZKR4-1", "A0A8V0YGN8-1", "A0A8V0XNL0-1", "A0A8V0Y3H2-1" ], "evidence": [ { "id": "19669", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/19669" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A1D5NV13", "gene_name": "RIT2", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5NV13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NV13" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A1D5NV13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NV13" } ] } ] }, { "uniprot_ac": "A0A1D5P1F5", "gene_name": "RAB40C", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5P1F5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P1F5" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A1D5P1F5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P1F5" } ] } ] }, { "uniprot_ac": "A0A1D5P533", "gene_name": "RASEF", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5P533", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P533" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A1D5P533", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P533" } ] } ] }, { "uniprot_ac": "A0A1D5PM27", "gene_name": "OPA1", "activity": [ { "ec_number": "3.6.5.5", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5PM27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PM27" } ] }, { "ec_number": "3.6.5.5", "activity": "", "evidence": [ { "id": "A0A1D5PM27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PM27" } ] } ] }, { "uniprot_ac": "A0A1D5PT95", "gene_name": "KRAS", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5PT95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PT95" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A1D5PT95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PT95" } ] } ] }, { "uniprot_ac": "A0A1L1RKZ0", "gene_name": "RASL11AL", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A1L1RKZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RKZ0" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A1L1RKZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RKZ0" } ] } ] }, { "uniprot_ac": "A0A3Q2UG55", "gene_name": "RAB9B", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q2UG55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UG55" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A3Q2UG55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UG55" } ] } ] }, { "uniprot_ac": "A0A3Q2UHM4", "gene_name": "DNM1L", "activity": [ { "ec_number": "3.6.5.5", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q2UHM4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UHM4" } ] }, { "ec_number": "3.6.5.5", "activity": "", "evidence": [ { "id": "A0A3Q2UHM4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UHM4" } ] } ] }, { "uniprot_ac": "A0A8V0X962", "gene_name": "RAB31", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0X962", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X962" } ] }, { 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"F1P2A4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P2A4" } ] }, { "name": "BET1L", "type": "synonym", "evidence": [ { "id": "NP_001026344", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026344" } ] } ], "protein_names": [ { "name": "BET1-like protein", "type": "recommended", "evidence": [ { "id": "F1P2A4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P2A4/entry#names_and_taxonomy" } ] }, { "name": "BET1-like protein", "type": "synonym", "evidence": [ { "id": "NP_001026344", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026344" } ] }, { "name": "blocked early in transport 1 homolog-like", "type": "synonym", "evidence": [ { "id": "NP_001026344", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026344" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ719590.1, HAEK01036101.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000212.1. On Nov 15, 2007 this sequence version replaced NP_001026344.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001026344", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026344" } ] }, { "annotation": "Vesicle SNARE required for targeting and fusion of retrograde transport vesicles with the Golgi complex. Required for the integrity of the Golgi complex.", "evidence": [ { "database": "UniProtKB", "id": "F1P2A4", "url": "https://www.uniprot.org/uniprotkb/F1P2A4#function" }, { "database": "UniProtKB", "id": "ARBA00037250", "url": "https://www.uniprot.org/uniprotkb/ARBA00037250#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1P2A4", "url": "https://www.uniprot.org/uniprotkb/F1P2A4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "BET1L", "url": "https://www.uniprot.org/uniprotkb/F1P2A4", "locus": { "chromosome": "5", "start_pos": 1828392, "end_pos": 1824011, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010020936", "url": "https://www.ensembl.org/id/ENSGALG00010020936" } ] } } ], "crossref": [ { "id": "F1P2A4", "url": "https://alphafold.ebi.ac.uk/entry/F1P2A4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000004172", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000004172", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd15853", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15853", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "422985", "url": "https://www.ncbi.nlm.nih.gov/gene/422985", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000727", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000727", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039899", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039899", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:422985", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422985", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "RLMCYLI", "url": "https://omabrowser.org/oma/group/RLMCYLI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1P2A4", "url": "https://www.orthodb.org/?gene=F1P2A4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12791", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12791", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "NP_001026344", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026344", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1P2A4", "url": "https://www.uniprot.org/uniprotkb/F1P2A4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1P2A4-1", "url": "https://www.uniprot.org/uniprotkb/F1P2A4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MADWGRGQNAVAMEDMLDVENKRMADSLASKVTRLKSLALDIDKDADEQNRYLDGMDSDFMSVTGLLTGSVKRFTTMTRSGRENRKLLCFVSIGLIVVFFILYYLVSKAGT", "length": 111, "header": "tr|F1P2A4-1|F1P2A4_CHICK Isoform 1 of BET1-like protein OS=Gallus gallus OX=9031 GN=BET1L PE=1 SV=2 CANONICAL=F1P2A4-1" }, "isoforms": [ { "isoform_ac": "F1P2A4-1", "url": "https://www.uniprot.org/uniprotkb/F1P2A4/entry#F1P2A4-1", "sequence": { "sequence": "MADWGRGQNAVAMEDMLDVENKRMADSLASKVTRLKSLALDIDKDADEQNRYLDGMDSDFMSVTGLLTGSVKRFTTMTRSGRENRKLLCFVSIGLIVVFFILYYLVSKAGT", "length": 111, "header": "tr|F1P2A4-1|F1P2A4_CHICK Isoform 1 of BET1-like protein OS=Gallus gallus OX=9031 GN=BET1L PE=1 SV=2 CANONICAL=F1P2A4-1" }, "locus": { "chromosome": "5", "start_pos": 1825740, "end_pos": 1824067, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050593.1", "url": "https://www.ensembl.org/id/ENSGALT00010050593.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029866.1", "url": "https://www.ensembl.org/id/ENSGALP00010029866.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:422985", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422985", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "F1RGD1-1", "protein_name": "BET1-like protein", "gene_name": "BET1L", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MADWARAQSPGAVEEILDRENKRMADTLASKVTRLKSLALDIDRDVEDQNRYLDGMDSDFTSVTGLLTGSVKRFSTMARSGRDNRKLLCGVAMGLIVVFFILSYLLSRART", "length": 111 }, "evidence": [ { "id": "F1P2A4", "url": "https://omabrowser.org/oma/group/F1P2A4/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "O35152-1", "protein_name": "BET1-like protein", "gene_name": "Bet1l", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MADWTRAQSSGAVEEIVDRENKRMADSLASKVTRLKSLALDIDRDTEDQNRYLDGMDSDFTSVTGLLTGSVKRFSTVARSGRDTRKLLCGMAVVLIVAFFILSYLFSRTRT", "length": 111 }, "evidence": [ { "id": "F1P2A4", "url": "https://omabrowser.org/oma/group/F1P2A4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O35153-1", "protein_name": "BET1-like protein", "gene_name": "Bet1l", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MADWTRAQSSGAVEDILDRENKRMADSLASKVTRLKSLALDIDRDTEDQNRYLDGMDSDFTSVTGLLTGSVKRFSTMARSGRDNRKLLCGMAVVLIVAFFILSYLLSRTRT", "length": 111 }, "evidence": [ { "id": "F1P2A4", "url": "https://omabrowser.org/oma/group/F1P2A4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q3MHP8-1", "protein_name": "BET1-like protein", "gene_name": "BET1L", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MADWARAQSPGAVEEILDRENKRMADSLASKVTRLKSLALDIDRDAEDQNRYLDGMDSDFTSMTGLLTGSVKRFSTMARSGRDNRKLLCGVAVGLIVAFFILSYLLSRART", "length": 111 }, "evidence": [ { "id": "F1P2A4", "url": "https://omabrowser.org/oma/group/F1P2A4/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q68EL3-1", "protein_name": "BET1-like protein", "gene_name": "bet1l", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MADPWNRGHGAVDDMLDAENKRMAENLASKVSRLKSLAYDIDKDAEEQNAYLDGMDSNFLSATGLLTGSVKRFSTMVRSGRDNRKILCYVSVGLVVAFFLLYYLVSRMQN", "length": 110 }, "evidence": [ { "id": "F1P2A4", "url": "https://omabrowser.org/oma/group/F1P2A4/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q9M2J9-1", "protein_name": "Bet1-like SNARE 1-1", "gene_name": "BET11", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MNPRREPRGGRSSLFDGIEEGGIRAASSYSHEINEHENERALEGLQDRVILLKRLSGDINEEVDTHNRMLDRMGNDMDSSRGFLSGTMDRFKTVFETKSSRRMLTLVASFVGLFLVIYYLTR", "length": 122 }, "evidence": [ { "id": "F1P2A4", "url": "https://omabrowser.org/oma/group/F1P2A4/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9NYM9-1", "protein_name": "BET1-like protein", "gene_name": "BET1L", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MADWARAQSPGAVEEILDRENKRMADSLASKVTRLKSLALDIDRDAEDQNRYLDGMDSDFTSMTSLLTGSVKRFSTMARSGQDNRKLLCGMAVGLIVAFFILSYFLSRART", "length": 111 }, "evidence": [ { "id": "F1P2A4", "url": "https://omabrowser.org/oma/group/F1P2A4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "F1P2A4", "url": "https://www.uniprot.org/uniprotkb/F1P2A4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "F1P2A4", "url": "https://www.uniprot.org/uniprotkb/F1P2A4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1P2A4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P2A4" }, { "id": "PS50192", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50192" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "T-SNARE coiled-coil homology", "eco_id": "ECO_0000259", "start_pos": 15, "end_pos": 77, "start_aa": "Asp", "end_aa": "Met", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1P2A7-1", "uniprot_ac": "F1P2A7", "uniprot_id": "F1P2A7_CHICK", "mass": { "chemical_mass": 103965.0, "monoisotopic_mass": 103965.0 }, "refseq": { "ac": "NP_001006376", "name": "exocyst complex component 2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006376" }, "gene_names": [ { "name": "EXOC2", "type": "recommended", "evidence": [ { "id": "F1P2A7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P2A7" } ] }, { "name": "EXOC2", "type": "synonym", "evidence": [ { "id": "NP_001006376", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006376" } ] } ], "protein_names": [ { "name": "Exocyst complex component 2", "type": "recommended", "evidence": [ { "id": "F1P2A7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P2A7/entry#names_and_taxonomy" } ] }, { "name": "exocyst complex component 2", "type": "synonym", "evidence": [ { "id": "NP_001006376", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006376" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: SRR13267656.28770.1, SRR13267649.173711.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA103992290, SAMEA103992323 [ECO:0006172] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000040.1. On Oct 20, 2010 this sequence version replaced NP_001006376.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments of chick cDNAs and orthologous human NP_060773.3.", "evidence": [ { "database": "RefSeq", "id": "NP_001006376", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006376" } ] }, { "annotation": "Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Y9X8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9X8#function" }, { "database": "UniProtKB", "id": "ARBA00002660", "url": "https://www.uniprot.org/uniprotkb/ARBA00002660#function" }, { "database": "UniProtKB", "id": "RU365069", "url": "https://www.uniprot.org/uniprotkb/RU365069#function" }, { "database": "UniProtKB", "id": "A0A8V0Y570", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y570#function" }, { "database": "UniProtKB", "id": "A0A8V0YBE9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBE9#function" }, { "database": "UniProtKB", "id": "A0A8V0YDM9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDM9#function" }, { "database": "UniProtKB", "id": "A0A8V0YIC3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIC3#function" }, { "database": "UniProtKB", "id": "F1P2A7", "url": "https://www.uniprot.org/uniprotkb/F1P2A7#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1P2A7", "url": "https://www.uniprot.org/uniprotkb/F1P2A7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "EXOC2", "url": "https://www.uniprot.org/uniprotkb/F1P2A7", "locus": { "chromosome": "2", "start_pos": 66236456, "end_pos": 66467522, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010011509", "url": "https://www.ensembl.org/id/ENSGALG00010011509" } ] } } ], "crossref": [ { "id": "F1P2A7", "url": "https://alphafold.ebi.ac.uk/entry/F1P2A7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000012837", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000012837", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00603", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00603", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "420889", "url": "https://www.ncbi.nlm.nih.gov/gene/420889", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002909", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002909", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014756", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014756", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029175", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029175", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039481", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039481", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:420889", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420889", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "RMWMDVD", "url": "https://omabrowser.org/oma/group/RMWMDVD/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y570", "url": "https://www.orthodb.org/?gene=A0A8V0Y570", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y9X8", "url": "https://www.orthodb.org/?gene=A0A8V0Y9X8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YBE9", "url": "https://www.orthodb.org/?gene=A0A8V0YBE9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YDM9", "url": "https://www.orthodb.org/?gene=A0A8V0YDM9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YIC3", "url": "https://www.orthodb.org/?gene=A0A8V0YIC3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1P2A7", "url": "https://www.orthodb.org/?gene=F1P2A7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13043", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13043", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13043:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13043:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01833", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01833", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF15469", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15469", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-264876", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-264876", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-5620916", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5620916", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001006376", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006376", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Y570", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y570", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y570-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y570-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y9X8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9X8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y9X8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9X8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YBE9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBE9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YBE9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBE9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YDM9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDM9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YDM9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDM9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YIC3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIC3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YIC3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIC3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1P2A7", "url": "https://www.uniprot.org/uniprotkb/F1P2A7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1P2A7-1", "url": "https://www.uniprot.org/uniprotkb/F1P2A7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSRARQPPLVTGISPNEGISWTKVTIRGENLGTGPTDLIGLTICGHNCLLTAEWMSASKIVCRVGQAKNDKGDIIVTTKSGGRGTSTVSFKLLKPEKIGILDQSAVWVDEMNYYDMRTDRNKGIPPLSLRPANPLGIEIDKGRFPQKDLETLFPGMSADFTSENFSAAWYLIENHSTASFDQLKMAVVNLKKQANKKSEGSLAYVKGGLSTFFEAQDALSAIHQKLEADGTEKVEGSMTQKLENVLNRASNTADTLFQEVLGRKDKADSTRNALNVLQRFKFLFNLPLNIERNIQKGDYDVVINDYEKAKSLFGKTEVQVFKKYYAEVETRIEALRELLLDKLLETPSTLHDQKRYIRYLSDLHAPGDPAWQCIGAQHQWILQLMHNCKESYVKEQKGTSLLHSSMLDLDSDVRPSPIGHLSQTASLKRGSSFQSGRNDAWRYKAPQQVVFVEKLTKLVVSQLPNFWKLWISYVNGSLFSETAEKSGQMEKSKKNARQRQNDFKKMIQEVMHSLEKLIRGALLPFSLKEGESRQYGGWEMKSELSGQWLTHVIQTVRLSSESLTALEIPNDMLQIIQDLILDLRVRCIIVTLQHTAEDIKRLAEKEDWVVDNEGLTSLPSHFEQCIVHSLQSLKTVLDCKPGEASVFQQQKIQEDVCQLSIGILQVFIDCLEQLSTKPDGDIDTSHLSVDVSSPDLFGSIHEDSSLTSEQRVLIALSNCRYLERHTFLNIAEHFEKHGFQGVDKITQVSMESLKELDQRLFEMYIESKADPIVGSLEPGIYAGYFDWKDCLVPAGVRNYLKEALVNIIAVHAEVFTISKDLVPRVMSRIVEAVSEELSRLMQCVSSFSKNGALQARLEICALRDTVAIYLTPESNSSFKQALEALPQLSSGADKKLLEELLNKFKSSMHLQLTCFQTSSSAMIKT", "length": 925, "header": "tr|F1P2A7-1|F1P2A7_CHICK Isoform 1 of Exocyst complex component 2 OS=Gallus gallus OX=9031 GN=EXOC2 PE=1 SV=3 CANONICAL=F1P2A7-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Y570-1", "url": "https://www.uniprot.org/uniprotkb/F1P2A7/entry#A0A8V0Y570-1", "sequence": { "sequence": "MSRARQPPLVTGISPNEGISWTKVTIRGENLGTGPTDLIGLTICGHNCLLTAEWMSASKIVCRVGQAKNDKGDIIVTTKSGGRGTSTVSFKLLKPEKIGILDQSAVWVDEMNYYDMRTDRNKGIPPLSLRPANPLGIEIDKGRFPQKDLETLFPGMSADFTSENFSAAWYLIENHSTARFVAII", "length": 184, "header": "tr|A0A8V0Y570-1|A0A8V0Y570_CHICK Computationally mapped isoform of Exocyst complex component 2 OS=Gallus gallus OX=9031 GN=EXOC2 PE=1 SV=1 CANONICAL=F1P2A7-1" }, "locus": { "chromosome": "2", "start_pos": 66353085, "end_pos": 66336382, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027553.1", "url": "https://www.ensembl.org/id/ENSGALT00010027553.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015781.1", "url": "https://www.ensembl.org/id/ENSGALP00010015781.1" } ] } }, { "isoform_ac": "A0A8V0Y9X8-1", "url": "https://www.uniprot.org/uniprotkb/F1P2A7/entry#A0A8V0Y9X8-1", "sequence": { "sequence": "MSRARQPPLVTGISPNEGISWTKVTIRGENLGTGPTDLIGLTICGHNCLLTAEWMSASKIVCRVGQAKNDKGDIIVTTKSGGRGTSTVSFKLLKPEKIGILDQSAVWVDEMNYYDMRTDRNKGIPPLSLRPANPLGIEIDKGRFPQKDLETLFPGMSADFTSENFSAAWYLIENHSTASSLKGSTILQIYFIV", "length": 193, "header": "tr|A0A8V0Y9X8-1|A0A8V0Y9X8_CHICK Computationally mapped isoform of Exocyst complex component 2 OS=Gallus gallus OX=9031 GN=EXOC2 PE=1 SV=1 CANONICAL=F1P2A7-1" }, "locus": { "chromosome": "2", "start_pos": 66353085, "end_pos": 66335702, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027561.1", "url": "https://www.ensembl.org/id/ENSGALT00010027561.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015785.1", "url": "https://www.ensembl.org/id/ENSGALP00010015785.1" } ] } }, { "isoform_ac": "A0A8V0YBE9-1", "url": "https://www.uniprot.org/uniprotkb/F1P2A7/entry#A0A8V0YBE9-1", "sequence": { "sequence": "MSRARQPPLVTGISPNEGISWTKVTIRGENLGTGPTDLIGLTICGHNCLLTAEWMSASKIVCRVGQAKNDKGDIIVTTKSGGRGTSTVSFKLLKPEKIGILDQSAVWVDEMNYYDMRTDRNKGIPPLSLRPANPLGIEIDKGRFPQKDLETLFPGMSADFTSENFSAAWYLIENHSTASFDQLKMAVVNLKKQANKKSEGSLAYVKGGLSTFFEAQDALSGCPSAAICHIATK", "length": 233, "header": "tr|A0A8V0YBE9-1|A0A8V0YBE9_CHICK Computationally mapped isoform of Exocyst complex component 2 OS=Gallus gallus OX=9031 GN=EXOC2 PE=1 SV=1 CANONICAL=F1P2A7-1" }, "locus": { "chromosome": "2", "start_pos": 66353085, "end_pos": 66330261, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027555.1", "url": "https://www.ensembl.org/id/ENSGALT00010027555.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015783.1", "url": "https://www.ensembl.org/id/ENSGALP00010015783.1" } ] } }, { "isoform_ac": "A0A8V0YDM9-1", "url": "https://www.uniprot.org/uniprotkb/F1P2A7/entry#A0A8V0YDM9-1", "sequence": { "sequence": "MSRARQPPLVTGISPNEGISWTKVTIRGENLGTGPTDLIGLTICGHNCLLTAEWMSASKIVCRVGQAKNDKGDIIVTTKSGGRGTSTVSFKLLKPEKIGILDQSAVWVDEMNYYDMRTDRNKGIPPLSLRPANPLGIEIDKGRFPQKDLETLFPGMSADFTSENFSAAWYLIENHSTASFDQLKMAVVNLKKQANKKSEGSLAYVKGGLSTFFEAQDALSAIHQKLEADGTEKVEGSMTQKLENVLNRASNTADTLFQEVLGRKDKADSTRNALNVLQRFKFLFNLPLNIERNIQKGDYDVVINDYEKAKSLFGKTEVQVFKKYYAEVETRIEALRELLLDKLLETPSTLHDQKRYIRYLSDLHAPGDPAWQCIGAQHQWILQLMHNCKESYVKEQKGTSLLHSSMLDLDSDVRPSPIGHLSQTASLKRGSSFQSGRNDAWRYKAPQQVVFVEKLTKLVVSQLPNFWKLWISYVNGSLFSETAEKSGQMEKSKKNARQRQNDFKKMIQEVMHSLEKLIRGALLPFSLKEGESRQYGGWEMKSELSGQWLTHVIQTVRLSSESLTALEIPNDMLQIIQDLILDLRVRCIIVTLQHTAEDIKRLAEKEDWVVDNEGLTSLPSHFEQCIVHSLQSLKTVLDCKPGEASVFQQQKIQEDVCQLSIGILQVFIDCLEQLSTKPDGDIDTSHLSVDVSSPDLFGSIHEDSSLTSEQRVLIALSNCRYLERHTFLNIAEHFEKHGFQGVDKITQVSMESLKELDQRLFEMYIESKADPIVGSLEPGIYAGYFDWKDCLVPAGVRNYLKEALVNIIAVHAEVFTISKDLVPRVMSRIVEAVSEELSRLMQCVSSFSKNGALQAVNSSMGVI", "length": 863, "header": "tr|A0A8V0YDM9-1|A0A8V0YDM9_CHICK Computationally mapped isoform of Exocyst complex component 2 OS=Gallus gallus OX=9031 GN=EXOC2 PE=1 SV=1 CANONICAL=F1P2A7-1" }, "locus": { "chromosome": "2", "start_pos": 66353085, "end_pos": 66243255, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027559.1", "url": "https://www.ensembl.org/id/ENSGALT00010027559.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015784.1", "url": "https://www.ensembl.org/id/ENSGALP00010015784.1" } ] } }, { "isoform_ac": "A0A8V0YIC3-1", "url": "https://www.uniprot.org/uniprotkb/F1P2A7/entry#A0A8V0YIC3-1", "sequence": { "sequence": "MSRARQPPLVTGISPNEGISWTKVTIRGENLGTGPTDLIGLTICGHNCLLTAEWMSASKIVCRVGQAKNDKGDIIVTTKSGGRGTSTVSFKLLKPEKIGILDQSAVWVDEMNYYDMRTDRNKGIPPLSLRPANPLGIEIDKGRFPQKDLETLFPGMSADFTSENFSAAWYLIENHSTASFDQLKMAVVNLKKQANKKSEGSLAYVKGGLSTFFEAQDALSAIHQKLEADGTEKVEGSMTQKLENVLNRASNTADTLFQEVLGRKDKADSTRNALNVLQRFKFLFNLPLNIERNIQKGDYDVVINDYEKAKSLFGKTEVQVFKKYYAEVETRIEALRELLLDKLLETPSTLHDQKRYIRYLSDLHAPGDPAWQCIGAQHQWILQLMHNCKESYVKEQKAWRYKAPQQVVFVEKLTKLVVSQLPNFWKLWISYVNGSLFSETAEKSGQMEKSKKNARQRQNDFKKMIQEVMHSLEKLIRGALLPFSLKEGESRQYGGWEMKSELSGQWLTHVIQTVRLSSESLTALEIPNDMLQIIQDLILDLRVRCIIVTLQHTAEDIKRLAEKEDWVVDNEGLTSLPSHFEQCIVHSLQSLKTVLDCKPGEASVFQQQKIQEDVCQLSIGILQVFIDCLEQLSTKPDGDIDTSHLSVDVSSPDLFGSIHEDSSLTSEQRVLIALSNCRYLERHTFLNIAEHFEKHGFQGVDKITQVSMESLKELDQRLFEMYIESKADPIVGSLEPGIYAGYFDWKDCLVPAGVRNYLKEALVNIIAVHAEVFTISKDLVPRVMSRIVEAVSEELSRLMQCVSSFSKNGALQARLEICALRDTVAIYLTPESNSSFKQALEALPQLSSGADKKLLEELLNKFKSSMHLQLTCFQTSSSAMIKT", "length": 883, "header": "tr|A0A8V0YIC3-1|A0A8V0YIC3_CHICK Computationally mapped isoform of Exocyst complex component 2 OS=Gallus gallus OX=9031 GN=EXOC2 PE=1 SV=1 CANONICAL=F1P2A7-1" }, "locus": { "chromosome": "2", "start_pos": 66353085, "end_pos": 66238039, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027565.1", "url": "https://www.ensembl.org/id/ENSGALT00010027565.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015787.1", "url": "https://www.ensembl.org/id/ENSGALP00010015787.1" } ] } }, { "isoform_ac": "F1P2A7-1", "url": "https://www.uniprot.org/uniprotkb/F1P2A7/entry#F1P2A7-1", "sequence": { "sequence": "MSRARQPPLVTGISPNEGISWTKVTIRGENLGTGPTDLIGLTICGHNCLLTAEWMSASKIVCRVGQAKNDKGDIIVTTKSGGRGTSTVSFKLLKPEKIGILDQSAVWVDEMNYYDMRTDRNKGIPPLSLRPANPLGIEIDKGRFPQKDLETLFPGMSADFTSENFSAAWYLIENHSTASFDQLKMAVVNLKKQANKKSEGSLAYVKGGLSTFFEAQDALSAIHQKLEADGTEKVEGSMTQKLENVLNRASNTADTLFQEVLGRKDKADSTRNALNVLQRFKFLFNLPLNIERNIQKGDYDVVINDYEKAKSLFGKTEVQVFKKYYAEVETRIEALRELLLDKLLETPSTLHDQKRYIRYLSDLHAPGDPAWQCIGAQHQWILQLMHNCKESYVKEQKGTSLLHSSMLDLDSDVRPSPIGHLSQTASLKRGSSFQSGRNDAWRYKAPQQVVFVEKLTKLVVSQLPNFWKLWISYVNGSLFSETAEKSGQMEKSKKNARQRQNDFKKMIQEVMHSLEKLIRGALLPFSLKEGESRQYGGWEMKSELSGQWLTHVIQTVRLSSESLTALEIPNDMLQIIQDLILDLRVRCIIVTLQHTAEDIKRLAEKEDWVVDNEGLTSLPSHFEQCIVHSLQSLKTVLDCKPGEASVFQQQKIQEDVCQLSIGILQVFIDCLEQLSTKPDGDIDTSHLSVDVSSPDLFGSIHEDSSLTSEQRVLIALSNCRYLERHTFLNIAEHFEKHGFQGVDKITQVSMESLKELDQRLFEMYIESKADPIVGSLEPGIYAGYFDWKDCLVPAGVRNYLKEALVNIIAVHAEVFTISKDLVPRVMSRIVEAVSEELSRLMQCVSSFSKNGALQARLEICALRDTVAIYLTPESNSSFKQALEALPQLSSGADKKLLEELLNKFKSSMHLQLTCFQTSSSAMIKT", "length": 925, "header": "tr|F1P2A7-1|F1P2A7_CHICK Isoform 1 of Exocyst complex component 2 OS=Gallus gallus OX=9031 GN=EXOC2 PE=1 SV=3 CANONICAL=F1P2A7-1" }, "locus": { "chromosome": "2", "start_pos": 66353085, "end_pos": 66238039, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027563.1", "url": "https://www.ensembl.org/id/ENSGALT00010027563.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015786.1", "url": "https://www.ensembl.org/id/ENSGALP00010015786.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:420889", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420889", "resource": "KEGG Pathway" }, { "id": "R-GGA-264876", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-264876", "resource": "Reactome", "description": "Insulin processing" }, { "id": "R-GGA-5620916", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5620916", "resource": "Reactome", "description": "VxPx cargo-targeting to cilium" } ], "orthologs": [ { "uniprot_canonical_ac": "E1BDW9-1", "protein_name": "Exocyst complex component 2", "gene_name": "EXOC2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSRSRQPPLVTGISPNEGIPWTKVTIRGENLGTGPADLIGLTICGHNCLLTAEWMSASKIVCRVGQAKNDKGDIIVTTKSGGKGTSTVSFKLLKPEKIGILDQSAVWVDEMNYYDMRTDRNKGIPPLSLRPANPLGIEIEKGKFPQKDLEMLFPGMSADFTSENFSAAWYLIENHSNTSFEQLKMAITHLKRQANKKSEGSLAYVKGGLSTFFEAQDALSAIHQKLEADGTEKVEGSMTQKLENVLNRASNTADTLFQEVLGRKDKADSTRNALNVLQRFKFLFNLPLNIERNIQKGDYDVVINDYEKAKSLFGKTEVQVFKKYYAEVETRIEALRELLLEKLLETPSTLHDQKRYIRYLSDLHAPGDPAWQCIGAQHRWILQLMHGCREGCVRDLKGPPGLHSTSLDLDAEVRASAPSHLGQTASLKRGSSFQPGRDDAWRCKTPHRVAFVEKLTKLVLSQLPNFWKLWISYVNGSLFSETAEKSGHIERSKNVRQRQNDFKKMIQEVMQCLVKLVRGALLPLGAAEGSGRQLGGWEGKAELSGPWLAHVIQTLRLTYESLAALEIPNDLLQTIQDLVLDLRVRCVLVTLQHTAEDIKRLAEKEDWVVDSEGLTSLPCRFERCVVLSLQSLRGVLECKPGEASVFQHPKTQEEVCQLSINIMQVFIYCLEQLSTKPDADVDTAHLSVDVSSPDLFGSIHEDFSLTSEQRLLIVLSNCCYLERHTFLNIAEHFEKHNFQGIEKITQVSMASLKDLDQRLFESYIELKADPIVGSLEPGIYAGYFDWRDCLPPTGVRNYLKEALVNIIAVHAEVFTVSKDLVPRVLSRVVEAVSEELSRLMQCVSSFSRNGALQARLEICTLRDTVAAHLTLESRSSFKQALEALPQLSSGADRKLLEELLSRVKSGMHLQLACFQAAPPPAVKT", "length": 924 }, "evidence": [ { "id": "F1P2A7", "url": "https://omabrowser.org/oma/group/F1P2A7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1RXP8-1", "protein_name": "Exocyst complex component 2", "gene_name": "EXOC2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSRSRPPPLVTGISPNEGIPWTKVTIRGENLGTGTPDLIGLTICGHNCLLTAEWMSASKIVCRVGQAKNDKGDIIVTTKSGGRGTSTVSFKLLKPEKIGVLDQSAVWVDEMNYYDMRTDRNKGIPPLSLRPANPLGIEIEKGQFPQKDLEVLFPGMSADFTSENLSAAWYLIENHSNTSFEQLKMAVAHLKRQANKKSEGSLAYVKGGLSTFFEAQDALSAIHQKLEADGTEKVEGSMTQKLENVLNRASNTADTLFQEVLGRKDKADSTRNALTVLQRFKFLFNLPLNIERNIQKGDYDVVINDYEKAKSLFGKTEVQVFKKYYAEVETRIEALRELLLDKLLETPSTLHDQKRYIRYLSDLRAPGDPAWQCIGAQHRWILQLMHDCREGCARDLTGTSGLHSAVSDPDSDARPPALGHLGHTASLKRGSGFQSGRGDAWRYKTPQRVAFVEKLTKLVLSQLPNFWKLWISYVNGSLFSETAEKSGHIERSKNVRQRQSDFKKMIQEVMHCLVKLIRGALLPPSAAEGGVRPGTGREVKAELSGQWLAHVIQTLRLTYESLTALEIPSDLLQTIQDLVLDLRGRCVAATLQHTAEEIKRLAEKEDWVVDSEGLTSLPCQFERRVVQSLQSLRGVLECRPGEASVFQQPKTQEEVCQLSINIMQIFICCLEQLSTKPDADVDTAHLSVDVASPDLFGSIHQELSLTPEQRLLIVLSNCCYLERHTFRNIAEHFEKHNFQGIEKITQVSMASLKDLDQRLFENYIELKADPIVGSLEPGIYAGYFDWKDCLPPTGVRNYLKEALVSIIAVHAEVFAVCKGLVPRVLSRVVEAVSEELSRLMQCVSSFSRNGALQARLEICALRDILAAHLTPESRSSFKQALEALPQLSSGAERTSSHQCSLKAEKRRTRGTGNRPAVAWGGGRAKAAGRTAEPGQRQHAPAAGLLPGCPTACCEDLGVPPCCACPRPQCSRRQASV", "length": 976 }, "evidence": [ { "id": "F1P2A7", "url": "https://omabrowser.org/oma/group/F1P2A7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "O54921-1", "protein_name": "Exocyst complex component 2", "gene_name": "Exoc2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSRSRQPPLVTGISPNEGIPWTKVTIRGENLGTGPTDLIGLTICGHNCLLTAEWMSASKIVCRVGQAKNDKGDIIVTTKSGGRGTSTVSFKLLKPEKIGILDQSAVWVDEMNYYDMRTDRNKGIPPLSLRPANPLGIEIEKCKLPQKNLEVLFHGMSADFTSENFSAAWYLIENHSNTSFEQLKMAVTNLKRQANKKSEGSLAYVKGGLSTFFEAQDALSAIHQKLEADGTEKVEGSMTQKLENVLNRASNTADTLFQEVLGRKDKADSTRNALNVLQRFKFLFNLPLNIKRNIQKGDYDVVINDYEKAKSLFGKTEVQVFKKYYAEVEAGIEDLRELLLKKLLETPSTLHDQKRYIRYLSDLHAPGDPAWQCIGAQHKWTLKLMQDCKEGHMKSLKGNPGPHSPMLDLDNDARPSVLGHLSQTASLKRGSSFQSGRDDTWRYKTPHRVAFVEKLTKLVLSQLPNFWKLWISYVNGSLFSETAEKSGQIERSKNVRQRQNDFKKMIQEVMHSLVKLIRGALLPFSLREGDGRQYGGWEVQAELSGQWLAHVIQTIRLTYESLTALEIPNDMLQIIQDLILDLRIHCIMVTLQHTAEEIKRLAEKEDWIVDNEGLTSLPCQFEQSIVHSLQSLKGVVDCKPGEASVFQQPKTQEEVCQLCISIMQVFIYCLEQLSTKPDADIDTTHLSVDVSSPDLFGSIHEDFGLTSEQRLLIVLSNCCYLERHTFLNIAEHFEKHNFQGIEKITQVSMASLKELDQRLFENYIELKADPIVGSLETGIYAGYFDWKDCLPPAGVRNYLKEALVNIIAVHAEVFTISKELVPRVLARVIEAVSEELSRLMQCVSSFSRNGALQARLEICALRDTVAIYLTPESRSSFKQALEALPQLASGADKKLLEELLNKFKSSMHLQLTCFQAASPTVMKT", "length": 924 }, "evidence": [ { "id": "F1P2A7", "url": "https://omabrowser.org/oma/group/F1P2A7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P89102-1", "protein_name": "Exocyst complex component SEC5", "gene_name": "SEC5", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MDRFQIGDEQLLRFYQLKTINPTHSWAQDSSKLNNEEATSNELGVETSFDILKDFKYGNQISIDKESRAYLNDESLSYIRDPLNGQEMSKELQHLPNDSMRLNYLVNSKQFNVKAFLRDMHKQDSFNDLNNSLDRLDSDIQDQSIHLKQLVGKNFTKYVKIKNKLDQIYKEFDEKTNEKNQCDSPKENQINVESLNKKVDEVIRTTTFKLKPLMDNYQKILNYQATKKFIELNKFYFNLPKSLKRCLTNNDFNEFIIEYSKGLTLRRRFNQSSDASQSLVIKRIWTQIENLLVTYKDLIWNSLINSNFNIDQPQETILSLFSKLLNLENFINNNQRESESGNKNTTSSSNENPILRWMSIKMNGFQNELNELSGHMISKIIHSQRLILQNNTNQDKSQGCVELSYYLKINQLFQIISDTGKDSEGLKSTVEPNKVNTISGTSYLNLNCQPSSQGLTDSPTIIEMWLLILKYINDLWKICDQFIEFWEHIEKFLDGTYQNSIINEKRKENILIGDSNIIESYQKSLILKEEQINEVRLKGEEFITSVSQNLISFFTSSQSSLPSSLKDSTGDITRSNKDSGSPLDYGFIPPNCNGLSCLRYLPKIVEPILKFSTELAQLNITTNGITICRNTLSTIINRCVGAISSTKLRDISNFYQLENWQVYETVTFSSKSQDSSKNLTFEYGVTQFPEIVTSFQEVSIKTTRDLLFAYEKLPIINGISVVSYPSKQLLTGIEIQQIISMEAVLEAILKNAAKDKDNPRNSHTILTLTNLQYFRECAFPNILQYFDDAFEWNLASKNLELFSLLSKMESSIFGNYLSDLKINLRDTLEEKFHEINWPMYTSNSFRVGDYIIEALMILIVVHSECFRIGPQLIHKILIETQIFIARYLFEAFKPYVGNLSNDGSLQIIVDLEFFQKVMGPLLEKDTEATLRACLQNCFQNDTNRLQKCINEINPIVSANLKRTAIQFAAFS", "length": 971 }, "evidence": [ { "id": "F1P2A7", "url": "https://omabrowser.org/oma/group/F1P2A7/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q8S3U9-1", "protein_name": "Exocyst complex component SEC5A", "gene_name": "SEC5A", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSSDSNDLDEDELLQMALKEQAKRDLTYQKPPSSSARKPVANLVQQPRQQKPVAAAAAPPKKSAAAVRKPSMDEDEESEVELLSISSGDDDLEREREIGGSSGGAGRGRGSDVREKGRARKEDDGAWDGGEPDCWKRVNEAELARRVRDMRESRTAPVVQKVEGKAPAPGKKVALTSLQSLPRGMECIDPLKLGIIDNKTLRLITESSGSPSKAEKVDNTLREKLVYFSDHFDPKLFLSRIHQDTTAADLEAGALGLKSDLKGRNLQRKQLVKDNFDCFVSCKTTIDDIESKLKRIEEDPEGSGTTHLFNCMKSVTSRANLAFEPLFERQAQAEKIRSVQGMLQRFRTLFNLPSIIRSSISKGEYDLAVREYKKAKSIALPSHVNILKRVLEEVEKVMLEFKGTLYKSMEDPKIDFTSLENTVRLLLELEPESDPVWHYLNVQNHRIHGLLEKCTYDHEARVEILRNDTHEKAISDAKWQQIQQNGVSYSDTASSNENNAVQVDLQSVEFPSEEIDILKGRYIKRLTAVLVHHIPVFWKTAISIFSGKFAKSSQVTDTSANKAEEKVTEARYSTHSLEEVAGMIRKTISVYEAKVNSTFCDFDESCILRPFMSDAINEVSKACQAFEAKESTPHSAVVALRKIQAEITKIYIQRLCSWMRASTEGISKEETWIPVSILERNRSPYAISYLPLAFRSVIVSGMEQVNLMILSVKSEAAKSEDMFAQIEEIIISVRLAFLNCFLDFAAHLEQIGADLSQSTSRQDNWKNGYSDEHQEEPSANTYGSVIDPHRRLLMVLSNIGYCKDELASELYNKFKYTWLQSRDKNEDSSDLQDLIMSFSGLGEKVLEHYTFAKANLIRTAATNYLLDSGIQWGSAPQVKGIRDAAVELLHTLVAVHAEVFAGAKPLLDKILGVLIEGLIDTFLSVVEENRSSDLRSIDANGFCQLMFELEYFETVLYSYFTSAATESLKSLQGTVLEIAIESISEAVETPGHNRRPTRGSEDTVSDDKQSVSADDLLALTKQCSNELLQQELERTRVNTACFAESAPLESTPPLPKATYSSFRGSMDSPSRNYRGSQSSGSPINARPRRR", "length": 1090 }, "evidence": [ { "id": "F1P2A7", "url": "https://omabrowser.org/oma/group/F1P2A7/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q96KP1-1", "protein_name": "Exocyst complex component 2", "gene_name": "EXOC2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSRSRQPPLVTGISPNEGIPWTKVTIRGENLGTGPTDLIGLTICGHNCLLTAEWMSASKIVCRVGQAKNDKGDIIVTTKSGGRGTSTVSFKLLKPEKIGILDQSAVWVDEMNYYDMRTDRNKGIPPLSLRPANPLGIEIEKSKFSQKDLEMLFHGMSADFTSENFSAAWYLIENHSNTSFEQLKMAVTNLKRQANKKSEGSLAYVKGGLSTFFEAQDALSAIHQKLEADGTEKVEGSMTQKLENVLNRASNTADTLFQEVLGRKDKADSTRNALNVLQRFKFLFNLPLNIERNIQKGDYDVVINDYEKAKSLFGKTEVQVFKKYYAEVETRIEALRELLLDKLLETPSTLHDQKRYIRYLSDLHASGDPAWQCIGAQHKWILQLMHSCKEGYVKDLKGNPGLHSPMLDLDNDTRPSVLGHLSQTASLKRGSSFQSGRDDTWRYKTPHRVAFVEKLTKLVLSQLPNFWKLWISYVNGSLFSETAEKSGQIERSKNVRQRQNDFKKMIQEVMHSLVKLTRGALLPLSIRDGEAKQYGGWEVKCELSGQWLAHAIQTVRLTHESLTALEIPNDLLQTIQDLILDLRVRCVMATLQHTAEEIKRLAEKEDWIVDNEGLTSLPCQFEQCIVCSLQSLKGVLECKPGEASVFQQPKTQEEVCQLSINIMQVFIYCLEQLSTKPDADIDTTHLSVDVSSPDLFGSIHEDFSLTSEQRLLIVLSNCCYLERHTFLNIAEHFEKHNFQGIEKITQVSMASLKELDQRLFENYIELKADPIVGSLEPGIYAGYFDWKDCLPPTGVRNYLKEALVNIIAVHAEVFTISKELVPRVLSKVIEAVSEELSRLMQCVSSFSKNGALQARLEICALRDTVAVYLTPESKSSFKQALEALPQLSSGADKKLLEELLNKFKSSMHLQLTCFQAASSTMMKT", "length": 924 }, "evidence": [ { "id": "F1P2A7", "url": "https://omabrowser.org/oma/group/F1P2A7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9D4H1-1", "protein_name": "Exocyst complex component 2", "gene_name": "Exoc2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSRSRQPPLVTGISPNEGIPWTKVTIRGENLGTGPTDLIGLTICGHNCLLTAEWMSASKIVCRVGQAKNDKGDIIVTTKSGGKGTSTVSFKLLKPEKIGILDQSAVWVDEMNYYDMRTDRNKGIPPLSLRPANPLGIEIEKCKLPQKNLEVLFHGMSADFTSENFSAAWYLIENHSTTSFEQLKMAVTNLKRQANKKSEGSLAYVKGGLSTFFEAQDALSAIHQKLEADGTEKVEGSMTQKLENVLNRASNTADTLFQEVLGRKDKADSTRNALNVLQRFKFLFNLPLNIKRNIQKGDYDVVINDYEKAKSLFGKTEVQVFKKYYAEVEAGIEDLRELLLKKLLETPSTLHDQKRYIRYLSDLHAPGDPAWQCIGAQHKWTLKLMQDCKEGHMKSLKGHPGPHSPMLDLDNDVRPSVLGHLSQTASLKRGSSFQSGRDDTWRYKTPHRVAFVEKLTKLVLSQLPNFWKLWISYVNGSLFSETAEKSGQSERSKNVRQRQNDFKKMIQEVMHSLVKLIRGALLPLSLREGDGRQYGGWEVQAELSGQWLAHVIQTIRLTYESLTALEIPNDMLQIIQDLILDLRIRCIMVTLQHTAEEIKRLAEKEDWVVDNEGLTSLPCQFEQSIVHSLQSLKGVVDCKPGEASVFQQPKTQEEVCQLCINIMQVFIYCLEQLSTKPDADIDTTHLSVDVSSPDLFGSIHEDFSLTSEQRLLIVLSNCCYLERHTFLNIAEHFEKHNFQGIEKITQVSMASLKELDQRLFENYIELKADPIVGSLEPGIYAGYFDWKDCLPPAGVRNYLKEALVNIIAVHAEVFTISKELVPRVLARVVEAVSEELSRLMQCVSSFSRNGALQARLEICALRDTVAIYLTSESRSSFKQALEALPQLASGADKKSLEELLNKFKSSMHLQLTCFQAASPAVMKT", "length": 924 }, "evidence": [ { "id": "F1P2A7", "url": "https://omabrowser.org/oma/group/F1P2A7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VQQ9-1", "protein_name": "Exocyst complex component 2", "gene_name": "Sec5", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MAPQPVVTGLSPKEGPPGTRVIIRGEFLGTRVQDLIGLKICGSDCLLSAEWKSPNKIIARTGPAKGKGDIIVTTLSGGVGTSTVQFRAYHETIGPLKESAVWIEESPSQNFAWGRRTLAQSGLTQEDPLGLSIEGNEQKIPEDLRDLFPEACGDLSQEHFSPAWFLLENHLATSFEDLKAGLSYLKRKVESQKEGQLSFLKSNAGSVIDQLDTLMNIRDKLQEDVKLHGNETLNILETSIENSISESQKIFTDVLVRKEKADSTRSVLFALSRHKFLFCLPNSVDRRAKAGEYDIVVNDYSRAKNLFGKTEIPIFRKVLEEVDHRILSIRKQLHEKVVKMPQSVEQQKKLIKALISLELQQSGTPIGDKLRNIDPAWDAIEARAKYLEWTFRQTFDQHTSKDSGAQEKAKNRDSSQAPNRVNFCEELCDIAASQLPDLWRLGQLYFTGELRGPHDPKPGDFKRMVLNAIEKFCVYLRLAILIATDQRALRQSSGLAWPIGSASATHQFLPWIPQCLRFTRIAYATLISLDLPSEALDIIQKLIDEVRLFCFSIIFKRATDRCKKLGSQETWELGVEEYPGATLLPAALETLLIETLDEVQSVCMQRETREGNLLEPQSDGQREVTQRLQEFLSAFSAVIEELAFHSHDEETPTHNVSQLLGFPNAQQPDSVAGSGGAAAVTWEQRMLCCLANYAYCNKIFFPRLGDIFVRYGYPLPTLAIETARYTVNQLFTNLLEEYVEHKGDPLVGTIEPSMYLGRFQWDHEMEIGQLRPYAHECCDNLVGVYSEIYSISPALLRPILESIVQTISEELARLMSCVQRFSFTGAIQAHVDIRLLRDSLEGYVNETAKNYFMEALEAINPPLSGEQKRKADEILERVKRNMRLQLLCFSVKDP", "length": 894 }, "evidence": [ { "id": "F1P2A7", "url": "https://omabrowser.org/oma/group/F1P2A7/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "regulation of entry of bacterium into host cell", "id": "GO:2000535", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000535", "evidence": [ { "database": "UniProtKB", "id": "F1P2A7", "url": "https://www.uniprot.org/uniprotkb/F1P2A7" } ], "pmid": "" }, { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "F1P2A7", "url": "https://www.uniprot.org/uniprotkb/F1P2A7" } ], "pmid": "" }, { "name": "exocytosis", "id": "GO:0006887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006887", "evidence": [ { "database": "UniProtKB", "id": "F1P2A7", "url": "https://www.uniprot.org/uniprotkb/F1P2A7" } ], "pmid": "" }, { "name": "Golgi to plasma membrane transport", "id": "GO:0006893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006893", "evidence": [ { "database": "UniProtKB", "id": "F1P2A7", "url": "https://www.uniprot.org/uniprotkb/F1P2A7" } ], "pmid": "" }, { "name": "vesicle docking involved in exocytosis", "id": "GO:0006904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006904", "evidence": [ { "database": "UniProtKB", "id": "F1P2A7", "url": "https://www.uniprot.org/uniprotkb/F1P2A7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "protein kinase binding", "id": "GO:0019901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019901", "evidence": [ { "database": "UniProtKB", "id": "F1P2A7", "url": "https://www.uniprot.org/uniprotkb/F1P2A7" } ], "pmid": "" }, { "name": "small GTPase binding", "id": "GO:0031267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031267", "evidence": [ { "database": "UniProtKB", "id": "F1P2A7", "url": "https://www.uniprot.org/uniprotkb/F1P2A7" } ], "pmid": "" }, { "name": "GTP-dependent protein binding", "id": "GO:0030742", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030742", "evidence": [ { "database": "UniProtKB", "id": "F1P2A7", "url": "https://www.uniprot.org/uniprotkb/F1P2A7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "exocyst", "id": "GO:0000145", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000145", "evidence": [ { "database": "UniProtKB", "id": "F1P2A7", "url": "https://www.uniprot.org/uniprotkb/F1P2A7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 164, "end_pos": 166, "annotation": "n_glycosylation_sequon" }, { "start_pos": 174, "end_pos": 176, "annotation": "n_glycosylation_sequon" }, { "start_pos": 475, "end_pos": 477, "annotation": "n_glycosylation_sequon" }, { "start_pos": 875, "end_pos": 877, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1P2A7-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 925, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1P2A7-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1P2A7" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1P2A7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P2A7" }, { "id": "PF15469", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15469" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Exocyst complex component EXOC2/Sec5 N-terminal", "eco_id": "ECO_0000259", "start_pos": 133, "end_pos": 915, "start_aa": "Asn", "end_aa": "Phe", "glycosite_overlap": "" }, { "evidence": [ { "id": "F1P2A7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P2A7" }, { "id": "PF01833", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01833" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "IPT/TIG", "eco_id": "ECO_0000259", "start_pos": 8, "end_pos": 91, "start_aa": "Pro", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 164, "end_pos": 166 }, { "start_pos": 174, "end_pos": 176 }, { "start_pos": 475, "end_pos": 477 }, { "start_pos": 875, "end_pos": 877 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YCR5-1", "uniprot_ac": "A0A8V0YCR5", "uniprot_id": "A0A8V0YCR5_CHICK", "mass": { "chemical_mass": 56941.0, "monoisotopic_mass": 56941.0 }, "refseq": { "ac": "NP_001316429", "name": "cytochrome P450 2AC2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001316429" }, "gene_names": [ { "name": "CYP2AC2", "type": "recommended", "evidence": [ { "id": "A0A8V0YCR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCR5" } ] }, { "name": "CYP2AC2", "type": "synonym", "evidence": [ { "id": "NP_001316429", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001316429" } ] } ], "protein_names": [ { "name": "Cytochrome P450, family 2, subfamily AC, polypeptide 2", "type": "synonym", "evidence": [ { "id": "A0A8V0YCR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCR5/entry#names_and_taxonomy" } ] }, { "name": "cytochrome P450 2AC2", "type": "synonym", "evidence": [ { "id": "NP_001316429", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001316429" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: SRR13267659.276232.1, SRR12888529.101594.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992323, SAMEA103992428 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000070.1. On Sep 23, 2021 this sequence version replaced NP_001316429.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001316429", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001316429" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCR5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCR5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CYP2AC2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCR5", "locus": { "chromosome": "3", "start_pos": 108591891, "end_pos": 108582708, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010011879", "url": "https://www.ensembl.org/id/ENSGALG00010011879" } ] } } ], "crossref": [ { "id": "A0A8V0YCR5", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YCR5", "database": "AlphaFoldDB", "categories": [] }, { "id": "107049058", "url": "https://www.ncbi.nlm.nih.gov/gene/107049058", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001128", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001128", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002401", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002401", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017972", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017972", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036396", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036396", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050182", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050182", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:107049058", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:107049058", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WLDGHET", "url": "https://omabrowser.org/oma/group/WLDGHET/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y6I7", "url": "https://www.orthodb.org/?gene=A0A8V0Y6I7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YCR5", "url": "https://www.orthodb.org/?gene=A0A8V0YCR5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24300", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24300", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24300:SF302", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24300:SF302", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00067", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00067", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001316429", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001316429", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Y6I7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y6I7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y6I7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y6I7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YCR5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCR5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YCR5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCR5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDWSNCTTMALVFILTFLFIMKIGGLWSNHWRKNFPPGPRALPIIGNLHLFDLKRPYRTYLQLSKEYGPVFSVQMGQRKIVVISGYETVKEALINQADAFAERPKIPIFEDLTRGNGIVFAHGENWKVMRRFTLTTLRDFGMGKRAIEDRIVEEYGYLIDNVGSQEGKPFDASKIINAAVANIIVSILLGKRFDYKDSRFIRLQHLTNESMRLAGKPLVTMYNIFPYLGFLLRANKTLLKNRDEFHAYVKATFLENLKTLDKNDQRSFIDAFLVKQQEEKSTTNGYFHNGNLLSLVSNLFTAGVETISTTLNWSFLLMLKYPEIQRKVQEEIEQVIGSNPPRIEHRTQMPYTDAVIHEVQRFANILPLDLPHETAEDVTLKDYFIPKGTYIIPLLTSVLRDKSQWEKPDVFYPEHFLDSKGKFVKKDAFMPFSAGRRICAGETLAKMELFLFFTSLLQRFTFQPPPGVSSSDLDLSPAISFNVVPKPYKICAVARS", "length": 496, "header": "tr|A0A8V0YCR5-1|A0A8V0YCR5_CHICK Isoform 1 of Cytochrome P450, family 2, subfamily AC, polypeptide 2 OS=Gallus gallus OX=9031 GN=CYP2AC2 PE=1 SV=1 CANONICAL=A0A8V0YCR5-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Y6I7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCR5/entry#A0A8V0Y6I7-1", "sequence": { "sequence": "MKLKRCQLWQNCLGKHFPNLWTRQLSKEYGPVFSVQMGQRKIVVISGYETVKEALINQADAFAERPKIPIFEDLTRGNGIVFAHGENWKVMRRFTLTTLRDFGMGKRAIEDRIVEEYGYLIDNVGSQEGKPFDASKIINAAVANIIVSILLGKRFDYKDSRFIRLQHLTNESMRLAGKPLVTMYNIFPYLGFLLRANKTLLKNRDEFHAYVKATFLENLKTLDKNDQRSFIDAFLVKQQEEKSTTNGYFHNGNLLSLVSNLFTAGVETISTTLNWSFLLMLKYPEIQRKVQEEIEQVIGSNPPRIEHRTQMPYTDAVIHEVQRFANILPLDLPHETAEDVTLKDYFIPKGTYIIPLLTSVLRDKSQWEKPDVFYPEHFLDSKGKFVKKDAFMPFSAGRRICAGETLAKMELFLFFTSLLQRFTFQPPPGVSSSDLDLSPAISFNVVPKPYKICAVARS", "length": 458, "header": "tr|A0A8V0Y6I7-1|A0A8V0Y6I7_CHICK Computationally mapped isoform of Cytochrome P450, family 2, subfamily AC, polypeptide 2 OS=Gallus gallus OX=9031 GN=CYP2AC2 PE=1 SV=1 CANONICAL=A0A8V0YCR5-1" }, "locus": { "chromosome": "3", "start_pos": 108590508, "end_pos": 108584178, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028385.1", "url": "https://www.ensembl.org/id/ENSGALT00010028385.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016270.1", "url": "https://www.ensembl.org/id/ENSGALP00010016270.1" } ] } }, { "isoform_ac": "A0A8V0YCR5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCR5/entry#A0A8V0YCR5-1", "sequence": { "sequence": "MDWSNCTTMALVFILTFLFIMKIGGLWSNHWRKNFPPGPRALPIIGNLHLFDLKRPYRTYLQLSKEYGPVFSVQMGQRKIVVISGYETVKEALINQADAFAERPKIPIFEDLTRGNGIVFAHGENWKVMRRFTLTTLRDFGMGKRAIEDRIVEEYGYLIDNVGSQEGKPFDASKIINAAVANIIVSILLGKRFDYKDSRFIRLQHLTNESMRLAGKPLVTMYNIFPYLGFLLRANKTLLKNRDEFHAYVKATFLENLKTLDKNDQRSFIDAFLVKQQEEKSTTNGYFHNGNLLSLVSNLFTAGVETISTTLNWSFLLMLKYPEIQRKVQEEIEQVIGSNPPRIEHRTQMPYTDAVIHEVQRFANILPLDLPHETAEDVTLKDYFIPKGTYIIPLLTSVLRDKSQWEKPDVFYPEHFLDSKGKFVKKDAFMPFSAGRRICAGETLAKMELFLFFTSLLQRFTFQPPPGVSSSDLDLSPAISFNVVPKPYKICAVARS", "length": 496, "header": "tr|A0A8V0YCR5-1|A0A8V0YCR5_CHICK Isoform 1 of Cytochrome P450, family 2, subfamily AC, polypeptide 2 OS=Gallus gallus OX=9031 GN=CYP2AC2 PE=1 SV=1 CANONICAL=A0A8V0YCR5-1" }, "locus": { "chromosome": "3", "start_pos": 108590508, "end_pos": 108582729, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028389.1", "url": "https://www.ensembl.org/id/ENSGALT00010028389.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016272.1", "url": "https://www.ensembl.org/id/ENSGALP00010016272.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:107049058", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:107049058", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "Q9ZUQ6-1", "protein_name": "Cytochrome P450 superfamily protein", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MEIWLLILGSLFLSLLLNLLLFRRRDSSSLPLPPDPNFFPFLGTLQWLRQGLGGLNNYLRSVHHRLGPIITLRITSRPAIFVADRSLAHQALVLNGAVFADRPPAAPISKIISSNQHNISSSLYGATWRLLRRNLTSEILHPSRVRSYSHARRWVLEILFDRFGKSRGEEPIVVVDHLHYAMFALLVLMCFGDKLDEKQIKQVEYVQRRQLLGFSRFNILNLWPKFTKLILRKRWEEFFQMRREQHDVLLPLIRARRKIVEERKNRSSEEEEDNKVYVQSYVDTLLELELPDEKRKLNEDEIVSLCSEFLNGGTDTTATALQWIMANLVKNPEIQKRLYEEIKSVVGEEAKEVEEEDAQKMPYLKAVVMEGLRRHPPGHFVLPHSVTEDTVLGGYKVPKKGTINFMVAEIGRDPMVWEEPMAFKPERFMGEEEAVDITGSRGIKMMPFGAGRRICPGIGLAMLHLEYYVANMVREFEWKEVQGHEVDLTEKFEFTVVMKHSLKALAVLRRSH", "length": 512 }, "evidence": [ { "id": "A0A8V0YCR5", "url": "https://omabrowser.org/oma/group/A0A8V0YCR5/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "iron ion binding", "id": "GO:0005506", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005506", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCR5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCR5" } ], "pmid": "" }, { "name": "heme binding", "id": "GO:0020037", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0020037", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCR5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCR5" } ], "pmid": "" }, { "name": "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen", "id": "GO:0016712", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016712", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCR5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCR5" } ], "pmid": "" }, { "name": "monooxygenase activity", "id": "GO:0004497", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004497", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCR5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCR5" } ], "pmid": "" }, { "name": "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen", "id": "GO:0016705", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016705", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCR5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCR5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCR5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCR5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "xenobiotic metabolic process", "id": "GO:0006805", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006805", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCR5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCR5" } ], "pmid": "" }, { "name": "organic acid metabolic process", "id": "GO:0006082", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006082", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCR5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCR5" } ], "pmid": "" }, { "name": "aflatoxin metabolic process", "id": "GO:0046222", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046222", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCR5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCR5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 208, "end_pos": 210, "annotation": "n_glycosylation_sequon" }, { "start_pos": 235, "end_pos": 237, "annotation": "n_glycosylation_sequon" }, { "start_pos": 312, "end_pos": 314, "annotation": "n_glycosylation_sequon" }, { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 208, "end_pos": 210 }, { "start_pos": 235, "end_pos": 237 }, { "start_pos": 312, "end_pos": 314 }, { "start_pos": 5, "end_pos": 7 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YCS6-1", "uniprot_ac": "A0A8V0YCS6", "uniprot_id": "A0A8V0YCS6_CHICK", "mass": { "chemical_mass": 41217.0, "monoisotopic_mass": 41217.0 }, "refseq": {}, "gene_names": [ { "name": "TMEM171", "type": "recommended", "evidence": [ { "id": "A0A8V0YCS6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCS6" } ] } ], "protein_names": [ { "name": "Transmembrane protein 171", "type": "synonym", "evidence": [ { "id": "A0A8V0YCS6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCS6/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCS6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCS6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TMEM171", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCS6", "locus": { "chromosome": "Z", "start_pos": 25454368, "end_pos": 25471484, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012087", "url": "https://www.ensembl.org/id/ENSGALG00010012087" } ] } } ], "crossref": [ { "id": "A0A8V0YCS6", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YCS6", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR029173", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029173", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YCR7", "url": "https://www.orthodb.org/?gene=A0A8V0YCR7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YCS1", "url": "https://www.orthodb.org/?gene=A0A8V0YCS1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YCS6", "url": "https://www.orthodb.org/?gene=A0A8V0YCS6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YKY1", "url": "https://www.orthodb.org/?gene=A0A8V0YKY1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YKY4", "url": "https://www.orthodb.org/?gene=A0A8V0YKY4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31617", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31617", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31617:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31617:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15471", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15471", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YCR7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCR7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YCR7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCR7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YCS1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCS1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YCS1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCS1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YCS6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCS6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YCS6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCS6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YKY1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKY1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YKY1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKY1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YKY4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKY4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YKY4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKY4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MYSVTVPVPVGEANNGQHKKATFFLFLFGAILLCGGFLLSVFTLQSCPFETFSDCSGVLKASGPVLGVTGLLCILIARSRARLYISQRQLQNEQICSLFFCRGNCQFAQFLIFGFLFLTSGMLISILGIWVPGCSPGWPNIQLNQTSSSDGDLQGCGFLSFQILGPLIVLTGLCFFVIAHVKKKQNLNLNEESLENEERPQSPESFQVTLGDAVLMFPPPPPPYFADPLSPAVTHCLMSSGLPASRNPPPYHSVFSDREQFADDERTVAARDDETIYTISGCSSPLGISPVRFFSSEPPPDYEEKASVESFGEQSCSELVLEHSRLKALLLVAEKQSKRRQGEEAFVGAKLKKRINKKISSHARVKPFRKQWW", "length": 373, "header": "tr|A0A8V0YCS6-1|A0A8V0YCS6_CHICK Isoform 1 of Transmembrane protein 171 OS=Gallus gallus OX=9031 GN=TMEM171 PE=4 SV=1 CANONICAL=A0A8V0YCS6-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YCR7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCS6/entry#A0A8V0YCR7-1", "sequence": { "sequence": "MYSVTVPVPVGEANNGQHKKATFFLFLFGAILLCGGFLLSVFTLQSCPFETFSDCSGVLKASGPVLGVTGLLCILIARSRARLYISQRQLQNEQICSLFFCRGNCQFAQFLIFGFLFLTSGMLISILGIWVPGCSPGWPNIQLNQTSSSDGDLQGCGFLSFQILGPLIVLTGLCFFVIAHVKKKQNLNLNEESLENEERPQSPESFQVTLGDAVLMFPPPPPPYFADPLSPAVTHCLMSSGLPASRNPPPYHSVFSDREQFADDERTVAARDDETIYTISGCSSPLGISPVRFFSSEPPPDYEEKASVEKSPLWFTSFLKTRLQGKLLAWLLGVS", "length": 335, "header": "tr|A0A8V0YCR7-1|A0A8V0YCS6_CHICK Computationally mapped isoform of Transmembrane protein 171 OS=Gallus gallus OX=9031 GN=TMEM171 PE=4 SV=1 CANONICAL=A0A8V0YCS6-1" }, "locus": { "chromosome": "Z", "start_pos": 25466505, "end_pos": 25458252, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028962.1", "url": "https://www.ensembl.org/id/ENSGALT00010028962.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016721.1", "url": "https://www.ensembl.org/id/ENSGALP00010016721.1" } ] } }, { "isoform_ac": "A0A8V0YCS1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCS6/entry#A0A8V0YCS1-1", "sequence": { "sequence": "MYSVTVPVPVGEANNGQHKKATFFLFLFGAILLCGGFLLSVFTLQSCPFETFSDCSGVLKASGPVLGVTGLLCILIARSRARLYISQRQLQNEQICSLFFCRGNCQFAQFLIFGFLFLTSGMLISILGIWVPGCSPGWPNIQLNQTSSSDGDLQGCGFLSFQILGPLIVLTGLCFFVIAHVKKKQNLNLNEESLENEERPQSPESFQVTLGDAVLMFPPPPPPYFADPLSPAVTHCLMSSGLPASRNPPPYHSVFSDREQFADDERTVAARDDETIYTISGCSSPLGISPVRFFSSEPPPDYEEKASVESRVRKHSWAPN", "length": 320, "header": "tr|A0A8V0YCS1-1|A0A8V0YCS1_CHICK Computationally mapped isoform of Transmembrane protein 171 OS=Gallus gallus OX=9031 GN=TMEM171 PE=4 SV=1 CANONICAL=A0A8V0YCS6-1" }, "locus": { "chromosome": "Z", "start_pos": 25466505, "end_pos": 25454940, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028967.1", "url": "https://www.ensembl.org/id/ENSGALT00010028967.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016726.1", "url": "https://www.ensembl.org/id/ENSGALP00010016726.1" } ] } }, { "isoform_ac": "A0A8V0YCS6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCS6/entry#A0A8V0YCS6-1", "sequence": { "sequence": "MYSVTVPVPVGEANNGQHKKATFFLFLFGAILLCGGFLLSVFTLQSCPFETFSDCSGVLKASGPVLGVTGLLCILIARSRARLYISQRQLQNEQICSLFFCRGNCQFAQFLIFGFLFLTSGMLISILGIWVPGCSPGWPNIQLNQTSSSDGDLQGCGFLSFQILGPLIVLTGLCFFVIAHVKKKQNLNLNEESLENEERPQSPESFQVTLGDAVLMFPPPPPPYFADPLSPAVTHCLMSSGLPASRNPPPYHSVFSDREQFADDERTVAARDDETIYTISGCSSPLGISPVRFFSSEPPPDYEEKASVESFGEQSCSELVLEHSRLKALLLVAEKQSKRRQGEEAFVGAKLKKRINKKISSHARVKPFRKQWW", "length": 373, "header": "tr|A0A8V0YCS6-1|A0A8V0YCS6_CHICK Isoform 1 of Transmembrane protein 171 OS=Gallus gallus OX=9031 GN=TMEM171 PE=4 SV=1 CANONICAL=A0A8V0YCS6-1" }, "locus": { "chromosome": "Z", "start_pos": 25466505, "end_pos": 25454872, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028972.1", "url": "https://www.ensembl.org/id/ENSGALT00010028972.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016731.1", "url": "https://www.ensembl.org/id/ENSGALP00010016731.1" } ] } }, { "isoform_ac": "A0A8V0YKY1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCS6/entry#A0A8V0YKY1-1", "sequence": { "sequence": "MYSVTVPVPVGEANNGQHKKATFFLFLFGAILLCGGFLLSVFTLQSCPFETFSDCSGVLKASGPVLGVTGLLCILIARSRARLYISQRQLQNEQICSLFFCRGNCQFAQFLIFGFLFLTSGMLISILGIWVPGCSPGWPNIQLNQTSSSDGDLQGCGFLSFQILGPLIVLTGLCFFVIAHVKKKQNLNLNEESLENEERPQSPESFQVTLGDAVLMFPPPPPPYFADPLSPAVTHCLMSSGLPASRNPPPYHSVFSDREQFADDERTVAARDDETIYTISGCSSPLGISPVRFFSSEPPPDYEEKASVEKIQLSFGSSKPVWLHKSAVAACLHRGLARSCRSTLNVCSCSQVESCACRS", "length": 359, "header": "tr|A0A8V0YKY1-1|A0A8V0YKY1_CHICK Computationally mapped isoform of Transmembrane protein 171 OS=Gallus gallus OX=9031 GN=TMEM171 PE=4 SV=1 CANONICAL=A0A8V0YCS6-1" }, "locus": { "chromosome": "Z", "start_pos": 25466505, "end_pos": 25459669, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028959.1", "url": "https://www.ensembl.org/id/ENSGALT00010028959.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016718.1", "url": "https://www.ensembl.org/id/ENSGALP00010016718.1" } ] } }, { "isoform_ac": "A0A8V0YKY4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCS6/entry#A0A8V0YKY4-1", "sequence": { "sequence": "MYSVTVPVPVGEANNGQHKKATFFLFLFGAILLCGGFLLSVFTLQSCPFETFSDCSGVLKASGPVLGVTGLLCILIARSRARLYISQRQLQNEQICSLFFCRGNCQFAQFLIFGFLFLTSGMLISILGIWVPGCSPGWPNIQLNQTSSSDGDLQGCGFLSFQILGPLIVLTGLCFFVIAHVKKKQNLNLNEESLENEERPQSPESFQVTLGDAVLMFPPPPPPYFADPLSPAVTHCLMSSGLPASRNPPPYHSVFSDREQFADDERTVAARDDETIYTISGCSSPLGISPVRFFSSEPPPDYEEKASVESFGEQSCSELVLEHSRLKALLLVAEKQSKRR", "length": 340, "header": "tr|A0A8V0YKY4-1|A0A8V0YKY4_CHICK Computationally mapped isoform of Transmembrane protein 171 OS=Gallus gallus OX=9031 GN=TMEM171 PE=4 SV=1 CANONICAL=A0A8V0YCS6-1" }, "locus": { "chromosome": "Z", "start_pos": 25466505, "end_pos": 25456169, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028964.1", "url": "https://www.ensembl.org/id/ENSGALT00010028964.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016723.1", "url": "https://www.ensembl.org/id/ENSGALP00010016723.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 144, "end_pos": 146, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 144, "end_pos": 146 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YCT7-1", "uniprot_ac": "A0A8V0YCT7", "uniprot_id": "A0A8V0YCT7_CHICK", "mass": { "chemical_mass": 61932.0, "monoisotopic_mass": 61932.0 }, "refseq": {}, "gene_names": [ { "name": "FIP1L1L", "type": "recommended", "evidence": [ { "id": "A0A8V0YCT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCT7" } ] } ], "protein_names": [ { "name": "Pre-mRNA polyadenylation factor Fip1 domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A8V0YCT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCT7/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCT7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCT7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "FIP1L1L", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCT7", "locus": {} } ], "crossref": [ { "id": "A0A8V0YCT7", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YCT7", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR007854", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007854", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035352", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035352", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051187", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051187", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "QHSRAGF", "url": "https://omabrowser.org/oma/group/QHSRAGF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YCT7", "url": "https://www.orthodb.org/?gene=A0A8V0YCT7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YE23", "url": "https://www.orthodb.org/?gene=A0A8V0YE23", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13484", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13484", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13484:SF8", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13484:SF8", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05182", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05182", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17397", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17397", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YCT7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCT7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YCT7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCT7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YE23", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE23", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YE23-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE23-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MATELEPPAAGAVSGGAPLEAEEDEEHWLYGDDTTGKQEDGPTSGHAESSHPLQDAPQENRPVGSEDREVSQHALPSGEDDEEDSDSDSDDDDVKVTIGNIKTGAPSYMGTPMNLNLKTGRGYGASASAKLQPKGIDLDAAGNINGLPVIEVDLDSFEDKPWRKPGADLSDYFNYGFNEETWKAYCEKQRRLQLGLDPAPPISAENKITVQQGRTGNAEKEVENNIIKTEFKTDFLALVGGRMKAGPPPNRKLGGTIDVIGGQAGTIRRVEGRRRDKHASEENPIQVLGDHGSKPQPPQQPQQPAQPQQPPQQQPFAPPAGPPPPPLAGPPPPHFLHPPPPVTSVPPPLHPPGLPPPGPIPGLFPPPLAPPPALLIPTLDGQPASYNNRQPPPFGYNSADSGFISYPPISTSHTPWVTTVDKGASGSGSSHWEYSGSRRERERERDRERDRDRTPTTSEYNTEDERYRYYGRERSYDFERDYRRSRDRSREREDRHRERRHRDKEESSKHKSSRRKQHESEEGESHRRHKHKKNKRSKEEKETSEDGTQEGEEQDSKE", "length": 558, "header": "tr|A0A8V0YCT7-1|A0A8V0YCT7_CHICK Isoform 1 of Pre-mRNA polyadenylation factor Fip1 domain-containing protein OS=Gallus gallus OX=9031 GN=FIP1L1L PE=1 SV=1 CANONICAL=A0A8V0YCT7-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YCT7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCT7/entry#A0A8V0YCT7-1", "sequence": { "sequence": "MATELEPPAAGAVSGGAPLEAEEDEEHWLYGDDTTGKQEDGPTSGHAESSHPLQDAPQENRPVGSEDREVSQHALPSGEDDEEDSDSDSDDDDVKVTIGNIKTGAPSYMGTPMNLNLKTGRGYGASASAKLQPKGIDLDAAGNINGLPVIEVDLDSFEDKPWRKPGADLSDYFNYGFNEETWKAYCEKQRRLQLGLDPAPPISAENKITVQQGRTGNAEKEVENNIIKTEFKTDFLALVGGRMKAGPPPNRKLGGTIDVIGGQAGTIRRVEGRRRDKHASEENPIQVLGDHGSKPQPPQQPQQPAQPQQPPQQQPFAPPAGPPPPPLAGPPPPHFLHPPPPVTSVPPPLHPPGLPPPGPIPGLFPPPLAPPPALLIPTLDGQPASYNNRQPPPFGYNSADSGFISYPPISTSHTPWVTTVDKGASGSGSSHWEYSGSRRERERERDRERDRDRTPTTSEYNTEDERYRYYGRERSYDFERDYRRSRDRSREREDRHRERRHRDKEESSKHKSSRRKQHESEEGESHRRHKHKKNKRSKEEKETSEDGTQEGEEQDSKE", "length": 558, "header": "tr|A0A8V0YCT7-1|A0A8V0YCT7_CHICK Isoform 1 of Pre-mRNA polyadenylation factor Fip1 domain-containing protein OS=Gallus gallus OX=9031 GN=FIP1L1L PE=1 SV=1 CANONICAL=A0A8V0YCT7-1" }, "locus": { "chromosome": "4", "start_pos": 12125714, "end_pos": 12102904, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028987.1", "url": "https://www.ensembl.org/id/ENSGALT00010028987.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016746.1", "url": "https://www.ensembl.org/id/ENSGALP00010016746.1" } ] } }, { "isoform_ac": "A0A8V0YE23-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCT7/entry#A0A8V0YE23-1", "sequence": { "sequence": "MSQLDDTTGKQEDGPTSGHAESSHPLQDAPQENRPVGSEDREVSQHALPSGEDDEEDSDSDSDDDDVKVTIGNIKTGAPSYMGTPMNLNLKTGRGYGASASAKLQPKGIDLDAAGNINGLPVIEVDLDSFEDKPWRKPGADLSDYFNYGFNEETWKAYCEKQRRLQLGLDPAPPISAENKITVQQGRTGNAEKEVENNIIKTEFKTDFLALVGGRMKAGPPPNRKLGGTIDVIGGQAGTIRRVEGRRRDKHASEENPIQVLGDHGSKPQPPQQPQQPAQPQQPPQQQPFAPPAGPPPPPLAGPPPPHFLHPPPPVTSVPPPLHPPGLPPPGPIPGLFPPPLAPPPALLIPTLDGQPASYNNRQPPPFGYNSADSGFISYPPISTSHTPWVTTVDKGASGSGSSHWEYSGSRRERERERDRERDRDRTPTTSEYNTEDERYRYYGRERSYDFERDYRRSRDRSREREDRHRERRHRDKEESSKHKSSRRKQHESEEGESHRRHKHKKNKRSKEEKETSEDGTQEGEEQDSKE", "length": 531, "header": "tr|A0A8V0YE23-1|A0A8V0YE23_CHICK Computationally mapped isoform of Pre-mRNA polyadenylation factor Fip1 domain-containing protein OS=Gallus gallus OX=9031 GN=FIP1L1L PE=1 SV=1 CANONICAL=A0A8V0YCT7-1" }, "locus": { "chromosome": "4", "start_pos": 12125714, "end_pos": 12103465, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028985.1", "url": "https://www.ensembl.org/id/ENSGALT00010028985.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016744.1", "url": "https://www.ensembl.org/id/ENSGALP00010016744.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 43, "start_aa": "Thr", "end_pos": 43, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr43", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "mRNA cleavage and polyadenylation specificity factor complex", "id": "GO:0005847", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005847", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCT7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCT7" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCT7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCT7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "mRNA 3'-end processing by stem-loop binding and cleavage", "id": "GO:0006398", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006398", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCT7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCT7" } ], "pmid": "" }, { "name": "mRNA processing", "id": "GO:0006397", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006397", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCT7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCT7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YCT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCT7" }, { "id": "PF05182", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05182" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Pre-mRNA polyadenylation factor Fip1", "eco_id": "ECO_0000259", "start_pos": 151, "end_pos": 192, "start_aa": "Glu", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 43 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YCU9-1", "uniprot_ac": "A0A8V0YCU9", "uniprot_id": "A0A8V0YCU9_CHICK", "mass": { "chemical_mass": 118304.0, "monoisotopic_mass": 118304.0 }, "refseq": { "ac": "XP_015138335", "name": "leucine-rich repeat and coiled-coil domain-containing protein 1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015138335" }, "gene_names": [ { "name": "LRRCC1", "type": "recommended", "evidence": [ { "id": "A0A8V0YCU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCU9" } ] }, { "name": "LRRCC1", "type": "synonym", "evidence": [ { "id": "XP_015138335", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015138335" } ] } ], "protein_names": [ { "name": "Leucine-rich repeat and coiled-coil domain-containing protein 1", "type": "recommended", "evidence": [ { "id": "A0A8V0YCU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCU9/entry#names_and_taxonomy" } ] }, { "name": "leucine-rich repeat and coiled-coil domain-containing protein 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015138335", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015138335" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052533.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015138335.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015138335", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015138335" } ] }, { "annotation": "Required for the organization of the mitotic spindle. Maintains the structural integrity of centrosomes during mitosis.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCU9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCU9#function" }, { "database": "UniProtKB", "id": "ARBA00054059", "url": "https://www.uniprot.org/uniprotkb/ARBA00054059#function" }, { "database": "UniProtKB", "id": "A0A8V0YIF4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIF4#function" }, { "database": "UniProtKB", "id": "A0A8V0YL58", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL58#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCU9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCU9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LRRCC1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCU9", "locus": { "chromosome": "2", "start_pos": 122290452, "end_pos": 122270921, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013233", "url": "https://www.ensembl.org/id/ENSGALG00010013233" } ] } } ], "crossref": [ { "id": "A0A8V0YCU9", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YCU9", "database": "AlphaFoldDB", "categories": [] }, { "id": "420205", "url": "https://www.ncbi.nlm.nih.gov/gene/420205", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001611", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001611", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003591", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003591", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003603", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003603", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR025875", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025875", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "RDQQDDH", "url": "https://omabrowser.org/oma/group/RDQQDDH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YCU9", "url": "https://www.orthodb.org/?gene=A0A8V0YCU9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YIF4", "url": "https://www.orthodb.org/?gene=A0A8V0YIF4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YL58", "url": "https://www.orthodb.org/?gene=A0A8V0YL58", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15454", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15454", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15454:SF34", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15454:SF34", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF12799", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12799", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015138335", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015138335", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YCU9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCU9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YCU9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCU9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YIF4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIF4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YIF4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIF4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YL58", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL58", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YL58-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL58-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAGQGGEPEELSLVDKGVRSLLEVSLSSDLHTLNMHCNRIARIEGLGHLRNLQHLDLSSNQIRRMEGLNALESLRSLNLSCNLITAVEGLEKLFNLTTLNLSHNHIHDLSGFQYLHGTHHKISCIDLRSNCINNINHLLQCTKGLQCLTNLTLEKYGNTNPVCYAAGYRETVLQALPQLAVLDGRNIHGELVESAEGNSSNLQCLEDILNSLVSSGSPSSKDQKALPLVTPHIDQALAYFRQRTKIPVQSSVSSSTERVSSSEPEKSILDKIQSEMRIQKLEDQISQILQKVSDASRREAPPNVLKAKRDTDPTSESEHETEKESSKKAVKRSKIPTYHRTTLSARRHLNHPKTKITDREEKSSSKRSPSHQRNSHLNSSSDTPDLEVVGRRANVLTGRQSNVEKVDEMNSNATKESTYRVLIQELDQEKERRWKAEQAEKKLVEHVKELQKHAKEEKNIQSMAVYTTERLKEMILKERDVKTRLQADLQQLKDETERLTNELNQAKNKEAEHQKAMQALEEALSKMETQRLQQRAIEMKQVQEAELKASANERELQLLRVSLRQQREKVKQLHELLILREREQRKELETRVALHGPEFQAAVSKEVAKEEQRHEQRVKDFQEKINMLNQKYTELEDEFRLALTIEAKRFKEVQEDFENVSADLAEHQQALFQFQQKEKEMTVLIQDLTSIVKEQKAKIAELVKSNQETTANLKSRTEELETVIEQNKEKAGQVELLKKENGKLISQLTAQESVIDGLRMERKIWGQELAQQGAHLSQDRGKLEAKIEVLTNEVEILKKQREQDGDAIRIKNKIVDDQTETIRRLKEGLQEKDKQIRKQHEENKLFQVQLDEKATEFEELMEKLERQNERKEQLKQHLEEKEVELSDIRRAHSALKKKWQGKDELLSQLEVQVKQMKEGFDMKEKKLIEERNKSLQAQRIATEKLREMDDAFRKQLESVLAAHEAEIVQLANEKEKQVEAANEKVYYVEEEMRQLLQETANNKKAMEDKIRRITYVLSDIQQDL", "length": 1024, "header": "tr|A0A8V0YCU9-1|A0A8V0YCU9_CHICK Isoform 1 of Leucine-rich repeat and coiled-coil domain-containing protein 1 OS=Gallus gallus OX=9031 GN=LRRCC1 PE=3 SV=1 CANONICAL=A0A8V0YCU9-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YCU9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCU9/entry#A0A8V0YCU9-1", "sequence": { "sequence": "MAGQGGEPEELSLVDKGVRSLLEVSLSSDLHTLNMHCNRIARIEGLGHLRNLQHLDLSSNQIRRMEGLNALESLRSLNLSCNLITAVEGLEKLFNLTTLNLSHNHIHDLSGFQYLHGTHHKISCIDLRSNCINNINHLLQCTKGLQCLTNLTLEKYGNTNPVCYAAGYRETVLQALPQLAVLDGRNIHGELVESAEGNSSNLQCLEDILNSLVSSGSPSSKDQKALPLVTPHIDQALAYFRQRTKIPVQSSVSSSTERVSSSEPEKSILDKIQSEMRIQKLEDQISQILQKVSDASRREAPPNVLKAKRDTDPTSESEHETEKESSKKAVKRSKIPTYHRTTLSARRHLNHPKTKITDREEKSSSKRSPSHQRNSHLNSSSDTPDLEVVGRRANVLTGRQSNVEKVDEMNSNATKESTYRVLIQELDQEKERRWKAEQAEKKLVEHVKELQKHAKEEKNIQSMAVYTTERLKEMILKERDVKTRLQADLQQLKDETERLTNELNQAKNKEAEHQKAMQALEEALSKMETQRLQQRAIEMKQVQEAELKASANERELQLLRVSLRQQREKVKQLHELLILREREQRKELETRVALHGPEFQAAVSKEVAKEEQRHEQRVKDFQEKINMLNQKYTELEDEFRLALTIEAKRFKEVQEDFENVSADLAEHQQALFQFQQKEKEMTVLIQDLTSIVKEQKAKIAELVKSNQETTANLKSRTEELETVIEQNKEKAGQVELLKKENGKLISQLTAQESVIDGLRMERKIWGQELAQQGAHLSQDRGKLEAKIEVLTNEVEILKKQREQDGDAIRIKNKIVDDQTETIRRLKEGLQEKDKQIRKQHEENKLFQVQLDEKATEFEELMEKLERQNERKEQLKQHLEEKEVELSDIRRAHSALKKKWQGKDELLSQLEVQVKQMKEGFDMKEKKLIEERNKSLQAQRIATEKLREMDDAFRKQLESVLAAHEAEIVQLANEKEKQVEAANEKVYYVEEEMRQLLQETANNKKAMEDKIRRITYVLSDIQQDL", "length": 1024, "header": "tr|A0A8V0YCU9-1|A0A8V0YCU9_CHICK Isoform 1 of Leucine-rich repeat and coiled-coil domain-containing protein 1 OS=Gallus gallus OX=9031 GN=LRRCC1 PE=3 SV=1 CANONICAL=A0A8V0YCU9-1" }, "locus": { "chromosome": "2", "start_pos": 122290248, "end_pos": 122270985, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031806.1", "url": "https://www.ensembl.org/id/ENSGALT00010031806.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018622.1", "url": "https://www.ensembl.org/id/ENSGALP00010018622.1" } ] } }, { "isoform_ac": "A0A8V0YIF4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCU9/entry#A0A8V0YIF4-1", "sequence": { "sequence": "MAGQGGEPEELSLVDKGVRSLLEVSLSSDLHTLNMHCNRIARIEGLGHLRNLQHLDLSSNQIRRMEGLNALESLRSLNLSCNLITAVEGLEKLFNLTTLNLSHNHIHDLSGFQYLHGTHHKISCIDLRSNCINNINHLLQCTKGLQCLTNLTLEKYGNTNPVCYAAGYRETVLQALPQLAVLDGRNIHGELVESAEGNSSNLQCLEDILNSLVSSGSPSSKDQKALPLVTPHIDQALAYFRQRTKIPVQSSVSSSTERVSSSEPEKSILDKIQSEMRIQKLEDQISQILQKVSDASRREAPPNVLKAKRDTDPTSESEHETEKESSKKAVKRSKIPTYHRTTLSARRHLNHPKTKITDREEKSSSKRSPSHQRNSHLNSSSDTPDLEVVGRRANVLTGRQSNVEKVDEMNSNATKESTYRVLIQELDQEKERRWKAEQAEKKLVEHVKELQKHAKEEKNIQSMAVYTTERLKEMILKERDVKTRLQADLQQLKDETERLTNELNQAKNKEAEHQKAMQALEEALSKMETQRLQQRAIEMKQVQEAELKASANERELQLLRVSLRQQREKVKQLHELLILREREQRKELETRVALHGPEFQAAVSKEVAKEEQRHEQRVKDFQEKINMLNQKYTELEDEFRLALTIEAKRFKEVQEDFENVSADLAEHQQALFQFQQKEKEMTVLIQDLTSIVKEQKAKIAELVKSNQETTANLKSRTEELETVIEQNKEKAGQVELLKKENGKLISQLTAQESVIDGLRMERKIWGQELAQQGAHLSQDRGKLEAKIEVLTNEVEILKKQREQDGDAIRIKNKIVDDQTETIRRLKEGLQEKDKQIRKQHEENKLFQVQLDEKATEFEELMEKLERQNERKEQLKQHLEEKEVELSDIRRAHSALKKKWQGKDELLSQLEVQVKQMKEGFDMKEKKLIEERNKSLQAQR", "length": 939, "header": "tr|A0A8V0YIF4-1|A0A8V0YIF4_CHICK Computationally mapped isoform of Leucine-rich repeat and coiled-coil domain-containing protein 1 OS=Gallus gallus OX=9031 GN=LRRCC1 PE=3 SV=1 CANONICAL=A0A8V0YCU9-1" }, "locus": { "chromosome": "2", "start_pos": 122287346, "end_pos": 122270985, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031792.1", "url": "https://www.ensembl.org/id/ENSGALT00010031792.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018611.1", "url": "https://www.ensembl.org/id/ENSGALP00010018611.1" } ] } }, { "isoform_ac": "A0A8V0YL58-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCU9/entry#A0A8V0YL58-1", "sequence": { "sequence": "MAGQGGEPEELSLVDKGVRSLLEVSLSSDLHTLNMHCNRIARIEGLGHLRNLQHLDLSSNQIRRMEGLNALESLRSLNLSCNLITAVEGLEKLFNLTTLNLSHNHIHDLSGFQYLHGTHHKISCIDLRSNCINNINHLLQCTKGLQCLTNLTLEKYGNTNPVCYAAGYRETVLQALPQLAVLDGRNIHGELVESAEGNSSNLQCLEDILNSLVSSGSPSSKDQKALPLVTPHIDQALAYFRQRTKIPVQSSVSSSTERVSSSEPEKSILDKIQSEMRIQKLEDQISQILQKVSDASRREAPPNVLKAKRDTDPTSESEHETEKESSKKAVKRSKIPTYHRTTLSARRHLNHPKTKITDREEKSSSKRSPSHQRNSHLNSSSDTPDLEVVGRRANVLTGRQSNVEKVDEMNSNATKESTYRVLIQELDQEKERRWKAEQAEKKLVEHVKELQKHAKEEKNIQSMAVYTTERLKEMILKERDVKTRLQADLQQLKDETERLTNELNQAKNKEAEHQKAMQALEEALSKMETQRLQQRAIEMKQVQEAELKASANERELQLLRVSLRQQREKVKQLHELLILREREQRKELETRVALHGPEFQAAVSKEVAKEEQRHEQRVKDFQEKINMLNQKYTELEDEFRLALTIEAKRFKESRTEELETVIEQNKEKAGQVELLKKENGKLISQLTAQESVIDGLRMERKIWGQELAQQGAHLSQDRGKLEAKIEVLTNEVEILKKQREQDGDAIRIKNKIVDDQTETIRRLKEGLQEKDKQIRKQHEENKLFQVQLDEKATEFEELMEKLERQNERKEQLKQHLEEKEVELSDIRRAHSALKKKWQGKDELLSQLEVQVKQMKEGFDMKEKKLIEERNKSLQAQRIATEKLREMDDAFRKQLESVLAAHEAEIVQLANEKEKQVEAANEKVYYVEEEMRQLLQETANNKKAMEDKIRRITYVLSDIQQDL", "length": 962, "header": "tr|A0A8V0YL58-1|A0A8V0YL58_CHICK Computationally mapped isoform of Leucine-rich repeat and coiled-coil domain-containing protein 1 OS=Gallus gallus OX=9031 GN=LRRCC1 PE=3 SV=1 CANONICAL=A0A8V0YCU9-1" }, "locus": { "chromosome": "2", "start_pos": 122290248, "end_pos": 122270985, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031798.1", "url": "https://www.ensembl.org/id/ENSGALT00010031798.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018615.1", "url": "https://www.ensembl.org/id/ENSGALP00010018615.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "E9PTY0-1", "protein_name": "Leucine-rich repeat and coiled-coil domain-containing protein 1", "gene_name": "Lrrcc1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MATAAARMCVSWTKACTELSLDSSLHAINLHCNNISKITSIDHIWNLRHLDLSSNQISQIEGLNTLTKLCTLNLSCNLITRVEGLEALVNLTRLNLSYNHISDLSGLIPLHGLKYKLRYIDLHSNYIDSIHHLLQCTVGLHFLTNLILEKDGEGNPICLVPGYRAIILQTLPQLRILDCKNIFGEPVSLEEMNSSHLQCFEGLLDNLVSSDSPLNISEDEVVDNMSAPPIDVLPPLEEFTSTPEENVLTSLLSACSSEPEKINHENNFQNEMKLQKLDDQILQLLNETNNSLIDNVPEKDLRPKRDTDITSESDYGNRKECSRKVSRRTKIPYYTRTIQSIKHHNKNNGAFVSCNRKMRQPYLRDLYVRSSLVNCNNLREVDEQKNGMIKVDKSASNDNTYRSLVEQLDQEREMRWKAEQTEKKLMDYIDELHKQANEKKDVHSQAIITTDRLKDAIFKERHCKAQLEVIVHRLQNEIKKLTIELMKARDQQEDHIRHLRTLERALEKMEKQKAQQQQAQMRLIQEVELKASAADREINLLRTSLRQEKEQVQQLHDLLALKEQEHRQEIETREFFNDAEFQDALTKRLSKEERKHEQEVKEYQEKINILNQQYLDLENEFRIALTVEARRFKDVQDGFEDVATELAKSKHALIWAQRKENESSSLIKDLTSMVKEQKTKLSEVCKLKQEAAANLQNQINTLEILIEDDKQKSIQIELLKHEKNQLISELAAKESLIYGLRTERKVWGHELAYQGTSLSQSRGKLEAQIESLCRENESLRKTHESDCDALRIKCKIIEDQTETIRKLKDGLQEKDGQIKMLQEQITIIEKCSQEQLNEKTSQLDSIVEKLERHNERKEKLKQQLKAKELELEEIRKAYSTLNKKWHDKGELLSNLETQVKEVKEKFENKEKKLRAERDRSLELQKDAVEKLQNMDDAFKRQVDAIVEAHQTEITQLANEKQRYIECANLKVQQIEDEMRGLLEETCKNKKLMEEKIKQLACAISDIQKEM", "length": 1010 }, "evidence": [ { "id": "A0A8V0YCU9", "url": "https://omabrowser.org/oma/group/A0A8V0YCU9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1MZ78-1", "protein_name": "Leucine-rich repeat and coiled-coil domain-containing protein 1", "gene_name": "LRRCC1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MEAPGEAEVENEDGDSNCGDLCFMDKGLRSISELSLDSALHAINLHCNNISKITSIDHVWNLQHLDLSSNQISQIEGLNTLTKLCTLNLSCNLITRIEGLEALSNLTRLNLSYNHINDLSGLMPLHGIKHKLRYIDLHSNCIDSIHHLLQCTVGLHFLTNLILEKNGEDNPVCHLPGYRAVMLQTLPQLRILDCKNIFGEPINMAEINSSHLQCFEGLLDNLVSSESPLNISEDEITDGMPVAPPVGDTVPLDQFPSTPTDTGLTSLMSVCPSSEPEKVNHENDLQNEMKLQKLDDQILQLLSETSNSIIDNVPEKDPRPKRDTDVTSESDYGNRKECSKKTSRRSKIPYYSKTIQTIKHHSKNSSTFISCNRKMKPPFLKELYISSSLPNNSTLEESENQKTEIMKVNNDCPEDATYRALVEELDEEREKRWKAEQTEKKLMDYIDELHKHADEKKDIRSQALLTTDRLKEIIFKERNSKLQLEIMVHRLQNEIKKLTIELIKARDQQDDHIRHLRTLEKALEKMERQKGQQQAAQMRLIQEVELKAAAADREINLLRTSLHQEKEQVQQLHELLALKEKEHRKDIETREFFSEAEFQEALAKEIAKEERKHEQVIKEYQDKIDALNQQYMDLENEFRIALTVEARRFKDVKDGFENVATELAKSKHALVWAQRKENESSSLIKDLTCMVKEQKTKLAEVSKLKQETAANLQNQINTLEILIEDDKQKSIQIELLKQEKMQLISELAAKESLIYGLRTERKVWGHELALQGSSLVQNHGRVEAQLESLYRENECLRKASERDSDTIRIKCKIIDDQTETIGKLKECLQEREEQIKILHEKITEIQKCTQEQLEEKSSQLDEIVEKLERHNERKEKLKQQLKVKELELDEIRKAYSTLNQKWHDKGELLCHLEMQVKEVKENFENKERKLKAERDKSIELQKDAMEKLQSMDDAFKKQVDAIVEAHQNEIIQLANEKQKCIDSANLKVHRVEEEMRGLLEETCKNKKAMETKIKQLAFALSQIQQEI", "length": 1027 }, "evidence": [ { "id": "A0A8V0YCU9", "url": "https://omabrowser.org/oma/group/A0A8V0YCU9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1R597-1", "protein_name": "Leucine-rich repeat and coiled-coil domain-containing protein 1", "gene_name": "lrrcc1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAVGELCLIDKDISSLLEVSLNPSISSLNLHCNRLTKIEGLTTAWHIRHLDLSSNHICRIEGLASLSSLRTLNLSCNLITKVEGLDGLTNLTRLNLAYNQINDLTGLLYLHGANYKLKYLQLHSNRLDSMNHLLQCMVGLQNLKYITLSKDGAENPVCKMIGYREMVLQCLHQVTTLDGVDRMGNTCPLAEDSPMDVPGLEDFLEFLISSDTSVNGELAKSDAPLTTPRIDEVLTQFRQRGGKASTENQENEQRIKKLEQQVSHLIQKVPESDRVNSNSTAQPSVMRKAKRDTDQTSESECDSGKENQRHSRVLFHPRGSAGKKLSKDTKPKQSDCVAITQKQRSTKLTVCPRRSTSIQSSESADTSESVKRGPKIIKSGLKSSGQSQEETYKAIVEERDQERERRWKAEQAAKKLTEQVKNLQTRASEEKDLQSLALHTTDRLKEMLLKERSDRAGLQTRLQELEERYRSAVEQLEQVRNREEQHKRALCILEDSMSQAEALRVQQRAEEMKRTQELENKASAFKREVEILRASSRQHKEKLQQLHELLASREEMHRKELSARLLPGGTEFKEAVAKEVAATEQRFAQKQTDLEEKIRDARRQYAALEEEFRMALTIEAKRFTEVKEGFDQVSGELQELKSILNQSQQKEKQSASLVQELTAMVKEQKTRLAELLKAKREAVSEFKTRVQSLESRLEDDKRLNLQVELLRKDKSKLISQLTAQESVIDGLRAERRIWGQELAQQGASLAQDRGRLEARIEVLLSELESQKKQSERDSDSLRIKAKIVDDQTETIRKLKEALLERDEQMRKVSDESMQEQRNLKQQLEEEKSSALELRDSVEQLSLRKEELKQQLFDKEAELDEVKETYRASSKKWQEKAEVLNRLESQVKRMKEAFDSKEKTLIEERDKASLAHRAAVEKLHCVDDAFRRQLESLQASHQAELLRLANDKQKQIEKANQKVLQVEEEMRQLLEETESNKRVMEEKMRRLTQVLKDF", "length": 997 }, "evidence": [ { "id": "A0A8V0YCU9", "url": "https://omabrowser.org/oma/group/A0A8V0YCU9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q69ZB0-1", "protein_name": "Leucine-rich repeat and coiled-coil domain-containing protein 1", "gene_name": "Lrrcc1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEAAVCSEIEREDGDSSCGDVCFMDKGLHSISELSLDSSIHAINLHCNNISKISSIDHIWNLRHLDLSSNQISQIEGLNTLTKLCTLNLSCNLITRVEGLEALVNLTKLNLSYNHINDLSGLMPLHGLKYKLRYIDLHSNYIDSIHHLLQCTVGLHFLTNLILEKDGEGNPICLIPGYRAIILQTLPQLRILDCKNIFGEPVSLEEINSSHLQCLEGLLDNLVSSDSPLNISEDEVNDDVPAPPMDVLPSLKEFKSTPEDNVLASLLSVCPSSEPEKINQENDFQNEVKLQKLDDQILQLLNETNNSLIDNVPEKDLRPKRDTDITSESDYGNRRECSRKVPRRTKIPYYARTIQTIKHHNKNNGAFVSCNRKMRQPYLRDLYVRSSLVNCNNLRDLDEQKTGVIKVDKNFSDNSTYRSLVEQLDQEREMRWKAEQTEKKLMDYIDELHKQADEKKDVHSQALITTDRLKDAIFKERHCKAQLEIIVHRLQNEVKKLTIELMKARDQQEDHIRHLRTLERALEKMEKQKAQQQAAQIRLIQEVELKASAADREINLLRTSLHQEKQQVQQLHELLALKEQEHRQEIETRQFFTDAEFQDALTKRLCKEERKHEQEVKEYQEKIDILNQQYLDLENEFRIALTVEARRFKDVQDGFEDVATELAKSKHALIWAQRKENESSSLIKDLTCMVKEQKTKLSEVCKLKQEAAANLQNQINTLEILIEDDKQKSIQIELLKHEKTQLISELAAKESLIYGLRTERKVWGQELACQSSTLSQSRGKLEAQIESLCRENESLRKSHESDCDALRIKCKIIEDQNETIRKLKDSLQEKDGQIKLLQEQIALIEKCSQEQLNEKSSQLDSIVEKLERHNERKEKLKQQLKAKELELEEIRKAYSTLNKKWHDKGELLSHLEMQVKEVKEKFEDKERKLKAERDKSLELQKDAMEKLQNMDDAFRRQVDEIVEAHQAEIMQLANEKQKYIDCANLKVQQVEDEMRGLLDETCKNKKMMEEKIKQLACAISEIQKEM", "length": 1026 }, "evidence": [ { "id": "A0A8V0YCU9", "url": "https://omabrowser.org/oma/group/A0A8V0YCU9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9C099-1", "protein_name": "Leucine-rich repeat and coiled-coil domain-containing protein 1", "gene_name": "LRRCC1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEAAAAVVAAEAEVENEDGDSSCGDVCFMDKGLQSISELSLDSTLHAVNLHCNNISKIEAIDHIWNLQHLDLSSNQISRIEGLNTLTKLCTLNLSCNLITKVEGLEELINLTRLNVSYNHIDDLSGLIPLHGIKHKLRYIDLHSNRIDSIHHLLQCMVGLHFLTNLILEKDGDDNPVCRLPGYRAVILQTLPQLRILDCKNIFGEPVNLTEINSSQLQCLEGLLDNLVSSDSPLNISEDEIIDRMPVITAPIDELVPLEQFASTPSDAVLTSFMSVCQSSEPEKNNHENDLQNEIKLQKLDDQILQLLNETSNSIDNVLEKDPRPKRDTDITSESDYGNRKECNRKVPRRSKIPYDAKTIQTIKHHNKNYNSFVSCNRKMKPPYLKELYVSSSLANCPMLQESEKPKTEIIKVDQSHSEDNTYQSLVEQLDQEREKRWRAEQAENKLMDYIDELHKHANEKEDIHSLALLTTDRLKEIIFRERNSKGQLEVMVHKLQNEIKKLTVELMKAKDQQEDHLKHLRTLEKTLEKMERQKRQQQAAQIRLIQEVELKASAADREIYLLRTSLHREREQAQQLHQLLALKEQEHRKELETREFFTDADFQDALAKEIAKEEKKHEQMIKEYQEKIDVLSQQYMDLENEFRIALTVEARRFQDVKDGFENVATELAKSKHALIWAQRKENESSSLIKDLTCMVKEQKTKLAEVSKLKQETAANLQNQINTLEILIEDDKQKSIQIELLKHEKVQLISELAAKESLIFGLRTERKVWGHELAQQGSSLAQNRGKLEAQIESLSRENECLRKTNESDSDALRIKCKIIDDQTETIRKLKDCLQEKDEHIKRLQEKITEIEKCTQEQLDEKSSQLDEVLEKLERHNERKEKLKQQLKGKEVELEEIRKAYSTLNRKWHDKGELLCHLETQVKEVKEKFENKEKKLKAERDKSIELQKNAMEKLHSMDDAFKRQVDAIVEAHQAEIAQLANEKQKCIDSANLKVHQIEKEMRELLEETCKNKKTMEAKIKQLAFALNEIQQDM", "length": 1032 }, "evidence": [ { "id": "A0A8V0YCU9", "url": "https://omabrowser.org/oma/group/A0A8V0YCU9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCU9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCU9" } ], "pmid": "" }, { "name": "centriole", "id": "GO:0005814", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005814", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCU9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCU9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCU9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCU9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 100, "end_pos": 102, "annotation": "n_glycosylation_sequon" }, { "start_pos": 150, "end_pos": 152, "annotation": "n_glycosylation_sequon" }, { "start_pos": 198, "end_pos": 200, "annotation": "n_glycosylation_sequon" }, { "start_pos": 378, "end_pos": 380, "annotation": "n_glycosylation_sequon" }, { "start_pos": 412, "end_pos": 414, "annotation": "n_glycosylation_sequon" }, { "start_pos": 659, "end_pos": 661, "annotation": "n_glycosylation_sequon" }, { "start_pos": 78, "end_pos": 80, "annotation": "n_glycosylation_sequon" }, { "start_pos": 932, "end_pos": 934, "annotation": "n_glycosylation_sequon" }, { "start_pos": 95, "end_pos": 97, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YCU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCU9" }, { "id": "SM00446", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00446" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "U2A'/phosphoprotein 32 family A C-terminal", "eco_id": "ECO_0000259", "start_pos": 165, "end_pos": 183, "start_aa": "Ala", "end_aa": "Asp", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 100, "end_pos": 102 }, { "start_pos": 150, "end_pos": 152 }, { "start_pos": 198, "end_pos": 200 }, { "start_pos": 378, "end_pos": 380 }, { "start_pos": 412, "end_pos": 414 }, { "start_pos": 659, "end_pos": 661 }, { "start_pos": 78, "end_pos": 80 }, { "start_pos": 932, "end_pos": 934 }, { "start_pos": 95, "end_pos": 97 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YCV4-1", "uniprot_ac": "A0A8V0YCV4", "uniprot_id": "A0A8V0YCV4_CHICK", "mass": { "chemical_mass": 54087.0, "monoisotopic_mass": 54087.0 }, "refseq": {}, "gene_names": [ { "name": "HEATR8L5", "type": "recommended", "evidence": [ { "id": "A0A8V0YCV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCV4" } ] } ], "protein_names": [ { "name": "Maestro/Maestro-like HEAT-repeats domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A8V0YCV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCV4/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCV4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCV4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "HEATR8L5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCV4", "locus": {} } ], "crossref": [ { "id": "A0A8V0YCV4", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YCV4", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR011989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045206", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045206", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055406", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055406", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR23120", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23120", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23120:SF42", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23120:SF42", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF23227", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23227", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YCV4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCV4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YCV4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCV4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLACQFPRNVLTCVLTHLPQNDSTTLDMWKSMLSSTRSSERVLEVLFLVFKMGTLCGIPTAELDLLHLTVPEILGSIPRNLKRRRASLQETLFSLLDMLTRHFPRDVLMSVLTHLPQCDSTTLDIWESLLAPAATSERVLEELCSVLQDQQLCMTFNFTTVDFGLLRLTVMRPTEEILQELCNPDLFQMFLKIKSLPLLWLVLRGLVLLSERPETAREIRALLPDIMETLQFGNVHVTLNALNIFRNMMNHLGKMVLRPITLELADKLLHLFNHVSGEVRESSILLFQDVMEAVVWWQKGKMRKNVRRGLLPLLFRNSDETSSVAEAAGETLLACAKFLNWQELKHQAEKRNMVGIRECLLQQDRKRVDKYLQQSLLYLRDSQAAMRQEALSFIGLAWVYWDQSEEMRKKIYSVLHPLERDSHPTIRSLATSTILMLRYSRQQAKSGGGRLVELRCWPCNPLFRHKYD", "length": 468, "header": "tr|A0A8V0YCV4-1|A0A8V0YCV4_CHICK Isoform 1 of Maestro/Maestro-like HEAT-repeats domain-containing protein OS=Gallus gallus OX=9031 GN=HEATR8L5 PE=4 SV=1 CANONICAL=A0A8V0YCV4-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YCV4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCV4/entry#A0A8V0YCV4-1", "sequence": { "sequence": "MLACQFPRNVLTCVLTHLPQNDSTTLDMWKSMLSSTRSSERVLEVLFLVFKMGTLCGIPTAELDLLHLTVPEILGSIPRNLKRRRASLQETLFSLLDMLTRHFPRDVLMSVLTHLPQCDSTTLDIWESLLAPAATSERVLEELCSVLQDQQLCMTFNFTTVDFGLLRLTVMRPTEEILQELCNPDLFQMFLKIKSLPLLWLVLRGLVLLSERPETAREIRALLPDIMETLQFGNVHVTLNALNIFRNMMNHLGKMVLRPITLELADKLLHLFNHVSGEVRESSILLFQDVMEAVVWWQKGKMRKNVRRGLLPLLFRNSDETSSVAEAAGETLLACAKFLNWQELKHQAEKRNMVGIRECLLQQDRKRVDKYLQQSLLYLRDSQAAMRQEALSFIGLAWVYWDQSEEMRKKIYSVLHPLERDSHPTIRSLATSTILMLRYSRQQAKSGGGRLVELRCWPCNPLFRHKYD", "length": 468, "header": "tr|A0A8V0YCV4-1|A0A8V0YCV4_CHICK Isoform 1 of Maestro/Maestro-like HEAT-repeats domain-containing protein OS=Gallus gallus OX=9031 GN=HEATR8L5 PE=4 SV=1 CANONICAL=A0A8V0YCV4-1" }, "locus": { "chromosome": "Z", "start_pos": 56763264, "end_pos": 56758248, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028441.1", "url": "https://www.ensembl.org/id/ENSGALT00010028441.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016314.1", "url": "https://www.ensembl.org/id/ENSGALP00010016314.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 157, "end_pos": 159, "annotation": "n_glycosylation_sequon" }, { "start_pos": 21, "end_pos": 23, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YCV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCV4" }, { "id": "PF23227", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23227" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Maestro/Maestro-like HEAT-repeats", "eco_id": "ECO_0000259", "start_pos": 199, "end_pos": 437, "start_aa": "Leu", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 157, "end_pos": 159 }, { "start_pos": 21, "end_pos": 23 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YCX6-1", "uniprot_ac": "A0A8V0YCX6", "uniprot_id": "A0A8V0YCX6_CHICK", "mass": { "chemical_mass": 72996.0, "monoisotopic_mass": 72996.0 }, "refseq": { "ac": "NP_001026608", "name": "pumilio homolog 3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026608" }, "gene_names": [ { "name": "PUM3", "type": "recommended", "evidence": [ { "id": "A0A8V0YCX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCX6" } ] }, { "name": "KIAA0020", "type": "synonym", "evidence": [ { "id": "NP_001026608", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026608" } ] }, { "name": "PUM3", "type": "synonym", "evidence": [ { "id": "NP_001026608", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026608" } ] } ], "protein_names": [ { "name": "Pumilio homolog 3", "type": "recommended", "evidence": [ { "id": "A0A8V0YCX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCX6/entry#names_and_taxonomy" } ] }, { "name": "pumilio homolog 3", "type": "synonym", "evidence": [ { "id": "NP_001026608", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026608" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: HAEK01089823.1, SRR12888496.267774.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA103992290, SAMEA103992323 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000089.1. On Sep 23, 2021 this sequence version replaced NP_001026608.2.", "evidence": [ { "database": "RefSeq", "id": "NP_001026608", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026608" } ] }, { "annotation": "Inhibits the poly(ADP-ribosyl)ation activity of PARP1 and the degradation of PARP1 by CASP3 following genotoxic stress. Binds to double-stranded RNA or DNA without sequence specificity. Involved in development of the eye and of primordial germ cells.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCX6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCX6#function" }, { "database": "UniProtKB", "id": "ARBA00055542", "url": "https://www.uniprot.org/uniprotkb/ARBA00055542#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCX6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCX6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PUM3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCX6", "locus": { "chromosome": "Z", "start_pos": 27130926, "end_pos": 27156077, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010011384", "url": "https://www.ensembl.org/id/ENSGALG00010011384" } ] } } ], "crossref": [ { "id": "A0A8V0YCX6", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YCX6", "database": "AlphaFoldDB", "categories": [] }, { "id": "427350", "url": "https://www.ncbi.nlm.nih.gov/gene/427350", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001313", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001313", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012959", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012959", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033133", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033133", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040059", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040059", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:427350", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427350", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YGPEFSI", "url": "https://omabrowser.org/oma/group/YGPEFSI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YCW6", "url": "https://www.orthodb.org/?gene=A0A8V0YCW6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YCX6", "url": "https://www.orthodb.org/?gene=A0A8V0YCX6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YHM1", "url": "https://www.orthodb.org/?gene=A0A8V0YHM1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13389", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13389", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13389:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13389:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF08144", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08144", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001026608", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026608", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YCW6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCW6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YCW6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCW6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YCX6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCX6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YCX6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCX6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHM1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHM1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHM1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHM1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKAWNKKKFPGKNGKVSRGKQLRGKKKFKKDDDSVPLKTFHSKGDEEEKPKSISKKPVKGNLRPGRASVKQFKNKQQSEKLAKKRRYQDSTQGESDSKKPKWDDFKKKKKELKQSRQLNDRSNYDIIVKSKQIWESVRRKKCDKEKREKLMNELQKLLHGKIKNLAFAHDSTRVIQCFIQYGNDKQRQETFEELKDSLVELSKSKYSRNIVKKFLMYGTKQQIAEIIKSFKGHVKKMLRHAEASAVVEYAYNDKAILEQRNMLTEELYGNTFQVYKTPIVPTLDKVLEAQPEKREAILDEMKQILTPMAQKEAVIKHSLVHKVFLDFFTHALPKQRSEMIEAIREAVIYLAHTHDGARVAMHCLWHGTPKDRKVIVKTMKTYIEKIATGEFSHLVLLAAFDCIDDTKLVKQLIITELNASLPSLISNKHGKKVLLYLLSPRDPAHFVPEIITLLQQGDGNAYSKKSTELRRHELLEAISPPLLEYLQEHIQEVVMDKAAFVLVADILRTATGDIQPTLNAIANLAAEELVPGGRDGQLHIAEHPAGHLVLKWLIEQDEKMRESGKEGCFGRTLVECVGIENLKTWAEVNRGAIVLCCLLRSTDQKVTNAVKKGLKKIVPKLKLNKNVKGIEALLEKLT", "length": 638, "header": "tr|A0A8V0YCX6-1|A0A8V0YCX6_CHICK Isoform 1 of Pumilio homolog 3 OS=Gallus gallus OX=9031 GN=PUM3 PE=1 SV=1 CANONICAL=A0A8V0YCX6-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YCW6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCX6/entry#A0A8V0YCW6-1", "sequence": { "sequence": "MKAWNKKKFPGKNGKVSRGKQLRGKKKFKKDDDSVPLKTFHSKGDEEEKPKSISKKPVKGNLRPGRASVKQFKNKQQSEKLAKKRRYQDSTQGESDSKKPKWDDFKKKKKELKQSRQLNDRSNYDIIVKSKQIWESVRRKKCDKEKREKLMNELQKLLHGKIKNLAFAHDSTRVIQCFIQYGNDKQRQETFEELKDSLVELSKSKYSRNIVKKFLMYGTKQQIAEIIKSFKGHVKKMLRHAEASAVVEYAYNDKAILEQRNMLTEELYGNTFQVYKTPIVPTLDKVLEAQPEKREAILDEMKQILTPMAQKEAVIKHSLVHKVFLDFFTHALPKQRSEMIEAIREAVIYLAHTHDGARVAMHCLWHGTPKGEFSHLVLLAAFDCIDDTKLVKQLIITELNASLPSLISNKHGKKVLLYLLSPRDPAHFVPEIITLLQQGDGNAYSKKSTELRRHELLEAISPPLLEYLQEHIQEVVMDKAAFVLVADILRTATGDIQPTLNAIANLAAEELVPGGRDGQLHIAEHPAGHLVLKWLIEQDEKMRESGKEGCFGRTLVECVGIENLKTWAEVNRGAIVLCCLLRSTDQKVTNAVKKGLKKIVPKLKLNKNVKGIEALLEKLT", "length": 620, "header": "tr|A0A8V0YCW6-1|A0A8V0YCX6_CHICK Computationally mapped isoform of Pumilio homolog 3 OS=Gallus gallus OX=9031 GN=PUM3 PE=1 SV=1 CANONICAL=A0A8V0YCX6-1" }, "locus": { "chromosome": "Z", "start_pos": 27155676, "end_pos": 27131722, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027229.1", "url": "https://www.ensembl.org/id/ENSGALT00010027229.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015502.1", "url": "https://www.ensembl.org/id/ENSGALP00010015502.1" } ] } }, { "isoform_ac": "A0A8V0YCX6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCX6/entry#A0A8V0YCX6-1", "sequence": { "sequence": "MKAWNKKKFPGKNGKVSRGKQLRGKKKFKKDDDSVPLKTFHSKGDEEEKPKSISKKPVKGNLRPGRASVKQFKNKQQSEKLAKKRRYQDSTQGESDSKKPKWDDFKKKKKELKQSRQLNDRSNYDIIVKSKQIWESVRRKKCDKEKREKLMNELQKLLHGKIKNLAFAHDSTRVIQCFIQYGNDKQRQETFEELKDSLVELSKSKYSRNIVKKFLMYGTKQQIAEIIKSFKGHVKKMLRHAEASAVVEYAYNDKAILEQRNMLTEELYGNTFQVYKTPIVPTLDKVLEAQPEKREAILDEMKQILTPMAQKEAVIKHSLVHKVFLDFFTHALPKQRSEMIEAIREAVIYLAHTHDGARVAMHCLWHGTPKDRKVIVKTMKTYIEKIATGEFSHLVLLAAFDCIDDTKLVKQLIITELNASLPSLISNKHGKKVLLYLLSPRDPAHFVPEIITLLQQGDGNAYSKKSTELRRHELLEAISPPLLEYLQEHIQEVVMDKAAFVLVADILRTATGDIQPTLNAIANLAAEELVPGGRDGQLHIAEHPAGHLVLKWLIEQDEKMRESGKEGCFGRTLVECVGIENLKTWAEVNRGAIVLCCLLRSTDQKVTNAVKKGLKKIVPKLKLNKNVKGIEALLEKLT", "length": 638, "header": "tr|A0A8V0YCX6-1|A0A8V0YCX6_CHICK Isoform 1 of Pumilio homolog 3 OS=Gallus gallus OX=9031 GN=PUM3 PE=1 SV=1 CANONICAL=A0A8V0YCX6-1" }, "locus": { "chromosome": "Z", "start_pos": 27155676, "end_pos": 27131722, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027244.1", "url": "https://www.ensembl.org/id/ENSGALT00010027244.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015513.1", "url": "https://www.ensembl.org/id/ENSGALP00010015513.1" } ] } }, { "isoform_ac": "A0A8V0YHM1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCX6/entry#A0A8V0YHM1-1", "sequence": { "sequence": "MKAWNKKKFPGKNGKVSRGKQLRGKKKFKKDDDSVPLKTFHSKGDEEEKPKSISKKPVKGNLRPGRASVKQFKNKQQSEKLAKKRRYQDSTQGESDSKKPKWDDFKKKKKELKQSRQLNDRSNYDIIVKSKQIWESVRRKKCDKEKREKLMNELQKLLHGKIKNLAFAHDSTRVIQCFIQYGNDKQRQETFEELKGIFSCLPFICMVLTKQQIAEIIKSFKGHVKKMLRHAEASAVVEYAYNDKAILEQRNMLTEELYGNTFQVYKTPIVPTLDKVLEAQPEKREAILDEMKQILTPMEMIEAIREAVIYLAHTHDGARVAMHCLWHGTPKDRKVIVKTMKTYIEKIATGEFSHLVLLAAFDCIDDTKLVKQLIITELNASLPSLISNKHGKKVLLYLLSPRDPAHFVPEIITLLQQGDGNAYSKKSTELRRHELLEAISPPLLEYLQEHIQEVVMDKAAFVLVADILRTATGDIQPTLNAIANLAAEELVPGGRDGQLHIAEHPAGHLVLKWLIEQDEKMRESGKEGCFGRTLVECVGIENLKTWAEVNRGAIVLCCLLRSTDQKVTNAVKKGLKKIVPKLKLNKNVKGIEALLEKLT", "length": 599, "header": "tr|A0A8V0YHM1-1|A0A8V0YHM1_CHICK Computationally mapped isoform of Pumilio RNA binding family member 3 OS=Gallus gallus OX=9031 GN=PUM3 PE=1 SV=1 CANONICAL=A0A8V0YCX6-1" }, "locus": { "chromosome": "Z", "start_pos": 27155676, "end_pos": 27131722, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027249.1", "url": "https://www.ensembl.org/id/ENSGALT00010027249.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015516.1", "url": "https://www.ensembl.org/id/ENSGALP00010015516.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:427350", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427350", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A9J7GRI4-1", "protein_name": "Pumilio homolog 3", "gene_name": "Pum3", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MGGKSILGRAEGIAMMEVKEKKKFTGKSPKTAQGKTRFHKNRDSGSSKTFPQKVVKEGGPKVSSKNFEKGATKPGKKGVKQFKNKPQGGKGPKDKFQKPNTFNKKRKFQPDGKSDESAAKKPKWDDFKKKKKELKQSRQLSDKTNYDIVVRAKHIWESLRRKDCDKEKRRKLMSDLQKLIQGKIKTIAFAHDSTRVIQCFIQYGNEEQRKQAFEELQGDLVELSKAKYSRNIVKKFLMYGSKPQIAEIIRSFKGHVRKMLRHSEASAIVEYAYNDKAILEQRNMLTEELYGNTFQLYKSADHPTLGKVLEVQPGKLELIMDEMKQILTPMAQKEAVIKHSLVHKVFLDFFTYAPPKLRSELIEAIREAVVYLAHTHDGARVAMHCLWHGTPKDRKVIVKTMKTYVEKVANGQYSHLVLLAAFDCIDDTKLVKQIIISEIISSLPSIVNDKYGRKVLLYLLSPRDPAHTVREIIELLQKGDGNAHSKKDTAIRRRELLESISPALLNHLQGHAREVVLDKSACVLVSDILGSATGDVQPAMDAIASLAAVELHPGGKDGELHVAEHPAGHLVLKWLIEQDKKMKDNGREGCFAKTLIERVGMKNLKSWASINRGAIILSSLLQSCDQEVVNKVKAGLKSLIPTLEKNKSTSKGVEILLEKLTA", "length": 662 }, "evidence": [ { "id": "A0A8V0YCX6", "url": "https://omabrowser.org/oma/group/A0A8V0YCX6/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "F1SJG9-1", "protein_name": "Pumilio homolog 3", "gene_name": "PUM3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MMEVKGKKKFTGKGTKTSQEKNRFHKNNGSGSSKTFPQKVVKEGEPKITSKNFEKSATKPGKKGVKQFKNKQQGDKIPKNKFQQGNKFNRKRKIQPDSKNDGSAAKKPKWDEFKKKKKELKQSRQLSDKANYDIVVRAKQIWEILRRKDCNKEKRVKLMSDLQKLIQGKIKTIAFAHDSTRVIQCYIQYGTEEQRKQAFEELRGDLVELSKAKYSRNIVKKFLMYGNKAQIAEIMRSFKGHVRKMLRHAEASAIVEYAYNDKAILEQRNMLTEELYGNTFQLYKSADCPTLDKVLEVQPEKLELIMDEMKQILTPMAQKEAVIKHSLVHKVFLDFFTHAPPKLRSEMIEAIREAVIYLAHTHDGARVAMHCLWHGTPKDRKVIVKTMKTYVEKVANGQYSHLVLLAAFDCIDDTKLVKQIIISEIINSLPNIVNDKYGRKVLLYLLSPRDPAHTVREIIEVLQKGDGNAHSKKDTEIRRRELLESISPALLSYLQGHAQEVMLDKSACVLVSDILGAAIGDVQPAMNAIASLAAAELHPGGKDGELHIAEHPAGHLVLKWLIEQDKKMKESGREGCFAKTLVEHVGMKNLKSWASVNRGAIILSSLLQSSDQEVANEVKAGLKSLIPTLEKNKNTSKGIEMLLEKLTA", "length": 648 }, "evidence": [ { "id": "A0A8V0YCX6", "url": "https://omabrowser.org/oma/group/A0A8V0YCX6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q04373-1", "protein_name": "Pumilio homology domain family member 6", "gene_name": "PUF6", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MAPLTKKTNGKRSAKEVSHSEKKLAKKPRISIDSSDEESELSKKEDAVSSSSDDDDLDDLSTSDSEAEEEADELDISDDSEEHENENEEKEGKDKSEGGENGNHTEQRKLLKERKMQRKSGTQVQQIKSVWERLRVKTPPLPKQIREKLSNEIWELSKDCISDLVLKHDASRIVQTLVKYSSKDRREQIVDALKGKFYVLATSAYGKYLLVKLLHYGSRSSRQTIINELHGSLRKLMRHREGAYVVEDLFVLYATHEQRQQMIKEFWGSEYAVFRETHKDLTIEKVCESSIEKRNIIARNLIGTITASVEKGSTGFQILHAAMREYVKIANEKEISEMIELLHEQFAELVHTPEGSDVACTLVARANAKERKLILKALKNHAEKLIKNEYGNIVFITILNCVDDTVLVFKTFSPTVKEHLQEFIIDKFGRRPWLYILLGLDGKYFSPIVKNELLRYIELSKATSKKDPLQRRHELLSKFAPMFLSTISKDYSSILTENLGCQFIAEVLINDELYAQLNEKDQEKYQQVLNNILTTFKGDITEEEHPIHRAFSTRLLKALIQGGKWNNKEKKVIPLKNVQGLGVPFAEKLYDEIIDSSNLLEWINNADSSFTIVALYETLKDQKEGKPFLKDLRGVQSKITTDESNKGSQLLAKLLK", "length": 656 }, "evidence": [ { "id": "A0A8V0YCX6", "url": "https://omabrowser.org/oma/group/A0A8V0YCX6/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q15397-1", "protein_name": "Pumilio homolog 3", "gene_name": "PUM3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEVKGKKQFTGKSTKTAQEKNRFHKNSDSGSSKTFPTRKVAKEGGPKVTSRNFEKSITKLGKKGVKQFKNKQQGDKSPKNKFQPANKFNKKRKFQPDGRSDESAAKKPKWDDFKKKKKELKQSRQLSDKTNYDIVVRAKQMWEILRRKDCDKEKRVKLMSDLQKLIQGKIKTIAFAHDSTRVIQCYIQYGNEEQRKQAFEELRDDLVELSKAKYSRNIVKKFLMYGSKPQIAEIIRSFKGHVRKMLRHAEASAIVEYAYNDKAILEQRNMLTEELYGNTFQLYKSADHRTLDKVLEVQPEKLELIMDEMKQILTPMAQKEAVIKHSLVHKVFLDFFTYAPPKLRSEMIEAIREAVVYLAHTHDGARVAMHCLWHGTPKDRKVIVKTMKTYVEKVANGQYSHLVLLAAFDCIDDTKLVKQIIISEIISSLPSIVNDKYGRKVLLYLLSPRDPAHTVREIIEVLQKGDGNAHSKKDTEVRRRELLESISPALLSYLQEHAQEVVLDKSACVLVSDILGSATGDVQPTMNAIASLAATGLHPGGKDGELHIAEHPAGHLVLKWLIEQDKKMKENGREGCFAKTLVEHVGMKNLKSWASVNRGAIILSSLLQSCDLEVANKVKAALKSLIPTLEKTKSTSKGIEILLEKLST", "length": 648 }, "evidence": [ { "id": "A0A8V0YCX6", "url": "https://omabrowser.org/oma/group/A0A8V0YCX6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q562C7-1", "protein_name": "Pumilio homolog 3", "gene_name": "Pum3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEVKGKKKITGKSPQTSQGKNKFHKNSESSSAKAFPRKAAKEGGPKVTSKNFEKGATKPGKKRVKQFKNKPQGGKGPKDKFQKANKFNKKRKFQPDGKSDESAAKKPKWDDFKKKKKELKQNRQLSDKTNYDVVVRAKHIWESLRRKDCDKEKRVKLMSDLQKLIQGKIKTIAFAHDSTRVIQCLIQYGSEEQRKWAFEELQGDLVELSKAKYSRNIVKKFLMYGSKPQIAEIIRSFKGHVRKMLRHSEASAIVEYAYNDKAILEQRNMLTEELYGNTFQLYKSADHPTLEKVLEVQPGKLELILDEMKQILTPMAQKEAVIKHSLVHKVFLDFFTYAPPKLRSELIEAIREAVVYLAHTHDGARVAMHCLWHGTPKDRKVIVKTMKTYVEKIANGQYSHLVLLAAFDCIDDTKLVKQIIISEVISSLPSIVNDKYGRKVLLYLLSPRAPAHLVPEIIQLLQKGDGNAHSKKDTAIRRRELLESISPALLSYLQGHTREVVLDKSVCVLVSDILGSATGDAQPAMDAIAGLAAEELYPGGKDGELHIAEHPAGHLVLKWLIEQDKKIKENGKEGCFAKTLVECVGMKNLKSWASINRGAIVLSSLLQSCDQDVVNKVKAGLKTLIPTLEKTKSTSKGIQTLLEKLTA", "length": 647 }, "evidence": [ { "id": "A0A8V0YCX6", "url": "https://omabrowser.org/oma/group/A0A8V0YCX6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8BKS9-1", "protein_name": "Pumilio homolog 3", "gene_name": "Pum3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEVKGKKKFTGKSPQTSQGKNKFHKNSESSSSKTFPRKAVKEGGPKVTSKNFEKGATKPGKKGVKQFKNKPQGGKGPKDKFQKANKFSKKRKFQPDGESDESGAKKPKWDDFKKKKKELKQSRQLSDKTNYDIVVRAKHIWESLRRKDCDKEKRVKLMSDLQKLIQGKIKTIAFAHDSTRVIQCFIQYGNEEQRKQAFQELQGDLVELSKAKYSRNIVKKFLMYGSKPQVAEIIRSFKGHVRKMLRHSEASAIVEYAYNDKAILEQRNMLTEELYGNTFQLYKSADHPTLDKVLELQPAKLELIMDEMKQILTPMAQKEAVIKHSLVHKVFLDFFTYAPPKPRSELIEAIREAVVYLAHTHDGARVAMHCLWHGTPKDRKVIVKTMKTYVEKVANGQYSHLVLLAAFDCIDDTKLVKQIIISEIISSLPSIVNDKYGRKVLLYLMSPRDPAHTVPELIELLQKGDGNAHSKKDTAIRRRELLESISPALLSYLQGHTQEVVLDKSACVLVSDMLGSATGDVQPAMDAIASLAAAELHPGGKDGELHVAEHPAGHLVLKWLLEQDKKMKESGKEGCFAKTLVERVGMKNLKSWASINRGAIILSSLLQSCDQEVVNKVKGGLKPLIPTLEKNKSSSRGIQTLLEKLTA", "length": 647 }, "evidence": [ { "id": "A0A8V0YCX6", "url": "https://omabrowser.org/oma/group/A0A8V0YCX6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "X1WGX5-1", "protein_name": "Pumilio homolog 3", "gene_name": "pum3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEGKPRKKSFTPRDGKKPSFKSKGKPGGKPQGKRPFKPHNNDKGKGFRKSGGEGGPQKFNRKPTDGKFAKKRKFPGDRIKQEEGDERKKPKWDEFKQKKKELKLNRQQTDRKESYQIVSRAKQVWEMVRRKDCDKQKRTKLMKELQDLVKGKIKTIAFAHDSTRVLQCFIQFGSDKQRKEVFDELKEHIVELSKSKYARNIVKKFLMYGSKEQVGEVMLAFKGKVRQMLRHSEASSVVEYAYNDKAILSQRLMLTEELYGNTFTVLKSSVCPTLEKVLEANPGKLESILDEMKQILTPMAQKEAVIKHSLVHKVFLDFFEHAPDKQRTEMIESIREAVVYMAHTHDGARVTMHCLWHGTTKDRKVIVKTMKSYIAKFAMGEYAHLVLLAAFDCIDDTKLVKQIIISEMVSSLSEIISNKHGKKVLLYLLSPRDPAHLLPEIIQVLEKGDGNAHSKKDVLIRRKELLEAASPSLLNHLCENAQSMVMDKSCCVVVSDILGSAVGDLRPAMEAVAALADGPLIPGGKDGQLHMAEHPAGHLVLKWLIEQDTKMKDTEREERFSRILLEKVGLENLKTWASVNRGAIILCCLLQSADESVAEEVKAMLKSSIPELQRLQNSKGIEVLLEKLA", "length": 629 }, "evidence": [ { "id": "A0A8V0YCX6", "url": "https://omabrowser.org/oma/group/A0A8V0YCX6/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCX6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCX6" } ], "pmid": "" }, { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCX6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCX6" } ], "pmid": "" }, { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCX6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCX6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCX6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCX6" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCX6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCX6" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCX6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCX6" } ], "pmid": "" }, { "name": "chromosome", "id": "GO:0005694", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005694", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCX6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCX6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "regulation of translation", "id": "GO:0006417", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006417", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCX6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCX6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 418, "end_pos": 420, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YCX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCX6" }, { "id": "PS50303", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50303" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PUM-HD", "eco_id": "ECO_0000259", "start_pos": 129, "end_pos": 502, "start_aa": "Lys", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 418, "end_pos": 420 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YE65-1", "uniprot_ac": "A0A8V0YE65", "uniprot_id": "A0A8V0YE65_CHICK", "mass": { "chemical_mass": 39182.0, "monoisotopic_mass": 39182.0 }, "refseq": { "ac": "XP_001233737", "name": "proline-serine-threonine phosphatase-interacting protein 2 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001233737" }, "gene_names": [ { "name": "PSTPIP2", "type": "recommended", "evidence": [ { "id": "A0A8V0YE65", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE65" } ] }, { "name": "PSTPIP2", "type": "synonym", "evidence": [ { "id": "XP_001233737", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001233737" } ] } ], "protein_names": [ { "name": "Proline-serine-threonine phosphatase-interacting protein 2", "type": "recommended", "evidence": [ { "id": "A0A8V0YE65", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE65/entry#names_and_taxonomy" } ] }, { "name": "proline-serine-threonine phosphatase-interacting protein 2 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_001233737", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001233737" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052572.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_001233737.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_001233737", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001233737" } ] }, { "annotation": "Binds to F-actin. May be involved in regulation of the actin cytoskeleton.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCW9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCW9#function" }, { "database": "UniProtKB", "id": "ARBA00058685", "url": "https://www.uniprot.org/uniprotkb/ARBA00058685#function" }, { "database": "UniProtKB", "id": "A0A8V0YE65", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE65#function" }, { "database": "UniProtKB", "id": "A0A8V0YL39", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL39#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YE65", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE65" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PSTPIP2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE65", "locus": { "chromosome": "Z", "start_pos": 2508873, "end_pos": 2493427, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012108", "url": "https://www.ensembl.org/id/ENSGALG00010012108" } ] } } ], "crossref": [ { "id": "A0A8V0YE65", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YE65", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd07672", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07672", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "770399", "url": "https://www.ncbi.nlm.nih.gov/gene/770399", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001060", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001060", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027267", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027267", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR031160", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031160", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042694", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042694", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:770399", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:770399", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "EEADQNM", "url": "https://omabrowser.org/oma/group/EEADQNM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y7X5", "url": "https://www.orthodb.org/?gene=A0A8V0Y7X5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YCW9", "url": "https://www.orthodb.org/?gene=A0A8V0YCW9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YE65", "url": "https://www.orthodb.org/?gene=A0A8V0YE65", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YL39", "url": "https://www.orthodb.org/?gene=A0A8V0YL39", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23065", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23065", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23065:SF9", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23065:SF9", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00611", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00611", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_001233737", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001233737", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Y7X5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y7X5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y7X5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y7X5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YCW9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCW9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YCW9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCW9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YE65", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE65", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YE65-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE65-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YL39", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL39", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YL39-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL39-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRETLFRDHFWSSDLTSTVGYDSIIQHLNDGRKNCKEFEDFLKERAVIEEKYGKELINLSKKKPCGQTELNTLKRSLDAFKQQIDNVGQGHIQLAQTLREEAKKMEDFREKQKLHRKKIELIMEAIHKNRNLQYKKTMEAKRLYEQRCRDKDEAEQAVHRNANLVTQKQQEKLFLKLAQTKSSLEDSDRNYQQSITSLEKIREEWQKEHIKACEFFETQECERISYFRNALWLHVNQLSQSCVQNDEKYEEIRKSLEMCSIEKDIEFFVNLRKTGSSAPAPVAYENYYNAQRNATPVRSPASVPISRRGPLPTPTSGPGDPDYATIDGYSLIHH", "length": 334, "header": "tr|A0A8V0YE65-1|A0A8V0YE65_CHICK Isoform 1 of Proline-serine-threonine phosphatase-interacting protein 2 OS=Gallus gallus OX=9031 GN=PSTPIP2 PE=4 SV=1 CANONICAL=A0A8V0YE65-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Y7X5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE65/entry#A0A8V0Y7X5-1", "sequence": { "sequence": "MRETLFRDHFWSSDLTSTVGYDSIIQHLNDGRKNCKEFEDFLKESTLKRSLDAFKQQIDNVGQGHIQLAQTLREEAKKMEDFREKQKLHRKKIELIMEAIHKNRNLQYKKTMEAKRLYEQRCRDKDEAEQAVHRNANLVTQKQQEKLFLKLAQTKSSLEDSDRNYQQSITSLEKIREEWQKEHIKACEFFETQECERISYFRNALWLHVNQLSQSCVQNDEKYEEIRKSLEMCSIEKDIEFFVNLRKTGSSAPAPVAYENYYNAQRNATPVRSPASVPISRRGPLPTPTSGPGDPDYATIDGYSLIHH", "length": 308, "header": "tr|A0A8V0Y7X5-1|A0A8V0Y7X5_CHICK Computationally mapped isoform of Proline-serine-threonine phosphatase interacting protein 2 OS=Gallus gallus OX=9031 GN=PSTPIP2 PE=4 SV=1 CANONICAL=A0A8V0YE65-1" }, "locus": { "chromosome": "Z", "start_pos": 2507704, "end_pos": 2493575, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029024.1", "url": "https://www.ensembl.org/id/ENSGALT00010029024.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016783.1", "url": "https://www.ensembl.org/id/ENSGALP00010016783.1" } ] } }, { "isoform_ac": "A0A8V0YCW9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE65/entry#A0A8V0YCW9-1", "sequence": { "sequence": "MVILANATSKSSDLTSTVGYDSIIQHLNDGRKNCKEFEDFLKERAVIEEKYGKELINLSKKKPCGQTELNTLKRSLDAFKQQIDNVGQGHIQLAQTLREEAKKMEDFREKQKLHRKKIELIMEAIHKNRNLQYKKTMEAKRLYEQRCRDKDEAEQAVHRNANLVTQKQQEKLFLKLAQTKSSLEDSDRNYQQSITSLEKIREEWQKEHIKACEFFETQECERISYFRNALWLHVNQLSQSCVQNDEKYEEIRKSLEMCSIEKDIEFFVNLRKTGSSAPAPVAYENYYNAQRNATPVRSPASVPISRRGPLPTPTSGPGDPDYATIDGYSLIHH", "length": 333, "header": "tr|A0A8V0YCW9-1|A0A8V0YE65_CHICK Computationally mapped isoform of Proline-serine-threonine phosphatase-interacting protein 2 OS=Gallus gallus OX=9031 GN=PSTPIP2 PE=4 SV=1 CANONICAL=A0A8V0YE65-1" }, "locus": { "chromosome": "Z", "start_pos": 2507704, "end_pos": 2494312, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029023.1", "url": "https://www.ensembl.org/id/ENSGALT00010029023.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016782.1", "url": "https://www.ensembl.org/id/ENSGALP00010016782.1" } ] } }, { "isoform_ac": "A0A8V0YE65-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE65/entry#A0A8V0YE65-1", "sequence": { "sequence": "MRETLFRDHFWSSDLTSTVGYDSIIQHLNDGRKNCKEFEDFLKERAVIEEKYGKELINLSKKKPCGQTELNTLKRSLDAFKQQIDNVGQGHIQLAQTLREEAKKMEDFREKQKLHRKKIELIMEAIHKNRNLQYKKTMEAKRLYEQRCRDKDEAEQAVHRNANLVTQKQQEKLFLKLAQTKSSLEDSDRNYQQSITSLEKIREEWQKEHIKACEFFETQECERISYFRNALWLHVNQLSQSCVQNDEKYEEIRKSLEMCSIEKDIEFFVNLRKTGSSAPAPVAYENYYNAQRNATPVRSPASVPISRRGPLPTPTSGPGDPDYATIDGYSLIHH", "length": 334, "header": "tr|A0A8V0YE65-1|A0A8V0YE65_CHICK Isoform 1 of Proline-serine-threonine phosphatase-interacting protein 2 OS=Gallus gallus OX=9031 GN=PSTPIP2 PE=4 SV=1 CANONICAL=A0A8V0YE65-1" }, "locus": { "chromosome": "Z", "start_pos": 2507704, "end_pos": 2493575, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029026.1", "url": "https://www.ensembl.org/id/ENSGALT00010029026.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016785.1", "url": "https://www.ensembl.org/id/ENSGALP00010016785.1" } ] } }, { "isoform_ac": "A0A8V0YL39-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE65/entry#A0A8V0YL39-1", "sequence": { "sequence": "MRETLFRDHFWIRLAKRRPKLRTGCVFSEISSLQEESSDLTSTVGYDSIIQHLNDGRKNCKEFEDFLKERAVIEEKYGKELINLSKKKPCGQTELNTLKRSLDAFKQQIDNVGQGHIQLAQTLREEAKKMEDFREKQKLHRKKIELIMEAIHKNRNLQYKKTMEAKRLYEQRCRDKDEAEQAVHRNANLVTQKQQEKLFLKLAQTKSSLEDSDRNYQQSITSLEKIREEWQKEHIKACEFFETQECERISYFRNALWLHVNQLSQSCVQNDEKYEEIRKSLEMCSIEKDIEFFVNLRKTGSSAPAPVAYENYYNAQRNATPVRSPASVPISRRGPLPTPTSGPGDPDYATIDGYSLIHH", "length": 359, "header": "tr|A0A8V0YL39-1|A0A8V0YL39_CHICK Computationally mapped isoform of Proline-serine-threonine phosphatase-interacting protein 2 OS=Gallus gallus OX=9031 GN=PSTPIP2 PE=4 SV=1 CANONICAL=A0A8V0YE65-1" }, "locus": { "chromosome": "Z", "start_pos": 2507704, "end_pos": 2493575, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029025.1", "url": "https://www.ensembl.org/id/ENSGALT00010029025.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016784.1", "url": "https://www.ensembl.org/id/ENSGALP00010016784.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 313, "start_aa": "Thr", "end_pos": 313, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr313", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 315, "start_aa": "Thr", "end_pos": 315, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr315", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:770399", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:770399", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A4X1UTD4-1", "protein_name": "Proline-serine-threonine phosphatase-interacting protein 2", "gene_name": "PSTPIP2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTGSLFKGNFWSSDILSTIGYDTIIQHLNNGRKNCKEFEDFLKERASIEEKYGKDLLNLSRKKPCGQSETNTLKRALEVFKQQVDNVAQSHIQLAQTLREEARKMEEFREKQKLQRKKTELIMDAVHKQKSLQFKKTMDAKKNYEQKCRDKDEAEQAVHRSANLVNPKQQEKLFVKLATSKTAVEDSDKAYMLHVNTLDKVREEWQSEHIKACEVFETQECERINFFRNALWLHLNQLSQQCVTSDDMYEEVRKSLEMCSIEKDIEYFVNQRKTGQTPPAPIMYENFYCPQKNAAPPGKATGPNLPRRGPLPVPKSLPDDPDYSLLDNYSLIYQ", "length": 334 }, "evidence": [ { "id": "A0A8V0YE65", "url": "https://omabrowser.org/oma/group/A0A8V0YE65/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q99M15-1", "protein_name": "Proline-serine-threonine phosphatase-interacting protein 2", "gene_name": "Pstpip2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTGSLFKGNFWSTDILSTIGYDSIIQHLNNGRKNCKEFEDFLKERASIEEKYGKDLLNLSRKKPCGQSEINTLKRALEVFKQQVDNVAQCHIQLAQTLREEARKMEEFREKQKLQRKKTETIMDAAHKQRNAQFKKAMDAKKNYEQKCRDKDEAEQAVHRSANVANQRQQEKLFVKLATSKTAVEDSDKAYMLHINMLEKVREDWQSEHIKACEVFEAQECERINFFRNALWLHLNQLSQQCVANDEMYEQVRKSLETCSIEKDIQYFVNQRKTGQTPPAPIMYENFYSPQRNAAPPGKTTGPNPARRGPLPVPKRIPDDPDYSVVEDYSLLYQ", "length": 334 }, "evidence": [ { "id": "A0A8V0YE65", "url": "https://omabrowser.org/oma/group/A0A8V0YE65/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9H939-1", "protein_name": "Proline-serine-threonine phosphatase-interacting protein 2", "gene_name": "PSTPIP2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTRSLFKGNFWSADILSTIGYDNIIQHLNNGRKNCKEFEDFLKERAAIEERYGKDLLNLSRKKPCGQSEINTLKRALEVFKQQVDNVAQCHIQLAQSLREEARKMEEFREKQKLQRKKTELIMDAIHKQKSLQFKKTMDAKKNYEQKCRDKDEAEQAVSRSANLVNPKQQEKLFVKLATSKTAVEDSDKAYMLHIGTLDKVREEWQSEHIKACEAFEAQECERINFFRNALWLHVNQLSQQCVTSDEMYEQVRKSLEMCSIQRDIEYFVNQRKTGQIPPAPIMYENFYSSQKNAVPAGKATGPNLARRGPLPIPKSSPDDPNYSLVDDYSLLYQ", "length": 334 }, "evidence": [ { "id": "A0A8V0YE65", "url": "https://omabrowser.org/oma/group/A0A8V0YE65/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YE65", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE65" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YE65", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE65" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YE65", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE65" } ], "pmid": "" }, { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YE65", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE65" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YE65", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE65" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 293, "end_pos": 295, "annotation": "n_glycosylation_sequon" }, { "start_pos": 58, "end_pos": 60, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YE65", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE65" }, { "id": "PS51741", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51741" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "F-BAR", "eco_id": "ECO_0000259", "start_pos": 4, "end_pos": 264, "start_aa": "Thr", "end_aa": "Asp", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 313, 315 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 293, "end_pos": 295 }, { "start_pos": 58, "end_pos": 60 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { 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"field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YCX9-1", "uniprot_ac": "A0A8V0YCX9", "uniprot_id": "A0A8V0YCX9_CHICK", "mass": { "chemical_mass": 65122.0, "monoisotopic_mass": 65122.0 }, "refseq": { "ac": "XP_015135620", "name": "potassium voltage-gated channel subfamily V member 2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015135620" }, "gene_names": [ { "name": "KCNV2", "type": "recommended", "evidence": [ { "id": "A0A8V0YCX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCX9" } ] }, { "name": "KCNV2", "type": "synonym", "evidence": [ { "id": "XP_015135620", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015135620" } ] } ], "protein_names": [ { "name": "Potassium voltage-gated channel subfamily V member 2", "type": "recommended", "evidence": [ { "id": "A0A8V0YCX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCX9/entry#names_and_taxonomy" } ] }, { "name": "Voltage-gated potassium channel subunit Kv8.2", "type": "synonym", "evidence": [ { "id": "A0A8V0YCX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCX9/entry#names_and_taxonomy" } ] }, { "name": "potassium voltage-gated channel subfamily V member 2", "type": "synonym", "evidence": [ { "id": "XP_015135620", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015135620" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052572.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015135620.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015135620", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015135620" } ] }, { "annotation": "Potassium channel subunit. Modulates channel activity by shifting the threshold and the half-maximal activation to more negative values.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCX9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCX9#function" }, { "database": "UniProtKB", "id": "ARBA00056149", "url": "https://www.uniprot.org/uniprotkb/ARBA00056149#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCX9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCX9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "KCNV2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCX9", "locus": { "chromosome": "Z", "start_pos": 27113620, "end_pos": 27107745, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010010198", "url": "https://www.ensembl.org/id/ENSGALG00010010198" } ] } } ], "crossref": [ { "id": "A0A8V0YCX9", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YCX9", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd18425", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18425", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "431642", "url": "https://www.ncbi.nlm.nih.gov/gene/431642", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003131", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003131", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003968", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003968", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003971", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003971", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005821", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005821", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011333", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011333", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027359", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027359", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028325", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028325", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:431642", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:431642", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YQAVAIY", "url": "https://omabrowser.org/oma/group/YQAVAIY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YCX9", "url": "https://www.orthodb.org/?gene=A0A8V0YCX9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11537", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11537", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11537:SF40", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11537:SF40", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00520", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00520", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02214", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02214", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-1296072", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1296072", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_015135620", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015135620", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YCX9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCX9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YCX9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCX9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLQLNMRRQFPFLKHKGREVPSIITQPNMGKDNEGVCLNKQSDFSGTAPLSSQPLLLLGPEGNYNYYVDDEDEEEEEKDQGKWPTGDRFEGENKLSSSIPFSPAFSSGAPARPSTPSVLNINVGGQSYRLTYQAVATYPKTRLGRLATSTDRRCQLGLCDDYAAQVDEYFFDRDPAVFQLVYNFYASGVLRVRDELCPRSFLEELSYWGVRLKYTPRCCRICFEERRDELSEQLKVQRELRSQAEAQENEQLFHHMRYYGPQRWRLWNLMEKPFSSVTAKVMAVASSFFVLISVVALALNTVEEMQQVDRKSGESRPVLEHIETLCIVFFTLEYLLRLVSTPDLRRFASSALNAVDLIAILPLYLQLLLECFTDDDQPRGRGSQHEYDIEKVGRVGKVGQVLRIMRLMRIFRILKLARHSTGLRAFGFTLRQCYQQVGCLLLFIAMGIFAFSAMVYTVEHDVSSTNFTSIPHAWWWAAVSISTVGYGDMCPETHLGRLFAFLCIAFGIILNGMPISILYNKFSDYYSKLKAYEYTALKKERGKVDFTRRAMKKISECCGEGGARSLPQHG", "length": 570, "header": "tr|A0A8V0YCX9-1|A0A8V0YCX9_CHICK Isoform 1 of Potassium voltage-gated channel subfamily V member 2 OS=Gallus gallus OX=9031 GN=KCNV2 PE=3 SV=1 CANONICAL=A0A8V0YCX9-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YCX9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCX9/entry#A0A8V0YCX9-1", "sequence": { "sequence": "MLQLNMRRQFPFLKHKGREVPSIITQPNMGKDNEGVCLNKQSDFSGTAPLSSQPLLLLGPEGNYNYYVDDEDEEEEEKDQGKWPTGDRFEGENKLSSSIPFSPAFSSGAPARPSTPSVLNINVGGQSYRLTYQAVATYPKTRLGRLATSTDRRCQLGLCDDYAAQVDEYFFDRDPAVFQLVYNFYASGVLRVRDELCPRSFLEELSYWGVRLKYTPRCCRICFEERRDELSEQLKVQRELRSQAEAQENEQLFHHMRYYGPQRWRLWNLMEKPFSSVTAKVMAVASSFFVLISVVALALNTVEEMQQVDRKSGESRPVLEHIETLCIVFFTLEYLLRLVSTPDLRRFASSALNAVDLIAILPLYLQLLLECFTDDDQPRGRGSQHEYDIEKVGRVGKVGQVLRIMRLMRIFRILKLARHSTGLRAFGFTLRQCYQQVGCLLLFIAMGIFAFSAMVYTVEHDVSSTNFTSIPHAWWWAAVSISTVGYGDMCPETHLGRLFAFLCIAFGIILNGMPISILYNKFSDYYSKLKAYEYTALKKERGKVDFTRRAMKKISECCGEGGARSLPQHG", "length": 570, "header": "tr|A0A8V0YCX9-1|A0A8V0YCX9_CHICK Isoform 1 of Potassium voltage-gated channel subfamily V member 2 OS=Gallus gallus OX=9031 GN=KCNV2 PE=3 SV=1 CANONICAL=A0A8V0YCX9-1" }, "locus": { "chromosome": "Z", "start_pos": 27113476, "end_pos": 27107918, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010024259.1", "url": "https://www.ensembl.org/id/ENSGALT00010024259.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010013806.1", "url": "https://www.ensembl.org/id/ENSGALP00010013806.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 115, "start_aa": "Thr", "end_pos": 115, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr115", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:431642", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:431642", "resource": "KEGG Pathway" }, { "id": "R-GGA-1296072", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1296072", "resource": "Reactome", "description": "Voltage gated Potassium channels" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZZR6-1", "protein_name": "Potassium voltage-gated channel subfamily V member 2", "gene_name": "Kcnv2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLKQSTERRWSLSYKLWNTSETEDVPNTGSNQHRKSICSMGARTGSQASIAPQWTEGNYNYYIEEDEDCGEEEDWKDDLAEENQKPEGPPAPLDGHTDTPTQLSTLKVNVGGHSYQLECCELANYPKTRLGRLVTSTSRNCQLGLCDDYEAKTDEYFFDRDPAVFQLIYNFYTSGVLLVRDELCPRSFLEELGYWGVRLKYTPRCCRICFEERRDELSEQLKIQRELRAQAQAEEAEELFRDMRFYGPQRQRLWNLMEKPFSSVAAKAMGVASNLFVLISVVALALNTVEEMQHQAEQGTGGGDPRPILEHVEMLCVAFFTLEFLLRLASTPNLRRFARSALNLVDLVAILPFYLQLLLECFTSEDQRHGKGSPREHDLETVGRVGKVGQVLRIMRLMRIFRILKLARHSTGLRAFGFTLRQCYQQVGCLMLFITMGIFSFSAAVYSVEHDVPGTNFTSILHAWWWAAVSISTVGYGDMYPETHLGRLFAFLCIAFGIILNGMPISILYNKFSDYYSKLKAYEYTAIRRERGKVNFMQRATKKMAECLSGSNAQSATRQEN", "length": 561 }, "evidence": [ { "id": "A0A8V0YCX9", "url": "https://omabrowser.org/oma/group/A0A8V0YCX9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E1BII8-1", "protein_name": "Potassium voltage-gated channel subfamily V member 2", "gene_name": "KCNV2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MLKQTERRRSWGQRSWSTTEGEDAAQEVGSQSHRRSICSVGGRSGSQASIPPWIEGNYNYYIEEDEDGEEEEELWKDEPAEEEDRQPGEAAATTERAEGGGADTPLVSTTLNVNVGGHSYHLDYTELACYPKTRLGRLATSTSRSRQLGLCDDYEVQTDEYFFDRDPEVFQLIYNFYSSGVLLVRDELCPRSFLEELGYWGVRLKYTPRCCRICFEERRDDLSEQLKIQRELRAQAQAEEAEELFQDMRFYGAQRRRLWNLMEKPFSSVAAKAIGVASSLFVLISVVALALNTVEEMQQQPERGEGGGNPRPFLEHVETLCMAFFTLEFLLRLASTPDLRRFARSALNLVDLVAILPLYLQLLLECFTSEDQLHVKGSPREHDLETMGRVGKVGQVLRVMRLLRIFRILKLARHSTGLRAFGFTLRQCYQQVGCLMLFITMGILTFAAAVYSVEHDVQGTNFTSIPHAWWWAAVSISTVGYGDMYPETHLGRLFAFLCIAFGIILNGMPISILYNKFSDYYSKLKAYEYTAIRRERGNVEFLQRAGKKIAECLAGSNSQATPRLNS", "length": 566 }, "evidence": [ { "id": "A0A8V0YCX9", "url": "https://omabrowser.org/oma/group/A0A8V0YCX9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1Q6N3-1", "protein_name": "Potassium voltage-gated channel subfamily V member 2", "gene_name": "kcnv2a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLKLKGRRQSLFPNYKLGVTVPAPKDPEDSDLPFGQHNWVKPWNSMQELSKDIYDIYAEYEDDEEDRLFSTPSKLSSPVKNYMLNINVGGKVYQISYRVAAKYPKTRIGRLATYTDHNRKLDLCDDYTVHNNEFFFDRDPDVFHNIFNFYRTGVLWIKDELCPRNFLEEINYWGVRIKNTHRCCRISFEERQDELNEQLKVQRELEAEVETEEHEDLFQDMAFGHTRFLIWNMMEKPFSSIIAKIMAVASSFFVLVSLVAMTLNTVEEMQYITTNGQLSGKTYCEYVETFCIAFFTMEYLLRLVSTPDLTRFGRSVLNAVDLIAILPLYLQMVLESFESHDYWKHGSDIETVGRVGKLGQVLRIMRLMRIFRILKLARHSTGLRAFGFTLRQCYQQVGCLFLFIAMGILTFSAMVYTVEHDVHKTNFTSIPHAWWWAAVSISTVGYGDMFPETHLGRIFAFACISFGIILNGMPISILFNKFSDYYSKLKAYEYTSSIKNRGKVRFVKRAAKRFAECF", "length": 518 }, "evidence": [ { "id": "A0A8V0YCX9", "url": "https://omabrowser.org/oma/group/A0A8V0YCX9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "G3IIK0-1", "protein_name": "Potassium voltage-gated channel subfamily V member 2", "gene_name": "Kcnv2", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MLKQSNERRLSLGYIPWSIPETEEVSNARSKQHRRSICSLGARTGSQASITPPWTEGNYNYYIEEDEDGGEDGEDWKDDLAEEKQPPECPTALLDDHTDTPAQLSTLKVNVGGHSYQLEWCELANYPKTRLGRLVTSTSRSRQLGLCDDYEAQTDEYFFDRDPAVFHLIYNFYISGVLLVRDELCPRSFLEELGYWGVRLKYTPRCCRICFEERRDELSEQLKIQRELRAQAQAEEAEELFRDMRFYGPQRQRLWNLMEKPFSSVAAKAMGVASNLFVLISVVALALNTVEEMQHQAEEGTGGGDPRPILEHVEMLCVAFFTLEFVLRLASTPNLRGFARSALNLVDLVAILPFYLQLLLECFTSEDQREGKDSQREHDLETVGRVGKVGQVLRLMRLMRIFRILKLARHSTGLRAFGFTLRQCYQQVGCLMLFITMGIFSFSAAVYSVEHDVPGTNFTSILHAWWWAAVSISTVGYGDMYPETHLGRLFAFLCIAFGIILNGMPISILYNKFSDYYSKLKAYEYTAIRRERGKVNFMQRATKKMAQCLSGSNTQPTIRQEN", "length": 562 }, "evidence": [ { "id": "A0A8V0YCX9", "url": "https://omabrowser.org/oma/group/A0A8V0YCX9/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q8CFS6-1", "protein_name": "Potassium voltage-gated channel subfamily V member 2", "gene_name": "Kcnv2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLKQSNERRWSLSYKPWSTPETEDVPNTGSNQHRRSICSLGARTGSQASIAPQWTEGNYNYYIEEDEDCGEEGEDWKDDLAEENQKAECLTSLLDGHNDTPAQMSTLKVNVGGHSYLLECCELANYPKTRLGRLATSTTRRGQLGLCDDYEAQTDEYFFDRDPAVFQLIYNFYTSGVLLVRDELCPRSFLEELGYWGVRLKYTPRCCRICFEERRDELSEQLKIQRELRAQAQAEEAEELFRDMRFYGPQRQRLWNLMEKPFSSVAAKAMGVATNLFVLISVVALALNTVEEMQHQAEQGTGGGDPRPILEHVEMLCVAFFTLEFLLRLASTPNLQRFARSALNLVDLVAILPFYLQLLLECFTSEDQRHNKDSPREHDLETVGRVGKVGQVLRIMRLMRIFRILKLARHSTGLRAFGFTLRQCYQQVGCLMLFITMGIFSFSAAVYSVEHDVPGTNFTSILHAWWWAAVSISTVGYGDMYPETHLGRLFAFLCIAFGIILNGMPISILYNKFSDYYSKLKAYEYTAIRRERGKVNFMQRATKKMAECLSESHAQSTTRQEN", "length": 562 }, "evidence": [ { "id": "A0A8V0YCX9", "url": "https://omabrowser.org/oma/group/A0A8V0YCX9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8TDN2-1", "protein_name": "Potassium voltage-gated channel subfamily V member 2", "gene_name": "KCNV2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLKQSERRRSWSYRPWNTTENEGSQHRRSICSLGARSGSQASIHGWTEGNYNYYIEEDEDGEEEDQWKDDLAEEDQQAGEVTTAKPEGPSDPPALLSTLNVNVGGHSYQLDYCELAGFPKTRLGRLATSTSRSRQLSLCDDYEEQTDEYFFDRDPAVFQLVYNFYLSGVLLVLDGLCPRRFLEELGYWGVRLKYTPRCCRICFEERRDELSERLKIQHELRAQAQVEEAEELFRDMRFYGPQRRRLWNLMEKPFSSVAAKAIGVASSTFVLVSVVALALNTVEEMQQHSGQGEGGPDLRPILEHVEMLCMGFFTLEYLLRLASTPDLRRFARSALNLVDLVAILPLYLQLLLECFTGEGHQRGQTVGSVGKVGQVLRVMRLMRIFRILKLARHSTGLRAFGFTLRQCYQQVGCLLLFIAMGIFTFSAAVYSVEHDVPSTNFTTIPHSWWWAAVSISTVGYGDMYPETHLGRFFAFLCIAFGIILNGMPISILYNKFSDYYSKLKAYEYTTIRRERGEVNFMQRARKKIAECLLGSNPQLTPRQEN", "length": 545 }, "evidence": [ { "id": "A0A8V0YCX9", "url": "https://omabrowser.org/oma/group/A0A8V0YCX9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCX9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCX9" } ], "pmid": "" }, { "name": "voltage-gated potassium channel complex", "id": "GO:0008076", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008076", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCX9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCX9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "protein homooligomerization", "id": "GO:0051260", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051260", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCX9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCX9" } ], "pmid": "" }, { "name": "action potential", "id": "GO:0001508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001508", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCX9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCX9" } ], "pmid": "" }, { "name": "potassium ion transmembrane transport", "id": "GO:0071805", "url": 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], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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AT-III inhibits thrombin, matriptase-3/TMPRSS7, as well as factors IXa, Xa and XIa. Its inhibitory activity is greatly enhanced in the presence of heparin.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCY1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCY1#function" }, { "database": "UniProtKB", "id": "ARBA00025088", "url": "https://www.uniprot.org/uniprotkb/ARBA00025088#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCY1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCY1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SERPINC1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCY1", "locus": { "chromosome": "8", "start_pos": 7392139, "end_pos": 7385922, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010011394", "url": "https://www.ensembl.org/id/ENSGALG00010011394" } ] } } ], "crossref": [ { "id": "A0A8V0YCY1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YCY1", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR000215", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000215", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023796", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023796", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036186", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036186", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042178", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042178", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042185", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042185", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YCY1", "url": "https://www.orthodb.org/?gene=A0A8V0YCY1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11461", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11461", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11461:SF53", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11461:SF53", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00079", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00079", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-381426", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-381426", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-8957275", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8957275", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9769733", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9769733", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9769735", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9769735", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9769739", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9769739", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9769743", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9769743", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YCY1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCY1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YCY1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCY1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MHLFMVCLFGLWGMASPAPYAVEDICTAKPRDIPVNPICIYRNPEKKPQESEVLEPGKGRIPEFTNPRVWELSRANSRFAVVFYKHLADSKDNEENIFLSPLSISTAFAMTKLGACGDTLQQLMEVFQFDTISEKTSDQVHFFFAKLNCRLYKKANKSSELISANRLFGEKSLVFNETYQNISEIVYGAKLWPLNFKEKPELSRKIINEWVANKTERRITEVIPEKGIDDLTVLVLVNTIYFKGHWKSQFPAPNTRLDLFHKANGETCNVPIMYQESRFRYAFIQEDKVQVLELPYKGDDITMVLVLPKAGTPLVEVERDLTSDKLQDWIDSMMEVSLTVSFPRFRVEDSFSVKEKLRKMGLEDLFSPENAKLPGIVAGDRTDLYVSEAFHKAFLEVSFVLSQGMFWSLFFTSMKHKRKNVKDCGSNTGCLHEETLKHSASLCFKWVGREEGRAHQMLHNTCVLIPPSLLVGR", "length": 473, "header": "tr|A0A8V0YCY1-1|A0A8V0YCY1_CHICK Isoform 1 of Antithrombin-III OS=Gallus gallus OX=9031 GN=SERPINC1 PE=1 SV=1 CANONICAL=A0A8V0YCY1-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YCY1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCY1/entry#A0A8V0YCY1-1", "sequence": { "sequence": 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"Protein" ] }, { "id": "A0A8V0YCY3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCY3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSLLSAIPAPGAELWEHKVIIVGLDNAGKTTILYQFSMNEVVHTSPTIGSNVEEIVVNNTRFLMWDIGGQESLRSSWNTYYTNTEFVIVVVDSTDRERISVTKEELYKMLAHEDLKKAGLLIFANKQDVKECMTVAEISQFLKLTSIKDHQWHIQACCALTGEGLCQGLEWMMSRLKIR", "length": 179, "header": "tr|A0A8V0YCY3-1|A0A8V0YCY3_CHICK Isoform 1 of ARF like GTPase 5A OS=Gallus gallus OX=9031 GN=ARL5A PE=3 SV=1 CANONICAL=A0A8V0YCY3-1" }, "isoforms": [ { "isoform_ac": "A0A8V0XZT0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCY3/entry#A0A8V0XZT0-1", "sequence": { "sequence": "MNEVVHTSPTIGSNVEEIVVNNTRFLMWDIGGQESLRSSWNTYYTNTEFVIVVVDSTDRERISVTKEELYKMLAHEDLKKAGLLIFANKQDVKECMTVAEISQFLKLTSIKDHQWHIQACCALTGEGLCQGLEWMMSRLKIR", "length": 142, "header": "tr|A0A8V0XZT0-1|A0A8V0XZT0_CHICK Computationally mapped isoform of ARF like GTPase 5A OS=Gallus gallus OX=9031 GN=ARL5A PE=3 SV=1 CANONICAL=A0A8V0YCY3-1" }, 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"MGLLLSRLWRMFGNEEHKLVMVGLDNAGKTTILYQFLMNEVVHTSPTIGSNVEEVVWRNIHFLVWDLGGQQSLRAAWSTYYTNTELVIMVIDSTDRERLAVTREELYRMLQHEDLSKASLLVYANKQDLKGSMSAAEISRQLDLTSIKKHQWHIQACCALTGEGLYQGLEWIVQRIKNK", "length": 179 }, "evidence": [ { "id": "A0A8V0YCY3", "url": "https://omabrowser.org/oma/group/A0A8V0YCY3/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9Y689-1", "protein_name": "ADP-ribosylation factor-like protein 5A", "gene_name": "ARL5A", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGILFTRIWRLFNHQEHKVIIVGLDNAGKTTILYQFSMNEVVHTSPTIGSNVEEIVINNTRFLMWDIGGQESLRSSWNTYYTNTEFVIVVVDSTDRERISVTREELYKMLAHEDLRKAGLLIFANKQDVKECMTVAEISQFLKLTSIKDHQWHIQACCALTGEGLCQGLEWMMSRLKIR", "length": 179 }, "evidence": [ { "id": "A0A8V0YCY3", "url": "https://omabrowser.org/oma/group/A0A8V0YCY3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", 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"https://www.uniprot.org/uniprotkb/A0A8V0YCY3" } ], "pmid": "" }, { "name": "trans-Golgi network", "id": "GO:0005802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005802", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCY3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCY3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "intracellular protein transport", "id": "GO:0006886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCY3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCY3" } ], "pmid": "" }, { "name": "vesicle-mediated transport", "id": "GO:0016192", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016192", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCY3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCY3" } ], "pmid": "" }, { "name": "protein localization to Golgi membrane", "id": "GO:1903292", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903292", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCY3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCY3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 58, "end_pos": 60, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [ { "evidence": [ { "id": "A0A8V0XZT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XZT0#function" }, { "id": "A0A8V0XZT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XZT0" }, { "id": "PIRSR606689-2", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR606689-2" } ], "binding_site_uniprot": 10, "amino_acid": "Pro", "chebi_lig_id": "CHEBI_18420", "ligand": "Mg(2+)", "ligand_label": "", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 10, "end_pos": 10, "start_aa": "Pro", "end_aa": "Pro", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0YCY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCY3#function" }, { "id": "A0A8V0YCY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCY3" }, { "id": "PIRSR606689-2", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR606689-2" } ], "binding_site_uniprot": 30, "amino_acid": "Thr", "chebi_lig_id": "CHEBI_18420", "ligand": "Mg(2+)", "ligand_label": "", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 30, "end_pos": 30, "start_aa": "Thr", "end_aa": "Thr", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0YCY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCY3#function" }, { "id": "A0A8V0YCY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCY3" }, { "id": "PIRSR606689-2", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR606689-2" } ], "binding_site_uniprot": 47, "amino_acid": "Thr", "chebi_lig_id": "CHEBI_18420", "ligand": "Mg(2+)", "ligand_label": "", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 47, "end_pos": 47, "start_aa": "Thr", "end_aa": "Thr", "glycosite_overlap": "" } ], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 58, "end_pos": 60 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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"A0A8V0YCZ2_CHICK", "mass": { "chemical_mass": 97753.0, "monoisotopic_mass": 97753.0 }, "refseq": { "ac": "XP_040555135", "name": "janus kinase and microtubule-interacting protein 1 isoform X5", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040555135" }, "gene_names": [ { "name": "JAKMIP1", "type": "recommended", "evidence": [ { "id": "A0A8V0YCZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCZ2" } ] }, { "name": "JAKMIP1", "type": "synonym", "evidence": [ { "id": "XP_040555135", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040555135" } ] } ], "protein_names": [ { "name": "Janus kinase and microtubule interacting protein 1", "type": "synonym", "evidence": [ { "id": "A0A8V0YCZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCZ2/entry#names_and_taxonomy" } ] }, { "name": "janus kinase and microtubule-interacting protein 1 isoform X5", "type": "synonym", "evidence": [ { "id": "XP_040555135", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040555135" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052535.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040555135", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040555135" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCZ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCZ2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "JAKMIP1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCZ2", "locus": { "chromosome": "4", "start_pos": 78858484, "end_pos": 78987490, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010011399", "url": "https://www.ensembl.org/id/ENSGALG00010011399" } ] } } ], "crossref": [ { "id": "A0A8V0YCZ2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YCZ2", "database": "AlphaFoldDB", "categories": [] }, { "id": "422854", "url": "https://www.ncbi.nlm.nih.gov/gene/422854", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR024836", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024836", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR031994", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031994", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y4H6", "url": "https://www.orthodb.org/?gene=A0A8V0Y4H6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YCY6", "url": "https://www.orthodb.org/?gene=A0A8V0YCY6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YCZ2", "url": "https://www.orthodb.org/?gene=A0A8V0YCZ2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR18935", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR18935", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR18935:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR18935:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF16034", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16034", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_040555135", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040555135", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Y4H6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y4H6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y4H6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y4H6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YCY6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCY6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YCY6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCY6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YCZ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCZ2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YCZ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCZ2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSKKGRTKGDKPDMDIEALQAANEELRTKLTNIQIEFQQEKSKVGKLREKIQEVKQEREQEQHKHTAYVSELKAKLHEEKMKELQSVRELLIRQHEQEVARMVKIKDSEIQRLQSTVNVLRDGAADKVKTTLVSEAKEEARKAFDSERMKLQQEILELKSGKKQLEEALNNIMQADKMKAADLRMAYQSHQDEINRIKRECERDIRRLMDEIKGKDRVILALEKDLGIQAGHTQKLLLQKEALDEQLVQVKEAERYHSSPKRELPAGVGDITELMGSPEQHLDERDVRRFQLKIAELNAMIRKLEDRNTLLADERNELLKRSRETESQLKPLVEKNKRMSKKNDDMMQCIQRMEEKIKNLSRENVELKEKLSAQPVLKRHTSLNDLSSTRDEQEIEFLRLQVKEKQHVIDDLTVERERLLRSKKQKKKILKPQKRHVVETFFGFDEESLDSETSSVTSYNTDKTDRTPATPEEDLEDSTPKEEAELRFCQLTREYQALQRAYALLQEQVGGTLDAEREARTREQLQADLLRCQAKIEDLEKALIEKGQDSKWVEEKQLLIRTNQELLEKIYRMEQEEHQLKNEMQDAKDQNELLEFRVLELEERERRSPAFNLHITTFPENNGSALQLFCQHEGIKDVNISELMKKLDILGDNGNLRNEEQVAIIQAGTVLSLCEKWLKQIEGTEAALTQKMLDLENEKELFSKQKGYLEEELDFRKQALDQAYMKIQELEATLYNALQQDSGRRASESLTEAQREDLRAAVEKVRRQILRQSREFDSQILHERMELLQQAQQRIRELEDKIELQKRQLKEIEEKFLFLFLFFSLAFILWP", "length": 831, "header": "tr|A0A8V0YCZ2-1|A0A8V0YCZ2_CHICK Isoform 1 of Janus kinase and microtubule interacting protein 1 OS=Gallus gallus OX=9031 GN=JAKMIP1 PE=3 SV=1 CANONICAL=A0A8V0YCZ2-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Y4H6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCZ2/entry#A0A8V0Y4H6-1", "sequence": { "sequence": "MSKKGRTKGDKPDMDIEALQAANEELRTKLTNIQIEFQQEKSKVGKLREKIQEVKQEREQEQHKHTAYVSELKAKLHEEKMKELQSVRELLIRQHEQEVARMVKIKDSEIQRLQSTVNVLRDGAADKVKTTLVSEAKEEARKAFDSERMKLQQEILELKSGKKQLEEALNNIMQADKMKAADLRMAYQSHQDEINRIKRECERDIRRLMDEIKGKDRVILALEKDLGIQAGHTQKLLLQKEALDEQLVQVKEAERYHSSPKRELPAGVGDITELMGSPEQHLDERDVRRFQLKIAELNAMIRKLEDRNTLLADERNELLKRSRETESQLKPLVEKNKRMSKKNDDMMQCIQRMEEKIKNLSRENVELKEKLSAQPVLKRHTSLNDLSSTRDEQEIEFLRLQVKEKQHVIDDLTVVICSCLERERLLRSKKQKKKILKPQKRHVVETFFGFDEESLDSETSSVTSYNTDKTDRTPATPEEDLEDSTPKEEAELRFCQLTREYQALQRAYALLQEQVGGTLDAEREARTREQLQADLLRCQAKIEDLEKALIEKGQDSKWVEEKQLLIRTNQELLEKIYRMEQEEHQLKNEMQDAKDQNELLEFRVLELEVRDSLCCKLSNGAEIMFEPKLKFL", "length": 632, "header": "tr|A0A8V0Y4H6-1|A0A8V0Y4H6_CHICK Computationally mapped isoform of Janus kinase and microtubule interacting protein 1 OS=Gallus gallus OX=9031 GN=JAKMIP1 PE=3 SV=1 CANONICAL=A0A8V0YCZ2-1" }, "locus": { "chromosome": "4", "start_pos": 78929782, "end_pos": 78890436, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027261.1", "url": "https://www.ensembl.org/id/ENSGALT00010027261.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015521.1", "url": "https://www.ensembl.org/id/ENSGALP00010015521.1" } ] } }, { "isoform_ac": "A0A8V0YCY6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCZ2/entry#A0A8V0YCY6-1", "sequence": { "sequence": "MSKKGRTKGDKPDMDIEALQAANEELRTKLTNIQIEFQQEKSKVGKLREKIQEVKQEREQEQHKHTAYVSELKAKLHEEKMKELQSVRELLIRQHEQEVARMVKIKDSEIQRLQSTVNVLRDGAADKVKTTLVSEAKEEARKAFDSERMKLQQEILELKSGKKQLEEALNNIMQADKMKAADLRMAYQSHQDEINRIKRECERDIRRLMDEIKGKDRVILALEKDLGIQAGHTQKLLLQKEALDEQLVQVKEAERYHSSPKRELPAGVGDITELMGSPLKRSRETESQLKPLVEKNKRMSKKNDDMMQCIQRMEEKIKNLSRENVELKEKLSAQPVLKRHTSLNDLSSTRDEQEIEFLRLQVKEKQHVIDDLTVERERLLRSKKQKKKILKPQKRHVVETFFGFDEESLDSETSSVTSYNTDKTDRTPATPEEDLEDSTPKEEAELRFCQLTREYQALQRAYALLQEQVGGTLDAEREARTREQLQADLLRCQAKIEDLEKALIEKGQDSKWVEEKQLLIRTNQELLEKIYRMEQEEHQLKNEMQDAKDQNELLEFRVLELEVRDSLCCKLSNGAEIMFEPKLKFL", "length": 586, "header": "tr|A0A8V0YCY6-1|A0A8V0YCZ2_CHICK Computationally mapped isoform of Janus kinase and microtubule interacting protein 1 OS=Gallus gallus OX=9031 GN=JAKMIP1 PE=3 SV=1 CANONICAL=A0A8V0YCZ2-1" }, "locus": { "chromosome": "4", "start_pos": 78929782, "end_pos": 78890436, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027265.1", "url": "https://www.ensembl.org/id/ENSGALT00010027265.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015524.1", "url": "https://www.ensembl.org/id/ENSGALP00010015524.1" } ] } }, { "isoform_ac": "A0A8V0YCZ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCZ2/entry#A0A8V0YCZ2-1", "sequence": { "sequence": "MSKKGRTKGDKPDMDIEALQAANEELRTKLTNIQIEFQQEKSKVGKLREKIQEVKQEREQEQHKHTAYVSELKAKLHEEKMKELQSVRELLIRQHEQEVARMVKIKDSEIQRLQSTVNVLRDGAADKVKTTLVSEAKEEARKAFDSERMKLQQEILELKSGKKQLEEALNNIMQADKMKAADLRMAYQSHQDEINRIKRECERDIRRLMDEIKGKDRVILALEKDLGIQAGHTQKLLLQKEALDEQLVQVKEAERYHSSPKRELPAGVGDITELMGSPEQHLDERDVRRFQLKIAELNAMIRKLEDRNTLLADERNELLKRSRETESQLKPLVEKNKRMSKKNDDMMQCIQRMEEKIKNLSRENVELKEKLSAQPVLKRHTSLNDLSSTRDEQEIEFLRLQVKEKQHVIDDLTVERERLLRSKKQKKKILKPQKRHVVETFFGFDEESLDSETSSVTSYNTDKTDRTPATPEEDLEDSTPKEEAELRFCQLTREYQALQRAYALLQEQVGGTLDAEREARTREQLQADLLRCQAKIEDLEKALIEKGQDSKWVEEKQLLIRTNQELLEKIYRMEQEEHQLKNEMQDAKDQNELLEFRVLELEERERRSPAFNLHITTFPENNGSALQLFCQHEGIKDVNISELMKKLDILGDNGNLRNEEQVAIIQAGTVLSLCEKWLKQIEGTEAALTQKMLDLENEKELFSKQKGYLEEELDFRKQALDQAYMKIQELEATLYNALQQDSGRRASESLTEAQREDLRAAVEKVRRQILRQSREFDSQILHERMELLQQAQQRIRELEDKIELQKRQLKEIEEKFLFLFLFFSLAFILWP", "length": 831, "header": "tr|A0A8V0YCZ2-1|A0A8V0YCZ2_CHICK Isoform 1 of Janus kinase and microtubule interacting protein 1 OS=Gallus gallus OX=9031 GN=JAKMIP1 PE=3 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"class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YD01-1", "uniprot_ac": "A0A8V0YD01", "uniprot_id": "A0A8V0YD01_CHICK", "mass": { "chemical_mass": 292145.0, "monoisotopic_mass": 292145.0 }, "refseq": { "ac": "XP_004949102", "name": "ectopic P granules protein 5 homolog", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004949102" }, "gene_names": [ { "name": "EPG5", "type": "recommended", "evidence": [ { "id": "A0A8V0YD01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD01" } ] }, { "name": "EPG5", "type": "synonym", "evidence": [ { "id": "XP_004949102", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004949102" } ] } ], "protein_names": [ { "name": "Ectopic P granules protein 5 homolog", "type": "recommended", "evidence": [ { "id": "A0A8V0YD01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD01/entry#names_and_taxonomy" } ] }, { "name": "ectopic P granules protein 5 homolog", "type": "synonym", "evidence": [ { "id": "XP_004949102", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004949102" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052572.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_004949102.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004949102", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004949102" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YD01", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD01" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "EPG5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD01", "locus": { "chromosome": "Z", "start_pos": 2559258, "end_pos": 2509584, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012119", "url": "https://www.ensembl.org/id/ENSGALG00010012119" } ] } } ], "crossref": [ { "id": "416379", "url": "https://www.ncbi.nlm.nih.gov/gene/416379", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR051436", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051436", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR058750", "url": "https://www.ebi.ac.uk/interpro/entry/IPR058750", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR059021", "url": "https://www.ebi.ac.uk/interpro/entry/IPR059021", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR059030", "url": "https://www.ebi.ac.uk/interpro/entry/IPR059030", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:416379", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416379", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "LYCYEAE", "url": "https://omabrowser.org/oma/group/LYCYEAE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YD01", "url": "https://www.orthodb.org/?gene=A0A8V0YD01", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YL70", "url": "https://www.orthodb.org/?gene=A0A8V0YL70", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31139", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31139", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31139:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31139:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF26103", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF26103", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF26106", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF26106", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF26573", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF26573", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF27737", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF27737", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF27745", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF27745", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_004949102", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004949102", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YD01", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD01", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YD01-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD01-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YL70", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL70", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YL70-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL70-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAEAVRTSRKGRPKAKAKEKKKRSNEDSQIQEPDDVFLPPVAEVSSQATKVQVEQPGEFTEIQLSDETEHGKAVTDSCDISLSNLTLGSQGSLTAAVEPSADGEESKAGPSHEECRGDVEKSERSKLDKPPSLAEVVASGSGKSDLLGSSFHSSATASQAVVGIARGKDTENVQDAKSPLVRFSEKPPLSPSQPCEKSRTRVHHLGMKSVYPDLSTELSYERPTIMAVKPLLHNERLYPELPTEPELVPFTREQLKVFEPCSWLENVDSYTEEFESVAHQDRHEFYELLLNYMRCRKQLLLAEAELQAMTTDCQNIKGRLWTFKEEQKTVQGVCADQCKVTGHHRYQTVEMNGSVLGELKKLFEAKAEHVHQTLSLHSYTSVLSRLQVESYVYRLLNSSSLLRSVALQQQEQVSKQSENLSSDLSHLKECISVLFSFTRRVIEDPQFQSDLLMWLQRLVSVLQRIGCPGDHLFLFNHILRCPAGIGEWAVPFIQIKVLDNPSGVFHFMQSLALLMSPVKNRVDFMCHMKPNERKSSSSSGKESGNWTLVDEGGEEDEDPETSWILLLEDDLIALLSQFPFHELFQHFLGFKSAGTYFPEKTTSQEMMKIFAFANSLVELLSVGLETFNRARYRQFVKRIGQLIKMTLCHVSDHWAQYISGNKQYGSIGHPYSMDKLQLEFDELFFRAVLHVLKAKRLGVWLFMSEMPYGTLSSSMLWKLFFVMHCAESENLEKLCSTLQPADCKQRLEDPKHLESFEKYLQSMNCSEEICLLTTFAQMAQTKRADVDEDFIRIIVLEIYEVSYVSLSTRETFSKVGRELLGAIASVHTQIISVLLDRVRETIEKVGMVSLYLFKELPLYLWKPSSSEIALIREWLLNYSLTTVENKLACIILEGLNWGLGEQKNALHLDPAVHSEVALMVLEAYLKYLSQKPYAGLLSESIKQVSYLASIVRYGETPESSFNQWAWGLILRLKLHRNDRGIQCGWPAVPVSDSVLDMTESITLHPLLKAVKAGIPIGCYLALAMTTLGHSIEKFCAEGIPLLGVLVQSRYLRTVVHVLDKVLPIFYSCQYYLLKSEQFLSHVQLFLQLDSGVPQGMTQQVTHKVTQHLTGASYGENVKLLNSMIQTHIFRSGQPNGVGPTAVLEFWVQVLISQQLWHRDQATLYLLDHLCKAAFQYSQEDCIQKLLYQQHKNALGYHCDKGLLSSLVSWIVAGNVTPSFVEGNANSSQVWFSWMVLNIESIFEEDSQLRRVVEGELIINDLSPDQALKKAQAQLKLPVVPSLQRLMIYRWAHQALATPADHPLMPLIWQKFFLLYLHRPGPQYGLPVDGCIGRRFFQSAALVNLLNEMKQRLTEVADFHHTASKALKVESPVKSSDRSPEKASCLPDYLTSPELHKELVRLCNVFILWLEEESFQKGDTYIPSLPKQYDAHRLAKIMQNQQDLWMEYVNIELIHHEFQEAINLWTRAQLESHTSAAISAGQIDFTNPLSAKERIMNNLKKFDLPKPPLSLQPMKAPVPVISSASLINQKEAIQLTHADLKVLQGHAKTAALWESQHVALNSEILDTIPKLYVNREEQITLHLECRGASNKGCQGAALVTIQFEGKHKNEAVSQQLHALRKEVRQLQAEAMKPPSLGVVEAAVHVENFITTLINIYKVQPMPAIKKVGISLFFILVEYVCDETQRNPPTRQFFTSCIEILGQVFISGTKSECKRLLQTILHNRRLCTLLSPYFTPVASPDEFVALYEKVVTFLSEDNSDVVFMLLTKFDLTQWLNVTRPPLSERTRLLESIHLALSACGLEPEEDILMPFNIFCNHWTNLLQYQFPDHYSDFLRLFVQSSSEQLLSPDCWKAALKALGCGSPVAEQGSFKKSDCTESPVLRDAGEILLSAEQVRETIEWLSTSFCKLRLASVDFRTFGLFSKWSPYVPAVNTFLEYLIKRLIETEVVSLAQEPVGSNGVLAALQSLYSVIAGLFKPWILVLDKEDASNQPCYPWLESDTPAASSMVCLFTDCIKLLHESFKDKLLPSHHGALWLHLMHYCGCCTAPKMPEFILYTFHTEFRRLPWKEMHPDQMLMEEFFKVERGSPKSCFLFLGYVLCEINWVSVLSDAWNPNPHPQTHNMIVCLLYMMVLLAKEEQLIGKEESPLINLLGQTSSLPWQLVGISSYQSIISYCNSHYPPSVVLAKDAASELIVKLLKISAGFGTSSDSHIHLDATLKCQAYIRQVVQFLSTLEQSGKITLAVLEQEMSKLLDDVVIFNPPDMDLQTRHLALSSLFTETLMMLNNSSVTTAESLRGSLRKWIDSKVHGLLAMPLLTAACQSLASVRHMAETTEACITSYFNKDLPHHQDLGWGPVLASLQVPELTMEEFLQECLSLGSYLTLYVYLLQCLNTDQTLTNEMKILITISKWLEQVYPSSAKEEAKLFLWWHKAMQLSLIQMEQDDAIVMESVIRTLLSIQGRQSQLAEERLTSGILGAIGLGRRSPLSPRFRLVARSLSAFLLVQIPAEDQVRLKAGSEPKLTQKAQQALGVLESMASNKQYMDFQDQIAQASLFIKHPEHCLRDGNNLLALLVNTLYPEVHYLDCIR", "length": 2584, "header": "tr|A0A8V0YD01-1|A0A8V0YD01_CHICK Isoform 1 of Ectopic P granules protein 5 homolog OS=Gallus gallus OX=9031 GN=EPG5 PE=3 SV=1 CANONICAL=A0A8V0YD01-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YD01-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD01/entry#A0A8V0YD01-1", "sequence": { "sequence": "MAEAVRTSRKGRPKAKAKEKKKRSNEDSQIQEPDDVFLPPVAEVSSQATKVQVEQPGEFTEIQLSDETEHGKAVTDSCDISLSNLTLGSQGSLTAAVEPSADGEESKAGPSHEECRGDVEKSERSKLDKPPSLAEVVASGSGKSDLLGSSFHSSATASQAVVGIARGKDTENVQDAKSPLVRFSEKPPLSPSQPCEKSRTRVHHLGMKSVYPDLSTELSYERPTIMAVKPLLHNERLYPELPTEPELVPFTREQLKVFEPCSWLENVDSYTEEFESVAHQDRHEFYELLLNYMRCRKQLLLAEAELQAMTTDCQNIKGRLWTFKEEQKTVQGVCADQCKVTGHHRYQTVEMNGSVLGELKKLFEAKAEHVHQTLSLHSYTSVLSRLQVESYVYRLLNSSSLLRSVALQQQEQVSKQSENLSSDLSHLKECISVLFSFTRRVIEDPQFQSDLLMWLQRLVSVLQRIGCPGDHLFLFNHILRCPAGIGEWAVPFIQIKVLDNPSGVFHFMQSLALLMSPVKNRVDFMCHMKPNERKSSSSSGKESGNWTLVDEGGEEDEDPETSWILLLEDDLIALLSQFPFHELFQHFLGFKSAGTYFPEKTTSQEMMKIFAFANSLVELLSVGLETFNRARYRQFVKRIGQLIKMTLCHVSDHWAQYISGNKQYGSIGHPYSMDKLQLEFDELFFRAVLHVLKAKRLGVWLFMSEMPYGTLSSSMLWKLFFVMHCAESENLEKLCSTLQPADCKQRLEDPKHLESFEKYLQSMNCSEEICLLTTFAQMAQTKRADVDEDFIRIIVLEIYEVSYVSLSTRETFSKVGRELLGAIASVHTQIISVLLDRVRETIEKVGMVSLYLFKELPLYLWKPSSSEIALIREWLLNYSLTTVENKLACIILEGLNWGLGEQKNALHLDPAVHSEVALMVLEAYLKYLSQKPYAGLLSESIKQVSYLASIVRYGETPESSFNQWAWGLILRLKLHRNDRGIQCGWPAVPVSDSVLDMTESITLHPLLKAVKAGIPIGCYLALAMTTLGHSIEKFCAEGIPLLGVLVQSRYLRTVVHVLDKVLPIFYSCQYYLLKSEQFLSHVQLFLQLDSGVPQGMTQQVTHKVTQHLTGASYGENVKLLNSMIQTHIFRSGQPNGVGPTAVLEFWVQVLISQQLWHRDQATLYLLDHLCKAAFQYSQEDCIQKLLYQQHKNALGYHCDKGLLSSLVSWIVAGNVTPSFVEGNANSSQVWFSWMVLNIESIFEEDSQLRRVVEGELIINDLSPDQALKKAQAQLKLPVVPSLQRLMIYRWAHQALATPADHPLMPLIWQKFFLLYLHRPGPQYGLPVDGCIGRRFFQSAALVNLLNEMKQRLTEVADFHHTASKALKVESPVKSSDRSPEKASCLPDYLTSPELHKELVRLCNVFILWLEEESFQKGDTYIPSLPKQYDAHRLAKIMQNQQDLWMEYVNIELIHHEFQEAINLWTRAQLESHTSAAISAGQIDFTNPLSAKERIMNNLKKFDLPKPPLSLQPMKAPVPVISSASLINQKEAIQLTHADLKVLQGHAKTAALWESQHVALNSEILDTIPKLYVNREEQITLHLECRGASNKGCQGAALVTIQFEGKHKNEAVSQQLHALRKEVRQLQAEAMKPPSLGVVEAAVHVENFITTLINIYKVQPMPAIKKVGISLFFILVEYVCDETQRNPPTRQFFTSCIEILGQVFISGTKSECKRLLQTILHNRRLCTLLSPYFTPVASPDEFVALYEKVVTFLSEDNSDVVFMLLTKFDLTQWLNVTRPPLSERTRLLESIHLALSACGLEPEEDILMPFNIFCNHWTNLLQYQFPDHYSDFLRLFVQSSSEQLLSPDCWKAALKALGCGSPVAEQGSFKKSDCTESPVLRDAGEILLSAEQVRETIEWLSTSFCKLRLASVDFRTFGLFSKWSPYVPAVNTFLEYLIKRLIETEVVSLAQEPVGSNGVLAALQSLYSVIAGLFKPWILVLDKEDASNQPCYPWLESDTPAASSMVCLFTDCIKLLHESFKDKLLPSHHGALWLHLMHYCGCCTAPKMPEFILYTFHTEFRRLPWKEMHPDQMLMEEFFKVERGSPKSCFLFLGYVLCEINWVSVLSDAWNPNPHPQTHNMIVCLLYMMVLLAKEEQLIGKEESPLINLLGQTSSLPWQLVGISSYQSIISYCNSHYPPSVVLAKDAASELIVKLLKISAGFGTSSDSHIHLDATLKCQAYIRQVVQFLSTLEQSGKITLAVLEQEMSKLLDDVVIFNPPDMDLQTRHLALSSLFTETLMMLNNSSVTTAESLRGSLRKWIDSKVHGLLAMPLLTAACQSLASVRHMAETTEACITSYFNKDLPHHQDLGWGPVLASLQVPELTMEEFLQECLSLGSYLTLYVYLLQCLNTDQTLTNEMKILITISKWLEQVYPSSAKEEAKLFLWWHKAMQLSLIQMEQDDAIVMESVIRTLLSIQGRQSQLAEERLTSGILGAIGLGRRSPLSPRFRLVARSLSAFLLVQIPAEDQVRLKAGSEPKLTQKAQQALGVLESMASNKQYMDFQDQIAQASLFIKHPEHCLRDGNNLLALLVNTLYPEVHYLDCIR", "length": 2584, "header": "tr|A0A8V0YD01-1|A0A8V0YD01_CHICK Isoform 1 of Ectopic P granules protein 5 homolog OS=Gallus gallus OX=9031 GN=EPG5 PE=3 SV=1 CANONICAL=A0A8V0YD01-1" }, "locus": { "chromosome": "Z", "start_pos": 2557511, "end_pos": 2509600, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029058.1", "url": "https://www.ensembl.org/id/ENSGALT00010029058.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016817.1", "url": "https://www.ensembl.org/id/ENSGALP00010016817.1" } ] } }, { "isoform_ac": "A0A8V0YL70-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD01/entry#A0A8V0YL70-1", "sequence": { "sequence": "MAEAVRTSRKGRPKAKAKEKKKRSNEDSQIQEPDDVFLPPVAEVSSQATKVQVEQPGEFTEIQLSDETEHGKAVTDSCDISLSNLTLGSQGSLTAAVEPSADGEESKAGPSHEECRGDVEKSERSKLDKPPSLAEVVASGSGKSDLLGSSFHSSATASQAVVGIARGKDTENVQDAKSPLVRFSEKPPLSPSQPCEKSRTRVHHLGMKSVYPDLSTELSYERPTIMAVKPLLHNERLYPELPTEPELVPFTREQLKVFEPCSWLENVDSYTEEFESVAHQDRHEFYELLLNYMRCRKQLLLAEAELQAMTTDCQNIKGRLWTFKEEQKTVQGVCADQCKVTGHHRYQTVEMNGSVLGELKKLFEAKAEHVHQTLSLHSYTSVLSRLQVESYVYRLLNSSSLLRSVALQQQEQVSKQSENLSSDLSHLKECISVLFSFTRRVIEDPQFQSDLLMWLQRLVSVLQRIGCPGDHLFLFNHILRCPAGIGEWAVPFIQIKVLDNPSGVFHFMQSLALLMSPVKNRVDFMCHMKPNERKSSSSSGKESGNWTLVDEGGEEDEDPETSWILLLEDDLIALLSQFPFHELFQHFLGFKSAGTYFPEKTTSQEMMKIFAFANSLVELLSVGLETFNRARYRQFVKRIGQLIKMTLCHVSDHWAQYISGNKQYGSIGHPYSMDKLQLEFDELFFRAVLHVLKAKRLGVWLFMSEMPYGTLSSSMLWKLFFVMHCAESENLEKLCSTLQPADCKQRLEDPKHLESFEKYLQSMNCSEEICLLTTFAQMAQTKRADVDEDFIRIIVLEIYEVSYVSLSTRETFSKVGRELLGAIASVHTQIISVLLDRVRETIEKVGMVSLYLFKELPLYLWKPSSSEIALIREWLLNYSLTTVENKLACIILEGLNWGLGEQKNALHLDPAVHSEVALMVLEAYLKYLSQKPYAGLLSESIKQVSYLASIVRYGETPESSFNQWAWGLILRLKLHRNDRGIQCGWPAVPVSDSVLDMTESITLHPLLKAVKAGIPIGCYLALAMTTLGHSIEKFCAEGIPLLGVLVQSRYLRTVVHVLDKVLPIFYSCQYYLLKSEQFLSHVQLFLQLDSGVPQGMTQQVTHKVTQHLTGASYGENVKLLNSMIQTHIFRSGQPNGVGPTAVLEFWVQVLISQQLWHRDQATLYLLDHLCKAAFQYSQEDCIQKLLYQQHKVWFSWMVLNIESIFEEDSQLRRVVEGELIINDLSPDQALKKAQAQLKLPVVPSLQRLMIYRWAHQALATPADHPLMPLIWQKFFLLYLHRPGPQYGLPVDGCIGRRFFQSAALVNLLNEMKQRLTEVADFHHTASKALKVESPVKSSDRSPEKASCLPDYLTSPELHKELVRLCNVFILWLEEESFQKGDTYIPSLPKQYDAHRLAKIMQNQQDLWMEYVNIELIHHEFQEAINLWTRAQLESHTSAAISAGQIDFTNPLSAKERIMNNLKKFDLPKPPLSLQPMKAPVPVISSASLINQKEAIQLTHADLKVLQGHAKTAALWESQHVALNSEILDTIPKLYVNREEQITLHLECRGASNKGCQGAALVTIQFEGKHKNEAVSQQLHALRKEVRQLQAEAMKPPSLGVVEAAVHVENFITTLINIYKVQPMPAIKKVGISLFFILVEYVCDETQRNPPTRQFFTSCIEILGQVFISGTKSECKRLLQTILHNRRLCTLLSPYFTPVASPDEFVALYEKVVTFLSEDNSDVVFMLLTKFDLTQWLNVTRPPLSERTRLLESIHLALSACGLEPEEDILMPFNIFCNHWTNLLQYQFPDHYSDFLRLFVQSSSEQLLSPDCWKAALKALGCGSPVAEQGSFKKSDCTESPVLRDAGEILLSAEQVRETIEWLSTSFCKLRLASVDFRTFGLFSKWSPYVPAVNTFLEYLIKRLIETEVVSLAQEPVGSNGVLAALQSLYSVIAGLFKPWILVLDKEDASNQPCYPWLESDTPAASSMVCLFTDCIKLLHESFKDKLLPSHHGALWLHLMHYCGCCTAPKMPEFILYTFHTEFRRLPWKEMHPDQMLMEEFFKVERGSPKSCFLFLGYVLCEINWVSVLSDAWNPNPHPQTHNMIVCLLYMMVLLAKEEQLIGKEESPLINLLGQTSSLPWQLVGISSYQSIISYCNSHYPPSVVLAKDAASELIVKLLKISAGFGTSSDSHIHLDATLKCQAYIRQVVQFLSTLEQSGKITLAVLEQEMSKLLDDVVIFNPPDMDLQTRHLALSSLFTETLMMLNNSSVTTAESLRGSLRKWIDSKVHGLLAMPLLTAACQSLASVRHMAETTEACITSYFNKDLPHHQDLGWGPVLASLQVPELTMEEFLQECLSLGSYLTLYVYLLQCLNTDQTLTNEMKILITISKWLEQVYPSSAKEEAKLFLWWHKAMQLSLIQMEQDDAIVMESVIRTLLSIQGRQSQLAEERLTSGILGAIGLGRRSPLSPRFRLVARSLSAFLLVQIPAEDQVRLKAGSEPKLTQKAQQALGVLESMASNKQYMDFQDQIAQASLFIKHPEHCLRDGNNLLALLVNTLYPEVHYLDCIR", "length": 2547, "header": "tr|A0A8V0YL70-1|A0A8V0YL70_CHICK Computationally mapped isoform of Ectopic P granules protein 5 homolog OS=Gallus gallus OX=9031 GN=EPG5 PE=3 SV=1 CANONICAL=A0A8V0YD01-1" }, "locus": { "chromosome": "Z", "start_pos": 2557511, "end_pos": 2509600, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029060.1", "url": "https://www.ensembl.org/id/ENSGALT00010029060.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016819.1", "url": "https://www.ensembl.org/id/ENSGALP00010016819.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1140, "start_aa": "Thr", "end_pos": 1140, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1140", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1216, "start_aa": "Thr", "end_pos": 1216, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1216", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:416379", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416379", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2JZ84-1", "protein_name": "Ectopic P granules protein 5 homolog", "gene_name": "Epg5", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAEAVKPRRAKAKASRTKGKEKKKHEALQSSDAALLSETCREQGILSPASELKGDGLNVSAASQFHSDVCGWNESEMFDIPLTSLTVVDEGPPIQDTEDLKDRGEVAARDGDDEIELKVDPGDNVRTEGDPGDPSKNFPEVEERTFMQCGSPENTLQSDFPCTQQEGASSQVRESPTRKEDAKALGCSTVLQDVSLHSPYETKEVPQPPRVKKLYPELPAEIAEVPSLVAVKPLLRSERLYPELPSQPELAPFTKEQLKLLEPGSWLENVESYVEEFDNIAHQDRHEFYELLLNYSRCRKQLLLAEAELLTLMSDCQNAKSRLWSFKDEQMAVQGICADQVKVYGHHHYQRVEMNENALGELKKLFDAKSEHLHQTLTLHSYTSVLSRLQVESYIYTLLNSSAVLRSVAVYQADKVSKLTESIPSDVCQLKECISVLFMFTRRVSEDAQFHEDILLWLQKLVSVLQRIGCPGDHFFLLNHILRCPAGISEWAVPFIQIKVLNNPSGVFHFMQSLALLMSPAKNRAEFMCHMKPSEWKPSSSGPASGNWTLVDEGGEEDEDPETSWSLLNEDDLVTLLSQFPFHELFQHLLGFKAKGDYLPETTRPQEMMKIFAFANSLVELLAVGLETFNRARYRQFVKRIGYLIRMTLGYVSDHWAQYVSHNTDVRLTLQPYSMEKLQIEFDELFLRAVLHVLKAKRLGIWLFMSEMPFGTLSVQMLWKLFYLMHQVESGNLQQLCASLQPAECKRQLQDPEHVASFEKCLSSMNSSEEICLLTTFAQMARARRTNVDEGFIKIIVLEIYEVSYVILSTRETFSKVGRELLGSIAAVHPEIISVLLDRVQETIDQVGMVSLYLFKELPLHLWRPSASEIAVIRDWLLSYNLAAVKNKLACVILEGLNWGFAKQGNLHLDQALHTEVALLVLEAYQKYLAQKPYAGLISESMKQVSYLASIVRYGETPETSFNQWAWNLILRLKLHKNDFGRQNFPVVPFCNTVPDMTESSMFHPLLKAVKSGLPIGCYLALAVTAVGHSIEKFCAEGIPLLGVLVQSRHLRAVVHVLDKVLPVFYPCQYYLLKNEQFLSNLLLFLHLDSGVPQGVTQQVTHRVAHHLTGAIHGDNVKLLNSMIQAHICVSTQPDEVGPVAVLEFWVQALISQHLWYREQSILFLMDHLCKTAFQLMQEDCVQKLLYQQHKNALGYHCDRSLLSSLVNWIVAGNITPSFVEGLSTSTQVWFAWTVLNMESIFEEDSQLRRVVERELVINAFSPDQALKKAQVQLKLPIVPSLQRLLIYRWAHQALVTPADHPLLPLIWQKFFLLYLHRPGPQYGLPVDGCIGRRFFQSPSHVNLLKDMKRRLTEVADFHYAASKALRVPAEGSEGTPERQAGTPGFLTSPELHRELVRLFNVYILWLEDENFQKGDIYIPSLPKHYDVYRLAKVMQNQQDLWMEYANMERIQHEFQETVALWTQAKLESHSVPCSSSTQLDFTDPLLAKERVLSNLQRHEAPHPPLVLHPMRPPVPLISSAVLLAQKDATQLMCADLNLLQQQARTATLRESQQVALDGELLEAMPKQYVNREEQATLHLECRGSSGKKCQGAAVVTVQFEGMCKNEAISQQVHVLQKEVWQFQAEAAQPPALNVVEAAVHAENLITALVNTYKLQPTPGVQKVGISLFFTVVDYVSEETQRHPPTRQFFTSCIEILGQVFISGTKSECKKLLQTILKNRRLCSLLSPFFTPNAAPAEFIPLYEKVAKCLSEDNSDLVFMLLTKFDVQQWLSSTKPPLSDRTRLLESIHLALTAWGLEPEEDIMMPFNLFCKHWTHLLLYQFPDQYSDVLRLLVQSSAEQLLSPECWKATLKALGCYAPSIQQGEASVESSVLHSASDVLLSDKQVTETVQWLSDFFYKLRLSKLDFKSFGLFSKWSPYMADVKTFLGYLVKRLTDLELASLAQDPTASSKEVLRSLHSQIIQLFKPWILVLEDTESSHQRHYPWLESDTVVASSLVQLFTDCVSSLHASFKDKLLPGDEGALRLHLLHYTESCTAPRMPEFILYAFHSAYQKLEWKDLHPDQRLMEAFFKVERGSPKSCFLFLGSVLCRVNWVSVLSDAWSPSPLPETQSMVVCLLFMMVLLAKEAQLVDETDSPLLSLLGQTSSLSWHLVDFVSYQSVLGYFSSHYPPSVILAQDCSAELIVRLLKVSAGLSLPADSRKHVDIVPKCQAFTHQMAQFLSALEQDGKVAFPALGQEVSKLLDDIITFNPPDMDSQTRHMALSSLFMEVLMMMNSAAVPTAEYLGVSIRTWIGQKVHGLVVLPLLTAACQSLASVRHMAETTEACITAYFKESSLDQNLGWGPILVSLQVPELTMQEFLQECLALGSCLTLYVYLLQCLNSEQTVKNEMKVLLILSTWLEHVYPSSAQEEAKLLLWWHQALQLSLVQLEQDDSVLTESVIRILLMLQGRQSLMAEERLSSGILGAIGLGRKSPLSNRFRVVARSMAAFLSVQVPAEDQIRLKPSSELHLTPKAQQVLAALESMTLSKQYVEYQDQILHAVQFIRHPGHCLQNGKSFLAFFVNRLYPEVHYLDNIR", "length": 2575 }, "evidence": [ { "id": "A0A8V0YD01", "url": "https://omabrowser.org/oma/group/A0A8V0YD01/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A5WUT8-1", "protein_name": "Ectopic P granules protein 5 homolog", "gene_name": "epg5", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLHLQVKKERQSESVRQPSGSSKAVNEPEFTDVPLSLPHVPPDLNTAASQTSLDHHDKAENEQQHVLLCEKPEVVQKSTCHEDKEHELPSQDAAPRLDQTSVLAPSSQSDPKPLSAKLEPFSVPSIYPSIPASLSQPQLSEDSYSISYELLDGSLMPAASERLVAPAVLTLANQESSPPSLVPVEVVDVERSRERLYPELPKTCQSVKPFTSEQLRMWEPGSWLENVELHEAEFQNLAHQEGHELYELLLSYWRCRKQLTQAQTELQAANSDCKNVQNRLWSFKDERLSLQGICADQNKVYGYHCYQQVTLNEAALAELKHLFSAKAEILHQTVALHSYTSILSRLQVESYLYRLLSSNPTTKSVAVQDTSAGNPKSQPSSLQPLKESISVLFIFTRRVLDDSQFQADIHLWLQRLVSVLHQVGSTGDHLFILNHLLCCPAGVGKWAVPFLQIKVLDNPSGVYHFMQALAILMSPARHRPDFLGHMKPSDARGNNSLTEPASGNWTLVDEGGEEDEDPETSWMLLSEDDLVSLFSQFPFDELFKHLLGICSKGDYQPLATTSQKMMKIFAFASSLVELLAVGLQTYNRARYRQFVKRIGHMIRMTLCYVSDHWAQYISLTGVSRTTVQEQSFSMEKLQVEFDHLFLRAVLHVLKAKRLGIWLFMSEMPYGTLSSSMLWKIFYIMQCAETDGLEKLSCSLSAEDCIQRLRESSHQERFQLWLSEINSSDGICLLTTFAHMAQPRRTDVDPEFVRNIVLEIYEVSYVSVTTREIFSKVGRELLAAIAAAHPHIISVLLERLRETIERVGMVSLYLFKELPLHLWMPAQEEVGLIRDWLMNFSLTAVENRLACIILEGLNWGFQPNGCLILPAPLHSDVALLVIEAYQKYLTDKPYGGILSEGIKQVSYLANVVRLGQTPESSFNQWAWDIVLRLKLHANERSPQDAWCPLPSSSAPSVPEITDSPIMHPVFKAVKAGIPIGCFLAIEMTTIGHSLEKFCSEGISLLKTLIQSRHLRAAVHILENILPLVYNCQFYLLKNEQFLSCVQLFLQLDSGTQGVTQQVTQKVAQHLIGPATCENIKLLNSVIQAHVLESSRNGRVGAVAVLEFWLQVLTEQSLWYRDRAVLFLLDHMCRSAFLHQQEECLQKILYQQHKSALGYHGDKGLLSSIMGWIVAGNVTPSFIEGSSLTGEVWFAWMILNMETMFEEDSQLRRCVEHELLSNPACTPDQALKKAQVRLKLQVVPSLQRLMIYRWAQQALATPADHPILPLVWQKFFQLYLRQPGPEFGLEVKGCIGRRYFHSAAHLSLLKSLRQRLVEVSDFHHAASKALKVPCASGDSGDGLLTPGTPITQYMTSPDLHTEIVRLFTVFALWLDDENLQKQEIYLPSLPKQYDTHRLAKIMQRQQEVWMEHVDIERVQHELQEVLDLWSKVKSEPAVSQNSSSSIFTDFINPLAARERILTHLRKHDAPQGSLLPVPMKAPVPDIPTASLTDEKISTTLIQEDLTKLQHQAKLATVRETQQVALDNELLEVLPQLYINREDQLSMQLECRGKSGQPCQGPANITVKYSSMHKLEPVQNQIQSLKSDIKQLQADGIKAPPQSLAEAAVHTENFITALVNVFKQNPSPGVLKVGITAFYQIVSFVCEDTQRHPPTRQFFTSCIEILGQVFIRDVQSECKHMLKTILLNRRLCNLLSPYFTPNASPSELVSLYEEVVNTLHIDSGDVIFMLLTKFDLFQWLSTTQPPFSERSRLMTVIHQALCTCGLEPEPEVLMPFNIFCKHWTELLLYQFPDHYSDFLRLLMQSSSDQLLSPDCWRTSLKALGCSPQTKNKTNKSRSMLLSPQQVDETIEWLSKYFLKLRLSNGDFRSFGLLSKWGPYIEEVKVFWEDLITYVIDLELNHCGKEPVGSPRLLKALENLHRKMAKLFEPWILVLDTDNTSHPRCSPWLESDAAVAASLVGLYTRLTETLHEKFKDRLLPGQRGALWLHLMFYCETCTSPKMPEYLLYTYHTEYSRLPWKDLHPDQTLMNQFFNVERGSPKSCFVFMGELLCEVNWVSVLSDSLSPQLNPSTHTMVVSVLHLMVFLAKEDLSKPESSVLSLLDQSASLPWNLVDFSSYQNVTRYVSTHYPASLVLSHDTSSQQVVRLLRMAAGFEPTTQVLHHKDMTLKCQAFLHLMVQFLTSLDQNGNISLASLETEMEKLLENIVIFNPPETDLQQRHMATCSLFAEMLTLLNEAGISTAEGLGTKLHCWVEKRARGPLLLPLLTAACRCLASVRHMTRTTEACILSYFTDGCVDQYSGWGPILVSLQVPELTVEDFIQESLSLGSFLTLYVYILQRLNLEQTLLNEKKTLMLLNTWISQVFPSGPADEAKLFLWWHKFLELLQIQVDQEDACSLDTLILTLMAFQNRLVQLGEERLNSGILGAIGLGRKSPLSNRFRVVARSMSAFLLVQVPSENQLRLHPGTELQLSAKAQQALSALEAMASNKQYSELHVSVNQACQFIKYPNHCLRDANTLLTLLVNALYTDLHYLDIIR", "length": 2532 }, "evidence": [ { "id": "A0A8V0YD01", "url": "https://omabrowser.org/oma/group/A0A8V0YD01/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q80TA9-1", "protein_name": "Ectopic P granules protein 5 homolog", "gene_name": "Epg5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAEAVKPRRAKAKASRTKGKEKKKHEALQTCDAGPLPETCREQESPCPASELKGDDLKSSADPQLHSDVCGWNESEMFDIPLTSLTIGDEGPPVQDTEDLKERGEVTAGDGDDEMELKVDPGDNVIAKGEPCKNFPEVEDHTLIQCGPPESTLQPDFPCTQQAVEGSHAREHPTRKQDEAALGCSKVFQNVSLHSSYEAKEVSQPPRVKKLYPELPAEIAEVPALVAVKPLLRSERLYPELPSQPEVTPFTKEQLKLLEPGSWLENVASYVEEFDNIAHQDRHEFYELLLNYSRCRKQLLLAEAELLTLMSDCHSAKSRLWHFKDEQMAVQGICADQVKVYGHHHYQRVEMNENVLGELKKLFDAKSEHLHQTLTLHSYTSVLSRLQVESYIFTLLNSSAALRSLAVYQADQVPKLTESIPSDVCQLKECISVLFMFTRRVSEDAQFHEDILLWLQKLVSVLQRVGCPGDHFFLLNHVLRCPAGIRKWAVPFIQIKVLNNPSGVFHFMQSLALLMSPVKNRAEFMCHMKPSEWKPSSSGPASGNWTLVDEAGEEDEDPETSWILLNEDDLVTLLSQFPFQELFQHLLGFKAKGDYLPETTRPQEMMKIFAFANSLVELLAVGLDTFNRARYRQFVKRIGYLIRMTLGYVSDHWAQYVSHSTGAGLTPQPYSMEKLQVEFDELFLRAVLHVLKAKRLGIWLFMSEMPFGTLSVQMLWKLLYLMHQVESGDLQQLCASLQPAECKRRLQDPEHFASFEKCLSSINSSEEICLLTAFAQMARARRTNVDEDFIKIIVLEIYEVSYVTLSTRETFSKVGRELLGAIAAVHPEIISVLLDRVQETIDQVGMVSLYLFKELPLYLWRPSAPEIAVIRDWLLNNNLTAVKNKLACVILEGLNWGFTEQGTLHLDQALHTEVALLVLEAYQKYLAQKPYTGLISESMKQVSYLASIVRYGETPETSFNQWAWNLILRLKLHKNDFGRQNFPVIPFCSTVPDMTESSMFHPLLKAVKSGLPIGCYLALAVTAVGHSLEKFCAEGIPLLGVLVQSRHLRAVVHALDKILPVFYPYQCYLLKNEQFLSNLLLFLQLDSGVPQGVTQQVTHRVAQHLTGAVHGDNVKLLSSMIQAHICVSTQPDGVGPVAVLEFWVQALISQHLWYREQPILFLMDHLCKTAFHLMQEDCVQKLLYQQHKNALGYHCDRSLLSSLVNWIVAGNITPSFVEGLSTSTQVWFAWTVLNMESIFEEDSQLRRVVERELVINAFSPDQALKKAQVQLKLPIVPSLQRLLIYRWAHQALVTPSDHPLLPLIWQKFFLLYLHRPGPQYGLPVDGCIGRRFFQSPSHVNLLKDMKRRLTEVADFHYAASKALRVPAEGSEGTPEGQAGTPGFLTSPELHRELVRLFNVYVLWLEDENFQKGDTYIPSLPKHYDVHRLAKVMQNQQDLWMEYVNMERIQHEFQETVALWTQAKLESHAAPCSSSAQLDFTDPLLAKARVLSNLEKHEAPHPPLLLHPVRPPVPLIPSAALLTQKDSTQLMCTDLNLLQQQARSATLRESQQVALDGELLETMPKQYVNREDQATLHLECRGSSGKKCQGAAVVTVQFEGMNKNEAVSQQIHVLQKEVRQLQAEAAQPPALNVVEAAVHAENLITALVNTYKLQPTPGVQKLGISLFFTVVDHVSDETQRHPPTRQFFTSCIEILGQVFVSGTKSECRKLLQTILKNRRLCSLLAPFFTPNAAPAEFIQLYERVVTCLREDNSDVIFMLLTKFDIQQWLNSTKPPLSDRTRLLESIHLALTAWGLEPEEDILMPFNLFCKHWTHLLLYQFPDQYSDVLRLLVQSSAEQLLSPECWKATLRALGCYAPSSQQGAASVESSGLHSASRVLLSDKQVMETVQWLSDFFYKLRLSKLDFKSFGLFSKWSPYMADVKTFLGYLVKRLTDLEIASLSQDPTASSKEVLRSLHAQIIQLFKPWILVLEDAESSHQRHYPWLESDTAVASSIVQLFSDCVGSLHTSFKDRLLPGDEGALRLHLLHYCETCTAPKMPEFILYAFHSAYQRLEWKDLHPDQRLMEAFFKVERGSPKSCFLFLGSVLCRVNWVSVLSDAWNPSPLPETQSMAVCLLFMMVLLAKEAQLVDEPDSPLLSLLGQTSSLSWHLVDLVSYQSVLGYFSSHYPPSVVLANDCSSELIVKLLKVSAGLSAHADGRKHVDIVPKCQAFTHQMVQFLSALEQTGKITFPALEREISKLLDDIIIFNPPDMDSQTRHMALSSFFVEVLMMMNNAAVPTAEFLAVSIRTWIGQRVHGLIVLPLLTAACQSLASVRHMAEITEACIMAYFKESSLDQNLGWGPVLVSLQVPQLTARDFLEECLALGSCLTLYVYLLQCLNSEQTVKNDMKMLLVVSGWLEQVYPSSAQEEAKLFLWWHQILQLSLIQLEQNDSVLTESVIRILLMLQSRQSLMAEERLSSGILGAIGLGRRSPLSNRFRVAARSMAAFLLVQVPAEDQIRLKPSSELHLAPKAQQVLTALESMTLSKQYVEYQDQILHALQFIRHPGHCLQNGKSFLALLVNRLYPEVHYLDNIR", "length": 2572 }, "evidence": [ { "id": "A0A8V0YD01", "url": "https://omabrowser.org/oma/group/A0A8V0YD01/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9HCE0-1", "protein_name": "Ectopic P granules protein 5 homolog", "gene_name": "EPG5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAEAVKPQRRAKAKASRTKTKEKKKYETPQREESSEVSLPKTSREQEIPSLACEFKGDHLKVVTDSQLQDDASGQNESEMFDVPLTSLTISNEESLTCNTEPPKEGGEARPCVGDSAVTPKVHPGDNVGTKVETPKNFTEVEENMSVQGGLSESAPQSNFSYTQPAMENIQVRETQNSKEDKQGLVCSSEVPQNVGLQSSCPAKHGFQTPRVKKLYPQLPAEIAGEAPALVAVKPLLRSERLYPELPSQLELVPFTKEQLKILEPGSWLENVESYLEEFDSMAHQDRHEFYELLLNYSRCRKQLLLAEAELLTLTSDCQNAKSRLWQFKEEQMSVQGICADQVKVFSYHRYQRVEMNENALVELKKLFDAKSEHLHQTLALHSYTSVLSRLQVESYIYALLSSSAVLRSSAIHQQGRASKQTESIPSDLCQLKECISVLFMFTRRVNEDTQFHDDILLWLQKLVSVLQRVGCPGDHLFLLNHILRCPAGVSKWAVPFIQIKVLHNPSGVFHFMQSLALLMSPVKNRAEFMCHMKPSERKPSSSGPGSGTWTLVDEGGEEDEDPETSWILLNEDDLVTILAQFPFHELFQHLLGFKAKGDYLPETTRPQEMMKIFAFANSLVELLAVGLETFNRARYRQFVKRIGYMIRMTLGYVSDHWAQYVSHNQGSGLAQQPYSMEKLQVEFDELFLRAVLHVLKAKRLGIWLFMSEMPFGTLSVQMLWKLFYLMHQVESENLQQLSSSLQPAQCKQQLQDPEHFTNFEKCLSSMNSSEEICLLTTFAQMAQARRTNVDEDFIKIIVLEIYEVSYVTLSTRETFSKVGRELLGTITAVHPEIISVLLDRVQETIDQVGMVSLYLFKELPLYLWQPSASEIAVIRDWLLNYNLTVVKNKLACVILEGLNWGFAKQATLHLDQAVHAEVALMVLEAYQKYLAQKPYAGILSESMKQVSYLASIVRYGETPETSFNQWAWNLILRLKLHKNDYGIQPNCPAVPFSVTVPDMTESPTFHPLLKAVKAGMPIGCYLALSMTAVGHSIEKFCAEGIPLLGILVQSRHLRTVVHVLDKILPLFYPCQYYLLKNEQFLSHLLLFLHLDSGVPQGVTQQVTHKVAQHLTGASHGDNVKLLNSMIQAHISVSTQPNEVGPVAVLEFWVQALISQHLWYREQPILFLMDHLCKAAFQLMQEDCIQKLLYQQHKNALGYHCDRSLLSSLVSWIVAGNITPSFVEGLATPTQVWFAWTVLNMESIFEEDSQLRRVIEGELVINSAFTPDQALKKAQTQLKLPIVPSLQRLLIYRWAHQALVTPSDHPLLPLIWQKFFLLYLHRPGPQYGLPIDGCIGRRFFQSPAHINLLKEMKRRLTEVADFHHAASKALRVPAEGSEGLPESHSGTPGYLTSPELHKELVRLFNVYILWLEDENFQKGDTYIPSLPKHYDIHRLAKVMQNQQDLWMEYLNMERIYHEFQETVGLWTQAKLESHSTPCSLSVQLDFTDPLLAKERVLSNLRKHEAPQPPLALHPTKPPVPVISSAVLLSQKDATQLVCTDLNLLQQQARTAALRESQQVALDGELLDTMPKQYVNREEQTTLHLECRGSSGKKCQGAAVVTVQFEGMHKNEAISQQLHVLRKEVKQLQAEAAKPPSLNIVEAAVHAENLITALVNAYKLQPTPGIQKVGISLFFTIVDYVSDETQRHPPTRQFFTSCIEILGQVFISGIKSECRKVLETILKNSRLCSLLSPFFTPNAAPAEFIQLYEQVVKFLSEDNSDMIFMLLTKFDLKQWLSATKPPLSDRTRLLESIHLALTAWGLEPDEDILMPFNLFCKHWTYLLLYQFPDQYSDILRLLMQSSAEQLLSPECWKATLRALGCCAPSCQQGAASTEGAVLPSSSDALLSDKQVMETIQWLSDFFYKLRLSKMDFKSFGLFSKWSPYMADVKTFLGYLVKRLIDLEMTCLAQDPTASRKTVLKSLHSVIIQLFKPWILVLEDNESSQQRHYPWLESDTVVASSIVQLFTDCIDSLHESFKDKLLPGDAGALWLHLMHYCEACTAPKMPEFILYAFHSTYRKLPWKDLHPDQMLMEAFFKVERGSPKSCFLFLGSVLCEVNWVSVLSDAWNSSPHPETRSMIVCLLFMMILLAKEVQLVDQTDSPLLSLLGQTSSLSWHLVDIVSYQSVLSYFSSHYPPSIILAKESYAELIMKLLKVSAGLSIPTDSQKHLDAVPKCQAFTHQMVQFLSTLEQNGKITLAVLEQEMSKLLDDIIVFNPPDMDSQTRHMALSSLFMEVLMMMNNATIPTAEFLRGSIRTWIGQKMHGLVVLPLLTAACQSLASVRHMAETTEACITAYFKESPLNQNSGWGPILVSLQVPELTMEEFLQECLTLGSYLTLYVYLLQCLNSEQTLRNEMKVLLILSKWLEQVYPSSVEEEAKLFLWWHQVLQLSLIQTEQNDSVLTESVIRILLLVQSRQNLVAEERLSSGILGAIGFGRKSPLSNRFRVVARSMAAFLSVQVPMEDQIRLRPGSELHLTPKAQQALNALESMASSKQYVEYQDQILQATQFIRHPGHCLQDGKSFLALLVNCLYPEVHYLDHIR", "length": 2579 }, "evidence": [ { "id": "A0A8V0YD01", "url": "https://omabrowser.org/oma/group/A0A8V0YD01/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VE34-1", "protein_name": "Ectopic P granules protein 5 homolog", "gene_name": "Epg5", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MATLEKPKKEKSKKSRNRVPIEKEEEEPAELSTSEEQRPAENVSLLEEFERVATLASSSSGEAIISHECCISSDVGVTSQEPEGTQEPTETEAQPSAPSAPPSTTVHVVQYPNLQPMQLSNAQVEEHSAKIVYRQAESPTGFALARSHIKLLSTEELRQIYDCPELELAKQFELEFLMNSLLETSEADPLYAAVMEYYELQGKITSNLHDVEKLRKGCAESQKQIWVRQPVTRTFSGTCGDGNVVQECVTYDVIQVDPIKLEVAKTSLTGLYDLVCHAYTNNSITAKITKVKVDQIINDLLTYPNLDGHSVVSLHHTQSGEALQCVSQLRRAISILFSFVRRPSPNANFDKDLKEWLRKLIALQLLLATREDHWFLLFNILRCPNGVGSWAAQFLQLPGTRAVRRGSQQNELPLDLNSPELNHCMAVLQILLMPVKKRNEYLKSQAQAHRELSDTPGATDRWIVVDSDGEDSHTPAGECVGLKESDLVALLNQMPFEKIFTSALRIEKFLDDYIIEPDMITAQQMLAVVVFFSQLVKTIGEGLLTYNNERYKQLAKRLGRLVRHTLQYVFDYNELFINNNLYKSSEMYERIQVELQALLVRACGYIYRTRNLGTWQYFSTLPFGTLDAEVIWHLFYYLNVGFPTDLANDLVSNAEAAFQAEDFWRKFDLANADVAPEDMYYLLQTFFEMANERNRSKDGSLVKAICLHIFHIGYIHKSTREICYKTARDMLANLMDEDLFGCVLVQLKMRYGEVDQAAYLFKALPLENWHPSMDTFEVLSNWLLHFDYQSSESQLARLIISHLNWGLDCEGRLFLPHNIHVRMAHLVNEALNKYAPEVIGASGISESVRQVSSLIDSTQSSREQFTNWCWRMVSVLRLHLMDQGVESVRRTLQHPTEPLLFIPELERMEMIFQGVNENRPLALYVGMLVSLHGHSIPLICQHGFILLQQLLLDHRHAATIRCLELIVPLFLETPETLANCESFQRLITTLLNADRTYLKLAKDMVYANSIGPILELLDNMLHHQIISYTSYGLCSPLNLLNIWLNCFTTLPGWSQNSNLLYLLDRMLRISYQFPDCRAQAVEFFYNYYKDCTEWKSAPKGSALKAFFGGQSVSRIPLISPQNCWLNLVILEIEFRLVDTRIFPELLRQISAQPVEAALKKTISLSKTSAFPASQLVIFKYAQLLASMESTHALFPIVCQKFFELYLWRVPTENESLNFSHNFGVSDKFYEYNVPLMKSIKSQLKSAESYYSALATKNANDDAMAHFYRNCCKLMQNCALWLEDTQINRFTSDAEHLPAQYNSEKLRELLSGHVNHWTEFLCLASLRKEQRHQADQWGRKVMRLSNQKAPRTPVQPKQRQPPAQHIKSLLKSYEKIVENPLHIRVEPIKTPPIDGVIVAQIQKKMTTLNSTANNYHYKTSELNSLDLNYLERVPTLYSMIPYEETRRKECTSLLFKRNCTAPAQIKLTPEHIRINDVISRKQAQNRERHDKIIEDILLAMSVESFAQAIEELGVCIGALLVAPLESSVTQIGVRVFYDIVDNLNEVTMKFQPTHDLYFQVLEKLGVFLEADQAAQGLAILRLALKRPDLLELLAGVFVPSRTDVDHFLSMYEFLIDSHLKHCDTQTLFVLFSKFDLLGWMEAYQPKLSEINRLLLLVLQGLEAWSQPDSSLLQDLFRRHLVHIFGYDFPQHYGEVMQLVLDRTSDQKLMPVVLLDLLNALFVRSNCAELSLQQSEVRVHELALDFARRQKLFTLKAATDTLLLLSRHFQKERLHHGLHGLYPKHKDYCQALVLWFTSFGHTLLASAICSYQELLADQISDIVFGSIVETYSPWLIPYTEETVSGVAHWIRQLTPGQSKVLLPWSEQHVSSCKLMIRSFVATIIQVLQYLPSSNKILEHVFAWYVHHFAQSSTTGHVLAPIHEGLAQLPWERFLPPAQHVELLYDSLQKFLPESHAMLGHIFIRIEWNNWFAQMPQPVSILSRLFTIFVKIAFEPNIHIHPNTSKILEDAIRYPWHLVECSELEQLLKWFVASVEPAIALKIPAESNYADRAVLELLRLACAMLPERSAQDAVVLGTAKRMLYTRSMVRMQRACGAKHQKLLATKEGERAFSNAFLELLDSIDGAISSCSEHRTMEEQRREALNLMLELVAPTQTQSQEVSNIHIKALVWWQQRCSPGNLVMCSTLPAIGHLNTYIASIYSLLEASIENYFRTSPEIASWHAPSWQGLMEALSMSLPKLDLMPIMQGSYFFSLHVFVLYKMEEIATDGDKVTFLQDLSQLLENLKTSPQTEPRMALVWGVIIARGCQIAQVNQQVKKPLHMLARHLQIASTKAEGWGDGLLGVIGLKSEVITNRRKVLTRCLACVIFSLFPANRDLRIPSEEYESALRELSMLLANKKFTDIKPLIVRAVSLLKESTFPDIRAVPHMVCRLISIFYEESYLTTIPEVWDFEFKLMAT", "length": 2455 }, "evidence": [ { "id": "A0A8V0YD01", "url": "https://omabrowser.org/oma/group/A0A8V0YD01/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "autophagosome maturation", "id": "GO:0097352", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097352", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YD01", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD01" } ], "pmid": "" }, { "name": "endosome to lysosome transport", "id": "GO:0008333", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008333", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YD01", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD01" } ], "pmid": "" }, { "name": "cellular response to dsDNA", "id": "GO:1990786", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990786", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YD01", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD01" } ], "pmid": "" }, { "name": "nucleotide transport", "id": "GO:0006862", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006862", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YD01", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD01" } ], "pmid": "" }, { "name": "autophagy", "id": "GO:0006914", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006914", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YD01", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD01" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YD01", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD01" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YD01", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD01" } ], "pmid": "" }, { "name": "lysosome", "id": "GO:0005764", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005764", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YD01", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD01" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1214, "end_pos": 1216, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1225, "end_pos": 1227, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1774, "end_pos": 1776, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2282, "end_pos": 2284, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2283, "end_pos": 2285, "annotation": "n_glycosylation_sequon" }, { "start_pos": 352, "end_pos": 354, "annotation": "n_glycosylation_sequon" }, { "start_pos": 397, "end_pos": 399, "annotation": "n_glycosylation_sequon" }, { "start_pos": 419, "end_pos": 421, "annotation": "n_glycosylation_sequon" }, { "start_pos": 545, "end_pos": 547, "annotation": "n_glycosylation_sequon" }, { "start_pos": 764, "end_pos": 766, "annotation": "n_glycosylation_sequon" }, { "start_pos": 84, "end_pos": 86, "annotation": "n_glycosylation_sequon" }, { "start_pos": 877, "end_pos": 879, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YD01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD01" }, { "id": "PF26106", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF26106" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Epg5-like C-terminal TPR repeats", "eco_id": "ECO_0000259", "start_pos": 2325, "end_pos": 2584, "start_aa": "His", "end_aa": "Arg", "glycosite_overlap": "" }, { "evidence": [ { "id": 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"MREVLRGRSGNRPAPGGQPGPAASMARPWAHTRAALERLERALSCSRCAGVLREPVSLGGCEHVFCLSCMGDHVGKGCPVCHVPAWVQDMQINRQLDDMVQLCGKLRHLLDAGTSDSMESTPTPMCSDFGENSKKGQIKMWFSPRSRKIRCIVNKNQPKTNSNDLCQDPSSVYHFFPSPVHEKPSKPTKKPTQRQSKKMKKKRLADINKAWGLEKPEQKEGVEEKASKEKCVTICNEPVVLCTPEQHSPKETLPQESIQEVDSTKNLVEVEVSPEVKSSQEEDNNKAVCPVQVSKETNCAAEKSPSIESKAMHLKRGREQSKLPGTSQTKRRRSEGSLNRNSDSQTSCSEDLSQDCPIPQVTEPRTPVQVCGSAMKTRSSAASSPLLPKSPSTPSTFKACDQVGIPQSPSVFKSPGSNPIARRNYKGETLLHIASIKGDLAAVEELLKNGADPNVKDNAGWTPLHEACNHGHQEVVELLLQHKALVNSTGYQNDSPLHDAAKNGHVSIVELLLLHGASRDAVPNVNGAQFHLTIWSKSFNPQQHGGFLLLFNLTADRFDNIFGLRPVDYAESEKMKSVLMLPVKNESFSFSQPSESPSQPRDGPLGILGSGLSSKQQKLLNKLATVLKARRCTEFNSTVTHVVVPDVPMPSTVKCMMAVLSGCWVLKFEWVQACLQSTVREQEEKYEIQGGPQRGRLNREQLLPKLFDGCYFYFLGSFNSHQKSDLVELVKAGGGQILVRQPKPDSDVTQTINTVAYHAESTSDQRFCTQYVIYDASSKFKPEKIRQGKVWFAPSSWIVDCIMSFQLLPVK", "length": 811, "header": "tr|A0A8V0YD08-1|A0A8V0YD08_CHICK Isoform 1 of BRCA1 associated RING domain 1 OS=Gallus gallus OX=9031 GN=BARD1 PE=4 SV=1 CANONICAL=A0A8V0YD08-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Y6T3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD08/entry#A0A8V0Y6T3-1", "sequence": { "sequence": "MGDHVGKGCPVCHVPAWVQDMQINRQLDDMVQLCGKLRHLLDAGTSDSMESTPTPMCSDFGENSKKGQIKMWFSPRSRKIRCIVNKNQPKTNSNDLCQDPSSVYHFFPSPVHEKPSKPTKKPTQRQSKKMKKKRLADINKAWGLEKPEQKEGVEEKASKEKCVTICNEPVVLCTPEQHSPKETLPQESIQEVDSTKNLVEVEVSPEVKSSQEEDNNKAVCPVQVSKETNCAAEKSPSIESKAMHLKRGREQSKLPGTSQTKRRRSEGSLNRNSDSQTSCSEDLSQDCPIPQVTEPRTPVQVCGSAMKTRSSAASSPLLPKSPSTPSTFKACDQVGIPQSPSVFKSPGSNPIARRNYKGETLLHIASIKGDLAAVEELLKNGADPNVKDNAGWTPLHEACNHGHQEVVELLLQHKALVNSTGYQNDSPLHDAAKNGHVSIVELLLLHGASRDAVNIFGLRPVDYAESEKMKSVLMLPVKNESFSFSQPSESPSQPRDGPLGILGSGLSSKQQKLLNKLATVLKARRCTEFNSTVTHVVVPDVPMPSTVKCMMAVLSGCWVLKFEWVQACLQSTVREQEEKYEIQGGPQRGRLNREQLLPKLFDGCYFYFLGSFNSHQKSDLVELVKAGGGQILVRQPKPDSDVTQTINTVAYHAESTSDQRFCTQEWEFGPDQLVGTPAALEDF", "length": 683, "header": "tr|A0A8V0Y6T3-1|A0A8V0Y6T3_CHICK Computationally mapped isoform of BRCA1 associated RING domain 1 OS=Gallus gallus OX=9031 GN=BARD1 PE=4 SV=1 CANONICAL=A0A8V0YD08-1" }, "locus": { "chromosome": "7", "start_pos": 4302463, "end_pos": 4262090, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028524.1", "url": "https://www.ensembl.org/id/ENSGALT00010028524.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016372.1", "url": "https://www.ensembl.org/id/ENSGALP00010016372.1" } ] } }, { "isoform_ac": "A0A8V0YBP3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD08/entry#A0A8V0YBP3-1", "sequence": { "sequence": "MGDHVGKGCPVCHVPAWVQDMQINRQLDDMVQLCGKLRHLLDAGTSDSMESTPTPMCSDFGENSKKGQIKMWFSPRSRKIRCIVNKNQPKTNSNDLCQDPSSVYHFFPSPVHEKPSKPTKKPTQRQSKKMKKKRLADINKAWGLEKPEQKEGVEEKASKEKCVTICNEPVVLCTPEQHSPKETLPQESIQEVDSTKNLVEVEVSPEVKSSQEEDNNKAVCPVQVSKETNCAAEKSPSIESKAMHLKRGREQSKLPGTSQTKRRRSEGSLNRNSDSQTSCSEDLSQDCPIPQVTEPRTPVQVCGSAMKTRSSAASSPLLPKSPSTPSTFKACDQVGIPQSPSVFKSPGSNPIARRNYKGETLLHIASIKGDLAAVEELLKNGADPNVKDNAGWTPLHEACNHGHQEVVELLLQHKALVNSTGYQNDSPLHDAAKNGHVSIVELLLLHGASRDAVNIFGLRPVDYAESEKMKSVLMLPVKNESFSFSQPSESPSQPRDGPLGILGSGLSSKQQKLLNKLATVLKARRCTEFNSTVTHVVVPDVPMPSTVKCMMAVLSGCWVLKFEWVQACLQSTVREQEEKYEIQGGPQRGRLNREQLLPKLFDGCYFYFLGSFNSHQKSDLVELVKAGGGQILVRQPKPDSDVTQTINTVAYHAESTSDQRFCTQYVIYDASSKFKPEKIRQGKVWFAPSSWIVDCIMSFQLLPVK", "length": 705, "header": "tr|A0A8V0YBP3-1|A0A8V0YBP3_CHICK Computationally mapped isoform of BRCA1 associated RING domain 1 OS=Gallus gallus OX=9031 GN=BARD1 PE=4 SV=1 CANONICAL=A0A8V0YD08-1" }, "locus": { "chromosome": "7", "start_pos": 4302463, "end_pos": 4264166, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028518.1", "url": "https://www.ensembl.org/id/ENSGALT00010028518.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016366.1", "url": "https://www.ensembl.org/id/ENSGALP00010016366.1" } ] } }, { "isoform_ac": "A0A8V0YBP8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD08/entry#A0A8V0YBP8-1", "sequence": { "sequence": "MACHLAMINMSSPVFVTSSYLLHNSSLSVLREEILCECLVLKRLCASTIDMLGNRFLLLTFRSCMGDHVGKGCPVCHVPAWVQDMQINRQLDDMVQLCGKLRHLLDAGTSDSMESTPTPMCSDFGENSKKGQIKMWFSPRSRKIRCIVNKNQPKTNSNDLCQDPSSVYHFFPSPVHEKPSKPTKKPTQRQSKKMKKKRLADINKAWGLEKPEQKEGVEEKASKEKCVTICNEPVVLCTPEQHSPKETLPQESIQEVDSTKNLVEVEVSPEVKSSQEEDNNKAVCPVQVSKETNCAAEKSPSIESKAMHLKRGREQSKLPGTSQTKRRRSEGSLNRNSDSQTSCSEDLSQDCPIPQVTEPRTPVQVCGSAMKTRSSAASSPLLPKSPSTPSTFKACDQVGIPQSPSVFKSPGSNPIARRNYKGETLLHIASIKGDLAAVEELLKNGADPNVKDNAGWTPLHEACNHGHQEVVELLLQHKALVNSTGYQNDSPLHDAAKNGHVSIVELLLLHGASRDAVNIFGLRPVDYAESEKMKSVLMLPVKNESFSFSQPSESPSQPRDGPLGILGSGLSSKQQKLLNKLATVLKARRCTEFNSTVTHVVVPDVPMPSTVKCMMAVLSGCWVLKFEWVQACLQSTVREQEEKYEIQGGPQRGRLNREQLLPKLFDGCYFYFLGSFNSHQKSDLVELVKAGGGQILVRQPKPDSDVTQTINTVAYHAESTSDQRFCTQYVIYDASSKFKPEKIRQGKVWFAPSSWIVDCIMSFQLLPVK", "length": 769, "header": "tr|A0A8V0YBP8-1|A0A8V0YBP8_CHICK Computationally mapped isoform of BRCA1 associated RING domain 1 OS=Gallus gallus OX=9031 GN=BARD1 PE=4 SV=1 CANONICAL=A0A8V0YD08-1" }, "locus": { "chromosome": "7", "start_pos": 4302655, "end_pos": 4264166, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028523.1", "url": "https://www.ensembl.org/id/ENSGALT00010028523.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016371.1", "url": "https://www.ensembl.org/id/ENSGALP00010016371.1" } ] } }, { "isoform_ac": "A0A8V0YD08-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD08/entry#A0A8V0YD08-1", "sequence": { "sequence": "MREVLRGRSGNRPAPGGQPGPAASMARPWAHTRAALERLERALSCSRCAGVLREPVSLGGCEHVFCLSCMGDHVGKGCPVCHVPAWVQDMQINRQLDDMVQLCGKLRHLLDAGTSDSMESTPTPMCSDFGENSKKGQIKMWFSPRSRKIRCIVNKNQPKTNSNDLCQDPSSVYHFFPSPVHEKPSKPTKKPTQRQSKKMKKKRLADINKAWGLEKPEQKEGVEEKASKEKCVTICNEPVVLCTPEQHSPKETLPQESIQEVDSTKNLVEVEVSPEVKSSQEEDNNKAVCPVQVSKETNCAAEKSPSIESKAMHLKRGREQSKLPGTSQTKRRRSEGSLNRNSDSQTSCSEDLSQDCPIPQVTEPRTPVQVCGSAMKTRSSAASSPLLPKSPSTPSTFKACDQVGIPQSPSVFKSPGSNPIARRNYKGETLLHIASIKGDLAAVEELLKNGADPNVKDNAGWTPLHEACNHGHQEVVELLLQHKALVNSTGYQNDSPLHDAAKNGHVSIVELLLLHGASRDAVPNVNGAQFHLTIWSKSFNPQQHGGFLLLFNLTADRFDNIFGLRPVDYAESEKMKSVLMLPVKNESFSFSQPSESPSQPRDGPLGILGSGLSSKQQKLLNKLATVLKARRCTEFNSTVTHVVVPDVPMPSTVKCMMAVLSGCWVLKFEWVQACLQSTVREQEEKYEIQGGPQRGRLNREQLLPKLFDGCYFYFLGSFNSHQKSDLVELVKAGGGQILVRQPKPDSDVTQTINTVAYHAESTSDQRFCTQYVIYDASSKFKPEKIRQGKVWFAPSSWIVDCIMSFQLLPVK", "length": 811, "header": "tr|A0A8V0YD08-1|A0A8V0YD08_CHICK Isoform 1 of BRCA1 associated RING domain 1 OS=Gallus gallus OX=9031 GN=BARD1 PE=4 SV=1 CANONICAL=A0A8V0YD08-1" }, "locus": { "chromosome": "7", "start_pos": 4306004, "end_pos": 4264166, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028521.1", "url": "https://www.ensembl.org/id/ENSGALT00010028521.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016369.1", "url": "https://www.ensembl.org/id/ENSGALP00010016369.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 393, "start_aa": "Thr", "end_pos": 393, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr393", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "R-GGA-5685938", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5685938", "resource": "Reactome", "description": "HDR through Single Strand Annealing (SSA)" }, { "id": "R-GGA-5685942", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5685942", "resource": "Reactome", "description": "HDR through Homologous Recombination (HRR)" }, { "id": "R-GGA-5689603", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5689603", "resource": "Reactome", "description": "UCH proteinases" }, { "id": "R-GGA-5689901", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5689901", "resource": "Reactome", "description": "Metalloprotease DUBs" }, { "id": "R-GGA-5693537", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5693537", "resource": "Reactome", "description": "Resolution of D-Loop Structures" }, { "id": "R-GGA-5693565", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5693565", "resource": "Reactome", "description": "Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks" }, { "id": "R-GGA-5693568", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5693568", "resource": "Reactome", "description": "Resolution of D-loop Structures through Holliday Junction Intermediates" }, { "id": "R-GGA-5693571", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5693571", "resource": "Reactome", "description": "Nonhomologous End-Joining (NHEJ)" }, { "id": "R-GGA-5693579", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5693579", "resource": "Reactome", "description": "Homologous DNA Pairing and Strand Exchange" }, { "id": "R-GGA-5693607", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5693607", "resource": "Reactome", "description": "Processing of DNA double-strand break ends" }, { "id": "R-GGA-5693616", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5693616", "resource": "Reactome", "description": "Presynaptic phase of homologous DNA pairing and strand exchange" }, { "id": "R-GGA-69473", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-69473", "resource": "Reactome", "description": "G2/M DNA damage checkpoint" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A5G2RET1-1", "protein_name": "BRCA1-associated RING domain protein 1", "gene_name": "BARD1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MPGNRLPRVRSGNEPHPAPSMEPAGRGAWAHSRAALARLEKLLRCSRCTDILREPVCLGGCEHIFCSNCISDCFGSGCPVCYTPAWIQDVKINRQLDSMIQLCSKLRNLLHDADSSDLKEETSRKSLFSDAEYKKNSIKMWFSPRSKKVRYVVSKVSVQTHPPMINDENAQQASLYEFVSTSPPVDVSERAKKASTRCRKKQKKKTLAEINQKWNLEAEKEDGKLDSKEEFKEKLVSFCSQPSVIASPQMNGEIDLLASGSVTESECLGSFTEVSLPLAEHIESPEMESKNEAVTPEKTLCENVLDESKKSLPSRHNGNRGCRSRLTSPVSKRCRNSIPSTSGNSVKQTVLSENVPSPGCSSPPSNKLKRGATLRRKTSNILDESISLSPGTPPSTLNSPSYRRMMSSPSAVKLSPSSLTAVKRNHRGETLLHIASIKGDIPSVEYLLGNGSDPNVKDHAGWTPLHEACNHGHLKVVELLLQHKALVNTTGYQNDSPLHDAVKNGHVDIVKLLLSYGASRNAVNIFGLRPVDYTDSENMKSLLLLPEKDESSSTSHCSAVNTGQRRDGPLVLIGSGLSSEQQKMLSELAAMLKAKKCAEFDSAVTHVVVPGDTVQSTLKCMLGILSGCWILKFEWVKACLQRKKCEQEEKYEIPEGPRRSRLNREQLLPKLFDGCYFYFGGTFKHHPKDNLIKLVTAAGGQILSRKPKPDSDVTQTINTVAYHAKPDSDQRFCTQYIIYEDLSNHRPERVRQGKVWMAPSSWFIDCVMSFELLPLDS", "length": 777 }, "evidence": [ { "id": "A0A8V0YD08", "url": "https://omabrowser.org/oma/group/A0A8V0YD08/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1MAV4-1", "protein_name": "BRCA1-associated RING domain protein 1", "gene_name": "BARD1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MQGNRQPRVRSGNQPHPAPAMKPAGRGAWAHSRAALDRLEKLLRCSRCTNILREPVCLGGCEHIFCSNCVSDCIGSECPVCYTPAWIQDVKINRQLDSMIQLCSKLQNLLHDTDLSDLKEKTSRKSLFNDAQSKKNSIKMWFSPRSKKVRYTVSKLSVQTQPSVKNDENAQQTSMYEFVSPSPPVEVSEGPKKPSTRSRKKQKKKTLAEVNRKWNLEAEKEDGDLDCKGESKEKLVSFCSQPSVIANLQINGEIDLLASGSVTESECLDEVFLPLAEHIESPEIESKNEVVTPEKTVSANYLPSKKSLPSGRNGKRGRHNRISSPVSKRCRSSSQSTGGNSVKQTVLLENMPLLGCSSPPSNKLKVGDTLSRNSRTILDESISLSPGTPPSTLNSPSYRRMMCSPSATKLWPISHTAVKRNHRGETLLHIASIKGDIPSVEYLLQSGSDPNVKDHAGWTPLHEACNHGHLKVVELLLQHKALVNTTGYQNDSPLHDAVKNGHVDIVKLLLTYGASREAVNIFGLRPVDYADSENMKSLLLLPEKKESSSTSHCSVVNTGQRRDGPLVLIGSGLSSEQQKMLSELATILKAKKCAEFDGTVTHVIVPGDTVQSTLKCMLGILSGCWILKFEWVKACLQSKECEQEEKYEIPEGPQKSRLNREQLLPKLFDGCYFYLGGTFKHHPKDNLIKLVAAGGGQILIRKPKPDSDVTQSINTVAYHAKPDSDQRFCTQYIIYEDLSNHRPERVRQGKVWMAPSSWFIDCVMSFELLPLDN", "length": 773 }, "evidence": [ { "id": "A0A8V0YD08", "url": "https://omabrowser.org/oma/group/A0A8V0YD08/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "O70445-1", "protein_name": "BRCA1-associated RING domain protein 1", "gene_name": "Bard1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPRRPPRVCSGNQPAPVPAMEPATDGLWAHSRAALARLEKLLRCSRCANILKEPVCLGGCEHIFCSGCISDCVGSGCPVCYTPAWILDLKINRQLDSMIQLSSKLQNLLHDNKDSKDNTSRASLFGDAERKKNSIKMWFSPRSKKVRYVVTKVSVQTQPQKAKDDKAQEASMYEFVSATPPVAVPKSAKTASRTSAKKHPKKSVAKINREENLRPETKDSRFDSKEELKEEKVVSCSQIPVMERPRVNGEIDLLASGSVVEPECSGSLTEVSLPLAEHIVSPDTVSKNEETPEKKVCVKDLRSGGSNGNRKGCHRPTTSTSDSCGSNIPSTSRGIGEPALLAENVVLVDCSSLPSGQLQVDVTLRRKSNASDDPLSLSPGTPPPLLNNSTHRQMMSSPSTVKLSSGMPARKRNHRGETLLHIASIKGDIPSVEYLLQNGNDPNVKDHAGWTPLHEACSHGHLKVVELLLQHNALVNTPGYQNDSPLHDAVKSGHIDIVKVLLSHGASRNAVNIFGVRPVDYTDNENIRSLLLLPEENESFSTSQCSIVNTGQRKNGPLVFIGSGLSSQQQKMLSKLETVLKAKKCMEFDSTVTHVIVPDEEAQSTLKCMLGILSGCWILKFDWVKACLDSKVREQEEKYEVPGGPQRSRLNREQLLPKLFDGCYFFLGGNFKHHPRDDLLKLIAAAGGKVLSRKPKPDSDVTQTINTVAYHAKPESDQRFCTQYIVYEDLFNCHPERVRQGKVWMAPSTWLISCIMAFELLPLDS", "length": 765 }, "evidence": [ { "id": "A0A8V0YD08", "url": "https://omabrowser.org/oma/group/A0A8V0YD08/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q99728-1", "protein_name": "BRCA1-associated RING domain protein 1", "gene_name": "BARD1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPDNRQPRNRQPRIRSGNEPRSAPAMEPDGRGAWAHSRAALDRLEKLLRCSRCTNILREPVCLGGCEHIFCSNCVSDCIGTGCPVCYTPAWIQDLKINRQLDSMIQLCSKLRNLLHDNELSDLKEDKPRKSLFNDAGNKKNSIKMWFSPRSKKVRYVVSKASVQTQPAIKKDASAQQDSYEFVSPSPPADVSERAKKASARSGKKQKKKTLAEINQKWNLEAEKEDGEFDSKEESKQKLVSFCSQPSVISSPQINGEIDLLASGSLTESECFGSLTEVSLPLAEQIESPDTKSRNEVVTPEKVCKNYLTSKKSLPLENNGKRGHHNRLSSPISKRCRTSILSTSGDFVKQTVPSENIPLPECSSPPSCKRKVGGTSGRKNSNMSDEFISLSPGTPPSTLSSSSYRRVMSSPSAMKLLPNMAVKRNHRGETLLHIASIKGDIPSVEYLLQNGSDPNVKDHAGWTPLHEACNHGHLKVVELLLQHKALVNTTGYQNDSPLHDAAKNGHVDIVKLLLSYGASRNAVNIFGLRPVDYTDDESMKSLLLLPEKNESSSASHCSVMNTGQRRDGPLVLIGSGLSSEQQKMLSELAVILKAKKYTEFDSTVTHVVVPGDAVQSTLKCMLGILNGCWILKFEWVKACLRRKVCEQEEKYEIPEGPRRSRLNREQLLPKLFDGCYFYLWGTFKHHPKDNLIKLVTAGGGQILSRKPKPDSDVTQTINTVAYHARPDSDQRFCTQYIIYEDLCNYHPERVRQGKVWKAPSSWFIDCVMSFELLPLDS", "length": 777 }, "evidence": [ { "id": "A0A8V0YD08", "url": "https://omabrowser.org/oma/group/A0A8V0YD08/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9QZH2-1", "protein_name": "BRCA1-associated RING domain protein 1", "gene_name": "Bard1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPRRPPRVCSGNKPPPVPAMEPATDGLWAHSRAALARLEKLLRCSRCANILREPVCLGGCEHIFCSGCISDCVGSGCPVCHTPAWILDLKINRQLDSMIQLYSKLQNLLHDNKGSDSKDDTSRASLFGDAERKKNSVKMWFSPRSKKIRCVVNKVSVQTQPQKAKDDKAQEASVFEFVSATPPVVVSTRAKTASRTSAKKHPKKSVAKINREGNFRPETRDSRFDSKEKLKEEKVVSFSQTLVMENSRVNGEIDLLASGSVVESVFSGSFAEVSLPLAEHIVSPDTVSKSEEAPEKKVCVEDRCPVGSDGNPKGCHRPPTSTSKKCGSNVPSASGEIREPTLLAENVVLVDCSSLPSGRLQVDVTLRRQSNASDDSLSLSPGTPPSLLNNSTHRQMMSKPSTVKLSSGIPARKRNHRGETLLHIASIKGDISSVEYLLQNGNDPNVKDHAGWTPLHEACSHGHLKIVELLLQHNALVNTTGYHNDSPLHDAAKNGHIDIVKVLLSHGASRNAVNIFGERPVDYTDAENIRSLLLLPEKTDSFSTSQCSVQVNTGQRKSGPLVLIGSGLSSQQQKLLSKLETVLKAKKCAEFDNTVTHVIVPDEEAQSTLKCMLGILNGCWVLKFDWVKACLDSQEREQEEKYEVPGGPQRSRLNREQLLPKLFDGCYFFLGGNFKHHPKEDLLKLIAAAGGRILSRKPKPDSDVTQTINTVAYHAKPDSDQRFCTQYIVYEDLFNCHPERVRQGKVWMAPSTWLISCVMAFELLPLDS", "length": 768 }, "evidence": [ { "id": "A0A8V0YD08", "url": "https://omabrowser.org/oma/group/A0A8V0YD08/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YD08", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD08" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YD08", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD08" } ], "pmid": "" }, { "name": "protein homodimerization activity", "id": "GO:0042803", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042803", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YD08", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD08" } ], "pmid": "" }, { "name": "protein heterodimerization activity", "id": "GO:0046982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046982", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YD08", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD08" } ], "pmid": "" }, { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YD08", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD08" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YD08", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD08" } ], "pmid": "" }, { "name": "nuclear speck", "id": "GO:0016607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016607", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YD08", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD08" } ], "pmid": "" }, { "name": "BRCA1-A complex", "id": "GO:0070531", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070531", "evidence": [ { "database": "UniProtKB", 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Classification", "Other" ] }, { "id": "PF00658", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00658", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-429947", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-429947", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-450408", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-450408", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-72649", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-72649", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-975956", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-975956", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-975957", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-975957", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YD10", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD10", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YD10-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD10-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YD15", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD15", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YD15-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD15-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNPSAPSYPMASLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDMITRRSLGYAYVNFQQPADAERALDTMNFDVIKGKPVRIMWSQRDPSLRKSGVGNIFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDENGSKGYGFVHFETQEAAERAIEKMNGMLLNDRKVFVGRFKSRKEREAELGARAKEFTNVYIKNFGEDMDDERLKELFGKFGPALSVKVMTDESGKSKGFGFVSFERHEDAQKAVDEMNGKELNGKQIYVGRAQKKVERQTELKRKFEQMKQDRITRYQGVNLYVKNLDDGIDDERLRKEFSPFGTITSAKVMMEGGRSKGFGFVCFSSPEEATKAVTEMNGRIVATKPLYVALAQRKEERQAHLTNQYMQRMASVRAVPNPVINPYQPAPPSGYFMAAIPQTQNRAAYYPTNQLAQLARPSPRWTAQGARPHPFQNMPGAIRPAAPRPPFSTMRPASSQVPRVMSTQRVANTSTQTMGPRPAAAATAATPAVRTVPQYKYAAGVRNPQQHLNTQPQVAMQQVSDSVGIVYAELCNVGYLKLQLIISWNLISKWCKINLQPAVHVQGQEPLTASMLASAPPQEQKQMLGERLFPLIQSMHPTLAGKITGMLLEIDNSELLHMLESPESLRSKVDEAVAVLQAHQAKEAAQKAVNNPTGVPSV", "length": 675, "header": "tr|A0A8V0YD15-1|A0A8V0YD15_CHICK Isoform 1 of Polyadenylate-binding protein OS=Gallus gallus OX=9031 GN=PABPC1 PE=1 SV=1 CANONICAL=A0A8V0YD15-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YD10-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD15/entry#A0A8V0YD10-1", "sequence": { "sequence": "MNPSAPSYPMASLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDMITRRSLGYAYVNFQQPADAERALDTMNFDVIKGKPVRIMWSQRDPSLRKSGVGNIFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDENGSKGYGFVHFETQEAAERAIEKMNGMLLNDRKVFVGRFKSRKEREAELGARAKEFTNVYIKNFGEDMDDERLKELFGKFGPALSVKVMTDESGKSKGFGFVSFERHEDAQKAVDEMNGKELNGKQIYVGRAQKKVERQTELKRKFEQMKQDRITRYQGVNLYVKNLDDGIDDERLRKEFSPFGTITSAKVMMEGGRSKGFGFVCFSSPEEATKAVTEMNGRIVATKPLYVALAQRKEERQAHLTNQYMQRMASVRAVPNPVINPYQPAPPSGYFMAAIPQTQNRAAYYPTNQLAQLARPSPRWTAQGARPHPFQNMPGAIRPAAPRPPFSTMRPASSQVPRVMSTQRVANTSTQTMGPRPAAAATAATPAVRTVPQYKYAAGVRNPQQHLNTQPQVAMQQPAVHVQGQEPLTASMLASAPPQEQKQMLGERLFPLIQSMHPTLAGKITGMLLEIDNSELLHMLESPESLRSKVGGLLPSGFHTDLTGAYAGTVE", "length": 629, "header": "tr|A0A8V0YD10-1|A0A8V0YD15_CHICK Computationally mapped isoform of Polyadenylate-binding protein OS=Gallus gallus OX=9031 GN=PABPC1 PE=1 SV=1 CANONICAL=A0A8V0YD15-1" }, "locus": { "chromosome": "2", "start_pos": 128194546, "end_pos": 128182441, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027290.1", "url": "https://www.ensembl.org/id/ENSGALT00010027290.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015544.1", "url": "https://www.ensembl.org/id/ENSGALP00010015544.1" } ] } }, { "isoform_ac": "A0A8V0YD15-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD15/entry#A0A8V0YD15-1", "sequence": { "sequence": "MNPSAPSYPMASLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDMITRRSLGYAYVNFQQPADAERALDTMNFDVIKGKPVRIMWSQRDPSLRKSGVGNIFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDENGSKGYGFVHFETQEAAERAIEKMNGMLLNDRKVFVGRFKSRKEREAELGARAKEFTNVYIKNFGEDMDDERLKELFGKFGPALSVKVMTDESGKSKGFGFVSFERHEDAQKAVDEMNGKELNGKQIYVGRAQKKVERQTELKRKFEQMKQDRITRYQGVNLYVKNLDDGIDDERLRKEFSPFGTITSAKVMMEGGRSKGFGFVCFSSPEEATKAVTEMNGRIVATKPLYVALAQRKEERQAHLTNQYMQRMASVRAVPNPVINPYQPAPPSGYFMAAIPQTQNRAAYYPTNQLAQLARPSPRWTAQGARPHPFQNMPGAIRPAAPRPPFSTMRPASSQVPRVMSTQRVANTSTQTMGPRPAAAATAATPAVRTVPQYKYAAGVRNPQQHLNTQPQVAMQQVSDSVGIVYAELCNVGYLKLQLIISWNLISKWCKINLQPAVHVQGQEPLTASMLASAPPQEQKQMLGERLFPLIQSMHPTLAGKITGMLLEIDNSELLHMLESPESLRSKVDEAVAVLQAHQAKEAAQKAVNNPTGVPSV", "length": 675, "header": "tr|A0A8V0YD15-1|A0A8V0YD15_CHICK Isoform 1 of Polyadenylate-binding protein OS=Gallus gallus OX=9031 GN=PABPC1 PE=1 SV=1 CANONICAL=A0A8V0YD15-1" }, "locus": { "chromosome": "2", "start_pos": 128194546, "end_pos": 128182135, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027294.1", "url": "https://www.ensembl.org/id/ENSGALT00010027294.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015549.1", "url": "https://www.ensembl.org/id/ENSGALP00010015549.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 503, "start_aa": "Thr", "end_pos": 503, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr503", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "R-GGA-429947", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-429947", "resource": "Reactome", "description": "Deadenylation of mRNA" }, { "id": "R-GGA-450408", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-450408", "resource": "Reactome", "description": "AUF1 (hnRNP D0) binds and destabilizes mRNA" }, { "id": "R-GGA-72649", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-72649", "resource": "Reactome", "description": "Translation initiation complex formation" }, { "id": "R-GGA-975956", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-975956", "resource": "Reactome", "description": "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" }, { "id": "R-GGA-975957", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-975957", "resource": "Reactome", "description": "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YD15", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD15" } ], "pmid": "" }, { "name": "mRNA 3'-UTR binding", "id": "GO:0003730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003730", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YD15", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD15" } ], "pmid": "" }, { "name": "poly(A) binding", "id": "GO:0008143", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008143", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YD15", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD15" } ], "pmid": "" }, { "name": "poly(U) RNA binding", "id": "GO:0008266", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008266", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YD15", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD15" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YD15", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD15" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YD15", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD15" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YD15", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD15" } ], "pmid": "" }, { "name": "cytoplasmic stress granule", "id": "GO:0010494", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010494", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YD15", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD15" } ], "pmid": "" }, { "name": "ribonucleoprotein complex", "id": "GO:1990904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990904", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YD15", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD15" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 135, "end_pos": 137, "annotation": "n_glycosylation_sequon" }, { "start_pos": 485, "end_pos": 487, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YD15", 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"snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 135, "end_pos": 137 }, { "start_pos": 485, "end_pos": 487 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", 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"count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YD11-1", "uniprot_ac": "A0A8V0YD11", "uniprot_id": "A0A8V0YD11_CHICK", "mass": { "chemical_mass": 31031.0, "monoisotopic_mass": 31031.0 }, "refseq": {}, "gene_names": [ { "name": "STX12", "type": "recommended", 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Together with SNARE STX6, promotes movement of vesicles from endosomes to the cell membrane, and may therefore function in the endocytic recycling pathway. 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"https://www.uniprot.org/uniprotkb/A0A8V0YD11", "locus": { "chromosome": "23", "start_pos": 1799608, "end_pos": 1787090, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013257", "url": "https://www.ensembl.org/id/ENSGALG00010013257" } ] } } ], "crossref": [ { "id": "A0A8V0YD11", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YD11", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00179", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00179", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd15876", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15876", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000727", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000727", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006011", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006011", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006012", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006012", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR010989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045242", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045242", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YD11", "url": "https://www.orthodb.org/?gene=A0A8V0YD11", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YR83", "url": "https://www.orthodb.org/?gene=A0A8V0YR83", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR19957", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19957", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19957:SF88", "url": 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"sequence": { "sequence": "MSYGPLDPYRPGPTAPPRDFGGIIQTCSANVQRIAQYTAQIKNLMSQLGTKQDSSKLQENLQQLQHSANCLAKETNEYLKELGSLPLPLSASEQRQQRLQKERLMNDFSAALNNFQAVQRQVSEKEKETVARARAGSRISADERFREEQLVSFDSGEDWSQMQSQEEDAAITEQDLELIKERETAIRQLEADILDVNQIFKDLAMMIHDQGDMIGKYSIEANVESAEVHVERASEQLQRAAYYQKKSRKKICILILGLAVASIILGLIIWWTAK", "length": 274, "header": "tr|A0A8V0YD11-1|A0A8V0YD11_CHICK Isoform 1 of Syntaxin-12 OS=Gallus gallus OX=9031 GN=STX12 PE=1 SV=1 CANONICAL=A0A8V0YD11-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YD11-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD11/entry#A0A8V0YD11-1", "sequence": { "sequence": "MSYGPLDPYRPGPTAPPRDFGGIIQTCSANVQRIAQYTAQIKNLMSQLGTKQDSSKLQENLQQLQHSANCLAKETNEYLKELGSLPLPLSASEQRQQRLQKERLMNDFSAALNNFQAVQRQVSEKEKETVARARAGSRISADERFREEQLVSFDSGEDWSQMQSQEEDAAITEQDLELIKERETAIRQLEADILDVNQIFKDLAMMIHDQGDMIGKYSIEANVESAEVHVERASEQLQRAAYYQKKSRKKICILILGLAVASIILGLIIWWTAK", "length": 274, "header": "tr|A0A8V0YD11-1|A0A8V0YD11_CHICK Isoform 1 of Syntaxin-12 OS=Gallus gallus OX=9031 GN=STX12 PE=1 SV=1 CANONICAL=A0A8V0YD11-1" }, "locus": { "chromosome": "23", "start_pos": 1798260, "end_pos": 1787165, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031874.1", "url": "https://www.ensembl.org/id/ENSGALT00010031874.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018677.1", "url": "https://www.ensembl.org/id/ENSGALP00010018677.1" } ] } }, { "isoform_ac": "A0A8V0YR83-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD11/entry#A0A8V0YR83-1", "sequence": { "sequence": "MSYGPLDPYRPGPTAPPRDFGGIIQTCSANVQRIAQYTAQIKNLMSQLGTKQDSSKLQENLQQLQHSANCLAKETNEYLKELGSLPLPLSASEQRQQRLQKERLMNDFSAALNNFQAVQRQVSEKEKETVARARAGSRISADERFREEQLVSFDRLLSIKTFPLIDSPLFVGDGERKGSGEDWSQMQSQEEDAAITEQDLELIKERETAIRQLEADILDVNQIFKDLAMMIHDQGDMIDSIEANVESAEVHVERASEQLQRAAYYQKKSRKKICILILGLAVASIILGLIIWWTAK", "length": 296, "header": "tr|A0A8V0YR83-1|A0A8V0YR83_CHICK Computationally mapped isoform of Syntaxin-12 OS=Gallus gallus OX=9031 GN=STX12 PE=1 SV=1 CANONICAL=A0A8V0YD11-1" }, "locus": { "chromosome": "23", "start_pos": 1798260, "end_pos": 1787165, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031870.1", "url": "https://www.ensembl.org/id/ENSGALT00010031870.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018673.1", "url": "https://www.ensembl.org/id/ENSGALP00010018673.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 14, "start_aa": "Thr", "end_pos": 14, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr14", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], 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"intracellular protein transport", "id": "GO:0006886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YD11", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD11" } ], "pmid": "" }, { "name": "cholesterol efflux", "id": "GO:0033344", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033344", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YD11", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD11" } ], "pmid": "" }, { "name": "protein stabilization", "id": "GO:0050821", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050821", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YD11", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD11" } ], "pmid": "" }, { "name": "vesicle fusion", "id": "GO:0006906", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006906", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YD11", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD11" } ], "pmid": "" }, { "name": "vesicle docking", 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"evidence": [ { "id": "A0A8V0YD11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD11" }, { "id": "PS50192", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50192" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "T-SNARE coiled-coil homology", "eco_id": "ECO_0000259", "start_pos": 176, "end_pos": 218, "start_aa": "Leu", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 14 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { 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"total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YD42-1", "uniprot_ac": "A0A8V0YD42", "uniprot_id": "A0A8V0YD42_CHICK", "mass": { "chemical_mass": 26745.0, "monoisotopic_mass": 26745.0 }, "refseq": { "ac": "XP_040520938", "name": "ribosyldihydronicotinamide dehydrogenase [quinone]", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040520938" }, "gene_names": [ { "name": "NQO2", "type": "recommended", "evidence": [ { "id": "A0A8V0YD42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD42" } ] }, { "name": "NQO2", "type": "synonym", "evidence": [ { "id": "XP_040520938", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040520938" } ] } ], "protein_names": [ { "name": "Ribosyldihydronicotinamide dehydrogenase [quinone]", "type": "recommended", "evidence": [ { "id": "A0A8V0YD42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD42/entry#names_and_taxonomy" } ] }, { "name": "1.10.5.1", "type": "synonym", "evidence": [ { "id": "A0A8V0YD42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD42/entry#names_and_taxonomy" } ] }, { "name": "NRH dehydrogenase [quinone] 2", "type": "synonym", "evidence": [ { "id": "A0A8V0YD42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD42/entry#names_and_taxonomy" } ] }, { "name": "NRH:quinone oxidoreductase 2", "type": "synonym", "evidence": [ { "id": "A0A8V0YD42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD42/entry#names_and_taxonomy" } ] }, { "name": "Quinone reductase 2", "type": "synonym", "evidence": [ { "id": "A0A8V0YD42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD42/entry#names_and_taxonomy" } ] }, { "name": "ribosyldihydronicotinamide dehydrogenase [quinone]", "type": "synonym", "evidence": [ { "id": "XP_040520938", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040520938" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052574.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040520938", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040520938" } ] }, { "annotation": "The enzyme apparently serves as a quinone reductase in connection with conjugation reactions of hydroquinones involved in detoxification pathways as well as in biosynthetic processes such as the vitamin K-dependent gamma-carboxylation of glutamate residues in prothrombin synthesis.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YD42", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD42#function" }, { "database": "UniProtKB", "id": "ARBA00054856", "url": "https://www.uniprot.org/uniprotkb/ARBA00054856#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YD42", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD42" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "NQO2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD42", "locus": { "chromosome": "2", "start_pos": 66095521, "end_pos": 66105972, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010011426", "url": "https://www.ensembl.org/id/ENSGALG00010011426" } ] } } ], "crossref": [ { "id": "A0A8V0YD42", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YD42", "database": "AlphaFoldDB", "categories": [] }, { "id": "420886", "url": "https://www.ncbi.nlm.nih.gov/gene/420886", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003680", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003680", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029039", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029039", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051545", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051545", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:420886", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420886", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "GREHMFG", "url": "https://omabrowser.org/oma/group/GREHMFG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YD42", "url": "https://www.orthodb.org/?gene=A0A8V0YD42", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10204", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10204", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10204:SF33", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10204:SF33", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02525", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02525", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-211945", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-211945", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_040520938", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040520938", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "12364", "url": "https://www.rhea-db.org/rhea/12364", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YD42", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD42", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YD42-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD42-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAGKKVLIVYAHQEPNSFNGSLKTVAVEELSKQGCSVTVSDLYAMQFEPRATRNDIVGCLHNSEEFHYAVEMMEAYKRGCLSNDLTEEQKKVQEADLLIFQFPLYWFSMPAIMKGWMDRVLVQGFAHDYPNCYDSGLLKNKLAMFSFTTGGSEEMYTKESVNGDIRYILWPMQHGIMHFCGVKVLEPHICFAPEYVSEEKRKEMLFAWAQRLKTLWKEEPINCSHEWYFK", "length": 230, "header": "tr|A0A8V0YD42-1|A0A8V0YD42_CHICK Isoform 1 of Ribosyldihydronicotinamide dehydrogenase [quinone] OS=Gallus gallus OX=9031 GN=NQO2 PE=1 SV=1 CANONICAL=A0A8V0YD42-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YD42-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD42/entry#A0A8V0YD42-1", "sequence": { "sequence": "MAGKKVLIVYAHQEPNSFNGSLKTVAVEELSKQGCSVTVSDLYAMQFEPRATRNDIVGCLHNSEEFHYAVEMMEAYKRGCLSNDLTEEQKKVQEADLLIFQFPLYWFSMPAIMKGWMDRVLVQGFAHDYPNCYDSGLLKNKLAMFSFTTGGSEEMYTKESVNGDIRYILWPMQHGIMHFCGVKVLEPHICFAPEYVSEEKRKEMLFAWAQRLKTLWKEEPINCSHEWYFK", "length": 230, "header": "tr|A0A8V0YD42-1|A0A8V0YD42_CHICK Isoform 1 of Ribosyldihydronicotinamide dehydrogenase [quinone] OS=Gallus gallus OX=9031 GN=NQO2 PE=1 SV=1 CANONICAL=A0A8V0YD42-1" }, "locus": { "chromosome": "2", "start_pos": 66105455, "end_pos": 66097644, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027321.1", "url": "https://www.ensembl.org/id/ENSGALT00010027321.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015575.1", "url": "https://www.ensembl.org/id/ENSGALP00010015575.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "gga:420886", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420886", "resource": "KEGG Pathway" }, { "id": "R-GGA-211945", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-211945", "resource": "Reactome", "description": "Phase I - Functionalization of compounds" } ], "orthologs": [ { "uniprot_canonical_ac": "G3IEG3-1", "protein_name": "Ribosyldihydronicotinamide dehydrogenase [quinone]", "gene_name": "Nqo2", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAGKKVLIVYAHQEPMSFNGSLKKVAVEELSKQGCTVTVSDLYAMNFEPRATRNDITGSLSNPEVFRYGIEAYEAYKKTALTSDILEEQKKVQEADLVIFQFPLYWFSVPAILKGWMDRVLCQGFAFDIPGFYDSGLLKGKLALLSLTTGGTAEMYTKTGVSGDFRYFLWPLQHGTLHFCGFKVLAPQISFGIDVSSEEERKVMVASWAKRLKSIWKEEPILCTPPWYFQE", "length": 231 }, "evidence": [ { "id": "A0A8V0YD42", "url": "https://omabrowser.org/oma/group/A0A8V0YD42/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P16083-1", "protein_name": "Ribosyldihydronicotinamide dehydrogenase [quinone]", "gene_name": "NQO2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAGKKVLIVYAHQEPKSFNGSLKNVAVDELSRQGCTVTVSDLYAMNLEPRATDKDITGTLSNPEVFNYGVETHEAYKQRSLASDITDEQKKVREADLVIFQFPLYWFSVPAILKGWMDRVLCQGFAFDIPGFYDSGLLQGKLALLSVTTGGTAEMYTKTGVNGDSRYFLWPLQHGTLHFCGFKVLAPQISFAPEIASEEERKGMVAAWSQRLQTIWKEEPIPCTAHWHFGQ", "length": 231 }, "evidence": [ { "id": "A0A8V0YD42", "url": "https://omabrowser.org/oma/group/A0A8V0YD42/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q6AY80-1", "protein_name": "Ribosyldihydronicotinamide dehydrogenase [quinone]", "gene_name": "Nqo2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAGKKVLLVYAHQEPKSFNGSMKQVAVEELSKQGCTVTVSDLYTMNFEPRATRNDVTGALSNPEVFKYGIEAYEAYKKKALTSDILEEQRKVQEADLVIFQFPLYWFSVPAILKGWMDRVLCQGFAFDVPGFYDSGFLKDKLALLSFTTGGTAEMYTKAGVNGDFRYFLWPLQHGTLHFCGFKVLAPQISFGPEVSSEEQRKVMLASWVQRLKSIWKEEPIHCTPSWYFQG", "length": 231 }, "evidence": [ { "id": "A0A8V0YD42", "url": "https://omabrowser.org/oma/group/A0A8V0YD42/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9JI75-1", "protein_name": "Ribosyldihydronicotinamide dehydrogenase [quinone]", "gene_name": "Nqo2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAGKKVLIVYAHQEPKSFNGSLKKVAVEELSKQGCTVTVSDLYSMNFEPRATRNDITGAPSNPDVFSYGIETHEAYKKKALTSDIFEEQRKVQEADLVIFQFPLYWFSVPAILKGWMDRVLCRGFAFDIPGFYDSGFLKGKLALLSLTTGGTAEMYTKDGVSGDFRYFLWPLQHGTLHFCGFKVLAPQISFGLDVSSEEERKVMLASWAQRLKSIWKEEPIHCTPPWYFQE", "length": 231 }, "evidence": [ { "id": "A0A8V0YD42", "url": "https://omabrowser.org/oma/group/A0A8V0YD42/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YD42", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD42" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 10, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YD42", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD42" } ], "pmid": "" }, { "name": "electron transfer activity", "id": "GO:0009055", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009055", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YD42", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD42" } ], "pmid": "" }, { "name": "protein homodimerization activity", "id": "GO:0042803", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042803", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YD42", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD42" } ], "pmid": "" }, { "name": "FAD binding", "id": "GO:0071949", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071949", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YD42", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD42" } ], "pmid": "" }, { "name": "chloride ion binding", "id": "GO:0031404", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031404", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YD42", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD42" } ], "pmid": "" }, { "name": "NAD(P)H dehydrogenase (quinone) activity", "id": "GO:0003955", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003955", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YD42", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD42" } ], "pmid": "" }, { "name": "dihydronicotinamide riboside quinone reductase activity", "id": "GO:0001512", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001512", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YD42", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD42" } ], "pmid": "" }, { "name": "oxidoreductase activity, acting on other nitrogenous compounds as donors", "id": "GO:0016661", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016661", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YD42", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD42" } ], "pmid": "" }, { "name": "melatonin binding", "id": "GO:1904408", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904408", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YD42", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD42" } ], "pmid": "" }, { "name": "resveratrol binding", "id": "GO:1905594", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905594", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YD42", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD42" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "quinone catabolic process", "id": "GO:1901662", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901662", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YD42", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD42" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 19, "end_pos": 21, "annotation": "n_glycosylation_sequon" }, { "start_pos": 222, "end_pos": 224, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "12364", "name": "", "equation": "1-(beta-D-ribofuranosyl)-1,4-dihydronicotinamide + a quinone + H(+) = beta-nicotinamide D-riboside + a quinol", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YD42-1" ], "evidence": [ { "id": "12364", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/12364" } ] }, { "id": "R-GGA-8936519", "name": "NQO2:FAD dimer reduces quinones to hydroquinones", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [ "R-ALL-8936516", "R-ALL-8936520" ], "output_participant_list": [ "R-ALL-8936507", "R-ALL-8936514" ], "enzyme_list": [ "A0A8V0YD42-1" ], "evidence": [ { "id": "R-GGA-8936519", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8936519" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-8936507", "participant_name": "hydroquinone [cytosol]", "crossref": [ { "id": "17594", "database": "ChEBI", "url": "" }, { "id": "ZINC000005133378", "database": "ZINC", "url": "" }, { "id": "HMDB0002434", "database": "HMDB Metabolite", "url": "" }, { "id": "C00530", "database": "COMPOUND", "url": "" } ] }, { "participant_id": "R-ALL-8936514", "participant_name": "RFNA [cytosol]", "crossref": [ { "id": "ZINC000004096036", "database": "ZINC", "url": "" }, { "id": "15927", "database": "ChEBI", "url": "" }, { "id": "C03150", "database": "COMPOUND", "url": "" }, { "id": "HMDB0000855", "database": "HMDB Metabolite", "url": "" } ] }, { "participant_id": "R-ALL-8936516", "participant_name": "RFDHN [cytosol]", "crossref": [ { "id": "55458", "database": "ChEBI", "url": "" }, { "id": "C15497", "database": "COMPOUND", "url": "" }, { "id": "ZINC000013548506", "database": "ZINC", "url": "" }, { "id": "HMDB0011648", "database": "HMDB Metabolite", "url": "" }, { "id": "HMDB0011643", "database": "HMDB Metabolite", "url": "" } ] }, { "participant_id": "R-ALL-8936520", "participant_name": "quinone [cytosol]", "crossref": [ { "id": "36141", "database": "ChEBI", "url": "" }, { "id": "C15602", "database": "KEGG Gene", "url": "" }, { "id": "Quinones", "database": "AraCyc", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A0A8V0YD42", "gene_name": "NQO2", "activity": [ { "ec_number": "1.10.5.1", "activity": "1-(beta-D-ribofuranosyl)-1,4-dihydronicotinamide + a quinone + H(+) = beta-nicotinamide D-riboside + a quinol.", "evidence": [ { "id": "A0A8V0YD42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD42" } ] }, { "ec_number": "1.10.5.1", "activity": "", "evidence": [ { "id": "A0A8V0YD42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD42" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YD42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD42" }, { "id": "PF02525", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02525" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Flavodoxin-like fold", "eco_id": "ECO_0000259", "start_pos": 4, "end_pos": 211, "start_aa": "Lys", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "1.10.5.1", "ec_name": "1-(beta-D-ribofuranosyl)-1,4-dihydronicotinamide + a quinone + H(+) = beta-nicotinamide D-riboside + a quinol.", "evidence": [ { "id": "1.10.5.1", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:1.10.5.1" }, { "id": "1.10.5.1", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=1.10.5.1" } ] } ], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 19, "end_pos": 21 }, { "start_pos": 222, "end_pos": 224 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YD47-1", "uniprot_ac": "A0A8V0YD47", "uniprot_id": "A0A8V0YD47_CHICK", "mass": { "chemical_mass": 35997.0, "monoisotopic_mass": 35997.0 }, "refseq": {}, "gene_names": [ { "name": "CCDC53", "type": "recommended", "evidence": [ { "id": "A0A8V0YD47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD47" } ] } ], "protein_names": [ { "name": "WASH complex subunit 3", "type": "recommended", "evidence": [ { "id": "A0A8V0YD47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD47/entry#names_and_taxonomy" } ] }, { "name": "Coiled-coil domain-containing protein 53", "type": "synonym", "evidence": [ { "id": "A0A8V0YD47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD47/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YD47", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD47" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CCDC53", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD47", "locus": {} } ], "crossref": [ { "id": "A0A8V0YD47", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YD47", "database": "AlphaFoldDB", "categories": [] }, { "id": "418094", "url": "https://www.ncbi.nlm.nih.gov/gene/418094", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR019309", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019309", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y4M2", "url": "https://www.orthodb.org/?gene=A0A8V0Y4M2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y4N1", "url": "https://www.orthodb.org/?gene=A0A8V0Y4N1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y9C3", "url": "https://www.orthodb.org/?gene=A0A8V0Y9C3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YAV8", "url": "https://www.orthodb.org/?gene=A0A8V0YAV8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YAW4", "url": "https://www.orthodb.org/?gene=A0A8V0YAW4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YD47", "url": "https://www.orthodb.org/?gene=A0A8V0YD47", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YHS8", "url": "https://www.orthodb.org/?gene=A0A8V0YHS8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YHT3", "url": "https://www.orthodb.org/?gene=A0A8V0YHT3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13015", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13015", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13015:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13015:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10152", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10152", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0Y4M2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y4M2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y4M2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y4M2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y4N1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y4N1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y4N1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y4N1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y9C3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9C3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y9C3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9C3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YAV8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAV8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YAV8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAV8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YAW4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAW4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YAW4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAW4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YD47", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD47", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YD47-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD47-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHS8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHS8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHS8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHS8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHT3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHT3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHT3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHT3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MISKVPSNPNHSMIHSMILVDFSDRNDSLVKLPKWKKRNINPSAAPGPGAEERRRGTRSAAHAYSPSSLTNYTFHGAPHGQRTCADKPAPSCRAGRGVLFPGRGRLRTRGASGVRAVYRPAGMDEDGLPIVGSGIDLTKVPAIQQKRTVAFLNQFVVHTVQFLNRFSTVCEEKLSALSLRIQQIETTLNILDAKLSSIPGLEDVKFEVSSANLNSVTSSPMAPATTDQQAAVSPQSGQNNKHEEALQKTEIVTENMRTVAKDPRYARYLKMVQVGVPVMAIRNKMISEGLNPDLLEAFFWNIVQADVLLNRRPLVFCQFPDMLKYF", "length": 326, "header": "tr|A0A8V0YD47-1|A0A8V0YD47_CHICK Isoform 1 of WASH complex subunit 3 OS=Gallus gallus OX=9031 GN=CCDC53 PE=1 SV=1 CANONICAL=A0A8V0YD47-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Y4M2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD47/entry#A0A8V0Y4M2-1", "sequence": { "sequence": "MDEDGLPIVGSGIDLTKVPAIQQKRTVAFLNQFVVHTVQFLNRFSTVCEEKLSALSLRIQQIETTLNILDAKLSSIPGLEDVKFEVSSANLNSVTSSPMAPATTDQQAAVSPQSGNNKHEEALQKTEIVTENMRTVAKDPRYARYLKMVQVDSRCPCACLGR", "length": 162, "header": "tr|A0A8V0Y4M2-1|A0A8V0Y4M2_CHICK Computationally mapped isoform of WASH complex subunit 3 OS=Gallus gallus OX=9031 GN=CCDC53 PE=3 SV=1 CANONICAL=A0A8V0YD47-1" }, "locus": { "chromosome": "1", "start_pos": 55509058, "end_pos": 55495482, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027313.1", "url": "https://www.ensembl.org/id/ENSGALT00010027313.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015567.1", "url": "https://www.ensembl.org/id/ENSGALP00010015567.1" } ] } }, { "isoform_ac": "A0A8V0Y4N1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD47/entry#A0A8V0Y4N1-1", "sequence": { "sequence": "MDEDGLPIVGSGIDLTKVPAIQQKRTVAFLNQFVVHTVQFLNRFSTVCEEKLSALSLRIQQIETTLNILDAKLSSIPGLEDVKFEVSSANLNSVTSSPMAPATTDQQAAVSPQSGQNNKHEEALQKTEIVTENMRTVAKDPRYARYLKMVQPPAILALQMLSWPVVVGERERILKIEVSEDLM", "length": 183, "header": "tr|A0A8V0Y4N1-1|A0A8V0Y4N1_CHICK Computationally mapped isoform of WASH complex subunit 3 OS=Gallus gallus OX=9031 GN=CCDC53 PE=3 SV=1 CANONICAL=A0A8V0YD47-1" }, "locus": { "chromosome": "1", "start_pos": 55515019, "end_pos": 55495482, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027323.1", "url": "https://www.ensembl.org/id/ENSGALT00010027323.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015577.1", "url": "https://www.ensembl.org/id/ENSGALP00010015577.1" } ] } }, { "isoform_ac": "A0A8V0Y9C3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD47/entry#A0A8V0Y9C3-1", "sequence": { "sequence": "MDEDGLPIVGSGIDLTKVPAIQQKRTVAFLNQFVVHTVQFLNRFSTVCEEKLSALSLRIQQIETTLNILDAKLSSIPGLEDVKFEVSSANLNSVTSSPMAPATTDQQAAVSPQSGQNNKHEEALQKTEIVTENMRTVAKDPRYARYLKMVQVGVPVMAIRNKMISEGLNPDLLERFCPALLK", "length": 182, "header": "tr|A0A8V0Y9C3-1|A0A8V0Y9C3_CHICK Computationally mapped isoform of WASH complex subunit 3 OS=Gallus gallus OX=9031 GN=CCDC53 PE=1 SV=1 CANONICAL=A0A8V0YD47-1" }, "locus": { "chromosome": "1", "start_pos": 55507731, "end_pos": 55495482, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027317.1", "url": "https://www.ensembl.org/id/ENSGALT00010027317.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015571.1", "url": "https://www.ensembl.org/id/ENSGALP00010015571.1" } ] } }, { "isoform_ac": "A0A8V0YAV8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD47/entry#A0A8V0YAV8-1", "sequence": { "sequence": "MISKVPSNPNHSMIHSMILVDFSDRNDSLVKLPKWKKRNINPSAAPGPGAEERRRGTRSAAHAYSPSSLTNYTFHGAPHGQRTCADKPAPSCRAGRGVLFPGRGRLRTRGASGVRAVYRPAGMDEDGLPIVGSGIDLTKVPAIQQKRTVAFLNQFVVHTVQFLNRFSTVCEEKLSALSLRIQQIETTLNILDAKLSSIPGLEDVKFEVSSANLNSVTSSPMAPATTDQQAAVSPQSGQNNKHEEALQKTEIVTENMRTVAKDPRYARYLKMVQVGVPVMAIRNKMISEGLNPDLLETPDAPVPAWGDDGNAEDSSDSESSFSD", "length": 323, "header": "tr|A0A8V0YAV8-1|A0A8V0YAV8_CHICK Computationally mapped isoform of WASH complex subunit 3 OS=Gallus gallus OX=9031 GN=CCDC53 PE=1 SV=1 CANONICAL=A0A8V0YD47-1" }, "locus": { "chromosome": "1", "start_pos": 55509107, "end_pos": 55495116, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027320.1", "url": "https://www.ensembl.org/id/ENSGALT00010027320.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015574.1", "url": "https://www.ensembl.org/id/ENSGALP00010015574.1" } ] } }, { "isoform_ac": "A0A8V0YAW4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD47/entry#A0A8V0YAW4-1", "sequence": { "sequence": "MDEDGLPIVGSGIDLTKVPAIQQKRTVAFLNQFVVHTVQFLNRFSTVCEEKLSALSLRIQQIETTLNILDAKLSSIPGLEDVKFEVSSANLNSVTSSPMAPATTDQQAAVSPQSGQNNKHEEALQKTEIVTENMRTVAKDPRYARYLKMVQVGVPVMAIRNKMISEGLNPDLLESGKKPVSRSSRRVFPSQERMRGSKGGWQSRSRAWS", "length": 209, "header": "tr|A0A8V0YAW4-1|A0A8V0YAW4_CHICK Computationally mapped isoform of WASH complex subunit 3 OS=Gallus gallus OX=9031 GN=CCDC53 PE=1 SV=1 CANONICAL=A0A8V0YD47-1" }, "locus": { "chromosome": "1", "start_pos": 55521176, "end_pos": 55495482, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027325.1", "url": "https://www.ensembl.org/id/ENSGALT00010027325.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015579.1", "url": "https://www.ensembl.org/id/ENSGALP00010015579.1" } ] } }, { "isoform_ac": "A0A8V0YD47-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD47/entry#A0A8V0YD47-1", "sequence": { "sequence": "MISKVPSNPNHSMIHSMILVDFSDRNDSLVKLPKWKKRNINPSAAPGPGAEERRRGTRSAAHAYSPSSLTNYTFHGAPHGQRTCADKPAPSCRAGRGVLFPGRGRLRTRGASGVRAVYRPAGMDEDGLPIVGSGIDLTKVPAIQQKRTVAFLNQFVVHTVQFLNRFSTVCEEKLSALSLRIQQIETTLNILDAKLSSIPGLEDVKFEVSSANLNSVTSSPMAPATTDQQAAVSPQSGQNNKHEEALQKTEIVTENMRTVAKDPRYARYLKMVQVGVPVMAIRNKMISEGLNPDLLEAFFWNIVQADVLLNRRPLVFCQFPDMLKYF", "length": 326, "header": "tr|A0A8V0YD47-1|A0A8V0YD47_CHICK Isoform 1 of WASH complex subunit 3 OS=Gallus gallus OX=9031 GN=CCDC53 PE=1 SV=1 CANONICAL=A0A8V0YD47-1" }, "locus": { "chromosome": "1", "start_pos": 55528736, "end_pos": 55495116, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027326.1", "url": "https://www.ensembl.org/id/ENSGALT00010027326.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015580.1", "url": "https://www.ensembl.org/id/ENSGALP00010015580.1" } ] } }, { "isoform_ac": "A0A8V0YHS8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD47/entry#A0A8V0YHS8-1", "sequence": { "sequence": "MISKVPSNPNHSMIHSMILVDFSDRNDSLVKLPKWKKRNINPSAAPGPGAEERRRGTRSAAHAYSPSSLTNYTFHGAPHGQRTCADKPAPSCRAGRGVLFPGRGRLRTRGASGVRAVYRPAGMDEDGLPIVGSGIDLTKVPAIQQKRTVAFLNQFVVHTVQFLNRFSTVCEEKLSALSLRIQQIETTLNILDAKLSSIPGLEDVKFEVSSANLNSVTSSPMAPATTDQQAAVSPQSGNNKHEEALQKTEIVTENMRTVAKDPRYARYLKMVQVGVPVMAIRNKMISEGLNPDLLETPDAPVPAWGDDGNAEDSSDSESSFSD", "length": 322, "header": "tr|A0A8V0YHS8-1|A0A8V0YHS8_CHICK Computationally mapped isoform of WASH complex subunit 3 OS=Gallus gallus OX=9031 GN=CCDC53 PE=1 SV=1 CANONICAL=A0A8V0YD47-1" }, "locus": { "chromosome": "1", "start_pos": 55509107, "end_pos": 55495116, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027319.1", "url": "https://www.ensembl.org/id/ENSGALT00010027319.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015573.1", "url": "https://www.ensembl.org/id/ENSGALP00010015573.1" } ] } }, { "isoform_ac": "A0A8V0YHT3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD47/entry#A0A8V0YHT3-1", "sequence": { "sequence": "MDEDGLPIVGSGIDLTKVPAIQQKRTVAFLNQFVVHTVQFLNRFSTVCEEKLSALSLRIQQIETTLNILDAKLSSIPGLEDVKFEVSSANLNSVTSSPMAPATTDQQAAVSPQSGQNNKHEEALQKTEIVTENMRTVAKDPRYARYLKMVQVREETCVKEQQKSVSFPREDEGEQRRVAKQEQSMELITQ", "length": 190, "header": "tr|A0A8V0YHT3-1|A0A8V0YHT3_CHICK Computationally mapped isoform of WASH complex subunit 3 OS=Gallus gallus OX=9031 GN=CCDC53 PE=3 SV=1 CANONICAL=A0A8V0YD47-1" }, "locus": { "chromosome": "1", "start_pos": 55521187, "end_pos": 55495482, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027324.1", "url": "https://www.ensembl.org/id/ENSGALT00010027324.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015578.1", "url": "https://www.ensembl.org/id/ENSGALP00010015578.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "actin filament polymerization", "id": "GO:0030041", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030041", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YD47", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD47" } ], "pmid": "" }, { "name": "exocytosis", "id": "GO:0006887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006887", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YD47", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD47" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "WASH complex", "id": "GO:0071203", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071203", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YD47", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD47" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 10, "end_pos": 12, "annotation": "n_glycosylation_sequon" }, { "start_pos": 26, "end_pos": 28, "annotation": "n_glycosylation_sequon" }, { "start_pos": 71, "end_pos": 73, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 10, "end_pos": 12 }, { "start_pos": 26, "end_pos": 28 }, { "start_pos": 71, "end_pos": 73 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YEF6-1", "uniprot_ac": "A0A8V0YEF6", "uniprot_id": "A0A8V0YEF6_CHICK", "mass": { "chemical_mass": 177700.0, "monoisotopic_mass": 177700.0 }, "refseq": { "ac": "XP_001233854", "name": "SET-binding protein isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001233854" }, "gene_names": [ { "name": "SETBP1", "type": "recommended", "evidence": [ { "id": "A0A8V0YEF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEF6" } ] }, { "name": "SETBP1", "type": "synonym", "evidence": [ { "id": "XP_001233854", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001233854" } ] } ], "protein_names": [ { "name": "SET binding protein 1", "type": "synonym", "evidence": [ { "id": "A0A8V0YEF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEF6/entry#names_and_taxonomy" } ] }, { "name": "SET-binding protein isoform X1", "type": "synonym", "evidence": [ { "id": "XP_001233854", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001233854" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052572.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_001233854.3. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_001233854", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001233854" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YEF6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEF6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SETBP1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEF6", "locus": { "chromosome": "Z", "start_pos": 2964919, "end_pos": 3233491, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012148", "url": "https://www.ensembl.org/id/ENSGALG00010012148" } ] } } ], "crossref": [ { "id": "416376", "url": "https://www.ncbi.nlm.nih.gov/gene/416376", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR017956", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017956", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:416376", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416376", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "RHSHRPK", "url": "https://omabrowser.org/oma/group/RHSHRPK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y866", "url": "https://www.orthodb.org/?gene=A0A8V0Y866", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YD59", "url": "https://www.orthodb.org/?gene=A0A8V0YD59", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YEF6", "url": "https://www.orthodb.org/?gene=A0A8V0YEF6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46147", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46147", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46147:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46147:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "XP_001233854", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001233854", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Y866", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y866", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y866-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y866-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YD59", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD59", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YD59-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD59-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YEF6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEF6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YEF6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEF6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEPRESLGSSRQRGGEADFLPASVSSAKPPSASSCTGETVLPTAGSGKGIPVSGERMEPEEEDEMGSGRDVDSTSNADSEKWVAGDGLEEQEFSIKEANFTEGSLKLKIQTTKRAKKPPKNLENYICPPEIKITIKQPGEQKLSRAGKNSKAAKEEDRGHSKKKGKVIGDAKLLMSCGCRKGKNAQMKDSDQNQMKNLGRECGFPVQSPVTKSVNKVYDRPQKHSTLHYDPGLQQDFTGDTLKSKHQQKSSNQHHLDWSASSNTGSTSQSCFINTEPNREAVSATKVTPPEPGVSFSKSQAKKSCASSTWGQLSVSSKELAICSAVPSPNNIGVAAQPSSASECNGLLPIGDQDGGVQLEAPDQSAGSTKKKSSKKDLICQTIQTADIEWVKSTQKAFDSKCHDSMEGKKESYSMDSVLDASPSKQNPASASTCENDTSHVRITIPIKSPTTDTSSHKRKKRQSTKSSMEKVIQEKSLPSGLAMSGEVANRTISQSEGSKKDIRVTKPGKVIENESPLAAIDSSVLIDRASPNSATRLRKSVAVTSTLLSTDLPTASKLSEVQHPKLTAKRRWTCSKPKSILRETSMTTSEKMMVEPPSAYPITPSSPLYTNTDSLTVITPVKKKRGRPKKQPLLTVETIHEGTSTSPVSPINREFPGTKKRKRRRNLAKLAQMVPGEDKSISDLKFHKKVGKLGVLDKKTIKTINKMKTLKRKNILNQILSSCSSNIALKTKIQPPSSAGPTTIDARLGKQINVSKRGTIYIGKKRGRKPRAELQPQPEEPKTAMKHSRPVSSQPENPAVPSNLQSLVASSPAAIHPLSTQLVGTNGNLSPASTETNFSELKTMPNLQPISALPTKTQKGMHSGTWKLSPPRLMANSPSHLCEIGSLKEVTLSPVSESHSEETIPSDSGIGTDNNSTSDQAEKSSESRRRYSFDFCTLDNPEAIPSDTSTKNRHGHRQKHLIVDNFLSHESMKKPKHKRKRKSLQNRDDLQFLADLEELINKFQVFRISHRSYTFYHENPYPSIFRINFDHYYPVPYIQYDPLLYLRRTSDMKSKKKRGRPAKTNDTMTKVPFLQGFGYPIPSGSYYAPYGMPYTSMPMMNLGYYGQYPAPLYLSHTLGAASPFMRPTVPPPQFHASSHMKMSTTAKHKAKHGVHLQTPVGMGLGDMQSSLAPPKVGGTSLSSGRLHKRKHKHKHKHKDERILGTHEDLSGLFASKSTGFSSHSINERLSGSDKDLSLLNEKSKHKEKQKHQHCETGHKGSKSNFEVDTLSTLSLSDAQQWTQSKDKSDSSNDPIDSCTKRYSGNTESNARSESLDMFGEMNSSSEKRDNDGSGNKRRSFEGFGTYREKDIQPFRINRKDRSTYDSSASSGIVGPHLKADQTSLHSKMESSACNMMTRRKPATVESVTMPTPVLSLLPSSSATSEAASPPLKKRFKRREIEAIQCEVRKMCNYTKILSTKKNLDHVNKILKAKRLQRQSKTGNNFVKKRRGRPRKQPLSFDEDSRDQMPVLEKCIDLPSKRGQKPTLNPLLLEQAATQDTIMATIEAVIHMARETPPPPPPLPPPPPPPPLPLPRTPRLGKRKSKSPQEEEDDMKVKRHRKGRGSESEGLP", "length": 1612, "header": "tr|A0A8V0YEF6-1|A0A8V0YEF6_CHICK Isoform 1 of SET binding protein 1 OS=Gallus gallus OX=9031 GN=SETBP1 PE=4 SV=1 CANONICAL=A0A8V0YEF6-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Y866-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEF6/entry#A0A8V0Y866-1", "sequence": { "sequence": "MEPRESLGSSRQRGGEADFLPASVSSAKPPSASSCTGETVLPTAGSGKGIPVSGERMEPEEEDEMGSGRDVDSTSNADSEKWVAGDGLEEQEFSIKEANFTEGSLKLKIQTTKRAKKPPKNLENYICPPEIKITIKQPGEQKLSRAGKNSKAAKEEDRGHSKKKGKVIGDAKLLMSCGCRKGKNAQMKDSDQNQMKNLGRECGFPVQSPVTKSVNKVYDRPQKHSTLHYDPGLQQDFTGDTLKSKHQQKSSNQHHLDWSASSNTGSTSQSCFINTEPNREAVSATKVTPPEPGVSFSKSQAKKSCASSTWGQLSVSSKELAICSAVPSPNNIGVAAQPSSASECNGLLPIGDQDGGVQLEAPDQSAGSTKKKSSKKDLICQTIQTADIEWVKSTQKAFDSKCHDSMEGKKESYSMDSVLDASPSKQNPASASTCENDTSHVRITIPIKSPTTDTSSHKRKKRQSTKSSMEKVIQEKSLPSGLAMSGEVANRTISQSEGSKKDIRVTKPGKVIENESPLAAIDSSVLIDRASPNSATRLRKSVAVTSTLLSTDLPTASKLSEVQHPKLTAKRRWTCSKPKSILRETSMTTSEKMMVEPPSAYPITPSSPLYTNTDSLTVITPVKKKRGRPKKQPLLTVETIHEGTSTSPVSPINREFPGTKKRKRRRNLAKLAQMVPGEDKSISDLKFHKKVGKLGVLDKKTIKTINKMKTLKRKNILNQILSSCSSNIALKTKIQPPSSAGPTTIDARLGKQINVSKRGTIYIGKKRGRKPRAELQPQPEEPKTAMKHSRPVSSQPENPAVPSNLQSLVASSPAAIHPLSTQLVGTNGNLSPASTETNFSELKTMPNLQPISALPTKTQKGMHSGTWKLSPPRLMANSPSHLCEIGSLKEVTLSPVSESHSEETIPSDSGIGTDNNSTSDQAEKSSESRRRYSFDFCTLDNPEAIPSDTSTKNRHGHRQKHLIVDNFLSHESMKKPKHKRKRKSLQNRDDLQFLADLEELINKFQVFRISHRSYTFYHENPYPSIFRINFDHYYPVPYIQYDPLLYLRRTSDMKSKKKRGRPAKTNDTMTKVPFLQGFGYPIPSGSYYAPYGMPYTSMPMMNLGYYGQYPAPLYLSHTLGAASPFMRPTVPPPQFHASSHMKMSTTAKHKAKHGVHLQTPVGMGLGDMQSSLAPPKVGGTSLSSGRLHKRKHKHKHKHKDERILGTHEDLSGLFASKSTGFSSHSINERLSGSDKDLSLLNEKSKHKEKQKHQHCETGHKGSKSNFEVDTLSTLSLSDAQQWTQSKDKSDSSNDPIDSCTKRYSGNTESNARSESLDMFGEMNSSSEKRDNDGSGNKRRSFEGFGTYREKDIQPFRINRKDRSTYDSSASSASPPLKKRFKRREIEAIQCEVRKMCNYTKILSTKKNLDHVNKILKAKRLQRQSKTGNNFVKKRRGRPRKQPLSFDEDSRDQMPVLEKCIDLPSKRGQKPTLNPLLLEQAATQDTIMATIEAVIHMARETPPPPPPLPPPPPPPPLPLPRTPRLGKRKSKSPQEEEDDMKVKRHRKGRGSESEGLP", "length": 1556, "header": "tr|A0A8V0Y866-1|A0A8V0Y866_CHICK Computationally mapped isoform of SET binding protein 1 OS=Gallus gallus OX=9031 GN=SETBP1 PE=4 SV=1 CANONICAL=A0A8V0YEF6-1" }, "locus": { "chromosome": "Z", "start_pos": 3213886, "end_pos": 2965373, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029136.1", "url": "https://www.ensembl.org/id/ENSGALT00010029136.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016890.1", "url": "https://www.ensembl.org/id/ENSGALP00010016890.1" } ] } }, { "isoform_ac": "A0A8V0YD59-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEF6/entry#A0A8V0YD59-1", "sequence": { "sequence": "MEPRESLGSSRQRGGEADFLPASVSSAKPPSASSCTGETVLPTAGSGKGIPVSGERMEPEEEDEMGSGRDVDSTSNADSEKWVAGDGLEEQEFSIKEANFTEGSLKLKIQTTKRAKKPPKNLENYICPPEIKITIKQPGEQKLSRAGKNSKAAKEEDRGHSKKKNQMKNLGRECGFPVQSPVTKSVNKVYDRPQKHSTLHYDPGLQQDFTGDTLKSKHQQKSSNQHHLDWSASSNTGSTSQSCFINTEPNREAVSATKVTPPEPGVSFSKSQAKKSCASSTWGQLSVSSKELAICSAVPSPNNIGVAAQPSSASECNGLLPIGDQDGGVQLEAPDQSAGSTKKKSSKKDLICQTIQTADIEWVKSTQKAFDSKCHDSMEGKKESYSMDSVLDASPSKQNPASASTCENDTSHVRITIPIKSPTTDTSSHKRKKRQSTKSSMEKVIQEKSLPSGLAMSGEVANRTISQSEGSKKDIRVTKPGKVIENESPLAAIDSSVLIDRASPNSATRLRKSVAVTSTLLSTDLPTASKLSEVQHPKLTAKRRWTCSKPKSILRETSMTTSEKMMVEPPSAYPITPSSPLYTNTDSLTVITPVKKKRGRPKKQPLLTVETIHEGTSTSPVSPINREFPGTKKRKRRRNLAKLAQMVPGEDKSISDLKFHKKVGKLGVLDKKTIKTINKMKTLKRKNILNQILSSCSSNIALKTKIQPPSSAGPTTIDARLGKQINVSKRGTIYIGKKRGRKPRAELQPQPEEPKTAMKHSRPVSSQPENPAVPSNLQSLVASSPAAIHPLSTQLVGTNGNLSPASTETNFSELKTMPNLQPISALPTKTQKGMHSGTWKLSPPRLMANSPSHLCEIGSLKEVTLSPVSESHSEETIPSDSGIGTDNNSTSDQAEKSSESRRRYSFDFCTLDNPEAIPSDTSTKNRHGHRQKHLIVDNFLSHESMKKPKHKRKRKSLQNRDDLQFLADLEELINKFQVFRISHRSYTFYHENPYPSIFRINFDHYYPVPYIQYDPLLYLRRTSDMKSKKKRGRPAKTNDTMTKVPFLQGFGYPIPSGSYYAPYGMPYTSMPMMNLGYYGQYPAPLYLSHTLGAASPFMRPTVPPPQFHASSHMKMSTTAKHKAKHGVHLQTPVGMGLGDMQSSLAPPKVGGTSLSSGRLHKRKHKHKHKHKDERILGTHEDLSGLFASKSTGFSSHSINERLSGSDKDLSLLNEKSKHKEKQKHQHCETGHKGSKSNFEVDTLSTLSLSDAQQWTQSKDKSDSSNDPIDSCTKRYSGNTESNARSESLDMFGEMNSSSEKRDNDGSGNKRRSFEGFGTYREKDIQPFRINRKDRSTYDSSASSGIVGPHLKADQTSLHSKMESSACNMMTRRKPATVESVTMPTPVLSLLPSSSATSEAASPPLKKRFKRREIEAIQCEVRKMCNYTKILSTKKNLDHVNKILKAKRLQRQSKTGNNFVKKRRGRPRKQPLSFDEDSRDQMPVLEKCIDLPSKRGQKPTLNPLLLEQAATQDTIMATIEAVIHMARETPPPPPPLPPPPPPPPLPLPRTPRLGKRKSKSPQEEEDDMKVKRHRKGRGSESEGLP", "length": 1584, "header": "tr|A0A8V0YD59-1|A0A8V0YEF6_CHICK Computationally mapped isoform of SET binding protein 1 OS=Gallus gallus OX=9031 GN=SETBP1 PE=4 SV=1 CANONICAL=A0A8V0YEF6-1" }, "locus": { "chromosome": "Z", "start_pos": 3213886, "end_pos": 2965373, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029133.1", "url": "https://www.ensembl.org/id/ENSGALT00010029133.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016889.1", "url": "https://www.ensembl.org/id/ENSGALP00010016889.1" } ] } }, { "isoform_ac": "A0A8V0YEF6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEF6/entry#A0A8V0YEF6-1", "sequence": { "sequence": "MEPRESLGSSRQRGGEADFLPASVSSAKPPSASSCTGETVLPTAGSGKGIPVSGERMEPEEEDEMGSGRDVDSTSNADSEKWVAGDGLEEQEFSIKEANFTEGSLKLKIQTTKRAKKPPKNLENYICPPEIKITIKQPGEQKLSRAGKNSKAAKEEDRGHSKKKGKVIGDAKLLMSCGCRKGKNAQMKDSDQNQMKNLGRECGFPVQSPVTKSVNKVYDRPQKHSTLHYDPGLQQDFTGDTLKSKHQQKSSNQHHLDWSASSNTGSTSQSCFINTEPNREAVSATKVTPPEPGVSFSKSQAKKSCASSTWGQLSVSSKELAICSAVPSPNNIGVAAQPSSASECNGLLPIGDQDGGVQLEAPDQSAGSTKKKSSKKDLICQTIQTADIEWVKSTQKAFDSKCHDSMEGKKESYSMDSVLDASPSKQNPASASTCENDTSHVRITIPIKSPTTDTSSHKRKKRQSTKSSMEKVIQEKSLPSGLAMSGEVANRTISQSEGSKKDIRVTKPGKVIENESPLAAIDSSVLIDRASPNSATRLRKSVAVTSTLLSTDLPTASKLSEVQHPKLTAKRRWTCSKPKSILRETSMTTSEKMMVEPPSAYPITPSSPLYTNTDSLTVITPVKKKRGRPKKQPLLTVETIHEGTSTSPVSPINREFPGTKKRKRRRNLAKLAQMVPGEDKSISDLKFHKKVGKLGVLDKKTIKTINKMKTLKRKNILNQILSSCSSNIALKTKIQPPSSAGPTTIDARLGKQINVSKRGTIYIGKKRGRKPRAELQPQPEEPKTAMKHSRPVSSQPENPAVPSNLQSLVASSPAAIHPLSTQLVGTNGNLSPASTETNFSELKTMPNLQPISALPTKTQKGMHSGTWKLSPPRLMANSPSHLCEIGSLKEVTLSPVSESHSEETIPSDSGIGTDNNSTSDQAEKSSESRRRYSFDFCTLDNPEAIPSDTSTKNRHGHRQKHLIVDNFLSHESMKKPKHKRKRKSLQNRDDLQFLADLEELINKFQVFRISHRSYTFYHENPYPSIFRINFDHYYPVPYIQYDPLLYLRRTSDMKSKKKRGRPAKTNDTMTKVPFLQGFGYPIPSGSYYAPYGMPYTSMPMMNLGYYGQYPAPLYLSHTLGAASPFMRPTVPPPQFHASSHMKMSTTAKHKAKHGVHLQTPVGMGLGDMQSSLAPPKVGGTSLSSGRLHKRKHKHKHKHKDERILGTHEDLSGLFASKSTGFSSHSINERLSGSDKDLSLLNEKSKHKEKQKHQHCETGHKGSKSNFEVDTLSTLSLSDAQQWTQSKDKSDSSNDPIDSCTKRYSGNTESNARSESLDMFGEMNSSSEKRDNDGSGNKRRSFEGFGTYREKDIQPFRINRKDRSTYDSSASSGIVGPHLKADQTSLHSKMESSACNMMTRRKPATVESVTMPTPVLSLLPSSSATSEAASPPLKKRFKRREIEAIQCEVRKMCNYTKILSTKKNLDHVNKILKAKRLQRQSKTGNNFVKKRRGRPRKQPLSFDEDSRDQMPVLEKCIDLPSKRGQKPTLNPLLLEQAATQDTIMATIEAVIHMARETPPPPPPLPPPPPPPPLPLPRTPRLGKRKSKSPQEEEDDMKVKRHRKGRGSESEGLP", "length": 1612, "header": "tr|A0A8V0YEF6-1|A0A8V0YEF6_CHICK Isoform 1 of SET binding protein 1 OS=Gallus gallus OX=9031 GN=SETBP1 PE=4 SV=1 CANONICAL=A0A8V0YEF6-1" }, "locus": { "chromosome": "Z", "start_pos": 3213886, "end_pos": 2965373, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029139.1", "url": "https://www.ensembl.org/id/ENSGALT00010029139.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016892.1", "url": "https://www.ensembl.org/id/ENSGALP00010016892.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 604, "start_aa": "Thr", "end_pos": 604, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr604", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:416376", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416376", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6A7F2-1", "protein_name": "SET binding protein 1", "gene_name": "Setbp1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MESREILSSSRQRGSESEFLPGSSSRSPATPGCSGEPLKGISVGGERIEPEEEDELGSGRDVDCNSNADSEKWVAGDGLEEQEFSIKEANFSEGSLKLKIQTTKRAKKPPKNLENYICPPEIKITIKQSGDQKVSRAGKNGKATKEEERNHSKKKLLTASDPAASDLKGFQTQAYERPQKHSTLQYDPGLSQGFTSDTLKPKHQQKSSSQSHMDWSSNSDSGPATQNCIISPESGRDTTSTSKIPALEPVASFAKTQSKKGSTGSTWSQLSSSSKDLLLGSVVPSPGSHSSPATPSNSAECNGLQPLGDQEGGGTKDLPEPPTISSKKKSSKKDLISQTIPNSDLDWVKSAQKAFETTEGKRETYSADNAQETSPTRQSISSVSNPENDSSHVRITIPIKTPSLDPTNHKRKKRQSIKAVVEKIIPEKALASGITMSSEVVNRILSNSEGSKKDPRVPKLSKMIENESPSVGLETGANAEKIVPGGVSKQRKPPLVMTSPTRAEHAPSGKLPEIQHPKFAAKRRCSKAKPPAMLREAVLATAEKLMVEPPSAYPITPSSPLYTNTDSLTVITPVKKKRGRPKKQPLLTVETIHEGTSTSPVSPISREFPGTKKRKRRRNLAKLAQLVPGEDKPMSEMKFHKKVGKLGVLDKKTIKTINKMKTLKRKNILNQILSCSSSVALKAKAPPETSPGAASIESKLGKQINVSKRGTIYIGKKRGRKPRTELPPPSEEPKTAIKHPRPVSSQPDVPAVPSSFQSPVASSPAAVHPLATQLGGSHGNLSPASTETNFSELKTMPNLQPISALPTKTQKGIHSGTWKLSPPRLMANSPSHLCEIGSLKEITLSPVSESHSEETIPSDSGIGTDNNSTSDQAEKSSESRRRYSFDFCSLDNPEAIPPDTSTKNRHGHRQKHLIVDTFLAHESLKKPKHKRKRKSLQNRDDLQFLAELEELITKFQVFRISHRGYTFYHENPYPSIFRINFDHYYPVPYIQYDPLLYLRRTSDLKSKKKRGRPAKTNDTMTKVPFLQGFSYPIPSGSYYAPYGMPYTSMPMMNLGYYGQYPAPLYLSHTLGAASPFMRPTVPPPQFHTSSHVKMSGATKHKAKHGVHLQGTVGMGLGDIQPSLNPPKVGGAALSSSRLHKRKHKHKHKHKEDRILGTHDNLSGLFAGKATGFSSHLLSERLNSSDKELPLVSEKSKHKERQKHQHGDASHKVSKNNFEVDTLSTLSLSDAQHWTQAKDKGDLSNEPVESCAKRYSGSGGDSTRSESLDVFSEMNPSSDKWDSDMSGSKRRGFEGFGTYREKDIQAFKMNRKERGSYESSMTPGMPSPHLKVDQTTVHSKSEGSVSTMMARKKPTAVDSVAIPSAPVLSLLAASAATSDAASSSLKKRFKRREIEAIQCEVRKMCHYTKLLSTKKNLDHVNKILKAKRLQRQSKTGNNFVKKRRGRPRKQPSQFDEDSRDQMPVLEKCIDLPSKRGQKPSLSPLALEPASGQDAVMATIEAVIHMAREAPPLPPPPPPLPPPPPPPPPPPPPLPKTSRGGKRKHRPQPPAQPAQPPPQPLPQEEEVKAKRPRKSRASESDVLP", "length": 1582 }, "evidence": [ { "id": "A0A8V0YEF6", "url": "https://omabrowser.org/oma/group/A0A8V0YEF6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9Y6X0-1", "protein_name": "SET-binding protein", "gene_name": "SETBP1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MESRETLSSSRQRGGESDFLPVSSAKPPAAPGCAGEPLLSTPGPGKGIPVGGERMEPEEEDELGSGRDVDSNSNADSEKWVAGDGLEEQEFSIKEANFTEGSLKLKIQTTKRAKKPPKNLENYICPPEIKITIKQSGDQKVSRAGKNSKATKEEERSHSKKKLLTASDLAASDLKGFQPQAYERPQKHSTLHYDTGLPQDFTGDTLKPKHQQKSSSQNHMDWSTNSDSGPVTQNCFISPESGRETASTSKIPALEPVASFAKAQGKKGSAGNTWSQLSNNNKDLLLGGVAPSPSSHSSPAPPSSSAECNGLQPLVDQDGGGTKEPPEPPTVGSKKKSSKKDVISQTIPNPDLDWVKNAQKAFDNTEGKREGYSADSAQEASPARQNVSSASNPENDSSHVRITIPIKAPSLDPTNHKRKKRQSIKAVVEKIMPEKALASGITMSSEVVNRILSNSEGNKKDPRVPKLSKMIENESPSVGLETGGNAEKVIPGGVSKPRKPPMVMTPPTCTDHSPSRKLPEIQHPKFAAKRRWTCSKPKPSTMLREAVMATSDKLMLEPPSAYPITPSSPLYTNTDSLTVITPVKKKRGRPKKQPLLTVETIHEGTSTSPVSPISREFPGTKKRKRRRNLAKLAQLVPGEDKPMSEMKFHKKVGKLGVLDKKTIKTINKMKTLKRKNILNQILSCSSSVALKAKAPPETSPGAAAIESKLGKQINVSKRGTIYIGKKRGRKPRAELPPPSEEPKTAIKHPRPVSSQPDVPAVPSNFQSLVASSPAAMHPLSTQLGGSNGNLSPASTETNFSELKTMPNLQPISALPTKTQKGIHSGTWKLSPPRLMANSPSHLCEIGSLKEITLSPVSESHSEETIPSDSGIGTDNNSTSDQAEKSSESRRRYSFDFCSLDNPEAIPSDTSTKNRHGHRQKHLIVDNFLAHESLKKPKHKRKRKSLQNRDDLQFLADLEELITKFQVFRISHRSYTFYHENPYPSIFRINFDHYYPVPYIQYDPLLYLRRTSDLKSKKKRGRPAKTNDTMTKVPFLQGFSYPIPSGSYYAPYGMPYTSMPMMNLGYYGQYPAPLYLSHTLGAASPFMRPTVPPPQFHTNSHVKMSGAAKHKAKHGVHLQGPVSMGLGDMQPSLNPPKVGSASLSSGRLHKRKHKHKHKHKEDRILGTHDNLSGLFAGKATGFSSHILSERLSSADKELPLVSEKNKHKEKQKHQHSEAGHKASKNNFEVDTLSTLSLSDAQHWTQAKEKGDLSSEPVDSCTKRYSGSGGDGGSTRSENLDVFSEMNPSNDKWDSDVSGSKRRSYEGFGTYREKDIQAFKMNRKERSSYDSSMSPGMPSPHLKVDQTAVHSKNEGSVPTMMTRKKPAAVDSVTIPPAPVLSLLAASAATSDAVGSSLKKRFKRREIEAIQCEVRKMCNYTKILSTKKNLDHVNKILKAKRLQRQSKTGNNFVKKRRGRPRKQPTQFDEDSRDQMPVLEKCIDLPSKRGQKPSLSPLVLEPAASQDTIMATIEAVIHMAREAPPLPPPPPPPLPPPPPPPLPPPPPLPKTPRGGKRKHKPQAPAQPPQQSPPQQPLPQEEEVKAKRQRKSRGSESEVLP", "length": 1596 }, "evidence": [ { "id": "A0A8V0YEF6", "url": "https://omabrowser.org/oma/group/A0A8V0YEF6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9Z180-1", "protein_name": "SET-binding protein", "gene_name": "Setbp1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEPREMLSSCRQRGSESEFLQGSSSRSPPAPGCSGEPLKGISVGGERMEPEEEDELGSGRDVDCNSNADSEKWVAGDGLEEQEFSIKEANFTEGSLKLKIQTTKRAKKPPKNLENYICPPEIKITIKQSGDQKVSRTGKNSKATKEDERNHSKKKLLTAGDPTASDLKAFQTQAYERPQKHSTLQYDPGHSQGFTSDTLKPKHQQKSSSQSHMEWSSNSDSGPATQNCFISPEAGRDTASTSKVPALEPVASFAKAQSKKGSTGGAWSQLSSSSKDLLLGSVVPSPSSHNSPATPSSSAECNGLQPLGDQDGGSTKDLPEPPTLSSKKKSSKKDMISQTLPNSDLDWVKSAQKAFETTEGKREAYSADSAQEASPARQSISSVSNPENDSSHVRITIPIKTPSLDPSNHKRKKRQSIKAVVEKIVPEKALASGISMSSEVVNRILSNSEGSKKDPRVPKLGKMIENETPSVGLETGGNAEKIVPGGASKQRKPPMVMTSPTRTEHAPSGKLSEIQHPKFAAKRRCSKAKPPAMLREAVLATAEKLMVEPPSAYPITPSSPLYTNTDSLTVITPVKKKRGRPKKQPLLTVETIHEGTSTSPVSPISREFPGTKKRKRRRNLAKLAQLVPGEDKPMSEMKFHKKVGKLGVLDKKTIKTINKMKTLKRKNILNQILSCSSSVALKAKAPPETSPGAASIESKLGKQINVSKRGTIYIGKKRGRKPRTELPPPSEEPKTAIKHPRPVSSQPDVPAVPSSFQSPVASSPAAMHPLSTQLGGSNGNLSPASTETNFSELKTMPNLQPISALPTKTQKGIHGGTWKLSPPRLMANSPSHLCEIGSLKEITLSPVSESHSEETIPSDSGIGTDNNSTSDQAEKSSESRRRYSFDFCSLDNPEAIPSDTSTKNRHGHRQKHLIVDTFLAHESLKKPKHKRKRKSLQNRDDLQFLAELEELITKFQVFRISHRGYTFYHENPYPSIFRINFDQYYPVPYIQYDPLLYLRRTSDLKSKKKRGRPAKTNDTMTKVPFLQGFSYPIPSGSYYAPYGMPYTSMPMMNLGYYGQYPAPLYLSHTLGAASPFMRPTVPPPQFHASSHVKISGATKHKAKHGVHLQGTVGMGLGDIQPSLNPPKVGGATLSSSRLHKRKHKHKRKHKEDRILGTHDNLSGLFAGKATGFSSHLLSERLSGSDKELPLVSEKSKHKERQKHQHGEASHKVSKNNFEVDTLSTLSLSDAQHWTQAKDKGDLSSEPVESCAKRYSGSGGDSTRSEGLDVFSEMNPSSDKWDSDMGGSKRRSFEGFGTYREKDIQAFKMNRKERGSYESSMSPGMPSPHLKVDQTAAHSKSEGSISAMMARKKPTAVDSVAIPSAPVLSLLAASAATSDAASSSLKKRFKRREIEAIQCEVRKMCHYTKLLSTKKNLDHVNKILKAKRLQRQSKTGNNFVKKRRGRPRKQPSQFDEDSRDQMPVLEKCIDLPSKRGQKPSLSPLALEPASGQDAVMATIEAVIHMAREAPPLPPPPPPPLPPPPPPPPPPPPLPKTARGGKRKHRPQPPAQPAQPTPQPLPQEEEVKAKRPRKSRASESDVLP", "length": 1582 }, "evidence": [ { "id": "A0A8V0YEF6", "url": "https://omabrowser.org/oma/group/A0A8V0YEF6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YEF6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEF6" } ], "pmid": "" }, { "name": "histone H3K4 methyltransferase activity", "id": "GO:0042800", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042800", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YEF6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEF6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YEF6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEF6" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YEF6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEF6" } ], "pmid": "" }, { "name": "nuclear membrane", "id": "GO:0031965", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031965", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YEF6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEF6" } ], "pmid": "" }, { "name": "nuclear body", "id": "GO:0016604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016604", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YEF6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEF6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YEF6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEF6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1066, "end_pos": 1068, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1323, "end_pos": 1325, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1453, "end_pos": 1455, "annotation": "n_glycosylation_sequon" }, { "start_pos": 436, "end_pos": 438, "annotation": "n_glycosylation_sequon" }, { "start_pos": 490, "end_pos": 492, "annotation": "n_glycosylation_sequon" }, { "start_pos": 514, "end_pos": 516, "annotation": "n_glycosylation_sequon" }, { "start_pos": 754, "end_pos": 756, "annotation": "n_glycosylation_sequon" }, { "start_pos": 829, "end_pos": 831, "annotation": "n_glycosylation_sequon" }, { "start_pos": 838, "end_pos": 840, "annotation": "n_glycosylation_sequon" }, { "start_pos": 915, "end_pos": 917, "annotation": "n_glycosylation_sequon" }, { "start_pos": 916, "end_pos": 918, "annotation": "n_glycosylation_sequon" }, { "start_pos": 99, "end_pos": 101, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 604 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1066, "end_pos": 1068 }, { "start_pos": 1323, "end_pos": 1325 }, { "start_pos": 1453, "end_pos": 1455 }, { "start_pos": 436, "end_pos": 438 }, { "start_pos": 490, "end_pos": 492 }, { "start_pos": 514, "end_pos": 516 }, { "start_pos": 754, "end_pos": 756 }, { "start_pos": 829, "end_pos": 831 }, { "start_pos": 838, "end_pos": 840 }, { "start_pos": 915, "end_pos": 917 }, { "start_pos": 916, "end_pos": 918 }, { "start_pos": 99, "end_pos": 101 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YD99-1", "uniprot_ac": "A0A8V0YD99", "uniprot_id": "A0A8V0YD99_CHICK", "mass": { "chemical_mass": 57453.0, "monoisotopic_mass": 57453.0 }, "refseq": { "ac": "NP_001384042", "name": "ADP-ribosylation factor GTPase-activating protein 3 isoform a", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384042" }, "gene_names": [ { "name": "ARFGAP3", "type": "recommended", "evidence": [ { "id": "A0A8V0YD99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD99" } ] }, { "name": "ARFGAP3", "type": "synonym", "evidence": [ { "id": "NP_001384042", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384042" } ] } ], "protein_names": [ { "name": "ADP-ribosylation factor GTPase-activating protein 3", "type": "recommended", "evidence": [ { "id": "A0A8V0YD99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD99/entry#names_and_taxonomy" } ] }, { "name": "ADP-ribosylation factor GTPase-activating protein 3 isoform a", "type": "synonym", "evidence": [ { "id": "NP_001384042", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384042" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: HAEK01091527.1, SRR13267648.22938.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA103992290, SAMEA103992323 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000012.1. On Nov 3, 2021 this sequence version replaced XP_015145947.2.", "evidence": [ { "database": "RefSeq", "id": "NP_001384042", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384042" } ] }, { "annotation": "GTPase-activating protein (GAP) for ADP ribosylation factor 1 (ARF1). Hydrolysis of ARF1-bound GTP may lead to dissociation of coatomer from Golgi-derived membranes to allow fusion with target membranes.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YD64", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD64#function" }, { "database": "UniProtKB", "id": "ARBA00037105", "url": "https://www.uniprot.org/uniprotkb/ARBA00037105#function" }, { "database": "UniProtKB", "id": "A0A8V0YD81", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD81#function" }, { "database": "UniProtKB", "id": "A0A8V0YD99", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD99#function" }, { "database": "UniProtKB", "id": "A0A8V0YGM3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGM3#function" }, { "database": "UniProtKB", "id": "A0A8V0YGP1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGP1#function" }, { "database": "UniProtKB", "id": "A0A8V0YLF1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLF1#function" }, { "database": "UniProtKB", "id": "A0A8V0Y8A2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y8A2#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YD99", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD99" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ARFGAP3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD99", "locus": { "chromosome": "1", "start_pos": 68447853, "end_pos": 68482097, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012147", "url": "https://www.ensembl.org/id/ENSGALG00010012147" } ] } } ], "crossref": [ { "id": "A0A8V0YD99", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YD99", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd09028", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09028", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "418224", "url": "https://www.ncbi.nlm.nih.gov/gene/418224", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001164", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001164", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037278", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037278", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038508", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038508", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y8A2", "url": "https://www.orthodb.org/?gene=A0A8V0Y8A2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YD64", "url": "https://www.orthodb.org/?gene=A0A8V0YD64", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YD81", "url": "https://www.orthodb.org/?gene=A0A8V0YD81", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YD99", "url": "https://www.orthodb.org/?gene=A0A8V0YD99", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YGK9", "url": "https://www.orthodb.org/?gene=A0A8V0YGK9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YGM3", "url": "https://www.orthodb.org/?gene=A0A8V0YGM3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YGP1", "url": "https://www.orthodb.org/?gene=A0A8V0YGP1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YLF1", "url": "https://www.orthodb.org/?gene=A0A8V0YLF1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45686", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45686", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45686:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45686:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01412", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01412", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-6807878", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6807878", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-6811434", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6811434", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9013408", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013408", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001384042", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384042", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Y8A2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y8A2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y8A2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y8A2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YD64", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD64", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YD64-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD64-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YD81", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD81", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YD81-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD81-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YD99", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD99", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YD99-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD99-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YGK9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGK9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YGK9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGK9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YGM3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGM3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YGM3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGM3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YGP1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGP1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YGP1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGP1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLF1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLF1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLF1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLF1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MCEPSKQDIGAIFKRLRSVPTNKVCFDCGSKNPSWASITYGVFLCIDCSGTHRSLGVHLSFIRSTELDSNWSWFQLRCMQVGGNANASAFFHQHGCTTNDTNAKYNSRAAQLYKEKIKSLATQATRKHGTDLWTDGCGMPPASPQHKEEDFFASHASSKNTEWVLSEPEPAPLQQKASENIPESYEGGPEHGPSVDCLSTSPKATLENTSFIKKKPNQVKKGLGAKKGGLGAQKVSSQSFNEIEKQAQAVDKMKEQEDLHSSRKIEMEEPLVSSLRLAYRDLDIKTKEEKLNLSGKKKNELERLGMGFGSNRSGISHSVLSDMQTIEQETPTIGKPKKKYTDDVEDSYFSSSSSRYYDSSDLRSNTFSKWDDNSDPFWKKESNNRDVDVILTPKNTGFSDRPASRRKPEYEPSLSTDEAQKKFGNVKAISSDMYFGRQDHADYEARARLERLSGSSSISSADLFEDQKKQPAGGYNITNVLPSAPDIAQFKQGVKSVAGKLSVLANGVMTSIQDRYGS", "length": 518, "header": "tr|A0A8V0YD99-1|A0A8V0YD99_CHICK Isoform 1 of ADP-ribosylation factor GTPase-activating protein 3 OS=Gallus gallus OX=9031 GN=ARFGAP3 PE=1 SV=1 CANONICAL=A0A8V0YD99-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Y8A2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD99/entry#A0A8V0Y8A2-1", "sequence": { "sequence": "MAPLRDATQECELAANQVCFDCGSKNPSWASITYGVFLCIDCSGTHRSLGVHLSFIRSTELDSNWSWFQLRCMQVGGNANASAFFHQHGCTTNDTNAKYNSRAAQLYKEKIKSLATQATRKHGTDLWTDGCGMPPASPQHKEEDFFASHASSKNTEWVLSEPEPAPLQQKASENIPESYEGGPEHGPSVDCLSTSPKATLENTSFIKKKPNQVKKGLGAKKGGLGAQKVSSQSFNEIEKQAQAVDKMKEQEDLHSSRKIEMEEPLVSSLRLAYRDLDIKTKEEKLNLSGKKKNELERLGMGFGSNRSGISHSVLSDMQTIEQETPTIGKPKKKYTDDVEDSYFSSSSSRYYDSSDLRSNTFSKWDDNSDPFWKKESNNRDVDVILTPKNTGFSDRPASRRKPEYEPSLSTDEAQKKFGNVKAISSDMYFGRQDHADYEARARLERLSGSSSISSADLFEDQKKQPAGGYNITNVLPSAPDIAQFKQGVKSVAGKLSVLANGVMTSIQDRYGS", "length": 512, "header": "tr|A0A8V0Y8A2-1|A0A8V0Y8A2_CHICK Computationally mapped isoform of ADP-ribosylation factor GTPase-activating protein 3 OS=Gallus gallus OX=9031 GN=ARFGAP3 PE=1 SV=1 CANONICAL=A0A8V0YD99-1" }, "locus": { "chromosome": "1", "start_pos": 68480083, "end_pos": 68449453, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029184.1", "url": "https://www.ensembl.org/id/ENSGALT00010029184.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016926.1", "url": "https://www.ensembl.org/id/ENSGALP00010016926.1" } ] } }, { "isoform_ac": "A0A8V0YD64-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD99/entry#A0A8V0YD64-1", "sequence": { "sequence": "MHKLMIFVFFKVCFDCGSKNPSWASITYGVFLCIDCSGTHRSLGVHLSFIRSTELDSNWSWFQLRCMQVGGNANASAFFHQHGCTTNDTNAKYNSRAAQLYKEKIKSLATQATRKHGTDLWTDGCGMPPASPQHKEEDFFASHASSKNTEWVLSEPEPAPLQQKASENIPESYEGGPEHGPSVDCLSTSPKATLENTSFIKKKPNQVKKGLGAKKGGLGAQKVSSQSFNEIEKQAQAVDKMKEQEDLHSSRKIEMEEPLVSSLRLAYRDLDIKTKEEKLNLSGKKKNELERLGMGFGSNRSGISHSVLSDMQTIEQETPTIGKPKKKYTDDVEDSYFSSSSSRYYDSSDLRSNTFSKWDDNSDPFWKKESNNRDVDVILTPKNTGFSDRPASRRKPEYEPSLSTDEAQKKFGNVKAISSDMYFGRQDHADYEARARLERLSGSSSISSADLFEDQKKQPAGGYNITNVLPSAPDIAQFKQGVKSVAGKLSVLANGVMTSIQDRYGS", "length": 506, "header": "tr|A0A8V0YD64-1|A0A8V0YD99_CHICK Computationally mapped isoform of ADP-ribosylation factor GTPase-activating protein 3 OS=Gallus gallus OX=9031 GN=ARFGAP3 PE=1 SV=1 CANONICAL=A0A8V0YD99-1" }, "locus": { "chromosome": "1", "start_pos": 68477300, "end_pos": 68449453, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029144.1", "url": "https://www.ensembl.org/id/ENSGALT00010029144.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016894.1", "url": "https://www.ensembl.org/id/ENSGALP00010016894.1" } ] } }, { "isoform_ac": "A0A8V0YD81-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD99/entry#A0A8V0YD81-1", "sequence": { "sequence": "MCEPSKQDIGAIFKRLRSVPTNKVCFDCGSKNPSWASITYGVFLCIDCSGTHRSLGVHLSFIRSTELDSNWSWFQLRCMQVGGNANASAFFHQHGCTTNDTNAKYNSRAAQLYKEKIKSLATQATRKHGTDLWTDGCGMPPASPQHKEEDFFASHASSKNTEWVLSEPEPAPLQQKASENIPESYEGGPEHGPSVDCLSTSPKATLENTSFIKKKPNQVKKGLGAKKGGLGAQKVSSQSFNEIEKQAQAVDKMKEQEDLHSSRKIEMEEPLVSSLRLAYRDLDIKTKEEKLNLSGKKKNELERLGMGFGSNRSGISHSVLSDMQTIEQETPTIGKPKKKYTDDVEDSYFSSSSSRYYDSSDLRSNTFSKWDDNSDPFWKKESNNRDVDVILTPKNTGFSDRPASRRKPEYEPSLSTDEAQKKFGNVKAISSDMYFGRQDHADYEARARLERLSGSSSISSADLFEDQKKQPAGYF", "length": 475, "header": "tr|A0A8V0YD81-1|A0A8V0YD81_CHICK Computationally mapped isoform of ADP-ribosylation factor GTPase-activating protein 3 OS=Gallus gallus OX=9031 GN=ARFGAP3 PE=1 SV=1 CANONICAL=A0A8V0YD99-1" }, "locus": { "chromosome": "1", "start_pos": 68481981, "end_pos": 68451969, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029171.1", "url": "https://www.ensembl.org/id/ENSGALT00010029171.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016915.1", "url": "https://www.ensembl.org/id/ENSGALP00010016915.1" } ] } }, { "isoform_ac": "A0A8V0YD99-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD99/entry#A0A8V0YD99-1", "sequence": { "sequence": "MCEPSKQDIGAIFKRLRSVPTNKVCFDCGSKNPSWASITYGVFLCIDCSGTHRSLGVHLSFIRSTELDSNWSWFQLRCMQVGGNANASAFFHQHGCTTNDTNAKYNSRAAQLYKEKIKSLATQATRKHGTDLWTDGCGMPPASPQHKEEDFFASHASSKNTEWVLSEPEPAPLQQKASENIPESYEGGPEHGPSVDCLSTSPKATLENTSFIKKKPNQVKKGLGAKKGGLGAQKVSSQSFNEIEKQAQAVDKMKEQEDLHSSRKIEMEEPLVSSLRLAYRDLDIKTKEEKLNLSGKKKNELERLGMGFGSNRSGISHSVLSDMQTIEQETPTIGKPKKKYTDDVEDSYFSSSSSRYYDSSDLRSNTFSKWDDNSDPFWKKESNNRDVDVILTPKNTGFSDRPASRRKPEYEPSLSTDEAQKKFGNVKAISSDMYFGRQDHADYEARARLERLSGSSSISSADLFEDQKKQPAGGYNITNVLPSAPDIAQFKQGVKSVAGKLSVLANGVMTSIQDRYGS", "length": 518, "header": "tr|A0A8V0YD99-1|A0A8V0YD99_CHICK Isoform 1 of ADP-ribosylation factor GTPase-activating protein 3 OS=Gallus gallus OX=9031 GN=ARFGAP3 PE=1 SV=1 CANONICAL=A0A8V0YD99-1" }, "locus": { "chromosome": "1", "start_pos": 68481981, "end_pos": 68449453, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029189.1", "url": "https://www.ensembl.org/id/ENSGALT00010029189.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016930.1", "url": "https://www.ensembl.org/id/ENSGALP00010016930.1" } ] } }, { "isoform_ac": "A0A8V0YGK9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD99/entry#A0A8V0YGK9-1", "sequence": { "sequence": "MTWVGRNAYPSAFFHQHGCTTNDTNAKYNSRAAQLYKEKIKSLATQATRKHGTDLWTDGCGMPPASPQHKEEDFFASHASSKNTEWVLSEPEPAPLQQKASENIPESYEGGPEHGPSVDCLSTSPKATLENTSFIKKKPNQVKKGLGAKKGGLGAQKVSSQSFNEIEKQAQAVDKMKEQEDLHSSRKIEMEEPLVSSLRLAYRDLDIKTKEEKLNLSGKKKNELERLGMGFGSNRSGISHSVLSDMQTIEQETPTIGKPKKKYTDDVEDSYFSSSSSRYYDSSDLRSNTFSKWDDNSDPFWKKESNNRDVDVILTPKNTGFSDRPASRRKPEYEPSLSTDEAQKKFGNVKAISSDMYFGRQDHADYEARARLERLSGSSSISSADLFEDQKKQPAGGYNITNVLPSAPDIAQFKQGVKSVAGKLSVLANGVMTSIQDRYGS", "length": 441, "header": "tr|A0A8V0YGK9-1|A0A8V0YGK9_CHICK Computationally mapped isoform of ADP ribosylation factor GTPase activating protein 3 OS=Gallus gallus OX=9031 GN=ARFGAP3 PE=1 SV=1 CANONICAL=A0A8V0YD99-1" }, "locus": { "chromosome": "1", "start_pos": 68474320, "end_pos": 68449453, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029141.1", "url": "https://www.ensembl.org/id/ENSGALT00010029141.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016893.1", "url": "https://www.ensembl.org/id/ENSGALP00010016893.1" } ] } }, { "isoform_ac": "A0A8V0YGM3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD99/entry#A0A8V0YGM3-1", "sequence": { "sequence": "MKVCFDCGSKNPSWASITYGVFLCIDCSGTHRSLGVHLSFIRSTELDSNWSWFQLRCMQVGGNANASAFFHQHGCTTNDTNAKYNSRAAQLYKEKIKSLATQATRKHGTDLWTDGCGMPPASPQHKEEDFFASHASSKNTEWVLSEPEPAPLQQKASENIPESYEGGPEHGPSVDCLSTSPKATLENTSFIKKKPNQVKKGLGAKKGGLGAQKVSSQSFNEIEKQAQAVDKMKEQEDLHSSRKIEMEEPLVSSLRLAYRDLDIKTKEEKLNLSGKKKNELERLGMGFGSNRSGISHSVLSDMQTIEQETPTIGKPKKKYTDDVEDSYFSSSSSRYYDSSDLRSNTFSKWDDNSDPFWKKESNNRDVDVILTPKNTGFSDRPASRRKPEYEPSLSTDEAQKKFGNVKAISSDMYFGRQDHADYEARARLERLSGSSSISSADLFEDQKKQPAGGYNITNVLPSAPDIAQFKQGVKSVAGKLSVLANGVMTSIQDRYGS", "length": 497, "header": "tr|A0A8V0YGM3-1|A0A8V0YGM3_CHICK Computationally mapped isoform of ADP-ribosylation factor GTPase-activating protein 3 OS=Gallus gallus OX=9031 GN=ARFGAP3 PE=1 SV=1 CANONICAL=A0A8V0YD99-1" }, "locus": { "chromosome": "1", "start_pos": 68478513, "end_pos": 68449453, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029163.1", "url": "https://www.ensembl.org/id/ENSGALT00010029163.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016909.1", "url": "https://www.ensembl.org/id/ENSGALP00010016909.1" } ] } }, { "isoform_ac": "A0A8V0YGP1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD99/entry#A0A8V0YGP1-1", "sequence": { "sequence": "MCEPSKQDIGAIFKRLRSVPTNKATVQGLLCSPAIEAVVLALVSIRNHFSFSQLPPFALLQNSLLKMKVCFDCGSKNPSWASITYGVFLCIDCSGTHRSLGVHLSFIRSTELDSNWSWFQLRCMQVGGNANASAFFHQHGCTTNDTNAKYNSRAAQLYKEKIKSLATQATRKHGTDLWTDGCGMPPASPQHKEEDFFASHASSKNTEWVLSEPEPAPLQQKASENIPESYEGGPEHGPSVDCLSTSPKATLENTSFIKKKPNQVKKGLGAKKGGLGAQKVSSQSFNEIEKQAQAVDKMKEQEDLHSSRKIEMEEPLVSSLRLAYRDLDIKTKEEKLNLSGKKKNELERLGMGFGSNRSGISHSVLSDMQTIEQETPTIGKPKKKYTDDVEDSYFSSSSSRYYDSSDLRSNTFSKWDDNSDPFWKKESNNRDVDVILTPKNTGFSDRPASRRKPEYEPSLSTDEAQKKFGNVKAISSDMYFGRQDHADYEARARLERLSGSSSISSADLFEDQKKQPAGGYNITNVLPSAPDIAQFKQGVKSVAGKLSVLANGVMTSIQDRYGS", "length": 563, "header": "tr|A0A8V0YGP1-1|A0A8V0YGP1_CHICK Computationally mapped isoform of ADP-ribosylation factor GTPase-activating protein 3 OS=Gallus gallus OX=9031 GN=ARFGAP3 PE=1 SV=1 CANONICAL=A0A8V0YD99-1" }, "locus": { "chromosome": "1", "start_pos": 68481981, "end_pos": 68449453, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029188.1", "url": "https://www.ensembl.org/id/ENSGALT00010029188.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016929.1", "url": "https://www.ensembl.org/id/ENSGALP00010016929.1" } ] } }, { "isoform_ac": "A0A8V0YLF1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD99/entry#A0A8V0YLF1-1", "sequence": { "sequence": "MKMHGIVGLDEHTWLEDLSWCCCIQTLGLPQVYLPAIGGFLFPSLALSLSLVRTASMAPLRDATQECELAANQVCFDCGSKNPSWASITYGVFLCIDCSGTHRSLGVHLSFIRSTELDSNWSWFQLRCMQVGGNANASAFFHQHGCTTNDTNAKYNSRAAQLYKEKIKSLATQATRKHGTDLWTDGCGMPPASPQHKEEDFFASHASSKNTEWVLSEPEPAPLQQKASENIPESYEGGPEHGPSVDCLSTSPKATLENTSFIKKKPNQVKKGLGAKKGGLGAQKVSSQSFNEIEKQAQAVDKMKEQEDLHSSRKIEMEEPLVSSLRLAYRDLDIKTKEEKLNLSGKKKNELERLGMGFGSNRSGISHSVLSDMQTIEQETPTIGKPKKKYTDDVEDSYFSSSSSRYYDSSDLRSNTFSKWDDNSDPFWKKESNNRDVDVILTPKNTGFSDRPASRRKPEYEPSLSTDEAQKKFGNVKAISSDMYFGRQDHADYEARARLERLSGSSSISSADLFEDQKKQPAGGYNITNVLPSAPDIAQFKQGVKSVAGKLSVLANGVMTSIQDRYGS", "length": 568, "header": "tr|A0A8V0YLF1-1|A0A8V0YLF1_CHICK Computationally mapped isoform of ADP-ribosylation factor GTPase-activating protein 3 OS=Gallus gallus OX=9031 GN=ARFGAP3 PE=1 SV=1 CANONICAL=A0A8V0YD99-1" }, "locus": { "chromosome": "1", "start_pos": 68480251, "end_pos": 68449453, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029179.1", "url": "https://www.ensembl.org/id/ENSGALT00010029179.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016922.1", "url": "https://www.ensembl.org/id/ENSGALP00010016922.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-6807878", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6807878", "resource": "Reactome", "description": "COPI-mediated anterograde transport" }, { "id": "R-GGA-6811434", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6811434", "resource": "Reactome", "description": "COPI-dependent Golgi-to-ER retrograde traffic" }, { "id": "R-GGA-9013408", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013408", "resource": "Reactome", "description": "RHOG GTPase cycle" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YD99", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD99" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YD99", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD99" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YD99", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD99" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YD99", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD99" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YD99", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD99" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YD99", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD99" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YD99", "url": 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"" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 208, "end_pos": 210 }, { "start_pos": 292, "end_pos": 294 }, { "start_pos": 311, "end_pos": 313 }, { "start_pos": 476, "end_pos": 478 }, { "start_pos": 70, "end_pos": 72 }, { "start_pos": 86, "end_pos": 88 }, { "start_pos": 99, "end_pos": 101 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YD67-1", "uniprot_ac": "A0A8V0YD67", "uniprot_id": "A0A8V0YD67_CHICK", "mass": { "chemical_mass": 29875.0, "monoisotopic_mass": 29875.0 }, "refseq": {}, "gene_names": [ { "name": "DRAM1", "type": "recommended", "evidence": [ { "id": "A0A8V0YD67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD67" } ] } ], "protein_names": [ { "name": "DNA damage regulated autophagy modulator 1", "type": "synonym", "evidence": [ { "id": "A0A8V0YD67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD67/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YD67", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD67" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "DRAM1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD67", "locus": { "chromosome": "1", "start_pos": 55537528, "end_pos": 55553135, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010011431", "url": "https://www.ensembl.org/id/ENSGALG00010011431" } ] } } ], "crossref": [ { "id": "A0A8V0YD67", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YD67", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000012761", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000012761", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "418095", "url": "https://www.ncbi.nlm.nih.gov/gene/418095", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR019402", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019402", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050911", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050911", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:418095", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418095", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QNRLALW", "url": "https://omabrowser.org/oma/group/QNRLALW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YD67", "url": "https://www.orthodb.org/?gene=A0A8V0YD67", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1BYC9", "url": "https://www.orthodb.org/?gene=E1BYC9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21324", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21324", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21324:SF11", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21324:SF11", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10277", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10277", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YD67", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD67", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YD67-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD67-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BYC9", "url": "https://www.uniprot.org/uniprotkb/E1BYC9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BYC9-1", "url": "https://www.uniprot.org/uniprotkb/E1BYC9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MWAPMPGAGQQREMLCFMPGVAAVPALLVGWSSAAFIISYVIAVLAGHVEPLVPYISDTGTKPPESGIFGFMINISALLGAITMYIRYLIIEKQNESLRFVRSSCNVFSLCIGLMGCTGMGIVATFQTTGRRHSFLLLLHAQHNELSVPSVHDIGALVAFGCGVVYITLQSIISYKSCPQWNTYFVCHIRMLISVISCISFIPMIVFASRISMTKIDWTPSEKDYTYHFMSAICEWTVAFGFVFFFLTFIKDFQRVTLRISTEIHEDS", "length": 268, "header": "tr|A0A8V0YD67-1|A0A8V0YD67_CHICK Isoform 1 of DNA damage regulated autophagy modulator 1 OS=Gallus gallus OX=9031 GN=DRAM1 PE=3 SV=1 CANONICAL=A0A8V0YD67-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YD67-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD67/entry#A0A8V0YD67-1", "sequence": { "sequence": "MWAPMPGAGQQREMLCFMPGVAAVPALLVGWSSAAFIISYVIAVLAGHVEPLVPYISDTGTKPPESGIFGFMINISALLGAITMYIRYLIIEKQNESLRFVRSSCNVFSLCIGLMGCTGMGIVATFQTTGRRHSFLLLLHAQHNELSVPSVHDIGALVAFGCGVVYITLQSIISYKSCPQWNTYFVCHIRMLISVISCISFIPMIVFASRISMTKIDWTPSEKDYTYHFMSAICEWTVAFGFVFFFLTFIKDFQRVTLRISTEIHEDS", "length": 268, "header": "tr|A0A8V0YD67-1|A0A8V0YD67_CHICK Isoform 1 of DNA damage regulated autophagy modulator 1 OS=Gallus gallus OX=9031 GN=DRAM1 PE=3 SV=1 CANONICAL=A0A8V0YD67-1" }, "locus": { "chromosome": "1", "start_pos": 55553001, "end_pos": 55539271, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027346.1", "url": "https://www.ensembl.org/id/ENSGALT00010027346.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015600.1", "url": "https://www.ensembl.org/id/ENSGALP00010015600.1" } ] } }, { "isoform_ac": "E1BYC9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD67/entry#E1BYC9-1", "sequence": { "sequence": "MWAPMPGAGQQREMLCFMPGVAAVPALLVGWSSAAFIISYVIAVLAGHVEPLVPYISDTGTKPPESGIFGFMINISALLGAITMYIRYLIIEKQNESLRFVRSSCNVFSLCIGLMGCTGMGIVATFQELSVPSVHDIGALVAFGCGVVYITLQSIISYKSCPQWNTYFVCHIRMLISVISCISFIPMIVFASRISMTKIDWTPSEKDYTYHFMSAICEWTVAFGFVFFFLTFIKDFQRVTLRISTEIHEDS", "length": 251, "header": "tr|E1BYC9-1|E1BYC9_CHICK Computationally mapped isoform of DNA damage regulated autophagy modulator 1 OS=Gallus gallus OX=9031 GN=DRAM1 PE=3 SV=2 CANONICAL=A0A8V0YD67-1" }, "locus": { "chromosome": "1", "start_pos": 55553001, "end_pos": 55539271, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027347.1", "url": "https://www.ensembl.org/id/ENSGALT00010027347.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015601.1", "url": "https://www.ensembl.org/id/ENSGALP00010015601.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:418095", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418095", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "F1MEI9-1", "protein_name": "DNA damage regulated autophagy modulator 1", "gene_name": "DRAM1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MLCFLRGMAFVPFLLVTWSSAAFIISYVVAVLSGHVNPFLPYISDTGTTPPESGIFGFMINFSAFLGAATMYTRYKIVEKQNQTSYFSTPVFNLVSLVLGLVGCIGMGIVANFQELAVPVVHDGGALLAFVCGVVYTLLQSVISYKSCPQWNSLSTCHVRMAISAVSCAAVIPMIACASLISITKLEWNPKEKDYVYHVVSAICEWTVAFGFIFYFLTFIHDFQSVTLRISTEINGDV", "length": 238 }, "evidence": [ { "id": "A0A8V0YD67", "url": "https://omabrowser.org/oma/group/A0A8V0YD67/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "O77262-1", "protein_name": "CWH43-like N-terminal domain-containing protein", "gene_name": "anon-WO0140519.169", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSQVYLLPVLTFLIFQVTFLGTYIFAVLEGHVVPTVPYISDAATYSPESCVFGQLINIGSVLLGITIYVRYRQVLQLYEHHPDLDGSVLRQNRLALWFGLVSCLGISFVGNFQETNVRIVHFIGAFCCFGCGTLYFWMQALISYLIFPMSGTRINAHLRLGMSVVCTILFILLAVTGVMSHILFKGQNPRKWYPSDGGWYFHVVSSISEWVIATVFSFFILSFTNEFRDVSLSHPQIALMSYSTTI", "length": 246 }, "evidence": [ { "id": "A0A8V0YD67", "url": "https://omabrowser.org/oma/group/A0A8V0YD67/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q8N682-1", "protein_name": "DNA damage-regulated autophagy modulator protein 1", "gene_name": "DRAM1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLCFLRGMAFVPFLLVTWSSAAFIISYVVAVLSGHVNPFLPYISDTGTTPPESGIFGFMINFSAFLGAATMYTRYKIVQKQNQTCYFSTPVFNLVSLVLGLVGCFGMGIVANFQELAVPVVHDGGALLAFVCGVVYTLLQSIISYKSCPQWNSLSTCHIRMVISAVSCAAVIPMIVCASLISITKLEWNPREKDYVYHVVSAICEWTVAFGFIFYFLTFIQDFQSVTLRISTEINGDI", "length": 238 }, "evidence": [ { "id": "A0A8V0YD67", "url": "https://omabrowser.org/oma/group/A0A8V0YD67/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9DC58-1", "protein_name": "DNA damage-regulated autophagy modulator protein 1", "gene_name": "Dram1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLCFLRGMAFVPFLLVTWSSAAFIISYVVAVLSGHVNPFLPYISDTGTTPPESGIFGFMINFSAFLGAATMYTRYKIVEKQNETCYFSTPVFNLVSLALGLVGCIGMGIVANFQELAVPVVHDGGALLAFVCGVVYTLLQSIISYKSCPQWNSLTTCHVRMAISAVSCAAVVPMIACASLISITKLEWNPKEKDYIYHVVSAICEWTVAFGFIFYFLTFIQDFQSVTLRISTEINDDF", "length": 238 }, "evidence": [ { "id": "A0A8V0YD67", "url": "https://omabrowser.org/oma/group/A0A8V0YD67/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "regulation of autophagy", "id": "GO:0010506", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010506", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YD67", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD67" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "lysosome", "id": "GO:0005764", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005764", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YD67", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD67" } ], "pmid": "" }, { "name": "endomembrane system", "id": "GO:0012505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0012505", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YD67", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD67" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 74, "end_pos": 76, "annotation": "n_glycosylation_sequon" }, { "start_pos": 95, "end_pos": 97, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YD67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD67" }, { "id": "PF10277", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10277" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CWH43-like N-terminal", "eco_id": "ECO_0000259", "start_pos": 22, "end_pos": 255, "start_aa": "Ala", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 74, "end_pos": 76 }, { "start_pos": 95, "end_pos": 97 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YD74-1", "uniprot_ac": "A0A8V0YD74", "uniprot_id": "A0A8V0YD74_CHICK", "mass": { "chemical_mass": 117243.0, "monoisotopic_mass": 117243.0 }, "refseq": { "ac": "NP_001385159", "name": "serine-rich coiled-coil domain-containing protein 2 isoform 2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001385159" }, "gene_names": [ { "name": "CCSER2", "type": "recommended", "evidence": [ { "id": "A0A8V0YD74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD74" } ] }, { "name": "CCSER2", "type": "synonym", "evidence": [ { "id": "NP_001385159", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001385159" } ] }, { "name": "FAM190B", "type": "synonym", "evidence": [ { "id": "NP_001385159", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001385159" } ] } ], "protein_names": [ { "name": "Coiled-coil serine rich protein 2", "type": "synonym", "evidence": [ { "id": "A0A8V0YD74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD74/entry#names_and_taxonomy" } ] }, { "name": "family with sequence similarity 190, member B", "type": "synonym", "evidence": [ { "id": "NP_001385159", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001385159" } ] }, { "name": "granule cell antiserum positive 14", "type": "synonym", "evidence": [ { "id": "NP_001385159", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001385159" } ] }, { "name": "serine-rich coiled-coil domain-containing protein 2 isoform 2", "type": "synonym", "evidence": [ { "id": "NP_001385159", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001385159" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: SRR13267659.127509.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992428 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000227.1. On Dec 10, 2021 this sequence version replaced XP_015143452.2.", "evidence": [ { "database": "RefSeq", "id": "NP_001385159", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001385159" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YD74", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD74" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CCSER2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD74", "locus": { "chromosome": "6", "start_pos": 1727016, "end_pos": 1658402, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010010267", "url": "https://www.ensembl.org/id/ENSGALG00010010267" } ] } } ], "crossref": [ { "id": "A0A8V0YD74", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YD74", "database": "AlphaFoldDB", "categories": [] }, { "id": "423606", "url": "https://www.ncbi.nlm.nih.gov/gene/423606", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR029627", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029627", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:423606", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423606", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "NECTKHT", "url": "https://omabrowser.org/oma/group/NECTKHT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y019", "url": "https://www.orthodb.org/?gene=A0A8V0Y019", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y4L3", "url": "https://www.orthodb.org/?gene=A0A8V0Y4L3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YD70", "url": "https://www.orthodb.org/?gene=A0A8V0YD70", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YD74", "url": "https://www.orthodb.org/?gene=A0A8V0YD74", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22461", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22461", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22461:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22461:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "NP_001385159", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001385159", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Y019", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y019", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y019-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y019-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y4L3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y4L3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y4L3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y4L3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YD70", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD70", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YD70-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD70-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YD74", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD74", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YD74-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD74-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEEKNQIRTSLVSRLPKYGTKTLGSALQPTSNGTAVNLAGNNGGKNFSKHNGTVNMSSFSFNWRKSNRYQLHDQNERETNSKHNCNDKLIDSEKYSQSQGALSNDMLRVGLNNTASVGSKTAKQNNMFVSSTEESNPKSLPGLSGSAKFTKGALSGRTSCSGLSAPKSHLNGFYGSRPMVGLQRPRANSNASRTSSGESLVHSTDNSKSSSCEKMVRSQSFSHSIQSSFLPTASLTRSHSFNKAVDLTRPYSQNLAVRTSQRSTLWTRNSRQLDVPNGNESVKYGFTRPYSSISSSCTKKPPLSNGSGSAPSFGYRLSRPSLLKPTSQRFAGNIIMDGGKSTTPDTYIVENSEISTNINRTIEKNSIIESNAQRTESVDGLHESMGKHGSNVMCMSDDGDEISISSLSSSEKNDLSEDFSDDFIDLEDPNKTIRVQQKESCIQELEHGSITSVEPFTSLKESGGSCCNADDWLDINVSAMDDNSESTKHTAESVISPEMNYRAGSSFELSPSDSSDGTYMWDEEGLEPIGSVHPCGSYESSEMNSIDILNNLDSCDLEDDDLMLDVDLPEDPPNDKDECENMSRYDRQDRNARQHQEGFWKRAPQQRWNAQDHYHLGHTEHYIHGKNDLNRGSNYLESSVGHFESYGAPNFYQAPRQLVSLPENTVMLDEMTLRHMVQDCTAVKTQLLKLKRLLHQNDENDSLQDISLSIPSSPEPQEPESTYFKTEDLLNEIRQLKDELKKKDETINQLEHQLASRCNCQKDSQKPTVAKCVYADKFTQTSWRRSSPQVLQPSSSLPSSTDLVQGKLIKMPYIEAPSEYSKHGVHENGNHQNQNAANVSLRNSLNDVNTSVNTQLSIKDENALYLENVKNKCTEDPGEVASDKEGTLLSCSRLQTSTRFDAREVRTEVAVKGQPSFTYQASRPKTSRIAKPPTALVPPTMAVLTRSANHSAASKEPELLLSSSSTQLQPTSGPDDLKGKQSQKVSKLRPPTISFIKSKQVSSQKSTSVSQEPQSTCLKTNIPKPQVQRKENVQTQNTALHSGDSLPSNRHSRLPKPKTH", "length": 1060, "header": "tr|A0A8V0YD74-1|A0A8V0YD74_CHICK Isoform 1 of Coiled-coil serine rich protein 2 OS=Gallus gallus OX=9031 GN=CCSER2 PE=3 SV=1 CANONICAL=A0A8V0YD74-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Y019-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD74/entry#A0A8V0Y019-1", "sequence": { "sequence": "MEEKNQIRTSLVSRLPKYGTKTLGSALQPTSNGTAVNLAGNNGGKNFSKHNGTVNMSSFSFNWRKSNRYQLHDQNERETNSKHNCNDKLIDSEKYSQSQGALSNDMLRVGLNNTASVGSKTAKQNNMFVSSTEESNPKSLPGLSGSAKFTKGALSGRTSCSGLSAPKSHLNGFYGSRPMVGLQRPRANSNASRTSSGESLVHSTDNSKSSSCEKMVRSQSFSHSIQSSFLPTASLTRSHSFNKAVDLTRPYSQNLAVRTSQRSTLWTRNSRQLDVPNGNESVKYGFTRPYSSISSSCTKKPPLSNGSGSAPSFGYRLSRPSLLKPTSQRFAGNIIMDGGKSTTPDTYIVENSEISTNINRTIEKNSIIESNAQRTESVDGLHESMGKHGSNVMCMSDDGDEISISSLSSSEKNDLSEDFSDDFIDLEDPNKTIRVQQKESCIQELEHGSITSVEPFTSLKESGGSCCNADDWLDINVSAMDDNSESTKHTAESVISPEMNYRAGSSFELSPSDSSDGTYMWDEEGLEPIGSVHPCGSYESSEMNSIDILNNLDSCDLEDDDLMLDVDLPEDPPNDKDECENMSRYDRQDRNARQHQEGFWKRAPQQRWNAQDHYHLGHTEHYIHGKNDLNRGSNYLESSVGHFESYGAPNFYQAPRQLVSLPENTVMLDEMTLRHMVQDCTAVKTQLLKLKRLLHQNDENDSLQDISLSIPSSPEPQEPESTYFKTEDLLNEIRQLKDELKKKDETINQLEHQLASRCNCQKDSQKPTVAKCVYADKFTQTSWRRSSGGYSAPSFSPWQGSFQGIPRTVPPHRRQRVEKLVHYFCDKACLKYYSLPAAFPVPQTSSREN", "length": 849, "header": "tr|A0A8V0Y019-1|A0A8V0Y019_CHICK Computationally mapped isoform of Coiled-coil serine rich protein 2 OS=Gallus gallus OX=9031 GN=CCSER2 PE=3 SV=1 CANONICAL=A0A8V0YD74-1" }, "locus": { "chromosome": "6", "start_pos": 1725039, "end_pos": 1673369, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010024502.1", "url": "https://www.ensembl.org/id/ENSGALT00010024502.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010013906.1", "url": "https://www.ensembl.org/id/ENSGALP00010013906.1" } ] } }, { "isoform_ac": "A0A8V0Y4L3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD74/entry#A0A8V0Y4L3-1", "sequence": { "sequence": "MHGILWTKHSLVQNDENDSLQDISLSIPSSPEPQEPESTYFKTEDLLNEIRQLKDELKKKDETINQLEHQLASRCNCQKDSQKPTVAKCVYADKFTQTSWRRSSPQVLQPSSSLPSSTDLVQGKLIKMPYIEAPSEYSKHGVHENGNHQNQNAANVSLRNSLNDVNTSVNTQLSIKDENALYLENVKNKCTEDPGEVASDKEGTLLSCSRLQTSTRFDAREVRTEVAVKGQPSFTYQASRPKTSRIAKPPTALVPPTMAVLTRSANHSAASKEPELLLSSSSTQLQPTSGPDDLKGKQSQKVSKLRPPTISFIKSKQVSSQKSTSVSQEPQSTCLKTNIPKPQVQRKENVQTQNTALHSGDSLPSNRHSRLPKPKTH", "length": 377, "header": "tr|A0A8V0Y4L3-1|A0A8V0Y4L3_CHICK Computationally mapped isoform of Coiled-coil serine rich protein 2 OS=Gallus gallus OX=9031 GN=CCSER2 PE=3 SV=1 CANONICAL=A0A8V0YD74-1" }, "locus": { "chromosome": "6", "start_pos": 1725797, "end_pos": 1698824, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010024480.1", "url": "https://www.ensembl.org/id/ENSGALT00010024480.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010013895.1", "url": "https://www.ensembl.org/id/ENSGALP00010013895.1" } ] } }, { "isoform_ac": "A0A8V0YD70-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD74/entry#A0A8V0YD70-1", "sequence": { "sequence": "MEEKNQIRTSLVSRLPKYGTKTLGSALQPTSNGTAVNLAGNNGGKNFSKHNGTVNMSSFSFNWRKSNRYQLHDQNERETNSKHNCNDKLIDSEKYSQSQGALSNDMLRVGLNNTASVGSKTAKQNNMFVSSTEESNPKSLPGLSGSAKFTKGALSGRTSCSGLSAPKSHLNGFYGSRPMVGLQRPRANSNASRTSSGESLVHSTDNSKSSSCEKMVRSQSFSHSIQSSFLPTASLTRSHSFNKAVDLTRPYSQNLAVRTSQRSTLWTRNSRQLDVPNGNESVKYGFTRPYSSISSSCTKKPPLSNGSGSAPSFGYRLSRPSLLKPTSQRFAGNIIMDGGKSTTPDTYIVENSEISTNINRTIEKNSIIESNAQRTESVDGLHESMGKHGSNVMCMSDDGDEISISSLSSSEKNDLSEDFSDDFIDLEDPNKTIRVQQKESCIQELEHGSITSVEPFTSLKESGGSCCNADDWLDINVSAMDDNSESTKHTAESVISPEMNYRAGSSFELSPSDSSDGTYMWDEEGLEPIGSVHPCGSYESSEMNSIDILNNLDSCDLEDDDLMLDVDLPEDPPNDKDECENMSRYDRQDRNARQHQEGFWKRAPQQRWNAQDHYHLGHTEHYIHGKNDLNRGSNYLESSVGHFESYGAPNFYQAPRQLVSLPENTVMLDEMTLRHMVQDCTAVKTQLLKLKRLLHQNDENDSLQDISLSIPSSPEPQEPESTYFKTEDLLNEIRQLKDELKKKDETINQLEHQLASRCNCQKDSQKPTVAKCVYADKFTQTSWRRSSGGYSAPSFSPWQGSFQGIPRTVPPHRRQTSSTTAFQQPSQFHRPRPGKTNKNAIYRGPQ", "length": 846, "header": "tr|A0A8V0YD70-1|A0A8V0YD74_CHICK Computationally mapped isoform of Coiled-coil serine rich protein 2 OS=Gallus gallus OX=9031 GN=CCSER2 PE=3 SV=1 CANONICAL=A0A8V0YD74-1" }, "locus": { "chromosome": "6", "start_pos": 1725070, "end_pos": 1673369, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010024494.1", "url": "https://www.ensembl.org/id/ENSGALT00010024494.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010013902.1", "url": "https://www.ensembl.org/id/ENSGALP00010013902.1" } ] } }, { "isoform_ac": "A0A8V0YD74-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD74/entry#A0A8V0YD74-1", "sequence": { "sequence": "MEEKNQIRTSLVSRLPKYGTKTLGSALQPTSNGTAVNLAGNNGGKNFSKHNGTVNMSSFSFNWRKSNRYQLHDQNERETNSKHNCNDKLIDSEKYSQSQGALSNDMLRVGLNNTASVGSKTAKQNNMFVSSTEESNPKSLPGLSGSAKFTKGALSGRTSCSGLSAPKSHLNGFYGSRPMVGLQRPRANSNASRTSSGESLVHSTDNSKSSSCEKMVRSQSFSHSIQSSFLPTASLTRSHSFNKAVDLTRPYSQNLAVRTSQRSTLWTRNSRQLDVPNGNESVKYGFTRPYSSISSSCTKKPPLSNGSGSAPSFGYRLSRPSLLKPTSQRFAGNIIMDGGKSTTPDTYIVENSEISTNINRTIEKNSIIESNAQRTESVDGLHESMGKHGSNVMCMSDDGDEISISSLSSSEKNDLSEDFSDDFIDLEDPNKTIRVQQKESCIQELEHGSITSVEPFTSLKESGGSCCNADDWLDINVSAMDDNSESTKHTAESVISPEMNYRAGSSFELSPSDSSDGTYMWDEEGLEPIGSVHPCGSYESSEMNSIDILNNLDSCDLEDDDLMLDVDLPEDPPNDKDECENMSRYDRQDRNARQHQEGFWKRAPQQRWNAQDHYHLGHTEHYIHGKNDLNRGSNYLESSVGHFESYGAPNFYQAPRQLVSLPENTVMLDEMTLRHMVQDCTAVKTQLLKLKRLLHQNDENDSLQDISLSIPSSPEPQEPESTYFKTEDLLNEIRQLKDELKKKDETINQLEHQLASRCNCQKDSQKPTVAKCVYADKFTQTSWRRSSPQVLQPSSSLPSSTDLVQGKLIKMPYIEAPSEYSKHGVHENGNHQNQNAANVSLRNSLNDVNTSVNTQLSIKDENALYLENVKNKCTEDPGEVASDKEGTLLSCSRLQTSTRFDAREVRTEVAVKGQPSFTYQASRPKTSRIAKPPTALVPPTMAVLTRSANHSAASKEPELLLSSSSTQLQPTSGPDDLKGKQSQKVSKLRPPTISFIKSKQVSSQKSTSVSQEPQSTCLKTNIPKPQVQRKENVQTQNTALHSGDSLPSNRHSRLPKPKTH", "length": 1060, "header": "tr|A0A8V0YD74-1|A0A8V0YD74_CHICK Isoform 1 of Coiled-coil serine rich protein 2 OS=Gallus gallus OX=9031 GN=CCSER2 PE=3 SV=1 CANONICAL=A0A8V0YD74-1" }, "locus": { "chromosome": "6", "start_pos": 1725797, "end_pos": 1673369, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010024504.1", "url": "https://www.ensembl.org/id/ENSGALT00010024504.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010013907.1", "url": "https://www.ensembl.org/id/ENSGALP00010013907.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:423606", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423606", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287B4Q0-1", "protein_name": "Coiled-coil serine rich protein 2", "gene_name": "CCSER2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEEKTQIKTFLGSRLPKYGTKSVRSTLQPMPNGKPVNLLGTSKSSNIKSFIKNNGSDCSSSHSFNWRTANKYQFSAQSPEEPNNTQSSHDKVIDPEKHVPTQGVFDKNGIKGGLKSISLFTSKLAKPTTMFVSSTEELNQKSLSGPSNLGKFTKGTLLGRTSYASVSAPKSQLNGFYGNRSTGSIQRPRANSCATRSSSGESLAQSLDNIKSLACEKMVRSQSFSHSIQNSFLPPSSITRSHSFNRAADLTKPYQNQQPPIRVPLRSSMLTRNSRQTEVLNGNEHLGYGFNRPYAAGGKKLALPNGPGVTSTLGYRMVHPSLLKSSRPPFSGTITVDGNKNSPADTCIEEDDTLVTKDRAANKDQELIENDSYRTENDQTVKHDAKIRYLSDDVDDISLSSLSSSDKNDLSEDFSDDFIDMEDSNRTRITPEEISLKEEKHENVPPKDIFDSPKENEKSFIKTEEWIDISVSDRSECSKHTSGNNLISPDTDYRAGSSFELSPSDSSDGTYMWDEEGLEPIGNVHPVGSYESSEMNSIDILNNLESCDLEDDDLMLDVDLPEDAPLENVECDNMNRFDRSDRNVRQSQEGFWKRPPQRWSGQEHYHLSHPDHYHHHGKSDLSRGSPYRESPLGHFESYGGTPFFQAQKMFVDVPENTVILDEMTLRHMVQDCTAVKTQLLKLKRLLHQHDGSGSLHDVQLSLPSSPEPEDSDQIYKNEDLLNEINQLKEEIKKKDEKIQLLEHQLATRCNCNQKSKEEKCTYADKYTQTPWRRIPGGYSAPSFSPWQGSFQGIPRTVPPHRRQTSSTTAFQQPSQTHRPRPGKTNKAATYRGPQ", "length": 834 }, "evidence": [ { "id": "A0A8V0YD74", "url": "https://omabrowser.org/oma/group/A0A8V0YD74/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A9J7KBU2-1", "protein_name": "Serine-rich coiled-coil domain-containing protein 2 isoform X1", "gene_name": "Ccser2", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MEEKAQIKTFLGSRLPKYGTKSVRSTLQPMPNGATVTLLGNSKNSNVKSYIKNNGSDCSLSHSFNWRQANKYQLGSQNTAELNSIQSAHGKLTDPEQHAPAPGTLDGNGIKGGLKSASLFTSKLARPSTMFLSSTEELNQKSFSGPSNLGKFTKGTLLGRTSYSSVNAKSHLNTFYRNQSPGNMQKPRVNSCATRSSSGESLAQSPDNTKSITCEKMVRSQSFSHSIQNSFLPPSSITRSHSFNRAVDLTKPYQNQQLPVRVPLRSGMLTRNSRQSEVLNGNEHLGFGFNRPYAAGGKKLALSNGPGVSSTLGYRMVHPSLLKSGRPPFPGTMTVDSNKNSPADMCVEEEAVVLAKDDSTGKDQELVENESYRTDNDQTMKHESKIRYLSDDVDDISLSSLSSSDKNDLSEDFSDDFIDLEDSNRTRITPEEITLKEEKCENRSSKDIFDSPKENGQIFSKADEWIDISVSDRSECTKHTSGNNLISPDTDYRAGSSFELSPSDSSDGTYMWDEEGLEPIGTVHPVGSYDSSEMNSIDILNNLESCDLEDDDLMLDVDLPEDAPLENVECDNMNRFDRADRNVRQSQDGFWKRAPQRWSGQEHYHLSHPDHYHHHGKSDLSRGSPYRETPLGHFESYGGTPFFQAQKMFVDVPDNTVILDEMTLRHMVQDCTAVKTQLLKLKRLLHQHDGSGSLNDVELSLPSSPEPEDDDQIYKNEDLLNEIKQLKEEIKKKDEKIQLLEHRLATRCNCHQKSKEEKCTYADKYTQTPWRRIPGGYSAPSFSPWQGSFQGMPRTVPPHRRQSQTSFCISRLGKKPQVLQPSSSLPRPTDHAQGKLIKPQHIEAHSENTVQGMCQSDAHPDGSFTHGLQQENSYGLKDCPFSSSPQFPMDVVKDVPSETNLSMTMNAQEPHHLAKNQPSDMEFVTTPPQTPSKSSTVNQTKKVRRSQSPQPKSLQPSKPSILSSVAHPPDSDSSPSRTSTSKKAPVITPCNSKHQPTSNQNNLANNLNLKVSKLRPPSGSFKQKQISNPQPEPQNFQAKTSIPRPLARSKELQNSLSNLHSGDYVASNRYSRLPKPKIN", "length": 1079 }, "evidence": [ { "id": "A0A8V0YD74", "url": "https://omabrowser.org/oma/group/A0A8V0YD74/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "D4A4E5-1", "protein_name": "Coiled-coil serine-rich protein 2", "gene_name": "Ccser2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEEKTQIKTFLGSKLPKYGMKSVRSTLQPMSNGATVTLLGTSKSSNVKSYIKNNGSDCSLSHSFNWRKTNKYQLGSQNTAELNNIQITHDKLIDTEQHAPAPGTLDGNGIEGGLNSTSLFTSKLARPSAMFVSSAEELSQKSFSGPSNLGKFTKGTLLGRTSYSSVSAKSHLNTFYGNRPPGNMQKPRMNSCASRSSSGESLAQSPDNAKSITCEKMVRSQSFSHSIQNAFLPPSSITRSHSFNRAVDLTKPYQNQQLPVRVPLRSGMLTRSARQSEVLNGNEHLGFGFNRPYAAGGKKLALSSGPGVSSTLVYRMGHPSLLKSSRPPFSGSMTVDSNKNPSADMCVEEEGVVSAKDSSTGKDQELIENESYRRDNDQTMKHDSKIRYLSDDVDDISLSSLSSSDKNDLSEDFSDDFIDLEDSNRTRITPEDITLKEEKHENGPSKDVFDSPKESEQIFSKADEWIDISVSDRSECTKHMSGNNLISPDTDYRAGSSFELSPSDSSDGTYMWDEEGLEPIGSVHPVGSYESSEMNSIDILNNLESCDLEDDDLMLDVDLPEDAPLENVDCDNMNRFDRTDRNVRQSQDGFWKRPSQRWSGQDHYHLSHPDHYHHHGKSDLSRGSPYRESPLGHFESYGGTPFFQAQKMFVDVPDNTVILDEMTLRHMVQDCTAVKTQLLKLKRLLHQHDGSGSLHDVQLSLPSSPEPEDGDQIYTNEDLLNEIKQLKEELKKKDEKIQLLEHQLATRCNCHQKSKEDRCAYADKFTQTPWRRSPGGYSAPSFSPWQGSFQGMPRTVPPHRRQTSSTTASQQPSQIYRPRPGKINKVTTYRGPQ", "length": 833 }, "evidence": [ { "id": "A0A8V0YD74", "url": "https://omabrowser.org/oma/group/A0A8V0YD74/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q3UHI0-1", "protein_name": "Serine-rich coiled-coil domain-containing protein 2", "gene_name": "Ccser2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEEKTQIKTFLGSKLPKYGMKSVRSTLQPMPNGATVTLLGTSKSSNVKSYIKNNGSDCSLSHSFNWRKTNKYQLGSQNTAELNNIQSTHDKLIEPEQHAPAPGTLDGHGIKGGLKSASLFTSKLARPSTMFVSSAEELSQKSFSGPSNLGKFTKGTLLGRTSYSSVNAKSHLNAFYGNRSSGNVQKPRVNSCASRSSSGESLAQSPDNAKSITCEKMVRSQSFSHSIQNVFLPPSSITRSHSFNRAVDLTKPYQNQQLPVRVPLRSGMLTRSSLQSEVLNGNEHVGFGFNRPYAAAGKKLALSNGPAVSSTLVYRMAHPPLLKSSRPPFSGPMTVDSNKNPPADMCVEEEGMVSAQDSSPGKDQELIENESYRRDNDQTGKNESKVRYLSDDVDDISLSSLSSSDKNDLSEDFSDDFIDLEDSNRTRITPEEMTLKEEKHESRPSKDIFDSPKESEQAFSKAEEWIDISVSDRSECTKHTSGNNLISPDTDYRAGSSFELSPSDSSDGTYMWDEEGLEPIGSVHPVGSYESSEMNSIDILNNLESCDLEDDDLMLDVDLPEDAPLENVECDNMNRFDRTDRNVRQSQDGFWKRPPQRWSGQDHYHLSHPGHYHHHGQSDLSRGSPYRESPLGHFESYGGTPFFQAQKMFVDVPDNTVILDEMTLRHMVQDCTAVKTQLLKLKRLLHQHDGSGSLHDVQLSLPSSPEPEDGDQIYKNEDLLNEITQLKEEIKKKDEKIQLLEQQLATRCNCQQKSKEEKCTYADKYTQTPWRRIPGGYCAPSFSPWQGSFQGMPRTVPPHRRQTSSTTAFQQPSQIYRPRPGKTNKATTYRGPQ", "length": 833 }, "evidence": [ { "id": "A0A8V0YD74", "url": "https://omabrowser.org/oma/group/A0A8V0YD74/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9H7U1-1", "protein_name": "Serine-rich coiled-coil domain-containing protein 2", "gene_name": "CCSER2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEEKTQIKTFLGSKLPKYGTKSVRSTLQPMPNGTPVNLLGTSKNSNVKSYIKNNGSDCPSSHSFNWRKANKYQLCAQGVEEPNNTQNSHDKIIDPEKRVPTQGMFDKNGIKGGLKSVSLFTSKLAKPSTMFVSSTEELNQKSFSGPSNLGKFTKGTLLGRTSYSSINTPKSQLNGFYGNRSAGSMQRPRANSCATRSSSGESLAQSPDSSKSINCEKMVRSQSFSHSIQNSFLPPSSITRSHSFNRAVDLTKPYQNQQLSIRVPLRSSMLTRNSRQPEVLNGNEHLGYGFNRPYAAGGKKLALPNGPGVTSTLGYRMVHPSLLKSSRSPFSGTMTVDGNKNSPADTCVEEDATVLAKDRAANKDQELIENESYRTKNNQTMKHDAKMRYLSDDVDDISLSSLSSSDKNDLSEDFSDDFIDIEDSNRTRITPEEMSLKEEKHENGPPQDMFDSPKENEKAFSKTDEWIDISVSDRSECTKHTSGNNLVSPDTDYRAGSSFELSPSDSSDGTYMWDEEGLEPIGNVHPVGSYESSEMNSIDILNNLESCDLEDDDLMLDVDLPEDAPLENVECDNMNRFDRPDRNVRQPQEGFWKRPPQRWSGQEHYHLSHPDHYHHHGKSDLSRGSPYRESPLGHFESYGGMPFFQAQKMFVDVPENTVILDEMTLRHMVQDCTAVKTQLLKLKRLLHQHDGSGSLHDIQLSLPSSPEPEDGDKVYKNEDLLNEIKQLKDEIKKKDEKIQLLELQLATQHICHQKCKEEKCTYADKYTQTPWRRIPGGYSAPSFSPWQGSFQGIPRTVPPHRRQTSSTTAFQQPSQTHRSHPGKTNKATTYRGPQ", "length": 834 }, "evidence": [ { "id": "A0A8V0YD74", "url": "https://omabrowser.org/oma/group/A0A8V0YD74/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "microtubule binding", "id": "GO:0008017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008017", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YD74", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD74" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "microtubule cytoskeleton", "id": "GO:0015630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015630", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YD74", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD74" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "microtubule bundle formation", "id": "GO:0001578", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001578", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YD74", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD74" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 112, "end_pos": 114, "annotation": "n_glycosylation_sequon" }, { "start_pos": 190, "end_pos": 192, "annotation": "n_glycosylation_sequon" }, { "start_pos": 279, "end_pos": 281, "annotation": "n_glycosylation_sequon" }, { "start_pos": 305, "end_pos": 307, "annotation": "n_glycosylation_sequon" }, { "start_pos": 32, "end_pos": 34, "annotation": "n_glycosylation_sequon" }, { "start_pos": 359, "end_pos": 361, "annotation": "n_glycosylation_sequon" }, { "start_pos": 430, "end_pos": 432, "annotation": "n_glycosylation_sequon" }, { "start_pos": 46, "end_pos": 48, "annotation": "n_glycosylation_sequon" }, { "start_pos": 476, "end_pos": 478, "annotation": "n_glycosylation_sequon" }, { "start_pos": 51, "end_pos": 53, "annotation": "n_glycosylation_sequon" }, { "start_pos": 55, "end_pos": 57, "annotation": "n_glycosylation_sequon" }, { "start_pos": 581, "end_pos": 583, "annotation": "n_glycosylation_sequon" }, { "start_pos": 700, "end_pos": 702, "annotation": "n_glycosylation_sequon" }, { "start_pos": 838, "end_pos": 840, "annotation": "n_glycosylation_sequon" }, { "start_pos": 849, "end_pos": 851, "annotation": "n_glycosylation_sequon" }, { "start_pos": 949, "end_pos": 951, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 112, "end_pos": 114 }, { "start_pos": 190, "end_pos": 192 }, { "start_pos": 279, "end_pos": 281 }, { "start_pos": 305, "end_pos": 307 }, { "start_pos": 32, "end_pos": 34 }, { "start_pos": 359, "end_pos": 361 }, { "start_pos": 430, "end_pos": 432 }, { "start_pos": 46, "end_pos": 48 }, { "start_pos": 476, "end_pos": 478 }, { "start_pos": 51, "end_pos": 53 }, { "start_pos": 55, "end_pos": 57 }, { "start_pos": 581, "end_pos": 583 }, { "start_pos": 700, "end_pos": 702 }, { "start_pos": 838, "end_pos": 840 }, { "start_pos": 849, "end_pos": 851 }, { "start_pos": 949, "end_pos": 951 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { 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{ "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YD77-1", "uniprot_ac": "A0A8V0YD77", "uniprot_id": "A0A8V0YD77_CHICK", "mass": { "chemical_mass": 114050.0, "monoisotopic_mass": 114050.0 }, "refseq": {}, "gene_names": [ { "name": "ZCCHC2", "type": "recommended", "evidence": [ { "id": "A0A8V0YD77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD77" } ] } ], "protein_names": [ { "name": "Zinc finger CCHC-type containing 2", "type": "synonym", "evidence": [ { "id": "A0A8V0YD77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD77/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YD77", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD77" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ZCCHC2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD77", "locus": { "chromosome": "2", "start_pos": 67875321, "end_pos": 67917253, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010011963", "url": "https://www.ensembl.org/id/ENSGALG00010011963" } ] } } ], "crossref": [ { "id": "A0A8V0YD77", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YD77", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR001878", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001878", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036871", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036871", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036875", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036875", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042793", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042793", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057327", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057327", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR058599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR058599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YD77", "url": "https://www.orthodb.org/?gene=A0A8V0YD77", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YD82", "url": "https://www.orthodb.org/?gene=A0A8V0YD82", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YK71", "url": "https://www.orthodb.org/?gene=A0A8V0YK71", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46939", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46939", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46939:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46939:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00098", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00098", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25479", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25479", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF26034", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF26034", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YD77", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD77", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YD77-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD77-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YD82", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD82", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YD82-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD82-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YK71", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK71", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YK71-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK71-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVGLLDLCNPLELRFLGSCLEDLARKDYHCLRDSEAKANGLSDPGQLGDFRDPAVRSKLIVYLALLGSENREAAGRLHRLLPQVDSILQSCPARRPRVGAAEEEGAEDEEEVVVVMDGAGENGQGPLPAAQGLGFGAQEELLLLFTMASLHPAFSFHQRVTLREHLERLRRALCGDQEEEEGFGRHRAQDDFSRSDCTSSNETSLLERTTAPHDGLPIASHRPQREAVHIEKITLKGVPRKRADKHLEYTFKVTWSDLSVTCVTKTHQELQEFLLKLPKELSSEAFDKTILRALNQGFQKREERRHADLEPIIRQLFSNTSQAFLQNQRVYNFFQSISSESLHTHSNLQPSLKTVKAPEHFKEDSSEASSQEEDVMQHAAVHKKHNGKSPVANSTSSAKCSSLDSLNIQHSEQNGVMDWRRKTCIVQQHPEHCTNILDQHTGEKRSLSAVSKKKGKPQLEKEKAKKADCRLNNRTNGVRVAASQHIRTGTAKDLNLDTGSGHDTCGETSSESYSSPSSPRHDGRESFDSEEEKDRDTDSNSEDSGNQNATRFTGYSAVGSSNMNKSSAQISSANNENGSLSEDPLNAKFQHISFMPALHCVMHSAAQKPEAVVPPPISADGKTMGMLVTTPVAVSPVRESANSPPGGMGPVTSGEPEKRLELMASPLPVPSTFLPHSVQPGSPALHLAIHRLKMPSPQGSSESCTVNGPQQPTGNLSIGSPNTAFIPVHNPGSFPGSPVPTTDPIAKPASQVVGLNQMVPHIEGNPAAIPQPTNLKVVLPAAGLSTAAPPPPPASYALPGSPHATSVLPNQNTNVLNTVATSSPPQSAGLGVGQIQSSVPPAIPTHTPGPAPSPSPALTHSTAQSDSTSYINAVGNNNTNGTMLPPQQLGSGPCGSCGRRCSCGTNGSLQINSYFYHNPLHGQVYRVPSFFTLPSLCNGSYLNQAHQSNGTQLPFFLPQSPYANGLMHDPVMGSQANYGMQQMAGFGRFYPVYPAPNVVANTNGSGPKKNGNVSCYNCGVSGHYAQDCKQSSMEASQQGTYRLRYAPPPPPSNDTLDSAD", "length": 1060, "header": "tr|A0A8V0YD77-1|A0A8V0YD77_CHICK Isoform 1 of Zinc finger CCHC-type containing 2 OS=Gallus gallus OX=9031 GN=ZCCHC2 PE=4 SV=1 CANONICAL=A0A8V0YD77-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YD77-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD77/entry#A0A8V0YD77-1", "sequence": { "sequence": "MVGLLDLCNPLELRFLGSCLEDLARKDYHCLRDSEAKANGLSDPGQLGDFRDPAVRSKLIVYLALLGSENREAAGRLHRLLPQVDSILQSCPARRPRVGAAEEEGAEDEEEVVVVMDGAGENGQGPLPAAQGLGFGAQEELLLLFTMASLHPAFSFHQRVTLREHLERLRRALCGDQEEEEGFGRHRAQDDFSRSDCTSSNETSLLERTTAPHDGLPIASHRPQREAVHIEKITLKGVPRKRADKHLEYTFKVTWSDLSVTCVTKTHQELQEFLLKLPKELSSEAFDKTILRALNQGFQKREERRHADLEPIIRQLFSNTSQAFLQNQRVYNFFQSISSESLHTHSNLQPSLKTVKAPEHFKEDSSEASSQEEDVMQHAAVHKKHNGKSPVANSTSSAKCSSLDSLNIQHSEQNGVMDWRRKTCIVQQHPEHCTNILDQHTGEKRSLSAVSKKKGKPQLEKEKAKKADCRLNNRTNGVRVAASQHIRTGTAKDLNLDTGSGHDTCGETSSESYSSPSSPRHDGRESFDSEEEKDRDTDSNSEDSGNQNATRFTGYSAVGSSNMNKSSAQISSANNENGSLSEDPLNAKFQHISFMPALHCVMHSAAQKPEAVVPPPISADGKTMGMLVTTPVAVSPVRESANSPPGGMGPVTSGEPEKRLELMASPLPVPSTFLPHSVQPGSPALHLAIHRLKMPSPQGSSESCTVNGPQQPTGNLSIGSPNTAFIPVHNPGSFPGSPVPTTDPIAKPASQVVGLNQMVPHIEGNPAAIPQPTNLKVVLPAAGLSTAAPPPPPASYALPGSPHATSVLPNQNTNVLNTVATSSPPQSAGLGVGQIQSSVPPAIPTHTPGPAPSPSPALTHSTAQSDSTSYINAVGNNNTNGTMLPPQQLGSGPCGSCGRRCSCGTNGSLQINSYFYHNPLHGQVYRVPSFFTLPSLCNGSYLNQAHQSNGTQLPFFLPQSPYANGLMHDPVMGSQANYGMQQMAGFGRFYPVYPAPNVVANTNGSGPKKNGNVSCYNCGVSGHYAQDCKQSSMEASQQGTYRLRYAPPPPPSNDTLDSAD", "length": 1060, "header": "tr|A0A8V0YD77-1|A0A8V0YD77_CHICK Isoform 1 of Zinc finger CCHC-type containing 2 OS=Gallus gallus OX=9031 GN=ZCCHC2 PE=4 SV=1 CANONICAL=A0A8V0YD77-1" }, "locus": { "chromosome": "2", "start_pos": 67917155, "end_pos": 67877240, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028634.1", "url": "https://www.ensembl.org/id/ENSGALT00010028634.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016450.1", "url": "https://www.ensembl.org/id/ENSGALP00010016450.1" } ] } }, { "isoform_ac": "A0A8V0YD82-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD77/entry#A0A8V0YD82-1", "sequence": { "sequence": "MVGLLDLCNPLELRFLGSCLEDLARKDYHCLRDSEAKANGLSDPGQLGDFRDPAVRSKLIVYLALLGSENREAAGRLHRLLPQVDSILQSCPARRPRVGAAEEEGAEDEEEVVVVMDGAGENGQGPLPAAQGLGFGAQEELLLLFTMASLHPAFSFHQRVTLREHLERLRRALCGDQEEEEGFGRHRAQDDFSRSDCTSSNETSLLERTTAPHDGLPIASHRPQREAVHIEKITLKGVPRKRADKHLEYTFKLPKELSSEAFDKTILRALNQGFQKREERRHADLEPIIRQLFSNTSQAFLQNQRVYNFFQSISSESLHTHSNLQPSLKTVKAPEHFKEDSSEASSQEEDVMQHAAVHKKHNGKSPVANSTSSAKCSSLDSLNIQHSEQNGVMDWRRKTCIVQQHPEHCTNILDQHTGEKRSLSAVSKKKGKPQLEKEKAKKADCRLNNRTNGVRVAASQHIRTGTAKDLNLDTGSGHDTCGETSSESYSSPSSPRHDGRESFDSEEEKDRDTDSNSEDSGNQNATRFTGYSAVGSSNMNKSSAQISSANNENGSLSEDPLNAKFQHISFMPALHCVMHSAAQKPEAVVPPPISADGKTMGMLVTTPVAVSPVRESANSPPGGMGPVTSGEPEKRLELMASPLPVPSTFLPHSVQPGSPALHLAIHRLKMPSPQGSSESCTVNGPQQPTGNLSIGSPNTAFIPVHNPGSFPGSPVPTTDPIAKPASQVVGLNQMVPHIEGNPAAIPQPTNLKVVLPAAGLSTAAPPPPPASYALPGSPHATSVLPNQNTNVLNTVATSSPPQSAGLGVGQIQSSVPPAIPTHTPGPAPSPSPALTHSTAQSDSTSYINAVGNNNTNGTMLPPQQLGSGPCGSCGRRCSCGTNGSLQINSYFYHNPLHGQVYRVPSFFTLPSLCNGSYLNQAHQSNGTQLPFFLPQSPYANGLMHDPVMGSQANYGMQQMAGFGRFYPVYPAPNVVANTNGSGPKKNGNVSCYNCGVSGHYAQDCKQSSMEASQQGTYRLRYAPPPPPSNDTLDSAD", "length": 1036, "header": "tr|A0A8V0YD82-1|A0A8V0YD82_CHICK Computationally mapped isoform of Zinc finger CCHC-type containing 2 OS=Gallus gallus OX=9031 GN=ZCCHC2 PE=4 SV=1 CANONICAL=A0A8V0YD77-1" }, "locus": { "chromosome": "2", "start_pos": 67917155, "end_pos": 67877240, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028640.1", "url": "https://www.ensembl.org/id/ENSGALT00010028640.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016455.1", "url": "https://www.ensembl.org/id/ENSGALP00010016455.1" } ] } }, { "isoform_ac": "A0A8V0YK71-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD77/entry#A0A8V0YK71-1", "sequence": { "sequence": "MVGLLDLCNPLELRFLGSCLEDLARKDYHCLRDSEAKANGLSDPGQLGDFRDPAVRSKLIVYLALLGSENREAAGRLHRLLPQVDSILQSCPARRPRVGAAEEEGAEDEEEVVVVMDGAGENGQGPLPAAQGLGFGAQEELLLLFTMASLHPAFSFHQRVTLREHLERLRRALCGDQEEEEGFGRHRAQDDFSRSDCTSSNETSLLERTTAPHDGLPIASHRPQREAVHIEKITLKGVPRKRADKHLEYTFKVTWSDLSVTCVTKTHQELQEFLLKLPKELSSEAFDKTILRALNQGFQKREERRHADLEPIIRQLFSNTSQAFLQNQRVYNFFQSISSESLHTHNVMQHAAVHKKHNGKSPVANSTSSAKCSSLDSLNIQHSEQNGVMDWRRKTCIVQQHPEHCTNILDQHTGEKRSLSAVSKKKGKPQLEKEKAKKADCRLNNRTNGVRVAASQHIRTGTAKDLNLDTGSGHDTCGETSSESYSSPSSPRHDGRESFDSEEEKDRDTDSNSEDSGNQNATRFTGYSAVGSSNMNKSSAQISSANNENGSLSEDPLNAKFQHISFMPALHCVMHSAAQKPEAVVPPPISADGKTMGMLVTTPVAVSPVRESANSPPGGMGPVTSGEPEKRLELMASPLPVPSTFLPHSVQPGSPALHLAIHRLKMPSPQGSSESCTVNGPQQPTGNLSIGSPNTAFIPVHNPGSFPGSPVPTTDPIAKPASQVVGLNQMVPHIEGNPAAIPQPTNLKVVLPAAGLSTAAPPPPPASYALPGSPHATSVLPNQNTNVLNTVATSSPPQSAGLGVGQIQSSVPPAIPTHTPGPAPSPSPALTHSTAQSDSTSYINAVGNNNTNGTMLPPQQLGSGPCGSCGRRCSCGTNGSLQINSYFYHNPLHGQVYRVPSFFTLPSLCNGSYLNQAHQSNGTQLPFFLPQSPYANGLMHDPVMGSQANYGMQQMAGFGRFYPVYPAPNVVANTNGSGPKKNGNVSCYNCGVSGHYAQDCKQSSMEASQQGTYRLRYAPPPPPSNDTLDSAD", "length": 1032, "header": "tr|A0A8V0YK71-1|A0A8V0YK71_CHICK Computationally mapped isoform of Zinc finger CCHC-type containing 2 OS=Gallus gallus OX=9031 GN=ZCCHC2 PE=4 SV=1 CANONICAL=A0A8V0YD77-1" }, "locus": { "chromosome": "2", "start_pos": 67917155, "end_pos": 67877240, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028645.1", "url": "https://www.ensembl.org/id/ENSGALT00010028645.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016459.1", "url": "https://www.ensembl.org/id/ENSGALP00010016459.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YD77", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD77" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YD77", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD77" } ], "pmid": "" }, { "name": "nucleic acid binding", "id": "GO:0003676", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003676", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YD77", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD77" } ], "pmid": "" }, { "name": "phosphatidylinositol binding", "id": "GO:0035091", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035091", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YD77", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD77" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1003, "end_pos": 1005, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1012, "end_pos": 1014, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1053, "end_pos": 1055, "annotation": "n_glycosylation_sequon" }, { "start_pos": 201, "end_pos": 203, "annotation": "n_glycosylation_sequon" }, { "start_pos": 319, "end_pos": 321, "annotation": "n_glycosylation_sequon" }, { "start_pos": 393, "end_pos": 395, "annotation": "n_glycosylation_sequon" }, { "start_pos": 473, "end_pos": 475, "annotation": "n_glycosylation_sequon" }, { "start_pos": 548, "end_pos": 550, "annotation": "n_glycosylation_sequon" }, { "start_pos": 564, "end_pos": 566, "annotation": "n_glycosylation_sequon" }, { "start_pos": 577, "end_pos": 579, "annotation": "n_glycosylation_sequon" }, { "start_pos": 715, "end_pos": 717, "annotation": "n_glycosylation_sequon" }, { "start_pos": 877, "end_pos": 879, "annotation": "n_glycosylation_sequon" }, { "start_pos": 880, "end_pos": 882, "annotation": "n_glycosylation_sequon" }, { "start_pos": 906, "end_pos": 908, "annotation": "n_glycosylation_sequon" }, { "start_pos": 938, "end_pos": 940, "annotation": "n_glycosylation_sequon" }, { "start_pos": 949, "end_pos": 951, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YD77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD77" }, { "id": "PS50158", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50158" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CCHC-type", "eco_id": "ECO_0000259", "start_pos": 1015, "end_pos": 1030, "start_aa": "Cys", "end_aa": "Gln", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1003, "end_pos": 1005 }, { "start_pos": 1012, "end_pos": 1014 }, { "start_pos": 1053, "end_pos": 1055 }, { "start_pos": 201, "end_pos": 203 }, { "start_pos": 319, "end_pos": 321 }, { "start_pos": 393, "end_pos": 395 }, { "start_pos": 473, "end_pos": 475 }, { "start_pos": 548, "end_pos": 550 }, { "start_pos": 564, "end_pos": 566 }, { "start_pos": 577, "end_pos": 579 }, { "start_pos": 715, "end_pos": 717 }, { "start_pos": 877, "end_pos": 879 }, { "start_pos": 880, "end_pos": 882 }, { "start_pos": 906, "end_pos": 908 }, { "start_pos": 938, "end_pos": 940 }, { "start_pos": 949, "end_pos": 951 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": 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mapped isoform of Centriole, cilia and spindle associated protein OS=Gallus gallus OX=9031 GN=CCSAP PE=4 SV=1 CANONICAL=A0A8V0YD79-1" }, "locus": { "chromosome": "3", "start_pos": 39668925, "end_pos": 39660647, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010024517.1", "url": "https://www.ensembl.org/id/ENSGALT00010024517.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010013911.1", "url": "https://www.ensembl.org/id/ENSGALP00010013911.1" } ] } }, { "isoform_ac": "A0A8V0YD79-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD79/entry#A0A8V0YD79-1", "sequence": { "sequence": "MESPPALTLSLGLGAARATSSPHLTHKALPAQPGPPVATDSYRFSVPWEPRGLSLPGLLAPATLQELPYLPPLRWPWQEGCTWFGADPYYHCSRDSTAGRKDDFQLNLLSSTASKGNFCRKRQYLVREVPVQPYVPQAEWLGLAGRAGSHPFLKRQTEEKEKERQDQEKHQKEEQEKTVEHTSTKEADKTSTKEADKTSRTGRRPSQSALSSRNDRRSAKSPQKTDAPKENKHPFALYGWGERQTDTGSQKTHNVCASASVNEIHESALRAKNRRQVEKRKLSQRRVRSAEAEKAWRIKPSPPDNPWMTEYMRCYSARAR", "length": 320, "header": "tr|A0A8V0YD79-1|A0A8V0YD79_CHICK Isoform 1 of Centriole, cilia and spindle associated protein OS=Gallus gallus OX=9031 GN=CCSAP PE=4 SV=1 CANONICAL=A0A8V0YD79-1" }, "locus": { "chromosome": "3", "start_pos": 39679747, "end_pos": 39660647, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010024520.1", "url": "https://www.ensembl.org/id/ENSGALT00010024520.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010013912.1", "url": "https://www.ensembl.org/id/ENSGALP00010013912.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 9, "go_terms": [ { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YD79", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD79" } ], "pmid": "" }, { "name": 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"https://www.ebi.ac.uk/QuickGO/term/GO:0036064", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YD79", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD79" } ], "pmid": "" }, { "name": "mitotic spindle astral microtubule", "id": "GO:0061673", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061673", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YD79", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD79" } ], "pmid": "" }, { "name": "ciliary transition zone", "id": "GO:0035869", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035869", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YD79", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD79" } ], "pmid": "" }, { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YD79", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD79" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "microtubule binding", "id": "GO:0008017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008017", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YD79", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD79" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "regulation of mitotic spindle assembly", "id": "GO:1901673", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901673", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YD79", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD79" } ], "pmid": "" }, { "name": "mitotic spindle microtubule depolymerization", "id": "GO:1990755", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990755", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YD79", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD79" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], 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"isoform_ac": "A0A8V0YD92-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD92/entry#A0A8V0YD92-1", "sequence": { "sequence": "MAVPESDARLAQEKEEESEEESEILEESPCGRWQKRREQVNQGNMPGIQSTFLAMDTEEGVEVVWNELLFTDKKAFKAHEEKIKTMFEQLVLVDHPNIVKLHKYWLDVKDSKARVIFITEYVSSGSLKQFLKKTKKNHKAMNARRCRRNVALIVAELCTWGEQLCPHSSGLSVGWWFRTRSQHDCRSLSEKVTAQKRSAACEVLQ", "length": 205, "header": "tr|A0A8V0YD92-1|A0A8V0YD92_CHICK Isoform 1 of Nuclear receptor binding protein 2 OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0YD92-1" }, "locus": { "chromosome": "2", "start_pos": 149084281, "end_pos": 149068020, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010024546.1", "url": "https://www.ensembl.org/id/ENSGALT00010024546.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010013927.1", "url": "https://www.ensembl.org/id/ENSGALP00010013927.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "protein kinase activity", "id": "GO:0004672", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004672", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YD92", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD92" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YD92", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD92" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YD92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD92" }, { "id": "PF07714", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07714" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Serine-threonine/tyrosine-protein kinase catalytic", "eco_id": "ECO_0000259", "start_pos": 73, "end_pos": 151, "start_aa": "Lys", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YDA3-1", "uniprot_ac": "A0A8V0YDA3", "uniprot_id": "A0A8V0YDA3_CHICK", "mass": { "chemical_mass": 117346.0, "monoisotopic_mass": 117346.0 }, "refseq": {}, "gene_names": [ { "name": "IPO11", "type": "recommended", "evidence": [ { "id": "A0A8V0YDA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDA3" } ] } ], "protein_names": [ { "name": "Importin-11", "type": "recommended", "evidence": [ { "id": "A0A8V0YDA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDA3/entry#names_and_taxonomy" } ] }, { "name": "Ran-binding protein 11", "type": "synonym", "evidence": [ { "id": "A0A8V0YDA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDA3/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YDA3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDA3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "IPO11", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDA3", "locus": { "chromosome": "Z", "start_pos": 20114933, "end_pos": 20041124, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010011972", "url": "https://www.ensembl.org/id/ENSGALG00010011972" } ] } } ], "crossref": [ { "id": "A0A8V0YDA3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YDA3", "database": "AlphaFoldDB", "categories": [] }, { "id": "769679", "url": "https://www.ncbi.nlm.nih.gov/gene/769679", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001494", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001494", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR058669", "url": "https://www.ebi.ac.uk/interpro/entry/IPR058669", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:769679", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:769679", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "SFHYVFH", "url": "https://omabrowser.org/oma/group/SFHYVFH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y728", "url": "https://www.orthodb.org/?gene=A0A8V0Y728", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YBZ9", "url": "https://www.orthodb.org/?gene=A0A8V0YBZ9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YC04", "url": "https://www.orthodb.org/?gene=A0A8V0YC04", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YDA3", "url": "https://www.orthodb.org/?gene=A0A8V0YDA3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10997", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10997", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10997:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10997:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03810", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03810", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25758", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25758", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0Y728", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y728", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y728-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y728-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YBZ9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBZ9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YBZ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBZ9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YC04", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC04", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YC04-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC04-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YDA3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDA3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YDA3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDA3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTFIGKTTERCACVNELRLVVTSWFYLLAAEVLVAVCSVCCASHKIFMDLNSASSIVLQVLTQATSQDTAVLKPAEEQLKQWETQPGFYSVLLNIFTNHALDVNVRWLAVLYFKNGIDRYWRRVAPHALSEEEKTTLRAGLIANFNEPVNQIATQISVLIAKVARVDCPRQWPELIPTLLESVKVQDDLRQHRALLTFYHVTKTLASKRLAADRKLFYDLASGIYSFACSLWNHHTDTFLQQACTGNEAAASNSLERTLLSLKVLRKLTVHGFVEPHRSVEVMGFLHALFERLKQFLECSRNIRTGNVCRDRLEKTIILFTKVLLDFLDQHPFSFTPLIQRSLEFAVSYVFTEAGEGVVFERFIVQCMNLIKMIVKNYAYKPSKYIEDSSPETLEAHKIKTAFFTYPTLMEICRRLVTHYFLLTEEELTMWEEDPEGFTVEETGGDSWKYSLRPCTEVLFIDIFHEYNQTLTPVLLEMVHSLQGTTNLEDTSAILIKDAVYNAVGLAAYELFDSVDFDQWFKNQLLAELQVSHNRYKPIRRRVIWLIGQWISVKFKSDLRPMLYEAIRNLLQDQDLVVRIETATTLKLTVDDFEFRTDQFLPYLESMFTLLFQLLQEVTECDTKMHVLHVLSCVNERVNVQIRPYVGCLVQYLPLLWKQSEEHNMLRCAILTTLIHLVQGLGAESKNLYPFLLPIIQLSTDVSQPPHVYLLEDGLELWLVTLENSPCLTPELLRIFQNMSALLELSSENLKNCFKIINAYVFLSSTEFLQTYAVDLCRSFCELLKDITTEGQVQALKVVENVLKVNPILGPQMFQPLLPSVFRGIIDGERYPMLMSTYLGVIGRVLLQNTSFFSLLLNQMACESGQELDQILGNMIEMWVDRMDNITQPERRKLSALALISLLPSLNSVIQDKFCGIIHVTLEGLYDVMTEDPETGTYKDCLLLSHFEEPKVTEDEEPPTEQDKRKKLLALKDPVHTVSLQQFVYEKLKAQQELLGEQGFHALMETVDTEVVAQLQEFLQGF", "length": 1022, "header": "tr|A0A8V0YDA3-1|A0A8V0YDA3_CHICK Isoform 1 of Importin-11 OS=Gallus gallus OX=9031 GN=IPO11 PE=1 SV=1 CANONICAL=A0A8V0YDA3-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Y728-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDA3/entry#A0A8V0Y728-1", "sequence": { "sequence": "MDLNSASSIVLQVLTQATSQDTAVLKPAEEQLKQWETQPGFYSVLLNIFTNHALDVNVRWLAVLYFKNGIDRYWRRVAPHALSEEEKTTLRAGLIANFNEPVNQIATQISVLIAKVARVDCPRQWPELIPTLLESVKVQDDLRQHRALLTFYHVTKTLASKRLAADRKLFYDLASGIYSFACSLWNHHTDTFLQQACTGNEAAASNSLERTLLSLKVLRKLTVHGFVEPHRSVEVMGFLHALFERLKQFLECSRNIRTGNVCRDRLEKTIILFTKVLLDFLDQHPFSFTPLIQRSLEFAVSYVFTEAGEGVVFERFIVQCMNLIKMIVKNYAYKPSKYIEDSSPETLEAHKIKTAFFTYPTLMEICRRLVTHYFLLTEEELTMWEEDPEGFTVEETGGDSWKYSLRPCTEVLFIDIFHEYNQTLTPVLLEMVHSLQGTTNLEDTSAILIKDAVYNAVGLAAYELFDSVDFDQWFKNQLLAELQVSHNRYKPIRRRVIWLIGQWISVKFKSDLRPMLYEAIRNLLQDQDLVEVTECDTKMHVLHVLSCVNERVNVQIRPYVGCLVQYLPLLWKQSEEHNMLRCAILTTLIHLVQGLGAESKNLYPFLLPIIQLSTDVSQPPHVYLLEDGLELWLVTLENSPCLTPELLRIFQNMSALLELSSENLKNCFKIINAYVFLSSTEFLQTYAVDLCRSFCELLKDITTEGQVQALKVVENVLKVNPILGPQMFQPLLPSVFRGIIDGERYPMLMSTYLGVIGRVLLQNTSFFSLLLNQMACESGQELDQILGNMIEMWVDRMDNITQPERRKLSALALISLLPSLNSVIQDKFCGIIHVTLEGLYDVMTEDPETGTYKDCLLLSHFEEPKVTEDEEPPTEQDKRKKLLALKDPVHTVSLQQFVYEKLKAQQELLGEQGFHALMETVDTEVVAQLQEFLQGF", "length": 936, "header": "tr|A0A8V0Y728-1|A0A8V0Y728_CHICK Computationally mapped isoform of Importin-11 OS=Gallus gallus OX=9031 GN=IPO11 PE=1 SV=1 CANONICAL=A0A8V0YDA3-1" }, "locus": { "chromosome": "Z", "start_pos": 20114741, "end_pos": 20049175, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028656.1", "url": "https://www.ensembl.org/id/ENSGALT00010028656.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016468.1", "url": "https://www.ensembl.org/id/ENSGALP00010016468.1" } ] } }, { "isoform_ac": "A0A8V0YBZ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDA3/entry#A0A8V0YBZ9-1", "sequence": { "sequence": "MDLNSASSIVLQVLTQATSQDTAVLKPAEEQLKQWETQPGFYSVLLNIFTNHALDVNVRWLAVLYFKNGIDRYWRRVAPQETKQFFLWCNSAQSALSEEEKTTLRAGLIANFNEPVNQIATQISVLIAKVARVDCPRQWPELIPTLLESVKVQDDLRQHRALLTFYHVTKTLASKRLAADRKLFYDLASGIYSFACSLWNHHTDTFLQQACTGNEAAASNSLERTLLSLKVLRKLTVHGFVEPHRSVEVMGFLHALFERLKQFLECSRNIRTGNVCRDRLEKTIILFTKVLLDFLDQHPFSFTPLIQRSLEFAVSYVFTEAGEGVVFERFIVQCMNLIKMIVKNYAYKPSKYIEDSSPETLEAHKIKTAFFTYPTLMEICRRLVTHYFLLTEEELTMWEEDPEGFTVEETGGDSWKYSLRPCTEVLFIDIFHEYNQTLTPVLLEMVHSLQGTTNLEDTSAILIKDAVYNAVGLAAYELFDSVDFDQWFKNQLLAELQVSHNRYKPIRRRVIWLIGQWISVKFKSDLRPMLYEAIRNLLQDQDLVVRIETATTLKLTVDDFEFRTDQFLPYLESMFTLLFQLLQEVTECDTKMHVLHVLSCVNERVNVQIRPYVGCLVQYLPLLWKQSEEHNMLRCAILTTLIHLVQGLGAESKNLYPFLLPIIQLSTDVSQPPHVYLLEDGLELWLVTLENSPCLTPELLRIFQNMSALLELSSENLKNCFKIINAYVFLSSTEFLQTYAVDLCRSFCELLKDITTEGQVQALKVVENVLKVNPILGPQMFQPLLPSVFRGIIDGERYPMLMSTYLGVIGRVLLQNTSFFSLLLNQMACESGQELDQILGNMIEMWVDRMDNITQPERRKLSALALISLLPSLNSVIQDKFCGIIHVTLEGLYDVMTEDPETGTYKDCLLLSHFEEPKVTEDEEPPTEQDKRKKLLALKDPVHTVSLQQFVYEKLKAQQELLGEQGFHALMETVDTEVVAQLQEFLQGF", "length": 989, "header": "tr|A0A8V0YBZ9-1|A0A8V0YBZ9_CHICK Computationally mapped isoform of Importin-11 OS=Gallus gallus OX=9031 GN=IPO11 PE=1 SV=1 CANONICAL=A0A8V0YDA3-1" }, "locus": { "chromosome": "Z", "start_pos": 20114741, "end_pos": 20049175, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028673.1", "url": "https://www.ensembl.org/id/ENSGALT00010028673.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016482.1", "url": "https://www.ensembl.org/id/ENSGALP00010016482.1" } ] } }, { "isoform_ac": "A0A8V0YC04-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDA3/entry#A0A8V0YC04-1", "sequence": { "sequence": "MDLNSASSIVLQVLTQATSQDTAVLKPAEEQLKQWETQPGFYSVLLNIFTNHALDVNVRWLAVLYFKNGIDRYWRRVAPHALSEEEKTTLRAGLIANFNEPVNQIATQISVLIAKVARVDCPRQWPELIPTLLESVKVQDDLRQHRALLTFYHVTKTLASKRLAADRKLFYDLASGIYSFACSLWNHHTDTFLQQACTGNEAAASNSLERTLLSLKVLRKLTVHGFVEPHRSVEVMGFLHALFERLKQFLECSRNIRTGNVCRDRLEKTIILFTKVLLDFLDQHPFSFTPLIQRSLEFAVSYVFTEAGEGVVFERFIVQCMNLIKMIVKNYAYKPSKYIEDSSPETLEAHKIKTAFFTYPTLMEICRRLVTHYFLLTEEELTMWEEDPEGFTVEETGGDSWKYSLRPCTEVLFIDIFHEYNQTLTPVLLEMVHSLQGTTNLEDTSAILIKDAVYNAVGLAAYELFDSVDFDQWFKNQLLAELQVSHNRYKPIRRRVIWLIGQWISVKFKSDLRPMLYEAIRNLLQDQDLVVRIETATTLKLTVDDFEFRTDQFLPYLESMFTLLFQLLQEVTECDTKMHVLHVLSCVNERVNVQIRPYVGCLVQYLPLLWKQSEEHNMLRCAILTTLIHLVQGLGAESKNLYPFLLPIIQLSTDVSQPPHVYLLEDGLELWLVTLENSPCLTPELLRIFQNMSALLELSSENLKNCFKIINAYVFLSSTEFLQTYAVDLCRSFCELLKDITTEGQVQALKVVENVLKVNPILGPQMFQPLLPSVFRGIIDGERYPMLMSTYLGVIGRVLLQNTSFFSLLLNQMACESGQELDQILGNMIEMWVDRMDNITQPERRKLSALALISLLPSLNSCLLLSHFEEPKVTEDEEPPTEQDKRKKLLALKDPVHTVSLQQFVYEKLKAQQELLGEQGFHALMETVDTEVVAQLQEFLQGF", "length": 943, "header": "tr|A0A8V0YC04-1|A0A8V0YC04_CHICK Computationally mapped isoform of Importin-11 OS=Gallus gallus OX=9031 GN=IPO11 PE=1 SV=1 CANONICAL=A0A8V0YDA3-1" }, "locus": { "chromosome": "Z", "start_pos": 20114741, "end_pos": 20049175, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028680.1", "url": "https://www.ensembl.org/id/ENSGALT00010028680.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016488.1", "url": "https://www.ensembl.org/id/ENSGALP00010016488.1" } ] } }, { "isoform_ac": "A0A8V0YDA3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDA3/entry#A0A8V0YDA3-1", "sequence": { "sequence": "MTFIGKTTERCACVNELRLVVTSWFYLLAAEVLVAVCSVCCASHKIFMDLNSASSIVLQVLTQATSQDTAVLKPAEEQLKQWETQPGFYSVLLNIFTNHALDVNVRWLAVLYFKNGIDRYWRRVAPHALSEEEKTTLRAGLIANFNEPVNQIATQISVLIAKVARVDCPRQWPELIPTLLESVKVQDDLRQHRALLTFYHVTKTLASKRLAADRKLFYDLASGIYSFACSLWNHHTDTFLQQACTGNEAAASNSLERTLLSLKVLRKLTVHGFVEPHRSVEVMGFLHALFERLKQFLECSRNIRTGNVCRDRLEKTIILFTKVLLDFLDQHPFSFTPLIQRSLEFAVSYVFTEAGEGVVFERFIVQCMNLIKMIVKNYAYKPSKYIEDSSPETLEAHKIKTAFFTYPTLMEICRRLVTHYFLLTEEELTMWEEDPEGFTVEETGGDSWKYSLRPCTEVLFIDIFHEYNQTLTPVLLEMVHSLQGTTNLEDTSAILIKDAVYNAVGLAAYELFDSVDFDQWFKNQLLAELQVSHNRYKPIRRRVIWLIGQWISVKFKSDLRPMLYEAIRNLLQDQDLVVRIETATTLKLTVDDFEFRTDQFLPYLESMFTLLFQLLQEVTECDTKMHVLHVLSCVNERVNVQIRPYVGCLVQYLPLLWKQSEEHNMLRCAILTTLIHLVQGLGAESKNLYPFLLPIIQLSTDVSQPPHVYLLEDGLELWLVTLENSPCLTPELLRIFQNMSALLELSSENLKNCFKIINAYVFLSSTEFLQTYAVDLCRSFCELLKDITTEGQVQALKVVENVLKVNPILGPQMFQPLLPSVFRGIIDGERYPMLMSTYLGVIGRVLLQNTSFFSLLLNQMACESGQELDQILGNMIEMWVDRMDNITQPERRKLSALALISLLPSLNSVIQDKFCGIIHVTLEGLYDVMTEDPETGTYKDCLLLSHFEEPKVTEDEEPPTEQDKRKKLLALKDPVHTVSLQQFVYEKLKAQQELLGEQGFHALMETVDTEVVAQLQEFLQGF", "length": 1022, "header": "tr|A0A8V0YDA3-1|A0A8V0YDA3_CHICK Isoform 1 of Importin-11 OS=Gallus gallus OX=9031 GN=IPO11 PE=1 SV=1 CANONICAL=A0A8V0YDA3-1" }, "locus": { "chromosome": "Z", "start_pos": 20114741, "end_pos": 20043742, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028664.1", "url": "https://www.ensembl.org/id/ENSGALT00010028664.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016475.1", "url": "https://www.ensembl.org/id/ENSGALP00010016475.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:769679", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:769679", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A286Y8U4-1", "protein_name": "Importin-11", "gene_name": "ipo11", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDIQSASSVVLQALTQATSQDTAVLKPAEEQLRQWETQPGFYSVLLSIFNNHLLDVNVRWLAVLYFKNGIDRYWRRVAPHALSEEEKSSLRAGLITNFNEPVNQIATQIAVLIAKVARLDCPRQWPELIPILLESVKVQDSLQQHRALLTFYHVTKTLASKRLATDRRLFQDLASSIYSFACSLWNHHTDSFLQQIYSGDQQTALSSLERTLLSLKVLRKLTVHGFVDPQNNMEVMGFLNAVFERLKQFLECCRQVGPGSPCREKLEKTIILFTKVLLDFLEYHPCPFIPLIQRSLEFAVSYVFTEAGEGVVFERFIVQCMNLIKMIVKNDAYKPAKNIEDSKPESLEAHRIKTAFFTHQTLTEIGRRLVSKYFLLTEEELTMWEEDPESFAVEETGGDSWKYSLRPSTEVLFLDIFHNYSQTLTPVLLEMVQNLQGPSNVEDPVQMLMKDAVYNAVGLAAYELFDNVDFDQWFKNQLLGELQVSHNRYKLIRRRVIWLIGQWISVKFKPELRPLLYEVILSLMQDPDLVVRIETATTLKLAVDDFEFRTEQFLPYLESIFSLLFQLLQQVNECDTKMQVLHVISCVIERVSIQIRPYVGCLVQYLPLLWKQSEEHNMLRCAILTTLIHLVQGLGAESKNLYPFLLPVIQLSTDVSQPPHVYLLEDGLELWLVTLENSPAITPELLRIFQNMSPLLELSSENVRTCFQIINAYIYLSATDFLQNYAEALCRSFCELLSDITNEGQVQVLKVVEIAIKVSPILGSHMFQPLLPSVIRGIVEGERYPVVMSTYLGVTGRILLQNSGFFTSLLTQMAVEFNQEADQLLGSMIEMWVDRMDNITQPERRKLSALALLSLLPSDNSVIQDKFCGIINISVEALHDVMTEDPETATFKDCMLMSHFEEPKLTDDEEPPTEQDKRRKLLALEDPVHSVSLQQFVYEKLKAQQMLMGDQGFQALMETVDTEIVRQLQEFIQGM", "length": 975 }, "evidence": [ { "id": "A0A8V0YDA3", "url": "https://omabrowser.org/oma/group/A0A8V0YDA3/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A5G2QSF9-1", "protein_name": "Importin-11", "gene_name": "IPO11", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDLNSASTVVLQVLTQATSQDTAVLKPAEEQLKQWETQPGFYSVLLNIFTNHSLDINVRWLAVLYFKNGIDRYWRRVAPHALSEEEKSTLRAGLITNFNEPINQIATQIAVLIAKVARLDCPRQWPELIPTLIESVKVQDDLRQHRALLTFYHVTKTLASKCLAADRKLFYDLASGIYSFACSLWNHHTDTFLQQVSSGNEAAVLSSLERTLLSLKVLRKLTVNGFVEPHKNMEVMGFLHGIFERLKQFLECSRSIGTDNVCRERLEKTIILFTKVLLDFLDQHPFSFTPLIQRSLEFSVSYVFTEVGEGVTFERFIVQCMNLIKMIVKNYAYKPSKNFEDSSPETLEAHKIKMAFFTYPTLTEICRRLVSHYFLLTEEELTMWEEDPEGFTVEETGGDSWKYSLRPCTEVLFIDIFHEYNQTLTPVLLEMMQTLQGPTNVEDMNALLIKDAVYNAVGLAAFELFDSVDFDQWFKNQLLPELQVVHNRYKPLRRRVIWLIGQWISVKFKSDLRPMLYEAICNLLQDQDLVVRIETATTLKSTVDDFEFRTDQFLPYLETMFTLLFQLLQQVTECDTKMHVLHVLSCVIERVNVQIRPYVGCLVQYLPLLWKQSEEHNMLRCAILTTLIHLVQGLGADSKNLYPFLLPVIQLSTDVSQPPHVYLLEDGLELWLVTLENSPCITPELLRIFQNMSPLLELSSENLRTCFKIINGYIFLSSTEFLQTYAVGLCQSFCELLEEITSEGQVQVLKVVENALKVNPVLGPQMFQPILPCVFTGIIEGERYPVVMSTYLGVMGRVLLQNTSFFSSLLNEMARTFNQEMDQLLGNMIEMWVDRMDNITQPERRKLSALALLSLLPSDNSVIQDKFCGIINISVEGLHDVMTEDPETGTYKDCMLMSHLEEPKVTEDEEPPTEQDKRKKMLALKDPVHTVSLQQFIYEKLKAQQELLGEQGFQSLMETVDTEIVTQLQEFLQGF", "length": 975 }, "evidence": [ { "id": "A0A8V0YDA3", "url": "https://omabrowser.org/oma/group/A0A8V0YDA3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8C2QGD9-1", "protein_name": "Importin-11", "gene_name": "Ipo11", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MDLHSASSVVLQVLTQATSQDTAVLKPAEEQLKQWETQPGFYSVLLNIFTNHTLDINVRWLAVLYFKHGIDRYWRRVAPHALSEEEKSTLRAGLITNFNEPINQIATQIAVLIAKVARLDCPRQWPELIPTLVESVKVQDDLRQHRALLTFYHVTKTLASKRLAADRKLFYDLASGIYNFACSLWNHHTDTFLQQVSSGNESAVLSSLERTLLSLKVLRKLTVNGFVEPHKNMEVMGFLHGIFERLKQFLECSRSIGTDNACRDRLEKTIILFTKVLLDFLDQHPISFTPLIQRSLEFSVSYVFTEVGEGVTFERFIVQCMNLIKMIVKNYAYKPSKNFEDSSPETIEAHKIKMAFFTYPTLTEICRRLVSHYFLLTEEELTMWEEDPEGFTVEETGGDSWKYSLRPCTEVLFIDIFHEYNQTLTPVLLEMMQTLQGPTNVEDMNALLIKDAVYNAVGLAAFELFDSVDFDQWFKNQLLPELQVSHNRYKPLRRRVIWLIGQWISVKFKSDLRPMLYEAICNLLQDQDLVVRIETATTLKLTVDDFEFRTDQFLPYLETMFTLLFQLLQQVTECDTKMHVLHVLSCVIERVNVQIRPYVGCLVQYLPLLWKQSEEHNMLRCAILTTLIHLVQGLGADSKNLYPFLLPVIQLSTDVSQPPHVYLLEDGLELWLVTLENSPCVTPELLRIFQNMSPLLELSSENLRTCFKIINGYIFLSSTEFLQTYAVGLCQSFCELLPEITTEGQVQVLKVVESALKVNPVLGPQMFQPILPYVFRGVIEGERYPVVMSIYLAVMGRVLLQNTSFFSSLLNKMAHEFNQEMDQLLGNVIEMWVDRVDNITQPERKKLSALALLSLLPSDNSVIQDKFCGIINISVEALHDVMTEDPETRTYKDCMLMSHHEEPKVTEDEEPPTEQDKRKKMLALKDPVHTVSLQQFIYEKLKAQQEMLGEQGFQSLMETVDTEIVTQLQEFLQGF", "length": 975 }, "evidence": [ { "id": "A0A8V0YDA3", "url": "https://omabrowser.org/oma/group/A0A8V0YDA3/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8I6APG6-1", "protein_name": "Importin-11", "gene_name": "ENSRNOG00000062438", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDLNSASSVVLQVLTQATSQDTAVLKPAEEQLKQWETQPGFYSVLLNIFTNHTLDINVRWLAVLYFKHGIDRYWRRVAPHALSEEEKSTLRAGLITNFNEPINQIATQIAVLIAKVARLDCPRQWPELIPTLVESVKVQDDLRQHRALLTFYHVTKTLASKRLAADRKLFYDLASGIYNFACSLWNHHTDTFLQQVSSGNEAAVLSSLERTLLSLKVLRKLTVNGFVEPHKNMEVMGFLHGIFERLKQFLECSRSIGTDNVCRDRLEKTIILFTKVLLDFLDQHPISFTPLIQRSLEFSVSYVFTEVGEGVTFERFIVQCMNLIKMIVKNYAYKPSKNFEDSSPETLEAHKIKMAFFTYPTLTEICRRLVSHYFLLTEEELTMWEEDPEGFTVEETGGDSWKYSLRPCTEVLFIDIFHEYNQTLTPVLLEMMQTLQGPTNVEDMNALLIKDAVYNAVGLAAFELFDSVDFDQWFKTQLLPELQVSHNRYKPLRRRVIWLIGQWISVKFKSDLRPRLYEAICNLLQDQDLVVRIETATTLKLTVDDFEFRTDQFLPYLETMFTLLFQLLQQVTECDTKMHVLHVLSCVIERVNIQIRPYVGCLVQYLPLLWKQSEEHNMLRCAILTTLIHLVQGLGADSKNLYPFLLPVIQLSTDVSQPPHVYLLEDGLELWLVTLENSPCVTPELLRIFQNMSPLLELSSENLRTCFKIINGYIFLSSTEFLQTYAAGLCQSFYELLPEITTEGQVQVLKVVENTLKVNPVLGPQMFQRILPYVFRGVIEGERYPVVMSIYLAVMGRVLLQNASFFSSLLNEMGHEFNQEMDQLLGNVIEMWVDRMDNITQPERKKLSALALLSLLPSDNSVIQDKFCGIINISVEALHDVMTEDPETRTYKDCMLMSHHEEPKVTEDEEPPTEQDKRKKMLALKDPVHTVSLQQFIYEKLKAQQEILGEQGFQSLMETVDTEIVTQLQEFLQGF", "length": 975 }, "evidence": [ { "id": "A0A8V0YDA3", "url": "https://omabrowser.org/oma/group/A0A8V0YDA3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F4IYK6-1", "protein_name": "ARM repeat superfamily protein", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MALSASDLPAMYTLLANSMSGDETVRRPAEAALSLSESRPGFCSCLMEVIASKDLVSHVDVRLMASVYFKNSINRHWKSRRNSWSMSNEEKSHLRQKLLSHLREENYQIAEMLAVLISKIARFDYPREWPDLFSVLAQQLHSADVLASHRIFLILFRTLKELSTKRLTADQKTFAEISSQFFDFSWHLWQTDVQTILHGFSTMVQSYGSNSAEQHHDELFLTCERWFLCLKIVRQLIISGFLSDANNIQEIQPVKEVSPALLNAAQSFLPYYSSFQNRDPKFWEFVKKACVKLMKVLGAIQSRHPFSFGDKCALPVVVDFCLNKITDPEQALLPFEDFFIQCMVMVKSVLECKEYKPSRTGRVMDDNGDTFEQRKKNASNTVGGIVSSLLPNERIVLLCNVLVRRYFVLTASDLEEWYQNPESFHHEQDMIQWTEKLRPCAEALYMVLFENYSQLLGPIVVSILQEAMNNCPPSVTEITPALLLKDAAYAATAYVYYELSNYLNFRDWFNGALSLELSNDHPNRRIIHRKVAMILGHWVSEIKDDTKRAVYCALIKLLQDNDLAVKLAASRSLCLHVEDANFSEQSFLDLLPICWDSCFKMVEVVQEFDSKVQILNLISTLIGHVSEVIPYAQKLVQFFQKVWEESSGESLLQIQLLVALRNFVIALGYQSPICYSILLPILQKGIDINSPDSLNLLEDSMALWETTLSYAPMMVPQLLALFPYMVEIIERSFDHLQVAVSIMDSYIILDGGEFLNMHASSVAKILDLIVGNVNDKGLLSILPVIDILVQCFPVEVPPLISSCLQKLVIICLSGGDDRDPSKTAVKVSSAAILARILVMNTTYLAQLTSDSSLSVLLQQAGVPVEDNILLCLIDIWLDKVDHASPMQQKTFGLALSIILTLRMPQVLDKLDLILSTCTSVILGENKDLTEEESSGDMSSSRSQGEETPPSKELRKSQIKVSDPIYQMSLENSTRENLQTCSTLHGDAFNSAISRMHPSALAQVKQALKLP", "length": 1010 }, "evidence": [ { "id": "A0A8V0YDA3", "url": "https://omabrowser.org/oma/group/A0A8V0YDA3/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q02932-1", "protein_name": "Importin beta-like protein KAP120", "gene_name": "KAP120", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MASSLNELNLVQVLEQASNPQHIRSDVQKLAEQQLRQWETQAGFHYLLQSIYLNLSNSLQIRWLAVIQFKNGVDKYWRSTRINAIPKDEKASIRGRLFEMIDEQNNQLCIQNAQASARIARLDFPVEWPTLFEDLENLLNDEIIRKDSVKIYNILMHINQIVKVLGTARIGRCRPAMQSKVPLILPLIVRIYLQSFEEWTTSSNLNYEDLSSLQVSYLALKVLRRIICEGYDRPQTDQSVCDFIKLSVSHFEMLISNHENFKKFDIYEKFIKCLGKLYFNLVTGSPANFILLPCSTQILITYTRLIFDKAPKVYRENSDVTGDFWEQTAIRGLLILKRVINFIHKKGAITLKARSDKLTIDASINKINTEFLNENLITRLVDTLMEWYLRLRPTELENWFMDPEEWINEQMATSYEYQIRPCAENVFQDLMNTFSELLVPYLLKKIENDASKLSNSLDDFLRKDAIYASFQLSASAVSEMVDFDRLLIQVFLPEATNTNISGDELRIIRRRVALIINEWSTVKCSEESKSLCYKLFTNFLTDEDDKVVLLTTVQTVRTMVDDWNFNKDTFQPFLTENVHLLLRKILPSVSLTETRLYVLNTLSDIIIQTKPLISRDLLVEILQIIPNLWEIATNNASEAILANALLRLLRNLVSSLGSQSHLTWDIAIPVVALACDPSSMQYQLLSEDGYELWGMLLQNFSSHDQEFDDKFVELVPFLKYGIETHTEILPTLLEIIKSYALILNPVDFFSNNTFQDIFKQMSKYLLKLREDSFQLVLEIWEILILSNESDYENLLLQKFYETGVLSALFDAIFLEEAPSSYLCSQIIQIIARISYVNPDALMTFLATYHDNLPTSNENARMPESIRKIVSKDQTYDSVVNKLLTGWIVCFRDIFDPKFKKVHILGISSLLRTGLVPILTEFSSIASLWIEMLEEINETNRGDCEKYHLNDIVTEQSIAFHPLTAEQLRYHQLCKNNDPVHNISLKDFISQSMEYLESHLGVERYQEFLKTINPSLLENLQMFLSIQPQEARP", "length": 1032 }, "evidence": [ { "id": "A0A8V0YDA3", "url": "https://omabrowser.org/oma/group/A0A8V0YDA3/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q54WF0-1", "protein_name": "Importin N-terminal domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNKEIVAQLLQATLSSDHTRVQAESQVQLLTREKGFSSILLEIFGDQSIDKSIRNLSIVLFKNIITNNWRRKDNTLFSEEEKQDYRNRVLLLLNNPNETCKNGVDILAGVIGTMARVDFPSNWPNLLTNLLELFEKSSSEQIKIVSLKTIKFVVKELASRRFVIDRTFFSQFSNTIFNYFIQIWRSGVKRLIELMIEGGNLAQHESFFILVYYVSKILRRVVEYGYTDYQNSPEICQYFSDIFTGLPEILKLRTRVTNPKILELVDKFIYINQKTIIKSQLQNPLTFINLLLPSLRFFAGQCLYYNPHDELKIEWNTTEDYQSVMTQSLNFLKQVIDCSSYQGDYLDSETDEKQSISNLAIKSGGKINGNGSIQIAQQTIKQFFNKELLSELLKALVSHYLIINREEVERWEDSPEEYIQELQVNDSVYELKPSAYNLFILLMRHFHQDSVSIVVSMLEFVTSPSFNTELTSEKICLKEACYMTIGLGYHDLMDIVNFSQVFISIFVPELHSADERFKIIKRRILWLVSYWVGKIPDQYKESVVKLLLEFLKNSDIVIALTALDALKAYIDDFNFDHHSYQPYLKETLESVIGLFSRSTNETTKSNLLSALASIFVKFNESIKPFSTVILQLFQHLWNGGKEQPIVKSAVLRSFAFFLQALNSDPADFYSLLFPIIEFSISQEDEKVYLLEDGLELWYRTMVLVPTLSQPQQPLIQMFKHWFTIIAQSLENSEICFKILDTYLLLGQIDFLKIYGAELSSTLYDIIGDLGEEYTELIVSAIMRIIQVVPNPQDSITLLIEQCLFKILSLIISRKETSTLVLIEYFSIFSRIMTMNPLSFFQLFDRYPLELLDKDGEYYDPSNFNNDNNDDDDDDDDGQSKIKEMPQNKSQLLQQFFEIYFDKIDSTSSSDQRKLIAIGLSNLLAIPREEVYPQIGEIITNVVGIRADISDITHDDIYCNDGDEVSGVQIQSDHIFQVDPLTTIDLSTYLYQKIQECSNLFGTENFQKAIVNVHPSILSLAIPPKN", "length": 1025 }, "evidence": [ { "id": "A0A8V0YDA3", "url": "https://omabrowser.org/oma/group/A0A8V0YDA3/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q8K2V6-1", "protein_name": "Importin-11", "gene_name": "Ipo11", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDLNSASSVVLQVLTQATSQDTAVLKPAEEQLKQWETQPGFYSVLLNIFTNHTLDINVRWLAVLYFKHGIDRYWRRVAPHALSEEEKSTLRAGLITNFNEPINQIATQIAVLIAKVARLDCPRQWPELIPTLVESVKVQDDLRQHRALLTFYHVTKTLASKRLAADRKLFYDLASGIYNFACSLWNHHTDTFLQHVSSGNEAAVLSSLERTLLSLKVLRKLTVNGFVEPHKNMEVMGFLHGIFERLKQFLECSRSIGTDNVCRDRLEKTIILFTKVLLDFLDQHPISFTPLIQRSLEFSVSYVFTEVGEGVTFERFIVQCMNLIKMIVKNYAYKPSKNFEDSSPETLEAHKIKMAFFTYPTLTEICRRLVSHYFLLTEEELTMWEEDPEGFTVEETGGDSWKYSLRPCTEVLFIDIFHEYNQTLTPVLLEMMQTLEGPTNVEDMNALLIKDAVYNAVGLAAFELFDSVDFDQWFKTQLLPELQVSHNRYKPLRRRVIWLIGQWISVKFKSDLRPMLYEAICNLLQDQDLVVRIETATTLKLTVDDFEFRTDQFLPYLETMFTLLFQLLQQVTECDTKMHVLHVLSCVIERVNVQIRPYVGCLVQYLPLLWKQSEEHNMLRCAILTTLIHLVQGLGADSKNLYPFLLPVIQLSTDVSQPPHVYLLEDGLELWLVTLENSPCVTPELLRIFQNMSPLLELSSENLRTCFKIINGYIFLSSTEFLQTYAAGLCQSFYELLPEITTEGQVQVLKVVENALKVNPVLGPQMFQRILPCVFRGVIEGERYPVVMSIYLAVMGRVLLQNTSFFSSLLNEMGHEFNQEMDQLLGNVIEMWVDRMDNITQPERKKLSALALLSLLPSDNSVIQDKFCGIINISVEALHDVMTEDPETRTYKDCMLMSQHEEPKVTEDEEPPTEQDKRKKMLALKDPVHTVSLQQFIYEKLKAQQEILGEQGFQSLMETVDTEIVTQLQEFLQGF", "length": 975 }, "evidence": [ { "id": "A0A8V0YDA3", "url": "https://omabrowser.org/oma/group/A0A8V0YDA3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9UI26-1", "protein_name": "Importin-11", "gene_name": "IPO11", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDLNSASTVVLQVLTQATSQDTAVLKPAEEQLKQWETQPGFYSVLLNIFTNHTLDINVRWLAVLYFKHGIDRYWRRVAPHALSEEEKTTLRAGLITNFNEPINQIATQIAVLIAKVARLDCPRQWPELIPTLIESVKVQDDLRQHRALLTFYHVTKTLASKRLAADRKLFYDLASGIYNFACSLWNHHTDTFLQEVSSGNEAAILSSLERTLLSLKVLRKLTVNGFVEPHKNMEVMGFLHGIFERLKQFLECSRSIGTDNVCRDRLEKTIILFTKVLLDFLDQHPFSFTPLIQRSLEFSVSYVFTEVGEGVTFERFIVQCMNLIKMIVKNYAYKPSKNFEDSSPETLEAHKIKMAFFTYPTLTEICRRLVSHYFLLTEEELTMWEEDPEGFTVEETGGDSWKYSLRPCTEVLFIDIFHEYNQTLTPVLLEMMQTLQGPTNVEDMNALLIKDAVYNAVGLAAYELFDSVDFDQWFKNQLLPELQVIHNRYKPLRRRVIWLIGQWISVKFKSDLRPMLYEAICNLLQDQDLVVRIETATTLKLTVDDFEFRTDQFLPYLETMFTLLFQLLQQVTECDTKMHVLHVLSCVIERVNMQIRPYVGCLVQYLPLLWKQSEEHNMLRCAILTTLIHLVQGLGADSKNLYPFLLPVIQLSTDVSQPPHVYLLEDGLELWLVTLENSPCITPELLRIFQNMSPLLELSSENLRTCFKIINGYIFLSSTEFLQTYAVGLCQSFCELLKEITTEGQVQVLKVVENALKVNPILGPQMFQPILPYVFKGIIEGERYPVVMSTYLGVMGRVLLQNTSFFSSLLNEMAHKFNQEMDQLLGNMIEMWVDRMDNITQPERRKLSALALLSLLPSDNSVIQDKFCGIINISVEGLHDVMTEDPETGTYKDCMLMSHLEEPKVTEDEEPPTEQDKRKKMLALKDPVHTVSLQQFIYEKLKAQQEMLGEQGFQSLMETVDTEIVTQLQEFLQGF", "length": 975 }, "evidence": [ { "id": "A0A8V0YDA3", "url": "https://omabrowser.org/oma/group/A0A8V0YDA3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "nuclear envelope", "id": "GO:0005635", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005635", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YDA3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDA3" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YDA3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDA3" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YDA3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDA3" } ], "pmid": "" }, { "name": "nucleus", "id": 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"" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "protein import into nucleus", "id": "GO:0006606", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006606", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YDA3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDA3" } ], "pmid": "" }, { "name": "intracellular protein transport", "id": "GO:0006886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YDA3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDA3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 468, "end_pos": 470, "annotation": "n_glycosylation_sequon" }, { "start_pos": 738, "end_pos": 740, "annotation": "n_glycosylation_sequon" }, { "start_pos": 849, "end_pos": 851, "annotation": "n_glycosylation_sequon" }, { "start_pos": 885, "end_pos": 887, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YDA4-1", "uniprot_ac": "A0A8V0YDA4", "uniprot_id": "A0A8V0YDA4_CHICK", "mass": { "chemical_mass": 45633.0, "monoisotopic_mass": 45633.0 }, "refseq": {}, "gene_names": [ { "name": "MTERF3", "type": "recommended", "evidence": [ { "id": "A0A8V0YDA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDA4" } ] } ], "protein_names": [ { "name": "Transcription termination factor 3, mitochondrial", "type": "recommended", "evidence": [ { "id": "A0A8V0YDA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDA4/entry#names_and_taxonomy" } ] }, { "name": "mTERF domain-containing protein 1, mitochondrial", "type": "synonym", "evidence": [ { "id": "A0A8V0YDA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDA4/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YDA4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDA4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MTERF3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDA4", "locus": { "chromosome": "2", "start_pos": 126411070, "end_pos": 126428695, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010011445", "url": "https://www.ensembl.org/id/ENSGALG00010011445" } ] } } ], "crossref": [ { "id": "A0A8V0YDA4", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YDA4", "database": "AlphaFoldDB", "categories": [] }, { "id": "420237", "url": "https://www.ncbi.nlm.nih.gov/gene/420237", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003690", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003690", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038538", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038538", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:420237", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420237", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "NPFWLMF", "url": "https://omabrowser.org/oma/group/NPFWLMF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y4U0", "url": "https://www.orthodb.org/?gene=A0A8V0Y4U0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y9J5", "url": "https://www.orthodb.org/?gene=A0A8V0Y9J5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YDA4", "url": "https://www.orthodb.org/?gene=A0A8V0YDA4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13068", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13068", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13068:SF194", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13068:SF194", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02536", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02536", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-5205685", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5205685", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001006348", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006348", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Y4U0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y4U0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y4U0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y4U0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y9J5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9J5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y9J5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9J5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YDA4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDA4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YDA4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDA4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAVWARQVARCGWLRAAGLLGLRSRSGAARACCGAAPLPALLSGHRLPPWRLRVSVDCAQPSRAKGEACAPRSSLPVAVKQEQAAPETVSDLSAAKLYEDWDDVPPSSALEEISEEEAVKIIADPLLPPQSSTLRDYVDHSETLTKLVHLGVDLSQVEKRQKAGQLLLTLDFEKDITKILLFLKDVGIEDNQLGPFLTKNPYILGEELEALETRVAYLKSKKFGNAEITQMVSRAPYLLLFSVERLDNRLGFFKNELGLSVKKTKDLVIRFPRLLTGKLEPVKENLQVCQVEFGFERNEVQQIAFKTPKILTASKKRLRQTFDYLHNIMGIPHNMLTRFPQVFNSKLLRIKERHMFLIFLGRAQYDPTKPSYISLDQLVSLPDEVFCTEIAKASMQDFEKFLKTI", "length": 405, "header": "tr|A0A8V0YDA4-1|A0A8V0YDA4_CHICK Isoform 1 of Transcription termination factor 3, mitochondrial OS=Gallus gallus OX=9031 GN=MTERF3 PE=3 SV=1 CANONICAL=A0A8V0YDA4-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Y4U0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDA4/entry#A0A8V0Y4U0-1", "sequence": { "sequence": "MAVWARQVARCGWLRAAGLLGLRSRSGAARACCGAAPLPALLSGHRLPPWRLRVSVDCAQPSRAKGEACAPRSSLPVAVKQEQAAPETVSDLSAAKLYEDWDDVPPSSALEEISEEEAVKIIADPLLPPQSSTLRDYVDHSETLTKLVHLGVDLSQVEKRQKAGQLLLTLDFEKDITKILLFLKDVGIEDNQLGPFLTKNPYILGEELEALETRVAYLKSKKFGNAEITQMVSRAPYLLLFSVERLDNRLGFFKNELGLSVKKTKDLVIRFPRLLTGKLEPVKENLQVCQVEFGFERNEVQQIAFKTPKILTASKKRLRQTFDYLHNIMGIPHNMLTRFPQVSTPLLFKNQLHPTTVSEEKAYSNVCGDLKVYLKRVRWVYVDCY", "length": 385, "header": "tr|A0A8V0Y4U0-1|A0A8V0Y4U0_CHICK Computationally mapped isoform of Mitochondrial transcription termination factor 3 OS=Gallus gallus OX=9031 GN=MTERF3 PE=3 SV=1 CANONICAL=A0A8V0YDA4-1" }, "locus": { "chromosome": "2", "start_pos": 126428540, "end_pos": 126411805, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027389.1", "url": "https://www.ensembl.org/id/ENSGALT00010027389.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015643.1", "url": "https://www.ensembl.org/id/ENSGALP00010015643.1" } ] } }, { "isoform_ac": "A0A8V0Y9J5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDA4/entry#A0A8V0Y9J5-1", "sequence": { "sequence": "MAVWARQVARCGWLRAAGLLGLRSRSGAARACCGAAPLPALLSGHRLPPWRLRVSVDCAQPSRAKGEACAPRSSLPVAVKQEQAAPETVSDLSAAKLYEDWDDVPPSSALEEISEEEAVKIIADPLLPPQSSTLRDYVDHSETLTKLVHLGVDLSQVEKRQKDVGIEDNQLGPFLTKNPYILGEELEALETRVAYLKSKKFGNAEITQMVSRAPYLLLFSVERLDNRLGFFKNELGLSVKKTKDLVIRFPRLLTGKLEPVKENLQVCQVEFGFERNEVQQIAFKTPKILTASKKRLRQTFDYLHNIMGIPHNMLTRFPQVFNSKLLRIKERHMFLIFLGRAQYDPTKPSYISLDQLVSLPDEVFCTEIAKASMQDFEKFLKTI", "length": 383, "header": "tr|A0A8V0Y9J5-1|A0A8V0Y9J5_CHICK Computationally mapped isoform of Transcription termination factor 3, mitochondrial OS=Gallus gallus OX=9031 GN=MTERF3 PE=3 SV=1 CANONICAL=A0A8V0YDA4-1" }, "locus": { "chromosome": "2", "start_pos": 126428540, "end_pos": 126412012, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027388.1", "url": "https://www.ensembl.org/id/ENSGALT00010027388.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015642.1", "url": "https://www.ensembl.org/id/ENSGALP00010015642.1" } ] } }, { "isoform_ac": "A0A8V0YDA4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDA4/entry#A0A8V0YDA4-1", "sequence": { "sequence": "MAVWARQVARCGWLRAAGLLGLRSRSGAARACCGAAPLPALLSGHRLPPWRLRVSVDCAQPSRAKGEACAPRSSLPVAVKQEQAAPETVSDLSAAKLYEDWDDVPPSSALEEISEEEAVKIIADPLLPPQSSTLRDYVDHSETLTKLVHLGVDLSQVEKRQKAGQLLLTLDFEKDITKILLFLKDVGIEDNQLGPFLTKNPYILGEELEALETRVAYLKSKKFGNAEITQMVSRAPYLLLFSVERLDNRLGFFKNELGLSVKKTKDLVIRFPRLLTGKLEPVKENLQVCQVEFGFERNEVQQIAFKTPKILTASKKRLRQTFDYLHNIMGIPHNMLTRFPQVFNSKLLRIKERHMFLIFLGRAQYDPTKPSYISLDQLVSLPDEVFCTEIAKASMQDFEKFLKTI", "length": 405, "header": "tr|A0A8V0YDA4-1|A0A8V0YDA4_CHICK Isoform 1 of Transcription termination factor 3, mitochondrial OS=Gallus gallus OX=9031 GN=MTERF3 PE=3 SV=1 CANONICAL=A0A8V0YDA4-1" }, "locus": { "chromosome": "2", "start_pos": 126428540, "end_pos": 126412012, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027387.1", "url": 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"MFCSALRNILRNSQNAAKNATITSQIRNLRGQQSVHHEVEVLTSPGITTKQNDKKTEPAECEGSKEVALDFRNREAHVPSFNLAAYVNNSSTLQQFLSLGVDLHSIERRKGLGDFVLKLDFEKNVKPYITFLVDQGVSPDDFGRMFTKNPLLFKEDLDDLQTRVNYLKSKRFSDEARQRILTQNPYWLMFSTRRVDRRLGYFQKEFKLSGHDLRLLATREPNAITYNMEHLRKSVFTLKEEMGFNAKELSDLVVRKPRLLMIPPDDLVERFSYIHQDMGLPHAQIVQCPELLASREFRLRERHEFLKLLGRAQYDPQKDLYISPKTIVEGNNFYFVRNVAKSDLETFDLFLKTR", "length": 354 }, "evidence": [ { "id": "A0A8V0YDA4", "url": "https://omabrowser.org/oma/group/A0A8V0YDA4/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YDA4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDA4" } ], "pmid": "" }, { "name": "mitochondrial matrix", "id": "GO:0005759", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005759", "evidence": 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computational analysis. This record is derived from a genomic sequence (NC_052538.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040560000", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040560000" } ] }, { "annotation": "Inhibits factor X (X(a)) directly and, in a Xa-dependent way, inhibits VIIa/tissue factor activity, presumably by forming a quaternary Xa/LACI/VIIa/TF complex. It possesses an antithrombotic action and also the ability to associate with lipoproteins in plasma.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YDC8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDC8#function" }, { "database": "UniProtKB", "id": "ARBA00057773", "url": "https://www.uniprot.org/uniprotkb/ARBA00057773#function" }, { "database": "UniProtKB", "id": "A0A8V0YJP8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJP8#function" }, { "database": "UniProtKB", "id": "A0A8V0YJQ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJQ3#function" }, { "database": "UniProtKB", "id": "A0A8V0YJQ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJQ8#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YDC8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDC8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TFPI", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDC8", "locus": { "chromosome": "7", "start_pos": 1170078, "end_pos": 1127092, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013303", "url": "https://www.ensembl.org/id/ENSGALG00010013303" } ] } } ], "crossref": [ { "id": "A0A8V0YDC8", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YDC8", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd22613", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22613", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd22614", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22614", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd22615", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22615", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "423989", "url": "https://www.ncbi.nlm.nih.gov/gene/423989", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002223", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002223", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008296", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008296", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020901", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020901", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036880", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036880", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050098", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050098", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "WWILCAV", "url": "https://omabrowser.org/oma/group/WWILCAV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YDC8", "url": "https://www.orthodb.org/?gene=A0A8V0YDC8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YJP8", "url": "https://www.orthodb.org/?gene=A0A8V0YJP8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YJQ3", "url": "https://www.orthodb.org/?gene=A0A8V0YJQ3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YJQ8", "url": "https://www.orthodb.org/?gene=A0A8V0YJQ8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10083", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10083", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10083:SF328", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10083:SF328", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10083:SF376", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10083:SF376", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00014", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00014", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-9769735", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9769735", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9769739", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9769739", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_040560000", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040560000", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YDC8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDC8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YDC8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDC8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJP8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJP8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJP8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJP8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJQ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJQ3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJQ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJQ3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJQ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJQ8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJQ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJQ8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRKMKGRKRGCFLPLTFVLLFVCITGHATDDSDGEEEDVLGVPLPPLKLGHSDCALKADEGPCKAIHVRFYFNIQSRECEIFEYGGCHGNANNFLTLEECQNKCVVTELPLEVMLAKNEREKPNFCYQEKDPGICRGFFSRYFYNKETKICEIFKYGGCLGNQNNFKSLEECQTTCQGNPNLLSVAPDEEHPNHMNSSSPEEERNQFPGIVEPPPIPSLCMTPMDRGLCRAKETRFFYNYSTGRCRPFTYSGCGGNENNFTSRKSCLRICRKGMGTDIATDYHKRQVSCMLWAEIFLQFLVVSIGLIECNS", "length": 311, "header": "tr|A0A8V0YDC8-1|A0A8V0YDC8_CHICK Isoform 1 of Tissue factor pathway inhibitor OS=Gallus gallus OX=9031 GN=TFPI PE=4 SV=1 CANONICAL=A0A8V0YDC8-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YDC8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDC8/entry#A0A8V0YDC8-1", "sequence": { "sequence": "MRKMKGRKRGCFLPLTFVLLFVCITGHATDDSDGEEEDVLGVPLPPLKLGHSDCALKADEGPCKAIHVRFYFNIQSRECEIFEYGGCHGNANNFLTLEECQNKCVVTELPLEVMLAKNEREKPNFCYQEKDPGICRGFFSRYFYNKETKICEIFKYGGCLGNQNNFKSLEECQTTCQGNPNLLSVAPDEEHPNHMNSSSPEEERNQFPGIVEPPPIPSLCMTPMDRGLCRAKETRFFYNYSTGRCRPFTYSGCGGNENNFTSRKSCLRICRKGMGTDIATDYHKRQVSCMLWAEIFLQFLVVSIGLIECNS", "length": 311, "header": "tr|A0A8V0YDC8-1|A0A8V0YDC8_CHICK Isoform 1 of Tissue factor pathway inhibitor OS=Gallus gallus OX=9031 GN=TFPI PE=4 SV=1 CANONICAL=A0A8V0YDC8-1" }, "locus": { "chromosome": "7", "start_pos": 1168971, "end_pos": 1139987, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032004.1", "url": "https://www.ensembl.org/id/ENSGALT00010032004.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018794.1", "url": "https://www.ensembl.org/id/ENSGALP00010018794.1" } ] } }, { "isoform_ac": "A0A8V0YJP8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDC8/entry#A0A8V0YJP8-1", "sequence": { "sequence": "MKGRKRGCFLPLTFVLLFVCITGHATDDSDGEEEDVLGVPLPPLKLGHSDCALKADEGPCKAIHVRFYFNIQSRECEIFEYGGCHGNANNFLTLEECQNKCVVTELPLEVMLAKNEREKPNFCYQEKDPGICRGFFSRYFYNKETKICEIFKYGGCLGNQNNFKSLEECQTTCQGNPNLLSVAPDEEHPNHMNSSSPEEERNQFPGIVVNLLPTAPNEEESHTVNSSYLEEEYKQFPSSFG", "length": 241, "header": "tr|A0A8V0YJP8-1|A0A8V0YJP8_CHICK Computationally mapped isoform of Tissue factor pathway inhibitor OS=Gallus gallus OX=9031 GN=TFPI PE=4 SV=1 CANONICAL=A0A8V0YDC8-1" }, "locus": { "chromosome": "7", "start_pos": 1163854, "end_pos": 1152836, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031996.1", "url": "https://www.ensembl.org/id/ENSGALT00010031996.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018786.1", "url": "https://www.ensembl.org/id/ENSGALP00010018786.1" } ] } }, { "isoform_ac": "A0A8V0YJQ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDC8/entry#A0A8V0YJQ3-1", "sequence": { "sequence": "MRKMKGRKRGCFLPLTFVLLFVCITGHATDDSDGEEEDVLGVPLPPLKLGHSDCALKADEGPCKAIHVRFYFNIQSRECEIFEYGGCHGNANNFLTLEECQNKCVVTELPLEVMLAKNEREKPNFCYQEKDPGICRGFFSRYFYNKETKICEIFKYGGCLGNQNNFKSLEECQTTCQGNPNLLSVAPDEEHPNHMNSSSPEEERNQFPGIVEPPPIPSLCMTPMDRGLCRAKETRFFYNYSTGRCRPFTYSGCGGNENNFTSRKSCLRICRKGFIKKKDGRRLIRIKKKKKQLLKTKTVGEETIHGRIQF", "length": 310, "header": "tr|A0A8V0YJQ3-1|A0A8V0YJQ3_CHICK Computationally mapped isoform of Tissue factor pathway inhibitor OS=Gallus gallus OX=9031 GN=TFPI PE=4 SV=1 CANONICAL=A0A8V0YDC8-1" }, "locus": { "chromosome": "7", "start_pos": 1169325, "end_pos": 1139987, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032001.1", "url": "https://www.ensembl.org/id/ENSGALT00010032001.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018791.1", "url": "https://www.ensembl.org/id/ENSGALP00010018791.1" } ] } }, { "isoform_ac": "A0A8V0YJQ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDC8/entry#A0A8V0YJQ8-1", "sequence": { "sequence": "MKGRKRGCFLPLTFVLLFVCITGHATDDSDGEEEDVLGVPLPPLKLGHSDCALKADEGPCKAIHVRFYFNIQSRECEIFEYGGCHGNANNFLTLEECQNKCVVTELPLEVMLAKNEREKPNFCYQEKDPGICRGFFSRYFYNKETKICEIFKYGGCLGNQNNFKSLEECQTTCQGNPNLLSVAPDEEHPNHMNSSSPEEERNQFPGIVGRNSASHLTSYALRCRKPFCQTVPLLPSFA", "length": 238, "header": "tr|A0A8V0YJQ8-1|A0A8V0YJQ8_CHICK Computationally mapped isoform of Tissue factor pathway inhibitor OS=Gallus gallus OX=9031 GN=TFPI PE=4 SV=1 CANONICAL=A0A8V0YDC8-1" }, "locus": { "chromosome": "7", "start_pos": 1168098, "end_pos": 1152836, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032006.1", "url": "https://www.ensembl.org/id/ENSGALT00010032006.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018796.1", "url": "https://www.ensembl.org/id/ENSGALP00010018796.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-9769735", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9769735", "resource": "Reactome", "description": "Initiation of coagulation cascade" }, { "id": "R-GGA-9769739", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9769739", "resource": "Reactome", "description": "Regulation of clotting cascade" } ], "orthologs": [ { "uniprot_canonical_ac": "B0S6C1-1", "protein_name": "Tissue factor pathway inhibitor", "gene_name": "tfpia", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAPYLNSSCKPLLLLSLFGVCFARFERSDGVRSELRIFHQSCALKKDEGPCKAMKDRFYFDIDTGRCEPFEYGGCQGNANNFETLQDCEEMCLVTENKSPCHLEDEPGPCRGLVPRYFFDQKSQECKQFFYGGCFGNANNFKTIKACQQRCQLTAVLKSEEEEAKPVIESPAIHDDAHLNSSHSALRRVSQPAKQEAEFSPPELCMSAVDRGDCDGSERRYVFNPRIGRCQVFRYSGCGGNKNNFIHKRHCMKMCMKDQHRRKQIRIKTRNSNILFRSV", "length": 279 }, "evidence": [ { "id": "A0A8V0YDC8", "url": "https://omabrowser.org/oma/group/A0A8V0YDC8/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "O54819-1", "protein_name": "Tissue factor pathway inhibitor", "gene_name": "Tfpi", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTYKMKKEYAFWATVCLLLSLVPEFLNALSEEADDTDSELGSMKPLHTFCAMKADDGPCKAMIRSYFFNMYTHQCEEFIYGGCEGNENRFDTLEECKKTCIPGYEKTAVKAASGAERPDFCFLEEDPGLCRGYMKRYLYNNQTKQCERFVYGGCLGNRNNFETLDECKKICENPVHSPSPVNEVQMSDYVTDGNTVTDRSTVNNIVVPQSPKVPRRRDYRGRPWCLQPADSGLCKASERRFYYNSATGKCHRFNYTGCGGNNNNFTTRRRCLRSCKTGLIKNKSKGVVKIQRRKAPFVKVVYESIN", "length": 306 }, "evidence": [ { "id": "A0A8V0YDC8", "url": "https://omabrowser.org/oma/group/A0A8V0YDC8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P10646-1", "protein_name": "Tissue factor pathway inhibitor", "gene_name": "TFPI", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MIYTMKKVHALWASVCLLLNLAPAPLNADSEEDEEHTIITDTELPPLKLMHSFCAFKADDGPCKAIMKRFFFNIFTRQCEEFIYGGCEGNQNRFESLEECKKMCTRDNANRIIKTTLQQEKPDFCFLEEDPGICRGYITRYFYNNQTKQCERFKYGGCLGNMNNFETLEECKNICEDGPNGFQVDNYGTQLNAVNNSLTPQSTKVPSLFEFHGPSWCLTPADRGLCRANENRFYYNSVIGKCRPFKYSGCGGNENNFTSKQECLRACKKGFIQRISKGGLIKTKRKRKKQRVKIAYEEIFVKNM", "length": 304 }, "evidence": [ { "id": "A0A8V0YDC8", "url": "https://omabrowser.org/oma/group/A0A8V0YDC8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q02445-1", "protein_name": "Tissue factor pathway inhibitor", "gene_name": "Tfpi", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTNKLKKDHAFWAAVCLLLSIVPELLNALPEEDDDTINTDSELRPMKPLHTFCAMKAEDGPCKAMIRSYYFNMNSHQCEEFIYGGCRGNKNRFDTLEECRKTCIPGYKKTTIKTTSGAEKPDFCFLEEDPGICRGFMTRYFYNNQSKQCEQFKYGGCLGNSNNFETLEECRNTCEDPVNEVQKGDYVTNQITVTDRTTVNNVVIPQATKAPSQWDYDGPSWCLEPADSGLCKASEKRFYYNPAIGKCRQFNYTGCGGNNNNFTTKQDCNRACKKDSSKKSSKRAKTQRRRKSFVKVMYENIH", "length": 302 }, "evidence": [ { "id": "A0A8V0YDC8", "url": "https://omabrowser.org/oma/group/A0A8V0YDC8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "serine-type endopeptidase inhibitor activity", "id": "GO:0004867", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004867", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YDC8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDC8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YDC8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDC8" } ], "pmid": "" }, { "name": "cell surface", "id": "GO:0009986", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009986", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YDC8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDC8" } ], "pmid": "" }, { "name": "caveola", "id": "GO:0005901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005901", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YDC8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDC8" } ], "pmid": "" }, { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YDC8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDC8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "blood coagulation", "id": "GO:0007596", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007596", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YDC8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDC8" } ], "pmid": "" }, { "name": "negative regulation of blood coagulation", "id": "GO:0030195", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030195", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YDC8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDC8" } ], "pmid": "" }, { "name": "cellular response to steroid hormone stimulus", "id": "GO:0071383", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071383", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YDC8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDC8" } ], "pmid": "" }, { "name": "cellular response to lipid", "id": "GO:0071396", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071396", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YDC8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDC8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 196, "end_pos": 198, "annotation": "n_glycosylation_sequon" }, { "start_pos": 239, "end_pos": 241, "annotation": "n_glycosylation_sequon" }, { "start_pos": 259, "end_pos": 261, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YDC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDC8" }, { "id": "PS50279", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50279" } ], 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"database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YEP0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEP0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YGS0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGS0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YGS0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGS0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YGT8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGT8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YGT8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGT8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLJ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLJ0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLJ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLJ0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLK3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLK3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLK3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLK3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGTQGAGRKRLPNRERLTAEDDALNQIAREAEARLAAKRAARAEAREIRMKELERQQKEIYQVQKKYYGLDTKWGDIEQWMEDSERYSRRARRNASASDEDERMSVGSRGSLRSHVEYAGAYPVAGLENERTKWKNYSKATNGYEEDMYGSSQSRKSSRASYYPDLGLPNSGYASTSQPSSQNGNWASVYDESVYSGSRRYSASSSRAPSEYSCYLGSGSRASSRASSARASPVIEERPEKDFEKGARTVSSLSAATLASLGGTSSRRGSGDTSISADTEASIREIKDSLAEVEEKYKKAMVSNAQLDNEKTNFMYQVDTLKDALLELEEQLAESRRQYEEKSKEFEREKHAHSILQFQFKEIKEALKQREEMLAKHGIIPDSDIATNGEASDVLDNEGHLDSSKTVQGTTQALKTAGDGMLGKANEVDMKNEILEDVGKREILQNSEREEHKEESEEQEVQTLHADENTKAEKMIEETDGLSTVMLPDSRFTEQIPSLTEPMSGNASSNDGSGGDGLRMETESADTAAQQPVSKEAEHGNLNPRTTENSEVGSLQGQDFESPQETHGDSDAEHELVKAAPQQEGEDVEASHALSANEVEQAADSAHDSSEMVSVQSGLPDPVLAGLLSEEVNVEGHAETLQCLEESAGNKVTEVLEKTLVESKDCTGGTADKTGGDRAGEQNEVWSAVQGQKMERDSTGLEGEESCESGAPSDPNEEGGDQAHIQPVSSEVGELALLEEQNTQEQTELKPAEKDGQEEVLIGNLEACSDPAEKQEKASESVGSANEVEGNVLHQTEPDMDSVKEMAAQETSLDPDFSDDEIEETEMQTGDVSGKGEGNRIEDLEHNTTEDLKPKAELQTVQCSEETTGDTEDEKNTSLESEAQNADKQEEGESKEESIVCHSVTSESQVDKEALKENKKESEPADHQGDGFTSVEDADSSLALKAELDENASEQLKLEGQAEEEQEDDGDAFDFDEDSEQTVETDEKCDGEEVDAQSEEDDRTNSVIRKTAQTGEAGEGSGKIETSDTLTEDDSLQHKEGNESEETELSQEEASALETDEKADVLADEDKASDPNEVEKEPGEQDLESAGCSRAESKEDLRGGRKGKGKSKDDCTMS", "length": 1118, "header": "tr|A0A8V0YDF0-1|A0A8V0YDF0_CHICK Isoform 1 of LRR binding FLII interacting protein 1 OS=Gallus gallus OX=9031 GN=LRRFIP1 PE=1 SV=1 CANONICAL=A0A8V0YDF0-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Y8D2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDF0/entry#A0A8V0Y8D2-1", "sequence": { "sequence": "MYGSSQSRKSSRIEERPEKDFEKGARTVSSLSAATLASLGGTSSRRGSGDTSISADTEASIREIKDSLAEVEEKYKKAMVSNAQLDNEKTNFMYQVDTLKDALLELEEQLAESRRQYEEKSKEFEREKHAHSILQFQFKEIKEALKQREEMLAKHGIIPDSDIATNGEASDVLDNEGHLDSSKTVQGTTQALKTAGDGMLGKANEVDMKNEILEDVGKREILQNSEREEHKEESEEQEVQTLHADENTKAEKMIEETDGLSTVMLPDSRFTEQIPSLTEPMSGNASSNDGSGGDGLRMETESADTAAQQPVSKEAEHGNLNPRTTENSEVGSLQGQDFESPQETHGDSDAEHELVKAAPQQEGEDVEASHALSANEVEQAADSAHDSSEMVSVQSGLPDPVLAGLLSEEVNVEGHAETLQCLEESAGNKVTEVLEKTLVESKDCTGGTADKTGGDRAGEQNEVWSAVQGQKMERDSTGLEGEESCESGAPSDPNEEGGDQAHIQPVSSEVGELALLEEQNTQEQTELKPAEKDGQEEVLIGNLEACSDPAEKQEKASESVGSANEVEGNVLHQTEPDMDSVKEMAAQETSLDPDFSDDEIEETEMQTGDVSGKGEGNRIEDLEHNTTEDLKPKAELQTVQCSEETTGDTEDEKNTSLESEAQNADKQEEGESKEESIVCHSVTSESQVDKEALKENKKESEPADHQGDGFTSVEDADSSLALKAELDENASEQLKLEGQAEEEQEDDGDAFDFDEDSEQTVETDEKCDGEEVDAQSEEDDRTNSVIRKTAQTGEAGEGSGKIETSDTLTEDDSLQHKEGNESEETELSQEEASALETDEKADVLADEDKASDPNEVEKEPGEQDLESAGCSRAESKEDLRGGRKGKGKSKDDCTMS", "length": 896, "header": "tr|A0A8V0Y8D2-1|A0A8V0Y8D2_CHICK Computationally mapped isoform of LRR binding FLII interacting protein 1 OS=Gallus gallus OX=9031 GN=LRRFIP1 PE=1 SV=1 CANONICAL=A0A8V0YDF0-1" }, "locus": { "chromosome": "7", "start_pos": 4770934, "end_pos": 4748870, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029232.1", "url": "https://www.ensembl.org/id/ENSGALT00010029232.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016957.1", "url": "https://www.ensembl.org/id/ENSGALP00010016957.1" } ] } }, { "isoform_ac": "A0A8V0Y8E3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDF0/entry#A0A8V0Y8E3-1", "sequence": { "sequence": "MPMEADCLSPEAQKLAEARLAAKRAARAEAREIRMKELERQQKEASDEDERMSVGSRGSLRPSEYSCYLGSGSRASSRASSARASPVIEERPEKDFEKGARTVSSLSAATLASLGGTSSRRGSGDTSISADTEASIREIKDSLAEVEEKYKKAMVSNAQLDNEKTNFMYQVDTLKDALLELEEQLAESRRQYEEKSKEFEREKHAHSILQFQFKEIKEALKQREEMLAKHGIIPDSDIATNGEASDVLDNEGHLDSSKTVQGTTQALKTAGDGMLGKANEVDMKNEILEDVGKREILQNSEREEHKEESEEQEVQTLHADENTKAEKMIEETDGLSTVMLPDSRFTEQIPSLTEPMSGNASSNDGSGGDGLRMETESADTAAQQPVSKEAEHGNLNPRTTENSEVGSLQGQDFESPQETHGDSDAEHELVKAAPQQEGEDVEASHALSANEVEQAADSAHDSSEMVSVQSGLPDPVLAGLLSEEVNVEGHAETLQCLEESAGNKVTEVLEKTLVESKDCTGGTADKTGGDRAGEQNEVWSAVQGQKMERDSTGLEGEESCESGAPSDPNEEGGDQAHIQPVSSEVGELALLEEQNTQEQTELKPAEKDGQEEVLIGNLEACSDPAEKQEKASESVGSANEVEGNVLHQTEPDMDSVKEMAAQETSLDPDFSDDEIEETEMQTGDVSGKGEGNRIEDLEHNTTEDLKPKAELQTVQCSEETTGDTEDEKNTSLESEAQNADKQEEGESKEESIVCHSVTSESQVDKEALKENKKESEPADHQGDGFTSVEDADSSLALKAELDENASEQLKLEGQAEEEQEDDGDAFDFDEDSEQTVETDEKCDGEEVDAQSEEDDRTNSVIRKTAQTGEAGEGSGKIETSDTLTEDDSLQHKEGNESEETELSQEEASALETDEKADVLADEDKASDPNEVEKEPGEQDLESAGCSRAESKEDLRGGRKGKGKSKDDCTMS", "length": 971, "header": "tr|A0A8V0Y8E3-1|A0A8V0Y8E3_CHICK Computationally mapped isoform of LRR binding FLII interacting protein 1 OS=Gallus gallus OX=9031 GN=LRRFIP1 PE=1 SV=1 CANONICAL=A0A8V0YDF0-1" }, "locus": { "chromosome": "7", "start_pos": 4795099, "end_pos": 4748870, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029248.1", "url": "https://www.ensembl.org/id/ENSGALT00010029248.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016968.1", "url": "https://www.ensembl.org/id/ENSGALP00010016968.1" } ] } }, { "isoform_ac": "A0A8V0YDD7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDF0/entry#A0A8V0YDD7-1", "sequence": { "sequence": "MEQMSIAHPRSQQASDEDERMSVGSRGSLRIEERPEKDFEKGARTVSSLSAATLASLGGTSSRRGSGDTSISADTEASIREIKDSLAEVEEKYKKAMVSNAQLDNEKTNFMYQVDTLKDALLELEEQLAESRRQYEEKSKEFEREKHAHSILQFQFKEIKEALKQREEMLAKHGIIPDSDIATNGEASDVLDNEGHLDSSKTVQGTTQALKTAGDGMLGKANEVDMKNEILEDVGKREILQNSEREEHKEESEEQEVQTLHADENTKAEKMIEETDGLSTVMLPDSRFTEQIPSLTEPMSGNASSNDGSGGDGLRMETESADTAAQQPVSKEAEHGNLNPRTTENSEVGSLQGQDFESPQETHGDSDAEHELVKAAPQQEGEDVEASHALSANEVEQAADSAHDSSEMVSVQSGLPDPVLAGLLSEEVNVEGHAETLQCLEESAGNKVTEVLEKTLVESKDCTGGTADKTGGDRAGEQNEVWSAVQGQKMERDSTGLEGEESCESGAPSDPNEEGGDQAHIQPVSSEVGELALLEEQNTQEQTELKPAEKDGQEEVLIGNLEACSDPAEKQEKASESVGSANEVEGNVLHQTEPDMDSVKEMAAQETSLDPDFSDDEIEETEMQTGDVSGKGEGNRIEDLEHNTTEDLKPKAELQTVQCSEETTGDTEDEKNTSLESEAQNADKQEEGESKEESIVCHSVTSESQVDKEALKENKKESEPADHQGDGFTSVEDADSSLALKAELDENASEQLKLEGQAEEEQEDDGDAFDFDEDSEQTVETDEKCDGEEVDAQSEEDDRTNSVIRKTAQTGEAGEGSGKIETSDTLTEDDSLQHKEGNESEETELSQEEASALETDEKADVLADEDKASDPNEVEKEPGEQDLESAGCSRAESKEDLRGGRKGKGKSKDDCTMS", "length": 914, "header": "tr|A0A8V0YDD7-1|A0A8V0YDF0_CHICK Computationally mapped isoform of LRR binding FLII interacting protein 1 OS=Gallus gallus OX=9031 GN=LRRFIP1 PE=1 SV=1 CANONICAL=A0A8V0YDF0-1" }, "locus": { "chromosome": "7", "start_pos": 4783081, "end_pos": 4748870, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029238.1", "url": "https://www.ensembl.org/id/ENSGALT00010029238.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016962.1", "url": "https://www.ensembl.org/id/ENSGALP00010016962.1" } ] } }, { "isoform_ac": "A0A8V0YDF0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDF0/entry#A0A8V0YDF0-1", "sequence": { "sequence": "MGTQGAGRKRLPNRERLTAEDDALNQIAREAEARLAAKRAARAEAREIRMKELERQQKEIYQVQKKYYGLDTKWGDIEQWMEDSERYSRRARRNASASDEDERMSVGSRGSLRSHVEYAGAYPVAGLENERTKWKNYSKATNGYEEDMYGSSQSRKSSRASYYPDLGLPNSGYASTSQPSSQNGNWASVYDESVYSGSRRYSASSSRAPSEYSCYLGSGSRASSRASSARASPVIEERPEKDFEKGARTVSSLSAATLASLGGTSSRRGSGDTSISADTEASIREIKDSLAEVEEKYKKAMVSNAQLDNEKTNFMYQVDTLKDALLELEEQLAESRRQYEEKSKEFEREKHAHSILQFQFKEIKEALKQREEMLAKHGIIPDSDIATNGEASDVLDNEGHLDSSKTVQGTTQALKTAGDGMLGKANEVDMKNEILEDVGKREILQNSEREEHKEESEEQEVQTLHADENTKAEKMIEETDGLSTVMLPDSRFTEQIPSLTEPMSGNASSNDGSGGDGLRMETESADTAAQQPVSKEAEHGNLNPRTTENSEVGSLQGQDFESPQETHGDSDAEHELVKAAPQQEGEDVEASHALSANEVEQAADSAHDSSEMVSVQSGLPDPVLAGLLSEEVNVEGHAETLQCLEESAGNKVTEVLEKTLVESKDCTGGTADKTGGDRAGEQNEVWSAVQGQKMERDSTGLEGEESCESGAPSDPNEEGGDQAHIQPVSSEVGELALLEEQNTQEQTELKPAEKDGQEEVLIGNLEACSDPAEKQEKASESVGSANEVEGNVLHQTEPDMDSVKEMAAQETSLDPDFSDDEIEETEMQTGDVSGKGEGNRIEDLEHNTTEDLKPKAELQTVQCSEETTGDTEDEKNTSLESEAQNADKQEEGESKEESIVCHSVTSESQVDKEALKENKKESEPADHQGDGFTSVEDADSSLALKAELDENASEQLKLEGQAEEEQEDDGDAFDFDEDSEQTVETDEKCDGEEVDAQSEEDDRTNSVIRKTAQTGEAGEGSGKIETSDTLTEDDSLQHKEGNESEETELSQEEASALETDEKADVLADEDKASDPNEVEKEPGEQDLESAGCSRAESKEDLRGGRKGKGKSKDDCTMS", "length": 1118, "header": "tr|A0A8V0YDF0-1|A0A8V0YDF0_CHICK Isoform 1 of LRR binding FLII interacting protein 1 OS=Gallus gallus OX=9031 GN=LRRFIP1 PE=1 SV=1 CANONICAL=A0A8V0YDF0-1" }, "locus": { "chromosome": "7", "start_pos": 4827109, "end_pos": 4748870, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029252.1", "url": "https://www.ensembl.org/id/ENSGALT00010029252.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016972.1", "url": "https://www.ensembl.org/id/ENSGALP00010016972.1" } ] } }, { "isoform_ac": "A0A8V0YEN2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDF0/entry#A0A8V0YEN2-1", "sequence": { "sequence": "MGTQGAGRKRLPNRERLTAEDDALNQIAREAEARLAAKRAARAEAREIRMKELERQQKEASDEDERMSVGSRGSLRSHVEYAGAYPVAGLENERTKWKNYSKAIEERPEKDFEKGARTVSSLSAATLASLGGTSSRRGSGDTSISADTEASIREIKDIYELKEQIQDVEGKYMQGLKEMKDSLAEVEEKYKKAMVSNAQLDNEKTNFMYQVDTLKDALLELEEQLAESRRQYEEKSKEFEREKHAHSILQFQFKEIKEALKQREEMLAKHGIIPDSDIATNGEASDVLDNEGHLDSSKTVQGTTQALKTAGDGMLGKANEVDMKNEILEDVGKREILQNSEREEHKEESEEQEVQTLHADENTKAEKMIEETDGLSTVMLPDSRFTEQIPSLTEPMSGNASSNDGSGGDGLRMETESADTAAQQPVSKEAEHGNLNPRTTENSEVGSLQGQDFESPQETHGDSDAEHELVKAAPQQEGEDVEASHALSANEVEQAADSAHDSSEMVSVQSGLPDPVLAGLLSEEVNVEGHAETLQCLEESAGNKVTEVLEKTLVESKDCTGGTADKTGGDRAGEQNEVWSAVQGQKMERDSTGLEGEESCESGAPSDPNEEGGDQAHIQPVSSEVGELALLEEQNTQEQTELKPAEKDGQEEVLIGNLEACSDPAEKQEKASESVGSANEVEGNVLHQTEPDMDSVKEMAAQETSLDPDFSDDEIEETEMQTGDVSGKGEGNRIEDLEHNTTEDLKPKAELQTVQCSEETTGDTEDEKNTSLESEAQNADKQEEGESKEESIVCHSVTSESQVDKEALKENKKESEPADHQGDGFTSVEDADSSLALKAELDENASEQLKLEGQAEEEQEDDGDAFDFDEDSEQTVETDEKCDGEEVDAQSEEDDRTNSVIRKTAQTGEAGEGSGKIETSDTLTEDDSLQHKEGNESEETELSQEEASALETDEKADVLADEDKASDPNEVEKEPGEQDLESAGCSRAESKEDLRGGRKGKGKSKDDCTMS", "length": 1011, "header": "tr|A0A8V0YEN2-1|A0A8V0YEN2_CHICK Computationally mapped isoform of LRR binding FLII interacting protein 1 OS=Gallus gallus OX=9031 GN=LRRFIP1 PE=1 SV=1 CANONICAL=A0A8V0YDF0-1" }, "locus": { "chromosome": "7", "start_pos": 4827109, "end_pos": 4748870, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029256.1", "url": "https://www.ensembl.org/id/ENSGALT00010029256.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016975.1", "url": "https://www.ensembl.org/id/ENSGALP00010016975.1" } ] } }, { "isoform_ac": "A0A8V0YEP0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDF0/entry#A0A8V0YEP0-1", "sequence": { "sequence": "MGTQGAGRKRLPNRERLTAEDDALNQIAREAEARLAAKRAARAEAREIRMKELERQQKEIEERPEKDFEKGARTVSSLSAATLASLGGTSSRRGSGDTSISADTEASIREIKDIYELKEQIQDVEGKYMQGLKEMKDSLAEVEEKYKKAMVSNAQLDNEKTNFMYQVDTLKDALLELEEQLAESRRQYEEKSKEFEREKHAHSILQFQFKEIKEALKQREEMLAKHGIIPDSDIATNGEASDVLDNEGHLDSSKTVQGTTQALKTAGDGMLGKANEVDMKNEILEDVGKREILQNSEREEHKEESEEQEVQTLHADENTKAEKMIEETDGLSTVMLPDSRFTEQIPSLTEPMSGNASSNDGSGGDGLRMETESADTAAQQPVSKEAEHGNLNPRTTENSEVGSLQGQDFESPQETHGDSDAEHELVKAAPQQEGEDVEASHALSANEVEQAADSAHDSSEMVSVQSGLPDPVLAGLLSEEVNVEGHAETLQCLEESAGNKVTEVLEKTLVESKDCTGGTADKTGGDRAGEQNEVWSAVQGQKMERDSTGLEGEESCESGAPSDPNEEGGDQAHIQPVSSEVGELALLEEQNTQEQTELKPAEKDGQEEVLIGNLEACSDPAEKQEKASESVGSANEVEGNVLHQTEPDMDSVKEMAAQETSLDPDFSDDEIEETEMQTGDVSGKGEGNRIEDLEHNTTEDLKPKAELQTVQCSEETTGDTEDEKNTSLESEAQNADKQEEGESKEESIVCHSVTSESQVDKEALKENKKESEPADHQGDGFTSVEDADSSLALKAELDENASEQLKLEGQAEEEQEDDGDAFDFDEDSEQTVETDEKCDGEEVDAQSEEDDRTNSVIRKTAQTGEAGEGSGKIETSDTLTEDDSLQHKEGNESEETELSQEEASALETDEKADVLADEDKASDPNEVEKEPGEQDLESAGCSRAESKEDLRGGRKGKGKSKDDCTMS", "length": 967, "header": "tr|A0A8V0YEP0-1|A0A8V0YEP0_CHICK Computationally mapped isoform of LRR binding FLII interacting protein 1 OS=Gallus gallus OX=9031 GN=LRRFIP1 PE=1 SV=1 CANONICAL=A0A8V0YDF0-1" }, "locus": { "chromosome": "7", "start_pos": 4827109, "end_pos": 4748870, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029267.1", "url": "https://www.ensembl.org/id/ENSGALT00010029267.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016985.1", "url": "https://www.ensembl.org/id/ENSGALP00010016985.1" } ] } }, { "isoform_ac": "A0A8V0YGS0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDF0/entry#A0A8V0YGS0-1", "sequence": { "sequence": "MEQMSIAHPRSQQEDSERYSRRARRNASASDEDERMSVGSRGSLRIEERPEKDFEKGARTVSSLSAATLASLGGTSSRRGSGDTSISADTEASIREIKDSLAEVEEKYKKAMVSNAQLDNEKTNFMYQVDTLKDALLELEEQLAESRRQYEEKSKEFEREKHAHSILQFQFKEIKEALKQREEMLAKHGIIPDSDIATNGEASDVLDNEGHLDSSKTVQGTTQALKTAGDGMLGKANEVDMKNEILEDVGKREILQNSEREEHKEESEEQEVQTLHADENTKAEKMIEETDGLSTVMLPDSRFTEQIPSLTEPMSGNASSNDGSGGDGLRMETESADTAAQQPVSKEAEHGNLNPRTTENSEVGSLQGQDFESPQETHGDSDAEHELVKAAPQQEGEDVEASHALSANEVEQAADSAHDSSEMVSVQSGLPDPVLAGLLSEEVNVEGHAETLQCLEESAGNKVTEVLEKTLVESKDCTGGTADKTGGDRAGEQNEVWSAVQGQKMERDSTGLEGEESCESGAPSDPNEEGGDQAHIQPVSSEVGELALLEEQNTQEQTELKPAEKDGQEEVLIGNLEACSDPAEKQEKASESVGSANEVEGNVLHQTEPDMDSVKEMAAQETSLDPDFSDDEIEETEMQTGDVSGKGEGNRIEDLEHNTTEDLKPKAELQTVQCSEETTGDTEDEKNTSLESEAQNADKQEEGESKEESIVCHSVTSESQVDKEALKENKKESEPADHQGDGFTSVEDADSSLALKAELDENASEQLKLEGQAEEEQEDDGDAFDFDEDSEQTVETDEKCDGEEVDAQSEEDDRTNSVIRKTAQTGEAGEGSGKIETSDTLTEDDSLQHKEGNESEETELSQEEASALETDEKADVLADEDKASDPNEVEKEPGEQDLESAGCSRAESKEDLRGGRKGKGKSKDDCTMS", "length": 929, "header": "tr|A0A8V0YGS0-1|A0A8V0YGS0_CHICK Computationally mapped isoform of LRR binding FLII interacting protein 1 OS=Gallus gallus OX=9031 GN=LRRFIP1 PE=1 SV=1 CANONICAL=A0A8V0YDF0-1" }, "locus": { "chromosome": "7", "start_pos": 4783081, "end_pos": 4748870, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029235.1", "url": "https://www.ensembl.org/id/ENSGALT00010029235.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016960.1", "url": "https://www.ensembl.org/id/ENSGALP00010016960.1" } ] } }, { "isoform_ac": "A0A8V0YGT8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDF0/entry#A0A8V0YGT8-1", "sequence": { "sequence": "MGTQGAGRKRLPNRERLTAEDDALNQIAREAEARLAAKRAARAEAREIRMKELERQQKEASDEDERMSVGSRGSLRAGLENERTKWKNYSKAIEERPEKDFEKGARTVSSLSAATLASLGGTSSRRGSGDTSISADTEASIREIKDSLAEVEEKYKKAMVSNAQLDNEKTNFMYQVDTLKDALLELEEQLAESRRQYEEKSKEFEREKHAHSILQFQFKEIKEALKQREEMLAKHGIIPDSDIATNGEASDVLDNEGHLDSSKTVQGTTQALKTAGDGMLGKANEVDMKNEILEDVGKREILQNSEREEHKEESEEQEVQTLHADENTKAEKMIEETDGLSTVMLPDSRFTEQIPSLTEPMSGNASSNDGSGGDGLRMETESADTAAQQPVSKEAEHGNLNPRTTENSEVGSLQGQDFESPQETHGDSDAEHELVKAAPQQEGEDVEASHALSANEVEQAADSAHDSSEMVSVQSGLPDPVLAGLLSEEVNVEGHAETLQCLEESAGNKVTEVLEKTLVESKDCTGGTADKTGGDRAGEQNEVWSAVQGQKMERDSTGLEGEESCESGAPSDPNEEGGDQAHIQPVSSEVGELALLEEQNTQEQTELKPAEKDGQEEVLIGNLEACSDPAEKQEKASESVGSANEVEGNVLHQTEPDMDSVKEMAAQETSLDPDFSDDEIEETEMQTGDVSGKGEGNRIEDLEHNTTEDLKPKAELQTVQCSEETTGDTEDEKNTSLESEAQNADKQEEGESKEESIVCHSVTSESQVDKEALKENKKESEPADHQGDGFTSVEDADSSLALKAELDENASEQLKLEGQAEEEQEDDGDAFDFDEDSEQTVETDEKCDGEEVDAQSEEDDRTNSVIRKTAQTGEAGEGSGKIETSDTLTEDDSLQHKEGNESEETELSQEEASALETDEKADVLADEDKASDPNEVEKEPGEQDLESAGCSRAESKEDLRGGRKGKGKSKDDCTMS", "length": 976, "header": "tr|A0A8V0YGT8-1|A0A8V0YGT8_CHICK Computationally mapped isoform of LRR binding FLII interacting protein 1 OS=Gallus gallus OX=9031 GN=LRRFIP1 PE=1 SV=1 CANONICAL=A0A8V0YDF0-1" }, "locus": { "chromosome": "7", "start_pos": 4827109, "end_pos": 4748870, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029263.1", "url": "https://www.ensembl.org/id/ENSGALT00010029263.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016981.1", "url": "https://www.ensembl.org/id/ENSGALP00010016981.1" } ] } }, { "isoform_ac": "A0A8V0YLJ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDF0/entry#A0A8V0YLJ0-1", "sequence": { "sequence": "MEQMSIAHPRSQQIEERPEKDFEKGARTVSSLSAATLASLGGTSSRRGSGDTSISADTEASIREIKDSLAEVEEKYKKAMVSNAQLDNEKTNFMYQVDTLKDALLELEEQLAESRRQYEEKSKEFEREKHAHSILQFQFKEIKEALKQREEMLAKHGIIPDSDIATNGEASDVLDNEGHLDSSKTVQGTTQALKTAGDGMLGKANEVDMKNEILEDVGKREILQNSEREEHKEESEEQEVQTLHADENTKAEKMIEETDGLSTVMLPDSRFTEQIPSLTEPMSGNASSNDGSGGDGLRMETESADTAAQQPVSKEAEHGNLNPRTTENSEVGSLQGQDFESPQETHGDSDAEHELVKAAPQQEGEDVEASHALSANEVEQAADSAHDSSEMVSVQSGLPDPVLAGLLSEEVNVEGHAETLQCLEESAGNKVTEVLEKTLVESKDCTGGTADKTGGDRAGEQNEVWSAVQGQKMERDSTGLEGEESCESGAPSDPNEEGGDQAHIQPVSSEVGELALLEEQNTQEQTELKPAEKDGQEEVLIGNLEACSDPAEKQEKASESVGSANEVEGNVLHQTEPDMDSVKEMAAQETSLDPDFSDDEIEETEMQTGDVSGKGEGNRIEDLEHNTTEDLKPKAELQTVQCSEETTGDTEDEKNTSLESEAQNADKQEEGESKEESIVCHSVTSESQVDKEALKENKKESEPADHQGDGFTSVEDADSSLALKAELDENASEQLKLEGQAEEEQEDDGDAFDFDEDSEQTVETDEKCDGEEVDAQSEEDDRTNSVIRKTAQTGEAGEGSGKIETSDTLTEDDSLQHKEGNESEETELSQEEASALETDEKADVLADEDKASDPNEVEKEPGEQDLESAGCSRAESKEDLRGGRKGKGKSKDDCTMS", "length": 897, "header": "tr|A0A8V0YLJ0-1|A0A8V0YLJ0_CHICK Computationally mapped isoform of LRR binding FLII interacting protein 1 OS=Gallus gallus OX=9031 GN=LRRFIP1 PE=1 SV=1 CANONICAL=A0A8V0YDF0-1" }, "locus": { "chromosome": "7", "start_pos": 4783081, "end_pos": 4748870, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029242.1", "url": "https://www.ensembl.org/id/ENSGALT00010029242.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016964.1", "url": "https://www.ensembl.org/id/ENSGALP00010016964.1" } ] } }, { "isoform_ac": "A0A8V0YLK3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDF0/entry#A0A8V0YLK3-1", "sequence": { "sequence": "MGTQGAGRKRLPNRERLTAEDDALNQIAREAEARLAAKRAARAEAREIRMKELERQQKEASDEDERMSVGSRGSLRIEERPEKDFEKGARTVSSLSAATLASLGGTSSRRGSGDTSISADTEASIREIKDIYELKEQIQDVEGKYMQGLKEMKDSLAEVEEKYKKAMVSNAQLDNEKTNFMYQVDTLKDALLELEEQLAESRRQYEEKSKEFEREKHAHSILQFQFKEIKEALKQREEMLAKHGIIPDSDIATNGEASDVLDNEGHLDSSKTVQGTTQALKTAGDGMLGKANEVDMKNEILEDVGKREILQNSEREEHKEESEEQEVQTLHADENTKAEKMIEETDGLSTVMLPDSRFTEQIPSLTEPMSGNASSNDGSGGDGLRMETESADTAAQQPVSKEAEHGNLNPRTTENSEVGSLQGQDFESPQETHGDSDAEHELVKAAPQQEGEDVEASHALSANEVEQAADSAHDSSEMVSVQSGLPDPVLAGLLSEEVNVEGHAETLQCLEESAGNKVTEVLEKTLVESKDCTGGTADKTGGDRAGEQNEVWSAVQGQKMERDSTGLEGEESCESGAPSDPNEEGGDQAHIQPVSSEVGELALLEEQNTQEQTELKPAEKDGQEEVLIGNLEACSDPAEKQEKASESVGSANEVEGNVLHQTEPDMDSVKEMAAQETSLDPDFSDDEIEETEMQTGDVSGKGEGNRIEDLEHNTTEDLKPKAELQTVQCSEETTGDTEDEKNTSLESEAQNADKQEEGESKEESIVCHSVTSESQVDKEALKENKKESEPADHQGDGFTSVEDADSSLALKAELDENASEQLKLEGQAEEEQEDDGDAFDFDEDSEQTVETDEKCDGEEVDAQSEEDDRTNSVIRKTAQTGEAGEGSGKIETSDTLTEDDSLQHKEGNESEETELSQEEASALETDEKADVLADEDKASDPNEVEKEPGEQDLESAGCSRAESKEDLRGGRKGKGKSKDDCTMS", "length": 984, "header": "tr|A0A8V0YLK3-1|A0A8V0YLK3_CHICK Computationally mapped isoform of LRR binding FLII interacting protein 1 OS=Gallus gallus OX=9031 GN=LRRFIP1 PE=1 SV=1 CANONICAL=A0A8V0YDF0-1" }, "locus": { "chromosome": "7", "start_pos": 4827109, "end_pos": 4748870, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029261.1", "url": "https://www.ensembl.org/id/ENSGALT00010029261.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016979.1", "url": "https://www.ensembl.org/id/ENSGALP00010016979.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YDF0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDF0" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YDF0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDF0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YDF0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDF0" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YDF0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDF0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1042, "end_pos": 1044, "annotation": "n_glycosylation_sequon" }, { "start_pos": 136, "end_pos": 138, "annotation": "n_glycosylation_sequon" }, { "start_pos": 506, "end_pos": 508, "annotation": "n_glycosylation_sequon" }, { "start_pos": 847, "end_pos": 849, "annotation": "n_glycosylation_sequon" }, { "start_pos": 876, "end_pos": 878, "annotation": "n_glycosylation_sequon" }, { "start_pos": 94, "end_pos": 96, "annotation": "n_glycosylation_sequon" }, { "start_pos": 951, "end_pos": 953, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1042, "end_pos": 1044 }, { "start_pos": 136, "end_pos": 138 }, { "start_pos": 506, "end_pos": 508 }, { "start_pos": 847, "end_pos": 849 }, { "start_pos": 876, "end_pos": 878 }, { "start_pos": 94, "end_pos": 96 }, { "start_pos": 951, "end_pos": 953 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YDE1-1", "uniprot_ac": "A0A8V0YDE1", "uniprot_id": "A0A8V0YDE1_CHICK", "mass": { "chemical_mass": 52756.0, "monoisotopic_mass": 52756.0 }, "refseq": { "ac": "XP_015142966", "name": "cystine/glutamate transporter isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015142966" }, "gene_names": [ { "name": "CGTL", "type": "recommended", "evidence": [ { "id": "A0A8V0YDE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDE1" } ] }, { "name": "CGTL", "type": "synonym", "evidence": [ { "id": "XP_015142966", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015142966" } ] } ], "protein_names": [ { "name": "Cystine/glutamate transporter", "type": "recommended", "evidence": [ { "id": "A0A8V0YDE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDE1/entry#names_and_taxonomy" } ] }, { "name": "cystine/glutamate transporter isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015142966", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015142966" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015142966.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015142966", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015142966" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YDE1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDE1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CGTL", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDE1", "locus": {} } ], "crossref": [ { "id": "A0A8V0YDE1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YDE1", "database": "AlphaFoldDB", "categories": [] }, { "id": "418109", "url": "https://www.ncbi.nlm.nih.gov/gene/418109", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002293", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002293", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050598", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050598", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ARDKAWP", "url": "https://omabrowser.org/oma/group/ARDKAWP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YDE1", "url": "https://www.orthodb.org/?gene=A0A8V0YDE1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YJ10", "url": "https://www.orthodb.org/?gene=A0A8V0YJ10", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11785", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11785", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11785:SF533", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11785:SF533", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13520", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13520", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015142966", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015142966", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YDE1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDE1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YDE1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDE1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJ10", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ10", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJ10-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ10-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGKHKKKEEAVFLRKKITLLRAFSLLIGSMVGSGIFISPKGVLKNSGTVGFSLVVWFACGLLSMFGALCYAELGTRITKSGGHYIYILETLGPLPSFLFLWAEFFAIRPANSAVVSLAFGRYLLEPFFAPCAAPVPAVKLVSLLGYYAVLTLNSWSVTWSARLQTALSVVKLLALMLIIVPGMMLLAQGHTKNFQDAFDRQSLVPDKLPLAFYAGMFAYSGWFQTSFVREELVRPERNIPLAVIVSVITVIVGYMLTNISYYTALGTQDVLASPAVAVSFVQQACTNLISVVPVLVALSCFGTMNGGILTFSRTLFVASREGQWPPLFSMIHIRRHTPLPAVMLMFPLVTAMVCIGDIYHLLNFFSFSRWLFIGLATLGLIVHRYRHPELQSPFKVPLFVPVSFTIICLFTVAMSIYSDPVNISIGCTMVLSGFPVYYLVIQRKMSNRCHRLLYYLTHKLQLLLEVVQQEIKTY", "length": 474, "header": "tr|A0A8V0YDE1-1|A0A8V0YDE1_CHICK Isoform 1 of Cystine/glutamate transporter OS=Gallus gallus OX=9031 GN=CGTL PE=4 SV=1 CANONICAL=A0A8V0YDE1-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YDE1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDE1/entry#A0A8V0YDE1-1", "sequence": { "sequence": "MGKHKKKEEAVFLRKKITLLRAFSLLIGSMVGSGIFISPKGVLKNSGTVGFSLVVWFACGLLSMFGALCYAELGTRITKSGGHYIYILETLGPLPSFLFLWAEFFAIRPANSAVVSLAFGRYLLEPFFAPCAAPVPAVKLVSLLGYYAVLTLNSWSVTWSARLQTALSVVKLLALMLIIVPGMMLLAQGHTKNFQDAFDRQSLVPDKLPLAFYAGMFAYSGWFQTSFVREELVRPERNIPLAVIVSVITVIVGYMLTNISYYTALGTQDVLASPAVAVSFVQQACTNLISVVPVLVALSCFGTMNGGILTFSRTLFVASREGQWPPLFSMIHIRRHTPLPAVMLMFPLVTAMVCIGDIYHLLNFFSFSRWLFIGLATLGLIVHRYRHPELQSPFKVPLFVPVSFTIICLFTVAMSIYSDPVNISIGCTMVLSGFPVYYLVIQRKMSNRCHRLLYYLTHKLQLLLEVVQQEIKTY", "length": 474, "header": "tr|A0A8V0YDE1-1|A0A8V0YDE1_CHICK Isoform 1 of Cystine/glutamate transporter OS=Gallus gallus OX=9031 GN=CGTL PE=4 SV=1 CANONICAL=A0A8V0YDE1-1" }, "locus": { "chromosome": "1", "start_pos": 56694945, "end_pos": 56682128, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032019.1", "url": "https://www.ensembl.org/id/ENSGALT00010032019.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018809.1", "url": "https://www.ensembl.org/id/ENSGALP00010018809.1" } ] } }, { "isoform_ac": "A0A8V0YJ10-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDE1/entry#A0A8V0YJ10-1", "sequence": { "sequence": "MGKHKKKEEAVFLRKKITLLRAFSLLIGSMVGSGIFISPKGVLKNSGTVGFSLVVWFACGLLSMFGALCYAELGTRITKSGGHYIYILETLGPLPSFLFLWAEFFAIRPANSAVVSLAFGRYLLEPFFAPCAAPVPAVKLVSLLGYYAVLTLNSWSVTWSARLQTALSVVKLLALMLIIVPGMMLLAQGHTKNFQDAFDRQSLVPDKLPLAFYAGMFAYSGWFQTSFVREELVRPERNIPLAVIVSVITVIVGYMLTNISYYTALGTQDVLASPAVAVSFVQQACTNLISVVPVLVALSCFGTMNGGILTFSRTLFVASREGQWPPLFSMIHIRRHTPLPAVMLMFPLVTAMVCIGDIYHLLNFFSFSRWLFIGLATLGLIVHRYRHPELQSPFKVPLFVPVSFTIICLFTVAMSIYSDPVNISIGCTMVLSGFPVYYLVIQRKMSNRCHRLL", "length": 453, "header": "tr|A0A8V0YJ10-1|A0A8V0YJ10_CHICK Computationally mapped isoform of Cystine/glutamate transporter OS=Gallus gallus OX=9031 GN=CGTL PE=4 SV=1 CANONICAL=A0A8V0YDE1-1" }, "locus": { "chromosome": "1", "start_pos": 56694945, "end_pos": 56682912, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032018.1", "url": 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"ALPK2", "type": "synonym", "evidence": [ { "id": "XP_046761540", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046761540" } ] } ], "protein_names": [ { "name": "non-specific serine/threonine protein kinase", "type": "recommended", "evidence": [ { "id": "A0A8V0YDH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDH4/entry#names_and_taxonomy" } ] }, { "name": "2.7.11.1", "type": "synonym", "evidence": [ { "id": "A0A8V0YDH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDH4/entry#names_and_taxonomy" } ] }, { "name": "alpha-protein kinase 2", "type": "synonym", "evidence": [ { "id": "XP_046761540", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046761540" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052572.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_046761540", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046761540" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YDH4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDH4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ALPK2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDH4", "locus": { "chromosome": "Z", "start_pos": 1096622, "end_pos": 1125646, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010010330", "url": "https://www.ensembl.org/id/ENSGALG00010010330" } ] } } ], "crossref": [ { "id": "cd16974", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16974", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "426853", "url": "https://www.ncbi.nlm.nih.gov/gene/426853", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004166", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004166", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011009", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011009", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013098", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013098", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:426853", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:426853", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CMEPRTE", "url": "https://omabrowser.org/oma/group/CMEPRTE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YDH4", "url": "https://www.orthodb.org/?gene=A0A8V0YDH4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47091", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47091", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47091:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47091:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02816", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02816", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07679", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07679", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_046761540", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046761540", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "17989", "url": "https://www.rhea-db.org/rhea/17989", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "46608", "url": "https://www.rhea-db.org/rhea/46608", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YDH4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDH4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YDH4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDH4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEDDMDVKNIFKTQENSCCVRDVSQNGDDLNNFNSMVCTTAGKTEKNCSRPLHSHPADPFTDCTDNCCLHVEDFVSGHSLADVQACEKTELHRSLPRNALLSERDSPIVNLNYFVKGDSENSDSILEIHPSVSDDRYDDDLEYLECSDVLTVHDNEIWEKKLQFLLESDDEDDLKLSKDCDGCAYFLSEMPCLFQVSDNITPMDTTIGLCGHQSKFKGVNIRRDPSTYSQSTLQTEMTLTVGHHREKTTGLKDKENCKVPVAPAALENDYLKMEEKNNGSVQPAADFSTDKPQNGDNAHAMADSCARDTGAALTNLPSETMTEGNMDADLVDESSLTPEEGRRNLLEENARHPVSTLTESLRRNLLKLLNPKELCRYVSNIGQSFQTAAEIESSALFPSQEGVLSTQICEETESLQMQAGLCHTEEADKDPRWEQKKTWGLCEQNQVPHGNVSPRKQGDSFKICAQNCDRPCMEPETEKEGIFTTCKCVGVIHSASEALCTEKTLQGKNANVQTYSQHDAPCDKRESCHQQVFWEQGTDISSKDNKPKNDTSPFPLWDTDSVPDKQECLCAVLSSAKLCDEPRGRGQRYDFDSHDSNDTDTLCSISSDALLFEANPQSVLESGEPGCKGDADLAAVHDKLWKLFHEDDSDCQIPFENCGITSLEMRPADTRVAEMNLLQETCSDHPVPQNVIEQQEPITQPPTGERTEKEDCSVSNILLKTDEAYNSVSRGNVFLTEADGTCLSSSSGNKAETVSVCTPKDVLNTEVCLEQKPSQTITDNNGSIRMTVYWEGKLTVNNALQTRDAESRRVLKSAQSSNLASDNENSAYVSDRSHWTTGQLLHTEQNIPLVSKTISKNTDEDDCHFKGCYPARNKLTYFPEGKFVLPSNSSDENTLQFAHGEHASVNTTGKSCEDDLHEKRNHSDLNAQNGTHSGSYHLLKNYDCQDVPVVSNAQKYSYLMKLPNLINTPGNITCRNLPHNTYQMTELQEQEIVFTPSSENPSLTDFCAEVPKYEPSKTEKEQRGICIGDEQRAETSCGSGVRDVSESQPAASPPSVSEQQVFFPDNTFKSDEELKPDSSNNYTYASGNVTSASVSTPLPRMVQNEYSSIASDDYRDVSNQMDIQQVNVGETSPFVIPVNQSKGALHSVSAMGSSGTGSQAQAECTQTAVKVDEKLCKLGTFCRALQDEFHNAPEASKERAILCENKQEIRRTIEYSPDDAEVKFPLHPSTSSKAQRQISNNITKQSSPNLISSSKLTEFNYSIKSTRCHKDGEVMTSGTAVGGLVGLPQGDNLYFQRQPPCSSTQPYSLALTAYDPFPVDAKRLESQERSKSCQTLPTVAEPEPIKCKQHIARSGNVATGAKKKLPPATLSKKPRLAERENVSKDPSCVKSEANIIYKENKKEQRKLISKKDSKAPKLLKKIQAELFPDCSGNIKLCCQFGDIHGDSTITWTKDSKLLAQLQRNAQDDSPVSLAIAKASNKDQGMYYCCLSNIYGRVTAEFNLTSEVLEHLSSFQHFEGVEEIEFMQLMFREDFICDSYFGGNLHGILATEELHFGEGMHRKAFRSKVMQGLVPVFSPGHPCVLKVHNAITYGTKSKDDLVQRNYKLALQECYVQNTAREYAKIYAAEAEPLEGFGEAPEIIPIFLVHRPANNIPYATVEEELIGEFVKYSVKDGKEINFLRRDSEAGQKCCTFQHWVYEKTNGNLLVTDLQGVGMKLTDVGIATLAKGYKGFKGNCSISFIEQFRALHQCNKYCEMLGLKSLRSTHQKQRKPTSMKSKTLPSSPTVKKTVCKKAREPRDFTSSEH", "length": 1806, "header": "tr|A0A8V0YDH4-1|A0A8V0YDH4_CHICK Isoform 1 of non-specific serine/threonine protein kinase OS=Gallus gallus OX=9031 GN=ALPK2 PE=3 SV=1 CANONICAL=A0A8V0YDH4-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YDH4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDH4/entry#A0A8V0YDH4-1", "sequence": { "sequence": "MEDDMDVKNIFKTQENSCCVRDVSQNGDDLNNFNSMVCTTAGKTEKNCSRPLHSHPADPFTDCTDNCCLHVEDFVSGHSLADVQACEKTELHRSLPRNALLSERDSPIVNLNYFVKGDSENSDSILEIHPSVSDDRYDDDLEYLECSDVLTVHDNEIWEKKLQFLLESDDEDDLKLSKDCDGCAYFLSEMPCLFQVSDNITPMDTTIGLCGHQSKFKGVNIRRDPSTYSQSTLQTEMTLTVGHHREKTTGLKDKENCKVPVAPAALENDYLKMEEKNNGSVQPAADFSTDKPQNGDNAHAMADSCARDTGAALTNLPSETMTEGNMDADLVDESSLTPEEGRRNLLEENARHPVSTLTESLRRNLLKLLNPKELCRYVSNIGQSFQTAAEIESSALFPSQEGVLSTQICEETESLQMQAGLCHTEEADKDPRWEQKKTWGLCEQNQVPHGNVSPRKQGDSFKICAQNCDRPCMEPETEKEGIFTTCKCVGVIHSASEALCTEKTLQGKNANVQTYSQHDAPCDKRESCHQQVFWEQGTDISSKDNKPKNDTSPFPLWDTDSVPDKQECLCAVLSSAKLCDEPRGRGQRYDFDSHDSNDTDTLCSISSDALLFEANPQSVLESGEPGCKGDADLAAVHDKLWKLFHEDDSDCQIPFENCGITSLEMRPADTRVAEMNLLQETCSDHPVPQNVIEQQEPITQPPTGERTEKEDCSVSNILLKTDEAYNSVSRGNVFLTEADGTCLSSSSGNKAETVSVCTPKDVLNTEVCLEQKPSQTITDNNGSIRMTVYWEGKLTVNNALQTRDAESRRVLKSAQSSNLASDNENSAYVSDRSHWTTGQLLHTEQNIPLVSKTISKNTDEDDCHFKGCYPARNKLTYFPEGKFVLPSNSSDENTLQFAHGEHASVNTTGKSCEDDLHEKRNHSDLNAQNGTHSGSYHLLKNYDCQDVPVVSNAQKYSYLMKLPNLINTPGNITCRNLPHNTYQMTELQEQEIVFTPSSENPSLTDFCAEVPKYEPSKTEKEQRGICIGDEQRAETSCGSGVRDVSESQPAASPPSVSEQQVFFPDNTFKSDEELKPDSSNNYTYASGNVTSASVSTPLPRMVQNEYSSIASDDYRDVSNQMDIQQVNVGETSPFVIPVNQSKGALHSVSAMGSSGTGSQAQAECTQTAVKVDEKLCKLGTFCRALQDEFHNAPEASKERAILCENKQEIRRTIEYSPDDAEVKFPLHPSTSSKAQRQISNNITKQSSPNLISSSKLTEFNYSIKSTRCHKDGEVMTSGTAVGGLVGLPQGDNLYFQRQPPCSSTQPYSLALTAYDPFPVDAKRLESQERSKSCQTLPTVAEPEPIKCKQHIARSGNVATGAKKKLPPATLSKKPRLAERENVSKDPSCVKSEANIIYKENKKEQRKLISKKDSKAPKLLKKIQAELFPDCSGNIKLCCQFGDIHGDSTITWTKDSKLLAQLQRNAQDDSPVSLAIAKASNKDQGMYYCCLSNIYGRVTAEFNLTSEVLEHLSSFQHFEGVEEIEFMQLMFREDFICDSYFGGNLHGILATEELHFGEGMHRKAFRSKVMQGLVPVFSPGHPCVLKVHNAITYGTKSKDDLVQRNYKLALQECYVQNTAREYAKIYAAEAEPLEGFGEAPEIIPIFLVHRPANNIPYATVEEELIGEFVKYSVKDGKEINFLRRDSEAGQKCCTFQHWVYEKTNGNLLVTDLQGVGMKLTDVGIATLAKGYKGFKGNCSISFIEQFRALHQCNKYCEMLGLKSLRSTHQKQRKPTSMKSKTLPSSPTVKKTVCKKAREPRDFTSSEH", "length": 1806, "header": "tr|A0A8V0YDH4-1|A0A8V0YDH4_CHICK Isoform 1 of non-specific serine/threonine protein kinase OS=Gallus gallus OX=9031 GN=ALPK2 PE=3 SV=1 CANONICAL=A0A8V0YDH4-1" }, "locus": { "chromosome": "Z", "start_pos": 1125447, "end_pos": 1097013, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010024700.1", "url": "https://www.ensembl.org/id/ENSGALT00010024700.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010014012.1", "url": "https://www.ensembl.org/id/ENSGALP00010014012.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "gga:426853", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:426853", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YDH4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDH4" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YDH4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDH4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "basolateral plasma membrane", "id": "GO:0016323", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016323", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YDH4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDH4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "heart morphogenesis", "id": "GO:0003007", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003007", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YDH4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDH4" } ], "pmid": "" }, { "name": "regulation of apoptotic process", "id": "GO:0042981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042981", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YDH4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDH4" } ], "pmid": "" }, { "name": "cardiac muscle cell development", "id": "GO:0055013", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055013", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YDH4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDH4" } ], "pmid": "" }, { "name": "establishment of cell polarity", "id": "GO:0030010", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030010", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YDH4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDH4" } ], "pmid": "" }, { "name": "negative regulation of Wnt signaling pathway involved in heart development", "id": "GO:0003308", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003308", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YDH4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDH4" } ], "pmid": "" }, { "name": "epicardium morphogenesis", "id": "GO:1905223", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905223", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YDH4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDH4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1081, "end_pos": 1083, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1088, "end_pos": 1090, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1139, "end_pos": 1141, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1241, "end_pos": 1243, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1260, "end_pos": 1262, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1381, "end_pos": 1383, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1502, "end_pos": 1504, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1736, "end_pos": 1738, "annotation": "n_glycosylation_sequon" }, { "start_pos": 199, "end_pos": 201, "annotation": "n_glycosylation_sequon" }, { "start_pos": 278, "end_pos": 280, "annotation": "n_glycosylation_sequon" }, { "start_pos": 451, "end_pos": 453, "annotation": "n_glycosylation_sequon" }, { "start_pos": 47, "end_pos": 49, "annotation": "n_glycosylation_sequon" }, { "start_pos": 549, "end_pos": 551, "annotation": "n_glycosylation_sequon" }, { "start_pos": 597, "end_pos": 599, "annotation": "n_glycosylation_sequon" }, { "start_pos": 781, "end_pos": 783, "annotation": "n_glycosylation_sequon" }, { "start_pos": 888, "end_pos": 890, "annotation": "n_glycosylation_sequon" }, { "start_pos": 906, "end_pos": 908, "annotation": "n_glycosylation_sequon" }, { "start_pos": 921, "end_pos": 923, "annotation": "n_glycosylation_sequon" }, { "start_pos": 929, "end_pos": 931, "annotation": "n_glycosylation_sequon" }, { "start_pos": 971, "end_pos": 973, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "17989", "name": "", "equation": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q6U1I9-1", "A0A8V0XNJ2-1", "A0A8V0ZUL0-1", "A0A8V0ZT63-1", "A0A8V1ACW2-1", "A0A8V0Z1X0-1", "A0A8V0YHN2-1", "A0A8V0YMN5-1", "A0A8V0Z807-1", "A0A8V0Z930-1", "A0A8V0YFR6-1", "A0A1D5P0M9-1", "A0A8V0ZBN6-1", "A0A3Q2U9U9-1", "A0A8V0YXZ5-1", "A0A8V0ZSP4-1", "A0A8V0ZXQ9-1", "A0A8V0ZZV3-1", "A0A8V1ADF0-1", "A0A8V0ZFT3-1", "A0A8V0ZA45-1", "A0A8V0ZB33-1", "A0A8V0ZD70-1", "A0A8V0Z8T4-1", "R4GIN8-1", "A0A8V0ZK64-1", "A0A8V0ZC16-1", "A0A8V0ZWW1-1", "E1BY69-1", "A0A8V0ZDW9-1", "A0A8V0ZKA2-1", "A0A3Q3B2F1-1", "F1P356-1", "A0A8V1AHA8-1", "Q8QFP8-1", "F1P011-1", "A0A8V0YKK3-1", "A0A1D5NWT4-1", "A0A1D5PMQ7-1", "E1BWA3-1", "F1NVF2-1", "A0A1D5PXN4-1", "A0A3Q2TY19-1", "A0A3Q2U592-1", "A0A8V0XCV5-1", "A0A1D5P8A9-1", "A0A1D5PMG2-1", "A0A8V0X1Q7-1", "A0A8V0Y935-1", "A0A8V0YM96-1", "A0A8V0YF83-1", "A0A8V0YJP9-1", "A0A8V1AKW4-1", "A0A8V0ZSB4-1", "F1NBT0-1", "P18652-1", "P21868-1", "P21869-1", "P53666-1", "P79996-1", "Q5F3W3-1", "Q5ZJS0-1", "Q5ZKN1-1", "Q5ZLL1-1", "A0A8V0XCS0-1", "A0A8V0XNK8-1", "A0A8V0XLV6-1", "A0A8V0XDR5-1", "E1BYH2-1", "E1BQN6-1", "A0A8V0XU71-1", "Q5ZJH6-1", "A0A8V0Y3D1-1", "A0A8V0Y7C3-1", "A0A8V0YCY4-1", "A0A8V0YIV6-1", "A0A8V0YK18-1", "A0A8V0YM22-1", "A0A8V0YTN5-1", "A0A8V0YTP2-1", "Q5F3L1-1", "A0A8V0Y3L2-1", "A0A8V0YCY8-1", "A0A8V0Y9Q1-1", "A0A8V0ZD48-1", "A0A8V0ZD60-1", "A0A8V0ZBZ2-1", "A0A8V0Z9J0-1", "A0A8V1ABF3-1", "Q8AYC9-1", "A0A8V0Z927-1", "A0A8V1A2T9-1", "Q5ZKI0-1", "Q7T0B1-1", "P10741-1", "A0A8V0YFH4-1", "E1C848-1", "A0A8V0X8M1-1", "E1BW33-1", "A0A8V0Z283-1", "A0A8V0Z157-1", "A0A3Q2U4X3-1", "A0A8V0XW11-1", "E1BUG0-1", "A0A8V1ABP4-1", "A0A8V1AJA4-1", "A0A8V1AEH4-1", "F1NJH1-1", "A0A8V1AMK5-1", "A0A3Q2TRY2-1", "A0A8V0X3D6-1", "A0A1D5PD64-1", 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"https://www.uniprot.org/uniprotkb/A0A8V0XB58" } ] } ] }, { "uniprot_ac": "A0A8V0XBZ0", "gene_name": "STK32C", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XBZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XBZ0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XBZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XBZ0" } ] } ] }, { "uniprot_ac": "A0A8V0XCS0", "gene_name": "PRKG2", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XCS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCS0" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "A0A8V0XCS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCS0" } ] } ] }, { 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[ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XDR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XDR5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XDR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XDR5" } ] } ] }, { "uniprot_ac": "A0A8V0XE48", "gene_name": "ROCK2", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XE48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XE48" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "A0A8V0XE48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XE48" } ] } ] }, { "uniprot_ac": "A0A8V0XEA3", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XEA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEA3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XEA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEA3" } ] } ] }, { "uniprot_ac": "A0A8V0XFW1", "gene_name": "SGK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XFW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XFW1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XFW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XFW1" } ] } ] }, { "uniprot_ac": "A0A8V0XFX2", "gene_name": "NEK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XFX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XFX2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XFX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XFX2" } ] } ] }, { "uniprot_ac": "A0A8V0XG21", "gene_name": "LOC107050335", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XG21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XG21" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XG21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XG21" } ] } ] }, { "uniprot_ac": "A0A8V0XI18", "gene_name": "ATM", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XI18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XI18" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XI18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XI18" } ] } ] }, { "uniprot_ac": "A0A8V0XKG0", "gene_name": "NEK9", "activity": [ { "ec_number": "2.7.11.38", "activity": "L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XKG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XKG0" } ] }, { "ec_number": "2.7.11.38", "activity": "", "evidence": [ { "id": "A0A8V0XKG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XKG0" } ] } ] }, { "uniprot_ac": "A0A8V0XLV6", "gene_name": "MAPK10", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XLV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XLV6" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0XLV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XLV6" } ] } ] }, { "uniprot_ac": "A0A8V0XMT1", "gene_name": "MOS", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XMT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMT1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XMT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMT1" } ] } ] }, { "uniprot_ac": "A0A8V0XMX8", "gene_name": "MASTL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XMX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMX8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XMX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMX8" } ] } ] }, { "uniprot_ac": "A0A8V0XND6", "gene_name": "RIOK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XND6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XND6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XND6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XND6" } ] } ] }, { "uniprot_ac": "A0A8V0XNJ2", "gene_name": "CDK8", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XNJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNJ2" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XNJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNJ2" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0XNJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNJ2" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A8V0XNJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNJ2" } ] } ] }, { "uniprot_ac": "A0A8V0XNK8", "gene_name": "PRKCQ", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XNK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNK8" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V0XNK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNK8" } ] } ] }, { "uniprot_ac": "A0A8V0XQ14", "gene_name": "PLK4", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XQ14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ14" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0A8V0XQ14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ14" } ] } ] }, { "uniprot_ac": "A0A8V0XQ97", "gene_name": "CDK14", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XQ97", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ97" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0XQ97", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ97" } ] } ] }, { "uniprot_ac": "A0A8V0XQQ4", "gene_name": "NME7", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP 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"id": "A0A8V0XXB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XXB8" } ] } ] }, { "uniprot_ac": "A0A8V0Y074", "gene_name": "NEK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y074", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y074" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y074", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y074" } ] } ] }, { "uniprot_ac": "A0A8V0Y241", "gene_name": "LOC426385", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y241", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y241" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y241", "database": "UniProtKB", "url": 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"L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] } ] }, { "uniprot_ac": "A0A8V0Y3D1", "gene_name": "LRRK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y3D1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y3D1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y3D1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y3D1" } ] } ] }, { "uniprot_ac": "A0A8V0Y3L2", "gene_name": "MLK4", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + 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"UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y4L8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y4L8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y4L8" } ] } ] }, { "uniprot_ac": "A0A8V0Y6K1", "gene_name": "MAK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y6K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y6K1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y6K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y6K1" } ] } ] }, { "uniprot_ac": "A0A8V0Y7C3", "gene_name": "DAPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y7C3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y7C3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y7C3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y7C3" } ] } ] }, { "uniprot_ac": "A0A8V0Y823", "gene_name": "SRPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y823", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y823" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y823", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y823" } ] } ] }, { "uniprot_ac": "A0A8V0Y8X9", "gene_name": "PRKACA", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y8X9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y8X9" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "A0A8V0Y8X9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y8X9" } ] } ] }, { "uniprot_ac": "A0A8V0Y935", "gene_name": "MAST4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y935", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y935" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y935", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y935" } ] } ] }, { "uniprot_ac": "A0A8V0Y955", "gene_name": "PAK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y955", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y955" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y955", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y955" } ] } ] }, { "uniprot_ac": "A0A8V0Y9Q1", "gene_name": "LOC107055388", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y9Q1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9Q1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y9Q1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9Q1" } ] } ] }, { "uniprot_ac": "A0A8V0YCV9", "gene_name": "SIK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YCV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCV9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YCV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCV9" } ] } ] }, { 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"ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YDH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDH4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YDH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDH4" } ] } ] }, { "uniprot_ac": "A0A8V0YF83", "gene_name": "WNK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YF83", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF83" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YF83", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF83" } ] } ] }, { "uniprot_ac": "A0A8V0YFH4", "gene_name": "NRK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YFH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFH4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YFH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFH4" } ] } ] }, { "uniprot_ac": "A0A8V0YFL1", "gene_name": "CDK19", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YFL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFL1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0YFL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFL1" } ] } ] }, { "uniprot_ac": "A0A8V0YFP8", "gene_name": "RIPK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YFP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFP8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YFP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFP8" } ] } ] }, { "uniprot_ac": "A0A8V0YFR6", "gene_name": "TNIK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YFR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFR6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YFR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFR6" } ] } ] }, { "uniprot_ac": "A0A8V0YGW2", "gene_name": "STK32B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YGW2", "database": "UniProtKB", "url": 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"ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YHN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHN2" } ] } ] }, { "uniprot_ac": "A0A8V0YIV6", "gene_name": "DYRK1A", "activity": [ { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] }, { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] } ] }, { "uniprot_ac": "A0A8V0YJP9", "gene_name": "RIOK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YJP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJP9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YJP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJP9" } ] } ] }, { "uniprot_ac": "A0A8V0YK18", "gene_name": "CDC42BPB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YK18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK18" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YK18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK18" } ] } ] }, { "uniprot_ac": "A0A8V0YKK3", "gene_name": "MAP4K4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YKK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKK3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YKK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKK3" } ] } ] }, { "uniprot_ac": "A0A8V0YLV1", "gene_name": "MARK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YLV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLV1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YLV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLV1" } ] } ] }, { "uniprot_ac": "A0A8V0YM22", "gene_name": "MYO3AL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YM22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM22" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YM22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM22" } ] } ] }, { "uniprot_ac": "A0A8V0YM96", "gene_name": "STK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YM96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM96" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YM96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM96" } ] } ] }, { "uniprot_ac": "A0A8V0YMB3", "gene_name": "STK32A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YMB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMB3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YMB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMB3" } ] } ] }, { "uniprot_ac": "A0A8V0YMN5", "gene_name": "BRAF", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YMN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMN5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YMN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMN5" } ] } ] }, { "uniprot_ac": "A0A8V0YNI5", "gene_name": "NIM1K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YNI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNI5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YNI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNI5" } ] } ] }, { "uniprot_ac": "A0A8V0YRC9", "gene_name": "TNK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YRC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRC9" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YRC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRC9" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0YRC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRC9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YRC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRC9" } ] } ] }, { "uniprot_ac": "A0A8V0YRN4", "gene_name": "GAK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YRN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRN4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YRN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRN4" } ] } ] }, { "uniprot_ac": "A0A8V0YSH3", "gene_name": "RPS6KA6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YSH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSH3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YSH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSH3" } ] } ] }, { "uniprot_ac": "A0A8V0YTI1", "gene_name": "TSSK6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTI1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTI1" } ] } ] }, { "uniprot_ac": "A0A8V0YTL9", "gene_name": "VRK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTL9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTL9" } ] } ] }, { "uniprot_ac": "A0A8V0YTN5", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTN5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTN5" } ] } ] }, { "uniprot_ac": "A0A8V0YTP2", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTP2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTP2" } ] } ] }, { "uniprot_ac": "A0A8V0YXZ5", "gene_name": "CDC42BPA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YXZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXZ5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YXZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXZ5" } ] } ] }, { "uniprot_ac": "A0A8V0YYX2", "gene_name": "PAK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YYX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYX2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YYX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYX2" } ] } ] }, { "uniprot_ac": "A0A8V0YYZ3", "gene_name": "SPEG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YYZ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYZ3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YYZ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYZ3" } ] } ] }, { "uniprot_ac": "A0A8V0YZ74", "gene_name": "MAP2K5", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZ74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZ74" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V0YZ74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZ74" } ] } ] }, { "uniprot_ac": "A0A8V0YZF2", "gene_name": "PAK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZF2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YZF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZF2" } ] } ] }, { "uniprot_ac": "A0A8V0YZK0", "gene_name": "MAP3K6", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZK0" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0YZK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZK0" } ] } ] }, { "uniprot_ac": "A0A8V0YZM1", "gene_name": "MOK", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZM1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0YZM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZM1" } ] }, { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZM1" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0YZM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZM1" } ] } ] }, { "uniprot_ac": "A0A8V0YZV9", "gene_name": "ATR", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZV9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YZV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZV9" } ] } ] }, { "uniprot_ac": "A0A8V0YZY4", "gene_name": "SBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZY4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YZY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZY4" } ] } ] }, { "uniprot_ac": "A0A8V0Z124", "gene_name": "VRK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z124", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z124" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z124", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z124" } ] } ] }, { "uniprot_ac": "A0A8V0Z157", "gene_name": "MARK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z157", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z157" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z157", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z157" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A8V0Z157", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z157" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z157", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z157" } ] } ] }, { "uniprot_ac": "A0A8V0Z1X0", "gene_name": "MAP4K3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z1X0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1X0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z1X0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1X0" } ] } ] }, { "uniprot_ac": "A0A8V0Z283", "gene_name": "MARK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z283", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z283" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z283", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z283" } ] }, { "ec_number": "2.7.11.26", 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O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZKA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKA2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZKA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKA2" } ] } ] }, { "uniprot_ac": "A0A8V0ZKM9", "gene_name": "STK36", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZKM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKM9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZKM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKM9" } ] } ] }, { "uniprot_ac": "A0A8V0ZLU3", "gene_name": "TLK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": 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"ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZPX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPX2" } ] } ] }, { "uniprot_ac": "A0A8V0ZQJ2", "gene_name": "RPS6KB2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZQJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQJ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZQJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQJ2" } ] } ] }, { "uniprot_ac": "A0A8V0ZQT5", "gene_name": "SLC13A3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZQT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQT5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": 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"database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSP4" } ] } ] }, { "uniprot_ac": "A0A8V0ZT63", "gene_name": "STK25", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZT63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT63" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZT63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT63" } ] } ] }, { "uniprot_ac": "A0A8V0ZUC6", "gene_name": "PAK6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZUC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUC6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZUC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUC6" } ] } ] }, { "uniprot_ac": "A0A8V0ZUL0", "gene_name": "PASK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZUL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUL0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZUL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUL0" } ] } ] }, { "uniprot_ac": "A0A8V0ZUU8", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZUU8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUU8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZUU8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUU8" } ] } ] }, { 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[ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZWW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWW1" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0ZWW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWW1" } ] } ] }, { "uniprot_ac": "A0A8V0ZXQ9", "gene_name": "PRKG1", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZXQ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXQ9" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "A0A8V0ZXQ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXQ9" } ] } ] }, { "uniprot_ac": "A0A8V0ZYU6", "gene_name": "TNNI3K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZYU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZYU6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZYU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZYU6" } ] } ] }, { "uniprot_ac": "A0A8V0ZZE4", "gene_name": "OBSCN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZZE4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZE4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZZE4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZE4" } ] } ] }, { "uniprot_ac": "A0A8V0ZZK5", "gene_name": "STK38", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZZK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZK5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZZK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZK5" } ] } ] }, { "uniprot_ac": "A0A8V0ZZV3", "gene_name": "MYO3B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZZV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZV3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZZV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZV3" } ] } ] }, { "uniprot_ac": "A0A8V1A069", "gene_name": "TESK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A069", "database": "UniProtKB", "url": 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"ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A0Y8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0Y8" } ] } ] }, { "uniprot_ac": "A0A8V1A1P3", "gene_name": "SRPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A1P3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1P3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A1P3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1P3" } ] } ] }, { "uniprot_ac": "A0A8V1A1Y7", "gene_name": "CDK2", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A1Y7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1Y7" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": 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"https://www.uniprot.org/uniprotkb/A0A8V1A3T8" } ] } ] }, { "uniprot_ac": "A0A8V1A4A1", "gene_name": "CAMKK2", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4A1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4A1" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V1A4A1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4A1" } ] } ] }, { "uniprot_ac": "A0A8V1A4J8", "gene_name": "MAPKAPK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4J8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4J8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A4J8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4J8" } ] } ] }, { "uniprot_ac": "A0A8V1A4Q4", "gene_name": "MAPK3", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4Q4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4Q4" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V1A4Q4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4Q4" } ] } ] }, { "uniprot_ac": "A0A8V1A4V7", "gene_name": "HIPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4V7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4V7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A4V7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4V7" } ] } ] }, { "uniprot_ac": "A0A8V1A513", "gene_name": "DAPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A513", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A513" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A513", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A513" } ] } ] }, { "uniprot_ac": "A0A8V1A675", "gene_name": "CSNK1G2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A675", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A675" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A675", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A675" } ] } ] }, { "uniprot_ac": "A0A8V1A7E0", "gene_name": "DYRK3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7E0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E0" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V1A7E0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E0" } ] } ] }, { "uniprot_ac": "A0A8V1A7E9", "gene_name": "SIK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7E9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A7E9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E9" } ] } ] }, { "uniprot_ac": "A0A8V1A7M0", "gene_name": "STK39", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7M0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7M0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A7M0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7M0" } ] } ] }, { "uniprot_ac": "A0A8V1A7P9", "gene_name": "DCAF1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A7P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P9" } ] } ] }, { "uniprot_ac": "A0A8V1A9S5", "gene_name": "NUAK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A9S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9S5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A9S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9S5" } ] } ] }, { "uniprot_ac": "A0A8V1ABF3", "gene_name": "PRKAA2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] } ] }, { "uniprot_ac": "A0A8V1ABP4", "gene_name": "DSTYK", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABP4" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V1ABP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABP4" } ] } ] }, { "uniprot_ac": "A0A8V1ABR8", "gene_name": "CAMK4L", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABR8" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V1ABR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABR8" } ] } ] }, { "uniprot_ac": "A0A8V1AC40", "gene_name": "CDK18", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AC40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC40" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V1AC40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC40" } ] } ] }, { "uniprot_ac": "A0A8V1ACB5", "gene_name": "MAPK13", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACB5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V1ACB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACB5" } ] } ] }, { "uniprot_ac": "A0A8V1ACF6", "gene_name": "PIM1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACF6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ACF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACF6" } ] } ] }, { "uniprot_ac": "A0A8V1ACK0", "gene_name": "MAPKAPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACK0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ACK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACK0" } ] } ] }, { "uniprot_ac": "A0A8V1ACW2", "gene_name": "WNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACW2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ACW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACW2" } ] } ] }, { "uniprot_ac": "A0A8V1ADF0", "gene_name": "MAP2K2", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ADF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADF0" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V1ADF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADF0" } ] } ] }, { "uniprot_ac": "A0A8V1ADN9", "gene_name": "NLK", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ADN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADN9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V1ADN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADN9" } ] } ] }, { "uniprot_ac": "A0A8V1ADT4", "gene_name": "MKNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ADT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADT4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ADT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADT4" } ] } ] }, { "uniprot_ac": "A0A8V1AE45", "gene_name": "ERN1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AE45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE45" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AE45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE45" } ] } ] }, { "uniprot_ac": "A0A8V1AEH4", "gene_name": "STK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AEH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEH4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AEH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEH4" } ] } ] }, { "uniprot_ac": "A0A8V1AFS4", "gene_name": "STKLD1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AFS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFS4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AFS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFS4" } ] } ] }, { "uniprot_ac": "A0A8V1AG70", "gene_name": "LOC100857512", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AG70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AG70" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AG70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AG70" } ] } ] }, { "uniprot_ac": "A0A8V1AH12", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AH12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH12" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AH12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH12" } ] } ] }, { "uniprot_ac": "A0A8V1AHA8", "gene_name": "NEK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AHA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHA8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AHA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHA8" } ] } ] }, { "uniprot_ac": "A0A8V1AIY7", "gene_name": "AATK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AIY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIY7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AIY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIY7" } ] } ] }, { "uniprot_ac": "A0A8V1AJA4", "gene_name": "RPS6KB1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AJA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJA4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AJA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJA4" } ] } ] }, { "uniprot_ac": "A0A8V1AKW4", "gene_name": "MAP2K4", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AKW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKW4" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V1AKW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKW4" } ] } ] }, { "uniprot_ac": "A0A8V1AM12", "gene_name": "GSG2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AM12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM12" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AM12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM12" } ] } ] }, { "uniprot_ac": "A0A8V1AMK5", "gene_name": "PRKCA", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AMK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMK5" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V1AMK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMK5" } ] } ] }, { "uniprot_ac": "A0A8V1AMQ2", "gene_name": "CAMKK1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AMQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMQ2" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V1AMQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMQ2" } ] } ] }, { "uniprot_ac": "A0A8V1AP60", "gene_name": "KSR1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AP60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP60" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AP60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP60" } ] } ] }, { "uniprot_ac": "E1BQN6", "gene_name": "PRKCZ", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BQN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQN6" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1BQN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQN6" } ] } ] }, { "uniprot_ac": "E1BQV7", "gene_name": "SLK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BQV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQV7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BQV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQV7" } ] } ] }, { "uniprot_ac": "E1BUG0", "gene_name": "CDK12", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] } ] }, { "uniprot_ac": "E1BW33", "gene_name": "SMG1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BW33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BW33" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BW33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BW33" } ] } ] }, { "uniprot_ac": "E1BWA3", "gene_name": "PRKCI", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BWA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWA3" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1BWA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWA3" } ] } ] }, { "uniprot_ac": "E1BWT0", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BWT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWT0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BWT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWT0" } ] } ] }, { "uniprot_ac": "E1BX69", "gene_name": "EIF2AK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BX69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BX69" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BX69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BX69" } ] } ] }, { "uniprot_ac": "E1BY69", "gene_name": "PIM3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BY69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BY69" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BY69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BY69" } ] } ] }, { "uniprot_ac": "E1BYH2", "gene_name": "TAOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BYH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BYH2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BYH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BYH2" } ] } ] }, { "uniprot_ac": "E1C093", "gene_name": "PIK3CG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.154", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.154", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] } ] }, { "uniprot_ac": "E1C2I2", "gene_name": "MASTL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C2I2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C2I2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C2I2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C2I2" } ] } ] }, { "uniprot_ac": "E1C581", "gene_name": "TBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C581", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C581" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C581", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C581" } ] } ] }, { "uniprot_ac": "E1C6T4", "gene_name": "PRKD3", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C6T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C6T4" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1C6T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C6T4" } ] } ] }, { "uniprot_ac": "E1C764", "gene_name": "BMP2K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C764", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C764" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C764", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C764" } ] } ] }, { "uniprot_ac": "E1C848", "gene_name": "MAP3K8", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C848", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C848" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1C848", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C848" } ] } ] }, { "uniprot_ac": "F1NA68", "gene_name": "CDK3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NA68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NA68" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1NA68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NA68" } ] } ] }, { "uniprot_ac": "F1NB57", "gene_name": "PLK2", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NB57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NB57" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "F1NB57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NB57" } ] } ] }, { "uniprot_ac": "F1NBT0", "gene_name": "STK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NBT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NBT0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1NBT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NBT0" } ] } ] }, { "uniprot_ac": "F1NCX7", "gene_name": "PLK1", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NCX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCX7" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "F1NCX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCX7" } ] } ] }, { "uniprot_ac": "F1NCY7", "gene_name": "MAPKAPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NCY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCY7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1NCY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCY7" } ] } ] }, { "uniprot_ac": "F1NJH1", "gene_name": "PRKCH", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NJH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NJH1" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1NJH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NJH1" } ] } ] }, { "uniprot_ac": "F1NKW3", "gene_name": "MAP3K15", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NKW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NKW3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1NKW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NKW3" } ] } ] }, { "uniprot_ac": "F1NLR7", "gene_name": "CLK3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NLR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NLR7" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "F1NLR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NLR7" } ] } ] }, { "uniprot_ac": "F1NUX4", "gene_name": "MTOR", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NUX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NUX4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1NUX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NUX4" } ] } ] }, { "uniprot_ac": "F1NVF2", "gene_name": "MAP2K6", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NVF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NVF2" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "F1NVF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NVF2" } ] } ] }, { "uniprot_ac": "F1P011", "gene_name": "CAMK2A", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1P011", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P011" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "F1P011", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P011" } ] } ] }, { "uniprot_ac": "F1P356", "gene_name": "NUAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1P356", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P356" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1P356", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P356" } ] } ] }, { "uniprot_ac": "F1P4G3", "gene_name": "HIPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1P4G3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P4G3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1P4G3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P4G3" } ] } ] }, { "uniprot_ac": "P05625", "gene_name": "RAF1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P05625", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05625" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P05625", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05625" } ] } ] }, { "uniprot_ac": "P10741", "gene_name": "MOS", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P10741", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P10741" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P10741", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P10741" } ] } ] }, { "uniprot_ac": "P13863", "gene_name": "CDK1", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P13863", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13863" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "P13863", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13863" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "P13863", "database": "UniProtKB", "url": 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"section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YDH5-1", "uniprot_ac": "A0A8V0YDH5", "uniprot_id": "A0A8V0YDH5_CHICK", "mass": { "chemical_mass": 44983.0, "monoisotopic_mass": 44983.0 }, "refseq": {}, "gene_names": [ { "name": "RIBC1", "type": "recommended", "evidence": [ { "id": "A0A8V0YDH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDH5" } ] } ], "protein_names": [ { "name": "RIB43A domain with coiled-coils 1", "type": "synonym", "evidence": [ { "id": "A0A8V0YDH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDH5/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YDH5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDH5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RIBC1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDH5", "locus": {} } ], "crossref": [ { "id": "A0A8V0YDH5", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YDH5", "database": "AlphaFoldDB", "categories": [] }, { "id": "418244", "url": "https://www.ncbi.nlm.nih.gov/gene/418244", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR008805", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008805", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:418244", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418244", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "NLCRAIN", "url": "https://omabrowser.org/oma/group/NLCRAIN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YDH5", "url": "https://www.orthodb.org/?gene=A0A8V0YDH5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YLK9", "url": "https://www.orthodb.org/?gene=A0A8V0YLK9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14517", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14517", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14517:SF10", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14517:SF10", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05914", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05914", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_416468", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_416468", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YDH5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDH5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YDH5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDH5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLK9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLK9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLK9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLK9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSGLRVQRDLQEAAALERRRQRELQRQGRIFNARVRTIGVDKDALDAQVKDRKIQEATEKARNEELANEMKQNDKMMCMLEEQQKRNIRNINKAVSDFQKNFQKPETRREFDLSDPQALKKDRPARLSDNDPRCTVSGLQKFMGEDLNYAQRTKFQKEQLREWSLQQQRDHKNALADKKFLDDLHDKNRIELDRKTMEQQRIEEETRRAVCAATKDFNKSQAAEVAERKKLDKRQKMKDDMDEISSLLQGNLLSENPAQAISSFGTHRVITDRWKGMSQDQLMAIRSFQQQQVLEKLRLKEEERHRDAEWDRQSMQAARAQLILERHQERQNRERRQALDSINAQLSHEQKSKNIYLKEEEYSNCPTSQYFAQFNTTSR", "length": 379, "header": "tr|A0A8V0YDH5-1|A0A8V0YDH5_CHICK Isoform 1 of RIB43A domain with coiled-coils 1 OS=Gallus gallus OX=9031 GN=RIBC1 PE=1 SV=1 CANONICAL=A0A8V0YDH5-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YDH5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDH5/entry#A0A8V0YDH5-1", "sequence": { "sequence": "MSGLRVQRDLQEAAALERRRQRELQRQGRIFNARVRTIGVDKDALDAQVKDRKIQEATEKARNEELANEMKQNDKMMCMLEEQQKRNIRNINKAVSDFQKNFQKPETRREFDLSDPQALKKDRPARLSDNDPRCTVSGLQKFMGEDLNYAQRTKFQKEQLREWSLQQQRDHKNALADKKFLDDLHDKNRIELDRKTMEQQRIEEETRRAVCAATKDFNKSQAAEVAERKKLDKRQKMKDDMDEISSLLQGNLLSENPAQAISSFGTHRVITDRWKGMSQDQLMAIRSFQQQQVLEKLRLKEEERHRDAEWDRQSMQAARAQLILERHQERQNRERRQALDSINAQLSHEQKSKNIYLKEEEYSNCPTSQYFAQFNTTSR", "length": 379, "header": "tr|A0A8V0YDH5-1|A0A8V0YDH5_CHICK Isoform 1 of RIB43A domain with coiled-coils 1 OS=Gallus gallus OX=9031 GN=RIBC1 PE=1 SV=1 CANONICAL=A0A8V0YDH5-1" }, "locus": { "chromosome": "1", "start_pos": 70495756, "end_pos": 70482174, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029275.1", "url": "https://www.ensembl.org/id/ENSGALT00010029275.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016992.1", "url": "https://www.ensembl.org/id/ENSGALP00010016992.1" } ] } }, { "isoform_ac": "A0A8V0YLK9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDH5/entry#A0A8V0YLK9-1", "sequence": { "sequence": "MKQNDKMMCMLEEQQKRNIRNINKAVSDFQKNFQKPETRREFDLSDPQALKKDRPARLSDNDPRCTVSGLQKFMGEDLNYAQRTKFQKEQLREWSLQQQRDHKNALADKKFLDDLHDKNRIELDRKTMEQQRIEEETRRAVCAATKDFNKSQAAEVAERKKLDKRQKMKDDMDEISSLLQGNLLSENPAQAISSFGTHRVITDRWKGMSQDQLMAIRSFQQQQVLEKLRLKEEERHRDAEWDRQSMQAARAQLILERHQERQNRERRQALDSINAQLSHEQKSKNIYLKEEEYSNCPTSQYFAQFNTTSR", "length": 310, "header": "tr|A0A8V0YLK9-1|A0A8V0YLK9_CHICK Computationally mapped isoform of RIB43A domain with coiled-coils 1 OS=Gallus gallus OX=9031 GN=RIBC1 PE=1 SV=1 CANONICAL=A0A8V0YDH5-1" }, "locus": { "chromosome": "1", "start_pos": 70495756, "end_pos": 70488201, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029266.1", "url": "https://www.ensembl.org/id/ENSGALT00010029266.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016984.1", "url": "https://www.ensembl.org/id/ENSGALP00010016984.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:418244", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418244", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3L7IAN2-1", "protein_name": "RIB43A-like with coiled-coils protein 2 isoform X2", "gene_name": "Ribc2", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MDVATLKDLQQDATLAKRQYMELCRQGQIFDARNRIIGGDPQAWDVQVREQKIKEATEKARQETFAAEMRHNDKIMCLLHDRERRDKKQLCCAINDFQQRFQKPETRREFDLSDPLALKKDLPARVSDSDPRNSISGMQKFIGEDLNFHWRKKFQQEQNREWYLQQYREWERARADHKLAEDLYTQTRLKFDEKARELQKLENFTRKELCAATKEFNKNQAMELAERKRQEKQQEQEDNMTEISNLLHSDLLTESSQQATSSFGPHQVVLYRWKGMSPEQLEEIRYTQKQQIQEKLRLQEEERQRNMDWDRRRIQKARANLLHERQQQRLHRELRKALDCSNLNLARKQYSQKKQMNIASTSQPTEDFFSQFNTRSR", "length": 377 }, "evidence": [ { "id": "A0A8V0YDH5", "url": "https://omabrowser.org/oma/group/A0A8V0YDH5/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "E7F099-1", "protein_name": "RIB43A-like with coiled-coils protein 2", "gene_name": "ribc2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MNQVEHLSDRVAAVHLDRRRIREQKRQERIFSDKVRTIGVDIDALGQQIKERREKEQREANELKVYADDLLCSDGIACILEQRQKKDERQLNKDIVQFRQQFQQASSRREFDLNDPELLKKQEGQRILPGLVGEDLGQKNRLRKQQEQLYSWTTQQKEEVERAKLQRKQEENQYDQIRMSLDSRALELQKMEEQTKRDLLIATKDFNLALAAEITHRRLQEHREEEENNQTEIYNQLNGDLLMENPEQNVSVLGLSRLRRDCYKGMSPQELQTYTQYQRQQAEDRKRANMEQRQKDLQEHQERMSSARAALLLERQQARINKELRRAMDNSNSQLAHIHDARKKHLQDVYTNIPDERYYSQFNTSSR", "length": 367 }, "evidence": [ { "id": "A0A8V0YDH5", "url": "https://omabrowser.org/oma/group/A0A8V0YDH5/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q32LJ7-1", "protein_name": "RIB43A-like with coiled-coils protein 2", "gene_name": "RIBC2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MEVAQPKDLKEDFVLAKRRHAELVRQKRIFNARNRIIGGDTTAWDAQVCDQNIKAATEKARDEAFAAEMRQNDKIACLSENRERRDRKNLCKAINDFQQSFQRPETRREFDLSDPLALKKDRPARQSDYDARNTISGMQKFMGEDLNFHLRKKFQEEQNREWSLQQQKEQMIGRENQKCAEDLYLKTRLQFDETAKHLQNLETATRKAVCATVKEFNKNQALESAEKKIQERKQEQEDNLAEISNMLRGDLLSENPQQAASSFGPHRVVPDRWKGMSQEQLEEIRLVQRQQVQEKLRLQEEERQRDMDWDRRRIQKARATLLFEQQQQRLQRGLRRALDCSNLSLAREQLLQKKHMKELCTNHATEDYFTQFNTGSR", "length": 377 }, "evidence": [ { "id": "A0A8V0YDH5", "url": "https://omabrowser.org/oma/group/A0A8V0YDH5/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q6AXN9-1", "protein_name": "RIB43A-like with coiled-coils protein 2", "gene_name": "Ribc2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEVAIPKDLQQEASLAKKRYMDLCRQGQIFDARNRIIGGDTQAWDVQVRNQKIKEVTEKARDETFAAEMRHNDKVMCIMHDRELRHRKQLCRAINDFQQRFQKPETRREFDLSDPLALKKELPARVSDNDMRNTISGMQKFMGEDLNFQERKRIQKEQNREWSLQQHGEWERAQAEHKLAEHLHTQTELKFDEAARDLQRLEITTRKAVCAAVKEFNKKQVVELAERKRQVKQQEQEDNMSEITNLLHGDLLSENPQQAASNFGPRHVMLDRWKGMNREQLEEIWSTWKQQIHEKLRLQEEERQHNMDWDLRRTRKAHASLLQERQQQRLLREQRRALDCSNLSLAKQQYLQKRQLDAAPSSQPTEDYFSQFNTRSR", "length": 377 }, "evidence": [ { "id": "A0A8V0YDH5", "url": "https://omabrowser.org/oma/group/A0A8V0YDH5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9D4Q1-1", "protein_name": "RIB43A-like with coiled-coils protein 2", "gene_name": "Ribc2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEVAMSKDLQQEANLAKKRYIDLCRQGRIFDARNRIIGGDTQAWDFQVRDQKIKEITDKARHEAFAAEMKHNDKVMCMAHDREQRHRKQLCRAINDFQQNFQKPETRREFDLSDPLALQKELPARISDNDMRNTISGMQKFMGEDLNFQERRRFQKEQSREWFLQQHGEREKARADHLLAEHLHTQTRLKFDETARELMKLEGSTRKEVCAAVKAFNKNQVVELTERKRQEKQQEQEDNMTEITNLLHGDLLSENPRPVASSFGSHRVVLDRWKGMNREQLEEIWFTQKRQIQEKLRLQEEERQHSMDWDLRRIRKAHASLLHERQQQRLLREQRRALDCSNLNLARQQYLQKKQMNTASSSQPTEDYFSQFNTRSR", "length": 377 }, "evidence": [ { "id": "A0A8V0YDH5", "url": "https://omabrowser.org/oma/group/A0A8V0YDH5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9H4K1-1", "protein_name": "RIB43A-like with coiled-coils protein 2", "gene_name": "RIBC2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGSQTMAVALPRDLRQDANLAKRRHAELCRQKRVFNARNRIIGGDTEAWDVQVHDQKIKEATEKARHETFAAEMRQNDKIMCILENRKKRDRKNLCRAINDFQQSFQKPETRREFDLSDPLALKKDLPARQSDNDVRNTISGMQKFMGEDLNFHERKKFQEEQNREWSLQQQREWKNARAEQKCAEALYTETRLQFDETAKHLQKLESTTRKAVCASVKDFNKSQAIESVERKKQEKKQEQEDNLAEITNLLRGDLLSENPQQAASSFGPHRVVPDRWKGMTQEQLEQIRLVQKQQIQEKLRLQEEKRQRDLDWDRRRIQGARATLLFERQQWRRQRDLRRALDSSNLSLAKEQHLQKKYMNEVYTNQPTGDYFTQFNTGSR", "length": 382 }, "evidence": [ { "id": "A0A8V0YDH5", "url": "https://omabrowser.org/oma/group/A0A8V0YDH5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VTP5-1", "protein_name": "RIB43A-like with coiled-coils protein 2", "gene_name": "Dmel\\CG7264", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MTLKIGICTKQDLDEAMKLQKREQYEDERKRRIFNAKQRLYGLDLEMLDRQILEKKKQRTAQMECDKKFEEQEQLQKRLILAQEMELEKKQRVVDSDLNYYRCRYQRKEQRREFDLNDPNFLKKARPTRVADNDISLGVSSAQIFQGEDLYNSDRKQRQREQQRAWLDQQVQERKRAEDARKQADNVLMDNVGCRDKHLQEMAKSDHQMRNQVIQRVRQFNINMAKQKQLDREREKREKYEDDMAEIYNMLSSDMLTENPDVAQSRTDPNKKIAFMYRGMTPEELRVFRLGQDQQLRLSIQRKTEAQMMDKQWEQYSINMDRTLVLHQIEDDRRRKAEFDELMRANSKLAVEQDRQRKEALVGLTNAVSDDFYDQFNKNSR", "length": 381 }, "evidence": [ { "id": "A0A8V0YDH5", "url": "https://omabrowser.org/oma/group/A0A8V0YDH5/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "flagellated sperm motility", "id": "GO:0030317", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030317", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YDH5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDH5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "sperm flagellum", "id": "GO:0036126", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036126", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YDH5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDH5" } ], "pmid": "" }, { "name": "axonemal A tubule inner sheath", "id": "GO:0160111", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160111", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YDH5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDH5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 218, "end_pos": 220, "annotation": "n_glycosylation_sequon" }, { "start_pos": 375, "end_pos": 377, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", 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{ "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YDJ2-1", "uniprot_ac": "A0A8V0YDJ2", "uniprot_id": "A0A8V0YDJ2_CHICK", "mass": { "chemical_mass": 24034.0, "monoisotopic_mass": 24034.0 }, "refseq": { "ac": "XP_040523870", "name": "transmembrane protein 140", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040523870" }, "gene_names": [ { "name": "TMEM140", "type": "recommended", "evidence": [ { "id": "A0A8V0YDJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDJ2" } ] }, { "name": "TMEM140", "type": "synonym", "evidence": [ { "id": "XP_040523870", "database": "RefSeq", 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This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. 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"MAVIASGPTAGFTMVSRKHVGHGTALLRWRYMGHLLCALTILEVAATLGLMIYALLVEAGNLVDLSNKRIGFYNFCLWNETAGKLQCLEVRHLQAMGISWLGIALARVCVYMCPVISFFYPLFLANMRCKDKVEGWRVLLIILITKMLLLSGGLGIFLLQTSPWINLSDFTGGFLALVGILALILLQILTIITHAIWAKHINPHQSPFTEEALPIKI", "length": 217, "header": "tr|A0A8V0YDJ2-1|A0A8V0YDJ2_CHICK Isoform 1 of Transmembrane protein 140 OS=Gallus gallus OX=9031 GN=TMEM140 PE=4 SV=1 CANONICAL=A0A8V0YDJ2-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Y7C7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDJ2/entry#A0A8V0Y7C7-1", "sequence": { "sequence": "MVSRKHVGHGTALLRWRYMGHLLCALTILEVAATLGLMIYALLVEAGNLVDLSNKRIGFYNFCLWNETAGKLQCLEVRHLQAMGISWLGIALARVCVYMCPVISFFYPLFLANMRCKDKVEGWRVLLIILITKMLLLSGGLGIFLLQTSPWINLSDFTGGFLALVGILALILLQILTIITHAIWAKHINPHQSPFTEEALPIKI", "length": 204, "header": "tr|A0A8V0Y7C7-1|A0A8V0Y7C7_CHICK Computationally mapped isoform of Transmembrane protein 140 OS=Gallus gallus OX=9031 GN=TMEM140 PE=4 SV=1 CANONICAL=A0A8V0YDJ2-1" }, "locus": { "chromosome": "1", "start_pos": 47965498, 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] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052544.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015149078", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015149078" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YDJ9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDJ9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "FBXW11", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDJ9", "locus": { "chromosome": "13", "start_pos": 2528077, "end_pos": 2462888, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010010347", "url": "https://www.ensembl.org/id/ENSGALG00010010347" } ] } } ], "crossref": [ { "id": "A0A8V0YDJ9", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YDJ9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000002229", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000002229", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00200", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00200", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd22183", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22183", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "416181", "url": "https://www.ncbi.nlm.nih.gov/gene/416181", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001680", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001680", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001810", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001810", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019775", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019775", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020472", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020472", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR021977", "url": "https://www.ebi.ac.uk/interpro/entry/IPR021977", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036047", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036047", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036322", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036322", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050995", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050995", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHTACY", "url": "https://omabrowser.org/oma/group/PTHTACY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5NYD3", "url": "https://www.orthodb.org/?gene=A0A1D5NYD3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y6M1", "url": "https://www.orthodb.org/?gene=A0A8V0Y6M1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YDJ4", "url": "https://www.orthodb.org/?gene=A0A8V0YDJ4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YDJ9", "url": "https://www.orthodb.org/?gene=A0A8V0YDJ9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14604", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14604", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14604:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14604:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00400", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00400", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12125", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12125", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12937", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12937", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-69601", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-69601", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-8951664", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8951664", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-983168", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983168", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_015149078", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015149078", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5NYD3", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYD3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5NYD3-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYD3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y6M1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y6M1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y6M1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y6M1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YDJ4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDJ4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YDJ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDJ4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YDJ9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDJ9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YDJ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDJ9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEPDSVIEDKTIELMCSVPRSLWLGCSNLVESMCALRCLQSMPSVRCLQNTSVMEDQNEDESPKKNTLWQISNGTSSVIVSRKRPSEGNYEKEKDLCIKYFDQWSESDQVEFVEHLISRMCHYQHGHINSYLKPMLQRDFITALPEQGLDHIAENILSYLDARSLCAAELVCKEWQRVISEGMLWKKLIERMVRTDPLWKGLSERRSWDQYLFKNRPTDGPPNSFYRSLYPKIIQDIETIESNWRCGRHNLQRIQCRSENSKGVYCLQYDDEKIISGLRDNSIKIWDKTSLECLKVLTGHTGSVLCLQYDERVIVTGSSDSTVRVWDVNTGEVLNTLIHHNEAVLHLRFSNGLMVTCSKDRSIAVWDMASPTDITLRRVLVGHRAAVNVVDFDDKYIVSASGDRTIKVWSTSTCEFVRTLNGHKRGIACLQYRDRLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRFDNKRIVSGAYDGKIKVWDLQAALDPRAPASTLCLRTLVEHSGRVFRLQFDEFQIISSSHDDTILIWDFLNVPPSAPNETRSPSRTYTYISR", "length": 563, "header": "tr|A0A8V0YDJ9-1|A0A8V0YDJ9_CHICK Isoform 1 of F-box and WD repeat domain containing 11 OS=Gallus gallus OX=9031 GN=FBXW11 PE=4 SV=1 CANONICAL=A0A8V0YDJ9-1" }, "isoforms": [ { "isoform_ac": "A0A1D5NYD3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDJ9/entry#A0A1D5NYD3-1", "sequence": { "sequence": "MEDQNEDESPKKNTLWQISNGTSSVIVSRKRPSEGNYEKEKDLCIKYFDQWSESDQVEFVEHLISRMCHYQHGHINSYLKPMLQRDFITALPEQGLDHIAENILSYLDARSLCAAELVCKEWQRVISEGMLWKKLIERMVRTDPLWKGLSERRSWDQYLFKNRPTDGPPNSFYRSLYPKIIQDIETIESNWRCGRHNLQRIQCRSENSKGVYCLQYDDEKIISGLRDNSIKIWDKTSLECLKVLTGHTGSVLCLQYDERVIVTGSSDSTVRVWDVNTGEVLNTLIHHNEAVLHLRFSNGLMVTCSKDRSIAVWDMASPTDITLRRVLVGHRAAVNVVDFDDKYIVSASGDRTIKVWSTSTCEFVRTLNGHKRGIACLQYRDRLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRFDNKRIVSGAYDGKIKVWDLQAALDPRAPASTLCLRTLVEHSGRVFRLQFDEFQIISSSHDDTILIWDFLNVPPSAPNETRSPSRTYTYISR", "length": 510, "header": "tr|A0A1D5NYD3-1|A0A1D5NYD3_CHICK Computationally mapped isoform of F-box and WD repeat domain containing 11 OS=Gallus gallus OX=9031 GN=FBXW11 PE=4 SV=1 CANONICAL=A0A8V0YDJ9-1" }, "locus": { "chromosome": "13", "start_pos": 2522233, "end_pos": 2495591, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010024748.1", "url": "https://www.ensembl.org/id/ENSGALT00010024748.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010014034.1", "url": "https://www.ensembl.org/id/ENSGALP00010014034.1" } ] } }, { "isoform_ac": "A0A8V0Y6M1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDJ9/entry#A0A8V0Y6M1-1", "sequence": { "sequence": "MRAGCVRDSYTRSILGTIPAVPVENTSVMEDQNEDESPKKNTLWQISNGTSSVIVSRKRPSEGNYEKEKDLCIKYFDQWSESDQVEFVEHLISRMCHYQHGHINSYLKPMLQRDFITALPEQGLDHIAENILSYLDARSLCAAELVCKEWQRVISEGMLWKKLIERMVRTDPLWKGLSERRSWDQYLFKNRPTDGPPNSFYRSLYPKIIQDIETIESNWRCGRHNLQRIQCRSENSKGVYCLQYDDEKIISGLRDNSIKIWDKTSLECLKVLTGHTGSVLCLQYDERVIVTGSSDSTVRVWDVNTGEVLNTLIHHNEAVLHLRFSNGLMVTCSKDRSIAVWDMASPTDITLRRVLVGHRAAVNVVDFDDKYIVSASGDRTIKVWSTSTCEFVRTLNGHKRGIACLQYRDRLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRFDNKRIVSGAYDGKIKVWDLQAALDPRAPASTLCLRTLVEHSGRVFRLQFDEFQIISSSHDDTILIWDFLNVPPSAPNETRSPSRTYTYISR", "length": 538, "header": "tr|A0A8V0Y6M1-1|A0A8V0Y6M1_CHICK Computationally mapped isoform of F-box and WD repeat domain containing 11 OS=Gallus gallus OX=9031 GN=FBXW11 PE=4 SV=1 CANONICAL=A0A8V0YDJ9-1" }, "locus": { "chromosome": "13", "start_pos": 2522233, "end_pos": 2488266, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010024746.1", "url": "https://www.ensembl.org/id/ENSGALT00010024746.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010014033.1", "url": "https://www.ensembl.org/id/ENSGALP00010014033.1" } ] } }, { "isoform_ac": "A0A8V0YDJ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDJ9/entry#A0A8V0YDJ4-1", "sequence": { "sequence": "MPEFSCYQNTSVMEDQNEDESPKKNTLWQISNGTSSVIVSRKRPSEGNYEKEKDLCIKYFDQWSESDQVEFVEHLISRMCHYQHGHINSYLKPMLQRDFITALPEQGLDHIAENILSYLDARSLCAAELVCKEWQRVISEGMLWKKLIERMVRTDPLWKGLSERRSWDQYLFKNRPTDGPPNSFYRSLYPKIIQDIETIESNWRCGRHNLQRIQCRSENSKGVYCLQYDDEKIISGLRDNSIKIWDKTSLECLKVLTGHTGSVLCLQYDERVIVTGSSDSTVRVWDVNTGEVLNTLIHHNEAVLHLRFSNGLMVTCSKDRSIAVWDMASPTDITLRRVLVGHRAAVNVVDFDDKYIVSASGDRTIKVWSTSTCEFVRTLNGHKRGIACLQYRDRLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRFDNKRIVSGAYDGKIKVWDLQAALDPRAPASTLCLRTLVEHSGRVFRLQFDEFQIISSSHDDTILIWDFLNVPPSAPNETRSPSRTYTYISR", "length": 522, "header": "tr|A0A8V0YDJ4-1|A0A8V0YDJ9_CHICK Computationally mapped isoform of F-box and WD repeat domain containing 11 OS=Gallus gallus OX=9031 GN=FBXW11 PE=4 SV=1 CANONICAL=A0A8V0YDJ9-1" }, "locus": { "chromosome": "13", "start_pos": 2522233, "end_pos": 2491681, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010024745.1", "url": "https://www.ensembl.org/id/ENSGALT00010024745.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010014032.1", "url": "https://www.ensembl.org/id/ENSGALP00010014032.1" } ] } }, { "isoform_ac": "A0A8V0YDJ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDJ9/entry#A0A8V0YDJ9-1", "sequence": { "sequence": "MEPDSVIEDKTIELMCSVPRSLWLGCSNLVESMCALRCLQSMPSVRCLQNTSVMEDQNEDESPKKNTLWQISNGTSSVIVSRKRPSEGNYEKEKDLCIKYFDQWSESDQVEFVEHLISRMCHYQHGHINSYLKPMLQRDFITALPEQGLDHIAENILSYLDARSLCAAELVCKEWQRVISEGMLWKKLIERMVRTDPLWKGLSERRSWDQYLFKNRPTDGPPNSFYRSLYPKIIQDIETIESNWRCGRHNLQRIQCRSENSKGVYCLQYDDEKIISGLRDNSIKIWDKTSLECLKVLTGHTGSVLCLQYDERVIVTGSSDSTVRVWDVNTGEVLNTLIHHNEAVLHLRFSNGLMVTCSKDRSIAVWDMASPTDITLRRVLVGHRAAVNVVDFDDKYIVSASGDRTIKVWSTSTCEFVRTLNGHKRGIACLQYRDRLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRFDNKRIVSGAYDGKIKVWDLQAALDPRAPASTLCLRTLVEHSGRVFRLQFDEFQIISSSHDDTILIWDFLNVPPSAPNETRSPSRTYTYISR", "length": 563, "header": "tr|A0A8V0YDJ9-1|A0A8V0YDJ9_CHICK Isoform 1 of F-box and WD repeat domain containing 11 OS=Gallus gallus OX=9031 GN=FBXW11 PE=4 SV=1 CANONICAL=A0A8V0YDJ9-1" }, "locus": { "chromosome": "13", "start_pos": 2522233, "end_pos": 2462949, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010024753.1", "url": "https://www.ensembl.org/id/ENSGALT00010024753.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010014037.1", "url": "https://www.ensembl.org/id/ENSGALP00010014037.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-69601", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-69601", "resource": "Reactome", "description": "Ubiquitin-Mediated Degradation of Phosphorylated Cdc25A" }, { "id": "R-GGA-8951664", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8951664", "resource": "Reactome", "description": "Neddylation" }, { "id": "R-GGA-983168", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983168", "resource": "Reactome", "description": "Antigen processing: Ubiquitination & Proteasome degradation" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A2R8RWN9-1", "protein_name": "F-box and WD repeat domain-containing 11-B", "gene_name": "fbxw11b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MFDLKQTLLLISELMHLFLLRLQNTSVMDPQTADRSPKITLIKVSNGPLTGSRKRPSEGNYEKEKDVCIQLFDQWSEADQVEFVEHLISRMCHYQHGHINSYLKPMLQRDFITALPAQGLDHIAENILSFLDARSLCSAELVCKEWQRVISEGMLWKKLIERMVRTDPLWKGLSERHQWEKYLFKNRTTEVPPNSYYRSLYPKIIQDIETIEANWRCGRHNLQRIQCRSENSKGVYCLQYDDEKIISGLRDNSIKIWDKQTLECLKILTGHTGSVLCLQYDERVIVTGSSDSTVRVWDVNSGEVLNTLIHHNEAVLHLRFCNGLMVTCSKDRSIAVWDMASPTDISLRRVLVGHRAAVNVVDFDDKYIVSASGDRTIKVWSTSTCEFVRTLNGHKRGIACLQYRDRLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRFDNKRIVSGAYDGKIKVWDLQAALDPRAPASTLCLRTLVEHSGRVFRLQFDEFQIISSSHDDTILIWDFLNVSTNGQTEGRSPSRTYTYISR", "length": 534 }, "evidence": [ { "id": "A0A8V0YDJ9", "url": "https://omabrowser.org/oma/group/A0A8V0YDJ9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8I6GIW9-1", "protein_name": "F-box and WD repeat domain containing 11", "gene_name": "Fbxw11", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEPDSVIEDKTIELMCSVPRSLWLGCANLVESMCALSCLQSMPSVRCLQNTSVMEDQNEDESPKKSALWQVGMISNGTSSVIVSRKRPSEGNYQKEKDLCIKYFDQWSESDQVEFVEHLISRMCHYQHGHINSYLKPMLQRDFITALPEQGLDHIAENILSYLDARSLCAAELVCKEWQRVISEGMLWKKLIERMVRTDPLWKGLSERRGWDQYLFKNRPTDGPPNSFYRSLYPKIIQDIETIESNWRCGRHNLQRIQCRSENSKGVYCLQYDDDKIISGLRDNSIKIWDKSSLECLKVLTGHTGSVLCLQYDERVIVTGSSDSTVRVWDVNTGEVLNTLIHHNEAVLHLRFSNGLMVTCSKDRSIAVWDMASATDITLRRVLVGHRAAVNVVDFDDKYIVSASGDRTIKVWSTSTCEFVRTLNGHKRGIACLQYRDRLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRFDNKRIVSGAYDGKIKVWDLQAALDPRAPASTLCLRTLVEHSGRVFRLQFDEFQIISSSHDDTILIWDFLNVPPSAQNETRSPSRTYTYISR", "length": 566 }, "evidence": [ { "id": "A0A8V0YDJ9", "url": "https://omabrowser.org/oma/group/A0A8V0YDJ9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q54CP0-1", "protein_name": "WD40 repeat-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MLGPDFQKYSNQSNYHFDSFPYENSYEEEEYQDKYKEIVFRDKWGPKYAIQQQQQQQVYAPNKRNVSKKIGSPLSSPTLYSSSSSSSSSSSNCKNNNNQNINHYQHKKKDSKKLKEIIKNLLLPNKFNPMKRITFISILPIEITMKIISYLPFQDVLSIQYVCSEWFLITCEEILWKSIYQNYFQVYPNRELLLKKSEKSCQLHWREIFKQQHERESRWKGDRFKEAHLIGHTGTVWALHLDDERVYTGSFDKTAKVWDTKTKKCRFTLAGHYYPIQCLDVNNNIMATGSLDNSIRIWDLEKGKSKGILTTRAHNFDVFCLQQIGDQIISGSSDSTVKVWNIAEIINDSIEIPDTEEEEEEALQDNVMNDPFAVNNSFTSLPDINEPDHVHTNIVSVNDKTSTRYRNHNLSSTHTFKHQSCVTCLQVYGNILMSGGSDRVVRVWDLNTSQPIQILSGHNEGIRALQFNGNVLVTGSDDTTVRVWDLRSKNSNISTLRGHNGSVRCLQWDGTTLITGSNDQSVRWWNLNYDSDQSKELFSFNSSISCLQFTNSILMCGLSDSKVQINKFY", "length": 569 }, "evidence": [ { "id": "A0A8V0YDJ9", "url": "https://omabrowser.org/oma/group/A0A8V0YDJ9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q5SRY7-1", "protein_name": "F-box/WD repeat-containing protein 11", "gene_name": "Fbxw11", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEPDSVIEDKTIELMCSVPRSLWLGCANLVESMCALSCLQSMPSVRCLQISNGTSSVIVSRKRPSEGNYQKEKDLCIKYFDQWSESDQVEFVEHLISRMCHYQHGHINSYLKPMLQRDFITALPEQGLDHIAENILSYLDARSLCAAELVCKEWQRVISEGMLWKKLIERMVRTDPLWKGLSERRGWDQYLFKNRPTDGPPNSFYRSLYPKIIQDIETIESNWRCGRHNLQRIQCRSENSKGVYCLQYDDDKIISGLRDNSIKIWDKSSLECLKVLTGHTGSVLCLQYDERVIVTGSSDSTVRVWDVNTGEVLNTLIHHNEAVLHLRFSNGLMVTCSKDRSIAVWDMASATDITLRRVLVGHRAAVNVVDFDDKYIVSASGDRTIKVWSTSTCEFVRTLNGHKRGIACLQYRDRLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRFDNKRIVSGAYDGKIKVWDLQAALDPRAPASTLCLRTLVEHSGRVFRLQFDEFQIISSSHDDTILIWDFLNVPPSAQNETRSPSRTYTYISR", "length": 542 }, "evidence": [ { "id": "A0A8V0YDJ9", "url": "https://omabrowser.org/oma/group/A0A8V0YDJ9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9UKB1-1", "protein_name": "F-box/WD repeat-containing protein 11", "gene_name": "FBXW11", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEPDSVIEDKTIELMCSVPRSLWLGCANLVESMCALSCLQSMPSVRCLQISNGTSSVIVSRKRPSEGNYQKEKDLCIKYFDQWSESDQVEFVEHLISRMCHYQHGHINSYLKPMLQRDFITALPEQGLDHIAENILSYLDARSLCAAELVCKEWQRVISEGMLWKKLIERMVRTDPLWKGLSERRGWDQYLFKNRPTDGPPNSFYRSLYPKIIQDIETIESNWRCGRHNLQRIQCRSENSKGVYCLQYDDEKIISGLRDNSIKIWDKTSLECLKVLTGHTGSVLCLQYDERVIVTGSSDSTVRVWDVNTGEVLNTLIHHNEAVLHLRFSNGLMVTCSKDRSIAVWDMASATDITLRRVLVGHRAAVNVVDFDDKYIVSASGDRTIKVWSTSTCEFVRTLNGHKRGIACLQYRDRLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRFDNKRIVSGAYDGKIKVWDLQAALDPRAPASTLCLRTLVEHSGRVFRLQFDEFQIISSSHDDTILIWDFLNVPPSAQNETRSPSRTYTYISR", "length": 542 }, "evidence": [ { "id": "A0A8V0YDJ9", "url": "https://omabrowser.org/oma/group/A0A8V0YDJ9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "protein dimerization activity", "id": "GO:0046983", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046983", "evidence": [ { "database": "UniProtKB", "id": 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"https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13912", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13912", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0Y0G1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y0G1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y0G1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y0G1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y6N2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y6N2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y6N2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y6N2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y6P5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y6P5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y6P5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y6P5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y6Q0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y6Q0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y6Q0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y6Q0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y8X7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y8X7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y8X7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y8X7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y8Y2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y8Y2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y8Y2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y8Y2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y8Y7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y8Y7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y8Y7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y8Y7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YDK8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDK8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YDK8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDK8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YDL4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDL4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YDL4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDL4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MYCAAKATLWRRSAGSAGACVPFPLSCRLSPRLQVLEGATEEEAEEPDATKPTTLSEETSKQEESLSQSGDSNEEKQLETLNSYKVTPSSPNSSDGADLSSIDAMMSAVMNVGKIAENGGTSQTVKSPSKSPAPNRIGRRNQETKEEKSSYTCPLCEKICTTQHQLTMHIRQHNTDTGGTDHSCSICGKSLSSASSLDRHMLVHSGERPYKCSVCGQSFTTNGNMHRHMKIHEKDPNSTASTTPPSPLKRKRLSSKRKFSQDAEMDREERTPAKKVVEDGQYGEGDRKEDDAYHCPVCFKDFFCKYALESHMETHPDNSLRCDICCITFRTHRGLLRHNAVIHKQLPRDPTGKPFIQNNPSIPAGFHDLGFTDFSCRKFPRISQVWCETNLRRCISEFHRFICETCNKAFPMLLALKLHTETHVMDQGRDKHKLQSTSLPSENPDQKAFMASLGLQYTKDIKPVKQEDDTQDEVQEMRLRALKSNLPQEPGSTGLLSLSPLEAATMGGPFSVLPPTKENIKLLSLQPFQKGFIIQPDSSIVVKPISNESAIELADIQQILKMASSAPPQISLPPLSKAPSVPVQSIFKHMPPLKPKPLVTPRTVVATSTPPPLISAQQASPGCISPSLPPPPLRLIKNSVETSSNSHLSQPGAKSSPSSQLLLQPKVEPLTQHEMKTQLEQDSIIEALLPLNMEAKIKQEVTEGDLKAIIAGAANKKAPTMRKVLYPCRFCDQVFAFSGVLRAHIRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERPYICKICHYPFTVKANCERHLRKKHLKVTRKDIEKNIEYVTSNAAEMVDAFCSPDTVCKLCGEDLKHYRALRIHMRTHSGCQKKKPFECKECGTAFSAKRNCIHHILKQHLHVQEREIENYILVVDCSAQESHTDAPLLEDSTYMDCKPITPFLEPQNGFLLGTSSHVPIKLEPMGNFPMDFDEPLDFSQKSKNLSAVQVKQENLLVSSPLSFYDCSMEPIDLSIPKVLKRDNDIPGEARNQELASSVITDNAYNCQQCPLGFGANGNSEKNRAVGHPQPLKGSLHLTVPIISPALLGNSALLRPLRPKPPPQPLLPKPPVTKELPPLASIAQIISSVSSAPALLKTEAADASPKAASSSTGCDKSGNAKAKMTIVTAIQRDSNLPSDLTQACDPEPSPIADTGLTKKRGRKKGTKNKPKLSSGVDLESSGEFASIEKMLATTDTNKFSPFLQSTDNFKEESGQNGTSEDEKETPEDKLLRGKRNTYSDCPQKITCPYCPRVFSWASSLQRHMLTHTDSQADTEAPATGGEVLDLTSCEKEQPEEVSELPGSECSPQEEQKADSPPAEEDAEEKADEYEEGPEEDSVSNKSLDLNFASKLMDFKLAESDQSAGSSSQTERKHACDVCGKTFKFAGTLSRHKKAHIREDRKDERSSEDESKSIQDDAGAPSMQDSGLEQEESPMDLKVVESPLDCEATGKENEESESISEGEGTERKSTEKSSDDKIPKTDEAKSTAKADKRKKVCTVCNKRFWSLQDLTRHMRSHTGERPYKCQTCERTFTLKHSLVRHQRIHQKVKNTRNHGKESDKEETQSRCGEDSENESSHSGTNPISENECDFAGVVGSHPSGTRSRKESLVGAAKDVPCEEERPSGQGATADLVEPAKSTQKQPAKDQEPRGSSELERPSGFIQDLLEMHNKKSPMNHILASADSTPQLLGVE", "length": 1719, "header": "tr|A0A8V0YDK8-1|A0A8V0YDK8_CHICK Isoform 1 of Ras-responsive element-binding protein 1 OS=Gallus gallus OX=9031 GN=RREB1 PE=3 SV=1 CANONICAL=A0A8V0YDK8-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Y0G1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDK8/entry#A0A8V0Y0G1-1", "sequence": { "sequence": "MYKMRWRSLNLSFACRAASVVAVTYTQWTDTKKQLETLNSYKVTPSSPNSSDGADLSSIDAMMSAVMNVGKIAENGGTSQTVKSPSKSPAPNRIGRRNQETKEEKSSYTCPLCEKICTTQHQLTMHIRQHNTDTGGTDHSCSICGKSLSSASSLDRHMLVHSGERPYKCSVCGQSFTTNGNMHRHMKIHEKDPNSTASTTPPSPLKRKRLSSKRKFSQDAEMDREERTPAKKVVEDGQYGEGDRKEDDAYHCPVCFKDFFCKYALESHMETHPDNSLRCDICCITFRTHRGLLRHNAVIHKQLPRDPTGKPFIQNNPSIPAGFHDLGFTDFSCRKFPRISQVWCETNLRRCISEFHRFICETCNKAFPMLLALKLHTETHVMDQGRDKHKLQSTSLPSENPDQKAFMASLGLQYTKDIKPVKQEDDTQDEVQEMRLRALKSNLPQEPGSTGLLSLSPLEAATMGGPFSVLPPTKENIKLLSLQPFQKGFIIQPDSSIVVKPISNESAIELADIQQILKMASSAPPQISLPPLSKAPSVPVQSIFKHMPPLKPKPLVTPRTVVATSTPPPLISAQQASPGCISPSLPPPPLRLIKNSVETSSNSHLSQPGAKSSPSSQLLLQPKVEPLTQHEMKTQLEQDSIIEALLPLNMEAKIKQEVTEGDLKAIIAGAANKKAPTMRKVLYPCRFCDQVFAFSGVLRAHIRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERPYICKICHYPFTVKANCERHLRKKHLKVTRKDIEKNIEYVTSNAAEMVDAFCSPDTVCKLCGEDLKHYRALRIHMRTHSGCQKKKPFECKECGTAFSAKRNCIHHILKQHLHVQEREIENYILVVDCSAQESHTDAPLLEDSTYMDCKPITPFLEPQNGFLLGTSSHVPIKLEPMGNFPMDFDEPLDFSQKSKNLSAVQVKQENLLVSSPLSFYDCSMEPIDLSIPKVLKRDNDIPGEARNQELASSVITDNAYNCQQCPLGFGANGNSEKNRAVGHPQPLKGSLHLTVPIISPALLGNSALLRPLRPKPPPQPLLPKPPVTKELPPLASIAQIISSVSSAPALLKTEAADASPKAASSSTGCDKSGNAKAKMTIVTAIQRDSNLPSDLTQACDPEPSPIADTGLTKKRGRKKGTKNKPKLSSGVDLESSGEFASIEKMLATTDTNKFSPFLQSTDNFKEESGQNGTSEDEKETPEDKLLRGKRNTYSDCPQKITCPYCPRVFSWASSLQRHMLTHTDSQADTEAPATGGEVLDLTSCEKEQPEEVSELPGSECSPQEEQKADSPPAEEDAEEKADEYEEGPEEDSVSNKSLDLNFASKLMDFKLAESDQSAGSSSQTERKHACDVCGKTFKFAGTLSRHKKAHIREDRKDERSSEDESKSIQDDAGAPSMQDSGLEQEESPMDLKVVESPLDCEATGKENEESESISEGEGTERKSTEKSSDDKIPKTDEAKSTAKADKRKKVCTVCNKRFWSLQDLTRHMRSHTGERPYKCQTCERTFTLKHSLVRHQRIHQKVKNTRNHGKESDKEETQSRCGEDSENESSHSGTNPISENECDFAGVVGSHPSGTRSRKESLVGAAKDVPCEEERPSGQGATADLVEPAKSTQKQPAKDQEPRGSSELERPSGFIQDLLEMHNKKSPMNHILASADSTPQLLGVE", "length": 1676, "header": "tr|A0A8V0Y0G1-1|A0A8V0Y0G1_CHICK Computationally mapped isoform of Ras-responsive element-binding protein 1 OS=Gallus gallus OX=9031 GN=RREB1 PE=3 SV=1 CANONICAL=A0A8V0YDK8-1" }, "locus": { "chromosome": "2", "start_pos": 64446507, "end_pos": 64383522, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010024761.1", "url": "https://www.ensembl.org/id/ENSGALT00010024761.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010014041.1", "url": "https://www.ensembl.org/id/ENSGALP00010014041.1" } ] } }, { "isoform_ac": "A0A8V0Y6N2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDK8/entry#A0A8V0Y6N2-1", "sequence": { "sequence": "MLEVLTERGKVLEGATEEEAEEPDATKPTTLSEETSKQEESLSQSGDSNEEKQLETLNSYKVTPSSPNSSDGADLSSIDAMMSAVMNVGKIAENGGTSQTVKSPSKSPAPNRIGRRNQETKEEKSSYTCPLCEKICTTQHQLTMHIRQHNTDTGGTDHSCSICGKSLSSASSLDRHMLVHSGERPYKCSVCGQSFTTNGNMHRHMKIHEKDPNSTASTTPPSPLKRKRLSSKRKFSQDAEMDREERTPAKKVVEDGQYGEGDRKEDDAYHCPVCFKDFFCKYALESHMETHPDNSLRCDICCITFRTHRGLLRHNAVIHKQLPRDPTGKPFIQNNPSIPAGFHDLGFTDFSCRKFPRISQVWCETNLRRCISEFHRFICETCNKAFPMLLALKLHTETHVMDQGRDKHKLQSTSLPSENPDQKAFMASLGLQYTKDIKPVKQEDDTQDEVQEMRLRALKSNLPQEPGSTGLLSLSPLEAATMGGPFSVLPPTKENIKLLSLQPFQKGFIIQPDSSIVVKPISNESAIELADIQQILKMASSAPPQISLPPLSKAPSVPVQSIFKHMPPLKPKPLVTPRTVVATSTPPPLISAQQASPGCISPSLPPPPLRLIKNSVETSSNSHLSQPGAKSSPSSQLLLQPKVEPLTQHEMKTQLEQDSIIEALLPLNMEAKIKQEVTEGDLKAIIAGAANKKAPTMRKVLYPCRFCDQVFAFSGVLRAHIRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERPYICKICHYPFTVKANCERHLRKKHLKVTRKDIEKNIEYVTSNAAEMVDAFCSPDTVCKLCGEDLKHYRALRIHMRTHSGCQKKKPFECKECGTAFSAKRNCIHHILKQHLHVQEREIENYILVVDCSAQESHTDAPLLEDSTYMDCKPITPFLEPQNGFLLGTSSHVPIKLEPMGNFPMDFDEPLDFSQKSKNLSAVQVKQENLLVSSPLSFYDCSMEPIDLSIPKVLKRDNDIPGEARNQELASSVITDNAYNCQQCPLGFGANGNSEKNRAVGHPQPLKGSLHLTVPIISPALLGNSALLRPLRPKPPPQPLLPKPPVTKELPPLASIAQIISSVSSAPALLKTEAADASPKAASSSTGCDKSGNAKAKMTIVTAIQRDSNLPSDLTQACDPEPSPIADTGLTKKRGRKKGTKNKPKLSSGVDLESSGEFASIEKMLATTDTNKFSPFLQSTDNFKEESGQNGTSEDEKETPEDKLLRGKRNTYSDCPQKITCPYCPRVFSWASSLQRHMLTHTDSQADTEAPATGGEVLDLTSCEKEQPEEVSELPGSECSPQEEQKADSPPAEEDAEEKADEYEEGPEEDSVSNKSLDLNFASKLMDFKLAESDQSAGSSSQTERKHACDVCGKTFKFAGTLSRHKKAHIREDRKDERSSEDESKSIQDDAGAPSMQDSGLEQEESPMDLKVVESPLDCEATGKENEESESISEGEGTERKSTEKSSDDKIPKTDEAKSTAKADKRKKVCTVCNKRFWSLQDLTRHMRSHTGERPYKCQTCERTFTLKHSLVRHQRIHQKVKNTRNHGKESDKEETQSRCGEDSENESSHSGTNPISENECDFAGVVGSHPSGTRSRKESLVGAAKDVPCEEERPSGQGATADLVEPAKSTQKQPAKDQEPRGSSELERPSGFIQDLLEMHNKKSPMNHILASADSTPQLLGVE", "length": 1695, "header": "tr|A0A8V0Y6N2-1|A0A8V0Y6N2_CHICK Computationally mapped isoform of Ras-responsive element-binding protein 1 OS=Gallus gallus OX=9031 GN=RREB1 PE=3 SV=1 CANONICAL=A0A8V0YDK8-1" }, "locus": { "chromosome": "2", "start_pos": 64449207, "end_pos": 64383522, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010024766.1", "url": "https://www.ensembl.org/id/ENSGALT00010024766.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010014043.1", "url": "https://www.ensembl.org/id/ENSGALP00010014043.1" } ] } }, { "isoform_ac": "A0A8V0Y6P5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDK8/entry#A0A8V0Y6P5-1", "sequence": { "sequence": "MMSAVMNVGKIAENGGTSQTVKSPSKSPAPNRIGRRNQETKEEKSSYTCPLCEKICTTQHQLTMHIRQHNTDTGGTDHSCSICGKSLSSASSLDRHMLVHSGERPYKCSVCGQSFTTNGNMHRHMKIHEKDPNSTASTTPPSPLKRKRLSSKRKFSQDAEMDREERTPAKKVVEDGQYGEGDRKEDDAYHCPVCFKDFFCKYALESHMETHPDNSLRCDICCITFRTHRGLLRHNAVIHKQLPRDPTGKPFIQNNPSIPAGFHDLGFTDFSCRKFPRISQVWCETNLRRCISEFHRFICETCNKAFPMLLALKLHTETHVMDQGRDKHKLQSTSLPSENPDQKAFMASLGLQYTKDIKPVKQEDDTQDEVQEMRLRALKSNLPQEPGSTGLLSLSPLEAATMGGPFSVLPPTKENIKLLSLQPFQKGFIIQPDSSIVVKPISNESAIELADIQQILKMASSAPPQISLPPLSKAPSVPVQSIFKHMPPLKPKPLVTPRTVVATSTPPPLISAQQASPGCISPSLPPPPLRLIKNSVETSSNSHLSQPGAKSSPSSQLLLQPKVEPLTQHEMKTQLEQDSIIEALLPLNMEAKIKQEVTEGDLKAIIAGAANKKAPTMRKVLYPCRFCDQVFAFSGVLRAHIRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERPYICKICHYPFTVKANCERHLRKKHLKVTRKDIEKNIEYVTSNAAEMVDAFCSPDTVCKLCGEDLKHYRALRIHMRTHSGCQKKKPFECKECGTAFSAKRNCIHHILKQHLHVQEREIENYILVVDCSAQESHTDAPLLEDSTYMDCKPITPFLEPQNGFLLGTSSHVPIKLEPMGNFPMDFDEPLDFSQKSKNLSAVQVKQENLLVSSPLSFYDCSMEPIDLSIPKVLKRDNDIPGEARNQELASSVITDNAYNCQQCPLGFGANGNSEKNRAVGHPQPLKGSLHLTVPIISPALLGNSALLRPLRPKPPPQPLLPKPPVTKELPPLASIAQIISSVSSAPALLKTEAADASPKAASSSTGCDKSGNAKAKMTIVTAIQRDSNLPSDLTQACDPEPSPIADTGLTKKRGRKKGTKNKPKLSSGVDLESSGEFASIEKMLATTDTNKFSPFLQSTDNFKEESGQNGTSEDEKETPEDKLLRGKRNTYSDCPQKITCPYCPRVFSWASSLQRHMLTHTDSQADTEAPATGGEVLDLTSCEKEQPEEVSELPGSECSPQEEQKADSPPAEEDAEEKADEYEEGPEEDSVSNKSLDLNFASKLMDFKLAESDQSAGSSSQTERKHACDVCGKTFKFAGTLSRHKKAHIREDRKDERSSEDESKSIQDDAGAPSMQDSGLEQEESPMDLKVVESPLDCEATGKENEESESISEGEGTERKSTEKSSDDKIPKTDEAKSTAKADKRKKVCTVCNKRFWSLQDLTRHMRSHTGERPYKCQTCERTFTLKHSLVRHQRIHQKVKNTRNHGKESDKEETQSRCGEDSENESSHSGTNPISENECDFAGVVGSHPSGTRSRKESLVGAAKDVPCEEERPSGQGATADLVEPAKSTQKQPAKDQEPRGSSELERPSGFIQDLLEMHNKKSPMNHILASADSTPQLLGVE", "length": 1615, "header": "tr|A0A8V0Y6P5-1|A0A8V0Y6P5_CHICK Computationally mapped isoform of Ras-responsive element-binding protein 1 OS=Gallus gallus OX=9031 GN=RREB1 PE=3 SV=1 CANONICAL=A0A8V0YDK8-1" }, "locus": { "chromosome": "2", "start_pos": 64445708, "end_pos": 64383522, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010024789.1", "url": "https://www.ensembl.org/id/ENSGALT00010024789.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010014053.1", "url": "https://www.ensembl.org/id/ENSGALP00010014053.1" } ] } }, { "isoform_ac": "A0A8V0Y6Q0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDK8/entry#A0A8V0Y6Q0-1", "sequence": { "sequence": "MSRRKQPSPSKVRQKQLETLNSYKVTPSSPNSSDGADLSSIDAMMSAVMNVGKIAENGGTSQTVKSPSKSPAPNRIGRRNQETKEEKSSYTCPLCEKICTTQHQLTMHIRQHNTDTGGTDHSCSICGKSLSSASSLDRHMLVHSGERPYKCSVCGQSFTTNGNMHRHMKIHEKDPNSTASTTPPSPLKRKRLSSKRKFSQDAEMDREERTPAKKVVEDGQYGEGDRKEDDAYHCPVCFKDFFCKYALESHMETHPDNSLRCDICCITFRTHRGLLRHNAVIHKQLPRDPTGKPFIQNNPSIPAGFHDLGFTDFSCRKFPRISQVWCETNLRRCISEFHRFICETCNKAFPMLLALKLHTETHVMDQGRDKHKLQSTSLPSENPDQKAFMASLGLQYTKDIKPVKQEDDTQDEVQEMRLRALKSNLPQEPGSTGLLSLSPLEAATMGGPFSVLPPTKENIKLLSLQPFQKGFIIQPDSSIVVKPISNESAIELADIQQILKMASSAPPQISLPPLSKAPSVPVQSIFKHMPPLKPKPLVTPRTVVATSTPPPLISAQQASPGCISPSLPPPPLRLIKNSVETSSNSHLSQPGAKSSPSSQLLLQPKVEPLTQHEMKTQLEQDSIIEALLPLNMEAKIKQEVTEGDLKAIIAGAANKKAPTMRKVLYPCRFCDQVFAFSGVLRAHIRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERPYICKICHYPFTVKANCERHLRKKHLKVTRKDIEKNIEYVTSNAAEMVDAFCSPDTVCKLCGEDLKHYRALRIHMRTHSGCQKKKPFECKECGTAFSAKRNCIHHILKQHLHVQEREIENYILVVDCSAQESHTDAPLLEDSTYMDCKPITPFLEPQNGFLLGTSSHVPIKLEPMGNFPMDFDEPLDFSQKSKNLSAVQVKQENLLVSSPLSFYDCSMEPIDLSIPKVLKRDNDIPGEARNQELASSVITDNAYNCQQCPLGFGANGNSEKNRAVGHPQPLKGSLHLTVPIISPALLGNSALLRPLRPKPPPQPLLPKPPVTKELPPLASIAQIISSVSSAPALLKTEAADASPKAASSSTGCDKSGNAKAKMTIVTAIQRDSNLPSDLTQACDPEPSPIADTGLTKKRGRKKGTKNKPKLSSGVDLESSGEFASIEKMLATTDTNKFSPFLQSTDNFKEESGQNGTSEDEKETPEDKLLRGKRNTYSDCPQKITCPYCPRVFSWASSLQRHMLTHTDSQADTEAPATGGEVLDLTSCEKEQPEEVSELPGSECSPQEEQKADSPPAEEDAEEKADEYEEGPEEDSVSNKSLDLNFASKLMDFKLAESDQSAGSSSQTERKHACDVCGKTFKFAGTLSRHKKAHIREDRKDERSSEDESKSIQDDAGAPSMQDSGLEQEESPMDLKVVESPLDCEATGKENEESESISEGEGTERKSTEKSSDDKIPKTDEAKSTAKADKRKKVCTVCNKRFWSLQDLTRHMRSHTGERPYKCQTCERTFTLKHSLVRHQRIHQKVKNTRNHGKESDKEETQSRCGEDSENESSHSGTNPISENECDFAGVVGSHPSGTRSRKESLVGAAKDVPCEEERPSGQGATADLVEPAKSTQKQPAKDQEPRGSSELERPSGFIQDLLEMHNKKSPMNHILASADSTPQLLGVE", "length": 1658, "header": "tr|A0A8V0Y6Q0-1|A0A8V0Y6Q0_CHICK Computationally mapped isoform of Ras-responsive element-binding protein 1 OS=Gallus gallus OX=9031 GN=RREB1 PE=3 SV=1 CANONICAL=A0A8V0YDK8-1" }, "locus": { "chromosome": "2", "start_pos": 64502937, "end_pos": 64383522, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010024796.1", "url": "https://www.ensembl.org/id/ENSGALT00010024796.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010014058.1", "url": "https://www.ensembl.org/id/ENSGALP00010014058.1" } ] } }, { "isoform_ac": "A0A8V0Y8X7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDK8/entry#A0A8V0Y8X7-1", "sequence": { "sequence": "MDAGKIQYSAWAQLQGSQVLEGATEEEAEEPDATKPTTLSEETSKQEESLSQSGDSNEEKQLETLNSYKVTPSSPNSSDGADLSSIDAMMSAVMNVGKIAENGGTSQTVKSPSKSPAPNRIGRRNQETKEEKSSYTCPLCEKICTTQHQLTMHIRQHNTDTGGTDHSCSICGKSLSSASSLDRHMLVHSGERPYKCSVCGQSFTTNGNMHRHMKIHEKDPNSTASTTPPSPLKRKRLSSKRKFSQDAEMDREERTPAKKVVEDGQYGEGDRKEDDAYHCPVCFKDFFCKYALESHMETHPDNSLRCDICCITFRTHRGLLRHNAVIHKQLPRDPTGKPFIQNNPSIPAGFHDLGFTDFSCRKFPRISQVWCETNLRRCISEFHRFICETCNKAFPMLLALKLHTETHVMDQGRDKHKLQSTSLPSENPDQKAFMASLGLQYTKDIKPVKQEDDTQDEVQEMRLRALKSNLPQEPGSTGLLSLSPLEAATMGGPFSVLPPTKENIKLLSLQPFQKGFIIQPDSSIVVKPISNESAIELADIQQILKMASSAPPQISLPPLSKAPSVPVQSIFKHMPPLKPKPLVTPRTVVATSTPPPLISAQQASPGCISPSLPPPPLRLIKNSVETSSNSHLSQPGAKSSPSSQLLLQPKVEPLTQHEMKTQLEQDSIIEALLPLNMEAKIKQEVTEGDLKAIIAGAANKKAPTMRKVLYPCRFCDQVFAFSGVLRAHIRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERPYICKICHYPFTVKANCERHLRKKHLKVTRKDIEKNIEYVTSNAAEMVDAFCSPDTVCKLCGEDLKHYRALRIHMRTHSGCQKKKPFECKECGTAFSAKRNCIHHILKQHLHVQEREIENYILVVDCSAQESHTDAPLLEDSTYMDCKPITPFLEPQNGFLLGTSSHVPIKLEPMGNFPMDFDEPLDFSQKSKNLSAVQVKQENLLVSSPLSFYDCSMEPIDLSIPKVLKRDNDIPGEARNQELASSVITDNAYNCQQCPLGFGANGNSEKNRAVGHPQPLKGSLHLTVPIISPALLGNSALLRPLRPKPPPQPLLPKPPVTKELPPLASIAQIISSVSSAPALLKTEAADASPKAASSSTGCDKSGNAKAKMTIVTAIQRDSNLPSDLTQACDPEPSPIADTGLTKKRGRKKGTKNKPKLSSGVDLESSGEFASIEKMLATTDTNKFSPFLQSTDNFKEESGQNGTSEDEKETPEDKLLRGKRNTYSDCPQKITCPYCPRVFSWASSLQRHMLTHTDSQADTEAPATGGEVLDLTSCEKEQPEEVSELPGSECSPQEEQKADSPPAEEDAEEKADEYEEGPEEDSVSNKSLDLNFASKLMDFKLAESDQSAGSSSQTERKHACDVCGKTFKFAGTLSRHKKAHIREDRKDERSSEDESKSIQDDAGAPSMQDSGLEQEESPMDLKVVESPLDCEATGKENEESESISEGEGTERKSTEKSSDDKIPKTDEAKSTAKADKRKKVCTVCNKRFWSLQDLTRHMRSHTGERPYKCQTCERTFTLKHSLVRHQRIHQKVKNTRNHGKESDKEETQSRCGEDSENESSHSGTNPISENECDFAGVVGSHPSGTRSRKESLVGAAKDVPCEEERPSGQGATADLVEPAKSTQKQPAKDQEPRGSSELERPSGFIQDLLEMHNKKSPMNHILASADSTPQLLGVE", "length": 1703, "header": "tr|A0A8V0Y8X7-1|A0A8V0Y8X7_CHICK Computationally mapped isoform of Ras-responsive element-binding protein 1 OS=Gallus gallus OX=9031 GN=RREB1 PE=3 SV=1 CANONICAL=A0A8V0YDK8-1" }, "locus": { "chromosome": "2", "start_pos": 64461173, "end_pos": 64383522, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010024770.1", "url": "https://www.ensembl.org/id/ENSGALT00010024770.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010014044.1", "url": "https://www.ensembl.org/id/ENSGALP00010014044.1" } ] } }, { "isoform_ac": "A0A8V0Y8Y2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDK8/entry#A0A8V0Y8Y2-1", "sequence": { "sequence": "MLEGATEEEAEEPDATKPTTLSEETSKQEESLSQSGDSNEEKQLETLNSYKVTPSSPNSSDGADLSSIDAMMSAVMNVGKIAENGGTSQTVKSPSKSPAPNRIGRRNQETKEEKSSYTCPLCEKICTTQHQLTMHIRQHNTDTGGTDHSCSICGKSLSSASSLDRHMLVHSGERPYKCSVCGQSFTTNGNMHRHMKIHEKDPNSTASTTPPSPLKRKRLSSKRKFSQDAEMDREERTPAKKVVEDGQYGEGDRKEDDAYHCPVCFKDFFCKYALESHMETHPDNSLRCDICCITFRTHRGLLRHNAVIHKQLPRDPTGKPFIQNNPSIPAGFHDLGFTDFSCRKFPRISQVWCETNLRRCISEFHRFICETCNKAFPMLLALKLHTETHVMDQGRDKHKLQSTSLPSENPDQKAFMASLGLQYTKDIKPVKQEDDTQDEVQEMRLRALKSNLPQEPGSTGLLSLSPLEAATMGGPFSVLPPTKENIKLLSLQPFQKGFIIQPDSSIVVKPISNESAIELADIQQILKMASSAPPQISLPPLSKAPSVPVQSIFKHMPPLKPKPLVTPRTVVATSTPPPLISAQQASPGCISPSLPPPPLRLIKNSVETSSNSHLSQPGAKSSPSSQLLLQPKVEPLTQHEMKTQLEQDSIIEALLPLNMEAKIKQEVTEGDLKAIIAGAANKKAPTMRKVLYPCRFCDQVFAFSGVLRAHIRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERPYICKICHYPFTVKANCERHLRKKHLKVTRKDIEKNIEYVTSNAAEMVDAFCSPDTVCKLCGEDLKHYRALRIHMRTHSGCQKKKPFECKECGTAFSAKRNCIHHILKQHLHVQEREIENYILVVDCSAQESHTDAPLLEDSTYMDCKPITPFLEPQNGFLLGTSSHVPIKLEPMGNFPMDFDEPLDFSQKSKNLSAVQVKQENLLVSSPLSFYDCSMEPIDLSIPKVLKRDNDIPGEARNQELASSVITDNAYNCQQCPLGFGANGNSEKNRAVGHPQPLKGSLHLTVPIISPALLGNSALLRPLRPKPPPQPLLPKPPVTKELPPLASIAQIISSVSSAPALLKTEAADASPKAASSSTGCDKSGNAKAKMTIVTAIQRDSNLPSDLTQACDPEPSPIADTGLTKKRGRKKGTKNKPKLSSGVDLESSGEFASIEKMLATTDTNKFSPFLQSTDNFKEESGQNGTSEDEKETPEDKLLRGKRNTYSDCPQKITCPYCPRVFSWASSLQRHMLTHTDSQADTEAPATGGEVLDLTSCEKEQPEEVSELPGSECSPQEEQKADSPPAEEDAEEKADEYEEGPEEDSVSNKSLDLNFASKLMDFKLAESDQSAGSSSQTERKHACDVCGKTFKFAGTLSRHKKAHIREDRKDERSSEDESKSIQDDAGAPSMQDSGLEQEESPMDLKVVESPLDCEATGKENEESESISEGEGTERKSTEKSSDDKIPKTDEAKSTAKADKRKKVCTVCNKRFWSLQDLTRHMRSHTGERPYKCQTCERTFTLKHSLVRHQRIHQKVKNTRNHGKESDKEETQSRCGEDSENESSHSGTNPISENECDFAGVVGSHPSGTRSRKESLVGAAKDVPCEEERPSGQGATADLVEPAKSTQKQPAKDQEPRGSSELERPSGFIQDLLEMHNKKSPMNHILASADSTPQLLGVE", "length": 1685, "header": "tr|A0A8V0Y8Y2-1|A0A8V0Y8Y2_CHICK Computationally mapped isoform of Ras-responsive element-binding protein 1 OS=Gallus gallus OX=9031 GN=RREB1 PE=3 SV=1 CANONICAL=A0A8V0YDK8-1" }, "locus": { "chromosome": "2", "start_pos": 64494555, "end_pos": 64383522, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010024778.1", "url": "https://www.ensembl.org/id/ENSGALT00010024778.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010014049.1", "url": "https://www.ensembl.org/id/ENSGALP00010014049.1" } ] } }, { "isoform_ac": "A0A8V0Y8Y7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDK8/entry#A0A8V0Y8Y7-1", "sequence": { "sequence": "MSRRKQPSPSKVRLLEGATEEEAEEPDATKPTTLSEETSKQEESLSQSGDSNEEKQLETLNSYKVTPSSPNSSDGADLSSIDAMMSAVMNVGKIAENGGTSQTVKSPSKSPAPNRIGRRNQETKEEKSSYTCPLCEKICTTQHQLTMHIRQHNTDTGGTDHSCSICGKSLSSASSLDRHMLVHSGERPYKCSVCGQSFTTNGNMHRHMKIHEKDPNSTASTTPPSPLKRKRLSSKRKFSQDAEMDREERTPAKKVVEDGQYGEGDRKEDDAYHCPVCFKDFFCKYALESHMETHPDNSLRCDICCITFRTHRGLLRHNAVIHKQLPRDPTGKPFIQNNPSIPAGFHDLGFTDFSCRKFPRISQVWCETNLRRCISEFHRFICETCNKAFPMLLALKLHTETHVMDQGRDKHKLQSTSLPSENPDQKAFMASLGLQYTKDIKPVKQEDDTQDEVQEMRLRALKSNLPQEPGSTGLLSLSPLEAATMGGPFSVLPPTKENIKLLSLQPFQKGFIIQPDSSIVVKPISNESAIELADIQQILKMASSAPPQISLPPLSKAPSVPVQSIFKHMPPLKPKPLVTPRTVVATSTPPPLISAQQASPGCISPSLPPPPLRLIKNSVETSSNSHLSQPGAKSSPSSQLLLQPKVEPLTQHEMKTQLEQDSIIEALLPLNMEAKIKQEVTEGDLKAIIAGAANKKAPTMRKVLYPCRFCDQVFAFSGVLRAHIRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERPYICKICHYPFTVKANCERHLRKKHLKVTRKDIEKNIEYVTSNAAEMVDAFCSPDTVCKLCGEDLKHYRALRIHMRTHSGCQKKKPFECKECGTAFSAKRNCIHHILKQHLHVQEREIENYILVVDCSAQESHTDAPLLEDSTYMDCKPITPFLEPQNGFLLGTSSHVPIKLEPMGNFPMDFDEPLDFSQKSKNLSAVQVKQENLLVSSPLSFYDCSMEPIDLSIPKVLKRDNDIPGEARNQELASSVITDNAYNCQQCPLGFGANGNSEKNRAVGHPQPLKGSLHLTVPIISPALLGNSALLRPLRPKPPPQPLLPKPPVTKELPPLASIAQIISSVSSAPALLKTEAADASPKAASSSTGCDKSGNAKAKMTIVTAIQRDSNLPSDLTQACDPEPSPIADTGLTKKRGRKKGTKNKPKLSSGVDLESSGEFASIEKMLATTDTNKFSPFLQSTDNFKEESGQNGTSEDEKETPEDKLLRGKRNTYSDCPQKITCPYCPRVFSWASSLQRHMLTHTDSQADTEAPATGGEVLDLTSCEKEQPEEVSELPGSECSPQEEQKADSPPAEEDAEEKADEYEEGPEEDSVSNKSLDLNFASKLMDFKLAESDQSAGSSSQTERKHACDVCGKTFKFAGTLSRHKKAHIREDRKDERSSEDESKSIQDDAGAPSMQDSGLEQEESPMDLKVVESPLDCEATGKENEESESISEGEGTERKSTEKSSDDKIPKTDEAKSTAKADKRKKVCTVCNKRFWSLQDLTRHMRSHTGERPYKCQTCERTFTLKHSLVRHQRIHQKVKNTRNHGKESDKEETQSRCGEDSENESSHSGTNPISENECDFAGVVGSHPSGTRSRKESLVGAAKDVPCEEERPSGQGATADLVEPAKSTQKQPAKDQEPRGSSELERPSGFIQDLLEMHNKKSPMNHILASADSTPQLLGVE", "length": 1698, "header": "tr|A0A8V0Y8Y7-1|A0A8V0Y8Y7_CHICK Computationally mapped isoform of Ras-responsive element-binding protein 1 OS=Gallus gallus OX=9031 GN=RREB1 PE=3 SV=1 CANONICAL=A0A8V0YDK8-1" }, "locus": { "chromosome": "2", "start_pos": 64502937, "end_pos": 64383522, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010024791.1", "url": "https://www.ensembl.org/id/ENSGALT00010024791.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010014054.1", "url": "https://www.ensembl.org/id/ENSGALP00010014054.1" } ] } }, { "isoform_ac": "A0A8V0YDK8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDK8/entry#A0A8V0YDK8-1", "sequence": { "sequence": "MYCAAKATLWRRSAGSAGACVPFPLSCRLSPRLQVLEGATEEEAEEPDATKPTTLSEETSKQEESLSQSGDSNEEKQLETLNSYKVTPSSPNSSDGADLSSIDAMMSAVMNVGKIAENGGTSQTVKSPSKSPAPNRIGRRNQETKEEKSSYTCPLCEKICTTQHQLTMHIRQHNTDTGGTDHSCSICGKSLSSASSLDRHMLVHSGERPYKCSVCGQSFTTNGNMHRHMKIHEKDPNSTASTTPPSPLKRKRLSSKRKFSQDAEMDREERTPAKKVVEDGQYGEGDRKEDDAYHCPVCFKDFFCKYALESHMETHPDNSLRCDICCITFRTHRGLLRHNAVIHKQLPRDPTGKPFIQNNPSIPAGFHDLGFTDFSCRKFPRISQVWCETNLRRCISEFHRFICETCNKAFPMLLALKLHTETHVMDQGRDKHKLQSTSLPSENPDQKAFMASLGLQYTKDIKPVKQEDDTQDEVQEMRLRALKSNLPQEPGSTGLLSLSPLEAATMGGPFSVLPPTKENIKLLSLQPFQKGFIIQPDSSIVVKPISNESAIELADIQQILKMASSAPPQISLPPLSKAPSVPVQSIFKHMPPLKPKPLVTPRTVVATSTPPPLISAQQASPGCISPSLPPPPLRLIKNSVETSSNSHLSQPGAKSSPSSQLLLQPKVEPLTQHEMKTQLEQDSIIEALLPLNMEAKIKQEVTEGDLKAIIAGAANKKAPTMRKVLYPCRFCDQVFAFSGVLRAHIRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERPYICKICHYPFTVKANCERHLRKKHLKVTRKDIEKNIEYVTSNAAEMVDAFCSPDTVCKLCGEDLKHYRALRIHMRTHSGCQKKKPFECKECGTAFSAKRNCIHHILKQHLHVQEREIENYILVVDCSAQESHTDAPLLEDSTYMDCKPITPFLEPQNGFLLGTSSHVPIKLEPMGNFPMDFDEPLDFSQKSKNLSAVQVKQENLLVSSPLSFYDCSMEPIDLSIPKVLKRDNDIPGEARNQELASSVITDNAYNCQQCPLGFGANGNSEKNRAVGHPQPLKGSLHLTVPIISPALLGNSALLRPLRPKPPPQPLLPKPPVTKELPPLASIAQIISSVSSAPALLKTEAADASPKAASSSTGCDKSGNAKAKMTIVTAIQRDSNLPSDLTQACDPEPSPIADTGLTKKRGRKKGTKNKPKLSSGVDLESSGEFASIEKMLATTDTNKFSPFLQSTDNFKEESGQNGTSEDEKETPEDKLLRGKRNTYSDCPQKITCPYCPRVFSWASSLQRHMLTHTDSQADTEAPATGGEVLDLTSCEKEQPEEVSELPGSECSPQEEQKADSPPAEEDAEEKADEYEEGPEEDSVSNKSLDLNFASKLMDFKLAESDQSAGSSSQTERKHACDVCGKTFKFAGTLSRHKKAHIREDRKDERSSEDESKSIQDDAGAPSMQDSGLEQEESPMDLKVVESPLDCEATGKENEESESISEGEGTERKSTEKSSDDKIPKTDEAKSTAKADKRKKVCTVCNKRFWSLQDLTRHMRSHTGERPYKCQTCERTFTLKHSLVRHQRIHQKVKNTRNHGKESDKEETQSRCGEDSENESSHSGTNPISENECDFAGVVGSHPSGTRSRKESLVGAAKDVPCEEERPSGQGATADLVEPAKSTQKQPAKDQEPRGSSELERPSGFIQDLLEMHNKKSPMNHILASADSTPQLLGVE", "length": 1719, "header": "tr|A0A8V0YDK8-1|A0A8V0YDK8_CHICK Isoform 1 of Ras-responsive element-binding protein 1 OS=Gallus gallus OX=9031 GN=RREB1 PE=3 SV=1 CANONICAL=A0A8V0YDK8-1" }, "locus": { "chromosome": "2", "start_pos": 64463253, "end_pos": 64383522, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010024774.1", "url": "https://www.ensembl.org/id/ENSGALT00010024774.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010014047.1", "url": "https://www.ensembl.org/id/ENSGALP00010014047.1" } ] } }, { "isoform_ac": "A0A8V0YDL4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDK8/entry#A0A8V0YDL4-1", "sequence": { "sequence": "MEFEKELSSVLEGATEEEAEEPDATKPTTLSEETSKQEESLSQSGDSNEEKQLETLNSYKVTPSSPNSSDGADLSSIDAMMSAVMNVGKIAENGGTSQTVKSPSKSPAPNRIGRRNQETKEEKSSYTCPLCEKICTTQHQLTMHIRQHNTDTGGTDHSCSICGKSLSSASSLDRHMLVHSGERPYKCSVCGQSFTTNGNMHRHMKIHEKDPNSTASTTPPSPLKRKRLSSKRKFSQDAEMDREERTPAKKVVEDGQYGEGDRKEDDAYHCPVCFKDFFCKYALESHMETHPDNSLRCDICCITFRTHRGLLRHNAVIHKQLPRDPTGKPFIQNNPSIPAGFHDLGFTDFSCRKFPRISQVWCETNLRRCISEFHRFICETCNKAFPMLLALKLHTETHVMDQGRDKHKLQSTSLPSENPDQKAFMASLGLQYTKDIKPVKQEDDTQDEVQEMRLRALKSNLPQEPGSTGLLSLSPLEAATMGGPFSVLPPTKENIKLLSLQPFQKGFIIQPDSSIVVKPISNESAIELADIQQILKMASSAPPQISLPPLSKAPSVPVQSIFKHMPPLKPKPLVTPRTVVATSTPPPLISAQQASPGCISPSLPPPPLRLIKNSVETSSNSHLSQPGAKSSPSSQLLLQPKVEPLTQHEMKTQLEQDSIIEALLPLNMEAKIKQEVTEGDLKAIIAGAANKKAPTMRKVLYPCRFCDQVFAFSGVLRAHIRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERPYICKICHYPFTVKANCERHLRKKHLKVTRKDIEKNIEYVTSNAAEMVDAFCSPDTVCKLCGEDLKHYRALRIHMRTHSGCQKKKPFECKECGTAFSAKRNCIHHILKQHLHVQEREIENYILVVDCSAQESHTDAPLLEDSTYMDCKPITPFLEPQNGFLLGTSSHVPIKLEPMGNFPMDFDEPLDFSQKSKNLSAVQVKQENLLVSSPLSFYDCSMEPIDLSIPKVLKRDNDIPGEARNQELASSVITDNAYNCQQCPLGFGANGNSEKNRAVGHPQPLKGSLHLTVPIISPALLGNSALLRPLRPKPPPQPLLPKPPVTKELPPLASIAQIISSVSSAPALLKTEAADASPKAASSSTGCDKSGNAKAKMTIVTAIQRDSNLPSDLTQACDPEPSPIADTGLTKKRGRKKGTKNKPKLSSGVDLESSGEFASIEKMLATTDTNKFSPFLQSTDNFKEESGQNGTSEDEKETPEDKLLRGKRNTYSDCPQKITCPYCPRVFSWASSLQRHMLTHTDSQADTEAPATGGEVLDLTSCEKEQPEEVSELPGSECSPQEEQKADSPPAEEDAEEKADEYEEGPEEDSVSNKSLDLNFASKLMDFKLAESDQSAGSSSQTERKHACDVCGKTFKFAGTLSRHKKAHIREDRKDERSSEDESKSIQDDAGAPSMQDSGLEQEESPMDLKVVESPLDCEATGKENEESESISEGEGTERKSTEKSSDDKIPKTDEAKSTAKADKRKKVCTVCNKRFWSLQDLTRHMRSHTGERPYKCQTCERTFTLKHSLVRHQRIHQKVKNTRNHGKESDKEETQSRCGEDSENESSHSGTNPISENECDFAGVVGSHPSGTRSRKESLVGAAKDVPCEEERPSGQGATADLVEPAKSTQKQPAKDQEPRGSSELERPSGFIQDLLEMHNKKSPMNHILASADSTPQLLGVE", "length": 1694, "header": "tr|A0A8V0YDL4-1|A0A8V0YDL4_CHICK Computationally mapped isoform of Ras-responsive element-binding protein 1 OS=Gallus gallus OX=9031 GN=RREB1 PE=3 SV=1 CANONICAL=A0A8V0YDK8-1" }, "locus": { "chromosome": "2", "start_pos": 64465392, "end_pos": 64383522, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010024782.1", "url": "https://www.ensembl.org/id/ENSGALT00010024782.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010014052.1", "url": "https://www.ensembl.org/id/ENSGALP00010014052.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:395920", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:395920", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2K4K0-1", "protein_name": "Ras-responsive element-binding protein 1", "gene_name": "Rreb1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTSNPPTGLEGSDLSSVNTMMSAVMSISSVTENGGSPQGIKSPMKPPGPNRIGRRNQETKEEKSSYNCPLCEKVCTTQHQLTMHIRQHNTDTGGADHSCSICGKSLSSASSLDRHMLVHSGERPYKCTVCGQSFTTNGNMHRHMKIHEKDTNSTTAAAPPSPLKRRRLSSKRKLSHDAESEREDPGPAKKTVEDGQSSGLDKMADETFHCPVCFKEFVCKYGLETHMETHSDNPLRCDICCVTFRTHRGLLRHNALVHKQLPRDAMGRPFIQNNPSIPAGFHDLGFTDFSCRKFPRISQAWCETNLRRCISEQHRFVCDTCDKAFPMLSSLILHRQTHIPADQGREKLQTKTLAADTLDQKVFLAFLGLQHTKDVKPAPAEELLPDDSHTIQLQTLKCQLPQDPGCTNVLSLSPFEAASLGGSLTVLPATKENMKHLSLQPFQKGFIIQPDSSIVVKPISGESAIELADIQQILKMAASAPPQISLPPLSKAPATPLQAIFKHMPPLKPKPLVAPRTVVAASTPPPLINAQQASPGCISPSLPPQSLKFLKGSVEAVSSAHLLQSKSGIQPNTSTQLFLQQPGVELPGQAEMKAQLEQDSIIEALLPLNMEAKIKQEITEGDLKAIMTGPSGKKTPAMRKVLYPCRFCNQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERPYICKICHYPFTVKANCERHLRKKHLKATRKDIEKNIQYVSSSTAELVDALCSPETVCRLCGEDLKHYRALRIHMRTHCSRGLGGCHKGRKPFECKECNAAFAAKRNCIHHILKQHLHVPEKDIESYVLATDAGLGPADTAAEASSREESSCVTFAECKPLTTFLEPQNGFLHSSPTQPLPSHISVKLEPASSFATDFNEPLDFSQKGLALVQVKQENMSSLLNSSSSSALYDCSMEPIDLSIPKSGKRGDKDTVVSSDAKKPEPEAGKAEQLSPHPPPCPTLSVTVEPKGSLDNPAGTVVAVTTAAKLEPHTQPLQGSVQLAVPIYSSALISNAPLLGSSALLNSASLLRPLRPKPPLLLPKPAMTEELPPLASIAQIISSVSSAPTLLKTKAADPGPSSTSSNAVATDSPGGSIPKASPSPTDIPSSREPTDPAPTASSPEEASPPEQGPAASSRKRGRKRGMRNRPLPNSSAVDLDSSGEFASIEKMLATTDTNKFSPFLQTAEDTQEEVAGTPADHRGPTEEEQGSSAEDRLLRAKRNSYANCLQKINCPHCPRVFPWASSLQRHMLTHTGQKPFPCQKCDAFFSTKSNCERHQLRKHGVTTCSLRRNGLIPPKEGDVGSHDSTDSQSDTDTLTTPGEVLDLTARDKEQPTSEGASELSPATQDLTETEAKAEAAPPEEEEEEKGTEENPEPELECRVEESSGDADAPEEDTASNQSLDLDFATKMMDFKLAESEAGAVDSQGPAQQEPKHACNTCGKNFKFLSTLSRHRKAHGCQEPKEEEEAPSLENESLGRAVEGPSPSPEPEETPAESSATDPTAGTGEASGERQNEDTESPSDGEGTAEKRGDSDRRPKTDSPKSMASKADKRKKVCSVCNKRFWSLQDLTRHMRSHTGERPYKCQTCERTFTLKHSLVRHQRIHQKARHSKHHGKDSDKDERAEEGSEDESTHSANNPASENEAESAPSTSNHVAITRSRKESLANSGKECGREEKAIAEQATEPSAPKEPGSPGETDPQSPAAIVQDLLELCGTRPAPILAATDGASQLLGME", "length": 1751 }, "evidence": [ { "id": "A0A8V0YDK8", "url": "https://omabrowser.org/oma/group/A0A8V0YDK8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E1BN44-1", "protein_name": "Ras-responsive element-binding protein 1", "gene_name": "RREB1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MTSSSPIGLEGSDLSSINTMMSAVMSVGKVTENGGSPQSVKSPTKPPGPNRIGRRNQETKEEKSSYNCPLCEKVCTTQHQLTMHIRQHNTDTGGADHSCSICGKSLSSASSLDRHMLVHSGERPYKCTVCGQSFTTNGNMHRHMKIHEKDPNSSPAAAPPSPLKRRRLSSKRKLSHDVESEKEDPAPAKKMVEDGPLGDAERKAEEVSHCPLCFKEFVCKYGLETHLETHSDNPLRCDVCCVTFRTHRGLLRHNALVHRQLPRDALGRPFIQNNPAIPAGFHDLGFTDFSCRKFPRISQAWCETNLRRCISEQHRFICDTCDKAFPMLSSLTLHKQTHVAANQSPDRLQARAPRGDDLDQKVFLAVLGLQHAEDVRPAPAEEPPPDDNQAIQLQALRCQLPQEPGCAGLLSLAPFDAAALGGALAVLPAASDSVKHLALQPFQKGFIIQPDSSIVVKPISGEPAIELADIQQILKMAAAAPPQVGLPPLAKAPAAPLQAVFKHMPPLKPKPLAAPRTVVATSTPPPLVNTQQASPGCVSPSLPPPPLKLLKGTAEAAPGAHLLPPKSGAQLFLQPPRLELPGQAEVKTQLEQDSLLEALLPLSVEAKIKQEIAEGDLKAIVAGPGGKKAPAVRKVLYPCRFCSQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERPYICKICHYPFTVKANCERHLRKKHLKATRKDIEKNIEYVTSSTPELVDTLCSPETVCRLCGEDLKHYRALRVHMRAHCGRGLGGCPKPRKPFECKECSAAFSAKRNCIHHVLKQHLHVPERDIESYVLAADGLGPANTPAEAPGRTDEGERKPLAAFLEPQNGFLPAGPAQPLPAHVAVKVEPANNLATDFNEPLDFSQKGLALIQVKQENAAAFLSPSAPYDCSMEPIDLSIPKNFRRGDKDSAAPGEAKKPEQEPGSSEQASPGPPACPTLPATLGASGPLEKPGVPAAASSAASPLEAAALPLQGPVQLAVPLYSSALVNSSPLLGSSTLGSPALLRPLRPKPPLLLPKPPVTEELPPLASIAQIISSVSSAPTLLKTKVADPGPGGTSGTAAALDGIGGALPKATTDITSPKESSDSPPSANSPEAASPTEQGPAGLSKKRGRKRGARSRARSSGGVDLDSSGEFASIEKMLATTDTNKFSPFLQSAEDDAQDEVAAAPADHNGPSDEEQGSPPEDRLLRAKRNSYANCLQKINCPHCSRVFPWASSLQRHMLTHTGQKPFPCQKCGAFFSTKSNCERHQLRKHGVTACSLRRNGLIPQSKESDGARDSTDSQSDAEASAAGSEVLDLTARELPAPTPEGASEPSPAAAPAREDPPGGAQEEAEQVATEEDLHPEEEDAQPTEEEEGEEECAEEEPAEAADGPEEDTVSNKSLDLNLASTLMGFKLAEGEAGAQDHKHTCHVCGKSFKFLTTLSRHRKAHDREEPGDESAPPREHEGPHPADPEPPAPEPPAEAEVTPDAPAEKQSEAAEGPSDADADGDGEGPAEKRPLEKSDDDKKPKTDTPRSAASKADKRKKVCSVCSKRFWSLQDLTRHMRSHTGERPYKCQTCERTFTLKHSLVRHQRVHQKARHAKRHGRDSDREEHAEEDSESESAHSGAHPVSEGEGDAGLHASAHVALTRSRRESLAAKDAGRREERAAARTAGASQAAAGRSTPRAAAAGSPPEPAPQGDPGRESPAGLLQDLLELPGRRPAHPLLPTADSASLLGLE", "length": 1745 }, "evidence": [ { "id": "A0A8V0YDK8", "url": "https://omabrowser.org/oma/group/A0A8V0YDK8/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "G3HD91-1", "protein_name": "Ras-responsive element-binding protein 1", "gene_name": "Rreb1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MTSNSSIGLEGSDLPSINTMMSAVMSVANVTENGGSPQGIKSPTKPPGPNRIGRRNQETKEEKSSYNCPLCEKLCTTQHQLTMHIRQHNTDTGGTDHSCSICGKSLSSASSLDRHMLVHSGERPYKCTVCGQSFTTNGNMHRHMKIHEKDSCSTTAAAPPSPLKRRRLSSKRKLSHDAESEREDLAPAKKMVEDGQSGDLEKMADEVFHCPVCFKEFVCKYGLETHMETHSDNPLRCDICCVTFRTHRGLLRHNALVHKQLPRDAMGRPFIQNNPSIPAGFHDLGFTDFSCRKFPRISQAWCETNLRRCISEQHRFVCDTCDKAFPMLSSLILHRQTHIPADQGRDKLQTKTLAGDTQDQKVFLTFLGLQHTKDIRPAPPEESLLDDNQAIQLQTLKCQLPQDPGCTNVLSLSPFEAASLGGSLTVLPATKEGLKHLSLQPFQKGFIIQPDSSIVVKPISGESAIELADIQQILKMAASAPPQISLPPLSKAPATPLQAIFKHMPPLKPKPLVAPRTVVATSTPPPLINAQQASPGCISPSLPPQSLKFLKGSVEAASNIHLLQSKSGVQPNTTTQLFLQQPGVELPGQPEMKTQLEQDSIIEALLPLNMEAKIKQEITEGDLKAIMTGPSGKKTPAMRKVLYPCRFCNQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERPYICKICHYPFTVKANCERHLRKKHLKATRKDIEKNIEYVSSSAAELVDAFCSPETVCRLCGEDLKHYRALRIHMRTHCNRGLGGCHKGRKPFECKECNATFAAKRNCVHHILKQHLHVPERDIESYVLATDGGLGPTDTPTETSARGEEGSCIAFGECKPLATFLEPQNGFLHTSPNQPLPSHISVKLEPASSFAVDFNEPLDFSQKGLALVQVKQENVSSLLNSSSSALYDCSMEPIDLSIPKSIKKGDKDTVVPSDAKKPEPESGKAEQLSPCPPPCPTLSVTVEPKGSLENPTGTIVAVSTTANLEPHTQPLQGSVQLAVPIYSSALISSPPLLGNSALLNNPALLRPLRPKPPLLLPKPPMTEELPPLASIAQIISSVSSAPTLLKTKVADPGPSITSSNTVATDSLGSSIPKVITTPTDITSPKESSELPPTASSPEEALPIEQGPSGSSRKRGRKRGMRNRPLTNSGGVDLDSSGEFASIEKMLATTDTNKFSPFLQTAEDDIQDDVSGAPADHHGPSDEEQGSPAEDRLLRAKRNSYANCLQKINCPHCPRVFPWASSLQRHMLTHTGQKPFPCQKCDAFFSTKSNCERHQLRKHGVTTCSLRRNGLIPPKEGDVGSHDSTDSQSDTDALTTPGEVLDLTAQDKEQLPSEGAVELSPATQDLTVKEAKAEAAPPENEEEKSAEEKPEEECSIEESAGNTDAPEEDTASNQSLDLDFASKLMEFKLAESEAGTVDSQGTAQQDQKHTCNTCGKNFKFLGTLSRHKKAHSCQEPKEEKEAPLPENESASRATEGPSPSPEPEEKPAESPAIGPTLGTREASVEKQSEETEGPSDGEGTAEKRGSSDKTPKTDSPKSTATKADKRKKVCSVCNKRFWSLQDLTRHMRSHTGERPYKCQTCERTFTLKHSLVRHQRIHQKARHSKHHGKDSDKDERAEEDSEDESTHSANNPVSENEADSAPSTSNHVAITRSRKENSGKDCNQEEKAAAEQPSEPSHSTPKEQVSSGETDPQSPAALVQDLLELCTKRPAPILAATDSASQLLGME", "length": 1748 }, "evidence": [ { "id": "A0A8V0YDK8", "url": "https://omabrowser.org/oma/group/A0A8V0YDK8/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q3UH06-1", "protein_name": "Ras-responsive element-binding protein 1", "gene_name": "Rreb1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTSNSPIGLEGSDLSSINTMMSAVMSVASVTENGGSPQGIKSPMKPPGPNRIGRRNQETKEEKSSYNCPLCEKICTTQHQLTMHIRQHNTDTGGADHACSICGKSLSSASSLDRHMLVHSGERPYKCTVCGQSFTTNGNMHRHMKIHEKDTNSTTAAAPPSPLKRRRLSSKRKLSHDAESEDPGPAKKMVEDGQSGDLDKMSDEIFHCPVCFKEFVCKYELETHMETHSDNPLRCDICCVTFRTHRGLLRHNALVHKQLPRDAMGRPFIQNNPSIPAGFHDLGFTDFSCRKFPRISQAWCETNLRRCISEQHRFVCDTCDKAFPMLSSLILHRQSHIPADQGREKLQTKTLAAESLEQKAFLALLGLQHTKDVKPAPAEELLPDDNQAIQLQTLKYQLPQEPGCPTVLSVSPLDAASLGGSLTVLPATKENMKHLSLQPFQKGFIIQPDSSIVVKPISGESAIELADIQQILKMAASAPPQISLPPLSKAPATPLQAIFKHMPPLKPKPLVTPRTVVAASTPPPLINAQQASPGCISPSLPPQSLKFLKGSVEAVSNVHLLQSKSGIQPSTTTQLFLQQAGVELPGQPEMKTQLEQESIIEALLPLNMEAKIKQEITEGDLKAIMTGPSGKKTPAMRKVLYPCRFCNQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHIRTHSGERPYICKICHYPFTVKANCERHLRKKHLKATRKDIEKNIEYVSSPTAELVDAFCAPETVCRLCGEDLKHYRALRIHMRTHCSRGLGGCHKGRKPFECKECNAPFVAKRNCIHHILKQHLHVPEKDIESYVLATNSGLGPADTPTDAASRGEEGSCVTFAECKPLATFLEPQNGFLHSSPTQPLPSHISVKLEPASSFAMDFNEPLDFSQKGLALVQVKQENVSSLLTSSSSSALYDCSMEPIDLSIPKSVKKGDKDTVVPSDAKKPEPEAGQAEPLSPRPPPCPTLSVTVEPKGSLETPTGTVVAVTTAAKLEPHTQPLQGSVQLAVPIYSPALVSNTPLLGNSAALLNNPALLRPLRPKPPLLLPKPSMTEELPPLASIAQIISSVSSAPTLLKTKVADPGPSITSSNTVATDSPGSSIPKAAATPTDTTSSKESSEPPPAASSPEEALPTEQGPAATSSSRKRGRKRGLRNRPLPNSSAVDLDSSGEFASIEKMLATTDTNKFSPFLQTAEDDTQEEVAGAPADQHGPADEEQGSPAEDRLLRAKRNSYANCLQKINCPHCPRVFPWASSLQRHMLTHTDSQSDTDTLTTPGEVLDLTAQAKEQPPAEGASEISPASQDLAIKEAKAAAAPSEEEEEKETEENPEPEEECRVEESTGAADAPEEDTASNQSLDLDFATKLMDFKLAESEAGSVDSQGPAQQEPKHACDTCGKNFKFLGTLSRHKKAHSCQEPKEEEAAAPSLENEGVGRAVEGPSPSPEPEEKPAESLAIDPTPGTREASVAKQNEETEGPTDGEGTAEKRGDGDKRPKTDSPKSMASKADKRKKVCSVCNKRFWSLQDLTRHMRSHTGERPYKCQTCERTFTLKHSLVRHQRIHQKARHSKHHGKDSDKDERAEEDSEDESTHSATNPASENEAESAPSTSNHVAVTRSRKESLSTSGKECSPEERAAAEQAAEPSAPKEQASPGETDPQSPAAIVQDLLELCGKRPAPILAATDGASQLLGME", "length": 1700 }, "evidence": [ { "id": "A0A8V0YDK8", "url": "https://omabrowser.org/oma/group/A0A8V0YDK8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q92766-1", "protein_name": "Ras-responsive element-binding protein 1", "gene_name": "RREB1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTSSSPAGLEGSDLSSINTMMSAVMSVGKVTENGGSPQGIKSPSKPPGPNRIGRRNQETKEEKSSYNCPLCEKICTTQHQLTMHIRQHNTDTGGADHSCSICGKSLSSASSLDRHMLVHSGERPYKCTVCGQSFTTNGNMHRHMKIHEKDPNSATATAPPSPLKRRRLSSKRKLSHDAESEREDPAPAKKMVEDGQSGDLEKKADEVFHCPVCFKEFVCKYGLETHMETHSDNPLRCDICCVTFRTHRGLLRHNALVHKQLPRDAMGRPFIQNNPSIPAGFHDLGFTDFSCRKFPRISQAWCETNLRRCISEQHRFVCDTCDKAFPMLCSLALHKQTHVAADQGQEKPQATPLPGDALDQKGFLALLGLQHTKDVRPAPAEEPLPDDNQAIQLQTLKCQLPQDPGCTNLLSLSPFEAASLGGSLTVLPATKDSIKHLSLQPFQKGFIIQPDSSIVVKPISGESAIELADIQQILKMAASAPPQISLPPFSKAPAAPLQAIFKHMPPLKPKPLVTPRTVVATSTPPPLINAQQASPGCISPSLPPPPLKLLKGSVEAASNAHLLQSKSGTQPHAATRLSLQQPRAELPGQPEMKTQLEQDSIIEALLPLSMEAKIKQEITEGELKAFMTAPGGKKTPAMRKVLYPCRFCNQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERPYICKICHYPFTVKANCERHLRKKHLKATRKDIEKNIEYVSSSAAELVDAFCAPDTVCRLCGEDLKHYRALRIHMRTHCGRGLGGGHKGRKPFECKECSAAFAAKRNCIHHILKQHLHVPEQDIESYVLAADGLGPAEAPAAEASGRGEDSGCAALGDCKPLTAFLEPQNGFLHRGPTQPPPPHVSIKLEPASSFAVDFNEPLDFSQKGLALVQVKQENISFLSPSSLVPYDCSMEPIDLSIPKNFRKGDKDLATPSEAKKPEEEAGSSEQPSPCPAPGPSLPVTLGPSGILESPMAPAPAATPEPPAQPLQGPVQLAVPIYSSALVSSPPLVGSSALLSGTALLRPLRPKPPLLLPKPPVTEELPPLASIAQIISSVSSAPTLLKTKVADPGPASTGSNTTASDSLGGSVPKAATTATPAATTSPKESSEPPAPASSPEAASPTEQGPAGTSKKRGRKRGMRSRPRANSGGVDLDSSGEFASIEKMLATTDTNKFSPFLQTAEDNTQDEVAGAPADHHGPSDEEQGSPPEDKLLRAKRNSYTNCLQKITCPHCPRVFPWASSLQRHMLTHTDSQSDAETAAAAGEVLDLTSRDREQPSEGATELRQVAGDAPVEQATAETASPVHREEHGRGESHEPEEEHGTEESTGDADGAEEDASSNQSLDLDFATKLMDFKLAEGDGEAGAGGAASQEQKLACDTCGKSFKFLGTLSRHRKAHGRQEPKDEKGDGASTAEEGPQPAPEQEEKPPETPAEVVESAPGAGEAPAEKLAEETEGPSDGESAAEKRSSEKSDDDKKPKTDSPKSVASKADKRKKVCSVCNKRFWSLQDLTRHMRSHTGERPYKCQTCERTFTLKHSLVRHQRIHQKARHAKHHGKDSDKEERGEEDSENESTHSGNNAVSENEAELAPNASNHMAVTRSRKEGLASATKDCSHREEKVTAGWPSEPGQGDLNPESPAALGQDLLEPRSKRPAHPILATADGASQLVGME", "length": 1687 }, "evidence": [ { "id": "A0A8V0YDK8", "url": "https://omabrowser.org/oma/group/A0A8V0YDK8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 8, "go_terms": [ { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YDK8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDK8" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YDK8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDK8" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YDK8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDK8" } ], "pmid": "" }, { "name": "positive regulation of substrate adhesion-dependent cell spreading", "id": "GO:1900026", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1900026", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YDK8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDK8" } ], "pmid": "" }, { "name": "positive regulation of lamellipodium morphogenesis", "id": "GO:2000394", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000394", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YDK8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDK8" } ], "pmid": "" }, { "name": "positive regulation of epithelial cell migration", "id": "GO:0010634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YDK8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDK8" } ], "pmid": "" }, { "name": "positive regulation of wound healing, spreading of epidermal cells", "id": "GO:1903691", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903691", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YDK8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDK8" } ], "pmid": "" }, { "name": "positive regulation of developmental process", "id": "GO:0051094", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051094", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YDK8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDK8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YDK8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDK8" } ], "pmid": "" }, { "name": "nuclear speck", "id": "GO:0016607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016607", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YDK8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDK8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YDK8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDK8" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YDK8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDK8" } ], "pmid": "" }, { "name": "DNA-binding transcription activator activity, RNA polymerase II-specific", "id": "GO:0001228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001228", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YDK8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDK8" } ], "pmid": "" }, { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YDK8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDK8" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YDK8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDK8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1245, "end_pos": 1247, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1369, "end_pos": 1371, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1601, "end_pos": 1603, "annotation": "n_glycosylation_sequon" }, { "start_pos": 237, "end_pos": 239, "annotation": "n_glycosylation_sequon" }, { "start_pos": 547, "end_pos": 549, "annotation": "n_glycosylation_sequon" }, { "start_pos": 92, "end_pos": 94, "annotation": "n_glycosylation_sequon" }, { "start_pos": 974, 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SV=1 CANONICAL=A0A8V0YDM6-1" }, "locus": { "chromosome": "7", "start_pos": 2855649, "end_pos": 2848947, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027547.1", "url": "https://www.ensembl.org/id/ENSGALT00010027547.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015776.1", "url": "https://www.ensembl.org/id/ENSGALP00010015776.1" } ] } }, { "isoform_ac": "A0A8V0Y9W8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDM6/entry#A0A8V0Y9W8-1", "sequence": { "sequence": "MLKSQAEPIEAGRCFVQLGTVAEESQSLDEIEYNFKEAFLLFDRTGDAKITLSQVGDIVRALGQNPTNAEINKILGNPSKEEMNAKKITFEEFLPMLQAAANNKDQGTFEDFVEGLRVFDKEGNGTVMGAELRHVLATLGEKMTEEEVEELMKGQEDSNGCINYEAFVKHIMSV", "length": 174, "header": "tr|A0A8V0Y9W8-1|A0A8V0Y9W8_CHICK Computationally mapped isoform of Myosin, light chain 1, alkali; skeletal, fast OS=Gallus gallus OX=9031 GN=MYL1 PE=4 SV=1 CANONICAL=A0A8V0YDM6-1" }, "locus": { "chromosome": "7", "start_pos": 2851846, "end_pos": 2848466, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027545.1", "url": "https://www.ensembl.org/id/ENSGALT00010027545.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015775.1", "url": "https://www.ensembl.org/id/ENSGALP00010015775.1" } ] } }, { "isoform_ac": "A0A8V0YBE4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDM6/entry#A0A8V0YBE4-1", "sequence": { "sequence": "MNSTALKPLQWRISQVFGFATKALINGQASNCSNQKQIEFSKEQQDDFKEAFLLFDRTGDAKITLSQVGDIVRALGQNPTNAEINKILGNPSKEEMNAKKITFEEFLPMLQAAANNKDQGTFEDFVEGLRVFDKEGNGTVMGAELRHVLATLGEKMTEEEVEELMKGQEDSNGCINYEAFVKHIMSV", "length": 187, "header": "tr|A0A8V0YBE4-1|A0A8V0YBE4_CHICK Computationally mapped isoform of Myosin, light chain 1, alkali; skeletal, fast OS=Gallus gallus OX=9031 GN=MYL1 PE=4 SV=1 CANONICAL=A0A8V0YDM6-1" }, "locus": { "chromosome": "7", "start_pos": 2861337, "end_pos": 2848466, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027549.1", "url": "https://www.ensembl.org/id/ENSGALT00010027549.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015778.1", "url": "https://www.ensembl.org/id/ENSGALP00010015778.1" } ] } }, { "isoform_ac": "A0A8V0YDM6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDM6/entry#A0A8V0YDM6-1", "sequence": { "sequence": "MAPKKDVKKPAAAAAAAPAPAPAPAPAPAKPKEPAIDLKSIKIEFSKEQQDDFKEAFLLFDRTGDAKITLSQVGDIVRALGQNPTNAEINKILGNPSKEEMNAKKITFEEFLPMLQAAANNKDQGTFEDFVEGLRVFDKEGNGTVMGAELRHVLATLGEKMTEEEVEELMKGQEDSNGCINYEAFVKHIMSV", "length": 192, "header": "tr|A0A8V0YDM6-1|A0A8V0YDM6_CHICK Isoform 1 of Myosin, light chain 1, alkali; skeletal, fast OS=Gallus gallus OX=9031 GN=MYL1 PE=4 SV=1 CANONICAL=A0A8V0YDM6-1" }, "locus": { "chromosome": "7", "start_pos": 2865215, "end_pos": 2848466, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027551.1", "url": "https://www.ensembl.org/id/ENSGALT00010027551.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015779.1", "url": "https://www.ensembl.org/id/ENSGALP00010015779.1" } ] } }, { "isoform_ac": "A0A8V0YIB4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDM6/entry#A0A8V0YIB4-1", "sequence": { "sequence": "LHQARQILECSATLCYLLSLSAFSAVLLLLFFFLSSQLQSFSPDEINDFKEAFLLFDRTGDAKITLSQVGDIVRALGQNPTNAEINKILGNPSKEEMNAKKITFEEFLPMLQAAANNKDQGTFEDFVEGLRVFDKEGNGTVMGAELRHVLATLGEKMTEEEVEELMKGQEDSNGCINYEAFVKHIMSV", "length": 188, "header": "tr|A0A8V0YIB4-1|A0A8V0YIB4_CHICK Computationally mapped isoform of Myosin, light chain 1, alkali; skeletal, fast OS=Gallus gallus OX=9031 GN=MYL1 PE=4 SV=1 CANONICAL=A0A8V0YDM6-1" }, "locus": { "chromosome": "7", "start_pos": 2855147, "end_pos": 2848466, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027548.1", "url": "https://www.ensembl.org/id/ENSGALT00010027548.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015777.1", "url": "https://www.ensembl.org/id/ENSGALP00010015777.1" } ] } } ], "glycosylation": [], "phosphorylation": [], 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"organism": "Sus scrofa", "sequence": { "sequence": "MAPKKDVKKPAAAAAPAPAPAPAPAPAPAPPKEEKIDLSAIKYLIQNIEFSKEQQDEFKEAFLLFDRTGECKITLSQVGDVLRALGTNPTNAEVKKVLGNPSNEEMNAKKIEFEQFLPMLQAISNNKDQGSYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGEKMKEEEVEALMAGQEDSNGCINYEAFVKHIMSI", "length": 197 }, "evidence": [ { "id": "A0A8V0YDM6", "url": "https://omabrowser.org/oma/group/A0A8V0YDM6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0JNJ5-1", "protein_name": "Myosin light chain 1/3, skeletal muscle isoform", "gene_name": "MYL1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAPKKDVKKPAAAAAPAPAPAPAPAPAPAPPKEEKIDLSAIKIEFSKQQQDEFKEAFLLFDRTGECKITLSQVGDVLRALGTNPTNAEVKKVLGNPSNEEMNAKKIEFEQFLPMLQAISNNKDQGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGEKMKEEEVEALMAGQEDSNGCINYEAFVKHIMSN", "length": 192 }, "evidence": [ { "id": "A0A8V0YDM6", "url": "https://omabrowser.org/oma/group/A0A8V0YDM6/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" 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} ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YDN8-1", "uniprot_ac": "A0A8V0YDN8", "uniprot_id": "A0A8V0YDN8_CHICK", "mass": { "chemical_mass": 15665.0, "monoisotopic_mass": 15665.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "EF-hand domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A8V0YDN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDN8/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YDN8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDN8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDN8", "locus": {} } ], "crossref": [ { "id": "A0A8V0YDN8", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YDN8", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR011992", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011992", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YDN8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDN8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YDN8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDN8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSQVGRDHEDHQVELAAPHSTIQNPNPVSEGGVQTLLELHALGFWPAPFLLQMRKDKDANDKVFKNLDENGDSQVDRFKEFVIFMGVLICCCHNYFEHKAAKKLSKCLQDAIFACAPYAPAMDPIIPSMYCDAAYKHAGL", "length": 140, "header": "tr|A0A8V0YDN8-1|A0A8V0YDN8_CHICK Isoform 1 of EF-hand domain-containing protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0YDN8-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YDN8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDN8/entry#A0A8V0YDN8-1", "sequence": { "sequence": "MSQVGRDHEDHQVELAAPHSTIQNPNPVSEGGVQTLLELHALGFWPAPFLLQMRKDKDANDKVFKNLDENGDSQVDRFKEFVIFMGVLICCCHNYFEHKAAKKLSKCLQDAIFACAPYAPAMDPIIPSMYCDAAYKHAGL", "length": 140, "header": "tr|A0A8V0YDN8-1|A0A8V0YDN8_CHICK Isoform 1 of EF-hand domain-containing protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0YDN8-1" }, "locus": { "chromosome": "4", "start_pos": 79282494, "end_pos": 79281707, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027576.1", "url": "https://www.ensembl.org/id/ENSGALT00010027576.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015794.1", "url": "https://www.ensembl.org/id/ENSGALP00010015794.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], 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"table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YDP4-1", "uniprot_ac": "A0A8V0YDP4", "uniprot_id": "A0A8V0YDP4_CHICK", "mass": { "chemical_mass": 39053.0, "monoisotopic_mass": 39053.0 }, "refseq": { "ac": "XP_046756391", "name": "vesicular integral-membrane protein VIP36 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046756391" }, "gene_names": [ { "name": "LMAN2", "type": "recommended", "evidence": [ { "id": "A0A8V0YDP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDP4" } ] }, { "name": "LMAN2", "type": "synonym", "evidence": [ { "id": "XP_046756391", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046756391" } ] } ], "protein_names": [ { "name": "Lectin, mannose binding 2", "type": "synonym", "evidence": [ { "id": "A0A8V0YDP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDP4/entry#names_and_taxonomy" } ] }, { "name": "vesicular integral-membrane protein VIP36 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_046756391", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046756391" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052544.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_046756391", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046756391" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YDP4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDP4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LMAN2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDP4", "locus": { "chromosome": "13", "start_pos": 9713019, "end_pos": 9717372, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012047", "url": "https://www.ensembl.org/id/ENSGALG00010012047" } ] } } ], "crossref": [ { "id": "A0A8V0YDP4", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YDP4", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd06901", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06901", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100859676", "url": "https://www.ncbi.nlm.nih.gov/gene/100859676", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR005052", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005052", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013320", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013320", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035664", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035664", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051136", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051136", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "GCTADIR", "url": "https://omabrowser.org/oma/group/GCTADIR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y7G8", "url": "https://www.orthodb.org/?gene=A0A8V0Y7G8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YDP4", "url": "https://www.orthodb.org/?gene=A0A8V0YDP4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12223", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12223", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12223:SF36", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12223:SF36", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03388", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03388", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-204005", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-204005", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-5694530", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5694530", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_046756391", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046756391", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Y7G8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y7G8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y7G8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y7G8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YDP4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDP4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YDP4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDP4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAGAQLVAVALLLLAGAGPRLAPAELTDGNSEHLKREHSLMKPYQGAGSAAMPLWDFQGSTMVTSQYVRLTPDERSREGSIWNRVPCFLKDWELHVHFRIHGAGKKNLHGDGLALWYTQERLVPGPVFGSRDNFHGLAIFLDTYPNDEATELEGSCGLKALTLSLQRVFPYISAMVNNGSLTYDHSKDGRWTELAGCTAEIRNQNHDTFLAVRYSRGRLTVMTDVEDKNEWKNCIDIAGVQLPTGYFFGASAGTGDLSDNHDIISMKLFQLMVEHPLEDDTVDWTKIEPSVSLLKSPKDNVDDPTGNFRSGPLTGWKVFLLLLCALLGIIVCAVVGAVVFQKRQERNKRFY", "length": 352, "header": "tr|A0A8V0YDP4-1|A0A8V0YDP4_CHICK Isoform 1 of Lectin, mannose binding 2 OS=Gallus gallus OX=9031 GN=LMAN2 PE=1 SV=1 CANONICAL=A0A8V0YDP4-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Y7G8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDP4/entry#A0A8V0Y7G8-1", "sequence": { "sequence": "MAAGAQLVAVALLLLAGAGPRLAPAELTDGNSEHLKREHSLMKPYQGAGSAAMPLWDFQGSTMVTSQYVRLTPDERSREGSIWNRVPCFLKDWELHVHFRIHGAGKKNLHGDGLALWYTQERLVPGPVFGSRDNFHGLAIFLDTYPNDEATERVFPYISAMVNNGSLTYDHSKDGRWTELAGCTAEIRNQNHDTFLAVRYSRGRLTVMTDVEDKNEWKNCIDIAGVQLPTGYFFGASAGTGDLSDNHDIISMKLFQLMVEHPLEDDTVDWTKIEPSVSLLKSPKDNVDDPTGNFRSGPLTGWKVFLLLLCALLGIIVCAVERNKRFY", "length": 327, "header": "tr|A0A8V0Y7G8-1|A0A8V0Y7G8_CHICK Computationally mapped isoform of Lectin, mannose binding 2 OS=Gallus gallus OX=9031 GN=LMAN2 PE=1 SV=1 CANONICAL=A0A8V0YDP4-1" }, "locus": { "chromosome": "13", "start_pos": 9717294, "end_pos": 9713220, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028856.1", "url": "https://www.ensembl.org/id/ENSGALT00010028856.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016615.1", "url": "https://www.ensembl.org/id/ENSGALP00010016615.1" } ] } }, { "isoform_ac": "A0A8V0YDP4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDP4/entry#A0A8V0YDP4-1", "sequence": { "sequence": "MAAGAQLVAVALLLLAGAGPRLAPAELTDGNSEHLKREHSLMKPYQGAGSAAMPLWDFQGSTMVTSQYVRLTPDERSREGSIWNRVPCFLKDWELHVHFRIHGAGKKNLHGDGLALWYTQERLVPGPVFGSRDNFHGLAIFLDTYPNDEATELEGSCGLKALTLSLQRVFPYISAMVNNGSLTYDHSKDGRWTELAGCTAEIRNQNHDTFLAVRYSRGRLTVMTDVEDKNEWKNCIDIAGVQLPTGYFFGASAGTGDLSDNHDIISMKLFQLMVEHPLEDDTVDWTKIEPSVSLLKSPKDNVDDPTGNFRSGPLTGWKVFLLLLCALLGIIVCAVVGAVVFQKRQERNKRFY", "length": 352, "header": "tr|A0A8V0YDP4-1|A0A8V0YDP4_CHICK Isoform 1 of Lectin, mannose binding 2 OS=Gallus gallus OX=9031 GN=LMAN2 PE=1 SV=1 CANONICAL=A0A8V0YDP4-1" }, "locus": { "chromosome": "13", "start_pos": 9717294, "end_pos": 9713220, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028858.1", "url": "https://www.ensembl.org/id/ENSGALT00010028858.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016617.1", "url": "https://www.ensembl.org/id/ENSGALP00010016617.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-204005", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-204005", "resource": "Reactome", "description": "COPII-mediated vesicle transport" }, { "id": "R-GGA-5694530", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5694530", "resource": "Reactome", "description": "Cargo concentration in the ER" } ], "orthologs": [ { "uniprot_canonical_ac": "F1S3D5-1", "protein_name": "Lectin, mannose binding 2", "gene_name": "LMAN2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAAAAAAGWFWLWGWGRRCPGRPGLPGPGPGPITRLLFLLLLGPVTADITDGNSEHLKREHSLIKPYQGVGSSSTLFWDFQGSTILTSQYLRLTPDERSKEGSIWNHLPCFLKDWEMHVHFKVHGAGKKNLHGDGIALWYTRDRMVPGPVFGSKDNFHGLAIFLDTYPNDETTERVFPYISVMVNNGSLSYDHSKDGRWTELAGCTADLRNRNHDTFLAVRYSRGRLTVMTDLEDKNEWKNCIDITGVRLPTGYYFGASAGTGDLSDNHDIISMKLFQLMVEHTPDEENIDWTKIEPSVNFLKSPKDNVDDPTGNFRSGPLTGWRVFLLLLCALLGIIVCAVVGAVVFQKRQERNKRFY", "length": 359 }, "evidence": [ { "id": "A0A8V0YDP4", "url": "https://omabrowser.org/oma/group/A0A8V0YDP4/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F7FPK8-1", "protein_name": "Lectin, mannose-binding 2", "gene_name": "Lman2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAAEAWLWRWGWGWGQRCPGRPGLPGPGPGPTTFLHFLLLLGLVAADITDGNSEHLKREHSLIKPYQGVGSSSMPLWDFQGSTMLTSQYVRLTPDERSKEGSIWNHQPCFLKDWEMHVHFKVHGTGKKNLHGDGIALWYTRDRLVPGPVFGSKDNFHGLAVFLDTYPNDETTERVFPYISVMVNNGSLSYDHSKDGRWSELAGCTADFRNRDHDTFLAVRYSRGRLTVMTDLEDKNEWKNCIDVTGVRLPTGYYFGASAGTGDLSDNHDLISIKLFQLTVERTPEEESIDWTKIEPGVNFLKSPKDNVDDPTGNFRGGPLTGWRVFLLLLCALLGIIVCAVVGAVVFQKRQERNKRFY", "length": 358 }, "evidence": [ { "id": "A0A8V0YDP4", "url": "https://omabrowser.org/oma/group/A0A8V0YDP4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3H177-1", "protein_name": "Vesicular integral-membrane protein VIP36", "gene_name": "Lman2", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAAEAWLWRWGWGQRCPGRPGLPGPGPGPTTLLHFLLLLGPVAADITDGNSEHLKREHSLIKPYQGVGSSSMPLWDFQGSTMLTSQYVRLTPDERSKEGSIWNHQPCFLKDWEMHVHFKVHGIGKKNLHGDGIALWYTRDRLVPGPVFGSKDNFHGLAIFLDTYPNDETTERVFPYISVMVNNGSLSYDHSKDGRWSELAGCTADFRNRDHDTFLAVRYSRGRLTVMTDLEDKNEWKNCIDITGVRLPTGYYFGASAGTGDLSDNHDIISIKLFQLMVERTPEEESIDWTKIEPGVNFLRSPKDNVDDPTGNFRSGPLTGWRVFLLLLCALLGIIVCAVVGAVVFQKRQERNKRFY", "length": 356 }, "evidence": [ { "id": "A0A8V0YDP4", "url": "https://omabrowser.org/oma/group/A0A8V0YDP4/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q12907-1", "protein_name": "Vesicular integral-membrane protein VIP36", "gene_name": "LMAN2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAEGWIWRWGWGRRCLGRPGLLGPGPGPTTPLFLLLLLGSVTADITDGNSEHLKREHSLIKPYQGVGSSSMPLWDFQGSTMLTSQYVRLTPDERSKEGSIWNHQPCFLKDWEMHVHFKVHGTGKKNLHGDGIALWYTRDRLVPGPVFGSKDNFHGLAIFLDTYPNDETTERVFPYISVMVNNGSLSYDHSKDGRWTELAGCTADFRNRDHDTFLAVRYSRGRLTVMTDLEDKNEWKNCIDITGVRLPTGYYFGASAGTGDLSDNHDIISMKLFQLMVEHTPDEESIDWTKIEPSVNFLKSPKDNVDDPTGNFRSGPLTGWRVFLLLLCALLGIVVCAVVGAVVFQKRQERNKRFY", "length": 356 }, "evidence": [ { "id": "A0A8V0YDP4", "url": "https://omabrowser.org/oma/group/A0A8V0YDP4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9DBH5-1", "protein_name": "Vesicular integral-membrane protein VIP36", "gene_name": "Lman2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAEAWLWRWGWGWGQRCPGRPGLPGPGPSPTTFLHLLLLLGPVAADITDGNSEHLKREHSLIKPYQGVGSSSMPLWDFQGSTMLTSQYVRLTPDERSKEGSIWNHQPCFLKDWEMHVHFKVHGTGKKNLHGDGIALWYTRDRLVPGPVFGSKDNFHGLAIFLDTYPNDETTERVFPYISVMVNNGSLSYDHSKDGRWSELAGCTADFRNRDHDTFLAVRYSRGRLTVMTDLEDKNEWKNCIDITGVRLPTGYYFGASAGTGDLSDNHDIISIKLFQLTVERTPEEESIDWTKIEPGVNFLKSPKDNVDDPTGNFRNGPLTGWRVFLLLLCALLGVVVCAVVGAVVFQKRQERNKRFY", "length": 358 }, "evidence": [ { "id": "A0A8V0YDP4", "url": "https://omabrowser.org/oma/group/A0A8V0YDP4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VCC2-1", "protein_name": "L-type lectin-like domain-containing protein", "gene_name": "Dmel\\CG5510", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MTKPTREHCSLALLALLVAPFVVLGEDMPREPDYMKREHSLVRPFQGVGVILPHWDFLGNTMVTSNYIRLTPDLQSKSGALWNYSPVMTRNWEVHVGFKVHGKGTELFGDGFAIWYTKERMQTGPVFGSKDHFSGLAIILDTYSNHNGPHNHQHPYLSAMVNNGSWSYDHDRDGTHTQLAGCEVRFRNVEYETLVSIRYENDILSVSTDLENRNEWKNCFVVANVELPTGYHFGMSATTGDLSDNHDIHSFKFYDLDLNVNHDEIIRRSNIIPNAKTFEPPREHKEDPKPGMSNAKIFFILLFVVVVAAAVAIFAISYFKDRNARKRFY", "length": 329 }, "evidence": [ { "id": "A0A8V0YDP4", "url": "https://omabrowser.org/oma/group/A0A8V0YDP4/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 7, "go_terms": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YDP4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDP4" } ], "pmid": "" }, { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YDP4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDP4" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YDP4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDP4" } ], "pmid": "" }, { "name": "cell surface", "id": "GO:0009986", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009986", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YDP4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDP4" } ], "pmid": "" }, { "name": "COPII-coated ER to Golgi transport vesicle", "id": "GO:0030134", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030134", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YDP4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDP4" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YDP4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDP4" } ], "pmid": "" }, { "name": "endoplasmic reticulum-Golgi intermediate compartment", "id": "GO:0005793", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005793", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YDP4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDP4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YDP4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDP4" } ], "pmid": "" }, { "name": "heat shock protein binding", "id": "GO:0031072", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031072", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YDP4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDP4" } ], "pmid": "" }, { "name": "D-mannose binding", "id": "GO:0005537", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005537", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YDP4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDP4" } ], "pmid": "" }, { "name": "carbohydrate binding", "id": "GO:0030246", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030246", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YDP4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDP4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "endoplasmic reticulum to Golgi vesicle-mediated transport", "id": "GO:0006888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006888", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YDP4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDP4" } ], "pmid": "" }, { "name": "positive regulation of phagocytosis", "id": "GO:0050766", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050766", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YDP4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDP4" } ], "pmid": "" }, { "name": "retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum", "id": "GO:0006890", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006890", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YDP4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDP4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 179, "end_pos": 181, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YDP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDP4" }, { "id": "PS51328", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51328" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "L-type lectin-like", "eco_id": "ECO_0000259", "start_pos": 33, "end_pos": 272, "start_aa": "Glu", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 179, "end_pos": 181 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YDP5-1", "uniprot_ac": "A0A8V0YDP5", "uniprot_id": "A0A8V0YDP5_CHICK", "mass": { "chemical_mass": 46978.0, "monoisotopic_mass": 46978.0 }, "refseq": {}, "gene_names": [ { "name": "KCNK3", "type": "recommended", "evidence": [ { "id": "A0A8V0YDP5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDP5" } ] } ], "protein_names": [ { "name": "Potassium two pore domain channel subfamily K member 3", "type": "synonym", "evidence": [ { "id": "A0A8V0YDP5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDP5/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YDP5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDP5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "KCNK3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDP5", "locus": { "chromosome": "3", "start_pos": 105014333, "end_pos": 105027628, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010010390", "url": "https://www.ensembl.org/id/ENSGALG00010010390" } ] } } ], "crossref": [ { "id": "A0A8V0YDP5", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YDP5", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR003092", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003092", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003280", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003280", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005406", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005406", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013099", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013099", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YDP5", "url": "https://www.orthodb.org/?gene=A0A8V0YDP5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11003", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11003", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11003:SF138", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11003:SF138", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07885", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07885", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-1299316", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1299316", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-5576886", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5576886", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YDP5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDP5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YDP5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDP5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKRQNVRTLALIMCTFTYLLVGAAVFDALESEEETAERRRLEAKSQELKSKYNLSAESYRELEWVVLKLKPHKAGVQWKFAGSFYFAITVITTIGYGHAAPSTDGGKVFCMVYALLGIPLTLVMFQSLGERINTFVRYLLHRIKKCLGMRRAEVSMANMVTIGFFSCISTLCIGAAAFSYYEHWSFFHAYYYCFITLTTIGFGDYVALQKDEALQNNPQYVAFSFVYILTGLTVIGAFLNLVVLRFMTMNAEDEKRDAEHRALLTRNGQASSVHTTDMASPAPTAVAAGGGGGGLRNVYAEVLHFQSMCSCLWYKSREKLQYSIPMIIPRDLSTSDTCVEQSHSSPGRCPETPSNRCFCNARRSAISSVSTGLHSLSAFQGLMKRRSSVVDPTPSLLCTPGLIEPHVDLVPITSHAPQAPQSSA", "length": 424, "header": "tr|A0A8V0YDP5-1|A0A8V0YDP5_CHICK Isoform 1 of Potassium two pore domain channel subfamily K member 3 OS=Gallus gallus OX=9031 GN=KCNK3 PE=3 SV=1 CANONICAL=A0A8V0YDP5-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YDP5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDP5/entry#A0A8V0YDP5-1", "sequence": { "sequence": 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"MEELENGEVSGADSLALAPATMPAADLLPGRHCHHRDSSEDLVSKGEEELGIRKKFQQKALKQTKQKKSKSAEFLMVKEERAATEGIENPAFNISSTDLSAYQTSEEEVIRHDKLHSTLAAHQQKLRLQAHAEPRGNEYSRNYFDLLMDEEINPRQCGMEVSEEDPVKFQEQILYGKLMKLLDEASKIIDSQVPVTGEDFSDSVMPVSFSKTRDLHRELGDEAIPSYIEQFEREVQNDIIMFGSFSLEQDSKHHKEASHHNKKKLQSRIHELLQRQGSQPLAAEVNGCGEVPGSSGNLAGMSTGLKGAAELCAKVDCSKIPQPIEVHIKCLRGVKDKVPKGHYTLKLSVLRCLGGGLLQWPKQEEPWARATSPVSHDGNFYNAEMYFGQSIQAVLPPRKAVKPGMVVLFELFLLRGACTWIDREVGWGVFPLCDNNFNTLEGKFKCPFLRGHYNSKVDRFKKIENLISQDLDHWLCNLYFQISKLPPDSDKQNECDMHLHLPPEFLMYSSIAEKNGASEKVKHRGPQGQPLTSTKDPDTHKGSIPTVVKEVEKQFNAAKGGEACVPEEAGRKREELKMLPAESDFYQGCCGYTDEHCGLFQLKNDQGVRHKSNWNNPPEECYQEKSSAVNDTNPEEGKASSESNFYLEELEKYTFSVCRCSAVKVKLFRRVAEHFHFGVYATFSELGAAHWRSWDFWLLVLLVLLLWFLRLYLHYCSQWLFLQSISVPVTKFKFFPHTVELCYQNSLLQTSEELVMVVVGPLTLNAGLLLMVLIRWVCQQRFDSFPSFLSKFIIALGLWTVLDPLAVFIVDSFLGRLAYSAEKPIADAAKLYWVFLRSEESGVPGAIITVMLYTVLFIISSTVLYLYFLRLHSEGWLLDVFRRIHGEEGTFFVPLDLEISIQELSYIMKRAEQWRGVNGERRMVAVYDYIWKDHGSHSGVSSCDLQPQDAICDSRGTTVYVSVFTVHLSGFQQLYRHFLRLPDGAIVEAFGDIPGVSLLGNEVSIAQEHVSKTDSVLHTSSRIELRERKKSTAKGNPITSDKR", "length": 1043, "header": "tr|A0A8V0YDT7-1|A0A8V0YDT7_CHICK Isoform 1 of Orofacial cleft 1 candidate 1 (pseudo OS=Gallus gallus OX=9031 GN=OFCC1 PE=4 SV=1 CANONICAL=A0A8V0YDT7-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Y597-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDT7/entry#A0A8V0Y597-1", "sequence": { "sequence": "MEELENGEVSGADSLALAPATMPAADLLPGRHCHHRDSSEDLVSKGEEELGIRKKFQQKALKQTKQKKSKSAEFLMVKEERAATEGIENPAFNISSTDLSAYQTSEEEVIRHDKLHSTLAAHQQKLRLQAHAEPRGNEYSRNYFDLLMDEEINPRQCGMEVSEEDPVKFQEQILYGKLMKLLDEASKIIDSQVPVTGEDFSDSVMPVSFSKTRDLHRELGDEAIPSYIEQFEREVQNDIIMFGSFSLEQDSKHHKEASHHNKKKLQSRIHELLQRQGSQPLAAEVNGCGEVPGSSGNLAGMSTGLKGAAELCAKVDCSKIPQPIEVHIKCLRGVKDKVPKGHYTLKLSVLRCLGGGLLQWPKQEEPWARATSPVSHDGNFYNAEMYFGQSIQAVLPPRKAVKPGMVVLFELFLLRGACTWIDREVGWGVFPLCDNNFNTLEGKFKCPFLRGHYNSKVDRFKKIENLISQDLDHWLCNLYFQISKLPPDSDKQNECDMHLHLPPEFLMYSSIAEKNGASEKVKHRGPQGQPLTSTKDPDTHKGSIPTVVKEVEKQFNAAKGGEACVPEEAGRKREELKMLPAESDFYQGCCGYTDEHCGLFQLKNDQGVRHKVSGLF", "length": 616, "header": "tr|A0A8V0Y597-1|A0A8V0Y597_CHICK Computationally mapped isoform of Orofacial cleft 1 candidate 1 (pseudo OS=Gallus gallus OX=9031 GN=OFCC1 PE=4 SV=1 CANONICAL=A0A8V0YDT7-1" }, "locus": { "chromosome": "2", "start_pos": 63270828, "end_pos": 63186125, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010024881.1", "url": "https://www.ensembl.org/id/ENSGALT00010024881.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010014120.1", "url": "https://www.ensembl.org/id/ENSGALP00010014120.1" } ] } }, { "isoform_ac": "A0A8V0Y949-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDT7/entry#A0A8V0Y949-1", "sequence": { "sequence": "ISLQKFQQKALKQTKQKKSKSAEFLMVKEERAATEGIENPAFNISSTDLSAYQTSEEEVIRHDKLHSTLAAHQQKLRLQAHAEPRGNEYSRNYFDLLMDEEINPRQCGMEVSEEDPVKFQEQILYGKLMKLLDEASKIIDSQVPVTGEDFSDSVMPVSFSKTRDLHRELGDEAIPSYIEQFEREVQNDIIMFGSFSLEQKPPTITKKNCNPGFMSSFKGIKWAS", "length": 224, "header": "tr|A0A8V0Y949-1|A0A8V0Y949_CHICK Computationally mapped isoform of Orofacial cleft 1 candidate 1 (pseudo OS=Gallus gallus OX=9031 GN=OFCC1 PE=4 SV=1 CANONICAL=A0A8V0YDT7-1" }, "locus": { "chromosome": "2", "start_pos": 63238449, "end_pos": 63206828, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010024875.1", "url": "https://www.ensembl.org/id/ENSGALT00010024875.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010014114.1", "url": "https://www.ensembl.org/id/ENSGALP00010014114.1" } ] } }, { "isoform_ac": "A0A8V0Y959-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDT7/entry#A0A8V0Y959-1", "sequence": { "sequence": "MEELENGEVSGADSLALAPATMPAADLLPGRHCHHRDSSEDLVSKGEEELGIRKKFQQKALKQTKQKKSKSAEFLMVKEERAATEGIENPAFNISSTDLSAYQTSEEEVIRHDKLHSTLAAHQQKLRLQAHAEPRGNEYSRNYFDLLMDEEINPRQCGMEVSEEDPVKFQEQILYGKLMKLLDEASKIIDSQVPVTGEDFSDSVMPVSFSKTRDLHRELGDEAIPSYIEQFEREVQNDIIMFGSFSLEQDSKHHKEASHHNKKKLQSRIHELLQRQGSQPLAAEVNGCGEVPGSSGNLAGMSTGLKGAAELCAKVDCSKIPQPIEVHIKCLRGVKDKVPKGHYTLKLSVLRCLGGGLLQWPKQEEPWARATSPVSHDGNFYNAEMYFGQSIQAVLPPRKAVKPGMVVLFELFLLRGACTWIDREVGWGVFPLCDNNFNTLEGKFKCPFLRGHYNSKVDRFKKIENLISQDLDHWLCNLYFQISKLPPDSDKQNECDMHLHLPPEFLMYSSIAEKNGASEKVKHRGPQGQPLTSTKDPDTHKGSIPTVVKEVEKQFNAAKGGEACVPEEAGRKREELKMLPAG", "length": 582, "header": "tr|A0A8V0Y959-1|A0A8V0Y959_CHICK Computationally mapped isoform of Orofacial cleft 1 candidate 1 (pseudo OS=Gallus gallus OX=9031 GN=OFCC1 PE=4 SV=1 CANONICAL=A0A8V0YDT7-1" }, "locus": { "chromosome": "2", "start_pos": 63263340, "end_pos": 63186125, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010024885.1", "url": "https://www.ensembl.org/id/ENSGALT00010024885.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010014124.1", "url": "https://www.ensembl.org/id/ENSGALP00010014124.1" } ] } }, { "isoform_ac": "A0A8V0Y964-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDT7/entry#A0A8V0Y964-1", "sequence": { "sequence": "MEKEKFQQKALKQTKQKKSKSAEFLMVKEERAATEGIENPAFNISSTDLSAYQTSEEEVIRHDKLHSTLAAHQQKLRLQAHAEPRGNEYSRNYFDLLMDEEINPRQCGMEVSEEDPVKFQEQILYGKLMKLLDEASKIIDSQVPVTGEDFSDSVMPVSFSKTRDLHRELGDEAIPSYIEQFEREVQNDIIMFGSFSLEQDSKHHKEASHHNKKKLQSRIHELLQRQGSQPLAAEVNGCGEVPGSSGNLAGMSTGLKGAAELCAKVDCSKIPQPIEVHIKCLRGVKDKVPKGHYTLKLSVLRCLGGGLLQWPKQEEPWARATSPVSHDGNFYNAEMYFGQSIQAVLPPRKAVKPGMVVLFELFLLRGACTWIDREVGWGVFPLCDNNFNTLEGKFKCPFLRGHYNSKVDRFKKIENLISQDLDHWLCNLYFQISKLPPDSDKQNECDMHLHLPPEFLMYSSIAEKNGASEKVKHRGPQGQPLTSTKDPDTHKGSIPTVVKEVEKQFNAAKGGEACVPEEAGRKREELKMLPAESDFYQGCCGYTDEHCGLFQLKNDQGVRHKSNWNNPPEECYQEKSSAVNDTNPEEGKASSESNFYLEELEKYTFSVCRCSAVKVKLFRRVAEHFHFGVYATFSELGAAHWRSWDFWLLVLLVLLLWFLRLYLHYCSQWLFLQSISVPVTKFKFFPHTVELCYQNSLLQTSEELVMVVVGPLTLNAGLLLMVLIRWVCQQRFDSFPSFLSKFIIALGLWTVLDPLAVFIVDSFLGRLAYSAEKPIADAAKLYWVFLRSEESGVPGAIITVMLYTVLFIISSTVLYLYFLRLHSEGWLLDVFRRIHGEEGTFFVPLDLEISIQELSYIMKRAEQWRGVNGERRMVAVYDYIWKDHGSHSGVSSCDLQPQDAICDSRGTTVYVSVFTVHLSGFQQLYRHFLRLPDGAIVEAFGDIPGVSLLGNEVSIAQEHVSKTDSVLHTSSRIELRERKKSTAKGNPITSDKR", "length": 993, "header": "tr|A0A8V0Y964-1|A0A8V0Y964_CHICK Computationally mapped isoform of Orofacial cleft 1 candidate 1 (pseudo OS=Gallus gallus OX=9031 GN=OFCC1 PE=4 SV=1 CANONICAL=A0A8V0YDT7-1" }, "locus": { "chromosome": "2", "start_pos": 63358225, "end_pos": 63201094, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010024890.1", "url": "https://www.ensembl.org/id/ENSGALT00010024890.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010014129.1", "url": "https://www.ensembl.org/id/ENSGALP00010014129.1" } ] } }, { "isoform_ac": "A0A8V0YDT7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDT7/entry#A0A8V0YDT7-1", "sequence": { "sequence": "MEELENGEVSGADSLALAPATMPAADLLPGRHCHHRDSSEDLVSKGEEELGIRKKFQQKALKQTKQKKSKSAEFLMVKEERAATEGIENPAFNISSTDLSAYQTSEEEVIRHDKLHSTLAAHQQKLRLQAHAEPRGNEYSRNYFDLLMDEEINPRQCGMEVSEEDPVKFQEQILYGKLMKLLDEASKIIDSQVPVTGEDFSDSVMPVSFSKTRDLHRELGDEAIPSYIEQFEREVQNDIIMFGSFSLEQDSKHHKEASHHNKKKLQSRIHELLQRQGSQPLAAEVNGCGEVPGSSGNLAGMSTGLKGAAELCAKVDCSKIPQPIEVHIKCLRGVKDKVPKGHYTLKLSVLRCLGGGLLQWPKQEEPWARATSPVSHDGNFYNAEMYFGQSIQAVLPPRKAVKPGMVVLFELFLLRGACTWIDREVGWGVFPLCDNNFNTLEGKFKCPFLRGHYNSKVDRFKKIENLISQDLDHWLCNLYFQISKLPPDSDKQNECDMHLHLPPEFLMYSSIAEKNGASEKVKHRGPQGQPLTSTKDPDTHKGSIPTVVKEVEKQFNAAKGGEACVPEEAGRKREELKMLPAESDFYQGCCGYTDEHCGLFQLKNDQGVRHKSNWNNPPEECYQEKSSAVNDTNPEEGKASSESNFYLEELEKYTFSVCRCSAVKVKLFRRVAEHFHFGVYATFSELGAAHWRSWDFWLLVLLVLLLWFLRLYLHYCSQWLFLQSISVPVTKFKFFPHTVELCYQNSLLQTSEELVMVVVGPLTLNAGLLLMVLIRWVCQQRFDSFPSFLSKFIIALGLWTVLDPLAVFIVDSFLGRLAYSAEKPIADAAKLYWVFLRSEESGVPGAIITVMLYTVLFIISSTVLYLYFLRLHSEGWLLDVFRRIHGEEGTFFVPLDLEISIQELSYIMKRAEQWRGVNGERRMVAVYDYIWKDHGSHSGVSSCDLQPQDAICDSRGTTVYVSVFTVHLSGFQQLYRHFLRLPDGAIVEAFGDIPGVSLLGNEVSIAQEHVSKTDSVLHTSSRIELRERKKSTAKGNPITSDKR", "length": 1043, "header": "tr|A0A8V0YDT7-1|A0A8V0YDT7_CHICK Isoform 1 of Orofacial cleft 1 candidate 1 (pseudo OS=Gallus gallus OX=9031 GN=OFCC1 PE=4 SV=1 CANONICAL=A0A8V0YDT7-1" }, "locus": { "chromosome": "2", "start_pos": 63358225, "end_pos": 63186125, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010024879.1", "url": "https://www.ensembl.org/id/ENSGALT00010024879.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010014117.1", "url": "https://www.ensembl.org/id/ENSGALP00010014117.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 630, "end_pos": 632, "annotation": "n_glycosylation_sequon" }, { "start_pos": 93, "end_pos": 95, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 630, "end_pos": 632 }, { "start_pos": 93, "end_pos": 95 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YDV9-1", "uniprot_ac": "A0A8V0YDV9", "uniprot_id": "A0A8V0YDV9_CHICK", "mass": { "chemical_mass": 11796.0, "monoisotopic_mass": 11796.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Uncharacterized protein", "type": "synonym", "evidence": [ { "id": "A0A8V0YDV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDV9/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YDV9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDV9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDV9", "locus": {} } ], "crossref": [ { "id": "A0A8V0YDV9", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YDV9", "database": "AlphaFoldDB", "categories": [] }, { "id": "A0A8V0YDV9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDV9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YDV9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDV9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSCCEHEVAETRLHALSEASAAELEALELPCNLETASSFTAEDRFLIPKRLPALENFKWDTLWMRVHRVVGPSSWSLRRTSGVTRYEDAAEAVAAAETLLFMDKL", "length": 105, "header": "tr|A0A8V0YDV9-1|A0A8V0YDV9_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0YDV9-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YDV9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDV9/entry#A0A8V0YDV9-1", "sequence": { "sequence": "MSCCEHEVAETRLHALSEASAAELEALELPCNLETASSFTAEDRFLIPKRLPALENFKWDTLWMRVHRVVGPSSWSLRRTSGVTRYEDAAEAVAAAETLLFMDKL", "length": 105, "header": "tr|A0A8V0YDV9-1|A0A8V0YDV9_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0YDV9-1" }, "locus": { "chromosome": "Z", "start_pos": 44131438, "end_pos": 44131124, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010024908.1", "url": "https://www.ensembl.org/id/ENSGALT00010024908.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010014142.1", "url": 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This record is derived from a genomic sequence (NC_052571.1) annotated using gene prediction method: Gnomon, supported by EST evidence. 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"MEAEGLEALSRHLAAKIGLIKRLLQLRGLGRREMLAEVGMEVAVLHGLLGRMEEEVNQRRQLAAALQEMRKRAEKEKWEAERLQLVKKAAKEAPLVNDAPLISDEEFESVPGYMRGRLTLAQTNAALRALHAAAASKYRLLRHPPKSLPSSSRALCHRFREEETKETQGLTFVVEADLKEFTQLKVDRTFHRIVGVLRHCRRLREVRGARLVRYVLP", "length": 217, "header": "tr|A0A8V0YDY5-1|A0A8V0YDY5_CHICK Isoform 1 of SKA complex subunit 1 OS=Gallus gallus OX=9031 GN=SKA1 PE=3 SV=1 CANONICAL=A0A8V0YDY5-1" }, "locus": { "chromosome": "W", "start_pos": 437992, "end_pos": 434948, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028944.1", "url": "https://www.ensembl.org/id/ENSGALT00010028944.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016703.1", "url": "https://www.ensembl.org/id/ENSGALP00010016703.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-141430", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-141430", "resource": "Reactome", "description": "Inactivation of APC/C via direct inhibition of the APC/C complex" }, { "id": "R-GGA-141444", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-141444", "resource": "Reactome", "description": "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" }, { "id": "R-GGA-2467813", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2467813", "resource": "Reactome", "description": "Separation of Sister Chromatids" }, { "id": "R-GGA-2500257", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2500257", "resource": "Reactome", "description": "Resolution of Sister Chromatid Cohesion" }, { "id": "R-GGA-5663220", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5663220", "resource": "Reactome", "description": "RHO GTPases Activate Formins" }, { "id": "R-GGA-9648025", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9648025", "resource": "Reactome", "description": "EML4 and NUDC in mitotic spindle formation" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A075B5S0-1", "protein_name": "Immunoglobulin heavy variable 16-1", "gene_name": "Ighv16-1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "EVQLVESGGSLGQPGGSTKLSCEEASGFTFSDHWMDWFRQAPGMRLEWLANTNHDESGKGYAESVKDRFSISRDNSENLLYLQMNSLRNEDTALYYCAR", "length": 99 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A075B603-1", "protein_name": "T cell receptor alpha variable 6D-6", "gene_name": "Trav6-6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDSSPGFVAVILLILGRTHGDSVTQTEGPVTVSESESLIINCTYSATSIAYPNLFWYVRYPGEGLQLLLKVITAGQKGSSRGFEATYNKETTSFHLQKASVQESDSAVYYCALG", "length": 114 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A075B625-1", "protein_name": "T cell receptor alpha variable 4N-3", "gene_name": "Trav4n-3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MERNLGAVLGILWVQICWVSGDKVKQSPSALSLQEGTNSALRCNFSIAATTVQWFLQNPRGSLMNLFYLVPGTKENGRLKSAFDSKESYSTLHIRDAQLEDSGTYFCAAE", "length": 110 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A075B695-1", "protein_name": "T cell receptor alpha variable 9D-3", "gene_name": "Trav9d-3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLLALLPVLGIHFLLRDAQAQSVTQPDARVTVSEGASLQLRCKYSYFGTPYLFWYVQYPRQGLQLLLKYYPGDPVVQGVNGFEAEFSKSNSSFHLRKASVHWSDWAVYFCAVS", "length": 113 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A075B6B4-1", "protein_name": "T cell receptor alpha variable 6-4", "gene_name": "Trav6-4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNTSPVLVTVMLLFMLGMRKTHGDSVTQKQGQVTLSEDDFLFINCTYSTTTYPTLLWYVQYLGQGPQLLLKVTTANNKGISRGFEATYDKGTTSFHLQKASVQESDSAVYFCALV", "length": 115 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A075B6D8-1", "protein_name": "T cell receptor alpha variable 3-3", "gene_name": "Trav3-3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "GEQVEQRPPHLSVREGDSAVITCTYTDPNSYYFFWYKQEPGASLQLLMKVFSSTEINEGQGFTVLLNKKDKRLSLNLTAAHPGDSAAYFCAV", "length": 92 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A075B759-1", "protein_name": "Peptidyl-prolyl cis-trans isomerase A-like 4E", "gene_name": "PPIAL4E", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVNSVVFFEITRDGKPLGRISIKLFADKIPKTAENFRALSTGEKGFRYKGSCFHRIIPGFMCQGGDFTRPNGTGDKSIYGEKFDDENLIRKHTGSGILSMANAGPNTNGSQFFICAAKTEWLDGKHVAFGKVKERVNIVEAMEHFGYRNSKTSKKITIADCGQF", "length": 164 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A075B767-1", "protein_name": "Peptidyl-prolyl cis-trans isomerase A-like 4H", "gene_name": "PPIAL4H", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVNSVVFFDITVDGKPLGRISIKLFADKIPKTAENFRALSTGEKGFRYKGSCFHRIIPGFMCQGGDFTRPNGTDDKSIYGEKFDDENLIRKHTGSGILSMVNAGPNTNGSQLFICTAKTEWLDGKHVAFGKVKERVNIVEAMEHFGYRNSKTSKKITIADCGQF", "length": 164 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A087WP50-1", "protein_name": "Secretoglobin, family 1B, member 15", "gene_name": "Scgb1b17", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MMLAGAVVIFGVALLLLSSWGDCGICPAMKEDVHLFLNGTSEEYVEYVKQYKDDPEILENTEKIKQCVDSTLMEEDKAHANGFIEKIEASPLC", "length": 93 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WPA9-1", "protein_name": "Secretoglobin, family 2B, member 18", "gene_name": "Scgb2b18", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKGTLLLLGLLVTGELSFQTSEACVSFFEGYASVLSGSRVWLYQELQAFDATAEEKVALEKIQSCYSEERIRNILLEPKIMEAMVASPECRSYHSFNNFRSILDFISNLLGE", "length": 112 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WPG5-1", "protein_name": "Predicted gene 13283", "gene_name": "Gm13283", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLPVHLFLVGGVMLSCSPASSLDSGKSGSLHLERSETARFLADLRSVPGHQCLRDRTDFPCPWKEGTNITQMTLGETTSCYSQSLRQVLHRFDTEASRAAWHERALDQLLSSLWRELQVLKRPREQGQSCPLPFALAIRTYFRGFFRYLKAKAHSACSWEIVRVQLQVDLPAFPLSARRGPR", "length": 182 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WPY7-1", "protein_name": "RNA binding motif protein Y-linked family member 4", "gene_name": "Rbmyf4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAETNQPGKIFIGGLNIKTRQKTLQEIFGRFGPVARVILMRDRETKKSRGFAFLTFRRLADAKNAVKEMNGVILDGKRIKVKQARRPSSLESGSKKRPPSFSRTRGASRILKCGRGGRSRARSGPSCEGNLGGDRYTPNFNVSSSGRHFAVKRNPSSKRDDPPSKR", "length": 166 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WQA9-1", "protein_name": "Secretoglobin, family 2B, member 21", "gene_name": "Scgb2b21", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKGTLLLLGLLVTGELSFQTTEACVPFFEGYASVVSGSRVWMYQEFQAFDATAEEKVALEKIQGCYREESLRNILLEPKIMEAMVASPECLSYYSSNNIRCILDLLSKLLGQ", "length": 112 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WQJ0-1", "protein_name": "Secretoglobin, family 1B, member 11", "gene_name": "Scgb1b11", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKLVAAVVILGAALLLLTSGGDCGICPAIKEDVRLFLNGTSEEYVEYVKQYKDDPVILENTAKINQCVDSTLTEKDMTHTTTFLKKIEDSLLC", "length": 93 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WQP8-1", "protein_name": "Predicted gene, 21698", "gene_name": "Gm21698", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRVNVDGRETREGRKDADLPSERNEGRRRWTWRMCMAHGQTTSPVPVKSKKQFEKEEKELIKKIQLTTEETNELRDRLIYVTKGSMNKRPYHRQTRHYKELKLKEKEIMTFLHDLEMKNMEARENNQELKKEKNFYRNLHTRILLGENLIKKKLAILQQESKEIHADWAIIQQRLVELNLSGKDEQEKTSNLEAQENQVSEAARELGLATAEEDSILQNELPCQEAPAEHHPQHPSSSSDESSSDESSYSTCPEWE", "length": 267 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WR36-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r90", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSQNEAMKTTEEVALQIVLLCQFGIGTMANILLFIHNFSPLLTGCQLRPKQVICTNMAVSSILILFMTVFPNNVFVVQRNLMNDLQCKLEYFLRMVARSINLCSTCVLSTYQFVTLLPGNFGEMMVRGRRSKVISYSCCSCWLFGVLYNVYIPMKVSGPQNTHNKTDIKSKWFCVTSGFSVGIMFLWFAHDAIFISIMIWTSVSMVLLLYRHYQRLQYIFPPHQGTRGYAEIRAAHSIAMLVVTFVSFYLLHCICFILHIVFVDSRLWLRHVGEVLTSSFPTISPLLLIFRDPSYPCSLIFNYRKPVI", "length": 309 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WR44-1", "protein_name": "BTB domain containing 35, family member 15", "gene_name": "Btbd35f15", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIHALGKTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYVLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WR49-1", "protein_name": "Secretoglobin, family 2B, member 11", "gene_name": "Scgb2b11", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKGTLLLLGLLVTGELSFQTSEACVSFFEGYASVLSGSRVWLYQELQAFDATAEEKVALEKIQGCYSEERIRNILLEPKIMEAMVASPECRSYHSLNNFRSILEFISNLLGE", "length": 112 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WSM5-1", "protein_name": "Predicted gene 29049", "gene_name": "Gm29049", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTSLKKKSRRKPSSQALGNIVGCRISYGWKEGNEPVTHWKAIILGQLPTNPSLYLVKYDGIDSVYGQELHSDERILNLKVLPHKVVFLQVRDVHLASALVCREVQHKFEGKDGSEDNWSGMVLAQVPFLQDYFYISYKKDPVLYVYQLLDDYKEGNLHIIPETPLAEARSGDDNDFLIGSWVQYTRDDGSKKFGKVVYKVLANSTVYCIKFLGDLHIYVYTLVSNIT", "length": 227 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WSN2-1", "protein_name": "BTB domain containing 35, family member 16", "gene_name": "Btbd35f16", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGKTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLLFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLNFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WUL8-1", "protein_name": "NBPF family member NBPF19", "gene_name": "NBPF19", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVVSAGPWSSEKAEMNILEINETLRPQLAEKKQQFRNLKEKCFLTQLAGFLANRQKKYKYEECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLFHSQERELTQLREKLREGRDASRSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSAPREMQKAEEKEVPEDSLEECAITYSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAIDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSIPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQDPPCPRLSRELVEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSIPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQDPPCPRLSRELVEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAIDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSIPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQDPPCPRLSRELVEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSIPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQDPPCPRLSRELVEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSIPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQDPPCPRLSRELVEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSIPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQDPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLAEKEPEVLQDPLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLAEKEPEVLQDPLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLAEKEPEVLQDPLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLNSVLMEVEEPEVLQDSLDGCYSTPSMYFELPDSFQHYRSVFYSFEEEHISFALYLDNRFFTLTVTSLHLVFQMLVIFPQ", "length": 3843 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A087WXS9-1", "protein_name": "TBC1 domain family member 3I", "gene_name": "TBC1D3I", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDVVEVAGSWWAQEREDIIMKYEKGHRAGLPEDKGPKPFRSYNNNVDHLGIVHETELPPLTAREAKQIRREISRKSKWVDMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNTEEMKMKNPGRYQIMKEKGKRSSEHIQRIDRDVSGTLRKHIFFRDRYGTKQRELLHILLAYEEYNPEVGYCRDLSHIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQEHVVATSQPKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQALMPITRIAFKVQQKRLTKTSRCGPWARFCNRFVDTWARDEDTVLKHLRASMKKLTRKQGDLPPPAKPEQGSSASRPVPASRGGKTLCKGDRQAPPGPPARFPRPIWSASPPRAPRSSTPCPGGAVREDTYPVGTQGVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDVEGPWFRHYDFRQSCWVRAISQEDQLAPCWQAEHPAERVRSAFAAPSTDSDQGTPFRARDEQQCAPTSGPCLCGLHLESSQFPPGF", "length": 549 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A087X179-1", "protein_name": "TBC1 domain family member 3E", "gene_name": "TBC1D3E", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDVVEVAGSWWAQEREDIIMKYEKGHRAGLPEDKGPKPFRSYNNNVDHLGIVHETELPPLTAREAKQIRREISRKSKWVDMLGDWEKYKSSRKLIDQAYKGMPMNIRGPMWSVLLNTEEMKLKNPGRYQIMKEKGKKSSEHIQRIDRDVSGTLRKHIFFRDRYGTKQRELLHILLAYEEYNPEVGYCRDLSHIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQEHVVATSQPKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQALMPITRIAFKVQQKRLTKTSRCGPWARFCNRFVDTWARDEDTVLKHLRASMKKLTRKKGDLPPPAKPEQGSSASRPVPASRGGKTLCKGDRQAPPGPPARFPRPIWSASPPRAPRSSTPCPGGAVREDTYPVGTQGVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDVEGPWFRHYDFRQSCWVRAISQEDQLAPCWQAEHPAERVRSAFAAPSTDSDQGTPFRARDEQQCAPTSGPCLCGLHLESSQFPPGF", "length": 549 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A0A0MQP3-1", "protein_name": "BTB domain containing 35, family member 12", "gene_name": "Btbd35f12", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDSDLSITPLEVPQGLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYVLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A0A6YW58-1", "protein_name": "Immunoglobulin heavy variable V8-2", "gene_name": "Ighv8-2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGRLTFSFLLLLPVPAYVLSQVTLKVSGPGILQPSQTLSLACTFSGISLSTSGMGLSWLRKPSGKALEWLASIWNNDNYYNPSLKSRLTISKETSNYQVFLKLTSVDTADSATYYGAWR", "length": 119 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A0A6YXW2-1", "protein_name": "Predicted gene, 20773", "gene_name": "Gm20773", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSLMKKRRRKSSSNTLRNIVGCRISHSWKEGNEPVTQWKAIVLDQLPTNPSLYLVKYDGIDSIYGLELYSDDRILNLKVLPPIVVFPQVRDAHLARALVGRAVQHKFEGKDGSEVNWRGVVLAQVPIMKDLFYITYKKDPALYAYQLLDDYKEGNLHMIPDTPPAEERSGDDSDVLIGNWVEYTRKDGSKKFGKVVYQVLANPSVYFIKFHGDIHIYVYTMVPKIFKVEKS", "length": 232 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A0A6YXX7-1", "protein_name": "Predicted gene, 20807", "gene_name": "Gm20807", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSLMKKRRRKSSSNTLRNIVGCRISHSWKEGNEPVTQWKAIVLDQLPTNPSLYLVKYDGIDSIYGLELYSDDRILNLKVLPPIVVFPQVRDAHLARALVGRAVQHTFEGKDGSEVNWRGVVLAQVPIMKDLFYITYKKDPALYAYQLLDDYKEGNLHMIPDTPPAEERSGDDSDVLIGNWVEYTRKDGSKKFGKVVYQVLANPSVYFIKFHGDIHIYVYTMVPKVLEVEKS", "length": 232 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A0B4J1J8-1", "protein_name": "T cell receptor gamma, variable 4", "gene_name": "Trgv4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKNPGSQALLPLYLPWEANLADENPLLKVVIFLCLLTFGHGKLEQPEISISRPRDETAQISCKVFIESFRSVTIHWYRQKPNQGLEFLLYVLATPTHIFLDKEYKKMEASKNPSASTSILTIYSLEEEDEAIYYCSYG", "length": 138 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A0G2JE01-1", "protein_name": "Predicted gene, 21663", "gene_name": "Gm21663", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRVNVDGRETREGRKDADPPSERNEGRRRWTWRMCMAHRQTTSPVPVKSKKQFEKEEKELIKKIQLTTEETNELRDRLIYVTEGSMNKRPYHRQTRHYKELKLKEKEIMTFLHDLEMKNMEARENNQELKKEKNFYRNLHTRILLGENLIKKKLAILQQESKEIHADWAIIQQRLVELNLSGKDEQEKTSNLEAQENQVSEAARELGLATAEEDSILQNELPCQEAPAEHHPQHPSSSSDESSSDESSYSTCPEWE", "length": 267 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A0G2JGR8-1", "protein_name": "Predicted gene, 21680", "gene_name": "Gm21680", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRANVDGRETREGRKDADLPSESNEGRRRWTWRMWMAHRQTTSPVPVTSKKQFEKEEKELIKKIQLTTKEINELRDRLIYVTKGSMNKRPYHRQTRHYKELKLKEKEIMTYLHELEMKNMEARENKQELKKEKNFYRNLHTRILLEENLIKKKLVILQQESKEVHADWATIHQSLVELNLSGKDEQEKTSNLETQEHQVSEAARELVLATAEEDSILQNELPCQEAPAEHHPQHPPSSSDESSSDESSYSTCPEWE", "length": 267 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A0G2JMD5-1", "protein_name": "PRAME family member 33", "gene_name": "PRAMEF33", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSLQAPSRLLELAGQSLLRNQFLTIFTLDELPREVFPLMFMEAFSMRRFEALKLMVQAWPFLRLPLGSLMKTPHLETLQAVLRGLDTLVAQKVRPRRWKLQVLDLQDVDENFWTIWSGARVLSCSPEAMSKRQTVEDCPRMGEHQPLKVFIDLCLKESTLDECLSYLFGWIHYRRGLVHLCCSKVQNYSMPTSSFRNLLERIYPDSIQELEVWKKCSLNKTGKFAPYLSQMSNLRELFLAFGYERELYVSVQWPCIPDLDSPFLCLYYPQMLYIKKISNIKEHLEHLLRYLKNPLGAFIFSDAYLADRDMECLSQYPSLSQLKELRLIHILMWTTNLQPLGALLEKVAATLKTLVLKDCRIQDPQLRVLLPALSHCSQLTTFNFHGNETSMNALKDLLRHTRGLSKLGLELYPAPLESLDYKGHVNWEILTPIRAELMRTLREVRQPKRIFFGPVPCPTCGSWPSEKVDFHLCS", "length": 474 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A0G2JNH3-1", "protein_name": "Olfactory receptor", "gene_name": "LOC124905359", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKIANNTVVTEFILLGLTQSQDIQLLVFVLILIFYLIILPGNFLIIFTIRSDPGLTAPLYFFLGNLAFLDASYSFIVAPRMLVDFFSEKKVISYRGCITQLFFLHFLGGGEGLLLVVMAFDRYIAICRPLHCSTVMNPRACYAMMLALWLGGFVHSIIQVVLILRLPFCGPNQLDNFFCDVRQVIKLACTDMFVVELLMVFNSGLMTLLCFLGLLASYAVILCHVRRAASEGKNKAMSMCTTRVIIILLMFGPAIFIYMCPFRALPADKMVSLFHTVIFPLMNPMIYTLRNQEVKTSMKRLLSRHVVCQVDFIIRN", "length": 316 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A0G2JTV6-1", "protein_name": "RIKEN cDNA 4931429L15 gene like", "gene_name": "4931429L15Rikl", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQFNPFSQDTWRHGHRRAYSNISERLSCLTLQEPSVSHLYQIFSPGDRRSYLLDDSLSNSIQRESLAVPMGLEDSGSRGQQKQQQPGAVLEDLEEQEIAPTDVKYRLQLLDEAPLRSKSSSVQSQGHKPGWIPSSKTHREWFKPWKMDMTYPENERSHSGHTQGRRMTPRAQWRHVEYDSQDQDTQSPVWSQALFPGLDKSSQGVIQCTQHVSREREMVSGWSMTHAPQEMGQAKQGPAFLKTKGTAKFNVATTARMSCLPPLKLLEKKVKSRCPPNTPGIFQDWRAQPQGLYGSDERLLAPFEDQVNTRVTYMPLFTEKVKFVSPKTAVSNPKQTHSQLSRTNQPAFPGQFRNWTSGREHLEKGLPE", "length": 368 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2JVP7-1", "protein_name": "40S ribosomal protein S26", "gene_name": "Rps26-ps4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTKKRRNNGRTKKGRGHVQPIGCANCSWCVPKDKAIKKFVIWNIVETAAVRDISEARIFDAYVLPKLYVKLHYCVSLAIHSKVIRNQSHEARKDRTSPPRFRPAGAAPRPPPKPM", "length": 115 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2JW93-1", "protein_name": "High mobility group protein B4", "gene_name": "Hmgb4l4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGKDSKVRPKVNVSPYVHFMMDFRNQTREQQPNTYYDFTEFSRKCSEKWKTISKKEKKKYEALAKRDKDRYQREMRNYSGPRRERRRRDPDAPRKPPSSFLLFSQDHFDEIKEQHPNWTVAQVAKAAGRMWARCSEADKIPYEERAAVLRAKYLEEREAYYHQCQRGE", "length": 168 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2JW96-1", "protein_name": "Zinc finger protein 94 like 1", "gene_name": "Zfp94l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLPRGSCDVMLESLRNVASLGHRIGTPDGLLRLKREDMFWLLTVARWSSGSMGDKNLEDMEFLEEVGLRHLPHEELFCSQIWQRITRELTKVRDCRVRVGENGSPMKRDNREDEYSKHSSQNSVFQVHHRECHEEEANERDFGCSHHLRTSTGEKSYKCEKCHNASHWFSSLQSHQGVCDRPRWNKSVSQFKIFRQWPLFHYQQSMPNGENAQEYEACGNAGKNSSGQTALFVHTAEEPYSCEECGARFSQSSYLQVHQRVHTGEKPYKCEECGKGFGWLSQLHAHHQSHTGEKPYTCDACGKGFSYSSHLNIHCRIHTGEKPYQCEECGKGFSQASNLLAHQRGHTGEKPYQCDACGKGFSRISDFNIHIRVHTGEKPYKCEECGKGFSQASNLLAHQRGHTGEKPYKCNTCGKSFRRSSDLNVHCRIHTGEKPYRCEKCDKVFSQFSSLQVHQRVHTGEKPYQCSECGKGFSVGSQLQAHQRCHTGERPYQCEECGKGFCRASNFLAHHGVHTGEKPYRCDMCGKHFRQRSYLQAHHRVHTGEKQFRCEECGKGFSWSSYLQAHQRVHMGEKPYKCEECGKGFSWSSSLLTHQRVHAEDEGQKDLSSSGGSYRK", "length": 616 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2JYP5-1", "protein_name": "Olfactory receptor", "gene_name": "Or8g52b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPEGNHSRVTEFILTGLTDKPELQLPLFLLFLGIYLLTVLGNLGMIILILLSSHLQTPMYFFLSGLSFIDLGYSTVIIPKMLVNFVTEKNVISYPGCMTQLYCFIAFVLCECYMLSAMAFDRYVAICNPLRYNVTMSYQVCFWMIGGVYSIGFIEATIHTVCMLQVFFCKANVVNHFFCDLLPLFQLACSSTFVNETVLLCLSTLNFCVPTLTILSSYSFIIARIIRIKSTESRFKAFSTCSSHFSSVAVFFGSLGFVYFQPSSVSSKDQGKVSSVFYTIIVPMLNPLIYSLRNKDVKLALNKLFQKKIFHM", "length": 312 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2K381-1", "protein_name": "Killer cell lectin-like receptor, subfamily A, member 4", "gene_name": "Klra4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSEQEVTYSTLRFHNSSGLQNQVKTNETQGPRETGHRGCSVSWHLIMIPLGILCSILLVTVAVLVTHIFQYSQEKHELQEALNKLHHNYSTMQNESYLNEEMLGNKSSECDAYKSVLDSLNRQQNTCLRLTNIVLDCLQHKGRQVNVHLFCCGIKCYYFIMDKKQWKECEQACQGCKLSLLTIDDEDELKFLQLQVTPDSYWIGLSYDNKKHDSAWIDNNPSKL", "length": 224 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2K3S0-1", "protein_name": "Olfactory receptor", "gene_name": "Or4c109", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MYNQSFVNEFILLGLSQNPQIKKISFVIFLLVYIATLVGNMMIVVTIAYSPALLGSPMYFFLAVLSFLDACVSSVVTPKMIVDMVYERKSISFECCMTQVFAVHFLTAVEVIVLAAMAYDRYVAICKPLHYSSIMNRRLCGTLVGVAWAGGFLHSIIQIAFTLPLPFCGPNVIDHFICDLFPLLKLACTDTHIFIILVFANSGSICIIIFSFLLISYGVILFALRAHSSEGRRKALSTCGSHITVVVFFFVPCILIYARPTSAFSFEKNVFVFTDVLTPLLNPMVYTFRNKEMINAIRKMWKRLIVVSDKY", "length": 311 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2K622-1", "protein_name": "Histone RNA hairpin-binding protein", "gene_name": "Slbpl", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSLSSRMEMVSVGVTTEPCHARWEVETDEVVLRRRQKQIDYGKCTPGYQSFLQQVPRAQRQPGFHPQTPNKNRRYSRRSWDAQIRQWRRALHTWDPPSQPLHDRQAEGKAAGNFLRPVDTAPLDDLLDNWPQDPESSENWDRGEKEAQFAYLKVPASCPPQLKDELLHH", "length": 169 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2K698-1", "protein_name": "Lamin tail domain containing 1", "gene_name": "Lmntd1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSHLASSHRVQKSSLARPERRAKSPSYTDISFWVPVMHRVGSQYQFESVCEQSSGYPGMPAQQVTPVPSQRGGILRKEEKTGTITPSKQHSSVHFFPKVMDSSSTLHLLSGSFSHEASANFHQIPSAQDSLSPGGLLTSKSNVPSCSRKDSIPGKQSTHQAASPGTSLMTLKKQPKPSSDLDTYVLGDGEDYFLSLFGDSKKLTSHTSQAEDVSKHLSVILEEVGQFVSSSLGDIKIAEVNVKGFFVRLVNSSNEKEVEIGNYILQQNVNGQAVSLYRFPHNITMQASGTVTVWAAASEAKPQQPTDFVWEEQSRFRSSPDCTTILCKPSGEAIAWYTPIHWKQAWEKLETDIEFERCSVVIPSLKSHIFGRTTSSVSSINKEKQEPTQKTPPQVCSVLLREKEILLTVLPNKSPWCRSPDTPPHPYSSLIEWHDSDFPGSSLGTQPKPQSTKPKPDPGTKEKKSTR", "length": 467 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2K6E6-1", "protein_name": "Rho GTPase-activating protein 20-like", "gene_name": "LOC120093152", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGEIHRTLLCQGPVELTSGRKRNKRYLSLFDDVLVVSTNLTKKKFKIKCIIPLNYLWVVDDEELVRANKTCTCKTIFFYWATGNALATFRSEEQKVQWYTFLTSRSISEAKKGIKKTFPLHIFPEDIQTCDSSLCVTATNMDTVNDIMEKLLPMIRVHKIEDYQLWFSPGHKEAPRALQGHEYPYDIIMNNVQNNLSKSNSKIFTAFPPLPGLFMENQSWDTGGQFILKPRDSAGSQQQDAKERRRKSCMTSCFHGGCVPHHDQECSDPRDDKRGKLFGQDLSSICQDGKLPTIILDMLSRIKDKGPTTDDIFLITPNGSLCKTIKEKLDNGENVDIYQQPVHVVAWILKEFLQSIKGSLLTSKLYDQWLIVPEKVNDKEKLAAVKSLLEKLPKPNADLLRQLFRILHQIKTKSSVNNMSSFRLSLETAPCILWLPSYRNNILTNDIAKKISLVTFMIDNSPELFGEDIVAVWYETSLYHPPGLKYPCSQNTPSSNGIMEETEHGLSSCPGERTCTPDFDELPRSGAVASIPYEGILASEKGEGNESTTQPEPVQNSPTPQTKKELGNCSPNILKDVNVPAVILDMLSVIAEKGQCSDDIFRMQAEKSHWSLKEKVNTGKHVNLKEESVLTVASVVKDFIKNIEGSLLSCDLYENWLSIPDEGPLLGKIASIQNILLKMPKPNYVLLKQLICVLQKIKAASTNQLDTFDLSVRIAPHVLWNPTCKMFYGRDLSKKLSIIQFMIDNCQELFGENDNIFCEDNQKSYDINLSSDTLNTSGKATLMIETIDDHDVKTSKANTKELEMSSAVPHEGGPTAGHNGTTSKYNVPQEIILHD", "length": 835 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2K6V9-1", "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "Smokwl2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDITSIKKTLGSQYRVVFFLGQGSYGRVRLAWHRRTQALVAIKTVEISKDTIRGILSEMTTLESLNHPNIISLYEVLITGTGVHFILQYAPGGNLGKLISEEGPLPEEKAKKMFGQVVSAIRYCHSLDIVHRDIKPQNILIDGEGNIKLIDFGQAIKCKPGTLLSRHCGTRDFNAPELVLREPYDGKSSDVWSLGVVLYFFTTGYLPFRGKTINDVEERITTGTYTIPTHLSGQLENLIHQILRVSPDMRPSVEEIENHPWIKKCEFKILPKTDPDYKIIEMLCAMGYKAKDILESLQKKRYDEPMGAYLSLKDHVSKGFDVGYITPAKPGDPCPPPPPSPAHPSVFGLPLRRRASEPIFGLHHRPPSREQNPLDLILSGLKMSRCVSMPPIAVYYPKKERSTSTRALHSTPVACPCVSNNMSEVEIILPPKQDIEMNTSSPPQRMGWFKRLRKGIRDCFSRLCCLPRAPKKKTQHRSSKRVAPLKKAASSTI", "length": 493 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2K894-1", "protein_name": "Olfactory receptor", "gene_name": "Or4x6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAHLLNVTEFIFLGLSPNKEGQRVCFVLFLLLYMAIVLGNLLMVVTVAASRNLGSPMYFFLSFLSFVEICYSSTTAPKLIFDLLAEKKSISVWGCMTQLFFMHFFGGTEIFLLTMMAYDRYVAICKPLHYTSIMNQQVCAVLVGSAWIGGFVHSFSQILLILPLSFCGPNVIDHYFCDLLPVLKLACSDTFLIGLLIVVNGGTLSVISFVVLLASYLVILFHLRTQSAEGRRKALSTCGSHVTVVILFFGPCVFIYSRPSDTLPVDKMIAVFYTVITPLLNPLIYSLRNAEVKKAMKNLWFRIMKADEK", "length": 309 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2KB39-1", "protein_name": "Myb/SANT DNA binding domain containing 5 like 1", "gene_name": "Msantd5l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQREANQGESLENTEESNVGKSVKEEEQRPSGRSRSSWTDSEIRVFLQEWEVVEQEMGQPGRKLHKKTKSLCQRLYQQGLKKSWKSCFHLLLSLQDLHRTLCNERPGIEPLFSPYSEALYRILGSTPHESWFPGPLYDEADDSMLPVYPQPPMYQPSDYGITVPSAQLQGNPVPMMCQEDSPFPTWEPWNPSYPLSVPHLLPGFAPGDPSLQQPWSMCDLHQDPQ", "length": 225 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2KBC9-1", "protein_name": "Leukocyte immunoglobulin-like receptor subfamily B member 3-like", "gene_name": "Lilrb3l", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTFTFTALLCLGLTLRLWIPVLTGSLPKPILRVQPDSVVSMGTKVTFVCEETIGVKESHLYRNGNLQRTVLKNHQKPTNKTEFSFSNVDQQMQQYQCSYRTQTKSSDYSEPLELVVTGAYSKPSLSAQTNPVVTSGGYVTLKCEPSQDNHTLILTVEGSQKHSWRKDPECNRYTEKCHALFYVGPLTSNQRWIFRCYSYEKHTPQVWSAPSEPVELLVSGKLQKTTIKAEPGSVIRSGRAMTIWCQGDLDAEIYFLHKEGSHNTQSTQTLQQPGNKAKFLIPSVTQRHAGQYRCYCYSSAGWSEPSDTLELVVTGIYYYGVKLSGLPSPVVPEGGNVTLHCTSHSNYDKFILTKEDQKFTSSLDAEYIPSTGQHQALFVMGPMTPNYSGTFRCYGYYKHTPQLWSVPSELLKIFISGPSRKPSLLSHQGHILEPGMSLTLQCYSDTKYDKFALYKEGGTDIIESFSQWTKAGLSMTNFTLSVMPNSTVHSGENVTLMCWSTYSVDTFILSKEGSGQPPLRLKSKIQDQQYQSEFSMSGVTSKLSGTYRCYGSHDSSLYLKALIGVSVAFLLFLFILIFILLRRRHQEKFRKDDEDAQKGKELQLSTGAAEPVTRDRGHQKRSNPAAATQEESLYASVEDMETKDGVELDTWKPPEGDPQGETYAQVEPSRLRRAGAISPVVSREQLNTKYEQAEEGQEVDSQATESEEPQDVTYAQLCSRTLRQGTAAPPLSQAGEAPEEPSVYAALATARPGAVPKNKKQ", "length": 761 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2KIH5-1", "protein_name": "Major histocompatibility complex class I LLA precursor", "gene_name": "mhc1lla", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTGKVLFVLFLLSAPTTVLTDSHSLWLLGTYIKGETQFPKLSFTVMLDDLRVGFYNSETKEFIPRDNTTNEDEAVSDVLTVIQNTLEPFMMSTLTFKNGTESPQLFQITWHCELLDNDKPGQIIFKIAFSGSTTDEVSFYNDNFTCQCQNNMATVPLESFQMHYETVCYPNCIATIRDYLKKRQTQVNGKVQPKVRLIKKVHPKSGGFRLSCLATEFYPHSINLTLLRDGQPVSDHEVTGGNLLPNGDGTYQMRKSLEIRADEREKHKYTCSVSHLSLDKILDIDFEFDPSFLIKIVIPVVVLLSLMLVLTAVLIHKCKNKRAESKETITTASTPEPTEMSETLRK", "length": 346 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A0R4IEQ0-1", "protein_name": "Guanine nucleotide-binding protein subunit alpha", "gene_name": "gna11a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTLESMMACCMSEEAKESKRINAEIDKQLRRDKRDARRELKLLLLGESGKSTFIKQMRIIHGTGYTDEDKRGYTKLVYQNIFTSMQAMIRATEHLKIPFRFEDNKKNALLVREVDVEKVCSFEQPYVAAINKLWMDPGIQEAYDRRREYQLSDSTKYYLNDLERISSRGYMPTQQDVLRVRVPTTGIIEYPFDLENIIFSYLSDLERISDPSYLPTQQDVLRVRIPTTGIIEYPFDLQSIIFRMVDVGGQRSERRKWIHCFENVTSIMFLVALSEYDQVLVESDNENRMEESKALFRTIITYPWFQNSSVILFLNKKDLLEEKILCSHLVDYFPEFDGPQNDAQSAREFILKMFVDLNPDSDKIIYSHFTCATDTENIRFVFAAVKDTILQHNLKEYNLV", "length": 400 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A0R4ILG2-1", "protein_name": "FXYD domain-containing ion transport regulator", "gene_name": "fxyd2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MGVESPEHSDADFTYDYELIRRGGLIFAAVLFCLGMVIIFSKKLRCGKSSATHEDNGDL", "length": 59 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A0R4IU63-1", "protein_name": "Metabotropic glutamate receptor 5", "gene_name": "grm1b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MRMLILRMNFFIVFLLFCTRLHLSTERSAVSRAASRSVARMDGDIIIGALFSVHHQPSAEKVAERKCGEIREQYGIQRVEAMFYTLDRINSDPYLLPNITLGCEIRDSCWHSSVALEQSIEFIRDSLISIRDEREGPKWCVEGNPSAQPPATKKPIAGVIGPGSSSVAIQVQNLLQLFNIPQIAYSATSIDLSDKTLYKYFLRVVPSDTLQARALLDIVKRYNWTYVSAVHTEGNYGESGMEAFKELASQEGLCIAHSDKIYSNAGEKHFDRLLRKLRERLPKARVVVCFCEGMTVRGLLMAMRRLGVAGEFLLIGSDGWADRDEVVEGYEEEAVGGITVKLQTEEVTSFNDYFLKLRLATNNRNPWFAEFWQHRFQCRLAGHPQENTNYRKNCSGYESLEDNYVQDSKMGFVINAIYAMAHGLHDMHEHLCPGHVGLCEEMDPIDGSKLLDFLLKTSFAGVSGEDVWFDENGDSPGRYDIMNLQYVEPGVFDYINVGSWHEGILSIDDYMIQMNRSEMVRSVCSEPCSKGEIKVIRKGEVSCCWICTPCKDNEYVQDEFTCKACELGWWPDEELQVCEPLPLRYLEWSHPESIAAVVFSCLGILVTSFVTLVFILYRDTPVVKSSSRELCYIILAGIFLGYICPFTLIARPSIASCYLQRLLVGLSASMCYSALVTKTNRIARILAGSKKKICTRKPRFMSAWAQVVIAFILISMQLTLEVTLIILEPPEPIKSYPSIREVFLICNTSNMGMVAPLGYNGLLILSCTYYAFKTRNVPANFNEAKYIAFTMYTTCIIWLAFVPIYFGSNYKIITTSFSVSLSVTVALGCMFTPKMYIIIAKPERNVRSAFTTSDVVRMHVGDGKIACRSNSLLNMFKRKKNASGNANSNGKSVSWSEPGSRHPPKGEHMWHRLSVHVKKQEAGSNQTAIIKPLTNTYNNPGMEFSDLSTKTLYNVAEEDEIDPIRYNPSNSPHLMAPVSKPMKEVGANLTFYTPEQHVPQQNSVLPQHAMIEHFQDDVVKYNSNMADLDEIISLPEPTDGIILALQPQVLHPHPILPMNVYQDEPSSPLEEVENEQFGLLHGYMYDNAQIHDEEELVQIKMAMEDSMALMPPSPFRDSLGSGSPVRNSPVSESVLCTPPSVTYASVILRDYKQSSSTL", "length": 1158 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A0R4IUN8-1", "protein_name": "Trypsin inhibitor ClTI-1-like precursor", "gene_name": "spink2.9", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLAQIVLLLCLSVMATAADKCPSVPNCSRYHPHACTMEYWPVCGSDGNTYGNECELCATIFEEKLNIILISKKGEC", "length": 76 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A0R4J2B9-1", "protein_name": "BTB domain containing 35, family member 23", "gene_name": "Btbd35f23", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEGIAGASYIPVSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFTNILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQKCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICNLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYNQEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A140T8Q5-1", "protein_name": "BTB domain containing 35, family member 21", "gene_name": "Btbd35f21", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDMKLMYLLALSSDLLVMQKEIDVYTTLKIWMILYLNPCWNGTMKQLLQHANNWLSTHMAYIDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYNEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1B0GQX3-1", "protein_name": "Cortexin domain containing 2", "gene_name": "Ctxnd2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MCVLMEDSSMSNGIDVDKGFAIAFVVLVFVFLIVMVFRCVKLVKNPYEVSSTTADLPLN", "length": 59 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1B0GRH6-1", "protein_name": "Zinc finger and SCAN domain containing 4, pseudogene 3", "gene_name": "Zscan4-ps3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASQQAPAKDLQTNNLEFTPTDSSGVQWAEDISNSPSAQLNFSPSNNGCWATQELQSLWKMFNSWLQPEKQTKEQMISQLVLEQFLLTGHCKDKYALTEKWKASGSDMRRFMESLTDECLKPPVMVHVSMQGQEALFSENMPLKEVIKLLKQQQYATRPTPDNEQMPVDTTQDRLLATGQENSENECNNSCNATEANVGESCSGNEMDSLLIIQKEQHPEHEEGNVVRQFPHGARRASQGTPSHHVDIQSPPTTADVTMEEQPKDLSRENISEDKNNCYNTSRNAATQVYSGDNIPRNKSDSLFINKRIYHPEPEVGDIPYGFPQDSTRASQGTSTCLQESLGECFSEKDPREVPGLQSRQEQLISDPVLLGKNHEANLPCKSHQKRFCRDAKLYKCEECSRMFKHARSLSSHQKTHLNKKSELLCVTCQKMFKRVSDRRTHEIIHMPEKPFKCSTCEKSFSHKTNLKSHEMIHTGEMPYVCSLCSRRFRQSSTYHRHLRNYHRSD", "length": 506 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1B0GS00-1", "protein_name": "Predicted gene, 36210", "gene_name": "Gm36210", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MHPGSPAAPGVSEPGPRELCAFVSGASAHMLRALQPRRIRPSKRRPNHRRFLHNQICREFAKIEAATQHLALTILSQKAPAQRPPFRRPPPPPPSPFLGVACAEAPMEAPHGSPSLSPVALDTSTLDLFDDILLTPTPRPLVTPDSFCQTLPAGNPQVASDVISHALGPGDQGQPTPIQAPRFSNLLLPPQKAQGGSLEPAALGCGWVDSWEAPYACDPQGVLDSWGAL", "length": 229 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1B0GSB3-1", "protein_name": "Family with sequence similarity 236, member D", "gene_name": "Fam236d", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MIVMHLVGHPQLTGTEGVATEGVATAHTMLTSRGPRDTREPAPPTRSWRSRFQRALARVSKFFRRGRRTARG", "length": 72 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1B0GSI2-1", "protein_name": "Family with sequence similarity 236, member C", "gene_name": "Fam236c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MIVMHLVGHPQLTGTEGVATAHTKENSSRGPRETREPAPCTRSWRSRFQRAVARVSKFFRRRRRST", "length": 66 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1C7CYU6-1", "protein_name": "Zinc finger and SCAN domain containing 4, pseudogene 2", "gene_name": "Zscan4-ps2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASQQAPAKDLQTNNLEFTPTDSSGVQWAEDISNSPSAQLNFSPSNNGCWATQELQSLWKMFNSWLQPEKQTKEQMISQLVLEQFLLTGHCKDKYALTEKWKASGSDMRRFMESLTDECLKPPVMVHVSMQGQEALFSENMPLKEVIKLLKQQQYATRPTPDNEQMPVDTTQDRLLATGQENSENECNNSCNATEGNVGESCSGNEMDSLLIIQKEQHPEHEEGNVVCQFPHGARRASQGTPSHHVDFPSVPTTADVPMEEQPKDLSRENISEDKNNCYNTSRNAATQVYSGDNIPRNKSDSLFINKRIYHPEPEVGDIPYGVPQDSTRASQGTSTCLQESLGECFSEKDPREVPGLQSRQEQLISDPVLLGKNHEANLPCESHQKRFCRDAKLYKCEECSRMFKHARSLSSHQRTHLNKKSELLCVTCQKMFKRVSDRRTHEIIHMPEKPFKCSTCEKSFSHKTNLKSHEMIHTGEMPYVCSLCSRRFRQSSTYHRHLRNYHRSD", "length": 506 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1C7CYV3-1", "protein_name": "Zinc finger and SCAN domain containing 4, pseudogene 1", "gene_name": "Zscan4-ps1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASQQAPAKDLQTNNLEFTPTDSSGVQWAEDISNSPSAQLNFSPSNNGCWAIQELQSLWKMFNSWLQPEKQTKEQMISQLVLEQFLLTGHCKDKYTLTEKWKASGSDMRRFMESLTDECLKPPVMVHVSMQGQEALFSENMPLKEVIKLLKQQQSATRPTPDNEQMPVDTTQDRLLATGQENSENECNTSCNATEGNVGERCGGNEMDSLLIIQKEQHPEHEEGNVVCRFPHGARRASQGNSSHHVDFRSALTPADVPMEEQPKDLSRENISEDKNNCYNTSRNAATQVYSSDNIPRKKTDSLSINKRIYHPEPEVGDIPYGVPHDSTRASQGTSTCLQESLGECFSEKDPREVPGLESRQEEPISDPVLLGKNHEANLPCESHHKRFRRDAKLYKCEECSRMFKHARSLSSHQRTHLNKKSELLCFTCQKMFKRVSDRRTHEIIHMPEKPFKCSTCEKSFSHKTNLKSHEMIHTGEMPYVCSLCSRRFRQSSTYHRHLRNYHRSD", "length": 506 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1D5P3Y4-1", "protein_name": "Large ribosomal subunit protein uL24m", "gene_name": "MRPL24", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MRLSALLRLAAPPKLPKGYRHGTWRPGTAAERLRNPPGQRRKKIFVEPISREDWKVFRGDTVQVLTGKDAGKQGMVTQVVRARNWVVVEGLNTHYRYVNRDAKYSSTYIASEAPLLLNQISLVDPEDRKPTEVDWRYTEEGERVRVSLRTGRIIPLPLWQRRDGIVPEQWIDGPKDTSVDDALDKTYTPSLKTFEEEIMDAMGIVETRRAKKSYWY", "length": 216 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A1D5PNZ8-1", "protein_name": "ODF3A protein", "gene_name": "LOC124417034", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MPASMDGAWVGTWRPHRPRGLISAQFPSPGPQYSIPGTTGYVGHSPTKARAPAYTFRGTKPPAAGSCGPGPCYFVEPAITRNGKYVAPGAQLRGRPATKTTVTPGPSDYRTEAANRHVFKCPPVQSMAFRREPLRTDHPPGPGTYTLPRLMGPNTVYTSASPCYSVRGRSQRGRFDEDLAKTPGPAALPKVPVDAYKTRAPAYTMAARPKAGEGKAAKPGPADYSVGRVTLIKPQAPASTFGIRHSLYTTPLIVE", "length": 255 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A1D5RLF0-1", "protein_name": "F-box and WD-40 domain protein 27", "gene_name": "Fbxw27", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "METHLPSLPLMKIFSYLDAYSLLQVAQVNKNWNALASSDVLWRKLCQKRWLFCDMVTLQLQDKETWKQFFVYRTWQEHSKTRANPRDFTYKEIPLQYGPCGYACYISGCGITRKGQDKSVVCMVNSKNTISTWDVHKSVITWVSPEQPASIKLLTTLPEMHIAVTVDIQSTIKLWDCHNREALATNILESPCKSLKAVITKDDPIVLVSDILGNLYIFRIPDLHLISTVNVLPCDIDEIYCSPQKKWVLLSKKQPYILPKVFYMSSLLRTSEFSAPVSTLLEISLCQEAFWTPRREDRLTLMSRSGCSKITKFETYDMKLEEFGNKIIVKGNSIAGFLLPYYTESLNWFGVSDKDTIVCSTEFSLLLFTNNGHRLQTFQYFSETIVRLSVDPVHVIVTCNDGSLDVYAWEERSLLLRKCYRLKNRRHLSPRGFINKTLCDDVSIIQLMIDGHDTWFLMAYALNICS", "length": 466 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1P8ASP4-1", "protein_name": "Serine/threonine-protein kinase PRP4 homolog", "gene_name": "PRP4KB", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MVSDKHVESNHRKHRRSFSPSDEVFKSPKRHKSRHHHRRHGHRHHRDEEVQYNDDENVNGGDLDMEEGEILGKEGIGETLKKKLESVDEFGDIKSGQFRENNLAFNGDDGFPLICKSWIRVYNYLSYKCHGRNQRRERECEKRKEIEPDRERRKERGSVDRDSRGDREKDYLRDRDNDRGRSRDKARYSSRERGRENERERRSEKDRDKGREFQSDREKHKSLDDGYGEVRHKHSGHSRHDAEDDLELRSPTSVNGHDPNSGDVKETRGNVERTRIDNDDKGDVVVWEVEQEDEELNLIEESRRRTQAIMEKYKKKLEQQNGFSSHDLELANIPKQSSTVADVLGSGTLGPVTSAVNQAKAGLDIDAVDGEVAKLSSAVGESPAQLVISDSDRTLASTGLGEGSPKDKISDDMFTDDIFGESPADSQKMVCTLTQIIDLVFIEFSNSGFICFVFPVHHLTRYSRNGLPFVHYIFVGYLRGKGNGIPIVRSGLDDNWDDAEGYYSYQLGELLDDRYEIMATHGKGVFSTVVRAKDTKAELGEPEEVAIKIIRNNETMHKAGQTEIQILKKLAGSDPENKRHCVRFLSTFKYRNHLCLVFESLHLNLREIVKKYGRNIGIQLSGVRVYATQLFISLKHLKNCGVLHCDIKPDNMLVNEGRNTLKLCDFGSAMFAGTNEVTPYLVSRFYRAPEIILGLPYDHPLDIWSVGCCLYELFSGKIMFPGSTNNEMLRLHMELKGAFPKKMLRKGAFIDQHFDKDLCFYATEEDSVTRKTTKRMMVNIKPKEFGSVIKQRYKDEDSKLLVHFRDLLDRIFILDPQKRITVSQALAHPFITGK", "length": 834 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "A0A1P8BFV1-1", "protein_name": "Bax inhibitor-1 family protein", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MDGLKDFSRISPAIQSHLMRVYFSLFCILAASAFGAYLHMRLNIGGTITKLGWVLSLLEHVVSCPPYKHKIRFSLLLLFGVLHGASVGPCIKSTIDIDSSILITAFLGTAVIFFCFSAVAMLARRREYIYLGGLLSSGFSLLTWLKNSDQFASATVEIQMYLGLLLFVGCIVVNTQEIIEKAHCGDMDYAVHSLILYIGFVRVFLQILSIMWNTSADRIRRNNEET", "length": 226 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "A0A1W2P6Q8-1", "protein_name": "Cell division cycle 5-like protein", "gene_name": "Cdc5lrt6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPRIMIKGGVWRNTEDEILKAAVMKYGKNQWSRIASLLHRKSAKQCKARWYEWLDPSIKKTEWSREEEEKLLHLAKLMPTQWRTIAPIIGRTAAQCLEHYEFLLDRTAQRDNEEETTDDPRKLKPGEIDPNPETKPARPDPIDMDEDELEMLSEARARLANTQGKKAKRKAREKQLEEARRLAALQKRRELRAAGIEIQKKRKRKRGVDYNAEIPFEKKPALGFYDTSEENYQALDADFRKLRQQDLDGELRSEKEGRDRKTDKQRLKRKKESDLPSAILQTSGVSELTKKRSKLVLPAPQISDAELQEVVKVGQASEVARQTAEESGITNSASSTLLSEYNVTNNSIALRTPRTPAPQDRILQEAQNLMALTNVDTPLKGGLNTPLHESDFSGVTPQRQVVQTPNTVLSTPLRTPSNGAEGLTPRSGTTPKPVTNATPGRTPLRDKLNINPEDGMADYSDPSYVKQMERESREHLRLGFLGLPAPKNDFEIVLPENAEKELEEREIDDTYIEDAADVDARKQAIRDAERVKEVKRMHKAVQKDLPRPSEVNETILRPFNVEPPLTDLQKSEELIKKEMITMLHYDLLHHPYEPSGNKKGKNVGLATNDSEHITYLEHSPYEKFSKEDLKKAQGALVQEMEVVKQGMSHGELSSEAYNQVWEECYSQVLSLIAQSRYTRANLASKKDRIESLEKRLEINRGHMTTEAKRAAKMEKKMKILLGGYQSRAMGLMKQLNDLWDQIEQAHLELRTFEELKKREDSAIPRRLECLKEDVQLQQEREKELQQRYADLLMEKETLQAKF", "length": 802 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1W2P7S8-1", "protein_name": "Cell division cycle 5-like protein", "gene_name": "Cdc5lrt1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPRIMIKGGVWRNTEDEILKAAVMKYGKNQWSRIASLLHRKSAKQCKARWYEWLDPSIKKTEWSREEEEKLLHLAKLMPTQWRTIAPIIGRTAAQCLEHYEFLLDKTAQRDNEEETTDDPRKLKPGEIDPNPETKPARPDPIDMDEDELEMLSEARARLANTQGKKAKRKAREKQLEEARRLAALQKRRELRAAGIEIQKKRKRKRGVDYNAEIPFEKKPALGFYDTSEENYQALDADFRKMRQQDLDGELRSEKEGRDRKTDKQRLKRKKESDLPSAILQTSGVSEFTKKRSKLVLPAPQISDAELQEVVKVGQASEVARQTAEESGITNSASSTLLSEYNVTNNSIALRTPRTPAPQDRILQEAQNLMALTNVDTPLIGGLNTPLHESDFSGVTPQQQVVQTPNTVLSTPLRTPSNGAEGLTPRSGTTPKPVTNATPGRTPLRDKLHINPEDGMADHSDPSYVKQMERESREHLRLGFLGLPAPKNDFEIVLPENAEKELEEREIDDTYIEDAADVDARKQATRDAERVKEMKRMHKAVQKDLPRPSEVNETILRPFDVEPPLTDLQKSEELIKKEMITMLHYDLLHHPYEPSGNKKGKNVGFATNDSEHITYLEHSPYEKFSKEDLKKAQDALVQEMEVVKQGMSHGELSSEAYNQVWEECYSQVLYLPAQSCYTRANLASKKDRIESLEKRLEINRGHMTTEAKRAAKMEKKMKILLGGYQSRAMGLMKQLNDLWDQIEQAHLELRTFEELKKHEDSAIPRRLECLEEDVQRQQEREKELQQRYADLLMEKETLQAKF", "length": 802 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1W2P7Z8-1", "protein_name": "Cell division cycle 5-like protein", "gene_name": "Cdc5lrt7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPRIMIKGGVWRNTEDEILKAAVMKYGKNQWSRIASLLHRKSAKQCKARWYEWLDPSIKKTEWSREEEEKLLHLAKLMPTQWRTIAPIIGRTAAQCLEHYEFLLDRTAQRDNEEETTDDPRKLKPGEIDPNPETKPARPDPIDMDEDELEMLSEARARLANTQGKKAKRKAREKQLEEARRLAALQKRRELRAAGIEIQKKRKRKRGVDYNAEIPFEKKPALGFYDTSEENYQALDADFRKLRQQDLDGELRSEKEGRDRKTDKQRLKRKKESDLPSAILQTSGVSELTKKRSKLVLPAPQISDAELQEVVKVGQASEVARQTAEESGITNSASSTLLSEYNVTNNSIALRTPRTPAPQDRILQEAQNLMALTNVDTPLKGGLNTPLHESDFSGVTPQRQVVQTPNTVLSTPFRTPSNGAEGLTPRSGTTPKPVTNATPGRTPLRDKLNINPEDGMADYSDPSYVKQMERESREHLRLGFLGLPAPKNDFEIVLPENAEKELEEREIDDTYIEDAADVDARKQAIRDAERVKEVKRMHKAVQKDLPRPSEVNETILRPFNVEPPLTDLQKSEELIKKEMITMLHYDLLHHPYEPSGNKKGKNVGLATNDSEHITYLEHSPYEKFSKEDLKKAQGALVQEMEVVKQGMSHGELSSEAYNQVWEECYSQVLSLIAQSRYTRANLASKKDRIESLEKRLEINRGHMTTEAKRAAKMEKKMKILLGGYQSRAMGLMKQLNDLWDQIEQAHLELRTFEELKKREDSAIPRRLECLKEDVQLQQEREKELQQRYADLLMEKETLQAKF", "length": 802 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1W2P855-1", "protein_name": "Cell division cycle 5-like protein", "gene_name": "Cdc5lrt8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPRIMIKGGVWRNTEDEILKAAIMKYRKNQWSRIASLLHRKSAKQCKARWYEWLDPSIKKTEWSREEEEKLLHLAKLMPTQWRTIAPIIGRTAAQCLEHYEFLLDRTAQRDNEEETTDDPRKLKPGEIDPNPETKPARPDPIDMDEDELEMLSEARARLANTQGKKAKRKAREKQLEEARRLAALQKRRELRAAGIEIQKKRKRKRGVDYNAEIPFEKKPALGFYDTSEENYQALDADFRKLRQQDLDGELRSEKEGRDRKTDKQRLKRKKESDLPSAILQTSGVSELTKKRSKLVLPAPQISDAELQEVVKVGQASEVARQTAEESGITNSASSTLLSEYNVTNNSIALRTPRTPAPQDRILQEAQNLMALTNVDTPLKGGLNTPLHESDFSGVTPQRQVVQTPNTVLSTPLRTPSNGAEGLTPRSGTTPKPVTNATPGRTPLRDKLNINPEDGMADYSDPSYVKQMERESREHLRLGFLGLPAPKNDFEIVLPENAEKELEEREIDDTYIEDAADVDARKQAIRDAERVKEVKRMHKAVQKDLPRPSEVNETILRPFNVEPPLTDLQKSEELIKKEMITMLHYDLLHHPYEPSGNKKGKNVGLATNDSEHITYLEHSPYEKFSKEDLKKAQGALVQEMEVVKQGMSHGELSSEAYNQVWEECYSQVLSLIAQSRYTRANLASKKDRIESLEKRLEINRGHMTTEAKRAAKMEKKMKILLGGYQSRAMGLMKQLNDLWDQIEQAHLELRTFEELKKREDSAIPRRLECLKEDVQLQQEREKELQQRYADLLMEKETLQAKF", "length": 802 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1W2PP81-1", "protein_name": "TATA-box-binding protein-associated factor 11-like protein 5", "gene_name": "TAF11L5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "METGRQTGVSAEMLAMPRGLKGSKKDGIPEDLDGNLEAPRDQEGELRSEDVMDLTEGDSEASASAPPAAKRRKTHTKGKKESKPTVDAEEAQRMTTLLSAMSEEQLSRYEVCRRSAFPRARVAGLMRAITGSSVSENAAIAMAGIAKLFVGEVVEEALDVCEMWGETPPLQPKHLREAVRRLKPKGLFPNSNCKRIMF", "length": 198 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A1Y7VLT7-1", "protein_name": "Eukaryotic translation initiation factor 4C", "gene_name": "Eif1ad4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPKNKGKGGKNRRRGKNENESEKRELVFKEYGQEYAQVTKMLGCGWLEAMCFDGVRRLCHIRGKLRKKVWINTSDIILIGLRDYQDNKADVILKYNQDEARSLKAYGELPEHAKINEMDTFGPGDDDEIVFDDIGEDDEDIDDI", "length": 144 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1Y7VNG9-1", "protein_name": "Eukaryotic translation initiation factor 4C", "gene_name": "Eif1ad18", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPKNKGKGGKNRHRGKNENESEKRELVFKEYGQEYAQVTKMLGCLWLEAMCFDGVKRLCHIRGKLRKKVWISTSDIILIGLRDYQDNKADVILKYNPDEARSLKAYGELPEHAKINETDTFGPGDDDEIVFDDIGDDDEDIDDI", "length": 144 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A286YCH8-1", "protein_name": "Predicted gene, 47985", "gene_name": "Gm47985", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALGAELSETLVEKPEHMNLEMSILAPSKRKQLLDKKAEDKQPPESRGNNGRSSKSSPMGKDNTWPSPEAKVPSQKRSGQSWAVSSCGPHKRSSKLEDKRRNRPSRFRERGRDKPGSTHKRDSSHTKLHVKDRRSQPRSPVRTLKRSRSGDRQGAPHNSAKRHRQTSPPEASSLPTFSLLMSRVFTNVDALQVSLDDLQAPGGAFLRVPSSSTEPIVLQRAWLTWQLSHAGAALHWALHTVKSILTSQASLPRYTWPQGYSFTADPRPVPTSKIQASQLAQRPGDLASPNPSVDTRSILG", "length": 300 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A286YD13-1", "protein_name": "Predicted gene 8947", "gene_name": "Gm8947", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALGAELSETLVEKPEHMNLEMSILAPSKREQLLDKKAEDKQPPESRCNNGRSSKSSPMGKENTWPSREAKVPSQKRSGQSWAVSSCGPHKRSSKLEDKRRNRPSRFRERGRDKPGSTHKRDSSHTKLHVKDQRSQPRSPVRTLKRSRSGDRQGAPHNYAKRRRQTFPPEASCSLPTFSLLMSRVFTNVDALQVSLDDLQAPGGAFLRVPSSSTEPSVSQRAWLTWQLSHAGAALHWALHTVNSILTAQASLPRYIWPQGYSFTADPRPVPTSKIQASQLAQRPGDLASPNPSVDTRSILG", "length": 301 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A286YE43-1", "protein_name": "Predicted gene, 47996", "gene_name": "Gm47996", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALGAELSETLVEKPEHMNLEMSILAPSKRKQLLDKKAEDKQPPESRGNNGRSSKSSPMGKDNTWPSPEAKVPSQKRSGQSWAVSSCGPHKRSSKLEDKRRNRPSRFRERGRDKPGSTHKRDSSHTKLHVKDRRSQPRSPVRTLKRSRSGDRQGVPHNSAKRCRQTSPPEASSLPTFSLLMSRVFTNVDALQVSLDDLQAPGGAFLRVPSSSTEPSVSQRAWLTWQLSHAGAALHWALHTVNSILTAQASLPRYTWPQGYSFTADPRPVPTSKIQASQLAQRPGDLASPNPSVDTRSILG", "length": 300 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A286ZIN6-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "LOC110258935", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MANLTSMSGFLLMGFSDDHKLQILHALLFLVIYLLALTGHLLIITITTLDHHLHSPMYYFLKHLSLLDLCFISVTVPQSIANSLMNNGYISLGQCILQVFFFIALASSEVAILTVMSYDRYVATCQPLQYETIMDPWACRQAVIAVWVTGGLSGLTHTAINLSVPLCGDRVIHQFFCDVPQMLKLACSYEFINEIAVAAFTTSTAFFCLISILLSYTRIFSAVLRIPSAQGRTKVFSTCLPHLLVVTFFLSAAGFEFLRPPSDSQSAMDFMFSIFYTVVPLTLNPVIYSLRNKAMKAALRKVLSKEEFAQRKKYFKALFQL", "length": 321 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZIP8-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110259124", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "QEYKANGGDNTTTIIHFVLLGFSDFPHIRPALFVVFLVIYILTLTWNLCLIVLIRLDSHLHTPMYFFLSNLSFIDICYVSSTAPKMLYDFFQAKPTITVVGCAIQYFVCSTMGLSECCLMTVMAYDRYAAICNPLLYSSIMSPSLCGRMVLGSYMAGLSATLSQVCAVLQLHFCGPNVIHHFFCDMPLMLGLSCSDTFFVQVLTAIFTVFFGIINALVIMMSYVYIVISVMKITSAKGRSKAFNTCASHLTAVTLFYTSGIFVYLSSSSGGSSGLDRFAAVFYTVVIPMLNPLIYSLRNKDIKDALKRLKKRKECC", "length": 316 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZLI4-1", "protein_name": "C-C motif chemokine ligand 24", "gene_name": "CCL24", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MFSPSSLIKASGQLQCPAGNRLLAPTLSSCIAALSPELPLLLSRHGRPVTVAASLLFLGLCAYSFAPADSVTMPSSCCIYFISKKIPESRVASYQLSNSSVCPQAGVIFTTRKGQKFCGDPKQLWVQKYMKKLDAKRKKASTRIRAMGTGAPVRRGPANSTSI", "length": 163 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZSE3-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258059", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRNRTITTFILLGLTDDPKLQVLIFIFLFVAYMLSLTGNLTIITLTFVDSHLKTPMYFFLKNFSFLEISFISSCIPRYLYSIATGDKVITYNACVIQVCFTDLCGVTEFFLLAAMSYDRYVAICKPLHYVTIMSSRVCGILISSCWMAGLCVLIPPLSLGLNLKFCDSNRLDHFGCDAFPLVKISCSDTWPMEQTVIICAVLTLNMTLTCVVLSYAYIIKTIFRFPSVQQRKKAFSTCSSHMIVVSITYGTCIFIYMNPTAKGEVTIKKVVSLLIFSVSPTLNPFIYTLRNNQVKRAFKDSIKRIALLSTR", "length": 311 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZU87-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "LOC100152920", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEGENQTVLFEFIILGFSNLKELQFLLFTIFLVTYICTLGGNSFIILETMTNLHLHTPMYFFLENLAFLDICYTTTNVPQMMAHLLSEKKSISYLGCMAQLFAFIFFVGSESLLLAAMAYDHYIAICKPLRYSVIMNKVLYSQLAASCWSGGFLNSTVHTVLTFRLPFCGNNQINYFFCDIPPLLVLSCGDTSVNELALLSIGVVIGWTPFLCIVLSYLYIISTILRIRSSKGRQKAFSTCASHLTIVLLYYGSAIFTYGRPISTYSLEKDRLISVLYSIVTPMLNPIIYSWRNKDIQEAMQVMGRKWKASSSLSFDV", "length": 318 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZVC9-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258401", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGQRNSTSLHDFILLGFSDHPKLEMALSGVVATFYLITLVGNTAIILASLLDSHLHTPMYFFLRNLSFLDLCFTTSIVPQMLVNLWGPHKTISYGGCVIQLYVYMWLGSIECLLLAVMSYDRFTAICKPLHYLVIMNPHLCLKMIIMVWSISLANSVVLCTLTLNLPRCGNNLLDHFLCELPAMLKIACIDTTAVELSVFALGIAIVLTPLILILISYGYIAKAVLRMKSRAGQRKAINTCGSHLTVVSIFYGAIIYMYLQPGNNASRGQVIFLTLFYTIITPSLNPLIYTLRNKDMKEALKKLMRVDHKSTKSKRTWKS", "length": 320 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZWC4-1", "protein_name": "Zinc finger protein 16", "gene_name": "ZNF16", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MLPLSQVPAMPSLRTRPGKAEMEPSVPGPSLRTPGTQVSVSDAPAVTHPGSALHGPLSCGDTEPGATPPHHQLADWDLRTEGSQLLQKEDASEDLESQAGTSEDYVGAGSQAPERGELCADVLGSDWGVPQGERLSLCQEGGFMPAYLLPGSPLEEPEIDTEPLERNFGLIITPVASPGEPEEETPQPFDACDQSVHCGVDLAGHEGLHAAESSFICGECGESVGLHSDLLRHRLSHRGEKPHVCAECGEAFSQSASLESHQRSHEPAKPFQCSTCGKAFGRSSSLIKHHKVHTRERPHACGECGRPFSRFSNLVKHRRVHTGEKPYRCSECGKAFSQSSSLLQHRRVHTGEKPHVCPVCGKAFSYSSVLRKHQIIHTGVKPYSCSACGKAFSHSSALIQHQGVHSGDKPYECRECGKTFGRSSNLILHQRVHTGEKPYECAECGKTFSQSSTLIQHQRIHNGLKPHECDQCGKAFNRSSNLIHHQKVHTGEKPYTCVECGKGFSQSSHLIQHQIIHTGERPYKCGECGKAFSQRSVLTQHQRVHTGEKPYDCEACGKAFSQRSKLVKHQLIHARE", "length": 576 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZX75-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100156955", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "IFIMEWENQTASSDFILMGIFSHTPTHIFLFSLVLGIFTVALLANTVMVLLICLDRRLHTPMYFLLSQLSLMDLMLICTTVPKMARNYLSGRKSISVAGCETQIFFSVSLFGAECFLLAVMAYDRYAAICYPLQYPQLMNWNVCGLLAASSWILGVFDGIVDIAATLSFSYCGSREIPQFFCDITALLRLSCTDTSTFETLVFICCVVMLLFPLSLIIISYTRVIITVIRMSSGEGRHKAFTTCSSHLVVVGMYYGAAMFIYMRPTSNRSPAQDKMVSAFYTILTPMLNPLIYSLRNKDVAKAFSRCWGREI", "length": 312 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZY56-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258501", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "METDNDTQILEFLLLGFSKQPESQPIIFGLFCSMYLITVFGNLLIILAVISDYHLHIPMYFFLSKLSFVDICFTSTTIPKMLWNIQTQSKAITYEGCITQIYFLILFAVLDILLLTVMAYDRFVAICHPLHYTVIMNPRLCGLLVLVPWIMSVLNSLLQTLMMMQLSFCTNFEIPHFFCELNQMIQLACSDTFLNTIVMYFAAALLCGGPFFGILCSYSKIVSSIYRISSAQGKYKAFSTCASHLSVVSLFYCTMLGVYLSSAAAHSSHSSATASVMYTVITPMLNPFIYSLRNKDMKRALKALFVKGPM", "length": 310 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZZP6-1", "protein_name": "HSF-type DNA-binding domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MANAPSEIQGVSPKDESTGSESSITSPWCDNSITGDLDLRSQIEEKAFQALSEGSLMKEPCHTLCASEPDGDNDFPPLPFPRKLWEIVESDRFKSIWWDENGTSIVINEERFKKEVLERKAPFRIFETESMKSLVRQLNLYGFTKLRRNFQRPASLANILAEDNEVSAWNKLQFYHNPNFKRGCPHLLVRMKRRVRVKNASPVSASVLQGCSKKRSRTGGDVDNHNSDVAAETRGEDAFSASTNLNVPLIRWPSMSQRISNTTTPTRSGLSSPSSPSFRPPGQIAMAQHAIFSQLTTFHMHSQSSYSPASGHIVNFITTTTSISQYRCISYFPSGYFGLRVEPSPLPTRYQNISPTEGPVSNPQPAAHPWFPMPMATDTSAASLSRPNPQSSSVSEHLPNYH", "length": 402 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287A7E2-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258743", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGQRNSTSLHDFILLGFSDHPKLEMALSGVVATFYLITLVGNTAIILASLLDSHLHTPMYFFLRNLSFPDLCFTTSIVPQMLVNLWGPHKTISYGGCVIQLYVYMWLGSIECLLLAVMSYDRFTAICKPLHYLVIMNPHLCLKMIIMVWSISLANSVVLCTLTLNLPRCGNNLLDHFLCELPAMLKVACIDTTAVELSVFALGIAIVLTPLILILISYGYIAKAVLRMKSRAGQRKAINTCGSHLTVVSIFYGAIIYMYLQPGNNASRGQVIFLTLFYTIITPSLNPLIYTLRNKDMKEALKKLMRVDHKSTKSKRTWKS", "length": 320 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287A7J9-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258750", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEQNNGTEVKEFILLGFAGQHKSWLVLFIVFLGIYVVTLVGNIGMILLIKIEASLHTPMYFFLQNLAFVDLCYATAITPKVLQNLMSTEKSISFIGCMVQLFVYGTFVTSDGYILAAMAVDRYVAICNPLRYPTVMSQRVCIQLLIGSCFMGFLNACVNGSLTFQLNFCKSNKINHFFCDAPPILALSCSSIYFNIMLLAAFVGFNLMFTVSIIIFSYIFILAAILKISSAAGRKKAFSTCGSHLTAVTIFHGTLSYMYLHHRTLESQEQEKLASVFYGIVIPMLNPLIYSLRNQDVREALKEIGKKML", "length": 309 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287A951-1", "protein_name": "Small ribosomal subunit protein uS8", "gene_name": "LOC100514137", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MVHMNVLTDALESINNSEKRGKRQVLTRLCFKVIVRFLTVMMKHGTPIGKFEIMDDPRARKIVVNLTGRLNKCGVISPRFDGQLKDLEKWQNKLLPSCQFGFIVLTTSAGIMHHEEAR", "length": 118 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287ACV2-1", "protein_name": "HSF-type DNA-binding domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAHAPSEIQGVSPKDAPTGSESSITSPWCDNSITGDLDLRSQIEEKAFQALSEGSLIKEPCHTLCASEPDGDNDFPPLPFPRKLWEIVESDRFKSIWWDENGTSIVINEERFKKEVLERKAPFRIFETESMKSLVRQLNLYGFTKLRRNFQRPASLANILAEDNEDSAWNKLQFYHNPNFKRGCPNLLVRMKRRVRVKNASPVSASLLQGCSKKRSRTGGDVDNHNSDVAAETRGEDAFSTSTNLNVPLIRWPSMSQRISNTTTPTRSGLSSPSSPSVRPPGQIVMAQHAIFSQLTTFHMHSQSSYSPASGHIVNFITTTTSISQYHRISNFPSGYFGLRVEPSPLPTRYQNISPTEGPVSNPQPAAHPWFPMPMATDTSVASLSRPNPQSSSISEHHPNYY", "length": 402 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AEV7-1", "protein_name": "Uncharacterized protein", "gene_name": "WFDC10AL", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MKWWGLQWLMLSCLAILPASGNWQERISASLEALTQSKLIPGMKPCKTIPTKEQCTYFCDLPRACPTGLLCCSASCGNVCMPPKGHGNRRSSHKISNFLFTAEPIKQQ", "length": 108 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AF12-1", "protein_name": "Large ribosomal subunit protein eL21", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTNTKGKRRGTRSMSSSPFRKHGVVPLATYMRIYKKGDIVDIKGMGTAQKGMPHKCYHGKTGRVYNVTQHAVGTVVNKQVKGTILAKRINVHIVHIKHSKRGDNFLKRVKENDQKKKEAKEKVTWVQLKHQTAPAREAHFVRTNGKEPELLEPNP", "length": 155 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AGK9-1", "protein_name": "DM domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDPDEMPTVPCCPLDSTTGLETGAPWGIEFGPRRAIRRCARCHNHGITDQIKDQEHLCLFQACECHKCVLFSEHCSILPAESALKTMQELHLKRQLTQGLIKSGTTSPKAHSHVKKSSIQTGVLSKLPRCSADRSGIGIFVSVLDSSTLEEATNNFTFQEVTQAPCPAQQAPKTSDQDSDSASLEWQRKLEAAEALLTLRESSQAPSGPTPLLQPSAAPAPAGERGLQPPSRSLRPRPASSISLPIGHVGCISLLS", "length": 256 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AKK8-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "LOC100155397", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDVRNHSIVSEFVFLGFTNSWEIQLLLFVFSFLFYSSSMMGNLVIVFTVTLDSHLHSPMYFLLANLPAIDMVFCSITAPKMIGNIFKKHKAISFCGCITQIFFTHAAGGTEMVLLIAMAFDRYVAKCRPHHYLTIINPRICLCFLVTSWIIGLIHSMAQLFFVVDLPFCDLNVLDSFYCDLPRLLRLACTDTQELQFMVTVNSGLLSMGSFVLLIISYIFILFTIWKHASGGSSKALSTLSAHITMVVLYFGPLIFFYTWPSPTSHLDKYLAIFDAFITPFLNPVIYTLRNKEMKVAMRRLFSHLVHYRNIS", "length": 312 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AP00-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258730", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "SRHDLHCSLWQDNSMSVKRFAFARFSEVTEQCFLLFTLILLMFLASLTGNALIATAIWTNPVLHTPMYFFLANLSLLEIGYTCSVIPKMLQSLVSEARGISREGCATQMFFFAFFGISECCLLAAMAFDRYMAICSPLHYATRMSRGVCDHLAMVSWGVGCMAALGQTNYIFSLDFCGPCEIDHFFCDLPPILALACGDTSHNEAAVFVAATLCISSPFLLIIASYGRILAAVLSMPSPEGRRKALSTCSSHLLVVTLFYGSASVTYLRPKASHSPGIDKLLALSYTVVTSMLNPIIYSLRNKDVKAALRRTLGKKKVLAHR", "length": 322 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287ARD5-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258934", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDGKNQTALSEFIILGFSNLNQLQFLLFTIFFLTYICTLGGNTFIILVTVVDPRLHTPMYHFLGNLAFLDICYTTTNVPQMMAHLLSEKKSISYGGCMAQLFAFIFFVGSECLLLAAMAYDRYIAICKPLRYSVIMNKVLYSQLAASCWSGGFLNSAVHTVLTFRLPFCGNNQINYFFCDIPPLLVLSCGDTSVNELALLSIGVVIGWTPFLCIVLSYLYIISTILRIRSSKGRQKAFSTCASHLTIVLFYYGSAIFTYVRPISSYSLEKDRLISVLYSVVTPMLNPIIYTLRNKDIKEAMKAVGRKWQLPLLSFDV", "length": 317 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AT12-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MLSFNRTGVSHTVFYLLGIPGLEDQHLWISIPFFISYVTALLGNSLLIFLILTRRSLHEPMFLFLCMLAGADLVLSTCTVPQALAIFWFRAGEISLDRCITQFFIIHCIFMSESGILLVMAFDRYVAICYPLRYTTILTHTLIGKIGVTIFLRSYCTVFPIIFLLKRLTFCRNNVLPHTGCEHIGLAKYACNDIRVNIWYGLFVIVSTLFLDILLIFVSYMLILRAVFHMPSQDARHKALSTCGSHVCIIILFYGPGILTTLAQRFGRHIPAHIHILLANVCVLAPPMLNPIIYGIKTKQIQEQVAHLFLKQK", "length": 313 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AUC4-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MERINKSHPEEFILLGFADRPWLELPLFIILPMYFFLTNLSFLDMCYTTSIVPQMLFHLGGSEKTISYLGCAVQLYFFHTMGGTECLLLALMSFDHYVAICKPLHYTLIMNRCTCILLVATVWLSGMTYAVSEATVTLHLPLCGHNTLDHLICEIPVLIKAPCGEKGTNELTLSVVCIFMLAVPLCFILASYASIGHAVFKIKSSEGRKKAFGTCSSHLIVVFFFYGPDISMYLQPPSSISRDLPKFMALFHGVVTPTLNPFIYTLRNKDVKGAWGNLVRSVFTSK", "length": 286 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AXC2-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEQNNGTEVNEFILLGFAGQHKSWLVLFIVFLGIYVVTLVGNIGMILLIKIEMLQNFVGTEQSISFIGCMVQLLIYGAFVTSDCYILAAMAVDRYVAICNPLRYPTVMSQRVCIQLLIGSYLIGFLNASVHVSFILPLNFCKSNKINHFFCDAPPILALSCSSIYFNVMLLAAFVGFNLTCTVLVVIFSYIFILAAILKISSAAGRKKAFSTCASHLTAVTLFYGTLSYMYLHHRTLESQEQEKLASVFYGIVIPMFNPLIYSLRNQDVREALKGVGKQCF", "length": 281 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AY25-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100155405", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAHTNESVVLEFVLLGLTNSWELQLFLFAIFSIVYVTSVLGNTMIIVIIASDSRLNSPMYFLLSNLSFIDICQSNFATPKMLVDFLVEHKTISFEGCMAQIFLLHSFVGSEMMLLVAMAYDRFIAICKPLHYSTIMSRRLCIIFVFISWAVGILHSVSHLAFTVDLPFCGPNEVDRFFCNLPLVIELACMDTYKVEILTLTNSGLISLGCFLALIISYTVILITVHRWSSSGSSKALSTLTAHITVVILFFGPCIYFYIWPFSRLSVDKFLSVFYTVCTPLLNPIIYSLRNEDVQSAMHKWRNHHVNSWKY", "length": 311 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287B1Z6-1", "protein_name": "Short stature homeobox", "gene_name": "SHOX", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEELTAFVSKSFDQKSKESSGGGGGGGGKKDSITYREVLESGLARSRELGGSDSNLQDITEGSGHCPVHLFKDHVDNDKDKLKEFGTGRAAEGIYDCKDKREDVKSEDEDGQTKLKQRRSRTNFTLEQLNELERLFDETHYPDAFMREELSQRLGLSEARVQVWFQNRRAKCRKQENQMHKGVILGTASHLDACRVAPYVNMGALRMPFQQVQAQLQLEGVAHAHPHLHPHLAAHAPYLMFPPPPFGLPIASLAESASAAAVVAAAAKSNSKNSSIADLRLKARKHAEALGL", "length": 292 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287B9C9-1", "protein_name": "HSF-type DNA-binding domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAHAPSEIQGVSPKDESTGSESSITSPWCDNSITGDLDLRSQIEEKAFQALSEGSLMKEPCHTLCASEPDGDNDFPPLPFPRKLWEIVESDRFKSIWWDENGTSIVINEERFKKEVLERKAPFRIFETESMKSLVRQLNLYGFTKLRRNFQRPASLANILAEDNEVSAWNKLQFYHNPNFKRGCPHLLVRMKRRVRVKNASPVSASVLQGCSKKRSRTGGDVDNHNSDVAAETRGEDAFSASTNLNVPLIRWRSMSQRISNTTTPTRSGLSSPSSPSFRPPGQIAMAQHAIFSQLTTFHMHSQSSYSPASGHIVNFITTTTSISQYRCISYFPSGYFGLRVEPSPLPTRYQNISPTECPVSNPQPAAHPWFPMPMATDTSAASLSRPNPQSSSVSEHHPNYH", "length": 402 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BB76-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100157512", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAHTNESVVLEFVLLGLTNSWELQLFLFAIFSIVYVTSVLGNTMIIVIIASDSRLNSPMYFLLGNLSFIDICQSNFATPKMLVDFLVEHKTISFEGCMAQIFLLHSFVGSEMMLLVAMAYDRFIAICKPLHYSTIMSHRLCIIFVFISWAVGILHSVSHLAFTVDLPFCGPNEVDSFFCDLPLVIELACMDTYKIEILTLTNSGLISLGCFLALIISYTVILITVHRWSSSGSSKALSTLTAHITVVILFFGPCIYFYIWPFSRHSVDKFLSVFYTVCTPLLNPIIYSLRNEDVQSAMHKWRNRHVNSWKY", "length": 311 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BC21-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100152520", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDGKNQTALSEFIILGFSNLNQLQFLLFTIFFLTYICTLGGNTFIILVTVVDPRLHTPMYHFLGNLAFLDICYTTTNVPQMMAHLLSEKKSISYGGCMAQLFAFIFFVGSECLLLAAMAYDRYVAICKPLRYSVIMNKVLYSQLAASCWSGGFLNSAVHTVLAFRLPFCGNNQINYFFCDIPPLLVLSCGDTSVNELALLSIGVVIGWTPFLCIVLSYLYIISTILRIRSSKGRQKAFSTCASHLTIVLLYYGSAIFTYVRPISSYSLEKDRLISVLYSVVTPMLNPIIYTLRNKDIKEAMKAVGRKWQLPLLSFDV", "length": 317 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BF45-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100513333", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRNRTITTFILLGLTDDPELQVLIFIFLFLAYMLSLTGNLTIITLTFVDSHLKTPMYFFLKNFSFLEVSFISSCIPRYLYSIATGDKIITYNACFIQVCFTDLCGITEFFLLAAMSYDRYVAICKPLHYVTIMSSRVCGILISSCWMAGLCVLIPPLSLGLNLKFCDSNRLDHFGCDAFPLVKISCSDTWPMEQTVIICAVLTLNMTLTCVVLSYAYIIKTIFRFPSDQQRKKAFSTCSSHMIVVSITYGTCIFIYMNPTAKGEVTIKKVVSLLIFSVSPTLNPFIYTLRNNQVKRAFKDSIKRIALLSTR", "length": 311 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BGE2-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MENNQSWIAEFILVGFQLSEEMELFFFIIFFLLYIFNLLANGMILGLICLDPRLHSPMYYFLTHLAVTDISYASSNLPNMLENLVKHKKTIPFVSCTLQMLFYLAFASVECLILVVMSYDRYVAICHPLQYTVIMNWKLCTVLAIISWACGFFLALVQVSLFLRLPFCGPQKVNHFFCEIRSVLKVTCGETWINKIFLFADGVFILVTPISLMLVSYVRILWAILKIQSKEGRKKAFSTCSSHLCVVGFYFGIAMMVYLVPDDSHQQEEQQKILFLFYTFFNPLLNPLVYSLRNAQVKAAFHRIFQKNRTM", "length": 311 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BIM6-1", "protein_name": "Histone H2A", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MPGKRSRRKSPGRQGRTCARTTRAGLSASVSHMERLLREGPYAQCLSSSARVFLAATIEYLTARVLELAGDEAQIVGRRCITPELVAMAVHNNALLSAFFGTLAISQVAPTQE", "length": 113 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BK27-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MVTEFIFLGLSNSQELQTFLFVFFLVFYVGIVFGNLLIVLTVMIADFFRKCKVISFKGCLAQIFLLHFFGGSELVILIAMAFDRYVAICKPLRYTTIMSSNVCVGIVAAAWGTGFLHSVSQLAFAVNLTFCGPNEVDSFYCDLPRVIKLSCTDTYRLDIMVIANSGVLTVCSFVLLIISYTVILVTIQHLPSQKSSKALSTLTAHITVVLLFFGPCIFIYAWPFPIKSLDKFLAVFYSVVTPLLNPIIYTLRNKDMKTAMKRLRKWNMNSRIKP", "length": 274 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BKA6-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110259008", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTFNCSLWQDNSMSVKRFAFARFSEVTEQCFLLFTLILLMFLASLMGNALIATAIWTNPVLHTPMYFFLANLSLLEIGYTCSVIPKMLQSLVSEARGISREGCATQMFFFAFFGISECCLLAAMAFDRYMAICSPLHYATRMSRGVCVHLAMVSWGVGCMVGLGQTNYIFSLDFCGPCEIDHFFCDLPPILALACGDTSHNEAAVFVAATLCISSPFLLIIASYGRILAAVLSIPSPEGRRKALSTCSSHLLVVTLFYGSASVTYLRPKASHSPGIDKLLALSYTMVTSMLNPIIYSLRNKEVKVALRRTVGKKKVLAHR", "length": 320 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BKW4-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258932", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEGENQTVLFEFIILGFSNLKELQFLLFTIFLVTYICTLGGNSFIILVTMTNLHLHTPMYFFLENLAFLDICYTTTNVPQMMAHLLSEKKSISYLGCMAQLFAFIFFVGSESLLLAAMAYDRYIAICKPLRYSVIMNKVLYSQLAASCWSGGFLNSAVHTVLAFRLPFCGNNQINYFFCDIPPLLVLSCGDTSVNELALLSIGVVIGWTPFLCIVLSYLYIISTILRIRSSKGRQKAFSTCASHLTIVLLYYGSTIFTYGRPISTYSLEKDRLISVLYSIVTPMLNPIIYSLRNKDIQEAMQVMGRKWKASSSLSFDV", "length": 318 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BLZ6-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "LOC110258167", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAGGKNSTTITKFILLGFSEFPKLTAVLFSVFLRISLMTVSWNMGLIMLIRMDSHLHTPMYFFLSNLSLLDICYVSTIAPRMLSDFFKKYKFISFMGCTMQYFFSSLALTECCLLAAMAYDHYAAICNPLLYTAIMSPTLCVQMVAGSCVTGFFGSFIQLCALFQLHFCGQNVTNHFFCDLPQLLILSCSDTFFFQVMTSVLTVIFGLTSVLVIIISYGYIIATILKITSSEGRSKAFNTRASHLTAVTLFFGSGIFIYMYPNSGDSLSQNKLVSVLYTVIISMLDPLIYSLRNKEIQDSLSRWRKTIFSWCY", "length": 313 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BNL4-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "TVLNARNVSTPKVFILLGFSDHPWLEMPLFIIVLAAYIRTLVGNISIIVVSRVDPNLDSPMYFFLSNLSFLDLCFTTTTIPQLLLNLWGPDKSISYGGCVTQFYMFHFWGATECIFLAVMSMDLQAICKPLRYPVIMHQQLCIFLVVMAWLSGLVNSLLQSSLTIQLPLCGNNKVDDFLCEVPVMIKMSCTDTTFNVAMLSIVGTFYSLVPLSLILVSYGFIVATVLRIQSSEGKKKAFNTCSSHTIAVSLFYGPVISMYVQPSAANSQDKNKLMSLFYSLVTPMLNPFIYTLRNKDMKGAMMRLLVSLYHQRRG", "length": 315 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BSD4-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100525471", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MENENSTVVAEFIFVGLTQSRNIQLLVFVLILIFYLIILPGNFLIILTIRSDPGLTAPLYFFLGNLAFLDASYSFIVAPRMLVDFLSEKKVISYRGCITQLFFLHFLGGGEMLLLVVMALDRYIAICRPLHYSTVMNLRACYALLVALWLGGFVHSIIQVALILHLPFCGPNRLDNFFCDVPQVIKLACTDTFVVELLMVFNSGLMTLLCFLGLLASYAVILCRVRGSSSEGKTKAMSTCTTHIIVIFLMFGPAIFIYTRPFRAFPADKVVSLFHTVIFPLLNPVIYTLRNQEVKTSLKRLLNQQLA", "length": 307 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A2R8VHJ9-1", "protein_name": "Predicted gene, 36245", "gene_name": "Gm36245", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSTKNEEQNEDQSEGVVIPHIQDHHCLAILAFCFFFPLGYLAYRSSCKTRTYIEQKEYEKAKATSRCTFAFVLSSIAGGSIIFFCLFSRLFFM", "length": 93 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A3L7ICH5-1", "protein_name": "Cytochrome c oxidase subunit 7A2-like, mitochondrial", "gene_name": "LOC100756118", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MYYKFSGFTHKLAGAWALESYSPQGLKPVASTEAPPIVFATPTKLTSSVTAYVYAGKNKVPELQKFFQNFFHLKRGLPDQMLYRTPMALTVGGTIYCLSALYMASQTPNK", "length": 110 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A3Q1LL21-1", "protein_name": "BTB domain-containing protein", "gene_name": "LOC112445444", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGPLNSRNLQCRESGTGELQQPEAQAGPSYVSGSRKRKQSTGPSLGPESEMSHNQEEDLQQVVCTRQGKKVKIKSEYAYQTLFLNGETSDIKIRALGKVWCLHKRFLCQSDYFATMFRDSGKECHKDIIDLEINDQNINVESLQFVLGSLYRNEYVLIKPLQVPRVLATACLLQVEDLIQQCDKTMKETINVKTVCSFYVAAETYGLHSVKTGCFEWLLHNLMTHPSVELYKKLSTDLMNLVISSSNLFVMQKEIDIYTTLKQWMFLRLNPGWKGTMKQLLVNANNWFSRHKEHDGSISFLETKQGIVFQPVFKNLRFQHIICDLASTKVIEQDALIPSEWLSCVYKRQWYTLLRAQQYREIGPRDITETELEEYSMRCGKRIVRDGTYAWKWSGYNFGVHLYVVFTSHFIIFKRHAFSQPYDGSICLQPQRNIAFRLTLVYFGSSGKLSFRKTTGYKILTFEKDEEQMVMKLDSVALSFPLYIFCNFLFISLENPGN", "length": 498 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q1LLV6-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MNLFIYVLLLSIWTSSCLDRNESNGSATAVTTHAEFKQTKLQELRRRLLIIIIGTLITGYMVTCTCFLHYSCDSEEAHKATKDKKEDITIKASRSSKISFTDSKSPTAGLGDPERQSVVSRIDKSSGPSSPRKVPSSAEKLVRPSSQKKPSKPSAPKKVLGSPPQEKLHRTRSPKKAHRQAHAHKLVSQVSPSYPEKAIKPTWPPSLQCRVKPTKTPLPYPKNQSFPEHSSADKLTKRQRYLKLKCPASAGRAEILSRPQPVKFCRCYKEKCLVCRAVSEPFITHVSEANKKHVPVPLFSRELKHFYKSYKKKQPKYNTLYGNMSDSDITTYNSDGESDREVIIMCNIKCKEDIYKNSPNN", "length": 361 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q1LUU6-1", "protein_name": "Guanylyl cyclase domain containing 1", "gene_name": "GUCD1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MTGPRCRRKQRPSGRPGPRGTRAPQHPTPDAGWTARRAAGAAGAEARGRDLPPQRKPAKPTAPGKGRPERGECPRRADRGGGDPEERAGGRPAWGPGAGRGGAWGRSRLPPLLPPGRWCWRPGKPARAGRALSSPVDARAAAGAGPGPWEPRAARVMRTEVDAEAAGPPLEPDEPTQSLSIQDQETAFLLEDSCQLKPGQPLPGRPWPSGDFVQLPVPIIQQLYHWDCGLACSRMVLRYLGQLDDAEFEQALQELRLTRSIWTIDLAYLMRRFGVRHRFCTQTLGVDKGYRSQSFYRKHFDTEETRVNQLFAQAKTCKVLVEKCRVSVQDIQAHLAQGHVAIVLVNSGVLRCDLCSSPPKYCCFTPSGPRCFCRSPDYQGHFIVLRGYSRAAGCVFYNNPAYADRMCSASISNFEEARTSYGTDEDILFVYADS", "length": 434 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q1M0W3-1", "protein_name": "IF rod domain-containing protein", "gene_name": "LOC787600", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MTCGSACFSSRSGVRSSSSCVTTQRYAPGRTFSCVSACGPRPSRCCITAAPYRGVSCYRGLTGGFSSRSVCGGSRAGSSSRSFGYRSGGPSPPCITSVSVNQSLLKPLNLEIDPNAQRIKHQEKEQIKSLNSKFAAFIDKVCFLEQQNKLLETKWKFYQNQRCCESNLEPLFNGYIETLRREAERVEADTGRLASELNSLQEVLQGYKKKYEEEVALKTTAENEFVKIKQEVNRAYVLKGDLEANAHSLVEEVGFLKTLYEEELRVMQAHISDTSVVVKMDNSRYLNMDSIVAEIKAHYDEIASRSRAEAESWYRSKYEEIKATVIRHGETLRRTKEEINELNRLIQRLTAEIENAKSQNSKLEAAVTQAEQQGEAALNDARGKLAGLEKTLQKAKQDMACLLKEYQEVMSAKLGLDIEIATYRRLLEGEEQRLCEGISAVNVRVSSSRGGVVCGDLSATRTCGIGSYGVGACGSSCKKC", "length": 480 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q1MFB0-1", "protein_name": "Uncharacterized protein", "gene_name": "LOC112441459", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MNLFIYVLLLSIWTSSCLDRNESNGSATAVTTRAEFKQTKLQELWRRLLIIVIGTLITGYMVTCTCLLHYSCDSEEAHKAAKDKKEDITIKASRSSKISFTDSKSPTAGLGDPERQSVVSRIDKSSGPSSPRKVPSSAEKLVRPSSQKKPSKPSAPKKVLGSPPQEKLHRTRSPKKAHRQAHAHKLVSQVSPSYPEKAIKSTWPPSLQCRVKPTKTPLPYPKNQSFPEQSSVDKLTKRQRYLKLKCPASAGRAEILSRPHPVKFCRCYKEKCLVCRAVSEPFITHVSDANKKHVPVTLFSRELKHFYKSYKKKQPIYNTLYGNMSDSDITTYNSDGESDREVIIMCNIKCKEDMFKNSQNN", "length": 361 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q1MI36-1", "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGSSSGSKAEFIVGGKYKLVRKIRSGSFGDMYLAINITNGEEVAVKLESQKARHPQLLYESKLCKILQGEVGIPHIRWYGQQKDYNVLVMDLLGPSLEDLFNFCSRRFTMKTVLMLADQMMGRIEYVHTKNFIHRDIKPDNFLMGIGRHCNKLFLIDFGLAKKYRDNRTRQHIPYREDKNLTGTARYASISAHLGIEQSRRDDMESLGYVLMYFNRTSLPWQGLKAATKKQKYEKISEKKMSTPVEVLCKGFPAEFAMYLNYCRGLRFEEAPDYMYLRHLFHILFRTLNHQYDYTSDWTMLKQKAAQQAASSSGQGQQAQTPTGF", "length": 325 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q1MQ28-1", "protein_name": "Ig-like domain-containing protein", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "KEQVLQPTTVVSLEGAVAEISCNHSVSDVYDFFWYLHFPGFAPRLLIKGLGPSQQGRYNMTYERFSSSLLILQVQTADAGVYYCALRYTEAGHP", "length": 94 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q1MT47-1", "protein_name": "Uncharacterized protein", "gene_name": "LOC112444909", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MLGCEGGKRPLKPPKKQAKETDEEGKAFKHKQKEEQKTLEGLKGQIMGKVPLATGGIKESGKQ", "length": 63 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q1MUP8-1", "protein_name": "E3 ubiquitin-protein ligase", "gene_name": "LOC100336539", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSRLTERALPTGTSNGAPSSRRAPVLTGTTVSNNDLASLFECPVCFEYVLPPITQCKSGHLVCGNCRPKLTRCPTCRVPLTSIRNLAMEKVANLVLFPCKYTSSGCGKTMPPTEKADHEEHCEFRPCRCPCPGTSCGWQGSMDAVVPHLMQHYNESIITLRGEVVVFLAVNINLAGTLEWVMLQSCFGFHFLLVLEKLEIYDGHQKFFAVVQLIGTREQAENFTYQLELNGNRRRLSWEATPLSIHEGIATALINSDCLIFDSEVAELFAENGNLSIDVTISMC", "length": 284 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q2TUK0-1", "protein_name": "Uncharacterized protein", "gene_name": "LOC121109925", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MEQQGHGERGNWQTKVWKTVALVLVTVAVASFGVYCVGGLVEGIKTTAGVTARLVRRDGEIVSLDEELAKVQRQLHVLQWRARDITERALHEALRRTELPGFTGEAVQKIIHQVLEKLEESPFQMTNYASKTSGAAIVRSKTSPSWIGSGRVFWQSLPLVAYMRPPEVILEPDNHPGNCWPFPGSQGHVFIKLPVAVFPTAVTINHGVPAAAYHADSISSAPKDFAVYGLQEEDDEKGTLLGEFIFMPGQAPGQTFQLKNEHSAFIKYVRLQVLSNWGHPEYTCVYQFRLHGDPAPDGDARGKLSA", "length": 306 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A3Q2UEY0-1", "protein_name": "Mab-21-like HhH/H2TH-like domain-containing protein", "gene_name": "LOC124418381", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MALVLVLALLVRALIVSGSDHAVMLERVQQHEKEQRNGEQSWVDMPALLFTLLHYWKIWLCTGLFVFLFWNMWRSLKRKQHEEGGQQEQQEREEQVEEVEPEEQQEQVEQEEQLERVEELERVDQVEHVEQEEREDQGEQVQQEEQVEEVEREDEEDEYFYHSALTRYIARRAWEKMQGRATKCVLVEELMRDLLQTFTFVCPNSFYPVLQPAIGVGSAFEGWSPCEEDIVYHLLVPIKAPHGHVFHPELGEEGDMLARNSRIRVELVCMCTREQQLGDVLCFLHHSQEELSQNQQPSLLQTLCTGSYLDVQKTAAWFNKQVPRIWRLTHRAHRYGLKVLPSSRSCKLQVTDTSSGEKVHVELLFGVQQGNLDIFLSSQNAEAVFTPSTTWPQSCAVAERKYFEYVARTAGPNSCHLVCLRLFAHILVGMGFSSYTIKTLLLHLLAIIPLEDWRRRHFLSRLENLLQYLQYCLNDKLLNHFLLGNATMPDEVVLPQAFQTASPLNLFQHLEQDPDAHSRALRDFKELKDRLFRLLLFGR", "length": 539 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A494C0N9-1", "protein_name": "Protein FAM246B", "gene_name": "FAM246B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MATPGRPWAQARSAYRASEVLRRVTGRRRDPGPQSNGPGREDARAPGRLARLLRQLRAEAASRSEVPRLLKLVERAGAGAAGAGERTGAHSRGSVCSVCGEPRGRATYPAGVLEVSERRLQEGLAAVREELGAEIEALRAELRAELDALRALLPPPPPSPPARREPRAVPRAAPRGPTLLRTLGTVSALVAASRPADDAPDGPAECGAHRAPARKNHKKMPVPPGAPQGGGD", "length": 232 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A494C0Z2-1", "protein_name": "Speedy protein E13", "gene_name": "SPDYE13", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGQILGKIMMSHQPQPQEERSPQRSTSGYPLQEVVDDEVLGPSAPGVDPSPPRRSLGWKRKRECLDESDDEPEKELAPEPEETWVAETLCGLKMKAKRRRVSLVLPEYYEAFNRLLEDPVIKRLLAWDKDLRVSDKYLLAMVIAYFSRAGLPSWQYQRIHFFLALYLANDMEEDDEAPKQNIFYFLYEETRSHIPLLSELWFQLCRYMNPRARKNCSQIALFRKYRFHFFCSMRCRAWVSLEELEEIQAYDPEHWVWARDRAHLS", "length": 265 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A4X1TRA8-1", "protein_name": "Small ribosomal subunit protein eS19", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MPGVTVKDVNQQEVVRALAAFLRKSGKLKVPEWVDTVKLVKHKELAPYDENWFYTRAASTPRHLYLWGIAGVGSMTKTYRGHQRDRVMPSHFSRGSKSVAHRLLQAREGLKMVEKDQDGGRKLTPQGQRDLDRIAGQVAAAKKKH", "length": 145 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A4X1TY10-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100627324", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MENYNQTSIYFILLGLFPSSRIGMFLFIIIVLIFLIALFGNFSMILLIFLDNNLHTPMYFLLSQLSLMDLTYISTIVPKMAYNFLFNDKSISFIGCGIQSFFFLTLAGAEGLLLAAMAYDRFVAICFPLHYHIRVSKRICVLMIIGSWIMGSINSFAHTAYALNIPYCQSRAINHFFCDVPAMLTLACIDTWVYESTVFVSTTIFLLVPFTCIAFSYGRILLVVHHMNSTEGKKKAYSTCSTHLTVITLYSAPFAYTYLRPKFLRTPTEDKVLAMLYTIFTPMLNPIIYSLRNKEVMGALRRVIQRICSVKM", "length": 312 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A4X1U699-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100524234", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRRENQSSVSMSKFVLVGLHIWPEQQGMVFALFLGMYLTTVLGNLLIILLIRLDPRLHTPMYFFLSHLAFSDVSFSSVTVPKMLMNMQTQDQSIPYAGCVTQTYFFIFFSCIDNLLLAVMAYDRYVAICHPLRYAIIMKEELCLCLLAGSWLLSCAYALTHTLLLAQLSFCADNIIPHFFCDLASLIKLSCSDTSLNELVIFSLGPAVFIFPLSGILVSYGCIVVSILSVHSPKGIFKALSTCGSHLSVVSLFYGTSMAVYLSSSSGQSHDKDTIASIMYTVVTPLLNPFIYSLRNRDMTLALQILFRNSNLLAK", "length": 315 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A4X1VK25-1", "protein_name": "Elongin-C", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "RSYGGCEGPDASYGKLIASDKFIVKREHVLTSGAIKAMFSSPGQFAEKETDVVNFRETPSGIPSAALWKVCMYLPHKVCYTSNTSEIPEFPINSEFPIAPDIALEPLMAANLLDC", "length": 115 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A571BD55-1", "protein_name": "BTB domain containing 35, family member 26", "gene_name": "Btbd35f26", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGKTWCLHKVFLCQSVYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A571BF50-1", "protein_name": "WD repeat domain 88", "gene_name": "Wdr88", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTKDNEEILNSPDQVRKGSPDVKKKKKIKKKRVKPKGDLDSKKLDFVEDSWWKGSLKNKNLDFAEYNWVLVDNRRVSVDSRKSSADSKRGSADSKRGSADSKRGSADSKRGSADSKRGSVDSKRGSVDSKRGSVDSKRGSVDSKRGSVDSKNRFSPKKMDFSEDREISQPTFLRAQQSKVPWALMRALGLFKLSLPDIRRYYNLTSHDPLALDKDRQPREKSHMATVKKFWGNQQPLSKIPYKILIGHDHIVSSCHFCMNDTRFLSSSYDCSVKLWDAEDGTVIWDFEPRPKAPVLECSITADNRRIVASSYDKTVRAWDVETGQLLWKVRHDTFVVCCKFSPNGKFVLSALDVDRGIYLMDPENITTVIHMKDHHQRSITSCCFDPDSQKVASVSMDRCIKIWDITSRTTLFTIPKAHYNAISDCCFTSTGHFLCTSSWDKNIKIWNVHTGEFRNRGACVTLMKGHEGCVSSCCIARDSSFLISGGFDKTVAIWDVGGGYRKLALKGHEDWVTDVAISNNKKWILSASKDSSMRLWNIEEIDKIPLVSENKKAMGLKVRQVGIR", "length": 565 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A571BG45-1", "protein_name": "BTB domain containing 35, family member 25", "gene_name": "Btbd35f25", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGLQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A571BG86-1", "protein_name": "BTB domain containing 35, family member 8", "gene_name": "Btbd35f8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLSCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESRHGVINLIIKNEDIDTRSLHFVFGALYRDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A5G2QG78-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100523228", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTRGENTTNITDFVLLGFSDFPQIRAALFVVFLVIYILTLTWNLCLIVLIRMDSHLHTPMYFFLRNLSFIDICYVSSTAPKMLYDFFQAKPTITVVGCAIQYFVCSTMGLSECGLMTVMAYDRYAAICNPLLYSSTMSPSLCGRMVLGSYMAGLSASLSQVCAMLQLHFCGPNVIHHFFCDMPQLLVLSCSDTFFLQLLTLVLTVIFGILNALVIMMSYVYIVISVMKITSTKGWSKAFNTCASHLTAVTLFYTSIIFVYLSSSSGGSSGLDRFAAVFYTVVIPMLNPLIYSLRNKDIKDAWKRLKKRKECC", "length": 312 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A5G2QIN7-1", "protein_name": "ADAM metallopeptidase domain 7", "gene_name": "ADAM7", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSNSHYLSALFSREFLASNYSETYYSTKGEEVTTHPQIMDHCFYQGSIIHEFDSAASISTCSGLRGFFRVNDQRYLIEPVKYSDEGEHLVFRYNPKVQHAANYSCTELNFTRTAVLKDNTKSMEDSKMESIEKEKHIELFIVADNNVYHRNPNSKVRNRVWGMVNFVNMIYKTLDIHVTLVGLETWTNGDKIEIDSNIETTLKRFSAWQEIILKKKKNFDHVVLLSGKWLYTSAQGTSYPGGMCLPYYSSSVVKDLLPDLNTIASRMAHQLGHSLGMKHDDYPCTCTLGKCVMDSGGSIPALKFSKCSRTQYQQYLKDFKPTCMFDIPFSDKLSDYPYCGNKKLDDGEECDCGPVQECTNPCCDARKCMLKPEFTCAEGECCESCQVKKAGSLCRPAKDECDFPETCTGHSPACPKDQFQVNGFPCKDAKGYCFMGNCPTRDDQCSELFDNEAKDSSDICYKMNKNGNKFGYCKNEEQTLIPCEEKDVKCGKIFCTGGKHASILGEEKVYHLKKPLTQNVTECKTFFLYHKSKDFGLVAPGTKCGEGKVCSNSECVTIEKAYNSTDCPSPCNENAVEDGDLGCQCEGVQASVDWEETLNVTNISILVVVLILVIIGVLSAVLLIRYQKCIKLKQVQRPPSEALGVENKGYTGDEQQTRTEPILPDIHPLHRRTAESLARLPTSFSSPHYITLKPASKEPRGTADPNPSAKVSLKLDIQNGCASLS", "length": 725 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A5G2QM02-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100623139", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTGGENTTNITAFVLLGFSDFPHIRAALFVVFLVIYILTLTWNLCLIVLIRMDSHLHIPMYFFLSNLSFIDICYVSSTAPKMLYDFFQAKPTITVVGCAIQYVVFSTMGLSECGLMTVMAYDRYAAICNPLLYSSIMSPSLCGRMVLGSYMAGLSATLSQVCAVLQLHFCGPNVIHHFFCDMPLMLGLSCSDTFFVRVLTAVFTVIFGIINALVIMMSYVYIVISIMKITSAKGWSKAFNTCASHLTAVTLFYTSGIFVNLNSSSGGSSGLDRFAAVFYTLVIPMLNPLIYSLRNKDIKDALKRLKKRKECC", "length": 312 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A5G2QUE5-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100524011", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRRENQSNVSKFLLLGLPIQQEQQGMFFALFLGVYLTTVLGNLLIILLIRLDPRLHTPMYFFLSHLALTDISFASVTVPKMLMNMQAQDHSISYAGCVTQTYFFMFFACIDNLLLTVMAYDRYVAICHPLRYTIIMREELCICLLAGCWLLSCAYALTHTLLLAQLSFCVDNIIPNFFCDLAALLQLSCSDTSLNELVIYTSGAAVFIFPPSGILVSYGRIGISILRVPSTKGICKALSTCGSHLSVVSLFYGTIMALYFSPSFGQSHYKGIIASVMYTVVTPMLNPFIYSLRNRDMTLALEILIRNKNLFTT", "length": 313 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A5G2QWK6-1", "protein_name": "Calmodulin 3", "gene_name": "CALM3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "VSAEREEEGVALKFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEVTASPVLGPAREGPRASAPSWGGKQPLAIACNQPRRSSGFSWDLPSFENLLSSTLWSPASGDGRGVEHSGRPS", "length": 214 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A5G2R7Y6-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100524140", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGQRNQTSSLADFILEGLFDDSPAHAFLFSLTMVVFLVAVSGNTLTILLICADPRLHTPMYVLLSQLSLMDLMHVSTTIPKMAINHLSGTKSISFVGCATQYFLFLSLGGAECLLLTFMSYDRYVAICHPLRYAVLMNRKVGQMMAVMSWLGASVNSLIHTVILMHFPFCGHRNIHHFYCEFPAVVQLVCGDITVYEIAVYIGDIVLLLLPIVLISASYVFILHSVIHMHSAGGKRNAFATCSSHLTVVSLWFGACIFSYMRPRSQRTPLQDKVGSVFYTIITPTLNPLIYTLRNKDIAKALKRVLGREMITQNPKVRLP", "length": 320 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A5G2RGH3-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100524855", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGRRNQTSSLADFILEGLFDDSPAHAFLFSLTMVVFLIAVSGNTLTILLICADPRLHTPMYVLLSQLSLMDLMHVSTTIPKMAINYLSGTKSISFVGCATQYFLFLSLGCAECILLTFMSYDRYVAICHPLRYTVLMNRKVGQMMAVTSWLGASVNSLIHTVILMHFPFCGHRNIHHFYCEFPAVVQLVCGDITVYETAVYISDIVLLLLPIILISASYIFILHSVIRMHSAGSKRNAFATCSSHLTVVSLWFGACIFSYMRPRSQRTPLQDKVGSVFYTIITPTLNPLIYTLRNKDIAKALRRVLGREMITQNPKVRLP", "length": 320 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A668KLA6-1", "protein_name": "Predicted gene, 52955", "gene_name": "Gm52955", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNSSSEHCNVSDWLRLEATVKASVYVVAFSITTSLTIVIIAIVSQSLQLRKEVRLVLLCHHLLCISSYCGLGVVFQGMGALLANSPLLLCWLVFGAQLSVGEGILLTLTLMALNTYLAICYPLNSPSFVDSAKYRILAGTWTTVILKNVGLFLIEGTSPTPASVFQSAPLCPVILNGMPARVIGMFSLAFLLSVILVSYCLIYREGKRAGHFNKSNIKARRTVLVHLLQISLHVIPTLIIIGLGKQCGVFFFALNLALFGIFAFAQCFNPLVYGLHNRDLQSKLYPSLCCQKKLLP", "length": 296 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A668KLA7-1", "protein_name": "Predicted gene 7582", "gene_name": "Gm7582", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNSSSEHCNVSDWLRLEATVKASVYVVAFSITTSLTIVIIAIVSQSLQLRKEVRLVLLCHHLLCISSYCGLGVVFQGMWALLANSPLLLCWLVFGAQLSVGEGILLTLTFMALNTYLAICYPLNSPSFVDSAKYRILAGTWTTVILKNVGLFLIEGTSPTPASVFQSAPLCPVILNGMPARVIGMFSLAFLLSVILVSYCLIYREGKRAGHFNKSNIKARRTVLVHLLQISLHVIPTLIIIGLGKRCGVFFFALNLALFGIFAFAQCFNPLFYGLHNRDVQSKLYPFLCCRKKLLP", "length": 296 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A668KM50-1", "protein_name": "RIKEN cDNA A930007A09 gene", "gene_name": "A930007A09Rik", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSLSELPQKNTDLAEMQSGPLGRCSHFFWLGVAFDAVGVAVLFTGVFANLLFYDMLLYLGSIIIFVSLLWWISWYTGNIEALPEDPLRGTSPRESGVHRSGSRRFSLTLRSVSDTFQRIRRRRRRRLHPRVVQRISSISSTDPGQLERNCDARTSGGRALFRSAKPEAVLNQFSRVQTSKSLPLGIVHTGLSICTSRSQPVFSVTSQTYPLASDSNSQMAMSSDSHVYLDSHSQEHSKISVASQIYPLEREESQSHLLVIPDSLSMVPVTSQSQILPSVSSESCVPLGPHSQGRSKISVATQIYPLEREESQSHFLVIPDSLSMVPVTSQSQILPSVSSESCVPLGPHSQGRSKISVASKIYPLEREESQSHLLVIPDSLSMVPVTSQSQILPSVSSESCVPLGPHSQGRSKISVATQIYPLEREESQSHFLVIPDSLSMVPVTSQSQILPSVSSESCVPLGPHSQGRSKISVASKIYPLEREESQSHLLVIPDSLSMVPVTSQSQILPSVSSESCVPLGPHSQGRSKISVASQIYPLEQEESQSHFLVPMPSDSFPVVPMTSQSQIQGSLAQQSHLQNLPLASQTPETDKASKSHTLAKGVPGVPPGSAQTQHPQASLAQTSQISSPVRKVPKN", "length": 636 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A8C2LDI6-1", "protein_name": "Large ribosomal subunit protein eL33", "gene_name": "LOC100774916", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSGRLWCKAIFAGYKRGLCKQRGHTALLKIEGVYARAETEFYLGKRYAYVYKEKNNTVTLRCKPNKARVIWGKVTKAHGNSGMVHAKFRSNLPAKVIGHRIRVVLYPSRI", "length": 110 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8C2LMV8-1", "protein_name": "Large ribosomal subunit protein eL21", "gene_name": "LOC100755948", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MTNTEGKRRGTRYMFSRPFRKSEVVPLAMYMRIYKKGDIVDIKGMDTVQKGMPHKCYHGKTGRVYNVTKHAVGIIVNKQVKGKILAKRINVQMKHIKHSKSRDSFLKQVKENDQKKKEAKEKGTWVQLKRQPVPPREAHFVRTNGKEPQLLEPISYEFMA", "length": 160 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8C2LSR6-1", "protein_name": "Large ribosomal subunit protein uL5", "gene_name": "LOC100751955", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSQDEGEKENPMWELHICKLCLSICVEESRDRLTRAAKVLEQLKGETPVFSKARYTMRSFGIRSNEKIAVQCTVHGTKTEEILEKGLKVQEYELWRNNFTDTGNFGFEIQEHIDLAIKYDPSIRIHGLDFYVVLGRPGFTIADKHRTGCIGAKHRISKEEAMRWFQHKYDGIILPGK", "length": 177 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8C2LUM6-1", "protein_name": "Tubulin alpha-1C chain-like", "gene_name": "LOC100757824", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MCECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETDTGKHIPRVVFVDLEPTAIDEVRTGTYRQLFHPEQLITGNEDAANNYARGHYTIGKEIIDLVLDRIRKLADQCTGLQGFLVFHSFGGGTGSRFTSLLMEWLSVDYGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYPTPLPE", "length": 288 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8C2LZU4-1", "protein_name": "Glia maturation factor", "gene_name": "Gmfg", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSDSLAVCEVDPELKEKLRKFRFRKETDNAAIIMKVDKARQMVVLEEEIQNVSPEELRLELPERQPRFVIYSYKYLHDDGRVSYPLCFIFSSPVGCKPEQQMMYAGSKNRLVQTAELTKVFEIRATDDLTEAWLQEKLAFFG", "length": 142 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8C2M625-1", "protein_name": "U3 small nucleolar RNA-associated protein 15 homolog", "gene_name": "LOC100755487", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAGYKPVAIQTYPVLGEKITQDTLYWNNYKTPVQIKEFGAVSKVDFSPQPPYNYAVTASSRIHIYGRYSQEPIKTFSRFKDTAYCATFRQDGQLLVAGSEDGVVQLFDISGRAPLRQFEGHTKAVHTVDFTADKYHVVSGADDYTVKLWDIPNSKEIQTFREHSDYVRCGCASKLNPDLFVTGSYDHTVKMFDARTNKNVLCVEHGQPVESVLLFPSGGLLVSSGGRYVKVWDMLKGGQLLVSLKNHHKTVTCLCLSSSGQRLLSGSLDRKVKVYSTTSYKVVHSFDYAASILSLALSHEDETIVVGMTNGILSVKHRKSEAKKESLSRRRRPAYRTFVKGKIYMKQRDDIMINRPAKKHLEWYDKDLKSFRISKALDRVLEPNCVIKTPEVTVSIIKELNRRGVLANALAGRDEKEITRVLNFLIRNLSQPRFAPVLINAAEIVIDIYLPVIGQSPVVDKKFIVLQGLVEKEIDYQRELLETLGMMDMLFATMSRNDSVSLSENVPAELPEKTESPCQPGDTDKNS", "length": 527 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8C2MXE3-1", "protein_name": "Glycerol-3-phosphate acyltransferase 1, mitochondrial", "gene_name": "Gpam", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MDESSVTLGTIDVSYLPNSSEYSLGRCKHATEDWGDCGFKTTFFRSATLKWKESLMSRKRPFVGRCCYSCTPQSWERFFNPSIPSLGLRNVIYINETHTRHRGWLARRLSYILFVQERDVHKGMFATSVTENVLNSSRVQEAIAEVAAEMNPDGSAQQQSKAIQKVKKKARKILQEMVATVSPGMIRLTGWVLLKLFNSFFWNIQIHKGQLEMVKAATETNLPLLFLPVHRSHIDYLLLTFILFCHNIKAPYIASGNNLNIPIFSTLIHKLGGFFIRRRLDETPDGRKDVLYRALLHGHVVELLRQQQFLEIFLEGTRSRSGKTSCARAGLLSVVVDTLSSNTIPDILVIPVGISYDRIIEGHYNGEQLGKPKKNESLWSVARGVIRMLRKNYGYVRVDFAQPFSLKEYLESQSQKPTSAPLSLEQALLPAILPARPNDAAESEDTSSNEPRNTADEAFRRRLIANLGEHILFTASKSCAIMSTHIVACLLLYRHRQGIHLSTLVEDFFVMKEEVLARDFDLGFSGNSEDVVMHAIQLLGNCVTITHTSRKDEFFITPSTTVPSVFELNFYSNGVLHVFIMEAIIACSLYAVLNKRGSGASAGGPGSFISQEQLVRKAASLCYLLSNEGTISLPCQTFHQVCHETVGKFIQYGVLTVAEQDDQEDVSPGLAEQHWDKKLPEPLNWRSDEEDEDSDFGEEQRDCYLKVSQSKEHQQFITFLQRLLGPLLEAYSSAAIFVHNFSGPVPETEYLQKLHRYLITRTERNVAVYAESATYCLVKNAVKMFKDIGVFKETKRKRVSVLELSGTFLPQCNRQKLLEYILSFVVL", "length": 827 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8D1BQI2-1", "protein_name": "Uncharacterized protein", "gene_name": "LCE5A", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSCQQNQQQCQPPPKSLPKYSTPKFPGPCPPLVSSCCGSRSGHGRCYSSGGGGCCLSHHRRRRYHPCQPQSSNCCDSGGGQQSGGSGCSHSSGGSGCCSGGCC", "length": 103 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8D1VKI8-1", "protein_name": "Uncharacterized protein", "gene_name": "NCR3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MARMLLLILIRVHSGSCALWVSQPPEICTQEGTPAFLPVPSTPARGDWPLALSHGTGTNWPQGRRVVVLGQGVRTGNGTPLVVERGPAQLATPTIFLLRAGFYAFGFLSVAIGSTIYYQGKCHRHMGTHCRSADGL", "length": 136 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8I5XVN6-1", "protein_name": "SPATA31 domain-containing protein", "gene_name": "LOC689526", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MESFLLLMNSAIESWMNTSTMDIATDLSIAILCGVGLFFLLIPFLKDCPLSPASGNKTDIPKDVKRGRSNTRRKTDVEKGCRDGGKTVEETKTPSQPMKILTRQLLQDSTPQIFWNSSQKLDHLLLSQLFSSLTSLEDLILQKFNRRFWGTSSIFSESVVAMAHVLRNPSFPQQKSVRFSDPCVTDQAPSQAQGLRQQHRYHPRLHRQRKTSLVGMTWVPEKKILPISTPKQIHPCLKRRAYGVSCPTTEKGIQTSLPPECLSHKHGLYSKAVKGYVKRNHQKAIGKPPGNWLRDTLKTKAIRPASILSEHLRMFLHHKEPQTKDKATNVEKQQGTCIRSPPSKKLKQFQGRFPPNTDHYCKRRPQLSQPGQPSILNSKSYKLRKIIQSVLAGMTLMKDRADFSMQSQFSQAPQSSVCNAKRYKYSKRMGSVPRRVPLKKDTARYDMGKPIKKCLGAGTKNVPHSACSILGKRLRARNLALKKGQASVMNPTGNYCLHDSKAEMKLASNNTALPVQCRRTPYLQILEALNPIPPGVLASKLPRIVFPSSPICDFKEEYYSKAATVLKNLHHQDPGGTRVKSTSAASLESALSMCSAAKIQKTQRAPPPAASRGLSKAHTDLLKRHLSIQHSALYFEQGRIIQGTGKGSLQQNTNPQKAKHAPLKSFHEGDSRHHSWNGTMVGPGKRVPPAAAKQTKAVEVKKETPYAWSLGSNESHTGKDINISPRVFGSLGAKRSPGHLQTCTPQHSQDSTLRTQGHRNIILCSNKQPQPRPGRHDPECPSTVHPAKVNLSSEHSMSSFQNTCQKPKTAQGSCERADTKENRVLKDKIRINHLKDLCPHKERQGSIRPTAISQGGRLGRSRPCSLSSTQLKDTAKTRTSDKRQATSKSSWKSDIREVLKYGYVGSKDIIGQEDTSKKDQPPAVTERTEEDWTGEKAMCNMIAHLQYLTNFLFEIMEDTEWDPSKLQGCEVESLTFQLGSSSDSSEGDDDINQGTSTSTMSFGQTSPEMHNCSFTKTGIGDKTQSEIKAKTACDQHLNQVNRGMFSDQLPMPKEYDLSCRYRGIQHQQELGLPDQTFYQYKLRMTHCPHGGTKGHNYSFGYRKLGDQQQPDFTHKALDPHQSAKEDMGCVSCLSPKGSRPVKHRRTDCFSP", "length": 1151 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5XWP3-1", "protein_name": "Ig-like domain-containing protein", "gene_name": "ENSRNOG00000063695", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQRDMCHMTPYRLLCVLVALALSGCNVAQEVTQVQSTASRQEGEEVTLDCSYETSYVAYYLSWYKQHLSGDIIFLIHQISSSTAEERSGRYSLVFQKSLKSISLVISASQPEDSGKYFCALSDLTQC", "length": 127 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5Y4M0-1", "protein_name": "Large ribosomal subunit protein uL14", "gene_name": "LOC108350588", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSEQRRGGSSGAKFRISLGLQVGAVINRADSTGTKNVYIISVKEIKGRLDRLPAAGVGHMVMATVQKSRPQLRKKVHPAMVIRQQKSCGRKDGVSLYFEEDAEVIVNNKGKMKGSAITGPIAKEHADSWPRIASNAGSTA", "length": 140 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5Y5C9-1", "protein_name": "Ribosomal protein L32 like 2", "gene_name": "Rpl32l2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAALRPLMKPKIIQKRTKKFIRHQSDRYVKIKRNWRKPRGINNRVRRRFKGQILVPNIGYGNNKKTKHMLPSCFRKFLVHNVKELEVLLMCSKSYCAEIAHNVSSKNRKAILERAAQLAIRVTNPNDRLCSKENE", "length": 135 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5Y6V7-1", "protein_name": "UPAR/Ly6 domain-containing protein", "gene_name": "Pate4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRNTEPLFDIVINCPIAPQFILKILLFPYPANTNLICNTCNRSENSECKNGTGQCTAPEGGSCSTISIYHGQRHVLSKQMCLGHCEEKPHYNGDFMIYVMCCSKNLCNSF", "length": 110 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5Y7P1-1", "protein_name": "Heterogeneous nuclear ribonucleoproteins A2/B1", "gene_name": "ENSRNOG00000069815", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEREKEQFCKLFLGGLSFETTGESLRNYYERWGKLTDCVVMRDPASKRSRGFGFVTFSSMARPHSIDGRVVEPKRAVAREESGDPGAHVTVKKLFVVGIKEDTEVHHFRDYFEEYGKIDTTEIITDRQSGKKRGFGFVTFDDHDPVDKIVLQKYHTINGHNAEVRKALSGQEMQKAQSSRSGRGGNFGFGNSRDGGGNFGPGQGSNFRRGSGGWESSDGYGSGRGFGDGYNGYGGGTGGGNFGGSPGYGEGRGGYGGGGPGYGNQDGSYRGGYDNYGGGNYGKGNYNDFGNHNQQPSNCGPMKSGNFGGSRNMGGPRDEHRSFPSWKGYNGVFGKQSPLTWIKTHSL", "length": 347 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZKP8-1", "protein_name": "Glycerol-3-phosphate dehydrogenase [NAD(+)]", "gene_name": "Gpd1l2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGATTLRVCIVGFWSWGSAIAKIIGTNVKNQQKFASTVKMWVSEEAVNGRKLTDIINHYHENVKYLPGHKLPENVVAVANLSEAVQDADLLVFTTPHQFIHKICNEITGRVPKKALGIIHMESIDEGPRGLMLISDIIREKIGMDVSVLMGANTAREVAAGEFCETTIGSKVIQNGILFKELLQTSNFCITVVDDADAVELCGALKHIVAMGTNFCNGLHCGNNSKAAVLRLGLVEMITFTRIFCKSQVSTTTFLESCGFANPITICYRGSDCKEAKTFPRIGKTMGNLQKEVLNGQTLQGLKTSALVYQFLKQKGLLAKFPLFVTVYRICYEGRPSTEILTCLQNHPAHM", "length": 351 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZL63-1", "protein_name": "Ankyrin repeat domain 13a", "gene_name": "Ankrd13a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVSDQSRKAAAEGGSSPMVWSRPARAPPGGRADGRGPIVERTTGEGRAGDESRRARTVGFVRGDLGLPKGPAVPQNGGGRVSRRGGLVGRHGAGLGPFRKSGPPPRSVMERLAYFPVRGGSAGSSRFASCQRGRERAGRGVGAAERVPEPVPSPARDPGPPAPPAPDSEALVVRCARHLAARRSPPLALRPVGRAPETPSGGSRLVAGGRSGLGGDLLAMSSARDTSSRFPLHLLVWNNDYRQLEKELRDQNAEALDPRGRTLLHLAVSLGHLESARVLLRHKADVTKENGQGWTVLHEAVSTGDPEMVYTVLQHRDYHNTSMALEGVPELLHKILEAPDFYVQMKWEFTSWVPLVSRICPNDVCRIWKSGAKLRVDITLLGFENMSWIRGRRSLIFKGGDNWAELMEVNHDDRVVTTEHFDLSQEMERLTLDLMKPKSREVERRLTSPVINTSLDTKNVAFERTKSGFWGWRTDKAEVVNGYEAKVYSVNNVSVITKIRTEHLTEEEKKRYKEDRNPLESLLGTVEHQFGAQGQDLTTECATVNNPTAITPDEYFDEDFDLKDRDIGRPKELTIRTQKFKATLWMCEEFPLSLVEQVIPIIDLMARTSAHFARLRDFIKLDFPPGFPVKIEIPLFHVLNARITFGNVNGCSTAEERQSVEGTQAECAASDATNFEVDQSVFEIPESYHVQDNGRNVHLQDEDYEIMQFAIQQSLLESSRSQDLSGPASNGGVSHAHSYEAQYERAIQESLLTNMEGRCPGGLSDSSRFDSDLRLAMELSAKELAEQELRLQEEEAELQQVLQLSLTEK", "length": 809 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZP24-1", "protein_name": "Large ribosomal subunit protein uL30", "gene_name": "ENSRNOG00000064315", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEAVPEKEKKVAAVPGTLKKKKVPAVPETLKKKRRNFSELKVRRLRKKFALKTLRKARRKLICEKAKHYHKECRQMYLTEIRMARMARKAGNVYVSAEPTLAFVIRIRGISGVSPKVREVLQLLRLRQILNGTFVKLSKASVKMLRIVEPYIAWGYPNLKSVNELIYKRGYGKIRKKRIALTDNSLMARSLGKFGIICMEDLIHEIYTVGKHFKEANNFLWPLKLSSPRGGMKKKTTHFVEGGDAGNRETR", "length": 251 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZPV0-1", "protein_name": "ATP synthase peripheral stalk subunit F6, mitochondrial", "gene_name": "ENSRNOG00000066253", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MIVQRIFRLSSVLPSAVSVHLRSNPGVTAVAFNKEPDPVQKLFVDKIREYKTKRQVSGGPVDTGPEYHQDLDREPFKLKQLYGKGEMDKFPTFKFEDPKFVVIDKPQS", "length": 108 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZRI3-1", "protein_name": "Natural killer cell cytotoxicity receptor 3 ligand 1", "gene_name": "Ncr3lg1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASQSCQRGPENAHMHPKGPCCSALCFLCSLGSSPHGSSLGPLRKCGRRSKPVQSSPEGSRVAEWPDGLLSLLLLLWSLLPSAGGLELEMAGTTQIVFLHEDVTIPCKILGSLHLDLSIVGVIWSLKKDGDESEVFKFYGDQLEAVRPGANVSLLGLEHGDASLYLPRFELWEAGEYQCKVVVTPEKKEGTTRLEVVAHPNMSLSEKPATARGGKEKLIICQLDGFYPEALDIKWMGSALKDSHFQEITEGVVTGPTVKNDDGTFSVTSSLALKPALEDHMYQCVVWHRSWLMPQSLNVTVFENTRDSTHGTVPPTAEVGPPVSEPRSVMIYVTIIGLCILLFSVIVCGLWKWKRLTTSNTGLCLRLDVRC", "length": 371 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZS91-1", "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "LOC134482834", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPTETEEELPTPTPKPSISEEGNFHSQYQVLGTSGQGGNGKVLLAHNRLTGTPVAVKVLRKDKQWFQPAMMEANIMRKINHPNIVSLIQVIEKETRIYLIMELVEGQELYQYIRESGHIEEDEARQIFEQILSAVSYCHGKGIVHRDLKLDNIMIDKNKKVKVIDFGLSTQFPPGKMLNHHCGTHSFGSSELLLGHRYDRPKNDMWIIGVVLYCMVVGKLTFDSVIIQDLQRQVVAGVYPAPCGVSKELEDLLSKLLRVNPNFRPTARKAMKHPWFKEHWNGLIVPYEELLPLTPDPAILDAMKSIGLQASVVKHTLKQRKYNEEMATYFFLQKQALQGDGCTAQAQQVSPVAAPFPSLDPAAAFRLEPKRSGSLPVLGTLRVSSSHGHVSHYGQNAHPKGGKRYTVAGRLRPLPMTPTQDHYHKCAVSVPCIQTTSIFSEKSSNKKIKEDNPLSHRAPLEDKPIPSRVRHRGFKGWTRNIANALIKLCCCMPRRKKPRLGQNRISPQK", "length": 509 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZT61-1", "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "LOC134479845", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDITSIKKTLGSQYRVAFFLGQGSYGSVKLAWHRRTQALVAIKTVEISKNTIRAILSEMTTLELLHHPNIISLFQILVTANQIHFILQYAPGGNLVQLISEEGPLPEEKAKKMFGQIVSAIRHCHSLDIVHRDIKPQNILIDGEGNVKLIDFGLAVKCRPGTLLSRHCGTRGFNAPELVLRQPYDGKSSDVWSLGVLLYFITTGYFPFRGNTIDEIEQKITTGTYTVPHHLSGQLENLIHQIFTVSPEMRPSIEEIENHPWIKKCELKIPPMSDPDYKIIEMLCGMGYNAKDILESLQKKRYDEPMGAYLSLKNHVSEGYDLASITPTKPGDPCPPPPPSPAHPSVFGLPLRRRASEPNFGLLHRQPSREQNPLDLILSGLNMGRCVSMPPIAVYYPKKQRSTSTRALHSRPVASPCVYNNMLGVEIILPHKQDIEMNTSSPPQTMGWFKRLRKGIGDCFSRLCCFPRAPKKKTQHRSSKRVAPLKKAASSTI", "length": 493 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZXB5-1", "protein_name": "Uncharacterized protein", "gene_name": "Pilrb2l2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "TALLSSLPGRNLAMARLLLLLLSAACLHTGNSAGYQEKNDFGVDQPDVLSGVQGGSIEIPFSFYFPWKLAKDPQMSIAWRWKHYHGEFIYTSTRPFIHEHFKGRLIMNWTPGQTSGVLRILNLKENDQATYFSSVFLQTPEGMKLWQSIPGTKLIIHALDTTMRSPSIIPSVVPTDDLEYTQGQRNPSLLNLGAMVGMVMAKVVVIIPLYGWMIFLWWKQR", "length": 221 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZY57-1", "protein_name": "40S ribosomal protein S26", "gene_name": "LOC134478821", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSPGPRRPRQEAGSKPRELQQRVLASVKRRCLFSSLGSNTTKKKRNNGRAKKGHGHVQPIRCTNCARCVPKDKAIKMFVIRNILEAAAVRGISEANVFDAYVPPKLYLKLHYCVSCAIHSKVVGNRSCEARKDQTPPPRFRPSGAAPQPPPKPM", "length": 154 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZYE5-1", "protein_name": "Oligosaccharyltransferase complex subunit", "gene_name": "Ostcl1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "METKHSALLRTFPFLVLECPNLKLKKPPWVHMLLAMTMYALVVVSYFFITGGIIYDVSIEPPSVDSMTDEHGHQRPVAFLARRVNGQYIMEGLASSFLFTMGGLGFIILDRSNTPNIPKLSGFLLLFDFVCVLLSFFIARVFMRMKLPDCLMG", "length": 153 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZYN2-1", "protein_name": "Non-selective voltage-gated ion channel VDAC2", "gene_name": "AABR07051831.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAECCVLVCPRPMCIPPPYADLGKAARDIFNKGFGLGLVKLDVKTMSCSGGEFSISGSSNTDTGKVSGTLETKYKWCGYALTFTEKWNTNNTLGTEIAIENQICQGLKLTFDTMFSPNTGKKSGKIKSAYKRECINLGYDVDFDFDFGWLAGYQMTFDSAKSKLTRNNFAVCYRTGDFQLHTNVNNGTEFGGSIYQKVLCEDFDTSVNLAWTSGTNCTRFDIIAKYQLDPTASISAKVNNSSLIGVGYAQTLRPGVKLTPSALVYGKSFNAGGHKLGLDLELEV", "length": 284 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZYX3-1", "protein_name": "Methyl-CpG binding domain protein 3 like 3", "gene_name": "Mbd3l3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "LGELGNAGRLTGSMIPSRLQKRRKIQVAKSKRKAKHKSGTTLRNPLRLTSCIFPQPVTVITSYPENKTRYRRDEAKLKKPQQLCALERLKNFQFGGDSKENLSCPLELANAVERIARGMQDEASNQSGDKDQLTSGQVTSDQPPYLETNEHVALQLSPSFSSQGVTLPVPLHLSPSYFLRKVTTGDIQRQAWKVKKARKRLAEALEADRLARQTENMRE", "length": 219 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZZU9-1", "protein_name": "Keratin-associated protein", "gene_name": "ENSRNOG00000070302", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "SPSTCELSSSLHSDCQETCIEPSICQRSCVASSPCQMPCYYPRSSTACSPCQGTYDGSMGVGSNSLKSFGGFTGSLGYGNSGFGSFGFGSCGIRSQGFGCNFHRPGYFSSKSVQSSYYQPGYTSGFC", "length": 127 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZZY5-1", "protein_name": "Ribosomal protein eL8/eL30/eS12/Gadd45 domain-containing protein", "gene_name": "ENSRNOG00000064452", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTKIKAVTEESEAQGEGCSQQHRYQELLVYLNPIAQHPGFPPPDLRKIEKGKKKKKRRPTKQKQIRHGVKEVQKFVNKGKKGIMVLTGDTLRGTAIFQLCARTRICPTSIFPLTDLGAAMGSKHPTCVIMVKLHEEYHEAYDKCLEEVQTLATPL", "length": 155 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A2Z7-1", "protein_name": "Developmental pluripotency associated 1, pseudogene 1", "gene_name": "Dppa1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MMPPQVLISGLLLLLPAAWTTTVTSSDQLWNNHTEVVPTQSPLKISTKDLYIGTSVSAALLILLAGVLAVLKYRHRRKKILESAVVFHGFQNGVFQSTEQSQAVDVYVIEDSKVPVAH", "length": 118 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A3D9-1", "protein_name": "Small nuclear ribonucleoprotein Sm D3", "gene_name": "Snrpd3l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSIGRPIEVLQEAQGYMVTRETITGEVYPGKLIEAEDNMNCQMSNITVTYRDGPVAQPEQVYICDTKIRFPILPNMLKNAPVLENLKNKNQGSRAGQGKAAILKAQVAARGRGHEMGPWKLPEAKTVFSIKENFPSCLLLGF", "length": 142 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A3N0-1", "protein_name": "Uncharacterized protein", "gene_name": "Pramef20-ps2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTVQTPPTLEKLAIQSLIRNEDVAMSSLGELPAVLFPALFKEAFTGKHINLVKEVVAAWPFPCLLVGALMKTPNLETLQAVLDGVDMQLTRKFHTRRTKLQVLDLRNMHHYFWNIQAGEEDSSCSAENSKEKKVVKVFHRYALRKRVKVIVELYIHSCLKEEQTCLLKWAQQRKGSLHFCCTKMKVWNLSLCGIGEILKVFDPQHITELELHTEWTLLELAHFAPYFGQMRNLQKAFLAPLHRIMFSNSNGKRDREAKCIKKFISQFSKFNCLQHLHMFCVHFLRDHMNQVLGCLMTPLTLSITYYLISQKDLDSLSRSQSLFQLKHLDLRGVVLCDLDIMPLRGLLEKVADTLETLDLQWCKMTDSQLYALLPALRHCCQLTMVNFYSNNFSVPILKDLMQHIANWSRIRVQQYPAPLECYDDLAQVSVKRFAKLSSELMYTLGVIRQTKNISFATDICHTCGQRCVYHNGSRLCCCWH", "length": 480 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A3R7-1", "protein_name": "Ubiquinol-cytochrome-c reductase complex assembly factor 3", "gene_name": "LOC120093241", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEAARKALTVVAVLGSGAGVGSILFALVTPGELQKQLMLQEMPERDSRRRDAAVRTKELVMATLKDAAATKENVAWRRNWTVRGDGRSA", "length": 89 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A3T5-1", "protein_name": "Large ribosomal subunit protein mL62", "gene_name": "Mrpl58", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "EHGGRLGPTLEPEPSWNLVAPAARALCSPDSAQTGERHRVQEHLQPGQAVPRIQGRGYRLEGPGEPRKAGRKGRFLLLLDRLSISYCRSSGPGGQNVNKVNSKAEVRFHLASADWIAEPVRQKIALTHKNKINKAGELVLTSESSRYQFRNLAECLQKIRDMIAKASQVPKEPSKEDAQLQRLRIEKMNRERLRQKRINSTIKTSRRMTMD", "length": 211 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A478-1", "protein_name": "T-cell activation Rho GTPase-activating protein", "gene_name": "LOC134485907", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGEIHRTLLCQGPVELTSGRKRNKRYLSLFDDVLVVSTNLTKKKFKIKCIIPLNYLWVVDDVELVRANQTCTCKTIFFYWATGNALATFRSKEQKVQWYTFLTRSINEAKKGIKKTFPLHIFPEDIQTCDSSLCVTATNMDTVNDIMEKLLPMIRVHNIEDYQLWFSPGHKETPRALQGHEYPYDIIMNNVQNNLSKSNSKIFTAFPPLPGLFMENQSWDTGGQFILKPRDSAGSQQQDAKERPRKSCMTSCFHGGSVPHHDQECSDPRDDKRGKLFGQDLSSICQDGKLPTIILDMLSRIKDKGPTTDDIFLITPNGSLCKTIKEKLDNGENVDIYQQPVHVVAWILKEFLQSIKGSLLTSKLYDQWLIVPEKVNDKEKLAAVKSLLEKLPKPNADLLRQLFRILHQIKTNSSVNNMSSFRLSLETAPCILWLPSYRNNILTNDIAKKISLVTFMIDNSPELFGEDIVAVWYETSLYHPPGLKYPCSQNTPSSNGIMEETEHGLSSCPGERTCTPDFDELPRSGAAASIPYEGILASEKGEGNESTTQPEPVQNSPTPQTKKELGNCSPNILKDVNVPAVILDMLSVIAEKGQCSDDIFRMQSEKSHWSLKEKVNTGKHVNLKEESVLTVASVVKDFIKNIEGSLLSCDLYENWLSIPDEGPLLGKIASIQNILLKMPKPNYVLLKQLICVLQKIKAASTNQLDTFDLSVRIAPHVLWNPTCKTLFGRDLSKKLSIIKFMIDNCQELFGENDNIFCEDNQKSYDINLSSDTLNTSGKATLMIETIDDHDVKTSKSNTKKLEMSSAVPHEGGPTAGHNGTTSKYNVPQEKILHD", "length": 834 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A4C1-1", "protein_name": "RRM domain-containing protein", "gene_name": "ENSRNOG00000063783", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "LTCCAINSDPHPDSGLKMEGHDPKEPEQLRKLFIGGLSFEATDDSLREHFEKWGTLTDCVVMRDPQTKRSRSFSFVTYSCVKEVDAAMCAQPHNVDGRVVEPKRAVSREDSVKPGAHLTVKKIFVGGIKEDTEEYNLRDYFEKYGKIKTMEVMEDRLIDKIVVQKYHTINGHNCEVKKALSKQEMQSAGSQRGRGGGSGNFMGRGGNFGRGGNFDGRGGYGGGGGGSRGSYVGGDGGYNGFGGDSGNYGGGPGYSSRGGYGGGGPGYGNQGGGYGGGGGGYDSYNEGGNFGGGNYGGGGNYNDFGNYSGQQQSNYGRMKRGRFGGRSSGSPYGGGYGSGGGSGGYGSRKF", "length": 350 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A5E5-1", "protein_name": "Paired immunoglobulin-like type 2 receptor alpha", "gene_name": "Pilrb1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAQILLLLLSATCLHTGNSGGYTRKNYFGVNQPAVLSGVQGGSIEIPFSFYFPWKLAKDPQMSIAWRWKEVHGEFIYQSTLSFIHEHFKDRLILNWTQGQTFGVLRILNLKENDQATYFSQVCLQTTEGMKCWQSIPGTKLIVTHGVICSLLISPQLSYDHEDPLHHHLCRPHSWPGEHKGPKESFTAEPGGHHWDGRGQSCSHHPPLRMDDLSVVEAKASRVTPKPQPE", "length": 230 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A5T5-1", "protein_name": "Large ribosomal subunit protein eL21", "gene_name": "Rpl21l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTNTKGKRRGTRYMFSRPFRNHGVIPLATYIRIYKKGDIVDIKGMGTAQKGMPHKCYHGKTGRAYNVTQHAVGIIVNKQVKGKIPAKRINVRIEHTKHSKSRDGFLKRVKENDQKKKEAKEKGTWVQLKRQPVPPREAHFVRTNGKEPELLERSPYEFMA", "length": 160 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A8T3-1", "protein_name": "Olfactory receptor", "gene_name": "Or1o11b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "RMNCSQAPGFILLGLSRDPEKWQLFFSVFLVLYLLGLSGNLLLLLAIGADVHLHTPMYFFLSQLSLVDLCFITTTAPKILQTLWTGDGSISFSGCLTQLYFFAVFADMDNLLLAVMAIDRYAAICHPLLYPLLMTPCRCGVLVSGSWGVAHCVSLTHTLLLSQLYFHTNQMIPHFFCDFGPLLLLSCSDAHLNEGLMMALAGVFGISALLCIVSSYSCIFYAVARVPSAQGKRKALATCSSHLSVVLLFYSTVFTTYLKPPSSSYSSGEVVAAVMYTLVTPTLNPFIYSLRNKDVKSSLRRILNMVKSPD", "length": 310 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A969-1", "protein_name": "Uncharacterized protein", "gene_name": "ENSRNOG00000067430", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFFLFWTFPGLELDKLALLSFESSSSIHPRACASTPAFQRSHNPGDAAQQEAKQREAEMRNSILTRVLDQSAWVRLSDLALVKPDKTKAVEHRVQMARYGQLSGTVSEQGFIETPEKVSQQTEEKATVKFNRREVTDSDEDDDY", "length": 144 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A9H4-1", "protein_name": "NAD(P)(+)--arginine ADP-ribosyltransferase", "gene_name": "Art3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGQATARGVIKRKAFPGRQLSLSTTSCPGGKITPAESGNRFESGHHLNVLQRHKRQKRKMKMGHFELVTTLLAAMVLMDVFQVQAEVLDMAENVFDDEYLKCNSRMEMKYIPRMHGEELANDELLQSVWDKAGIQWEAQKAQLSLPKNFKDAYGIALTAYVTEAQDQSPFYHTFNRAVKIAGLSRRRYIYNFPFKAFHFYLVRALQLLRRPCEESYKNVVYSTSPNISFAFGEQNQARLGNFTLAYSAKPQTANEQRLLTIQTCFGVAVGKLLNKESEGIVLIPLSEVFQVSRKGTDDDLILHSINSTCSYYECSFLGGLKAGSCTTNPENPDPGYLNNPDLDSQKLEDSGRKSLDSVKMPEIKVLQGEENPLLPDEKPEDRNRGKANVPTPGLVPVPGPKSHPSSSSGHRLLPSDTASTILLIAAAVDFIAL", "length": 433 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AA84-1", "protein_name": "Ankyrin repeat domain 10", "gene_name": "Ankrd10", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSAGAGAGVEAGFSSEELLSLRFPLHRACRDGDLVALCSLLPHTPRAHLAAEDSFYGWTPVHWAAHFGKVGAGTLRRHFPRGVLLGSERTPPCLESAATARSAPPAPPEGSRAHVQQSGLGVKGWGRGGAEAALAPPGVQGACAAARSPGPRGARGVMGGGAEMGSVWPAPRRTQGACAHLWLFRAGRADRMQLRRFARRPSGFGEWCGRLLLEARREPGASRSCLMETGRRAPLRHKGMDAALAAGGVRSAPAVVDGGLAARPTGPLSQLGPPCLECLIQLVRAGASLNVSTTRYAQTPAHIAAFGGHPQCLVWLIQAGANINKPDCEGETPIHKAARSGSLECISALVGNGAQTDLRNASGLTAADIAQTQGFQECTQFLLSLQNHQMSRFCPNGTLSGGHENILPNHINLGTNRKRCLEDSESLGVKKARTRVPSLDHTMPLANGDAEDDADRMHVDREFAAVSDMKNSSSVLNTLTNGSVINGHLDFPCVAQLNGMESRSDPCLTGSNGISNGQPFPSGQGPVCANGTEEPEKTMGVNPEMCGSLHLNGSPSSCVASRPSWVGDIGESLHYGHYHGFGDTAESIPELSSVLEHSSCVRVEQRYDSAVLGAMQLHHGS", "length": 621 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6ABF4-1", "protein_name": "Nuclear transport factor 2", "gene_name": "AABR07018058.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGDKPIWEQIGSSFIQNYYPLFDNDRTQLGAIYIGASCLTWEGQQFQGKAAIVEKLSSLPFQKIQHSIMAQQYQPTPDSCIISMVVGQLKADEDPIMGFHQMFLLKNINDAWVCTNDMFRLALHNSS", "length": 127 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AC04-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vom1r38", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSMLSQNKTLKSIEEVALHVILLCQVGVGTVANFLLFIHNFSVILTNCQLTPIQVIVTNLAVASAFNLLLLAFPNNVTLFVPRKAPSDLSCKLWYFICLVARSTNLSSTCVLSTYQFVMLLPGNWSRVILKGRAPKIVNYSCYGCWIFSVLNNAYIPVKVSGPQKTQNDTDFKDKWVCSTSGFSVGMSFLRFAHDALFISIMIWTNVSMVILLNRHHHRLQHIHSSNQDHRAYADTRAAHTILMLVVTFLSFYLLDCICTFFHISFVDSRLLLRRIKEVLTASFPTISPFLLIFRGPKNPCSLLSRS", "length": 307 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AC51-1", "protein_name": "Non-histone chromosomal protein HMG-17", "gene_name": "Hmgn2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPKRKAEGDAKGDKAKVKDEPQRRSARLSAKPAPPKPEPKPKKAPAKKGEKVPKGKKGKADAGKDANNPAENGDAKTDQAQKADGAGDAK", "length": 90 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AC66-1", "protein_name": "Eukaryotic translation initiation factor 6", "gene_name": "Eif6-ps1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVVRASFENNCEVSCFARLTNTYSLVAIGGSENFYSVFEGELSDTIPVVHASIASCRIIGRGTSVWGTGMGYWYPTTTTDQELQHIHDSLLDSVQIRRVEEGLSALDNVTTCNDYVALVHPDLDRETEEILAGVLKVEVLTVADQVLVGSYCVFSNQGGLVYPKTSIEDQDELSSPLQVPLVAGTVNRGSEVIAAGMVVNDWCAFCGLDTTSTELSVVESVFKLNEAKPSTIATSMRDSLIDRLT", "length": 245 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6ACC5-1", "protein_name": "Uncharacterized protein", "gene_name": "ENSRNOG00000069094", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "LPLLAFEKYVVCDGELQRLQVSCEVLGDVDPPQRLSASVVQMKQSVVEFLGTLVEQDAQGAAEDMDNALVGDNEEAEGENNSTRTNSDGPFTERPNQRLNNR", "length": 102 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AEL7-1", "protein_name": "Protein phosphatase 4 regulatory subunit 3C like 1", "gene_name": "Ppp4r3cl1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEDKLYRVKVYVMMEDKQWKDIGAGQISSKYIDRLQGVCLLVHSESDGSPILECKIQPNVPYQKHQGKVIIWSEAKNHGTAIHFQEPNDCQETWEVICQVQGKDPNVEITQLLTDDLESFKDMLLSWNKVEMSSCELHTLENIADLLSFVNEAPSHKKILTLVLEKEGYIKKLLQLFKTCEKHQNIDGLHYLNNIIRGILFLDNIHLFNIMFSDEFIMDVVGCLEYGPGLDEPKQHRQFLTQNVKFKNVMQITHSQLRKKIQQTYRMQYIYDIVLPTPSIFEVNLLHDLSTMIFFNKIEIITMLQEDEHFLLEVLAQLKDNTVSNERRHELLLFFKEFCAFAKTLHFQKKNTLLKTLIKLGIISALKVVVHMHDYQIQVAALELFAHLVEYSPRLIRAYAMKEAQYSEDNDGLLINIMIKQMTCDSDPEFSRSIILTTVLHAILDPENMRVTTKGHERRKFLNYFYRHCMNKLIEPILSITVENNSDDNRVNICPDNYQNAQLLGAILEILTFCVQYHSKYVKNYIISKNLLSRILILMSSKHTFLILCAVRFMRKMIGLKDKMYNLYIVEKNLFEPVVNAFMHNGHRYNMLNSAIIELFEFIRQENIKSLIANIVEKFFMFFESIQYVQTFKGLKTKYEEEKKKKRERQLRKSLHNIIYQRIYCRHIKAMEVKVKADIFCRQITDKEEEREKGGGGGEGGGGRGGEGEGGREGGGREGEGGGGGKGGRGEGGAVLSMGSDIPSHYDMFVKINEMNERENVIECRKRKSSATSEYSTSCGDTSDNGISTVYCSSLVPLVDYAYDTDGEDDDGSYGNNENEEEEEEEEEEEPPKKKPYFHP", "length": 840 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AFG0-1", "protein_name": "Cytochrome b5", "gene_name": "ENSRNOG00000064959", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFAKEKGKFEDMAKDVKCYTLGEIQKHQDIKNSWAMLHHRVYDLTKFLEEHLGEEEVLRERAGGHASENFEDVGCSTNVQGLSKVHIIGLFHPALITTIKLNSNWWDQLCSPTSQVVVAHTFNPSTREVGAVGFP", "length": 135 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AGM4-1", "protein_name": "Proline rich 18", "gene_name": "Prr18", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLRLLGRVMSFSPMPPPPPPPPPPARTQGGPAARQLSRRPCGPPAASPPAPAAAAAGEKKRRPPEMLLSSSWPSATLKRPPARRGPGLGPGTPQPPTSARVPPQPSPGRGGTSATCSAPRRIACSHIPAGSTASGTSAGAGAGPEDATRFSLSLTPEAILVIQRRHLEKQLLARPRRPFPAPSADPRRPLVPCPRTRSSTLRRGGPTSVPDAPLAVAVSSRPPRASLLPGGLQATMPSPRPSSLRPVLKVSLLNEKHKYDDEEYEEEVEVVDEGLVRKCTEWLRGVESAAAARGRTGHLDSLPHLSTL", "length": 308 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AGS9-1", "protein_name": "Olfactory receptor", "gene_name": "Or5aq7b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEVWNSTGVKEFILIGLTENPNWQVPLFLLFCIIYFIILVGNCGMIFLIWLNVQLHTPMYFFLSNLSFCDICYSTIIAPKMIINFLSEHKSTRLFACILQSFFFAVYATTEVVLLSMMAYDRYVAIANPLMYTVIMTQSICTQMILASYLTGLINSLIHTIGLLKLNFCGPNIVNHFFCDVPPLLKLACSDSHINEILLLVFSGIIAISTLIIVIVSYIHIIIAILRIRSAMGRGKAFSTCASHLTAVALFYGSLTFSYIQPSSQYSMEQEKVSAVFYTLVIPMLNPLIYSLRNKDVKEAAQKLMLGKRNAC", "length": 312 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AIA3-1", "protein_name": "Uncharacterized protein", "gene_name": "ENSRNOG00000065493", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MIFVPFFPHPGSIRKDGVVYAHTMENSSNSPRETREPAPLRRTWRGCFQRALPRVSKFFRRGRGSTGGWDNGSPRQGPMHSDQDLRHLRSLLSKESCPVMSK", "length": 102 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AK52-1", "protein_name": "Olfactory receptor", "gene_name": "Or9s14", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAIEVHRNGSLSAMSLQGFVLLGFRGGAETQALLFTVFLVLYVVTVLGNLTMIMVITLDARLHSPMYFFLKNLSFVDLCLSTVVVPNALASIFFSSKTISFAGCATQFFFFSLLAATEAVLLAVMAYDRFMAICSPLRYPVTMCPMTCVRLVLGTFCVACLNSIVQTSLTFRLPFCSSNRIDHFYCDVPPLLQLACASTALNELVMFGICGFIIVCAVFVVIISYVYITVTILRMHSGSGRHKLFSTCGSHMTAVSLFYGTGFAVYGQPGGVASMEQGKVVSIIYILIIPMLNPLIYSLRNKDVKDALRRLGQRHSLAKESG", "length": 322 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AMC4-1", "protein_name": "Retinoic acid early-inducible protein 1 domain-containing protein", "gene_name": "ENSRNOG00000068014", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MCVFKNAWGHRNMCSMALCSQFGTHLHVSLTDAHSLSCNLIIRSPTKAEPLRYEGHCSMDEIVFLSFNNVNKTMPLGNQEKMANATKVQKCLTQWIDLLGQDLRDKVSEIKVHTTKTSGHPTLRVTMLSKHRHGEIIGASWEFNISENYSFILDLKTMKWKPQDIMKEWKDDETLMKHLNLSIVECSQKFNEFLNQHEERTSRYYLDSALPPAPPPLFKGFTILLWHSYTPAISPTSSDTHSSFINFRDGLIDINFPL", "length": 258 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AMN7-1", "protein_name": "60S ribosomal protein L7a", "gene_name": "ENSRNOG00000070681", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLKGKKAKGKKVAPAPAVVKKQEAKKVVNPLFEKRPKNFGIGQDIQPKRDLTRFVKWPGYITLQRQRAILYKRLKVPPAINQFTQALDRQTATQLLKLAHKYRPETKQEKKQRLLACAEKKAAGKGDVSTKRPPVLRAGVNTVTTLVENKKAQLVVIAHDVDPIELVVFLPALCRKMGVLYCIIKGKARLGRLVHRKTCTTVVFTQVNSEDKGALAKLVGAIRTNYNDRYNEIRRHWGGNVLGPKSVARIAKLEKAKAKELATKLG", "length": 266 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AMX9-1", "protein_name": "Ribosomal biogenesis factor", "gene_name": "Rbis", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAKNKLKGQKSRNVFHIASHKPLKAKNKAKPVTTNLKKINIMNHEKVNRMNRAFVNIQKELANFSKSLSLKSVQKELHHEKEPANVDEATRLMAQL", "length": 96 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6ARJ3-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "Or8b101l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTLGNVSSVKEFILLGLTQQPELQLPLFFLFLGIYVVSVVGNLGLIVLIVLNPHLHTPMYYFLFNLSFTDLCYSTVITPRMLVGFVKQNIISHAECMTQLFSFCFFVIDECYILTAMAYDRYAAICKPLLYQVTMSHQICLLMTVGVYMMGFVGAMAHTGSMLSLTFCEGNIINHYMCDIPPLQKLSCTSTSINELVVFTVVGVNVIIPTLTLFVSYTLILSNILSIHSAEGRSKAFSTCGSYIIAVSIFFGAVLFMYFKPSSASVDGDKVSTIFYTILGPMLNPFIYSIRNKDVHVALRRTLKKRIFT", "length": 309 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6ATM0-1", "protein_name": "ELAV-like protein", "gene_name": "Elavl3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKDAGAGSCRYKGLGAAAVRPRARSAQRGPVGGREGGREERTHYPAPDRPDRGPAAEGRAAEISVGKSDFCGPRGAALRAPSTARPLPPSTCRQGSGRRSAHPQARVSSRPSRAPPPPSSPLRRPQSQTPGRDPGVSTRRPPRSARPPEPPSIRTAPAGHTRMVTQILGAMESQVGGGPAGPALPNGPLLGTNGATDDSKTNLIVNYLPQNMTQDEFKSLFGSIGDIESCKLVRDKITGQSLGYGFVNYSDPNDADKAINTLNGLKLQTKTIKVSYARPSSASIRDANLYVSGLPKTMSQKEMEQLFSQYGRIITSRILLDQATGVSRGVGFIRFDKRIEAEEAIKGLNGQKPLGAAEPITVKFANNPSQKTGQALLTHLYQSSARRYAGPLHHQTQRFRLDNLLNMAYGVKRFSPIAIDGMSGLAGVGLSGGAAGAGWCIFVYNLSPEADESVLWQLFGPFGAVTNVKVIRDFTTNKCKGFGFVTMTNYDEAAMAIASLNGYRLGERVLQVSFKTSKQHKA", "length": 522 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AUS4-1", "protein_name": "Ubiquinol-cytochrome-c reductase complex assembly factor 3", "gene_name": "ENSRNOG00000062467", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQTAAGKTLAVVAVLGAGAGVGSILFALVTPGELQKQSMLQEMPERDSRRRNEAVRTKELVIATLKDAAATKGNVAWRRTGQLEGQGRMCGTKGTNKCSLPIKWISQLDI", "length": 110 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AWY6-1", "protein_name": "Uncharacterized protein", "gene_name": "ENSRNOG00000065059", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAKATKKSKNTTSDVEPSTSSAKSKKAKTCYQYQTRAGEKKSRWSGSDCSVNVQKTTKKAKRTLPRIAENNTSEKTVPPTKKTKRAKDEQLFGHYHRLMDEISTSTERGPEQSSTDSSSASTSDEESQ", "length": 128 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6B5G4-1", "protein_name": "protein-tyrosine-phosphatase", "gene_name": "Ptp4a1l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MARMNCPAPVEVTYKNMRFLITHNPTNATLNKFIEELKKYGVTTIVRVCKATHDTTLVEKESIHVLEWHFDDGAPPSNQIVDDWLSLVKIKFPEEPGCRIAVRCVAGLGRAPGLVALALIEGGMNYEDAVQFIRQKRRGAFNGQQRLPLEKYHPKMWLRFKDSNSHRNNCCIQ", "length": 173 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6B646-1", "protein_name": "Ankyrin repeat domain 66", "gene_name": "Ankrd66", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRSREARLHHQTPGDQEAGAACLLSWGGGGASFHGVNTLTLRPAMMACSTELLKDTDSVMELSKLSDMTKLHQAVAAGDYNSVKKILKKGLCDPNYKDVDWNDRTPLHWAAIRGQMEVIHLLIQYGARPCLVTDVGWTAAHFAAESGHLNVLKTLHALHAAIDAADFFGDTPKRIAQIYGQKDCVDFLDTAEPECRDHRQRGLLFDERDPDWDLKKRELELSLPVPDQNTNKKKKRIRGSTRVNHSKAWRI", "length": 251 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6G1V0-1", "protein_name": "Ankyrin repeat domain 62 like", "gene_name": "Ankrd62l", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSRVAGLSSKKSRWLLQSLLDQQRHSLGTGFESANILLSPKYHLKDKDLRKIHKAARDGDAARVQQLLLGKHCVNDKDKKKRTALHIACAYGHPKVVMALVEGKCEVNATDSEECTSLVKAVQCQEEECATILLENNADPNIVDAQGNSALHYAVYYKNTSLAAKLLDHEVNIEATNKDGFTPFLLAVSENKLKIAKFLLMKNASIHAADNQKRTALMHAVSHDSTNLVRFVLEQGVDLFVKDAFGLTAIDYAADFKYNSNMEILLEYKAKRYEESERANLVEKSSEEDSSRRKDQQSQELENMEKEELTEPGNGTEEQEPDGGVTSVEEPRRLDDRGDDQPQEAVTAPRTREKEQELPFTDMCTVVTGKEDEDESSWDSESVSENLPLIRIGVDGLLLVNGQAVENPEKYLHWLHNRKGEESVPNETKGVGDLQAFTPAEPGLELTSEEKHEELSRNEDCQPQVEEERTQEWSGWGAPEALCAAALDHGDIGSPLTRENGHPRARQSPSVDSEEQDGGSGLNIKEEKTRDHEEWSGDFLMDRTSKESEPAAGDLLQVKDSWSLNDTDPNKGSPAKRKSKEKHKVRGEMNAMEDADDFTPLSESCSDNKAELCCNTHQAETETESCELLTRQTGNMEGGVAGEVLKTEPARSREALKETEETGEGARVKMQLPGKDELYSEDAERQQYDMALSALHLKTKQTVRQLQETQDRQREVVRSSQRMQDHLQKLQAGCSEAEAMVQEQGKKTAELQKLHAGMIHELKEKWETIASKYLPLNIQLKYLEQELLSIKIAQKQYEKLHEDQRTLQRDAVDLQHQVQENMAKLDDEKQAMALRDSNNDSLMSQVELRIKNLESNLQKLQAEKESNERNVEKYLQRYIRERELSKTLSHTLHRTNSKLSRVRTDILLVTERNRTVQNTLTTRPVPKSPGVTEHSAYVNRNPNFIASRNLEAAMSSPQPSPELMRRRLLKKQKNMVKNITEEVDKAAAELESWSLEAYPSGSK", "length": 1003 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6G430-1", "protein_name": "Large ribosomal subunit protein eL24", "gene_name": "LOC689816", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLETCRNLSAIGYIWEDNSTEEYCKSSRRHGRPTSVTMKVNLCSFSGYKIYSGHERLYARTDGKFSSFLMPNVSPHSFPKGTLGKLTGLSSTEENTRKDSRKKFKRKEPTLQKFQRAITGASLADIMAKRNQKPEVRKAQQEQAIRDAKEAKKAKQASKKTAMAAAKAPTKAAPKQKIVKPVKVSAPRVGGKR", "length": 193 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6G808-1", "protein_name": "Paired immunoglobulin-like type 2 receptor beta", "gene_name": "Pilrb2l7", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MARILLLLLSAACLHTGNSAGYPKKYDYGVDQPAVLSGVQSGSIEIPFSFYFPWELAKDPQMRIAWRWKVFHGEFIYNSTQPFIHEHFKGRLIMNWTQGQTSGVLRILNLKENDQATYFSRVFLRTTEGMKSWQSIPGTQLIIHALITTPGSPSIIPSAVPTTGLEDTRGQRTPSLLNLGAMVGMVVSKVVVIIPLYGWVIFLWWKQRTQFRRDLVSEHPWKNFVPILPAESSSFL", "length": 236 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GB91-1", "protein_name": "Olfactory receptor", "gene_name": "Or4c117b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "TNRYYFNIFMIIMQNQSFVTEFILLGLSQNPNVENILCVVFLFIYLATIGGNMIIVVTIIYSPALLGSPMYFFLIFLSLLDACTSSTVTPKMIVDFFYERKTISFECCMTQLFAIHFFTGIEVIILSAMAYDRYVAICKPLHYSSIMTQRLCGILVIVSWAGGFLHSIIQIIFTLQLPFCGPNVIDHYLCDLFPLLKLACTEPHIFVILVFSNSGSISIIIFSILLVSYGIILFSLRAHSSEGRRKALSTCGSHITVVLLFFVPCFLIYARPTSAFSSEKNAFVFATIITPLLNPMVYTFRNKEMKNAIRKMWKRLIMVSCNY", "length": 323 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GF85-1", "protein_name": "Ceramide-1-phosphate transfer protein", "gene_name": "ENSRNOG00000064148", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "HFFLEYLNNLKIMLIFLSPPTGGWASDHHSPTTGTHLRFLNSLGAAFSFISKEVVSKLQIMEHPRSSPQSEHCSSLQSMAAYEVSNKLLDLARRSGPLHSNSGCRTVLCLHRALHWLQLFLEGLRTSSEDARTSTLCTEAYSAMLCAYHSWIRQAVTVAFCALPSGKVFLEMLGEALPFMEQMCDISQFYVEHFLLDLP", "length": 199 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GFV7-1", "protein_name": "Olfactory receptor", "gene_name": "Or1f21c", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSSTNQSSVTEFLLLGLSRQPQQQQLLFLLFLTMYLATVLGNLLIILAISTDARLHTPMYFFIMILSFTDVCFSSTTVPKVLANYMLRSQTISFSGCLTHLYFLCVFADMDNFLLAVMAYDRFVAICHPLHYTTKMTNKFCVLLIVGSWVLTNLNALLHTLLMAQLSFCGDNIIPHFFCDATPLLKLSCSDTHLNDLMILTEGTMIVVTPFFCILISYIHITCAVLRVSSPRGGWKAFSTCVSHLAVVCLFYGTIISLYFNPSSSHFAGKDMAGAIMYTVVTPMLNPFIYSLRNRNMKGVLRKVLILRFPSKQ", "length": 313 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GGC1-1", "protein_name": "Histocompatibility 60b like 1", "gene_name": "H60bl1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAKGATSKCNHSLTLSLLVLLNSLGTMQVDGTDSLSCNFTVQYKVSLGQCSVNGMTVLCFDDVRQNSPVCKTEKKGNATKLCNDLNQCLSYSFYEMMKLESGLFESKGNHTLRVTVQSQYNQGEFMDGCWAFMIDRQYPFYFYPKNMTWRENQPNAIKTMSQWENNRELFQSLKFLSTGDFSLCLKKLLTDSRELTRSTIKAPDTTQPTSTTQSPSTGNSTPAMSSNQSPSTGNSTQPTSTTDYLIVFEFTAIFLALIVVSMEKKKVLPAAPLPLQYELQSPSPAVLEES", "length": 290 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GIM2-1", "protein_name": "Olfactory receptor", "gene_name": "Or4x11c", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MADLFNVTEFIFLGLSPNKEVQRVCFVLFLLLYMAIVLGNLLMVVTVAVSRNLGSPMYFFLSSLSFVEICYSSTTAPKLILDLLAEMKSISVWGCMTQLFFLHYFGGIEIFLLTVMAYDRYVAICKPLHYTSIMNRKVCIVLVGTAWTGGFVHSFAQIVLIFPLPFCGPNTIDHYFCDVLPLLKLACSDTFLIGLLIVANAGTLSVIIFVVLLASYVVILFHLRTLSAEGRRKALSTCGSHVTVVILFFGPCVFIYSRRSDTLPVDKMIAVFYTVITPLLNPLIYSLRSAEVKKAMKNLWFRTMKADEK", "length": 309 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GJN1-1", "protein_name": "Heterogeneous nuclear ribonucleoprotein A1", "gene_name": "Hnrnpa1-ps20", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "LSQSPPRNRTEQLWKLFIDGLSFETTDESLRSHFERWGTLTDCVVMRDPNTKRPRGFGFVTYTTVEEVDAAMNARPHKVDGRVVEPKRAVSREDSQRPGAHLTVKKIFVGSIKEDTEEHHLREYFEQYGKIEVIEIMTDRGSGQKRGFVFVTFDDHDSVDKIVIQKYHTVNGHNCEVRKALSKQEMASASSSQRGRNGSGNFGGRGGGFGGNDNFGRGGNFSGRGGFGGSRGGGGYGGSGDGYNGFGNDGSNFGGGGSYNDFGNYNNQSSNFGPMKGGNFGSRSSGSYGGGGQYFANPRNQGGYGGSSSSSSYGSGRRF", "length": 319 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GJR0-1", "protein_name": "Aspartate aminotransferase", "gene_name": "Got2-ps6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MALLHSRMATTFHPGLAAAASARASSWWTHVEMGPPDPILGVAEAFKRDTNSKKMNLGVCAYRDDNGKPYMIPSIRRQRPRLLEKIWTKNAYPSGDWLVFVRLLQRSEPVFCKDILSLAKMSFYPNHPGETTRPSSGMPACSYKVIDTMTHKTCGFDFSGALEDISRIPEQSVLLLHACAHNPMGVDPRPEKWKEMVSVVKKKSLFAFFDMAYQGFASGDGDKDAWAVQHFIEQGINVCLCQSYAKNMGLYGERVGSFTVVCKDEEEAKRVESQLKILIRPLYSSPPLNGARIAATILTSPDLRKQWLQEVKGMADRIISKRTQLISNLKKEGLFHNWQHITDQIGMFFYMIKDGRISVAGVTSGNVCYLTHAIHQVTK", "length": 379 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GL73-1", "protein_name": "Uncharacterized protein", "gene_name": "LOC134481331", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "TALLVSLPEQNLAMARILLLFLSAACLHTGNSSGYRRVNDFGVNQPAVLSGVQSGSIEIPFSFYFPWELANDRSMSIAWIWKYFHGEVIYNSTQPFLHEHFKGRLIMNWTQGQTSGVLRILNLKENDQARYFSRVFLRTTEGMKSWQSIPGTQLIIHALNTTMGSPSIIPSAVPTAGLEDKRGQRNPSLLNLGVMVGMVLAKVVVIIPLYGWMIFLWWKQR", "length": 221 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GLF3-1", "protein_name": "Heat shock protein 90 alpha family class B member 1, pseudogene 13", "gene_name": "Hsp90ab1-ps13", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPEEVHHGEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLWELISNASDALDKIRYESQTDPSKLDSGKELKIDIIPNPQERMLTLVDTGIGMTKADLINNLGTIAKSEDQTEYLEERRVKEVVEKHLQFIGYPITLYLEKEREKEISADEAEEEKREKEEEDKEDEEKPKIEDVGSDEEDESSKDKKKKTKTIKEKSIDQEELNKTKPIWTRNPDDITQEEYGEFYKSLTNAWEDHLAMTSLSGYVSRMKETQKPIYYISGESKEQVANSAFVERVWKRGFEVVNMTEPIDDYCVQQLKEFNGKSLVSVTKEGLELPEDEEEKKKMEESQTKFENLCKLMKEILDKKVEKVTIPSRLVSSPCCIVTSTCGWTANMERIMKARALRDNSTMEYVMAKKHLDINPDHPMVETLRQKAEADTNDKAVKDLVVLLFETALLSSGFSLEDPQTHSNCIYCMIKLGLGIDEDEVTAEELSAAVREEIPPWRVMRMPLAWKKWIKGSWEAPALCIVSLGLPQQP", "length": 518 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GM54-1", "protein_name": "MAGE domain-containing protein", "gene_name": "Mageb11l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPHDQKSKLHSRENSYQAGGGAQAYGDAEEIAEAAAEAAEESSAKSQSQPGAEYSRNHRAPPKAKPSAKLILSSSSSESDESSHEESEPSVQKDRPFLHQDLIERRVAILLQYLLHNYNLKQLTTKEEMLKVITKKYEKDFPEILRKASEKLEDAFAVEVREVSSSQPSYDLISKLKLPNNGRIRAGKGLPKTGFLMSILGIIFIQGNSASEEDIWKILKKKRIYPGKKHRVFGEPRKLMTQYLVKLKYLEYRQVAHSDPPRYEFLWGPQAHAETSKMKVLEYLAKINKTTPHAISALYQEALKDEKERAEVRDEDNTDTTDQSTEGSPEKSPTASTTPVDT", "length": 342 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8J8YII4-1", "protein_name": "Coiled-coil domain containing 188", "gene_name": "Ccdc188", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEGPEPLGPCGHSHTQHPPAPVSNNHGGCLNQPCQGFVRWPCLVPLQSTQSLESSRPFPAPGTGSGGPRMRGEAPGMFLSSEGEIPRQRAREPAGARQEEVEVEWDWPLHPGHEQGPPRQTAPPTSGPRPCPCPTLPPRGRATASSRQAPTQLQGGTLESAQQSFLQLEQENHSLKRQNQDLREQLGALLGPGQQFLPLCSEHSSCTALAWVSGNTRSRTHAAAPPAVHSLGPDPGALPQSPESARTRLLEDRAPVQLLRQQELCPGKESFVRQSQSELQQIRLSFERKKMAITEVWDGVAEVHMALNNQATGLLNLKKDIRGVLEQMEDIQLEILGERAQCRTQARKQQQMMEAAGLEAAAGCSAGLHSGLRVRGGPHTLRGAGATPAEPSQRLEAQGLTGSLLTPGGGRLPAFLEQKPSGPSKEARWLVLPQGLRGLTGPCLQHCGTWPLPEAAEKGGGRASPEGWACSWIYSHDTLCM", "length": 481 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8M9PVG7-1", "protein_name": "5-hydroxytryptamine receptor 7", "gene_name": "htr7a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MVLGDTNRTIIAKSHGETMKSLMAEERARETGASVETFNGIMISEVLVPRLFKIAHESGEVAVAAGSGSMDMKPSSSPILLEMMEVANGTRCAEQILSYGEVEKVLIGGVLTMLTLITICGNMLVVISVCFVKKLRQPSNYLIVSLALADLSVALAVMPFVSITDLIGGRWIFGKFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVRQNGWCMAKMVLSVWLLSASITLPPLFGWAQNVNDDRVCLISQDFGYTIYSTAVAFYIPMTVMLVMYYRIFRAAKLSAAKHTITGFPRVEQEEVEEDEVEEDGGDGAEEPTGVDCVTVAIKLQREVEECARLPRILRGVGRRCSDRRSISIFKREQKAAATLGIVVGAFTICWLPFFLLSTARPFICGTECSCIPLWVERTLLWLGYANSLINPFIYAFFNRDLRTTYRSLLSCRYRNINRRLSAAGMHEALRLVERPEVVVSG", "length": 479 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M9QGZ8-1", "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "pimr118", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLFTVLGVIALFLRERDTNNTEEEVQNDVPPVRNSDGQEIDDWCKEPSLLEPVSVHSEEPSLEEPVSAHSEEPSLEEPVSVHSEEPSLEEPVSVHSEEPSLVEPVSVHSEEPSLEEPVSVHSEEPSLEEPVSVHSEEPSLKEPVSVHSEEPSLVEPVSVHSEEPSLEEPVSVHSEEPSLEEPVSVHSEEPSLEEPVSVHSEEPSLEEPSLDLSFFSAESSWSEDLSSSFLTVESSWSDDLSSGFLTAESGCGDDEPLFVDSAEPEKLKEDKETQIIEINSHCYAIEAQLGEGGCGAVFSATRLEDGLQVAVKLSDFEEEKRFISVDGFEDPLPLEIALHFLANKGPKVKEIIELLDWKVEADRYFMVLEQPIPCMSLHEFLLDCEGIIPENKLRTIMYQTTVAAQTCCQRGVLHRDIKLENLLINPDTLEVKLIDFGCGDLLTEDSFQYFRGTREYFPPEFSSTGRYHGEPATVWSLGVVLFLLVFYRFPEQSDLPRMNNRRLRIKGLSRDCCDFFHGCLQLDPKDRLELQNLSSHKWIRTRTRRNDENCPNLTDGSSHSNHPITSN", "length": 567 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8V0WZU8-1", "protein_name": "Ig-like domain-containing protein", "gene_name": "CHIR6B2", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAPMVVNLILGWWLVAVSRAQKLPRPSLSLHPSQGASLGDNVTLRCHLPQPAAWVRLYRYQNPTYIEQKDNVQDMAEFSLTSIKQEDAVIYQCQYQGLAPAGTSQKSDPMELLVTDHRYPPPGISLSPKEHVEMGSNITIQCWNKDYGASFLLHKGGHSAPIQHQEPDYWGTATFTLFGVTPADSGTYRCSYRIGGCCLLFSPLGDNVTLEVIPRPAPPGVNGGPSRNLVAAVAGGCAAAIVIITVSFLLVALRRQMQRAERPGATPRSPEAVQFQVSPGDSEGLTYAQLQAVTPSTHPPTSSTTPEPPIIYAEVGTRGPR", "length": 321 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XEA0-1", "protein_name": "C-type lectin like 8, MHCY region", "gene_name": "YLEC8", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MQSVQIPILKHKVSTPAEGERLNHFSEHKAAPEPTAHQRRRIPTSSDPQLPEEDVQILLLESNTSTPAMGEGDQQETFSEHQAAPEPLGQSGGHQWGSWCHGMGRRRSCVQLIAVHAALGALILMLVVLVISTVCRRAPIPPFSAFGHACPNAWVGFQGKCYYFSKEENDWNSSREHCSAHGASLATIGSAEEMDFMMRFQGPANCWIGLHREEEDAQWTWSDGTAFTNWFELRGGGRCAYLNGDRISSSLCHLHKHWVCSRADHYVLWKQKVHPQ", "length": 276 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XED4-1", "protein_name": "C-type lectin like 18, MHCY region", "gene_name": "YLEC50", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MQSVQIPILKHKVSTPAEGERLNHFSEHKAAPEPTAHQRRRIPTSSDPQLPEEDVQILLLESNTSTPAMGEGDQQETFSEHQAAPEPLGQSGGHQWGSWCHGMGRRRSCVQLIAVHAALGALILMLVVLVISTVCRRAPIPPFSAFGHACPNAWVGFQGKCYYLSKEENDWNSSREHCSAHGASLATIGSAEEMDFMMRFQGPANCWIGLHREEEDAQWTWSDGTAFTNWFELRGGGRCAYLNGDRISSSLCHLHKHWVCSRADHYVLWKQKAHPQ", "length": 276 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XEJ6-1", "protein_name": "Sulfotransferase", "gene_name": "LOC769841", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MVCRAAAPNSHPSTMPVHYVTYKGIKFPPAYNSVHSLSFAHNEFLVRDDDVFNITYPKSGTVWMTEILSLIRSHGHPSWNQTVLNSDRMPWFSTRLGLEAALSYPSPRLLTCHLPRHIFPKSFSHSTAKVIYTLRDPRDVVVSYFYFCKMCNSYEDPVSFEQFLRDFLSGELPHGSWFEHVRGWMQMKDRENFFFITYEELKQDLQGSVRRLCHFLGQNLDDDAISSVVQNASFMAMRQNPMCSSILLPADIMDQTKGQFLRKGICGDWKNHFTVAQTETFNRIYLEKMRGLNVAFPWDRDQDPDLTEQ", "length": 309 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XGU1-1", "protein_name": "C-type lectin domain-containing protein", "gene_name": "YLEC62", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MQSVQIPILKHKVSTPAEGERLNHFSEHKAAPEPTAHQRRRIPTGSDPQLPEEDVHISVLESNTSTPAMGEGDQQETFLEHKAVTEPLGQSGEKPQWGSRCHGTGRRRSRVQLIAVHAAVGALILMLVVLVISTVCRRASIPPFSAFGHACPNAWVGFQGKCYYFSKEENDWNSSREHCNAHGASLATIGSAEEMDFMMRFQGPANCWIGLHREEEDAQWTWSDGTAFTNWFELRGGGRCAYLNGDRISSSLCHLHKHWVCSRADHYVLWKQKVHPQ", "length": 277 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XGW1-1", "protein_name": "NHL repeat-containing protein 3", "gene_name": "NHLRC3", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAAPAVLWRLQRLSAAERLEARLSGAVRKEPGRGEARQSEKKPHSPHCPLRCSYACPGRTPMTSESGRKALSHLGRQQQCLNKMAELRARLEAFPAPECLFKTLNPFMGFLRLFFAPQPLGGEQALFRAAQCAEASPRIPAPQAWAGRSRGCHGNAARPASMGRKQAVGPRLVMAGALLTLLGLLWGSQMLKAFDYFSSWKGDGEQQMYKLDISWPKIPEYFSGQTFCVAVDSLHGLVYVGQRGDDIPKVLVFSVEGYFLYSWNDTVEMPHGIFVLNTATDSSVWITDVGSGKYGHTVKQYSPSGKLLQVLGTPGNAGSSLNPLQFDQPAEIFVEESGEMYIVDGDGGMNNRLLKLSQDYKEIWLSGENGTGIGQFKIPHSVTVDPFGRVWVADRDNRRIQVFDKVTGEWLGAWSSCFLEDGPYSVRFTGNYKYLIVAHLNINRLAILAAPPVGEIGDCAIVSTIQLADETKPHLVDVDVKSGAIYIAEIGAQQVQRFVPLS", "length": 502 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XPN1-1", "protein_name": "Ig-like domain-containing protein", "gene_name": "CHIR2A13", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAPMAVALILGWWLVAASRAQQLPRPSLSLHPSQGVSLGDNVTLRCHLPRPAAWVWLYLEGRWSYAKYIDKKQDTTEFSFLSASHDQAGTYLCQYQVSESEDVSVTSDPVKLVLTDRSFPPPHISLHPEERVGTGTNVTICCWNKDYGATFLLHKDGRSDPIQRLVPDDVGAVSFTLFGVTPADSGTYRCSYHPKNYPFLSSPLGDSVTLEVTPTPAPPGAELVSRGNLVVAVVRGCAAALIFGLGVFFVIDARSLWIRRDESLGGEGI", "length": 269 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XPP6-1", "protein_name": "SUN domain-containing protein", "gene_name": "LOC776146", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MEQQGHGERGNWQTKVWKTVALVLVTVAVASFGVYCVGGLVEGIKTTAGVTARLVRRDGEIVSLDEELAKVQRQLHVLQWRARDITERALHEALRRTELPGFTGEAVQKIIHQVLEKLEESPFQMTNYASKTSGAAIVRSKTSPSWIGSGRVFWQSLPLVAYMRPPEVILEPDNHPGNCWPFPGSQGHVFIKLPVAVFPTAVTINHGVPAAAYHADSISSAPKDFAVYGLQEEDDETGTLLGEFIFMPGQAPGQTFQLKNEHSAFIKYVRLQVLSNWGHPEYTCVYQFRLHGDPAPDGDARGKLSA", "length": 306 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XQE0-1", "protein_name": "Ig-like domain-containing protein", "gene_name": "CHIR6A8", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MEPMAVNLILGWWLVAGSRAQQLPRPSLSLHPSRGVSLGNLVTLRCHLPRLAAWVWLYRGGGWSYKKGKKKEQDAAEFSFASTLREHAGRYRCQYRVYESAEVSVESDPVELVLTDVRYPPSSISLQPEQHVGTGTSVTIHCWNKDYGATFFLHKDGSSDPLQRQDSSGGGTATFTLFGVTPADSGTYRCSYRHWRYAFMSSPLGDSVMLEVTPTPAPPGAELVSRGNLVVAVVRGCAAVLIFALGVFFVIDARSLWIGRDESLGGKGI", "length": 269 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XTD2-1", "protein_name": "Coiled-coil domain containing 97", "gene_name": "CCDC97", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MKEDPKEAEGPTASKWIPIASNGNPTASKWIPIASNGDPTAPKWVPISSNGDPNWVPISSNRDPMASKWIPVSSDRDPTVTKENPPSSNETPAAEWDPKVPPEGRPVEEGDPKASPTEDPPAEPDPKASNCAPLSSHWAPEAAVWDPTSPHRDPTAEPQCSASPEQHRAAQRDPASPMEEDRYPATHGVRPATRADPAPYGDHPEAEEDPLPAAVEAMLAAVAASPVRVRSQQQGDPELTAAERRRDLRALFLRKPLVFLERFHGALQAEHLPCFAHLPPRYEVAFYCRQVRARRQQNPQTGLSRWPRRPGARTRLRNRRYAALRQLIAGGEYFSEEEMRAREPLLYEHYIGQYRDAETPPGTPPCPPHPGTPPGTTWAAALLRSVEEAAVQQRLQRQRLREGDSGEEDEDEDEAEEPHIPDAGELEVLREEFRSRMYQRFLDGEDRDFDYSQVDENPDMDNLDIESRDAEERYFDEEEPSAAPQLE", "length": 487 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0Y889-1", "protein_name": "Transmembrane protein 65", "gene_name": "TMEM65", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MSAWLGRAVLLLGRPGGPAAPSSSSRLCSLRGPPRCCCRRRLSSLRGGADGLLPARGAPPGRALGTHPKKEPMEALNTAQGARDFIYSLHSTERSCLLRELHRFESIAIAQDPIAARASCQQYGETWAHQEPSGACSSVHSQAYHQKEAVPSSNCPSTKYDRTHYLWPPLMAEAAGKPGRCPHCCAEGWSSEKLEVAPPSPGQLRHVFFHNALPFVGFGFLDNAIMIAAGTQIELSIGVVLGISTMAAAALGNLVSDLAGLGLAGYVEALASRLGLSIPDLTPKQADMWQTRLSAHLGKAIGVTVGCILGMFPLLFFGDEEEKLEEKN", "length": 328 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0YA34-1", "protein_name": "SWIM-type domain-containing protein", "gene_name": "LOC100859602", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAERGQLPPYAKRLCCRPGYGSGCRLGQQAGDTGPGSGTFCAGPSSAAAAAAAAAAATAASLVLLPLGKTQSPESLLDIAARKVAEKWPFQRVEEQFERIPEPVQRRIVYWSFPRSEREICMYSSFDTGAEGFTAPGSAAGNTASGGAVDAVADENRLPFRRGMALLDGGCVDNVLQVGFHLSGTVTEPAMQSEPETVFNVAISFDRCKITSVTCSCGNKDIFYCAHVVALSLYRIRKPDQVKLHLPISETLFQMNRDQLQKFVQYLITVHHTEVLPTAQKLADEILSQNSEISQVHGAPDPTAGASIDDENCWHLDEEQVQEQVKLFLSQGGYHGSGKQLNLLFAKVREMLKMRDSNGARMLTLITDQFMADPRLLLWRQQGTAMTDKYRQLWDELGALWMCIVLNPHCKLEQKTSWLKQLKKWNCVDVCPWEDGNHGNELPNLTNALPQGANANQDSSNRPHRTVFTRAIEACDLHWQDSHLLHIISSDLYTNYCYHDDTESSLFDSHGWPLWHEHVPTACARVDALRSHGYSREALRLAIAIVNTLRRQQQKQLEMFQARKKELLYRGITSITNLEGWVGHPLDPIGTLFSSLMEACRVDDDNFHGFSDFMENTSQHKSLEYQHLPAHKFLEEGESYLMLAVEVALIGLGQQRIMPDGLYAQEKVCRNEEQLISKLQEIELDDTLVKIFRKQAVFLLEAGPYSGLGEVIHRESVPMHTFAKYLFTSLLPHDAELAYKITLRAMRLLVLESTAPSGDMSHPHHIASIVPNRYPRWFNLSHIESQQCELASTMLSAAKGDVQRLETVLQSIQKNIHSSSHIFKLAQDAFKIATLTDSLPDITLLKVSLELGLQVMRMTLSTLNWRRREMVRWLVTCATELGVHALDSIMQNWFTLFTPTEATSIVATTVMSNSTIVRLHLDCLQQEKLAGSARTLALQCAMKDPQNCALSALTLCEKDHIAFETAYQIVLDAATTGMSYSQLFTIARYMEHRGYPMRAYKLATLAMTHLNLSYNQDTHPAINDVLWACALSHSLGKNELAAIIPLVVKSVKCATVLSDILRRCTLTTPGMVGLQGRRNSVKLMSLDKAPLRQLLDATIGAYINTTHSRLTHISPRHYGEFIEFLSKARETFLMSHDGQIQFTQFINNLKQIYKGKKKLMMLVRERFG", "length": 1168 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0Z0M2-1", "protein_name": "Tumor necrosis factor ligand superfamily member 10", "gene_name": "TNFSF10", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MLPAGGPSPAHTCGAVLVAAVLLQSVCVAVTYIYFTNELKQFANADLVHSCERGHPLSPPPPPDVPQTAVTRPTKAEGGAAPVGASCSIGQSRRAQSDLRQRAANAASPQHGPPCAARSRARCSCPRCTAGPRVCRRTQQKLWDTYSRSGTACLTGEELGDLIQNLDVVESKDRVADPCWQVKWHLGKLIKKMMSRILQENMSAINGDRTQALPRRDEPPQGPTLRIAAHLTGSSKRSSASPHIDYLSYRGIGHKIHSWESSRRGHSFLYNVELWNGELVVPQTGFYYIYSQTYFRFRENEDEDSGLLERIKNPKQLVQYIYKLTNYPDPILLMKSARTSCWSKKAEYGLYSIYQGGVFQLKREDRIFVSVSNSDIVDMDKEASFFGAFMIS", "length": 392 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0ZCD9-1", "protein_name": "Mab-21-like HhH/H2TH-like domain-containing protein", "gene_name": "LOC124418390", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MALVLVLALLVRALIVSGSDHAVMLERVQQHEKEQRNGEQSWVDMSALLFTLLHYWKIWFCTGLFVFLFWNMWRSLKRKQHEEGGQQEQQEREEQVEEVEREEQQEQVEEEEQLERVEELEQEDQVEHVEQEEQEEREDQGEQVQQEEQVEEVEQEDEEEEYFHHSALTRYIARRAWEKMQGKATKCVLVEELMSDLLQTYTFVCSNSFYPVLQPAIGVGSAFEGWSPCEEDIVYRLLVPIKAPHGHVFHPELGEEGEVLARNSRIRVELVCMCTREQQLGDVLCFLHHSEEELSQNQQPSLLQTLCTGSYLDVQKTAAWFNKQVPRTWRLTHRAHRYGLKVLPSSRSCKLQVTDTSSGEKVHVELLFGVQQGNLDIFLSSQNAEAVFTPSTTWPQSCAVAERKYFEYVARTAGPNSCHLVCLRLFAHILVGMGFSTYAIKTLLLHLLAIIPLEDWRRRHFLSRLENLLQYLQYCLNDKVLNHFLLGNATMPDEVVLPQAFQTASPLNLFQHLEQDPDAHSRVLRDFKELKDRLFRLLLFGR", "length": 542 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0ZD85-1", "protein_name": "Mab-21-like HhH/H2TH-like domain-containing protein", "gene_name": "LOC124418382", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MALVLVLALLVRALIVSGSDHAVMLERVQQHEKEQRNGEQSWVDMPALLFTLLHYWKIWLCTGLFVFLFWNMWRSLKRKQHEEGGQQEQQEREEQVEEVEPEEQQEQVEQEEQLERVEELERVDQVEHVEQEEREDQGEQVQQEEQVEEVEREDEEDEYFYHSALTRYIARRAWEKMQGRATKCVLVEELMRDLLQTFTFVCPNSFYPVLQPAIGVGSAFEGWSPCEEDIVYHLLVPIKAPHGHVFHPELGEEGDMLARNSRIRVELVCMCTREQQLGDVLCFLHHSQEELSQNQQPSLLQTLCTGSYLDVQKTAAWFNKQVPRIWRLTHRAHRYGLKVLPSSRSCKLQVTDTSSGEKVHVELLFGVQQGNLDIFLSSQNAEAIFTPSTTWPQSCAVAERKYFEYVARTAGPNSCHLVCLRLFAHILVGMGFSTYAIKTLLLHLLAIIPLEDWRRRHFLSRLENLLQYLQYCLNDKLLNHFLLGNATMPDEVVLPQAFQTASPLNLFQHLEQDPDAHSRALRDFKELKDRLFRLLLFGR", "length": 539 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0ZE07-1", "protein_name": "LIM domain only 1", "gene_name": "LIMO1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MVLDKEDGVPMLSVQPKGKQKGCAGCNRKIKDRYLLKALDKYWHEDCLKCACCDCRLGEVGSTLYTKANLILCRRDYLRLFGTTGNCAACSKLIPAFEMVMRARDNVYHLDCFACQLCNQRDSNPMGWYGSHPVTAAWEAEARTTSLGQPGVRAAELP", "length": 158 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0ZGC1-1", "protein_name": "Ig-like domain-containing protein", "gene_name": "LOC124416945", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MVAGSPALLLLLSLGLCFTGAQGQGNTMAVSFLNRSMKHPKEGQRLGLECHTYKTSWGVSWIRLDKDGNLHFIVYISKFSSTTFPGNKGASSQFEVSKQGSSYRLTVKNFRAQDQGIYFCIANINQVLHFSSGQRAFFPVTTTTAAPTTLRAVTLTATTQSSQVTMKDISQHSPDPGRSKENMPNFCCKLVMWVNLACACLLLLTAITITTTHCQRPSSP", "length": 220 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0ZPB4-1", "protein_name": "trypsin", "gene_name": "LOC107049069", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MKFLVLVAFVGVAVAFPIRDEDDDKIVGGYSCARSAAPYQVSLNSGCHFCGGSLISSQWVLSAAHCYKSSIQVKLGEYNLAAQDGSEQTISSSKVIRHSGYNANTLNNDTMLIKLSKAATLNSYVNTVPLPTSCVTAGTTCLISGWGNTLSSGSLYPDVLQCLNAPVLSSSQCSSAYPGRITSNMICIGYLNGGKDSCQGDSGGPVVCNGQLQGIVSWGFGCAQKGYPGVYTKVCNYVSWIKTTMSSN", "length": 248 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V1A1Z3-1", "protein_name": "Bridging integrator 2", "gene_name": "BIN2", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MPSLYHPNAIPVPFPSHPCTTLMSSLTHHIIPVPSSCLPNVIPIPYHPHVISTLSLLHPHFIPMAFLNLPHAIPVPPLIHSCAVPMSYHPFPISFSFPSPSHPSIAPMQSPSYPYPTPVPPPFHLLPIPIPTPVPPPCHSCSIPIQPRCRLHAILVPFPPHCHPHPVPAPSPPHPSAIPMPSHFHPHPIPVPPHTISIPSPPQCHLHAIPVPSPTHPHPIPSHPRFPHPLWAQGHPHPRGSNLSPPIPPPPPNTFALQNEGNKLYKDLKAFVGAVKVMHESSRKVAETLQEIYSTEWDGHVELKAIADSNDLLWDDYEAKLGDQALRLMENYLAQFGDIKERIAKRGRKLVDYDSARHHLEALQNAKKKDEAKIAKAEEEFNRAQAVFEELNRELREELPVLYGSRIACYVTIFQNISNLRDIFYKEMSKLNRDLYEVMGKLDKQHSSKVFIIKGVPSKRRSLLISAPVSPPAAYPCPGKAPNWDPSSGAEQTPTSPRVGSDATEDVPNGLAAPGPAEPGAPMPGPPPASPTSVRSASESESECSEESREIDLSPKEMEVSVGSGCPEYPKTEGAAKGEVEGIAASMASMIVSEAIAAATGAAPGDSDGVGGGDSTDSEISPAEGAWGGPSPGGSEERVEGTDVSPEVGSDAGPCEHGTPEPPQQDVSCDPPQDPSESLTPL", "length": 682 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V1A7J1-1", "protein_name": "Mitochondrial transcription termination factor 4", "gene_name": "MTERF4", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAGRLLGLLRARAPRAVLPAPGPASRHRCGTAGPEEGEAAELLAMGFSQAQARRLRLLRPGLEPQRRAEAAAQLLLLGLSAEAALGLLERSPGLLRMETARLKERAEYLRRLGLEGERGGPLPRGVHAAPAEDGGGGAAAAGAVSVHGRAADRAAAELPRGAAGGAGPRAAPLPGAGRRAGRSGGVAGAARPALSSARLHAQYAYFRMGVRQKEMVKARLFRTPFAELRNRHVFLERRGLYRTPHKGQSQSGNPALRDVLRPTEGDFVAGVARASPDEYEVFKRLLAREEEEMEEEEEEDEEEEEEEEGSAALHAEGGDRDWHSSEPSPIAPCPPAPQ", "length": 338 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V1AKD9-1", "protein_name": "Borealin", "gene_name": "LOC121107214", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAPARRKAAAGARGRKLSAFLKDFDREVRSRVEQLRTNGERLVKEMENLYDVELLRLPAALREMNWLEFFAKGGSQKVVEEAVTADLGITEINKLTAELIQTPLKIVTKEKSKQGIEATEEAAEVPLLPPAKKAKHDSQLLLEQAAASTNPRNGKVRTSTKKAPVSRSRRAPSARVKRVSKRSSKSSFITPATGRNLDLCARGGASIVTPRFDSRVFKTPGLRTPAVNERVYTISANGSPLADGNDVFITVPVGGGESIRLTASDLTKKNLLHLNPEARGIMKKLSVRLAQACSSAKTHR", "length": 300 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V1AMC7-1", "protein_name": "ODF3A protein", "gene_name": "LOC121107218", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MPASMDGAWVGTWRPHRPRGLISAQFPSPGPQYSIPGTTGYVGHSPTKARAPAYTFRGTKPPAAGSCGPGPCYFVEPAITRNGKYVAPGAQLRGRPVTKTTVTPGPSDYRTEAANRHVFKCPPVQSMAFRREPLRTDHPPGPGTYTLPRLMGPNTVYTSASPCYSVRGRSQRGRFDEDLAKTPGPAALPKVPVDAYKTRAPAYTMAARPKAGEGKAAKPGPADYSVGRVTLIKPQAPASTFGIRHSLYTTPLIVE", "length": 255 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8W4F7J1-1", "protein_name": "40S ribosomal protein S26", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MQPIHCTNCARCMPKDKAIEKFIIRNIVEAAAVGVISEVSVFAAYVLPKLYAKRHYCESCAIHSKVIRNRSREAQKVRTPPPRFRPTGAALRPPPKCM", "length": 98 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4F8K9-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258234", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRNHTVTTFILLGLTDEPQLKTLVFIFLFLTYMLSVTGNIISLTSTDSHLKTAMYFFLQNFSFLEIAFTSACIPKYLYNIATGDKTITYNSCATQLFFTDLFAVTEFFLLATMSYDRYVAICKPLHYVTIVNHTVCRRLIFGSWLAGLLIIIPPLSLGLKLEFCDSNVIDHFVCDAAPLLKISCSETWLIEQMVIVCAVLTFIMTLMCVVLSYVHILKTILQFPSAQQRKKAFSTCSSHMIMVSISYGSCIFIYVKPSPKDSLAVNKGVTILTTSIAPMLNPFIYTLRNKQVKQAFNDAIKRIALFSKN", "length": 309 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4F9E2-1", "protein_name": "UPAR/Ly6 domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "RLEFSSLSPAEVPLVAAAGGRGAFDMRCHECDTKNTFACDHIVTCPRGIRRCLTLSIRLSSREIYVYKGCTRNCTFIYADEQPPPGERKPPRSNSLYFVQCCNAITCNRGGPINLEKDITPPLILEEELGGTVRLGEATLFLSVASVLVSHALT", "length": 154 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FBC5-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MLTHSFSFFSSSSSSSTYSSSYPLLPLLLQPQNQFRIWALKDYGQRNSTSLHDFILLGVVATFYLITLVGNTAIILASLLDSHLHTPMYFFLRNLSFLDLCFTTSIVPQMLLYVYMWLGSIECLLLAVMSYDRFTAICKPLHYLVIMNPHLCLKMIIMVWSISLANSVVLCTLTLNLPRCGNNLLDHFLCELPAMLKIACIDTTAVELSVFALGIAIVLTPLILILISYGYIAKAVLRMKSTAGQRKAINTCGSHLTVVSIFYGAIIYLYLQPGNSASKDQGKFLTLFYTIITPSLNPLIYTLRNKDMKEALKKLMRVDHKSTKSKRTWKS", "length": 331 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FBS2-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258626", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRNHTAITTFILLGLTEDPQLQLLLFLFLFLTYILSVAGNLTIITLTLLDPHLKTPMYFFLQNFSLLEISFTTACIPRFLYSISTGDRTITYNTCFTQLFLTDLFVITEFFLLATMAYDRYVAICKPLHYMTIMSNKLCKTMVVCCWLAALLIILPPFSLCFHLEFCDSNLIDHFACDASPLLKISCSDTWLIEQMVIACAVLTFIITLVGVVLSYIYIIRTILKFPSAQQRKKAFSTCSSHMIVVSITYGSCIFIYINPSAKEEVNLNKSVSLLISPISPVLNPFIYTLRNKQVKQALHDSLKKTAFLLRK", "length": 312 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FCJ2-1", "protein_name": "Histone H2A", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSRKRNLPQCNPPKKQALSRSSRAELQFPVSRVDRYLREGRYAQRLSSHTPVFLAGVLEYLTANILELAAGEAHSSRKMRIAPEHVQRARSHNETLSSLFQASSVSRGAEEEAEEPLPEAGR", "length": 122 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FD42-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTALNHTGVSHTVFYLLGIPGLEDQHLWISIPFFISYVTALLGNSLLIFIILTRRSLHEPMFLFLCMLAGADLVLSTCTVPQALAIFWFRAGEISLNCCITQLFFIHSIFVFESGLLLVMAFDRYVAICYPLRYTTILTHPLIGKIGVTIVLRSYCAIFPIIFLLKRLTFCRSNVLPHTGCEHIGLAKYACNDIRVNIWYGLFVIVSTLLLDILLIFVSYMLILHAVFHMPSQDARHKALNTCGSHVCIIILFYGPGIFTALTQRFGRHIPAHIHILLANVCILVPPMLNPIIYGIKTKAIQEQVALILFPKYR", "length": 314 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FH98-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "VCHYGNYYSGLSCSCGYGCGYSRCGCNCDYDKCGYRCGYGGYVYGCCHLSCCGRYRPYGFY", "length": 61 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FHY5-1", "protein_name": "Ig-like domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "DTGSCGAIVLTQTPLSLSVSPGEPASISCRSSQSLEEYGKNWLSWYQQKPGQSPRLLIYQATNRASWVPERFSGSGSGTDFTLKISRVEAEDAGVYYCQQYKEFPPTVIQPLTQTPLLGAQLHTWLCVVWGAEGQKL", "length": 137 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FIZ4-1", "protein_name": "Envelope glycoprotein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRPTLSRRHLPTRGGEPKRLRIPLSFASITWFLTLTITPQASSKRLVDSLTSPKPLSLTWLLTDSSTGITINSTQREAPLGTWWPELHVCLRLVIPGLNTMSTPPDILRAYGFYVCPGPPNNEEYCGNPRDFFCKKWSCVTSNDGYWKWPTSRQDRVTFSFVNSYTSYNQFNYGHGRWKDWQRQTQNRQISCSPSDLDYLKISFTEKGKRENIQKWINGMSWGVVYYRGSWGGEGSILTIRLRIETQMEPPVAVGPNKVLTEQGPPIQGQRPSPNPSDFNTTSG", "length": 284 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FJ61-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSSTKNKHLMKGSKKGPKKKVADPFSKKDWYDGKAPAMLTKKRNIRKTLVTGTQRTKITSDGLKGHVFSSEPCQSAE", "length": 77 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FJT7-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MKNPEVRKIHSAVFLITYLSTILGNLLIVVTMVTSQSLRSPMYFFLTSLSLMYVTYSSVIAPKMIVDSFSETTAISLEGCMAQLFAEHFFGGVGIILIIVMAYDHYVVCCLLLGGAWVGGSIHATIQLLFICQTPFCGPNVIDCFMCDLFTLLKLACMDTHLLGILVILNSGVMCMAIILILITSYVVILCSLKSYSFEGQHKALSTCGSHLIVVVLFFVPCIFLYVMPVATYPIDKAMAVSFTIVAPMLNPLTCTLRNAEVNNAMRKLWMKQNTLCYH", "length": 279 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FKQ6-1", "protein_name": "Large ribosomal subunit protein uL5", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MVQDQDEKKNPMWELGIHKLCLNICEGESGNRLTRAAEVLKQLTGQSPVFSKARYTVRSFGIRRNEKIAVHCTVRGAKAEEIFERHLRVREYKVQEHISLGTKYDPSIGIYSLDFYVVLGRPGFSFADKKHRTGCIGAKHGISKEDAMSWFQQKYDEIILPGK", "length": 163 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FKY3-1", "protein_name": "Large ribosomal subunit protein eL27", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGKFVKPGKVVLVLAGRYSGRKAVIVKNTDDGTSDQPYSHALVAGIDRYPRKVTAAMGKKKIAKSSKIQSFVKYSVDIPLHKTVVNKDVFRDPALKRKARREAKVKFEERYKTGKNKCFFQKLRF", "length": 125 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FLM5-1", "protein_name": "Small ribosomal subunit protein uS14", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGHQQLYWSHLRKFGQGSRSCCVCSNWHGLIRKYSLDMCHQRFCQHMKDPGFIRLD", "length": 56 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FNC8-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGQRNQTSSLADFILEGLFDDSPAHAFLFSLTMVVFLIAVSGNTLTILLICADPRLHTPMYVLLTNYLSGTKSISFVGCATQYFLFLSLGCAECILLTFMSYDRYVAICHPLRYAVLMNRKVGQMMAVMSWLGASVNSLIHTVILMHFPFCGHRNIHHFYCEFPAVVQLVCGDITVYEIAVYIGDIVLLLLPIALISASYVFILHSVIRMHSAGGKRNAFATCSSHLTVVSLWFGACIFSYMRPRSQRTPLQDKVGSVFYTIITPTLNPLIYTLRNKDIAKALKRVLGREMITQNPKVRLP", "length": 301 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FP10-1", "protein_name": "Ribosomal protein L19", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSVLRLQKRLASSVLRCGKKKVWLDPDETREIANAKSRQQIWKLIKDGLSIQKPGTVHSRARCQKNTLRKGTASAGMPKKSVPERDGNVFKNKRILMEHTHQLKADKARKKLLADQPEARRSKTKEARKRRQERLQAKKEERNRTEVETKFCRLI", "length": 155 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FP36-1", "protein_name": "Small ribosomal subunit protein eS24", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MQDTASIRTRKFRTNQLLPGKQRVIRVLHPGKATVPKTEIWGKLAKMNKRTPDVIFVFGFRTHFGGGKTTGFGMSHDSLDDYTKTNEPKHKRARHGLYEKSKTSRKQRKERKNRMKKVGGTAKANAGAGQKGGV", "length": 134 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FQE1-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTALNHTGVSHTVFYLLGIPGLEDQHLWISIPFFISYVTALLGNSLLIFLILTRRSLHEPMFLFLCMLAGADLVLSTCTVPQALAIFWFRAGEISLDRCITQLFFIHSIFIFESGLLLVMAFDRYVAICYPLRYTTILTHTLIGKIGVTIVLRSYCAIFPIIFLLKRLTFCRSNVLPHTGCEHIGLAKYACNDIRVNIWYGLFVIVSTLFLDVLLIFVSYMLILHAVFHMPSQDARHKALNTCGSHVSVIILFYGPGFFTTLTQRFGRHIPAHIHILLANVCVLVPPMLNPIIYGIKTKAIREQVAHLLFPKQK", "length": 314 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A9J7F7T0-1", "protein_name": "Protein transport protein Sec61 subunit gamma", "gene_name": "LOC100757015", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MDYVMQFVEPSGQFVKDSIWLVKRCTKLDRKEFQKVAMSTAMVFAIMGFTGFVKLIHIPVNNIIVGG", "length": 67 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A9J7GY23-1", "protein_name": "Tetratricopeptide repeat protein 16 isoform X2", "gene_name": "Ttc16", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MTDSSTEESVNVQTQKIPKLQVPETRETTLQRIFGTSQVFYSVSGVVKPRLTESTVPFRVREYYHQGHHCLEQEDWEMAVLYFSRALHLNPDQVEFYIFRAEAFIQLCDFSSALQNLRRAYSYEPENSKYLERLAFVLYLQGQCLYELCDFQEALYVFLQASDLQPQNPSFSYRCMACLLALNRHQDCLSLVTREVKQGRATADVYILRARIYNFFQKPKLCYQDLRSALLFNPKHPQAKGLLQVMVDQAKKSLQDASILAVQGKLHRALKRISCAIENNPLDPNLFLFRGTLHRRLQQFDPAVEDFLKAMDMVTDSQDNLVQKTQRQLLLTYNDFAVHCYTQGAYQEGVLLLNKAIRDEQNEKGLYINRGDCFFQLGNLAFAEADYKQALELCPKDEGANLRMGVLQEKMGLCEQTRRQFQKAEDHFSAAIKYNPVNAQYYLHRAKNRQLLQNIVGACQDIATVLLLNPKYPKMAPLMAKLFPGMSVEEVLNSHVAQLAKLQLRRMIESGPKASHPQSIVAKRLIERQKAQALMESWNWEQLFTRNPEEEVAPSESLQGKTLREKIEFKREVVEEKKVKILRKVTSLSDSYVDQTSSGSEFSILSPSTLETEVSTMEYKSTSNTAASSAERLLPQYLVTTKYKESLGLSMAPNVTQVSEDLHKSLTENIPDDGPRHHSSKAEATQRPKPRKTEPSQSLGKQRPSQRPSITEATKGPKPRKNRPALSPRQRLRRAKAVQAQNWKPRTNSNSQKTSSLLSNIAVIISSSNEAQDQSPVPSKADDISSYNDSTATSSTNTDSLRLSIHLSKPKYSKDQSPSHNKEEVSPTSNNYAAP", "length": 835 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A9J7GZF8-1", "protein_name": "Protein EURL homolog isoform X2", "gene_name": "C4H21orf91", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MIIKRKATVIHHKGTMNEEEQFVNIDLNDDNICSVCKLGTDKETLSFCHICFELNLEGVPKSNLLHTRSLRGHKDCFEKYHLIANQDCSRSKLSKSTYEGVKTLLTKKINWIVQYAQNKDMDLDSECSKNTRHHLFNFRHKPDKKLLPQFDSQVPKYSVKGIAGSTGGLSSYTQRILEQRENTDFGLAILQDSDALWPHKHNQAQKKEETSSGPENVQTQNPRYSREELNSMTLDEVEQLNTKLQQQIQEVFEELTHQVQEKDSLASELHVRHVAIEQLLKNYSKLPCLQVGRAGPRSHLPINN", "length": 304 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A9J7JMJ4-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100771730", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MDFVNISLVTEFFLVGLTDQPELQMPLFFLFLAVYLITALGNLCLIILTVLNSNLHTPMYFFLFNLSFIDICYCSVFTPQMLMNFILRENIISYMECMAQVFFFCFFVVSECYVLTSMAYDRYMAIYNPLLYNVVMSPNLCLNLMFGSYFIGFSNAVAHTVCMLRLTFCDTNIINHYFCDIPPLLQLSCTSTYVNKLVIFVFASINIIVPTSTILVSYGFILSSIFHISSSEGRSKAFSTCSSHIIAVSLFFGSGALVYFKPSSAVYMNEGKISSVFYTNVVPMLNPLIYSLRNKDIKVALMKSLNSRNL", "length": 310 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0AA74KSW7-1", "protein_name": "Predicted gene 3002", "gene_name": "Gm3002", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLNSSKLGVWAAGVPPSSPTLLFRRWVMKVESLISQPMTSGKNELQDHLIFISEKALHKRLFQKENGDEGVTRPTEKEEGILSHEKGRRKWLWRRHRSARNTSTQNSKMTKKRSKINELEELKLDMRKISNDMEEMCGILNLYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLHENVRILLNENRRLLVEQAGHKCPVGKKRGSLRRPARTSVSQVPRNTSPAESRTWHRPGHDLPQREVLEEEH", "length": 280 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0AAA9RU54-1", "protein_name": "Small integral membrane protein 17", "gene_name": "SMIM17", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MQSLRPEQVRGLLEPERAKTLLPRENKAWEKRAAFAKDWVAVEVGASGCGSDEKDLPSPKTLVPQEWSSVEEDDESEDSQPHWAAALPTSPSCPSQDTGTGSGADLCLQCSSPRTPPWLPWAFSHTIESALPTPPRAWLWSLL", "length": 143 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0AAA9RY85-1", "protein_name": "Core Histone H2A/H2B/H3 domain-containing protein", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MNMPEPAKSAPAPKKGSKKAVTKAQKKDSKKRKRSRKESYSVYVYKVLKQVHPDTGISSKALGIMNSFLNDIFERITGKTSRLVHYNKRSTITSREIQTTVRLLLPGELAKHAESEGTKAVTSIPALSKYNMPSRC", "length": 136 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0ABK0KVZ2-1", "protein_name": "Eukaryotic translation initiation factor 1", "gene_name": "Eif1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "EFGFRSVASAGWGAACPLGLRHVISCGGRAGLEQKARALSSSSTGLFPEGQQRAPPDFSDDICTDKKKNQERGINKWPTTTRNKNYFFVDPFADASKGDDLLPAGTEDYIHIRIQQRNGRKTLTTVQGIADDYDKKKLVKAFKKKFACNGTVIEHPEYGEVIQLQGDQRKNICQFLIEIGLAKDDQLKVHGF", "length": 192 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0ABK0L002-1", "protein_name": "Oocyte specific homeobox 2 like 1", "gene_name": "Obox2l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "ILQSVQNTDMIEGPSFLPKFQMSSYTPMDTSSQLPQEPSWNLAFQMGQSPLVTSRTPMQSSPSVPEQNLNWQESQGSSRESSIQMQPGPVMDPGFPTLRSPSGHPSHQRPSRPSSRSGFHVPIEPMALSDKHGGKQTGPVAPRKCRKERTQYSAKQKSVLQEHFAECQYPDKKLCLELATLFGVTENEIKVWFKNNRAKCKQKNVPEALPETNGGPEAVSWSTDFPGSIAVVGCDQGEPMATAILDVDSTPKLNCSQESSLDGNWTYDGAMCCLPEDVLDGNDPVTAGDSGESAPVEAQSDLAAAGAPVAMAVDTQNPEECEDLPLLDEGVWQWMLEDFHQLEDWFTKNYIESPSSASHPLD", "length": 362 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0ABK0LHI6-1", "protein_name": "CD27 antigen", "gene_name": "Cd27", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAWPPLYWLCMLGTLVGLLATPAPNNCPDRHYWIGAGLCCQMCGPGTFLVKHCDQDRAAAQCDPCIPGTSFSPDYHTRPHCESCRHCNSGFLIRNCTVTANAECTCSKGWQCRDQECTECDPPLNPALTSQPSEAPSPQLPPPTHLPYATEKPSWPPQRQLPDSTVYSRLPSQRPLCSSDCIRIFVTFSSMLLVFVLGGILFFHQRRNHGPNEDSQAVPEELCPYSCPREEEGSVIPIQEDYRKPEPASYP", "length": 251 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0ABK0LYA6-1", "protein_name": "Prostate and testis expressed 2", "gene_name": "Pate2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLSCLTSELQGSACLCLPSTGSYKHILQHLDLGTMCYKCKKYHLGLCYGLMRSCTLKHRQSCAAENFYILTNRGQSMYHYSRLSCMTNCEDINFLSFERRTELICCKHSSYCNLPMGL", "length": 118 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0ABK0M6C3-1", "protein_name": "Prohibitin", "gene_name": "AABR07037878.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MYNKNIKNSISISVCVGGVGGVRARAHAHAHTSPHACTRVIHAFVMLEVGPRDFVHIKKAFRGIDVKKPVIFDCRSQPRNVPVVTGSKDLQNVNITLRILFRPVTSQLPRIYTSIGLDYAERVLPSITSEILKSVVARFNAEELITQRELVSKQVSDDLTERAATFGLILDDVSLTHLTFGKEFTEAVEAKQVAQQEAETARFVVEKAEHQKAAAIISAEGDAKAAELIANSLATAGDGLIELRKLEAAEDIAYQLSSSQNITYLPVGPSSVGPSVRQSMFLRLPQ", "length": 286 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0AC58FXL6-1", "protein_name": "Cytochrome P450 2X10.2 isoform X2", "gene_name": "cyp2x10.2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSDLRGIYSYMLSTVNSLVRDSSLTNFKKEFCVHAYLLSVCIQYQSSVWSSSRSVTMLTALVLLCLGAFLLYLQLRIRRPKNFPPGPAPVPIFGNLLQLNRISPLKDFDKFAQHYGSIYGIYIGSQPAVVLTGQKMIKEALITQAAEFSGRSNNMMFSHVTGGKGVIMADYGESWREHRRFALTTLRNFGLGKKSMEQRILEEVKHICLLLEESAGKSIDPQHLYHQAASNIIASVIFGSRFNYKDAYFQTLITSVEDLTKITIGPWAMLYEIAPVLRIFPLPFQKAFQYFEQITKHVLKVVEEHKTSRVAGEPRDLIDCYLEEMENKSDHRTSFDESQMVTLLFDLFIAGTETTSNTLRTLTLYLMTYTHIQEQCQREIDEVLGARDHVTYEDRNAMHFVQAVIHEGQRVADIAPLSMFHSAKTDTQLRGYSIPKGTIIIPYLSSSLREEGQWKFPHEFNPQNFLNEKGEFVKNDAFMPFSAGPRVCLGENLARMELFLILVTVLRRFRLVWPKDAGEPDFTYIYGGTQSVKPYRVIVEPRMHGEACKFVD", "length": 552 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AC58J797-1", "protein_name": "Uncharacterized protein isoform X1", "gene_name": "si:dkey-233e3.2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MANAKQLLKNSLDELVEAELKEFQWYLINDHRDISKAEMEKADRLKTVDKMVSCFGPKGAVKTTVDILRKINQNELAEELENKHKQGNCMSARAEGAVLETCKSPPFDYTNTSRELKKKLKEDYEKILVGNSQTGHKKYLEDIYTDLYVVENETGGRERQHEVIQMESKHNQQDRPLKCNDMFKVQPDTGRKHRRILTLGIAGVGKTVSVNKFILDWAEGKDNQEIVFIFPLPFRRLNLIKEEKYSLIGLLNKYFFSISGGLSSLPEKQGKVMFIFDGLDEYRFKLNFKKDDGFTDVNKEMTVSEIITNLLKRHLVPSSLMWITSRPAASSLIPRDLIDQVTEVRGFIDEQKEHYFIKNSSPEVARNIIGHIKKSRSLYIMCHIPVFCLISLTVLQPLLGQESNEKTPTTLTGMYINFLLSQKQQMKEKYRNDTESEANACSFDEIVLKLGKLAFKQLQKGQLIFYKTDLEKCGLDVRQGSVFSGLCTRMFQEENHYSGEQVYSFVHLSVQEFIAALYVFFTYKNKKANLFLDSWKKELKWKLSEKPLFKLHTAAVKKTLQSKNGHLDLFLRFLMGLSLESNQSDMKELLPWLKLKTGMIKDTTDYIKKKIEEENSAERTINLFHCLNELNDDFVEELQKSLCSGNLTAQDLSSAQWSGLVFVLLMSEETQEKFELQKYRRSDEALMRLIPVVKNTTRALLQCCNLTAQSCESLSSALQSSNCVLRELDLSNNDLQDSGVNLLSNGLKSPKCKLEILRLSGCMVTEEGCGFLSSALTSNPSHLRELDLSYNHPGDSGLKLLSQKLEDPNYTLNKLNLDHGGEKWFTAGLHKYACFLTLAPNTAHIELRLSEENRRVTRVGERQQYPDHPDRFDHHAHVLCRESVCGRCYWEIEMNAGDRVDIAVSYKSIKRKGRGYECVLGQNAQSWALICYVNRVAFRHNMIETRLPVKLMSRRIGVFVDHSAGTLIFHNIYRDSMSLIHSVQTTFTEPLYPGFWVEYGSSVKLC", "length": 1006 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AC58JHM1-1", "protein_name": "Phoenix isoform X1", "gene_name": "pho", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDLRSKGDTSVGEVMEADPRAELIFETPPPDVVSSINACFEEIDSALKIRRDPSVHSPPSDSDSESLFITQSVTKVVHTKRRLRSSKKPDSISDDSGYVRERRLSENQQTECEEESRSLRSSRRKRSKWEMYASARKATFPFLMKSLKTQHLPIRKHQILENSEVGGFFKCIKKIKTGSVKMGKVISSHLFQSPISDSSEEEDQNSEHDVISVDKALFVPGYKRGINFKWLPDFIRERRTLENYLSNGVDKEKKTEQIIEYRQRNQHPQRTSAKALSKSSQVSKKPKKQDTHEVLASCSDHEDLEIAECAENSHEGHKVVIEETQRQTVEEASAHLEHEDDLNCKVVEYRKRKRHPKRTSAKALSKSSQVSKKPKKQDTHEVLASCSDHEDIESVECAENSHEDHNVVIEETQRQTVEEASAHLEHEDDLNCKNQPDVDQPNESNFIGPPQEGDISTQSDTQQTDSDIGSVDLFSPLNSPKRDDQIPNTTSITANVEENDQDSDVTQIESEGQHVSTFTQETQKCFANEEYDSDETHIDTESLSRFKPRTPNKQFTSTKHPEIPQFRVQSPKPPSRQAETVNVQLSPKHLPLSNVPLSEVPISPCESAIVGRQKTMVETETDSPMFKITGPSFLKRKRKRTKDKNAAADFKQHDTNGDVGQMVSCPGDDITGLKAVPIENIEACGVEHEMAIGEQTEELGLKSKELLEESVLSTVNSVSTKSKREKMKKYKVKECEAVENQLVETSKKAKKKKKDKERIATSYPEENNLTNIQSNEGFDSAELRVKEVNQSSQSLNTDQPTCVQTSEEITGETELKKKTTRHETDDPLYESVGLDVTLASQFDVGLRIDEQQEGLVTEEAERDERLQGKAMKVAKGKKKIQDTSFQVDHDIGLDKQRSDSGAKPANLDLDGLESLTIKKKKKKKKKHKLKEKTDPKLDFDFDHNVQFFQTDRLQTTDSVLLDSTHTNKQKKKKLKCQNDTDQSSDLKQLHVVGSKLQTIDLPKTDKHMERTGVSSSDALLEHMDDRTLGMRENNTIQTDQIEHLQTSEEVTRCSSPRLSSDKKREKTSVHPNLDASSVFQFDGFKANEDQAITQNTTKEKQISSEQLENNLVGPPSQVENIANVNSSVLLDHTHMNTLREGQLKEQTYKELALAFGLKQLCIVVNKLKTTDLPKTNKNMEGTGVGSSDELLKHTDDRTLETRENNTIQTNQIEHLQTSEKVERHSSPRVTRLSFAKKWMKTSVDSNLDASSGSQFDGLNSMAKEDWTFSQNMDLPLKRTKNKQKDKERTGVSSDALLKRMDDRPPEMRKKNTIQTNQIEYLQTSEKVTRRSSPRLTRLSLAKKMEKTSVDPNLDASSGSQFDGLKEASKEDRTAPRNSIEEKQSDAISSEGLENNPAHLVSTNKSDNTSPSSQVDNIVGLQSDANSVLLDHTHTDKQKKKKIKHKLIEQTEKELTSEVEDNVQPFQFIELRAMDLPSKRITNKKLKDRKRTGVSSSDAVLKHIDDGPSDMRENNSIQTDKIEHLQTSEEMTRCPSPRLSSDKKRKKKYVDTNLDASSGFQFNWSNGMAKEYSKNSTNISSLDNMHTSKQKKKKKQKLKEQKNVESVGDNVYSLEPDQFSGLQITEIKTKKKDKKRTKQANVEENDLKGILSNKAFKASQTYQLEHIQTSEEIKGRSPNAASKSAKKKKKKKNETKNPQYESVNLDLSLAKEDRTTTQNHTEETQGDGNAVEHLEMNPAGLIKVSKKKKKRENAGIVQLDNIIGLQSGSSTDVKSSVLSDSTDTNKHKKKKRKTLKEQENVEAEGDDVQSVEPDPFSGLQITEMTTKKKRKHKRCEEQRCLRGVSSHEAFKAPPTNLLQHIQTSEEISQCQSPNVAALENGGSPYQLENITEMQPGNSIDINSSEILYSTCTHKQKWKKLKQQENVEADANDVHSAELNLFSELKISEPTTKKKKHKKCVEKCALKDISSNEGIKAPQTSQLEHVQTSKEITQCQSPNAATLKSEKKKKQKRDETEVPQYLDASSVSQFDDVTRLKKQAKVDRTTTQNSSEETQNDDISSKQLEMNPAHLIKVSKRKKKREKAGSPYKVDKIVGLQSGNFTDVNFSQLSDSKRTDKQKKKKKIKLKEQENAEADVDDVHSVELDQFSGLQITKPTTKKKRKHKRCVEESGLRDISSNEAYKAPQTNQLEHIQTSEEITPFQAPNVAALKSAKKKKKKRDKTVEPQCLDASSVSQFDDVKTRAKEDQTLTPNSSKETQGDDSAVECLETNPAGLMKVSKKKKKRENAASPYKVDNIVGLESGNSADVSSSVPSDSTDTNKHKKKKRKKLKKQEIVEADLQTSEEIIQCQSPNVATLKSVKKKKDETKEHQRLDVSSVSQFDDVSRLKKRAKEDRTTIQNSSEETQSADISSEQLEINPAHLIKVSKRKKKRENGRSPSQVGNIVGLQSGNFTDISSSVLSDSTRTDKQKSKQKKKLKEQENVEADANDFHSAEPDQFSGLQITEMTTKKKKKHKRCVEESGLRDISSNYAFKAPQTNQLEHVQTSEEITQCQSPNVAALKSEKKKKNKRDKTDKPQYLDESSVSQFDDVKKRAKADRTTTHNSSEETQKDNISSECLELNPAHLMKISKRKRENKSLGLLSENTADLNSSSLLDGTDTDKHKKKKRKKLEGQENVEADVDDVHSAEPDQFSELQIPEMTTKKKKKHKRCVEESGLKDISSNEALKALQTNQLEHIETSEEMTIKTVKKEKKKRDATEEPHYKSVDLDVSPTESTTEAKLNPTKHKKKRKQSFSGSHDAHEAPERKRKKDRN", "length": 2809 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0MGZ5-1", "protein_name": "Heparan-sulfate 6-O-sulfotransferase 1-B", "gene_name": "hs6st1b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MNDTERNMVERTSKFLLIVVGSVFFMLILYQYVAPGVINFGSPHGYLLGEEDMTIFPTPDPHYVKKYYFPIKDLERKIDFEIKGEDVIVFLHIQKTGGTTFGRHLVQNVRLELPCDCRPGQKKCTCYRPNRKETWLFSRFSTGWSCGLHADWTELTNCVPGVLNKRESKSKKMRKFYYITLLRDPVSRYLSEWRHVQRGATWKTSLHMCDGRTPTPEELPPCYEGTDWSGCTLQQFMDCPYNLANNRQVRMLADLSLVGCYNLSTVPEKRRSQLLLESAKKNLRDMAFYGLTEFQRKTQYLFERTFHLKFIRPFMQYNSTRAAGVDLDNDTIQRIEELNDLDMKLYDYAKDLFQQRYQYKHMLDRREQRLLRGHASFHSPFREDGAGGEGTARLPTEDYMNHIINGW", "length": 407 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A1EC97-1", "protein_name": "Dual specificity phosphatase 14", "gene_name": "Dusp14", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSSRGHSTLPRTLMAPRMISEGDIGGIAQITSSLFLGRASVASNRHLLQARGITCVVNATIEIPNFNWPQFEYVKVPLADIPHAPIRLYFDTVADKIHSVSKKHGATLVHCAAGVSRSATLCIAYLMKFHNLCLLEAYNWVKARRPVIRPNLGFWRQLIDYESQLFGKSSVKMVQTPYGIIPDVYEKESRHLMPYWGI", "length": 198 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A1XQX2-1", "protein_name": "Neurexin-1b", "gene_name": "nrxn1b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MMILHLGAHLLFIGLIVCKANAGSSLRFTGSDEQWVAFPMWNACCESEMSFSVKTTHLNGLLVYFDDEGFCDFLELHVHVGKLRLCFSIFCAESTCVLSDVAINDNRWHSVSIMRNFRNTTLIVDDEVKWEEVKSKRRDMTVFSHLFLGGIPSELRSVSLQLTSKTVKDHTSFTGWIMDVKVNDSEPAIISSAGVHEDLCGSENTCLNGGVCSVVEDKPTCDCSQTGYQGKDCSEGLAHLMMLDRGMEEYVATFRGSEYFCYDLSLNPIQSSSDEITLSFRTLQRNGLMLHTGKIADYVNLALKNGAVSLVINLGSGAFEALVEPVNGKFNDNEWHDVKVLRNLRQHSGVGYAMVTISVDGILTTTGYTQEEYTMLGSDDFLYVGGSPSTADLPGSPVSNNFMGCLREVVYKNNDAELELSRLAYQGDPKLQIHGVVAFKCESVATLDAITFETPESFLTLPKWNAKKSGSISFDFRTTEPNGLLLFSCGRAKQHNKEAKSPVTLKVDFFAIEMLDGLLYLLLDMGSGTTKTLALNKKVNDGEWYHVDFQRDGKSGTISINSVRTPYLCPGDSELLDLDDPLYLGGVPESSSGTVFPTGAWSALLNYGYVGCVRDLFIDGRSVDVRRAAELQRAAGVKPSCGKEPSGKCVSEPCLNRGVCREGWSRYICDCTGTGFLGHSCERDATILSFDGSKFLKVQFSAAMHTEAEDVSLRFRSLRAYGVLMASTSTHTTDTLRLELEAGRVRLTVNLDCNRINCTTSKGPESLFAGQNLNDDEWHTVRVIRRGKSLKLSVDDLPTVDGEIPGDHTQLEFHNIETGIITGKRQLPTMPSNFIGHLQSLMFNGKPYIDLCKNGDIDYCQTNAPIGFKSIIADPVTFKSCSSYVTLPSLQAYYYMYLFFQFKTTSADGLILYNSGDGNDFIAVELVKGYLHYISDLGNGAHLIKGNSIKPLNDNHWHNVMISRDPNNLHTVRIDTKTTSQTTLGAKNLDLKGDLFVGGVPEQMYKDLPKLVHAKEGFQGCLASVDLNGRLPDLMTEALVCIGQIERGCEGPSSSCEEDSCANQGVCLQQWENFTCDCSMTTYAGPLCADPGSTYVFGRQGGVITYSWPPHDRPSTRVDRLALGFITLMEDATLVRVDSSAGLGDYLKLHIVKGNVVAVFNVGTYDINIEENGKLVNDGNYHIVRLTRSGGNATLQVDDLPVIERFPPGHIDSHRLGTGRLPYRRLVEESLPKNGRQLTIFNSQMTIRIGGWQKQQVSGFQGQMSGFYYNGLKVFSMAADGDPNVRMEGSVRLVGELQSSSTPHGGATVYQSSVTEISSTTSNTITITYSTPADEQQTTDELLVASAECPSDDEDIDPCEPSSGTLCCFVPPAGPTGPAISSFPGPAEVFRESNGTTGMVVGIVAGAALCILILLYAMYKYRNRDEGSYHVDESRNYICNSNGAALKEKNTADDDSGSKSKKNKNKEYYV", "length": 1470 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A2A7I1-1", "protein_name": "Zinc finger protein 978", "gene_name": "Zfp978", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFAPHQESGRRTTKRMSASLENTAQCLLTFKDVFLDFSSEEWECLNFAQRTLYMDVMLENYNNLLFVENHCICGNYEKEKVVEQDTQHIFNEHGHIQEKSFKCNESSNIIHESSESTPHKTNHRDATLQSSNLKRHKTGTTKQVCTYKDCVNCLKGSSIISLNQGTHVEKKEHNRNKNLDEVLVSKHKPIVRQNNSEMNTYTCGEFDKCFTQSDNLQSQQRIYPGKKSYKYSESDKCFTQPSHLSIHHTIHSGEKPYKCSECDKCFTDKCTLRKHQRIHTGEKPYKCNECDKCFTDKGSLRVHQRIHTGEKPYKCSECDKCFTQTSHLSIHRRIH", "length": 335 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2A8N2-1", "protein_name": "PRAME like 25", "gene_name": "Pramel25", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVICGHCPDQDESLEEVTEECYSPPTLQNLAIQSLLRDEALAISALTDLPQSLFPVIFEEAFTDGHIGILKAMIPEWPFPYLSLGKQINNCNLETLKAILEGLDILLAQKVQTSRCKLRVINWRDHDLNLWAGSHEGEGLSEFTTEKQPIENSPGCEVKKELKVMTEVLRMKGRLDESTTYLLQWAQQRTDSINLFCRKLVIEGLTKASVIEIFKTVHADCIQELILRRICIEELAFLNPYLKLMKRLFTLTLDHIIGTFSFGDSEKLDEEIIFSLISQLPTLHCLQKLYVNDVPFIKGNLKEYLRCLKKPLETLCISNCDLSQSDLDYLPYCLNICELKHLHLSDICLRDLLLEPLGFLLERVGDTLKILELESCCIVDFQFSALLPALSQCSHLREVTFYDNNFSLPFLKQLLHHTALLSQLISECYPAPLECYDDSGVILTHRLESFCPELLDILKAKRQLQSVSFETTQCSKCGGCYIYDQETQCCHFVELLLA", "length": 498 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2A9Q9-1", "protein_name": "MAGE family member B5B", "gene_name": "Mageb5b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPRGQKNKHHRNRLKNKKHNQEKVHPQKDESQEKGHHKRDDFQDHKEARDNAAVEEKSSCSSPSVPGETLEKPPASKTSSDAGWLSCVSSPATVCGDELEFDDGTYFHCGGNSLYSEYRTCQENPCKHCLDMYVNLVEQYVLYKFKMKKLIDRNKLIDLIEPKYRYNFSDIFKRAFENIEIVFAASVIEIDSTNHVYDLVSKLKLPNKGRVCPGRGLPKTGLLMTILAMIFMNGTSASEEDIWKFLNYMQVYPGRKHFIYREPRKLITQDFVKLKYLEYKQISLSDPPCYRFQWGPKAYTETTKMKVLEFMAKGSGVEPSTFSVQYTEALREENQKTKIRKWYPILAQKHCPGHSHQHVQKVMKPQ", "length": 366 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2ADW8-1", "protein_name": "Predicted gene 15128", "gene_name": "Gm15128", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MANREDEIRQLRYLEAANSEEEYNEENDIQSESSRGQAFFPGHPRGRGHRRDSRGRNGHFFRQRFSANHPLLHLTRQVNLESLTRRNGNQSEERQLQQERIQLFFRSLHGLSQSHDHHIGRSHGHDSRRSRNRFRRAPVQSERSHVYSGRTNNYTDRPQHDLSNRPHNQLSVRPHPDLSGRPLHDYSGRPHQNHAVRLQHGHSDRYHLTHTERVLPNNSGIAHPGHTERDNQVQRGRAHDNQSGLAHHNHDGRSHHDHSGRAYHGHARRAHNNQSWRSDNNQSWRDLNQSWRGQNNQSQRGHDNQSQRGHDNQSRRGHDNQSQRGHDNQSQRGHNDQSWRAHNIRSRRDRYHTSLRSSSIQSWMLHERERYHGPRGRNGPRDASPPGSEPEIDRSSAIRERTDYLWVQEHRRNETVELNVGLEDGYSSAEESDESFDRLTCRSMLDTLY", "length": 449 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2AGW6-1", "protein_name": "PRAME like 22", "gene_name": "Pramel22", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MHRLLREEALAISSLKDLPNMLFPVLFEEAFIFGYTKILKAMIPEWPFPYLSIAVLIDNCNLESLKAVLEGLDILLAQKVHSSRCKLKEISWRDTNHGLDGIRPGSHEVEGLSEFMEQKHPNCVEKKELKVTTELSVMNGRLNESDTYLLEWTQQRKDSIHLFCRKLVIQSLTKATVIEIFKIVNADCIPELELCSLCLEDLAFLNPYLRQMDNLLELTLDHITDSLSIGDSEMLEERMITLVSQLPTFPCLQKLCINDVYFIYGNLKEFLGCLKKPLVSFCISNCELSQSDLDYLPYCLNIFELKCLYIINIHLQYLCLEPLGFLLESVRHTLGCLALKSCNMGEPHFKSLLPALSQCFHLTDVNFQENELSLLSLKQLLQHTSKLTQLSYEMYPAPHECYDDRGVILSHRIEQFCPEVLDMLRAKRQPKDINFVTTQCSKCGIYYVYDLETQRCRFLK", "length": 460 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2AGW7-1", "protein_name": "PRAME like 23", "gene_name": "Pramel23", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNVNSPPTLMKLASQRLLREEALAISALKDLPNMLFPVMFEEAFINGHTKILKAMIPLWPFPYFSLGMMIKNLTLDTLKAVLQEIDILISKVVHSSRCKLKEIKWKNTDYGLQGIWPGSHEFDGLSEFMEQKQPDCGVKKELKVITHLKLMEGSLDECATYLLQWAQQRKDSIHLCCRKLKIQGSINATVIEIFKIVHADCIQELELCCLCLEDLDFLNPYLKQINNLIRLKLDEIKGTVSMGESRNIDEEKVITLISQLPTLQHLEKLCINDVSFIEGNLKECLRCLKKTLEILCITNCYLLQSDLDYLPYCLNILELKCLDFSNIPLSHLFLEHLRFLFERVRHTLECPILKSCEMGESQFNSLLPAISQCCQLTEVNFYDNELSLIFLKKFLHHTAKLSQLTYELYPAPLECYDNRDIILSHRLENFCPELLNILRAKKTAQGGHLCYNPML", "length": 455 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2AHC7-1", "protein_name": "SSX member B14", "gene_name": "Ssxb14", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "METVISCEKIPMEVLHKPKNICKAFQDISTYFSGEEWGKLTEWQKSAYMYMKRNYTRMTGVTVNQPVFMSGKEQAKQSLVKGIEVHDSEDECFEESFGVTPRKRMKLTSVTISIHNVEGSLASGENDSNLAETDGIQVNVWSHRLRERKYRVIYSEISDPEEEEDDDY", "length": 168 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2AK42-1", "protein_name": "Pre-mRNA-splicing factor CWC22 homolog", "gene_name": "Cwc22rt5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKSSVAHMKQSSGHNRRETHSSYCRSSSPEDRYTEQERFPRDRDYSDYSRSDYERSRRGYSYDDSMESRSRDREKRRERERDADHRKRPWKSPSPDRSPARGIRQSSPQEEPTWKKKKDELDPLLTRTGGAYIPPAKLRMMQEQITDKSSLAYQRMSWEALKKSINGLINKVNISNISIIIQELLQENIVRGRGLLSRSVLQAQSASPIFTHVYAALVAIINSKFPQIGELILKRLILNFRKGYRRNDKQLCLTASKFVAHLINQNVAHEVLCLEMLTLLLERPTDDSVEVAIGFLKECGLKLAQVSPRGINAIFERLRNILHESEIDKRVQYMIEVMFAVRKDGFKDHPVILEGLDLVEEDDQFTHMLPLEDDYNPEDVLNVFKMDPNFMENEEKYKAIKKEILDEGDSDSNTDQGAGSSEDEEEEEEEEEEEEEEGEDEEGGQKVTIHDKTEINLVSFRRTIYLAIQSSLDFEECAHKLLKMEFAESQTKELCNMILDCCAQQRTYENFFGLLAGRFCMLEKEYMESFESIFKEQYDTIHRLETNKLRNVAKVFAHLLYTDSLPWSVLECIKLSEETTTSSSRIFVKIFFQELCEYMGLPKLNARLKDETLQPFFEGLLPRDNPRNTRFAINFFTSIGLGGLTDELREHLKNTPKVIVAQKPEAEQKKTALTSSSSESSSASDSSDSDSDSSESSSESSSEASDSSSSSSTQSSTSAKGTRKKRQGKARGEEVDKLARGHQALERRQGGREDQRHQEGRTERARSERHRAQNSRDADWRDSLAKHIDDRSHENSHSRVGNGREQGSHREPEDRHGEPKKKQREKRFFL", "length": 830 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2ANE0-1", "protein_name": "Reproductive homeobox 2F", "gene_name": "Rhox2f", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MERQSINYLLDVGPEEDEENANGVKTLMVLLAGDGRNEGESGRGLPGSGASAAEGYRAGEISAGGPAAQVADLMDDSNQEDLGATACDQEKEKQPEEPVPDSMGDLENVKRVSGPWSTVNPVRVLVPKFRHLWRHSFNVLQLQELESIFQCNHYISTKEANRLARSMGVSEATVQEWFLKRREKYRSYKRL", "length": 191 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2ANE1-1", "protein_name": "Reproductive homeobox 3F", "gene_name": "Rhox3f", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSMKPERSMSNWIHSNVEPAGRNLFQVNGHRSALLPELPQDYHRASRSVNGCETKMDNTQGTKVLPAEEARNEEDGGQVESALGATAARGRGKEALNGESPAAAGTAGLVEEDRNKEDGGTKGGEKNEQEVREQIPEHVEGESDQAEALRQVPRRRLHHRFTQWQLDELERIFRMNYFLSLEARKQLARWMGVNEAIVKRWFQKRREKYRWYKRL", "length": 215 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2ASJ1-1", "protein_name": "PRAME like 14", "gene_name": "Pramel14", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDLEAPPTLLQLAAQCTVRKEVLTISVLQNLPMKLFPPLFKEADILRKAKMIKLLVEYWPYPSLLVGLLIDKTNLETFQAILEGVGTWLKRKYRPRMGKLQVVDLRNGHHDFWDMLAGREGGDQLVETMPEKQEVEGHSRRQRLRVFSDLSFKSSRHEDKQQTHLLQWAKDREGFLHLCCEKLEIGALGVSKVKKVLKLLQPEFIKELELNTVGNLSKLTKLVPCISKMRNLQKLMLVRIFGRHTYTPLEERNVTKILSLFPKLSYLQHLTIDDVYFLRDHMNELFRYLEAPLLSLTITLCQISQSDLESFSQHWNYGQLKHLCLKGVSLSTLNVTPLKFFLESVADTLQTLELEDCRMKDSHLRILLPALTKCTRLTSINFYDNNISRDVLQDLLHRTANMSQLTMELYPAPVEVYNEWSYVQVERFSQLCAELMNTLITVRRPKSVCFGTYSCYDCDTHCIYGNQTTFCECLE", "length": 475 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2ATW2-1", "protein_name": "Olfactory receptor", "gene_name": "Or4x15", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MADIHNVTEFFFLGLSSNQEVQRVCFVIFLFLYMAIVLGNLLMVVIVAVSRNLGSPMYFFLSSLSFVEICYSSTTAPKLIVDLLAEKKSISVWGCMAQLFFMHFFGGIEMFLLMMMAYDRYVAICKPLHYTSIMNRQVCTVLVGMAWMGGFVHSLAQVLLIFRLPFCGPNIIDHYFCDVLPVLKLVCSDTFLIGLLIVVNGGTLTVISFVVLLSSYAVILFHLRTQSAEGRRKALSTCGSHVTVVVIFFAPCVFIYLRPTATLPIDKMVTVFYTVITPLLNPIIYSLRNAEVKKVIKILCTRATKVDKK", "length": 309 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2AWL9-1", "protein_name": "Reproductive homeobox 2C", "gene_name": "Rhox2c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MERQSVNYKLDVGPEEDEENANGIKTLMVLLAGEGRNEGESGRGLPGSGASAAEGYRAGELSAGGLAAPVADLMDNSNQEDLGATGCDQEKEKQPEEPVPDSMGDLENVKRVSGPWSTVNPVRVLVPKFRHGWQQSFNVLQLQELESIFQCNHYISTKEANRLARSMGVSEATVQEWFLKRREKYRSYKRL", "length": 191 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2AWM0-1", "protein_name": "Reproductive homeobox 3C", "gene_name": "Rhox3c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSMKPERSISNWIHSNVERAGRNLFQVNGHRSALLPELPQDYHRASRSVYGCETKMDSTQGTKVLPAEEARNEEDGGQVESALGATAARGRGKEALNGESPAAAGTAGLVEEDRNKEDGGTKGGEKNEQEVREQIPEHVEGESDQAEAPRQVPRRRLHHRFTQWQLDELERIFRMNYFLSLEARKQLARWMGVNEAIVKRWFQKRREQYRWYKRL", "length": 215 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BED8-1", "protein_name": "Predicted gene, 58953", "gene_name": "Samt1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDQLIVDTRSVIYRFINEKDCIYKLSGLLSSLAAFMLEVLIASILSWRLWEFDSNVVQFVSFGLFEAYYPQQFNISGTLTKMLVYTPIDSTWNISTEFMYAQNLVVWAILMKPVVLVFCVMAIKISCTKNPLVEMQIYCYKISALILSVSSMFTFVSVIWNHMVDFYGHTTLDFPSDFPVKKEALTSKHLTVVLPVGLLIATMSLFGVIMFLSEISDLKLKRPVKANDASKMGLLDA", "length": 237 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BEE3-1", "protein_name": "Spermatogenesis associated multipass transmembrane protein 1d", "gene_name": "Samt1d", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDQLIVDTRSVIYRFINEKDCIYKLSGLLSSLAAFMLEVLIASILSWRLWEFDSNVVQLVSFGLFEAYYPQQFNISGTLTKMLVYTPIDSTWNISTEFMYAQNLVVWAILMKPVVLVFCVMAIKISCTKNPLVEMQIYCYKISALILSVSSMFTFVSVIWNHMVDFYGHTTLDFPSDFPVKKEALTSKHLTVVLPVGLLIATMSLFGVIMFLSEISDLKLKRPVKANDASKMGLLDA", "length": 237 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BEI6-1", "protein_name": "Myb/SANT DNA binding domain containing 5 family member 10", "gene_name": "Msantd5f7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MQREDNRVQSVRSDKEANRRRRLRQEGQSSSGPCDSPWTEDEIWILLQEWAMVEYELGDPGNKMHAKAKSLSRRLSNRGLRKSKNSCLDVMVKMKDLHTRLCNERPRAYRLYSTYEWILYEILGHPRSQGGYVPGLWFDGHSKPPASYAPSLCIGGAISPGPSFSPWTDPEIKIFLQEWQVVEREIGHPGQKIKQKSSLVCQRLYHRGLFKDIQSCLDLMWTLKDLHSTLSRERSRTVPLFSPYRDYLERIFDPKCQRGHVPGALYNWSGYHRPSSSPQTPMVMPSPVYQPWDYGMSASSGQLHGNPSLIMSSQDSLVPRWDAWNATYPLPVQHVLLASLSGDNNFQLAWSPRDESSSPQ", "length": 360 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BEI8-1", "protein_name": "Myb/SANT DNA binding domain containing 5 family member 8", "gene_name": "Msantd5f8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MQREDNRVQSVRSDKEANRRRRLRQEGQSSSGPCDSPWTEDEIWILLQEWAMVEYELGDPGNKMHAKAKSLSRRLSNRGLRKSKNSCLDVMVKMKDLHTRLCNERPRAYRLYSTYEWILYEILGHPRSQGGYVPGLWFDGHSKPPASYAPSLCIGGAISPGPSFSPWTDPEIKIFLQEWQVVEREIGHPGQKIKQKSSLVCQRLYHRGLFKDIQSCLDLMWTLKDLHSTLSRERSRTVPLFSPYRDYLERIFDPKCQRGHVPGALYNWSGYHRPSSSPQTPMVMPSPVYQPWDYGMSASSGQLHGNPSLIMSSQDSLVPRWDAWNATYPLPVQHVLLASLSGDNNFQLVWSPRDESSSPQ", "length": 360 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BFR3-1", "protein_name": "Histone H2A", "gene_name": "H2al1j", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAKKMQRRRRQKRTHSQRGEFPLSLVDRFLPEGNHSGRLSSSAPVILDSVLEYLSSNILELAGEVAYTTGRKRIAPEDVGLVVQNNEQLCQLFKPGATSVFDPPEPDDN", "length": 109 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BFZ7-1", "protein_name": "BTB domain containing 35, family member 9", "gene_name": "Btbd35f11", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGKTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BH64-1", "protein_name": "Secretoglobin, family 1B, member 30", "gene_name": "Scgb1b30", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKLTGALLLLGAALLLTSEGDCGLCPVLQKKVHKFFDGTTEEYVEYLKQYNNDPLVLENAANIKKCSDRMLAEEDKTQATNFINKVTGSRSC", "length": 92 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BHG6-1", "protein_name": "BTB domain containing 35, family member 7", "gene_name": "Btbd35f7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLSCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYRDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSFGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BI40-1", "protein_name": "X-linked lymphocyte-regulated 4A", "gene_name": "Xlr4a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASKIKGRPPKQPKVTPALPSDDSQQLHENNPGNNLALETCGESSSSHGTGGPKPGPSKKTLNERKRKYGVSVNKTVQNIEWNVDHFLKVQHERRQELYKDYSHQFLTLVMMWNIDVDQIKKQAGKLSDILDEQQKLFQQFQSIHMQKIEEFKELCDRHLKNLQAIKCCRRKAIIEEARKLMDYLEKTVTEETVHVNKQEAKDGVQSSLLSLLIS", "length": 215 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BI45-1", "protein_name": "X-linked lymphocyte-regulated 5A", "gene_name": "Xlr5a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSNKEQKAMKKSGKHQRVHKTLPSDDFKNSDEVNPADKPAVGTSGMGSHSSGSDMQEAREPVQKKMQDFKGDDGTGLLMEKKKQFEEDVNASFRSLNENLQSILKAQQNSRQELKSLYCERFGSVYHNWLVEMDRTRDQEEYFSFITQQQMKILQTAIEDHETKLKNAKDMCDTFLKKANDLSKRQKTFIGGQHTIVEKEISKVQNRVIMETQDQDISMVETYLQSLIHESSEETI", "length": 236 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BI50-1", "protein_name": "X-linked lymphocyte-regulated 5B", "gene_name": "Xlr5b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSNKEQKAMKKSGKHQRVHKTLPSDDFKNSDEVNPADKPAVGTSGMGSHSSGSDMQEAREPVQKKMQDFKGDDGTGLLMEKRKQFEEDVNASFRSLNENLQSILKAQQNSRQELKSLYCERFGSVYHNWLVEMDRTRDQEEYFSFITQQQMKILQTAIEDHETKLKNAKDMCDTFLKKANDLSKRQKTFIGGQQTIVEKEISKVQNRVIMETQDQDIAMVETYLQSLIHESSEETI", "length": 236 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BI74-1", "protein_name": "SSX member B6", "gene_name": "Ssxb6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "METVSSCEKIPMEVLYEPKNICKAFQDISTYFSDEEWVKLTQWQKSAYVYMKRNYIRMTDLGVTVNQPVFMRGKEQAKQSLVEGIEIHDSDDECFEGSFGVTPIKRMKLTSVTISIHNVEGSHDSGENDSNLAETGGIQVNVWSHRLRERKYRVIYSEISDPEEEEDDDY", "length": 170 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BIM8-1", "protein_name": "Major urinary protein 18", "gene_name": "Mup18", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKMLLLLLCLGLTLVCVHAEEASSTGRNFNVEKINGEWHTIILASDKREKIEDNGNFRLFLEQIHVLENSLVLKFHTVRDEECSELSMVADKTEKAGEYSVTYDGFNTFTIPKTDYDNFLMAHLINEKDGETFQLMGLYGREPDLSSDIKERFAQLCEEHGILRENIIDLSNANRCLQARE", "length": 181 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2CEK7-1", "protein_name": "Major urinary protein 14", "gene_name": "Mup14", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKMLLLLCLGLTLVCVHAEEASSTGRNFNVEKINGEWHTIILASDKREKIEDNGNFRLFLEQIRVLENSLVLKFHTVRDEECSELSMVADKTEKAGEYSVTYDGFNTFTIPKTDYDNFLMAHLINEKDGETFQLMGLYGREPDLSSDIKERFAQLCEEHGILRENIIDLSNANRCLQARE", "length": 180 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2CG71-1", "protein_name": "BTB domain containing 35, family member 19", "gene_name": "Btbd35f20", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLQPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGKTWCLHKVFLCQSVYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKMRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTLKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2CG92-1", "protein_name": "BTB domain containing 35, family member 10", "gene_name": "Btbd35f10", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIHALGKTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2CGC2-1", "protein_name": "BTB domain containing 35, family member 3", "gene_name": "Btbd35f4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQRMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGKTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 496 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A3KG49-1", "protein_name": "PWWP domain containing 4C", "gene_name": "Pwwp4c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDSSEYVLCGWKSQLCPARVLSRPRTPAHSKRRGVPFLEVQILPVGEKRRVRSSKVRPLAKSEIISINSLAGKESRGRGSPGQTRASRRALKVALDGLGEGSSFFQGGRAGSRRTSTLAPKVPKEQASSSSSSLGQRLRLRLRQLLPLSLCQRLHLHLRLRLHLHMHLCLQGRNQKGQGLSQRSPGKRVRPDPGPVMMGSQNVPAVPVGEAQAHTAAGLPRSEVEGDVLRGTRVWPSYSKKTPLGKAGGNPGKRKPGTGKRKLRSLSAPASRKGTRSKTEQQAASGPPRHISISPKALKQRVRCAGLEIRAAGAQRKTALAENKDHPGLGTPKPDSKRASAACMPPVLRLRRSLRIASRKKKTHVLCALCGLPEWEPQVHSKVTNTRFKRRGARVQKDAKATNVVSAQEPSTIEQGTLVWFKFQDLPFWPAVVKSVSKIDKMARVLLIEGNMQFERRGIRVPLRKLKHLDCGEKVSLVRRASRLYAQGINWCFSVIDHYREGLSRGSLLGSFMDYYTTQASYPLRRAVQEGDLHIDFPKVSYAELEDWEEETALGGKGPYKKLLPDRMRAAWDRANQKLVDFIVKRKGADQHLLDIVKGRKPSRWLDDLWKSKREVFCIETYLEDDDQLHLVARHLQEVAKEADEALLSLARGDKVRFTMEVLFPEAIIYSIAALDELSYKEAEEKYLRGPPVHYREKELFDKTILKAARKRSAARIRAARDPPVPTP", "length": 728 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A5WVZ0-1", "protein_name": "2.7.1.138", "gene_name": "cerk", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEKQSTLLCSELSVQRRLYEVTLNCAILAWKDVQNAKKHTGRAIYGAVKAGSHCVPVCEIIAVQEKEDDSPCKDTGKWQKVPQSPTDSCQHAFTVYYVERTRQHCWRCSNVTFQYSEHSLCLLWIQTIKEQLALLSAQSTEELAGVHQPLRRKTTRQADLRPQSGPHLFPGFHFHRRDWPHSFSAHPSELRFYIIADGKEPVMKCTGDCFSPRVQLHHLMQLIDGLHQASRKMQFNCQMNIMMFLPPLYHQPGNNGFSLFVSIVTEHANHARDHLKAEADLKKYDGVVCVGGDGMFSEIMHGLVSRTQQDAGVDENSTEETLIPCGLRIGIIPAGSTDCICYATVGSNDPVTSALHMVVGDSQPMDVCSVHSDDRFLRYSVSLLGYGFYGDVLKDSERKRWMGPARYNISGVKTFLSHRYYEGTVSFLPAEENLGTPRDKVQCRSGCSICRRSSSDKLLSKEDEASVSDVDCRDTWTVIRGKFLAINAANMSCACPRSPKGLSPSAHLADGTTDLILVRKCSRVDFLRHLLRHTNKKDQFDHSFVEVYRVKQFRFTPRFQECGSEMDLRESRAGGKHFFCQICRENRACGCMSSQSNWNCDGEILPHTAIQVRVHCQLIKLFARGIEEQPVFEDLYAHCQLNNPPNHEP", "length": 649 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A5WWD5-1", "protein_name": "alpha-1,2-Mannosidase", "gene_name": "man1b1b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLPSTRKDFVSLTLSESGSYSNSKQWRRQSCWRKWKQLSRLQRSLILLTLMLLLVCGIATSPTLIGHWRGMNGDDVKNSFVVDLKNEYRSILPEPPSERKDFDRRGAFGLEKLLQGKVNVSGVLGDQNHGLDLKNADKGSEGQKPIISWRGAVIEEEQASDTDTKDTENQGDPASLALAESRLEAVREAFRHAWKGYKDFAWGHDELKPISKSYGEWFGLGLTLIDALDTMWILGLQEEFAEAREWVAKELSFDKNVDVNLFESTIRILGGLLSTYHLTGDNLFLDKAKEIGFRLMPAFSTPSKIPYSDVNIGKGTAHPPRWTSDSTVAEVTSIQLEFRELSRLTGDPKYKLAVMEVMKQVHKLDGKQDGLVPMFINTNNGLFTHQGIYTLGARADSYYEYLLKQWIQGGRIEQELLEDYLQAVEGVKKNLLKKSTPLGLTFVGELSHGHFSPKMDHLVCFLPGTLALGVHYGLPADHMELAKQLIETCYQMYAQMETGLSPEIAHFNMHDGSTQDVDVKIADRHNLLRPETVESLFYLYRLTRDKKYQQWGWEILQNFNKYTRVPTGGYTSINNVRDPSYTSPRDKMESFFLGETLKYFYLLFSEDPTLISLDKYVFNTEAHPLPVWPQAE", "length": 632 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A6NCW0-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 3", "gene_name": "USP17L3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGDDSLYLGGEWQFNHFSKLTSSRPDAAFAEIQRTSLPEKSPLSSETRVDLCDDLAPVARQLAPREKLPLSSRRPAAVGAGLQNMGNTCYENASLQCLTYTLPLANYMLSREHSQTCQRPKCCMLCTMQAHITWALHSPGHVIQPSQALASGFHRGKQEDVHEFLMFTVDAMKKACLPGHKQVDHHSKDTTLIHQIFGGCWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVKQALEQLVKPEELNGENAYHCGLCLQRAPASNTLTLHTSAKVLILVLKRFSDVAGNKLAKNVQYPECLDMQPYMSQQNTGPLVYVLYAVLVHAGWSCHDGHYFSYVKAQEGQWYKMDDAEVTVCSITSVLSQQAYVLFYIQKSEWERHSESVSRGREPRALGAEDTDRRAKQGELKRDHPCLQAPELDEHLVERATQESTLDHWKFLQEQNKTKPEFNVGKVEGTLPPNALVIHQSKYKCGMKNHHPEQQSSLLNLSSTTRTDQESMNTGTLASLQGRTRRAKGKNKHSKRALLVCQ", "length": 530 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A6NCW7-1", "protein_name": "Inactive ubiquitin carboxyl-terminal hydrolase 17-like protein 4", "gene_name": "USP17L4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGDDSLYLGGEWQFNHFSKLTSSRPDAAFAEIQRTSLPEKSPLSSETRVDLCDDLAPVARQLAPREKLPLSSRRPAAVGAGLQNMGNTCYENASLQCLTYTLPLANYMLSREHSQTCQRPKCCMLCTMQAHITWALHSPGHVIQPSQALAAGFHRGKQEDVHEFLMFTVDAMKKACLPGHKQVDHHSKDTTLIHQIFGGCWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVKQALEQLVKPEELNGENAYHCGLCLQRAPASNTLTLHTSAKVLILVLKRFSDVAGNKLAKNVQYPECLDMQPYMSQQNTGPLVYVLYAVLVHAGWSCHDGYYFSYVKAQEGQWYKMDDAEVTVCSITSVLSQQAYVLFYIQKSEWERHSESVSRGREPRALGAEDTDRPATQGELKRDHPCLQVPELDEHLVERATEESTLDHWKFPQEQNKMKPEFNVRKVEGTLPPNVLVIHQSKYKCGMKNHHPEQQSSLLNLSSMNSTDQESMNTGTLASLQGRTRRSKGKNKHSKRSLLVCQ", "length": 530 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A6NDS4-1", "protein_name": "TBC1 domain family member 3B", "gene_name": "TBC1D3B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDVVEVAGSWWAQEREDIIMKYEKGHRAGLPEDKGPKPFRSYNNNVDHLGIVHETELPPLTAREAKQIRREISRKSKWVDMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNIEEMKLKNPGRYQIMKEKGKRSSEHIQRIDRDISGTLRKHMFFRDRYGTKQRELLHILLAYEEYNPEVGYCRDLSHIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQEHVVATSQSKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQALMPITRIAFKVQQKRLTKTSRCGPWARFCNRFVDTWARDEDTVLKHLRASMKKLTRKQGDLPPPAKPEQGSSASRPVPASRGRKTLCKGDRQAPPGPPARFPRPIWSASPPRAPRSSTPCPGGAVREDTYPVGTQGVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDVEGPWFRHYDFRQSCWVRAISQEDQLAPCWQAEHPAERVRSAFAAPSTDSDQGTPFRARDEQQCAPTSGPCLCGLHLESSQFPPGF", "length": 549 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A6NJZ7-1", "protein_name": "RIMS-binding protein 3C", "gene_name": "RIMBP3C", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAKDSPSPLGASPKKPGCSSPAAAVLENQRRELEKLRAELEAERAGWRAERRRFAARERQLREEAERERRQLADRLRSKWEAQRSRELRQLQEEMQREREAEIRQLLRWKEAEQRQLQQLLHRERDGVVRQARELQRQLAEELVNRGHCSRPGASEVSAAQCRCRLQEVLAQLRWQTDGEQAARIRYLQAALEVERQLFLKYILAHFRGHPALSGSPDPQAVHSLEEPLPQTSSGSCHAPKPACQLGSLDSLSAEVGVRSRSLGLVSSACSSSPDGLLSTHASSLDCFAPACSRSLDSTRSLPKASKSEERPSSPDTSTPGSRRLSPPPSPLPPPPPPSAHRKLSNPRGGEGSESQPCEVLTPSPPGLGHHELIKLNWLLAKALWVLARRCYTLQEENKQLRRAGCPYQADEKVKRLKVKRAELTGLARRLADRARELQETNLRAVSAPIPGESCAGLELCQVFARQRARDLSEQASAPLAKDKQIEELRQECHLLQARVASGPCSDLHTGRGGPCTQWLNVRDLDRLQRESQREVLRLQRQLMLQQGNGGAWPEAGGQSATCEEVRRQMLALERELDQRRRECQELGTQAAPARRRGEEAETQLQAALLKNAWLAEENGRLQAKTDWVRKVEAENSEVRGHLGRACQERDASGLIAEQLLQQAARGQDRQQQLQRDPQKALCDLHPSWKEIQALQCRPGHPPEQPWETSQMPESQVKGSRRPKFHARPEDYAVSQPNRDIQEKREASLEESPVALGESASVPQVSETVPASQPLSKKTSSQSNSSSEGSMWATVPSSPTLDRDTASEVDDLEPDSVSLALEMGGSAAPAAPKLKIFMAQYNYNPFEGPNDHPEGELPLTAGDYIYIFGDMDEDGFYEGELDDGRRGLVPSNFVEQIPDSYIPGCLPAKSPDLGPSQLPAGQDEALEEDSLLSGKAQGMVDRGLCQMVRVGSKTEVATEILDTKTEACQLGLLQSMGKQGLSRPLLGTKGVLRMAPMQLHLQNVTATSANITWVYSSHRHPHVVYLDDREHALTPAGVSCYTFQGLCPGTHYRVRVEVRLPWDLLQVYWGTMSSTVTFDTLLAGPPYPPLDVLVERHASPGVLVVSWLPVTIDSAGSSNGVQVTGYAVYADGLKVCEVADATAGSTVLEFSQLQVPLTWQKVSVRTMSLCGESLDSVPAQIPEDFFMCHRWPETPPFSYTCGDPSTYRVTFPVCPQKLSLAPPSAKASPHNPGSCGEPQAKFLEAFFEEPPRRQSPVSNLGSEGECPSSGAGSQAQELAEAWEGCRKDLLFQKSPQNHRPPSVSDQPGEKENCYQHMGTSKSPAPGFIHLRTECGPRKEPCQEKAALERVLRQKQDAQGFTPPQLGASQQYASDFHNVLKEEQEALCLDLRGTERREERREPEPHSRQGQALGVKRGCQLHEPSSALCPAPSAKVIKMPRGGPQQLGTGANTPARVFVALSDYNPLVMSANLKAAEEELVFQKRQLLRVWGSQDTHDFYLSECNRQVGNIPGRLVAEMEVGTEQTDRRWRSPAQGHLPSVAHLEDFQGLIIPQGSSLVLQGNSKRLPLWTPKIMIAALDYDPGDGQMGGQGKGRLALRAGDVVMVYGPMDDQGFYYGELGGHRGLVPAHLLDHMSLHGH", "length": 1639 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A7TZG3-1", "protein_name": "Selection and upkeep of intraepithelial T-cells protein 9", "gene_name": "Skint9", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MESSASCLPGFFMSFLLLQNTVLTQAMRSDIKINIQVPDTEGLLLECTSGSLIPPAEMTWRDSNGNIIPHSTAFNSQDRDGLLYLKSSILLKNRAKGPITCSIYNVTTNQEKKRSIVLPDALFKSENMSLMSNKFSCPSIYLITIIFLNFLRGILVFCCLRRKPVCFRNLMSTVMEALYSKMGVCCLLIWECLLLVLYIAFLPIYVSFRSRAFLLDDTYPLYTNWLWNICIILTVIMVLFPGLILCLLWTLNCYGQVSSLPPTSMELSTKDSEQNSSKSDDSQENYDVNCKILETCESKIFSQHQESCEDDTASTLFIS", "length": 319 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A7XV14-1", "protein_name": "Selection and upkeep of intraepithelial T-cells protein 11", "gene_name": "Skint11", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEPSASCLPGFFMVCILLKITVLTQVMSLDIQINTQIPDTEEGVLVECTAESLFPPAEMTWRDSKGNIIPPSSTFDSQDRAGLLCLKSTILLKNRTEGPITCSIYNKTTNQEKRRSIILSDVLFRPQYMSLMSNNLLYLGIYLIFILFLNFLKGILFCLTKRLVHFRKRMIKIKKVWSNKTRACCPLIWEFLEIVLFIAFLPLYLMFRIRVFTLDEAHILYNNWLWKVCKTLIAMMILFTVLILFLLWTLNRYGKMPCLSSMNIDVSTHDAEQNSSKSAKFQENYDVAGQMILETYEETIFCQHQESCEEYNYDPLLLSSLDALGTCEDEKFSQHQESFEEDEDLQSFSDFKIELYSKLGNLTH", "length": 364 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "B0BMZ6-1", "protein_name": "Cilia- and flagella-associated protein 119", "gene_name": "Cfap119", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MITPRSSQSLEMKVQTELEHSPKLQEEPDRSPSLVDSSVIRIGTDEQNESPAEATSSPVEVAEDPGANLFPPPLPQPRICMWKYLDIHSMHRLEKAATVEEMREVLAELLELGGPEQSLRDAIILDLFSHALIFCRQQGFSLEQTSAACALLQDLHKACVATPLGNVEECYRYFTSVLFCHGVRRPPFSIDLFKEEQLLALADYVVNTYFRHFKLYKYVFTPQVRLDLSLSYMGLQSLHLWPEEKEDEEATVEQAATPQEEEPEAVTEAEQQPSEVCILQTYIKCQLNKELRQLQQLVEERLKESEERLSNRLAALERPYQTPPSKGKSKAK", "length": 332 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "B0G0Z9-1", "protein_name": "Probable polyketide synthase 6", "gene_name": "pks6", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNNLKNIDLIEKGVAIVGIGFRIPSGNNENSICSPDDLFNNLKNGFDGVSSTSERWSDNYHKLGEISSPNAGLLPLNEWKSFDPLFFGINPSEASLIDPQQRLLLKCTWEALEDASIDPISIRGTNTSVFIGASNIDYQHTNKHQDSVLKNAIAQSTCAISNRISYCFDFNGPSLSIDTACSSSLNAVSQGYHSILNGTSDISIVGGVNLILDVEMTKAYSYLSMLSKTHGKCKAFDESGDGFTRGECVGVVVLKNLQDAIKDGNRIYCVINGSSSNVDGNGNMDKVNFYSPSKQSQFNNINSAFKSTNDKLSINDIQYIEAHGTGTKTGDPIETEAISMAFKNRDKSAPILIGSIKSNIGHCEAGSGVASLIKCCLMFKYQCFLPNIHFKNPNPLIKFNEWNLKVVTSPIPFNKRNNEKPVSMMINNFGVTGSNCCLLISEFKNNNNFKENINLESQSVNDRVLIPFSANSSNSLNQYQSKFKNIINNQFNFIDFTAIQIYSKSNYLYQRSVVIASNSNELFENISNKKQIQTKNSIISNMSFKGKNPITIFVFSGQGSQYPKMALELYNNEVIFKKSIDLIDSKLSKYYGFSVWEKVKTIKDDDLTSIHDPIFAQPALCMISVSLFELYYHWGVNPSFILGHSLGEISASYCSGMIDLDTFCYTVYQRSIAQSKTNGCGRMLSINISDEEFKSMYSQKYPQIEIACYNSPQSIVVAGNESILNEISKELKEKEIFTAMLGSLSSFHTSSQQSTKDSILQLNIESNQPKVPIFSTVTTNLFNESNRFNSQYVYDNIIKPVKFTQTISNIYKHIESNQLDNDIVFIEIAPHPTLSFYIKQMVPSSLNESVSVYSALHKKKNDVEEFQQTISNLYCQNGYNINFKCQFNNKKSNLNIELPLYQWSDELYFAQNQVLEQHRKGGPPIDHLGLSNSYYSPFKNSYKTLIDINYKPFQYLKGHMVKGKYYFPGCGYIDNIIQLYKNQDIFISFIEFKTPLILIEGINQYLQTNIQQTGKSEYRAQFHFKDHKSNEWIQSSNSNFQLLDHGNDIPSNYNIKEIIKNKCNLSKLTKNELYKNIKSKTGLNYTGVFQGVTECYIGDNCTLSVVSLESQTNSFLNIPILDTCLHGMLILINDQCQIVFDKAIGFKYYSSNIPADFKENKDSFYVYSNLRPRVGGDSYHGTIIVMLSDGSVLYEIEEVVCKSLIPIKDSLKIEYPNDELYKVHLQSKDSPIPTPSSFKSIIYENDFFQSSLNIPEDLFKYISTLFYKDIIKRCPEININKINSHSVNEIISSFSKISKHERLFRFVFETIKENGILNSFEEKDDTYFEFNKVIIKSSRIISKLLFPLENDNDNEDLPQSLFQNGLMDKIYKCSYLRKKNQVISHVIKHSIKEIINNNIIIRILEFGGGTASLSVEVIEEIVTLLQENPNYQVEIEYTWSDISPAFIADAKNKINKIINDAAITNGLNVIYHPLTIGESLIETQSIKPSYYDFVIMSNVLHVVKDIKQAVEQMYQLLTTNGQLVFLEPPYKSVLNDSIVGSFEQWWSFTDTDIRKDRCGMPQQSWYQLLNSCNFKDIVMSKECIFFGSVIQAQKPPISLLNSQPKYDNIIIYGGSINSSFVENIKLDSNSKSLFQIETIQEFNKLISKSTITNDSIVYFIKTLETLSLDNFKQITLEYIEINQKLLQINSLCKHVLIVSDSRKTNYLASSAIGAARYFDEFPLLKLHTLDFDYDSTQNYINSKNNKMVQFINILTDSKTNVHKEMIIINNKVYYEIVQKEKNLKLKYNSESFENQNNLMCSLSPNLEYQLQSKQIKLRDNQVEVKTIATGINYKDYLNFSGSNSNGDDNTGLPQFGYEFSGIITRVGNNVKDYKVGDNVFGLSNSCTSSHIVTNFKKIQIKPSKISHIEASSIPIDYLTSFMSLFNVGSLNIEDNESILIHLGRDGFGLSTFEILKWKGFKSNLFVTVNSDKTKQYLLKKYGDLITGIYSNTDKSYVAEIKNKLIKLGSKKKGVDLILNTLPSDFMDSNFKLLTKYGRIIDLNSNHLNQSEFLKNINFKYNHGYHNFELSLFQKNKILKCLNEISNAIENGELKTIPIKEFTNLNIKDAIKYITNGNIEKITVSHDHEIYSDIIYRYLDEKEFSILKSNYQINSNNLGKNILITGQSGIILEILKWIIKYSNINTIENVIILSRSSLKWELELLINQTKLSNNNIKFHFKSVDVGDSEQVDNAINDILNENQQIRNIDSIFHFAFQQIACKVQEINMKHLNISHGAKSMGAINLHNQSIKRNWKLINFVMASSALSFIDSTDQCTYACANTLLDSFSKYRVSLGLPSTCINLGLIESTGFVSKNESISVFLDGNGIIPTPINRVLGLLDLQIQNASKFTNSMISNFKPSKFKNNQQISLFLKFDYLMNLKNNSEQTKKENTGNKNIDELFIEKVSELFSMDESKINKNLRLIDYGADSLIIVQLKNWIDKEIGINLITIQQLQNNTINISIKMILNSLMKNNQNKYLPSNRIDYWKNEMKFEESIKPIPNEIRSRNNNSGKIILLTGTTGFLGGFLLFNMLRLDSCKLIYCLIRNKSKSSYPLDEIINNLKYHQLYEKLNKSQISKIIPIIGDLSMNKLGLSNDDYETISKNVNLIINPGADINQKSSYQDCKLVNVNGVKEIIKLSLSSLKQRIPIVNFSSFSVFFNQSLDKNFDESVLPSIDNIDNLPTEYMKSKVVGEYILLEASKNYNIPSILIRPPSIFLNPETGIGHSSDLTLLMIQSCYELGYCPNQILNGFILINTITWLSNNITNIIMNDNCWTNSKMNIYNVHGKQIQSSLIIKPLEKHFNCKQINNNDWIDMVNNSNKKSCIKLKSFHSLENIFKSENKGYKSNESQSISLSTKSLLESMGSYNTDLKITDKMIISHIKHIFK", "length": 2924 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "B0G100-1", "protein_name": "Probable polyketide synthase 7", "gene_name": "pks7", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNNFKNINLIEKGVAIVGIGFRIPSGNNENSISSPDDLFNNLKNGFDGVSSTSERWSDNFHKLGEISSPNAGLLPFNECKSFDPLFFGINPSEAPLIDPQQRLLLKCTWEALEDASIDPISIRGTNTSVFIGSSNIDYLHTNKHQDSVLKNVIAQSTCAISNRISYCFDFNGPSLSIDTACSSSLNAISQGYHSILNGTSDISIVGGVNLILDVETTKAYSYLSMLSKTHGKCKAFDESGDGFTRGECAGVVVLKNLQDAVKDGNRIYCVINGSSSNVDGNGNMDKVNFYSPSKQSQFNNINSAFKSTNEKLSVNEIQYIEAHGTGTKTGDPIETEAISMAFKNRDKSTPILIGSIKSNIGHCEAGSGVASLIKCCLMFKYQCFLPNIHFKNPNPLIKFNEWNLKVVTSPIPFNRKNEKPVSMMINNFGVTGSNCCLLISEFKKQDYEPYENNYKSNNKNILIPFSANSSNSLNQYQSKFKNIINNQFNFIDFTANQIYSKSNYLCQRSVIAASNSNELFEKILNKKQIQTKNSIISNMSFKGKNPITIFVFSGQGSQYPKMALELYNNEVIFKKSIDLINSKLSKYYGYSVLEKLRSIGDDDTTSIHDPNISQPAVCMISVSLFELYCHWGVNPSFILGHSLGEISASYCSGMIDLDTFCYTVYHRSIAQTKTHGNGRMLSINISDEEFKSMYSQKYPQIEIACYNSPQSIVVAGNESILNEISKELKEKEIFTAMLGSLSSFHTSSQQCTKDSVLKLNIQSNQPKVPIFSTVTTNLFNESNRFNSQYVYDNIINPVRFTQTISNIYKHIESNQLNNDIVFIEIAPHPTLSFYIKQMVPSSLNESVSVYSALHKKKNDVEEFQQTISNLYCQNGYNINFKCQFNNKKSNKKIDLPLYQWSDETYFAQTQTLEQHREEGPPIDHLGISNSFISPFNNSYKTLIDINNKPFQYLKGHMVKGKYYFPGCGYIDNIIQLYKNQDIFISFIEFKTPLILIEGINQCLQTNIQQTGKSEYRAQFHFKDQKSNQWTQSSNSNFQLLDHGNDIPSNYNIEEIIKNKCNLSKLTKNELYTHIKSKTGLNYTGVFKGVTECYIGDNCSLSVVSLESQTNSFLNIPILDTCLHGMLVLINDQCQIVFDKTIGFKYYSSNIPAYFKENKDCFYVYSHLKSKSADSYHGSIIVMLSDGSVLYEIQEVVCKSLIPIKDSLKIEYPNDELYKVHLQSKDSQIPTPSYFKSIIYENDSFHSIVNIPEDLFKYISTLFYKDIIKRCPEININKINSHSVNEIISSFSKISKHERLFRFVFETIKENGILNSLEENDDAYFEFNELVIKSSRIISKLLFPLENDNDNEDLPQSLFQNGLMDKFYKCNNFKKKNQIISHVIKHSIKEIINNNIIIRILEFGGGTASLSVEVIGEIVTLLQENPNYQVEIEYTWSDISPAFIADAKNKINKIINDAAITNGLNVIYLPLTIGESLIETQSIKPSYYDFVIMSNVLHVVKDIKQVVEQMYQLLTPNGQLVFVEPPYKSILIDSIVGSFDQWWSFTDTDIRKDRCGMSQQSWYQLLKTCNFKDIVMSKECIFGSVIQAQKPPISLLNSQPKHDNIIIYGGGNNSRFFENIKLYSNSKSLIQIETIQEFNQFINKSTITNDSIIYFIKTLETLSLDNFAQITLEYIEINKKLLQINSLCKHVLIVSDSRKTNYLASSVVGAARYFDEFQQLKLHTLDFDYDSTQNYINSKNNKMVQFINILTDSKTNVHKEMIIINNKVYYEIVQKEKNLKLKYNSESFENQNNLMCSLSPNLEYQLQSKQIKLRDNQVEVKTIATGINYKDYLNFSGSNSNGDDNTGLPQFGYEFSGIITRVGNNVKDYKVGDNVFGLSNSCTSSHIVTNFKNIQLKPSKISHIEASSIPIDYLASFISLFNVGSLNIEDNESILIHLGSDGFGLSTFEILKWKGFKSNLFVTVNSDETKQYLLDRYGDFISGIYSNTDKSYVTEIKNELIKLGSKKKGVDLILNTLPSDFMDSNFELLTKNARIIDLTSNHLNQSEFLKNINFKYNHSYHNFQLSLFQKNKIQKCLNEISNAIENGELKTIPIKEFTNLNIKDAIKYITNGNIEKITVSHDHEIYSDIIYRYLDEKEFSILKSNYQINSNNLGKNILITGQSGIILEILKWIIKYSNINTIENVIILSRSSLKWELELLINQTKLSNNNIKFHFKSIDVGDSEQVDNAINEILNENQQITNIDSIYHFAFQQITCKVQEINMKHLDISHGAKSMGAINLHNQSIKRNWKLINFVMASSAISLIGSTDLCTYACANTLLDSFSKYRVSLGLPSACINFGSIESTGFVSKNESVSVFLDGGGFHPTPINQVLGLLDLQIQNSGKFTNSMLSNFKPSKFKNNQQISLFLKFDYLMNLKNNSEQTKKENIGNKNIDELFIEKVSELFSTDESKINKNLRLIDYGADSLIIVQLKNWIDKEIGINLITIQQLQNNTINISIKMILNSLMKNNQCGREI", "length": 2513 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "B0G101-1", "protein_name": "Probable polyketide synthase 8/35", "gene_name": "pks8", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNNLEIINLIDKGVAIVGVGFRIPSGNNENSICSPDDLFNNLKNGFDGVSSTSERWSDNFHKLGEISSPNAGLLPFNECKSFDPLFFGINPSDAHQIDPQQRLLLKCTWEALEDASIDPISIRGTNTSVFIGSSNIDYQHINKHQDSVLKNVIAQSAYAVSNRISYCFDFNGPSLSIDTACSSSLNAVSQGYHSILNGTSNMSIVGGVNLILDVGMIKAYSYLSMLSKTHGKCKAFDESGDGFTRGECATIVVLKNLQDAVKDGNRIYCVINGSSSNVDGGGHMDKVNLYSPSKQSQFNNINSAFKSTNGKLSINDIQYIEAHGTGTKTGDPIETEAISMAFKNRDKSTPILIGSIKSNIGHCEAGSGVASLIKCCLMFKYQCFLPNIHFKNPNPLIKFNEWNLKVVTSPIPFNKRINEKPVSMMINNFGVTGSNCCLLISEFKKQDYESYENNNNNKSNHKNILIPFSANSSNSLNQYQSKFKNIINNQFNFIDFTANQIYSKSNYLYQRSVVIASNSNELFEKILNKKQIQTKNSIISNMSFKGKNPITIFVFSGQGSQYPKMALELYNNDEIFKKSIDLIDSKLSKYYGYSVWGKLTTIKDDDLTSIHDPIFAQPALCMLSVSLFEIYCHWGVNPSFILGHSLGEISAAYCSGMIDLDTFCYTVYYRSIAQSKTNGCGRMLSINISDEEFKSMYSQKYPQIEIACYNSPQSIVVAGNESILNEISKELKEKEIFTAMLGSLSSFHTSSQQCTKDSILQLNIESNQPKVPIFSTVTTNLFNESNRFNSQYVYDNIIKPVKFTQTISNIYKHIESNQLNNDIVFIEIAPHPTISFYIKQMVPSSLNESVSVYSALHKKKNDVEEFQQTISNLYCQNGYSINFKCQLENKKSNQSINLPLYQWDDELYFAQTQTLEQYTKEGPPIDHLGLSNSYYSPFKNSYRTFIDINNKPFQYLKGHMVKGKYYFPGCGYIDIIIQLYKNQDIFISFIEFKTPLILIEGINQYLQTNIQQTGKSEYRAQFHFKDQKSNEWIQSSNANFQLLDHGNDIPSNYNIEEIIKNKCNLSKLTKNELYTQIKSKTGLNYTGVFQGATECYLGNDCSLSVLSLKSQTNSFLNIPILDTCLHGMLVLINDQSQIVFDKAIGFKYYSSNIPSDLKEYKDSIYVYSNLKPKNADSYHGSIIVMLSDGSVLYEIQEVIFKSLIPIKHSLKIEYPNDELYKVHLQSKDSQIPTPSSFKSIIYENDFFHSALNIPEDLFKYISTLFYKDIIKRCPEININKINSHSVNEIISSFSKISKNQRLFRFVFETIKENGILNSLEENDDAYFEFNELVIKSSKIISKLLFPLESDNDNEDLPQSLFQNGLMDKIYKCSYLRKKYQMISHVIIHSIKEIINNNIIIRILEFGGGTASLSVEVIGEIVALLQENPNYQVEIEYTWSDISPAFIADAKNKINKIINDAAITNGLNVIYRSLTIDESLLENQAIKPSYYDFVIMSNVLHVVKNIKQAVEQMYQLLTPNGQLLFIEPPYKSVLIDSIIGSFEQWWSFTDTDIRKDRCGMSQQSWYQLLKTCNFKDILMSKECIFVGSVIHAQKPPISLLNSQPKHDNIIIYGGGGNLSFVENIKLDSNSKSLIQIETIQEFNQLLSQSTITNDSIIYFIKTLETLSLDNYKQITLEYIEINQRLLQINSLCKHVLIVSDSRKTNYLASSVVGAARYFDEFQQLKLHTLDFDYDSTQNYINSKNNKMVQFINILVDSKTNVHKEMIIINNKVYYEIVQKEKNLKLKYNSESFENQNNLMCSLSPNLEYQLQSKQIKLRDNQVEVKTIATGINYKDYLNFSGSNNNNGDDNTGLPQFGYEFSGIITRVGNNVKDYKVGDNVFGLSNSCTSSHIVTNFKNIQLKPSNISHNEASSIPIDYLTSFMSLFNVGSLNIEDNESILIHLGSDSFGLSTFEILKWKGFKSNLFVTVDLDETKQYLLDRYGDFITGIYSNTDKSYVTEIKNELIKLGSKKKGVDLILNTLPSDFMDSNFELLTKSGRIIDLTSNHLNQSEFLKNINFKYNHGYHNFQLSLIQKNKIQKCLYEISHAIENGELKTIPIKEFTNLNIKDAIKYITNGNIEKITVSHDHEIYSDIIYRSLDEKEFSILKSNYQINSNNLGKNILITGQSGIILEILKWIIKYSNINTIENVIILSRSSLKWELELLINQTKLSNNNIKFHFKSVDVGDSEQVDNAINEILNENQQITNIDSIYHFAFQQITCKVQEINMKHLDISHGAKSMGAVNLHNQSIKRNWKLINFVMASSALSLIGSTDQCTYACANLLLDSFSKYRESLGLPSACINLGSIESTGFVSKNESISEFTDGIGYVPTPINLVLGLLDLQIQNAGKFTNSMLSNLISSKFKNIQQTSLFLKFDYLMNLNDNSEQTKKENIGNKNIDELFIEKVSELFSTDQSRINKNLRLIDYGADSLIIVQLKNWIDKEIGINLITIKQLQNNTINISIKMILNSLMKNNQI", "length": 2514 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "B0G110-1", "protein_name": "Acyl-coenzyme A oxidase", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MYKNRIEIIKKHLEVNNSQTTNNKDEVLEKELFNSIDTNINVGELKLLIDSVEESKYKDETREFIRNHPKFKENFIGLDMATYRQLVLEQCAAIANRGLIHFTDIKNNLHRYIGALEMFALYNNNILTKLSVQYTLFGGPIIFLGTSRHEKYIEDANTLKTMGCFAMTEIGHGSNVRGIETTAHYDKQTKEFIIHSPTPTSEKFWIGCAYLHATYAVVFANLIIDGTNYGIHAFIVPLRCPKSGAIMKGITIKDCGHKLGLNGIDNGQIRFDQVRIPRENLLNKYSDVSEDGVYKSQFNTPIKNFAATMSPFIVGRMAITKGCSGAAKTSLSIAIEFSHIRKQFGPSSNKELPLITLSSQQRRLMAPLARTILFDLYIQRLTNELCQEKLPASIHAHCSGIKAVYSWFCVAALQTCREACGGQGYRSANRIAEFKNDCDIICTYEGDNTVLMQQLAKYLLGVKQKQTNTTTNRIYLDGEDAKSLFFNFSNINQLFETREEMRLAELKQIIDNSKESAYFAFNNAIPWAVKLGFAHMTKIVFQNSINTLKLKNVKPLTHLIMLDALVSIEEDLGWFVSNHLISPNVAQSIPFLIQDLCFEVTKVSKQIIASFDIPENCKPSSKDLISDLF", "length": 629 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "B0G138-1", "protein_name": "Probable polyketide synthase 21", "gene_name": "pks21", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKLENKEIAIVGIGFRIPQGKESINNGSVSHLWNNLKNGFSGIVETSERWSDNINLLGEVNNKFGGLLPLKEWSDFDPVHFAINPSEVPLMDPQTRLLLKCTWEALEDAFIDPIDIRGSNTSCFIGCSTLDYSTTNRDFNETSENYFASNVLHTISNRLSFSYDIRGPSMTIDTACSSSLNSIAMGFQSIQNGTSNLSIVGGVSLLLDPYISKSFSFLNMLSKKGKCKPFDSEADGYIRAESCGIVILKPLSDAIRDGNNIYCVINSFSSNVDGGGLNDKSNFYSPSKQSQSDNIKLALKSANMKASDISFVECHGTGTPTGDPIEVEGVSMALNSSKTSTPSKPLLIGSLKSNIGHSEAASGVASLIKCCLMFKNKHYAPNVNFDQPNPKINFKDWNIKVVTEAIPFTNNNEKPVSMVINNFGVTGSNCCLILSQFIEQSINQNGNGHSYPAESQQQQQQRFLIPFSANSVKSLKNYEDLIINDIKISTNSFKEFVKNQIYSKSKKLYQRSVLISSNWDQLKTKNKYFKTNNDKSSNITIKRNQPLVVIVFGGQGSQWNKMAQQLYECEPIFRSSMDKFNKELSKYYGYSVLDKLRSIKDDDIISIHQPIIAQPSILMLQISLFELYKHWGINVSFIVGHSLGEIATSYCSGMVDFQTVCKLIYHRSISQNNTNGCGKMLSVNISHSEFIELYSNKYPTIEVACYNSPTSIVIAGNENILKEISLNLKENNIFCAFLGSLSSFHTSSQHSTKNEILPLDIPSKQSRIPTFSTVTTNLFNHETTPFNSSYVYENIIQPVRFSQTISNLYQHIENNKLGNELIFIEVSPHPSLSFYLKQMIPKSSSYFNSVSVLTSTNKKNSNDLDEIHSTISQIYCLGYDVNFKCQFNHNDDDVSSIRNSKVNISLPNYQFDEQHYWKVDINFEQYRLNGPNVFNSLGKSMINYSSNNKSYESIIDINRNPFKYLKDHIVKGKYYFPGIGYADNIMKLYPNQDIIINNLEFLAPFVLKENVKHTLQTNVYQLGNTDYRVTFNIKDNKTNQWVQTCTGNFQLISLKDNNNDHSSKYDINQLLSECNFTTLSKQEVYKHSRSITGITHLGAFQGIEELYFGNDCIISKIQVNTENFDIDGKPVYQTYDKSFFNTALLDSCSQTIVGFITNSSQFVFERLEGLKVYSENIPTDKLKYKNIYCQAKFISLESDSYKSSVLVLLEDGTKLLEMDCISLHSTLPLLNSLLINNPTTELFTNNLQCKDSLVNILSIDNNQTFSSISSSNTVTEIIKQTIKPIINEKIVFRILQSFSDLELSKQIIETLNQIFDDNSLQEIDIEFTIIDNSNDKLPTLHDSSLIFKNDITQLKPSYYDIIINNNNDGDDETIIKSIFNILSSNGLLLIIGDDIGDKYNIDSLINLGFNENKIQKSNKVIQSQKSTILSNELTVVPNNKNDNIIIYCEKESKYTNEFMKLISNNHISCKQTIISNINEFNQLLPSITNDSIIYFIKSMEQLEMNNFKQITMEYIEINQQLLKHSLTCKHVLITIDSQIKNYLSSSIIGTARYFNEFPSLNLYSIDFDNQLSISSLLNKIINQLIENSNNHIQREYIIRNNSIYYEILKNEKNIKSNFNSNSFEDNDFMTLLDSTNLEYKLASKPKKLKKNQIEVKVLATGINYKDYLIYRGLVVIDENVSISKNPLGLEFSGIITRISNENQNCEFKVGDNVFGIACDTTASHVIADVLYVSHKPENISHVEAASLPVIFSTCLHGMFNIGNFNIDDDEVILIHSATGGIGLATLEILKWKGHKSPIFVTVGSKDKEQYLIDNYGSFITGIYSSRNKNYVNEIKSKLNQLYGTTGKFNGVDLIINTLPNEFTHSNFLCLKERGKIIDLSITHLNNNEFLNFNNFKFNKSYHNIELMHINKKVVSRLLKSISNALNENKLKPIPITTFQIEDVKEAIEYINQRKHIGKIVLDHSCSNGSIGSDGLLNQLIESDNNEKNHTILKYDFKIDTKNIIGKNIIITGQSGIILEILKWLIKYSPTESFENIIILSKSSLKWELELLINKTISRKDNNTKFHFKSVDVGDPIEMRKSINQILLENPNIDNIDSIFHYAFAQITKEVEEIDIESLDISHNAKTMGAINLHEISIEKSWKLKQFVMASSIASLFGSFNQCSYVSANLVLDSLSRYRKSIGLPSTCTNWGAIKSAGFVSRNELVSKMLDDQGFIPIPTNIILGSLDLQLQNSNKNSNLIVSKFNYDSIKKLSSETSTFQRLDFILNSIKEKDNDSNGGENSVSESIQTKILNKISELLSIEQSKINTDIRLSDYGADSLTSVQLKNFIDKDIKSNVITLQQLQNNTIDMNIQTILEQIKKLDSNETKGKSKNIIKKDSAPTLDYWRNEMKLDESIQAIKMNPIDFRNDSKVFLTGATGFLGVHLLSNLIKSPNCSVVYCLIRNKKSEPNPINAIINNLKHHKLYHFHNEFELSKIKVIVGNLASPLLGLSKLDFDYISNQINLIINSGADINLASNYEESKVVNIGGFIELIKLSTTGDYQKPIVGFSSVSVFFNASNCKEFDEETVIPTIENINNLPGGYMKSKVVVENLLREVAKRGIPSMLIRPPIIFSHEETGIGHDSDFFQLIIQSCYAVKKYPKIDKNILTSPIGWISLNTIKMIGNEKCWNKSSSNQLNIYSLNSEVSAMNPSFSFLEKQYGCEMVEYEQWKNIINQSKILSCVKLKTFHSLDDLYNIYNLGNGFGVSKKTKELLQSMNSYEGGMVNEKMIQNHINYIFKN", "length": 2779 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "B0G149-1", "protein_name": "Transmembrane protein 184F", "gene_name": "tmem184F", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MLSHINIIYIIWILLFFFTCLISFFLVNRHLVNYSSPNVQKNVVRIVMFLPLNSGLSILSSIFPGIAIFNSLVRNCYMAFTAHCFFSMMTNSIGEKNMLDLFESQGKMKFLCCKVMKLNRKLFNTLRFGSIQFFIVKIFCSIATITCISISEEVHSILNVQSFAPYEFLISLVASIFCTISLSIFLAISKEKLSQYWPMTKYRIMIFIFFIEQFEYLFFALIFLRGPFFLGFKNSFDQTIFILHFTVVVTMFLFSIVYLFIYSYKNYRNKASNEPLVGRNFKDSFGLLNYLDVLNPKDLFIDFASIFKTNNNKFKELVEENGDKKPKKNIEDQNQENSNDQPLSIQMA", "length": 348 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "B0G188-1", "protein_name": "GATA zinc finger domain-containing protein 16", "gene_name": "gtaP", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNSYQIQNQPYQQIQNTHPSFQQVQPMQVPHLQQQQQHQTMIAQQQHTPPQQHTPPQMNMIQQHTQPMLSQPQISLQMQPPSPILASQQQQQHMQSSPILASSNLTNSNNASQTTLPIITSKLLLKKEPIDQEVVNSTHKTTTTNNKPPKQSKRKEKERLEEEKQTVAQQQQYQPPFIPLASNESNSDNPFKGSHAYGVSTTPYGNSQFNNNNNNNNNNNNNNNNSNNNSNNNNGNNNINNNNNNSNNNNNNNSNNNNNNSNNNNGNNNNNNNNNNNNNNNNHNTNNNNSNSNNNNNNGYQQDKKDDYSMMIWSEVGRKINILIRTTSKATKGTPISTQEIAEAIGASNGVTADLVELIKSINDPTYVRKLPPSSISNTPTMGSQSGGMVYNSSPMLSPSTMSPILQHGNYQMGGDMYFGGNNQFSGDKQSALNNVKNSKGGNTNNSGGGSSSGGTNDTQAKKPARRRKMRYGGTELSCHTCGVTNTPEWRRGPNGAKTLCNACGLAWAKSVKSEKQKELLANSTGVNITEPKKAQKRKKESSDNNNNNNNSSDSNKVLKSDDGSNNTNLTNDDDNGYPSSPNSSNSTSPSSHNINNNNNNNNNNNNNNNNNNNNNNNNNNNNIGNNNNNNINNNNTTNSITTPTTTPFPTTIPAMQIVSQLPVMVPQTQQQPHMSGNIISFQALHQNSGYQHYK", "length": 695 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "B0R191-1", "protein_name": "C-X-C motif chemokine 11-6", "gene_name": "cxcl11.6", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MKTLAAFLLLSCLIAGEVNGQDRSSRARCFCVDKGLNMVLLKNLDKVEIFPPSPSCNKHEIVVTLKNGAGQKCLNPDSKFTKNVVLKAIGKRMQQSVPHSTTTGTVKSSMTSSTSAPTAFK", "length": 121 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "B1AV09-1", "protein_name": "Leucine zipper protein 4", "gene_name": "Luzp4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MANHEDEIRQLRYLEAANSEEEYNEENDIQSESSRGQAFFPGHPRGRGHRRDSRGRNGHFFRQRFSANHPLLHLTRQVNLESLTRRNGNQSEERQLQQERIQLFFRSLHGLSQSHDHHIGRSHGHYSRRSRNRFRRAPVHSERSHVYSGRTNNYTDRPHHDLSDRPHNQLSVRPHPDLSGRPLHDYSGRPHQNHAVRLQHGHSDRYHLTHTERVLPNNSGIDHPGHTERDNQVQRGRAHDNQSGLAHHNHDGRSHHDHSGRAYHGHARRAHNNQSWRSDNNQSWRDLNQSWRGQNNQSQRGHDNQSQRGHDNQSRRGHDNQSQRGHDNQSQRGHNDQSWRAHNIRSRRDRYHTSLRSSSIQSWMLHERERYHGPRGRNGPRDASPPGSEPEIDRSSAIRERTDYLWVQEHRRNETVELNVGLEDGYSSAEESDESLDRLTCRSMLDTLY", "length": 449 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "B1AY40-1", "protein_name": "SSX member B8", "gene_name": "Ssxb8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "METVSFCEKVPMEVLYEPKNICKAFQDISTYFSDEEWGKLTQWQKSAYVYMKRNYIRMTDLGVTVNQPVFMSGKEQDKQSLVEGIEVHDSEDECFEGSFGVTPIKQMKLTPVTISIHNVEGSLASGENNSNLAETSGIQVNVWSHRLRERKYRVIYEEISDPEEEEDDDY", "length": 170 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "B1AYI3-1", "protein_name": "Predicted gene 13272", "gene_name": "Gm13287", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLPVHLFLVGGVMLSCSPASSLDSGKSGSLHLERSETARFLAELRSVPGHQCLRDRTDFPCPWKEGTNITPMTLGETTSCYSQTLRQVLHLFDTEASRAAWHERALDQLLSSLWRELQVLKRPREQGQSCPLPFALAIRTYFRGFFRYLKAKAHSACSWEIVRVQLQVDLPAFPLSARRGPR", "length": 182 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "B1AZM5-1", "protein_name": "Predicted gene 12886", "gene_name": "Gm12886", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVLPCSLWLLSVCLLSWCCDAKLPVALDPESESVPKPPVLKTATEIAAIVVFMKTSNETPKSGTYGQSLQDGKNKIKDVEKEVLDACSQLCQSLAQDPNLHHGYILRAYFKEHQFLCCF", "length": 119 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "B1B0R2-1", "protein_name": "Spindlin family, member 2D", "gene_name": "Spin2d", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MESSKLTKKRAGRKRQRSRSPALPKRNIVGCRISHKWKEGDEHITQWNGTVLDQVPVNPSLYLVKYDGIDSVHALELYKDKRVLSLKVISKRVVSSGVTDSSFADAIVGKEVNHLFEGEHGSKEEWRGMVLSQAPILDNSFYITYERDPILYTYQLLDDFKEGDLQIMEGFSDPPSLDIDLELVDGLIGKHVEYTNDDGSKRDGLIIYQIETKPRVYLVKYEDDVHIHVTHLEKEL", "length": 236 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "B4F7F0-1", "protein_name": "Claudin", "gene_name": "Cldn6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASTGLQILGIVLTLLGWVNALVSCALPMWKVTAFIGNSIVVAQMVWEGLWMSCVVQSTGQMQCKVYDSLLALPQDLQAARALCVITLLIVLLGLLLYLAGAKCTTCVEDKNSKSRLVLISGVIFVISGVLTLIPICWTAHAIIQDFYNPLVADAQKRELGASLYLGWAASGLLLIGGGLLCCACSSGGTQGPSHYVARYSSPVPHSRGPSEYPSKNYV", "length": 219 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "B7ZW38-1", "protein_name": "Heterogeneous nuclear ribonucleoprotein C-like 3", "gene_name": "HNRNPCL3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MASNVTNKMDPHSMNSRVFIGNLNTLVVKKSDVEAIFSKYGKIAGCSVHKGFAFVQYDKEKNARAAVAGEDGRMIASQVVDINLAAEPKVNRGNAGVKRSAAEMYGSSFDLDYNLQRDYYGGMYSFPARVPPPPPIALAVVPSKRQRISGNTSRRGKSGFNSKSGKRGSSKSGKLKGDDLQAIKQELTQIKQKVDSLLENLEKIEKEHCKQGVEVKNAKSEEEQTSSSSKKDKTHVKMESEGGADDSVEEGDLLCDDDNEDQGDNQLELIKDDEKGAEEGEDDRDRANGQDDS", "length": 293 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "B8JKF6-1", "protein_name": "BTB domain containing 35, family member 13", "gene_name": "Btbd35f13", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRFLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGKTWCLHKVFLCQSGYFANILKGTWRESHHGAINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYVLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "C0HKD1-1", "protein_name": "Spermatogenesis-associated protein 31F1B", "gene_name": "Spata31f1b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSTMCFLWDTECPLYVYFCFFIIVLIVWQVRQNYQGLKCENRRSCCRRHQKVRQRAKDAASRARRLSREEDEKPCELLSIMKSQSWVPKQGNVRQLLCLDPSCQICEATTLEIRQLLQSKKSQISPALLGLPQRAACLEMPISSESFEWNQDFYSRYSTNSPVVPGNQTLTQLTEELTESTNADGVLLCWTDPLQIGQEFHLADMPMASETLVSPGLEEPVVLMNEEDTVHSNLNYIQQLQDHEALNSQIPFQTLTPQLTVTHPMAVSIVTDAPQPFLSPEVLRLLEIHVKKLMHFQRWGLPRRVEESLKQFMPNPPVYLPPEHNQPVSFILNTSSQDCVHRFEGISPETWYSYMDGQPIQTFWVSEWSSGDQGQRLSCKPIPSPVEKPLLTPDYELLHDLCLSPEGQVDGSQSNLQKKFTQLFCGLPSMHSESLGSTFLCTQGVSKNTLKPPYKEPHFLKVSPPIPLPEAAPPPSSTSPNESLDEPQRAQIGGVPFLTLSECKTLEWHLLQRQLQLQWGLPAVIARPPRVQSHTQYKHKPWNKAKPRETLKFFGPGKPFSALTRELFFIPQHARRLLEFHLQKRLIHLRWGLPQRIQRSINMLLSSTDLQSLPCGGSRLPNVSISQPGKPEAYGSGDTFLPTAGKGTTPMPHLFAKAQEMLKSHDTKCEQIREGKVPACVQSAWKGRIPGDLAAGTLFPNIPQGQPLELQAENNPDLHQEAVSWKPMDLDQEAQAFSGVFIEHCRRPQALSEETIKKLETTLRHKYLAFLSGLQALYCMAPTKATSPTVDQSVITTMPWSVKSPQKPLSQKSPLEALCLSGLEPCTQDDKETSANIAEEFQHGAQGHGRTEKVPPERQPLLNRPYSLDTEIMERVSFYLKRKALDIKLGISLKESVFQEPTATDLESESVQEPLGSPRESTLLQGPPTLCHVPVAPDPDKVCLKQPATAVQVVFQEQNQPSSRAVPHRSARQGSQVHRNMMEAQVHYVQMGTGGEMLNLGEPFSTESQSPGKSKSGYVPTVAGKRKIPGKPKVVGDLGEGDAGLGFSLVSLKTRQDGEQEKRLLHRQLQGSSLQAQTFHLEGACPHSPQESPELQFADPPPEVFMETDSEQDMEDSQSKESIVPEPARTAKAPQPMLSRASQGLPFPRSPTQRKPSQGQPGPGHVPPGHATPASPYTRPSRLPEAGLKNKMKLFFHSIKLKMKSKAHTEPSTVSTPGKVAKTSKENIDRGLPQAKSPTKKTKPEDFRGPKAQFSVVGPCLTPSYILDSKFWPRPRRVGSVSVLGHSYHCPRHCPRLAYANQQRNPP", "length": 1308 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "C0HKD2-1", "protein_name": "Spermatogenesis-associated protein 31F1C", "gene_name": "Spata31f1c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSTMCFLWDTECPLYVYFCFFIIVLIVWQVRQNYQGLKCENRRSCCRRHQKVRQRAKDAASRARRLSREEDEKPCELLSIMKSQSWVPKQGNVRQLLCLDPSCQICEATTLEIRQLLQSKKSQISPALLGLPQRAACLEMPISSESFEWNQDFYSRYSTNSPVVPGNQTLTQLTEELTESTNADGVLLCWTDPLQIGQEFHLADMPMASETLVSPGLEEPVVLMNEEDTVHSNLNYIQQLQDHEALNSQIPFQTLTPQLTVTHPMAVSIVTDAPQPFLSPEVLRLLEIHVKKLMHFQRWGLPRRVEESLKQFMPNPPVYLPPEHNQPVSFILNTSSQDCVHRFEGISPETWYSYMDGQPIQTFWVSEWSSGDQGQRLSCKPIPSPVEKPLLTPDYELLHDLCLSPEGQVDGSQSNLQKKFTQLFCGLPSMHSESLGSTFLCTQGVSKNTLKPPYKEPHFLKVSPPIPLPEAAPPPSSTSPNESLDEPQRAQIGGVPFLTLSECKTLEWHLLQRQLQLQWGLPAVIARPPRVQSHTQYKHKPWNKAKPRETLKFFGPGKPFSALTRELFFIPQHARRLLEFHLQKRLIHLRWGLPQRIQRSINMLLSSTDLQSLPCGGSRLPNVSISQPGKPEAYGSGDTFLPTAGKGTTPMPHLFAKAQEMLKSHDTKCEQIREGKVPACVQSAWKGRIPGDLAAGTLFPNIPQGQPLELQAENNPDLHQEAVSWKPMDLDQEAQAFSGVFIEHCRRPQALSEETIKKLETTLRHKYLAFLSGLQALYCMAPTKATSPTVDQSVITTMPWSVKSPQKPLSQKSPLEALCLSGLEPCTQDDKETSANIAEEFQHGAQGHGRTEKVPPERQPLLNRPYSLDTEIMERVSFYLKRKALDIKLGISLKESVFQEPTATDLESESVQEPLGSPRESTLLQGPPTLCHVPVAPDPDKVCLKQPATAVQVVFQEQNQPSSRAVPHRSARQGSQVHRNMMEAQVHYVQMGTGGEMLNLGEPFSTESQSPGKSKSGYVPTVAGKRKIPGKPKVVGDLGEGDAGLGFSLVSLKTRQDGEQEKRLLHRQLQGSSLQAQTFHLEGACPHSPQESPELQFADPPPEVFMETDSEQDMEDSQSKESIVPEPARTAKAPQPMLSRASQGLPFPRSPTQRKPSQGQPGPGHVPPGHATPASPYTRPSRLPEAGLKNKMKLFFHSIKLKMKSKAHTEPSTVSTPGKVAKTSKENIDRGLPQAKSPTKKTKPEDFRGPKAQFSVVGPCLTPSYILDSKFWPRPRRVGSVSVLGHSYHCPRHCPRLAYANQQRNPP", "length": 1308 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "C0HKD3-1", "protein_name": "Spermatogenesis-associated protein 31F1D", "gene_name": "Spata31f1d", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSTMCFLWDTECPLYVYFCFFIIVLIVWQVRQNYQGLKCENRRSCCRRHQKVRQRAKDAASRARRLSREEDEKPCELLSIMKSQSWVPKQGNVRQLLCLDPSCQICEATTLEIRQLLQSKKSQISPALLGLPQRAACLEMPISSESFEWNQDFYSRYSTNSPVVPGNQTLTQLTEELTESTNADGVLLCWTDPLQIGQEFHLADMPMASETLVSPGLEEPVVLMNEEDTVHSNLNYIQQLQDHEALNSQIPFQTLTPQLTVTHPMAVSIVTDAPQPFLSPEVLRLLEIHVKKLMHFQRWGLPRRVEESLKQFMPNPPVYLPPEHNQPVSFILNTSSQDCVHRFEGISPETWYSYMDGQPIQTFWVSEWSSGDQGQRLSCKPIPSPVEKPLLTPDYELLHDLCLSPEGQVDGSQSNLQKKFTQLFCGLPSMHSESLGSTFLCTQGVSKNTLKPPYKEPHFLKVSPPIPLPEAAPPPSSTSPNESLDEPQRAQIGGVPFLTLSECKTLEWHLLQRQLQLQWGLPAVIARPPRVQSHTQYKHKPWNKAKPRETLKFFGPGKPFSALTRELFFIPQHARRLLEFHLQKRLIHLRWGLPQRIQRSINMLLSSTDLQSLPCGGSRLPNVSISQPGKPEAYGSGDTFLPTAGKGTTPMPHLFAKAQEMLKSHDTKCEQIREGKVPACVQSAWKGRIPGDLAAGTLFPNIPQGQPLELQAENNPDLHQEAVSWKPMDLDQEAQAFSGVFIEHCRRPQALSEETIKKLETTLRHKYLAFLSGLQALYCMAPTKATSPTVDQSVITTMPWSVKSPQKPLSQKSPLEALCLSGLEPCTQDDKETSANIAEEFQHGAQGHGRTEKVPPERQPLLNRPYSLDTEIMERVSFYLKRKALDIKLGISLKESVFQEPTATDLESESVQEPLGSPRESTLLQGPPTLCHVPVAPDPDKVCLKQPATAVQVVFQEQNQPSSRAVPHRSARQGSQVHRNMMEAQVHYVQMGTGGEMLNLGEPFSTESQSPGKSKSGYVPTVAGKRKIPGKPKVVGDLGEGDAGLGFSLVSLKTRQDGEQEKRLLHRQLQGSSLQAQTFHLEGACPHSPQESPELQFADPPPEVFMETDSEQDMEDSQSKESIVPEPARTAKAPQPMLSRASQGLPFPRSPTQRKPSQGQPGPGHVPPGHATPASPYTRPSRLPEAGLKNKMKLFFHSIKLKMKSKAHTEPSTVSTPGKVAKTSKENIDRGLPQAKSPTKKTKPEDFRGPKAQFSVVGPCLTPSYILDSKFWPRPRRVGSVSVLGHSYHCPRHCPRLAYANQQRNPP", "length": 1308 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "C0HLM6-1", "protein_name": "Small integral membrane protein 20", "gene_name": "Smim20", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAAARNLRTALIFGGFISMVGAAFYPIYFRPLLRLEEYQKEQAVNRAGIVQEDVQPPGLKVWSDPFGRK", "length": 69 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "C7G009-1", "protein_name": "Thioredoxin fold domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNLILNGNWLVKFGAGWSGHCKKLQPVLENLAQHYNSDNENSKVKVAQVHCEEYESICIKYNIIGYPSLVFFDEGEIKHYRGPRLFENFKEAIDKHLNKEFVAFSQNQPSKIIVITNENLDLLLTGNWLVKFGAAWSLHCKKLQPVLENLAQHYNSDNENSKVKVAQVHCEEDNSICKKYNITGYPSLVFFNEGQIKHYTGPRQFENFKEAIDKHFKYGVKWSGHCKKFQPVLENLAQHYNSDIENSKIKVAQVHCEGDDSICKKYNITGYPSLVFFDEGETKPYRGLREFDKIKEATDKHFK", "length": 303 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "C7G010-1", "protein_name": "Calcineurin-like phosphoesterase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKLKIKFSIISLFILKLVISKPILKFNNNNQFKIIQFTDLHYGSEPVDDIDTIFSQVNILDYEKPDLVILSGDMVTGYEEQFEDDDRNYWKYWNVFTRPFVERNIPWAITFGNHDGEGALSTNEILKIDQTFNLSLSQSNPVEMHGIANYVLKISSSNSLKSEPASLVYIFDSSTKGCSKLDWGCVHQDQVDWFKNTSKSFNKTDSIAFVHIPPVEIIDLWNNYPVYGNYSETSCCFDNDYGDFVSSLVESGDVHGLYFGHDHENDFHGDYKGVDLGYGRKSGAGSYSSKKPLGARVFQLTESPFTLSTWIREEDGNIVSQVIHPPSEFDRKPLQCKMKDKYSKKELIAIKVIGGFLIFLGIVVVGLIGFFGFKHYKKFKKQTLEMQNLV", "length": 390 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "C7G064-1", "protein_name": "SET domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKKDEKQFQQFPNKGRTVQANTDLPKGSTVFRCAPFASSIEDSDKLATEKYCGFCLQRIPKSDSKECLCKNCKLYSVCKSCRSINESAVEPFQIIIKSTFHLGSDTRDMRLLLRIIANIANGKQGMQTPIDDYQDFMGLTSTLDKVDKEHMTKFKRGVTSISSLISSVRGVGYLKNTITIHEILECFSSVLTNAHQFSYATSKEIGRGVCPTGYFNHSCMPNTTWSLDDQGMLLFSTSSNVKKGDELSLGYLANEYPLKNRRRELLDGYYFFCQCPLCEFQSNLSGYLCEKCKEPLLNDSIVYHEPSLTNPLDTGIGLIKHLRKMIDFRQQSVEFKKMFSSEQLSNILQKGVPKHIQSVFNCDASDNEELQQIVEISERSIKSLPLINGEPIDFYPLSDRNYYEYFKQLKNSKISSPEELQRIKDKILSLINPTIYNSFKDKIDKRLLI", "length": 449 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "C9JPN9-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 12", "gene_name": "USP17L12", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEEDSLYLGGEWQFNHFSKLTSSRPDAAFAEIQRTSLPEKSPLSCETRVDLCDDLAPVARQLAPREKLPLSNRRPAAVGAGLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCHRHKGCMLCTMQAHITRALHNPGHVIQPSQALAAGFHRGKQEDAHEFLMFTVDAMKKACLPGHKQVDHHSKDTTLIHQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVQQALEQLVKPEELNGENAYHCGVCLQRAPASKMLTLLTSAKVLILVLKRFSDVTGNKIAKNVQYPECLDMQPYMSQPNTGPLVYVLYAVLVHAGWSCHNGHYFSYVKAQEGQWYKMDDAEVTASSITSVLSQQAYVLFYIQKSEWERHSESVSRGREPRALGAEDTDRRATQGELKRDHPCLQAPELDEHLVERATQESTLDHWKFLQEQNKTKPEFNVRKVEGTLPPDVLVIHQSKYKCGMKNHHPEQQSSLLKLSSTTPTHQESMNTGTLASLRGRARRSKGKNKHSKRALLVCQ", "length": 530 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "D3YTW8-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r258", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSVRGKSLKTTEEVALQIILLCQFGVGTMANVFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTVFPNNMMAFAPRNPPTELKCKLKFFSHLVTRSTNLCSTCVLSIHQFVILVPISRGKLLLRASVPNLVSYSCYGCWFFSVLSNIHIPIKVTGPQITDNNTDSKSKFFCSTSGFTVRIVFLQFSHDATFMSIMVWTSVSMVLLLHRHRQQMQHILTPNQDARGQAESRATQTILIVVVTFVSFYLLNFICIIFHTFFIHYNLFIRLLGEILAAGFPTISPLLLIFRDPKNPCLELFHCFKPESLQNL", "length": 314 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3YTX5-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r259", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSDHGKSVKTTEEVALQLLLLCQFGVGTLANVFLFVHNFSPVLTGSKQRPRQVILSHMAMANALTLFLTIFPNNMIAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIHQFVTLVLVNRGKLILRASVPNFVSYSCYSCWFFSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGIVFLQFAYDATFMSIMVWTSVSMILLLHRHRQRMQHILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNFICIIFHTLLMHSHLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFNC", "length": 305 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3YTY1-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r107", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQILLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMSAFAPKTPPNELKCKLDFFSHMVARSKNLCSTCVLSIHQFVTLVPVNRGKGKLILRASVPNLWNYSCYSCWFYSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGMVFLQFSHDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQDARGQAETRATHTILMLVVTFVSFYLLNCICIIFHAFSIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 307 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3YTY2-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r138", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSVHDKSVKTTEEVALQLLLLCQFGVGTVANVFLFVHNFSPVLTGYKQRPRQVILSHMAVANALTLFLTIFPNNMMAFAPKTPPNELKCKLESFSRLVARSTNLCSTCVLSIHQFVTLFPLSRGKGKLILRASVQNLASYSCYSCWFFSVLSNIHIPIRVTGPQITDNNTDSKSNLFCSTSGFIVGIVLQFAHDATFMSIMIWTSVSMILLLHRHCQRMQDILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNCICIIFHAFFIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 306 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3YXI8-1", "protein_name": "Predicted gene 10377", "gene_name": "Gm10376", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGSQAGSFRKASPQTPNIDENEKRIKRLEKLKRDLQNIKNERDILQGILAKYKDLNDRTNFETFMLEMQNNQMMTDLKRMSQDISEALYKCQHLTKENQLYCCRNCHLLIESNLIQHKVRMLWKENRQLLRKQIALEECNIKTKILCKEGSQKIKDEYSRQAAGKQIIVVPGSKEEAVMSNPCA", "length": 184 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3YYI9-1", "protein_name": "Predicted gene 7347", "gene_name": "Gm7347", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRVNVDGRETREGRKDADLPSERNEGRRRWTWRMCMAHRQTTSPVPVKSKKQFEKEEKELIKKIQLTTKETNELRDRLIYVTEGSMNKRPYHRQTRHYKELKLKEKEIMTFLHDLEMKNMEARENNQELKKEKNFYRNLHTRILLGENLIKKKLAILQQESKEIHADWAIIQQRLVELNLSGKDEQEKTSNLEAQENQVSEAARELGLATAEEDSILQNELPCQEAPAEHHPQHPSSSSDESSSDESSYSTCPEWE", "length": 267 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3YYY1-1", "protein_name": "Secretoglobin, family 2B, member 7", "gene_name": "Scgb2b7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKGTLLLLGLLVTGELSFQTTEACFPFFEAYASVLSGSRVWLYQELQAFDATAEEKVALEKIQDCYSEESIRNILLEPKIMEAMVASPECLSYYGLDNIRSILDYISKLLGE", "length": 112 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3Z236-1", "protein_name": "Predicted gene 3676", "gene_name": "Gm3676", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGSQTVSFRKASPQTPNIDENEKRIKRLEKLKRDLQNIKNERDILQGILAKYKDLNDRTNFETFMLEMQHNQMMTDLKRMSQDISEALYKCQHLTKENQLYCCRNCHLLIESNLIQHKVRMLWKENRQLLRKQIALEECNIKTKTLCKEGSQKIKDEYSRQAAGKQIIVVPGSKEEAAMSNPCA", "length": 184 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3Z8D1-1", "protein_name": "SIGLEC family like 1", "gene_name": "Siglecl1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLWGLRSLLLLHLGFLSPVLVDTKKTAVEDGLCSTVPCVIEFSKAPLRKPMIVSYRLNENISFHAGTSQPRGPVADLSTEEVEYCILLTHNMLGRKNMTYSLYVGLGAQKDLTQKQELHIPGSSMAGEPVSLTCTIHSTCQESKALFLSWKGPIMSSSTTVPINPSSALAIDPKPEDQDTTLRCHLKLSLDNLSSSKVVKLQLVSPARLLNYSCLLKRTLTCSCSFHGIPTPSVQWWVGRTPVSVNSIDAILHMTSTTLESWTNSTIHLMWEPEIIKSLRCEGKNQYGVHASGIFLIPDKSSVSSVFLRGLIQGIVYGAIASALFFFFLVVLGMKILNWWEENQTCKNEEAPTLKKPVWGGAKPAEVGS", "length": 369 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3Z8T0-1", "protein_name": "High mobility group nucleosomal binding domain 2, pseudo 3", "gene_name": "AABR07053402.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPKRKAERDAQGDEAKAKDEPQRRSARLSAKPAPSKPKKAPAKKREKIPKRKERKADAGKDANNPAENRDAKTGQAQKAEGAGVAK", "length": 86 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3Z9U8-1", "protein_name": "S100 calcium binding protein A7 like 2", "gene_name": "S100a7l2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAQNLTSSEQEVMKLFDLFQNYHVRRTDKLDVQETKRVLREFFPNFMKALNASGIKILNDLEKEITLDEIWDMIGRMAMAYNKKNSNALKD", "length": 91 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZAM9-1", "protein_name": "Olfactory receptor", "gene_name": "Or4f60b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKKVNYSVTSEFVFLGFTNSWDIQLLLFLVSSMFYVACIMGNCLIIFTVASDTHLHSPMYFLLANLSFIDVGISSATSPKMISDLLKKHKVISFRGCVIQIFFNQAIGGAEMVLLIAMAFDRYVAICKPLHYLTMMSPQMCLFFLITAWVVGLMHSVIQLIFIVNLPLCGPNILDSFFCDLPQFIKLACMNTYRLELLVSISSGFMSLVSFFLLSISYIVIILTVLKHSSSGAYKALSTLSAHVTVVVLFFGPAIFFYIWPSSTHLDKFLVLFDAVVTPFLNPVIYTLRNKEMKRAMRRVFRHLMGYRQIS", "length": 311 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZC26-1", "protein_name": "Ferritin", "gene_name": "Fthl17fl", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAEASSQVRQNYDRCCEDAINNHIRLLLQASYSYLSMAFYFDRDDVALGNFKRFFLSKSHNCKASAEMFVFMQNKRGGHVFLPSIAKPDRESWHGGLRAMECAFRMEMTINQSLLNMHELAKGKDDAHLCDFLGQHCLDQQVHVLKKMGGYLTNLRQMGAPEQGLAEYLFDKLSLS", "length": 176 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZCM9-1", "protein_name": "Dynein axonemal assembly factor 3", "gene_name": "Dnaaf3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTTPAGSGNGFGTVSWWGLSPALDLQAESPPVDPDSQSKTEHKIPELDALLLGSVDGRHMLRTLARAMLWPLRRFNFYVLENNLEAVARHMLIFSLALEEPEKMGLQERSETFLELWGNALLRPSVAAFLRAQASHLSNLVPEPDRLEELLPWLSLRPLKFRERDALEAVFRFWSGGEKGPEVFPMSRLWDSRLRHYLGSRYDARRGVADWDLRMKLHDRGAQVIHFHEFRRWRDTGVAFELRDLSAYHVPNRTMASGRLLSHRGERVAARGYWGDIATGPFVAFGIEADDKSLLRTSNGQPVKTASEITQHNVTELFRDVAAWRGPRAIKGNVEETKSPEPDAPAQEPFTIHFLPLDSSQTLHHKTCYRGRFQLLYVSCGMIHLLSPELGACVAPGGNLVVELARYLVDLRPKELKAFSDRVVEIAQAAGFAPHTGTKPSETFARFYKLGDSTRGGGDSAVESGPVPSKVLAPTPESINPPQADQAPSLEVMSPPKVDQTPPLEAMSPPEADQAPPLEAMSPPRADQIPPLEAMSPLQAEVVLPLEAISPPQADLAPPPEVISPVQEALAMSSAIAPLKHVT", "length": 583 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZCW3-1", "protein_name": "SPATA31 subfamily E, member 1", "gene_name": "Spata31e1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "METFLLLMNSISDFWMSSSSMSTVMDMIFAILCGVGFFFLLIPFLKEYPGSPPPGSKKNISEVVKRRQSKDRKKSVTVDGCRDSQKNSLDIQHDLQTMESPIQHLLLDSSPHPFWNSKEKLNQLSLPQLFSYLKVLEALIQQKFNQLLLGLSSVLSESVVATAWVSREPSSGERKTVRFSDSLGFDQALPLAKGPPQRCLDQPLPHQLVTPSLVGMTEIQEQENLPNSISYQTPSIFQSRARGTAYPTTATGIQVPLPTTNEPCHPGLNWKDIPSCKVQNCQGASSQPTESLARCTLPTKNTRSASIPPEHYLMVHHHEQPQHEEKAINLGEQQRTHARFLPSKEPAQLQGDSPPNSNGYGKNWPELNQPAQPSTLNSKTYKWNQMMGPVPTGMLLKKVIAKYGIPNTIKKDLKLRVKDLLCTSSSTPGESLETKNLTLRTDEHSMNTTENLSFLDPKTTMMKSNIMQLPMKHRQLPCDSKAEPYTKAAFILENLHHQDPGGIRVETASSARLRSPLFEQSPPEVQKTQSSPPPIDSHGHSRSHPDQWQRYQSVQPHALCSQAQPQQSRSIQGTGRSILQPNISVWMSKHERWMRSEDVASGHTSWSSRTVGYRDRVSPSVAKQTNILKIKEESPHVWRANLGSGEITNEQALNNSNEDFEPIEAKRSQGHLQMPTQQNTGYLHLKTEEYSNNDLKVNKQPQAWSVSHHADGSNTVHHAMVKLPSQHSLPSLQNGWQDPKTSQGLGDLLMNRDQSVETQFRVHKDKTEATNDSVFHPSEKRPSNLKYGGISQGERLGRVKSSISSFTQLKDSAKTESKSSPNIGGKREAPSKSSLKFIWNGAQYENLSTKLKGQRDSLKKDIPPPVTEQTQEVVHRINVIYSTAVELQSLMDSLVHKLVKTVGEPSELTRKHMTKVQEYKMESLPFQLGSSSQPSKGLHDPNKSRSVRRMSDDHTSPKEPNNHTFTYRGNRDKMQAGVDVQRVCYQHLDKVKIGFGQHSTPMRNGNPCFHKKAGDKQESSLADQSTGDADQTKPKNEIVGSPHRIPERHNQSSRYREIRDNQEPSVDHKAIDPHQNTKKGMGYSQLMSPKENHPVKISGTAAQGASDPEEIRTKSGKECSPHRSPKMHDHSLRHREVRDKPQPGINTQRAYDQHLNSPKKRMTSENLLTPKGTNHPCWHRVTGDKQQSSLSDQRACDPEQMRRSGMSSYPQRSPKVYHLSCSSEKIGEKLLPLVNDQRTHDKHPNSVKTRGCDNLPTPKGSNHPQGYRVIEDKQQLGLAYRRTCDPGQIKKSGMGKGPCKDTEECNLLYRYKIIGNKQQPGIVHRACDRHQSSKEGMGQGQPMNPKVCHSAKHRRTGGQDQSGVAAQGASNPR", "length": 1373 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZDD6-1", "protein_name": "Synaptonemal complex central element protein 3", "gene_name": "Syce3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MADSDPGERSYDNMLKMLSDLNKDLERLLEEMEKISVQATWMAYDMVVMRTNPTLAESMRRLEDAFLNCKEEMEKNWQELLTETKRKQ", "length": 88 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZDJ1-1", "protein_name": "Olfactory receptor", "gene_name": "Or13c3f", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDDMDKNNQTFVSEFLLLGLSGYPKTEILYFVIVLVMYLVILTGNGVLIIASIFDSHLHTPMYFFLGNLSFLDICYTTSSVPSTLVSLISKKRNISFSGCTVQMFVGFAMGSTECLLLGMMAFDRYVAICNPLRYSVIMSKEVYVSMASASWFSGGINSVVQTSLAMRLPFCGNNVINHFTCEVLAVLKLACADISLNIVTMVISNMAFLVLPLLLIFFSYVFILYTILRMNSASGRRKAFSTCSAHLTVVVIFYGTIFSMYAKPKSQDLTGKDKFQTSDKIISLFYGVVTPMLNPIIYSLRNKDVKAAVKYILKQKYIP", "length": 320 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZDT4-1", "protein_name": "Transmembrane protein 92-like", "gene_name": "LOC100364194", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQEAWVLDALTVIFGLLFSLQGVSSNKTIYKCEDIHCPKGFRCCDNECCLERKIWNTDNEPFRILFIILLVMLPLLCICGLVRRFCPKCRELQHEVRTADHQSPPDPPSIAPLESIWVTSLDPPPPYSQVVQKSTPTEPPPPYSLRPEDSTCPMRETSHETL", "length": 162 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZFJ9-1", "protein_name": "Family with sequence similarity 24 member B", "gene_name": "Fam24b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFSSFDLRTIIMIVIGSGILAAMFLLTGVVLCLYSKIARALNPSGTGKELDDQLCSDPCKTTQDQIIRVNSLNADTCRPFHGSTIGLENCQPLQCFSACGTYEGANSLTPCLCNTKEGL", "length": 119 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZFW5-1", "protein_name": "Transmembrane protein 107", "gene_name": "Tmem107", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGRISGLVPSRFLTLLAHLVIVITLFWSRESNIQACLPLKFTPEEYEKQDNQLVAALCLTLGLFAVELAGFLSGVSMFNSTQSLLSIAAHCSASVALSFFIFERWECTTYWYIFAFCSAFPAVTETALFIAVFGLKKKPF", "length": 140 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZG05-1", "protein_name": "40S ribosomal protein S12", "gene_name": "LOC120100003", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAEEGIAAGGVMDINTALQEVPKTALIHDGLARGICEAAKALDKRQGHLCVLASNYDEPMYVKLVAALCAEHQINLIKVDDNKKLGEWVGLCKIDREGKPRKVVGCSCVVVKDYGKESQAKDVIEEYFEYKK", "length": 132 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZGM7-1", "protein_name": "Peptidase inhibitor 16", "gene_name": "Pi16", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRNCRVSWMPQHSSAAVSGICPPQEGPWSSYSLWPEPPLLREKEAVAKDSRGVDSTLVQTQGTQPSWRHCVSWAGPPDTAPAAPPQPGWCLCGKDFKSSRQTPDRERQRGLATMHSSCSPWVMLPQLPLLLLLLLLLLTATGPATALTEDEKQTMVELHNHYRAQVSPPASDMLQMRWDDELAAFAKAYAQKCVWGHNKERGRRGENLFAITDEGMDVPLAVGNWHEEHEYYNLSTATCDPGQMCGHYTQVVWSKTERIGCGSHFCETLQGVEEANIHLLVCNYEPPGNVKGRKPYQEGTPCSQCPLGYSCVNSLCEPERKPEKAQDSPPRVTEVPGSRETGIPSLATSESLHFSSVTKVSDSLATEPSPAVETKAPPSLATEGPSSMATEAQSFLTEVPSVSATHIQPSLDEGPVNFLTSTHIPVPKSTDKEASSKSRAASVSPEKSLYPKMSPTETGESPPQIQEEAEPKAELPEREDELPEAEVELPEAEAELPEAKAELPVSSEALVPVLPAQERGGPKASLEHSSYPVPTYLPNFPSASGNATGGRTLALQSSRTGAEDPEKASWDSKNSAPVWGPFPGLLLPLLLLAGIF", "length": 596 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZGX2-1", "protein_name": "C-type lectin domain family 2, member M", "gene_name": "Clec2m", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQTESSLRLSQSSHHRLTFDLKKVVTLWILVIGVIAVLLWGFFSFPKKFTVTRQTKNEVCSDGVKICLHGWNKLNRNCFTHFSHANSWFTAKETCKFHDATLAVFNDQTELDIVMKQMEDIQTFWIGLYKKDFRGPWVWTNGSKYNNWYEVQDYGHCAFLHKSGIDSTNCNDLKEYICTQEGHCP", "length": 185 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZIZ8-1", "protein_name": "Ferritin", "gene_name": "RGD1560203", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAEASSQVRQNYDRCCEEAVNTHIRLLLQASYSYLSMAFYFDRDDVALENFKRFFLSKSHDCKASVEMFVFMQNKRGGHVFLPSIAKPDRKSWQGGFRAMECAFRMEMTINQSLLNLHELAKGKGDAHLCNFLGQHCLDQQVHVLKKIGGYLTNLRQMGAPEQALAEYLFDKLSLS", "length": 176 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZKK4-1", "protein_name": "Zinc finger protein 869", "gene_name": "Zfp869", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDTPIVGLSSPDQGLVSFEDLVVHFTQDEWDLLEASQKSLYGDVMLETFRNLTAVGYEWEDEAIEDHCEEPEVNLRDIVSHSEYTHEYEHKEYEEKPPDANFLTSVEGCVETKTSSGPSVCEVCLKTFGLYHLTYNGHHNYDYKELRGSQTEENDCEGNSCDKTSGSLQKEDKIHTGKKLYVCQECGKAFRYPSALQLHERIHTGEKPYECKDCGKAFRGLSALHLHERIHTGEKPYECKQCGRAFTYLSALQLHERIHTEERPCECKQCGKTFRYSRALKLHERIHTGEKPYECKQCGKFFRSHRTLKLHKRIHTGEKPYECKECGKAFRWLTSLKLHEKIHTGEKPYECQECGKAFRCQASYHRHKITHGGETLYECKECGKSFIYPSLLQVHERTHTGEKPFECKLCGKAFRCQSSLRLHERTHTGEKPYECKHCGKAFSSYNYLRFHERSHTGEKPYECKECGKTFTHRSYLRSHERRHTGEKPYQCIQCGRSFSRHSSFKRHQSVHGESPYEQYLIPLSPFSSKE", "length": 530 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZKM3-1", "protein_name": "Protein GPR15LG", "gene_name": "Gpr15lg", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRLLTLSGLFFMLFLCLCVLSSEGRKRPAKFPKLRPCCHLSPRSKPITWKGNHTRPCRPCRKLESNSWVVPGALPQI", "length": 77 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZL22-1", "protein_name": "Olfactory receptor", "gene_name": "Or1x2b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSKWGENETGVIEFLLLGITNDPQQQRILFWAFLCMYLVTVAGNTLIFLAISSDPHLHTPMYFFLANLSFDDVCFTTNIIPRLLAGHVSGTETISYAYCLTQMYFLISFGNVDTFLLAAMALDRFVAICYPLQYHTIITPRLCVGLASVVWISSGLIALVHTLLMSRLTFCSSIPEISHFYCDAYLLMKLACSDTRINQLVFLGAVVFFVAPCILIVFSYVRIAMAVFQIPSAKGRHKAFSTCSSHLTVVILFYGTVLGIYIRPPDSFSTQDTVATIMFTVVTPMLNPFIYSLRNKDMKETVTRLLHRGSKSS", "length": 313 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZLG9-1", "protein_name": "N-terminal Ras-GEF domain-containing protein", "gene_name": "AABR07047293.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFSCCVWTTEGSGLKKDKNEGQGGTWKFMLLSCLQCLWPFAQKEIDLTRDNQAQDHEDQGEHEYAPQVVTEPCRESRISADMVENLVNRLVSSLQGGDPFFIPAFLYGYRQFTTTQHVLDRLLKRFAYFYLGCEEDEQIKSSLCCFLDTWIDQYPEEFSQTILKKLKTYLTVNMPSSDLNLRVHMLLKELRQESNESEGKDDDSVSLPVTLLYKTASAADLSSSVEVGSHTSGDLDIEVWFPSQKVQPEPAYPHETETPQSTIKVISWD", "length": 269 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZMT2-1", "protein_name": "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3", "gene_name": "Ndufa3-ps1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAGRSSDFFKNAQAKEPVLVVSFSVWGLAVILPMISPYIKYAGVISKATPYNCPVPVRDNGNVPGVPSQPQERLSPSLERLKNL", "length": 84 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZNA3-1", "protein_name": "60S ribosomal protein L7a", "gene_name": "AABR07049918.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPKGKKAKGKKVAPAPAVVKKQETKNVVNPLFEKRSKNFGIGQDIQPKRDLTRFVKWPHYIRLQWQRAILYKQVKVPPAINQFLQALVRQTVTQLLKLAHKYRPETKQEKKQRLLAHAEKKAAGKGDVPTERPPVLRAGVNTVTTLVENKKAQLVVTAHDVDPIELVVFLPALCRKMGVPYCIIRGKARLGRLVHRKTCTTVAFTQVNSKDKGALAKLVEAIRTNYDDRYDEIRCHWGGNVLGPKSVARIAKLEKVKAKEFATKLG", "length": 266 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZNR1-1", "protein_name": "Elongin-B", "gene_name": "Elobl9", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEVFLMIRRKKTTIFIEAQELTTVLELKRIVQGILKRPPEEQLLFKDDQLLDESKTLRDCGFTSRVAKAQDPATVGLVFREDASEGLQIHPYSTPLLPSVMKTGTDSLE", "length": 109 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZNU6-1", "protein_name": "Olfactory receptor", "gene_name": "Or5p66b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSWLENGNHTTVAEFLLLGLTDDPVLRVILFTIILCIYLVTVSGNLSTILLIRVSSQLHHPMYFFLSHLASVDIGYSSSVTPNMLVNFLVERNIISYLGCGIQLSLVAFFGAAECFLLAAMAYDRFMAICNPLLYSTKMSTQVCILLVVASYIGGFLNASFAMVSFCSFLFCGPNIINHFFCDFAPLIELSCSDVSVYVIATSFSAGSVTMITALVIAISYSYILITILKMHSTEGRQKAFSTCTSHLTAVTLFYGTVTFIYVMPKSSFSIDQNKIVSVFYLLVIPMLNPLIYSLRNNEIKSALKKQIWRKTVS", "length": 314 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZPU6-1", "protein_name": "Large ribosomal subunit protein eL21", "gene_name": "LOC134485591", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTNTKGKRRSTRYMFSRPFRKHGVVPLATYMRIYKKGDIVDIKGMGTVQKGMPHKCYHGKTGRVYNVTQHAEGIIVNKQVKGKILTKRINVRIEHIKHSKSRDSFLKRVKENDQKEKEAKEKGTWVPLKRQPAPPREAHFVRTNGKEPERLEPSPYGFMA", "length": 160 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZQ96-1", "protein_name": "Large ribosomal subunit protein eL21", "gene_name": "LOC102550668", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTNTKVKRRGTRYVFSRPFRKHGVVPLVTYMRLYKKGDIVDIKGMGAAQKGMTHKCYHGKTVRVYNVTQHAVGIIVNKQVKGKILAKRINVWIEHIKHSKSRDSFLKQVKENDQKKEEAKEKGTWVQLSLQPAPPREAHFVRTNGKEPELLEPVP", "length": 155 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZQD9-1", "protein_name": "Developmental pluripotency-associated protein 3-like", "gene_name": "LOC120096627", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDKSSEKVDPVVNPETQMNDGSQREDEEDSPDDSEILQPETLVKVMKKLTLNPSAKPPKYHRHQRVRLRIKSQPVGNRSERIMREVQSAFPKTRVRTLLSVLKDPIARMRRFVRIEQRQRQLEGNERRDEPFRCLCTFCHYQRWDPSENAKIGQNQKN", "length": 158 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZQT0-1", "protein_name": "Glyceraldehyde-3-phosphate dehydrogenase", "gene_name": "AABR07071101.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MILCIKPSSTTKYCLNQCYLISCINKPNLLDGVNGIPLDIVAINDPFIDLNYVVYMFQYDSTHGKFNGTVKAENGKLVINGKPTTIFQERDLANIKWGDADAKYVMESTGIFTTMEKAGAHLKGGTKMVIISAPLADAPILKYDNSLKIVSNASYTTNCLAPLTKVIHDNFGIVEGLMTTVHTITATQKIVDGPSGKLWRGGHGAAQNINPETTGVAKAVGKVIPELNGKLTGIAFHVLTPNVSVVDLTCHLKKPAKYDDIKKVVKQASKGPLKGILGYTEDQVVSCDFNSNSHSSTFDARTGIALNDNFVKLISWCDNEYGYSNRVVDLMAYMASKE", "length": 338 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZTK7-1", "protein_name": "Uncharacterized protein", "gene_name": "AABR07012426.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSGDLEAKISGYTHISVQRFCYKWTISNFSFCMDGIRENITSPVFSLEGNEEVQWCLRIFPNGVDEESKDYLSVSLGLHSCPKSPVLAKVQFWIINAQGEKHQIKEIPNILSFSPKHQWGLRKFILREFLLSRRHGLLPEDQLILCCKVSVVGPSFSTPGHNMTPANKDPRQMLADDVGELWENSLFTDCSLVVAGQEFRAHKAILAARSPVFRAMFEHEMLESLTNRIEIHDIHLQVFKEMMAFIYTGKAPHLHSHSMATELLAAADMYDLQDLKVMCEDSLCRNLSVKTAVPTLMADLHSTELLKTRVMDFIILHASEVSETLEWKSMVESHPHLVEEAFGSLASMHYFFLEPSLKR", "length": 359 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZV50-1", "protein_name": "Small ribosomal subunit protein uS4", "gene_name": "Rps9l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLVARSWVCHKTYVTPRRPFEKSRLDQELKLIGEYGLRNKHEVWRVKFTLAKIRKAARELLTLDEKDPRRLFEGNALLRRLVRIVVLDEGKMKLDYILGLKIEDFLERRLQTQVFKLRLAKSIHHAHVLIRQRHIRVRKQVVNIPSFIVCLDSHKHIDFSLRSPYGGGRPGRVKRKNAKKGQGGAGAGDDEKKEK", "length": 195 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZWL0-1", "protein_name": "Ribosomal protein L32 like 1", "gene_name": "Rpl32l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAALQPLVKLKIVKKRTKKFIRHQSDRYVKIKRNWRKPRGIDNRVRRRFKGQILKPNIGYGSNKKTKHMLPSGFRKFLVHNVKELEVLLMCNKSYCAEIAHNVSSKNRKAIVERAAQLAIRVTNLNARLRSAENE", "length": 135 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4A176-1", "protein_name": "Golgi associated RAB2 interactor 5A", "gene_name": "Garin5a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPRLRTSARSPAPAVRMAISPSGPLGFTSPVTQPRREASPGVPTTQGRGVAMKGGRDLKPASGRADRPLAQAYAPCRPGRLQRHLLSGEFDQLRDFPIFESNFVQVTRFGEVANKVTMGVAASSPALELPDLLLLAGPDKENGHLQLLGLFPLQFVQLFVHDVSRQQLKVKFRTGRAFYLQLRAPPETRDCEFGRWVRLLYRLRFHSPTCAVPFTHEDTVPEESEDEDEVEEGQLQPPEVRAGPRAQGCWARKDGKGPVSCHRGQTRPAGLRTLGALIQPRSFQITKGPEIKPAQLRAREMDF", "length": 303 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4A9N2-1", "protein_name": "Olfactory receptor", "gene_name": "Or4a77d", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGQNNSVSEFILLGLTEDPAGQKTLFVVFLLIYIGTMVGNLLIVWTVIASPSLDSPMYFFLAYLSLIDALYSSTILPKLLIDLLCDKKTISLTACLVQLFVEHLFGGVEIFLLVFMAYDRYVAICKPLYYLTIMNQRVCVCLVVVSWIGAFAHALVQVFSVYKLPFCGPNIIDHFACDMYPLLGLACTDTYFLGLTVVGNNGAISVVVFMLLLLSYGIILNSLKTHSQEGRRKALSTCSSHIMVIVLFFVPCIFMYVRPVSNFPLDKFITVFYTVFTPMLNPLIYTLRNLEIKKSMEKLCRKIFTSDRIRISSCYS", "length": 316 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4AAM5-1", "protein_name": "Preferentially expressed antigen in melanoma-like", "gene_name": "Pramel", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDVKTPNKLLELAIHSLLNEESAAIQALEEIPRELFVPLFIAAFEGGHKNVLSAMVKVWPYYCLHIGSLSIQEPQHELLKAMIENLPVYPAPSSSSRGPKLRILDLRQDTDCRITCPEVSTKTPSCFYSCAYSDRSITKIERQLCCVNAECKTLLPRPVELLVDLSLDGSLMEKEFLVLLMYKIEESLGSLHVCCRDLQIDKLCKCKCTLKFLDLKCIDQLSVDRGSLSDITSILCRMIHLESLSLSNVTFRSLSGKVFKIFLSHLQRMEHLKELSLSSFCLKNHLDRVLRILPPGLDFLYLPFCDLSYRDFKFMSQSPQVTHLKLLNLSNNPMYWGDFEPFHTVLINLSGTLQHLEINHCLISDSAMSALIPALIRCTRLRVLGFASNPISMPMLVNIMHNLTPMKELKYVIYPIPVHCYERWHFQGSLDRQKLAIVQLQLKAMLELAHREDMNWITYCE", "length": 461 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4AAN9-1", "protein_name": "Similar to human chromosome 6 open reading frame 52", "gene_name": "C17h6orf52", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVETQSPGKECAVLPLWVLTVTSCPLPSAIREQLRVHHSLRCHRDNHYELLHSFYWLSCYSRGSTLSGNGLGPLCVTENPELLAGPWAIPEETTDPAENQEEDFLRDPNLHLNIEESDKEFMAVREELYDSLMNRRWHCLDTVLSNVPDELPQCEVF", "length": 157 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4ABB6-1", "protein_name": "Olfactory receptor", "gene_name": "Or13a27c", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "VNCIWHSKMVSPNQTVVTEFVLQGFSEHPSLRLFLTGCFMSLYTIALMGNIVIIALVTSSTGLHSPMYFFLCNLATMDIICTSSVLPKALVGLLSEENTISFKGCMTQLFFLVWSGSSELLLLTVMAYDRYVAICAPLHYSSRMSPQLCGALAMGVWSICAANASMHTGLMARLSFCGPKVITHFFCEIPPLLLLSCSPTYVNSIMTLIADAIYGGINFVLTLLSYGCIIASILRMRSAEGKRKAFSTCSSHLIVVAMYYSSVFFAYISPGSSYNPERSKFTSVLYSVLSPTLNPLIYTLRNKDVKLALGRILASFSH", "length": 318 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4ADX2-1", "protein_name": "Olfactory receptor family 4 subfamily A member 80", "gene_name": "Or4a80", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGQSKIVTEFVLLGFTQDPAGQKALFVMFSLMYIATMVGNLLIVGTVIVSPSLGSPMYFFLASLSLMDAVYSTAISPKLIVDLLREKKTISFRACISQLFIEHLFGGVDIVILVAMAYDCYVAICKPLHYLIIMNRRVCILFLVMAWAGGFAHALFQVLAVYNLPFCGPNIIDHFGCDIYPLLLLACTDTYLIGLTIIANGGAMCIVIFILLLLSYAIILRSLQNHSQEGRHKALSTCSSHITVFFLFFVPCILMYVRPVSSFPIDKSITVIYTVVTPVLNPLIYTLRNSEMKNSMEKLLQKILSPNRLRLLCCLYY", "length": 317 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4AEJ6-1", "protein_name": "Peroxisomal biogenesis factor 11 gamma", "gene_name": "Pex11g", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MALLNGLASALESYRGRDRLVRGSVGPWRDRSDLEFGQDSEMRKTGQRGGPKGTDIGRLVSYMRTSYLSLPNCWPYKCVLALQIRTLGYGCQLIGGVLVEQCPSRSEVGRRLLVVSAQLSHCRTVLRLFDDLAMFVYTKQYGLGAEEEDVFIRWLSVLSNMADQLYYPCEHVAWAADAKVLQVDSARWWTLSTAFWSLSLLLGAVKSLWTMLKLRQKLRSPTGHFASQLPRSKWRAVEARIWSEALTLLSNLADLANAVHWLPPGVLWAGCFPPWLVGLMGTISSILSVYQAARAGKQAEVDSP", "length": 304 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D6R901-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 21", "gene_name": "USP17L21", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEEDSLYLGGEWQFNHFSKLTSSRPDAAFAEIQRTSLPEKSPLSCETRVDLCDDLAPVARQLAPREKLPLSNRRPAAVGAGLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCHRHKGCMLCTMQAHITRALHNPGHVIQPSQALAAGFHRGKQEDAHEFLMFTVDAMKKACLPGHKQVDHHSKDTTLIHQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVQQALEQLVKPEELNGENAYHCGVCLQRAPASKMLTLLTSAKVLILVLKRFSDVTGNKIAKNVQYPECLDMQPYMSQPNTGPLVYVLYAVLVHAGWSCHNGHYFSYVKAQEGQWYKMDDAEVTASSITSVLSQQAYVLFYIQKSEWERHSESVSRGREPRALGAEDTDRRATQGELKRDHPCLQAPELDEHLVERATQESTLDHWKFLQEQNKTKPEFNVRKVEGTLPPDVLVIHQSKYKCGMKNHHPEQQSSLLNLSSSTPTHQESMNTGTLASLRGRARRSKGKNKHSKRALLVCQ", "length": 530 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "E0CXP6-1", "protein_name": "UMAP1-MVP12 associated (UMA) domain containing 1", "gene_name": "Umad1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFHFFRKPAESKKPSGPEPEADGFVLLGATANEVRCKTSEAEGSQALETGKEDTSSVTVSGPETENQTGQTLQNNSLTAELLSDVPFTLAPHVLAAQGTISDLPDHVLSYDVGDNLSRFWYDFTLENSVLCDL", "length": 133 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E0CZF1-1", "protein_name": "PRAME like 34", "gene_name": "Pramel34", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSGQTPPTHTLLTHEALIMSSLEELPTVVFPALFKEAFAGRHTNLLKAMVAAWPFPCLPVGPLMKKPNLETLQALLDGIDMRLTREFHPRRAKLQVLDMRNMYHAFWNIRADANDSDCKSKTLDEKQLVKVLPRYARRQRLKVIVNLSISSHFNKSKAYFLNWAKQRIGSLYFCCIKMRIWDPPDQVIRDIFNVFDPEHITELELNTDWTLLQLAHFASYFGHMKNLQKVFLAPLHKNTSPIINITNATEAKCVHKIISQFSQFNCLQHIFMKHVHFLRDYMNQVLGCLMTPLETLSITQCLISQRDFDLFSCSQNLFKLKHLEIRGMILYALDLMPLRVLLEKVADTLEILDFQWCRMKDSQINALLPALSQCTQLNQINFYNNDFSMCTLKALFQHTANWSKMNVEQYPAPLQCYSELGHVSVERFVQLCQELMYTLRAIRQPKSISFATDNCQKCGKPCVYDQGPILCSCFQ", "length": 475 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E1B8K9-1", "protein_name": "40S ribosomal protein S6", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MKLNISFPATGCQKVIEVDDERKLRTFYEKRMATEVAADTLGEEWKGHVVRISGGNDKQGFPMKQGVLTHGRVRLLLSKGHSCYRPRRTGERKCKSVRGCIVDANLSVLNLVIVKKGEKDIPGLTDTTVPHRLGPKRASRIRKLFNLSKEDDVRQYVVRNSLNKDGKKPRTKAPKIQRLMTPRVLQHKRRRIALKKQRTKKNKEEAAEYAKLLAKRMKEAKEKRQEQIAKRRRLSSLRASTSKSESSQK", "length": 249 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "E1BBD9-1", "protein_name": "RNA polymerase II subunit A C-terminal domain phosphatase SSU72", "gene_name": "LOC112445820", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MPFLPLRLAVVCSSNQNRSMEAHNILSKRGFSILSFGTGTNMKLPGPARDRPNVYDFRAMYDDVYKDLLRKDKERYMQNGVLRMLERNMEKEMPRPERFQECKDLFDLILTCEERVYDQVVEDMNSGEQETCQPVHVINVNILDTNKEATLGAFLICDLCQCVQLMGDMEDRIGELLQAFEEKSGRSFLHTVCFY", "length": 195 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "E1BLY1-1", "protein_name": "Small ribosomal subunit protein uS8", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MVRMNVLADALKSINNAEKRGKRQVLIRPCSKVIIRFLTVMMKHGYIGEFEIIDDHRAGKIVVNLTGRLNKCGVISPRFDVQLKDLEKWQNNLLSSRQFGFIVLTTSAGIMDHEEARRKHTGGKILGFFF", "length": 130 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "E7F638-1", "protein_name": "Moesin b", "gene_name": "msnb", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSINVRVTTMDAELEFAIQSSTTGKQLFDQVVKTIGLREIWYFGLQYQDSKGFSTWLKLNKRVTAQDVRKENPLLIKFRAKFYPEDVAEELIQEATQRLFFLQVKEAILNDDIYCPPETAVLLASYAVQMKHSDYNSEHHIPGYLCRDKLLPQRVLEQHKLTKEQWEQRIQVWHEQHKSMSREDAMIEYLKISQDLEMYGVNYFSIKNKKGSELWLGVDALGLNIYERSDKLTPKIGFPWSEIRNISFNDKKFVIKPIDKKSPDFVFYAPRLRINKRILALCMGNHDLYMRRRKPDTIEVQQMKAQAREEKNKRQQERALLENEKKRRENAEKETEKIARETMELMERLRQIEEQTKKAQEELEEQTKRALELERERKFAQEEAEKLEKDRRIAEDVKTALLQQSENQTKNKDNLATELAELTSKINLLEDAKKKKEDEARKWQRRAIMVEVDLEKTKEELKSKLIGVHIQATSQTENDHDENDESSAEASAELTSTGSFRDRSEEQRITETEKNEPLQKRLQALSSELADARDDSKKTANDLIHAENVRLGRDKYKTLRQIRQGNTKQRIDEFESM", "length": 577 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "E7FA22-1", "protein_name": "Protein tyrosine phosphatase type IVA 3", "gene_name": "ptp4a3b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAWLNGLYPVEVCYNSMRFVITHNPTNQTLDTFIEDLKRYDAKTVVRVCESTYDKTPLEKHGITVMDWPFDDGAPPPTKIVDDWISLLKKSFSEDPGCCVAVHCVAGLGRAPVLVAVALIEGGMKYEEAIHLIRLKRHGAFNSKQLTYLEKYRSKKRLRFKDPFKHRSKCWLM", "length": 173 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "E7FE27-1", "protein_name": "Beta-1,4-N-acetylgalactosaminyltransferase", "gene_name": "b4galnt4b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MRMRFPLKKIRKQFKLLLLLVLLMFAIGFTYLHINQGKAIKLHFNYGKDMERQAEGIGSSPKKHLSSSINPFEHGDAADSQEDGWGGEELNESAQESRANAEMHTLLAQKFLGLPWKPEYKGQANLHVFEDWCGSSVSQLRKNLHFPLYPHTRTTVKKIAVAPKWKNYGLRVFGFIHPYKDGDFQFAIASDDNSELWLSSDESPLNARLLVYVGQHGSEWTAPGEFSKFRSQTSKPVRLMSSRRYYFEVLHKQDDRGSDHVEVGWRPFLPGQKFDVIDSAYISLYTDESSLKMNSVHHIPQTLASHSLALQIYHRTETHTADMLKPDPRDTFYKIPMIDQSRLENVLPSCVYSPTYVVKDFPIARYQGLQFVYLSYVYPNDFTRLTHMEKTNKCFYRESPVYLEKFGFYKYMKMDEEEDDQPVFFPKPDDFLEEEEGVDPEEAINSSNRPVKRSGPSYQTSRITAATASSKPDRLDGGSKSSVFQQEKQYVQFKEQERSKKRTKGERFYRHSQVVDDEMTEIRQVKGSTGVLESQSGSLNEQTGPSEENGDSQTLSLVQRGRSLAWVLPDPALQSESKLIETASPTVKERSPFKLPHLYVLANRILGNAGKPVVEKESNSNKIYITRPRPPVSRPKPPVEVFPGVFLYQSRKSKRLVDLSSKWRSLKTQAAASAPWANFPLMDHKTSTQSALLKQSHLSSPTEPGPHNKGDPTASISDPDSVPPSSSEKRDHPGLNSSSQPPEEEPTKISEMAEGLDVAPQSRGLEEGEMSEYSYEEAEVRPHLAEEAINWQRTFSVNPVDFELLRSDWNDLRCNVSGNLQLAENEVIDVISQFMERLNERNRGIYTLARIVNVEKRRDSARGNRYLVELLLMEGGKRLVRLSEYIYLLLHRSRFEEGIESREGTVPSSHRTPSKIPLPSGSSAQTHTTTPWSTSWAKPLLCQPIMLQWRHDVMVHFVVPVKNQARWVQQFISDMELLHRETKDENFSVIIVDFQSDDMDVEQALKESTVPRYEYLKREGNFERSSGLQMGVDTIEDSHSIVFLCDLHIHFPHNILESIRKHCVEGRLAFAPIVMRLDCGSSPLEPDGFWEVNGFGLFGIYKSDFDKIGGMNTEEFKDHWGGEDWELLDRVLQNGLEVERLRLRNFYHYFHSKRGMWNVPVKRASQG", "length": 1167 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "E7FFR8-1", "protein_name": "Ubiquinol-cytochrome c reductase complex assembly factor 5", "gene_name": "uqcc5", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLRKSQNLKYMLSLVPGKKRFGVYRFLPVFFCIGGVMEWIMINVRIGRETFYDVYRRKQSERAYQQKTEEGLIMLTDSQAK", "length": 81 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "E9PUW9-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r143", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQILLLCQFGVGTVANVFLFFHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMSAFAPKTPPNELKCKLEFFSHMVARSKNLCSTCVLSIHQFVTLVPVNRGKGKLILRASVPNLWNYSCYSCWFYSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGMVFLQFSHDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQDARGQAETRATHTILMLVVTFVSFYLLNCICIIFHAFSIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 307 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PUZ0-1", "protein_name": "Apolipoprotein L 11b", "gene_name": "Apol11b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDWNEISEDIRKVECRTFEKVIDNATEDLITDLRSLITEDGAWNGFVEAVELSSEEGEALRDALKERLAQDPTDENDRPQREQQKERFLREFPQLKKKLEDHIRKLRDLADKFDQVHKDCTISNVVSTSASAASGVLALLGLVLSTVTAGASLALSASSVALGATSSVSSFTTTVVEDSMTLSYESEARNLIGASMNVLEEILSIMPKITCKFYNTVADLVKAFKTLKGQIQTIRRARSISRRGAQARNLTSTGRSSGQGVSQMTRGARIRAGVFTSVFLGWDVYDLVTKQRICMMGEKQSQVEHCGTWLASWRRTFRNLSRSTMLCSQTCLSDALP", "length": 337 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PV04-1", "protein_name": "Eukaryotic initiation factor 4A-III", "gene_name": "Eif4a3l1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MATTTRMATSGSARKRLLKEDGMTKVEFETSEEVDATPTFDTMGLREDLLRGIYAYGFEKPSAIQQRAIKQIMKGRDVIAQSQSGTGKTATFSISVLQCLDIQVRETQALILAPTRELAVQIQKGLLALGDYMNVQCHACVGGTNVGEDIRKLDYGQHVVAGTPGRVFDMIRRRSLTTRAIKMLVLDEADEMLNRGFKEQIYDVYRYLPPATQVVLVSATLPHEILEMTNKFMTHPIRILVKRDELTLEGIKQFFVAVEREEWKFDTLCDLYDTLTITQAVIFCITKRKVDWLTEKMREANFTVSSMHGDMPQKERESIMKEFRSGASRVLISTDVWARGLDVPQVSLIINYDLPNNRELYIHRIGRSGRYGRKGVAINFVKNDDIRILRDIEQYYSTQIDEMPMNLADLI", "length": 411 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PVP9-1", "protein_name": "Predicted gene 4884", "gene_name": "Gm4884", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSENLQSSPFFGTESTLHPSLPLLSNSKQPAGTVCNFSRVSTPDVSSAWLLPSASSTSLQPLMVVQMETSLGLPPSGQTYCQLQSPELCNTCVQVSQIRPPAVNGDKALTAPIHSPSQFLALPPAPSLEQPENKTMPEIKEGTKENQDTPVLTLEHPDLQQPLHCTDTESLRQKPDSDNAHLGCICMGPKELVGLENEIGSSFDFKDITRFGADIQLPQLLNTLTDIDQDQSCENWRVTSGLFDQVRENKHKSFELLEGAPQAKFQHWDLVEGEGAVGVAGASDRAIDNMAKHPEGKAPKGPPSKNRRARKQEQERPSGPENKSKKTQELKQSRNRVKAEKEPSIPKTKRKRNPPELSQNSFKKPRTNLAMHMLESVQVFHPLGKKSEKKTGISSFRGLRTFTSNKDSGPGSVTTTVLNMPCESQGPPKSPGKVQSAESSVGKDCLSPSQYELPPAGKVKLVPLPFPTLDKPQSRPASRKPLSLALRRPTAVYPVQHHSHSVQPTTLRPAQPPPASSSLIASAKPAPPISSSATGPNVTNPNQSSAVPQLATSRPVPYRASSHTSFQRELVSAARNKVPSPPRPVPYRASSNTSFQRELVSAARNKVPSPPKPQTQYLLHDFSRQPIPWKKVDILGPVVSQPITKEQRPEREAMKRRSQQERENAVKNPSTGKLQIFLQRERDMEISQYYGYAM", "length": 694 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PVW0-1", "protein_name": "Major urinary protein 8", "gene_name": "Mup8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKMLLLLCVGLTLVCVHAEEASSTGRNFNVEKINGEWHTIILASDKREKIEDNGNFRLFLEQIRVLENSLVLKVHTVRDEECSELSMVADKTEKAGEYSVTYDGFNTFTIPKTDYDNFLMAHLINEKDGETFQLMGLYGREPDLSSDIKERFAQLCEEHGILRENIIDLSNAMDLVPEHVLVLTRQIAASRPENEEWPEPPVLSGDFSPGLHHHPFLSIQHPQYKFCDLHSILSH", "length": 235 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PVZ7-1", "protein_name": "Olfactory receptor", "gene_name": "Or8b3b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKYFCLPRFSIISMLTGNGSFVTEFVLAGLTDRPELQLPLFYLFLIIYTVTVVGNLGLIILIGLNPHLYTPMYYFLFNLSFIDLCYSSVSSPKMLMNFVFEKNSISYEGCMTQLFFFLFFVISECYMLTSMAYDRYVAICNPLLYKVTMSPQVCSMLSFASYGMAFAGASAHTGCMLRLIFCNANVINFYLCDILPLLQLSCTSTYVNEVVVLIVVGINITVPSFTILISYVFILANILNIKSTQGRSKAFSTCSSHIMAISLFFGSGAFMYLNHSGSMNQGKISSVFYTNVVPMFNPLIYSLRNKDVKIALKKVMMRVHSRFIS", "length": 325 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PW18-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r257", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSVHDKSVKTTEEVALQLLLLCQFGVGTVANVFLFVHNFSPVLTGYKQRPRQVILSHMAVANALTLFLTIFPNNMMAFAPKTPPNELKCKLESFSRLVARSTNLCSTCVLSIHQFVTLFPLSRGKGKLILRASVQNLASYSCYSCWFFSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGIVLQFAHDATFMSIMIWTSVSMILLLHRHCQRMQDILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNCICIIFHAFFIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 306 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PW59-1", "protein_name": "Olfactory receptor", "gene_name": "Or8b50", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALANGSFVTEFILLGLTDQPDLQMPLFLIFLIIYLITAFGNLTLIILIVLNSHLHTPMYFFLFNLSFIDLCYSSLITPKMLMNFVLEKNIISYMGCMTQFYFFGFFAISECYVLTAMAYDRYVAICNPLLYSVAMSPKMCSYFILGSYFMGFSGAMIHTGCVMRLTFCDGNTINHYFCDLLPLLQLSCTSTYVNEIELFIVTGKDIIVPTVIIFASYGFILSNILKIRSTSGRSKAFSTCSSHIIAVSMFFGSSAFMYLKPSSAVSMNEAKFSSIFYSIVVPMMNPLIYSLRNKDVKVGLKKTLSRMFSHNLISL", "length": 316 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PXC3-1", "protein_name": "Cytochrome P450, family 2, subfamily c, polypeptide 69", "gene_name": "Cyp2c69", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDPFVVLVLCLSFMLLLSLWRQRSARRNLPPGPTPLPIIGNYHLIDMKDIGQCLTNFSKTYGPVFTLYFGSQPIVVLHGYEAIKEALIDHGEVFSGRGSFPFFDKVSKGKGIGFSHGNVWKATRVFTVNTLRNLAMGKRTIENKVQEEAQWLMKELKKTNGSPCDPQFIIGCAPCNVICSIVFQNRFDYKDKDFLSLIGKVNECTEILSSPGCQIFNAVPILIDYCPGRHNKFFKNHTWIKSYLLEKIKEHEESLDVTNPRDFIDYFLIQRRQDKGIEHMEYTIEHLATLVTDLVFGGTETLSSTMRFALLLLMKHTHITAKVQEEIDNVIGRHRSPCMQDRKHMPYTNAMVHEVQRYVDLGPTSLVHEVTCDTKFRNYFIPKGTQVMTSLSSVLHDSTEFPNPEVFDPGHFLDDNGNFKKSDYFVPFSAGKRICVGESLARMELFLFLTTILQNFKLKPLVDPKDIDTTPKYSGFSKIPPKFQMCFIPVE", "length": 491 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PXM9-1", "protein_name": "F-box and WD-40 domain protein 24", "gene_name": "Fbxw24", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEIHLSSFPMMEIFSYLDAYSLLQVAQVNKNWNALASNDFLWRKLCQERWLFCDMVTLQLLGKETWKQFFVYRTWQEHVKSRAIPEDFTYKEIPLECGVRGYAGYISGCALTRNGQGKSVVCMVSSKNKISTWDISESVITWVSPVQPASIKLLTTLPDMHIAVTVDIQSTIKLWDCHNREALATNNLESPCKSLKAVISKDGPIVLAGDILGNLYIFRIPDLHLISTVNVFPCGFDKIDCSPQKKWVLLSQNHPCIYPKVFYMSSLLRTSEFSDPVSTVLEFSLCKRAFWTPRREDRITLMSRRGRPIVTRFETFDMKLEENGNKTIVKGDLVASFSLQDYNENPKWMGVSDKSVIVCSTGSSLLLFSMKGLHLQTFQYSPEMIVRLWVDPVHVIITCNDGSIDVYMWEERSLLLKMCYRLQNGRHLPPFGFIKNLLCDDVSIVQLMIDRQGPCFLMAYTLNICS", "length": 466 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q069-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r157", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQILLLCHFEVGTVANVFLFVHNFSPVLTGYKQRPRQVILSHMAVANALTLFLTIFPNNMMAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSVHQFVTLVPVNRGKGKLILRASVPNFANYSCYSCWFFSVLSNIHIPIKVTGPQIIDNNTYDKSNLFCSTSGFIVGIVFLQISHDATFMSIMVWTSVSMVLLLLTPNQDARGQAETRATHTILMLVVTFVSFYLLNCICIIFHAFSIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPNDPCSVLFKC", "length": 297 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q0V3-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r68", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGVAIIKENQTQSKMDFWNMGIKILFLSQTTTGILGNFSLIIYYVVNYIVHTLKPTDLILMHLMTSNALMVLSTGVLHTMAAFGLAHLLNDLGCRLILYIQRVGRSTSIGTICLLSIFQAITISHRVSCYKGQKIKSSKYIGYSISLLWVLHMFLNFILFVDIFIKRNRNNMTSDRDFKYYSIVERNEFSDSLYVALVVCPEIFSSVLITCSSGSMIGILYRHKQRVQHIRSFHVSSRNSPEWRATQNILVLVSTFLAFYTLSSVLQGCIALLNNPNWWLVNITRLTSLCFPTFAPCVLMSHYSFMPRFSLVWTWNKTS", "length": 319 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q1C7-1", "protein_name": "Spermatogenesis associated glutamate (E)-rich protein 4A2", "gene_name": "Speer4a2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWMGETREGRKDADLPSKSNEGRRRWTWRMWMAHRQKTSPVPVTSKKQFEKEEKELIKKIQLTTEETNELRDRLIYVTEGSMNKRPYHRQTRHYKELKLKEKEIMTFLHNLEMENMEARENKQELKKEKNFYRNLHTRILLEENLIKKKLAILQQESKEIHADWAIIHQRLVELNLSGKDEQEKTSNLETQEHQVSEAARELGLATAEEDSILQNELPCQEAPAEHHPQHPPSSSDESSSDESSYSTCPEWE", "length": 252 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q1N7-1", "protein_name": "Predicted gene 8126", "gene_name": "Gm8126", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLRRLFHRENGNQGETRPRQKESAIPSCKNRRMKSFWGRHMSAGKTSSQNCNITNHMKNRNKLDDMKFYIRKINAERLELFRILDIDMNTDLNYRMNIEFTIIKSQHEKTMLDMEKITQSINDTIEKYKEFIEDKDSYSFMHTYLLKECNQLKEKVRMLLNENRKLLVEQADQEASYGEENRFCHESSKNIHPKY", "length": 198 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q328-1", "protein_name": "RIKEN cDNA 5430401F13 gene", "gene_name": "5430401F13Rik", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASSRILLVLLSIALLALTSAQRVNEDDGSALQEEDALEIGDSNQQHDDIHERLNEIKNHFQDQISQHGKEAIKSKKGKNGPRSRRSSDDDNLEVQDHQSGNEQAGGGQGGRGRSELKGQNGKGSQKGKKGKGGQQEQKGKGGQQKQKGKGGQKTKRGKGGQRSQQDNVQEVYQE", "length": 175 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q346-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r160", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSLKTTEEVALQLLLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILIHMAVANALTLFLTIFPNNMSAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIHQFVTLVPVNRGKGKLILRASIPNLWNYSCYNCWFYSVLSNIHIPIKVTGPQITDNNTDSKSKLFCSTSGFIVGMVFLQFAYDATFMIIMVWTSVSMVLLLHRHRQRMQHILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNFICIIFHAFSIHSHLFIRLVSVVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 307 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q366-1", "protein_name": "Spermatogenesis associated glutamate (E)-rich protein 4f2", "gene_name": "Speer4f2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTMCVRLRRLFQRANVDGRETREGSMDAGLPCERNEGRRRWTWRMWMAHRQTSSPVPVTSNQFEKEEEELMEEIQLISQEKNGLRDYLNLTLGSKITRLNQSYEELKLKQKELMTLQHDLEMATMEAREENEELKKEINFYSNLHSRALMENNLIKKKLMTLQQESKEVQAEWASIQQHLDVNLSGKDEQENNSILDTQEHQVSETARELGLATDQEDSILQDELPPQEAPAEELSPQEAPAEELPPQEAPAEQLPPQEGPAEELPPQESPAEHHLQHPQSFSDESSYITYPEWE", "length": 295 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q3G0-1", "protein_name": "Zinc finger and SCAN domain containing 4B", "gene_name": "Zscan4b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASQQAPAKDLQTNNLEFTPTDSSGVQWAEDISNSPSAQLNFSPSNNGCWATQELQSLWKMFNSWLQPEKQTKEQMISQLVLEQFLLTGHCKDKYALTEKWKASGSDMRRFMESLTDECLKPPVMVHVSMQGQEALFSENMPLKEVIKLLKQQQSATRPIPDNAQMPVDTTQDRLLATGQENSENECNTSCNATEVNVGESCSGNEKDSLLITQKEQNHEHEEGNVVCQFPRGARRASQDTSSHHVDFPSALTPADVPMEEQPMDLSRENISEDKNNCYNTSRNAATQVYSGDNIPRNKTDSLFINKRIYHPEPEVGDIPYGVPQDSTRASQGTSTCLQESLGECFSEKDPREVPGLQSRQEQPISDPVLGKNHEANLPCESHQKRFHRDAKLYKCEECSRMFKHARSLSSHQRTHLNKKSELLCITCQKIFKRVSDLRTHEIIHMSEKPFKCSTCEKSFSHKTNLKYHEMIHTGEMPYVCSLCSRRFRQSSTYHRHLRNYHRSD", "length": 505 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q4E0-1", "protein_name": "RIKEN cDNA 5031410I06 gene", "gene_name": "5031410I06Rik", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRVNVDGRETREGRKDADLPSERNEGRRRWTWRMCMAHRQTTSPVPVKSKKQFEKEEKELIKKIQLTTEETNELRDRLIYVTEGSMNKRPYHRQTRHYKELKLKEKEIMTFLHDLEMKNMEARENNQELKKEKNFYRNLHTRILLGENLIKKKLAILQQESKEIHADWAIIQQRLVELNLSGKDEQEKTSNLEAQENQVSEAARELGLATAEEDSILQNELPCQEAPAEHHPQHPSSSSDESSSDESSYSTCPEWE", "length": 267 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q501-1", "protein_name": "Predicted gene 2237", "gene_name": "Gm2237", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLLRLFQKENVDEGETRPTEKEEGILSHEKGRRKWFWRRHRSARNTSTQNSKMTKKRSKINELEELKLDMRKISNDMEEMCGILNLYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLHENVRILLNENRRLLVEQAGHKCPVGKKRGSLRRPARTSVSQVPRNSSPAESRTWH", "length": 211 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q5G7-1", "protein_name": "Oogenesin-1", "gene_name": "Oog1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVICLHCPDQDDSLEEVTEECYSPPTLQNLAIQSLLRDEALAISALTDLPQSLFPVIFEEAFTDGYIGILKAMIPVWPFPYLSLGKQINNCNLETLKAMLEGLDILLAQKVQTSRCKLRVINWREDDLKIWAGSHEGEGLPDFRTEKQPIENSAGCEVKKELKVTTEVLRMKGRLDESTTYLLQWAQQRKDSIHLFCRKLLIEGLTKASVIEIFKTVHADCIQELILRCICIEELAFLNPYLKLMKSLFTLTLDHIIGTFSLGDSEKLDEETIFSLISQLPTLHCLQKLYVNDVPFIKGNLKEYLRCLKKPLETLCISNCDLSQSDLDCLPYCLNICELKHLHISDIYLCDLLLEPLGFLLERVGDTLKTLELDSCCIVDFQFSALLPALSQCSHLREVTFYDNDVSLPFLKQLLHHTALLSQLIYECYPAPLECYDDSGVILTHRLESFCPELLDILRAKRQLHSVSFQTTKCSKCGGCYIYDRHTQCCRFVELL", "length": 496 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q6D7-1", "protein_name": "RIKEN cDNA 1700024B05 gene", "gene_name": "1700024B05Rik", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MESHDNPVSAGRTSSQNCNITNHMKNMNKLDDMKFYIRKINAELEELFRILDIDMNTDLNYRMNTEFTIIKSQHEKTMLDMEKMKQSISDSIDKYKEFIEDNDSYSIRHTHLLKECNQLKEKVRMLLNENRKLLVEQADQEASFGEEKSSVMRPARTYIPSAKQQQL", "length": 167 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q7M8-1", "protein_name": "Predicted gene 5796", "gene_name": "Gm5796", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLLRLFQKENGDEGETRPKKKEEGILSHEKGRRKSFWRRHRSARNTSTQNSKMTKKRSKRNELEELKLDMRKISNDMEEMCGILNLYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLNENVRILLNENRRLLVEQSGHKCPVGKKRGSLRRPARTSVSQVPRNSSVI", "length": 205 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q8A4-1", "protein_name": "F-box and WD-40 domain protein 28", "gene_name": "Fbxw28", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEIHLPSVPMMEILSYLDAYSLLQAAQVNKNWNELASSDVLWRKLCQKRWLYCYMFTLPLHGLETWKQFFFDKTWQEHAKTRAKPEDFTYKEFPVEFEFRAHPWYISRHGLTRNGQEKSAVCMTSMNRISTWDIHEGAMTWESPKQPSYIVWMTTLPEMQIAVTIDMQSTIKLWDCHNKEVLASKTGLFFGCKLLQSEFTKDGPIVLVGDACGNLYIFRIPDLHLISKVNVFPYSIDELYFSPQKKWVFLIGHRLNDLTKVFYMSSLLRPSEFSAPVSTVLKVPVIRKVFWTPRREDRITLMSLILPKNITKFDTFDMKLEGIGNKVTIQGYLTASFSLAEDEGRPDYFGVSDKDVIVCSTRFSLLLFDINGLRLQTFHYCPEEIWRLWVDPVHVIVTCDAGSLDIYAWEKRSLLLRKCYRLRNRNYQQMSGYIIKTLCDDMSIISVANNSPKPCCLMAYTLSVCS", "length": 466 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q8I6-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r55", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEMLALQILLLCQVVVGTVGNILLFVHNFSPILTDSRLRPIQVILINLAVANAFMLLLLTYSHDMIDLVPKNPPTDLKCKLAHFFHMVARGTNMCSTCVLSTYQFVTLVPGNWARVMFREISPKVVRYSCYSCWLFSVLNNAYIPMNVRGPKKSHNDSDSQGKRMCSISVVNVDMNYLQFSYDIIFIGIMVWTSVSMVIHLNRHHQRMHYIHNPNQSNRGHAETRAAHTILMLVVTFVSLYILNCICVLFHVSFVESRRWLRNVIEFLALSFPTISPLLLIFRDPRGPCSLYFNVGLEIHVTGKVITEEQ", "length": 310 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q8L6-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r132", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQILLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMMAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSVHQFVTLVPVNRGKGKLILRASVPNLWNYSCYSCWFFSVLSNIHIPIKVTGPQIIDNNTYDKSNLFCSTSGFIVGIVFLQISHDATFMSIMVWTSVSMVLLLLTPNQDARGQAETRATHTILMLVVTFVSFYLLNCICIIFHAFSIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPNDPCSVLFKC", "length": 297 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q8T0-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSFKNVLYFQTGLGVLANTVLLFFYVFIILGHRPKPTDLISCQLSFVHIMVVLIGGDILLADIFESLNIGNDFKCKTTFYLFRVMRGLSICITCLLSVFQAVTISPNTSVLAKFKQKVKKYMTHVFLCIWFFNLSFSTNQIFYVGGFTNVSETNQMQVTKSCSLLPMNYIIRGLIFTISISRDVFLVGVMLTTSVYMVIFLFRHQRQCKHLHSFSHPRESPEKRATQTIMLLVSFFVVLYWMDFIISFTSEMLRMYDPVILTLQKFMMYAYPTITPLVQISSDNRIIIMLKNIQSKCHPSFSLKDFFFFI", "length": 311 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q8V7-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r173", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSALNKALKTTEEVALQIILLCQVGIAAVANILLLVHNLSPNFAGPQLRPKHVILAHITVGNLLIILLTGFPSNIIVFVPRNPLNDLNCKLEYFIRLVARSANMCTTCVLSTYQFIVLVPGKWSRMILRGNTSTFVHYSCNSCWIISVLNNVYIPIKISGPWNTDNDTDLNSKWVCSMSGFELVMVFLRFVHDTMFISIMVWTSVSMMLLLYRHHQSLKHIHRSNGSLGLQPEARAAYTILMLVVTFVCFYLLDCMCIFFHISFVHFRVWLRHVNEILAASFPTLSPLMLIFRGPKKISAKGINTENAFINSH", "length": 313 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q9N3-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r152", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQILLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMSAFASKTPPNELKCKLEFFSHMVARSKNLCSTCVLSIHQFVTLVPVNRGKGKLILRASVPNLWNYSCYSCWFYSVLSNIHIPIKVTGPQITDNNTDSKSNLFGSTSGFIVGMVFLQFSHDATFMTIMVWTSVSMVLLLHRHRQQMQHILTPNQDARGQAETRATHTILMLVVTFVRFYLLNCICIIFHAFSIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 307 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9QAN3-1", "protein_name": "Predicted gene 1979", "gene_name": "Gm1979", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRANVDGRETREGRKDADLPPESNEGRRRWTWRMWMAHRQKTSPVPVTSKKQFEKEEKELIKKIQLTTEETNELRDRLIYVTEGSMNKRPYHRQTRHYKELKLKEKEIMTYLHELEMKNMEARENKQELKKEKNFYRNLHTRILLEENLIKKKLAILQQESKEIHADWAIIQQRLVELNLSGKDEQEKTSNLETQEHQVSEAARELGLATAEEDSILQNELPCQEAPAEHHPQHPPSSSDESSSDESSYSTCPEWE", "length": 267 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9QD93-1", "protein_name": "Granzyme K", "gene_name": "gzma", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDICRNLIVFHFLVFTFFKVTVCSDVSIVGGKDVKKALSWMVSIQVNQNHKCGGILIHKEWVLTAAHCKEDSYSSVTVLIGSLSLSKGSQRIAIHNYEIPETFNKKTKKDDIMLIRLSKKVKAKPYKIPKKEKDVQPGTKCVVRGWGTTDYKGKQASDKLQMLEVLVVDRVQCNRYYNRNPVITKDMLCAGNTQQHRGTCLGDSGGPLECEKNLVGVLSGSHGCGDPKKPTVYTLLSKRHITWINKILKQQFNSTRF", "length": 257 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "E9QLQ1-1", "protein_name": "Defensin, alpha, 35", "gene_name": "Defa35", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKTFVLLSALVLLAFQVQADPIHKTDEETNTEEQPGEEDQAVSISFGGQEGSALHDELSKKLICYCRIRGCKRRERVFGTCRNLFLTFVFCCS", "length": 93 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F1LPT0-1", "protein_name": "Gap junction protein", "gene_name": "Gjc3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MCCSFLRQLLARESQHSTPVGRFLLPVLVGFRLLILVSSGPGVFGNDENEFMCHLGQPGCKTICYDVFRPLSPLRFWAFQVILMAVPSAIYVAFTLYHVIGYWEVPGRNKEQEAQICKGGRCKDVSGAMSLKLLWAYVAHLGVRLVLEGAALGVQYHLYGFKMPSTFICREDPCIGSTTCFQSHPSEKTILLNTMFGISGACLLFIFLELVLLGLGRVWKTYRHKLPLFKNLSTSERSVRHKDTTDDLSVVETKEPF", "length": 257 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1LT33-1", "protein_name": "Cytochrome P450", "gene_name": "Cyp2b14", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MELGVFLLLTFTVGFLLLLASQNRPKTHGHLPPGPRPLPFLGNLLQMNRRGLLRSFMQLQEKYGDVFTVHLGPRPVVILCGTDTIREALVDQAEAFSGRGTVAVLHPVVQGYGVIFANGERWKILRRFSLVTMRNFGMGKRSVEERIKEEAQCLVEELKKYKGALLNPTSIFQSIAANIICSIVFGERFDYKDHQFLRLLDLIYQTFSLMGSLSSQVFELFSGFLKYFPGVHKQISKNLQEILNYIDHSVEKHRATLDPNTPRDFIDTYLLHMEKEKSNHHTEFHHQNLVISVLSLFFAGTETTSTTLRYSFLIMLKYPHVAEKVQKEIDQVISSHRLPTLDDRIKMPYTDAVIHEIQRFADLAPIGLPHRVTKDTMFRGYLLPKNTEVYPILSSALHDPRYFDHPDTFNPEHFLDANGTLKKSEAFLPFSTGKRTCLGEGIARNELFIFFTALLQNFSLASPVAPEDIDLTPINSGAGKIPSPYQINFLSRCVG", "length": 495 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1LYQ4-1", "protein_name": "Alpha-1-B glycoprotein like 1", "gene_name": "A1bgl1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDLLVLLEPLASLTLTCKVCEPSKDLHRILHLSSMETACTLSLALPPTLPSASLIFSASGVHTLILLRVRLNHSLILLSLIHTGPLPRPWLSANPVPWITPGLRTFLLCQGTVRDVVFMLRREGDDGNKEKEQGIFQVHEPGNYSCNYYTNTEYTPSKPSGTVTIKEYVIPPPPMLTSLESSTVDEPEMTQMSLLCVAPLSDVEFQLRQGEREMKVLIVSTSPERASFYLKLSDMGDHSPFTCRYRLNRMTAWSEDSKPVQLMWSDETLPEPVLTVEPSPHQSFEPGSTVQFRCTAPKAGLRSEAGLRFGLHLEDLYDHRLLQTQKSSGNETVFQLRNVSATDSASYSCIYTELTPPYSGSAPSDFVILRVNGPPPPPKLQALWTGKVFAGHDVVLRCQSDVTGVIVELLRDGKFVPYRILRVLNNYSDLGLHSVGPQHTGNYTCRYTSWLPEPVQSEPSNPVELLVEGMASGVVVVGFCLLIFPGLCILVNCAI", "length": 495 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1M6N1-1", "protein_name": "Zinc finger protein 945 like 1", "gene_name": "Zfp945l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTASLVNVSKCLLTFRDVAVEFSMEEWECLNYSQKTLYRDVMMENYNNLLFVENHCKYKKVLDQDPNSIVHNVNIYEKAYECNELVKMTHESSQGTPFKTKHKDASLQISTLNRQKIGNTRDEPCKFKDCINFLNVFVIRQNQRIYIGEKEPTTIEYENHYNSKHEVMLKQSNSTGNKPHIFRKYGQCFKIYSSFSRYQNDHTSEKFYKCIKCRKSFLHLSQLKVHYKIHYRKYPCKCTACSKCFYHTFGFKRHYSIHPEVNTYKSSDCDKSFIYYSSLRKHQKIFGGERHYECNEGLRSLYTVFQPVYYYIPHIGEKAYKCSECEKCFTRKYHLTVHQRIHTGEKPYKCGECDKCFTRKYHLTDHQRIHTGEKPYKCSECKKCFTRKYHLTDHQRIHTVEKPYKCSECGMSFMKKYHLRSHQSIHTGEKPYNCSECDKGFTYKGHLRRHQKIHTGEKPYKCSECAKCFTENSKLRRHQRIHTGENLYKCSECDRCFIENNKLRSHQKVHIGEKPYKYSEYDKCLTQKGSLRSHQLIHTGEKPY", "length": 544 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1M7A9-1", "protein_name": "Large ribosomal subunit protein uL6", "gene_name": "AABR07026048.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MANRLAHRPIQWRNFLSQDSLDQDTMRKKTILSNQTVDIPENVDITLKGRTAIVEGPRGTLRRDFNHINVELSLLGKKEKRLRVDKWWGNGKELATVRTICSHVQNVIKGVTLGFCYKMRSVYAHFPINVVIQENGSLVEIRNFLGEKYIRRVWMRTNVACSVSQAQKDELILEGNDIELVSNSAALIQQGTTVKNKDISKFLDGIYVSEKGTVQQADE", "length": 219 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1M9J5-1", "protein_name": "Uncharacterized protein", "gene_name": "Esp1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "ITFLPVTLFLIILLWPSMITEGRVLTQNQKELSISADHNKNHKSDLDKIEFQGQPNIQKAVEMTICASDKDQTLLEDQANANQDKQLYKDSHLLCGRSLDHIVK", "length": 104 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1QDL3-1", "protein_name": "Novel nacht domain containing protein", "gene_name": "LOC560232", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEDKHTPGDLDLSTGCSSVHQNRAEAEPSCVSMKSDVSMDPPTNFKSGNTGPAVSSRKRKRAEAEPSCVSMKSDASMDPPLKFKSKNTQPAVSVDRDDQSGDLLQDSLQPEHDELQRVKEQHKTTMKNKHERLFEGINHGETQTLLNRIYTQLYIIEGESEGVNEEHEVIQMEKRARTKPSQHTPVYCNDIFKASAGAGHEVKIKKEKAQIKTVLTKGIAGIGKTVSVQKFILDWAEGKANQDVDFMFVLPFRELNLIRDHQYSLHRLLLDFHPELEDLEPKIYEQCRVVFIFDGLDESRITLNFSDEEKVCAVTESSSVAVLMWSLLKGDLLPSALIWITSRPAAAHQIPSRYIKRLTEIQGFTEPQKEEYFRKRISDEHQASRIISHIRRARSLQIMCHIPVFCWISSTVLQKLLEEDVSAEIPQTLTEMYIHFLLIQINMRKQKYEERDPEKLLQSNRGVILKLAEVAFRQLMKGNVMFYEEDLIESGIDVTDALVYSGICTEIFKEESVIQQRKVYSFIHLSFQEFLAAFFVFYCHLTKKRELLELILGYSYDQYLQSSSEKSLYDLLSSAVDEAVRSSNGHLDLFLRFLLGVSLESNQRLFQDLLTHTEESSESIRRITQYIKDQIKSDDYFKRAAERFINLFLCLLEVKDQTLAREIQEFVKSDKHSEEELSPAHCSTISYMIEMSEEPLDEFELQKFNTSAEGRLRLTTAVRNCRRAL", "length": 725 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1QGM0-1", "protein_name": "Galectin", "gene_name": "lgals1l1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MPTVLIQNMAFKVGQTLTLTGVPKPESPEFTIDIGNSSEDIALHINPRFDAHGDQCIIVCNTFQNDCWCEEHRDENFPFVQGEEFQIKITFTNEEFLVTLPDGSEINFPNRQGSEKYKYMNFTGQARIQGIEIK", "length": 134 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1QMQ9-1", "protein_name": "Uncharacterized protein LOC541480", "gene_name": "si:ch1073-398c20.1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MADIKQESDDIRIAEVFTLKQEDPEEQTDLLPLRKEFQGLDNVKEEEALVEEHQDITPAEKRITCSETENTTQKASEKTGSRSSFTCEQCGRDFAKQGTLNNHMRIHTGEKSFTCQQCGKGFTQKRTLRNHIRFHIEAESLSCQQCGESFTQKQDLTDHMRVHTGEKSFVCDQCGKVFLRKDGLEKHLKNHHKEKPHVCPCGKSFTDKTKLEEHTKTHTGEKPHTCDKCDECFSGKYDLIRHMRFHSAETPYICQQCGKSFALKRVLMTHVKIHTRDRPFLCKQCGKCFYRKDNFNRHVRVHTGEKPYACSECGKSFSERFQFNEHSRTHSGVKRFSCEQCGRGFNRKTELKRHMRVHTGEKPYMCPQCGKTYAFKTGFDIHMLHHNAEMPYICPQCGERFSVKQRFDVHMKIHAGNSDK", "length": 420 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1R1Q6-1", "protein_name": "Uncharacterized protein LOC641576", "gene_name": "zgc:152710", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MVLIWTQFGVKHKNVKCKVRVIHGEEGSWSSEEVREEPEVSSPPPSPECVDYYSVLGVSNDSNEEEIRKAYKRLALRYHPDKNSDADAEDKFKQIAQAYDVLTDPEKRNIYDQQGLTKGGVAPTCNKTDPSHNSKADAHSWHMFFNFDLDSDDDLFNPFTRNPLPHLSRHHGNKGGLKPAGDAEVHDLSVSLEDILMGVTKRVKLTRLRQTDKHTLKPEERVFDVEVKKGWKEGTRITFPNEGHQMLGHAPNDLAFVIKEKKHAHFRRDGSHIVYTCTITLREALCGCTVNVPTLDGQMKPLPCSDVIKPSSVRRLIGEGLPRAKNPAQRGDLLVEFQVVFPDRIPPSSKEIIKHSLGQC", "length": 360 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1RA39-5", "protein_name": "[F-actin]-monooxygenase mical2b", "gene_name": "mical2b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MGETEEERTSQAGQLFENFIQATTCKGTLQAFSVLCRQLELNPSDHRGFYSSLKTAVTFWKAKGLWGKLDKRAGHKEYSKGRACADTRCLIIGGGPCGFRTAIELALLGAKVVVIEKRDTFSRNNVLHLWPYTIHDLRNLGAKKFYGKFCAGSIDHISIRQLQLMLLKIALIVGVEVHVNVEFVKLLEPPEDQSTDGQGWRAEIRPADNPVSDYEFDVIIGADGRRSTLDGFRRKEFRGKLAIAITANFVNRNTTAEAKVEEISGVAFIFNQKFFLELKEETGIDLENIVYYKDNTHYFVMTAKKQSLLDKGVIINDYIETERLLAFDNVNQEALLSYAREAADFGTNYQLPSLDYAINHYGQPDVAMFDFTCMYASENAALVREKSHRQLLVALVGDSLLEPFWPMGTGCARGFLAAFDTAWMIKGWAQGKEPLDLLSERESIYRLLPQTTAENISKNFEQYTIDPATRYPNLNSSCVRPHQVRHLFISGEQDLSSLERSGQTRRSVSISRRESEVRPGRLLLWCQNQTQDYRGVNVTDLNTSWRSGLALCALIHRQRPELIDFDSLNEADCAKNNQLAFDVAEREFGIQPVTTGKEMDAERGPDKLIMVLYLSKFYEMFHKSTQSVTGLPKEIDANNGDCSSKTANSLYNSINHARKRIPKLDKKLEESDVNRKRKKASSHHEELMSCQTAPPAGEREEQKENKVRSMATQLLARFEENAPSCALRRQSDSESDSDADRPVSLDLTENPRFARPKIEPTHPSTTPDKAKWQPSPYLRLLESNTRSETLHTEHYVESQSSHRLTEIQSECQYSSVSSAYKSSERRPRSPLIPFTPTLSPMMHCLQQLEEQVIQQRKREPLNRKSIKERAQKLSSLFTGNPAQPQTDESSPAVSPSSPPQTIPESSTLSCLLSPAPSLTHKQCSEASETHLKADKHTEIRRVERLDPSKQRTVGKVSSAIGVKAATLAILYETDHRPNNPITLSLTEARRCAESGLVSVRKEFSASLGGSDTCVFCQKRVYIMERLSAEGFFFHRECFRCHICGCSLRLGAHTFDSQQGTFYCKMHFSQRKTSTRHRRGEIQDGGIRSSSITISNHTSTDGTRGQPSGGEFDSSTQQDLQTLPDSKEIISVSEVKDSSKKADPADSAPACPDSPLQKVKRSTAKGEITNKNILWKKKIRSTLPLVLMKKFHRGKPEDKTEVLAEEDGNSDFEEIHESLSSKKPSNPSTDSNCLPTKDNSSTPLDEIPKIPLYRTHVLPEYPKPSSSSPEPIVTSISSDPISFSPKKKLTLSLSEKEKLLNWDLTNPGKSGAEEQQQQHVKPSISLQHDHPEPTHPQPEPAPPLFGFQQWANNLRKSFSKGSNPVVLRRNRPMKARPLSEGSFNVGAVFQDEERCGSLVDEGEARPRTESEIASLLEQVALGSKTSRGTKDDMASLPPRKLNFFSSLRIKRVEGAEQSRGEGQKDILSILSRFRNKASAQQQQQQKSNSSSEDEQEPKLTHSGALQKKKEKIAIRQTKSDELKRLHRAQVIQRQLEEVEEKQRSLEEKGVALEKVLRGENGDDGSTDEAALLQTWFKLVLEKNKLSRYESELMIFAQELELEDTQSRLQQDLRRRMATEDCEKSASELVEEQNILVEIMKVVEKRDKLVSLLEEQRLKEKAEDRDLESLILSRGYQFHWT", "length": 1679 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1RXL1-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100152495", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MFTICNDSHSDFILLGFSDKPYLEKILFWVVLIFYCLTIIGNLVIILVSLKDPKLHIPMYYFLSNLSLLDLCFTSSCVPQMLVNFGGPEKTISYIGCAIQLYVFLWLGATECVLLVVMAVDRYVAVCHPLQYTTIMHPKLCLELAILAWGTGLIQSLTQSPATLQLPFCSNRRLYDIVCEVPALIQVSSADTIYNEIQMSIASIILLVVPLVIILSSYGAITKALLRVKSTEGQKKAFGTCTSHLLVVFLFYGTVTAVYLQPKSHYAHEQGKFLTLFYTVITPTLNPLIYTLRNKEVKGALIRLGKKTWDDLCWTIA", "length": 317 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1RYD0-1", "protein_name": "Transcription elongation factor A like 3", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRQVKHLRSGSLPTPGLSVTSPSPTARPATPRTACLFPALCKTRKGEGTCPESLQDKKRRKNLNMEKLCKENEGKPESEGKPEDEVEPDNEGKSDEEEKPEVEGKSAHEGKLQNEGQPEDEGKPEDEGKQEKQGKSEDEGKPPGEGTMESQAKPESEPRAAEKRPAEDYVPRKAKRKTDRVTDDSPKDYEEDLQERHLGSEEMMREGGDLSRAQEELRKRQKMGGFHWMQRDVQDPFTPRGPRGVRGMRGGGRSQRGLHDIPYL", "length": 264 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1RYD7-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258723", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "LLVVVLVTYLLTLVGNTVIILIASIDPNLKTPMYFFLTHLSLVDICLTTSIVPQLLWNLRGPAKTITTLGCAVQLYVSLALGSTECVLLAVMAFDRHAAICKPLHYAAVMNPRLCQALAGVAWLSGVGNALIQSTVTLWLPRCGHRRLHHFFCEVPSMIKLACVDIHTNEVQLFIASLVLLLLPLALILTSYGHIVKAVTRIKSVQAWRKALGTCGSHVMVVSLFYGTITAVYIQPNSSYAHTSGKFISLIYTVLTPTLNPLIYTLRNKDVKGAMRRLFRRDLGS", "length": 285 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1S4M2-1", "protein_name": "Small ribosomal subunit protein uS13", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSLVILEKFQHILRVLNTTIDGWQKIAFATTAIKGVGRRYAHVVLRKADIDLTKRAGELTEDEVEHVITIMQNPGQYKIPDWFLNRQKDVKDGKYSQVLANGLDNKLHEDVERLKKIRAHRGLRHFWGLRVGGQHTKTTGRRGHTVGVSKKK", "length": 152 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1S6C0-1", "protein_name": "RING-type domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGNCLTPHTSEDLLVPASATHLGGRRRRARSRERRPRDQVPGWAPAAPLVQEEQVRVPQRISQIQCLPKGVYKRDGSQEKMEQEECAICTLDFVCGDPIRSLPCKHFYHLGCIDEWLTRSFTCPYCRGPADGPQPSSRDTP", "length": 141 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1S7I2-1", "protein_name": "Beta-defensin", "gene_name": "DEFB125", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MNLLLTFMICGLLTLVTKAGWNVERCWSYNIGHCRRRCLHLERYKHLCMNKRACCIPLSSDDPYTQWPLPPEDQTVGMKTPYFRPVSPGSELDDQITITITVDQESTGTEQDIEGTAISFQASTPIPENIEDTKFSDKANTLNLHKL", "length": 147 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1S7N4-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100152708", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDQTNSSVVTEFVLVGLTQSLGMQFLLFLLFSTFYVGIILGNLFIVFTVISDSHLHSPMYILLANLSLIDLGLSSTTVPRMISDLFSDCKTISFHNCMIQMFFIHVTGGVEMVLLIAIAYDRYTAICKPLHYLTIMNPQMCMLLVVAAWITGVTHAVFQFAFVINLPFCGPNNVGSFYCDFPRVIKLACIDNYGLEFVVTANSGFLSTGTFFLLVVSYIFILVTVRQHSSKDLSKAFFTLSTHITVVFLFFLPCMFLYVWPFPTKSLDTFLAIVDFAVTPVLNPAIYTLRNRDMKVEMRRLSRQVISSREMT", "length": 312 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1SBB9-1", "protein_name": "DNA-directed RNA polymerase RBP11-like dimerisation domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MHALPAFESFLLFKDEKITIHKDTKAPNACLFTIDKEDHTLGNVIKSQLLKDPQVLFAGCQVPHPWEHKIIVPVQTTPDYTPQEALLNVITDLISKLSLLEERLRVAIKDKQEGIECWTGRGPAWPGPALTLALLQAPCG", "length": 140 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1SBV4-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100154723", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MESENITVVTEFIFVGLTQSRNIQLLVFVLVFIFYLIILPGNFLIILTIRSDPGLTAPLYFFLGNLAFLDASYSFIVAPRMLVDFLSEKKVISYRGCITQLFFLHFLGGGEMLLLVVMALDRYIAICRPLHYSTVMNPRACYALSLAQWLGGFVHSIIQVALILHLPFCGPNRLDNFFCDVPQVIKLACTDTFVVELLMVFNSGLLTLICFLGLLASYAVILCRVRGSSSEGKTKAMSTCTTHIIVIFLMFGPGIFIYTRPFRAFPADKVVSLFHTVIFPLLNPVIYTLRNQEVKTSLKKLLINN", "length": 305 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1SJ79-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110259717", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEQNNGTKGTEFILLGFAGQHKSWPVLFIVFLVTYVVTLVGNIGMILLIKIEASLHTPMYFFLQNLEEKVDLCYATAITPKMLQNFVWTEHSISFIGCMVQLLTYGAFATSDCYILAAMAVDRYVAICNPLRYPTVMSQRVCIQLVIGSYFMGFLNASVNTSFTFQLNFCKSNKINHFFCDAPPILALSCSSIYFSIMLLAAFVGFNLTCTVSVVIFSYVFILAAILKISSAAGRKKAFSTCASHLTAVTLFYGTLSYMYLHHRTLESQEQEKLASVFYGIVIPMFNPLIYSLRNQDVREALKGVGKQCF", "length": 310 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1SLL7-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRRENQSSISKFLLLGLPIQPEHQGMFFVLFLVMYLTTVLGNLLIILLIRLDPRLHTPMYFFLSHLALTDVSFSSVTVPKMLMNMQTQDQSIPYAGCVTQTYFFIFLACIDNLLLAVMAYDRYVAICHPLHYAIIMREELCLCLLVLSWLLSCAYALTHTLLLAQLSFCADIIPHFFCDLDALLKLSCSDTSLSELVTFTAGAAVVIFPFIGILVSYGHIGLSILRVPSTKGICKALSTCGSHLSVVSLFYRTSMAVYLSSSGQFHDKDIIVSVMYTVVTPMLNPFIYSLRNRDMTLALGILFRNINIFSK", "length": 311 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1SMZ6-1", "protein_name": "10 kDa heat shock protein, mitochondrial", "gene_name": "HSPE1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAGQAFRKFLPLFDRVLVERSAAETVTKGGIMLPEKSQGKVLQATVVAVGSGSKGKGGEIQPVSVKVGDKVLLPEYGGTRVVLDDKDYFLFRDGDILGKYVD", "length": 102 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1SRB7-1", "protein_name": "Large ribosomal subunit protein eL31", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAVVQKSGEKKRGRSAINEVVTREHTTSIHKRIHGVGSKKRAPRALKEIRKFAMTEMGTPDVRNDTRLNKAVWAKGIRNVPRRICAPLSRKRNEDEDSPNKLYPLVTCVPVTTFKNLQTVNEDEN", "length": 125 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1SUB9-1", "protein_name": "Multifunctional fusion protein", "gene_name": "IL1B", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MATVPEPAKEVMANNGDNNNDLLFEADGPKEMKCRTQNLDLSPLGDGSIQLQISHQLCNESSRPMVSVIVAKEKPMNPSSQVVCDDDPKSIFSSVFEEEPIVLEKHANGFLCDATPVQSVDCKLQDKDEKALVLAGPHELKALHLLTGDLKREVVFCMSFVQGDDSDDKIPVTLGIKGKNLYLSCVMKDDTPTLQLEDVDPKSYPKRDMEKRFVFYKTEIKNRVEFESALYPNWYISTSQAEQKPVFLGNSKGRQDITDFTMEVLSP", "length": 267 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F2Z5L2-1", "protein_name": "Histone H2A", "gene_name": "H2AC18", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSGRGKQGGKARAKAKSRSSRAGLQFPVGRVHRLLRKGNYAERVGAGAPVYMAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGKVTIAQGGVLPNIQAVLLPKKTESHHKAKGK", "length": 130 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F4IWB9-1", "protein_name": "Cytochrome P450, family 705, subfamily A, polypeptide 28", "gene_name": "CYP705A28", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MIMGRSCSEKNGEAERVRGLVIESLALSPKIFLGMIFHKPLKKLGISLFQKDIKSVSPKFDELLEKFLVEHEEKMEEDHYKANDMMDLLLEAMEMRMQNVNLCIKRVSNTKARKPPILFRYGKYSNNSLLLQELLVAGTDTSALATQWTMAELINNPTILERLREEIESVVGNTRLIQETDLSNLPYLQSVVKEGLRLHPPASISVRMSQERCELGGFYIPEKTLLVVNTYAIMRDPNFWEDPEEFKPERFITSSRSEQEDEMREEVLKYIPFSAGRRGCPGSNLAYVSLGIAIGVMVQCFDWRIKGEKVNMSETAGTIMLAMAQPLKCTPVPRTLNLLPSSLHIPSS", "length": 348 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "F4J311-1", "protein_name": "Zinc finger (C2H2 type) family protein", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MDLDGVELLLDLREMVSQSGFEKSTTCSGVIALRSNLQSKSSHKCKICGKSFECYQALGGHQRIHRPIKEKLSKQEFSEVYPRKSKLQKRPESSSSCYECKVCGKIFGCYRGLGGHTKLHRSTKRELASTQDENSLLDSSEAKKIVSQPSSFKVSQEEKFLHCVELKQDFSEPLSHSGALPSTLRSKLQTKTQWKSSCHCKICGKSFVCSQGLGNHKRVHREISGKLACKRKYTEDYNPFSDSLKAKKIVKKPSSFEVSQEEKILHCVELKQDFGELLAHSGFDKSISCSKSIKVKKVARKNEKTEDSTSLFGVFVGEMSQRLHGCKTCGRKFGTLKGVYGHQRMHSGNHNRIEDENGLERIWGLKKKSRVCSVSAFDRFKGSSFMAEIEKHEVIEAALNLVMLCQGVYDFASISNLPLGDGFMDLELKPCPLRRKLQKKSRSSYKCSICEKSFVCSQALGSHQRLHRWKLVPKPEYIEDDSSLLDSSEAKKIVSKPSSFEHAQEEKILQCVEPKLEFHEQLAHSGFDKFDTCSKIRFSALPSPPEAKKIVSQPPSFEVSVDEKILYRAEPKLNFSEPLAHSCFDNSSSYRSIICGKSFVCSQALGGHQTLHRSIKGQLAGTEDGNSLSVTDSEASKIVAQPSSYKSQGI", "length": 650 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "F4JLV4-1", "protein_name": "Protease inhibitor/seed storage/lipid transfer protein (LTP) family protein", "gene_name": "DHYPRP1", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MASTTIILFLSFSIIPLLTIVRADNHSVYCPPPPPCICICNPGPPPPQPDPQPPTPPTFQPAPPANDQPPPPPQSTSPPPVATTPPALPPKPLPPPLSPPQTTPPPPPAITPPPPPAITPPLSPPPPAITPPPPLATTPPALPPKPLPPPLSPPQTTPPPPPAITPPLSPPLVGICSKNDTELKICAGILAISDGLLTTGRAEPCCSIIRNVSDLDAVTCFCKSVGAPRFSLSPNFGIFFKVCGRRIPQGFSCPGPSPTISPPPLPPQTLKPPPPQTTPPPPPAITPPLSPPLVGICSKNDTELKICAGILAISDGLLTTGRAEPCCSIVRNVSDLDAVTCFCKSVGARRFSLSPNFGIFFKVCGRRIPQGFSCP", "length": 375 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "F4K5R6-1", "protein_name": "Cell division cycle 20.6, cofactor of APC complex", "gene_name": "CDC20-6", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MMKSIALALCLTHHSPMVLSIVDYGDSQEKTIDSLWKKPHGSDLTWSGFSRVGVTEAYFAVPVDHFLTNPPSLRLSQTIYCRRGSSYVETEKVEEEDRDDFLKQVWFLTDNLVFFFVDIEEYIVIEQLGDTVYLWDASSCYTSKLVTIDDENGPVTSINWTQDGLDLAVGLDNSEVQVWDCVSNRHVRTLRGGHESRVGSLAWNNHILTTGGMDGKIVNNDVRIRSSIIGTYVGHTEEVCGLKWSESGKKLASGGNDNVVHIWDRSLASSNPTRQWLHRFEEHTAAVRALAWCPFQASLLATGGGVGDGKINFWNTHTGACLNSVETGSQVCSLLWSKSERELLSAHGFTQNQLTLWKYPSMVKMAELNGHTSRVLFMAQSPDGCTVASAAGDETLRLWNVFGEPPKTTKKAASKKYTEPFAHVNHIR", "length": 428 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "F5H284-1", "protein_name": "Peptidyl-prolyl cis-trans isomerase A-like 4D", "gene_name": "PPIAL4D", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVNSVVFFEITRDGKPLGRISIKLFADKIPKTAENFRALSTGEKGFRYKGSCFHRIIPGFMCQGGDFTRPNGTGDKSIYGEKFDDENLIRKHTGSGILSMANAGPNTNGSQFFICAAKTEWLDGKHVAFGKVKERVNIVEATEHFGYRNSKTSKKITIADCGQF", "length": 164 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "F6R3J9-1", "protein_name": "Spermatogenesis associated glutamate (E)-rich protein 1G", "gene_name": "Speer1g", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWRARRHTSSTAPDLSKKEFKKEKERLTTELHLLIQLRNEQRDHLIDFKESSNYNRTKPTQKKNPFYEQLRSTKNQVLSSVHKLEMGIIEAQENIQELNKWIDYFTNLHSQLLMEKNLKMSITQNKKNKEVEIDWALIEKYLVDLNLNGQTGADQQP", "length": 157 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F6X687-1", "protein_name": "Spermatogenesis associated glutamate (E)-rich protein 1A", "gene_name": "Speer1a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWRARRHTSSTAPDLSKKEFKKEKERLTTELHLLIQLRNEQRDHLIDFKQSSNYNRTKPTQKKNPFYEQLRSTKNQVLSSVHKLEMGIIEAQENIQELNKWIDYFTNLHSQLLMEKNLKMPVTQNQKNKEVEIDWALIEKYLVDLNLNGRTGADQQP", "length": 157 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F6YNI8-1", "protein_name": "Eukaryotic translation initiation factor 4C", "gene_name": "Eif1ad19", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPKNKGKGGKNRCRGKNENESEKRELVFKEYGQEYAQVTKMLGCGRLEAMCFDGVRRLCHIRGKLRKKVWINTSDIILVGLQDYQDNKADVILKYNLDEARSLKAYGELQEHAKINETDTFGPGDDDEIVFDDTGDDDEDIDDI", "length": 144 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F7AMQ8-1", "protein_name": "Exocrine gland secreted peptide 8", "gene_name": "Esp8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEKVSAMTSFPVMLFLIILLLPSICSEERTQADPTISADNKKNFKTVVDLTDCQCERNFIESLESTLPASNQDQTLFENMTNQHKLNLSKMLSVLSKCCTQKQQVDTVHFRRMPHRIQSTKQNNYKKQVLYPMQEFMNLTRDVLVSRYV", "length": 149 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F7C9P2-1", "protein_name": "F-box and WD-40 domain protein 25", "gene_name": "Fbxw25", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEIHLPSLPMLKILSYLDAYNLLQAAQVNKNWNALASSDVLWRKLCQRRWHYCDMVTLQLQGKETWKQFFIYRIWQEHAKTRAKPEDFTYKEIPVECGFYGYACYISGHGLTRNGQGKSVICMVSSKNTISTWDIHKSVITWVSPVQPASINLLTTLPDMHIAVTVDIQSTIKLWDCHNREALATNNLESPCKSLKAVISKDGPIVLVGDTLGNLYIFRIPDLHLISTVNVFPYGFDEIDCSPQKKWVLLSKNYPHILPKVFYMSSLLRTSEFSAPVSTILEFSLCQGAFWTPRREDRITLMSRSGFPQITKFETFDMKLEGIGNKVAVQGKLIASFFLPYYEESPNWIGVSDKDVIVCSTHFFLLLFTINGLHLQTFQYCPETIVRLCVDPVHVIVTCNNGSLDVYAWEERSLLLRKCYRLQNKRPLPLYGFINNLLCDDVSIVQLMRDGHGPYSLIAYALNICS", "length": 466 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F7ELE5-1", "protein_name": "NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial", "gene_name": "Ndufs7", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "RRTVVYTARARSQEKSGSEPLSLWFRFPLVSIWALDQNRNSLEDGPQRLSEGRGQDGGAGGSWLALCTDPGSAHRHSGSAAQSPPECGSHWEPEQSAVSKAGAGAVVPKPSHLPRSRAEYVVTKLDDLINWARRSSLWPMTFGLACCAVEMMHMAAPRYDMDRFGVVFRASPRQADVMIVAGTLTNKMAPALRKVYDQMPEPRYVVSMGSCANGGGYYHYSYSVVRGCDRIVPVDIYVPGCPPTAEALLYGILQLQRKIKREQKLKIWYRR", "length": 271 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F7F947-1", "protein_name": "Beta-defensin-like domain-containing protein", "gene_name": "Spag11b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDLSQRPPNVFRHVVDFLKKNQTHITQACSGNSGGRKASSSDLCGCALCLEAPSPHSQLSYKRACSSCPPTRGSSVPAVPSTAMKQRLLPSFVNLLLAALLLPGKAETWLRSWTQALSAVVTLGSSSASSINHLVTEPPSSPQDEFPAQGGNGSGLLHHRVKRFPPRTPPYHEPGPNYQIVNCKKNEGFCQKYCNFMETQVGYCSKKKEACCLHPF", "length": 216 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F7FNC4-1", "protein_name": "Interleukin 36, gamma", "gene_name": "Il36g", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSSKYPHSPCTASGKETPDLGQVSDVDQQVWIFRDQALVTVPRSHTVTPVTVTVLPCKYPESLEQGKGTPIYLGIQNPDKCLFCKEVNGHPTLLLKEEKILNLYHHPEPMKPFLFYHTLTGATSTFESVVFPGSFIASSKIGKPIFLTSKKGEHYNIHFSLDII", "length": 164 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F8VPX6-1", "protein_name": "Spermatogenesis associated glutamate (E)-rich protein 4A1", "gene_name": "Speer4a1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRANVNGRETREGRKDANLPPESNEGRRRWTWRMWMAHRQTTSSVPVTSKKQFEKEEKELIKKIQLTTKETNELRDRLIYVTEGSMNKRPYHRQTRHYKELKLKEKEIMTYLHNLEMENMEARENKQEFKKEKNFYRNLHTRILLEENLIKKKLAILQQESKEIHADWAIIQERLVELNLSCKDEQEKTSNLETQENQVSEAARELGLATAEEDSILQNELPCQEAPAEHHTQNPPSSSDESSSDESSYSTCPAWE", "length": 267 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F8VQM2-1", "protein_name": "C-C motif chemokine ligand 26", "gene_name": "Ccl26", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFFDLGLLVLLAIFLSVQLGVATCGSSIAMSCCPNFSYYVIPWSWVYSYKFTDKSCTSDGVIFFTKTGKQFCVQPGAKWVQRFISLVNTRNHL", "length": 93 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "G3GSG1-1", "protein_name": "Ferritin", "gene_name": "LOC100767129", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MGFLRKSHRRQRHRCPLRVSRATVAYPLVFMTPPIISPPSQVRQNYHFDCKTAVNNHVQLQLHNSSVYLAMAFYFDSEDVAQKNLASFFLNKSHECTAQAEMFLELQNQRGGRISLGSIREADRNNWLGGLQAMECALQLELSTNQSLVALHQLASSKSDAHLCSFLKNHFLTKQVEVLKEISGYVTKLRQMGSPDDGIAEYLFGKLTLDDNKGK", "length": 215 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3GWA3-1", "protein_name": "60S ribosomal protein L18a", "gene_name": "LOC100764432", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MKASGTLREYKVVGRCLLTPKCHTPPLYLMRIFALNHVVAKSRFWSQLKKMKSSGEIVHCGEVRPEVPLQVKNFAIWLHYDSRNGTYNMCREYWDLTVTQCYRDMGAQHCARTHCIHIMKVEEIASGKCQRPAVKQFHDSKIKFLLPHRVLRCQHKPHFTTKRLNTFF", "length": 168 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3H156-1", "protein_name": "Prefoldin subunit 4", "gene_name": "LOC100773780", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MVATMKKAAAEDVNVTFEDQQKINKFARDTSRITEQKEIEVKKNHLQNLEDTFNDIMLADGDCFMTQYLIRDVLISHSQEEAQEMLEEAKKTLQEEIDALESRVGAIQWVLANLKVQLYTKFGSNINLGVDES", "length": 133 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3H2T6-1", "protein_name": "Histone H4", "gene_name": "LOC100757199", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSGRGKGGKGLGKGGAKRHRKVLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG", "length": 103 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3H8X2-1", "protein_name": "1-acyl-sn-glycerol-3-phosphate acyltransferase gamma", "gene_name": "Agpat3", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MGLLAYLKTQFVVHLLIGFVFVVSGLVINFTQLCTLALWPISKQLYRRINCRLAYSLWSQLVMLLEWWSCTECTLFTDQATVDHFGKEHAVIILNHNFEIDFLCGWTMCERFGVLGSSKVLAKRELLCVPLIGWTWYFLEIVFCKRKWEEDRDIVKEGLQCLSDYPEYMWFLLYCEGTRFTETKHRISMEVAASKGLPPLKYHLLPRTKGFTTTVQCLRGTVAAIYDVTLNFRGSKNPSLLGILYGKKYEADMCVRRFPLEDIPADENDAAQWLHKLYQEKDALQEMYKQKGVFPGEPIKPARRPWTLLNFLCWATILLSPLISFVLGVFASGSPLLILTFLGFVGAASFGVRRLIGVTEIEKGSSYGNQELKKKE", "length": 376 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3HAB3-1", "protein_name": "40S ribosomal protein S15", "gene_name": "LOC100759804", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAEVEQKKKRTFRKFTYCGVDLDQLLDMSCEQLMQLCSTRQRLLLNCSLWRKQHSLLKSLRKAKKKVPPMEKPEVGKTHLRDMIILPEMAGSMVDVYNGKTFNQVEIKPKMIGHYLGEFSITYKPVKHGGPGVGATHSSRFIPLK", "length": 145 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3HDI6-1", "protein_name": "Lipid transferase CIDEB", "gene_name": "Cideb", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MEYLSALNPNGLLRSVSTMGSELGRRVWNSGPPPQRPFRVCDHKRTVRKGLTAATRQELLDKVLETLLLSGVLTLVLEEDGTAVESEDFFQMLEDDTCLMALERGQSWSPRSGMLSYGLGREKPKHSQDIARITFDVYKQNPRDLFGSLNVKATFYGLYSMSCDFQGVGPKKVLRELLRWTSSLLQGLGHMLLGISSTLRHVVEGAERWQWHKQNHLRS", "length": 219 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3HDS5-1", "protein_name": "Histone H3", "gene_name": "LOC100773314", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MARTKQTARKSTGGKAPRKQLATKAARKSAPATGGVKKPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVMALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGERA", "length": 136 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3HGI3-1", "protein_name": "PHD finger protein 6", "gene_name": "Phf6", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSSSIEQKKGSTRQRKCGFCKSNRDKECGQLLVSENQKVAAHHKCMLFSSALVSSHSDNESLGGFSIEDVQKEIKRGTKLMCSLCHCPGATIGCDVKTCHRTYHYHCALHDKAQIREKPSQGIYMVYCRKHKKTAHNSEADLEETFNEHELEPSSPKTKKKSRKGRPRKTNFKGLTEDSRSTSSHGTDEMESSSYRDRSPHRSSPNDTRPKCGFCHVGEEETEARGKLHIFNAKKAAAHYKCMLFSSGTVQLTTTSRAEFGDFDIKTVLQEIKRGKRMKCTLCSQPGATIGCEIKACVKTYHYHCGVQDKAKYIENMSRGIYKLYCKNHSGNDERDEEDEERESKSRGRLAIDQQLTQQQLNGN", "length": 364 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3HJW3-1", "protein_name": "Calcium homeostasis modulator protein 6-like", "gene_name": "LOC100774768", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MEKFKAVLDLQSKHRSALGYGLVTLLTAGGEKIFSEVVFQCPCSATWNLPYGLVFLLVPALALFLLGYALRTRTWRLLTGCCSWSASAQSSSGLQRVFVCAQISAAAALPPLTWVAVALLGGSFYQCAVSGSEAMARHLCKGRDPSCAAKLPQVPCKKQEAEMQDILSQLKAQSQVLGWILIAAIIILLLVVKSVTRCLSPVSYLQLKFWEIYLEKERQILQGEAMEHATQLAKENVRCFFDCTNPKDCSTPSSKAWQQISALYTFNPKNHFYSMLHKYVNRKDMSGSLRSVEGDAVVPVLGFVDASGMATTHGV", "length": 315 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3HQ40-1", "protein_name": "Eukaryotic peptide chain release factor GTP-binding subunit ERF3B", "gene_name": "LOC100767578", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MDLGSSSDSAPDCWDQVDMEVPGSAPSGDGFTSASTAAAEAAEAEAQRQHLSMAFSSQLNIHAKPFVPRVSAAEFVQSFLPGSAQPPAPTTSSSDETCTGAGDPQGKRLGWGAPVEPSKDGPLMSWEGSNSAVTMELSEPVVENGEVEMALEESWELKEVSEAKPGGSLGDSGPPEESGKEMMEEKEVIRKSKSMAIPSGAPKKEHVNVVFIGHVDAGKSTIGGQIMFLTGMVDRRTLEKYEREAKEKNRETWYLSWALDTNQEERDKGKTVEVGRAYFETEKKHFTILDAPGHKSFVPNMIGGASQADLAVLVISARKGEFETGFEKGGQTREHAMLAKTAGVKYLIVLINKMDDPTVDWSSERYEECKEKLVPFLKKVGFSPKKDIHFMPCSGLTGANIKEQSDFCPWYTGLPFIPYLDSLPNFNRSIDGPIRLPIVDKYKDMGTVVLGKLESGSIFKGQQLVMMPNKHNVEVLGIVSDDAETDFVAPGENLKIRLKGIEEEEILPGFILCEPSNLCHSGRTFDVQIVIIEHKSIICPGYNAVLHIHTCIEEVEITALISLVDKKSGEKSKTRPRFVKQDQVCIARLRTAGTICLETFKDFPQMGRFTLRDEGKTIAIGKVLKLVPEKD", "length": 631 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3HQN5-1", "protein_name": "Transcription factor 19 isoform X1", "gene_name": "Tcf19", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MLPCFQLLRIGGGRGGDLYTFHPPSRSGCTYRLGCRADLCDVALRPQQEPGLISGVHALLHAELQGDDWRVSLEDHSSQGTLVNNVRLPRGHRLELSDGDLLTFGPEGQAGTSSSEFYFMFQQVRVKPQDFAAITVPRSRGEAGTGFQPMVPSQGAPQRPLSTLSSAPKATLILNSIGSLSKLQPQPLTFSRGGGRPQSLAVPTQPGEVGASPPAPPTRNRRKSVHRVLAELDDENETSLSPLSVLMEPRKKLRLEKAALVSSGRD", "length": 266 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3HWQ5-1", "protein_name": "Zinc finger protein 219", "gene_name": "Znf219", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MEGSRPRILVGHLEPSPPAFDGELDLQHYSNGPGVSTGSPGMGAVGWSETRAGERRFPCPVCGKRFRFNSILALHLRAHPGAQAFQCPHCGHRAAQRALLRSHLRTHQPERPRSPAARLLLELEERALLREAQLGRARSSGGMQATPATEGLARPQVPSSSAFPCPFCKGKFRTSAERERHLHILHRPWKCSLCSFGSSQEEELLHHSLTAHGASERPLAATSTPEPQPPPQPEPRSALEPEPEPEPRPEPEHEANPAPTPAPPEEPPAPPEFRCQVCGQSFTQSWFLKGHMRKHKASFDHACPVCGRCFKEPWFLKNHMKVHTSKLGPLRAPGPGSTPARAPQPPDMSLLAYEPLGPALLLAPAPTPAERREPPSLLGYLSVRAGEVRPNGEGADPGAGRSYGGGFRPLPSALPNRARRHRTEEPEEEEEVVEAEEESWARGRSLGTLTSLHPHPGEGSGQSAPAVGAQARPTGTQEENGLLVGGARSEAGRGATGKDCPFCGKSFRSAHHLKVHLRVHTGERPYKCPHCDYAGTQSGSLKYHLQRHHREQRSSAGPGPPPEPPPPSPRGAASLQPQSGAKPTQASATWVEGTASTRPSSSGTGAGSRRKPASPGRTLRNGRGGEAEPLDLSLRAGPGGEAGSGGALHRCLFCPFATGAPELMALHLQVHHSRRARGRRQPRADTSPPYVRAPSGETPPSPPLEEEGSPGLSRSGEAGLGGQER", "length": 725 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3I071-1", "protein_name": "Large ribosomal subunit protein uL29", "gene_name": "LOC100753244", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAKIKARDLRGKKEELLKQLDDLKVELSQLRVAKVTGSAASKLSKIRVVQKSIVRVLTVINQTQKENLRKFYKGKKYKPLDLRPKKTRAMHRQLTKHEEKLKTKKQQRKERLYPLRKYAFKA", "length": 122 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3I1Z3-1", "protein_name": "DNA damage-inducible transcript 4 protein", "gene_name": "Ddit4", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MPSLWDRFSSSSSSSSSSSSGTPATDRPPRSAWGSAAREEGLDRCASLESSDCESLDSSNSGFGPEEDSSYLDGVSLPDFELLSDPEDEHLCANLMQLLQESLSQARLGSRRPARLLMPSQLVSQVGKELLRLAYSEPCGLRGALLDVCVEQGKSCHSVAQLALDPSLVPTFQLTLVLRLDSRLWPKIQGLLSSANSSLVPGYSQSLTLSTGFRVIKKKLYSSEQLLIEEC", "length": 231 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3IAH8-1", "protein_name": "Guanine nucleotide-binding protein subunit gamma", "gene_name": "LOC100755128", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MASNNTASIAQARKLVEQLKMEANIDRIKLSKAAADLMACCAAHAKEDPLLTPVPASENPFREKSFCTIL", "length": 70 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3IG76-1", "protein_name": "Olfactory receptor 7E24 isoform X2", "gene_name": "LOC100765597", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MYILALFGNLLIILTVSSDSHLHTPMYFFLSNLSMIDIGYISTTVPRVIVDIQTHCPVISYVGCLTQMSLIIIFACMDDMLLSVMAYDRFVAICHPLYYQVIMNPSSCGVLLLGSFLLSLVNLLLHYVAVLSFSNCEDIFEISNFFCGPSELFKLACFDTFTTNIVRYCAGALFGLLPISGIIFSYFKIVSSIMRSSSSSNGKWKTFSTCGSHLSIVCLFYGTALGMYFSSSLSLSPKTNAVASVMYTVVTPMLNPFIYSLRNKDIKTALRKILSRTF", "length": 278 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3IGD7-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100770882", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSGANSSSLTPEFFVLNGIPGLEDAHVWISLPFCFMYMIAVVGNCGLMYLIGHEEALHRPMYYFLTLLSFTDITLCTTTVPNTLCIFWFNLKKIGFKACLAQMFFVHTFTATESGMLMLMALDRYVAICYPLRYGTILTNPVIAKASLATFLRSVAFILPFTFLTKRLPYCRGNTIPHAYCDHMSVAKISCGNVKVNAIYGLLVALVVCAFDIFCITVSYTMILRAVMNLSSADARHKAFSTCTSHICAIVITYVPAFFNFFTHRFGGHTIPHHIHIIVANLYLLLPATMNPIVYGVKTKQIRESVIKFFSGDKSGITEIKGLQNK", "length": 326 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3INQ1-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100763177", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MFCNTSTPGHSTFLLTGFPGLEASHHWVSIPINLICVVSILGNSIILFLIRTDPALHEPMYIFLSMLAASDLGLCASTFPTMVRLFWLGIRELPFDLCAAQMFFIHAFTYVESGVLLAMAFDRFIAIRDPLHYATILPHSAVAKVGAAVLIRAILLNLPGPILLRRLLFPQVSVLSHCYCLHCDLVGLACSDTRINSLVGLVSILLSLGLDSSLIMLSYVLILRTVLSIASPGERLKALNTCVSHLCIVLIFYLPKLGLSVLHRVEKHSYPALAVLMANLHFLVPPFMNPVVYCIKSKQIRQGFLKRFQQKRVDVS", "length": 316 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3MYE2-1", "protein_name": "Large ribosomal subunit protein uL18", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGFVKVVKNKAYFKRYQVKFRRRQEGKTDYYARKRLVIQDKNKYNTPKYRMIICVTNRDIICQIAYARIEGDMIVCAAYAHELPKYGVKVGLTNYAVAYCTGLLLACRLLNRFGMDKIYEGQVEVTGDEYNVESIDGQPGALTCYLDAGLARTTTGNKFFGALKGAVDGGLSIPHSTKQFPGYDSESKEFSAEVHRKHIMGQNVADYMRYLTEDEDAYKKQFSQYIKNNVTPDMEEMYKKAHAAIRENPVYEKKPKKEVKKKRWNRPKMSLGQENDRVAQKKASFLRAQERAAES", "length": 295 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "G3MZM9-1", "protein_name": "Uncharacterized protein", "gene_name": "LOC107131211", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MNLFIYVLLLSIWTSSCLDRNESNGSATAVTTRAEFKQTKLQELRRRLLIIVIGTLITGYMVTCTCLLHYRCDSKEAHKAAKDKKEDITIKASRSSKISFTDSKSPTAGLGDPERQSVVSRIDKSSGPSSPRKVPSSAEKLVRPSSQKKPSKPSAPKKVLGSPPQEKLHRTRSPKKAHRQAHAHKLVSQVSPSYPEKAIKPTWPPSLQCRVKPTKTPLPYPKNQSFPEHSSADKLTKRQRYLKLKCPASAGRAEILSRPQPVKFCRCYKEKCLVCRAVSEPFITHVSEANKKHVPVPLFSRELKHFYKSYKKKQPKYNTLYGNMSDSDITTYNSDGESDREVIIMCNIKCKEDIYKNSPNN", "length": 361 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "G3UW31-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r176", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSQNKSVKTTVEVTLQILLLCQVGVGTVVNIFLFVHNLSPFLNGSQQRPIKVILANLALGNTLILLFAFPNNIRVFIPREFPTDLKCKLGYFIWLVARSTNMCSTCSLSTYQFVTLAPGTWGRVMLPGRAPNFLRYTCYSCWLFSVLNNAHIPMKVSGPQKTHNDSNSKSKWVCSTSGFSIGMRILSFAHDAVFISIIIWSSVSMVILLNRHHQRLQHIQSTNQKLRVHAETRASHTILLLVVTFVTCYLLDCICTVCNISFVDSRVWLRRVKEILSVSFPTFSPLLLIFRDPKDPCSLLFGC", "length": 304 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "G3UY92-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r158", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQLLLLCQFGVGTVAKVFLFVRNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMMAFAPKTPPTELKCKLESFSHLVARSTNLCSTCVLSFHQFVTLVPLNRGKGKLVLRASVTNMASYSSYSCWFFSVLSNIHIPIKVSGPQIKDNNTDSNRKLFCSTSGFSVGTVLLQFAYDATFMSIMVWASVSMVLLLHRHRQRMQHILTPNQDARGQAESRATRTILMLVVTFVSFYLLNFICIMLHALFMHSHFFVRLVSEILTAVFPSISPLLLIFRDPKDPCSVLFNC", "length": 307 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "G3V9M0-1", "protein_name": "Cystatin S like 1", "gene_name": "Cyssl1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MACLLYTQLFLLNTFILFLNLSLNPVLGQILAGIEKSIIEEEGALEALNFAVSEYNENNSDLYLSRVVEVKTVKTVQQQIEAGKTLLFDVILGKTACLKTQDDLSDCPLNEPTDLQEREFCSFEVHLPDWANAINLLSSICNRI", "length": 144 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3X693-1", "protein_name": "Ig-like domain-containing protein", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "RVFLPLLLLGVILPGGDNEDGPTSFHLIQISTFVNNTWAQNQGSGWLDDLQIHGWESDSGTAIFLKPWSKGNFSDDEVTELVDLFRAYFIGFTREVQDRVNEFQLEYPFVIQVTAGCELHSGEAIESSLRGALGGLDFVSIQNHSCVPAPDGSSRGQKFCALTTQYQGISDIIERLLSETCPRYLLGVLDAGKAELQRQVKPEAWLSSGPTPGPGRLLLVCHVSGFYPKPVRVMWMRGEQEQPGTQQGDLMPIGEAAGLNCRVKHSSLGDQDIILYWGHPTSIGLILVAIIVPSLILLICLAFGVLRFMGSHRIGHD", "length": 317 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "G3X9Q9-1", "protein_name": "Predicted gene 6526", "gene_name": "Gm6526", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLRRLFHRENGDQGETRPRQKESAIPSCKKRRMKSFWGRHMSAGKKSSQNCNITNHMKNMNKLEDMKFYIRKINAKRLELFPILDIDMNTDLNYRMNIEFTIIKSQHEKTMLDMEKMTQSISDTIETYKEFIEDKDSYSFTHSYLLKECNQLKEKVRMLLNENRKLLVEQADQEASYGEEKRFCDESSKNIHPKC", "length": 198 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "G5E8X8-1", "protein_name": "Oocyte maturation, alpha", "gene_name": "Omt2a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDTLVFTKVHLESWVYKGLRGQHDSILELLKENLHHYLCIEFDEGLNDTVVYIIGFKFFAMFAMFVIVSLACNLRTKRNRARAWARGLQSPVWWNRRYFI", "length": 100 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "H3BJ46-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r14", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSLSFMSSLLENILYFQAGLGVLANIFLLVFYIFIILGHRPKPMDLISCQLTFVHIMMFLAGENFWLANIFESLNVENDFKCKATFYTKRVMRGLSICITCLLSVFQAVMISHRNSLLAKFKHKLKIYMINALFYIWTFNLSLSSNLIFYVGGFTNMSQTKQLKVTKSCSLIPMNYIIRGLILTVISSRDMFLVGVMLTTSTYMVIILCRHQRQCKHLHSTSHLRASPEKRATQTILLLVVFFVIMYWVDFIISSTSILLWMYDPVIMIVQKFVVNAYPAITPFVQISSDTRVIRVVKNWHS", "length": 303 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "H3BJ88-1", "protein_name": "Vomeronasal 2, receptor 3", "gene_name": "Vmn2r3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKMAIRKKCLILELTVFLCVELYAQYEDQNMTCRLMRKFNLTGYVEAENHHFVIGGQFPVHYRTIPTSDSDEEPESPMCEGFNFRGFRWMKTMIHTIKEINERKDILPEHTLGYQIFDNCFSTTKAMESSMVFLTGQDEYKPKWRNSTGKYLIGIIGAGGSTMSLAGARILLLNDVVQVGYASSSSILTEYLNVYRTIPSDKFQTEAIVNLIRHFGWVWIGAIASDDDYGKHGVKSFRKILETNNLCIAFSETIPKVYSNEKMQIAIDAVKSSTAKVIVLYATDFDLSPFVLEVIHHNIAHRTWIATEAWITSALIAKPEYFPYFGGTIGFAIPRSVIPGLKEFLYDVHPSKDPNDVLTIEFWQTAFNCTWPNSSVPYNVDHRVNMTGKEDRLYDMSDHLCTGKEKLKDLKNTYLDTSQLRITNNVRQAVYLMAYGLDRLIRVLIKEYREYLLHPKILAFMSYKLFEYIRKVKFTTHDGRKIELNVHGDIENGYYDILNWQMDNTGDIAIVKVGEYKFTRSKYELVLPKNSTLFWNTESSRLPDSVCTKVCPPGTRKGFITGQPVCCFDCIPCEDGYVSEKPGQRLCNPCSEDDWSNAEKNKCVPKHVEFLAYEEALGFTLVILSIFGALVVLAVTVVYVIHRHTPLVKANDRELSFLIQISLVITVLSTMLFIGKPCNWSCMARQVTLALGFCLCLSSILGKTISLFFAYRISISKTQLISMHPSFRKLIVLLCVFGEIGVCASYLVLKPPSMFKNIERQNVKIIFECNEGSVEFLCSIFGFDVLLALLCFVTTFMARQLPDNYYEGKCITFGMLFFFIVWISFVPAYLSTKGKFKVAVEIFAILASSYGLLGCLFLPKCFIILLRPKRNTDETVGGRVPTVDRSIQLTSASVSSELNSTMVSTVLDE", "length": 909 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "H3BKT1-1", "protein_name": "piRNA-mediated silencing protein C19orf84 homolog", "gene_name": "Gm52993", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDELEDGALSNGDNLSLPSAGTESWPTSATPGLPPSLLSTLDPTHLGLPEQLASVTVPIRLDTLSYLLHSALLGTYNLQQSLPPCSCTAQPSHIWPDTVRRPPRRSGQARGGWEVRRRPSRGWGRGRGRGRVWAQSQRGPERAEERERNMAGEPGAGPSTPPVTPPSQDGQKEAGGLSEDWEADY", "length": 185 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "H3BLP0-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r25", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSLTNILYFQAGLGILANTFLLCFYTFTILCHRSKPMDLTSCQLTLAHILFLLAGGDNWLAVILESLNIENDFKCKAIFYTNRVMRGFSICITCLLSVFQAVTISPHTSLLAKFKHKLKTYIIYAVFYIWFYNFLVCSHLLVYVGGFNNVSETNQMRVTESCSLFLMNYIISGLIFTVTTFRDVFLVGVMLITNAYIVIILFRHQRHCKHLHSIRHLRVSPEKRATQTILLLMVFFVVMYWVEIIISSTSLLLWMYDPGFLTVQKLIVTVYPTITPLVQISSDKRVINVLKNLQSKCQQIF", "length": 302 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "I3ITL1-1", "protein_name": "Gap junction protein", "gene_name": "gjc4a.2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSWDFLTHLLDEISNHSTFVGKIWLTLLIVFRIVLTVVGGETIYDDEQSEFVCNTLQPGCKNVCYDAFAPLSHVRFWVFQIIMISTPSVMYLGFAMHKIARMADNEYQPRKHKMLSTVHQRMNRDYDMVDEMTEEVPMIPEEIEPSEKDNKSAASTKTTAASDAAVKHDGRRRIKRDGLMKVYVLQLISRVAFEIAFLFGQCILYGFEVSPSYICTRSPCPHTVDCFVSRPTEKTIFLLIMYVVSVLCLALTVLEILHLGIGGLRDSFRSRANRRLPVHRPSTSTICHRLSSAPPGYQAVQKKYSSGKLKAEFLSDSGRESLADDNTTRDLDRLRRHLKIAQQHLDQAYHTEEVGASHNSGPDSKSIAAEQNRLNQAQGGFGSTEEKVFKEAHA", "length": 394 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "I3L8A5-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "FPSRQERTMRRENQSSISEFLLLGLPIPPEQQGVFFALFLGMYLTTMLGNLLIILLIRLDPRLHTPMYFFLSHLALTDISFSSVTVPKMLMNMQTQDQSIPYAGCVTQMYFFMFFACLDNFLLTSMAYDRYVAICHPLRYTSIMRGGLCTLLVTVSWILSCANALCHTLLLAQLSICAENTIPNFFCDLGALLKLSCSDTSFNDLAIFIAGVATIMLPLLCILVSYGHIGATILKIPSTKGICKALSTCGSHLSVVFLYYGTIIGLYLVPSSSTSSHKDIVASVMYTVVTPLLNPFIYTLRNRDMKGALEKLFHKAPVLS", "length": 320 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "I3L8Z8-1", "protein_name": "LRRC37A/B like protein 1 C-terminal domain-containing protein", "gene_name": "LOC100514982", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MMTLELEKLILPSHMACCLCQFKSNIEVVCKTVKLHCDRCLKNSTRCDKETSLGDVEGSFMKVLQARKKNTSTELMIEPERPSSDKSGVSLSSFMNEQLDFSDESDVISALNYILPYFSEGNLEDVESTLLPFIQLLFSNVAEADIPPGHLKTHTGNPPVNPESGTSGYTNKLRQLRFLENLLDAEIQEKIDEVMKKEKTAMLIYSNILSPKLRRQILRKKLETARTQAESLEEIESVDKRPLKVNRVLKGPRGIKKRHFRAMRRQSIRRKETAQPFVETTTKGSKLGGPSARELEQLWVVQRPRKRVADSLQKEPSFGREHKAEVSSFLKQYSRGRPAASIHPKAPATVKKTSEDLSDTLFVLVDANARVKNRKASETISYPRKIDSFHPSHSPVLHRTPEPQNRQAFRDKGSSYRLLLALRPLSSAVRSLINSPSQEASSPSGELTLQEQPSPESFSPSEPSTEHIISEKDTPQVVFEELPTSGTTTLSGPIPGPTAQGTLPTEYSATTADNVMPTGQHTSAIQWEHHNVGTDVASTPTSFISPGVSSPGSQFEAQLNQQLQSLIPNNDVRRLISHVIRTLKMDCSEPQVQLACAKLISRTGLLMKLLSEQQEAKASKAEWDTDQWKTENYINENTEAQGEQKESSELTKDVPGYGYNNKLILAISVAVVLMLLIVILCLIEVYSRRRTLREGKVGRRRGFFGFLLRKRRSGESESEGFFWRRRPLWLRDTYRPLSATRKKNMAEKLHDKESSDEEEIFHKGAGEVSEAPADVILTIESDVEDLGEETDTAPEGPPE", "length": 799 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "I3LBH4-1", "protein_name": "Large ribosomal subunit protein uL11", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MPPKFNPNEIKAMYLRCTSGEISAKSALAPKIGPLGLSPKEVGDDIAKAAGDWKGLRITVKPTIQNRQAQMEVVPSASALIIKAPKELPRDRKKQKNIKHSGNITFDEIVNIARQMRRCSLARELSGTIKEILGTAQSVGCNVNGRRPHDIIDDISSGAVECQAS", "length": 165 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "I3LC12-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MFGANLTIFHPTVFILLGMPGLEIYHTWLSIPFCLMSIVAVLGIGALILVVLSESTLHEPMHVFLSMLAGTDNLLSTTTVPKALAIFWFHAGEIAFDACITQMFFIHVAFVAELGILLAMAFDRYVAICALLRYTAVLTPSTIVKLTLAIWGWGIGTIFPIIFLLKRLPYCRTNIIPHSYCEHIGVARLACADITVNIWYGFSVPMASVLVDVAFIAVSYTLILQAVFRLPSQDAQHKALNTCGSHIGVILLFFIPSFFTFLTHRFGKNIPHHIHILLANLYVLIPPMLNPIIYGAKTKQIRDSLAHMLSRVGMS", "length": 315 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "I3LEQ2-1", "protein_name": "All-trans retinoic acid induced differentiation factor", "gene_name": "ATRAID", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MARPGFRSPSSLVPRAAALLLVLSVPRALALPEICIQCPGDVQNLSEVALYCKQTPELMLQGRCCLNGKGTILGLDLQNCSLKDPGPDFAQAHTAVIIDLQANPFEGDWANTFRGFTQLQTLILPQGVNCPGGINAWDVVTFYITNQTCQGQRTFATALGTQKRVLRMDLVLLMVLVSCSVFVLMASMATSVCARAHSHCSCSSVFWDPQHYPFPSCFGGLNAEKPRLHEPQRSSY", "length": 236 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "J3QM75-1", "protein_name": "Secretoglobin, family 2B, member 19", "gene_name": "Scgb2b19", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKGTLLLLGLLITGELSFQTTEACVPFFEGYASVVSGSRVWLYHELQSFDATAEEKVALEKIQGCYREERLRNILLEPKIMEAMVASPECRSYYSLNNFRSILDFISNLLGE", "length": 112 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QMG8-1", "protein_name": "T cell receptor alpha variable 13N-3", "gene_name": "Trav13n-3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKRLLCSLLGLLCTQVCWVKGQQVQQSPPASLVLQEGENAELQCTYSTTLNSMQWFYQRPGGRLVSLLYSPSWAEQRGGRLTSSAASNESRSSLHISSSQITDSGTYLCAME", "length": 112 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QML3-1", "protein_name": "BTB domain containing 35, family member 29", "gene_name": "Btbd35f29", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHQGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKKVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIIWDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYNEEQIVMKLDSDALTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QMQ9-1", "protein_name": "Predicted gene, 20873", "gene_name": "Gm20873", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSLMKKRRRESSSNTLRNIVGRRISHSWKEGNEPVTQWKAIVLDQLPTNPSLYLVKYDGIDSIYGLELYSDDRILNLKVLPPIVVFPQVRDAHLARALVGRAVQHKFEGKDGSEVNWRGVVLAQVPIMKDLFYITYKKDPGLYAYQLLDDYKEGNLHMIPDTPPAEERSGDDSDVLIGNWVEYTRKDGSKKFGKVVYQVLANLSVYFIKFHGDIHIYVYTMVPKILEVEKS", "length": 232 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QMS5-1", "protein_name": "BTB domain containing 35, family member 2", "gene_name": "Btbd35f2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLSCRDSSLLEPQPEDIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKKVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QMW5-1", "protein_name": "Eukaryotic translation initiation factor 4C", "gene_name": "Eif1ad17", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPKNKGKGGKNRRRGKNENESEKRELVFKEYGQEYAQVTKMLGCGWLEAMCFDGVRRLCHIRGKLRKKVWINTSDIILIGLRDYQDNKADIILKYSPDEARSLKAYGELPEHAKINEMDTFGAGDDDEIMFDDIGEDDEDIDDI", "length": 144 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QMW9-1", "protein_name": "BTB domain containing 35, family member 6", "gene_name": "Btbd35f6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLSCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYRDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLQTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QN64-1", "protein_name": "BTB domain containing 35, family member 22", "gene_name": "Btbd35f22", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDMKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYIDNISFLESEEGLIFQPVFKKLRFQHIIWDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYNEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QNQ5-1", "protein_name": "BTB domain containing 35, family member 24", "gene_name": "Btbd35f24", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEGIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKDTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIIYDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QP08-1", "protein_name": "Histone H2A", "gene_name": "H2al1k", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAKKMQRRRRQKRTRSQRGELPLSLVDRFLREEFHSSRLSSSALSFLTSVLEYLTSNILELAGEVAHTTGRKRIAPEDVRLVVQNNEQLRQLFKPGGTSVNEDDN", "length": 105 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QP87-1", "protein_name": "Eukaryotic translation initiation factor 4C", "gene_name": "Eif1ad14", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPKNKGKGGKNRRRGKNENESEKRELVFKEYGQEYAQVTKMLGCGRLEAMCFDGVRRLCNIRGKLRKKVWINTSDIILIGLRDYQDNKADVILKYNQDEARSLKAYGELPEHAKINETDTFGAGDDDEIVFDDIGDEDEDIDDI", "length": 144 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QP96-1", "protein_name": "PRAME like 3C", "gene_name": "Pramel3b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MMDTKDPPTLLDLATQSLLSNEHAAIQALEEIPRELFVPLFTAAFTGRHKNILTAIVKAWPFACLHIGALSVQEPERELLKALIESLQFLPALNSATRSPKLRILDLRQDAGCKTVCPDISTNSTICFRSCAHSEHSIFKIEGQESLSSSKSEAQPSRLPMELIVDISLDGTLRERNFFALLQNKVEQSLGSLHLCCRDLQINNLCECRHALSHLDLKCVDHLAVDESPLTEVTKLLSHTIQLDSLSLSKIACRSLNGRTFRNFITQLSRMNHLKELSLSSFCLTDHLETVLRVLSADLEFLYLPFCGLSYSDFKFLSECSQVSHLKLLNVNNNPIYWEDCEPFYYLLQNVSSTLQHLKICYCFLTDSTISVLIPALTRCSQLRVLHFYSNQITMGMLMRILELLTPLKELKHVIYPIPVHCYGRWHFQGSLDRQKVEDVQRQLNLMLQEAERSDMNWITYSD", "length": 463 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QPI8-1", "protein_name": "Eukaryotic translation initiation factor 4C", "gene_name": "Eif1ad16", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPKNKGKGGKNRRRGKNENESEKRELVFKEYGQEYAQVTKMLGCGWLEAMCFDGVRRLCHIRGKLTKKVWINTSDIILIGLRDYQDNKADVILKYNPDEARSLKAYGELPEHAKINEMDTFGAGDDDQIVFDDIGEDDEDIDDI", "length": 144 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QQ02-1", "protein_name": "Eukaryotic translation initiation factor 4C", "gene_name": "Eif1ad11", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPKNKGKGGKNRRRGKNENESEKRELVFKEYGQEYAQVTKMLGCGRLESMCFDGVRRLCHIRGKLRKKVWINTSDIILIGLRDYQDNKADVILKYNPDEARSLKAYGELPEHAKINEMDTFGPGDDDEIVFDDIGDDDEDIDDI", "length": 144 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7GP63-1", "protein_name": "Large ribosomal subunit protein eL39", "gene_name": "RPL39", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSSHKTFRIKRFLAKKQKQNRPIPQWIRMKTGNKIRYNSKRRHWRRTKLGL", "length": 51 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "K7N5V5-1", "protein_name": "Predicted gene 5862", "gene_name": "Gm5862", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRVNVDGRETREGRKDADLPSERNEGRRRWTWRMCMAHRQTTSPVPVKSKKQFEKEEKELIKKIQLTTEETNELRDRLIYVTEGSMNKRPYHRQTRHYKELKLKEKEIMTYLHDLEMKNMEARENNQELKKEKNFYRNLHTRILLEENLIKKKLVILQQESKEVHADWATIHQSLVELNLSGKDEQEKTSNLETQEHQVSEAARELGLATAEEDSILQNELPCQEAPAEHHPQHPPSSSDESSSDESSYSTCPEWE", "length": 267 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N660-1", "protein_name": "Predicted gene 10220", "gene_name": "Gm10220", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRVNVDGRETREGRKDADLPSERNEGRRRWTWRMCMAHRQTTSPVPVKSKKQFEKEEKELIKKIQLTTEETNELRDRLIYVTEGSMNKRPYHRQTRHYKELKLKEKEIMTYLHDLEMKNMEARENNQELKKEKNFYRNLHTRILLGENLIKKKLAILQQESKEIHADWAIIQQRLVELNLSGKDEQEKTSNLEAQENQVSEAARKLGLATAEEDSILQNELPCQEAPAEHHPQHPPSSSDESSSDESSYSTCPSWE", "length": 267 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6B6-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r168", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSQNGAMKTTEEVALQIVLLCQFGIGTMANILLFVHNFSPLLTGCQLRPKEVICANMAVSSILILFMTVFPNNVFVAQRNLLNDLQCKLEYFVYMVARSTNLCSTCVLSTYQFVTLVPGNFSELMVRGRSPKVISYSCCSCWLFGILYNVYIPMKVSGPQNRHNKTSTKSKWVCFTSGFSVGIVFLSFAHDAIFISIMVWASVSMVRLLYRHYQRLQYIFPPHQGNRGYAEIRAAHSIVLLVVTFVSFYLLHCICFILHIVFVDSNLWLRHIGEVLTSSFPTISPLLLIFRDPSYPCSLIFNYKKPVI", "length": 309 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6B7-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Gm10670", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSVRGKSLKTTEEVALQIILLCQFGVGTMANDFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTVFPNNMMAFAPRNPPTELKCKLKFFSHLVTRSTNLCSTCVLSMHQFVTLVPISRGKLLLRASVPNLVSYSCYGCWFFSVLSNIHIPIKVTGPQITDNNTDSKSKFFCSTSGFTVRIVFLQFSHDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQNPRGQAESRATNTILMLVVTFVSFYLLNFICIIFHTFFIHYNLFIRLLGEILAAGFPTISPLLLIFRDPKNPCLELFHCFKPESLQNLKHRRQLH", "length": 321 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6G6-1", "protein_name": "Predicted gene 16440", "gene_name": "Gm16440", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLRRLCQKENGDEGEIRTTEKEEGILSHEKGRRKSFWRRHRSARNTSTQNSKITKQRSKINELEELKLDMRKISNDMEEMGGILELYIYEDLNYRMNTEFNIIKSQHEKTMLDMNEMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLSEKVRILLNENRKLLVEQAGTQLSHEEEKRFCEEASKNICASSAKEQQCVNSSRNRNMAQTTT", "length": 218 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6J5-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r127", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSDHGKSVKTTEEVALQLLLLCQFGVGTLANVFLFVHNFSPVLTGSKQRPRQVILSHMAMANALTLFLTIFPNNMIAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIHQFVTLVLVNRGKLILRASVPNFVSYSCYSCWFFSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGIVFLQFAYDATFMSIMVWTSVSMILLLHRHRQRMQHILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNFICIIFHTLLMHSHLFIRLVSEVLTAVFPSICPLLLIFRDPKDPCSVLFNC", "length": 305 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6P1-1", "protein_name": "Reproductive homeobox 2H", "gene_name": "Rhox2h", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEKRSINYLLDVGPEEDEENANGVKTLMVLLAGEGRNEGESGRGLPGSGVSAAEGYRAGELSAGGPAAPVAGLMDNSNQEDLSATGCAQEKETQPEEPVPDSMGDLENVKPMSGPWSTVNPVRVLVPKFRHLWRHNFNVLQLQELESIFQCNHYISTTEENRLARSMGVSEATVQEWFLKRREKYRSYKRL", "length": 191 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6T9-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r175", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLLQNKSVKTTEEVALQVLLLCQVGFGTAVNIFLIVHNLSPILNGSQQRPIKVILANLAVGNTLILLFAFPNNMTLFVPKDPPTDLKCKLGYFIWLVARSTNMCSTCFLSTYQLVTLAPGTWGRVMLRGRAPKFVRYICYSCWLFSVLNNAHIPMKVNGPQKTHNDTNTKNKWVCSTTGFSIGMRILSFAHDAVFISIIIWSSVSMVILLNRHHQRLQHIQSTNQKLRVHAETRASHTILLLVVTFVTCYLLDCICTVCNISFLDSRVWLRRVKQILDVSFPTFSPLLLIFRDPKDPCSLLFCC", "length": 304 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6U2-1", "protein_name": "Predicted gene 3542", "gene_name": "Gm3542", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSRLLRLCQKENGDEGETRPKKKEEGILSHEKGRRKSFWRRHRSARNTSTQNSNITNQISNINKVEELKLHIRKTSNERKEMCGILNVYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLNEKVRILLNENRKLLVEQAGTQVSCEEERGSLRRPARTSVPQVQRNSSFPKCETVQQKLEHGTDHDMISLKEKCWWKRTGCAQEIHHCCLSSLITMAVMGCMLLLYFGFLGMNRP", "length": 270 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6W5-1", "protein_name": "Predicted gene 17019", "gene_name": "Gm17019", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRANVDGRDTREGRKDADLPSERNEGRRRWTWRMWMALRQTSSPVPVISKKQFEKEEKKLIKEIQLTTEETNELRDRLIYVTEGSMNKRPYHRQNPLYEKLKLKEKEIMTFLHNLEMENMEAQENKQELKKETHFYRNLHSRLLMEENLIKKKSMTLQQESKEVQADWAIIHQRLVELNLSVKDEQENSNLETPEYQVSEAARELGLATAEEDSILQNELPGQEAPAEHHLQHPQSSSDESSSI", "length": 255 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6W9-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r170", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLLQNKSVKTTEEVALQVLLLCQVGVGTAVNIFLIVHNLSPNLNGSQQRPIKVILANLAVGNTLILLFAFPNNMTLFVPKDPPTDLKCKLGYFIWLVARSTNMCSTCSLSTYQLVTLAPGTWGRVMLRGRAPKFVRYICYSCWLFSVLNNAHIPMKVSGPQKTHNDTNTKNKWVCSTTGFSIGMRILSFAHDAVFISIIIWSSVSMVILLNRHHHRLQHIQSTNQKLRVHAESRASHTILMLVVTFVTCYHLDCICTFCNISFLDSQLWLRRVKQILDASFPTFSPLLLIFRDPKDPCSLLFCC", "length": 304 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6X3-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r94", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSDHGKSVKTTEEVALQLLLLCQFGVGTLANVFLFVHNFSPVLTGSKQRPRQVILSHMAMANALTLFLTIFPNNMIAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIHQFVTLVLVNRGKLILRASVPKFVSYSCYSCWFFSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGIVFLQFAYDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQDARGQAETRATHTILMLVVIFVSFYLLNFICIIFHTLLMHSHLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFNC", "length": 305 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6X7-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r103", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSDHGKSVKTTEEVALQLLLLCQFGVGTLANVFLFVHNFYPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMIAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIYQFVTLVLVNRGKLILRASVPNFVSYSCYSCWFFSVLSNIHISIKVTGPQITDNNTDSKSNLFCSTSGFIVGIVSLQFAYDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQYRRGQAETRATRTILMLVVTFVSFYLLNFICIIFHTLLMHSHLFIRLVSEVLAAVFPSISPLLLIFRGPKDPCSVLFNC", "length": 305 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6Y3-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r115", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSDHGKSVKTTEEVALQLLLLCQFGVGTLANVFLFVHNFSPVLTGSKQRPRQVILSHMAMANALTLFLTIFPNNMIAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIHQFVTLVLVNRGKLILRASVPKFVSYSCYSCWFFSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGIVFLQFAYDATFMSIMVWTSVSIILLLHRHRQRMQHILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNCICIIFHAFYIHSRLFIRLVSEVLAAVFPSICLHNGVLLSY", "length": 295 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6Z0-1", "protein_name": "Predicted gene 17026", "gene_name": "Gm17026", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "XRSSWVPKQACCPCSSGYFRERIEYTQTPDQGRRRPAAHHGGKGQETTGHGEGSAGAASPQAPTINDQEKRHERLEKLKRELQNIKNARDELQGILANYTNKDLNDRINFETFMLQMQHDQVMTDLKRMPQDISEALYKCKQLTKENQFYCFRNCHLLIESNLIQHKVRMLRKENRQLLREQIALEECNIETKILCKEGSQKIKDHYTKQQQI", "length": 213 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N701-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r159", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSDHGKSVKTTEEVALQLLLLCQFGVGTLANVFLFVHNFYPVLTGSKQRPRQVILSHMSVANALTLFLTIFPNNMIAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIHQFVTLVLVNRGKLILRASVPNLVSYSCYGCWFFSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGIVFLQFAYDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQNTRGQAESKATRTILMLVFTFVSFYLLNFICIIFHTLLMHSHFFIRLVSEVLAAVFPSISPFLLIFRDPKDPCSVLFNC", "length": 305 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N708-1", "protein_name": "Predicted gene 10128", "gene_name": "Gm10340", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLLRLFQKENGDEGETRPTEKEEGILSHEKGRRKWLWRRHRSARNTSTQNSKMTKKRSKRNELEELKLDMRKISNDMEEMCGILNLYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLHENVRILLNENRRLLVEQAGHKCPVGKKRGSLRRPARTSVSQVPRNTSVI", "length": 205 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N731-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r57", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEVLALNILLLCHVVVGTVGNILLFVHNFSPNLTDSRLRPIQVILINLAVANAFMLLFSTYSYDLIDFVPRKPPTDLKCKLAYFFHMVARGTIMCSTCVLSTYQFVTLVPGNWARVMFREISPKVVSYSCFSCWLFSVLNNAYIPMNVSGPQKSHNDSDSKDNWICSISGVSVDMNFLRFSHDIIFLGIMAWTSVSMVIHLNRHHQRMNHIHKVNQNNRGHAETRAAHTILMLVVTFVSLYILNCIIILFHITFVESRLSLRHVTKLLSLSFPTISPLLLIFREPRGHCSLLFSVGLEIHVTGGVITEEQ", "length": 310 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N744-1", "protein_name": "Predicted gene 8104", "gene_name": "Gm8104", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLRRLFHRENGNQGETRPRQKESAIPSCKNRRMKSFWGRHMSAGKTSSQNCNITNHMKNMNKLDDMKFYIRKINAERLELFRILDIDMNTDLNYRMNIDFTIIKSQHEKTMLDMEKMTQSISDTIEKYKEFIEDKDSYSFTHTYLLKECNQLKEKVRMLLNENRKLLVEQADQETSYGEEKRFCDETSKNIHPKC", "length": 198 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N751-1", "protein_name": "Predicted gene 3696", "gene_name": "Gm3696", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLLRLFQKENGDEGETRPKKKEEGILSHEKGRRKWLWRRHRSARNTSTQNSKMTKKRSKRNELEELKLDMRKISNDMEEMCGILNLYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLNENVRILLNENRRLLVEQAGHKCPVGKKRGSLRRPQEHLCPKCQGTAV", "length": 203 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N757-1", "protein_name": "Predicted gene 3667", "gene_name": "Gm3667", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLLRLFQKENGDEGETRPTEKEEGILSHEKGRRKSFWRRHRSARNTSTQNSKMTKKRSKINELEELKLDMRKISNDMEEMCGILNLYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLNEKVRILLNENRRLLVEQAGHKCPVGKKRGSLRKPARTSVSQVPRNSSVK", "length": 205 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K9J7F4-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r260", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGNSLKTTEEVALQILLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMMAFAPKTPPTELKCKLESFSHLVVRSTNLCSTCVLSVHQFVTLVPLNRGKGKLVLRASVTNMASYSSCSCWFFSVLSNIHIPIKFSGPQITDNNTDSKRKLFCSTSGFSVGIVFLQFAYDATFMSIMVWTSVSMVLLLRRHRQRMQHILTPNQNPRGQAESKATHTILMLVFTFVSFYLLNCICIIVHALFMHSHFFVRLVSEILTAIFPSISPLLLIFRDPKDPCSVLFNC", "length": 307 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K9J7G0-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r163", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQILLLCQFGVGTVANVFLFVHNFSPVMTGSKKRPRQVILSHMAVANALTLFLTIFPNNMSAFAPKTPPTELKCKLEFFSHMVARSKNLCSTCVLSIHQFVTLVPVNRGKGKLILRASVPNLWNYSCYSCWFYSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGMVFLKFSHDATFMTIMVWTSVSMVLLLHRHHQRMQHILTPNQDARGQAETRATHTILMLVVTFVSFYLLNCICIIFHAFSIHSRLFIRLVSEVLAAVFPNICPLLLIFRDPKDPCSVLFKC", "length": 307 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K9J7G4-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r242", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSVHDKSVKTTEEVALQLLLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMMAFAPKTPPNELKCKLESFSRLVARSTNLCSTCVLSIHQFVTLFPVSRGKGKLILRASVQNLASYSCYSCWFFSVLSNIHIPIRVTGPQITDNNTDSKSNLFCSTSGFIVGIVLQFAHDATFMSIMIWTSVSMILLLHRHCQRMQDILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNCICIIFHAFFIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSLLFKC", "length": 306 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K9J7H2-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r256", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSLKTTEEVALQLLLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILGHMAVANALTLFLTIFPNNMMAFAPKTPPNELKCKLESFSLLVARSTNLCSTCVLSIHQFFTLFPVSRGKGKLILRASVQNLASYSFYSCWFFSVLSNIHIPIRVTGPQITDNNTDSKSNLFCSTSGFIVGIVLQFAHDDTFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQNPRGQAESRATHTILMLVFTFVSFYLLNCICIIFHAFSIHSCLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 306 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K9JA28-1", "protein_name": "Interferon lambda receptor 1", "gene_name": "IFNLR1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MSAWRIRVLATLCFLWQPRVHGQLPPPQNVTLLSKDFDMILTWTPGEGSPPDVLYTVRYESKTRMDKWIKVPHCRNIHSVSCNLTCVIPNFFIKFRAQVKATSGRFHSPWVKSQFKEYHLDVELAPPLLNVNVKENVIHVNATFPMAICVESLPWMYDFNLWEAGSEDKKQYKSIFRKKAVTIDTTALRGNYCFNARSSIQSIDFKHSKFSQPVCMQLNYEGEWKFPFSATIPVFVLLILLTSASIIWLLKQDAKHKKMPQTLDLSNCKIAGPTFCCELRENEFLTDCLICTDKPMSQGKKNKTLAQNNQMWMASFLPSSSSEEEEEEEEEDSSSFIPYTEMLQFPRKHFNFQTPRTADAETILDSTSGVLSVVGGSTLDLSALGFSFFPIRKNEMDTSGSQGNEKASHSHSSSLGRISLTDVRFPGPREHGQHGTDSNDCLEVSLLHTLMNSSCTRLPADEHCLYKKDHDFTICYQKPTLDQPVQVSENPLLNEDPSMEKFIYLQTLQVAEDEGFASDCDSGNFTEGTPPASTVLSDELRISDMEKRYDKKFKFKGYQHSHYMRRS", "length": 567 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "L7MU37-1", "protein_name": "Reproductive homeobox 3H", "gene_name": "Rhox3h", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSMKPERSISNWIHSNVEPAGRNLFQVNGHRSALLPELPQDYHRASRSVNGCETKMDSTQGTKVLPAEESRNEEDGGQVESALGATAARGRGKEALNGESPAAAGTAGLVEEDRNKEDGGTKGGEKNEQEVREQIPEHVEGESDQAEAPRQVPRRRLHHRFTQWQLDELERIFRMNYFLSLEARKQLARWMGVNEAIVKRWFQKRREQYRWYKRL", "length": 215 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7MU51-1", "protein_name": "Olfactory receptor", "gene_name": "Or4a76", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGQSNNVTEFVLLGFTQDPAGQKALSVMFSLIYIVTMVGNLLIVGTVIASPSLGSPMYFFLASLSLMDAIYSTAITPKLIVDLLCEKKTISFRACISQLFIDHLFGGVDIVILLAMAYDRYVAICKPLHYLIIMNRRVCILFLVMAWAGGLAHALFQVLAVYNFPFCGPNIIDHFGCDIYPLLLLACTDTYFLGLSIIGNNGAMCIVIFTLLLLSYGIILRFLKNHSQEGRRKALSTCGSHITVVFLFFVPCIFMYVRPVSSFPIDKFITVIYTIVTPMLNPLIYTLRNSEMKNSMEKLLQKTLSPSRIRLSSCCLCY", "length": 318 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7MU81-1", "protein_name": "BTB domain containing 35, family member 17", "gene_name": "Btbd35f17", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGKTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANTWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7MU83-1", "protein_name": "BTB domain containing 35, family member 18", "gene_name": "Btbd35f18", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGKTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDQVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7MUB9-1", "protein_name": "Reproductive homeobox 2G", "gene_name": "Rhox2g", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MERQSINYKLDVGPEEDEENANGIKTLMVLLAGEGRNEGESGRGLPGSGVSAAEGYRAGELSAGGLAAPVADLMDNNNQEDLGATGCAQEKEKQPEEPVPDSMGDLENVKPMSGPWSTVNPVRVLVPEFLHGWQQSFNVLQLQELESIFQCNHYISTTEAKCLARSMGVSKATVQEWFLKRREKYRSYKRL", "length": 191 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N1X6-1", "protein_name": "F-box/WD repeat-containing protein 15", "gene_name": "Fbxw15", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAIHLPCLPMMKILSYLDAYSLLQAAQVNKDWNELASSDVLWRKLCQKRWLYCDMDTLQLQGKETWKQFFIDRIWQERAKFRAKAKDFTYKEIPLMCGLFGYACYISGCGLTRKGQDKSVVCMVNSKNTISTWDVHKSVITWKSPEQPASIKLLTTLPEMHIAVTVDIQSTIKLWDCHNREALATNNLKSPCKSLKAVFTKDGPIVLIGDTLGNIHIFRIPDLYLISTVNVLPYGFDGIYCSPQKKWVLLSKKHPHILPKVFYMSSFLRTSEFSAPVSTVLKLSLYERVFWTPRREDRITLMSRSGFPQVKMFETYDIKLEEFGNKRIVKGKLIASFELQCHKVNPQRFGVSDKNVIVCSTESSLLLFDINGLRLKTFQYCPEMIVKLSVDPLHVIVICNTGSMDVYAWEERSLLLRKCYRLHIERPLPLYGFIYKAACDDVSIIQLITDELSLSSLTSYALNICS", "length": 466 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N1X9-1", "protein_name": "Demilune cell and parotid protein 1", "gene_name": "Dcpp1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFQLEAMLALLILAFLGTPTVLTQDYHGPEVGKHSCTSAPEGKNITSIRVFLKGRLIVGIQLNYDDNKDGQVYGSTAGKEMVARLSKEEHIIAAQGTYTPSALTQIIFTTNQPRQLMVGYYVGNSEYSSFPNDPSHVLKGACVSWRAGGIKSILFLWGSENSSCVKYGHSG", "length": 171 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N1Y3-1", "protein_name": "PRAME like 51", "gene_name": "Pramel51", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MIHSKERKYRLGLLEPGVTAFPCPNMVICLHCPDQDDSLEEVTEECYSPPTLQNLAIQSLLRDEALAISALTDLPQSLFPVIFEEAFTDGHIGILKAMIPVWPFPYLSLGKQINNCNLETLKAMLEGLDILLAQKVQTSRCKLRVINWREDDLKIWAGSHEGEGLPDFRTEKQPIENSPGCEVKKELKVTTEVLRMKGRLDESTTYLLQWAQQRKDSIHLFCRKLLIEGLTKASVIEIFKTVHADCIQELILRCICIEELAFLNPYLKLMKSLFTLTLDHIIGTFTLGDSEKLDEETIFSLISQLPTLHCLQKLYINDVPFIKGNLKEYLRCLKKPLETLCISNCDLSQSDLDCLPFCLNICELKHLHISDIYLCDLLLEPLGFLLERVGDTLKTLELVSCCIVDFQFSALLPALSQCSHLREVTFYDNDVSLPFLKQLLHHTALLSQLIYECYPAPIECYDDSGVILTHRLESFCPELLDILRAKRQLHSVSFQTTKCSKCGGCYIYDRHTQCCRFVEL", "length": 520 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N1Y5-1", "protein_name": "Olfactory receptor", "gene_name": "Or11g25", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKTLSSPSNSSTITGFILLGFAYPREGQILLFVIFFIVYILILMGNASIICAVYCDQRLHTPMYLLLANFSFMEIGYVTSTVPNMLANFLSDTKVISFSGCFLQFYFFFSFGSTECFFLAVMAFDRYLAICRPLHYSSLMTGRLRNTLVTSCWVLGFLWFPVPIIIISQMSFCGSRIIDHFLCDPGPLLALACSRVPLIEVFWSIIMSMLLVIPFLFIMGTYILVLRAVFRLPSREGQKKAFSTCGSHLTVVSLFYCSVMIMYLSPTSEHEAGMQKLVTLFYSVGTPLLNPMIYSLRNKDMKNALQKILRT", "length": 311 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N227-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r125", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSMKTTEEVALQIILLCQFGIGTVANVFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMSAFARKTPPTELKCKLEFFSHMVARSTNLCSTCVLSVHQFVTLVPVNRGKGKLILRASVPNFANYSCYSCWFFSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGMVFLQFSHDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQDARGQAETRATHTILMLVVTFVSFYLLNCICIIFHAFSIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 307 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N255-1", "protein_name": "Predicted gene 3099", "gene_name": "Gm3099", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSRLLRLCLKGNGDEGETRPKKKEEGILSHEKGRRKLFWRRHRSARNTSTQNSNITNQISNINEVEELKLHIRKISNERKEMCEILNVYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMTQFIIGSMQYSMELIEDNYSYSIKEDHLLRECTQLNKKVRILLNENRKLLVEQAGTQVSCGEEKRFCEEASKNICASSAKEQQLP", "length": 205 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N259-1", "protein_name": "Demilune cell and parotid protein 3", "gene_name": "Dcpp3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFQLEAMLALLILAFLGTPTVLTQDYHGPEVGKHSCTSTPEEKNITSIRVFLQARSIVGIQFNYDDKDGQVYGSTAGKEMVARLSKEEHITGVEGSYSPSALTQIVFTTTQPRQLMVGYHVGIYQYSSYPDDPSFVLKGACVSWRAGGIKSILFLWGSENSSCVKYGHSG", "length": 170 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N270-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r123", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSLKTTEEVALQLLLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILIHMAVANALTLFLTIFPNNMSAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIHQFVTLVPVNRGKGKLILRASIPNLWNYSCYNCWFYSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGMVFLQFAYDATFMIIMVWTSVSMVLLLHRHRQRMQHILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNFICIIFHAFSIHSHLFIRLVSVVLAAVFPSICPLLLIFRDPKDPCSVIFKC", "length": 307 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N273-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r118", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSVHDKSVKTTEEVALQLLLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMMAFAPKTPPNELKCKLESFSRLVARSTNLCSTCVLSVHQFVTLFPVSRGKGKLILRASVQNLASYSCYSCWFFSVLSNIHIPIRVTGPQITDNNTDSKSNLFCSTSGFIVGIVLQFAHDATFMSIMIWTSVSMILLLHRHCQRMQDILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNCICIIFHAFFIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSLLFKC", "length": 306 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N275-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r169", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSQNKSVKTTVEVALQILLLCQVGVGTVVNIFLFVHNLSPFLNGSQQRPIKVILANLALGNTLILLFAFPNNIRVFIPREFPTDLKCKLGYFIWLVARSTNMCSTCSLSTYQLVTLAPGTWGRVMLHGRAPKFVRYTCYSCWLFSVLNNAHIPMKVSGPQKTHNDTNTKSKWVCSTTGFSIGMRILSFAHDAVFISIIIWSSVSMVILLNRHHQRLQHIQSPNQKLRFHAETRAAHTILMLVVTFVTCYLLDCICTSLHISFVDSRVWLRRVKEILAVSFPTFSPLLLIFRDPKDPCSLPFSC", "length": 304 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N288-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r151", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSDHGKSVKTTEEVALQILLLCQFGVGTLANVFLFVHNFYPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMIAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIYQFVTLVLVNRGKLILRASVPNFVSYSCYSCWFFSVLSNIHISIKVTGPQITDNNTDSKSNLFCSTSGFIVGIVSLQFAYDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQYRRGQAETRATRTILMLVVTFVSFYLLNFICIIFHTLLMHSHLFIRLVSEVLAAVFPSISPLLLIFRGPKDPCSVLFNC", "length": 305 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N2A6-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r116", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQILLLCQFGVGTVANVFLFFHNFSPVLTGSKQRPRQVFLSHMAVANALTLFLTIFPNNMSAFAPKTPPNELKCKLEFFSHMVARSKNLCSTCVLSIHQFVTLVPVNRGKGKLILRASVPNLWNYSCYSCWFYSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGMVFLQFSHDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQDARGQAETRATHTILMLVVTFVSFYLLNCICIIFHAFSIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 307 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N2B4-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r128", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQILLLCQFGVGTVANVFLFVHNFSPVLTGSKKRPRQVILSHMAVANALTLFLTIFPNNMSAFAPKTPPTELKCKLEFFSHMVARSKNLCSTCVLSIHQFVTLVPVNRGKGKLILRASVPNLWNYSCYSCWFYSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGMVFLQFSHDATFMTIMVWTSVSMVLLLHRHHQRMQHILTPNQDARGQAETRATHTILMLVVTFVSFYLLNCICIIFHAFSIHSRLFIRLVSEVLGAVFPNICPLLLIFRDPKDPFSVLFKC", "length": 307 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N2C2-1", "protein_name": "Predicted gene 2974", "gene_name": "Gm2974", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLLRLFQKENGDEGETRPTEKEEGILSHEKERRKWFWRRHRSARNTSTQNSKMTKKRSKINELEELKLDMRKISNDMEEMCGILNLYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLNENVRILLNENRRLLVEQAGHKCPVGKKRGSLRRPARTSVSQVPRNSSVI", "length": 205 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N474-1", "protein_name": "Spermatogenesis associated glutamate (E)-rich protein 1E", "gene_name": "Speer1e", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "ARRHTSSTAPDLSKKEFKKEKERLTTELHLLIQLRNEQRDHLIDFKESSNYNRTKPTQKKNPFYEQLRSTKNQVLSSVHKLEMGIIEAQENIQELNKWIDYFTNLHSQLLMEKNLKMSITQNQKNKEVEIDWALIEKYLVDVNLNGRTGADQQP", "length": 154 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "M0QWR4-1", "protein_name": "Aly/REF export factor family member 14", "gene_name": "Alyreffm17", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MADKMDMSLEDIIKLTKIQQRRHDRPDSRVNRGTGSKRYRPAFTHGGRNRLAPYCRPKQLPDKWQHDLFIGGFRGQNHVDTGGKLFLSNLHFGVSDADIQLLFAEFGTLKKSAVHYDRCGRSLGTAQVHFERKADALKAMREYNGAPLDGRPMNIQLATSQIDRQGRPAQSKNRGGMTRNPGSGVLSGGGTKKWTLGGSQGRGRGTIRNSKLQQQQQQQKQKQQQQQQKQQQKQQQKQQQQLSAEELDAQLDAYQEMMDTS", "length": 261 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "M0R3T3-1", "protein_name": "Peptidase S1 domain-containing protein", "gene_name": "ENSRNOG00000067174", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRFLVLCLILSLGDYGAFPLIQSRIHRGCKGERHSQPWQVAMYHYDKAVGWGWHPSPTTMSTSPSHNKVRLGQHSLDADGDTGQDVPVRHSIPHPLYNRSLQMPTFLSPDADNSHNLMLRQLREPANTTEAVRVTEEPTEEAKLGSRCLASGWGSTRPDKCMPGMLQCVDLTLMSSDVCTYAYSQRVTESMLCAGHQEGSRDTCMGDSGTTLICDRMLQGITSWGGNPCA", "length": 230 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0R777-1", "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "Smokwl5", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASKSKEKTLGSHYKILSYLGQGSFGTVNLAWHLKTQALVAIKMLEISKETISSILSERAILETLHHPNIIRLFQVLITSSHVNFVLEYAPGGSLFELIKEGGPLQEEVAKKIFGQTVSAVKYCHNLDIVHRDIKPQNILTDAEGNGKLTDFGLATKFRPGTLLKELCGTKEFYAPELVLREPYNGKKTDVWSLGVLLYFISTGYCPFRGVTTKDMEKKIATGTYTIPTYFSGQLENLIHQILTVSPEMRPSIEDIEKHPWVRKCEVNIPTITCPDYKIVEMLCGMGYNANKILESLQKKKYDEPMAAYLILKDKVRQEIEHGTTTSDMPVDQGPLPPQSPAHHSVSGLPLKRRASEPNFGLLHIWPPGEQVARHNVARSVSMPPIALYGTKKQNSTSTSALHSRPVASPCVCNTILEIEIPLPTKQDFDMKTSSPPQRIGYFQRLCQRIRDCLSRLCCFLWAPKVHSPRKWLP", "length": 474 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0R9M1-1", "protein_name": "Olfactory receptor family 52 subfamily N member 1B", "gene_name": "Or52n1b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSLLNVSSLTPASLILNGIPGLEEVNLCIFFPLFTMYSIALTGNFGLIYLIYSEEVLHRPMYIFLALLSFTDVLMCTSTIPNTLFISWFNFKKIDFKACLAQMFFVHTFTGMESGVLVLMVLDLYIAMCYPLRYATILTNVVIAKAGMLTFLRGVALVIPFIFLTKRFPYCKGNVIPHTYCDHISVAKISCGNVQINAIYGLMVVLLIGDFDIPCITVSYTMILWAAVSLSSADARQKAFSTCTAHICAIVITYVPAFFTFFTHRFGWHTIPSHIHIIMANLYLLMPPTMNPIVYGVKTKQIQKRVIRFFFKGRENSSHKF", "length": 321 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0R9X6-1", "protein_name": "Paired immunoglobin-like type 2 receptor beta 1 like 2", "gene_name": "Pilrb2l4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MALLVSLPEQNLAMAWILLLLLLAACLHTGNSAGYQKTQDYGVNQPEQLTGIQGGSIEIPFSFYFPWELAKDPQMSIAWRWKVFFGEVIYNSTLLFLHEHFKGRLIMNWTQGQTSGVLRILNLKANDQSTYFSRIFLQATEGMKLWQSRAGTKLIIHALSTTMASPSIIPSAVPTAGLENTRGQRNPSLLNLGAMVGMVMAKVVVIIPLYGWVIFLWWKQRLPTARISHQVSLHHTPCIPQSSMSSLWESELVAAGFSCESHSWITPTSAMGARIPSPWNQGPPVCLWA", "length": 289 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RAD6-1", "protein_name": "Olfactory receptor", "gene_name": "Or1f19f", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRSTNQSSVSEFLLLGLSRQPQQQQLLFLLFLIMYLATVLGNLLIILVISTDSHLHTPMYFFLSNLSFVDVCFSSTTVPKVLANHILSSQAISFSGCLTQLYFLCVSVNMDNFLLAVMAYDRFVAICHPLYYTTKMTHQLCVLMVSGSWVTASLNALLHTLLMARLSFCGDNIIHHFFCDVTPLLKLSCTATNLNELMILTEGAVIMVTPFVCILISYIYITNAVLRVSSFRGGWKAFSTCGSHLAVVCLFYGTIIAVYFNPVSSHSSEKDTAATVLYTVVTPMLNPFIYSLRNNDLKGALRKVVHRKI", "length": 309 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RBH5-1", "protein_name": "Surfactant associated 2", "gene_name": "Sfta2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEPSMCLFLLLTLLCSSLAGPTKVTLQVKLTEASQAKTSQDSGFLDMLQKICLLLHLSPGTNVTLHHKGPPHHLTCRA", "length": 78 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RCJ6-1", "protein_name": "EF-hand domain-containing protein", "gene_name": "AABR07013776.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MADQLTEEQIAEFKEAFPLFDRDGDQTVTTKELGMVMGSLGQNPTEAELQDMISEVDADGNGTINFPEFLTMMARKMKGTDVEEEIREAFRVFDKDGYTSAAEFRHVMTTLGEKLTDEEVDGMIREADMDGDGQVIYEEFVQMVTAK", "length": 147 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RCP1-1", "protein_name": "Leukocyte immunoglobulin like receptor B3", "gene_name": "Lilrb3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVSTLTALAYLGLILGSENPVLSGAFTKPTIKMVPSNVVTTGKQVTIFCEGSSHAKEYRLHKEGSPDYLTPTTFLETENKAKFSISPIQWNNAGQYWCSYRSLTNKLRQSDIMELVVTGVILGEVTLSALPSYVVTSGRNVTLQCASQVVYDRFILMKEDEKFSTAMPSWKIYPVLWGAIFTLGPVTSNQRWRFTCYGYYLSSSLIWSKPSNHLELLVSGTLHKPILWAHPGSMVTSGSPVTIWCEGDQETQTYVLYRQGSLESWNRQTQKDYNNKAEFTIPSVTYLNAGHYFCYSYTSAGWSEHSDTLELVVTGVYKKPIFLALKNPIVNLGVTVTISCTSNQSFNCFLLMDDDQKIYRFFDLQYSYSGESLARFQVGPITSRQRWRFRCYGYYTDNPQVWSEASDPLDFLVSGNLQKPTLWAEPGSVIESGNSVTIWCEGTMETQIYFLYKEGSPSSWLRQTPKEPGNKAMFFIAFMEKHNAGQYRCYCYNFGGWSQHSDTLELVMTGVHHGKPTLSAFPSPMVTSGGNVTLYCASSTIYDWYIVTGQDLKFSRFQRAQFIPTEMSQALFSEISVASRKKGPFRCYGFNESTPHLWSEASNPLEIHVSGVSRKPSLLNQQGPVLAPGENLTLRCSSELSYDRFSLSKEGRSDLPQLSVSQSQTGEYYANFFLYSVDFSIAGQYRCYGASRFSSEWSAPSVPQDILVTGHPPITPSLSVNPGTIVSSGENVTLLCQSSIPMDTFFLFKKGDAYPYMHQRLKFQGPQCKAEFSLSAVTPNIGGIFTCFGSQSSSPYLLSHPSVPVEIKVSGLAKYQKSLIWVSVVFFLLFFVLTLFFFLRLWHQNKHRKGVQTKIDLQHPEGAVEPKSIVGHLQKSSRPAPAIQEEILCEKRWPGREITEVSASDATVKVTRSADNVELGILSQHQDDPSIHLYAQVKPARLRRAQTTSSSLFPKELQHSKHRQKNRDQVIDQQADTSQDSHAVIYAQLHIMTPRQGRQTSLFPGRIC", "length": 1008 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RCQ2-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "LOC100361204", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDSSIPDPEADLIQLNGSYHTETSPCVIESRVMILLSIIIAFFGLAGNAMVLWLLAFRMRRNVFSVYILNLAGANFLFLCTHTAFSLEKIIVLFHSVHIHIPLLFYTLSTLAYLAGVSMVTAISAEYWLSGIWPYWYQGQRLKHTTTVICTGLWGLALLLSLLEGKSCGFLGSTYNQDVCWKLDFIIVAWLLVLFAVLSRSIQVLLVRIFCGSQRTPVTKLHVTIVLTALVLVICGFPFGIIFYLLYWTTEVYYIMPCNSFHETILLLSYINSCANPIICLLVGSIRHCRFQCGTLRLLLHRAMQDIPEEEGEELEEVVGERVQSSIP", "length": 328 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RCW7-1", "protein_name": "Uncharacterized protein", "gene_name": "Pilrb1l3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MALLVSLPEQNLAMAQLLLLLLSAACLHTGNSAGYPKKNVFSVDQPAVLSGVQGGSIEISFSFYFPWELAKVPQMSIAWRWKNYHGEYIYNSTQPFIHEHFKGRLIVNWSQGQTSGVLRILNLKENDKATYFSRVFLPTTEGMKSWQSVAGTQLIIIHAPSTTVVSPSIIPSVVPIAGLEDTRGKRTPSLLNLGAMVRMVVSKVVVIIALYGWVIFLWWKQRSAWSLLSFLTTWKSEEQMQMNTAPAPKEFK", "length": 252 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RCY4-1", "protein_name": "Retinoic acid early-inducible protein 1 domain-containing protein", "gene_name": "AABR07000137.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSSAPLGSLGRKSKNQSLGLDMLGTVLSTDSLSCTFTVKYRSSPGQCSVNGKPLLLFNDERQNSPVGKPEKKGNATKVCAELNQSLKDIFQKMMNLESWLFESKGNHTLQVTVQSQYNQGIFMDGCWVFTIDRQYPFYFYPKIMTWRESHPDASRTVSQWQNNRQVAQSLRTCSMGDFSQCLRKLLTDSREVPRSTITTLDPTQPSSAIQIPPTVDSASSVFTTWSQYIFVLILCLAILIINALIP", "length": 246 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RD07-1", "protein_name": "Uncharacterized protein", "gene_name": "ENSRNOG00000064269", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRMMAMQMMTNSISDAMERYKELIQVNSSYNIRQSQLLREQAQLKNNIQILLNEKRELLVEETELPASSVEAKRLCEEAGMNICDPRAKQQQV", "length": 93 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RDP5-1", "protein_name": "Zinc finger protein 353", "gene_name": "Zfp353", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDVAETPGASQTVPCNTQPSPVESSQLVSGQSSEMPTWKKTVMASACCNPQETACTQNSTAHPGKASDFYFGEPSETASFIQQVVSAEQKSSPAGSCLMNLSSTTKSCLSHPLKTEVLDTRKTLCNEGHWGRTLNSDKTLLIQITTMYESQWRTLGNHPVAPSGYHEGQAPNMDHLVDSVSNQTFIGDLEMEPSCNHVLYTDQFITSFSEQNPFGDQQRSPVADNRFYADQKILPNGYQTFYEPQMSTNYQITCVCGQNVCRCQEILLSGEHLLSEYQTSGYRYDQDLIVNLQVTSPIGGEPLHDSQIPNSNFDTTSCGTKRTTSSEEDNLAWHPETSLSSEETFLDQMRTSVDQNVYPSHNGTLKIEESLEPQVTSLSNQAPYVGESSDTSNSPLIQIQPQEISSASGLDQGQHPEIKLDLKTQSPVSLKNPHNSKRYCCTYQGCKKSYKKSQHLKDHMKKHTGVKPYMCNKPGCDWKFFRLVDLNRHKQKHSGERPYPCPMCNKNYSRFYYLKQHLRSHIQASPTTAT", "length": 530 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M9MSI7-1", "protein_name": "Uncharacterized protein", "gene_name": "Dmel\\CG42818", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MFIHQREQLPFKHNEQDPNYLAPVIQKRKPMDKDPRNPLKRLKFLQEFPTQSSKGDLDDLKYPTQLEGRHDSPKYDKTFHTEIHANNETDSQELENIILEKNLQDSKTEFQENRASQPKNMHSFQIPEAIESHFNNKELQNENDLHKGLKQQYRSGSEQDKSGPENVREIASKLILQWAENQRSLLDSFVKAITDVLKVHDSKLNMKINISPRDIMILKDMLKQLLESIMQLREGSTSTRARIVLNKWIETQKSLIDSFSQAIQNTNQNVDNIANVYEVMENLNKNLRELVILLSDKESFPTTESSSSQQTTSIYATTTFYLTSSTFGSTHPIVDENINRVNIMGNLIKGLRNIMVQMDETNKTSSSTSYTTTESTYIQPSTSTYLNAEVTTSHPTTSTYEVTNIITDESKIKDMFNLIKGIEDLISQYNGKHKFTSTTSLTGKSNSREPTMTTYSSAGGITSHSFTTTSPKTVTTSSSHSTTESSPSHPTTSNYEVTVFDQDSHKFKVMKNLIKELKGLIEHFSDTKNITSTTYSTGDSKSFQPTATTPDSTDRSSSQPITFPESTTSTTNLQSTITNHLSTESTSSQLNTTLSITGTTTPNLTTSTHDFKDQINDDDSKSLKHLIKILSDLVYSLNDKNNIKSTSQLTTESTFNSSINITNSTTVASSTFSTTESMAIHSTPYLSTREITVFQFNDVENINPIISNNSTTVTTNIHSSTYTTSTTDNTTSYPNLSTTESSPTFDSTISHSNTSSQTRSLGSYKDKIKNIVELLKKLRKIQKTLADKSKGQLSPMLISRIKAVLKQIVAGNIDSVNGDSTELEILLSTTVNPNEDTTDLTMEKLLKLFDDFERMYNVLLDDSIQSTTQSTTQNNTIFSTTYSTIFSTTQSISTTSPTQYALTSSTPNTSTTSHSSTPSSINNLRSDESNNHQPIVDAIQQLKMALYHDFYAFKKSQEERMEKILQLLNGKPIDRRTKTIAKPRTIRKKVSREIQKRNSDVKEDKIHHYKADKFIKNPKNGNQDSHIPKPILNSARSKIKDVPLKLSAIKVNGGLKHLPSKRKANEEVSAMHEIFPEPVSILPHK", "length": 1085 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "O08640-1", "protein_name": "Keratin-associated protein 14", "gene_name": "Krtap14", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSCNSCSGTFSQSFGGQLQYPISSCGSSYPNNVFYSTDLQTPITHQLGSSLHSGCQETFCEPTNCQTAYVVSRPCQRPFYSQRIRGPCRPCQSTFSGSLGFGSRGFQSFGCGYPSQGFGSHGFQSVGCGTPTFSSLNCGSSFYRPTCFSTKSCQSVSYQPTCGTGFF", "length": 167 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "O21032-1", "protein_name": "Large ribosomal subunit protein uL16m", "gene_name": "mrpl16", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKIPNRQKFTKNHKRNLITKETRKTGLVLGNYGIKATETGYLKMKQMERIKGDLVKKLKDNMDIYFNFYPLFGLTNKGTARMGAGKGEVSEWYVLVKKGSIVVEFIKSRMTAGAMQKVIRYSANKWPIKVRMTQIKQGLYEKKI", "length": 144 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "O21042-1", "protein_name": "Cytochrome c oxidase subunit 1+2", "gene_name": "2", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKILEIYDKQIAEKEGNIFIFISKWIISVDHKNIGTMYTNFSILAGIVGTLLSLVIRMELSTGNMLDGDGQQYNVIVTAHGLIMIFFVVMPAMLGGFANWFIPIMVGSPDVAFPRLNNISLWLIIVSFFLLLTSSCVGIGVGTGWTVYPPLSTMEYHPGHAVDVGILSLHIAGASSLLGAINFLTTVFNMKIAGLSWSKVSLFVWSILITAVLLVLSLPVLAGGLTMLITDRNFETTFFDPIGGGDPILYQHLFWFFGHPEVYILILPGFGLVSIILSKYSNKGIFGVKGMISAMSAIGFLGFLVWAHHMYTVGLDVDTRAYFTAATMIIAIPTGIKIFSWLATLWGGVIKITTPMLFVIGFLVLFTIGGLTGVVLANGGLDISLHDTYYVVAHFHYVLSMGAIFAIFAGYYYYYSIMNSTRLFGVVRYNEQLGRIHFWTMFIGVNVTFFPMHFLGLAGMPRRIGDYPDAYIGWNLIASYGSLITAFGLLFFVVNIFTPYIRRSVNIKNGAIILMGLDFARDWQIGFQDPATPIMEGIIDLHNYIFFYLIVVAVFIGWVMGRILWRFSYKWSYPTIGDIEIFKNFTAYNQIIHGTVIEIVWTLIPTVILYLIAIPSFTLLYAMDEIINPTVTIKIIGHQWYWSYEYGDNASNLIEFDSYMVYERDLAEGQLRLLEVDNAMVVPVKTHIRLIITSGDVLHSWAIPSFGIKVDAVPGRLNQIGLYVKREGTFYGQCSELCGVDHGFMPIKVQAVKLGEYFSKLNEK", "length": 764 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "O21049-1", "protein_name": "Cytochrome c oxidase subunit 3", "gene_name": "cox3", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKGFFENLFRQNVRSVINTGKKVGARAAAREIINQEWGYPLANHEVLFLTNVYQPKHMKRHPFHIVRGTVAPLAVTLPLGFFVLNYFGVISSKLGLLIALSSFIGGLVIWTISIIFDSLYDQQHTYEVKRGLVMGMMMFIISEVMFFFSFFWSYFYISLSPNIAIGCVWPPYGLTVYSYMGLPLLNTVLLLLSGAILTDGYTILTEQKAVHEKNEKVLAVEEAFKNLMNLYKTKNSINTLTFVDERRDKFFGKESRQEDKIAEQKLIAISAGVKELRDLDWDLYFFENPENIEPNYKEPTNLSVIEYALITIYLKKRNKVIKTRLYFTLLCAVVFLACQGYEYFFAPFSMNDGIYGSLFFLLTGFHGFHVLVGSILIGIITIRFIVGNFNLLNVGTNFQIYKNKSTGFACTLFYWHFVDIVWIFLYIVIYWWGSR", "length": 435 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "O23373-1", "protein_name": "Formin-like protein 3", "gene_name": "FH3", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MGRLRLAFLAISLVVFVCVSEEIFSRGGLNLLRFSVYGEDVAEQTWIHQNPRRKLISYPKKFSVSAPNLAFGPAPSFAPGPGPSFAPGPAPNPRSYDWLAPASSPNEPPAETPDESSPSPSEETPSVVAPSQSVPGPPRPPPQREKKDDILMKLIIAVASTAVLTFVFVALMFLCCFKRNCNNAVGSRDGPRDEGPLLRLSTGSTENSPTVASTSRKMFSVASSKKRSFLSRVSLKRNGHEFSTAESSSAAGLPPLKLPPGRSAPPPPPAAAPPPQPPPPPPPKPQPPPPPKIARPPPAPPKGAAPKRQGNTSSGDASDVDSETGAPKTKLKPFFWDKMANPDQKMVWHEISAGSFQFNEEAMESLFGYNDGNKNKNGQKSTDSSLRESPLQYIQIIDTRKAQNLSILLRALNVTTEEVVDAIKEGNELPVELLQTLLKMAPTSEEELKLRLYSGDLHLLGPAERFLKILVDIPFAFKRIESLLFMISLQEEVSGLKEALGTLEVACKKLRNSRLFLKLLEAVLKTGNRMNVGTFRGDAQAFKLDTLLKLSDVKGTDGKTTLLHFVVLEIIRSEGVRALRLQSRSFSSVKTDDSNADSSPQSVERYRSTGLQVVTGLTTELEDVKRAAIIDADGLAATLANISGSLTNAREFLKTMDEESDFERALAGFIERADADFKWLKEEEERIMVLVKSSADYFHGKSAKNEGLRLFAIVRDFLIMLEKVCREVKETTKTTNHSGKKESEMTTSDSNQPSPDFRQRLFPAIAERRMDSSDDSDDEEDSSPS", "length": 785 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "O35698-1", "protein_name": "RNA-binding motif protein, Y chromosome", "gene_name": "Rbmy", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAETNQPGKIFIGGLNIKTRQKTLQEIFGRFGPVARVILMRDRETKKSRGFAFLTFRRLADAKNAVKEMNGVILDGKRIKVKQARRPSSLESGSKKRPPSFSRTRGASRILKCGRGGRSRARSGPSCEGNLGGDRYTPNFNVSSSGRHFAVKRNPSSKRDDPPSKRSATSAQTRSNTGLRGREPHRREISRNMPRGEPASSRRDEYPLPRDYGQSSNDRKYESTSRGYCDYGNYHSREESASKVFSDHAGYLGGRDRDFSEYLSGNSYRDTYRSYGRFHEAPSARGGNNRYDDYSNSQDGYGGRGEPYISNRSNIYSSDYERSGRQEVLPPPIDREYFDREGRQERGHSPKDGLYSASRESYSSNTKIWGIPWRSWRKQI", "length": 380 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "O60309-1", "protein_name": "Leucine-rich repeat-containing protein 37A3", "gene_name": "LRRC37A3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTSAQCPALACVMSPLRFWGPWPLLMWQLLWLLVKEAQPLEWVKDPLQLTSNPLGPPEPWSSHSSHFPRESPHAPTLPADPWDFDHLGPSASSEMPAPPQESTENLVPFLDTWDSAGELPLEPEQFLASQQDLKDKLSPQERLPVSPKKLKKDPAQRWSLAEIIGIIHQLSTPQSQKQTLQNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVKPADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPMEHELSISEQQQPVQPSESSREVESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLTIAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSFQSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLDLGFTITPESMTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLELTITTKPTTEVKPSPTTEETSTQLPDLGLAIIPEPTTETGHSTALEKTTAPRPDRVQTLHRSLTEVTGPPTELEPAQDSLVQSESYTQNKALTAPEEHKASTSTNICELCTCGDEMLSCIDLNPEQRLRQVPVPEPNTHNGTFTILNFQGNYISYIDGNVWKAYSWTEKLILRENNLTELHKDSFEGLLSLQYLDLSCNKIQSIERHTFEPLPFLKFINLSCNVITELSFGTFQAWHGMQFLHKLILNHNPLTTVEDPYLFKLPALKYLDMGTTLVPLTTLKNILMMTVELEKLIVPSHMACCLCQFKNSIEAVCKTVKLHCNSACLTNTTHCPEEASVGNPEGAFMKVLQARKNYTSTELIIEPEEPSDSSGINLSGFGSEQLDTNDESDVTSTLSYILPYFSAVNLDVKSLLLPFIKLPTTGNSLAKIQTVGKNRQRLNRVLMGPRSIQKRHFKEVGRQSIRREQGAQASVENTAEEKRLGSPAPRELKQPHTQQGPEKLAGNAVYTKPSFTQEHKAAVSVLKPFSKGAPSTSSPAKALPQVRDRWKDLTHAISILESAKARVTNMKTSKPIVHSRKKYRFHKTRSRMTHRTPKVKKSPKVRKKSYLSRLMLSNRLPFSAAKSLINSPSQGAFSSLRDLSPQENPFLEVSAPSEHFIENNNTKDTTARNAFEENVFMENTNMPEGTISENTNYNHPPEADSAGTAFNLGPTVKQTETKWEYNNVGTDLSPEPKSFNYPLLSSPGDQFEIQLTQQLQSVIPNNNVRRLIAHVIRTLKMDCSGAHVQVTCAKLVSRTGHLMKLLSGQQEVKASKIEWDTDQWKTENYINESTEAQSEQKEKSLEFTKELPGYGYTKKLILALIVTGILTILIILLCLIEICCHRRSLQEDEEGFSRDSEAPTEEESEALP", "length": 1634 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "O80489-1", "protein_name": "small monomeric GTPase", "gene_name": "SARA1A", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MFLFDWFYGILASLGLCKKEAKILFLGLDNAGKTTLLHMLKDERLVQHQPTQHPTSEELSIGKINFKAFDLGGHQIARRVWKDCYAKVDAVVYLVDAYDRDRFVESKRELDALLSDEALANVPCLILGNKIDIPYASSEDELRYYLGLTNFTTGKGIVNLEDSGVRPLEVFMCSIVRKMGYGEGFKWLSQYIK", "length": 193 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "O80614-1", "protein_name": "RING-type E3 ubiquitin transferase", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSSDMRDERFFYHRYLSVTNRTTPTTATNLPTSTSNMRSTSLMTPRVAHTSMSSGGDFPDDRFFHARHQSATDRAASNRSRAIMPISTTNVPSSTSNSPRVLQTSMSRRGTSPMSSSTRRSVQASMSARETVPSSTSTRSMQTSTSTPEIMPTSSRNVITSSEEVANTFTQTSYIQFGSLWETNTTPSTRSWPTVPSSNSPRVLQTSMSRRGTSPMSSSTRRNVQSSMSGRETVSSSTSTSSMQTSMSTPEIMPTSSRNVITRSEEVANTFSTQTPYIQFGRLWETNTTSSTRSRTTVPTSTTNVPSSNSSRVLQTSMSTRGTFPMSSSTRMSVQASMLAPGTVSSSMSTVEIMPTSARNMITMSEEVANSFTQTSYIQFGSLWETFKTVTKLSRVAMVENGECVICLEEWRKETYVTSSTSNMRTSSLMTLTRFIDEQISLRATVSSTRTTARLLTNESPATIRAVAMLPRVAMVEKGECVICFEEWSKSDMETELPCKHKYHLECVEKWLKIHTSCPQCRYKLSCVYKSFLML", "length": 535 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "O81153-1", "protein_name": "Proteasome subunit beta type-3-B", "gene_name": "PBC2", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSIFEYNGSAVVAMVGKNCFAIASDRRLGVQLQTIATDFQRISKIHDHLFIGLSGLATDVQTLYQRLVFRHKLYQLREERDMKPETFASLVSAILYEKRFGPFLCQPVIAGLGDDNKPFICTMDSIGAKELAKDFVVSGTASESLYGACEAMFKPDMEAEELFETISQALLSSVDRDCLSGWGGHVYVVTPKEVKERILKGRMD", "length": 204 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "P00757-1", "protein_name": "Kallikrein 1-related peptidase-like b4", "gene_name": "Klk1b4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWFLILFLALSLGGIDAAPPVQSQVDCENSQPWHVAVYRFNKYQCGGVLLDRNWVLTAAHCYNDKYQVWLGKNNFLEDEPSDQHRLVSKAIPHPDFNMSLLNEHTPQPEDDYSNDLMLLRLSKPADITDVVKPITLPTEEPKLGSTCLASGWGSTTPIKFKYPDDLQCVNLKLLPNEDCDKAHEMKVTDAMLCAGEMDGGSYTCEHDSGGPLICDGILQGITSWGPEPCGEPTEPSVYTKLIKFSSWIRETMANNP", "length": 256 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P01241-1", "protein_name": "Somatotropin", "gene_name": "GH1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MATGSRTSLLLAFGLLCLPWLQEGSAFPTIPLSRLFDNAMLRAHRLHQLAFDTYQEFEEAYIPKEQKYSFLQNPQTSLCFSESIPTPSNREETQQKSNLELLRISLLLIQSWLEPVQFLRSVFANSLVYGASDSNVYDLLKDLEEGIQTLMGRLEDGSPRTGQIFKQTYSKFDTNSHNDDALLKNYGLLYCFRKDMDKVETFLRIVQCRSVEGSCGF", "length": 217 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P02762-1", "protein_name": "Major urinary protein 6", "gene_name": "Mup6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKMLLLLCLGLTLVCVHAEEASSTGRNFNVEKINGEWHTIILASDKREKIEDNGNFRLFLEQIHVLENSLVLKFHTVRDEECSELSMVADKTEKAGEYSVTYDGFNTFTIPKTDYDNFLMAHLINEKDGETFQLMGLYGREPDLSSDIKERFAQLCEEHGILRENIIDLSNANRCLQARE", "length": 180 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P04071-1", "protein_name": "Kallikrein 1-related peptidase b16", "gene_name": "Klk1b16", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWFLILFLALSLGGIDAAPPVQSRIVGGFKCEKNSQPWQVAVYYHKEHICGGVLLDRNWVLTAAHCYVDECEVWLGKNQLFQEEPSAQNRLVSKSFPHPGFNMTLLTFEKLPPGADFSNDLMLLRLSKPADITDVVKPIDLPTKEPKLDSTCLVSGWGSITPTKWQKPDDLQCMFTKLLPNENCAKAYLLKVTDVMLCTIEMGEDKGPCVGDSGGPLICDGVLQGTVSIGPDPCGIPGVSAIYTNLVKFNSWIKDTMMKNA", "length": 261 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P04644-1", "protein_name": "Small ribosomal subunit protein eS17", "gene_name": "Rps17", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGRVRTKTVKKAARVIIEKYYTRLGNDFHTNKRVCEEIAIIPSKNLRNKIAGYVTHLMKRIQRGPVRGISIKLQEEERERRDNYVPEVSALDQEIIEVDPDTKEMLKLLDFGSLSNLQVTQPTVGMNFKTPRGAV", "length": 135 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P05817-1", "protein_name": "Prestalk D11 protein", "gene_name": "ampA", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MLNKLILLLILSSCLVLSVKSEVNVDCSLVRCAQPICKPHYRLNMTDSCCGRCEPCTDVACTLQVKYCQDGEVPTGCCPCTLPPTKPDCSLVKCARPVCKPYYRLNMTDSCCGRCEPCTGVACTLQIKYCKDGEVPTGCCPCTPQPTKKPDCSKVPCPKILKYCQEGELPTGCCPCTPQPTKKPDCSRVPCPKILKYCKEGELPTGCCPCTPQPTKKPDCSDVMCTMDIRYCKNGELPTGCCPCTPQETKVPDCSKAMCTMDIKYCKPGEKPFGCCPCRENLTQ", "length": 284 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "P06325-1", "protein_name": "T-cell receptor gamma chain V region 5/10-13", "gene_name": "Tcrg-V1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLLLRWPTFCCLWVFGLGQLEQTELSVTRATDESAQISCIVSLPYFSNTAIHWYRQKAKKFEYLIYVSTNYNQRPLGGKNKKIEASKDFQTSTSTLKINYLKKEDEATYYCAVCRSGTSWVKIFAKGTKLVVIPP", "length": 135 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P06349-1", "protein_name": "Histone H1t", "gene_name": "H1-6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSETAPAASSTLVPAPVEKPATKRRGKKPGMATARKPRGFSVSKLIPEALSMSQERAGMSLAALKKALAAAGYDVEKNNSRIKLALKRLVNKGVLVQTKGTGASGSFKLSKKAASGNDKGKGKKSASAKAKKLGLSRASRSPKSSKTKVVKKPKATPTKGSGSRRKTKGAKGLQQRKSPAKARATNSNSGKSKMVMQKTDLRKAAGRK", "length": 208 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P07628-1", "protein_name": "Kallikrein 1-related peptidase b8", "gene_name": "Klk1b8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRFLILFLALSLGGIDAAPPLQSRVVGGFNCEKNSQPWQVAVYDNKEHICGGVLLERNWVLTAAHCYVDQYEVWLGKNKLFQEEPSAQHRLVSKSFPHPGFNMSLLTLKEIPPGADFSNDLMLLRLSKPADITDAVKPITLPTKESKLGSTCLASGWGSITPTKWQKPDDLQCVFLKLLPIKNCIENHNVKVTDVMLCAGEMSGGKNICKGDSGGPLICDSVLQGITSTGPIPCGKPGVPAMYTNLIKFNSWIKDTMTKNS", "length": 261 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P07647-1", "protein_name": "Submandibular glandular kallikrein-9", "gene_name": "Klk9", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MWFLILFLALSLGQIDAAPPGQSRVVGGYNCETNSQPWQVAVIGTTFCGGVLIDPSWVITAAHCYSKNYRVLLGRNNLVKDEPFAQRRLVSQSFQHPDYIPVFMRNHTRQRAYDHNNDLMLLHLSKPADITGGVKVIDLPTEEPKVGSICLASGWGMTNPSEMKLSHDLQCVNIHLLSNEKCIETYKNIETDVTLCAGEMDGGKDTCTGDSGGPLICDGVLQGLTSGGATPCAKPKTPAIYAKLIKFTSWIKKVMKENP", "length": 259 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P08932-1", "protein_name": "T-kininogen 2", "gene_name": "", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKLITILLLCSRLLPSLAQEEGAQEMDCNDETVFQAVDTALKKYNAELESGNQFLLYRVTEGTKKDGAETLYSFKYQIKEGNCSVQSGLTWQDCDFKDAEEAATGECTTTLGKKENKFSVATQICNITPGKGPKKTEEDLCVGCFQPIPMDSSDLKPVLKHAVEHFNNNTKHTHLFALTEVKSAHSQVVAGMNYKIIYSIVQTNCSKEDFPFLREDCVPLPYGDHGECRGHTYVDIHNTIAGFSQSCDLYPGDDLFSLLPKKCFGCPKNIPVDSPELKEALGHSIAQLNAQHNHLFYFKIDTVKKATSQVVAGTKYVIEFIARETNCSKQTNTELTADCETKHLGQSLNCNANVYMRPWENKVVPTVRCQALDMMISRPPGFSPFRLVQVQETKEGTTRLLNSCEYKGRLSKAGAGPAPDHQAEASTVTP", "length": 430 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P0C0S7-1", "protein_name": "Histone H2A.Z", "gene_name": "H2az1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAGGKAGKDSGKAKTKAVSRSQRAGLQFPVGRIHRHLKSRTTSHGRVGATAAVYSAAILEYLTAEVLELAGNASKDLKVKRITPRHLQLAIRGDEELDSLIKATIAGGGVIPHIHKSLIGKKGQQKTV", "length": 128 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P0C2B7-1", "protein_name": "Large ribosomal subunit protein mL52", "gene_name": "MRPL52", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAALGMLLSTGVRRLHCGSAARAGSQWRLRQGLAANPSGYGPLTELPDWSYADGRPAPPMKGQLRRKAQREKFARRVVLLSQEMDAGLQAWQLRQQEKLQEEKRKQQNALKPKGVLLQNPGPSQ", "length": 124 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P0C644-1", "protein_name": "Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1", "gene_name": "Ppip5k1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MWSLTANEDEDESATAHFFLGAGDEGLGTCGIGMRTGESDSELLEDEEDEVPPEPQIIVGICAMTKKSKSKPMTQILERLCRFDYLTVVILGEDVILNEPVENWPPCHCLISFHSKGFPLDKAVAYSKLRNPFLINDLTMQYYIQDRREVYRILQEEGIDLPRYAVLNRDPACPEECNLIEGEDQVEVNGAVFPKPFVEKPVSAEDHNVYIYYPSSAGGGSQRLFRKIGSRSSVYSPESSVRKTGSYIYEEFMPTDGTDVKVYTVGPDYAHAEARKSPALDGKVERDSEGKEVRYPVMLTAMEKLVARKVCVAFKQTVCGFDLLRANGHSFVCDVNGFSFVKNSMKYYDDCAKILGNTIMRELAPQFQIPWSIPTEAEDIPIVPTTSGTMMELRCVIAIIRHGDRTPKQKMKMEVTHPRFFALFEKHGGYKTGKLKLKRPEQLQEVLDITRLLLAELEKEPGAEIEEKTGKLEQLKSVLEMYGHFSGINRKVQLTYYPHGVKASSEGQDLQREPPAPSLLLVLKWGGELTPDGRVQAEELGRAFRCMYPGGQGDYAGFPGCGLLRLHSTFRHDLKIYASDEGRVQMTAAAFAKGLLALEGELTPILVQMVKSANMNGLLDSDSDSLSSCQHRVKARLHHILQQDAPFGPEDYDQLAPTGSTSLLNSMSVIQNPVKVCDQVFALIENLTHQIRERMQDPSSVDLQLYHSETLELMLQRWSKLERDFRQKSGRYDISKIPDIYDCVKYDVQHNGSLGLQGTAELLRLSKALADVVIPQEYGISREEKVEIAVGFCLPLLRKILLDLQRTHEDESVNKLHPLYSRGVLSPGRHVRTRLYFTSESHVHSLLSVFRYGGLLDETKDAQWQRALAYLSAISELNYMTQIVIMLYEDNTRDPLSEERFHVELHFSPGVKGVEEGSAPAGCGFRPASSENEEMKTDPGSIENLCPAKPSDEPDRALQTSPQPVEGTGLPRRSPLIRNRKAGSMEVLSETSSSRPGGYRLFSSSRPPTEMKQSGLGSQCTGLFSTTVLGGSSSAPNLQDYARTHGKKLPPAGLKHRDELLFVPAVKRFSVSFAKHPTNGFEGCSMVPTIYPLETLHNALSLRQVSEFLTKVCQRHTDAHAQASAALFDSMHNHQASDNPFSPPRTLHSPPLQLRHRSEKPPWYSSGPSSTVSSAGPSSPTTVDGNSHFGFSDQSSVNTQMIEEKQGLGLLQETPGDGTPEFHIELAESTQSPQEPPVEISPPGSQDDTEVNQTCQEVPDTIQPCHDILEEIGQPNQEVPDISQLLLKNHDTATNTCQPCQASQLSKKVYEEICQLCQDNPEESNQLCQEVSVELGRMVHRFPVSIGSTTQETLMEIGRPTQEIPEEPCQEFSEKVGMLTQKASAISELSQDILETDNPSQELSEETDLQAQEVSEEIDQEPEVVDELSNEDIS", "length": 1434 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P0C7H9-1", "protein_name": "Inactive ubiquitin carboxyl-terminal hydrolase 17-like protein 7", "gene_name": "USP17L7", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEDDSLYLGGDWQFNHFSKLTSSRLDAAFAEIQRTSLSEKSPLSSETRFDLCDDLAPVARQLAPREKLPLSSRRPAAVGAGLQKIGNTFYVNVSLQCLTYTLPLSNYMLSREDSQTCHLHKCCMFCTMQAHITWALHSPGHVIQPSQVLAAGFHRGEQEDAHEFLMFTVDAMKKACLPGHKQLDHHSKDTTLIHQIFGAYWRSQIKYLHCHGVSDTFDPYLDIALDIQAAQSVKQALEQLVKPKELNGENAYHCGLCLQKAPASKTLTLPTSAKVLILVLKRFSDVTGNKLAKNVQYPKCRDMQPYMSQQNTGPLVYVLYAVLVHAGWSCHNGHYFSYVKAQEGQWYKMDDAEVTASGITSVLSQQAYVLFYIQKSEWERHSESVSRGREPRALGAEDTDRPATQGELKRDHPCLQVPELDEHLVERATQESTLDHWKFPQEQNKTKPEFNVRKVEGTLPPNVLVIHQSKYKCGMKNHHPEQQSSLLNLSSTKPTDQESMNTGTLASLQGSTRRSKGNNKHSKRSLLVCQ", "length": 530 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0CW02-1", "protein_name": "Lymphocyte antigen 6C1", "gene_name": "Ly6c1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDTSHTTKSCVLILLVALLCAERAQGLQCYECYGVPIETSCPAVTCRASDGFCIAQNIELIEDSQRRKLKTRQCLSFCPAGVPIRDPNIRERTSCCSEDLCNAAVPTAGSTWTMAGVLLFSLSSVVLQTLL", "length": 131 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P0DKL4-1", "protein_name": "Spliceosome-associated protein 130 A", "gene_name": "SAP130A", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MYLYSLTLQQATGIVCAINGNFSGGKTQEIAVARGKILDLLRPDENGKIQTIHSVEVFGAIRSLAQFRLTGAQKDYIVVGSDSGRIVILEYNKEKNVFDKVHQETFGKSGCRRIVPGQYVAVDPKGRAVMIGACEKQKLVYVLNRDTTARLTISSPLEAHKSHTICYSLCGVDCGFDNPIFAAIELDYSEADQDPTGQAASEAQKHLTFYELDLGLNHVSRKWSNPVDNGANMLVTVPGGADGPSGVLVCAENFVIYMNQGHPDVRAVIPRRTDLPAERGVLVVSAAVHKQKTMFFFLIQTEYGDVFKVTLDHNGDHVSELKVKYFDTIPVASSICVLKLGFLFSASEFGNHGLYQFQAIGEEPDVESSSSNLMETEEGFQPVFFQPRRLKNLVRIDQVESLMPLMDMKVLNIFEEETPQIFSLCGRGPRSSLRILRPGLAITEMAVSQLPGQPSAVWTVKKNVSDEFDAYIVVSFTNATLVLSIGEQVEEVNDSGFLDTTPSLAVSLIGDDSLMQVHPNGIRHIREDGRINEWRTPGKRSIVKVGYNRLQVVIALSGGELIYFEADMTGQLMEVEKHEMSGDVACLDIAPVPEGRKRSRFLAVGSYDNTVRILSLDPDDCLQILSVQSVSSAPESLLFLEVQASIGGDDGADHPANLFLNSGLQNGVLFRTVVDMVTGQLSDSRSRFLGLKPPKLFSISVRGRSAMLCLSSRPWLGYIHRGHFHLTPLSYETLEFAAPFSSDQCAEGVVSVAGDALRIFMIDRLGETFNETVVPLRYTPRKFVLHPKRKLLVIIESDQGAFTAEEREAARKECFEAGGVGENGNGNADQMENGADDEDKEDPLSDEQYGYPKAESEKWVSCIRVLDPKTATTTCLLELQDNEAAYSVCTVNFHDKEYGTLLAVGTVKGMQFWPKKNLVAGFIHIYRFVEDGKSLELLHKTQVEGVPLALCQFQGRLLAGIGPVLRLYDLGKKRLLRKCENKLFPNTIISIQTYRDRIYVGDIQESFHYCKYRRDENQLYIFADDCVPRWLTASHHVDFDTMAGADKFGNVYFVRLPQDLSEEIEEDPTGGKIKWEQGKLNGAPNKVDEIVQFHVGDVVTCLQKASMIPGGSESIMYGTVMGSIGALHAFTSRDDVDFFSHLEMHMRQEYPPLCGRDHMAYRSAYFPVKDVIDGDLCEQFPTLPMDLQRKIADELDRTPAEILKKLEDARNKII", "length": 1214 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "P0DKL6-1", "protein_name": "Spliceosome-associated protein 130 B", "gene_name": "SAP130B", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MYLYSLTLQQATGIVCAINGNFSGGKTQEIAVARGKILDLLRPDENGKIQTIHSVEVFGAIRSLAQFRLTGAQKDYIVVGSDSGRIVILEYNKEKNVFDKVHQETFGKSGCRRIVPGQYVAVDPKGRAVMIGACEKQKLVYVLNRDTTARLTISSPLEAHKSHTICYSLCGVDCGFDNPIFAAIELDYSEADQDPTGQAASEAQKHLTFYELDLGLNHVSRKWSNPVDNGANMLVTVPGGADGPSGVLVCAENFVIYMNQGHPDVRAVIPRRTDLPAERGVLVVSAAVHKQKTMFFFLIQTEYGDVFKVTLDHNGDHVSELKVKYFDTIPVASSICVLKLGFLFSASEFGNHGLYQFQAIGEEPDVESSSSNLMETEEGFQPVFFQPRRLKNLVRIDQVESLMPLMDMKVLNIFEEETPQIFSLCGRGPRSSLRILRPGLAITEMAVSQLPGQPSAVWTVKKNVSDEFDAYIVVSFTNATLVLSIGEQVEEVNDSGFLDTTPSLAVSLIGDDSLMQVHPNGIRHIREDGRINEWRTPGKRSIVKVGYNRLQVVIALSGGELIYFEADMTGQLMEVEKHEMSGDVACLDIAPVPEGRKRSRFLAVGSYDNTVRILSLDPDDCLQILSVQSVSSAPESLLFLEVQASIGGDDGADHPANLFLNSGLQNGVLFRTVVDMVTGQLSDSRSRFLGLKPPKLFSISVRGRSAMLCLSSRPWLGYIHRGHFHLTPLSYETLEFAAPFSSDQCAEGVVSVAGDALRIFMIDRLGETFNETVVPLRYTPRKFVLHPKRKLLVIIESDQGAFTAEEREAARKECFEAGGVGENGNGNADQMENGADDEDKEDPLSDEQYGYPKAESEKWVSCIRVLDPKTATTTCLLELQDNEAAYSVCTVNFHDKEYGTLLAVGTVKGMQFWPKKNLVAGFIHIYRFVEDGKSLELLHKTQVEGVPLALCQFQGRLLAGIGPVLRLYDLGKKRLLRKCENKLFPNTIISIQTYRDRIYVGDIQESFHYCKYRRDENQLYIFADDCVPRWLTASHHVDFDTMAGADKFGNVYFVRLPQDLSEEIEEDPTGGKIKWEQGKLNGAPNKVDEIVQFHVGDVVTCLQKASMIPGGSESIMYGTVMGSIGALHAFTSRDDVDFFSHLEMHMRQEYPPLCGRDHMAYRSAYFPVKDVIDGDLCEQFPTLPMDLQRKIADELDRTPAEILKKLEDARNKII", "length": 1214 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "P0DML3-1", "protein_name": "Chorionic somatomammotropin hormone 2", "gene_name": "CSH2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAGSRTSLLLAFALLCLPWLQEAGAVQTVPLSRLFDHAMLQAHRAHQLAIDTYQEFEETYIPKDQKYSFLHDSQTSFCFSDSIPTPSNMEETQQKSNLELLRISLLLIESWLEPVRFLRSMFANNLVYDTSDSDDYHLLKDLEEGIQTLMGRLEDGSRRTGQILKQTYSKFDTNSHNHDALLKNYGLLYCFRKDMDKVETFLRMVQCRSVEGSCGF", "length": 217 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0DMV2-1", "protein_name": "Cancer/testis antigen family 45 member A9", "gene_name": "CT45A9", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTDKTEKVAVDPETVFKRPRECDSPSYQKRQRMALLARKQGAGDSLIAGSAMSKEKKLMTGHAIPPSQLDSQIDDFTGFSKDRMMQKPGSNAPVGGNVTSSFSGDDLECRETAFSPKSQQEINADIKRQLVKELRCVGQKYEKIFEMLEGVQGPTAVRKRFFESIIKEAARCMRRDFVKHLKKKLKRMI", "length": 189 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0DOV1-1", "protein_name": "Interferon-activable protein 211", "gene_name": "Ifi211", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVNEYKRIVLLRGLECINKHYFSLFKSLLARDLNLERDNQEQYTTIQIANMMEEKFPADSGLGKLIEFCEEVPALRKRAEILKKERSEVTGETSLEKNGQEAGPATPTSTTSHMLASERGETSATQEETSTAQAGTSTAQAGTSTAQAGTSTAQKRKSMREEETGVKKSKAAKEPDQPPCCEEPTAMCQSPILHSSSSASSNILSAKNQKSQPQNQNIPRGAVLHSEPLTVMVLTATDPFEYESPEHEVKNMFHATVATVSQYFHVKVFNIDLKEKFTKNNFITISNYFESKGILEINETSSVLEAAPKQMIEVPNCITRNANASPKICDIQKGTSGTVFYGVFTLHKKKVKTQNTSYEIKDGSGSIEVVGSGQWHNINCKEGDKLHLFCFHLKRERGQPKLVCGDHSFVKVTKAGKKKEASTVQ", "length": 425 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P0DTA3-1", "protein_name": "Speedy protein E11", "gene_name": "SPDYE11", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGQILGKIMMSHQPQPQEERSPQRSTSGYPLQEVVDDEVSGPSAPGVDPSPPRRSLGWKRKRECLDESDDEPEKELAPEPEETWVAETLCGLKMKAKRRRVSLVLPEYYEAFNRLLEDPVIKRLLAWDKDLRVSDKYLLAMVIAYFSRAGLPSWQYQRIHFFLALYLANDMEEDDEAPKQNIFYFLYEETRSHIPLLSELWFQLCRYMNPRARKNCSQIALFRKYRFHFFCSMRCRAWVSLEELEEIQAYDPEHWVWARDRAHLS", "length": 265 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0DUD3-1", "protein_name": "Speedy protein E14", "gene_name": "SPDYE14", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGQILGKIMMSHQPQPQEERSPQRSTSGYPLQEVVDDEVLGPSAPGVDPSPPRRSLGWKRKRECLDESDDEPEKELAPEPEETWVAETLCGLKMKAKRRRVSLVLPEYYEAFNRLLEDPVIKRLLAWDKDLRVSDKYLLAMVIAYFSRAGLPSWQYQRIHFFLALYLANDMEEDDEAPKQNIFYFLYEETRSHIPLLSELWFQLCRYMNPRARKNCSQIALFRKYRFHFFCSMRCRAWVSLEELEEIQAYDPEHWVWARDRAHLS", "length": 265 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0DUD4-1", "protein_name": "Speedy protein E15", "gene_name": "SPDYE15", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGQILGKIMMSHQPQPQEERSPQRSTSGYPLQEVVDDEVLGPSAPGVDPSPPRRSLGWKRKRECLDESDDEPEKELAPEPEETWVAETLCGLKMKAKRRRVSLVLPEYYEAFNRLLEDPVIKRLLAWDKDLRVSDKYLLAMVIAYFSRAGLPSWQYQRIHFFLALYLANDMEEDDEAPKQNIFYFLYEETRSHIPLLSELWFQLCRYMNPRARKNCSQIALFRKYRFHFFCSMRCRAWVSLEELEEIQAYDPEHWVWARDRAHLS", "length": 265 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0DW11-1", "protein_name": "TATA-box-binding protein-associated factor 11-like protein 6", "gene_name": "TAF11L6", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "METGRQTGVSAEMLAMPRGLKGSKKDGIPEDLDGNLEAPRDQEGELRSEDVMDLTEGDSEASASAPPAAKRRKTHTKGKKESKPTVDAEEAQRMTTLLSAMSEEQLSRYEVCRRSAFPRARVAGLMRAITGSSVSENAAIAMAGIAKLFVGEVVEEALDVCEMWGETPPLQPKHLREAVRRLKPKGLFPNSNCKRIMF", "length": 198 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0DW12-1", "protein_name": "TATA-box-binding protein-associated factor 11-like protein 7", "gene_name": "TAF11L7", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "METGRQTGVSAEMLAMPRGLKGSKKDGIPEDLDGNLEAPRDQEGELRSEDVMDLTEGDSEASASAPPAAKRRKTHTKGKKESKPTVDAEEAQRMTTLLSAMSEEQLSRYEVCRRSAFPRARVAGLMRAITGSSVSENAAIAMAGIAKLFVGEVVEEALDVCEMWGETPPLQPKHLREAVRRLKPKGLFPNSNCKRIMF", "length": 198 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0DW13-1", "protein_name": "TATA-box-binding protein-associated factor 11-like protein 8", "gene_name": "TAF11L8", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "METGRQTGVSAEMLAMPRGLKGSKKDGIPEDLDGNLEAPRDQEGELRSEDVMDLTEGDSEASASAPPAAKRRKTHTKGKKESKPTVDAEEAQRMTTLLSAMSEEQLSRYEVCRRSAFPRARVAGLMRAITGSSVSENAAIAMAGIAKLFVGEVVEEALDVCEMWGETPPLQPKHLREAVRRLKPKGLFPNSNCKRIMF", "length": 198 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0DW14-1", "protein_name": "TATA-box-binding protein-associated factor 11-like protein 10", "gene_name": "TAF11L10", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "METGRQTGVSAEMLAMPRGLKGSKKDGIPEDLDGNLEAPRDQEGELRSEDVMDLTEGDSEASASAPPAAKRRKTHTKGKKESKPTVDAEEAQRMTTLLSAMSEEQLSRYEVCRRSAFPRARVAGLMRAITGSSVSENAAIAMAGIAKLFVGEVVEEALDVCEMWGETPPLQPKHLREAVRRLKPKGLFPNSNCKRIMF", "length": 198 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P11588-1", "protein_name": "Major urinary protein 1", "gene_name": "Mup1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKMLLLLCLGLTLVCVHAEEASSTGRNFNVEKINGEWHTIILASDKREKIEDNGNFRLFLEQIHVLENSLVLKFHTVRDEECSELSMVADKTEKAGEYSVTYDGFNTFTIPKTDYDNFLMAHLINEKDGETFQLMGLYGREPDLSSDIKERFAQLCEKHGILRENIIDLSNANRCLQARE", "length": 180 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P11589-1", "protein_name": "Major urinary protein 2", "gene_name": "Mup2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKMLLLLCLGLTLVCVHAEEASSTGRNFNVEKINGEWHTIILASDKREKIEDNGNFRLFLEQIHVLEKSLVLKFHTVRDEECSELSMVADKTEKAGEYSVTYDGFNTFTIPKTDYDNFLMAHLINEKDGETFQLMGLYGREPDLSSDIKERFAKLCEEHGILRENIIDLSNANRCLQARE", "length": 180 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P13255-1", "protein_name": "Glycine N-methyltransferase", "gene_name": "Gnmt", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVDSVYRTRSLGVAAEGIPDQYADGEAARVWQLYIGDTRSRTAEYKAWLLGLLRQHGCHRVLDVACGTGVDSIMLVEEGFSVTSVDASDKMLKYALKERWNRRKEPAFDKWVIEEANWLTLDKDVPAGDGFDAVICLGNSFAHLPDSKGDQSEHRLALKNIASMVRPGGLLVIDHRNYDYILSTGCAPPGKNIYYKSDLTKDITTSVLTVNNKAHMVTLDYTVQVPGAGRDGAPGFSKFRLSYYPHCLASFTELVQEAFGGRCQHSVLGDFKPYRPGQAYVPCYFIHVLKKTG", "length": 293 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P13675-1", "protein_name": "Y-linked testis-specific protein 1", "gene_name": "Ssty1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSLMKKRRRKSSSNTLRNIVSCRISHSWKEGNEPVTQWKAIVLDQLPTNPSLYFVKYDGIDSIYVLELYSDDRILNLKVLPPIVVFPQVRDAHLARALVGRAVQHKFERKDGSEVNWRGVVLAQVPIMKDLFYITYKKDPALYAYQLLDDYKEGNLHMIPDTPPAEERSGDDSDVLIGNWVEYTRKDGSKKFGKVVYQVLANPSVYFIKFHGDIHIYVYTMVPKILEVEKS", "length": 232 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P15515-1", "protein_name": "Histatin-1", "gene_name": "HTN1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKFFVFALVLALMISMISADSHEKRHHGYRRKFHEKHHSHREFPFYGDYGSNYLYDN", "length": 57 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P16374-1", "protein_name": "Zinc finger protein 60", "gene_name": "Zfp60", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MANSSSQHMVCGSVTFRDVAVDFSQEEWACLDATQKVLYRNIMLETYSNLVAVVGRCIPKPDLIVLLEPEKEPWMAVKKETGRPSQGLETGFEAENRSPKNHVYNKKLPKQTIQQLSKTSDVQGVSVSNGPGYSVIKEPQNYQEGDANRNITNKKEMSTYTSKTLAHNKEKPYKCKDCGKCFGCKSNLHQHESIHTGEKPYECKDCGKTFRLPQMLSRHQKSHSDERPFECNICGKSFHLPTLLQYHKNIHTGLKPFECEECGKSFKSFNRISTLFQHRTIHAGMKPYKCNVCGKAFNRRSNLLQHQKIHSEDRPFHCKVCGKAFTVLAQLTRHENIHTEDKSFECKQCGKIFSNGSYLLRHYDTHTNEKPFECNICGKAFRLHLYLSEHQKTHTDEKPFKCKLCESAFRRKYQLSEHQRIHTDGKPYQCKDCWEFFRRRSNFIEHQSIHTGKKPFECKDCGKVFRLNIHLIRHQRFHSDEKPFECKECGKAFHFSSQLNNHKTSHTGQTPFECKECGKSFKRVSSLVEHRIIHSGVKPYKCNACGRAFNRRSNLMQHEKIHSDERPFECKDCGKAFTVLAQLTRHQTIHNGKKSYECEQCGSAFRLPYQLTQHQRIHYDVKPFQCKECGRAFVRSTGLRIHERIHTGEKPFQCKECGEAFQYHYQFLGHFRIHTGKNPYECSECGKYFTYGRDLKVHQSIHNLEKP", "length": 707 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P20816-1", "protein_name": "Cytochrome P450 4A2", "gene_name": "Cyp4a2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGFSVFSPTRSLDGVSGFFQGAFLLSLFLVLFKAVQFYLRRQWLLKALEKFPSTPSHWLWGHNLKDREFQQVLTWVEKFPGACLQWLSGSTARVLLYDPDYVKVVLGRSDPKPYQSLAPWIGYGLLLLNGKKWFQHRRMLTPAFHYDILKPYVKIMADSVSIMLDKWEKLDDQDHPLEIFHYVSLMTLDTVMKCAFSHQGSVQLDVNSRSYTKAVEDLNNLIFFRVRSAFYGNSIIYNMSSDGRLSRRACQIAHEHTDGVIKTRKAQLQNEEELQKARKKRHLDFLDILLFAKMEDGKSLSDEDLRAEVDTFMFEGHDTTASGISWVFYALATHPEHQERCREEVQSILGDGTSVTWDHLDQMPYTTMCIKEALRLYSPVPSVSRELSSPVTFPDGRSIPKGIRVTILIYGLHHNPSYWPNPKVFDPSRFSPDSPRHSHAYLPFSGGARNCIGKQFAMNELKVAVALTLLRFELLPDPTRIPVPMPRLVLKSKNGIHLRLKKLR", "length": 504 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P21571-1", "protein_name": "ATP synthase peripheral stalk subunit F6, mitochondrial", "gene_name": "Atp5pf", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTVQRIFRLSSVLRSAVSVHLRRNIGVTAVAFNKELDPVQKLFLDKIREYKAKRLASGGPVDTGPEYQQEVDRELFKLKQMYGKGEMDKFPTFNFEDPKFEVLDKPQS", "length": 108 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P22237-1", "protein_name": "NADH-ubiquinone oxidoreductase subunit 9", "gene_name": "nad9", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKDYKNELKVKINLGEHLRLSIPGLVKKIMYKTHYLEIQVEKEKMLTVLKYLKEASKYQCNMLLDIVCVDCLNIEEIKIGRFKLIYVLNSIYNNTRVHLSTYVENNGIIETTSGLFESSVWLEREIWDMFGIYFEKHPDLRRILTDYGFVGYPLKKDFPITGYLEVYYDVNDKKIIYKPIELMQEYRNYNFGAVWGDYERKVYLENIIK", "length": 209 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "P22283-1", "protein_name": "Cystatin-related protein 2", "gene_name": "Crp2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MYKTLCGTQLLLAIFVLFLNFSHATAKGTRGPMEIFKKNFMEKNKLNDVYDIFKFLYNKFSHDTYLSNIKNQSFTMNTWGFGEIEVVKTKCRKIDSDFYKCSFQWEFCNIKRTPGVTIYYITLPGSVRCRKLLSKLVNCPFEEQTEQLKREICYFQLYPDYIEQNIRSVRFNCYTK", "length": 176 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P23266-1", "protein_name": "Olfactory receptor 1f45", "gene_name": "Or1f45", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSSTNQSSVTEFLLLGLSRQPQQQQLLFLLFLIMYLATVLGNLLIILAIGTDSRLHTPMYFFLSNLSFVDVCFSSTTVPKVLANHILGSQAISFSGCLTQLYFLAVFGNMDNFLLAVMSYDRFVAICHPLHYTTKMTRQLCVLLVVGSWVVANMNCLLHILLMARLSFCADNMIPHFFCDGTPLLKLSCSDTHLNELMILTEGAVVMVTPFVCILISYIHITCAVLRVSSPRGGWKSFSTCGSHLAVVCLFYGTVIAVYFNPSSSHLAGRDMAAAVMYAVVTPMLNPFIYSLRNSDMKAALRKVLAMRFPSKQ", "length": 313 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P24049-1", "protein_name": "Large ribosomal subunit protein uL22", "gene_name": "Rpl17", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVRYSLDPENPTKSCKSRGSNLRVHFKNTRETAQAIKGMHIRKATKYLKDVTLKKQCVPFRRYNGGVGRCAQAKQWGWTQGRWPKKSAEFLLHMLKNAESNAELKGLDVDSLVIEHIQVNKAPKMRRRTYRAHGRINPYMSSPCHIEMILTEKEQIVPKPEEEVAQKKKISQKKLKKQKLMARE", "length": 184 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P24868-1", "protein_name": "G2/mitotic-specific cyclin-1", "gene_name": "CLB1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSRSLLVENSRTINSNEEKGVNESQYILQKRNVPRTILGNVTNNANILQEISMNRKIGMKNFSKLNNFFPLKDDVSRADDFTSSFNDSRQGVKQEVLNNKENIPEYGYSEQEKQQCSNDDSFHTNSTALSCNRLIYSENKSISTQMEWQKKIMREDSKKKRPISTLVEQDDQKKFKLHELTTEEEVLEEYEWDDLDEEDCDDPLMVSEEVNDIFDYLHHLEIITLPNKANLYKHKNIKQNRDILVNWIIKIHNKFGLLPETLYLAINIMDRFLCEEVVQLNRLQLVGTSCLFIASKYEEIYSPSIKHFAYETDGACSVEDIKEGERFILEKLDFQISFANPMNFLRRISKADDYDIQSRTLAKFLMEISIVDFKFIGILPSLCASAAMFLSRKMLGKGTWDGNLIHYSGGYTKAKLYPVCQLLMDYLVGSTIHDEFLKKYQSRRFLKASIISIEWALKVRKNGYDIMTLHE", "length": 471 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P25389-1", "protein_name": "Probable serine/threonine-protein kinase KCC4", "gene_name": "KCC4", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MTVANTETHSAAKPSSTIGPWKLGETLGFGSTGKVQLAQHERTGHRTAVKVISKSIFNNNGNHSNDDSVLPYNIEREIVIMKLLSHPNVLSLYDVWETNNNLYLILEYAEKGELFNLLVDHGPLPEREAINCFRQIIIGISYCHALGIVHRDLKPENLLLDSFYNIKIADFGMAALQTDADLLETSCGSPHYAAPEIVSGLPYEGFASDVWSCGVILFALLTGRLPFDEENGNVRDLLLKVQKGQFEMPNDTEISRDAQDLIGKILVVDPRQRIKIRDILSHPLLKKYQTIKDSKSIKDLPRENTYLYPLADSNNHTSASIDDSILQNLVVLWHGRHADDIVSKLKENGTNKEKILYALLYRFKLDSVRGSNKKNRNKIKKTKKNKRSSTLSSSSSLLLNNRSIQSTPRRRTSKRHSREFSSSRKRSSFLLSSNPTDSSPIPLRSSKRITHINVASANTQATPSGVPNPHKRNSKKRSSKRLSYMPNTKRSSLTSKSLSNFTNLIDDDDWEYIEKDAKRTSSNFATLIDEIFEPEKFELAKREKAELQRKVQEAKRQSVNAQKINEDEFGSEVSDGMKELKKINDKVSSPLINYEFSQQELLQDIDTLLTNRYQLSSYTRPISRLDPGLTPVTETLPNNLKEKTALLQDTEKKIIETIRRSKFLGSLLNVRGGLSPGKSELAPIEESPIVSTTPLIYNDRMEPRRISDVEVPHFTRKSKHFTTANNRRSVLSLYAKDSIKDLNEFLIKEDPDLPPQGSTDNESRSEDPEIAESITDSRNIQYDEDDSKDGDNVNNDNILSDFPQGVGISQEYDMKDKNPNQSPISKSAEPTLVVKLPSLSSFQGKNASGLGLYQREPSKVTLPSLTSNNSSVGENIEDGAEKGTESEKIAASLSDDDLKEDNDKKDNDTVNAPTTVKKPPNSVLLKKFSKGKILELEIHAKIPEKRLYEGLHKLLEGWKQYGLKNLVFNITNMIITGKLVNDSILFLRSTLFEIMVLPNGDGRSLIKFNKKTGSTKTLTKLATEIQIILQKEGVLDK", "length": 1037 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P28312-1", "protein_name": "Alpha-defensin 5", "gene_name": "Defa5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKTFVLLSALVLLAFQVQADPIHKTDEETNTEEQPGEEDQAVSISFGGQEGSALHEELSKKLICYCRIRGCKRRERVFGTCRNLFLTFVFCCS", "length": 93 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P28742-1", "protein_name": "Kinesin-like protein KIP1", "gene_name": "KIP1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MARSSLPNRRTAQFEANKRRTIAHAPSPSLSNGMHTLTPPTCNNGAATSDSNIHVYVRCRSRNKREIEEKSSVVISTLGPQGKEIILSNGSHQSYSSSKKTYQFDQVFGAESDQETVFNATAKNYIKEMLHGYNCTIFAYGQTGTGKTYTMSGDINILGDVQSTDNLLLGEHAGIIPRVLVDLFKELSSLNKEYSVKISFLELYNENLKDLLSDSEDDDPAVNDPKRQIRIFDNNNNNSSIMVKGMQEIFINSAHEGLNLLMQGSLKRKVAATKCNDLSSRSHTVFTITTNIVEQDSKDHGQNKNFVKIGKLNLVDLAGSENINRSGAENKRAQEAGLINKSLLTLGRVINALVDHSNHIPYRESKLTRLLQDSLGGMTKTCIIATISPAKISMEETASTLEYATRAKSIKNTPQVNQSLSKDTCLKDYIQEIEKLRNDLKNSRNKQGIFITQDQLDLYESNSILIDEQNLKIHNLREQIKKFKENYLNQLDINNLLQSEKEKLIAIIQNFNVDFSNFYSEIQKIHHTNLELMNEVIQQRDFSLENSQKQYNTNQNMQLKISQQVLQTLNTLQGSLNNYNSKCSEVIKGVTEELTRNVNTHKAKHDSTLKSLLNITTNLLMNQMNELVRSISTSLEIFQSDSTSHYRKDLNEIYQSHQQFLKNLQNDIKSCLDSIGSSILTSINEISQNCTTNLNSMNVLIENQQSGSSKLIKEQDLEIKKLKNDLINERRISNQFNQQLAEMKRYFQDHVSRTRSEFHDELNKCIDNLKDKQSKLDQDIWQKTASIFNETDIVVNKIHSDSIASLAHNAENTLKTVSQNNESFTNDLISLSRGMNMDISSKLRSLPINEFLNKISQTICETCGDDNTIASNPVLTSIKKFQNIICSDIALTNEKIMSLIDEIQSQIETISNENNINLIAINENFNSLCNFILTDYDENIMQISKTQDEVLSEHCEKLQSLKILGMDIFTAHSIEKPLHEHTRPEASVIKALPLLDYPKQFQIYRDAENKSKDDTSNSRTCIPNLSTNENFPLSQFSPKTPVPVPDQPLPKVLIPKSINSAKSNRSKTLPNTEGTGRESQNNLKRRFTTEPILKGEETENNDILQNKKLHQ", "length": 1111 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P29314-1", "protein_name": "Small ribosomal subunit protein uS4", "gene_name": "Rps9", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPVARSWVCRKTYVTPRRPFEKSRLDQELKLIGEYGLRNKREVWRVKFTLAKIRKAARELLTLDEKDPRRLFEGNALLRRLVRIGVLDEGKMKLDYILGLKIEDFLERRLQTQVFKLGLAKSIHHARVLIRQRHIRVRKQVVNIPSFIVRLDSQKHIDFSLRSPYGGGRPGRVKRKNAKKGQGGAGAGDDEEED", "length": 194 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P33579-1", "protein_name": "Prolactin-8A5", "gene_name": "Prl8a5", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MELALSQPSFFGTLLMLVVSNLLLWEKAASIPACMVEDGGCWDPLREAFNSATQRAETLRNLSDQLYVEFFQNQFSSRQFADLSSQLIRKDETVLKAGTYCHSNRAKPKSRGVNIDIEEYLKMSINFCGFMDQPLFHLVIELSAMEGVPETILSKAKDLEENNRQLLDDLRWILTKVFPTAEIKEEFPSWDYLSFLKSSNKNHKFLAIFNLSSCLDYDTQVHYTLSQILNCLITGKDC", "length": 238 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P36006-1", "protein_name": "Myosin-3", "gene_name": "MYO3", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MAVIKKGARRKDVKEPKKRSAKIKKATFDANKKKEVGISDLTLLSKISDESINENLKKRFKNGIIYTYIGHVLISVNPFRDLGIYTNAVLESYKGKNRLEVPPHVFAIAESMYYNLKSYNENQCVIISGESGAGKTEAAKRIMQYIAAASNSHSESIGKIKDMVLATNPLLESFGCAKTLRNNNSSRHGKYLEIKFNSQFEPCAGNITNYLLEKQRVVGQIKNERNFHIFYQFTKGASDTYKQMFGVQMPEQYIYTAAAGCTTADTIDDVKDYEGTLEAMRTIGLVQEEQDQIFRMLAAILWIGNISFIENEEGNAQVGDTSVTDFVAYLLQVDASLLVKCLVERIMQTSHGMKRGSVYHVPLNPVQATAVRDALAKAIYNNLFDWIVDRVNVSLQAFPGADKSIGILDIYGFEIFEHNSFEQICINYVNEKLQQIFIQLTLKAEQETYEREKIKWTPIKYFDNKVVCDLIEAKNPPGILAAMNDSIATAHADSNAADQAFAQRLNLFNSNPYFELRANKFVIKHYAGDVTYDINGITDKNKDQLQKDLIELIGTTTNTFLSTIFPDDVDKDSKRRPPTAGDKIIKSANELVETLSKAEPSYIRTIKPNQTKSPNDYDDHQVLHQVKYLGLQENVRIRRAGFAYRQTFEKFVERFYLLSPDCSYAGDYTWDGDTLEAVKLILRDAMIPEKEFQLGVTSVFIKTPESLFALEDMRDKYWYNMAARIQRAWRRFLQRRIDAAIKIQRTIREKKGGNKYVKLRDYGTKLLAGKKERRSMSLLGYRAFMGDYLSCNESKTKGSYIRRQVGIKDKVVFSIKGECLHSKFGRSAQRLKKVFILTKKTFYIIGQTREQNAMKYTQDYKIDVGKIKQVSLTNLQDDWMGVILVNSTQSDPLINTPFKTELMTRLKKLNEKIMIKVGPTIEYHKQPNKLHTVRSKISDSAPKYGDIYKSSTIYVRRGHPANSKSNKKPKNPGGLSGKPIKSKKSKHKSTHKHTHSHRSHRDAAKKQPLPSQKPVNPLSLAATAAQAAYNPKPDKTVPIKSSAIPAAKVSSKHSSKPSSKEKVAVKKASSSHKSSSAKQNQVSMPPSKGVEKNKEPLKETTATATANIPIPPPPPPMGQPKDPKFEAAYDFPGSGSSSELPLKKGDIVFISRDEPSGWSLAKLLDGSKEGWVPTAYMTPYKDTRNTVPVAATGAVNDVTNQKSSQIDNTISSAQEGVQFGSATVGPTSDNQSNPVGTFSDGLASALAARANKMRAESADDDDNDDGDDDDDW", "length": 1272 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P36046-1", "protein_name": "Mitochondrial intermembrane space import and assembly protein 40", "gene_name": "MIA40", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MLRNLVVRNACRNRPSIQVARGLCRHQTRRLMASSPQFGRNSNQEKTAGFIMGILSMAGALYFIAPNRKPLFASRKVESDKTAEEELSSGGEQSPENEDDNNSKSDENGDDNDSKNDETEAGPQLGGDKIGASKVAEDGELVVLAEEDNKSSEDKDTDESKVSTKDDEQSNEDNATANNQKDENISSENSEENTSDKTLDNNAGSSEKKDPEHSDDEKSQQGQSDDKTTTEDNNGEEESSKKTVSDSENSAKQSESSDEEKEELRKQEEKQMGPTEEEVQHEGAYNPDTGEINWDCPCLGGMAHGPCGEEFKSAFSCFVYSEAEPKGIDCVEKFQHMQDCFRKYPEHYAEQLKETSDDEEPQDKVKVNTIESAPNVSSAKENAAKKAEQSDVKKEPLNEESKP", "length": 403 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P37106-1", "protein_name": "Signal recognition particle subunit SRP54 1", "gene_name": "SRP-54A", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MVLAELGGRITRAIQQMNNVTIIDEKVLNDFLNEITRALLQSDVSFGLVEKMQTNIKKIVNLDDLAAGHNKRLIIEQAIFKELCRMLDPGKPAFAPKKAKPSVVMFVGLQGAGKTTTCTKYAYYHQKKGYKAALVCADTFRAGAFDQLKQNATKAKIPFYGSYTESDPVKIAVEGVDRFKKEKCDLIIVDTSGRHKQAASLFEEMRQVAEATEPDLVIFVMDSSIGQAAFEQAEAFKETVSVGAVIITKMDGHAKGGGALSAVAATKSPVIFIGTGEHMDEFEVFDVKPFVSRLLGKGDWSGLVDKLQEVVPKDLQNELVENLSQGNFTLRSMYDQFQCSLRIPLNQLFSMLPGISAEMMPKGHGEESRVKMKRYMTMMDSMTNKELDSPNPKIFNESRIMRIARGSGRLVREVMEMLEEYKRIAKTMKGIKIPKNGDMSKVIPPQMLKQMGGMSGLQSLMKQMGSAKDMMGMFGGGGK", "length": 479 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "P38150-1", "protein_name": "Inactive deaminase YBR284W", "gene_name": "", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MVQNNESVFFVECDSYKESPSTSPIRLDDLDGNDAVSDQGLAFDGDVGITSQARVRNPRAQIFEDSNTDVVLHLDDLDMVPLNTKFDMQMEMGSPMAMPAETPPPVEPLKTKDLAYSSLAHLPSYFFEQTHFRIDRKCLLEMSKLRRNYLTISKQDALSCPQLHSRVAGGYLKPVKEKLFGIRHFLDLEESNTVNLLQDGNYMTELFNSQINIPTFKEFREDFEWCLKIIRDRSLSRFSEKRLQYLVNKFPVFQHLHSKEEMRQSKKVPHKDFYNCRKIDLNLLLSGCFSQWQLTEFIWTKLRKEPDRVIHQAFNGSHITLSQLFKVNFEETGQFFNGLKIIDDSFLEWYKVIYLAKYHLVNDEMEIHTGSHGKQLRYYLIAKTFLEFDNYINGEYLAELLKTFLIKPQEESKYQLCQLSVDFQFYLHYDNSDVDNWWMVFANWLNHYNIFSNNIRWNIRISRIYPELYHTGKVKNFQEYLNLIFKPLFNAENYLHKSLGPILLKFLSQVSSIDLCIQDTDNYIWKNFTAVSCLPKDWTSGGDNPTISQYMYYVYVNLTKLNHIRQALHQNTFTLRSSCSPTSMNRTSQFSNTLNFTEHTEAILNNFLLACGGFLNAENLWNAPPSLVYLFYLSQIPMVVAPLNSIVDSKPTMLQEQAPTGLVLEPSKPYKKNPFMKFFEMGFKISLSSESILYNNSYTKEPIIEEYSVAASIYRLHSADLCELLRNSVITSGFSSTLKNKWLGVSLASHDYFVENTGFVDKWYDCKPNTSLEHNVPIIRRQYRSSTLAGEWRLIIA", "length": 797 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P40002-1", "protein_name": "Transcriptional regulator MIT1", "gene_name": "MIT1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MDIEPTFKGYIEDEDDALLILQATLDGKLKHIPRRPYEIERPYLIVSGSIFVFIEEISGIKRWTDGVSWSPSRISGKFLIYKELDKENAGSNANATSSGSTDSAVITDGTSGARNNPSSSKIKLPPLKNHQFDLPPTMGHSSFESEQDTSISPSNRSNLPLKYTGLVKKTISVKLKRPPFNSIENLHIVSYYSVKDIKQNCLVTPKASPFLKDVRPSQELIVAMGNTTLGNVKNNSTTTGNGPNNINNKSNSSTPLNTVISTNNNSANINAAGSNQFTSANKNYYYKNDESSGYPITQFAPALPSTTLMYTANPPYITQSPDNTNATGMNTHVNNNNNNSNNSSNSNNSNNNNNNNNNNNNNNNNNINNINNVNTNAGNGNNPNRFHNASFAYNTTGDFINPQQQGQISYPFYYTTIPINNPNYYTTQPPNPVTNASTNENQGYSTSSTQHPYYGHPTESQSASAAAGATGTPGTAENVLPVSSMQPLLHQANNNSASSATSTAPYPVYSMNVNVPYYNSSASAYKRAQENTTSNTNAEPSGATSTNSGTMLSNPAYANSQYTPSQVYYQGFPQYAMASAQNPSMYQHQHQHPLPTVYPIATPQQNIMSSGHTLSTIGSDPQHHHYQQEPNDHKNFAMGHANNNILNITNNDTMNNLNTNTSTTTQ", "length": 666 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P42222-1", "protein_name": "Enolase-related protein 3", "gene_name": "ERR3", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSITKVHARTVYDSRGNPTVEVEITTENGLFRAIVPSGASTGIHEAVELRDGNKSEWMGKGVTKAVSNVNSIIGPALIKSDLCVTNQKGIDELMISLDGTSNKSRLGANAILGVSLCVARAAAAQKGITLYKYIAELADARQDPFVIPVPFFNVLNGGAHAGGSLAMQEFKIAPVGAQSFAEAMRMGSEVYHHLKILAKEQYGPSAGNVGDEGGVAPDIDTAEDALDMIVKAINICGYEGRVKVGIDSAPSVFYKDGKYDLNFKEPNSDPSHWLSPAQLAEYYHSLLKKYPIISLEDPYAEDDWSSWSAFLKTVNVQIIADDLTCTNKTRIARAIEEKCANTLLLKLNQIGTLTESIEAANQAFDAGWGVMISHRSGETEDPFIADLVVGLRCGQIKSGALSRSERLAKYNELLRIEEELGDDCIYAGHRFHDGNKL", "length": 437 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P43356-1", "protein_name": "Melanoma-associated antigen 2", "gene_name": "MAGEA2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPLEQRSQHCKPEEGLEARGEALGLVGAQAPATEEQQTASSSSTLVEVTLGEVPAADSPSPPHSPQGASSFSTTINYTLWRQSDEGSSNQEEEGPRMFPDLESEFQAAISRKMVELVHFLLLKYRAREPVTKAEMLESVLRNCQDFFPVIFSKASEYLQLVFGIEVVEVVPISHLYILVTCLGLSYDGLLGDNQVMPKTGLLIIVLAIIAIEGDCAPEEKIWEELSMLEVFEGREDSVFAHPRKLLMQDLVQENYLEYRQVPGSDPACYEFLWGPRALIETSYVKVLHHTLKIGGEPHISYPPLHERALREGEE", "length": 314 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P43357-1", "protein_name": "Melanoma-associated antigen 3", "gene_name": "MAGEA3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPLEQRSQHCKPEEGLEARGEALGLVGAQAPATEEQEAASSSSTLVEVTLGEVPAAESPDPPQSPQGASSLPTTMNYPLWSQSYEDSSNQEEEGPSTFPDLESEFQAALSRKVAELVHFLLLKYRAREPVTKAEMLGSVVGNWQYFFPVIFSKASSSLQLVFGIELMEVDPIGHLYIFATCLGLSYDGLLGDNQIMPKAGLLIIVLAIIAREGDCAPEEKIWEELSVLEVFEGREDSILGDPKKLLTQHFVQENYLEYRQVPGSDPACYEFLWGPRALVETSYVKVLHHMVKISGGPHISYPPLHEWVLREGEE", "length": 314 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P43537-1", "protein_name": "Uncharacterized membrane protein YFL067W", "gene_name": "", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MESIILSIAIFIGVLLGTSVGAGSGSSISPDVDAGSGSRTSPDVDAGSGSRISAGVGTFSGSSTSPDVDAGSGSSTSPDVGAGSGSSISAGVGSRIGTGIGSRIGTGIGTGIGSRISTSIGSRISPDVGTSSGNRISTGVSTGISTTMNARVAVLITAAILSAPVTAIALLEARR", "length": 175 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P46162-1", "protein_name": "Beta-defensin 4", "gene_name": "DEFB4", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MRLHHLLLAVLFLVLSAGSGFTQRVRNPQSCRWNMGVCIPFLCRVGMRQIGTCFGPRVPCCRR", "length": 63 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P46169-1", "protein_name": "Beta-defensin 11", "gene_name": "DEFB11", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MRLHHLLLALLFLVLSAGSGISGPLSCRRNGGVCIPIRCPGPMRQIGTCFGRPVKCCRSW", "length": 60 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P47102-1", "protein_name": "ARF guanine-nucleotide exchange factor 1", "gene_name": "GEA1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MHDVPMETVLAVNPATMIVKECINLCSAMNKQSRDKSQTSVAALLGGGSDIFLSQSDSFVDSFHNLPTSSYHDPLISGLVQLRLKINDLKGLDSLNALELLKPFLEIVSASSVSGYTTSLALDSLQKVFTLKIINKTFNDIQIAVRETVVALTHCRFEASKQISDDSVLLKVVTLLRDIITSSFGDYLSDTIIYDVLQTTLSLACNTQRSEVLRKTAEVTIAGITVKLFTKLKLLDPPTKTEKYINDESYTDNNLKDDIIGTTTSDNDLSSTDDDSAVADDNKNEKPVQQVIREQENDEETAEKAENVEPNYGITVIKDYLGLLLSLVMPENRMKHTTSAMKLSLQLINAAIEISGDKFPLYPRLFSLISDPIFKSVLFIIQSSTQYSLLQATLQLFTSLVVILGDYLPMQIELTLRRIFEILEDTTISGDVSKQKPPAIRELIIEQLSILWIHSPAFFLQLFVNFDCNLDRSDLSIDFIKELTKFSLPAAAVNTSNNIPPICLEGVLSLIENIYNDLQRFDRAEFVKNQKEIDILKQRDRKTEFILCVETFNEKAKKGIQMLIEKGFIDSDSNRDIASFLFLNNGRLNKKTIGLLLCDPKKTSLLKEFIDLFDFKGLRVDEAIRILLTKFRLPGESQQIERIVEAFSSKYSADQSNDKVELEDKKAGKNGSESMTEDDIIHVQPDADSVFVLSYSIIMLNTDSHNPQVKDHMTFDDYSNNLRGCYNGKDFPRWYLHKIYTSIKVKEIVMPEEHHGNERWFEDAWNNLISSTSVMTEMQRDFTNPISKLAQIDILQYEKAIFSNVRDIILKTLFKIFTVASSDQISLRILDAISKCTFINYYFSFDQSYNDTVLHLGEMTTLAQSSAKAVELDVDSIPLVEIFVEDTGSKISVSNQSIRLGQNFKAQLCTVLYFQIIKEISDPSIVSTRLWNQIVQLILKLFENLLMEPNLPFFTNFHSLLKLPELPLPDPDISIRKAKMSRSLLSTFASYLKGDEEPSEEDIDFSIKAFECVKASHPLSSVFENNQLVSPKMIETLLSSLVIEKTSENSPYFEQELLFLLEISIILISEASYGQEFGALIADHMINISNLDGLSKEAIARLASYKMFLVSRFDNPRDILSDLIEHDFLVKNEIFNTKYYESEWGKQVINDLFTHLNDVKYNERALKNVKFWNFLRILISAKDRQFAVYTFLEKYIQNGDIFVDDGNFMNILSLLDEMSCAGAVGTKWEQNYENSVEDGCEAPESNPYRSIIDLSSRSINITADLLSTVGRSNSALNKNEIIAAIQGLAHQCLNPCDELGMQALQALENILLSRASQLRTEKVAVDNLLETGLLPIFELDEIQDVKMKRITSILSVLSKIFLGQLVEGVTSNETFLRVLNVFNKYVDDPTVERQLQELIISKREIEKE", "length": 1408 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P53563-1", "protein_name": "Bcl-2-like protein 1", "gene_name": "Bcl2l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSQSNRELVVDFLSYKLSQKGYSWSQFSDVEENRTEAPEETEPERETPSAINGNPSWHLADSPAVNGATGHSSSLDAREVIPMAAVKQALREAGDEFELRYRRAFSDLTSQLHITPGTAYQSFEQVVNELFRDGVNWGRIVAFFSFGGALCVESVDKEMQVLVSRIASWMATYLNDHLEPWIQENGGWDTFVDLYGNNAAAESRKGQERFNRWFLTGMTVAGVVLLGSLFSRK", "length": 233 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P56840-1", "protein_name": "Protein TCL1B1", "gene_name": "Tcl1b1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAAAFDPLGPLPVYLVSVRLGIYEDEHHRVWIVANVETSHSSHGNRRRTHVTVHLWKLIPQQVIPFNPLNYDFLPTTWKLESRNIYWATDGTHWRLLDHSQLGDTEQLILMLVLG", "length": 116 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P56841-1", "protein_name": "Protein TCL1B2", "gene_name": "Tcl1b2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAAGFYPPRLLPQVLISTGPGFYEDEHHRLWMVAKLETCSHSPYCNKIETCVTVHLWQMTRYPQEPAPYNPMNYNFLPMTWRLASMNTYRGTDAMHWRLLNHSQVGDTVQLILMLE", "length": 117 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P56842-1", "protein_name": "Protein TCL1B3", "gene_name": "Tcl1b3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MADSVHFPWMPFPPRFLVCTRDDIYEDENGRQWVVAKVETSRSPYGSRIETCITVHLQHMTTIPQEPTPQQPINNNSLPTMWRLESMNTYTGTDGTYWRLLDHSQMGDTLQLILDIVICEVD", "length": 122 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P56844-1", "protein_name": "Protein TCL1B4", "gene_name": "Tcl1b4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MADSVRFPCMPFPPCFLVCTRDDIYEDEHGRQWVAAKVETSSHSPYCSKIETCVTVHLWQMTTLFQEPSPDSLKTFNFLPRTWRLESRNTYRGADAMHWRLVNHSQFYGTEELVLMLDSR", "length": 120 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P59528-1", "protein_name": "Taste receptor type 2 member 123", "gene_name": "Tas2r123", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSQKINYSHLFTFSITLYVEIVTGILGHGFIALVNIMDWVKRRRISSVDQILTALALTRFIYVLSMLICILLFMLCPHLPRRSEMLSAMGIFWVVNSHFSIWLTTCLGVFYFLKIANFSNSFFLYLKWRVKKVILIIILASLIFLTLHILSLGIYDQFSIAAYVGNMSYSLTDLTQFSSTFLFSNSSNVFLITNSSHVFLPINSLFMLIPFTVSLVAFLMLIFSLWKHHKKMQVNAKQPRDVSTMAHIKALQTVFSFLLLYAIYLLFLIIGILNLGLMEKIVILIFDHISGAVFPISHSFVLILGNSKLRQASLSVLPCLRCQSKDMDTMGL", "length": 333 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P61314-1", "protein_name": "Large ribosomal subunit protein eL15", "gene_name": "Rpl15", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGAYKYIQELWRKKQSDVMRFLLRVRCWQYRQLSALHRAPRPTRPDKARRLGYKAKQGYVIYRIRVRRGGRKRPVPKGATYGKPVHHGVNQLKFARSLQSVAEERAGRHCGALRVLNSYWVGEDSTYKFFEVILIDPFHKAIRRNPDTQWITKPVHKHREMRGLTSAGRKSRGLGKGHKFHHTIGGSRRAAWRRRNTLQLHRYR", "length": 204 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P62246-1", "protein_name": "Small ribosomal subunit protein uS8", "gene_name": "Rps15a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVRMNVLADALKSINNAEKRGKRQVLIRPCSKVIVRFLTVMMKHGYIGEFEIIDDHRAGKIVVNLTGRLNKCGVISPRFDVQLKDLEKWQNNLLPSRQFGFIVLTTSAGIMDHEEARRKHTGGKILGFFF", "length": 130 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P62425-1", "protein_name": "Large ribosomal subunit protein eL8", "gene_name": "Rpl7a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPKGKKAKGKKVAPAPAVVKKQEAKKVVNPLFEKRPKNFGIGQDIQPKRDLTRFVKWPRYIRLQRQRAILYKRLKVPPAINQFTQALDRQTATQLLKLAHKYRPETKQEKKQRLLARAEKKAAGKGDVPTKRPPVLRAGVNTVTTLVENKKAQLVVIAHDVDPIELVVFLPALCRKMGVPYCIIKGKARLGRLVHRKTCTTVAFTQVNSEDKGALAKLVEAIRTNYNDRYDEIRRHWGGNVLGPKSVARIAKLEKAKAKELATKLG", "length": 266 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P62802-1", "protein_name": "Histone H4", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSGRGKGGKGLGKGGAKRHRKVLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG", "length": 103 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P62963-1", "protein_name": "Profilin-1", "gene_name": "Pfn1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAGWNAYIDSLMADGTCQDAAIVGYKDSPSVWAAVPGKTFVSITPAEVGVLVGKDRSSFFVNGLTLGGQKCSVIRDSLLQDGEFTMDLRTKSTGGAPTFNVTVTMTAKTLVLLMGKEGVHGGLINKKCYEMASHLRRSQY", "length": 140 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P62982-1", "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein", "gene_name": "Rps27a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGAKKRKKKSYTTPKKNKHKRKKVKLAVLKYYKVDENGKISRLRRECPSDECGAGVFMGSHFDRHYCGKCCLTYCFNKPEDK", "length": 156 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P70709-1", "protein_name": "Eosinophil cationic protein", "gene_name": "Rnase3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGLKLLESRLCLLLSLGLVLMLASCQPPTPSQWFEIQHIYNRAYPRCNDAMRHRNRFTGHCKDINTFLHTSFASVVGVCGNRNIPCGNRTYRNCHNSRYRVSITFCNLTTPARIYTQCRYQTTRSRKFYTVGCDPRTPRDSPMYPVVPVHLDRIF", "length": 155 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P81278-1", "protein_name": "Prolactin-releasing peptide", "gene_name": "Prlh", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MALKTWLLCLLLLSLVLPGASSRAHQHSMETRTPDINPAWYTGRGIRPVGRFGRRRATPRDVTGLGQLSCLPLDGRTKFSQRG", "length": 83 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P83883-1", "protein_name": "Large ribosomal subunit protein eL42", "gene_name": "Rpl36a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVNVPKTRRTFCKKCGKHQPHKVTQYKKGKDSLYAQGKRRYDRKQSGYGGQTKPIFRKKAKTTKKIVLRLECVEPNCRSKRMLAIKRCKHFELGGDKKRKGQVIQF", "length": 106 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P83884-1", "protein_name": "Large ribosomal subunit protein eL42", "gene_name": "RPL36A", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MVNVPKTRRTFCKKCGKHQPHKVTQYKKGKDSLYAQGKRRYDRKQSGYGGQTKPIFRKKAKTTKKIVLRLECVEPNCRSKRMLAIKRCKHFELGGDKKRKGQVIQF", "length": 106 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P97876-1", "protein_name": "Basic leucine zipper transcriptional factor ATF-like 3", "gene_name": "Batf3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSQGPPAGGVLQSSVAAPGNQPQSPKDDDRKVRRREKNRVAAQRSRKKQTQKSDKLHEEHESLEQENSVLRREIAKLKEELRHLTEALKEHEKMCPLLLCPMNFVQLRPDPVASWSAHDAPDHPSFIWLGTLV", "length": 133 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q00729-1", "protein_name": "Histone H2B type 1-A", "gene_name": "H2bc1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPEVSAKGTTISKKGFKKAVTKTQKKEGRKRKRCRKESYSIYIYKVLKQVHPDTGISSKAMSIMNSFVTDIFERIAGEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSSK", "length": 127 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q01534-1", "protein_name": "Testis-specific Y-encoded protein 1", "gene_name": "TSPY1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRPEGSLTYRVPERLRQGFCGVGRAAQALVCASAKEGTAFRMEAVQEGAAGVESEQAALGEEAVLLLDDIMAEVEVVAEEEGLVERREEAQRAQQAVPGPGPMTPESAPEELLAVQVELEPVNAQARKAFSRQREKMERRRKPHLDRRGAVIQSVPGFWANVIANHPQMSALITDEDEDMLSYMVSLEVGEEKHPVHLCKIMLFFRSNPYFQNKVITKEYLVNITEYRASHSTPIEWYPDYEVEAYRRRHHNSSLNFFNWFSDHNFAGSNKIAEILCKDLWRNPLQYYKRMKPPEEGTETSGDSQLLS", "length": 308 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q03764-1", "protein_name": "Ethanolamine kinase", "gene_name": "EKI1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MYTNYSLTSSDAMPRTYLVGTASPEMSKKKRQSANCDKPTRRVIHIIDTNEHSEVDLKNELPITCTNEDGEMTSSSWTSQTANDFLKLAYVNAKLDPSLPSQYFKQDIINVLQSLEIPGWSVPGSKESSLNKNLLTLTQIKGALTNVIYKIHYPNLPPLLMRIFGDSIDSVIDREYELKVIARLSFYDLGPKLEGFFENGRFEKYIEGSRTSTQADFIDRDTSIKIAKKLKELHCTVPLTHKEITDQPSCWTTFDQWIKLIDSHKEWVSNNVNISENLRCSSWNFFLKSFKNYKRWLYNDSAFTSKLLREDDKDSMINSGLKMVFCHNDLQHGNLLFKSKGKDDISVGDLTIIDFEYAGPNPVVFDLSNHLNEWMQDYNDVQSFKSHIDKYPKEEDILVFAQSYINHMNENHVKIASQEVRILYNLIIEWRPCTQLFWCLWALLQSGRLPQRPLIEGEKLMSEKAGLGDETHLMEHKNKENGKYDCSEDDSFNYLGFCKEKMSVFWGDLITLGVIDKDCPDIGKTDYLDTKLIF", "length": 534 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q04902-1", "protein_name": "Probable glutathione-independent glyoxalase SNO4", "gene_name": "SNO4", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MTPKRALISLTSYHGPFYKDGAKTGVFVVEILRSFDTFEKHGFEVDFVSETGGFGWDEHYLPKSFIGGEDKMNFETKNSAFNKALARIKTANEVNASDYKIFFASAGHGALFDYPKAKNLQDIASKIYANGGVIAAICHGPLLFDGLIDIKTTRPLIEGKAITGFPLEGEIALGVDDILRSRKLTTVERVANKNRAKYLAPIHPWDDYSITDGKLVTGVNANSSYSTTIRAINALYS", "length": 237 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q0D2J5-1", "protein_name": "Zinc finger protein 763", "gene_name": "ZNF763", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDPVACEDVAVNFTQEEWALLDISQRKLYREVMLETFRNLTSIGKKWKDQNIEYEYQNPRRNFRSLIEGNVNEIKEDSHCGETFTQVPDDRLNFQEKKASPEAKSCDNFVCGEVGIGNSSFNMNIRGDIGHKAYEYQDYAPKPYKCQQPKKAFRYHPSFRTQERNHTGEKPYACKECGKTFISHSGIRRRMVMHSGDGPYKCKFCGKAVHCLRLYLIHERTHTGEKPYECKQCVKSFSYSATHRIHERTHTGEKPYECQQCGKAFHSSSSFQAHKRTHTGGKPYECKQCGKSFSWCHSFQIHERTHTGEKPCECSKCNKAFRSYRSYLRHKRSHTGEKPYQCKECRKAFTYPSSLRRHERTHSAKKPYECKQCGKALSYKFSNTPKNALWRKTL", "length": 394 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q0WX57-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 24", "gene_name": "USP17L30", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEDDSLYLRGEWQFNHFSKLTSSRPDAAFAEIQRTSLPEKSPLSCETRVDLCDDLAPVARQLAPREKLPLSSRRPAAVGAGLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCHRHKGCMLCTMQAHITRALHNPGHVIQPSQALAAGFHRGKQEDAHEFLMFTVDAMKKACLPGHKQVDHHSKDTTLIHQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVQQALEQLVKPEELNGENAYHCGVCLQRAPASKTLTLHTSAKVLILVLKRFSDVTGNKIAKNVQYPECLDMQPYMSQPNTGPLVYVLYAVLVHAGWSCHNGHYFSYVKAQEGQWYKMDDAEVTASSITSVLSQQAYVLFYIQKSEWERHSESVSRGREPRALGAEDTDRRATQGELKRDHPCLQAPELDEHLVERATQESTLDHWKFLQEQNKTKPEFNVRKVEGTLPPDVLVIHQSKYKCGMKNHHPEQQSSLLNLSSSTPTHQESMNTGTLASLRGRARRSKGKNKHSKRALLVCQ", "length": 530 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q1LYG5-1", "protein_name": "Elongation factor 2a.1", "gene_name": "eef2a.1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MENFNVDQIRATMDKKSNIRNMSVIGAFDHGKSTLTDWLVSEAGIVSSARAGETRFMDTRRDEQERCITIKSTAISIFYELAEKDLAFIKECKDGSGFLLNLIDSPGHVDFSSEVTAALRITDGALLVVDCVSGVCLQTETVLRQAIGERIKPVLMINKMDRALLELQLVPEELYQIFQRIVEKVNVTISTYAEDEKGPMGNVMIDPVIGNLAFGSGLHGWAFTLKQFAELYVKKFAGKAQLGPEEYIKKVEDMIKRLWGDSYFDSTTGKFSESATSPDGKKLPRTFVHLVLDPIFKVFDAIMNFKKEETVKLIEKMGIKLDVEDKEKEGKILLKAVMRCWLPAGEALLQMITIHLPSPVTAQIYRCELLYEGPGDDEAAMGIKNCDPKAPLMMYISKMIPTSDKGCFYAFGRVFSGCVSTGLNVRIMGPNFTPGKKDDLYLKPIQRTVLMMGRYVEPIEDVPCGNIVGLLGVDQFLVKTGTITTFTKAYNMRVMKFSVSPVVRVSVEVMDPADLPKLVEGLKHLAKSDPMLQCIIEDTGEHIIAGAGELHLEICLKDLEEDHACIPLKKSDPFASYRETVSDGSKQLCLAKTPNKHSRLFMKACPLADGLAEDIDKGRVTASQEMNARAQYLAENYKWEVTEARKIWCFGPEGTGPNILVDLTKRVQYLNEIKDSVIAGFQWATREGVLCAENMRGIRFDIHDATLTSTAIHRGPGQIIVATRRVLYGCQLTAEPRLSEPIYLVEMQCPESVIGNVYGELVRRRGVVFSESQVMGTPVYLLKAYLPVSESFGFTADLCANTSGQAFSQCVFDHWQILPGDPMDPTSKVAHIMADIRKSKGLDEAIPALHCYLD", "length": 854 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q1PEY5-1", "protein_name": "Probable 3-hydroxyisobutyryl-CoA hydrolase 2", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MASHSQVLVEEKSSVRILTFNRPKQLNALSFHMVSRLLQLFLAYEEDPSVKLVVLKGQGRAFSAGGDIPPIVRDILQGKLIRGAHYFKVGYTLNYVLSTYRKPQVSILNGIVMGGGAGLSTNGRFRIATENTVFAMPETALGLFPDVGASYFLSRLPGFFGEYVGLTGARLDGAEMLACGLATHFVPSISLTALEAELYKVGSSNQTFISTILDAYAEYPHLNQHSSYHRLDVIDRCFSKRTVEEIFSALEREVTQKPNDWLLATIQALEKASPSCLKISLRSIREGRLQGVGQCLIREYRMVCHVMKGDISKDFVEGCRAVLIDKDRNPKWQPRRLEDVTDSMVDQYFERVEDEEGWEDLKFPPRNNLPALAIAAKL", "length": 378 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q1ZXA5-1", "protein_name": "ADP-ribosylation factor-like protein DDB_G0292332", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MDFIISFIKNLFGFLTIKKVMILGVENVGKTTLLYNIYKFYSENITTTTLSSLPIPIPTNGFNVESIVIEQVKFDIWDIGGKETNRICYRHYLTSEIDSIIFVFDSSDINSLEESKKEYQYLKNQISLKNVPFLLVANKQDLKQQTIEIDEILKTYFDKSSINETILMSQNNNDDLIKCINWIFSN", "length": 186 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q1ZXJ4-1", "protein_name": "Acetyl-coenzyme A transporter 1", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MLFTLLKRHFGNELNNIVWLVLLYLIQGIPIGLSFGTIPFLLHKHATYTQIGIFTISTYPYSLKLLWSPIVDSYFVQSFGRRKSWIVPIQILAGIVFITISFFIETLLEHAETKIIYITIVFFLLIFLMATQDIAVDAWALTILSKPYLHYASTCQTIGLNTGYFLSYTIFLTLSSPKFANKFLRSVPSEEGIITLPGYLQFWGILFIILSIYLAFFKDEESTTITTTTTRHDNYNNNNNDDKNKQVKSKIENESIESKSMRSSPSSLSPSLLSSPVKKQNKKNKQHISIDKKDITIIKENNENNEIIDNNNSNNNYDNGKKSIVQETYGMDISESDLTPKQVYYLLWKIITLPHIKILSILFIISKIVFQPNESALNLKLLEKGLRKEDIASFSLIQFPSIIIFSIISSKWVKNKPLTIWSNAYLVGVFFILVNMCSVFYFPNLNGGEISWSHFFLLLMISLFSSFSYNLMSVSQGSFFLKISDKSIGGTYVTLLNTIANFAGTYPKLFILMLIDKLTTSECIVNISNDNSSSSSSSSSLISTSSNNLTTTTTIIQEQQQQVIIHDNISKELCAEQNGKYRIERDGYYLVATGAIIYGVFIYFVLKRYLTPIEKLKL", "length": 618 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q23888-1", "protein_name": "Large ribosomal subunit protein uL2m", "gene_name": "mrpl2", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MVLNWRGVKSRLYSGKRRIDGRNKGLIAIRSRGGALKRKYRYIEHYKQKWMDKWLFVMRIEYDPNRSAHIALCSILKEGIYFYVISIAKLEVGSLIITSALKLGTLQVGNTTKIKNIPEGLLINNIELIENSGSKISRAAGTSSLIIKKYNKKYSLVKLSSKECRLISNECYATIGTVSNIERKLKQNKKASYSRKRGIRPIVRGLAMNPVDHPHGGRTKGGVHWKSFSGKLAYNVSSRKKTKMTSRYIIIGHRKQKIMDKQIKNG", "length": 266 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q24113-1", "protein_name": "Protein no-on-transient A", "gene_name": "nonA-l", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MEGAVKKNSLNSSPLPQRQQRGNSTNKNLGKPTPPKLNAASDGNPAEKKARLGGNTQNGGGVAGGGGTGGGGGGGGATGGVEFSRNRNRGGNQNENRQGFQVANNSHQKQINESPKPAAGNVPAKNNELSAGGGGQNQPNHSNKGQGNQGDQGEQGNQGPNFRGRGGGPNQPNQNANQEQSNGYPGNQGDNKGGQGQRGAGGGKHQRGNRSRRSGGSGIMNSSMGGGGQRGEDFFIAQRLLDISGPTHELPPIELPTDNKFVGRNRLYVGNLTSDTTDDDLREMFKPYGEIGDIFSNPEKNFTFLRLDYYQNAEKAKRALDGSLRKGRVLRVRFAPNAIVRVTNLNQFVSNELLHQSFEIFGPIERAVICVDDRGKHTGEGIVEFAKKSSASACLRLCNEKCFFLTASLRPCLVEPMEVNNDNDGLPDKTLNKKSLEFRHERSVGPRFACLNSFEHEYGSRWKQLHDLFKSKQDSLKRELKMEEDKLEAQMEYARYEQETELLRQELKKRELDNERMKLEWEMREKQAEEIRKREEEYMHRYQNQLLRHEEDMRARQQENDLLMQAKKLNMILDQQEGFGGSNSGFEHFDSPFEVFGNNSNNSTMAGPGGPDNSDGNQHGHIDSWGHRRF", "length": 630 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q2PRK7-1", "protein_name": "Odorant receptor 106-10", "gene_name": "or80a10", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MANETFVKNVDSFIITGFDHLQNQKLLGSLILISYMFILLGNGINLCIISTDRHLHKPMYILICNLAVVDIMYSSTCSTTMISVLLAEIKTVSYYSCISRTYFFNLGDLTECMALTLMAIDRLIAINLPLRYHSFVTNSRILWLIFLTWIFSFAVIGFLTYVADTLPYCQPIIKYVFCSYSSLVRAACVDPEPYFAISTVYSMVTLCGLFPFILCTYAVLAYSVTKLANSSRKQMINTCLSHIIVLFSFYLPKIVYILLTRIGLVLTLTERNAVLIVSCFVSLLVNPTVYCIRTKGIRKRITDIFLYTQKITK", "length": 313 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q2YDJ5-1", "protein_name": "Uncharacterized protein CXorf66 homolog", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MNLFIYVLLLSIWTSSCLDRNESNGSATAVTTHAEFKQTKLQELRRRLLIIVIGTLITGYMVSCTCLLHYSCDSEEAHTAAKDKKEDITIKASRSSKISFTDSKSPTAGLGDPERQSVVSRIDKSSGPSSPRKVPSSAEKLVRPSSQKKPSKPSAPKKVLGSPPQEKLHRTRSPKKAHRQAHAHKPVSQVSPSYPEKAIKSTWPPSLQCRAKPTKTPLPYPKNQSFPEQSSVDKLTKRQRYLKLKCPASAGRAEILSRPHPVKFCRCYKEKCLVCRAVSEPFITHVSDANKKHVPVPLFSRELKHFYKSYKKKQPKYNTLYGNMSDSDITTYNSDGESDREVIIMCNIKCKEDIYKNSRNN", "length": 361 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q3L180-1", "protein_name": "Alpha-defensin 26", "gene_name": "Defa26", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKTLVLLSALFLLAFQVQADPIQNTDEETNTEVQPQEEDQAVSVSFGNPEGSDLQEESLRDLGCYCRKRGCTRRERINGTCRKGHLMYTLCCL", "length": 93 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q3TR54-1", "protein_name": "Gasdermin-C4", "gene_name": "Gsdmc4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGYSFDRASKDVVKKLQGRDLRPVECLSDATKFRLFHILQETPRSGWETEDIPVGFTLLDLLEPNFPVPEPEVSAPKPFIHVQSTDLEANLNVADIARGGVGYVGYGGYNIEVQSTSIPNPKLEILQNRKLLDKLPTFMKFCRMERKNLYVVTEAYEVSKDTMLTGLSSVNLLVKGFFKQLFKVRGKAGRSEKYSIPIPKGSVLAYKKQQLVIENNTCVILPSATKKKMTFPDRPLKLYDLPVTLRYQEEVIETGSWIDDIDPIGTIEEPANLNFMCLQHEVSEQTQLLAELSKDVQEVVFSSFLHMLSDRDVLYDLMKMLELNQLGHMDGPGGKILDELRKDSSTPHDVLKDLNLYLLQALLVLSDTQLCLLAQSVKMGLLPHQVELVKSILQTNFKYSSNTPFTLQPQLLAPLQGEGLAITYELLEECGLKMELNNPRSTWDLEAKMPLSALYGSLSFLQQLQKANSSSKPSLSPGYI", "length": 480 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q3U0I6-1", "protein_name": "Endoregulin", "gene_name": "Erln", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGQMVPPRSIQNEDFWKNPWDVGGLTVIGLFTSTFLLFVLFAVVFGYVEKAVFEEE", "length": 56 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q3URS2-1", "protein_name": "Zinc finger and SCAN domain containing protein 4F", "gene_name": "Zscan4f", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASQQAPAKDLQTNNLEFTPTDSSGVQWAEDISNSPSAQLNFSPSNNGCWATQELQSLWKMFNSWLQPEKQTKEQMISQLVLEQFLLTGHCKDKYALTEKWKASGSDMRRFMESLTDECLKPPVMVHVSMQGQEALFSENMPLKEVIKLLKQQQSATRPTPDNEQMPVDTTQDRLLATGQENSENECNNSCNATEANVGESCSGNEMDSLLIMQKEQHPEHEEGNVVCQFPHGARRASQGTPSHHVDFPSAPTTADVPMEEQPKDLSRENISEDKNNCYNTSRNAATQVYSGDNIPRNKSDSLFINKRIYHPEPEVGDIPYGVPQDSTRASQGTSTCLQESLGECFSEKDPREVPGLQSRQEQLISDPVLLGKNHEANLPCESHQKRFCRDAKLYKCEECSRMFKHARSLSSHQRTHLNKKSELLCVTCQKMFKRVSDRRTHEIIHMPEKPFKCSTCEKSFSHKTNLKSHEMIHTGEMPYVCSLCSRRFRQSSTYHRHLRNYHRSD", "length": 506 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q3ZCQ0-1", "protein_name": "Required for drug-induced death protein 1", "gene_name": "", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTVGARLRSKASSLVGRGPLGRLRRAGDEETDAIVEHLEGEDEDPESQDCEREEDGRRAGTPSARRVHLAALPERYDSLEEPAPGDKPKKRYRRKLKKYGKNVGKAISKGCRYIVIGLQGFAAAYSAPFGVATSVVSFVR", "length": 140 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q4JEI3-1", "protein_name": "Defensin alpha 3", "gene_name": "Defa3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGTLTLLTTLLLLALHTQAESPQGCTEDQKLLIMEDQDISISFTGDKGTALQDADVKSGVICNCRPRGCSFKERVYGECGYNGHILRLCCQPLNTMNKKSPSVI", "length": 104 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q4JEI6-1", "protein_name": "Defensin alpha 8", "gene_name": "Defa8", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKTLVLLSALVLLAFQVQADHIQEAEEETKTEEQPADEDQDMSVSFEGPEASALQNLEIGWPLKQCHCRKFCRPYEKAEGSCRPGLFIKRKICCIQQWTPGRT", "length": 103 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q4KL71-1", "protein_name": "Small proline-rich protein 2A3", "gene_name": "Sprr2a3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSYYQQQCNQPCRPPPVCPPPKCPEPCPPQVWPGPCRPVMCFEPCLPSVWPGPCRPVVCYEQCPPQPWQSTCPPVQFPPCQQK", "length": 83 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q504N7-1", "protein_name": "Pyrin and HIN domain-containing protein 1-like", "gene_name": "Ifi214", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVNEYKRIVLLTGLMGINDHDFRMVKSLLSKELKLNKMQDEYDRVKIADLMEDKFPKDAGVVQLIKLYKQIPGLGDIANKLKNEKAKAKRKGKGKRKTAAKRQRQEEPSTSQPMSTTNEDAEPESGRSTPDTQVAQLSLPTASRRNQAIQISPTIASSSGQTSSRSSETLQSIIQSPETPTRSSSRILDPPVSLGTAYSSAQALGVLLATPAKRQRLKNVPKEPSEENGYQQGSKKVMVLKVTEPFAYDMKGEKMFHATVATETEFFRVKVFDIVLKEKFIPNKVLTISNYVGCNGFINIYSASSVSEVNDGEPMNIPLSLRKSANRTPKINYLCSKRRGIFVNGVFTVCKKEERGYYICYEIGDDTGMMEVEVYGRLTNIACNPGDKLRLML", "length": 393 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q54B59-1", "protein_name": "O-methyltransferase 12", "gene_name": "omt12", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSDWDKTMDLLFGFVTGHIHSRMFETILKFSICDLLEDGPKHYSEISKIIGFKNESYCYRLMRYFVPYKLFNESVVQVGLFSKTPSSTQFSKNGTLKNLGRFHCQDHHYRIFESLPKTLEMGKNQGPSSIGLSSFWEHFETDESYKQLFHNAMKDYTSLIIDRLISKISLSPNFKTVVDIGGSHGFLIGKLLESNPNIHGINFDLENIINSSTSKNENFQHPRLKHVSGDFFNSVPEADCYILKYILHDWSDEKCITILNNIHKSLKPNGKLFINDLVLDPSNYTKEAVFKDILMMQYFDAKERSINEWHQLFEKCGFKIDSVDTSISPQLMIVSKINSSNINLNDCTNFNSEIVEEKLKNSLPQFVNC", "length": 369 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54B60-1", "protein_name": "Probable inactive O-methyltransferase 11", "gene_name": "omt11", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MECSESLELVDKFACGHILSRMFNVVMKHSICDLLEDGPKHYSEISKIIGFKDDSYCYRLMRYFVPRKLFKESVVQVGVFSKTPFSTEFSNNGTLKKLAKFHCNSFHYKLSQVLPETLEIGENQGPSSIGLSDYWEQIEKNEIYKNEFNDGMIGYTTHILKFLKGKIDLSKFETVVDIGGSHGYLIGSLLDRYPNVNGINFDTDMVINSSNEKYQHPRLKHVAGDFFKSVPEADCYLMKLILRCFSDEKCCELLKIISKSMKSNAKIIILDIILDSSKYLNFDTYLDILMMETLDGKQRSLSEWIKLFEMSGFKIDKYESGSPNYLIISKE", "length": 331 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54B86-1", "protein_name": "Hly-III related family protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MPRLDHKKNKEEKDNEPLMMVNNYNIGIQTDNNQEDIQNDYHHFNDLSINIKNNKNNNNNNNKCNSLHHKHYHNRFIINGGNNNNDNNNNNNGDDCCANIELFVDLMLSENEYILSGFRLHTKNSYMECTKSIFKLHNDTLNIWSHLLGALFYLVLFFTSIIKIIKLNNNDGGGGGGIGNNFILNSDEIKLLETIDLPSNFNYLFFQLSCFICFLSSTIYHTYRSHSIVVFKTTLMLDVASIALLILSSVCLIIDSELSCWPYFKRIYLFSFLILILISFLSLPKIMREKRYGLRTFLFAILALQGLVGHLFKIYLQGYFDKDPNQFYNLIGAYTLFGLALSIRRFKVPESFKPGHFDVWVNITFNIVYNII", "length": 372 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54BG8-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIKIMTWNCQGCSTIKSMNQTKNTINLIKPDISILTETNLKKDQNLAQIKNHYSTGGKGKEARGKGVMAINHLEQIEIKNLEEKEGRILKFTAILNNMEINIICIYAPASYDRRKGWFSNNISLEDLEQADIVTGDFNINKYAKIKFKDGSSDKRKFTENETIEFLMMEVGLTEILPNSTTKTTFKDKLIDRTFLSTKMHQLNHSYKIIDKINKSDHNIVVMDFKIPNFTKIYKSPLWKMNSIIIKEDKTIKKIEKIIDHYQETKRKNINITEYWIKFKKKIKKQCITTEKKRILERKKTLSNLANEHTKTKNKYEKETISNEITILQEEERIDRMIKSSINYINNKEIASNLLTSILKKRDSSSQIHRIKNPSNGKIETEQKEITDCFRKYYETLFKEKECDQETHTELLSTWNPPIDKKKLTEMEDRIEEYEVKLAIEKIAEGKSPGEDGITSSFYKIHQHKLIPILTELFNFFLNNEIPTEFKNGILTSIYKGKGDVLEISNRRPITLLNVDYKIYSKIINNRILKILPNIISKYQNGFIPGRLLHNNIIALDLAMEKSDRNTIITFYDFEKAFDSISHKALIRTLNHLKFPRKITNTILSMLTNTNIRVMVNGQLSESFRAGRGTKQGDPISPTLFAIVCECLSTSIRKDNTIIGIKLNQNNSMKIGQYADDTVTLASNIDDADKMDMKVIKFCQATAAKINDNKCVCITKNPKIKTKYKTIGAKEEERYLGFFFNRKGVISKVDDTVNKLENLTKCYSSVSSTLKGRITILKSYLLSQLTFQLYINEINDIKKLENVNANMLFKGDRWAISKERSRRDYEIGGLELWNMATRSNAQKAWIYEQYLREKDDQNCPPHMEVWKSEKENSLSRIHIKCWKAWKLLHHPRERITLKLNQVKPKYENKQKLKVIYRNMMDIKYKGWNKHQPTTGQKLIQKNINHPILPFREARSITTIKGRDLAWRYLLKALPKHHGENCHSCKEEESSMHIFFECKSIKQNIDSIYQKVCKDSNNTYHGPWSEKVLGKLLTPFSSNLIGAIMESIWYRRNQIKFNDNTTIITENQIIHKIKKARDAEWDRTRKIVEKQLRQELRCTDNRESINRTASIKRRLEKFSHNWNSKLMTINIPEHFIPYCSYNTNYS", "length": 1144 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54C66-1", "protein_name": "RING-type domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MYKTKKYKNPFPTNSYKEPENDSDNEYILHNEEDNEDYGSNNNNINNDGFSYEDNIENSDTEDEREDYGYINYNTNNEEDDEPIDLSTPIKKKKANNKSFKPPYKNTTTTTTTTTTTPPTPPPSKSNNNNNNNNNNNNNNNNNKNKENINKESEYELNKFLDLYNDFKSESDNKVKPTATTTTTTTTTTSTSTSKLNKDKKGVIVIESDEEKEDNTIKINKRNGKRKEGEQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQGNEDNLKSENFNKFKKLKSFSNQPTPLPPMLSNPFLNNSGNSHNNNNNRILFNSQFTNASNLNNNINNNINNNINNNINNNINNNINNRNNNTNNYTNNNNNNNNNNNNTNNNNSNNNINNNNYNNNNNNSFSFLPIRSNTLPTIVTRRTGIQSSSSDNGNSNSNHSSSMNKRNTSKSNNKKSTTTTKTVLPPPLSSRTQEEEDYALALSISEGLNGGSGGGSGSGSGSSDNSTKTKRSKSENDLPNEETRHQVEMDRRFAEQLHREQHENINQIQQLQRRLHLNQQRTNNINRNHHGDEDEEDIEMLNLRAYQQIQQQFNQHFNQQLNQLANHPLANLFSHASRGRGRGARRIPHHPHHHHHPHQAQYLTGLSQEQLNLMTRDFSSNDYELLLQLDENINNKGATTSDIENLPVHTLNKPTATTTSTTTTTNSSTSDDNKKNEPTTDVTCCICLCEMEPGDAVRTLPCKHFFHVSCIDQWLKVNKVCPIDKKAIDEK", "length": 766 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54CY8-1", "protein_name": "Obg-like ATPase homolog", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIKGIKLFNNFTNTKQILFFRSFSTAAKGDRLKASHYVKTRGSCKSISIVGLPNIGKSTFFNALTSSNAAMAANFPFCTIDPNIGKVFVPDERLDYISDLLKTKSKIGVQLEFVDVAGLIKGAADGEGLGNKFLGNIRQTSLICHLVRCFEDKGITHVSDEIDPIRDIETIETELILADLQSLEKMLTEGKKKQSNPELQMKFDLVKRISEYLHKGLPARDVEITDMEWPVFHSLHLLTSKPTIYTCNVAEGDAATGNKYTDLVKEYSKSKGLEIEPVVISAKIESELANMEGNDETKKEFLQLYGLENNGLSKVINGAYKLLGLQSYYTASSNECHAWTFKAGWTAPKAAGVIHSDFEKGFIKCDTISYNDFIECKGDEKIAKEKGKQRSEGKAYIVNDGDILFFKFN", "length": 409 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54D44-1", "protein_name": "Probable polyketide synthase 42", "gene_name": "pks42", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIESQREFNCIGGDNQNGVAVIGVGFKIPLDLENCLSSPSELYSALFNEFDSVTKNTSSRWSDNYFKNGDIVSLSAGLLPLREIKSFDPTFFGINPSDADLIDPQQRLLLKCVWNALEDGGIDPISIRSSDTSVYIGCSTIDYFLLNRNPVDPHNHGIQTASYSIPNRISYCFDFRGESLFVDTACSSSLNAVHLGYNSIINLKSKLSIVGGSNLILDPQNSIFFSKQQVNGPSGKCNSFSEEADGFVRSETVGVVVLKNLKDAIKDGDRIYCVIQGSNSNVDGNYEKLNYISPSKLSQAENITKALKSTNGAVNASDIDYFECHGTGTPTGDPIELEGISIALNRTQQSTTLSNPLLIGSIKSNIGHGEASSGIASLIKCCVMFKYRQFLPNINFKTPNPLIKFKEWNLKVVTEPVPFNNNKQTIMAINNFGVSGSNCCIILSEYKSNNNNNNDFKATTHLKSKKFIIPFSSNSSTSLDNYKSLLSNETNNFQDFVIKQINNKSTSLIQRSVIIASNWSEFNESSNEIQSNIKKSIISNITIKKKNAVTVFVFCGQGSQYNKMALSLYENEHIFKSTMDKLDKELSKHYGYSILEKLRSITDEDLVTIHQPILAIPVNVMVQVSLYELYKHWGIKSDIMVGHSFGEIACSYCSGMVDFKTLCYLTYHRSVAQNKTIGSGKMLSINIGAKEYLDSYSTKYPSVEIACYNSETSIVIAGNEELLNEISKDLKSKDIFTAMLPSLSAFHTTHQSVIKDDICSLNFKSTLSKITVFSTVTSNQFGINNNNNNNNNQLNSNYLFQNVIQPVKFSETISNIYKYIESNDMGNEITFIEIAPHPTLQYYLNQMKSQQSEYFNNGEKISIYSACNKKKNDYNEFLKTISTLFVNGYNNINFKSQIINNNNNDNNNNFNLPLYQWDDNEYYKIHPTWKKANKNGPSINHLGNLNDSSIKSFKTYINTRKPQFQWLKGHSLKGKVVFPGMGYISNLLSVYNMNQDITINEIQFKSAFILVDGVNNCLETSIVPLTKNEFNIKFHFKDLKTNKWVLCANANYSLFKHNDNNDKLDIEKLKSNCNYTIISKDELYNNIRAKSGLIYKGLFQGVKEAFIGNRCSLTVLSLNEIENQQEFKHLLENRNFNSLFNTAILDSCLHGSLHSKEQSQIYFDKCEGFKYYSNNINLATSKRNEYKEINVYIETNPVINSTVIVSLKIMLPDGTLLIEIQKVVCKSSIPIIDSTSVIQPSPKDLHTPYYQPKNSLIKPPQSFKHLHCMKEFASIESDNREMVYMSIYHLIFKAINARSPTKINLESLENLTLDQFKELIKDSAANIQRSNQFIYECLKLYHTNHSNYKKNQIKDFIKECEDFNGYNQIIFKTIKIYAKSLFPLPDDDPFTDTIQSLFEDDQLENVYIHLKHLYPVNNLLSEIVFQSIKPIINQTSTFRILEIGAGYGTISQLIFDKLEQLLADNFTSSRIDIEYTFTDISNTFLPRAKERYSKYKRFNIIYKLLDLELPLTEGIQDFRPLYYDIVVMSNVLHVVKDINFSTNEIYKVLKQNGQLIFVEPTYKNLYLDTIFGIFPQWWSFNDDIRTDRCCLEPSKWFEFLETINFKDTIILGQDNKEILKNVENSIILVQTRKPSQLELSINNSPSTNQFKSFENIILYTDDNQQPNDCSEIIDLLKSLELPIKIINNIDQFNQIIKTQYNNNNNNNNNNNNNNNNNNNNTNNNLIIFLKSVNQLNTNNYKDITFEYVQINQILVKLELEENYKLLLITNNSQSSNYLSNSLIGTSRYLFADIVSSKLDIITIDFDTVSIKNHQNVISVINHLLDSKDNSEREYYIINNEINIERYKNESNIKHQLKSKTFQENKDELMVQLDSNLEYRLKSKSKQELKSTHVEIQVKAIGINYKDYATYSGLIDSIIEIDKDKEKDENYDQNYPSIGNDFSGVITRIGSDVRKFKVGDEVCGLAPKTSASHIITEEGYLCKKPSNISHSEAASSVTVYTTSFQSIYSIGDLKKNETILIHSGSGGIGLSALEILKWKNHQGYIFATVGSEDKVKYLTDTYGSFITGIYSSRDKDYQDQIKEKLKSLGCDIDHQGVDLILNTLSVEYMDSNFKCLNQKGRCIDLSITHLTPFDYMDYNKFKFNVSYGNIELVVLPSKIIKDHLKKMLKAFSLGSLRFIPIVEFSNLNIRNAVEYINQRKHIGKIVVKNDVDFINKLFIEQQQQQNSVENNEILMKDKYDISNLELGKNILLTGQTGIILTILKWLYKHSNNSIENIIIISKSKLKWELELFINESTNNRIKIHYKQADVGNNNELNQCFEELRLRHSIEDINSIFHFAFINDIGQFEDVNMNRMDIAHHAKAIGSLNLHNQSIERKWNIKQFVLASSALSVFGGDNQCCYISACSVLDSLSKYRKSIGLPSLSINFGGVTSTGFVSRSGAVEANLESSIINLITPQSLISSLDLFIQNSQTFSNYTHFNFIYDNIESYSLNRMLFKFDYLINQHSSLVSNKRLGGINENNNIGDLLVSKIGELLSIEPSKLNLDFRLVDYGLDSLVIVQLKNFIDKQFQPHLISILQLQNNKISTTIEIIIKGYNNNQNKKIKNEQSNDIPSVVQKETIKDNNENKDDIKIDMDDKKENLKGKKENIDDKKENNN", "length": 2655 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54E06-1", "protein_name": "Transmembrane protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MTIINNDNISLATSAKLSQFIVSGDYKGPFTIIGLKTKILSFSLVIEFILLKIELIKERKDGLKINFDDSISGSCNYELNYTKQDTLFQRFQSKFKIEHTINPENGETINTGITLKKLFIISIPMSILFVALNWIWMLAISMTEVSISTALYLKILKTISVIIFMGGIVGIAITTVGTSKGEYPHAIKGEILMIISAAMWGLYEVLTSKFIGDANRTIVHTYMGLIAFVNLILGIPVIVILNVTNFEPFSVPSISVFGMLLLNAFVGFSVNYLINWGLSVTSPLFVRSGELMVIVATLLFDIIIKHMKLPLLALPGYSLIVIGFILSVYIESRDIKQQQEKEKEKQKNNNGETESLLNY", "length": 359 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54EC9-1", "protein_name": "DUF781 family protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MLNKIILIFFLINNIFSIVVSSTKLNPWVFEERIKLYDILINSTKVEIFGDDNLNNCFQGFKIQLEWQKTTGRSMIIDNSNISVNSWWGSMNYYESIIPFISAMNLGIIQPPIELVNIGDDRFCTDYSECDKELMEPWDLYFQFLIKIKDEKYSYSIQQQILKYNWDGHMKSLSIGLKLFNDKLNYLSKNEIKFSTGFVHFVDIISLINFNTNYSQILPIFDSLPPRMLTNSDHPPFFKGFTRTQNFYTVSVLSINELHENQILWNYFLNLLKTKTENEKCRDFINQEIINFTKYPESTLVKLLLKLLLNNC", "length": 312 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54ED6-1", "protein_name": "Probable polyketide synthase 41", "gene_name": "pks41", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MDSKNLVDENCNKVAIIGIGFRFPNLKGDITPNELWSKLLNRYDGIVKNDRWNESFFKSGDISTNYAGFIPFEELKSFDPLFFGINPSEGIHMCPQQRLLLKCTWEALEDSGIDPIEIRGSNTSVFIGCSGADYQNLNKNDNKVQQEIFSSSTHSISNRVSYCFDLHGESMTIDTACSSSSNAIRRGYKSIIDGSSNISVVGGINILLDPNISKSYSRLNILSKDGKCKSFDAGADGYVRSDAAGIAILKNLNDAIKDDNNIYCVIDGSASNVDGNGFSDKSNFYSPSKSSQVECIRLALESTNGQVNENDIVYFEAHGTGTPTGDPIELESVSIALKTSENRSSDNPLLIGSFKPNIGHTESASGISSLIKCCLILKNQCFVPNLNFNKPNPLIKFDQWNLKVVTDPIDFSTLNYINKRVSIAINNFGVTGSNCCLIVSSFKGNQIRNNINNKSKSPKQYLIPFSTNSIKSLDLYKSRIDNNVEFKEFAENQIKSKSKKLIQRSVVIASNWDEFNLKSNTINTSNDKLTSNMLVSSNKKNVTMVFVFCGQGAQYSTMAKNLYDNEPIFKKSMDKIDSKLNEYYGFSILEKLRSFNENDLKGIQYSIIAQPSTCMVQISLFELYCHWGIKPSIIVGHSLGEISSSYCSGMIDLDTFCYLIYHRSMVQSKTNGLGRMLSISIGENEYNSKYSSRYPELEIACYNSPSSIVIAGKELILNEIIKELKKDGVFCAILGSPTSFHTSSQLSVKDEILKISFKSKQPTIPIFSTVTTNLYDEMNPFDTKYVYDNIINPVRFTNTISNIYKHIELNYSVNNNSNEVIFIEIAPHPTLSFYLKQMVPEDKKQSVSIFSPLSKKKSNDLFEIQKLISELYCLGYNGIGFNIQLSDHNNTNNQTRVNLPLYQWEDQEYWKLDNLHQYHLSNGPSINHLGISNSNHTPIKSYQTHINIQKKPFQWLKGHQIKGKYYFPGCGYIDNILKIFGESKTDTNPNKELPDILISFIEFKTPLIFMDGISQCLQTNIHSTGKKEYKALFHFKDEKSSSDWVQTSTANFQLFSRGPNLNEDDEQSLFMYNINDLISNQCNLTKLSKQELYSHIKTKCGLNYSGDFQRVDKCYLGYNCSLSEISIIQGVNENRSTFFDSSIIDCCLHGSIGLIDENCQLVFEKLEELTYYSSKVPKTTSQHSKIYVYSKLKPRIGDSYSASIIVMLENGTVLFEMENASFKSTTKIKDPLAMEYPTNEIYSCNLQSKDSLIPSLSSFDHIFKRKIPNEYVDQINIYESFIPKLLFSNINKRCPEITIDEIQSSEIEQLLLKYYKIKEDNDNKWLSRLFTFAFESIKQWYHNEDYDFENVLSPHNFKIFSKSTKIISKLLFPLENDNDEDSPQSLFEGGLLDKFYSSGFSAQNELVGEIIQESIKPILNEKLVFRILEFGGGVGSLSLLVLEKINSLLIQYPNYQIDIEYTWSDISPSFITEAKAKFEKFNDRFNIIYKALNLEQPLIGEKQGLKPQYFDYIIMFNVLHVIKDVKYGVEQIYQLLVPNGHLLFIEPIYKSIIGDGIFGVFDQWWSFQDTEIRKDRCCMKQKTWYKLLKSVNFNDDIRMTPELTCFVIQAQKPSISNLSFSKSETTNYDSIIVFGNKYASNLSNHFIKSIDNGNLQFISTIEELNKIGKYISNESIIYFIKSIDELSVDNFVNITHEYTQINQKLMELNCKCKHVLITNDSTTTNYLSSSLIGAARYYHECPLELFILNFDTPSIIENQNLFKTIEPLINSSINIQREFIINNHKVYYERIKNETKLKSIFKNSSSFESLEQVDNFMISLTPNLEYKVKVKPTSILKENEVEIKVMSTGLNYKDYLIYAGLVESVEPIFGIEFSGIITRISTGSKEFKVGDHVYGIGKSTTSSHIITDIDVISHKPSNISHSEASSIPVVYLTSYHSLYNIGALKNNETILIHSATGGVGLSTLEILKWKGHSGLIFVTVGSNEKEEYLRENYGDMISGIYSTRNKNFVKQIKSKISKLNPFGKSGVDFILNTLSSSDYMDSNFKCLNMSGRIVDLSITHLNSNEFTDNKKFKYNYGYHNIELQYVDKKIIKSTLSIISNAVSSNDLQLIPITHYSIEKVKESIEFINERVHMGKIIINHENQDSIINELIEKQKSINKFDQSIFKQNYKLEPSLLGRNILLTGQSGIVLEILKWILRNSENNSIGNIIILSKSSIKWEMEYLINKVKLINKLGNFFNNIKFHFKSVDISDSGLIDESINKLLIENPDINNIDSIFHFAYTQATCNSDEVDLHHLTQSHSAKSMGAINLHNQSIKRNWKLKNFIMSSSVSSKTSTANQCGYISSNNVLDALSKYRISIGLPTICTNYGLIESTGFVSRNESVAALLSGEGFIPISANLILGTLDLQLQNQAQSSNLILSNFNFTSLNGLPQKSLISKFDYQININEENEKSKSLLKDDNVELTVDQLITFKISEILSTDILKLNKDIILVDYGIDSLVIIQLKNWVDKEFSIPNELTIQKIQNSTINSFIQLVKNSMDKNKK", "length": 2542 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54ED7-1", "protein_name": "Probable polyketide synthase 40", "gene_name": "pks40", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MDYKNKYQSNENCNKVAIIGIGFRFPNLKGDLTPNGLWSQLLNKYDGIVKNDRWNESFYKTGDIPTKYAGLIPFEELKSFDPLFFGINPSEVIHMCPQQRILLKCTWEALEDSGIDPIEIRDSNTSVFLGCSNFDYQNLNKNNNKIQQNIFASSSHSVSNRISYCFDLHGESMTIDTACSSSSNAIRRGYKSIIDGSSNISVVGGINILLDPNTSKSYSQLNMLGKDGKCKTFDADADGYVRSESAGIAILKNLNDAIKDGNNIYCVIDGSASNVDGNGFSDKSNFYSPSKSSQVECIRLALESTNGGVNENDIVYFEAHGTGTPTGDPIELESVSIALKTSENRSSNNPLLIGSFKPNIGHSECASGISSLIKCCLILKNQCFVPNINYNKPNPNIKFNQWNLKVVTDPIDFSTLKLSNKPISIAINNFGVTGSNCCLIVSSFKGNQTNNNNNKSKSPKQYLIPFSTNSIKSLDLYKSRIDNNVEFKEFAENQIKSKSKKLIQRSVAIASNWDEFNLKSNTINTSNDKLTSNMLVSSNKKNATMVFVFCGQGAQYSTMAKNLYDNEPIFKKSMDKIDSKLSEYYGFSILEKLRSFNENDLKGIQYSIIAQPSTCMVQISLFELYCHWGIKPSIIVGHSLGEISSSYCSGMIDLDTFCYLIYHRSMVQSKTNGLGRMLSISIGENEYNSKYSSRYPELEIACYNSPSSIVIAGKELILNEIIKELKQDGVFCTILGSPTSFHTSSQIPVKDEILKISFKSKQSTYPIFSTVTTNLYDEMNPFDTKYVYDNIINPVRFTNTISNIYKHIELNYSVNNNSNEIIFIEIAPHPTLSFYLKQMVPEDKKQSVSIFSPLSKKKSNDLFEIQKLISELYCLGYNGIGFNIQLSNLNENDNIQTSLSLPLYQWEEQEYWKLDSLYQHHLSNGPSINHLGISNSNHTPYIKSYQTHIDIQKKPFQWLKGHQIKGKYYFPGCGYIDNILKIFGDNSESTTNPNKELPDILISFIEFKTPLIFMDGVNQCLQTNIHSTGKKEYKALFHFKDEKSSSDWVQTSTANFQLFSRGQGLNEDDEESLFKYNINDLISNQCNLTKLSKQELYSHIKTKCGLNYSGDFQRVEKCYFGNNCSLSELSLSQGVNENRSTFFDSSIIDCCLHGSIGLIDENCQLVFEKLEGLTYYSSKVPTTTSQHSKIYVYSKLKPRIGDSYSASIIVMLENGTVLFEMENASFKSTTKIKDSLAMEYPTNEIYSCYLQSKDSLIPSLSSFDHIFKRKITDEYVDQIKIYESFIPKLLFSNINKRCPEITIAEIQSSEIEQLLLKYYKIKEDNDNKWLSRLFTFAFESIKQWYHNEDYDFENVLSPHNFKIFSKSTKIISKLLFPLENDNDEDSPQSLFEGGLLDKFYSSGFSAQNELVGEIIQESIKPILNEKLVFRILEFGGGVGSLSLLVLEKINSLLIQYPNYQIDIEYTWSDISPSFITEAKAKFEKFNDRVNIIYKALNLEQPLIGEKQGLKPQYFDYIIMFNVLHVIKDVKYGVEQIYQLLVPNGHLLFIEPIYKSIVGDGIFGVFDQWWSFQDTEIRKDRCCMNQQTWYKLLKSVNFNDDIKMTPELTCFVIQAQKPSISNLSFSKSETTNYNNIIVFGNKDDSNLSNNFIKSIDNGNLQFISTIEEFNKMTKYISNESIIYFIKSIDELSVDNFVNITHEYTQINQKLMELNSKCKHVLITNDSTTTNYLSSSLIGAARYYHECPLELFILNFDTPSIIENQNLFKTIEPLINSSINIQREFIINNHKVYYERIKNETKLKSIFKNSSSFESLEQVDNFMISLTPNLEYKVKVKPTSILKENEVEIKVMSTGLNYKDYLIYAGLVESVEPIFGIEFSGIITNIGSGNKEFKVGDSVYGTGKSTTSSHIITDIDVISHKPSNISHSEASSIPVVYLTSYHSLYNIGALKNNETILIHSATGGVGLSTLEILKWKGHSGLIFVTVGSNEKEEYLRENYGDMISGIYSTRNKNFVKQIKSKISKLNPFGKSGVDFILNTLSSSDYMDSNFKCLNMSGRIVDLSITHLNSNEFTDNKKFKYNYGYHNIELQYVDKKIIKSTLSIISNAVSSNDLQLIPITEYSIENVKDSIEFINERVHMGKIVVDHENQDSIINELIEKQKSIDKFDQSIFKQNYKLEPSLLGKNILITGQSGIVLEILKWILRNSENNSIDNIIILSKSSIKWEMELLINKTKLLNSNSINSMGNYLNKIKFHFKSVDISDSGLTDKGIHELLIENPDINNIDSIFHFAYTQATCNSDEVDLHHLTQSHSAKSMGAINLHNQSIKRNWKIINFIMSSSITSKTSSANQCGYISSNNVLDALSKYRISIGLPTICTNYGLIQSTGFVSRNESVAALLSGEGLLPISTNLILGTLDLQLQNQAQSSNLILSNFNFTSLNGLPQKSLISKFDYQININEENEKSKSLLKDDNVELTVDQLITFKISELLSTDILKLNKDIILVDYGVDSLVIIQLKNWVDKEFSIPNALTIQQVQNSTINSFIQLVKNSIDKKNKK", "length": 2552 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54EN3-1", "protein_name": "Alkyl transferase", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSNCSNNSENCNINDNKKKEENVKNQNSNKNSNNNNNKSNIESIILNKKSKFSSEKELDEKENKDLKDLSNNKPINIDEYEGLPRFENEQNARSKSSLWSKLCDWMYDQNFKIASSTLKNGPIPKHIGVIMDGNRRFAERNHLETKEGHKKGFNTMLDLCQWGLTLGVKIISVYAFSIENFKRSKSEVQDLMELANNKFTEMISKSHKLQQLGVRIRVVGDHSHIPEKTKSILAKAVKSTENNTKALLNICLSYTSHEEILHSMKILSKGVNQEKKIEIEDIDQDLFENCLYIKEDLDILIRTSGEYRLSDFMLWQSCFTNLALVNTLWPDFSFFHFIYIIFLYQFNSKTLKNEIQNQYKFNNNNNNNTDNNNNLKENIKNLKSDQRVKEFINHLKISEEKLFDEFISKYNEEEEEEEEI", "length": 420 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54F52-1", "protein_name": "Saposin B domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKLIFIVCLLLIFNYFIGISFGNKQINSNQQQQIINTDKNYNHNKNNKIIVSHNKNNNNNNNYNEIETENLGCTFCKYLTEKVEEYLQANSTEKEIISYLDEECELLNSPNLVLTCQNLVQQYTPIVIELIDNNESPSVICENVNICPTSSSSSSSSSIEEEIIKKLNIDDNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNEEEEVNTCEICNLVSNLIEKYIKINNEVDEIRELIENECELLSNSKVSSCYSLVDQYFEHFYVTIENNYSANEICQLFQFCPIESSSSSSSSDIINNIPLQDSGCTVCTVLANYAYKVQANESIPEIIGSMDEICNKIGAWRDICNSIMRSGGQQLVEDIVNKGEGVYTACSNIGYCQSSSSATGTSGFSSGGSGTSTGGGYSTGDFYYKPLK", "length": 416 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54GT5-1", "protein_name": "Endoplasmic reticulum junction formation protein lunapark", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MGNLFSKKNGFEKQLLDMETKILNLEDKLSNSRIFHQKVLHKIVLYSFAIEFFIILFTYVKSRSLESIPEKLFCCIYLVLFPIFILILTKVYGFVYKYLIKKNEVRLDSLKTGLQKKLDERKRETDYENTQKLLDRYEKNPPSPTNKPLGPPNLNNNNNNNNNNNNNNNNNNNNNNNNTLGNSMRNRNQPFNISSQQNQQQQRMIQPQQLSPQQLQLLQQQQRLSQQIVPSQQQQSQSQPQQQQPILNQPYNINNNNNNNKPPPPIQLPPQQSSQYIGNQQRLPPQQYQNEQKSKWWLDKLVDYLISDGPTHGSPLICSNCHSHNGYVPVEELSNIQFRCRVCKTFNQRDSVNNSTTNDDRNNSQNTGSNQQQSQSLQDQQPSIEEIDKNFSVTEQKNETNNENYSDSEKQLEENNNNNNIDNDSGSSSSQNTPNKKKGKGKGKGTPTKKTN", "length": 452 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54H60-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MLDFFHLKDVDEFFRLLEKKNLQNLDNQIDGPGNLNWRTTYTEKDFSKVPKFRGIIHIVQIRDLGTKIHRDLLYEIMFEKLLDIARLNNESKLLKNEIQDLKTKLDEYHNNNSTTNTDLIINSFINVIDTTTTTTTTKTTMGATSIDKKQSEGDSIDKSIELDFFKIKSDQSQQSSPSHKLEEKQNQVNNITNEIPQESIKTVKQQTQTETNQQTFSSTSPSHQNEEKQDKQEEVKQEEVKQKEGIQKEDKKEEDKKEEGKQKYGEIFIIEIPQEEEKQKEEGKQQDGENFIIEIPQEEDKQKEDKKEEDKKEDKQEEDKQKEEKLEDKQKNGEEFIIEIPQNETLEIKVDTHPRSSNDDVSTAEMEVEALKTPLFAETTFVTKQQVITNKKLLVYKQSDFFPNMTTLLQSRLKDVTVQEVKDLTKIGLNDNSYSVGDFENVFVLYAVSCMGARTDSERDAFKIKSIRSIIGDKVPIIYGVFMIGKNGPTRIKVEHTQTSISITHSMSDIGRNLQNNENLKQLQSFLQQ", "length": 529 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54H72-1", "protein_name": "Tudor domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSNIDFEDYEFYDDSDFEINTVDESVMTYSSVFDFLRFGKIPKFDTQTKMKHFKDNISKYRIESKDILHTNVDSKILRRLSEIPRVEKIFPDPNTLQLEVFKPNHELRNSNGELLSKHRPLQETLKLIEKQYYWECKFIHTSMEVDITKLYSFCDLCSQSSVSRDMDIDSNDEDKILEQMDIVEKSFSNDRNNNNNNDDNNKSIDEKDKMNICGIGIDLEAIKEGKLFEDELAEALGFPEYNSSVDNSFNSSVNNSNLNNSSLNNSLNNSKNNNNNDDDNNNNNNNNNDDNNNNNNNNNNNNNIISNIDNNNNNNNNNNNISNIDNSNNNNNNNNNNNNPVNDDFSFIIPKDYQSKNHLNDNENKDDEKDDDKDDDKDDDKDDKDDDKDDDKDDDKDDSKDNGYIKTNVSLSSSSSSDNERDDGDSHSDKSVDNDENNNNNINNIISDCNNNNNNNNNNNKINGRTFTSRRTRSDSNTSNSSVGSYISNSSKSSANSYDFSSSDQDYKSPNSPTVKKTRGASLVNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNINNSILKPKLKSKRASASTAINSFISQFITPKHPPKSSSRLKRANRSNDSSDSGDSSSNNSSRSSSDSSDNENNNSYYLPIQSRRSTSKQILKDHLKSPTKKPRRIIEEDFYHVEEKKSPTSKISTPISRSASYNFGRSSPGSSPGSSPSLSPYSSPPQSPPHVYNHNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNYNNNNNNNNNIRSILKSPQSPSISPIKTPRRSPQQQQQLQLQLQNYIPMPTKTKTPTKAPYVPNYALAPIEPKPTQKTPVHVFGGNQLSVKKRQTIEDMITEVLKMNVDTAALKLPLPKVGQHVEGKSNMEDYKDAWFKGVVKEVLPNDFFLISYIDGGEEELSYTRLKPNLTSELEPLKLEEIVVGGEYLGSYRNFYYNVYVLEILRHSIRVYFADLEMAKTIKYSQLYLLSSFVKR", "length": 998 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54HE0-1", "protein_name": "Conserved oligomeric Golgi complex subunit 5", "gene_name": "cog5", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNNNNNNNEGVSSSSSSSSSPLPNISSPNLISNSNIENDIEIKKKSNNNNNNIFEGDNSHIYNQFLGEDFNVVHYTSNALKVSSISLSLNTLTSCTRELGQELTENITTNYDDLFKLANNIKELDQLTDTLKLGVSNLEESIQRMKNDISEPYNKVKSHIGQLKRVQDSCELLRKLIRYIQLVKKLKNHLQAGSRDLSKSAQCINEINLLKKDSDLTGINIIDSQVVWIKTCSDQIITISSTLLYQGMENQNQTDVANSLQVFHNMTILNEKVYSIVNLTTEKVIKNIKALLNVNKLIADLPKTTITNNINNNNSNNNITTNNNNNNYNNNNNNNNNNNIISTSTDKSIWLKFESLIDTLYSSLIQILHLQRVLLKIKDPLTHKSLMEVLLIKQHQLQQQQQQQQQQQQQQQQQQQQQQQQQQQVGTTSNNTQPILIEMISTLFWKSILKVLENNLLVAAKSSNIIENTFIREYPKVSKFFLDFIKKLQNYIDIHQMDIQQQFMIVLSNINQIIGNNNSNNSNSNSNNSIESSLSTSSSSSSSSSSSSSTTTTATTSLILLSADDYKLSLFKSIGLFEKAYLEYSQSKMSTIVNGLFPQSTWSSRSTLPVIPNGKQLVDLSKTIWSEIEWLVGNNDRQLLGKLMLVVSKVIDLFSSKIESMVQPPGLIVLNSNIGSSSSTGGVNNNSNSNNNNEIITINENSKPTPSQTVNTLLFNVSIQLNSSIQSLLTSQPLERESIIVIEKSLNSLITICTNIITPLMNSFFTHIEQIFSTIHNEDWYNEKTTKMLINKSNQTCSSYMESFKTLVNYFQNQYLMRFTPCQLLNNQIKSMISKIFIVYLKYCSLLKQPFSENGKLKMVNDLTHLEFAVTPLLVSGGIKEIGESYNLIRNYKQSIFN", "length": 898 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54IX3-1", "protein_name": "Probable polyketide synthase 26", "gene_name": "pks26", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "METNNNKNIQEDIAIIGFRIPGCQDNTPSELWNNLMNKFSGVGKTTERWSDNYHLSGDINNGNSGLLPLKEWKKFDPAFFGINPTMVSTIDPQQRILLKCTWEALEDAGIDPIKLRGSNTSIFIGCSTGDYLDMVKSNNEIQTNLFGSVNHSLSNRISYCFDFHGASMTIDSACSSSLNTVLLGCQSINQGKSNLCIAGGVNFILDTTIPTAFSFLNILSKNGKCMTYDEGADGFVRGEGAGLVVLKSLKDAIKDGNNIYCIIKGGNTNVDGNGNADKANFFQPSKQSQSDNIKLALESIKKKSMLDIDIDYVETHGTGTPTGDPIEVEGISKVFKENHSPENPLLIGSLKSNIGHMEAASGVTSLIKCCLMFKNKSFAPNVNFQKINPKIKLDEWNIKVVTEAIPFKKNKITSMVVNSFGVTGSNCCLVLTESINNNNNSNVDKITKNEKEYLIPFSANSNQSLKNYIEEVSKIDESLQFEDFVYKQLSNKSTSLFQRFVVTSKDWKELKYKLSQPLPLKEISSSISVKKPNPITVFVFCGQGSQFNKMGLELYNNDKNFRNYIDRFDKKLLEYYGYSVISKLRSIDDNDLITIHDPIIAQPATAILQISLFELYKHWGINPSFIVGHSLGELPMAFCSGMIDFDTVCYLLYHRSLAQSKTNGCGKMLSCNISSEEFVKNYSPRYPFLEIACYNSPNSIVVAGKESILLELSKEFKNSGIFCAMLGSLSSFHTSSQLEVKDHIYSLKFESKEPVIPTFSTVTTHLFNSNKLYDNDYIFQNIMKPVLFNETISNLYKHVENNQLGSEMIFIELAPHQTLSFYLKQLIPKDSNYFSNSNSITILSPLHKKKNDYLEIQQTISTCYCKGYDVNFKSQILIESKTNISNKSLPLYQWDDKEFWKDLEKQKRILQGPPMDTLGFSNEKSPILKSFETKIDIKKKPFQYLKGHIVKGKIYFPGVGYIENLLKMYPSQDIDIDSMEFEAPLILIEGIVTCLQSNVYKIGKNEFKVQFHFQDQKTKQWIQSSFANYHLSHRDDFDPTTNKLNIQNLISNNCNLTKLSKNQFYNFIKAKAGLSYNGEFQGVEKCYLGDNCSLVEIPFDTSNQDVETNINMIPILDSCLHGVHILYVEQCQMVLEKIEGLKYYSSTLILSKQKEQQKLYVFTRIENKDLINNSISASIIVMISDGTVFFEIESVSLKSLIPLKDPISIENPTDELFSSYLQSIDSLISEPSSYKSIYKRNEFISSGMSDLSRSDYQQFISTLLYTNLIKRNQSIESDLRNQIEFEEIKAKYCKNSKFERLFTFVIETIKQYDGINGNLNSWNEGNIDIYKILIKSTRIISKLLFPLQGEDTTIDTPQSLFENNLLDDFYNINGNTVIQNQLVGEIITQSIKPLINEKMVFRILEFGGGVGSLSIVTLNKINQLLEQHPNFQIDIEYTWTDISPSFIPDAKKLLSNIKGVTIIYRSLDLEESLIEKQLLKPSYYDFVIMSNVLHVIKEIKFGIDEIYKVLSPNGQLLFIETPYRMLICDSIFGVFDQWWGFTDTGIRVDRCCMKQKTWFKLLSESNYQDIIMSDDIKDCCFVIQAKKPSISSLEYKLKIDSQENDKIIVFGENDTFMKYLENKSTKQIIKIKTCQQFSDLITSNSKEINNQSIIYFIKTLNQLLIENFKEITLEYIQINQLLLSSGLSCKHILLLNQSTSENYLGSSISGAARYFDEFPPLKLYSFDFDKYSLNNESINIIDDIIEPIIKSMNNSNIRKELLVRNNKIFFERYKQEKRIKENYKSTSFENDKSLFVHLNANLEYELKSKQVKLKQNEIEVNVKATGINYKDYLVYTAMTPSELINHKGESNPEFGHDFSGIITRIGDDDGDNDNEFKVGDQVYGIWFNTTASHIIVDKEFLCHKPSKLSHTIASSIPVVYITSLYSLYNIGNIQNDESILIHSASGGIGLSALNILKWKNHKSHIFVTVGSKEKEKYIHDTYGDFITGIYSSRNKDYLKLIKRKLTELGSNKKGVDIILNTLSSSEHMVSNFKCLNHRGRIIDLSITHLNHNEYTCNNNFKYNYGYHNVEVLFVKGDIISKLLKNITSAIENGSLSTGIPIIEFNDSDCFNAIEFINKRQHIGKIVVNHNKENLIQELIKKTNLPIIKSNYQINSDHLGKNILVTGQSGIILEILKWIVKYSTNVENIIILSRSSLKWELELLVNKNKNKLNFIYKSVDVGNSLEIEKVIDEILMENPQINNVDSIFHYAFTQISCKEHEIDQVHLNVSHQAKTMGAINLHNQSIKRNWKLINFIMASSAAGLIGSTDQCSYVCSSNVLDTFSKYRKHVLGLPSICINYGLIESTGFVSRNQSVAVMLDGQGIRPMQTNQILGSLDLFIQNPSKSTNIILTSFNFNEFATGNLQQSNVHKFDFQFNCCLSQKSKLMANNQASENPVKDLLINNICELLSIDESKLNIDIRLIDYGSDSLTIVQIKNLIDKNLLIPNLISIQMLQNNSISDNIKILTDSYNKKKQNEQNELKNIKVGSFTKK", "length": 2531 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54K45-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MTKILYLIIYLTLTIVKGAPLYNCKKLNCSSMNTNCKVFGCSPMFGCFETSKCPQSNVDICHTNHCDENTGSCYQIADTCNDGNNNTIDSCGPYGCVNTPVNPPEPTQSCEQKCNDNNPCTVDFCDFRGDCYHYETRCSDYDACTLDTCGEKGCEYRPMNCDDNNPCTADFCSMLYGCYHEPIECSVKVPCRTDSQCNRNNFCETYSCDLSSNICDYYTRDCGGNPCINNECRTGTITN", "length": 239 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54K50-1", "protein_name": "Phospholipase D Y", "gene_name": "pldY", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIINRLFIIIVLFFVNVNSKIISESTLNSCQGGTIQIAESIPLGLDISTNLSTHDAWMDLITNAQESIDLGFFYFTLLGGSDLDPVYGGQLGIDIFNAIVEAHSRGINVRIVQNEPSESFPDTETQTLAKLGIQVRSIDWVSLVGSGVLHTKLIIIDESSAYVGSANADWSSLAQVKELGIVLKNCPTMVADTEIAFQQYWNAADFTSLPINDWGSNYQALFNNTNMASLSLNNNNNNNNKNKNNDNDGSGTNQMYEMFLAVSPPQFQSTYRTGDIDALMDAINNADQSICITVMDYTPTTLYNDPNTYWPLIDNALRAAAFNRNVQVRMLISHWNYTSPIIPQWLHSLNQVDNIQVRWFVVPDFSTNPQIPYTRVNHAKFMVTEKQSYVGTSNWSQDYFTVTGGLSYNVFNNDFTNQLQSIFNRDWNSPYTQPIQNF", "length": 438 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54K65-1", "protein_name": "Band 7 domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNSIKKLSTTAIKFTKQTQRFNKRGFFKILNQYERGVVFNFGKFHTVKEAGFHIVIPFIQKCDIVDIRTFTYTLDKQKIISKDNINLTVDALVVFRIHDPKLAVTKANDCILLVNEMAQIKVCEILSHNTLDQVLHNRDKISNQIHDELKEALNKYGVTIEYLKLKDIHFDETIAKAIAKKVEAANLRDIKN", "length": 192 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54KF5-1", "protein_name": "Protein LEG1 homolog", "gene_name": "leg1", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKSNKTIFLILLFLINFNSIYSFNFKKEIKISNDKINLPTYNPWIFQDRFNLYSILINSTNIPVFGEDNSNNCLHGLQLQFEWQNRSGRLEINQGHVNTKSWWGDMNYYLSIIPYLSAMKMGLVPVVEIVSINDQRFCSTYEDCDQEVLNNWDNFFQQIINIRNNGSEGDDQQLLKFMWTAHIGSIDKATKLFTDSLLLLPKNELRFGNGWAHFVDVIATVNFNTNYSTVYHLGQQLPPIMLNSNDTHPSSIESFTKEQRNVVLTMYEINDLSSNNLVWNSFMYLLKKMTKNEICRNLINNEINIFLNSPVPTIIEILFDILTNNC", "length": 326 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54KK9-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MTEVPNQKHNDGGVGVTVGNFVKDNETNVNNNNNINGKGENDNNNNNNNNTIIDEPKLLNNNNNNILVIPLTTNIIDNELNQQKQHTLPLPLPPPPLPTQPQQITPPLPTQTQLPNNMLPSPRPIQQPKIRQQTQQQQAQMQQLQLQIQQEIQLQLQQQQQQQLQLQQKQNESEINGLFSPNFSSSSSSSLSTTPNMHSPLFNNNNNNNTTTTTTTTTTTTNSSTNNTNSSTQTKNASTNKISQDVIGVFDDTDTESEGEEYHSGRSIDFWNKDYKDIAWRCNWIDLQIRDLQYQSMVCDQLYHKVRRSKQKIIPDNKSLSSSIDNNNNNNLKSIPIETIDHSNNAITSSNIPYSNNEEEQQEQQQHPSQSIRTTSVVKLRKPRKLIRRPTVKLSAKQMTTDLEAHPLFTFHKGYFKFENAIKTNIINEMEIKYQEKEKPPKLLTLSEERLKQYINSNEDVDVVNLFATNESKRLSEKRRGRIPSDKKEKVSSHRLKSGDEIDGTSSSTATATTATTTTTTTTTTTTTNKKSRRSRREKKKEKEREKQEKEKHIKTKDEQKDREKKEKAREKELEKERKREKERIKEKERQEKERLKKEKELEKNKKKEKKLLKEKEKEIKEKKVKLKNQENIIEKDLTINNTTTKTTKSKKSSSKVKKSEQEGVKLENVEIEDEEVEEEEEEEEEVEDEEEEEEEEEEEEEEEEEEIEEVEDNEEEKRKEERRRRRRKRRILRRRKKLRRKQRKRQLFLQKQQQQQLLQQQQQQQQQKLLQQLKKRDESNGLSYKEIITPEWRDISSFANNDPSLPSPLLLSNPLLAQDIKNITTTTTTITTSEPISKFSTITEEELLIRQTTNGIDGTPMNGIGEDSESSGSEIELDEDAMKIIHARNEIEEKRRFFNTIKQIQMENPVPSYKRKKESLPVEFVAPTVEELLPSYHFNKKSIKLLGKSWNGDFEYYSSSDEDDYDDSDDYDSDDDNDDEDDDDSDSDDEDESDSDDYDSEYDSDLSDSDDSESESSDNELDGLYSSESEINHNSSGDEDEMDVELNNHHIPSKNSKNSKKQPVNNNVNNSNNLNGSSGGGKINSKPSKQQPRNSKANPPSKQQPTPLKQQPTPLKQQPTPLKQTTTPSKATPSPKQQSQQQQQQQQQQQQQPQQPQQPQQQQQQSPKPTPPLVSTTPPLSSVPLSPPTKTIRSTRGVSSLSNSTSSLPKQTNTPPISILSRKRNQSQSSVTDAPLSPTTTATTTTSPKPTTRRKGKLQETIPVEETKIIEETKPFEETVPIKENSTTTPLKRTRRQTKQQLVNGETTTPLTNGDNHVEKTDSNSTDVKVDPTSWWGDKQYKIQPVMEATVIRFKRVKNDDGDDDDQIQNNQKNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNINNINNTEDLESKIKETKSINIPMEISTNGNDFQMKEKEGE", "length": 1472 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54KU3-1", "protein_name": "Probable polyketide synthase 25", "gene_name": "pks25", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MDNSYLNNPQFDINNGNKEVTDDDNNKNNQDNLVAIVGVGFRLPSGENERNNTPQALWNNLINGFDGVVKTSERFNDNFFKNHEIANNYSGLLPLDEVKSFDPLFFGITPNEAQTIDPHQRLLLKCTWEALEDSLIDPISIKGTDTSVFIGSSTNDYLTLNRNEVKSNVFGSMAHSIANRVSYCYDLHGNSITLDTACSSSLNAIALGYDSIKNKKSKMSIVGGVNILLDPYPYKAFSILNMLSKSNGRCKSFDASADGFVRGECIGVVILKNLKDAIKDGNRIYCTINGASANVDGIGYSDKSNFYSPSSISQSENLKNAIQSTNGTVKPSDIDYVEAHGTGTPNGDPVETEGISKVFKDTRSTDTPLLIGSFKSNIGHCEAASGIASLIKCCLMYKNKCFAPNIHFKTPNPAIKFKEWNLKVVTEPIPFNENKNTSMIINNFGVTGSNCCLVLSQFNNTNKQKQQMKTKINNYLIPFSANSVESLKKYQSLIINSKENELKYSFEEFVKNQVFIKPTSLYQRSVIVAKDWNDFNNVENQVKYQTSSSTSSNITITNKNNNPITVFVFCGQGSQYNTMALELYKNEKVFRNSMDMLDNKMKNYFGYSILEKLRAIQDSDKRSVHEQTMAQPSTVIIQVSLYELYKHWGIKASFMLGHSLGEVTTAYCSGMIDIDQLCYLIYHRSTLQIRTNGLGKMLSINISSDEYKTNYMSRYPTIEIACYNSPSSIVIAGNEQILNEISKELKEKEIFSAMLGSLSSFHTSSQNIIKDDILNLNIQSSQPVIPTFSTVTSNLFNESTIFDSEYFFDNISKPVSFTQTISNLYKHIEDNQIGSNIVFIEIAPHPTLSFYLKQMIPKQSQYFRNGESISVYSTLHKKKNDVEEFQKSISQLFCDDAYDINFKCQFNNINSNIEAISNFNLPLYQWDDQHYWLNKSIEHKNNLIGPPISILGNSMQDSNPFIKSYQTIIDTGKDAFKYLKGHNVSDKCYFPGAGYIDNLLKLYPNQDLTINSIEFKTPLILSDDNGQFLQTNVYQTGKSDYRAQFHFKDNRTNVWVQTCTANFQLYNNGKVDKLNLEEIKSTKCNLSSIPWDKFYPHIKNRTGLNYKDKFQNTIECYLGDNCSLTEISLELPENFHDQESFFNTPILDICFHGSIVLIKDNCKLVLDKIDGFKLYTSNIPKNRFDHLSIFVYTTMKSTKSNSYNSTYTVMLEDGTVILEVENLICTSLTPVKDPLLIEIPTDMYYTPYLQSKDSQIQSPLEFKSIYQNNQDNDSLLIPNVVLETIKPLINEQMEFRILEFGGNNLSNSTLLLNSINSLLEENPHYEIDIEYTWSDNNSSILKDAKLELSKVDKGYLSILYRSLGLDVDNSLLEKQKLNPSYYDLIIVSNISNLTKDIKYSLNQIYQILTPNGNLIINEQQPNNENNENNEDSLKNLLVNCNFNSDIMMKSSSVSDSDIKSIIIQAQKPSLKLQPKTINTFDQVILYCNQDEQFQQQQQLINKFESHYNNNCKIIKVSTIEEFYKLSTTITNNSIIYFIKSIEQLTLENFKSITFEYVQINQKLYEFKSKCTHVLITYDSQSSNYLSSSILGAARYFDEIPTLQLFTFDFDKDSLINLDISVIDHLIDPKQNTLIEFFIKKNGKVYFERFKKGLKKNSFKSESYHQITNEQEILISKLDENLDYQLKSKDSILKPYDIEVEIKATGLNYKDYLVYSGLIKLKGDSVDFGLDFSGRVSRVGIKSSKEFKVGDEVYGIGQSTSSSHIIIDSMHACHKPSKITHVQAASIPAVYATSIHSLYNIGNLREGESILIHSGSGGVGLSALEILKSNNHSSPIFVTVGSEEKKQYLINTYGNLITGIYSTRDTNYQKQIKNKLIELGYETHGVDLIINTLSSEFMDSNFKCLNPEGRIVDLTITHLNPNEFIDNNKFKYNFGYHNIELYYCEKPTIKKLLQSISKSIENNTLNYLIPITEFSNSNIKKAIEYINERKHVGKIVISHDTDITNKLIENQPKIDYSLLKSNYKIKNLGKNVLVTGQTGLILDIINWIMKYNSTVENIIILSKSSMKWEMEFLINNNKTKIKFYYKRCDIGGDSDSINKTFDKLFTENPTITNIDSIFHFAVVQITRKVKDIDMKSLNISHDAKTIGAINLHNQSIKRDWKLSNFILASSILSKVGSLDQCGYVSACCVLDSFSKYRLSIGLPALSINIGAMGGSGMVARSELVETVLNGQGYNLTSTNQLLGTIDLLIQNPGQESNNLMVGNFNFPVFNNFKQKIHQKFDFIFNALDSNSENGDGSNIKNSTNIKDKFLNKVSEFLSIDSSKINNDIKLMNYGADSLITVQLKNWVDKEWSPNLITIHQIQSNSIGMVCQIINDNFEKKK", "length": 2380 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54KU5-1", "protein_name": "Probable polyketide synthase 24", "gene_name": "pks24", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKQNKINKAEILQVDDKHVEENLVAIVGVGFRLPSGSIENERNNTPQTLWNNLINGFDGVVKTSERFNDNFFKNHEIANNYSGLLPLDEVKSFDPLFFGINPNEAPTIDPIQRLLLKCTWEALEDSLIDPISIKGTDTSVFIGCTESDYHNINKNEVKSNVFSSLNHAISNRISYCYDLHGNSITLDTACSSSLNAIALGYDSIKNKKSKMSIVGGVNILLDSYFFKAYSSLNILSKSNGRCKSFDASADGYVRSECIGVVVLKNLKDAIKDGNRIYCTINGASANVDGIGYSDKSNFYSPSSISQSENLKNAIQSTNGTVKPSDIDYVEAHGTGTPTGDPIEVEGISKVFKDTRSTDTPLLIGSFKSNIGHCEAASGIASLIKCCLMYKNKCFAPNIHFKTPNPAIKFKEWNLKVVTEPIPFNKFKNTSMVVNNFGATGSNCCLVLSQFNYNTINNNINNHNNNHNHNHNHNNIKINNYLIPFSANSVESLKKYQSLIIENKEYESQYSFEEFVKNQIYNKSTSLYQRSVIVAKDWNDFNNVENQVKYQTSSSTSSNITITNKNNNPITVFVFCGQGSQYNTMALELYKNEKVFRNSMDMLDNKMKNYFGYSILEKLRAIQDSDKCSVHEQTMAQPSTVIIQVSLYELYKHWGIKASFMLGHSLGEVTTAYCSGMIDIDQLCYLIYHRSTLQIRTNGSGKMLSINISSDEYKTNYMSRYPTIEIACYNSPSSIVIAGNEQILNEISKELKEKEIFSAMLGSLSSFHTSSQNIIKDDILNLNIQSSQPVIPTFSTVTSNLFNESTIFDSEYFFDNISKPVSFTQTISNLYKHIEDNQIGSNIVFIEIAPHPTLSFYLKQMIPKQSQYFRNGESISVYSTLHKKKNDVEEFQKSISQLFCDDAYDINFKCQFNNINSNIEAISNFNLPLYQWDDQHYWLNKSIEHKNNLIGPPISILGNSMQDSNPFIKSYQTIIDTGKDAFKYLKGHNVSDKCYFPGTGYIDNIFKLYPNQDLTINSIEFKVPFVLTDGIGQCLQTNVYQTGKSEYRAQFHLKDEMNNQWINTSNSNFHLNSNDNYHEEKQKLDIQDIKQTKCNLSSIPWDEFYSLMKTQLGANFYGIFSKVVECYIGDNCSLTEISLELPENFHDEQSFFNCPLIDACFHGTVILYIQKNCKIVTDKVEGLRYYASNIPKNRDEHSSIFIYSTLKSSPSDDLLSSSIVVMLEDGTVIIEVDNLVVKSLTPVKDPLLIETPSDFIYTPYLQSKDSQIQSPLEFKSIYQNNQVDDGLLIPNVVIETIKPLINRKMEFRILEFGGNNLSKSTLLLNEINSLLEENPHYEIDIEYTWSDNNSSILKDAKLELSKVDKGYLSILYRSLGLDVDNSLLEKQKLNPSYYDLIIVSNISNLTKDIEYSLNQIYQILTPNGYLIINEQQQQQQQQQQQQQQQQQQQQQLLNNENNKESLKNLLVNCNFNSDIMIKSSSISDSDIKSIIIQAQKPSLKLQPKTINTFDQVILYCYQDEQLQQQQLINKFENHYNNCKIIKVSTIEEFYKLSTTITNNSIIYFIKSIEQLTLENFKSVTFEYVQINQKLYELKSKCTHVLITCDSQSSNYLSSSVLGAARYFDEIPTLQLFTLDFDKDSLTNDLDLFKTIDYLINPKNNIQREFYIKNSGTVYFEMYKKELKNLKNSYKSESYHDLSKQQDQLVSKLDEHFEYQLNSKQIDLEPYEIEVKVKATGINYKDYLKYNEMIKVNEAGIGFDFSGVVSRVGIKSSKEFKVGDQVYGIAYETSSSHIIIDSLLACHKPSKITHVQAASIPAVYSTSLYCLYDVGNLRDEESVLIHSGSGGVGLSGLEILKSNNHSSPIFVTVGSEEKKQYLINTYGDLITGIYSTRDTNYQKQIKNKLIELGYETHGVDLIINTLSSEFMDTNFKCLNPKGRIVDLTTTHLNPNEFIDNSRYRYNIGYNSIEILKVGKSTIKKLLQSISKSIENETLNALIPITEFSNSNIKKSIESIKERKHVGKIVISHDTDIIDKLIEKESMIDYSILKSDYKIKNLGKNVLVTGQTGLILEVLKWITKYNSTVENIIILSKSSLKWELEFLMNYNNNNNNNNNNNKIKYHFKKCDISNWNLINKTIDQVLKDNPTITNIDSIFHFAALQINKKLKDIDMNSLNVSHSAKTFGAVNLHNLSIKRDWKIINFILASSVVSVLGSFDQCSYVSACCVVDSLSQYRKSIGLPSFTINIGGVSDRGYLSRHKLVEAVLGGQGVELISPNQLLGTLDLQIQNPNMPTNAFVNNFNWPLFKSFKQKLHQKFDFILNPINVDNSISMENDTNQSSSSTNVKNKFLNKVSELLSIDPSKINTNIKMINYGADSLITVQLKNWVDKEWSPHLITIQQIQSNSIGMVYQIINDSLDKKKKEMDEKLLPITAKTTTTTKNDPNDKTEYKYIAGGDCCREFSIKFHYSSVVNFII", "length": 2471 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54LI2-1", "protein_name": "DNA replication licensing factor MCM2", "gene_name": "mcm2", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSQNNNNNNNNNNNNNNNNNNKRKTKTPSSVNHNNTKINEDKDLYNFIDKIRDKTDKSHLEDEYDEDDNTKDGKFNKVEDEIKNDIDSEEDDDDIIEDNEHLYDGDEDSENLSSEGEGDDLLDEDLQDQDEEEVLGDEDNHYEMEGLDNETYEDIDKDKKTEVDSILTKRDREEQKTRQATNRHQYRISSFLLDENDENMVDEDTENNKLLEKRKANLIKKRRETIRQQNDNIKKDYDGSVPSFKDGFVNSERYFEDGDGDDDDDDDDFDIGDNGQVVNLEEPDKDKCLREYVCMSGPRNEISKQFAKFLLEFKEKDGFNPIYQESIQKMCAANKESLMINFTHLCASTVFGVWVAEIPTEMIEIFDEVALKVVLRIYPNYRNIVKSIHVRITHLPICESLRDIRQSNLNKLTKVGGVITRRSNVYPQLKHVKYDCVKCKTTLGPFSLDGTFNDSKPPIGLCPQCQSKGPFVMNSEQTVYRDFQKVTLQESPGTVPPGRLPRTKDIILMDDLIDTVRPGEEVEITGIYKHNFDLKLNYSQGFPVFSTIIEANHINKKEDLLSSFILTDEDEREIRKLSKDSNIAQKIIQSIAPSIYGHEDIKTGLALALFGGTPKDVNNKHRIRGDINVLLIGDPGVAKSQFLKYVEKTAHRAVYTTGQGASAVGLTAAVRMDPLTREWTLEGGALVLADRGVCMIDEFDKMNDQDRTSIHEAMEQQSISISKAGIVTTLTARCSVIAAANPKRGKYDSGLNLLQNVELTEPILSRFDIICVVKDTIDSFKDRELARFVVASHINSHPDNQNNPENDYLNRATKQSPISQELLRKYIIYAKRIKPRITDIDKNKISQLYTDLRRESRAGGFAMTVRHVESIVRMAEAHAKMHLRDYVTDFDVNTSIRVMLDSFINAQKNSMYKNLRTKFAPYVIFQKDINQLLTQLLQTLARDFSNYHFARSGDIPDQINIPYDDFDTKARELGISDITSFFRSNEFTSNNQFTLKKDKSTIIYYRNK", "length": 1008 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54LX5-1", "protein_name": "U1-type domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKITESNNNNNNNKKDNNKHWCKYCKIFIQDNISVKNHEEGWRHKNNVTRFVSTQNRDKKYQERDQKEAEREINRIKNTGARSFREKDLSRVLDEKKHQQQPQQQPQQPQQQQRIFNNNSNNNNNNNNNNNNNNNNNNNNNNNSNNNNNYHQPQYPTTTTTTTTTNTTASNKNCDNADSKFKEIQEQQRQLLSNNDYYNYYQDRQQLIYDYYQNEGNQPIPEPPLNTSLYGYTESPLLKSRLDSSTDTLSSSSSSTIISPSHQKKRKQDDTNSPIPAKISKDECVNNENKDKSNEKENELNNNNNNNKSGEGEEGEESDDNDDDEEESGSGSESESESSEVDQSESIIGQWQTVDPIESAFGSTRKDSDDEKDKKDKKNKKDNDENKRDEKDYSDVSDADSEEESVNITKRAMANHKKPITLTNVISPTIPSTSKNFESVLSFNKSGVFSLNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNEPPQPTPQITLKFNKPLKQRNTRKTNIEDKQS", "length": 514 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54M95-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKLISILFFLFGILFFLKNVESASDVVCSFGYQACGNNCYSPSSGQKCYPGGVVCSFGYEACGNNCYSPSSGQKCNPGGVICSFGYQACGNSCYSPSSGQKCYPGGIICSFGYEACGRSCYSPSSGQKCYPGGVICSFGYQACGNTCYNPSAGQRCFN", "length": 158 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54N59-1", "protein_name": "G domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MDLDYAIIVLRHHLESNGRFFEISKDDVKNRVTIKNKLTQEERYIDFGEIQNFIQYDEFEYNLLANGFQENLSILKNSILPLTKAPDSCSSNRGKTIGNSSLLINKVNGLIDDDKDTIYLLLIGITGVGKSTFVNMVVNYIEYSNLKDALENATLEQIYTIASKIEIQDENKTHKFSLGDVEDYKIGSSVTQYSRQYRIKLPDGKTLCLIDAPGVGDPQGTLQDNKHFENILHEISSLKKLNAICILMRPDETRATVLFKYCLNQLLLHLHSSAKDNIFFCFTHTRGTMYKPGPTRAILEDHLKKMKDQSDIEINANEKTFCFDNESFNYLAVKKYNATAGIETNFSEDDEFDFGRSWDRSSKEFKRLLEEISKVQPHDVANTICINNARTMISNLAQPMSTCISNINTNIKLMEQQSEKLRNNSIGDESLLYIPVSVVIAEKLENSLLVCTKNGCSSNTDNPCNIDVVSPKWYSSLYWCDNINKMGTCKKCSNTGVLPCLWFDHQVVTIKETPQLNQLPGTDKKTIGQRTKSEIFNERELLVTKMGERKIQFQEEYDTIKTAIVDFSVFLWHHSLIKFNRYYEDYINMQIKQLENSENSQELIQKLNEHLSEYKASVEEIKHNVQNNKASVKTQKEIFATFDKLLTLPNVGYIIQNQIKLKQSSHYKSEAVEIDLFSKMKNKTKQIIK", "length": 689 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54ND5-1", "protein_name": "Multiple inositol polyphosphate phosphatase 1", "gene_name": "mipp1", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MMVKIKNIIILFCIFGLLSNVSSLSSSSSSSQSSDNNGNLSPIQDYDLEFLSKHLTTKTPYWILTKNGDSNSQGDGSSGNSNSNSNSNSNSNSNSDSSNEPPEQCKLISIDFIARHGSRMPVLNSIEKLKEMTTSILEYKEQVNQGFNWIFNYSVPYPSDIAGNLILQGQYEHYNISKRLLKKYPLFFEPMKYKPQSYSITSTAISRTGISASAFSYGLLQGTGSLGVDGFQPVFIETASLDQDILLRFFATCNQYVDQLKNGTLINKDEQTKWNQMVFPNISNEISERLGLSDIWLPTSNVISDIFEACAYEISINNISDHWCSLLSKQNILDWEYSQDLSNYWLKSYGHEINYQIATPLLNDILSGFDIYINNNNNGSSSSSSSSSSNNGDNSGSNGSSGSGSSTSTSSNDNGSTNNNDNKVEPTSILRFGHAETIIPFISLLGLYKDEQKLFANSSTEQIENRKFRTSVVSPYASNIAMFLFDCGSAADGFKILVQHNELPVLVPGCDEIYCDYQQFKSIFKQGIDNFKWNSYCNINDDDSGSSGGDSGNGNGNDSHSKKSSYFLAIFIPITFLVGGTIGGIFTYFSYEKIMQVKNRKKLTQYGNDEFISSPKSKSFSFKPTKFDSRSPLIQ", "length": 635 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54NT2-1", "protein_name": "SH3 domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSNKITTQFARTRQMLFTKTGHSEETIDVQYHYEKERTFSTEERLVKIQKNSKKLIELYKDLNKITTDIAQDACDLYDTQDPMWTPGSKLRDVATNNDKHLLDYTEQMAEPYTKPLSDYISQYKEARKRTEELTTRKVDMDRYKNEVGKLREKGAGSSSKAKLAPTEEKLRICKEGYDSLHEELLNDLPRLNEDKLIFIDYLVASLIKYQSEFHKKVSYEWSPLPSLTKHVDEYSGRDHQPVITSVERSAASINLRSDPVFKSNASIKMKPGAQDQQQYSTVDKDIHQSPNPSNLNLQKSTPNPYGGASAPPPLYGGGGSSTATALYDFTGVDSSELSFRAGDIITIHKSEGEWWEGELNGIYGFAPGSYLRMN", "length": 374 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54PW0-1", "protein_name": "Annexin I", "gene_name": "nxnB", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEYKEKEINTSSPSSPSKTQISNIENDSISEKAQEPISEKVQDPISEKAQESISEKEHIESNNVSEIIDLIKSGDQHLNNNNNNNNNNNNNNNNNNNEEENQEINYNDNQLSNEEIVEDVKNSNINNNNTIEKGNSSQNNNKNNNNNYHTEKCDYCLICKCYDYGEITHNIVEDSEILKQSIRYSYVDDTSINSILAHRNYAEKEAIMKKFNDKYNKSLETELASHTHQKYRRTLISILTEPSIYDTLNIENSIKTKNSNTLLEILLTRTNEQKELIKRIYLVKYGKNIEHDIIAKFSNGANVNGNMMKQLLISMLNNDRDSNSNQSLDMNLINTDSNRLYQAGEHKKGTDHEVFIEILSKRSFSHLSELDRVYENSNPKGHSLRKAIELEFGVSKSIKQVKISLLDILLFSKEPSKYWAEQFNRALTSGSWGINEIDLTRLTITQQHQASKIKQAYISHYDNSLINEVSSKTSFRYKKIILSMLTV", "length": 487 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54QB4-1", "protein_name": "Kinetochore protein Ndc80", "gene_name": "ndc80", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MHNNNLTYQQYQQQQLLIQQQQQQLLYQQQLLQQQQQQQQQQQQQKQYSHGRPSTLGLPSRKPPPMQPQPQPQIQAPIQLTFQQQQQLLQQQQYQFNNNLNTINNNNNNNITNRHSMVTPSTNLGGRSSLGPPSAMLTNNNNNNSNIRNTTFISNSGGNNNNNNNNNNNNNNNNNNNNNNNNNNNNIINNNNNNNIHTQVQPKKSIAPSKSNTISSNTTTTTTAASSSSSSNPSITLRQETRPVNDSKFQSQCLLRLQQFLSQSEKGYPRAITKDNLMSEINGLMKFLCLHIDPHFKLPTEKPEEEIISFFKMMGYRSAGFTKRVFSQVGNAHTRGHLLGAIIWMVELIEYDQIIRQMDSHIEREILNGNTIDENGNLTTTTSATNTNEDGNFNLTTQIFSKHVFKSYEAFLKGDDGNHVDQFLEEKFNEVNELIVKECEESMERQKKIKQEIVNLTQYITNDDIDQLNFKLEQTNQEIIATHDLINDNELEDQKLDQEIDQNQTHFQELEIQQKEHQKKKQEFESRIQIQQSNSVDAKRINQETFELKEELDKVQREQSRHDQLKQEKSKEIKQSINEIEKLIQSYKEICCKASLVTNDNLIIEKYRIIFTHTLNNNNNNNNTNNSSILNISNNIINNNNNNNNNNNNNYEEGIISISDLKLVIKNLQELNLEISQNISKIKQDLLKTSNLNDIQKESISDKELELARIKQKHDKQKNILKQEKQDQTFDITQREENIEQLKSSNKKLIDDGVRELEKTIQLLESQREEHSRLKIDLKQSSEQMKLQYLKRIERFISHRQLIGSQIFDTLRQMEELSLTQKILFPPPPPPPQLSQQHQQLMQQQHQNNTIDIDE", "length": 855 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54QD2-1", "protein_name": "Probable cytochrome P450 517A1", "gene_name": "cyp517A1", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEIINVFLFLIILFLVKDFVKKNKKIHTKSPSGPIAFPILGNVVQIRFWELFKIQEHELFGGYSKKYNGVVRAWFGERLFFFVSNYDVVKYFQKDENFHNRPSVLVPGWRYASSNGLGVMSSSDDKWKRAKSSVSQSLRVRTTKKLMEEKAIEFIDSLEKISNNNEIFYPKGHIQGYACSMLFKYMFNQDLSVESGMSRTIGNAVEHVFGNLSKLTAFDCFEIFSPLYDWFFTRRLKGCDIVRQIISSQNENHLKSIDPSKPRDLMDDLLIEYGLNEITKEDTMQINQICFDIFGPAVGTVTITMNWVILQLCNRPELQEIAYQEIKKAVKDDEYVNLNHKQNAPYIVAFIKETMRLCSNGFGLPRTAKNDQICGDFFIPKDAIIFINYLEISQNEEIFKNAKEFNPTRYLDESLPVPNIHFGVGQRACPGRFVAIDKMFLGISNLLLKYKLKTQNGEKIDDSIQFSVSLKAKDYGIKLEKRI", "length": 483 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54RM4-1", "protein_name": "Peptidase S8 and S53 domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKVILIYFIVIYLINISFSLKPYQQQQQLHNFNIIENNNNNNRNEKVIIAHPKIPPYWLIENEISNPNDLISFKILLKQNNLNKLNYLFEEISDPKSKIYGEFLSINEINELVKSSESDFNVVLEYLKSFNIGNIENGSEIKVFSDYILVETTIEKVSSMFNSKFSNYKNKNNGNTRNRLNGPAYLPKQLLNSIDFVTGLSEFFENNFKIENYLNNNNKNNGDSDSDSGSGSGSGSSNSYNGGLDDILITPKVLKSYYNVPNELIGKFENNSIGVIAFNDYFSMGALELFDEKFNITTTKDNLKIIGNDCLGKGCDQYESDLDIQYIRSMGENISTDFISFNDAQWILDYLHSVLLMEKPPLVQSISYGWAELLQCDVSNGCSTFGYDSKQYVDRTNSEFQKLALLGISVLVSSGDDGAPSMGGSSGNCPIDGTVYCPTGGCNHTKTMCPEFTIYNLNGGSDSGGSSDSYCFFPMGIASSGCTNILGDPSVLDSGMKIFSEKNKQCNLAIEYDRTNLPHVYSECECKDLVNVTFRNYHFTQYQFNENNGALFVAEYPSSSPFVTSVGATQFLSRDEKITTEVGCTILQGAKITTGGGFSSFQSQPKYQQYAISQFFNTSFNSLPPSFSYCPTNRGVPDISMVGHNYKIYSSDGNNKDFNQCPCKSLPVDGTSCSSPTLAGLIGLINDQLLLNGKTQLGFLNPLLYQMAIDEPRIFNDITGDSSNRCSRSYCCLYGWSTSSNTWDPVTGLGSIDFNLFLSYVLKLKGI", "length": 767 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54RX1-1", "protein_name": "Translationally-controlled tumor protein homolog 2", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKLYKDLIGNSHDDLLTDRYEIKVGDVTFEVKTKMITKDLNVVVNNNSLGGSISTTVDNNNSITLSTNLEDEFENVEAAGTFQINNLVEQLRLVETSFDKKSYLAYMKLYIKDLINHIKQQPSNSDNEKIEHIQKGIQSFVKTMMDGENFKKYSFFTGSSMDANGLVALMYYKDDDPTTPTFVFIKYGLLQVDV", "length": 194 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54S19-1", "protein_name": "PHD zinc finger-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKNCIVCSKVGQYPLNLVKCYECKSYYHKFCLQSTKIPRGEWYCSSCEIERKNKKNKKRKLDGAGKKNKKNNKDDDDDNDDDDDEGENDEDDEDHQDEDSGEEEDEEEDEEEEDDDDEEEEEGNEKNKIKKRKRIPINQSPSIKKRTKDIDSEEEEEEEEEEEENDSEEERRIQKRKNKIKQQQQLKMKEKKQREKLRKRRRRTRSSRKDDNDQDDDDDDDDNNSNNSDDNDQDENKNKQKRKRRKDKKKDDDDDDDQEEEEEEEEEIVTGKRKRRSLNKVQPNQHLNNENEEDNEEEEEEEEEEEEEEETDSSEEFLENLVCSSCNTGKDEDKILLCDTDNCSRGYHMYCLRYPITSVPKGDWICDFCRFGDISADLHSADDDEDGAINSQKEIEKQKQKQKEKEKEREREREREKEKEKERERERERREKEKKDALRSSFSNIPIPKINNINGSNGSNSNNNNNSNNNGSGVNRQSPPKVISKKSPQQSPKPLKSPTSSSSSTTSSPPPLHQQSKVTSKISPNSQQSIPTINSNINKSPPSQSKNSPPLKPLTPDLKKQIPITNITTSSTTTTATTTTTTTTTANTSNVATTTTLLKPSSQKKPTILSDKKQLNTSGTNLPMNGKKKEDLESSASHSILDMIPPNNKLFNNSIQSAPISWDLSGSQHKLSTSSSSLPNSNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNIKLQQQLQQQQQQLHQQLQQQQLQQQQQQLHQQLQQQKLKQKQIEEEQEKEREQKRLENEQKLLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQEFIDQKELEDKLLSQFDNQNLKSPLSLTSTTSSTLSHLPQSTFESSTILSNKTIKQKWKSRILFETDQICQCEIIQIYGMDFKVNPFQNNITSKTLELSFNQVSFDNLPKPIRDEFITKSSTPSTCLDIGAIDLPNSALLIFLPEIPNQSSLYHLIIHFIENRVAGFIDLSNDLSLYIYPYQTSIISLDLIGILIDKKSLSPPSLILNQQQKQQKQQQQEQEQQNQSFDIKNICYIGINHISMNKILTSQGKNYFSFSNFNELTLSSDIKNFDLVVVDNKMVNNQTINKEINNLMQLQPTTNNNNNNNDINNNHDTLLLVIKDVEFSKWLVSQKKFPNSLEIQKIFQQQILFKQSRCIFLLDNSIIIENESSYFVEFISSFGKFKNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSSNDWTIKISSTIFDELLPFGHQSNVKKKIDEIKRGINQQLIVSYDFSPMVPKQSSDFLLLALRIAHSKKYKQVFLITSNKIIQNQSKRYSNLNLNCLSLEGGIDYIKNINNKFSLKI", "length": 1361 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54S56-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIAKTQIKCTTIYAPAKSNERHEWYKENLTEEILHSDIITGDFNVDCSVDNNLNKYIKTIFDEFEFTEIKNGITFPRNKSTIDRVFVSKKILHLNPIVTTKEIKLKSDHNMVIIELKIPEYEQQKKGERLWRQNLETLKMNSTSLKINKTIKYYNKKFEENTSKWYKLNICEQWLKLKDEIKKLSINIEIRESNKTKNKLKELAEKLETAKDSRAIFLKEEINNILKEQVRIKQANQTNTHINNKETPSKYLTRRLKVQRKTNEIPQILDPSNNCLVTKHEDILEVARRYYENLYQKRECNEDTHHELLKTFNKRIDQKILDEINQPIEGYEIRLGIEKIQEGKAPGKDGLLPTFYKNHINEILPIISKLYNHFWNTTIPKDFKQGILITIYKNKGDPNNLDNYRPITLLNVDYKIYSKIINNRILKFLNKIISPFQTGFVPRRLLHDNIITLNSTIEIIKREINTKEDMEPIITFYDFEKAFDLFSHNAILRTLAHLKLPLKMVLTIMNLLNESETSVYINNSLSKSFTSKRGTKQGDPISPTIFALVGECMATTIINDRCINGVTKETIKILQFADDTATIAYNFMDHFLMNEWIKKFCQATSAKINQTKCSCITFKWNTRTLYTVIKSNERYLGFDFNNKGIKSKINTISDNIRAKLVTWNSTSSTYMGRLIMAKTYALSQLTFHTYINTTPQHNSIENNIVKFVFNTKSKNSLSLQRRQNNYINGGLNLWNLKTRELAQKAWLFERYLHQRVSNTPSSYIKLWEEELKNNNNNKTTTKQNQLQLHWQCKQAWTQLKTPQNKQTHYEHLPKLKKIYEDMMTTQSPEHNKFIPTPGQKEIMTKINSKHLPFKEIKKIINMKGRDLLWRYTLKALPKIYNMPCQQCGEDETSEHIFFNCKAHIKNTQEIFNYTLTKCGHTTHTWNVKILNHLQIALVANLIAIIFDKIWHKRNKLIHDEKEIIIHRQQVIRELIKTQRAAWDRTQAVINKTLRIKSKQRPEEQNKLDSLISLKLLQFSRQWNSPLHAIELPKHLKKYNNSLSTFYK", "length": 1047 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54SW0-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "NQAKSSTIQQPTQTQQSNINNNTAKPRAAPPLKLVITNSNPSLKQKPQSQQTIPQQSVPQQSIPQQTIQQSVPQQQPNQSQQVNVNRTINPQQQQQQQQQQQQQQQQQNINRTAPLPQQSNYKPQPGVIYQQQQQTQYRVGTPLTINRSPMVGMVSKQPMSSSQQQSQSQQNIQRVPCQGKCCAGLAVKPLVPINSITAKPPPYSTMGPRGPISGGFVRTSPTGAIIGPSPQQQTMSRAMVNSMPIQPQIQIKPKPSPLNNGGIPITTTTTTTTNPLNKSSPSTLTQSSNTLASSNNNITTSNSLSSSTSSLPTTSTTPTTKPKSKPRSKSNSNSQTSSSTTSSSSTPSTPTTNSTKNKENTTPNKGDDSGTDNEKSSLSNSSKLLPTAYTMDQVLPFNPNQMFLGPEDKYIKSATRTYHKIPTNPSVMSNNRGAEIPSSLEYILDIPIIHDEPSSKNNPTWGRLILDALRRLVANKKTTRITERLKLDNMYKDMDSRSNQDKLDWKNGLVNEAQLNYLLSFLSNTIPFPDTPEKNKNKYLSSSDSQIINSNDQSNSLNSNNSSNNSTTNNNNSSTTTNSTNNIINNNNNNNTSSVPNSTNNSNNSSPEQQDVIDMELKLEPDNSMNFPIEINMDSLGSYIDDSFTFDNSSYDDTATISSDDKNLPITTVMPPTTSTTSTPQTITNTIPTTTPTIISPPTITTTTTTTKTTSPPTITTTTSPPTITTTTSPPTITTTTTTINSITPTTSTSSTINSNTTPMLDIVIDPVISLELLDENHQQQQNKEVKEENVHSKQQPPQQQQQQQQQQQQQQQQQQQQQQQQQQQQEDFMIQVQTSDLETQTQIQQDKEEIQVKPIVDSKKSGNSPTQIQQQQQHQQQQHHHQHNTLTQGFEFGMMMDIMNSPSSTSSMKRKRDDVDQPINQINNSSMVVQQNNDFFSDFNTIEAPFSSSHHSSQLSFQTPFSPDIVIDSDFQNKKRIVS", "length": 981 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54T36-1", "protein_name": "Probable polyketide synthase 19", "gene_name": "pks19", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEFGNKEIAIVGIGFRIPQGKESINNGSVSHLWNNLKNGFSGIVETSERWSDNINLLGEVNNKFGGLLPLKEWSDFDPVHFAINPSEVPLMDPQTRLLLKCTWEALEDAFIDPIDIRGSNTSCFIGCSTLDYSTTNRDFNETSENYFASNVLHTISNRLSFSYDIRGPSMTIDTACSSSLNSITMGFQSIQNGTSNLSIVGGASLLLDPYVSKSFSFLNMLSKKGKCKPFDSEADGYIRAESCGIVILKPLSDAIRDGNNIYCVINSFSSNVDGGGLNDKSNFYSPSKQSQSDNIKLALKSANMKASDISFVECHGTGTPTGDPIEVEGVSMALNSSTTSTPSKPLLIGSLKSNIGHCEAASGVASLIKCCLMFKNKHYAPNVNFDQPNPKINFKDWNIKVVTEAIPFTNINEKPVSMVINNFGVTGSNCCLILSQFIEHSISLNGNNPSYPIESQQQIFLIPFSANSVKSLKNYEDLIINDNNLSTNSFKEFVKNQIYSKSKKLYQRSVLISSNWDQLKTKNKYFKTSNDKSSNITIKRNQPLIVIVFGGQGSQWNKMAQQLYECEPIFRSSMDKFNKELSKYYGYSVLDKLRSIKDDDIISIHQPIIAQPSILMLQISLFELYKHWGINVSFIVGHSLGEIATSYCSGMVDFQTVCKLIYHRSISQNNTNGCGKMLSVNISHSEFIELYSNKYPTIEVACYNSPTSIVIAGNENILKEISLDLKENNIFCAFLGSLSSFHTSSQNSTKNEILPLEIPSRQSTIPTFSTVTTNLFNHETTPFNSSYVYENIIQPVRFSQTISNLYQHIENNKLGNELIFIEVSPHPSLSFYLKQMIPKSSSYFNSVSVLTSTNKKNSNDLDEIHSTISQIYCLGYDINFKCQFNHNDDDVNSIRNNSTIILPNYQFDEQYYWKVDINFEQYRLNGPNVFNNLGKSMINYSSNNKSYESIIDINRNPFKYLKDHIVKGKYYFPGIGYADNIMKLYPNKDIVINNLEFLAPFVLKENVKHILQTNVYQLGNTDYRVTFNIKDNKANQWVQTCTGNFQLISLKDNNNNNNNNHSSKYNINQLLSECNFTTLSKQEVYKYSKLRSGITHLGTFQGIEEFHFGNDLTIARIQINYENFDINGKPVYQTFDKSFFNIALLDNCIQAITGFITNSSQFVFERLEGLKVYSENIPTDKLKYKNIYCQAKFISLEADSYKSSVLVLLEDGTKLLEIEHISFRSTLPLIDELLLNNPTNELFTNNLQCKDSLVNILSIDNNETSSSSGSSNTVTEIIKQTIKPIINEKIVFRILQSFSDSELSKQIIEALNQIFDNSLQEIDIEFTIIDNSNDKLPTLHDSSLIFKNDITQLKPSYYDIIINNNNDETIIKPIFNILSSNGLLLLIIEDDIGIRFNINNLIGVGFNENKIQKSNKVIQSQKSTILSNELTVVPNNKNDNIIIYCEKHSKYTNEFKKLISNNHTNRKQTTISNINEFNQLLPSITNDSIIYFIKSMEQLEMNNFKQITMEYIEINQQLLKHSLTCKHVLITIDSQIKNYLSSSIIGASRYFNEFPSLNLYSIDFDNQLSISSLLNKIINQLIENSNNHIQREYIIRNNSIYYEILKNEKNIKSNFNSNSFEDNDFMTLLDSTNLEYKLASKPKKLKKNEIEVKVLATGINYKDYLIYRGLVVIDENVSISKNPLGLEFSGIITRISDENKNCEFKVGDNVFGVSHDATASHVITDVLYVSHKPNNISHIEAASLPIIFSTCLHGMFNIGNFNIDDDEVILIHSATGGIGLATLEILKWKGHKSPIFVTVGSKDKEQYLIDNYGSFITGIYSSRNKNYVNEIKSKLNQLYGTTGKFNGVDLIINTLPNEFTHSNFLCLKERGKIIDLSITHLNNNEFLNFNNFKFNKSYHNIEFMHINKRVVSRLLKSISNALNENKVKLIPITTFQIENVKEAIEYINQRKHIGKIVLDHSCSNGSIGSDGLLNQLIESDNNEKNHTILKYDFKIDTKNIIGKNIIITGQSGIILEILKWLIKYSPPTESFENIIILSKSSLKWELELLINKTISRKDNNTKFHFKIVDVGDSIEMRKSINQILLENPNIDNIDSIFHYAFTQVTKEVEEIDIESLDISHNAKTMGAINLHEISIEKSWKLKQFVMASSIASLFGSFNQCTYVSANLVLDSLSRYRKSIGLPSTCTNWGTIKSSGFVSRNDSVSKMLDDQGFIPIPTNIILGSLDLQLQNSNKYSNLIVSKFNYDSIKKFASETSTFQRLDFILNSIKEKDNDNNGGENISISESIQMKFLNKISELLSIEQSKINTDIRLGEYGADSLTSVQLKNFIDKENKSNVITLQQLQNNTIGVNIQIILEQIKKLDSNETKGKSKKIIKKDSAPSLEYWRNEMKLDESIQAIKMNPIDFRNDSKVFLTGATGFLGVHLLSNLIKSPNCSVVYCLIRNKKSEPNPINAIINNLKHHKLYHFHNEFELSKVKVIVGNLASPLLGLSKLDFGFVSNQINLIINSGADINLASNYEESKVVNIGGLIELIKLSTTGDYQKPIVGFSSISVFFESPNCKEFDEETVIPTIENINNLPGGYMKSKVVVENLFREAAKRGIPSMLIRLPIIFSHEETGIGHDSDFFQLIIQSCYAVKKYPNIDKNILTSPIGWIGLNTIKMIGNEKCWNKSSSNQLNIYSLNSEVSSIKSSFSFLEKQYGCEMVEYEQWKNIINQSKILSCIKFKTFHSLDRLNGVYNLGHGFGVSKKTKELLQSMNSYEGGMVNEKIIQNHINYIFKN", "length": 2778 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54TD0-1", "protein_name": "Peptidase S8 and S53 domain-containing protein", "gene_name": "V4-7", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MISKTSLLLLLLSIVALASAISVQRVPIADVTSAPAHFVQNKLAKSYELVQFKILLKQRNLDILEEKFWDVSSPKSENYGKFLSKEEIDSIVAPSPKDVKVVVNWLIDNGLSKNEMIVHSDFIQVRTNVGKASTLFETSFAHYSSSRTALKRIRVVGQASMPMHVLAKVDLVLGLSDFIEDNKMSESMRATKKQVQGSTVSITPAVIKQYYGIPTGQIGVESENFQSIAAFSDFYSSGALQFFDQKFGIDSSTVRVKNVGQNCIAQNCDQMESDLDVQYMTAIGNNITTLFLSSGNGEWIIDWATAIQQYNPIPKIASISYGWAEVEQCEITNSCSTLGIDSVVYVARSNVELQKVGLRGVSVFVSSGDDGAPSFGAASGNCPIDGTKQYCPLGGCNHKSSQCPMITIMESNGTQCFFPMGSESNTCQSMLQNQNIVNGINEFVSSNSKCQVALEQDTQQNYHIYSSCTCDKLKPYSDSDAGFKIVGYSYDQDAGTLFQPDYPASSPFITSVGATQITDVTKPEIVCSVATGAIITGGGGVAITQAQPSYQADAVATYIKSGTLPPSYSYNATNRFYPDLTLVGHAYEIAVPNTLTSNTCPCALESVDGTSCSSPTLAGMISLINDKLIGAGKPTLGFLNPLLYQAAKEQPNVFNDITTGANNCNRAYCCQYGYTATTGYDAASGLGSINFKNFEQYVLSLN", "length": 702 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54TX3-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MFNFERIDHGSGKGTGIAIENRDTRKGHISINFKDDDGRILSIKYNSFNSINILLIYAPATISERNTFIINSKSLFKKYNSINHQIIAGDFNNNHDCNSFFGTELRKIIDQDMLLDTGIEENTPTFPRSMKRLDRIYCHPTLLNQNSKLVVHNTVFNKSDHFPITITIQTNRETTTTTTTKLERLPWTLCKEILNNKHIHDGLSELISKNKDKIKSVEEWTKFKNNVIRDYFKKEQNKIKKEKNKRKYVIHKLLGNSDIIPKMRKELNEEISRILEEERKVKAWDIKLKLHLHQETPSKYLTSILKSRAKDKSIFQIKDKDNKTISDKENIAKRFVEFYQDQYEEKEDNEETHKKLLEKWEVDVDLIKKLEIDRPIRIHEVTKAIKTSSIHKSPGLDGINALFYKYHINSIARILTIAFNDLLTNKKEIPTKFKEGVITTIFKKGDELNISNRRPITLLNTDYKILSKILNSRLLDITSKIINKFQNGFVPNRFIQDNIQIMKEVIEISNKRKNNTLITFYDFNKAFDSISHKSITRTLEHIGIPPKFTAILLNLLKDTKNKIKINDFLVNGITIRTGTKQGDPISPTIFALVLEPLLIDIINDNTIKGFTLPNSKSLKLTAFADDIATFTNSTEELMKINTKIQKYCSATSSSLNKEKTVMIAIGDKPHDLPFQESTVPERYLGLNFTKTGLNSKYNTLIQEMKNNLIKWKSQAITMKAKMTILKTYVLSKLTYHQYMDNLNEEQIEEINNMTRWFLFSSVKNTYTEERKYKTMMKIDRAYADWKEGGIKLWDIELRHIAFKIWYMNRLLHNNYNNNNNTLQEWYMEQLSRKKAHTSTLNDMCRHWGVFRVKFYQNHPKINELPDCIRNDNDEPLKLKEIYELMIKDRHPTPRRTEWQKLWAVRYNTAIPKVFININSISHQKGRNTLFRFFSRSLPGINHERDTRCKICGHLFRDPYSHLFTLCQDILDIEKTIISTVNKLSFIKIHRWSMDTLDISKYNRTERIFPNLIGIIAHQLWKIICHKLFNTDESKPEPKFEQKVIETELLNLIETEKFITLKKIKHDEAILKNTNQDLHKYKFNKAWQTPAAPNPLPI", "length": 1097 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54U20-1", "protein_name": "Peptidase S54 rhomboid domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIYGDTREFRNIHFHLNNIRIVGAIFGQDGFIHKKIPLATKVISIICSILFALSLVAPSMFGSYKTCLSIESLTNSFLDNLYRIILSNFAHLSIYHIVYNMITFLDLAKLERLTFGTLKYFYLLFLFGIITNLICLFIYFIGRNNVCHLGFSGVLFALIYIESNSSGRDVFLFNAVKIPSKLYPWAMLILAHVFVPRSSFIGHFSGIVVGILFIKGYLDIFILSNQKLSEIESSQLMNIFTTKNSYFPIIKFGGSRRSYNTDRKSLDGLFFELKNLFNPQQQQQRQQQRQQQQPQSPQPQQPQQPQQQPQQQPQQQPQQHQRDNFRNDNNDNSNNYDEYDFSK", "length": 343 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54VC1-1", "protein_name": "ABC transporter C family member 15", "gene_name": "abcC15", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIKKIKNIINKIINFFSTIYILCKIYLYYNIKNRYEAYNILSVYGDDDFFNKPCPEDSSNWKDKLTFKWVERIIFVGFFRAPLNLNDISDLPSSLKVENTAPLLKDIIFNDSTIPLIKHIYSKFLPRNYIATGLFVFVSVFSFITPLILKNFLSYVEKIDEQKHIYIGIIQCFLLFLSSFINMASQQYSYWFGFKTSLEVKGALETIIFEKMTKLSNLSKKNYNIGSMLNLMSVDTDFFQYFFCHYYIEIFLFPIQILSLLGFLIYVIGIAGFVGFLVMLITIPLSSFLGTQISKNLSTSMGYADTRISLTGELINGIKFLKQYAWEKMFCERIEEQRKLQLKYLYIRIIYWVLVQIVTQASSGLVLVSTFTTYTLLGYEVSLEIAFTSITILQNLRRPIESLPDCLHKFISLIASAKRIETFLQSSELQNQPFIHNQSGLNDILIRNINFNWNEHNLKLKNNKNNQNNNQNKRSIILSSGEQFEITNDFTFDGIDIQDDNYDYEKEYKINYNNNEEEENFMTDCLLKIKPLIKDRRLQQQQADYQDLLSINLPPPPSENVDFKAPKGLLTIISGGVRSGKTSLASGLLGEICKAVDKSSPDSVNSILSTIQQPFLQSTSFRENILFGKPMNMERYIKVIEACCLAPDLLAMGEGKDLTEIGERGINLSNGLKHRIQLARALYADSDCYILDEILSSVDPEIANYIFQHCIKGMMKGKTVILVTHQIQFISSADHVVVVDNGVLIQGTYLELLRMGIDFEMILKEKENRIEKQIVQLQEDEDYYEEVEILDFTMNNNNNNNNNNNNNNSNFNGNNKLKRSSISLPKGISIESIISKDFDQTTIEKAKLFVQEDRNKGDPGWIIYKKYIRMGSSISFFIFTCIIYLTSQIILLLSDYWLQSWASHDRLNVSEPTDVHYLLIYLAYIGGFVFTLGVRYLLIAKITFGSAETLHRSLLKSIIRAPLTFFEQNPVGRILNRFGKDISDIDILLLDCFSDVLYCGACLVTSIGIIIYISPYIAIPFVILIAINYIFQLFYNYSVLELKRIQSISRSPVYSLLSEVYNGLTTIRSFGQQERFFNMMKDNININLRVFFYNFAVSRWIGIRVEFLSAIVVLMSALFSIFNDNPGLSALGVTTALGITFNLNWFMRQFGELESRINSVERVQSYISIPKEKETNEDEFIQTGFIWPSRGEIEFKNVEIRYRPNSIATLRNFSMKINAQERIGIIGRSGSGKSTIGMSLFRMIECSSGSILIDGDDISQIDLKRLRSSIGIVPQDPFIFSGSIRLNLDPFDQFTDNEIWEALSKVKLKKMVSTMPMKLESLVQGGDGLTIGNKQLLCLCRAILRNSKIVLFDEATNSIDFQTTRLIKQTIEENFKDCTILTIAHNIDTILDSDKIAIIDEGELIEFDTPLNLIKDSTSRFSKLIKLNNNQKNKLN", "length": 1436 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54VG9-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKSIIILSFILSIISFSNGTIVKCTSASCSSLNNNCVNHYCNPRAGCYGIDKCVRIDACHIVSCDLNNGSCINTKANCDDGDPCTDDFCHNGYGCFSLPNNKHPSVICQKNCNDNNPCTDDFCDFTNTCQHTLKNCEDNDFCTIDSCGPNGCVHTNISCDDNDPCTSDFCSIMYGCYHEQIECSIKVPCSTDIECNRYNLCETYTCDLISNICKYSTKFCNGFPCINNECMTGVIYN", "length": 237 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54WA9-1", "protein_name": "Short-chain dehydrogenase/reductase family protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEIKKNIFFITGCSGIGFGGLMVKKLLSRGDYVAATSRNKNKLIQDIGSNENDQFLPIEMNLADESNVKEAIEKCIEKFGRIDILISNAAMGILAPLEETTDKDARTLFDINFFGPLNLIRNSLPYLRNNQFLKNNNDNNNSKLNGPRIIIIDSICGYSSLFNGCSIYCSSKFALHAISETMSIELKPFNIHCCNIAPGYFQTSFLSSCLIPDTRIAEYKDTHSFLDEIVKLNGSRFLGDLSKAVDVIIEISLSYSPPNHVLVGSDAFELFDLKYKKLTNDILINKEICSNTDKN", "length": 295 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54WC3-1", "protein_name": "Cln5-like protein 2", "gene_name": "cln5lb", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNKLIFIIICLGIVDKTISSDFKSYNDGIYSFTYDNICSFKNSIRDQDVYELYYVQAPLLYATYGNLLEKINAYHSGIVLYNKNNGPNITIDYYAIPSFEATLFPKSIIKDSQGNYNITWDTHGLIEVTNYINETYWNKRQLIMYDLSGIQIKQYLSWAPIYNKTHTFYNLFNIESDLSISNSSKIYKNSSTCDDFVWASFDVLYKLGGTIASVQSDPQRDDIKLFISSGEPKIVDYNDSIKRNQIASFFNELKDFANLGKNKTALEIFNELITFFNGYFYCYIDGEYYEMKLSKQNPISFTYLPSPIPIGKRNFNEIKKLGFCK", "length": 325 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54WW7-1", "protein_name": "Probable serine/threonine-protein kinase DDB_G0279405", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MGCIFTKPSPEQQKFDGEDYECENKKNLNLISYIRNLLFGNNSHQQLYNEIIPTTTSTTSTTTNSVYQNIGLDGYNNNNNNNNNNNNNNNIMNNYGYDDYGYSYEEDEDYYDEMPIPTIVAQPQPQPQPQPQPQPQPQQPIRIVSQNQQIPTTPPQQISQFNITGNKSPSSIGSRHRSKPKETLRAHKKRHKDGHKMVNEYVFVRKLGKGTFGKVKLAYHHDTHHLYAIKIFNKIRLKKQTMGIGRPNAFDDVLKEIAIMKKMNHINVVKLYEVINDPQEEYIYIVMEYIEGGSIMSANETSEDLARKYFRDIVFGLEYLHEQKVIHKDLKPENLLVNSEGVVKITDFGVSHIFDDDDVVRCSRGSPAFLAPELCRNESQPISGKGVDVWALGVSLYCLIFARTPFISKTNSLLDIYDQIVNHEPTYPREISNDLMDLFKRLLDKNPLTRIQIAEIKSHKWTTISGTWPMNELDHLILSVTDQEMIDAISTDHTIKPSDNTTTDEDDSDLSSSSGGESSGIIGSSNESKSMYNNVNSKQKIQNQNQNQNQNQNQNQNQNQNQNHNQNQNQNQNQNNNNNSLIEKSNISIPASSSSISNNDSCYENRNVYIKDEEMNMICNDSVIMDPIKELNKIDGLNYGCDFQIGKEYSDFQYNSGHFIYDLVDENESQISRESANDYYLPFKTNKYLNNKSIV", "length": 695 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54WX7-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MARTDNVQLPLENTSIEFEEEIIDSQNDISQQKNYQDFLKNIPTDLNERKEYISSLKKLIKLEKRNHQQIQGEQPNQQEGLNSDRPPPNHHGDHHHSLPPPNHHGDHHHHSQPPPNHHGDHHHHSPPPPHHHGGHHHCPPPHHGGHHHCPPPPPHHHGGHHHHCPPPPHHHGGHHHHCPPPPPPHHHSHHHHCPPPPPPHHHGGHHHHTPPHPPPHHHGGHHHHCPPSPHHHGGHHHHSPPPPPPHHHGGHHHHCPPPPHDGNEYLPQSQTNIEQCICRLNRKKELLIAKIQSIDSIIYNLECLNKQNYQNNYLPSIQLQPTQQPQQPQQTSIKPQQMCQQFFIPQTPNFPQMNNSAPLMYVSQIPVQQSFNNN", "length": 374 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54Y59-1", "protein_name": "Small GTPase", "gene_name": "rsmH", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MFNIFLSKSKDVYRVTSHKKEVKICVLGDANVGKTNFINQFTKSSFNEEYTPTIESRQNKLYKFNRKQFQIQIYDTAGSKELNLFVSDSISQCEGFIIVFSLNDRNSILKIQHYKTLIKNIFKDVEMPIVLVGTKMDLKKEITISKNECKITSVNNNIPNLFYTSAKNKESIIPVFKKLVDLIISKEKKVKKETESNNIKINNQNKIKKQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHVFKTRSNSTLRMKKYLKLF", "length": 272 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54YJ4-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKKVYQDEEFSFFEIGGKKIADLYVRDIITEIRKRGKEITGLGLKSKYELLCILVNRMKEENPSLNIPPKKRVLDFGSLSSTTSNGILQDSNKFFKKDNTHQHQQQQQQQQQQQQQQQQQQQQQQQQHSNNSDDDDDTHNYNDDSDESDDEYIITEEEEIELHKNLNLGDDENLLTLEIKLLESQLENKKFRKSLLLKDKKIKHLENIIQQQQQQLLEQQHQQQQQQQQQQQQQQQQQQRQEEEQQKEQQQKEEQEQEQSSLKNNLKFKDGANLFSIESISNLYNKILNEFNFKKIITEFGDSSLKIHEEFVKFIILKSINLNHNNNKNNNKNNNNNNNNNNNNNNNNNNNNNNNNNNNSSNNLPNGDVNKNNNNNGEIIELVPPPKIDEFWKLMVLDTVGYQQFSNILGAKVNYDTDINPTRKGYQRLKDMKNLYFPPPPSTTELTTDEIWPNHYLLPIQPSPQKQHIQKQQLPSSSSSSSSSSSSSSSSQQHQQHQPQHKQQHQLQQIQEQQPQQQQHQQQQHQQPLQQQIQQQQQQQQQHQPQQQHQPQQQQQQQQPQQQQQQQQQQQQQQQQQQQQQQQQKKQQQQHQQQKNKENNKENNKENNKQNNKENNKLNDNNLNIEVHEDEGNRIINFLISPDTPLRNLFVAYAKEIGENFNSFKFYFGNELLCQNETPSQLLMRNGTKIQAFYLNKKEIKK", "length": 702 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54YV1-1", "protein_name": "Rho GTPase-activating protein gacII", "gene_name": "gacII", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MVRKLFNTSHKKELILDVDTTIVKIGTPKNVVLLTKWLDANGAIKEEGVFRVNGNTTTMEQIKKNFSQGKDDLTKYTSADIHSMAGCLKFILRELPEPIFTWDFYPIFIKIQCLQDESRKLFFLKMLIHGLPYTSRTLVFQLFGFLSKFSVHQDQNKMTPKNLATVFAPNVLRPKKEEDNFQLMNNQDSIGVIETLIEEFQYISNIQKNTLNSQEIKVKSVLPFDETTNAITQQSLVEDYLIAKANTPQESSSFKKNLPFKKGDIIKLLYIKNDGNFIGEINGITGNLSQTYVDIIDISELAEAFTLTPPPIPTLPIASTILHTPPTSSSSSSSSSSSSILLTDNQPKLCSSTPRINNSPSSFSPSLSSTTPQLLVQQSPRQSPRQIPSISLIVEPNNTNQPSFGHGTLQRTSTGYFSSKPLSISQPINMSKPTNMSPPTHHAMSMHNLPPSNTTRENHLPPLPTKPPPLTIPSSSSLPTTPIKQQPQQPIQQPLTPQNHHHHHHHNNLSSSVNTANTGNCANILSPNSDRYLSSRSQSSVHLSGSSSSSSSSSSSSSSSSSSSSSTSNRKFDFSLKSKSSKNSPSKNLPPQPTTTSTLTPPPPPTITTTTTTTTTTTTTTIATTPPPPSKPLPNIPVKDQQFNTLKRSTIEIPPPTITSTNINNNNNTINPRTLNYSFSSFSITYNNSQLGGQLSQEEPPGGVKSQSSYLDNNNLPSRNTNIPNLPPRPPPLNIPQQQQQYKPLPSPPQLQSPQSSLNQSLQIPLQQQQQVQQQKLTTHYILPPQNTNLSGKNLQRSSTSMLLNKLPPPPFSFNKN", "length": 817 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54ZA1-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIKIMTWNCQGCSTIKSMNQTKNTINLIKPDISILTETNLKKDQNLAQIKNHYSTGGKGKEARGKGVMAINHLEQIEIKNLEEKEGRILKFTAILNNMEINIICIYAPASYDRRKGWFSNNISLEDLEQADIVTGDFNINKYAKIKFKDGSSDKRKFTENETIEFLMMEVGLTEILPNSTTKTTFKDKLIDRTFLSTKMHQLNHSYKIIDKINKSDHNIVVMDFKIPNFTKIYKSPLWKMNSIIIKEDKTIKKIEKIIDHYQETKRKNLNITEYWIKFKKKIKKQCITTEKKRILERKKTLSNLANEHTKTKNKYEKETISNEITILQEEERIDRMIKSSINYINNKEIASNLLTSILKKRDSGSQIHRIKNPSNGEIETEQKEITDCFRKYYETLFKEKECDQETHTELLSTWNPPIDKKKLTEMEDRIEEYEVKLAIEKIAEGKSPGEDGITSSFYKIHQHKLIPILTELFNFFLNNEIPTEFKNGILTSIYKGKGDVLEISNRRPITLLNVDYKIYSKIINNRILKILPNIISKYQNGFIPGRLLHNNIIALDLAMEKSDRNTIITFYDFEKAFDSISHKALIRTLNHLKFPRKITNTILSMLTNTNIRVMVNGQLSESFRAGRGTKQGDPISPTLFAIVCECLSTSIRKDNTIIGIKLNQNNSMKIGQYADDTVTLASNIDDADKMDMKVIKFCQATAAKINDNKCVCITKNPKIKTKYKTIGAKEEERYLGFFFNRKGVISKVDDTVNKLENLTKCYSSVSSTLKGRITILKSYLLSQLTFQLYINEINDIKKLENVNANMLFKGDRWAISKERSRRDYEIGGLELWNMATRSNAQKAWIYEQYLREKDDQNCPPHMEVWKSEKENSLSRIHIKCWKAWKLLHHPRERITLKLNQVKPKYENKQKLKVIYRNMMDIKYKGWNKHQPTTGQKLIQKNINHPILPFREARSITTIKGRDLAWRYLLKALPKHHGENCHSCKEEESSMHIFFECKSIKQNIDSIYQKVCKDSNNTYHGPWSEKVLGKLLTPFSSNLIGAIMESIWYRRNQIKFNDNTTIITENQIIHKIKKARDAEWDRTRKIVEKQLRQELRCTDNRESINRTASIKRRLEKFSHNWNSKLMTINIPEHFIPYCSYNTNYS", "length": 1144 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54ZA6-1", "protein_name": "Alpha/beta hydrolase fold-1 domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEKINQTPKKHKIIEPNRKGYSIVGKNTGKPNKIYFETFGNGPKKILFITGFLSSSKGWCKQIDYFTNKKDQYEICVFDNRGIGKSNIDSKYSYNFSTKSMAMDAIDLLEDTLKWDKVHICGLSMGGMASIHLSSIIPEKVQSLVIACVPNGYFLPFFSMGVFNYIRAFFFTFNEKKKARIFQSLMYSDNYLDEKTNGSDETRSEQMFKKNSTGFKDDGPSFLTILGHQIGYITNRFSKKSLEVIKKYSIPTIVINSKKDSLVTIDITKKQIVNPLKPLNFHVIEGGHLSQLENPTFFNKLVENHVDKHSNWDHSTFFQVEKQQFQRQSFMTQNILYSKNYLSSNTLSSSFLNCNTLRSFFNKIKV", "length": 366 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54ZT3-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIAKTQIKCTTIYAPAKSNERHEWYKENLTEEILHSDIITGDFNVDCSVDNNLNKYIKTIFDEFEFTEIKNGITFPRNKSTIDRVFVSKKILHLNPIVTTKEIKLKSDHNMVIIELKIPEYEQQKKGERLWRQNLETLKMNSTSLKINKTIKYYNKKFEENTSKWYKLNICEQWLKLKDEIKKLSINIEIRESNKTKNKLKELAEKLETAKDSRAIFLKEEINNILKEQVRIKQANQTNTHINNKETPSKYLTRRLKVQRKTNEIPQILDPSNNCLVTKNEDILEVARRYYENLYQKRECNEDTHHELLKTFNKRIDQKILDEINQPIEGYEIRLGIEKIQEGKAPGKDGLLPTFYKNHINEILPIISKLYNHFWNTTIPKDFKQGILITIYKNKGDPNNLDNYRPITLLNVDYKIYSKIINNRILKFLNKIISPFQTGFVPRRLLHDNIITLNSTIEIIKREINTKEDMEPIITFYDFEKAFDSISHNAILRTLAHLKLPLKMVLTIMNLLNESETSVYINNSLSKSFTSKRGTKQGDPISPTIFALVVECMATTIINDRCINGVTKETIKILQFADDTATIAYNFMDHFLMNEWIKKFCQATSAKINQTKCSCITFKWNTRTLYTVIKSNERYLGFDFNNKGIKSKINTISDNIRAKLVTWNSTSSTYMGRLIMAKTYALSQLTFHTYINTTPQHNSIENNIVKFVFNTKSKNSLSLQRRQNNYINGGLNLWNLKTRELAQKAWLFERYLHQRVSNTPSSYIKLWEEELKNNNNNKTTTKQNQLQLHWQCKQAWTQLKTPQNKQTHYEHLPKLKKIYEDMMTTQSPEHNKFIPTPGQKEIMTKINSKHLPFKEIKKIINMKGRDLLWRYTLKALPKIYNMPCQQCGEDETSEHIFFNCKAHIKNTQEIFNYTLTKSGHTTHTWNVKILNHLQIALVANLIAIIFDKIWHKRNKLIHDEKEIIIHRQQVIRELIKTQRAAWDRTQAVINKTLRIKSKQRPEEQNKLDSLISLKLLQFSRQWNSPLHAIELPKHLKKYNNSLSTFYK", "length": 1047 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q551H6-1", "protein_name": "t-SNARE coiled-coil homology domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MATRDITSSYILSRTECKNRAKIINSAININIKKSGSGYKRLEEENYQDIDIDNNNNNNNINNNNINNNDNDNDTTNNIKNSNNNNDIQLNILDTEINIEQLNSLPPWILKLNDIDENIKKIISLIEKFKKYLKEDIDKILAEDIEMESRIDCERSIELLTMETIRLFHKTFDMIKYLNKSNNSSQGENKMKKNTQRMKSAKLKALLITFKHIQRSYLALLKKVSSLQRSLSSSFLYRSGEYDVNNDNEDYGENSSISNSHYLQHHHNNNHHHEDDHDHEEDHEEIMDELNEMATTLIERQRVSQLIKETSHLIQDVGSMCVKKDSIFDRIDYNLAEGEELEFNGTILICDGITNGYERPENEKRKKLLLIFAVLIIVILFIFILKYVIEI", "length": 391 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q551V5-1", "protein_name": "EGF-like domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKYLFRFFIFLFCITRINSQTGCFFRETGADYNIDSVFSVFYVDNLFNIFGMTFYMKTCTYVTCDPWRQTMICGNYNSTTFQLGPYQSQKVTLNKNGISIEYLSDKTPPNHPCPTITTTVKFICDKSVLSVPKSDYDYVGTCGVQIKLFAIDYCQTCSKCIASHGSCNSTSGWCTCDSYTMGLNCDQLKASISSVVAPTIDGGSVIISGDFSSIYSLGPSLVITIGSLVCSQVSFAASTTQISCTIGAGQGYQNLTISDGSGSTLQYKQFYYHYPCQEDCTPYGTCNDVIGKCTCNYKYSIGADCKTLNLQLTSVKPTLLDGGQAYLVGDFSNVTGLTLSVKIGIKECTDVNFNETTLQCTIGSGEGIKDIIITSDLLTYSKIGAYEYQYYTCPLGCLHGTCNKYNGLCVCNNGTYGDQCQYIECPLDCSTPNGVCDKDTGICDCDDKYSGEGCDFIKCPLDCSTPNGVCDGKTGICNCDEKHSGDSCQFLQCPLNCSNPNGICNRNTGICSCDSKYSGEGCDFIKCPTDCSTPNGTCDGKTGTCKCNNPYTGENCDEIAKCKQECSLKHGTCDSHTLDCICDTQTKGLSCEESRLLIESADPTSLDGGTTTITGYFGTTTSLLSIKIGDSQCTNIKVESDTKLKCDIGPGEGTHNVTVTDDDLSFTGVGMFQYVGQINKISKISGGAIAGIAAGCVVGVSVLGAGGYYQYRKNKKIELFMS", "length": 722 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q554Y8-1", "protein_name": "ADP-ribosylation factor-related", "gene_name": "arrB", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MGMGFSFIEKKDFKRFLILGIDNSGKKKIMYRLKFNKDIPTRPEKGFFVETFERRFKYNNEDVCGQNMIRPLWPNYYTDETNGLIFVVDSSDQERIEEVRLEIKKLDENIKIFKNHPFLIFANKQDLKNSLSIEQLIDKLELNKLSLNRKWHIQSSNAITGDGLEFGLNWLFSSSHNFT", "length": 179 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q555E8-1", "protein_name": "Putative fatty acid elongase DDB_G0274669", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "METVQSIITEWTDPKSWEKLVQHSFKDSNWKELIDPVNYKFNFGVTPFSQFQIIPIVLVIYLVTIFSIKFLMKNRKPFSLKFISILHNAILCIWSLIMCVGVLYEIIKRVSNEGPLFTVCEDPNGGFDKGVTYYWSYIFYISKFYELLDTVIIVLKKKPLIFLHVYHHCKTVWWKKYITMIQILQFVCLGIAGVLHVYTINTIGCFTHYPAFAAAYSINFSFLFLFSKFFVKSYTPKNSNSNTNIKSKKID", "length": 251 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q555Q5-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MRSIRIKKINFHIKQGEEQLKQELNNYCEETSLKYISARIKKRHNDFTINAVKDAQGRTINKQELIEEEYVKYYSNLYDYKEDDAPSHYEMLENWTVTRDSTWDNLENEFTTQEILEVIKQLNPHKSPGPDGIPNLFYITHKEKLAPILASAFNDTLRNPHLISKNYKEGLIITIPKKGDPELIKNRRPITLANCIYKIHSKLINNRIIPILTKVINHNQKGFVPGRFIIDNIISMNELINYCNDKRINGIITLYDFEKAFDSISHGSILRSLQHINIPTNIINLIMNLLTKSEARIEINGRTTIPFEIKRGVKQGDPLSPTLFVLVIEALARKILQDDRITGLPLNNSDHREKFQSFADDSASMVPDSQQLELVLQHFNSFCKATSSKLNIDKSSSILIGNPDNTNQRIPISTNPERYLGYFFTGKGITRKIPEILNTIRSSLVLWKTTDSTIKTKTNILKAFALSKLTYYSYVENFKEEELNQINKLVEWFLSAPNTKMLVDFKITPKLSPTAKKDQEVNADYANHRFHKEYFEWNYKAIDYDLTRSFAYRNLMALILHNIWIWICNQIYSEDPLTDESLSYSSLLKKWHKLATLEYIKKAKDLKNLSAKDHNNFKDPKILLTSTIKLRKTTANYYCIPESSLPNIISFDQFI", "length": 655 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q556H5-1", "protein_name": "Cofilin-3", "gene_name": "cofD-2", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MTTPKPTIAKISPECQTHFQDIKFRNKYQGILLKVNEESNMVVDKTLVAEGEFSELAQSLPTDQCRIIIYRYKSGEGSKLFFIYWGPDSAPQQDKLIYGNAKVTLAITLKGIDHKISASNLKEISEQVFIDRITPKTA", "length": 138 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q556J5-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MWNHNLCHAINLDRQFDHINNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNKNNNNNSYDYSFSVHSSQQYSRHYPNSCNNEQTKPKDYYDHASRSQHDYHANGSNNGNNNNNNNNNNNNNNNNNNNSNNNNNNNNNNNNNNCDSNYNSNNNNSNNISIANIKYQQDQHYQHSDTYTSHQYNSFNDNNNNNNNNNNNNNNNNNINNDNDNNGYNQYDESEEDEEEQDDYDEFDIQDSASSYNDNCGVLNSNTYIYDYQSPQQPLYSNEYQNNNHQPQQTDSYNYNNTNNDNNSYNINNNNNNNSYNNNNNYNNSNNNNNIGNIDSNTNNNNYNYNYSNNGDVYNGYNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNMNNMNNMNNNIITSNREQFYSNNNHNNINQYQYQSQQQQTQQQQQQTQQQQQQTQQQQQTQQQQTQQQQQYLTQYYQQELYSQSYKCRPYYQNSFVISKC", "length": 480 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q556P1-1", "protein_name": "CWH43-like N-terminal domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MISSSLKPSVLLWILAILIPSTLITTYTLTVLLFHGIRRTVPYISDTIDFSPESCIGTFFISISAFLVFIVVFVKHFLLQNNINQNFNIDIILNENENEKKKNRAKMLNRISTFLGLICGVCIHGVSSFQYHNTGLVHSIFAASFFFTGFIYIFTQTYLDHKFSKLPKRILILRRVISLTTSVFIGYIILQFFIDNLAPILKIISALSIFFYLISFFYEFSKITINFQINTISQIEHQKEYNENSALLISQ", "length": 251 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q556R5-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MFNFERIDHGSGKGTGIAIENRDTRKGHISINFKDDDGRILSIKYNSFNSINILLINAPATISERNTFIINSKSLFKKYNSINHQIIAGDFNNNHDCNSFFGTELRKIIDQDMLLDTGIEENTPTFPRSMKRLDRIYCHPTLLNQNSKLVVHNTVFNKSDHFPITITIQTNRETTTTTTTTKLERLPWTLCKEILNNKHIHDGLSELISKNKDKIKSVEEWTKFKNNVIRDYLKKEQNKIKKEKNKRKYVIHKLLGNSDIIPKMRKELNEEISRILEEERKVKAWDIKLKLHLHQETPSKYLTSILKSRAKDKSIFQIKDKDNKTISDKENIAKRFVEFYQDQYEEKEDNEETHKKLLEKWEVDVDLIKKLEIDRPIRIHEVTKAIKTSSIHKSPGLDGINALFYKYHINSIARILTIAFNDLLTNKKEIPTKFKEGVITTIFKKGDELNISNRRPITLLNTDYKILSKILNSRLLDITSKIINKFQNGFVPNRFIQDNIQIMKEVIEISNKRKNNTLITFYDFNKAFDSISHKSITRTLEHIGIPPKFTAILLNLLKDTKNKIKINDFLVNGITIRTGTKQGDPISPTIFALVLEPLLIDIINDNTIKGFTLPNSKSLKLTAFADDIATFTNSTEELMKINTKIQKYCSATSSSLNKEKTVMIAIGDKPHDLPFQESTVPERYLGLNFTKTGLNSKYNTLIQEMKNNLIKWKSQAITMKAKMTILKTYVLSKLTYHQYMDNLNEEQIEEINNMTRWFLFSSVKNTYTEERKYKTMMKIDRAYADWKEGGIKLWDIELRHIAFKIWYMNRLLHNNYNNNNNTLQEWYMEQLSRKKPTLQPSTICADTGVYSESNFTKTIQR", "length": 861 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q556X2-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIAKTQIKCTTIYAPAKSNERHEWYKENLTEEILHSDIITGDFNVDCSVDNNLNKYIKTIFDEFEFTEIKNGITFPRNKSTIDRVFVSKKILHLNPIVTTKEIKLKSDHNMVIIELKIPEYEQQKKGERLWRQNLETLKMNSTSLKINKTIKYYNKKFEENTSKWYKLNICEQWLKLKDEIKKLSINIEIRESNKTKNKLKELAEKLETAKDSRAIFLKEEINNILKEQVRIKQANQTNTHINNKETPSKYLTRRLKVQRKTNEIPQILDPSNNCLVTKHEDILEVARRYYENLYQKRECNEDTHHELLKTFNKRIDQKILDEINQPIEGYEIRLGIEKIQEGKAPGKDGLLPTFYKNHINEILPIISKLYNHFWNTTIPKDFKQGILITIYKNKGDPNNLDNYRPITLLNVDYKIYSKIINNRILKFLNKIISPFQTGFVPRRLLHDNIITLNSTIEIIKREINTKEDMEPIITFYDFEKAFDSISHNAILRTLAHLKLPLKMVLTIMNLLNESETSVYINNSLSKSFTSKRGTKQGDPISPTIFALVVECMATTIINDRCINGVTKETIKILQFADDTATIAYNFMDHFLMNEWIKKFCQATSAKINQTKCSCITFKWNTRTLYTVIKSNERYLGFDFNNKGIKSKINTISDNIRAKLVTWNSTSSTYMGRLIMAKTYALSQLTFHTYINTTPQHNSIENNIVKFVFNTKSKNSLSLQRRQNNYINGGLNLWNLKTRELAQKAWLFERYLHQRVSNTPSSYIKLWEEELKNNNNNKTTTKQNQLQLHWQCKQAWTQLKTPQNKQTHYEHLPKLKKIYEDMMTTQSPEHNKFIPTPGQKEIMTKINSKHLPFKEIKKIINMKGRDLLWRYTLKALPKIYNMPCQQCGEDETSEHIFFNCKAHIKNTQEIFNYTLTKCGHTTHTWNVKILNHLQIALVANLIAIIFDKIWHKRNKLIHDEKEIIIHRQQVIRELIKTQRAAWDRTQAVINKTLRIKSKQRPEEQNKLDSLISLKLLQFSRQWNSPLHAIELPKHLKKYNNSLSTFYK", "length": 1047 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q557C9-1", "protein_name": "Homeobox protein 5", "gene_name": "hbx5-2", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "METIVNNQNNGQQNTVPTQSFSSSVYMNYDFFDSQQLQQPQHQPQHYQQQDSFVSPNLDNNNPQIHVQSNNYNQNGFVGYNNSNNNNNNNQHMNNQYSNSFHNNNSSGFMAFQNNSSNFNNQNNNNSNNNNNNNNINSYDYNNSNNNNYNNNNNTHSNNSNNNNNNNNSNYWNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSNNNNNNNNNNNHHHHHHQQQSQPTSPYNNPIQHNPNDMKFNGQHNPFNGNQMVMDNNNNNNNNNNSNVFNSNSNSNVFNSNSGSFLQINNNNGSFSSYNNNNNNNNNNNSNSNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSNNNNNNQFSQSYDSTLGNNRFSSMMGQPIQQQQSPPQQQQQQSFIQSSPQAIPASNCNGNGSTSSSTSPLSPTLIGSAPGTPTSMLATTLFGFNLSSSPTSSPSSPVKKGKSQSALALSSSGGSGGSSGRKKPQKHDSMSSITNTNLKSTQASTLKESKRSNSSPNLKKQMQLQQLQQQQKLNENGTLIPPLPFASISENITNNNNNNNNNNNNNNNNNNNNNITNNPLSGSMEFPNSNNINQSSDSINGEFNIGQPESPKMYNSSPSPPPNATSTTKGGKKSKKSLHISTTQQSPSLNGSTGGSMLTPTMSGLSLSGGGSGGGFSPLISPTGTTSNKDLQSSPSPSPLLKSMSMGKLDLQDSIDSMSSPLSPNSSLSSSNGLLPPPPNSNNMNSSGGIPTPSTPTSPPPLTHHINIFSNLEFVKQLKDHLLPNDFKPEEHALERNLLRFQQFVKTLAEPLQRDVVTSMFELSVDAQLQYGSNLDNDNLSALMLFRRKILNFNLFRMMMLNDPNSFIPLPSPFPIQTTTISSNGTIVNPTNVNNNNINNNNNNNNNNNNNNNNNNNNNNNNNNNNTTTTTTTTTSANTVQSGTTSNSNLVFQQTSNSNTLSPSQQQQQQTQQQQSINGSSTGSLSDAQYQDLGIHLDTSSANSGCGINVSIGSSIGGGGGGSSLNGSNLNGSSSISGSISGGSSNGGGQFIMSPQFSLDGAYQQQQPSSYNINNEMELAEKDEDEIFNNNNKDNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSSSINSNINNVNNCNINNNSNSNNGSINSPRPSTPTTLNSSGKRSKKIYRGDSFGAGNDISTGLMASSDQIIPPPQQQQHQQLVNNNNNNMNNSENNILLADSNKGLSVSLGSLPTNTPSSMEIEQQQQQQQQQQQQQQQQHLNQQQILHQQLHHHLSSSLGGAQFTNIQQQQQQQSGNIFYNSPYNSSQVYMNPYGTSITNTSLAGPSTTSSAMQHMITNMTSSNIIVNNQNNNNNDQNNNNNNNNNNNSTTNSNVNNNNNTTNTPSSPPQPNNCTPTQTSIITSNGVVVPSLQMRGTITNPPPVLPTPDTLVLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQETPHTPTSNSISSPRSSPVHQQSPSNTNTTTTSTTTIRHSAVTQLSFAGLHNQQVSPISPRSPRSPHGTSGDYNDGSQSPSSRRKNRFTDFQIKRMNDCFENLDKNNNGKFTSEEICQIATELGLTDQQVRVFFQNKRARSRPSPRGQPTNPLTSSTNNGNNSNLALQHLQQQHLQQVQQQQQQLLQLQQQQQQQQQQLHQQSANTTPQLNSMNPNSINYNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNIINNNITTINE", "length": 1723 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q557D0-1", "protein_name": "RING-type domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MTGSNNLNSLNNNNNNKISLQETIQDIIKCSICLNSPKNPRFCPRCSALFCLECIDRWIISNPTCPACRDTLTSDNLNSNLIVSNILNELVKSEQEEYTSSDICNYHGYERLYYCSTCQEPICSDCALFKHKDHKIEKLSINFNKNLEILKIEEEALKKRQEELIELNSFLELDAETLLKNKSQIEKEISKVVITMKARLKYDFERRYNTILESQEKINNELTHLDFIYNDLLNHYKKSPSSFVLTSQQFIGVLQSVHKNSIMDIYTPINTDLTSELIPPFENRLLKFENFTTGDCLFSSRIAFYGMTWEIKCGIEEDNCFLNLKVLECNSDGKYFYMFTIVNQKTNVNKLIEFDLPFQAGETFYIPNFSSKQTLIDEGFILPENDILLLQFSFRPQNYFCYSNDLKRYIDILEYRHRGYFGEEDEDDGTIETTVTKLPNDKSTILGSDNYNDNYNDDGIGDLDEDEEEEEDDEDDDDNLDDHLQYDNDDDEDEEEDDEEQNEEDNDEEGTNIPTSEYEDLDTSSASVISNINRRDRFKNNNINNNNQFVNSNNNNNKYNTTNSNNSIVGSSRYINNNNNNNNNNNNNNNNNNNNNNNNNNNNNYILNRSYSTNKIYNFYQDEEEEEEDDDSNIDDQDEDEEEEDSEEESSLSSSDLQDLDSSGDQSSLEFSFSKYTNNYYSNNNNNYNSGGGGGVGGAGDNNKIECIRRDFNNLLKRINFTNSQLTNLKPGVPKDGDLLNDDENDKKCNIPLNEDEEEDEDEEDDVNKNKTTSTTTTTTTATTTNEVVTINPNTISNNSQDEEEVKSDIVKLLENGIANMLNNSNSSNRSSNNLKQQQQQQQQLQKDDQKQKDEQQNKSNTGCDIDQLNILSKLSIKESCDSIKNNDNDSLGNSTNNNNNNNLNNNNNNNNNNNNNNNNNNNNNNSNNNNLQSFLQSNENTENETDFNDNNTNPETNTETENEYLTSSNMNLDGGESEFDSNKSYEGSSTDENFNSDEDYQDEDNFNQDATGSESANNDDYLDDNEREGSDSIENYDEDIEKVLTSHNIITTPSIPPSQQPQPQLQTQPQTQPQSQPQSQPQLQPQSQPQPQTQPQLQPQLQPQLQPQLQPQLQPQLQPQLQPQTQPQQQKKYDDLSENQIQTENRNKKIKEEINNKTNNDNNNELGKSSKSNTSSSSSSSSSSSSSYSESESSESDSNNEYDNEDEDDIVNQVSNFNFNFNDASNFKNFSFRPKFPSDENDNDDNDDDYEINIDLKNIQKISPILRAIENGESNINHYQSPVSLSSSSSVSSFSGSGNSVPITATTTTTTTTTTTTTTTTDDDSGINMPISPLSASPPSPPPQNEPQINNETNDNDVKLPQI", "length": 1364 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q559A9-1", "protein_name": "Probable polyketide synthase 13", "gene_name": "pks13", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MENFKYRNNENDVAIIGIGFRLPGCKNFTPNELWNNLKNGFNGVVELSNRWSDNFYTMGKVSSAYAGLLPFDELKSFDPLFFGINPTEVPTIDPQQRILLKCTWEAFEDAGIDPIKIRGSNTSVFIGTSTNDYQRIIREKDQTITNAFGTSLHATSNRISYCFDFRGPSMTLDTACSSSLNCVKLGYQSIRDGTSNLSIAGGVNLIIDPYFTASISDLNILSKTGSCKTFDASADGFARAEGSGIIVMKNLKQAMIDGDKIYCVIKGASSNVDGGGLQDKSNFYAPSSLSQCNNIKMALKSTNGTVEPKDISYFECHGTGTPTGDPIETRGISMVFNDESRSKENPLLIGSIKSNIGHLEAGSGIASLIKCCLMFKNKCFAPNINFKVPNPKIKFEEWNLKVVTEPIQFTKSNTCIGLSNFGVTGSNCCLILSQFNNNNNDNQIVGNNNNIKSNKEYLIPFSSNSVKSLENYQQLLIKNGENEFKFLEFIKHQIFTKPTSLYQRSVVIASSWDQFNNAKIMKTSNSKSSNISIERNNPITVFVFCGQGSQYDRMGLELYNNDFIFKESMDLLDNKLSKYYGYSVLEKLRNCDSKSIQHPMIAQPVMCMFNISLFELYKHWGIEVSFIIGHSLGEIPAAYCSGMINIDTLCYLIYHRSIAQTKTHTNGRMLSINISADEYFSQYSKQYPDIEIACFNSPTSIVIAGNEQKLNEISEILKEKGIFSAMLASLSSFHTSSQNKVKEDIVNKQFDSKQSEIPIFSTVTTNLFDSVTSPFNSSYVFNNIVSPVKFSQTISNLYKHIESNQLGNDIVFIELAPHPTLQFYLKQMIPKPTNDDNSIEFKVSVYSALNKKNNDIEEIQRTISQLYCDNGYNVNFKCQFQHDDTHGSINSNINQLSNISLPHYQWDDEKYWKEDPSISKLIVNGPQTDNLGYLNENSPNSKSYETFIDIKRPPFQYLKGHMVKGKYYFPGCGYIDNLLKIYKSQDLTINQMGFKSPLIFIEGVNQALQTNIFKKSTSNTTTNNNDEFRVEYHFNDQKTNRWILSSFGDFQLSNHSSNSDNLEKINIKQLIQNQCNLTKLSRDELYSHIKSKTGLTYNGVFQGVNKCYLGENCSLSEVSLELKREPSSFFNTAVLDTCLHGMLCLLEEQSQLVFDRIEGFKYHSSNVPTSEEEMKIHSNIYVYSTINPSRIGDSYSASIVIMMEDGTVLIEIENAVCTSLTPIKESISVKYPTNQLFSMYLQSKDSPIPSPLNFKSLYNQNQQQLKIDKQFTDWMQKCEKFISNQFFKNIEKRNPEINLEILNSKTIIELKSKYCQNLKNERLFQFVFETIKQLGVNAYDDDDDLTIDSSEDRKSIYEILIKSTKVIPKLLFPLEDEDLTIDSPQSLFENGLLDRFYNNPNLMTNQCQLIAQIIKESLKPLLNKKMVFRILEMGGGTCSLSVVVLNLINQLLLENPSFEIDIEYTWSDISPSFISAAKEKLSHIDKRINILYRSIDIEQPFIEKQDLSPSYYDFVIMSNVLHVVKKLSPSLDEIHKILTPNGHLLFVEIPYKELISDSIFGAFNQWWAFEDTDIRKDRCSIPPNQWIQVLSNHNYKDTIVSDNKECTWCCFVIHSQKPSLLELSKKIECNQYDNIIVFGNENSQDNFTKSIKLSYNNNIIKWVSNIVEIKKFIKLNIITNNSIIYFTKGIEELTIDNFKLINFQYIQINQLLLKYESKCKNVLVTRDCDGSNYLASSLIGAARYFDEYRQLELFTLDFDNDTIQSCDECSSSSCSNLIKLIEPLIDPKINIQREFLIRNNRVYFERAKLETNLKKSFKSESFENSNKLISTLNFNLDYQLQSKPFKQLLQNEIEVEIKATGINYRDYLVFTGSLPIEKTNHNGISNQPEFGVDFSGIVTKVGGGGGNGEFKVGDRVYGIGHNTTSSHITIDSRYASLIPNSLDYIEASSITSSYILSLYGIFDIGNLDIQDNESILIHSGTGGIGLSALNSLRWKGHKSHLFVTVSSKEKEQYLRDNYGSFITGIYSNKDKNYPKLIKEKLNQLGSNKQGVDLILSSLPNGDDNLNFKCLAKNGRIIDLSNNIDLFNISKSKIKKLLNTINDGFESGELQVIPIIEFSNSNIRDAIEFINERQHIGKIVISHDDSNLLIDLINKHSNQPNYSILKSDYQISQSNLGKNILITGQSGIVLEILKWIIKFSNSIENVIILSKSLMKWELELLIGKTMKKANNKIKFHFKSVDVSDSIQVENSINQILNDNPNIVNIDSIFHFAFTQITKKVEEIDMESLNVSHNAKTIGAINLHNQSINRNWRLNNFVMASSATSIIGSTDQCSYVCANTVLDSLSKYRKSIGLPSICTNYGAIESAGFVSKNESVAAMFNGIGIISISTDLILGTLDLQIQNQQSSTNLMLSDFNFLNFVNNNLQLSLISKFDFQTNLAKNQVNEKLQNQTQNQNLQIQSPSSTTDCQTIIKDSFLHKISEVLSIDISKLNLDLKLLDYGADSLAIVQIKNWIDMEVSPNLIVIQQLQTFTITSSIQYTINSFLKKKVQSQE", "length": 2551 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q559I8-1", "protein_name": "Uncharacterized protein DDB_G0272530", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKIKLILVLIVFLTIVNVNNSIDLCLSNPKKALVNQACKYSTDCEYPLFCGSGNGYGKNATCSKNIETGGSCESNNQCTPCNVCFNAKCKVKLYLGDACDENKSYCSSSVCIKGKCSIQGDVCTANNQCKFNNYCKSGKCVPLEKEGSSCDKDSSCSLTNACVGGKCVTKYQKPLGAVCNSSNECQVFSGHVCGANGKCSVYNQLLSKCKENSDCGPNGMCMCKSETENVCVDLSVGALKNDKCPSLLSSFSSCMTRERCTENTPTGCPKCYPIFMCYQYSCFYMNQFIRSTQNYYKSFCS", "length": 301 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q559Z2-1", "protein_name": "E2F/DP family winged-helix DNA-binding domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNISLLLNNRNRNRNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSNNGNANESASLNNGSEEIRSNPSSNFSSPIQSSLSSSSSSLSSNQATTPKKRSHAHKNSLKCQSPQMSPQMSPQMSPQMSPPLQYFPQHQMQHLSQYQLDHLQQQQQLIQQEQQEKQQQQQQHQHQQQQQEQQKQQQKQQQRLSPQPRSSQPRSSPPRSSPQRSPQLNQQEGHINSVQTYSGNNINDKNQNNTNNNNNNMSNNNNFHDDNNCNVNYNNIRNNSNNNNNNNTNNNNNNNNNNNNNNNNNNNNINNNNNNNNNSNNNNWNNNYCNNSFADETNKNNTYGMEYINISEENQYNNNNNNNNSNNNNNYNNYNNYNNNNNNNNNNNNSNNSNSNNNNNNNNNNNNNNNNNRNNIINSNINNSNNNNYNDNGYNNNSNINSNDSYNNNNNNNNNFNNNNFNNNNNNNNNNNNNNNNNNNNNKNNNNSNSYNNNNNNYNNNNNNFHNNNNNSAHNNNNNNYNNNNNNNYYNSNNNNNFHNNNNNNNNNGNNFNNNNNNNGNNGNMFTNVNSIDNVNRNNYNNYNGNNNYNGNNSNNNNNSNNEVSQITTTSLPVKKTKVFKAPREKKFKRGPDQDIREIKPATALLKQYFIGNSITEFNAERVGSILKINHEKLKDILDIMECASLVINNHSNNYVWLGLDNPGFLKLVFNVFHCSSNLVTKEPEFACLKCKENAYRCPTSVDLPKDTRLGSTVCQFMKLLLSKRIRTNPVNDFLTIYQVCFNFNFCSEGRCPEEDFKYLRNTAKVKRCYDVANVFNGLNILEKVGKSKIHSYQWCGDFTIQDCENGCPFGHPLLTPGTAYTTNPSPNPFNQFSNAYISSSAQSSLSNSPFIQGGFHGNNNNSNNNNINGNNINGNNNYGYNNNNNYNNYNSNNSNGFNNGNSFFQQQQPLVNSGVSMVRNNNYSYSP", "length": 964 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55A39-1", "protein_name": "Transcription initiation factor TFIID subunit", "gene_name": "taf9", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSSNETLPNSEQENNSKTDTKNDNKNIGDENKIIDTDKDMKDNDTINGKENGNININSNNNNNNNIDTDKEMKETSSIEEDDNNNNKNQNNNNNNNIKEENDNLTELKNNNNKENKENKEETIKEDKEKENNKEPVKNKEETNNINNNNNKNNNSDNINNNNNNNSKETLNKISSMSKVSLTSESSEINGQVNTGVVNNNTNIDITQTNLDEPRDSRVIKSILKTMGIQAHEPRVVNQLLEFMYKYVFEVLQDAMIYGEHSGKTDIDVSDVRLSIQSRVNYQISTPPPRELLLSIAEEKNKTPLPPIPNRYGVFLPPDEYCLTNPNYQANPTKPVFQPVQPLVGNTSRGNYNKKQSDKQVSIKFNSMSNNSTTTTTTTPPTIGSQNGTTIVSPPNLGSLGTTTTTTTTTITPPPPILPLSSNIKPPTLSIPSSITSPPTVTTKNTSTPIIGLGSTTVAPPKTSSSSSTIAPPVLSLPTSITSPPTVTASSTTTTTTAPTTTSPTIPSLSSPTTAATTITVKKEDVKMDDFDDFDGQMKDDITPSSTPQQPSQPTESETTTTATATTTPAVTTTTIPPTTTSTTPPTTATTSTTPPPSTTTTSTPPTTSTTPPPQIKEEK", "length": 619 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55B17-1", "protein_name": "Amine oxidase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MYKKILLIFALFILVNINFASSEFKKNETESANLKSLYASYLMKNNNNTKYNNNDNSNNTNIYNDSVTKNKSKNKNELTVGIIGGGIAGLYAGMLFIKSMIFDDLGIDYTILEANKERVGGRVYTHKFDDHKYSYTDLGAMRIPLTPLMDRIVSNQNYSLFSKLAKGGYQIPTVPFLISVNNEISYYNGIRVLKGSPVLNPSDPFNYSDSNNGGPGKGIPDEYANRTVDSLILPVFYQFINNLTVDFYNGFKQMLKYDSYSARDYLKTFHNYPNSVIEYIENLSTISGRLDQTSITELLMSVFDFSGEKFVCVEGGTGLIVKSMSQIIKKKVEMGSFVTKISKSFDKKNNEIDGLNVEVVRDSNFGGSDTEILKFKHVISTTTLPALQRIDTSDLKLPLKLKVAIRSLKYTGAIKLAINFKYRWWEDSEFMSGKPIRGGSSNTDLLLRQVVYPSYGINNGTKGVSGVLLASYSGGLESIRISSMIGKKDKERKLLNIVLRDLAEIHNVDLKKLKNLYKDHFFQSWDNDEFSSGAFALFSTSQYTELFPSTGQSHVDGRFHLSGELTSVHHAWMIGGLNSAYRSVDLILKNEGFEDLRIKLRNNWGTIEQAEYPSLDWYKYDSDINHYKLY", "length": 630 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55BT6-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKLLYIVVFLLFAIKLCCSEYCGETYCVENRNCYSFIGCRNSTCLYETIDLDDEVDCTVDTCSDRYGVKNTPNNSLCPPENLCDMFLCDTQSGCVAIPKVNCPAPNPCQIPLGCNRETGICEYDEIDCHDDNECTNDYCDPILGECVHFSNDTICSNKASNFSTCVLSGVCGEFGCKYVEDNCNDGNPCTDDYCDFKNGCVSQKNDWNCDSLSACSEGICTDNGCVQQEVDCDDDNPCSEDFCHPLFGCGSILNDTICTNGNKCVNSTCTEDGCSLPVPIVCQDGNPCSDDTCNPSTGCQFTLNNSNCNDGKKCTIDQCGLNGCTHTNITCPPKRVVDIILIGLICRNHYCDQSTGNCVPDMNSVSLLCI", "length": 370 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55C69-1", "protein_name": "Chromo domain-containing protein", "gene_name": "hcpC", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MGKTNKKKIEEESEEEEAGDVFEVEKILDKRVQHGRIQYNIRWKGFSADYDTWEDEANVVGCPELVREFESSRIKEKKKNRKRKNVIIDEDPTEEISSSLSSILSSPQPQPPPPLQLTNHSPASSELAITTNTFLISNCTSTSNKTKISIENEEIIKNDHARYGVPYVEGIGFENGDCVDEIVGCKPFGENNLLYFFIRWRGKEKLSWVSNESIKQKEPLQLIEFYESRLKFGYKGEEN", "length": 239 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55CH5-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIAKTQIKCTTIYAPAKSNERHEWYKENLTEEILHSDIITGDFNVDCSVDNNLNKYIKTIFDEFEFTEIKNGITFPRNKSTIDRVFVSKKILHLNPIVTTKEIKLKSDHNMVIIELKIPEYEQQKKGERLWRQNLETLKMNSTSLKINKTIKYYNKKFEENTSKWYKLNICEQWLKLKDEIKKLSINIEIRESNKTKNKLKELAEKLETAKDSRAIFLKEEINNILKEQVRIKQANQTNTHINNKETPSKYLTRRLKVQRKTNEIPQILDPSNNCLVTKHEDILEVARRYYENLYQKRECNEDTHHELLKTFNKRIDQKILDEINQPIEGYEIRLGIEKIQEGKAPGKDGLLPTFYKNHINEILPIISKLYNHFWNTTIPKDFKQGILITIYKNKGDPNNLDNYRPITLLNVDYKIYSKIINNRILKFLNKIISPFQTGFVPRRLLHDNIITLNSTIEIIKREINTKEDMEPIITFYDFEKAFDSISHNAILRTLAHLKLPLKMVLTIMNLLNESETSVYINNSLSKSFTSKRGTKQGDPISPTIFALVVECMATTIINDRCINGVTKETIKILQFADDTATIAYNFMDHFLMNEWIKKFCQATSAKINQTKCSCITFKWNTRTLYTVIKSNERYLGFDFNNKGIKSKINTISDNIRAKLVTWNSTSSTYMGRLIMAKTYALSQLTFHTYINTTPQHNSIENNIVKFVFNTKSKNSLSLQRRQNNYINGGLNLWNLKTRELAQKAWLFERYLHQRVSNTPSSYIKLWEEELKNNNNNKTTTKQNQLQLHWQCKQAWTQLKTPQNKQTHYEHLPKLKKIYEDMMTTQSPEHNKFIPTPGQKEIMTKINSKHLPFKEIKKIINMKGRDLLWRYTLKALPKIYNMPCQQCGEDETSEHIFFNCKAHIKNTQEIFNYTLTKCGHTTHTWNVKILNHLQIALVANLIAIIFDKIWHKRNKLIHDEKEIIIHRQQVIRELIKTQRAAWDRTQAVINKTLRIKSKQRPEEQNKLDSLISLKLLQFSRQWNSPLHAIELPKHLKKNNNSLSTFYK", "length": 1047 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55CH7-1", "protein_name": "SsDNA-binding transcriptional regulator", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIFKITRTKRRWTKNQKKILVMKVVEKKVVVKKSKTPNTSPSSSSSSSSSSSSSSSSSSTNDKSFNLSDKRKISYSNFKGLERIDIREFFEDKSGELKPSSKGISLTREQLVVILENGDTIKDWIKESK", "length": 129 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55CJ7-1", "protein_name": "diaminopimelate epimerase", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEPSIDNKPSFRINFTKMHGAGNDFVVFEKNKVERLNGDKSTVTFEEIVGFTTKIAHRKLGIGFDQLIVIDDNPIDKNAAYGMDVINCDGNIEVMCGNGVRCFSKYIVDNKVLSKNLKEQLNFDGDDDIEQIIETKSGIVKTYPLLKHHLNNKDNDVIMVKVNMGTPKVSRFINEIDRHIPKVLTNQSPIESYMYTIDIGLPYCSKLECVYVTVGGNQCVVFIDRNIELGYLDSSYGDHTKFSTIDFKEISDIIQSNVNGFDDIPNVEFVIQSPQDKLENKVISRVVERGNGETLACGTGACGVAISSILKGYCNENTEITVEMPGGKLLIQWNPNNEIFKTGPATSVFKSQILI", "length": 355 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55CV8-1", "protein_name": "Lipocalin/cytosolic fatty-acid binding domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MELLVGGTILGALTYAYSSLKRTIPEGAHACSPFYPEKYVGKWYEIARLDFYYERDMNNVSAEYTLNKDGTISVINSGYNYVEKKRESVNGKALFVHGSDEAMLKVSFFGPFYAGYNVIAIDPDYKYALVAGRSLDYLWILSRETSIPDHIKKQYLELAESIGYNTSKLIWTEHDNINNKKD", "length": 182 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55D49-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIKIMTWNCQGCSTIKSMNQTKNTINLIKPDISILTETNLKKDQNLAQIKNHYSTGGKGKEARGKGVMAINHLEQIEIKNLEEKEGRILKFTAILNNMEINIICIYAPASYDRRKGWFSNNISLEDLEQADIVTGDFNINKYAKIKFKDGSSDKRKFTENETIEFLMMEVGLTEILPNSTTKTTFKDKLIDRTFLSTKMHQLNHSYKIIDKINKSDHNIVVMDFKIPNFTKIYKSPLWKMNSIIIKEDKTIKKIEKIIDHYQETKRKNINITEYWIKFKKKIKKQCITTEKKRILERKKTLSNLANEHTKTKNKYEKETISNEITILQEEERIDRMIKSSINYINNKEIASNLLTSILKKRDSSSQIHRIKNPSNGEIETEQKEITDCFRKYYETLFKEKECDQETHTELLSTWNPPIDKKKLTEMEDRIEEYEVKLAIEKIAEGKSPGEDGITSSFYKIHQHKLIPILTELFNFFLNNEIPTEFKNGILTSIYKGKGDVLEISNRRPITLLNVDYKIYSKIINNRILKILPNIISKYQNGFIPGRLLHNNIIALDLAMEKSDRNTIITFYDFEKAFDSISHKALIRTLNHLKFPRKITNTILSMLTNTNIRVMVNGQLSESFRAGRGTKQGDPISPTLFAIVCECLSTSIRKDNTIIGIKLNQNNSMKIGQYADDTVTLASNIDDADKMDMKVIKFCQATAAKINDNKCVCITKNPKIKTKYKTIGAKEEERYLGFFFNRKGVISKVDDTVNKLENLTKCYSSVSSTLKGRITILKSYLLSQLTFQLYINEINDIKKLENVNANMLFKGDRWAISKERSRRDYEIGGLELWNMATRSNAQKAWIYEQYLREKDDQNCPPHMEVWKSEKENSLSRIHIKCWKAWKLLHHPRERITLKLNQVKPKYENKQKLKVIYRNMMDIKYKGWNKHQPTTGQKLIQKNINHPILPFREARSITTIKGRDLAWRYLLKALPKHHGENCHSCKEEESSMHIFFECKSIKQNIDSIYQKVCKDSNNTYHGPWSEKVLGKLLTPFSSNLIGAIMESIWYRRNQIKFNDNTTIITENQIIHKIKKARDAEWDRTRKIVEKQLRQELRCTDNRESINRTASIKRRLEKFSHNWNSKLMTINIPEHFIPYCSYNTNYS", "length": 1144 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55D57-1", "protein_name": "J domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIQVKNKIKIISILITLFILTINQVVECKSSLYYSILNDYEKGIDYYKILNVTKDSTYSEIKKSFRKLSLKHHPDRNVEKSSHSLYILLNQAHSVLTTDETRKEYDELLVNGIPWHENYYGKYAYRYTGISHDLRHVLLGLIIVITIGKFVYQYNKHHSMIKRAKQTDQYKKRLAQLDGDEDEIQLVIQGADKPTISSLFIIQLFFIFPFKILKSIYTFIFINKFKFIQKTDEEKEEEYRLKMGYTKEDWEYHKKKSIERMEKLKQSGKYKKYLRSKNK", "length": 279 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55E25-1", "protein_name": "DRBM domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSNKSHTSEKVQLNEFLQKKKQPIPIYHTESKGSEHNKDFKSIVVVNGKQIESDWKKSKKESEKDCAKNILEFIETLDGYPIYFTPFSKDPPQNNKKIYDEKLQAVYNSVSSGIEGLNNNSFFTKIENNNNNSSSNNNNNLDHNHSNDSSHTSTDNNDNNSNNHNNNNNNQINIDLTMENVNISQSKTITNEGTLNNDNDNNNNSIQQQQHQPQPQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQCFDKDKTNLKKKKKIPFSYNTDLIEHIDLFKRQDFPQTYPSRTTYTDTGHTQQLQKQVFLLTEKIGLMELFYKKQIRVILKSHHNLETELSALKSFVEDCSVTPIEGLELYSIPVPLNPNAKPSAGTTPVLSKSETQNEIIQPTKPPTKPPASCLIKKKIPNVNMKATNKTTTTTSTSTSNSSTTIKTTDSFKNTTNNQHPNTLKPMVSKINQQTSDFIFPLPKPIIRRNPIGNGNLEKKIEKKNSKPNTIVLGVDTQSQSKTKITPSPTTPPPETTPTTPTTTATPTTPTTPTTPTTTATPPPTTTATPPPTTTATPPPTATTPPPTTATTTPPPPPIIATTKTTATATATTIPIDLNEIQIPIRSPQDLTVNQSMISTAMMIASAAQRNPKLTMKLKRKLEESPTLMSKLQKIQFEKEEEILCSQDLHSPIMSPQSPTHQPKTLEPLSPTKKSTQKSPPPTSPSPIVTRARASSNLLPIQNLISKK", "length": 733 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55E47-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIAKTQIKCTTIYAPAKSNERHEWYKENLTEEILHSDIITGDFNVDCSVDNNLNKYIKTIFDEFEFTEIKNGITFPRNKSTIDRVFVSKKILHLNPIVTTKEIKLKSDHNMVIIELKIPEYEQQKKGERLWRQNLETLKMNSTSLKINKTIKYYNKKFEENTSKWYKLNICEQWLKLKDEIKKLSINIEIRESNKTKNKLKELAEKLETAKDSRAIFLKEEINNILKEQVRIKQANQTNTHINNKETPSKYLTRRLKVQRKTNEIPQILDPSNNCLVTKNEDILEVARRYYENLYQKRECNEDTHHELLKTFNKRIDQKILDEINQPIEEYEIRLGIEKIQEGKAPGKDGLLPTFYKNHINEILPIISKLYNHFWNTTIPKDFKQGILITIYKNKGDPNNLDNYRPITLLNVDYKIYSKIINNRILKFLNKIISPFQTGFVPRRLLHDNIITLNSTIEIIKREINTKEDMEPIITFYDFEKAFDSISHNAILRTLAHLKLPLKMVLTIMNLLNESETSVYINNSLSKSFTSKRGTKQGDPISPTIFALVVECMATTIINDRCINGVTKETIKILQFADDTATIAYNFMDHFLMNEWIKKFCQATSAKINQTKCSCITFKWNTRTLYTVIKSNERYLGFDFNNKGIKSKINTISDNIRAKLVTWNSTSSTYMGRLIMAKTYALSQLTFHTYINTTPQHNSIENNIVKFVFNTKSKNSLSLQRRQNNYINGGLNLWNLKTRELAQKAWLFERYLHQRVSNTPSSYIKLWEEELKNNNNNKTTTKQNQLQLHWQCKQAWTQLKTPQNKQTHYEHLPKLKKIYEDMMTTQSPEHNKFIPTPGQKEIMTKINSKHLPFKEIKKIINMKGRDLLWRYTLKALPKIYNMPCQQCGEDETSEHIFFNCKAHIKNTQEIFNYTLTKSGHTTHTWNVKILNHLQIALVANLIAIIFDKIWHKRNKLIHDEKEIIIHRQQVIRELIKTQRAAWDRTQAVINKTLRIKSKQRPEEQNKLDSLISLKLLQFSRQWNSPLHAIELPKHLKKYNNSLSTFYK", "length": 1047 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55E48-1", "protein_name": "thioredoxin-dependent peroxiredoxin", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MTKLKVGNIAPDFEAKNYLGQIVTLKEFKEKSQPIVLYFYPKDNSPECQKSCEFRDKYQKSIEAGAEVIGVSSDGEDSHKSFVSKYSLPFTLLTDKHSKLAKLYGVNGILLPGRKTFIIDKHGFMAVFMMVYSVQLLMSMNL", "length": 142 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55ED8-1", "protein_name": "Decapping nuclease", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKQTLNVIGLINFIKKQRSFNKSPITITKPLEITRFSYEGNQLFPAKLKKFKNPTIDSDLLVGFQGPDSIESDSQTPLSLVLNKLIETKHDVSKSNFISFRNSFRKLFESMYDSEKWNIQVQRINSTIHLGMDNPTQDFHQLKNFHLKSMYSGNYFEKISTIDNNNNPNDNKHKYCSIIQSKLFNNNFILACEIDCWKKSIQNNNNNQNNNNNENNNNDDDDENYNIDDYVELKTSRDIEDSKANYQFRSKKLIRIWFQAYIAGVSKIFLGIRNDDFFLKKCLNFNTHDLPNQAINWNKDEMLIYGNEILEFIKNNTCSGKSYTLSFNYPIISLVESDSINIINDQYLQYYLNIPKNFENNYNQNNNQNNNNNNNNENNSDDTKNNNIQNNNENNNIQNNNENNNQNNNEKNQKRNFGEEKEIKGDENEERLSKKQKKLE", "length": 440 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55EZ2-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIAKTQIKCTTIYAPAKSNERHEWYKENLTEEILHSDIITGDFNVDCSVDNNLNKYIKTIFDEFEFTEIKNGITFPRNKSTIDRVFVSKKILHLNPIVTTKEIKLKSDHNMVIIELKIPEYEQQKKGERLWRQNLETLKMNSTSLKINKTIKYYNKKFEENTSKWYKLNICEQWLKLKDEIKKLSINIEIRESNKTKNKLKELAEKLETAKDSRAIFLKEEINNILKEQVRIKQANQTNTHINNKETPSKYLTRRLKVQRKTNEIPQILDPSNNCLVTKNEDILEVARRYYENLYQKRECNEDTHHELLKTFNKRIDQKILDEINQPIEEYEIRLGIEKIQEGKAPGKDGLLPTFYKNHINEILPIISKLYNHFWNTTIPKDFKQGILITIYKNKGDPNNLDNYRPITLLNVDYKIYSKIINNRILKFLNKIISPFQTGFVPRRLLHDNIITLNSTIEIIKREINTKEDMEPIITFYDFEKAFDSISHNAILRTLAHLKLPLKMVLTIMNLLNESETSVYINNSLSKSFTSKRGTKQGDPISPTIFALVVECMATTIINDRCINGVTKETIKILQFADDTATIAYNFMDHFLMNEWIKKFCQATSAKINQTKCSCITFKWNTRTLYTVIKSNERYLGFDFNNKGIKSKINTISDNIRAKLVTWNSTSSTYMGRLIMAKTYALSQLTFHTYINTTPQHNSIENNIVKFVFNTKSKNSLSLQRRQNNYINGGLNLWNLKTRELAQKAWLFERYLHQRVSNTPSSYIKLWEEELKNNNNNKTTTKQNQLQLHWQCKQAWTQLKTPQNKQTHYEHLPKLKKIYEDMMTTQSPEHNKFIPTPGQKEIMTKINSKHLPFKEIKKIINMKGRDLLWRYTLKALPKIYNMPCQQCGEDETSEHIFFNCKAHIKNTQEIFNYTLTKCGHTTHTWNVKILNHLQIALVANLIAIIFDKIWHKRNKLIHDEKEIIIHRQQVIRELIKTQRAAWDRTQAVINKTLRIKSKQRPEEQNKLDSLISLKLLQFSRQWNSPLHAIELPKHLKKYNNSLSTFYK", "length": 1047 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55F94-1", "protein_name": "Dynamin-like protein A", "gene_name": "dlpA", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSVFKKKDKSDDKKKKHDEETPQGTFQPASQSTSNTNLNSLASSVNNGASVGSTNGSTPNNSNGSTPTYNHNNSAEELEKQKKEEDEKRKKSELEAAAAVVAKKKEDEEKQRKEQVELERKRRDEEIRRTNAAAANAANKELNEQVEISSLEQMGKLDPSSTIHDMFSFFPNEVYNSYEKLQYFSRDLNTAVSHPEIVFVGPRSSGKSSLIEAFIGRALNIVGGGNIVGVGGSNANGCSKRVLYLQFTNNIDFEVPKVTIKKDNTIKEFDHDIIVSIEQLNENLAKRNQLTNDYIEEPIYVSIESRTTLNLTLIDSPGLLFDQSQAESNKIESIVSSLLRPSHRLIIAVESCSQDWKSMSMGQYLKKIDPELSRSTFVFTKFHHTVRGFSSTRDINKYLSGTVPDIKGFFVTLPNHQVRASYSEANRFQEKIYQAHKRDMHALEQLQYDKRYERTIGVAPLRRYILNIVWKSYQDTIPRILKHLRSKRQTAEATLNELQKQSSSLDSTKLRSIASNYTVTFLQITEKLLSGTSEGNPSANGQTLDEEKSQQGDCGEWVDAYKEAIYIDPEEWNIPYWSSKLYGGQQLERLMAEFKAVCDNSKISEVKMDDIATASGINKLNNIPNYAWAASDLTSLISRDTFVPLIEQLCERAMYIMKRLTDIADKVIDSRRKSRCIGSSPFGGNGLNNINSGGNNGININDRLSNTDMDSLDQYPFFTHHVKNLYYDFVHRAAKGCKEKCMDEFYSSRTIYWELTEHPDSSLPSIRNDHHETKTAVCQLATKLFDSIRQRITKNVLLKLYNFFLVPMQTDLWNEIQAQITCLSNEQLEQLFEVQATREQLKQEEKKQQQILEKYSQIDEQFLKAASLFCRPLSNPTPSA", "length": 880 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55FX4-1", "protein_name": "SET domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MDINSNHIKKINDFKDKGNKEFNKEKNKDKLNKRAITYFQLGIKYFNDEKHKIEINDQINKLISILYSNLSLMYLKGDEIILSLEASNKSIEFNNQNSKAFYYQSICKSYLCDYKGSMESIDKAISISKQDEKVVQQRNRLIEITNNKVKEDVYFENVLKNQKLENVAYENSIEKGRYLISKRLIKRGEEILRIAPFSFSLNGKYVSKFCGVCYQKKSIDNLLKCKDCDDFAICKECKAPNEPLSKYHPNDLCVLYKLNNEYYKMNNFEIANEDNKERGLTDERRLYINTIYNIFKNKTNNKAVVEVDNAISSSVIDVLNLSKKLLNHTNESQRAYSDSTKMKTDILELIFKSFYGANTLKKDEISNIIRIVDCNSHGYSDVISQKKKASGLYPFSCYTNHSCIPNSDYFIDKHGVMVLYASSDIQESEAITISYIYFLNRVEKRRKDLLNGHNFFCTCDQCSFQSSLTEEVCDKCNEIIPSTIGNSNLVYKEPKSLKETGFNYICPKGHTKSSLVYDIDNDQLYPTIAENYSKCKDLRNFRKINIFKEMLENRDFVKKLTPREFEVTPLAKYIANPKKSNSMLFEELINLVRGSVECGLTKSIEESNYSTYLVYDYYDLYKSLLLESKPQILKLNSIRDIIIKLLTPMVYNQNKPRIDKKLNKHLSNKINLKKNK", "length": 676 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55G93-1", "protein_name": "Tubulin-specific chaperone D", "gene_name": "tbcd", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MENSEDISLNSSEKSIESSVVNLEDQQQSQQQTQQQTCQKTFVQEAPELTILIDKLIQLKHSNKDELISNTTRIIYIIDQYLEQPTLLDIHLNDIIQPLINFIKSNYINNSNNNNTTTTTTTIMTETEIVIKKLSIKNSFRIIYVLSKVRGFKTIVKLFQHEAIDLLPVLDQLEISYHQWVNINKQRDRLNEISVSYSSGINLKNYIKPEEESEQEVVDENNNNINNNHNIDDEYNENIISWEEVYVLALWVSLLVIIPFKFSSLDSASSGTASAAGDGGDGDGDGQLKSISSRILKLGKLALSDVSKIRDSFSELLSKLLNRPDMKFEQKQFIKWCTNSIQLISNNNNNNNQNNSSNNNILLIIGIYSTLATMFKKGNRLDFLPIDMNLYEKIMEANKYLSLSGSERITKKIFLKLLQRIAIIMLPPVSASWRYQKIIKPLLLKGELIKQINNNNNNNNNENNNEEGEEEEEEIPEEIDEILEEIMKSLKDKDTIIRWTSAKAIGRIVNLLPKDMGDQVIGLVIDQMFEKNEFIDADPSAWHGGCLALAELARRGLLLPERLDVVVPLVIRALFFDIIKGTYSIGSHVRDSACYLCWALARTYHNSILSPYLLPICRNLVVVSLYDREINCRKSASAAFQEMVGRHQGLVPNGIEIVTSADFFTVGNKNNSFTSLTTFIGKFQIDYYPIVIKHLATIKIYNWDLEIRQLASKSIHLLTNINPNDIVSNYLPLIIPNTQSDLVHVKHGASLAISEILISLFENNNINLLSDNLKMMILMTIKNTKNEKLFKGKGGVLIRIGMCKIIYSICLVEFSLDKNLSEIKKPTESTSTNGNEDRAAALKLKIAMLKAKTASQINKPIITPPSSKSTTNNNNNNNNNNLNDNEIAFNIILGYLNENLNHPNEEVQKEASKAFELLFSKYISSNEKISLLLELIDSHCKTLKFDINRSARRGSSLLLGSLPFNSANLSYDLLSKVVNELILSIFQDDPKFKDIETRVNSISSLYKIGIYILNLIFKNQENEQKEEEDFKKSKNYNLFIKIWNCLGLATNDYSIDKRGDIGSWVRELSCKVLFDFIKFIITNQNSSTTTTTASTTDLSIENLINEKMITEFICKLFQLSGEKLDKIRDVACKIIHELLWIENPSSINNIPHKEELKKIIVKDQDVHFNWFRTEESLPLICKVLKFNCYLYPLLFGLFSSLGGTSKYLINDSIQSIKQYFSSFDNDEKERFEKIISFSKAILEITNNTTQRMIQPTFRSIYNLLSTHIFDFLIINNLNEQSIFETILFNCYQIIESNQDDIYLLLNSIELFSYFFIQFENNNNEYIKDYSLKALLLLLSNLKYPKVRKLASDQLKKSTRLFINNNGDDETPSLIKSLIFNTKWDDSVDLIIEPLKSLLLLLNQKHLLELLSENPTKKPIPLAPPITSIEELKDKIQNPHKQSDDNNNNNNGELINNNTENNNNNNFDDNLPEDSQDLMEI", "length": 1480 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55GP8-1", "protein_name": "Rho GTPase-activating protein gacO", "gene_name": "gacO", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSKLPPPPVQSSPQGFQLPSLHSVQLKPVRPPPQPTQQQLASNTSPREVGTSLSPQSPSNNINPSSSSSSPSSSIRQSPSSSPNVARKVPPTPTNNNGGPPTTTTTTTTTMPPPPAFIKKLSPSSSPILPKRIVSSPPLNGNTAPPPPPIVHLPPPPPTNLPPPPTLSPSSSTTTSPSSSSLNLSGGVPLPPRILRNSDGSANNNNNSNNNSNNNINSLNLSTSGGIPPPPSFFNNNNNNNNNSGSFVNSASSNGSPSLQSQNSVGYFKPPPPPVPTRSASLDPKQMGQFIKPQQNQNNSNNINNINNNNNNIILPPPPNININNNNFVPYIPSNNNQQQSTTPPPIVSISPLKRNSIDNSVVNKRLSQDLNTMLVNRLQHGLSPPVATPFFDDKILGSASKSAELKEKRDQEERERRERERIKKEKEDSEKKEKKEKKGKEEQEKKDKKKKEEQEKKDKKKKEEEEKKSKSSSSSSSSSKKSSSDNTIVNQNIFNNTLSQIMENQRDAQSLSPSSLPYPLILKLLTESIMSLNGPYTEGIFRITGSGTEVNRLKKQINEHDFSLDTQDPHVLAGLLKLWLRELVHPIIPSELYNDAIKSRSKEEVSRIISLIPDQNKEVLNFLIPFLKNVSQPHYAQYSKMDIDNVAMVFSPGLLRSTVLTTDLLLNSQYEKDFVKCLIEMSP", "length": 684 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55GR8-1", "protein_name": "Thiamin pyrophosphokinase thiamin-binding domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEKQEEEVQQQQQQQQQQQQPDKNNKETITWDVAEYGGYLFDKKLKAHNPLNHQMPLQYHHSQSTPHIPSSLSTSSTTSIKKPSSSLSDDESGGSSSSTPHSSNTPRKQFSFDDHCALILANQKLPKKLVDYFWDKCSVRICADGGANRLYSLGTKINQSSRWIPDYIKGDLDSLHEGVSDFFSKKGSSIVLDSSQDTSDLQKCFELIIDLEKGSGIKYRKIFILGGLGGSFSHEFANVNTLFDHPGRKIILASKDNLAWLLSSTYNHNIICRSETKCSLIPLSSKASQVTTSGLKWNLVKQSLNFGELISTSNVSLDNKVCVETSNPLIFIVDINP", "length": 337 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q561S0-1", "protein_name": "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial", "gene_name": "Ndufa10", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MALRLLRLVPASASARGLAAGAQRVGRIHTSVHCKLRYGLLASILGDKTTKKLHEYSRVITVDGNICSGKNKLARDIAEQLGMKHYPEAGIQYSSSTTGDGRPLDIEFSGSCSLEKFYDNPKSNDGNSYRLQSWLYASRLLQYSDALEHLLSTGQGVVLERSIYSDFVFLEAMYNQGFIRKQCVDHYNEIKRLTLPEYLPPHAVIYIDVPVSEIQSRIQKKGDPHEMKVTSAYLQDIEDAYKKTFLPKMSEICEVLVYSSWEAEDSTKVVEDIEYLNYNKGPWLKQDDRTFHNLRMLVQDKREVLNYTTVPVYLPEITIGAHQGSRIYDSFRELPGRKYAPGYNADVGDKWIWLK", "length": 355 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q568T5-1", "protein_name": "Chondrolectin", "gene_name": "chodl", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MRATLRILCALTFLVSCSRGARVVSGQTVCQGNPEHPCYKIAYFKDVSSRVAFWEALQACEMDGGSLLSIENTAEQKHIEHLLRELSVSSSTGPASITDGDFWIGLTREEGDNAQEPGAFASCPNLYRWTDGSVSLFRNWYADEPSCGGEACVVMYHQPTALAGPGGPYLYQWNDDRCNMKHNFICKYEPESHLVKVQSDRPGGHDVDLSTEDKEDRRTPPTDEDESPRLIIAGPSSMLLIYVIIPTIPLLLLILVASGTCCFQMLSKSKPRTKTSVNQSTLWISKTPKIDSGMEV", "length": 296 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q5HYN5-1", "protein_name": "Cancer/testis antigen family 45 member A1", "gene_name": "CT45A1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTDKTEKVAVDPETVFKRPRECDSPSYQKRQRMALLARKQGAGDSLIAGSAMSKAKKLMTGHAIPPSQLDSQIDDFTGFSKDRMMQKPGSNAPVGGNVTSSFSGDDLECRETASSPKSQREINADIKRKLVKELRCVGQKYEKIFEMLEGVQGPTAVRKRFFESIIKEAARCMRRDFVKHLKKKLKRMI", "length": 189 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q5I0J8-1", "protein_name": "PHD finger protein 11-like", "gene_name": "Phf11l", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAQEEPGGSNSVLNGDANSDKKMEKWTCALCPEGHDWSVIYFEPSSNIAAHENCLLYSSGLVECGPHDPRNPARSFAVKSVKKEIWRGRRLKCSFCNNKGATVGCDLQSCPKNYHLHCAKEDRAILQVDEDYGTYKLFCQRHAPGGQEPTQVDAAVKASFLKKCLEAGLLTELFEQIQQKMISIHGRFMDDTASESDYEGIKILLFDCGLFKDTLIKFEEAIKSKACECEERLNQMKQQLELLADLQQNLRSFQECGVLDPSGSTSGSLLPPEDHQCRCQESPEVQAGSGDSL", "length": 293 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5J3E6-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vom1r12", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDSKDLAIGVIFILQCSMGILRHFILLSYYLMLHYNKHSLKPIDLILMNMFIANFLIIFPKSMLQTVEAFGIKLLFSVFVCKFLLYIERVGRSVSIATVCLLSVFQAITISPRNSCLYGLKVKVPKYISLSIFLCWALYFVVNMILPVYAYIKWSSNNMTYKRTLKYCFSVGHDEFTGSFFTILFVFPEVFLAILIVWSGSSMVVILYRHKQQVQHIYCNYASTRTSPESRATKSIVVLVSVFICFYSISSILYGCIALFCDNSWSLINIANIISLCFPVLGSFVVSHNPDFPRFSLSWIRNTRRV", "length": 306 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5J3E9-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vom1r15", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVNDRMESKDLAVGVIFILQCSMGILRHFTLLSYYLMLHYNKHTLKPIDLILMNMFIANFLLIFSKSVLQTVEIFGMELFFNVFVCKFLLYIERVGRSVSVATVCLLSVFQAITISPRNSCLNGLKVKVPKYINLSIFFCWPLYFVINMILPVYGCIKWNSNNMTYKRSVKYCFSIGHDELTSSIFTILFVFPEVFLAILIVLSGSSMVVTLYRHKQQVQHIYCNYACTRTSPESRATKSIVVLVSVFICFYSVSSILYGCIALFCDDSWWLINIAHIISLCFPIFGSFLVSHNPALSRFSLSWIKNTRRV", "length": 311 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5J3F0-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "LOC100911184", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDFWNLAIRIIFLSQIIIGILGNVSLLFYYLVLYYREFTLKSTELILMHLMVANIIIIFSAGVPQTMTIWGMKQFLNDFGCKLLLYIHAVGRSVSICTTCLLSVFQAMTIRPQKFCGNDHKVTMERYLGCFISFLWVLYFLVNFIFLVYTYIKKNSNNETRKRDFGYCSTVGSDKISDSLYATLVMCPEVFFSVLIAWSSGSMIVILYRHKQKVKYIYSTHVSRRDYPESRATQNILAQMFTFLAFYTLSSTLRGSIALLSNHSWWLMNINHFTSLCFPSFGPFVLMSHYSIVSRFILFWLRKNCSNFLL", "length": 310 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5JQC4-1", "protein_name": "Cancer/testis antigen 47A", "gene_name": "CT47A1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSATGDRHPTQGDQEAPVSQEGAQAEAAGAGNQEGGDSGPDSSDVVPAAEVVGVAGPVEGLGEEEGEQAAGLAAVPRGGSAEEDSDIGPATEEEEEEEGNEAANFDLAVVARRYPASGIHFVLLDMVHSLLHRLSHNDHILIENRQLSRLMVGPHAAARNLWGNLPPLLLPQRLGAGAAARAGEGLGLIQEAASVPEPAVPADLAEMAREPAEEAAEEKLSEEATEEPDAEEPATEEPTAQEATAPEEVTKSQPEKWDEEAQDAAGEEEKEQEKEKDAENKVKNSKGT", "length": 288 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q5QNN9-1", "protein_name": "Trace amine associated receptor 12e", "gene_name": "taar12e", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MMSLNETQTENILLCYPLLSNSCPKLHRLAVVQVGLYVFLLLMILTTVFGNLLIIISISHFKHLQSPTHLIVRSLAACDCLLGLLVMPYSMVRSVEGCWYLGDVVCKVHSSLDMTFCISSLLHLGLISVDRYWAICDPLRYRLRVTNITVTVFIVFIWLFSFVYSFYVVFSGVNTVGLETFIMQVYCVGSCVLYFNKQWGLICPILVFFLPGAIMSSLYMKIFHVARKHAKVMSERVTGGLKSQSSAQRERKAAKILAIVMGVFLFCWLPFFTVNALDPFFNFFTPADIFDAVIWFAYLNSTCNPLIYGFFYPCFQKAFKILIFTYICGVRNLDTFA", "length": 337 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q5QNP0-1", "protein_name": "Trace amine associated receptor 12g", "gene_name": "taar12g", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTSNESENIQLCYPLLSNSCPKLHRLAVVQVGLYICLLLMILTTVFGNLLIIISISHFKHLQSPTHLIVRSLAACDCLLGSLVMPNSMVRSVEGCWYLGDVVCKVHSSLDMTLCISSLLHLGLISVDRYLAICDPLRYRIRVTNTTVTVFTVFIWLFSVVYSFYVKFSGITAVGLEMLILQTYCVGRCVVFFNKQWGLICPVLAFFLPGAIMSSLYMKIFHVARKQAKVISERVTGGLKSQSSAQRERKAAKTLAIVMGVFLFCWMPFFTLTALDPFFNFLSSADVFDALFWFAYLNSACNPLIYGFFYPCFQKAFKILIFTYICGVKKANTLTFE", "length": 336 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q5R1F6-1", "protein_name": "T cell receptor alpha variable 5N-4", "gene_name": "Trav5d-4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKTYAPTLFMFLWLQLDGMSQGEQVEQLPSILRVQEGSSASINCTYENSASNYFPWYKQEPGENPKLIIDIRSNMERKQTQGLIVLLDKKAKRFSLHITDTQPGDSAMYFCAAS", "length": 114 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q5RKI7-1", "protein_name": "Solute carrier family 7 member 13", "gene_name": "Slc7a13", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAMDIEKKIYLKRQLGYFWGTNFLIINIIGAGIFVSPKGVLQYSSMNVGVSLCVWVFCAVLSMTSTLCAAEIGITFPYTVAHYYFLKRCFGPFVAFLRLWTSLFTGPGVLASQALLLAEYGIQPFYPSCSAPAVPKKCLALAMLWIVGILNSRGVKELSWLQTVSMVLKMGILSFISLSGLFLLVTGRKENVRRLQNAFDAEFPEVSRLIEAIFQGYFAFSGGGSFTYVAGELKEPSKTIPRCIFTALPLVTVVYLLANLSYLTVLSPQELLSSDAVALTWTDRVIPQLTWSVPFAISASLFSNLVTSVFETSRTSYIASRNGQLPLLCSTLNVHSSPFIAVLLDVSMGSIAIVLTNLIELINYLFFVFSIWTVLSVIGILKLRYQEPNLHRPYKVFSPFLFITAAISLSMVLIPLIKSPKMQYIYVFLFFLGGLLFYVPLIHFKLKLIWFQKLTCYLQLLFNICIPDVSDEHVAEEES", "length": 479 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5XHX8-1", "protein_name": "Sperm microtubule associated protein 2", "gene_name": "Spmap2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGELGEHRSRSSLLSIPVLDTKTSGGSEYRESDGSLDLQSTLFEDHWLQSSQATTERNTDDPEEEIPPEEMVGEELPEVSNLEDSLRRDLEVEVVGMSHLSINERTTPTTSSAKCRKKKNHRLLELAKPKFNWQCLKDRTGRCCKGHVWISPRKTNLQFCLYWPSVYWTERFIEDTTLTITVPEVSRRVEELSRPKRFYQEYYNNNRTTPIWPIPRSTLEYQASNRLKRLATPKIRNNIWSINMSEVSQVSRAAQMAVPTPRTLRLAKPRAPATLLEEWDPMPKPKPYVSDYNRLLQLATPKALSEKCVPDRSPQWEVLNVTKNAVASSRIISLAQPKIRKDLNEGYNPYYISPASLVAQASPRIYELAVPKHITKKV", "length": 378 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q63550-1", "protein_name": "BPI fold containing family A, member 2F", "gene_name": "Bpifa2f", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFQLGSLVVLCGLLIGTSGSLFDIFQNPELDVESVWSEINYRIRYALETMDLDMLADYLSKRGIELKIKDLRILNLNHEVSPNGDEVTLKMPMALNASLSLPARDLTTDVSISMEAITSFAIEKDPKTGRRVLNMQRCSLNTDNTSISLLNRKSNFVNLALDSALYLIKRGLTLPVRRQLCPVLQLIISNTFHPDEISNPQTAIST", "length": 206 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q64583-1", "protein_name": "Cytochrome P450 2B15", "gene_name": "Cyp2b15", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MELGVLLLLTFTVGFLLLLASQNRPKTHGHLPPGPRPLPFLGNLLQMNRRGLLRSFMQLQEKYGDVFTVHLGPRPVVILCGTDTIREALVDQAEAFSGRGTVAVLHPVVQGYGVIFANGERWKILRRFSLVTMRNFGMGKRSVEERIKEEAQCLVEELKKYKGALLNPTSIFQSIAANIICSIVFGERFDYKDHQFLRLLDLIYQTFSLMGSLSSQVFELFSGFLKYFPGVHKQISKNLQEILNYIDHSVEKHRATLDPNTPRDFINTYLLRMEKEKSNHHTEFHHQNLVISVLSLFFTGTETTSTTLRYSFLIMLKYPHVAEKVQKEIDQVIGSHRLPTLDDRTKMPYTDAVIHEIQRFADLIPIGLPHRVTNDTMFLGYLLPKNTEVYPILSSALHDPRYFDHPDTFNPEHFLDVNGTLKKSEAFLPFSTGKRICLGEGIAQNELFIFFTAILQNFSLASPVAPEDIDLSPINSGISKIPSPYQIHFLSRCVG", "length": 495 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q66X01-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 9C", "gene_name": "Nlrp9c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVDSSSYGLLQYFQKLSDEEFQRFKELLQKEQEKFKLKPLSWTKIKNTSKEDLVTQLYTHYPRQVWDMVLNLFLQVNRKDLSTMAQIERRDKQNKYKEFMKNLFQYIWTSETNTYMPDRSYNTIIDRQYKALLDIFDSESDPATAVVLGTRGKGKTVFLRKAMLDWASGVLLQNRFQYVFFFSVFSLNNTTELSLAELISSKLPECSETLDDILSNPKRILFVLDGFDYLKFDLELRTNLCNDWRKRLPTQNVLSSLLQKIMLPECSLLLELGESSCSKIIPLLQNPREIIMSGLSEQSIYFYCVSFFKIQLGVEVFKDLKKNEPLFTLCSNPSMLWMICSSLMWGHYSREEVISSSESTSAIHTIFIMSAFKSIFGLGSSKYKRFKLKTLCTLAVEGMWKQVYVFDSEDLRRNKISESDKTVWLKMKFLQIQGNNIMFYHSTLQWYFATLFYFLKQDKDTYHPVIGSLPQLLGEIYAHKQNQWTHAQTFFFGIATKHVITLLKPCFGNISFKTIRQEIIRYLKSLSQPECNEKLVHPKKLFFCLIENQEERFVSQVMNLFEEITVDISDSDDLGAAEYSLLRASKLKNLHLHIQKKVFSEIHDPEYGSLENFKLDQKFSAINWTMLSILFCNLHVLDLGSCHFNKKVIEVLCNSLSPTPNMPLTVFKLQRLLCSFMTNFGDGSLFCTFLQIPQLKYLNLYGTDLSNDVVEMLCSALKCSTCRVEELLLGKCDISSEACGIMATFLINSKVKHLSLVENPLKNKGVMFLCKMLKDPSCVLESLMLSYCCLTFIACGHLYEALLSNKHLSLLDLGSNFLEDIGVNLLCEALKYPNCTLKELWLPGCYLTSECCEEISAVLTCNKNLKTLKLGNNNIQDTGVKRLCEALCHPKCKVQCLGLDMCELSNDCCEDLALALITCNTLKSLNLDWNALHHSGLVMLCEALNHKKCKLNMLGLDKSSFSEESQTFLQAVEKKNNNLNVLHFPWVEDELKKRGVRLVWNSKN", "length": 1004 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q675C0-1", "protein_name": "Taste receptor type 2 member 102", "gene_name": "Tas2r102", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEPVIYSFATLLIHVEFIFGNLSNGFIVLSNFWDWVIKRKLSTIDKILLTLAISRITLIWEIYTWFTSVYGPSSFAIGMKLQILYFTWILSSHFSLWFATALSIFYLLRIANCSWKIFLYLKWRLKQVIVGMLLASLVFLPGILTQRTLEERPYRYGGNTSEDSMETDFARFTELILFNLTIFSVIPFSLASISFLLLIFSLWKHLRKMQLSSRGHGDPSTKAHTNALRIMVSFLLLYSIYFLSLLLSWIAQKHHSKLVDIIGIITGLMYPSAHSFILILGNSKLMQTSLWILSHLRCRLKGENILNPSGNQVTSCYIFCIANKSVS", "length": 327 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q68FP3-1", "protein_name": "C-C motif chemokine 6", "gene_name": "Ccl6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRHSKTAISFFILVAVLGSQAGLIQDTVKEDRPFNPTIIHQGFQDSSDCCFSYASQIPCSRFIYYFPTSGGCTKPGIIFVTRKRKRVCANPSDQRVQTCISTLKLGPRSGNSAIA", "length": 115 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6EKJ0-1", "protein_name": "General transcription factor II-I repeat domain-containing protein 2B", "gene_name": "GTF2IRD2B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAQVAVSTLPVEEESSSETRMVVTFLVSALESMCKELAKSKAEVACIAVYETDVFVVGTERGCAFVNARTDFQKDFAKYCVAEGLCEVKPPCPVNGMQVHSGETEILRKAVEDYFCFCYGKALGTTVMVPVPYEKMLRDQSAVVVQGLPEGVAFQHPENYDLATLKWILENKAGISFIINRPFLGPESQLGGPGMVTDAERSIVSPSESCGPINVKTEPMEDSGISLKAEAVSVKKESEDPNYYQYNMQGSHPSSTSNEVIEMELPMEDSTPLVPSEEPNEDPEAEVKIEGNTNSSSVTNSAAGVEDLNIVQVTVPDNEKERLSSIEKIKQLREQVNDLFSRKFGEAIGVDFPVKVPYRKITFNPGCVVIDGMPPGVVFKAPGYLEISSMRRILEAAEFIKFTVIRPLPGLELSNVGKRKIDQEGRVFQEKWERAYFFVEVQNIPTCLICKQSMSVSKEYNLRRHYQTNHSKHYDQYTERMRDEKLHELKKGLRKYLLGSSDTECPEQKQVFANPSPTQKSPVQPVEDLAGNLWEKLREKIRSFVAYSIAIDEITDINNTTQLAIFIRGVDENFDVSEELLDTVPMTGTKSGNEIFLRVEKSLKKFCINWSRLVSVASTGTPAMVDANNGLVTKLKSRVATFCKGAELKSICCIIHPESLCAQKLKMDHVMDVVVKSVNWICSRGLNHSEFTTLLYELDSQYGSLLYYTEIKWLSRGLVLKRFFESLEEIDSFMSSRGKPLPQLSSIDWIRDLAFLVDMTMHLNALNISLQGHSQIVTQMYDLIRAFLAKLCLWETHLTRNNLAHFPTLKLVSRNESDGLNYIPKIAELKTEFQKRLSDFKLYESELTLFSSPFSTKIDSVHEELQMEVIDLQCNTVLKTKYDKVGIPEFYKYLWGSYPKYKHHCAKILSMFGSTYICEQLFSIMKLSKTKYCSQLKDSQWDSVLHIAT", "length": 949 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q6NXT2-1", "protein_name": "Histone H3.3C", "gene_name": "H3-5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MARTKQTARKSTGGKAPRKQLATKAARKSTPSTCGVKPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFNTDLRFQSAAVGALQEASEAYLVGLLEDTNLCAIHAKRVTIMPKDIQLARRIRGERA", "length": 135 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q6P3W6-1", "protein_name": "NBPF family member NBPF10", "gene_name": "NBPF10", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVVSAGPWSSEKAEMNILEINETLRPQLAEKKQQFRSLKEKCFLTQLAGFLANRQKKYKYEECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDASRSLYEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDEDEDEDVQVEEAEKVLESSAPREVQKAEESKVPEDSLEECAITCSNSHGPCDSNQPHKNIKITFEEDEVNSTLVVDRESSHDECQDALNILPVPGPTSSATNVSMVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLSGFLANQQKKYKYEECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLKEKLREGRDASRSLNEHLQALLTPYEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSAPREMQKAEEKEVPEDSLEECAITYSNSHGSYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKGPEVLQDSQDRCYSTPSGCLELTDSCQPYRSAFYILEQQRVGLAIDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGFAFDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDEEEEEDQDPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLEEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGFAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDEEEEEDQDPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLEEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGFAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDEEEEEDQDPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQDPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDEEEEEDQDPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGYLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELCDSCQPYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDKIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLNGVLMEVEEREVLQDSLDRCYSTPSMYFELPDSFQHYRSVFYSFEEQHISFALYVDNRFFTLTVTSLHLVFQMGVIFPQ", "length": 3795 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q6UGQ3-1", "protein_name": "Secretoglobin family 2B member 2", "gene_name": "Scgb2b2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKGTLLLLALLVTGELGFQRTEACIPFFGVYLGILSGNRIGLHTELAPFDPTVEEKEAFEKIQDCYEEEGLKAKTEDMKLMTTILFSSECRSYYTKEVLKNILVKFSKKLTHGS", "length": 114 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q6YCH2-1", "protein_name": "TD and POZ domain-containing protein 4", "gene_name": "Tdpoz4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSGELEAKSRGDTQSHEQKLCYRWTISNFSFFVEETEEYITSLVFSLEDNDKMTWCLRVYPTGVDEKNKDYVSLYLILLSCEKGSVWAKFEVCILNAKGEKCNTERIPSFSRIQPHQPFGFEKFITRDSFLSPAQVLTPDDKFTLLCKVSVLQDSFSISGQNPRPAIKVTRCTLENDVGELWENPLFTDCSLLVAGHEFRAHKAILAARSPVFRAMFEHEMEERLTNCVEIHDLDPQVFKEMMGFIYTGKVPHLHSHSMACDLLAAADRYGLEDLMVMCEDALCRSLSVENAAHTLIVADLHSTEHLKTQALDFIIVYASEVSKTSGWMSMVESHPRLVAEAFHSLASAQRVFWALPFKQLKWSLRPTQL", "length": 370 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q6ZMA2-1", "protein_name": "Olfactory receptor", "gene_name": "Or1o1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MNCTQSPGFILLGLSSDPEKWQLFFSIFLALYLLGFLGNLLLLLAIGADVHLHTPMYFFLSQLSLVDLCFITTTAPKMLEALWTGDGSISFSGCLTQMCLFGVFADMDNLLLAVMAIDRYAAICQPLLYPLLMTPCRCGVLACGSWGIAHCASLVYTLLLSQLSFHSNQEIPHFFCDSRPLLWLSCSDTHLNEFLMMVLSALLGISALLCIVSSYGCIFCAVARVPSAKGRRKALATCSSHLSVVLLFYSTVFATYLKPPSTSHSSGEVVAAVMYTLITPTLNPFIYSLRNKDVKNSLKKLLNMEKPLD", "length": 309 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q70YC5-1", "protein_name": "Protein ZNF365", "gene_name": "ZNF365", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MQQKAFEESRYPWQESFENVAVCLPLRCPRCGDHTRFRSLSSLRAHLEFSHSYEERTLLTKCSLFPSLKDTDLVTSSELLKPGKLQSSGNVVKQKPSYVNLYSISHEHSKDRKPFEVVAERPVSYVQTYTAMDLHADSLDGTRSGPGLPTSDTKASFEAHVREKFNRMVEAVDRTIEKRIDKLTKELAQKTAELLEVRAAFVQLTQKKQEVQRRERALNRQVDVAVEMIAVLRQRLTESEEELLRKEEEVVTFNHFLEAAAEKEVQGKARLQDFIENLLQRVELAEKQLEYYQSQQASGFVRDLSGHVLTDISSNRKPKCLSRGHPHSVCNHPDLKAHFHPKGRNHLKKAKDDRASMQPAKAIHEQAESSRDLCRPPKKGELLGFGRKGNIRPKMAKKKPTAIVNII", "length": 407 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q71LE2-1", "protein_name": "Histone H3.3", "gene_name": "H3-3A", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MARTKQTARKSTGGKAPRKQLATKAARKSAPSTGGVKKPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSAAIGALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGERA", "length": 136 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q7KR10-1", "protein_name": "Probable cytochrome P450 12d1 distal, mitochondrial", "gene_name": "Cyp12d1-d", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MNTLSSARSVAIYVGPVRSSRSASVLAHEQAKSSITEEHKTYDEIPRPNKFKFMRAFMPGGEFQNASITEYTSAMRKRYGDIYVMPGMFGRKDWVTTFNTKDIEMVFRNEGIWPRRDGLDSIVYFREHVRPDVYGEVQGLVASQNEAWGKLRSAINPIFMQPRGLRMYYEPLSNINNEFIERIKEIRDPKTLEVPEDFTDEISRLVFESLGLVAFDRQMGLIRKNRDNSDALTLFQTSRDIFRLTFKLDIQPSMWKIISTPTYRKMKRTLNDSLNVSQKMLKENQDALEKRRQAGEKINSNSMLERLMEIDPKVAVIMSLDILFAGVDATATLLSAVLLCLSKHPDKQAKLREELLSIMPTKDSLLNEENMKDMPYLRAVIKETLRYYPNGFGTMRTCQNDVILSGYRVPKGTTVLLGSNVLMKEATYYPRPDEFLPERWLRDPETGKKMQVSPFTFLPFGFGPRMCIGKRVVDLEMETTVAKLIRNFHVEFNRDASRPFKTMFLMEPAITFPFKFTDIEQ", "length": 521 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q7M715-1", "protein_name": "Taste receptor type 2 member 117", "gene_name": "Tas2r117", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKHFWKILSVISQSTLSVILIVELVIGIIGNGFMVLVHCMDWVKKKKMSLVNQILTALSISRIFQLCLLFISLVINFSYTDLTTSSRMIQVMYNAWILANHFSIWIATCLTVLYFLKIANFSNSFFLYLKWRVEKVVSVTLLVSLLLLILNILLTNLETDMWTNEYQRNISCSFSSHYYAKCHRQVLRLHIIFLSVPVVLSLSTFLLLIFSLWTHHKRMQQHVQGGRDARTTAHFKALQTVIAFFLLYSIFILSVLIQIWKYELLKKNLFVVFCEVVYIAFPTFHSYILIVGDMKLRQACLPLCIIAAEIQTTLCRNFRSLKYFRLCCIF", "length": 330 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q7M719-1", "protein_name": "Taste receptor type 2", "gene_name": "Tas2r115", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MCAVLRSILTIIFILEFFIGNLGNGFIALVQCMDLRKRRTFPSADHFLTALAISRLALIWVLFLDSFLFIQSPLLMTRNTLRLIQTAWNISNHFSIWFATSLSIFYLFKIAIFSNYLFFYLKRRVKRVVLVILLLSMILLFFNIFLEIKHIDVWIYGTKRNITNGLSSNSFSEFSRLILIPSLMFTLVPFGVSLIAFLLLIFSLMKHVRKMQYYTKGCKDVRTMAHTTALQTVVAFLLLYTTFFLSLVVEVSTLEMDESLMLLFAKVTIMIFPSIHSCIFILKHNKLRQDLLSVLKWLQYWCKREKTLDS", "length": 310 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q7RTZ2-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 1", "gene_name": "USP17L1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGDDSLYLGGEWQFNHFSKLTSSRPDAAFAEIQRTSLPEKSPLSSETRVDLCDDLAPVARQLAPREKLPLSSRRPAAVGAGLQNMGNTCYENASLQCLTYTLPLANYMLSREHSQTCQRPKCCMLCTMQAHITWALHSPGHVIQPSQALAAGFHRGKQEDVHEFLMFTVDAMKKACLPGHKQVDHHCKDTTLIHQIFGGCWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVKQALEQLVKPEELNGENAYHCGLCLQRAPASNTLTLHTSAKVLILVLKRFSDVAGNKLAKNVQYPECLDMQPYMSQQNTGPLVYVLYAVLVHAGWSCHDGHYFSYVKAQEVQWYKMDDAEVTVCSIISVLSQQAYVLFYIQKSEWERHSESVSRGREPRALGAEDTDRRAKQGELKRDHPCLQAPELDEHLVERATQESTLDHWKFLQEQNKTKPEFNVGKVEGTLPPNALVIHQSKYKCGMKNHHPEQQSSLLNLSSTTRTDQESMNTGTLASLQGRTRRAKGKNKHSKRALLVCQ", "length": 530 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q7TMR7-1", "protein_name": "Monocarboxylate transporter 7", "gene_name": "Slc16a6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTQKNSKLCSRANVYTQVPDGGWGWVVAASFFFIEVFTYGVIKSFGVFFNDLMDSFDESNSKISWIISICVFIMTFTAPLSTILTNRFGHRLVVMGGGLLISVGMIAASFSQRVYQMYISIGIVSGLGYCFSFLPTVTILSQYFDKRRSMVTAVASTGECFAMFAFAPAITALKEHIGWRYSLLFVGLLQLNVMVCGALLRPIIIKGPGSPKAIPLEPRREVQYMLENEKTRTSIDSIDSGVELTTSPKNVPSEAKREQEVRVEQQQTLVVGPKHSQKRAPLLDFSILKDRSFICYTLFGLFATLGFFAPSLYIIPLGISLGIHPDRAAFLLSTMAIAEVFGRIGMGLVLNREPIRKIYIELICVILLTVSLFAFTFATEFWGLMLCSVFFGSMVGTIGGTHIPLLAEDDVVGIEKMSSAAGVYVFIQSISGLAGPPLAGLLVDQSKIYSRAFYSCAAGMALAAVCLALVRPCKKGLCQNPHSGENQTDGHRGKALQDIPEDFLEMDLGKCEPRAHMKMDPV", "length": 522 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q7TN50-1", "protein_name": "Mas-related G protein-coupled receptor member B8", "gene_name": "Mrgprb8", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDSSIPDPEADLIQLNGSYHTETSPCVIESRVMILLSIIIAFFGLAGNAMVLWLLAFRMRRNVFSVYILNLAGANFLFLCTHTAFSLEKIIVLFHSVHIHIPLLFYTLSTLAYLAGVSMVTAISAEYWLSGIWPYWYQGQRLKHTTTVICTGLWGLALLLSLLEGKSCGFLGSTYNQDVCWKLDFIIVAWLLVLFAVLSRSIQVLLVRIFCGSQRTPVTKLHVTIVLTALVLVICGFPFGIIFYLLYWTTEVYYIMPCNSFHETILLLSYINSCANPIICLLVGSIRHCRFQCGTLRLLLHRAMQDIPEEEGEELEEVVGERVQNSIP", "length": 328 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q7TPX8-1", "protein_name": "Oogenesin-2", "gene_name": "Oog2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNFYSPPTLMELARQCLLRDEYLAISALKDLPNMMFPVMFKEAFIDGHTKILTAMIPVWPFPYLSVGTMLKNLNLDTLKAVLEEIDILISKPVFSSRCKLREITLSHDLVVVWAGSHEVEGLPEFMEQEKPVENSPGYGTKNKLKVTTELQFMEGHLDECSTYLLQWAYQREDSIHLHCRKLKIYGLTKAAVIEMFKIVHAEYIEDLELSCLCLEYLDFLNPYLKQMSNLLSLTLDEIIYTLNIDDYRNLNEEKVITVISHLPTFHHLQELYVHGVIFIECLRCLKKPLEVLSFTDCDLSQSDLDYLPYCLNIFELRSLHLTDVRLSNLLLEPLGFLLERVRHTLKSLQLMSCEMGETHFNALLPALSQCYQLTVVNFYGNELSLLFLKKLLHHTAKLSQLADELYPAPQECYDNRDVVLSHRLENFCSELLDILRAIREPKKVTFGTIKCSKCGGSYVYDLETQCCFFEKNPPWA", "length": 476 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q7TQY5-1", "protein_name": "Olfactory receptor", "gene_name": "Or4k38", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEDSNRTVSSEFIFQGLCSSRQLEIFLLLPFSILYLMAVVGNLFVVILIIIDHHLHSPMYFLLANLSFIDFCLSSVTTPKLTIDLLKENKTISFVGYMRQIVCVHFFAGGEMVLLVTMAYDRYVAICRPLHYSSIMDRQKCIWLVVISWIVGFVHAISQMLLILDLPFCGPRVIDSFFCDIPLVMKLACMNTDTLEILINADSGILATTCFILLLISYTYILLTVQHRSKDGSSKALSTCTSHIIVVLLFFGPIIFIYLWPVSITWVDKFLAVFYSVITPLLNPAIYTLRNKDIKNAIKKLISHK", "length": 305 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q7TR72-1", "protein_name": "Olfactory receptor", "gene_name": "Or8k25", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEKYNLTIVTEFILVGITNHHEFQVPLFGLYLIIYLTSLVDNLGMIILTIVDSRLQTPMYFFLRHLATTDLGYSTAVGPKMLRNFLVDQNIISFYACAIQSSFFGMFIVCEFFILSAMSYDRYVAICKPLLYTVIMSQKACWILVTIPYLYSIIVSLLVNIKIFTLSFCGYNVISHFYCDALPLLTLACSNTHEIEAIILIFSAFNLLSSLLIVIGSYLLILMAILRINSAEGKWKAFSTCGSHLTVVIVFYGTLIFMYLQPTFTHSIDTGKVISIFYTQVIPMLNPLTYSLRNKDVKDVLKKPMEKVHNLFS", "length": 313 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q7TSF0-1", "protein_name": "Desmoglein-1-gamma", "gene_name": "Dsg1c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDWHSFRIAALLLTSLVVLEVNSEFQIQVRDHNAKNGTIKWHSIRRQKREWIKFAAACREGEDNSKRNPIAKIHSDCAANQPVTYRISGVGIDQPPYGIFIINQKTGEINITSIVDREVTPFFIIYCRALNAQGQDLENPLELRVRVMDINDNPPVFSMTTFLGQIEENSNANTLVMKLNATDADEPNNLNSMIAFKIIRQEPSDSPMFTINRKTGEIRTMNNFLDREQYSQYSLVVRGSDRDGGADGMSAESECSITILDVNDNIPYLEQSSYDITIEENTLHSQLLQIRVIDLDEEFSDNWKAIIFFISGNEGNWFEIEMNERTNVGTLKVVKPLDYEAVKNLQLCIGVRNVAEFHQSIISQYRLTVTLITVTVLNVVKGCVFQPGSKTFIVDSRMEANHTVGEFLATDCETGQATNKFKNVRYRYVMGNNPENLLVVDSGIITLRNRVTMEQYERLNKRYEGTVLSIHDSLQRTCTGTIIMVLCGFWTTTEHPTTSTEKPVTLSITPNVDNVHFGPAGIGLLIMGFLVLGLVPFLLISCDCGGAPGGGAGFEPVPECSDGAIHTWAVEGPQPGGITTICVPQMPPGNANVIEYIDNSGVYTNEYCGREMQDLGGGERTTGFELMDGVKTSAAPEICQEYSGTLRRNSMRECRDGGLNMNFMESYFCQKAYAYADEDEGRPSNDCLLIYDIEGVGSPAGSVGCCSFIEDLDESFLDTLGPKFKKLADISLGKEIDSYPDPDPSWPPQSTEPICPQHMEQLASGHPSISPHFGKTTVISENAYPSGPGVQHPMLIPDPLGYGNITVRESYTTSGTLKPSVHFHDNQQASNVVVTERVVGPISGADLHGMLEIPALRDGTNVIVTERVIAPGSSLPNSLTIPNPRETSNVVVTERVIQPTSGMIGNLSIPP", "length": 911 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q803M0-1", "protein_name": "Protein phosphatase 1 regulatory subunit 3B", "gene_name": "ppp1r3b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MPIELAMSLYLSSDEFLNPRASKYSRPLQPCLNQCKSSKLSFSSLKEQSEFNGVSRALMIPGRAKKHVSFADHKGLALTVVKIFSEFDDPIDIPDNIDNFFTSSLTVSEGKDKLTLDFDQPSADYLKFRQRIENDHVCLEHCMLKEKSIMGTVKVKNISFEKSVKLRITFNTWKNHTDVECQYVKDTYTGSNRDTFSFEASLPEQVPSHERIEFAICYEVNGDTLWDNNQGKNYRIIQSALRKSSNESNGGHQQYSQSDWDIHFDRYGSPRCSRGIFPHWPSYVGYEDIGPYY", "length": 293 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q80SW5-1", "protein_name": "Embryonic testis differentiation protein", "gene_name": "Etd", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDEKNPEAVPRPPEQNTELVPPKKSKSKKPANILIYLIDRHLGRPRNDMDLFEWVWTLK", "length": 59 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q80VJ6-1", "protein_name": "Zinc finger and SCAN domain containing protein 4C", "gene_name": "Zscan4c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASQQAPAKDLQTNNLEFTPTDSSGVQWAEDISNSPSAQLNFSPSNNGCWATQELQSLWKMFNSWLQPEKQTKEQMISQLVLEQFLLTGHCKDKYALTEKWKASGSDMRRFMESLTDECLKPPVMVHVSMQGQEALFSENMPLKEVIKLLKQQQSATRPTPDNEQMPVDTTQDRLLATGQENSENECNNSCNATEANVGESCSGNEMDSLLIIQKEQHPEHEEGNVVCQFPHGARRASQGTPSHHVDFPSAPTTADVPMEEQPKDLSRENISEDKNNCYNTSRNAATQVYSGDNIPRNKSDSLFINKRIYHPEPEVGDIPYGVPQDSTRASQGTSTCLQESLGECFSENDPREVPGLQSRQEQPISDPVLLGKNHEANLPCESHQKRFCRDAKLYKCEECSRMFKHARSLSSHQRTHLNKKSELLCVTCQKMFKRVSDRRTHEIIHMPEKPFKCSTCEKSFSHKTNLKSHEMIHTGEMPYVCSLCSRRFRQSSTYHRHLRNYHRSD", "length": 506 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q80VT8-1", "protein_name": "S100 calcium-binding protein, ventral prostate", "gene_name": "S100vp", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAQNLTSTEQEIMELLMILQEFSVKKIDKLDVQEVKRLFREELPNFLKAMDEATKNKILNDKGKEMPFDEIWDMIGRMALEYRKKNSNALKD", "length": 92 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q80XZ1-1", "protein_name": "Polypyrimidine tract-binding protein", "gene_name": "Smptb", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSRNSPPAAEGNGSKRFKGDSWGTRDPSRLVHILRLPSCVTEGEILCLALPFGEVSNLLFLRAKNQAFVEMSTEESANTMINYYTWMPPVLRGQPVHIQFAHYRELKVSSSPSQEISLSQAGDSREATASSLVAVPGQAAASGQTAVPSQLGAQPCLPPEDSYQAGTVALAPPASAVDTELVVAWQSPVLRILVENYFYRVTLEVLHQIFSRFGTVLKIITCTKNNRFQALLQYAHVMSAERAKLFLDGQNIYDACCTLRISFSGLTNLMVKYNNDKSRDYMRPDLPSDDSQPSPVQVQNMASALPAPAMSSASPYASIALPHTFAIPQAAGLANPEVFKTLHPQAIQEVAMASSSSSSSTAAAAVGAAEIAAAAVPGAEGSMVTSGSPGVGSPVLLVANLNQEKVTPRSLFILFGAYGDVHRVKILFNRKENALVQMADGSQAELALRHLNGHKLYGKALCILLSKHQSVKLPREGKEDQGLTKDYANSPLHRFKKPGSKNFQNIFPPSATLHLSNLPSLVSEEELKNLFSSNGYAVKAFRFFPKNHKMALIRMGSTEEAIQALVDLHGHLLGQNHHMRVSFSRMTI", "length": 588 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q810J1-1", "protein_name": "Pregnancy-specific glycoprotein 22", "gene_name": "Psg22", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEVSSELLSNGWTSWQRVLLTASLLTCWLLPITAGVTIESVPPKLVEGENVLLRVDNLPENLRVFVWYRGVTDMSLGIALYSLDYSTSVTGPKHSGRETLYRNGSLWIQNVTREDTGYYTLQTISKNGKVVSNTSIFLQVNSSLFICGRPSPPALLTIESVPASVAEGGSVLLLVHSLPDNLQSLLWYKGLTVFNKVEIARHRTVKNSSEMGPAYSGREIVYSNGSLLLQNVTWEDTGFYTLQIVNRYWKMELAHIYLQVDTSLSSCCDDFNSVQLRINPVPPHAAEGERVLLQVHNLPEDVQTFLWYKGVYSTQSFKITEYSIVTESLINGYAHSGREILFINGSLLLQDVTEKDSGFYTLVTIDSNVKVETAHVQVNVNKLVTQPVMRVTDSTVRIQGSVVFTCFSDNTGVSIRWLFNNQNLQLTERMTLSPSKCQLRIHTVRKEDAGEYQCEAFNPVSSKTSLPVRLTVMNE", "length": 475 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q863C3-1", "protein_name": "Gastrin-releasing peptide", "gene_name": "GRP", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MRGREVPLVLLALVLCLAPRGWAAPVTAGRGGALAKMYTRGNHWAVGHLMGKKSVAESPQLHEEESLKEQLREYAQWEEATRNLLSLLQAKGARGHQMPPWEPLSIHQPAWDSEDVSNFKDTGPQHEGRNPQLN", "length": 134 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q869X2-1", "protein_name": "Probable polyketide synthase 17", "gene_name": "pks17", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MTFNNIKDENNDDIAIIGMGFRFPGGGNNPYQFWNQLSNKMDGISKIPTEKWSRSFYEQKYINNEYGGVLKDEEWKNFDPLFFGISPKEAPIIDPQQRLLMTTLWEAFEDANIKPSTFRGSDTAVFIGMMNTDYQRCQFRDISYVNPYITPGTAGSFISNRLSFSFDLRGPSMTLDTACSSSLNAVYLGCQAIANGDSKMAIVGGVNGIFDPCFSMTFSGLNMLGHKGQCRSFDAGADGYIRSEGGGVCILKKYSDAIKDGDRIYCVIKGGSSNVDGYNAKTNIIQPSMKAQGENIEIALKKSGVNPSDIYYIEAHGTGTPVGDPIEIEAISRIFKDNHTPDAPLYIGSVKSNIGHLESAAGIASLIKVALSLKNRSLVPNIHFEKPNPLIKFEDWNIRVVTDEIQFPINKLINMGINCFGLSGSNCHMILSEAPINYDELLKTTNNNSTSSSSNDDKKEYLIPFSANCNISLDKYIEKLISNQSIYKDTILFKDFVKHQTISKSNLIKRKVITASDWDDFLNKRNETTSTSSLTSTISAPASSTPVIYVFTGQGPQWRDMGKALYETESVFKDAIDHCDKLLANYFGYSILQKLLSLESEDSPEIHHPILAQPSIFLIQVGLVALYKSFGISPSIVVGHSFGEIPSALFSDVISLETAVKIVYYRGLAQNLTMGTGRLLSIGIGADAYLEKCALLYPEIEIACYNDPNSIVITGSEQDLLGAKSTLSAEGVFCAFLGTPCSFHSSKQEMIKEKIFKDLSDLPESNVPCVPFFSTITGSQLSHKGFYNVQYIYDNLRMPVEFTKAISNIFNFIEENESYKNAIFLEIGPHPTLGFYIPKCKPSNSTITSKPIIVSPLHKKKEELTQFKLAISTLYCNGVEIDFASGQQLLPTSSSSGGGDISSFKESTNKLPRYQWDFEEYWDEPNQSKMVKRGPSNNLLGHDQFAGNTLMELFIDIDKSAHQYLKGHKIKGKYLFPGSGYIDNILRQFNGQDITIFNLEFSNPFFLKDGVQHHLQTSITPTTKGEFKVEFFIKDNRNSTKWTKTSNGRIGLFKHNPKNNKLDIEKLKSQCSFTTLTKSEVYNKLLLLSLPYGPTFQRVESCSIGDGCSFFKLSMSPCSEFDKDFLNPSIIDCAFHGLLVLSEGPQEIVFDRLQDMKFYSSNVPSTRPQFIYAFAKFDKIEGNSTHGSLNIILEDGTLLISIKNVKCTSLIRLKKQSIKYPSQNVYSHHWQSKDSPLTLIENQLIEEKSSESKINFEKLLNDKLFNYYLIRLLNQSIKSEFIEFDYKTSTVDTLDIGSKNAKLLEKIQSILNPIDSLDQSIDITSLKQAIIVKSSFKNEIKLVEKSIKRIVSLLKGGESEHFSPSNPSSPNDTPRNNSNNCSSKNNAASSDDADDDTNNEETINQLNNEPFNFSNSQFISNQNQLISKTIVNSFDRLINSIEIGEKKLIKIIDLSSIYQNYQLSKLLLLQLNQLLINLSNNNNIEIEYTIPSNTKNIDSITEETKSISNVLNIKYRSFDLQDDLESNGYLNSNYDLIITSLLLVSTNSIDSNEVLSKLYKLLLPKGQLILMEPPKGVLSFNLLFANDFKQSLEIKSEQEIKSLIIYCGFTKIETNLNTKDDEEQQQPPPPSILIVQAEKRDIESMSLTFSSDPKSLNSSYSNCIFIVSKEQKENPTSYIQEYFDITEFFCQNATIIEADDSELLTKTIESGVGKNDIIFFLVSLEELTIENYKQVTMQYTLVNQILLRNNLSTRFALLTYDSQNGGKNYLGSSLIGTFRYFLEFRSLNIFSIDVDKDSIDNLTLFLRLVDLSTIGDRETIVRNNKIFVQKIFKEPKLLSPSNNYEKNTNNLFLYSNSNLDFSFQSKEKLLHGCVEIKVMSTGINYKDSLFYRGLLPQEVFSKGDIYSPPFGLECAGYITRVAPSGVTRFKVGDQVVGFASHSLSSHVTTHQNKIVLKPENISFNEAAAVCVVYATSYYSIFHIGAFIADKESILVHSATGGVGLASLNLLKWKRNQLKKHGNSEISNDASIYATVGSKEKIDYLQEKYGDLITAIYNSRDTEYCDEIKQQSAQGGVDLILNTLSGDYLSSNFRSLSQVGRIMDLSVTQLVENDSLDFSNFKYHVGYNTIDLDRATKYNSKIIRDILTEVFDAISDGSLENIPVKVFPAIQVKTAIEYINERVHIGKIVVDFENFEQDILKPALQEKENPIQLNKVKKLEHTCDTLNNTILITGQTGIAVHILKWIISGSVLNSNKSQQQVTDFIILSRSSLKWELENLINQTKHKYGDRFRFHYKSVNIADLNSTRTAIDQVYSSCKNVSPIKSVLHFATVYEYILPENITQTVIDNTHNPKAVGAINLHNLSIEKDWKLENFILFSSIGAIIGGSKQCAYSSANLVLDSLSNYRKSIGLASTSINWGGLDAGGVAATDKSVASFLEGQGILLVSLSKILGCLDSVFQPSNSHLSNFMLSSFNIDNLLSSAPQMKRKMDHHLTNYKTSSASSDDSLGDSGSTQAKVISTISELLSIHPSKLNLDTRLKDYGIDSLLTVQLKNWIDKEFTKNLFTHLQLSSSSINSIIQRISSKSTSTSTPNPTNTSKQTATKKT", "length": 2604 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q869Z5-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSHLTPKPNVLNVYGAGTPNFVKVQILLEEKNIPHVYHKIDFSKNEQFDPEFLKFSPNNKIPAIVDNTVEPNGISVFESAAILMYLSEKHQFTDLYADFKTDPALHAKHLEFLFFQMSGVGPMTGQLGWFLRQPEPKNTQAIERYSEEVKRLYRVLDKILSTNTWVAGEQYSIADISLLGWALYFLKGYYDDHITREQFPNVYRWLDLAAKRPAIIKVLETIQPKQK", "length": 227 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q86AE3-1", "protein_name": "Probable polyketide synthase 9/36", "gene_name": "pks9", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MGNLKNINLKEKGVAIVGIGFRIPSGNNENSISSPDDLFNNLKNGFDGVSSTSERWSDNFHKLGEISSPNAGLLPFKEWKSFDPLFFGINPSEAPLIDPQQRLLLKCTWEALEDASIDPISIRGTNTSVFIGSSTIDYLHTNKHQDSVLKNAIAQSTSAISNRISYCFDFNGPSLSIDTACSSSLNAVSQGYHSILNGTSNMSIVGGVNLILDVDIIKAYSILSMLSKTHGKCKTFDESGDGFTRGECVGVVVLKNLQDAVKDGNRIYCVINGSSSNVDGNGNMDKVNFYSPSKQSQFNNINSAFKSTNDKLSINDIQYIEAHGTGTKTGDPIETEAISMAFKNRDKSTPILIGSIKSNIGHCEAGSGVASLIKCCLMFKYQCFLPNIHFKNPNPLIKFNEWNLKVVTSPIPFNKRNNEKPVSMMINNFGVTGSNCCLLISEFKNNNNFKENINLESQSVNDRVLIPFSANSSNSLNQYQSKFKNIINNQFNFIDFTANQIYSKSNFLYQRSVVIASNSNELFENISNKKQIQTKNSIISNMSFKGKNPITIFVFSGQGSQYPKMALELYNNEVIFKKSIDLIDSKLSKYYGFSVWEKVKTIKDDDLTSIHDPIFAQPALCMISVSLFELYYHWGVNPSFILGHSLGEISASYCSGMIDLDTFCYTVYQRSIAQSKTNGCGRMLSINISDEEFKSMYSQKYPQIEIACYNSPQSIVVAGNESILNEISKELKEKEIFTTMLGSLSSFHTSSQQCTKDSILQLNIESNQPKVPIFSTVTTNLFNESNRFNSQYVYDNIIKPVKFTQTISNIYKHIESNQLNNEIVFIEIAPHPTLLFYIKQMVPSSLNESVSVYSALHKKKNDVEEFQQTISNLYCQNGYNINFKCQFNNKKSNQSINLPLYQWDEELYFTQAQTLEQHRKEGPPIDHLGTSNSYNSPFNNSYRTSIDIKNKPFLYLKGHMVKGKYYFPGCGYIDNIIQLYKNQDIFISFIEFKTPLILIEGINQYLQTNIQQTGKSEYRAQFHFKDQKSNEWIQSSNANFQLLDHGNDIPPKYNIKEIIENKCNLSKLTKNELYTHIKSKTGLNYTGVFQGVTECYIGGDCTLSVVSLESQTNSFLNIPILDTCLHGMIGLSNDQCQIVFDKAIGFKYYSSNIPANLKDYKDSVYVYSHLKSKSVDSFFGSIIVMLSDGSVLYEIEEVVCKSLIPIKDSLKIEYPNDELYKVHLQSKDSPIPTPSSFKSIIYENDFFHSALNIPEDLFKYISTLFYKDIIKRCPEININKINSHSVNEIISSFSKISKHERLFRFVFETIKENGILNSLEENDDAYFEFNEVIIKSSRIISKLLFPLESDNDNEDLPQSLFQNGLMDKIYKCRYLRKKNQMISHVIKHSIKEIINNNIIIRILEFGGGTASLSVEVIEEIIALLQENPNYQVEIEYTWSDISPAFIADAKNKINKIINDAAITNGFNVIYRPLKIDESLIETQSINPSYYDFVIMSNVLHVVKNIKQAVEQMYQLLTPNGQLLFLEPPYKSVLNDSIVGSFEQWWSFTDTDIRKDRCSMSQQSWCQLLKTCNFKDIAMSKECIFVGIVIHAQKPPISLLNSQPKRDNIIIYGGGNPIFVENIKLYSNSKSLIQIETIQEFNQLLSQSTITNDSIIYFIKTLETLSLDNFKQITLEYIEINRKLLQINSLCKHVLIVSDSRKTNYLASSVVGAARYFDEFQQLKLNTLDFDYDSTQNYINSNNKDMVQFINILTDSKTNVHKEMIIINNKVYYEIVQKEKNLKLKYNSESFENQNNLMCSLSPNLEYQLQSKQIKLRDNQVEVKTIATGINYKDYLNFSGSNSNGDDNTGLPQFGYEFSGIITRVGNNVKDYKVGDNVFGLSNSCTSSHIVTNYKKIQIKPSNLSHNEASSIPIDYLTSFMSLFNIGSLNIEDNESILIHLGSDGFGLSTFEILKWKGFNSNLFVTVNSYETKRYLQDNYGDFITGIYSNTDKSYVTEINKKLIKLGSKKKGVDLILNTLPSDFMDSNFKLLAKYGRIIDLTSNHLNQSEFLKNINFKYNHGYHNFELSLIQKNKIHKCLYEISNAFENGELKTIPIKEFTNLNIKDAIKYITNNKIEKITVSHDHEIYSDIIYRSLDEKEFSILKSNYQINSNNLGKNILVTGQSGIILEILKWIIKYSNINTIENVIILSRSSLKWELELLINETKLSNNNIKFHFKSVDIGDSEQVDNAINEILNENQQITNIDSIYHFAFQQITCKVQEINMKHLDISHGAKSMGAINLHNQSIKRNWKLINFVMASSAISLIGSTDLCTYVCANALLDSFSKYRESLGLPSTCICLGAIESTGFVSKNESVSVFLDGGGFHPTPINQVLGLLDLQIQNAGKFTNSMLSNFKPSKFKNNQQTSLFLKFDYLMNLKNNSEETKIENTGNKNIDELFIEKVSELFSMDESKINKNLRLIDYGADSLIIVQLKNWIDKEIGINLITIQQLQNNTISTSMKMILNSLMKNNQNIDDNNKDLPSNRIDYWKNEMKFEESIKPISNEIQSRNNSEKIILLTGTTGFLGGFLLFNMVRLDSCKLIYCLIRNKSKSNNPLDEIINNLKYHQLYEKLNQSQISKIIPIIGDLSMNKLGLSNDDYETISKNVNLIINPGADINQKSSYQDCKLVNVNGVKEIIKLSLSSLKQRIPIVNFSSFSVFFNQSLDKNFDESVLPSIDNIDNLPTEYMKSKVVGEYILLEASKKYNIPSILIRPPSIFLNPETGIGHISDFSLLSIQSCYELGYYPNQFENDFILINTITWLSNNITNIIMNDNCWTDSKMNIYNVHGKQIQSSLIIKPLEKHFNCKHINTNDWIDMVNNSNKKSCIKLKSFHSLDIILKSENNRYKPNENQSISLSTKSLLESMGSYNTDLEITDKMIISHINQIFNLNETI", "length": 2931 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q86AF8-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MFSKFSIKENKPKKVKSNSSKGFNNNEINSTNNNNNNNNNNNNNNNDSDNFINNNDSNNNNNFNNNNNNNSNNINNKTEDSNDISLLINQFIGSSPAPSTCSGSDKFSIKPKKIVTPSKRKNSTSGSDIIDFNNCNNNNNSKSNSDSNNNKYNNSNSNNNSCNNTNNGNERKMKGYDYGNNNSNNNYSSSSRDYNSNNNSSPRDYNNNNNNNNNNNNNNNNNSNNNSPRDYNNSRDYNNNNTNNNSSPRDSNSNNNRNSSSRDFSNNNSSPRDYNNSRNSNNSFLNNNNNNNNNSNNSNDNSPRDYNYSSSNSSPRDYNNNNDTFSKKRNNVGNSILEIKSNPTSPRIKPIMVWPRSSPRIVNKLPPVQSLVDLTEIEMIDDNNNNNNNNNNNNNNNNNNNNNNNSNNNNNKSGSNNNFSDSDSDKDNYNNNNNTNNNSFNSDSDNYNNSNNNNSNSNSNSNSNSNSNSNNNNNNNNNSNNNNNNNNNNNSNNSNKSNNNFSNIKILEKRRKSINEISDNLTTRNIEEIDSKMAHEFEHPFLEKLIFAGQRPPFVECDDYFLKRYKNQFQYYLDISMKSIINTRDIGEGDDDDEINSVPFKCTLCSYEYDEENNNENTNGFIDEADKIYNRSNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSNSNNNNNNNFYDKKYFKNNYFQHLLSKHLNQIKAKGIQDTNVYNDEANIPLGSKKCDHLECSEIILKNEFTKHIKKLHHHHKDEDIDICPRCKILKKSIQKRIVKFSKKKQEKDDDNNSKPVSNKVATISHNPSPNNIDKDINNNNNNKNNKNNTNNLENDNNDNSSNNNYLENEEEPEIVFQDIKPNNNNNNNNNNNNNDDNNNDNNDNNDNENNNDNNNDNENSNNNNNNS", "length": 901 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q86BK9-1", "protein_name": "Mediator of RNA polymerase II transcription subunit 22", "gene_name": "Dmel\\CG32971", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSDSKDEALLKSFKTQLKDNVLSMLLNFEELLKLVSPRTPGQITNDTEQELNAFEMQVRAGNFVRAGEALIKLVHDVKEYQIIYDYSNIEEEMDRQSEAMHAKVTEYDQTLIKMVKDLEEELSELEYEYYEKSGGPDLDSKDLLV", "length": 145 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q86IJ5-1", "protein_name": "Uncharacterized protein DDB_G0272718", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MPPHGHHHHHHGHHGHHEHITITPVYAPPQVVQPIYAPPPVVQPVYVQPPVVYPQATIVLETGHHHGHHHHHGHHGHHDHHHHGHHGHH", "length": 89 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q86IV6-1", "protein_name": "DNA replication ATP-dependent helicase/nuclease DNA2", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNFFEKKNNNNNNSSNNNNNNNNNKNNNNKNLDKNNSSDRNNNNNGDKNNLKPTQKSLIDLWFQVDDEDEEYELSSLSNDGGSSFNSFKVNNRDTSIGSDIYSKTITPSSLALSTSSLISSTLTPPTQSPPFSKKNEKTSSFLNSPSSQKSKSNNSNVKEKLSPQYSSSSQLSDFFKKKKRPLLDNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTISSLNTNSNNNSSGSSNGSSSSSSGGGNKSSNNKKQKVSQSTSSTSLKEKQSQQSILSYLNPTPSLPTPIFDKPIERSDSNLATSSFSKLNFDDIPLDDEELSQKINTPSPKLILKNTFSSTPTQKSPSLSSTPPNKIKITDKKLPNSSSSSSSPPPSSAKSKLSHRSQSSPLSPLITNLNQNKSNEFDDINFNFNIPSPLKEINNKPNIKSNSKETLTPLTQIFHSSSPPPSIIIESSPSVCFSPTPTKNQSPTLSNLSPTFSFLSDTSPVKSPSQLFEFTFDDPLSPKLISSNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTNTFISKNNLINLFNEQSNQENVSTTTTTTTTTTTSTSTNNNNNNRYERVLIINVFYEVTQIFNNSNDKIHKKTLSGFSESIGESREIQLLDEWIYTPVRPGDIVNVIGEFDDNGEIIINNIQNLLILHPDILITGTELGGSLTCTRRSVLKEQIRVGNSNSSTVPIFGSIVHEIFQECLKNNRFHLDDINTFKQEIIGKSTFQLGLSSLGETQDTALNHLENWLPTIDKFAKTFILPSSSSSSASSLKKNLIEINSEKWHLSISKILEIEENIWSLMYGLKGKIDSSLEIKLVKQQQDEKQSKQSKQSKKKKQQTTSPNNNNNNNNNNNNNNNNNNNNNNNNNNGPTTCYLNVPFEIKTGKPYQIPYISHSSQVLIYTLLMNDRYDQDIEMGILYYLKSQEFKSVGLNYGLLHPILFERNQIRSLIVSRNLLAYFLNLNSQPLLKPNPILPEMLRDYHSCTKCYSIDPCVLYHKAIENGDQFTSSLGDLFLEKTNHLSSIHINYLKNWNKIISLEYSIKNNKRKLIWNKSRKFGEKNNSCIGELILISEEYSEITETFSYRFRVNPDKLLNSSISEGDYLLISVEDKYYGMGSGQLSNIINDIITITCREKLSEPPSLLSDYTTPNCNNNDPSYFGNYRNKPLIYIEYEDADQQQQQQQQQQQQQQQQQQQQQQQSQKQQKQKQPNFTQLRGLNNYVNNSKLTPFKWRVDIDEQLSGLSIVKSNLFNLFLKENQKLRSLIVDLEAPIFDKLEQENYWKSIDFQNDYPLLNIDQRNAIIKTLSAKDYSLIHGMPGTGKTTLVISLIHILWRLGKKVLITSFTHTSLDHLLLKFNKQYPNIEMLRVASSLNQIDPSLHRFTLEKQSFGNITQSKQYLERQQLVATSCLGINHQCLLKMQFDYCIIDEASILSQPISMGPILKCKSFVLVGDHHQLPPIVNNKEAGKLGLDISLFKQLSTSHPSSVSNLYHQYRMCNSIMSLSNHLIYNNRLVCGNQSISNLSLQTNYYHNNNNTTHIDLLDHINNWPQIICNPNSSVIFVNTDQLNNSTESSNGDLFYNQTEANIVAILTNCLINKLNINQSQIGIITPIRFQLNFIKKSILKYLSIENNNNNNNNNNNSNNNNNNSNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNQNNNQNYLKKIENLDILTIDKFQGKDKDCIIISFVRSNEKKEIGELIKDWKRMNVAFTRAKKKLIFVGSKSSLSKFPFFLDFFEFLDSKNWIYNLNNKIQF", "length": 1838 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q86JI5-1", "protein_name": "Probable polyketide synthase 5", "gene_name": "pks5", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MDMKLNDIENENFINQMKGVAIVGIGFRIPSGNSENSISSPDDLFNNLKNGFDGVSSTSERWSDNYHKLGEISSPNAGLLPLNEWKSFDPLFFGINPSDAHHIDPQQRLLLKCTWEALEDASIDPISIRGTNTSVFIGSSTIDYLHANKHPDLILKNAIGFSPSTLSNRISYCFDIHGPSLSIDTACSSSMNAVTQGYHSILNGTSNMSIVGGVNFVIDVETIKGFSYLNMLSKTHGKCKAFDESGDGFTRGECAGVVVLKKLDDAIRDGNRIYCIINGISSNIDGNGIADKANFYSPSKQSQFNNINLAFKSTNGKISVNDIQYIEAHGTGTKTGDPIETEAISMAFKNRDKSTPILIGSIKSNIGHCEAGSGVVSLIKCCLMFKYQCFLPNIHFKNPNPLIKFNEWNLKVVTSPIPFNRNNEKSVSMMINNFGVTGSNCCLLISEFKKQDYESYENNIGSINKNILVPFSANSPKSLDQYQSKIKNIINNQFNFIDFANNQIYSKSNYLYQRSVVIANNSNDLVNKILNKKHIQTKNPIISNMSFKGKNPITIFVFSGQGSQYPKMALELYNNEVIFKKSIDLIDSKLSKYYGYSVLEKLRSIGDDDTTSIHDPTIAQPAMCMFSVSLFELYKHWGVNPSFILGHSLGEIPTSYCSGMIDLDTFCYTVYQRSIAQTKTHGNGRMLSINISDEEFKSMYSQKYPQIEIACYNSPQSIVVAGNESILNEISKELKEKEIFTAMLGSLSSFHTSSQQCTKDSILQLNIESKKSKVPTFSTVTTNLFNESDPFNSQYVYDNIINPVKFTQTISNIYKHIESNQLDNDIVFIEIAPHPTLSFYIKQMVPSSLNESVSVYSALHKKKNDVEEFQQTISNLYCQNGYNINFKCQFNNKKSNQKINLPLYQWDDELYFAQTQVLEQHRKEGPPIDHLGLSNSYYSPFKNSYRTFIDIKNKPFQYLKGHMVKGKYYFPGCGYIDNIIQLYKNQDIFISFIEFKTPLILIEGINQCLQTNIQQTGKSEYRAQFHFKDQKSNEWIQSSNANFQLLDHTIEMPPKYNIEEIIKNKCTLARLTKNEIYTHIKSKTGLNYTAMFQGATECYIGVDCTLSVVSIESQTNSFLNIPILDSVFHGNISLINDQCQIVFDKVHGLKYYSSNIPNDYKDKSVYVYAKLKSKTSDSYSASFTVLLSDGTVVYEIDEAFSKSLIPIKELLKIEYPNDELFSINLQPKDSPIPAPSTFKSLIYENDRFNAEPPMVENLFQYISTIFYKNIINRCPEINIDIIKSLSIDEIISNFSKISKHERLFKYVFETIKENGILNSLEEKDDTYFVFNEVLIKSSRVISKLLFPLENDNDNEDTPQLLFQNGLMDKVYKCRYLKNKNQMIAHIIKHSIKEIINNNIIIRILEFGGGTASLSVEVIEEIVTLLQENPNYQVEIEYTWSDISPAFIVDTKNKINKIIKGAGITNGLNVIYHPLTIDESLVELQSIKPSYYDFVIMSNVLHVVKDIKQAVEQMYQLLIPNGQLLFVEPPYKSIICDSLFGSFEQWWAFTDTDIRKDHCCLSQDGWYKLLKWSNFESIEMSTESKFMGSVIQAQKPSFTSLINQQPKYDNIIIFGNNCPNFIDNIKPFSNFNEFIQIETIQEFDQLINKSTITNDSIIYFIKSINQLSLDNYKQATLEYIEINQKLLQINSLCKHVLIVNDSRKTNYLASSIVGAARYFDEFQQLKLHTLDFDYDSTQNYLISKNNKMVQFINNLIDSKTNVHKEMIIINNKVYYEIVQKEKNLKLKYNSESFEQQDNLMCSLSPNLEYQLQSKQIKLRDNQVEVKTIATGINNKDYLVYSGLEGSVNSNTPQFGYEFSGIITRVGNNVKDYKVGDNVFGLSNSCTSSNIIVNHERIQIKPSNISHIEAASIPIDYLTSFMSLFNVGCLNIEDNESILIHLGSDSFGLSTFEILKWKGFKSNLFVTVNSDEIKQYLLNNYGDLITAIYSNTDKGYVSQIKNKLIEQGSNDNGVDLILNTLPSDFMDSNFQLLAINGRIIDLSNDHLNQSEYMKNVNFTLNRGYHNFDLMSQRNSRINRSLLTISKAIENGELKLIPIKEFSNSDINDAIEFIIEENRIDKIVVSHDHEVYQELYAKFSNENDFSILKSNYQINSNNLGKNILITGQSGIILEILKWIIKYSNINTIENVIILSRSSLKWELELLINQTKLSNNNIKFHFKSVDVGDSEQVDNAINEILNENQEIINIHSIFHFAFTQIACKVQEINMKHLDISHGAKTMGAINLHNQSIKRNWKLINFVISSSIASLVGSTDQCSYVCANALLDSFSKYRVSLGLPSTSINLGAIESTGFVSKNESISVFLDGSGIIPTPINQVLGLLDLQIQNPGKFTNSMVAKFNPLNFSNNEQINLLLKMDYIFNLHSNGYTKVKESAGSKNVDELFIKKISDLFSIDESKINKDIRLIDYGADSLVIVQLKNWVDQEIGFNLITIQQLQNNTINVSIKIILNFLKKINK", "length": 2512 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q86KS1-1", "protein_name": "DNA cross-link repair 1 protein", "gene_name": "dclre1", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSDDEDDINLYITRSKNNENKKTNKNRLIDNNIQKTKTTTAVLTTRTTTTTTTTTASTQLKWDYGDEDDDDYSAPKDIDEEQSSKQFNYQNNQIVVKQDHDDYSAPKDMDEEQSSRQFNYQNDQTLVKQDDDHDDYNEPKDIDSQSLIDEDCDFEFDNSDFFFDDGTTNNNDNNNKNNKNNNNNNNNNNNNNNYNNNNNKNYKRKYYQSYNNSNNINNNNNNNNDKFEKRLSDLKKTGKEEAKKRGYQVRKTPTKEKKIPPSFKVIDGTNFLVDGFQYKSEDFTHYFLTHFHSDHYVGITKTWSFGNIYCTEETGKLVSHKLGVDQRYIVKCEWNKLIEIQGVKVAFLDSNHCPGSALILFIIPLRNKDGEIIGEESILHTGDFRYNQSMNNYPLLKGRTISKLYLDNTYCDPQYVFPPQPEIIKQVASIVRKENDGETLFLFGTYVIGKERILLEIAKQEGKPVHVSNEKYAILCCLSTCLDINKFTTNELITPFRAVTMSMLSYHNMLSLLDSSNNKYKRVIGFRPTGWTQAKKSITYLNRGPTTFYSVAYSEHSSFNELRDCIDHFRPTQIIPTVDCDSPIKVKNILAHFSDLYEKKKQLTIASFFSAQPVTNFFQSFFKSKSEPIIDEDNKKLIPITTTTTTNINTLTATDTTTTKIKTSNTLIKDEFTDDLIWDCSDDLISDRKLLTQSDNSSALCKIEKEENFNDLSENNNNSNNNNNNNNNNNNNNNNNNNNNNNNNKLIIENDIKEEIIDFDDPVFISQQKWIEKQIYNNNNNSNNNNFTTPTKTNGNLSNNAKLNLTPTQTQTQTPTQNNKKQKTTNVSPTSYNSNNSSQQSGLKRSKSDPNVKKNQLQTSQPPSQSLITSFFQKCASPTSLFSATPPTPSITTTSNQSTKNKNSTTTTSTSTSNNKPFKN", "length": 920 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q86KX6-1", "protein_name": "TNF receptor-associated factor family protein DDB_G0272348", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEFELEDITIEQSSFTNNNSNNNNNNNNNSNSNNNNNNNNNNINNNNNHNNNNKNNSNNKNEINNQLDIPISNLVVDKENISKKYFCTICSDLLVNSFHADKFKAVQCKNGHYTTCLNCWEKHLEKKKNCIQCGVDVESIESLSSNLLVTQKFTTFKIHCPNSFFDTIDFIKDEVNGCKEIIQINELEEHLKECQYGFISCKNCEEFSKLPFQEFTQCPDFRKNTKEQHDLICPYVKISCEYCGDIINKINKESHNANWCQEITIKCLDCHLPFKKKEINQHQKSFCPETIIQCRYSKGGCNAMIRRSKLSQHLTEGDNHHQFISNILNQQDLKINELELKNTEFCLLLNGQNKKITELEILFKELNDSILIQKQQQKQQQQQQQQQQQQQQQQQQQQQSQQQQSQQQQQSQQQQQSQQSQQNNNSNSHFINNNNNNINNVQMSDSPNGGSLPQAVYKNKWVISNYSEQEQQGISKDYIKSPLFKIGNSTFFLKWFPFGKKKLNYCSIFLYKTQDDKSIIVNYYIHLVNNQISDEVYEKRGCQKYDSENGSAGYGSSQFIKRADLLNDANGFLINDSITIEIEIFATEEILPLQS", "length": 595 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q8BI41-1", "protein_name": "Syncytin-B", "gene_name": "Synb", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTGFWVLCFVLFPSSLSYPESWMPLVNLTHHILRDTNSSLFSNCWVCLSTQTQRSLAVPAPLSIWTDTPMKLHLTYSVRPFSGSFSISDIERRLRLFRPLTASYSFHNPDRRAIAFLQLVSSTGIFRIITRITSVIYPHKDRFFESAQRPLWGPLFTETVLRSQAPLCISRFFKVSAYATFVGNLSASLCNYTMHISPSTSHENLDLSTTHTFKQAMKRPDAKWKNPLRFSGPPSLIFSKPAYYPCPTDIKHCHTSPATPWMHCPQAPFGTCYNLTLFEPDNSTHPVTMSVNPTHFKVKLQGHRDPYPLSHYQPLTGAALSGQYSVWENEITVQENWDITSNIFSHLLSFSYAFCLNSSGVFFLCGTSTYICLPANWSGVCTLVFQYPDIELLPNNQTVPVPLFASVLSSDSVLRPKRSPHLFPFLAGLGISSALGTGIAGLATSTLYFQQLSKVLSETLEEIAASITTLQNQIDSLAGVVLQNRRALDLITAEKGGTCLFLQEECCFYVNQSGIVRDAARKLQERASELGQHSDSWGQWPDLGRWLPWLTPFLGPLLFLFFLLTFGSCLLNCLTRFVSQRLGSFVQDTAKRHVDSILQNFQYKKLPQDSPDEDTIPT", "length": 618 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8BYG0-1", "protein_name": "Tetratricopeptide repeat protein 24", "gene_name": "Ttc24", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSSRQYGLSDVLRALEESRKLADADRSTDQGLLGPFYNDLGMGYFQLQLFPLAVEAFLQALPLCRQPSEQATVLQNLGMTHNVLGNYWEAQEFHQKAASLHGSVGQRWEQGRSFSGLAFSLSQLGDHRAAWDSYLHALQAAQDTGDVKGQWQACEGLGAAAARLGQHDQALKYYKEALALCQHEPSSVRERLVAKLADAMRTFVAQEKIAQARFLPSAPGKLQTSRKAKTSARVQSSAEDAQESQWEGEASEGGHEKKEMEGLVNTATVLGPQRQNRATTHLPSGGPSPSGEEYPFIIAPKKLRVSRSSTWAKEALGRNFQRTRIQSGLCSIM", "length": 334 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8C1N8-1", "protein_name": "Alpha-defensin 22", "gene_name": "Defa22", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKKLVLLSALVLLAYQVQTDPIQNTDEETNTEEQPGEEDQAVSVSFGGQEGSALHEKLSRDLICLCRKRRCNRGELFYGTCAGPFLRCCRRRR", "length": 93 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8C1P2-1", "protein_name": "Alpha-defensin 21", "gene_name": "Defa21", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKTLVLLSALILLAYQVQTDPIQNTDEETNTEEQPGEDDQAVSVSFGGQEGSALHEKLSRDLICLCRNRRCNRGELFYGTCAGPFLRCCRRRR", "length": 93 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8C5Y2-1", "protein_name": "Mitochondrial sheath formation-associated protein", "gene_name": "Misfa", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MIVLGWMLFVGLATYMGTFPEAMPPTLKWKERLPGQENKARRRIQALEEELLL", "length": 53 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8CDW1-1", "protein_name": "Protein FAM228A", "gene_name": "Fam228a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MADTKTSKCDEHFSVEKLKEWPEPESVSLMELLAREDIDEAVHAVLFRENYVVKRLDTYLQHLAVFKERRKEMLHKKWVENVVQPLQQRITDKITSYRRPGKNQVKYEHCLKQTNKPTKVSSSCLFQKQQEFREAKGTSYQHGRGKTHDTQKEAKETEKGLSFTPFSLRPHCSSPRERQRASARLMQSKPGGRNRYKGASSEKPVFTLKSHLPKEEKTVSRSQLVFERQFRASRLSQDIKEAEKKGLVVGTGPQRPRSWAAADSVPRPSLVGRRVMTAEILGEHLVSLHQAARSGLQWP", "length": 299 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8CEK3-1", "protein_name": "Serine protease inhibitor kazal-like protein, minor form", "gene_name": "Spinkl", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSTWIKFLFILTLVLLPYSVFSVNIFAGPENVIKEPNCTMYKSKSECSNIAENPVCADDRNTYYNECYFCIEKVVEKLKYRYHGICIYK", "length": 90 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8IZP1-1", "protein_name": "TBC1 domain family member 3", "gene_name": "TBC1D3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDVVEVAGSWWAQEREDIIMKYEKGHRAGLPEDKGPKPFRSYNNNVDHLGIVHETELPPLTAREAKQIRREISRKSKWVDMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNTEEMKLKNPGRYQIMKEKGKRSSEHIQRIDRDVSGTLRKHIFFRDRYGTKQRELLHILLAYEEYNPEVGYCRDLSHIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQEHVVATSQPKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQALMPITRIAFKVQQKRLTKTSRCGPWARFCNRFVDTWARDEDTVLKHLRASMKKLTRKKGDLPPPAKPEQGSSASRPVPASRGGKTLCKGDRQAPPGPPARFPRPIWSASPPRAPRSSTPCPGGAVREDTYPVGTQGVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDVEGPWFRHYDFRQSCWVRAISQEDQLAPCWQAEHPAERVRSAFAAPSTDSDQGTPFRARDEQQCAPTSGPCLCGLHLESSQFPPGF", "length": 549 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8K072-1", "protein_name": "Receptor expression-enhancing protein 4", "gene_name": "Reep4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVSWMICRLVVLIFGMLYPAYASYKAVKSKNIREYVRWMMYWIVFAIFMAAETFTDIFISWFPFYYEFKMAFVLWLLSPYTKGASLLYRKFVHPSLSRHEKEIDACIVQAKERSYETMLSFGKRSLNIAASAAVQAATKSQGALAGRLRSFSMQDLRSIPDTPVPTYQDPLYLEDQVPRRRPPIGYRPGGLQGSDTEDECWSDNEIVPQPPVRPREKPLGRSQSLRVVKRKPLTREGTSRSLKVRTRKKAMPSDMDS", "length": 257 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8MP30-1", "protein_name": "Uncharacterized histidine-rich protein DDB_G0274557", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEIKYFLVLLVGFLLVLPSIVNPYRKGVTITNQQPKINIYQLDVNNPHNPNNNPHNPHNPNNNPHHPHHLHHHHHHHHHHHHHHHHHHHHHHHHHHPHHPHHHPHHHHHPHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHPHHHPHPHPHPHPHPHLHPNPHPHPHPHPHPHPHPHHHPNPNPHPHPHPHPHHHHHHQEASECLSYQGNRNRLFIKRDY", "length": 233 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q8NG83-1", "protein_name": "Olfactory receptor 2M3", "gene_name": "OR2M3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MARENSTFNSDFILLGIFNHSPTHTFLFFLVLAIFSVAFMGNSVMVLLIYLDTQLHTPMYLLLSQLSLMDLMLICTTVPKMAFNYLSGSKSISMAGCATQIFFYTSLLGSECFLLAVMAYDRYTAICHPLRYTNLMSPKICGLMTAFSWILGSTDGIIDVVATFSFSYCGSREIAHFFCDFPSLLILSCSDTSIFEKILFICCIVMIVFPVAIIIASYARVILAVIHMGSGEGRRKAFTTCSSHLLVVGMYYGAALFMYIRPTSDRSPTQDKMVSVFYTILTPMLNPLIYSLRNKEVTRAFMKILGKGKSGE", "length": 312 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8NGV6-1", "protein_name": "Olfactory receptor 5H6", "gene_name": "OR5H6", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MFLYLCFIFQRTCSEEMEEENATLLTEFVLTGFLHQPDCKIPLFLAFLVIYLITIMGNLGLIVLIWKDPHLHIPMYLFLGSLAFVDASLSSTVTPKMLINFLAKSKMISLSECMVQFFSLVTTVTTECFLLATMAYDRYVAICKALLYPVIMTNELCIQLLVLSFIGGLLHALIHEAFSFRLTFCNSNIIQHFYCDIIPLLKISCTDSSINFLMVFIFAGSVQVFTIGTILISYTIILFTILEKKSIKGIRKAVSTCGAHLLSVSLYYGPLTFKYLGSASPQADDQDMMESLFYTVIVPLLNPMIYSLRNKQVIASFTKMFKSNV", "length": 325 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8R264-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r215", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNWNNIIHTIIFLSLTGPGIVGNMLIFIRHIYMPALGTEKKPVDLIVIHLAFSNMITICTTGIKDIATVFYFRNFLGDIGCKAVVFLARMARGLSICTTCLLSVVQAITISPRTSLWTKLKPQTACQIIPFILVFWIFNGLISSNLLSYIKGGSSLNRSVAATFIGHCYMLQSRHTIKWIFLSLMTLRDVIFQSLMGWSSGSMALNLYKHHKRVLYLYSSRFANNSPPEIRATWSVLILMTCFLLFYWADFILSFYHGFTVTHESILLNIKVFLELGYVSFSPYVLISRYIHPPNVFHAH", "length": 300 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R272-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r220", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVLQFIKKTIFLFMTMVGILGNMSVSVHYMFSWWGSPEKKPIHLILTHLTFTNIILLLAKGLQKTIIVFGLRNFLDDIGCKIIVYLERVARGLSICTSSVLTVVQAIIISPRASGWRRLRPKSAWHILPFFSFFWILNAFISVNLIHSIRSKGMNTSQHKNSDDYCYLTPESQKIKWIVLPLMVLRDAVFQGAMGGASGYMVFLLHKHHQHVLYLQNSKLLYRTPPELRAAQSVLLLMLCFLFFYWTDCALSLFLSLSLGDSSLMINIQGFLTLGYAIFSPFVLIQRDGLIPVCWHAQ", "length": 298 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R278-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r213", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLALRNYIQINTPWCMCLFVTPLTPCLPEYWDPDSLRVEGPTESSLRHNTASCTLKNTIMQNVQFRSMSSITDAFFKMYLHTRKEEMILKILKEITFLIMTVLGILGNMSVSVNYMFSWWGSPEKKPIHLILIHLIFTNIIILLVKGLPKTIAAFGLRNFLDDIGCKIIVYMERLARGLSICTSSLLTVVQAIIISPRASGWRRLRLKSAWHILLFFLFFWILNALISVNLIHSTTNTRLNVSQLKSDDNYCYFMLPIQKIKWIVLPLMVVRDAVFQGAMGGASGYVAFLLHKHHQHVLYFQNSKLLYRTPPELRAAQSVLLLMLCFVFFYWTDCAFSLFLTLSSEVNILMVNTRDFLTLGYATFSPFVLIHRDGLLVECRHVQ", "length": 384 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R2A9-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r229", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDFGNLAMGIVLSLQSALGILGNFSLLFYYLVLYNKERTLKIIDIILIHVFTSNSLIIFSKGLPEVLAVFGWNDLFDDVGCKLIMYVRRVSRSMSISMTCLLSVFQAITISTRNSCWKEFKEQTAKFMGLFISLCWILFMLVNMLFPVYTSTNRNSKNKTQKKDIEFCHSVGRDKMVDIMYTAFCVFPEVLFSLLIVSSSTTMIVILYGHKKRVQHILHTHASPRTSAENRATQTILILVCTFLAFYTLSSVLQGYVALSHDPSWWVMNITTIISMGFPAIGPFVMSRDFTVSRFCFTCIGNLKLP", "length": 306 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R2B6-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r178", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHDKSLKTTDDMTLQILLLCQFVVGTVANVFLFLHNISPVLTGSKQRPRQLILSHMSVANALILFLTSFPDMMAFAPRNSPTHLKCKLEYFSRLVARSTNMCSTCVLSIHQFVTLVPVNRGKAILRASVPNLTSYSCYSCWFFSVLSNIYIAIKVTGPQITDNNTDSKSKLFCFTSGFSVGIFFLRIFHDGTFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQDARGQAETRATHTILMLVVTFVSFYLLNFICIIFYTFSIDSRLFMSHFSKVFAAGFPTISPLLLIFRDPKYPCSVLFNC", "length": 304 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R2B8-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r64", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSQNKTLKTMEVLALQILLLCQVVVGTVGNIFLFVHNFSPVLTDSRLRPIQVILINLAVANAFMLLLFAYSYDLIDFVPRKPPTDLKCKLAYFFNMVAQGTIMCSTCLLSTYQFVTLVPGNWARVMFREISPKVVSYCCYSCWLFSVLNNAYMPMYVSGPQKTHNDSDSKDNWICSISGVSVDMNFLRFSHDIIFIGIMAWTSVSMVIHLNRHHHRMHYLHNPNQINRGHAETKAAHTIMMLVVTFVSLYILDCICSLFHISFVESRLWLIDVIELLHLSFPTVSPFLLICRDPMGPCSLLFIVGLEIHVTVGAITEEQ", "length": 320 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R2B9-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r59", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEMLALQILLLCQVVVGTVGNILLFVHNFSPVLTDSRLRPIQVILINLAVANAFMLLLLTYSHDMIDFVPRKPPTDLKCKLAYFFHMVAQGTIMCSTCVLSTYQFVTVVPGTWARVMFREISPKVVSYSCFSCWLFSVLHNAYIPMNVSGPQKTHNDSDSKGNSICSISGVNVDMHFLRFSHDIIFLGIMAWTSVSMMIHLNRHHQRMNRIHKVNQNNRGHAETRAAHTILMLVVTFVSLYILNCISILFHISFVESRLWSRHVIKVLALSFPTISPLLLIFRDPRGHCSLLFSVGLEIHVTGGVITEEQ", "length": 310 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R2C0-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r62", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEVLALQILLLCHVVVGTVGNILLFVHNFSPILTDSRLRPIQVILINLAVANAFMLLLFAYSYDLTDIVPRKPPTDLKCKLAYFFHLVARGTIMCSTCVLSTYQFVTLVPGTWARVMFSEISPKVVSYCCYSCWLFSVLNNAYMLMNVSGPQKSHNDSDSKSNSICSISGVSVDMNILRFSHDIIFLSIMAWTSVSMVIHLHRHHQRMNHIHKVNQNNRGHAETRAAHTILMLVVTFVSLYILNCISILFYISFVESRLWLRYVTKLLALSFPTISPLLLIFRDSKGHCSLHIMSVWKST", "length": 300 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R4R9-1", "protein_name": "Protein phosphatase 1 regulatory subunit 14C", "gene_name": "Ppp1r14c", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSVVTGGGEAAGGTSGGGARVFFQSPRGGTGGSRESSSHSGSSREDSAPVATVAAAGQVQQQQRRHQQGKVTVKYDRKELRKRLVLEEWIVEQLGQLYGCEEEEMPDVEIDIDDLLDADSEEERASKLQEALVDCYKPTEEFIRELLSRIRGMRKLSPPQKKSV", "length": 164 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8R4V1-1", "protein_name": "NFAT activation molecule 1", "gene_name": "Nfam1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MESWLLRRGARVRCLHPPSWLPAWCFLCLLPVPQTLQLTGLVSLTHTSLPIMVSLANTDVFFSCRIEDFTRLQRDLPVKLFHTDIHGRRRWEKQINCQHRPGMENHTRDCMVKLSQANTSATGIYYFIVEGEETYQSDGVVILVRDTVYQPPAFKVQEALMLGFTSLMSVLGVLGTALLLWKKKQISVLGKHTAKTCSGLKSTVGTTKPPAESVYTSLQRRETEVYACMKEETGSPVFSQSPATKEKLNRFEDDNEFNLVYENL", "length": 264 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8T277-1", "protein_name": "5'-AMP-activated protein kinase subunit gamma", "gene_name": "prkag", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MWYPGDEDEEFTSIIENIEKKETQEIKIKTEKLRQASLNQLPIEQSEGVGGGELSEYNNNTTNNNTPTNTTTTTNTNTTTMNNSNNNNERILSTSNGFDIRLPPNSIEQPSPSFISSSQDGVLTVDPLAVDGEKGNKESQSPPNGDNQILNNNNMFFKDITSLPSTDNKSSTNTNNNNNENPLKQTISSSPSKSTTTTTTSTSTTTTPSLSSLSSNNNNNSNSNNNYINHSSISTVSEGLENLNLKSGIKKIDSETEKYIEEGKQVFVNFLKGHTCYDVIPISGKVVVLDTKLAVKSAFYALEENGIKSAPLWNSEQHDFTGMITVSDFIDILLYYYKKPKSNNIFQDMGIHRIETFWREISVERPSSLISTEPETNLYDAASLLLCYKIHRLPVVDKKDTNSILHILTHSRILAFMMKSFPQLPEKLLSIPIGSLGIGTFATVVTVMTHTPLVEVLELLSEKKISAVPIIDSETSKIVDVYSKSDVTLMSKQGILSPSDLNLPVHQVLSTFTKLWQRPEQIYTCTRFDKLGDVIERCIKKRVHRLVCIDSSKKVEGILSLSDILNYLLNDVKSINH", "length": 577 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q8VEU4-1", "protein_name": "Olfactory receptor", "gene_name": "Or14j2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MIVENITTMRGFLLMGFSDNHELQILQALLFLVTYLLGSAGNVIIITITTLDPQLQSPMYYFLKHLSILDLSSLSVTVPQYVDICLTQSGYISYAQCMLQIFFFTGFAWGEVAILTVMSYDRYVAVCLPLHYEVIMGPSKCRWAVTAVWLSSVIPGTLYIASIFSIRFCGDRIIHQFFCDVPQVLKFSCSDDYLVTVGVADFLSAVAFACFIGIVNSYVHIFSTVLRMPSAESRSKVFSTCLPHLFVVLLFLSTGIFAYLNPTSDSPTALQFLVSIFYTVLPPTLNPVIYSLRNETIKSVIRKLLLSSKFTG", "length": 312 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8VFX0-1", "protein_name": "Olfactory receptor", "gene_name": "Or5b101", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MENRTEVRCFILVGLTNDPSLQLPLSITFLLIYIITLIGNLGLILMILLDSRLHTPMYIFLGNLSLVDFCYSSTVTPKVIAGFLTGDKIMSYNACASQMFFFANFGDVENYLLASMAYDRYVAVCKPLHYATTMTTHMCASLVIGCYICGFLSASIYTMDALSLSFCESNVIHHFFCDVLAVMIVSCSDSHVNELILIYVVSFNMFFALIIILISYMFIFTNILKIHSSAGYHKAVSTCASHFTAVSIFYGTIIFMYLQPSSSHTMDTDKIASVFYTMVICMLNPLVYSLRSKDVKSAFTKIVLRSK", "length": 307 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8VY69-1", "protein_name": "Vesicle-associated membrane protein 723", "gene_name": "VAMP723", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MAQQSLFYSFIARGTVILVEFTDFKGNFTSVAAQYLENLPSSNNKFTYNCDGHTFNDLVENGFTYCVVAVDSAGREIPMAFLERVKEDFYKRYGGEKAATDQANSLNKEFGSNLKEHMQYCMDHPDEISNLAKAKAQVSEVKSLMMENIEKVLARGVICEMLGSSESQPQAFYIKRTQMKRKKWFQNMKIKLIVLAIIIALILIIILSVCGGFNCGK", "length": 217 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q8VZ67-1", "protein_name": "Uncharacterized zinc finger CCHC domain-containing protein At4g19190", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MDGEGEGSGIRLSKRFAGGKVTGGSLEVDYKTKSGTAWSHSFLNQKPWHPLSYPNQRRKWIAEQTHAQHDRRAEEVAREFAQEQEFFKQAALISKKEREKIETMKAVSFMYVRPPGYDPESAKAAEYKDEKHKGQGSSTQDPVADDNVGSRPEESQGGGERTQERKKPRPKDVFGRALPTEEEFEVLKNAPRMETGIPGRVKPFAVEVRNVKCLRCGNFGHQSGDRDCPLKDAVMPNEELRLKRDDPLTAIIAHTDPSEPLKWELKQKPGLSPPRGGFDPDDPNQQIVAEDIFDEYGGFLEGSIPIEILKSMSSDKKRKSKKNKRHKKHSSRTVEETDESSTGSEDSREKRGSKKRKKLKKKSKKQYDSDSLSFEGSGSDSYRLSRRRHTKHVDPSASLKSEVYHQGNSHREKHYYDEKHQKRKEIVDRPSASSDDSDYYRSNSSRKKRSEDDYKSHHRERKQVHSNDPVSEKSQKQHYSESGKIQRVEKEHRYDERRHRYVDMESENRNRSEKKPRYDDRDSEKHHRSVKGKEKHVYEASDDPEEFSDRYRSTKKTESDSESNRRSRKKKHELSSEEEEGESRKHRYSTNRRRN", "length": 595 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q91V82-1", "protein_name": "Beta-defensin 8", "gene_name": "Defb8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRIHYLLFTFLLVLLSPLAAFSQKINEPVSCIRNGGICQYRCIGLRHKIGTCGSPFKCCK", "length": 60 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q923B3-1", "protein_name": "Neurotrophin receptor-interacting factor 1", "gene_name": "Nrif1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASTLPTTWPHESVKFEDVSLTFTEEEWAQLDFQQKCLYREIMMENYSNMISVEHHFSKPNVISQLEKAEDCWPMQREIPQDTLPECSWPSPDPGMNSFPSKSPLMKIEVVEVLTLNKDVAGPRNALIQSLYPEDLNPGNLKPAQQPSKRLTDTEASRQKFRHFQYEESAGPQKAMSQLRKLCHQWLQPNTRSKKQILELLVLEQFLNALPEKFRVWVESQHPEDCKAVVALLENMTSVSKDDASLACSSEATDQLKEKRKGVATLPVTFAAEVPAEEPVTFQDVAVDFNEEEWRLLGPTQKTEYHDVMLETLGNLVSVGWEPTLGNRELTPDSPIPVVKPIHDPNTNDLSRNGTQSTVFESILEDGVKEMHSIESNQVGNLQEKGHPQKKFSESSKSQDQTSRHKSQGSLNEVLPRKYVKVKQKGTGKRKGRTNTISMTRGLRIRKQQKDSVEWQGRSGSTPVTHGSSIKKQQQGSEQGKPGTSRDPITLTVPAKVYQKATGSEESIFMDSSDAMVPDVPPKIHQKGPEWHKVGESNNSMLQGSSVQNHQMESGAGRASDNSLLTHALPVKSHQKGYKEGNVQGNRNSWKHIKPHQKGSKGERVEELSTSEKHVPYVKNHLKTSERGKDREINASIKCDPYIKTYYRGSDVGRLRRANNCRKAFSLHAQQISFIKIHKGSQVCRCSECGKLFRNARYFSVHKKIHTGERPYMCMACGKAFVQSSSLTQHLRIHSGERPFECSECGRTFNDRSAISQHLRTHTGAKPYHCERCGKAFRQSSHLTRHERTHTGERPYVCIKCGKAFTQSSHLIGHQKTHGIKFKKQPKL", "length": 828 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q924S2-1", "protein_name": "Inactive 2'-5' oligoadenylate synthetase 1C", "gene_name": "Oas1c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MENGLCSIQARELDEFICDYLFPDTTFLTELRADIDSISAFLKERCFQGAAHPVRVSRVVMGGSYDEHTALKGKSEAKMVLFFNNLTSFEEQLKRRGEFVEEIQKHLCQLQQEKPFKVKFEVQSSEEPNSRSLSFKLSSPELQQEVEFDVQPAYDVLYELRNNTYAEPQFYNKVYAQLIHECTTLEKEGDFSICFTDLHQNFMRYRAPKLWNLIRLVKHWYQLCKEKLREPLPPQYALELLTVYVWEHSNKNQEKVTTAKNFRTFLELVAYYKNLRIYWTWYYDFRHQEVCAYLCRQLKKARPLILDPADPTRNVAGSDLQAWDLLAKEAQTWMQSSCFRNCDMSFVPTWDLSPERQECAFQ", "length": 362 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q925U0-1", "protein_name": "Oocyte-secreted protein 1", "gene_name": "Oosp1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKPFVGLLGLLLLLSFMKTCADDWTAISLQCADHWFHLRIRPTIFHNIFMEPDEVFLGIGCPVTTTWPNDTYEFIYRTYSCGIANKVLCDVTLLKTQLTYISKNASLQAEMSLSCVMHNQSPHFCEAESRGDFTGDPPGWTEDMRARRDEQTVPMVQPNLSTSSEDHHVSTEPWASETSRSEAAEVPSFMDQNFSVFHFSRM", "length": 202 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q94490-1", "protein_name": "Ubiquitin conjugating enzyme E2 B", "gene_name": "ubcB", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MAAHKRLQKEITDMLKTPPSWCSAHLVDDNLQKWKATVQGPEGSPFEKGVFSMDIDIPADYPFKPPTLKFTTKIYHPNIKTSDGAICAEVFSTWSPQLKILDVLTTIRSILTDPNPDNPLETEIAQQFKTDRNAFNKTAKEWTKKYAK", "length": 148 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q945S5-1", "protein_name": "Vacuolar cation/proton exchanger 4", "gene_name": "CAX4", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSSISTESSSNLSLLENGGGGSDKPTAETSRRVRRTVSASSLIRKRSDLKLISRVRWEFMRRILTNLQEVLLGTKLFILFPAVPLAVVAHRYDCPRAWVFALSLLGLTPLAERISFLTEQIAFHTGPTVGGLMNATCGNATEMIIAILAVGQRKMRIVKLSLLGSILSNLLFVLGTSLFLGGISNLRKHQSFDPRQGDMNSMLLYLALLCQTLPMIMRFTMEAEEYDGSDVVVLSRASSFVMLIAYLAFLIFHLFSSHLSPPPPPLPQREDVHDDDVSDKEEEGAVIGMWSAIFWLIIMTLLVALLSDYLVSTIQDAADSWGLSVGFIGIILLPIVGNAAEHAGAVIFAFRNKLDITLGIALGSATQIALFVVPVTVLVAWTMGIEMDLNFNLLETACFALSILVTSLVLQDGTSNYMKGLVLLLCYVVIAACFFVSNSPSSKLLF", "length": 446 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q96AK3-1", "protein_name": "DNA dC->dU-editing enzyme APOBEC-3D", "gene_name": "APOBEC3D", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNPQIRNPMERMYRDTFYDNFENEPILYGRSYTWLCYEVKIKRGRSNLLWDTGVFRGPVLPKRQSNHRQEVYFRFENHAEMCFLSWFCGNRLPANRRFQITWFVSWNPCLPCVVKVTKFLAEHPNVTLTISAARLYYYRDRDWRWVLLRLHKAGARVKIMDYEDFAYCWENFVCNEGQPFMPWYKFDDNYASLHRTLKEILRNPMEAMYPHIFYFHFKNLLKACGRNESWLCFTMEVTKHHSAVFRKRGVFRNQVDPETHCHAERCFLSWFCDDILSPNTNYEVTWYTSWSPCPECAGEVAEFLARHSNVNLTIFTARLCYFWDTDYQEGLCSLSQEGASVKIMGYKDFVSCWKNFVYSDDEPFKPWKGLQTNFRLLKRRLREILQ", "length": 386 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q99N64-1", "protein_name": "Germ cell-less protein-like 2", "gene_name": "Gmcl2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9C7P4-1", "protein_name": "Putative zinc finger CCCH domain-containing protein 9", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MADAGDNQQEAERRSDETESRSIKEPKEKEDEDENPQDQIQSKERMRQSSPYPVRPGKKDCQFYLKNGLCRYRSSCRFNHPTQRPQELPVRICKHIMDRNVAEPMYQDWRESESERRFDERTQRTFGDERTQRRYGIEYSGARPEKRSKIVPDFQMRDPRHHDTEWRFERERMERIERQRREAEENLQEQRQRDSIERQRREAEENLQEQRQRDSIERQRREAQENLQQQRQRDSIERQRREAQENLQQQRLQDMPENHNVDDQQNLQEQRRISIEKERTEARLRLEQIRPTVSFPINEFIRAVVLLRELIENWDDKAWKK", "length": 321 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9C8M4-1", "protein_name": "DNA-directed RNA polymerase subunit 12-like protein", "gene_name": "NRPB12L", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MDLQQSETDDKQPEQLVIYVCGDCGQENILKRGDVFQCRDCGFRILYKKRILDKKETRIGV", "length": 61 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9CQK8-1", "protein_name": "Small proline-rich protein 2A1", "gene_name": "Sprr2a1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSYYQQQCNQPCRPPPVCPPPKCPEPCPPQVWPGPCRPVMCFEPCLPSVWPGPCRPVVCYEQCPPQPWQSTCPPVQFPPCQQK", "length": 83 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9CWP4-1", "protein_name": "Lymphocyte antigen 6K", "gene_name": "Ly6k", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAFLVALLVVLGLQLVQSNALTCHVCEAQNSYACSNPSQCPGEKKFCLLAVTRIFERFFYVSKQCTRRCPTPVVSPPSTNPPSEPKEFLIEKPMPFLFYKCCQWDSCNGEGPPTDQLLKEQPGKASGRRHRYIELLLTGFMVLTANGLSALCLL", "length": 154 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9D541-1", "protein_name": "Coiled-coil domain-containing protein 7A", "gene_name": "Ccdc7a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKCAKHPSTISMKLTSVPELPYKKGLLNSSPKPKEKHNAKSKYGKNESMVLRSPPTGESIVRFALPIPLSKTKDKISADEMVRRITTNLKMVVSNLEDTYGACYDNGEKAAEKSEAEGLSIGDDVSSFLLCCSQFTSQLEEAVKEECGALESLYKWFQQQVNQMEEISKDQSNLEELQSDGKTASLNIVQIAKLARKFEDFKSRLKTRKEVMQTKNEDKEIMAETLKHYGLMEKQIEEFITSHSALESQTETESQSGTPSVTTRMARMIKIFENQSTMLEKALNDQQTIESKYKQLETDFQMLIMEKTLLEAEIRRLREIERVKSAAKEEQTKKSGKSEKKKFKEKEKNLSPNREFKSIEELLQIQKEAELLKTEKKTLQGQLKWALEEAERNKTQLEFVLHQKMEMFKEESKTKVGQSQNKSKVKIEDSKDSLPKKSDTQLGGQRKDQISSDQSKRPKKKQLADIDPSAVEDFPPETFKSFTVMPLIEEHRESISSQPKEEMAKASEQSEAEDIEGPLEIPSESSNEDDDLLPEDESPMMEQVTDVGRYKSIYISAEPIDTMSLISRTQSEMETLEAINYDNVLNEGEEQDKKIGKDSDTGRKSKRKRSSKIRKLSTHEEESDIVHYEEATKAKVPSKKRASDPYGDEAYESRGSVSKAQTYTKKQGTHQRGRGSASDAYGDEAYESRGSISKAQTYTRKQGTHQRGRGSVQEEESDTVHYEEVTRAKVPSKKQASDPYGDEAYESQGSVSKAHTHTKKQGTHQRGRGSVHEEESDTMNYEVPRKSKISSRRKGFALPITHQVEMHSSESQGSISKSNTETKKQGTHKRGRDSDADGARTPVSQGSDSKADTERKKHRSKEESTISKDSIPVLDEVQDKTFEHQESGLRLEVQAKKLTFSSQNIHNEESATDIKVEYQNVPSSSQVQLKKQKPLGGEIFTTHFVVPAESHAQLYQTHTPETQIERGTTSGTARLTTIPVEHPKKEASPDNLFPEKKLYITRAPTQTKKQYPPWDAKAETQKKTVKEVQGISEPQTKLNPTMSGIILHLDMDRVVETDLENLEETIVPHVLRSELEIGTDAKNMPETPTSREAVRTEAKGNQDVTISIAKGMKLIGKLKDQHGLSSFASKDTISPGKSLIKSSRDNQDDSLLETKPQENTSDKYHPSKTFPTKVINMLPFSEKSLGSTSANVDVAPKPVYRASRGRSRISKALQQLLKTSEHLKPTSTKNQNADLEKHLYISVRSANKHTQKDKKHGQSNNQKLKKQGALSSTKKQKHKEQPKTETIVENNDKFDDNLMMTTSSPNIKIIKELSKTLNLDGGDIELSDFVFKTASAAKKLENKGPSKTKNLNKESSRDIHILHLTTSAIRTLLLDEEAKIRSLEKKLMKQSTILQKSVSSMKKFMFEEPSRETKMKRKKREKRKIVVKSPHILPITTTQKHTIKEKSEISNLEKPIVRGTDILKKSTSARKKRVLKGKSKSATLPKKCDNFPFDLVRSSSDSSKQEVEEQPKPGNVDKKVSDDSYSPDISTTPTKKHTLKGQSKSRTIYEKGVDLPNNLVLSKSASSIQEFEEQPQPGNVDKKVSDDSYSPDISTSPTKKHTLKGQPKSENSDEKGIKRPNNLHMSASVARKRLLKALSTIP", "length": 1642 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9D5R2-1", "protein_name": "WD repeat-containing protein 20", "gene_name": "Wdr20", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MATEGRGKETNEIKTHFTTREGLYRLLPHSEYSRPNRVPFNSQGSNPVRVSFVNLNDQTGNGNRLCFSVGRELYVYIYKGVRKAADLSKPIDKRIYKGTQPTCHDFNHLTATAESVSLLVGFSAGQVQLIDPIKKETSKLFNEERLIDKSRVTCVKWVPGSDSLFLVAHSSGNMYSYNVEHTYGTTAPHYQLLKQGESFAVHNCKSKSTRDLKWTVGEGALNEFAFSPDGKFLACVSQDGFLRVFNFDSAELHGTMKSYFGGLLCLCWSPDGKYIVTGGEDDLVTVWSFLDCRVIARGRGHKSWVSVVAFDPYTTSVEESDPMEFSDSDKNFQDLLHFGRDRANSTQSRLSKQNSTDSRPVSVTYRFGSVGQDTQLCLWDLTEDILFPHQPLSRARAHANVMNATGLPAGSNGSAVTTPGNSVPPPLPRSNSLPHSAVSNAASKGSVMDGAITSGVSKFALLSLHDRKERHHEKDRKRNHSMGHISSKSSDKLNLVNKAKTDPAKTLGTSLCPRMEDVPLLEPLICKKIAHERLTVLVFLEDCIVTACQEGFICTWARPGKVSKFQP", "length": 567 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9DAF8-1", "protein_name": "Uncharacterized protein C4orf51 homolog", "gene_name": "", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTHFLYLTPEILLPFSPLTSTEFELIRRKAQQLWQDETRWSASSMTTYSGSYREKQLDEATCNRLAQRVGQPQFEYKPTPLPGSSAYNTLPGHAGSQEAADGKGRLPDIASPSRDSPLNIKHKVAHQIWGSEVPCPTFLAYRGLRMSPCMQPKKPGFELLMSYRNRGKALLKRLQRQWDYESKLGSSEDSGTDRFSSNTSGSSGRKFK", "length": 208 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9EPV9-1", "protein_name": "Beta-defensin 5", "gene_name": "Defb5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKIHYLLFAFLLVLLSPLAGVFSKTINNPVSCCMIGGICRYLCKGNILQNGSCGVTSLNCCKRK", "length": 64 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9EPX4-1", "protein_name": "P2Y purinoceptor 12", "gene_name": "P2ry12", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEVPGANATSANTTSIPGTSTLCSRDYKITQVLFPLLYTVLFFAGLITNSLAMRIFFQIRSKSNFIIFLKNTVISDLLMILTFPFKILSDAKLGAGHLRTLVCQVTSVTFYFTMYISISFLGLITIDRYLKTTRPFKTSSPSNLLGAKILSVAIWAFMFLLSLPNMILTNRRPKDKDITKCSFLKSEFGLVWHEIVNYICQVIFWINFLIVIVCYSLITKELYRSYVRTRGSAKAPKKRVNIKVFIIIAVFFICFVPFHFARIPYTLSQTRAVFDCNAENTLFYVKESTLWLTSLNACLDPFIYFFLCKSFRNSLMSMLRCSTSGANKKKGQEGGDPSEETPM", "length": 343 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9ER80-1", "protein_name": "Receptor-transporting protein 4", "gene_name": "Rtp4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLFPDDFSTWEQTFQELMQEEKPGAKWSLHLDKNIVPDGAALGWRQHQQTVLGRFQCSRCCRSWTSAQVMILCHMYPDTLKSQGQARMRIFGQKCQKCFGCQFETPKFSTEIIKRILNNLVNYILQRYYGHRKIALTSNASLGEKVTLDGPHDTRNCEACSLNSHGRCALAHKVKPPRSPSPLPKSSSPSKSCPPPPQTRNTDFGNKTFQDFGNRTFQGCREPPQREIEPPLFLFLSIAAFALFSLFTR", "length": 249 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9FFP9-1", "protein_name": "Serine/threonine-protein kinase SRK2H", "gene_name": "SRK2H", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MDKYEVVKDLGAGNFGVARLLRHKETKELVAMKYIERGRKIDENVAREIINHRSLRHPNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEAEARYFFQQLICGVDYCHSLQICHRDLKLENTLLDGSPAPLLKICDFGYSKSSLLHSRPKSTVGTPAYIAPEVLSRREYDGKHADVWSCGVTLYVMLVGGYPFEDPDDPRNFRKTIQRIMAVQYKIPDYVHISQECRHLLSRIFVTNSAKRITLKEIKKHPWYLKNLPKELTEPAQAAYYKRETPSFSLQSVEDIMKIVGEARNPAPSSNAVKGFDDDEEDVEDEVEEEEEEEEEEEEEEEEEEDEYEKHVKEAHSCQEPPKA", "length": 360 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9FLZ3-1", "protein_name": "SNF1-related protein kinase catalytic subunit alpha KIN12", "gene_name": "KIN12", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MDGSSEKTTNKLVSILPNYRIGKTLGHGSFAKVKLALHVATGHKVAIKILNRSKIKNMGIEIKVQREIKILRFLMHPHIIRQYEVIETPNDIYVVMEYVKSGELFDYIVEKGKLQEDEARHLFQQIISGVEYCHRNMIVHRDLKPENVLLDSQCNIKIVDFGLSNVMHDGHFLKTSCGSPNYAAPEVISGKPYGPDVDIWSCGVILYALLCGTLPFDDENIPNVFEKIKRGMYTLPNHLSHFARDLIPRMLMVDPTMRISITEIRQHPWFNNHLPLYLSIPPLDTIDQAKKIEEEIIQNVVNIGFDRNHVVDSLANRIQNEATVAYHLILDNRNQNSVPNDPFQSKFKEISDGIFNSTLPVQNITSHVGHSFSALYGLKSNVKDDKTWTLGLQSQGSPYDIMTEIFKALQNLKICWKKIGLYNIKCRWVRSFAYYKNHTIEDECAIILPTVIKFEIQLYKVREGKYLLDILRIDGPQFIFFDLCVAFLRELGVL", "length": 494 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9FVV4-1", "protein_name": "DEAD-box ATP-dependent RNA helicase 55", "gene_name": "RH55", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MDSSPPNTIIEEAPPRFSELKPPLSEDIIEALDRSGFEVCTPVQAETIPFLCSHKDVVVDAATGSGKTLAFLLPFIEIIRRSNSYPPKPHQVMGVIISPTRELSAQIHKVARAVRLDFAKCREVEADMNTLEEEGANLLIGTPGRLSDMMKRMEFLDFRNLEILILDEADRLLDMGFQKQVNYIISRLPKQRRTGLFSATQTQAVADLAKAGLRNPYLKCEADQKSSQLVHLLIENKNKKLVVFFMTCACVDYWGLVISKIPSLKSISFFPTHGKMDQKGRDTALASFTEASSGVLLCTDVAARGLDIPGIVYIRSLAIKDREVLEKGLKAFVSFVRAYKEHQCSYIFSWKGLEIGKLAMGYGILSFPYISEVKQDRIGIVGFTPVQGITFEDIKFKNKSREKQRQQNLLARKDKLQQEKRGKRKKSSKEAVDDSNKASRKRKLTGRQRQTIQTAQDEEEMNLRL", "length": 465 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9JI02-1", "protein_name": "Secretoglobin family 2B member 20", "gene_name": "Scgb2b20", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKGTLLLLGLLVTGELSFQTTEACLPFFEGYASVLSGSRVWLYQELQAFNATAEEKVALEKIQDCFSEERIRNILLEPKIMEAMVASPECLSYYGLDNIRSILDYISKLLGE", "length": 112 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9JJQ7-1", "protein_name": "X-linked lymphocyte-regulated 4B", "gene_name": "Xlr4b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASKIKGRPPKQPKVTPALPSNDSQQLHENNPGNNLALETCGESSSSHGTGGPKPGPSKKTLNERKRKYGVSVNKTVQNIEWNVDHFLKVQHERRQELYKDYSHQFLTLVMMWNIDVDQIKKQAGKLSDILDEQQKLFQQFQSIHMQKIEEFKELCDRHLKNLQAIKCCRRKAIIEEARKLMDYLEKRVTEETVHVNKQEAKDGVQSSLLSLLIS", "length": 215 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9JLV9-1", "protein_name": "Prolactin-2C5", "gene_name": "Prl2c5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLPSLIQPCSWILLLLLVNSSLLWKNVASLPMCAMRNDRCFMFFEDTFELAGSLSHNISIEVSELFTEFEKHYSNVPGLRDKSPMRCHTSFLPTPENKEQARHIRYEALLKSGDMILDAWENPLDYLVSELSTIKNVPDIIISKATDIKKKINAVQNGVNALMSTMNGDEENKNPAWFLQSDNEDARIRSSYGMISCLDNDFKKVDIYLNILKCYMLKIDNC", "length": 222 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9LJY9-1", "protein_name": "Cytochrome P450, family 705, subfamily A, polypeptide 18", "gene_name": "CYP705A18", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MATLISVDFQHCFMYIILLCLFSLLCYSLFFRKPKGTRVGCDLPPSPPSLPIIGHLHHLLSSLTHKSLQKLSSKYGPFLHLRIFSVPIILVSSASVAYEIFKAHDVNVSSRGAAAIDESLLFGSSSFIYAPYGDYWKFMKKIFATKLLRPQVLENSRGVRAEELKRFYRRILDKARKNENIEISKESAMLMNNILCRMSMGRSFSEENGEAERVRGLVGESYALVKKIFFAATLRRLLEKLRIPLFRKEIMGVSDRFDELLERIIVEHKDKLEKEHQVMDMMDVLLAAYRDKNAEYKITRNHIKSFFVDLFVGGTDTSVQTTQWTMAEIINNPNILQTLRKEIDSVVGKSRLIHETDIPNLPYLQAVVKEGLRLHPPGPLLIRTFQERCEMKGFYIPEKTTLVINAYAVMRDPDSWEDPDEFKPERFLSYSRSGQEDEKEQTLKYLSFGGGRRGCPGVNLGYIFVGTAIGMMVQCFDWKIEGDKVNMEETYGGMNLTMVNPLKCTPVPRTQPFSFTSNLEILSS", "length": 524 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9LSY1-1", "protein_name": "SKP1-like protein 8", "gene_name": "ASK8", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSTKKIMLKSSEGKTFEIEEETARQCQTIAHMIEAECTDNVILVLKMTSEILEMVIEYCNKHHVDAANPCSDDDLEKWDKEFMEKDKSTIFALTNAANFLNNKSLLHLAGQTVADMIKGNTPKQMREFFNIENDLTPEEEAAIRRENKWAFE", "length": 152 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9LTG5-1", "protein_name": "Callose synthase 4", "gene_name": "CALS4", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MNQPNRGQILQTVFSHFFPVASPDSELVPSSLHEDITPILRVAKDVEDTNPRSLFLQDLDIKSVDDSINILSGHSHALDKANELDPTSSGRDVRQFKNTILQWLEKNNESTLKARQKSSDAHEMQSFYQQYGDEGINDLLNAGAGSSSSQRTKIYQTAVVLYDVLDAVHRKANIKVAAKILESHAEVEAKNKIYVPYNILPLDPDSKNHAMMRDPKIVAVLKAIRYTSDLTWQIGHKINDDEDVLDWLKTMFRFQKDNVSNQREHLILLLANVQMRQTQRQPNLLDDRALDTVMEKLLGNYNKWCNHVGLESSLRFPKDKQQKVVQQRKLLYTGLYLLIWGEAANLRFMPECLCYIYHHMAFELFEMLESKGSKKKYKPKNPTYSGKDEDFLTKVVTPVYKTIAEEAKKSGEGKHSEWRNYDDLNEYFWSKQYLDKLGWPMKANADFFCKTSQQLGLNKSEKKPDLGDGCVGKVNFVEIRTFWHLFRSFDRMWSFYILSLQAMIIIAWNETSESGGAVFHKVLSVFITAAKLNLFQAFLDIALSWKARHSMSTHVRQRYIFKAVAAAVWVLLMPLTYAYSHTSIFIVAILIYLSPNMLPEMLLLIPSIRRTLEKSDFRPVKLIMWWSQPELYIGRGMHESAWSIYKYMMFWIVLLTSKLAFSYYVEQIKPLMGPTKEIMSVPMPGYWLPEFFPHVKNNRGVVITLWSPVILVYFMDTQIWYAIVSTLVGGLYGAFRHIGEIQTLGMLRSRFQSLPGAFNACLIPNENTKEKGIKLAFSRKCHKIPNTNGKEAKQFSQMWNTIINSFREEDLISNRELELLLMSCWAYPDLDFIRWPIFLLASKIPIAVDIAKKRNGKHRELKNILAEDNCMSCAVRECYASIKKLLNTLVTGNSDLMLITTVFTIIDTHIEKDTLLTELNLSVLPDLHGHFVKLTEYVLQNKDKDKIQIVNVLLKILEMVTKDILKEEIKRLHLLLTVKESAMDVPSNLEARRRLTFFSNSLFMEMPGAPKIQNMLSFSALTPYYSEDVLFSTFDLEKENDGVSILFYLQKIFPDEWKNFLERVKCGTEEELDAIDYLKEEIRLWASYRGQTLTKTVRGMMYYQKALELQAFFDLANERELMKGYKSAEASSSGSSLWAECQALADIKFTYVVACQQYSIHKRSGDQRAKDILTLMTTYPSLRVAYIDEVEQTHIYSKGTSENFYYSALVKAAPQTYSTDSSDSGHMLDQVIYQIKLPGPPIIGEGKPENQNNAIIFTRGEALQTIDMNQDYYIEEAFKMRNLLQEFLEKNGGVRYPTILGLREHIFTRSVSCLAWFMSNQEHSFVTIGQRVLANPLKVRFHYGHPDVFDRVFHLTRGGVSKASKVINLSEDIFAGFNSTLREGTVSHHEYIQVGKGRDVGLNQISMFEAKIANGSGEQTLSRDLYRLGHQFDFFRMLSCYFTTVGFYFCSMLTVLTVYVFLYGRLYLVLSGVEKELGNKPMMMEIILASQSFVQIVFLMAMPMIMEIGLERGFYDALFDFVLMQLQLASVFFTFQLGTKFHYYCKTLLHGGAEYRGTGRGFVVFHAKFAENYRFYSRSHFVKATELGILLLVYHIFGPTYIGLFTISIWFMVGTWLFAPFLFNPSGFEWHEIVEDWADWKKWIEYDNGGIGVPPEKSWESWWEKDIEHLQHSGKWGIVVEIFFALRFFIFQYGLVYQLSAFKNKYSSLWVFGASWLLILILLLTVTVLDYARRRLGTEFQLLFRIIKVSLFLAFMAIFITLMTCRLILPQDVFLCMLALIPTGWGLLLIAQSCKPLIQQPGIWSWVMTLAWVYDLVMGSLLFIPIAFMAWFPFISEFQTRMLFNQAFSRGLHISRILSGQRKHRSSKNKD", "length": 1871 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9LU95-1", "protein_name": "Pyruvate kinase", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MEMLLGGQATNGALRSKTKIVCTLGPASRSVEMIEKLLKAGMNVARFNFSHGSHSYHQETLDNLRTAMDNTGILCAVMLDTKSPVIRTGFLKEGKPIQLKQGQEITISIDYKIQGDSNTISMSYKKLAEDLKPGDVILCSDGTISLNVLSCDKYLGLVRCRCENSALLGERKNVNLPGIVVDLPTLTEKDKEDIMQWGVPNKIDIIALSFVRKGSDLIQVRKLLGEHSKSIMLMSKVENQEGVMNFDKILENSDAFMVARGDLGMEIPIEKMFLAQKTMINKANAHGKPVVTATQMLESMTVSPRPTRAEATDVANAVLDGTDCVMLSGETAAGAHPETAVLTMSRICKEAEDFIDYDILHKKTLGMVSLPLSPIESLAASAVSTARSVFASAIVVLTRGGYTAELVAKYRPSVPILSVIMPEIAECSDSVAHVARRGLIYRGIIPVVGCSARDSTEEMIRLAIGFAKTKGICKTGDSIVALHKIDGSSIVRIVSVE", "length": 497 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9LX08-1", "protein_name": "Annexin D6", "gene_name": "ANN6", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MASLKIPANIPLPEEDSEQLHKAFKGWGTNEGMIISILAHRNATQRSFIRAVYAANYNKDLLKELDGELSGDFERVVMLWTLDPTERDAYLANESTKLFTKNIWVLVEIACTRPSLEFFKTKQAYHVRYKTSLEEDVAYHTSGNIRKLLVPLVSTFRYDGNADEVNVKLARSEAKTLHKKITEKAYTDEDLIRILTTRSKAQINATLNHFKDKFGSSINKFLKEDSNDDYVQLLKTAIKCLTYPEKYFEKVLRRAINRMGTDEWALTRVVTTRAEVDLERIKEEYLRRNSVPLDRAIANDTSGDYKDMLLALLGHDHA", "length": 318 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9LXS7-1", "protein_name": "Citrate synthase 1, peroxisomal", "gene_name": "CSY1", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MEISERARARLAVLNAHLTVSEPNQVLPAIEPWCTSAHITAAPHGSLKGNLKIVDERTGNEYQVPVSEHGTVKTVDLKKITTGKDDKGLNLYDPGYLNTAPVRSSISYIDGDEGILRYRGYPVEELAEKSTYTEVTYLLIYGNLPSQRQLADWEFAISQNSAVPQGVLDMIQSMPNDVHPVGALVTAMSALSIFYPDANPSLMGLGVYKSKQVRDKQIVRVLGQAPTIAAAAYLRKAGKPPVQPLSNLSYSENFLYMVESMGDRSYKPNPRLARVLDILFILQAEHEMNCSTAAARHLSSSGGDVYTAVSGGVGAIYGPLHGGAVEATINMLSEIGTVENIPEFIESVKNKKRRLSGFGHRIYKNYDPRGKVVKKLADEVFSILGRDPLVEVGDALEKAALSDEYFVKRKLYPNVDFYSGLINRAMGIPSSFTAVSRIAGYLSHWRESLDDPDTKIMRPQQVYTGAGIRHYETVRERTKL", "length": 480 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9LY06-1", "protein_name": "Glycine/proline-rich protein", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MITCILKISISSFIVLRIFSFLWFSRWFCCGLCGRFWFRCWFCCWFQFWFRCRFYCRFDTGFDVRFAAGFAADLTIGFTIGFDSGFATFLDVGLDDGFATGLDISFAGGFVTGFATDFDVGFDTGFTIGFDTGFDVGLPAVFSIGFDTGFAVGFAISFTVGFDAGFPTGFFVSLDVGFVADFVIGFATGIGVGFEVDFATDFDTCFATGFAVSFDVGFAGGFSIGFAADFANGFTVGFDGGFDASFFVGLDVGFVVGFVTSFAAGLDVGFAIDFATGFDTGFAFGLAFGFDVGFAAGFAVGFATGFTVVFDVGFASDFFVGLDVGFLTGFATDFDIGFVVDFDIGFATGFVVGFDDGSIVGLVVGLPASLDDGLAIDFVVGLDIGFVTGLFVGLVDGLTTDLDVGLVDGLDDGLDDGLDVDLVVVGFVVDGLAVDLDVGLGVGLTVGFVDGLDVGFDDGLDADTVDGLDVGLDDGLDVDLVDGLDIGLDDGLDVGLDDGLDFGLVDGLDVDLDDGLDVDLVDGLDIGLDDGLDVGLDDGLDFGLVDDGLVVGLFDVFVGTGLSWEIPPPGKLPPDASPLGIGSFGVGPPGASPFIASPSGEGPLSEGLLGIRSFGISPLSIRPLGISPLGISPPNIEPSKADASDADPSNAGPLGISPLSIDPPVAGASDEGPLGKLPPDLSPPGKGSSGEGPLVESPPSEGPLGVDPLGAGSLGISPLGKSPLRIRPLGISPFGKIPSNIDPSSALASDGGPPDEPASAEGSPDVGIFGISPPIIDPPVEGASDGDPPEKLSLDISPLGKGPSGVSLLGAGPPGVGPVIASPPGEGPRDAGPLGAGSLGISPLNIRRLGISPSGISPPNIDLPVAGTSIGGPPDEGASDGGPPDVGPFGISPPIIDPPGESESDGDPAGKLPLDISPLSKGPSCVSPLGVGPVIASPPGEGPLDAGPLGAGSLGISPLNIRRLSISPFGISPSSIDSPVAGTSIGGPPDEGASDGGPPDVGPFGISPPIIDPPGEDASDGDPPGKFPLDISPLGKCPSGVSPLGVGPPGVGPVIASPPGEGPLDAGPLGAGSLGISPLNIRRLGISPFGISPPNIDLPVAGTSIGGPLDEGASDGGPPDVGPFGISPSIIDPPGEGAFDGDPPGKLPLDISPVGKGPSGVSPPGAGPPGDGPVIASPPGESPLDAGPLGAGSLGISPFGISPPNIDWPVAGTSFGGPPGEGASNGGPLVVGPFDMPVVGASDGDALEKLPLDISLPGKGPSDVGPPGAGLPGAAPPGVDLSNVGASDRGASGEGASDGCPPDVGPFDICLLSIDPPVVGASDGGPPDEGASNGGPPDTDSFGGDPLCASPLGIDPPIVDASDGDPFGAGSPDEDPSNENASGEGASGESPPCSDVSCKGPSSAGASIGCSLDNGASTPSSPDTFLSNVFPSDKSSPDAFSPDVAALVTLPSGKDPFDISPPIVALLDVSPLGKTSSDAYSSGISPGIFEKSFPLVKLQTIEYM", "length": 1504 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9M2S0-1", "protein_name": "Probable mannose-1-phosphate guanylyltransferase 2", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MKALILVGGFGTRLRPLTLSLPKPLVDFANKPMILHQIEALKAIGVDEVVLAINYEPEQLLVMSKFSNDVEATLGIKITCSQETEPLGTAGPLALARDKLVDGSGQPFFVLNSDVISDYPLEEMIAFHNAHGGEASIMVTKVDEPSKYGVVVMEEATGRVERFVEKPKLFVGNKINAGIYLLNPSVLDRIELRPTSIEKEIFPQIAEAEKLYAMLLPGFWMDIGQPRDYITGLRLYLDSLRKKSPSKLATGPHILGNVLVDETAEIGEGCLIGPNVAIGPGCVVESGVRLSHCTVMRGVHVKRYACISSSIIGWHSTVGQWARVENMSILGKNVYVCDEIYCNGGVVLHNKEIKSDILKPDIVM", "length": 364 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9NR96-1", "protein_name": "Toll-like receptor 9", "gene_name": "TLR9", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGFCRSALHPLSLLVQAIMLAMTLALGTLPAFLPCELQPHGLVNCNWLFLKSVPHFSMAAPRGNVTSLSLSSNRIHHLHDSDFAHLPSLRHLNLKWNCPPVGLSPMHFPCHMTIEPSTFLAVPTLEELNLSYNNIMTVPALPKSLISLSLSHTNILMLDSASLAGLHALRFLFMDGNCYYKNPCRQALEVAPGALLGLGNLTHLSLKYNNLTVVPRNLPSSLEYLLLSYNRIVKLAPEDLANLTALRVLDVGGNCRRCDHAPNPCMECPRHFPQLHPDTFSHLSRLEGLVLKDSSLSWLNASWFRGLGNLRVLDLSENFLYKCITKTKAFQGLTQLRKLNLSFNYQKRVSFAHLSLAPSFGSLVALKELDMHGIFFRSLDETTLRPLARLPMLQTLRLQMNFINQAQLGIFRAFPGLRYVDLSDNRISGASELTATMGEADGGEKVWLQPGDLAPAPVDTPSSEDFRPNCSTLNFTLDLSRNNLVTVQPEMFAQLSHLQCLRLSHNCISQAVNGSQFLPLTGLQVLDLSHNKLDLYHEHSFTELPRLEALDLSYNSQPFGMQGVGHNFSFVAHLRTLRHLSLAHNNIHSQVSQQLCSTSLRALDFSGNALGHMWAEGDLYLHFFQGLSGLIWLDLSQNRLHTLLPQTLRNLPKSLQVLRLRDNYLAFFKWWSLHFLPKLEVLDLAGNQLKALTNGSLPAGTRLRRLDVSCNSISFVAPGFFSKAKELRELNLSANALKTVDHSWFGPLASALQILDVSANPLHCACGAAFMDFLLEVQAAVPGLPSRVKCGSPGQLQGLSIFAQDLRLCLDEALSWDCFALSLLAVALGLGVPMLHHLCGWDLWYCFHLCLAWLPWRGRQSGRDEDALPYDAFVVFDKTQSAVADWVYNELRGQLEECRGRWALRLCLEERDWLPGKTLFENLWASVYGSRKTLFVLAHTDRVSGLLRASFLLAQQRLLEDRKDVVVLVILSPDGRRSRYVRLRQRLCRQSVLLWPHQPSGQRSFWAQLGMALTRDNHHFYNRNFCQGPTAE", "length": 1032 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9QUG3-1", "protein_name": "Prion-like protein doppel", "gene_name": "Prnd", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKNRLGTWWVAILCMLLASHLSTVKARGIKHRFKWNRKVLPSSGGQITEARVAENRPGAFIKQGRKLDIDFGAEGNRYYAANYWQFPDGIYYEGCSEANVTKEMLVTSCVNATQAANQAEFSREKQDSKLHQRVLWRLIKEICSAKHCDFWLERGAALRVAVDQPAMVCLLGFVWFIVK", "length": 179 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9SAC9-1", "protein_name": "AP-1 complex subunit mu-1", "gene_name": "AP1M1", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MAGAASALFLLDIKGRVLVWRDYRGDVTAAQAERFFTKLIETEGDSQSNDPVAYDNGVTYMFVQHSNIYLMIASRQNCNAASLLFFLHRVVDVFKHYFEELEEESLRDNFVVVYELLDEMMDFGYPQFTEARILSEFIKTDAYRMEVTQRPPMAVTNSVSWRSEGLKFKKNEVFLDVIESVNILVNSNGQIVRSDVVGALKMRTYLSGMPECKLGLNDRILLEAQGRAIKGKAIDLEDIKFHQCVRLARFENDRTISFIPPDGSFDLMTYRLSTQVKPLIWVEAHIERHSRSRVEMLVKARSQFKDRSYATSVEIELPVPTDAYNPDVRTSLGSAAYAPEKDALVWKIQYFYGNKEHTLKADFHLPSIAAEEATPERKAPIRVKFEIPKFIVSGIQVRYLKIIEKSGYQAHPWVRYITMAGEYELRLM", "length": 428 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9SCN2-1", "protein_name": "Cytochrome P450 71B31", "gene_name": "CYP71B31", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSMFLGLLFLFPLFFILFKNLLPPRKKLPPGPTGLPLIGNLHQLGRLLHSSLHKLSLEHGPVMLVRWGVVPMAVFSSNEAAKEVLKTHDLETCNRPKLVANGLFTHGYKDIGFTQYGEEWREMKKFVGLELFSPKKHKSFRYIREEEGDLLVKKISNYAQTQTLVDLRKSLFSYTASIIFREAFGQNFRECDYINMDKLEELVQETETNVCSLAFTDFFPRGLGWLVDRISGQHSRMNIAFSKLTTFFEDVIDELLKTKQLDDHSDLVTAMLDVINRPRKFGSLKITYDHLIAMMSDVVLAGVNAGTVTMIWTMTELTRHPRVMKKLQEEIRATLGPNKERITEEDLEKVEYLNLVIKESFRLHPPAPLLLPRETMSDIEIQGYHIPKNAHVKINTYAIGRDPKRWTNPEEFNPERFLNTSINYKGQHYELLPFGAGRRNCPGMTLGITILELGLLNILYYFDWSLPSGMTIKDIDMEEDGALNIAKKVPLQLVPTLP", "length": 498 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9SJ39-1", "protein_name": "Cytochrome P450, family 705, subfamily A, polypeptide 6", "gene_name": "CYP705A6", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MAAILSVDFQNCFIFIVLCLFSLFCYSLFFKKPKHPRGCDLPPSPPSLPIIGHLHLLFSPLTHKSLQKLSSKYGHLLHLRIFNVPVILVSSASVAYEIFRAHDVNVSSRGVAAIDESLLFGSSGIITAPYGDYWKFMKKLIATKLLRPQSLESSRGIRGEELTRFYNSLLDKARMTESVEISTEAMKLVNNTLCRMSMGRSFSEENGEAEKIRGLVGESYALTKKMFLASLLRKPLKKLRISLFEKEIMGVSDRLDELLERILVEHEEKLHEEHQGTDMMDVLLAASGDENAEYNITRNHIKSFFVEIFIGATDTSVQTTQWTMAEILNHPNVLERLRKDIDSVVGKTRLIHETDLPNLPYLQAVVKEGLRLHPPGPLLVRTFQERCKIKGFYIPEKTTLVINAYAVMRDPDSWEDPDEFKPERFLRAPPMGGSLDKFIEFS", "length": 442 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9SMT4-1", "protein_name": "Large ribosomal subunit protein eL13y", "gene_name": "RPL13C", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MKHNNVIPNGHFKKKWENYVKTSFNQPAMKTRRRIARQNKAVKIFPRPTAGPIRPVVHAQTLTYNMKVRAGKGFTLEELKAAGIPKKLAPTIGISVDHHRKNRSLEGFQTNVQRLKTYKAKLVIFPRCARTVKVGDSAQQELANATQVQVDHMPIVREMPTMELVKLTSDMKLFNAYDKIRLEGINKRHAGVRAKRAAEAEKEEKK", "length": 206 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9SSB4-1", "protein_name": "26S proteasome regulatory subunit 7 homolog B", "gene_name": "RPT1B", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MIIRDIMEDPENEGPHNMRSDFEPLLSVLRLRDYETGDIIEFDSTEASEEALSDITEFGSTEASEAHFEEPYSARIKKVEKEINELAEKICNLGIKESDTGLAPPNQWDLVSDKQMMQEEQPLLVATCTQIISPNTEDAKYVVDIKKIGKYVVGLGDKASPTDIEAGMRVGVDQKKYQIQIPLPPKIDPSVTMMTVEEKPDATYSDIGGCKEQIEKIREVVELPMLHPEKFVRLGIDPPKGVLCYGPPGSGKTLVARAVANRTGACFIRVVGSELVQKYIGEGARMVRELFQMARSKKACILFFDEIDAIGGARFDDGVGSDNEVQRTMLEILYQLDGFDARGNIKVLMATNRPDILDPALLRPGRLDRKVEFCLPDLEGRTQIFKIHTRTMSCERDIRFELLAGLCPNSTGADIRSVCIEAGMYAIGARRKSVTEKDFLDAVNKVVKGYQKFSATPKYMAYYI", "length": 464 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9SVM4-1", "protein_name": "Serine hydroxymethyltransferase 5", "gene_name": "SHM5", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MEPVYSWGNTHLDFVDPEIYDLIEKEKHRQCRGIELIAAENFTSVAVMEALGSCLTNKYSEGMPGNRYYGGTEFIDEIESLCRSRSLEAFHCNPEKWGVNVQPYSGSPANFAAYTALLQPHDRIMGLDLPSGGHITHGYYSSGGKNISATSIYFENLPYKVDSKTGYIDYDKLEEKAMDFRPKLIICGGTSYPREWDYARFRAVADKVGAFLLCDMAHNSALVAAQEAADPFEYCDVVTTSTHKSLRGPRAGMIFYRKGPKPAKKGQPEGEVYDFDAKINSAVFPALQSGPHNNKIGALAVALKQVMAPSFKVYAKQVKANAACLASYLINKGYTLVTDGTDNHLILWDLRPLGLTGNKVEKVCELCYITLNRNAVFGDTSFLAPGGVRIGTPAMTSRGLVEKDFEKIGEFLHRAVTITLDIQEQYGKVMKDFNKGLVNNKEIDEIKADVEEFTYDFDMPGFFISESRND", "length": 470 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9SWH4-1", "protein_name": "Syntaxin-42", "gene_name": "SYP42", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MATRNRTTVYRKHRDACKSARAPLSLSASDSFGGPVIEMVSGSFSRSNHSSYAPLNSYDPGPSSSDAFTIGMPPAWVDDSEEITFNIQKVRDKMNELAKAHSKALMPTFGDNKGIHREVEMLTHEITDLLRKSEKRLQMLSTRGPSEESNLRKNVQRSLATDLQNLSMELRRKQSTYLKRLQQQKEGQDEVDLEFNVNGKMSRLDEEDELGGMGFDEHQTIKLKEGQHVSAEREREIQQVLGSVNDLAQIMKDLSALVIDQGTIVDRIDYNVQNVSTSVEEGYKQLQKAERTQREGAMVKCATILLVLCLIMIVLLILKNILF", "length": 323 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9SYN6-1", "protein_name": "SOUL heme-binding family protein", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MEAALSIFKLSFLLTLLSGGSDLIDSLPPNCNRAECPSYEVVHAGNGYEIHRYNTTVWISTEPIQDISLNEASGNGWNQLSDYMNGNNDYHQRIEIALPYITQVSQNLSTFIVSFFVPKAFQPDPPPGNNLHVQRWDSRYVAVKQISGYVADHKIGKQVAELKASLQGTVWAKAIEKSRETGGVGSAWAYTVAQFSWPFQWSQRVNEIWFPFEMEDEETVSIVTQ", "length": 225 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9SZB4-1", "protein_name": "Putative DEAD-box ATP-dependent RNA helicase 43", "gene_name": "RH43", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MEVDDGYVEYVPVEERLAQMKRKVVEEPGKGMMEHLSDKKKLMSVGELARGITYTEPLSTWWKPPLHVRKMSTKQMDLIRKQWHITVNGEDIPPPIKNFMDMKFPSPLLRMLKDKGIMHPTPIQVQGLPVVLSGRDMIGIAFTGSGKTLVFVLPMIILALQEEIMMPIAAGEGPIALVICPSRELAKQTYDVVEQFVASLVEDGYPRLRSLLCIGGVDMRSQLDVVKKGVHIVVATPGRLKDILAKKKMSLDACRLLTLDEADRLVDLGFEDDIRHVFDHFKSQRQTLLFSATMPAKIQIFATSALVKPVTVNVGRAGAANLDVIQEVEYVKQEAKIVYLLECLQKTTPPVLIFCENKADVDDIHEYLLLKGVEAVAIHGGKDQEDRDYAISLFKAGKKDVLVATDVASKGLDFPDIQHVINYDMPGEIENYVHRIGRTGRCGKTGIATTFINKNQSEITLLDLKHLLQEAKQRIPPVLAELNGPMEETETIANASGVKGCAYCGGLGHRILQCPKFEHQKSVAISSSRKDHFGSDGYRGEV", "length": 542 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9T0E0-1", "protein_name": "Putative ATPase, plasma membrane-like", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MATGDSLEDIKIEIDDDLEKIPIEEVFKKLRCSREGLSGAEGKERLKIFGPNKLENKKKEHITLRFFALMFKPLSWVIQAAAIMAMLFANGDGRQLFLGIVCLLIVNTIICYLKEDDAANVVAMARAGLSPKTKVLRDGKWSEQEASILVPGDIVSIKPGDIIPCDARLLEGDTLKVDQSALTGEFGPITKGPGEEVFSGTTCKQGEMEAVVIATGVHTFSGTTAHLVDNRTNKVGHFRKVVTEIENLCVISIAIGISIEVIVMYWIQRRNFSDVINNLLVLVIGGIPLAMPTVLYVIMVTGSLRLYRTGTITQRITAIEDMAAIDVLCSDKTGTLTLNKLSVDKNLIKVYSKDVEKEQVLLLAARASRIENRDGIDAAMVGSLADPKEARAGIREVHFNLVDKRTALTYIDGNGDWHRVSKGTPEQILDLCNARDDLRKSVHSAIRNYAERGLKSFAISWFRNTNCNTVFFFPYQLCSEHKYHIVNKLQERHICGLIGDGVDDVPSLKKADVGIAVANATEAARAASDIVLTEPGLSVIIDAVLASRAILQQMKHYTIYAVSITIRVVFGFMFIALIWKFDFSPFMVLAIALLNEETTKAITMDNVTNPSPTPDSLKLKEIFATGVVYGSYMALITVVFFWAAYRTDIFPRTFHVRDLRGNEAEMMCALYLQVSIMSQALFFVIQSRSWFFVERPGELLFLSFVTVQTIATTLAVYASWETARIEGIGWSWAGVIWLYNIIFFFPLDIMKFGIRYILTGKAQSLFDNMVHLVLNSYAKLSNGIYNHTQADHTYSLLEVSTPPSQDLRGVGWV", "length": 813 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9T0H7-1", "protein_name": "Histone H2A.8", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MVCNTNILKDVSTKISAFENVRMIMVEGEMFQVARIHKQLKNRVSAHSSVGATDVVYMTSILEYLTTEVLQLAENTSKDLKVKRITPRHLQLAIRGDEELDTLIKGTIIGGSVIPHIH", "length": 118 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9VXF6-1", "protein_name": "Calnexin 14D", "gene_name": "Cnx14D", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MAWKMLFAILLLLSAAKTGYLAPESENSVEDVQIEPGAIYGDEKFAYKSPVIDAEKFYFADHFDDVEASRKRWVLSQAKKNDIADEIAKYDGIWNWESPQRIFWANDLGLVLKSKAKHAAIAAPFRQPFDFKSNKPLVVQYELTLQEGQDCGGSYLKLLSAGKGTEQLNRFNDKTPYTIMFGPDKCGNNLKMHFIFRHVNPLNGNITEKHCKKPNARLGVPFTDKLPHLYQLVVRPDNSFEIRLDHKIIKEGSLLTDFVPPVNPPAEIDDPNDHKPESWDERKKIPDPNAHKPEDWDEDAPPHLPDTDAVMPNGWLEDEPDMIFDPTAIEPEDWNSEIDGEWEAPLVENPVCKKAPGCGKWKAPLIPNPNYKGKWSAPMIENPNNQGKWAPRKIANPDFFEDLKPFQMTPINAVGLELWSMSSDILFDNLIITDDVELARDFAANSFDIKRLYIDRESFGNKVVELARANRAIWGIVIVAIAVPVAITIFCKFGLGPSRVAAAKKAAAAAAKKTDDPQPDDDLGAEEEEKLEKGKKEEEKKEEEEEEEKEENKEEKKEEEKDDEKEMKDCEEEEDDEEKDDEEKTDERAAGDTNKESTPLSASPKKNQKSYLDNNEDEEDTLKNKEPTPKKRKRKALKE", "length": 639 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9W240-1", "protein_name": "K Homology domain-containing protein", "gene_name": "cg3927", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "METPSELTEKQNQDQPTYQPRLNEVAQKFLADLDAERKRLSAEFPLCALLIDESVDRVYSTGRIPGKEPFADVYQQKPMKIIQKVFVPVNKFPKFNFTGKILGPKGNSLRRLQEETHCKIVIKGRNSMRDRNKEEELRSSGDPRYAHLHKDLFLEVSAVAPPAECYARIAYALAEIRKYLIPDDNDDVWHEQQRELMEMNPKSAKKSNGLNMAPYRSNFDKAIGAIRNRAPKYNNQIRRVTENPREVAYMEEVEYDYDEHLMFCSPVVRL", "length": 270 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9W4G6-1", "protein_name": "Uncharacterized protein", "gene_name": "Dmel\\CG2861", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MDYEIIEFVRRHISHIDISAETRMRYPDPISNNNFDWNSIGLGEQEDAIGQDQQSQALNENANNVSPDVPPSTIAEPTLEPSTIEGNQGQNPRIISSMPDMMPMANSFNPLININQEAGVVINTGINSIDNGLPSTYSEHISQPTNTESTRNMNSSIFDIPSDLDNNSSNESGDEVTQPTAKQSKINANFVCKIESDTNMDKLPTTSNNTNDKPPNNTDSDSDIISISDLIEDLNLDFNQLPITSCDVETHPADTQSNIDANLPYDLISAINMDFVNPANRTYMSAANSTRGTAYKIRKPRTVKRIIKAPSKSNIGKLLREAAKKENAAAGTQRPKKATSTITSSVQNFPNPNNWPACPFPMQNGTMPADEPNDLMPTVSQSLTVPAAQNRPIQTIGKIIKPPVKRTYTKRANKTNNTNIPNKNSTGVIQSNGVAPTIRQGLVEPGGTNILMPWNRQIPMVSVAENPRVQTIDKIIVPPPKRTYKKRVNKTVNTNQSSESAVGDGAPSAPIQSIPKVRKPRGPGKKTAKMVPGQESQQDIPLGVPPNGEAPQTSSQAPVPRVKRAYRKRANNTNNTNILNVNSTGVMESNGGGPTIPNSQQIPNVAVVLNLPIQPIKPKAPRKPRAKKVCNQQPGTDIPFGVSAQGQTAQIKPKPKPRAPRVPKEPKAPKEPKAPKVPKAPRVPKAPRVPKAPRVPKAPRVPKPPKEPKPPKEPKPPKQPKAPRVPKEPKPPKVPKEPKAPRAPRAPRVPKAPKEPKVPKIPKNPRVPKAPRQPKASMNKIQNTVKVPLPIEPVPLETPTYINPINTPVQSTVGEILALGSMPPISPIKFPVLFDEHAAQHTVANSNMPQSSLPTLDIPQLPTRNNKQPSTKSAEDTEILGLGKNKNAMKSDGRIKQGRVSKPSLRFSPSSSSLRPVVRSLSSSSSSSSSWSSCTTCSTCSSCSTCSSSSDSSQSSRSRNRKRRSPKVPIPHKLFESNGEINFQLGQPTRLESPSPPPPVPMQACGTFEEHLTDLTLVRVHAISPLRSPTYDFDFDLPEPMLSEESSSSSSESNDESNVNCQMAPNSQNVSMHFLKVMVFYNCYVLFQQLEKKHQSLFEESSSSSSSESNDETNVNCQMTPNSQNQKKLQSAPIREPSPDQPPEAASRSSNGGTIGPCNLKAFRRDFMISNAENTGFTNPSELNLKKCATKVCTPMERNSGSQLPIQNRFILPNSNKEEGKMNVEPVMPKHKPSRIPIRTKTPIALNLMKEPEDNARKPKNILKPFFSNADVNPCSSTDYEPNFKPCESPLPAKQNDFKLINKDKKSWVSHYQEQESQELKENSFFYAKFNLPNIPKKSFKDSKANAERRCTKTFEDVRKEAQQSRYTKAINKRQNKKAMLESALGNAITEDPTVNCNLADNPNDQVEMPRNPDIVEPTVKPVKFKAFVSASIKPKSSKKRKLMNSASNSKLFKFKIFESEVNKDENEEEDVIPDNLIIPVKRKQNISELLDMQPSTSKAAATITSQPKIAQLKRMPSKLLNEKMKSYAKKRSNDDENKDTKNTGMHMHRYKIPKLSANKPQNTSTTQSPTRGFSRLPGMYQEPNFQNAQHPFSTRGYYPYQRAYPLHRPTSQYHMNQPQPLRLHHSMYVDAEPSFESVFPAPRYQPYNINPSMRHHYSYPGEPSPSTYPMGGIPFQNNNTLYPPMRNDLCYPRGRLNYPVRNLPPMNSQGTYPPNYPQNFLPNYPPSRQFLLSMQRLADINKQIASGSIESVGGFIQMAYAGRKYRTLKDLRERTMLSKDSLRKIFKCMCKIKRPKWRISKFYLYAYWCEISGIPQSSEFGKPLELNAAYRKVISSYAENKFLRMESLMEKTGFGKSKLKRVLKMIGRKRSTKWRLLNYRKPLIHLHRSQDM", "length": 1893 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9W6A5-1", "protein_name": "Green-sensitive opsin-1", "gene_name": "opn1mw1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MNGTEGSNFYIPMSNRTGLVRSPYDYTQYYLAEPWKFKALAFYMFLLIIFGFPINVLTLVVTAQHKKLRQPLNYILVNLAFAGTIMVIFGFTVSFYCSLVGYMALGPLGCVMEGFFATLGGQVALWSLVVLAIERYIVVCKPMGSFKFSANHAMAGIAFTWFMACSCAVPPLFGWSRYLPEGMQTSCGPDYYTLNPEYNNESYVMYMFSCHFCIPVTTIFFTYGSLVCTVKAAAAQQQESESTQKAEREVTRMVILMVLGFLFAWVPYASFAAWIFFNRGAAFSAQAMAVPAFFSKTSAVFNPIIYVLLNKQFRSCMLNTLFCGKSPLGDDESSSVSTSKTEVSSVSPA", "length": 349 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q9XK79-1", "protein_name": "NADH-ubiquinone oxidoreductase chain 4L", "gene_name": "nad4L", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNLIDLILIAIYVIGISGLIFNKNNIINILIISELNLGTLGMLFVLASVELNDILGELSGLYILTFTAAESAIGLAIVVILYSKTGIINIRHLNKLKG", "length": 98 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q9Y2B0-1", "protein_name": "Protein canopy homolog 2", "gene_name": "CNPY2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKGWGWLALLLGALLGTAWARRSQDLHCGACRALVDELEWEIAQVDPKKTIQMGSFRINPDGSQSVVEVPYARSEAHLTELLEEICDRMKEYGEQIDPSTHRKNYVRVVGRNGESSELDLQGIRIDSDISGTLKFACESIVEEYEDELIEFFSREADNVKDKLCSKRTDLCDHALHISHDEL", "length": 182 }, "evidence": [ { "id": "A0A8V0YDY5", "url": "https://omabrowser.org/oma/group/A0A8V0YDY5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9Z1X0-1", 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"https://www.uniprot.org/uniprotkb/A0A8V0YKD2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MHCPCARSPLPLPSSRDRAPAHKLSKGSKDMQMGAGGRQANPSSPGLPSLLPLFPSQIPHIPRGCGSLYSFPSPSPSNGAIVEGLAGLDVHLLSTFMQYFLPALLTRPSVPPPAPHTCQGLAPCLPEEGQVNTSGPRLPCAILHPTSGGSSAAMDGIFCALPLSLLLLLQSCGVWGAPPQPRGTLCRTKPTDLVFIIDSSRSVRPQEFEKVKVFLSRVIEGLDVGPNSTRVGVINYASAVKNEFSLKTHQTKAGLLQAVQRIEPLSTGTMTGLAIQFAISRAFSDTEGARLRSPNINKVAIVVTDGRPQDGVQDVSARARQAGIEIFAIGVGRVDMHTLRQIASEPLDDHVDYVESYSVIEKLTHKFQEAFCVVSDLCATGDHDCEQICISTPGSYKCACKEGFTLNNDGKTCSACSGGSGSALDLVFLIDGSKSVRPENFELVKKFINQIVESLEVSEKQAQVGLVQYSSSVRQEFPLGQFKNKKDIKAAVKKMAYMEKGTMTGQALKYLVDSSFSIANGARPGVPKVGIVFTDGRSQDYITDAAKKAKDLGFRMFAVGVGNAVEDELREIASEPVAEHYFYTADFRTISNIGKKLQMKICVEEDPCECKSIVKFQTKVEELINTLQQKLEAVAKRIEALENKII", "length": 646, "header": "tr|A0A8V0YE02-1|A0A8V0YE02_CHICK Isoform 1 of Matrilin-1 OS=Gallus gallus OX=9031 GN=MATN1 PE=4 SV=1 CANONICAL=A0A8V0YE02-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YE02-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE02/entry#A0A8V0YE02-1", "sequence": { "sequence": "MHCPCARSPLPLPSSRDRAPAHKLSKGSKDMQMGAGGRQANPSSPGLPSLLPLFPSQIPHIPRGCGSLYSFPSPSPSNGAIVEGLAGLDVHLLSTFMQYFLPALLTRPSVPPPAPHTCQGLAPCLPEEGQVNTSGPRLPCAILHPTSGGSSAAMDGIFCALPLSLLLLLQSCGVWGAPPQPRGTLCRTKPTDLVFIIDSSRSVRPQEFEKVKVFLSRVIEGLDVGPNSTRVGVINYASAVKNEFSLKTHQTKAGLLQAVQRIEPLSTGTMTGLAIQFAISRAFSDTEGARLRSPNINKVAIVVTDGRPQDGVQDVSARARQAGIEIFAIGVGRVDMHTLRQIASEPLDDHVDYVESYSVIEKLTHKFQEAFCVVSDLCATGDHDCEQICISTPGSYKCACKEGFTLNNDGKTCSACSGGSGSALDLVFLIDGSKSVRPENFELVKKFINQIVESLEVSEKQAQVGLVQYSSSVRQEFPLGQFKNKKDIKAAVKKMAYMEKGTMTGQALKYLVDSSFSIANGARPGVPKVGIVFTDGRSQDYITDAAKKAKDLGFRMFAVGVGNAVEDELREIASEPVAEHYFYTADFRTISNIGKKLQMKICVEEDPCECKSIVKFQTKVEELINTLQQKLEAVAKRIEALENKII", "length": 646, "header": "tr|A0A8V0YE02-1|A0A8V0YE02_CHICK Isoform 1 of Matrilin-1 OS=Gallus gallus OX=9031 GN=MATN1 PE=4 SV=1 CANONICAL=A0A8V0YE02-1" }, "locus": { "chromosome": "23", "start_pos": 636722, "end_pos": 620644, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032257.1", "url": "https://www.ensembl.org/id/ENSGALT00010032257.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019047.1", "url": "https://www.ensembl.org/id/ENSGALP00010019047.1" } ] } }, { "isoform_ac": "A0A8V0YKD2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE02/entry#A0A8V0YKD2-1", "sequence": { "sequence": "MQYFLPALLTRPSVPPPAPHTCQGLAPCLPEEGQVNTSGPRLPCAILHPTSGGSSAAMDGIFCALPLSLLLLLQSCGVWGAPPQPRGTLCRTKPTDLVFIIDSSRSVRPQEFEKVKVFLSRVIEGLDVGPNSTRVGVINYASAVKNEFSLKTHQTKAGLLQAVQRIEPLSTGTMTGLAIQFAISRAFSDTEGARLRSPNINKVAIVVTDGRPQDGVQDVSARARQAGIEIFAIGVGRVDMHTLRQIASEPLDDHVDYVESYSVIEKLTHKFQEAFCVVSDLCATGDHDCEQICISTPGSYKCACKEGFTLNNDGKTCSACSGGSGSALDLVFLIDGSKSVRPENFELVKKFINQIVESLEVSEKQAQVGLVQYSSSVRQEFPLGQFKNKKDIKAAVKKMAYMEKGTMTGQALKYLVDSSFSIANGARPGVPKVGIVFTDGRSQDYITDAAKKAKDLGFRMFAVGVGNAVEDELREIASEPVAEHYFYTADFRTISNIGKKLQMKICVEEDPCECKSIVKFQTKVEELINTLQQKYILWKLKAIEPK", "length": 546, "header": "tr|A0A8V0YKD2-1|A0A8V0YKD2_CHICK Computationally mapped isoform of Matrilin-1 OS=Gallus gallus OX=9031 GN=MATN1 PE=4 SV=1 CANONICAL=A0A8V0YE02-1" }, "locus": { "chromosome": "23", "start_pos": 636434, "end_pos": 623374, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032254.1", "url": "https://www.ensembl.org/id/ENSGALT00010032254.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019044.1", "url": "https://www.ensembl.org/id/ENSGALP00010019044.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YE02", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE02" } ], "pmid": "" }, { "name": "extracellular matrix", "id": "GO:0031012", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031012", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YE02", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE02" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YE02", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE02" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 132, "end_pos": 134, "annotation": "n_glycosylation_sequon" }, { "start_pos": 227, "end_pos": 229, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YE02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE02" }, { "id": "PS50234", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50234" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "VWFA", "eco_id": "ECO_0000259", "start_pos": 192, "end_pos": 367, "start_aa": "Asp", "end_aa": "Phe", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 132, "end_pos": 134 }, { "start_pos": 227, "end_pos": 229 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YE07-1", "uniprot_ac": "A0A8V0YE07", "uniprot_id": "A0A8V0YE07_CHICK", "mass": { "chemical_mass": 66402.0, "monoisotopic_mass": 66402.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Bardet-Biedl syndrome 10", "type": "synonym", "evidence": [ { "id": "A0A8V0YE07", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE07/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YE07", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE07" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE07", "locus": {} } ], "crossref": [ { "id": "A0A8V0YE07", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YE07", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR027413", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027413", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042619", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042619", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR14667", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14667", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14667:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14667:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YE07", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE07", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YE07-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE07-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAACACRHQSATGDGAKTFVLLLAAVLGAMREGSPRRAARALPAFERRVLERAVARGLRPHLRSAFPAGGPGEELEAAALEALLEAYLRGRLGPGERRAVTLLGCELCARCGARRPPALRLLCGRFAQLHAAAAGLPLARSRVLPGVLLRRDFAAYCPAGGRLRAVLVTRCLRPVLTGPGVECAVRSERQHRAALRWCGGRTEAVMEHLRSGGVRLLLSGVKQHEEVIFYAKLHGVSVVECLSSEEVALISEIAGISPYDPAGDSVQGEIAEAAVVTFCQPLLLGSQRYVHIGFSSAGAFQPHCLVLCAPVDAINEQHAATLHGAFTMLLQLFRAVDQECGAEGESQNSASGVGSGYSPATETRVVTESIACGSSQVSEHQLGACRGETAAQSSDLALQESERPDGTPPASAPGPHSKELSVCTDGADSAGTHKLPALCECPDGMNESHRRQQAVCSHRNYCTAVASTATLCEHLGVGKGPEKAGYGVTQSCPSSILEAGSVLPVGGYFEILLHYYIQHYAKQVQQSAVTVISNVVADALLSIPKALYGTERNGFTKFYLETTEALRKNQPLPVNEKGLESVYCKYQLVTSVLHCVTELLNIDLIIGVKRPLQKTEDKDSDDDF", "length": 624, "header": "tr|A0A8V0YE07-1|A0A8V0YE07_CHICK Isoform 1 of Bardet-Biedl syndrome 10 OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0YE07-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YE07-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE07/entry#A0A8V0YE07-1", "sequence": { "sequence": "MAACACRHQSATGDGAKTFVLLLAAVLGAMREGSPRRAARALPAFERRVLERAVARGLRPHLRSAFPAGGPGEELEAAALEALLEAYLRGRLGPGERRAVTLLGCELCARCGARRPPALRLLCGRFAQLHAAAAGLPLARSRVLPGVLLRRDFAAYCPAGGRLRAVLVTRCLRPVLTGPGVECAVRSERQHRAALRWCGGRTEAVMEHLRSGGVRLLLSGVKQHEEVIFYAKLHGVSVVECLSSEEVALISEIAGISPYDPAGDSVQGEIAEAAVVTFCQPLLLGSQRYVHIGFSSAGAFQPHCLVLCAPVDAINEQHAATLHGAFTMLLQLFRAVDQECGAEGESQNSASGVGSGYSPATETRVVTESIACGSSQVSEHQLGACRGETAAQSSDLALQESERPDGTPPASAPGPHSKELSVCTDGADSAGTHKLPALCECPDGMNESHRRQQAVCSHRNYCTAVASTATLCEHLGVGKGPEKAGYGVTQSCPSSILEAGSVLPVGGYFEILLHYYIQHYAKQVQQSAVTVISNVVADALLSIPKALYGTERNGFTKFYLETTEALRKNQPLPVNEKGLESVYCKYQLVTSVLHCVTELLNIDLIIGVKRPLQKTEDKDSDDDF", "length": 624, "header": "tr|A0A8V0YE07-1|A0A8V0YE07_CHICK Isoform 1 of Bardet-Biedl syndrome 10 OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0YE07-1" }, "locus": { "chromosome": "1", "start_pos": 38123182, "end_pos": 38122597, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032263.1", "url": "https://www.ensembl.org/id/ENSGALT00010032263.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019053.1", "url": "https://www.ensembl.org/id/ENSGALP00010019053.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "photoreceptor cell maintenance", "id": "GO:0045494", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045494", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YE07", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE07" } ], "pmid": "" }, { "name": "non-motile cilium assembly", "id": "GO:1905515", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905515", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YE07", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE07" } ], "pmid": "" }, { "name": "chaperone-mediated protein complex assembly", "id": "GO:0051131", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051131", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YE07", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE07" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "RNA polymerase II-specific DNA-binding transcription factor binding", "id": "GO:0061629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061629", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YE07", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE07" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 446, "end_pos": 448, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 446, "end_pos": 448 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YE10-1", "uniprot_ac": "A0A8V0YE10", "uniprot_id": "A0A8V0YE10_CHICK", "mass": { "chemical_mass": 85373.0, "monoisotopic_mass": 85373.0 }, "refseq": { "ac": "XP_004938434", "name": "transcription regulator protein BACH1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004938434" }, "gene_names": [ { "name": "BACH1", "type": "recommended", "evidence": [ { "id": "A0A8V0YE10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE10" } ] }, { "name": "BACH1", "type": "synonym", "evidence": [ { "id": "XP_004938434", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004938434" } ] } ], "protein_names": [ { "name": "BTB domain and CNC homolog 1", "type": "synonym", "evidence": [ { "id": "A0A8V0YE10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE10/entry#names_and_taxonomy" } ] }, { "name": "transcription regulator protein BACH1", "type": "synonym", "evidence": [ { "id": "XP_004938434", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004938434" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_004938434.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004938434", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004938434" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YE10", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE10" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "BACH1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE10", "locus": { "chromosome": "1", "start_pos": 104210319, "end_pos": 104182551, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010011622", "url": "https://www.ensembl.org/id/ENSGALG00010011622" } ] } } ], "crossref": [ { "id": "A0A8V0YE10", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YE10", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd14719", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14719", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "418488", "url": "https://www.ncbi.nlm.nih.gov/gene/418488", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000210", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000210", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004826", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004826", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004827", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004827", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008917", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008917", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011333", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011333", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043321", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043321", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046347", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046347", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050457", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050457", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:418488", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418488", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "RRSECPW", "url": "https://omabrowser.org/oma/group/RRSECPW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y5K9", "url": "https://www.orthodb.org/?gene=A0A8V0Y5K9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YAB9", "url": "https://www.orthodb.org/?gene=A0A8V0YAB9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YE10", "url": "https://www.orthodb.org/?gene=A0A8V0YE10", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46105", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46105", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46105:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46105:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00651", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00651", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF03131", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03131", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-9707616", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9707616", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9708530", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9708530", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_004938434", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004938434", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Y5K9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5K9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y5K9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5K9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YAB9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAB9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YAB9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAB9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YE10", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE10", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YE10-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE10-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSLSEKNSVVFAYESSVHSTNVLLSLDDQRKQDILCDVTILVEDQRFRAHKAVLAACSSYFLSRIVGQLDADLIITLPEEVTLKGFSPLLQFAYTAKLILNKDNVSEVCKCAEFLGVRNIEESCFQFLKFKFLDCKSDQECPRKKCCTQHCRKVNPKISSVDDGDLEIDDEAEELIEKEYIQTSHTKLCKDDENAKASPALQDNTNPTSDPMHLEKGNVSSSSSQCPKYRKFQKAFGNDKVHTSDSSSSTKDIQVPPTVTFIEKEIPDNDSTPKAQECVPMQLVSQCEEAQVKMEEGEEDIEKKEESKRDSVTESISCPVEKMDVAAFPQNAAAPHGLNSVSFLRTCEQYGNLNFSSMQSTTILSEKTATGTGAESDKIESHDNATLKVDLCAREAINITSTGDRSSVEREVAEHLAKGFWSDIYSTEACQIHLPSAVPKERLEPAYSGKKSECPWLGIRISESPEPCSQRTFTTLSSVKCPFISNLSTEGCSNSSEISSGDYVQGQQQEQCPYNYVISLGEDSETDTEGDSESCSAREQECEVKLPFNAQRIISLSRNDFQSFLKMHKLTPEQLDCIHDIRRRSKNRIAAQRCRKRKLDCIQNLESEIEKLQNEKENLLKERNLILSTLGETKQNLTGLCQQVCKEAALSNEQIQILAKYSSSDCPLYFSFPERERTAPSEGELTAPTTAELVDGLLSVTPTEEQSSCYQRVKGVCDATYDQVQELHPVPVRTLEKTSLVEQCGQSGAITDFCQQMTDKCTTDE", "length": 765, "header": "tr|A0A8V0YE10-1|A0A8V0YE10_CHICK Isoform 1 of BTB domain and CNC homolog 1 OS=Gallus gallus OX=9031 GN=BACH1 PE=3 SV=1 CANONICAL=A0A8V0YE10-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Y5K9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE10/entry#A0A8V0Y5K9-1", "sequence": { "sequence": "MVYDQRLSGRLFLVNSLGRELKITQKLLASHLEPLKPGGKVTLKGFSPLLQFAYTAKLILNKDNVSEVCKCAEFLGVRNIEESCFQFLKFKFLDCKSDQECPRKKCCTQHCRKVNPKISSVDDGDLEIDDEAEELIEKEYIQTSHTKLCKDDENAKASPALQDNTNPTSDPMHLEKGNVSSSSSQCPKYRKFQKAFGNDKVHTSDSSSSTKDIQVPPTVTFIEKEIPDNDSTPKAQECVPMQLVSQCEEAQVKMEEGEEDIEKKEESKRDSVTESISCPVEKMDVAAFPQNAAAPHGLNSVSFLRTCEQYGNLNFSSMQSTTILSEKTATGTGAESDKIESHDNATLKVDLCAREAINITSTGDRSSVEREVAEHLAKGFWSDIYSTEACQIHLPSAVPKERLEPAYSGKKSECPWLGIRISESPEPCSQRTFTTLSSVKCPFISNLSTEGCSNSSEISSGDYVQGQQQEQCPYNYVISLGEDSETDTEGDSESCSAREQECEVKLPFNAQRIISLSRNDFQSFLKMHKLTPEQLDCIHDIRRRSKNRIAAQRCRKRKLDCIQNLESEIEKLQNEKENLLKERNLILSTLGETKQNLTGLCQQVCKEAALSNEQIQILAKYSSSDCPLYFSFPERERTAPSEGELTAPTTAELVDGLLSVTPTEEQSSCYQRVKGVCDATYDQVQELHPVPVRTLEKTSLVEQCGQSGAITDFCQQMTDKCTTDE", "length": 725, "header": "tr|A0A8V0Y5K9-1|A0A8V0Y5K9_CHICK Computationally mapped isoform of BTB domain and CNC homolog 1 OS=Gallus gallus OX=9031 GN=BACH1 PE=4 SV=1 CANONICAL=A0A8V0YE10-1" }, "locus": { "chromosome": "1", "start_pos": 104208253, "end_pos": 104196203, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027774.1", "url": "https://www.ensembl.org/id/ENSGALT00010027774.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015921.1", "url": "https://www.ensembl.org/id/ENSGALP00010015921.1" } ] } }, { "isoform_ac": "A0A8V0YAB9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE10/entry#A0A8V0YAB9-1", "sequence": { "sequence": "MYFSVSMIRESKIFFVTLKGFSPLLQFAYTAKLILNKDNVSEVCKCAEFLGVRNIEESCFQFLKFKFLDCKSDQECPRKKCCTQHCRKVNPKISSVDDGDLEIDDEAEELIEKEYIQTSHTKLCKDDENAKASPALQDNTNPTSDPMHLEKGNVSSSSSQCPKYRKFQKAFGNDKVHTSDSSSSTKDIQVPPTVTFIEKEIPDNDSTPKAQECVPMQLVSQCEEAQVKMEEGEEDIEKKEESKRDSVTESISCPVEKMDVAAFPQNAAAPHGLNSVSFLRTCEQYGNLNFSSMQSTTILSEKTATGTGAESDKIESHDNATLKVDLCAREAINITSTGDRSSVEREVAEHLAKGFWSDIYSTEACQIHLPSAVPKERLEPAYSGKKSECPWLGIRISESPEPCSQRTFTTLSSVKCPFISNLSTEGCSNSSEISSGDYVQGQQQEQCPYNYVISLGEDSETDTEGDSESCSAREQECEVKLPFNAQRIISLSRNDFQSFLKMHKLTPEQLDCIHDIRRRSKNRIAAQRCRKRKLDCIQNLESEIEKLQNEKENLLKERNLILSTLGETKQNLTGLCQQVCKEAALSNEQIQILAKYSSSDCPLYFSFPERERTAPSEGELTAPTTAELVDGLLSVTPTEEQSSCYQRVKGVCDATYDQVQELHPVPVRTLEKTSLVEQCGQSGAITDFCQQMTDKCTTDE", "length": 700, "header": "tr|A0A8V0YAB9-1|A0A8V0YAB9_CHICK Computationally mapped isoform of BTB domain and CNC homolog 1 OS=Gallus gallus OX=9031 GN=BACH1 PE=4 SV=1 CANONICAL=A0A8V0YE10-1" }, "locus": { "chromosome": "1", "start_pos": 104208253, "end_pos": 104195113, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027782.1", "url": "https://www.ensembl.org/id/ENSGALT00010027782.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015925.1", "url": "https://www.ensembl.org/id/ENSGALP00010015925.1" } ] } }, { "isoform_ac": "A0A8V0YE10-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE10/entry#A0A8V0YE10-1", "sequence": { "sequence": "MSLSEKNSVVFAYESSVHSTNVLLSLDDQRKQDILCDVTILVEDQRFRAHKAVLAACSSYFLSRIVGQLDADLIITLPEEVTLKGFSPLLQFAYTAKLILNKDNVSEVCKCAEFLGVRNIEESCFQFLKFKFLDCKSDQECPRKKCCTQHCRKVNPKISSVDDGDLEIDDEAEELIEKEYIQTSHTKLCKDDENAKASPALQDNTNPTSDPMHLEKGNVSSSSSQCPKYRKFQKAFGNDKVHTSDSSSSTKDIQVPPTVTFIEKEIPDNDSTPKAQECVPMQLVSQCEEAQVKMEEGEEDIEKKEESKRDSVTESISCPVEKMDVAAFPQNAAAPHGLNSVSFLRTCEQYGNLNFSSMQSTTILSEKTATGTGAESDKIESHDNATLKVDLCAREAINITSTGDRSSVEREVAEHLAKGFWSDIYSTEACQIHLPSAVPKERLEPAYSGKKSECPWLGIRISESPEPCSQRTFTTLSSVKCPFISNLSTEGCSNSSEISSGDYVQGQQQEQCPYNYVISLGEDSETDTEGDSESCSAREQECEVKLPFNAQRIISLSRNDFQSFLKMHKLTPEQLDCIHDIRRRSKNRIAAQRCRKRKLDCIQNLESEIEKLQNEKENLLKERNLILSTLGETKQNLTGLCQQVCKEAALSNEQIQILAKYSSSDCPLYFSFPERERTAPSEGELTAPTTAELVDGLLSVTPTEEQSSCYQRVKGVCDATYDQVQELHPVPVRTLEKTSLVEQCGQSGAITDFCQQMTDKCTTDE", "length": 765, "header": "tr|A0A8V0YE10-1|A0A8V0YE10_CHICK Isoform 1 of BTB domain and CNC homolog 1 OS=Gallus gallus OX=9031 GN=BACH1 PE=3 SV=1 CANONICAL=A0A8V0YE10-1" }, "locus": { "chromosome": "1", "start_pos": 104208253, "end_pos": 104195052, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027779.1", "url": "https://www.ensembl.org/id/ENSGALT00010027779.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015924.1", "url": "https://www.ensembl.org/id/ENSGALP00010015924.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:418488", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418488", "resource": "KEGG Pathway" }, { "id": "R-GGA-9707616", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9707616", "resource": "Reactome", "description": "Heme signaling" }, { "id": "R-GGA-9708530", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9708530", "resource": "Reactome", "description": "Regulation of BACH1 activity" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A481CED7-1", "protein_name": "BTB domain and CNC homolog 1", "gene_name": "BACH1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSLGESAVFAYESSVHSAHVLLSLDEQRRKDVLCDVTVLVEGQPFRAHRAVLAACSAYFHARLSGQADAELRITLPEEVTVKGFEPLIQFAYTAKLILSKDNVDEVCKCVEFLGVSDIEESCFQFLKYKFLDSAADQQECPRKKCFSSSCQKPDFKFSLLDQKDLEIDEVEEFLEHKNVRTPHCKLRRYQGSAQVLPPLQDSASQTCESMCLEKDAALSLPSLCPKYRKFQKAFGTDRVRAVESSVKDIHTSSVQPNEPSERECSGGVQDCADLQVILKCEERKLAMEHEEAKKKDPASQCPSEKTGATPFPPSSTDPHGLYSLSLLHTYDQYGDLNFAGMQNTAVLTEKPLSGSDVQEEKTFGESQDLRLKSDSGSREDSSLASSDLSSVEREVAEHLAKGFWTDICSTDSPCQMQLSPAMAKDGSEQIYSQKRSECPWLGIRISESPEPGQRTFTTLSSVNCPFISTLSTEGSSSNLEIGNDDYVSEPQQEPCPYACVISLGDDSETDTEGDSEPCSAREQECEVKLPFNAQRIISLSRNDFQSLLKMHKLTPEQLDCIHDIRRRSKNRIAAQRCRKRKLDCIQNLESEIEKLQNEKESLLKERDHILSTLGETKQNLTGLCQQVCKEAALSQEQIQILAKYSASDCPLSFLVSEKGKSSSDGELVLPSILSLPEGPAAAPPSGEQSPHYPSAKGSEAGQESSATVSAPSEPAGPGEQCRQSGGISDFCQQMTDKCTTDE", "length": 742 }, "evidence": [ { "id": "A0A8V0YE10", "url": "https://omabrowser.org/oma/group/A0A8V0YE10/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "D4ACD2-1", "protein_name": "BTB domain and CNC homolog 1", "gene_name": "Bach1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSVSESAVFAYESSVHSTNVLLSLNDQRKKDVLCDVTVLVEGQQFRAHRSVLAACSSYFHSRIVGQTDAELTITLPQEVTVKGFEPLIQFAYTAKLILSKDNVDEVCKCVEFLSVHNIEESCFQFLKFKFLDSTSEQQGCARKKCFSSHCQKADFKFSFSEQKDLEIDEADEFFEKKSAQTSHCDSQRCQGNVRASPHLQDSVGPTCQSMCVDKDGALALPSLCPKYRKFQKAFGTDKIRTLESGVRDVHAASVHPKETSELECLGGAQGCADLQVILKCEGMKPAMEREDTKCKDPAPQCPAEQAEVTALSQDSAGPHGLYSLSVLHTYEQSGDVGFPGLQSKTVKTEKPLLGPDAQDEKPLENQELYLKSNMGPKEDSSSLASEDRSSVEREVAEHLAKGFWSDICSTDSPCQMQLSSAVAKDGSEQGYSQRRSECPWLGIRISESPEPGQRTFTTLSSVNCPFISTLSSEGCSSNLEIGNYDYVAEPQQEPCPYACVISLGDDSETDTEGDSESCSAREQDCEVKLPFNAQRIISLSRNDFQSLLKMHKLTPEQLDCIHDIRRRSKNRIAAQRCRKRKLDCIQNLESEIEKLQNEKESLLKERDHILSTLGETKQNLTGLCQQVCKEAALSPEQIQILAKYSASDCPLSFLISEKGKSTPDGELPFTSVFSVSDMPPTAPPPCGRGSTAARQELVQESQPTTTATPEQATLLEPCRQSAGISDFCQQMSDKCTTDE", "length": 739 }, "evidence": [ { "id": "A0A8V0YE10", "url": "https://omabrowser.org/oma/group/A0A8V0YE10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E1BJL3-1", "protein_name": "BTB domain and CNC homolog 1", "gene_name": "BACH1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MWLGENAVFAYESSVHGAHVLRCLDEQRRKDELCDVTVLVEGRPFRAHRAVLAACSAYFHARLAGAAGPEPRITLPAEVTVKGFEPLIQFAYTAKLILSKDNVDEVYKCVEFLGVPDIEESCFQFLKYKFLDSTADQQECPRKKCFSSPCQKPDFKFSLLDQKDLEIDEVEEFLDNKNVQTPHCKLRRYQGSAKATPPLQDSASQTCESMCLEKDAALALPSLCPKYRKFQKAFGTDRVRTVESSVKDIQAASVQPHEPSENECLGGIQDCADLQVILKCEERKSAMEHEEAKKKDLASQGSSGKTETTPCPPNSADPHRFYSLSVLHTYDQYGDLNFAGTQNTTVLTEKPSSGSDVREEKAFGESPDVKSDSGPRKESGLAASDLSSVEREVAEHLAKGFWSDVCNTDAPCQMQLSPVVAKDGPEQNYPQKRSECPWLGIRISESPEPGQRTFTTLSSVSCPFISTLSPEGCSSSLEIGTDDYASEPQQEPCPYACVISLGDDSETDTEGDSEPCSAREQECEVKLPFNAQRIISLSRNDFQSLLKMHKLTPEQLDCIHDIRRRSKNRIAAQRCRKRKLDCIQNLESEIEKLQNEKESLLKERDHILSTLGETKQNLTGLCQQVCKEAALSQEQIQILAKYSASDCPLSLLISEKGKSTPDSELALPSILSLSERPAAGLPAGEPSLCYPSTKGGEAGGVRGQESQTATSTLSETREPCRQSGGISDFCQQMTDKCTTDE", "length": 741 }, "evidence": [ { "id": "A0A8V0YE10", "url": "https://omabrowser.org/oma/group/A0A8V0YE10/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "O14867-1", "protein_name": "Transcription regulator protein BACH1", "gene_name": "BACH1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSLSENSVFAYESSVHSTNVLLSLNDQRKKDVLCDVTIFVEGQRFRAHRSVLAACSSYFHSRIVGQADGELNITLPEEVTVKGFEPLIQFAYTAKLILSKENVDEVCKCVEFLSVHNIEESCFQFLKFKFLDSTADQQECPRKKCFSSHCQKTDLKLSLLDQRDLETDEVEEFLENKNVQTPQCKLRRYQGNAKASPPLQDSASQTYESMCLEKDAALALPSLCPKYRKFQKAFGTDRVRTGESSVKDIHASVQPNERSENECLGGVPECRDLQVMLKCDESKLAMEPEETKKDPASQCPTEKSEVTPFPHNSSIDPHGLYSLSLLHTYDQYGDLNFAGMQNTTVLTEKPLSGTDVQEKTFGESQDLPLKSDLGTREDSSVASSDRSSVEREVAEHLAKGFWSDICSTDTPCQMQLSPAVAKDGSEQISQKRSECPWLGIRISESPEPGQRTFTTLSSVNCPFISTLSTEGCSSNLEIGNDDYVSEPQQEPCPYACVISLGDDSETDTEGDSESCSAREQECEVKLPFNAQRIISLSRNDFQSLLKMHKLTPEQLDCIHDIRRRSKNRIAAQRCRKRKLDCIQNLESEIEKLQSEKESLLKERDHILSTLGETKQNLTGLCQKVCKEAALSQEQIQILAKYSAADCPLSFLISEKDKSTPDGELALPSIFSLSDRPPAVLPPCARGNSEPGYARGQESQQMSTATSEQAGPAEQCRQSGGISDFCQQMTDKCTTDE", "length": 736 }, "evidence": [ { "id": "A0A8V0YE10", "url": "https://omabrowser.org/oma/group/A0A8V0YE10/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P97302-1", "protein_name": "Transcription regulator protein BACH1", "gene_name": "Bach1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSVSESAVFAYESSVHSTNVLLSLNDQRKKDVLCDVTVLVEGQRFRAHRSVLAACSSYFHSRIVGQTDAELTVTLPEEVTVKGFEPLIQFAYTAKLILSKDNVDEVCRCVEFLSVHNIEESCFQFLKFKFLDSTSEQQECARKKCFSSHCQKADFKFSFSEQKDLEIDEADEFLEKKRVQTPQCDSRRCQGSVKASPPLQDSVSQACQSLCTDKDGALALPSLCPKYRKFQKAFGTDKIRTLESGVRDVHTASVQPNETSELECFGGAQGCADLHVILKCEGMKAAMESEDTEGQDPSPQCPAEQPQGTPLPQDSAGPHGLYSLSALHTYEQSGDVAFAGVQSKTVKTEKPLSRPDAQDEKPSENQDLYLKSSMGPKEDSSSLASEDRSSVEREVAEHLAKGFWSDICSTDSPCQMQLSPTVAKDGPEQGYSQRRSECPWLGIRISESPEPGQRTFTTLSSVNCPFISTLSSEGCSSNLEIGNYDYVSEPQQEPCPYACVISLGDDSETDTEGDSESCSAREQDCEVKLPFNAQRIISLSRNDFQSLLKMHKLTPEQLDCIHDIRRRSKNRIAAQRCRKRKLDCIQNLESEIEKLQSEKESLLKERDHILSTLGETKQNLTGLCQQVCKEAALSPEQIQILAKYSASDCPLSFLISEKGKSTPDGELAFTSVFSVSDVPPTAPPPCGRGSSAASQELVQESPPTTAAAPEQATLLEPCRQSAGISDFCQQMSDKCTTDE", "length": 739 }, "evidence": [ { "id": "A0A8V0YE10", "url": "https://omabrowser.org/oma/group/A0A8V0YE10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YE10", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE10" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "DNA repair", "id": "GO:0006281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006281", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YE10", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE10" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YE10", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE10" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YE10", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE10" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 7, "go_terms": [ { "name": "DNA-binding transcription repressor activity, RNA polymerase II-specific", "id": "GO:0001227", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001227", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YE10", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE10" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YE10", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE10" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YE10", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE10" } ], "pmid": "" }, { "name": "DNA-binding transcription activator activity, RNA polymerase II-specific", "id": "GO:0001228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001228", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YE10", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE10" } ], "pmid": "" }, { "name": "ligand-modulated transcription factor activity", "id": "GO:0098531", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098531", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YE10", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE10" } ], "pmid": "" }, { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YE10", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE10" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YE10", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE10" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 104, "end_pos": 106, "annotation": "n_glycosylation_sequon" }, { "start_pos": 218, "end_pos": 220, "annotation": "n_glycosylation_sequon" }, { "start_pos": 269, "end_pos": 271, "annotation": "n_glycosylation_sequon" }, { "start_pos": 354, "end_pos": 356, "annotation": "n_glycosylation_sequon" }, { "start_pos": 384, "end_pos": 386, "annotation": "n_glycosylation_sequon" }, { "start_pos": 398, "end_pos": 400, "annotation": "n_glycosylation_sequon" }, { "start_pos": 486, "end_pos": 488, "annotation": "n_glycosylation_sequon" }, { "start_pos": 494, "end_pos": 496, "annotation": "n_glycosylation_sequon" }, { "start_pos": 636, "end_pos": 638, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YE10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE10" }, { "id": "PS50097", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50097" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "BTB", "eco_id": "ECO_0000259", "start_pos": 36, "end_pos": 102, "start_aa": "Cys", "end_aa": "Lys", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0YE10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE10" }, { "id": "PS50217", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50217" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "BZIP", "eco_id": "ECO_0000259", "start_pos": 582, "end_pos": 640, "start_aa": "Arg", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 104, "end_pos": 106 }, { "start_pos": 218, "end_pos": 220 }, { "start_pos": 269, "end_pos": 271 }, { "start_pos": 354, "end_pos": 356 }, { "start_pos": 384, "end_pos": 386 }, { "start_pos": 398, "end_pos": 400 }, { "start_pos": 486, "end_pos": 488 }, { "start_pos": 494, "end_pos": 496 }, { "start_pos": 636, "end_pos": 638 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YE14-1", "uniprot_ac": "A0A8V0YE14", "uniprot_id": "A0A8V0YE14_CHICK", "mass": { "chemical_mass": 91917.0, "monoisotopic_mass": 91917.0 }, "refseq": { "ac": "XP_015145841", "name": "protein AKNAD1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015145841" }, "gene_names": [ { "name": "AKNAD1", "type": "recommended", "evidence": [ { "id": "A0A8V0YE14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE14" } ] }, { "name": "AKNAD1", "type": "synonym", "evidence": [ { "id": "XP_015145841", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015145841" } ] } ], "protein_names": [ { "name": "AKNA domain containing 1", "type": "synonym", "evidence": [ { "id": "A0A8V0YE14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE14/entry#names_and_taxonomy" } ] }, { "name": "protein AKNAD1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015145841", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015145841" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052539.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015145841.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015145841", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015145841" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YE14", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE14" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "AKNAD1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE14", "locus": {} } ], "crossref": [ { "id": "A0A8V0YE14", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YE14", "database": "AlphaFoldDB", "categories": [] }, { "id": "101747831", "url": "https://www.ncbi.nlm.nih.gov/gene/101747831", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR022150", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022150", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052655", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052655", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:101747831", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:101747831", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HCLYINT", "url": "https://omabrowser.org/oma/group/HCLYINT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y7S5", "url": "https://www.orthodb.org/?gene=A0A8V0Y7S5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y7T4", "url": "https://www.orthodb.org/?gene=A0A8V0Y7T4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y7T8", "url": "https://www.orthodb.org/?gene=A0A8V0Y7T8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YE14", "url": "https://www.orthodb.org/?gene=A0A8V0YE14", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YE19", "url": "https://www.orthodb.org/?gene=A0A8V0YE19", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21510", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21510", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21510:SF16", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21510:SF16", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF12443", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12443", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015145841", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015145841", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Y7S5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y7S5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y7S5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y7S5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y7T4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y7T4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y7T4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y7T4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y7T8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y7T8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y7T8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y7T8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YE14", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE14", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YE14-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE14-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YE19", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE19", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YE19-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE19-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEAVRKHRAAEGMEAQTSCSISNELSYVTDTTGAEQDDLPCDGVGGIACEHHDKSDRLHDCICTTRISDTLNLPSSESNRNASANAEIHIQAERVRDCATGTRQTLRISAGAPGSEVSFTQASPAGGNQPHGKDPPCQSNMSHVLLRHFATGELMSTWQLIEHETVPETSLTDSTGKTTNKRETSEHEQQAAKFEEHHLERLKAVDTGGKDQNLLNKNKFLSKTSTYAKCGCRQENSQLINEYEDAHIFQNTEEQKYVFKKSFPSHELIGGHGEVLRGQEDNNEVSSEIQVLKMSENNKSVPTIKRTTSFPTLLNKPVTRNNSLENQNCFDSIEVTYQKETSIPEVSQQRKSGFPNAGFAIYSGDTGTAPESSTADTSVLPQPTRGLSEPRLPCGTTASAFPATRTVEVCSLNASNLLPEITQGEKMSEILKEQTDQLKMKVEDFSKHMTEETLLLQDDYLALNQLKRYLDALERNYLTAREEHRNLQLQHYKDKSINIGEFDPERKVEGEIFRLGTLLEDIQEQADDSKHRWAPSLTSYGSAHSSHSLRESSVLSSVMDSPEENAFLPKNNEGENTSQTSSVIPQKNAHFSLECDRCNLRIHTLQKRAESVYRGEMDPQGESCPLASKHSSNEMRYFSPERKYEAEGLGFHAQGTLSQTYSASEESMKGSTTQERKTGICTIFILRKPADLSDISLKFKCRCSRESQNPFKLRNHKESVQSCAPRRNKNSGSTCYSQKRLPSQKAQTNQQPPKPVNRLSKSKKSARNTSAINIRNRNGKDFNINILNSTLDHAIQTANSLKKATEKMVQTISEDLAKAARTQL", "length": 824, "header": "tr|A0A8V0YE14-1|A0A8V0YE14_CHICK Isoform 1 of AKNA domain containing 1 OS=Gallus gallus OX=9031 GN=AKNAD1 PE=4 SV=1 CANONICAL=A0A8V0YE14-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Y7S5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE14/entry#A0A8V0Y7S5-1", "sequence": { "sequence": "MEAVRKHRAAEGMEAQTSCSISNELSYVTDTTGAEQDDLPCDGVGGIACEHHDKSDRLHDCICTTRISDTLNLPSSESNRNASANAEIHIQAERVRDCATGTRQTLRISAGAPGSEVSFTQASPAGGNQPHGKDPPCQSNMSHVLLRHFATGELMSTWQLIEHETVPETSLTDSTGKTTNKRETSEHEQQAAKFEEHHLERLKAVDTGGKDQNLLNKNKFLSKTSTYAKCGCRQENSQLINEYEDAHIFQNTEEQKYVFKKSFPSHELIGGHGEVLRGQEDNNEVSSEIQVLKMSENNKSVPTIKRTTSFPTLLNKPVTRNNSLENQNCFDSIEVTYQKETSIPEVSQQRKSGFPNAGFAIYSGDTGTAPESSTADTSVLPQPTRGLSEPRLPCGTTASAFPATRTVEVCSLNASNLLPEITQGEKMSEILKEQTDQLKMKVEDFSKHMTEETLLLQDDYLALNQLKRYLDALERNYLTAREEHRNLQLQHYKDKSINIGEFDPERAQSFPVLWILLKKMHFFPRTMKEKIQARQVL", "length": 537, "header": "tr|A0A8V0Y7S5-1|A0A8V0Y7S5_CHICK Computationally mapped isoform of AKNA domain containing 1 OS=Gallus gallus OX=9031 GN=AKNAD1 PE=4 SV=1 CANONICAL=A0A8V0YE14-1" }, "locus": { "chromosome": "8", "start_pos": 1319198, "end_pos": 1314741, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028968.1", "url": "https://www.ensembl.org/id/ENSGALT00010028968.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016727.1", "url": "https://www.ensembl.org/id/ENSGALP00010016727.1" } ] } }, { "isoform_ac": "A0A8V0Y7T4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE14/entry#A0A8V0Y7T4-1", "sequence": { "sequence": "MEAVRKHRAAEGMEAQTSCSISNELSYVTDTTGAEQDDLPCDGVGGIACEHHDKSDRLHDCICTTRISDTLNLPSSESNRNASANAEIHIQAERVRDCATGTRQTLRISAGAPGSEVSFTQASPAGGNQPHGKDPPCQSNMSHVLLRHFATGELMSTWQLIEHETVPETSLTDSTGKTTNKRETSEHEQQAAKFEEHHLERLKAVDTGGKDQNLLNKNKFLSKTSTYAKCGCRQENSQLINEYEDAHIFQNTEEQKYVFKKSFPSHELIGGHGEVLRGQEDNNEVSSEIQVLKMSENNKSVPTIKRTTSFPTLLNKPVTRNNSLENQNCFDSIEVTYQKETSIPEVSQQRKSGFPNAGFAIYSGDTGTAPESSTADTSVLPQPTRGLSEPRLPCGTTASAFPATRTVEVCSLNASNLLPEITQGEKMSEILKEQTDQLKMKVEDFSKHMTEETLLLQDDYLALNQLKRYLDALERNYLTAREEHRNLQLQHYKDKSINIGEFDPERKVEGEIFRLGTLLEDIQEQADDSKHRWAPSLTSYGSAHSSHSLRESSVLSSVMDSPEENAFLPKNNEGENTSQTSSVIPQKNAHFSLECDRCNLRIHTLQKRAESVYRGEMDPQGESCPLASKHSSNEMRYFSPERKYEAEGLGFHAQGTLSQTYSASEESMKGSTTQERKTGICTIFILRKPADLSDISLKFKCRCSRESQNPFKLRNHKESVQSCAPRRNKNSGSTCYSQKRLPSQKAQTNQQPPKPVNRLSKRF", "length": 763, "header": "tr|A0A8V0Y7T4-1|A0A8V0Y7T4_CHICK Computationally mapped isoform of AKNA domain containing 1 OS=Gallus gallus OX=9031 GN=AKNAD1 PE=4 SV=1 CANONICAL=A0A8V0YE14-1" }, "locus": { "chromosome": "8", "start_pos": 1319198, "end_pos": 1308461, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028978.1", "url": "https://www.ensembl.org/id/ENSGALT00010028978.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016737.1", "url": "https://www.ensembl.org/id/ENSGALP00010016737.1" } ] } }, { "isoform_ac": "A0A8V0Y7T8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE14/entry#A0A8V0Y7T8-1", "sequence": { "sequence": "MEAVRKHRAAEGMEAQTSCSISNELSYVTDTTGAEQDDLPCDGVGGIACEHHDKSDRLHDCICTTRISDTLNLPSSESNRNASANAEIHIQAERVRDCATGTRQTLRISAGAPGSEVSFTQASPAGGNQPHGKDPPCQSNMSHVLLRHFATGELMSTWQLIEHETVPETSLTDSTGKTTNKRETSEHEQQAAKFEEHHLERLKAVDTGGKDQNLLNKNKFLSKTSTYAKCGCRQENSQLINEYEDAHIFQNTEEQKYVFKKSFPSHELIGGHGEVLRGQEDNNEVSSEIQVLKMSENNKSVPTIKRTTSFPTLLNKPVTRNNSLENQNCFDSIEVTYQKETSIPEVSQQRKSGFPNAGFAIYSGDTGTAPESSTADTSVLPQPTRGLSEPRLPCGTTASAFPATRTVEVCSLNASNLLPEITQGEKMSEILKEQTDQLKMKVEDFSKHMTEETLLLQDDYLALNQLKRYLDALERNYLTAREEHRNLQLQHYKDKSINIGEFDPERKVEGEIFRLGTLLEDIQEQADDSKHRWAPSLTSYGSAHSSHSLRESSVLSSVMDSPEENAFLPKNNEGENTSQTSSVIPQKNAHFSLECDRCNLRIHTLQKRAESVYRGEMDPQGESCPLASKHSSNEMRYFSPERKYEAEGLGFHAQGTLSQTYSASEESMKGSTTQERKTGICTIFILRKPADLSDISLKFKCRCSRESQNPFKLRNHKESVQSCAPRRNKNSGSTCYSQKRLPSQKAQTNQQPPKPVNRLSKRDFCLRVLK", "length": 770, "header": "tr|A0A8V0Y7T8-1|A0A8V0Y7T8_CHICK Computationally mapped isoform of AKNA domain containing 1 OS=Gallus gallus OX=9031 GN=AKNAD1 PE=4 SV=1 CANONICAL=A0A8V0YE14-1" }, "locus": { "chromosome": "8", "start_pos": 1319198, "end_pos": 1302323, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028983.1", "url": "https://www.ensembl.org/id/ENSGALT00010028983.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016742.1", "url": "https://www.ensembl.org/id/ENSGALP00010016742.1" } ] } }, { "isoform_ac": "A0A8V0YE14-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE14/entry#A0A8V0YE14-1", "sequence": { "sequence": "MEAVRKHRAAEGMEAQTSCSISNELSYVTDTTGAEQDDLPCDGVGGIACEHHDKSDRLHDCICTTRISDTLNLPSSESNRNASANAEIHIQAERVRDCATGTRQTLRISAGAPGSEVSFTQASPAGGNQPHGKDPPCQSNMSHVLLRHFATGELMSTWQLIEHETVPETSLTDSTGKTTNKRETSEHEQQAAKFEEHHLERLKAVDTGGKDQNLLNKNKFLSKTSTYAKCGCRQENSQLINEYEDAHIFQNTEEQKYVFKKSFPSHELIGGHGEVLRGQEDNNEVSSEIQVLKMSENNKSVPTIKRTTSFPTLLNKPVTRNNSLENQNCFDSIEVTYQKETSIPEVSQQRKSGFPNAGFAIYSGDTGTAPESSTADTSVLPQPTRGLSEPRLPCGTTASAFPATRTVEVCSLNASNLLPEITQGEKMSEILKEQTDQLKMKVEDFSKHMTEETLLLQDDYLALNQLKRYLDALERNYLTAREEHRNLQLQHYKDKSINIGEFDPERKVEGEIFRLGTLLEDIQEQADDSKHRWAPSLTSYGSAHSSHSLRESSVLSSVMDSPEENAFLPKNNEGENTSQTSSVIPQKNAHFSLECDRCNLRIHTLQKRAESVYRGEMDPQGESCPLASKHSSNEMRYFSPERKYEAEGLGFHAQGTLSQTYSASEESMKGSTTQERKTGICTIFILRKPADLSDISLKFKCRCSRESQNPFKLRNHKESVQSCAPRRNKNSGSTCYSQKRLPSQKAQTNQQPPKPVNRLSKSKKSARNTSAINIRNRNGKDFNINILNSTLDHAIQTANSLKKATEKMVQTISEDLAKAARTQL", "length": 824, "header": "tr|A0A8V0YE14-1|A0A8V0YE14_CHICK Isoform 1 of AKNA domain containing 1 OS=Gallus gallus OX=9031 GN=AKNAD1 PE=4 SV=1 CANONICAL=A0A8V0YE14-1" }, "locus": { "chromosome": "8", "start_pos": 1319198, "end_pos": 1308348, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028975.1", "url": "https://www.ensembl.org/id/ENSGALT00010028975.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016734.1", "url": "https://www.ensembl.org/id/ENSGALP00010016734.1" } ] } }, { "isoform_ac": "A0A8V0YE19-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE14/entry#A0A8V0YE19-1", "sequence": { "sequence": "MEAVRKHRAAEGMEAQTSCSISNELSYVTDTTGAEQDDLPCDGVGGIACEHHDKSDRLHDCICTTRISDTLNLPSSESNRNASANAEIHIQAERVRDCATGTRQTLRISAGAPGSEVSFTQASPAGGNQPHGKDPPCQSNMSHVLLRHFATGELMSTWQLIEHETVPETSLTDSTGKTTNKRETSEHEQQAAKFEEHHLERLKAVDTGGKDQNLLNKNKFLSKTSTYAKCGCRQENSQLINEYEDAHIFQNTEEQKYVFKKSFPSHELIGGHGEVLRGQEDNNEVSSEIQVLKMSENNKSVPTIKRTTSFPTLLNKPVTRNNSLENQNCFDSIEVTYQKETSIPEVSQQRKSGFPNAGFAIYSGDTGTAPESSTADTSVLPQPTRGLSEPRLPCGTTASAFPATRTVEVCSLNASNLLPEITQGEKMSEILKEQTDQLKMKVEDFSKHMTEETLLLQDDYLALNQLKRYLDALERNYLTAREEHRNLQLQHYKDKSINIGEFDPERKVEGEIFRLGTLLEDIQEQADDSKHRWAPSLTSYGSAHSSHSLRESSVLSSVMDSPEENAFLPKNNEGENTSQTSSVIPQKNAHFSLECDRCNLRIHTLQKRAESVYRGEMDPQGESCPLASKHSSNEMRYFSPERKYEAEGLGFHAQGTLSQTYSASEESMKGSTTQERKTGICTIFILRKPADLSDISLKFKCRCSRESQNPFKLRNHKESVQSCAPRRNKNSGSTCYSQKRLPSQKAQTNQQPPKPVNRLSKSKKSARNTSAINIRNRNGKDFNINPHFTYSKAATRPLSSPG", "length": 802, "header": "tr|A0A8V0YE19-1|A0A8V0YE19_CHICK Computationally mapped isoform of AKNA domain containing 1 OS=Gallus gallus OX=9031 GN=AKNAD1 PE=4 SV=1 CANONICAL=A0A8V0YE14-1" }, "locus": { "chromosome": "8", "start_pos": 1319198, "end_pos": 1307169, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028980.1", "url": "https://www.ensembl.org/id/ENSGALT00010028980.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016739.1", "url": "https://www.ensembl.org/id/ENSGALP00010016739.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:101747831", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:101747831", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 140, "end_pos": 142, "annotation": "n_glycosylation_sequon" }, { "start_pos": 298, "end_pos": 300, "annotation": "n_glycosylation_sequon" }, { "start_pos": 321, "end_pos": 323, "annotation": "n_glycosylation_sequon" }, { "start_pos": 413, "end_pos": 415, "annotation": "n_glycosylation_sequon" }, { "start_pos": 576, "end_pos": 578, "annotation": "n_glycosylation_sequon" }, { "start_pos": 768, "end_pos": 770, "annotation": "n_glycosylation_sequon" }, { "start_pos": 788, "end_pos": 790, "annotation": "n_glycosylation_sequon" }, { "start_pos": 81, "end_pos": 83, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YE14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE14" }, { "id": "PF12443", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12443" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "AKNA", "eco_id": "ECO_0000259", "start_pos": 406, "end_pos": 466, "start_aa": "Thr", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 140, "end_pos": 142 }, { "start_pos": 298, "end_pos": 300 }, { "start_pos": 321, "end_pos": 323 }, { "start_pos": 413, "end_pos": 415 }, { "start_pos": 576, "end_pos": 578 }, { "start_pos": 768, "end_pos": 770 }, { "start_pos": 788, "end_pos": 790 }, { "start_pos": 81, "end_pos": 83 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YE32-1", "uniprot_ac": "A0A8V0YE32", "uniprot_id": "A0A8V0YE32_CHICK", "mass": { "chemical_mass": 60199.0, "monoisotopic_mass": 60199.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "RNase H type-1 domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A8V0YE32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE32/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YE32", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE32" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE32", "locus": {} } ], "crossref": [ { "id": "A0A8V0YE32", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YE32", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR002156", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002156", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012337", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012337", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036397", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036397", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041577", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041577", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043128", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043128", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043502", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043502", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051320", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051320", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR33064", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR33064", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR33064:SF29", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR33064:SF29", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00075", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00075", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17919", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17919", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YE32", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE32", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YE32-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE32-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSPPINKKETQSFLGVVGFWRMHVPNYSLIVSPLYQVTRKKNDFTWGPEQQQAFEQIKHEIARAVALGPVRTGQDVKNILYTAAGEKGPTWSLWQRTSGETRGRPLGFWSRAYRGSEECYTPTEKEILAAYEGVRAASEVVGTETQLLLAPRLPVLNWMFKGQIPSTHHATDATWSKWIALITQRARMGNFSLPGILEVIMDWPEGKKFETSPGEEVSRAKEAPPYNELPGNEKKYALFTDGSCRIVGKYRRWKAAVWSPVRQVAEATEGKGESSQFAEVKAVQLALDVAEREGWPVLYLYTDSWMVANALWGWLQQWEQNNWQRRGKPIWSAELWKDIAARIKNMVVKVRHVDAHVPKSRATEEQKNNHHVDQAAKIEVAQIDLDWQNKGELFLARWAHETSGHQGRDATYKWARDRGVDLTMDAIAQVIHDCETCAIIKQAKRMKPLWEEGRWQKYKYGEAWQIDYITLPRSCNEKNYVSQRTSRSEKEDTSRKIRHLVARGASSLSLAAGRGVGVLSKPGAFIKP", "length": 528, "header": "tr|A0A8V0YE32-1|A0A8V0YE32_CHICK Isoform 1 of RNase H type-1 domain-containing protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0YE32-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YE32-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE32/entry#A0A8V0YE32-1", "sequence": { "sequence": "MSPPINKKETQSFLGVVGFWRMHVPNYSLIVSPLYQVTRKKNDFTWGPEQQQAFEQIKHEIARAVALGPVRTGQDVKNILYTAAGEKGPTWSLWQRTSGETRGRPLGFWSRAYRGSEECYTPTEKEILAAYEGVRAASEVVGTETQLLLAPRLPVLNWMFKGQIPSTHHATDATWSKWIALITQRARMGNFSLPGILEVIMDWPEGKKFETSPGEEVSRAKEAPPYNELPGNEKKYALFTDGSCRIVGKYRRWKAAVWSPVRQVAEATEGKGESSQFAEVKAVQLALDVAEREGWPVLYLYTDSWMVANALWGWLQQWEQNNWQRRGKPIWSAELWKDIAARIKNMVVKVRHVDAHVPKSRATEEQKNNHHVDQAAKIEVAQIDLDWQNKGELFLARWAHETSGHQGRDATYKWARDRGVDLTMDAIAQVIHDCETCAIIKQAKRMKPLWEEGRWQKYKYGEAWQIDYITLPRSCNEKNYVSQRTSRSEKEDTSRKIRHLVARGASSLSLAAGRGVGVLSKPGAFIKP", "length": 528, "header": "tr|A0A8V0YE32-1|A0A8V0YE32_CHICK Isoform 1 of RNase H type-1 domain-containing protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0YE32-1" }, "locus": { "chromosome": "3", "start_pos": 64835236, "end_pos": 64821572, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032288.1", "url": "https://www.ensembl.org/id/ENSGALT00010032288.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019078.1", "url": "https://www.ensembl.org/id/ENSGALP00010019078.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "nucleic acid binding", "id": "GO:0003676", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003676", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YE32", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE32" } ], "pmid": "" }, { "name": "RNA-DNA hybrid ribonuclease activity", "id": "GO:0004523", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004523", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YE32", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE32" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "DNA metabolic process", "id": "GO:0006259", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006259", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YE32", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE32" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 190, "end_pos": 192, "annotation": "n_glycosylation_sequon" }, { "start_pos": 26, "end_pos": 28, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YE32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE32" }, { "id": "PS50879", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50879" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RNase H type-1", "eco_id": "ECO_0000259", "start_pos": 232, "end_pos": 381, "start_aa": "Asn", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 190, "end_pos": 192 }, { "start_pos": 26, "end_pos": 28 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YE35-1", "uniprot_ac": "A0A8V0YE35", "uniprot_id": "A0A8V0YE35_CHICK", "mass": { "chemical_mass": 109820.0, "monoisotopic_mass": 109820.0 }, "refseq": { "ac": "XP_025007665", "name": "multimerin-2 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025007665" }, "gene_names": [ { "name": "MMRN2", "type": "recommended", "evidence": [ { "id": "A0A8V0YE35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE35" } ] }, { "name": "MMRN2", "type": "synonym", "evidence": [ { "id": "XP_025007665", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025007665" } ] } ], "protein_names": [ { "name": "Multimerin 2", "type": "synonym", "evidence": [ { "id": "A0A8V0YE35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE35/entry#names_and_taxonomy" } ] }, { "name": "multimerin-2 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_025007665", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025007665" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052537.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_025007665.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_025007665", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025007665" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YE35", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE35" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MMRN2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE35", "locus": { "chromosome": "6", "start_pos": 3288300, "end_pos": 3307156, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010010472", "url": "https://www.ensembl.org/id/ENSGALG00010010472" } ] } } ], "crossref": [ { "id": "A0A8V0YE35", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YE35", "database": "AlphaFoldDB", "categories": [] }, { "id": "423611", "url": "https://www.ncbi.nlm.nih.gov/gene/423611", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001073", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001073", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008983", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008983", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011489", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011489", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050392", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050392", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:423611", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423611", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YE35", "url": "https://www.orthodb.org/?gene=A0A8V0YE35", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15427", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15427", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15427:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15427:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00386", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00386", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07546", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07546", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_025007665", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025007665", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YE35", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE35", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YE35-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE35-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLVKVLLICNTIGLAKLARHVDHHGYHSAPMHGSKAQSHETPTDPERALLQEEEGSWEAAGRRADVPDYPVSIAYPHQGEREQLEAASPPSRNGNWCSFMQSRLVTYIEACMKEKYIINSQQPCPNGAPACQRIMYRTALKPVYQVKQKVLKSLQWKCCPGFIGKDCEQRDPNVIPVPGNHTKGRQEEEFSNHNFQERLLRQVLFPHVENFLRKHLNPVWASFNRSLQNLSNIVRNLSHDVEANKKSIERFQESTVPKKEFQELGTKFESKVQENAVKVDQIRRDIENQLQMQQASIQHNLTIIRADTDTRLKKHHKIQQSHHLALNNNVTDLQHEQNNLENKFETLKKSLTELSSHHGPKDETTQLAIRQINDMLAGHAKQLKDLYMESDVAFQNIAVLERWFKELKKNISKYRPEDLSITLMEKSVLIEENKAAMERQISEMNDTLSNLQENYSDLLRYMEECNCQKIPSDANTLEEDLKNITYSLEGQQSKDVKQLESVFKDLLRNEIEELSSAFPFIHQSLNLRQEENRQLQLQVASFSEDIGLLKKKDEEIHRHIKYLNSSFGSLLEDAMRHEAALEALLGEEFMEVLFEEDPSTLISSVVQLQEFLKEISNKLQNQNVTLESLVKRLHHLERGQQNNHHVHASSKRPEQETQTLSMLDEANQLSSVEHTEPNYEASKDESLHSSTYNDIMTLKNDIKYLSLAIKRHESRNDMSVCCNHTIANVVEPLNVSVEIISGDLATMKEKLEKHLLIFKKLFGSDEELLASNISLDVAKIQSMLTRKVRRQEKGQDKQRDKKRPEKQRENTQIVSGRNRVQTELLEKDSSVAFHVGFSDRKDKEKALRFNETYLNYGNSYFPEHGYFKAPHKGVYLFVISVEFSSGPALGQLSFSSGYKRTLSSSQRKTPNGHTVTSFAMAEMEKGEKVCFELLQGTVVKRSPPGTTMGGFLLFKT", "length": 956, "header": "tr|A0A8V0YE35-1|A0A8V0YE35_CHICK Isoform 1 of Multimerin 2 OS=Gallus gallus OX=9031 GN=MMRN2 PE=1 SV=1 CANONICAL=A0A8V0YE35-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YE35-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE35/entry#A0A8V0YE35-1", "sequence": { "sequence": "MLVKVLLICNTIGLAKLARHVDHHGYHSAPMHGSKAQSHETPTDPERALLQEEEGSWEAAGRRADVPDYPVSIAYPHQGEREQLEAASPPSRNGNWCSFMQSRLVTYIEACMKEKYIINSQQPCPNGAPACQRIMYRTALKPVYQVKQKVLKSLQWKCCPGFIGKDCEQRDPNVIPVPGNHTKGRQEEEFSNHNFQERLLRQVLFPHVENFLRKHLNPVWASFNRSLQNLSNIVRNLSHDVEANKKSIERFQESTVPKKEFQELGTKFESKVQENAVKVDQIRRDIENQLQMQQASIQHNLTIIRADTDTRLKKHHKIQQSHHLALNNNVTDLQHEQNNLENKFETLKKSLTELSSHHGPKDETTQLAIRQINDMLAGHAKQLKDLYMESDVAFQNIAVLERWFKELKKNISKYRPEDLSITLMEKSVLIEENKAAMERQISEMNDTLSNLQENYSDLLRYMEECNCQKIPSDANTLEEDLKNITYSLEGQQSKDVKQLESVFKDLLRNEIEELSSAFPFIHQSLNLRQEENRQLQLQVASFSEDIGLLKKKDEEIHRHIKYLNSSFGSLLEDAMRHEAALEALLGEEFMEVLFEEDPSTLISSVVQLQEFLKEISNKLQNQNVTLESLVKRLHHLERGQQNNHHVHASSKRPEQETQTLSMLDEANQLSSVEHTEPNYEASKDESLHSSTYNDIMTLKNDIKYLSLAIKRHESRNDMSVCCNHTIANVVEPLNVSVEIISGDLATMKEKLEKHLLIFKKLFGSDEELLASNISLDVAKIQSMLTRKVRRQEKGQDKQRDKKRPEKQRENTQIVSGRNRVQTELLEKDSSVAFHVGFSDRKDKEKALRFNETYLNYGNSYFPEHGYFKAPHKGVYLFVISVEFSSGPALGQLSFSSGYKRTLSSSQRKTPNGHTVTSFAMAEMEKGEKVCFELLQGTVVKRSPPGTTMGGFLLFKT", "length": 956, "header": "tr|A0A8V0YE35-1|A0A8V0YE35_CHICK Isoform 1 of Multimerin 2 OS=Gallus gallus OX=9031 GN=MMRN2 PE=1 SV=1 CANONICAL=A0A8V0YE35-1" }, "locus": { "chromosome": "6", "start_pos": 3307091, "end_pos": 3288500, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010025026.1", "url": "https://www.ensembl.org/id/ENSGALT00010025026.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010014225.1", "url": "https://www.ensembl.org/id/ENSGALP00010014225.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:423611", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423611", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "negative regulation of cell migration involved in sprouting angiogenesis", "id": "GO:0090051", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090051", 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Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_004934573.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004934573", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004934573" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YE42", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE42" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SON", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE42", "locus": { "chromosome": "1", "start_pos": 105525594, "end_pos": 105494869, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012102", "url": "https://www.ensembl.org/id/ENSGALG00010012102" } ] } } ], "crossref": [ { "id": "770637", "url": "https://www.ncbi.nlm.nih.gov/gene/770637", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000467", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000467", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014720", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014720", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032922", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032922", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YE42", "url": "https://www.orthodb.org/?gene=A0A8V0YE42", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46528", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46528", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46528:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46528:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01585", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01585", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14709", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14709", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17069", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17069", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_004934573", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004934573", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YE42", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE42", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YE42-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE42-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MMQRNKKGVDLSPSPGLGSGKKKSRSRSTSRRLTSKRARSRSRNYSDSRKKHSKSRSRSVEKRERRVSSRRSRRRRSRSSDRYRSKSRSVEKTRRSVRGRSRSSDRYRSKSRSVEKRESRLSSRRSRRRRSRSSDRYRSKSRSAEKRGSRLSSRRSRRGRSRSSDRYRSKSRSVEKTRRSGRRRSRSSDRYRSKSRSVEKTRRSGRRRSRSSDRYRSKSRSVEKTRRSGRRRSRSSDRYRSKSPSVEKRGSRLSSWRSRRRRSRSSDHSKSRSRSSEKRGGKEYSWRFRHRGSGSSDRSKSRSRSVEKRGRKASLRRSKRRRSKSSDHYKSRSRSVEKRDRKQSSRKSKRQRSKSSDRYKSRSKSVEKKKESSRKSKRRRSKSSERYKSRSRSVEKKRKESSKKSKRKRSKSSDSLKSRSKSVEKRASKLASAKCSRKHADSSEQEKVDGSEPVTSEISSSKSSNGPVSVALSLEGVNGPELPPPSGSGFSTVESLETSSSVEKMDGPQPSVIPELDSSKTSNDQEQCSLPVEKTQVSVTSENGSATLYDSDLGSVPVEKTVPLESSSPTELTFPASSSVSSSVEKRDPETTSLTEFHLSASHQDESRSTSLKKVEGPEPLLTNESGCSVSADDYKSTSTSSGNMEIQGFSLTSGSVLSDVHELRHIPAENAEPQKFLQVPQSGSSELADSTESRSLSFETTEVQKPFLAPEVTSSEFLDVHDSASLPIARGQMEMPSLASDSVCFRTPDRHELGSSFGTQIEELPLISEGASLQSPVGKVKAPSAFLTSECGPVEITVDHISTSSSPKVQEVFLTTVGQSCTSSEAHESSSSVDKDLGGSASSQVLGVGCFETSEVNESRHLPAEKIEVTESALSKSGIPLCHHGHESEYSYFEKTKGVDMVESVSTPAEKLEATVPCLTSEGGLFMLPDSHELRATHTDAVEVQKSSLPSEQKCIASADEHQLRSPSGREIQVQEEQPLIVESRHSVSSGDYELTLTPFKKADVGDPSQMPGNEYTVGLPGPELMTSSAEKTEVQELNVIPEERCSVSLESQELLSPAFEKTEVQEPALTSENEYTVSWKCQELRASSPEKVEMQKPFIVPDSECAAYSGDQESQTLPAEKSEVQMHSSMSENEYAASPEGQDMTAISAETVQEPSAVSCREYVAVPTGQDLSSLPEKTEVQECSVLSENEYDISPEGHDLRSSPAKGEMREPSETSESESSMSTDDQELQSTAVGKTEVQELSLMSEGECAMSPEVQELQSSPAEKVETEEPSLTHENEHAVSLEGYESRSTRGDKTEDTDSSLTSERDHYLSFKSQEVRFTTVQKVDVQELSPTSESEHTASPDSQELRFLTAGQVGDSEPLTLNDRGSMSPDVSDLKSIAVEKMDDATPLMPESGCSVSPGGNSMKSVPGEETGDLETSLASECRHSISPYHESHEVKSPIEEDGLESSDTFEHRRSVTPEGHDEKSVIDEEMEDREPSLTSEHRRSTSPDEHESRSSIGEEAEYSEQPLTMERRSSISSDEHDSRSTAGEEVEDVEPSLTGKRRDSTSSDERDSRSTTGEEAEDHETLAAERRDSVSSDERDSRSTAGEEVEDLEPLAAGHRRSVSPDGRESRSTTGEEAEDREPSLTAERRHSTSSDERESRSTTGEDVEDVEPSLTAERRDSTSSDEQDSRSTTGEEAEDMELSLTTEHRHSTSPDGRESRSTTGEEGEDVEPSLTAERRDSTSSDDHESRSTTGEEVEDMEPSLAVEDKHEGSPSIPLEKSEGQDSSFMTESRRSESSEREKSRSESAEKMSDRESSQRSRSRPSKSPTHQMSRSPSVDKAADEESSRRSRHRRSRSTSVEKAADKESSRRSRHRRSRSAARQMSRSVSVEKTADKESSRRSRRRRSRSAARQRSRSKSVDKTADKESSRRSRSRRSRSSQRRSQRYDADSRSRRNRSRSVTRRRASRSKSNRRSRSSSLSRSRHRRRSRSRSASRRRRSLSRDRRRRSQRNRSRSADRRRRRSDSRDRRISLRLRSRSRTPLRQRRSRSRGRRRSSSRSPIRLRRSRSSGRRRGYSRSPDRRRSRSSERFSSRSPKRLTDLDKAQLLEIAKANAAAMCAKSGVPLPPSLMPMLSQKKDDKASQKSSRDTLKELTEKCKKIAQSTDDVIVNKPHVSDEEEEERPFYNHPFKLNEPKPIFFNLSTPSIKPAPPPQPKNQVSLSKEFPVSSGSQHRKKEADSVYGEWVPVEKGKEDSKDDVFPKPSIEGVDITAAMNDRALAQKRLNENTFDLEAMCMLNRAQEQIDAWAQSNSIPGQFTGSTGAQILSSDELTNSGPQAWIRKDQFLRAAPVTGGMGAQLMRKMGWREGEGLGKNKEGSVEPIMVDFKTDRKGLVAVGEKAQKRSGHYVVMKDLSGKHPVSALMEICNKRRWSPPEFVLVDDSGPDHRKHFIFKRWLGYAGQCLNANVSESCFCESQIRSLQRINLQIHQETVIPFHGLLK", "length": 2489, "header": "tr|A0A8V0YE42-1|A0A8V0YE42_CHICK Isoform 1 of SON DNA and RNA binding protein OS=Gallus gallus OX=9031 GN=SON PE=1 SV=1 CANONICAL=A0A8V0YE42-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YE42-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE42/entry#A0A8V0YE42-1", "sequence": { "sequence": "MMQRNKKGVDLSPSPGLGSGKKKSRSRSTSRRLTSKRARSRSRNYSDSRKKHSKSRSRSVEKRERRVSSRRSRRRRSRSSDRYRSKSRSVEKTRRSVRGRSRSSDRYRSKSRSVEKRESRLSSRRSRRRRSRSSDRYRSKSRSAEKRGSRLSSRRSRRGRSRSSDRYRSKSRSVEKTRRSGRRRSRSSDRYRSKSRSVEKTRRSGRRRSRSSDRYRSKSRSVEKTRRSGRRRSRSSDRYRSKSPSVEKRGSRLSSWRSRRRRSRSSDHSKSRSRSSEKRGGKEYSWRFRHRGSGSSDRSKSRSRSVEKRGRKASLRRSKRRRSKSSDHYKSRSRSVEKRDRKQSSRKSKRQRSKSSDRYKSRSKSVEKKKESSRKSKRRRSKSSERYKSRSRSVEKKRKESSKKSKRKRSKSSDSLKSRSKSVEKRASKLASAKCSRKHADSSEQEKVDGSEPVTSEISSSKSSNGPVSVALSLEGVNGPELPPPSGSGFSTVESLETSSSVEKMDGPQPSVIPELDSSKTSNDQEQCSLPVEKTQVSVTSENGSATLYDSDLGSVPVEKTVPLESSSPTELTFPASSSVSSSVEKRDPETTSLTEFHLSASHQDESRSTSLKKVEGPEPLLTNESGCSVSADDYKSTSTSSGNMEIQGFSLTSGSVLSDVHELRHIPAENAEPQKFLQVPQSGSSELADSTESRSLSFETTEVQKPFLAPEVTSSEFLDVHDSASLPIARGQMEMPSLASDSVCFRTPDRHELGSSFGTQIEELPLISEGASLQSPVGKVKAPSAFLTSECGPVEITVDHISTSSSPKVQEVFLTTVGQSCTSSEAHESSSSVDKDLGGSASSQVLGVGCFETSEVNESRHLPAEKIEVTESALSKSGIPLCHHGHESEYSYFEKTKGVDMVESVSTPAEKLEATVPCLTSEGGLFMLPDSHELRATHTDAVEVQKSSLPSEQKCIASADEHQLRSPSGREIQVQEEQPLIVESRHSVSSGDYELTLTPFKKADVGDPSQMPGNEYTVGLPGPELMTSSAEKTEVQELNVIPEERCSVSLESQELLSPAFEKTEVQEPALTSENEYTVSWKCQELRASSPEKVEMQKPFIVPDSECAAYSGDQESQTLPAEKSEVQMHSSMSENEYAASPEGQDMTAISAETVQEPSAVSCREYVAVPTGQDLSSLPEKTEVQECSVLSENEYDISPEGHDLRSSPAKGEMREPSETSESESSMSTDDQELQSTAVGKTEVQELSLMSEGECAMSPEVQELQSSPAEKVETEEPSLTHENEHAVSLEGYESRSTRGDKTEDTDSSLTSERDHYLSFKSQEVRFTTVQKVDVQELSPTSESEHTASPDSQELRFLTAGQVGDSEPLTLNDRGSMSPDVSDLKSIAVEKMDDATPLMPESGCSVSPGGNSMKSVPGEETGDLETSLASECRHSISPYHESHEVKSPIEEDGLESSDTFEHRRSVTPEGHDEKSVIDEEMEDREPSLTSEHRRSTSPDEHESRSSIGEEAEYSEQPLTMERRSSISSDEHDSRSTAGEEVEDVEPSLTGKRRDSTSSDERDSRSTTGEEAEDHETLAAERRDSVSSDERDSRSTAGEEVEDLEPLAAGHRRSVSPDGRESRSTTGEEAEDREPSLTAERRHSTSSDERESRSTTGEDVEDVEPSLTAERRDSTSSDEQDSRSTTGEEAEDMELSLTTEHRHSTSPDGRESRSTTGEEGEDVEPSLTAERRDSTSSDDHESRSTTGEEVEDMEPSLAVEDKHEGSPSIPLEKSEGQDSSFMTESRRSESSEREKSRSESAEKMSDRESSQRSRSRPSKSPTHQMSRSPSVDKAADEESSRRSRHRRSRSTSVEKAADKESSRRSRHRRSRSAARQMSRSVSVEKTADKESSRRSRRRRSRSAARQRSRSKSVDKTADKESSRRSRSRRSRSSQRRSQRYDADSRSRRNRSRSVTRRRASRSKSNRRSRSSSLSRSRHRRRSRSRSASRRRRSLSRDRRRRSQRNRSRSADRRRRRSDSRDRRISLRLRSRSRTPLRQRRSRSRGRRRSSSRSPIRLRRSRSSGRRRGYSRSPDRRRSRSSERFSSRSPKRLTDLDKAQLLEIAKANAAAMCAKSGVPLPPSLMPMLSQKKDDKASQKSSRDTLKELTEKCKKIAQSTDDVIVNKPHVSDEEEEERPFYNHPFKLNEPKPIFFNLSTPSIKPAPPPQPKNQVSLSKEFPVSSGSQHRKKEADSVYGEWVPVEKGKEDSKDDVFPKPSIEGVDITAAMNDRALAQKRLNENTFDLEAMCMLNRAQEQIDAWAQSNSIPGQFTGSTGAQILSSDELTNSGPQAWIRKDQFLRAAPVTGGMGAQLMRKMGWREGEGLGKNKEGSVEPIMVDFKTDRKGLVAVGEKAQKRSGHYVVMKDLSGKHPVSALMEICNKRRWSPPEFVLVDDSGPDHRKHFIFKRWLGYAGQCLNANVSESCFCESQIRSLQRINLQIHQETVIPFHGLLK", "length": 2489, "header": "tr|A0A8V0YE42-1|A0A8V0YE42_CHICK Isoform 1 of SON DNA and RNA binding protein OS=Gallus gallus OX=9031 GN=SON PE=1 SV=1 CANONICAL=A0A8V0YE42-1" }, "locus": { "chromosome": "1", "start_pos": 105523453, "end_pos": 105495068, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029005.1", "url": "https://www.ensembl.org/id/ENSGALT00010029005.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016764.1", "url": "https://www.ensembl.org/id/ENSGALP00010016764.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YE42", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE42" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "regulation of mRNA splicing, via spliceosome", "id": "GO:0048024", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048024", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YE42", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE42" } ], "pmid": "" }, { "name": "regulation of cell cycle", "id": "GO:0051726", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051726", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YE42", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE42" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1945, "end_pos": 1947, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2001, "end_pos": 2003, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2190, "end_pos": 2192, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2455, "end_pos": 2457, "annotation": "n_glycosylation_sequon" }, { "start_pos": 44, "end_pos": 46, "annotation": "n_glycosylation_sequon" }, { "start_pos": 543, "end_pos": 545, "annotation": "n_glycosylation_sequon" }, { "start_pos": 624, "end_pos": 626, "annotation": "n_glycosylation_sequon" }, { "start_pos": 858, "end_pos": 860, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YE42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE42" }, { "id": "PS50137", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50137" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "DRBM", "eco_id": "ECO_0000259", "start_pos": 2406, "end_pos": 2442, "start_aa": "His", "end_aa": "Lys", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0YE42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE42" }, { "id": "PS50174", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50174" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-patch", "eco_id": "ECO_0000259", "start_pos": 2341, "end_pos": 2387, "start_aa": "Thr", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1945, "end_pos": 1947 }, { "start_pos": 2001, "end_pos": 2003 }, { "start_pos": 2190, "end_pos": 2192 }, { "start_pos": 2455, "end_pos": 2457 }, { "start_pos": 44, "end_pos": 46 }, { "start_pos": 543, "end_pos": 545 }, { "start_pos": 624, "end_pos": 626 }, { "start_pos": 858, "end_pos": 860 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YE46-1", "uniprot_ac": "A0A8V0YE46", "uniprot_id": "A0A8V0YE46_CHICK", "mass": { "chemical_mass": 153448.0, "monoisotopic_mass": 153448.0 }, "refseq": {}, "gene_names": [ { "name": "KIAA0825", "type": "recommended", "evidence": [ { "id": "A0A8V0YE46", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE46" } ] } ], "protein_names": [ { "name": "KIAA0825", "type": "synonym", "evidence": [ { "id": "A0A8V0YE46", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE46/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YE46", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE46" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "KIAA0825", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE46", "locus": { "chromosome": "Z", "start_pos": 58897187, "end_pos": 58665367, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013410", "url": "https://www.ensembl.org/id/ENSGALG00010013410" } ] } } ], "crossref": [ { "id": "427110", "url": "https://www.ncbi.nlm.nih.gov/gene/427110", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR027993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YE46", "url": "https://www.orthodb.org/?gene=A0A8V0YE46", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YE52", "url": "https://www.orthodb.org/?gene=A0A8V0YE52", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YE57", "url": "https://www.orthodb.org/?gene=A0A8V0YE57", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YJT8", "url": "https://www.orthodb.org/?gene=A0A8V0YJT8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YJW9", "url": "https://www.orthodb.org/?gene=A0A8V0YJW9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YKG9", "url": "https://www.orthodb.org/?gene=A0A8V0YKG9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YKJ4", "url": "https://www.orthodb.org/?gene=A0A8V0YKJ4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YME4", "url": "https://www.orthodb.org/?gene=A0A8V0YME4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YME8", "url": "https://www.orthodb.org/?gene=A0A8V0YME8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YSB8", "url": "https://www.orthodb.org/?gene=A0A8V0YSB8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR33960", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR33960", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR33960:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR33960:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF14906", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14906", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YE46", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE46", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YE46-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE46-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YE52", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE52", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YE52-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE52-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YE57", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE57", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YE57-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE57-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJT8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJT8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJT8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJT8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJW9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJW9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJW9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJW9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YKG9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKG9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YKG9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKG9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YKJ4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKJ4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YKJ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKJ4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YME4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YME4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YME4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YME4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YME8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YME8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YME8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YME8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YSB8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSB8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YSB8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSB8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVCSEKEREDGFKLEEGTFSIDTMKKVFTVRVVRHWHWLPREVVDAPFLETLKILNMEWGGEYSLDSSNLDCLLNVLPGELEFQQILNDLDEKIKKNSSSMEQCLKDLQSEVNEICTDEMLQSTDDCLQWLNNCSFVSLRPSSTQHGELMAFLRTLQRLLKNEQNQEEMILHFLLDLSSQCGVSFPSSPSGMSFEFTSSLHAIEDDSTMDVKSLWDDVRLHLRRFLVNRLQSQEETNPSASQQQIQLKTQCIQQLLFLYPGSEVLSKYQNMQNKMVRDLLQNCVLSSCGETNFDKVVHGYQSSIPTLCTIIKEDFYILSGTIDPSSSLKFINETYLDTITEEITVLLERLCELQFKENALHVVKANKISKKHRRTVHAVASQEYHKKGRNFCLTLYQLKCLSQLIKLFLFMEEKIEELSAEILLMPLFSEKNKNVQGVLKKASGELLIGETRANEASVLPEPLLQVKEPISLNFGWRNAFKDLSSSVAHCITIAIQDFSTKILQHEQQEQSSAAGYAMSLVNNQQIRETCRAVQQEEQPKRIAKFCSDIMGELDTLLPLALACRDDSLQEIRANFVEACSKVATAVLARLEEKSEDVPSKAPLQNLYAALSTAIYVYQHFTMYSNLMRESSKKPLFLVPVQQYQEFINVLQFQVTNYCVRVCATSILQDAESHHWDDYKAFYEGERCSFSVQMWHYFCCALHHDLWTILPPKLAQEILTDVLEQSLAVLSSRYSQACPSYKRTPQIRIDIAAILMSTENMLWSVCSSVQEFLNPHEDRDLKIYKIHSHCNNMLSVLAILTSPLKDLYEMLLNNSGEHPPHGFFDSFYNPLHWLFCIPSSSASLLKSPSAREMAAQGQLKLLLSQPYCNLNLLLETLLYHDCLLVKILLKSSRSEVLAGDEQSSLSDEINNKEPTLIETIFAILSDCILSPKSLGIAFEAYMEKEQLWDCLYNMTVSSCGESEPEVIRCLKLTLINSVKGIVKQIVSLMHSWEATENYGTYQHKQIVPESLLKTVPKEWNYTPREMKRKESGKCFTRLAAQAVSIVISKLPTVIACLPPPIKYFFFLAERKMSRNFAELKKAGLLVWNLIVIICRIFEDGNTAELLTGATLDRWSKEKLSLVRVCLESIMGKQKSGPKQVTQKVIQSIEQQRPNWIESQLLKARKLSTDCGSDAIEGAVLEQEGIAFGFTEQKINMMVLDICHKPGGSEYLRQIYHIIRLNEEYLNEQLSCENSPEENITSNQSLLLTLKGREEQAVFNPFQVHSQSCAKVFNQSTITEWNWDWSDLLPSCLGLNQMTFRVLLTHRWEMKEGADLEDEEKVMVEHLKNVYLTQSTPTSEDKEE", "length": 1342, "header": "tr|A0A8V0YE46-1|A0A8V0YE46_CHICK Isoform 1 of KIAA0825 OS=Gallus gallus OX=9031 GN=KIAA0825 PE=4 SV=1 CANONICAL=A0A8V0YE46-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YE46-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE46/entry#A0A8V0YE46-1", "sequence": { "sequence": "MVCSEKEREDGFKLEEGTFSIDTMKKVFTVRVVRHWHWLPREVVDAPFLETLKILNMEWGGEYSLDSSNLDCLLNVLPGELEFQQILNDLDEKIKKNSSSMEQCLKDLQSEVNEICTDEMLQSTDDCLQWLNNCSFVSLRPSSTQHGELMAFLRTLQRLLKNEQNQEEMILHFLLDLSSQCGVSFPSSPSGMSFEFTSSLHAIEDDSTMDVKSLWDDVRLHLRRFLVNRLQSQEETNPSASQQQIQLKTQCIQQLLFLYPGSEVLSKYQNMQNKMVRDLLQNCVLSSCGETNFDKVVHGYQSSIPTLCTIIKEDFYILSGTIDPSSSLKFINETYLDTITEEITVLLERLCELQFKENALHVVKANKISKKHRRTVHAVASQEYHKKGRNFCLTLYQLKCLSQLIKLFLFMEEKIEELSAEILLMPLFSEKNKNVQGVLKKASGELLIGETRANEASVLPEPLLQVKEPISLNFGWRNAFKDLSSSVAHCITIAIQDFSTKILQHEQQEQSSAAGYAMSLVNNQQIRETCRAVQQEEQPKRIAKFCSDIMGELDTLLPLALACRDDSLQEIRANFVEACSKVATAVLARLEEKSEDVPSKAPLQNLYAALSTAIYVYQHFTMYSNLMRESSKKPLFLVPVQQYQEFINVLQFQVTNYCVRVCATSILQDAESHHWDDYKAFYEGERCSFSVQMWHYFCCALHHDLWTILPPKLAQEILTDVLEQSLAVLSSRYSQACPSYKRTPQIRIDIAAILMSTENMLWSVCSSVQEFLNPHEDRDLKIYKIHSHCNNMLSVLAILTSPLKDLYEMLLNNSGEHPPHGFFDSFYNPLHWLFCIPSSSASLLKSPSAREMAAQGQLKLLLSQPYCNLNLLLETLLYHDCLLVKILLKSSRSEVLAGDEQSSLSDEINNKEPTLIETIFAILSDCILSPKSLGIAFEAYMEKEQLWDCLYNMTVSSCGESEPEVIRCLKLTLINSVKGIVKQIVSLMHSWEATENYGTYQHKQIVPESLLKTVPKEWNYTPREMKRKESGKCFTRLAAQAVSIVISKLPTVIACLPPPIKYFFFLAERKMSRNFAELKKAGLLVWNLIVIICRIFEDGNTAELLTGATLDRWSKEKLSLVRVCLESIMGKQKSGPKQVTQKVIQSIEQQRPNWIESQLLKARKLSTDCGSDAIEGAVLEQEGIAFGFTEQKINMMVLDICHKPGGSEYLRQIYHIIRLNEEYLNEQLSCENSPEENITSNQSLLLTLKGREEQAVFNPFQVHSQSCAKVFNQSTITEWNWDWSDLLPSCLGLNQMTFRVLLTHRWEMKEGADLEDEEKVMVEHLKNVYLTQSTPTSEDKEE", "length": 1342, "header": "tr|A0A8V0YE46-1|A0A8V0YE46_CHICK Isoform 1 of KIAA0825 OS=Gallus gallus OX=9031 GN=KIAA0825 PE=4 SV=1 CANONICAL=A0A8V0YE46-1" }, "locus": { "chromosome": "Z", "start_pos": 58894592, "end_pos": 58696890, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032303.1", "url": "https://www.ensembl.org/id/ENSGALT00010032303.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019093.1", "url": "https://www.ensembl.org/id/ENSGALP00010019093.1" } ] } }, { "isoform_ac": "A0A8V0YE52-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE46/entry#A0A8V0YE52-1", "sequence": { "sequence": "MEWGGEYSLDSSNLDCLLNVLPGELEFQQILNDLDEKIKKNSSSMEQCLKDLQSEVNEICTDEMLQSTDDCLQWLNNCSFVSLRPSSTQHGELMAFLRTLQRLLKNEQNQEEMILHFLLDLSSQCGVSFPSSPSGMSFEFTSSLHAIEDDSTMDVKSLWDDVRLHLRRFLVNRLQSQEETNPSASQQQIQLKTQCIQQLLFLYPGSEVLSKYQNMQNKMVRDLLQNCVLSSCGETNFDKVVHGYQSSIPTLCTIIKEDFYILSGTIDPSSSLKFINETYLDTITEEITVLLERLCELQFKENALHVVKANKISKKHRRTVHAVASQEYHKKGRNFCLTLYQLKCLSQLIKLFLFMEEKIEELSAEILLMPLFSEKNKNVQGVLKKASGELLIGETRANEASVLPEPLLQVKEPISLNFGWRNAFKDLSSSVAHCITIAIQDFSTKILQHEQQEQSSAAGYAMSLVNNQQIRETCRAVQQEEQPKRIAKFCSDIMGELDTLLPLALACRDDSLQEIRANFVEACSKVATAVLARLEEKSEDVPSKAPLQNLYAALSTAIYVYQHFTMYSNLMRESSKKPLFLVPVQQYQEFINVLQFQVTNYCVRVCATSILQDAESHHWDDYKAFYEGERCSFSVQMWHYFCCALHHDLWTILPPKLAQEILTDVLEQSLAVLSSRYSQACPSYKRTPQIRIDIAAILMSTENMLWSVCSSVQEFLNPHEDRDLKIYKIHSHCNNMLSVLAILTSPLKDLYEMLLNNSGEHPPHGFFDSFYNPLHWLFCIPSSSASLLNEVLAGDEQSSLSDEINNKEPTLIETIFAILSDCILSPKSLGIAFEAYMEKEQLWDCLYNMTVSSCGESEPEVIRCLKLTLINSVKGIVKQIVSLMHSWEATENYGTYQHKQIVPESLLKTVPKEWNYTPREMKRKESGKCFTRLAAQAVSIVISKLPTVIACLPPPIKYFFFLAERKMSRNFAELKKAGLLVWNLIVIICRIFEDGNTAELLTGATLDRWSKEKLSLVRVCLESIMGKQKSGPKQVTQKVIQSIEQQRPNWIESQLLKARKLSTDCGSDAIEGAVLEQEGIAFGFTEQKINMMVLDICHKPGGSEYLRQIYHIIRLNEEYLNEQLSCENSPEENITSNQSLLLTLKGREEQAVFNPFQVHSQSCAKVFNQSTITEWNWDWSDLLPSCLGLNQMTFRVLLTHRWEMKEGADLEDEEKVMVEHLKNVYLTQSTPTSEDKEE", "length": 1238, "header": "tr|A0A8V0YE52-1|A0A8V0YE52_CHICK Computationally mapped isoform of KIAA0825 OS=Gallus gallus OX=9031 GN=KIAA0825 PE=4 SV=1 CANONICAL=A0A8V0YE46-1" }, "locus": { "chromosome": "Z", "start_pos": 58894592, "end_pos": 58697492, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032308.1", "url": "https://www.ensembl.org/id/ENSGALT00010032308.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019098.1", "url": "https://www.ensembl.org/id/ENSGALP00010019098.1" } ] } }, { "isoform_ac": "A0A8V0YE57-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE46/entry#A0A8V0YE57-1", "sequence": { "sequence": "MEWGGEYSLDSSNLDCLLNVLPGELEFQQILNDLDEKIKKNSSSMEQCLKDLQSEVNEICTDEMLQSTDDCLQWLNNCSFVSLRPSSTQHGELMAFLRTLQRLLKNEQNQEEMILHFLLDLSSQCGVSFPSSPSGMSFEFTSSLHAIEDDSTMDVKSLWDDVRLHLRRFLVNRLQSQEETNPSASQQQIQLKTQCIQQLLFLYPGSEVLSKYQNMQNKMVRDLLQNCVLSSCGETNFDKVVHGYQSSIPTLCTIIKEDFYILSGTIDPSSSLKFINETYLDTITEEITVLLERLCELQFKENALHVVKANKISKKHRRTVHAVASQEYHKKGRNFCLTLYQLKCLSQLIKLFLFMEEKIEELSAEILLMPLFSEKNKNVQGVLKKASGELLIGETRANEASVLPEPLLQVKEFCSDIMGELDTLLPLALACRDDSLQEIRANFVEACSKVATAVLARLEEKSEDVPSKAPLQNLYAALSTAIYVYQHFTMYSNLMRESSKKPLFLVPVQQYQEFINVLQFQVTNYCVRVCATSILQDAESHHWDDYKAFYEGERCSFSVQMWHYFCCALHHDLWTILPPKLAQEILTDVLEQSLAVLSSRYSQACPSYKRTPQIRIDIAAILMSTENMLWSVCSSVQEFLNPHEDRDLKIYKIHSHCNNMLSVLAILTSPLKDLYEMLLNNSGEHPPHGFFDSFYNPLHWLFCIPSSSASLLKSPSAREMAAQGQLKLLLSQPYCNLNLLLETLLYHDCLLVKILLKSSRSEVLAGDEQSSLSDEINNKEPTLIETIFAILSDCILSPKSLGIAFEAYMEKEQLWDCLYNMTVSSCGESEPEVIRCLKLTLINSVKGIVKQIVSLMHSWEATENYGTYQHKQIVPESLLKTVPKEWNYTPREMKRKESGKCFTRLAAQAVSIVISKLPTVIACLPPPIKYFFFLAERKMSRNFAELKKAGLLVWNLIVIICRIFEDGNTAELLTGATLDRWSKEKLSLVRVCLESIMGKQKSGPKQVTQKVIQSIEQQRPNWIESQLLKARKLSTDCGSDAIEGAVLEQEGIAFGFTEQKINMMVLDICHKPGGSEYLRQIYHIIRLNEEYLNEQLSCENSPEENITSNQSLLLTLKGREEQAVFNPFQVHSQSCAKVFNQSTITEWNWDWSDLLPSCLGLNQMTFRVLLTHRWEMKEGADLEDEEKVMVEHLKNVYLTQSTPTSEDKEE", "length": 1210, "header": "tr|A0A8V0YE57-1|A0A8V0YE57_CHICK Computationally mapped isoform of KIAA0825 OS=Gallus gallus OX=9031 GN=KIAA0825 PE=4 SV=1 CANONICAL=A0A8V0YE46-1" }, "locus": { "chromosome": "Z", "start_pos": 58894592, "end_pos": 58697492, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032313.1", "url": "https://www.ensembl.org/id/ENSGALT00010032313.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019103.1", "url": "https://www.ensembl.org/id/ENSGALP00010019103.1" } ] } }, { "isoform_ac": "A0A8V0YJT8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE46/entry#A0A8V0YJT8-1", "sequence": { "sequence": "MEWGGEYSLDSSNLDCLLNVLPGELEFQQILNDLDEKIKKNSSSMEQCLKDLQSEVNEICTDEMLQSTDDCLQWLNNCSFVSLRPSSTQHGELMAFLRTLQRLLKNEQNQEEMILHFLLDLSSQCGVSFPSSPSGMSFEFTSSLHAIEDDSTMDVKSLWDDVRLHLRRFLVNRLQSQEETNPSASQQQIQLKTQCIQQLLFLYPGSEVLSKYQNMQNKMVRDLLQNCVLSSCGETNFDKVVHGYQSSIPTLCTIIKEDFYILSGTIDPSSSLKFINETYLDTITEEITVLLERLCELQFKENALHVVKANKISKKHRRTVHAVASQEYHKKGRNFCLTLYQLKCLSQLIKLFLFMEEKIEELSAEILLMPLFSEKNKNVQGVLKKASGELLIGETRANEASVLPEPLLQVKEPISLNFGWRNAFKDLSSSVAHCITIAIQDFSTKILQHEQQEQSSAAGYAMSLVNNQQIRETCRAVQQEEQPKRIAKFCSDIMGELDTLLPLALACRDDSLQEIRANFVEACSKVATAVLARLEEKSEDVPSKAPLQNLYAALSTAIYVYQHFTMYSNLMRESSKKPLFLVPVQQYQEFINVLQFQVTNYCVRVCATSILQDAESHHWDDYKAFYEGERCSFSVQMWHYFCCALHHDLWTILPPKLAQEILTDVLEQSLAVLSSRYSQACPSYKRTPQIRIDIAAILMSTENMLWSVCSSVQEFLNPHEDRDLKIYKIHSHCNNMLSVLAILTSPLKDLYEMLLNNSGEHPPHGFFDSFYNPLHWLFCIPSSSASLLKSPSAREMAAQGQLKLLLSQPYCNLNLLLETLLYHDCLLVKILLKSSRSEVLAGDEQSSLSDEINNKEPTLIETIFAILSDCILSPKSLGIAFEAYMEKEQLWDCLYNMTVSSCGESEPEVIRCLKLTLINSVKGIVKQIVSLMHSWEATENYGTYQHKQIVPESLLKTVPKEWNYTPREMKRKESGKCFTRLAAQAVSIVISKLPTVIACLPPPIKYFFFLAERKMSRNFAELKKAGLLVWNLIVIICRIFEDGNTAELLTGATLDRWSKEKLSLVRVCLESIMGKQKSGPKQVTQKVIQSIEQQRPNWIESQLLKARKLSTDCGSDAIEGAVLEQEGIAFGFTEQKINMMVLDICHKPGGSEYLRQIYHIIRLNEIVKCS", "length": 1170, "header": "tr|A0A8V0YJT8-1|A0A8V0YJT8_CHICK Computationally mapped isoform of KIAA0825 OS=Gallus gallus OX=9031 GN=KIAA0825 PE=4 SV=1 CANONICAL=A0A8V0YE46-1" }, "locus": { "chromosome": "Z", "start_pos": 58781406, "end_pos": 58697492, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032287.1", "url": "https://www.ensembl.org/id/ENSGALT00010032287.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019077.1", "url": "https://www.ensembl.org/id/ENSGALP00010019077.1" } ] } }, { "isoform_ac": "A0A8V0YJW9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE46/entry#A0A8V0YJW9-1", "sequence": { "sequence": "MEWGGEYSLDSSNLDCLLNVLPGELEFQQILNDLDEKIKKNSSSMEQCLKDLQSEVNEICTDEMLQSTDDCLQWLNNCSFVSLRPSSTQHGELMAFLRTLQRLLKNEQNQEEMILHFLLDLSSQCGVSFPSSPSGMSFEFTSSLHAIEDDSTMDVKSLWDDVRLHLRRFLVNRLQSQEETNPSASQQQIQLKTQCIQQLLFLYPGSEVLSKYQNMQNKMVRDLLQNCVLSSCGETNFDKVVHGYQSSIPTLCTIIKEDFYILSGTIDPSSSLKFINETYLDTITEEITVLLERLCELQFKENALHVVKANKISKKHRRTVHAVASQEYHKKGRNFCLTLYQLKCLSQLIKLFLFMEEKIEELSAEILLMPLFSEKNKNVQGVLKKASGELLIGETRANEASVLPEPLLQVKEPISLNFGWRNAFKDLSSSVAHCITIAIQDFSTKILQHEQQEQSSAAGYAMSLVNNQQIRETCRAVQQEEQPKRIAKFCSDIMGELDTLLPLALACRDDSLQEIRANFVEACSKVATAVLARLEEKSEDVPSKAPLQNLYAALSTAIYVYQHFTMYSNLMRESSKKPLFLVPVQQYQEFINVLQFQVTNYCVRVCATSILQDAESHHWDDYKAFYEGERCSFSVQMWHYFCCALHHDLWTILPPKLAQEILTDVLEQSLAVLSSRYSQACPSYKRTPQIRIDIAAILMSTENMLWSVCSSVQEFLNPHEDRDLKIYKIHSHCNNMLSVLAILTSPLKDLYEMLLNNSGEHPPHGFFDSFYNPLHWLFCIPSSSASLLKSPSAREMAAQGQLKLLLSQGWGRVQGPFLSSGGCVLLIAGSKPCEV", "length": 835, "header": "tr|A0A8V0YJW9-1|A0A8V0YJW9_CHICK Computationally mapped isoform of KIAA0825 OS=Gallus gallus OX=9031 GN=KIAA0825 PE=4 SV=1 CANONICAL=A0A8V0YE46-1" }, "locus": { "chromosome": "Z", "start_pos": 58895084, "end_pos": 58697492, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032321.1", "url": "https://www.ensembl.org/id/ENSGALT00010032321.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019107.1", "url": "https://www.ensembl.org/id/ENSGALP00010019107.1" } ] } }, { "isoform_ac": "A0A8V0YKG9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE46/entry#A0A8V0YKG9-1", "sequence": { "sequence": "MEWGGEYSLDSSNLDCLLNVLPGELEFQQILNDLDEKIKKNSSSMEQCLKDLQSEVNEICTDEMLQSTDDCLQWLNNCSFVSLRPSSTQHGELMAFLRTLQRLLKNEQNQEEMILHFLLDLSSQCGVSFPSSPSGMSFEFTSSLHAIEDDSTMDVKSLWDDVRLHLRRFLVNRLQSQEETNPSASQQQIQLKTQCIQQLLFLYPGSEVLSKYQNMQNKMVRDLLQNCVLSSCGETNFDKVVHGYQSSIPTLCTIIKEDFYILSGTIDPSSSLKFINETYLDTITEEITVLLERLCELQFKENALHVVKANKISKKHRRTVHAVASQEYHKKGRNFCLTLYQLKCLSQLIKLFLFMEEKIEELSAEILLMPLFSEKNKNVQGVLKKASGELLIGETRANEASVLPEPLLQVKEPISLNFGWRNAFKDLSSSVAHCITIAIQDFSTKILQHEQQEQSSAAGYAMSLVNNQQIRETCRAVQQEEQPKRIAKFCSDIMGELDTLLPLALACRDDSLQEIRANFVEACSKVATAVLARLEEKSEDVPSKAPLQNLYAALSTAIYVYQHFTMYSNLMRESSKKPLFLVPVQQYQEFINVLQFQVTNYCVRVCATSILQDAESHHWDDYKAFYEGERCSFSVQMWHYFCCALHHDLWTILPPKLAQEILTDVLEQSLAVLSSRYSQACPSYKRTPQIRIDIAAILMSTENMLWSVCSSVQEFLNPHEDRDLKIYKIHSHCNNMLSVLAILTSPLKDLYEMLLNNSGEHPPHGFFDSFYNPLHWLFCIPSSSASLLKSPSAREMAAQGQLKLLLSQPYCNLNLLLETLLYHDCLLVKILLKSSRSEVLAGDEQSSLSDEINNKEPTLIETIFAILSDCILSPKSLGIAFEAYMEKEQLWDCLYNMTVSSCGESEPEVIRCLKLTLINSVKGIVKQIVSLMHSWEATENYGTYQHKQIVPESLLKTVPKEWNYTPREMKRKESGKCFTRLAAQAVSIVISKLPTVIACLPPPIKYFFFLAERKMSRNFAELKKAGLLVWNLIVIICRIFEDGNTAELLTGATLDRWSKEKLSLVRVCLESIMGKQKSGPKQVTQKVIQSIEQQRPNWIESQLLKARKLSTDCGSDAIEGAVLEQEGIAFGFTEQKINMMVLDICHKPGGSEYLRQIYHIIRLNEEYLNEQLSCENSPEENITSNQSLLLTLKGREEQAVFNPFQVHSQSCAKVFNQSTITEWNWDWSDLLPSCLGLNQMTFRVLLTHR", "length": 1249, "header": "tr|A0A8V0YKG9-1|A0A8V0YKG9_CHICK Computationally mapped isoform of KIAA0825 OS=Gallus gallus OX=9031 GN=KIAA0825 PE=4 SV=1 CANONICAL=A0A8V0YE46-1" }, "locus": { "chromosome": "Z", "start_pos": 58788249, "end_pos": 58697492, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032290.1", "url": "https://www.ensembl.org/id/ENSGALT00010032290.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019080.1", "url": "https://www.ensembl.org/id/ENSGALP00010019080.1" } ] } }, { "isoform_ac": "A0A8V0YKJ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE46/entry#A0A8V0YKJ4-1", "sequence": { "sequence": "MEWGGEYSLDSSNLDCLLNVLPGELEFQQILNDLDEKIKKNSSSMEQCLKDLQSEVNEICTDEMLQSTDDCLQWLNNCSFVSLRPSSTQHGELMAFLRTLQRLLKNEQNQEEMILHFLLDLSSQCGVSFPSSPSGMSFEFTSSLHAIEDDSTMDVKSLWDDVRLHLRRFLVNRLQSQEETNPSASQQQIQLKTQCIQQLLFLYPGSEVLSKYQNMQNKMVRDLLQNCVLSSCGETNFDKVVHGYQSSIPTLCTIIKEDFYILSGTIDPSSSLKFINETYLDTITEEITVLLERLCELQFKENALHVVKANKISKKHRRTVHAVASQEYHKKGRNFCLTLYQLKCLSQLIKLFLFMEEKIEELSAEILLMPLFSEKNKNVQGVLKKASGELLIGETRANEASVLPEPLLQVKEPISLNFGWRNAFKDLSSSVAHCITIAIQDFSTKILQHEQQEQSSAAGYAMSLVNNQQIRETCRAVQQEEQPKRIAKFCSDIMGELDTLLPLALACRDDSLQEIRANFVEACSKVATAVLARLEEKSEDVPSKAPLQNLYAALSTAIYVYQHFTMYSNLMRESSKKPLFLVPVQQYQEFINVLQFQVTNYCVRVCATSILQDAESHHWDDYKAFYEGERCSFSVQMWHYFCCALHHDLWTILPPKLAQEILTDVLEQSLAVLSSRYSQACPSYKRTPQIRIDIAAILMSTENMLWSVCSSVQEFLNPHEDRDLKIYKIHSHCNNMLSVLAILTSPLKDLYEMLLNNSGEHPPHGFFDSFYNPLHWLFCIPSSSASLLKSPSAREMAAQGQLKLLLSQPYCNLNLLLETLLYHDCLLVKILLKSSRSEVLAGDEQSSLSDEINNKEPTLIETIFAILSDCILSPKSLGIAFEAYMEKEQLWDCLYNMTVSSCGESEPEVIRCLKLTLINSVKGIVKQIVSLMHSWEATENYGTYQHKQIVPESLLKTVPKEWNYTPREMKRKESGKCFTRLAAQAVSIVISKLPTVIACLPPPIKYFFFLAERKMSRNFAELKKAGLLVWNLIVIICRIFEDGNTAELLTGATLDRWSKEKLSLVRVCLESIMGKQKSGPKQVTQKVIQSIEQQRPNWIESQLLKARKLSTDCGSDAIEGAVLEQEGIAFGFTEQKINMMVLDICHKPGGSEYLRQIYHIIRLNEEYLNEQLSCENSPEENITSNQSLLLTLKGREEQAVFNPFQVHSQSCAKVFNQSTITEWNWDWSDLLPSCLGLNQMTFRVLLTHRNYGDNFKHAICRWEMKEGADLEDEEKVMVEHLKNVYLTQSTPTSEDKEE", "length": 1298, "header": "tr|A0A8V0YKJ4-1|A0A8V0YKJ4_CHICK Computationally mapped isoform of KIAA0825 OS=Gallus gallus OX=9031 GN=KIAA0825 PE=4 SV=1 CANONICAL=A0A8V0YE46-1" }, "locus": { "chromosome": "Z", "start_pos": 58894592, "end_pos": 58697492, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032317.1", "url": "https://www.ensembl.org/id/ENSGALT00010032317.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019105.1", "url": "https://www.ensembl.org/id/ENSGALP00010019105.1" } ] } }, { "isoform_ac": "A0A8V0YME4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE46/entry#A0A8V0YME4-1", "sequence": { "sequence": "MKILNMEWGGEYSLDSSNLDCLLNVLPGELEFQQILNDLDEKIKKNSSSMEQCLKDLQSEVNEICTDEMLQSTDDCLQWLNNCSFVSLRPSSTQHGELMAFLRTLQRLLKNEQNQEEMILHFLLDLSSQCGVSFPSSPSGMSFEFTSSLHAIEDDSTMDVKSLWDDVRLHLRRFLVNRLQSQEETNPSASQQQIQLKTQCIQQLLFLYPGSEVLSKYQNMQNKMVRDLLQNCVLSSCGETNFDKVVHGYQSSIPTLCTIIKEDFYILSGTIDPSSSLKFINETYLDTITEEITVLLERLCELQFKENALHVVKANKISKKHRRTVHAVASQEYHKKGRNFCLTLYQLKCLSQLIKLFLFMEEKIEELSAEILLMPLFSEKNKNVQGVLKKASGELLIGETRANEASVLPEPLLQVKEPISLNFGWRNAFKDLSSSVAHCITIAIQDFSTKILQHEQQEQSSAAGYAMSLVNNQQIRETCRAVQQEEQPKRIAKFCSDIMGELDTLLPLALACRDDSLQEIRANFVEACSKVATAVLARLEEKSEDVPSKAPLQNLYAALSTAIYVYQHFTMYSNLMRESSKKPLFLVPVQQYQEFINVLQFQVTNYCVRVCATSILQDAESHHWDDYKAFYEGERCSFSVQMWHYFCCALHHDLWTILPPKLAQEILTDVLEQSLAVLSSRYSQACPSYKRTPQIRIDIAAILMSTENMLWSVCSSVQEFLNPHEDRDLKIYKIHSHCNNMLSVLAILTSPLKDLYEMLLNNSGEHPPHGFFDSFYNPLHWLFCIPSSSASLLKSPSAREMAAQGQLKLLLSQPYCNLNLLLETLLYHDCLLVKILLKSSRSEVLAGDEQSSLSDEINNKEPTLIETIFAILSDCILSPKSLGIAFEAYMEKEQLWDCLYNMTVSSCGESEPEVIRCLKLTLINSVKGIVKQIVSLMHSWEATENYGTYQHKQIVPESLLKTVPKEWNYTPREMKRKESGKCFTRLAAQAVSIVISKLPTVIACLPPPIKYFFFLAERKMSRNFAELKKAGLLVWNLIVIICRIFEDGNTAELLTGATLDRWSKEKLSLVRVCLESIMGKQKSGPKQVTQKVIQSIEQQRPNWIESQLLKARKLSTDCGSDAIEGAVLEQEGIAFGFTEQKINMMVLDICHKPGGSEYLRQIYHIIRLNEEYLNEQLSCENSPEENITSNQSLLLTLKGREEQAVFNPFQVHSQSCAKVFNQSTITEWNWDWSDLLPSCLGLNQMTFRVLLTHRWEMKEGADLEDEEKVMVEHLKNVYLTQSTPTSEDKEE", "length": 1291, "header": "tr|A0A8V0YME4-1|A0A8V0YME4_CHICK Computationally mapped isoform of KIAA0825 OS=Gallus gallus OX=9031 GN=KIAA0825 PE=4 SV=1 CANONICAL=A0A8V0YE46-1" }, "locus": { "chromosome": "Z", "start_pos": 58894592, "end_pos": 58675050, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032306.1", "url": "https://www.ensembl.org/id/ENSGALT00010032306.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019096.1", "url": "https://www.ensembl.org/id/ENSGALP00010019096.1" } ] } }, { "isoform_ac": "A0A8V0YME8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE46/entry#A0A8V0YME8-1", "sequence": { "sequence": "MEWGGEYSLDSSNLDCLLNVLPGELEFQQILNDLDEKIKKNSSSMEQCLKDLQSEVNEICTDEMLQSTDDCLQWLNNCSFVSLRPSSTQHGELMAFLRTLQRLLKNEQNQEEMILHFLLDLSSQCGVSFPSSPSGMSFEFTSSLHAIEDDSTMDVKSLWDDVRLHLRRFLVNRLQSQEETNPSASQQQIQLKTQCIQQLLFLYPGSEVLSKYQNMQNKMVRDLLQNCVLSSCGETNFDKVVHGYQSSIPTLCTIIKEDFYILSGTIDPSSSLKFINETYLDTITEEITVLLERLCELQFKENALHVVKANKISKKHRRTVHAVGVLKKASGELLIGETRANEASVLPEPLLQVKEPISLNFGWRNAFKDLSSSVAHCITIAIQDFSTKILQHEQQEQSSAAGYAMSLVNNQQIRETCRAVQQEEQPKRIAKFCSDIMGELDTLLPLALACRDDSLQEIRANFVEACSKVATAVLARLEEKSEDVPSKAPLQNLYAALSTAIYVYQHFTMYSNLMRESSKKPLFLVPVQQYQEFINVLQFQVTNYCVRVCATSILQDAESHHWDDYKAFYEGERCSFSVQMWHYFCCALHHDLWTILPPKLAQEILTDVLEQSLAVLSSRYSQACPSYKRTPQIRIDIAAILMSTENMLWSVCSSVQEFLNPHEDRDLKIYKIHSHCNNMLSVLAILTSPLKDLYEMLLNNSGEHPPHGFFDSFYNPLHWLFCIPSSSASLLKSPSAREMAAQGQLKLLLSQPYCNLNLLLETLLYHDCLLVKILLKSSRSEVLAGDEQSSLSDEINNKEPTLIETIFAILSDCILSPKSLGIAFEAYMEKEQLWDCLYNMTVSSCGESEPEVIRCLKLTLINSVKGIVKQIVSLMHSWEATENYGTYQHKQIVPESLLKTVPKEWNYTPREMKRKESGKCFTRLAAQAVSIVISKLPTVIACLPPPIKYFFFLAERKMSRNFAELKKAGLLVWNLIVIICRIFEDGNTAELLTGATLDRWSKEKLSLVRVCLESIMGKQKSGPKQVTQKVIQSIEQQRPNWIESQLLKARKLSTDCGSDAIEGAVLEQEGIAFGFTEQKINMMVLDICHKPGGSEYLRQIYHIIRLNEEYLNEQLSCENSPEENITSNQSLLLTLKGREEQAVFNPFQVHSQSCAKVFNQSTITEWNWDWSDLLPSCLGLNQMTFRVLLTHRWEMKEGADLEDEEKVMVEHLKNVYLTQSTPTSEDKEE", "length": 1229, "header": "tr|A0A8V0YME8-1|A0A8V0YME8_CHICK Computationally mapped isoform of KIAA0825 OS=Gallus gallus OX=9031 GN=KIAA0825 PE=4 SV=1 CANONICAL=A0A8V0YE46-1" }, "locus": { "chromosome": "Z", "start_pos": 58894592, "end_pos": 58697492, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032311.1", "url": "https://www.ensembl.org/id/ENSGALT00010032311.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019101.1", "url": "https://www.ensembl.org/id/ENSGALP00010019101.1" } ] } }, { "isoform_ac": "A0A8V0YSB8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE46/entry#A0A8V0YSB8-1", "sequence": { "sequence": "MEWGGEYSLDSSNLDCLLNVLPGELEFQQILNDLDEKIKKNSSSMEQCLKDLQSEVNEICTDEMLQSTDDCLQWLNNCSFVSLRPSSTQHGELMAFLRTLQRLLKNEQNQEEMILHFLLDLSSQCGVSFPSSPSGMSFEFTSSLHAIEDDSTMDVKSLWDDVRLHLRRFLVNRLQSQEETNPSASQQQIQLKTQCIQQLLFLYPGSEVLSKYQNMQNKMVRDLLQNCVLSSCGETNFDKVVHGYQSSIPTLCTIIKEDFYILSGTIDPSSSLKFINETYLDTITEEITVLLERLCELQFKENALHVVKANKISKKHRRTVHAVASQEYHKKGRNFCLTLYQLKCLSQLIKLFLFMEEKIEELSAEILLMPLFSEKNKNVQGVLKKASGELLIGETRANEASVLPEPLLQVKEPISLNFGWRNAFKDLSSSVAHCITIAIQDFSTKILQHEQQEQSSAAGYAMSLVNNQQIRETCRAVQQEEQPKRIAKFCSDIMGELDTLLPLALACRDDSLQEIRANFVEACSKVATAVLARLEEKSEDVPSKAPLQNLYAALSTAIYVYQHFTMYSNLMRESSKKPLFLVPVQQYQEFINVLQFQVTNYCVRVCATSILQDAESHHWDDYKAFYEGERCSFSVQMWHYFCCALHHDLWTILPPKLAQEILTDVLEQSLAVLSSRYSQACPSYKRTPQIRIDIAAILMSTENMLWSVCSSVQEFLNPHEDRDLKIYKIHSHCNNMLSVLAILTSPLKDLYEMLLNNSGEHPPHGFFDSFYNPLHWLFCIPSSSASLLKSPSAREMAAQGQLKLLLSQPYCNLNLLLETLLYHDCLLVKILLKSSRSEVLAGDEQSSLSDEINNKEPTLIETIFAILSDCILSPKSLGIAFEAYMEKEQLWDCLYNMTVSSCGESEPEVIRCLKLTLINSVKGIVKQIVSLMHSWEATENYGTYQHKQIVPESLLKTVPKEWNYTPREMKRKESGKCFTRLAAQAVSIVISKLPTVIACLPPPIKYFFFLAERKMSRNFAELKKAGLLVWNLIVIICRIFEDGNTAELLTGATLDRWSKEKLSLVRVCLESIMGKQKSGPKQVTQKVIQSIEQQRPNWIESQLLKARKLSTDCGSDAIEGAVLEQEGIAFGFTEQKINMMVLDICHKPGGSEYLRQIYHIIRLNEEYLNEQLSCENSPEENITSNQSLLLTLKGREEQAVFNPFQVHSQSCAKVFNQSTITEWNWDWSDLLPSCLGLNQMTFRVLLTHRNYGDNFKHAICRYLGRTTVEG", "length": 1270, "header": "tr|A0A8V0YSB8-1|A0A8V0YSB8_CHICK Computationally mapped isoform of KIAA0825 OS=Gallus gallus OX=9031 GN=KIAA0825 PE=4 SV=1 CANONICAL=A0A8V0YE46-1" }, "locus": { "chromosome": "Z", "start_pos": 58797707, "end_pos": 58697492, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032299.1", "url": "https://www.ensembl.org/id/ENSGALT00010032299.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019089.1", "url": "https://www.ensembl.org/id/ENSGALP00010019089.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 1019, "end_pos": 1021, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1237, "end_pos": 1239, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1241, "end_pos": 1243, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1272, "end_pos": 1274, "annotation": "n_glycosylation_sequon" }, { "start_pos": 133, "end_pos": 135, "annotation": "n_glycosylation_sequon" }, { "start_pos": 332, "end_pos": 334, "annotation": "n_glycosylation_sequon" }, { "start_pos": 812, "end_pos": 814, "annotation": "n_glycosylation_sequon" }, { "start_pos": 952, "end_pos": 954, "annotation": "n_glycosylation_sequon" }, { "start_pos": 97, "end_pos": 99, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1019, "end_pos": 1021 }, { "start_pos": 1237, 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0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YE66-1", "uniprot_ac": "A0A8V0YE66", "uniprot_id": "A0A8V0YE66_CHICK", "mass": { "chemical_mass": 30531.0, "monoisotopic_mass": 30531.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Ricin B lectin domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A8V0YE66", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE66/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YE66", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE66" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE66", "locus": {} } ], "crossref": [ { "id": "A0A8V0YE66", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YE66", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd23436", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd23436", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR029044", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029044", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035992", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035992", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR11675", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11675", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11675:SF130", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11675:SF130", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YE66", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE66", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YE66-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE66-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPALGTPAGTATSPAGPLPTSVLHCTKPERGVPARASSAPQVWMCGGEIEIVPCSRVGHIFRNDNPYSFPKDRVRTVERNLARVAEVWLDDYKELFYGHAYHLLQRRAELGDLSQQKALRERLQCRSFRWYLENVYPDLAAPLVKASGLLVNVATARCIAAQNTTLALQACDVNNKAQHFNYTWLRLLQHGELCVVPVGAAGAPGLRPCEGWESGLAWRHSSMAARPELAEHLMVQHQHPPACLLVHPVLLALRLGACTTTDRYQQWRFGSYHVA", "length": 275, "header": "tr|A0A8V0YE66-1|A0A8V0YE66_CHICK Isoform 1 of Ricin B lectin domain-containing protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0YE66-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YE66-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE66/entry#A0A8V0YE66-1", "sequence": { "sequence": "MPALGTPAGTATSPAGPLPTSVLHCTKPERGVPARASSAPQVWMCGGEIEIVPCSRVGHIFRNDNPYSFPKDRVRTVERNLARVAEVWLDDYKELFYGHAYHLLQRRAELGDLSQQKALRERLQCRSFRWYLENVYPDLAAPLVKASGLLVNVATARCIAAQNTTLALQACDVNNKAQHFNYTWLRLLQHGELCVVPVGAAGAPGLRPCEGWESGLAWRHSSMAARPELAEHLMVQHQHPPACLLVHPVLLALRLGACTTTDRYQQWRFGSYHVA", "length": 275, "header": "tr|A0A8V0YE66-1|A0A8V0YE66_CHICK Isoform 1 of Ricin B lectin domain-containing protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0YE66-1" }, "locus": { "chromosome": "7", "start_pos": 35819484, "end_pos": 35816575, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010025129.1", "url": "https://www.ensembl.org/id/ENSGALT00010025129.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010014260.1", "url": "https://www.ensembl.org/id/ENSGALP00010014260.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 6, "start_aa": "Thr", "end_pos": 6, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr6", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 163, "end_pos": 165, "annotation": "n_glycosylation_sequon" }, { "start_pos": 181, "end_pos": 183, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 6 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 163, "end_pos": 165 }, { "start_pos": 181, "end_pos": 183 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YE74-1", "uniprot_ac": "A0A8V0YE74", "uniprot_id": "A0A8V0YE74_CHICK", "mass": { "chemical_mass": 51579.0, "monoisotopic_mass": 51579.0 }, "refseq": {}, "gene_names": [ { "name": "RAD52", "type": "recommended", "evidence": [ { "id": "A0A8V0YE74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE74" } ] } ], "protein_names": [ { "name": "DNA repair protein RAD52 homolog", "type": "recommended", "evidence": [ { "id": "A0A8V0YE74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE74/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Involved in double-stranded break repair. Plays a central role in genetic recombination and DNA repair by promoting the annealing of complementary single-stranded DNA and by stimulation of the RAD51 recombinase.", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NXF5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NXF5#function" }, { "database": "UniProtKB", "id": "ARBA00053354", "url": "https://www.uniprot.org/uniprotkb/ARBA00053354#function" }, { "database": "UniProtKB", "id": "A0A8V0YE74", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE74#function" }, { "database": "UniProtKB", "id": "A0A8V0YFD8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFD8#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YE74", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE74" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RAD52", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE74", "locus": { "chromosome": "1", "start_pos": 60590254, "end_pos": 60605589, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012367", "url": "https://www.ensembl.org/id/ENSGALG00010012367" } ] } } ], "crossref": [ { "id": "A0A8V0YE74", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YE74", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000039171", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000039171", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "418152", "url": "https://www.ncbi.nlm.nih.gov/gene/418152", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004585", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004585", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007232", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007232", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041247", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041247", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042525", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042525", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "RITGNWE", "url": "https://omabrowser.org/oma/group/RITGNWE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5NXF5", "url": "https://www.orthodb.org/?gene=A0A1D5NXF5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YE74", "url": "https://www.orthodb.org/?gene=A0A8V0YE74", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YFD8", "url": "https://www.orthodb.org/?gene=A0A8V0YFD8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12132", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12132", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12132:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12132:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04098", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04098", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-3108214", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3108214", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-5685938", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5685938", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-5685939", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5685939", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A1D5NXF5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NXF5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5NXF5-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NXF5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YE74", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE74", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YE74-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE74-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YFD8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFD8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YFD8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFD8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MFLRRILAAVKQHQKTNFQLILQQFHRSTHRRMPERQGKDSESHVSSSCTSTSNSVACFGQYQYTANEYQAIQHALRQKLGPEYISSRQAGGGQKVCYIEGHKVISLANEMFGFNGWAHSVTQQNVDFVDLNNGRFYVGVCAFVKVQLKDGSYHEDVGYGVSEGLKSKALSLEKARKEAVTDGLKRALKCFGNALGNCILDKDYLQAVNKLPRQMPPELDLVKTKRQDYEPEIEKARYDGCLERQNPGWRQQCETAPTCKPTHTEASGVTEDQKQPSSSGNTDSPAVECDATYQRKLRQKQLQQQFWEQMEKRRQVKEVTPSSKQATANPPVKHSTPAAVQQELAIEEEFFADDLELWDISLETTDLNKLMCHKAAGSPAAQQPPETPHRRHQMTTRNRTPQRMHYHKPPVRFAQLQPSAALTSNSHGANQRTPAEHSPYRRSQSWKKRRLEPT", "length": 454, "header": "tr|A0A8V0YE74-1|A0A8V0YE74_CHICK Isoform 1 of DNA repair protein RAD52 homolog OS=Gallus gallus OX=9031 GN=RAD52 PE=3 SV=1 CANONICAL=A0A8V0YE74-1" }, "isoforms": [ { "isoform_ac": "A0A1D5NXF5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE74/entry#A0A1D5NXF5-1", "sequence": { "sequence": "MPERQGKDSESHVSSSCTSTSNSVACFGQYQYTANEYQAIQHALRQKLGPEYISSRQAGGGQKVCYIEGHKVISLANEMFGFNGWAHSVTQQNVDFVDLNNGRFYVGVCAFVKVQLKDGSYHEDVGYGVSEGLKSKALSLEKARKEAVTDGLKRALKCFGNALGNCILDKDYLQAVNKLPRQMPPELDLVKTKRQDYEPEIEKARYDGCLERQNPGWRQQCETAPTCKPTHTEASGVTEDQKQPSSSGNTDSPAVECDATYQRKLRQKQLQQQFWEQMEKRRQVKEVTPSSKQATANPPVKHSTPAAVQQELAIEEEFFADDLELWDISLETTDLNKLMCHKAAGSPAAQQPPETPHRRHQMTTRNRTPQRMHYHKPPVRFAQLQPSAALTSNSHGANQRTPAEHSPYRRSQSWKKRRLEPT", "length": 422, "header": "tr|A0A1D5NXF5-1|A0A1D5NXF5_CHICK Computationally mapped isoform of DNA repair protein RAD52 homolog OS=Gallus gallus OX=9031 GN=RAD52 PE=3 SV=1 CANONICAL=A0A8V0YE74-1" }, "locus": { "chromosome": "1", "start_pos": 60602284, "end_pos": 60594009, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029620.1", "url": "https://www.ensembl.org/id/ENSGALT00010029620.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017234.1", "url": "https://www.ensembl.org/id/ENSGALP00010017234.1" } ] } }, { "isoform_ac": "A0A8V0YE74-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE74/entry#A0A8V0YE74-1", "sequence": { "sequence": "MFLRRILAAVKQHQKTNFQLILQQFHRSTHRRMPERQGKDSESHVSSSCTSTSNSVACFGQYQYTANEYQAIQHALRQKLGPEYISSRQAGGGQKVCYIEGHKVISLANEMFGFNGWAHSVTQQNVDFVDLNNGRFYVGVCAFVKVQLKDGSYHEDVGYGVSEGLKSKALSLEKARKEAVTDGLKRALKCFGNALGNCILDKDYLQAVNKLPRQMPPELDLVKTKRQDYEPEIEKARYDGCLERQNPGWRQQCETAPTCKPTHTEASGVTEDQKQPSSSGNTDSPAVECDATYQRKLRQKQLQQQFWEQMEKRRQVKEVTPSSKQATANPPVKHSTPAAVQQELAIEEEFFADDLELWDISLETTDLNKLMCHKAAGSPAAQQPPETPHRRHQMTTRNRTPQRMHYHKPPVRFAQLQPSAALTSNSHGANQRTPAEHSPYRRSQSWKKRRLEPT", "length": 454, "header": "tr|A0A8V0YE74-1|A0A8V0YE74_CHICK Isoform 1 of DNA repair protein RAD52 homolog OS=Gallus gallus OX=9031 GN=RAD52 PE=3 SV=1 CANONICAL=A0A8V0YE74-1" }, "locus": { "chromosome": "1", "start_pos": 60602516, "end_pos": 60594009, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029614.1", "url": "https://www.ensembl.org/id/ENSGALT00010029614.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017229.1", "url": "https://www.ensembl.org/id/ENSGALP00010017229.1" } ] } }, { "isoform_ac": "A0A8V0YFD8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE74/entry#A0A8V0YFD8-1", "sequence": { "sequence": "TIQSVFYPYQYTANEYQAIQHALRQKLGPEYISSRQAGGGQKVCYIEGHKVISLANEMFGFNGWAHSVTQQNVDFVDLNNGRFYVGVCAFVKVQLKDGSYHEDVGYGVSEGLKSKALSLEKARKEAVTDGLKRALKCFGNALGNCILDKDYLQAVNKLPRQMPPELDLVKTKRQDYEPEIEKARYDGCLERQNPGWRQQCETAPTCKPTHTEASGVTEDQKQPSSSGNTDSPAVECDATYQRKLRQKQLQQQFWEQMEKRRQVKEVTPSSKQATANPPVKHSTPAAVQQELAIEEEFFADDLELWDISLETTDLNKLMCHKAAGSPAAQQPPETPHRRHQMTTRNRTPQRMHYHKPPVRFAQLQPSAALTSNSHGANQRTPAEHSPYRRSQSWKKRRLEPT", "length": 401, "header": "tr|A0A8V0YFD8-1|A0A8V0YFD8_CHICK Computationally mapped isoform of DNA repair protein RAD52 homolog OS=Gallus gallus OX=9031 GN=RAD52 PE=3 SV=1 CANONICAL=A0A8V0YE74-1" }, "locus": { "chromosome": "1", "start_pos": 60601535, "end_pos": 60594009, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029611.1", "url": "https://www.ensembl.org/id/ENSGALT00010029611.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017227.1", "url": "https://www.ensembl.org/id/ENSGALP00010017227.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-3108214", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3108214", "resource": "Reactome", "description": "SUMOylation of DNA damage response and repair proteins" }, { "id": "R-GGA-5685938", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5685938", "resource": "Reactome", "description": "HDR through Single Strand Annealing (SSA)" }, { "id": "R-GGA-5685939", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5685939", "resource": "Reactome", "description": "HDR through MMEJ (alt-NHEJ)" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZZL1-1", "protein_name": "DNA repair protein RAD52 homolog", "gene_name": "Rad52", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAGAEEAVHGGCDCRPPFVGGKSVLLFGQSQYTADEYQAIQKALRQRLGPEYISSRMAGGGQKVCYIEGHRVINLANEMFGYNGWAHSVTQQNVDFVDLNNGKFYVGVCAFVRVQLKDGSYHEDVGYGVSEGLRSKALSLEKARKEAVTDGLKRALRSFGNALGNCILDKDYLKSLNRLPRQLPLEVDLTTTKREDFEPSVEQARYNSCRQDKASGLPKPQEAASPCRPSHPHDSNIKLQGAKDSSSSSCSLATTSESDATHQRKLRKLRQKQLQQQFREQMEAHRLSHAPAEEVEAKREAALPAPPKHSTPVPAASACLREKAVLPDNLEENLEMWDLTPDLEDIIKPLCRTEPPQTSVTRTLNNQAVIQDSVPHIHCHQKVQEKPGPGHLQTCSTNQHVLGSRGSWKSRDSGFNSIKWKGKKTLNLIGRART", "length": 434 }, "evidence": [ { "id": "A0A8V0YE74", "url": "https://omabrowser.org/oma/group/A0A8V0YE74/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P43351-1", "protein_name": "DNA repair protein RAD52 homolog", "gene_name": "RAD52", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSGTEEAILGGRDSHPAAGGGSVLCFGQCQYTAEEYQAIQKALRQRLGPEYISSRMAGGGQKVCYIEGHRVINLANEMFGYNGWAHSITQQNVDFVDLNNGKFYVGVCAFVRVQLKDGSYHEDVGYGVSEGLKSKALSLEKARKEAVTDGLKRALRSFGNALGNCILDKDYLRSLNKLPRQLPLEVDLTKAKRQDLEPSVEEARYNSCRPNMALGHPQLQQVTSPSRPSHAVIPADQDCSSRSLSSSAVESEATHQRKLRQKQLQQQFRERMEKQQVRVSTPSAEKSEAAPPAPPVTHSTPVTVSEPLLEKDFLAGVTQELIKTLEDNSEKWAVTPDAGDGVVKPSSRADPAQTSDTLALNNQMVTQNRTPHSVCHQKPQAKSGSWDLQTYSADQRTTGNWESHRKSQDMKKRKYDPS", "length": 418 }, "evidence": [ { "id": "A0A8V0YE74", "url": "https://omabrowser.org/oma/group/A0A8V0YE74/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P43352-1", "protein_name": "DNA repair protein RAD52 homolog", "gene_name": "Rad52", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAGPEEAVHRGCDNHPPFVGGKSVLLFGQSQYTADEYQAIQKALRQRLGPEYISSRMAGGGQKVCYIEGHRVINLANEMFGYNGWAHSITQQNVDFVDLNNGKFYVGVCAFVKVQLKDGSYHEDVGYGVSEGLRSKALSLEKARKEAVTDGLKRALRSFGNALGNCILDKDYLRSLNKLPRQLPLDVDLTKTKREDFEPSVEQARYNSCRQNEALGLPKPQEVTSPCRSSPPHDSNIKLQGAKDISSSCSLAATLESDATHQRKLRKLRQKQLQQQFREQMETRRQSHAPAEEVAAKHAAVLPAPPKHSTPVTAASELLQEKVVFPDNLEENLEMWDLTPDLEDIIKPLCRAEPAQTSATRTFNNQDSVPHIHCHQKPQEKPGPGHLQTCNTNQHVLGSREDSEPHRKSQDLKKRKLDPS", "length": 420 }, "evidence": [ { "id": "A0A8V0YE74", "url": "https://omabrowser.org/oma/group/A0A8V0YE74/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "mitotic recombination", "id": "GO:0006312", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006312", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YE74", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE74" } ], "pmid": "" }, { "name": "double-strand break repair via single-strand annealing", "id": "GO:0045002", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045002", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YE74", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE74" } ], "pmid": "" }, { "name": "cellular response to oxidative stress", "id": "GO:0034599", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034599", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YE74", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE74" } ], "pmid": "" }, { "name": "double-strand break repair via homologous recombination", "id": "GO:0000724", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000724", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YE74", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE74" } ], "pmid": "" }, { "name": "DNA double-strand break processing involved in repair via single-strand annealing", "id": "GO:0010792", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010792", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YE74", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE74" } ], "pmid": "" }, { "name": "DNA recombinase assembly", "id": "GO:0000730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000730", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YE74", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE74" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YE74", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE74" } ], "pmid": "" }, { "name": "protein-DNA complex", "id": "GO:0032993", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032993", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YE74", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE74" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YE74", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE74" } ], "pmid": "" }, { "name": "single-stranded DNA binding", "id": "GO:0003697", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003697", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YE74", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE74" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 398, "end_pos": 400, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 398, "end_pos": 400 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YE85-1", "uniprot_ac": "A0A8V0YE85", "uniprot_id": "A0A8V0YE85_CHICK", "mass": { "chemical_mass": 89309.0, "monoisotopic_mass": 89309.0 }, "refseq": {}, "gene_names": [ { "name": "CEP83", "type": "recommended", "evidence": [ { "id": "A0A8V0YE85", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE85" } ] } ], "protein_names": [ { "name": "Centrosomal protein 83", "type": "synonym", "evidence": [ { "id": "A0A8V0YE85", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE85/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YE85", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE85" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CEP83", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE85", "locus": { "chromosome": "1", "start_pos": 45184680, "end_pos": 45208890, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010010573", "url": "https://www.ensembl.org/id/ENSGALG00010010573" } ] } } ], "crossref": [ { "id": "A0A8V0YE85", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YE85", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000019336", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000019336", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "417904", "url": "https://www.ncbi.nlm.nih.gov/gene/417904", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR052116", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052116", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:417904", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417904", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DAYKRKC", "url": "https://omabrowser.org/oma/group/DAYKRKC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y7B1", "url": "https://www.orthodb.org/?gene=A0A8V0Y7B1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YE85", "url": "https://www.orthodb.org/?gene=A0A8V0YE85", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1BZA0", "url": "https://www.orthodb.org/?gene=E1BZA0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23170", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23170", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23170:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23170:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "R-GGA-5620912", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5620912", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0Y7B1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y7B1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y7B1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y7B1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YE85", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE85", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YE85-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE85-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BZA0", "url": "https://www.uniprot.org/uniprotkb/E1BZA0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BZA0-1", "url": "https://www.uniprot.org/uniprotkb/E1BZA0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDSLGSLLPPVVGNGDAANSQELQKLLIDEKMRCEHHKANYQTIKAEHIRLQEEYTKSQDELKRLLVEKQTVHDKFQLLLAEYREELLGKTQELEKLKMQVLTPQKLELLKAQIQQELESPMAERYRKLENEMEKYRTEYNKLRYEHTFLKSEFEHQKEEHEHVLEEEKIKYEAEIARLEKDKEELHNQLVSVDPTRDSKRVEVLSREKAQLCQKLKGLEAEVAELRAERDNCGVQAENVQRVQVRQLAELQSLARSLEAEKKSAEQHIGRIEEELQMCREQNFLLTSKLHKSEQEVNSLAAKVEELKQSHKLEVTNVKLEAARTKNEVERERNKIQSEMDGLLSDKEVLKEAVERHKVLLVEKDQELVRKVQAAKEEVFGKIAALQDEKYVLIYCSASKSLGKSVWSNFLNVIFSNNLLALCCGSSVNTVCFFRLELESRLAHLEKVKLEQDAWRQTEKDQYEEKLRVVQLAEESSKRELQCLRLKIQQQAIQTEELEEKKRERDDLKQQIQDMQLQVASLSQSENDLLEYNQKLKETVERLRQECQNARTQAEKAQLETEKTLEYKRIEWLEEKHMLTQRITEKEEKYNEVKNKLCRAAVAQKKRKTLNDNKQRRMQEKLQLLEAKIEELEKENQVLNRQNVSYEEYARLQKRLKDLQRRHNEFRSLILNPGIPSLNPISATSAPVPPPGPDVPFLFLQEEQHQRELSVLRKRLEDLETTQRKQLQELGPAGERLPARARRELTSSRGAEGAAVQSEDST", "length": 762, "header": "tr|A0A8V0YE85-1|A0A8V0YE85_CHICK Isoform 1 of Centrosomal protein 83 OS=Gallus gallus OX=9031 GN=CEP83 PE=4 SV=1 CANONICAL=A0A8V0YE85-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Y7B1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE85/entry#A0A8V0Y7B1-1", "sequence": { "sequence": "MDSLGSLLPPVVGNGDAANSQELQKLLIDEKMRCEHHKANYQTIKAEHIRLQEEYTKSQDELKRLLVEKQTVHDKFQLLLAEYREELLGKTQELEKLKMQVLTPQKLELLKAQIQQELESPMAERYRKLENEMEKYRTEYNKLRYEHTFLKSEFEHQKEEHEHVLEEEKIKYEAEAEKKSAEQHIGRIEEELQMCREQNFLLTSKLHKSEQEVNSLAAKVEELKQSHKLEVTNVKLEAARTKNEVERERNKIQSEMDGKIHNKFLLAKLISSGFFDNFHLKHFNYFSSKCSPAIFTFCFWSE", "length": 302, "header": "tr|A0A8V0Y7B1-1|A0A8V0Y7B1_CHICK Computationally mapped isoform of Centrosomal protein 83 OS=Gallus gallus OX=9031 GN=CEP83 PE=4 SV=1 CANONICAL=A0A8V0YE85-1" }, "locus": { "chromosome": "1", "start_pos": 45204178, "end_pos": 45194900, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010025182.1", "url": "https://www.ensembl.org/id/ENSGALT00010025182.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010014276.1", "url": "https://www.ensembl.org/id/ENSGALP00010014276.1" } ] } }, { "isoform_ac": "A0A8V0YE85-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE85/entry#A0A8V0YE85-1", "sequence": { "sequence": "MDSLGSLLPPVVGNGDAANSQELQKLLIDEKMRCEHHKANYQTIKAEHIRLQEEYTKSQDELKRLLVEKQTVHDKFQLLLAEYREELLGKTQELEKLKMQVLTPQKLELLKAQIQQELESPMAERYRKLENEMEKYRTEYNKLRYEHTFLKSEFEHQKEEHEHVLEEEKIKYEAEIARLEKDKEELHNQLVSVDPTRDSKRVEVLSREKAQLCQKLKGLEAEVAELRAERDNCGVQAENVQRVQVRQLAELQSLARSLEAEKKSAEQHIGRIEEELQMCREQNFLLTSKLHKSEQEVNSLAAKVEELKQSHKLEVTNVKLEAARTKNEVERERNKIQSEMDGLLSDKEVLKEAVERHKVLLVEKDQELVRKVQAAKEEVFGKIAALQDEKYVLIYCSASKSLGKSVWSNFLNVIFSNNLLALCCGSSVNTVCFFRLELESRLAHLEKVKLEQDAWRQTEKDQYEEKLRVVQLAEESSKRELQCLRLKIQQQAIQTEELEEKKRERDDLKQQIQDMQLQVASLSQSENDLLEYNQKLKETVERLRQECQNARTQAEKAQLETEKTLEYKRIEWLEEKHMLTQRITEKEEKYNEVKNKLCRAAVAQKKRKTLNDNKQRRMQEKLQLLEAKIEELEKENQVLNRQNVSYEEYARLQKRLKDLQRRHNEFRSLILNPGIPSLNPISATSAPVPPPGPDVPFLFLQEEQHQRELSVLRKRLEDLETTQRKQLQELGPAGERLPARARRELTSSRGAEGAAVQSEDST", "length": 762, "header": "tr|A0A8V0YE85-1|A0A8V0YE85_CHICK Isoform 1 of Centrosomal protein 83 OS=Gallus gallus OX=9031 GN=CEP83 PE=4 SV=1 CANONICAL=A0A8V0YE85-1" }, "locus": { "chromosome": "1", "start_pos": 45204178, "end_pos": 45185760, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010025189.1", "url": "https://www.ensembl.org/id/ENSGALT00010025189.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010014280.1", "url": "https://www.ensembl.org/id/ENSGALP00010014280.1" } ] } }, { "isoform_ac": "E1BZA0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE85/entry#E1BZA0-1", "sequence": { "sequence": "MDSLGSLLPPVVGNGDAANSQELQKLLIDEKMRCEHHKANYQTIKAEHIRLQEEYTKSQDELKRLLVEKQTVHDKFQLLLAEYREELLGKTQELEKLKMQVLTPQKLELLKAQIQQELESPMAERYRKLENEMEKYRTEYNKLRYEHTFLKSEFEHQKEEHEHVLEEEKIKYEAEIARLEKDKEELHNQLVSVDPTRDSKRVEVLSREKAQLCQKLKGLEAEVAELRAERDNCGVQAENVQRVQVRQLAELQSLARSLEAEKKSAEQHIGRIEEELQMCREQNFLLTSKLHKSEQEVNSLAAKVEELKQSHKLEVTNVKLEAARTKNEVERERNKIQSEMDGLLSDKEVLKEAVERHKVLLVEKDQELVRKVQAAKEEVFGKIAALQDEKLELESRLAHLEKVKLEQDAWRQTEKDQYEEKLRVVQLAEESSKRELQCLRLKIQQQAIQTEELEEKKRERDDLKQQIQDMQLQVASLSQSENDLLEYNQKLKETVERLRQECQNARTQAEKAQLETEKTLEYKRIEWLEEKHMLTQRITEKEEKYNEVKNKLCRAAVAQKKRKTLNDNKQRRMQEKLQLLEAKIEELEKENQVLNRQNVSYEEYARLQKRLKDLQRRHNEFRSLILNPGIPSLNPISATSAPVPPPGPDVPFLFLQEEQHQRELSVLRKRLEDLETTQRKQLQELGPAGERLPARARRELTSSRGAEGAAVQSEDST", "length": 717, "header": "tr|E1BZA0-1|E1BZA0_CHICK Computationally mapped isoform of Centrosomal protein 83 OS=Gallus gallus OX=9031 GN=CEP83 PE=4 SV=1 CANONICAL=A0A8V0YE85-1" }, "locus": { "chromosome": "1", "start_pos": 45204178, "end_pos": 45185760, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010025198.1", "url": "https://www.ensembl.org/id/ENSGALT00010025198.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010014283.1", "url": "https://www.ensembl.org/id/ENSGALP00010014283.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:417904", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417904", "resource": "KEGG Pathway" }, { "id": "R-GGA-5620912", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5620912", "resource": "Reactome", "description": "Anchoring of the basal body to the plasma membrane" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0R4IVY9-1", "protein_name": "Centrosomal protein of 83 kDa", "gene_name": "cep83", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDKMNPPALGQASALFPDLEPPGGVGKATVLLGGSTGLTSSDMEFQKMLIDERMRCENHKTNYQTLKVEHTRLQDQYTRAQNELKRLLSDRQVTQEKQQLLLAELRGELLDKTRDLEELKLQVLTPQRLELLRAQVQQELEAPIRERFNKLQEEAENYRSEYNKLRYDLTFLKSEFDHQKEEHARVLEERRIRHEADVARLEHDKEDLATQLQSGDPARDGKRVEALLREKAQLHQRLRGLEAEVTELRAERNNSGAQAENVQRIQIRQLAESQAAVKALEAEKQSIRMQLDRTESELRLSQEQNTLLTGKLHKAEREINSLNSQVEEMKHTHKLELSNVKLECVRSKGELERERDMLQCQVEGLQSDIEVMKSALERNKELISEKEREMVRRVQAAREEEIHKMATLQEEKLELENRLSELEQQKALQEVTGNSQKEEWEERLRAAQLGEESVRKELQNLRTKVQQQGQQLEELETLKAENADLRQQIAELNLQVGTLSHSESELLDTNNRLRESLERVREDLRSARTQMERTQQEAERLVEERRVEWLEEKHKLQDIEAELREKYSQAKERLQRAAFAQKKRKTMTELKENKLKDKIQLLEAKIAELEIEASAEKKKSSYSEEHAQLSKRLRELQRRHNEFRRLLLGNQMTSSTPLAQSLLIPNESIFSNIQEEQHQRELCVLRRRLEELENSQQQQLEELAAPLDRDRERLSSPRDALPDLS", "length": 725 }, "evidence": [ { "id": "A0A8V0YE85", "url": "https://omabrowser.org/oma/group/A0A8V0YE85/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A3Q1NHE2-1", "protein_name": "Centrosomal protein 83", "gene_name": "CEP83", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MVVHSVTNMDAFPTIFPPGGDSELRHSQSELQKMLIDERLRCEHHKTNYQTLKAEHTRLQDEYIKSQNELKRVLNEKQTHQEKFQLLLEEVRGELVEKTKDLEEMKLQVLTPQKLELLRAQIQQELETPMRERFKNLDEEVEKYRAEYNKLRYEHTFLKSEFEHQKEEFARILEEEKIKHKSEIARLEEDKELLNQLHSVDPTRESNRMEQLVRAKAHLHQKLKSLEAEIAELRAEKENSSAQAENVQRIQVRQLAEMQATVRSLEAEKQSAKLQAERLEKELQSSNEQNTALTSKLHKAEREVNTLASKVKELKHSNKLEITDIKLEAARAKSELERERNKIQSELDGLQSDNEILKSAVEHHKALLVEKDRELIRKVQAAKEEGYQKLLELQDEKLELESRLADLEKMKVEHDVCRQSEKDQCEEKLRASQMAEESARRELQSIRLKLQQQIVDIENAEKEKKENSDLKQQISGLQIQVTSLAQSENELLNSNQILKEMVERLKQECRNLRSQAEKAQLEVEKALEEKQIQWLEEKHKLHERITDREEKYNQAKEKLQRAAIAQKKRKSLHENKLKRLQEKVEILEAKREELETENQVLNRQNVPFEEYTRLQKRLKDIQRRHNEFRSLILVPNIPPSASINPVSLQSSTVIPGMELSFPPHMQEEQHQRELSLLRKRLEELETTQRKQLEELGSPGE", "length": 700 }, "evidence": [ { "id": "A0A8V0YE85", "url": "https://omabrowser.org/oma/group/A0A8V0YE85/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "I3LFF2-1", "protein_name": "Centrosomal protein 83", "gene_name": "CEP83", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MVVSLLTNMDTFPTTFPPGGDSGMTDSQSEFQKVLIDERLRCEHHKANYQVLKTEHTRLQAEYTKSQNELKRLINEKQTHQEKFQLLLQELRGELIEKTKDLEEMKLQVLTPQKLELLRAQIQQELETPMRERFRNLDEEVEKYRAEYNKLRYEHTFLKSEFEHQKEKFARVLEEEKIKYQSEVARLEKDNEELHNQLFSADPTRDSKRVEQLIREKVHLHQKLKGLETEVAELRAEKENSGAQVESVQRIQVRQLAEMQATVRSLEAEKQSAKLQAERLEKELQASNEQNTTLISKLHKTEREVNTLTSKVKELKHSNKLEITDVKLEAARAKSELERERNKIQSELDGLQSDNEILKSAVEHHKMLLVEKDRELIRKVQAAKEEGYQKLVALQDEKLELESRLADLEKMKLEHDVWRQSEKDQCEEKLRASQMAEESARRELQSIRLKLQQQIVNIENAEKEKKENSDLKQQISRLQIQVTSLAQSENELLNSNQILKEMVEELKQECRNLRSQSEKARLEVEKALEEKQKHWLEEKHKLHERITDREEKYNQAKEKLQRAAIAQKKRKSLHENKLKRLQEKVEVLEAKREELETENQVLNRQNVPFEEYTRLQKRLKDIQRRHNEFRSLILVPNIPPTASLNPVSFHSSNVIPGMELSFPPHIQEEQHQRELSLLRKRLEELETTQRKQLEELGSPGE", "length": 701 }, "evidence": [ { "id": "A0A8V0YE85", "url": "https://omabrowser.org/oma/group/A0A8V0YE85/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q66H89-1", "protein_name": "Centrosomal protein of 83 kDa", "gene_name": "Cep83", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDTFPSIFPPGGDSRLNPEPEFQSMLIDERVRCEHHKHNYQALKIEHKRLQEEYVKSQNELKRVLNEKQTNQEKFQLLLEELRGELVEKVKDMEAMKLQILTPQKLELVKAQLQQELEAPMRERFRTLDEEVERYRAEYNKLRYEHTFLKSEFEHQKEELTRISEEEKMKYKSEVARLEKDKEELHNQLLSVDPTRDSKRVEQLVREKTHLLQKLKSLEAEVAELRAEKENSGAQVENVQRIQVRQLAEMQATLRSLEAEKQSAKLQAERLEKELQSSNEQNTCLISKLHKADREISTLTSQVKELKHANKLEITDVKLEAARAKSELERERNKIQSELDGLQSDNEILKSTVEHHKVLLVEKDRELIRKVQAAKEEGYQKLVVLQDEKLELENRLSDLEKMKVEHDVWRQSEKDQCEEKLRASQAAEEAARRELQSIRLKLQQQIVNTEKAEKEKLENSELKQQISHLQIQVTSLTQSENDLLNSNQMLKDMVERLKQECRHLRSQAEKVQLEVEKTLEEKQIQWLEEKHKLHERITDREEKYNQAKEKLQRAATAQKKRKSLHENKLKRLQEKVEVLEAKKEELETENQVLNRQNVPFEEYTRLQKRLKDIQRRHNEFRSLILVPNMPPAASVNPANFQSSAIVPGVELSFPPHLQEEQHQRELSLLRKRLEELETTQRKQLEELGSPGE", "length": 692 }, "evidence": [ { "id": "A0A8V0YE85", "url": "https://omabrowser.org/oma/group/A0A8V0YE85/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9D5R3-1", "protein_name": "Centrosomal protein of 83 kDa", "gene_name": "Cep83", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDTFPSLFPPGGDSRLNPEPEFQNMLIDERVRCEHHKHNYQALKIEHKRLQEEYVKSQNELKRVLIEKQASQEKFQLLLEDLRGELVEKARDIEKMKLQVLTPQKLELVKAQLQQELEAPMRERFRTLDEEVERYRAEYNKLRYEYTFLKSEFEHQKEEFTRVSEEEKMKYKSEVARLEKDKEELHNQLLSVDPTRDSKRMEQLVREKTHLLQKLKSLEAEVAELRAEKENSGAQVENVQRIQVRQLAEMQATLRSLEAEKQSAKLQAERLEKELQSSNEQNTCLISKLHRADREISTLASEVKELKHANKLEITDIKLEAARAKSELERERNKIQSELDGLQSDNEILKSTVEHHKALLVEKDRELIRKVQAAKEEGYQKLMVLQDEKLELENRLSDLEKMKVERDVWRQSEKEQCEEKLRASQMAEEAARRELQSTRLKLQQQIVNTEKAEKEKLENSELKQQISHLQIQVTSLTQSENDLLNSNHMLKDMVERLKQECRNLRSQAEKAQLDVEKTLEEKQIQWLEEKHKLHERITDREEKYNQAKEKLQRAATAQKKRKSLHENKLKRLQEKVEVLEAKKEELETENQVLNRQNVPFEEYTRLQKRLKDIQRRHNEFRSLILVPNMPPTASISPANFQSAVTVPGAELSFPPHLQEEQHQRELSLLRKRLEELETTQRKQLEELGSPGE", "length": 692 }, "evidence": [ { "id": "A0A8V0YE85", "url": "https://omabrowser.org/oma/group/A0A8V0YE85/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9Y592-1", "protein_name": "Centrosomal protein of 83 kDa", "gene_name": "CEP83", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVVSTFTDMDTFPNNFPPGGDSGLTGSQSEFQKMLIDERLRCEHHKANYQTLKAEHTRLQNEHVKLQNELKHLFNEKQTQQEKLQLLLEELRGELVEKTKDLEEMKLQILTPQKLELLRAQIQQELETPMRERFRNLDEEVEKYRAVYNKLRYEHTFLKSEFEHQKEEYARILDEGKIKYESEIARLEEDKEELRNQLLNVDLTKDSKRVEQLAREKVYLCQKLKGLEAEVAELKAEKENSEAQVENAQRIQVRQLAEMQATVRSLEAEKQSANLRAERLEKELQSSSEQNTFLINKLHKAEREINTLSSKVKELKHSNKLEITDIKLETARAKSELERERNKIQSELDGLQSDNEILKAAVEHHKVLLVEKDRELIRKVQAAKEEGYQKLVVLQDEKLELENRLADLEKMKVEHDVWRQSEKDQYEEKLRASQMAEEITRKELQSVRLKLQQQIVTIENAEKEKNENSDLKQQISSLQIQVTSLAQSENDLLNSNQMLKEMVERLKQECRNFRSQAEKAQLEAEKTLEEKQIQWLEEKHKLHERITDREEKYNQAKEKLQRAAIAQKKRKSLHENKLKRLQEKVEVLEAKKEELETENQVLNRQNVPFEDYTRLQKRLKDIQRRHNEFRSLILVPNMPPTASINPVSFQSSAMVPSMELPFPPHMQEEQHQRELSLLRKRLEELETTQRKQLEELGSSGE", "length": 701 }, "evidence": [ { "id": "A0A8V0YE85", "url": "https://omabrowser.org/oma/group/A0A8V0YE85/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YE85", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE85" } ], "pmid": "" }, { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YE85", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE85" } ], "pmid": "" }, { "name": "centriole", "id": "GO:0005814", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005814", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YE85", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE85" } ], "pmid": "" }, { "name": "ciliary transition fiber", "id": "GO:0097539", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097539", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YE85", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE85" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "cilium assembly", "id": "GO:0060271", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060271", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YE85", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE85" } ], "pmid": "" }, { "name": "vesicle docking", "id": "GO:0048278", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048278", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YE85", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE85" } ], "pmid": "" }, { "name": "establishment of centrosome localization", "id": "GO:0051660", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051660", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YE85", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE85" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 643, "end_pos": 645, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 643, "end_pos": 645 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", 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"field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YEA9-1", "uniprot_ac": "A0A8V0YEA9", "uniprot_id": "A0A8V0YEA9_CHICK", "mass": { "chemical_mass": 114268.0, "monoisotopic_mass": 114268.0 }, "refseq": { "ac": "XP_040551841", "name": "ribonucleases P/MRP protein subunit POP1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040551841" }, "gene_names": [ { "name": "POP1", "type": "recommended", "evidence": [ { "id": "A0A8V0YEA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEA9" } ] }, { "name": "POP1", "type": "synonym", "evidence": [ { "id": "XP_040551841", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040551841" } ] } ], "protein_names": [ { "name": "POP1 homolog, ribonuclease P/MRP subunit", "type": "synonym", "evidence": [ { "id": "A0A8V0YEA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEA9/entry#names_and_taxonomy" } ] }, { "name": "ribonucleases P/MRP protein subunit POP1", "type": "synonym", "evidence": [ { "id": "XP_040551841", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040551841" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052533.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040551841", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040551841" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YEA9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEA9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "POP1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEA9", "locus": { "chromosome": "2", "start_pos": 127107596, "end_pos": 127086247, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010011673", "url": "https://www.ensembl.org/id/ENSGALG00010011673" } ] } } ], "crossref": [ { "id": "A0A8V0YEA9", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YEA9", "database": "AlphaFoldDB", "categories": [] }, { "id": "425567", "url": "https://www.ncbi.nlm.nih.gov/gene/425567", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR009723", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009723", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012590", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012590", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039182", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039182", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055079", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055079", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "KALSPMC", "url": "https://omabrowser.org/oma/group/KALSPMC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YAL6", "url": "https://www.orthodb.org/?gene=A0A8V0YAL6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YEA9", "url": "https://www.orthodb.org/?gene=A0A8V0YEA9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22731", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22731", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22731:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22731:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF06978", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06978", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08170", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08170", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF22770", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22770", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_040551841", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040551841", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YAL6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAL6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YAL6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAL6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YEA9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEA9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YEA9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEA9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSAAREKKRARKMRNQPASVTLPAEPGSFPGGGGGSGRACSAPGDVRSEQQYQQQRFLHQSVGPPYRKDQNRGDSRGRGRGGWQGEHQSSSEEMPRYITVSTFAQARAAEIKAMLKAVAQKSSNSLVFQTLPRHVRRRAMSHNIKRLPRRLQEVARKEAEKAVHQKKEQSKTKCRKARRRHVNLVAEFNCRQRKNIWLETHIWHAKRFHMVKKWGYCLGNSPTEKCYRACYRAMTNHCLLQDLSYYCCLELTGKENELLKQLARICSVDAGLTFGAANCLSGRFQGSLNLYRADHYPEEMLGPVTFIWKPKHGSENRQLWIWMHPALKQDILNELKAIFQCSEPQEVCIPEPITTLNQEEKQMDVVQRLGKKRKKEDKEGDKAVPVKKIIGDGTRDPLQSYSWVSQTTGIVISDRTMEILRYRLIGPLSHSVLTETLKAASIQTEMVDSESKLNNWWVENCKDSEKVSLHHRQTAIFELLEGISSPSAMPPGTILGLTVGDPRVNLPKKKTKAMPDPEKYQDNDKVRQLYLEGVPVECAHSFIWDQDICKNVTENKISEQELNKMRAQLLVPGSQLDLGPCESKIPILLVQQPGKMAGEDRPGWGSGWDIYLPKGWGMAFWIPFIYRGVRVGGLQEASKHSEYQRTPHTPDDFPDCPAGMQFAQELESSLLDKFKRRPPAKRANYIKLGTLSPFICPWGQLVKSWEGRMKASEEFVCPSSPHAEHCATEGHGFCDPKAEAEKEASPENGEVEETMEISSEDAMKTEGDPGTQDFGERGETMRSDFIVLRSEKLLMQLSAWCYPTCGKDRRPRLVSRLGGKEMTEEVLLPILMSYPRALVWVNLSLLRKGNPELHAMICIPTEDDLVHLSKDRLFCGPQEPKHRDVFKHKVQKLKEIKRKKKEEYNVKAQESNPPSVPEKETTEECKDLILGLWSGTLPDVISHCSRTLLGYVTRGDFSLATGCGEALGFVSLTGLLYMLHSQPADKKGIVLLRTPASLQYRFARLSIEV", "length": 1009, "header": "tr|A0A8V0YEA9-1|A0A8V0YEA9_CHICK Isoform 1 of POP1 homolog, ribonuclease P/MRP subunit OS=Gallus gallus OX=9031 GN=POP1 PE=4 SV=1 CANONICAL=A0A8V0YEA9-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YAL6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEA9/entry#A0A8V0YAL6-1", "sequence": { "sequence": "MSAAREKKRARKMRNQPASVTLPAEPGSFPGGGGGSGRACSAPGDVRSEQQYQQQRFLHQSVGPPYRKDQNRGDSRGRGRGGWQGEHQSSSEEMPRYITVSTFAQARAAEIKAMLKAVAQKSSNSLVFQTLPRHVRRRAMSHNIKRLPRRLQEVARKEAEKAVHQKKEQSKTKCRKARRRHVNLVAEFNCRQRKNIWLETHIWHAKRFHMVKKWGYCLGNSPTEKCYRACYRAMTNHCLLQDLSYYCCLELTGKENELLKQLARICSVDAGLTFGAANCLSGRFQGSLNLYRADHYPEEMLGPVTFIWKPKHGSENRQLWIWMHPALKQDILNELKAIFQCSEPQEVCIPEPITTLNQEEKQMDVVQRLGKKRKKEDKEGDKAVPVKKIIGDGTRDPLQSYSWVSQTTGIVISDRTMEILRYRLIGPLSHSVLTETLKAASIQTEMVDSESKLNNWWVENCKDSEKVSLHHRQTAIFELLEGISSPSAMPPGTILGLTVGDPRVNLPKKKTKAMPDPEKYQDNDKVRQLYLEGVPVECAHSFIWDQDICKNVTENKISEQIYRGVRVGGLQEASKHSEYQRTPHTPDDFPDCPAGMQFAQELESSLLDKFKRRPPAKRANYIKLGTLSPFICPWGQLVKSWEGRMKASEEFVCPSSPHAEHCATEGHGFCDPKAEAEKEASPENGEVEETMEISSEDAMKTEGDPGTQDFGERGETMRSDFIVLRSEKLLMQLSAWCYPTCGKDRRPRLVSRLGGKEMTEEVLLPILMSYPRALVWVNLSLLRKGNPELHAMICIPTEDDLVHLSKDRLFCGPQEPKHRDVFKHKVQKLKEIKRKKKEEYNVKAQESNPPSVPEKETTEECKDLILGLWSGTLPDVISHCSRTLLGYVTRGDFSLATGCGEALGFVSLTGLLYMLHSQPADKKGIVLLRTPASLQYRFARLSIEV", "length": 945, "header": "tr|A0A8V0YAL6-1|A0A8V0YAL6_CHICK Computationally mapped isoform of POP1 homolog, ribonuclease P/MRP subunit OS=Gallus gallus OX=9031 GN=POP1 PE=4 SV=1 CANONICAL=A0A8V0YEA9-1" }, "locus": { "chromosome": "2", "start_pos": 127106457, "end_pos": 127086414, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027921.1", "url": "https://www.ensembl.org/id/ENSGALT00010027921.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016021.1", "url": "https://www.ensembl.org/id/ENSGALP00010016021.1" } ] } }, { "isoform_ac": "A0A8V0YEA9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEA9/entry#A0A8V0YEA9-1", "sequence": { "sequence": "MSAAREKKRARKMRNQPASVTLPAEPGSFPGGGGGSGRACSAPGDVRSEQQYQQQRFLHQSVGPPYRKDQNRGDSRGRGRGGWQGEHQSSSEEMPRYITVSTFAQARAAEIKAMLKAVAQKSSNSLVFQTLPRHVRRRAMSHNIKRLPRRLQEVARKEAEKAVHQKKEQSKTKCRKARRRHVNLVAEFNCRQRKNIWLETHIWHAKRFHMVKKWGYCLGNSPTEKCYRACYRAMTNHCLLQDLSYYCCLELTGKENELLKQLARICSVDAGLTFGAANCLSGRFQGSLNLYRADHYPEEMLGPVTFIWKPKHGSENRQLWIWMHPALKQDILNELKAIFQCSEPQEVCIPEPITTLNQEEKQMDVVQRLGKKRKKEDKEGDKAVPVKKIIGDGTRDPLQSYSWVSQTTGIVISDRTMEILRYRLIGPLSHSVLTETLKAASIQTEMVDSESKLNNWWVENCKDSEKVSLHHRQTAIFELLEGISSPSAMPPGTILGLTVGDPRVNLPKKKTKAMPDPEKYQDNDKVRQLYLEGVPVECAHSFIWDQDICKNVTENKISEQELNKMRAQLLVPGSQLDLGPCESKIPILLVQQPGKMAGEDRPGWGSGWDIYLPKGWGMAFWIPFIYRGVRVGGLQEASKHSEYQRTPHTPDDFPDCPAGMQFAQELESSLLDKFKRRPPAKRANYIKLGTLSPFICPWGQLVKSWEGRMKASEEFVCPSSPHAEHCATEGHGFCDPKAEAEKEASPENGEVEETMEISSEDAMKTEGDPGTQDFGERGETMRSDFIVLRSEKLLMQLSAWCYPTCGKDRRPRLVSRLGGKEMTEEVLLPILMSYPRALVWVNLSLLRKGNPELHAMICIPTEDDLVHLSKDRLFCGPQEPKHRDVFKHKVQKLKEIKRKKKEEYNVKAQESNPPSVPEKETTEECKDLILGLWSGTLPDVISHCSRTLLGYVTRGDFSLATGCGEALGFVSLTGLLYMLHSQPADKKGIVLLRTPASLQYRFARLSIEV", "length": 1009, "header": "tr|A0A8V0YEA9-1|A0A8V0YEA9_CHICK Isoform 1 of POP1 homolog, ribonuclease P/MRP subunit OS=Gallus gallus OX=9031 GN=POP1 PE=4 SV=1 CANONICAL=A0A8V0YEA9-1" }, "locus": { "chromosome": "2", "start_pos": 127106457, "end_pos": 127086414, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027928.1", "url": "https://www.ensembl.org/id/ENSGALT00010027928.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016025.1", "url": "https://www.ensembl.org/id/ENSGALP00010016025.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "D4AE75-1", "protein_name": "POP1 homolog, ribonuclease P/MRP subunit", "gene_name": "Pop1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSNAKERKHAKKMRSQPSNVTLSSGFVTERDGKRHFGGKPSQSQKQELHSGTSRQWQIKMSPHLLPESDANEQTSSKTMFKKKGGWKAGPEGTSQEIPKYITASTFAQARAAEISAMLKAVTQKSSNSLVFQTLPRHMRRRAMSHNVKRLPRRLQEMAKKEAEKAAHQKKEHSKNKCHKARRCHINRTLEFNRRQQKNIWLETHIWHAKRFHMVKRWGYCLGERPTAKSHRACYRAMTDLCLLQDLSYYCCLELKGKEEEILKALSQMCSIDTGLTFAAVHCLSGKRQGSLMLYRANKYPRDMLGPVTFIWKSRETPGDASEERQLWIWLHPTLKLAVLEEIKTTCQCSEPVKPSVCVPAPLLTPAQEDIQAGLADDKIGKKRKRRDDGENARRAKKTIGDGTGDPCQPRSWLSPTTGIVVSDLTMEMNRFRLVGPLSHCILTSALRAAPVHRGEEDAEETPHGWWTDTCRSPHGLSLHQRQEAVFQLLGGISSPAEIPAGTILGLTVRDPRVNLPPQRCRALPDPERYHVSEFICEEGMCTSSWSCAHWKPLSDHTDDPDNEQVKQLLLEGVPVECAHSFIWNQDICQSVTENKIVDQDLNRMRSELLVPGSQLVLGARESKIPILLIQQPGKVTGEDRLGWGSGWDILLPKGWGMAFWIPFIYRGARVGGLKEAAVHSQYKRSPNVPGDFPDCRAGVLFAEDQAKDLLEKYQRRPPAKRPNYVKLGTLAPFCCPWEQLTRDWESRIQTQEAAVIDSVPGAQETDPRRLGVPCVPKETCQLSNEASIAENQPRKPEVTGCQAQAGTEVALEQNASEDHAAATGSQLCVVRSRKLLKQLSSWCGPSSEVRRAPCRGQQELTRKACLSILADFPRALVWVSLSLLKKGSPEPHTMICVPSKEDLFQLSQDQCYHGPCESRHSDPFKSLILKEKEKKKKEKRQDGEQGASKGQAAGAPTAGQEARIQGLWSGPLPGLTSHCSRPLLGFVTHGDFSMAVGCGEALGFVSVTGLLEMLSSQSAAMRGLVLLRPPTSLQYRFARVTIEV", "length": 1044 }, "evidence": [ { "id": "A0A8V0YEA9", "url": "https://omabrowser.org/oma/group/A0A8V0YEA9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E1BF14-1", "protein_name": "POP1 homolog, ribonuclease P/MRP subunit", "gene_name": "POP1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSNAKERKHAKKMRNQPTNVTLSSGFVADSGVKHHNGGGKPFQSQKESHPGTSRQRQTRTTHRPLAESDVKEQPSSRVTFRKKGGWKAGPEGTSQEIPKYITASTFAQARAAEISAMLKAVTQTSSNSLVFQTLPRHMRRRAMSHNVKRLPRRLREIAQKEAEKAVHQKKEHSKNKCHKARRCHINRILEFNRRQKKNKWLETHIWHAKRFHMVKRWGYCLGERPTVKSHRACYRAMTSRCLLQDLSYYCCLELEGKEEEILKALSSMCSIDTGLTFAAVHCLSGKCQGSVMLYRANKYPLEMLGPVTFMWKAQGTPGDTSESRQLWIWLHPALKQDILEEIKAVCQCMEPTKATVQIPDPLLTPSQEKSQIDLPEEKVSKKRKRKDDGENAQPVKKVTGDGTRDPLQPYSWLSPATGIVIRDLTMEMNRFRLIGPLSHCILTEALKAASVHSEGEDTEKTPHRWWIETCKNPDSVSLHRRQEAVFELLGGITSPAEIPAGTILGLTVGDPRINLPQKRSKVLPNPEKCQDNEKVRQLLLEGVPVECSHSFLWNQDICKSVTENKISDQDLNRKRSELLVPGSQLFLGPHESKVPILLIQQPGKVTGHEQRGWGSGWDILLPKGWGMAFWIPFIYRGARVGGLKETLVHSQYKRSPNVPDDFPDCPAGVLFAEEQAKHLLEKYKRRPPAKRPNYVKLGTLAPFYCPWEQLTRDWESRVQAPEESSAASSPSGGESGSSRDGVPRVAEPGRTAQLSDDQGTPLCDSSGPEGVMDTDCPATMGTEEATSQSAASSPLCVLRSRRLLRQLSAWCGPRPGGRQATQRAGRGQQGLTGEACPAMLDAFPRALVWVRLALLGKGSPGPHTLICVPAEEDLLQLSRDWLYHGPQEPKHSDPFKSQIREQKEKKKLEKRLNQGRAASEGLAEGGPVAGPQPLTLGLWSGPLPVVTSHCSRVLLGFVTQGDFSMAVGCGEALGFVSLTGLLDMLSKQPGLDRGLVLLRPPASLQYRFARITIEV", "length": 1015 }, "evidence": [ { "id": "A0A8V0YEA9", "url": "https://omabrowser.org/oma/group/A0A8V0YEA9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1S0M3-1", "protein_name": "POP1 homolog, ribonuclease P/MRP subunit", "gene_name": "POP1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSNAKERKHAKKMRNQPTNVTLSSGFVADGGVKHHSGGGKPFQAQKDPHSGTSRQWHARTSHHALAESDAKEQSSSKVTFRKKGGWKAGPEGTSQDIPKYITASTFAQARAAEISAMLKAVTQKSSNSLVFQTLPRHMRRRAMSHNVKRLPRRLQEIAQKEAEKAVHQKKEHSKTKCHKARRCHMNRMLEFNRRQKKNIWLETHIWHAKRFHMVKRWGYCLGERPTAKSHRACYRAMTSRCLLQDLSYYCCLELKGKEEEILKALSPMCSIDTGLTFAAVHCLSGKRQGSLMLYRANKYPQEMLGPVTFIWKPQGTPADTSESRQLWIWLHPTLKQDILEEIKAACQCMEPTKSAVCIPDSLLTPSQEKGQTEKIGRKRKWEDDGENAEPIKKIIGDGTRDPLQPYSWLSPTTGIMISDFTMEMNRFRLIGPLSHAILTEALKAASVHTEGEDTEKTPHRWWIETCKNPDSVSLHHRQEGIFGLLGGITSPAEIPAGTVLGLTVGDPRINLPQKRSRVLPNPEKCQDNEKVRQLLLEGVPVECSHSFLWNPDICKSVTENKISDQDLNRKRSELLVPGSQLLLGPHESKVPILLIQQPGKATGDDQRGWGSGWDVLLPKGWGMAFWIPFIYRGARVGGLKETVMHSQYKGSPNVPGDFPDCPAGVQFAQEQAKNLLEKYTRRPPAKRPNYVKLGTLAPFCCPWEQLTRDWESRVQAREESPAIPSPGGEESGPRRDVVPCAPTAQRTLQLSDDAGTSLNDADMMDTDCPAPAGTKWVAGRGAPRSLLCVVRSRKLLRQLSAWCGDSRAAQRAPGRGQQDLTREACLSISDRFPRALVWVRLSLLSKGSPEPHTMICVPAEEDLLQLSRDRLYRGPQESKHSDPFKSKIRKQKEQKKREKRQSPGPAAAEGLAEGDPPGHQALTLGLWSGPLPVVTSHCSRVLLGFVTQGDFSMAVGCGAALGFVSLTGLLDMLSSQPGAERGLVLLRPPASLQYRFARIAIEV", "length": 1003 }, "evidence": [ { "id": "A0A8V0YEA9", "url": "https://omabrowser.org/oma/group/A0A8V0YEA9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q99575-1", "protein_name": "Ribonucleases P/MRP protein subunit POP1", "gene_name": "POP1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSNAKERKHAKKMRNQPTNVTLSSGFVADRGVKHHSGGEKPFQAQKQEPHPGTSRQRQTRVNPHSLPDPEVNEQSSSKGMFRKKGGWKAGPEGTSQEIPKYITASTFAQARAAEISAMLKAVTQKSSNSLVFQTLPRHMRRRAMSHNVKRLPRRLQEIAQKEAEKAVHQKKEHSKNKCHKARRCHMNRTLEFNRRQKKNIWLETHIWHAKRFHMVKKWGYCLGERPTVKSHRACYRAMTNRCLLQDLSYYCCLELKGKEEEILKALSGMCNIDTGLTFAAVHCLSGKRQGSLVLYRVNKYPREMLGPVTFIWKSQRTPGDPSESRQLWIWLHPTLKQDILEEIKAACQCVEPIKSAVCIADPLPTPSQEKSQTELPDEKIGKKRKRKDDGENAKPIKKIIGDGTRDPCLPYSWISPTTGIIISDLTMEMNRFRLIGPLSHSILTEAIKAASVHTVGEDTEETPHRWWIETCKKPDSVSLHCRQEAIFELLGGITSPAEIPAGTILGLTVGDPRINLPQKKSKALPNPEKCQDNEKVRQLLLEGVPVECTHSFIWNQDICKSVTENKISDQDLNRMRSELLVPGSQLILGPHESKIPILLIQQPGKVTGEDRLGWGSGWDVLLPKGWGMAFWIPFIYRGVRVGGLKESAVHSQYKRSPNVPGDFPDCPAGMLFAEEQAKNLLEKYKRRPPAKRPNYVKLGTLAPFCCPWEQLTQDWESRVQAYEEPSVASSPNGKESDLRRSEVPCAPMPKKTHQPSDEVGTSIEHPREAEEVMDAGCQESAGPERITDQEASENHVAATGSHLCVLRSRKLLKQLSAWCGPSSEDSRGGRRAPGRGQQGLTREACLSILGHFPRALVWVSLSLLSKGSPEPHTMICVPAKEDFLQLHEDWHYCGPQESKHSDPFRSKILKQKEKKKREKRQKPGRASSDGPAGEEPVAGQEALTLGLWSGPLPRVTLHCSRTLLGFVTQGDFSMAVGCGEALGFVSLTGLLDMLSSQPAAQRGLVLLRPPASLQYRFARIAIEV", "length": 1024 }, "evidence": [ { "id": "A0A8V0YEA9", "url": "https://omabrowser.org/oma/group/A0A8V0YEA9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleolar ribonuclease P complex", "id": "GO:0005655", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005655", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YEA9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEA9" } ], "pmid": "" }, { "name": "ribonuclease MRP complex", "id": "GO:0000172", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000172", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YEA9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEA9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "tRNA decay", "id": "GO:0016078", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016078", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YEA9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEA9" } ], "pmid": "" }, { "name": "tRNA processing", "id": "GO:0008033", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008033", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YEA9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEA9" } ], "pmid": "" }, { "name": "tRNA 5'-leader removal", "id": "GO:0001682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001682", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YEA9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEA9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "ribonuclease P activity", "id": "GO:0004526", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004526", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YEA9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEA9" } ], "pmid": "" }, { "name": "ribonuclease P RNA binding", "id": "GO:0033204", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033204", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YEA9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEA9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 551, "end_pos": 553, "annotation": "n_glycosylation_sequon" }, { "start_pos": 842, "end_pos": 844, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YEA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEA9" }, { "id": "PF22770", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22770" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "POP1 C-terminal", "eco_id": "ECO_0000259", "start_pos": 837, "end_pos": 1009, "start_aa": "Ala", "end_aa": "Val", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0YEA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEA9" }, { "id": "PF08170", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08170" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "POPLD", "eco_id": "ECO_0000259", "start_pos": 607, "end_pos": 698, "start_aa": "Gly", "end_aa": "Trp", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0YEA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEA9" }, { "id": "PF06978", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06978" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Pop1 N-terminal", "eco_id": "ECO_0000259", "start_pos": 103, "end_pos": 178, "start_aa": "Phe", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 551, "end_pos": 553 }, { "start_pos": 842, "end_pos": 844 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YEB8-1", "uniprot_ac": "A0A8V0YEB8", "uniprot_id": "A0A8V0YEB8_CHICK", "mass": { "chemical_mass": 282129.0, "monoisotopic_mass": 282129.0 }, "refseq": {}, "gene_names": [ { "name": "MAP1B", "type": "recommended", "evidence": [ { "id": "A0A8V0YEB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEB8" } ] } ], "protein_names": [ { "name": "Microtubule associated protein 1B", "type": "synonym", "evidence": [ { "id": "A0A8V0YEB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEB8/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YEB8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEB8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MAP1B", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEB8", "locus": { "chromosome": "Z", "start_pos": 25874389, "end_pos": 25945771, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010011681", "url": "https://www.ensembl.org/id/ENSGALG00010011681" } ] } } ], "crossref": [ { "id": "IPR026074", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026074", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056617", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056617", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057480", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057480", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y5X4", "url": "https://www.orthodb.org/?gene=A0A8V0Y5X4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YC46", "url": "https://www.orthodb.org/?gene=A0A8V0YC46", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YEB8", "url": "https://www.orthodb.org/?gene=A0A8V0YEB8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YJ13", "url": "https://www.orthodb.org/?gene=A0A8V0YJ13", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13843", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13843", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13843:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13843:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF23415", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23415", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25281", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25281", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0Y5X4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5X4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y5X4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5X4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YC46", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC46", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YC46-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC46-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YEB8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEB8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YEB8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEB8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJ13", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ13", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJ13-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ13-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLEKRRRGCAGSPPSSSSSSSSAGPCPAPSPYKSAAASPPALTPCRLRSRRRAALPSPLSAPEPRGGAGGAMATVVVEADSEPSCSLPNPAAPSPSLSHRFLDSKFYLLVVIGELVTEEHLRRAIANIERGIRSWDTNLIECNLDQELKLFVSRHSARFSPEVRGQKILHHRSDVLETVVLINPSDEAVSTEVRLMITDAARHKLLVLTGQCFENTGELILQSGSFSFQNFIEIFTDQEIGELLSTTHPANKASLTLFCPEEGDWKNSNLDRHNLQDFINIKLNSSSILPEMEGLSEFTEYLSESVEVPSPFDILEPPTSGGFLKLSKPCCYIFPGGRGDSALFAVNGFNMLINGGSERKSCFWKLIRHLDRVDSILLTHIGDDNLPGINSMLQRKIAELEEEQSQGSTTNSDWMKNLISPDLGVVFLNVPENLKNMDPSFRVKRSVEEACFTLQYLNKLSMKPEPLFRNVGNTIDPIILFQKMGVGKLEMYVLNPVKSSKEMQYFMHQWSGTSKDKAEFLLPNGQELDIPLSYFTSVSSLIVWHPANPAEKIIRVLFPGNSTQYNILEGLEKLKHLDFLKQPMVTQKDLTGNIASPAVKQAKLKQRTDSKESLKPAAKTPPSKTVRKESKEETLEPAKPSPALEKPQKLESKEKTPVKKEKAVKPETKTIVAEKDVTTKEEQLGKSETSEKQASEKQDVKPKVTKEKSVKKEVKAKPEEKKDEKEKPKKEVSKKEEKPLIKKEEKPKKEDIKKEVKKEVKKEEKKEAKKEVKKEAPPKEAKKEVKKEEKKEIKKEEKEVKKDIKKVPKEIKKTPTPSTEAKKPAAKPKPQKKEEPAKKEAVPAGKAKEKGKIKTVKKESKVSGAQTALAAVGAAATTVAAVAAAEITASGKELEAERSLMSSPEDLTKDFEELKAEEVETIKATRPQVALIEDELKLTGKEHKDAFEVQKEKLDNEGPAESSDEGITTTEAEGECEQTPEELEPVEKHRVDDIEKFEDEGTGLEESSEAGDYEEKAETEEAEERGEDEEEKTPLDATKPYMEEARRIHDYSDEIMSEADANIKDEKYTEKADYETSDERAEEDREEAVEKAETEETEEEEEDKAEDIRDEEETEKIEAEEDYVMAVVDKAAEAGEVEDKYGLLIITPTKRSEPQSPAVEPASSIHDETLPGGSESEATVSDEENREDQPEEFTATSGYTQSTIEISGEPTPMDEMSTPRDVMSDETNNEESESPSQEYVNITKYETSLYSQEFGRPKLSPLPDAFNGLSEGSKTEATEGKDYNASASTISPPSSLEEDKFCKSAFQDVYRQKESETAKLEIKETCPEDVDVTGKRSPAKSPADSLSPPSPVAKTPLGERSVNFSLTPNEIKVSTETASITALPSVHQEIAEEHCASPEDKTLEVASPSQSAAGSAGHTPYYQSPTDEKSSQLPSETSEKSSEAPVSVEFSEVKDESTRPRISPMDEPVPDSESPIEKVLSPLRSPPLIGSETSYDMFLSADVKSPTRDYESPSEGKPEKEKSPVQMSPASEASSVGLFQEKQDEKSMEFMVIKESFSLERKMEDTEPSSSQSSLVLDERKLTGDLSPTQIDISQFGSLKEDTKMSISEGTVSDKSATPVDEVVAEDTYSHIEGVASVSTASVATSSFPEPTTDDVSPSLHAEVGSPHSTEVDDSLSVSVVQTPTTFQETEMSPSKEECPRPMSISPPDFSPKTAKSRTPVHDHRSPEQSTMSVEFGQESPEQSLAMDFSRQSPEYPTAGTGIHHISENGPTEVDYSPSDIQEPTFARKISPVEHTSYSQEKDISEIISVSQIEASSSSSSAHTPSQVTSPLPEETFSGAVPPRDMSLHSFTSEKVQSLGEKLSPKSDLSPLTPRESSPLYSPTFPDSPPAVTEAVSPSHTSPLSLQVSSDKVFGYQAVTLQETLTKHSPEPLFSPEKEDSEKSSRSPEELSYSYEATEKTTRSPEDISYSYEAVGKSTRSPQATDYSYETTGKITRSPEATDYSYEMRGKMTRSPGDTDYSYDLTQKTTVSPGDTDYSYELTQKTTRSPGDTDYSYEMTRKTTRSPGDTDYSHDVIGKTTKSLDVTDYSYERIGKGTQSLDAMDSSYEAMGKTTESPETISYCYDTSGRTTRSPEATDYSFETEKATRSPEATSYSYEASAHFTPGKSLAESRQDVDLCLVSSCEYKHPKTELSPSFINPNPLEWFASEEQSQDQEKLLTQSGGAQPPSGGKQQGRQCDETPPTSVSESAPSQTDSDVPPETEECPSITADANIDSEDESETIPTDKTITYKHIDPPPVPMQDRSPSPRHPDVSMVDPEALPIDQNLGKPLKKDLKEKTKTKKTGTKTKSSSPVKKSDGKSKQVASPKPAAKDSLEKSSKTASPKKKESVEKASKNISTPEVKTRVEEKDKDTKNAVNTTASKSAKTATTGPGTTKSAKSTAVPPGPPVYLDLVYIPNHSNSKNVDVEFFKRVRSSYYVVSGNDAAAEEPSRAVLDSLLEGKAQWESNMQVTLIPTHDSEVMREWYQETHEKQQDLNIMVLASSSTVVMQDESFPACKIEL", "length": 2562, "header": "tr|A0A8V0YEB8-1|A0A8V0YEB8_CHICK Isoform 1 of Microtubule associated protein 1B OS=Gallus gallus OX=9031 GN=MAP1B PE=1 SV=1 CANONICAL=A0A8V0YEB8-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Y5X4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEB8/entry#A0A8V0Y5X4-1", "sequence": { "sequence": "MLEKRRRGCAGSPPSSSSSSSSAGPCPAPSPYKSAAASPPALTPCRLRSRRRAALPSPLSAPEPRGGAGGAMATVVVEADSEPSCSLPNPAAPSPSLSHRFLDSKFYLLVVIGELVTEEHLRRAIANIERGIRSWDTNLIECNLDQELKLFVSRHSARFSPEVRGQKILHHRSDVLETVVLINPSDEAVSTEVRLMITDAARHKLLVLTGQCFENTGELILQSGSFSFQNFIEIFTDQEIGELLSTTHPANKASLTLFCPEEGDWKNSNLDRHNLQDFINIKLNSSSILPEMEGLSEFTEYLSESVEVPSPFDILEPPTSGGFLKLSKPCCYIFPGGRGDSALFAVNGFNMLINGGSERKSCFWKLIRHLDRVDSILLTHIGDDNLPGINSMLQRKIAELEEEQSQGSTTNSDWMKNLISPDLGVVFLNVPENLKNMDPSFRVKRSVEEACFTLQYLNKLSMKPEPLFRNVGNTIDPIILFQKMGVGKLEMYVLNPVKSSKEMQYFMHQWSGTSKDKAEFLLPNGQELDIPLSYFTSVSSLIVWHPANPAEKIIRVLFPGNSTQYNILEGLEKLKHLDFLKQPMVTQKDLTGNIASPAVKQAKLKQRTDSKESLKPAAKTPPSKTVRKESKEETLEPAKPSPALEKPQKLESKEKTPVKKEKAVKPETKTIVAEKDVTTKEEQLGKSETSEKQASEKQDVKPKVTKEKSVKKEEKKEAKKEVKKEAPPKEAKKEVKKEEKKEIKKEEKEVKKDIKKVPKEIKKTPTPSTEAKKPAAKPKPQKKEEPAKKEAVPAGKAKEKGKIKTVKKESKVSGAQTALAAVGAAATTVAAVAAAEITASGKELEAERSLMSSPEDLTKDFEELKAEEVETIKATRPQVALIEDELKLTGKEHKDAFEVQKEKLDNEGPAESSDEGITTTEAEGECEQTPEELEPVEKHRVDDIEKFEDEGTGLEESSEAGDYEEKAETEEAEERGEDEEEKTPLDATKPYMEEARRIHDYSDEIMSEADANIKDEKYTEKADYETSDERAEEDREEAVEKAETEETEEEEEDKAEDIRDEEETEKIEAEEDYVMAVVDKAAEAGEVEDKYGLLIITPTKRSEPQSPAVEPASSIHDETLPGGSESEATVSDEENREDQPEEFTATSGYTQSTIEISGEPTPMDEMSTPRDVMSDETNNEESESPSQEYVNITKYETSLYSQEFGRPKLSPLPDAFNGLSEGSKTEATEGKDYNASASTISPPSSLEEDKFCKSAFQDVYRQKESETAKLEIKETCPEDVDVTGKRSPAKSPADSLSPPSPVAKTPLGERSVNFSLTPNEIKVSTETASITALPSVHQEIAEEHCASPEDKTLEVASPSQSAAGSAGHTPYYQSPTDEKSSQLPSETSEKSSEAPVSVEFSEVKDESTRPRISPMDEPVPDSESPIEKVLSPLRSPPLIGSETSYDMFLSADVKSPTRDYESPSEGKPEKEKSPVQMSPASEASSVGLFQEKQDEKSMEFMVIKESFSLERKMEDTEPSSSQSSLVLDERKLTGDLSPTQIDISQFGSLKEDTKMSISEGTVSDKSATPVDEVVAEDTYSHIEGVASVSTASVATSSFPEPTTDDVSPSLHAEVGSPHSTEVDDSLSVSVVQTPTTFQETEMSPSKEECPRPMSISPPDFSPKTAKSRTPVHDHRSPEQSTMSVEFGQESPEQSLAMDFSRQSPEYPTAGTGIHHISENGPTEVDYSPSDIQEPTFARKISPVEHTSYSQEKDISEIISVSQIEASSSSSSAHTPSQVTSPLPEETFSGAVPPRDMSLHSFTSEKVQSLGEKLSPKSDLSPLTPRESSPLYSPTFPDSPPAVTEAVSPSHTSPLSLQVSSDKVFGYQAVTLQETLTKHSPEPLFSPEKEDSEKSSRSPEELSYSYEATEKTTRSPEDISYSYEAVGKSTRSPQATDYSYETTGKITRSPEATDYSYEMRGKMTRSPGDTDYSYDLTQKTTVSPGDTDYSYELTQKTTRSPGDTDYSYEMTRKTTRSPGDTDYSHDVIGKTTKSLDVTDYSYERIGKGTQSLDAMDSSYEAMGKTTESPETISYCYDTSGRTTRSPEATDYSFETEKATRSPEATSYSYEASAHFTPGKSLAESRQDVDLCLVSSCEYKHPKTELSPSFINPNPLEWFASEEQSQDQEKLLTQSGGAQPPSGGKQQGRQCDETPPTSVSESAPSQTDSDVPPETEECPSITADANIDSEDESETIPTDKTITYKHIDPPPVPMQDRSPSPRHPDVSMVDPEALPIDQNLGKPLKKDLKEKTKTKKTGTKTKSSSPVKKSDGKSKQVASPKPAAKDSLEKSSKTASPKKKESVEKASKNISTPEVKTRVEEKDKDTKNAVNTTASKSAKTATTGPGTTKSAKSTAVPPGPPVYLDLVYIPNHSNSKNVDVEFFKRVRSSYYVVSGNDAAAEEPSRAVLDSLLEGKAQWESNMQVTLIPTHDSEVMREWYQETHEKQQDLNIMVLASSSTVVMQDESFPACKIEL", "length": 2512, "header": "tr|A0A8V0Y5X4-1|A0A8V0Y5X4_CHICK Computationally mapped isoform of Microtubule associated protein 1B OS=Gallus gallus OX=9031 GN=MAP1B PE=1 SV=1 CANONICAL=A0A8V0YEB8-1" }, "locus": { "chromosome": "Z", "start_pos": 25945643, "end_pos": 25878411, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027945.1", "url": "https://www.ensembl.org/id/ENSGALT00010027945.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016038.1", "url": "https://www.ensembl.org/id/ENSGALP00010016038.1" } ] } }, { "isoform_ac": "A0A8V0YC46-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEB8/entry#A0A8V0YC46-1", "sequence": { "sequence": "MATVVVEADSEPSCSLPNPAAPSPSLSHRFLDSKFYLLVVIGELVTEEHLRRAIANIERGIRSWDTNLIECNLDQELKLFVSRHSARFSPEVRGQKILHHRSDVLETVVLINPSDEAVSTEVRLMITDAARHKLLVLTGQCFENTGELILQSGSFSFQNFIEIFTDQEIGELLSTTHPANKASLTLFCPEEGDWKNSNLDRHNLQDFINIKLNSSSILPEMEGLSEFTEYLSESVEVPSPFDILEPPTSGGFLKLSKPCCYIFPGGRGDSALFAVNGFNMLINGGSERKSCFWKLIRHLDRVDSILLTHIGDDNLPGINSMLQRKIAELEEEQSQGSTTNSDWMKNLISPDLGVVFLNVPENLKNMDPSFRVKRSVEEACFTLQYLNKLSMKPEPLFRNVGNTIDPIILFQKMGVGKLEMYVLNPVKSSKEMQYFMHQWSGTSKDKAEFLLPNGQELDIPLSYFTSVSSLIVWHPANPAEKIIRVLFPGNSTQYNILEGLEKLKHLDFLKQPMVTQKDLTGNIASPAVKQAKLKQRTDSKESLKPAAKTPPSKTVRKESKEETLEPAKPSPALEKPQKLESKEKTPVKKEKAVKPETKTIVAEKDVTTKEEQLGKSETSEKQASEKQDVKPKVTKEKSVKKEVKAKPEEKKDEKEKPKKEVSKKEEKPLIKKEEKPKKEDIKKEVKKEVKKEEKKEAKKEVKKEAPPKEAKKEVKKEEKKEIKKEEKEVKKDIKKVPKEIKKTPTPSTEAKKPAAKPKPQKKEEPAKKEAVPAGKAKEKGKIKTVKKESKVSGAQTALAAVGAAATTVAAVAAAEITASGKELEAERSLMSSPEDLTKDFEELKAEEVETIKATRPQVALIEDELKLTGKEHKDAFEVQKEKLDNEGPAESSDEGITTTEAEGECEQTPEELEPVEKHRVDDIEKFEDEGTGLEESSEAGDYEEKAETEEAEERGEDEEEKTPLDATKPYMEEARRIHDYSDEIMSEADANIKDEKYTEKADYETSDERAEEDREEHSAVHSFSI", "length": 1025, "header": "tr|A0A8V0YC46-1|A0A8V0YC46_CHICK Computationally mapped isoform of Microtubule associated protein 1B OS=Gallus gallus OX=9031 GN=MAP1B PE=1 SV=1 CANONICAL=A0A8V0YEB8-1" }, "locus": { "chromosome": "Z", "start_pos": 25945430, "end_pos": 25880689, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027942.1", "url": "https://www.ensembl.org/id/ENSGALT00010027942.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016035.1", "url": "https://www.ensembl.org/id/ENSGALP00010016035.1" } ] } }, { "isoform_ac": "A0A8V0YEB8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEB8/entry#A0A8V0YEB8-1", "sequence": { "sequence": "MLEKRRRGCAGSPPSSSSSSSSAGPCPAPSPYKSAAASPPALTPCRLRSRRRAALPSPLSAPEPRGGAGGAMATVVVEADSEPSCSLPNPAAPSPSLSHRFLDSKFYLLVVIGELVTEEHLRRAIANIERGIRSWDTNLIECNLDQELKLFVSRHSARFSPEVRGQKILHHRSDVLETVVLINPSDEAVSTEVRLMITDAARHKLLVLTGQCFENTGELILQSGSFSFQNFIEIFTDQEIGELLSTTHPANKASLTLFCPEEGDWKNSNLDRHNLQDFINIKLNSSSILPEMEGLSEFTEYLSESVEVPSPFDILEPPTSGGFLKLSKPCCYIFPGGRGDSALFAVNGFNMLINGGSERKSCFWKLIRHLDRVDSILLTHIGDDNLPGINSMLQRKIAELEEEQSQGSTTNSDWMKNLISPDLGVVFLNVPENLKNMDPSFRVKRSVEEACFTLQYLNKLSMKPEPLFRNVGNTIDPIILFQKMGVGKLEMYVLNPVKSSKEMQYFMHQWSGTSKDKAEFLLPNGQELDIPLSYFTSVSSLIVWHPANPAEKIIRVLFPGNSTQYNILEGLEKLKHLDFLKQPMVTQKDLTGNIASPAVKQAKLKQRTDSKESLKPAAKTPPSKTVRKESKEETLEPAKPSPALEKPQKLESKEKTPVKKEKAVKPETKTIVAEKDVTTKEEQLGKSETSEKQASEKQDVKPKVTKEKSVKKEVKAKPEEKKDEKEKPKKEVSKKEEKPLIKKEEKPKKEDIKKEVKKEVKKEEKKEAKKEVKKEAPPKEAKKEVKKEEKKEIKKEEKEVKKDIKKVPKEIKKTPTPSTEAKKPAAKPKPQKKEEPAKKEAVPAGKAKEKGKIKTVKKESKVSGAQTALAAVGAAATTVAAVAAAEITASGKELEAERSLMSSPEDLTKDFEELKAEEVETIKATRPQVALIEDELKLTGKEHKDAFEVQKEKLDNEGPAESSDEGITTTEAEGECEQTPEELEPVEKHRVDDIEKFEDEGTGLEESSEAGDYEEKAETEEAEERGEDEEEKTPLDATKPYMEEARRIHDYSDEIMSEADANIKDEKYTEKADYETSDERAEEDREEAVEKAETEETEEEEEDKAEDIRDEEETEKIEAEEDYVMAVVDKAAEAGEVEDKYGLLIITPTKRSEPQSPAVEPASSIHDETLPGGSESEATVSDEENREDQPEEFTATSGYTQSTIEISGEPTPMDEMSTPRDVMSDETNNEESESPSQEYVNITKYETSLYSQEFGRPKLSPLPDAFNGLSEGSKTEATEGKDYNASASTISPPSSLEEDKFCKSAFQDVYRQKESETAKLEIKETCPEDVDVTGKRSPAKSPADSLSPPSPVAKTPLGERSVNFSLTPNEIKVSTETASITALPSVHQEIAEEHCASPEDKTLEVASPSQSAAGSAGHTPYYQSPTDEKSSQLPSETSEKSSEAPVSVEFSEVKDESTRPRISPMDEPVPDSESPIEKVLSPLRSPPLIGSETSYDMFLSADVKSPTRDYESPSEGKPEKEKSPVQMSPASEASSVGLFQEKQDEKSMEFMVIKESFSLERKMEDTEPSSSQSSLVLDERKLTGDLSPTQIDISQFGSLKEDTKMSISEGTVSDKSATPVDEVVAEDTYSHIEGVASVSTASVATSSFPEPTTDDVSPSLHAEVGSPHSTEVDDSLSVSVVQTPTTFQETEMSPSKEECPRPMSISPPDFSPKTAKSRTPVHDHRSPEQSTMSVEFGQESPEQSLAMDFSRQSPEYPTAGTGIHHISENGPTEVDYSPSDIQEPTFARKISPVEHTSYSQEKDISEIISVSQIEASSSSSSAHTPSQVTSPLPEETFSGAVPPRDMSLHSFTSEKVQSLGEKLSPKSDLSPLTPRESSPLYSPTFPDSPPAVTEAVSPSHTSPLSLQVSSDKVFGYQAVTLQETLTKHSPEPLFSPEKEDSEKSSRSPEELSYSYEATEKTTRSPEDISYSYEAVGKSTRSPQATDYSYETTGKITRSPEATDYSYEMRGKMTRSPGDTDYSYDLTQKTTVSPGDTDYSYELTQKTTRSPGDTDYSYEMTRKTTRSPGDTDYSHDVIGKTTKSLDVTDYSYERIGKGTQSLDAMDSSYEAMGKTTESPETISYCYDTSGRTTRSPEATDYSFETEKATRSPEATSYSYEASAHFTPGKSLAESRQDVDLCLVSSCEYKHPKTELSPSFINPNPLEWFASEEQSQDQEKLLTQSGGAQPPSGGKQQGRQCDETPPTSVSESAPSQTDSDVPPETEECPSITADANIDSEDESETIPTDKTITYKHIDPPPVPMQDRSPSPRHPDVSMVDPEALPIDQNLGKPLKKDLKEKTKTKKTGTKTKSSSPVKKSDGKSKQVASPKPAAKDSLEKSSKTASPKKKESVEKASKNISTPEVKTRVEEKDKDTKNAVNTTASKSAKTATTGPGTTKSAKSTAVPPGPPVYLDLVYIPNHSNSKNVDVEFFKRVRSSYYVVSGNDAAAEEPSRAVLDSLLEGKAQWESNMQVTLIPTHDSEVMREWYQETHEKQQDLNIMVLASSSTVVMQDESFPACKIEL", "length": 2562, "header": "tr|A0A8V0YEB8-1|A0A8V0YEB8_CHICK Isoform 1 of Microtubule associated protein 1B OS=Gallus gallus OX=9031 GN=MAP1B PE=1 SV=1 CANONICAL=A0A8V0YEB8-1" }, "locus": { "chromosome": "Z", "start_pos": 25945643, "end_pos": 25878411, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027943.1", "url": "https://www.ensembl.org/id/ENSGALT00010027943.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016036.1", "url": "https://www.ensembl.org/id/ENSGALP00010016036.1" } ] } }, { "isoform_ac": "A0A8V0YJ13-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEB8/entry#A0A8V0YJ13-1", "sequence": { "sequence": "MFFICFLVVTGQKILHHRSDVLETVVLINPSDEAVSTEVRLMITDAARHKLLVLTGQCFENTGELILQSGSFSFQNFIEIFTDQEIGELLSTTHPANKASLTLFCPEEGDWKNSNLDRHNLQDFINIKLNSSSILPEMEGLSEFTEYLSESVEVPSPFDILEPPTSGGFLKLSKPCCYIFPGGRGDSALFAVNGFNMLINGGSERKSCFWKLIRHLDRVDSILLTHIGDDNLPGINSMLQRKIAELEEEQSQGSTTNSDWMKNLISPDLGVVFLNVPENLKNMDPSFRVKRSVEEACFTLQYLNKLSMKPEPLFRNVGNTIDPIILFQKMGVGKLEMYVLNPVKSSKEMQYFMHQWSGTSKDKAEFLLPNGQELDIPLSYFTSVSSLIVWHPANPAEKIIRVLFPGNSTQYNILEGLEKLKHLDFLKQPMVTQKDLTGNIASPAVKQAKLKQRTDSKESLKPAAKTPPSKTVRKESKEETLEPAKPSPALEKPQKLESKEKTPVKKEKAVKPETKTIVAEKDVTTKEEQLGKSETSEKQASEKQDVKPKVTKEKSVKKEVKAKPEEKKDEKEKPKKEVSKKEEKPLIKKEEKPKKEDIKKEVKKEVKKEEKKEAKKEVKKEAPPKEAKKEVKKEEKKEIKKEEKEVKKDIKKVPKEIKKTPTPSTEAKKPAAKPKPQKKEEPAKKEAVPAGKAKEKGKIKTVKKESKVSGAQTALAAVGAAATTVAAVAAAEITASGKELEAERSLMSSPEDLTKDFEELKAEEVETIKATRPQVALIEDELKLTGKEHKDAFEVQKEKLDNEGPAESSDEGITTTEAEGECEQTPEELEPVEKHRVDDIEKFEDEGTGLEESSEAGDYEEKAETEEAEERGEDEEEKTPLDATKPYMEEARRIHDYSDEIMSEADANIKDEKYTEKADYETSDERAEEDREEAVEKAETEETEEEEEDKAEDIRDEEETEKIEAEEDYVMAVVDKAAEAGEVEDKYGLLIITPTKRSEPQSPAVEPASSIHDETLPGGSESEATVSDEENREDQPEEFTATSGYTQSTIEISGEPTPMDEMSTPRDVMSDETNNEESESPSQEYVNITKYETSLYSQEFGRPKLSPLPDAFNGLSEGSKTEATEGKDYNASASTISPPSSLEEDKFCKSAFQDVYRQKESETAKLEIKETCPEDVDVTGKRSPAKSPADSLSPPSPVAKTPLGERSVNFSLTPNEIKVSTETASITALPSVHQEIAEEHCASPEDKTLEVASPSQSAAGSAGHTPYYQSPTDEKSSQLPSETSEKSSEAPVSVEFSEVKDESTRPRISPMDEPVPDSESPIEKVLSPLRSPPLIGSETSYDMFLSADVKSPTRDYESPSEGKPEKEKSPVQMSPASEASSVGLFQEKQDEKSMEFMVIKESFSLERKMEDTEPSSSQSSLVLDERKLTGDLSPTQIDISQFGSLKEDTKMSISEGTVSDKSATPVDEVVAEDTYSHIEGVASVSTASVATSSFPEPTTDDVSPSLHAEVGSPHSTEVDDSLSVSVVQTPTTFQETEMSPSKEECPRPMSISPPDFSPKTAKSRTPVHDHRSPEQSTMSVEFGQESPEQSLAMDFSRQSPEYPTAGTGIHHISENGPTEVDYSPSDIQEPTFARKISPVEHTSYSQEKDISEIISVSQIEASSSSSSAHTPSQVTSPLPEETFSGAVPPRDMSLHSFTSEKVQSLGEKLSPKSDLSPLTPRESSPLYSPTFPDSPPAVTEAVSPSHTSPLSLQVSSDKVFGYQAVTLQETLTKHSPEPLFSPEKEDSEKSSRSPEELSYSYEATEKTTRSPEDISYSYEAVGKSTRSPQATDYSYETTGKITRSPEATDYSYEMRGKMTRSPGDTDYSYDLTQKTTVSPGDTDYSYELTQKTTRSPGDTDYSYEMTRKTTRSPGDTDYSHDVIGKTTKSLDVTDYSYERIGKGTQSLDAMDSSYEAMGKTTESPETISYCYDTSGRTTRSPEATDYSFETEKATRSPEATSYSYEASAHFTPGKSLAESRQDVDLCLVSSCEYKHPKTELSPSFINPNPLEWFASEEQSQDQEKLLTQSGGAQPPSGGKQQGRQCDETPPTSVSESAPSQTDSDVPPETEECPSITADANIDSEDESETIPTDKTITYKHIDPPPVPMQDRSPSPRHPDVSMVDPEALPIDQNLGKPLKKDLKEKTKTKKTGTKTKSSSPVKKSDGKSKQVASPKPAAKDSLEKSSKTASPKKKESVEKASKNISTPEVKTRVEEKDKDTKNAVNTTASKSAKTATTGPGTTKSAKSTAVPPGPPVYLDLVYIPNHSNSKNVDVEFFKRVRSSYYVVSGNDAAAEEPSRAVLDSLLEGKAQWESNMQVTLIPTHDSEVMREWYQETHEKQQDLNIMVLASSSTVVMQDESFPACKIEL", "length": 2408, "header": "tr|A0A8V0YJ13-1|A0A8V0YJ13_CHICK Computationally mapped isoform of Microtubule associated protein 1B OS=Gallus gallus OX=9031 GN=MAP1B PE=1 SV=1 CANONICAL=A0A8V0YEB8-1" }, "locus": { "chromosome": "Z", "start_pos": 25934476, "end_pos": 25878411, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027941.1", "url": "https://www.ensembl.org/id/ENSGALT00010027941.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016034.1", "url": "https://www.ensembl.org/id/ENSGALP00010016034.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 816, "start_aa": "Thr", "end_pos": 816, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr816", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 10, "go_terms": [ { "name": "glutamatergic synapse", "id": "GO:0098978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098978", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YEB8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEB8" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YEB8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEB8" } ], "pmid": "" }, { "name": "microtubule", "id": "GO:0005874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005874", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YEB8", "url": 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"sequence": "MSPAGKWQPLSLVFLLGMGMAAGDSSCPSGCSCRYLEVNCTGRQLQEFPTAIPLDTRQLILAANNVSYLPAVELSFLADLVYLDCQKNLLGDDLDFTFIGVVKLVYLDLSFNNLTQVTFSTFSQLLSLVVLKISDNPNLVAIEKDAFANNTWLRHLDVSRTGLTFLDASTVQDLPNLRFLGLSDNLWHCNCSFLDFITWMTESSVHFPDADNITCYTPEALRALKMPAAEVQLDSSCQTHLHKQDYIFLCFIGFCIFFAGTVVAWLAGICAVIYQIHSSKQEEEEEEEEKDAVT", "length": 294, "header": "tr|E1C2A3-1|E1C2A3_CHICK Computationally mapped isoform of Leucine rich repeat containing 52 OS=Gallus gallus OX=9031 GN=LRRC52 PE=4 SV=4 CANONICAL=A0A8V0YEC0-1" }, "locus": { "chromosome": "8", "start_pos": 5471651, "end_pos": 5469640, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010025266.1", "url": "https://www.ensembl.org/id/ENSGALT00010025266.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010014314.1", "url": "https://www.ensembl.org/id/ENSGALP00010014314.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2M9I3-1", "protein_name": "Leucine-rich repeat-containing protein 52", "gene_name": "Lrrc52", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSLASGPGPQLLLFSLGMGLVSGSKCPNNCLCQDQEVFCTNMQLMEYPLDIPLNTRRLFLSNNKITSLPALQLGLLSDLVYLDCQNNRIRELMDYTFIGVFKLIYLDLSSNNLTSISPFTFSVLSNLVRLNISNNPHLLYLNKYIFANTSSLRHLDLRNTGLQTIDHNALHHLMVLQTLYLSGNPWKCNCSFLDFTIHLLVSEIDQPDGQNATCMEPTELSGWPVAQVGNPLQYMCLTHLDHQDYIFLLLIGFCIFAAGTVAAWLTGVGAVLYQNARRKSGGDDTEDESGNRVTNQIFRSKANFSQGRFPHLI", "length": 313 }, "evidence": [ { "id": "A0A8V0YEC0", "url": "https://omabrowser.org/oma/group/A0A8V0YEC0/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0AAA9T502-1", "protein_name": "Leucine rich repeat containing 52", "gene_name": "LRRC52", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSLASDPRPGWLLFSFGMVLVSGSKCPNNCQCQDQEVICTGIQLTEYPSDIPLNTRRLYLNDNKIRFLPAMNLGLLSDLVYLDCQKNRIQEVMDYTFVGVFRLIYLDLSFNNLTFISPYSFSMLSNLLQLNISNNPHLLSLNKYTFANTSSLRYLDLRNTGLQTLDEAAFQNLITLQTLYLSGNPWKCNCFFLDFTIYLIVSHLNYPDEQNATCVEPTELAGWPITKVGNPLRYMCITNLDLQDYIFLLLISFCIFCAGTVAAWLTGVCAVLYQNACRKSSEDEVEEEEAENEDEQRVEVSRRIFHSRVDSGHDGFPQLI", "length": 320 }, "evidence": [ { "id": "A0A8V0YEC0", "url": "https://omabrowser.org/oma/group/A0A8V0YEC0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q5M8M9-1", "protein_name": "Leucine-rich repeat-containing protein 52", "gene_name": "Lrrc52", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSLASGPSSKLLLFSLGMGLVSGSKCPNKCVCQDQEVACIDLHLTEYPADIPLNTRRLYLNNNKITSLPALQLGFLSDLVYLDCQNNRIREVMDYTFIGIFRLIYLDLSSNNLTSISPFSFSVLTNLVRLNISHNPHLLYLDKYVFANTTSLRYLDLRNTGLHIIDHNGFHHLVVLQTLYLSGNPWICNCSFLDFTIHLLVSHMDHPDAQNATCTEPAELKGWPITKVGNPLQYMCITHLDQQDYIFLLLIGFCIFAAGTVAAWLTGVCAVLYQNALRTSSGDDTEDETGSRFANQIFRSNTHLGPIRRFPELI", "length": 314 }, "evidence": [ { "id": "A0A8V0YEC0", "url": "https://omabrowser.org/oma/group/A0A8V0YEC0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8N7C0-1", "protein_name": "Leucine-rich repeat-containing protein 52", "gene_name": "LRRC52", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSLASGPGPGWLLFSFGMGLVSGSKCPNNCLCQAQEVICTGKQLTEYPLDIPLNTRRLFLNENRITSLPAMHLGLLSDLVYLDCQNNRIREVMDYTFIGVFKLIYLDLSSNNLTSISPFTFSVLSNLVQLNIANNPHLLSLHKFTFANTTSLRYLDLRNTGLQTLDSAALYHLTTLETLFLSGNPWKCNCSFLDFAIFLIVFHMDPSDDLNATCVEPTELTGWPITRVGNPLRYMCITHLDHKDYIFLLLIGFCIFAAGTVAAWLTGVCAVLYQNTRHKSSEEDEDEAGTRVEVSRRIFQTQTSSVQEFPQLI", "length": 313 }, "evidence": [ { "id": "A0A8V0YEC0", "url": "https://omabrowser.org/oma/group/A0A8V0YEC0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "transmembrane transporter binding", "id": "GO:0044325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044325", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YEC0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEC0" } ], "pmid": "" }, { "name": "voltage-gated potassium channel activity", "id": "GO:0005249", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005249", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YEC0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEC0" } ], "pmid": "" }, { "name": "potassium channel activator activity", "id": "GO:0099104", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099104", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YEC0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEC0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "voltage-gated potassium channel complex", "id": "GO:0008076", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008076", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YEC0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEC0" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YEC0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEC0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "potassium ion transmembrane transport", "id": "GO:0071805", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071805", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YEC0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEC0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 113, "end_pos": 115, "annotation": "n_glycosylation_sequon" }, { "start_pos": 149, "end_pos": 151, "annotation": "n_glycosylation_sequon" }, { "start_pos": 190, "end_pos": 192, "annotation": "n_glycosylation_sequon" }, { "start_pos": 268, "end_pos": 270, "annotation": "n_glycosylation_sequon" }, { "start_pos": 39, "end_pos": 41, "annotation": "n_glycosylation_sequon" }, { "start_pos": 65, "end_pos": 67, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YEC0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEC0" }, { "id": "SM00013", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00013" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "LRRNT", "eco_id": "ECO_0000259", "start_pos": 26, "end_pos": 58, "start_aa": "Ser", "end_aa": "Gln", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 113, "end_pos": 115 }, { "start_pos": 149, "end_pos": 151 }, { "start_pos": 190, "end_pos": 192 }, { "start_pos": 268, "end_pos": 270 }, { "start_pos": 39, "end_pos": 41 }, { "start_pos": 65, "end_pos": 67 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YEC1-1", "uniprot_ac": "A0A8V0YEC1", "uniprot_id": "A0A8V0YEC1_CHICK", "mass": { "chemical_mass": 40505.0, "monoisotopic_mass": 40505.0 }, "refseq": {}, "gene_names": [ { "name": "CRYZL1", "type": "recommended", "evidence": [ { "id": "A0A8V0YEC1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEC1" } ] } ], "protein_names": [ { "name": "Crystallin zeta like 1", "type": "synonym", "evidence": [ { "id": "A0A8V0YEC1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEC1/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YEC1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEC1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CRYZL1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEC1", "locus": { "chromosome": "1", "start_pos": 105534497, "end_pos": 105555250, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012129", "url": "https://www.ensembl.org/id/ENSGALG00010012129" } ] } } ], "crossref": [ { "id": "A0A8V0YEC1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YEC1", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd05195", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05195", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "418505", "url": "https://www.ncbi.nlm.nih.gov/gene/418505", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011032", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011032", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013154", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013154", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020843", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020843", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036291", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036291", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042633", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042633", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:418505", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418505", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0Y830", "url": "https://www.orthodb.org/?gene=A0A8V0Y830", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y835", "url": "https://www.orthodb.org/?gene=A0A8V0Y835", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YEC1", "url": "https://www.orthodb.org/?gene=A0A8V0YEC1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YL94", "url": "https://www.orthodb.org/?gene=A0A8V0YL94", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR44461", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR44461", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR44461:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR44461:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF08240", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08240", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0Y830", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y830", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y830-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y830-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y835", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y835", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y835-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y835-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YEC1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEC1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YEC1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEC1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YL94", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL94", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YL94-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL94-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLAVCEVTMKALYCQQNSSGEEMTFIFQERENLPPTGDNDVKVQVRACALSWIDTKLLSEVKLEKELLPVGREISGVVLEVGRKVSFFQPDDEVAGILPLDSEESGLCEVVLVHEHYLVHKPEKVCWVEAAGTVRDGVRAYTALHYLSQVSPGKTVLVMDGASPFGTIAIQLAQHRGAKVISTAYSLEDKQYLERLRPAVEGMRQPLVTRVIDVSNGKIDVAESCLEETGGLGVDIVVDAGVKLYSAEDESTSKSQLLPHKHDIITLLGVGGNWITTERNLQLDPPDSHSLFLKGATVSFLNEEIWNLSNIEQGKYLCILEDIMEKLSSSVFRPQLDEPIPLYEAKVSMEIVQKNQARKRQVIQF", "length": 365, "header": "tr|A0A8V0YEC1-1|A0A8V0YEC1_CHICK Isoform 1 of Crystallin zeta like 1 OS=Gallus gallus OX=9031 GN=CRYZL1 PE=1 SV=1 CANONICAL=A0A8V0YEC1-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Y830-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEC1/entry#A0A8V0Y830-1", "sequence": { "sequence": "MVTMKALYCQQNSSGEEMTFIFQERENLPPTGDNDVKVQVRACALSWIDTKLLSEVKLEKELLPVGREISGVVLEVGRKVSFFQPDDEVAGILPLDSEESGLCEVVLVHEHYLVHKPEKVCWVEAAGTVRDGVRAYTALHYLSQVSPGKTVLVMDGASPFGTIAIQLAQHRGAKVISTAYSLEDKQYLERLRPAVGMRQPLVTRVIDVSNGKIDVAESCLEETGGLGVDIVVDAGVKLYSAEDESTSKSQLLPHKHDIITLLGVGGNWITTERNLQLDPPDSHSLFLKGATVSFLNEEIWNLSNIEQGKYLCILEDIMEKLSSSVFRPQLDEPIPLYEAKVSMEIVQKNQARKRQVIQF", "length": 359, "header": "tr|A0A8V0Y830-1|A0A8V0Y830_CHICK Computationally mapped isoform of Crystallin zeta like 1 OS=Gallus gallus OX=9031 GN=CRYZL1 PE=1 SV=1 CANONICAL=A0A8V0YEC1-1" }, "locus": { "chromosome": "1", "start_pos": 105554173, "end_pos": 105534833, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029090.1", "url": "https://www.ensembl.org/id/ENSGALT00010029090.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016849.1", "url": "https://www.ensembl.org/id/ENSGALP00010016849.1" } ] } }, { "isoform_ac": "A0A8V0Y835-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEC1/entry#A0A8V0Y835-1", "sequence": { "sequence": "MKALYCQQNSSGEEMTFIFQERENLPPTGDNDVKVQVRACALSWIDTKLLSEVKLEKELLPVGREISGVVLEVGRKVSFFQPDDEVAGILPLDSEESGLCEVVLVHEHYLVHKPEKVCWVEAAGTVRDGVRAYTALHYLSQVSPGKTVLVMDGASPFGTIAIQLAQHRGAKVISTAYSLEDKQYLERLRPAVEGMRQPLVTRVIDVSNGKIDVAESCLEETGGLGVDIVVDAGVKLYSAEDESTSKSQLLPHKHDIITLLGVGGNWITTERNLQLDPPDSHSLFLKGATVSFLNEEIWNLSNIEQGKYLYTHLRRYNGEIIK", "length": 322, "header": "tr|A0A8V0Y835-1|A0A8V0Y835_CHICK Computationally mapped isoform of Crystallin zeta like 1 OS=Gallus gallus OX=9031 GN=CRYZL1 PE=1 SV=1 CANONICAL=A0A8V0YEC1-1" }, "locus": { "chromosome": "1", "start_pos": 105553982, "end_pos": 105535595, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029098.1", "url": "https://www.ensembl.org/id/ENSGALT00010029098.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016857.1", "url": "https://www.ensembl.org/id/ENSGALP00010016857.1" } ] } }, { "isoform_ac": "A0A8V0YEC1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEC1/entry#A0A8V0YEC1-1", "sequence": { "sequence": "MLAVCEVTMKALYCQQNSSGEEMTFIFQERENLPPTGDNDVKVQVRACALSWIDTKLLSEVKLEKELLPVGREISGVVLEVGRKVSFFQPDDEVAGILPLDSEESGLCEVVLVHEHYLVHKPEKVCWVEAAGTVRDGVRAYTALHYLSQVSPGKTVLVMDGASPFGTIAIQLAQHRGAKVISTAYSLEDKQYLERLRPAVEGMRQPLVTRVIDVSNGKIDVAESCLEETGGLGVDIVVDAGVKLYSAEDESTSKSQLLPHKHDIITLLGVGGNWITTERNLQLDPPDSHSLFLKGATVSFLNEEIWNLSNIEQGKYLCILEDIMEKLSSSVFRPQLDEPIPLYEAKVSMEIVQKNQARKRQVIQF", "length": 365, "header": "tr|A0A8V0YEC1-1|A0A8V0YEC1_CHICK Isoform 1 of Crystallin zeta like 1 OS=Gallus gallus OX=9031 GN=CRYZL1 PE=1 SV=1 CANONICAL=A0A8V0YEC1-1" }, "locus": { "chromosome": "1", "start_pos": 105554569, "end_pos": 105534833, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029094.1", "url": "https://www.ensembl.org/id/ENSGALT00010029094.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016853.1", "url": "https://www.ensembl.org/id/ENSGALP00010016853.1" } ] } }, { "isoform_ac": "A0A8V0YL94-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEC1/entry#A0A8V0YL94-1", "sequence": { "sequence": "MLAVCEVTMKALYCQQNSSGEEMTFIFQERENLPPTGDNDVKVQVRACALSWIDTKLLSEVKLEKELLPVGREISGVVLEVGRKVSFFQPDDEVAGILPLDSEESGLCEVVLVHEHYLVHKPEKVCWVEAAGTVRDGVRAYTALHYLSQVSPGKTVLVMDGASPFGTIAIQLAQHRGAKVISTAYSLEDKQYLERLRPAVARVIDVSNGKIDVAESCLEETGGLGVDIVVDAGVKLYSAEDESTSKSQLLPHKHDIITLLGVGGNWITTERNLQLDPPDSHSLFLKGATVSFLNEEIWNLSNIEQGKYLCILEDIMEKLSSSVFRPQLDEPIPLYEAKVSMEIVQKNQARKRQVIQF", "length": 357, "header": "tr|A0A8V0YL94-1|A0A8V0YL94_CHICK Computationally mapped isoform of Crystallin zeta like 1 OS=Gallus gallus OX=9031 GN=CRYZL1 PE=1 SV=1 CANONICAL=A0A8V0YEC1-1" }, "locus": { "chromosome": "1", "start_pos": 105554569, "end_pos": 105534833, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029092.1", "url": "https://www.ensembl.org/id/ENSGALT00010029092.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016851.1", "url": "https://www.ensembl.org/id/ENSGALP00010016851.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:418505", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418505", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "early endosome", "id": "GO:0005769", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005769", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YEC1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEC1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YEC1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEC1" } ], "pmid": "" }, { "name": "oxidoreductase activity", "id": "GO:0016491", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016491", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YEC1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEC1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 17, "end_pos": 19, "annotation": "n_glycosylation_sequon" }, { "start_pos": 307, "end_pos": 309, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YEC1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEC1" }, { "id": "SM00829", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00829" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Enoyl reductase (ER)", "eco_id": "ECO_0000259", "start_pos": 20, "end_pos": 363, "start_aa": "Gly", "end_aa": "Ile", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 17, "end_pos": 19 }, { "start_pos": 307, "end_pos": 309 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YEC3-1", "uniprot_ac": "A0A8V0YEC3", "uniprot_id": "A0A8V0YEC3_CHICK", "mass": { "chemical_mass": 41006.0, "monoisotopic_mass": 41006.0 }, "refseq": {}, "gene_names": [ { "name": "NIPAL2", "type": "recommended", "evidence": [ { "id": "A0A8V0YEC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEC3" } ] } ], "protein_names": [ { "name": "NIPA like domain containing 2", "type": "synonym", "evidence": [ { "id": "A0A8V0YEC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEC3/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YEC3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEC3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "NIPAL2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEC3", "locus": { "chromosome": "2", "start_pos": 127123381, "end_pos": 127177583, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010011683", "url": "https://www.ensembl.org/id/ENSGALG00010011683" } ] } } ], "crossref": [ { "id": "A0A8V0YEC3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YEC3", "database": "AlphaFoldDB", "categories": [] }, { "id": "771428", "url": "https://www.ncbi.nlm.nih.gov/gene/771428", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR008521", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008521", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037185", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037185", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:771428", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:771428", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HLQQSFI", "url": "https://omabrowser.org/oma/group/HLQQSFI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YEC3", "url": "https://www.orthodb.org/?gene=A0A8V0YEC3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YJ19", "url": "https://www.orthodb.org/?gene=A0A8V0YJ19", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12570", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12570", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12570:SF16", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12570:SF16", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05653", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05653", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YEC3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEC3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YEC3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEC3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJ19", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ19", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJ19-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ19-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQSSPTGSPSRAAALLQEQAVVVWSCPAGHWRVGQLHSLWICPHCPCCSTRMCIYHRKPTYGDNRTLPLSEENQHLTNLCVAPLHLSLKALNCIPCSKWTFPIIFFNLNGNSHAVVIDSSAFISVIFLKKTMRAADILGGALAVVGTYLLVTFAPNVSQQLTARQVQNDLVSWPFLVYVILEIIIFCILLYFYKRKAVKHIVVLLMMVALLASLTVIAVKAVASMIILSAKGKMQLTYPVFYIMLILMATSCVFQVKFLNQALHLYEARAVVPINFVFCTTSAIISGVIFYQEFQSAAFLSVFMFLFGCLLSFLSVFVIAVNKNEERLQVPYIDCGCIPGQKLTGKIQPDSYGSCYGTLNNKDDSGKSQS", "length": 370, "header": "tr|A0A8V0YEC3-1|A0A8V0YEC3_CHICK Isoform 1 of NIPA like domain containing 2 OS=Gallus gallus OX=9031 GN=NIPAL2 PE=3 SV=1 CANONICAL=A0A8V0YEC3-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YEC3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEC3/entry#A0A8V0YEC3-1", "sequence": { "sequence": "MQSSPTGSPSRAAALLQEQAVVVWSCPAGHWRVGQLHSLWICPHCPCCSTRMCIYHRKPTYGDNRTLPLSEENQHLTNLCVAPLHLSLKALNCIPCSKWTFPIIFFNLNGNSHAVVIDSSAFISVIFLKKTMRAADILGGALAVVGTYLLVTFAPNVSQQLTARQVQNDLVSWPFLVYVILEIIIFCILLYFYKRKAVKHIVVLLMMVALLASLTVIAVKAVASMIILSAKGKMQLTYPVFYIMLILMATSCVFQVKFLNQALHLYEARAVVPINFVFCTTSAIISGVIFYQEFQSAAFLSVFMFLFGCLLSFLSVFVIAVNKNEERLQVPYIDCGCIPGQKLTGKIQPDSYGSCYGTLNNKDDSGKSQS", "length": 370, "header": "tr|A0A8V0YEC3-1|A0A8V0YEC3_CHICK Isoform 1 of NIPA like domain containing 2 OS=Gallus gallus OX=9031 GN=NIPAL2 PE=3 SV=1 CANONICAL=A0A8V0YEC3-1" }, "locus": { "chromosome": "2", "start_pos": 127159047, "end_pos": 127131434, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027949.1", "url": "https://www.ensembl.org/id/ENSGALT00010027949.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016041.1", "url": "https://www.ensembl.org/id/ENSGALP00010016041.1" } ] } }, { "isoform_ac": "A0A8V0YJ19-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEC3/entry#A0A8V0YJ19-1", "sequence": { "sequence": "MGILPESEWASWGTFFEGTFSSRWYNKHKTELLGVLLAAASDFLISISLSIQKCSHLRLARQAELQPFYRSKLWWCGAVLLGIGELGNFTAYGFAPIALVAPLGCVSIIGSAFISVIFLKKTMRAADILGGALAVVGTYLLVTFAPNVSQQLTARQVQNDLVSWPFLVYVILEIIIFCILLYFYKRKAVKHIVVLLMMVALLASLTVIAVKAVASMIILSAKGKMQLTYPVFYIMLILMATSCVFQVKFLNQALHLYEARAVVPINFVFCTTSAIISGVIFYQEFQSAAFLSVFMFLFGCLLSFLSVFVIAVNKNEERLQVPYIDCGCIPGQKLTGKIQPDSYGSCYGTLNNKDDSGKSQS", "length": 361, "header": "tr|A0A8V0YJ19-1|A0A8V0YJ19_CHICK Computationally mapped isoform of NIPA like domain containing 2 OS=Gallus gallus OX=9031 GN=NIPAL2 PE=3 SV=1 CANONICAL=A0A8V0YEC3-1" }, "locus": { "chromosome": "2", "start_pos": 127177313, "end_pos": 127131434, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027946.1", "url": "https://www.ensembl.org/id/ENSGALT00010027946.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016039.1", "url": "https://www.ensembl.org/id/ENSGALP00010016039.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:771428", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:771428", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZKE2-1", "protein_name": "NIPA-like domain containing 2", "gene_name": "Nipal2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASPAPTGPQDDASAVLDELSRNFTYWAPGPSNGSLSSAWYHRNQIHLFGVLLAILGNLVISISLNIQKYSHLHLAQKEHPKPYFKSVLWLSGVLLMAIGETGNFAAYGVAPITLIAPLGCVSVTGFLSVALAILELALQNKLVLISKGSTCFCLLSTGNKGSAVISVIFLKENLRASDLLGMTLAFAGTYLLVNFAPNITQAISARTIQYYFVGWQFLVYMILEILVFCILLYFHKRKGKKHIVILLTLVALLASLTVISVKAVSGMITLSVTGKMQLTYAIFYIMLVIMIASCVFQVKFLNQATELYTMTTVVPVNHVFFTTSAIIAGIIFYQEFLGAAFLTVFIYLFGCFLSFLGVFLVTRNREREYLQQSFIDFGNIPGKQMLDKIQPDSNGLSYGSLPDGGDSTRGQRAEKKEA", "length": 419 }, "evidence": [ { "id": "A0A8V0YEC3", "url": "https://omabrowser.org/oma/group/A0A8V0YEC3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E1BHG8-1", "protein_name": "NIPA like domain containing 2", "gene_name": "NIPAL2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAAPAPGEPGAAASAVLDELARNFTYGAQGAGNGSLSGAWYRRNQIHLFGVLLAILGNLVISISLNIQKYSHLRLAQQEHPRPYFRSVLWWGGVILMALGEMGNFVAYGVAPITLIAPLGCMSVTGSAITSVMFLRENLRASDLIGMTLALAGTYLLVNFAPNITQAISARTVQYYFVGWQFMIYMILEILVFCILLYFHKRKGMKHIVILLTLVALLASVTVISVKAVSGMITFSVTDKMQLTYPIFYIMCIIMIASCVFQVKLLNQATKLYNTATVVPVNHIFFTISAIIAGIIFYQEFLGAAFLTIFIYLFGCFLSFLGVVLVTRNREKEHLPQPYIDFGNVPGKQILDKIQPDSSGLSYGTLPDGSDSIKSPNEEKKGV", "length": 383 }, "evidence": [ { "id": "A0A8V0YEC3", "url": "https://omabrowser.org/oma/group/A0A8V0YEC3/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q91WC7-1", "protein_name": "NIPA-like protein 2", "gene_name": "Nipal2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAPARTAPEDDASAVLDELSRNFTYWAPGPGNGSLSSAWYRRNQIHLFGVLLAILGNLVISISLNIQKYSHLHLAQKEHPKPYFKSVLWLSGVLLTALGETGNFAAYGVAPITLIAPLGCMSVTGSAIISVLFLKENLRASDLLGMTLAFAGTYLLVNFAPNITQAISARTVQYYFVGWQFLVYVILEILVFCILLYFHKRKGMKHIVVLLTLVALLASLTVISVKAVSGMITLSVTGKMQLTYAIFYIMLVIMIASCVFQVKFLNQATELYTMTTVVPVNHVFFTTSAIIAGIIFYQEFLGAAFLTVFIYLFGCFLSFLGVFLVTRNREKEHLQQSFVDLGDIPGKQMLDKVQPDSNGLSYGTLPDGGDSTRGQCGEKKES", "length": 383 }, "evidence": [ { "id": "A0A8V0YEC3", "url": "https://omabrowser.org/oma/group/A0A8V0YEC3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9H841-2", "protein_name": "NIPA-like protein 2", "gene_name": "NIPAL2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAVAPAGPGDSASAALDELSLNFTYGAPGAGNGSLSGDWYRRNQIHLFGVLLAILGNLVISISLNIQKYSHLQLAQQEHPRPYFKSVLWWGGVLLMAVGETGNFAAYGFAPITLIAPLGCVSVTGSAIISVTFLKDNLRASDLLGTTLAFAGTYLLVNFAPNITQAISARTVQYYLVGWQFLIYVILEILIFCILLYFYKRKGMKHMVILLTLVAILASLTVISVKAVSGMITFSVMDKMQLTYPIFYIMFIIMIASCVFQVKFLNQATKLYNTTTVVPVNHIFFTISAIIAGIIFYQEFLGAPFLTVFIYLFGCFLSFLGVFLVTRNREKEHLQQSYIDFGNIPGKQMLDKIQPDSHSLSYGTLPDGSDSTKSQSGEKKEV", "length": 383 }, "evidence": [ { "id": "A0A8V0YEC3", "url": "https://omabrowser.org/oma/group/A0A8V0YEC3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "magnesium ion transport", "id": "GO:0015693", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015693", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YEC3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEC3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YEC3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEC3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "magnesium ion transmembrane transporter activity", "id": "GO:0015095", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015095", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YEC3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEC3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 156, "end_pos": 158, "annotation": "n_glycosylation_sequon" }, { "start_pos": 64, "end_pos": 66, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 156, "end_pos": 158 }, { "start_pos": 64, "end_pos": 66 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YEE2-1", "uniprot_ac": "A0A8V0YEE2", "uniprot_id": "A0A8V0YEE2_CHICK", "mass": { "chemical_mass": 199660.0, "monoisotopic_mass": 199660.0 }, "refseq": { "ac": "XP_421891", "name": "germinal-center associated nuclear protein isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_421891" }, "gene_names": [ { "name": "MCM3AP", "type": "recommended", "evidence": [ { "id": "A0A8V0YEE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEE2" } ] }, { "name": "MCM3AP", "type": "synonym", "evidence": [ { "id": "XP_421891", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_421891" } ] } ], "protein_names": [ { "name": "Germinal-center associated nuclear protein", "type": "recommended", "evidence": [ { "id": "A0A8V0YEE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEE2/entry#names_and_taxonomy" } ] }, { "name": "2.3.1.48", "type": "synonym", "evidence": [ { "id": "A0A8V0YEE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEE2/entry#names_and_taxonomy" } ] }, { "name": "germinal-center associated nuclear protein isoform X1", "type": "synonym", "evidence": [ { "id": "XP_421891", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_421891" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052538.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jan 4, 2016 this sequence version replaced XP_421891.3. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_421891", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_421891" } ] }, { "annotation": "As a component of the TREX-2 complex, involved in the export of mRNAs to the cytoplasm through the nuclear pores. Through the acetylation of histones, affects the assembly of nucleosomes at immunoglobulin variable region genes and promotes the recruitment and positioning of transcription complex to favor DNA cytosine deaminase AICDA/AID targeting, hence promoting somatic hypermutations.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YEE2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEE2#function" }, { "database": "UniProtKB", "id": "ARBA00055631", "url": "https://www.uniprot.org/uniprotkb/ARBA00055631#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YEE2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEE2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MCM3AP", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEE2", "locus": { "chromosome": "7", "start_pos": 6885150, "end_pos": 6913775, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010010646", "url": "https://www.ensembl.org/id/ENSGALG00010010646" } ] } } ], "crossref": [ { "id": "424036", "url": "https://www.ncbi.nlm.nih.gov/gene/424036", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000717", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000717", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005062", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005062", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012677", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012677", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR031907", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031907", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR031910", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031910", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045107", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045107", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:424036", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424036", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DMTIFWH", "url": "https://omabrowser.org/oma/group/DMTIFWH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YEE2", "url": "https://www.orthodb.org/?gene=A0A8V0YEE2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12436", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12436", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12436:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12436:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03399", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03399", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16766", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16766", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16769", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16769", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_421891", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_421891", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "21992", "url": "https://www.rhea-db.org/rhea/21992", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YEE2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEE2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YEE2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEE2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNAGGPFRGPPAFPPPLRFGQTAAPHFVPAPPYGLGQAVGNAGFSFKPPTNLGGLPAPGDAAGGAFAPPEFRFKAPDGPAAFTFSPPFGFAPEAAGSEPPAPGGGFSFSRPAPPLGRPEEGAARPPSNAGEEAGEAAPKGLKRKEERERSPRRMAAAGGRAAAPPEKRAVLLSRPRGGALFGRTLKEVLRSQGRERGEPERGPGEEPAAEGREGPHPARLGPADGAAVTPARRARGNDSTDSLGGSSPGELTAIQCKNVPDYLNDRTVLEKHFGQFVKVRRVMTRRNKKTAVVHFFDHASAALAKKKAKELHKDIVTFWQKKKTSPAKREFSSKEKTASEDEGRQNSEEQNYQHSPLRKPLIRSSASAVMPGRSSPAKKPGLRKALQFEVDLFDSSSEGQNSEAVGASLSSLSNLVGLVAETSEERYRLLDQRDKIMRQARIKRTDLGKAKTIVGTCPDMCPEKERYMRETRNQLSIFELLLGSDKVNHAAAIKEYSRSSADQEEPLPHELRPSEVLSMTMDYLVTNIMDQGEGNYREWYDFVWNRTRGIRKDITQQHLCNPLMVSLIEKCTRFHIHCAHHLCEEPMSSFDAKINNENMTKCLQSLKEMYQDLANKGIYCKSEAEFRGYNVLLNLNKGDILREVQQFHPEVRNSPEVRFAVQAFAALNSNNFVRFFKLVQAASYLNACLLHCYFNQIRKDALKSLNIAYTVSTQRCTAFPLDHLVHMLLFKDCEEATDFISYYGLSVSDGTYVELNRSAFLEPDGLPKPRKSLFVSQKLTVSVGEVVNGRPLPPVPHHVPVSSFNGQSKYIGGVAAGDQAGSNQQSSMEAAEGRVESKGVDLDVPAVRVQPPAHLLPSLLPRPLMAALPAAQTVSQSAVQPDPLPSKPQPVYTDMDIAEVVNGLVHDVVKGECREVGRAGADYVTAAICTSEATMKELVAEVMEEVLRQVAVTMFNAERERVKEERRRVEEERQRQEREQLIKRLSQLVSMELMEEVINETVQEASANELKCALERDQQARIARCSEEVCGHVMDLFLEDEIFQIAKETIQELQCFCKYLQRWREAVAARTKLKHQMKAFPAAPCCMDPKNKLKALSPSAEWPITMENLCKRIVNMGNGGKLGVSCTRLNWLRNKTAHEIKVQHFYQQLLSDLAWTPLDLASLIAEHIPVQQEHVFWKVLLVLPNDDEYAEDDPNRILIEWLKAKFMKDKSWKKTASCAEIRIQTLTLFNSSGVQGSRNIKVSVCVKVVHGVLSDSELDASNTQKDLLGTSGLILLLPPRVRSEDVAEEDVYWLSALLQLKQLLQVKPFQPIVPLLVLVPSQEEEATEKEVEEGLMLQDLISAQLISDYMIVELAGSINDLEGTRKISAAVSWLVSKCPNSLELCSQTLQEYIEDGIDGEFGKRFYHDWRERRLAGLPSQEPGVIIELYNSVLQFLSEVASSEHLCDLSWPVTEFSEPGGNKLLPHLHWNVPDHLAWLKKAVLSFQIPYLDLPPLGAPWRPVCRMIFQYASQIASSSHTQPLIQSQVENLLSKTYQKWKNGPLGNSGDGPSVDEIPWDDILATCIDHKLRDWKPPKLPVAPEAVSEDGQIRVYFFKEHLKNFTLPFSWEQARLRTQEEIRQDHKRSRVKSPVSFKKPCRVFMTDQYGAGANILSGQGRNISSADELTASAQDLPERLLTQLQLEKMESRRFEEQLHQYLAEDTEPLGDLVGFPLYLPQSLISTPTLAGPLIKSPMSSVQVDGSEARLELSMDDRSPALSDRLRHLQRLLRANKEGEVASELHLSALMDMVDI", "length": 1792, "header": "tr|A0A8V0YEE2-1|A0A8V0YEE2_CHICK Isoform 1 of Germinal-center associated nuclear protein OS=Gallus gallus OX=9031 GN=MCM3AP PE=1 SV=1 CANONICAL=A0A8V0YEE2-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YEE2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEE2/entry#A0A8V0YEE2-1", "sequence": { "sequence": "MNAGGPFRGPPAFPPPLRFGQTAAPHFVPAPPYGLGQAVGNAGFSFKPPTNLGGLPAPGDAAGGAFAPPEFRFKAPDGPAAFTFSPPFGFAPEAAGSEPPAPGGGFSFSRPAPPLGRPEEGAARPPSNAGEEAGEAAPKGLKRKEERERSPRRMAAAGGRAAAPPEKRAVLLSRPRGGALFGRTLKEVLRSQGRERGEPERGPGEEPAAEGREGPHPARLGPADGAAVTPARRARGNDSTDSLGGSSPGELTAIQCKNVPDYLNDRTVLEKHFGQFVKVRRVMTRRNKKTAVVHFFDHASAALAKKKAKELHKDIVTFWQKKKTSPAKREFSSKEKTASEDEGRQNSEEQNYQHSPLRKPLIRSSASAVMPGRSSPAKKPGLRKALQFEVDLFDSSSEGQNSEAVGASLSSLSNLVGLVAETSEERYRLLDQRDKIMRQARIKRTDLGKAKTIVGTCPDMCPEKERYMRETRNQLSIFELLLGSDKVNHAAAIKEYSRSSADQEEPLPHELRPSEVLSMTMDYLVTNIMDQGEGNYREWYDFVWNRTRGIRKDITQQHLCNPLMVSLIEKCTRFHIHCAHHLCEEPMSSFDAKINNENMTKCLQSLKEMYQDLANKGIYCKSEAEFRGYNVLLNLNKGDILREVQQFHPEVRNSPEVRFAVQAFAALNSNNFVRFFKLVQAASYLNACLLHCYFNQIRKDALKSLNIAYTVSTQRCTAFPLDHLVHMLLFKDCEEATDFISYYGLSVSDGTYVELNRSAFLEPDGLPKPRKSLFVSQKLTVSVGEVVNGRPLPPVPHHVPVSSFNGQSKYIGGVAAGDQAGSNQQSSMEAAEGRVESKGVDLDVPAVRVQPPAHLLPSLLPRPLMAALPAAQTVSQSAVQPDPLPSKPQPVYTDMDIAEVVNGLVHDVVKGECREVGRAGADYVTAAICTSEATMKELVAEVMEEVLRQVAVTMFNAERERVKEERRRVEEERQRQEREQLIKRLSQLVSMELMEEVINETVQEASANELKCALERDQQARIARCSEEVCGHVMDLFLEDEIFQIAKETIQELQCFCKYLQRWREAVAARTKLKHQMKAFPAAPCCMDPKNKLKALSPSAEWPITMENLCKRIVNMGNGGKLGVSCTRLNWLRNKTAHEIKVQHFYQQLLSDLAWTPLDLASLIAEHIPVQQEHVFWKVLLVLPNDDEYAEDDPNRILIEWLKAKFMKDKSWKKTASCAEIRIQTLTLFNSSGVQGSRNIKVSVCVKVVHGVLSDSELDASNTQKDLLGTSGLILLLPPRVRSEDVAEEDVYWLSALLQLKQLLQVKPFQPIVPLLVLVPSQEEEATEKEVEEGLMLQDLISAQLISDYMIVELAGSINDLEGTRKISAAVSWLVSKCPNSLELCSQTLQEYIEDGIDGEFGKRFYHDWRERRLAGLPSQEPGVIIELYNSVLQFLSEVASSEHLCDLSWPVTEFSEPGGNKLLPHLHWNVPDHLAWLKKAVLSFQIPYLDLPPLGAPWRPVCRMIFQYASQIASSSHTQPLIQSQVENLLSKTYQKWKNGPLGNSGDGPSVDEIPWDDILATCIDHKLRDWKPPKLPVAPEAVSEDGQIRVYFFKEHLKNFTLPFSWEQARLRTQEEIRQDHKRSRVKSPVSFKKPCRVFMTDQYGAGANILSGQGRNISSADELTASAQDLPERLLTQLQLEKMESRRFEEQLHQYLAEDTEPLGDLVGFPLYLPQSLISTPTLAGPLIKSPMSSVQVDGSEARLELSMDDRSPALSDRLRHLQRLLRANKEGEVASELHLSALMDMVDI", "length": 1792, "header": "tr|A0A8V0YEE2-1|A0A8V0YEE2_CHICK Isoform 1 of Germinal-center associated nuclear protein OS=Gallus gallus OX=9031 GN=MCM3AP PE=1 SV=1 CANONICAL=A0A8V0YEE2-1" }, "locus": { "chromosome": "7", "start_pos": 6913576, "end_pos": 6886712, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010025335.1", "url": "https://www.ensembl.org/id/ENSGALT00010025335.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010014341.1", "url": "https://www.ensembl.org/id/ENSGALP00010014341.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 229, "start_aa": "Thr", "end_pos": 229, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr229", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:424036", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424036", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2JV99-1", "protein_name": "Germinal-center associated nuclear protein", "gene_name": "Mcm3ap", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MNPVNPFSGQQPGAFAVSSSATGTFQTKSPFRFGQPSLFGQNNQASKSLGFSQVPSFATPSGGSHSSSLPAFGLTQTSSVGLFSGLESTPSFAATSGPSSSSVPGNTAFSFKSASSVGVFSSGPTFGPETGDVAGSGFRKTEFKFKPLENAVFKPILGAESEPEKTQSQIASGFFTFSHPVSSGSGGLTPFSFPQVTNSSATSSSFIFSKPVTSNTSAFAPALSNQNIEEEKRGPKSVFGGLNSSFSTFPMASPGSLGEPFPTNKTSIRQGGEEAISQVESHPALMKGLKRKEDQDRSPRRHCHEAAEDSDPLSRGDHPPDKRPVRLNRPRGGTLFGRTIQEVFKSNKEAGRLGSKESKKDSGFVESGESDHVAIPGGSQSTLVTSRLPAVNKEEETEGRDEKEDSLRGTSVRQSKRSESTDSLGGMSSLELTAIQCKNIPDYLNDRAILEKHFSKIAKVQRVFTRRSKKLAVIHFFDHASAALARKKGKGLHKDMAIFWHKKKISPSKKPFSLKEKQLGEGEASQGIEDSPFQHSPLGKPIVRPATGSLLNKSSPVKKPGLLKIHQFEADPFDSGSEGSEGLGSCVSSLSTLIGTVADTSEEKYRLLDQRDRIMRQARVKRTDLDKARAFVGTCPDMCPEKERYLRETRSQLSVFEVVPGTDQVDHAAAVKEYSRSSADQEEPLPHELRPSAVLSRTMDYLVTQIMDQKEGSLRDWYDFVWNRTRGIRKDITQQHLCDPLTVSLIEKCTRFHIHCAHFMCEEPMSSFDAKINNENMTKCLQSLKEMYQDLRNKGVFCASEAEFQGYNVLLNLNKGDILREVQQFHPDVRNSPEVDFAVQAFAALNSNNFVRFFKLVQSASYLNACLLHCYFNQIRKDALRALNVAYTVSTQRSTVFPLDGVVRMLLFRDCEEATSFLNYHGLTVADGCVELNRSAFLEPEGLYKARKSVFIGRKLTVSVGEVVNGGPLPPVPRHTPVCSFNSQNKYVGESLATELPISAQRSGGDSAGGGRGEEVEAEVDVPPLAVLPQLPPAPSATPVPHVQPLTQAVTPSLFQASTQPEVLLPKPVPVYSDSDLVQVVDELIQEALQVDCEEVSSAGAAYVAAALGVSNAAVEDLITAATTGILRHVAAEEVSMERQRVEEEKRRAEEERLKQERELMLTQLSKGLAAELTELTVTECVWETCSQELKSAVETDQKVRVARCCEAVCTHLVDLFLAEEIFQTAKETLQELQCFCKYLQRWRGAVAARKKLRRQMRAFPAAPCCVDVNDRLQALVPSAECPITEENLAKGLLDLGHAGKVGISCTRLRRLRNKTAHQMKVQHFHQQLLSNAAWAPLDLPSFVAEHLPVKQKRIFWKLVLVLPDGEEQTPESPGRILENWLKVKFTGDGSLVDDTRDNAGDIQTLSVFNTLSSKGDQTVSVNVCIKVARGTLSDSALDAVETRKDLLGASGLMLLLPPKVKSEDVAEEDLYWLSALLQLKQLLQAKPFQPALPLVVLVPSSRGDSTGKGVEDGLMLQDLISAKLISDYIVVEIPDFVNDLHGTVKVSGAVQWLISRCPQALDLCCQTLIQYVEDGISREFSGRFFHDRRERRLGSLASQEPSAIIELFNSVLQFLASVVSSEQLGDISWPVTEFAEVGGSQLLPHLHWNSPEHLAWLKQAVLGFQLPQMDLPPPAALWLPVCSMVIQYTSQIPSSCRTQPVLRSQVESLLCRTYQKWKSKSLCPGQQSGPSVAEIPWDDIITLCINHKLRDWTPPRLPVTLDALSEDGQICVYFFKNRLRKYTVPLSWEQARMQTQRELQLSQGCSGIKSFHPTSSFPTPLLHGRHKGKKKEDGGREGSLSTEDLLRGASAEELLAQCLNNSLLEEREENKRFEDQLQQWLSRDSQAFTESARLPLYLPQTLVSYPDAIKTQTKVKTSTSPQNAGTGDHVRFSEASDTSLTEKLKHLERLIQSSRAEEAASELHLSALLDMVDI", "length": 1975 }, "evidence": [ { "id": "A0A8V0YEE2", "url": "https://omabrowser.org/oma/group/A0A8V0YEE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3H8X9-1", "protein_name": "Germinal-center associated nuclear protein", "gene_name": "Mcm3ap", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MNPVNPFSGQQPGAFAVSSSTTGTYQTKSSFRFGQPPLFGQNNTLGKSLGFSQVSSFATPSVVSHSSSLPTFGVTQTSSVGLFATLESTPSFAATSGPSSSSVPGNTGFSFKSPSSVGVFPSGSTFGPETGEVASSGFRKTEFKFKPMENAVFRPILGAESEPEKTQSQIASGFFTFPHPVSSGSGSLTPFSFSQVTNSSVTSSNFVFSKPANSNTTSVLTPALSNQNVEEEKRGPKSVFGSSNSSFTTFPMPSSASLGEPFSGNKTVIRQGCEEAISLVEPLPTPMKGLKRKEDQERSPRRHCHEAAEDSDPLSRGDHPPDKRPVRLNRPRGGTLFGRTIQDVFKSNKEVSRLSSKESKKESGFVESGESDHVAIPGGSQSTLVPSRLPAVNKEEETEGRDEKEDSLRGTSARQSKRSESTDSLGGLSLLESTAIQCKNIPDYLNDRAVLEKHFSKIAKVQRVFTRRSKKLAVVQFFDHASAALARKKGKGLHKDMVIFWHKKKISPSKKPFSLKEKKLGDGEASQGIEEPPFQHSPLGKPIVRPATGSLMNKSSPVKKPSLLKIHQFEADPFDSGSEGPEGLGSCVSSLSTLIGTVAETSEEKYRLLDQRDRIMRQARVKRTDLDKARAFVGTCPDMCPEKERYLRETRSQLSVFEVVPGTDQVDHAAAVKEYSRSSADQEEPLPHELRPSAVLSRTMDYLVTQIMDQKESSLRDWYDFVWNRTRGIRKDITQQHLCDPLTVSLIEKCTRFHIHCAHFMCEEPMSSFDAKINNENMTKCLQSLKEMYQDLRNKGVFCASEAEFQGYNVLLNLNKGDILREVQQFHSDVRNSPEVNFAVQAFAALNSNNFVRFFKLVQSASYLNACLLHCYFNQIRKDALRALNVAYTVSTQRSTVFPLDGVVRMLLFKDCEEATNFLNYHGLTVADGCVELNRSAFLEPEGLSKARKSVFIARKLTVSVGEVVNGGPLPSVPRHTPVCSFNSQNKYVGESLATELPIGTQRSSADAAGGGRGEEHEAEVGVPPLALLPQPPPAPSATSVIQVTPLASAVAPGLFQSSMQSELLPPKPAPVYSDSDLVQVVDELIQEALQVDCEEVSTAGAAYVAAALGVSNAAVEDLITAATTGILRHVAAEEVSRERQRREEEKRRAEEERLKQERELVLTQLSEGLAAELTELMVTECVWETCSQELKSAVEADQKARIARSCEAVCTHLVDLFLAEEIFQTAKETLQELQCFCKYLQRWREAVAARKKLRRQMRAFPAAPCCVDMNDRLQALVPSAECPIAEENLAKGLLDLGHAGKVGISCTRLRQLRHKTAHQMKVQHFHQQLLSNAAWAPLDLPSFVAEHLPGKHERVFWKLVLVLPDGEEQTPESPGRILENWLKVKFTGDDSLVDITRDNASDIQTLTVYNALSSKGDQTVSVNVCIKVAHGTLSDSALDAVETRKDLLGASGLMLLLPPKVKTEDIAEEDLYWLSALLQLKQLLQAKPFQPALPLVVLVPSSKGDSMGKEVEDGLMLQDLVSAKLISDYIVVEIPDSVNDLQGTMKVSGAVQWLVSRCPQTLDLCCQTLIQYVEDGISREFSGRFFPDRRERRLGGLASQEPGAIIELFNSVLQFLASVVSSEQLCDISWPVMEFAEAGGSQLLPHLHWNSPEHLAWLKQAVLGFQLPQMDLPPAGAPWLPVCSMVIQYTSQIPSSCQTQPVLQSQVENLLCRTYQKWKSKNLSPGQESGPSVAEIPWDDIITLCINHKLSDWTPPRLPITAEALSEDGQICVYFYKNCLRKYDVPLSWEQARKQTQRELQLSHRRSGTKSFHPSTSSFPTPLLHVHHKRKKNEESGREGSLRTEDLMRGASAEELLAQCLSSSLLEEKEENKRFEDQLQQWLSQDSQAFTESTRLPLYLPQTLISFPDTIQTQTVVRASTTRRPQSAEAGEQLQFSEILDTSLTERLKHLERLIRSSREEEVVSELHLSALLDMVDI", "length": 1979 }, "evidence": [ { "id": "A0A8V0YEE2", "url": "https://omabrowser.org/oma/group/A0A8V0YEE2/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "O60318-1", "protein_name": "Germinal-center associated nuclear protein", "gene_name": "MCM3AP", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNPTNPFSGQQPSAFSASSSNVGTLPSKPPFRFGQPSLFGQNSTLSGKSSGFSQVSSFPASSGVSHSSSVQTLGFTQTSSVGPFSGLEHTSTFVATSGPSSSSVLGNTGFSFKSPTSVGAFPSTSAFGQEAGEIVNSGFGKTEFSFKPLENAVFKPILGAESEPEKTQSQIASGFFTFSHPISSAPGGLAPFSFPQVTSSSATTSNFTFSKPVSSNNSLSAFTPALSNQNVEEEKRGPKSIFGSSNNSFSSFPVSSAVLGEPFQASKAGVRQGCEEAVSQVEPLPSLMKGLKRKEDQDRSPRRHGHEPAEDSDPLSRGDHPPDKRPVRLNRPRGGTLFGRTIQDVFKSNKEVGRLGNKEAKKETGFVESAESDHMAIPGGNQSVLAPSRIPGVNKEEETESREKKEDSLRGTPARQSNRSESTDSLGGLSPSEVTAIQCKNIPDYLNDRTILENHFGKIAKVQRIFTRRSKKLAVVHFFDHASAALARKKGKSLHKDMAIFWHRKKISPNKKPFSLKEKKPGDGEVSPSTEDAPFQHSPLGKAAGRTGASSLLNKSSPVKKPSLLKAHQFEGDSFDSASEGSEGLGPCVLSLSTLIGTVAETSKEKYRLLDQRDRIMRQARVKRTDLDKARTFVGTCLDMCPEKERYMRETRSQLSVFEVVPGTDQVDHAAAVKEYSRSSADQEEPLPHELRPLPVLSRTMDYLVTQIMDQKEGSLRDWYDFVWNRTRGIRKDITQQHLCDPLTVSLIEKCTRFHIHCAHFMCEEPMSSFDAKINNENMTKCLQSLKEMYQDLRNKGVFCASEAEFQGYNVLLSLNKGDILREVQQFHPAVRNSSEVKFAVQAFAALNSNNFVRFFKLVQSASYLNACLLHCYFSQIRKDALRALNFAYTVSTQRSTIFPLDGVVRMLLFRDCEEATDFLTCHGLTVSDGCVELNRSAFLEPEGLSKTRKSVFITRKLTVSVGEIVNGGPLPPVPRHTPVCSFNSQNKYIGESLAAELPVSTQRPGSDTVGGGRGEECGVEPDAPLSSLPQSLPAPAPSPVPLPPVLALTPSVAPSLFQLSVQPEPPPPEPVPMYSDEDLAQVVDELIQEALQRDCEEVGSAGAAYAAAALGVSNAAMEDLLTAATTGILRHIAAEEVSKERERREQERQRAEEERLKQERELVLSELSQGLAVELMERVMMEFVRETCSQELKNAVETDQRVRVARCCEDVCAHLVDLFLVEEIFQTAKETLQELQCFCKYLQRWREAVTARKKLRRQMRAFPAAPCCVDVSDRLRALAPSAECPIAEENLARGLLDLGHAGRLGISCTRLRRLRNKTAHQMKVQHFYQQLLSDVAWASLDLPSLVAEHLPGRQEHVFWKLVLVLPDVEEQSPESCGRILANWLKVKFMGDEGSVDDTSSDAGGIQTLSLFNSLSSKGDQMISVNVCIKVAHGALSDGAIDAVETQKDLLGASGLMLLLPPKMKSEDMAEEDVYWLSALLQLKQLLQAKPFQPALPLVVLVPSPGGDAVEKEVEDGLMLQDLVSAKLISDYTVTEIPDTINDLQGSTKVLQAVQWLVSHCPHSLDLCCQTLIQYVEDGIGHEFSGRFFHDRRERRLGGLASQEPGAIIELFNSVLQFLASVVSSEQLCDLSWPVTEFAEAGGSRLLPHLHWNAPEHLAWLKQAVLGFQLPQMDLPPLGAPWLPVCSMVVQYASQIPSSRQTQPVLQSQVENLLHRTYCRWKSKSPSPVHGAGPSVMEIPWDDLIALCINHKLRDWTPPRLPVTSEALSEDGQICVYFFKNDLKKYDVPLSWEQARLQTQKELQLREGRLAIKPFHPSANNFPIPLLHMHRNWKRSTECAQEGRIPSTEDLMRGASAEELLAQCLSSSLLLEKEENKRFEDQLQQWLSEDSGAFTDLTSLPLYLPQTLVSLSHTIEPVMKTSVTTSPQSDMMREQLQLSEATGTCLGERLKHLERLIRSSREEEVASELHLSALLDMVDI", "length": 1980 }, "evidence": [ { "id": "A0A8V0YEE2", "url": "https://omabrowser.org/oma/group/A0A8V0YEE2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9WUU9-1", "protein_name": "Germinal-center associated nuclear protein", "gene_name": "Mcm3ap", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MHPVNPFGGQQPSAFAVSSSTTGTYQTKSPFRFGQPSLFGQNSTPSKSLAFSQVPSFATPSGGSHSSSLPAFGLTQTSSVGLFSSLESTPSFAATSSSSVPGNTAFSFKSTSSVGVFPSGATFGPETGEVAGSGFRKTEFKFKPLENAVFKPIPGPESEPEKTQSQISSGFFTFSHPVGSGSGGLTPFSFPQVTNSSVTSSSFIFSKPVTSNTPAFASPLSNQNVEEEKRVSTSAFGSSNSSFSTFPTASPGSLGEPFPANKPSLRQGCEEAISQVEPLPTLMKGLKRKEDQDRSPRRHCHEAAEDPDPLSRGDHPPDKRPVRLNRPRGGTLFGRTIQEVFKSNKEAGRLGSKESKESGFAEPGESDHAAVPGGSQSTMVPSRLPAVTKEEEESRDEKEDSLRGKSVRQSKRREEWIYSLGGVSSLELTAIQCKNIPDYLNDRAILEKHFSKIAKVQRVFTRRSKKLAVIHFFDHASAALARKKGKGLHKDVVIFWHKKKISPSKKLFPLKEKLGESEASQGIEDSPFQHSPLSKPIVRPAAGSLLSKSSPVKKPSLLKMHQFEADPFDSGSEGSEGLGSCVSSLSTLIGTVADTSEEKYRLLDQRDRIMRQARVKRTDLDKARAFVGTCPDMCPEKERYLRETRSQLSVFEVVPGTDQVDHAAAVKEYSRSSADQEEPLPHELRPSAVLSRTMDYLVTQIMDQKEGSLRDWYDFVWNRTRGIRKDITQQHLCDPLTVSLIEKCTRFHIHCAHFMCEEPMSSFDAKINNENMTKCLQSLKEMYQDLRNKGVFCASEAEFQGYNVLLNLNKGDILREVQQFHPDVRNSPEVNFAVQAFAALNSNNFVRFFKLVQSASYLNACLLHCYFNQIRKDALRALNVAYTVSTQRSTVFPLDGVVRMLLFRDSEEATNFLNYHGLTVADGCVELNRSAFLEPEGLCKARKSVFIGRKLTVSVGEVVNGGPLPPVPRHTPVCSFNSQNKYVGESLATELPISTQRAGGDPAGGGRGEDCEAEVDVPTLAVLPQPPPASSATPALHVQPLAPAAAPSLLQASTQPEVLLPKPAPVYSDSDLVQVVDELIQEALQVDCEEVSSAGAAYVAAALGVSNAAVEDLITAATTGILRHVAAEEVSMERQRLEEEKQRAEEERLKQERELMLTQLSEGLAAELTELTVTECVWETCSQELQSAVEIDQKVRVARCCEAVCAHLVDLFLAEEIFQTAKETLQELQCFCKYLQRWREAVAARKKFRRQMRAFPAAPCCVDVNDRLQALVPSAECPITEENLAKGLLDLGHAGKVGVSCTRLRRLRNKTAHQIKVQHFHQQLLRNAAWAPLDLPSIVSEHLPMKQKRRFWKLVLVLPDVEEQTPESPGRILENWLKVKFTGDDSMVGDIGDNAGDIQTLSVFNTLSSKGDQTVSVNVCIKVAHGTLSDSALDAVETQKDLLGTSGLMLLLPPKVKSEEVAEEELSWLSALLQLKQLLQAKPFQPALPLVVLVPSSRGDSAGRAVEDGLMLQDLVSAKLISDYIVVEIPDSVNDLQGTVKVSGAVQWLISRCPQALDLCCQTLVQYVEDGISREFSRRFFHDRRERRLASLPSQEPSTIIELFNSVLQFLASVVSSEQLCDISWPVMEFAEVGGSQLLPHLHWNSPEHLAWLKQAVLGFQLPQMDLPPPGAPWLPVCSMVIQYTSQIPSSSQTQPVLQSQVENLLCRTYQKWKNKSLSPGQELGPSVAEIPWDDIITLCINHKLRDWTPPRLPVTLEALSEDGQICVYFFKNLLRKYHVPLSWEQARMQTQRELQLSHGRSGMRSIHPPTSTFPTPLLHVHQKGKKKEESGREGSLSTEDLLRGASAEELLAQSLSSSLLEEKEENKRFEDQLQQWLSQDSQAFTESTRLPLYLPQTLVSFPDSIKTQTMVKTSTSPQNSGTGKQLRFSEASGSSLTEKLKLLERLIQSSRAEEAASELHLSALLEMVDM", "length": 1971 }, "evidence": [ { "id": "A0A8V0YEE2", "url": "https://omabrowser.org/oma/group/A0A8V0YEE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "poly(A)+ mRNA export from nucleus", "id": "GO:0016973", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016973", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YEE2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEE2" } ], "pmid": "" }, { "name": "nucleosome organization", "id": "GO:0034728", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034728", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YEE2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEE2" } ], "pmid": "" }, { "name": "mRNA export from nucleus", "id": "GO:0006406", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006406", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YEE2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEE2" } ], "pmid": "" }, { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YEE2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEE2" } ], "pmid": "" }, { "name": "somatic hypermutation of immunoglobulin genes", "id": "GO:0016446", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016446", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YEE2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEE2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 8, "go_terms": [ { "name": "nuclear pore nuclear basket", "id": "GO:0044615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044615", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YEE2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEE2" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YEE2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEE2" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YEE2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEE2" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YEE2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEE2" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YEE2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEE2" } ], "pmid": "" }, { "name": "nuclear membrane", "id": "GO:0031965", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031965", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YEE2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEE2" } ], "pmid": "" }, { "name": "chromosome", "id": "GO:0005694", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005694", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YEE2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEE2" } ], "pmid": "" }, { "name": "transcription export complex 2", "id": "GO:0070390", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070390", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YEE2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEE2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YEE2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEE2" } ], "pmid": "" }, { "name": "nucleic acid binding", "id": "GO:0003676", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003676", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YEE2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEE2" } ], "pmid": "" }, { "name": "histone binding", "id": "GO:0042393", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042393", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YEE2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEE2" } ], "pmid": "" }, { "name": "histone H3 acetyltransferase activity", "id": "GO:0010484", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010484", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YEE2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEE2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1134, "end_pos": 1136, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1230, "end_pos": 1232, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1601, "end_pos": 1603, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1659, "end_pos": 1661, "annotation": "n_glycosylation_sequon" }, { "start_pos": 237, "end_pos": 239, "annotation": "n_glycosylation_sequon" }, { "start_pos": 545, "end_pos": 547, "annotation": "n_glycosylation_sequon" }, { "start_pos": 598, "end_pos": 600, "annotation": "n_glycosylation_sequon" }, { "start_pos": 756, "end_pos": 758, "annotation": "n_glycosylation_sequon" }, { "start_pos": 999, "end_pos": 1001, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "21992", "name": "", "equation": "L-lysyl-[histone] + acetyl-CoA = N(6)-acetyl-L-lysyl-[histone] + CoA + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0X6X9-1", "A0A8V0ZTT2-1", "A0A8V0X885-1", "A0A8V0YEE2-1", "A0A8V0X4X8-1" ], "evidence": [ { "id": "21992", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/21992" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A8V0X4X8", "gene_name": "", "activity": [ { "ec_number": "2.3.1.48", "activity": "L-lysyl-[histone] + acetyl-CoA = N(6)-acetyl-L-lysyl-[histone] + CoA + H(+).", "evidence": [ { "id": "A0A8V0X4X8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X4X8" } ] }, { "ec_number": "2.3.1.48", "activity": "", "evidence": [ { "id": "A0A8V0X4X8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X4X8" } ] } ] }, { "uniprot_ac": "A0A8V0X6X9", "gene_name": "KAT2B", "activity": [ { "ec_number": "2.3.1.48", "activity": "L-lysyl-[histone] + acetyl-CoA = N(6)-acetyl-L-lysyl-[histone] + CoA + H(+).", "evidence": [ { "id": "A0A8V0X6X9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X6X9" } ] }, { "ec_number": "2.3.1.48", "activity": "", "evidence": [ { "id": "A0A8V0X6X9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X6X9" } ] } ] }, { "uniprot_ac": "A0A8V0X885", "gene_name": "", "activity": [ { "ec_number": "2.3.1.48", "activity": "L-lysyl-[histone] + acetyl-CoA = N(6)-acetyl-L-lysyl-[histone] + CoA + H(+).", "evidence": [ { "id": "A0A8V0X885", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X885" } ] }, { "ec_number": "2.3.1.48", "activity": "", "evidence": [ { "id": "A0A8V0X885", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X885" } ] } ] }, { "uniprot_ac": "A0A8V0YEE2", "gene_name": "MCM3AP", "activity": [ { "ec_number": "2.3.1.48", "activity": "L-lysyl-[histone] + acetyl-CoA = N(6)-acetyl-L-lysyl-[histone] + CoA + H(+).", "evidence": [ { "id": "A0A8V0YEE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEE2" } ] }, { "ec_number": "2.3.1.48", "activity": "", "evidence": [ { "id": "A0A8V0YEE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEE2" } ] } ] }, { "uniprot_ac": "A0A8V0ZTT2", "gene_name": "KAT2A", "activity": [ { "ec_number": "2.3.1.48", "activity": "L-lysyl-[histone] + acetyl-CoA = N(6)-acetyl-L-lysyl-[histone] + CoA + H(+).", "evidence": [ { "id": "A0A8V0ZTT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTT2" } ] }, { "ec_number": "2.3.1.48", "activity": "", "evidence": [ { "id": "A0A8V0ZTT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTT2" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YEE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEE2" }, { "id": "PS50250", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50250" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PCI", "eco_id": "ECO_0000259", "start_pos": 595, "end_pos": 779, "start_aa": "Asn", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.3.1.48", "ec_name": "L-lysyl-[histone] + acetyl-CoA = N(6)-acetyl-L-lysyl-[histone] + CoA + H(+).", "evidence": [ { "id": "2.3.1.48", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.48" }, { "id": "2.3.1.48", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.3.1.48" } ] } ], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 229 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1134, "end_pos": 1136 }, { "start_pos": 1230, "end_pos": 1232 }, { "start_pos": 1601, "end_pos": 1603 }, { "start_pos": 1659, "end_pos": 1661 }, { "start_pos": 237, "end_pos": 239 }, { "start_pos": 545, "end_pos": 547 }, { "start_pos": 598, "end_pos": 600 }, { "start_pos": 756, "end_pos": 758 }, { "start_pos": 999, "end_pos": 1001 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { 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"snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YEF4-1", "uniprot_ac": "A0A8V0YEF4", "uniprot_id": "A0A8V0YEF4_CHICK", "mass": { "chemical_mass": 132332.0, "monoisotopic_mass": 132332.0 }, "refseq": { "ac": "XP_004938561", "name": "TBC1 domain family member 8 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004938561" }, "gene_names": [ { "name": "TBC1D8", "type": "recommended", "evidence": [ { "id": "A0A8V0YEF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEF4" } ] }, { "name": "TBC1D8", "type": "synonym", "evidence": [ { "id": "XP_004938561", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004938561" } ] } ], "protein_names": [ { "name": "TBC1 domain family member 8", "type": "recommended", "evidence": [ { "id": "A0A8V0YEF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEF4/entry#names_and_taxonomy" } ] }, { "name": "TBC1 domain family member 8 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_004938561", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004938561" } ] }, { "name": "Vascular Rab-GAP/TBC-containing protein", "type": "synonym", "evidence": [ { "id": "A0A8V0YEF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEF4/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004938561", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004938561" } ] }, { "annotation": "May act as a GTPase-activating protein for Rab family protein(s).", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YEF4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEF4#function" }, { "database": "UniProtKB", "id": "ARBA00043879", "url": "https://www.uniprot.org/uniprotkb/ARBA00043879#function" }, { "database": "UniProtKB", "id": "A0A8V0YKT8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKT8#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YEF4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEF4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TBC1D8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEF4", "locus": { "chromosome": "1", "start_pos": 133481605, "end_pos": 133531623, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013480", "url": "https://www.ensembl.org/id/ENSGALG00010013480" } ] } } ], "crossref": [ { "id": "A0A8V0YEF4", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YEF4", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd13349", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13349", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd13353", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13353", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "428012", "url": "https://www.ncbi.nlm.nih.gov/gene/428012", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000195", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000195", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004182", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004182", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011992", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011992", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035969", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035969", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036009", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036009", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036016", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036016", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:428012", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:428012", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "GSEVYWA", "url": "https://omabrowser.org/oma/group/GSEVYWA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YEF4", "url": "https://www.orthodb.org/?gene=A0A8V0YEF4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YKT8", "url": "https://www.orthodb.org/?gene=A0A8V0YKT8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47666", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47666", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47666:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47666:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00566", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00566", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02893", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02893", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_004938561", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004938561", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YEF4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEF4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YEF4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEF4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YKT8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKT8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YKT8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKT8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MWLKPEEVLLKNALKLWVTQKSSGYFVLQRRRGHGDGGGRFTGRLVGALDAVLDSNARVAPFRILLQVPGSQVYSAIACGELLNGSEVYWAIAIGATAEEINQHWEWLEQNLLHTLSVFDNKEDIVSFVKGKVKALIAEETSSKLAEQEEDPEKFREALVKFESRFNFPEAEKLITYYSCCCWKGKVPRQGWLYLSINHLCFYSFFLGKELKLIIPWVEVQKLERTSNVFMTDTVRVTTPNKERDFSTFLNIAEAFRIMEQLADVTLRRLLDNEIFELDPGLQDPTQITKRDLEARAQNEFFRAFFRLPRKEKLHEVVDCSLWTPFSRCHTVGRMYTSDSYICFASKENGSCNVIIPLREVISIEKMEDTSLLPNPIIVSIRSKTAFQFIELKERDALVENLLQRLKEVNSSNSVHCNNLQSKNQNTPVFTSTCVLGGCEPGSLGMEAAQSKDGSGCNKESSYLLNAEALRSDFHQSGMAGLDFGKSREQIKESLWDDHFVEYGRTVCMFRTEKIRKLVAMGIPESLRGKLWLLFSDAVTDLASHPGYYVHLVEASMGKCCMVTEEIERDLHRSLPEHPAFQSETGIAALRRVLTAYAHRNPKIGYCQSMNILTSVLLLYAKEEEAFWLLVAVCERMLPDYFNHRVIGAQVDQSVFEELIKEQLPELAEHMKDLTTLASISLSWFLTLFLSIMPLESAVNVVDCFFYDGIKAIFQLGLAILEANAVDLCNSKDDGQALMILSRFLEHVKNEESPLPPIGNHHAFFSDDQEATPVTEIANLIHDSYEKFGDHSVEQIEHMRYKHRIRVLQSHEDTTKQNVLRVVIPDVSILPEDLEELYDLFKREHLIRCYWDTAGPATERHDPSRPYAEQYRIDAQQFTNLYKLVSPWTCGEHTDILAERTFRLLDENMDHLIEFKGLASCLDVMYNGEMNEKIKFLYKLHIPPALTEDERDSQSPLKNPLLSTSRPLVIGKSNGDAVDYQKQLKQMLKDLAKEKDTKTEKELPKMSQREFIQFCKTLYSMFHEDPEENDLYQAIATVTTLLLQIGEVGQRSISLGSGSDEFSEDLQAQASASDHDAVFNDTVKTPHRDSQSSPVTEGDWTVSFEHILASLLTEQSLVNFFEKPLELKPKLENAKLNQYSLKTNGMGCQSRSEHTKLNTQ", "length": 1160, "header": "tr|A0A8V0YEF4-1|A0A8V0YEF4_CHICK Isoform 1 of TBC1 domain family member 8 OS=Gallus gallus OX=9031 GN=TBC1D8 PE=4 SV=1 CANONICAL=A0A8V0YEF4-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YEF4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEF4/entry#A0A8V0YEF4-1", "sequence": { "sequence": "MWLKPEEVLLKNALKLWVTQKSSGYFVLQRRRGHGDGGGRFTGRLVGALDAVLDSNARVAPFRILLQVPGSQVYSAIACGELLNGSEVYWAIAIGATAEEINQHWEWLEQNLLHTLSVFDNKEDIVSFVKGKVKALIAEETSSKLAEQEEDPEKFREALVKFESRFNFPEAEKLITYYSCCCWKGKVPRQGWLYLSINHLCFYSFFLGKELKLIIPWVEVQKLERTSNVFMTDTVRVTTPNKERDFSTFLNIAEAFRIMEQLADVTLRRLLDNEIFELDPGLQDPTQITKRDLEARAQNEFFRAFFRLPRKEKLHEVVDCSLWTPFSRCHTVGRMYTSDSYICFASKENGSCNVIIPLREVISIEKMEDTSLLPNPIIVSIRSKTAFQFIELKERDALVENLLQRLKEVNSSNSVHCNNLQSKNQNTPVFTSTCVLGGCEPGSLGMEAAQSKDGSGCNKESSYLLNAEALRSDFHQSGMAGLDFGKSREQIKESLWDDHFVEYGRTVCMFRTEKIRKLVAMGIPESLRGKLWLLFSDAVTDLASHPGYYVHLVEASMGKCCMVTEEIERDLHRSLPEHPAFQSETGIAALRRVLTAYAHRNPKIGYCQSMNILTSVLLLYAKEEEAFWLLVAVCERMLPDYFNHRVIGAQVDQSVFEELIKEQLPELAEHMKDLTTLASISLSWFLTLFLSIMPLESAVNVVDCFFYDGIKAIFQLGLAILEANAVDLCNSKDDGQALMILSRFLEHVKNEESPLPPIGNHHAFFSDDQEATPVTEIANLIHDSYEKFGDHSVEQIEHMRYKHRIRVLQSHEDTTKQNVLRVVIPDVSILPEDLEELYDLFKREHLIRCYWDTAGPATERHDPSRPYAEQYRIDAQQFTNLYKLVSPWTCGEHTDILAERTFRLLDENMDHLIEFKGLASCLDVMYNGEMNEKIKFLYKLHIPPALTEDERDSQSPLKNPLLSTSRPLVIGKSNGDAVDYQKQLKQMLKDLAKEKDTKTEKELPKMSQREFIQFCKTLYSMFHEDPEENDLYQAIATVTTLLLQIGEVGQRSISLGSGSDEFSEDLQAQASASDHDAVFNDTVKTPHRDSQSSPVTEGDWTVSFEHILASLLTEQSLVNFFEKPLELKPKLENAKLNQYSLKTNGMGCQSRSEHTKLNTQ", "length": 1160, "header": "tr|A0A8V0YEF4-1|A0A8V0YEF4_CHICK Isoform 1 of TBC1 domain family member 8 OS=Gallus gallus OX=9031 GN=TBC1D8 PE=4 SV=1 CANONICAL=A0A8V0YEF4-1" }, "locus": { "chromosome": "1", "start_pos": 133531541, "end_pos": 133482113, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032445.1", "url": "https://www.ensembl.org/id/ENSGALT00010032445.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019199.1", "url": "https://www.ensembl.org/id/ENSGALP00010019199.1" } ] } }, { "isoform_ac": "A0A8V0YKT8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEF4/entry#A0A8V0YKT8-1", "sequence": { "sequence": "MWLKPEEVLLKNALKLWVTQKSSGYFVLQRRRGHGDGGGRFTGRFSLLTRAFYPLCKGRLVGALDAVLDSNARVAPFRILLQVPGSQVYSAIACGATAEEINQHWEWLEQNLLHTLSVFDNKEDIVSFVKGKVKALIAEETSSKLAEQEEDPEKFREALVKFESRFNFPEAEKLITYYSCCCWKGKVPRQGWLYLSINHLCFYSFFLGKELKLIIPWVEVQKLERTSNVFMTDTVRVTTPNKERDFSTFLNIAEAFRIMEQLADVTLRRLLDNEIFELDPGLQDPTQITKRDLEARAQNEFFRAFFRLPRKEKLHEVVDCSLWTPFSRCHTVGRMYTSDSYICFASKENGSCNVIIPLREVISIEKMEDTSLLPNPIIVSIRSKTAFQFIELKERDALVENLLQRLKEVNSSNSVHCNNLQSKNQNTPVFTSTCVLGGCEPGSLGMEAAQSKDGSGCNKESSYLLNAEALRSDFHQSGMAGLDFGKSREQIKESLWDDHFVEYGRTVCMFRTEKIRKLVAMGIPESLRGKLWLLFSDAVTDLASHPGYYVHLVEASMGKCCMVTEEIERDLHRSLPEHPAFQSETGIAALRRVLTAYAHRNPKIGYCQSMNILTSVLLLYAKEEEAFWLLVAVCERMLPDYFNHRVIGAQVDQSVFEELIKEQLPELAEHMKDLTTLASISLSWFLTLFLSIMPLESAVNVVDCFFYDGIKAIFQLGLAILEANAVDLCNSKDDGQALMILSRFLEHVKNEESPLPPIGNHHAFFSDDQEATPVTEIANLIHDSYEKFGDHSVEQIEHMRYKHRIRVLQSHEDTTKQNVLRVVIPDVSILPEDLEELYDLFKREHLIRCYWDTAGPATERHDPSRPYAEQYRIDAQQFTNLYKLVSPWTCGEHTDILAERTFRLLDENMDHLIEFKGLASCLDVMYNGEMNEKIKFLYKLHIPPALTEDERDSQSPLKNPLLSTSRPLVIGKSNGDAVDYQKQLKQMLKDLAKEKDTKTEKELPKMSQREFIQFCKTLYSMFHEDPEENDLYQAIATVTTLLLQIGEVGQRSISLGSGSDEFSEDLQAQASASDHDAVFNDTVKTPHRDSQSSPVTEGDWTVSFEHILASLLTEQSLVNFFEKPLELKPKLENAKLNQYSLKTNGMGCQSRSEHTKLNTQ", "length": 1160, "header": "tr|A0A8V0YKT8-1|A0A8V0YKT8_CHICK Computationally mapped isoform of TBC1 domain family member 8 OS=Gallus gallus OX=9031 GN=TBC1D8 PE=4 SV=1 CANONICAL=A0A8V0YEF4-1" }, "locus": { "chromosome": "1", "start_pos": 133531541, "end_pos": 133482113, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032442.1", "url": "https://www.ensembl.org/id/ENSGALT00010032442.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019196.1", "url": "https://www.ensembl.org/id/ENSGALP00010019196.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:428012", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:428012", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "F1LWZ7-1", "protein_name": "TBC1 domain family member 8", "gene_name": "Tbc1d8", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MWLKPEEVLLKNALKLWVTQKSSCYFVLQRRRGHGEGGGRLTGRLVGALDAVLDSSARVAPFRILLQVPGSQVYSPIACGELLNGSDIYWAIATGATLEEINRHWDWLEQNLLHTLSVFDNKDDIASFVKGKVKALIAEETSSRLAEQEEEPEKFREALVKFEARFNFPEAEKLVTYYSCCCWKGRVPRQGWLYLSINHLCFYSFFLGKELKLVIPWVDIQKLERTSNVFLTDTIRITTQNKERDFSTFLNLDEVFKIMEQLADVTLRRLLDNEVFDLDPDLQEPSQITKRDLEARAQNEFFRAFFRLPRKEKLHAVVDCSLWTPFSRCHTAGRIFSSDSYICFASREDGCCHVVLPLREVVSIEKMEDTSLLPNPIIVSIRSKMAFQFIELKDRENLVEGLLLRLKQVHANHPVHYETSPSDDDMASPVFYSTSICTDKFGDLEMVSSQSSEEREKEKSPLPHPEPLTAVFQQSGSQSPDSRLSREQIKISLWNDHFAEYGRTVCMFRTEKIRKLVAMGIPESLRGRLWLLFSDAVTDLASHPGYYGNLVEQSLGRCCLVTEEIERDLHRSLPEHPAFQNETGIAALRRVLTAYAHRNPKIGYCQSMNILTSVLLLYAKEEEAFWLLVAVCERMLPDYFNHRVIGAQVDQSVFEELIKEHLPELAEHMSDLSALASISLSWFLTLFLSIMPLESAVNVVDCFFYDGIKAIFQLGLAVLEANAEELCSSKDDGQALMILSRFLDHIKNEDSPGPPIGSHHAFFSDDQEPCPVTDIADLIRDSYEKFGNQSVEQIEHLRCKHRIRVLQGHEDTTKQNVLRVVIPEVSILPEDLEELYDLFKRAHMMNCYWEHHRPIALRHDPSRPYAEQYRIDACQFAHLFQLVSPWTCGAHTEILAERIFRLLDDNMDQLIEFKAFVSCLDVMYNGEMSEKIKLLYRLHIPPALTENDRDSQSPLKNPLLSTSRPLVLGRPNGDTIDYQKQLKQMIKDLAKEKDKMEKELPKMSQREFIQFCKTLYSMFHEDPEENDLYQAIATVTTLLLQIGEVGQRGSSSGSCSQECEEPQASAPPEQDSVFAEAGKSPQAFPETEGDWTVSLEHILASLLTEQSLVNFFEKPLNIKSKLENAKLNQYSLKAMEMSHPSQPELKLNSL", "length": 1150 }, "evidence": [ { "id": "A0A8V0YEF4", "url": "https://omabrowser.org/oma/group/A0A8V0YEF4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O95759-1", "protein_name": "TBC1 domain family member 8", "gene_name": "TBC1D8", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MWLKPEEVLLKNALKLWVTQKSSCYFILQRRRGHGEGGGRLTGRLVGALDAVLDSNARVAPFRILLQVPGSQVYSPIACGATLEEINQHWDWLEQNLLHTLSVFDNKDDIASFVKGKVKALIAEETSSRLAEQEEEPEKFREALVKFEARFNFPEAEKLVTYYSCCCWKGRVPRQGWLYLSINHLCFYSFFLGKELKLVVPWVDIQKLERTSNVFLTDTIRITTQNKERDFSMFLNLDEVFKVMEQLADVTLRRLLDNEVFDLDPDLQEPSQITKRDLEARAQNEFFRAFFRLPRKEKLHAVVDCSLWTPFSRCHTTGRMFASDSYICFASREDGCCKIILPLREVVSIEKMEDTSLLPHPIIVSIRSKVAFQFIELRDRDSLVEALLARLKQVHANHPVHYDTSADDDMASLVFHSTSMCSDHRFGDLEMMSSQNSEESEKEKSPLMHPDALVTAFQQSGSQSPDSRMSREQIKISLWNDHFVEYGRTVCMFRTEKIRKLVAMGIPESLRGRLWLLFSDAVTDLASHPGYYGNLVEESLGKCCLVTEEIERDLHRSLPEHPAFQNETGIAALRRVLTAYAHRNPKIGYCQSMNILTSVLLLYTKEEEAFWLLVAVCERMLPDYFNHRVIGAQVDQSVFEELIKGHLPELAEHMNDLSALASVSLSWFLTLFLSIMPLESAVNVVDCFFYDGIKAIFQLGLAVLEANAEDLCSSKDDGQALMILSRFLDHIKNEDSPGPPVGSHHAFFSDDQEPYPVTDISDLIRDSYEKFGDQSVEQIEHLRYKHRIRVLQGHEDTTKQNVLRVVIPEVSILPEDLEELYDLFKREHMMSCYWEQPRPMASRHDPSRPYAEQYRIDARQFAHLFQLVSPWTCGAHTEILAERTFRLLDDNMDQLIEFKAFVSCLDIMYNGEMNEKIKLLYRLHIPPALTENDRDSQSPLRNPLLSTSRPLVFGKPNGDAVDYQKQLKQMIKDLAKEKDKTEKELPKMSQREFIQFCKTLYSMFHEDPEENDLYQAIATVTTLLLQIGEVGQRGSSSGSCSQECGEELRASAPSPEDSVFADTGKTPQDSQAFPEAAERDWTVSLEHILASLLTEQSLVNFFEKPLDMKSKLENAKINQYNLKTFEMSHQSQSELKLSNL", "length": 1140 }, "evidence": [ { "id": "A0A8V0YEF4", "url": "https://omabrowser.org/oma/group/A0A8V0YEF4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9Z1A9-1", "protein_name": "TBC1 domain family member 8", "gene_name": "Tbc1d8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWLKPEEVLLKNALKLWVTQKSSCYFVLQRRRGHGEGGGRLTGRLVGALDAVLDSSARVAPFRILLQVPGSQVYSPIACGATLEEINRHWDWLEQNLLHTLSVFDNKDDIASFVKGKVKALIAEETSSRLAEQEEEPEKFREALVKFEARFNFPEAEKLVTYYSCCCWKGRVPRQGWLYLSINHLCFYSFFLGKELKLVIPWVDIQKLERTSNVFLTDTIRITTQNKERDFSTFLNLDEVFKIMEQLADVTLRRLLDNEVFDLDPDLQEPSQITKRDLEARAQNEFFRAFFRLPREEKLHAVADCSLWTPFSRCHTAGRIFSSDSYICFASREDGCCNVVLPLREVVSIEKMEDTSLLPNPIIVSIRSKMAFQFIELKDRENLVEGLLLRLKQVHANHPVHYETSPSDDDMASPVFYSASICTDKFGDLEMVASQSSEEREEKRPLPHPEPLTAVFQQSGSQSPDSRLSREQIKISLWNDHFVEYGRTVCMFRTEKIRKLVAMGIPESLRGRLWLLFSDAVTDLASHPGYYGNLVEQSLGRCCLVTEEIERDLHRSLPEHPAFQNETGIAALRRVLTAYAHRNPKIGYCQSMNILTSVLLLYAKEEEAFWLLVAVCERMLPDYFNHRVIGAQVDQSVFEELIKEQLPELAEHMSDLSALASISLSWFLTLFLSIMPLESAVHVVDCFFYDGIKAIFQLGLAVLEANAEELCSSKDDGQALMVLSRFLDHIKNEDSPGPPIGSHHAFFSDDQEPYPVTDIADLIRDSYEKFGNQSVEQIEHLRCKHRIRVLQGHEDTTKQNVLRVVIPEVSILPEDLEELYDLFKRAHMMSCYWEHHRPMALRHDPSRPYAEQYRIDARQFAHLFQLVSPWTCGVHTEILAERLFRLLDDNMDQLIEFKAFTSCLDIMYNGEMNEKIKLLYRLHIPPALTENDRDSQSPLKNPLLSTSRPLVLGKPNGDTIDYQKQLKQMIKDLAKEKDKMEKELPKMSQREFIQFCKTLYSMFHEDPEENDLYQAIATVTTLLLQIGEVGQRGSSSGSCSQECEEPQASAPPEQDSVFAEAGKSPQAFPETEGDWTVSLEHILASLLTEQSLVNFFEKPLNIKSKLENAKLNQYSLKVLEMSHPPQAELKLNDL", "length": 1134 }, "evidence": [ { "id": "A0A8V0YEF4", "url": "https://omabrowser.org/oma/group/A0A8V0YEF4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YEF4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEF4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "system process", "id": "GO:0003008", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003008", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YEF4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEF4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1080, "end_pos": 1082, "annotation": "n_glycosylation_sequon" }, { "start_pos": 349, "end_pos": 351, "annotation": "n_glycosylation_sequon" }, { "start_pos": 410, "end_pos": 412, "annotation": "n_glycosylation_sequon" }, { "start_pos": 84, "end_pos": 86, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YEF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEF4" }, { "id": "PS50086", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50086" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Rab-GAP TBC", "eco_id": "ECO_0000259", "start_pos": 522, "end_pos": 709, "start_aa": "Gly", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1080, "end_pos": 1082 }, { "start_pos": 349, "end_pos": 351 }, { "start_pos": 410, "end_pos": 412 }, { "start_pos": 84, "end_pos": 86 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YEG3-1", "uniprot_ac": "A0A8V0YEG3", "uniprot_id": "A0A8V0YEG3_CHICK", "mass": { "chemical_mass": 113866.0, "monoisotopic_mass": 113866.0 }, "refseq": {}, "gene_names": [ { "name": "EFR3B", "type": "recommended", "evidence": [ { "id": "A0A8V0YEG3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEG3" } ] } ], "protein_names": [ { "name": "Protein EFR3 homolog B", "type": "recommended", "evidence": [ { "id": "A0A8V0YEG3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEG3/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Component of a complex required to localize phosphatidylinositol 4-kinase (PI4K) to the plasma membrane. The complex acts as a regulator of phosphatidylinositol 4-phosphate (PtdIns(4)P) synthesis. In the complex, EFR3B probably acts as the membrane-anchoring component. Also involved in responsiveness to G-protein-coupled receptors; it is however unclear whether this role is direct or indirect.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YEF7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEF7#function" }, { "database": "UniProtKB", "id": "ARBA00060067", "url": "https://www.uniprot.org/uniprotkb/ARBA00060067#function" }, { "database": "UniProtKB", "id": "A0A8V0YEG3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEG3#function" }, { "database": "UniProtKB", "id": "A0A8V0Y1B4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y1B4#function" }, { "database": "UniProtKB", "id": "A0A8V0Y5X6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5X6#function" }, { "database": "UniProtKB", "id": "A0A8V0Y1B9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y1B9#function" }, { "database": "UniProtKB", "id": "A0A8V0Y5Y3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5Y3#function" }, { "database": "UniProtKB", "id": "A0A8V0Y9S5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9S5#function" }, { "database": "UniProtKB", "id": "A0A8V0Y9T0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9T0#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YEG3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEG3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "EFR3B", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEG3", "locus": { "chromosome": "3", "start_pos": 105189590, "end_pos": 105245970, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010010663", "url": "https://www.ensembl.org/id/ENSGALG00010010663" } ] } } ], "crossref": [ { "id": "A0A8V0YEG3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YEG3", "database": "AlphaFoldDB", "categories": [] }, { "id": "422012", "url": "https://www.ncbi.nlm.nih.gov/gene/422012", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR049152", "url": "https://www.ebi.ac.uk/interpro/entry/IPR049152", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051851", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051851", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:422012", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422012", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0Y1B4", "url": "https://www.orthodb.org/?gene=A0A8V0Y1B4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y1B9", "url": "https://www.orthodb.org/?gene=A0A8V0Y1B9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y5X6", "url": "https://www.orthodb.org/?gene=A0A8V0Y5X6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y5Y3", "url": "https://www.orthodb.org/?gene=A0A8V0Y5Y3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y9S5", "url": "https://www.orthodb.org/?gene=A0A8V0Y9S5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y9T0", "url": "https://www.orthodb.org/?gene=A0A8V0Y9T0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YEF7", "url": "https://www.orthodb.org/?gene=A0A8V0YEF7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YEG3", "url": "https://www.orthodb.org/?gene=A0A8V0YEG3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12444", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12444", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12444:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12444:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF21052", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21052", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0Y1B4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y1B4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y1B4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y1B4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y1B9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y1B9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y1B9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y1B9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y5X6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5X6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y5X6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5X6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y5Y3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5Y3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y5Y3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5Y3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y9S5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9S5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y9S5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9S5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y9T0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9T0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y9T0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9T0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YEF7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEF7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YEF7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEF7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YEG3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEG3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YEG3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEG3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVIVEDFSNHTDSMTAIRPMPPPGPHIPLPVPMSPYLSQQRALIQGILPLLGDSDAEHQRVDAAGHGGDEHDGRQAQRQRDEEGEDEEGLPAHRVAGLGRAREVEAQVAEDLGQDEDPEDVGQEAAGGALGEQPVFAEGEEQHVGGQPSPRCQRRGQLVGGVDRGAREEDVAIEEGGEDHQHQEGLVALATEVGLVEVLQGLGSEGVCGCCGALRPRYKRLVDNIFPEDPEDGLVKTNMEKLTFYALSAPEKLDRIGAYLSERLIRDVSRHRYGYVCIAMEALDQLLMACHCQSINLFVESFLKMVAKLLESEKPNLQILGTNSFVKFANIEEDTPSYHRSYDFFVSRFSEMCHSSHDDLEIRTKIRMSGIKGLQGVVRKTVNDELQANIWDPQHMDKIVPSLLFNLQHVEEAESRSPSPLQATEKEKESPTELAERCLRELLGRAAYGNIKNAITPVLIHLDNHSLWEPKIFATRCFRIIMYSIQPQHSHLVIQQLLGHLDANSKSAATVRAGIVEVLSEAAVIAASGSVGPTVLEVFNTLLRQLRLSIDYALTGSYNCITGVSSKIIKEHEERMFQEAVIKTIGSFASTLPTYQQSEVMAFIMNKVPLPSTQQSIEAGKAGENRNRLTQIMLLKSLLQVSVGFQCSNMLTALPSAFLDRLLSAALMEDAEIRLFVLEILISFIDRHDNRQKFSTISTISDISVLKLKVEKCSRQDSVFMKKHSQQLFRHIYLICKEESNIQAHYEALYSMLVLISIELANEEVVVDLIRLVLAVQEIAQINEDNLTAYNRCALFALGAAYLNLISQLITVPTFCQHIHEVIQMRQKEAPYLLPEDVFVEKPRLSKSLDRLGPEVFFWQSKISEVLGGSGYNADRLSTPYVPQLTDEDRLSKRKSIGETISLQVEVESRNSPEREQRAPAEEITYETLKKAIDSVAVEEQERERRRQVVEKFQKAPFEEIAAHCGARATLLQSKLNQIFEITIRPPPSPSGTITAAYGQPQNHSIPVYEMKFPDLCVY", "length": 1019, "header": "tr|A0A8V0YEG3-1|A0A8V0YEG3_CHICK Isoform 1 of Protein EFR3 homolog B OS=Gallus gallus OX=9031 GN=EFR3B PE=1 SV=1 CANONICAL=A0A8V0YEG3-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Y1B4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEG3/entry#A0A8V0Y1B4-1", "sequence": { "sequence": "MGARCREPCLEISFSLGYFTVQELECCRWALAGVCGCCGALRPRYKRLVDNIFPEDPEDGLVKTNMEKLTFYALSAPEKLDRIGAYLSERLIRDVSRHRYGYVCIAMEALDQLLMACHCQSINLFVESFLKMVAKLLESEKPNLQILGTNSFVKFANIEEDTPSYHRSYDFFVSRFSEMCHSSHDDLEIRTKIRMSGIKGLQGVVRKTVNDELQANIWDPQHMDKIVPSLLFNLQHVEEAESRSPSPLQATEKEKESPTELAERCLRELLGRAAYGNIKNAITPVLIHLDNHSLWEPKIFATRCFRIIMYSIQPQHSHLVIQQLLGHLDANSKSAATVRAGIVEVLSEAAVIAASGSVGPTVLEVFNTLLRQLRLSIDYALTGSYNCITGVSSKIIKEHEERMFQEAVIKTIGSFASTLPTYQQSEVMAFIMNKVPLPSTQQSIEAGKAGENRNRLTQIMLLKSLLQVSVGFQCSNMLTALPSAFLDRLLSAALMEDAEIRLFVLEILISFIDRHDNRQKFSTISTISDISVLKLKVEKCSRQDSVFMKKHSQQLFRHIYLICKEESNIQAHYEALYSMLVLISIELANEEVVVDLIRLVLAVQEIAQINEDNLTAYNRCALFALGAAYLNLISQLITVPTFCQHIHEVIQMRQKEAPYLLPEDVFVEKPRLSKSLDRLGPEVFFWQSKISEVLGGSGYNADRLSTPYVPQLTDEDRLSKRKSIGETISLQVEVESRNSPEREQRAPAEEITYETLKKAIDSVAVEEQERERRRQVVEKFQKAPFEEIAAHCGARATLLQSKLNQIFEITIRPPPSPSGTITAAYGQPQNHSIPVYEMKFPDLCVY", "length": 846, "header": "tr|A0A8V0Y1B4-1|A0A8V0Y1B4_CHICK Computationally mapped isoform of Protein EFR3 homolog B OS=Gallus gallus OX=9031 GN=EFR3B PE=1 SV=1 CANONICAL=A0A8V0YEG3-1" }, "locus": { "chromosome": "3", "start_pos": 105225687, "end_pos": 105191986, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010025394.1", "url": "https://www.ensembl.org/id/ENSGALT00010025394.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010014361.1", "url": "https://www.ensembl.org/id/ENSGALP00010014361.1" } ] } }, { "isoform_ac": "A0A8V0Y1B9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEG3/entry#A0A8V0Y1B9-1", "sequence": { "sequence": "MTGVCGCCGALRPRYKRLVDNIFPEDPEDGLVKTNMEKLTFYALSAPEKLDRIGAYLSERLIRDVSRHRYGYVCIAMEALDQLLMACHCQSINLFVESFLKMVAKLLESEKPNLQILGTNSFVKFANIEEDTPSYHRSYDFFVSRFSEMCHSSHDDLEIRTKIRMSGIKGLQGVVRKTVNDELQANIWDPQHMDKIVPSLLFNLQHVEEAESRSPSPLQATEKEKESPTELAERCLRELLGRAAYGNIKNAITPVLIHLDNHSLWEPKIFATRCFRIIMYSIQPQHSHLVIQQLLGHLDANSKSAATVRAGIVEVLSEAAVIAASGSVGPTVLEVFNTLLRQLRLSIDYALTGSYNCITGVSSKIIKEHEERMFQEAVIKTIGSFASTLPTYQQSEVMAFIMNKVPLPSTQQSIEAGKAGENRNRLTQIMLLKSLLQVSVGFQCSNMLTALPSAFLDRLLSAALMEDAEIRLFVLEILISFIDRHDNRQKFSTISTISDISVLKLKVEKCSRQDSVFMKKHSQQLFRHIYLICKEESNIQAHYEALYSMLVLISIELANEEVVVDLIRLVLAVQEIAQINEDNLTAYNRCALFALGAAYLNLISQLITVPTFCQHIHEVIQMRQKEAPYLLPEDVFVEKPRLSKSLDRLGPEVFFWQSKISEVLGGSGYNADRLSTPYVPQLTDEDRLSKRKSIGETISLQVEVESRNSPEREQRAPAEEITYETLKKAIDSVAVEEQERERRRQVVEKFQKAPFEEIAAHCGARATLLQSKLNQIFEITIRPPPSPSGTITAAYGQPQNHSIPVYEMKFPDLCVY", "length": 816, "header": "tr|A0A8V0Y1B9-1|A0A8V0Y1B9_CHICK Computationally mapped isoform of Protein EFR3 homolog B OS=Gallus gallus OX=9031 GN=EFR3B PE=1 SV=1 CANONICAL=A0A8V0YEG3-1" }, "locus": { "chromosome": "3", "start_pos": 105230314, "end_pos": 105191986, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010025409.1", "url": "https://www.ensembl.org/id/ENSGALT00010025409.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010014366.1", "url": "https://www.ensembl.org/id/ENSGALP00010014366.1" } ] } }, { "isoform_ac": "A0A8V0Y5X6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEG3/entry#A0A8V0Y5X6-1", "sequence": { "sequence": "MHCLSPCVCTLLGWESPLGKDGEWLQFVKFANIEEDTPSYHRSYDFFVSRFSEMCHSSHDDLEIRTKIRMSGIKGLQGVVRKTVNDELQANIWDPQHMDKIVPSLLFNLQHVEEAESRSPSPLQATEKEKESPTELAERCLRELLGRAAYGNIKNAITPVLIHLDNHSLWEPKIFATRCFRIIMYSIQPQHSHLVIQQLLGHLDANSKSAATVRAGIVEVLSEAAVIAASGSVGPTVLEVFNTLLRQLRLSIDYALTGSYNCITGVSSKIIKEHEERMFQEAVIKTIGSFASTLPTYQQSEVMAFIMNKVPLPSTQQSIEAGKAGENRNRLTQIMLLKSLLQVSVGFQCSNMLTALPSAFLDRLLSAALMEDAEIRLFVLEILISFIDRHDNRQKFSTISTISDISVLKLKVEKCSRQDSVFMKKHSQQLFRHIYLICKEESNIQAHYEALYSMLVLISIELANEEVVVDLIRLVLAVQEIAQINEDNLTAYNRCALFALGAAYLNLISQLITVPTFCQHIHEVIQMRQKEAPYLLPEDVFVEKPRLSKSLDRLGPEVFFWQSKISEVLGGSGYNADRLSTPYVPQLTDEDRLSKRKSIGETISLQVEVESRNSPEREQRAPAEEITYETLKKAIVDSVAVEEQERERRRQVVEKFQKAPFEEIAAHCGARATLLQSKLNQIFEITIRPPPSPSGTITAAYGQPQNHSIPVYEMKFPDLCVY", "length": 722, "header": "tr|A0A8V0Y5X6-1|A0A8V0Y5X6_CHICK Computationally mapped isoform of Protein EFR3 homolog B OS=Gallus gallus OX=9031 GN=EFR3B PE=1 SV=1 CANONICAL=A0A8V0YEG3-1" }, "locus": { "chromosome": "3", "start_pos": 105213489, "end_pos": 105191986, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010025377.1", "url": "https://www.ensembl.org/id/ENSGALT00010025377.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010014354.1", "url": "https://www.ensembl.org/id/ENSGALP00010014354.1" } ] } }, { "isoform_ac": "A0A8V0Y5Y3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEG3/entry#A0A8V0Y5Y3-1", "sequence": { "sequence": "MYGVCGCCGALRPRYKRLVDNIFPEDPEDGLVKTNMEKLTFYALSAPEKLDRIGAYLSERLIRDVSRHRYGYVCIAMEALDQLLMACHCQSINLFVESFLKMVAKLLESEKPNLQILGTNSFVKFANIEEDTPSYHRSYDFFVSRFSEMCHSSHDDLEIRTKIRMSGIKGLQGVVRKTVNDELQANIWDPQHMDKIVPSLLFNLQHVEEAESRSPSPLQATEKEKESPTELAERCLRELLGRAAYGNIKNAITPVLIHLDNHSLWEPKIFATRCFRIIMYSIQPQHSHLVIQQLLGHLDANSKSAATVRAGIVEVLSEAAVIAASGSVGPTVLEVFNTLLRQLRLSIDYALTGSYNCITGVSSKIIKEHEERMFQEAVIKTIGSFASTLPTYQQSEVMAFIMNKVPLPSTQQSIEAGKAGENRNRLTQIMLLKSLLQVSVGFQCSNMLTALPSAFLDRLLSAALMEDAEIRLFVLEILISFIDRHDNRQKFSTISTISDISVLKLKVEKCSRQDSVFMKKHSQQLFRHIYLICKEESNIQAHYEALYSMLVLISIELANEEVVVDLIRLVLAVQEIAQINEDNLTAYNRCALFALGAAYLNLISQLITVPTFCQHIHEVIQMRQKEAPYLLPEDVFVEKPRLSKSLDRLGPEVFFWQSKISEVLGGSGYNADRLSTPYVPQLTDEDRLSKRKSIGETISLQVEVESRNSPEREQRAPAEEITYETLKKAIVDSVAVEEQERERRRQVVEKFQKAPFEEIAAHCGARLLCVLQATLLQSKLNQIFEITIRPPPSPSGTITAAYGQPQNHSIPVYEMKFPDLCVY", "length": 823, "header": "tr|A0A8V0Y5Y3-1|A0A8V0Y5Y3_CHICK Computationally mapped isoform of Protein EFR3 homolog B OS=Gallus gallus OX=9031 GN=EFR3B PE=1 SV=1 CANONICAL=A0A8V0YEG3-1" }, "locus": { "chromosome": "3", "start_pos": 105228334, "end_pos": 105191986, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010025407.1", "url": "https://www.ensembl.org/id/ENSGALT00010025407.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010014365.1", "url": "https://www.ensembl.org/id/ENSGALP00010014365.1" } ] } }, { "isoform_ac": "A0A8V0Y9S5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEG3/entry#A0A8V0Y9S5-1", "sequence": { "sequence": "MKGVCGCCGALRPRYKRLVDNIFPEDPEDGLVKTNMEKLTFYALSAPEKLDRIGAYLSERLIRDVSRHRYGYVCIAMEALDQLLMACHCQSINLFVESFLKMVAKLLESEKPNLQILGTNSFVKFANIEEDTPSYHRSYDFFVSRFSEMCHSSHDDLEIRTKIRMSGIKGLQGVVRKTVNDELQANIWDPQHMDKIVPSLLFNLQHVEEAESRSPSPLQATEKEKESPTELAERCLRELLGRAAYGNIKNAITPVLIHLDNHSLWEPKIFATRCFRIIMYSIQPQHSHLVIQQLLGHLDANSKSAATVRAGIVEVLSEAAVIAASGSVGPTVLEVFNTLLRQLRLSIDYALTGSYNCITGVSSKIIKEHEERMFQEAVIKTIGSFASTLPTYQQSEVMAFIMNKVPLPSTQQSIEAGKAGENRNRLTQIMLLKSLLQVSVGFQCSNMLTALPSAFLDRLLSAALMEDAEIRLFVLEILISFIDRHDNRQKFSTISTISDISVLKLKVEKCSRQDSVFMKKHSQQLFRHIYLICKEESNIQAHYEALYSMLVLISIELANEEVVVDLIRLVLAVQEIAQINEDNLTAYNRCALFALGAAYLNLISQLITVPTFCQHIHEVIQMRQKEAPYLLPEDVFVEKPRLSKSLDRLGPEVFFWQSKISEVLGGSGYNADRLSTPYVPQLTDEDRLSKRKSIGETISLQVEVESRNSPEREQRAPAEEITYETLKKAIDSVAVEEQERERRRQVVEKFQKAPFEEIAAHCGARATLLQSKLNQIFEITIRPPPSPSGTITAAYGQPQNHSIPVYEMKFPDLCVY", "length": 816, "header": "tr|A0A8V0Y9S5-1|A0A8V0Y9S5_CHICK Computationally mapped isoform of Protein EFR3 homolog B OS=Gallus gallus OX=9031 GN=EFR3B PE=1 SV=1 CANONICAL=A0A8V0YEG3-1" }, "locus": { "chromosome": "3", "start_pos": 105226137, "end_pos": 105191986, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010025391.1", "url": "https://www.ensembl.org/id/ENSGALT00010025391.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010014358.1", "url": "https://www.ensembl.org/id/ENSGALP00010014358.1" } ] } }, { "isoform_ac": "A0A8V0Y9T0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEG3/entry#A0A8V0Y9T0-1", "sequence": { "sequence": "MYGVCGCCGALRPRYKRLVDNIFPEDPEDGLVKTNMEKLTFYALSAPEKLDRIGAYLSERLIRDVSRHRYGYVCIAMEALDQLLMACHCQSINLFVESFLKMVAKLLESEKPNLQILGTNSFVKFANIEEDTPSYHRSYDFFVSRFSEMCHSSHDDLEIRTKIRMSGIKGLQGVVRKTVNDELQANIWDPQHMDKIVPSLLFNLQHVEEAESRSPSPLQATEKEKESPTELAERCLRELLGRAAYGNIKNAITPVLIHLDNHSLWEPKIFATRCFRIIMYSIQPQHSHLVIQQLLGHLDANSKSAATVRAGIVEVLSEAAVIAASGSVGPTVLEVFNTLLRQLRLSIDYALTGSYNCITGVSSKIIKEHEERMFQEAVIKTIGSFASTLPTYQQSEVMAFIMNKVPLPSTQQSIEAGKAGENRNRLTQIMLLKSLLQVSVGFQCSNMLTALPSAFLDRLLSAALMEDAEIRLFVLEILISFIDRHDNRQKFSTISTISDISVLKLKVEKCSRQDSVFMKKHSQQLFRHIYLICKEESNIQAHYEALYSMLVLISIELANEEVVVDLIRLVLAVQEIAQINEDNLTAYNRCALFALGAAYLNLISQLITVPTFCQHIHEVIQMRQKEAPYLLPEDVFVEKPRLSKSLDRLGPEVFFWQSKISEVLGGSGYNADRLSTPYVPQLTDEDRLSKRKSIGETISLQVEVESRNSPEREQRAPAEEITYETLKKAIVDSVAVEEQERERRRQVVEKFQKAPFEEIAAHCGARATLLQSKLNQIFEITIRPPPSPSGTITAAYGQPQNHSIPVYEMKFPDLCVY", "length": 817, "header": "tr|A0A8V0Y9T0-1|A0A8V0Y9T0_CHICK Computationally mapped isoform of Protein EFR3 homolog B OS=Gallus gallus OX=9031 GN=EFR3B PE=1 SV=1 CANONICAL=A0A8V0YEG3-1" }, "locus": { "chromosome": "3", "start_pos": 105228334, "end_pos": 105191986, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010025404.1", "url": "https://www.ensembl.org/id/ENSGALT00010025404.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010014364.1", "url": "https://www.ensembl.org/id/ENSGALP00010014364.1" } ] } }, { "isoform_ac": "A0A8V0YEF7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEG3/entry#A0A8V0YEF7-1", "sequence": { "sequence": "MALSSWVLSPALQLCAAGPACSWEMLHVAGAGVCGCCGALRPRYKRLVDNIFPEDPEDGLVKTNMEKLTFYALSAPEKLDRIGAYLSERLIRDVSRHRYGYVCIAMEALDQLLMACHCQSINLFVESFLKMVAKLLESEKPNLQILGTNSFVKFANIEEDTPSYHRSYDFFVSRFSEMCHSSHDDLEIRTKIRMSGIKGLQGVVRKTVNDELQANIWDPQHMDKIVPSLLFNLQHVEEAESRSPSPLQATEKEKESPTELAERCLRELLGRAAYGNIKNAITPVLIHLDNHSLWEPKIFATRCFRIIMYSIQPQHSHLVIQQLLGHLDANSKSAATVRAGIVEVLSEAAVIAASGSVGPTVLEVFNTLLRQLRLSIDYALTGSYNCITGVSSKIIKEHEERMFQEAVIKTIGSFASTLPTYQQSEVMAFIMNKVPLPSTQQSIEAGKAGENRNRLTQIMLLKSLLQVSVGFQCSNMLTALPSAFLDRLLSAALMEDAEIRLFVLEILISFIDRHDNRQKFSTISTISDISVLKLKVEKCSRQDSVFMKKHSQQLFRHIYLICKEESNIQAHYEALYSMLVLISIELANEEVVVDLIRLVLAVQEIAQINEDNLTAYNRCALFALGAAYLNLISQLITVPTFCQHIHEVIQMRQKEAPYLLPEDVFVEKPRLSKSLDRLGPEVFFWQSKISEVLGGSGYNADRLSTPYVPQLTDEDRLSKRKSIGETISLQVEVESRNSPEREQRAPAEEITYETLKKAIDSVAVEEQERERRRQVVEKFQKAPFEEIAAHCGARATLLQSKLNQIFEITIRPPPSPSGTITAAYGQPQNHSIPVYEMKFPDLCVY", "length": 845, "header": "tr|A0A8V0YEF7-1|A0A8V0YEG3_CHICK Computationally mapped isoform of Protein EFR3 homolog B OS=Gallus gallus OX=9031 GN=EFR3B PE=1 SV=1 CANONICAL=A0A8V0YEG3-1" }, "locus": { "chromosome": "3", "start_pos": 105220473, "end_pos": 105191986, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010025385.1", "url": "https://www.ensembl.org/id/ENSGALT00010025385.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010014356.1", "url": "https://www.ensembl.org/id/ENSGALP00010014356.1" } ] } }, { "isoform_ac": "A0A8V0YEG3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEG3/entry#A0A8V0YEG3-1", "sequence": { "sequence": "MVIVEDFSNHTDSMTAIRPMPPPGPHIPLPVPMSPYLSQQRALIQGILPLLGDSDAEHQRVDAAGHGGDEHDGRQAQRQRDEEGEDEEGLPAHRVAGLGRAREVEAQVAEDLGQDEDPEDVGQEAAGGALGEQPVFAEGEEQHVGGQPSPRCQRRGQLVGGVDRGAREEDVAIEEGGEDHQHQEGLVALATEVGLVEVLQGLGSEGVCGCCGALRPRYKRLVDNIFPEDPEDGLVKTNMEKLTFYALSAPEKLDRIGAYLSERLIRDVSRHRYGYVCIAMEALDQLLMACHCQSINLFVESFLKMVAKLLESEKPNLQILGTNSFVKFANIEEDTPSYHRSYDFFVSRFSEMCHSSHDDLEIRTKIRMSGIKGLQGVVRKTVNDELQANIWDPQHMDKIVPSLLFNLQHVEEAESRSPSPLQATEKEKESPTELAERCLRELLGRAAYGNIKNAITPVLIHLDNHSLWEPKIFATRCFRIIMYSIQPQHSHLVIQQLLGHLDANSKSAATVRAGIVEVLSEAAVIAASGSVGPTVLEVFNTLLRQLRLSIDYALTGSYNCITGVSSKIIKEHEERMFQEAVIKTIGSFASTLPTYQQSEVMAFIMNKVPLPSTQQSIEAGKAGENRNRLTQIMLLKSLLQVSVGFQCSNMLTALPSAFLDRLLSAALMEDAEIRLFVLEILISFIDRHDNRQKFSTISTISDISVLKLKVEKCSRQDSVFMKKHSQQLFRHIYLICKEESNIQAHYEALYSMLVLISIELANEEVVVDLIRLVLAVQEIAQINEDNLTAYNRCALFALGAAYLNLISQLITVPTFCQHIHEVIQMRQKEAPYLLPEDVFVEKPRLSKSLDRLGPEVFFWQSKISEVLGGSGYNADRLSTPYVPQLTDEDRLSKRKSIGETISLQVEVESRNSPEREQRAPAEEITYETLKKAIDSVAVEEQERERRRQVVEKFQKAPFEEIAAHCGARATLLQSKLNQIFEITIRPPPSPSGTITAAYGQPQNHSIPVYEMKFPDLCVY", "length": 1019, "header": "tr|A0A8V0YEG3-1|A0A8V0YEG3_CHICK Isoform 1 of Protein EFR3 homolog B OS=Gallus gallus OX=9031 GN=EFR3B PE=1 SV=1 CANONICAL=A0A8V0YEG3-1" }, "locus": { "chromosome": "3", "start_pos": 105245771, "end_pos": 105191986, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010025413.1", "url": "https://www.ensembl.org/id/ENSGALT00010025413.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010014367.1", "url": "https://www.ensembl.org/id/ENSGALP00010014367.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 534, "start_aa": "Thr", "end_pos": 534, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr534", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:422012", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422012", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YEG3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEG3" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YEG3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEG3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "protein localization to plasma membrane", "id": "GO:0072659", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072659", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YEG3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEG3" } ], "pmid": "" }, { "name": "phosphatidylinositol phosphate biosynthetic process", "id": "GO:0046854", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046854", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YEG3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEG3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1003, "end_pos": 1005, "annotation": "n_glycosylation_sequon" }, { "start_pos": 464, "end_pos": 466, "annotation": "n_glycosylation_sequon" }, { "start_pos": 786, "end_pos": 788, "annotation": "n_glycosylation_sequon" }, { "start_pos": 9, "end_pos": 11, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 534 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1003, "end_pos": 1005 }, { "start_pos": 464, "end_pos": 466 }, { "start_pos": 786, "end_pos": 788 }, { "start_pos": 9, "end_pos": 11 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YEH0-1", "uniprot_ac": "A0A8V0YEH0", "uniprot_id": "A0A8V0YEH0_CHICK", "mass": { "chemical_mass": 40178.0, "monoisotopic_mass": 40178.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Uncharacterized protein", "type": "synonym", "evidence": [ { "id": "A0A8V0YEH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEH0/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YEH0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEH0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEH0", "locus": {} } ], "crossref": [ { "id": "A0A8V0YEH0", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YEH0", "database": "AlphaFoldDB", "categories": [] }, { "id": "PTHR35001", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR35001", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR35001:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR35001:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YEH0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEH0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YEH0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEH0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "ERKGKERKGKERKGKERKGKERKGKERLGKERKGKERLGKERKGKERKGKERKGKERKGKERKGKERKGKERKGKERKGKERKGKERKGKERKGKERKGKERKGKVGKGWERKGWERKGWERKGWERKGKERKGKERKGKERKGKERKGKERKGKERKGKERKGKERKGKERKGKERKGKERKIWERKGKEMLGKERKGKERKGKERKGKERKGKERKGKERKGKERKGKERKGKERKGKERKIWERKGKEMLGKERKGKERKGWERKGWERKGWKRKGKVGKGRVGKGRVGKGRVGKGKEMLGKQRKGWARKGKVGQGKVGKGKVGKGKERKGWERLG", "length": 339, "header": "tr|A0A8V0YEH0-1|A0A8V0YEH0_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0YEH0-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YEH0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEH0/entry#A0A8V0YEH0-1", "sequence": { "sequence": "ERKGKERKGKERKGKERKGKERKGKERLGKERKGKERLGKERKGKERKGKERKGKERKGKERKGKERKGKERKGKERKGKERKGKERKGKERKGKERKGKERKGKVGKGWERKGWERKGWERKGWERKGKERKGKERKGKERKGKERKGKERKGKERKGKERKGKERKGKERKGKERKGKERKIWERKGKEMLGKERKGKERKGKERKGKERKGKERKGKERKGKERKGKERKGKERKGKERKIWERKGKEMLGKERKGKERKGWERKGWERKGWKRKGKVGKGRVGKGRVGKGRVGKGKEMLGKQRKGWARKGKVGQGKVGKGKVGKGKERKGWERLG", "length": 339, "header": "tr|A0A8V0YEH0-1|A0A8V0YEH0_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0YEH0-1" }, "locus": { "chromosome": "W", "start_pos": 2096837, "end_pos": 2094531, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028043.1", "url": "https://www.ensembl.org/id/ENSGALT00010028043.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016088.1", "url": "https://www.ensembl.org/id/ENSGALP00010016088.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YEH5-1", "uniprot_ac": "A0A8V0YEH5", "uniprot_id": "A0A8V0YEH5_CHICK", "mass": { "chemical_mass": 33347.0, "monoisotopic_mass": 33347.0 }, "refseq": { "ac": "NP_001073204", "name": "protein sprouty homolog 3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001073204" }, "gene_names": [ { "name": "SPRY3", "type": "recommended", "evidence": [ { "id": "A0A8V0YEH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEH5" } ] }, { "name": "SPRY3", "type": "synonym", "evidence": [ { "id": "NP_001073204", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001073204" } ] } ], "protein_names": [ { "name": "Sprouty RTK signaling antagonist 3", "type": "synonym", "evidence": [ { "id": "A0A8V0YEH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEH5/entry#names_and_taxonomy" } ] }, { "name": "protein sprouty homolog 3", "type": "synonym", "evidence": [ { "id": "NP_001073204", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001073204" } ] }, { "name": "sprouty homolog 3", "type": "synonym", "evidence": [ { "id": "NP_001073204", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001073204" } ] }, { "name": "sprouty-like protein 3", "type": "synonym", "evidence": [ { "id": "NP_001073204", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001073204" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## inferred exon combination :: based on alignments, homology ##RefSeq-Attributes-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000071.1. On or before Dec 15, 2021 this sequence version replaced XP_015133800.1, NP_001073204.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001073204", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001073204" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YEH5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEH5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SPRY3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEH5", "locus": { "chromosome": "4", "start_pos": 11005480, "end_pos": 10981546, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010011723", "url": "https://www.ensembl.org/id/ENSGALG00010011723" } ] } } ], "crossref": [ { "id": "428712", "url": "https://www.ncbi.nlm.nih.gov/gene/428712", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR007875", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007875", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051192", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051192", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:428712", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:428712", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CQNHTNT", "url": "https://omabrowser.org/oma/group/CQNHTNT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YEH5", "url": "https://www.orthodb.org/?gene=A0A8V0YEH5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12365", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12365", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12365:SF9", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12365:SF9", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05210", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05210", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001073204", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001073204", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YEH5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEH5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YEH5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEH5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQLSSSVAELSCDETMDPPAEDFQQVLSIDQIRSIRASNNYVERPATCFQQARSNPSLSQPPHKQEWTQDRLASSTLQDLHRSHSQQPHMPPLQQAMSHSSTASSVSQSTTASEQRLLSALTPSHSGHSLIRTQPRAGELKAEESPLKGAVEKGSLHGGHLFVCEECGRCKCARCTAARGLPSCWLCNQRCLCSPESLLDYGTCLCCVKGLFYHCSSDDEDTCADDPCSCGPGSCCARWAAMSFLSLLMPCLCCYFPTLGCLKLCQRGYDGLKRPGCRCQTHTNTVCRKISSSSGTPFPKALDKPV", "length": 306, "header": "tr|A0A8V0YEH5-1|A0A8V0YEH5_CHICK Isoform 1 of Sprouty RTK signaling antagonist 3 OS=Gallus gallus OX=9031 GN=SPRY3 PE=3 SV=1 CANONICAL=A0A8V0YEH5-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YEH5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEH5/entry#A0A8V0YEH5-1", "sequence": { "sequence": "MQLSSSVAELSCDETMDPPAEDFQQVLSIDQIRSIRASNNYVERPATCFQQARSNPSLSQPPHKQEWTQDRLASSTLQDLHRSHSQQPHMPPLQQAMSHSSTASSVSQSTTASEQRLLSALTPSHSGHSLIRTQPRAGELKAEESPLKGAVEKGSLHGGHLFVCEECGRCKCARCTAARGLPSCWLCNQRCLCSPESLLDYGTCLCCVKGLFYHCSSDDEDTCADDPCSCGPGSCCARWAAMSFLSLLMPCLCCYFPTLGCLKLCQRGYDGLKRPGCRCQTHTNTVCRKISSSSGTPFPKALDKPV", "length": 306, "header": "tr|A0A8V0YEH5-1|A0A8V0YEH5_CHICK Isoform 1 of Sprouty RTK signaling antagonist 3 OS=Gallus gallus OX=9031 GN=SPRY3 PE=3 SV=1 CANONICAL=A0A8V0YEH5-1" }, "locus": { "chromosome": "4", "start_pos": 10987787, "end_pos": 10986870, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028039.1", "url": "https://www.ensembl.org/id/ENSGALT00010028039.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016084.1", "url": "https://www.ensembl.org/id/ENSGALP00010016084.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:428712", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:428712", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287A5X6-1", "protein_name": "Sprouty RTK signaling antagonist 3", "gene_name": "SPRY3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDAAVADDCQQILPIEQLRSTHASNDYVDRPPVPCKQALSSPSLIVHTHKSDWSLATMPTALPRSLSQCHQLQPLPQHLSQSSIASSMSHSTTASDQRLLASITPSPSGQSIIRTQPGTGAHPKADGALKGEAEPSAEHPSEHLFICEECGRCKCVLCTAARPLPSCWLCNQRCLCSAESLLDYGTCLCCVKGLFYHCSTDDEDNCADEPCSCGPGSCFVRWAAMSLISLFLPCLCCYLPTRGCLHLCQQGYDSLRRPGCRCKRHTNTVCRKISSGSAPFPKAQEKSV", "length": 288 }, "evidence": [ { "id": "A0A8V0YEH5", "url": "https://omabrowser.org/oma/group/A0A8V0YEH5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0AAA9SGL1-1", "protein_name": "Sprouty RTK signaling antagonist 3", "gene_name": "SPRY3", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MDAAVTDDFQQILPIEQLRSTHASNDYVDRPPVPCKQALSSPSLIVQTHKSDWSLATMPTALPRSLSQCHQLQPLPQHLSQSSIASSMSHSTTASDQRLLASITPSPSGQSIIRTQPGTGAHPKADGALKGEAEHSAMHPSEHLFICEECGRCKCVLCTAARPLPACWLCNQRCLCSAESLLDYGTCLCCVKGLFYHCSTDDEDNCADEPCSCGPGSCFVRWAAMSLISLFLPCLCCYLPTRGCLHLCQQGYDSLRRPGCRCKRHTNTVCRKISSGSAPFPKAQEKSV", "length": 288 }, "evidence": [ { "id": "A0A8V0YEH5", "url": "https://omabrowser.org/oma/group/A0A8V0YEH5/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "B5DF90-1", "protein_name": "Sprouty RTK signaling antagonist 3", "gene_name": "Spry3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MATDDPQPILPIAQLRSVHASNDYVDRPPAPRKPTLSSPSLTLQTHKSDWSLATTPTALPRSVSQCHQLQPLPQHLSQSSIASSVSQTTTASDQRLLATMTPSPSGPSSILRTHPKVDGALKGGAEQSAGQSSDHRLFICEECGRCKCVPCTAVRPLPSCWVCNQRCLCSAESLLDYGTCLCCVQGVFYHCSTDDEDNCADEPCSCGPGSRFLRWAAMGVISVFLPCLCCYLPTRGCLRLCQRGYDSLRRPGCRCKMHTNTVCRKMSSGGSPCPKAQEKSV", "length": 281 }, "evidence": [ { "id": "A0A8V0YEH5", "url": "https://omabrowser.org/oma/group/A0A8V0YEH5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O43610-1", "protein_name": "Protein sprouty homolog 3", "gene_name": "SPRY3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDAAVTDDFQQILPIEQLRSTHASNDYVERPPAPCKQALSSPSLIVQTHKSDWSLATMPTSLPRSLSQCHQLQPLPQHLSQSSIASSMSHSTTASDQRLLASITPSPSGQSIIRTQPGAGVHPKADGALKGEAEQSAGHPSEHLFICEECGRCKCVPCTAARPLPSCWLCNQRCLCSAESLLDYGTCLCCVKGLFYHCSTDDEDNCADEPCSCGPSSCFVRWAAMSLISLFLPCLCCYLPTRGCLHLCQQGYDSLRRPGCRCKRHTNTVCRKISSGSAPFPKAQEKSV", "length": 288 }, "evidence": [ { "id": "A0A8V0YEH5", "url": "https://omabrowser.org/oma/group/A0A8V0YEH5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "negative regulation of Ras protein signal transduction", "id": "GO:0046580", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046580", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YEH5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEH5" } ], "pmid": "" }, { "name": "negative regulation of ERK1 and ERK2 cascade", "id": "GO:0070373", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070373", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YEH5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEH5" } ], "pmid": "" }, { "name": "negative regulation of epidermal growth factor receptor signaling pathway", "id": "GO:0042059", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042059", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YEH5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEH5" } ], "pmid": "" }, { "name": "negative regulation of fibroblast growth factor receptor signaling pathway", "id": "GO:0040037", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0040037", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YEH5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEH5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YEH5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEH5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "protein kinase inhibitor activity", "id": "GO:0004860", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004860", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YEH5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEH5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": 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"uniprot_ac": "A0A8V0YEI5", "uniprot_id": "A0A8V0YEI5_CHICK", "mass": { "chemical_mass": 194907.0, "monoisotopic_mass": 194907.0 }, "refseq": { "ac": "XP_040511582", "name": "rho guanine nucleotide exchange factor 28", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040511582" }, "gene_names": [ { "name": "ARHGEF28", "type": "recommended", "evidence": [ { "id": "A0A8V0YEI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEI5" } ] }, { "name": "ARHGEF28", "type": "synonym", "evidence": [ { "id": "XP_040511582", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040511582" } ] } ], "protein_names": [ { "name": "Rho guanine nucleotide exchange factor 28", "type": "synonym", "evidence": [ { "id": "A0A8V0YEI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEI5/entry#names_and_taxonomy" } ] }, { "name": "rho guanine nucleotide exchange factor 28", "type": "synonym", "evidence": [ { "id": "XP_040511582", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040511582" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052572.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040511582", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040511582" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YEI5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEI5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ARHGEF28", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEI5", "locus": { "chromosome": "Z", "start_pos": 25125102, "end_pos": 25254405, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010011724", "url": "https://www.ensembl.org/id/ENSGALG00010011724" } ] } } ], "crossref": [ { "id": "cd00160", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00160", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd20876", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd20876", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "427201", "url": "https://www.ncbi.nlm.nih.gov/gene/427201", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000219", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000219", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001849", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001849", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002219", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002219", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035899", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035899", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036770", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036770", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041020", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041020", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046349", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046349", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051632", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051632", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "SFCHENS", "url": "https://omabrowser.org/oma/group/SFCHENS/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YAU0", "url": "https://www.orthodb.org/?gene=A0A8V0YAU0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YEI5", "url": "https://www.orthodb.org/?gene=A0A8V0YEI5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YEJ0", "url": "https://www.orthodb.org/?gene=A0A8V0YEJ0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13944", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13944", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13944:SF22", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13944:SF22", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00130", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00130", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00621", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00621", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17838", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17838", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-3928662", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3928662", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-8980692", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8980692", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9013026", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013026", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9013106", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013106", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_040511582", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040511582", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YAU0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAU0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YAU0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAU0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YEI5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEI5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YEI5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEI5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YEJ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEJ0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YEJ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEJ0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MELSCTEVPLYGQVTISAKFDKGIYLPEDAEFYFVYDGSMKRHIMFAERIGDNALQSLVPGHGCQEAVSVSVLMYSRGSSPVALGSCPVTYRENLSCKLSRFLISHTECISTTSHKVLLDKFGLTVKDLQSLDTDLTMAIAHEELPSTWSILGSCYEGEPTHKETLLHLAMKLGLVKLSEFLVGQPGGTLALALPNEDGATPLDLAEQNGHSKLVEVFSNFQGSRSPDVARVEISKGACMSFVRSSAALTLTLDHTAKHLLESDVRLFRKYFWNRPLLHECINSNQLEPVEDPVMRCSTTNSVEGPVSLAPDDLSQDGEKPFHGAVVPSKEVEDNVLLDIAQRHSTLDILKKLKTPPTFFAAARLSTMLNGSDEVYANCMLVDQAEDLKMNYIHGDSISSETCLNPSSSAPVVKSSSSPSLEENDQYRCDPNEGNQSVKNEGNTGLRPTVSPSDLYEADSYLPFKTNEFIKEQGQLHAVMKKKSSSLDDLEVNSRSEGVLGRSNIPYPLLEHPEVKACSRDGLDSSEMNISRTESLPLSISPQTKECSPSGIRSRSYSCSSPKDSLGRPRILQDFTVGDSGEDGVPMNSGRSLLQALSLSKSVSLLHPCKRAYSLPEHSREKRIQEEEWDKYIVPSKTESEKYKVSRTFSFLMNRMTSTRNKYKTKNKDTKDKEKLNRHNFINGTFSGIMPCMACEKALLGKESLQCSYCNVIVHKNCKECVPVCTKKSQERYHSKNKPQVGIGNLSFGDISQPGISSVHPSSSVPIVSAGRREALQQSHSLSKSVPGASFERRSMPFPEQDSDASTWRTKSRSEEMLQALGTYSSMDSFVMEVEVDSSQWTDISSDAHEFEAESWSLVVDPMFCNKQEKDVAKRQDVIFELMQTEVHHIHTLFIMSEIFRKGMKEELQLDHSTVDRIFPCLDELLEIHRQFFCRMRERRQESCEEGNERNFVISRIGDILVQQFSEENATKMKKIYGEFCSHQKEAVNLFKELQQNKKFQNFIKLRNSNLLARRRGIPECILLVTQRITKYPVLVERILQYTKEGTEEHKDLCKALRLIKDMIAAVDLKVNEYEKRQKLMEILNRTENKTYTKLKSGHIFRKQDLMRKERILLHEGLVYWKTATGRFKDTLALLLTDMLLFLQEKDQKYVFAAVDQKPSVISLQKLIVREVANEERGMFLISASSAGPEMYEVHTNSREERNSWMRHIQDAVESCPEEQEEGKIGEFDEDRRIAEAKACKIQKCQESLSNQDQQICSCLEDKLHIYAELVDMSGFEDVHVEPHLLIKPDYGETPQASSLLVAALREVESLHVALTSSQVNETDRSSEESTEELTLKHRLSASEILESFPGDAETKEVEESPEVDLSACSIEKEISDASVEYKGESTSFPGSTGTEIVQAIQNLTRLLYSIQAALAIQDSHRELHRLLLQENEKTSRGHSSRIPLFLEPEKYRNSEKQREELANISKLQQQFQQEQQRWLRECEQRQQELEVRAGLLEQREQACSCQEELLEKSRQGLALQSQEFQQSLERLREGQKLLEKKRDSIKMQKKLLWHWKHGLQSSLLLPTGSHEIMGHDQLDSLHGENAFYLNEAVVRVSLSGLNRSDSSLVYEDGVYGLGISDLDMARTCENQVNLRVDTPYQPALTNELWKSTGPYQQMSFSCKSNKDAFNNDLNASQTQGPQAGSPNHGSIQPPQVEPLMLNHQPESLQDAEGGDGREENIVYL", "length": 1725, "header": "tr|A0A8V0YEI5-1|A0A8V0YEI5_CHICK Isoform 1 of Rho guanine nucleotide exchange factor 28 OS=Gallus gallus OX=9031 GN=ARHGEF28 PE=1 SV=1 CANONICAL=A0A8V0YEI5-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YAU0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEI5/entry#A0A8V0YAU0-1", "sequence": { "sequence": "MDSDSDSPFNYSWPSLPKMRIRRRASKQAQRHSTLDILKKLKTPPTFFAAARLSTMLNGSDEVYANCMLVDQAEDLKMNYIHGDSISSETCLNPSSSAPVVKSSSSPSLEENDQYRCDPNEGNQSVKNEGNTGLRPTVSPSDLYEADSYLPFKTNEFIKEQGQLHAVMKKKSSSLDDLEVNSRSEGVLGRSNIPYPLLEHPEVKACSRDGLDSSEMNISRTESLPLSISPQTKECSPSGIRSRSYSCSSPKDSLGRPRILQDFTVGDSGEDGVPMNSGRSLLQALSLSKSVSLLHPCKRAYSLPEHSREKRIQEEEWDKYIVPSKTESEKYKVSRTFSFLMNRMTSTRNKYKTKNKDTKDKEKLNRHNFINGTFSGIMPCMACEKALLGKESLQCSYCNVIVHKNCKECVPVCTKKSQERYHSKNKPQVGIGNLSFGDISQPGISSVHPSSSVPIVSAGRREALQQSHSLSKSVPGASFERRSMPFPEQDSDASTWRTKSRSEEMLQALGTYSSMDSFVMEVEVDSSQWTDISSDAHEFEAESWSLVVDPMFCNKQEKDVAKRQDVIFELMQTEVHHIHTLFIMSEIFRKGMKEELQLDHSTVDRIFPCLDELLEIHRQFFCRMRERRQESCEEGNERNFVISRIGDILVQQFSEENATKMKKIYGEFCSHQKEAVNLFKELQQNKKFQNFIKLRNSNLLARRRGIPECILLVTQRITKYPVLVERILQYTKEGTEEHKDLCKALRLIKDMIAAVDLKVNEYEKRQKLMEILNRTENKTYTKLKSGHIFRKQDLMRKERILLHEGLVYWKTATGRFKDTLALLLTDMLLFLQEKDQKYVFAAVDQKPSVISLQKLIVREVANEERGMFLISASSAGPEMYEVHTNSREERNSWMRHIQDAVESCPEEQEEGKIGEFDEDRRIAEAKACKIQKCQESLSNQDQQICSCLEDKLHIYAELVDMSGFEDVHVEPHLLIKPDYGETPQASSLLVAALREVESLHVALTSSQVNETDRSSEESTEELTLKHRLSASEILESFPGDAETKEVEESPEVDLSACSIEKEISDASVEYKGESTSFPGSTGTEIVQAIQNLTRLLYSIQAALAIQDSHRELHRLLLQENEKTSRGHSSRIPLFLEPEKYRNSEKQREELANISKLQQQFQQEQQRWLRECEQRQQELEVRAGLLEQREQACSCQEELLEKSRQGLALQSQEFQQSLERLREGQKLLEKKRDSIKMQKKLLWHWKHGLQSSLLLPTGSHEIMGHDQLDSLHGENAFYLNEAVVRVSLSGLNRSDSSLVYEDGVYGLGISDLDMARTCENQVNLRVDTPYQPALTNELWKSTGPYQQMSFSCKSNKDAFNNDLNASQTQGPQAGSPNHGSIQPPQVEPLMLNHQPESLQDAEGGDGREENIVYL", "length": 1413, "header": "tr|A0A8V0YAU0-1|A0A8V0YAU0_CHICK Computationally mapped isoform of Rho guanine nucleotide exchange factor 28 OS=Gallus gallus OX=9031 GN=ARHGEF28 PE=1 SV=1 CANONICAL=A0A8V0YEI5-1" }, "locus": { "chromosome": "Z", "start_pos": 25188439, "end_pos": 25126257, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028051.1", "url": "https://www.ensembl.org/id/ENSGALT00010028051.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016094.1", "url": "https://www.ensembl.org/id/ENSGALP00010016094.1" } ] } }, { "isoform_ac": "A0A8V0YEI5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEI5/entry#A0A8V0YEI5-1", "sequence": { "sequence": "MELSCTEVPLYGQVTISAKFDKGIYLPEDAEFYFVYDGSMKRHIMFAERIGDNALQSLVPGHGCQEAVSVSVLMYSRGSSPVALGSCPVTYRENLSCKLSRFLISHTECISTTSHKVLLDKFGLTVKDLQSLDTDLTMAIAHEELPSTWSILGSCYEGEPTHKETLLHLAMKLGLVKLSEFLVGQPGGTLALALPNEDGATPLDLAEQNGHSKLVEVFSNFQGSRSPDVARVEISKGACMSFVRSSAALTLTLDHTAKHLLESDVRLFRKYFWNRPLLHECINSNQLEPVEDPVMRCSTTNSVEGPVSLAPDDLSQDGEKPFHGAVVPSKEVEDNVLLDIAQRHSTLDILKKLKTPPTFFAAARLSTMLNGSDEVYANCMLVDQAEDLKMNYIHGDSISSETCLNPSSSAPVVKSSSSPSLEENDQYRCDPNEGNQSVKNEGNTGLRPTVSPSDLYEADSYLPFKTNEFIKEQGQLHAVMKKKSSSLDDLEVNSRSEGVLGRSNIPYPLLEHPEVKACSRDGLDSSEMNISRTESLPLSISPQTKECSPSGIRSRSYSCSSPKDSLGRPRILQDFTVGDSGEDGVPMNSGRSLLQALSLSKSVSLLHPCKRAYSLPEHSREKRIQEEEWDKYIVPSKTESEKYKVSRTFSFLMNRMTSTRNKYKTKNKDTKDKEKLNRHNFINGTFSGIMPCMACEKALLGKESLQCSYCNVIVHKNCKECVPVCTKKSQERYHSKNKPQVGIGNLSFGDISQPGISSVHPSSSVPIVSAGRREALQQSHSLSKSVPGASFERRSMPFPEQDSDASTWRTKSRSEEMLQALGTYSSMDSFVMEVEVDSSQWTDISSDAHEFEAESWSLVVDPMFCNKQEKDVAKRQDVIFELMQTEVHHIHTLFIMSEIFRKGMKEELQLDHSTVDRIFPCLDELLEIHRQFFCRMRERRQESCEEGNERNFVISRIGDILVQQFSEENATKMKKIYGEFCSHQKEAVNLFKELQQNKKFQNFIKLRNSNLLARRRGIPECILLVTQRITKYPVLVERILQYTKEGTEEHKDLCKALRLIKDMIAAVDLKVNEYEKRQKLMEILNRTENKTYTKLKSGHIFRKQDLMRKERILLHEGLVYWKTATGRFKDTLALLLTDMLLFLQEKDQKYVFAAVDQKPSVISLQKLIVREVANEERGMFLISASSAGPEMYEVHTNSREERNSWMRHIQDAVESCPEEQEEGKIGEFDEDRRIAEAKACKIQKCQESLSNQDQQICSCLEDKLHIYAELVDMSGFEDVHVEPHLLIKPDYGETPQASSLLVAALREVESLHVALTSSQVNETDRSSEESTEELTLKHRLSASEILESFPGDAETKEVEESPEVDLSACSIEKEISDASVEYKGESTSFPGSTGTEIVQAIQNLTRLLYSIQAALAIQDSHRELHRLLLQENEKTSRGHSSRIPLFLEPEKYRNSEKQREELANISKLQQQFQQEQQRWLRECEQRQQELEVRAGLLEQREQACSCQEELLEKSRQGLALQSQEFQQSLERLREGQKLLEKKRDSIKMQKKLLWHWKHGLQSSLLLPTGSHEIMGHDQLDSLHGENAFYLNEAVVRVSLSGLNRSDSSLVYEDGVYGLGISDLDMARTCENQVNLRVDTPYQPALTNELWKSTGPYQQMSFSCKSNKDAFNNDLNASQTQGPQAGSPNHGSIQPPQVEPLMLNHQPESLQDAEGGDGREENIVYL", "length": 1725, "header": "tr|A0A8V0YEI5-1|A0A8V0YEI5_CHICK Isoform 1 of Rho guanine nucleotide exchange factor 28 OS=Gallus gallus OX=9031 GN=ARHGEF28 PE=1 SV=1 CANONICAL=A0A8V0YEI5-1" }, "locus": { "chromosome": "Z", "start_pos": 25246692, "end_pos": 25126257, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028064.1", "url": "https://www.ensembl.org/id/ENSGALT00010028064.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016103.1", "url": "https://www.ensembl.org/id/ENSGALP00010016103.1" } ] } }, { "isoform_ac": "A0A8V0YEJ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEI5/entry#A0A8V0YEJ0-1", "sequence": { "sequence": "MELSCTEVPLYGQVTISAKFDKGIYLPEDAEFYFVYDGSMKRHIMFAERIGDNALQSLVPGHGCQEAVSVSVLMYSRGSSPVALGSCPVTYRENLSCKLSRFLISHTECISTTSHKVLLDKFGLTVKDLQSLDTDLTMAIAHEELPSTWSILGSCYEGEPTHKETLLHLAMKLGLVKLSEFLVGQPGGTLALALPNEDGATPLDLAEQNGHSKLVEVFSNFQGSRSPDVARVEISKGACMSFVRSSAALTLTLDHTAKHLLESDVRLFRKYFWNRPLLHECINSNQLEPVEDPVMRCSTTNSVEGPVSLAPDDLSQDGEKPFHGAVVPSKEVEDNVLLDIAQRHSTLDILKKLKTPPTFFAAARLSTMLNGSDEVYANCMLVDQAEDLKMNYIHGDSISSETCLNPSSSAPVVKSSSSPSLEENDQYRCDPNEGNQSVKNEGNTGLRPTVSPSDLYEADSYLPFKTNEFIKEQGQLHAVMKKKSSSLDDLEVNSRSEGVLGRSNIPYPLLEHPEVKACSRDGLDSSEMNISRTESLPLSISPQTKECSPSGIRSRSYSCSSPKDSLGRPRILQDFTVGDSGEERAYSLPEHSREKRIQEEEWDKYIVPSKTESEKYKVSRTFSFLMNRMTSTRNKYKTKNKDTKDKEKLNRHNFINGTFSGIMPCMACEKALLGKESLQCSYCNVIVHKNCKECVPVCTKKSQERYHSKNKPQVGIGNLSFGDISQPGISSVHPSSSVPIVSAGRREALQQSHSLSKSVPGASFERRSMPFPEQDSDASTWRTKSRSEEMLQALGTYSSMDSFVMEVEVDSSQWTDISSDAHEFEAESWSLVVDPMFCNKQEKDVAKRQDVIFELMQTEVHHIHTLFIMSEIFRKGMKEELQLDHSTVDRIFPCLDELLEIHRQFFCRMRERRQESCEEGNERNFVISRIGDILVQQFSEENATKMKKIYGEFCSHQKEAVNLFKELQQNKKFQNFIKLRNSNLLARRRGIPECILLVTQRITKYPVLVERILQYTKEGTEEHKDLCKALRLIKDMIAAVDLKVNEYEKRQKLMEILNRTENKTYTKLKSGHIFRKQDLMRKERILLHEGLVYWKTATGRFKDTLALLLTDMLLFLQEKDQKYVFAAVDQKPSVISLQKLIVREVANEERGMFLISASSAGPEMYEVHTNSREERNSWMRHIQDAVESCPEEQEEGKIGEFDEDRRIAEAKACKIQKCQESLSNQDQQICSCLEDKLHIYAELVDMSGFEDVHVEPHLLIKPDYGETPQASSLLVAALREVESLHVALTSSQVNETDRSSEESTEELTLKHRLSASEILESFPGDAETKEVEESPEVDLSACSIEKEISDASVEYKGESTSFPGSTGTEIVQAIQNLTRLLYSIQAALAIQDSHRELHRLLLQENEKTSRGHSSRIPLFLEPEKYRNSEKQREELANISKLQQQFQQEQQRWLRECEQRQQELEVRAGLLEQREQACSCQEELLEKSRQGLALQSQEFQQSLERLREGQKLLEKKRDSIKMQKKLLWHWKHGLQSSLLLPTGSHEIMGHDQLDSLHGENAFYLNEAVVRVSLSGLNRSDSSLVYEDGVYGLGISDLDMARTCENQVNLRVDTPYQPALTNELWKSTGPYQQMSFSCKSNKDAFNNDLNASQTQGPQAGSPNHGSIQPPQVEPLMLNHQPESLQDAEGGDGREENIVYL", "length": 1698, "header": "tr|A0A8V0YEJ0-1|A0A8V0YEJ0_CHICK Computationally mapped isoform of Rho guanine nucleotide exchange factor 28 OS=Gallus gallus OX=9031 GN=ARHGEF28 PE=1 SV=1 CANONICAL=A0A8V0YEI5-1" }, "locus": { "chromosome": "Z", "start_pos": 25246692, "end_pos": 25126257, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028073.1", "url": "https://www.ensembl.org/id/ENSGALT00010028073.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016108.1", "url": "https://www.ensembl.org/id/ENSGALP00010016108.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-3928662", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3928662", "resource": "Reactome", "description": "EPHB-mediated forward signaling" }, { "id": "R-GGA-8980692", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8980692", "resource": "Reactome", "description": "RHOA GTPase cycle" }, { "id": "R-GGA-9013026", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013026", "resource": "Reactome", "description": "RHOB GTPase cycle" }, { "id": "R-GGA-9013106", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013106", "resource": "Reactome", "description": "RHOC GTPase cycle" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A286ZQN4-1", "protein_name": "Rho guanine nucleotide exchange factor 28", "gene_name": "ARHGEF28", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MELNCSEVPLYGQMTVYAKFGKNVYLPKDAEFYFIYNGSHQRHIVIAERTADNVLQSSVPGHGLQETVTVSVCLCSEGYSPVTMGSDAVTYVDNLACRLARLLVTQADRLTASSHQTLLTPFALTEGALPALDEELVLALTHLELPVGWTVLGNSSLEVSLHRESLLHLAVRWGLTKLSQFLLCLPGGIQALALPNEEGATPIDLALRGGHSKLVEDLTNFQGRRSPGFSRVQLSEGASLQYIHSSETLTLTLNHTADHLVEADIKLFRKYFWDRAFLIKALEEQEARSEEKLDMPSSAAESEEEIKNLVSSRSSPGKESVKCVESPVVQLNEGEGQDGLDLDRFSDVLRKSKRPPLLLAAGRPSDMLNGGDEVYANCMVIDQVGDLDVNYVNIEGITPDTSPESMGSTLGSESSKHILPTETSSGMYPPHGNKDVILHPEAQRSFMSPSSSYASNLNLSFGLHGFEKEQSHLKRRSSSLDALDADSEGEGHSAQSHLCHTPVSQSSSRTGLPSGDELDSFETNTEPDFNISRTESLSLSSSLQLKESLLSGVRSRSYSCSSPKISLGKTRLIRDFTVCNSVEEQRAYSLPEPPREKRIQEEEWDKCIIPAKSESEKYKVSRTFSFLMNRMTSPRNKSKTKGKDAKDKEKLSRHQFVPGTFSGVLPCWVCDKTLLGKESFQCSNCNANVHKGCKDAAPPCNKKFQEKYNKNKPQTILGNSSLRDGPPPGLSLHPSSSMPIGLPTGRKEMASQVHPLSRSVPGTALESFRRSGTSLESESDGSTWRSRSHSDELFQPMGSSPSTDSLLMEDVVDSSLWSDLSGDAQELEAESWSLVVDPSFCSKQEKDVIKRQDVIFELMQTEMHHIQTLFIMSEIFRKGMKEELQLDHSTVDKIFPCLDELLEIHRHFFYSMKERRQESCIGNDRNFVINRIGDILVQQFSEENANKMKKIYGEFCSHHKEAVSLFKELQQNKKFQNFIKLRNSNLLARRRGIPECILLVTQRITKYPVLVERILQYTKESTEEQKDLCKALCLIKDMIAAVDLKVSEYEKKQKWLEILSKIENKTYTKLKNGHVFRKQALMSKERTLLYEGLVYWKTATGRFKDILALLLTDVLLFLQEKDQKYIFAAVDQKPSVISLQKLIAREVANEERGMFLISASSAGPEMYEIHTNSKEERNAWMRRIQQAVESCPEEEGGKTSESDEERRRAEVRVAKIQQCQEILSNQDQQICAYLEEKLHIYAELGELSGFEDVHLEPHLLIKLDPGEPPQAASLLAAALKEAESLQVAVKVSQVSDACQPPEEGCAEPAVTDVLSSRDAAGSPTASLVTEGTGGRGCWDVDPGTQGVGTDQAVSDAGEKVECRSFPGSSQSEIIQAIQNLTRLLYSLQAALTIQDSHIEIHKLVLQQQESVCSGPSFRGSPLQDQEKYRNLEKRREELASIHKLQHQFLQDQQRWHRRCDQQQREQEAKASRLQAREQECQAQEELLLRNREELDQQLQEYQQNLERLREGQRLVERERERMRAQQSLLCGWKHSRQSSLPAAFSPGRMELMELNRSENFCHENSFFINEALVQMSLNTFNKPTPSDATYPPDISHSDLVRTCGNQVALKTDVSRPSDVNHEPWVAAGPCHQIPPLHQSSKDSCENDLDISQTENSPPHDSNPHGPQLQTFIAEAKLSLQRVTTPDGETGDGEENIVYL", "length": 1699 }, "evidence": [ { "id": "A0A8V0YEI5", "url": "https://omabrowser.org/oma/group/A0A8V0YEI5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P0C6P5-1", "protein_name": "Rho guanine nucleotide exchange factor 28", "gene_name": "Arhgef28", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MELSCSEVPLYGQRTVYAKFGKNVYLPEDAEFYFIYDGSHQRHVVIADRVEDNVLQSIIPGHWLQETVMVSVCLCSEGYSPVTMGSGSVTYVDNMACRLARLLVTQADRLTPCSHQTLLTPFALTAEALPALDEELVLALTQLELPLGWTVLGNSSLEVCLHRESLLHLAVRWALPKLFHFLLCLPGGVKALELPNEEATTPLDLALHGGHSMLVEDISNFQGRRSPGFSRLRLNEDATLQFDRSSETLTLTVNHTAEHLLEADIKLFRKYFWDRAFLVKALDQEAKTERATMPSGAAETEEEVRNLESGRSPSEEEEDGQLVKSQADGPSEQEDQDRLVLDHSFDGLKKSKHAPASLAAGQLSDVPNGGDEVYANCMVIDQVGDLDINYINIEGLSTHTSPESMRSTLGPQACKHILPPDTSPCGHLLCEDSDRTLDAAASQSCMSPPSSHTSNLNLSFGLHGFVKEQSHLKKRSSSLDALVADSEEEGRSEPPICYAVGSQSSPRTGLPGGDELDSFDANTEPDCNISRTESLSLSSTLHSKESLLSGIRSRSYSCSSPKISSGKSRLVRDFTVCSSSEEQRSYSFQEPPGEKRIQEEEWDDYIIPAKAESEKHKVSRTFSFLMNRMTSPRNKSKMKNKDTKDKEKLNRHQFVPGTFSGVLQCSGCDKTLLGKESLQCANCKANTHKGCKDTVPPCTKKFQDKYNKNKPQTILGSSSVRDVPPPGLSLHPSPSMPIGLPAGRKETAGQAHPLSRSVPGTTLESFRRAVTSLESEGDSNSWRSRSHSDELFQSMGSSPSTESFMMEDVVDSSLWSELSSDAQEFEAESWSLVVDPSFCSRQEKDVIKRQDVIFELMQTEVHHIQTLLIMSEVFRKGMKEELQLDHSTVDRIFPCLDELLETHKHFFFSMKERRQESCTGNDRNFVINQIGDILVQQFSEENASKMKRIYGDFCSHHKEAMSLFKELQQNKKFQNFIKIRNSNLLARRRGIPECILLVTQRITKYPVLVERILQYTKERTEEHRDLCRALGLIKDMIAAVDLKVSEYEKNQKWLEILNKIENKTYTKLKNGHVFRKQALMSQERALLHDGLVYWKTATGRFKDILALLLTDVLLFLQEKDQKYIFAAVDQKPSVISLQKLIAREVANEERGMFLISASSAGPEMYEIHTSSKEERNNWMRRIQQAVESCPEEEGGRTSESDEERRKADARVAKIQQCQEILSNQDQQICTYLEEKLHIYAELGELSGFEDVHLEPHLLIKPDPGEPPQAASLLAAALREAESLQVAVKASKLADVSQPSEEGPGGAVLADTLSAQDAPASPTAFTEGTEGRGCWDVDPRLQGVVTDLAVSDAGEKVEYRSFSGSSQSEIIQAIQNLTRLLYSLQAALTIQDSHIEIHKLVLQQQESLAPSHSFRGGPLQDQEKSRYLEKHREELANIHKLQYQFQQEQRRWHRTCDQQQREQEAQESWLQARERECQSQEELLLRHRSELDHQLQEYQQNLERLREGQRMVERERQRMRDQQGLLGHCKHSRQRSLPAVFSPGSKEVTELNRAESLCHEKSFFLNDAFTHMSLNTSNKPNPSGAPWDAHPPGGSHLDLARTSDSQIEVKMDVSQPSDVNSELWTTGLGPQRPARQESIKDSCKNVADLNSFQTESPDPQDSNQRGPQPQTLITEAKLTPPMAAGHGGDAGDGAEENIVYL", "length": 1700 }, "evidence": [ { "id": "A0A8V0YEI5", "url": "https://omabrowser.org/oma/group/A0A8V0YEI5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P97433-1", "protein_name": "Rho guanine nucleotide exchange factor 28", "gene_name": "Arhgef28", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MELSCSEVPLYGQKTVYAKFGKNVYLPEDAEFYFVYGGSHQRHVVIADRVQDNVLQSSIPGHWLQETVTVSVCLCSEGYSPVTMGSGSVTYVDNMACRLARLLVTQADRLTACSHQTLLTPFALTVEALPALDEELVLALTQLELPLGWTVLGNSSLEVSLHRESLLHLAVRWALPKLFHFLLCLPGGVKALKLPNEEATTPLDLALQGGHSTLVEDITNFQGSHSPGFSRLRLNEEATLQFVHSSETLTLTVNHTAEHLLEADIKLFRKYFWDRAFLVKALEQEAKTEKATMPSGAAETEEEVRNLESGRSPSEEEEDAKSIKSQVDGPSEHEDQDRLPLDRSFDGLKKSKHVPASLAAGQLSDVLNGGDEVYANCMVIDQVGDLDINYINLEGLSTHTSPESGRSMLGPQACMHTLPPDTSPCGRPLIENSEGTLDAAASQSFVTPSSSRTSNLNLSFGLHGFEKEQSHLKKRSSSLDALVADSEGEGGSEPPICYAVGSQSSPRTGLPSGDELDSFETNTEPDCNISRTESLSLSSTLHSKESLLSGIRSRSYSCSSPKISSGKSRLVRDFTVCSTSEEQRSYSFQEPPGEKRIQEEEWDEYVIPAKSESEKYKVSRTFSFLMNRMTSPRNKSKMKNKDTKEKEKMNRHQFVPGTFSGVLQCSGCDKTLLGKESLQCANCKANTHKGCKDAVPPCTKKFQEKYNKNKPQSILGSSSVRDVPAPGLSLHPSSSMPIGLPAGRKEFAAQVHPLSRSVPGTTLESFRRAVTSLESEGDSWRSRSHSDELFQSMGSSPSTESFMMEDVVDSSLWIDLSSDAQEFEAESWSLVVDPSFCSRQEKDVIKRQDVIFELMQTEVHHIQTLLIMSEVFRKGMKEELQLDHSTVDKIFPCLDELLETHRHFFFSMKERRQESCAGSDRNFVINQIGDILVQQFSEENASKMKRIYGEFCSHHKEAMSLFKELQQNKKFQNFIKIRNSNLLARRRGIPECILLVTQRITKYPVLVERILQYTKERTEEHRDLCKALGLIKDMIAAVDLKVSEYEKNQKWLEILNKIENKTYTKLKNGHVFRKQALLSQERALLHDGLVYWKTATGRFKDILALLLTDVLLFLQEKDQKYIFAAVDQKPSVISLQKLIAREVANEERGMFLISASSAGPEMYEIHTNSKEERNNWMRRIQQAVESCPEEEGGRTSESDEERRKAEARVAKIQQCQEILSNQDQQICTYLEEKLHIYAELGELSGFEDVHLEPHLLIKPDPGEPPQAASLLAAALREAESLQVAVKASKMGDVSQSSEESPGGTVLMDTPSTQDVPASPTASLVTEGTEGRGCWDVDPGLQGVVTDLAVSDAGEKVEYRSFSGSSQSEIIQAIQNLTRLLYSLQAALTIQDSHIEIHKLVLQQRESLAPSHSFRGGPLQDQEKSRYLEKQREELANIHKLQHQFQQEQRRWHRTCDQQQREQEAQESWLQARERECQSQEELLLRHRSELDHQLQEYQQSLERLREGQRMVERERQKMRVQQGLLGHCKHSRQRSLPAVFSPGSKEVTELNRAESLCHENSFFINEAFGHMSLNTSNKPNPSGVPWDAHPLEGSHFDLARTSESPTELKIDISQPPDVNSELWTTGPGHQRPALQENSKESYKNVADLDSFQSESSSPQDSNQRGPQPQTLTTEAKLSLPMAAGHGGDAGDGAEENILYL", "length": 1700 }, "evidence": [ { "id": "A0A8V0YEI5", "url": "https://omabrowser.org/oma/group/A0A8V0YEI5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8N1W1-1", "protein_name": "Rho guanine nucleotide exchange factor 28", "gene_name": "ARHGEF28", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MELSCSEAPLYGQMMIYAKFDKNVYLPEDAEFYFTYDGSHQRHVMIAERIEDNVLQSSVPGHGLQETVTVSVCLCSEGYSPVTMGSGSVTYVDNMACRLARLLVTQANRLTACSHQTLLTPFALTAGALPALDEELVLALTHLELPLEWTVLGSSSLEVSSHRESLLHLAMRWGLAKLSQFFLCLPGGVQALALPNEEGATPLDLALREGHSKLVEDVTNFQGRWSPSFSRVQLSEEASLHYIHSSETLTLTLNHTAEHLLEADIKLFRKYFWDRAFLVKAFEPEARPEERTAMPSSGAETEEEIKNSVSSRSAAEKEDIKRVKSLVVQHNEHEDQHSLDLDRSFDILKKSKPPSTLLAAGRLSDMLNGGDEVYANCMVIDQVGDLDISYINIEGITATTSPESRGCTLWPQSSKHTLPTETSPSVYPLSENVEGTAHTEAQQSFMSPSSSCASNLNLSFGWHGFEKEQSHLKKRSSSLDALDADSEGEGHSEPSHICYTPGSQSSSRTGIPSGDELDSFETNTEPDFNISRAESLPLSSNLQSKESLLSGVRSRSYSCSSPKISLGKTRLVRELTVCSSSEEQRAYSLSEPPRENRIQEEEWDKYIIPAKSESEKYKVSRTFSFLMNRMTSPRNKSKTKSKDAKDKEKLNRHQFAPGTFSGVLQCLVCDKTLLGKESLQCSNCNANVHKGCKDAAPACTKKFQEKYNKNKPQTILGNSSFRDIPQPGLSLHPSSSVPVGLPTGRRETVGQVHPLSRSVPGTTLESFRRSATSLESESDHNSCRSRSHSDELLQSMGSSPSTESFIMEDVVDSSLWSDLSSDAQEFEAESWSLVVDPSFCNRQEKDVIKRQDVIFELMQTEMHHIQTLFIMSEIFRKGMKEELQLDHSTVDKIFPCLDELLEIHRHFFYSMKERRQESCAGSDRNFVIDRIGDILVQQFSEENASKMKKIYGEFCCHHKEAVNLFKELQQNKKFQNFIKLRNSNLLARRRGIPECILLVTQRITKYPVLVERILQYTKERTEEHKDLRKALCLIKDMIATVDLKVNEYEKNQKWLEILNKIENKTYTKLKNGHVFRKQALMSEERTLLYDGLVYWKTATGRFKDILALLLTDVLLFLQEKDQKYIFAAVDQKPSVISLQKLIAREVANEERGMFLISASSAGPEMYEIHTNSKEERNNWMRRIQQAVESCPEEKGGRTSESDEDKRKAEARVAKIQQCQEILTNQDQQICAYLEEKLHIYAELGELSGFEDVHLEPHLLIKPDPGEPPQAASLLAAALKEAESLQVAVKASQMGAVSQSCEDSCGDSVLADTLSSHDVPGSPTASLVTGGREGRGCSDVDPGIQGVVTDLAVSDAGEKVECRNFPGSSQSEIIQAIQNLTRLLYSLQAALTIQDSHIEIHRLVLQQQEGLSLGHSILRGGPLQDQKSRDADRQHEELANVHQLQHQLQQEQRRWLRRCEQQQRAQATRESWLQERERECQSQEELLLRSRGELDLQLQEYQHSLERLREGQRLVEREQARMRAQQSLLGHWKHGRQRSLPAVLLPGGPEVMELNRSESLCHENSFFINEALVQMSFNTFNKLNPSVIHQDATYPTTQSHSDLVRTSEHQVDLKVDPSQPSNVSHKLWTAAGSGHQILPFHESSKDSCKNDLDTSHTESPTPHDSNSHRPQLQAFITEAKLNLPTRTMTRQDGETGDGAKENIVYL", "length": 1705 }, "evidence": [ { "id": "A0A8V0YEI5", "url": "https://omabrowser.org/oma/group/A0A8V0YEI5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YEI5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEI5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YEI5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEI5" } ], "pmid": "" }, { "name": "guanyl-nucleotide exchange factor activity", "id": "GO:0005085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005085", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YEI5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEI5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "small GTPase-mediated signal transduction", "id": "GO:0007264", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007264", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YEI5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEI5" } ], "pmid": "" }, { "name": "regulation of Rho protein signal transduction", "id": "GO:0035023", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035023", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YEI5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEI5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1085, "end_pos": 1087, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1089, "end_pos": 1091, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1321, "end_pos": 1323, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1403, "end_pos": 1405, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1464, "end_pos": 1466, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1603, "end_pos": 1605, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1675, "end_pos": 1677, "annotation": "n_glycosylation_sequon" }, { "start_pos": 370, "end_pos": 372, "annotation": "n_glycosylation_sequon" }, { "start_pos": 435, "end_pos": 437, "annotation": "n_glycosylation_sequon" }, { "start_pos": 529, "end_pos": 531, "annotation": "n_glycosylation_sequon" }, { "start_pos": 683, "end_pos": 685, "annotation": "n_glycosylation_sequon" }, { "start_pos": 745, "end_pos": 747, "annotation": "n_glycosylation_sequon" }, { "start_pos": 94, "end_pos": 96, "annotation": "n_glycosylation_sequon" }, { "start_pos": 969, "end_pos": 971, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YEI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEI5" }, { "id": "PS50010", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50010" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "DH", "eco_id": "ECO_0000259", "start_pos": 874, "end_pos": 1070, "start_aa": "Lys", "end_aa": "Lys", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0YEI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEI5" }, { "id": "PS50003", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50003" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PH", "eco_id": "ECO_0000259", "start_pos": 1112, "end_pos": 1214, "start_aa": "Ile", "end_aa": "Glu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0YEI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEI5" }, { "id": "PS50081", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50081" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Phorbol-ester/DAG-type", "eco_id": "ECO_0000259", "start_pos": 678, "end_pos": 725, "start_aa": "Arg", "end_aa": "Cys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1085, "end_pos": 1087 }, { "start_pos": 1089, "end_pos": 1091 }, { "start_pos": 1321, "end_pos": 1323 }, { "start_pos": 1403, "end_pos": 1405 }, { "start_pos": 1464, "end_pos": 1466 }, { "start_pos": 1603, "end_pos": 1605 }, { "start_pos": 1675, "end_pos": 1677 }, { "start_pos": 370, "end_pos": 372 }, { "start_pos": 435, "end_pos": 437 }, { "start_pos": 529, "end_pos": 531 }, { "start_pos": 683, "end_pos": 685 }, { "start_pos": 745, "end_pos": 747 }, { "start_pos": 94, "end_pos": 96 }, { "start_pos": 969, "end_pos": 971 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YEJ1-1", "uniprot_ac": "A0A8V0YEJ1", "uniprot_id": "A0A8V0YEJ1_CHICK", "mass": { "chemical_mass": 40288.0, "monoisotopic_mass": 40288.0 }, "refseq": { "ac": "XP_004934616", "name": "immunoglobulin superfamily member 5 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004934616" }, "gene_names": [ { "name": "IGSF5", "type": "recommended", "evidence": [ { "id": "A0A8V0YEJ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEJ1" } ] }, { "name": "IGSF5", "type": "synonym", "evidence": [ { "id": "XP_004934616", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004934616" } ] } ], "protein_names": [ { "name": "Immunoglobulin superfamily member 5", "type": "recommended", "evidence": [ { "id": "A0A8V0YEJ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEJ1/entry#names_and_taxonomy" } ] }, { "name": "Junctional adhesion molecule 4", "type": "synonym", "evidence": [ { "id": "A0A8V0YEJ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEJ1/entry#names_and_taxonomy" } ] }, { "name": "immunoglobulin superfamily member 5 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_004934616", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004934616" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_004934616.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004934616", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004934616" } ] }, { "annotation": "Provides, together with MAGI1, an adhesion machinery at tight junctions, which may regulate the permeability of kidney glomerulus and small intestinal epithelial cells. Mediates calcium-independent homophilic cell adhesion. In testis, it may function as a cell adhesion molecule rather than a tight-junction protein. It may participate in the adhesion between spermatogonia-spermatogonia, spermatogonia-Sertoli cells, and Sertoli cells-Sertoli cells.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YEJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEJ1#function" }, { "database": "UniProtKB", "id": "ARBA00059983", "url": "https://www.uniprot.org/uniprotkb/ARBA00059983#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YEJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEJ1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "IGSF5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEJ1", "locus": { "chromosome": "1", "start_pos": 108210089, "end_pos": 108176160, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013504", "url": "https://www.ensembl.org/id/ENSGALG00010013504" } ] } } ], "crossref": [ { "id": "A0A8V0YEJ1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YEJ1", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00096", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00096", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "418524", "url": "https://www.ncbi.nlm.nih.gov/gene/418524", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013098", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013098", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:418524", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418524", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HSSYYFV", "url": "https://omabrowser.org/oma/group/HSSYYFV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YEJ1", "url": "https://www.orthodb.org/?gene=A0A8V0YEJ1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR44991", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR44991", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR44991:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR44991:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07679", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07679", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_004934616", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004934616", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YEJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEJ1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YEJ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEJ1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MERFQKFILLPFILAASLTGLGFCYSILNGPTNATVLAGSEARFNCTVANGWAILIWLLNTNPVLTVINSHGPIETSDRFTSQSYNNSQSFTSELIIHNTQLNDSGRIECSIQKIDGSSFAFLSVQVNGTLLIKNSTLIVKENTTVEIVCEALGWAPAPDITWMTNDSLIDKSRYVTQQSQGSNSLYNALSVLTLTPMDTEILTCLADIETLPSPQNATIAVIVGNSTLENNYSEDSTSTWVIVLAVVFSIVGFILLIILIWVVVRCCCLKKGSTYENEVRKISVKKKTDDRLGSRQRSGSENQGYVPEEPPYTGQIPTVVSLPPMSTKFTVPRPDLHTSSAPKGRPQRHTDYPINPKKIRNVTHV", "length": 366, "header": "tr|A0A8V0YEJ1-1|A0A8V0YEJ1_CHICK Isoform 1 of Immunoglobulin superfamily member 5 OS=Gallus gallus OX=9031 GN=IGSF5 PE=4 SV=1 CANONICAL=A0A8V0YEJ1-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YEJ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEJ1/entry#A0A8V0YEJ1-1", "sequence": { "sequence": "MERFQKFILLPFILAASLTGLGFCYSILNGPTNATVLAGSEARFNCTVANGWAILIWLLNTNPVLTVINSHGPIETSDRFTSQSYNNSQSFTSELIIHNTQLNDSGRIECSIQKIDGSSFAFLSVQVNGTLLIKNSTLIVKENTTVEIVCEALGWAPAPDITWMTNDSLIDKSRYVTQQSQGSNSLYNALSVLTLTPMDTEILTCLADIETLPSPQNATIAVIVGNSTLENNYSEDSTSTWVIVLAVVFSIVGFILLIILIWVVVRCCCLKKGSTYENEVRKISVKKKTDDRLGSRQRSGSENQGYVPEEPPYTGQIPTVVSLPPMSTKFTVPRPDLHTSSAPKGRPQRHTDYPINPKKIRNVTHV", "length": 366, "header": "tr|A0A8V0YEJ1-1|A0A8V0YEJ1_CHICK Isoform 1 of Immunoglobulin superfamily member 5 OS=Gallus gallus OX=9031 GN=IGSF5 PE=4 SV=1 CANONICAL=A0A8V0YEJ1-1" }, "locus": { "chromosome": "1", "start_pos": 108208757, "end_pos": 108179137, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032491.1", "url": "https://www.ensembl.org/id/ENSGALT00010032491.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019235.1", "url": "https://www.ensembl.org/id/ENSGALP00010019235.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:418524", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418524", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287A5B2-1", "protein_name": "Immunoglobulin superfamily member 5", "gene_name": "IGSF5", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEGSCRGVLAALVVLAGLAACGSGNEILEGPRNVTVVKGSEARFNCTISQGWKLIMWALKGTVVLSVTPTEPIITNDRFTSASYEEGGNFISEMIIHDVQLSDAGQVKCSLQNSDRDGSAFLSVQVMGALLIPGGSLVVLAEEPCNVTCRAWGWTPLPDISWEIGAPVSHSSYDSAPEPDDLQSAVSVLALTPLGSGSVTCVADMKGLPLQESVTVNLTVVQPPLGSVDKPGTSLPTWAIALLAVSLSLLSILIIVLIIIFCCCCASRREKEESSYQSQIRKSASVKTNTETFQTKSGKENYGYSSDEPRTTTSLPPKGSESSVPEQRGSRPPHQGLDHRQPGPASRPQVSFNVASPKKVRNATLV", "length": 366 }, "evidence": [ { "id": "A0A8V0YEJ1", "url": "https://omabrowser.org/oma/group/A0A8V0YEJ1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "E1BPQ9-1", "protein_name": "Immunoglobulin superfamily member 5", "gene_name": "IGSF5", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MEGAAERGVLAVLVVLAVLAACGSSSEIIEGPKNVTALKGSEARFNCTISQGWKLVMWALRGTVVLSMTPNETIITSDRFTSASYQEGGNFISEMIIHDVQLSDAGQVKCSLQNSNRDGAAFLSVQVMGQLLIPGGSLVVIEDKPCNVTCRALNWTLLPDLSWEIGVPVSHSSYYSIPEPEDLQSAVSVLALTPQGNGTVTCVAEMKGLDVRESVTVNLTVVQPPLDSIDKPGTSLPTWAIVLLAVSLSLLLILIIVLIIIFCCCVSRTEKEESSYQSQIRKSATVKTSKDTAGTKLKSANENYGYHSDESRTTQPASLHAKSSEAGVPEQCSSRQPHQESDHRQLGPANHPQVSFYVASPKKVRNVTLV", "length": 370 }, "evidence": [ { "id": "A0A8V0YEJ1", "url": "https://omabrowser.org/oma/group/A0A8V0YEJ1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q5VJ70-1", "protein_name": "Immunoglobulin superfamily member 5", "gene_name": "Igsf5", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEGSWRDVLAVLVILAQLTVSGSSYQIIEGPRNVTALKGSEARFNCTVTHGWKLIMWALNGIVELSLTSQKPIITSNRFTSASYNSTDSFISEMIIHNVQLNDSGPVQCSLQNSNVFGFAFLSVQVMGTLNIPSSNLIVTEGEPCNVTCYAVGWTPLPNISWELEVPVSHSSYYSFLEPGNSLRVLSVLDLTPLGNGTLTCVAEMKDLQASESLTVNLTVVQPPPDSIGGEGQALPTWAIILLAVAFSLLLILIIALIIIFCCCCVSRREKEESTYQNEIRKSANVRTGKADPETWLKSGKENYGYKSDEARAAQIASLPPKSGEVSLPEQRSSLPQQELDKHRPSPVTHPRVSFDIASPQKIRNVTIV", "length": 369 }, "evidence": [ { "id": "A0A8V0YEJ1", "url": "https://omabrowser.org/oma/group/A0A8V0YEJ1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q7TSN7-1", "protein_name": "Immunoglobulin superfamily member 5", "gene_name": "Igsf5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEGSWRDVLAVLVILAQLTASGSSYQIIEGPQNVTVLKDSEAHFNCTVTHGWKLLMWTLNQMVVLSLTTQGPIITNNRFTYASYNSTDSFISELIIHDVQPSDSGSVQCSLQNSHGFGSAFLSVQVMGTLNIPSNNLIVTEGEPCNVTCYAVGWTSLPDISWELEVPVSHSSYNSFLESGNFMRVLSVLDLTPLGNGTLTCVAELKDLQASKSLTVNLTVVQPPPDSIGEEGPALPTWAIILLAVAFSLLLILIIVLIIIFCCCCASRREKEESTYQNEIRKSANMRTNKADPETKLKGGKENYGYSSDEAKAAQTASLPPKSAEVSLPEKRSSSLPYQELNKHQPGPATHPRVSFDIASPQKVRNVTLV", "length": 370 }, "evidence": [ { "id": "A0A8V0YEJ1", "url": "https://omabrowser.org/oma/group/A0A8V0YEJ1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9NSI5-1", "protein_name": "Immunoglobulin superfamily member 5", "gene_name": "IGSF5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGQKERSTADTLPDLEEWKSAAGLRWWQTAVVDGSGSGNEVIEGPQNARVLKGSQARFNCTVSQGWKLIMWALSDMVVLSVRPMEPIITNDRFTSQRYDQGGNFTSEMIIHNVEPSDSGNIRCSLQNSRLHGSAYLTVQVMGELFIPSVNLVVAENEPCEVTCLPSHWTRLPDISWELGLLVSHSSYYFVPEPSDLQSAVSILALTPQSNGTLTCVATWKSLKARKSATVNLTVIRCPQDTGGGINIPGVLSSLPSLGFSLPTWGKVGLGLAGTMLLTPTCTLTIRCCCCRRRCCGCNCCCRCCFCCRRKRGFRIQFQKKSEKEKTNKETETESGNENSGYNSDEQKTTDTASLPPKSCESSDPEQRNSSCGPPHQRADQRPPRPASHPQASFNLASPEKVSNTTVV", "length": 407 }, "evidence": [ { "id": "A0A8V0YEJ1", "url": "https://omabrowser.org/oma/group/A0A8V0YEJ1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "bicellular tight junction", "id": "GO:0005923", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005923", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YEJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEJ1" } ], "pmid": "" }, { "name": "cell surface", "id": "GO:0009986", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009986", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YEJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEJ1" } ], "pmid": "" }, { "name": "apical plasma membrane", "id": "GO:0016324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016324", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YEJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEJ1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "cell-cell adhesion", "id": "GO:0098609", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098609", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YEJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEJ1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 103, "end_pos": 105, "annotation": "n_glycosylation_sequon" }, { "start_pos": 128, "end_pos": 130, "annotation": "n_glycosylation_sequon" }, { "start_pos": 135, "end_pos": 137, "annotation": 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Involved in nucleolar processing of pre-18S ribosomal RNA. Required for optimal pre-ribosomal RNA transcription by RNA polymerase I. Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YAX3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAX3#function" }, { "database": "UniProtKB", "id": "ARBA00045437", "url": "https://www.uniprot.org/uniprotkb/ARBA00045437#function" }, { "database": "UniProtKB", "id": "A0A8V0YEK0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEK0#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YEK0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEK0" } ], "common_name": "Chicken", 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"PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00400", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00400", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF09384", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09384", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-6791226", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6791226", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YAX3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAX3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YAX3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAX3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YEK0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEK0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YEK0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEK0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASYKPVVIPAVPKLGEKITQDTLYWRGYKTPVQIKEFGAINKIDFSPVPPYNYAVTASSRVHIYGRYSQEPIKTFSRFKDAAYCATYRDDGKLLVAGSEEGSIRLFDISGRAPLRQFDGHTKAVHVVGFLSDKYRIFSGGDDYSSSLWDIPSATEIVSYSEHSDYVRCGCASKLNGDVFITGSYDHTVKVFDARTKSSVMTIEHGHPVESVLLFPSGGLLVSAGRYVKVWDVLKGGQLLVSLKNHHKTVTCLCLNSSGQRLLSGSLDRHVKIYSTTSYKVVHSFNYATSILSLALSPEDETIIVGMTNGVLNVKHRKPEESKEKSQKKRQPAYRTYVKGRNYMPKQEDFFVSKPGRCIMRKYDKLLKSFQSSKALDAVLEPHIRLYTPEVTVAVMQELNRRGTLRSALAGRDEKQISLLLTFVTRRVIEPRFTPVLITVADMITDIYQPVVGQSALVDKQFLRLQEAIGREIDYQEELLEVLGMMDALFATLTEKRATYLEENKSNGLTKTLDQDISI", "length": 519, "header": "tr|A0A8V0YEK0-1|A0A8V0YEK0_CHICK Isoform 1 of U3 small nucleolar RNA-associated protein 15 homolog OS=Gallus gallus OX=9031 GN=UTP15 PE=4 SV=1 CANONICAL=A0A8V0YEK0-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YAX3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEK0/entry#A0A8V0YAX3-1", "sequence": { "sequence": "MASYKPVVIPAVPKLGEKITQDTLYWRGYKTPVQIKEFGAINKIDFSPVPPYNYAVTASSRVHIYGRYSQEPIKTFSRFKDAAYCATYRDDGKLLVAGSEEGSIRLFDISGRAPLRQFDGHTKAVHVVGFLSDKYRIFSGGDDYSSSLWDIPSATEIVSYSEHSDYVRCGCASKLNGDVFITGSYDHTVKVFDARTKSSVMTIEHGHPVESVLLFPSGGLLVSAGGRYVKVWDVLKGGQLLVSLKNHHKTVTCLCLNSSGQRLLSGSLDRHVKIYSTTSYKVVHSFNYATSILSLALSEDFFVSKPGRCIMRKYDKLLKSFQSSKALDAVLEPHIRLYTPEVTVAVMQELNRRGTLRSALAGRDEKQISLLLTFVTRRVIEPRFTPVLITVADMITDIYQPVVGQSALVDKQFLRLQEAIGREIDYQEELLEVLGMMDALFATLTEKRATYLEENKSNGLTKTLDQDISI", "length": 470, "header": "tr|A0A8V0YAX3-1|A0A8V0YAX3_CHICK Computationally mapped isoform of U3 small nucleolar RNA-associated protein 15 homolog OS=Gallus gallus OX=9031 GN=UTP15 PE=4 SV=1 CANONICAL=A0A8V0YEK0-1" }, "locus": { "chromosome": "Z", "start_pos": 25270024, "end_pos": 25260916, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028119.1", "url": "https://www.ensembl.org/id/ENSGALT00010028119.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016127.1", "url": "https://www.ensembl.org/id/ENSGALP00010016127.1" } ] } }, { "isoform_ac": "A0A8V0YEK0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEK0/entry#A0A8V0YEK0-1", "sequence": { "sequence": "MASYKPVVIPAVPKLGEKITQDTLYWRGYKTPVQIKEFGAINKIDFSPVPPYNYAVTASSRVHIYGRYSQEPIKTFSRFKDAAYCATYRDDGKLLVAGSEEGSIRLFDISGRAPLRQFDGHTKAVHVVGFLSDKYRIFSGGDDYSSSLWDIPSATEIVSYSEHSDYVRCGCASKLNGDVFITGSYDHTVKVFDARTKSSVMTIEHGHPVESVLLFPSGGLLVSAGRYVKVWDVLKGGQLLVSLKNHHKTVTCLCLNSSGQRLLSGSLDRHVKIYSTTSYKVVHSFNYATSILSLALSPEDETIIVGMTNGVLNVKHRKPEESKEKSQKKRQPAYRTYVKGRNYMPKQEDFFVSKPGRCIMRKYDKLLKSFQSSKALDAVLEPHIRLYTPEVTVAVMQELNRRGTLRSALAGRDEKQISLLLTFVTRRVIEPRFTPVLITVADMITDIYQPVVGQSALVDKQFLRLQEAIGREIDYQEELLEVLGMMDALFATLTEKRATYLEENKSNGLTKTLDQDISI", "length": 519, "header": "tr|A0A8V0YEK0-1|A0A8V0YEK0_CHICK Isoform 1 of U3 small nucleolar RNA-associated protein 15 homolog OS=Gallus gallus OX=9031 GN=UTP15 PE=4 SV=1 CANONICAL=A0A8V0YEK0-1" }, "locus": { "chromosome": "Z", "start_pos": 25270024, "end_pos": 25260916, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028099.1", "url": "https://www.ensembl.org/id/ENSGALT00010028099.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016118.1", "url": "https://www.ensembl.org/id/ENSGALP00010016118.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 57, "start_aa": "Thr", "end_pos": 57, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr57", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "R-GGA-6791226", "name": "", "url": 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"https://www.uniprot.org/uniprotkb/A0A8V0YEK0" } ], "pmid": "" }, { "name": "ribosomal small subunit biogenesis", "id": "GO:0042274", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042274", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YEK0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEK0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YEK0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEK0" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YEK0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEK0" } ], "pmid": "" }, { "name": "fibrillar center", "id": "GO:0001650", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001650", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YEK0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEK0" } ], "pmid": "" }, { "name": "small-subunit processome", "id": "GO:0032040", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032040", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YEK0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEK0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 256, "end_pos": 258, "annotation": "n_glycosylation_sequon" }, { "start_pos": 504, "end_pos": 506, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YEK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEK0" }, { "id": "PF09384", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09384" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "U3 small nucleolar RNA-associated protein 15 C-terminal", "eco_id": "ECO_0000259", "start_pos": 342, "end_pos": 489, "start_aa": "Asn", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 57 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 256, "end_pos": 258 }, { "start_pos": 504, "end_pos": 506 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { 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{ "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YEK9-1", "uniprot_ac": "A0A8V0YEK9", "uniprot_id": "A0A8V0YEK9_CHICK", "mass": { "chemical_mass": 54985.0, "monoisotopic_mass": 54985.0 }, "refseq": { "ac": "XP_040538545", "name": "prenylcysteine oxidase-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040538545" }, "gene_names": [ { "name": "PCYOX1L", "type": "recommended", "evidence": [ { "id": "A0A8V0YEK9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEK9" } ] }, { "name": "PCYOX1L", "type": "synonym", "evidence": [ { "id": "XP_040538545", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040538545" } ] } ], "protein_names": [ { "name": "prenylcysteine oxidase", "type": "recommended", "evidence": [ { "id": "A0A8V0YEK9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEK9/entry#names_and_taxonomy" } ] }, { "name": "1.8.3.5", "type": "synonym", "evidence": [ { "id": "A0A8V0YEK9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEK9/entry#names_and_taxonomy" } ] }, { "name": "prenylcysteine oxidase-like", "type": "synonym", "evidence": [ { "id": "XP_040538545", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040538545" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052585.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040538545", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040538545" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YEK9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEK9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PCYOX1L", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEK9", "locus": { "chromosome": "13", "start_pos": 8129213, "end_pos": 8131980, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010011764", "url": "https://www.ensembl.org/id/ENSGALG00010011764" } ] } } ], "crossref": [ { "id": "A0A8V0YEK9", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YEK9", "database": "AlphaFoldDB", "categories": [] }, { "id": "416200", "url": "https://www.ncbi.nlm.nih.gov/gene/416200", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR010795", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010795", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017046", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017046", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036188", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036188", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:416200", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416200", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "NMWAVEG", "url": "https://omabrowser.org/oma/group/NMWAVEG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YEK9", "url": "https://www.orthodb.org/?gene=A0A8V0YEK9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15944", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15944", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15944:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15944:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07156", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07156", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13450", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13450", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-114608", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-114608", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_040538545", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040538545", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "30231", "url": "https://www.rhea-db.org/rhea/30231", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "70407", "url": "https://www.rhea-db.org/rhea/70407", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YEK9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEK9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YEK9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEK9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAPPRAALLLPALAALLTVPVAARAPPRSIAVVGAGLGGSAVSYFLQQHFGPQVQLDVYERDGVGGRLATVTVNKQQYESRAASIHALSLHMQDFVKTLGLRQRRDVPGKSAVFSGEHFVLEETDWYLLNLFRLWWHYGISFLRLQMWVEEVMEKFMRIYKYQAHGYAFSSLEELLRSLGGEAFVNMTRRSVAEALLEVGVTQRFVDDVIAAVLRSSYGQSVLVPAFAGAMSLAGAQGSTWAVEGGNKLVCSGLLKLTKANVIHGRVTGVSLHSSEGRALYQVHYTSSEGQGSAFYDMVVVTTALHPSRSNFSFQNFEPPIDNFPGTFQPSVTSVVHGYLNSSYFGFPDPKLFPFASILTTDTPALFFNAMDNICPVNVSAAFRRKQPQEAAVWRVLSQQPLDRQQLKTLFRSYYSVQVTEWQSHPHYDSAKSLPPIVLHENLFYLSGVEWLASSMEMIAVAAKNVALLAYNRWHQDLEKIDQKDLMHKVKTEL", "length": 494, "header": "tr|A0A8V0YEK9-1|A0A8V0YEK9_CHICK Isoform 1 of prenylcysteine oxidase OS=Gallus gallus OX=9031 GN=PCYOX1L PE=1 SV=1 CANONICAL=A0A8V0YEK9-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YEK9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEK9/entry#A0A8V0YEK9-1", "sequence": { "sequence": "MAPPRAALLLPALAALLTVPVAARAPPRSIAVVGAGLGGSAVSYFLQQHFGPQVQLDVYERDGVGGRLATVTVNKQQYESRAASIHALSLHMQDFVKTLGLRQRRDVPGKSAVFSGEHFVLEETDWYLLNLFRLWWHYGISFLRLQMWVEEVMEKFMRIYKYQAHGYAFSSLEELLRSLGGEAFVNMTRRSVAEALLEVGVTQRFVDDVIAAVLRSSYGQSVLVPAFAGAMSLAGAQGSTWAVEGGNKLVCSGLLKLTKANVIHGRVTGVSLHSSEGRALYQVHYTSSEGQGSAFYDMVVVTTALHPSRSNFSFQNFEPPIDNFPGTFQPSVTSVVHGYLNSSYFGFPDPKLFPFASILTTDTPALFFNAMDNICPVNVSAAFRRKQPQEAAVWRVLSQQPLDRQQLKTLFRSYYSVQVTEWQSHPHYDSAKSLPPIVLHENLFYLSGVEWLASSMEMIAVAAKNVALLAYNRWHQDLEKIDQKDLMHKVKTEL", "length": 494, "header": "tr|A0A8V0YEK9-1|A0A8V0YEK9_CHICK Isoform 1 of prenylcysteine oxidase OS=Gallus gallus OX=9031 GN=PCYOX1L PE=1 SV=1 CANONICAL=A0A8V0YEK9-1" }, "locus": { "chromosome": "13", "start_pos": 8131968, "end_pos": 8129348, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028130.1", "url": "https://www.ensembl.org/id/ENSGALT00010028130.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016131.1", "url": "https://www.ensembl.org/id/ENSGALP00010016131.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "gga:416200", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416200", "resource": "KEGG Pathway" }, { "id": "R-GGA-114608", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-114608", "resource": "Reactome", "description": "Platelet degranulation" } ], "orthologs": [ { "uniprot_canonical_ac": "Q0P5H1-1", "protein_name": "Prenylcysteine oxidase 1-like", "gene_name": "PCYOX1L", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAHAARLLAALAALLAAAATGDARPSKIAVVGAGIGGSAVAHFLQQHFGPRVQIDVFEKGTVGGRLATISVNKQHYESGAASFHSLSLHMQGFVKQLGLRHRREVGGRSAIFNGENFVLEETDWYLLNLFRLWWHYGISFLRLQMWVEEVMEKFMRIYKYQAHGYAFSGVEELLYSLGESAFVNMTQRSVAESLLQVGVTQRFIDDVVSAVLRASYGQSAAMPAFAGAMSLAGAQGSLWSVEGGNKLVCSGLLKLTKANVIHATVTTVTLQPTEGKPLYRVRYENEAGTGSDNYDIVVIATPLHLDNSSTIAFEGFDPPIDVVQGSFQPTIVSLVHGYLNSSYFGFPDPKLFPFANILTTDFPTFFCALDNICPVNISASFRRKQPQEAAVWRVQSPQPLLRSQLKTLFRSYYSVQTAEWQAHPVHSPHTPLPRFTLHDQLFHLNALEWAASSVEVTAVAAKNVALLAFNRWYQDLDKIDQKDLMHKVKTEL", "length": 492 }, "evidence": [ { "id": "A0A8V0YEK9", "url": "https://omabrowser.org/oma/group/A0A8V0YEK9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q8C7K6-1", "protein_name": "Prenylcysteine oxidase 1-like", "gene_name": "Pcyox1l", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MARAAPLLAVLATVLTTAAAGGDAPPGKIAVIGAGIGGSAVAHFLQQHFGPRVQIVVYEKGTVGGRLATISVNKQNYESGAASFHSLSLHMQDFVKLLGLRQRREVVGRSAIFGGEHFVLEETDWYLLNLFRLWWYYGISFLRLQMWVEEVMEKFMRIYKYQAHGYAFSGVEELLYSLGEATFVNMTQRSVAESLLQVGVTQRFIDDVVSAVLRASYGQSASMPAFAGAMSLAGAQGNLWSVEGGNKLVCSGLLKLAKATVIHATVTSVTLHSTEGKALYQVAYESDKGNSSDFYDIVVIATPLHLDNSSNNNITFEGFTPPIEDIQGSFQPTVVSLVHGYLNSSYFGFPDPKLFPFANILTTDFPSFFCTLDNICPVNISASFRRKQPQEAAVWRVQSPKPLFRTELKTLFRSYYSVQTAEWQAHPLYGSRRTLPRFALHDQLFYLNALEWAASSVEVTAVAAKNVALLAYNRWYQDLDKIDQKDLIHKVKTEL", "length": 495 }, "evidence": [ { "id": "A0A8V0YEK9", "url": "https://omabrowser.org/oma/group/A0A8V0YEK9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8NBM8-1", "protein_name": "Prenylcysteine oxidase 1-like", "gene_name": "PCYOX1L", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MARAAPLLAALTALLAAAAAGGDAPPGKIAVVGAGIGGSAVAHFLQQHFGPRVQIDVYEKGTVGGRLATISVNKQHYESGAASFHSLSLHMQDFVKLLGLRHRREVVGRSAIFGGEHFMLEETDWYLLNLFRLWWHYGISFLRLQMWVEEVMEKFMRIYKYQAHGYAFSGVEELLYSLGESTFVNMTQHSVAESLLQVGVTQRFIDDVVSAVLRASYGQSAAMPAFAGAMSLAGAQGSLWSVEGGNKLVCSGLLKLTKANVIHATVTSVTLHSTEGKALYQVAYENEVGNSSDFYDIVVIATPLHLDNSSSNLTFAGFHPPIDDVQGSFQPTVVSLVHGYLNSSYFGFPDPKLFPFANILTTDFPSFFCTLDNICPVNISASFRRKQPQEAAVWRVQSPKPLFRTQLKTLFRSYYSVQTAEWQAHPLYGSRPTLPRFALHDQLFYLNALEWAASSVEVMAVAAKNVALLAYNRWYQDLDKIDQKDLMHKVKTEL", "length": 494 }, "evidence": [ { "id": "A0A8V0YEK9", "url": "https://omabrowser.org/oma/group/A0A8V0YEK9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "prenylcysteine oxidase activity", "id": "GO:0001735", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001735", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YEK9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEK9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "neutrophil-mediated killing of bacterium", "id": "GO:0070944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070944", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YEK9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEK9" } ], "pmid": "" }, { "name": "prenylcysteine catabolic process", "id": "GO:0030328", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030328", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YEK9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEK9" } ], "pmid": "" }, { "name": "prenylated protein catabolic process", "id": "GO:0030327", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030327", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YEK9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEK9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 186, "end_pos": 188, "annotation": "n_glycosylation_sequon" }, { "start_pos": 311, "end_pos": 313, "annotation": "n_glycosylation_sequon" }, { "start_pos": 341, "end_pos": 343, "annotation": "n_glycosylation_sequon" }, { "start_pos": 378, "end_pos": 380, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "30231", "name": "", "equation": "S-(2E,6E)-farnesyl-L-cysteine + O2 + H2O = (2E,6E)-farnesal + L-cysteine + H2O2", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0Z6I7-1", "A0A8V0YEK9-1" ], "evidence": [ { "id": "30231", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/30231" } ] }, { "id": "70407", "name": "", "equation": "[(2E,6E,10E)-geranylgeranyl]-L-cysteine + O2 + H2O = (2E,6E,10E)-geranylgeranial + L-cysteine + H2O2", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0Z6I7-1", "A0A8V0YEK9-1" ], "evidence": [ { "id": "70407", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/70407" } ] }, { "id": "R-GGA-481007", "name": "Exocytosis of platelet alpha granule contents", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0X7U8-1", "E1BWG1-1", "A0A8V0YEK9-1", "F1NWX6-1", "A0A8V0Y248-1" ], "evidence": [ { "id": "R-GGA-481007", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-481007" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A8V0X7U8", "gene_name": "ALDOA", "activity": [ { "ec_number": "4.1.2.13", "activity": "beta-D-fructose 1,6-bisphosphate = D-glyceraldehyde 3-phosphate + dihydroxyacetone phosphate.", "evidence": [ { "id": "A0A8V0X7U8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X7U8" } ] }, { "ec_number": "4.1.2.13", "activity": "", "evidence": [ { "id": "A0A8V0X7U8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X7U8" } ] } ] }, { "uniprot_ac": "A0A8V0Y248", "gene_name": "QSOX1", "activity": [ { "ec_number": "1.8.3.2", "activity": "2 R'C(R)SH + O2 = R'C(R)S-S(R)CR' + H2O2.", "evidence": [ { "id": "A0A8V0Y248", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y248" } ] }, { "ec_number": "1.8.3.2", "activity": "", "evidence": [ { "id": "A0A8V0Y248", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y248" } ] } ] }, { "uniprot_ac": "A0A8V0YEK9", "gene_name": "PCYOX1L", "activity": [ { "ec_number": "1.8.3.5", "activity": "an S-polyprenyl-L-cysteine + O2 + H2O = a polyprenal + L-cysteine + H2O2.", "evidence": [ { "id": "A0A8V0YEK9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEK9" } ] }, { "ec_number": "1.8.3.5", "activity": "", "evidence": [ { "id": "A0A8V0YEK9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEK9" } ] } ] }, { "uniprot_ac": "A0A8V0Z6I7", "gene_name": "PCYOX1", "activity": [ { "ec_number": "1.8.3.5", "activity": "an S-polyprenyl-L-cysteine + O2 + H2O = a polyprenal + L-cysteine + H2O2.", "evidence": [ { "id": "A0A8V0Z6I7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6I7" } ] }, { "ec_number": "1.8.3.5", "activity": "", "evidence": [ { "id": "A0A8V0Z6I7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6I7" } ] } ] }, { "uniprot_ac": "E1BWG1", "gene_name": "F13A1", "activity": [ { "ec_number": "2.3.2.13", "activity": "L-glutaminyl-[protein] + L-lysyl-[protein] = [protein]-L-lysyl-N(6)-5-L-glutamyl-[protein] + NH4(+).", "evidence": [ { "id": "E1BWG1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWG1" } ] }, { "ec_number": "2.3.2.13", "activity": "", "evidence": [ { "id": "E1BWG1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWG1" } ] } ] }, { "uniprot_ac": "F1NWX6", "gene_name": "PLG", "activity": [ { "ec_number": "3.4.21.7", "activity": "Preferential cleavage: Lys-|-Xaa > Arg-|-Xaa, higher selectivity than trypsin. Converts fibrin into soluble products.", "evidence": [ { "id": "F1NWX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NWX6" } ] }, { "ec_number": "3.4.21.7", "activity": "", "evidence": [ { "id": "F1NWX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NWX6" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YEK9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEK9" }, { "id": "PF07156", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07156" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Prenylcysteine lyase", "eco_id": "ECO_0000259", "start_pos": 121, "end_pos": 483, "start_aa": "Leu", "end_aa": "Gln", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "1.8.3.5", "ec_name": "an S-polyprenyl-L-cysteine + O2 + H2O = a polyprenal + L-cysteine 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"protein_names": [ { "name": "CCHC-type domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A8V0YEL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEL8/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YEL8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEL8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEL8", "locus": {} } ], "crossref": [ { "id": "A0A8V0YEL8", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YEL8", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR001878", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001878", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036875", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036875", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PF00098", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00098", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YEL8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEL8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YEL8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEL8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSSAWLRCFRCGGAQHVKRECPSKALGPGKPVRAQESCFSCGKPGHCVRECRSGSGNGRRSTFLGATTQM", "length": 70, "header": "tr|A0A8V0YEL8-1|A0A8V0YEL8_CHICK Isoform 1 of CCHC-type domain-containing protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0YEL8-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YEL8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEL8/entry#A0A8V0YEL8-1", "sequence": { "sequence": "MSSAWLRCFRCGGAQHVKRECPSKALGPGKPVRAQESCFSCGKPGHCVRECRSGSGNGRRSTFLGATTQM", "length": 70, "header": "tr|A0A8V0YEL8-1|A0A8V0YEL8_CHICK Isoform 1 of CCHC-type domain-containing protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0YEL8-1" }, "locus": { "chromosome": "W", "start_pos": 9045480, "end_pos": 9045002, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032520.1", "url": "https://www.ensembl.org/id/ENSGALT00010032520.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019260.1", "url": "https://www.ensembl.org/id/ENSGALP00010019260.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YEL8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEL8" } ], "pmid": "" }, { "name": "nucleic acid binding", "id": "GO:0003676", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003676", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YEL8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEL8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YEL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEL8" }, { "id": "PS50158", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50158" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CCHC-type", "eco_id": "ECO_0000259", "start_pos": 7, "end_pos": 23, "start_aa": "Arg", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YEM5-1", "uniprot_ac": "A0A8V0YEM5", "uniprot_id": "A0A8V0YEM5_CHICK", "mass": { "chemical_mass": 96532.0, "monoisotopic_mass": 96532.0 }, "refseq": { "ac": "NP_001305917", "name": "interleukin-17 receptor A precursor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001305917" }, "gene_names": [ { "name": "IL17RA", "type": "recommended", "evidence": [ { "id": "A0A8V0YEM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEM5" } ] }, { "name": "IL17RA", "type": "synonym", "evidence": [ { "id": "NP_001305917", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001305917" } ] }, { "name": "IL17R", "type": "synonym", "evidence": [ { "id": "NP_001305917", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001305917" } ] } ], "protein_names": [ { "name": "Interleukin 17 receptor A", "type": "synonym", "evidence": [ { "id": "A0A8V0YEM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEM5/entry#names_and_taxonomy" } ] }, { "name": "interleukin-17 receptor A precursor", "type": "synonym", "evidence": [ { "id": "NP_001305917", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001305917" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: KF743557.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000012.1. On Sep 23, 2021 this sequence version replaced NP_001305917.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001305917", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001305917" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YEM5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEM5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "IL17RA", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEM5", "locus": { "chromosome": "1", "start_pos": 61687848, "end_pos": 61665762, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010011776", "url": "https://www.ensembl.org/id/ENSGALG00010011776" } ] } } ], "crossref": [ { "id": "A0A8V0YEM5", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YEM5", "database": "AlphaFoldDB", "categories": [] }, { "id": "418158", "url": "https://www.ncbi.nlm.nih.gov/gene/418158", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013568", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013568", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032356", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032356", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038683", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038683", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039465", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039465", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043046", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043046", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:418158", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418158", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0Y676", "url": "https://www.orthodb.org/?gene=A0A8V0Y676", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YEM0", "url": "https://www.orthodb.org/?gene=A0A8V0YEM0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YEM5", "url": "https://www.orthodb.org/?gene=A0A8V0YEM5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15583", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15583", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15583:SF13", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15583:SF13", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF08357", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08357", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16556", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16556", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16578", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16578", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001305917", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001305917", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Y676", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y676", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y676-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y676-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YEM0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEM0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YEM0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEM0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YEM5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEM5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YEM5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEM5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAGAGRPGLSPPLLFLLVLPVPPAAAALRLLLGAAPPFTCSQPDLNCLVGNSTCIERSWLQNQTWTPSAPSSLDVFSDVFRQTDGELLPVLRIEWKVATDASIRYLRGAELAVMQVSSNQQICAQFEFQNNLPLQVRPDGGRWNFTFNRFEVEPGQTYQVTVYHLPKLSVNGDYNCKSVSLTMPDCTDTLMKRTTPCIKTGSLWEPKIQARSLDDITLLVSFNPWREPTRYQIHVTSFLNERKCKMITRDVTEGELQPQANVTIKMEKNLRACCTYKVQIQPFFAICGTDCLRHSTFIPCSPAPSVGPSDDMMIWVYWCITGICVLLVGSVIAGVICMTKKRGGHGRGKCSHYDLQTVPPTDLPLPPLKPRKVWIVYSADHLLYVDVVLKFAEFLMTVCGTAVALDLLEDHQISEFGPLPWLTRQKKEMEELSSKIIILCSRGTQAKWQAMLGSAPVCLKQDQQKPTGDLFTPALNLILPDFKKPACFGMYIVCYFDGISSEKDIPDLFNVTSRYQLMDKFEDIYFRIQDLEKFEPGRIHRIQEITAENYIDTPSGRKLKEAIQKFRNWQTEHPDWFEAESISLDNEEELQSLNRESQVDSLLSEPGGIVKHQLHLREPDPNCCYVINLHIREGESRGCKLQPQLNLCGDPASQTLIDPMDEAAPVQVVEPVSFMEDKNILGHHVLSNEDCMEGVPLLETSFPMRNNIILHDDCDVSAIDEQSPANLSGELRHHLNGLMYSLYQQSVIPSDPCFCQEEADKEHQLIFEDQCKDQRQSVQSDQGYISRCSPLPPDDPVEEEEEDQENQVVCHELSPEVLNSLKSLQQQLFFQDIQRSSESGYPAELMNMSPSPEDC", "length": 855, "header": "tr|A0A8V0YEM5-1|A0A8V0YEM5_CHICK Isoform 1 of Interleukin 17 receptor A OS=Gallus gallus OX=9031 GN=IL17RA PE=4 SV=1 CANONICAL=A0A8V0YEM5-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Y676-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEM5/entry#A0A8V0Y676-1", "sequence": { "sequence": "MGSPSCWSQRGTCIERSWLQNQTWTPSAPSSLDVFSDVFRQTDGELLPVLRIEWKVATDASIRYLRGAELAVMQVSSNQQICAQFEFQNNLPLQVRPDGGRWNFTFNRFEVEPGQTYQVTVYHLPKLSVNGDYNCKSVSLTMPDCTDTLMKRTTPCIKTGSLWEPKIQARSLDDITLLVSFNPWREPTRYQIHVTSFLNERKCKMITRDVTEGELQPQANVTIKMEKNLRACCTYKVQIQPFFAICGTDCLRHSTFIPCSPAPSVGPSDDMMIWVYWCITGICVLLVGSVIAGVICMTKKRGGHGRGKCSHYDLQTVPPTDLPLPPLKPRKVWIVYSADHLLYVDVVLKFAEFLMTVCGTAVALDLLEDHQISEFGPLPWLTRQKKEMEELSSKIIILCSRGTQAKWQAMLGSAPVCLKQDQQKPTGDLFTPALNLILPDFKKPACFGMYIVCYFDGISSEKDIPDLFNVTSRYQLMDKFEDIYFRIQDLEKFEPGRIHRIQEITAENYIDTPSGRKLKEAIQKFRNWQTEHPDWFEAESISLDNEEELQSLNRESQVDSLLSEPGGIVKHQLHLREPDPNCCYVINLHIREGESRGCKLQPQLNLCGDPASQTLIDPMDEAAPVQVVEPVSFMEDKNILGHHVLSNEDCMEGVPLLETSFPMRNNIILHDDCDVSAIDEQSPANLSGELRHHLNGLMYSLYQQSVIPSDPCFCQEEADKEHQLIFEDQCKDQRQSVQSDQGYISRCSPLPPDDPVEEEEEDQENQVVCHELSPEVLNSLKSLQQQLFFQDIQRSSESGYPAELMNMSPSPEDC", "length": 814, "header": "tr|A0A8V0Y676-1|A0A8V0Y676_CHICK Computationally mapped isoform of Interleukin 17 receptor A OS=Gallus gallus OX=9031 GN=IL17RA PE=4 SV=1 CANONICAL=A0A8V0YEM5-1" }, "locus": { "chromosome": "1", "start_pos": 61685028, "end_pos": 61672193, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028153.1", "url": "https://www.ensembl.org/id/ENSGALT00010028153.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016143.1", "url": "https://www.ensembl.org/id/ENSGALP00010016143.1" } ] } }, { "isoform_ac": "A0A8V0YEM0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEM5/entry#A0A8V0YEM0-1", "sequence": { "sequence": 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CANONICAL=A0A8V0YEM5-1" }, "locus": { "chromosome": "1", "start_pos": 61685028, "end_pos": 61668389, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028149.1", "url": "https://www.ensembl.org/id/ENSGALT00010028149.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016141.1", "url": "https://www.ensembl.org/id/ENSGALP00010016141.1" } ] } }, { "isoform_ac": "A0A8V0YEM5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEM5/entry#A0A8V0YEM5-1", "sequence": { "sequence": "MAGAGRPGLSPPLLFLLVLPVPPAAAALRLLLGAAPPFTCSQPDLNCLVGNSTCIERSWLQNQTWTPSAPSSLDVFSDVFRQTDGELLPVLRIEWKVATDASIRYLRGAELAVMQVSSNQQICAQFEFQNNLPLQVRPDGGRWNFTFNRFEVEPGQTYQVTVYHLPKLSVNGDYNCKSVSLTMPDCTDTLMKRTTPCIKTGSLWEPKIQARSLDDITLLVSFNPWREPTRYQIHVTSFLNERKCKMITRDVTEGELQPQANVTIKMEKNLRACCTYKVQIQPFFAICGTDCLRHSTFIPCSPAPSVGPSDDMMIWVYWCITGICVLLVGSVIAGVICMTKKRGGHGRGKCSHYDLQTVPPTDLPLPPLKPRKVWIVYSADHLLYVDVVLKFAEFLMTVCGTAVALDLLEDHQISEFGPLPWLTRQKKEMEELSSKIIILCSRGTQAKWQAMLGSAPVCLKQDQQKPTGDLFTPALNLILPDFKKPACFGMYIVCYFDGISSEKDIPDLFNVTSRYQLMDKFEDIYFRIQDLEKFEPGRIHRIQEITAENYIDTPSGRKLKEAIQKFRNWQTEHPDWFEAESISLDNEEELQSLNRESQVDSLLSEPGGIVKHQLHLREPDPNCCYVINLHIREGESRGCKLQPQLNLCGDPASQTLIDPMDEAAPVQVVEPVSFMEDKNILGHHVLSNEDCMEGVPLLETSFPMRNNIILHDDCDVSAIDEQSPANLSGELRHHLNGLMYSLYQQSVIPSDPCFCQEEADKEHQLIFEDQCKDQRQSVQSDQGYISRCSPLPPDDPVEEEEEDQENQVVCHELSPEVLNSLKSLQQQLFFQDIQRSSESGYPAELMNMSPSPEDC", "length": 855, "header": "tr|A0A8V0YEM5-1|A0A8V0YEM5_CHICK Isoform 1 of Interleukin 17 receptor A OS=Gallus gallus OX=9031 GN=IL17RA PE=4 SV=1 CANONICAL=A0A8V0YEM5-1" }, "locus": { "chromosome": "1", "start_pos": 61685028, "end_pos": 61665801, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028157.1", "url": "https://www.ensembl.org/id/ENSGALT00010028157.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016146.1", "url": "https://www.ensembl.org/id/ENSGALP00010016146.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:418158", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418158", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YEM5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEM5" } ], "pmid": "" } ] }, { "name": 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"https://www.ebi.ac.uk/QuickGO/term/GO:0032755", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YEM5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEM5" } ], "pmid": "" }, { "name": "response to virus", "id": "GO:0009615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009615", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YEM5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEM5" } ], "pmid": "" }, { "name": "positive regulation of inflammatory response", "id": "GO:0050729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050729", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YEM5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEM5" } ], "pmid": "" }, { "name": "protein catabolic process", "id": "GO:0030163", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030163", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YEM5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEM5" } ], "pmid": "" }, { "name": "granulocyte chemotaxis", "id": "GO:0071621", 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"https://www.uniprot.org/uniprotkb/A0A8V0YEM5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 144, "end_pos": 146, "annotation": "n_glycosylation_sequon" }, { "start_pos": 261, "end_pos": 263, "annotation": "n_glycosylation_sequon" }, { "start_pos": 510, "end_pos": 512, "annotation": "n_glycosylation_sequon" }, { "start_pos": 51, "end_pos": 53, "annotation": "n_glycosylation_sequon" }, { "start_pos": 62, "end_pos": 64, "annotation": "n_glycosylation_sequon" }, { "start_pos": 726, "end_pos": 728, "annotation": "n_glycosylation_sequon" }, { "start_pos": 847, "end_pos": 849, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YEM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEM5" }, { "id": "PS51534", "database": 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"GFKMLFPYLICYGLCPIEGTTNEPGGKHPESSEAQPRTELCHWPCQCPPVPTCSPGVSLLKDGCGCCKACAKQAGEVCNEVDICDPHKGLYCDYSQDEPRYETGVCAYLVAVGCELNGIYYLNGQNFQPNPLYKCLCISGAIGCTPIFTPKLAASPCSSGMGRKKNGQTVCGPGQNKQLQSVNYRLMSGVP", "length": 191, "header": "tr|A0A8V0YEM6-1|A0A8V0YEM6_CHICK Isoform 1 of Cellular communication network factor 6 OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0YEM6-1" }, "locus": { "chromosome": "3", "start_pos": 65521347, "end_pos": 65520192, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032535.1", "url": "https://www.ensembl.org/id/ENSGALT00010032535.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019273.1", "url": "https://www.ensembl.org/id/ENSGALP00010019273.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YEM6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEM6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YEM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEM6" }, { "id": "PS51323", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51323" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "IGFBP N-terminal", "eco_id": "ECO_0000259", "start_pos": 37, "end_pos": 109, "start_aa": "Arg", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YEM7-1", "uniprot_ac": "A0A8V0YEM7", "uniprot_id": "A0A8V0YEM7_CHICK", "mass": { "chemical_mass": 51031.0, "monoisotopic_mass": 51031.0 }, "refseq": { "ac": "NP_001186486", "name": "ribitol-5-phosphate xylosyltransferase 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186486" }, "gene_names": [ { "name": "TMEM5", "type": "recommended", "evidence": [ { "id": "A0A8V0YEM7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEM7" } ] }, { "name": "RXYLT1", "type": "synonym", "evidence": [ { "id": "NP_001186486", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186486" } ] }, { "name": "TMEM5", "type": "synonym", "evidence": [ { "id": "NP_001186486", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186486" } ] } ], "protein_names": [ { "name": "Transmembrane protein 5", "type": "synonym", "evidence": [ { "id": "A0A8V0YEM7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEM7/entry#names_and_taxonomy" } ] }, { "name": "ribitol xylosyltransferase 1", "type": "synonym", "evidence": [ { "id": "NP_001186486", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186486" } ] }, { "name": "ribitol-5-phosphate xylosyltransferase 1", "type": "synonym", "evidence": [ { "id": "NP_001186486", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186486" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: BX932028.2, HAEL01006650.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000012.1. On Dec 3, 2021 this sequence version replaced NP_001186486.1. Sequence Note: This RefSeq record was created from transcripts from different strains and genomic sequence data because no single transcript from the same strain was available for the full length of the gene. The extent of this transcript is supported by transcript alignments and orthologous data.", "evidence": [ { "database": "RefSeq", "id": "NP_001186486", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186486" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YEM7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEM7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TMEM5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEM7", "locus": { "chromosome": "1", "start_pos": 33534673, "end_pos": 33522572, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012198", "url": "https://www.ensembl.org/id/ENSGALG00010012198" } ] } } ], "crossref": [ { "id": "A0A8V0YEM7", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YEM7", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd21099", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd21099", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "417820", "url": "https://www.ncbi.nlm.nih.gov/gene/417820", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR055286", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055286", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057538", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057538", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057539", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057539", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:417820", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417820", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "IVGRTHY", "url": "https://omabrowser.org/oma/group/IVGRTHY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YEM7", "url": "https://www.orthodb.org/?gene=A0A8V0YEM7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YGS4", "url": "https://www.orthodb.org/?gene=A0A8V0YGS4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15576", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15576", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15576:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15576:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF24785", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24785", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24786", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24786", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-9939291", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9939291", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001186486", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186486", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YEM7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEM7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YEM7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEM7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YGS4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGS4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YGS4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGS4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRGARKRLCSALLVAYGLFSLYAAYTVFLRPRRPAASRPPHRDRHGPRGIDHVSLGNEEWNPWEADEKSEQVAAQQRYENILKLVQNARSQLEQTSLRVQIWGKAAIGLYLWQHIFGGHLEPADVTAQWREGSQKAGKTHFSFITGPSVVPGYFSVEAENVVLVLNGREKAKIAYATQWLHYAQTLLQTHKIQHVAVVLLGNEQCNNEWIQPYLKRHGGFVNLLFVTYDYALVNEEDIFQWPLGVATYRNFPVVEPSWSMLHDARSYLCNFLGTVYKNSSRETLMEILKQDGFDKLCWIAAREQWQPQETNESLKNYQDALLQSDLTLCPVGINTECYRIYEACSYGSVPVIEDVMTRGDCRNSSMYHSAPLQLLKTMGAPFIFIKNWKELPAVLEKEKKMSLQEKIQRRKKLIEWYQNFKAWMRQKFISTLENSFLPSDKG", "length": 442, "header": "tr|A0A8V0YEM7-1|A0A8V0YEM7_CHICK Isoform 1 of Transmembrane protein 5 OS=Gallus gallus OX=9031 GN=TMEM5 PE=4 SV=1 CANONICAL=A0A8V0YEM7-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YEM7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEM7/entry#A0A8V0YEM7-1", "sequence": { "sequence": "MRGARKRLCSALLVAYGLFSLYAAYTVFLRPRRPAASRPPHRDRHGPRGIDHVSLGNEEWNPWEADEKSEQVAAQQRYENILKLVQNARSQLEQTSLRVQIWGKAAIGLYLWQHIFGGHLEPADVTAQWREGSQKAGKTHFSFITGPSVVPGYFSVEAENVVLVLNGREKAKIAYATQWLHYAQTLLQTHKIQHVAVVLLGNEQCNNEWIQPYLKRHGGFVNLLFVTYDYALVNEEDIFQWPLGVATYRNFPVVEPSWSMLHDARSYLCNFLGTVYKNSSRETLMEILKQDGFDKLCWIAAREQWQPQETNESLKNYQDALLQSDLTLCPVGINTECYRIYEACSYGSVPVIEDVMTRGDCRNSSMYHSAPLQLLKTMGAPFIFIKNWKELPAVLEKEKKMSLQEKIQRRKKLIEWYQNFKAWMRQKFISTLENSFLPSDKG", "length": 442, "header": "tr|A0A8V0YEM7-1|A0A8V0YEM7_CHICK Isoform 1 of Transmembrane protein 5 OS=Gallus gallus OX=9031 GN=TMEM5 PE=4 SV=1 CANONICAL=A0A8V0YEM7-1" }, "locus": { "chromosome": "1", "start_pos": 33533475, "end_pos": 33522648, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029250.1", "url": "https://www.ensembl.org/id/ENSGALT00010029250.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016970.1", "url": "https://www.ensembl.org/id/ENSGALP00010016970.1" } ] } }, { "isoform_ac": "A0A8V0YGS4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEM7/entry#A0A8V0YGS4-1", "sequence": { "sequence": "MSFITGPSVVPGYFSVEAENVVLVLNGREKAKIAYATQWLHYAQTLLQTHKIQHVAVVLLGNEQCNNEWIQPYLKRHGGFVNLLFVTYDYALVNEEDIFQWPLGVATYRNFPVVEPSWSMLHDARSYLCNFLGTVYKNSSRETLMEILKQDGFDKLCWIAAREQWQPQETNESLKNYQDALLQSDLTLCPVGINTECYRIYEACSYGSVPVIEDVMTRGDCRNSSMYHSAPLQLLKTMGAPFIFIKNWKELPAVLEKEKKMSLQEKIQRRKKLIEWYQNFKAWMRQKFISTLENSFLPSDKG", "length": 302, "header": "tr|A0A8V0YGS4-1|A0A8V0YGS4_CHICK Computationally mapped isoform of Transmembrane protein 5 OS=Gallus gallus OX=9031 GN=TMEM5 PE=4 SV=1 CANONICAL=A0A8V0YEM7-1" }, "locus": { "chromosome": "1", "start_pos": 33533475, "end_pos": 33527809, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029245.1", "url": "https://www.ensembl.org/id/ENSGALT00010029245.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016966.1", "url": "https://www.ensembl.org/id/ENSGALP00010016966.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:417820", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417820", "resource": "KEGG Pathway" }, { "id": "R-GGA-9939291", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9939291", "resource": "Reactome", "description": "Matriglycan biosynthesis on DAG1" } ], "orthologs": [ { "uniprot_canonical_ac": "F1MKC5-1", "protein_name": "Ribitol xylosyltransferase 1", "gene_name": "RXYLT1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MRLTRKRLCSIFIAVYCLFSLYAAYHVFFGRRRRTPDVPLRGLRKGVVPVRERRSREQSTLRSEEWNPWEEDEKKEQQHRLKTSLQIVNKSTKEKKLFHVQIWGKAAIGLYLWEHIFEGLLEPTDVTAQWREGNSVVGRTHYSFITGPAVVPGYFSVDVNNVVLVLNGREKAKVFYATQWLLYAQNLVQTQKLQHLAVVLLGNEHCNNEWINQFLKRNGGSVERLFIIYDSPWINDMDVFQWPLGVATYRNFPVVEVNWSMLHNERPYLCNFVGTVYENSSRQALMKILKQDGNDKLCWVSAREQWQPQETNESLKNYQDALLQSDLTLCPAGVNTECYRIYEACSYGSVPVVEDVMTAGSCGNSSVYLNAPLQLLKSMNAPFIFIKNWKELPAILEKEKTINLEEKIQRRKRLLHWYQHFKTELKMRFTNILESSFLKNNKN", "length": 443 }, "evidence": [ { "id": "A0A8V0YEM7", "url": "https://omabrowser.org/oma/group/A0A8V0YEM7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1SKB9-1", "protein_name": "Ribitol xylosyltransferase 1", "gene_name": "RXYLT1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRLTRKRLCSFLIALYCLFSLYAAYHVFFGGRRRTPAPSLRGLRKGAVPARERRGRAEQSTLRSEEWNPWEGDEKNEQQQRLKTSLQILNKSTKGKTDFHVQIWGKAAIGLYLWEHIFEGLLEPTDVTAQWREGNSVVGRTHYSFITGPAVVPGYFSVDVNNVILILNGREKAKVFYATQWLLYAQNLVQTQKLQHLSVVLLGNEHCNNEWINQFLKRNGGSVELLFVVYDSPWINDMDVFQWPLGVATYRNFPVVEASWSMLHNERPYLCNFFGTVYENSSRQVLMNILKQDGNDKLCWVSAREQWQPQETNESLKNYQDALLQSDLTLCPAGVNTECYRIYEACSYGSIPVVEDVMTSGCYGNTSVYYNAPLQLLKSMNAPFIFIKNWKELPAILEKEKTIILQEKIQRRKRLLHWYQHFKTELKMRFTNILENSFLRNNKG", "length": 444 }, "evidence": [ { "id": "A0A8V0YEM7", "url": "https://omabrowser.org/oma/group/A0A8V0YEM7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q8VDX6-1", "protein_name": "Ribitol-5-phosphate xylosyltransferase 1", "gene_name": "Rxylt1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRLTRTRLCSLLVALYCLFSIYAAYHVFFGRRRRPLGTTSRNSRKAAAAQAKERRGREQSALESEEWNPWEGDEKNEQRHRVKTNLQILNKSTKEKIEHRVQIWGKAAIGLYLWEHIFEGTLDPADVTAQWREGQSVVGRTHYSFITGPAVVPGYFSIDVDNVVLVLNGREKAKIFHATQWLIYAQNLMKTQKLQHLAVVLLGNEHCENDWIMQFLKRNGGFVDLLFITYDSPWINGADILQWPLGVATYRQFPVVEASWTMLHDERPYICNFLGTAYENSSRQALMNILKQDGNDKLCWVSAREQWQPQETNESLKNYQDALLHSDLTLCPVGVNTECYRIYEACSFGSIPVVEDVMTAGHCGNTTSQHSAPLQLLKAMGAPFIFIKNWKELPAILEKEKTISLQEKIQRRKVLLHWYQHFKTELKWKFTKILESSFFINNKV", "length": 444 }, "evidence": [ { "id": "A0A8V0YEM7", "url": "https://omabrowser.org/oma/group/A0A8V0YEM7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9Y2B1-1", "protein_name": "Ribitol-5-phosphate xylosyltransferase 1", "gene_name": "RXYLT1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRLTRKRLCSFLIALYCLFSLYAAYHVFFGRRRQAPAGSPRGLRKGAAPARERRGREQSTLESEEWNPWEGDEKNEQQHRFKTSLQILDKSTKGKTDLSVQIWGKAAIGLYLWEHIFEGLLDPSDVTAQWREGKSIVGRTQYSFITGPAVIPGYFSVDVNNVVLILNGREKAKIFYATQWLLYAQNLVQIQKLQHLAVVLLGNEHCDNEWINPFLKRNGGFVELLFIIYDSPWINDVDVFQWPLGVATYRNFPVVEASWSMLHDERPYLCNFLGTIYENSSRQALMNILKKDGNDKLCWVSAREHWQPQETNESLKNYQDALLQSDLTLCPVGVNTECYRIYEACSYGSIPVVEDVMTAGNCGNTSVHHGAPLQLLKSMGAPFIFIKNWKELPAVLEKEKTIILQEKIERRKMLLQWYQHFKTELKMKFTNILESSFLMNNKS", "length": 443 }, "evidence": [ { "id": "A0A8V0YEM7", "url": "https://omabrowser.org/oma/group/A0A8V0YEM7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YEM7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEM7" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YEM7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEM7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "protein O-linked glycosylation via mannose", "id": "GO:0035269", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035269", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YEM7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEM7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "ribitol beta-1,4-xylosyltransferase activity", "id": "GO:0120053", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120053", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YEM7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEM7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 278, "end_pos": 280, "annotation": "n_glycosylation_sequon" }, { "start_pos": 311, "end_pos": 313, "annotation": "n_glycosylation_sequon" }, { "start_pos": 363, "end_pos": 365, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YEM7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEM7" }, { "id": "PF24785", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24785" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RXYLT1 C-terminal", "eco_id": "ECO_0000259", "start_pos": 248, "end_pos": 437, "start_aa": "Tyr", "end_aa": "Leu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0YEM7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEM7" }, { "id": "PF24786", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24786" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RXYLT1 N-terminal", "eco_id": "ECO_0000259", "start_pos": 99, "end_pos": 242, "start_aa": "Val", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 278, "end_pos": 280 }, { "start_pos": 311, "end_pos": 313 }, { "start_pos": 363, "end_pos": 365 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { 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"n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YEP4-1", "uniprot_ac": "A0A8V0YEP4", "uniprot_id": "A0A8V0YEP4_CHICK", "mass": { "chemical_mass": 47973.0, "monoisotopic_mass": 47973.0 }, "refseq": { "ac": "XP_004938006", "name": "haloacid dehalogenase-like hydrolase domain-containing 5 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004938006" }, "gene_names": [ { "name": "HDHD5", "type": "recommended", "evidence": [ { "id": "A0A8V0YEP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEP4" } ] }, { "name": "HDHD5", "type": "synonym", "evidence": [ { "id": "XP_004938006", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004938006" } ] } ], "protein_names": [ { "name": "Haloacid dehalogenase-like hydrolase domain-containing 5", "type": "recommended", "evidence": [ { "id": "A0A8V0YEP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEP4/entry#names_and_taxonomy" } ] }, { "name": "haloacid dehalogenase-like hydrolase domain-containing 5 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_004938006", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004938006" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_004938006.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004938006", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004938006" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YEP4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEP4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "HDHD5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEP4", "locus": { "chromosome": "1", "start_pos": 61699323, "end_pos": 61708938, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010011792", "url": "https://www.ensembl.org/id/ENSGALG00010011792" } ] } } ], "crossref": [ { "id": "A0A8V0YEP4", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YEP4", "database": "AlphaFoldDB", "categories": [] }, { "id": "418159", "url": "https://www.ncbi.nlm.nih.gov/gene/418159", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006353", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006353", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006357", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006357", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023214", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023214", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036412", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036412", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050324", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050324", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:418159", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418159", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HDKRMLV", "url": "https://omabrowser.org/oma/group/HDKRMLV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YB09", "url": "https://www.orthodb.org/?gene=A0A8V0YB09", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YCG7", "url": "https://www.orthodb.org/?gene=A0A8V0YCG7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YEP4", "url": "https://www.orthodb.org/?gene=A0A8V0YEP4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14269", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14269", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14269:SF17", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14269:SF17", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13344", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13344", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_004938006", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004938006", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YB09", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB09", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YB09-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB09-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YCG7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCG7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YCG7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCG7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YEP4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEP4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YEP4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEP4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNDIDSGTECTFSMFTDDTKLRGAVNVLQGWDAVQRDQDRLEQWAQPPAFGFLFDIDGVLVRGSQVVPAAREAFRRLSDAGGRLRVPVVFLTNAGNCLRAAKARELSQALGLQVSPEQVILSHSPLRLFSQFHPKCVLVAGQGPVEENARNLGFKHVVTIEALRKAYPLLDMVDQSRRPKELPPPTTGFPTIEGVVLFGEPVRWETSLQLIIDVLLSNGNPGAEPEGIPYPHLPVLACNMDLLWMAEAKMPRFGHGTFLLCLENIYKKVTGRELKYEALIGKPSTVTYRYAEYLIKEQAEKHGWKAPIRRLYAIGDNPMSDVYGANLYNNYLKSAQQNQVEAGVKRIPQAANPQTEDRLAVESCESILVCTGVYRHNADVSRKPEECNMETVFHGHRDFCFDPSLVEASYIVQDVNEAVLLAFEKENWS", "length": 429, "header": "tr|A0A8V0YEP4-1|A0A8V0YEP4_CHICK Isoform 1 of Haloacid dehalogenase-like hydrolase domain-containing 5 OS=Gallus gallus OX=9031 GN=HDHD5 PE=1 SV=1 CANONICAL=A0A8V0YEP4-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YB09-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEP4/entry#A0A8V0YB09-1", "sequence": { "sequence": "MALRGCLRAGRGALRAAGPPGPPARRGCAGGRPPAFGFLFDIDGVLVRGSQVVPAAREAFRRLSDAGGRLRVPVVFLTNAGNCLRAAKARELSQALGLQVSPEQVILSHSPLRLFSQFHPKCVLVAGQGPVEENARNLGFKHVVTIEALRKAYPLLDMVDQSRRPKELPPPTTGFPTIEGVVLFGEPVRWETSLQLIIDVLLSNGNPGAEPEGIPYPHLPVLACNMDLLWMAEAKMPRFGHGTFLLCLENIYKKVTGRELKYEALIGKPSTVTYRYAEYLIKEQAEKHGWKAPIRRLYAIGDNPMSDVYGANLYNNYLKSAQQNQVEAGVKRIPQAANPQTEDRLAVESCESILVCTGVYRHNADVSRKPEECNMETVFHGHRDFCFDPSLVEASYIVQDVNEAVLLAFEKENWS", "length": 415, "header": "tr|A0A8V0YB09-1|A0A8V0YB09_CHICK Computationally mapped isoform of Haloacid dehalogenase-like hydrolase domain-containing 5 OS=Gallus gallus OX=9031 GN=HDHD5 PE=1 SV=1 CANONICAL=A0A8V0YEP4-1" }, "locus": { "chromosome": "1", "start_pos": 61707587, "end_pos": 61702957, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028189.1", "url": "https://www.ensembl.org/id/ENSGALT00010028189.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016157.1", "url": "https://www.ensembl.org/id/ENSGALP00010016157.1" } ] } }, { "isoform_ac": "A0A8V0YCG7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEP4/entry#A0A8V0YCG7-1", "sequence": { "sequence": "MLKVIHAKTALRQESGDRNPLQKAKWHRFVSTATKGTFGSSQPPAFGFLFDIDGVLVRGSQVVPAAREAFRRLSDAGGRLRVPVVFLTNAGNCLRAAKARELSQALGLQVSPEQVILSHSPLRLFSQFHPKCVLVAGQGPVEENARNLGFKHVVTIEALRKAYPLLDMVDQSRRPKELPPPTTGFPTIEGVVLFGEPVRWETSLQLIIDVLLSNGNPGAEPEGIPYPHLPVLACNMDLLWMAEAKMPRFGHGTFLLCLENIYKKVTGRELKYEALIGKPSTVTYRYAEYLIKEQAEKHGWKAPIRRLYAIGDNPMSDVYGANLYNNYLKSAQQNQVEAGVKRIPQAANPQTEDRLAVESCESILVCTGVYRHNADVSRKPEECNMETVFHGHRDFCFDPSLVEASYIVQDVNEAVLLAFEKENWS", "length": 425, "header": "tr|A0A8V0YCG7-1|A0A8V0YCG7_CHICK Computationally mapped isoform of Haloacid dehalogenase-like hydrolase domain-containing 5 OS=Gallus gallus OX=9031 GN=HDHD5 PE=1 SV=1 CANONICAL=A0A8V0YEP4-1" }, "locus": { "chromosome": "1", "start_pos": 61707891, "end_pos": 61702957, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028192.1", "url": "https://www.ensembl.org/id/ENSGALT00010028192.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016160.1", "url": "https://www.ensembl.org/id/ENSGALP00010016160.1" } ] } }, { "isoform_ac": "A0A8V0YEP4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEP4/entry#A0A8V0YEP4-1", "sequence": { "sequence": "MNDIDSGTECTFSMFTDDTKLRGAVNVLQGWDAVQRDQDRLEQWAQPPAFGFLFDIDGVLVRGSQVVPAAREAFRRLSDAGGRLRVPVVFLTNAGNCLRAAKARELSQALGLQVSPEQVILSHSPLRLFSQFHPKCVLVAGQGPVEENARNLGFKHVVTIEALRKAYPLLDMVDQSRRPKELPPPTTGFPTIEGVVLFGEPVRWETSLQLIIDVLLSNGNPGAEPEGIPYPHLPVLACNMDLLWMAEAKMPRFGHGTFLLCLENIYKKVTGRELKYEALIGKPSTVTYRYAEYLIKEQAEKHGWKAPIRRLYAIGDNPMSDVYGANLYNNYLKSAQQNQVEAGVKRIPQAANPQTEDRLAVESCESILVCTGVYRHNADVSRKPEECNMETVFHGHRDFCFDPSLVEASYIVQDVNEAVLLAFEKENWS", "length": 429, "header": "tr|A0A8V0YEP4-1|A0A8V0YEP4_CHICK Isoform 1 of Haloacid dehalogenase-like hydrolase domain-containing 5 OS=Gallus gallus OX=9031 GN=HDHD5 PE=1 SV=1 CANONICAL=A0A8V0YEP4-1" }, "locus": { "chromosome": "1", "start_pos": 61708799, "end_pos": 61702957, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028193.1", "url": "https://www.ensembl.org/id/ENSGALT00010028193.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016161.1", "url": "https://www.ensembl.org/id/ENSGALP00010016161.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 186, "start_aa": "Thr", "end_pos": 186, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr186", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:418159", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418159", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0R4IJ50-1", "protein_name": "Haloacid dehalogenase-like hydrolase domain-containing 5", "gene_name": "hdhd5", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAQMFSRLNMLGIGWRGVRFSRKVTNAAVSAQTQRRYSTDVDEQNRHLFGLLFDIDGVLVRGRTPIPAAKQCFRNLVDGDGKYKVPVVFVTNAGNALRQTKAEQLSHLLEVEVSPEQVVLSHSPLRVFTQFHDMCVLVSGQGPVVEVAHNVGFKNVVTIDMLREAYPLLDVVDHHRRPKDTIPQTKDLPHIDAVILFGEPIRWETNLQLIVDVLLTNGRPGNPVTSLHYPHIPVLACNMDLLWMAEAKNPRFGHGMFLVCLESIYKKITGCELKYEALIGKPSVVTYNYAELLIREQAEKLGWTRPVQRLYAIGDNPMADIYGANLYNRYLKAMNRSRTPQVQAQGGVSGQMAADLHCDDAKCSGQVMVGGSFEHCLPEACSSILVCTGVYNRDMPTDPQETLTEHRIFHGHRDFRFDPSLTQPSFIVNDVRDGVELVFQLEGWPLE", "length": 447 }, "evidence": [ { "id": "A0A8V0YEP4", "url": "https://omabrowser.org/oma/group/A0A8V0YEP4/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "D3ZQB6-1", "protein_name": "Haloacid dehalogenase-like hydrolase domain-containing 5", "gene_name": "Hdhd5", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVGLPPPRGSARAAADWLLGCARGGGSRVGETRSLRVRATSAMAALARLGVLGPGRCLWKLPVRLSAEFQGYGPRRGYVADRAERSPTFGLLFDIDGVLVRGHRVIPAALEAFSKLVNSQGQLQVPVVFVTNAGNILQRDKAQELSALLECKVDPDQVILSHSPMKLFLQYHNKRMLVSGQGPLVENARALGFQNVVTVDDLRIAFPELDMVDLQRRPKTMRPRSDFPAIEGVLLLGEPVRWETNLQLITDVLLSNGHPGAGLATAPYPHLPVLASNMDLLWMAEASMPRFGHGTFLLCLETIYRKITGHELKYEGLMGKPSILTYRYAEEVIRQQAERRGWAAPIRKLYAIGTCKWQMVERRSNGLMDKRSSGLQQPGAVLPSWCALVYTVLRTQAPKHLLLEGQSSHSTGTETSASVQSS", "length": 422 }, "evidence": [ { "id": "A0A8V0YEP4", "url": "https://omabrowser.org/oma/group/A0A8V0YEP4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1N6K5-1", "protein_name": "Haloacid dehalogenase-like hydrolase domain-containing 5", "gene_name": "HDHD5", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAALGEAAARWAPGLWRRAVRTAAWLRGRRFASGGTQSPPTFGLLLDIDGVLVRGHQVIPAAQEAFRRLLDPQGQLRVPVVFVTNAGNISQCSKAEELSAQLGFQVEPDQVILSHSPMKLFSQHHDRRMLVSGQGPLVENARALGFKHLVTVDELRAAFPVLDMVDLQRRPKTTLLPRSDFPAIEGVLLLGEPVRWETSLQLITDVLLSDGNPGTGLATAPYPHLPVLASNTDLLWMAEAKMPRFGHGTFLLCLEAIYRKLTGRELCYSGLTGKPSLLTYRYAEGLLARQAARRGWAAPIRSLYAVGDNPMSDIYGANLFHQHLQTQQEGAARSCASILVCTGVYGPQAPSPTVPALGSEGSPFHGHRDFGFRPELLQAAHVVSDLHEAVQLVLRKEGWAL", "length": 401 }, "evidence": [ { "id": "A0A8V0YEP4", "url": "https://omabrowser.org/oma/group/A0A8V0YEP4/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1SHR6-1", "protein_name": "Haloacid dehalogenase-like hydrolase domain-containing 5", "gene_name": "HDHD5", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MIGRAAGRACAVRAGGGPWLRSARWWRGGRPGCGGGRLAGRRAGPRGRRAGGQGRRGPSCLPSVQRPPTFGFLLDIDGVLVRGHRIIPAAQEAFHKLLNPEGQLRVPVVFVTNAGNILQHGKAQELSALLGFQVEPDQVILSHSPMRLFSQHHERRMLVSGQGPLVENARALGFKSLVTVDELRAAFPVLDMVDLQRRPKTTVIWASSWVLLLGEPVRWETSLQLIMDVLLSDGNPGTGLATAPYPHLPVLAMAGCFSGRFGHGTFLLCLEAIYRKVTGKELRYEGLMGKPSLLTYQYAEGLLRRQAERRGWAAPIRNLYAVGDNPMSDIYGANLFHQYLQTARSVGAEEGARGPWKQQPSTARSCTSILVCTGVYSPEAPESPGPGLLEAAHVVSDVHEAVQLVLRKEGWAL", "length": 413 }, "evidence": [ { "id": "A0A8V0YEP4", "url": "https://omabrowser.org/oma/group/A0A8V0YEP4/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q54QC3-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MAIDKTETTTATTTTTTTTTTTTTNDSSFGIVFDIDGVLMRDGVIIPNATQALKLLEDKETSEPKIPYIFMTNNGGFTEEEKANKISKVLQYNIPSDKVMVAHTPVRPLAEKYKDYDVLLISKTHETSKKLADWYGFKNYKSLQQYIEERPFLCPSKYSTFWTQGVSSEYVIKEAKKQLPIKAIILLEDPIDWGECIQIVSDILQSKDGLLRKDYINRADVQSIDFHICNPDFSYAGEFVIPRYTMGAILECIKLLFKTQTGRDLIYTLYGKPYPLTYQYGKQIISNQISKLGFNDGCILKHIYAIGDNPYSDIKGANNLEHEGWISILVKTGCFKGDTNHPEIPAKYVVDNVYDAVKLILKLEGQ", "length": 366 }, "evidence": [ { "id": "A0A8V0YEP4", "url": "https://omabrowser.org/oma/group/A0A8V0YEP4/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q91WM2-1", "protein_name": "Haloacid dehalogenase-like hydrolase domain-containing 5", "gene_name": "Hdhd5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAALAGLGVLGAGRHLWKLPVRLSAGLQGCGPRRGYIAGSAERSPTFGLLFDIDGVLVRGHRVIPAALEAFSKLVNSQGQLRVPVVFVTNAGNILQHNKAQELSDLLRCKVDPDQVILSHSPMKLFLQYHSKQMLVSGQGPLVENARALGFQNVVTIDELRLAFPELDMVDLQRRPKTMRLRSDFPAIEGVLLLGEPVRWETNLQLIMDVLLSNGHPGTGLATAPYPHLPVLASNMDLLWMAEAKMPRFGHGTFLLCLETIYRKITGNELKYEGLMGKPSILTYQYAEDVIRQQAERRGWAAPIRKLYAIGDNPMSDVYGANLFHQYLQMANRGEEEQQTGGQQKQRPSATQSCASILVCTGIYSSQDPGSQVPPPGRRELPFHGHRDFSFSPGLLEASHIVHDVNEAVQLVFHQEGWA", "length": 419 }, "evidence": [ { "id": "A0A8V0YEP4", "url": "https://omabrowser.org/oma/group/A0A8V0YEP4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9BXW7-1", "protein_name": "Haloacid dehalogenase-like hydrolase domain-containing 5", "gene_name": "HDHD5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAWGCVAALGAARGLCWRAARAAAGLQGRPARRCYAVGPAQSPPTFGFLLDIDGVLVRGHRVIPAALKAFRRLVNSQGQLRVPVVFVTNAGNILQHSKAQELSALLGCEVDADQVILSHSPMKLFSEYHEKRMLVSGQGPVMENAQGLGFRNVVTVDELRMAFPLLDMVDLERRLKTTPLPRNDFPRIEGVLLLGEPVRWETSLQLIMDVLLSNGSPGAGLATPPYPHLPVLASNMDLLWMAEAKMPRFGHGTFLLCLETIYQKVTGKELRYEGLMGKPSILTYQYAEDLIRRQAERRGWAAPIRKLYAVGDNPMSDVYGANLFHQYLQKATHDGAPELGAGGTRQQQPSASQSCISILVCTGVYNPRNPQSTEPVLGGGEPPFHGHRDLCFSPGLMEASHVVNDVNEAVQLVFRKEGWALE", "length": 423 }, "evidence": [ { "id": "A0A8V0YEP4", "url": "https://omabrowser.org/oma/group/A0A8V0YEP4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9M169-1", "protein_name": "Hydrolase family protein / HAD-superfamily protein", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MNHLLILARNSLRRRNFNLRPPSRSFSSTISPESNRSSFGIAFDIDGVILLGSSPVGGSPSALRRLYDDSGALKIPFLFLTNGGGLPESKRASEMSHLLGVQVSPLQVIQAHSPFRKLVNRFENELVVAAGKGEPAAVMSNYGFKNVISMDEYASYFDNIDPLAPYKKLMFRQDGHKELRSREDVLSQRVQAAFIVSDPVDWSRDIQVLCDILRTGGLPGKEIGPQPHLYIANDDLDYQTEFPTERLGMGAFRIALESIFNRIHEKPLEYTSFGKPNPFVFKNAEDVLKEIATSPYSSNQGSHHFKTLYMIGDNPKIDIRGARQAGTPWFSILTRTGVFKGKDNHSEFPADLVVDTVEEAVDFILTRESAKQSLLS", "length": 376 }, "evidence": [ { "id": "A0A8V0YEP4", "url": "https://omabrowser.org/oma/group/A0A8V0YEP4/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YEP4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEP4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "glycerophospholipid biosynthetic process", "id": "GO:0046474", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046474", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YEP4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEP4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 427, "end_pos": 429, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 186 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 427, "end_pos": 429 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", 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0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YEQ3-1", "uniprot_ac": "A0A8V0YEQ3", "uniprot_id": "A0A8V0YEQ3_CHICK", "mass": { "chemical_mass": 13649.0, "monoisotopic_mass": 13649.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Reverse transcriptase/retrotransposon-derived protein RNase H-like domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A8V0YEQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEQ3/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YEQ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEQ3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEQ3", "locus": {} } ], "crossref": [ { "id": "A0A8V0YEQ3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YEQ3", "database": "AlphaFoldDB", "categories": [] }, { "id": "A0A8V0YEQ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEQ3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YEQ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEQ3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVEKQLLATYSALQAVEPITQIAEVIVKTTLPIQGWVKDLTHIPKTGVAQSQTVARWVAYLSQRSRLSSSPLKEELQKILGPVTYHSETPEEIVVTCPEKSPVQEGKYPIPEDAWYTDGSSRG", "length": 123, "header": "tr|A0A8V0YEQ3-1|A0A8V0YEQ3_CHICK Isoform 1 of Reverse transcriptase/retrotransposon-derived protein RNase H-like domain-containing protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0YEQ3-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YEQ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEQ3/entry#A0A8V0YEQ3-1", "sequence": { "sequence": "MVEKQLLATYSALQAVEPITQIAEVIVKTTLPIQGWVKDLTHIPKTGVAQSQTVARWVAYLSQRSRLSSSPLKEELQKILGPVTYHSETPEEIVVTCPEKSPVQEGKYPIPEDAWYTDGSSRG", "length": 123, "header": "tr|A0A8V0YEQ3-1|A0A8V0YEQ3_CHICK Isoform 1 of Reverse transcriptase/retrotransposon-derived protein RNase H-like domain-containing protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0YEQ3-1" }, "locus": { "chromosome": "W", "start_pos": 5614528, "end_pos": 5614160, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029873.1", "url": "https://www.ensembl.org/id/ENSGALT00010029873.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017395.1", "url": "https://www.ensembl.org/id/ENSGALP00010017395.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": 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"https://www.uniprot.org/uniprotkb/A0A8V0YET0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YET4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YET4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YET4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YET4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSLPQDRNRSSCSSETLAKCLQARKDLETAISGIVKAEQQIKENWREVKAKIHSHISRQLECLRSREVWLFEQVDLIQQLKEEALQQQAQQLYWYLGQFNCLIHQLEHSYNNELANQISICLERLESLTLKPEESSVLNFEADTSYLRQAITSFGSIKTMQTSERENTSPWFPGQNCALTNCEQQKTLCGTVGTSLADWLLGSRPVDVCRAPYIPSTNLEEWVTQKSVSEPSQDLSSSKVCYFERAWGNLKDLENWLLRNQQHDVAGKTDAPGHKDSTLTSNSSFSMEKKVEELESLVQEEVDLSDWLLTPGVENGGSASDEKWKYEFKPFREEFNCNDWLLKAETCTSCRGSQIKSVEIENLGNLKCLNEHLDGKKLPTTSAVNAWLLQHPQPPFKMEDVCKANELCSSFSECVCDENCGKEALCKWLLKKEGKDKNGVPVSQKAVPNVEHEKTKSLVSSWLNPSQQLSGEPVSAEKVDYSAEIAEPFKVLLERPLTSWLAKSEHKAESADEKASREKVNSSSRSPFVDLLAPFHHPLNVNSWVLASNNLENDNPPPVEDKWLLHKKAQEFGLPTVCDLFACMKLNGDNEKWLYRTTLQVGTGGIGIVPFLLTNRTSC", "length": 619, "header": "tr|A0A8V0YEQ9-1|A0A8V0YEQ9_CHICK Isoform 1 of Nuclear receptor coactivator 4 OS=Gallus gallus OX=9031 GN=NCOA4 PE=4 SV=1 CANONICAL=A0A8V0YEQ9-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Y1N2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEQ9/entry#A0A8V0Y1N2-1", "sequence": { "sequence": "MAALDASSVIARNTLRMSLPQDRNRSSCSSETLAKCLQARKDLETAISGIVKAEQQIKENWREVKAKIHSHISRQLECLRSREVWLFEQVDLIQQLKEEALQQQAQQLYWYLGQFNCLIHQLEHSYNNELANQISICLERLESLTLKPEESSVLNFEADTSYLRQAITSFGSIKTMQTSERENTSPWFPGQNCALTNCEQQKTLCGTVGTSLADWLLGSRPVDVCRAPYIPSTNLEEWVTQKSVSEPSQDLSSSKVCYFERAWGNLKDLENWLLRNQQHDVAGKTDAPGHKDSTLTSNSSFSMEKKVEELESLVQEEVDLSDWLLTPGVENGGSASDEKWKYEFKPFREEFNCNDWLLKAETCTSCRGSQIKSVEIENLGNLKCLNEHLDGKKLPTTSAVNAWLLQHPQPPFKMEDVCKANELCSSFSECVCDENCGKEALCKWLLKKEGKDKNGVPVSQKAVPNVEHEKTKSLVSSWLNPSQQLSGEPVSAEKVDYSAEIAEPFKVLLERPLTSWLAKSEHKAESADEKASREKVNSSSRSPFVDLLAPFHHPLNVNSWVLASNNLENDNPPPVEDKWLLHKKAQEFGLPTVCDLFACMKLNGDNEKWLYRTTLQM", "length": 617, "header": "tr|A0A8V0Y1N2-1|A0A8V0Y1N2_CHICK Computationally mapped isoform of Nuclear receptor coactivator 4 OS=Gallus gallus OX=9031 GN=NCOA4 PE=4 SV=1 CANONICAL=A0A8V0YEQ9-1" }, "locus": { "chromosome": "6", "start_pos": 3461130, "end_pos": 3454945, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010025698.1", "url": "https://www.ensembl.org/id/ENSGALT00010025698.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010014483.1", "url": "https://www.ensembl.org/id/ENSGALP00010014483.1" } ] } }, { "isoform_ac": "A0A8V0Y7U7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEQ9/entry#A0A8V0Y7U7-1", "sequence": { "sequence": "MAPRNTLRMSLPQDRNRSSCSSETLAKCLQARKDLETAISGIVKAEQQIKENWREVKAKIHSHISRQLECLRSREVWLFEQVDLIQQLKEEALQQQAQQLYWYLGQFNCLIHQLEHSYNNELANQISICLERLESLTLKPEESSVLNFEADTSYLRQAITSFGSIKTMQTSERENTSPWFPGQNCALTNCEQQKTLCGTVGTSLADWLLGSRPVDVCRAPYIPSTNLEEWVTQKSVSEPSQDLSSSKVCYFERAWGNLKDLENWLLRNQQHDVAGKTDAPGHKDSTLTSNSSFSMEKKVEELESLVQEEVDLSDWLLTPGVENGGSASDEKWKYEFKPFREEFNCNDWLLKAETCTSCRGSQIKSVEIENLGNLKCLNEHLDGKKLPTTSAVNAWLLQHPQPPFKMEDVCKANELCSSFSECVCDENCGKEALCKWLLKKEGKDKNGVPVSQKAVPNVEHEKTKSLVSSWLNPSQQLSGEPVSAEKVDYSAEIAEPFKVLLERPLTSWLAKSEHKAESADEKASREKVNSSSRSPFVDLLAPFHHPLNVNSWVLASNNLENDNPPPVEDKWLLHKKAQEFGLPTVCDLFACMKLNGDNEKWLYRTTLQM", "length": 609, "header": "tr|A0A8V0Y7U7-1|A0A8V0Y7U7_CHICK Computationally mapped isoform of Nuclear receptor coactivator 4 OS=Gallus gallus OX=9031 GN=NCOA4 PE=4 SV=1 CANONICAL=A0A8V0YEQ9-1" }, "locus": { "chromosome": "6", "start_pos": 3461130, "end_pos": 3455207, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010025694.1", "url": "https://www.ensembl.org/id/ENSGALT00010025694.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010014480.1", "url": "https://www.ensembl.org/id/ENSGALP00010014480.1" } ] } }, { "isoform_ac": "A0A8V0YEQ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEQ9/entry#A0A8V0YEQ9-1", "sequence": { "sequence": "MSLPQDRNRSSCSSETLAKCLQARKDLETAISGIVKAEQQIKENWREVKAKIHSHISRQLECLRSREVWLFEQVDLIQQLKEEALQQQAQQLYWYLGQFNCLIHQLEHSYNNELANQISICLERLESLTLKPEESSVLNFEADTSYLRQAITSFGSIKTMQTSERENTSPWFPGQNCALTNCEQQKTLCGTVGTSLADWLLGSRPVDVCRAPYIPSTNLEEWVTQKSVSEPSQDLSSSKVCYFERAWGNLKDLENWLLRNQQHDVAGKTDAPGHKDSTLTSNSSFSMEKKVEELESLVQEEVDLSDWLLTPGVENGGSASDEKWKYEFKPFREEFNCNDWLLKAETCTSCRGSQIKSVEIENLGNLKCLNEHLDGKKLPTTSAVNAWLLQHPQPPFKMEDVCKANELCSSFSECVCDENCGKEALCKWLLKKEGKDKNGVPVSQKAVPNVEHEKTKSLVSSWLNPSQQLSGEPVSAEKVDYSAEIAEPFKVLLERPLTSWLAKSEHKAESADEKASREKVNSSSRSPFVDLLAPFHHPLNVNSWVLASNNLENDNPPPVEDKWLLHKKAQEFGLPTVCDLFACMKLNGDNEKWLYRTTLQVGTGGIGIVPFLLTNRTSC", "length": 619, "header": "tr|A0A8V0YEQ9-1|A0A8V0YEQ9_CHICK Isoform 1 of Nuclear receptor coactivator 4 OS=Gallus gallus OX=9031 GN=NCOA4 PE=4 SV=1 CANONICAL=A0A8V0YEQ9-1" }, "locus": { "chromosome": "6", "start_pos": 3461187, "end_pos": 3455911, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010025675.1", "url": "https://www.ensembl.org/id/ENSGALT00010025675.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010014468.1", "url": "https://www.ensembl.org/id/ENSGALP00010014468.1" } ] } }, { "isoform_ac": "A0A8V0YET0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEQ9/entry#A0A8V0YET0-1", "sequence": { "sequence": "MSLPQDRNRSSCSSETLAKCLQARKDLETAISGIVKAEQQIKENWREVKAKIHSHISRQLECLRSREVWLFEQVDLIQQLKEEALQQQAQQLYWYLGQFNCLIHQLEHSYNNELANQISICLERLESLTLKPEESSVLNFEADTSYLRQAITSFGSIKTMQTSERENTSPWFPGQNCALTNCEQQKTLCGTVGTSLADWLLGSRPVDVCRAPYIPSTNLEEWVTQKSVSEPSQDLSSSKVCYFERAWGNLKDLENWLLRNQQHDVAGKTDAPGHKDSTLTSNSSFSMEKKVEELESLVQEEVDLSDWLLTPGVENGGSASDEKWKYEFKPFREEFNCNDWLLKAETCTSCRGSQIKSVEIENLGNLKCLNEHLDGKKLPTTSAVNAWLLQHPQPPFKMEDVCKANELCSSFSECVCDENCGKEALCKWLLKKEGKDKNGVPVSQKAVPNVEHEKTKSLVSSWLNPSQQLSGEPVSAEKVDYSAEIAEPFKVLLERPLTSWLAKSEHKAESADEKASREKVNSSSRSPFVDLLAPFHHPLNVNSWVLASNNLENDNPPPVEDKWLLHKKAQEFGLPTVCDLFACMKLNGDNEKWLYRTTLQVGCEELEALELSPSC", "length": 615, "header": "tr|A0A8V0YET0-1|A0A8V0YET0_CHICK Computationally mapped isoform of Nuclear receptor coactivator 4 OS=Gallus gallus OX=9031 GN=NCOA4 PE=4 SV=1 CANONICAL=A0A8V0YEQ9-1" }, "locus": { "chromosome": "6", "start_pos": 3461167, "end_pos": 3455911, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010025708.1", "url": "https://www.ensembl.org/id/ENSGALT00010025708.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010014489.1", "url": "https://www.ensembl.org/id/ENSGALP00010014489.1" } ] } }, { "isoform_ac": "A0A8V0YET4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEQ9/entry#A0A8V0YET4-1", "sequence": { "sequence": "MLRNTLRMSLPQDRNRSSCSSETLAKCLQARKDLETAISGIVKAEQQIKENWREVKAKIHSHISRQLECLRSREVWLFEQVDLIQQLKEEALQQQAQQLYWYLGQFNCLIHQLEHSYNNELANQISICLERLESLTLKPEESSVLNFEADTSYLRQAITSFGSIKTMQTSERENTSPWFPGQNCALTNCEQQKTLCGTVGTSLADWLLGSRPVDVCRAPYIPSTNLEEWVTQKSVSEPSQDLSSSKVCYFERAWGNLKDLENWLLRNQQHDVAGKTDAPGHKDSTLTSNSSFSMEKKVEELESLVQEEVDLSDWLLTPGVENGGSASDEKWKYEFKPFREEFNCNDWLLKAETCTSCRGSQIKSVEIENLGNLKCLNEHLDGKKLPTTSAVNAWLLQHPQPPFKMEDVCKANELCSSFSECVCDENCGKEALCKWLLKKEGKDKNGVPVSQKAVPNVEHEKTKSLVSSWLNPSQQLSGEPVSAEKVDYSAEIAEPFKVLLERPLTSWLAKSEHKAESADEKASREKVNSSSRSPFVDLLAPFHHPLNVNSWVLASNNLENDNPPPVEDKWLLHKKAQEFGLPTVCDLFACMKLNGDNEKWLYRTTLQM", "length": 608, "header": "tr|A0A8V0YET4-1|A0A8V0YET4_CHICK Computationally mapped isoform of Nuclear receptor coactivator 4 OS=Gallus gallus OX=9031 GN=NCOA4 PE=4 SV=1 CANONICAL=A0A8V0YEQ9-1" }, "locus": { "chromosome": "6", "start_pos": 3461130, "end_pos": 3450233, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010025716.1", "url": "https://www.ensembl.org/id/ENSGALT00010025716.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010014494.1", "url": "https://www.ensembl.org/id/ENSGALP00010014494.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "B1H215-1", "protein_name": "Nuclear receptor coactivator 4", "gene_name": "Ncoa4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAQGTVSRMNTSLEQSGCCSSRETLLRCSDARRELELAIGGVLRAEQQMKDNLREVKAQIHSCISRHLECLRSREVWLNEQVDLIYQLKEETLQQQAQQLYWLMGQFNCLIHQLEITQNKDLANQVALCLERLGSLTLKPEDSTVLLFEADASALRQTITTFGSLKTIQIPEHLMAHPSSSSVRPFLEKRGYTQVPEQKSASSGTAVSLSEWLLVSKPAIGPQAPYVPSTNPQDWLTPKQTLENSQTSARICSDAWGNLKGLENWLLNSHQQEIPGKPSSSKCNSHCSTSSFSTEDEKVEDVEVLDQDELDLSDWLVTPQEPRDLEKPVNGRSDTSDKFKLLFQVFREPYNVNDWLVKPDSCTNCQGNQPRGVEIENLGNLKCLNDHLEAKKSLPVPGVITEGWLVQNHQDTCKVEEVCKANEPCTSFAECVCDDSCEKEAMHKWLLKKEGKDKNGMPMGPKSESEKHRESLSLWLCPSRNELTEHAKTPKTTAPARIADSFHIIRNSSLSEWLIGPTCKGGGPKEVPNMEERASKEMLKSPMATYWRPFNTADWVLPGKKVGNLSQFSSGEDKWLLRKKAQEVFLNSPLQEERNFRSDCYGLPAVCDLFACMQLKVDKDKWLYRAPLQM", "length": 630 }, "evidence": [ { "id": "A0A8V0YEQ9", "url": "https://omabrowser.org/oma/group/A0A8V0YEQ9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1SDW1-1", "protein_name": "Nuclear receptor coactivator 4", "gene_name": "NCOA4", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSTSQDQNGCSSNKEPLLRCCDARRDLELAIGGVLRAEQQIKDNLREVKAQIHSCISRHLECLRSREVWLYEQVDLIYQLKEETLQQQAQQLYWLLGQFNCLIHQLECTQNKDLANQVSVCLERLGGLTLKPEDSTVLLFETDTTALRQAITTFGSLKTIQIPEHLMAHASSSNIGPFLEKRGYIPFPEQKLASSTAVVPLSEWLLGSKPASGRQAPYIPSTNLQDWLTQKQTLENSQTSARACSFFNNVWGNLKGLENWLHKGQQQEVSEKPSYEKCNSSPTTSSYSIETEKVGDLELLDQDEMDLSDWLMTPQESHKLEKPRNGSYETSEKFKLLFQVFQESYSVNDWLVKPDSCTSCQGNQPKGVEIENLGNLKCLNDHLEAKKPLSTPSVITEDWLVQNRQDPYKVEEVCKANEPCTSFAECVCDENCEKEALCKWLLKKEGKDKNGMPVEPKPEPEKHKDSLNMWLCQSRKEATEQVKSSKAMASRIADSFQIIKNSPLSEWLITPSGKEGCSKEVPSTQDRAGKQKLPTSWCPFNTADWVLPGKKTGNLSQLSSGEDKWILRKKAKEVLLNSPLREEHNFPPERYGLPAVCDLFACMQLKVDKEKWLYRTPLQM", "length": 620 }, "evidence": [ { "id": "A0A8V0YEQ9", "url": "https://omabrowser.org/oma/group/A0A8V0YEQ9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q13772-1", "protein_name": "Nuclear receptor coactivator 4", "gene_name": "NCOA4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNTFQDQSGSSSNREPLLRCSDARRDLELAIGGVLRAEQQIKDNLREVKAQIHSCISRHLECLRSREVWLYEQVDLIYQLKEETLQQQAQQLYSLLGQFNCLTHQLECTQNKDLANQVSVCLERLGSLTLKPEDSTVLLFEADTITLRQTITTFGSLKTIQIPEHLMAHASSANIGPFLEKRGCISMPEQKSASGIVAVPFSEWLLGSKPASGYQAPYIPSTDPQDWLTQKQTLENSQTSSRACNFFNNVGGNLKGLENWLLKSEKSSYQKCNSHSTTSSFSIEMEKVGDQELPDQDEMDLSDWLVTPQESHKLRKPENGSRETSEKFKLLFQSYNVNDWLVKTDSCTNCQGNQPKGVEIENLGNLKCLNDHLEAKKPLSTPSMVTEDWLVQNHQDPCKVEEVCRANEPCTSFAECVCDENCEKEALYKWLLKKEGKDKNGMPVEPKPEPEKHKDSLNMWLCPRKEVIEQTKAPKAMTPSRIADSFQVIKNSPLSEWLIRPPYKEGSPKEVPGTEDRAGKQKFKSPMNTSWCSFNTADWVLPGKKMGNLSQLSSGEDKWLLRKKAQEVLLNSPLQEEHNFPPDHYGLPAVCDLFACMQLKVDKEKWLYRTPLQM", "length": 614 }, "evidence": [ { "id": "A0A8V0YEQ9", "url": "https://omabrowser.org/oma/group/A0A8V0YEQ9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q5U4H9-1", "protein_name": "Nuclear receptor coactivator 4", "gene_name": "Ncoa4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNTSLEQSGCYSNRETLLRCSDARRELELAIGGVLRAEQQIKDNLREVKAQIHSCISRHLECLRSREVWLNEQVDLIYQLKEETLQQQAQQLYWLMGQFNCLIHQLEYTQNKDLANQVSVCLERLGSLALKPEDSTVLLFEADTSALRQTITTFGSLKTIQIPEHLMAHASSSSIGPFLEKRGYIQVPEQKSASSGTAVSLSEWLLVSKPAIGLQAPYVPSTNPQDWLIPKQTSENSQTSARACSFFSDAWGNLKGLENWLLNSHQQEIAGKPSSSKCNSHCSTSSFSPEAEKAEDVELLDQDELDLSDWLVTPQEPCELEKPVDGSWETSEKFKLLFQVFREPYNVSDWLVKPDSCTNCQGNQPRGVEIENLGNLKCLNDHLEAKKSVSVPGATISDGWLAQNHQDTWKVEEVCKANEPCTSFAECVCDDNCEKEAMYKWLLKKGGKDKNGMPMEPKSEPEKHRESLTLWLCPSRNELTEQAKAPKAMAPARIADSFHVIKNSSLSEWLMGPTCKGGPKDVPNTEERAGKEMLQSSMATSWCPFNTADWVLPGKKVGSLSQFPSGEDKWLLRKKAQEAFLNSPLQEERNFRPDCYGLPAVCDLFACMQLKVDKEKWLYRTPLQM", "length": 625 }, "evidence": [ { "id": "A0A8V0YEQ9", "url": "https://omabrowser.org/oma/group/A0A8V0YEQ9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "transcription coactivator activity", "id": "GO:0003713", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003713", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YEQ9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEQ9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "intracellular iron ion homeostasis", "id": "GO:0006879", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006879", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YEQ9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEQ9" } ], "pmid": "" }, { "name": "response to hormone", "id": "GO:0009725", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009725", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YEQ9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEQ9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "autolysosome", "id": "GO:0044754", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044754", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YEQ9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEQ9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 167, "end_pos": 169, "annotation": "n_glycosylation_sequon" }, { "start_pos": 282, "end_pos": 284, "annotation": "n_glycosylation_sequon" }, { "start_pos": 521, "end_pos": 523, "annotation": "n_glycosylation_sequon" }, { "start_pos": 615, "end_pos": 617, "annotation": "n_glycosylation_sequon" }, { "start_pos": 8, "end_pos": 10, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YEQ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEQ9" }, { "id": "PF12489", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12489" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Nuclear receptor coactivator 4 N-terminal", "eco_id": "ECO_0000259", "start_pos": 16, "end_pos": 145, "start_aa": "Thr", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 167, "end_pos": 169 }, { "start_pos": 282, "end_pos": 284 }, { "start_pos": 521, "end_pos": 523 }, { "start_pos": 615, "end_pos": 617 }, { "start_pos": 8, "end_pos": 10 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { 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"recommended", "evidence": [ { "id": "F1NVF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NVF2" } ] } ], "protein_names": [ { "name": "mitogen-activated protein kinase kinase", "type": "recommended", "evidence": [ { "id": "F1NVF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NVF2/entry#names_and_taxonomy" } ] }, { "name": "2.7.12.2", "type": "synonym", "evidence": [ { "id": "F1NVF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NVF2/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NVF2", "url": "https://www.uniprot.org/uniprotkb/F1NVF2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MAP2K6", "url": "https://www.uniprot.org/uniprotkb/F1NVF2", "locus": { "chromosome": "18", "start_pos": 8651141, "end_pos": 8611185, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029424", "url": "https://www.ensembl.org/id/ENSGALG00010029424" } ] } } ], "crossref": [ { "id": "F1NVF2", "url": "https://alphafold.ebi.ac.uk/entry/F1NVF2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000004370", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000004370", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd06617", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06617", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "417445", "url": "https://www.ncbi.nlm.nih.gov/gene/417445", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000719", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000719", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008271", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008271", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011009", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011009", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017441", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017441", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:417445", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417445", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A1D5PHN6", "url": "https://www.orthodb.org/?gene=A0A1D5PHN6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ACY9", "url": "https://www.orthodb.org/?gene=A0A8V1ACY9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AIA8", "url": "https://www.orthodb.org/?gene=A0A8V1AIA8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AK71", "url": "https://www.orthodb.org/?gene=A0A8V1AK71", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AM65", "url": "https://www.orthodb.org/?gene=A0A8V1AM65", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ANQ4", "url": "https://www.orthodb.org/?gene=A0A8V1ANQ4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NVF2", "url": "https://www.orthodb.org/?gene=F1NVF2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48013", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48013", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR48013:SF12", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48013:SF12", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00069", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00069", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-168638", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-168638", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-2559580", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2559580", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-450302", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-450302", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-6811555", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6811555", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9020702", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9020702", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9833482", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9833482", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "10596", "url": "https://www.rhea-db.org/rhea/10596", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "17989", "url": "https://www.rhea-db.org/rhea/17989", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "46608", "url": "https://www.rhea-db.org/rhea/46608", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A1D5PHN6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PHN6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PHN6-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PHN6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ACY9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACY9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ACY9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACY9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AIA8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIA8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AIA8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIA8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AK71", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AK71", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AK71-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AK71-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AM65", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM65", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AM65-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM65-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ANQ4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANQ4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ANQ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANQ4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NVF2", "url": "https://www.uniprot.org/uniprotkb/F1NVF2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NVF2-1", "url": "https://www.uniprot.org/uniprotkb/F1NVF2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSQSRGKKRNPGLKIPKEAFEQPQTSSTPPRDLDSKACISIGEENFEVKADDLEPISELGRGAYGVVEKMRHMPSGQIMAVKRIRATVNSQEQKRLLMDLDISMRTVDCPFTVTFYGALFREGDVWICMELMDTSLDKFYKHVIDKGLTIPEDILGKIAVSIVKALEHLHSKLSVIHRDVKPSNVLINTQGQVKMCDFGISGYLVDSVAKTMDAGCKPYMAPERINPELNQKGYSVKSDIWSLGITMIELAILRFPYDSWGTPFQQLKQVVEEPSPQLPADKFSAEFVDFTSQCLKKNSKERPTYPELMQHPFFTLHESKETDVASFVKLILGD", "length": 334, "header": "tr|F1NVF2-1|F1NVF2_CHICK Isoform 1 of mitogen-activated protein kinase kinase OS=Gallus gallus OX=9031 GN=MAP2K6 PE=3 SV=2 CANONICAL=F1NVF2-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PHN6-1", "url": "https://www.uniprot.org/uniprotkb/F1NVF2/entry#A0A1D5PHN6-1", "sequence": { "sequence": "MKLLQNSGDEMKGKKRNPGLKIPKEAFEQPQTSSTPPRDLDSKACISIGEENFEVKADDLEPISELGRGAYGVVEKMRHMPSGQIMAVKRIRATVNSQEQKRLLMDLDISMRTVDCPFTVTFYGALFREGDVWICMELMDTSLDKFYKHVIDKGLTIPEDILGKIAVSIVKALEHLHSKLSVIHRDVKPSNVLINTQGQVKMCDFGISGYLVDSVAKTMDAGCKPYMAPERINPELNQKGYSVKSDIWSLGITMIELAILRFPYDSWGTPFQQLKQVVEEPSPQLPADKFSAEFVDFTSQCLKKNSKERPTYPELMQHPFFTLHESKETDVASFVKLILGD", "length": 341, "header": "tr|A0A1D5PHN6-1|A0A1D5PHN6_CHICK Computationally mapped isoform of mitogen-activated protein kinase kinase OS=Gallus gallus OX=9031 GN=MAP2K6 PE=3 SV=2 CANONICAL=F1NVF2-1" }, "locus": { "chromosome": "18", "start_pos": 8648228, "end_pos": 8613622, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071187.1", "url": "https://www.ensembl.org/id/ENSGALT00010071187.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043878.1", "url": "https://www.ensembl.org/id/ENSGALP00010043878.1" } ] } }, { "isoform_ac": "A0A8V1ACY9-1", "url": "https://www.uniprot.org/uniprotkb/F1NVF2/entry#A0A8V1ACY9-1", "sequence": { "sequence": "MAGRDAHRGKKRNPGLKIPKEAFEQPQTSSTPPRDLDSKACISIGEENFEVKADDLEPISELGRGAYGVVEKMRHMPSGQIMAVKRIRATVNSQEQKRLLMDLDISMRTVDCPFTVTFYGALFREGDVWICMELMDTSLDKFYKHVIDKGLTIPEDILGKIAVSIVKALEHLHSKLSVIHRDVKPSNVLINTQGQVKMCDFGISGYLVDSVAKTMDAGCKPYMAPERINPELNQKGYSVKSDIWSLGITMIELAILRFPYDSWGTPFQQLKQVVEEPSPQLPADKFSAEFVDFTSQCLKKNSKERPTYPELMQHPFFTLHESKETDVASFVKLILGD", "length": 337, "header": "tr|A0A8V1ACY9-1|F1NVF2_CHICK Computationally mapped isoform of mitogen-activated protein kinase kinase OS=Gallus gallus OX=9031 GN=MAP2K6 PE=3 SV=1 CANONICAL=F1NVF2-1" }, "locus": { "chromosome": "18", "start_pos": 8648228, "end_pos": 8612384, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071188.1", "url": "https://www.ensembl.org/id/ENSGALT00010071188.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043879.1", "url": "https://www.ensembl.org/id/ENSGALP00010043879.1" } ] } }, { "isoform_ac": "A0A8V1AIA8-1", "url": "https://www.uniprot.org/uniprotkb/F1NVF2/entry#A0A8V1AIA8-1", "sequence": { "sequence": "MHTSVQIYGKKRNPGLKIPKEAFEQPQTSSTPPRDLDSKACISIGEENFEVKADDLEPISELGRGAYGVVEKMRHMPSGQIMAVKRIRATVNSQEQKRLLMDLDISMRTVDCPFTVTFYGALFREGDVWICMELMDTSLDKFYKHVIDKGLTIPEDILGKIAVSIVKALEHLHSKLSVIHRDVKPSNVLINTQGQVKMCDFGISGYLVDSVAKTMDAGCKPYMAPERINPELNQKGYSVKSDIWSLGITMIELAILRFPYDSWGTPFQQLKQVVEEPSPQLPADKFSAEFVDFTSQCLKKNSKERPTYPELMQHPFFTLHESKETDVASFVKLILGD", "length": 337, "header": "tr|A0A8V1AIA8-1|F1NVF2_CHICK Computationally mapped isoform of mitogen-activated protein kinase kinase OS=Gallus gallus OX=9031 GN=MAP2K6 PE=3 SV=1 CANONICAL=F1NVF2-1" }, "locus": { "chromosome": "18", "start_pos": 8648228, "end_pos": 8611470, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071190.1", "url": "https://www.ensembl.org/id/ENSGALT00010071190.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043881.1", "url": "https://www.ensembl.org/id/ENSGALP00010043881.1" } ] } }, { "isoform_ac": "A0A8V1AK71-1", "url": "https://www.uniprot.org/uniprotkb/F1NVF2/entry#A0A8V1AK71-1", "sequence": { "sequence": "MSRHGATVNSQEQKRLLMDLDISMRTVDCPFTVTFYGALFREGDVWICMELMDTSLDKFYKHVIDKGLTIPEDILGKIAVSIVKALEHLHSKLSVIHRDVKPSNVLINTQGQVKMCDFGISGYLVDSVAKTMDAGCKPYMAPERINPELNQKGYSVKSDIWSLGITMIELAILRFPYDSWGTPFQQLKQVVEEPSPQLPADKFSAEFVDFTSQCLKKNSKERPTYPELMQHPFFTLHESKETDVASFVKLILGD", "length": 254, "header": "tr|A0A8V1AK71-1|F1NVF2_CHICK Computationally mapped isoform of mitogen-activated protein kinase kinase OS=Gallus gallus OX=9031 GN=MAP2K6 PE=3 SV=1 CANONICAL=F1NVF2-1" }, "locus": { "chromosome": "18", "start_pos": 8648228, "end_pos": 8636517, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071182.1", "url": "https://www.ensembl.org/id/ENSGALT00010071182.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043873.1", "url": "https://www.ensembl.org/id/ENSGALP00010043873.1" } ] } }, { "isoform_ac": "A0A8V1AM65-1", "url": "https://www.uniprot.org/uniprotkb/F1NVF2/entry#A0A8V1AM65-1", "sequence": { "sequence": "MGFSFRSEGKKRNPGLKIPKEAFEQPQTSSTPPRDLDSKACISIGEENFEVKADDLEPISELGRGAYGVVEKMRHMPSGQIMAVKRIRATVNSQEQKRLLMDLDISMRTVDCPFTVTFYGALFREGDVWICMELMDTSLDKFYKHVIDKGLTIPEDILGKIAVSIVKALEHLHSKLSVIHRDVKPSNVLINTQGQVKMCDFGISGYLVDSVAKTMDAGCKPYMAPERINPELNQKGYSVKSDIWSLGITMIELAILRFPYDSWGTPFQQLKQVVEEPSPQLPADKFSAEFVDFTSQCLKKNSKERPTYPELMQHPFFTLHESKETDVASFVKLILGD", "length": 337, "header": "tr|A0A8V1AM65-1|F1NVF2_CHICK Computationally mapped isoform of mitogen-activated protein kinase kinase OS=Gallus gallus OX=9031 GN=MAP2K6 PE=3 SV=1 CANONICAL=F1NVF2-1" }, "locus": { "chromosome": "18", "start_pos": 8648228, "end_pos": 8627032, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071186.1", "url": "https://www.ensembl.org/id/ENSGALT00010071186.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043877.1", "url": "https://www.ensembl.org/id/ENSGALP00010043877.1" } ] } }, { "isoform_ac": "A0A8V1ANQ4-1", "url": "https://www.uniprot.org/uniprotkb/F1NVF2/entry#A0A8V1ANQ4-1", "sequence": { "sequence": "MGPPRDLDSKACISIGEENFEVKADDLEPISELGRGAYGVVEKMRHMPSGQIMAVKRIRATVNSQEQKRLLMDLDISMRTVDCPFTVTFYGALFREGDVWICMELMDTSLDKFYKHVIDKGLTIPEDILGKIAVSIVKALEHLHSKLSVIHRDVKPSNVLINTQGQVKMCDFGISGYLVDSVAKTMDAGCKPYMAPERINPELNQKGYSVKSDIWSLGITMIELAILRFPYDSWGTPFQQLKQVVEEPSPQLPADKFSAEFVDFTSQCLKKNSKERPTYPELMQHPFFTLHESKETDVASFVKLILGD", "length": 308, "header": "tr|A0A8V1ANQ4-1|F1NVF2_CHICK Computationally mapped isoform of mitogen-activated protein kinase kinase OS=Gallus gallus OX=9031 GN=MAP2K6 PE=3 SV=1 CANONICAL=F1NVF2-1" }, "locus": { "chromosome": "18", "start_pos": 8648228, "end_pos": 8632535, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071184.1", "url": "https://www.ensembl.org/id/ENSGALT00010071184.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043875.1", "url": "https://www.ensembl.org/id/ENSGALP00010043875.1" } ] } }, { "isoform_ac": "F1NVF2-1", "url": "https://www.uniprot.org/uniprotkb/F1NVF2/entry#F1NVF2-1", "sequence": { "sequence": "MSQSRGKKRNPGLKIPKEAFEQPQTSSTPPRDLDSKACISIGEENFEVKADDLEPISELGRGAYGVVEKMRHMPSGQIMAVKRIRATVNSQEQKRLLMDLDISMRTVDCPFTVTFYGALFREGDVWICMELMDTSLDKFYKHVIDKGLTIPEDILGKIAVSIVKALEHLHSKLSVIHRDVKPSNVLINTQGQVKMCDFGISGYLVDSVAKTMDAGCKPYMAPERINPELNQKGYSVKSDIWSLGITMIELAILRFPYDSWGTPFQQLKQVVEEPSPQLPADKFSAEFVDFTSQCLKKNSKERPTYPELMQHPFFTLHESKETDVASFVKLILGD", "length": 334, "header": "tr|F1NVF2-1|F1NVF2_CHICK Isoform 1 of mitogen-activated protein kinase kinase OS=Gallus gallus OX=9031 GN=MAP2K6 PE=3 SV=2 CANONICAL=F1NVF2-1" }, "locus": { "chromosome": "18", "start_pos": 8648228, "end_pos": 8613222, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071189.1", "url": "https://www.ensembl.org/id/ENSGALT00010071189.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043880.1", "url": "https://www.ensembl.org/id/ENSGALP00010043880.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "gga:417445", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417445", "resource": "KEGG Pathway" }, { "id": "R-GGA-168638", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-168638", "resource": "Reactome", "description": "NOD1/2 Signaling Pathway" }, { "id": "R-GGA-2559580", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2559580", "resource": "Reactome", "description": "Oxidative Stress Induced Senescence" }, { "id": "R-GGA-450302", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-450302", "resource": "Reactome", "description": "activated TAK1 mediates p38 MAPK activation" }, { "id": "R-GGA-6811555", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6811555", "resource": "Reactome", "description": "PI5P Regulates TP53 Acetylation" }, { "id": "R-GGA-9020702", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9020702", "resource": "Reactome", "description": "Interleukin-1 signaling" }, { "id": "R-GGA-9833482", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9833482", "resource": "Reactome", "description": "PKR-mediated signaling" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "F1NVF2", "url": "https://www.uniprot.org/uniprotkb/F1NVF2" } ], "pmid": "" }, { "name": "protein tyrosine kinase activity", "id": "GO:0004713", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004713", "evidence": [ { "database": "UniProtKB", "id": "F1NVF2", "url": "https://www.uniprot.org/uniprotkb/F1NVF2" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "F1NVF2", "url": "https://www.uniprot.org/uniprotkb/F1NVF2" } ], "pmid": "" }, { "name": "protein kinase binding", "id": "GO:0019901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019901", "evidence": [ { "database": "UniProtKB", "id": "F1NVF2", "url": "https://www.uniprot.org/uniprotkb/F1NVF2" } ], "pmid": "" }, { "name": "MAP kinase kinase activity", "id": "GO:0004708", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004708", "evidence": [ { "database": "UniProtKB", "id": "F1NVF2", "url": "https://www.uniprot.org/uniprotkb/F1NVF2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "F1NVF2", "url": "https://www.uniprot.org/uniprotkb/F1NVF2" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F1NVF2", "url": "https://www.uniprot.org/uniprotkb/F1NVF2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 7, "go_terms": [ { "name": "MAPK cascade", "id": "GO:0000165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000165", "evidence": [ { "database": "UniProtKB", "id": "F1NVF2", "url": "https://www.uniprot.org/uniprotkb/F1NVF2" } ], "pmid": "" }, { "name": "bone development", "id": "GO:0060348", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060348", "evidence": [ { "database": "UniProtKB", "id": "F1NVF2", "url": "https://www.uniprot.org/uniprotkb/F1NVF2" } ], "pmid": "" }, { "name": "osteoblast differentiation", "id": "GO:0001649", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001649", "evidence": [ { "database": "UniProtKB", "id": "F1NVF2", "url": "https://www.uniprot.org/uniprotkb/F1NVF2" } ], "pmid": "" }, { "name": "stress-activated MAPK cascade", "id": "GO:0051403", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051403", "evidence": [ { "database": "UniProtKB", "id": "F1NVF2", "url": "https://www.uniprot.org/uniprotkb/F1NVF2" } ], "pmid": "" }, { "name": "p38MAPK cascade", "id": "GO:0038066", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038066", "evidence": [ { "database": "UniProtKB", "id": "F1NVF2", "url": "https://www.uniprot.org/uniprotkb/F1NVF2" } ], "pmid": "" }, { "name": "negative regulation of cold-induced thermogenesis", "id": "GO:0120163", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120163", "evidence": [ { "database": "UniProtKB", "id": "F1NVF2", "url": "https://www.uniprot.org/uniprotkb/F1NVF2" } ], "pmid": "" }, { "name": "regulation of intracellular signal transduction", "id": "GO:1902531", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902531", "evidence": [ { "database": "UniProtKB", "id": "F1NVF2", "url": "https://www.uniprot.org/uniprotkb/F1NVF2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "10596", "name": "", "equation": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V1ADF0-1", "F1N9Y5-1", "A0A8V0XQG0-1", "A0A8V0Y9A0-1", "A0A8V1AFM7-1", "A0A8V0Z0R8-1", "A0A8V0Z4B2-1", "A0A8V0ZBN6-1", "P09324-1", "A0A8V0XHW1-1", "A0A8V0YW12-1", "A0A8V0YUJ4-1", "A0A8V0ZSN8-1", "F1NVF2-1", "A0A8V1AKW4-1", "A0A8V0XB17-1", "A0A8V0ZC34-1", "A0A8V0YYC1-1", "A0A8V0ZND5-1", "A0A8V1ACF7-1", "A0A8V0ZP30-1", "E1BTE1-1", "Q07497-1", "A0A8V0X6E7-1", "F1NCL8-1", "A0A8V0XNF4-1", "A0A8V0XN86-1", "A0A8V0YEV0-1", "A0A8V0XQ80-1", "A0A8V0XZ82-1", "A0A8V0YZE5-1", "A0A8V0YYZ7-1", "A0A8V0YCV8-1", "A0A8V0YGR1-1", "A0A8V0YNY4-1", "A0A8V0YXM5-1", "A0A8V0YXZ9-1", "A0A3Q2UKD3-1", "A0A8V0YIT6-1", "A0A8V0YIV6-1", "R4GJW5-1", "A0A8V1A3N1-1", "A0A8V1A9R2-1", "A0A8V0ZE65-1", "A0A8V0ZER1-1", "A0A8V0ZXS7-1", "A0A8V1A7N1-1", "H9KZZ1-1", "F1NQL9-1", "A0A8V1ABP4-1", "F1NZY8-1", "Q02977-1", "A0A1D5PD64-1", "A0A8V0ZDU6-1", "A0A3Q2U1T2-1", "R4GJB8-1", "A0A3Q2U639-1", "A0A8V0X5W9-1", "E1C7Z1-1", "A0A8V0Y7Y3-1", "Q5ZIU3-1", "A0A8V0YPR4-1", "A0A8V0YT43-1", "A0A8V0Z3S3-1", "A0A8V0YJJ1-1", "A0A8V0YKP8-1", "A0A8V0YZ74-1", "A0A8V0ZWV8-1", "A0A8V1A069-1", "A0A8V1A7E0-1", "A0A8V1AEL3-1", "E1BTT3-1", "F1N996-1", "H9KZZ2-1", "E1C2C8-1", "Q05876-1", "Q90891-1", "O42422-1", "P00523-1", "P08941-1", "P13387-1", "P18460-1", "P18461-1", "P21804-1", "P28693-1", "P29318-1", "P42683-1", "P54755-1", "Q00944-1", "Q07494-1", "Q07496-1", "Q07498-1", "Q08156-1", "Q6XUX0-1", "Q75R65-1", "Q8AXY6-1", "Q8JH64-1", "Q8QHL3-1", "Q91009-1", "Q91044-1", "Q91987-1", "Q98949-1", "Q9PUF6-1", "F1NW21-1", "A0A8V0YLC3-1", "A0A8V0Z7L6-1", "F1NJX6-1", "A0A8V0YUC4-1", "F1NUX4-1", "A0A8V1A2E6-1", "E1BX69-1", "A0A8V0XPF0-1", "A0A8V0XFC9-1", "A0A8V0XBZ6-1", "A0A8V0ZRU7-1", 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"A0A8V0ZZE4-1", "P05625-1", "P13863-1", "P67962-1", "Q04982-2", "Q0GGW5-1", "Q6XUX0-1", "Q8QGX4-1", "Q9I9E0-1", "Q9IA88-1", "Q5ZJK4-1", "A0A1D5PTJ8-1", "E1C2I2-1", "F1NCX7-1", "F1NKW3-1", "A0A8V1A0W4-1", "A0A8V1A4J8-1", "A0A8V1ACK0-1", "F1NCY7-1", "A0A8V0X6T4-1", "A0A8V0ZFM2-1", "A0A8V0XUM6-1", "A0A8V0XEA3-1", "A0A8V1AIY7-1", "A0A8V0YHH2-1", "A0A3Q2UI52-1", "A0A8V0ZZK5-1", "A0A8V0ZPX2-1", "A0A8V1ACB5-1", "A0A8V0YDH4-1", "A0A8V1AFS4-1", "A0A8V1AH12-1", "A0A8V0YRC9-1", "A0A8V0ZQT5-1", "A0A8V0ZFP1-1", "E1C764-1", "A0A1D5PUY5-1", "F1P4G3-1", "A0A8V0ZMK1-1", "A0A8V0Y2I5-1", "A0A8V0ZLU3-1", "A0A8V0ZNP7-1", "A0A8V0Z2Z3-1", "A0A8V0YNI5-1", "Q90771-1", "A0A8V0X4P0-1", "A0A8V0X7R2-1", "A0A3Q3A664-1", "A0A8V0YGW2-1", "E1C581-1", "A0A8V1AC40-1", "A0A3Q2TUS7-1", "A0A1D5PA08-1", "A0A8V0XFW1-1", "A0A8V0XAH9-1", "A0A8V1A4A1-1", "A0A8V0ZD40-1", "A0A8V0Z6T1-1", "A0A8V1A4V7-1", "E1C093-1", "A0A8V0YZF2-1", "E1BX69-1", "A0A8V0XI18-1", "A0A8V0Y955-1", "A0A1D5PB73-1", "A0A1D5PV76-1", "A0A1D5PX90-1", "A0A1L1RWI9-1", "A0A3Q2TV19-1", "A0A3Q2UF44-1", "A0A8V0X4Q3-1", "A0A8V0Z124-1", "A0A8V0Z6K4-1", "A0A8V1AE45-1", "A0A8V0YZV9-1", "A0A8V0YYZ3-1", "A0A8V0ZUC6-1", "A0A8V0ZUU8-1", "A0A8V1AG70-1", "F1NA68-1", "F1NLR7-1", "A0A8V0Y6K1-1", "A0A8V0XS42-1", "A0A8V0YRN4-1", "A0A8V0YFP8-1", "A0A8V1A7P9-1", "A0A1D5PRN8-1", "A0A3Q3AAD7-1", "A0A3Q2TWZ8-1", "A0A8V0XBZ0-1", "A0A8V0XFX2-1", "A0A8V0YFL1-1", "A0A8V0YTL9-1", "A0A8V0YMB3-1", "A0A8V0X2Y2-1", "A0A8V0XCY6-1", "A0A3Q2UI62-1", "A0A8V0Y241-1", "A0A8V0Z8G2-1", "A0A8V1ABR8-1", "A0A8V1AP60-1", "A0A8V0YZM1-1", "A0A8V0ZB38-1", "A0A8V0Z466-1", "A0A8V0ZA06-1", "A0A8V1AMQ2-1", "A0A8V0ZGY3-1", "A0A8V0ZQJ2-1", "A0A8V0ZYU6-1", "A0A8V1A513-1", "A0A8V0XE48-1", "A0A8V0XQQ4-1", "A0A8V0XKG0-1" ], "evidence": [ { "id": "17989", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/17989" } ] }, { "id": "46608", "name": "", "equation": "L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A1D5PUY5-1", "Q6U1I9-1", "A0A8V0XNJ2-1", "A0A8V0ZUL0-1", "A0A8V0ZT63-1", "A0A8V1ACW2-1", "A0A8V0Z1X0-1", "A0A8V0YHN2-1", "A0A8V0YMN5-1", "A0A8V0Z807-1", "A0A8V0Z930-1", "A0A8V0YFR6-1", "A0A1D5P0M9-1", "A0A8V0ZBN6-1", "A0A3Q2U9U9-1", "A0A8V0YRC9-1", "A0A8V0YXZ5-1", "A0A8V0ZSP4-1", "A0A8V0ZXQ9-1", "A0A8V0ZZV3-1", "A0A8V1ADF0-1", "A0A8V0ZFT3-1", "A0A8V0ZA45-1", "A0A8V0ZB33-1", "A0A8V0ZD70-1", "A0A8V0Z8T4-1", "R4GIN8-1", "A0A8V0ZK64-1", "A0A8V0ZC16-1", "A0A8V0ZWW1-1", "E1BY69-1", "A0A8V0ZDW9-1", "A0A8V0ZKA2-1", "A0A3Q3B2F1-1", "F1P356-1", "A0A8V1AHA8-1", "Q8QFP8-1", "F1P011-1", "A0A8V0YKK3-1", "A0A1D5NWT4-1", "A0A1D5PMQ7-1", "E1BWA3-1", "F1NVF2-1", "A0A1D5PXN4-1", "A0A3Q2TY19-1", "A0A3Q2U592-1", "A0A8V0XCV5-1", "A0A1D5P8A9-1", "A0A1D5PMG2-1", "A0A8V0X1Q7-1", "A0A8V0Y935-1", "A0A8V0YM96-1", "A0A8V0YF83-1", "A0A8V0YJP9-1", "A0A8V1AKW4-1", "A0A1D5P517-1", "A0A8V0ZSB4-1", "F1NBT0-1", "P18652-1", "P21868-1", "P21869-1", "P53666-1", "P79996-1", "Q5F3W3-1", "Q5ZJS0-1", "Q5ZKN1-1", "Q5ZLL1-1", "A0A8V0XCS0-1", "A0A8V0XNK8-1", "A0A8V0XLV6-1", "A0A8V0XDR5-1", "E1BYH2-1", "F1NB57-1", "E1BQN6-1", "A0A8V0XU71-1", "Q5ZJH6-1", "A0A8V0Y3D1-1", "A0A8V0Y7C3-1", "A0A8V0YCY4-1", "A0A8V0YIV6-1", "A0A8V0YK18-1", "A0A8V0YM22-1", "A0A8V0YTN5-1", "A0A8V0YTP2-1", "Q5F3L1-1", "A0A8V0XU96-1", "E1C6T4-1", "A0A8V0Y3L2-1", "A0A8V0YCY8-1", "A0A8V0Y9Q1-1", "A0A8V0ZD48-1", "A0A8V0ZD60-1", "A0A8V0ZBZ2-1", "A0A8V0Z9J0-1", "A0A8V1ABF3-1", "Q8AYC9-1", "A0A8V0Z927-1", "A0A8V1A2T9-1", "Q5ZKI0-1", "Q7T0B1-1", "P10741-1", "A0A8V1AMK5-1", "P67962-1", "A0A8V0YFH4-1", "E1C848-1", "A0A8V0X8M1-1", "E1BW33-1", "A0A8V0Z283-1", "A0A8V0Z157-1", "A0A3Q2U4X3-1", "A0A8V0XW11-1", "E1BUG0-1", "A0A8V1ABP4-1", "A0A8V1AJA4-1", "A0A8V1AEH4-1", "F1NJH1-1", "A0A3Q2TRY2-1", "A0A8V0X3D6-1", "A0A1D5PD64-1", "A0A8V0XQ97-1", "R4GJB8-1", "A0A8V0X5Z8-1", "A0A8V0XG21-1", "A0A8V0XB58-1", "A0A8V0XMX8-1", "A0A8V0XQS0-1", "A0A8V0XW29-1", "A0A8V0Y074-1", "A0A8V0XXB8-1", "A0A8V0XQ14-1", "A0A8V0XI18-1", "A0A8V0XMT1-1", "A0A8V0Y457-1", "A0A8V0Y823-1", "A0A8V0Y4L8-1", "A0A8V0XND6-1", "A0A8V0Y8X9-1", "A0A8V0YZ74-1", "A0A8V0YTI1-1", "A0A8V0YLV1-1", "A0A8V0Z2E3-1", "A0A8V0YCV9-1", "A0A8V0YSH3-1", "A0A8V0YYX2-1", "A0A8V0YZY4-1", "Q5ZIU3-1", "A0A8V0YZK0-1", "A0A8V0ZKM9-1", "A0A8V0ZWC7-1", "A0A8V1A1Y7-1", "A0A8V1A069-1", "A0A8V0ZI32-1", "A0A8V0ZH91-1", "E1BQV7-1", "A0A8V0ZRX1-1", "A0A8V0ZUU9-1", "A0A8V1A0Y8-1", "A0A8V1A7E9-1", "A0A8V1A7E0-1", "A0A8V1A3T8-1", "A0A8V1A9S5-1", "A0A8V1A7M0-1", "A0A8V1A675-1", "A0A8V1A1P3-1", "A0A8V1ADT4-1", "E1BWT0-1", "A0A8V1ACF6-1", "A0A8V1ADN9-1", "A0A8V1AM12-1", "A0A8V1A4Q4-1", "Q90891-1", "F1NUX4-1", "A0A8V0ZZE4-1", "P05625-1", "P13863-1", "Q04982-2", "Q0GGW5-1", "Q6XUX0-1", "Q8QGX4-1", "Q9I9E0-1", "Q9IA88-1", "Q5ZJK4-1", "A0A1D5PTJ8-1", "E1C2I2-1", "F1NCX7-1", "F1NKW3-1", "A0A8V1A0W4-1", "A0A8V1A4J8-1", "A0A8V1ACK0-1", "F1NCY7-1", "A0A8V0X6T4-1", "A0A8V0XUM6-1", "A0A8V0XEA3-1", "A0A8V0YHH2-1", "A0A3Q2UI52-1", "A0A8V0ZZK5-1", "A0A8V0ZPX2-1", "A0A8V1ACB5-1", "A0A8V0YDH4-1", "A0A8V1AFS4-1", "A0A8V1AH12-1", "A0A8V0ZQT5-1", "A0A8V0ZFP1-1", "E1C764-1", "F1P4G3-1", "A0A8V0Y2I5-1", "A0A8V0ZLU3-1", "A0A8V0ZNP7-1", "A0A8V0Z2Z3-1", "A0A8V0YNI5-1", "Q90771-1", "A0A8V0X4P0-1", "A0A8V0X7R2-1", "A0A3Q3A664-1", "A0A8V0YGW2-1", "E1C581-1", "A0A8V1AC40-1", "A0A3Q2TUS7-1", "A0A1D5PA08-1", "A0A8V0XFW1-1", "A0A8V0XAH9-1", "A0A8V0ZFM2-1", "A0A8V1A4A1-1", "A0A8V0ZD40-1", "A0A8V0Z6T1-1", "A0A8V1A4V7-1", "A0A8V0YZF2-1", "E1BX69-1", "A0A8V0Y955-1", "A0A1D5PB73-1", "A0A1D5PV76-1", "A0A1D5PX90-1", "A0A1L1RWI9-1", "A0A3Q2TV19-1", "A0A3Q2UF44-1", "A0A8V0X4Q3-1", "A0A8V0Z124-1", "A0A8V0Z6K4-1", "A0A8V1AIY7-1", "A0A8V1AE45-1", "A0A8V0YZV9-1", "A0A8V0YYZ3-1", "A0A8V0ZUC6-1", "A0A8V0ZUU8-1", "A0A8V1AG70-1", "F1NA68-1", "F1NLR7-1", "A0A8V0Y6K1-1", "A0A8V0XS42-1", "A0A8V0YRN4-1", "A0A8V0YFP8-1", "A0A8V1A7P9-1", "A0A1D5PRN8-1", "A0A3Q3AAD7-1", "A0A3Q2TWZ8-1", "A0A8V0XBZ0-1", "A0A8V0XFX2-1", "A0A8V0YFL1-1", "A0A8V0YTL9-1", "A0A8V0YMB3-1", "A0A8V0X2Y2-1", "A0A8V0XCY6-1", "A0A3Q2UI62-1", "A0A8V0Y241-1", "A0A8V0Z8G2-1", "A0A8V1ABR8-1", "A0A8V1AP60-1", "A0A8V0YZM1-1", "A0A8V0ZB38-1", "A0A8V0Z466-1", "A0A8V0ZA06-1", "A0A8V1AMQ2-1", "A0A8V0ZGY3-1", "A0A8V0ZQJ2-1", "A0A8V0ZYU6-1", "A0A8V1A513-1", "A0A8V0XE48-1", "A0A8V0XKG0-1" ], "evidence": [ { "id": "46608", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/46608" } ] }, { "id": "R-GGA-3228469", "name": "MAP3K5 phosphorylates MKK3 and MKK6", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1NVF2-1", "A0A1D5PTJ8-1", "A0A1D5PD64-1" ], "evidence": [ { "id": "R-GGA-3228469", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3228469" } ] }, { "id": "R-GGA-3238999", "name": "Activated human MKK3/MKK6 phosphorylates p38 MAPK complexed with MAPKAPK5", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1NVF2-1", "A0A1D5PD64-1", "A0A8V1A4J8-1", "A0A1D5PIQ5-1" ], "evidence": [ { "id": "R-GGA-3238999", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3238999" } ] }, { "id": "R-GGA-450296", "name": "Phosphorylated MKK3/MKK6 migrates to nucleus", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1NVF2-1", "A0A1D5PD64-1" ], "evidence": [ { "id": "R-GGA-450296", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-450296" } ] }, { "id": "R-GGA-450333", "name": "Activated human MKK3/MKK6 phosphorylates p38 MAPK complexed with MAPKAPK2 or MAPKAPK3", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1NVF2-1", "A0A1D5PD64-1", "F1NCY7-1", "A0A1D5PIQ5-1" ], "evidence": [ { "id": "R-GGA-450333", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-450333" } ] }, { "id": "R-GGA-450346", "name": "activated human TAK1 phosphorylates MKK3/MKK6", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1NVF2-1", "A0A1D5PD64-1", "A0A8V0XCV5-1", "E1C626-1" ], "evidence": [ { "id": "R-GGA-450346", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-450346" } ] }, { "id": "R-GGA-727819", "name": "TAK1 phosphorylates MKK6", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [ "R-GGA-167998" ], "output_participant_list": [ "R-GGA-206255" ], "enzyme_list": [ "F1NVF2-1", "A0A8V0XCV5-1" ], "evidence": [ { "id": "R-GGA-727819", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-727819" } ] }, { "id": "R-GGA-8877691", "name": "MAP2K6 phosphorylates PIP4K2B", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1NVF2-1", "A0A8V0ZGK7-1", "A0A8V0ZWL6-1", "A0A8V0XM27-1" ], "evidence": [ { "id": "R-GGA-8877691", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8877691" } ] }, { "id": "R-GGA-9836322", "name": "p-PKR dimer phosphorylates MKK6", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1NVF2-1" ], "evidence": [ { "id": "R-GGA-9836322", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9836322" } ] } ], "reaction_participants": [ { "participant_id": "R-GGA-167998", "participant_name": "MAP2K6 [cytosol]", "crossref": [ { "id": "A0A1D5PHN6", "database": "UniProt", "url": "" }, { "id": "ENSGALG00010029424", "database": "ENSEMBL", "url": "" }, { "id": "ENSGALP00010043878", "database": "ENSEMBL", "url": "" }, { "id": "ENSGALT00010071187", "database": "ENSEMBL", "url": "" }, { "id": "XP_004946297.1", "database": "RefSeq", "url": "" }, { "id": "XP_040542427.1", "database": "RefSeq", "url": "" } ] }, { "participant_id": "R-GGA-206255", "participant_name": "phospho-MAP2K6 [cytosol]", "crossref": [ { "id": "ENSGALT00010071187", "database": "ENSEMBL", "url": "" }, { "id": "XP_040542427.1", "database": "RefSeq", "url": "" }, { "id": "ENSGALG00010029424", "database": "ENSEMBL", "url": "" }, { "id": "A0A1D5PHN6", "database": "UniProt", "url": "" }, { "id": "ENSGALP00010043878", "database": "ENSEMBL", "url": "" }, { "id": "XP_004946297.1", "database": "RefSeq", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A0A1D5NWT4", "gene_name": "RPS6KA3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5NWT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NWT4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A1D5NWT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NWT4" } ] } ] }, { "uniprot_ac": "A0A1D5P0M9", "gene_name": "MAP3K13", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { 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ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q3B2F1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3B2F1" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A3Q3B2F1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3B2F1" } ] } ] }, { "uniprot_ac": "A0A8V0X1Q7", "gene_name": "MELK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X1Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X1Q7" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X1Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X1Q7" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0X1Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X1Q7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0X1Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X1Q7" } ] } ] }, { "uniprot_ac": "A0A8V0X2Y2", "gene_name": "MAPK12", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X2Y2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X2Y2" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0X2Y2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X2Y2" } ] } ] }, { "uniprot_ac": "A0A8V0X3D6", "gene_name": "LOC100858386", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X3D6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X3D6" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0X3D6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X3D6" } ] } ] }, { "uniprot_ac": "A0A8V0X4P0", "gene_name": "CDKL5", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X4P0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X4P0" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0X4P0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X4P0" } ] } ] }, { "uniprot_ac": "A0A8V0X4Q3", "gene_name": "ICK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X4Q3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X4Q3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0X4Q3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X4Q3" } ] } ] }, { "uniprot_ac": "A0A8V0X5W9", "gene_name": "TYK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X5W9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X5W9" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0X5W9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X5W9" } ] } ] }, { "uniprot_ac": "A0A8V0X5Z8", "gene_name": "NEK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X5Z8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X5Z8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0X5Z8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X5Z8" } ] } ] }, { "uniprot_ac": "A0A8V0X6E7", "gene_name": "FES", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X6E7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X6E7" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0X6E7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X6E7" } ] } ] }, { "uniprot_ac": "A0A8V0X6T4", "gene_name": "LOC107050692", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X6T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X6T4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0X6T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X6T4" } ] } ] }, { "uniprot_ac": "A0A8V0X7R2", "gene_name": "SBK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X7R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X7R2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0X7R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X7R2" } ] } ] }, { "uniprot_ac": "A0A8V0X8M1", "gene_name": "TRIO", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X8M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X8M1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0X8M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X8M1" } ] } ] }, { "uniprot_ac": "A0A8V0XAH9", "gene_name": "NEK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XAH9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XAH9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XAH9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XAH9" } ] } ] }, { "uniprot_ac": "A0A8V0XB17", "gene_name": "FGFR2", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XB17", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XB17" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0XB17", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XB17" } ] } ] }, { "uniprot_ac": "A0A8V0XB58", "gene_name": "CAMK2D", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XB58", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XB58" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V0XB58", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XB58" } ] } ] }, { "uniprot_ac": "A0A8V0XBZ0", "gene_name": "STK32C", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XBZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XBZ0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XBZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XBZ0" } ] } ] }, { "uniprot_ac": "A0A8V0XBZ6", "gene_name": "EPHA7", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XBZ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XBZ6" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0XBZ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XBZ6" } ] } ] }, { "uniprot_ac": "A0A8V0XCS0", "gene_name": "PRKG2", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XCS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCS0" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "A0A8V0XCS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCS0" } ] } ] }, { "uniprot_ac": "A0A8V0XCV5", "gene_name": "MAP3K7", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XCV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCV5" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0XCV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCV5" } ] } ] }, { "uniprot_ac": "A0A8V0XCY6", "gene_name": "TTK", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XCY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCY6" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V0XCY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCY6" } ] } ] }, { "uniprot_ac": "A0A8V0XDR5", "gene_name": "IRAK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XDR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XDR5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XDR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XDR5" } ] } ] }, { "uniprot_ac": "A0A8V0XE48", "gene_name": "ROCK2", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XE48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XE48" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "A0A8V0XE48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XE48" } ] } ] }, { "uniprot_ac": "A0A8V0XEA3", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XEA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEA3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XEA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEA3" } ] } ] }, { "uniprot_ac": "A0A8V0XFC9", "gene_name": "EPHA5", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XFC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XFC9" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0XFC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XFC9" } ] } ] }, { "uniprot_ac": "A0A8V0XFW1", "gene_name": "SGK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XFW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XFW1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XFW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XFW1" } ] } ] }, { "uniprot_ac": "A0A8V0XFX2", "gene_name": "NEK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XFX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XFX2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XFX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XFX2" } ] } ] }, { "uniprot_ac": "A0A8V0XG21", "gene_name": "LOC107050335", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XG21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XG21" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XG21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XG21" } ] } ] }, { "uniprot_ac": "A0A8V0XHW1", "gene_name": "LYN", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XHW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XHW1" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0XHW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XHW1" } ] } ] }, { "uniprot_ac": "A0A8V0XI18", "gene_name": "ATM", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XI18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XI18" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XI18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XI18" } ] } ] }, { "uniprot_ac": "A0A8V0XKG0", "gene_name": "NEK9", "activity": [ { "ec_number": "2.7.11.38", "activity": "L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XKG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XKG0" } ] }, { "ec_number": "2.7.11.38", "activity": "", "evidence": [ { "id": "A0A8V0XKG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XKG0" } ] } ] }, { "uniprot_ac": "A0A8V0XLV6", "gene_name": "MAPK10", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XLV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XLV6" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0XLV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XLV6" } ] } ] }, { "uniprot_ac": "A0A8V0XM27", "gene_name": "PIP4K2A", "activity": [ { "ec_number": "2.7.1.149", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-5-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0A8V0XM27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XM27" } ] }, { "ec_number": "2.7.1.149", "activity": "", "evidence": [ { "id": "A0A8V0XM27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XM27" } ] } ] }, { "uniprot_ac": "A0A8V0XMT1", "gene_name": "MOS", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XMT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMT1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XMT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMT1" } ] } ] }, { "uniprot_ac": "A0A8V0XMX8", "gene_name": "MASTL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XMX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMX8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XMX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMX8" } ] } ] }, { "uniprot_ac": "A0A8V0XN86", "gene_name": "MUSK", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XN86", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XN86" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0XN86", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XN86" } ] } ] }, { "uniprot_ac": "A0A8V0XND6", "gene_name": "RIOK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XND6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XND6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XND6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XND6" } ] } ] }, { "uniprot_ac": "A0A8V0XNF4", "gene_name": "EGFR", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XNF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNF4" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0XNF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNF4" } ] } ] }, { "uniprot_ac": "A0A8V0XNJ2", "gene_name": "CDK8", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XNJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNJ2" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XNJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNJ2" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0XNJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNJ2" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A8V0XNJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNJ2" } ] } ] }, { "uniprot_ac": "A0A8V0XNK8", "gene_name": "PRKCQ", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XNK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNK8" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V0XNK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNK8" } ] } ] }, { "uniprot_ac": "A0A8V0XPF0", "gene_name": "EPHA6", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XPF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XPF0" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0XPF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XPF0" } ] } ] }, { "uniprot_ac": "A0A8V0XQ14", "gene_name": "PLK4", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XQ14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ14" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0A8V0XQ14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ14" } ] } ] }, { "uniprot_ac": "A0A8V0XQ80", "gene_name": "FLT3", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XQ80", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ80" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0XQ80", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ80" } ] } ] }, { "uniprot_ac": "A0A8V0XQ97", "gene_name": "CDK14", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XQ97", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ97" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0XQ97", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ97" } ] } ] }, { "uniprot_ac": "A0A8V0XQG0", "gene_name": "FLT1", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XQG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQG0" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0XQG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQG0" } ] } ] }, { "uniprot_ac": "A0A8V0XQQ4", "gene_name": "NME7", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQQ4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQQ4" } ] } ] }, { "uniprot_ac": "A0A8V0XQS0", "gene_name": "STK24", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XQS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQS0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XQS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQS0" } ] } ] }, { "uniprot_ac": "A0A8V0XS42", "gene_name": "MAP3K4", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XS42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XS42" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0XS42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XS42" } ] } ] }, { "uniprot_ac": "A0A8V0XU71", "gene_name": "MYO3A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XU71", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XU71" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XU71", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XU71" } ] } ] }, { "uniprot_ac": "A0A8V0XU96", "gene_name": "PRKD1", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XU96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XU96" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V0XU96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XU96" } ] } ] }, { "uniprot_ac": "A0A8V0XUM6", "gene_name": "LATS1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XUM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XUM6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XUM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XUM6" } ] } ] }, { "uniprot_ac": "A0A8V0XW11", "gene_name": "RPS6KA2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XW11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XW11" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XW11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XW11" } ] } ] }, { "uniprot_ac": "A0A8V0XW29", "gene_name": "CDKL2", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XW29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XW29" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0XW29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XW29" } ] } ] }, { "uniprot_ac": "A0A8V0XXB8", "gene_name": "MAPK15", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XXB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XXB8" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0XXB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XXB8" } ] } ] }, { "uniprot_ac": "A0A8V0XZ82", "gene_name": "PTK2B", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XZ82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XZ82" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0XZ82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XZ82" } ] } ] }, { "uniprot_ac": "A0A8V0Y074", "gene_name": "NEK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y074", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y074" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y074", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y074" } ] } ] }, { "uniprot_ac": "A0A8V0Y241", "gene_name": "LOC426385", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y241", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y241" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y241", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y241" } ] } ] }, { "uniprot_ac": "A0A8V0Y2I5", "gene_name": "CDK7", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] }, { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] } ] }, { "uniprot_ac": "A0A8V0Y3D1", "gene_name": "LRRK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y3D1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y3D1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y3D1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y3D1" } ] } ] }, { "uniprot_ac": "A0A8V0Y3L2", "gene_name": "MLK4", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y3L2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y3L2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0Y3L2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y3L2" } ] } ] }, { "uniprot_ac": "A0A8V0Y457", "gene_name": "PRPF4B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y457", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y457" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y457", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y457" } ] } ] }, { "uniprot_ac": "A0A8V0Y4L8", "gene_name": "HUNK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y4L8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y4L8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y4L8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y4L8" } ] } ] }, { "uniprot_ac": "A0A8V0Y6K1", "gene_name": "MAK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y6K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y6K1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y6K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y6K1" } ] } ] }, { "uniprot_ac": "A0A8V0Y7C3", "gene_name": "DAPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y7C3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y7C3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y7C3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y7C3" } ] } ] }, { "uniprot_ac": "A0A8V0Y7Y3", "gene_name": "ABL2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y7Y3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y7Y3" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0Y7Y3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y7Y3" } ] } ] }, { "uniprot_ac": "A0A8V0Y823", "gene_name": "SRPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y823", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y823" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y823", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y823" } ] } ] }, { "uniprot_ac": "A0A8V0Y8X9", "gene_name": "PRKACA", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y8X9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y8X9" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "A0A8V0Y8X9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y8X9" } ] } ] }, { "uniprot_ac": "A0A8V0Y935", "gene_name": "MAST4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y935", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y935" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y935", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y935" } ] } ] }, { "uniprot_ac": "A0A8V0Y955", "gene_name": "PAK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y955", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y955" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y955", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y955" } ] } ] }, { "uniprot_ac": "A0A8V0Y9A0", "gene_name": "PTK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y9A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9A0" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0Y9A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9A0" } ] } ] }, { "uniprot_ac": "A0A8V0Y9Q1", "gene_name": "LOC107055388", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y9Q1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9Q1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y9Q1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9Q1" } ] } ] }, { "uniprot_ac": "A0A8V0YCV8", "gene_name": "NTRK2", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YCV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCV8" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0YCV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCV8" } ] } ] }, { "uniprot_ac": "A0A8V0YCV9", "gene_name": "SIK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YCV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCV9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YCV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCV9" } ] } ] }, { "uniprot_ac": "A0A8V0YCY4", "gene_name": "AURKB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YCY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCY4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YCY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCY4" } ] } ] }, { "uniprot_ac": "A0A8V0YCY8", "gene_name": "RIOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YCY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCY8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YCY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCY8" } ] } ] }, { "uniprot_ac": "A0A8V0YDH4", "gene_name": "ALPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YDH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDH4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YDH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDH4" } ] } ] }, { "uniprot_ac": "A0A8V0YEV0", "gene_name": "WEE2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YEV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEV0" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0YEV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEV0" } ] } ] }, { "uniprot_ac": "A0A8V0YF83", "gene_name": "WNK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YF83", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF83" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YF83", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF83" } ] } ] }, { "uniprot_ac": "A0A8V0YFH4", "gene_name": "NRK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YFH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFH4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YFH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFH4" } ] } ] }, { "uniprot_ac": "A0A8V0YFL1", "gene_name": "CDK19", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YFL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFL1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0YFL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFL1" } ] } ] }, { "uniprot_ac": "A0A8V0YFP8", "gene_name": "RIPK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YFP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFP8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YFP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFP8" } ] } ] }, { "uniprot_ac": "A0A8V0YFR6", "gene_name": "TNIK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YFR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFR6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YFR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFR6" } ] } ] }, { "uniprot_ac": "A0A8V0YGR1", "gene_name": "RET", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YGR1", "database": "UniProtKB", "url": 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"ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YHH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHH2" } ] } ] }, { "uniprot_ac": "A0A8V0YHN2", "gene_name": "RPS6KA1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YHN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHN2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YHN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHN2" } ] } ] }, { "uniprot_ac": "A0A8V0YIT6", "gene_name": "ERBB4", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YIT6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIT6" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0YIT6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIT6" } ] } ] }, { "uniprot_ac": "A0A8V0YIV6", "gene_name": "DYRK1A", "activity": [ { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] }, { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] } ] }, { "uniprot_ac": "A0A8V0YJJ1", "gene_name": "ITK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YJJ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJJ1" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0YJJ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJJ1" } ] } ] }, { "uniprot_ac": "A0A8V0YJP9", "gene_name": "RIOK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YJP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJP9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YJP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJP9" } ] } ] }, { "uniprot_ac": "A0A8V0YK18", "gene_name": "CDC42BPB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YK18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK18" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YK18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK18" } ] } ] }, { "uniprot_ac": "A0A8V0YKK3", "gene_name": "MAP4K4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YKK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKK3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YKK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKK3" } ] } ] }, { "uniprot_ac": "A0A8V0YKP8", "gene_name": "VEGFRKDRL", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YKP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKP8" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0YKP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKP8" } ] } ] }, { "uniprot_ac": "A0A8V0YLC3", "gene_name": "PDGFRA", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YLC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLC3" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0YLC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLC3" } ] } ] }, { "uniprot_ac": "A0A8V0YLV1", "gene_name": "MARK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YLV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLV1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YLV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLV1" } ] } ] }, { "uniprot_ac": "A0A8V0YM22", "gene_name": "MYO3AL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YM22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM22" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YM22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM22" } ] } ] }, { "uniprot_ac": "A0A8V0YM96", "gene_name": "STK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YM96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM96" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YM96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM96" } ] } ] }, { "uniprot_ac": "A0A8V0YMB3", "gene_name": "STK32A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YMB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMB3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YMB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMB3" } ] } ] }, { "uniprot_ac": "A0A8V0YMN5", "gene_name": "BRAF", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YMN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMN5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YMN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMN5" } ] } ] }, { "uniprot_ac": "A0A8V0YNI5", "gene_name": "NIM1K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YNI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNI5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YNI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNI5" } ] } ] }, { "uniprot_ac": "A0A8V0YNY4", "gene_name": "JAK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YNY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNY4" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0YNY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNY4" } ] } ] }, { "uniprot_ac": "A0A8V0YPR4", "gene_name": "DDR2", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YPR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPR4" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0YPR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPR4" } ] } ] }, { "uniprot_ac": "A0A8V0YRC9", "gene_name": "TNK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YRC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRC9" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YRC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRC9" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0YRC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRC9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YRC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRC9" } ] } ] }, { "uniprot_ac": "A0A8V0YRJ8", "gene_name": "EPHA10", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YRJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRJ8" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0YRJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRJ8" } ] } ] }, { "uniprot_ac": "A0A8V0YRN4", "gene_name": "GAK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YRN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRN4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YRN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRN4" } ] } ] }, { "uniprot_ac": "A0A8V0YSH3", "gene_name": "RPS6KA6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YSH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSH3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YSH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSH3" } ] } ] }, { "uniprot_ac": "A0A8V0YT43", "gene_name": "HCK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YT43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YT43" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0YT43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YT43" } ] } ] }, { "uniprot_ac": "A0A8V0YTI1", "gene_name": "TSSK6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTI1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTI1" } ] } ] }, { "uniprot_ac": "A0A8V0YTL9", "gene_name": "VRK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTL9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTL9" } ] } ] }, { "uniprot_ac": "A0A8V0YTN5", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTN5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTN5" } ] } ] }, { "uniprot_ac": "A0A8V0YTP2", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTP2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTP2" } ] } ] }, { "uniprot_ac": "A0A8V0YUC4", "gene_name": "EPHB3", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YUC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUC4" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0YUC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUC4" } ] } ] }, { "uniprot_ac": "A0A8V0YUJ4", "gene_name": "BTK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YUJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUJ4" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0YUJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUJ4" } ] } ] }, { "uniprot_ac": "A0A8V0YW12", "gene_name": "FRK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YW12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YW12" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0YW12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YW12" } ] } ] }, { "uniprot_ac": "A0A8V0YWW2", "gene_name": "EPHA2", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YWW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YWW2" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0YWW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YWW2" } ] } ] }, { "uniprot_ac": "A0A8V0YXM5", "gene_name": "CSF1R", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YXM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXM5" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0YXM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXM5" } ] } ] }, { "uniprot_ac": "A0A8V0YXZ5", "gene_name": "CDC42BPA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YXZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXZ5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YXZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXZ5" } ] } ] }, { "uniprot_ac": "A0A8V0YXZ9", "gene_name": "FLT4", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YXZ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXZ9" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0YXZ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXZ9" } ] } ] }, { "uniprot_ac": "A0A8V0YYC1", "gene_name": "TXK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YYC1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYC1" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0YYC1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYC1" } ] } ] }, { "uniprot_ac": "A0A8V0YYI3", "gene_name": "EPHA8", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YYI3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYI3" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0YYI3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYI3" } ] } ] }, { "uniprot_ac": "A0A8V0YYX2", "gene_name": "PAK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YYX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYX2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YYX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYX2" } ] } ] }, { "uniprot_ac": "A0A8V0YYZ3", "gene_name": "SPEG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YYZ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYZ3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YYZ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYZ3" } ] } ] }, { "uniprot_ac": "A0A8V0YYZ7", "gene_name": "FGFR3", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YYZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYZ7" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0YYZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYZ7" } ] } ] }, { "uniprot_ac": "A0A8V0YZ74", "gene_name": "MAP2K5", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZ74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZ74" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V0YZ74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZ74" } ] } ] }, { "uniprot_ac": "A0A8V0YZE5", "gene_name": "PDGFRB", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZE5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZE5" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0YZE5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZE5" } ] } ] }, { "uniprot_ac": "A0A8V0YZF2", "gene_name": "PAK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZF2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YZF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZF2" } ] } ] }, { "uniprot_ac": "A0A8V0YZK0", "gene_name": "MAP3K6", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZK0" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0YZK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZK0" } ] } ] }, { "uniprot_ac": "A0A8V0YZM1", "gene_name": "MOK", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZM1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0YZM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZM1" } ] }, { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZM1" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0YZM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZM1" } ] } ] }, { "uniprot_ac": "A0A8V0YZP9", "gene_name": "EPHB2", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZP9" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0YZP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZP9" } ] } ] }, { "uniprot_ac": "A0A8V0YZV9", "gene_name": "ATR", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZV9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YZV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZV9" } ] } ] }, { "uniprot_ac": "A0A8V0YZY4", "gene_name": "SBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZY4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YZY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZY4" } ] } ] }, { "uniprot_ac": "A0A8V0Z0R8", "gene_name": "LCK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z0R8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z0R8" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0Z0R8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z0R8" } ] } ] }, { "uniprot_ac": "A0A8V0Z124", "gene_name": "VRK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z124", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z124" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z124", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z124" } ] } ] }, { "uniprot_ac": "A0A8V0Z157", "gene_name": "MARK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z157", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z157" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z157", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z157" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A8V0Z157", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z157" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z157", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z157" } ] } ] }, { "uniprot_ac": "A0A8V0Z189", "gene_name": "PKDCCA", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z189", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z189" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0Z189", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z189" } ] } ] }, { "uniprot_ac": "A0A8V0Z1X0", "gene_name": "MAP4K3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z1X0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1X0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z1X0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1X0" } ] } ] }, { "uniprot_ac": "A0A8V0Z283", "gene_name": "MARK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z283", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z283" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z283", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z283" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A8V0Z283", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z283" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z283", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z283" } ] } ] }, { "uniprot_ac": "A0A8V0Z2E3", "gene_name": "PDIK1L", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z2E3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2E3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z2E3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2E3" } ] } ] }, { "uniprot_ac": "A0A8V0Z2Z3", "gene_name": "AAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z2Z3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2Z3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z2Z3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2Z3" } ] } ] }, { "uniprot_ac": "A0A8V0Z3S3", "gene_name": "ALK", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z3S3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3S3" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0Z3S3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3S3" } ] } ] }, { "uniprot_ac": "A0A8V0Z466", "gene_name": "MAP3K19", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z466", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z466" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z466", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z466" } ] } ] }, { "uniprot_ac": "A0A8V0Z4B2", "gene_name": "MERTK", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z4B2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4B2" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0Z4B2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4B2" } ] } ] }, { "uniprot_ac": "A0A8V0Z6K4", "gene_name": "PIK3R4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z6K4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6K4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z6K4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6K4" } ] } ] }, { "uniprot_ac": "A0A8V0Z6T1", "gene_name": "ERN2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z6T1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6T1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z6T1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6T1" } ] } ] }, { "uniprot_ac": "A0A8V0Z7L6", "gene_name": "FGFR1", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z7L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7L6" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0Z7L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7L6" } ] } ] }, { "uniprot_ac": "A0A8V0Z807", "gene_name": "NEK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z807", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z807" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z807", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z807" } ] } ] }, { "uniprot_ac": "A0A8V0Z8G2", "gene_name": "TTBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z8G2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8G2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z8G2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8G2" } ] } ] }, { "uniprot_ac": "A0A8V0Z8T4", "gene_name": "RPS6KC1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z8T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8T4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z8T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8T4" } ] } ] }, { "uniprot_ac": "A0A8V0Z927", "gene_name": "PINK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z927", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z927" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z927", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z927" } ] } ] }, { "uniprot_ac": "A0A8V0Z930", "gene_name": "CAMK2B", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z930", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z930" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V0Z930", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z930" } ] } ] }, { "uniprot_ac": "A0A8V0Z9J0", "gene_name": "CIT", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z9J0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9J0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z9J0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9J0" } ] } ] }, { "uniprot_ac": "A0A8V0ZA06", "gene_name": "CDKL1", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZA06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA06" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0ZA06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA06" } ] } ] }, { "uniprot_ac": "A0A8V0ZA45", "gene_name": "MAP4K5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZA45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA45" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZA45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA45" } ] } ] }, { "uniprot_ac": "A0A8V0ZB33", "gene_name": "CAMK2G", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZB33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB33" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V0ZB33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB33" } ] } ] }, { "uniprot_ac": "A0A8V0ZB38", "gene_name": "CIITA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZB38", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB38" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZB38", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB38" } ] } ] }, { "uniprot_ac": "A0A8V0ZBN6", "gene_name": "MAP2K1", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZBN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBN6" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V0ZBN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBN6" } ] } ] }, { "uniprot_ac": "A0A8V0ZBZ2", "gene_name": "MAP3K9", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZBZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBZ2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0ZBZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBZ2" } ] } ] }, { "uniprot_ac": "A0A8V0ZC16", "gene_name": "KALRN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZC16", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC16" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZC16", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC16" } ] } ] }, { "uniprot_ac": "A0A8V0ZC34", "gene_name": "AXL", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZC34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC34" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0ZC34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC34" } ] } ] }, { "uniprot_ac": "A0A8V0ZD40", "gene_name": "CDC2L1", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD40" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD40" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A8V0ZD40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD40" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0ZD40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD40" } ] } ] }, { "uniprot_ac": "A0A8V0ZD48", "gene_name": "PRKCE", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD48" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V0ZD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD48" } ] } ] }, { "uniprot_ac": "A0A8V0ZD60", "gene_name": "STK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD60" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZD60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD60" } ] } ] }, { "uniprot_ac": "A0A8V0ZD70", "gene_name": "DCLK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD70" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZD70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD70" } ] } ] }, { "uniprot_ac": "A0A8V0ZDU6", "gene_name": "SRC", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZDU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDU6" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0ZDU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDU6" } ] } ] }, { "uniprot_ac": "A0A8V0ZDW9", "gene_name": "NEK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZDW9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDW9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZDW9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDW9" } ] } ] }, { "uniprot_ac": "A0A8V0ZE65", "gene_name": "NTRK3", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZE65", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE65" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0ZE65", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE65" } ] } ] }, { "uniprot_ac": "A0A8V0ZER1", "gene_name": "IGF1R", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZER1", "database": 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} ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZFP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFP1" } ] } ] }, { "uniprot_ac": "A0A8V0ZFT3", "gene_name": "LRRK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZFT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFT3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZFT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFT3" } ] } ] }, { "uniprot_ac": "A0A8V0ZGK7", "gene_name": "PIP4K2B", "activity": [ { "ec_number": "2.7.1.149", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-5-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZGK7", "database": "UniProtKB", "url": 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"ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZH91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH91" } ] } ] }, { "uniprot_ac": "A0A8V0ZI32", "gene_name": "STK16", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZI32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI32" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZI32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI32" } ] } ] }, { "uniprot_ac": "A0A8V0ZK64", "gene_name": "PDPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZK64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK64" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": 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1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,5-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZMK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMK1" } ] }, { "ec_number": "2.7.1.150", "activity": "", "evidence": [ { "id": "A0A8V0ZMK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMK1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZMK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMK1" } ] } ] }, { "uniprot_ac": "A0A8V0ZND5", "gene_name": "CSK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZND5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZND5" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0ZND5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZND5" } ] } ] }, { "uniprot_ac": "A0A8V0ZNP7", "gene_name": "SGK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZNP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNP7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZNP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNP7" } ] } ] }, { "uniprot_ac": "A0A8V0ZP30", "gene_name": "LTK", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZP30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP30" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0ZP30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP30" } ] } ] }, { "uniprot_ac": "A0A8V0ZPX2", "gene_name": "ALPK3", 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H(+).", "evidence": [ { "id": "A0A8V0ZRX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRX1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZRX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRX1" } ] }, { "ec_number": "2.1.1.-", "activity": "", "evidence": [ { "id": "A0A8V0ZRX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRX1" } ] } ] }, { "uniprot_ac": "A0A8V0ZSB4", "gene_name": "SIK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZSB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSB4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZSB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSB4" } ] } ] }, { "uniprot_ac": "A0A8V0ZSN8", "gene_name": "JAK1", "activity": [ { 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"2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZUU8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUU8" } ] } ] }, { "uniprot_ac": "A0A8V0ZUU9", "gene_name": "MKNK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZUU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUU9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZUU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUU9" } ] } ] }, { "uniprot_ac": "A0A8V0ZWC7", "gene_name": "EIF2AK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZWC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWC7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZWC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWC7" } ] } ] }, { "uniprot_ac": "A0A8V0ZWL6", "gene_name": "PIP4K2C", "activity": [ { "ec_number": "2.7.1.149", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-5-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZWL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWL6" } ] }, { "ec_number": "2.7.1.149", "activity": "", "evidence": [ { "id": "A0A8V0ZWL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWL6" } ] } ] }, { "uniprot_ac": "A0A8V0ZWV8", "gene_name": "TIE1", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZWV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWV8" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0ZWV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWV8" } ] } ] }, { "uniprot_ac": "A0A8V0ZWW1", "gene_name": "MAP3K12", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZWW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWW1" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0ZWW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWW1" } ] } ] }, { "uniprot_ac": "A0A8V0ZXD3", "gene_name": "EPHA4", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZXD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXD3" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0ZXD3", "database": 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O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A0Y8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0Y8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A0Y8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0Y8" } ] } ] }, { "uniprot_ac": "A0A8V1A1P3", "gene_name": "SRPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A1P3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1P3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A1P3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1P3" } ] } ] }, { "uniprot_ac": "A0A8V1A1Y7", "gene_name": "CDK2", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A1Y7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1Y7" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V1A1Y7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1Y7" } ] } ] }, { "uniprot_ac": "A0A8V1A2E6", "gene_name": "EPHB1", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A2E6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2E6" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V1A2E6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2E6" } ] } ] }, { "uniprot_ac": "A0A8V1A2T9", "gene_name": "MAP3K14", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A2T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2T9" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V1A2T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2T9" } ] } ] }, { "uniprot_ac": "A0A8V1A3N1", "gene_name": "MST1R", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A3N1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3N1" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V1A3N1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3N1" } ] } ] }, { "uniprot_ac": "A0A8V1A3T8", "gene_name": "MAST3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A3T8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3T8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A3T8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3T8" } ] } ] }, { "uniprot_ac": "A0A8V1A4A1", "gene_name": "CAMKK2", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4A1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4A1" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V1A4A1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4A1" } ] } ] }, { "uniprot_ac": "A0A8V1A4J8", "gene_name": "MAPKAPK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4J8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4J8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A4J8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4J8" } ] } ] }, { "uniprot_ac": "A0A8V1A4Q4", "gene_name": "MAPK3", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4Q4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4Q4" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V1A4Q4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4Q4" } ] } ] }, { "uniprot_ac": "A0A8V1A4V7", "gene_name": "HIPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4V7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4V7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A4V7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4V7" } ] } ] }, { "uniprot_ac": "A0A8V1A513", "gene_name": "DAPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A513", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A513" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A513", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A513" } ] } ] }, { "uniprot_ac": "A0A8V1A675", "gene_name": "CSNK1G2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A675", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A675" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A675", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A675" } ] } ] }, { "uniprot_ac": "A0A8V1A7E0", "gene_name": "DYRK3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7E0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E0" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V1A7E0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E0" } ] } ] }, { "uniprot_ac": "A0A8V1A7E9", "gene_name": "SIK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7E9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A7E9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E9" } ] } ] }, { "uniprot_ac": "A0A8V1A7M0", "gene_name": "STK39", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7M0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7M0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A7M0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7M0" } ] } ] }, { "uniprot_ac": "A0A8V1A7N1", "gene_name": "ERBB3", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7N1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7N1" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V1A7N1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7N1" } ] } ] }, { "uniprot_ac": "A0A8V1A7P9", "gene_name": "DCAF1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A7P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P9" } ] } ] }, { "uniprot_ac": "A0A8V1A9R2", "gene_name": "JAK3", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A9R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9R2" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V1A9R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9R2" } ] } ] }, { "uniprot_ac": "A0A8V1A9S5", "gene_name": "NUAK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A9S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9S5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A9S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9S5" } ] } ] }, { "uniprot_ac": "A0A8V1ABF3", "gene_name": "PRKAA2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] } ] }, { "uniprot_ac": "A0A8V1ABP4", "gene_name": "DSTYK", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABP4" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V1ABP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABP4" } ] } ] }, { "uniprot_ac": "A0A8V1ABR8", "gene_name": "CAMK4L", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABR8" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V1ABR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABR8" } ] } ] }, { "uniprot_ac": "A0A8V1AC40", "gene_name": "CDK18", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AC40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC40" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V1AC40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC40" } ] } ] }, { "uniprot_ac": "A0A8V1ACB5", "gene_name": "MAPK13", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACB5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V1ACB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACB5" } ] } ] }, { "uniprot_ac": "A0A8V1ACF6", "gene_name": "PIM1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACF6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ACF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACF6" } ] } ] }, { "uniprot_ac": "A0A8V1ACF7", "gene_name": "ABL1", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACF7" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V1ACF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACF7" } ] } ] }, { "uniprot_ac": "A0A8V1ACK0", "gene_name": "MAPKAPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACK0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ACK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACK0" } ] } ] }, { "uniprot_ac": "A0A8V1ACW2", "gene_name": "WNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACW2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ACW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACW2" } ] } ] }, { "uniprot_ac": "A0A8V1ADF0", "gene_name": "MAP2K2", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ADF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADF0" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V1ADF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADF0" } ] } ] }, { "uniprot_ac": "A0A8V1ADN9", "gene_name": "NLK", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ADN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADN9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V1ADN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADN9" } ] } ] }, { "uniprot_ac": "A0A8V1ADT4", "gene_name": "MKNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ADT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADT4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ADT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADT4" } ] } ] }, { "uniprot_ac": "A0A8V1AE45", "gene_name": "ERN1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AE45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE45" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AE45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE45" } ] } ] }, { "uniprot_ac": "A0A8V1AEH4", "gene_name": "STK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AEH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEH4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AEH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEH4" } ] } ] }, { "uniprot_ac": "A0A8V1AEL3", "gene_name": "ZAP70", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AEL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEL3" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V1AEL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEL3" } ] } ] }, { "uniprot_ac": "A0A8V1AFM7", "gene_name": "INSR", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AFM7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFM7" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V1AFM7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFM7" } ] } ] }, { "uniprot_ac": "A0A8V1AFS4", "gene_name": "STKLD1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AFS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFS4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AFS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFS4" } ] } ] }, { "uniprot_ac": "A0A8V1AG70", "gene_name": "LOC100857512", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AG70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AG70" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AG70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AG70" } ] } ] }, { "uniprot_ac": "A0A8V1AH12", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AH12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH12" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AH12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH12" } ] } ] }, { "uniprot_ac": "A0A8V1AHA8", "gene_name": "NEK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AHA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHA8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AHA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHA8" } ] } ] }, { "uniprot_ac": "A0A8V1AIY7", "gene_name": "AATK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AIY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIY7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AIY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIY7" } ] } ] }, { "uniprot_ac": "A0A8V1AJA4", "gene_name": "RPS6KB1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AJA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJA4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AJA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJA4" } ] } ] }, { "uniprot_ac": "A0A8V1AKW4", "gene_name": "MAP2K4", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AKW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKW4" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V1AKW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKW4" } ] } ] }, { "uniprot_ac": "A0A8V1AM12", "gene_name": "GSG2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AM12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM12" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AM12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM12" } ] } ] }, { "uniprot_ac": "A0A8V1AMK5", "gene_name": "PRKCA", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AMK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMK5" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V1AMK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMK5" } ] } ] }, { "uniprot_ac": "A0A8V1AMK9", "gene_name": "BAZ1B", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AMK9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMK9" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V1AMK9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMK9" } ] } ] }, { "uniprot_ac": "A0A8V1AMQ2", "gene_name": "CAMKK1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AMQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMQ2" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V1AMQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMQ2" } ] } ] }, { "uniprot_ac": "A0A8V1AP60", "gene_name": "KSR1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AP60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP60" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AP60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP60" } ] } ] }, { "uniprot_ac": "E1BQN6", "gene_name": "PRKCZ", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BQN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQN6" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1BQN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQN6" } ] } ] }, { "uniprot_ac": "E1BQV7", "gene_name": "SLK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BQV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQV7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BQV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQV7" } ] } ] }, { "uniprot_ac": "E1BTE1", "gene_name": "WEE2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BTE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BTE1" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "E1BTE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BTE1" } ] } ] }, { "uniprot_ac": "E1BTT3", "gene_name": "BMX", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BTT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BTT3" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "E1BTT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BTT3" } ] } ] }, { "uniprot_ac": "E1BUG0", "gene_name": "CDK12", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] } ] }, { "uniprot_ac": "E1BW33", "gene_name": "SMG1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BW33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BW33" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BW33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BW33" } ] } ] }, { "uniprot_ac": "E1BWA3", "gene_name": "PRKCI", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BWA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWA3" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1BWA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWA3" } ] } ] }, { "uniprot_ac": "E1BWT0", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BWT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWT0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BWT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWT0" } ] } ] }, { "uniprot_ac": "E1BX69", "gene_name": "EIF2AK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BX69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BX69" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BX69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BX69" } ] } ] }, { "uniprot_ac": "E1BY69", "gene_name": "PIM3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BY69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BY69" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BY69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BY69" } ] } ] }, { "uniprot_ac": "E1BYH2", "gene_name": "TAOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BYH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BYH2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BYH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BYH2" } ] } ] }, { "uniprot_ac": "E1C093", "gene_name": "PIK3CG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.154", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.154", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] } ] }, { "uniprot_ac": "E1C2C8", "gene_name": "MATK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C2C8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C2C8" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "E1C2C8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C2C8" } ] } ] }, { "uniprot_ac": "E1C2I2", "gene_name": "MASTL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C2I2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C2I2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C2I2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C2I2" } ] } ] }, { "uniprot_ac": "E1C581", "gene_name": "TBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C581", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C581" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C581", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C581" } ] } ] }, { "uniprot_ac": "E1C626", "gene_name": "TRAF6", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1C626", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C626" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "E1C626", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C626" } ] } ] }, { "uniprot_ac": "E1C6T4", "gene_name": "PRKD3", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C6T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C6T4" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1C6T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C6T4" } ] } ] }, { "uniprot_ac": "E1C764", "gene_name": "BMP2K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C764", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C764" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C764", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C764" } ] } ] }, { "uniprot_ac": "E1C7Z1", "gene_name": "FER", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C7Z1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C7Z1" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "E1C7Z1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C7Z1" } ] } ] }, { "uniprot_ac": "E1C848", "gene_name": "MAP3K8", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C848", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C848" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1C848", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C848" } ] } ] }, { "uniprot_ac": "F1N996", "gene_name": "PTK6", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N996", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N996" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F1N996", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N996" } ] } ] }, { "uniprot_ac": "F1N9Y5", "gene_name": "SYK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N9Y5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N9Y5" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F1N9Y5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N9Y5" } ] } ] }, { "uniprot_ac": "F1NA68", "gene_name": "CDK3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NA68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NA68" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1NA68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NA68" } ] } ] }, { "uniprot_ac": "F1NB57", "gene_name": "PLK2", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NB57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NB57" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "F1NB57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NB57" } ] } ] }, { "uniprot_ac": "F1NBT0", "gene_name": "STK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NBT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NBT0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1NBT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NBT0" } ] } ] }, { "uniprot_ac": "F1NCL8", "gene_name": "FGFR4", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NCL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCL8" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1NCL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCL8" } ] } ] }, { "uniprot_ac": "F1NCX7", "gene_name": "PLK1", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NCX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCX7" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "F1NCX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCX7" } ] } ] }, { "uniprot_ac": "F1NCY7", "gene_name": "MAPKAPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NCY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCY7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1NCY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCY7" } ] } ] }, { "uniprot_ac": "F1NJH1", "gene_name": "PRKCH", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NJH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NJH1" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1NJH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NJH1" } ] } ] }, { "uniprot_ac": "F1NJX6", "gene_name": "EPHA3", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NJX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NJX6" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1NJX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NJX6" } ] } ] }, { "uniprot_ac": "F1NKW3", "gene_name": "MAP3K15", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NKW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NKW3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1NKW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NKW3" } ] } ] }, { "uniprot_ac": "F1NLR7", "gene_name": "CLK3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NLR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NLR7" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "F1NLR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NLR7" } ] } ] }, { "uniprot_ac": "F1NQL9", "gene_name": "ROS1", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NQL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NQL9" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1NQL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NQL9" } ] } ] }, { "uniprot_ac": "F1NUX4", "gene_name": "MTOR", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NUX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NUX4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1NUX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NUX4" } ] } ] }, { "uniprot_ac": "F1NVF2", "gene_name": "MAP2K6", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NVF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NVF2" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "F1NVF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NVF2" } ] } ] }, { "uniprot_ac": "F1NW21", "gene_name": "KDR", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NW21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NW21" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1NW21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NW21" } ] } ] }, { "uniprot_ac": "F1NZY8", "gene_name": "TEC", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NZY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NZY8" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F1NZY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NZY8" } ] } ] }, { "uniprot_ac": "F1P011", "gene_name": "CAMK2A", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1P011", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P011" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "F1P011", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P011" } ] } ] }, { "uniprot_ac": "F1P356", "gene_name": "NUAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1P356", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P356" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1P356", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P356" } ] } ] }, { "uniprot_ac": "F1P4G3", "gene_name": "HIPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1P4G3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P4G3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1P4G3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P4G3" } ] } ] }, { "uniprot_ac": "H9KZZ1", "gene_name": "NTRK1", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "H9KZZ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H9KZZ1" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "H9KZZ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H9KZZ1" } ] } ] }, { "uniprot_ac": "H9KZZ2", "gene_name": "INSRR", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "H9KZZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H9KZZ2" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "H9KZZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H9KZZ2" } ] } ] }, { "uniprot_ac": "O42422", "gene_name": "EPHA7", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "O42422", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O42422" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "O42422", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O42422" } ] } ] }, { "uniprot_ac": "P00523", "gene_name": "SRC", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "P00523", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00523" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "P00523", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00523" } ] } ] }, { "uniprot_ac": "P05625", "gene_name": "RAF1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P05625", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05625" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P05625", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05625" } ] } ] }, { "uniprot_ac": "P08941", "gene_name": "ROS1", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "P08941", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P08941" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "P08941", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P08941" } ] } ] }, { "uniprot_ac": "P09324", "gene_name": "YES1", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "P09324", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P09324" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "P09324", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P09324" } ] } ] }, { "uniprot_ac": "P10741", "gene_name": "MOS", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P10741", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P10741" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P10741", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P10741" } ] } ] }, { "uniprot_ac": "P13387", "gene_name": "EGFR", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "P13387", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13387" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "P13387", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13387" } ] } ] }, { "uniprot_ac": "P13863", "gene_name": "CDK1", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P13863", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13863" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "P13863", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13863" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "P13863", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13863" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "P13863", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13863" } ] } ] }, { "uniprot_ac": "P18460", "gene_name": "FGFR3", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "P18460", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P18460" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "P18460", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P18460" } ] } ] }, { "uniprot_ac": "P18461", "gene_name": "FGFR2", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "P18461", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P18461" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "P18461", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P18461" } ] } ] }, { "uniprot_ac": "P18652", "gene_name": "RPS6KA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P18652", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P18652" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P18652", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P18652" } ] } ] }, { "uniprot_ac": "P21804", "gene_name": "FGFR1", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "P21804", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P21804" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "P21804", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P21804" } ] } ] }, { "uniprot_ac": "P21868", "gene_name": "CSNK2A1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P21868", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P21868" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P21868", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P21868" } ] } ] }, { "uniprot_ac": "P21869", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P21869", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P21869" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P21869", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P21869" } ] } ] }, { "uniprot_ac": "P28693", "gene_name": "EPHB2", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "P28693", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P28693" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "P28693", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P28693" } ] } ] }, { "uniprot_ac": "P29318", "gene_name": "EPHA3", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "P29318", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P29318" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "P29318", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P29318" } ] } ] }, { "uniprot_ac": "P41239", "gene_name": "CSK", "activity": [ { "ec_number": "2.7.10.4", "activity": "ATP + [a protein]-(L-tyrosine) = ADP + [a protein]-(L-tyrosine)-phosphate. The optimal peptide substrate contains the sequence (relative to the phosphorylated tyrosine): Glu-Glu-Asp/Glu-Ile-Tyr-Phe-Phe-Phe-Phe. Physiological substrates are C-terminal tail of Src-family protein kinases.", "evidence": [ { "id": "P41239", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P41239" } ] }, { "ec_number": "2.7.10.4", "activity": "", "evidence": [ { "id": "P41239", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P41239" } ] } ] }, { "uniprot_ac": "P42683", "gene_name": "LCK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "P42683", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P42683" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "P42683", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P42683" } ] } ] }, { "uniprot_ac": "P53666", "gene_name": "LIMK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P53666", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P53666" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P53666", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P53666" } ] } ] }, { "uniprot_ac": "P54755", "gene_name": "EPHA5", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "P54755", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P54755" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "P54755", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P54755" } ] } ] }, { "uniprot_ac": "P67962", "gene_name": "CSNK1A1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P67962", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P67962" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P67962", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P67962" } ] } ] }, { "uniprot_ac": "P79996", "gene_name": "MAPK9", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P79996", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P79996" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "P79996", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P79996" } ] } ] }, { "uniprot_ac": "Q00944", "gene_name": "PTK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q00944", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q00944" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "Q00944", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q00944" } ] } ] }, { "uniprot_ac": "Q02977", "gene_name": "YRK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q02977", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q02977" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "Q02977", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q02977" } ] } ] }, { "uniprot_ac": "Q04982", "gene_name": "BRAF", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q04982", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q04982" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q04982", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q04982" } ] } ] }, { "uniprot_ac": "Q05876", "gene_name": "FYN", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q05876", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q05876" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "Q05876", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q05876" } ] } ] }, { "uniprot_ac": "Q07494", "gene_name": "EPHB1", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q07494", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q07494" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "Q07494", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q07494" } ] } ] }, { "uniprot_ac": "Q07496", "gene_name": "EPHA4", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q07496", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q07496" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "Q07496", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q07496" } ] } ] }, { "uniprot_ac": "Q07497", "gene_name": "EPHB5", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q07497", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q07497" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "Q07497", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q07497" } ] } ] }, { "uniprot_ac": "Q07498", "gene_name": "EPHB3", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q07498", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q07498" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "Q07498", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q07498" } ] } ] }, { "uniprot_ac": "Q08156", "gene_name": "KIT", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q08156", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08156" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "Q08156", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08156" } ] } ] }, { "uniprot_ac": "Q0GGW5", "gene_name": "STK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q0GGW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0GGW5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q0GGW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0GGW5" } ] } ] }, { "uniprot_ac": "Q5F3L1", "gene_name": "RPS6KA5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5F3L1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F3L1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q5F3L1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F3L1" } ] } ] }, { "uniprot_ac": "Q5F3W3", "gene_name": "MAPK6", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5F3W3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F3W3" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "Q5F3W3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F3W3" } ] } ] }, { "uniprot_ac": "Q5ZIU3", "gene_name": "DYRK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5ZIU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZIU3" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "Q5ZIU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZIU3" } ] } ] }, { "uniprot_ac": "Q5ZJH6", "gene_name": "ULK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5ZJH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJH6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q5ZJH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJH6" } ] } ] }, { "uniprot_ac": "Q5ZJK4", "gene_name": "STK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5ZJK4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJK4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q5ZJK4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJK4" } ] } ] }, { "uniprot_ac": "Q5ZJS0", "gene_name": "CSNK1G1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5ZJS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJS0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q5ZJS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJS0" } ] } ] }, { "uniprot_ac": "Q5ZKI0", "gene_name": "CAMK2D", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5ZKI0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKI0" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "Q5ZKI0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKI0" } ] } ] }, { "uniprot_ac": "Q5ZKN1", "gene_name": "CDK9", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5ZKN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKN1" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "Q5ZKN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKN1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q5ZKN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKN1" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "Q5ZKN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKN1" } ] } ] }, { "uniprot_ac": "Q5ZLL1", "gene_name": "CSNK1E", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5ZLL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZLL1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q5ZLL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZLL1" } ] } ] }, { "uniprot_ac": "Q6U1I9", "gene_name": "SGK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q6U1I9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6U1I9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": 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"n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1NXP2-1", "uniprot_ac": "F1NXP2", "uniprot_id": "F1NXP2_CHICK", "mass": { "chemical_mass": 34806.0, "monoisotopic_mass": 34806.0 }, "refseq": { "ac": "XP_422356", "name": "transcription initiation factor IIB isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_422356" }, "gene_names": [ { "name": "GTF2B", "type": "recommended", "evidence": [ { "id": "F1NXP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NXP2" } ] }, { "name": "GTF2B", "type": "synonym", "evidence": [ { "id": "XP_422356", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_422356" } ] } ], "protein_names": [ { "name": "Transcription initiation factor IIB", "type": "recommended", "evidence": [ { "id": "F1NXP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NXP2/entry#names_and_taxonomy" } ] }, { "name": "2.3.1.48", "type": "synonym", "evidence": [ { "id": "F1NXP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NXP2/entry#names_and_taxonomy" } ] }, { "name": "General transcription factor TFIIB", "type": "synonym", "evidence": [ { "id": "F1NXP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NXP2/entry#names_and_taxonomy" } ] }, { "name": "transcription initiation factor IIB isoform X2", "type": "synonym", "evidence": [ { "id": "XP_422356", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_422356" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052539.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Dec 16, 2011 this sequence version replaced XP_422356.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_422356", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_422356" } ] }, { "annotation": "General transcription factor that plays a role in transcription initiation by RNA polymerase II (Pol II). Involved in the pre-initiation complex (PIC) formation and Pol II recruitment at promoter DNA. Together with the TATA box-bound TBP forms the core initiation complex and provides a bridge between TBP and the Pol II-TFIIF complex. Released from the PIC early following the onset of transcription during the initiation and elongation transition and reassociates with TBP during the next transcription cycle. Associates with chromatin to core promoter-specific regions. Binds to two distinct DNA core promoter consensus sequence elements in a TBP-independent manner; these IIB-recognition elements (BREs) are localized immediately upstream (BREu), 5'-[GC][GC][GA]CGCC-3', and downstream (BREd), 5'-[GA]T[TGA][TG][GT][TG][TG]-3', of the TATA box element. Modulates transcription start site selection. Also exhibits autoacetyltransferase activity that contributes to the activated transcription.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZTE0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTE0#function" }, { "database": "UniProtKB", "id": "ARBA00056112", "url": "https://www.uniprot.org/uniprotkb/ARBA00056112#function" }, { "database": "UniProtKB", "id": "A0A1D5P699", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P699#function" }, { "database": "UniProtKB", "id": "F1NXP2", "url": "https://www.uniprot.org/uniprotkb/F1NXP2#function" }, { "database": "UniProtKB", "id": "A0A8V0ZK95", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK95#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NXP2", "url": "https://www.uniprot.org/uniprotkb/F1NXP2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "GTF2B", "url": "https://www.uniprot.org/uniprotkb/F1NXP2", "locus": { "chromosome": "8", "start_pos": 14901274, "end_pos": 14883133, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010022930", "url": "https://www.ensembl.org/id/ENSGALG00010022930" } ] } } ], "crossref": [ { "id": "F1NXP2", "url": "https://alphafold.ebi.ac.uk/entry/F1NXP2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000006205", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000006205", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd20551", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd20551", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd20552", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd20552", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "424518", "url": "https://www.ncbi.nlm.nih.gov/gene/424518", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000812", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000812", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013137", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013137", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013150", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013150", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013763", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013763", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023486", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023486", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036915", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036915", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:424518", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424518", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A1D5P699", "url": "https://www.orthodb.org/?gene=A0A1D5P699", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZK95", "url": "https://www.orthodb.org/?gene=A0A8V0ZK95", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZTE0", "url": "https://www.orthodb.org/?gene=A0A8V0ZTE0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NXP2", "url": "https://www.orthodb.org/?gene=F1NXP2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11618", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11618", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11618:SF77", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11618:SF77", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00382", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00382", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08271", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08271", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-674695", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-674695", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-6807505", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6807505", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-73776", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-73776", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-73779", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-73779", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-75953", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-75953", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-76042", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-76042", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_422356", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_422356", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "45948", "url": "https://www.rhea-db.org/rhea/45948", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A1D5P699", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P699", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5P699-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P699-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZK95", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK95", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZK95-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK95-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZTE0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTE0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZTE0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTE0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NXP2", "url": "https://www.uniprot.org/uniprotkb/F1NXP2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NXP2-1", "url": "https://www.uniprot.org/uniprotkb/F1NXP2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASTSRLDALPRVTCPNHPDSILVEDYRAGDMICSECGLVVGDRVIDVGSEWRTFSNDKATKDPSRVGDTQNPLLSDGDLSTMIGKGTGAASFDEFGNSKYQNRRTMSSSDRAMMNAFKEITNMADRINLPRNIVDRTNNLFKQVYEQKSLKGRSNDAIASACLYIACRQEGVPRTFKEICAVSRISKKEIGRCFKLILKALETSVDLITTGDFMSRFCSNLGLPKQVQMAATHIARKAVELDLVPGRSPISVAAAAIYMASQASAEKRTQKEIGDIAGVADVTIRQSYRLIYPRAPDLFPADFKFDTPVDKLPQL", "length": 316, "header": "tr|F1NXP2-1|F1NXP2_CHICK Isoform 1 of Transcription initiation factor IIB OS=Gallus gallus OX=9031 GN=GTF2B PE=1 SV=2 CANONICAL=F1NXP2-1" }, "isoforms": [ { "isoform_ac": "A0A1D5P699-1", "url": "https://www.uniprot.org/uniprotkb/F1NXP2/entry#A0A1D5P699-1", "sequence": { "sequence": "MSLDALPRVTCPNHPDSILVEDYRAGDMICSECGLVVGDRVIDVGSEWRTFSNDKATKDPSRVGDTQNPLLSDGDLSTMIGKGTGAASFDEFGNSKYQNRRTMSSSDRAMMNAFKEITNMADRINLPRNIVDRTNNLFKQVYEQKSLKGRSNDAIASACLYIACRQEGVPRTFKEICAVSRISKKEIGRCFKLILKALETSVDLITTGDFMSRFCSNLGLPKQVQMAATHIARKAVELDLVPGRSPISVAAAAIYMASQASAEKRTQKEIGDIAGVADVTIRQSYRLIYPRAPDLFPADFKFDTPVDKLPQL", "length": 312, "header": "tr|A0A1D5P699-1|A0A1D5P699_CHICK Computationally mapped isoform of Transcription initiation factor IIB OS=Gallus gallus OX=9031 GN=GTF2B PE=1 SV=1 CANONICAL=F1NXP2-1" }, "locus": { "chromosome": "8", "start_pos": 14900454, "end_pos": 14884394, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010055795.1", "url": "https://www.ensembl.org/id/ENSGALT00010055795.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033776.1", "url": "https://www.ensembl.org/id/ENSGALP00010033776.1" } ] } }, { "isoform_ac": "A0A8V0ZK95-1", "url": "https://www.uniprot.org/uniprotkb/F1NXP2/entry#A0A8V0ZK95-1", "sequence": { "sequence": "MASTSRLDALPRVTCPNHPDSILVEDYRAGDMICSECGLVVGDRVIDVGSEWRTFSNDKATKDPSRVGDTQNPLLSDGDLSTMIGKGTGAASFDEFGNSKYQNRRTMSSSDRAMMNAFKEITNMADRINLPRNIVDRTNNLFKQVYEQKSLKGRSNDAIASACLYIACRQEGVPRTFKEICAVSRISKKEIGRCFKLILKALETSVDLITTGDFMSRFCSNLGLPKQVQMAATHIARKAVELDLVPGRSPISVAAAAIYMASQASAEKRTQKGKTFFNILLLKRELTFSVDLEAAVPMARSRDQTRICCFTQ", "length": 312, "header": "tr|A0A8V0ZK95-1|A0A8V0ZK95_CHICK Computationally mapped isoform of Transcription initiation factor IIB OS=Gallus gallus OX=9031 GN=GTF2B PE=1 SV=1 CANONICAL=F1NXP2-1" }, "locus": { "chromosome": "8", "start_pos": 14900270, "end_pos": 14883230, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010055809.1", "url": "https://www.ensembl.org/id/ENSGALT00010055809.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033788.1", "url": "https://www.ensembl.org/id/ENSGALP00010033788.1" } ] } }, { "isoform_ac": "A0A8V0ZTE0-1", "url": "https://www.uniprot.org/uniprotkb/F1NXP2/entry#A0A8V0ZTE0-1", "sequence": { "sequence": "MASTSRLDALPRVTCPNHPDSILVEDYRAGDMICSECGLVYPVSEEGALSTSDHVEGFCGSCEIFKPPNGEKPFHICDRVIDVGSEWRTFSNDKATKDPSRVGDTQNPLLSDGDLSTMIGKGTGAASFDEFGNSKYQNRRTMSSSDRAMMNAFKEITNMADRINLPRNIVDRTNNLFKQVYEQKSLKGRSNDAIASACLYIACRQEGVPRTFKEICAVSRISKKEIGRCFKLILKALETSVDLITTGDFMSRFCSNLGLPKQVQMAATHIARKAVELDLVPGRSPISVAAAAIYMASQASAEKRTQKEIGDIAGVADVTIRQSYRLIYPRAPDLFPADFKFDTPVDKLPQL", "length": 351, "header": "tr|A0A8V0ZTE0-1|A0A8V0ZTE0_CHICK Computationally mapped isoform of Transcription initiation factor IIB OS=Gallus gallus OX=9031 GN=GTF2B PE=1 SV=1 CANONICAL=F1NXP2-1" }, "locus": { "chromosome": "8", "start_pos": 14900454, "end_pos": 14883230, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010055801.1", "url": "https://www.ensembl.org/id/ENSGALT00010055801.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033781.1", "url": "https://www.ensembl.org/id/ENSGALP00010033781.1" } ] } }, { "isoform_ac": "F1NXP2-1", "url": "https://www.uniprot.org/uniprotkb/F1NXP2/entry#F1NXP2-1", "sequence": { "sequence": "MASTSRLDALPRVTCPNHPDSILVEDYRAGDMICSECGLVVGDRVIDVGSEWRTFSNDKATKDPSRVGDTQNPLLSDGDLSTMIGKGTGAASFDEFGNSKYQNRRTMSSSDRAMMNAFKEITNMADRINLPRNIVDRTNNLFKQVYEQKSLKGRSNDAIASACLYIACRQEGVPRTFKEICAVSRISKKEIGRCFKLILKALETSVDLITTGDFMSRFCSNLGLPKQVQMAATHIARKAVELDLVPGRSPISVAAAAIYMASQASAEKRTQKEIGDIAGVADVTIRQSYRLIYPRAPDLFPADFKFDTPVDKLPQL", "length": 316, "header": "tr|F1NXP2-1|F1NXP2_CHICK Isoform 1 of Transcription initiation factor IIB OS=Gallus gallus OX=9031 GN=GTF2B PE=1 SV=2 CANONICAL=F1NXP2-1" }, "locus": { "chromosome": "8", "start_pos": 14900454, "end_pos": 14883230, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010055808.1", "url": "https://www.ensembl.org/id/ENSGALT00010055808.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033787.1", "url": "https://www.ensembl.org/id/ENSGALP00010033787.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "gga:424518", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424518", "resource": "KEGG Pathway" }, { "id": "R-GGA-674695", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-674695", "resource": "Reactome", "description": "RNA Polymerase II Pre-transcription Events" }, { "id": "R-GGA-6807505", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6807505", "resource": "Reactome", "description": "RNA polymerase II transcribes snRNA genes" }, { "id": "R-GGA-73776", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-73776", "resource": "Reactome", "description": "RNA Polymerase II Promoter Escape" }, { "id": "R-GGA-73779", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-73779", "resource": "Reactome", "description": "RNA Polymerase II Transcription Pre-Initiation And Promoter Opening" }, { "id": "R-GGA-75953", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-75953", "resource": "Reactome", "description": "RNA Polymerase II Transcription Initiation" }, { "id": "R-GGA-76042", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-76042", "resource": "Reactome", "description": "RNA Polymerase II Transcription Initiation And Promoter Clearance" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 10, "go_terms": [ { "name": "protein-lysine-acetyltransferase activity", "id": "GO:0061733", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061733", "evidence": [ { "database": "UniProtKB", "id": "F1NXP2", "url": "https://www.uniprot.org/uniprotkb/F1NXP2" } ], "pmid": "" }, { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "F1NXP2", "url": "https://www.uniprot.org/uniprotkb/F1NXP2" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "F1NXP2", "url": "https://www.uniprot.org/uniprotkb/F1NXP2" } ], "pmid": "" }, { "name": "TBP-class protein binding", "id": "GO:0017025", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017025", "evidence": [ { "database": "UniProtKB", "id": "F1NXP2", "url": "https://www.uniprot.org/uniprotkb/F1NXP2" } ], "pmid": "" }, { "name": "promoter-specific chromatin binding", "id": "GO:1990841", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990841", "evidence": [ { "database": "UniProtKB", "id": "F1NXP2", "url": "https://www.uniprot.org/uniprotkb/F1NXP2" } ], "pmid": "" }, { "name": "RNA polymerase II core promoter sequence-specific DNA binding", "id": "GO:0000979", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000979", "evidence": [ { "database": "UniProtKB", "id": "F1NXP2", "url": "https://www.uniprot.org/uniprotkb/F1NXP2" } ], "pmid": "" }, { "name": "RNA polymerase II complex binding", "id": "GO:0000993", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000993", "evidence": [ { "database": "UniProtKB", "id": "F1NXP2", "url": "https://www.uniprot.org/uniprotkb/F1NXP2" } ], "pmid": "" }, { "name": "nuclear thyroid hormone receptor binding", "id": "GO:0046966", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046966", "evidence": [ { "database": "UniProtKB", "id": "F1NXP2", "url": "https://www.uniprot.org/uniprotkb/F1NXP2" } ], "pmid": "" }, { "name": "acetyltransferase activity", "id": "GO:0016407", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016407", "evidence": [ { "database": "UniProtKB", "id": "F1NXP2", "url": "https://www.uniprot.org/uniprotkb/F1NXP2" } ], "pmid": "" }, { "name": "RNA polymerase II general transcription initiation factor activity", "id": "GO:0016251", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016251", "evidence": [ { "database": "UniProtKB", "id": "F1NXP2", "url": "https://www.uniprot.org/uniprotkb/F1NXP2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 8, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1NXP2", "url": "https://www.uniprot.org/uniprotkb/F1NXP2" } ], "pmid": "" }, { "name": "chromosome", "id": "GO:0005694", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005694", "evidence": [ { "database": "UniProtKB", "id": "F1NXP2", "url": "https://www.uniprot.org/uniprotkb/F1NXP2" } ], "pmid": "" }, { "name": "transcription preinitiation complex", "id": "GO:0097550", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097550", "evidence": [ { "database": "UniProtKB", "id": "F1NXP2", "url": "https://www.uniprot.org/uniprotkb/F1NXP2" } ], "pmid": "" }, { "name": "nuclear body", "id": "GO:0016604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016604", "evidence": [ { "database": "UniProtKB", "id": "F1NXP2", "url": "https://www.uniprot.org/uniprotkb/F1NXP2" } ], "pmid": "" }, { "name": "kinetochore", "id": "GO:0000776", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000776", "evidence": [ { "database": "UniProtKB", "id": "F1NXP2", "url": "https://www.uniprot.org/uniprotkb/F1NXP2" } ], "pmid": "" }, { "name": "transcription factor TFIID complex", "id": "GO:0005669", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005669", "evidence": [ { "database": "UniProtKB", "id": "F1NXP2", "url": "https://www.uniprot.org/uniprotkb/F1NXP2" } ], "pmid": "" }, { "name": "germinal vesicle", "id": "GO:0042585", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042585", "evidence": [ { "database": "UniProtKB", "id": "F1NXP2", "url": "https://www.uniprot.org/uniprotkb/F1NXP2" } ], "pmid": "" }, { "name": "cell division site", "id": "GO:0032153", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032153", "evidence": [ { "database": "UniProtKB", "id": "F1NXP2", "url": "https://www.uniprot.org/uniprotkb/F1NXP2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 8, "go_terms": [ { "name": "transcription preinitiation complex assembly", "id": "GO:0070897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070897", "evidence": [ { "database": "UniProtKB", "id": "F1NXP2", "url": "https://www.uniprot.org/uniprotkb/F1NXP2" } ], "pmid": "" }, { "name": "viral transcription", "id": "GO:0019083", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019083", "evidence": [ { "database": "UniProtKB", "id": "F1NXP2", "url": "https://www.uniprot.org/uniprotkb/F1NXP2" } ], "pmid": "" }, { "name": "spindle assembly", "id": "GO:0051225", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051225", "evidence": [ { "database": "UniProtKB", "id": "F1NXP2", "url": "https://www.uniprot.org/uniprotkb/F1NXP2" } ], "pmid": "" }, { "name": "DNA-templated transcription initiation", "id": "GO:0006352", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006352", "evidence": [ { "database": "UniProtKB", "id": "F1NXP2", "url": "https://www.uniprot.org/uniprotkb/F1NXP2" } ], "pmid": "" }, { "name": "RNA polymerase II preinitiation complex assembly", "id": "GO:0051123", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051123", "evidence": [ { "database": "UniProtKB", "id": "F1NXP2", "url": "https://www.uniprot.org/uniprotkb/F1NXP2" } ], "pmid": "" }, { "name": "meiotic sister chromatid cohesion", "id": "GO:0051177", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051177", "evidence": [ { "database": "UniProtKB", "id": "F1NXP2", "url": "https://www.uniprot.org/uniprotkb/F1NXP2" } ], "pmid": "" }, { "name": "transcriptional start site selection at RNA polymerase II promoter", "id": "GO:0001174", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001174", "evidence": [ { "database": "UniProtKB", "id": "F1NXP2", "url": "https://www.uniprot.org/uniprotkb/F1NXP2" } ], "pmid": "" }, { "name": "RNA polymerase II core complex assembly", "id": "GO:1990114", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990114", "evidence": [ { "database": "UniProtKB", "id": "F1NXP2", "url": "https://www.uniprot.org/uniprotkb/F1NXP2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "45948", "name": "", "equation": "L-lysyl-[protein] + acetyl-CoA = N(6)-acetyl-L-lysyl-[protein] + CoA + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YX99-1", "F1NXP2-1", "A0A8V0X6X9-1", "A0A8V0ZTT2-1", "A0A8V0ZMX8-1", "A0A8V0ZRQ2-1", "A0A8V0X885-1", "A0A8V0Z594-1", "A0A8V0ZR91-1" ], "evidence": [ { "id": "45948", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/45948" } ] }, { "id": "R-GGA-109637", "name": "Binding of TFIIA and TFIIB to the pol II promoter:TFIID complex", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1NXP2-1" ], "evidence": [ { "id": "R-GGA-109637", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-109637" } ] }, { "id": "R-GGA-109639", "name": "Formation of the closed pre-initiation complex", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1NCB0-1", "F1NZ23-1", "F1NXP2-1", "A0A8V0Y2I5-1" ], "evidence": [ { "id": "R-GGA-109639", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-109639" } ] }, { "id": "R-GGA-6810233", "name": "CDK7 phosphorylates serine-5 and serine-7 of heptad repeats in C-terminal domain of RNA polymerase II at snRNA promoter", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1NCB0-1", "F1NXP2-1", "A0A8V0Y2I5-1" ], "evidence": [ { "id": "R-GGA-6810233", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6810233" } ] }, { "id": "R-GGA-6810235", "name": "RPAP2 binds RNA polymerase II phosphorylated at serine-7 residues of heptad repeats in the C-terminal domain", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1NCB0-1", "A0A8V0ZMX1-1", "F1NXP2-1", "A0A8V0Y2I5-1" ], "evidence": [ { "id": "R-GGA-6810235", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6810235" } ] }, { "id": "R-GGA-6814549", "name": "Pre-snRNA transcript initiation, Integrator binding, LEC binding", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1NCB0-1", "A0A8V0ZMX1-1", "F1NXP2-1", "A0A8V0Y2I5-1" ], "evidence": [ { "id": "R-GGA-6814549", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6814549" } ] }, { "id": "R-GGA-6814555", "name": "Integrator complex processes the 3' end of snRNA", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1NCB0-1", "Q5ZJQ7-1", "A0A8V0ZMX1-1", "F1NXP2-1", "A0A8V0Y2I5-1" ], "evidence": [ { "id": "R-GGA-6814555", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6814555" } ] }, { "id": "R-GGA-6814559", "name": "Pre-snRNA is elongated and capped with 7-methylguanosine", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1NCB0-1", "A0A8V0ZMX1-1", "F1NXP2-1", "A0A8V0Y2I5-1" ], "evidence": [ { "id": "R-GGA-6814559", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6814559" } ] }, { "id": "R-GGA-75095", "name": "Binding of TFIIE to the growing preinitiation complex", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1NCB0-1", "F1NXP2-1" ], "evidence": [ { "id": "R-GGA-75095", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-75095" } ] }, { "id": "R-GGA-75861", "name": "NTP Binds Active Site of RNA Polymerase II", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1NCB0-1", "F1NZ23-1", "F1NXP2-1", "A0A8V0Y2I5-1" ], "evidence": [ { "id": "R-GGA-75861", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-75861" } ] }, { "id": "R-GGA-75862", "name": "Fall Back to Closed Pre-initiation Complex", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1NCB0-1", "F1NZ23-1", "F1NXP2-1", "A0A8V0Y2I5-1" ], "evidence": [ { "id": "R-GGA-75862", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-75862" } ] }, { "id": "R-GGA-75864", "name": "Newly Formed Phosphodiester Bond Stabilized and PPi Released", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1NCB0-1", "F1NZ23-1", "F1NXP2-1", "A0A8V0Y2I5-1" ], "evidence": [ { "id": "R-GGA-75864", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-75864" } ] }, { "id": "R-GGA-75866", "name": "Nucleophillic Attack by 3'-hydroxyl Oxygen of nascent transcript on the Alpha Phosphate of NTP", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1NCB0-1", "F1NZ23-1", "F1NXP2-1", "A0A8V0Y2I5-1" ], "evidence": [ { "id": "R-GGA-75866", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-75866" } ] }, { "id": "R-GGA-75949", "name": "RNA Polymerase II Promoter Opening: First Transition", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1NCB0-1", "F1NZ23-1", "F1NXP2-1", "A0A8V0Y2I5-1" ], "evidence": [ { "id": "R-GGA-75949", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-75949" } ] }, { "id": "R-GGA-9613494", "name": "Unwinding of DNA for the Nascent Transcript: Second Transition", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1NCB0-1", "F1NZ23-1", "F1NXP2-1", "A0A8V0Y2I5-1" ], "evidence": [ { "id": "R-GGA-9613494", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9613494" } ] }, { "id": "R-GGA-9613497", "name": "Unwinding DNA for the nascent transcript", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [ "R-ALL-9757634" ], "output_participant_list": [ "R-ALL-113541" ], "enzyme_list": [ "F1NCB0-1", "F1NZ23-1", "F1NXP2-1", "A0A8V0Y2I5-1" ], "evidence": [ { "id": "R-GGA-9613497", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9613497" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-113541", "participant_name": "PPi [nucleoplasm]", "crossref": [ { "id": "4097574", "database": "PubChem Compound", "url": "" }, { "id": "1023", "database": "PubChem Compound", "url": "" }, { "id": "33019", "database": "ChEBI", "url": "" }, { "id": "PPI", "database": "AraCyc", "url": "" }, { "id": "ZINC000006827695", "database": "ZINC", "url": "" }, { "id": "2466", "database": "CAS", "url": "" }, { "id": "2466-09-3", "database": "CAS", "url": "" }, { "id": "C00013", "database": "COMPOUND", "url": "" } ] }, { "participant_id": "R-ALL-9757634", "participant_name": "NTP [nucleoplasm]", "crossref": [ { "id": "61557", "database": "ChEBI", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A0A8V0X6X9", "gene_name": "KAT2B", "activity": [ { "ec_number": "2.3.1.48", "activity": "L-lysyl-[histone] + acetyl-CoA = N(6)-acetyl-L-lysyl-[histone] + CoA + H(+).", "evidence": [ { "id": "A0A8V0X6X9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X6X9" } ] }, { "ec_number": "2.3.1.48", "activity": "", "evidence": [ { "id": "A0A8V0X6X9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X6X9" } ] } ] }, { "uniprot_ac": "A0A8V0X885", "gene_name": "", "activity": [ { "ec_number": "2.3.1.48", "activity": "L-lysyl-[histone] + acetyl-CoA = N(6)-acetyl-L-lysyl-[histone] + CoA + H(+).", "evidence": [ { "id": "A0A8V0X885", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X885" } ] }, { "ec_number": "2.3.1.48", "activity": "", "evidence": [ { "id": "A0A8V0X885", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X885" } ] } ] }, { "uniprot_ac": "A0A8V0Y2I5", "gene_name": "CDK7", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] }, { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] } ] }, { "uniprot_ac": "A0A8V0YX99", "gene_name": "NAA60", "activity": [ { "ec_number": "2.3.1.48", "activity": "L-lysyl-[histone] + acetyl-CoA = N(6)-acetyl-L-lysyl-[histone] + CoA + H(+).", "evidence": [ { "id": "A0A8V0YX99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YX99" } ] }, { "ec_number": "2.3.1.259", "activity": "N-terminal L-methionyl-[transmembrane protein] + acetyl-CoA = N-terminal N(alpha)-acetyl-L-methionyl-[transmembrane protein] + CoA + H(+).", "evidence": [ { "id": "A0A8V0YX99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YX99" } ] }, { "ec_number": "2.3.1.259", "activity": "", "evidence": [ { "id": "A0A8V0YX99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YX99" } ] }, { "ec_number": "2.3.1.48", "activity": "", "evidence": [ { "id": "A0A8V0YX99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YX99" } ] } ] }, { "uniprot_ac": "A0A8V0Z594", "gene_name": "KAT6A", "activity": [ { "ec_number": "2.3.1.48", "activity": "L-lysyl-[histone] + acetyl-CoA = N(6)-acetyl-L-lysyl-[histone] + CoA + H(+).", "evidence": [ { "id": "A0A8V0Z594", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z594" } ] }, { "ec_number": "2.3.1.48", "activity": "", "evidence": [ { "id": "A0A8V0Z594", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z594" } ] } ] }, { "uniprot_ac": "A0A8V0ZMX1", "gene_name": "RPAP2", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZMX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMX1" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0ZMX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMX1" } ] } ] }, { "uniprot_ac": "A0A8V0ZMX8", "gene_name": "KAT6B", "activity": [ { "ec_number": "2.3.1.48", "activity": "L-lysyl-[histone] + acetyl-CoA = N(6)-acetyl-L-lysyl-[histone] + CoA + H(+).", "evidence": [ { "id": "A0A8V0ZMX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMX8" } ] }, { "ec_number": "2.3.1.48", "activity": "", "evidence": [ { "id": "A0A8V0ZMX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMX8" } ] } ] }, { "uniprot_ac": "A0A8V0ZR91", "gene_name": "KAT7", "activity": [ { "ec_number": "2.3.1.48", "activity": "L-lysyl-[histone] + acetyl-CoA = N(6)-acetyl-L-lysyl-[histone] + CoA + H(+).", "evidence": [ { "id": "A0A8V0ZR91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR91" } ] }, { "ec_number": "2.3.1.48", "activity": "", "evidence": [ { "id": "A0A8V0ZR91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR91" } ] } ] }, { "uniprot_ac": "A0A8V0ZRQ2", "gene_name": "HAT1", "activity": [ { "ec_number": "2.3.1.48", "activity": "L-lysyl-[histone] + acetyl-CoA = N(6)-acetyl-L-lysyl-[histone] + CoA + H(+).", "evidence": [ { "id": "A0A8V0ZRQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRQ2" } ] }, { "ec_number": "2.3.1.48", "activity": "", "evidence": [ { "id": "A0A8V0ZRQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRQ2" } ] } ] }, { "uniprot_ac": "A0A8V0ZTT2", "gene_name": "KAT2A", "activity": [ { "ec_number": "2.3.1.48", "activity": "L-lysyl-[histone] + acetyl-CoA = N(6)-acetyl-L-lysyl-[histone] + CoA + H(+).", "evidence": [ { "id": "A0A8V0ZTT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTT2" } ] }, { "ec_number": "2.3.1.48", "activity": "", "evidence": [ { "id": "A0A8V0ZTT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTT2" } ] } ] }, { "uniprot_ac": "F1NCB0", "gene_name": "POLR2B", "activity": [ { "ec_number": "2.7.7.6", "activity": "RNA(n) + a ribonucleoside 5'-triphosphate = RNA(n+1) + diphosphate.", "evidence": [ { "id": "F1NCB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCB0" } ] }, { "ec_number": "2.7.7.6", "activity": "", "evidence": [ { "id": "F1NCB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCB0" } ] } ] }, { "uniprot_ac": "F1NXP2", "gene_name": "GTF2B", "activity": [ { "ec_number": "2.3.1.48", "activity": "L-lysyl-[histone] + acetyl-CoA = N(6)-acetyl-L-lysyl-[histone] + CoA + H(+).", "evidence": [ { "id": "F1NXP2", "database": "UniProtKB", "url": 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"database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJQ7" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.3.1.48", "ec_name": "L-lysyl-[histone] + acetyl-CoA = N(6)-acetyl-L-lysyl-[histone] + CoA + H(+).", "evidence": [ { "id": "2.3.1.48", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.48" }, { "id": "2.3.1.48", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.3.1.48" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { 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This record is derived from a genomic sequence (NC_052548.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003642300", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003642300" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1P0D2", "url": "https://www.uniprot.org/uniprotkb/F1P0D2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "GSL", "url": "https://www.uniprot.org/uniprotkb/F1P0D2", "locus": {} } ], "crossref": [ { "id": "F1P0D2", "url": "https://alphafold.ebi.ac.uk/entry/F1P0D2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000008518", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000008518", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "417253", "url": 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"id": "IPR050292", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050292", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:417253", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417253", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "TKDYADH", "url": "https://omabrowser.org/oma/group/TKDYADH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1L1RZG8", "url": "https://www.orthodb.org/?gene=A0A1L1RZG8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AEZ4", "url": "https://www.orthodb.org/?gene=A0A8V1AEZ4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1P0D2", "url": "https://www.orthodb.org/?gene=F1P0D2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR20852", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR20852", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR20852:SF43", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR20852:SF43", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00120", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00120", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF03951", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03951", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003642300", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003642300", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "16169", "url": "https://www.rhea-db.org/rhea/16169", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A1L1RZG8", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RZG8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1L1RZG8-1", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RZG8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AEZ4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEZ4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AEZ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEZ4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1P0D2", "url": "https://www.uniprot.org/uniprotkb/F1P0D2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1P0D2-1", "url": "https://www.uniprot.org/uniprotkb/F1P0D2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSVSHSSRLNKLVREQYMRLPQGGLVQVTYVWIDGSGEGVRCKSRTLDKEPKSIEDVPEWNFDGSSTAQAEGSNSDMFLVPVCMFRDPFCLDPNKLVLCEVLKYNRKPAETNLRHTCKKVMDLVKDSHPWFGMEQEYTLLGVNGHPYGWPDNGFPGPQGPYYCGVGADKVYGRDIVESHYKACLYAGVKICGTNAEVMPSQWEFQVGPCEGIEMGDHLWMARFILHRVCEDFGVVATLDPKPMTGNWNGAGCHTNYSTEEMRKEGGLKHIEAAIEKLSKRHDYHICVYDPRGGRDNSRRLTGHHETSNIFEFSAGVANRGASIRIPRQVGQDGFGYFEDRRPAANCDPYAVTEAIMRTTVLNETGVETKEYAEH", "length": 374, "header": "tr|F1P0D2-1|F1P0D2_CHICK Isoform 1 of Glutamine synthetase OS=Gallus gallus OX=9031 GN=GSL PE=1 SV=3 CANONICAL=F1P0D2-1" }, "isoforms": [ { "isoform_ac": "A0A1L1RZG8-1", "url": "https://www.uniprot.org/uniprotkb/F1P0D2/entry#A0A1L1RZG8-1", "sequence": { "sequence": "MPPVPNEADPEVPRMDPRILIFLLYVMILHELVSGWMEYQKQIAKPKKQAGPVWSSRAVAMSVSHSSRLNKLVREQYMRLPQGGLVQVTYVWIDGSGEGVRCKSRTLDKEPKSIEDVPEWNFDGSSTAQAEGSNSDMFLVPVCMFRDPFCLDPNKLVLCEVLKYNRKPAETNLRHTCKKVMDLVKDSHPWFGMEQEYTLLGVNGHPYGWPDNGFPGPQGPYYCGVGADKVYGRDIVESHYKACLYAGVKICGTNAEVMPSQWEFQVGPCEGIEMGDHLWMARFILHRVCEDFGVVATLDPKPMTGNWNGAGCHTNYSTEEMRKEGGLKHIEAAIEKLSKRHDYHICVYDPRGGRDNSRRLTGHHETSNIFEFSAGVANRGASIRIPRQVGQDGFGYFEDRRPAANCDPYAVTEAIMRTTVLNETGVETKEYAEH", "length": 434, "header": "tr|A0A1L1RZG8-1|A0A1L1RZG8_CHICK Computationally mapped isoform of Glutamine synthetase OS=Gallus gallus OX=9031 GN=GSL PE=1 SV=2 CANONICAL=F1P0D2-1" }, "locus": { "chromosome": "17", "start_pos": 2614209, "end_pos": 2593922, "strand": "-", "evidence": [ { "database": 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"evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066801.1", "url": "https://www.ensembl.org/id/ENSGALT00010066801.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040880.1", "url": "https://www.ensembl.org/id/ENSGALP00010040880.1" } ] } }, { "isoform_ac": "F1P0D2-1", "url": "https://www.uniprot.org/uniprotkb/F1P0D2/entry#F1P0D2-1", "sequence": { "sequence": "MSVSHSSRLNKLVREQYMRLPQGGLVQVTYVWIDGSGEGVRCKSRTLDKEPKSIEDVPEWNFDGSSTAQAEGSNSDMFLVPVCMFRDPFCLDPNKLVLCEVLKYNRKPAETNLRHTCKKVMDLVKDSHPWFGMEQEYTLLGVNGHPYGWPDNGFPGPQGPYYCGVGADKVYGRDIVESHYKACLYAGVKICGTNAEVMPSQWEFQVGPCEGIEMGDHLWMARFILHRVCEDFGVVATLDPKPMTGNWNGAGCHTNYSTEEMRKEGGLKHIEAAIEKLSKRHDYHICVYDPRGGRDNSRRLTGHHETSNIFEFSAGVANRGASIRIPRQVGQDGFGYFEDRRPAANCDPYAVTEAIMRTTVLNETGVETKEYAEH", "length": 374, "header": "tr|F1P0D2-1|F1P0D2_CHICK Isoform 1 of Glutamine synthetase OS=Gallus gallus OX=9031 GN=GSL PE=1 SV=3 CANONICAL=F1P0D2-1" }, "locus": { "chromosome": "17", "start_pos": 2614209, "end_pos": 2609109, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066803.1", "url": "https://www.ensembl.org/id/ENSGALT00010066803.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040882.1", "url": "https://www.ensembl.org/id/ENSGALP00010040882.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "gga:417253", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417253", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "Q56WN1-1", "protein_name": "Glutamine synthetase cytosolic isozyme 1-1", "gene_name": "GLN1-1", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSLVSDLINLNLSDSTDKIIAEYIWVGGSGMDMRSKARTLPGPVTDPSQLPKWNYDGSSTGQAPGEDSEVILYPQAIFKDPFRRGNNILVMCDAYTPAGEPIPTNKRHAAAKVFSNPDVAAEVPWYGIEQEYTLLQKDVKWPVGWPIGGYPGPQGPYYCGIGADKSFGRDVVDSHYKACLYAGINISGINGEVMPGQWEFQVGPAVGISAADEIWVARYILERITEIAGVVVSFDPKPIPGDWNGAGAHCNYSTKSMREEGGYEIIKKAIDKLGLRHKEHIAAYGEGNERRLTGHHETADINTFLWGVANRGASIRVGRDTEKEGKGYFEDRRPASNMDPYIVTSMIAETTILWNP", "length": 356 }, "evidence": [ { "id": "F1P0D2", "url": "https://omabrowser.org/oma/group/F1P0D2/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "F1P0D2", "url": "https://www.uniprot.org/uniprotkb/F1P0D2" } ], "pmid": "" }, { "name": "glutamine synthetase activity", "id": "GO:0004356", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004356", "evidence": [ { "database": "UniProtKB", "id": "F1P0D2", "url": "https://www.uniprot.org/uniprotkb/F1P0D2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1P0D2", "url": "https://www.uniprot.org/uniprotkb/F1P0D2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "glutamine biosynthetic process", "id": "GO:0006542", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006542", "evidence": [ { "database": "UniProtKB", "id": "F1P0D2", "url": "https://www.uniprot.org/uniprotkb/F1P0D2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 255, "end_pos": 257, "annotation": "n_glycosylation_sequon" }, { "start_pos": 362, "end_pos": 364, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "16169", "name": "", "equation": "L-glutamate + NH4(+) + ATP = L-glutamine + ADP + phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1P0D2-1", "A0A8V0Y7S7-1", "P16580-1" ], "evidence": [ { "id": "16169", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/16169" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A8V0Y7S7", "gene_name": "GLUL", "activity": [ { "ec_number": "6.3.1.2", "activity": "L-glutamate + NH4(+) + ATP = L-glutamine + ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0Y7S7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y7S7" } ] }, { "ec_number": "6.3.1.2", "activity": "", "evidence": [ { "id": "A0A8V0Y7S7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y7S7" } ] } ] }, { "uniprot_ac": "F1P0D2", "gene_name": "GSL", "activity": [ { "ec_number": "6.3.1.2", "activity": "L-glutamate + NH4(+) + ATP = L-glutamine + ADP + phosphate + H(+).", "evidence": [ { "id": "F1P0D2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P0D2" } ] }, { "ec_number": "6.3.1.2", "activity": "", "evidence": [ { "id": "F1P0D2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P0D2" } ] } ] }, { "uniprot_ac": "P16580", "gene_name": "GLUL", "activity": [ { "ec_number": "6.3.1.2", "activity": "L-glutamate + NH4(+) + ATP = L-glutamine + ADP + phosphate + H(+).", "evidence": [ { "id": "P16580", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P16580" } ] }, { "ec_number": "4.1.1.15", "activity": "L-glutamate + H(+) = 4-aminobutanoate + CO2.", "evidence": [ { "id": "P16580", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P16580" } ] }, { "ec_number": "6.3.1.2", "activity": "", "evidence": [ { "id": "P16580", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P16580" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "6.3.1.2", "ec_name": "L-glutamate + NH4(+) + ATP = L-glutamine + ADP + phosphate + H(+).", "evidence": [ { "id": "6.3.1.2", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:6.3.1.2" }, { "id": "6.3.1.2", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=6.3.1.2" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 255, "end_pos": 257 }, { "start_pos": 362, "end_pos": 364 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1NHC9-1", "uniprot_ac": "F1NHC9", "uniprot_id": 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N-acetylglucosamine from UDP-GlcNAc to a serine or threonine residue in extracellular proteins resulting in their modification with a beta-linked N-acetylglucosamine (O-GlcNAc). Specifically glycosylates the Thr residue located between the fifth and sixth conserved cysteines of folded EGF-like domains.", "evidence": [ { "database": "UniProtKB", "id": "F1NHC9", "url": "https://www.uniprot.org/uniprotkb/F1NHC9#function" }, { "database": "UniProtKB", "id": "ARBA00037761", "url": "https://www.uniprot.org/uniprotkb/ARBA00037761#function" }, { "database": "UniProtKB", "id": "A0A3Q2U477", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U477#function" }, { "database": "UniProtKB", "id": "A0A3Q2UB07", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UB07#function" }, { "database": "UniProtKB", "id": "A0A8V0ZCU3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCU3#function" }, { "database": "UniProtKB", "id": "A0A8V0Z5J6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5J6#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NHC9", "url": "https://www.uniprot.org/uniprotkb/F1NHC9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "EOGT", "url": "https://www.uniprot.org/uniprotkb/F1NHC9", "locus": { "chromosome": "12", "start_pos": 15446953, "end_pos": 15475591, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010020005", "url": "https://www.ensembl.org/id/ENSGALG00010020005" } ] } } ], "crossref": [ { "id": "F1NHC9", "url": "https://alphafold.ebi.ac.uk/entry/F1NHC9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000013406", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000013406", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "426961", "url": "https://www.ncbi.nlm.nih.gov/gene/426961", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR007657", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007657", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR049625", "url": "https://www.ebi.ac.uk/interpro/entry/IPR049625", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q2U477", "url": "https://www.orthodb.org/?gene=A0A3Q2U477", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q2UB07", "url": "https://www.orthodb.org/?gene=A0A3Q2UB07", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z5J6", "url": "https://www.orthodb.org/?gene=A0A8V0Z5J6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZCU3", "url": "https://www.orthodb.org/?gene=A0A8V0ZCU3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NHC9", "url": "https://www.orthodb.org/?gene=F1NHC9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR20961", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR20961", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR20961:SF148", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR20961:SF148", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04577", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04577", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "48904", "url": "https://www.rhea-db.org/rhea/48904", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "48908", "url": "https://www.rhea-db.org/rhea/48908", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q2U477", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U477", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2U477-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U477-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2UB07", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UB07", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2UB07-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UB07-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z5J6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5J6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z5J6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5J6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZCU3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCU3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZCU3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCU3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NHC9", "url": "https://www.uniprot.org/uniprotkb/F1NHC9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NHC9-1", "url": "https://www.uniprot.org/uniprotkb/F1NHC9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MFILLMFVLLLQEILANSRDENLTELNSVLEEPTYSYRAINLPAEHIPYFLHNNRHIAGICKQDSRCPYKKYLKKLKSCWGYEKSCKSDYRFSYPVCDYVESGWANDIETAQQIFWKQADFGYIRERLNEMKTHCKPTVTGDSSLTCSQFLQHCRATNLYIDLRTAKRNHERFKEDFFQKGEIGGHCTLDVKAFLAEGQRKSPLQSWFAELQTFTSLNFRPLDDGKCDIVIEKPTYFMKLDAGVNMYHHFCDFVNLYITQHINNSFSTDVNIVMWDTSSYGYGDLFSETWKAFTDYDIIHLKTFDSKRVCFKEAVFSLLPRMRYGLFYNTPLISGCHGTGLFRAFSQHVLHRLNITQEGPKDGKIRVTILARSTDYRKILNQNELVNALKTVSTLEVKVVDYKYKELEFSEQLRITHNSDIFIGMHGAGLTHLLFLPDWAVVFELYNCEDERCYLDLARLRGIHYITWRKRNKVFPQDQGHHPTLGEHPKFTNYSFDVEEFMYLVLLAANHVSQHSKWPFRF", "length": 522, "header": "tr|F1NHC9-1|F1NHC9_CHICK Isoform 1 of EGF domain-specific O-linked N-acetylglucosamine transferase OS=Gallus gallus OX=9031 GN=EOGT PE=3 SV=4 CANONICAL=F1NHC9-1" }, "isoforms": [ { "isoform_ac": "A0A3Q2U477-1", "url": "https://www.uniprot.org/uniprotkb/F1NHC9/entry#A0A3Q2U477-1", "sequence": { "sequence": "MFILLMFVLLLQEILANSRDENLTELNSVLEEPTYSYRAINLPAEHIPYFLHNNRHIAGICKQDSRCPYKKYLKKLKSCWGYEKSCKSDYRFSYPVCDYVESGWANDIETAQQIFWKQADFGYIRERLNEMKTHCKPTVTGDSSLTCSQFLQHCRATNLYIDLRTAKRNHERFKEDFFQKGEIGGHCTLDVKAFLAEGQRKSPLQSWFAELQTFTSLNFRPLDDGKCDIVIEKPTYFMKLDAGVNMYHHFCDFVNLYITQHINNSFSTDVNIVMWDTSSYGYGDLFSETWKAFTDYDIIHLKTFDSKRVCFKEAVFSLLPRMRYGLFYNTPLISGCHGTGLFRAFSQHVLHRLNITQEGPKDGKIRVTILARSTDYRKILNQNELVNALKTVSTLEVKVVDYKYKELEFSEQLRITHNSDIFIGMHGAGLTHLLFLPDWAVVFELYNCEDERCYLDLARLRGIHYITWRKRNKVFPQDQGHHPTLGEHPKFTNYSFDVEEFMYLVLLAANHVSQHSKWPFRCPAWTSSMKRSHQSRWDNVSSLLISSRLHKTTPTQC", "length": 557, "header": "tr|A0A3Q2U477-1|A0A3Q2U477_CHICK Computationally mapped isoform of EGF domain-specific O-linked N-acetylglucosamine transferase OS=Gallus gallus OX=9031 GN=EOGT PE=3 SV=1 CANONICAL=F1NHC9-1" }, "locus": { "chromosome": "12", "start_pos": 15474534, "end_pos": 15447804, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048368.1", "url": "https://www.ensembl.org/id/ENSGALT00010048368.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028519.1", "url": "https://www.ensembl.org/id/ENSGALP00010028519.1" } ] } }, { "isoform_ac": "A0A3Q2UB07-1", "url": "https://www.uniprot.org/uniprotkb/F1NHC9/entry#A0A3Q2UB07-1", "sequence": { "sequence": "MFILLMFVLLLQEILANSRDENLTELNSVLEEPTYSYRAINLPAEHIPYFLHNNRHIAGICKQDSRCPYKKYLKKLKSCWGYEKSCKSDYRFSYPVCDYVESGWANDIETAQQIFWKQADFGYIRERLNEMKTHCKPTVTGDSSLTCSQFLQHCRATNLYIDLRTAKRNHERFKEDFFQKGEIGGHCTLDVKAFLAEGQRKSPLQSWFAELQTFTSLNFRPLDDGKCDIVIEKPTYFMKLDAGVNMYHHFCDFVNLYITQHINNSFSTDVNIVMWDTSSYGYGDLFSETWKAFTDYDIIHLKTFDSKRVCFKEAVFSLLPRMRYGLFYNTPLISGCHGTGLFRAFSQHVLHRLNITQEGPKLVNALKTVSTLEVKVVDYKYKELEFSEQLRITHNSDIFIGMHGAGLTHLLFLPDWAVVFELYNCEDERCYLDLARLRGIHYITWRKRNKVFPQDQGHHPTLGEHPKFTNYSFDVEEFMYLVLLAANHVSQHSKWPFRVKHDEF", "length": 504, "header": "tr|A0A3Q2UB07-1|A0A3Q2UB07_CHICK Computationally mapped isoform of EGF domain-specific O-linked N-acetylglucosamine transferase OS=Gallus gallus OX=9031 GN=EOGT PE=3 SV=1 CANONICAL=F1NHC9-1" }, "locus": { "chromosome": "12", "start_pos": 15474534, "end_pos": 15460832, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048343.1", "url": "https://www.ensembl.org/id/ENSGALT00010048343.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028504.1", "url": "https://www.ensembl.org/id/ENSGALP00010028504.1" } ] } }, { "isoform_ac": "A0A8V0Z5J6-1", "url": "https://www.uniprot.org/uniprotkb/F1NHC9/entry#A0A8V0Z5J6-1", "sequence": { "sequence": 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"ENSGALP00010028512.1", "url": "https://www.ensembl.org/id/ENSGALP00010028512.1" } ] } }, { "isoform_ac": "A0A8V0ZCU3-1", "url": "https://www.uniprot.org/uniprotkb/F1NHC9/entry#A0A8V0ZCU3-1", "sequence": { "sequence": "MFILLMFVLLLQEILANSRDENLTELNSVLEEPTYSYRAINLPAEHIPYFLHNNRHIAGICKQDSRCPYKKYLKKLKSCWGYEKSCKSDYRFSYPVCDYVESGWANDIETAQQIFWKQADFGYIRERLNEMKTHCKPTVTGDSSLTCSQFLQHCRATNLYIDLRTAKRNHERFKEDFFQKGEIGGHCTLDVKAFLAEGQRKSPLQSWFAELQTFTSLNFRPLDDGKCDIVIEKPTYFMKLDAEVLICTIISVTSSIFILHSILIIPSVLMSTSSCGTLSYGYGDLFSETWKAFTDYDIIHLKTFDSKRVCFKEAVFSLLPRMRYGLFYNTPLISGCHGTGLFRAFSQHVLHRLNITQEGPKDGKIRVTILARSTDYRKILNQNELVNALKTVSTLEVKVVDYKYKELEFSEQLRITHNSDIFIGMHGAGLTHLLFLPDWAVVFELYNCEDERCYLDLARLRGIHYITWRKRNKVFPQDQGHHPTLGEHPKFTNYSFDVEEFMYLVLLAANHVSQHSKWPFRVKHDEF", "length": 527, "header": "tr|A0A8V0ZCU3-1|A0A8V0ZCU3_CHICK Computationally mapped isoform of EGF domain-specific O-linked N-acetylglucosamine transferase OS=Gallus gallus OX=9031 GN=EOGT PE=3 SV=1 CANONICAL=F1NHC9-1" }, "locus": { "chromosome": "12", "start_pos": 15474534, "end_pos": 15460832, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048351.1", "url": "https://www.ensembl.org/id/ENSGALT00010048351.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028510.1", "url": "https://www.ensembl.org/id/ENSGALP00010028510.1" } ] } }, { "isoform_ac": "F1NHC9-1", "url": "https://www.uniprot.org/uniprotkb/F1NHC9/entry#F1NHC9-1", "sequence": { "sequence": "MFILLMFVLLLQEILANSRDENLTELNSVLEEPTYSYRAINLPAEHIPYFLHNNRHIAGICKQDSRCPYKKYLKKLKSCWGYEKSCKSDYRFSYPVCDYVESGWANDIETAQQIFWKQADFGYIRERLNEMKTHCKPTVTGDSSLTCSQFLQHCRATNLYIDLRTAKRNHERFKEDFFQKGEIGGHCTLDVKAFLAEGQRKSPLQSWFAELQTFTSLNFRPLDDGKCDIVIEKPTYFMKLDAGVNMYHHFCDFVNLYITQHINNSFSTDVNIVMWDTSSYGYGDLFSETWKAFTDYDIIHLKTFDSKRVCFKEAVFSLLPRMRYGLFYNTPLISGCHGTGLFRAFSQHVLHRLNITQEGPKDGKIRVTILARSTDYRKILNQNELVNALKTVSTLEVKVVDYKYKELEFSEQLRITHNSDIFIGMHGAGLTHLLFLPDWAVVFELYNCEDERCYLDLARLRGIHYITWRKRNKVFPQDQGHHPTLGEHPKFTNYSFDVEEFMYLVLLAANHVSQHSKWPFRF", "length": 522, "header": "tr|F1NHC9-1|F1NHC9_CHICK Isoform 1 of EGF domain-specific O-linked N-acetylglucosamine transferase OS=Gallus gallus OX=9031 GN=EOGT PE=3 SV=4 CANONICAL=F1NHC9-1" }, "locus": { "chromosome": "12", "start_pos": 15474534, "end_pos": 15460468, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048363.1", "url": "https://www.ensembl.org/id/ENSGALT00010048363.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028516.1", "url": "https://www.ensembl.org/id/ENSGALP00010028516.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "protein O-acetylglucosaminyltransferase activity", "id": "GO:0097363", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097363", "evidence": [ { "database": "UniProtKB", "id": "F1NHC9", "url": "https://www.uniprot.org/uniprotkb/F1NHC9" } ], "pmid": "" }, { "name": "glycosyltransferase activity", "id": "GO:0016757", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016757", "evidence": [ { "database": "UniProtKB", "id": "F1NHC9", "url": "https://www.uniprot.org/uniprotkb/F1NHC9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "endoplasmic reticulum lumen", "id": "GO:0005788", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005788", "evidence": [ { "database": "UniProtKB", "id": "F1NHC9", "url": "https://www.uniprot.org/uniprotkb/F1NHC9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "protein O-linked glycosylation", "id": "GO:0006493", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006493", "evidence": [ { "database": "UniProtKB", "id": "F1NHC9", "url": "https://www.uniprot.org/uniprotkb/F1NHC9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 22, "end_pos": 24, "annotation": "n_glycosylation_sequon" }, { "start_pos": 263, "end_pos": 265, "annotation": "n_glycosylation_sequon" }, { "start_pos": 354, "end_pos": 356, "annotation": "n_glycosylation_sequon" }, { "start_pos": 493, "end_pos": 495, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "48904", "name": "", "equation": "L-seryl-[protein] + UDP-N-acetyl-alpha-D-glucosamine = 3-O-(N-acetyl-beta-D-glucosaminyl)-L-seryl-[protein] + UDP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q5NDL3-1", "F1NHC9-1" ], "evidence": [ { "id": "48904", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/48904" } ] }, { "id": "48908", "name": "", "equation": "L-threonyl-[protein] + UDP-N-acetyl-alpha-D-glucosamine = 3-O-(N-acetyl-beta-D-glucosaminyl)-L-threonyl-[protein] + UDP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q5NDL3-1", "F1NHC9-1" ], "evidence": [ { "id": "48908", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/48908" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "F1NHC9", "gene_name": "EOGT", "activity": [ { "ec_number": "2.4.1.255", "activity": "L-threonyl-[protein] + UDP-N-acetyl-alpha-D-glucosamine = 3-O-(N-acetyl-beta-D-glucosaminyl)-L-threonyl-[protein] + UDP + H(+).", "evidence": [ { "id": "F1NHC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NHC9" } ] }, { "ec_number": "2.4.1.255", "activity": "", "evidence": [ { "id": "F1NHC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NHC9" } ] } ] }, { "uniprot_ac": "Q5NDL3", "gene_name": "EOGT", "activity": [ { "ec_number": "2.4.1.255", "activity": "L-threonyl-[protein] + UDP-N-acetyl-alpha-D-glucosamine = 3-O-(N-acetyl-beta-D-glucosaminyl)-L-threonyl-[protein] + UDP + H(+).", "evidence": [ { "id": "Q5NDL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5NDL3" } ] }, { "ec_number": "2.4.1.255", "activity": "", "evidence": [ { "id": "Q5NDL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5NDL3" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1NHC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NHC9" }, { "id": "PF04577", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04577" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Glycosyltransferase 61 catalytic", "eco_id": "ECO_0000259", "start_pos": 336, "end_pos": 442, "start_aa": "Cys", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.4.1.255", "ec_name": "L-threonyl-[protein] + UDP-N-acetyl-alpha-D-glucosamine = 3-O-(N-acetyl-beta-D-glucosaminyl)-L-threonyl-[protein] + UDP + H(+).", "evidence": [ { "id": "2.4.1.255", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.1.255" }, { "id": "2.4.1.255", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.4.1.255" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 22, "end_pos": 24 }, { "start_pos": 263, "end_pos": 265 }, { "start_pos": 354, "end_pos": 356 }, { "start_pos": 493, "end_pos": 495 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": 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"summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046791629" }, "gene_names": [ { "name": "MRPS27", "type": "recommended", "evidence": [ { "id": "A0A8V0YE73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE73" } ] }, { "name": "MRPS27", "type": "synonym", "evidence": [ { "id": "XP_046791629", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046791629" } ] } ], "protein_names": [ { "name": "Small ribosomal subunit protein mS27", "type": "recommended", "evidence": [ { "id": "A0A8V0YE73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE73/entry#names_and_taxonomy" } ] }, { "name": "28S ribosomal protein S27, mitochondrial isoform X1", "type": "synonym", "evidence": [ { "id": "XP_046791629", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046791629" } ] }, { "name": "28S ribosomal protein S27, mitochondrial", "type": "synonym", "evidence": [ { "id": "A0A8V0YE73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE73/entry#names_and_taxonomy" } ] }, { "name": "Mitochondrial ribosomal protein S27", "type": "synonym", "evidence": [ { "id": "A0A8V0YE73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE73/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_059536) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_046791629", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046791629" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YE73", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE73" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MRPS27", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE73", "locus": { "chromosome": "Z", "start_pos": 25866655, "end_pos": 25819642, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010011649", "url": "https://www.ensembl.org/id/ENSGALG00010011649" } ] } } ], "crossref": [ { "id": "A0A8V0YE73", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YE73", "database": 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"categories": [ "Protein Classification" ] }, { "id": "A0A8V0YAG7", "url": "https://www.orthodb.org/?gene=A0A8V0YAG7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YAH2", "url": "https://www.orthodb.org/?gene=A0A8V0YAH2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YAH8", "url": "https://www.orthodb.org/?gene=A0A8V0YAH8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YE68", "url": "https://www.orthodb.org/?gene=A0A8V0YE68", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YE73", "url": "https://www.orthodb.org/?gene=A0A8V0YE73", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YIV2", "url": "https://www.orthodb.org/?gene=A0A8V0YIV2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YIV7", "url": "https://www.orthodb.org/?gene=A0A8V0YIV7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YIW2", "url": "https://www.orthodb.org/?gene=A0A8V0YIW2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21393", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21393", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21393:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21393:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10037", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10037", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-5389840", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5389840", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-5419276", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5419276", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9937383", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9937383", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_046791629", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046791629", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Y5S8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5S8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y5S8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5S8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YAG7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAG7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YAG7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAG7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YAH2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAH2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YAH2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAH2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YAH8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAH8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YAH8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAH8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YE68", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE68", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YE68-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE68-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YE73", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE73", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YE73-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE73-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YIV2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YIV2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YIV7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YIV7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YIW2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIW2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YIW2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIW2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAASVLVRGALRGGKVVGAAAGRRSLLSAAYVDSSKWESRQKEEHNLADLANLMDRTYERKLPVSSLTIGRFVDNISSREEVDQAEYYLYKFRHSPNCWYLRDWTIHSWIRQCLKHGAQDKALYTLKNKVQYGIFPDNFTFNILLDYFIKQKKYEDAMSVVTEIMLQESFDEFSTQLLSLYVIYQYLATKSERTWEEERNLGASLVLTGLKQTSTVGFSSQLYGYAFLGKVELNKGLRAVYDLMPLMWTPGYLNRALQVMENVASLPGDSKICQEAVDVLETVLRSVLEAKPGPEPSEEAKEVEQKSEYAESEKTEQSKIPEYYSQFKELYSKLHSLGKVESESLLTLTTQLVKEKLPACEVEDIAKHEQKLKEWEQEQAFLIERERELREKAKQELEARKLAKASA", "length": 407, "header": "tr|A0A8V0YE73-1|A0A8V0YE73_CHICK Isoform 1 of Small ribosomal subunit protein mS27 OS=Gallus gallus OX=9031 GN=MRPS27 PE=1 SV=1 CANONICAL=A0A8V0YE73-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Y5S8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE73/entry#A0A8V0Y5S8-1", "sequence": { "sequence": "MAASVLVRGALRGGKVVGAAAGRRSLLSAAYVDSSKWESRQKEEHNLADLANLMDRTYERKLPVSSLTIGRFVDNISSREEVDQAEYYLYKFRHSPNCWYLRDWTIHSWIRQCLKHGAQDKALYTLKNKVQYGIFPDNFTFNILLDYFIKQKKYEDAMSVVTEIMLQESFDEFSTQLLSLYVIYQYLATKSERTWEEERNLGASLVLTGLKQTSTVGFSSQLYGYAFLGKVELNKGLRAVYDLMPLMWTPGYLNRALQVMENVASLPGDSKICQEAVDVLETVLRSVLEAKPGPEPSEEAKEVEQKSEYAESEKTEQSKIPEYYSQFKAFRDVVMSTLISIKQTTLSVLISKVSEKSEYKEIHSSYMKRRYPTELYSKLHSLGKVESESLLTLTTQLVKEKLPACEVEDIAKHEQKLKEWEQEQAFLIERERELREKAKQELEARKLAKASA", "length": 452, "header": "tr|A0A8V0Y5S8-1|A0A8V0Y5S8_CHICK Computationally mapped isoform of Small ribosomal subunit protein mS27 OS=Gallus gallus OX=9031 GN=MRPS27 PE=1 SV=1 CANONICAL=A0A8V0YE73-1" }, "locus": { "chromosome": "Z", "start_pos": 25866179, "end_pos": 25819855, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027875.1", "url": "https://www.ensembl.org/id/ENSGALT00010027875.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015991.1", "url": "https://www.ensembl.org/id/ENSGALP00010015991.1" } ] } }, { "isoform_ac": "A0A8V0YAG7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE73/entry#A0A8V0YAG7-1", "sequence": { "sequence": "MAASVLVRGALRGGKVVGAAAGRRSLLSAAYVDSSKWESRQKEEHNLADLANLMDRTYERKLPVSSLTIGRFVDNISSREEVDQAEYYLYKCTVSNLF", "length": 98, "header": "tr|A0A8V0YAG7-1|A0A8V0YAG7_CHICK Computationally mapped isoform of Mitochondrial ribosomal protein S27 OS=Gallus gallus OX=9031 GN=MRPS27 PE=1 SV=1 CANONICAL=A0A8V0YE73-1" }, "locus": { "chromosome": "Z", "start_pos": 25829735, "end_pos": 25819855, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027854.1", "url": "https://www.ensembl.org/id/ENSGALT00010027854.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015975.1", "url": "https://www.ensembl.org/id/ENSGALP00010015975.1" } ] } }, { "isoform_ac": "A0A8V0YAH2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE73/entry#A0A8V0YAH2-1", "sequence": { "sequence": "MAASVLVRGALRGGKVVGAAAGRRSLLSAAYVDSSKWESRQKEEHNLADLANLMDRTYERKLPVSSLTIGRFVDNISSREEVDQAEYYLYKRYVKAALDCITT", "length": 103, "header": "tr|A0A8V0YAH2-1|A0A8V0YAH2_CHICK Computationally mapped isoform of Mitochondrial ribosomal protein S27 OS=Gallus gallus OX=9031 GN=MRPS27 PE=1 SV=1 CANONICAL=A0A8V0YE73-1" }, "locus": { "chromosome": "Z", "start_pos": 25848178, "end_pos": 25819855, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027859.1", "url": "https://www.ensembl.org/id/ENSGALT00010027859.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015980.1", "url": "https://www.ensembl.org/id/ENSGALP00010015980.1" } ] } }, { "isoform_ac": "A0A8V0YAH8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE73/entry#A0A8V0YAH8-1", "sequence": { "sequence": "MNLKEESGGEIQWLFSSRRTDETDLANLMDRTYERKLPVSSLTIGRFVDNISSREEVDQAEYYLYKFRHSPNCWYLRDWTIHSWIRQCLKHGAQDKALYTLKNKVQYGIFPDNFTFNILLDYFIKQKKYEDAMSVVTEIMLQESFDEFSTQLLSLYVIYQYLATKSERTWEEERNLGASLVLTGLKQTSTVGFSSQLYGYAFLGKVELNKGLRAVYDLMPLMWTPGYLNRALQVMENVASLPGDSKICQEAVDVLETVLRSVLEAKPGPEPSEEAKEVEQKSEYAESEKTEQSKIPEYYSQFKELYSKLHSLGKVESESLLTLTTQLVKEKLPACEVEDIAKHEQKLKEWEQEQAFLIERERELREKAKQELEARKLAKASA", "length": 382, "header": "tr|A0A8V0YAH8-1|A0A8V0YAH8_CHICK Computationally mapped isoform of Small ribosomal subunit protein mS27 OS=Gallus gallus OX=9031 GN=MRPS27 PE=1 SV=1 CANONICAL=A0A8V0YE73-1" }, "locus": { "chromosome": "Z", "start_pos": 25866179, "end_pos": 25821825, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027865.1", "url": "https://www.ensembl.org/id/ENSGALT00010027865.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015985.1", "url": "https://www.ensembl.org/id/ENSGALP00010015985.1" } ] } }, { "isoform_ac": "A0A8V0YE68-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE73/entry#A0A8V0YE68-1", "sequence": { "sequence": "MVLKGFKKKKKKSTHVKELSITTLGRRSLLSAAYVDSSKWESRQKEEHNLADLANLMDRTYERKLPVSSLTIGRFVDNISSREEVDQAEYYLYKFRHSPNCWYLRDWTIHSWIRQCLKHGAQDKALYTLKNKVQYGIFPDNFTFNILLDYFIKQKKYEDAMSVVTEIMLQESFDEFSTQLLSLYVIYQYLATKSERTWEEERNLGASLVLTGLKQTSTVGFSSQLYGYAFLGKVELNKGLRAVYDLMPLMWTPGYLNRALQVMENVASLPGDSKICQEAVDVLETVLRSVLEAKPGPEPSEEAKEVEQKSEYAESEKTEQSKIPEYYSQFKELYSKLHSLGKVESESLLTLTTQLVKEKLPACEVEDIAKHEQKLKEWEQEQAFLIERERELREKAKQELEARKLAKASA", "length": 410, "header": "tr|A0A8V0YE68-1|A0A8V0YE68_CHICK Computationally mapped isoform of Small ribosomal subunit protein mS27 OS=Gallus gallus OX=9031 GN=MRPS27 PE=1 SV=1 CANONICAL=A0A8V0YE73-1" }, "locus": { "chromosome": "Z", "start_pos": 25866179, "end_pos": 25820229, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027863.1", "url": "https://www.ensembl.org/id/ENSGALT00010027863.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015984.1", "url": "https://www.ensembl.org/id/ENSGALP00010015984.1" } ] } }, { "isoform_ac": "A0A8V0YE73-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE73/entry#A0A8V0YE73-1", "sequence": { "sequence": "MAASVLVRGALRGGKVVGAAAGRRSLLSAAYVDSSKWESRQKEEHNLADLANLMDRTYERKLPVSSLTIGRFVDNISSREEVDQAEYYLYKFRHSPNCWYLRDWTIHSWIRQCLKHGAQDKALYTLKNKVQYGIFPDNFTFNILLDYFIKQKKYEDAMSVVTEIMLQESFDEFSTQLLSLYVIYQYLATKSERTWEEERNLGASLVLTGLKQTSTVGFSSQLYGYAFLGKVELNKGLRAVYDLMPLMWTPGYLNRALQVMENVASLPGDSKICQEAVDVLETVLRSVLEAKPGPEPSEEAKEVEQKSEYAESEKTEQSKIPEYYSQFKELYSKLHSLGKVESESLLTLTTQLVKEKLPACEVEDIAKHEQKLKEWEQEQAFLIERERELREKAKQELEARKLAKASA", "length": 407, "header": "tr|A0A8V0YE73-1|A0A8V0YE73_CHICK Isoform 1 of Small ribosomal subunit protein mS27 OS=Gallus gallus OX=9031 GN=MRPS27 PE=1 SV=1 CANONICAL=A0A8V0YE73-1" }, "locus": { "chromosome": "Z", "start_pos": 25866179, "end_pos": 25819855, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027872.1", "url": "https://www.ensembl.org/id/ENSGALT00010027872.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015989.1", "url": "https://www.ensembl.org/id/ENSGALP00010015989.1" } ] } }, { "isoform_ac": "A0A8V0YIV2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE73/entry#A0A8V0YIV2-1", "sequence": { "sequence": "MAASVLVRGALRGGKVVGAAAGRRSLLSAAYVDSSKWESRQKEEHNLADLANLMDRTYERKLPVSSLTIGRFVDNISSREEVDQAEYYLYNCVSKQQEVK", "length": 100, "header": "tr|A0A8V0YIV2-1|A0A8V0YIV2_CHICK Computationally mapped isoform of Mitochondrial ribosomal protein S27 OS=Gallus gallus OX=9031 GN=MRPS27 PE=1 SV=1 CANONICAL=A0A8V0YE73-1" }, "locus": { "chromosome": "Z", "start_pos": 25843620, "end_pos": 25819855, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027856.1", "url": "https://www.ensembl.org/id/ENSGALT00010027856.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015977.1", "url": "https://www.ensembl.org/id/ENSGALP00010015977.1" } ] } }, { "isoform_ac": "A0A8V0YIV7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE73/entry#A0A8V0YIV7-1", "sequence": { "sequence": "MASDLANLMDRTYERKLPVSSLTIGRFVDNISSREEVDQAEYYLYKFRHSPNCWYLRDWTIHSWIRQCLKHGAQDKALYTLKNKVQYGIFPDNFTFNILLDYFIKQKKYEDAMSVVTEIMLQESFDEFSTQLLSLYVIYQYLATKSERTWEEERNLGASLVLTGLKQTSTVGFSSQLYGYAFLGKVELNKGLRAVYDLMPLMWTPGYLNRALQVMENVASLPGDSKICQEAVDVLETVLRSVLEAKPGPEPSEEAKEVEQKSEYAESEKTEQSKIPEYYSQFKELYSKLHSLGKVESESLLTLTTQLVKEKLPACEVEDIAKHEQKLKEWEQEQAFLIERERELREKAKQELEARKLAKASA", "length": 362, "header": "tr|A0A8V0YIV7-1|A0A8V0YIV7_CHICK Computationally mapped isoform of Small ribosomal subunit protein mS27 OS=Gallus gallus OX=9031 GN=MRPS27 PE=1 SV=1 CANONICAL=A0A8V0YE73-1" }, "locus": { "chromosome": "Z", "start_pos": 25866179, "end_pos": 25822520, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027861.1", "url": "https://www.ensembl.org/id/ENSGALT00010027861.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015982.1", "url": "https://www.ensembl.org/id/ENSGALP00010015982.1" } ] } }, { "isoform_ac": "A0A8V0YIW2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE73/entry#A0A8V0YIW2-1", "sequence": { "sequence": "MWTAQNGKADKKRSITWASKQVLDVISSDLEGKGEYFPNCYPVGNKKLSFTDLANLMDRTYERKLPVSSLTIGRFVDNISSREEVDQAEYYLYKFRHSPNCWYLRDWTIHSWIRQCLKHGAQDKALYTLKNKVQYGIFPDNFTFNILLDYFIKQKKYEDAMSVVTEIMLQESFDEFSTQLLSLYVIYQYLATKSERTWEEERNLGASLVLTGLKQTSTVGFSSQLYGYAFLGKVELNKGLRAVYDLMPLMWTPGYLNRALQVMENVASLPGDSKICQEAVDVLETVLRSVLEAKPGPEPSEEAKEVEQKSEYAESEKTEQSKIPEYYSQFKELYSKLHSLGKVESESLLTLTTQLVKEKLPACEVEDIAKHEQKLKEWEQEQAFLIERERELREKAKQELEARKLAKASA", "length": 410, "header": "tr|A0A8V0YIW2-1|A0A8V0YIW2_CHICK Computationally mapped isoform of Small ribosomal subunit protein mS27 OS=Gallus gallus OX=9031 GN=MRPS27 PE=1 SV=1 CANONICAL=A0A8V0YE73-1" }, "locus": { "chromosome": "Z", "start_pos": 25866179, "end_pos": 25821082, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027868.1", "url": "https://www.ensembl.org/id/ENSGALT00010027868.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015987.1", "url": "https://www.ensembl.org/id/ENSGALP00010015987.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-5389840", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5389840", "resource": "Reactome", "description": "Mitochondrial translation elongation" }, { "id": "R-GGA-5419276", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5419276", "resource": "Reactome", "description": "Mitochondrial translation termination" }, { "id": "R-GGA-9937383", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9937383", "resource": "Reactome", "description": "Mitochondrial ribosome-associated quality control" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "mitochondrial small ribosomal subunit", "id": "GO:0005763", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005763", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YE73", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE73" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YE73", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE73" } ], "pmid": "" }, { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YE73", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE73" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "regulation of translation", "id": "GO:0006417", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006417", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YE73", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE73" } ], "pmid": "" }, { "name": "cell population proliferation", "id": "GO:0008283", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008283", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YE73", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE73" } ], "pmid": "" }, { "name": "mitochondrial translation", "id": "GO:0032543", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032543", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YE73", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE73" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "tRNA binding", "id": "GO:0000049", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000049", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YE73", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE73" } ], "pmid": "" }, { "name": "rRNA binding", "id": "GO:0019843", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019843", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YE73", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE73" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 138, "end_pos": 140, "annotation": "n_glycosylation_sequon" }, { "start_pos": 75, "end_pos": 77, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 138, "end_pos": 140 }, { "start_pos": 75, "end_pos": 77 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YDI4-1", "uniprot_ac": "A0A8V0YDI4", "uniprot_id": "A0A8V0YDI4_CHICK", "mass": { "chemical_mass": 80255.0, "monoisotopic_mass": 80255.0 }, "refseq": { "ac": "XP_004935487", "name": "consortin", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004935487" }, "gene_names": [ { "name": "CNST", "type": "recommended", "evidence": [ { "id": "A0A8V0YDI4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDI4" } ] }, { "name": "CNST", "type": "synonym", "evidence": [ { "id": "XP_004935487", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004935487" } ] } ], "protein_names": [ { "name": "Consortin, connexin sorting protein", "type": "synonym", "evidence": [ { "id": "A0A8V0YDI4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDI4/entry#names_and_taxonomy" } ] }, { "name": "consortin", "type": "synonym", "evidence": [ { "id": "XP_004935487", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004935487" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052534.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_004935487.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004935487", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004935487" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YDI4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDI4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CNST", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDI4", "locus": { "chromosome": "3", "start_pos": 33564470, "end_pos": 33611998, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010010338", "url": "https://www.ensembl.org/id/ENSGALG00010010338" } ] } } ], "crossref": [ { "id": "A0A8V0YDI4", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YDI4", "database": "AlphaFoldDB", "categories": [] }, { "id": "421487", "url": "https://www.ncbi.nlm.nih.gov/gene/421487", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR028129", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028129", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042318", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042318", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR054132", "url": "https://www.ebi.ac.uk/interpro/entry/IPR054132", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:421487", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:421487", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "AKFCTTH", "url": "https://omabrowser.org/oma/group/AKFCTTH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y8V3", "url": "https://www.orthodb.org/?gene=A0A8V0Y8V3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YDI4", "url": "https://www.orthodb.org/?gene=A0A8V0YDI4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR28581", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28581", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR28581:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28581:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15281", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15281", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF22883", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22883", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_004935487", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004935487", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Y8V3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y8V3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y8V3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y8V3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YDI4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDI4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YDI4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDI4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDDREFPPNDLQIISKDSLPADYRAERLTSHLVSSADENENQLDNDGNDVLTSSRIAMGRQDEGEQDSINNNENMDSGDCTPGYKESETERRSVNVHMDPQLEEKPITEKQPGGKRSPRSKRSSSKKSKGVPSVGTTAIKEENTLVTHTDSVHSEGAVEATENSHQKEQKQTLQSLFSLLREEVEQMDSKTLPLCLHQIAETYFQEEEYEKAMKFIQLERLYHEQLLANLSSIQEQWERKWKAAVSSPVRTLRNSAKELSSEELEKLTKVCSSHQQPQAPKNKPVVAENTSESGCLLKLIGSENVKEREAAAFKSGTETCPGIRPKKEDQQPSTRPSDEKQTEEQKEAVSLSVAAGKDHMEEQHRSAESALEPHTQSTGTVGRPSPGCLSSGDAGKDNSLLLRERQISKDAEKIEETAGEPGVKFSPGPMVDALVLTDADYMPADLVSTDKDAQADKNLLRSKLVASSSEIATGQLGNSDLNQQQKRPDDGDDEESPPDRTASSTCSESSKVSEHESTARSRVCKELQRAAGQEEKVKSEEREDVYLRFLNGNIIDTEESFANLANQEEFDTVPDISPERASYNSLEALSLDDSFSSLDELARRIEIAEIAPAEGLVSILKKRDDRDGKTVAQVQQRQTKRRVRFQEMEDTFDQDEVAGGSCILLVLLCIATVFLSIGGTALYCTFGDMESPVCTEFAANMDFYYTQILQRVEELKHWIAFS", "length": 722, "header": "tr|A0A8V0YDI4-1|A0A8V0YDI4_CHICK Isoform 1 of Consortin, connexin sorting protein OS=Gallus gallus OX=9031 GN=CNST PE=4 SV=1 CANONICAL=A0A8V0YDI4-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Y8V3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDI4/entry#A0A8V0Y8V3-1", "sequence": { "sequence": "MAAPQPVLGLKISERGLSGSTSNALMDDREFPPNDLQIISKDSLPADYRAERLTSHLVSSADENENQLDNDGNDVLTSSRIAMGRQDEGEQDSINNNENMDSGDCTPGYKESETERRSVNVHMDPQLEEKPITEKQPGGKRSPRSKRSSSKKSKGVPSVGTTAIKEENTLVTHTDSVHSEGAVEATENSHQKEQKQTLQSLFSLLREEVEQMDSKTLPLCLHQIAETYFQEEEYEKAMKFIQLERLYHEQLLANLSSIQEQWERKWKAAVSSPVRTLRNSAKELSSEELEKLTKVCSSHQQPQAPKNKPVVAENTSESGCLLKLIGSENVKEREAAAFKSGTETCPGIRPKKEDQQPSTRPSDEKQTEEQKEAVSLSVAAGKDHMEEQHRSAESALEPHTQSTGTVGRPSPGCLSSGDAGKDNSLLLRERQISKDAEKIEETAGEPGVKFSPGPMVDALVLTDADYMPADLVSTDKDAQADKNLLRSKLVASSSEIATGQLGNSDLNQQQKRPDDGDDEESPPDRTASSTCSESSKVSEHESTARSRVCKELQRAAGQEEKVKSEEREDVYLRFLNGNIIDTEESFANLANQEEFDTVPDISPERASYNSLEALSLDDSFSSLDELARRIEIAEIAPAEGLVSILKKRDDRDGKTVAQVQQRQTKRRVRFQEMEDTFDQDEVAGGSCILLVLLCIATVFLSIGGTALYCTFGDMESPVCTEFAANMDFYYTQILQRVEELKHWIAFS", "length": 747, "header": "tr|A0A8V0Y8V3-1|A0A8V0Y8V3_CHICK Computationally mapped isoform of Consortin, connexin sorting protein OS=Gallus gallus OX=9031 GN=CNST PE=4 SV=1 CANONICAL=A0A8V0YDI4-1" }, "locus": { "chromosome": "3", "start_pos": 33600582, "end_pos": 33566547, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010024715.1", "url": "https://www.ensembl.org/id/ENSGALT00010024715.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010014019.1", "url": "https://www.ensembl.org/id/ENSGALP00010014019.1" } ] } }, { "isoform_ac": "A0A8V0YDI4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDI4/entry#A0A8V0YDI4-1", "sequence": { "sequence": "MDDREFPPNDLQIISKDSLPADYRAERLTSHLVSSADENENQLDNDGNDVLTSSRIAMGRQDEGEQDSINNNENMDSGDCTPGYKESETERRSVNVHMDPQLEEKPITEKQPGGKRSPRSKRSSSKKSKGVPSVGTTAIKEENTLVTHTDSVHSEGAVEATENSHQKEQKQTLQSLFSLLREEVEQMDSKTLPLCLHQIAETYFQEEEYEKAMKFIQLERLYHEQLLANLSSIQEQWERKWKAAVSSPVRTLRNSAKELSSEELEKLTKVCSSHQQPQAPKNKPVVAENTSESGCLLKLIGSENVKEREAAAFKSGTETCPGIRPKKEDQQPSTRPSDEKQTEEQKEAVSLSVAAGKDHMEEQHRSAESALEPHTQSTGTVGRPSPGCLSSGDAGKDNSLLLRERQISKDAEKIEETAGEPGVKFSPGPMVDALVLTDADYMPADLVSTDKDAQADKNLLRSKLVASSSEIATGQLGNSDLNQQQKRPDDGDDEESPPDRTASSTCSESSKVSEHESTARSRVCKELQRAAGQEEKVKSEEREDVYLRFLNGNIIDTEESFANLANQEEFDTVPDISPERASYNSLEALSLDDSFSSLDELARRIEIAEIAPAEGLVSILKKRDDRDGKTVAQVQQRQTKRRVRFQEMEDTFDQDEVAGGSCILLVLLCIATVFLSIGGTALYCTFGDMESPVCTEFAANMDFYYTQILQRVEELKHWIAFS", "length": 722, "header": "tr|A0A8V0YDI4-1|A0A8V0YDI4_CHICK Isoform 1 of Consortin, connexin sorting protein OS=Gallus gallus OX=9031 GN=CNST PE=4 SV=1 CANONICAL=A0A8V0YDI4-1" }, "locus": { "chromosome": "3", "start_pos": 33598493, "end_pos": 33566547, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010024719.1", "url": "https://www.ensembl.org/id/ENSGALT00010024719.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010014022.1", "url": "https://www.ensembl.org/id/ENSGALP00010014022.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:421487", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:421487", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287BRF4-1", "protein_name": "Consortin, connexin sorting protein", "gene_name": "CNST", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDDRETPTYNLQREPQDGCHPGDGVESLVTCLPSASDENENQLDGDGCERLTSSDGAMGKAGVFEQDTLNNNESCSPSCEVAASENSENPSCEVPKDGQAFLGKDKEIPGKRSLKSKRGTVKKIPQGFSSGDTTHLMQENRLHEASHAVSDEEPAEVNANDQLEGPKLILQSLFSLIRGEVEQLDSRALPLFLHQIAESYFQEEDYEKAMKFIQLERLYHEQLLTNLSAIQEQWETKWKTVEPHAVTSLRNSEKGFNGEDFERLTKFCTTHQDPLLSKCKIAAVQKSLGRKCFTQLVVSEDPKERGATAKEPESETCLGMDSGKEGQHNKETRESSPCCNQVDRQADPPGLVVTAGKSHTEEPLCSTEATLELHAQPLESAGSRSGPHSAENACEDNSRLQLAHTEAGQDVAGSEGIAEDAKVSSESVIVPLILPGSDHIPPVLISEGKYSQTRRKELHLPLQDASEALPTDQLENNELTELQQPDLTDSDGKSPQRQTDSQGSENVLCENNQVSDLSTVLPEVYMAPEEQGDKDDQVSKETEDYLNSLLEGCLKDSEDSLLCEDNQEEDSDLQDLSPEEASYSLQESLPSDESSLSLDDLAKRIEIAEVVPAEGLVSILKKRNDTVGDQPAQMQQKPSKRRVRFQEIDDSLDQDEVGSGSCILLVLLCIATVFLSIGGTALYCTFGDLESPVCVDFADNVDFYYTKLLQGMAELKHWIYLS", "length": 722 }, "evidence": [ { "id": "A0A8V0YDI4", "url": "https://omabrowser.org/oma/group/A0A8V0YDI4/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "D3ZKK3-1", "protein_name": "Consortin, connexin sorting protein", "gene_name": "Cnst", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDDSDSPTYSLQIEPQDGCHPGDSVERRVTRLPSVSDENENQLAGDGPALLTTSDGAMGRAAVSEQDSLNNNESCLSSCEAAPRDNSEGPKDDPPSLGEDTKPPGKRSPRAKRGAPKSSAPPGDGVTQMPNAASQAAGEEEAAGVNANDPPKAAALQPLFSLIRGEVEQMDSRALPLFLHQVAETYFQEEDYEKAMKFIQLERLYHEQLLANLSAIQEQWETKWKSVQPSTKKPLRNSEKGFNGEDFEQLAKICTTHQDPLLSKLKIVPVEQSPGKKGFPRVTMSDEPMERGATAKEPEIETCPGTGPSGGRHEEEPQESSPDCPQMNWQTASPDLPGTAGKAHTEAEALPNTTLELHTQSPEAAGSRSGAAAAENACEDDSCVQAPPTEDHPDVARAPKEVPPSEPVAEPFPSGDIAPPGLISGGKYSQTHRKELCLPLQDTFEALPRDQHCNSEVAKPRQPDVTASDGKSAQSQTGLETGPESALCGDRKASDVSTLCPEVCMAPEERGDREEQVSKETEDYLNSLLEGCLKDVEDSLSYESIQDDDDSDLLQDLSPEEASYSLQENLPPEESALSLDDLAKKIEIAEAIPAEGLVSILKKRNDAVGGHPAQMQQKPSKRRVRFQEIDDNLDQDEVGGGSCVLLILLCIATVFLSVGGTALYCTLGDMESPVCTDFADNVDFYYTKLLQGVAGLKHWVYLS", "length": 703 }, "evidence": [ { "id": "A0A8V0YDI4", "url": "https://omabrowser.org/oma/group/A0A8V0YDI4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E1BC04-1", "protein_name": "Consortin, connexin sorting protein", "gene_name": "CNST", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MDDSETPAYNLQIEPQDGCHPGDGVESKVTCLPSASDENENQLDGDGLELLTSSGSAMGKPEVLEQDSLNNNESCTPSCEVAASENSENISCESPKDGQVFLRKDHKIPGSRSPRSKRGTVKKIPQGLSSEDSTPLMQENILHVVTHAVSDEESAEVNANDQLEASKLVLQSLFSLIRGEVEQLDSRALPLCLHQIAESYFQEEDYEKAMKFIQLERLYHEQLLANLSAIQEQWETKWKTVQPHTVTPLRNSEKGFNGEDFERLAKFCATHQDPLLSKDKIAAVQKSLGRKCFTQLIVSEDPKERGATAKELESEICLGMESGKESQHKEETLESSPCCNEMVRQADPRSLPVTARKGHTEEPLCSSEATQELHAQPSESAGSRSSPHSSGNAPEDDSRLQLAQTEACQDVAETERIAKNPKVSSQSVTEPLILPGSDHIPPALISEGKYSQRKELRLPLRDASEALPTDQLENNELNELQQPDLTERDGKSPQGQADSEGSESVLCENNPVSDLSTVLPEVYMAPEEQGDKEEQVSKETDDYLNSLLGGCLKDTEDSLSYEDNQEEDSDFLQDLSPEEASYSLQENLPSDESCLSLDDLAKRIEIAEVVPAEGLVSILKKRNDSVGDRPAQMQQKPSKRRVRFQEIDDSLDQDEVGGGSCILLVLLCIVTVLLSVGGTALYCTFGDMGSPVCTDFADNVDFYYTKLLQGIAELKHWIYLS", "length": 721 }, "evidence": [ { "id": "A0A8V0YDI4", "url": "https://omabrowser.org/oma/group/A0A8V0YDI4/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "G3H7N5-1", "protein_name": "Consortin", "gene_name": "Cnst", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MDDREAPTYRLQIEPQDGCHPGESVERRVTPLPSVSDENENQLDGDRPAGLTGSDSAMGRATVFEQDSLNNNESCLPPCEVAPSETAEQTPCEGPKDDQPSSGQDKKPPGKRSPRAKKGTPKKVPPGDATPLMQTSNAELQAAGEEAAGVNANDPPKAPVPELQPLFSLIRGEVEQMDSRALPLFLHQVAETYFQEEDYEKAMKFIQLERLYHEQLLANLSAIQEQWETKWKAVQPHTVPPLRNSEKGFNGEDFEQLAKICTTHQDPLLAKHKIAPVEKSLGRKCFSRVTVSEEPKERGATAKEPETETCPGMEPSRGQHEEQPQESSPSSHQMDWQAASPSLPVTAGKEPLFSTNANTQSPETARSRSGPDAAESACEDDSCLQEPPTEDHPGVAEDPKGSPPSESVTEPQLSPSGDSIPPVLISEGKYSETHRKELCLPVQGVLEALPRDQPQSSELDESQQPHLPATDGKSPHSQTDLEPGSENALCGDSKASDVRTLCPEVCMAPEEGRDKEDEVSKETEDYLNSLLEGCLKDAEESLSYEDIQDEDSDLLQDLSPEEASYSLQESLPPDESSLSLDDLAKKIEIAEAVPAEGLVSILKKRNDTIGDHPAQMQQKPAKRRVRFQEIDDSLDQDEVGSGSCILLILLCVATVFLSVGGTALYCTVGDMQSPVCTDFADNVDFYYTKLLQGVAGLKHWVYLS", "length": 704 }, "evidence": [ { "id": "A0A8V0YDI4", "url": "https://omabrowser.org/oma/group/A0A8V0YDI4/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q6PJW8-1", "protein_name": "Consortin", "gene_name": "CNST", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDDSDTPTYYLQIEPQDGCHPGDSVERSVTCLPSASDENENQLDGDGHEHLTSSDSAMGKPQVSEQDSLNNNESCTLSCEVAAGENLQNTLCEASRDEQAFLGKDKKIPGKRSPRSKKGTAKKIPPGLFSGDIAPLMQEKVLSAVTYAVDDEEAAEVNANEQPEAPKLVLQSLFSLIRGEVEQLDSRALPLCLHQIAESYFQEEDYEKAMKFIQLERLYHEQLLANLSAIQEQWETKWKTVQPHTVTALRNSEKGFNGEDFERLTKICATHQDPLLSKHKIAAVEKSQERKCSTQLLVSEDPKEGGATTKESESKTCLGTESSKESQHTVEPLGSSPCCHQMDVQTDSPSLSVTAGKDHMEELLCSAEATLALHTQSSETAGSPSGPDSSEDACEDDSRLQLAQTEACQDVARIEGIAEDPKVFLSSKSKTEPLISPGCDRIPPALISEGKYSQAQRKELRLPLRDASEALPTDQLENNELNELQQPDLTDSDGKSPQAQADSDGSENVLCGNNQISDLGILLPEVCMAPEEKGDKDDQLNKETEDYLNSLLEGCLKDTEDSLSYEDNQDDDSDLLQDLSPEEASYSLQENLPSDESCLSLDDLAKRIEIAEVVPTEGLVSILKKRNDTVGDHPAQMQHKPSKRRVRFQEIDDSLDQDEVGGGSCILLVLLCIATVFLSVGGTALYCTFGDMESPVCTDFADNMDFYYTKLLQGVAELKHWIYLS", "length": 725 }, "evidence": [ { "id": "A0A8V0YDI4", "url": "https://omabrowser.org/oma/group/A0A8V0YDI4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8CBC4-1", "protein_name": "Consortin", "gene_name": "Cnst", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDDSDPPTYSLQIEPQDGCHPGDSVERRVTRLPSVSDENENQLAGDGPAGLTTSEGAMGRATVSEQDSLNNNESFPSSCEAAPTENAENTPSEGPKDDPPSLGQDQKLPAKRSPRAKKSSPKSAPPGDAVPVMQTQNATSQAAGEEEAAGVNANDPPKAPALQPLFSLIRGEVAQMDSRALPLFLHQVAETYFQEEDYEKAMKFIQLERLYHEQLLANLSAIQEQWETKWKAVQPRTVTPLRNSEKGFNGEDFEQLAKICTTHQDPLLSKLKTAPVEPSPERKSLARAIMSEEAVGTEAAAKEPEIETCPSTDPSGDRHEEEPQESSPGCHQMEWQTASPELPGTAGKDHTEELPSSTNATLDLHTQSLETAGSRSGPAAASNACKDSSCVPAPPTEDHCGVARDPKVAPPSESVAEQKLSTGDDGALPGLISEGKYSQAHRKELCLPLQDAFEALPRDQPHSSEVAEPRQPDVTASDGKSAQSQAGLETGPESALCGDRKACDVSTLCLEVCMAPEERRDSEDRVSKETEDYLHSLLERCLKDAEDSLSYEDIQDDDSDLLQDLSPEEASYSLQEDLPPDESTLSLDDLAKKIEIAEAIPAEGLVSILKKRNDTVGSHPAQMQQKPAKRRVRFQEIDDNLEQDEVGGGSCILLILLCIATVFLSVGGTALYCTLGNIESPVCTDFADNVDFYYTKLLQGVAGLKHWVYLS", "length": 711 }, "evidence": [ { "id": "A0A8V0YDI4", "url": "https://omabrowser.org/oma/group/A0A8V0YDI4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "connexin binding", "id": "GO:0071253", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071253", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YDI4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDI4" } ], "pmid": "" }, { "name": "phosphatase binding", "id": "GO:0019902", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019902", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YDI4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDI4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YDI4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDI4" } ], "pmid": "" }, { "name": "transport vesicle", "id": "GO:0030133", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030133", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YDI4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDI4" } ], "pmid": "" }, { "name": "trans-Golgi network", "id": "GO:0005802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005802", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YDI4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDI4" } ], "pmid": "" }, { "name": "protein-containing complex", "id": "GO:0032991", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032991", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YDI4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDI4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "positive regulation of Golgi to plasma membrane protein transport", "id": "GO:0042998", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042998", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YDI4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDI4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 229, "end_pos": 231, "annotation": "n_glycosylation_sequon" }, { "start_pos": 289, "end_pos": 291, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YDI4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDI4" }, { "id": "PF15281", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15281" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Consortin C-terminal", "eco_id": "ECO_0000259", "start_pos": 609, "end_pos": 719, "start_aa": "Glu", "end_aa": "Ile", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0YDI4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDI4" }, { "id": "PF22883", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22883" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Consortin N-terminal", "eco_id": "ECO_0000259", "start_pos": 188, "end_pos": 239, "start_aa": "Asp", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 229, "end_pos": 231 }, { "start_pos": 289, "end_pos": 291 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YEC9-1", "uniprot_ac": "A0A8V0YEC9", "uniprot_id": "A0A8V0YEC9_CHICK", "mass": { "chemical_mass": 74297.0, "monoisotopic_mass": 74297.0 }, "refseq": { "ac": "XP_004937414", "name": "soluble lamin-associated protein of 75 kDa isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004937414" }, "gene_names": [ { "name": "FAM169A", "type": "recommended", "evidence": [ { "id": "A0A8V0YEC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEC9" } ] }, { "name": "FAM169A", "type": "synonym", "evidence": [ { "id": "XP_004937414", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004937414" } ] } ], "protein_names": [ { "name": "Family with sequence similarity 169 member A", "type": "synonym", "evidence": [ { "id": "A0A8V0YEC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEC9/entry#names_and_taxonomy" } ] }, { "name": "soluble lamin-associated protein of 75 kDa isoform X3", "type": "synonym", "evidence": [ { "id": "XP_004937414", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004937414" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052572.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_004937414.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004937414", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004937414" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YEC9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEC9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "FAM169A", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEC9", "locus": { "chromosome": "Z", "start_pos": 24753756, "end_pos": 24720137, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010010625", "url": "https://www.ensembl.org/id/ENSGALG00010010625" } ] } } ], "crossref": [ { "id": "A0A8V0YEC9", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YEC9", "database": "AlphaFoldDB", "categories": [] }, { "id": "431595", "url": "https://www.ncbi.nlm.nih.gov/gene/431595", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR029625", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029625", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:431595", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:431595", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0Y9N7", "url": "https://www.orthodb.org/?gene=A0A8V0Y9N7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YEC5", "url": "https://www.orthodb.org/?gene=A0A8V0YEC5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YEC9", "url": "https://www.orthodb.org/?gene=A0A8V0YEC9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22442", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22442", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22442:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22442:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "R-GGA-9035034", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9035034", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_004937414", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004937414", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Y9N7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9N7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y9N7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9N7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YEC5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEC5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YEC5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEC5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YEC9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEC9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YEC9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEC9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAFPVDMLNGYTHEDLESSAEDYLSELRCGDPNQPEFLSLSDHRKIPISLSTVGFVPLYGGEQTHKVLALFAPEDSLTAVALFLAYQWWSIDDVLRTSVSSREGLQQVNSVGERVVLYVLNRIIYRKNEMERNETPFLCHSSDDYAKIMWRKGEAVGFYSVKPAGAALSPYHTHCYQLPVLDTMFVRKKCRGKDLGLMMLEDFVESFTETTLGLRYPLSSFMYKACKHYFEKYPGDNDLLFEVEGAGFWFQRKSIASVLQREELIKGSQKANVSFQTADHFWQSAANELKTEPETQLSADSQKDQESSDDHASTSEDLSIAQVSIRTRSSHLKRAKTGKNCQDSGPEISQGDEENSPHTSTGRPELPTHTSKCFEVIEEEPEVDVESGEEMITSEEDQSVLETEVHTSPSEKLTEMEGTPSESLNGEVAEETSKTVVMAEEEAANEVLDGESKLQSESQEEPLTLLVPLILESPTKPAEEAVSEKVLNANDSEGLTEESASVEKKGIEEDKQESEEKKSSTENVVALTPKEELSNNGFPNSIKSEAVEEAVSENVVHKPASSVEDQSEEAEQNSQEASVALGQSSLIVVELEGVSFQQPSGQEGQKKQTEEHLEESAEQTEQYTQTAAERAADSSSEEAEIEVPIVDRRNLRRKAKGYKGPPKKKGKPA", "length": 669, "header": "tr|A0A8V0YEC9-1|A0A8V0YEC9_CHICK Isoform 1 of Family with sequence similarity 169 member A OS=Gallus gallus OX=9031 GN=FAM169A PE=1 SV=1 CANONICAL=A0A8V0YEC9-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Y9N7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEC9/entry#A0A8V0Y9N7-1", "sequence": { "sequence": "MISLNVQQNVNNRMAFPVDMLNGYTHEDLESSAEDYLSELRCGDPNQPEFLSLSDHRKIPISLSTVGFVPLYGGEQTHKVLALFAPEDSLTAVALFLAYQWWSIDDVLRTSVSSREGLQQVNSVGERVVLYVLNRIIYRKNEMERNETPFLCHSSDDYAKIMWRKGEAVGFYSVKPAGAALSPYHTHCYQLPVLDTMFVRKKCRGKDLGLMMLEDFVESFTETTLGLRYPLSSFMYKACKHYFEKYPGDNDLLFEVEGAGFWFQRKSIASVLQREELIKGSQKANVSFQTADHFWQSAANELKTEPETQLSADSQKDQESSDDHASTSEDLSIAQVSIRTRSSHLKRAKTGKNCQDSGPEISQGDEENSPHTSTGRPELPTHTSKCFEVIEEEPEVDVESGEEMITSEEDQSVLETEVHTSPSEKLTEMEGTPSESLNGEVAEETSKTVVMAEEEAANEVLDGESKLQSESQEEPLTLLVPLILESPTKPAEEAVSEKVLNANDSEGLTEESASVEKKGIEEDKQESEEKKSSTENVVALTPKEELSNNGFPNSIKSEAVEEAVSENVVHKPASSVEDQSEEAEQNSQEASVALGQSSLIVVELEGVSFQQPSGQEGQKKQTEEHLEESAEQTEQYTQTAAERAADSSSEEAEIEVPIVDRRNLRRKAKGYKGPPKKKGKPA", "length": 682, "header": "tr|A0A8V0Y9N7-1|A0A8V0Y9N7_CHICK Computationally mapped isoform of Family with sequence similarity 169 member A OS=Gallus gallus OX=9031 GN=FAM169A PE=1 SV=1 CANONICAL=A0A8V0YEC9-1" }, "locus": { "chromosome": "Z", "start_pos": 24751715, "end_pos": 24728199, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010025285.1", "url": "https://www.ensembl.org/id/ENSGALT00010025285.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010014318.1", "url": "https://www.ensembl.org/id/ENSGALP00010014318.1" } ] } }, { "isoform_ac": "A0A8V0YEC5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEC9/entry#A0A8V0YEC5-1", "sequence": { "sequence": "MAFPVDMLNGYTHEDLESSAEDYLSELRCGDPNQPEFLSLSDHRKIPISLSTVGFVPLYGGEQTHKVLALFAPEDSLTAVALFLAYQWWSIDDVLRTSVSSREGLQQVNSVGERVVLYVLNRIIYRKNEMERNETPFLCHSSDDYAKIMWRKGEAVGFYSVKPAGAALSPYHTHCYQLPVLDTMFVRKKCRGKDLGLMMLEDFVESFTETTLGLRYPLSSFMYKACKHYFEKYPGDNDLLFEVEGAGFWFQRKSIASVLQREELIKGSQKANVSFQTADHFWQSAANELKTEPETQLSADSQKDQESSDDHASTSEDLSIAQVSIRTRSSHLKRAKTGKNCQDSGPEISQGDEENSPHTSTGRPELPTHTSKCFEVIEEEPEVDVESGEEMITSEEDQSVLETEVHTSPSEKLTEMEGTPSESLNGEVAEETSKTVVMAEEEAANEVLDGESKLQSESQEEPLTLLVPLILESPTKPAEEAVSEKVLNANDSEGLTEESASVEKKGIEEDKQESEEKKSSTENVVALTPKEELSNNGFPNSIKSEANSQEASVALGQSSLIVVELEGVSFQQPSGQEGQKKQTEEHLEESAEQTEQYTQTAAERAADSSSEEAEIEVPIVDRRNLRRKAKGYKGPPKKKGKPA", "length": 643, "header": "tr|A0A8V0YEC5-1|A0A8V0YEC5_CHICK Computationally mapped isoform of Family with sequence similarity 169 member A OS=Gallus gallus OX=9031 GN=FAM169A PE=1 SV=1 CANONICAL=A0A8V0YEC9-1" }, "locus": { "chromosome": "Z", "start_pos": 24751715, "end_pos": 24734789, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010025293.1", "url": "https://www.ensembl.org/id/ENSGALT00010025293.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010014321.1", "url": "https://www.ensembl.org/id/ENSGALP00010014321.1" } ] } }, { "isoform_ac": "A0A8V0YEC9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEC9/entry#A0A8V0YEC9-1", "sequence": { "sequence": "MAFPVDMLNGYTHEDLESSAEDYLSELRCGDPNQPEFLSLSDHRKIPISLSTVGFVPLYGGEQTHKVLALFAPEDSLTAVALFLAYQWWSIDDVLRTSVSSREGLQQVNSVGERVVLYVLNRIIYRKNEMERNETPFLCHSSDDYAKIMWRKGEAVGFYSVKPAGAALSPYHTHCYQLPVLDTMFVRKKCRGKDLGLMMLEDFVESFTETTLGLRYPLSSFMYKACKHYFEKYPGDNDLLFEVEGAGFWFQRKSIASVLQREELIKGSQKANVSFQTADHFWQSAANELKTEPETQLSADSQKDQESSDDHASTSEDLSIAQVSIRTRSSHLKRAKTGKNCQDSGPEISQGDEENSPHTSTGRPELPTHTSKCFEVIEEEPEVDVESGEEMITSEEDQSVLETEVHTSPSEKLTEMEGTPSESLNGEVAEETSKTVVMAEEEAANEVLDGESKLQSESQEEPLTLLVPLILESPTKPAEEAVSEKVLNANDSEGLTEESASVEKKGIEEDKQESEEKKSSTENVVALTPKEELSNNGFPNSIKSEAVEEAVSENVVHKPASSVEDQSEEAEQNSQEASVALGQSSLIVVELEGVSFQQPSGQEGQKKQTEEHLEESAEQTEQYTQTAAERAADSSSEEAEIEVPIVDRRNLRRKAKGYKGPPKKKGKPA", "length": 669, "header": "tr|A0A8V0YEC9-1|A0A8V0YEC9_CHICK Isoform 1 of Family with sequence similarity 169 member A OS=Gallus gallus OX=9031 GN=FAM169A PE=1 SV=1 CANONICAL=A0A8V0YEC9-1" }, "locus": { "chromosome": "Z", "start_pos": 24751715, "end_pos": 24734789, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010025301.1", "url": "https://www.ensembl.org/id/ENSGALT00010025301.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010014326.1", "url": "https://www.ensembl.org/id/ENSGALP00010014326.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:431595", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:431595", "resource": "KEGG Pathway" }, { "id": "R-GGA-9035034", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9035034", "resource": "Reactome", "description": "RHOF GTPase cycle" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nuclear membrane", "id": "GO:0031965", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031965", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YEC9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEC9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 133, "end_pos": 135, "annotation": "n_glycosylation_sequon" }, { "start_pos": 272, "end_pos": 274, "annotation": "n_glycosylation_sequon" }, { "start_pos": 490, "end_pos": 492, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 133, "end_pos": 135 }, { "start_pos": 272, "end_pos": 274 }, { "start_pos": 490, "end_pos": 492 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1NL71-1", "uniprot_ac": "F1NL71", "uniprot_id": "F1NL71_CHICK", "mass": { "chemical_mass": 55660.0, "monoisotopic_mass": 55660.0 }, "refseq": { "ac": "XP_004948594", "name": "PAT complex subunit CCDC47", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004948594" }, "gene_names": [ { "name": "CCDC47", "type": "recommended", "evidence": [ { "id": "F1NL71", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NL71" } ] }, { "name": "CCDC47", "type": "synonym", "evidence": [ { "id": "XP_004948594", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004948594" } ] } ], "protein_names": [ { "name": "PAT complex subunit CCDC47", "type": "recommended", "evidence": [ { "id": "F1NL71", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NL71/entry#names_and_taxonomy" } ] }, { "name": "Coiled-coil domain-containing protein 47", "type": "synonym", "evidence": [ { "id": "F1NL71", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NL71/entry#names_and_taxonomy" } ] }, { "name": "PAT complex subunit CCDC47", "type": "synonym", "evidence": [ { "id": "XP_004948594", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004948594" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052558.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jan 4, 2016 this sequence version replaced XP_004948594.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004948594", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004948594" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NL71", "url": "https://www.uniprot.org/uniprotkb/F1NL71" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CCDC47", "url": "https://www.uniprot.org/uniprotkb/F1NL71", "locus": { "chromosome": "27", "start_pos": 2449009, "end_pos": 2458839, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021666", "url": "https://www.ensembl.org/id/ENSGALG00010021666" } ] } } ], "crossref": [ { "id": "F1NL71", "url": "https://alphafold.ebi.ac.uk/entry/F1NL71", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000000564", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000000564", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "419958", "url": "https://www.ncbi.nlm.nih.gov/gene/419958", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR012879", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012879", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:419958", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419958", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MHLVRDM", "url": "https://omabrowser.org/oma/group/MHLVRDM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZLD8", "url": "https://www.orthodb.org/?gene=A0A8V0ZLD8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NL71", "url": "https://www.orthodb.org/?gene=F1NL71", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12883", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12883", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12883:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12883:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07946", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07946", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_004948594", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004948594", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZLD8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLD8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZLD8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLD8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NL71", "url": "https://www.uniprot.org/uniprotkb/F1NL71", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NL71-1", "url": "https://www.uniprot.org/uniprotkb/F1NL71-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKNLYIFIAVLFIPWSFSLAKYDEFEDGDDIMEYDDNDFAEFEDVNEDAVTESPQRIITTEDDEEEATVELEGQDENQEDFDTDAQEGDTESEPYDDEEFEGYEEKPDASPSKNKDPITIVNVPAHLQNSWESYYMEILMVTGLLAYIMNYIIGKNKNNRLAHAWFNTHRELLESNFALVGDDGTNKEATSTGKLNQENEHIYNLWCSGRVCCEGMLIQLKFLKRQDLLNVLARMMRPACDQVQIKVTMNDDDMDTYVFAVGTRKALVRLQKEMQDLSEFCSDKPKSGAKYGLPDSLAILSEMGEVTEGMMDAKMIHFLTHYADKIESVQFSDQFSGPKLMQEEGQLTKLPETKKTLLFTFNVPGSGNTSPKDMESLLPLMSMVIYSIDKAKKFRLNREGKQKADKNRARVEENFLKLTHVQRQEAAQSRREEKKRAEKERIMNEEDPEKQRRLEEAALRREQKKLEKKQMKMKQIKVKAM", "length": 481, "header": "tr|F1NL71-1|F1NL71_CHICK Isoform 1 of PAT complex subunit CCDC47 OS=Gallus gallus OX=9031 GN=CCDC47 PE=1 SV=2 CANONICAL=F1NL71-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZLD8-1", "url": "https://www.uniprot.org/uniprotkb/F1NL71/entry#A0A8V0ZLD8-1", "sequence": { "sequence": "MNLGRFLAAKMKNLYIFIAVLFIPWSFSLAKYDEFEDGDDIMEYDDNDFAEFEDVNEDAVTESPQRIITTEDDEEEATVELEGQDENQEDFDTDAQEGDTESEPYDDEEFEGYEEKPDASPSKNKDPITIVNVPAHLQNSWESYYMEILMVTGLLAYIMNYIIGKNKNNRLAHAWFNTHRELLESNFALVGDDGTNKEATSTGKLNQENEHIYNLWCSGRVCCEGMLIQLKFLKRQDLLNVLARMMRPACDQVQIKVTMNDDDMDTYVFAVGTRKALVRLQKEMQDLSEFCSDKPKSGAKYGLPDSLAILSEMGEVTEGMMDAKMIHFLTHYADKIESVQFSDQFSGPKLMQEEGQLTKLPETKKTLLFTFNVPGSGNTSPKDMESLLPLMSMVIYSIDKAKKFRLNREGKQKADKNRARVEENFLKLTHVQRQEAAQSRREEKKRAEKERIMNEEDPEKQRRLEEAALRREQKKLEKKQMKMKQIKVKAM", "length": 491, "header": "tr|A0A8V0ZLD8-1|A0A8V0ZLD8_CHICK Computationally mapped isoform of PAT complex subunit CCDC47 OS=Gallus gallus OX=9031 GN=CCDC47 PE=1 SV=1 CANONICAL=F1NL71-1" }, "locus": { "chromosome": "27", "start_pos": 2457603, "end_pos": 2450471, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052633.1", "url": "https://www.ensembl.org/id/ENSGALT00010052633.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031539.1", "url": "https://www.ensembl.org/id/ENSGALP00010031539.1" } ] } }, { "isoform_ac": "F1NL71-1", "url": "https://www.uniprot.org/uniprotkb/F1NL71/entry#F1NL71-1", "sequence": { "sequence": "MKNLYIFIAVLFIPWSFSLAKYDEFEDGDDIMEYDDNDFAEFEDVNEDAVTESPQRIITTEDDEEEATVELEGQDENQEDFDTDAQEGDTESEPYDDEEFEGYEEKPDASPSKNKDPITIVNVPAHLQNSWESYYMEILMVTGLLAYIMNYIIGKNKNNRLAHAWFNTHRELLESNFALVGDDGTNKEATSTGKLNQENEHIYNLWCSGRVCCEGMLIQLKFLKRQDLLNVLARMMRPACDQVQIKVTMNDDDMDTYVFAVGTRKALVRLQKEMQDLSEFCSDKPKSGAKYGLPDSLAILSEMGEVTEGMMDAKMIHFLTHYADKIESVQFSDQFSGPKLMQEEGQLTKLPETKKTLLFTFNVPGSGNTSPKDMESLLPLMSMVIYSIDKAKKFRLNREGKQKADKNRARVEENFLKLTHVQRQEAAQSRREEKKRAEKERIMNEEDPEKQRRLEEAALRREQKKLEKKQMKMKQIKVKAM", "length": 481, "header": "tr|F1NL71-1|F1NL71_CHICK Isoform 1 of PAT complex subunit CCDC47 OS=Gallus gallus OX=9031 GN=CCDC47 PE=1 SV=2 CANONICAL=F1NL71-1" }, "locus": { "chromosome": "27", "start_pos": 2456889, "end_pos": 2450471, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052637.1", "url": "https://www.ensembl.org/id/ENSGALT00010052637.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031543.1", "url": "https://www.ensembl.org/id/ENSGALP00010031543.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:419958", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419958", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "I3LAE8-1", "protein_name": "PAT complex subunit CCDC47", "gene_name": "CCDC47", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MKALHAFCVVLLIFGSFSEAKFDDFEDEEDIVEYDDNDFAEFEDVPEDSVTESPQRVITTEDDEDETTVELEGQDENQEGDFEDADTQEGDTESEPYDDEEFEGYEDKPDTSSSKSKDPITIVDVPAHLQNSWESYYLEILMVTGLLAYIMNYIIGKNKNSRLAQAWFNTHRELLESNFTLVGDDGTNKEATSTGKLNQENEHIYNLWCSGRVCCEGMLIQLRFLKRQDLLNVLARMMRPVSDQVQIKVTMNDEDMDTYVFAVGTRKALVRLQKEMQDLSEFCSDKPKSGAKYGLPDSLAILSEMGEVTEGMMDTKMVHFLTHYADKIESVHFSDQFSGPKIMQEEGQPLKLPDTKRTLLFTFNVPGSGNTYPKDMEALLPLMNMVIYSIDKAKKFRLNREGKQKADKNRARVEENFLKLTHVQRQEAAQSRREEKKRAEKERIMNEEDPEKQRRLEEAALRREQKKLEKKQMKMKQIKVKAM", "length": 483 }, "evidence": [ { "id": "F1NL71", "url": "https://omabrowser.org/oma/group/F1NL71/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q3ZC50-1", "protein_name": "PAT complex subunit CCDC47", "gene_name": "CCDC47", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MKGFHAFCVILLIFGSVSEAKFDDFEDEEDIVEYDDNDFAEFEDVAEDSVTESPQRVIITEDDEDETTVELEGQDESQEGDFEDADTQEGDTESEPYDDEEFEGYEDKPDTSSSKSKDPITIVDVPAHLQNSWESYYLEILMVTGLLAYIMNYIIGKNKNSRLAQAWFNTHRELLESNFTLVGDDGTNKEATSTGKLNQENEHIYNLWCSGRVCCEGMLIQLRFLKRQDLLNVLARMMRPVSDQVQIKVTMNDEDMDTYVFAVGARKALVRLQKEMQDLSEFCSDKPKSGAKYGLPDSLAILSEMGEVTDGMMDTKMLHFLTHYADKIESIHFSDQFSGPKIMQEEGQPLKLPDTKRTLLFTFNVPGSGNTYPKDMEALLPLMNMVIYSIDKAKKFRLNREGKQKADKNRARVEENFLKLTHVQRQEAAQSRREEKKRAEKERIMNEEDPEKQRRLEEAALRREQKKLEKKQMKMKQIKVKAM", "length": 483 }, "evidence": [ { "id": "F1NL71", "url": "https://omabrowser.org/oma/group/F1NL71/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q54VN3-1", "protein_name": "DUF1682 family protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKINKLIIFALFVLLFSLFSLSISQSNDVTTDSEEFINYDGGSEAPEDKIPPPTTTTTDNDKIPSTPTPKKPNNWILESCFILIIIGYIANYFIGSKANRELIQLWGAKLQPVFMSNFSKTGNRGDFTILKVNPSSYSFIATGRNNCFGLQASLDLKKRHDLFSILLDFIGYGNPDRMTLEIAMNKENMDPLVFALVKTKSLKKFKSDNSDVDLFCSKYTGSSINTLSNSFGVLCDTDILPSLLLKQQEIQVINQNENLIELFHFTDHSLINPKYPKALKFVFKIPKASEMDKLVLLTRVALHYIDVVANLELPKNYKAKADKLRDKAKENIEKQAQLERQEEIQKKKFEKKLKEKEAIGKLTPEQQRKKDEKEYQKQLKKRTSGGKTKVILG", "length": 393 }, "evidence": [ { "id": "F1NL71", "url": "https://omabrowser.org/oma/group/F1NL71/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q5U2X6-1", "protein_name": "PAT complex subunit CCDC47", "gene_name": "Ccdc47", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKAFCAFCVVLLVFGSVSEAKFDDFEDEEDIVEYDDNDFAEFEDVVEDSVTESPQRVINTEDDEDEATVELEGQDEGQEGDFEDADTQEGDTESEPYDDEEFEGYEDKPDTSSNKNKDPITIVDVPAHLQNSWESYYLEILMVTGLLAYIMNYIIGKNKNSRLAQAWFNSHRELLESNFTLVGDDGTNKEATSTGKLNQENEHIYNLWCSGRVCCEGMLIQLRFLKRQDLLNVLARMMRPVSDQVQIKVTMNDEDMDTYVFAVGTRKALLRLQKEMQDLSEFCSDKPKSGAKYGLPDSLAILSEMGEVTEGMMDTKMVHFLTHYADKIESVHFSDQFSGPKIMQEEGQPLKLPDTKRTLLFTFNVPGSGNTYPKDMEALLPLMNMVIYSIDKAKKFRLNREGKQKADKNRARVEENFLKLTHVQRQEAAQSRREEKKRAEKERIMNEEDPEKQRRLEEAALRREQKKLEKKQMKMKQIKVKAM", "length": 483 }, "evidence": [ { "id": "F1NL71", "url": "https://omabrowser.org/oma/group/F1NL71/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q96A33-1", "protein_name": "PAT complex subunit CCDC47", "gene_name": "CCDC47", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKAFHTFCVVLLVFGSVSEAKFDDFEDEEDIVEYDDNDFAEFEDVMEDSVTESPQRVIITEDDEDETTVELEGQDENQEGDFEDADTQEGDTESEPYDDEEFEGYEDKPDTSSSKNKDPITIVDVPAHLQNSWESYYLEILMVTGLLAYIMNYIIGKNKNSRLAQAWFNTHRELLESNFTLVGDDGTNKEATSTGKLNQENEHIYNLWCSGRVCCEGMLIQLRFLKRQDLLNVLARMMRPVSDQVQIKVTMNDEDMDTYVFAVGTRKALVRLQKEMQDLSEFCSDKPKSGAKYGLPDSLAILSEMGEVTDGMMDTKMVHFLTHYADKIESVHFSDQFSGPKIMQEEGQPLKLPDTKRTLLFTFNVPGSGNTYPKDMEALLPLMNMVIYSIDKAKKFRLNREGKQKADKNRARVEENFLKLTHVQRQEAAQSRREEKKRAEKERIMNEEDPEKQRRLEEAALRREQKKLEKKQMKMKQIKVKAM", "length": 483 }, "evidence": [ { "id": "F1NL71", "url": "https://omabrowser.org/oma/group/F1NL71/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9D024-1", "protein_name": "PAT complex subunit CCDC47", "gene_name": "Ccdc47", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKAFYAFCVVLLVFGSVSEAKFDDFEDEEDIVEYDDNDFAEFEDVMEDSVTESPQRVISTEDDEDEATVELEGQDESQEGDFEDADTQEGDTESEPYDDEEFEGYEDKPDTSSNKNKDPITIVDVPAHLQNSWESYYLEILMVTGLLAYIMNYIIGKNKNSRLAQAWFNSHRELLESNFTLVGDDGTNKEATSTGKLNQENEHIYNLWCSGRVCCEGMLIQLRFLKRQDLLNVLARMMRPVSDQVQIKVTMNDEDMDTYVFAVGTRKALLRLQKEMQDLSEFCSDKPKSGAKYGLPDSLAILSEMGEVTEGMMDTKMVHFLTHYADKIESVHFSDQFSGPKIMQEEGQPLKLPDTKRTLLFTFNVPGSGNTYPKDMESLLPLMNMVIYSIDKAKKFRLNREGKQKADKNRARVEENFLKLTHVQRQEAAQSRREEKKRAEKERIMNEEDPEKQRRLEEAALRREQKKLEKKQMKMKQIKVKAM", "length": 483 }, "evidence": [ { "id": "F1NL71", "url": "https://omabrowser.org/oma/group/F1NL71/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VQR9-1", "protein_name": "PAT complex subunit CCDC47", "gene_name": "Dmel\\CG17593", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MRPVFAFLLLALICFASTKSESDFEEDDSDDFAEFDDGNFYAEPAAKNADSFSGGAGSSHGESRDDPPAKEPRKQAQNQESDEEDGLVEDDDEFEHFQDEEEFEGYDGGDSKDPPIDQKVEPKLNIPNIPLHFRTHWDSYWMEMLMVAGLLAYFANFFAGKAKNARLAQLWFSTHRALLDENFALVGDDGKAENENPGLIKESESLYTLWCSGRTCCEGMLVELKMIKRQDLVSLVAGLMRPQLDQAHIKIELTRGVMDAFVFAVGTKKTITKLFKEYTDLSKFCSLVGKPEDRYNVPTGFGVLSEIPEATSAILESRIITALNKYQSYIDYLHISDQFSGPIQQEEGGTLKQPETKAVLLAGFNLPKHAEMETIKPLLLLIFYLMERLKTYRMSKEGKAKSDKNRQRVEEEFLKSTHAARAEAAAQRREDKRKQEKERILADEDPEKQRRWEAKEQKRQAKRNAPKMKRLAVKSL", "length": 476 }, "evidence": [ { "id": "F1NL71", "url": "https://omabrowser.org/oma/group/F1NL71/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "F1NL71", "url": "https://www.uniprot.org/uniprotkb/F1NL71" } ], "pmid": "" }, { "name": "rough endoplasmic reticulum membrane", "id": "GO:0030867", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030867", "evidence": [ { "database": "UniProtKB", "id": "F1NL71", "url": "https://www.uniprot.org/uniprotkb/F1NL71" } ], "pmid": "" }, { "name": "multi-pass translocon complex", "id": "GO:0160064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160064", "evidence": [ { "database": "UniProtKB", "id": "F1NL71", "url": "https://www.uniprot.org/uniprotkb/F1NL71" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "F1NL71", "url": "https://www.uniprot.org/uniprotkb/F1NL71" } ], "pmid": "" }, { "name": "ribosome binding", "id": "GO:0043022", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043022", "evidence": [ { "database": "UniProtKB", "id": "F1NL71", "url": "https://www.uniprot.org/uniprotkb/F1NL71" } ], "pmid": "" }, { "name": "protein folding chaperone", "id": "GO:0044183", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044183", "evidence": [ { "database": "UniProtKB", "id": "F1NL71", "url": "https://www.uniprot.org/uniprotkb/F1NL71" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "ERAD pathway", "id": "GO:0036503", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036503", "evidence": [ { "database": "UniProtKB", "id": "F1NL71", "url": "https://www.uniprot.org/uniprotkb/F1NL71" } ], "pmid": "" }, { "name": "endoplasmic reticulum calcium ion homeostasis", "id": "GO:0032469", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032469", "evidence": [ { "database": "UniProtKB", "id": "F1NL71", "url": "https://www.uniprot.org/uniprotkb/F1NL71" } ], "pmid": "" }, { "name": "multi-pass transmembrane protein insertion into ER membrane", "id": "GO:0160063", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160063", "evidence": [ { "database": "UniProtKB", "id": "F1NL71", "url": "https://www.uniprot.org/uniprotkb/F1NL71" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 368, "end_pos": 370, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 368, "end_pos": 370 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1NN63-1", "uniprot_ac": "F1NN63", "uniprot_id": "F1NN63_CHICK", "mass": { "chemical_mass": 61549.0, "monoisotopic_mass": 61549.0 }, "refseq": { "ac": "NP_001033782", "name": "phosphoglucomutase-1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001033782" }, "gene_names": [ { "name": "PGM1", "type": "recommended", "evidence": [ { "id": "F1NN63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NN63" } ] }, { "name": "PGM1", "type": "synonym", "evidence": [ { "id": "NP_001033782", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001033782" } ] }, { "name": "phosphoglucomutase-1", "type": "synonym", "evidence": [ { "id": "NP_001033782", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001033782" } ] } ], "protein_names": [ { "name": "Phosphoglucomutase-1", "type": "recommended", "evidence": [ { "id": "F1NN63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NN63/entry#names_and_taxonomy" } ] }, { "name": "5.4.2.2", "type": "synonym", "evidence": [ { "id": "F1NN63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NN63/entry#names_and_taxonomy" } ] }, { "name": "Glucose phosphomutase 1", "type": "synonym", "evidence": [ { "id": "F1NN63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NN63/entry#names_and_taxonomy" } ] }, { "name": "phosphoglucomutase-1", "type": "synonym", "evidence": [ { "id": "NP_001033782", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001033782" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AF538281.1, HAEK01013191.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000239.1. On Mar 21, 2015 this sequence version replaced NP_001033782.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001033782", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001033782" } ] }, { "annotation": "Catalyzes the reversible isomerization of alpha-D-glucose 1-phosphate to alpha-D-glucose 6-phosphate. The mechanism proceeds via the intermediate compound alpha-D-glucose 1,6-bisphosphate. This enzyme participates in both the breakdown and synthesis of glucose.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZS16", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS16#function" }, { "database": "UniProtKB", "id": "ARBA00045679", "url": "https://www.uniprot.org/uniprotkb/ARBA00045679#function" }, { "database": "UniProtKB", "id": "A0A8V0ZX69", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZX69#function" }, { "database": "UniProtKB", "id": "A0A8V1A185", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A185#function" }, { "database": "UniProtKB", "id": "F1NN63", "url": "https://www.uniprot.org/uniprotkb/F1NN63#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NN63", "url": "https://www.uniprot.org/uniprotkb/F1NN63" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PGM1", "url": "https://www.uniprot.org/uniprotkb/F1NN63", "locus": { "chromosome": "8", "start_pos": 27570732, "end_pos": 27548353, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010024350", "url": "https://www.ensembl.org/id/ENSGALG00010024350" } ] } } ], "crossref": [ { "id": "F1NN63", "url": "https://alphafold.ebi.ac.uk/entry/F1NN63", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000011016", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000011016", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd03085", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03085", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "424691", "url": "https://www.ncbi.nlm.nih.gov/gene/424691", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR005841", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005841", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005844", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005844", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005845", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005845", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005846", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005846", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016055", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016055", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016066", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016066", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036900", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036900", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045244", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045244", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:424691", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424691", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WRDPLFG", "url": "https://omabrowser.org/oma/group/WRDPLFG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZS16", "url": "https://www.orthodb.org/?gene=A0A8V0ZS16", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZX69", "url": "https://www.orthodb.org/?gene=A0A8V0ZX69", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A185", "url": "https://www.orthodb.org/?gene=A0A8V1A185", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A4P2", "url": "https://www.orthodb.org/?gene=A0A8V1A4P2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NN63", "url": "https://www.orthodb.org/?gene=F1NN63", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22573", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22573", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22573:SF37", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22573:SF37", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22573:SF60", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22573:SF60", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02878", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02878", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02879", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02879", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02880", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02880", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24947", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24947", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-3322077", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3322077", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-6798695", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6798695", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-70221", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-70221", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-70370", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-70370", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001033782", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001033782", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "23536", "url": "https://www.rhea-db.org/rhea/23536", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "68748", "url": "https://www.rhea-db.org/rhea/68748", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "68752", "url": "https://www.rhea-db.org/rhea/68752", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0ZS16", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS16", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZS16-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS16-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZX69", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZX69", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZX69-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZX69-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A185", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A185", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A185-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A185-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A4P2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4P2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A4P2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4P2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NN63", "url": "https://www.uniprot.org/uniprotkb/F1NN63", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NN63-1", "url": "https://www.uniprot.org/uniprotkb/F1NN63-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVHIETVKTKAYADQKPGTSGLRKRVTVFQNNAHYAENFIQSILATVPPAERQEATLVVGGDGRFYMKDAIQIIVRIAAANGIGRLVIGQNGILSTPAVSCIIRKIKAIGGIILTASHNPGGPNGDFGIKFNTANGGPAPEGITDKIFQISKKIEEYAICPDLKVDLGTIGKQQFDLENKFKPFTVEIVDSVEAYANMLRNIFDFNALKELLSGKNHLKIRIDAMHGVVGPYVKKILCEELGAPANSAVNCTPLEDFGGHHPDPNLTYAADLVQTMKTGEYDFGAAFDGDGDRNMILGKHGFFVNPSDSVAVIAANIFSIPYFQQTGVRGFARSMPTSGALDRVAHATKIALYETPTGWKFFGNLMDANKLSLCGEESFGTGSDHIREKDGLWAVLAWLSILAARKQSVEDIMKDHWQKYGRNFFTRYDYEEVDADAAGKMMKDLETVMFDRSFVGKQLSAGDKVYTVEKADNFEYNDPVDGSVSRNQGLRLIFSDGSRIIFRLSGTGSAGATVRLYIDSYEKDAKKIHEDPQVMLAPLISIALKLSQLHERTGRTGPTVIT", "length": 562, "header": "tr|F1NN63-1|F1NN63_CHICK Isoform 1 of Phosphoglucomutase-1 OS=Gallus gallus OX=9031 GN=PGM1 PE=1 SV=2 CANONICAL=F1NN63-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZS16-1", "url": "https://www.uniprot.org/uniprotkb/F1NN63/entry#A0A8V0ZS16-1", "sequence": { "sequence": "MVHIETVKTKAYADQKPGTSGLRKRVTVFQNNAHYAENFIQSILATVPPAERQEATLVVGGDGRFYMKDAIQIIVRIAAANGIGRLVIGQNGILSTPAVSCIIRKIKAIGGIILTASHNPGGPNGDFGIKFNTANGGPAPEGITDKIFQISKKIEEYAICPDLKVDLGTIGKQQFDLENKFKPFTVEIVDSVEAYANMLRNIFDFNALKELLSGKNHLKIRIDAMHGVVGPYVKKILCEELGAPANSAVNCTPLEDFGGHHPDPNLTYAADLVQTMKTGEYDFGAAFDGDGDRNMILGKHGFFVNPSDSVAVIAANIFSIPYFQQTGVRGFARSMPTSGALDRVAHATKIALYETPTGWKFFGNLMDANKLSLCGEESFGTGSDHIREKDGLWAVLAWLSILAARKQSVEDIMKDHWQKYGRNFFTRYDYEEVDADAAGKMMKDLETVMFDRSFVGKQLSAGDKVYTVEKADNFEYNDPVDGSVSRNQGLRLIFSDGSRIIFRLSGTGSAGATVRLYIDSYEKDAKKIHEDPQAQSVGCCPEGAQSDPDVSPVVCIF", "length": 557, "header": "tr|A0A8V0ZS16-1|A0A8V0ZS16_CHICK Computationally mapped isoform of Phosphoglucomutase-1 OS=Gallus gallus OX=9031 GN=PGM1 PE=1 SV=1 CANONICAL=F1NN63-1" }, "locus": { "chromosome": "8", "start_pos": 27570397, "end_pos": 27548650, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010059404.1", "url": "https://www.ensembl.org/id/ENSGALT00010059404.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010036271.1", "url": "https://www.ensembl.org/id/ENSGALP00010036271.1" } ] } }, { "isoform_ac": "A0A8V0ZX69-1", "url": "https://www.uniprot.org/uniprotkb/F1NN63/entry#A0A8V0ZX69-1", "sequence": { "sequence": "MDGRRAVVCSRGRAACGHGQVWACSRELTFGWKLSQSRLLPCAPIVAEGISPYLRGKPGAFCGIQSSPADDRSIPSSAELIFQIGRLVIGQNGILSTPAVSCIIRKIKAIGGIILTASHNPGGPNGDFGIKFNTANGGPAPEGITDKIFQISKKIEEYAICPDLKVDLGTIGKQQFDLENKFKPFTVEIVDSVEAYANMLRNIFDFNALKELLSGKNHLKIRIDAMHGVVGPYVKKILCEELGAPANSAVNCTPLEDFGGHHPDPNLTYAADLVQTMKTGEYDFGAAFDGDGDRNMILGKHGFFVNPSDSVAVIAANIFSIPYFQQTGVRGFARSMPTSGALDRVAHATKIALYETPTGWKFFGNLMDANKLSLCGEESFGTGSDHIREKDGLWAVLAWLSILAARKQSVEDIMKDHWQKYGRNFFTRYDYEEVDADAAGKMMKDLETVMFDRSFVGKQLSAGDKVYTVEKADNFEYNDPVDGSVSRNQGLRLIFSDGSRIIFRLSGTGSAGATVRLYIDSYEKDAKKIHEDPQVMLAPLISIALKLSQLHERTGRTGPTVIT", "length": 563, "header": "tr|A0A8V0ZX69-1|A0A8V0ZX69_CHICK Computationally mapped isoform of Phosphoglucomutase-1 OS=Gallus gallus OX=9031 GN=PGM1 PE=1 SV=1 CANONICAL=F1NN63-1" }, "locus": { "chromosome": "8", "start_pos": 27566972, "end_pos": 27553321, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010059394.1", "url": "https://www.ensembl.org/id/ENSGALT00010059394.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010036263.1", "url": "https://www.ensembl.org/id/ENSGALP00010036263.1" } ] } }, { "isoform_ac": "A0A8V1A185-1", "url": "https://www.uniprot.org/uniprotkb/F1NN63/entry#A0A8V1A185-1", "sequence": { "sequence": "MVHIETVKTKAYADQKPGTSGLRKRVTVFQNNAHYAENFIQSILATVPPAERQEATLVVGGDGRFYMKDAIQIIVRIAAANGIGRLVIGQNGILSTPAVSCIIRKIKAIGGIILTASHNPGGPNGDFGIKFNTANGGPAPEGITDKIFQISKKIEEYAICPDLKVDLGTIGKQQFDLENKFKPFTVEIVDSVEAYANMLRNIFDFNALKELLSGKNHLKIRIDAMHGVVGPYVKKILCEELGAPANSAVNCTPLEDFGGHHPDPNLTYAADLVQTMKTGEYDFGAAFDGDGDRNMILGKHGFFVNPSDSVAVIAANIFSIPYFQQTGVRGFARSMPTSGALDRVAHATKIALYETPTGWKFFGNLMDANKLSLCGEESFGTGSDHIREKDGLWAVLAWLSILAARKQSVEDIMKDHWQKYGRNFFTRYDYEEVDADAAGKMMKDLETVMFDRSFVGKQLSAGDKVYTVEKADNFEYNDPVDGSVSRNQGLRLIFSDGSRIIFRLSGTGSAGATVRLYIDSYEKDAKKIHEDPQVMLAPLISIALKLSQLHERTGRTGPCYNIKARPGTKGKKPARRLFYCRVCRYKRNINFICVFKNTARYR", "length": 602, "header": "tr|A0A8V1A185-1|A0A8V1A185_CHICK Computationally mapped isoform of Phosphoglucomutase-1 OS=Gallus gallus OX=9031 GN=PGM1 PE=1 SV=1 CANONICAL=F1NN63-1" }, "locus": { "chromosome": "8", "start_pos": 27567094, "end_pos": 27548650, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010059395.1", "url": "https://www.ensembl.org/id/ENSGALT00010059395.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010036264.1", "url": "https://www.ensembl.org/id/ENSGALP00010036264.1" } ] } }, { "isoform_ac": "A0A8V1A4P2-1", "url": "https://www.uniprot.org/uniprotkb/F1NN63/entry#A0A8V1A4P2-1", "sequence": { "sequence": "MEAAPLPLLTVPTAPYSDQKPGTSGLRKKTYYFESKMNYLQNFIQSIFFSIDLRDRQGSSMVVGGDGRYLNKAAVELIVQMAAANGIGRLVIGQNGILSTPAVSCIIRKIKAIGGIILTASHNPGGPNGDFGIKFNTANGGPAPEGITDKIFQISKKIEEYAICPDLKVDLGTIGKQQFDLENKFKPFTVEIVDSVEAYANMLRNIFDFNALKELLSGKNHLKIRIDAMHGVVGPYVKKILCEELGAPANSAVNCTPLEDFGGHHPDPNLTYAADLVQTMKTGEYDFGAAFDGDGDRNMILGKHGFFVNPSDSVAVIAANIFSIPYFQQTGVRGFARSMPTSGALDRVAHATKIALYETPTGWKFFGNLMDANKLSLCGEESFGTGSDHIREKDGLWAVLAWLSILAARKQSVEDIMKDHWQKYGRNFFTRYDYEEVDADAAGKMMKDLETVMFDRSFVGKQLSAGDKVYTVEKADNFEYNDPVDGSVSRNQGLRLIFSDGSRIIFRLSGTGSAGATVRLYIDSYEKDAKKIHEDPQVMLAPLISIALKLSQLHERTGRTGPTVIT", "length": 566, "header": "tr|A0A8V1A4P2-1|A0A8V1A4P2_CHICK Computationally mapped isoform of Phosphoglucomutase 1 OS=Gallus gallus OX=9031 GN=PGM1 PE=1 SV=1 CANONICAL=F1NN63-1" }, "locus": { "chromosome": "8", "start_pos": 27566972, "end_pos": 27556308, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010059393.1", "url": "https://www.ensembl.org/id/ENSGALT00010059393.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010036262.1", "url": "https://www.ensembl.org/id/ENSGALP00010036262.1" } ] } }, { "isoform_ac": "F1NN63-1", "url": "https://www.uniprot.org/uniprotkb/F1NN63/entry#F1NN63-1", "sequence": { "sequence": "MVHIETVKTKAYADQKPGTSGLRKRVTVFQNNAHYAENFIQSILATVPPAERQEATLVVGGDGRFYMKDAIQIIVRIAAANGIGRLVIGQNGILSTPAVSCIIRKIKAIGGIILTASHNPGGPNGDFGIKFNTANGGPAPEGITDKIFQISKKIEEYAICPDLKVDLGTIGKQQFDLENKFKPFTVEIVDSVEAYANMLRNIFDFNALKELLSGKNHLKIRIDAMHGVVGPYVKKILCEELGAPANSAVNCTPLEDFGGHHPDPNLTYAADLVQTMKTGEYDFGAAFDGDGDRNMILGKHGFFVNPSDSVAVIAANIFSIPYFQQTGVRGFARSMPTSGALDRVAHATKIALYETPTGWKFFGNLMDANKLSLCGEESFGTGSDHIREKDGLWAVLAWLSILAARKQSVEDIMKDHWQKYGRNFFTRYDYEEVDADAAGKMMKDLETVMFDRSFVGKQLSAGDKVYTVEKADNFEYNDPVDGSVSRNQGLRLIFSDGSRIIFRLSGTGSAGATVRLYIDSYEKDAKKIHEDPQVMLAPLISIALKLSQLHERTGRTGPTVIT", "length": 562, "header": "tr|F1NN63-1|F1NN63_CHICK Isoform 1 of Phosphoglucomutase-1 OS=Gallus gallus OX=9031 GN=PGM1 PE=1 SV=2 CANONICAL=F1NN63-1" }, "locus": { "chromosome": "8", "start_pos": 27566972, "end_pos": 27548650, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010059401.1", "url": "https://www.ensembl.org/id/ENSGALT00010059401.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010036268.1", "url": "https://www.ensembl.org/id/ENSGALP00010036268.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "gga:424691", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424691", "resource": "KEGG Pathway" }, { "id": "R-GGA-3322077", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3322077", "resource": "Reactome", "description": "Glycogen synthesis" }, { "id": "R-GGA-6798695", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6798695", "resource": "Reactome", "description": "Neutrophil degranulation" }, { "id": "R-GGA-70221", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-70221", "resource": "Reactome", "description": "Glycogen breakdown (glycogenolysis)" }, { "id": "R-GGA-70370", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-70370", "resource": "Reactome", "description": "Galactose catabolism" } ], "orthologs": [ { "uniprot_canonical_ac": "O49299-1", "protein_name": "Probable phosphoglucomutase, cytoplasmic 1", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MVFKVSTVSTSPIDGQKPGTSGLRKKVKVFKQPNYLENFVQATFNALTAEKVKGATLVVSGDGRYYSKDAVQIIIKMAAANGVRRVWVGKNTLLSTPAVSAVIRERSGADGSKATGAFILTASHNPGGPTEDFGIKYNMENGGPAPESITDKIYENTKTIKEYPIAQDLPNVDISAVGVTSFEGPEGKFDVEVFDPADDYVKLMKSIFDFEAIRKLLSSPKFTFCYDALHGVAGAYAHRIFVEELGAQESALLNCTPKEDFGGGHPDPNLTYAKELVARMGLGKSDTGGEPPEFGAAADGDADRNMILGKRFFVTPSDSVAIIAANAIGAIPYFSSGLKGVARSMPTSAALDVVAKSLNLKFFEVPTGWKFFGNLMDAGMCSVCGEESFGTGSDHIREKDGIWAVLAWMSILAHKNKGNIDGNAKLVSVEDIVRQHWATYGRHYYTRYDYENVDAGKAKELMEHLVKLQSSIPEVNKIVKGIRSDVASVASADEFEYKDPVDGSISKHQGIRYLFEDGSRLVFRLSGTGSEGATIRLYIEQYEKDASKTGRESQEALSPLVDLALKLSKMEEFTGRSAPTVIT", "length": 583 }, "evidence": [ { "id": "F1NN63", "url": "https://omabrowser.org/oma/group/F1NN63/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "P36871-1", "protein_name": "Phosphoglucomutase-1", "gene_name": "PGM1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVKIVTVKTQAYQDQKPGTSGLRKRVKVFQSSANYAENFIQSIISTVEPAQRQEATLVVGGDGRFYMKEAIQLIARIAAANGIGRLVIGQNGILSTPAVSCIIRKIKAIGGIILTASHNPGGPNGDFGIKFNISNGGPAPEAITDKIFQISKTIEEYAVCPDLKVDLGVLGKQQFDLENKFKPFTVEIVDSVEAYATMLRSIFDFSALKELLSGPNRLKIRIDAMHGVVGPYVKKILCEELGAPANSAVNCVPLEDFGGHHPDPNLTYAADLVETMKSGEHDFGAAFDGDGDRNMILGKHGFFVNPSDSVAVIAANIFSIPYFQQTGVRGFARSMPTSGALDRVASATKIALYETPTGWKFFGNLMDASKLSLCGEESFGTGSDHIREKDGLWAVLAWLSILATRKQSVEDILKDHWQKYGRNFFTRYDYEEVEAEGANKMMKDLEALMFDRSFVGKQFSANDKVYTVEKADNFEYSDPVDGSISRNQGLRLIFTDGSRIVFRLSGTGSAGATIRLYIDSYEKDVAKINQDPQVMLAPLISIALKVSQLQERTGRTAPTVIT", "length": 562 }, "evidence": [ { "id": "F1NN63", "url": "https://omabrowser.org/oma/group/F1NN63/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q08DP0-1", "protein_name": "Phosphoglucomutase-1", "gene_name": "PGM1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MVKIVTVKTKAYQDQKPGTSGLRKRVKVFQSSSNYAENFIQSIISTVEPAQRQEATLVVGGDGRFYMKEAIQLIVRIAAANGIGRLVIGQNGILSTPAVSCIIRKIKAIGGIILTASHNPGGPNGDFGIKFNISNGGPAPEAITDKIFQISKTIEEYAICPDLHVDLGVLGKQQFDLENKFKPFTVEIVDSVEAYATMLRNIFDFNALKELLSGPNRLKIRIDAMHGVVGPYVKKILCEELGAPANSAVNCVPLEDFGGHHPDPNLTYAADLVETMKTGEHDFGAAFDGDGDRNMILGKHGFFVNPSDSVAVIAANIFSIPYFQQTGVRGFARSMPTSGALDRVANATKIALYETPTGWKFFGNLMDASKLSLCGEESFGTGSDHIREKDGLWAVLAWLSILATRKQSVEDILKDHWQKYGRNFFTRYDYEEVEAEGANKMMKELEALISDRSFVGKQFPVGDKVYTVEKIDNFEYSDPVDGSISRNQGLRLLFADGSRIIFRLSGTGSAGATIRLYIDSYEKDLAKIYQDPQVMLAPLISIALKVSQLQEKTGRTAPTVIT", "length": 562 }, "evidence": [ { "id": "F1NN63", "url": "https://omabrowser.org/oma/group/F1NN63/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "magnesium ion binding", "id": "GO:0000287", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000287", "evidence": [ { "database": "UniProtKB", "id": "F1NN63", "url": "https://www.uniprot.org/uniprotkb/F1NN63" } ], "pmid": "" }, { "name": "phosphoglucomutase activity", "id": "GO:0004614", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004614", "evidence": [ { "database": "UniProtKB", "id": "F1NN63", "url": "https://www.uniprot.org/uniprotkb/F1NN63" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1NN63", "url": "https://www.uniprot.org/uniprotkb/F1NN63" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F1NN63", "url": "https://www.uniprot.org/uniprotkb/F1NN63" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "glucose metabolic process", "id": "GO:0006006", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006006", "evidence": [ { "database": "UniProtKB", "id": "F1NN63", "url": "https://www.uniprot.org/uniprotkb/F1NN63" } ], "pmid": "" }, { "name": "carbohydrate metabolic process", "id": "GO:0005975", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005975", "evidence": [ { "database": "UniProtKB", "id": "F1NN63", "url": "https://www.uniprot.org/uniprotkb/F1NN63" } ], "pmid": "" }, { "name": "galactose catabolic process via UDP-galactose, Leloir pathway", "id": "GO:0033499", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033499", "evidence": [ { "database": "UniProtKB", "id": "F1NN63", "url": "https://www.uniprot.org/uniprotkb/F1NN63" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 250, "end_pos": 252, "annotation": "n_glycosylation_sequon" }, { "start_pos": 265, "end_pos": 267, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "23536", "name": "", "equation": "alpha-D-glucose 1-phosphate = alpha-D-glucose 6-phosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1NN63-1" ], "evidence": [ { "id": "23536", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/23536" } ] }, { "id": "68748", "name": "", "equation": "O-phospho-L-seryl-[protein] + alpha-D-glucose 1-phosphate = alpha-D-glucose 1,6-bisphosphate + L-seryl-[protein]", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1NN63-1" ], "evidence": [ { "id": "68748", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/68748" } ] }, { "id": "68752", "name": "", "equation": "alpha-D-glucose 1,6-bisphosphate + L-seryl-[protein] = O-phospho-L-seryl-[protein] + alpha-D-glucose 6-phosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1NN63-1" ], "evidence": [ { "id": "68752", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/68752" } ] }, { "id": "R-GGA-6798745", "name": "Exocytosis of tertiary granule lumen proteins", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "extracellular region, tertiary granule lumen", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0X7U8-1", "A0A8V0X868-1", "A0A8V0XIL3-1", "A0A8V1AIR0-1", "A2JDL7-1", "P08267-1", "A0A1D5PN36-1", "Q90629-1", "R4GH41-1", "A0A8V0Y6Q3-1", "A0A8V1AMW1-1", "A0A8V0ZN26-1", "A0A8V0ZPK4-1", "F1NN63-1", "A0A8V0YXL9-1", "A0A8V0ZNL2-1", "E1C9D9-1", "A0A8V0ZG12-1", "A0A3Q2UCN1-1", "P00698-1", "Q05744-1", "A0A8V0XX04-1", "A0A8V0Y248-1" ], "evidence": [ { "id": "R-GGA-6798745", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6798745" } ] }, { "id": "R-GGA-6800434", "name": "Exocytosis of ficolin-rich granule lumen proteins", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "extracellular region, ficolin-1-rich granule lumen", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A1D5PAA8-1", "A0A8V0X7U8-1", "A0A1D5PLH7-1", "A0A8V0XGV3-1", "A0A8V1AAF2-1", "A0A8V1ADZ5-1", "A0A8V1AIR0-1", "F1NI04-1", "A0A1D5PSE5-1", "A0A8V0XAS9-1", "O57535-1", "P08267-1", "Q90835-1", "A0A1L1RSD2-1", "R4GH41-1", "A0A8V0Y6Q3-1", "A0A8V1AMW1-1", "A0A8V0ZPK4-1", "A0A8V0ZQ64-1", "A0A8V0ZR27-1", "A0A8V0ZWJ4-1", "F1NN63-1", "A0A8V1A3K8-1", "A0A8V1A4Q4-1", "A0A8V0YHC8-1", "A0A8V0YXL9-1", "A0A8V0ZFP5-1", "A0A8V0ZG96-1", "A0A8V0ZTG8-1", "A0A8V0ZVL2-1", "A0A8V0Z0N7-1", "A0A8V0Z0Z6-1", "A0A8V0Z3A2-1", "F1NG97-1", "A0A8V0ZAK2-1", "A0A8V0ZG12-1", "A0A1D5PIQ5-1", "Q05744-1", "A0A8V0XX04-1", "A0A8V0XXA9-1", "A0A8V0YAA4-1", "A0A8V0Y4H1-1", "A0A8V0Y5M6-1", "A0A8V0YDR9-1", "A0A8V0YHT7-1" ], "evidence": [ { "id": "R-GGA-6800434", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6800434" } ] }, { "id": "R-GGA-9638125", "name": "PGM1:Mg2+ isomerises G1P to G6P", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1NN63-1" ], "evidence": [ { "id": "R-GGA-9638125", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9638125" } ] }, { "id": "R-GGA-9638127", "name": "PGM1:Mg2+ isomerises G6P to G1P", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1NN63-1" ], "evidence": [ { "id": "R-GGA-9638127", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9638127" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A1D5PAA8", "gene_name": "GYG1", "activity": [ { "ec_number": "2.4.1.186", "activity": "[1,4-alpha-D-glucosyl](n)-L-tyrosyl-[glycogenin] + UDP-alpha-D-glucose = [1,4-alpha-D-glucosyl](n+1)-L-tyrosyl-[glycogenin] + UDP + H(+).", "evidence": [ { "id": "A0A1D5PAA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PAA8" } ] }, { "ec_number": "2.4.1.186", "activity": "", "evidence": [ { "id": "A0A1D5PAA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PAA8" } ] } ] }, { "uniprot_ac": "A0A1D5PIQ5", "gene_name": "MAPK14", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PIQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PIQ5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A1D5PIQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PIQ5" } ] } ] }, { "uniprot_ac": "A0A1D5PLH7", "gene_name": "PRDX4", "activity": [ { "ec_number": "1.11.1.24", "activity": "a hydroperoxide + [thioredoxin]-dithiol = an alcohol + [thioredoxin]-disulfide + H2O.", "evidence": [ { "id": "A0A1D5PLH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLH7" } ] }, { "ec_number": "1.11.1.24", "activity": "", "evidence": [ { "id": "A0A1D5PLH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLH7" } ] } ] }, { "uniprot_ac": "A0A1D5PN36", "gene_name": "LOC107054567", "activity": [ { "ec_number": "3.4.21.4", "activity": "Preferential cleavage: Arg-|-Xaa, Lys-|-Xaa.", "evidence": [ { "id": "A0A1D5PN36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PN36" } ] }, { "ec_number": "3.4.21.4", "activity": "", "evidence": [ { "id": "A0A1D5PN36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PN36" } ] } ] }, { "uniprot_ac": "A0A1D5PSE5", "gene_name": "ACLY", "activity": [ { "ec_number": "2.3.3.8", "activity": "oxaloacetate + acetyl-CoA + ADP + phosphate = citrate + ATP + CoA.", "evidence": [ { "id": "A0A1D5PSE5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PSE5" } ] }, { "ec_number": "2.3.3.8", "activity": "", "evidence": [ { "id": "A0A1D5PSE5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PSE5" } ] } ] }, { "uniprot_ac": "A0A1L1RSD2", "gene_name": "GUSB", "activity": [ { "ec_number": "3.2.1.31", "activity": "a beta-D-glucuronoside + H2O = D-glucuronate + an alcohol.", "evidence": [ { "id": "A0A1L1RSD2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RSD2" } ] }, { "ec_number": "3.2.1.31", "activity": "", "evidence": [ { "id": "A0A1L1RSD2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RSD2" } ] } ] }, { "uniprot_ac": "A0A3Q2UCN1", "gene_name": "PTPN6", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3Q2UCN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UCN1" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A3Q2UCN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UCN1" } ] } ] }, { "uniprot_ac": "A0A8V0X7U8", "gene_name": "ALDOA", "activity": [ { "ec_number": "4.1.2.13", "activity": "beta-D-fructose 1,6-bisphosphate = D-glyceraldehyde 3-phosphate + dihydroxyacetone phosphate.", "evidence": [ { "id": "A0A8V0X7U8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X7U8" } ] }, { "ec_number": "4.1.2.13", "activity": "", "evidence": [ { "id": "A0A8V0X7U8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X7U8" } ] } ] }, { "uniprot_ac": "A0A8V0X868", "gene_name": "GGH", "activity": [ { "ec_number": "3.4.19.9", "activity": "(6S)-5,6,7,8-tetrahydrofolyl-(gamma-L-Glu)(n) + (n-1) H2O = (6S)-5,6,7,8-tetrahydrofolate + (n-1) L-glutamate.", "evidence": [ { "id": "A0A8V0X868", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X868" } ] }, { "ec_number": "3.4.19.9", "activity": "", "evidence": [ { "id": "A0A8V0X868", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X868" } ] } ] }, { "uniprot_ac": "A0A8V0XAS9", "gene_name": "CAPN1", "activity": [ { "ec_number": "3.4.22.52", "activity": "Broad endopeptidase specificity.", "evidence": [ { "id": "A0A8V0XAS9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XAS9" } ] }, { "ec_number": "3.4.22.52", "activity": "", "evidence": [ { "id": "A0A8V0XAS9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XAS9" } ] } ] }, { "uniprot_ac": "A0A8V0XGV3", "gene_name": "DDX3X", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XGV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XGV3" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0XGV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XGV3" } ] } ] }, { "uniprot_ac": "A0A8V0XIL3", "gene_name": "NIT2", "activity": [ { "ec_number": "3.5.1.3", "activity": "2-oxosuccinamate + H2O = oxaloacetate + NH4(+).", "evidence": [ { "id": "A0A8V0XIL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XIL3" } ] }, { "ec_number": "3.5.1.3", "activity": "", "evidence": [ { "id": "A0A8V0XIL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XIL3" } ] } ] }, { "uniprot_ac": "A0A8V0XX04", "gene_name": "QPCT", "activity": [ { "ec_number": "2.3.2.5", "activity": "N-terminal L-glutaminyl-[peptide] = N-terminal 5-oxo-L-prolyl-[peptide] + NH4(+).", "evidence": [ { "id": "A0A8V0XX04", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XX04" } ] }, { "ec_number": "2.3.2.5", "activity": "", "evidence": [ { "id": "A0A8V0XX04", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XX04" } ] } ] }, { "uniprot_ac": "A0A8V0XXA9", "gene_name": "GPI", "activity": [ { "ec_number": "5.3.1.9", "activity": "alpha-D-fructose 6-phosphate = beta-D-fructose 6-phosphate.", "evidence": [ { "id": "A0A8V0XXA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XXA9" } ] }, { "ec_number": "5.3.1.9", "activity": "", "evidence": [ { "id": "A0A8V0XXA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XXA9" } ] } ] }, { "uniprot_ac": "A0A8V0Y248", "gene_name": "QSOX1", "activity": [ { "ec_number": "1.8.3.2", "activity": "2 R'C(R)SH + O2 = R'C(R)S-S(R)CR' + H2O2.", "evidence": [ { "id": "A0A8V0Y248", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y248" } ] }, { "ec_number": "1.8.3.2", "activity": "", "evidence": [ { "id": "A0A8V0Y248", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y248" } ] } ] }, { "uniprot_ac": "A0A8V0Y4H1", "gene_name": "CTSB", "activity": [ { "ec_number": "3.4.22.1", "activity": "Hydrolysis of proteins with broad specificity for peptide bonds. Preferentially cleaves -Arg-Arg-|-Xaa bonds in small molecule substrates (thus differing from cathepsin L). In addition to being an endopeptidase, shows peptidyl-dipeptidase activity, liberating C-terminal dipeptides.", "evidence": [ { "id": "A0A8V0Y4H1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y4H1" } ] }, { "ec_number": "3.4.22.1", "activity": "", "evidence": [ { "id": "A0A8V0Y4H1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y4H1" } ] } ] }, { "uniprot_ac": "A0A8V0Y5M6", "gene_name": "HK3", "activity": [ { "ec_number": "2.7.1.1", "activity": "D-fructose + ATP = D-fructose 6-phosphate + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y5M6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5M6" } ] }, { "ec_number": "2.7.1.1", "activity": "", "evidence": [ { "id": "A0A8V0Y5M6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5M6" } ] } ] }, { "uniprot_ac": "A0A8V0Y6Q3", "gene_name": "LTA4H", "activity": [ { "ec_number": "3.3.2.6", "activity": "leukotriene A4 + H2O = leukotriene B4.", "evidence": [ { "id": "A0A8V0Y6Q3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y6Q3" } ] }, { "ec_number": "3.3.2.6", "activity": "", "evidence": [ { "id": "A0A8V0Y6Q3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y6Q3" } ] } ] }, { "uniprot_ac": "A0A8V0YAA4", "gene_name": "XRCC6", "activity": [ { "ec_number": "4.2.99.18", "activity": "2'-deoxyribonucleotide-(2'-deoxyribose 5'-phosphate)-2'-deoxyribonucleotide-DNA = a 3'-end 2'-deoxyribonucleotide-(2,3-dehydro-2,3-deoxyribose 5'-phosphate)-DNA + a 5'-end 5'-phospho-2'-deoxyribonucleoside-DNA + H(+).", "evidence": [ { "id": "A0A8V0YAA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAA4" } ] }, { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YAA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAA4" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "A0A8V0YAA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAA4" } ] }, { "ec_number": "4.2.99.18", "activity": "", "evidence": [ { "id": "A0A8V0YAA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAA4" } ] } ] }, { "uniprot_ac": "A0A8V0YDR9", "gene_name": "KCMF1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YDR9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDR9" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0YDR9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDR9" } ] } ] }, { "uniprot_ac": "A0A8V0YHC8", "gene_name": "VCP", "activity": [ { "ec_number": "3.6.4.6", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YHC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHC8" } ] }, { "ec_number": "3.6.4.6", "activity": "", "evidence": [ { "id": "A0A8V0YHC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHC8" } ] } ] }, { "uniprot_ac": "A0A8V0YHT7", "gene_name": "DERA", "activity": [ { "ec_number": "4.1.2.4", "activity": "2-deoxy-D-ribose 5-phosphate = D-glyceraldehyde 3-phosphate + acetaldehyde.", "evidence": [ { "id": "A0A8V0YHT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHT7" } ] }, { "ec_number": "4.1.2.4", "activity": "", "evidence": [ { "id": "A0A8V0YHT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHT7" } ] } ] }, { "uniprot_ac": "A0A8V0YXL9", "gene_name": "MMP9", "activity": [ { "ec_number": "3.4.24.35", "activity": "Cleavage of gelatin types I and V and collagen types IV and V.", "evidence": [ { "id": "A0A8V0YXL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXL9" } ] }, { "ec_number": "3.4.24.35", "activity": "", "evidence": [ { "id": "A0A8V0YXL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXL9" } ] } ] }, { "uniprot_ac": "A0A8V0Z0N7", "gene_name": "PPIA", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "A0A8V0Z0N7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z0N7" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "A0A8V0Z0N7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z0N7" } ] } ] }, { "uniprot_ac": "A0A8V0Z0Z6", "gene_name": "GLB1", "activity": [ { "ec_number": "3.2.1.23", "activity": "Hydrolysis of terminal non-reducing beta-D-galactose residues in beta-D-galactosides.", "evidence": [ { "id": "A0A8V0Z0Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z0Z6" } ] }, { "ec_number": "3.2.1.23", "activity": "", "evidence": [ { "id": "A0A8V0Z0Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z0Z6" } ] } ] }, { "uniprot_ac": "A0A8V0Z3A2", "gene_name": "PPIE", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "A0A8V0Z3A2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3A2" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "A0A8V0Z3A2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3A2" } ] } ] }, { "uniprot_ac": "A0A8V0ZAK2", "gene_name": "PYGL", "activity": [ { "ec_number": "2.4.1.1", "activity": "[(1->4)-alpha-D-glucosyl](n) + phosphate = [(1->4)-alpha-D-glucosyl](n-1) + alpha-D-glucose 1-phosphate.", "evidence": [ { "id": "A0A8V0ZAK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAK2" } ] }, { "ec_number": "2.4.1.1", "activity": "", "evidence": [ { "id": "A0A8V0ZAK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAK2" } ] } ] }, { "uniprot_ac": "A0A8V0ZFP5", "gene_name": "PGAM1", "activity": [ { "ec_number": "5.4.2.11", "activity": "(2R)-2-phosphoglycerate = (2R)-3-phosphoglycerate.", "evidence": [ { "id": "A0A8V0ZFP5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFP5" } ] }, { "ec_number": "5.4.2.4", "activity": "(2R)-3-phospho-glyceroyl phosphate = (2R)-2,3-bisphosphoglycerate + H(+).", "evidence": [ { "id": "A0A8V0ZFP5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFP5" } ] }, { "ec_number": "5.4.2.4", "activity": "", "evidence": [ { "id": "A0A8V0ZFP5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFP5" } ] }, { "ec_number": "5.4.2.11", "activity": "", "evidence": [ { "id": "A0A8V0ZFP5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFP5" } ] } ] }, { "uniprot_ac": "A0A8V0ZG12", "gene_name": "CDA", "activity": [ { "ec_number": "3.5.4.5", "activity": "cytidine + H2O + H(+) = uridine + NH4(+).", "evidence": [ { "id": "A0A8V0ZG12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG12" } ] }, { "ec_number": "3.5.4.5", "activity": "", "evidence": [ { "id": "A0A8V0ZG12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG12" } ] } ] }, { "uniprot_ac": "A0A8V0ZG96", "gene_name": "PKLR", "activity": [ { "ec_number": "2.7.1.40", "activity": "ITP + pyruvate = IDP + phosphoenolpyruvate + H(+).", "evidence": [ { "id": "A0A8V0ZG96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG96" } ] }, { "ec_number": "2.7.1.40", "activity": "", "evidence": [ { "id": "A0A8V0ZG96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG96" } ] } ] }, { "uniprot_ac": "A0A8V0ZN26", "gene_name": "LOC121106429", "activity": [ { "ec_number": "3.4.21.4", "activity": "Preferential cleavage: Arg-|-Xaa, Lys-|-Xaa.", "evidence": [ { "id": "A0A8V0ZN26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN26" } ] }, { "ec_number": "3.4.21.4", "activity": "", "evidence": [ { "id": "A0A8V0ZN26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN26" } ] } ] }, { "uniprot_ac": "A0A8V0ZNL2", "gene_name": "C1R", "activity": [ { "ec_number": "3.4.21.41", "activity": "Selective cleavage of Lys(or Arg)-|-Ile bond in complement subcomponent C1s to form the active form of C1s (EC 3.4.21.42).", "evidence": [ { "id": "A0A8V0ZNL2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNL2" } ] }, { "ec_number": "3.4.21.41", "activity": "", "evidence": [ { "id": "A0A8V0ZNL2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNL2" } ] } ] }, { "uniprot_ac": "A0A8V0ZPK4", "gene_name": "IDH1", "activity": [ { "ec_number": "1.1.1.42", "activity": "D-threo-isocitrate + NADP(+) = 2-oxoglutarate + CO2 + NADPH.", "evidence": [ { "id": "A0A8V0ZPK4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPK4" } ] }, { "ec_number": "1.1.1.42", "activity": "", "evidence": [ { "id": "A0A8V0ZPK4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPK4" } ] } ] }, { "uniprot_ac": "A0A8V0ZQ64", "gene_name": "AGL", "activity": [ { "ec_number": "2.4.1.25", "activity": "Transfers a segment of a (1->4)-alpha-D-glucan to a new position in an acceptor, which may be glucose or a (1->4)-alpha-D-glucan.", "evidence": [ { "id": "A0A8V0ZQ64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ64" } ] }, { "ec_number": "3.2.1.33", "activity": "Hydrolysis of (1->6)-alpha-D-glucosidic branch linkages in glycogen phosphorylase limit dextrin.", "evidence": [ { "id": "A0A8V0ZQ64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ64" } ] }, { "ec_number": "2.4.1.25", "activity": "", "evidence": [ { "id": "A0A8V0ZQ64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ64" } ] }, { "ec_number": "3.2.1.33", "activity": "", "evidence": [ { "id": "A0A8V0ZQ64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ64" } ] } ] }, { "uniprot_ac": "A0A8V0ZR27", "gene_name": "PAFAH1B2", "activity": [ { "ec_number": "3.1.1.47", "activity": "a 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine + H2O = a 1-O-alkyl-sn-glycero-3-phosphocholine + acetate + H(+).", "evidence": [ { "id": "A0A8V0ZR27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR27" } ] }, { "ec_number": "3.1.1.47", "activity": "", "evidence": [ { "id": "A0A8V0ZR27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR27" } ] } ] }, { "uniprot_ac": "A0A8V0ZTG8", "gene_name": "PFKL", "activity": [ { "ec_number": "2.7.1.11", "activity": "beta-D-fructose 6-phosphate + ATP = beta-D-fructose 1,6-bisphosphate + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZTG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTG8" } ] }, { "ec_number": "2.7.1.11", "activity": "", "evidence": [ { "id": "A0A8V0ZTG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTG8" } ] } ] }, { "uniprot_ac": "A0A8V0ZVL2", "gene_name": "CAT", "activity": [ { "ec_number": "1.11.1.6", "activity": "2 H2O2 = O2 + 2 H2O.", "evidence": [ { "id": "A0A8V0ZVL2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVL2" } ] }, { "ec_number": "1.11.1.6", "activity": "", "evidence": [ { "id": "A0A8V0ZVL2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVL2" } ] } ] }, { "uniprot_ac": "A0A8V0ZWJ4", "gene_name": "ALOX5", "activity": [ { "ec_number": "1.13.11.34", "activity": "(5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 = leukotriene A4 + H2O.", "evidence": [ { "id": "A0A8V0ZWJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWJ4" } ] }, { "ec_number": "1.13.11.34", "activity": "", "evidence": [ { "id": "A0A8V0ZWJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWJ4" } ] } ] }, { "uniprot_ac": "A0A8V1A3K8", "gene_name": "APEH", "activity": [ { "ec_number": "3.4.19.1", "activity": "Internal cleavage of oxidized and glycated proteins.", "evidence": [ { "id": "A0A8V1A3K8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3K8" } ] }, { "ec_number": "3.4.19.1", "activity": "", "evidence": [ { "id": "A0A8V1A3K8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3K8" } ] } ] }, { "uniprot_ac": "A0A8V1A4Q4", "gene_name": "MAPK3", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4Q4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4Q4" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V1A4Q4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4Q4" } ] } ] }, { "uniprot_ac": "A0A8V1AAF2", "gene_name": "MIF", "activity": [ { "ec_number": "5.3.2.1", "activity": "3-phenylpyruvate = enol-phenylpyruvate.", "evidence": [ { "id": "A0A8V1AAF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAF2" } ] }, { "ec_number": "5.3.3.12", "activity": "L-dopachrome = 5,6-dihydroxyindole-2-carboxylate.", "evidence": [ { "id": "A0A8V1AAF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAF2" } ] }, { "ec_number": "5.3.3.12", "activity": "", "evidence": [ { "id": "A0A8V1AAF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAF2" } ] }, { "ec_number": "5.3.2.1", "activity": "", "evidence": [ { "id": "A0A8V1AAF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAF2" } ] } ] }, { "uniprot_ac": "A0A8V1ADZ5", "gene_name": "HDHD3", "activity": [ { "ec_number": "4.2.1.24", "activity": "2 5-aminolevulinate = porphobilinogen + 2 H2O + H(+).", "evidence": [ { "id": "A0A8V1ADZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADZ5" } ] }, { "ec_number": "4.2.1.24", "activity": "", "evidence": [ { "id": "A0A8V1ADZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADZ5" } ] } ] }, { "uniprot_ac": "A0A8V1AIR0", "gene_name": "ALDOC", "activity": [ { "ec_number": "4.1.2.13", "activity": "beta-D-fructose 1,6-bisphosphate = D-glyceraldehyde 3-phosphate + dihydroxyacetone phosphate.", "evidence": [ { "id": "A0A8V1AIR0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIR0" } ] }, { "ec_number": "4.1.2.13", "activity": "", "evidence": [ { "id": "A0A8V1AIR0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIR0" } ] } ] }, { "uniprot_ac": "A0A8V1AMW1", "gene_name": "CANT1", "activity": [ { "ec_number": "3.6.1.6", "activity": "a ribonucleoside 5'-diphosphate + H2O = a ribonucleoside 5'-phosphate + phosphate + H(+).", "evidence": [ { "id": "A0A8V1AMW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMW1" } ] }, { "ec_number": "3.6.1.6", "activity": "", "evidence": [ { "id": "A0A8V1AMW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMW1" } ] } ] }, { "uniprot_ac": "A2JDL7", "gene_name": "LOC121107389", "activity": [ { "ec_number": "3.4.21.4", "activity": "Preferential cleavage: Arg-|-Xaa, Lys-|-Xaa.", "evidence": [ { "id": "A2JDL7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2JDL7" } ] }, { "ec_number": "3.4.21.4", "activity": "", "evidence": [ { "id": "A2JDL7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2JDL7" } ] } ] }, { "uniprot_ac": "E1C9D9", "gene_name": "MMP1", "activity": [ { "ec_number": "3.4.24.7", "activity": "Cleavage of the triple helix of collagen at about three-quarters of the length of the molecule from the N-terminus, at 775-Gly-|-Ile-776 in the alpha1(I) chain. Cleaves synthetic substrates and alpha-macroglobulins at bonds where P1' is a hydrophobic residue.", "evidence": [ { "id": "E1C9D9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C9D9" } ] }, { "ec_number": "3.4.24.7", "activity": "", "evidence": [ { "id": "E1C9D9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C9D9" } ] } ] }, { "uniprot_ac": "F1NG97", "gene_name": "AMPD3", "activity": [ { "ec_number": "3.5.4.6", "activity": "AMP + H2O + H(+) = IMP + NH4(+).", "evidence": [ { "id": "F1NG97", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NG97" } ] }, { "ec_number": "3.5.4.6", "activity": "", "evidence": [ { "id": "F1NG97", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NG97" } ] } ] }, { "uniprot_ac": "F1NI04", "gene_name": "GNS", "activity": [ { "ec_number": "3.1.6.14", "activity": "Hydrolysis of the 6-sulfate groups of the N-acetyl-D-glucosamine 6-sulfate units of heparan sulfate and keratan sulfate.", "evidence": [ { "id": "F1NI04", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NI04" } ] }, { "ec_number": "3.1.6.14", "activity": "", "evidence": [ { "id": "F1NI04", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NI04" } ] } ] }, { "uniprot_ac": "F1NN63", "gene_name": "PGM1", "activity": [ { "ec_number": "5.4.2.2", "activity": "alpha-D-glucose 1-phosphate = alpha-D-glucose 6-phosphate.", "evidence": [ { "id": "F1NN63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NN63" } ] }, { "ec_number": "5.4.2.2", "activity": "", "evidence": [ { "id": "F1NN63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NN63" } ] } ] }, { "uniprot_ac": "O57535", "gene_name": "", "activity": [ { "ec_number": "2.7.4.6", "activity": "UDP + ATP = UTP + ADP.", "evidence": [ { "id": "O57535", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O57535" } ] }, { "ec_number": "2.7.4.6", "activity": "", "evidence": [ { "id": "O57535", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O57535" } ] } ] }, { "uniprot_ac": "P00698", "gene_name": "LYZ", "activity": [ { "ec_number": "3.2.1.17", "activity": "Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins.", "evidence": [ { "id": "P00698", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00698" } ] }, { "ec_number": "3.2.1.17", "activity": "", "evidence": [ { "id": "P00698", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00698" } ] } ] }, { "uniprot_ac": "P08267", "gene_name": "FTH", "activity": [ { "ec_number": "1.16.3.1", "activity": "4 Fe(2+) + O2 + 4 H(+) = 4 Fe(3+) + 2 H2O.", "evidence": [ { "id": "P08267", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P08267" } ] }, { "ec_number": "1.16.3.1", "activity": "", "evidence": [ { "id": "P08267", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P08267" } ] } ] }, { "uniprot_ac": "Q05744", "gene_name": "CTSD", "activity": [ { "ec_number": "3.4.23.5", "activity": "Specificity similar to, but narrower than, that of pepsin A. Does not cleave the 4-Gln-|-His-5 bond in B chain of insulin.", "evidence": [ { "id": "Q05744", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q05744" } ] }, { "ec_number": "3.4.23.5", "activity": "", "evidence": [ { "id": "Q05744", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q05744" } ] } ] }, { "uniprot_ac": "Q90629", "gene_name": "", "activity": [ { "ec_number": "3.4.21.4", "activity": "Preferential cleavage: Arg-|-Xaa, Lys-|-Xaa.", "evidence": [ { "id": "Q90629", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q90629" } ] }, { "ec_number": "3.4.21.4", "activity": "", "evidence": [ { "id": "Q90629", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q90629" } ] } ] }, { "uniprot_ac": "Q90835", "gene_name": "EEF1A", "activity": [ { "ec_number": "3.6.5.-", "activity": "", "evidence": [ { "id": "Q90835", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q90835" } ] } ] }, { "uniprot_ac": "R4GH41", "gene_name": "ASAH1", "activity": [ { "ec_number": "3.5.1.23", "activity": "an N-acylsphing-4-enine + H2O = sphing-4-enine + a fatty acid.", "evidence": [ { "id": "R4GH41", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GH41" } ] }, { "ec_number": "3.5.1.23", "activity": "", "evidence": [ { "id": "R4GH41", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GH41" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1NN63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NN63" }, { "id": "PF02878", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02878" }, { "id": "PF02879", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02879" }, { "id": "PF02880", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02880" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Alpha-D-phosphohexomutase alpha/beta/alpha", "eco_id": "ECO_0000259", "start_pos": 15, "end_pos": 157, "start_aa": "Gln", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "5.4.2.2", "ec_name": "alpha-D-glucose 1-phosphate = alpha-D-glucose 6-phosphate.", "evidence": [ { "id": "5.4.2.2", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:5.4.2.2" }, { "id": "5.4.2.2", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=5.4.2.2" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 250, "end_pos": 252 }, { "start_pos": 265, "end_pos": 267 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1NV32-1", "uniprot_ac": "F1NV32", "uniprot_id": "F1NV32_CHICK", "mass": { "chemical_mass": 36969.0, "monoisotopic_mass": 36969.0 }, "refseq": { "ac": "XP_015134526", "name": "secretory carrier-associated membrane protein 2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015134526" }, "gene_names": [ { "name": "SCAMP2", "type": "recommended", "evidence": [ { "id": "F1NV32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NV32" } ] }, { "name": "SCAMP2", "type": "synonym", "evidence": [ { "id": "XP_015134526", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015134526" } ] } ], "protein_names": [ { "name": "Secretory carrier-associated membrane protein", "type": "recommended", "evidence": [ { "id": "F1NV32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NV32/entry#names_and_taxonomy" } ] }, { "name": "Secretory carrier membrane protein", "type": "synonym", "evidence": [ { "id": "F1NV32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NV32/entry#names_and_taxonomy" } ] }, { "name": "secretory carrier-associated membrane protein 2", "type": "synonym", "evidence": [ { "id": "XP_015134526", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015134526" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052541.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015134526", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015134526" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NV32", "url": "https://www.uniprot.org/uniprotkb/F1NV32" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SCAMP2", "url": "https://www.uniprot.org/uniprotkb/F1NV32", "locus": { "chromosome": "10", "start_pos": 2439119, "end_pos": 2430101, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010023476", "url": "https://www.ensembl.org/id/ENSGALG00010023476" } ] } } ], "crossref": [ { "id": "F1NV32", "url": "https://alphafold.ebi.ac.uk/entry/F1NV32", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000001689", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000001689", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "769853", "url": "https://www.ncbi.nlm.nih.gov/gene/769853", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR007273", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007273", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:769853", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:769853", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CLAWFTG", "url": "https://omabrowser.org/oma/group/CLAWFTG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZV95", "url": "https://www.orthodb.org/?gene=A0A8V0ZV95", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NV32", "url": "https://www.orthodb.org/?gene=F1NV32", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10687", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10687", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10687:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10687:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04144", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04144", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015134526", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015134526", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZV95", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZV95", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZV95-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZV95-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NV32", "url": "https://www.uniprot.org/uniprotkb/F1NV32", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NV32-1", "url": "https://www.uniprot.org/uniprotkb/F1NV32-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSSFDTNPFADPVDVNPFQDPSVTQLTNASQSGLDEFNPFSESSQLTHAARTAPATQPSGPSQPAVLQTSVEPTPQAVAAAAQAGLLQQQAELERKAAELEKKERELQNNAASINPRQNNWPPLPRKCPIKPCFYQDFSADIPADYQRICKMLYYLWMLHSVTLLLNLLACLAWFMVHAEKGVDFGLSILWFVLFTPCAFLCWYRPIYKAFRSDSSFSFFVFFFVFFCQIAIYIIQAVGIPGWGDSGWIAALSELHRNTAVAIIMMVVAGFFTLCAVLSLFLLKQVHSLYRRTGASFQRAQEEFSQGILTNRSFQNAAAGAASSAARSAFRGN", "length": 333, "header": "tr|F1NV32-1|F1NV32_CHICK Isoform 1 of Secretory carrier-associated membrane protein OS=Gallus gallus OX=9031 GN=SCAMP2 PE=1 SV=3 CANONICAL=F1NV32-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZV95-1", "url": "https://www.uniprot.org/uniprotkb/F1NV32/entry#A0A8V0ZV95-1", "sequence": { "sequence": "MSSFDTNPFADPVDVNPFQDPSVTQLTNASQSGLDEFNPFSESSQLTHAARTAPATQPSGPSQPAVLQTSVEPTPQAVAAAAQAGLLQQQAELERKAAELEKKERELQNNAASINPRQNNWPPLPRKCPIKPCFYQDFSADIPADYQRICKMLYYLWMLHSVTLLLNLLACLAWFMVHAEKGVDFGLSILWFVLFTPCAFLCWYRPIYKAFRSDSSFSFFVFFFVFFCQIAIYIIQAVGIPGWGDSGWIAALSELHRNTAVAIIMMVVAGFFTLCAVLSLFLLKQVSGLELLAESLWLGCTHVGLPPLVCRAGDQPFPEDGVRALPKWCWRCCLCQC", "length": 337, "header": "tr|A0A8V0ZV95-1|A0A8V0ZV95_CHICK Computationally mapped isoform of Secretory carrier-associated membrane protein OS=Gallus gallus OX=9031 GN=SCAMP2 PE=1 SV=1 CANONICAL=F1NV32-1" }, "locus": { "chromosome": "10", "start_pos": 2438214, "end_pos": 2430204, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010057187.1", "url": "https://www.ensembl.org/id/ENSGALT00010057187.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034780.1", "url": "https://www.ensembl.org/id/ENSGALP00010034780.1" } ] } }, { "isoform_ac": "F1NV32-1", "url": "https://www.uniprot.org/uniprotkb/F1NV32/entry#F1NV32-1", "sequence": { "sequence": "MSSFDTNPFADPVDVNPFQDPSVTQLTNASQSGLDEFNPFSESSQLTHAARTAPATQPSGPSQPAVLQTSVEPTPQAVAAAAQAGLLQQQAELERKAAELEKKERELQNNAASINPRQNNWPPLPRKCPIKPCFYQDFSADIPADYQRICKMLYYLWMLHSVTLLLNLLACLAWFMVHAEKGVDFGLSILWFVLFTPCAFLCWYRPIYKAFRSDSSFSFFVFFFVFFCQIAIYIIQAVGIPGWGDSGWIAALSELHRNTAVAIIMMVVAGFFTLCAVLSLFLLKQVHSLYRRTGASFQRAQEEFSQGILTNRSFQNAAAGAASSAARSAFRGN", "length": 333, "header": "tr|F1NV32-1|F1NV32_CHICK Isoform 1 of Secretory carrier-associated membrane protein OS=Gallus gallus OX=9031 GN=SCAMP2 PE=1 SV=3 CANONICAL=F1NV32-1" }, "locus": { "chromosome": "10", "start_pos": 2438600, "end_pos": 2430204, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010057183.1", "url": "https://www.ensembl.org/id/ENSGALT00010057183.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034777.1", "url": "https://www.ensembl.org/id/ENSGALP00010034777.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 74, "start_aa": "Thr", "end_pos": 74, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr74", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:769853", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:769853", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A5G2R660-1", "protein_name": "Secretory carrier-associated membrane protein", "gene_name": "SCAMP2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSAFDTNPFADPVDVNPFQDPSVTQLTNAPQGGLAEFNPFSETNAATTVPVTQLPGPSQPAVLQPSVEPTQPTPQLLLRQASRFLPTRFLAVSELSERQMLLGGDSILRDSYMRELPKAVASAAQASLLRQQEELDRKAAELERKERELQNTVANLHVRENNWPPLPIWCPIKPCFYQDFSTEIPADYQRICKMLYYLWMLHSVTLFLNLLACLAWFLVDTSRGVDFGLSILWFVIFTPCAFLCWYRPIYKAFRSDNSFSFFVFFFVFFCQIGIYIIQLVGIPSLGDSGWIAALSTLKEDLAVSIIMMVVAGFFTLCAVLSLFLLKRVHSLYRRTGASFQQAQEEFSQGIFSSRTFQSAASSAARGAFQGN", "length": 371 }, "evidence": [ { "id": "F1NV32", "url": "https://omabrowser.org/oma/group/F1NV32/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "O15127-1", "protein_name": "Secretory carrier-associated membrane protein 2", "gene_name": "SCAMP2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSAFDTNPFADPVDVNPFQDPSVTQLTNAPQGGLAEFNPFSETNAATTVPVTQLPGSSQPAVLQPSVEPTQPTPQAVVSAAQAGLLRQQEELDRKAAELERKERELQNTVANLHVRQNNWPPLPSWCPVKPCFYQDFSTEIPADYQRICKMLYYLWMLHSVTLFLNLLACLAWFSGNSSKGVDFGLSILWFLIFTPCAFLCWYRPIYKAFRSDNSFSFFVFFFVFFCQIGIYIIQLVGIPGLGDSGWIAALSTLDNHSLAISVIMMVVAGFFTLCAVLSVFLLQRVHSLYRRTGASFQQAQEEFSQGIFSSRTFHRAASSAAQGAFQGN", "length": 329 }, "evidence": [ { "id": "F1NV32", "url": "https://omabrowser.org/oma/group/F1NV32/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9ERN0-1", "protein_name": "Secretory carrier-associated membrane protein 2", "gene_name": "Scamp2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAFDTNPFADPVDVNPFQDPSVTQLTNAPQSGLAEFNPFSETNAATTVPATQAPGPSQPAVLQPSVEPAQPTPQAVAAAAQAGLLRQQEELDRKAAELERKERELQNTAANLHVRDNNWPPLPSWCPVKPCFYQDFSTEIPADYQRICKMLYYLWMLHSVTLFLNLLACLAWFTSDAANGTAFGLSILWFLIFTPCAFLCWYRPIYKAFRSDNSFSFFVFFFVFFCQIGIYFIQLIGLPNLGTSGWLAALSTMKNGPLAVTIIMMVVAGFFTLCAGLSLFLLQRVHAFYRRTGASFQQAQEEFSQGIFSSRTFRGAASSAARGAFQGN", "length": 329 }, "evidence": [ { "id": "F1NV32", "url": "https://omabrowser.org/oma/group/F1NV32/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9SXA5-1", "protein_name": "Secretory carrier-associated membrane protein 5", "gene_name": "SCAMP5", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MGGRYDRNTFDEQDEVNPFANPGSVPAASNSRLSPLPPEPAGFGYGRTVDIPLDRPGSGAQDLKKKEKELQAKEADLRRREQDLKRKQDAAARAGIVIEAKNWPTFFPLIHHDIANEILVRLQRLQYIAFATYLGLVLALFWNIIAVTTAWIKGEGVTIWLLAVIYFISGVPGGYVLWYRPLYRAFRSDSAFNFGWFFLFYMLHILFCLFAAVAPPIVFKGKSLAGILPAIDVLSAQALVGIFYFIGFGLFCLESVVSIWVIQQVYMYFRGSGKADDMRRDAARGAMRAAI", "length": 291 }, "evidence": [ { "id": "F1NV32", "url": "https://omabrowser.org/oma/group/F1NV32/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "F1NV32", "url": "https://www.uniprot.org/uniprotkb/F1NV32" } ], "pmid": "" }, { "name": "exocytosis", "id": "GO:0006887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006887", "evidence": [ { "database": "UniProtKB", "id": "F1NV32", "url": "https://www.uniprot.org/uniprotkb/F1NV32" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "trans-Golgi network membrane", "id": "GO:0032588", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032588", "evidence": [ { "database": "UniProtKB", "id": "F1NV32", "url": "https://www.uniprot.org/uniprotkb/F1NV32" } ], "pmid": "" }, { "name": "recycling endosome membrane", "id": "GO:0055038", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055038", "evidence": [ { "database": "UniProtKB", "id": "F1NV32", "url": "https://www.uniprot.org/uniprotkb/F1NV32" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "F1NV32", "url": "https://www.uniprot.org/uniprotkb/F1NV32" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 28, "end_pos": 30, "annotation": "n_glycosylation_sequon" }, { "start_pos": 311, "end_pos": 313, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 74 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 28, "end_pos": 30 }, { "start_pos": 311, "end_pos": 313 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1NZW9-1", "uniprot_ac": "F1NZW9", "uniprot_id": "F1NZW9_CHICK", "mass": { "chemical_mass": 36079.0, "monoisotopic_mass": 36079.0 }, "refseq": { "ac": "NP_001026445", "name": "UDP-N-acetylglucosamine transporter", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026445" }, "gene_names": [ { "name": "SLC35A3", "type": "recommended", "evidence": [ { "id": "F1NZW9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NZW9" } ] }, { "name": "SLC35A2", "type": "synonym", "evidence": [ { "id": "NP_001026445", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026445" } ] }, { "name": "SLC35A3", "type": "synonym", "evidence": [ { "id": "NP_001026445", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026445" } ] } ], "protein_names": [ { "name": "Solute carrier family 35 member A3", "type": "synonym", "evidence": [ { "id": "F1NZW9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NZW9/entry#names_and_taxonomy" } ] }, { "name": "UDP-N-acetylglucosamine transporter", "type": "synonym", "evidence": [ { "id": "NP_001026445", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026445" } ] }, { "name": "solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3", "type": "synonym", "evidence": [ { "id": "NP_001026445", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026445" } ] }, { "name": "solute carrier family 35 member A2", "type": "synonym", "evidence": [ { "id": "NP_001026445", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026445" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ720360.1, SRR13267655.133663.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA103992290, SAMEA103992323 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000239.1. On Sep 23, 2021 this sequence version replaced NP_001026445.2.", "evidence": [ { "database": "RefSeq", "id": "NP_001026445", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026445" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NZW9", "url": "https://www.uniprot.org/uniprotkb/F1NZW9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SLC35A3", "url": "https://www.uniprot.org/uniprotkb/F1NZW9", "locus": { "chromosome": "8", "start_pos": 11701615, "end_pos": 11722979, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010023953", "url": "https://www.ensembl.org/id/ENSGALG00010023953" } ] } } ], "crossref": [ { "id": "F1NZW9", "url": "https://alphafold.ebi.ac.uk/entry/F1NZW9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000005340", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000005340", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "424472", "url": "https://www.ncbi.nlm.nih.gov/gene/424472", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR007271", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007271", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037185", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037185", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:424472", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424472", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "AIMYVIQ", "url": "https://omabrowser.org/oma/group/AIMYVIQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZX33", "url": "https://www.orthodb.org/?gene=A0A8V0ZX33", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZYQ0", "url": "https://www.orthodb.org/?gene=A0A8V0ZYQ0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A2H8", "url": "https://www.orthodb.org/?gene=A0A8V1A2H8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A2I6", "url": "https://www.orthodb.org/?gene=A0A8V1A2I6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NZW9", "url": "https://www.orthodb.org/?gene=F1NZW9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10231", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10231", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04142", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04142", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-727802", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-727802", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001026445", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026445", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZX33", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZX33", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZX33-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZX33-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZYQ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZYQ0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZYQ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZYQ0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A2H8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2H8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A2H8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2H8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A2I6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2I6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A2I6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2I6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NZW9", "url": "https://www.uniprot.org/uniprotkb/F1NZW9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NZW9-1", "url": "https://www.uniprot.org/uniprotkb/F1NZW9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSTNLKYLSLGILVFQTTSLVLTMRYSRTLKEEGPRYLSSTAVVLAELLKILSCVLLVYKDSKCNLRTLNRVLHDEILNKPMETLKLAIPSGIYTLQNNLLYVALSNLDAATYQVTYQLKILTTALFSVSMLSKKLGIYQWLSLVILMTGVAFVQWPSDSQATAAKEHSAGSQFVGLMAVLIACFSSGFAGVYFEKILKETKQSVWIRNIQLGFFGSIFGLMGVYIYDGEQLSKDGFFQGYNKLTWIVVVLQALGGLVIAAVIKYADNILKGFATSLSIILSTLISYFWLQDFVPTSVFFFGAILVIAATFLYGYDPKPAGNPTKA", "length": 326, "header": "tr|F1NZW9-1|F1NZW9_CHICK Isoform 1 of Solute carrier family 35 member A3 OS=Gallus gallus OX=9031 GN=SLC35A3 PE=1 SV=3 CANONICAL=F1NZW9-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZX33-1", "url": "https://www.uniprot.org/uniprotkb/F1NZW9/entry#A0A8V0ZX33-1", "sequence": { "sequence": "MCNKLKRKRKSKEENNQEMSTNLKYLSLGILVFQTTSLVLTMRYSRTLKEEGPRYLSSTAVVLAELLKILSCVLLVYKDSKCNLRTLNRVLHDEILNKPMETLKLAIPSGIYTLQNNLLYVALSNLDAATYQVTYQLKILTTALFSVSMLSKKLGIYQWLSLVILMTGVAFVQWPSDSQATAAKEHSAGSQFVGLMAVLIACFSSGFAGVYFEKILKETKQSVWIRNIQLGFFGSIFGLMGVYIYDGEQLSKDGFFQGYNKLTWIVVVLQALGGLVIAAVIKYADNILKGFATSLSIILSTLISYFWLQDFVPTSVFFFGAILVIAATFLYGYDPKPAGNPTKA", "length": 344, "header": "tr|A0A8V0ZX33-1|A0A8V0ZX33_CHICK Computationally mapped isoform of Solute carrier family 35 member A3 OS=Gallus gallus OX=9031 GN=SLC35A3 PE=1 SV=1 CANONICAL=F1NZW9-1" }, "locus": { "chromosome": "8", "start_pos": 11718401, "end_pos": 11705628, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010058337.1", "url": "https://www.ensembl.org/id/ENSGALT00010058337.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010035446.1", "url": "https://www.ensembl.org/id/ENSGALP00010035446.1" } ] } }, { "isoform_ac": "A0A8V0ZYQ0-1", "url": "https://www.uniprot.org/uniprotkb/F1NZW9/entry#A0A8V0ZYQ0-1", "sequence": { "sequence": "MRADKEENNQEMSTNLKYLSLGILVFQTTSLVLTMRYSRTLKEEGPRYLSSTAVVLAELLKILSCVLLVYKDSKCNLRTLNRVLHDEILNKPMETLKLAIPSGIYTLQNNLLYVALSNLDAATYQVTYQLKILTTALFSVSMLSKKLGIYQWLSLVILMTGVAFVQWPSDSQATAAKEHSAGSQFVGLMAVLIACFSSGFAGVYFEKILKETKQSVWIRNIQLGFFGSIFGLMGVYIYDGEQLSKDGFFQGYNKLTWIVVVLQALGGLVIAAVIKYADNILKGFATSLSIILSTLISYFWLQDFVPTSVFFFGAILVIAATFLYGYDPKPAGNPTKA", "length": 337, "header": "tr|A0A8V0ZYQ0-1|A0A8V0ZYQ0_CHICK Computationally mapped isoform of Solute carrier family 35 member A3 OS=Gallus gallus OX=9031 GN=SLC35A3 PE=1 SV=1 CANONICAL=F1NZW9-1" }, "locus": { "chromosome": "8", "start_pos": 11715921, "end_pos": 11705628, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010058341.1", "url": "https://www.ensembl.org/id/ENSGALT00010058341.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010035450.1", "url": "https://www.ensembl.org/id/ENSGALP00010035450.1" } ] } }, { "isoform_ac": "A0A8V1A2H8-1", "url": "https://www.uniprot.org/uniprotkb/F1NZW9/entry#A0A8V1A2H8-1", "sequence": { "sequence": "MVLLWEKFLYFFFVMIADQENTIAQGDDVEENNQEMSTNLKYLSLGILVFQTTSLVLTMRYSRTLKEEGPRYLSSTAVVLAELLKILSCVLLVYKDSKCNLRTLNRVLHDEILNKPMETLKLAIPSGIYTLQNNLLYVALSNLDAATYQVTYQLKILTTALFSVSMLSKKLGIYQWLSLVILMTGVAFVQWPSDSQATAAKEHSAGSQFVGLMAVLIACFSSGFAGVYFEKILKETKQSVWIRNIQLGFFGSIFGLMGVYIYDGEQLSKDGFFQGYNKLTWIVVVLQALGGLVIAAVIKYADNILKGFATSLSIILSTLISYFWLQDFVPTSVFFFGAILVIAATFLYGYDPKPAGNPTKA", "length": 361, "header": "tr|A0A8V1A2H8-1|A0A8V1A2H8_CHICK Computationally mapped isoform of Solute carrier family 35 member A3 OS=Gallus gallus OX=9031 GN=SLC35A3 PE=1 SV=1 CANONICAL=F1NZW9-1" }, "locus": { "chromosome": "8", "start_pos": 11715543, "end_pos": 11705628, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010058334.1", "url": "https://www.ensembl.org/id/ENSGALT00010058334.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010035443.1", "url": "https://www.ensembl.org/id/ENSGALP00010035443.1" } ] } }, { "isoform_ac": "A0A8V1A2I6-1", "url": "https://www.uniprot.org/uniprotkb/F1NZW9/entry#A0A8V1A2I6-1", "sequence": { "sequence": "MSTNLKYLSLGILVFQTTSLVLTMRYSRTLKEEGPRYLSSTAVVLAELLKILSCVLLVYKDSKCNLRTLNRVLHDEILNKPMETLKLAIPSGIYTLQNNLLYVALSNLDAATYQWPSDSQATAAKEHSAGSQFVGLMAVLIACFSSGFAGVYFEKILKETKQSVWIRNIQLGFFGSIFGLMGVYIYDGEQLSKDGFFQGYNKLTWIVVVLQALGGLVIAAVIKYADNILKGFATSLSIILSTLISYFWLQDFVPTSVFFFGAILVIAATFLYGYDPKPAGNPTKA", "length": 285, "header": "tr|A0A8V1A2I6-1|A0A8V1A2I6_CHICK Computationally mapped isoform of Solute carrier family 35 member A3 OS=Gallus gallus OX=9031 GN=SLC35A3 PE=1 SV=1 CANONICAL=F1NZW9-1" }, "locus": { "chromosome": "8", "start_pos": 11713004, "end_pos": 11705628, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010058344.1", "url": "https://www.ensembl.org/id/ENSGALT00010058344.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010035453.1", "url": "https://www.ensembl.org/id/ENSGALP00010035453.1" } ] } }, { "isoform_ac": "F1NZW9-1", "url": "https://www.uniprot.org/uniprotkb/F1NZW9/entry#F1NZW9-1", "sequence": { "sequence": "MSTNLKYLSLGILVFQTTSLVLTMRYSRTLKEEGPRYLSSTAVVLAELLKILSCVLLVYKDSKCNLRTLNRVLHDEILNKPMETLKLAIPSGIYTLQNNLLYVALSNLDAATYQVTYQLKILTTALFSVSMLSKKLGIYQWLSLVILMTGVAFVQWPSDSQATAAKEHSAGSQFVGLMAVLIACFSSGFAGVYFEKILKETKQSVWIRNIQLGFFGSIFGLMGVYIYDGEQLSKDGFFQGYNKLTWIVVVLQALGGLVIAAVIKYADNILKGFATSLSIILSTLISYFWLQDFVPTSVFFFGAILVIAATFLYGYDPKPAGNPTKA", "length": 326, "header": "tr|F1NZW9-1|F1NZW9_CHICK Isoform 1 of Solute carrier family 35 member A3 OS=Gallus gallus OX=9031 GN=SLC35A3 PE=1 SV=3 CANONICAL=F1NZW9-1" }, "locus": { "chromosome": "8", "start_pos": 11713004, "end_pos": 11705628, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010058347.1", "url": "https://www.ensembl.org/id/ENSGALT00010058347.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010035456.1", "url": "https://www.ensembl.org/id/ENSGALP00010035456.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:424472", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424472", "resource": "KEGG Pathway" }, { "id": "R-GGA-727802", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-727802", "resource": "Reactome", "description": "Transport of nucleotide sugars" } ], "orthologs": [ { "uniprot_canonical_ac": "Q6AXR5-1", "protein_name": "UDP-N-acetylglucosamine transporter", "gene_name": "Slc35a3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSANLKYLSLGILVFQTTSLVLTMRYSRTLKEEGPRYLSSTAVVVAEFLKIMACIFLVYKDSKCSVRTLNRVLHDEILNKPMETLKLAIPSGIYTLQNNLLYVALSNLDAATYQVTYQLKILTTALFSVSMLGKKLGMYQWLSLVILMAGVAFVQWPSDSQELNSKDLSTGSQFVGLMAVLIACFSSGFAGVYFEKILKETKQSVWIRNIQLGFFGSIFGLMGVYVYDGELVSKNGFFQGYNQLTWIVVVLQALGGLVIAAVIKYADNILKGFATSLSIILSTIISYFWLQDFVPTSVFFLGAILVIAATFLYGYDPKPAGNPTKA", "length": 326 }, "evidence": [ { "id": "F1NZW9", "url": "https://omabrowser.org/oma/group/F1NZW9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6YC49-1", "protein_name": "UDP-N-acetylglucosamine transporter", "gene_name": "SLC35A3", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSANLKYLSLGILVFQTTSLVLTMRYSRTLKEEGPRYLSSTAVVVAELLKIMACILLVYKDSKCSLRALNRILHDEILNKPMETLKLAIPSGIYTLQNNLLYVALSNLDAATYQVTYQLKILTTALFSVSMLSKKLGVYQWLSLVILMTGVAFVQWPSDSQELNSKELSAGSQFVGLMAVLTACFSSGFAGVYFEKILKETKQSVWIRNIQLGFFGSIFGLMGVYVYDGELVSKNGFFQGYNRLTWIVVVLQALGGLVIAAVIKYADNILKGFATSLSIILSTLISYFWLQDFVPTSVFFLGAILVITATFLYGYDPKPAGNPTKA", "length": 326 }, "evidence": [ { "id": "F1NZW9", "url": "https://omabrowser.org/oma/group/F1NZW9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q8R1T4-1", "protein_name": "UDP-N-acetylglucosamine transporter", "gene_name": "Slc35a3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSANLKYLSLGILVFQTTSLVLTMRYSRTLKEEGPRYLSSTAVVVAEFLKIMACIFLVYKDSKCSVRALNRVLHDEILNKPMETLKLAIPSGIYTLQNNLLYVALSNLDAATYQVTYQLKILTTALFSVSMLGKKLGVYQWLSLVILMAGVAFVQWPSDSQELNSKDLSTGSQFVGLMAVLTACFSSGFAGVYFEKILKETKQSVWIRNIQLGFFGSIFGLMGVYVYDGELVSKNGFFQGYNQLTWIVVALQALGGLVIAAVIKYADNILKGFATSLSIILSTIISYFWLQDFVPTSVFFLGAILVIAATFLYGYDPKPAGNPTKA", "length": 326 }, "evidence": [ { "id": "F1NZW9", "url": "https://omabrowser.org/oma/group/F1NZW9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9Y2D2-1", "protein_name": "UDP-N-acetylglucosamine transporter", "gene_name": "SLC35A3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MFANLKYVSLGILVFQTTSLVLTMRYSRTLKEEGPRYLSSTAVVVAELLKIMACILLVYKDSKCSLRALNRVLHDEILNKPMETLKLAIPSGIYTLQNNLLYVALSNLDAATYQVTYQLKILTTALFSVSMLSKKLGVYQWLSLVILMTGVAFVQWPSDSQLDSKELSAGSQFVGLMAVLTACFSSGFAGVYFEKILKETKQSVWIRNIQLGFFGSIFGLMGVYIYDGELVSKNGFFQGYNRLTWIVVVLQALGGLVIAAVIKYADNILKGFATSLSIILSTLISYFWLQDFVPTSVFFLGAILVITATFLYGYDPKPAGNPTKA", "length": 325 }, "evidence": [ { "id": "F1NZW9", "url": "https://omabrowser.org/oma/group/F1NZW9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "F1NZW9", "url": "https://www.uniprot.org/uniprotkb/F1NZW9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "pyrimidine nucleotide-sugar transmembrane transporter activity", "id": "GO:0015165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015165", "evidence": [ { "database": "UniProtKB", "id": "F1NZW9", "url": "https://www.uniprot.org/uniprotkb/F1NZW9" } ], "pmid": "" }, { "name": "UDP-galactose transmembrane transporter activity", "id": "GO:0005459", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005459", "evidence": [ { "database": "UniProtKB", "id": "F1NZW9", "url": "https://www.uniprot.org/uniprotkb/F1NZW9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "transmembrane transport", "id": "GO:0055085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055085", "evidence": [ { "database": "UniProtKB", "id": "F1NZW9", "url": "https://www.uniprot.org/uniprotkb/F1NZW9" } ], "pmid": "" }, { "name": "UDP-N-acetylglucosamine transmembrane transport", "id": "GO:1990569", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990569", "evidence": [ { "database": "UniProtKB", "id": "F1NZW9", "url": "https://www.uniprot.org/uniprotkb/F1NZW9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1NQJ6-1", "uniprot_ac": "F1NQJ6", "uniprot_id": "F1NQJ6_CHICK", "mass": { "chemical_mass": 59063.0, "monoisotopic_mass": 59063.0 }, "refseq": { "ac": "XP_413755", "name": "ubiquitin carboxyl-terminal hydrolase 3 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_413755" }, "gene_names": [ { "name": "USP3", "type": "recommended", "evidence": [ { "id": "F1NQJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NQJ6" } ] }, { "name": "USP3", "type": "synonym", "evidence": [ { "id": "XP_413755", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_413755" } ] } ], "protein_names": [ { "name": "Ubiquitin carboxyl-terminal hydrolase", "type": "recommended", "evidence": [ { "id": "F1NQJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NQJ6/entry#names_and_taxonomy" } ] }, { "name": "3.4.19.12", "type": "synonym", "evidence": [ { "id": "F1NQJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NQJ6/entry#names_and_taxonomy" } ] }, { "name": "ubiquitin carboxyl-terminal hydrolase 3 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_413755", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_413755" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052541.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Dec 16, 2011 this sequence version replaced XP_413755.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_413755", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_413755" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NQJ6", "url": "https://www.uniprot.org/uniprotkb/F1NQJ6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "USP3", "url": "https://www.uniprot.org/uniprotkb/F1NQJ6", "locus": { "chromosome": "10", "start_pos": 4061581, "end_pos": 4095870, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010024482", "url": "https://www.ensembl.org/id/ENSGALG00010024482" } ] } } ], "crossref": [ { "id": "F1NQJ6", "url": "https://alphafold.ebi.ac.uk/entry/F1NQJ6", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000003427", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000003427", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd02674", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02674", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "415369", "url": "https://www.ncbi.nlm.nih.gov/gene/415369", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001394", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001394", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001607", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001607", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018200", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018200", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028889", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028889", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038765", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038765", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050185", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050185", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "KYWVKYL", "url": "https://omabrowser.org/oma/group/KYWVKYL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZZY1", "url": "https://www.orthodb.org/?gene=A0A8V0ZZY1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZZZ1", "url": "https://www.orthodb.org/?gene=A0A8V0ZZZ1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A1U7", "url": "https://www.orthodb.org/?gene=A0A8V1A1U7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A5A7", "url": "https://www.orthodb.org/?gene=A0A8V1A5A7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NQJ6", "url": "https://www.orthodb.org/?gene=F1NQJ6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21646", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21646", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21646:SF19", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21646:SF19", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00443", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00443", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02148", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02148", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-5689880", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5689880", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_413755", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_413755", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZZY1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZY1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZZY1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZY1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZZZ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZZ1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZZZ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZZ1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A1U7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1U7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A1U7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1U7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A5A7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5A7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A5A7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5A7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NQJ6", "url": "https://www.uniprot.org/uniprotkb/F1NQJ6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NQJ6-1", "url": "https://www.uniprot.org/uniprotkb/F1NQJ6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MECPHLGSSVCIAPDSAKFPQGSPSSWCCSVCRSNKSPWVCLTCSSVHCGRYVNGHAKKHYEDAQIPMTNHKKTEKQEKVQHTVCMDCSSYSTYCYRCDDFVVNDTKLGLVQKVREHLQNLENSAFTSDRHRKRKLLENSSLNSKLLKVNGSTTALCATGLRNLGNTCFMNAILQSLSNIQQFCCYFKELPAVELRNGKTAGRRTYHTRSQGDNNVSLVEEFRKTLCALWQGSQTAFSPESLFYVVWKIMPNFRGYQQQDAHEFMRYLLDHLHLELQGGFNGVSRSVILQENSSLTASSKCCINGASTVVTAIFGGILQNEVNCLICGTESRKFDPFLDLSLDIPSQFRNKRTKNQENGPMCTLRDCLRSFTDLEELDETELYMCHKCKKKQKSTKKFWIQKLPKVLCLHLKRFHWTAYLRNKVDTYVEFPLRGLDMKCYLLEPENSGPESCLYDLAAVVVHHGSGVGSGHYTAYAAHEGRWFHFNDSTVTLTDEETVVKAKAYILFYVERQAKSGSDKL", "length": 520, "header": "tr|F1NQJ6-1|F1NQJ6_CHICK Isoform 1 of Ubiquitin carboxyl-terminal hydrolase OS=Gallus gallus OX=9031 GN=USP3 PE=3 SV=4 CANONICAL=F1NQJ6-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZZY1-1", "url": "https://www.uniprot.org/uniprotkb/F1NQJ6/entry#A0A8V0ZZY1-1", "sequence": { "sequence": "MSYTACFVLGWEGAFCQAAGLLLSGPQEKHHKSTVCRSNKSPWVCLTCSSVHCGRYVNGHAKKHYEDAQIPMTNHKKTEKQEKVQHTVCMDCSSYSTYCYRCDDFVVNDTKLGLVQKVREHLQNLENSAFTSDRHRKRKLLENSSLNSKLLKVNGSTTALCATGLRNLGNTCFMNAILQSLSNIQQFCCYFKELPAVELRNGKTAGRRTYHTRSQGDNNVSLVEEFRKTLCALWQGSQTAFSPESLFYVVWKIMPNFRGYQQQDAHEFMRYLLDHLHLELQGGFNGVSRSVILQENSSLTASSKCCINGASTVVTAIFGGILQNEVNCLICGTESRKFDPFLDLSLDIPSQFRNKRTKNQENGPMCTLRDCLRSFTDLEELDETELYMCHKCKKKQKSTKKFWIQKLPKVLCLHLKRFHWTAYLRNKVDTYVEFPLRGLDMKCYLLEPENSGPESCLYDLAAVVVHHGSGVGSGHYTAYAAHEGRWFHFNDSTVTLTDEETVVKAKAYILFYVERQAKSGSDKL", "length": 524, "header": "tr|A0A8V0ZZY1-1|A0A8V0ZZY1_CHICK Computationally mapped isoform of Ubiquitin carboxyl-terminal hydrolase OS=Gallus gallus OX=9031 GN=USP3 PE=3 SV=1 CANONICAL=F1NQJ6-1" }, "locus": { "chromosome": "10", "start_pos": 4091500, "end_pos": 4062321, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010059713.1", "url": "https://www.ensembl.org/id/ENSGALT00010059713.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010036478.1", "url": "https://www.ensembl.org/id/ENSGALP00010036478.1" } ] } }, { "isoform_ac": "A0A8V0ZZZ1-1", "url": "https://www.uniprot.org/uniprotkb/F1NQJ6/entry#A0A8V0ZZZ1-1", "sequence": { "sequence": "MECPHLGSSVCIAPDSAKFPQGSPSSWCCSGDYRCDDFVVNDTKLGLVQKVREHLQNLENSAFTSDRHRKRKLLENSSLNSKLLKVNGSTTALCATGLRNLGNTCFMNAILQSLSNIQQFCCYFKELPAVELRNGKTAGRRTYHTRSQGDNNVSLVEEFRKTLCALWQGSQTAFSPESLFYVVWKIMPNFRGYQQQDAHEFMRYLLDHLHLELQGGFNGVSRSVILQENSSLTASSKCCINGASTVVTAIFGGILQNEVNCLICGTESRKFDPFLDLSLDIPSQFRNKRTKNQENGPMCTLRDCLRSFTDLEELDETELYMCHKCKKKQKSTKKFWIQKLPKVLCLHLKRFHWTAYLRNKVDTYVEFPLRGLDMKCYLLEPENSGPESCLYDLAAVVVHHGSGVGSGHYTAYAAHEGRWFHFNDSTVTLTDEETVVKAKAYILFYVERQAKSGSDKL", "length": 457, "header": "tr|A0A8V0ZZZ1-1|A0A8V0ZZZ1_CHICK Computationally mapped isoform of Ubiquitin carboxyl-terminal hydrolase OS=Gallus gallus OX=9031 GN=USP3 PE=3 SV=1 CANONICAL=F1NQJ6-1" }, "locus": { "chromosome": "10", "start_pos": 4095716, "end_pos": 4062321, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010059726.1", "url": "https://www.ensembl.org/id/ENSGALT00010059726.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010036488.1", "url": "https://www.ensembl.org/id/ENSGALP00010036488.1" } ] } }, { "isoform_ac": "A0A8V1A1U7-1", "url": "https://www.uniprot.org/uniprotkb/F1NQJ6/entry#A0A8V1A1U7-1", "sequence": { "sequence": "MRGAPAVPFVPRPPLLPPGAEECGTAALLFAPGAAWPGAVLAAVCRSNKSPWVCLTCSSVHCGRYVNGHAKKHYEDAQIPMTNHKKTEKQEKVQHTVCMDCSSYSTYCYRCDDFVVNDTKLGLVQKVREHLQNLENSAFTSDRHRKRKLLENSSLNSKLLKVNGSTTALCATGLRNLGNTCFMNAILQSLSNIQQFCCYFKELPAVELRNGKTAGRRTYHTRSQGDNNVSLVEEFRKTLCALWQGSQTAFSPESLFYVVWKIMPNFRGYQQQDAHEFMRYLLDHLHLELQGGFNGVSRSVILQENSSLTASSKCCINGASTVVTAIFGGILQNEVNCLICGTESRKFDPFLDLSLDIPSQFRNKRTKNQENGPMCTLRDCLRSFTDLEELDETELYMCHKCKKKQKSTKKFWIQKLPKVLCLHLKRFHWTAYLRNKVDTYVEFPLRGLDMKCYLLEPENSGPESCLYDLAAVVVHHGSGVGSGHYTAYAAHEGRWFHFNDSTVTLTDEETVVKAKAYILFYVERQAKSGSDKL", "length": 533, "header": "tr|A0A8V1A1U7-1|A0A8V1A1U7_CHICK Computationally mapped isoform of Ubiquitin carboxyl-terminal hydrolase OS=Gallus gallus OX=9031 GN=USP3 PE=3 SV=1 CANONICAL=F1NQJ6-1" }, "locus": { "chromosome": "10", "start_pos": 4095250, "end_pos": 4062321, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010059718.1", "url": "https://www.ensembl.org/id/ENSGALT00010059718.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010036482.1", "url": "https://www.ensembl.org/id/ENSGALP00010036482.1" } ] } }, { "isoform_ac": "A0A8V1A5A7-1", "url": "https://www.uniprot.org/uniprotkb/F1NQJ6/entry#A0A8V1A5A7-1", "sequence": { "sequence": "MECPHLGSSVCIAPDSAKFPQGSPSSWCCSVCRSNKSPWVCLTCSSVHCGRYVNGHAKKHYEDAQIPMTNHKKTEKQEKVQHTVCMDCSSYSTYCYRCDDFVVNDTKLGLVQKVREHLQNLENSAFTSDRHRKRKLLENSSLNSKLLKVNGSTTALCATGLRNLGNTCFMNAILQSLSNIQQFCCYFKELPAVELRNGKTAGRRTYHTRSQGDNNVSLVEEFRKTLCALWQGSQTAFSPESLFYVVWKIMPNFRNGASTVVTAIFGGILQNEVNCLICGTESRKFDPFLDLSLDIPSQFRNKRTKNQENGPMCTLRDCLRSFTDLEELDETELYMCHKCKKKQKSTKKFWIQKLPKVLCLHLKRFHWTAYLRNKVDTYVEFPLRGLDMKCYLLEPENSGPESCLYDLAAVVVHHGSGVGSGHYTAYAAHEGRWFHFNDSTVTLTDEETVVKAKAYILFYVERQAKSGSDKL", "length": 471, "header": "tr|A0A8V1A5A7-1|A0A8V1A5A7_CHICK Computationally mapped isoform of Ubiquitin carboxyl-terminal hydrolase OS=Gallus gallus OX=9031 GN=USP3 PE=3 SV=1 CANONICAL=F1NQJ6-1" }, "locus": { "chromosome": "10", "start_pos": 4095716, "end_pos": 4062321, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010059722.1", "url": "https://www.ensembl.org/id/ENSGALT00010059722.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010036485.1", "url": "https://www.ensembl.org/id/ENSGALP00010036485.1" } ] } }, { "isoform_ac": "F1NQJ6-1", "url": "https://www.uniprot.org/uniprotkb/F1NQJ6/entry#F1NQJ6-1", "sequence": { "sequence": "MECPHLGSSVCIAPDSAKFPQGSPSSWCCSVCRSNKSPWVCLTCSSVHCGRYVNGHAKKHYEDAQIPMTNHKKTEKQEKVQHTVCMDCSSYSTYCYRCDDFVVNDTKLGLVQKVREHLQNLENSAFTSDRHRKRKLLENSSLNSKLLKVNGSTTALCATGLRNLGNTCFMNAILQSLSNIQQFCCYFKELPAVELRNGKTAGRRTYHTRSQGDNNVSLVEEFRKTLCALWQGSQTAFSPESLFYVVWKIMPNFRGYQQQDAHEFMRYLLDHLHLELQGGFNGVSRSVILQENSSLTASSKCCINGASTVVTAIFGGILQNEVNCLICGTESRKFDPFLDLSLDIPSQFRNKRTKNQENGPMCTLRDCLRSFTDLEELDETELYMCHKCKKKQKSTKKFWIQKLPKVLCLHLKRFHWTAYLRNKVDTYVEFPLRGLDMKCYLLEPENSGPESCLYDLAAVVVHHGSGVGSGHYTAYAAHEGRWFHFNDSTVTLTDEETVVKAKAYILFYVERQAKSGSDKL", "length": 520, "header": "tr|F1NQJ6-1|F1NQJ6_CHICK Isoform 1 of Ubiquitin carboxyl-terminal hydrolase OS=Gallus gallus OX=9031 GN=USP3 PE=3 SV=4 CANONICAL=F1NQJ6-1" }, "locus": { "chromosome": "10", "start_pos": 4095716, "end_pos": 4062321, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010059730.1", "url": "https://www.ensembl.org/id/ENSGALT00010059730.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010036491.1", "url": "https://www.ensembl.org/id/ENSGALP00010036491.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "R-GGA-5689880", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5689880", "resource": "Reactome", "description": "Ub-specific processing proteases" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A480K0Z8-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase", "gene_name": "USP3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MECPHLSSSVCIAPDSAKFPNGSPSSWCCSVCRSNKSPWVCLTCSSVHCGRYVNGHAKKHYEDAQIPLTNHKKSEKQEKAQHTVCMDCSSYSTYCYRCDDFVVNDTKLGLVQKVREHLQNLENSAFTADRHRKRKLLENSSLNSKLLKVNGSTTAICATGLRNLGNTCFMNAILQSLSNIEQFCCYFKELPAVELRNGKTAGRRTYHTRSQGDNNVSLVEEFRKTLCALWQGSQTAFSPESLFYVVWKIMPNFRGYQQQDAHEFMRYLLDHLHLELQGGFNGISRSSILQENSTLSASNKCCINGASTVVTAIFGGILQNEVNCLICGTESRKFDPFLDLSLDIPSQFRNKRSKNQENGPVCSLRDCLRSFTDLEELDETELYMCHKCKKKQKSTKKFWIQKLPKVLCLHLKRFHWTAYLRNKVDTYVEFPLRGLDMKCYLLEPENSGPENCLYDLAAVVVHHGSGVGSGHYTAYATHEGRWFHFNDSTVTLTDEDTVVKAKAYILFYVERQAKAGSDKL", "length": 520 }, "evidence": [ { "id": "F1NQJ6", "url": "https://omabrowser.org/oma/group/F1NQJ6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0ABK0M1L0-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 3", "gene_name": "Usp3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MECPHLSSSVCIAPDSAKFPNGSPSSWCCSVCRSNKSPWVCLTCSSVHCGRYVNGHAKKHYEDAQIPLLNHKRSEKQEKAQHTVCMDCSSYSTYCYRCDDFVVNDTKLGLVQKVREHLQNLENSAFTADRHRKRKLLENSSLNSKLLKVNGSTAAICATGLRNLGNTCFMNAILQSLSNIEQFCCYFKELPAVELRNGKTAGRRTYHTRSQGDSNVSLVEEFRKTLCALWQGSQTAFSPESLFYVVWKIMPNFRGYQQQDAHEFMRYLLDHLHLELQGGFNGVSRSAILQENSTLSANNKCCINGASTVVTTIFGGILQNEVNCLICGTESRKFDPFLDLSLDIPSQFRSKRSKNQENGPVCSLRDCLRSFTDLEELDETELYMCHKCKKKQKSTKKFWIQKLPKALCLHLKRFHWTAYLRNKVDTYVQFPLRGLDMKCYLLEPENSGPDSCLYDLAAVVVHHGSGLIKKLFYFQTWTSILGPAITHISVLLSLQTWFDQLVIAGWFWALHSICSSRRPLVPFQ", "length": 524 }, "evidence": [ { "id": "F1NQJ6", "url": "https://omabrowser.org/oma/group/F1NQJ6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q91W36-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 3", "gene_name": "Usp3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MECPHLSSSVCIAPDSAKFPNGSPSSWCCSVCRSNKSPWVCLTCSSVHCGRYVNGHAKKHYEDAQIPLLNHKRSEKQEKAQHTVCMDCSSYSTYCYRCDDFVVNDTKLGLVQKVREHLQNLENSAFTADRHRKRKLLENSSLNSKLLKVNGSTTAICATGLRNLGNTCFMNAILQSLSNIEQFCCYFKELPAVELRNGKTAGRRTYHTRSQGDSNVSLVEEFRKTLCALWQGSQTAFSPESLFYVVWKIMPNFRGYQQQDAHEFMRYLLDHLHLELQGGFNGVSRSAILQENSTLSASNKCCINGASTVVTAIFGGILQNEVNCLICGTESRKFDPFLDLSLDIPSQFRSKRSKNQENGPVCSLRDCLRSFTDLEELDETELYMCHKCKKKQKSTKKFWIQKLPKALCLHLKRFHWTAYLRNKVDTYVQFPLRGLDMKCYLLEPENSGPDSCLYDLAAVVVHHGSGVGSGHYTAYAVHEGRWFHFNDSTVTVTDEETVGKAKAYILFYVERQARAGAEKL", "length": 520 }, "evidence": [ { "id": "F1NQJ6", "url": "https://omabrowser.org/oma/group/F1NQJ6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9Y6I4-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 3", "gene_name": "USP3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MECPHLSSSVCIAPDSAKFPNGSPSSWCCSVCRSNKSPWVCLTCSSVHCGRYVNGHAKKHYEDAQVPLTNHKKSEKQDKVQHTVCMDCSSYSTYCYRCDDFVVNDTKLGLVQKVREHLQNLENSAFTADRHKKRKLLENSTLNSKLLKVNGSTTAICATGLRNLGNTCFMNAILQSLSNIEQFCCYFKELPAVELRNGKTAGRRTYHTRSQGDNNVSLVEEFRKTLCALWQGSQTAFSPESLFYVVWKIMPNFRGYQQQDAHEFMRYLLDHLHLELQGGFNGVSRSAILQENSTLSASNKCCINGASTVVTAIFGGILQNEVNCLICGTESRKFDPFLDLSLDIPSQFRSKRSKNQENGPVCSLRDCLRSFTDLEELDETELYMCHKCKKKQKSTKKFWIQKLPKVLCLHLKRFHWTAYLRNKVDTYVEFPLRGLDMKCYLLEPENSGPESCLYDLAAVVVHHGSGVGSGHYTAYATHEGRWFHFNDSTVTLTDEETVVKAKAYILFYVEHQAKAGSDKL", "length": 520 }, "evidence": [ { "id": "F1NQJ6", "url": "https://omabrowser.org/oma/group/F1NQJ6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "X1WG21-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase", "gene_name": "usp3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MECPHLNSSVCMTVDLTRFPNGSPSSWCCSVCRSNKSPWVCLTCMNVHCGRYVNGHAKKHFEEIEAPGCSQRKPDREKLREKGQQHSVCMDCNSYSTFCYKCDEFVVNDTKLGHVQRVREHLQSLENSVCNTDRQRKRKMSESFSPDSKMKQDSEGALVQCATGLRNLGNTCFMNAILQSLSNIQVFSCYFKELPSVALRSGKTAGRRMYHTRSQGDSSVSLVEEFRKTLCSLWQGSQTAFSPDALFYVIWKIMPSFRGYQQQDAHEFLRYLLDHLHREMQGNKNGSPSPPVTSDEPNHASESKCFINGTSTIVTSVFGGVLQNEVYCLICGTESRKFDPFLDLSLDIPNQFRIKTTKDQEPGPTCTLSDCLRSFTDLEELDETELYMCHKCKKRQKSTKKFWIQKLPKVLCLHLKRFHWTAFLRNKVDTYVEFPMCGLDMKSYLLEPENSLPERCLYDLAAVVVHHGSGIGSGHYTAYGRHEGQWYHFNDSTVTLVSEEAVLKAKAYILFYTEHSDRESQSKL", "length": 524 }, "evidence": [ { "id": "F1NQJ6", "url": "https://omabrowser.org/oma/group/F1NQJ6/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "F1NQJ6", "url": "https://www.uniprot.org/uniprotkb/F1NQJ6" } ], "pmid": "" }, { "name": "protein deubiquitination", "id": "GO:0016579", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016579", "evidence": [ { "database": "UniProtKB", "id": "F1NQJ6", "url": "https://www.uniprot.org/uniprotkb/F1NQJ6" } ], "pmid": "" }, { "name": "DNA repair", "id": "GO:0006281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006281", "evidence": [ { "database": "UniProtKB", "id": "F1NQJ6", "url": "https://www.uniprot.org/uniprotkb/F1NQJ6" } ], "pmid": "" }, { "name": "DNA repair-dependent chromatin remodeling", "id": "GO:0140861", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140861", "evidence": [ { "database": "UniProtKB", "id": "F1NQJ6", "url": "https://www.uniprot.org/uniprotkb/F1NQJ6" } ], "pmid": "" }, { "name": "DNA damage response", "id": "GO:0006974", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006974", "evidence": [ { "database": "UniProtKB", "id": "F1NQJ6", "url": "https://www.uniprot.org/uniprotkb/F1NQJ6" } ], "pmid": "" }, { "name": "chromatin organization", "id": "GO:0006325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006325", "evidence": [ { "database": "UniProtKB", "id": "F1NQJ6", "url": "https://www.uniprot.org/uniprotkb/F1NQJ6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "F1NQJ6", "url": "https://www.uniprot.org/uniprotkb/F1NQJ6" } ], "pmid": "" }, { "name": "cysteine-type deubiquitinase activity", "id": "GO:0004843", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004843", "evidence": [ { "database": "UniProtKB", "id": "F1NQJ6", "url": "https://www.uniprot.org/uniprotkb/F1NQJ6" } ], "pmid": "" }, { "name": "histone binding", "id": "GO:0042393", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042393", "evidence": [ { "database": "UniProtKB", "id": "F1NQJ6", "url": "https://www.uniprot.org/uniprotkb/F1NQJ6" } ], "pmid": "" }, { "name": "histone H2B deubiquitinase activity", "id": "GO:0140936", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140936", "evidence": [ { "database": "UniProtKB", "id": "F1NQJ6", "url": "https://www.uniprot.org/uniprotkb/F1NQJ6" } ], "pmid": "" }, { "name": "histone H2A deubiquitinase activity", "id": "GO:0140950", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140950", "evidence": [ { "database": "UniProtKB", "id": "F1NQJ6", "url": "https://www.uniprot.org/uniprotkb/F1NQJ6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1NQJ6", "url": "https://www.uniprot.org/uniprotkb/F1NQJ6" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "F1NQJ6", "url": "https://www.uniprot.org/uniprotkb/F1NQJ6" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1NQJ6", "url": "https://www.uniprot.org/uniprotkb/F1NQJ6" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "F1NQJ6", "url": "https://www.uniprot.org/uniprotkb/F1NQJ6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 104, "end_pos": 106, "annotation": "n_glycosylation_sequon" }, { "start_pos": 139, "end_pos": 141, "annotation": "n_glycosylation_sequon" }, { "start_pos": 150, "end_pos": 152, "annotation": "n_glycosylation_sequon" }, { "start_pos": 215, "end_pos": 217, "annotation": "n_glycosylation_sequon" }, { "start_pos": 292, "end_pos": 294, "annotation": "n_glycosylation_sequon" }, { "start_pos": 35, "end_pos": 37, "annotation": "n_glycosylation_sequon" }, { "start_pos": 486, "end_pos": 488, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-GGA-5690080", "name": "USP3,SAGA deubiquitinate Histone H2A,H2B", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1NQJ6-1", "A0A8V0ZTT2-1" ], "evidence": [ { "id": "R-GGA-5690080", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5690080" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A8V0ZTT2", "gene_name": "KAT2A", "activity": [ { "ec_number": "2.3.1.48", "activity": "L-lysyl-[histone] + acetyl-CoA = N(6)-acetyl-L-lysyl-[histone] + CoA + H(+).", "evidence": [ { "id": "A0A8V0ZTT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTT2" } ] }, { "ec_number": "2.3.1.48", "activity": "", "evidence": [ { "id": "A0A8V0ZTT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTT2" } ] } ] }, { "uniprot_ac": "F1NQJ6", "gene_name": "USP3", "activity": [ { "ec_number": "3.4.19.12", "activity": "Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).", "evidence": [ { "id": "F1NQJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NQJ6" } ] }, { "ec_number": "3.4.19.12", "activity": "", "evidence": [ { "id": "F1NQJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NQJ6" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "3.4.19.12", "ec_name": "Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).", "evidence": [ { "id": "3.4.19.12", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=3.4.19.12" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 104, "end_pos": 106 }, { "start_pos": 139, "end_pos": 141 }, { "start_pos": 150, "end_pos": 152 }, { "start_pos": 215, "end_pos": 217 }, { "start_pos": 292, "end_pos": 294 }, { "start_pos": 35, "end_pos": 37 }, { "start_pos": 486, "end_pos": 488 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1NL99-1", "uniprot_ac": "F1NL99", "uniprot_id": "F1NL99_CHICK", "mass": { "chemical_mass": 16749.0, "monoisotopic_mass": 16749.0 }, "refseq": { "ac": "XP_417928", "name": "6-pyruvoyl tetrahydrobiopterin synthase isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_417928" }, "gene_names": [ { "name": "PTS", "type": "recommended", "evidence": [ { "id": "F1NL99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NL99" } ] }, { "name": "PTS", "type": "synonym", "evidence": [ { "id": "XP_417928", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_417928" } ] } ], "protein_names": [ { "name": "6-pyruvoyl tetrahydrobiopterin synthase", "type": "recommended", "evidence": [ { "id": "F1NL99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NL99/entry#names_and_taxonomy" } ] }, { "name": "4.2.3.12", "type": "synonym", "evidence": [ { "id": "F1NL99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NL99/entry#names_and_taxonomy" } ] }, { "name": "6-pyruvoyl tetrahydrobiopterin synthase isoform X1", "type": "synonym", "evidence": [ { "id": "XP_417928", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_417928" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052555.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process On Nov 16, 2006 this sequence version replaced XP_417928.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_417928", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_417928" } ] }, { "annotation": "Involved in the biosynthesis of tetrahydrobiopterin, an essential cofactor of aromatic amino acid hydroxylases. Catalyzes the transformation of 7,8-dihydroneopterin triphosphate into 6-pyruvoyl tetrahydropterin.", "evidence": [ { "database": "UniProtKB", "id": "F1NL99", "url": "https://www.uniprot.org/uniprotkb/F1NL99#function" }, { "database": "UniProtKB", "id": "ARBA00025266", "url": "https://www.uniprot.org/uniprotkb/ARBA00025266#function" }, { "database": "UniProtKB", "id": "A0A8V1A5P5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5P5#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NL99", "url": "https://www.uniprot.org/uniprotkb/F1NL99" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PTS", "url": "https://www.uniprot.org/uniprotkb/F1NL99", "locus": { "chromosome": "24", "start_pos": 6161620, "end_pos": 6165927, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010024986", "url": "https://www.ensembl.org/id/ENSGALG00010024986" } ] } } ], "crossref": [ { "id": "F1NL99", "url": "https://alphafold.ebi.ac.uk/entry/F1NL99", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000007848", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000007848", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00470", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00470", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "374144", "url": "https://www.ncbi.nlm.nih.gov/gene/374144", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR007115", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007115", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR022469", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022469", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR022470", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022470", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038418", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038418", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "YETERNF", "url": "https://omabrowser.org/oma/group/YETERNF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A5P5", "url": "https://www.orthodb.org/?gene=A0A8V1A5P5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NL99", "url": "https://www.orthodb.org/?gene=F1NL99", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12589", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12589", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12589:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12589:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01242", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01242", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-1474151", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1474151", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_417928", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_417928", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1A5P5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5P5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A5P5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5P5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NL99", "url": "https://www.uniprot.org/uniprotkb/F1NL99", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NL99-1", "url": "https://www.uniprot.org/uniprotkb/F1NL99-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAPPAARLARLSRTASFSACHRLHSKSLSDEENLKLFGKCNNPNGHGHNYKVIVTVRGEIDPVSGMVINLTDLKEYMQQAIMEPLDHKNLDKDVPYFAEVVSTTENVAVFIWENLKRLLPAGMLYKVKVYETDQNIVVYKGEETISER", "length": 148, "header": "tr|F1NL99-1|F1NL99_CHICK Isoform 1 of 6-pyruvoyl tetrahydrobiopterin synthase OS=Gallus gallus OX=9031 GN=PTS PE=1 SV=2 CANONICAL=F1NL99-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A5P5-1", "url": "https://www.uniprot.org/uniprotkb/F1NL99/entry#A0A8V1A5P5-1", "sequence": { "sequence": "MAPPAARLARLSRTASFSACHRLHSKSLSDEENLKLFGKCNNPNGHGHNYKVIVTVRGEIDPVSGMVINLTDLKEYMQQAIMEPLDHKNLDKDVPYFAEVVRWVEVWGAAGSGCSLRGSDLSWGSAVSAIADGSESAAVSLSAPQRTLQCSSGKTSRGSCLRECFIKSKCMKRTRTLWSIKEKKQFLRGEMSRSSAGQKLTPAHVSDTVSPACCVLKQSLGYALQKNQPR", "length": 230, "header": "tr|A0A8V1A5P5-1|A0A8V1A5P5_CHICK Computationally mapped isoform of 6-pyruvoyl tetrahydrobiopterin synthase OS=Gallus gallus OX=9031 GN=PTS PE=1 SV=1 CANONICAL=F1NL99-1" }, "locus": { "chromosome": "24", "start_pos": 6164227, "end_pos": 6161765, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010061023.1", "url": "https://www.ensembl.org/id/ENSGALT00010061023.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010037759.1", "url": "https://www.ensembl.org/id/ENSGALP00010037759.1" } ] } }, { "isoform_ac": "F1NL99-1", "url": "https://www.uniprot.org/uniprotkb/F1NL99/entry#F1NL99-1", "sequence": { "sequence": "MAPPAARLARLSRTASFSACHRLHSKSLSDEENLKLFGKCNNPNGHGHNYKVIVTVRGEIDPVSGMVINLTDLKEYMQQAIMEPLDHKNLDKDVPYFAEVVSTTENVAVFIWENLKRLLPAGMLYKVKVYETDQNIVVYKGEETISER", "length": 148, "header": "tr|F1NL99-1|F1NL99_CHICK Isoform 1 of 6-pyruvoyl tetrahydrobiopterin synthase OS=Gallus gallus OX=9031 GN=PTS PE=1 SV=2 CANONICAL=F1NL99-1" }, "locus": { "chromosome": "24", "start_pos": 6164227, "end_pos": 6161889, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010061021.1", "url": "https://www.ensembl.org/id/ENSGALT00010061021.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010037758.1", "url": "https://www.ensembl.org/id/ENSGALP00010037758.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "R-GGA-1474151", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1474151", "resource": "Reactome", "description": "Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation" } ], "orthologs": [ { "uniprot_canonical_ac": "F1MX94-1", "protein_name": "6-pyruvoyl tetrahydrobiopterin synthase", "gene_name": "PTS", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MNGAGSGPRRRARVSRLVSFSATHRLHSKSLSNEENLKLFGKCNNPNGHGHNYKVVVTVHGEVDPVTGMVMNLTDLKKYMEEAIMKPLDHKNLDLDVPYFADIVSTTENVAVYIWENLQKFLPVGVLYKVKVYETDNNIVVYKGE", "length": 145 }, "evidence": [ { "id": "F1NL99", "url": "https://omabrowser.org/oma/group/F1NL99/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1SM93-1", "protein_name": "6-pyruvoyl tetrahydrobiopterin synthase", "gene_name": "PTS", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRSDADSGPHRRARVSRLASFSASHRLHSKSLSNEENLKLFGKCNNPNGHGHNYKVVVTVHGEIDPVTGMVMNLTDLKKYMEEAIMKPLDHKNLDLDVPYFADVVSTTENVAVYIWENLQKYLPAGVLYKVKVYETDNNIVVYKGE", "length": 146 }, "evidence": [ { "id": "F1NL99", "url": "https://omabrowser.org/oma/group/F1NL99/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3H2I2-1", "protein_name": "6-pyruvoyl tetrahydrobiopterin synthase", "gene_name": "Pts", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSVAGGFRRRARLSRLVSFSASHRLHSPSLSDEENLKVFGKCNNPNGHGHNYKVVVTVHGEVDPVTGMVMNLTDLKEYMEEAIMKPLDHKNLDLDVPYFAGVVSTTENVAVYIWESLQKLLPTGVLYKVKVYETDNNIVVYKGE", "length": 144 }, "evidence": [ { "id": "F1NL99", "url": "https://omabrowser.org/oma/group/F1NL99/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q03393-1", "protein_name": "6-pyruvoyl tetrahydrobiopterin synthase", "gene_name": "PTS", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSTEGGGRRCQAQVSRRISFSASHRLYSKFLSDEENLKLFGKCNNPNGHGHNYKVVVTVHGEIDPATGMVMNLADLKKYMEEAIMQPLDHKNLDMDVPYFADVVSTTENVAVYIWDNLQKVLPVGVLYKVKVYETDNNIVVYKGE", "length": 145 }, "evidence": [ { "id": "F1NL99", "url": "https://omabrowser.org/oma/group/F1NL99/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9R1Z7-1", "protein_name": "6-pyruvoyl tetrahydrobiopterin synthase", "gene_name": "Pts", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAAGDLRRRARLSRLVSFSASHRLHSPSLSDEENLRVFGKCNNPNGHGHNYKVVVTVHGEIDPVTGMVMNLTDLKEYMEEAIMKPLDHKNLDLDVPYFADAVSTTENVAVYIWESLQKLLPVGALYKVKVFETDNNIVVYKGE", "length": 144 }, "evidence": [ { "id": "F1NL99", "url": "https://omabrowser.org/oma/group/F1NL99/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "F1NL99", "url": "https://www.uniprot.org/uniprotkb/F1NL99" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "F1NL99", "url": "https://www.uniprot.org/uniprotkb/F1NL99" } ], "pmid": "" }, { "name": "6-pyruvoyltetrahydropterin synthase activity", "id": "GO:0003874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003874", "evidence": [ { "database": "UniProtKB", "id": "F1NL99", "url": "https://www.uniprot.org/uniprotkb/F1NL99" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "tetrahydrobiopterin biosynthetic process", "id": "GO:0006729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006729", "evidence": [ { "database": "UniProtKB", "id": "F1NL99", "url": "https://www.uniprot.org/uniprotkb/F1NL99" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 69, "end_pos": 71, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-GGA-1474184", "name": "DHNTP is dephosphorylated by PTPS to PTHP", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [ "R-ALL-1474179", "R-ALL-1475054" ], "enzyme_list": [ "F1NL99-1" ], "evidence": [ { "id": "R-GGA-1474184", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1474184" } ] }, { "id": "R-GGA-1475422", "name": "PTPS is phosphorylated by cGMP-dependant protein kinase II", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XCS0-1", "F1NL99-1" ], "evidence": [ { "id": "R-GGA-1475422", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1475422" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-1474179", "participant_name": "PTHP [cytosol]", "crossref": [ { "id": "ZINC000100028524", "database": "ZINC", "url": "" }, { "id": "HMDB0001195", "database": "HMDB Metabolite", "url": "" }, { "id": "17804", "database": "ChEBI", "url": "" }, { "id": "C03684", "database": "COMPOUND", "url": "" }, { "id": "ZINC000013513777", "database": "ZINC", "url": "" } ] }, { "participant_id": "R-ALL-1475054", "participant_name": "PPP [cytosol]", "crossref": [ { "id": "15266", "database": "ChEBI", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A0A8V0XCS0", "gene_name": "PRKG2", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XCS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCS0" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "A0A8V0XCS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCS0" } ] } ] }, { "uniprot_ac": "F1NL99", "gene_name": "PTS", "activity": [ { "ec_number": "4.2.3.12", "activity": "7,8-dihydroneopterin 3'-triphosphate = 6-pyruvoyl-5,6,7,8-tetrahydropterin + triphosphate + H(+).", "evidence": [ { "id": "F1NL99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NL99" } ] }, { "ec_number": "4.2.3.12", "activity": "", "evidence": [ { "id": "F1NL99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NL99" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "4.2.3.12", "ec_name": "7,8-dihydroneopterin 3'-triphosphate = 6-pyruvoyl-5,6,7,8-tetrahydropterin + triphosphate + H(+).", "evidence": [ { "id": "4.2.3.12", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.3.12" }, { "id": "4.2.3.12", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=4.2.3.12" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 69, "end_pos": 71 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1NG97-1", "uniprot_ac": "F1NG97", "uniprot_id": "F1NG97_CHICK", "mass": { "chemical_mass": 88931.0, "monoisotopic_mass": 88931.0 }, "refseq": { "ac": "NP_001186517", "name": "AMP deaminase 3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186517" }, "gene_names": [ { "name": "AMPD3", "type": "recommended", "evidence": [ { "id": "F1NG97", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NG97" } ] }, { "name": "AMPD3", "type": "synonym", "evidence": [ { "id": "NP_001186517", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186517" } ] } ], "protein_names": [ { "name": "AMP deaminase", "type": "recommended", "evidence": [ { "id": "F1NG97", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NG97/entry#names_and_taxonomy" } ] }, { "name": "3.5.4.6", "type": "synonym", "evidence": [ { "id": "F1NG97", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NG97/entry#names_and_taxonomy" } ] }, { "name": "AMP deaminase 3", "type": "synonym", "evidence": [ { "id": "NP_001186517", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186517" } ] }, { "name": "adenosine monophosphate deaminase (isoform E)", "type": "synonym", "evidence": [ { "id": "NP_001186517", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186517" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: SRR13267654.218581.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA103992290, SAMEA103992323 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000214.1. On Dec 10, 2010 this sequence version replaced XP_420973.2. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001186517", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186517" } ] }, { "annotation": "AMP deaminase plays a critical role in energy metabolism. Catalyzes the deamination of AMP to IMP and plays an important role in the purine nucleotide cycle.", "evidence": [ { "database": "UniProtKB", "id": "F1NG97", "url": "https://www.uniprot.org/uniprotkb/F1NG97#function" }, { "database": "UniProtKB", "id": "ARBA00054146", "url": "https://www.uniprot.org/uniprotkb/ARBA00054146#function" }, { "database": "UniProtKB", "id": "A0A8V0ZAB9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAB9#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NG97", "url": "https://www.uniprot.org/uniprotkb/F1NG97" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "AMPD3", "url": "https://www.uniprot.org/uniprotkb/F1NG97", "locus": { "chromosome": "5", "start_pos": 8588981, "end_pos": 8618006, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021085", "url": "https://www.ensembl.org/id/ENSGALG00010021085" } ] } } ], "crossref": [ { "id": "F1NG97", "url": "https://alphafold.ebi.ac.uk/entry/F1NG97", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000005662", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000005662", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd01319", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01319", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "423041", "url": "https://www.ncbi.nlm.nih.gov/gene/423041", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006329", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006329", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006650", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006650", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032466", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032466", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:423041", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423041", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "GNAGPEC", "url": "https://omabrowser.org/oma/group/GNAGPEC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZAB9", "url": "https://www.orthodb.org/?gene=A0A8V0ZAB9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZG20", "url": "https://www.orthodb.org/?gene=A0A8V0ZG20", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZHD3", "url": "https://www.orthodb.org/?gene=A0A8V0ZHD3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NG97", "url": "https://www.orthodb.org/?gene=F1NG97", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11359", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11359", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11359:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11359:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF19326", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19326", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-6798695", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6798695", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-74217", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-74217", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001186517", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186517", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "14777", "url": "https://www.rhea-db.org/rhea/14777", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0ZAB9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAB9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZAB9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAB9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZG20", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG20", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZG20-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG20-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZHD3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHD3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZHD3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHD3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NG97", "url": "https://www.uniprot.org/uniprotkb/F1NG97", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NG97-1", "url": "https://www.uniprot.org/uniprotkb/F1NG97-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPRQFPKLNISEDDVQVRLQAEKVFATVLREEDSKDALSLFTVPEDCPIGQTEAKERELQKELAEQQSVETAKRKKSFKMIRSQSLSLQIPSQEWKAPSAIPTVSPTTPVLQSAFLPVQVPYDVPEFQRVSISGDYCAGVTVDDYEQAAKRLVKALLIREKYSRLAYHRFPRTTSQYLCSMQHEKWKVEDEVCPYFHSPPEENEDPYNLDDAPDNLDYVVKIKGGIPFVYDNKEMMELNEPRSLPYPDLETYTLDLSHVLALIADGPTKTYCHRRLNFLESKFSLHEMLNEMSEFKELKSNPHRDFYNVRKVDTHIHAAACMNQKHLLRFIKHTYQTESDRIVAEKKGKKMTLKQVFESLHMDPYDLTVDSLDVHAGRQTFHRFDKFNSKYNPVGASELRDLYLKTENYIGGEYFARMVKEVALELEESKYQYTEPRLSIYGRSPDEWQNLAKWFIKHKVYSPNMRWIIQVPRIYDIFRSKNILPNFGKMLENVFVPLFEATINPKDHKELHLFLKYVTGFDSVDDESKHSGHMFSEKSLNPDLWTSEKNPPYSYYLYYMYVNIMLLNNLRQERGMCTFLFRPHCGEAGSITHLVSAFLTADNISHGLLLKKSPVLQYLYYLAQIPIAMSPLSNNSLFLEYSKNPLREFLHKGLHVSLSTDDPMQFHYTKEALMEEYAIAAQVWKLSTCDLCEIARNSVLQSGLSDKEKQKFLGVNYCKEGPEGNDIRKTNVAQIRMAFRYETLCNELSFLSDAMRTDEISTLSK", "length": 765, "header": "tr|F1NG97-1|F1NG97_CHICK Isoform 1 of AMP deaminase OS=Gallus gallus OX=9031 GN=AMPD3 PE=1 SV=2 CANONICAL=F1NG97-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZAB9-1", "url": "https://www.uniprot.org/uniprotkb/F1NG97/entry#A0A8V0ZAB9-1", "sequence": { "sequence": "MRHRRTVAAAASGGSGSSLYSSSPPAPERASRSGSGVGPGMEFPGELAEMPRQFPKLNISEDDVQVRLQAEKVFATVLREEDSKDALSLFTVPEDCPIGQTEAKERELQKELAEQQSVETAKRKKSFKMIRSQSLSLQIPSQEWKAPSAIPTVSPTTPVLQSAFLPVQVPYDVPEFQRVSISGDYCAGVTVDDYEQAAKRLVKALLIREKYSRLAYHRFPRTTSQYLCSMQHEKWKVEDEVCPYFHSPPEENEDPYNLDDAPDNLDYVVKIKGGIPFVYDNKEMMELNEPRSLPYPDLETYTLDLSHVLALIADGPTKTYCHRRLNFLESKFSLHEMLNEMSEFKELKSNPHRDFYNVRKVDTHIHAAACMNQKHLLRFIKHTYQTESDRIVAEKKGKKMTLKQVFESLHMDPYDLTVDSLDVHAGRQTFHRFDKFNSKYNPVGASELRDLYLKTENYIGGEYFARMVKEVALELEESKYQYTEPRLSIYGRSPDEWQNLAKWFIKHKVYSPNMRWIIQVPRIYDIFRSKNILPNFGKMLENVFVPLFEATINPKDHKELHLFLKYVTGFDSVDDESKHSGHMFSEKSLNPDLWTSEKNPPYSYYLYYMYVNIMLLNNLRQERGMCTFLFRPHCGEAGSITHLVSAFLTADNISHGLLLKKSPVLQYLYYLAQIPIAMSPLSNNSLFLEYSKNPLREFLHKGLHVSLSTDDPMQFHYTKEALMEEYAIAAQVWKLSTCDLCEIARNSVLQSGLSDKEKQKFLGVNYCKEGPEGNDIRKTNVAQIRMAFRYETLCNELSFLSDAMRTDEISTLSK", "length": 814, "header": "tr|A0A8V0ZAB9-1|A0A8V0ZAB9_CHICK Computationally mapped isoform of AMP deaminase OS=Gallus gallus OX=9031 GN=AMPD3 PE=1 SV=1 CANONICAL=F1NG97-1" }, "locus": { "chromosome": "5", "start_pos": 8617463, "end_pos": 8592337, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051039.1", "url": "https://www.ensembl.org/id/ENSGALT00010051039.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030230.1", "url": "https://www.ensembl.org/id/ENSGALP00010030230.1" } ] } }, { "isoform_ac": "A0A8V0ZG20-1", "url": "https://www.uniprot.org/uniprotkb/F1NG97/entry#A0A8V0ZG20-1", "sequence": { "sequence": "MPRQFPKLNISEDDVQVRLQAEKVFATVLREEDSKDALSLFTVPEDCPIGQTEAKERELQKELAEQQSVETAKRKKSFKMIRSQSLSLQIPSQEWKAPSAIPTVSPTTPVLQSAFLPVQVPYDVPEFQRVSISGDYCAGVTVDDYEQAAKRLVKALLIREKYSRLAYHRFPRTTSQYLCSMQHEKWKVEDEVCPYFHSPPEENEDPYNLDDAPDNLDYVVKIKGGIPFVYDNKEMMELNEPRSLPYPDLETYTLDLSHVLALIADGPTKTYCHRRLNFLESKFSLHEMLNEMSEFKELKSNPHRDFYNVRKVDTHIHAAACMNQKHLLRFIKHTYQTESDRIVAEKKGKKMTLKQVFESLHMDPYDLTVDSLDVHAGRQTFHRFDKFNSKYNPVGASELRDLYLKTENYIGGEYFARMVKEVALELEESKYQYTEPRLSIYGRSPDEWQNLAKWFIKHKVYSPNMRWIIQVPRIYDIFRSKNILPNFGKMLENVFVPLFEATINPKDHKELHLFLKYVTGFDSVDDESKHSGHMFSEKSLNPDLWTSEKNPPYSYYLYYMYVNIMLLNNLRQERGMCTFLFRPHCGEAGSITHLVSAFLTADNISHGLLLKKSPVLQYLYYLAQIPIAMSPLSNNSLFLEYSKNPLREFLHKGLHVSLSTDDPMQFHYTKVRIVKITYLLKLAAVLRRPRMT", "length": 692, "header": "tr|A0A8V0ZG20-1|A0A8V0ZG20_CHICK Computationally mapped isoform of AMP deaminase OS=Gallus gallus OX=9031 GN=AMPD3 PE=1 SV=1 CANONICAL=F1NG97-1" }, "locus": { "chromosome": "5", "start_pos": 8614736, "end_pos": 8594524, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051036.1", "url": "https://www.ensembl.org/id/ENSGALT00010051036.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030227.1", "url": "https://www.ensembl.org/id/ENSGALP00010030227.1" } ] } }, { "isoform_ac": "A0A8V0ZHD3-1", "url": "https://www.uniprot.org/uniprotkb/F1NG97/entry#A0A8V0ZHD3-1", "sequence": { "sequence": "MEFPGELAEMPRQFPKLNISEDDVQVRLQAEKVFATVLREEDSKDALSLFTVPEDCPIGQTEAKERELQKELAEQQSVETAKRKKSFKMIRSQSLSLQIPSQEWKAPSAIPTVSPTTPVLQSAFLPVQVPYDVPEFQRVSISGDYCAGVTVDDYEQAAKRLVKALLIREKYSRLAYHRFPRTTSQYLCSMQHEKWKVEDEVCPYFHSPPEENEDPYNLDDAPDNLDYVVKIKGGIPFVYDNKEMMELNEPRSLPYPDLETYTLDLSHVLALIADGPTKTYCHRRLNFLESKFSLHEMLNEMSEFKELKSNPHRDFYNVRKVDTHIHAAACMNQKHLLRFIKHTYQTESDRIVAEKKGKKMTLKQVFESLHMDPYDLTVDSLDVHAGRQTFHRFDKFNSKYNPVGASELRDLYLKTENYIGGEYFARMVKEVALELEESKYQYTEPRLSIYGRSPDEWQNLAKWFIKHKVYSPNMRWIIQVPRIYDIFRSKNILPNFGKMLENVFVPLFEATINPKDHKELHLFLKYVTGFDSVDDESKHSGHMFSEKSLNPDLWTSEKNPPYSYYLYYMYVNIMLLNNLRQERGMCTFLFRPHCGEAGSITHLVSAFLTADNISHGLLLKKSPVLQYLYYLAQIPIAMSPLSNNSLFLEYSKNPLREFLHKGLHVSLSTDDPMQFHYTKCWLLKYRTKDEAGGRFKPS", "length": 698, "header": "tr|A0A8V0ZHD3-1|A0A8V0ZHD3_CHICK Computationally mapped isoform of AMP deaminase OS=Gallus gallus OX=9031 GN=AMPD3 PE=1 SV=1 CANONICAL=F1NG97-1" }, "locus": { "chromosome": "5", "start_pos": 8617343, "end_pos": 8594314, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051038.1", "url": "https://www.ensembl.org/id/ENSGALT00010051038.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030229.1", "url": "https://www.ensembl.org/id/ENSGALP00010030229.1" } ] } }, { "isoform_ac": "F1NG97-1", "url": "https://www.uniprot.org/uniprotkb/F1NG97/entry#F1NG97-1", "sequence": { "sequence": "MPRQFPKLNISEDDVQVRLQAEKVFATVLREEDSKDALSLFTVPEDCPIGQTEAKERELQKELAEQQSVETAKRKKSFKMIRSQSLSLQIPSQEWKAPSAIPTVSPTTPVLQSAFLPVQVPYDVPEFQRVSISGDYCAGVTVDDYEQAAKRLVKALLIREKYSRLAYHRFPRTTSQYLCSMQHEKWKVEDEVCPYFHSPPEENEDPYNLDDAPDNLDYVVKIKGGIPFVYDNKEMMELNEPRSLPYPDLETYTLDLSHVLALIADGPTKTYCHRRLNFLESKFSLHEMLNEMSEFKELKSNPHRDFYNVRKVDTHIHAAACMNQKHLLRFIKHTYQTESDRIVAEKKGKKMTLKQVFESLHMDPYDLTVDSLDVHAGRQTFHRFDKFNSKYNPVGASELRDLYLKTENYIGGEYFARMVKEVALELEESKYQYTEPRLSIYGRSPDEWQNLAKWFIKHKVYSPNMRWIIQVPRIYDIFRSKNILPNFGKMLENVFVPLFEATINPKDHKELHLFLKYVTGFDSVDDESKHSGHMFSEKSLNPDLWTSEKNPPYSYYLYYMYVNIMLLNNLRQERGMCTFLFRPHCGEAGSITHLVSAFLTADNISHGLLLKKSPVLQYLYYLAQIPIAMSPLSNNSLFLEYSKNPLREFLHKGLHVSLSTDDPMQFHYTKEALMEEYAIAAQVWKLSTCDLCEIARNSVLQSGLSDKEKQKFLGVNYCKEGPEGNDIRKTNVAQIRMAFRYETLCNELSFLSDAMRTDEISTLSK", "length": 765, "header": "tr|F1NG97-1|F1NG97_CHICK Isoform 1 of AMP deaminase OS=Gallus gallus OX=9031 GN=AMPD3 PE=1 SV=2 CANONICAL=F1NG97-1" }, "locus": { "chromosome": "5", "start_pos": 8614736, "end_pos": 8592337, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051040.1", "url": "https://www.ensembl.org/id/ENSGALT00010051040.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030231.1", "url": "https://www.ensembl.org/id/ENSGALP00010030231.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "gga:423041", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423041", "resource": "KEGG Pathway" }, { "id": "R-GGA-6798695", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6798695", "resource": "Reactome", "description": "Neutrophil degranulation" }, { "id": "R-GGA-74217", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-74217", "resource": "Reactome", "description": "Purine salvage" } ], "orthologs": [ { "uniprot_canonical_ac": "O08739-1", "protein_name": "AMP deaminase 3", "gene_name": "Ampd3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPRQFPKLNMSDLDEHVRLLAEKVFAKVLREEDSKDVMSLFTVPEDCPIGQKEAKERELQKELAEQKSVETAKRKKSFKMIRSQSLSLQMPTQQDWKGPPTASPAMSPATPLVPGATSKPGPAPYAMPEYQRVTISGDYCAGITVEDYEQAAKSLAKALMIREKYARLAYHRFPRTTAQYLAHQGESVPLEEGLPDFHPPPLPQEDPYCLDDAPPNLGYLVRMHGGVLFVYDNQTMLERQEPHSLPYPDLETYIVDMSHILALITDGPTKTYCHRRLNFLESKFSLHEMLNEMSEFKELKSNPHRDFYNVRKVDTHIHAAACMNQKHLLRFIKHTYQTEPDRTVAEKLGRKITLRQVFDSLHMDPYDLTVDSLDVHAGRQTFHRFDKFNSKYNPVGASELRDLYLKTENYLGGEYFARMVKEVARELEDSKYQYSEPRLSIYGRSPKEWSSLARWFIQHKVYSPNMRWIIQVPRIYDIFRSKKLLPNFGKMLENIFLPLFKATINPQDHRELHLFLKYVTGFDSVDDESKHSDHMFSDKSPSPDLWTSEQNPPYSYYLYYMYANIMVLNNLRRERGLSTFLFRPHCGEAGSITHLVSAFLTADNISHGLLLKKSPVLQYLYYLAQIPIAMSPLSNNSLFLEYSKNPLREFLHKGLHVSLSTDDPMQFHYTKEALMEEYAIAAQVWKLSTCDLCEIARNSVLQSGLSHQEKQKFLGQNYYKEGPEGNDIRKTNVAQIRMAFRYETLCNELSFLSDAMKSEEITALTK", "length": 766 }, "evidence": [ { "id": "F1NG97", "url": "https://omabrowser.org/oma/group/F1NG97/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "O09178-1", "protein_name": "AMP deaminase 3", "gene_name": "Ampd3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPRQFPKLNMSDLDEHVRLLAEKVFAKVLREEDSKDVMSLFTVPKDCPIGQKEAKERELQKELAEQKSVETAKRKKSFKMIRSQSMSLQMPTQDWKGPPSVSPAMSPTTPLVLGAASKPGLAPYDMPEYQRATISGDYCAGITMEDYEQAAKSLAKALMIREKYARLAYHRFPRTTAQYLAHQGESVPLEEGLPDFHPPPLPQEDPYCLDDAPPNLGYLVRMQGGVLFVYDNQTMLERQEPHSLPYPDLETYIVDMSHILALITDGPTKTYCHRRLNFLESKFSLHEMLNEMSEFKELKSNPHRDFYNVRKVDTHIHAAACMNQKHLLRFIKYTYQTEPDRTVAEKLGRKITLRQVFDSLHMDPYDLTVDSLDVHAGRQTFHGFDKFNSKYNPVGASELRDLYLKTENYLGGEYFARMVKEVARELEDSKYQYSEPRLSIYGRSPKEWSSLARWFIQHKVYSPNMRWIIQVPRIYDIFRSKKLLPSFGKMLENIFLPLFQATINPQDHRELHLFLKYVTGFDSVDDESKHSDHMFSDKSPSPDLWTSEQNPPYSYYLYYMYANIMVLNNLRRERGLSTFLFRPHCGEAGSITHLVSAFLTADNISHGLLLKKSPVLQYLYYLAQIPIAMSPLSNNSLFLEYSKNPLREFLHKGLHVSLSTDDPMQFHYTKEALMEEYAIAAQVWKLSTCDLCEIARNSVLQSGLSHQEKQKFLGQNYYKEGPEGNDIRKTNVAQIRMAFRYETLCNELSFLSDAMKSEEITALAD", "length": 765 }, "evidence": [ { "id": "F1NG97", "url": "https://omabrowser.org/oma/group/F1NG97/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O80452-1", "protein_name": "AMP deaminase", "gene_name": "AMPD", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MEPNIYQLALAALFGASFVAVSGFFMHFKALNLVLERGKERKENPDGDEPQNPTLVRRRSQVRRKVNDQYGRSPASLPDATPFTDGGGGGGGDTGRSNGHVYVDEIPPGLPRLHTPSEGRASVHGASSIRKTGSFVRPISPKSPVASASAFESVEESDDDDNLTNSEGLDASYLQANGDNEMPADANEEQISMAASSMIRSHSVSGDLHGVQPDPIAADILRKEPEQETFVRLNVPLEVPTSDEVEAYKCLQECLELRKRYVFQETVAPWEKEVISDPSTPKPNTEPFAHYPQGKSDHCFEMQDGVVHVFANKDAKEDLFPVADATAFFTDLHHVLKVIAAGNIRTLCHRRLVLLEQKFNLHLMLNADKEFLAQKSAPHRDFYNVRKVDTHVHHSACMNQKHLLRFIKSKLRKEPDEVVIFRDGTYLTLREVFESLDLTGYDLNVDLLDVHADKSTFHRFDKFNLKYNPCGQSRLREIFLKQDNLIQGRFLGEITKQVFSDLEASKYQMAEYRISIYGRKMSEWDQLASWIVNNDLYSENVVWLIQLPRLYNIYKDMGIVTSFQNILDNIFIPLFEATVDPDSHPQLHVFLKQVVGFDLVDDESKPERRPTKHMPTPAQWTNAFNPAFSYYVYYCYANLYVLNKLRESKGMTTITLRPHSGEAGDIDHLAATFLTCHSIAHGINLRKSPVLQYLYYLAQIGLAMSPLSNNSLFLDYHRNPFPVFFLRGLNVSLSTDDPLQIHLTKEPLVEEYSIAASVWKLSACDLCEIARNSVYQSGFSHALKSHWIGKDYYKRGPDGNDIHKTNVPHIRVEFRDTIWKEEMQQVYLGKAVISDEVVP", "length": 839 }, "evidence": [ { "id": "F1NG97", "url": "https://omabrowser.org/oma/group/F1NG97/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q01432-1", "protein_name": "AMP deaminase 3", "gene_name": "AMPD3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPRQFPKLNISEVDEQVRLLAEKVFAKVLREEDSKDALSLFTVPEDCPIGQKEAKERELQKELAEQKSVETAKRKKSFKMIRSQSLSLQMPPQQDWKGPPAASPAMSPTTPVVTGATSLPTPAPYAMPEFQRVTISGDYCAGITLEDYEQAAKSLAKALMIREKYARLAYHRFPRITSQYLGHPRADTAPPEEGLPDFHPPPLPQEDPYCLDDAPPNLDYLVHMQGGILFVYDNKKMLEHQEPHSLPYPDLETYTVDMSHILALITDGPTKTYCHRRLNFLESKFSLHEMLNEMSEFKELKSNPHRDFYNVRKVDTHIHAAACMNQKHLLRFIKHTYQTEPDRTVAEKRGRKITLRQVFDGLHMDPYDLTVDSLDVHAGRQTFHRFDKFNSKYNPVGASELRDLYLKTENYLGGEYFARMVKEVARELEESKYQYSEPRLSIYGRSPEEWPNLAYWFIQHKVYSPNMRWIIQVPRIYDIFRSKKLLPNFGKMLENIFLPLFKATINPQDHRELHLFLKYVTGFDSVDDESKHSDHMFSDKSPNPDVWTSEQNPPYSYYLYYMYANIMVLNNLRRERGLSTFLFRPHCGEAGSITHLVSAFLTADNISHGLLLKKSPVLQYLYYLAQIPIAMSPLSNNSLFLEYSKNPLREFLHKGLHVSLSTDDPMQFHYTKEALMEEYAIAAQVWKLSTCDLCEIARNSVLQSGLSHQEKQKFLGQNYYKEGPEGNDIRKTNVAQIRMAFRYETLCNELSFLSDAMKSEEITALTN", "length": 767 }, "evidence": [ { "id": "F1NG97", "url": "https://omabrowser.org/oma/group/F1NG97/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "AMP metabolic process", "id": "GO:0046033", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046033", "evidence": [ { "database": "UniProtKB", "id": "F1NG97", "url": "https://www.uniprot.org/uniprotkb/F1NG97" } ], "pmid": "" }, { "name": "energy homeostasis", "id": "GO:0097009", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097009", "evidence": [ { "database": "UniProtKB", "id": "F1NG97", "url": "https://www.uniprot.org/uniprotkb/F1NG97" } ], "pmid": "" }, { "name": "IMP biosynthetic process", "id": "GO:0006188", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006188", "evidence": [ { "database": "UniProtKB", "id": "F1NG97", "url": "https://www.uniprot.org/uniprotkb/F1NG97" } ], "pmid": "" }, { "name": "IMP salvage", "id": "GO:0032264", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032264", "evidence": [ { "database": "UniProtKB", "id": "F1NG97", "url": "https://www.uniprot.org/uniprotkb/F1NG97" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F1NG97", "url": "https://www.uniprot.org/uniprotkb/F1NG97" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "F1NG97", "url": "https://www.uniprot.org/uniprotkb/F1NG97" } ], "pmid": "" }, { "name": "AMP deaminase activity", "id": "GO:0003876", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003876", "evidence": [ { "database": "UniProtKB", "id": "F1NG97", "url": "https://www.uniprot.org/uniprotkb/F1NG97" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 603, "end_pos": 605, "annotation": "n_glycosylation_sequon" }, { "start_pos": 634, "end_pos": 636, "annotation": "n_glycosylation_sequon" }, { "start_pos": 9, "end_pos": 11, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "14777", "name": "", "equation": "AMP + H2O + H(+) = IMP + NH4(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P81073-1", "F1NG97-1", "A0A8V1ADW8-1", "A0A8V1A5I9-1" ], "evidence": [ { "id": "14777", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/14777" } ] }, { "id": "R-GGA-6798748", "name": "Exocytosis of secretory granule lumen proteins", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "extracellular region, secretory granule lumen", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A1D5PAA8-1", "A0A8V0X7U8-1", "A0A1D5PLH7-1", "A0A8V0XGV3-1", "A0A8V0XQ57-1", "A0A8V1AAF2-1", "A0A8V1ADZ5-1", "A0A8V1AIR0-1", "O57535-1", "Q90835-1", "A0A8V0ZIP8-1", "A0A8V0ZPK4-1", "A0A8V0ZQ64-1", "A0A8V0ZR27-1", "A0A8V0ZWJ4-1", "A0A8V0YHC8-1", "A0A8V0ZFP5-1", "A0A8V0ZG96-1", "A0A8V0ZTG8-1", "A0A8V0ZVL2-1", "A0A8V0Z0N7-1", "A0A8V0Z3A2-1", "F1NG97-1", "A0A8V0ZAK2-1", "A0A8V0ZG12-1", "A0A1D5PIQ5-1", "Q02977-1", "A0A8V0XXA9-1", "A0A8V0YAA4-1", "A0A8V0Y5M6-1", "A0A8V0YBU4-1", "A0A8V0YHT7-1" ], "evidence": [ { "id": "R-GGA-6798748", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6798748" } ] }, { "id": "R-GGA-6800434", "name": "Exocytosis of ficolin-rich granule lumen proteins", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "extracellular region, ficolin-1-rich granule lumen", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A1D5PAA8-1", "A0A8V0X7U8-1", "A0A1D5PLH7-1", "A0A8V0XGV3-1", "A0A8V1AAF2-1", "A0A8V1ADZ5-1", "A0A8V1AIR0-1", "F1NI04-1", "A0A1D5PSE5-1", "A0A8V0XAS9-1", "O57535-1", "P08267-1", "Q90835-1", "A0A1L1RSD2-1", "R4GH41-1", "A0A8V0Y6Q3-1", "A0A8V1AMW1-1", "A0A8V0ZPK4-1", "A0A8V0ZQ64-1", "A0A8V0ZR27-1", "A0A8V0ZWJ4-1", "F1NN63-1", "A0A8V1A3K8-1", "A0A8V1A4Q4-1", "A0A8V0YHC8-1", "A0A8V0YXL9-1", "A0A8V0ZFP5-1", "A0A8V0ZG96-1", "A0A8V0ZTG8-1", "A0A8V0ZVL2-1", "A0A8V0Z0N7-1", "A0A8V0Z0Z6-1", "A0A8V0Z3A2-1", "F1NG97-1", "A0A8V0ZAK2-1", "A0A8V0ZG12-1", "A0A1D5PIQ5-1", "Q05744-1", "A0A8V0XX04-1", "A0A8V0XXA9-1", "A0A8V0YAA4-1", "A0A8V0Y4H1-1", "A0A8V0Y5M6-1", "A0A8V0YDR9-1", "A0A8V0YHT7-1" ], "evidence": [ { "id": "R-GGA-6800434", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6800434" } ] }, { "id": "R-GGA-76590", "name": "AMP + H2O => IMP + NH4+ (AMPD)", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V1ADW8-1", "A0A8V1A5I9-1", "F1NG97-1" ], "evidence": [ { "id": "R-GGA-76590", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-76590" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A1D5PAA8", "gene_name": "GYG1", "activity": [ { "ec_number": "2.4.1.186", "activity": "[1,4-alpha-D-glucosyl](n)-L-tyrosyl-[glycogenin] + UDP-alpha-D-glucose = [1,4-alpha-D-glucosyl](n+1)-L-tyrosyl-[glycogenin] + UDP + H(+).", "evidence": [ { "id": "A0A1D5PAA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PAA8" } ] }, { "ec_number": "2.4.1.186", "activity": "", "evidence": [ { "id": "A0A1D5PAA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PAA8" } ] } ] }, { "uniprot_ac": "A0A1D5PIQ5", "gene_name": "MAPK14", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PIQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PIQ5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A1D5PIQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PIQ5" } ] } ] }, { "uniprot_ac": "A0A1D5PLH7", "gene_name": "PRDX4", "activity": [ { "ec_number": "1.11.1.24", "activity": "a hydroperoxide + [thioredoxin]-dithiol = an alcohol + [thioredoxin]-disulfide + H2O.", "evidence": [ { "id": "A0A1D5PLH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLH7" } ] }, { "ec_number": "1.11.1.24", "activity": "", "evidence": [ { "id": "A0A1D5PLH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLH7" } ] } ] }, { "uniprot_ac": "A0A1D5PSE5", "gene_name": "ACLY", "activity": [ { "ec_number": "2.3.3.8", "activity": "oxaloacetate + acetyl-CoA + ADP + phosphate = citrate + ATP + CoA.", "evidence": [ { "id": "A0A1D5PSE5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PSE5" } ] }, { "ec_number": "2.3.3.8", "activity": "", "evidence": [ { "id": "A0A1D5PSE5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PSE5" } ] } ] }, { "uniprot_ac": "A0A1L1RSD2", "gene_name": "GUSB", "activity": [ { "ec_number": "3.2.1.31", "activity": "a beta-D-glucuronoside + H2O = D-glucuronate + an alcohol.", "evidence": [ { "id": "A0A1L1RSD2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RSD2" } ] }, { "ec_number": "3.2.1.31", "activity": "", "evidence": [ { "id": "A0A1L1RSD2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RSD2" } ] } ] }, { "uniprot_ac": "A0A8V0X7U8", "gene_name": "ALDOA", "activity": [ { "ec_number": "4.1.2.13", "activity": "beta-D-fructose 1,6-bisphosphate = D-glyceraldehyde 3-phosphate + dihydroxyacetone phosphate.", "evidence": [ { "id": "A0A8V0X7U8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X7U8" } ] }, { "ec_number": "4.1.2.13", "activity": "", "evidence": [ { "id": "A0A8V0X7U8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X7U8" } ] } ] }, { "uniprot_ac": "A0A8V0XAS9", "gene_name": "CAPN1", "activity": [ { "ec_number": "3.4.22.52", "activity": "Broad endopeptidase specificity.", "evidence": [ { "id": "A0A8V0XAS9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XAS9" } ] }, { "ec_number": "3.4.22.52", "activity": "", "evidence": [ { "id": "A0A8V0XAS9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XAS9" } ] } ] }, { "uniprot_ac": "A0A8V0XGV3", "gene_name": "DDX3X", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XGV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XGV3" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0XGV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XGV3" } ] } ] }, { "uniprot_ac": "A0A8V0XQ57", "gene_name": "APRT", "activity": [ { "ec_number": "2.4.2.7", "activity": "AMP + diphosphate = 5-phospho-alpha-D-ribose 1-diphosphate + adenine.", "evidence": [ { "id": "A0A8V0XQ57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ57" } ] }, { "ec_number": "2.4.2.7", "activity": "", "evidence": [ { "id": "A0A8V0XQ57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ57" } ] } ] }, { "uniprot_ac": "A0A8V0XX04", "gene_name": "QPCT", "activity": [ { "ec_number": "2.3.2.5", "activity": "N-terminal L-glutaminyl-[peptide] = N-terminal 5-oxo-L-prolyl-[peptide] + NH4(+).", "evidence": [ { "id": "A0A8V0XX04", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XX04" } ] }, { "ec_number": "2.3.2.5", "activity": "", "evidence": [ { "id": "A0A8V0XX04", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XX04" } ] } ] }, { "uniprot_ac": "A0A8V0XXA9", "gene_name": "GPI", "activity": [ { "ec_number": "5.3.1.9", "activity": "alpha-D-fructose 6-phosphate = beta-D-fructose 6-phosphate.", "evidence": [ { "id": "A0A8V0XXA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XXA9" } ] }, { "ec_number": "5.3.1.9", "activity": "", "evidence": [ { "id": "A0A8V0XXA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XXA9" } ] } ] }, { "uniprot_ac": "A0A8V0Y4H1", "gene_name": "CTSB", "activity": [ { "ec_number": "3.4.22.1", "activity": "Hydrolysis of proteins with broad specificity for peptide bonds. Preferentially cleaves -Arg-Arg-|-Xaa bonds in small molecule substrates (thus differing from cathepsin L). In addition to being an endopeptidase, shows peptidyl-dipeptidase activity, liberating C-terminal dipeptides.", "evidence": [ { "id": "A0A8V0Y4H1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y4H1" } ] }, { "ec_number": "3.4.22.1", "activity": "", "evidence": [ { "id": "A0A8V0Y4H1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y4H1" } ] } ] }, { "uniprot_ac": "A0A8V0Y5M6", "gene_name": "HK3", "activity": [ { "ec_number": "2.7.1.1", "activity": "D-fructose + ATP = D-fructose 6-phosphate + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y5M6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5M6" } ] }, { "ec_number": "2.7.1.1", "activity": "", "evidence": [ { "id": "A0A8V0Y5M6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5M6" } ] } ] }, { "uniprot_ac": "A0A8V0Y6Q3", "gene_name": "LTA4H", "activity": [ { "ec_number": "3.3.2.6", "activity": "leukotriene A4 + H2O = leukotriene B4.", "evidence": [ { "id": "A0A8V0Y6Q3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y6Q3" } ] }, { "ec_number": "3.3.2.6", "activity": "", "evidence": [ { "id": "A0A8V0Y6Q3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y6Q3" } ] } ] }, { "uniprot_ac": "A0A8V0YAA4", "gene_name": "XRCC6", "activity": [ { "ec_number": "4.2.99.18", "activity": "2'-deoxyribonucleotide-(2'-deoxyribose 5'-phosphate)-2'-deoxyribonucleotide-DNA = a 3'-end 2'-deoxyribonucleotide-(2,3-dehydro-2,3-deoxyribose 5'-phosphate)-DNA + a 5'-end 5'-phospho-2'-deoxyribonucleoside-DNA + H(+).", "evidence": [ { "id": "A0A8V0YAA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAA4" } ] }, { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YAA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAA4" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "A0A8V0YAA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAA4" } ] }, { "ec_number": "4.2.99.18", "activity": "", "evidence": [ { "id": "A0A8V0YAA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAA4" } ] } ] }, { "uniprot_ac": "A0A8V0YBU4", "gene_name": "PDXK", "activity": [ { "ec_number": "2.7.1.35", "activity": "pyridoxine + ATP = pyridoxine 5'-phosphate + ADP + H(+).", "evidence": [ { "id": "A0A8V0YBU4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBU4" } ] }, { "ec_number": "2.7.1.35", "activity": "", "evidence": [ { "id": "A0A8V0YBU4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBU4" } ] } ] }, { "uniprot_ac": "A0A8V0YDR9", "gene_name": "KCMF1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YDR9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDR9" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0YDR9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDR9" } ] } ] }, { "uniprot_ac": "A0A8V0YHC8", "gene_name": "VCP", "activity": [ { "ec_number": "3.6.4.6", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YHC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHC8" } ] }, { "ec_number": "3.6.4.6", "activity": "", "evidence": [ { "id": "A0A8V0YHC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHC8" } ] } ] }, { "uniprot_ac": "A0A8V0YHT7", "gene_name": "DERA", "activity": [ { "ec_number": "4.1.2.4", "activity": "2-deoxy-D-ribose 5-phosphate = D-glyceraldehyde 3-phosphate + acetaldehyde.", "evidence": [ { "id": "A0A8V0YHT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHT7" } ] }, { "ec_number": "4.1.2.4", "activity": "", "evidence": [ { "id": "A0A8V0YHT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHT7" } ] } ] }, { "uniprot_ac": "A0A8V0YXL9", "gene_name": "MMP9", "activity": [ { "ec_number": "3.4.24.35", "activity": "Cleavage of gelatin types I and V and collagen types IV and V.", "evidence": [ { "id": "A0A8V0YXL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXL9" } ] }, { "ec_number": "3.4.24.35", "activity": "", "evidence": [ { "id": "A0A8V0YXL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXL9" } ] } ] }, { "uniprot_ac": "A0A8V0Z0N7", "gene_name": "PPIA", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "A0A8V0Z0N7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z0N7" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "A0A8V0Z0N7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z0N7" } ] } ] }, { "uniprot_ac": "A0A8V0Z0Z6", "gene_name": "GLB1", "activity": [ { "ec_number": "3.2.1.23", "activity": "Hydrolysis of terminal non-reducing beta-D-galactose residues in beta-D-galactosides.", "evidence": [ { "id": "A0A8V0Z0Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z0Z6" } ] }, { "ec_number": "3.2.1.23", "activity": "", "evidence": [ { "id": "A0A8V0Z0Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z0Z6" } ] } ] }, { "uniprot_ac": "A0A8V0Z3A2", "gene_name": "PPIE", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "A0A8V0Z3A2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3A2" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "A0A8V0Z3A2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3A2" } ] } ] }, { "uniprot_ac": "A0A8V0ZAK2", "gene_name": "PYGL", "activity": [ { "ec_number": "2.4.1.1", "activity": "[(1->4)-alpha-D-glucosyl](n) + phosphate = [(1->4)-alpha-D-glucosyl](n-1) + alpha-D-glucose 1-phosphate.", "evidence": [ { "id": "A0A8V0ZAK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAK2" } ] }, { "ec_number": "2.4.1.1", "activity": "", "evidence": [ { "id": "A0A8V0ZAK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAK2" } ] } ] }, { "uniprot_ac": "A0A8V0ZFP5", "gene_name": "PGAM1", "activity": [ { "ec_number": "5.4.2.11", "activity": "(2R)-2-phosphoglycerate = (2R)-3-phosphoglycerate.", "evidence": [ { "id": "A0A8V0ZFP5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFP5" } ] }, { "ec_number": "5.4.2.4", "activity": "(2R)-3-phospho-glyceroyl phosphate = (2R)-2,3-bisphosphoglycerate + H(+).", "evidence": [ { "id": "A0A8V0ZFP5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFP5" } ] }, { "ec_number": "5.4.2.4", "activity": "", "evidence": [ { "id": "A0A8V0ZFP5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFP5" } ] }, { "ec_number": "5.4.2.11", "activity": "", "evidence": [ { "id": "A0A8V0ZFP5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFP5" } ] } ] }, { "uniprot_ac": "A0A8V0ZG12", "gene_name": "CDA", "activity": [ { "ec_number": "3.5.4.5", "activity": "cytidine + H2O + H(+) = uridine + NH4(+).", "evidence": [ { "id": "A0A8V0ZG12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG12" } ] }, { "ec_number": "3.5.4.5", "activity": "", "evidence": [ { "id": "A0A8V0ZG12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG12" } ] } ] }, { "uniprot_ac": "A0A8V0ZG96", "gene_name": "PKLR", "activity": [ { "ec_number": "2.7.1.40", "activity": "ITP + pyruvate = IDP + phosphoenolpyruvate + H(+).", "evidence": [ { "id": "A0A8V0ZG96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG96" } ] }, { "ec_number": "2.7.1.40", "activity": "", "evidence": [ { "id": "A0A8V0ZG96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG96" } ] } ] }, { "uniprot_ac": "A0A8V0ZIP8", "gene_name": "XRCC5", "activity": [ { "ec_number": "4.2.99.18", "activity": "2'-deoxyribonucleotide-(2'-deoxyribose 5'-phosphate)-2'-deoxyribonucleotide-DNA = a 3'-end 2'-deoxyribonucleotide-(2,3-dehydro-2,3-deoxyribose 5'-phosphate)-DNA + a 5'-end 5'-phospho-2'-deoxyribonucleoside-DNA + H(+).", "evidence": [ { "id": "A0A8V0ZIP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIP8" } ] }, { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0ZIP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIP8" } ] }, { "ec_number": "4.2.99.18", "activity": "", "evidence": [ { "id": "A0A8V0ZIP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIP8" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "A0A8V0ZIP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIP8" } ] } ] }, { "uniprot_ac": "A0A8V0ZPK4", "gene_name": "IDH1", "activity": [ { "ec_number": "1.1.1.42", "activity": "D-threo-isocitrate + NADP(+) = 2-oxoglutarate + CO2 + NADPH.", "evidence": [ { "id": "A0A8V0ZPK4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPK4" } ] }, { "ec_number": "1.1.1.42", "activity": "", "evidence": [ { "id": "A0A8V0ZPK4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPK4" } ] } ] }, { "uniprot_ac": "A0A8V0ZQ64", "gene_name": "AGL", "activity": [ { "ec_number": "2.4.1.25", "activity": "Transfers a segment of a (1->4)-alpha-D-glucan to a new position in an acceptor, which may be glucose or a (1->4)-alpha-D-glucan.", "evidence": [ { "id": "A0A8V0ZQ64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ64" } ] }, { "ec_number": "3.2.1.33", "activity": "Hydrolysis of (1->6)-alpha-D-glucosidic branch linkages in glycogen phosphorylase limit dextrin.", "evidence": [ { "id": "A0A8V0ZQ64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ64" } ] }, { "ec_number": "2.4.1.25", "activity": "", "evidence": [ { "id": "A0A8V0ZQ64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ64" } ] }, { "ec_number": "3.2.1.33", "activity": "", "evidence": [ { "id": "A0A8V0ZQ64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ64" } ] } ] }, { "uniprot_ac": "A0A8V0ZR27", "gene_name": "PAFAH1B2", "activity": [ { "ec_number": "3.1.1.47", "activity": "a 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0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1NWY5-1", "uniprot_ac": "F1NWY5", "uniprot_id": "F1NWY5_CHICK", "mass": { "chemical_mass": 50072.0, "monoisotopic_mass": 50072.0 }, "refseq": { "ac": "NP_001026301", "name": "neuropeptide Y receptor type 5", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026301" }, "gene_names": [ { "name": "NPY5R", "type": "recommended", "evidence": [ { "id": "F1NWY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NWY5" } ] }, { "name": "NPY5R", "type": "synonym", "evidence": [ { "id": "NP_001026301", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026301" } ] }, { "name": "NPY5", "type": "synonym", "evidence": [ { "id": "NP_001026301", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026301" } ] }, { "name": "Y5", "type": "synonym", "evidence": [ { "id": "NP_001026301", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026301" } ] } ], "protein_names": [ { "name": "Neuropeptide Y receptor type 5", "type": "recommended", "evidence": [ { "id": "F1NWY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NWY5/entry#names_and_taxonomy" } ] }, { "name": "G-protein coupled receptor", "type": "synonym", "evidence": [ { "id": "NP_001026301", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026301" } ] }, { "name": "NPY-Y5 receptor", "type": "synonym", "evidence": [ { "id": "F1NWY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NWY5/entry#names_and_taxonomy" } ] }, { "name": "neuropeptide Y receptor type 5", "type": "synonym", "evidence": [ { "id": "NP_001026301", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026301" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: SRR13267649.206236.1, ERR2368565.299749.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992482 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000071.1. On or before Dec 8, 2021 this sequence version replaced XP_040554803.1, NP_001026301.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001026301", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026301" } ] }, { "annotation": "Receptor for neuropeptide Y and peptide YY. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity. Seems to be associated with food intake. Could be involved in feeding disorders.", "evidence": [ { "database": "UniProtKB", "id": "F1NWY5", "url": "https://www.uniprot.org/uniprotkb/F1NWY5#function" }, { "database": "UniProtKB", "id": "ARBA00024704", "url": "https://www.uniprot.org/uniprotkb/ARBA00024704#function" }, { "database": "UniProtKB", "id": "A0A8V0XZF5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XZF5#function" } ] }, { "annotation": "The results of the present study indicated that somatostatin-induced hyperphagia may be modulated by the NPY1 receptor (not the NPY2 and NPY5 receptors) in neonatal chicks.", "evidence": [ { "database": "RefSeq", "id": "NP_001026301", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026301" }, { "database": "PubMed", "id": "30444128", "url": "https://glygen.org/publication/PubMed/30444128" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NWY5", "url": "https://www.uniprot.org/uniprotkb/F1NWY5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "NPY5R", "url": "https://www.uniprot.org/uniprotkb/F1NWY5", "locus": { "chromosome": "4", "start_pos": 22842631, "end_pos": 22832597, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010007932", "url": "https://www.ensembl.org/id/ENSGALG00010007932" } ] } } ], "crossref": [ { "id": "ENSGALG00000009499", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000009499", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd15398", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15398", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "422419", "url": "https://www.ncbi.nlm.nih.gov/gene/422419", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000393", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000393", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000611", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000611", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:422419", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422419", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "RHHQDTH", "url": "https://omabrowser.org/oma/group/RHHQDTH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XZF5", "url": "https://www.orthodb.org/?gene=A0A8V0XZF5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NWY5", "url": "https://www.orthodb.org/?gene=F1NWY5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24235", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24235", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24235:SF10", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24235:SF10", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00001", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00001", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-375276", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-375276", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-418594", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-418594", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001026301", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026301", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0XZF5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XZF5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XZF5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XZF5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NWY5", "url": "https://www.uniprot.org/uniprotkb/F1NWY5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NWY5-1", "url": "https://www.uniprot.org/uniprotkb/F1NWY5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDLGFKDYTNRTPTKNTSATTKNFSAWEDYKSSVDDIQYFLIGLYTLISLAGFVGNLLVLTALTKRKQKTIINILIGNLAFSDILVVLFCSPFTLTSVLLDRWMFGTVMCHIMPFLQCTSVLVSTLMLISIAAVRYRMVKYPLSSNLTAKHGYFLIVIIWAVGCAICSPLPVFHKIVDLHKTLNLEALENRLLCIESWPSDSYRIAFTISLLLMQYILPLVCLTASHTSVCRSVGSRLSSKEGKFQENEMINLTLHPSKSAGTEAQPSNHTSWSCALVRKHHRRYSKKTSTVMPAILRQQQDADFRDLPETSGTEKSQLSSSSKFIPGVPICFEMKPEENTEIQDMITVSQSIIRIKTRSRRVFCRLTVLILVFGFSWMPLHLFHIVTDFNATLISNRHFKLVYCICHLLGMMSCCLNPILYGFLNNSIKADLMSLIPCCQIL", "length": 443, "header": "tr|F1NWY5-1|F1NWY5_CHICK Isoform 1 of Neuropeptide Y receptor type 5 OS=Gallus gallus OX=9031 GN=NPY5R PE=3 SV=2 CANONICAL=F1NWY5-1" }, "isoforms": [ { "isoform_ac": "A0A8V0XZF5-1", "url": "https://www.uniprot.org/uniprotkb/F1NWY5/entry#A0A8V0XZF5-1", "sequence": { "sequence": "MQSKIIFLYGLLYTSIIFPSVANRCLSCSKQDYKMDLGFKDYTNRTPTKNTSATTKNFSAWEDYKSSVDDIQYFLIGLYTLISLAGFVGNLLVLTALTKRKQKTIINILIGNLAFSDILVVLFCSPFTLTSVLLDRWMFGTVMCHIMPFLQCTSVLVSTLMLISIAAVRYRMVKYPLSSNLTAKHGYFLIVIIWAVGCAICSPLPVFHKIVDLHKTLNLEALENRLLCIESWPSDSYRIAFTISLLLMQYILPLVCLTASHTSVCRSVGSRLSSKEGKFQENEMINLTLHPSKSAGTEAQPSNHTSWSCALVRKHHRRYSKKTSTVMPAILRQQQDADFRDLPETSGTEKSQLSSSSKFIPGVPICFEMKPEENTEIQDMITVSQSIIRIKTRSRRVFCRLTVLILVFGFSWMPLHLFHIVTDFNATLISNRHFKLVYCICHLLGMMSCCLNPILYGFLNNSIKADLMSLIPCCQIL", "length": 477, "header": "tr|A0A8V0XZF5-1|A0A8V0XZF5_CHICK Computationally mapped isoform of Neuropeptide Y receptor type 5 OS=Gallus gallus OX=9031 GN=NPY5R PE=3 SV=1 CANONICAL=F1NWY5-1" }, "locus": { "chromosome": "4", "start_pos": 22841348, "end_pos": 22839918, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010018908.1", "url": "https://www.ensembl.org/id/ENSGALT00010018908.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010010458.1", "url": "https://www.ensembl.org/id/ENSGALP00010010458.1" } ] } }, { "isoform_ac": "F1NWY5-1", "url": "https://www.uniprot.org/uniprotkb/F1NWY5/entry#F1NWY5-1", "sequence": { "sequence": "MDLGFKDYTNRTPTKNTSATTKNFSAWEDYKSSVDDIQYFLIGLYTLISLAGFVGNLLVLTALTKRKQKTIINILIGNLAFSDILVVLFCSPFTLTSVLLDRWMFGTVMCHIMPFLQCTSVLVSTLMLISIAAVRYRMVKYPLSSNLTAKHGYFLIVIIWAVGCAICSPLPVFHKIVDLHKTLNLEALENRLLCIESWPSDSYRIAFTISLLLMQYILPLVCLTASHTSVCRSVGSRLSSKEGKFQENEMINLTLHPSKSAGTEAQPSNHTSWSCALVRKHHRRYSKKTSTVMPAILRQQQDADFRDLPETSGTEKSQLSSSSKFIPGVPICFEMKPEENTEIQDMITVSQSIIRIKTRSRRVFCRLTVLILVFGFSWMPLHLFHIVTDFNATLISNRHFKLVYCICHLLGMMSCCLNPILYGFLNNSIKADLMSLIPCCQIL", "length": 443, "header": "tr|F1NWY5-1|F1NWY5_CHICK Isoform 1 of Neuropeptide Y receptor type 5 OS=Gallus gallus OX=9031 GN=NPY5R PE=3 SV=2 CANONICAL=F1NWY5-1" }, "locus": { "chromosome": "4", "start_pos": 22841348, "end_pos": 22840020, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010018914.1", "url": "https://www.ensembl.org/id/ENSGALT00010018914.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010010464.1", "url": "https://www.ensembl.org/id/ENSGALP00010010464.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Interaction of neuropeptide Y receptors (NPY1, NPY2 and NPY5) with somatostatin on somatostatin-induced feeding behaviour in neonatal chicken.", "journal": "British poultry science", "date": "2019-02", "authors": "Yousefvand S, Hamidi F, Zendehdel M, Parham A", "evidence": [ { "database": "RefSeq", "id": "NP_001026301", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026301" } ], "reference": [ { "type": "PubMed", "id": "30444128", "url": "https://glygen.org/publication/PubMed/30444128" } ] } ], "pathway": [ { "id": "gga:422419", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422419", "resource": "KEGG Pathway" }, { "id": "R-GGA-375276", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-375276", "resource": "Reactome", "description": "Peptide ligand-binding receptors" }, { "id": "R-GGA-418594", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-418594", "resource": "Reactome", "description": "G alpha (i) signalling events" } ], "orthologs": [ { "uniprot_canonical_ac": "G3I6N8-1", "protein_name": "Neuropeptide Y receptor type 5", "gene_name": "Npy5r", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MDFELEEHVNKTIVAENNTAATRNAAYPVWDDYRSTENNTAAARNAAFPVWDDYRGSVDDLQYFLIGLYTFVSLLGFMGNLLILMAVMKKRNQKTTVNFLIGNLAFSDILVVLFCSPSTLTSVLLDQWMFGKAMCHVMPFLQCVSVLVSTLILISIAIVRYHMIKHPISNNLTANHGYFLIATVWTLGFAICSPLPVFHSLVELKETFGSALLSSKYLCVESWPSDSYRIAFTISLLLVQYILPLVCLTVSHTSVCRSISCGLSHKENRLEENEMINLTLHPSKKSGNQANPQSRQKWTYSFIRKHRRRYSKKTACVLPAPAGPSKEIHPTVPEKLGSVRSQFSSSSKVIPGVPTCFEVKPEGNSDAHEMRVKRSITRIKKRSRSVFYRLTILILVFAVSWMPLHLFHVVTDFNDNLISNRHFKLVYCICHLLGMMSCCLNPILYGFLNNGIKADLRALIHCLHMS", "length": 466 }, "evidence": [ { "id": "F1NWY5", "url": "https://omabrowser.org/oma/group/F1NWY5/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "O70342-1", "protein_name": "Neuropeptide Y receptor type 5", "gene_name": "Npy5r", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEVKLEEHFNKTFVTENNTAASQNTASPAWEDYRGTENNTSAARNTAFPVWEDYRGSVDDLQYFLIGLYTFVSLLGFMGNLLILMAVMKKRNQKTTVNFLIGNLAFSDILVVLFCSPFTLTSVLLDQWMFGKAMCHIMPFLQCVSVLVSTLILISIAIVRYHMIKHPISNNLTANHGYFLIATVWTLGFAICSPLPVFHSLVELKETFGSALLSSKYLCVESWPSDSYRIAFTISLLLVQYILPLVCLTVSHTSVCRSISCGLSHKENRLEENEMINLTLHPSKKSRDQAKPPSTQKWSYSFIRKHRRRYSKKTACVLPAPAGPSQEKHLTVPENPGSVRSQLSPSSKVIPGVPICFEVKPEESSDAQEMRVKRSLTRIKKRSRSVFYRLTILILVFAVSWMPLHVFHVVTDFNDNLISNRHFKLVYCICHLLGMMSCCLNPILYGFLNNGIKADLRALIHCLHMS", "length": 466 }, "evidence": [ { "id": "F1NWY5", "url": "https://omabrowser.org/oma/group/F1NWY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "O97969-1", "protein_name": "Neuropeptide Y receptor type 5", "gene_name": "NPY5R", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGSEIPDYYNKTLASENNTVATRNSGFPVWEDYKGSVDDLQYFLIGLYTFVSLLGFMGNLLILMAVMRKRNQKTTVNFLIGNLAFSDILVVLFCSPFTLTSVLLDQWMFGKVMCHIMPFLQCVTVLVSTLILISIAIVRYHMIKHPVSNNLTANHGYFLIATVWTLGLAICSPLPVFHSLVELQESFGSAWLSSRYLCVESWPSDSYRIAFTISLLLVQYILPLVCLTVSHTSVCRTISCGLSSQDSKLEENEMINLTLQPAKRSGPQAKLSHHPKWTYSFIRRHRRRYSKKTACVRPAPAGPALESREGRPPGKVGSMQSQPPPSNKFMPGVPTCFEVKPEENSDVPEMRVSRSIMRLRKRSRSVFYRLTVLILVFAVSWMPLHLFHVVTDFNDNLISNRHFKLVYCICHLLGMMSCCLNPILYGFLNNGIKADLMSLIHCLHVS", "length": 446 }, "evidence": [ { "id": "F1NWY5", "url": "https://omabrowser.org/oma/group/F1NWY5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q15761-1", "protein_name": "Neuropeptide Y receptor type 5", "gene_name": "NPY5R", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDLELDEYYNKTLATENNTAATRNSDFPVWDDYKSSVDDLQYFLIGLYTFVSLLGFMGNLLILMALMKKRNQKTTVNFLIGNLAFSDILVVLFCSPFTLTSVLLDQWMFGKVMCHIMPFLQCVSVLVSTLILISIAIVRYHMIKHPISNNLTANHGYFLIATVWTLGFAICSPLPVFHSLVELQETFGSALLSSRYLCVESWPSDSYRIAFTISLLLVQYILPLVCLTVSHTSVCRSISCGLSNKENRLEENEMINLTLHPSKKSGPQVKLSGSHKWSYSFIKKHRRRYSKKTACVLPAPERPSQENHSRILPENFGSVRSQLSSSSKFIPGVPTCFEIKPEENSDVHELRVKRSVTRIKKRSRSVFYRLTILILVFAVSWMPLHLFHVVTDFNDNLISNRHFKLVYCICHLLGMMSCCLNPILYGFLNNGIKADLVSLIHCLHM", "length": 445 }, "evidence": [ { "id": "F1NWY5", "url": "https://omabrowser.org/oma/group/F1NWY5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q63634-1", "protein_name": "Neuropeptide Y receptor type 5", "gene_name": "Npy5r", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEFKLEEHFNKTFVTENNTAAARNAAFPAWEDYRGSVDDLQYFLIGLYTFVSLLGFMGNLLILMAVMKKRNQKTTVNFLIGNLAFSDILVVLFCSPFTLTSVLLDQWMFGKAMCHIMPFLQCVSVLVSTLILISIAIVRYHMIKHPISNNLTANHGYFLIATVWTLGFAICSPLPVFHSLVELKETFGSALLSSKYLCVESWPSDSYRIAFTISLLLVQYILPLVCLTVSHTSVCRSISCGLSHKENRLEENEMINLTLQPSKKSRNQAKTPSTQKWSYSFIRKHRRRYSKKTACVLPAPAGPSQGKHLAVPENPASVRSQLSPSSKVIPGVPICFEVKPEESSDAHEMRVKRSITRIKKRSRSVFYRLTILILVFAVSWMPLHVFHVVTDFNDNLISNRHFKLVYCICHLLGMMSCCLNPILYGFLNNGIKADLRALIHCLHMS", "length": 445 }, "evidence": [ { "id": "F1NWY5", "url": "https://omabrowser.org/oma/group/F1NWY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "GABA-ergic synapse", "id": "GO:0098982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098982", "evidence": [ { "database": "UniProtKB", "id": "F1NWY5", "url": "https://www.uniprot.org/uniprotkb/F1NWY5" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F1NWY5", "url": "https://www.uniprot.org/uniprotkb/F1NWY5" } ], "pmid": "" }, { "name": "neuron projection", "id": "GO:0043005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043005", "evidence": [ { "database": "UniProtKB", "id": "F1NWY5", "url": "https://www.uniprot.org/uniprotkb/F1NWY5" } ], "pmid": "" }, { "name": "presynapse", "id": "GO:0098793", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098793", "evidence": [ { "database": "UniProtKB", "id": "F1NWY5", "url": "https://www.uniprot.org/uniprotkb/F1NWY5" } ], "pmid": "" }, { "name": "9+0 non-motile cilium", "id": "GO:0097731", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097731", "evidence": [ { "database": "UniProtKB", "id": "F1NWY5", "url": "https://www.uniprot.org/uniprotkb/F1NWY5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "neuropeptide signaling pathway", "id": "GO:0007218", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007218", "evidence": [ { "database": "UniProtKB", "id": "F1NWY5", "url": "https://www.uniprot.org/uniprotkb/F1NWY5" } ], "pmid": "" }, { "name": "chemical synaptic transmission", "id": "GO:0007268", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007268", "evidence": [ { "database": "UniProtKB", "id": "F1NWY5", "url": "https://www.uniprot.org/uniprotkb/F1NWY5" } ], "pmid": "" }, { "name": "outflow tract morphogenesis", "id": "GO:0003151", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003151", "evidence": [ { "database": "UniProtKB", "id": "F1NWY5", "url": "https://www.uniprot.org/uniprotkb/F1NWY5" } ], "pmid": "" }, { "name": "cardiac left ventricle morphogenesis", "id": "GO:0003214", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003214", "evidence": [ { "database": "UniProtKB", "id": "F1NWY5", "url": "https://www.uniprot.org/uniprotkb/F1NWY5" } ], "pmid": "" }, { "name": "synaptic signaling via neuropeptide", "id": "GO:0099538", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099538", "evidence": [ { "database": "UniProtKB", "id": "F1NWY5", "url": "https://www.uniprot.org/uniprotkb/F1NWY5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "peptide YY receptor activity", "id": "GO:0001601", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001601", "evidence": [ { "database": "UniProtKB", "id": "F1NWY5", "url": "https://www.uniprot.org/uniprotkb/F1NWY5" } ], "pmid": "" }, { "name": "pancreatic polypeptide receptor activity", "id": "GO:0001602", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001602", "evidence": [ { "database": "UniProtKB", "id": "F1NWY5", "url": "https://www.uniprot.org/uniprotkb/F1NWY5" } ], "pmid": "" }, { "name": "neuropeptide Y receptor activity", "id": "GO:0004983", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004983", "evidence": [ { "database": "UniProtKB", "id": "F1NWY5", "url": "https://www.uniprot.org/uniprotkb/F1NWY5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 10, "end_pos": 12, "annotation": "n_glycosylation_sequon" }, { "start_pos": 146, "end_pos": 148, "annotation": "n_glycosylation_sequon" }, { "start_pos": 16, "end_pos": 18, "annotation": "n_glycosylation_sequon" }, { "start_pos": 23, "end_pos": 25, "annotation": "n_glycosylation_sequon" }, { "start_pos": 252, "end_pos": 254, "annotation": "n_glycosylation_sequon" }, { "start_pos": 269, "end_pos": 271, "annotation": "n_glycosylation_sequon" }, { "start_pos": 391, "end_pos": 393, "annotation": "n_glycosylation_sequon" }, { "start_pos": 426, "end_pos": 428, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1NWY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NWY5" }, { "id": "PS50262", 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"total": 4, "go_terms": [ { "name": "autophagosome membrane", "id": "GO:0000421", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000421", "evidence": [ { "database": "UniProtKB", "id": "F1P145", "url": "https://www.uniprot.org/uniprotkb/F1P145" } ], "pmid": "" }, { "name": "phagophore assembly site membrane", "id": "GO:0034045", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034045", "evidence": [ { "database": "UniProtKB", "id": "F1P145", "url": "https://www.uniprot.org/uniprotkb/F1P145" } ], "pmid": "" }, { "name": "Atg12-Atg5-Atg16 complex", "id": "GO:0034274", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034274", "evidence": [ { "database": "UniProtKB", "id": "F1P145", "url": "https://www.uniprot.org/uniprotkb/F1P145" } ], "pmid": "" }, { "name": "protein-containing complex", "id": "GO:0032991", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032991", "evidence": [ { "database": "UniProtKB", "id": "F1P145", "url": "https://www.uniprot.org/uniprotkb/F1P145" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "protein tag activity", "id": "GO:0031386", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031386", "evidence": [ { "database": "UniProtKB", "id": "F1P145", "url": "https://www.uniprot.org/uniprotkb/F1P145" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 111, "end_pos": 113, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 111, "end_pos": 113 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": 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"publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1NW95-1", "uniprot_ac": "F1NW95", "uniprot_id": "F1NW95_CHICK", "mass": { "chemical_mass": 16945.0, "monoisotopic_mass": 16945.0 }, "refseq": { "ac": "NP_001171687", "name": "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001171687" }, "gene_names": [ { "name": "NDUFA12", "type": "recommended", "evidence": [ { "id": "F1NW95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NW95" } ] }, { "name": "NDUFA12", "type": "synonym", "evidence": [ { "id": "NP_001171687", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001171687" } ] } ], "protein_names": [ { "name": "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12", "type": "recommended", "evidence": [ { "id": "F1NW95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NW95/entry#names_and_taxonomy" } ] }, { "name": "13kDa differentiation-associated protein", "type": "synonym", "evidence": [ { "id": "NP_001171687", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001171687" } ] }, { "name": "NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 12", "type": "synonym", "evidence": [ { "id": "NP_001171687", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001171687" } ] }, { "name": "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12", "type": "synonym", "evidence": [ { "id": "NP_001171687", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001171687" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: BU327954.1, BU259564.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: inferred from homology ##RefSeq-Attributes-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BU259564.1 and DR430374.1. On Nov 23, 2021 this sequence version replaced NP_001171687.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001171687", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001171687" } ] }, { "annotation": "Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Y6X8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y6X8#function" }, { "database": "UniProtKB", "id": "RU363103", "url": "https://www.uniprot.org/uniprotkb/RU363103#function" }, { "database": "UniProtKB", "id": "F1NW95", "url": "https://www.uniprot.org/uniprotkb/F1NW95#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NW95", "url": "https://www.uniprot.org/uniprotkb/F1NW95" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "NDUFA12", "url": "https://www.uniprot.org/uniprotkb/F1NW95", "locus": { "chromosome": "1", "start_pos": 45360098, "end_pos": 45367798, "strand": "+", "evidence": [ { "database": "Ensembl 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"Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001171687", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001171687", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Y6X8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y6X8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y6X8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y6X8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NW95", "url": "https://www.uniprot.org/uniprotkb/F1NW95", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NW95-1", "url": "https://www.uniprot.org/uniprotkb/F1NW95-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAEYVQVVKRAFKHLGGHGGVRGAILQLLRVNDLKTGTLVGVDKYGNKYYEDKRNFFGRHRWVVYTSEMNGKNTFWEVDGSMVPPEWHRWLHSMTDDPPTTHPPVARKFIWENHKFNLSGTPGQYVPYSTTRKKIQEWIPPTTASK", "length": 146, "header": "tr|F1NW95-1|F1NW95_CHICK Isoform 1 of NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 OS=Gallus gallus OX=9031 GN=NDUFA12 PE=1 SV=2 CANONICAL=F1NW95-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Y6X8-1", "url": "https://www.uniprot.org/uniprotkb/F1NW95/entry#A0A8V0Y6X8-1", "sequence": { "sequence": "MAEYVQVVKRAFKHLGGHGGVRGAILQLLRVNDLKTGTLVGVDKYGNKYYEDKRNFFGRHRWVVYTSEMNGKNTFWEVDGSMVPPEWQKFGGFTCLSIGSAALCLRKLLQPLPSCCCPPLLCISRLLLFRHRWLHSMTDDPPTTHPPVARKFIWENHKFNLSGTPGQYVPYSTTRKKIQEWIPPTTASK", "length": 189, "header": "tr|A0A8V0Y6X8-1|A0A8V0Y6X8_CHICK Computationally mapped isoform of NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 OS=Gallus gallus OX=9031 GN=NDUFA12 PE=1 SV=1 CANONICAL=F1NW95-1" }, "locus": { "chromosome": "1", "start_pos": 45367643, "end_pos": 45360290, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010023032.1", "url": "https://www.ensembl.org/id/ENSGALT00010023032.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010013325.1", "url": "https://www.ensembl.org/id/ENSGALP00010013325.1" } ] } }, { "isoform_ac": "F1NW95-1", "url": "https://www.uniprot.org/uniprotkb/F1NW95/entry#F1NW95-1", "sequence": { "sequence": "MAEYVQVVKRAFKHLGGHGGVRGAILQLLRVNDLKTGTLVGVDKYGNKYYEDKRNFFGRHRWVVYTSEMNGKNTFWEVDGSMVPPEWHRWLHSMTDDPPTTHPPVARKFIWENHKFNLSGTPGQYVPYSTTRKKIQEWIPPTTASK", "length": 146, "header": "tr|F1NW95-1|F1NW95_CHICK Isoform 1 of NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 OS=Gallus gallus OX=9031 GN=NDUFA12 PE=1 SV=2 CANONICAL=F1NW95-1" }, "locus": { "chromosome": "1", "start_pos": 45367643, "end_pos": 45360290, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010023036.1", "url": "https://www.ensembl.org/id/ENSGALT00010023036.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010013327.1", "url": "https://www.ensembl.org/id/ENSGALP00010013327.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:417907", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417907", "resource": "KEGG Pathway" }, { "id": "R-GGA-611105", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-611105", "resource": "Reactome", "description": "Respiratory electron transport" }, { "id": "R-GGA-6799198", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6799198", "resource": "Reactome", "description": "Complex I biogenesis" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2N3G4-1", "protein_name": "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12", "gene_name": "Ndufa12", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MEKKMELLQVLRRGLHQVTGHGGLRGFLKVFFRANDVKLGTLVGEDKYGNKYYEDNKQFFGRHRWVIYTTEMNGKNTFWDVDGSMVPPEWHRWLHCMTDDPPTTKPPIAHKFIWANHKFNVSGTPEQYVPYSTTRKKIHEWVPPSTPYK", "length": 149 }, "evidence": [ { "id": "F1NW95", "url": "https://omabrowser.org/oma/group/F1NW95/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "F1LXA0-1", "protein_name": "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12", "gene_name": "Ndufa12", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "TQFRMEQLRVLKRGLQQVTGHGGLRGLLRVFFRANDIRLGTLVGEDKYGNKYYEDNKQFFGRHRWVIYTTEMNGKNTFWDVDGSMVPPEWHRWLHCMTDDPPTTKPLTARKFIWTNHKFNVSATPEQYVPYSTTRKKIQEWVPPSTPYK", "length": 149 }, "evidence": [ { "id": "F1NW95", "url": "https://omabrowser.org/oma/group/F1NW95/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1SQP4-1", "protein_name": "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12", "gene_name": "NDUFA12", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MELVQVLRRGLQQVSGHGGLRGYLRVLFRANDVRVGTLVGEDKYGNKYYEDNKQFFGRHRWVIYTTEMNGRDTFWDVDGSMVPPEWHRWLHCMTDDPPTTKPPTARKYIWTNHKFNVSGTPQQYVPYSTTRKKIQEWVPPSTPYK", "length": 145 }, "evidence": [ { "id": "F1NW95", "url": 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"MELVQVLKRGLQQITGHGGLRGYLRVFFRTNDAKVGTLVGEDKYGNKYYEDNKQFFGRHRWVVYTTEMNGKNTFWDVDGSMVPPEWHRWLHSMTDDPPTTKPLTARKFIWTNHKFNVTGTPEQYVPYSTTRKKIQEWIPPSTPYK", "length": 145 }, "evidence": [ { "id": "F1NW95", "url": "https://omabrowser.org/oma/group/F1NW95/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "F1NW95", "url": "https://www.uniprot.org/uniprotkb/F1NW95" } ], "pmid": "" }, { "name": "respiratory chain complex I", "id": "GO:0045271", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045271", "evidence": [ { "database": "UniProtKB", "id": "F1NW95", "url": "https://www.uniprot.org/uniprotkb/F1NW95" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "mitochondrial ATP synthesis coupled electron transport", "id": "GO:0042775", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042775", "evidence": [ { "database": "UniProtKB", "id": "F1NW95", "url": "https://www.uniprot.org/uniprotkb/F1NW95" } ], "pmid": "" }, { "name": "respiratory electron transport chain", "id": "GO:0022904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022904", "evidence": [ { "database": "UniProtKB", "id": "F1NW95", "url": "https://www.uniprot.org/uniprotkb/F1NW95" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 117, "end_pos": 119, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1NUJ7-1", "uniprot_ac": "F1NUJ7", "uniprot_id": "F1NUJ7_CHICK", "mass": { "chemical_mass": 14255.0, "monoisotopic_mass": 14255.0 }, "refseq": { "ac": "NP_001264629", "name": "gastrotropin", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264629" }, "gene_names": [ { "name": "FABP6", "type": "recommended", "evidence": [ { "id": "F1NUJ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NUJ7" } ] }, { "name": "FABP6", "type": "synonym", "evidence": [ { "id": "NP_001264629", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264629" } ] }, { "name": "gastrotropin", "type": "synonym", "evidence": [ { "id": "NP_001264629", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264629" } ] } ], "protein_names": [ { "name": "Fatty acid binding protein 6", "type": "synonym", "evidence": [ { "id": "F1NUJ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NUJ7/entry#names_and_taxonomy" } ] }, { "name": "fatty acid binding protein 6, ileal", "type": "synonym", "evidence": [ { "id": "NP_001264629", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264629" } ] }, { "name": "gastrotropin", "type": "synonym", "evidence": [ { "id": "NP_001264629", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264629" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: HAEK01080247.1, BU336217.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA103992290, SAMEA103992323 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000256.1. On Sep 23, 2021 this sequence version replaced NP_001264629.1. Transcript Variant: This variant (2) uses an alternate splice site in the 5' UTR compared to variant 1. Both variants 1 and 2 encode the same protein.", "evidence": [ { "database": "RefSeq", "id": "NP_001264629", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264629" } ] }, { "annotation": "A BABP in a ternary complex with two bile acid molecules, obtained by employing a variety of NMR experiments.", "evidence": [ { "database": "RefSeq", "id": "NP_001264629", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264629" }, { "database": "PubMed", "id": "17929837", "url": "https://glygen.org/publication/PubMed/17929837" } ] }, { "annotation": "In cL-BABP, the interactions between this conserved water molecule and the three residues are present in the crystal of both apo- and holo-cL-BABP but are lost immediately after the start of molecular dynamics.", "evidence": [ { "database": "RefSeq", "id": "NP_001264629", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264629" }, { "database": "PubMed", "id": "18654997", "url": "https://glygen.org/publication/PubMed/18654997" } ] }, { "annotation": "The crystal structure of chicken liver basic type liver (Lb)-FABP complexed with cholic acid provides a model that describes Lb-FABP more accurately as a liver bile acid-binding protein than as a liver fatty acid-binding protein.", "evidence": [ { "database": "RefSeq", "id": "NP_001264629", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264629" }, { "database": "PubMed", "id": "15518556", "url": "https://glygen.org/publication/PubMed/15518556" } ] }, { "annotation": "The presence of partly folded states under acidic conditions in solution suggests the possibility that membrane binding of liver bile acid-binding protein occurs via this state.", "evidence": [ { "database": "RefSeq", "id": "NP_001264629", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264629" }, { "database": "PubMed", "id": "15938638", "url": "https://glygen.org/publication/PubMed/15938638" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NUJ7", "url": "https://www.uniprot.org/uniprotkb/F1NUJ7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "FABP6", "url": "https://www.uniprot.org/uniprotkb/F1NUJ7", "locus": { "chromosome": "13", "start_pos": 7494444, "end_pos": 7532099, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010009202", "url": "https://www.ensembl.org/id/ENSGALG00010009202" } ] } } ], "crossref": [ { "id": "F1NUJ7", "url": "https://alphafold.ebi.ac.uk/entry/F1NUJ7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000001445", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000001445", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd19446", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd19446", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "416154", "url": "https://www.ncbi.nlm.nih.gov/gene/416154", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "2LBA", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=2LBA&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "IPR000463", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000463", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012674", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012674", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR031259", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031259", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:416154", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416154", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "EMETVGN", "url": "https://omabrowser.org/oma/group/EMETVGN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y9B5", "url": "https://www.orthodb.org/?gene=A0A8V0Y9B5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NUJ7", "url": "https://www.orthodb.org/?gene=F1NUJ7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11955", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11955", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "pdb_00002lba", "url": "https://www.rcsb.org/structure/pdb_00002lba", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "2LBA", "url": "https://www.rcsb.org/structure/2LBA", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "PF14651", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14651", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-159418", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-159418", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-163560", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-163560", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001264629", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264629", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Y9B5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9B5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y9B5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9B5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NUJ7", "url": "https://www.uniprot.org/uniprotkb/F1NUJ7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NUJ7-1", "url": "https://www.uniprot.org/uniprotkb/F1NUJ7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAFTGKYEFESDENYDDFVKKIGLPADKIEMGRNCKIVTEVVQNGNDFTWTQHFPGGRTTTNSFTIDKEADMETMGGRKFKATVKMEGGKIVADFPNYHHTAEISGGKLVEISTSSGVVYKRTSKKIA", "length": 128, "header": "tr|F1NUJ7-1|F1NUJ7_CHICK Isoform 1 of Fatty acid binding protein 6 OS=Gallus gallus OX=9031 GN=FABP6 PE=1 SV=3 CANONICAL=F1NUJ7-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Y9B5-1", "url": "https://www.uniprot.org/uniprotkb/F1NUJ7/entry#A0A8V0Y9B5-1", "sequence": { "sequence": "MVAAILLFQPHHQGNMAFTGKYEFESDENYDDFVKKIGLPADKIEMGRNCKIVTEVVQNGNDFTWTQHFPGGRTTTNSFTIDKEADMETMGGRKFKATVKMEGGKIVADFPNYHHTAEISGGKLVEISTSSGVVYKRTSKKIA", "length": 143, "header": "tr|A0A8V0Y9B5-1|A0A8V0Y9B5_CHICK Computationally mapped isoform of Fatty acid binding protein 6 OS=Gallus gallus OX=9031 GN=FABP6 PE=3 SV=1 CANONICAL=F1NUJ7-1" }, "locus": { "chromosome": "13", "start_pos": 7517809, "end_pos": 7494518, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010021951.1", "url": "https://www.ensembl.org/id/ENSGALT00010021951.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010012570.1", "url": "https://www.ensembl.org/id/ENSGALP00010012570.1" } ] } }, { "isoform_ac": "F1NUJ7-1", "url": "https://www.uniprot.org/uniprotkb/F1NUJ7/entry#F1NUJ7-1", "sequence": { "sequence": "MAFTGKYEFESDENYDDFVKKIGLPADKIEMGRNCKIVTEVVQNGNDFTWTQHFPGGRTTTNSFTIDKEADMETMGGRKFKATVKMEGGKIVADFPNYHHTAEISGGKLVEISTSSGVVYKRTSKKIA", "length": 128, "header": "tr|F1NUJ7-1|F1NUJ7_CHICK Isoform 1 of Fatty acid binding protein 6 OS=Gallus gallus OX=9031 GN=FABP6 PE=1 SV=3 CANONICAL=F1NUJ7-1" }, "locus": { "chromosome": "13", "start_pos": 7498220, "end_pos": 7494518, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010021958.1", "url": "https://www.ensembl.org/id/ENSGALT00010021958.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010012574.1", "url": "https://www.ensembl.org/id/ENSGALP00010012574.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Crystal structure of chicken liver basic fatty acid-binding protein complexed with cholic acid.", "journal": "Biochemistry", "date": "2004-11-09", "authors": "Nichesola Daniele, Perduca Massimiliano, Capaldi Stefano, Carrizo Maria E, Righetti Pier Giorgio, Monaco Hugo L", "evidence": [ { "database": "RefSeq", "id": "NP_001264629", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264629" } ], "reference": [ { "type": "PubMed", "id": "15518556", "url": "https://glygen.org/publication/PubMed/15518556" } ] }, { "title": "Chicken liver bile acid-binding protein is in a compact partly folded state at acidic pH. Its relevance to the interaction with lipid membranes.", "journal": "Biochemistry", "date": "2005-06-14", "authors": "Nolan Ver\u00f3nica, Perduca Massimiliano, Monaco Hugo L, Montich Guillermo G", "evidence": [ { "database": "RefSeq", "id": "NP_001264629", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264629" } ], "reference": [ { "type": "PubMed", "id": "15938638", "url": "https://glygen.org/publication/PubMed/15938638" } ] }, { "title": "Structural and dynamic determinants of ligand binding in the ternary complex of chicken liver bile acid binding protein with two bile salts revealed by NMR.", "journal": "Biochemistry", "date": "2007-11-06", "authors": "Eliseo Tommaso, Ragona Laura, Catalano Maddalena, Assfalg Michael, Paci Maurizio, Zetta Lucia, Molinari Henriette, Cicero Daniel O", "evidence": [ { "database": "RefSeq", "id": "NP_001264629", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264629" } ], "reference": [ { "type": "PubMed", "id": "17929837", "url": "https://glygen.org/publication/PubMed/17929837" } ] }, { "title": "Structural and dynamic roles of permanent water molecules in ligand molecular recognition by chicken liver bile acid binding protein.", "journal": "Journal of molecular recognition : JMR", "date": "2008", "authors": "Ricchiuto Piero, Rocco Alessandro Guerini, Gianazza Elisabetta, Corrada Dario, Beringhelli Tiziana, Eberini Ivano", "evidence": [ { "database": "RefSeq", "id": "NP_001264629", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264629" } ], "reference": [ { "type": "PubMed", "id": "18654997", "url": "https://glygen.org/publication/PubMed/18654997" } ] }, { "title": "Structural requirements for cooperativity in ileal bile acid-binding proteins.", "journal": "J. Biol. Chem.", "date": "2011", "authors": "Zanzoni Serena, Assfalg Michael, Giorgetti Alejandro, D'Onofrio Mariapina, Molinari Henriette", "evidence": [ { "database": "UniProtKB", "id": "F1NUJ7", "url": "https://www.uniprot.org/uniprotkb/F1NUJ7" } ], "reference": [ { "type": "PubMed", "id": "21917914", "url": "https://glygen.org/publication/PubMed/21917914" } ] } ], "pathway": [ { "id": "gga:416154", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416154", "resource": "KEGG Pathway" }, { "id": "R-GGA-159418", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-159418", "resource": "Reactome", "description": "Recycling of bile acids and salts" }, { "id": "R-GGA-163560", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-163560", "resource": "Reactome", "description": "Triglyceride catabolism" } ], "orthologs": [ { "uniprot_canonical_ac": "F1RR40-1", "protein_name": "Fatty acid binding protein 6", "gene_name": "FABP6", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "PASSFGSWTSQLSSGMAFTGKYEIESEKNYDEFMKRLALPSDAIDKARNLKIISEVKQDGQNFTWSQQYPGGHSITNTFTIGKECDIETIGGKKFKATVQMEGGKVVVNSPNYHHTAEIVDGKLVEVSTVGGVSYERVSKKLA", "length": 143 }, "evidence": [ { "id": "F1NUJ7", "url": "https://omabrowser.org/oma/group/F1NUJ7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P51161-1", "protein_name": "Gastrotropin", "gene_name": "FABP6", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAFTGKFEMESEKNYDEFMKLLGISSDVIEKARNFKIVTEVQQDGQDFTWSQHYSGGHTMTNKFTVGKESNIQTMGGKTFKATVQMEGGKLVVNFPNYHQTSEIVGDKLVEVSTIGGVTYERVSKRLA", "length": 128 }, "evidence": [ { "id": "F1NUJ7", "url": "https://omabrowser.org/oma/group/F1NUJ7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q3T0Z2-1", "protein_name": "Gastrotropin", "gene_name": "FABP6", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAFTGKYETESEKNYDEFMKRLGLSSDRIEKGRNFKVISEIQQDGQNFTWSQHYPGGHSISNNFTIGKETEMETVGNKKFKVTVKMEGGKVVVDSANYHHTVEIVDGKLVEVSTFGGVIYERVSKKVA", "length": 128 }, "evidence": [ { "id": "F1NUJ7", "url": "https://omabrowser.org/oma/group/F1NUJ7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "fatty acid binding", "id": "GO:0005504", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005504", "evidence": [ { "database": "UniProtKB", "id": "F1NUJ7", "url": "https://www.uniprot.org/uniprotkb/F1NUJ7" } ], "pmid": "" }, { "name": "lipid binding", "id": "GO:0008289", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008289", "evidence": [ { "database": "UniProtKB", "id": "F1NUJ7", "url": "https://www.uniprot.org/uniprotkb/F1NUJ7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1NUJ7", "url": "https://www.uniprot.org/uniprotkb/F1NUJ7" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F1NUJ7", "url": "https://www.uniprot.org/uniprotkb/F1NUJ7" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1NUJ7", "url": "https://www.uniprot.org/uniprotkb/F1NUJ7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "fatty acid transport", "id": "GO:0015908", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015908", "evidence": [ { "database": "UniProtKB", "id": "F1NUJ7", "url": "https://www.uniprot.org/uniprotkb/F1NUJ7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "2lba", "pdb_chain": "a", "start_pos": 1, "end_pos": 128, "overlap": "1.0", "method": "NMR_Spectroscopy", "type": "experimental", "resolution": 100.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/2lba.pdb", "url_external": "https://www.rcsb.org/structure/2lba" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1NUJ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NUJ7" }, { "id": "PS00214", "database": "PROSITE", "url": "https://prosite.expasy.org/PS00214" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Cytosolic fatty-acid binding proteins", "eco_id": "ECO_0000259", "start_pos": 5, "end_pos": 22, "start_aa": "Gly", "end_aa": "Ile", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 5 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "F1NNE7-1", "uniprot_ac": "F1NNE7", "uniprot_id": "F1NNE7_CHICK", "mass": { "chemical_mass": 117003.0, "monoisotopic_mass": 117003.0 }, "refseq": { "ac": "XP_424862", "name": "leucyl-cystinyl aminopeptidase isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_424862" }, "gene_names": [ { "name": "LNPEP", "type": "recommended", "evidence": [ { "id": "F1NNE7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NNE7" } ] }, { "name": "LNPEP", "type": "synonym", "evidence": [ { "id": "XP_424862", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_424862" } ] } ], "protein_names": [ { "name": "Leucyl-cystinyl aminopeptidase", "type": "recommended", "evidence": [ { "id": "F1NNE7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NNE7/entry#names_and_taxonomy" } ] }, { "name": "3.4.11.3", "type": "synonym", "evidence": [ { "id": "F1NNE7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NNE7/entry#names_and_taxonomy" } ] }, { "name": "Oxytocinase", "type": "synonym", "evidence": [ { "id": "F1NNE7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NNE7/entry#names_and_taxonomy" } ] }, { "name": "leucyl-cystinyl aminopeptidase isoform X2", "type": "synonym", "evidence": [ { "id": "XP_424862", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_424862" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052572.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Dec 16, 2011 this sequence version replaced XP_424862.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_424862", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_424862" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NNE7", "url": "https://www.uniprot.org/uniprotkb/F1NNE7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LNPEP", "url": "https://www.uniprot.org/uniprotkb/F1NNE7", "locus": { "chromosome": "Z", "start_pos": 52280210, "end_pos": 52330683, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013246", "url": "https://www.ensembl.org/id/ENSGALG00010013246" } ] } } ], "crossref": [ { "id": "F1NNE7", "url": "https://alphafold.ebi.ac.uk/entry/F1NNE7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000015301", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000015301", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd09601", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09601", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "427279", "url": "https://www.ncbi.nlm.nih.gov/gene/427279", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001930", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001930", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014782", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014782", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024571", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024571", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027268", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027268", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034016", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034016", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042097", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042097", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045357", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045357", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050344", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050344", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "AWDFIQV", "url": "https://omabrowser.org/oma/group/AWDFIQV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YL83", "url": "https://www.orthodb.org/?gene=A0A8V0YL83", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NNE7", "url": "https://www.orthodb.org/?gene=F1NNE7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11533", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11533", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11533:SF42", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11533:SF42", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01433", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01433", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF11838", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11838", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17900", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17900", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-1236977", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1236977", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-983168", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983168", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_424862", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_424862", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YL83", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL83", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YL83-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL83-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NNE7", "url": "https://www.uniprot.org/uniprotkb/F1NNE7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NNE7-1", "url": "https://www.uniprot.org/uniprotkb/F1NNE7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEPFPSDQIQLPRNMIENSMFEEEPDVVDLAKEPCLHPLEPDEVEYEPRTSRLLVRGLGEHEMDDDEEDYESSAKLLGMSFINRSSGLRNNMSVYRQSPDGSCSVPSTRTMLICTGVLVIAVSVIMVIYLLPKCTFTKEGCHKKNRTMELIYPLATNGKLFPWAKIRLPSDVVPLHYDLDLQPNLTTLKFTGSVKIVVNVTQVTKKIVLHSSGLNITKATITSTGGSQEKAVELLEYPLHDQIAVMAPESLLAGQNYTVNLEYSSNLSDTYYGFYRVSYKDENSKQRWFAATQFEPLAARSAFPCFDEPALKATFSIRIKRDEKLSTLSNMPKKATTPVTKGIVQDEFFVSLKMSTYLVAFVVADLKNISMETNGSLVSVHAIPQHINQVEYALNTAVKLLEFYEKYFLINYPLEKLDLVAIPDFQSGAMENWGLITFRETTLLFDNNASSARDKKLITAVIAHELAHQWFGNLVTMEWWNDLWLNEGFATFMEYFAMEEIFPELHSDEDFLNLIFKAMMKDSLNSSHPVSSAVQSSEQIEEMFDALSYIKGASLLMMLKHYLTKDVFQAGIEIYLHNHKYGSAQSDDLWDSMNEITNGTLDVKKLMKTWILHKGFPLVTVNRKGKIISLHQEKFLYSVEPDNWTSDTSYLWDIPLTYTTNRCNFTHCINAYLLDQKSAVIELPEEVEWIKFNVDMNGYYIVNYDEDWETLIDLLKKNHTALSAKDRANLINNIFSLASLGKEPLKKAFELIDYLKEESSTAPLSQALFQLGLIFGLLEKRGEQQLAARVMYRIECLLGNKIDQQNWTDDGTISERELRSMLLTFACTHDIRNCRTAASKMFDEWMKSNGTMSLPSDLMKAIFITGAKTNDGWEFLLKMYSSPVPEAEKSKMIEALASTEDVRKMMWLMQNSLEGEVIRTQELSHIIATISHSLPGHLLAWDFVKENWEKLTRKFHLGSYTIQNIISSSTSQFATKVHLLEVKTFFESKSEESSKLRCVKEAIDTIQLNIQWMETNLAKLQEWL", "length": 1024, "header": "tr|F1NNE7-1|F1NNE7_CHICK Isoform 1 of Leucyl-cystinyl aminopeptidase OS=Gallus gallus OX=9031 GN=LNPEP PE=1 SV=2 CANONICAL=F1NNE7-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YL83-1", "url": "https://www.uniprot.org/uniprotkb/F1NNE7/entry#A0A8V0YL83-1", "sequence": { "sequence": "MVFLPQVEDGAINLHSDQIQLPRNMIENSMFEEEPDVVDLAKEPCLHPLEPDEVEYEPRTSRLLVRGLGEHEMDDDEEDYESSAKLLGMSFINRSSGLRNNMSVYRQSPDGSCSVPSTRTMLICTGVLVIAVSVIMVIYLLPKCTFTKEGCHKKNRTMELIYPLATNGKLFPWAKIRLPSDVVPLHYDLDLQPNLTTLKFTGSVKIVVNVTQVTKKIVLHSSGLNITKATITSTGGSQEKAVELLEYPLHDQIAVMAPESLLAGQNYTVNLEYSSNLSDTYYGFYRVSYKDENSKQRWFAATQFEPLAARSAFPCFDEPALKATFSIRIKRDEKLSTLSNMPKKATTPVTKGIVQDEFFVSLKMSTYLVAFVVADLKNISMETNGSLVSVHAIPQHINQVEYALNTAVKLLEFYEKYFLINYPLEKLDLVAIPDFQSGAMENWGLITFRETTLLFDNNASSARDKKLITAVIAHELAHQWFGNLVTMEWWNDLWLNEGFATFMEYFAMEEIFPELHSDEDFLNLIFKAMMKDSLNSSHPVSSAVQSSEQIEEMFDALSYIKGASLLMMLKHYLTKDVFQAGIEIYLHNHKYGSAQSDDLWDSMNEITNGTLDVKKLMKTWILHKGFPLVTVNRKGKIISLHQEKFLYSVEPDNWTSDTSYLWDIPLTYTTNRCNFTHCINAYLLDQKSAVIELPEEVEWIKFNVDMNGYYIVNYDEDWETLIDLLKKNHTALSAKDRANLINNIFSLASLGKEPLKKAFELIDYLKEESSTAPLSQALFQLGLIFGLLEKRGEQQLAARVMYRIECLLGNKIDQQNWTDDGTISERELRSMLLTFACTHDIRNCRTAASKMFDEWMKSNGTMSLPSDLMKAIFITGAKTNDGWEFLLKMYSSPVPEAEKSKMIEALASTEDVRKMMWLMQNSLEGEVIRTQELSHIIATISHSLPGHLLAWDFVKENWEKLTRKFHLGSYTIQNIISSSTSQFATKVHLLEVKTFFESKSEESSKLRCVKEAIDTIQLNIQWMETNLAKLQEWL", "length": 1034, "header": "tr|A0A8V0YL83-1|A0A8V0YL83_CHICK Computationally mapped isoform of Leucyl-cystinyl aminopeptidase OS=Gallus gallus OX=9031 GN=LNPEP PE=1 SV=1 CANONICAL=F1NNE7-1" }, "locus": { "chromosome": "Z", "start_pos": 52318733, "end_pos": 52282136, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031835.1", "url": "https://www.ensembl.org/id/ENSGALT00010031835.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018640.1", "url": "https://www.ensembl.org/id/ENSGALP00010018640.1" } ] } }, { "isoform_ac": "F1NNE7-1", "url": "https://www.uniprot.org/uniprotkb/F1NNE7/entry#F1NNE7-1", "sequence": { "sequence": "MEPFPSDQIQLPRNMIENSMFEEEPDVVDLAKEPCLHPLEPDEVEYEPRTSRLLVRGLGEHEMDDDEEDYESSAKLLGMSFINRSSGLRNNMSVYRQSPDGSCSVPSTRTMLICTGVLVIAVSVIMVIYLLPKCTFTKEGCHKKNRTMELIYPLATNGKLFPWAKIRLPSDVVPLHYDLDLQPNLTTLKFTGSVKIVVNVTQVTKKIVLHSSGLNITKATITSTGGSQEKAVELLEYPLHDQIAVMAPESLLAGQNYTVNLEYSSNLSDTYYGFYRVSYKDENSKQRWFAATQFEPLAARSAFPCFDEPALKATFSIRIKRDEKLSTLSNMPKKATTPVTKGIVQDEFFVSLKMSTYLVAFVVADLKNISMETNGSLVSVHAIPQHINQVEYALNTAVKLLEFYEKYFLINYPLEKLDLVAIPDFQSGAMENWGLITFRETTLLFDNNASSARDKKLITAVIAHELAHQWFGNLVTMEWWNDLWLNEGFATFMEYFAMEEIFPELHSDEDFLNLIFKAMMKDSLNSSHPVSSAVQSSEQIEEMFDALSYIKGASLLMMLKHYLTKDVFQAGIEIYLHNHKYGSAQSDDLWDSMNEITNGTLDVKKLMKTWILHKGFPLVTVNRKGKIISLHQEKFLYSVEPDNWTSDTSYLWDIPLTYTTNRCNFTHCINAYLLDQKSAVIELPEEVEWIKFNVDMNGYYIVNYDEDWETLIDLLKKNHTALSAKDRANLINNIFSLASLGKEPLKKAFELIDYLKEESSTAPLSQALFQLGLIFGLLEKRGEQQLAARVMYRIECLLGNKIDQQNWTDDGTISERELRSMLLTFACTHDIRNCRTAASKMFDEWMKSNGTMSLPSDLMKAIFITGAKTNDGWEFLLKMYSSPVPEAEKSKMIEALASTEDVRKMMWLMQNSLEGEVIRTQELSHIIATISHSLPGHLLAWDFVKENWEKLTRKFHLGSYTIQNIISSSTSQFATKVHLLEVKTFFESKSEESSKLRCVKEAIDTIQLNIQWMETNLAKLQEWL", "length": 1024, "header": "tr|F1NNE7-1|F1NNE7_CHICK Isoform 1 of Leucyl-cystinyl aminopeptidase OS=Gallus gallus OX=9031 GN=LNPEP PE=1 SV=2 CANONICAL=F1NNE7-1" }, "locus": { "chromosome": "Z", "start_pos": 52330592, "end_pos": 52282136, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031837.1", "url": "https://www.ensembl.org/id/ENSGALT00010031837.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018642.1", "url": "https://www.ensembl.org/id/ENSGALP00010018642.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "R-GGA-1236977", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1236977", "resource": "Reactome", "description": "Endosomal/Vacuolar pathway" }, { "id": "R-GGA-983168", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983168", "resource": "Reactome", "description": "Antigen processing: Ubiquitination & Proteasome degradation" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287B4N1-1", "protein_name": "Leucyl-cystinyl aminopeptidase", "gene_name": "LNPEP", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEPFTNDRLQLPRNMIENSMFEEEPDVVDLAKEPCLHPLEPDEVEYEPRGSRLLVRGLGEHEMDEDEEDYESSAKLLGMSFMNRSSGLRNSATGYRQNSDGTCSVPSVRTMVVCAFVIVVAVSVIMVIYLLPRCTFTKEGCHKKNQSLGLIQPLATNGKLFPWAQVRLPTAIMPVRYELNLHPNLTSMTFKGSVTISLQALQATWNIILHSTGHNISRVTFVSAVSSQEKQVEVLEYPFHEQIAIVAPEALLEGHNYTLKIEYSSNISSSYYGFYGISYTDENNQKKYFAATQFEPLAARSAFPCFDEPAFKATFIIRIVRDEQYTALSNMPKKLSVITEDGLVQDEFFESVKMSTYLVAFIVGELKNLSQDVNGTLVSIYAVPEKIGQVHHALETTVKLLEFYQNYFEIQYPLKKLDLVAIPDFEAGAMENWGLLTFREETLLYDNNTSSVTDRKLVTKIIAHELAHQWFGNLVTMQWWNDVWLNEGFATFMEYFSLEKIFQELSSYEDFLDARFKTLKKDSLNSSHPISSSSVQSSEQIEEMFDSLSYFKGASLLLMLKTYLSEDIFQHAVVLYLHNHSYASVHSDDLWDTFNEVTNKTLDVKKMMKTWTLQKGFPLVTVQRKGKELLVQQERFSLNMKPEIQPSDASYLWHIPLSYVTDGRNYSKHRSVSLLDEKSDVINLTEEVQWVKVNIDMTGYYIVHYADADWEALIKQLKINPYVLSDKDRASLINNIFELAGIGKVPLQRAFDLIDYLRNETYTAPITEALFQTELIYNLLEKVGYMDVASRLVTKVYKLLQSQIQQQTWTDEGTPSARELRSVLLDFACTHDLENCSTAALKLFNDWMASNGTQSLPTDVMTTVFKVGAKTDKGWSFLLSKYVSGGSEAEKNKILEALASSEDVWKLYWLMKNSLSGDIIRTQKLSFIIRTVGRHFPGHLLAWDFVKENWNTLVQKFHLGSYTIQSIVAGSTHLFATRTHFSEVQAFFGNQSEATFRLRCVQEALEVIQLNIQWMEKNHKSLMSWL", "length": 1026 }, "evidence": [ { "id": "F1NNE7", "url": "https://omabrowser.org/oma/group/F1NNE7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P37898-1", "protein_name": "Alanine/arginine aminopeptidase", "gene_name": "AAP1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSREVLPNNVTPLHYDITLEPNFRAFTFEGSLKIDLQINDHSINSVQINYLEIDFHSARIEGVNAIEVNKNENQQKATLVFPNGTFENLGPSAKLEIIFSGILNDQMAGFYRAKYTDKVTGETKYMATTQMEATDARRAFPCFDEPNLKATFAVTLVSESFLTHLSNMDVRNETIKEGKKYTTFNTTPKMSTYLVAFIVADLRYVESNNFRIPVRVYSTPGDEKFGQFAANLAARTLRFFEDTFNIEYPLPKMDMVAVHEFSAGAMENWGLVTYRVIDLLLDIENSSLDRIQRVAEVIQHELAHQWFGNLVTMDWWEGLWLNEGFATWMSWYSCNKFQPEWKVWEQYVTDNLQRALNLDSLRSSHPIEVPVNNADEINQIFDAISYSKGSSLLRMISKWLGEETFIKGVSQYLNKFKYGNAKTGDLWDALADASGKDVCSVMNIWTKRVGFPVLSVKEHKNKITLTQHRYLSTGDVKEEEDTTIYPILLALKDSTGIDNTLVLNEKSATFELKNEEFFKINGDQSGIFITSYSDERWAKLSKQANLLSVEDRVGLVADAKALSASGYTSTTNFLNLISNWKNEDSFVVWEQIINSLSALKSTWVFEPEDILNALDKFTLDLVLNKLSELGWNIGEDDSFAIQRLKVTLFSAACTSGNEKMQSIAVEMFEEYANGNKQAIPALFKAVVFNTVARLGGENNYEKIFNIYQNPVSSEEKIIALRALGRFEDKELLERTLSYLLDGTVLNQDFYIPMQGIRVHKKGIERLWAWMQEHWDEIAKRLQPGSPVLGGVLTLGLTNFTSFEALEKISAFYSRKVTKGFDQTLAQALDTIRSKAQWVSRDREIVATYLREHEYDQ", "length": 856 }, "evidence": [ { "id": "F1NNE7", "url": "https://omabrowser.org/oma/group/F1NNE7/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P97629-1", "protein_name": "Leucyl-cystinyl aminopeptidase", "gene_name": "Lnpep", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "METFTNDRLQLPRNMIENSMFEEEPDVVDLAKEPCLHPLEPDEVEYEPRGSRLLVRGLGEHEMDEDEEDYESSAKLLGMSFMNRSSGLRNSATGYRQSPDGTCSVPSARTLVICVFVIVVAVSVIMVIYLLPRCTFTKEGCHKTNQSAELIQPIATNGKVFPWAQIRLPTAIIPQRYELSLHPNLTSMTFRGSVTISLQALQDTRDIILHSTGHNISSVTFMSAVSSQEKQVEILEYPYHEQIAVVAPESLLTGHNYTLKIEYSANISNSYYGFYGITYTDKSNEKKNFAATQFEPLAARSAFPCFDEPAFKATFIIKITRDEHHTALSNMPKKSSVPTEEGLIQDEFSESVKMSTYLVAFIVGEMRNLSQDVNGTLVSVYAVPEKIDQVYHALDTTVKLLEFYQNYFEIQYPLKKLDLVAIPDFEAGAMENWGLLTFREETLLYDNATSSVADRKLVTKIIAHELAHQWFGNLVTMQWWNDLWLNEGFATFMEYFSVEKIFKELNSYEDFLDARFKTMRKDSLNSSHPISSSVQSSEQIEEMFDSLSYFKGASLLLMLKSYLSEDVFQHAIILYLHNHSYAAIQSDDLWDSFNEVTGKTLDVKKMMKTWTLQKGFPLVTVQRKGTELLLQQERFFPSMQPEIQDSDTSHLWHIPISYVTDGRNYSEYRSVSLLDKKSDVINLTEQVQWVKVNTNMTGYYIVHYAHDGWAALINQLKRNPYVLSDKDRANLINNIFELAGLGKVPLQMAFDLIDYLRNETHTAPITEALFQTDLIYNLLEKLGHMDLSSRLVTRVHKLLQNQIQQQTWTDEGTPSMRELRSALLEFACAHSLENCTTMATKLFDGWMASNGTQSLPTDVMTTVFKVGARTEKGWLFLFSMYSSMGSEAEKDKILEALASSADAHKLYWLMKSSLDGDIIRTQKLSLIIRTVGRQFPGHLLAWDFVKENWNKLVHKFHLGSYTIQSIVAGSTHLFSTKTHLSEVQEFFENQSEATLQLRCVQEAFEVIELNIQWMARNLKTLTLWL", "length": 1025 }, "evidence": [ { "id": "F1NNE7", "url": "https://omabrowser.org/oma/group/F1NNE7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8C129-1", "protein_name": "Leucyl-cystinyl aminopeptidase", "gene_name": "Lnpep", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MESFTNDRLQLPRNMIENSMFEEEPDVVDLAKEPCLHPLEPDEVEYEPRGSRLLVRGLGEHEMDEDEEDYESSAKLLGMSFMNRSSGLRNSAAGYRQSPDGTCSLPSARTLVICVFVIVVAVSVIMVIYLLPRCTFTKEGCHKTNQSAELIQPVATNGKVFPWAQIRLPTAIIPLCYELSLHPNLTSMTFRGSVTISLQALQDTRDIILHSTGHNISRVTFMSAVSSQEKQVEILEYPYHEQIAVVAPEPLLTGHNYTLKIEYSANISNSYYGFYGITYTDKSNEKKYFAATQFEPLAARSAFPCFDEPAFKATFIIKITRNEHHTALSNMPKKSSVPAEEGLIQDEFSESVKMSTYLVAFIVGEMRNLSQDVNGTLVSVYAVPEKIGQVHHALDTTIKLLEFYQTYFEIQYPLKKLDLVAIPDFEAGAMENWGLLTFREETLLYDNATSSVADRKLVTKIIAHELAHQWFGNLVTMQWWNDLWLNEGFATFMEYFSVEKIFKELNSYEDFLDARFKTMRKDSLNSSHPISSSVQSSEQIEEMFDSLSYFKGASLLLMLKSYLSEDVFRHAVILYLHNHSYAAIQSDDLWDSFNEVTDKTLDVKKMMKTWTLQKGFPLVTVQRKGTELLLQQERFFLRMQPESQPSDTSHLWHIPISYVTDGRNYSEYRSVSLLDKKSDVINLTEQVQWVKVNSNMTGYYIVHYAHDDWTALINQLKRNPYVLSDKDRANLINNIFELAGLGKVPLRMAFDLIDYLKNETHTAPITEALFQTNLIYNLLEKLGHMDLSSRLVARVHKLLQNQIQQQTWTDEGTPSMRELRSALLEFACAHSLENCTTMATNLFDSWMASNGTQSLPTDVMVTVFKVGARTEKGWLFLFSMYSSMGSEAEKNKILEALASSEDVHKLYWLMKSSLDGDIIRTQKLSLIIRTVGRHFPGHLLAWDFVKENWNKLVHKFHLGSYTIQSIVAGSTHLFSTKTHLSEVQAFFENQSEATLKLRCVQEALEVIQLNIQWMVRNLKTLSQWL", "length": 1025 }, "evidence": [ { "id": "F1NNE7", "url": "https://omabrowser.org/oma/group/F1NNE7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9UIQ6-1", "protein_name": "Leucyl-cystinyl aminopeptidase", "gene_name": "LNPEP", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEPFTNDRLQLPRNMIENSMFEEEPDVVDLAKEPCLHPLEPDEVEYEPRGSRLLVRGLGEHEMEEDEEDYESSAKLLGMSFMNRSSGLRNSATGYRQSPDGACSVPSARTMVVCAFVIVVAVSVIMVIYLLPRCTFTKEGCHKKNQSIGLIQPFATNGKLFPWAQIRLPTAVVPLRYELSLHPNLTSMTFRGSVTISVQALQVTWNIILHSTGHNISRVTFMSAVSSQEKQAEILEYAYHGQIAIVAPEALLAGHNYTLKIEYSANISSSYYGFYGFSYTDESNEKKYFAATQFEPLAARSAFPCFDEPAFKATFIIKIIRDEQYTALSNMPKKSSVVLDDGLVQDEFSESVKMSTYLVAFIVGEMKNLSQDVNGTLVSIYAVPEKIGQVHYALETTVKLLEFFQNYFEIQYPLKKLDLVAIPDFEAGAMENWGLLTFREETLLYDSNTSSMADRKLVTKIIAHELAHQWFGNLVTMKWWNDLWLNEGFATFMEYFSLEKIFKELSSYEDFLDARFKTMKKDSLNSSHPISSSVQSSEQIEEMFDSLSYFKGSSLLLMLKTYLSEDVFQHAVVLYLHNHSYASIQSDDLWDSFNEVTNQTLDVKRMMKTWTLQKGFPLVTVQKKGKELFIQQERFFLNMKPEIQPSDTSYLWHIPLSYVTEGRNYSKYQSVSLLDKKSGVINLTEEVLWVKVNINMNGYYIVHYADDDWEALIHQLKINPYVLSDKDRANLINNIFELAGLGKVPLKRAFDLINYLGNENHTAPITEALFQTDLIYNLLEKLGYMDLASRLVTRVFKLLQNQIQQQTWTDEGTPSMRELRSALLEFACTHNLGNCSTTAMKLFDDWMASNGTQSLPTDVMTTVFKVGAKTDKGWSFLLGKYISIGSEAEKNKILEALASSEDVRKLYWLMKSSLNGDNFRTQKLSFIIRTVGRHFPGHLLAWDFVKENWNKLVQKFPLGSYTIQNIVAGSTYLFSTKTHLSEVQAFFENQSEATFRLRCVQEALEVIQLNIQWMEKNLKSLTWWL", "length": 1025 }, "evidence": [ { "id": "F1NNE7", "url": "https://omabrowser.org/oma/group/F1NNE7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F1NNE7", "url": "https://www.uniprot.org/uniprotkb/F1NNE7" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "F1NNE7", "url": "https://www.uniprot.org/uniprotkb/F1NNE7" } ], "pmid": "" }, { "name": "cytoplasmic vesicle membrane", "id": "GO:0030659", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030659", "evidence": [ { "database": "UniProtKB", "id": "F1NNE7", "url": "https://www.uniprot.org/uniprotkb/F1NNE7" } ], "pmid": "" }, { "name": "cytoplasmic vesicle", "id": "GO:0031410", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031410", "evidence": [ { "database": "UniProtKB", "id": "F1NNE7", "url": "https://www.uniprot.org/uniprotkb/F1NNE7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "F1NNE7", "url": "https://www.uniprot.org/uniprotkb/F1NNE7" } ], "pmid": "" }, { "name": "regulation of blood pressure", "id": "GO:0008217", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008217", "evidence": [ { "database": "UniProtKB", "id": "F1NNE7", "url": "https://www.uniprot.org/uniprotkb/F1NNE7" } ], "pmid": "" }, { "name": "neuropeptide catabolic process", "id": "GO:0010813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010813", "evidence": [ { "database": "UniProtKB", "id": "F1NNE7", "url": "https://www.uniprot.org/uniprotkb/F1NNE7" } ], "pmid": "" }, { "name": "negative regulation of cold-induced thermogenesis", "id": "GO:0120163", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120163", "evidence": [ { "database": "UniProtKB", "id": "F1NNE7", "url": "https://www.uniprot.org/uniprotkb/F1NNE7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "F1NNE7", "url": "https://www.uniprot.org/uniprotkb/F1NNE7" } ], "pmid": "" }, { "name": "metalloaminopeptidase activity", "id": "GO:0070006", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070006", "evidence": [ { "database": "UniProtKB", "id": "F1NNE7", "url": "https://www.uniprot.org/uniprotkb/F1NNE7" } ], "pmid": "" }, { "name": "metallopeptidase activity", "id": "GO:0008237", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008237", "evidence": [ { "database": "UniProtKB", "id": "F1NNE7", "url": "https://www.uniprot.org/uniprotkb/F1NNE7" } ], "pmid": "" }, { "name": "aminopeptidase activity", "id": "GO:0004177", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004177", "evidence": [ { "database": "UniProtKB", "id": "F1NNE7", "url": "https://www.uniprot.org/uniprotkb/F1NNE7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 145, "end_pos": 147, "annotation": "n_glycosylation_sequon" }, { "start_pos": 184, "end_pos": 186, "annotation": "n_glycosylation_sequon" }, { "start_pos": 199, "end_pos": 201, "annotation": "n_glycosylation_sequon" }, { "start_pos": 215, "end_pos": 217, "annotation": "n_glycosylation_sequon" }, { "start_pos": 256, "end_pos": 258, "annotation": "n_glycosylation_sequon" }, { "start_pos": 266, "end_pos": 268, "annotation": "n_glycosylation_sequon" }, { "start_pos": 368, "end_pos": 370, "annotation": "n_glycosylation_sequon" }, { "start_pos": 374, "end_pos": 376, "annotation": "n_glycosylation_sequon" }, { "start_pos": 448, "end_pos": 450, "annotation": "n_glycosylation_sequon" }, { "start_pos": 525, "end_pos": 527, "annotation": "n_glycosylation_sequon" }, { "start_pos": 598, "end_pos": 600, "annotation": "n_glycosylation_sequon" }, { "start_pos": 643, "end_pos": 645, "annotation": "n_glycosylation_sequon" }, { "start_pos": 664, "end_pos": 666, "annotation": "n_glycosylation_sequon" }, { "start_pos": 718, "end_pos": 720, "annotation": "n_glycosylation_sequon" }, { "start_pos": 806, "end_pos": 808, "annotation": "n_glycosylation_sequon" }, { "start_pos": 83, "end_pos": 85, "annotation": "n_glycosylation_sequon" }, { "start_pos": 849, "end_pos": 851, "annotation": "n_glycosylation_sequon" }, { "start_pos": 91, "end_pos": 93, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-GGA-1236954", "name": "Trimming of peptides by IRAP in endocytic vesicles", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "early endosome membrane, early endosome lumen", "input_participant_list": [ "R-ALL-1236722" ], "output_participant_list": [ "R-ALL-1236727", "R-ALL-8943711" ], "enzyme_list": [ "F1NNE7-1" ], "evidence": [ { "id": "R-GGA-1236954", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1236954" } ] }, { "id": "R-GGA-983162", "name": "Trimming of N-ter extended precursor fragments by cytosolic aminopeptidases", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [ "R-ALL-8942986" ], "enzyme_list": [ "A0A8V1AEU4-1", "A0A1D5P774-1", "P87362-1", "A0A8V0ZZ05-1", "F1NNE7-1" ], "evidence": [ { "id": "R-GGA-983162", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983162" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-1236722", "participant_name": "precursor peptide fragment (>16 aa) [early endosome lumen]", "crossref": [ { "id": "25676", "database": "ChEBI", "url": "" } ] }, { "participant_id": "R-ALL-1236727", "participant_name": "Antigen peptide [early endosome lumen]", "crossref": [ { "id": "25676", "database": "ChEBI", "url": "" } ] }, { "participant_id": "R-ALL-8942986", "participant_name": "L-amino acid [cytosol]", "crossref": [ { "id": "59869", "database": "ChEBI", "url": "" } ] }, { "participant_id": "R-ALL-8943711", "participant_name": "L-amino acid [early endosome lumen]", "crossref": [ { "id": "59869", "database": "ChEBI", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A0A1D5P774", "gene_name": "TPP2", "activity": [ { "ec_number": "3.4.14.10", "activity": "Release of an N-terminal tripeptide from a polypeptide.", "evidence": [ { "id": "A0A1D5P774", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P774" } ] }, { "ec_number": "3.4.14.10", "activity": "", "evidence": [ { "id": "A0A1D5P774", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P774" } ] } ] }, { "uniprot_ac": "A0A8V0ZZ05", "gene_name": "NPEPPS", "activity": [ { "ec_number": "3.4.11.-", "activity": "", "evidence": [ { "id": "A0A8V0ZZ05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZ05" } ] } ] }, { "uniprot_ac": "A0A8V1AEU4", "gene_name": "BLMH", "activity": [ { "ec_number": "3.4.22.40", "activity": "Inactivates bleomycin B2 (a cytotoxic glycometallopeptide) by hydrolysis of a carboxyamide bond of beta-aminoalanine, but also shows general aminopeptidase activity. The specificity varies somewhat with source, but amino acid arylamides of Met, Leu and Ala are preferred.", "evidence": [ { "id": "A0A8V1AEU4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEU4" } ] }, { "ec_number": "3.4.22.40", "activity": "", "evidence": [ { "id": "A0A8V1AEU4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEU4" } ] } ] }, { "uniprot_ac": "F1NNE7", "gene_name": "LNPEP", "activity": [ { "ec_number": "3.4.11.3", "activity": "Release of an N-terminal amino acid, Cys-|-Xaa-, in which the half-cystine residue is involved in a disulfide loop, notably in oxytocin or vasopressin. Hydrolysis rates on a range of aminoacyl arylamides exceed that for the cystinyl derivative, however.", "evidence": [ { "id": "F1NNE7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NNE7" } ] }, { "ec_number": "3.4.11.3", "activity": "", "evidence": [ { "id": "F1NNE7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NNE7" } ] } ] }, { "uniprot_ac": "P87362", "gene_name": "BLMH", "activity": [ { "ec_number": "3.4.22.40", "activity": "Inactivates bleomycin B2 (a cytotoxic glycometallopeptide) by hydrolysis of a carboxyamide bond of beta-aminoalanine, but also shows general aminopeptidase activity. The specificity varies somewhat with source, but amino acid arylamides of Met, Leu and Ala are preferred.", "evidence": [ { "id": "P87362", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P87362" } ] }, { "ec_number": "3.4.22.40", "activity": "", "evidence": [ { "id": "P87362", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P87362" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1NNE7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NNE7" }, { "id": "PF17900", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17900" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Aminopeptidase N-like N-terminal", "eco_id": "ECO_0000259", "start_pos": 173, "end_pos": 358, "start_aa": "Val", "end_aa": "Leu", "glycosite_overlap": "" }, { "evidence": [ { "id": "F1NNE7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NNE7" }, { "id": "PF11838", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11838" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "ERAP1-like C-terminal", "eco_id": "ECO_0000259", "start_pos": 689, "end_pos": 1007, "start_aa": "Trp", "end_aa": "Gln", "glycosite_overlap": "" }, { "evidence": [ { "id": "F1NNE7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NNE7" }, { "id": "PF01433", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01433" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Peptidase M1 membrane alanine aminopeptidase", "eco_id": "ECO_0000259", "start_pos": 392, "end_pos": 610, "start_aa": "Tyr", "end_aa": "Trp", "glycosite_overlap": "" } ], "binding_sites": [ { "evidence": [ { "id": "F1NNE7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NNE7#function" }, { "id": "F1NNE7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NNE7" }, { "id": "PIRSR634016-3", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR634016-3" } ], "binding_site_uniprot": 464, "amino_acid": "His", "chebi_lig_id": "CHEBI_29105", "ligand": "Zn(2+)", "ligand_label": "", "uniprotkb_ligand_comment": "catalytic", "eco_id": "ECO_0000256", "start_pos": 464, "end_pos": 464, "start_aa": "His", "end_aa": "His", "glycosite_overlap": "" }, { "evidence": [ { "id": "F1NNE7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NNE7#function" }, { "id": "F1NNE7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NNE7" }, { "id": "PIRSR634016-3", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR634016-3" } ], "binding_site_uniprot": 468, "amino_acid": "His", "chebi_lig_id": "CHEBI_29105", "ligand": "Zn(2+)", "ligand_label": "", "uniprotkb_ligand_comment": "catalytic", "eco_id": "ECO_0000256", "start_pos": 468, "end_pos": 468, "start_aa": "His", "end_aa": "His", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0YL83", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL83#function" }, { "id": "A0A8V0YL83", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL83" }, { "id": "PIRSR634016-3", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR634016-3" } ], "binding_site_uniprot": 474, "amino_acid": "Leu", "chebi_lig_id": "CHEBI_29105", "ligand": "Zn(2+)", "ligand_label": "", "uniprotkb_ligand_comment": "catalytic", "eco_id": "ECO_0000256", "start_pos": 474, "end_pos": 474, "start_aa": "Leu", "end_aa": "Leu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0YL83", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL83#function" }, { "id": "A0A8V0YL83", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL83" }, { "id": "PIRSR634016-3", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR634016-3" } ], "binding_site_uniprot": 478, "amino_acid": "Glu", "chebi_lig_id": "CHEBI_29105", "ligand": "Zn(2+)", "ligand_label": "", "uniprotkb_ligand_comment": "catalytic", "eco_id": "ECO_0000256", "start_pos": 478, "end_pos": 478, "start_aa": "Glu", "end_aa": "Glu", "glycosite_overlap": "" }, { "evidence": [ { "id": "F1NNE7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NNE7#function" }, { "id": "F1NNE7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NNE7" }, { "id": "PIRSR634016-3", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR634016-3" } ], "binding_site_uniprot": 487, "amino_acid": "Glu", "chebi_lig_id": "CHEBI_29105", "ligand": "Zn(2+)", "ligand_label": "", "uniprotkb_ligand_comment": "catalytic", "eco_id": "ECO_0000256", "start_pos": 487, "end_pos": 487, "start_aa": "Glu", "end_aa": "Glu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0YL83", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL83#function" }, { "id": "A0A8V0YL83", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL83" }, { "id": "PIRSR634016-3", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR634016-3" } ], "binding_site_uniprot": 497, "amino_acid": "Ala", "chebi_lig_id": "CHEBI_29105", "ligand": "Zn(2+)", "ligand_label": "", "uniprotkb_ligand_comment": "catalytic", "eco_id": "ECO_0000256", "start_pos": 497, "end_pos": 497, "start_aa": "Ala", "end_aa": "Ala", "glycosite_overlap": "" } ], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "3.4.11.3", "ec_name": "Release of an N-terminal amino acid, Cys-|-Xaa-, in which the half-cystine residue is involved in a disulfide loop, notably in oxytocin or vasopressin. Hydrolysis rates on a range of aminoacyl arylamides exceed that for the cystinyl derivative, however.", "evidence": [ { "id": "3.4.11.3", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=3.4.11.3" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 145, "end_pos": 147 }, { "start_pos": 184, "end_pos": 186 }, { "start_pos": 199, "end_pos": 201 }, { "start_pos": 215, "end_pos": 217 }, { "start_pos": 256, "end_pos": 258 }, { "start_pos": 266, "end_pos": 268 }, { "start_pos": 368, "end_pos": 370 }, { "start_pos": 374, "end_pos": 376 }, { "start_pos": 448, "end_pos": 450 }, { "start_pos": 525, "end_pos": 527 }, { "start_pos": 598, "end_pos": 600 }, { "start_pos": 643, "end_pos": 645 }, { "start_pos": 664, "end_pos": 666 }, { "start_pos": 718, "end_pos": 720 }, { "start_pos": 806, "end_pos": 808 }, { "start_pos": 83, "end_pos": 85 }, { "start_pos": 849, "end_pos": 851 }, { "start_pos": 91, "end_pos": 93 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": 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"n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1P1J2-1", "uniprot_ac": "F1P1J2", "uniprot_id": "F1P1J2_CHICK", "mass": { "chemical_mass": 57356.0, "monoisotopic_mass": 57356.0 }, "refseq": { "ac": "XP_416356", "name": "cyclic AMP-responsive element-binding protein 3-like protein 2 isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_416356" }, "gene_names": [ { "name": "CREB3L2", "type": "recommended", "evidence": [ { "id": "F1P1J2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P1J2" } ] }, { "name": "CREB3L2", "type": "synonym", "evidence": [ { "id": "XP_416356", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_416356" } ] } ], "protein_names": [ { "name": "Cyclic AMP-responsive element-binding protein 3-like protein 2", "type": "recommended", "evidence": [ { "id": "F1P1J2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P1J2/entry#names_and_taxonomy" } ] }, { "name": "cyclic AMP-responsive element-binding protein 3-like protein 2 isoform X3", "type": "synonym", "evidence": [ { "id": "XP_416356", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_416356" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 19, 2013 this sequence version replaced XP_416356.3. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_416356", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_416356" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1P1J2", "url": "https://www.uniprot.org/uniprotkb/F1P1J2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CREB3L2", "url": "https://www.uniprot.org/uniprotkb/F1P1J2", "locus": { "chromosome": "1", "start_pos": 57471318, "end_pos": 57397078, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013690", "url": "https://www.ensembl.org/id/ENSGALG00010013690" } ] } } ], "crossref": [ { "id": "F1P1J2", "url": "https://alphafold.ebi.ac.uk/entry/F1P1J2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000012877", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000012877", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd14689", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14689", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "418123", "url": "https://www.ncbi.nlm.nih.gov/gene/418123", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004827", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004827", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046347", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046347", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "CSNENME", "url": "https://omabrowser.org/oma/group/CSNENME/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YLI2", "url": "https://www.orthodb.org/?gene=A0A8V0YLI2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YNC6", "url": "https://www.orthodb.org/?gene=A0A8V0YNC6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YTB5", "url": "https://www.orthodb.org/?gene=A0A8V0YTB5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1P1J2", "url": "https://www.orthodb.org/?gene=F1P1J2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46004", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46004", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46004:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46004:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00170", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00170", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_416356", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_416356", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YLI2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLI2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLI2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLI2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YNC6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNC6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YNC6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNC6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YTB5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTB5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YTB5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTB5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1P1J2", "url": "https://www.uniprot.org/uniprotkb/F1P1J2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1P1J2-1", "url": "https://www.uniprot.org/uniprotkb/F1P1J2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEVCESGEQPPLLHWDRKLSELCEPADPDTLLGHTHFTEFLDEFSTDVLGQLLNDPFLSEKNEVMEVELSPASPAPLIQAEHSYSLCGDSRPQSPLTHISTDDNFNEGDLENEDWCLGSELTPAAIKTEPVLCETSGLTPSVSLTVTATSLDGEQAELHTDALMKPLSQRALPEIKLEPHEVDQFLNLSSKEAVDPLHLPPTPPSSHGSDSEGGQSPARSLPPSSPIQLQAAAKVVSRTASALSNSPLLTAPHKLQGTGPLILTEEEKRTLIAEGYPIPTKLPLTKAEEKVLKKIRRKIKNKISAQESRRKKKEYMDSLEKKVENCSNENSELRKKVEVLESTNRTLLQQLQRLQAMVAGKVSRSCKAASTQTGTCLMMVVLCFAVVFGSFSQSYGPYPSATKMVLPRQHSSPESYTDSIVRSRSLLIYEEPHQLEESSNPISSADRNDRHADTPKYAALALEAVPVMQQDDIMEFTIANETRLEKSVLLGLQQHRVNSEIEGNETLKIIELDRRVNATS", "length": 520, "header": "tr|F1P1J2-1|F1P1J2_CHICK Isoform 1 of Cyclic AMP-responsive element-binding protein 3-like protein 2 OS=Gallus gallus OX=9031 GN=CREB3L2 PE=3 SV=3 CANONICAL=F1P1J2-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YLI2-1", "url": "https://www.uniprot.org/uniprotkb/F1P1J2/entry#A0A8V0YLI2-1", "sequence": { "sequence": "MFCATRIVVCGGRQYEPELFPFSSLCFSDHPCVPFHTWHILTIIPAGCVEERRLPQDMAALLLFSVFIHFTEFLDEFSTDVLGQLLNDPFLSEKNEVMEVELSPASPAPLIQAEHSYSLCGDSRPQSPLTHISTDDNFNEGDLENEDWCLGSELTPAAIKTEPVLCETSGLTPSVSLTVTATSLDGEQAELHTDALMKPLSQRALPEIKLEPHEVDQFLNLSSKEAVDPLHLPPTPPSSHGSDSEGGQSPARSLPPSSPIQLQAAAKVVSRTASALSNSPLLTAPHKLQGTGPLILTEEEKRTLIAEGYPIPTKLPLTKAEEKVLKKIRRKIKNKISAQESRRKKKEYMDSLEKKVENCSNENSELRKKVEVLESTNRTLLQQLQRLQAMVAGKVSRSCKAASTQTGTCLMMVVLCFAVVFGSFSQSYGPYPSATKMVLPRQHSSPESYTDSIVRSRSLLIYEEPHQLEESSNPISSADRNDRHADTPKYAALALEAVPVMQQDDIMEFTIANETRLEKSVLLGLQQHRVNSEIEGNETLKIIELDRRVNATS", "length": 553, "header": "tr|A0A8V0YLI2-1|A0A8V0YLI2_CHICK Computationally mapped isoform of Cyclic AMP-responsive element-binding protein 3-like protein 2 OS=Gallus gallus OX=9031 GN=CREB3L2 PE=3 SV=1 CANONICAL=F1P1J2-1" }, "locus": { "chromosome": "1", "start_pos": 57469549, "end_pos": 57435683, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032889.1", "url": "https://www.ensembl.org/id/ENSGALT00010032889.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019466.1", "url": "https://www.ensembl.org/id/ENSGALP00010019466.1" } ] } }, { "isoform_ac": "A0A8V0YNC6-1", "url": "https://www.uniprot.org/uniprotkb/F1P1J2/entry#A0A8V0YNC6-1", "sequence": { "sequence": "MYSGSSLAGFRSACLDVVLVSVGDVVLHFTEFLDEFSTDVLGQLLNDPFLSEKNEVMEVELSPASPAPLIQAEHSYSLCGDSRPQSPLTHISTDDNFNEGDLENEDWCLGSELTPAAIKTEPVLCETSGLTPSVSLTVTATSLDGEQAELHTDALMKPLSQRALPEIKLEPHEVDQFLNLSSKEAVDPLHLPPTPPSSHGSDSEGGQSPARSLPPSSPIQLQAAAKVVSRTASALSNSPLLTAPHKLQGTGPLILTEEEKRTLIAEGYPIPTKLPLTKAEEKVLKKIRRKIKNKISAQESRRKKKEYMDSLEKKVENCSNENSELRKKVEVLESTNRTLLQQLQRLQAMVAGKVSRSCKAASTQTGTCLMMVVLCFAVVFGSFSQSYGPYPSATKMVLPRQHSSPESYTDSIVRSRSLLIYEEPHQLEESSNPISSADRNDRHADTPKYAALALEAVPVMQQDDIMEFTIANETRLEKSVLLGLQQHRVNSEIEGNETLKIIELDRRVNATS", "length": 512, "header": "tr|A0A8V0YNC6-1|A0A8V0YNC6_CHICK Computationally mapped isoform of Cyclic AMP-responsive element-binding protein 3-like protein 2 OS=Gallus gallus OX=9031 GN=CREB3L2 PE=3 SV=1 CANONICAL=F1P1J2-1" }, "locus": { "chromosome": "1", "start_pos": 57469549, "end_pos": 57402825, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032895.1", "url": "https://www.ensembl.org/id/ENSGALT00010032895.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019467.1", "url": "https://www.ensembl.org/id/ENSGALP00010019467.1" } ] } }, { "isoform_ac": "A0A8V0YTB5-1", "url": "https://www.uniprot.org/uniprotkb/F1P1J2/entry#A0A8V0YTB5-1", "sequence": { "sequence": "MAALLLFSVFIHFTEFLDEFSTDVLGQLLNDPFLSEKNEVMEVELSPASPAPLIQAEHSYSLCGDSRPQSPLTHISTDDNFNEGDLENEDWCLGSELTPAAIKTEPVLCETSGLTPSVSLTVTATSLDGEQAELHTDALMKPLSQRALPEIKLEPHEVDQFLNLSSKEAVDPLHLPPTPPSSHGSDSEGGQSPARSLPPSSPIQLQAAAKVVSRTASALSNSPLLTAPHKLQGTGPLILTEEEKRTLIAEGYPIPTKLPLTKAEEKVLKKIRRKIKNKISAQESRRKKKEYMDSLEKKVENCSNENSELRKKVEVLESTNRTLLQQLQRLQAMVAGKVSRSCKAASTQTGTCLMMVVLCFAVVFGSFSQSYGPYPSATKMVLPRQHSSPESYTDSIVRSRSLLIYEEPHQLEESSNPISSADRNDRHADTPKYAALALEAVPVMQQDDIMEFTIANETRLEKSVLLGLQQHRVNSEIEGNETLKIIELDRRVNATS", "length": 496, "header": "tr|A0A8V0YTB5-1|A0A8V0YTB5_CHICK Computationally mapped isoform of Cyclic AMP-responsive element-binding protein 3-like protein 2 OS=Gallus gallus OX=9031 GN=CREB3L2 PE=3 SV=1 CANONICAL=F1P1J2-1" }, "locus": { "chromosome": "1", "start_pos": 57469549, "end_pos": 57435854, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032885.1", "url": "https://www.ensembl.org/id/ENSGALT00010032885.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019465.1", "url": "https://www.ensembl.org/id/ENSGALP00010019465.1" } ] } }, { "isoform_ac": "F1P1J2-1", "url": "https://www.uniprot.org/uniprotkb/F1P1J2/entry#F1P1J2-1", "sequence": { "sequence": "MEVCESGEQPPLLHWDRKLSELCEPADPDTLLGHTHFTEFLDEFSTDVLGQLLNDPFLSEKNEVMEVELSPASPAPLIQAEHSYSLCGDSRPQSPLTHISTDDNFNEGDLENEDWCLGSELTPAAIKTEPVLCETSGLTPSVSLTVTATSLDGEQAELHTDALMKPLSQRALPEIKLEPHEVDQFLNLSSKEAVDPLHLPPTPPSSHGSDSEGGQSPARSLPPSSPIQLQAAAKVVSRTASALSNSPLLTAPHKLQGTGPLILTEEEKRTLIAEGYPIPTKLPLTKAEEKVLKKIRRKIKNKISAQESRRKKKEYMDSLEKKVENCSNENSELRKKVEVLESTNRTLLQQLQRLQAMVAGKVSRSCKAASTQTGTCLMMVVLCFAVVFGSFSQSYGPYPSATKMVLPRQHSSPESYTDSIVRSRSLLIYEEPHQLEESSNPISSADRNDRHADTPKYAALALEAVPVMQQDDIMEFTIANETRLEKSVLLGLQQHRVNSEIEGNETLKIIELDRRVNATS", "length": 520, "header": "tr|F1P1J2-1|F1P1J2_CHICK Isoform 1 of Cyclic AMP-responsive element-binding protein 3-like protein 2 OS=Gallus gallus OX=9031 GN=CREB3L2 PE=3 SV=3 CANONICAL=F1P1J2-1" }, "locus": { "chromosome": "1", "start_pos": 57469549, "end_pos": 57397205, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032896.1", "url": "https://www.ensembl.org/id/ENSGALT00010032896.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019468.1", "url": "https://www.ensembl.org/id/ENSGALP00010019468.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 202, "start_aa": "Thr", "end_pos": 202, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr202", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "F1MAB7-1", "protein_name": "Diacylglycerol kinase iota", "gene_name": "Dgki", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDAAGRGCHLLPLPAARGPARAPAASSALSPAGLCSGTASASSAAAGAVAMNPSSSAGEERGATGGSSSSGSGAGSCCLGAEGGVDPRGAGAAAAAALEEPAAAGQKEKEEALEEKLRDLTFRKQVSYRKAISRTGLQHLAPAHPLGLPVANGPAKEPRATLDWSENAVNGEHLWLETNVSGDLCYLGEENCQVRFAKSALRRKCAVCKIVVHTACIEQLEKINFRCKPTFREGGSRSPRENFVRHHWVHRRRQEGKCKQCGKGFQQKFSFHSKEIVAISCSWCKQAFHNKVTCFMLHHIEEPCSLGAHAAVIVPPTWIIKVKKPQNSLKASNRKKKRTSFKRKASKRGTEQENKGRPFVIKPISSPLMKPLLVFVNPKSGGNQGTKVLQMFMWYLNPRQVFDLSQEGPKDALELYRKVPNLRILACGGDGTVGWILSILDELQLSPQPPVGVLPLGTGNDLARTLNWGGGYTDEPVSKILCQVEDGTIVQLDRWNLHVERNPDLPPEELEDGVCKLPLNVFNNYFSLGFDAHVTLEFHESREANPEKFNSRFRNKMFYAGAAFSDFLQRSSRDLSKHVKVVCDGTDLTPKIQDLKFQCIVFLNIPRYCAGTMPWGNPGDHHDFEPQRHDDGYIEVIGFTMASLAALQVGGHGERLHQCREVMLLTYKSIPMQVDGEPCRLAPAMIRISLRNQANMVQKSKRRTSMPLLNDPQSVPDRLRIRVNKISLQDYEGLHYDKEKLREASIPLGILVVRGDCDLETCRMYIDRLQEDLQSVSSGSQRVHYQDQETSFPRAISAQRLSPRWCFLDATSADRFYRIDRSQEHLHFVMEISHDEIFILDPDMVVSQQAGTPPGMPDLVVEQASGLSDWWNPALRKRMLSDSGMITPHYEDSDLKDFSHSRVLQSPVSSEDHAILQAVITGDLMKLMESYKNGGSLLIQGPGHCSLLHYAAKTGNGEIVKYILDHGPAELLDMADSETGETALHKAACQRNRAVCQLLVDAGASLRQTDSKGKTPQERAQQAGDPDLAAYLESRQNYKIIGHEDLETAV", "length": 1050 }, "evidence": [ { "id": "F1P1J2", "url": "https://omabrowser.org/oma/group/F1P1J2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6QDP7-1", "protein_name": "Cyclic AMP-responsive element-binding protein 3-like protein 2", "gene_name": "Creb3l2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEVLESGEQSVLQWDRKLSELSEPGETEALMYHTHFSELLDEFSQNVLGQLLNDPFLSEKSVSMEVEPSPTSPAPLIQAEHSYSLSEEPRAQSPFTHVAASDGFNDEEVESEKWYLSTEFPSATIKTEPITEEQPPGLVPSVTLTITAISTPFEKEESPLDMSAGGDSSCQTLIPKIKLEPHEVDQFLNFSPKEASVDQLHLPPTPPSSHSSDSEGSLSPNPRLHPFSLSQAHSPGRAMPRGPSALSTSPLLTAPHKLQGSGPLVLTEEEKRTLIAEGYPIPTKLPLTKSEEKALKKIRRKIKNKISAQESRRKKKEYMDSLEKKVESCSTENLELRKKVEVLENTNRTLLQQLQKLQTLVMGKVSRTCKLAGTQTGTCLMVVVLCFAVAFGSLFQGYGLYPSATKMALPSQHPLSEPYTASVVRSRNLLIYEEHSSLEESSSPASAGELGGWDRGSSLLRASSGLEALPEVDLPHFIISKETSLEKSVLLELQQHLVSSKLEGNETLKVVELERRVNATF", "length": 521 }, "evidence": [ { "id": "F1P1J2", "url": "https://omabrowser.org/oma/group/F1P1J2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q70SY1-1", "protein_name": "Cyclic AMP-responsive element-binding protein 3-like protein 2", "gene_name": "CREB3L2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEVLESGEQGVLQWDRKLSELSEPGDGEALMYHTHFSELLDEFSQNVLGQLLNDPFLSEKSVSMEVEPSPTSPAPLIQAEHSYSLCEEPRAQSPFTHITTSDSFNDDEVESEKWYLSTDFPSTSIKTEPVTDEPPPGLVPSVTLTITAISTPLEKEEPPLEMNTGVDSSCQTIIPKIKLEPHEVDQFLNFSPKEAPVDHLHLPPTPPSSHGSDSEGSLSPNPRLHPFSLPQTHSPSRAAPRAPSALSSSPLLTAPHKLQGSGPLVLTEEEKRTLIAEGYPIPTKLPLSKSEEKALKKIRRKIKNKISAQESRRKKKEYMDSLEKKVESCSTENLELRKKVEVLENTNRTLLQQLQKLQTLVMGKVSRTCKLAGTQTGTCLMVVVLCFAVAFGSFFQGYGPYPSATKMALPSQHSLQEPYTASVVRSRNLLIYEEHSPPEESSSPGSAGELGGWDRGSSLLRVSGLESRPDVDLPHFIISNETSLEKSVLLELQQHLVSAKLEGNETLKVVELDRRVNTTF", "length": 520 }, "evidence": [ { "id": "F1P1J2", "url": "https://omabrowser.org/oma/group/F1P1J2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8BH52-1", "protein_name": "Cyclic AMP-responsive element-binding protein 3-like protein 2", "gene_name": "Creb3l2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEVLESGEQSVLQWDRKLSELSEPGETEALMYHTHFSELLDEFSQNVLGQLLSDPFLSEKSESMEVEPSPTSPAPLIQAEHSYSLSEEPRTQSPFTHAATSDSFNDEEVESEKWYLSTEFPSATIKTEPITEEQPPGLVPSVTLTITAISTPFEKEESPLDMNAGGDSSCQTLIPKIKLEPHEVDQFLNFSPKEASVDQLHLPPTPPSSHSSDSEGSLSPNPRLHPFSLSQAHSPARAMPRGPSALSTSPLLTAPHKLQGSGPLVLTEEEKRTLVAEGYPIPTKLPLTKSEEKALKKIRRKIKNKISAQESRRKKKEYMDSLEKKVESCSTENLELRKKVEVLENTNRTLLQQLQKLQTLVMGKVSRTCKLAGTQTGTCLMVVVLCFAVAFGSFFQGYGPYPSATKMALPSQHPLSEPYTASVVRSRNLLIYEEHAPLEESSSPASAGELGGWDRGSSLLRASSGLEALPEVDLPHFLISNETSLEKSVLLELQQHLVSSKLEGNETLKVVELERRVNATF", "length": 521 }, "evidence": [ { "id": "F1P1J2", "url": "https://omabrowser.org/oma/group/F1P1J2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "F1P1J2", "url": "https://www.uniprot.org/uniprotkb/F1P1J2" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "F1P1J2", "url": "https://www.uniprot.org/uniprotkb/F1P1J2" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1P1J2", "url": "https://www.uniprot.org/uniprotkb/F1P1J2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "F1P1J2", "url": "https://www.uniprot.org/uniprotkb/F1P1J2" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "F1P1J2", "url": "https://www.uniprot.org/uniprotkb/F1P1J2" } ], "pmid": "" }, { "name": "endoplasmic reticulum to Golgi vesicle-mediated transport", "id": "GO:0006888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006888", "evidence": [ { "database": "UniProtKB", "id": "F1P1J2", "url": "https://www.uniprot.org/uniprotkb/F1P1J2" } ], "pmid": "" }, { "name": "chondrocyte differentiation", "id": "GO:0002062", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002062", "evidence": [ { "database": "UniProtKB", "id": "F1P1J2", "url": "https://www.uniprot.org/uniprotkb/F1P1J2" } ], "pmid": "" }, { "name": "response to endoplasmic reticulum stress", "id": "GO:0034976", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034976", "evidence": [ { "database": "UniProtKB", "id": "F1P1J2", "url": "https://www.uniprot.org/uniprotkb/F1P1J2" } ], "pmid": "" }, { "name": "response to unfolded protein", "id": "GO:0006986", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006986", "evidence": [ { "database": "UniProtKB", "id": "F1P1J2", "url": "https://www.uniprot.org/uniprotkb/F1P1J2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "F1P1J2", "url": "https://www.uniprot.org/uniprotkb/F1P1J2" } ], "pmid": "" }, { "name": "DNA-binding transcription activator activity, RNA polymerase II-specific", "id": "GO:0001228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001228", "evidence": [ { "database": "UniProtKB", "id": "F1P1J2", "url": "https://www.uniprot.org/uniprotkb/F1P1J2" } ], "pmid": "" }, { "name": "cAMP response element binding", "id": "GO:0035497", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035497", "evidence": [ { "database": "UniProtKB", "id": "F1P1J2", "url": "https://www.uniprot.org/uniprotkb/F1P1J2" } ], "pmid": "" }, { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "F1P1J2", "url": "https://www.uniprot.org/uniprotkb/F1P1J2" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "F1P1J2", "url": "https://www.uniprot.org/uniprotkb/F1P1J2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 187, "end_pos": 189, "annotation": "n_glycosylation_sequon" }, { "start_pos": 325, "end_pos": 327, "annotation": "n_glycosylation_sequon" }, { "start_pos": 344, "end_pos": 346, "annotation": "n_glycosylation_sequon" }, { "start_pos": 480, "end_pos": 482, "annotation": "n_glycosylation_sequon" }, { "start_pos": 504, "end_pos": 506, "annotation": "n_glycosylation_sequon" }, { "start_pos": 517, "end_pos": 519, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1P1J2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P1J2" }, { "id": "PS50217", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50217" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "BZIP", "eco_id": "ECO_0000259", "start_pos": 291, "end_pos": 354, "start_aa": "Val", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 202 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 187, "end_pos": 189 }, { "start_pos": 325, "end_pos": 327 }, { "start_pos": 344, "end_pos": 346 }, { "start_pos": 480, "end_pos": 482 }, { "start_pos": 504, "end_pos": 506 }, { "start_pos": 517, "end_pos": 519 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], 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"count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YID4-1", "uniprot_ac": "A0A8V0YID4", "uniprot_id": "A0A8V0YID4_CHICK", "mass": { "chemical_mass": 78888.0, "monoisotopic_mass": 78888.0 }, "refseq": {}, "gene_names": [ { "name": "GNE", "type": "recommended", "evidence": [ { "id": "A0A8V0YID4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YID4" } ] } ], "protein_names": [ { "name": "Bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase", "type": "recommended", "evidence": [ { "id": "A0A8V0YID4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YID4/entry#names_and_taxonomy" } ] }, { "name": "2.7.1.60", "type": "synonym", "evidence": [ { "id": "A0A8V0YID4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YID4/entry#names_and_taxonomy" } ] }, { "name": "3.2.1.183", "type": "synonym", "evidence": [ { "id": "A0A8V0YID4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YID4/entry#names_and_taxonomy" } ] }, { "name": "UDP-GlcNAc-2-epimerase/ManAc kinase", "type": "synonym", "evidence": [ { "id": "A0A8V0YID4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YID4/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YID4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YID4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "GNE", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YID4", "locus": { "chromosome": "Z", "start_pos": 52737277, "end_pos": 52774520, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013225", "url": "https://www.ensembl.org/id/ENSGALG00010013225" } ] } } ], "crossref": [ { "id": "A0A8V0YID4", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YID4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000015331", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000015331", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd03786", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03786", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd24060", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd24060", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "427285", "url": "https://www.ncbi.nlm.nih.gov/gene/427285", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000600", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000600", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003331", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003331", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020004", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020004", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043129", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043129", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "HELYFKK", "url": "https://omabrowser.org/oma/group/HELYFKK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q3A578", "url": "https://www.orthodb.org/?gene=A0A3Q3A578", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YCR6", "url": "https://www.orthodb.org/?gene=A0A8V0YCR6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YCS9", "url": "https://www.orthodb.org/?gene=A0A8V0YCS9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YID4", "url": "https://www.orthodb.org/?gene=A0A8V0YID4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YL32", "url": "https://www.orthodb.org/?gene=A0A8V0YL32", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YL47", "url": "https://www.orthodb.org/?gene=A0A8V0YL47", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YR18", "url": "https://www.orthodb.org/?gene=A0A8V0YR18", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR18964", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR18964", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR18964:SF149", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR18964:SF149", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00480", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00480", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02350", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02350", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-4085001", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-4085001", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "23832", "url": "https://www.rhea-db.org/rhea/23832", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "30683", "url": "https://www.rhea-db.org/rhea/30683", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q3A578", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3A578", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q3A578-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3A578-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YCR6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCR6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YCR6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCR6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YCS9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCS9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YCS9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCS9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YID4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YID4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YID4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YID4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YL32", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL32", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YL32-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL32-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YL47", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL47", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YL47-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL47-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YR18", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YR18", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YR18-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YR18-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEKNGNNRKLRVCVATCNRADYSKLAPIMFGIKAEPQFFELDVVVLGSHLIDDYGNTYRMIEQDDFDIHTRLHTIVRGEDEAAMVESVGLALVKLPDVLNRLKPDIMIVHGDRFDALALATSAALMNIRILHIEGGEVSGTIDDSIRHAITKLAHYHVCCTRSAEQHLIAMCEDHDRILLAGCPSYDKLLSAKNKDYMSVIRMWLDVKPRDYIVALQHPVTTDIKHSIKMFELTLDALISFNKRTLVLFPNVDAGSKEMVRVMRKKGIEHHPNFRAVKHVPFDQFIQLVAHAGCMIGNSSCGVREVGAFGTPVINLGTRQTGRETGENVLHVRDADTQDKILHALQLQFGKQYPCSKIYGDGNAVPRILKFLKSIDLKEPLQKKFCFPPVKDNISQDIDHILETQSALAVDLGGTNLRVAIVSMKGEIVKKYTQLNPKTYEDRLGLILKMCVEAASEAVNLNCRILGVGISTGGRVNPREGIVLHSTKLIQEWSSVDLRTPISDALHLPVWVDNDGNCAALAERKFGHGKGIENFVTLITGTGIGGGIIHQHELIHGSSFCAAELGHIVVSLDGPECLCGSQGCIEAYASGIALQREAKKLHDEDLLLVEGMSMKNEEVVSAAHLIQAAKLGNAKAESILRTAGTALGLGVVNILHTMNPSLVILSGVLASHYVNAVKDVIHRQALSSVKTVDVVVSNLADPALLGAASLVLDYTTRRIY", "length": 720, "header": "tr|A0A8V0YID4-1|A0A8V0YID4_CHICK Isoform 1 of Bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase OS=Gallus gallus OX=9031 GN=GNE PE=1 SV=1 CANONICAL=A0A8V0YID4-1" }, "isoforms": [ { "isoform_ac": "A0A3Q3A578-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YID4/entry#A0A3Q3A578-1", "sequence": { "sequence": "MECLVPDPFLCKNFLYPSNTYRMIEQDDFDIHTRLHTIVRGEDEAAMVESVGLALVKLPDVLNRLKPDIMIVHGDRFDALALATSAALMNIRILHIEGGEVSGTIDDSIRHAITKLAHYHVCCTRSAEQHLIAMCEDHDRILLAGCPSYDKLLSAKNKDYMSVIRMWLGEDVKPRDYIVALQHPVTTDIKHSIKMFELTLDALISFNKRTLVLFPNVDAGSKEMVRVMRKKGIEHHPNFRAVKHVPFDQFIQLVAHAGCMIGNSSCGVREVGAFGTPVINLGTRQTGRETGENVLHVRDADTQDKILHALQLQFGKQYPCSKIYGDGNAVPRILKFLKSIDLKEPLQKKFCFPPVKDNISQDIDHILETQSALAVDLGGTNLRVAIVSMKGEIVKKYTQLNPKTYEDRLGLILKMCVEAASEAVNLNCRILGVGISTGGRVNPREGIVLHSTKLIQEWSSVDLRTPISDALHLPVWVDNDGNCAALAERKFGHGKGIENFVTLITGTGIGGGIIHQHELIHGSSFCAAELGHIVVSLDGPECLCGSQGCIEAYASGIALQREAKKLHDEDLLLVEGMSMKNEEVVSAAHLIQAAKLGNAKAESILRTAGTALGLGVVNILHTMNPSLVILSGVLASHYVNAVKDVIHRQALSSVKTVDVVVSNLADPALLGAASLVLDYTTRRIY", "length": 685, "header": "tr|A0A3Q3A578-1|A0A3Q3A578_CHICK Computationally mapped isoform of Bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase OS=Gallus gallus OX=9031 GN=GNE PE=1 SV=1 CANONICAL=A0A8V0YID4-1" }, "locus": { "chromosome": "Z", "start_pos": 52758423, "end_pos": 52739275, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031777.1", "url": "https://www.ensembl.org/id/ENSGALT00010031777.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018601.1", "url": "https://www.ensembl.org/id/ENSGALP00010018601.1" } ] } }, { "isoform_ac": "A0A8V0YCR6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YID4/entry#A0A8V0YCR6-1", "sequence": { "sequence": "MEKNGNNRKLRVCVATCNRADYSKLAPIMFGIKAEPQFFELDVVVLGSHLIDDYGNTYRMIEQDDFDIHTRLHTIVRGEDEAAMVESVGLALVKLPDVLNRLKPDIMIVHGDRFDALALATSAALMNIRILHIEGGEVSGTIDDSIRHAITKLAHYHVCCTRSAEQHLIAMCEDHDRILLAGCPSYDKLLSAKNKDYMSVIRMWLGSKEMVRVMRKKGIEHHPNFRAVKHVPFDQFIQLVAHAGCMIGNSSCGVREVGAFGTPVINLGTRQTGRETGENVLHVRDADTQDKILHALQLQFGKQYPCSKIYGDGNAVPRILKFLKSIDLKEPLQKKFCFPPVKDNISQDIDHILETQSALAVDLGGTNLRVAIVSMKGEIVKKYTQLNPKTYEDRLGLILKMCVEAASEAVNLNCRILGVGISTGGRVNPREGIVLHSTKLIQEWSSVDLRTPISDALHLPVWVDNDGNCAALAERKFGHGKGIENFVTLITGTGIGGGIIHQHELIHGSSFCAAELGHIVVSLDGPECLCGSQGCIEAYASGIALQREAKKLHDEDLLLVEGMSMKNEEVVSAAHLIQAAKLGNAKAESILRTAGTALGLGVVNILHTMNPSLVILSGVLASHYVNAVKDVIHRQALSSVKTVDVVVSNLADPALLGAASLVLDYTTRRIY", "length": 671, "header": "tr|A0A8V0YCR6-1|A0A8V0YID4_CHICK Computationally mapped isoform of Bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase OS=Gallus gallus OX=9031 GN=GNE PE=1 SV=1 CANONICAL=A0A8V0YID4-1" }, "locus": { "chromosome": "Z", "start_pos": 52759215, "end_pos": 52739275, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031765.1", "url": "https://www.ensembl.org/id/ENSGALT00010031765.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018592.1", "url": "https://www.ensembl.org/id/ENSGALP00010018592.1" } ] } }, { "isoform_ac": "A0A8V0YCS9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YID4/entry#A0A8V0YCS9-1", "sequence": { "sequence": "MPLAFLDTWAHCWLMFHRLLTRTLRSFSARELFSHCSASLRGVVFTHNQDLELYFKNLSKQKQKEDMEKNGNNRKLRVCVATCNRADYSKLAPIMFGIKAEPQFFELDVVVLGSHLIDDYGNTYRMIEQDDFDIHTRLHTIVRGEDEAAMVESVGLALVKLPDVLNRLKPDIMIVHGDRFDALALATSAALMNIRILHIEGGEVSGTIDDSIRHAITKLAHYHVCCTRSAEQHLIAMCEDHDRILLAGCPSYDKLLSAKNKDYMSVIRMWLGEDVKPRDYIVALQHPVTTDIKHSIKMFELTLDALISFNKRTLVLFPNVDAGSKEMVRVMRKKGIEHHPNFRAVKHVPFDQFIQLVAHAGCMIGNSSCGVREVGAFGTPVINLGTRQTGRETGENVLHVRDADTQDKILHALQLQFGKQYPCSKIYGDGNAVPRILKFLKSIDLKEPLQKKFCFPPVKDNISQDIDHILETQSALAVDLGGTNLRVAIVSMKGEIVKKYTQLNPKTYEDRLGLILKMCVEAASEAVNLNCRILGVGISTGGRVNPREGIVLHSTKLIQEWSSVDLRTPISDALHLPVWVDNDGNCAALAERKFGHGKGIENFVTLITGTGIGGGIIHQHELIHGSSFCAAELGHIVVSLDGPECLCGSQGCIEAYASGIALQREAKKLHDEDLLLVEGMSMKNEEVVSAAHLIQAAKLGNAKAESILRTAGTALGLGVVNILHTMNPSLVILSGVLASHYVNAVKDVIHRQALSSVKTVDVVVSNLADPALLGAASLVLDYTTRRIY", "length": 788, "header": "tr|A0A8V0YCS9-1|A0A8V0YID4_CHICK Computationally mapped isoform of Bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase OS=Gallus gallus OX=9031 GN=GNE PE=1 SV=1 CANONICAL=A0A8V0YID4-1" }, "locus": { "chromosome": "Z", "start_pos": 52761847, "end_pos": 52739275, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031781.1", "url": "https://www.ensembl.org/id/ENSGALT00010031781.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018602.1", "url": "https://www.ensembl.org/id/ENSGALP00010018602.1" } ] } }, { "isoform_ac": "A0A8V0YID4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YID4/entry#A0A8V0YID4-1", "sequence": { "sequence": "MEKNGNNRKLRVCVATCNRADYSKLAPIMFGIKAEPQFFELDVVVLGSHLIDDYGNTYRMIEQDDFDIHTRLHTIVRGEDEAAMVESVGLALVKLPDVLNRLKPDIMIVHGDRFDALALATSAALMNIRILHIEGGEVSGTIDDSIRHAITKLAHYHVCCTRSAEQHLIAMCEDHDRILLAGCPSYDKLLSAKNKDYMSVIRMWLDVKPRDYIVALQHPVTTDIKHSIKMFELTLDALISFNKRTLVLFPNVDAGSKEMVRVMRKKGIEHHPNFRAVKHVPFDQFIQLVAHAGCMIGNSSCGVREVGAFGTPVINLGTRQTGRETGENVLHVRDADTQDKILHALQLQFGKQYPCSKIYGDGNAVPRILKFLKSIDLKEPLQKKFCFPPVKDNISQDIDHILETQSALAVDLGGTNLRVAIVSMKGEIVKKYTQLNPKTYEDRLGLILKMCVEAASEAVNLNCRILGVGISTGGRVNPREGIVLHSTKLIQEWSSVDLRTPISDALHLPVWVDNDGNCAALAERKFGHGKGIENFVTLITGTGIGGGIIHQHELIHGSSFCAAELGHIVVSLDGPECLCGSQGCIEAYASGIALQREAKKLHDEDLLLVEGMSMKNEEVVSAAHLIQAAKLGNAKAESILRTAGTALGLGVVNILHTMNPSLVILSGVLASHYVNAVKDVIHRQALSSVKTVDVVVSNLADPALLGAASLVLDYTTRRIY", "length": 720, "header": "tr|A0A8V0YID4-1|A0A8V0YID4_CHICK Isoform 1 of Bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase OS=Gallus gallus OX=9031 GN=GNE PE=1 SV=1 CANONICAL=A0A8V0YID4-1" }, "locus": { "chromosome": "Z", "start_pos": 52759215, "end_pos": 52739275, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031772.1", "url": "https://www.ensembl.org/id/ENSGALT00010031772.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018596.1", "url": "https://www.ensembl.org/id/ENSGALP00010018596.1" } ] } }, { "isoform_ac": "A0A8V0YL32-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YID4/entry#A0A8V0YL32-1", "sequence": { "sequence": "MEKNGNNRKLRVCVATCNRADYSKLAPIMFGIKAEPQFFELDVVVLGSHLIDDYGNTYRMIEQDDFDIHTRLHTIVRGEDEAAMVESVGLALVKLPDVLNRLKPDIMIVHGDRFDALALATSAALMNIRILHIEGGEVSGTIDDSIRHAITKLAHYHVCCTRSAEQHLIAMCEDHDRILLAGCPSYDKLLSAKNKDYMSVIRMWLGEDVKPRDYIVALQHPVTTDIKHSIKMFELTLDALISFNKRTLVLFPNVDAGSKEMVRVMRKKGIEHHPNFRAVKHVPFDQFIQLVAHAGCMIGNSSCGVREVGAFGTPVINLGTRQTGRETGENVLHVRDADTQDKILHALQLQFGKQYPCSKIYGDGNAVPRILKFLKSIDLKEPLQKKFCFPPVKDNISQDIDHILETQSALAVDLGGTNLRVAIVSMKGEIVKKYTQLNPKTYEDRLGLILKMCVEAASEAVNLNCRILGVGISTGGRVNPREGIVLHSTKLIQEWSSVDLRTPISDALHLPVWVDNDGNCAALAERKFGHGKGIENFVTLITGTGIGGGIIHQHELIHGSSFCAAELGHIVVSLDGPECLCGSQGCIEAYASGIALQREAKKLHDEDLLLVEGMSMKNEEVVSAAHLIQAAKLGNAKAESILRTAGTALGLGVVNILHTMNPSLVILSGVLASHYVNAVKDVIHRQALSSVKTVDVVVSNLADPALLGAASLVLDYTTRRIY", "length": 722, "header": "tr|A0A8V0YL32-1|A0A8V0YL32_CHICK Computationally mapped isoform of Bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase OS=Gallus gallus OX=9031 GN=GNE PE=1 SV=1 CANONICAL=A0A8V0YID4-1" }, "locus": { "chromosome": "Z", "start_pos": 52759215, "end_pos": 52739275, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031761.1", "url": "https://www.ensembl.org/id/ENSGALT00010031761.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018589.1", "url": "https://www.ensembl.org/id/ENSGALP00010018589.1" } ] } }, { "isoform_ac": "A0A8V0YL47-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YID4/entry#A0A8V0YL47-1", "sequence": { "sequence": "MSNAWRQVFSQLHHGHSLPVKPTAWKSIQALLAESRAAADRRALGPRPHRGRGYYAHCRCRELYFKNLSKQKQKEDMEKNGNNRKLRVCVATCNRADYSKLAPIMFGIKAEPQFFELDVVVLGSHLIDDYGNTYRMIEQDDFDIHTRLHTIVRGEDEAAMVESVGLALVKLPDVLNRLKPDIMIVHGDRFDALALATSAALMNIRILHIEGGEVSGTIDDSIRHAITKLAHYHVCCTRSAEQHLIAMCEDHDRILLAGCPSYDKLLSAKNKDYMSVIRMWLGEDVKPRDYIVALQHPVTTDIKHSIKMFELTLDALISFNKRTLVLFPNVDAGSKEMVRVMRKKGIEHHPNFRAVKHVPFDQFIQLVAHAGCMIGNSSCGVREVGAFGTPVINLGTRQTGRETGENVLHVRDADTQDKILHALQLQFGKQYPCSKIYGDGNAVPRILKFLKSIDLKEPLQKKFCFPPVKDNISQDIDHILETQSALAVDLGGTNLRVAIVSMKGEIVKKYTQLNPKTYEDRLGLILKMCVEAASEAVNLNCRILGVGISTGGRVNPREGIVLHSTKLIQEWSSVDLRTPISDALHLPVWVDNDGNCAALAERKFGHGKGIENFVTLITGTGIGGGIIHQHELIHGSSFCAAELGHIVVSLDGPECLCGSQGCIEAYASGIALQREAKKLHDEDLLLVEGMSMKNEEVVSAAHLIQAAKLGNAKAESILRTAGTALGLGVVNILHTMNPSLVILSGVLASHYVNAVKDVIHRQALSSVKTVDVVVSNLADPALLGAASLVLDYTTRRIY", "length": 798, "header": "tr|A0A8V0YL47-1|A0A8V0YL47_CHICK Computationally mapped isoform of Bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase OS=Gallus gallus OX=9031 GN=GNE PE=1 SV=1 CANONICAL=A0A8V0YID4-1" }, "locus": { "chromosome": "Z", "start_pos": 52765522, "end_pos": 52739275, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031784.1", "url": "https://www.ensembl.org/id/ENSGALT00010031784.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018605.1", "url": "https://www.ensembl.org/id/ENSGALP00010018605.1" } ] } }, { "isoform_ac": "A0A8V0YR18-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YID4/entry#A0A8V0YR18-1", "sequence": { "sequence": "MGTNVPPRREPPAQGPHELYFKNLSKQKQKEDMEKNGNNRKLRVCVATCNRADYSKLAPIMFGIKAEPQFFELDVVVLGSHLIDDYGNTYRMIEQDDFDIHTRLHTIVRGEDEAAMVESVGLALVKLPDVLNRLKPDIMIVHGDRFDALALATSAALMNIRILHIEGGEVSGTIDDSIRHAITKLAHYHVCCTRSAEQHLIAMCEDHDRILLAGCPSYDKLLSAKNKDYMSVIRMWLGEDVKPRDYIVALQHPVTTDIKHSIKMFELTLDALISFNKRTLVLFPNVDAGSKEMVRVMRKKGIEHHPNFRAVKHVPFDQFIQLVAHAGCMIGNSSCGVREVGAFGTPVINLGTRQTGRETGENVLHVRDADTQDKILHALQLQFGKQYPCSKIYGDGNAVPRILKFLKSIDLKEPLQKKFCFPPVKDNISQDIDHILETQSALAVDLGGTNLRVAIVSMKGEIVKKYTQLNPKTYEDRLGLILKMCVEAASEAVNLNCRILGVGISTGGRVNPREGIVLHSTKLIQEWSSVDLRTPISDALHLPVWVDNDGNCAALAERKFGHGKGIENFVTLITGTGGIIHQHELIHGSSFCAAELGHIVVSLDGPECLCGSQGCIEAYASGIALQREAKKLHDEDLLLVEGMSMKNEEVVSAAHLIQAAKLGNAKAESILRTAGTALGLGVVNILHTMNPSLVILSGVLASHYVNAVKDVIHRQALSSVKTVDVVVSNLADPALLGAASLVLDYTTRRIY", "length": 751, "header": "tr|A0A8V0YR18-1|A0A8V0YR18_CHICK Computationally mapped isoform of Bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase OS=Gallus gallus OX=9031 GN=GNE PE=1 SV=1 CANONICAL=A0A8V0YID4-1" }, "locus": { "chromosome": "Z", "start_pos": 52774425, "end_pos": 52739275, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031788.1", "url": "https://www.ensembl.org/id/ENSGALT00010031788.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018608.1", "url": "https://www.ensembl.org/id/ENSGALP00010018608.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "R-GGA-4085001", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-4085001", "resource": "Reactome", "description": "Sialic acid metabolism" } ], "orthologs": [ { "uniprot_canonical_ac": "F1MIL9-1", "protein_name": "Bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase", "gene_name": "GNE", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MEKKENNRKLRVCVATCNRADYSKLAPIMFGIKMEPEFFELDVVVLGSHLIDDYGNTYRMIEQDDFDINTRLHTIVRGEDEAAMVESVGLALVKLPDVLNRLKPDIMIVHGDRFDALALATSAALMNIRILHIEGGEVSGTIDDSIRHAITKLAHYHVCCTRSAEQHLISMCEDHDRILLAGCPSYDKLLSAKNKDYMSIIRMWLGDDVKPKDYIVALQHPVTTDIKHSIKMFELTLDALISFNKRTLVLFPNIDAGSKEMVRVMRKKGIEHHPNFRAVKHVPFDQFIQLVAHAGCMIGNSSCGVREVGAFGTPVINLGTRQIGRETGENVLHVRDADTQDKILQALHLQFGKQYPCSKIYGDGNAVPRILKFLKSIDLQEPLQKKFCFPPVKDNISQDIDHILETLSALAVDLGGTNLRVAIVSMKGEIVKKYTQFNPKTYEERINLILQMCVEAAAEAVKLNCRILGVGISTGGRVNPREGIVLHSTKLIQEWNSVDLRSPLSDTLHLPVWVDNDGNCAALAERKFGQGKGLENFVTLITGTGIGGGIVHQHELIHGSSFCAAELGHIVVSLDGPDCSCGSHGCIEAYASGMALQREAKKLHDEDQLLVEGMSVPKDEAVGALHLIQAAKLGNAKAQSILRTAGTALGLGVVNILHTMNPSLVILSGILASHYIHTVKDVIRQQALSSVQDVDVVVSDLVEPALLGAASMVLDYTTRRIY", "length": 722 }, "evidence": [ { "id": "A0A8V0YID4", "url": "https://omabrowser.org/oma/group/A0A8V0YID4/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "O35826-1", "protein_name": "Bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase", "gene_name": "Gne", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEKNGNNRKLRVCVATCNRADYSKLAPIMFGIKTEPAFFELDVVVLGSHLIDDYGNTYRMIEQDDFDINTRLHTIVRGEDEAAMVESVGLALVKLPDVLNRLKPDIMIVHGDRFDALALATSAALMNIRILHIEGGEVSGTIDDSIRHAITKLAHYHVCCTRSAEQHLISMCEDHDRILLAGCPSYDKLLSAKNKDYMSIIRMWLGDDVKCKDYIVALQHPVTTDIKHSIKMFELTLDALISFNKRTLVLFPNIDAGSKEMVRVMRKKGIEHHPNFRAVKHVPFDQFIQLVAHAGCMIGNSSCGVREVGAFGTPVINLGTRQIGRETGENVLHVRDADTQDKILQALHLQFGKQYPCSKIYGDGNAVPRILKFLKSIDLQEPLQKKFCFPPVKENISQDIDHILETLSALAVDLGGTNLRVAIVSMKGEIVKKYTQFNPKTYEERISLILQMCVEAAAEAVKLNCRILGVGISTGGRVNPQEGVVLHSTKLIQEWNSVDLRTPLSDTLHLPVWVDNDGNCAAMAERKFGQGKGQENFVTLITGTGIGGGIIHQHELIHGSSFCAAELGHLVVSLDGPDCSCGSHGCIEAYASGMALQREAKKLHDEDLLLVEGMSVPKDEAVGALHLIQAAKLGNVKAQSILRTAGTALGLGVVNILHTMNPSLVILSGVLASHYIHIVRDVIRQQALSSVQDVDVVVSDLVDPALLGAASMVLDYTTRRIH", "length": 722 }, "evidence": [ { "id": "A0A8V0YID4", "url": "https://omabrowser.org/oma/group/A0A8V0YID4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q91WG8-1", "protein_name": "Bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase", "gene_name": "Gne", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEKNGNNRKLRVCVATCNRADYSKLAPIMFGIKTEPAFFELDVVVLGSHLIDDYGNTYRMIEQDDFDINTRLHTIVRGEDEAAMVESVGLALVKLPDVLNRLKPDIMIVHGDRFDALALATSAALMNIRILHIEGGEVSGTIDDSIRHAITKLAHYHVCCTRSAEQHLISMCEDHDRILLAGCPSYDKLLSAKNKDYMSIIRMWLGDDVKCKDYIVALQHPVTTDIKHSIKMFELTLDALISFNKRTLVLFPNIDAGSKEMVRVMRKKGIEHHPNFRAVKHVPFDQFIQLVAHAGCMIGNSSCGVREVGAFGTPVINLGTRQIGRETGENVLHVRDADTQDKILQALHLQFGKQYPCSKIYGDGNAVPRILKFLKSIDLQEPLQKKFCFPPVKENISQDIDHILETLSALAVDLGGTNLRVAIVSMKGEIVKKYTQFNPKTYEERISLILQMCVEAAAEAVKLNCRILGVGISTGGRVNPQEGVVLHSTKLIQEWNSVDLRTPLSDTLHLPVWVDNDGNCAAMAERKFGQGKGQENFVTLITGTGIGGGIIHQHELIHGSSFCAAELGHLVVSLDGPDCSCGSHGCIEAYASGMALQREAKKLHDEDLLLVEGMSVPKDEAVGALHLIQAAKLGNVKAQSILRTAGTALGLGVVNILHTMNPSLVILSGVLASHYIHIVKDVIRQQALSSVQDVDVVVSDLVDPALLGAASMVLDYTTRRIH", "length": 722 }, "evidence": [ { "id": "A0A8V0YID4", "url": "https://omabrowser.org/oma/group/A0A8V0YID4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9Y223-1", "protein_name": "Bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase", "gene_name": "GNE", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEKNGNNRKLRVCVATCNRADYSKLAPIMFGIKTEPEFFELDVVVLGSHLIDDYGNTYRMIEQDDFDINTRLHTIVRGEDEAAMVESVGLALVKLPDVLNRLKPDIMIVHGDRFDALALATSAALMNIRILHIEGGEVSGTIDDSIRHAITKLAHYHVCCTRSAEQHLISMCEDHDRILLAGCPSYDKLLSAKNKDYMSIIRMWLGDDVKSKDYIVALQHPVTTDIKHSIKMFELTLDALISFNKRTLVLFPNIDAGSKEMVRVMRKKGIEHHPNFRAVKHVPFDQFIQLVAHAGCMIGNSSCGVREVGAFGTPVINLGTRQIGRETGENVLHVRDADTQDKILQALHLQFGKQYPCSKIYGDGNAVPRILKFLKSIDLQEPLQKKFCFPPVKENISQDIDHILETLSALAVDLGGTNLRVAIVSMKGEIVKKYTQFNPKTYEERINLILQMCVEAAAEAVKLNCRILGVGISTGGRVNPREGIVLHSTKLIQEWNSVDLRTPLSDTLHLPVWVDNDGNCAALAERKFGQGKGLENFVTLITGTGIGGGIIHQHELIHGSSFCAAELGHLVVSLDGPDCSCGSHGCIEAYASGMALQREAKKLHDEDLLLVEGMSVPKDEAVGALHLIQAAKLGNAKAQSILRTAGTALGLGVVNILHTMNPSLVILSGVLASHYIHIVKDVIRQQALSSVQDVDVVVSDLVDPALLGAASMVLDYTTRRIY", "length": 722 }, "evidence": [ { "id": "A0A8V0YID4", "url": "https://omabrowser.org/oma/group/A0A8V0YID4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "UDP-N-acetylglucosamine 2-epimerase activity", "id": "GO:0008761", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008761", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YID4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YID4" } ], "pmid": "" }, { "name": "N-acylmannosamine kinase activity", "id": "GO:0009384", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009384", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YID4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YID4" } ], "pmid": "" }, { "name": "hydrolase activity, hydrolyzing O-glycosyl compounds", "id": "GO:0004553", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004553", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YID4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YID4" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YID4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YID4" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YID4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YID4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YID4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YID4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "UDP-N-acetylglucosamine metabolic process", "id": "GO:0006047", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006047", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YID4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YID4" } ], "pmid": "" }, { "name": "CMP-N-acetylneuraminate biosynthetic process", "id": "GO:0006055", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006055", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YID4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YID4" } ], "pmid": "" }, { "name": "N-acetylneuraminate biosynthetic process", "id": "GO:0046380", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046380", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YID4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YID4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 298, "end_pos": 300, "annotation": "n_glycosylation_sequon" }, { "start_pos": 393, "end_pos": 395, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "23832", "name": "", "equation": "an N-acyl-D-mannosamine + ATP = an N-acyl-D-mannosamine 6-phosphate + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YID4-1" ], "evidence": [ { "id": "23832", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/23832" } ] }, { "id": "30683", "name": "", "equation": "UDP-N-acetyl-alpha-D-glucosamine + H2O = aldehydo-N-acetyl-D-mannosamine + UDP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YID4-1" ], "evidence": [ { "id": "30683", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/30683" } ] }, { "id": "R-GGA-4085021", "name": "GNE hydrolyzes and epimerises UDP-GlcNAc to ManNAc and UDP", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YID4-1" ], "evidence": [ { "id": "R-GGA-4085021", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-4085021" } ] }, { "id": "R-GGA-4085028", "name": "GNE phosphorylates ManNAc to ManNAc-6-P", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [ "R-ALL-4085214" ], "output_participant_list": [ "R-ALL-4085225" ], "enzyme_list": [ "A0A8V0YID4-1" ], "evidence": [ { "id": "R-GGA-4085028", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-4085028" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-4085214", "participant_name": "ManNAc [cytosol]", "crossref": [ { "id": "17122", "database": "ChEBI", "url": "" }, { "id": "C00645", "database": "COMPOUND", "url": "" }, { "id": "ZINC000013532465", "database": "ZINC", "url": "" } ] }, { "participant_id": "R-ALL-4085225", "participant_name": "ManNAc-6-P [cytosol]", "crossref": [ { "id": "58557", "database": "ChEBI", "url": "" }, { "id": "ZINC000034997269", "database": "ZINC", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A0A8V0YID4", "gene_name": "GNE", "activity": [ { "ec_number": "2.7.1.60", "activity": 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"field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YG75-1", "uniprot_ac": "A0A8V0YG75", "uniprot_id": "A0A8V0YG75_CHICK", "mass": { "chemical_mass": 117834.0, "monoisotopic_mass": 117834.0 }, "refseq": { "ac": "XP_416077", "name": "DNA helicase B isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_416077" }, "gene_names": [ { "name": "HELB", "type": "recommended", "evidence": [ { "id": "A0A8V0YG75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG75" } ] }, { "name": "HELB", "type": "synonym", "evidence": [ { "id": "XP_416077", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_416077" } ] } ], "protein_names": [ { "name": "DNA helicase B", "type": "recommended", "evidence": [ { "id": "A0A8V0YG75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG75/entry#names_and_taxonomy" } ] }, { "name": "3.6.4.12", "type": "synonym", "evidence": [ { "id": "A0A8V0YG75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG75/entry#names_and_taxonomy" } ] }, { "name": "DNA helicase B isoform X1", "type": "synonym", "evidence": [ { "id": "XP_416077", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_416077" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_416077.3. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_416077", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_416077" } ] }, { "annotation": "5'-3' DNA helicase involved in DNA damage response by acting as an inhibitor of DNA end resection. Recruitment to single-stranded DNA (ssDNA) following DNA damage leads to inhibit the nucleases catalyzing resection, such as EXO1, BLM and DNA2, possibly via the 5'-3' ssDNA translocase activity of HELB. As cells approach S phase, DNA end resection is promoted by the nuclear export of HELB following phosphorylation. Acts independently of TP53BP1. Unwinds duplex DNA with 5'-3' polarity. Has single-strand DNA-dependent ATPase and DNA helicase activities. Prefers ATP and dATP as substrates. During S phase, may facilitate cellular recovery from replication stress.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YG75", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG75#function" }, { "database": "UniProtKB", "id": "ARBA00055511", "url": "https://www.uniprot.org/uniprotkb/ARBA00055511#function" }, { "database": "UniProtKB", "id": "A0A8V0YCT0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCT0#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YG75", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG75" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "HELB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG75", "locus": { "chromosome": "1", "start_pos": 34557233, "end_pos": 34542887, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012090", "url": "https://www.ensembl.org/id/ENSGALG00010012090" } ] } } ], "crossref": [ { "id": "A0A8V0YG75", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YG75", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd17933", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd17933", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd18809", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18809", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "417836", "url": "https://www.ncbi.nlm.nih.gov/gene/417836", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050534", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050534", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR058839", "url": "https://www.ebi.ac.uk/interpro/entry/IPR058839", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "KIKHAWA", "url": "https://omabrowser.org/oma/group/KIKHAWA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YCT0", "url": "https://www.orthodb.org/?gene=A0A8V0YCT0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YG75", "url": "https://www.orthodb.org/?gene=A0A8V0YG75", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR43788", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43788", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR43788:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43788:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13604", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13604", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25894", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25894", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_416077", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_416077", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YCT0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCT0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YCT0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCT0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YG75", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG75", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YG75-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG75-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAGTGRGAAAELWGVLLPPRRAAEGSEDEEDEEVEEEPHLAEAALLEASGRDLTAALPPRRAAVIQESSKKEYEVVGRFPLVGPWWTVNVKVKKGGSKYFVQGYPSYFLRTDIEDNNREIFSLFLKECGVPEYFKKLFFAWLPAKSTLSFGNLEEKLKQFQVSHLSTGKKQGDTKDFNISYYVWKSVAGKAVLVALTYPMILEFLPTLLPRHFCSLLDTVCWQRKTESADTDGETVHFEDEILTKLDEILKNEPWKLGFSRITYRELKLSYCEATWDAFRQCEHLLWKIPDLQKNALILYNKLKKHCREMGHTYENQDELTRFVSEDMSIESAWQSLEFLKDENIVIREKTLVFLPHLYKSEKDIAMYIGDLLSKCSWQLDVDARKILTASEMSREVVDSKTNGIQAQEVEHLKEDNPHNHHCENQFPEREVASTSGTQSKAEVDPDQVIAIEKICSNPVTIISGKGGCGKSTIVSCLFRHLKQIEKEVEAASKDFEEDLDVSEEWDTFDRHWESENTCTKNPLNVLFTAPTGRAASLLSEKTNLPAYTLHQIIYSFKSWRQTEKEVPWKFSTVTVLIVDEGSLVSVHILSLVLKILCEHAQLAKLIILGDTRQLPSIDPGNMLADIFNSLKSKGLSVELRTNHRAESQLIVDNATRISLRKLPEFDEVLKFSGWNKELAMPSPEKKFIFIALPSNGGADNLQAAIKALLKEGPGLQDATQSQFIAFRRQDCDLINELCCQHYSNHLTRDHKRRLLFQVDDKISCTRNMYLKDLLPDPGIGRDPEQHKCRNGETTLSTENTEEGKRLCNGDIFFITRDVEINKQRLLTISSTYGSTYTVNYKALKKLCHIKHAWARTIHTFQGSEEKTVVYVVGNPGRQHWQHVYTAVTRGRCRVYVIAEEMHLRKAVTNNNFPRKTRLQRFLREAIANTNSCLTQTSSPLTKSWPGQERGTQPVSLTRDVPDPSQPGTDRIQQEGSADLNKEHTGHLQQISPYKRQQSHAEDSENPLGKDSPLGTARLRSLTLEQVTPRKLFKS", "length": 1035, "header": "tr|A0A8V0YG75-1|A0A8V0YG75_CHICK Isoform 1 of DNA helicase B OS=Gallus gallus OX=9031 GN=HELB PE=3 SV=1 CANONICAL=A0A8V0YG75-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YCT0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG75/entry#A0A8V0YCT0-1", "sequence": { "sequence": "MARDFPLPCKEPWSFSSAELQRAQRSALKMKAKPEPPYNLGRHTAVIQESSKKEYEVVGRFPLVGPWWTVNVKVKKGGSKYFVQGYPSYFLRTDIEDNNREIFSLFLKECGVPEYFKKLFFAWLPAKSTLSFGNLEEKLKQFQVSHLSTGKKQGDTKDFNISYYVWKSVAGKAVLVALTYPMILEFLPTLLPRHFCSLLDTVCWQRKTESADTDGETVHFEDEILTKLDEILKNEPWKLGFSRITYRELKLSYCEATWDAFRQCEHLLWKIPDLQKNALILYNKLKKHCREMGHTYENQDELTRFVSEDMSIESAWQSLEFLKDENIVIREKTLVFLPHLYKSEKDIAMYIGDLLSKCSWQLDVDARKILTASEMSREVVDSKTNGIQAQEVEHLKEDNPHNHHCENQFPEREVASTSGTQSKAEVDPDQVIAIEKICSNPVTIISGKGGCGKSTIVSCLFRHLKQIEKEVEAASKDFEEDLDVSEEWDTFDRHWESENTCTKNPLNVLFTAPTGRAASLLSEKTNLPAYTLHQIIYSFKSWRQTEKEVPWKFSTVTVLIVDEGSLVSVHILSLVLKILCEHAQLAKLIILGDTRQLPSIDPGNMLADIFNSLKSKGLSVELRTNHRAESQLIVDNATRISLRKLPEFDEVLKFSGWNKELAMPSPEKKFIFIALPSNGGADNLQAAIKALLKEGPGLQDATQSQFIAFRRQDCDLINELCCQHYSNHLTRDHKRRLLFQVDDKISCTRNMYLKDLLPDPGIGRDPEQHKCRNGETTLSTENTEEGKRLCNGDIFFITRDVEINKQRLLTISSTYGSTYTVNYKALKKLCHIKHAWARTIHTFQGSEEKTVVYVVGNPGRQHWQHVYTAVTRGRCRVYVIAEEMHLRKAVTNNNFPRKTRLQRFLREAIANTNSCLTQTSSPLTKSWPGQERGTQPVSLTRDVPDPSQPGTDRIQQEGSADLNKEHTGHLQQISPYKRQQSHAEDSENPLGKDSPLGTARLRSLTLEQVTPRKLFKS", "length": 1017, "header": "tr|A0A8V0YCT0-1|A0A8V0YG75_CHICK Computationally mapped isoform of DNA helicase B OS=Gallus gallus OX=9031 GN=HELB PE=3 SV=1 CANONICAL=A0A8V0YG75-1" }, "locus": { "chromosome": "1", "start_pos": 34556232, "end_pos": 34542949, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028977.1", "url": "https://www.ensembl.org/id/ENSGALT00010028977.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016736.1", "url": "https://www.ensembl.org/id/ENSGALP00010016736.1" } ] } }, { "isoform_ac": "A0A8V0YG75-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG75/entry#A0A8V0YG75-1", "sequence": { "sequence": "MAGTGRGAAAELWGVLLPPRRAAEGSEDEEDEEVEEEPHLAEAALLEASGRDLTAALPPRRAAVIQESSKKEYEVVGRFPLVGPWWTVNVKVKKGGSKYFVQGYPSYFLRTDIEDNNREIFSLFLKECGVPEYFKKLFFAWLPAKSTLSFGNLEEKLKQFQVSHLSTGKKQGDTKDFNISYYVWKSVAGKAVLVALTYPMILEFLPTLLPRHFCSLLDTVCWQRKTESADTDGETVHFEDEILTKLDEILKNEPWKLGFSRITYRELKLSYCEATWDAFRQCEHLLWKIPDLQKNALILYNKLKKHCREMGHTYENQDELTRFVSEDMSIESAWQSLEFLKDENIVIREKTLVFLPHLYKSEKDIAMYIGDLLSKCSWQLDVDARKILTASEMSREVVDSKTNGIQAQEVEHLKEDNPHNHHCENQFPEREVASTSGTQSKAEVDPDQVIAIEKICSNPVTIISGKGGCGKSTIVSCLFRHLKQIEKEVEAASKDFEEDLDVSEEWDTFDRHWESENTCTKNPLNVLFTAPTGRAASLLSEKTNLPAYTLHQIIYSFKSWRQTEKEVPWKFSTVTVLIVDEGSLVSVHILSLVLKILCEHAQLAKLIILGDTRQLPSIDPGNMLADIFNSLKSKGLSVELRTNHRAESQLIVDNATRISLRKLPEFDEVLKFSGWNKELAMPSPEKKFIFIALPSNGGADNLQAAIKALLKEGPGLQDATQSQFIAFRRQDCDLINELCCQHYSNHLTRDHKRRLLFQVDDKISCTRNMYLKDLLPDPGIGRDPEQHKCRNGETTLSTENTEEGKRLCNGDIFFITRDVEINKQRLLTISSTYGSTYTVNYKALKKLCHIKHAWARTIHTFQGSEEKTVVYVVGNPGRQHWQHVYTAVTRGRCRVYVIAEEMHLRKAVTNNNFPRKTRLQRFLREAIANTNSCLTQTSSPLTKSWPGQERGTQPVSLTRDVPDPSQPGTDRIQQEGSADLNKEHTGHLQQISPYKRQQSHAEDSENPLGKDSPLGTARLRSLTLEQVTPRKLFKS", "length": 1035, "header": "tr|A0A8V0YG75-1|A0A8V0YG75_CHICK Isoform 1 of DNA helicase B OS=Gallus gallus OX=9031 GN=HELB PE=3 SV=1 CANONICAL=A0A8V0YG75-1" }, "locus": { "chromosome": "1", "start_pos": 34556232, "end_pos": 34543292, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028971.1", "url": "https://www.ensembl.org/id/ENSGALT00010028971.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016730.1", "url": "https://www.ensembl.org/id/ENSGALP00010016730.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 889, "start_aa": "Thr", "end_pos": 889, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr889", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "B0UYS3-1", "protein_name": "DNA helicase B", "gene_name": "helb", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MALQSPIAGLKTITGYILPEEQAVQPNKDDGLESEDEEEEGQPEFLDMKEMNSVSSGGNMFKSLVPTSKEVSILVGKKTYKVEGRFPLCDPWWEVTCTIRLGRLKAFVKGYPFYRLRTHLKSEGRSLLSLFLTACKAQADHVKMFMDWLPTDRRVELVNVLDVLQEFEDSSLEHEAVAQQLKSSVNCSVVWTHVKAASLYPGIMKYLPTLLPGQYLDIIKRARIEDIPETSAMDEDPQNEQRKTNVLSKLEELINTNNVWKLGFNYIMFKELHLIRCEAKLEAFKLCDLFSAIPLLQRNALILYAELKKHCRVTGSTYITQEMLVDKIFSETGADGAWAALHFLVTQGVLMKESTKVALRNLLKYEKGIAECLTGLVQGDPWKIHLDVKEVLREAQIKRLRAKACEKHNATMKSKDDANTSASAAENSTAVFEQLGIDLDQPGTSSMVHNGETPSCDDSENTTLTIKEENLTSDSDSDLDIDPSTIELDCDQVRAAEMMCANPVTVISGKGGCGKTTVVSLVFKAAMEQQTSDLEEVQKACEDFQNDSHGSSNGLALDVHEEKNHSEKSISNEKSVEVLLTAPTGRAASLLTKRTGFTAYTMHQVLWSFMTVDKDRSGNPQDWKFSKVRVLVVDEGSLVSVQILHSILSMLTKHAQLQKFIILGDVRQLPSIEPGNTLYDLFEGLRRVRWAIEMRTNHRAESELIVRNAGLISEMGKKKYYKPLDFDATIDMTNPSAVPSDKRFIFIKISSDNFSFDLQEAILFLLKEAPGLKDHILSQFVAFRRKDCELINELCCRHYSNHTTKTAKKTFNFQVGDKVCCTKNGYVTDYDKKETSLADIRASHNRAESQQDDQKKEKKEKKERLCNGEIFFIKDDVTKSVENEKNKMVRQLTLDDKSDRQVTCNYKELQRECKLRHSWARTIHTFQGSEAETIVYILGDSPAQNWQHVYTAVTRGQKRVYVVGTEYDLEGAIRKRITPRNTRLCGFVNTKVGQQDPLTTSASTQRQAETTLNHSFGHSQSTPVASQTPIRPQMLSSTRPSCARNLYTDKNGEGDQTSNISLQDDMAFSQAYSWSPMDSCDEAGRVQNENMTELSNHVDDALLATLSSSPNESSRGSKRTIAEDIYSTPSKLPKQTASEESPMVSSRLNLLSLSSPDIKSSRQLFQDDTHSHRGQP", "length": 1176 }, "evidence": [ { "id": "A0A8V0YG75", "url": "https://omabrowser.org/oma/group/A0A8V0YG75/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "D4AAN8-1", "protein_name": "DNA helicase B", "gene_name": "Helb", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAGQGVLRELLGPLNPYKSDDEEEDCAQEEGEQDSEFVDAEELCSGGIKAGSLPGRMRVSIPDENTKEKCTVYGRFPLKDPWWRVRVRVVKHAQSSKSYQVQGFPSYFLQSDMSPPDQKSICSLFLKECNFTPERIQEFLKWVDKVSSFENLNFENLRETFRNFCRETTKKDKMQSTQSDQGDEQKLEKSFPFVIAMTALQFPKVMEFLPTLFPRHFKSLISSCSETVLGHIEEALGTQPWKLGFRRITYREMKLLSCEASWTSFSQCPSLLQLMTALQKNALVLYSKLRQTCREDGHTYIKVKDLTWGLSEHMSFEEACQSLDFLRTIDVITYEKDFIFLSELYQAEHDIASFICELMNRPPWHLKVDVRNVLASIGGAKSTDSGSTEAVEGSKPDEVEVEVAAEQGDSVLGAQDSGDHVRSNGEHVTSAEINRVPLDRDQVVALETICTNAVTVLSGKGGCGKTTIVSRLFKHVEQLEEREVQQACEDFEQDQGASEEWLDFPKQSPAGVDKAIEVLLTAPTGKAAGLLRQKTHLPAYTLCQVNYSFYMWKKNEADKPWKFSTVRVLVVDEGSLVSVAIFKSVLKLLREHSKLSKLVILGDVRQLPSIEPGNMLQDVFETLKSRQCAIELKTNHRTESQLIVDNAARISRRQFPEFDAEINISDNSTLPNSIQDKTFIFVRLPEEDSSSQSSKGKHQADLYSAVKTLLQGKDFCSPESAKTSQFIAFRRQDCDLINDCCSKHYTDHLIKDHKKKLIFAVGDKICCTRNAYLSDLLPDRDQEANGKGFGDAPDDNAKGKQDFESSIRLCNGEIFFITRDVTDVTSKRKRLLTISNDAGLEVTVDFNKLMTNCQIKHAWARTIHTFQGSEEKTVAYVVGKAGRQHWQHVYTAVTRGRSRVYIIAEESELRSAIRKRSFPRQTRLKHFLQKKLSSSCASSEGLPSQPSSPRVGGRPDTQPLASPLCTTPGSKATANSARGEASPATKERFALDGRWLSTCFSDMDTDEESEQLRGSKRTGDGFPFEEESPSKFRMVEESSPQVSSIFQSLRLNNLTRRQLFKPSDNQETAKSGVVDHTNNASNQETEP", 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"MARQDRLRELLGPLHPYKSDDEEEDCAQEEEGEQEEEFVDAEELCSGGIKAGSLPGRARVSIPDEYTKEKCTVYGRFPLKGPWWRVKVQVLKPQRSRSYQVQGFPAYFLQVDMSPPDQKQICSLFLKECNLASERIQEFLKWVEKVSSFENLHFENLWETLRLFYRETEKKDKKLSTPREQQGEEMRVEKSFAFISAMVALQFPKVMEFLPSLFPRHFKRLISSSSDWVLGCIEDVLGTQPWKLGFRRITYREMKLVRCEASWTAFSQCPSLLQLMTPLQKNALVIYSKLRQTCREDGHTYIEVKDLTSGLSEHMSFEEACQSLAFLKDIDVVIYEKDYVFLSELYEAEQDIASSICELMSRPPWHLKVDVKNVLASIRGAKPNDPGSAEAVEGSKPEEVGSEQGDSVLDAQDGDDHVRSNGEHVANAEINDVPLDQDQVVALETICANAVTVLSGKGGCGKTTIVSRLFKHMEHLEETEVQQACEDFEQDQEASEEWLDCPKQSPAGVDKAVEVLLTAPTGKAAGLLRQRTDLPAYTLCQVNYSFYMWKTKNEVDKPWKFSTVRVLVVDEGSLVSVGIFKSVLQLLCKHSKLSKLIILGDVRQLPSIEPGNMLQDVFETLKSRQCAIELKTNHRTESQLIVDNATRISRRQFPKFDAELNICGNPTLPLSIQDKTFIFVRLPEEDSRSQSSKGEHRSNLYTAVKTLLQGKDFCSFESSKTSQFIAFRRQDCDLINDCCCKHYTGHLIKDHEKKLIFAVGDKICCTRNAYLSDLLPDKDQEAEGKGYGDAPDDDAKIKQDFESSTRLCNGEIFFITRDVTDVTFKRKRLLTINNEAGLEVTVDFSKLMANCQIKHAWARTIHTFQGSEENTVVYVVGKAGRQHWQHVYTAVTRGRSRVYIIAQESELRSATRKRGFPRQTRLKHFLQKKLSGSCAPSTGFASQPSSPRVGGRPDTQPPASHLCRTPDNKATADSARGDERWLSASVNDDVDTDEESAQLRGSKRIGDGFPFDEESPSKFRMVEAPSPQVSSVFQNMRLNTLTPRQLFKPTDNQDTGTAGVADDANDPSNQEMEM", "length": 1074 }, "evidence": [ { "id": "A0A8V0YG75", "url": "https://omabrowser.org/oma/group/A0A8V0YG75/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "negative regulation of double-strand break repair via homologous recombination", "id": "GO:2000042", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000042", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YG75", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG75" } ], "pmid": "" }, { "name": "DNA damage response", "id": "GO:0006974", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006974", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YG75", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG75" } ], "pmid": "" }, { "name": "DNA replication, synthesis of primer", "id": "GO:0006269", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006269", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YG75", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG75" } ], "pmid": "" }, { "name": "regulation of DNA double-strand break processing", "id": "GO:1903775", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903775", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YG75", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG75" } ], "pmid": "" }, { "name": "DNA-templated DNA replication", "id": "GO:0006261", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006261", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YG75", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG75" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 6, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YG75", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG75" } ], "pmid": "" }, { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YG75", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG75" } ], "pmid": "" }, { "name": "DNA helicase activity", "id": "GO:0003678", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003678", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YG75", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG75" } ], "pmid": "" }, { "name": "protein-containing complex binding", "id": "GO:0044877", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044877", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YG75", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG75" } ], "pmid": "" }, { "name": "5'-3' DNA helicase activity", "id": "GO:0043139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043139", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YG75", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG75" } ], "pmid": "" }, { "name": "single-stranded DNA helicase activity", "id": 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"sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YIJ1-1", "uniprot_ac": "A0A8V0YIJ1", "uniprot_id": "A0A8V0YIJ1_CHICK", "mass": { "chemical_mass": 189862.0, "monoisotopic_mass": 189862.0 }, "refseq": { "ac": "XP_015136964", "name": "protein MON2 homolog isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015136964" }, "gene_names": [ { "name": "MON2", "type": "recommended", "evidence": [ { "id": "A0A8V0YIJ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIJ1" } ] }, { "name": "MON2", "type": "synonym", "evidence": [ { "id": "XP_015136964", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015136964" } ] } ], "protein_names": [ { "name": "Protein MON2 homolog", "type": "recommended", "evidence": [ { "id": "A0A8V0YIJ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIJ1/entry#names_and_taxonomy" } ] }, { "name": "protein MON2 homolog isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015136964", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015136964" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015136964", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015136964" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIJ1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MON2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIJ1", "locus": { "chromosome": "1", "start_pos": 33201427, "end_pos": 33110822, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013236", "url": "https://www.ensembl.org/id/ENSGALG00010013236" } ] } } ], "crossref": [ { "id": "ENSGALG00000009795", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000009795", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "417818", "url": "https://www.ncbi.nlm.nih.gov/gene/417818", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015403", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015403", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032629", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032629", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032691", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032691", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032817", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032817", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "AWRLCLN", "url": "https://omabrowser.org/oma/group/AWRLCLN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5P2W5", "url": "https://www.orthodb.org/?gene=A0A1D5P2W5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5P328", "url": "https://www.orthodb.org/?gene=A0A1D5P328", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PSW5", "url": "https://www.orthodb.org/?gene=A0A1D5PSW5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YCT9", "url": "https://www.orthodb.org/?gene=A0A8V0YCT9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YIJ1", "url": "https://www.orthodb.org/?gene=A0A8V0YIJ1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YJ82", "url": "https://www.orthodb.org/?gene=A0A8V0YJ82", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YL88", "url": "https://www.orthodb.org/?gene=A0A8V0YL88", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YR38", "url": "https://www.orthodb.org/?gene=A0A8V0YR38", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10663", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10663", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10663:SF333", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10663:SF333", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF09324", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09324", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12783", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12783", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16206", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16206", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16213", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16213", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015136964", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015136964", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5P2W5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P2W5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5P2W5-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P2W5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5P328", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P328", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5P328-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P328-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PSW5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PSW5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PSW5-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PSW5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YCT9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCT9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YCT9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCT9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YIJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIJ1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YIJ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIJ1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJ82", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ82", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJ82-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ82-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YL88", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL88", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YL88-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL88-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YR38", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YR38", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YR38-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YR38-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSGTSSPEAVKKLLENMQGDLRGLSLECRKKFPPVKEAAESGIIKVKTIAARNTDILAALKENSSEVVQPFLMGCGTKEPKITQLCLAAIQRLMSHEVVSEAAAGNIINMLWQLMENSLEELKLLQTVLVLLTTNTVVHDEALSKAIVLCFRLHFTKDNITNNTAAATVRQVVTVVFERVVAEDERYKDIIEQPVAVQGNSNRRSVSTLKPCAKDAYMLFQDLCQLVNADAPYWLVGMTEMTRTFGLELLESVLNDFPQVFLQHQEFSFLLKERVCPLVIKLFSPNIKFRQGSSTSSSPAPVEKPYFPICMRLLRVVSVLIKQFYSLLVTECEIFLSLLVKFLDADKPQWLRAVAVESIHRLCVQPQLLRSFCQSYDMKQHSTKVFRDIVNALGSFIQSLFLVPSAGNTSVTPNQTGSNASGSTGSAQTNPGVLGMGGGATVLPAFEYRGTWIPILNVTVQGSAKATYLEMLDKVEPPTIPEGYAMSVAFHCLLDLVRGITTMIEGELGEAETVSQSTTETTSLPALSSEHQDSQSISDQSDKELVSRAVWEEMVNACWCGLLAALSLLLDASTDEAATENILKAELTMAALCGRLGLVTSRDAFITAICKGSLPPHYALTVLNSTTAALSSKSYSIQGQNVQMISPSSESHQQVVAVGQPLALQPQGTVMLTSKNIQCMRTLLNLAHCHGAVLGTSWQLVLATLQHLVWILGLKPGVGGALKPGRAVEGPSTVLTTAVMTDLPVISNILSRLFESSQYLDDVSLHHLINALCSLSLEAMDMAYGNNKEPSLFAVAKLLETGLVNMHRIEILWRPLTGHLLEKVCQHPNSRMREWGAEALTSLIKAGLTFSHDPPLSQNQRLQLLLLNPLKELSNISHPDIRIKQLECVLQILQSQGDSLGPGWPLVLGVMGAIRSDQGESLIRTAFQCLQLVVTDFLPTMPCTCLQIVVEVAGSFGLHNQELNISLTSIGLLWNISDYFFQRGEIIEKELNKEEAVLQKQAEEKGVVLNRPFHPAPPFDCLWLCLYAKLGELCVDPRPAVRKSAGQTLFSTIGAHGTLLQHSTWHTVIWKVLFHLLDRVRESSTTADKEKIESGGGNILIHHSRDTAEKQWAETWVLTLAGVARIFNTRRYLLQPLGDFSQAWDVLLDHIQSAALSKNNEVSLAALKSFQEILQIVSPVRDSEKPDTPPAINVSVPVVVGATTATSLGRSFMRTDSIGERMGRYNGAELPVVTDEIEDLNLWWAAWNSWYRIGSESTKPPITCDKLTFIPSQPFLTALIQIFPALYQHIKTGFSMDDLQKLGIILHGAVSVPISSDASPFILPSYTEAVLTSLQEAVLTALDVLQKAICVGSENMQIMYPAIFDQLLAFVEFSCKPPQYGQLETKHIANAKYNQIQLFAPAEWVALNYVPFAERSLEVVVDLYQKTACHKAVVNEKVLQNIIKTLRIPLSLKYSCPSESTWKLAVSSLLKVLSIGLPVARQHASSGKFDSMWPELANTFEDFLFTKSAPPDNLSIQEFQKNESIDVEVVQLISTEILPYANFIPKEFVGQIMTMLNKGSIHSQSSSFTEAEIDIRLREEFSKVCFETLLQFSFSNKVTTPQEGYISRMALSVLLKRSQDVLHRYIEDERLSGKCPLPRQQVTEIIFVLKAVSTLIDSLKKTQPENVDANTWAQVIALYPTLVECITCSSSEVCSALKEALVPFKDFMHPPASKVQNGES", "length": 1720, "header": "tr|A0A8V0YIJ1-1|A0A8V0YIJ1_CHICK Isoform 1 of Protein MON2 homolog OS=Gallus gallus OX=9031 GN=MON2 PE=1 SV=1 CANONICAL=A0A8V0YIJ1-1" }, "isoforms": [ { "isoform_ac": "A0A1D5P2W5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIJ1/entry#A0A1D5P2W5-1", "sequence": { "sequence": "MSGTSSPEAVKKLLENMQGDLRGLSLECRKKFPPVKEAAESGIIKVKTIAARNTDILAALKENSSEVVQPFLMGCGTKEPKITQLCLAAIQRLMSHEVVSEAAAGNIINMLWQLMENSLEELKLLQTVLVLLTTNTVVHDEALSKAIVLCFRLHFTKDNITNNTAAATVRQVVTVVFERVVAEDERYKDIIEQPVAVQGNSNRRSVSTLKPCAKDAYMLFQDLCQLVNADAPYWLVGMTEMTRTFGLELLESVLNDFPQVFLQHQEFSFLLKERVCPLVIKLFSPNIKFRQGSSTSSSPAPVEKPYFPICMRLLRVVSVLIKQFYSLLVTECEIFLSLLVKFLDADKPQWLRAVAVESIHRLCVQPQLLRSFCQSYDMKQHSTKVFRDIVNALGSFIQSLFLVPSAGNTSVTPNQTGSNASGSTGSAQTNPGVLGMGGGATVLPAFEYRGTWIPILNVTVQGSAKATYLEMLDKVEPPTIPEGYAMSVAFHCLLDLVRGITTMIEGELGEAETVSQSTTETTSLPALSSEHQDSQSISDQSDKELVSRAVWEEMVNACWCGLLAALSLLLDASTDEAATENILKAELTMAALCGRLGLVTSRDAFITAICKGSLPPHYALTVLNSTTAALSSKSYSIQGQNVQMISPSSESHQQVVAVGQPLALQPQGTVMLTSKNIQCMRTLLNLAHCHGAVLGTSWQLVLATLQHLVWILGLKPGVGGALKPGRAVEGPSTVLTTAVMTDLPVISNILSRLFESSQYLDDVSLHHLINALCSLSLEAMDMAYGNNKEPSLFAVAKLLETGLVNMHRIEILWRPLTGHLLEVCQHPNSRMREWGAEALTSLIKAGLTFSHDPPLSQNQRLQLLLLNPLKELSNISHPDIRIKQLECVLQILQSQGDSLGPGWPLVLGVMGAIRSDQGESLIRTAFQCLQLVVTDFLPTMPCTCLQIVVEVAGSFGLHNQELNISLTSIGLLWNISDYFFQRGEIIEKELNKEEAVLQKQAEEKGVVLNRPFHPAPPFDCLWLCLYAKLGELCVDPRPAVRKSAGQTLFSTIGAHGTLLQHSTWHTVIWKVLFHLLDRVRESSTTADKEKIESGGGNILIHHSRDTAEKQWAETWVLTLAGVARIFNTRRYLLQPLGDFSQAWDVLLDHIQSAALSKNNEVSLAALKSFQEILQIVSPVRDSEKPDTPPAINVSVPVVVGATTATSLGRSFMRTDSIGERMGRYNGAELPVVTDEIEDLNLWWAAWNSWYRIGSESTKPPITCDKLTFIPSQPFLTALIQIFPALYQHIKTGFSMDDLQKLGIILHGAVSVPISSDASPFILPSYTEAVLTSLQEAVLTALDVLQKAICVGSENMQIMYPAIFDQLLAFVEFSCKPPQYGQLETKHIANAKYNQAEWVALNYVPFAERSLEVVVDLYQKTACHKAVVNEKVLQNIIKTLRIPLSLKYSCPSESTWKLAVSSLLKVLSIGLPVARQHASSGKFDSMWPELANTFEDFLFTKSAPPDNLSIQEFQKNESIDVEVVQLISTEILPYANFIPKEFVGQIMTMLNKGSIHSQSSSFTEAEIDIRLREEFSKVCFETLLQFSFSNKVTTPQEGYISRMALSVLLKRSQDVLHRYIEDERLSGKCPLPRQQVTEIIFVLKAVSTLIDSLKKTQPENVDANTWAQVIALYPTLVECITCSSSEVCSALKEALVPFKDFMHPPASKVFPECIQHI", "length": 1716, "header": "tr|A0A1D5P2W5-1|A0A1D5P2W5_CHICK Computationally mapped isoform of Protein MON2 homolog OS=Gallus gallus OX=9031 GN=MON2 PE=1 SV=1 CANONICAL=A0A8V0YIJ1-1" }, "locus": { "chromosome": "1", "start_pos": 33185408, "end_pos": 33110938, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031834.1", "url": "https://www.ensembl.org/id/ENSGALT00010031834.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018639.1", "url": "https://www.ensembl.org/id/ENSGALP00010018639.1" } ] } }, { "isoform_ac": "A0A1D5P328-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIJ1/entry#A0A1D5P328-1", "sequence": { "sequence": "MSGTSSPEAVKKLLENMQGDLRGLSLECRKKFPPVKEAAESGIIKVKTIAARNTDILAALKENSSEVVQPFLMGCGTKEPKITQLCLAAIQRLMSHEVVSEAAAGNIINMLWQLMENSLEELKLLQTVLVLLTTNTVVHDEALSKAIVLCFRLHFTKDNITNNTAAATVRQVVTVVFERVVAEDERYKDIIEQPVAVQGNSNRRSVSTLKPCAKDAYMLFQDLCQLVNADAPYWLVGMTEMTRTFGLELLESVLNDFPQVFLQHQEFSFLLKERVCPLVIKLFSPNIKFRQGSSTSSSPAPVEKPYFPICMRLLRVVSVLIKQFYSLLVTECEIFLSLLVKFLDADKPQWLRAVAVESIHRLCVQPQLLRSFCQSYDMKQHSTKVFRDIVNALGSFIQSLFLVPSAGNTSVTPNQTGSNASGSTGSAQTNPGVLGMGGGATVLPAFEYRGTWIPILNVTVQGSAKATYLEMLDKVEPPTIPEGYAMSVAFHCLLDLVRGITTMIEGELGEAETVSQSTTETTSLPALSSEHQDSQSISDQSDKELVSRAVWEEMVNACWCGLLAALSLLLDASTDEAATENILKAELTMAALCGRLGLVTSRDAFITAICKGSLPPHYALTVLNSTTAALSSKSYSIQGQNVQMISPSSESHQQVVAVGQPLALQPQGTVMLTSKNIQCMRTLLNLAHCHGAVLGTSWQLVLATLQHLVWILGLKPGVGGALKPGRAVEGPSTVLTTAVMTDLPVISNILSRLFESSQYLDDVSLHHLINALCSLSLEAMDMAYGNNKEPSLFAVAKLLETGLVNMHRIEILWRPLTGHLLEVCQHPNSRMREWGAEALTSLIKAGLTFSHDPPLSQNQRLQLLLLNPLKELSNISHPDIRIKQLECVLQILQSQGDSLGPGWPLVLGVMGAIRSDQGESLIRTAFQCLQLVVTDFLPTMPCTCLQIVVEVAGSFGLHNQELNISLTSIGLLWNISDYFFQRGEIIEKELNKEEAVLQKQAEEKGVVLNRPFHPAPPFDCLWLCLYAKLGELCVDPRPAVRKSAGQTLFSTIGAHGTLLQHSTWHTVIWKVLFHLLDRVRESSTTADKEKIESGGGNILIHHSRDTAEKQWAETWVLTLAGVARIFNTRRYLLQPLGDFSQAWDVLLDHIQSAALSKNNEVSLAALKSFQEILQIVSPVRDSEKPDTPPAINVSVPVVVGATTATSLGRSFMRTDSIGERMGRYNGAELPVVTDEIEDLNLWWAAWNSWYRIGSESTKPPITCDKLTFIPSQPFLTALIQIFPALYQHIKTGFSMDDLQKLGIILHGAVSVPISSDASPFILPSYTEAVLTSLQEAVLTALDVLQKAICVGSENMQIMYPAIFDQLLAFVEFSCKPPQYGQLETKHIANAKYNQAEWVALNYVPFAERSLEVVVDLYQKTACHKAVVNEKVLQNIIKTLRIPLSLKYSCPSESTWKLAVSSLLKVLSIGLPVARQHASSGKFDSMWPELANTFEDFLFTKSAPPDNLSIQEFQKNESIDVEVVQLISTEILPYANFIPKEFVGQIMTMLNKGSIHSQSSSFTEAEIDIRLREEFSKVCFETLLQFSFSNKVTTPQEGYISRMALSVLLKRSQDVLHRYIEDERLSGKCPLPRQQVTEIIFVLKAVSTLIDSLKKTQPENVDANTWAQVIALYPTLVECITCSSSEVCSALKEALVPFKDFMHPPASKAQIS", "length": 1711, "header": "tr|A0A1D5P328-1|A0A1D5P328_CHICK Computationally mapped isoform of Protein MON2 homolog OS=Gallus gallus OX=9031 GN=MON2 PE=1 SV=2 CANONICAL=A0A8V0YIJ1-1" }, "locus": { "chromosome": "1", "start_pos": 33201218, "end_pos": 33110938, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031825.1", "url": "https://www.ensembl.org/id/ENSGALT00010031825.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018633.1", "url": "https://www.ensembl.org/id/ENSGALP00010018633.1" } ] } }, { "isoform_ac": "A0A1D5PSW5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIJ1/entry#A0A1D5PSW5-1", "sequence": { "sequence": "MSGTSSPEAVKKLLENMQGDLRGLSLECRKKFPPVKEAAESGIIKVKTIAARNTDILAALKENSSEVVQPFLMGCGTKEPKITQLCLAAIQRLMSHEVVSEAAAGNIINMLWQLMENSLEELKLLQTVLVLLTTNTVVHDEALSKAIVLCFRLHFTKDNITNNTAAATVRQVVTVVFERVVAEDERYKDIIEQPVAVQGNSNRRSVSTLKPCAKDAYMLFQDLCQLVNADAPYWLVGMTEMTRTFGLELLESVLNDFPQVFLQHQEFSFLLKERVCPLVIKLFSPNIKFRQGSSTSSSPAPVEKPYFPICMRLLRVVSVLIKQFYSLLVTECEIFLSLLVKFLDADKPQWLRAVAVESIHRLCVQPQLLRSFCQSYDMKQHSTKVFRDIVNALGSFIQSLFLVPSAGNTSVTPNQTGSNASGSTGSAQTNPGVLGMGGGATVLPAFEYRGTWIPILNVTVQGSAKATYLEMLDKVEPPTIPEGYAMSVAFHCLLDLVRGITTMIEGELGEAETVSQSTTETTSLPALSSEHQDSQSISDQSDKELVSRAVWEEMVNACWCGLLAALSLLLDASTDEAATENILKAELTMAALCGRLGLVTSRDAFITAICKGSLPPHYALTVLNSTTAALSSKSYSIQGQNVQMISPSSESHQQVVAVGQPLALQPQGTVMLTSKNIQCMRTLLNLAHCHGAVLGTSWQLVLATLQHLVWILGLKPGVGGALKPGRAVEGPSTVLTTAVMTDLPVISNILSRLFESSQYLDDVSLHHLINALCSLSLEAMDMAYGNNKEPSLFAVAKLLETGLVNMHRIEILWRPLTGHLLEVCQHPNSRMREWGAEALTSLIKAGLTFSHDPPLSQNQRLQLLLLNPLKELSNISHPDIRIKQLECVLQILQSQGDSLGPGWPLVLGVMGAIRSDQGESLIRTAFQCLQLVVTDFLPTMPCTCLQIVVEVAGSFGLHNQELNISLTSIGLLWNISDYFFQRGEIIEKELNKEEAVLQKQAEEKGVVLNRPFHPAPPFDCLWLCLYAKLGELCVDPRPAVRKSAGQTLFSTIGAHGTLLQHSTWHTVIWKVLFHLLDRVRESSTTADKEKIESGGGNILIHHSRDTAEKQWAETWVLTLAGVARIFNTRRYLLQPLGDFSQAWDVLLDHIQSAALSKNNEVSLAALKSFQEILQIVSPVRDSEKPDTPPAINVSVPVVVGATTATSLGRSFMRTDSIGERMGRYNGAELPVVTDEIEDLNLWWAAWNSWYRIGSESTKPPITCDKLTFIPSQPFLTALIQIFPALYQHIKTGFSMDDLQKLGIILHGAVSVPISSDASPFILPSYTEAVLTSLQEAVLTALDVLQKAICVGSENMQIMYPAIFDQLLAFVEFSCKPPQYGQLETKHIANAKYNQAEWVALNYVPFAERSLEVVVDLYQKTACHKAVVNEKVLQNIIKTLRIPLSLKYSCPSESTWKLAVSSLLKVLSIGLPVARQHASSGKFDSMWPELANTFEDFLFTKSAPPDNLSIQEFQKNESIDVEVVQLISTEILPYANFIPKEFVGQIMTMLNKGSIHSQSSSFTEAEIDIRLREEFSKVCFETLLQFSFSNKVTTPQEGYISRMALSVLLKRSQDVLHRYIEDERLSGKCPLPRQQVTEIIFVLKAVSTLIDSLKKTQPENVDANTWAQVIALYPTLVECITCSSSEVCSALKEALVPFKDFMHPPASKVTFL", "length": 1711, "header": "tr|A0A1D5PSW5-1|A0A1D5PSW5_CHICK Computationally mapped isoform of Protein MON2 homolog OS=Gallus gallus OX=9031 GN=MON2 PE=1 SV=2 CANONICAL=A0A8V0YIJ1-1" }, "locus": { "chromosome": "1", "start_pos": 33180291, "end_pos": 33110938, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031809.1", "url": "https://www.ensembl.org/id/ENSGALT00010031809.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018624.1", "url": "https://www.ensembl.org/id/ENSGALP00010018624.1" } ] } }, { "isoform_ac": "A0A8V0YCT9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIJ1/entry#A0A8V0YCT9-1", "sequence": { "sequence": "MSGTSSPEAVKKLLENMQGDLRGLSLECRKKFPPVKEAAESGIIKVKTIAARNTDILAVEKLCQVMSAMHQNTQMNKRNLPLAIWEASNILCNITV", "length": 96, "header": "tr|A0A8V0YCT9-1|A0A8V0YIJ1_CHICK Computationally mapped isoform of Protein MON2 homolog OS=Gallus gallus OX=9031 GN=MON2 PE=1 SV=1 CANONICAL=A0A8V0YIJ1-1" }, "locus": { "chromosome": "1", "start_pos": 33126786, "end_pos": 33110938, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031794.1", "url": "https://www.ensembl.org/id/ENSGALT00010031794.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018612.1", "url": "https://www.ensembl.org/id/ENSGALP00010018612.1" } ] } }, { "isoform_ac": "A0A8V0YIJ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIJ1/entry#A0A8V0YIJ1-1", "sequence": { "sequence": "MSGTSSPEAVKKLLENMQGDLRGLSLECRKKFPPVKEAAESGIIKVKTIAARNTDILAALKENSSEVVQPFLMGCGTKEPKITQLCLAAIQRLMSHEVVSEAAAGNIINMLWQLMENSLEELKLLQTVLVLLTTNTVVHDEALSKAIVLCFRLHFTKDNITNNTAAATVRQVVTVVFERVVAEDERYKDIIEQPVAVQGNSNRRSVSTLKPCAKDAYMLFQDLCQLVNADAPYWLVGMTEMTRTFGLELLESVLNDFPQVFLQHQEFSFLLKERVCPLVIKLFSPNIKFRQGSSTSSSPAPVEKPYFPICMRLLRVVSVLIKQFYSLLVTECEIFLSLLVKFLDADKPQWLRAVAVESIHRLCVQPQLLRSFCQSYDMKQHSTKVFRDIVNALGSFIQSLFLVPSAGNTSVTPNQTGSNASGSTGSAQTNPGVLGMGGGATVLPAFEYRGTWIPILNVTVQGSAKATYLEMLDKVEPPTIPEGYAMSVAFHCLLDLVRGITTMIEGELGEAETVSQSTTETTSLPALSSEHQDSQSISDQSDKELVSRAVWEEMVNACWCGLLAALSLLLDASTDEAATENILKAELTMAALCGRLGLVTSRDAFITAICKGSLPPHYALTVLNSTTAALSSKSYSIQGQNVQMISPSSESHQQVVAVGQPLALQPQGTVMLTSKNIQCMRTLLNLAHCHGAVLGTSWQLVLATLQHLVWILGLKPGVGGALKPGRAVEGPSTVLTTAVMTDLPVISNILSRLFESSQYLDDVSLHHLINALCSLSLEAMDMAYGNNKEPSLFAVAKLLETGLVNMHRIEILWRPLTGHLLEKVCQHPNSRMREWGAEALTSLIKAGLTFSHDPPLSQNQRLQLLLLNPLKELSNISHPDIRIKQLECVLQILQSQGDSLGPGWPLVLGVMGAIRSDQGESLIRTAFQCLQLVVTDFLPTMPCTCLQIVVEVAGSFGLHNQELNISLTSIGLLWNISDYFFQRGEIIEKELNKEEAVLQKQAEEKGVVLNRPFHPAPPFDCLWLCLYAKLGELCVDPRPAVRKSAGQTLFSTIGAHGTLLQHSTWHTVIWKVLFHLLDRVRESSTTADKEKIESGGGNILIHHSRDTAEKQWAETWVLTLAGVARIFNTRRYLLQPLGDFSQAWDVLLDHIQSAALSKNNEVSLAALKSFQEILQIVSPVRDSEKPDTPPAINVSVPVVVGATTATSLGRSFMRTDSIGERMGRYNGAELPVVTDEIEDLNLWWAAWNSWYRIGSESTKPPITCDKLTFIPSQPFLTALIQIFPALYQHIKTGFSMDDLQKLGIILHGAVSVPISSDASPFILPSYTEAVLTSLQEAVLTALDVLQKAICVGSENMQIMYPAIFDQLLAFVEFSCKPPQYGQLETKHIANAKYNQIQLFAPAEWVALNYVPFAERSLEVVVDLYQKTACHKAVVNEKVLQNIIKTLRIPLSLKYSCPSESTWKLAVSSLLKVLSIGLPVARQHASSGKFDSMWPELANTFEDFLFTKSAPPDNLSIQEFQKNESIDVEVVQLISTEILPYANFIPKEFVGQIMTMLNKGSIHSQSSSFTEAEIDIRLREEFSKVCFETLLQFSFSNKVTTPQEGYISRMALSVLLKRSQDVLHRYIEDERLSGKCPLPRQQVTEIIFVLKAVSTLIDSLKKTQPENVDANTWAQVIALYPTLVECITCSSSEVCSALKEALVPFKDFMHPPASKVQNGES", "length": 1720, "header": "tr|A0A8V0YIJ1-1|A0A8V0YIJ1_CHICK Isoform 1 of Protein MON2 homolog OS=Gallus gallus OX=9031 GN=MON2 PE=1 SV=1 CANONICAL=A0A8V0YIJ1-1" }, "locus": { "chromosome": "1", "start_pos": 33180210, "end_pos": 33110938, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031836.1", "url": "https://www.ensembl.org/id/ENSGALT00010031836.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018641.1", "url": "https://www.ensembl.org/id/ENSGALP00010018641.1" } ] } }, { "isoform_ac": "A0A8V0YJ82-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIJ1/entry#A0A8V0YJ82-1", "sequence": { "sequence": "MNADISGKTMPALKENSSEVVQPFLMGCGTKEPKITQLCLAAIQRLMSHEVVSEAAAGNIINMLWQLMENSLEELKLLQTVLVLLTTNTVVHDEALSKAIVLCFRLHFTKDNITNNTAAATVRQVVTVVFERVVAEDERYKDIIEQPVAVQGNSNRRSVSTLKPCAKDAYMLFQDLCQLVNADAPYWLVGMTEMTRTFGLELLESVLNDFPQVFLQHQEFSFLLKERVCPLVIKLFSPNIKFRQGSSTSSSPAPVEKPYFPICMRLLRVVSVLIKQFYSLLVTECEIFLSLLVKFLDADKPQWLRAVAVESIHRLCVQPQLLRSFCQSYDMKQHSTKVFRDIVNALGSFIQSLFLVPSAGNTSVTPNQTGSNASGSTGSAQTNPGVLGMGGGATVLPAFEYRGTWIPILNVTVQGSAKATYLEMLDKVEPPTIPEGYAMSVAFHCLLDLVRGITTMIEGELGEAETVSQSTTETTSLPALSSEHQDSQSISDQSDKELVSRAVWEEMVNACWCGLLAALSLLLDASTDEAATENILKAELTMAALCGRLGLVTSRDAFITAICKGSLPPHYALTVLNSTTAALSSKSYSIQGQNVQMISPSSESHQQVVAVGQPLALQPQGTVMLTSKNIQCMRTLLNLAHCHGAVLGTSWQLVLATLQHLVWILGLKPGVGGALKPGRAVEGPSTVLTTAVMTDLPVISNILSRLFESSQYLDDVSLHHLINALCSLSLEAMDMAYGNNKEPSLFAVAKLLETGLVNMHRIEILWRPLTGHLLEVCQHPNSRMREWGAEALTSLIKAGLTFSHDPPLSQNQRLQLLLLNPLKELSNISHPDIRIKQLECVLQILQSQGDSLGPGWPLVLGVMGAIRSDQGESLIRTAFQCLQLVVTDFLPTMPCTCLQIVVEVAGSFGLHNQELNISLTSIGLLWNISDYFFQRGEIIEKELNKEEAVLQKQAEEKGVVLNRPFHPAPPFDCLWLCLYAKLGELCVDPRPAVRKSAGQTLFSTIGAHGTLLQHSTWHTVIWKVLFHLLDRVRESSTTADKEKIESGGGNILIHHSRDTAEKQWAETWVLTLAGVARIFNTRRYLLQPLGDFSQAWDVLLDHIQSAALSKNNEVSLAALKSFQEILQIVSPVRDSEKPDTPPAINVSVPVVVGATTATSLGRSFMRTDSIGERMGRYNGAELPVVTDEIEDLNLWWAAWNSWYRIGSESTKPPITCDKLTFIPSQPFLTALIQIFPALYQHIKTGFSMDDLQKLGIILHGAVSVPISSDASPFILPSYTEAVLTSLQEAVLTALDVLQKAICVGSENMQIMYPAIFDQLLAFVEFSCKPPQYGQLETKHIANAKYNQAEWVALNYVPFAERSLEVVVDLYQKTACHKAVVNEKVLQNIIKTLRIPLSLKYSCPSESTWKLAVSSLLKVLSIGLPVARQHASSGKFDSMWPELANTFEDFLFTKSAPPDNLSIQEFQKNESIDVEVVQLISTEILPYANFIPKEFVGQIMTMLNKGSIHSQSSSFTEAEIDIRLREEFSKVCFETLLQFSFSNKVTTPQEGYISRMALSVLLKRSQDVLHRYIEDERLSGKCPLPRQQVTEIIFVLKAVSTLIDSLKKTQPENVDANTWAQVIALYPTLVECITCSSSEVCSALKEALVPFKDFMHPPASKVQNGES", "length": 1666, "header": "tr|A0A8V0YJ82-1|A0A8V0YJ82_CHICK Computationally mapped isoform of Protein MON2 homolog OS=Gallus gallus OX=9031 GN=MON2 PE=1 SV=1 CANONICAL=A0A8V0YIJ1-1" }, "locus": { "chromosome": "1", "start_pos": 33180210, "end_pos": 33126657, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031802.1", "url": "https://www.ensembl.org/id/ENSGALT00010031802.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018619.1", "url": "https://www.ensembl.org/id/ENSGALP00010018619.1" } ] } }, { "isoform_ac": "A0A8V0YL88-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIJ1/entry#A0A8V0YL88-1", "sequence": { "sequence": "MSGTSSPEAVKKLLENMQGDLRGLSLECRKKFPPVKERKGKSTDVLTQIKLQNQRSTWEIRRRLSVWKKAAESGIIKVKTIAARNTDILAALKENSSEVVQPFLMGCGTKEPKITQLCLAAIQRLMSHEVVSEAAAGNIINMLWQLMENSLEELKLLQTVLVLLTTNTVVHDEALSKAIVLCFRLHFTKDNITNNTAAATVRQVVTVVFERVVAEDERYKDIIEQPVAVQGNSNRRSVSTLKPCAKDAYMLFQDLCQLVNADAPYWLVGMTEMTRTFGLELLESVLNDFPQVFLQHQEFSFLLKERVCPLVIKLFSPNIKFRQGSSTSSSPAPVEKPYFPICMRLLRVVSVLIKQFYSLLVTECEIFLSLLVKFLDADKPQWLRAVAVESIHRLCVQPQLLRSFCQSYDMKQHSTKVFRDIVNALGSFIQSLFLVPSAGNTSVTPNQTGSNASGSTGSAQTNPGVLGMGGGATVLPAFEYRGTWIPILNVTVQGSAKATYLEMLDKVEPPTIPEGYAMSVAFHCLLDLVRGITTMIEGELGEAETVSQSTTETTSLPALSSEHQDSQSISDQSDKELVSRAVWEEMVNACWCGLLAALSLLLDASTDEAATENILKAELTMAALCGRLGLVTSRDAFITAICKGSLPPHYALTVLNSTTAALSSKSYSIQGQNVQMISPSSESHQQVVAVGQPLALQPQGTVMLTSKNIQCMRTLLNLAHCHGAVLGTSWQLVLATLQHLVWILGLKPGVGGALKPGRAVEGPSTVLTTAVMTDLPVISNILSRLFESSQYLDDVSLHHLINALCSLSLEAMDMAYGNNKEPSLFAVAKLLETGLVNMHRIEILWRPLTGHLLEVCQHPNSRMREWGAEALTSLIKAGLTFSHDPPLSQNQRLQLLLLNPLKELSNISHPDIRIKQLECVLQILQSQGDSLGPGWPLVLGVMGAIRSDQGESLIRTAFQCLQLVVTDFLPTMPCTCLQIVVEVAGSFGLHNQELNISLTSIGLLWNISDYFFQRGEIIEKELNKEEAVLQKQAEEKGVVLNRPFHPAPPFDCLWLCLYAKLGELCVDPRPAVRKSAGQTLFSTIGAHGTLLQHSTWHTVIWKVLFHLLDRVRESSTTADKEKIESGGGNILIHHSRDTAEKQWAETWVLTLAGVARIFNTRRYLLQPLGDFSQAWDVLLDHIQSAALSKNNEVSLAALKSFQEILQIVSPVRDSEKPDTPPAINVSVPVVVGATTATSLGRSFMRTDSIGERMGRYNGAELPVVTDEIEDLNLWWAAWNSWYRIGSESTKPPITCDKLTFIPSQPFLTALIQIFPALYQHIKTGFSMDDLQKLGIILHGAVSVPISSDASPFILPSYTEAVLTSLQEAVLTALDVLQKAICVGSENMQIMYPAIFDQLLAFVEFSCKPPQYGQLETKHIANAKYNQAEWVALNYVPFAERSLEVVVDLYQKTACHKAVVNEKVLQNIIKTLRIPLSLKYSCPSESTWKLAVSSLLKVLSIGLPVARQHASSGKFDSMWPELANTFEDFLFTKSAPPDNLSIQEFQKNESIDVEVVQLISTEILPYANFIPKEFVGQIMTMLNKGSIHSQSSSFTEAEIDIRLREEFSKVCFETLLQFSFSNKVTTPQEGYISRMALSVLLKRSQDVLHRYIEDERLSGKCPLPRQQVTEIIFVLKAVSTLIDSLKKTQPENVDANTWAQVIALYPTLVECITCSSSEVCSALKEALVPFKDFMHPPASKVQNGES", "length": 1745, "header": "tr|A0A8V0YL88-1|A0A8V0YL88_CHICK Computationally mapped isoform of Protein MON2 homolog OS=Gallus gallus OX=9031 GN=MON2 PE=1 SV=1 CANONICAL=A0A8V0YIJ1-1" }, "locus": { "chromosome": "1", "start_pos": 33180210, "end_pos": 33110938, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031840.1", "url": "https://www.ensembl.org/id/ENSGALT00010031840.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018645.1", "url": "https://www.ensembl.org/id/ENSGALP00010018645.1" } ] } }, { "isoform_ac": "A0A8V0YR38-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIJ1/entry#A0A8V0YR38-1", "sequence": { "sequence": "MGLLRSSSARAAESGIIKVKTIAARNTDILAALKENSSEVVQPFLMGCGTKEPKITQLCLAAIQRLMSHEVVSEAAAGNIINMLWQLMENSLEELKLLQTVLVLLTTNTVVHDEALSKAIVLCFRLHFTKDNITNNTAAATVRQVVTVVFERVVAEDERYKDIIEQPVAVQGNSNRRSVSTLKPCAKDAYMLFQDLCQLVNADAPYWLVGMTEMTRTFGLELLESVLNDFPQVFLQHQEFSFLLKERVCPLVIKLFSPNIKFRQGSSTSSSPAPVEKPYFPICMRLLRVVSVLIKQFYSLLVTECEIFLSLLVKFLDADKPQWLRAVAVESIHRLCVQPQLLRSFCQSYDMKQHSTKVFRDIVNALGSFIQSLFLVPSAGNTSVTPNQTGSNASGSTGSAQTNPGVLGMGGGATVLPAFEYRGTWIPILNVTVQGSAKATYLEMLDKVEPPTIPEGYAMSVAFHCLLDLVRGITTMIEGELGEAETVSQSTTETTSLPALSSEHQDSQSISDQSDKELVSRAVWEEMVNACWCGLLAALSLLLDASTDEAATENILKAELTMAALCGRLGLVTSRDAFITAICKGSLPPHYALTVLNSTTAALSSKSYSIQGQNVQMISPSSESHQQVVAVGQPLALQPQGTVMLTSKNIQCMRTLLNLAHCHGAVLGTSWQLVLATLQHLVWILGLKPGVGGALKPGRAVEGPSTVLTTAVMTDLPVISNILSRLFESSQYLDDVSLHHLINALCSLSLEAMDMAYGNNKEPSLFAVAKLLETGLVNMHRIEILWRPLTGHLLEVCQHPNSRMREWGAEALTSLIKAGLTFSHDPPLSQNQRLQLLLLNPLKELSNISHPDIRIKQLECVLQILQSQGDSLGPGWPLVLGVMGAIRSDQGESLIRTAFQCLQLVVTDFLPTMPCTCLQIVVEVAGSFGLHNQELNISLTSIGLLWNISDYFFQRGEIIEKELNKEEAVLQKQAEEKGVVLNRPFHPAPPFDCLWLCLYAKLGELCVDPRPAVRKSAGQTLFSTIGAHGTLLQHSTWHTVIWKVLFHLLDRVRESSTTADKEKIESGGGNILIHHSRDTAEKQWAETWVLTLAGVARIFNTRRYLLQPLGDFSQAWDVLLDHIQSAALSKNNEVSLAALKSFQEILQIVSPVRDSEKPDTPPAINVSVPVVVGATTATSLGRSFMRTDSIGERMGRYNGAELPVVTDEIEDLNLWWAAWNSWYRIGSESTKPPITCDKLTFIPSQPFLTALIQIFPALYQHIKTGFSMDDLQKLGIILHGAVSVPISSDASPFILPSYTEAVLTSLQEAVLTALDVLQKAICVGSENMQIMYPAIFDQLLAFVEFSCKPPQYGQLETKHIANAKYNQAEWVALNYVPFAERSLEVVVDLYQKTACHKAVVNEKVLQNIIKTLRIPLSLKYSCPSESTWKLAVSSLLKVLSIGLPVARQHASSGKFDSMWPELANTFEDFLFTKSAPPDNLSIQEFQKNESIDVEVVQLISTEILPYANFIPKEFVGQIMTMLNKGSIHSQSSSFTEAEIDIRLREEFSKVCFETLLQFSFSNKVTTPQEGYISRMALSVLLKRSQDVLHRYIEDERLSGKCPLPRQQVTEIIFVLKAVSTLIDSLKKTQPENVDANTWAQVIALYPTLVECITCSSSEVCSALKEALVPFKDFMHPPASKVQNGES", "length": 1686, "header": "tr|A0A8V0YR38-1|A0A8V0YR38_CHICK Computationally mapped isoform of Protein MON2 homolog OS=Gallus gallus OX=9031 GN=MON2 PE=1 SV=1 CANONICAL=A0A8V0YIJ1-1" }, "locus": { "chromosome": "1", "start_pos": 33180210, "end_pos": 33113146, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031818.1", "url": "https://www.ensembl.org/id/ENSGALT00010031818.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018628.1", "url": "https://www.ensembl.org/id/ENSGALP00010018628.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0AAA9T6Y7-1", "protein_name": "Protein MON2 homolog", "gene_name": "MON2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSGTNSPEAVKKLLENMQSDLRALSLECKKKFPPVKEAAESGIIKVKTIAARNTEILAALKENSSEVVQPFLMGCGTKEPKITQLCLAAIQRLMSHEVVSETAAGNIINMLWQLMENSLEELKLLQTVLVLLTTNTVVHDEALSKAIVLCFRLHFTKDNITNNTAAATVRQVVTVVFERMVAEDERHRDITDQPVLVQGNSNRRSVSTLKPCAKDAYMLFQDLCQLVNADAPYWLVGMTEMTRTFGLELLESVLNDFPQVFLQHQEFSFLLKERVCPLVIKLFSPNIKFRQGSSTSSSPAPVEKPYFPICMRLLRVVSVLIKQFYSLLVTECEIFLSLLVKFLDADKPQWLRAVAVESIHRLCVQPQLLRSFCQSYDMKQHSTKVFRDIVNALGSFIQSLFLVPPTGNPAATNQAGNNNSGGPVSAPANSGMLGIGGGVTLLPAFEYRGTWIPILTVTVQGSAKATYLEMLDKVEPPTIPEGYAMSVAFHCLLDLVRGITNMIEGELGEVETECQTTTTEAVSSPTQSSEQQELQSTSDQMDKEIVSRAVWEEMVNACWCGLLAALSLLLDASTDEAATENILKAELTMAALCGRLGLVTSRDAFITAICKGSLPPHYALTVLNTTTAATLSNKSYSIQGQSVMMISPSSESHQQVVAVGQPLAVQPQGTVMLTSKNIQCMRTLLNLAHCHGAVLGTSWQLVLATLQHLVWILGLKPSSGGALKPGRAVEGPSTVLTTAVMTDLPVISNILSRLFESSQYLDDVSLHHLINALCSLSLEAMDMAYGNNKEPSLFAVAKLLETGLVNMHRIEILWRPLTGHLLEKVCQHPNSRMREWGAEALTSLIKAGLTFNHDPPLSQNQRLQLLLLNPLKEMSNINHPDIRLKQLECVLQILQSQGDSLGPGWPLVLGVMGAIRNDQGESLIRTAFQCLQLVVTDFLPTMPCTCLQIVVDVAGSFGLHNQELNISLTSIGLLWNISDYFFQRGETIEKELNKEEAAQQKQAEEKGVVLNRPFHPAPPFDCLWLCLYAKLGELCVDPRPAVRKSAGQTLFSTIGAHGTLLQHSTWHTVIWKVLFHLLDRVRESSTTADKEKIESGGGNILIHHSRDTAEKQWAETWVLTLAGVARIFNTRRYLLQPLGDFSRAWDVLLDHIQSAALSKNNEVSLAALKSFQEILQIVSPVRDSDKPETPPAVNVPAPVLLGPISGPSLNRPFVRTDSIGERLGRYSSSEPPVVTDELEDLNLWWAAWNTWYRIGSESTKPPITLDKLTFIPSQPFLTALIQIFPALYQHIKTGFNMDDLQKLGVILHRAVSVPISSDASPFILPSYTEAVLTSLQEAVLTALDVLQKAICVGPENMQIMYPAIFDQLLAFVEFSCKPPQYGQLETKHIANAKYNQIQLFAPAEWVALNYVPFAERSLDVVVDLYQKTACHKAVVNEKVLQNIIKTLRVPLSLKYSCPSESTWKLAVSSLLKVLSIGLPVARQHASSGKFDSMWPELANTFEDFLFTKSIPPDNLSIQEFQRNESIDVEVVQLISTEILPYANFIPKEFVGQIMTMLNKGSIHSQSSSFTEAEIDIRLREEFSKMCFETLLQFSFSNKVTTPQEGYISRMALSVLLKRSQDVLHRYIEDERLSGKCPLPRQQVTEIIFVLKAVSTLIDSLKKTKPENVDGNTWAQVIALYPTLVECITCSSSEVCSALKEALVPFKDFMQPPTSKVQNGES", "length": 1721 }, "evidence": [ { "id": "A0A8V0YIJ1", "url": "https://omabrowser.org/oma/group/A0A8V0YIJ1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F4K5S0-1", "protein_name": "ARM repeat superfamily protein", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MALVAALEADLRALSAEARRRYPAVKDGAEHAILKLRSSSSASDLSSNEDILRIFLMACGVRNTKLSVIGLSCLQKLISHDAVEPSSLKEILYTLKDHSEMAEENIQLKTLQTILIIFQSRLHPETEDNMVLGLSICLTLLDNNRPPSVYNTAAATFRQAVALIFDQVVSAESLPMPKFGSSSQTARTGSVTGDLSQNINNSGPLEKDVIGGRLTIRDTLSETGKLGLRLLEDLTASAAGGSAAWLHVTSLPRTFSLELIEFVLSNYISVFKILLPYEQVLRHQICSLLMTSLRTSSELEGEMVEPYFRRLVLRSVAHIIRLYSSSLITECEVFLSMLVKATFLDLPLWHRILVLEILRGFCVEARTLRILFQNFDMKLPSRSFFTLQLKKHPKNTNVVESMVKALARVVSSIQFQETSEESLAAVAGMFSSKAKGIEWILDNDASSAAVLVASEAHAITLAIEGLLGVVFTVATLTDEAVDVGELESPRYEHLPSSDYTGKTSLLCISMVDSLWLTILDAFSLILSRSQGEAIVLEILKGYQAFTQACGVLHAVEPLNSFLASLCKFTIVLPTDVERKSSVVQSPVSKRSEVQVDLKDVIVLTPKNVQALRTLFNIAHRLHNVLGPSWVLVLETLAALDRAIHSPHATTQEVATAVPKLTREPSRQYADFSILSSLNSQLFESSALMQVSSVKSLLSALHMLSHQSMTETSGSVSSASSKQIGSISFSVDRMISILVNNLHRVEPLWDQVVGHFLELAEHSNQNLRNMALDALDQSICAVLGSEQFGEDPARSRDATLDVDSKSTEVKSVECAVLSSLRVLYFSAQKADVRVGSLKILLHVLERCGEKLYYSWSSILEMLRSVADASEKDVATLGFQSLRVIMSDGLPTLPEDCLHVCIDVTGAYSAQKTDLNISLTAIGLLWTLTDFVAKGLHHGSLVEKGSGFNNADSTPQQTNGEDGEKHMGSNSGKSDYEAPIQVVNHEKLLFLVFSLIQKLVDDERPEVRNSAVRTFFQILGSHGNKLSKSMWEDCLWNYIFPMLDGASHKAATSSKDEWQGKEIGTRGGKAVHMLIHHSRNSAQKQWDETFVLVLGGIARLFRSYFPLLESLPNFWSGWESLLAFVKKSIFNGSKEVSLAAINCLQTAVVSHCVKGNLQLRYLNSVLDVYELVFQKSSSYTGDTAAKVKQEILHGLGELYVQSSKMFDDKMYMQLLGIVDLAIKQAIINSENFETEYGHVPPVLRHVLEILPSLGPPEHLSSMWLILLREFLHYLPRVDSVLPNDEGSEVLEQKADASSETIPTTRITTNMFAEKLIPALIELLLQAPAVEKYILFPEVIQNLRRCMMTRRDNPDGSLWKVAAEGFNRLLVEDVKLCSVGGETELKISKTARIRIWKEIGDVYDIFLVGYCGRALSSNSLPAATLKANETLEIALLNGLGDIILKSTVDAPREVLERLVSTLDRCASRTCSLPVETVELMPAHCSRFSLTCLQKLFSLSSFSSETENWHSTRAEVSKISITTLMARCEFILSRFLIDENNLGNRPIPTARLEEIIFTLQELYRLSIHPEVASVLPLQPYLKNVLREDNRDTRAHLLVLFPSLCEIVLSREMRVRELVQILLRAVATELGLEKRVLNYSVCCILQYAILRDFMLVWFNKVLC", "length": 1658 }, "evidence": [ { "id": "A0A8V0YIJ1", "url": "https://omabrowser.org/oma/group/A0A8V0YIJ1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "P48563-1", "protein_name": "Protein MON2", "gene_name": "MON2", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MAMNTGGFDSMQRQLEAELRSLSSESKRRNSTIRHASDKSIEILKRVHSFEELERHPDFALPFVLACQSRNAKMTTLAMQCLQGLSTVPSIPRSRLSEILDAFIEATHLAMEIQLKVLQVVPIFFKTYGKFIYGPLCKKLLLCCSNLLHVPNKAPVVVGTASATLQQLIDEIFDRLSIESVVDDKQYEVLISNSESIKVNVYRYDANKLFDNICSLNEISSNGAVSDEEMLLDIGDIPIDYGLEILESILKNSQKNLLECQDLQYLLRVKAIPLLLRCISSSRHFSTAVRSCRCLKLLIRKEYLSILELELEVILSLLIHGISVESNLSGWQRVLSLELFKDLSQDPEIVNTLYMDYDNYPDKKHVFKYLLKECIVLLNSPEYITFLAPSKVVEKMDSPLITTENSTVKTKFMHLLDKSNAPSINITYIISLILTICNHLCEGLNKSALESSPLEKKIEDKEREEGTGNDSTVVKVYSGLFSGLFELNKLFLYSTSLETSIFHLVVRAFQKLAHSAGVLSLKDKLRACMKLFSILITNNVTSSNQYSFNDTSKSAKNQHTRNISTSSVTTSPVESTKNPSRSIADSAQNKEMKRRLHPRNISSRQVSLLRALISLSISLGPIFDSESWRYTFLTWQWITYYIYGPSADFKESFYSEDIPPPPILTKSDVTSIESSLTKFFESTSSYSCSTFHLVLTRLILDSKNTLTLEQTNLNLNNDIGYHPLDAKDEIIPCIYNKAFFVNKIGELATYNCKKFLFGKNGKELWSLISTYMIKLISNREMDNDSLRLYTVRVFTDIIKKATNEVGNSDEQDNKVKQFGTLENLVIDSLMATINSIKQLDIGKQEIYNGTINVESDILFQLLLTLKEILNEFGELLMNSWTNIFNIINSPFEWTVEDTDFSVNEDIDDSSLFEGIVQKHKNMIQVSYDVFKLISDDFLQSLPMSVIKFVIDTLVNFVSQKRNLNISFSSISQFWLVGDYLRVRFNPETLNLSDEKRRSLSEKINNQKLIEIITSSSSHDWELYNGLWIYLLKNLINCTNDDRVEVKNGAVQTFFRIIDSHSVCFPPWDLIFLEVIEPLLTKEWSTEELENETDFINVTLQGLIKLYPEHFKDFKNNTTCAKEWSMLLDFLKRLLSSTSNNTKNAVILNYQTLLKEIITIEDVPSDILKKCCEIFTDYNITYSDLSTNASSKTEYDCIYELITGFPPLYQLISKYDAMTDEFVEKVLLLFNSAIKYPLLPEFVQDKTKPSSMQKAILSGLDIFMTNDSKDTEILILLQLSTISILAFDTREKITKKLGPKLPKASLNRLPTFEAISYMSCSNLRNRIAKIDQFGISTLKAKHILRILKNLAEIIKRKSLITGSESDEIPIWVLASNCFCDLSNKIFKSLQEDAENPLKDNFCDLFINVIVVTLQRINPELDNLTEIDDLNEYSKYREILLENRIIDLFNERQLDTFIYAVWDCSFLYEFDELENALMQDCGTFSELSQKLSSFDFSCIFGSTTNPRFQTKYKCSLECLQDLVNFMLNTNEKLRKLTAPYLSARIALALRRYISDEYLIGRAPIPKLRKTELATLLNGLCVILRGVLDQNSTLGNKQIGVENLQTLSPLILRTIPVSHKMDGLQDKVLELSLGFTKLD", "length": 1636 }, "evidence": [ { "id": "A0A8V0YIJ1", "url": "https://omabrowser.org/oma/group/A0A8V0YIJ1/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q55BA7-1", "protein_name": "Protein MON2 homolog", "gene_name": "mon2", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEKNKSALLSFLEMDLRNISSEARNKLLNIKEASERGILYIKYLQEQSATPEILLQNLKSKSDEILKPFLMALESKNQKMISLAIGSVLKLISHSAISNSSIPSILSKMQLLIDVGSDESIQLKVLQGLLVLITTVPDIHDEELSQLLVLCFRLHGSKNTSIQSTSSATLPQIIRIIFDRVSVEMNTANKEILSSPVTTKLINSKSSDNITLSNNNNQDDSSSSSLSTTSDSTTTTKNDDNTGTTTPTTTTTENTDTKTTTTVTETTDTKTTTATDNQSPQLKSSPSNTNVVQQHQQHNKNKSWSNLKPSAKDAYLLLQDLCYITGSDSPEWLPHTTTISRASGLDFIEMILSVHYDIFFKLEEFKNLLKDKICPLLIKNFKFKMDFYHTVRLIRVITQFISKFSSIMVTESDVLLTKTIKMMDLDQPIWTQILALESFRVYSEDPNLLRLFFKNYDKDNNSAKIFETMTIAIGKYVQNLYGLDSSHFVLVQTSKNRLLDLLWQSEVPLIKESYIISVCTECINGIVNAVSKINNPDNSAQQYSDSLEIFTQMANSCWVSILGGISMLLGKTNDEALIQMVLKSLQSFTNTCGDLHLSAPRDALLTCLCKTTTLPSFELLNSNLNLNATTTTTTTTNTNTINNINNINNINNTNNTNNSNNINNTNINTNNINNSEQQQQQQQQQIQSPISSTSTSSNIISSQQSTPSNSLTPQQLSQNNKDGQISINTMEEKLSNFYPTTKNILSVKILFNIAHCMGSLLDESWILVLETLETWNRFLESFLKKKENSNNTQTTTGTGNTINGNNNNNSGGNKSGDNIILPNPSSLSIANNNNINNNNENTSSPKETSSPRTIGSSEVPILMNSMDNLFKSSSQLDLRSCQYLLEALGKLCTQSFNLKSFNSTPNMFGISKLRETALANLYRIDTIWPLISDHIIDAGNHRNPLFRKYSVEFLNSIIKSTISLQQSQQLLQLQKEKLLSQQQQQQQEKEKEKDNSSLNSESNEDQSSDLTNSPVSTTTTTTTTTTTTTTSTINILNSNLSSINSQFIENYEFEKELLELDKNQIQLEFFTTLEELSFSTSNDTKEKVLESINSILSTSGQSLTTSWPIILSILLRMSKCNEKRFISLSFSSLELICNEFLSNLTPECLALTIELIESFVSQKADINISLTGSSGLLTDLTYFLANENSIKTSKYQVSDGKAIDPVKESHSQCRFTKTLNSRIRPSISESSPFFKEKNKSLIDRMWLCSFNSMKTLCIDVRPAIRNGVVVSLFQILTTYFHLFEKELLDVILWSILFPLIQEIKSFSEKADQERIDSDLGGGVMLLVHHSRNTAQKQWDETQVLSIGGMVRIFKTFFDQLFTLPTFDAAWSTLLNHLQTESKSSSKEVSLTSLSFIHEIVNTPSIIDPSHPQLAESIWECLLHLSPKLFDPQNSVPKSLSVYIKVFTDLFNKTRPQLNHAQMNRALEIIFPMGLFIGDSSTVLSNPQTHAIQLIKSLPPITVDIFPSVISILLKYISIGINMVSPPFTPTSATCDFIFPPQTPITKDLVYYSTITEQSIDLIYELFSHSSTTDEMRSLVFEDIIKVLGASMLTKYQKYHSTIWKLSVSNLIKLLPSGLLAINIDSNHLNDIKRNIIWTELIDSIQTFILHERPNHQISPEKRLEEDQYDIDLINAISKEMVGFSGIKVERVSIIRDRLVEILQEGSVLSAHGREKVAQSCYRNMFSICSTTNNNNNNNNKNDNNNNNNTDDNDGNQASESIEIAKVVLPVVLKRCKDVLTRFVIDERQSGNYPLPRYRLSEISFILKEIYELQLQSGVYQPLNNSTTIIKPECKRPHLLELYTILCDCICTSEKEIKELLKNIFLIISKEFLNL", "length": 1874 }, "evidence": [ { "id": "A0A8V0YIJ1", "url": "https://omabrowser.org/oma/group/A0A8V0YIJ1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q7Z3U7-1", "protein_name": "Protein MON2 homolog", "gene_name": "MON2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSGTSSPEAVKKLLENMQSDLRALSLECKKKFPPVKEAAESGIIKVKTIAARNTEILAALKENSSEVVQPFLMGCGTKEPKITQLCLAAIQRLMSHEVVSETAAGNIINMLWQLMENSLEELKLLQTVLVLLTTNTVVHDEALSKAIVLCFRLHFTKDNITNNTAAATVRQVVTVVFERMVAEDERHRDIIEQPVLVQGNSNRRSVSTLKPCAKDAYMLFQDLCQLVNADAPYWLVGMTEMTRTFGLELLESVLNDFPQVFLQHQEFSFLLKERVCPLVIKLFSPNIKFRQGSSTSSSPAPVEKPYFPICMRLLRVVSVLIKQFYSLLVTECEIFLSLLVKFLDADKPQWLRAVAVESIHRFCVQPQLLRSFCQSYDMKQHSTKVFRDIVNALGSFIQSLFLVPPTGNPATSNQAGNNNLGGSVSAPANSGMVGIGGGVTLLPAFEYRGTWIPILTITVQGSAKATYLEMLDKVEPPTIPEGYAMSVAFHCLLDLVRGITSMIEGELGELETECQTTTEEGSSPTQSTEQQDLQSTSDQMDKEIVSRAVWEEMVNACWCGLLAALSLLLDASTDEAATENILKAELTMAALCGRLGLVTSRDAFITAICKGSLPPHYALTVLNTTTAATLSNKSYSVQGQSVMMISPSSESHQQVVAVGQPLAVQPQGTVMLTSKNIQCMRTLLNLAHCHGAVLGTSWQLVLATLQHLVWILGLKPSSGGALKPGRAVEGPSTVLTTAVMTDLPVISNILSRLFESSQYLDDVSLHHLINALCSLSLEAMDMAYGNNKEPSLFAVAKLLETGLVNMHRIEILWRPLTGHLLEVCQHPNSRMREWGAEALTSLIKAGLTFNHDPPLSQNQRLQLLLLNPLKEMSNINHPDIRLKQLECVLQILQSQGDSLGPGWPLVLGVMGAIRNDQGESLIRTAFQCLQLVVTDFLPTMPCTCLQIVVDVAGSFGLHNQELNISLTSIGLLWNISDYFFQRGETIEKELNKEEAAQQKQAEEKGVVLNRPFHPAPPFDCLWLCLYAKLGELCVDPRPAVRKSAGQTLFSTIGAHGTLLQHSTWHTVIWKVLFHLLDRVRESSTTADKEKIESGGGNILIHHSRDTAEKQWAETWVLTLAGVARIFNTRRYLLQPLGDFSRAWDVLLDHIQSAALSKNNEVSLAALKSFQEILQIVSPVRDSDKPETPPVVNVPVPVLIGPISGMSRPFVRTDSIGEKLGRYSSSEPPIVTDELEDLNLWWAAWNTWYRIGSESTKPPITFDKLTFIPSQPFLTALIQIFPALYQHIKTGFNMDDLQKLGVILHSAISVPISSDASPFILPSYTEAVLTSLQEAVLTALDVLQKAICVGPENMQIMYPAIFDQLLAFVEFSCKPPQYGQLETKHIANAKYNQIQLFAPAEWVALNYVPFAERSLEVVVDLYQKTACHKAVVNEKVLQNIIKTLRVPLSLKYSCPSESTWKLAVSSLLRVLSIGLPVARQHASSGKFDSMWPELANTFEDFLFTKSIPPDNLSIQEFQRNENIDVEVVQLISNEILPYANFIPKEFVGQIMTMLNKGSIHSQSSSFTEAEIDIRLREEFSKMCFETLLQFSFSNKVTTPQEGYISRMALSVLLKRSQDVLHRYIEDERLSGKCPLPRQQVTEIIFVLKAVSTLIDSLKKTQPENVDGNTWAQVIALYPTLVECITCSSSEVCSALKEALVPFKDFMQPPASRVQNGES", "length": 1717 }, "evidence": [ { "id": "A0A8V0YIJ1", "url": "https://omabrowser.org/oma/group/A0A8V0YIJ1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q80TL7-1", "protein_name": "Protein MON2 homolog", "gene_name": "Mon2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSCTNSPEAVKKLLENMQSDLRALSLECKKKFPPVKEAAESGIIKVKTIAARNTEILAALKENSSEVVQPFLMGCGTKEPKITQLCLAAIQRLMSHEVVSETAAGNIINMLWQLMENSLEELKLLQTVLVLLTTNTVVHDEALSKAIVLCFRLHFTKDNITNNTAAATVRQVVTVVFERMVAEDDRHRDIEPPVPIQGNSNRRSVSTLRPCAKDAYMLFQDLCQLVNADAPYWLVGMTEMTRTFGLELLESVLNDFPQVFLQHQEFSFLLKERVCPLVIKLFSPNIKFRQGSSTSSSPAPVEKPYFPICMRLLRVVSVLIKQFYSLLVTECEIFLSLLVKFLDSDKPQWLRAVAVESIHRLCVQPQLLRSFCQSYDMKQHSTKVFRDIVNALGSFIQSLFLVPPTGNPATANQAGNNNAGGPASAPANSGVVGVGGGVTLLPAFEYRGAWIPILTVTVQGSAKATYLEMLDKVEPPTIPEGYAMSVAFHCLLDLVRGITTMIEGELGEVEAEGPSVTEGASSQSSERRDEQAASDPMDQETVSRAVWEEMVSACWCGLLAALSLLLDASTDEAATENILKAELTMAALCGRLGLVTSRDAFITAICKGSLPPHYALTVLNATTAATLSNKSYSIQGQSVMMISPSSESHQQVVAVGQPLAVQPQGTVMLTSKNIQCMRTLLNLAHCHGAVLGTSWQLVLATLQHLVWILGLKPSSGGALKPGRAVEGPSTVLTTAVMTDLPVISNILSRLFESSQYLDDVSLHHLINALCSLSLEAMDMAYGNNKEPSLFAVAKLLETGLVNMHRIEILWRPLTGHLLEKVCQHPNSRMREWGAEALTSLIRAGLTFSHEPPLPQNQRLQLLLLNPLKEMSNINHPDIRLKQLECVLQILQSQGDSLGPGWPLVLGVMGAIRNDQGESLIRTAFQCLQLVVTDFLPTMPCSCLQIVVDVAGSFGLHNQELNISLTSIGLLWNISDYFFQRGETIEKELNKEEAAQQKQAEEKGVSLNRPFHPAPPFDCLWLCLYAKLGELCVDPRPAVRKSAGQTLFSTIGAHGTLLQHSTWHTVIWKVLFHLLDRVRESSTTADKEKIESGGGNILIHHSRDTAEKQWAETWVLTLAGVARIFNTRRYLLQPLGDFSRAWDVLLDHIQSAALSKNNEVSLAALKSFQEILQIVSPVRDSEKPEPPAVSVPVPVLLGNLSGPGLSRPFVRTDSIGEKLGRCGSETPVVTDELEDLKLWWAAWNTWHRTGSESTEPPSSVDELTFIPSQPFLTALVQIFPALYQHIKAGFSMADLQKLGVILHSAVSVPISSDASPFILPSYTEAVLTSLQEAVLTALDVLQKAICVGPENMQIMYPAIFDQLLAFVEFSCKPPQYGQLETKHIANAKYNQIQLFAPAEWVALNYVPFAERSLEVVVDLYQKTACHKAVVNEKVLQNIIKTLRVPLSLKYSCPSESTWKLAVASLLKVLSIGLPVARQHASSGKFDSMWPELASTLEDFLFTKSIPPDNLSIQEFQRNESIDVEVVQLISAEILPYANLIPKAFVGQMMTMLNKGSIHSQPCSFTEAEIDIRLREEFSKMCFETLLQFSFSNKVTTPQEGYISRMALSVLLKRSQDVLHRYIEDERLSGKCPLPRQQVTEIIFVLKAVSTLIDSLKKTQPENVDGNTWSQVIALYPTLVECITCSSSDVGSALKEALAPFKDFMQPPASRVQNGES", "length": 1715 }, "evidence": [ { "id": "A0A8V0YIJ1", "url": "https://omabrowser.org/oma/group/A0A8V0YIJ1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VLT1-1", "protein_name": "Protein MON2 homolog", "gene_name": "mon2", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSFVGGGGCGGQDVHKFVEALQADFKTLSLETKKKYPQIKEACEEAISKLCTAGSSQQNSVYYTVNQILYPLVQGCETKDLKIIKFCLGMMQRLITQQVVDQKGALYITNALWTLMENNIEEVKVLQTVTLLLTTNTVVHGDTLAKALVLCFRLHYAKNPTIVNTAGATIRQLVSLVFERVYLEKDSVSSLQQQQSSGSPAEGEGGNQDVQTFASDAFLLFQDLVQLVNADQPYWLLGMTEMTRTFGLELLEAVLTNFSAVFHESNDFRLLLKERVCALVIKLFSPNVKHRQLPAPSNGNAPVPAEKPYFPISMRLLRLVAILIQKYHTILVTECEIFLSLIIKFLDPDKPAWQRALALEVIHKLVTRSSLIAFFCKSYDLKNHATNIVHDMIAAMGSYIRYSLINASAMLNGQQNGVANSLTAMSGSNQCGFMFRGAYLPLVATYAPGVSKAVYLEMLDKIDASNIPDSYGISVGHAILLDMTRSIGGVIQRTPELHPSHNTAVITEEEHKPLCLQLVNSSWSALLSAFIPLVETSIDEATTENILKAMQNYAALCGMLEQLQPRDAFIMAMCRASFPPHYAMSIFANTTQSDGDLRCHTRSGSQDLSSQFINSCSGDAGDFRPQIVAVGTPLPSASLPHSVMQAPVMLTNKNLQCMRAILFLAHNNGGILGTSWHIVLQTLQHLVWILGLKPSTGGSLQAMPKPAVEANVGIQTAVMADLPVLSQMLSQLFESSQYLDDVALHHLIDALCKLSHEAMELAYANREPSLFAVAKLLETGLVNMPRIKVLWRPLTNHLLEVCQHRHIRMREWGVEAITYLVKSALQFKHKTPLKENMELQTMLLSPLSELSTVLHADVRQRQLDCVLQILNTAGEILSFGWPAIIEIIGAVNEHHGEPLIRTAFQCLQLVITDFLTVMPWRCLPLCISTAAKFGSQTQELNISLTAIGLMWNISDFFNQNQDKLMSTQLQDVSILPDFPGTVKMPQFDKLWMCLYAKLGELCVDLRPAVRKSAGQTLFSTISAHGSLLNPPTWQALVWQVLFPLLDNVRALSSSASNEKVDASGNILIHHSRNTAQKQWAETQVLTLSGVCRVFNTKRELLQMLGDFERAWSLILEFIQNAALSKNGEVSLAALKSLQEIMYHNTAERTERALKDPQTAQEQDEEIWTIAWNIWLSIGMESTKMSTSTSAKLQQQNSNGAETQEDFYIPSQAFLTALIQIFPAIFQHIQVKFTAADFDKFCTVLTNAVCIPVQTDAVPYIMSTVSDTLLTPLHDGILDCMELIQKEATKPDSHISQLIPAIFRQLLIFSKFACAPPTFQQSVEHKYAKSSGHYANNASVEVVSMNYIPFGEKSISICVKLYQTTATEDSVVQEQILHDIVKALRTPLAMKYKCLSSSTWKLAISSLISVLHTGLKVARAKPQHFASLWDDLADTLDKFLFPASVCTIEDRGLEEIVLDETIDCQVIELLRDEVLPHSHEMPHQFIMQIVVLLNKGSIHSASDTNICYESDWKLREIFAKTCFETLLQFSLLEDHANTNNNRLNANVLTAGAAGAGGKDFAGRLAVTALLHRFQEVLKRFNDDERQSGKCPLPRFRLSEISFVLKAIATLVVSMKKAPASKVNKPAWDQLIGLYPYLVDCTTTTSPEVSRSLREALLQYTDLLQAPRSCSAATSNDNVIQSNGQE", "length": 1684 }, "evidence": [ { "id": "A0A8V0YIJ1", "url": "https://omabrowser.org/oma/group/A0A8V0YIJ1/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIJ1" } ], "pmid": "" }, { "name": "retrograde transport, endosome to Golgi", "id": "GO:0042147", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042147", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIJ1" } ], "pmid": "" }, { "name": "protein targeting to vacuole", "id": "GO:0006623", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006623", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIJ1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIJ1" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIJ1" } ], "pmid": "" }, { "name": "early endosome membrane", "id": "GO:0031901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031901", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIJ1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "guanyl-nucleotide exchange factor activity", "id": "GO:0005085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005085", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIJ1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1193, "end_pos": 1195, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1513, "end_pos": 1515, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1522, "end_pos": 1524, "annotation": "n_glycosylation_sequon" }, { "start_pos": 159, "end_pos": 161, "annotation": "n_glycosylation_sequon" }, { "start_pos": 162, "end_pos": 164, "annotation": "n_glycosylation_sequon" }, { "start_pos": 408, "end_pos": 410, "annotation": "n_glycosylation_sequon" }, { "start_pos": 414, "end_pos": 416, "annotation": "n_glycosylation_sequon" }, { "start_pos": 419, "end_pos": 421, "annotation": "n_glycosylation_sequon" }, { "start_pos": 457, "end_pos": 459, "annotation": "n_glycosylation_sequon" }, { "start_pos": 624, "end_pos": 626, "annotation": "n_glycosylation_sequon" }, { "start_pos": 63, "end_pos": 65, "annotation": "n_glycosylation_sequon" }, { "start_pos": 875, "end_pos": 877, "annotation": "n_glycosylation_sequon" }, { "start_pos": 964, "end_pos": 966, "annotation": "n_glycosylation_sequon" }, { "start_pos": 975, "end_pos": 977, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YIJ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIJ1" }, { "id": "PF16206", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16206" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Mon2 C-terminal", "eco_id": "ECO_0000259", "start_pos": 935, "end_pos": 1711, "start_aa": "Thr", "end_aa": "Pro", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0YIJ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIJ1" }, { "id": "PF09324", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09324" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Mon2/Sec7/BIG1-like HDS", "eco_id": "ECO_0000259", "start_pos": 852, "end_pos": 931, "start_aa": "His", "end_aa": "Gln", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0YIJ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIJ1" }, { "id": "PF12783", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12783" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Mon2/Sec7/BIG1-like HUS", "eco_id": "ECO_0000259", "start_pos": 212, "end_pos": 385, "start_aa": "Cys", "end_aa": "Val", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0YIJ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIJ1" }, { "id": "PF16213", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16213" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Mon2/Sec7/BIG1-like dimerisation and cyclophilin-binding", "eco_id": "ECO_0000259", "start_pos": 9, "end_pos": 184, "start_aa": "Ala", "end_aa": "Asp", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1193, "end_pos": 1195 }, { "start_pos": 1513, "end_pos": 1515 }, { "start_pos": 1522, "end_pos": 1524 }, { "start_pos": 159, "end_pos": 161 }, { "start_pos": 162, "end_pos": 164 }, { "start_pos": 408, "end_pos": 410 }, { "start_pos": 414, "end_pos": 416 }, { "start_pos": 419, "end_pos": 421 }, { "start_pos": 457, "end_pos": 459 }, { "start_pos": 624, "end_pos": 626 }, { "start_pos": 63, "end_pos": 65 }, { "start_pos": 875, "end_pos": 877 }, { "start_pos": 964, "end_pos": 966 }, { "start_pos": 975, "end_pos": 977 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YG89-1", "uniprot_ac": "A0A8V0YG89", "uniprot_id": "A0A8V0YG89_CHICK", "mass": { "chemical_mass": 48187.0, "monoisotopic_mass": 48187.0 }, "refseq": {}, "gene_names": [ { "name": "RNF38", "type": "recommended", "evidence": [ { "id": "A0A8V0YG89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG89" } ] } ], "protein_names": [ { "name": "Ring finger protein 38", "type": "synonym", "evidence": [ { "id": "A0A8V0YG89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG89/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YG89", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG89" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RNF38", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG89", "locus": { "chromosome": "Z", "start_pos": 52669204, "end_pos": 52571910, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012095", "url": "https://www.ensembl.org/id/ENSGALG00010012095" } ] } } ], "crossref": [ { "id": "A0A8V0YG89", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YG89", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd16679", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16679", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001841", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001841", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y7U3", "url": "https://www.orthodb.org/?gene=A0A8V0Y7U3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YCU2", "url": "https://www.orthodb.org/?gene=A0A8V0YCU2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YE28", "url": "https://www.orthodb.org/?gene=A0A8V0YE28", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YE33", "url": "https://www.orthodb.org/?gene=A0A8V0YE33", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YG89", "url": "https://www.orthodb.org/?gene=A0A8V0YG89", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YL06", "url": "https://www.orthodb.org/?gene=A0A8V0YL06", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YL10", "url": "https://www.orthodb.org/?gene=A0A8V0YL10", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46171", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46171", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46171:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46171:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13639", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13639", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0Y7U3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y7U3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y7U3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y7U3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YCU2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCU2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YCU2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCU2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YE28", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE28", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YE28-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE28-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YE33", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE33", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YE33-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE33-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YG89", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG89", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YG89-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG89-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YL06", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL06", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YL06-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL06-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YL10", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL10", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YL10-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL10-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRPWDMTSNRQPPLARPNQHHFSGERCNTPARNRRSPPVRRQRTRRDRLSRHNSISLDENYHHLSYGQQQAIEEPRAFRPPNVSPRMLRPAVHPPQQNAVMVDIHDQGTVPVSYTVTTMAPHGIPLCTGQHIPACSTQQVPACSVVFSGQHLPVCSVPPPMLQACSVQHLPVPYAAFPPLISSDPFLLHPPHLSPHHPPHLPPPGQFVPFQAQQSRSPFQRIENEVELLGEHLPVGGFTYPPSAHPPTLPPSAPLQFLTHDPLHQEVSFGVPYPPFMPRRLTGRSRYRSQQPIPPHPYHPSLLPYVLSMFPVPPAVGRAFSIELDVEDGEVENYEALLNLAERLGEAKPRGLTKADIEQLPSYRFNPNNHQSEQTLCVVCMCDFESRQLLRVLPCNHEFHAKCVDKWLKANRTCPICRADASEVHRD", "length": 427, "header": "tr|A0A8V0YG89-1|A0A8V0YG89_CHICK Isoform 1 of Ring finger protein 38 OS=Gallus gallus OX=9031 GN=RNF38 PE=4 SV=1 CANONICAL=A0A8V0YG89-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Y7U3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG89/entry#A0A8V0Y7U3-1", "sequence": { "sequence": "MERTTEEQTVPQQPMEGTAEEQAVPQQPTEGTMGEQAVPPQPMERTVGEQADPQQPMEGTMGEQAVPLQPMEGKVGEQAVPLQPMEGTVGEQAVPLQPMEGTVGEQAVPLQPVEGNVGEQAVPLQPIEGTMGEQSVPLQPTEGTVGEQAVPLQPMEETVGEQAVPLQPMEETVGEQAVPLQPMEDRSRADLHTEAREGPHSGAGSIATSFQCQSIHQDHICNDDGDKSEDGPSPKRQRLSHSVFDYTTASPASSPPMRPWDMTSNRQPPLARPNQHHFSGERCNTPARNRRSPPVRRQRTRRDRLSRHNSISLDENYHHLSYGQQQAIEEPRAFRPPNVSPRMLRPAVHPPQQNAVMVDIHDQIHQGTVPVSYTVTTMAPHGIPLCTGQHIPACSTQQVPACSVVFSGQHLPVCSVPPPMLQACSVQHLPVPYAAFPPLISSDPFLLHPPHLSPHHPPHLPPPGQFVPFQAQQSRSPFQRIENEVELLGEHLPVGGFTYPPSAHPPTLPPSAPLQFLTHDPLHQEVSFGVPYPPFMPRRLTGRSRYRSQQPIPPHPYHPSLLPYVLSMFPVPPAVGRAFSIELDVEDGEVENYEALLNLAERLGEAKPRGLTKADIEQLPSYRFNPNNHQSEQTLCVVCMCDFESRQLLRVLPCNHEFHAKCVDKWLKANRTCPICRADASEVHRD", "length": 686, "header": "tr|A0A8V0Y7U3-1|A0A8V0Y7U3_CHICK Computationally mapped isoform of Ring finger protein 38 OS=Gallus gallus OX=9031 GN=RNF38 PE=4 SV=1 CANONICAL=A0A8V0YG89-1" }, "locus": { "chromosome": "Z", "start_pos": 52668058, "end_pos": 52629334, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028988.1", "url": "https://www.ensembl.org/id/ENSGALT00010028988.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016747.1", "url": "https://www.ensembl.org/id/ENSGALP00010016747.1" } ] } }, { "isoform_ac": "A0A8V0YCU2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG89/entry#A0A8V0YCU2-1", "sequence": { "sequence": "MSQVLADVHLCCCFCFQMLPSVSVGAQGAMVMGVFGRAGSCILEKGSIATSFQCQSIHQDHICNDDGDKSEDGPSPKRQRLSHSVFDYTTASPASSPPMRPWDMTSNRQPPLARPNQHHFSGERCNTPARNRRSPPVRRQRTRRDRLSRHNSISLDENYHHLSYGQQQAIEEPRAFRPPNVSPRMLRPAVHPPQQNAVMVDIHDQIHQGTVPVSYTVTTMAPHGIPLCTGQHIPACSTQQVPACSVVFSGQHLPVCSVPPPMLQACSVQHLPVPYAAFPPLISSDPFLLHPPHLSPHHPPHLPPPGQFVPFQAQQSRSPFQRIENEVELLGEHLPVGGFTYPPSAHPPTLPPSAPLQFLTHDPLHQEVSFGVPYPPFMPRRLTGRSRYRSQQPIPPHPYHPSLLPYVLSMFPVPPAVGRAFSIELDVEDGEVENYEALLNLAERLGEAKPRGLTKADIEQLPSYRFNPNNHQSEQTLCVVCMCDFESRQLLRVLPCNHEFHAKCVDKWLKANRTCPICRADASEVHRD", "length": 528, "header": "tr|A0A8V0YCU2-1|A0A8V0YG89_CHICK Computationally mapped isoform of Ring finger protein 38 OS=Gallus gallus OX=9031 GN=RNF38 PE=4 SV=1 CANONICAL=A0A8V0YG89-1" }, "locus": { "chromosome": "Z", "start_pos": 52668058, "end_pos": 52584396, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028992.1", "url": "https://www.ensembl.org/id/ENSGALT00010028992.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016751.1", "url": "https://www.ensembl.org/id/ENSGALP00010016751.1" } ] } }, { "isoform_ac": "A0A8V0YE28-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG89/entry#A0A8V0YE28-1", "sequence": { "sequence": "MGAPVMLSGSIATSFQCQSIHQDHICNDDGDKSEDGPSPKRQRLSHSVFDYTTASPASSPPMRPWDMTSNRQPPLARPNQHHFSGERCNTPARNRRSPPVRRQRTRRDRLSRHNSISLDENYHHLSYGQQQAIEEPRAFRPPNVSPRMLRPAVHPPQQNAVMVDIHDQIHQGTVPVSYTVTTMAPHGIPLCTGQHIPACSTQQVPACSVVFSGQHLPVCSVPPPMLQACSVQHLPVPYAAFPPLISSDPFLLHPPHLSPHHPPHLPPPGQFVPFQAQQSRSPFQRIENEVELLGEHLPVGGFTYPPSAHPPTLPPSAPLQFLTHDPLHQEVSFGVPYPPFMPRRLTGRSRYRSQQPIPPHPYHPSLLPYVLSMFPVPPAVGRAFSIELDVEDGEVENYEALLNLAERLGEAKPRGLTKADIEQLPSYRFNPNNHQSEQTLCVVCMCDFESRQLLRVLPCNHEFHAKCVDKWLKANRTCPICRADASEVHRD", "length": 491, "header": "tr|A0A8V0YE28-1|A0A8V0YG89_CHICK Computationally mapped isoform of Ring finger protein 38 OS=Gallus gallus OX=9031 GN=RNF38 PE=4 SV=1 CANONICAL=A0A8V0YG89-1" }, "locus": { "chromosome": "Z", "start_pos": 52668058, "end_pos": 52597815, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028990.1", "url": "https://www.ensembl.org/id/ENSGALT00010028990.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016749.1", "url": "https://www.ensembl.org/id/ENSGALP00010016749.1" } ] } }, { "isoform_ac": "A0A8V0YE33-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG89/entry#A0A8V0YE33-1", "sequence": { "sequence": "MSSIATSFQCQSIHQDHICNDDGDKSEDGPSPKRQRLSHSVFDYTTASPASSPPMRPWDMTSNRQPPLARPNQHHFSGERCNTPARNRRSPPVRRQRTRRDRLSRHNSISLDENYHHLSYGQQQAIEEPRAFRPPNVSPRMLRPAVHPPQQNAVMVDIHDQIHQGTVPVSYTVTTMAPHGIPLCTGQHIPACSTQQVPACSVVFSGQHLPVCSVPPPMLQACSVQHLPVPYAAFPPLISSDPFLLHPPHLSPHHPPHLPPPGQFVPFQAQQSRSPFQRIENEVELLGEHLPVGGFTYPPSAHPPTLPPSAPLQFLTHDPLHQEVSFGVPYPPFMPRRLTGRSRYRSQQPIPPHPYHPSLLPYVLSMFPVPPAVGRAFSIELDVEDGEVENYEALLNLAERLGEAKPRGLTKADIEQLPSYRFNPNNHQSEQTLCVVCMCDFESRQLLRVLPCNHEFHAKCVDKWLKANRTCPICRADASEVHRD", "length": 484, "header": "tr|A0A8V0YE33-1|A0A8V0YG89_CHICK Computationally mapped isoform of Ring finger protein 38 OS=Gallus gallus OX=9031 GN=RNF38 PE=4 SV=1 CANONICAL=A0A8V0YG89-1" }, "locus": { "chromosome": "Z", "start_pos": 52668058, "end_pos": 52591387, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028995.1", "url": "https://www.ensembl.org/id/ENSGALT00010028995.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016754.1", "url": "https://www.ensembl.org/id/ENSGALP00010016754.1" } ] } }, { "isoform_ac": "A0A8V0YG89-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG89/entry#A0A8V0YG89-1", "sequence": { "sequence": "MRPWDMTSNRQPPLARPNQHHFSGERCNTPARNRRSPPVRRQRTRRDRLSRHNSISLDENYHHLSYGQQQAIEEPRAFRPPNVSPRMLRPAVHPPQQNAVMVDIHDQGTVPVSYTVTTMAPHGIPLCTGQHIPACSTQQVPACSVVFSGQHLPVCSVPPPMLQACSVQHLPVPYAAFPPLISSDPFLLHPPHLSPHHPPHLPPPGQFVPFQAQQSRSPFQRIENEVELLGEHLPVGGFTYPPSAHPPTLPPSAPLQFLTHDPLHQEVSFGVPYPPFMPRRLTGRSRYRSQQPIPPHPYHPSLLPYVLSMFPVPPAVGRAFSIELDVEDGEVENYEALLNLAERLGEAKPRGLTKADIEQLPSYRFNPNNHQSEQTLCVVCMCDFESRQLLRVLPCNHEFHAKCVDKWLKANRTCPICRADASEVHRD", "length": 427, "header": "tr|A0A8V0YG89-1|A0A8V0YG89_CHICK Isoform 1 of Ring finger protein 38 OS=Gallus gallus OX=9031 GN=RNF38 PE=4 SV=1 CANONICAL=A0A8V0YG89-1" }, "locus": { "chromosome": "Z", "start_pos": 52668058, "end_pos": 52647219, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028986.1", "url": "https://www.ensembl.org/id/ENSGALT00010028986.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016745.1", "url": "https://www.ensembl.org/id/ENSGALP00010016745.1" } ] } }, { "isoform_ac": "A0A8V0YL06-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG89/entry#A0A8V0YL06-1", "sequence": { "sequence": "MERTTEEQTVPQQPMEGTAEEQAVPQQPTEGTMGEQAVPPQPMERTVGEQADPQQPMEGTMGEQAVPLQPMEGKVGEQAVPLQPMEGTVGEQAVPLQPMEGTVGEQAVPLQPVEGNVGEQAVPLQPIEGTMGEQSVPLQPTEGTVGEQAVPLQPMEETVGEQAVPLQPMEETVGEQAVPLEPMEETVGEQAVPLQPMEDRSRADLHTEAREGPHSGAGSIATSFQCQSIHQDHICNDDGDKSEDGPSPKRQRLSHSVFDYTTASPASSPPMRPWDMTSNRQPPLARPNQHHFSGERCNTPARNRRSPPVRRQRTRRDRLSRHNSISLDENYHHLSYGQQQAIEEPRAFRPPNVSPRMLRPAVHPPQQNAVMVDIHDQIHQGTVPVSYTVTTMAPHGIPLCTGQHIPACSTQQVPACSVVFSGQHLPVCSVPPPMLQACSVQHLPVPYAAFPPLISSDPFLLHPPHLSPHHPPHLPPPGQFVPFQAQQSRSPFQRIENEVELLGEHLPVGGFTYPPSAHPPTLPPSAPLQFLTHDPLHQEVSFGVPYPPFMPRRLTGRSRYRSQQPIPPHPYHPSLLPYVLSMFPVPPAVGRAFSIELDVEDGEVENYEALLNLAERLGEAKPRGLTKADIEQLPSYRFNPNNHQSEQTLQIVPAQFAELMLQKCIVIRVTNLRAQIWFGCSWSCVYMNYLLNLPMWLPAFSFTQKGQWTLLCTV", "length": 714, "header": "tr|A0A8V0YL06-1|A0A8V0YL06_CHICK Computationally mapped isoform of Ring finger protein 38 OS=Gallus gallus OX=9031 GN=RNF38 PE=4 SV=1 CANONICAL=A0A8V0YG89-1" }, "locus": { "chromosome": "Z", "start_pos": 52668200, "end_pos": 52629334, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028989.1", "url": "https://www.ensembl.org/id/ENSGALT00010028989.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016748.1", "url": "https://www.ensembl.org/id/ENSGALP00010016748.1" } ] } }, { "isoform_ac": "A0A8V0YL10-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG89/entry#A0A8V0YL10-1", "sequence": { "sequence": "MGAVWPHGTNPPAVRGAEGTGGPRGNRAVVWLAAGSVCKHTCRVLAKSCAQKAGKRISVSSSILPSVCRHQIKGSIATSFQCQSIHQDHICNDDGDKSEDGPSPKRQRLSHSVFDYTTASPASSPPMRPWDMTSNRQPPLARPNQHHFSGERCNTPARNRRSPPVRRQRTRRDRLSRHNSISLDENYHHLSYGQQQAIEEPRAFRPPNVSPRMLRPAVHPPQQNAVMVDIHDQIHQGTVPVSYTVTTMAPHGIPLCTGQHIPACSTQQVPACSVVFSGQHLPVCSVPPPMLQACSVQHLPVPYAAFPPLISSDPFLLHPPHLSPHHPPHLPPPGQFVPFQAQQSRSPFQRIENEVELLGEHLPVGGFTYPPSAHPPTLPPSAPLQFLTHDPLHQEVSFGVPYPPFMPRRLTGRSRYRSQQPIPPHPYHPSLLPYVLSMFPVPPAVGRAFSIELDVEDGEVENYEALLNLAERLGEAKPRGLTKADIEQLPSYRFNPNNHQSEQTLCVVCMCDFESRQLLRVLPCNHEFHAKCVDKWLKANRTCPICRADASEVHRD", "length": 556, "header": "tr|A0A8V0YL10-1|A0A8V0YL10_CHICK Computationally mapped isoform of Ring finger protein 38 OS=Gallus gallus OX=9031 GN=RNF38 PE=4 SV=1 CANONICAL=A0A8V0YG89-1" }, "locus": { "chromosome": "Z", "start_pos": 52668058, "end_pos": 52575462, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028994.1", "url": "https://www.ensembl.org/id/ENSGALT00010028994.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016753.1", "url": "https://www.ensembl.org/id/ENSGALP00010016753.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YG89", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG89" } ], "pmid": "" }, { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YG89", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG89" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YG89", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG89" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YG89", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG89" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 411, "end_pos": 413, "annotation": "n_glycosylation_sequon" }, { "start_pos": 82, "end_pos": 84, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YG89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG89" }, { "id": "PS50089", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50089" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RING-type", "eco_id": "ECO_0000259", "start_pos": 377, "end_pos": 418, "start_aa": "Cys", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 411, "end_pos": 413 }, { "start_pos": 82, "end_pos": 84 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YGD8-1", "uniprot_ac": "A0A8V0YGD8", "uniprot_id": "A0A8V0YGD8_CHICK", "mass": { "chemical_mass": 31438.0, "monoisotopic_mass": 31438.0 }, "refseq": {}, "gene_names": [ { "name": "LOC121108245", "type": "recommended", "evidence": [ { "id": "A0A8V0YGD8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGD8" } ] }, { "name": "MBD2", "type": "recommended", "evidence": [ { "id": "A0A8V0YGD8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGD8" } ] }, { "name": "LOC121108245", "type": "synonym", "evidence": [ { "id": "A0A8V0YGD8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGD8" } ] } ], "protein_names": [ { "name": "Methyl-CpG binding domain protein 2", "type": "synonym", "evidence": [ { "id": "A0A8V0YGD8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGD8/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGD8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGD8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MBD2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGD8", "locus": { "chromosome": "W", "start_pos": 561876, "end_pos": 601520, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012112", "url": "https://www.ensembl.org/id/ENSGALG00010012112" } ] } } ], "crossref": [ { "id": "A0A8V0YGD8", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YGD8", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd01396", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01396", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001739", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001739", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016177", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016177", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR025884", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025884", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032343", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032343", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YCY2", "url": "https://www.orthodb.org/?gene=A0A8V0YCY2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YDP8", "url": "https://www.orthodb.org/?gene=A0A8V0YDP8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YGD8", "url": "https://www.orthodb.org/?gene=A0A8V0YGD8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YLT4", "url": "https://www.orthodb.org/?gene=A0A8V0YLT4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12396", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12396", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12396:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12396:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01429", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01429", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14048", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14048", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16564", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16564", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-427413", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-427413", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-73728", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-73728", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9937850", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9937850", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9940951", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9940951", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YCY2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCY2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YCY2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCY2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YDP8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDP8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YDP8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDP8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YGD8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGD8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YGD8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGD8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLT4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLT4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLT4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLT4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDKQGRTDCPALPPGWKKEEVIRKSGLSAGKSDVYYFSPSGKKFRSKPQLARYLGNAVDLSCFDFRTGKMMPSKLQKNKQRLRNESLHPNKGKPDLNTALPIRQTASIFKQPVTKVTNHPDNKVRSDPQRLADQPRQLFWEKRLRGLSASDVGQEILRAMELPRGLQALGPVPDDVTLLSAVASALHVGSVPVTGQLSSAAEKNPAVWLNSSQPLCRAFVVTDDDIRKQEERVRRVRKKLEEALLAGDPAGSRGQRSPFWGQRVHIWGQRSHIWGQRSHLG", "length": 281, "header": "tr|A0A8V0YGD8-1|A0A8V0YGD8_CHICK Isoform 1 of Methyl-CpG binding domain protein 2 OS=Gallus gallus OX=9031 GN=MBD2 PE=1 SV=1 CANONICAL=A0A8V0YGD8-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YCY2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGD8/entry#A0A8V0YCY2-1", "sequence": { "sequence": "MDKQGRTDCPALPPGWKKEEVIRKSGLSAGKSDVYYFSPSGKKFRSKPQLARYLGNAVDLSCFDFRTGKMMPSKLQKNKQRLRNESLHPNKGKPDLNTALPIRQTASIFKQPVTKVTNHPDNKVRSDPQRLADQPRQLFWEKRLRGLSASDVGQEILRAMELPRGLQALGPVPDDVTLLSAVASALHVGSVPVTGQLSSAAEKNPAVWLNSSQPLCRAFVVTDDDIRKQEERVRRVRKKLEEALLAGDPAGSRLGGLGRGQRSPSVHFLGGGG", "length": 273, "header": "tr|A0A8V0YCY2-1|A0A8V0YGD8_CHICK Computationally mapped isoform of Methyl-CpG binding domain protein 2 OS=Gallus gallus OX=9031 GN=MBD2 PE=1 SV=1 CANONICAL=A0A8V0YGD8-1" }, "locus": { "chromosome": "Z", "start_pos": 201809, "end_pos": 169159, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029382.1", "url": "https://www.ensembl.org/id/ENSGALT00010029382.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017066.1", "url": "https://www.ensembl.org/id/ENSGALP00010017066.1" } ] } }, { "isoform_ac": "A0A8V0YDP8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGD8/entry#A0A8V0YDP8-1", "sequence": { "sequence": "MGFFMGFLGLGIWDFGDFSSLWVSVWSNPSGKKFRSKPQLARYLGNAVDLSCFDFRTGKMMPSKLQKNKQRLRNESLHPNKGKPDLNTALPIRQTASIFKQPVTKVTNHPDNKVRSDPQRLADQPRQLFWEKRLRGLSASDVGQEILRAMELPRGLQALGPVPDDVTLLSAVASALHVGSVPVTGQLSSAAEKNPAVWLNSSQPLCRAFVVTDDDIRKQEERVRRVRKKLEEALLAGDPAGSRGQDE", "length": 247, "header": "tr|A0A8V0YDP8-1|A0A8V0YGD8_CHICK Computationally mapped isoform of Methyl-CpG binding domain protein 2 OS=Gallus gallus OX=9031 GN=MBD2 PE=1 SV=1 CANONICAL=A0A8V0YGD8-1" }, "locus": { "chromosome": "Z", "start_pos": 194972, "end_pos": 169258, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029369.1", "url": "https://www.ensembl.org/id/ENSGALT00010029369.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017056.1", "url": "https://www.ensembl.org/id/ENSGALP00010017056.1" } ] } }, { "isoform_ac": "A0A8V0YGD8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGD8/entry#A0A8V0YGD8-1", "sequence": { "sequence": "MDKQGRTDCPALPPGWKKEEVIRKSGLSAGKSDVYYFSPSGKKFRSKPQLARYLGNAVDLSCFDFRTGKMMPSKLQKNKQRLRNESLHPNKGKPDLNTALPIRQTASIFKQPVTKVTNHPDNKVRSDPQRLADQPRQLFWEKRLRGLSASDVGQEILRAMELPRGLQALGPVPDDVTLLSAVASALHVGSVPVTGQLSSAAEKNPAVWLNSSQPLCRAFVVTDDDIRKQEERVRRVRKKLEEALLAGDPAGSRGQRSPFWGQRVHIWGQRSHIWGQRSHLG", "length": 281, "header": "tr|A0A8V0YGD8-1|A0A8V0YGD8_CHICK Isoform 1 of Methyl-CpG binding domain protein 2 OS=Gallus gallus OX=9031 GN=MBD2 PE=1 SV=1 CANONICAL=A0A8V0YGD8-1" }, "locus": { "chromosome": "W", "start_pos": 601377, "end_pos": 561877, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029042.1", "url": "https://www.ensembl.org/id/ENSGALT00010029042.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016801.1", "url": "https://www.ensembl.org/id/ENSGALP00010016801.1" } ] } }, { "isoform_ac": "A0A8V0YLT4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGD8/entry#A0A8V0YLT4-1", "sequence": { "sequence": "MGFLGLGIWDFLGVFFLLCPHSPSGKKFRSKPQLARYLGNAVDLSCFDFRTGKMMPSKLQKNKQRLRNESLHPNKGKPDLNTALPIRQTASIFKQPVTKVTNHPDNKVRSDPQRLADQPRQLFWEKRLRGLSASDVGQEILRAMELPRGLQALGPVPDDVTLLSAVASALHVGSVPVTGQLSSAAEKNPAVWLNSSQPLCRAFVVTDDDIRKQEERVRRVRKKLEEALLAGDPAGSRGQDE", "length": 241, "header": "tr|A0A8V0YLT4-1|A0A8V0YLT4_CHICK Computationally mapped isoform of Methyl-CpG binding domain protein 2 OS=Gallus gallus OX=9031 GN=LOC121108245 PE=1 SV=1 CANONICAL=A0A8V0YGD8-1" }, "locus": { "chromosome": "Z", "start_pos": 191690, "end_pos": 169258, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029372.1", "url": "https://www.ensembl.org/id/ENSGALT00010029372.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017058.1", "url": "https://www.ensembl.org/id/ENSGALP00010017058.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-427413", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-427413", "resource": "Reactome", "description": "NoRC negatively regulates rRNA expression" }, { "id": "R-GGA-73728", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-73728", "resource": "Reactome", "description": "RNA Polymerase I Promoter Opening" }, { "id": "R-GGA-9937850", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9937850", "resource": "Reactome", "description": "NuRD complex assembly" }, { "id": "R-GGA-9940951", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9940951", "resource": "Reactome", "description": "Interaction of NuRD complexes with transcription factors" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGD8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGD8" } ], "pmid": "" }, { "name": "methyl-CpG binding", "id": "GO:0008327", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008327", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGD8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGD8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGD8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGD8" } ], "pmid": "" }, { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGD8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGD8" } ], "pmid": "" }, { "name": "DNA methylation-dependent constitutive heterochromatin formation", "id": "GO:0006346", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006346", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGD8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGD8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGD8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGD8" } ], "pmid": "" }, { "name": "histone deacetylase complex", "id": "GO:0000118", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000118", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGD8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGD8" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGD8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGD8" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGD8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGD8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 210, "end_pos": 212, "annotation": "n_glycosylation_sequon" }, { "start_pos": 84, "end_pos": 86, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YGD8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGD8" }, { "id": "PS50982", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50982" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "MBD", "eco_id": "ECO_0000259", "start_pos": 2, "end_pos": 70, "start_aa": "Asp", "end_aa": "Met", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 210, "end_pos": 212 }, { "start_pos": 84, "end_pos": 86 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YF55-1", "uniprot_ac": "A0A8V0YF55", "uniprot_id": "A0A8V0YF55_CHICK", "mass": { "chemical_mass": 59080.0, "monoisotopic_mass": 59080.0 }, "refseq": {}, "gene_names": [ { "name": "TCP11X2", "type": "recommended", "evidence": [ { "id": "A0A8V0YF55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF55" } ] } ], "protein_names": [ { "name": "T-complex 11 family X2", "type": "synonym", "evidence": [ { "id": "A0A8V0YF55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF55/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YF55", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF55" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TCP11X2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF55", "locus": { "chromosome": "1", "start_pos": 53927653, "end_pos": 53944028, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010011912", "url": "https://www.ensembl.org/id/ENSGALG00010011912" } ] } } ], "crossref": [ { "id": "A0A8V0YF55", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YF55", "database": "AlphaFoldDB", "categories": [] }, { "id": "425052", "url": "https://www.ncbi.nlm.nih.gov/gene/425052", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR008862", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008862", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YBN4", "url": "https://www.orthodb.org/?gene=A0A8V0YBN4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YCY9", "url": "https://www.orthodb.org/?gene=A0A8V0YCY9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YF55", "url": "https://www.orthodb.org/?gene=A0A8V0YF55", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12832", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12832", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12832:SF17", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12832:SF17", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05794", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05794", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YBN4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBN4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YBN4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBN4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YCY9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCY9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YCY9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCY9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YF55", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF55", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YF55-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF55-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLFNHKSCLLHQLKGSTMPLNDDQNSDSDSSRLSESTASSSDSEYSRQSFNSDSSSKPSSPASASPPKMVTFDELMAAARNLSNLTLAHEIAVNANFCIKHEDHPQNSLAGTVKQIVHKAFWDHLESELNEDPPEYEHAIKLFEEIKEILLSFLTPGANRIQNQICEVLDTDLIRQQAEHNAVDIHGLANYIINTMGKLCAPIRDNDIKQLKATENIVELLRQIFHVLDLMKMDVANYTIQSLRPYLRRNLVDYERTKFQEILEETPSALDLTTEWIKESIEDELSSISNESSSSPGADHSSKSSISPTLVLNNGYLKLLQWDYHKTIPETLITDEVRLQELREKLNQLKIIACVCLITNNMVGAAIVNVPDFASQLKRISVPLLEGMSKKTFDLKEALNAIGIQICIKVNESLAERDLPTLNTEMQNNLMGQIASIVEENNPVSSLIDKRIQLFMKSLLALPSFRKCMPTLPGGLSVIQPEMELVGSQFASIVEFNKQVYGPFYANILKKLLFPEAAIGKAGIEAPSN", "length": 529, "header": "tr|A0A8V0YF55-1|A0A8V0YF55_CHICK Isoform 1 of T-complex 11 family X2 OS=Gallus gallus OX=9031 GN=TCP11X2 PE=3 SV=1 CANONICAL=A0A8V0YF55-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YBN4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF55/entry#A0A8V0YBN4-1", "sequence": { "sequence": "MKTTHRTAGTVKQIVHKAFWDHLESELNEDPPEYEHAIKLFEEIKEILLSFLTPGANRIQNQICEVLDTDLIRQQAEHNAVDIHGLANYIINTMGKLCAPIRDNDIKQLKATENIVELLRQIFHVLDLMKMDVANYTIQSLRPYLRRNLVDYERTKFQEILEETPSALDLTTEWIKESIEDELSSISNESSSSPGADHSSKSSISPTLVLNNGYLKLLQWDYHKTIPETLITDEVRLQELREKLNQLKIIACVCLITNNMVGAAIVNVPDFASQLKRISVPLLEGMSKKTFDLKEALNAIGIQICIKVNESLAERDLPTLNTEMQNNLMGQIASIVEENNPVSSLIDKRIQLFMKSLLALPSFRKCMPTLPGGLSVIQPEMELVGSQFASIVEFNKQVYGPFYANILKKLLFPEAAIGKAGIEAPSN", "length": 427, "header": "tr|A0A8V0YBN4-1|A0A8V0YBN4_CHICK Computationally mapped isoform of T-complex 11 family X2 OS=Gallus gallus OX=9031 GN=TCP11X2 PE=3 SV=1 CANONICAL=A0A8V0YF55-1" }, "locus": { "chromosome": "1", "start_pos": 53936958, "end_pos": 53930095, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028501.1", "url": "https://www.ensembl.org/id/ENSGALT00010028501.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016356.1", "url": "https://www.ensembl.org/id/ENSGALP00010016356.1" } ] } }, { "isoform_ac": "A0A8V0YCY9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF55/entry#A0A8V0YCY9-1", "sequence": { "sequence": "MPLNDDQNSDSDSSRLSESTASSSDSEYSRQSFNSDSSSKPSSPASSPPKMVTFDELMAAARNLSNLTLAHEIAVNANFCIKHEDHPQNSLAGTVKQIVHKAFWDHLESELNEDPPEYEHAIKLFEEIKEILLSFLTPGANRIQNQICEVLDTDLIRQQAEHNAVDIHGLANYIINTMGKLCAPIRDNDIKQLKATENIVELLRQIFHVLDLMKMDVANYTIQSLRPYLRRNLVDYERTKFQEILEETPSALDLTTEWIKESIEDELSSISNESSSSPGADHSSKSSISPTLVLNNGYLKLLQWDYHKTIPETLITDEVRLQELREKLNQLKIIACVCLITNNMVGAAIVNVPDFASQLKRISVPLLEGMSKKTFDLKEALNAIGIQICIKVNESLAERDLPTLNTEMQNNLMGQIASIVEENNPVSSLIDKRIQLFMKSLLALPSFRKCMPTLPGGLSVIQPEMELVGSQFASIVEFNKQVFSPNTWFPFKTAGILHTEIG", "length": 502, "header": "tr|A0A8V0YCY9-1|A0A8V0YF55_CHICK Computationally mapped isoform of T-complex 11 family X2 OS=Gallus gallus OX=9031 GN=TCP11X2 PE=3 SV=1 CANONICAL=A0A8V0YF55-1" }, "locus": { "chromosome": "1", "start_pos": 53938505, "end_pos": 53928915, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028493.1", "url": "https://www.ensembl.org/id/ENSGALT00010028493.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016349.1", "url": "https://www.ensembl.org/id/ENSGALP00010016349.1" } ] } }, { "isoform_ac": "A0A8V0YF55-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF55/entry#A0A8V0YF55-1", "sequence": { "sequence": "MLFNHKSCLLHQLKGSTMPLNDDQNSDSDSSRLSESTASSSDSEYSRQSFNSDSSSKPSSPASASPPKMVTFDELMAAARNLSNLTLAHEIAVNANFCIKHEDHPQNSLAGTVKQIVHKAFWDHLESELNEDPPEYEHAIKLFEEIKEILLSFLTPGANRIQNQICEVLDTDLIRQQAEHNAVDIHGLANYIINTMGKLCAPIRDNDIKQLKATENIVELLRQIFHVLDLMKMDVANYTIQSLRPYLRRNLVDYERTKFQEILEETPSALDLTTEWIKESIEDELSSISNESSSSPGADHSSKSSISPTLVLNNGYLKLLQWDYHKTIPETLITDEVRLQELREKLNQLKIIACVCLITNNMVGAAIVNVPDFASQLKRISVPLLEGMSKKTFDLKEALNAIGIQICIKVNESLAERDLPTLNTEMQNNLMGQIASIVEENNPVSSLIDKRIQLFMKSLLALPSFRKCMPTLPGGLSVIQPEMELVGSQFASIVEFNKQVYGPFYANILKKLLFPEAAIGKAGIEAPSN", "length": 529, "header": "tr|A0A8V0YF55-1|A0A8V0YF55_CHICK Isoform 1 of T-complex 11 family X2 OS=Gallus gallus OX=9031 GN=TCP11X2 PE=3 SV=1 CANONICAL=A0A8V0YF55-1" }, "locus": { "chromosome": "1", "start_pos": 53939536, "end_pos": 53930095, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028486.1", "url": "https://www.ensembl.org/id/ENSGALT00010028486.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016345.1", "url": "https://www.ensembl.org/id/ENSGALP00010016345.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YF55", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF55" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nuclear speck", "id": "GO:0016607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016607", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YF55", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF55" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 237, "end_pos": 239, "annotation": "n_glycosylation_sequon" }, { "start_pos": 290, "end_pos": 292, "annotation": "n_glycosylation_sequon" }, { "start_pos": 411, "end_pos": 413, "annotation": "n_glycosylation_sequon" }, { "start_pos": 81, "end_pos": 83, "annotation": "n_glycosylation_sequon" }, { "start_pos": 84, "end_pos": 86, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 237, "end_pos": 239 }, { "start_pos": 290, "end_pos": 292 }, { "start_pos": 411, "end_pos": 413 }, { "start_pos": 81, "end_pos": 83 }, { "start_pos": 84, "end_pos": 86 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YGJ1-1", "uniprot_ac": "A0A8V0YGJ1", "uniprot_id": "A0A8V0YGJ1_CHICK", "mass": { "chemical_mass": 53909.0, "monoisotopic_mass": 53909.0 }, "refseq": { "ac": "XP_015134147", "name": "cis-aconitate decarboxylase-like isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015134147" }, "gene_names": [ { "name": "ACOD1L", "type": "recommended", "evidence": [ { "id": "A0A8V0YGJ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGJ1" } ] }, { "name": "ACOD1L", "type": "synonym", "evidence": [ { "id": "XP_015134147", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015134147" } ] } ], "protein_names": [ { "name": "Cis-aconitate decarboxylase", "type": "recommended", "evidence": [ { "id": "A0A8V0YGJ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGJ1/entry#names_and_taxonomy" } ] }, { "name": "4.1.1.6", "type": "synonym", "evidence": [ { "id": "A0A8V0YGJ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGJ1/entry#names_and_taxonomy" } ] }, { "name": "Aconitate decarboxylase 1", "type": "synonym", "evidence": [ { "id": "A0A8V0YGJ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGJ1/entry#names_and_taxonomy" } ] }, { "name": "Aconitate decarboxylase", "type": "synonym", "evidence": [ { "id": "A0A8V0YGJ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGJ1/entry#names_and_taxonomy" } ] }, { "name": "Cis-aconitic acid decarboxylase", "type": "synonym", "evidence": [ { "id": "A0A8V0YGJ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGJ1/entry#names_and_taxonomy" } ] }, { "name": "Immune-responsive gene 1 protein", "type": "synonym", "evidence": [ { "id": "A0A8V0YGJ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGJ1/entry#names_and_taxonomy" } ] }, { "name": "cis-aconitate decarboxylase-like isoform X2", "type": "synonym", "evidence": [ { "id": "XP_015134147", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015134147" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052535.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015134147.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015134147", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015134147" } ] }, { "annotation": "Cis-aconitate decarboxylase that catalyzes production of itaconate and is involved in the inhibition of the inflammatory response. Acts as a negative regulator of the Toll-like receptors (TLRs)-mediated inflammatory innate response by stimulating the tumor necrosis factor alpha-induced protein TNFAIP3 expression via reactive oxygen species (ROS) in LPS-tolerized macrophages. Involved in antimicrobial response of innate immune cells; ACOD1-mediated itaconic acid production contributes to the antimicrobial activity of macrophages by generating itaconate, leading to alkylation of proteins, such as TFEB. Involved in antiviral response following infection by flavivirus in neurons: ACOD1-mediated itaconate production inhibits the activity of succinate dehydrogenase, generating a metabolic state in neurons that suppresses replication of viral genomes. Plays a role in the embryo implantation.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YD38", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD38#function" }, { "database": "UniProtKB", "id": "ARBA00055971", "url": "https://www.uniprot.org/uniprotkb/ARBA00055971#function" }, { "database": "UniProtKB", "id": "A0A8V0YGJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGJ1#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGJ1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ACOD1L", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGJ1", "locus": {} } ], "crossref": [ { "id": "A0A8V0YGJ1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YGJ1", "database": "AlphaFoldDB", "categories": [] }, { "id": "422307", "url": "https://www.ncbi.nlm.nih.gov/gene/422307", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR005656", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005656", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036148", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036148", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042183", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042183", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042188", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042188", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045336", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045336", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045337", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045337", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:422307", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422307", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MHPATVI", "url": "https://omabrowser.org/oma/group/MHPATVI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YD38", "url": "https://www.orthodb.org/?gene=A0A8V0YD38", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YGJ1", "url": "https://www.orthodb.org/?gene=A0A8V0YGJ1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16943", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16943", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16943:SF14", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16943:SF14", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03972", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03972", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF19305", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19305", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015134147", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015134147", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "15253", "url": "https://www.rhea-db.org/rhea/15253", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YD38", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD38", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YD38-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD38-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YGJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGJ1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YGJ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGJ1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVFLTLQKSQRFLASSRQVHKTAAHVVARSAPEETVTSSFASFIHAVRPEHLSKIVRYRSKRMILDSIGVGLVGSTTHVFDIALKYCLELYSSVAVSNVYGKPGVKLSPTLAAFTNGVATHSMDFDDTWHPATHPSGAVLPALLAASQMLPPNSKPNGLDFLLAFNVGLEVQGRLMHFSTEAHNIPKRFHPPSVVGTMGSAAATAKLLCLNMTQCTHALGIAASLAGAPMANAATQAKPLHIGNATRLGFEAALLAARGMEANPFILDDISGCSGFSAFYSIYQPRSLSTPNEHHEFLLEKQDIAFKRFPAHLGMHWVVDAALSVRNLFINYAGSFSPSLIRTIVLKVPVSKYINRPFPNSEHEARHSFQFNACTALLDGEVGLSSFTESSIHRQELRELLHKVVVEHPEDNVANFDKMYGEVAVLLKSGDVLTGKCDTFYGHWRKPLSRESLLKKFRSNASHVLPEEKVETIITMVDNLENLSDSSHLACSL", "length": 493, "header": "tr|A0A8V0YGJ1-1|A0A8V0YGJ1_CHICK Isoform 1 of Cis-aconitate decarboxylase OS=Gallus gallus OX=9031 GN=ACOD1L PE=3 SV=1 CANONICAL=A0A8V0YGJ1-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YD38-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGJ1/entry#A0A8V0YD38-1", "sequence": { "sequence": "MGAAQFRQIFLQPLQSNRSSQFPPPRGHWRSHLQCKGDAHREGTDLVCRRVSKLLSGTDSYSDPFCRAAARGDFFSVSHSNDDILSCVYKWISDSPALVVARSAPEETVTSSFASFIHAVRPEHLSKIVRYRSKRMILDSIGVGLVGSTTHVFDIALKYCLELYSSVAVSNVYGKPGVKLSPTLAAFTNGVATHSMDFDDTWHPATHPSGAVLPALLAASQMLPPNSKPNGLDFLLAFNVGLEVQGRLMHFSTEAHNIPKRFHPPSVVGTMGSAAATAKLLCLNMTQCTHALGIAASLAGAPMANAATQAKPLHIGNATRLGFEAALLAARGMEANPFILDDISGCSGFSAFYSIYQPRSLSTPNEHHEFLLEKQDIAFKRFPAHLGMHWVVDAALSVRNLFINYAGSFSPSLIRTIVLKVPVSKYINRPFPNSEHEARHSFQFNACTALLDGEVGLSSFTESSIHRQELRELLHKVVVEHPEDNVANFDKMYGEVAVLLKSGDVLTGKCDTFYGHWRKPLSRESLLKKFRSNASHVLPEEKVETIITMVDNLENLSDSSHLACSL", "length": 566, "header": "tr|A0A8V0YD38-1|A0A8V0YGJ1_CHICK Computationally mapped isoform of Cis-aconitate decarboxylase OS=Gallus gallus OX=9031 GN=ACOD1L PE=3 SV=1 CANONICAL=A0A8V0YGJ1-1" }, "locus": { "chromosome": "4", "start_pos": 11295118, "end_pos": 11290900, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029109.1", "url": "https://www.ensembl.org/id/ENSGALT00010029109.1" }, { 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} ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "4.1.1.6", "ec_name": "cis-aconitate + H(+) = itaconate + CO2.", "evidence": [ { "id": "4.1.1.6", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.1.6" }, { "id": "4.1.1.6", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=4.1.1.6" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 211, "end_pos": 213 }, { "start_pos": 244, "end_pos": 246 }, { "start_pos": 460, "end_pos": 462 }, { "start_pos": 482, "end_pos": 484 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { 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This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015146754", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015146754" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFI3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFI3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SCUBE1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFI3", "locus": { "chromosome": "1", "start_pos": 68646881, "end_pos": 68847610, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010011981", "url": "https://www.ensembl.org/id/ENSGALG00010011981" } ] } } ], "crossref": [ { "id": "A0A8V0YFI3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YFI3", "database": 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Classification" ] }, { "id": "IPR049883", "url": "https://www.ebi.ac.uk/interpro/entry/IPR049883", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052071", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052071", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:418228", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418228", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "NQETCST", "url": "https://omabrowser.org/oma/group/NQETCST/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y753", "url": "https://www.orthodb.org/?gene=A0A8V0Y753", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YDB7", "url": "https://www.orthodb.org/?gene=A0A8V0YDB7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YFI3", "url": "https://www.orthodb.org/?gene=A0A8V0YFI3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YFJ3", "url": "https://www.orthodb.org/?gene=A0A8V0YFJ3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YKB3", "url": "https://www.orthodb.org/?gene=A0A8V0YKB3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24046", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24046", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24046:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24046:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00431", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00431", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07645", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07645", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07699", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07699", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12662", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12662", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12947", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12947", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14670", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14670", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-1474228", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1474228", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_015146754", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015146754", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Y753", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y753", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y753-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y753-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YDB7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDB7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YDB7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDB7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YFI3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFI3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YFI3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFI3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YFJ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFJ3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YFJ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFJ3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YKB3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKB3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YKB3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKB3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGTVCFARRCCLLFALFWAGRLAAGSGSADVDECAEATDDCHIDAICQNTPKSYKCICKPGYKGEGKQCEDIDECENDFYNGGCVHECINIPGNYRCTCYDGFMLAHDGHNCLDVDECQDNNGGCQQICVNTMGSYECQCKEGFFLSDNQHTCIHRSIEGMNCMNKDHGCAHICRETPKGGVACECRPGFELAKNQKDCKLTCNYGNGGCQHTCDDTDTGPVCGCHQKYALHSDGRTCIEKDEAAIESSEYNATSVADVDKRVKRRLLMETCAVNNGGCDRTCKDTATGVRCSCPVGFTLQPDGKTCKDIDECLVNNGGCDHFCRNTVGSFECSCQKGYKLLTDERTCQDIDECSFERTCDHTCINYPGSFECLCHKGYTLYGLTHCGDIDECSISNGSCDYGCLNTMGSYECVCPPGKKLHWNKKDCIEMVKCLPNAKPAPKAQLVCSKTGGIESCFLSCPSNTLFVPDSENSYTLSCGVPVQQGKAQQKRNATLPSCADSLAPPIKQKARFKIKDAKCHLRPRSKEKTKDAGKQAVLGGQFPCTDNCQVTFVNLKCDSSKKKRRGRKSPSKEVSHITAEFEVEMKSEEVSDTCNIDCVRKRMEQKLQTAIKTLRKSINKQQFYIQFSGTEYEVAQKPAKATEGHEACSTGQVLQDGKCVTCSTGTFYSGEHNQCIPCSPGTYQDTEGQLTCEPCPSNDGQGVAGARNVSECGGQCSPGHYSSDGFKPCRVCPLGTYQPEPGRTLCFPCGGGLVTKYEGAVSFQDCETKVHCSPGHYYNSTTHRCIRCPVGTYQPEFGQNYCITCPGNTSTDFDGSTNVTHCKNQHCGGELGDYTGYIESPNYPGDYPANVECIWNINPPPKRRILIVVPEIFLPIEDECGDVLVMRKSASPTSITTYETCQTYERPIAFTSRSRKLWIQFKSNEGNSGKGFQVPYVTYDEDYQQLIEDIVRDGRLYASENHQEILKDKKLIKALFDVLAHPQNYFKYTAQESKEMFPRSFIKLLRSKVSRFLRPYK", "length": 1018, "header": "tr|A0A8V0YFI3-1|A0A8V0YFI3_CHICK Isoform 1 of Signal peptide, CUB domain and EGF like domain containing 1 OS=Gallus gallus OX=9031 GN=SCUBE1 PE=4 SV=1 CANONICAL=A0A8V0YFI3-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Y753-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFI3/entry#A0A8V0Y753-1", "sequence": { "sequence": "MGTVCFARRCCLLFALFWAGRLAAGSGSADVDECAEATDDCHIDAICQNTPKSYKCICKPGYKGEGKQCEDIDECENDFYNGGCVHECINIPGNYRCTCYDGFMLAHDGHNCLDVDECQDNNGGCQQICVNTMGSYECQCKEGFFLSDNQHTCIHRSIEGMNCMNKDHGCAHICRETPKGGVACECRPGFELAKNQKDCKLTCNYGNGGCQHTCDDTDTGPVCGCHQKYALHSDGRTCIDIDECLVNNGGCDHFCRNTVGSFECSCQKGYKLLTDERTCQDIDECSFERTCDHTCINYPGSFECLCHKGYTLYGLTHCGDIDECSISNGSCDYGCLNTMGSYECVCPPGKKLHWNKKDCIEMVKCLPNAKPAPKAQLVCSKTGGIESCFLSCPSNTLFVPDSENSYTLSCGVPVQQGKAQQKRNATLPSCADSLAPPIKQKARFKIKDAKCHLRPRSKEKTKDAGKQAVLGGQFPCTDNCQVTFVNLKCDSSKKKRRGRKSPSKEVSHITAEFEVEMKSEEVSDTCNIDCVRKRMEQKLQTAIKTLRKSINKQQFYIQFSGTEYEVAQKPAKATEGHEACSTGQVLQDGKCVTCSTGTFYSGEHNQCIPCSPGTYQDTEGQLTCEPCPSNDGQGVAGARNVSECGGQCSPGHYSSDGFKPCRVCPLGTYQPEPGRTLCFPCGGGLVTKYEGAVSFQDCETKVHCSPGHYYNSTTHRCIRCPVGTYQPEFGQNYCITCPGNTSTDFDGSTNVTHCKNQHCGGELGDYTGYIESPNYPGDYPANVECIWNINPPPKRRILIVVPEIFLPIEDECGDVLVMRKSASPTSITTYETCQTYERPIAFTSRSRKLWIQFKSNEGNSGKGFQVPYVTYDEDYQQLIEDIVRDGRLYASENHQEILKDKKLIKALFDVLAHPQNYFKYTAQESKEMFPRSFIKLLRSKVSRFLRPYK", "length": 949, "header": "tr|A0A8V0Y753-1|A0A8V0Y753_CHICK Computationally mapped isoform of Signal peptide, CUB domain and EGF like domain containing 1 OS=Gallus gallus OX=9031 GN=SCUBE1 PE=4 SV=1 CANONICAL=A0A8V0YFI3-1" }, "locus": { "chromosome": "1", "start_pos": 68847575, "end_pos": 68647063, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028690.1", "url": "https://www.ensembl.org/id/ENSGALT00010028690.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016496.1", "url": "https://www.ensembl.org/id/ENSGALP00010016496.1" } ] } }, { "isoform_ac": "A0A8V0YDB7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFI3/entry#A0A8V0YDB7-1", "sequence": { "sequence": "MGTVCFARRCCLLFALFWAGRLAAGSGSADVDECAEATDDCHIDAICQNTPKSYKCICKPGYKGEGKQCEDIDECENDFYNGGCVHECINIPGNYRCTCYDGFMLAHDGHNCLDVDECQDNNGGCQQICVNTMGSYECQCKEGFFLSDNQHTCIHRSIEGMNCMNKDHGCAHICRETPKGGVACECRPGFELAKNQKDCKLTCNYGNGGCQHTCDDTDTGPVCGCHQKYALHSDGRTCIETCAVNNGGCDRTCKDTATGVRCSCPVGFTLQPDGKTCKDIDECLVNNGGCDHFCRNTVGSFECSCQKGYKLLTDERTCQDIDECSFERTCDHTCINYPGSFECLCHKGYTLYGLTHCGDIDECSISNGSCDYGCLNTMGSYECVCPPGKKLHWNKKDCIEMVKCLPNAKPAPKAQLVCSKTGGIESCFLSCPSNTLFVPDSENSYTLSCGVPVQQGKAQQKRNATLPSCADSLAPPIKQKARFKIKDAKCHLRPRSKEKTKDAGKQAVLGGQFPCTDNCQVTFVNLKCDSSKKKRRGRKSPSKEVSHITAEFEVEMKSEEVSDTCNIDCVRKRMEQKLQTAIKTLRKSINKQQFYIQFSGTEYEVAQKPAKATEGHEACSTGQVLQDGKCVTCSTGTFYSGEHNQCIPCSPGTYQDTEGQLTCEPCPSNDGQGVAGARNVSECGGQCSPGHYSSDGFKPCRVCPLGTYQPEPGRTLCFPCGGGLVTKYEGAVSFQDCETKVHCSPGHYYNSTTHRCIRCPVGTYQPEFGQNYCITCPGNTSTDFDGSTNVTHCKNQHCGGELGDYTGYIESPNYPGDYPANVECIWNINPPPKRRILIVVPEIFLPIEDECGDVLVMRKSASPTSITTYETCQTYERPIAFTSRSRKLWIQFKSNEGNSGKGFQVPYVTYDEDYQQLIEDIVRDGRLYASENHQEILKDKKLIKALFDVLAHPQNYFKYTAQESKEMFPRSFIKLLRSKVSRFLRPYK", "length": 988, "header": "tr|A0A8V0YDB7-1|A0A8V0YFI3_CHICK Computationally mapped isoform of Signal peptide, CUB domain and EGF like domain containing 1 OS=Gallus gallus OX=9031 GN=SCUBE1 PE=4 SV=1 CANONICAL=A0A8V0YFI3-1" }, "locus": { "chromosome": "1", "start_pos": 68847575, "end_pos": 68647063, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028683.1", "url": "https://www.ensembl.org/id/ENSGALT00010028683.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016491.1", "url": "https://www.ensembl.org/id/ENSGALP00010016491.1" } ] } }, { "isoform_ac": "A0A8V0YFI3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFI3/entry#A0A8V0YFI3-1", "sequence": { "sequence": "MGTVCFARRCCLLFALFWAGRLAAGSGSADVDECAEATDDCHIDAICQNTPKSYKCICKPGYKGEGKQCEDIDECENDFYNGGCVHECINIPGNYRCTCYDGFMLAHDGHNCLDVDECQDNNGGCQQICVNTMGSYECQCKEGFFLSDNQHTCIHRSIEGMNCMNKDHGCAHICRETPKGGVACECRPGFELAKNQKDCKLTCNYGNGGCQHTCDDTDTGPVCGCHQKYALHSDGRTCIEKDEAAIESSEYNATSVADVDKRVKRRLLMETCAVNNGGCDRTCKDTATGVRCSCPVGFTLQPDGKTCKDIDECLVNNGGCDHFCRNTVGSFECSCQKGYKLLTDERTCQDIDECSFERTCDHTCINYPGSFECLCHKGYTLYGLTHCGDIDECSISNGSCDYGCLNTMGSYECVCPPGKKLHWNKKDCIEMVKCLPNAKPAPKAQLVCSKTGGIESCFLSCPSNTLFVPDSENSYTLSCGVPVQQGKAQQKRNATLPSCADSLAPPIKQKARFKIKDAKCHLRPRSKEKTKDAGKQAVLGGQFPCTDNCQVTFVNLKCDSSKKKRRGRKSPSKEVSHITAEFEVEMKSEEVSDTCNIDCVRKRMEQKLQTAIKTLRKSINKQQFYIQFSGTEYEVAQKPAKATEGHEACSTGQVLQDGKCVTCSTGTFYSGEHNQCIPCSPGTYQDTEGQLTCEPCPSNDGQGVAGARNVSECGGQCSPGHYSSDGFKPCRVCPLGTYQPEPGRTLCFPCGGGLVTKYEGAVSFQDCETKVHCSPGHYYNSTTHRCIRCPVGTYQPEFGQNYCITCPGNTSTDFDGSTNVTHCKNQHCGGELGDYTGYIESPNYPGDYPANVECIWNINPPPKRRILIVVPEIFLPIEDECGDVLVMRKSASPTSITTYETCQTYERPIAFTSRSRKLWIQFKSNEGNSGKGFQVPYVTYDEDYQQLIEDIVRDGRLYASENHQEILKDKKLIKALFDVLAHPQNYFKYTAQESKEMFPRSFIKLLRSKVSRFLRPYK", "length": 1018, "header": "tr|A0A8V0YFI3-1|A0A8V0YFI3_CHICK Isoform 1 of Signal peptide, CUB domain and EGF like domain containing 1 OS=Gallus gallus OX=9031 GN=SCUBE1 PE=4 SV=1 CANONICAL=A0A8V0YFI3-1" }, "locus": { "chromosome": "1", "start_pos": 68847575, "end_pos": 68647063, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028679.1", "url": "https://www.ensembl.org/id/ENSGALT00010028679.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016487.1", "url": "https://www.ensembl.org/id/ENSGALP00010016487.1" } ] } }, { "isoform_ac": "A0A8V0YFJ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFI3/entry#A0A8V0YFJ3-1", "sequence": { "sequence": "MGTVCFARRCCLLFALFWAGRLAAGSGSADVDECAEATDDCHIDAICQNTPKSYKCICKPGYKGEGKQCEDIDECENDFYNGGCVHECINIPGNYRCTCYDGFMLAHDGHNCLDVDECQDNNGGCQQICVNTMGSYECQCKEGFFLSDNQHTCIHRSIEGMNCMNKDHGCAHICRETPKGGVACECRPGFELAKNQKDCKLTCNYGNGGCQHTCDDTDTGPVCGCHQKYALHSDGRTCIETCAVNNGGCDRTCKDTATGVRCSCPVGFTLQPDGKTCKDIDECSFERTCDHTCINYPGSFECLCHKGYTLYGLTHCGDIDECSISNGSCDYGCLNTMGSYECVCPPGKKLHWNKKDCIEMVKCLPNAKPAPKAQLVCSKTGGIESCFLSCPSNTLFVPDSENSYTLSCGVPVQQGKAQQKRNATLPSCADSLAPPIKQKARFKIKDAKCHLRPRSKEKTKDAGKQAVLGGQFPCTDNCQVTFVNLKCDSSKKKRRGRKSPSKEVSHITAEFEVEMKSEEVSDTCNIDCVRKRMEQKLQTAIKTLRKSINKQQFYIQFSGTEYEVAQKPAKATEGHEACSTGQVLQDGKCVTCSTGTFYSGEHNQCIPCSPGTYQDTEGQLTCEPCPSNDGQGVAGARNVSECGGQCSPGHYSSDGFKPCRVCPLGTYQPEPGRTLCFPCGGGLVTKYEGAVSFQDCETKVHCSPGHYYNSTTHRCIRCPVGTYQPEFGQNYCITCPGNTSTDFDGSTNVTHCKNQHCGGELGDYTGYIESPNYPGDYPANVECIWNINPPPKRRILIVVPEIFLPIEDECGDVLVMRKSASPTSITTYETCQTYERPIAFTSRSRKLWIQFKSNEGNSGKGFQVPYVTYDEDYQQLIEDIVRDGRLYASENHQEILKDKKLIKALFDVLAHPQNYFKYTAQESKEMFPRSFIKLLRSKVSRFLRPYK", "length": 947, "header": "tr|A0A8V0YFJ3-1|A0A8V0YFJ3_CHICK Computationally mapped isoform of Signal peptide, CUB domain and EGF like domain containing 1 OS=Gallus gallus OX=9031 GN=SCUBE1 PE=4 SV=1 CANONICAL=A0A8V0YFI3-1" }, "locus": { "chromosome": "1", "start_pos": 68847575, "end_pos": 68647063, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028695.1", "url": "https://www.ensembl.org/id/ENSGALT00010028695.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016499.1", "url": "https://www.ensembl.org/id/ENSGALP00010016499.1" } ] } }, { "isoform_ac": "A0A8V0YKB3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFI3/entry#A0A8V0YKB3-1", "sequence": { "sequence": "MGTVCFARRCCLLFALFWAGRLAAGSGSADVDECAEATDDCHIDAICQNTPKSYKCICKPGYKGEGKQCEDIDECENDFYNGGCVHECINIPGNYRCTCYDGFMLAHDGHNCLDVDECQDNNGGCQQICVNTMGSYECQCKEGFFLSDNQHTCIHRSIEGMNCMNKDHGCAHICRETPKGGVACECRPGFELAKNQKDCKYIDECLVNNGGCDHFCRNTVGSFECSCQKGYKLLTDERTCQDIDECSFERTCDHTCINYPGSFECLCHKGYTLYGLTHCGDIDECSISNGSCDYGCLNTMGSYECVCPPGKKLHWNKKDCIEMVKCLPNAKPAPKAQLVCSKTGGIESCFLSCPSNTLFVPDSENSYTLSCGVPVQQGKAQQKRNATLPSCADSLAPPIKQKARFKIKDAKCHLRPRSKEKTKDAGKQAVLGGQFPCTDNCQVTFVNLKCDSSKKKRRGRKSPSKEVSHITAEFEVEMKSEEVSDTCNIDCVRKRMEQKLQTAIKTLRKSINKQQFYIQFSGTEYEVAQKPAKATEGHEACSTGQVLQDGKCVTCSTGTFYSGEHNQCIPCSPGTYQDTEGQLTCEPCPSNDGQGVAGARNVSECGGQCSPGHYSSDGFKPCRVCPLGTYQPEPGRTLCFPCGGGLVTKYEGAVSFQDCETKVHCSPGHYYNSTTHRCIRCPVGTYQPEFGQNYCITCPGNTSTDFDGSTNVTHCKNQHCGGELGDYTGYIESPNYPGDYPANVECIWNINPPPKRRILIVVPEIFLPIEDECGDVLVMRKSASPTSITTYETCQTYERPIAFTSRSRKLWIQFKSNEGNSGKGFQVPYVTYDEDYQQLIEDIVRDGRLYASENHQEILKDKKLIKALFDVLAHPQNYFKYTAQESKEMFPRSFIKLLRSKVSRFLRPYK", "length": 910, "header": "tr|A0A8V0YKB3-1|A0A8V0YKB3_CHICK Computationally mapped isoform of Signal peptide, CUB domain and EGF like domain containing 1 OS=Gallus gallus OX=9031 GN=SCUBE1 PE=4 SV=1 CANONICAL=A0A8V0YFI3-1" }, "locus": { "chromosome": "1", "start_pos": 68847575, "end_pos": 68647063, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028700.1", "url": "https://www.ensembl.org/id/ENSGALT00010028700.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016503.1", "url": "https://www.ensembl.org/id/ENSGALP00010016503.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:418228", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418228", "resource": "KEGG Pathway" }, { "id": "R-GGA-1474228", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1474228", "resource": "Reactome", "description": "Degradation of the extracellular matrix" } ], "orthologs": [ { "uniprot_canonical_ac": "F1M987-1", "protein_name": "Signal peptide, CUB and EGF-like domain-containing protein 1", "gene_name": "Scube1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGAAAVRWHLCLLLALGARGQLVGGSGLPGAVDVDECSEGTDDCHIDAICQNTPKSYKCLCKPGYKGEGKQCEDIDECENDYYNGGCVHDCINIPGNYRCTCFDGFMLAHDGHNCLDVDECQDNNGGCQQICVNAMGSYECQCHSGFFLSDNQHTCIHRSNEGMNCMNKDHGCAHICRETPKGGVACDCRPGFDLAQNQKDCTLTCNYGNGGCQHSCEDTDTGPMCGCHQKYALHADGRTCIEKDEAAIERSQFNATSVADVDKRVKRRLLMETCAVNNGGCDRTCKDTATGVRCSCPVGFTLQPDGKTCKDINECLMNNGGCDHFCRNTVGSFECGCQKGHKLLTDERTCQDIDECSFERTCDHICINSPGSFQCLCHRGYILYGTTHCGDVDECSMNNGSCDQGCVNTKGSYECVCPPGRRLHWNRKDCVEMSGCLSRSKASAQAQLSCGKVGGVENCFLSCLGQSLFMPDSETSYILSCGVPGLQGKAPPKRNGTSSSVGPGCSDAPTTPIRQKARFKIRDAKCHLRPRSQERAKDTLRHPLLDNCHVTFVTLKCDSSKKRRRGRKSPSKEVSHITAEFEVEMKVEEASGSCEADCMRKRAEQSLQAAIKTLRKSIGRHQFYVQVSGTEYEVAQRPAKAPEGTGTCGIGQILQDGKCVPCAPGTYFSSEPGQCVPCVSGTYQDMEGQLSCTPCPSSEGLGLAGARNVSECGGQCSPGFFSEDGFKPCQACPVGTYQPEPGRTGCFPCGGGLLTKQTGTASFQECEAKVHCSPGHHYNTTTHRCIRCPVGTYQPEFGQNHCISCPGNTSTDFDGSTNVTHCKNQHCGGELGDYTGYIESPNYPGDYPANAECVWHIAPPPKRRILIVVPEIFLPIEDECGDVLVMRKSASPTSVTTYETCQTYERPIAFTSRSRKLWIQFKSNEANSGKGFQVPYVTYDEDYQQLIEDIVRDGRLYASENHQEILKDKKLIKALFDVLAHPQNYFKYTAQESKEMFPRSFIKLLRSKVSRFLRPYK", "length": 1018 }, "evidence": [ { "id": "A0A8V0YFI3", "url": "https://omabrowser.org/oma/group/A0A8V0YFI3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6NZL8-1", "protein_name": "Signal peptide, CUB and EGF-like domain-containing protein 1", "gene_name": "Scube1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGAAAVRWHLYLLLALGARGRLVGGSGLPGAVDVDECSEGTDDCHIDAICQNTPKSYKCLCKPGYKGEGRQCEDIDECENDYYNGGCVHDCINIPGNYRCTCFDGFMLAHDGHNCLDVDECQDNNGGCQQICVNAMGSYECQCHSGFFLSDNQHTCIHRSNEGMNCMNKDHGCAHICRETPKGGVACDCRPGFDLAQNQKDCTLTCNYGNGGCQHSCEDTDTGPMCGCHQKYALHADGRTCIEKDEAAIERSQFNATSVADVDKRVKRRLLMETCAVNNGGCDRTCKDTATGVRCSCPVGFTLQPDGKTCKDINECLMNNGGCDHFCRNTVGSFECGCQKGHKLLTDERTCQDIDECSFERTCDHICINSPGSFQCLCRRGYTLYGTTHCGDVDECSMNNGSCEQGCVNTKGSYECVCPPGRRLHWNQKDCVEMNGCLSRSKASAQAQLSCGKVGGVENCFLSCLGHSLFMPDSESSYILSCGVPGLQGKTLPKRNGTSSSTGPGCSDAPTTPIRQKARFKIRDAKCHLQPRSQERAKDTLRHPLLDNCHVTFVTLKCDSSKKRRRGRKSPSKEVSHITAEFEVEMKVDEASGTCEADCMRKRAEQSLQAAIKILRKSIGRNQFYVQVLGTEYEVAQRPAKALEGTGTCGIGQILQDGKCVPCAPGTYFSGDPGQCMPCVSGTYQDMEGQLSCTPCPSSEGLGLAGARNVSECGGQCSPGYFSADGFKPCQACPVGTYQPEPGRTGCFPCGGGLLTKHTGTASFQDCEAKVHCSPGHHYNTTTHRCIRCPVGTYQPEFGQNHCISCPGNTSTDFDGSTNVTHCKNQHCGGELGDYTGYIESPNYPGDYPANAECVWHIAPPPKRRILIVVPEIFLPIEDECGDVLVMRKSASPTSVTTYETCQTYERPIAFTSRSRKLWIQFKSNEANSGKGFQVPYVTYDEDYQQLIEDIVRDGRLYASENHQEILKDKKLIKALFDVLAHPQNYFKYTAQESKEMFPRSFIKLLRSKVSRFLRPYK", "length": 1018 }, "evidence": [ { "id": "A0A8V0YFI3", "url": "https://omabrowser.org/oma/group/A0A8V0YFI3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8IWY4-1", "protein_name": "Signal peptide, CUB and EGF-like domain-containing protein 1", "gene_name": "SCUBE1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGAAAVRWHLCVLLALGTRGRLAGGSGLPGSVDVDECSEGTDDCHIDAICQNTPKSYKCLCKPGYKGEGKQCEDIDECENDYYNGGCVHECINIPGNYRCTCFDGFMLAHDGHNCLDVDECQDNNGGCQQICVNAMGSYECQCHSGFFLSDNQHTCIHRSNEGMNCMNKDHGCAHICRETPKGGVACDCRPGFDLAQNQKDCTLTCNYGNGGCQHSCEDTDTGPTCGCHQKYALHSDGRTCIETCAVNNGGCDRTCKDTATGVRCSCPVGFTLQPDGKTCKDINECLVNNGGCDHFCRNTVGSFECGCRKGYKLLTDERTCQDIDECSFERTCDHICINSPGSFQCLCHRGYILYGTTHCGDVDECSMSNGSCDQGCVNTKGSYECVCPPGRRLHWNGKDCVETGKCLSRAKTSPRAQLSCSKAGGVESCFLSCPAHTLFVPDSENSYVLSCGVPGPQGKALQKRNGTSSGLGPSCSDAPTTPIKQKARFKIRDAKCHLRPHSQARAKETARQPLLDHCHVTFVTLKCDSSKKRRRGRKSPSKEVSHITAEFEIETKMEEASDTCEADCLRKRAEQSLQAAIKTLRKSIGRQQFYVQVSGTEYEVAQRPAKALEGQGACGAGQVLQDSKCVACGPGTHFGGELGQCVSCMPGTYQDMEGQLSCTPCPSSDGLGLPGARNVSECGGQCSPGFFSADGFKPCQACPVGTYQPEPGRTGCFPCGGGLLTKHEGTTSFQDCEAKVHCSPGHHYNTTTHRCIRCPVGTYQPEFGQNHCITCPGNTSTDFDGSTNVTHCKNQHCGGELGDYTGYIESPNYPGDYPANAECVWHIAPPPKRRILIVVPEIFLPIEDECGDVLVMRKSASPTSITTYETCQTYERPIAFTSRSRKLWIQFKSNEGNSGKGFQVPYVTYDEDYQQLIEDIVRDGRLYASENHQEILKDKKLIKALFDVLAHPQNYFKYTAQESKEMFPRSFIKLLRSKVSRFLRPYK", "length": 988 }, "evidence": [ { "id": "A0A8V0YFI3", "url": "https://omabrowser.org/oma/group/A0A8V0YFI3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFI3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFI3" } ], "pmid": "" }, { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFI3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFI3" } ], "pmid": "" }, { "name": "cell surface", "id": "GO:0009986", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009986", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFI3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFI3" } ], "pmid": "" }, { "name": "external side of plasma membrane", "id": "GO:0009897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009897", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFI3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFI3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFI3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFI3" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFI3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFI3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFI3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFI3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 252, "end_pos": 254, "annotation": "n_glycosylation_sequon" }, { "start_pos": 397, "end_pos": 399, "annotation": "n_glycosylation_sequon" }, { "start_pos": 493, "end_pos": 495, "annotation": "n_glycosylation_sequon" }, { "start_pos": 709, "end_pos": 711, "annotation": "n_glycosylation_sequon" }, { "start_pos": 780, "end_pos": 782, "annotation": "n_glycosylation_sequon" }, { "start_pos": 809, "end_pos": 811, "annotation": "n_glycosylation_sequon" }, { "start_pos": 819, "end_pos": 821, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YFI3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFI3" }, { "id": "PS01180", "database": "PROSITE", "url": "https://prosite.expasy.org/PS01180" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CUB", "eco_id": "ECO_0000259", "start_pos": 828, "end_pos": 940, "start_aa": "Cys", "end_aa": "Tyr", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0YFI3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFI3" }, { "id": "PS50026", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50026" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "EGF-like", "eco_id": "ECO_0000259", "start_pos": 30, "end_pos": 70, "start_aa": "Asp", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 252, "end_pos": 254 }, { "start_pos": 397, "end_pos": 399 }, { "start_pos": 493, "end_pos": 495 }, { "start_pos": 709, "end_pos": 711 }, { "start_pos": 780, "end_pos": 782 }, { "start_pos": 809, "end_pos": 811 }, { "start_pos": 819, "end_pos": 821 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YGZ6-1", "uniprot_ac": "A0A8V0YGZ6", "uniprot_id": "A0A8V0YGZ6_CHICK", "mass": { "chemical_mass": 59446.0, "monoisotopic_mass": 59446.0 }, "refseq": { "ac": "XP_040506617", "name": "coiled-coil domain-containing protein 77 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040506617" }, "gene_names": [ { "name": "CCDC77", "type": "recommended", "evidence": [ { "id": "A0A8V0YGZ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGZ6" } ] }, { "name": "CCDC77", "type": "synonym", "evidence": [ { "id": "XP_040506617", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040506617" } ] } ], "protein_names": [ { "name": "Coiled-coil domain containing 77", "type": "synonym", "evidence": [ { "id": "A0A8V0YGZ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGZ6/entry#names_and_taxonomy" } ] }, { "name": "coiled-coil domain-containing protein 77 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_040506617", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040506617" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040506617", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040506617" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGZ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGZ6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CCDC77", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGZ6", "locus": { "chromosome": "1", "start_pos": 60352296, "end_pos": 60336845, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012242", "url": "https://www.ensembl.org/id/ENSGALG00010012242" } ] } } ], "crossref": [ { "id": "A0A8V0YGZ6", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YGZ6", "database": "AlphaFoldDB", "categories": [] }, { "id": "418149", "url": "https://www.ncbi.nlm.nih.gov/gene/418149", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR037696", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037696", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:418149", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418149", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HLSHMYR", "url": "https://omabrowser.org/oma/group/HLSHMYR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YDN0", "url": "https://www.orthodb.org/?gene=A0A8V0YDN0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YGZ6", "url": "https://www.orthodb.org/?gene=A0A8V0YGZ6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22091", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22091", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22091:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22091:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "XP_040506617", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040506617", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YDN0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDN0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YDN0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDN0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YGZ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGZ6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YGZ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGZ6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSATGGSAGRSSRSRRSRHYKVFVRSMLATPHSSSRHSSSQPQSQGDSTPLPSINERLAFLRPSRELLEYYRKKIADFDEEHEDLVKRLERYKETYDEQHKLQWEVRQREEEIAELQKALSDMQVYLFQEREHVLRLYSENDRLKIRELEDRKKIQHLLALVGTDAGEVTYFHKEPPHKVTVLQRPARSRDSHDGKDSSGTGTKRSTSKQAGKGDIHESPERYQRDNQTLLLQVEALQAQIEEQTQLSKEQLQALLEDRRIHMEEAQLQHQRDQDKIKTLTDKLNKTQNLLYESTRDFLQLKSDVRASEKAWMVEKENLLRKIGKDSDQLIGRETEREKKQRDTKKMLQAEREAGKPHSRDVKTLQEELMQEQRLSNMYREQCITLESELARISEERDVGRELFKARSEKMGKRLKLVTQRYEALEKRRNMEVEGFKNDLKQLRQKLKDVEKQLFKVTLNIGPDQDLAILNEVRQGNRLTRKIQEELKYLKAKIYGLENELRVC", "length": 504, "header": "tr|A0A8V0YGZ6-1|A0A8V0YGZ6_CHICK Isoform 1 of Coiled-coil domain containing 77 OS=Gallus gallus OX=9031 GN=CCDC77 PE=4 SV=1 CANONICAL=A0A8V0YGZ6-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YDN0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGZ6/entry#A0A8V0YDN0-1", "sequence": { "sequence": "MSATGGSAGRSSRSRRLATPHSSSRHSSSQPQSQGDSTPLPSINERLAFLRPSRELLEYYRKKIADFDEEHEDLVKRLERYKETYDEQHKLQWEVRQREEEIAELQKALSDMQVYLFQEREHVLRLYSENDRLKIRELEDRKKIQHLLALVGTDAGEVTYFHKEPPHKVTVLQRPARSRDSHDGKDSSGTGTKRSTSKQAGKGDIHESPERYQRDNQTLLLQVEALQAQIEEQTQLSKEQLQALLEDRRIHMEEAQLQHQRDQDKIKTLTDKLNKTQNLLYESTRDFLQLKSDVRASEKAWMVEKENLLRKIGKDSDQLIGRETEREKKQRDTKKMLQAEREAGKPHSRDVKTLQEELMQEQRLSNMYREQCITLESELARISEERDVGRELFKARSEKMGKRLKLVTQRYEALEKRRNMEVEGFKNDLKQLRQKLKDVEKQLFKVTLNIGPDQDLAILNEVRQGNRLTRKIQEELKYLKAKIYGLENELRVC", "length": 493, "header": "tr|A0A8V0YDN0-1|A0A8V0YGZ6_CHICK Computationally mapped isoform of Coiled-coil domain containing 77 OS=Gallus gallus OX=9031 GN=CCDC77 PE=4 SV=1 CANONICAL=A0A8V0YGZ6-1" }, "locus": { "chromosome": "1", "start_pos": 60348865, "end_pos": 60337193, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029339.1", "url": "https://www.ensembl.org/id/ENSGALT00010029339.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017037.1", "url": "https://www.ensembl.org/id/ENSGALP00010017037.1" } ] } }, { "isoform_ac": "A0A8V0YGZ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGZ6/entry#A0A8V0YGZ6-1", "sequence": { "sequence": "MSATGGSAGRSSRSRRSRHYKVFVRSMLATPHSSSRHSSSQPQSQGDSTPLPSINERLAFLRPSRELLEYYRKKIADFDEEHEDLVKRLERYKETYDEQHKLQWEVRQREEEIAELQKALSDMQVYLFQEREHVLRLYSENDRLKIRELEDRKKIQHLLALVGTDAGEVTYFHKEPPHKVTVLQRPARSRDSHDGKDSSGTGTKRSTSKQAGKGDIHESPERYQRDNQTLLLQVEALQAQIEEQTQLSKEQLQALLEDRRIHMEEAQLQHQRDQDKIKTLTDKLNKTQNLLYESTRDFLQLKSDVRASEKAWMVEKENLLRKIGKDSDQLIGRETEREKKQRDTKKMLQAEREAGKPHSRDVKTLQEELMQEQRLSNMYREQCITLESELARISEERDVGRELFKARSEKMGKRLKLVTQRYEALEKRRNMEVEGFKNDLKQLRQKLKDVEKQLFKVTLNIGPDQDLAILNEVRQGNRLTRKIQEELKYLKAKIYGLENELRVC", "length": 504, "header": "tr|A0A8V0YGZ6-1|A0A8V0YGZ6_CHICK Isoform 1 of Coiled-coil domain containing 77 OS=Gallus gallus OX=9031 GN=CCDC77 PE=4 SV=1 CANONICAL=A0A8V0YGZ6-1" }, "locus": { "chromosome": "1", "start_pos": 60348865, "end_pos": 60337193, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029344.1", "url": "https://www.ensembl.org/id/ENSGALT00010029344.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017041.1", "url": "https://www.ensembl.org/id/ENSGALP00010017041.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:418149", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418149", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8M6YYE2-1", "protein_name": "Coiled-coil domain-containing protein 77 isoform X1", "gene_name": "ccdc77", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDSPPTKDHKSPSPDSPLPSISERLAYLRPSRELLDFYRQKVSQFDGEHEELLQKLEEHRSSTEEQHKLQWEIRQREEEIAELQNALSDMQIYLFQEREQALRLYAENDRLKIRELEDRKKIQHLLALVGPDPGEITYFHREPPHKVTIPQKKIQPRSHEELKMVKPRPVSAKGNKKSSKHGENSTDAEQQKRDNQTLLLQVEALQAQMEEQARLAKEQVEALMEERRIHLEERQIQQQRDSDRITALTDKLQCTQSLLMESTRDFLQLKFESRAQEKSWMMEKERLLRRLDCSEEREERAPSAELQIIQQSPADSGATHRQHIRALQEELKQAHKLADMYRDQCVSLETELSQIREEGDVGREIFKERSDKMAKRLQLMTRRYEALEKRRVMEVEGFKTDIRLLRQKVKDVEKILFKLTLGGSPKQDLAILREVRQTNRRTEKVQDQLKNLKTKICKLENELQFC", "length": 466 }, "evidence": [ { "id": "A0A8V0YGZ6", "url": "https://omabrowser.org/oma/group/A0A8V0YGZ6/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "D3ZHU5-1", "protein_name": "Coiled-coil domain containing 77", "gene_name": "Ccdc77", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MNFTPTHTPICRKITVASRRGAGSGFDDTNRWKKMADSVESTPLPSIEDRLAVLRPSQELLEYYQKKMANFEAENEDVLKKLELYRETCEEQHNLEWSLQQREGEIAELQRALSDMQVCLFQEREHVLRLYSENDRLRIRELEDKKKIQNLLALVGTDTGEVTYFLKEPPHKASILQKTIQAVDVCEPSASKADPTVSKRRIRVKDKEDISERYQRDIQTLLLQVEALQAQLGEQTKLSREQVEGLMEDRRIRIEEIQVQHQRNQEKIKELTKSLHHTQELLYQSTKDFLQLKFENQNKEKLWMLERDHLMSVMKQHRAQYRKKEDKLGKVVPTLHENHHAQNEYVKSLKDKLTQEKKLSNMYQEQCISLEEELARIREEEGVRREIFKDRSNKMGKRLQIMTRRYQALEHRRILEVEGFKTDIKALRQKLRDLEQTLYKATMNTHGNQDLAILCEVRDSNRRAHKIQGELKSLKSKMFSLENELRLC", "length": 488 }, "evidence": [ { "id": "A0A8V0YGZ6", "url": "https://omabrowser.org/oma/group/A0A8V0YGZ6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1SK78-1", "protein_name": "Coiled-coil domain containing 77", "gene_name": "CCDC77", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MNFTPTQSPVYRKLTTVSKHEAASGISSPTRWKGVSFSDSVQSTPLPSVKDRLAVLCPSQELLEYYQKKMSECEAENQGLLQKLELYKEACEGQHKLEWDLQQREKEIAELQKALSDMQVCLFQEREHVLRLYSENDRLRIRELEDKKKIQNLLALVGTDSGEVTYFYKEPPNKVSILQKNIQTIEMCEQNESSALRADSKGSRRKPAMKEKEERAEQQQRDVQTLILQVEALQAQLEEQTRLSREQVSGLMEERRIHMDEVQVHHQRYRDRITELTKSLHHTQELLYESTKDFLQLKFENQNKETSWMLEKDHLMSKIKQYRVQCKKREDKLGKVWPIHENHHNQNEYIKSLKDKIVQEKRLSNMYQEQCISLEEELARIREEEGVRREIFKDRTNKMGKRLQVMTKRYEALENRRALEVEGFKTDIKVLRQKLRDLEQMLYKATLNARANQDLAILYEVRDSNRRAHKIQGELKNLKSKVFGLENELRLC", "length": 492 }, "evidence": [ { "id": "A0A8V0YGZ6", "url": "https://omabrowser.org/oma/group/A0A8V0YGZ6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3H881-1", "protein_name": "Coiled-coil domain-containing protein 77 isoform X1", "gene_name": "Ccdc77", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MNFTPTHTPVCRKITTASKRGSACGFSDPNRWKKMADSVESTPLPSTEDRLAVLCPSQELLEYYQKKMADCETENEDLLKKLDLYRESCEGQHKLEWNLQQREEEIAELQKALSDMQVCLFQEREHVLRLYSENDRLRIRELEDKKKIQNLLALVGTDTGEVTYFCKEPPHKVSILQKTIQAVEACEQYEPSAFKADPKESKRRATIKEKEDMCDRYQRNIHTLMLQVEALQAQLGEQTKLSREQIEGLMEDRRIRIEEIQVQHQRNQDKVKELTKSLHYTQELLYESTKDFLQLRFENQNKEKVWMLEKDHLMSKIKQYKVQCKKKEDKLGKVIPALPENHHTQNEYIKSLKDKLMQEKKLSSMYQQQCISLEEELARIREEEGVRREIFKDRSNKMGKRLQTMTKRYEALEHRRMLEVEGFKTDIKVLRQKLRDLEQMLYKATVNTRENQDLAILCEVRDSNRRAHKIQGELKALKSKVFGLENDLRLC", "length": 491 }, "evidence": [ { "id": "A0A8V0YGZ6", "url": "https://omabrowser.org/oma/group/A0A8V0YGZ6/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q9BR77-1", "protein_name": "Coiled-coil domain-containing protein 77", "gene_name": "CCDC77", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNFTPTHTPVCRKRTVVSKRGVAVSGPTKRRGMADSLESTPLPSPEDRLAKLHPSKELLEYYQKKMAECEAENEDLLKKLELYKEACEGQHKLECDLQQREEEIAELQKALSDMQVCLFQEREHVLRLYSENDRLRIRELEDKKKIQNLLALVGTDAGEVTYFCKEPPHKVTILQKTIQAVGECEQSESSAFKADPKISKRRPSRERKESSEHYQRDIQTLILQVEALQAQLGEQTKLSREQIEGLIEDRRIHLEEIQVQHQRNQNKIKELTKNLHHTQELLYESTKDFLQLRSENQNKEKSWMLEKDNLMSKIKQYRVQCKKKEDKIGKVLPVMHESHHAQSEYIKSLKDKLVQEKKLSNMYQEQCISLEEELARIREEEGMRREIFKDRTNKMGKRLQIMTKRYEALERRRILEVEGFKTDIKVLRQKLKDLEQMLYKATVNARANQDLALLCEVRDSNRRAHKIQGELKNLKSKVFGLENELRLC", "length": 488 }, "evidence": [ { "id": "A0A8V0YGZ6", "url": "https://omabrowser.org/oma/group/A0A8V0YGZ6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9CZH8-1", "protein_name": "Coiled-coil domain-containing protein 77", "gene_name": "Ccdc77", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNFTPTRTPICRKISFASKRGAGSGFGDTNRWKKMADSMESTPLPSVEDRLAVLCPSQELLEYYQKKMANCESENEDLLKKLELYREACEEQHKLEWNLQQREEEIAELQKALSDMQVCLFQEREHVLRLYSENDRLRIRELEDKKKIQNLLALVGPDAGEVTYFHKEPPHRVSILQKTLQAAVACEPSASKADPGVSKRQVRIKDKEGISERHQRDTEMLLLQVEALQAQLGEQTKLSREQVEGLMEDRRIRVEEIQVQHQRNQEKIMELTKSLHHTQELLYESTKDFLQLKFENQNKEKVWMLEKDHLMSKITQYRAQCKKKEDKLGKVVPILHESHHTQNEYIKSLKDKLIQEKKLSNMYQEQCISLEEELARIREEEGVRREIFKDRSNKMGKRLQIMTKRYQALEHRRALEVEGFKTDIKSLRQKLRDLEQMLYKATMNNTHGDQDLAMLCEVRDSNRRAHKIQGELKNLKSKVFGLENALRLC", "length": 489 }, "evidence": [ { "id": "A0A8V0YGZ6", "url": "https://omabrowser.org/oma/group/A0A8V0YGZ6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGZ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGZ6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 227, "end_pos": 229, "annotation": "n_glycosylation_sequon" }, { "start_pos": 285, "end_pos": 287, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 227, "end_pos": 229 }, { "start_pos": 285, "end_pos": 287 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YID6-1", "uniprot_ac": "A0A8V0YID6", "uniprot_id": "A0A8V0YID6_CHICK", "mass": { "chemical_mass": 103459.0, "monoisotopic_mass": 103459.0 }, "refseq": { "ac": "XP_015140219", "name": "SCY1-like protein 2 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015140219" }, "gene_names": [ { "name": "SCYL2", "type": "recommended", "evidence": [ { "id": "A0A8V0YID6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YID6" } ] }, { "name": "SCYL2", "type": "synonym", "evidence": [ { "id": "XP_015140219", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015140219" } ] } ], "protein_names": [ { "name": "SCY1-like protein 2", "type": "recommended", "evidence": [ { "id": "A0A8V0YID6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YID6/entry#names_and_taxonomy" } ] }, { "name": "Coated vesicle-associated kinase of 104 kDa", "type": "synonym", "evidence": [ { "id": "A0A8V0YID6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YID6/entry#names_and_taxonomy" } ] }, { "name": "SCY1-like protein 2 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015140219", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015140219" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015140219", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015140219" } ] }, { "annotation": "Component of the AP2-containing clathrin coat that may regulate clathrin-dependent trafficking at plasma membrane, TGN and endosomal system. A possible serine/threonine-protein kinase toward the beta2-subunit of the plasma membrane adapter complex AP2 and other proteins in presence of poly-L-lysine has not been confirmed. By regulating the expression of excitatory receptors at synapses, plays an essential role in neuronal function and signaling and in brain development.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YDP7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDP7#function" }, { "database": "UniProtKB", "id": "ARBA00059574", "url": "https://www.uniprot.org/uniprotkb/ARBA00059574#function" }, { "database": "UniProtKB", "id": "A0A8V0YID6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YID6#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YID6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YID6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SCYL2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YID6", "locus": { "chromosome": "1", "start_pos": 47330760, "end_pos": 47298539, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010011529", "url": "https://www.ensembl.org/id/ENSGALG00010011529" } ] } } ], "crossref": [ { "id": "A0A8V0YID6", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YID6", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd14011", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14011", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "417930", "url": "https://www.ncbi.nlm.nih.gov/gene/417930", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000719", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000719", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011009", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011009", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051177", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051177", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "MAHKCIP", "url": "https://omabrowser.org/oma/group/MAHKCIP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y9Z2", "url": "https://www.orthodb.org/?gene=A0A8V0Y9Z2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YDP3", "url": "https://www.orthodb.org/?gene=A0A8V0YDP3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YDP7", "url": "https://www.orthodb.org/?gene=A0A8V0YDP7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YID6", "url": "https://www.orthodb.org/?gene=A0A8V0YID6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12984", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12984", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12984:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12984:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00069", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00069", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015140219", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015140219", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Y9Z2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9Z2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y9Z2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9Z2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YDP3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDP3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YDP3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDP3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YDP7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDP7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YDP7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDP7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YID6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YID6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YID6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YID6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MESMLNKLKSTVTKVTADVTSAVMGNPVTREFDVGRHIASGGNGLAWKIFNGTKKSTKQEVAVFVFDKKLIDKYQKFEKDQIIDSLKRGVQQLTRLRHPRLLTVQHPLEESRDCLAFCTEPVCASLANVLGSWDNLPSPVPSDIKEYKLYDVETKYGLLQVSEGLSFLHSSVKMVHGNITPENIILNKSGAWKITGFDFCIQSTNPSEQEPKFPCKEWDPNLPSLCLPNPEYLAPEYILSVSCETASDMYSLGAVMYAVFNKGKPIFEVNKQDIYKSFSRQLDQLSRLSSSTLQNIPEEVREHVKLLLNVAPAVRPDADQMTKIPFFDDVGAMTLQYFDSLFQRDNLQKSQFFKGLPKVLPKLPKRVIIQRILPCLTSEFVNPDMVPFVLPNVLLIAEECTKEEYIRLILPDLGPVFKQQEPIQASNMILLIFLQKMDLLLTKTPPDEIKNSVLPMVYRALEAPSIQIQELCLNIIPTFANLIDYPSMKNSLIPRIKTACLQTSSLAVRVNSLVCLGKILEYLDKWFVLDDILPFLQQIPSKEPAVLMGILGIYKCTFTHKKLGITKEQLAGRVLPHLIPLSIENNLNLNQFNSFICVIKDMLNRLEAEHKTKLEQLHVMQEQQKSLDIANQMSVSEEARSSSTNNQIDKVFNNTGTDLLTSGPDSRENELSSVQKKASLTLEEKQKLAKEQEQAQKLKSQQPLKPLATSVTPPVKQTKDLTDTLIDNMSSLTSHSINKAKVASSNSFSSVSSMGVGMGFSSPVDSTKRNMTNGLNTNMGFQTAGFSMGSGPTAQNFFSGPSATGTTKMSIVPTASMPNYSPMSAASAISPLTQPNRPPDMSALDNLFGPQKPKVSMKQLAQQKSNQWVNQFVPPQGSPSVSSSVMGPQMNMIGQTGFGIQGNPFFAPQNFAQPANTMTNSSSASNDLKDLFG", "length": 933, "header": "tr|A0A8V0YID6-1|A0A8V0YID6_CHICK Isoform 1 of SCY1-like protein 2 OS=Gallus gallus OX=9031 GN=SCYL2 PE=1 SV=1 CANONICAL=A0A8V0YID6-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Y9Z2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YID6/entry#A0A8V0Y9Z2-1", "sequence": { "sequence": "MSPVQSWEIPLPGNLMWVDILPVVVTVLPGRYLMELKNRQSRDCLAFCTEPVCASLANVLGSWDNLPSPVPSDIKEYKLYDVETKYGLLQVSEGLSFLHSSVKMVHGNITPENIILNKSGAWKITGFDFCIQSTNPSEQEPKFPCKEWDPNLPSLCLPNPEYLAPEYILSVSCETASDMYSLGAVMYAVFNKGKPIFEVNKQDIYKSFSRQLDQLSRLSSSTLQNIPEEVREHVKLLLNVAPAVRPDADQMTKIPFFDDVGAMTLQYFDSLFQRDNLQKSQFFKGLPKVLPKLPKRVIIQRILPCLTSEFVNPDMVPFVLPNVLLIAEECTKEEYIRLILPDLGPVFKQQEPIQILLIFLQKMDLLLTKTPPDEIKNSVLPMVYRALEAPSIQIQELCLNIIPTFANLIDYPSMKNSLIPRIKTACLQTSSLAVRVNSLVCLGKILEYLDKWFVLDDILPFLQQIPSKEPAVLMGILGIYKCTFTHKKLGITKEQLAGRVLPHLIPLSIENNLNLNQFNSFICVIKDMLNRLEAEHKTKLEQLHVMQEQQKSLDIANQMSVSEEARSSSTNNQIDKVFNNTGTDLLTSGPDSRENELSSVQKKASLTLEEKQKLAKEQEQAQKLKSQQPLKPLATSVTPPVKQTKDLTDTLIDNMSSLTSHSINKAKVASSNSFSSVSSMGVGMGFSSPVDSTKRNMTNGLNTNMGFQTAGFSMGSGPTAQNFFSGPSATGTTKMSIVPTASMPNYSPMSAASAISPLTQPNRPPDMSALDNLFGPQKPKVSMKQLAQQKSNQWVNQFVPPQGSPSVSSSVMGPQMNMIGQTGFGIQGNPFFAPQNFAQPANTMTNSSSASNDLKDLFG", "length": 859, "header": "tr|A0A8V0Y9Z2-1|A0A8V0Y9Z2_CHICK Computationally mapped isoform of SCY1 like pseudokinase 2 OS=Gallus gallus OX=9031 GN=SCYL2 PE=1 SV=1 CANONICAL=A0A8V0YID6-1" }, "locus": { "chromosome": "1", "start_pos": 47328246, "end_pos": 47303099, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027588.1", "url": "https://www.ensembl.org/id/ENSGALT00010027588.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015800.1", "url": "https://www.ensembl.org/id/ENSGALP00010015800.1" } ] } }, { "isoform_ac": "A0A8V0YDP3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YID6/entry#A0A8V0YDP3-1", "sequence": { "sequence": "MVRRWQSNYSSVRDCLAFCTEPVCASLANVLGSWDNLPSPVPSDIKEYKLYDVETKYGLLQVSEGLSFLHSSVKMVHGNITPENIILNKSGAWKITGFDFCIQSTNPSEQEPKFPCKEWDPNLPSLCLPNPEYLAPEYILSVSCETASDMYSLGAVMYAVFNKGKPIFEVNKQDIYKSFSRQLDQLSRLSSSTLQNIPEEVREHVKLLLNVAPAVRPDADQMTKIPFFDDVGAMTLQYFDSLFQRDNLQKSQFFKGLPKVLPKLPKRVIIQRILPCLTSEFVNPDMVPFVLPNVLLIAEECTKEEYIRLILPDLGPVFKQQEPIQILLIFLQKMDLLLTKTPPDEIKNSVLPMVYRALEAPSIQIQELCLNIIPTFANLIDYPSMKNSLIPRIKTACLQTSSLAVRVNSLVCLGKILEYLDKWFVLDDILPFLQQIPSKEPAVLMGILGIYKCTFTHKKLGITKEQLAGRVLPHLIPLSIENNLNLNQFNSFICVIKDMLNRLEAEHKTKLEQLHVMQEQQKSLDIANQMSVSEEARSSSTNNQIDKVFNNTGTDLLTSGPDSRENELSSVQKKASLTLEEKQKLAKEQEQAQKLKSQQPLKPLATSVTPPVKQTKDLTDTLIDNMSSLTSHSINKAKVASSNSFSSVSSMGVGMGFSSPVDSTKRNMTNGLNTNMGFQTAGFSMGSGPTAQNFFSGPSATGTTKMSIVPTASMPNYSPMSAASAISPLTQPNRPPDMSALDNLFGPQKPKVSMKQLAQQKSNQWVNQFVPPQGSPSVSSSVMGPQMNMIGQTGFGIQGNPFFAPQNFAQPANTMTNSSSASNDLKDLFG", "length": 830, "header": "tr|A0A8V0YDP3-1|A0A8V0YID6_CHICK Computationally mapped isoform of SCY1-like protein 2 OS=Gallus gallus OX=9031 GN=SCYL2 PE=1 SV=1 CANONICAL=A0A8V0YID6-1" }, "locus": { "chromosome": "1", "start_pos": 47328246, "end_pos": 47310572, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027587.1", "url": "https://www.ensembl.org/id/ENSGALT00010027587.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015799.1", "url": "https://www.ensembl.org/id/ENSGALP00010015799.1" } ] } }, { "isoform_ac": "A0A8V0YDP7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YID6/entry#A0A8V0YDP7-1", "sequence": { "sequence": "MKQNTNSKVVHWCTVDTMESMLNKLKSTVTKVTADVTSAVMGNPVTREFDVGRHIASGGNGLAWKIFNGTKKSTKQEVAVFVFDKKLIDKYQKFEKDQIIDSLKRGVQQLTRLRHPRLLTVQHPLEESRDCLAFCTEPVCASLANVLGSWDNLPSPVPSDIKEYKLYDVETKYGLLQVSEGLSFLHSSVKMVHGNITPENIILNKSGAWKITGFDFCIQSTNPSEQEPKFPCKEWDPNLPSLCLPNPEYLAPEYILSVSCETASDMYSLGAVMYAVFNKGKPIFEVNKQDIYKSFSRQLDQLSRLSSSTLQNIPEEVREHVKLLLNVAPAVRPDADQMTKIPFFDDVGAMTLQYFDSLFQRDNLQKSQFFKGLPKVLPKLPKRVIIQRILPCLTSEFVNPDMVPFVLPNVLLIAEECTKEEYIRLILPDLGPVFKQQEPIQILLIFLQKMDLLLTKTPPDEIKNSVLPMVYRALEAPSIQIQELCLNIIPTFANLIDYPSMKNSLIPRIKTACLQTSSLAVRVNSLVCLGKILEYLDKWFVLDDILPFLQQIPSKEPAVLMGILGIYKCTFTHKKLGITKEQLAGRVLPHLIPLSIENNLNLNQFNSFICVIKDMLNRLEAEHKTKLEQLHVMQEQQKSLDIANQMSVSEEARSSSTNNQIDKVFNNTGTDLLTSGPDSRENELSSVQKKASLTLEEKQKLAKEQEQAQKLKSQQPLKPLATSVTPPVKQTKDLTDTLIDNMSSLTSHSINKAKVASSNSFSSVSSMGVGMGFSSPVDSTKRNMTNGLNTNMGFQTAGFSMGSGPTAQNFFSGPSATGTTKMSIVPTASMPNYSPMSAASAISPLTQPNRPPDMSALDNLFGPQKPKVSMKQLAQQKSNQWVNQFVPPQGSPSVSSSVMGPQMNMIGQTGFGIQGNPFFAPQNFAQPANTMTNSSSASNDLKDLFG", "length": 946, "header": "tr|A0A8V0YDP7-1|A0A8V0YID6_CHICK Computationally mapped isoform of SCY1-like protein 2 OS=Gallus gallus OX=9031 GN=SCYL2 PE=1 SV=1 CANONICAL=A0A8V0YID6-1" }, "locus": { "chromosome": "1", "start_pos": 47328246, "end_pos": 47300397, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027593.1", "url": "https://www.ensembl.org/id/ENSGALT00010027593.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015804.1", "url": "https://www.ensembl.org/id/ENSGALP00010015804.1" } ] } }, { "isoform_ac": "A0A8V0YID6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YID6/entry#A0A8V0YID6-1", "sequence": { "sequence": "MESMLNKLKSTVTKVTADVTSAVMGNPVTREFDVGRHIASGGNGLAWKIFNGTKKSTKQEVAVFVFDKKLIDKYQKFEKDQIIDSLKRGVQQLTRLRHPRLLTVQHPLEESRDCLAFCTEPVCASLANVLGSWDNLPSPVPSDIKEYKLYDVETKYGLLQVSEGLSFLHSSVKMVHGNITPENIILNKSGAWKITGFDFCIQSTNPSEQEPKFPCKEWDPNLPSLCLPNPEYLAPEYILSVSCETASDMYSLGAVMYAVFNKGKPIFEVNKQDIYKSFSRQLDQLSRLSSSTLQNIPEEVREHVKLLLNVAPAVRPDADQMTKIPFFDDVGAMTLQYFDSLFQRDNLQKSQFFKGLPKVLPKLPKRVIIQRILPCLTSEFVNPDMVPFVLPNVLLIAEECTKEEYIRLILPDLGPVFKQQEPIQASNMILLIFLQKMDLLLTKTPPDEIKNSVLPMVYRALEAPSIQIQELCLNIIPTFANLIDYPSMKNSLIPRIKTACLQTSSLAVRVNSLVCLGKILEYLDKWFVLDDILPFLQQIPSKEPAVLMGILGIYKCTFTHKKLGITKEQLAGRVLPHLIPLSIENNLNLNQFNSFICVIKDMLNRLEAEHKTKLEQLHVMQEQQKSLDIANQMSVSEEARSSSTNNQIDKVFNNTGTDLLTSGPDSRENELSSVQKKASLTLEEKQKLAKEQEQAQKLKSQQPLKPLATSVTPPVKQTKDLTDTLIDNMSSLTSHSINKAKVASSNSFSSVSSMGVGMGFSSPVDSTKRNMTNGLNTNMGFQTAGFSMGSGPTAQNFFSGPSATGTTKMSIVPTASMPNYSPMSAASAISPLTQPNRPPDMSALDNLFGPQKPKVSMKQLAQQKSNQWVNQFVPPQGSPSVSSSVMGPQMNMIGQTGFGIQGNPFFAPQNFAQPANTMTNSSSASNDLKDLFG", "length": 933, "header": "tr|A0A8V0YID6-1|A0A8V0YID6_CHICK Isoform 1 of SCY1-like protein 2 OS=Gallus gallus OX=9031 GN=SCYL2 PE=1 SV=1 CANONICAL=A0A8V0YID6-1" }, "locus": { "chromosome": "1", "start_pos": 47328246, "end_pos": 47303047, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027590.1", "url": "https://www.ensembl.org/id/ENSGALT00010027590.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015802.1", "url": "https://www.ensembl.org/id/ENSGALP00010015802.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 793, "start_aa": "Thr", "end_pos": 793, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr793", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 814, "start_aa": "Thr", "end_pos": 814, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr814", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "D4A1Y0-1", "protein_name": "SCY1-like protein 2", "gene_name": "Scyl2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MESMLNKLKSTVTKVTADVTSAVMGNPVTREFDVGRHIASGGNGLAWKIFNGTKKSTKQEVAVFVFDKKLIDKYQKFEKDQIIDSLKRGVQQLTRLRHPRLLTVQHPLEESRDCLAFCTEPVFASLANVLGNWENLPSSISPDIKDYKLYDVETKYGLLQVSEGLSFLHSSVKMVHGNVTPENIILNKSGAWKIMGFDFCVSSSNPSEQEPKFPCKEWDPNLPSLCLPNPEYLAPEYILSVSCETASDMYSLGAVMYAVFNKGRPIFEVNKQDIYKSFSRQLDQLSRLGSSSLTSIPEEVREHVKLLLNVTPTVRPDADQMTKIPFFDDVGAVTLQYFDTLFQRDNLQKSQFFKGLPKVLPKLPKRVIVQRILPCLTSEFVNPDMVPFVLPNVLLIAEECTKEEYIKLILPELGPVFKQQEPIQILLIFLQKMDLLLTKTPPDEIKNSVLPMVYRALEAPSIQIQELCLNIIPTFANLIDYPSMKNALIPRIKNACLQTSSLAVRVNSLVCLGKILEYLDKWFVLDDILPFLQQIPSKEPAVLMGILGIYKCTFTHKKLGITKEQLAGKVLPHLIPLSIENNLNLNQFSSFIAVIKEMLSRLESEHRTKLEQLHIMQEQQRSLDIGNQMSTSEETKVTPSGTQQIDKVFNNIGADLLSGGESENREDGLQGKQKRGSLTLEEKQKLAKEQEQAQKLKSQQPLKPQVHTPIAPVKQTKDLTDTLMENMSSLTSLSVSTPKISASSTFTSVPSTGLSMMFSTPIDNTKRNLTNGLNANMGFQTSGFNMPVNPNQNFFSGTSTAGVTTMTLGAPPTMSNFSPLSIPPASVKQTQQRPPDMSALNNLFGPQKPKVSMNQLSQQKPNQWLNQFVPPQGSPGMGSAAMGTQVNVMGQAAFGMQGNPFFNPQSFAQPPPTTMTSSSSASNDLKDLFG", "length": 930 }, "evidence": [ { "id": "A0A8V0YID6", "url": "https://omabrowser.org/oma/group/A0A8V0YID6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F4I313-1", "protein_name": "SCY1-like protein 2 A", "gene_name": "SCYL2A", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSINMRTLTQALAKTAAVIEKTVQTTVQEVTGPKPLQDYELLDQIGSGGPGLAWKLYSAKARDSTRPQQYPTVCVWVLDKRALSEARARAGLSKAAEDAFLDLIRADSGKLVRLRHPGVVHVVQALDENKNAMAMVTEPLFASVANALGNVENVDNVPKDLKSMEMSLLEVKHGLLQIAETLNFLHNNAHLIHRAVSPENVFITSAGSWKLAGFGFAISQAQDGNLDNLQSFHYSEYDVEDSILPLQPSLNYTAPELVRSKTSSAGVSSDIFSFGCLTYHLVARKPLFDCHNNVKMYMNTLNYLTNETFSSIPSDLVSDLQRMLSMNESYRPTALDFTGSSFFRSDTRLRALRFLDHMLERDNMQKSEFLKALSDMWKDFDSRVLRYKVLPPLCAELRNLVMQPVILPMVLTIAESQDKNDFELTTLPALVPVLSTATGDTLLLLIKRAELIINKTNAEHLVSHVLPLLLRAYNDNDVRIQEEVLKRSTSVAKQLDGQVVRQAILPRVHGLALKTTVAAVRVNALLCLAELVQTLDKLAVTEILQTIQRCTAVDRSAPTLMCTLAIANAILKQYGVEFTSEHVLPLIIPLLTAQQLNVQQFAKYILFVKDILRKIEEKRGVTVNDSGVPEVKPGCVADGLQFQTPTKKTEKVASAAKNSPAWDEDWALPTKISAPRDPGPANSPQFNNSTVQSQSSNRTSVPTTCPAVDLEWPPRQSFNATAQPANDETRINAAGTPTTPSFDELDPFANWPPRPNSASTASGGFHNSTTTQPPINNSGSGLRNNLTDGRQFQTTNNDFWAFGNASLSSMKSQQETSGIRASNADPLTSFGIQNQNQGMPSFGSSSYGNQKPQADISSIFSSSRTEQSAMKLAPPPSIAVGRGRGRGRSGTSISKPNGSKQQQTEQPSLLDLL", "length": 913 }, "evidence": [ { "id": "A0A8V0YID6", "url": "https://omabrowser.org/oma/group/A0A8V0YID6/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "P53009-1", "protein_name": "Protein kinase-like protein SCY1", "gene_name": "SCY1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MMFWSSKTGITSKYSFSSSPTFTAEPWSIYTGRPKSSSSSSPSKVSIFMFDKKQFENYLLHYGIIKSKSGSRDKVLIQEAYEILRNQANNLAKLKHPNILTLIEPLEEHSKNFMFVTEFVTSSLETVFRETDDEEQNFLQGHVKDNIVVQRGILQLVNALDFVHNRASFVHLNIQPRAIFINENSDWKISGLGYLVKIPPGTNTSEYFLPQYDPRVPPFMHLQLNYTAPEIVFENTLTFKNDYFSLGLLIYFLYTGKDLFRSENSTSEYKLEYNKFESKISTMSWDNIFSKVPQKLRHCIPKLINRDIYSRYDNITLILDSEFFQDPLVKTLNFLDDLPTKNNEEKYVFLEGLVNLLPEFPPALLQKKFLPILLELLSQFCAEKVVSDKCVGKSLDLIIKIGSTLSQLSFQEKVYPVLLSDANFPVLLKKATICLIDNLDTLKQKVKRSDFLENILKPLFNYVLHDSESDITVVCQEKLLSQIPLALEVLDFPTVKQFLLPLLSNLFTKTTSLTVKNTCVTCFQIMIEHKSIDSYTCSETVLPLFKSMKTRDPRILSKLLKLFETVPLIITDEIVLVDQVLPLMWNYSMASTLTKSQYSGYTKAINKMSSDIQKHHIAKLDDKVNDIGEDAFHKVIEPTIMKKEDPETVAAKNIEVAAMQPVKKKTGSSYGETLPQSKSILNSKPLNPKNALATRGFPTRILNSPPQTPSSRTGSKVMTKGGSNDASSTKVEEEFNEFQSFSSTGSIRQTSAPSDVWMNSTPSPTPTSASSTNLPPGFSISLQPNKRKDGSSDIPRSNVYGSLI", "length": 804 }, "evidence": [ { "id": "A0A8V0YID6", "url": "https://omabrowser.org/oma/group/A0A8V0YID6/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q1L881-1", "protein_name": "SCY1-like protein 2", "gene_name": "scyl2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MESMLNKLKSTVTKVTADVTSAVMGNPVTREFEVGKHIASGGPGMSWRIYNGTKKSTKQEVAVFVFDKKVIDRYQKFEKDQIIDSLKKGIQQLTRLRHPRLLTVQHPLEESRDCLAFCTEPVFASLANVLGQWDNLPSPVPTDIKDYKLYDVETKYGLLQVSEGLSFLHSGVKMVHGNLCSENIILNKSGAWKIMGFDFSISSSNPSDAEPKYVCKEWDPNLPPLCLPNPEYVAPEYILSVSCDSASDMYSLGVLIHAVFNEGKPVFKVNKQDIFKSFSRQLDQLSHLSPGVLSQIPEEVRQHVKMLLSVTSNVRPDADQMTKIPFFDDVGAMTLQYFDSLFQRDNLQKSQFFKGLPKVLPKLPKRVVVYRILPALMSEFVNPDMVPFILPNVLLIAEECTKEEYVRLVLPDLTPVFKMQEPVQILLIFLQKMDLLLTKTPPEDIKNSVLPMVYRAVEAPSVQIQELCLNIIPTFANLIEYPSMKNSLIPRIKSTCLQTSSLAVRVNSLVCLGKILEYLDKWFVIDEILPFLQQIPSREPAVLMGILGIYKCTFTHKKLGIPKEHLAGKSLPHLVSLSIDNNLNLNQFNSFMAVIKDMLTRMEAEHKVKLEQLHIMQEQQRSLNITNPINQSEDTKSTPSPATQVRDIDDIFGGSSANAGVNGKENGSSTVSQPSRVSLTLEEKQRLAKEQEQAAKLRSQQPLAPQSIKSATTTPQAKDLTSSLLNNMTSLNNMSLNSGTRTMPMQGNTISSTFPAAPTMGGMSTMSVSNGFNSPIGFQTGGMGMGMRAPTPALYGGMATTTSTPNFSALTQNHNQNQPGKPPDMSALDSLFASNKPKVSLNQMAPKPTPGTNAPSPWINQFGSGQPPQSAPIQSNPMGMSGVQGGFGMQANPFFNPQNFSQPAASSTMNTGMMKQSASVNNDLKDLFG", "length": 929 }, "evidence": [ { "id": "A0A8V0YID6", "url": "https://omabrowser.org/oma/group/A0A8V0YID6/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q55BQ3-1", "protein_name": "Probable inactive serine/threonine-protein kinase scy2", "gene_name": "scy2", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MDTTKSFNFKEKVRGFLGSAASVISPIKDHDLKEVVGQDKFWKIYQSTKKTTNTECSLFVFEKKLYEKVSKSNLENVITFLKKEATTLQRLRHPSILQVVSVMEETKTHIHFATEPILATLEDLLGYYRQRKKSTVDQSSQSEEGYKKKDFTFEELELKAGIFQILDGLLFLNQTAKLLHRNISPESIFITKDLKWKLGGLGFTCSIETKEPPISNLSLQDLREYQYISGGGGGESSNNSNYILPQLDYLAPEFISQRKFETNSDLFSIGRLIFELSINLEQKALDSHLISQLPKLGVISYYNTMIEQVRRQSTMNTQRSDSAKVCTILLGDPMLRGDLENFIRSSFFQDVLTKTLLYLANISQKEDESKLQFFRGLLRIVQQFSPRIQNNYILPVLLSEISNDRIIYVLLPNIMSISANHVKKETFQSKVLPAISNILQSKEPKPEVLSCVLENLPMLLQKCSLDQIKKILLPICLGSMCGPTNEIIFQCLSTAQPIAKFFDTDMISVAVIPRLTNLCVGGFPVHIRTKAIQWFTLLVPSIEKKIIVDSLLPNLEKILAGDNSPVILQSLVETYEALSKKLGGELLAKSVLPALIPLSSDKHIDLEQFKTVMKVIRDILNTYEQERINELSNLQRYTSPTPTKDENDTSFITVNNNNNNNNNISPTPINLTLPNSFGITPITTTATTQPSSSPSMLFPQPPQTSQPSSSPLSSSSSGTTSNPFNSVLSGNNKALIDSPDFGSTYISQPPSTQQLSSNISLTLPKSPPTTRPTVSNSSNSLFPTTNTTNNNNNNNNINNNNSSNNGSNYNSFNNSSFQNNSNQPVQPPPQQQQPLSFNSSFDFGSNLQPIKPTNTIAAQTPLPQPKLSYNSSFDIGNSNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNLNSFSNFGNNSSNGMNNSNNNFALNSGSTLPIKSTSTSKYDINLEDHVNSSSNSFSNNSFSNNNNSSSNNNTNNNNNNNGVGNFNSSNSFSSSSQSNYGFDQPLNPTTNSNHNSYGNNNYGNNSNNNNNNNTNSMNSSFKNMDLNQNNSYNNTLNDFNSFHNNVNSSFNMNPPSITKNVNFNSNNYNNNNNNNNNNNNNNYNNNNNSNFW", "length": 1125 }, "evidence": [ { "id": "A0A8V0YID6", "url": "https://omabrowser.org/oma/group/A0A8V0YID6/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q6P3W7-1", "protein_name": "SCY1-like protein 2", "gene_name": "SCYL2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MESMLNKLKSTVTKVTADVTSAVMGNPVTREFDVGRHIASGGNGLAWKIFNGTKKSTKQEVAVFVFDKKLIDKYQKFEKDQIIDSLKRGVQQLTRLRHPRLLTVQHPLEESRDCLAFCTEPVFASLANVLGNWENLPSPISPDIKDYKLYDVETKYGLLQVSEGLSFLHSSVKMVHGNITPENIILNKSGAWKIMGFDFCVSSTNPSEQEPKFPCKEWDPNLPSLCLPNPEYLAPEYILSVSCETASDMYSLGTVMYAVFNKGKPIFEVNKQDIYKSFSRQLDQLSRLGSSSLTNIPEEVREHVKLLLNVTPTVRPDADQMTKIPFFDDVGAVTLQYFDTLFQRDNLQKSQFFKGLPKVLPKLPKRVIVQRILPCLTSEFVNPDMVPFVLPNVLLIAEECTKEEYVKLILPELGPVFKQQEPIQILLIFLQKMDLLLTKTPPDEIKNSVLPMVYRALEAPSIQIQELCLNIIPTFANLIDYPSMKNALIPRIKNACLQTSSLAVRVNSLVCLGKILEYLDKWFVLDDILPFLQQIPSKEPAVLMGILGIYKCTFTHKKLGITKEQLAGKVLPHLIPLSIENNLNLNQFNSFISVIKEMLNRLESEHKTKLEQLHIMQEQQKSLDIGNQMNVSEEMKVTNIGNQQIDKVFNNIGADLLTGSESENKEDGLQNKHKRASLTLEEKQKLAKEQEQAQKLKSQQPLKPQVHTPVATVKQTKDLTDTLMDNMSSLTSLSVSTPKSSASSTFTSVPSMGIGMMFSTPTDNTKRNLTNGLNANMGFQTSGFNMPVNTNQNFYSSPSTVGVTKMTLGTPPTLPNFNALSVPPAGAKQTQQRPTDMSALNNLFGPQKPKVSMNQLSQQKPNQWLNQFVPPQGSPTMGSSVMGTQMNVIGQSAFGMQGNPFFNPQNFAQPPTTMTNSSSASNDLKDLFG", "length": 929 }, "evidence": [ { "id": "A0A8V0YID6", "url": "https://omabrowser.org/oma/group/A0A8V0YID6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8CFE4-1", "protein_name": "SCY1-like protein 2", "gene_name": "Scyl2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MESMLNKLKSTVTKVTADVTSAVMGNPVTREFDVGRHIASGGNGLAWKIFNGTKKSTKQEVAVFVFDKKLIDKYQKFEKDQIIDSLKRGVQQLTRLRHPRLLTVQHPLEESRDCLAFCTEPVFASLANVLGNWENLPSSISPDIKDYKLYDVETKYGLLQVSEGLSFLHSSVKMVHGNVTPENVILNKSGAWKIMGFDFCVSSSNPSEQEPKFPCKEWDPNLPSLCLPNPEYLAPEYILSVSCETASDMYSLGAVMYAVFNQGRPIFEVNKQDIYKSFSRQLDQLSRLGSSSLTSIPEEVREHVKLLLNVTPTVRPDADQMTKIPFFDDVGAVTLQYFDTLFQRDNLQKSQFFKGLPKVLPKLPKRVIVQRILPCLTSEFVNPDMVPFVLPNVLLIAEECTKEEYIKLILPELGPVFKQQEPIQILLIFLQKMDLLLTKTPPDEIKNSVLPMVYRALEAPSIQIQELCLNIIPTFANLIDYPSMKNALIPRIKNACLQTSSLAVRVNSLVCLGKILEYLDKWFVLDDILPFLQQIPSKEPAVLMGILGIYKCTFTHKKLGITKEQLAGKVLPHLIPLSIENNLNLNQFSSFIAVIKEMLSRLESEHRTKLEQLHVMQEQQRSLDIGNQMSTSEETKVAHSGSQQIDKVFNNIGADLLSGSESENREDGMQGKQKRGSLTLEEKQKLAKEQEQAQKLKSQQPLKPQVHTPIAPIKQTKDLTDTLMENMSSLTSLSVSTPKISASSTFTPVPSTGLGMMFSTPIDNTKRNLTNGLNANMGFQTSGFSMPVNPNQNFFSGTGTAGVTTMSLGAPPTMSNFSPLTIPPASVKQPQQRPTDMSALNNLFGPQKPKVSMNQLSQQKPNQWLNQFAPPQGSPVMGSAAMGTQGNVMGQAAFGMQGNPFFNPQNFAQPPPTTMTSSSSASNDLKDLFG", "length": 930 }, "evidence": [ { "id": "A0A8V0YID6", "url": "https://omabrowser.org/oma/group/A0A8V0YID6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VAR0-1", "protein_name": "Protein kinase domain-containing protein", "gene_name": "Dmel\\CG1951", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MDMINKFYSSAVQTVSTLSGVLPGNNVTREYEVLEQVCTAGVGLMWKVYNGHKKSTKQEVSVFVFEKKSLERWSKDDRETMLETLRRGVQQLTKIRHPHVLTVQHPLEESRDSLAFATEPVFASLANVVGDNVRSEKKLYDVEIRHGLLQLFDGLQFLHQDAKIVHRNISAETIVINKNRSWKLFGFDFCIANQPATDGTPHWPFREYTTSLHVLAQPSLEYTAPELALNSVNTPDSDLFSLGVLIFTIYAGKPLKMFGSDYSSFRRYANDLNQRKYPPMNAVPSELTESLKALLHPSANLRPKLHELKQIAYFQDVGVKTLSYLDSLYQWDNLQKSKFYKGLPQIIPTLPHRVNLHSILPYLVKEFVNSPMIPFVLPNVLLIAEMSSQREYCDHILPHLKPIFKLTDPIQILLIFMQKMDLLLKLTPAEEVKQSVLPLLYRSLECDMPQIQDLCLAVLPTFSTLIDYNAMKNSVLPRIKKLCLQSSNVSVKVNCLISIGKLLENLDKWLVLDEILPFLQQIQSREPAIIMGIIGIYKIAMTNTKLGITKDVMAHKCIPYLVPLSVENGLTIAQFNTIISLIKEMMGRVEQEQREKLQQLSTIQRDNKPKDASEILANELENSTLSPYGSINGNKINDDMFSGFTVGQPKAAIGAAIAPAKAREQLKISHNTISAPPAARPDILSSMMQSNLTGLGTITVAAAPPPTTTQMPSNNGWHSANPLVMNHQLASPQASNNNSFSLDDLDPFAGGRPSVGAPKANNTNGANMYTVQQPTVNYIYPTGYSLNSIQQHQQQQLLGKPSQAPTLQPQTQPLLPTDNQNLNALSQQDILNFLN", "length": 835 }, "evidence": [ { "id": "A0A8V0YID6", "url": "https://omabrowser.org/oma/group/A0A8V0YID6/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "protein kinase activity", "id": "GO:0004672", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004672", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YID6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YID6" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YID6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YID6" } ], "pmid": "" }, { "name": "signaling receptor binding", "id": "GO:0005102", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005102", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YID6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YID6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YID6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YID6" } ], "pmid": "" }, { "name": "endosome membrane", "id": "GO:0010008", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010008", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YID6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YID6" } ], "pmid": "" }, { "name": "clathrin-coated vesicle", "id": "GO:0030136", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030136", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YID6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YID6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "receptor internalization", "id": "GO:0031623", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031623", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YID6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YID6" } ], "pmid": "" }, { "name": "endosome to lysosome transport", "id": "GO:0008333", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008333", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YID6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YID6" } ], "pmid": "" }, { "name": "clathrin-dependent endocytosis", "id": "GO:0072583", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072583", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YID6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YID6" } ], "pmid": "" }, { "name": "pyramidal neuron development", "id": "GO:0021860", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021860", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YID6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YID6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 178, "end_pos": 180, "annotation": "n_glycosylation_sequon" }, { "start_pos": 187, "end_pos": 189, "annotation": "n_glycosylation_sequon" }, { "start_pos": 51, "end_pos": 53, "annotation": "n_glycosylation_sequon" }, { "start_pos": 653, "end_pos": 655, "annotation": "n_glycosylation_sequon" }, { "start_pos": 728, "end_pos": 730, "annotation": "n_glycosylation_sequon" }, { "start_pos": 770, "end_pos": 772, "annotation": "n_glycosylation_sequon" }, { "start_pos": 819, "end_pos": 821, "annotation": "n_glycosylation_sequon" }, { "start_pos": 920, "end_pos": 922, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YID6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YID6" }, { "id": "PS50011", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50011" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Protein kinase", "eco_id": "ECO_0000259", "start_pos": 32, "end_pos": 327, "start_aa": "Phe", "end_aa": "Phe", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 793, 814 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 178, "end_pos": 180 }, { "start_pos": 187, "end_pos": 189 }, { "start_pos": 51, "end_pos": 53 }, { "start_pos": 653, "end_pos": 655 }, { "start_pos": 728, "end_pos": 730 }, { "start_pos": 770, "end_pos": 772 }, { "start_pos": 819, "end_pos": 821 }, { "start_pos": 920, "end_pos": 922 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YFY6-1", "uniprot_ac": "A0A8V0YFY6", "uniprot_id": "A0A8V0YFY6_CHICK", "mass": { "chemical_mass": 44538.0, "monoisotopic_mass": 44538.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Protein FAM184A/B N-terminal domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A8V0YFY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFY6/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFY6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFY6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFY6", "locus": {} } ], "crossref": [ { "id": "A0A8V0YFY6", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YFY6", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR039478", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039478", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR18870", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR18870", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR18870:SF8", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR18870:SF8", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15665", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15665", "database": "Pfam", "categories": [ "Protein 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}, { "database": "Ensembl Peptide", "id": "ENSGALP00010016639.1", "url": "https://www.ensembl.org/id/ENSGALP00010016639.1" } ] } }, { "isoform_ac": "A0A8V0YFY6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFY6/entry#A0A8V0YFY6-1", "sequence": { "sequence": "MASSINKSRQPGTCNGSKAPRGSSAEGYNKEIHMQMCKKIAQLTKVIYALNTKNDEHEDSIQALREAHEEEVQHILAEMKETIVQYKSKVEEEQLLRKHIQALETAVEQHRRVKEEALAELTQCKKQVEEREPRAKVKLTQMALSKDTVDTNADFENKLPHLNEETNGLLNECKLSRRENLDEDILAEKISMEGQVLVNEMENLRSENQGAIKEYTQKTNQLRASCERGRESTQQSMTETKNHHQQREMEQRNCSEVEKGFWMQQVKKLEADLEEKSQKINEKKKHSQKLKERIQELQMQLDEFKRKSECEIKQLEKEKEALTGKLQNSSLETCSAELHLNADHKLGLKPASRFVPQLDYGLYIQDEDDLKRSNLRKVLDGQKD", "length": 384, "header": "tr|A0A8V0YFY6-1|A0A8V0YFY6_CHICK Isoform 1 of Protein FAM184A/B N-terminal domain-containing protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0YFY6-1" }, "locus": { "chromosome": "4", "start_pos": 75487114, "end_pos": 75460598, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028885.1", "url": "https://www.ensembl.org/id/ENSGALT00010028885.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016644.1", "url": "https://www.ensembl.org/id/ENSGALP00010016644.1" } ] } }, { "isoform_ac": "A0A8V0YKQ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFY6/entry#A0A8V0YKQ3-1", "sequence": { "sequence": "MKETIVQYKSKVEEEQLLRKHIQALETAVEQHRRVKEEALAELTQCKKQVEEREPRAKVKLTQMALSKDTVDTNADFENKLPHLNEETNGLLNECKLSRRENLDEDILAEKISMEGQVLVNEMENLRSENQGAIKEYTQKTNQLRASCERGRESTQQSMTETKNHHQQREMEQRNCSEVEKGFWMQQVKKLEADLEEKSQKINEKKKHSQKLKERIQELQMQLDEFKRKSECEIKQLEKEKEALTGKLQNSSLEDLFNSCKETILELQDT", "length": 270, "header": "tr|A0A8V0YKQ3-1|A0A8V0YKQ3_CHICK Computationally mapped isoform of Protein FAM184A/B N-terminal domain-containing protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0YFY6-1" }, "locus": { "chromosome": "4", "start_pos": 75483524, "end_pos": 75475297, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028878.1", "url": "https://www.ensembl.org/id/ENSGALT00010028878.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016637.1", "url": "https://www.ensembl.org/id/ENSGALP00010016637.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 15, "end_pos": 17, "annotation": "n_glycosylation_sequon" }, { "start_pos": 253, "end_pos": 255, "annotation": "n_glycosylation_sequon" }, { "start_pos": 328, "end_pos": 330, "annotation": "n_glycosylation_sequon" }, { "start_pos": 6, "end_pos": 8, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YFY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFY6" }, { "id": "PF15665", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15665" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Protein FAM184A/B N-terminal", "eco_id": "ECO_0000259", "start_pos": 46, "end_pos": 166, "start_aa": "Val", "end_aa": "Thr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 15, "end_pos": 17 }, { "start_pos": 253, "end_pos": 255 }, { "start_pos": 328, "end_pos": 330 }, { "start_pos": 6, "end_pos": 8 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { 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"n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YF19-1", "uniprot_ac": "A0A8V0YF19", "uniprot_id": "A0A8V0YF19_CHICK", "mass": { "chemical_mass": 77883.0, "monoisotopic_mass": 77883.0 }, "refseq": { "ac": "XP_015149172", "name": "actin-binding LIM protein 3 isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015149172" }, "gene_names": [ { "name": "ABLIM3", "type": "recommended", "evidence": [ { "id": "A0A8V0YF19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF19" } ] }, { "name": "ABLIM3", "type": "synonym", "evidence": [ { "id": "XP_015149172", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015149172" } ] } ], "protein_names": [ { "name": "Actin binding LIM protein family member 3", "type": "synonym", "evidence": [ { "id": "A0A8V0YF19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF19/entry#names_and_taxonomy" } ] }, { "name": "actin-binding LIM protein 3 isoform X3", "type": "synonym", "evidence": [ { "id": "XP_015149172", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015149172" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052544.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015149172", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015149172" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YF19", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF19" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ABLIM3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF19", "locus": { "chromosome": "13", "start_pos": 8162896, "end_pos": 8198082, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012297", "url": "https://www.ensembl.org/id/ENSGALG00010012297" } ] } } ], "crossref": [ { "id": "A0A8V0YF19", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YF19", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd09327", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09327", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd09328", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09328", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd09329", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09329", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd09330", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09330", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "416201", "url": "https://www.ncbi.nlm.nih.gov/gene/416201", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001781", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001781", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003128", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003128", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032402", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032402", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036886", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036886", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051618", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051618", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y8U4", "url": "https://www.orthodb.org/?gene=A0A8V0Y8U4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YDT9", "url": "https://www.orthodb.org/?gene=A0A8V0YDT9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YF19", "url": "https://www.orthodb.org/?gene=A0A8V0YF19", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YH52", "url": "https://www.orthodb.org/?gene=A0A8V0YH52", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YLX4", "url": "https://www.orthodb.org/?gene=A0A8V0YLX4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YLY0", "url": "https://www.orthodb.org/?gene=A0A8V0YLY0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YLY9", "url": "https://www.orthodb.org/?gene=A0A8V0YLY9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24213", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24213", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24213:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24213:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00412", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00412", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02209", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02209", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16182", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16182", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015149172", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015149172", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Y8U4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y8U4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y8U4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y8U4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YDT9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDT9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YDT9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDT9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YF19", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF19", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YF19-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF19-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YH52", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH52", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YH52-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH52-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLX4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLX4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLX4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLX4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLY0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLY0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLY0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLY0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLY9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLY9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLY9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLY9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSTSIPYQQNPYTAGSGSTVIQCYRCGDTCKGEVVRVQSNHFHIRCFTCQVCGCDLAQSGFFFKNQEYICTHDYQQLYGTRCDSCGDFITGEVISALGRTYHPKCFVCSTCRKPFPIGDKVTFSGKDCVCQNCSHSLISTKPIKIHGPSHCAGCKEEIKQGQSLLALEKQWHVSCFKCQTCGIILTGEYISKDGVPYCESDYHAQFGIKCETCDRYISGRVLEAGGKHYHPTCARCVRCHQMFTEGEEMYLTGSEVWHPICKQAARAEKKLKHRRTSETSISPPGSSIGSPNRVICAKVDNEILNYKDLAALPKIKAIYEVQRPDLISYEPYHRYTSDETLERYSYGESLGTLSPYSQDIYESFDIRQRRASSPGYIDSPTYSRQGMSPTIPRSPHHFYRSGTESGRSSPYYSQLDVRSSTPTSYQAPKHFHIPAAGESNIYRKPPIYKRHVAVDNISAATKSKTSEDIAQSSKYSPAYSPDPYYHSESEYWSFQGSPKAPRARRFSSGGEEDGYERGMHKIQSGIGRLILREEMKARSNSYADPWTPPRSSASSREALHTAGYEGSLNGSPRMHYLADSDPLISKSASLPAYRRNGLHRPPSAELFHYDSTNAVNWGMREYKIYPYELLLVKTRGRNQLPKDVDRTRLERHLSQEEFYQIFGMTIAEFDRLALWKRNELKKQARLF", "length": 687, "header": "tr|A0A8V0YF19-1|A0A8V0YF19_CHICK Isoform 1 of Actin binding LIM protein family member 3 OS=Gallus gallus OX=9031 GN=ABLIM3 PE=4 SV=1 CANONICAL=A0A8V0YF19-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Y8U4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF19/entry#A0A8V0Y8U4-1", "sequence": { "sequence": "MSTSIPYQQNPYTAGSGSTVIQCYRCGDTCKGEVVRVQSNHFHIRCFTCQVCGCDLAQSGFFFKNQEYICTHDYQQLYGTRCDSCGDFITGEVISALGRTYHPKCFVCSTCRKPFPIGDKVTFSGKDCVCQNCSHSLISTKPIKIHGPSHCAGCKEEIKQGQSLLALEKQWHVSCFKCQTCGIILTGEYISKDGVPYCESDYHAQFGIKCETCDRYISGRVLEAGGKHYHPTCARCVRCHQMFTEGEEMYLTGSEVWHPICKQAARAEKKLKHRRTSETSISPPGSSIGSPNRVICAKVDNEILNYKDLAALPKIKAIYEVQRPDLISYEPYHRYTSDETLERYSYGEDIYESFDIRQRRASSPGYIDSPTYSRQGMSPTIPRSPHHFYRSGTESGRSSPYYSQLDVRSSTPTSYQAPKHFHIPAAGESNIYRKPPIYKRHATKSKTSEDIAQSSKYSPAYSPDPYYHSESEYWSFQGSPKAPRARRFSSGGEEDGYERGMHKIQSGIGRLILREEMKARSNSYADPWTPPRSSASSREALHTAGYEGSLNGSPRMHYLADSDPLISKSASLPAYRRNGLHRPPSAELFHYDSTNAVNWGMREYKIYPYELLLVKTRGRNQLPKDVDRTRLERHLSQEEFYQIFGMTIAEFDRLALWKRNELKKQARLF", "length": 669, "header": "tr|A0A8V0Y8U4-1|A0A8V0Y8U4_CHICK Computationally mapped isoform of Actin binding LIM protein family member 3 OS=Gallus gallus OX=9031 GN=ABLIM3 PE=4 SV=1 CANONICAL=A0A8V0YF19-1" }, "locus": { "chromosome": "13", "start_pos": 8197829, "end_pos": 8163038, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029463.1", "url": "https://www.ensembl.org/id/ENSGALT00010029463.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017121.1", "url": "https://www.ensembl.org/id/ENSGALP00010017121.1" } ] } }, { "isoform_ac": "A0A8V0YDT9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF19/entry#A0A8V0YDT9-1", "sequence": { "sequence": "MSTSIPYQQNPYTAGSGSTVIQCYRCGDTCKGEVVRVQSNHFHIRCFTCQVCGCDLAQSGFFFKNQEYICTHDYQQLYGTRCDSCGDFITGEVISALGRTYHPKCFVCSTCRKPFPIGDKVTFSGKDCVCQNCSHSLISTKPIKIHGPSHCAGCKEEIKQGQSLLALEKQWHVSCFKCQTCGIILTGEYISKDGVPYCESDYHAQFGIKCETCDRYISGRVLEAGGKHYHPTCARCVRCHQMFTEGEEMYLTGSEVWHPICKQAARAEKKLKHRRTSETSISPPGSSIGSPNRVICDIYESFDIRQRRASSPGYIDSPTYSRQGMSPTIPRSPHHFYRSGTESGRSSPYYSQLDVRSSTPTSYQAPKHFHIPAAGESNIYRKPPIYKRHVAVDNISAATKSKTSEDIAQSSKYSPAYSPDPYYHSESEYWSFQGSPKAPRARRFSSGGEEDGYERGMHKIQSGIGRLILREEMKARSNSYADPWTPPRSSASSREALHTAGYEGSLNGSPRMHYLADSDPLISKSASLPAYRRNGLHRPPSAELFHYDSTNAVNWGMRGEAVGLGSRQGGGSAGAVGLPPCCRQLQKWDLDQRDKGRDGGVPAALEGAAGGEGAAAHVCFLFVSPTEYKVRWL", "length": 633, "header": "tr|A0A8V0YDT9-1|A0A8V0YF19_CHICK Computationally mapped isoform of Actin binding LIM protein family member 3 OS=Gallus gallus OX=9031 GN=ABLIM3 PE=4 SV=1 CANONICAL=A0A8V0YF19-1" }, "locus": { "chromosome": "13", "start_pos": 8197829, "end_pos": 8163935, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029435.1", "url": "https://www.ensembl.org/id/ENSGALT00010029435.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017100.1", "url": "https://www.ensembl.org/id/ENSGALP00010017100.1" } ] } }, { "isoform_ac": "A0A8V0YF19-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF19/entry#A0A8V0YF19-1", "sequence": { "sequence": "MSTSIPYQQNPYTAGSGSTVIQCYRCGDTCKGEVVRVQSNHFHIRCFTCQVCGCDLAQSGFFFKNQEYICTHDYQQLYGTRCDSCGDFITGEVISALGRTYHPKCFVCSTCRKPFPIGDKVTFSGKDCVCQNCSHSLISTKPIKIHGPSHCAGCKEEIKQGQSLLALEKQWHVSCFKCQTCGIILTGEYISKDGVPYCESDYHAQFGIKCETCDRYISGRVLEAGGKHYHPTCARCVRCHQMFTEGEEMYLTGSEVWHPICKQAARAEKKLKHRRTSETSISPPGSSIGSPNRVICAKVDNEILNYKDLAALPKIKAIYEVQRPDLISYEPYHRYTSDETLERYSYGESLGTLSPYSQDIYESFDIRQRRASSPGYIDSPTYSRQGMSPTIPRSPHHFYRSGTESGRSSPYYSQLDVRSSTPTSYQAPKHFHIPAAGESNIYRKPPIYKRHVAVDNISAATKSKTSEDIAQSSKYSPAYSPDPYYHSESEYWSFQGSPKAPRARRFSSGGEEDGYERGMHKIQSGIGRLILREEMKARSNSYADPWTPPRSSASSREALHTAGYEGSLNGSPRMHYLADSDPLISKSASLPAYRRNGLHRPPSAELFHYDSTNAVNWGMREYKIYPYELLLVKTRGRNQLPKDVDRTRLERHLSQEEFYQIFGMTIAEFDRLALWKRNELKKQARLF", "length": 687, "header": "tr|A0A8V0YF19-1|A0A8V0YF19_CHICK Isoform 1 of Actin binding LIM protein family member 3 OS=Gallus gallus OX=9031 GN=ABLIM3 PE=4 SV=1 CANONICAL=A0A8V0YF19-1" }, "locus": { "chromosome": "13", "start_pos": 8197829, "end_pos": 8163038, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029453.1", "url": "https://www.ensembl.org/id/ENSGALT00010029453.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017113.1", "url": "https://www.ensembl.org/id/ENSGALP00010017113.1" } ] } }, { "isoform_ac": "A0A8V0YH52-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF19/entry#A0A8V0YH52-1", "sequence": { "sequence": "MSTSIPYQQNPYTAGSGSTVIQCYRCGDTCKGEVVRVQSNHFHIRCFTCQVCGCDLAQSGFFFKNQEYICTHDYQQLYGTRCDSCGDFITGEVISALGRTYHPKCFVCSTCRKPFPIGDKVTFSGKDCVCQNCSHSLISTKPIKIHGPSHCAGCKEEIKQGQSLLALEKQWHVSCFKCQTCGIILTGEYISKDGVPYCESDYHAQFGIKCETCDRYISGRVLEAGGKHYHPTCARCVRCHQMFTEGEEMYLTGSEVWHPICKQAARAEKKLKHRRTSETSISPPGSSIGSPNRVICDIYESFDIRQRRASSPGYIDSPTYSRQGMSPTIPRSPHHFYRSAAGESNIYRKPPIYKRHVAVDNISAATKSKTSEDIAQSSKYSPAYSPDPYYHSESEYWSFQGSPKAPRARRFSSGGEEDGYERGMHKIQSGIGRLILREEMKARSNSYADPWTPPRSSASSREALHTAGYEGSLNGSPRMHYLADSDPLISKSASLPAYRRNGLHRPPSAELFHYDSTNAVNWGMRGEAVGLGSRQGGGSAGAVGLPPCCRQLQKWDLDQRDKGRDGGVPAALEGAAGGEGAAAHVCFLFVSPTEYKVRWL", "length": 600, "header": "tr|A0A8V0YH52-1|A0A8V0YH52_CHICK Computationally mapped isoform of Actin binding LIM protein family member 3 OS=Gallus gallus OX=9031 GN=ABLIM3 PE=4 SV=1 CANONICAL=A0A8V0YF19-1" }, "locus": { "chromosome": "13", "start_pos": 8197829, "end_pos": 8163935, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029441.1", "url": "https://www.ensembl.org/id/ENSGALT00010029441.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017104.1", "url": "https://www.ensembl.org/id/ENSGALP00010017104.1" } ] } }, { "isoform_ac": "A0A8V0YLX4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF19/entry#A0A8V0YLX4-1", "sequence": { "sequence": "MSTSIPYQQNPYTAGSGSTVIQCYRCGDTCKGEVVRVQSNHFHIRCFTCQVCGCDLAQSGFFFKNQEYICTHDYQQLYGTRCDSCGDFITGEVISALGRTYHPKCFVCSTCRKPFPIGDKVTFSGKDCVCQNCSHSLISTKPIKIHGPSHCAGCKEEIKQGQSLLALEKQWHVSCFKCQTCGIILTGEYISKDGVPYCESDYHAQFGIKCETCDRYISGRVLEAGGKHYHPTCARCVRCHQMFTEGEEMYLTGSEVWHPICKQAARAEKKLKHRRTSETSISPPGSSIGSPNRVICDIYESFDIRQRRASSPGYIDSPTYSRQGMSPTIPRSPHHFYRSGTESGRSSPYYSQLDVRSSTPTSYQAPKHFHIPAAGESNIYRKPPIYKRHDNISAATKSKTSEDIAQSSKYSPAYSPDPYYHSESEYWSFQGSPKAPRARRFSSGGEEDGYERGMHKIQSGIGRLILREEMKARSNSYADPWTPPRSSASSREALHTAGYEGSLNGSPRMHYLADSDPLISKSASLPAYRRNGLHRPPSAELFHYDSTNAVNWGMRGEAVGLGSRQGGGSAGAVGLPPCCRQLQKWDLDQRDKGRDGGVPAALEGAAGGEGAAAHVCFLFVSPTEYKVRWL", "length": 630, "header": "tr|A0A8V0YLX4-1|A0A8V0YLX4_CHICK Computationally mapped isoform of Actin binding LIM protein family member 3 OS=Gallus gallus OX=9031 GN=ABLIM3 PE=4 SV=1 CANONICAL=A0A8V0YF19-1" }, "locus": { "chromosome": "13", "start_pos": 8197829, "end_pos": 8163935, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029438.1", "url": "https://www.ensembl.org/id/ENSGALT00010029438.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017102.1", "url": "https://www.ensembl.org/id/ENSGALP00010017102.1" } ] } }, { "isoform_ac": "A0A8V0YLY0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF19/entry#A0A8V0YLY0-1", "sequence": { "sequence": "MSTSIPYQQNPYTAGSGSTVIQCYRCGDTCKGEVVRVQSNHFHIRCFTCQVCGCDLAQSGFFFKNQEYICTHDYQQLYGTRCDSCGDFITGEVISALGRTYHPKCFVCSTCRKPFPIGDKVTFSGKDCVCQNCSHSLISTKPIKIHGPSHCAGCKEEIKQGQSLLALEKQWHVSCFKCQTCGIILTGEYISKDGVPYCESDYHAQFGIKCETCDRYISGRVLEAGGKHYHPTCARCVRCHQMFTEGEEMYLTGSEVWHPICKQAARAEKKLKHRRTSETSISPPGSSIGSPNRVICDIYESFDIRQRRASSPGYIDSPTYSRQGMSPTIPRSPHHFYRSGTESGRSSPYYSQLDVRSSTPTSYQAPKHFHIPAAGESNIYRKPPIYKRHATKSKTSEDIAQSSKYSPAYSPDPYYHSESEYWSFQGSPKAPRARRFSSGGEEDGYERGMHKIQSGIGRLILREEMKARSNSYADPWTPPRSSASSREALHTAGYEGSLNGSPRMHYLADSDPLISKSASLPAYRRNGLHRPPSAELFHYDSTNAVNWGMRGEAPRCATQAPQNEAGGGIALSSECREPPWCCCPCTDLPL", "length": 590, "header": "tr|A0A8V0YLY0-1|A0A8V0YLY0_CHICK Computationally mapped isoform of Actin binding LIM protein family member 3 OS=Gallus gallus OX=9031 GN=ABLIM3 PE=4 SV=1 CANONICAL=A0A8V0YF19-1" }, "locus": { "chromosome": "13", "start_pos": 8197829, "end_pos": 8163453, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029445.1", "url": "https://www.ensembl.org/id/ENSGALT00010029445.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017107.1", "url": "https://www.ensembl.org/id/ENSGALP00010017107.1" } ] } }, { "isoform_ac": "A0A8V0YLY9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF19/entry#A0A8V0YLY9-1", "sequence": { "sequence": "MSTSIPYQQNPYTAGSGSTVIQCYRCGDTCKGEVVRVQSNHFHIRCFTCQVCGCDLAQSGFFFKNQEYICTHDYQQLYGTRCDSCGDFITGEVISALGRTYHPKCFVCSTCRKPFPIGDKVTFSGKDCVCQNCSHSLISTKPIKIHGPSHCAGCKEEIKQGQSLLALEKQWHVSCFKCQTCGIILTGEYISKDGVPYCESDYHAQFGIKCETCDRYISGRVLEAGGKHYHPTCARCVRCHQMFTEGEEMYLTGSEVWHPICKQAARAEKKLKHRRTSETSISPPGSSIGSPNRVICAKVDNEILNYKDLAALPKIKAIYEVQRPDLISYEPYHRYTSDETLERYSYGESLGTLSPYSQDIYESFDIRQRRASSPGYIDSPTYSRQGMSPTIPRSPHHFYRSDNISAATKSKTSEDIAQSSKYSPAYSPDPYYHSESEYWSFQGSPKAPRARRFSSGGEEDGYERGMHKIQSGIGRLILREEMKARSNSYADPWTPPRSSASSREALHTAGYEGSLNGSPRMHYLADSDPLISKSASLPAYRRNGLHRPPSAELFHYDSTNAVNWGMREYKIYPYELLLVKTRGRNQLPKDVDRTRLERHLSQEEFYQIFGMTIAEFDRLALWKRNELKKQARLF", "length": 634, "header": "tr|A0A8V0YLY9-1|A0A8V0YLY9_CHICK Computationally mapped isoform of Actin binding LIM protein family member 3 OS=Gallus gallus OX=9031 GN=ABLIM3 PE=4 SV=1 CANONICAL=A0A8V0YF19-1" }, "locus": { "chromosome": "13", "start_pos": 8197829, "end_pos": 8163038, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029457.1", "url": "https://www.ensembl.org/id/ENSGALT00010029457.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017117.1", "url": "https://www.ensembl.org/id/ENSGALP00010017117.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YF19", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF19" } ], "pmid": "" }, { "name": "actin filament binding", "id": "GO:0051015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051015", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YF19", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF19" } ], "pmid": "" }, { "name": "actin binding", "id": "GO:0003779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003779", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YF19", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF19" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "glutamatergic synapse", "id": "GO:0098978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098978", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YF19", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF19" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YF19", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF19" } ], "pmid": "" }, { "name": "actin cytoskeleton", "id": "GO:0015629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015629", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YF19", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF19" } ], "pmid": "" }, { "name": "lamellipodium", "id": 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"sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YF96-1", "uniprot_ac": "A0A8V0YF96", "uniprot_id": "A0A8V0YF96_CHICK", "mass": { "chemical_mass": 84715.0, "monoisotopic_mass": 84715.0 }, "refseq": {}, "gene_names": [ { "name": "MLPH", "type": "recommended", "evidence": [ { "id": "A0A8V0YF96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF96" } ] } ], "protein_names": [ { "name": "Melanophilin", "type": "synonym", "evidence": [ { "id": "A0A8V0YF96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF96/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YF96", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF96" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": 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"database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHC9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHC9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHC9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHC9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKIRKGLLFILFLILSFFSYMQYRNSHSEAQGVFVLPRGQMANTATRPALLIGLLQFKYVPPGSPCKMGRKLDLSKLTDEEAKHVWEVVQRDFDLRKKEEERLEDLKCKIDQESSKREFLTHQSHLNETHCVHCLQPFKFLLNSKRQCLDCRFYTCKSCSRYNKREQGWVCDPCRLSRVVKIGSLEWYYEHVRSRFKRFGSAKVLQSLYGRLQPGQKGNSALLGLHDRVYSLPDINSECQLPANGGIGDDSEDEDDALHGAEAECYSRMRKTKRLLSVHPFDFELDSDYSAQSRRQSAQLSPVAINSPDAFQSFPDFSGPPEDAPREPRLEEADLAAVFHILREQEQHLSPPEQHFSTEVRLTLNARRRSLDRSSKPGSPWVEQPRSPYSADMDTSDEDVKGAPKLTACLPHYLKRRSRASSQENISHNSGSQIHELNKRMSVIERVLNRLEEKLLVRSAESPATESQLDPDAEEEELKRKLEEFTSHISDREVSSEEEGREERKEVKRPEMNSSSDDIASEARKRSSAQSLSEITAKALRAINATEKAVSESLQGQSWGSDGCALHLSMEDGKEAAEAYRKLEENVYLTAGKAYQLETTLTELEEGAQHCGTTDLELSELEDKVASAAAQVQQAESEISDIESRIAALSAAGLTVKPLEKARKKSNGQAFHLCSPNLASSPGESLDDVKAMSGPQVLRRRFNSPFEIAGLDDSFDRNSVYRGSLTQRNPNGKNRRVERLFAKPVMTHLS", "length": 750, "header": "tr|A0A8V0YF96-1|A0A8V0YF96_CHICK Isoform 1 of Melanophilin OS=Gallus gallus OX=9031 GN=MLPH PE=1 SV=1 CANONICAL=A0A8V0YF96-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Y8Y1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF96/entry#A0A8V0Y8Y1-1", "sequence": { "sequence": "MGCRHGQTEACRDLKCKIDQESSKREFLTHQSHLNETHCVHCLQPFKFLLNSKRQCLDCRFYTCKSCSRYNKREQGWVCDPCRLSRVVKIGSLEWYYEHVRSRFKRFGSAKVLQSLYGRLQPGQKGNSALLGLHDRVYSLPDINSECQLPANGGIGDDSEDEDDALHGAEAECYSRMRKTKRLLSVHPFDFELDSDYSAQSRRQSAQLSPVAINSPDAFQSFPDFSGPPEDAPREPRLEEADLAAVFHILREQEQHLSPPEQHFSTEVRLTLNARRRSLDRSSKPGSPWVEQPRSPYSADMDTSDEDVKGAPKLTACLPHYLKRRSRASSQENISHNSGSQIHELNKRMSVIERVLNRLEEKLLVRSAESPATESQLDPDAEEEELKRKLEEFTSHISDREVSSEEEGREERKEVKRPEMNSSSDDIASEARKRSSAQSLSEITAKALRAINATEKAVSESLQGQSWGSDGCALHLSMEDGKEAAEAYRKLEENVYLTAGKAYQLETTLTELEEGAQHCGTTDLELSELEDKVASAAAQVQQAESEISDIESRIAALSAAGLTVKPLEKARKKSNGQAFHLCSPNLASSPGESLDDVKTAFPLLQAMSGPQVLRRRFNSPFEIAGLDDSFDRNSVYRGSLTQRNPNGKNRRVERLFAKPVMTHLS", "length": 665, "header": "tr|A0A8V0Y8Y1-1|A0A8V0Y8Y1_CHICK Computationally mapped isoform of Melanophilin OS=Gallus gallus OX=9031 GN=MLPH PE=1 SV=1 CANONICAL=A0A8V0YF96-1" }, "locus": { "chromosome": "7", "start_pos": 4864226, "end_pos": 4849531, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029516.1", "url": "https://www.ensembl.org/id/ENSGALT00010029516.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017156.1", "url": "https://www.ensembl.org/id/ENSGALP00010017156.1" } ] } }, { "isoform_ac": "A0A8V0Y8Z6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF96/entry#A0A8V0Y8Z6-1", "sequence": { "sequence": "MGRKLDLSKLTDEEAKHVWEVVQRDFDLRKKEEERLEDLKCKIDQESSKREFLTHQSHLNETHCVHCLQPFKFLLNSKRQCLDCRFYTCKSCSRYNKREQGWVCDPCRLSRVVKIGSLEWYYEHVRSRFKRFGSAKVLQSLYGRLQPGQKGNSALLGLHDRVYSLPDINSECQLPANGGIGDDSEDEDDALHGAEAECYSRMRKTKRLLSVHPFDFELDSDYSAQSRRQSAQLSPVAINSPDAFQSFPDFSGPPEDAPREPRLEEADLAAVFHILREQEQHLSPPEQHFSTEVRLTLNARRRSLDRSSKPGSPWVEQPRSPYSADMDTSDEDVKGAPKLTACLPHYLKRRSRASSQENISHNSGSQIHELNKRMSVIERVLNRLEEKLLVRSAESPATESQLDPDAEEEELKRKLEEFTSHISDREVSSEEEGREERKEVKRPEMNSSSDDIASEARKVYLTAGKAYQLETTLTELEEGAQHCGTTDLELSELEDKVASAAAQVQQAESEISDIESRIAALSAAGLTVKPLEKARKKSNGQAFHLCSPNLASSPGESLDDVKAMSGPQVLRRRFNSPFEIAGLDDSFDRNSVYRGSLTQRNPNGKNRRVERLFAKPVMTHLS", "length": 622, "header": "tr|A0A8V0Y8Z6-1|A0A8V0Y8Z6_CHICK Computationally mapped isoform of Melanophilin OS=Gallus gallus OX=9031 GN=MLPH PE=1 SV=1 CANONICAL=A0A8V0YF96-1" }, "locus": { "chromosome": "7", "start_pos": 4866796, "end_pos": 4849531, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029541.1", "url": "https://www.ensembl.org/id/ENSGALT00010029541.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017172.1", "url": "https://www.ensembl.org/id/ENSGALP00010017172.1" } ] } }, { "isoform_ac": "A0A8V0Y901-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF96/entry#A0A8V0Y901-1", "sequence": { "sequence": "MKIRKGLLFILFLILSFFSYMQYRNSHSEAQGVFVLPRGQMANTATRPALLIGLLQFKYVPPGSPCKMGRKLDLSKLTDEEAKHVWEVVQRDFDLRKKEEERLEDLKCKIDQESSKREFLTHQSHLNETHCVHCLQPFKFLLNSKRQCLDCRFYTCKSCSRYNKREQGWVCDPCRLSRVVKIGSLEWYYEHVRSRFKRFGSAKVLQSLYGRLQPGQKGNSALLGLHDRVYSLPDINSECQLPANGGIGDDSEDEDDALHGAEAECYSRSFPDFSGPPEDAPREPRLEEADLAAVFHILREQEQHLSPPEQHFSTEVRLTLNARRRSLDRSSKPGSPWVEQPRSPYSADMDTSDEDVKGAPKLTACLPHYLKRRSRASSQENISHNSGSQSPATESQLDPDAEEEELKRKLEEFTSHISDREVSSEEEGREERKEVKRPEMNSSSDDIASEARKRSSAQSLSEITAKALRAINATEKAVSESLQGQSWGSDGCALHLSMEDGKEAAEAYRKLEENVYLTAGKAYQLETTLTELEEGAQHCGTTDLELSELEDKVASAAAQVQQAESEISDIESRIAALSAAGLTVKPLEKARKKSNGQAFHLCSPNLASSPGESLDDVKAMSGPQVLRRRFNSPFEIAGLDDSFDRNSVYRGSLTQRNPNGKNRRVERLFAKPVMTHLS", "length": 678, "header": "tr|A0A8V0Y901-1|A0A8V0Y901_CHICK Computationally mapped isoform of Melanophilin OS=Gallus gallus OX=9031 GN=MLPH PE=1 SV=1 CANONICAL=A0A8V0YF96-1" }, "locus": { "chromosome": "7", "start_pos": 4867527, "end_pos": 4849531, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029551.1", "url": "https://www.ensembl.org/id/ENSGALT00010029551.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017178.1", "url": "https://www.ensembl.org/id/ENSGALP00010017178.1" } ] } }, { "isoform_ac": "A0A8V0Y911-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF96/entry#A0A8V0Y911-1", "sequence": { "sequence": "MQLSIRRSRSRGCVPHTLCPSGNQHLPLRLRFLMHPAQSKLARDDLKGSPCKMGRKLDLSKLTDEEAKHVWEVVQRDFDLRKKEEERLEDLKCKIDQESSKREFLTHQSHLNETHCVHCLQPFKFLLNSKRQCLDCRFYTCKSCSRYNKREQGWVCDPCRLSRVVKIGSLEWYYEHVRSRFKRFGSAKVLQSLYGRLQPGQKGNSALLGLHDRVYSLPDINSECQLPANGGIGDDSEDEDDALHGAEAECYSRMRKTKRLLSVHPFDFELDSDYSAQSRRQSAQLSPVAINSPDAFQSFPDFSGPPEDAPREPRLEEADLAAVFHILREQEQHLSPPEQHFSTEVRLTLNARRRSLDRSSKPGSPWVEQPRSPYSADMDTSDEDVKGAPKLTACLPHYLKRRSRASSQENISHNSGSQSPATESQLDPDAEEEELKRKLEEFTSHISDREVSSEEEGREERKEVKRPEMNSSSDDIASEARKRSSAQSLSEITAKALRAINATEKAVSESLQGQSWGSDGCALHLSMEDGKEAAEAYRKLEENVYLTAGKAYQLETTLTELEEGAQHCGTTDLELSELEDKVASAAAQISDIESRIAALSAAGLTVKPLEKARKKSNGQAFHLCSPNLASSPGESLDDVKAMSGPQVLRRRFNSPFEIAGLDDSFDRNSVYRGSLTQRNPNGKNRRVERLFAKPVMTHLS", "length": 700, "header": "tr|A0A8V0Y911-1|A0A8V0Y911_CHICK Computationally mapped isoform of Melanophilin OS=Gallus gallus OX=9031 GN=MLPH PE=1 SV=1 CANONICAL=A0A8V0YF96-1" }, "locus": { "chromosome": "7", "start_pos": 4879515, "end_pos": 4849531, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029561.1", "url": "https://www.ensembl.org/id/ENSGALT00010029561.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017188.1", "url": "https://www.ensembl.org/id/ENSGALP00010017188.1" } ] } }, { "isoform_ac": "A0A8V0YDY9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF96/entry#A0A8V0YDY9-1", "sequence": { "sequence": "MQKSEWDLKCKIDQESSKREFLTHQSHLNETHCVHCLQPFKFLLNSKRQCLDCRFYTCKSCSRYNKREQGWVCDPCRLSRVVKIGSLEWYYEHVRSRFKRFGSAKVLQSLYGRLQPGQKGNSALLGLHDRVYSLPDINSECQLPANGGIGDDSEDEDDALHGAEAECYSRSFPDFSGPPEDAPREPRLEEADLAAVFHILREQEQHLSPPEQHFSTEVRLTLNARRRSLDRSSKPGSPWVEQPRSPYSADMDTSDEDVKGAPKLTACLPHYLKRRSRASSQENISHNSGSQIHELNKRMSVIERVLNRLEEKLLVRSAESPATESQLDPDAEEEELKRKLEEFTSHISDREVSSEEEGREERKEVKRPEMNSSSDDIASEARKRSSAQSLSEITAKALRAINATEKAVSESLQGQSWGSDGCALHLSMEDGKEAAEAYRKLEENVYLTAGKAYQLETTLTELEEGAQHCGTTDLELSELEDKVASAAAQVQQAESEISDIESRIAALSAAGLTVKPLEKARKKSNGQAFHLCSPNLASSPGESLDDVKAMSGPQVLRRRFNSPFEIAGLDDSFDRNSVYRGSLTQRNPNGKNRRVERLFAKPVMTHLS", "length": 608, "header": "tr|A0A8V0YDY9-1|A0A8V0YF96_CHICK Computationally mapped isoform of Melanophilin OS=Gallus gallus OX=9031 GN=MLPH PE=1 SV=1 CANONICAL=A0A8V0YF96-1" }, "locus": { "chromosome": "7", "start_pos": 4863015, "end_pos": 4849531, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029508.1", "url": "https://www.ensembl.org/id/ENSGALT00010029508.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017150.1", "url": "https://www.ensembl.org/id/ENSGALP00010017150.1" } ] } }, { "isoform_ac": "A0A8V0YF61-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF96/entry#A0A8V0YF61-1", "sequence": { "sequence": "MDERSVPRAQRDLKCKIDQESSKREFLTHQSHLNETHCVHCLQPFKFLLNSKRQCLDCRFYTCKSCSRYNKREQGWVCDPCRLSRVVKIGSLEWYYEHVRSRFKRFGSAKVLQSLYGRLQPGQKGNSALLGLHDRVYSLPDINSECQLPANGGIGDDSEDEDDALHGAEAECYSRSFPDFSGPPEDAPREPRLEEADLAAVFHILREQEQHLSPPEQHFSTEVRLTLNARRRSLDRSSKPGSPWVEQPRSPYSADMDTSDEDVKGAPKLTACLPHYLKRRSRASSQENISHNSGSQSPATESQLDPDAEEEELKRKLEEFTSHISDREVSSEEEGREERKEVKRPEMNSSSDDIASEARKRSSAQSLSEITAKALRAINATEKAVSESLQGQSWGSDGCALHLSMEDGKEAAEAYRKLEENVYLTAGKAYQLETTLTELEEGAQHCGTTDLELSELEDKVASAAAQVQQAESEISDIESRIAALSAAGLTVKPLEKARKKSNGQAFHLCSPNLASSPGESLDDVKAMSGPQVLRRRFNSPFEIAGLDDSFDRNSVYRGSLTQRNPNGKNRRVERLFAKPVMTHLS", "length": 585, "header": "tr|A0A8V0YF61-1|A0A8V0YF61_CHICK Computationally mapped isoform of Melanophilin OS=Gallus gallus OX=9031 GN=MLPH PE=1 SV=1 CANONICAL=A0A8V0YF96-1" }, "locus": { "chromosome": "7", "start_pos": 4863974, "end_pos": 4849531, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029511.1", "url": "https://www.ensembl.org/id/ENSGALT00010029511.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017153.1", "url": "https://www.ensembl.org/id/ENSGALP00010017153.1" } ] } }, { "isoform_ac": "A0A8V0YF96-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF96/entry#A0A8V0YF96-1", "sequence": { "sequence": "MKIRKGLLFILFLILSFFSYMQYRNSHSEAQGVFVLPRGQMANTATRPALLIGLLQFKYVPPGSPCKMGRKLDLSKLTDEEAKHVWEVVQRDFDLRKKEEERLEDLKCKIDQESSKREFLTHQSHLNETHCVHCLQPFKFLLNSKRQCLDCRFYTCKSCSRYNKREQGWVCDPCRLSRVVKIGSLEWYYEHVRSRFKRFGSAKVLQSLYGRLQPGQKGNSALLGLHDRVYSLPDINSECQLPANGGIGDDSEDEDDALHGAEAECYSRMRKTKRLLSVHPFDFELDSDYSAQSRRQSAQLSPVAINSPDAFQSFPDFSGPPEDAPREPRLEEADLAAVFHILREQEQHLSPPEQHFSTEVRLTLNARRRSLDRSSKPGSPWVEQPRSPYSADMDTSDEDVKGAPKLTACLPHYLKRRSRASSQENISHNSGSQIHELNKRMSVIERVLNRLEEKLLVRSAESPATESQLDPDAEEEELKRKLEEFTSHISDREVSSEEEGREERKEVKRPEMNSSSDDIASEARKRSSAQSLSEITAKALRAINATEKAVSESLQGQSWGSDGCALHLSMEDGKEAAEAYRKLEENVYLTAGKAYQLETTLTELEEGAQHCGTTDLELSELEDKVASAAAQVQQAESEISDIESRIAALSAAGLTVKPLEKARKKSNGQAFHLCSPNLASSPGESLDDVKAMSGPQVLRRRFNSPFEIAGLDDSFDRNSVYRGSLTQRNPNGKNRRVERLFAKPVMTHLS", "length": 750, "header": "tr|A0A8V0YF96-1|A0A8V0YF96_CHICK Isoform 1 of Melanophilin OS=Gallus gallus OX=9031 GN=MLPH PE=1 SV=1 CANONICAL=A0A8V0YF96-1" }, "locus": { "chromosome": "7", "start_pos": 4867527, "end_pos": 4849531, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029558.1", "url": "https://www.ensembl.org/id/ENSGALT00010029558.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017185.1", "url": "https://www.ensembl.org/id/ENSGALP00010017185.1" } ] } }, { "isoform_ac": "A0A8V0YHB2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF96/entry#A0A8V0YHB2-1", "sequence": { "sequence": "MGRKLDLSKLTDEEAKHVWEVVQRDFDLRKKEEERLEDLKCKIDQESSKREFLTHQSHLNETHCVHCLQPFKFLLNSKRQCLDCRFYTCKSCSRYNKREQGWVCDPCRLSRVVKIGSLEWYYEHVRSRFKRFGSAKVLQSLYGRLQPGQKGNSALLGLHDRVYSLPDINSECQLPANGGIGDDSEDEDDALHGAEAECYSRMRKTKRLLSVHPFDFELDSDYSAQSRRQSAQLSPVAINSPDAFQSFPDFSGPPEDAPREPRLEEADLAAVFHILREQEQHLSPPEQHFSTEVRLTLNARRRSLDRSSKPGSPWVEQPRSPYSADMDTSDEDVKGAPKLTACLPHYLKRRSRASSQENISHNSGSQSPATESQLDPDAEEEELKRKLEEFTSHISDREVSSEEEGREERKEVKRPEMNSSSDDIASEARKRSSAQSLSEITAKALRAINATEKAVSESLQGQSWGSDGCALHLSMEDGKEAAEAYRKLEENVYLTAGKAYQLETTLTELEEGAQHCGTTDLELSELEDKVASAAAQVQQAESEISDIESRIAALSAAGLTVKPLEKARKKSNGQAFHLCSPNLASSPGESLDDVKAMSGPQVLRRRFNSPFEIAGLDDSFDRNSVYRGSLTQRNPNGKNRRVERLFAKPVMTHLS", "length": 655, "header": "tr|A0A8V0YHB2-1|A0A8V0YHB2_CHICK Computationally mapped isoform of Melanophilin OS=Gallus gallus OX=9031 GN=MLPH PE=1 SV=1 CANONICAL=A0A8V0YF96-1" }, "locus": { "chromosome": "7", "start_pos": 4866796, "end_pos": 4849531, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029527.1", "url": "https://www.ensembl.org/id/ENSGALT00010029527.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017164.1", "url": "https://www.ensembl.org/id/ENSGALP00010017164.1" } ] } }, { "isoform_ac": "A0A8V0YHC9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF96/entry#A0A8V0YHC9-1", "sequence": { "sequence": "MKIRKGLLFILFLILSFFSYMQYRNSHSEAQGVFVLPRGQMANTATRPALLIGLLQFKYVPPGSPCKMGRKLDLSKLTDEEAKHVWEVVQRDFDLRKKEEERLEDLKCKIDQESSKREFLTHQSHLNETHCVHCLQPFKFLLNSKRQCLDCRFYTCKSCSRYNKREQGWVCDPCRLSRVVKIGSLEWYYEHVRSRFKRFGSAKVLQSLYGRLQPGQKGNSALLGLHDRVYSLPDINSECQLPANGGIGDDSEDEDDALHGAEAECYSRMRKTKRLLSVHPFDFELDSDYSAQSRRQSAQLSPVAINSPDAFQSFPDFSGPPEDAPREPRLEEADLAAVFHILREQEQHLSPPEQHFSTEVRLTLNARRRSLDRSSKPGSPWVEQPRSPYSADMDTSDEDVKGAPKLTACLPHYLKRRSRASSQENISHNSGSQSPATESQLDPDAEEEELKRKLEEFTSHISDREVSSEEEGREERKEVKRPEMNSSSDDIASEARKRSSAQSLSEITAKALRAINATEKAVSESLQGQSWGSDGCALHLSMEDGKEAAEAYRKLEENVYLTAGKAYQLETTLTELEEGAQHCGTTDLELSELEDKVASAAAQVQQAESEISDIESRIAALSAAGLTVKPLEKARKKSNGQAFHLCSPNLASSPGESLDDVKAMSGPQVLRRRFNSPFEIAGLDDSFDRNSVYRGSLTQRNPNGKNRRVERLFAKPVMTHLS", "length": 722, "header": "tr|A0A8V0YHC9-1|A0A8V0YHC9_CHICK Computationally mapped isoform of Melanophilin OS=Gallus gallus OX=9031 GN=MLPH PE=1 SV=1 CANONICAL=A0A8V0YF96-1" }, "locus": { "chromosome": "7", "start_pos": 4867527, "end_pos": 4849531, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029554.1", "url": "https://www.ensembl.org/id/ENSGALT00010029554.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017181.1", "url": "https://www.ensembl.org/id/ENSGALP00010017181.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-9824585", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9824585", "resource": "Reactome", "description": "Regulation of MITF-M-dependent genes involved in pigmentation" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YF96", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF96" } ], "pmid": "" }, { "name": "actin binding", "id": "GO:0003779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003779", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YF96", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF96" } ], "pmid": "" }, { "name": "protein-macromolecule adaptor activity", "id": "GO:0030674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030674", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YF96", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF96" } ], "pmid": "" }, { "name": "myosin binding", "id": "GO:0017022", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017022", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YF96", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF96" } ], "pmid": "" }, { "name": "small GTPase binding", "id": "GO:0031267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031267", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YF96", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF96" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "intracellular protein transport", "id": "GO:0006886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YF96", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF96" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "dendrite", "id": "GO:0030425", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030425", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YF96", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF96" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YF96", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF96" } ], "pmid": "" }, { "name": "cortical actin cytoskeleton", "id": "GO:0030864", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030864", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YF96", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF96" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YF96", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF96" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 127, "end_pos": 129, "annotation": "n_glycosylation_sequon" }, { "start_pos": 425, "end_pos": 427, "annotation": "n_glycosylation_sequon" }, { "start_pos": 513, "end_pos": 515, "annotation": "n_glycosylation_sequon" }, { "start_pos": 544, "end_pos": 546, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YF96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF96" }, { "id": "PS50916", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50916" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RabBD", "eco_id": "ECO_0000259", "start_pos": 71, "end_pos": 191, "start_aa": "Lys", "end_aa": "His", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 127, "end_pos": 129 }, { "start_pos": 425, "end_pos": 427 }, { "start_pos": 513, "end_pos": 515 }, { "start_pos": 544, "end_pos": 546 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YHC3-1", "uniprot_ac": "A0A8V0YHC3", "uniprot_id": "A0A8V0YHC3_CHICK", "mass": { "chemical_mass": 54909.0, "monoisotopic_mass": 54909.0 }, "refseq": {}, "gene_names": [ { "name": "BCL2L13", "type": "recommended", "evidence": [ { "id": "A0A8V0YHC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHC3" } ] } ], "protein_names": [ { "name": "BCL2 like 13", "type": "synonym", "evidence": [ { "id": "A0A8V0YHC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHC3/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHC3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHC3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "BCL2L13", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHC3", "locus": { "chromosome": "1", "start_pos": 61900688, "end_pos": 61857683, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012343", "url": "https://www.ensembl.org/id/ENSGALG00010012343" } ] } } ], "crossref": [ { "id": "A0A8V0YHC3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YHC3", "database": "AlphaFoldDB", "categories": [] }, { "id": "418163", "url": "https://www.ncbi.nlm.nih.gov/gene/418163", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002475", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002475", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036834", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036834", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042398", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042398", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046371", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046371", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "MHEALQT", "url": "https://omabrowser.org/oma/group/MHEALQT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YE13", "url": "https://www.orthodb.org/?gene=A0A8V0YE13", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YF91", "url": "https://www.orthodb.org/?gene=A0A8V0YF91", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YHC3", "url": "https://www.orthodb.org/?gene=A0A8V0YHC3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15758", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15758", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15758:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15758:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00452", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00452", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YE13", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE13", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YE13-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE13-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YF91", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF91", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YF91-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF91-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHC3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHC3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHC3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHC3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDAALIHLQLGSCSVTQRKPYVPHKSTNKLQANPMASSTAVPVGFHYETKYVVLSYLGLLSQEKPQEHPPASTQGTQQQLTAQHASEKEALEKIKIEIEEELKHLDEEILEAFTTTGFDCHTSPVFSPVNPESSIEDCLAHLGEKVSQELKEHLHKALESLLSKPVTYQEYRERTQETAAHASGWNKVLVPLVLLQQFLMELTRRGQEPLSALVNFGVTYLEDYSADYIIQQGGWGTVFSLESEEEEYPGLIAEDSNDIYILTSDNSGQVSPPESPTVTTSWQSESLPVSLSASQSWHTESLPVSLGPESWQQVAMDPEEVKSLDSNGGAEERSENNSSNSDIVHVEKEEIPEGIEEAVVSAVAAETVQAAFPETPASLQEVKPQAEIVAVEKAHPSARRTKQEEKGKVAEELVEPEIPALSKPVPKLTPSEGKATPEPEKILLPGEKKVGKEGPLEEIEEKSSAAEEKPILLPEGKSILLYGGAAAVAILAVAVGVALALRKK", "length": 504, "header": "tr|A0A8V0YHC3-1|A0A8V0YHC3_CHICK Isoform 1 of BCL2 like 13 OS=Gallus gallus OX=9031 GN=BCL2L13 PE=1 SV=1 CANONICAL=A0A8V0YHC3-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YE13-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHC3/entry#A0A8V0YE13-1", "sequence": { "sequence": "MASSTAVPVGFHYETKYVVLSYLGLLSQEKPQEHPPASTQGTQQQLTAQHASEKEALEKIKIEIEEELKHLDEEILEAFTTTGFDCHTSPVFSPVNPESSIEDCLAHLGEKVSQELKEHLHKALESLLSKPVTYQEYRERTQETAAHASGWNKVLVPLVLLQQFLMELTRRGQEPLSALVNFGVTYLEDYSADYIIQQGGWGTVFSLESEEEEYPGLIAEDSNDIYILTSDNSGQVSPPESPTVTTSWQSESLPVSLSASQSWHTESLPVSLGPESWQQVAMDPEEVKSLDSNGGAEERSENNSSNSDIVHVEKEEIPEGIEEAVVSAVAAETVQAAFPETPASLQEVKPQAEIVAVEKAHPSARRTKQEEKGKVAEELVEPEIPALSKPVPKLTPSEGKATPEPEKILLPGEKKVGKEGPLEEIEGKSILLYGGAAAVAILAVAVGVALALRKK", "length": 455, "header": "tr|A0A8V0YE13-1|A0A8V0YHC3_CHICK Computationally mapped isoform of BCL2 like 13 OS=Gallus gallus OX=9031 GN=BCL2L13 PE=1 SV=1 CANONICAL=A0A8V0YHC3-1" }, "locus": { "chromosome": "1", "start_pos": 61894962, "end_pos": 61862474, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029540.1", "url": "https://www.ensembl.org/id/ENSGALT00010029540.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017171.1", "url": "https://www.ensembl.org/id/ENSGALP00010017171.1" } ] } }, { "isoform_ac": "A0A8V0YF91-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHC3/entry#A0A8V0YF91-1", "sequence": { "sequence": "MASSTAVPVGFHYETKYVVLSYLGLLSQEKPQEHPPASTQGTQQQLTAQHASEKEALEKIKIEIEEELKHLDEEILEAFTTTGFDCHTSPVFSPVNPESSIEDCLAHLGEKVSQELKEHLHKALESLLSKPVTYQEYRERTQETAAHASGWNKVLVPLVLLQQFLMELTRRGQEPLSALVNFGVTYLEDYSADYIIQQGGWGTVFSLESEEEEYPGLIAEDSNDIYILTSDNSGQVSPPESPTVTTSWQSESLPVSLSASQSWHTESLPVSLGPESWQQVAMDPEEVKSLDSNGGAEERSENNSSNSDIVHVEKEEIPEGIEEAVVSAVAAETVQAAFPETPASLQEVKPQAEIVAVEKAHPSARRTKQEEKGKVAEELVEPEIPALSKPVPKLTPSEGKATPEPEKILLPGEKKVGKEGPLEEIEEKSSAAEEKPILLPEGKSILLYGGAAAVAILAVAVGVALALRKK", "length": 470, "header": "tr|A0A8V0YF91-1|A0A8V0YF91_CHICK Computationally mapped isoform of BCL2 like 13 OS=Gallus gallus OX=9031 GN=BCL2L13 PE=1 SV=1 CANONICAL=A0A8V0YHC3-1" }, "locus": { "chromosome": "1", "start_pos": 61894962, "end_pos": 61862474, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029552.1", "url": "https://www.ensembl.org/id/ENSGALT00010029552.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017180.1", "url": "https://www.ensembl.org/id/ENSGALP00010017180.1" } ] } }, { "isoform_ac": "A0A8V0YHC3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHC3/entry#A0A8V0YHC3-1", "sequence": { "sequence": "MDAALIHLQLGSCSVTQRKPYVPHKSTNKLQANPMASSTAVPVGFHYETKYVVLSYLGLLSQEKPQEHPPASTQGTQQQLTAQHASEKEALEKIKIEIEEELKHLDEEILEAFTTTGFDCHTSPVFSPVNPESSIEDCLAHLGEKVSQELKEHLHKALESLLSKPVTYQEYRERTQETAAHASGWNKVLVPLVLLQQFLMELTRRGQEPLSALVNFGVTYLEDYSADYIIQQGGWGTVFSLESEEEEYPGLIAEDSNDIYILTSDNSGQVSPPESPTVTTSWQSESLPVSLSASQSWHTESLPVSLGPESWQQVAMDPEEVKSLDSNGGAEERSENNSSNSDIVHVEKEEIPEGIEEAVVSAVAAETVQAAFPETPASLQEVKPQAEIVAVEKAHPSARRTKQEEKGKVAEELVEPEIPALSKPVPKLTPSEGKATPEPEKILLPGEKKVGKEGPLEEIEEKSSAAEEKPILLPEGKSILLYGGAAAVAILAVAVGVALALRKK", "length": 504, "header": "tr|A0A8V0YHC3-1|A0A8V0YHC3_CHICK Isoform 1 of BCL2 like 13 OS=Gallus gallus OX=9031 GN=BCL2L13 PE=1 SV=1 CANONICAL=A0A8V0YHC3-1" }, "locus": { "chromosome": "1", "start_pos": 61894962, "end_pos": 61858487, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029547.1", "url": "https://www.ensembl.org/id/ENSGALT00010029547.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017176.1", "url": "https://www.ensembl.org/id/ENSGALP00010017176.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A5G2QSZ0-1", "protein_name": "BCL2 like 13", "gene_name": "BCL2L13", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "VSTTVPLGFHYETKYVVLSYLGLLSQEKLQEHLSLPQGFQDIASQPLDPEVLLKVKTEIEEELKSLDKEISEAFTSTGFDRHTSPVFSPANPESSLEDCLAHLGEKASQELKVPLLGALQVLLSRPVTYQAYRECTLETTVHASGWNKILVPLILLRQMLLELTRRGQEPLGALLQFGVTYLEDHAAEYIIQQGGWGTVFNLESEDEECPAGTAEDSNDIYILPSDSSAHVSPPESPTAAASWQAESLPVSLSASQSWHTESMPVSLGPESWQQVTVDPEEVKSLDSNGAGEKSENNSSNSDIVHVEKEEIPEGVEEAAMAARALPAGELPEVAPGAREPSLPRITAPSLTEAMGPDVEVTAIERVSPTTSVFVELGEEEAEAEPADLEQVGGPVLEPPAPLTSQEGVDGRGRGLRAGPPVASDQKAGLPYEGKSILLFGGAAAVAILAVAVGVALALRRK", "length": 461 }, "evidence": [ { "id": "A0A8V0YHC3", "url": "https://omabrowser.org/oma/group/A0A8V0YHC3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "D3ZT71-1", "protein_name": "Bcl2-like 13", "gene_name": "Bcl2l13", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASSSSSTTVPLGFHYETKYVVLSYLGLLSQEKQQGPSPQGSQLDVAPQSLNPEVLLKIKSEIEEELKSLDKEVSEAFTSTGFDCHTSPVFSPANPESSVEDCLAQLGERVSRDLSEPLQKALQMILSQPVTYEAYRECTVETAVHASGWNKILVPLVLLQQMLLELARRGQEPLSTLLQFGVMYLEEHGAEFIIQQGGWGTVFSLESEEEEFPGIIAEDSNDIYILPSDNSGQVSPPESPTVTTSWQSESLPVSLSASQSWHTESLPVSLGPESWQQIAMDPEEVKSLDSSGAGEKSENNSSNSDIVHVEKEEVPEEAFPGATGPLLPQVTPMEASEMMRVEKTSPTPSVFVELGEEDLEVVTVRPDAVEGAAQLSEERSGRRRKSHTGEAIAARGTKSGLPAEGKAVLLFGGAAAVALLAVAVGVALALRKK", "length": 434 }, "evidence": [ { "id": "A0A8V0YHC3", "url": "https://omabrowser.org/oma/group/A0A8V0YHC3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3HQ88-1", "protein_name": "Bcl-2-like protein 13 isoform X1", "gene_name": "Bcl2l13", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MASSTTVPLGFHYETKYVVLSYLGLLSQGKQEGPSSQGVQLDVPPQSLDPEVLLKVKSEIEEELKSLDKEVSEAFTSTGFDCHTSPVFSPANPESSIEDCLAHLGERVSRDLKEPLNKALQVILSQPVTYQAYRECTVETAVHASGWNKILVPLVLLQQMLLELTRRGQEPLSTLLQFGVTYLEDHAAEFIIQQGGWGTVFSLESEEEEYPGIIAEDSNDIYILPSDNSGQVSPPESPTVTTSWQSESLPVSLSASQSWHTESLPVSLGPESWQQIAMDPEEVKSLDSSGAGEKSENNSSNSDIVHVEKEEVPEEAFPGAAAPLLPQTTAKEATEMRVEKGSPTPSVFAEFGEEELEAAAVRPAALEGAEQAVQLSAEGAGSRKESHTGEPTTAGAAKGAMPSEGKAVLLFGGAAAVAILAVAVGVALALRKK", "length": 433 }, "evidence": [ { "id": "A0A8V0YHC3", "url": "https://omabrowser.org/oma/group/A0A8V0YHC3/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P59017-1", "protein_name": "Bcl-2-like protein 13", "gene_name": "Bcl2l13", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASSTTASLGFHYETKYVVLSYLGLLSQEKQQGPSPPGVQLDVAPQSLNPEVLLKLKSEIEEELKTLDKEVSEAFTSTGFDCHTSPVFSPANPESSIEDCLAHLGERVSQDLKEPLQKALQTILSQPVTYEAYRECTVETAVHASGWNKLLVPLVLLQHLLLELTRRGQEPLRMLLQFGVMYLEEHAAEFIIQQGGWGSVFSLEPEEEEYPGIIAEDSNDIYILPSDNSGQVSPPESPTVTTSWQSESLPVSLSASQSWHTESLPVSLGPESWQQIAMDPEEVKSLDSSGAGEKSENNSSNSDIVHVEKEEVPEEAFPGAAAPLLTQVPTVEAPEMMRAEKTSPTPSVFVELGEEELEAVTARPEAVERAEGAAQLSEERAGSRKKSHTGEAAAVRGAKSGLPAEGKAVLLFGGAAAVAILAVAVGVALALRRK", "length": 434 }, "evidence": [ { "id": "A0A8V0YHC3", "url": "https://omabrowser.org/oma/group/A0A8V0YHC3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9BXK5-1", "protein_name": "Bcl-2-like protein 13", "gene_name": "BCL2L13", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MASSSTVPLGFHYETKYVVLSYLGLLSQEKLQEQHLSSPQGVQLDIASQSLDQEILLKVKTEIEEELKSLDKEISEAFTSTGFDRHTSPVFSPANPESSMEDCLAHLGEKVSQELKEPLHKALQMLLSQPVTYQAFRECTLETTVHASGWNKILVPLVLLRQMLLELTRRGQEPLSALLQFGVTYLEDYSAEYIIQQGGWGTVFSLESEEEEYPGITAEDSNDIYILPSDNSGQVSPPESPTVTTSWQSESLPVSLSASQSWHTESLPVSLGPESWQQIAMDPEEVKSLDSNGAGEKSENNSSNSDIVHVEKEEVPEGMEEAAVASVVLPARELQEALPEAPAPLLPHITATSLLGTREPDTEVITVEKSSPATSLFVELDEEEVKAATTEPTEVEEVVPALEPTETLLSEKEINAREESLVEELSPASEKKPVPPSEGKSRLSPAGEMKPMPLSEGKSILLFGGAAAVAILAVAIGVALALRKK", "length": 485 }, "evidence": [ { "id": "A0A8V0YHC3", "url": "https://omabrowser.org/oma/group/A0A8V0YHC3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "apoptotic process", "id": "GO:0006915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006915", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHC3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHC3" } ], "pmid": "" }, { "name": "regulation of apoptotic process", "id": "GO:0042981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042981", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHC3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHC3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHC3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHC3" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHC3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHC3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 336, "end_pos": 338, "annotation": "n_glycosylation_sequon" }, { "start_pos": 337, "end_pos": 339, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YHC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHC3" }, { "id": "PF00452", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00452" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Bcl-2 Bcl-2 homology region 1-3", "eco_id": "ECO_0000259", "start_pos": 139, "end_pos": 235, "start_aa": "Leu", "end_aa": "Trp", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 336, "end_pos": 338 }, { "start_pos": 337, "end_pos": 339 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YFL5-1", "uniprot_ac": "A0A8V0YFL5", "uniprot_id": "A0A8V0YFL5_CHICK", "mass": { "chemical_mass": 499081.0, "monoisotopic_mass": 499081.0 }, "refseq": { "ac": "XP_046792425", "name": "cardiomyopathy-associated protein 5", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046792425" }, "gene_names": [ { "name": "CMYA5", "type": "recommended", "evidence": [ { "id": "A0A8V0YFL5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFL5" } ] }, { "name": "CMYA5", "type": "synonym", "evidence": [ { "id": "XP_046792425", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046792425" } ] } ], "protein_names": [ { "name": "Cardiomyopathy associated 5", "type": "synonym", "evidence": [ { "id": "A0A8V0YFL5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFL5/entry#names_and_taxonomy" } ] }, { "name": "cardiomyopathy-associated protein 5", "type": "synonym", "evidence": [ { "id": "XP_046792425", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046792425" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_059536) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_046792425", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046792425" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFL5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFL5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CMYA5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFL5", "locus": {} } ], "crossref": [ { "id": "cd00063", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00063", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "427177", "url": "https://www.ncbi.nlm.nih.gov/gene/427177", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001870", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001870", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003877", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003877", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003879", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003879", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003961", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003961", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013320", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013320", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036116", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036116", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043136", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043136", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050617", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050617", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:427177", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427177", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "APLEMEM", "url": "https://omabrowser.org/oma/group/APLEMEM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y9B6", "url": "https://www.orthodb.org/?gene=A0A8V0Y9B6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YEF8", "url": "https://www.orthodb.org/?gene=A0A8V0YEF8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YFK9", "url": "https://www.orthodb.org/?gene=A0A8V0YFK9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YFL5", "url": "https://www.orthodb.org/?gene=A0A8V0YFL5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YHP6", "url": "https://www.orthodb.org/?gene=A0A8V0YHP6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24099", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24099", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24099:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24099:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00622", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00622", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_046792425", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046792425", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Y9B6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9B6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y9B6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9B6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YEF8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEF8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YEF8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEF8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YFK9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFK9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YFK9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFK9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YFL5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFL5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YFL5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFL5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHP6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHP6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHP6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHP6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEGYRGAECDRASETSSFIEDEEEEEEEEEEEEEEEEEAVDPEEAEELTHSLKDLIQSEDVKPKLQYIMTNPSFSMVTVQSEDSGITWETSSSRCSTPWTSETSTTSDLYSMESSPVGSPPGKVIFIMDEGKIVRKRKRKPSNRMPLPTHVIGGQGNKKRDFSGMQRQEPRTVLGDVHGSVLNVEQMEAQDIDEDMLEDREDLENIAEQPVKRAPIRSIFRESRLRKVGPILGGPVKSRIQLFNSIFGGTGPLPETLEKGRIQRKSSVSGELECFLEASVKERSHKFISETTHTKSFQRTSRSFETPSERRRNQRQQSTAQSNQSYSSVTPLEKQLSSKDVAFKNIKPVKTKDKPSKFSKSGEETTFQHEERKDRQSQLENLNQVSGKSQKFSPPKEARKQQSYSYLPAANSAITEELTTTALESDDKSEEQVPLPSKETANKKPDKSLLTASDLLDEPKEQEIQPSSTLPSVLADSVNKLDRQSTQPTVSAAEHLEKEVQKSAVQSYLPYAPSAKSSYSTPSETRQEDIIPKSSETAQSESGHVLLPHSLDVTEKQETECHLSATAQSETDHSGLLYSVKKKESQRTPLPEIQNICLEKQTKSEQDLFFAQEAEEQVIKLNSHTPEKMDSKYFGISYPVCTETQETRKKSVVNKALDLDRPVFSVDKNNQAESAQMEMEYPDFSYSNEESGESEILQTETEHPDFSFSKEVTGQFESAQLKTDNPHFPYSTEETDKSKSSQGETEQPDFSFSREEVRESESAQLETVNPEFLFSKKEIEKSESPHLETEHPDFSYSREEMMESKSAQLEMEQSDFSFSREEIEDSESAQPKIEHPDFSYFREEMVESDDAHMKMEQPDFSFSREEIEDSESAQPKIEHPDFSYSREEMVESDYAHMKMEQPDISLTREETRELESTQLETKHPEFDFSKEDMQESESTQMETEHPDFSYSREKMVKTESAQLEQTDFSFSREETEESESAQLETKHRDFLFSREETEGQKSIPFELEQPKSYSPEEAEHERTAQLELEPSDISCSMEEAEKENTTELELVHPDISDFAGRDRMQHMGHKETRHSDLPYPMDETKHQDLAQVDNNKPLLSYFDDRGEQPQPVQKDLQPGGKLYSLGNSMQGETNQLHSECPVLPYSAAKEQQHKEESDTSYLTGKTDQEIFQSKVEHADFPYFCGEAAQEAVQKDVGSPEWSSFTSETQQSEITQLASENRDLSFTTGEIVQEEMKSGSSYSSHSIDRPTHRQMVQLEQEHLLPTYSSPDSQQEETTPLDLPQPDISYSTGKVKQENRVQRGQEEMVEIQSEATQKELDYSDLTENWGKAETRDMDQMNLAQQETTEPELEHPPLPYSFSELMQEEKEVESAYPEQTFYASIDMKEKVTQQKTKQPFLSCFTGKKEDEIMHPEQEQTSVPFSSGKEAPLEMEMGSEYPDVSYSSHRPEQEKFRHPTLPFSSKEQEAAPPVIEHPDFSYNTGELKPGDTIQQESEYPEKSYSMEEMQQESEYLDSPETLGRAQDETVEMESEYPDVSCSDDQKSQQETSQLASKYPGTLFSFSDFKEQATQEFDSKHKDLPRVARKRALPETAQIDSKYPDLTYSFGKAEEPEISQSEARHSDLSHSTGETNKSDLLDQKHIKISVDREKQQQTPEEQVEQEKFSYSSSKTEQLKYAEEGFEKQDLSFSSVRPDEKMALTETEHAAVINPLEKAEVQQRVQLESEQMDLTRPFEKEEQKMAQPEAERSRLAHSVGTAELEEIAEPAQRYPDLPYSVFKVGKLQSEELKPEHPGLACSFNKVKEITQLNVLDTHDKTEECPLAKLELGNEDLASPADKIGQQGMVHTALECPDENQSASRAQHPQPTKEKLEVPDISSHSGNEEQRGMAKPVLKHPDLSYSTHGTQPQKNTQLELGKPDLATWPGKTEQAQPAQKEQSGFLHSFYKEEAQPEMGRSQVSYSVSETEQEIAHEESIHSDLSAGRLKQHEFIQPEAEIMDLSCLVGEPQQSQIDELDLEYPDLSHSTGALQKQEEVQPELEEPSDFSSSLRKEQGENARMQAECSEFQSSVWKAERLQDSQVESERTDLSFSVTIAESHETTPSVLKELDLLRSSVKTMQSWDSPEPDHLNISNAVAKVPHPDMFSSTSEEKQSAQVDFKQERESCALHTEEMTKLKLEQPTLSSAHGTVEQPRRTSMEGEFLDTSRLSGEKRENRKEKRDMSRQELEHLSDLSDLTDKTQQQETTQPESRQSDLSSYSGKKEQPQTVQVEGEHQELLRFPGETQRQGTAEPEVEHSDLSYSIGKVEQPQATQWKSEQPVAPHHIGTTDQQGIAHSVQDLGQDFIYDPGKTDEIQTVQGELEHTALLYSSDKTEQEMVMSELQHPQLSYSVRVIEEKTAHQKSDNKDLSYSTCHQEHHKTVQPEMEEMDLSYPTEKSEHSQSAQIVLQKPGFLKSFGKLEEKGLAQPSFLHSVGEEKQKPSSELDLMQPCLSHLLDKAEKQETAQEVFMSSDFSYSMGKADQLQTEQVKLKYPDFSYSLDKAETHGVKPLGLLSSYSKAEQTQTAHPEHPETSYVAGRTEKKDGIHPELQCFNLPSSAVEVEQQETFSVSYTSARTEEQQTAELKSEQSDLLNSTEKVEKGEIAESRAGHSEKWNTGIISSLTTLLETEQDLSFSTKEATSQKTQPFSSLPEKSVSVPLGVSHSETKVERNPKSSPVTGSLSSEHLDLSYSRCKTEPSETAQPVSGFFSTRKEAENTRIHLHLPMSAQSEAEHVILPETEREQTPHYFHTTPQLESEKLSTTYCIDKAETLEGQEYLTAPSKLETESSAPFYSVDETHQQEILPYSKPASENLFAEYSLAEQEKQSMKLVIPQSAQSECKHVTPPHDEAELQKNQVYSPKPASLKTEQFENKTIVHRKERDEQDLTECLSLEQLSSPKLSVKWDKQEVQPDVQKVPQLVSAESKATAVADQQSVSSDPFVPFHAVSEKTVSVSFTDDKEKQNIPSSLPNILGIPENQTNIVSGSYTKEEDRHGMQPYFTGQKHSSLEQPRSVSSDLVCDTVAHKTRHYSCEQGTLYSMESKPIFPSSNEKQNPDIPSPGLASWLAEEVKAHSINPIPAKGVDKLSPNEASDLGSKQFPAGNFTEVAVHGTTDNKGDTFRVSDSETEISCGLSSEAGHRAGRHDLPSPRADNPGSDKGPESETRFGNPTKRKAAQHLEEDKMSEVSEHYLRREEEEMKHMSTVEDSQHAPEPIEQKDLFNIISEGYEILNIHAPTHISSIDQEESKHMPDKLEYLETNPSFKKKIAHERHEASASETTEISGISVLGMSESHEVKELVKTEDAGETEEIQEENPVLSESKNHAVLDPDNGISEIDYFEKYTLIDDKSPIKPHFERPSSSFPVKEDLNEPVEQATSSKETAEEDTLEEEFALLEDLDEVFYGTVKGESKMESYAGASEPFPLQKSIDISSKKTTSVEDEQKSPGTPLFDSEEGVLERSLLFPTTVAAVNPELLEEPPALSFLYKDLYAEAVGEKTKDETPSDEESGNSNASFPSRNSDTDDGTGIYFEKYILKDEIPGKVLEPQKDQIPEDESFSGGISVPSSEEKYKQTSADALSVRTETVPEREIVEKVHSDIKATICKPTHAIPFGGRVIVSGARSDVTEQREENVPVETTEELPEQTSQQGYSQIVDSLGAAHRESINKQEEHREITAAPQVEQYVPYNRTPVEDSEDDQYTQEIVSHVPTIQQREKPDFQREEQHPHVYEDFAESMDYDVITQEELLQDEISSELTHEELLFEDRDSFEHIGDSYEFFNEPEQRTPVELEDSGFVVMYPEKSAANIPEIESPQRELKKAQTDTYCYHCKCPISAIDKLFGEHKDHEVTTLDDAATKMKDHLGELLIALEKKSMKIEEFVSDIESLFNSVEENCKKNAELLEKQNEEMLKKMVAQYDEKSENFEEVKRMKMEYLYEQMVNFQQTVDSAKETLETTVKEMEELNGFAFLNSSKELNKRLCSAMDATLSLEKVPSTFSLFEHYVDSPGKSNQNSLKHVAVPQTPTLIPQEPNSATSTSIAVYWTVNEGDAIDCFQVYCMEELQASKDEGALVEEYRVTVKESHCILEDLEPDRCYSVWVMAVNCTGCSLPSEKSIFKTAPAIPTIKAEDCTVCWDTATIRWQVASAAAESFTLEYCRQHSPEGEGLRSFAGIKRHELKVSLEPNVNYFFYLRAVNTFGTSEQSEAALISTKGTRFHILSDTAHPALQISPDETIICLPEKATFTGFPSVLGELLPARGCHYWETVVTACRSYRIGICYETTPQSSDVGLSDTSWCMHCCPTQTSFLYRFFHMDVMSDVHVTEQLARIGILLDYNGGRLLFFNAERGLVLFTIRHKFTDAVYPAFALDKAGMLTLHTGMDLPEFVKHS", "length": 4413, "header": "tr|A0A8V0YFL5-1|A0A8V0YFL5_CHICK Isoform 1 of Cardiomyopathy associated 5 OS=Gallus gallus OX=9031 GN=CMYA5 PE=4 SV=1 CANONICAL=A0A8V0YFL5-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Y9B6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFL5/entry#A0A8V0Y9B6-1", "sequence": { "sequence": "MEGYRGAECDRASETSSFIEDEEEEEEEEEEEEEEEEEAVDPEEAEELTHSLKDLIQSEDVKPKLQYIMTNPSFSMVTVQSEDSGITWETSSSRCSTPWTSETSTTSDLYSMESSPVGSPPGKVIFIMDEGKIVRKRKRKPSNRMPLPTHVIGGQGNKKRDFSGMQRQEPRTVLGDVHGSVLNVEQMEAQDIDEDMLEDREDLENIAEQPVKRAPIRSIFRESRLRKVGPILGGPVKSRIQLFNSIFGGTGPLPETLEKGRIQRKSSVSGELECFLEASVKERSHKFISETTHTKSFQRTSRSFETPSERRRNQRQQSTAQSNQSYSSVTPLEKQLSSKDVAFKNIKPVKTKDKPSKFSKSGEETTFQHEERKDRQSQLENLNQVSGKSQKFSPPKEARKQQSYSYLPAANSAITEELTTTALESDDKSEEQVPLPSKETANKKPDKSLLTASDLLDEPKEQEIQPSSTLPSVLADSVNKLDRQSTQPTVSAAEHLEKEVQKSAVQSYLPYAPSAKSSYSTPSETRQEDIIPKSSETAQSESGHVLLPHSLDVTEKQETECHLSATAQSETDHSGLLYSVKKKESQRTPLPEIQNICLEKQTKSEQDLFFAQEAEEQVIKLNSHTPEKMDSKYFGISYPVCTETQETRKKSVVNKALDLDRPVFSVDKNNQAESAQMEMEYPDFSYSNEESGESEILQTETEHPDFSFSKEVTGQFESAQLKTDNPHFPYSTEETDKSKSSQGETEQPDFSFSREEVRESESAQLETVNPEFLFSKKEIEKSESPHLETEHPDFSYSREEMMESKSAQLEMEQSDFSFSREEIEDSESAQPKIEHPDFSYFREEMVESDDAHMKMEQPDFSFSREEIEDSESAQPKIEHPDFSYSREEMVESDYAHMKMEQPDISLTREETRELESTQLETKHPEFDFSKEDMQESESTQMETEHPDFSYSREKMVKTESAQLEQTDFSFSREETEESESAQLETKHRDFLFSREETEGQKSIPFELEQPKSYSPEEAEHERTAQLELEPSDISCSMEEAEKENTTELELVHPDISDFAGRDRMQHMGHKETRHSDLPYPMDETKHQDLAQVDNNKPLLSYFDDRGEQPQPVQKDLQPGGKLYSLGNSMQGETNQLHSECPVLPYSAAKEQQHKEESDTSYLTGKTDQEIFQSKVEHADFPYFCGEAAQEAVQKDVGSPEWSSFTSETQQSEITQLASENRDLSFTTGEIVQEEMKSGSSYSSHSIDRPTHRQMVQLEQEHLLPTYSSPDSQQEETTPLDLPQPDISYSTGKVKQENRVQRGQEEMVEIQSEATQKELDYSDLTENWGKAETRDMDQMNLAQQETTEPELEHPPLPYSFSELMQEEKEVESAYPEQTFYASIDMKEKVTQQKTKQPFLSCFTGKKEDEIMHPEQEQTSVPFSSGKEAPLEMEMGSEYPDVSYSSHRPEQEKFRHPTLPFSSKEQEAAPPVIEHPDFSYNTGELKPGDTIQQESEYPEKSYSMEEMQQESEYLDSPETLGRAQDETVEMESEYPDVSCSDDQKSQQETSQLASKYPGTLFSFSDFKEQATQEFDSKHKDLPRVARKRALPETAQIDSKYPDLTYSFGKAEEPEISQSEARHSDLSHSTGETNKSDLLDQKHIKISVDREKQQQTPEEQVEQEKFSYSSSKTEQLKYAEEGFEKQDLSFSSVRPDEKMALTETEHAAVINPLEKAEVQQRVQLESEQMDLTRPFEKEEQKMAQPEAERSRLAHSVGTAELEEIAEPAQRYPDLPYSVFKVGKLQSEELKPEHPGLACSFNKVKEITQLNVLDTHDKTEECPLAKLELGNEDLASPADKIGQQGMVHTALECPDENQSASRAQHPQPTKEKLEVPDISSHSGNEEQRGMAKPVLKHPDLSYSTHGTQPQKNTQLELGKPDLATWPGKTEQAQPAQKEQSGFLHSFYKEEAQPEMGRSQVSYSVSETEQEIAHEESIHSDLSAGRLKQHEFIQPEAEIMDLSCLVGEPQQSQIDELDLEYPDLSHSTGALQKQEEVQPELEEPSDFSSSLRKEQGENARMQAECSEFQSSVWKAERLQDSQVESERTDLSFSVTIAESHETTPSVLKELDLLRSSVKTMQSWDSPEPDHLNISNAVAKVPHPDMFSSTSEEKQSAQVDFKQERESCALHTEEMTKLKLEQPTLSSAHGTVEQPRRTSMEGEFLDTSRLSGEKRENRKEKRDMSRQELEHLSDLSDLTDKTQQQETTQPESRQSDLSSYSGKKEQPQTVQVEGEHQELLRFPGETQRQGTAEPEVEHSDLSYSIGKVEQPQATQWKSEQPVAPHHIGTTDQQGIAHSVQDLGQDFIYDPGKTDEIQTVQGELEHTALLYSSDKTEQEMVMSELQHPQLSYSVRVIEEKTAHQKSDNKDLSYSTCHQEHHKTVQPEMEEMDLSYPTEKSEHSQSAQIVLQKPGFLKSFGKLEEKGLAQPSFLHSVGEEKQKPSSELDLMQPCLSHLLDKAEKQETAQEVFMSSDFSYSMGKADQLQTEQVKLKYPDFSYSLDKAETHGVKPLGLLSSYSKAEQTQTAHPEHPETSYVAGRTEKKDGIHPELQCFNLPSSAVEVEQQETFSVSYTSARTEEQQTAELKSEQSDLLNSTEKVEKGEIAESRAGHSEKWNTGIISSLTTLLETEQDLSFSTKEATSQKTQPFSSLPEKSVSVPLGVSHSETKVERNPKSSPVTGSLSSEHLDLSYSRCKTEPSETAQPVSGFFSTRKEAENTRIHLHLPMSAQSEAEHVILPETEREQTPHYFHTTPQLESEKLSTTYCIDKAETLEGQEYLTAPSKLETESSAPFYSVDETHQQEILPYSKPASENLFAEYSLAEQEKQSMKLVIPQSAQSECKHVTPPHDEAELQKNQVYSPKPASLKTEQFENKTIVHRKERDEQDLTECLSLEQLSSPKLSVKWDKQEVQPDVQKVPQLVSAESKATAVADQQSVSSDPFVPFHAVSEKTVSVSFTDDKEKQNIPSSLPNILGIPENQTNIVSGSYTKEEDRHGMQPYFTGQKHSSLEQPRSVSSDLVCDTVAHKTRHYSCEQGTLYSMESKPIFPSSNEKQNPDIPSPGLASWLAEEVKAHSINPIPAKGVDKLSPNEASDLGSKQFPAGNFTEVAVHGTTDNKGDTFRVSDSETEISCGLSSEAGHRAGRHDLPSPRADNPGSDKGPESETRFGNPTKRKAAQHLEEDKMSEVSEHYLRREEEEMKHMSTVEDSQHAPEPIEQKDLFNIISEGYEILNIHAPTHISSIDQEESKHMPDKLEYLETNPSFKKKIAHERHEASASETTEISGISVLGMSESHEVKELVKTEDAGETEEIQEENPVLSESKNHAVLDPDNGISEIDYFEKYTLIDDKSPIKPHFERPSSSFPVKEDLNEPVEQATSSKETAEEDTLEEEFALLEDLDEVFYGTVKGESKMESYAGASEPFPLQKSIDISSKKTTSVEDEQKSPGTPLFDSEEGVLERSLLFPTTVAAVNPELLEEPPALSFLYKDLYAEAVGEKTKDETPSDEESGNSNASFPSRNSDTDDGTGIYFEKYILKDEIPGKVLEPQKDQIPEDESFSGGISVPSSEEKYKQTSADALSVRTETVPEREIVEKVHSDIKATICKPTHAIPFGGRVIVSGARSDVTEQREENVPVETTEELPEQTSQQGYSQIVDSLGAAHRESINKQEEHREITAAPQVEQYVPYNRTPVEDSEDDQYTQEIVSHVPTIQQREKPDFQREEQHPHVYEDFAESMDYDVITQEELLQDEISSELTHEELLFEDRDSFEHIGDSYEFFNEPEQRTPVELEDSGFVVMYPEKSAANIPEIESPQRELKKAQTDTYCYHCKCPISAIDKLFGEHKDHEVTTLDDAATKMKDHLGELLIALEKKSMKIEEFVSDIESLFNSVEENCKKNAELLEKQNEEMLKKMVAQYDEKSENFEEVKRMKMEYLYEQMVNFQQTVDSAKETLETTVKEMEELNGFAFLNSHRHQP", "length": 4003, "header": "tr|A0A8V0Y9B6-1|A0A8V0Y9B6_CHICK Computationally mapped isoform of Cardiomyopathy associated 5 OS=Gallus gallus OX=9031 GN=CMYA5 PE=4 SV=1 CANONICAL=A0A8V0YFL5-1" }, "locus": { "chromosome": "Z", "start_pos": 22713878, "end_pos": 22683486, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029731.1", "url": "https://www.ensembl.org/id/ENSGALT00010029731.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017307.1", "url": "https://www.ensembl.org/id/ENSGALP00010017307.1" } ] } }, { "isoform_ac": "A0A8V0YEF8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFL5/entry#A0A8V0YEF8-1", "sequence": { "sequence": "MEGYRGAECDRASETSSFIEDEEEEEEEEEEEEEEEEEAVDPEEAEELTHSLKDLIQSEDVKPKLQYIMTNPSFSMVTVQSEDSGITWETSSSRCSTPWTSETSTTSDLYSMESSPVGSPPGKVIFIMDEGKIVRKRKRKPSNRMPLPTHVIGGQGNKKRDFSGMQRQEPRTVLGDVHGSVLNVEQMEAQDIDEDMLEDREDLENIAEQPVKRAPIRSIFRESRLRKVGPILGGPVKSRIQLFNSIFGGTGPLPETLEKGRIQRKSSVSGELECFLEASVKERSHKFISETTHTKSFQRTSRSFETPSERRRNQRQQSTAQSNQSYSSVTPLEKQLSSKDVAFKNIKPVKTKDKPSKFSKSGEETTFQHEERKDRQSQLENLNQVSGKSQKFSPPKEARKQQSYSYLPAANSAITEELTTTALESDDKSEEQVPLPSKETANKKPDKSLLTASDLLDEPKEQEIQPSSTLPSVLADSVNKLDRQSTQPTVSAAEHLEKEVQKSAVQSYLPYAPSAKSSYSTPSETRQEDIIPKSSETAQSESGHVLLPHSLDVTEKQETECHLSATAQSETDHSGLLYSVKKKESQRTPLPEIQNICLEKQTKSEQDLFFAQEAEEQVIKLNSHTPEKMDSKYFGISYPVCTETQETRKKSVVNKALDLDRPVFSVDKNNQAESAQMEMEYPDFSYSNEESGESEILQTETEHPDFSFSKEVTGQFESAQLKTDNPHFPYSTEETDKSKSSQGETEQPDFSFSREEVRESESAQLETVNPEFLFSKKEIEKSESPHLETEHPDFSYSREEMMESKSAQLEMEQSDFSFSREEIEDSESAQPKIEHPDFSYFREEMVESDDAHMKMEQPDFSFSREEIEDSESAQPKIEHPDFSYSREEMVESDYAHMKMEQPDISLTREETRELESTQLETKHPEFDFSKEDMQESESTQMETEHPDFSYSREKMVKTESAQLEQTDFSFSREETEESESAQLETKHRDFLFSREETEGQKSIPFELEQPKSYSPEEAEHERTAQLELEPSDISCSMEEAEKENTTELELVHPDISDFAGRDRMQHMGHKETRHSDLPYPMDETKHQDLAQVDNNKPLLSYFDDRGEQPQPVQKDLQPGGKLYSLGNSMQGETNQLHSECPVLPYSAAKEQQHKEESDTSYLTGKTDQEIFQSKVEHADFPYFCGEAAQEAVQKDVGSPEWSSFTSETQQSEITQLASENRDLSFTTGEIVQEEMKSGSSYSSHSIDRPTHRQMVQLEQEHLLPTYSSPDSQQEETTPLDLPQPDISYSTGKVKQENRVQRGQEEMVEIQSEATQKELDYSDLTENWGKAETRDMDQMNLAQQETTEPELEHPPLPYSFSELMQEEKEVESAYPEQTFYASIDMKEKVTQQKTKQPFLSCFTGKKEDEIMHPEQEQTSVPFSSGKEAPLEMEMGSEYPDVSYSSHRPEQEKFRHPTLPFSSKEQEAAPPVIEHPDFSYNTGELKPGDTIQQESEYPEKSYSMEEMQQESEYLDSPETLGRAQDETVEMESEYPDVSCSDDQKSQQETSQLASKYPGTLFSFSDFKEQATQEFDSKHKDLPRVARKRALPETAQIDSKYPDLTYSFGKAEEPEISQSEARHSDLSHSTGETNKSDLLDQKHIKISVDREKQQQTPEEQVEQEKFSYSSSKTEQLKYAEEGFEKQDLSFSSVRPDEKMALTETEHAAVINPLEKAEVQQRVQLESEQMDLTRPFEKEEQKMAQPEAERSRLAHSVGTAELEEIAEPAQRYPDLPYSVFKVGKLQSEELKPEHPGLACSFNKVKEITQLNVLDTHDKTEECPLAKLELGNEDLASPADKIGQQGMVHTALECPDENQSASRAQHPQPTKEKLEVPDISSHSGNEEQRGMAKPVLKHPDLSYSTHGTQPQKNTQLELGKPDLATWPGKTEQAQPAQKEQSGFLHSFYKEEAQPEMGRSQVSYSVSETEQEIAHEESIHSDLSAGRLKQHEFIQPEAEIMDLSCLVGEPQQSQIDELDLEYPDLSHSTGALQKQEEVQPELEEPSDFSSSLRKEQGENARMQAECSEFQSSVWKAERLQDSQVESERTDLSFSVTIAESHETTPSVLKELDLLRSSVKTMQSWDSPEPDHLNISNAVAKVPHPDMFSSTSEEKQSAQVDFKQERESCALHTEEMTKLKLEQPTLSSAHGTVEQPRRTSMEGEFLDTSRLSGEKRENRKEKRDMSRQELEHLSDLSDLTDKTQQQETTQPESRQSDLSSYSGKKEQPQTVQVEGEHQELLRFPGETQRQGTAEPEVEHSDLSYSIGKVEQPQATQWKSEQPVAPHHIGTTDQQGIAHSVQDLGQDFIYDPGKTDEIQTVQGELEHTALLYSSDKTEQEMVMSELQHPQLSYSVRVIEEKTAHQKSDNKDLSYSTCHQEHHKTVQPEMEEMDLSYPTEKSEHSQSAQIVLQKPGFLKSFGKLEEKGLAQPSFLHSVGEEKQKPSSELDLMQPCLSHLLDKAEKQETAQEVFMSSDFSYSMGKADQLQTEQVKLKYPDFSYSLDKAETHGVKPLGLLSSYSKAEQTQTAHPEHPETSYVAGRTEKKDGIHPELQCFNLPSSAVEVEQQETFSVSYTSARTEEQQTAELKSEQSDLLNSTEKVEKGEIAESRAGHSEKWNTGIISSLTTLLETEQDLSFSTKEATSQKTQPFSSLPEKSVSVPLGVSHSETKVERNPKSSPVTGSLSSEHLDLSYSRCKTEPSETAQPVSGFFSTRKEAENTRIHLHLPMSAQSEAEHVILPETEREQTPHYFHTTPQLESEKLSTTYCIDKAETLEGQEYLTAPSKLETESSAPFYSVDETHQQEILPYSKPASENLFAEYSLAEQEKQSMKLVIPQSAQSECKHVTPPHDEAELQKNQVYSPKPASLKTEQFENKTIVHRKERDEQDLTECLSLEQLSSPKLSVKWDKQEVQPDVQKVPQLVSAESKPIFPSSNEKQNPDIPSPGLASWLAEEVKAHSINPIPAKGVDKLSPNEASDLGSKQFPAGNFTEVAVHGTTDNKGDTFRVSDSETEISCGLSSEAGHRAGRHDLPSPRADNPGSDKGPESETRFGNPTKRKAAQHLEEDKMSEVSEHYLRREEEEMKHMSTVEDSQHAPEPIEQKDLFNIISEGYEILNIHAPTHISSIDQEESKHMPDKLEYLETNPSFKKKIAHERHEASASETTEISGISVLGMSESHEVKELVKTEDAGETEEIQEENPVLSESKNHAVLDPDNGISEIDYFEKYTLIDDKSPIKPHFERPSSSFPVKEDLNEPVEQATSSKETAEEDTLEEEFALLEDLDEVFYGTVKGESKMESYAGASEPFPLQKSIDISSKKTTSVEDEQKSPGTPLFDSEEGVLERSLLFPTTVAAVNPELLEEPPALSFLYKDLYAEAVGEKTKDETPSDEESGNSNASFPSRNSDTDDGTGIYFEKYILKDEIPGKVLEPQKDQIPEDESFSGGISVPSSEEKYKQTSADALSVRTETVPEREIVEKVHSDIKATICKPTHAIPFGGRVIVSGARSDVTEQREENVPVETTEELPEQTSQQGYSQIVDSLGAAHRESINKQEEHREITAAPQVEQYVPYNRTPVEDSEDDQYTQEIVSHVPTIQQREKPDFQREEQHPHVYEDFAESMDYDVITQEELLQDEISSELTHEELLFEDRDSFEHIGDSYEFFNEPEQRTPVELEDSGFVVMYPEKSAANIPEIESPQRELKKAQTDTYCYHCKCPISAIDKLFGEHKDHEVTTLDDAATKMKDHLGELLIALEKKSMKIEEFVSDIESLFNSVEENCKKNAELLEKQNEEMLKKMVAQYDEKSENFEEVKRMKMEYLYEQMVNFQQTVDSAKETLETTVKEMEELNGFAFLNSSKELNKRLCSAMDATLSLEKVPSTFSLFEHYVDSPGKSNQNSLKHVAVPQTPTLIPQEPNSATSTSIAVYWTVNEGDAIDCFQVYCMEELQASKDEGALVEEYRVTVKESHCILEDLEPDRCYSVWVMAVNCTGCSLPSEKSIFKTAPAIPTIKAEDCTVCWDTATIRWQVASAAAESFTLEYCRQHSPEGEGLRSFAGIKRHELKVSLEPNVNYFFYLRAVNTFGTSEQSEAALISTKGTRFHILSDTAHPALQISPDETIICLPEKATFTGFPSVLGELLPARGCHYWETVVTACRSYRIGICYETTPQSSDVGLSDTSWCMHCCPTQTSFLYRFFHMDVMSDVHVTEQLARIGILLDYNGGRLLFFNAERGLVLFTIRHKFTDAVYPAFALDKAGMLTLHTGMDLPEFVKHS", "length": 4296, "header": "tr|A0A8V0YEF8-1|A0A8V0YFL5_CHICK Computationally mapped isoform of Cardiomyopathy associated 5 OS=Gallus gallus OX=9031 GN=CMYA5 PE=4 SV=1 CANONICAL=A0A8V0YFL5-1" }, "locus": { "chromosome": "Z", "start_pos": 22713878, "end_pos": 22666593, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029735.1", "url": "https://www.ensembl.org/id/ENSGALT00010029735.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017311.1", "url": "https://www.ensembl.org/id/ENSGALP00010017311.1" } ] } }, { "isoform_ac": "A0A8V0YFK9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFL5/entry#A0A8V0YFK9-1", "sequence": { "sequence": "MVESDDAHMKMEQPDFSFSREEIEDSESAQPKIEHPDFSYSREEMVESDYAHMKMEQPDISLTREETRELESTQLETKHPEFDFSKEDMQESESTQMETEHPDFSYSREKMVKTESAQLEQTDFSFSREETEESESAQLETKHRDFLFSREETEGQKSIPFELEQPKSYSPEEAEHERTAQLELEPSDISCSMEEAEKENTTELELVHPDISDFAGRDRMQHMGHKETRHSDLPYPMDETKHQDLAQVDNNKPLLSYFDDRGEQPQPVQKDLQPGGKLYSLGNSMQGETNQLHSECPVLPYSAAKEQQHKEESDTSYLTGKTDQEIFQSKVEHADFPYFCGEAAQEAVQKDVGSPEWSSFTSETQQSEITQLASENRDLSFTTGEIVQEEMKSGSSYSSHSIDRPTHRQMVQLEQEHLLPTYSSPDSQQEETTPLDLPQPDISYSTGKVKQENRVQRGQEEMVEIQSEATQKELDYSDLTENWGKAETRDMDQMNLAQQETTEPELEHPPLPYSFSELMQEEKEVESAYPEQTFYASIDMKEKVTQQKTKQPFLSCFTGKKEDEIMHPEQEQTSVPFSSGKEAPLEMEMGSEYPDVSYSSHRPEQEKFRHPTLPFSSKEQEAAPPVIEHPDFSYNTGELKPGDTIQQESEYPEKSYSMEEMQQESEYLDSPETLGRAQDETVEMESEYPDVSCSDDQKSQQETSQLASKYPGTLFSFSDFKEQATQEFDSKHKDLPRVARKRALPETAQIDSKYPDLTYSFGKAEEPEISQSEARHSDLSHSTGETNKSDLLDQKHIKISVDREKQQQTPEEQVEQEKFSYSSSKTEQLKYAEEGFEKQDLSFSSVRPDEKMALTETEHAAVINPLEKAEVQQRVQLESEQMDLTRPFEKEEQKMAQPEAERSRLAHSVGTAELEEIAEPAQRYPDLPYSVFKVGKLQSEELKPEHPGLACSFNKVKEITQLNVLDTHDKTEECPLAKLELGNEDLASPADKIGQQGMVHTALECPDENQSASRAQHPQPTKEKLEVPDISSHSGNEEQRGMAKPVLKHPDLSYSTHGTQPQKNTQLELGKPDLATWPGKTEQAQPAQKEQSGFLHSFYKEEAQPEMGRSQVSYSVSETEQEIAHEESIHSDLSAGRLKQHEFIQPEAEIMDLSCLVGEPQQSQIDELDLEYPDLSHSTGALQKQEEVQPELEEPSDFSSSLRKEQGENARMQAECSEFQSSVWKAERLQDSQVESERTDLSFSVTIAESHETTPSVLKELDLLRSSVKTMQSWDSPEPDHLNISNAVAKVPHPDMFSSTSEEKQSAQVDFKQERESCALHTEEMTKLKLEQPTLSSAHGTVEQPRRTSMEGEFLDTSRLSGEKRENRKEKRDMSRQELEHLSDLSDLTDKTQQQETTQPESRQSDLSSYSGKKEQPQTVQVEGEHQELLRFPGETQRQGTAEPEVEHSDLSYSIGKVEQPQATQWKSEQPVAPHHIGTTDQQGIAHSVQDLGQDFIYDPGKTDEIQTVQGELEHTALLYSSDKTEQEMVMSELQHPQLSYSVRVIEEKTAHQKSDNKDLSYSTCHQEHHKTVQPEMEEMDLSYPTEKSEHSQSAQIVLQKPGFLKSFGKLEEKGLAQPSFLHSVGEEKQKPSSELDLMQPCLSHLLDKAEKQETAQEVFMSSDFSYSMGKADQLQTEQVKLKYPDFSYSLDKAETHGVKPLGLLSSYSKAEQTQTAHPEHPETSYVAGRTEKKDGIHPELQCFNLPSSAVEVEQQETFSVSYTSARTEEQQTAELKSEQSDLLNSTEKVEKGEIAESRAGHSEKWNTGIISSLTTLLETEQDLSFSTKEATSQKTQPFSSLPEKSVSVPLGVSHSETKVERNPKSSPVTGSLSSEHLDLSYSRCKTEPSETAQPVSGFFSTRKEAENTRIHLHLPMSAQSEAEHVILPETEREQTPHYFHTTPQLESEKLSTTYCIDKAETLEGQEYLTAPSKLETESSAPFYSVDETHQQEILPYSKPASENLFAEYSLAEQEKQSMKLVIPQSAQSECKHVTPPHDEAELQKNQVYSPKPASLKTEQFENKTIVHRKERDEQDLTECLSLEQLSSPKLSVKWDKQEVQPDVQKVPQLVSAESKATAVADQQSVSSDPFVPFHAVSEKTVSVSFTDDKEKQNIPSSLPNILGIPENQTNIVSGSYTKEEDRHGMQPYFTGQKHSSLEQPRSVSSDLVCDTVAHKTRHYSCEQGTLYSMESKPIFPSSNEKQNPDIPSPGLASWLAEEVKAHSINPIPAKGVDKLSPNEASDLGSKQFPAGNFTEVAVHGTTDNKGDTFRVSDSETEISCGLSSEAGHRAGRHDLPSPRADNPGSDKGPESETRFGNPTKRKAAQHLEEDKMSEVSEHYLRREEEEMKHMSTVEDSQHAPEPIEQKDLFNIISEGYEILNIHAPTHISSIDQEESKHMPDKLEYLETNPSFKKKIAHERHEASASETTEISGISVLGMSESHEVKELVKTEDAGETEEIQEENPVLSESKNHAVLDPDNGISEIDYFEKYTLIDDKSPIKPHFERPSSSFPVKEDLNEPVEQATSSKETAEEDTLEEEFALLEDLDEVFYGTVKGESKMESYAGASEPFPLQKSIDISSKKTTSVEDEQKSPGTPLFDSEEGVLERSLLFPTTVAAVNPELLEEPPALSFLYKDLYAEAVGEKTKDETPSDEESGNSNASFPSRNSDTDDGTGIYFEKYILKDEIPGKVLEPQKDQIPEDESFSGGISVPSSEEKYKQTSADALSVRTETVPEREIVEKVHSDIKATICKPTHAIPFGGRVIVSGARSDVTEQREENVPVETTEELPEQTSQQGYSQIVDSLGAAHRESINKQEEHREITAAPQVEQYVPYNRTPVEDSEDDQYTQEIVSHVPTIQQREKPDFQREEQHPHVYEDFAESMDYDVITQEELLQDEISSELTHEELLFEDRDSFEHIGDSYEFFNEPEQRTPVELEDSGFVVMYPEKSAANIPEIESPQRELKKAQTDTYCYHCKCPISAIDKLFGEHKDHEVTTLDDAATKMKDHLGELLIALEKKSMKIEEFVSDIESLFNSVEENCKKNAELLEKQNEEMLKKMVAQYDEKSENFEEVKRMKMEYLYEQMVNFQQTVDSAKETLETTVKEMEELNGFAFLNKQPPLTLL", "length": 3161, "header": "tr|A0A8V0YFK9-1|A0A8V0YFK9_CHICK Computationally mapped isoform of Cardiomyopathy associated 5 OS=Gallus gallus OX=9031 GN=CMYA5 PE=4 SV=1 CANONICAL=A0A8V0YFL5-1" }, "locus": { "chromosome": "Z", "start_pos": 22704117, "end_pos": 22689458, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029728.1", "url": "https://www.ensembl.org/id/ENSGALT00010029728.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017304.1", "url": "https://www.ensembl.org/id/ENSGALP00010017304.1" } ] } }, { "isoform_ac": "A0A8V0YFL5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFL5/entry#A0A8V0YFL5-1", "sequence": { "sequence": "MEGYRGAECDRASETSSFIEDEEEEEEEEEEEEEEEEEAVDPEEAEELTHSLKDLIQSEDVKPKLQYIMTNPSFSMVTVQSEDSGITWETSSSRCSTPWTSETSTTSDLYSMESSPVGSPPGKVIFIMDEGKIVRKRKRKPSNRMPLPTHVIGGQGNKKRDFSGMQRQEPRTVLGDVHGSVLNVEQMEAQDIDEDMLEDREDLENIAEQPVKRAPIRSIFRESRLRKVGPILGGPVKSRIQLFNSIFGGTGPLPETLEKGRIQRKSSVSGELECFLEASVKERSHKFISETTHTKSFQRTSRSFETPSERRRNQRQQSTAQSNQSYSSVTPLEKQLSSKDVAFKNIKPVKTKDKPSKFSKSGEETTFQHEERKDRQSQLENLNQVSGKSQKFSPPKEARKQQSYSYLPAANSAITEELTTTALESDDKSEEQVPLPSKETANKKPDKSLLTASDLLDEPKEQEIQPSSTLPSVLADSVNKLDRQSTQPTVSAAEHLEKEVQKSAVQSYLPYAPSAKSSYSTPSETRQEDIIPKSSETAQSESGHVLLPHSLDVTEKQETECHLSATAQSETDHSGLLYSVKKKESQRTPLPEIQNICLEKQTKSEQDLFFAQEAEEQVIKLNSHTPEKMDSKYFGISYPVCTETQETRKKSVVNKALDLDRPVFSVDKNNQAESAQMEMEYPDFSYSNEESGESEILQTETEHPDFSFSKEVTGQFESAQLKTDNPHFPYSTEETDKSKSSQGETEQPDFSFSREEVRESESAQLETVNPEFLFSKKEIEKSESPHLETEHPDFSYSREEMMESKSAQLEMEQSDFSFSREEIEDSESAQPKIEHPDFSYFREEMVESDDAHMKMEQPDFSFSREEIEDSESAQPKIEHPDFSYSREEMVESDYAHMKMEQPDISLTREETRELESTQLETKHPEFDFSKEDMQESESTQMETEHPDFSYSREKMVKTESAQLEQTDFSFSREETEESESAQLETKHRDFLFSREETEGQKSIPFELEQPKSYSPEEAEHERTAQLELEPSDISCSMEEAEKENTTELELVHPDISDFAGRDRMQHMGHKETRHSDLPYPMDETKHQDLAQVDNNKPLLSYFDDRGEQPQPVQKDLQPGGKLYSLGNSMQGETNQLHSECPVLPYSAAKEQQHKEESDTSYLTGKTDQEIFQSKVEHADFPYFCGEAAQEAVQKDVGSPEWSSFTSETQQSEITQLASENRDLSFTTGEIVQEEMKSGSSYSSHSIDRPTHRQMVQLEQEHLLPTYSSPDSQQEETTPLDLPQPDISYSTGKVKQENRVQRGQEEMVEIQSEATQKELDYSDLTENWGKAETRDMDQMNLAQQETTEPELEHPPLPYSFSELMQEEKEVESAYPEQTFYASIDMKEKVTQQKTKQPFLSCFTGKKEDEIMHPEQEQTSVPFSSGKEAPLEMEMGSEYPDVSYSSHRPEQEKFRHPTLPFSSKEQEAAPPVIEHPDFSYNTGELKPGDTIQQESEYPEKSYSMEEMQQESEYLDSPETLGRAQDETVEMESEYPDVSCSDDQKSQQETSQLASKYPGTLFSFSDFKEQATQEFDSKHKDLPRVARKRALPETAQIDSKYPDLTYSFGKAEEPEISQSEARHSDLSHSTGETNKSDLLDQKHIKISVDREKQQQTPEEQVEQEKFSYSSSKTEQLKYAEEGFEKQDLSFSSVRPDEKMALTETEHAAVINPLEKAEVQQRVQLESEQMDLTRPFEKEEQKMAQPEAERSRLAHSVGTAELEEIAEPAQRYPDLPYSVFKVGKLQSEELKPEHPGLACSFNKVKEITQLNVLDTHDKTEECPLAKLELGNEDLASPADKIGQQGMVHTALECPDENQSASRAQHPQPTKEKLEVPDISSHSGNEEQRGMAKPVLKHPDLSYSTHGTQPQKNTQLELGKPDLATWPGKTEQAQPAQKEQSGFLHSFYKEEAQPEMGRSQVSYSVSETEQEIAHEESIHSDLSAGRLKQHEFIQPEAEIMDLSCLVGEPQQSQIDELDLEYPDLSHSTGALQKQEEVQPELEEPSDFSSSLRKEQGENARMQAECSEFQSSVWKAERLQDSQVESERTDLSFSVTIAESHETTPSVLKELDLLRSSVKTMQSWDSPEPDHLNISNAVAKVPHPDMFSSTSEEKQSAQVDFKQERESCALHTEEMTKLKLEQPTLSSAHGTVEQPRRTSMEGEFLDTSRLSGEKRENRKEKRDMSRQELEHLSDLSDLTDKTQQQETTQPESRQSDLSSYSGKKEQPQTVQVEGEHQELLRFPGETQRQGTAEPEVEHSDLSYSIGKVEQPQATQWKSEQPVAPHHIGTTDQQGIAHSVQDLGQDFIYDPGKTDEIQTVQGELEHTALLYSSDKTEQEMVMSELQHPQLSYSVRVIEEKTAHQKSDNKDLSYSTCHQEHHKTVQPEMEEMDLSYPTEKSEHSQSAQIVLQKPGFLKSFGKLEEKGLAQPSFLHSVGEEKQKPSSELDLMQPCLSHLLDKAEKQETAQEVFMSSDFSYSMGKADQLQTEQVKLKYPDFSYSLDKAETHGVKPLGLLSSYSKAEQTQTAHPEHPETSYVAGRTEKKDGIHPELQCFNLPSSAVEVEQQETFSVSYTSARTEEQQTAELKSEQSDLLNSTEKVEKGEIAESRAGHSEKWNTGIISSLTTLLETEQDLSFSTKEATSQKTQPFSSLPEKSVSVPLGVSHSETKVERNPKSSPVTGSLSSEHLDLSYSRCKTEPSETAQPVSGFFSTRKEAENTRIHLHLPMSAQSEAEHVILPETEREQTPHYFHTTPQLESEKLSTTYCIDKAETLEGQEYLTAPSKLETESSAPFYSVDETHQQEILPYSKPASENLFAEYSLAEQEKQSMKLVIPQSAQSECKHVTPPHDEAELQKNQVYSPKPASLKTEQFENKTIVHRKERDEQDLTECLSLEQLSSPKLSVKWDKQEVQPDVQKVPQLVSAESKATAVADQQSVSSDPFVPFHAVSEKTVSVSFTDDKEKQNIPSSLPNILGIPENQTNIVSGSYTKEEDRHGMQPYFTGQKHSSLEQPRSVSSDLVCDTVAHKTRHYSCEQGTLYSMESKPIFPSSNEKQNPDIPSPGLASWLAEEVKAHSINPIPAKGVDKLSPNEASDLGSKQFPAGNFTEVAVHGTTDNKGDTFRVSDSETEISCGLSSEAGHRAGRHDLPSPRADNPGSDKGPESETRFGNPTKRKAAQHLEEDKMSEVSEHYLRREEEEMKHMSTVEDSQHAPEPIEQKDLFNIISEGYEILNIHAPTHISSIDQEESKHMPDKLEYLETNPSFKKKIAHERHEASASETTEISGISVLGMSESHEVKELVKTEDAGETEEIQEENPVLSESKNHAVLDPDNGISEIDYFEKYTLIDDKSPIKPHFERPSSSFPVKEDLNEPVEQATSSKETAEEDTLEEEFALLEDLDEVFYGTVKGESKMESYAGASEPFPLQKSIDISSKKTTSVEDEQKSPGTPLFDSEEGVLERSLLFPTTVAAVNPELLEEPPALSFLYKDLYAEAVGEKTKDETPSDEESGNSNASFPSRNSDTDDGTGIYFEKYILKDEIPGKVLEPQKDQIPEDESFSGGISVPSSEEKYKQTSADALSVRTETVPEREIVEKVHSDIKATICKPTHAIPFGGRVIVSGARSDVTEQREENVPVETTEELPEQTSQQGYSQIVDSLGAAHRESINKQEEHREITAAPQVEQYVPYNRTPVEDSEDDQYTQEIVSHVPTIQQREKPDFQREEQHPHVYEDFAESMDYDVITQEELLQDEISSELTHEELLFEDRDSFEHIGDSYEFFNEPEQRTPVELEDSGFVVMYPEKSAANIPEIESPQRELKKAQTDTYCYHCKCPISAIDKLFGEHKDHEVTTLDDAATKMKDHLGELLIALEKKSMKIEEFVSDIESLFNSVEENCKKNAELLEKQNEEMLKKMVAQYDEKSENFEEVKRMKMEYLYEQMVNFQQTVDSAKETLETTVKEMEELNGFAFLNSSKELNKRLCSAMDATLSLEKVPSTFSLFEHYVDSPGKSNQNSLKHVAVPQTPTLIPQEPNSATSTSIAVYWTVNEGDAIDCFQVYCMEELQASKDEGALVEEYRVTVKESHCILEDLEPDRCYSVWVMAVNCTGCSLPSEKSIFKTAPAIPTIKAEDCTVCWDTATIRWQVASAAAESFTLEYCRQHSPEGEGLRSFAGIKRHELKVSLEPNVNYFFYLRAVNTFGTSEQSEAALISTKGTRFHILSDTAHPALQISPDETIICLPEKATFTGFPSVLGELLPARGCHYWETVVTACRSYRIGICYETTPQSSDVGLSDTSWCMHCCPTQTSFLYRFFHMDVMSDVHVTEQLARIGILLDYNGGRLLFFNAERGLVLFTIRHKFTDAVYPAFALDKAGMLTLHTGMDLPEFVKHS", "length": 4413, "header": "tr|A0A8V0YFL5-1|A0A8V0YFL5_CHICK Isoform 1 of Cardiomyopathy associated 5 OS=Gallus gallus OX=9031 GN=CMYA5 PE=4 SV=1 CANONICAL=A0A8V0YFL5-1" }, "locus": { "chromosome": "Z", "start_pos": 22713878, "end_pos": 22666593, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029733.1", "url": "https://www.ensembl.org/id/ENSGALT00010029733.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017309.1", "url": "https://www.ensembl.org/id/ENSGALP00010017309.1" } ] } }, { "isoform_ac": "A0A8V0YHP6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFL5/entry#A0A8V0YHP6-1", "sequence": { "sequence": "MEGYRGAECDRASETSSFIEDEEEEEEEEEEEEEEEEEAVDPEEAEELTHSLKDLIQSEDVKPKLQYIMTNPSFSMVTVQSEDSGITWETSSSRCSTPWTSETSTTSDLYSMESSPVGSPPGKVIFIMDEGKIVRKRKRKPSNRMPLPTHVIGGQGNKKRDFSGMQRQEPRTVLGDVHGSVLNVEQMEAQDIDEDMLEDREDLENIAEQPVKRAPIRSIFRESRLRKVGPILGGPVKSRIQLFNSIFGGTGPLPETLEKGRIQRKSSVSGELECFLEASVKERSHKFISETTHTKSFQRTSRSFETPSERRRNQRQQSTAQSNQSYSSVTPLEKQLSSKDVAFKNIKPVKTKDKPSKFSKSGEETTFQHEERKDRQSQLENLNQVSGKSQKFSPPKEARKQQSYSYLPAANSAITEELTTTALESDDKSEEQVPLPSKETANKKPDKSLLTASDLLDEPKEQEIQPSSTLPSVLADSVNKLDRQSTQPTVSAAEHLEKEVQKSAVQSYLPYAPSAKSSYSTPSETRQEDIIPKSSETAQSESGHVLLPHSLDVTEKQETECHLSATAQSETDHSGLLYSVKKKESQRTPLPEIQNICLEKQTKSEQDLFFAQEAEEQVIKLNSHTPEKMDSKYFGISYPVCTETQETRKKSVVNKALDLDRPVFSVDKNNQAESAQMEMEYPDFSYSNEESGESEILQTETEHPDFSFSKEVTGQFESAQLKTDNPHFPYSTEETDKSKSSQGETEQPDFSFSREEVRESESAQLETVNPEFLFSKKEIEKSESPHLETEHPDFSYSREEMMESKSAQLEMEQSDFSFSREEIEDSESAQPKIEHPDFSYFREEMVESDDAHMKMEQPDFSFSREEIEDSESAQPKIEHPDFSYSREEMVESDYAHMKMEQPDISLTREETRELESTQLETKHPEFDFSKEDMQESESTQMETEHPDFSYSREKMVKTESAQLEQTDFSFSREETEESESAQLETKHRDFLFSREETEGQKSIPFELEQPKSYSPEEAEHERTAQLELEPSDISCSMEEAEKENTTELELVHPDISDFAGRDRMQHMGHKETRHSDLPYPMDETKHQDLAQVDNNKPLLSYFDDRGEQPQPVQKDLQPGGKLYSLGNSMQGETNQLHSECPVLPYSAAKEQQHKEESDTSYLTGKTDQEIFQSKVEHADFPYFCGEAAQEAVQKDVGSPEWSSFTSETQQSEITQLASENRDLSFTTGEIVQEEMKSGSSYSSHSIDRPTHRQMVQLEQEHLLPTYSSPDSQQEETTPLDLPQPDISYSTGKVKQENRVQRGQEEMVEIQSEATQKELDYSDLTENWGKAETRDMDQMNLAQQETTEPELEHPPLPYSFSELMQEEKEVESAYPEQTFYASIDMKEKVTQQKTKQPFLSCFTGKKEDEIMHPEQEQTSVPFSSGKEAPLEMEMGSEYPDVSYSSHRPEQEKFRHPTLPFSSKEQEAAPPVIEHPDFSYNTGELKPGDTIQQESEYPEKSYSMEEMQQESEYLDSPETLGRAQDETVEMESEYPDVSCSDDQKSQQETSQLASKYPGTLFSFSDFKEQATQEFDSKHKDLPRVARKRALPETAQIDSKYPDLTYSFGKAEEPEISQSEARHSDLSHSTGETNKSDLLDQKHIKISVDREKQQQTPEEQVEQEKFSYSSSKTEQLKYAEEGFEKQDLSFSSVRPDEKMALTETEHAAVINPLEKAEVQQRVQLESEQMDLTRPFEKEEQKMAQPEAERSRLAHSVGTAELEEIAEPAQRYPDLPYSVFKVGKLQSEELKPEHPGLACSFNKVKEITQLNVLDTHDKTEECPLAKLELGNEDLASPADKIGQQGMVHTALECPDENQSASRAQHPQPTKEKLEVPDISSHSGNEEQRGMAKPVLKHPDLSYSTHGTQPQKNTQLELGKPDLATWPGKTEQAQPAQKEQSGFLHSFYKEEAQPEMGRSQVSYSVSETEQEIAHEESIHSDLSAGRLKQHEFIQPEAEIMDLSCLVGEPQQSQIDELDLEYPDLSHSTGALQKQEEVQPELEEPSDFSSSLRKEQGENARMQAECSEFQSSVWKAERLQDSQVESERTDLSFSVTIAESHETTPSVLKELDLLRSSVKTMQSWDSPEPDHLNISNAVAKVPHPDMFSSTSEEKQSAQVDFKQERESCALHTEEMTKLKLEQPTLSSAHGTVEQPRRTSMEGEFLDTSRLSGEKRENRKEKRDMSRQELEHLSDLSDLTDKTQQQETTQPESRQSDLSSYSGKKEQPQTVQVEGEHQELLRFPGETQRQGTAEPEVEHSDLSYSIGKVEQPQATQWKSEQPVAPHHIGTTDQQGIAHSVQDLGQDFIYDPGKTDEIQTVQGELEHTALLYSSDKTEQEMVMSELQHPQLSYSVRVIEEKTAHQKSDNKDLSYSTCHQEHHKTVQPEMEEMDLSYPTEKSEHSQSAQIVLQKPGFLKSFGKLEEKGLAQPSFLHSVGEEKQKPSSELDLMQPCLSHLLDKAEKQETAQEVFMSSDFSYSMGKADQLQTEQVKLKYPDFSYSLDKAETHGVKPLGLLSSYSKAEQTQTAHPEHPETSYVAGRTEKKDGIHPELQCFNLPSSAVEVEQQETFSVSYTSARTEEQQTAELKSEQSDLLNSTEKVEKGEIAESRAGHSEKWNTGIISSLTTLLETEQDLSFSTKEATSQKTQPFSSLPEKSVSVPLGVSHSETKVERNPKSSPVTGSLSSEHLDLSYSRCKTEPSETAQPVSGFFSTRKEAENTRIHLHLPMSAQSEAEHVILPETEREQTPHYFHTTPQLESEKLSTTYCIDKAETLEGQEYLTAPSKLETESSAPFYSVDETHQQEILPYSKPASENLFAEYSLAEQEKQSMKLVIPQSAQSECKHVTPPHDEAELQKNQVYSPKPASLKTEQFENKTIVHRKERDEQDLTECLSLEQLSSPKLSVKWDKQEVQPDVQKVPQLVSAESKATAVADQQSVSSDPFVPFHAVSEKTVSVSFTDDKEKQNIPSSLPNILGIPENQTNIVSGSYTKEEDRHGMQPYFTGQKHSSLEQPRSVSSDLVCDTVAHKTRHYSCEQGTLYSMESKPIFPSSNEKQNPDIPSPGLASWLAEEVKAHSINPIPAKGVDKLSPNEASDLGSKQFPAGNFTEVAVHGTTDNKGDTFRVSDSETEISCGLSSEAGHRAGRHDLPSPRADNPGSDKGPESETRFGNPTKRKAAQHLEEDKMSEVSEHYLRREEEEMKHMSTVEDSQHAPEPIEQKDLFNIISEGYEILNIHAPTHISSIDQEESKHMPDKLEYLETNPSFKKKIAHERHEASASETTEISGISVLGMSESHEVKELVKTEDAGETEEIQEENPVLSESKNHAVLDPDNGISEIDYFEKYTLIDDKSPIKPHFERPSSSFPVKEDLNEPVEQATSSKETAEEDTLEEEFALLEDLDEVFYGTVKGESKMESYAGASEPFPLQKSIDISSKKTTSVEDEQKSPGTPLFDSEEGVLERSLLFPTTVAAVNPELLEEPPALSFLYKDLYAEAVGEKTKDETPSDEESGNSNASFPSRNSDTDDGTGIYFEKYILKDEIPGKVLEPQKDQIPEDESFSGGISVPSSEEKYKQTSADALSVRTETVPEREIVEKVHSDIKATICKPTHAIPFGGRVIVSGARSDVTEQREENVPVETTEELPEQTSQQGYSQIVDSLGAAHRESINKQEEHREITAAPQVEQYVPYNRTPVEDSEDDQYTQEIVSHVPTIQQREKPDFQREEQHPHVYEDFAESMDYDVITQEELLQDEISSELTHEELLFEDRDSFEHIGDSYEFFNEPEQRTPVELEDSGFVVMYPEKSAANIPEIESPQRELKKAQTDTYCYHCKCPISAIDKLFGEHKDHEVTTLDDAATKMKDHLGELLIALEKKSMKIEEFVSDIESLFNSVEENCKKNAELLEKQNEEMLKKMVAQYDEKSENFEEVKRMKMEYLYEQMVNFQQTVDSAKETLETTVKEMEELNGFAFLNVMFCNGCYSFFRKGAQYIFTV", "length": 4018, "header": "tr|A0A8V0YHP6-1|A0A8V0YHP6_CHICK Computationally mapped isoform of Cardiomyopathy associated 5 OS=Gallus gallus OX=9031 GN=CMYA5 PE=4 SV=1 CANONICAL=A0A8V0YFL5-1" }, "locus": { "chromosome": "Z", "start_pos": 22713878, "end_pos": 22688323, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029730.1", "url": "https://www.ensembl.org/id/ENSGALT00010029730.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017305.1", "url": "https://www.ensembl.org/id/ENSGALP00010017305.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 521, "start_aa": "Thr", "end_pos": 521, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr521", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:427177", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427177", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFL5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFL5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1044, "end_pos": 1046, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1631, "end_pos": 1633, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1853, "end_pos": 1855, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2127, "end_pos": 2129, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2629, "end_pos": 2631, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2907, "end_pos": 2909, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3012, "end_pos": 3014, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3137, "end_pos": 3139, "annotation": "n_glycosylation_sequon" }, { "start_pos": 323, "end_pos": 325, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3543, "end_pos": 3545, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3717, "end_pos": 3719, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3997, "end_pos": 3999, "annotation": "n_glycosylation_sequon" }, { "start_pos": 4129, "end_pos": 4131, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YFL5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFL5" }, { "id": "PS50188", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50188" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "B30.2/SPRY", "eco_id": "ECO_0000259", "start_pos": 4221, "end_pos": 4409, "start_aa": "Asn", "end_aa": "Phe", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0YFL5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFL5" }, { "id": "PS50853", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50853" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Fibronectin type-III", "eco_id": "ECO_0000259", "start_pos": 4046, "end_pos": 4147, "start_aa": "Val", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 521 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1044, "end_pos": 1046 }, { "start_pos": 1631, "end_pos": 1633 }, { "start_pos": 1853, "end_pos": 1855 }, { "start_pos": 2127, "end_pos": 2129 }, { "start_pos": 2629, "end_pos": 2631 }, { "start_pos": 2907, "end_pos": 2909 }, { "start_pos": 3012, "end_pos": 3014 }, { "start_pos": 3137, "end_pos": 3139 }, { "start_pos": 323, "end_pos": 325 }, { "start_pos": 3543, "end_pos": 3545 }, { "start_pos": 3717, "end_pos": 3719 }, { "start_pos": 3997, "end_pos": 3999 }, { "start_pos": 4129, "end_pos": 4131 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", 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"total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YGL4-1", "uniprot_ac": "A0A8V0YGL4", "uniprot_id": "A0A8V0YGL4_CHICK", "mass": { "chemical_mass": 59800.0, "monoisotopic_mass": 59800.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Uncharacterized protein", "type": "synonym", "evidence": [ { "id": "A0A8V0YGL4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGL4/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGL4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGL4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGL4", "locus": {} } ], "crossref": [ { "id": "A0A8V0YGL4", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YGL4", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR001584", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001584", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002156", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002156", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012337", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012337", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036397", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036397", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR41694", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR41694", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR41694:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR41694:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00075", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00075", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00665", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00665", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0Y887", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y887", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y887-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y887-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YEG6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEG6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YEG6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEG6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YGL4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGL4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YGL4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGL4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YGM8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGM8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YGM8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGM8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YGN3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGN3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YGN3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGN3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLE0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLE0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLE0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLE0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLE9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLE9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLE9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLE9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVEKQLLATYSALQAVEPITQTAEVIVKTTLPIQGWVKDLTHIPKTGVAQSQTVARWVAYRSQRSRLSSSPLKEELQKILGPVTYHSETPEEIVVTCPEKSPVQEGKYPIPEDAWYTDGSSRGNPSRWRAVAYHPSTETIWFEEGDGQSSQWAELRAVWMVITQEPGNSALNICTDSWAVYRGLTLWIAQWATQDWTIHARPIWGKDMWVDIWNVVRHRTVRAYHVSGHQPLQSPGNDEADTLARVRWLGSTPSEDIAHWLHRKLRHAGPKTMWAAAKAWGLPIQLPDIVQACQDCDACSRMRPRPLPETTAHLARGHNPLQRWQIDYIGPLPRSEGARYALTCVDTESGLMQAYPVAKANQAYTIKALTRLMASYGTPEVIESDQGTHFTGATVQKWAEDNNTEWRFPLPYNPTGAGLIERYNGILKAALKADSQSLQGWTKRLYETLRDLNERPRGGRPSALRMLQTTWASPLRIQITSKDTSVKPQVGTMNNLLPAPDDLEPGRHKVKWPWKVQAGPKWCGLLAPSGR", "length": 531, "header": "tr|A0A8V0YGL4-1|A0A8V0YGL4_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0YGL4-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Y887-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGL4/entry#A0A8V0Y887-1", "sequence": { "sequence": "MQAYPVAKANQASTIKALTRLMASYGTPEVIESDQGTHFTGATVQKWAEDNNIEWRFHLPYNPTGAGLIERYNGILKAALKADSHSLQGWTKRLYETLRDLNERPRDGRPSALRMLQTTWASPLRIQITSKDT", "length": 133, "header": "tr|A0A8V0Y887-1|A0A8V0Y887_CHICK Computationally mapped isoform of Integrase catalytic domain-containing protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0YGL4-1" }, "locus": { "chromosome": "W", "start_pos": 6326797, "end_pos": 5959699, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029165.1", "url": "https://www.ensembl.org/id/ENSGALT00010029165.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016911.1", "url": "https://www.ensembl.org/id/ENSGALP00010016911.1" } ] } }, { "isoform_ac": "A0A8V0YEG6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGL4/entry#A0A8V0YEG6-1", "sequence": { "sequence": "MVITQEPGNSALNICTDSWAVYRGLTLWIAQWATQDWTIHARPIWGKDMWVDIWNVVRHRTVRAYHVSGHQPLQSPGNDEADTLARVRWLGSTPSEDIAHWLHRKLRHAGPKTMWAAAKAWGLPIQLPDIVQACQDCDACSRMRPRPLPETTAHLARGHNPLQRWQIDYIGPLPRSEGAKYALTCVDTASGLMQAYPVAKANQAYTIKALTRLMASYGTPEVIESDQGTHFTGATVQKWAEDNNIEWRFHLPYNPTGAGLIERYNGILKAALKADSQSLQGWTKRLYETLRDLNERPRDGRPSALRMLQTTWASPLRIQITSKDTSLKPQVGTMNNLLLPAPDDLEPGRHKVKWPWKVQAGPKWCGLLAPWGRLLEVGGSVNPSVIGVWPTEVVVDTPVFIAKGTLIMSMWQIRTPPLVPNIVIQSQISGQRVWYRRPGRAPIQAEVLTQDRNTACILPWRADLPLLVPIKHLFYSP", "length": 477, "header": "tr|A0A8V0YEG6-1|A0A8V0YGL4_CHICK Computationally mapped isoform of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0YGL4-1" }, "locus": { "chromosome": "W", "start_pos": 6233229, "end_pos": 6049981, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029153.1", "url": "https://www.ensembl.org/id/ENSGALT00010029153.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016902.1", "url": "https://www.ensembl.org/id/ENSGALP00010016902.1" } ] } }, { "isoform_ac": "A0A8V0YGL4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGL4/entry#A0A8V0YGL4-1", "sequence": { "sequence": "MVEKQLLATYSALQAVEPITQTAEVIVKTTLPIQGWVKDLTHIPKTGVAQSQTVARWVAYRSQRSRLSSSPLKEELQKILGPVTYHSETPEEIVVTCPEKSPVQEGKYPIPEDAWYTDGSSRGNPSRWRAVAYHPSTETIWFEEGDGQSSQWAELRAVWMVITQEPGNSALNICTDSWAVYRGLTLWIAQWATQDWTIHARPIWGKDMWVDIWNVVRHRTVRAYHVSGHQPLQSPGNDEADTLARVRWLGSTPSEDIAHWLHRKLRHAGPKTMWAAAKAWGLPIQLPDIVQACQDCDACSRMRPRPLPETTAHLARGHNPLQRWQIDYIGPLPRSEGARYALTCVDTESGLMQAYPVAKANQAYTIKALTRLMASYGTPEVIESDQGTHFTGATVQKWAEDNNTEWRFPLPYNPTGAGLIERYNGILKAALKADSQSLQGWTKRLYETLRDLNERPRGGRPSALRMLQTTWASPLRIQITSKDTSVKPQVGTMNNLLPAPDDLEPGRHKVKWPWKVQAGPKWCGLLAPSGR", "length": 531, "header": "tr|A0A8V0YGL4-1|A0A8V0YGL4_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0YGL4-1" }, "locus": { "chromosome": "W", "start_pos": 6180886, "end_pos": 6049504, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029148.1", "url": "https://www.ensembl.org/id/ENSGALT00010029148.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016898.1", "url": "https://www.ensembl.org/id/ENSGALP00010016898.1" } ] } }, { "isoform_ac": "A0A8V0YGM8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGL4/entry#A0A8V0YGM8-1", "sequence": { "sequence": "MQAYPVAKANQASTIKALTRLMASYGTPEVIESDQGTHFTGATVQKWAEDNNIEWRFHLPYNPTGAGLIERYNGILKAALKADSQSLQGWTKRLYETLRDLNERPRDGRPSALRMLQTTWASPLRIQITSKDTSLKPQVGTMNNLLLPAPDDLEPGRHKLAQ", "length": 162, "header": "tr|A0A8V0YGM8-1|A0A8V0YGM8_CHICK Computationally mapped isoform of Integrase catalytic domain-containing protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0YGL4-1" }, "locus": { "chromosome": "W", "start_pos": 6326822, "end_pos": 5959699, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029169.1", "url": "https://www.ensembl.org/id/ENSGALT00010029169.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016914.1", "url": "https://www.ensembl.org/id/ENSGALP00010016914.1" } ] } }, { "isoform_ac": "A0A8V0YGN3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGL4/entry#A0A8V0YGN3-1", "sequence": { "sequence": "MVEKQLLATYSALQAVEPITQTAEVIVKTTLPIQGWVKDLTHIPKTGVAQSQTVARWVAYRSQRSRLSSSPLKEELQKILGPVTYHSETPEEIVVTCPEKSPVQEGKYPIPEDAWYTDGSSRGNPSRWRAVAYHPSTETIWFEEGDGQSSQWAELRAVWMVITQEPGNSALNICTDSWAVYRGLTLWIAQWATQDWTIHARPIWGKDMWVDIWNVVRHRTVRAYHVSGHQPLQSPGNDEADTLARVRWLGSTPSEDIAHWLHRKLRHAGPKTMWAAAKAWGLPIQLPDIVQACQDCDACSRMRPRPLPETTAHLARGHNPLQRWQIDYIGPLPRSEGARYALTCVDTESGLMQAYPVAKANQAYTIKALTRLMASYGTPEVIESDQGTHFTGATVQKWAEDNNIEWRFHLPYNPTGAGLIERYNGILKAALKADSQSLQGWTKRLYETLRDLNERPRDGRPSALRMLQTTWASPLRIQITSKDTSLKPQ", "length": 489, "header": "tr|A0A8V0YGN3-1|A0A8V0YGN3_CHICK Computationally mapped isoform of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0YGL4-1" }, "locus": { "chromosome": "W", "start_pos": 6326812, "end_pos": 6049504, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029175.1", "url": "https://www.ensembl.org/id/ENSGALT00010029175.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016919.1", "url": "https://www.ensembl.org/id/ENSGALP00010016919.1" } ] } }, { "isoform_ac": "A0A8V0YLE0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGL4/entry#A0A8V0YLE0-1", "sequence": { "sequence": "MWAAAKAWGLPIQLPDIVQACQDCDACSRMRPRPLPETTAHLARGHNPLQRWQIDYIGPLPRSEGAKYALTCVDTASGLMQAYPVAKANQAYTIKALTRLMASYGTPEVIESDQGTHFTGATVQKWAEDNNIEWRFHLPYNPTGAGLIERYNGILKAALKADSQSLQGWTKRLYETLRDLNERPRDGRPSALRMLQTTWASPLRIQITSKDTSLKPQVGTMNNLLLPAPDDLEPGRHKVKWPWKVQAGPKWCGLLAPWGRLLEVGGSVNPSVIGVWPTEVVVDTPVFIAKGTLIMSMWQIRTPPLVPNIVIQSQISGQRVWYRRPGRAPIQAEVLTQDRNTACILPWRADLPLLVPIKHLFYSP", "length": 364, "header": "tr|A0A8V0YLE0-1|A0A8V0YLE0_CHICK Computationally mapped isoform of Integrase catalytic domain-containing protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0YGL4-1" }, "locus": { "chromosome": "W", "start_pos": 6233229, "end_pos": 5959462, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029160.1", "url": "https://www.ensembl.org/id/ENSGALT00010029160.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016907.1", "url": "https://www.ensembl.org/id/ENSGALP00010016907.1" } ] } }, { "isoform_ac": "A0A8V0YLE9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGL4/entry#A0A8V0YLE9-1", "sequence": { "sequence": "MQAYPVAKANQASTIKALTRLMASYGTPEVIESDQGTHFTGATVQKWAEDNNIEWRFHLPYNPTGAGLIERYNGILKAALKADSQSLQGWTKRLYETLRDLNERPRDGRPSALRMLQTTWASPLRIQITSKDTSLKPQVGTMNNLLLPAPDDLEPGRHKVKWPWKVQAGPKWCGLLAPWGRLLEVGGSVNPSVIGVWPTEVVVDTPVFIAKGTLIMSMWQIRTPPLVPDIVIQSQILGQRVWYRRPGRAPIQAEVLTQDRNTACILPWRADLPLLVPIKHLFYSP", "length": 285, "header": "tr|A0A8V0YLE9-1|A0A8V0YLE9_CHICK Computationally mapped isoform of Integrase catalytic domain-containing protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0YGL4-1" }, "locus": { "chromosome": "W", "start_pos": 6327254, "end_pos": 5959699, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029173.1", "url": "https://www.ensembl.org/id/ENSGALT00010029173.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016917.1", "url": "https://www.ensembl.org/id/ENSGALP00010016917.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 6, "go_terms": [ { "name": "RNA-directed DNA polymerase activity", "id": "GO:0003964", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003964", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGL4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGL4" } ], "pmid": "" }, { "name": "nucleic acid binding", "id": "GO:0003676", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003676", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGL4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGL4" } ], "pmid": "" }, { "name": "RNA-DNA hybrid ribonuclease activity", "id": "GO:0004523", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004523", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGL4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGL4" } ], "pmid": "" }, { "name": "RNA stem-loop binding", "id": "GO:0035613", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035613", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGL4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGL4" } ], "pmid": "" }, { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGL4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGL4" } ], "pmid": "" }, { "name": "endonuclease activity", "id": "GO:0004519", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004519", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGL4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGL4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "DNA integration", "id": "GO:0015074", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015074", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGL4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGL4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 402, "end_pos": 404, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YGL4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGL4" }, { "id": "PS50994", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50994" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Integrase catalytic", "eco_id": 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"https://www.uniprot.org/uniprotkb/A0A8V0YET8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BSM2", "url": "https://www.uniprot.org/uniprotkb/E1BSM2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BSM2-1", "url": "https://www.uniprot.org/uniprotkb/E1BSM2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVRFLIKLLLILGPFSYLDDVPFKIGDKFKTPAKVGLPIGFCMPDSFQLVREAQYDFSLEKKTIEWAEDIKKIQAAQKEAERKAEEAIANSKVAPEDNNRMGFSEGPCPEAMPPPINPILASLQHNSILTPTPANSSAVKQKVLSPPHPKADFNPADFECEEDPFDKLELKTIDDKEELKNILEIHVGTTGPVVAQLLDNSLPKGRSESVLQDQEVLASIERAALDLKPLHKPNGFITLPQLGNCEKMSLSSKVSLSPITSVSNIKSLSFPKLDSDESDQKSSKLMSTFHSTSCLRNGTFLSSLQACAQNKASELNGHHMVDLSAVNEDSGMEMSTLSSSSRLQSLALSTLCTEEQSTVTTVHPDKETEVPVVTHQNFPVSKVPNNTTCTKQSGFPELQQALSASERQCVETVVNMGYSPENVLKAMKKKGQNIDQVLDYLFAHGQLCEKGFDPLLVEAALEMHQCSEEKITELLQLMSQFKEMGFELKDIKEVLLLHNNDQQNALEDLMARAEAS", "length": 516, "header": "tr|A0A8V0YET8-1|A0A8V0YET8_CHICK Isoform 1 of Ubiquitin-associated protein 1 OS=Gallus gallus OX=9031 GN=UBAP1 PE=4 SV=1 CANONICAL=A0A8V0YET8-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YB69-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YET8/entry#A0A8V0YB69-1", "sequence": { "sequence": "MMFGLNKYDFSLEKKTIEWAEDIKKIQAAQKEAERKAEEAIANSKVAPEDNNRMGFSEGPCPEAMPPPINPILASLQHNSILTPTPANSSAVKQKVLSPPHPKADFNPADFECEEDPFDKLELKTIDDKEELKNILEIHVGTTGPVVAQLLDNSLPKGRSESVLQDQEVLASIERAALDLKPLHKPNGFITLPQLGNCEKMSLSSKVSLSPITSVSNIKSLSFPKLDSDESDQKSSKLMSTFHSTSCLRNGTFLSSLQACAQNKASELNGHHMVDLSAVNEDSGMEMSTLSSSSRLQSLALSTLCTEEQSTVTTVHPDKETEVPVVTHQNFPVSKVPNNTTCTKQSGFPELQQALSASERQCVETVVNMGYSPENVLKAMKKKGQNIDQVLDYLFAHGQLCEKGFDPLLVEAALEMHQCSEEKITELLQLMSQFKEMGFELKDIKEVLLLHNNDQQNALEDLMARAEAS", "length": 469, "header": "tr|A0A8V0YB69-1|A0A8V0YB69_CHICK Computationally mapped isoform of Ubiquitin-associated protein 1 OS=Gallus gallus OX=9031 GN=UBAP1 PE=4 SV=1 CANONICAL=A0A8V0YET8-1" }, "locus": { "chromosome": "Z", "start_pos": 8110835, "end_pos": 8102299, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028301.1", "url": "https://www.ensembl.org/id/ENSGALT00010028301.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016209.1", "url": "https://www.ensembl.org/id/ENSGALP00010016209.1" } ] } }, { "isoform_ac": "A0A8V0YCN4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YET8/entry#A0A8V0YCN4-1", "sequence": { "sequence": "MASKKLGSDSHGPFSYLDDVPFKIGDKFKTPAKVGLPIGFCMPDSFQLVREAQYDFSLEKKTIEWAEDIKKIQAAQKEAERKAEEAIANSKVAPEDNNRMGFSEGPCPEAMPPPINPILASLQHNSILTPTPANSSAVKQKVLSPPHPKADFNPADFECEEDPFDKLELKTIDDKEELKNILEIHVGTTGPVVAQLLDNSLPKGRSESVLQDQEVLASIERAALDLKPLHKPNGFITLPQLGNCEKMSLSSKVSLSPITSVSNIKSLSFPKLDSDESDQKSSKLMSTFHSTSCLRNGTFLSSLQACAQNKASELNGHHMVDLSAVNEDSGMEMSTLSSSSRLQSLALSTLCTEEQSTVHPDKETEVPVVTHQNFPVSKVPNNTTCTKQSGFPELQQALSASERQCVETVVNMGYSPENVLKAMKKKGQNIDQVLDYLFAHGQLCEKGFDPLLVEAALEMHQCSEEKITELLQLMSQFKEMGFELKDIKEVLLLHNNDQQNALEDLMARAEAS", "length": 512, "header": "tr|A0A8V0YCN4-1|A0A8V0YCN4_CHICK Computationally mapped isoform of Ubiquitin-associated protein 1 OS=Gallus gallus OX=9031 GN=UBAP1 PE=4 SV=1 CANONICAL=A0A8V0YET8-1" }, "locus": { "chromosome": "Z", "start_pos": 8110835, "end_pos": 8096633, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028336.1", "url": "https://www.ensembl.org/id/ENSGALT00010028336.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016237.1", "url": "https://www.ensembl.org/id/ENSGALP00010016237.1" } ] } }, { "isoform_ac": "A0A8V0YET8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YET8/entry#A0A8V0YET8-1", "sequence": { "sequence": "MVRFLIKLLLILGPFSYLDDVPFKIGDKFKTPAKVGLPIGFCMPDSFQLVREAQYDFSLEKKTIEWAEDIKKIQAAQKEAERKAEEAIANSKVAPEDNNRMGFSEGPCPEAMPPPINPILASLQHNSILTPTPANSSAVKQKVLSPPHPKADFNPADFECEEDPFDKLELKTIDDKEELKNILEIHVGTTGPVVAQLLDNSLPKGRSESVLQDQEVLASIERAALDLKPLHKPNGFITLPQLGNCEKMSLSSKVSLSPITSVSNIKSLSFPKLDSDESDQKSSKLMSTFHSTSCLRNGTFLSSLQACAQNKASELNGHHMVDLSAVNEDSGMEMSTLSSSSRLQSLALSTLCTEEQSTVTTVHPDKETEVPVVTHQNFPVSKVPNNTTCTKQSGFPELQQALSASERQCVETVVNMGYSPENVLKAMKKKGQNIDQVLDYLFAHGQLCEKGFDPLLVEAALEMHQCSEEKITELLQLMSQFKEMGFELKDIKEVLLLHNNDQQNALEDLMARAEAS", "length": 516, "header": "tr|A0A8V0YET8-1|A0A8V0YET8_CHICK Isoform 1 of Ubiquitin-associated protein 1 OS=Gallus gallus OX=9031 GN=UBAP1 PE=4 SV=1 CANONICAL=A0A8V0YET8-1" }, "locus": { "chromosome": "Z", "start_pos": 8110835, "end_pos": 8101100, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028307.1", "url": "https://www.ensembl.org/id/ENSGALT00010028307.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016213.1", "url": "https://www.ensembl.org/id/ENSGALP00010016213.1" } ] } }, { "isoform_ac": "E1BSM2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YET8/entry#E1BSM2-1", "sequence": { "sequence": "MASKKLGSDSHGPFSYLDDVPFKIGDKFKTPAKVGLPIGFCMPDSFQLVREAQYDFSLEKKTIEWAEDIKKIQAAQKEAERKAEEAIANSKVAPEDNNRMGFSEGPCPEAMPPPINPILASLQHNSILTPTPANSSAVKQKVLSPPHPKADFNPADFECEEDPFDKLELKTIDDKEELKNILEIHVGTTGPVVAQLLDNSLPKGRSESVLQDQEVLASIERAALDLKPLHKPNGFITLPQLGNCEKMSLSSKVSLSPITSVSNIKSLSFPKLDSDESDQKSSKLMSTFHSTSCLRNGTFLSSLQACAQNKASELNGHHMVDLSAVNEDSGMEMSTLSSSSRLQSLALSTLCTEEQSTVTTVHPDKETEVPVVTHQNFPVSKVPNNTTCTKQSGFPELQQALSASERQCVETVVNMGYSPENVLKAMKKKGQNIDQVLDYLFAHGQLCEKGFDPLLVEAALEMHQCSEEKITELLQLMSQFKEMGFELKDIKEVLLLHNNDQQNALEDLMARAEAS", "length": 515, "header": "tr|E1BSM2-1|E1BSM2_CHICK Computationally mapped isoform of Ubiquitin-associated protein 1 OS=Gallus gallus OX=9031 GN=UBAP1 PE=4 SV=4 CANONICAL=A0A8V0YET8-1" }, "locus": { "chromosome": "Z", "start_pos": 8110835, "end_pos": 8096633, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028313.1", "url": "https://www.ensembl.org/id/ENSGALT00010028313.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016219.1", "url": "https://www.ensembl.org/id/ENSGALP00010016219.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 132, "start_aa": "Thr", "end_pos": 132, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr132", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:431652", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:431652", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "F1SEB1-1", "protein_name": "Ubiquitin-associated protein 1", "gene_name": "UBAP1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MASKKLGADFHGTFSYLDDVPFKIGDKFKTPAKVGLPIGFSLPDCLQVVREVQYDFSLEKKTIEWAEDIKKIQEAQWEAERKAEEAEAKVNSKSGPEGDSKLSFSKTPGAAIMPPPINPILASLQHNSILTPTRVSSSATKQKVLSPPHTKADFNPADFECEEDPFDNLELKTIDEKEELRNILVGTTGPIMAQLLDSNLPRGGSGSVLQDEEVLASLERATLDFKPLHKPNGFVTLPQLGNCEKMSLSSKVSLPPIPAVSNIKSLSFPKLDSDDSSQKTAKMASTFHSTSCLRSGTLRNSLKPSTQSSASELNGHHTLGLSALNLDSGTEVPTPAPSQMPSLSVLSMCTEESSPPNTGPMITPPNLSMSQVPNTPGCPQAYSELQTLSPSERQCVETVVNMGYSYECVLRAMKKKGENIEQILDYLFAHGQLCEKGFDPLLVEEALEMHQCSEEKMMEFLQLMSKFKEMGFELKDIKEVLLLHNNDQDNALEDLMARAGAS", "length": 502 }, "evidence": [ { "id": "A0A8V0YET8", "url": "https://omabrowser.org/oma/group/A0A8V0YET8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F6P6X0-1", "protein_name": "Ubiquitin-associated protein 1", "gene_name": "ubap1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAARKSGSDIHNNGPVSYLDDVPFKLNEKFRCPSKVGLPIGFCLSDCNAILSDLQYDFNLERRTVQWGEELAKARAAEARAAEAIRTDSESERQAASQDAEVGLVGGKKARPSDEQDIVPPALKPVLAGLSHNAILTPLPAPSFGQTRPAPSNPAPQYLNLADFEREEDPFDKLELKTLDDKEELRTILQSQPQSSVSPPQLPPAEHRPVSPSTTPPLQAKTGIFHKPNGLVGLLDLDRGGVLGGQIDADRPCNIRSLTFPKLSDPGDSPLETPLSVYPVAPPRNLSNGTPPSLQRTASNNNTTLPQEQPVFAQNGTPKQSNPVTVTSHPPAGTTLLSLSPSERQCVETIVGMGYSYEGVLKAMQRQGQNVEQVLEYLFTHSRLCDRGFDATAVEECLEMYQGSEEKALEFLQLMSRFGEMGFERDTIKEVLLVHNNDQDKALEDLMTRATAS", "length": 453 }, "evidence": [ { "id": "A0A8V0YET8", "url": "https://omabrowser.org/oma/group/A0A8V0YET8/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "G3I852-1", "protein_name": "Ubiquitin-associated protein 1", "gene_name": "Ubap1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MASKKLGSDFHGTFSYLDDVPFKIGDKFKTPAKVGLPIGFSMPDCLQVIREVQYDFSLEKKTIEWAEDVKLIQEAQREAERKAEDAEAKVNSKSGPEGDSKMSFSKTHNTATMPPPINPILASLQHNSILTPTRVSSSATKQKVLSPPHTKADFNPADFECEEDPFDNLELKTIDEKEELRNILVGTTGPIMAQLLDSNSPRGSPGSVLQDEEVLASLEQATLDFKPLHKPNGFITLPQLGNCEKMSLSSKVSLPPIPTVSNIKSLSFPKLDSDDSNQKTVKLASTFHSTSCLRSGTSRNFLKPSTQSSASELNGDHALGLSALNLNSGTEVPTMTSSQMPSLSVLSVCTEESSPPNTCPTVTPLNFSVSQVPSCPQAYLELQALSPSERQCVETVVNMGYSYDCVLRAMKKKGENIEQILDYLFAHGQLCEKGFDPLLVEEALEMHQCSEEKMMEFLQLMSKFKEMGFELKDIKEVLLLHNNDQDNALEDLMARAGAS", "length": 499 }, "evidence": [ { "id": "A0A8V0YET8", "url": "https://omabrowser.org/oma/group/A0A8V0YET8/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q5XIS7-1", "protein_name": "Ubiquitin-associated protein 1", "gene_name": "Ubap1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASKKLGTDFHGTFSYLDDVPFKIGDKFKTPAKVGLPIGFSLPDCLQVVREMQYDFSLEKKAIEWAEDIRLIQEAQQEAERKSEEAEAKVNSKSGPEGDSKVSFSKTHSPATMPPPINPILASLQHNNILTPTRVSSSATKQKVLSPPHTKADFNPADFECEEDPFDNLELKTIDEKEELRNILVGTTGPIMAQLLDSNTPRGNSGSVLQDEEVLASLEQATLDFKPLHKPNGFITLPQLGNCEKMSLSSKVSLPPIPTVSNIKSLSFPKLDSDDSSQKTVRLASTFHSTSCLRSGASRNFLKPSTQSSASELNGDHALGLSALNLNSGTEVPALTSSQMPSLSILSVCTEESSPPSTCPTVTPLNFSVSQVPTMPSCPQAYLELQALSPSERQCVETVVNMGYSYDCVLRAMKKKGENIEQILDYLFAHGQLCEKGFDPLLVEEALEMHQCSEEKMMEFLQLMSKFKEMGFELKDIKEVLLLHNNDQDNALEDLMARAEAS", "length": 502 }, "evidence": [ { "id": "A0A8V0YET8", "url": "https://omabrowser.org/oma/group/A0A8V0YET8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8BH48-1", "protein_name": "Ubiquitin-associated protein 1", "gene_name": "Ubap1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASKKLGTDVHGTFSYLDDVPFKIGDKFKTPAKVGLPIGFSLPDCLQVVREMQYDFSLEKKTIEWAEDIKLIQEAQREAERKAEEAEAKVNSKSGPEGDSKVSFPKTHNTATMPPPINPILASLQHNNILTPTRVSSSATKQKVLSPPHTKADFNPADFECEEDPFDNLELKTIDEKEELRNILVGTTGPIMAQLLDSNTARGSSGAVLQDEEVLASLEQATLDFKPLHKPNGFITLPQLGNCEKMSLSSKVSLPPIPTVSNIKSLSFPKLDSDDSNQKTVKLASTFHSTSCLRSGASRSLLKPSTQSSASELNGDHTLGLSALNLNSGTEVPTLTSSQMPSLSSVSVCTEESSPPDPCPTVTPLNFSVSQVPNMPSCPQAYLELQALSPSERQCVETVVNMGYSYDCVLRAMRKKGENIEQILDYLFAHGQLCEKGFDPLLVEEALEMHQCSEEKMMEFLQLMSKFKEMGFELKDIKEVLLLHNNDQDNALEDLMARAGAS", "length": 502 }, "evidence": [ { "id": "A0A8V0YET8", "url": "https://omabrowser.org/oma/group/A0A8V0YET8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9NZ09-1", "protein_name": "Ubiquitin-associated protein 1", "gene_name": "UBAP1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MASKKLGADFHGTFSYLDDVPFKTGDKFKTPAKVGLPIGFSLPDCLQVVREVQYDFSLEKKTIEWAEEIKKIEEAEREAECKIAEAEAKVNSKSGPEGDSKMSFSKTHSTATMPPPINPILASLQHNSILTPTRVSSSATKQKVLSPPHIKADFNLADFECEEDPFDNLELKTIDEKEELRNILVGTTGPIMAQLLDNNLPRGGSGSVLQDEEVLASLERATLDFKPLHKPNGFITLPQLGNCEKMSLSSKVSLPPIPAVSNIKSLSFPKLDSDDSNQKTAKLASTFHSTSCLRNGTFQNSLKPSTQSSASELNGHHTLGLSALNLDSGTEMPALTSSQMPSLSVLSVCTEESSPPNTGPTVTPPNFSVSQVPNMPSCPQAYSELQMLSPSERQCVETVVNMGYSYECVLRAMKKKGENIEQILDYLFAHGQLCEKGFDPLLVEEALEMHQCSEEKMMEFLQLMSKFKEMGFELKDIKEVLLLHNNDQDNALEDLMARAGAS", "length": 502 }, "evidence": [ { "id": "A0A8V0YET8", "url": "https://omabrowser.org/oma/group/A0A8V0YET8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YET8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YET8" } ], "pmid": "" }, { "name": "ubiquitin binding", "id": "GO:0043130", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043130", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YET8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YET8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YET8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YET8" } ], "pmid": "" }, { "name": "ESCRT I complex", "id": "GO:0000813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000813", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YET8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YET8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YET8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YET8" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YET8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YET8" } ], "pmid": "" }, { "name": "ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway", "id": "GO:0043162", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043162", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YET8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YET8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 135, "end_pos": 137, "annotation": "n_glycosylation_sequon" }, { "start_pos": 297, "end_pos": 299, "annotation": "n_glycosylation_sequon" }, { "start_pos": 385, "end_pos": 387, "annotation": "n_glycosylation_sequon" }, { "start_pos": 386, "end_pos": 388, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YET8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YET8" }, { "id": "PS50937", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50937" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "HTH merR-type", "eco_id": "ECO_0000259", "start_pos": 473, "end_pos": 497, "start_aa": "Glu", "end_aa": "Leu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0YET8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YET8" }, { "id": "PS50030", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50030" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "UBA", "eco_id": "ECO_0000259", "start_pos": 403, "end_pos": 444, "start_aa": "Ser", "end_aa": "His", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0YET8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YET8" }, { "id": "PS51497", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51497" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "UMA", "eco_id": "ECO_0000259", "start_pos": 18, "end_pos": 64, "start_aa": "Leu", "end_aa": "Ile", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 132 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 135, "end_pos": 137 }, { "start_pos": 297, "end_pos": 299 }, { "start_pos": 385, "end_pos": 387 }, { "start_pos": 386, "end_pos": 388 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { 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"n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YEU4-1", "uniprot_ac": "A0A8V0YEU4", "uniprot_id": "A0A8V0YEU4_CHICK", "mass": { "chemical_mass": 44845.0, "monoisotopic_mass": 44845.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Uncharacterized protein", "type": "synonym", "evidence": [ { "id": "A0A8V0YEU4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEU4/entry#names_and_taxonomy" } ] } ], "function": [], 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"UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGSVWGDGTPWQPYGVAASYGVAALWGHSLMGSQPYGVAALWGRSGVMGPQPRGVSAPWGHSHVGSQPYGVAAVRGLSPMGLQPCGVAALWGLSFTGSQPYGVAAVRGLSPMGLQPYGVAAPWCLSLMGSQPYGVSALWGPSPMGSQLYGVPALWGLSFMGSQLCGVPALWGPSRVGSQPYGVSALWGLSPMGSQPYGVSALWGLSPMGSQPYGVPALRGLSFMGSQPCGVSALWGPSPMGSQPYGVSALQGRSPMGSQPYGVSALWGPSPMGSQPYGVPALRGPSPMGSQPYGVPALRGLSPMGSQPYGVSALWGPSPMGSRLRLSPSPTSKSLKGRLWGRRLPARRRGGCGAGPTPHASPPWSPPRTRSTISPSAPRSSAPHGRCASYRGRGASPEPLWGRGGGAVGSPHRATHSPRGNPIGKPVALVDPQTPPLAP", "length": 439, "header": "tr|A0A8V0YEU4-1|A0A8V0YEU4_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0YEU4-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YEU4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEU4/entry#A0A8V0YEU4-1", "sequence": { "sequence": "MGSVWGDGTPWQPYGVAASYGVAALWGHSLMGSQPYGVAALWGRSGVMGPQPRGVSAPWGHSHVGSQPYGVAAVRGLSPMGLQPCGVAALWGLSFTGSQPYGVAAVRGLSPMGLQPYGVAAPWCLSLMGSQPYGVSALWGPSPMGSQLYGVPALWGLSFMGSQLCGVPALWGPSRVGSQPYGVSALWGLSPMGSQPYGVSALWGLSPMGSQPYGVPALRGLSFMGSQPCGVSALWGPSPMGSQPYGVSALQGRSPMGSQPYGVSALWGPSPMGSQPYGVPALRGPSPMGSQPYGVPALRGLSPMGSQPYGVSALWGPSPMGSRLRLSPSPTSKSLKGRLWGRRLPARRRGGCGAGPTPHASPPWSPPRTRSTISPSAPRSSAPHGRCASYRGRGASPEPLWGRGGGAVGSPHRATHSPRGNPIGKPVALVDPQTPPLAP", "length": 439, "header": "tr|A0A8V0YEU4-1|A0A8V0YEU4_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0YEU4-1" }, "locus": { "chromosome": "38", "start_pos": 155311, "end_pos": 153048, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010025733.1", "url": "https://www.ensembl.org/id/ENSGALT00010025733.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010014504.1", "url": "https://www.ensembl.org/id/ENSGALP00010014504.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 357, "start_aa": "Thr", "end_pos": 357, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr357", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 357 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YEV1-1", "uniprot_ac": "A0A8V0YEV1", "uniprot_id": "A0A8V0YEV1_CHICK", "mass": { "chemical_mass": 41612.0, "monoisotopic_mass": 41612.0 }, "refseq": { "ac": "XP_418989", "name": "MARVEL domain-containing protein 3 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_418989" }, "gene_names": [ { "name": "LOC420903", "type": "recommended", "evidence": [ { "id": "A0A8V0YEV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEV1" } ] }, { "name": "LOC420903", "type": "synonym", "evidence": [ { "id": "XP_418989", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_418989" } ] } ], "protein_names": [ { "name": "MARVEL domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A8V0YEV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEV1/entry#names_and_taxonomy" } ] }, { "name": "MARVEL domain-containing protein 3 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_418989", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_418989" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052533.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_418989.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_418989", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_418989" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YEV1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEV1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LOC420903", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEV1", "locus": {} } ], "crossref": [ { "id": "A0A8V0YEV1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YEV1", "database": "AlphaFoldDB", "categories": [] }, { "id": "420903", "url": "https://www.ncbi.nlm.nih.gov/gene/420903", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR008253", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008253", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050578", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050578", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:420903", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420903", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "SHAGSRY", "url": "https://omabrowser.org/oma/group/SHAGSRY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YEV1", "url": "https://www.orthodb.org/?gene=A0A8V0YEV1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22776", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22776", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22776:SF98", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22776:SF98", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "XP_418989", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_418989", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YEV1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEV1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YEV1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEV1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAQVLPRARGPPPRGGRSGGGRGRIWPGREPELRAALRKLFLKERVHVRDKMAHAGRRYQDKQGRYHENHGSDGYEEDRKTRKPSPYNGRSAKDTRGGQHSRASIVCSEPYSKASAASQEYFEPPPQYYPTKETLSMKCSKVCTTRGILKFVEITVNLLVLICVGAAQASVAGFTSVGGLGIGSFNLNSAYSPFEGTELQEVRELDMQITQMRAPCVYGGVAFSLAAAALTLVFLVVGAKPIHRLKMGLLGGECTFNLLAGVGYIVAVGLYLHFVTQVNATEACKRRERLYARRGYTSMNCVVQGGDAAVGLFGVAAACLYFASFVVCILAIRTVRAFQSRMAKAQHSPKSSVRDRSVRNDRPVHRPSESSHNIQALATLV", "length": 381, "header": "tr|A0A8V0YEV1-1|A0A8V0YEV1_CHICK Isoform 1 of MARVEL domain-containing protein OS=Gallus gallus OX=9031 GN=LOC420903 PE=4 SV=1 CANONICAL=A0A8V0YEV1-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YEV1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEV1/entry#A0A8V0YEV1-1", "sequence": { "sequence": "MAQVLPRARGPPPRGGRSGGGRGRIWPGREPELRAALRKLFLKERVHVRDKMAHAGRRYQDKQGRYHENHGSDGYEEDRKTRKPSPYNGRSAKDTRGGQHSRASIVCSEPYSKASAASQEYFEPPPQYYPTKETLSMKCSKVCTTRGILKFVEITVNLLVLICVGAAQASVAGFTSVGGLGIGSFNLNSAYSPFEGTELQEVRELDMQITQMRAPCVYGGVAFSLAAAALTLVFLVVGAKPIHRLKMGLLGGECTFNLLAGVGYIVAVGLYLHFVTQVNATEACKRRERLYARRGYTSMNCVVQGGDAAVGLFGVAAACLYFASFVVCILAIRTVRAFQSRMAKAQHSPKSSVRDRSVRNDRPVHRPSESSHNIQALATLV", "length": 381, "header": "tr|A0A8V0YEV1-1|A0A8V0YEV1_CHICK Isoform 1 of MARVEL domain-containing protein OS=Gallus gallus OX=9031 GN=LOC420903 PE=4 SV=1 CANONICAL=A0A8V0YEV1-1" }, "locus": { "chromosome": "2", "start_pos": 67707341, "end_pos": 67691146, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028326.1", "url": "https://www.ensembl.org/id/ENSGALT00010028326.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016228.1", "url": "https://www.ensembl.org/id/ENSGALP00010016228.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:420903", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420903", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0AC58I1U1-1", "protein_name": "Uncharacterized protein isoform X1", "gene_name": "si:ch211-191a24.4", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MVSIYLWYLWYLSIYLWYLWYLWYLSMVSIVSIVSMVSIYLSIYLSIYLSIYLSIYGIYGIYGIYLWYLSYLWYLSIYLSIYLSIYLSIYLSIYLSIYLSIYPSIHPSIHPSIHPSIHPSIYLSIYLSIYLSIYLWYLSTKYLSIYLSIYLSIYLSIYLSIYLSIYLSIVPSICPSIHPSIHPPIYLSIYLSIYLSIYLSIYLSIYLSIYLSIYLSIYLSIYLSLHLSIYLSIYLSIYLSIYLSIYLSIYTILKAIQTNKLSIYLSIYLSIYLSIYLTIYLSIYLSIYLSIYLSIYLSIYLSIYLSNMLSIYLSIYLSIYLSIYLSIYLSIYLSIYLSICLSVCLIYLSVCLSVFVCIVINKLNFYDGVVLSLFFFFFFFYKICKPLQTYTKVSFFHEAMSQPPRNQRTHRERNGEERRQNGEKRDRDPRSQQDRPSDRRPGNERTRSSGQSSYQTRGSQRPARSTSQREHMESKCTYICSRRGIVLICTVLTNALVLICIVAAHMSQLGMSAMGMGGTSFVDAIIPFEGTELQTVRNLDMQYGQMRAPGVYGGVAFSLTFGALSLLFVVSSGKPAHVLPRKLLIGQFAFQIIGAVAYVIAVGLYLHLVISVNSTEMCIMRERLYARNGYTWMNCSVNGGDASVALFGIITAILYAVGAVFTAKTIRDVDRFLKERDHFEAEQREEPRGPQTRPLNSDIYI", "length": 701 }, "evidence": [ { "id": "A0A8V0YEV1", "url": "https://omabrowser.org/oma/group/A0A8V0YEV1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "structural constituent of myelin sheath", "id": "GO:0019911", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019911", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YEV1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEV1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YEV1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEV1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "myelination", "id": "GO:0042552", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042552", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YEV1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEV1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 279, "end_pos": 281, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YEV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEV1" }, { "id": "PS51225", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51225" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "MARVEL", "eco_id": "ECO_0000259", "start_pos": 141, "end_pos": 333, "start_aa": "Lys", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 279, "end_pos": 281 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { 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{ "uniprot_canonical_ac": "A0A8V0YH07-1", "uniprot_ac": "A0A8V0YH07", "uniprot_id": "A0A8V0YH07_CHICK", "mass": { "chemical_mass": 78578.0, "monoisotopic_mass": 78578.0 }, "refseq": { "ac": "XP_015134123", "name": "X-linked interleukin-1 receptor accessory protein-like 2 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015134123" }, "gene_names": [ { "name": "IL1RAPL2", "type": "recommended", "evidence": [ { "id": "A0A8V0YH07", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH07" } ] }, { "name": "IL1RAPL2", "type": "synonym", "evidence": [ { "id": "XP_015134123", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015134123" } ] } ], "protein_names": [ { "name": "Interleukin 1 receptor accessory protein like 2", "type": "synonym", "evidence": [ { "id": "A0A8V0YH07", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH07/entry#names_and_taxonomy" } ] }, { "name": "X-linked interleukin-1 receptor accessory protein-like 2 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015134123", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015134123" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052535.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015134123", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015134123" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YH07", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH07" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "IL1RAPL2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH07", "locus": { "chromosome": "4", "start_pos": 17138776, "end_pos": 16802416, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012259", "url": "https://www.ensembl.org/id/ENSGALG00010012259" } ] } } ], "crossref": [ { "id": "A0A8V0YH07", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YH07", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd05757", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05757", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd05896", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05896", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "422379", "url": "https://www.ncbi.nlm.nih.gov/gene/422379", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000157", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000157", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003598", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003598", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013098", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013098", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015621", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015621", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035897", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035897", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:422379", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422379", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QEPEVVW", "url": "https://omabrowser.org/oma/group/QEPEVVW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YEW7", "url": "https://www.orthodb.org/?gene=A0A8V0YEW7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YH07", "url": "https://www.orthodb.org/?gene=A0A8V0YH07", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11890", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11890", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11890:SF10", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11890:SF10", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01582", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01582", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07679", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07679", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13895", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13895", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-388844", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-388844", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_015134123", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015134123", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YEW7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEW7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YEW7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEW7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YH07", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH07", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YH07-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH07-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKPLVLLVLVICTVVSMNLKLVSKRNSVDGCIDWSVDLKTYMALAGEPVRVKCALFYSYIRTNYSMAQSTGLRLMWYKNKGDLEEPIIFSEVRMSKDEDSIWFHSVDLQDSGFYTCVLRNSTYCMKVSMSLTVAENESGLCYNSKIRYLEKSEVTKRKTISCPDIEDYKIDSQEPDVVWYKECKPKMWRSVVIQKGNTLLIQEVQEEDGGNYTCELKFEGKLIRRTVELKVTALLTDKPPKPLFPMENQPTVIDVQLGNPLTVACKAFFGFSGESGPMIYWMKGEKFIEELEGHIREGEIRLLREHLGEKEVELTLIFDAVEEADLANYTCHVENRNGRKHASILLRKKDLIYKIELAGGLGAILLLLILLVTIYKCYNIELMLFYRQNFGGDEAADDNKEYDAYLSYTKVDPDALDCDNNEEEQFALEILPDVLEKHYGYKLFIPDRDLIPSGTYIEDLTRCVEQSRRLIIVLTPDYILRRGWSIFEMESRLHNMLVSGEIKVILIECTELKGKVNYHEVESLKHTIKLLSVVKWKGPKSSKLNSKFWKRLVFEMPGKKKEVVSRRQVLDSAEQGLFGDLQTVPSLAVTGTSATLVESRADLTDCHQADSVQMRHYCRGYEYDVSAATLPIASISNHHTYCNIPLTLLNGQLPLNNTMKDSQEFHRNNPLLPLSARELSFTSDIW", "length": 686, "header": "tr|A0A8V0YH07-1|A0A8V0YH07_CHICK Isoform 1 of Interleukin 1 receptor accessory protein like 2 OS=Gallus gallus OX=9031 GN=IL1RAPL2 PE=3 SV=1 CANONICAL=A0A8V0YH07-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YEW7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH07/entry#A0A8V0YEW7-1", "sequence": { "sequence": "MKPLVLLVLVICTVVSMNLKLVSKRNSVDGCIDWSVDLKTYMALAGEPVRVKCALFYSYIRTNYSMAQSTGLRLMWYKNKGDLEEPIIFSEVRMSKDEDSIWFHSVDLQDSGFYTCVLRNSTYCMKVSMSLTVAENESGLCYNSKIRYLEKSEVTKRKTISCPDIEDYKIDSQEPDVVWYKECKPKMWRSVVIQKGNTLLIQEVQEEDGGNYTCELKFEGKLIRRTVELKVTALLTDKPPKPLFPMENQPTVIDVQLGNPLTVACKAFFGFSGESGPMIYWMKGEKFIEELEGHIREGEIRLLREHLGEKEVELTLIFDAVEEADLANYTCHVENRNGRKHASILLRKKDNKEYDAYLSYTKVDPDALDCDNNEEEQFALEILPDVLEKHYGYKLFIPDRDLIPSGTYIEDLTRCVEQSRRLIIVLTPDYILRRGWSIFEMESRLHNMLVSGEIKVILIECTELKGKVNYHEVESLKHTIKLLSVVKWKGPKSSKLNSKFWKRLVFEMPGKKKEVVSRRQVLDSAEQGLFGDLQTVPSLAVTGTSATLVESRADLTDCHQADSVQMRHYCRGYEYDVSAATLPIASISNHHTYCNIPLTLLNGQLPLNNTMKDSQEFHRNNPLLPLSARELSFTSDIW", "length": 638, "header": "tr|A0A8V0YEW7-1|A0A8V0YH07_CHICK Computationally mapped isoform of Interleukin 1 receptor accessory protein like 2 OS=Gallus gallus OX=9031 GN=IL1RAPL2 PE=3 SV=1 CANONICAL=A0A8V0YH07-1" }, "locus": { "chromosome": "4", "start_pos": 17136511, "end_pos": 16812876, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029373.1", "url": "https://www.ensembl.org/id/ENSGALT00010029373.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017059.1", "url": "https://www.ensembl.org/id/ENSGALP00010017059.1" } ] } }, { "isoform_ac": "A0A8V0YH07-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH07/entry#A0A8V0YH07-1", "sequence": { "sequence": "MKPLVLLVLVICTVVSMNLKLVSKRNSVDGCIDWSVDLKTYMALAGEPVRVKCALFYSYIRTNYSMAQSTGLRLMWYKNKGDLEEPIIFSEVRMSKDEDSIWFHSVDLQDSGFYTCVLRNSTYCMKVSMSLTVAENESGLCYNSKIRYLEKSEVTKRKTISCPDIEDYKIDSQEPDVVWYKECKPKMWRSVVIQKGNTLLIQEVQEEDGGNYTCELKFEGKLIRRTVELKVTALLTDKPPKPLFPMENQPTVIDVQLGNPLTVACKAFFGFSGESGPMIYWMKGEKFIEELEGHIREGEIRLLREHLGEKEVELTLIFDAVEEADLANYTCHVENRNGRKHASILLRKKDLIYKIELAGGLGAILLLLILLVTIYKCYNIELMLFYRQNFGGDEAADDNKEYDAYLSYTKVDPDALDCDNNEEEQFALEILPDVLEKHYGYKLFIPDRDLIPSGTYIEDLTRCVEQSRRLIIVLTPDYILRRGWSIFEMESRLHNMLVSGEIKVILIECTELKGKVNYHEVESLKHTIKLLSVVKWKGPKSSKLNSKFWKRLVFEMPGKKKEVVSRRQVLDSAEQGLFGDLQTVPSLAVTGTSATLVESRADLTDCHQADSVQMRHYCRGYEYDVSAATLPIASISNHHTYCNIPLTLLNGQLPLNNTMKDSQEFHRNNPLLPLSARELSFTSDIW", "length": 686, "header": "tr|A0A8V0YH07-1|A0A8V0YH07_CHICK Isoform 1 of Interleukin 1 receptor accessory protein like 2 OS=Gallus gallus OX=9031 GN=IL1RAPL2 PE=3 SV=1 CANONICAL=A0A8V0YH07-1" }, "locus": { "chromosome": "4", "start_pos": 17136511, "end_pos": 16812876, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029368.1", "url": "https://www.ensembl.org/id/ENSGALT00010029368.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017055.1", "url": "https://www.ensembl.org/id/ENSGALP00010017055.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:422379", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422379", "resource": "KEGG Pathway" }, { "id": "R-GGA-388844", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-388844", "resource": "Reactome", "description": "Receptor-type tyrosine-protein phosphatases" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A1W2Q6G2-1", "protein_name": "X-linked interleukin-1 receptor accessory protein-like 2", "gene_name": "Il1rapl2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKLPLLLALVVCSAVSTNLKMVSKRNSVDGCIDWSVDLKTYMALAGEPVRVKCALFYSYIRTNYSMAQSTGLRLMWYRNKGDLEEPIIFSEVRMSKEEDAIWFHSAEAQDSGFYTCVLRNSTYCMKVSMSLTVAENESGLCYNSRIRYLEKSEVTKRKEISCPDMDDFKKSDQEPDVVWYKECKPKMWRSIIIQKGNALLIQEVQEEDGGNYTCELKYEGKLVRRTTELKVTALLTDKPPKPLFPMENQPSVIDVQLGKPLNIPCKAFFGFSGESGPMIYWMKGEKFIEELAGHIREGEIRLLKEHLGEKEVELTLIFDSVVEADLANYTCHVENRNGRKHASVLLRKKDLIYKIELAGGLGAIFLLLILLLVVYKCYNIELMLFYRQRFGGDETTDDNKEYDAYLSYTKVDQDTLDCDNTEEEQFALEILPDVLEKHYGYKLFIPERDLIPSGTYIEDLTRCVEQSRRLIIVLTPDYILRRGWSIFELESRLHNMLVSGEIKVILIECTELKGKVNCPEVESLKHNIKLLSLIKWKGPKSSKLNSKFWKHLVYEMPIKKKEMLSHCHVLDSAEQGLFGELQPIPSIAMTSTSATMVPSQADLPEFHHSDSMQMRHCCRGYKHEMPANTLSVPSLGNHHTYCNLPLTLLNGQLPLNNSLKETEELSRNNPLLPLSSKELSFTSDIW", "length": 686 }, "evidence": [ { "id": "A0A8V0YH07", "url": "https://omabrowser.org/oma/group/A0A8V0YH07/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9ERS6-1", "protein_name": "X-linked interleukin-1 receptor accessory protein-like 2", "gene_name": "Il1rapl2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKLPLLLALVVCSAVSTNLKMVSKRNSVDGCIDWSVDLKTYMALAGEPVRVKCALFYSYIRTNYSMAQSTGLRLMWYRNKGDLEEPIIFSEVRMSKEEDAIWFHSAEEQDSGFYTCVLRNSTYCMKVSMSLTVAENESGLCYNSRIRYLEKSEVTKRKEISCPDMDDFKKSDQEPDVVWYKECKPKMWRSIIIQKGNALLIQEVQEEDGGNYTCELKYEGKLVRRTTELKVTALLTDKPPKPLFPMENQPSVIDVQLGKPLNIPCKAFFGFSGESGPMIYWMKGEKFIEELAGHIREGEIRLLKEHLGEKEVELTLIFDSVVEADLANYTCHVENRNGRKHASVLLRKKDLIYKIELAGGLGAIFLLLILLLVVYKCYNIELMLFYRQRFGGDETTDDNKEYDAYLSYTKVDQDTLDCDNTEEEQFALEILPDVLEKHYGYKLFIPERDLIPSGTYIEDLTRCVEQSRRLIIVLTPDYILRRGWSIFELESRLHNMLVSGEIKVILIECTELKGKVNCQEVESLKHNIKLLSLIKWKGPKSSKLNSKFWKHLVYEMPIKKKEMLSHCHVLDSAEQGLFGELQPIPSIAMTSTSATMVPSQADLPEFHHSDSMQMRHCCRGYQHEMPANTLSVPSLGNHHTYCNLPLTLLNGQLPLNNSLKETEEFSRNNPLLPLTSKELSFTSDIW", "length": 686 }, "evidence": [ { "id": "A0A8V0YH07", "url": "https://omabrowser.org/oma/group/A0A8V0YH07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9NP60-1", "protein_name": "X-linked interleukin-1 receptor accessory protein-like 2", "gene_name": "IL1RAPL2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKPPFLLALVVCSVVSTNLKMVSKRNSVDGCIDWSVDLKTYMALAGEPVRVKCALFYSYIRTNYSTAQSTGLRLMWYKNKGDLEEPIIFSEVRMSKEEDSIWFHSAEAQDSGFYTCVLRNSTYCMKVSMSLTVAENESGLCYNSRIRYLEKSEVTKRKEISCPDMDDFKKSDQEPDVVWYKECKPKMWRSIIIQKGNALLIQEVQEEDGGNYTCELKYEGKLVRRTTELKVTALLTDKPPKPLFPMENQPSVIDVQLGKPLNIPCKAFFGFSGESGPMIYWMKGEKFIEELAGHIREGEIRLLKEHLGEKEVELALIFDSVVEADLANYTCHVENRNGRKHASVLLRKKDLIYKIELAGGLGAIFLLLVLLVVIYKCYNIELMLFYRQHFGADETNDDNKEYDAYLSYTKVDQDTLDCDNPEEEQFALEVLPDVLEKHYGYKLFIPERDLIPSGTYMEDLTRYVEQSRRLIIVLTPDYILRRGWSIFELESRLHNMLVSGEIKVILIECTELKGKVNCQEVESLKRSIKLLSLIKWKGSKSSKLNSKFWKHLVYEMPIKKKEMLPRCHVLDSAEQGLFGELQPIPSIAMTSTSATLVSSQADLPEFHPSDSMQIRHCCRGYKHEIPATTLPVPSLGNHHTYCNLPLTLLNGQLPLNNTLKDTQEFHRNSSLLPLSSKELSFTSDIW", "length": 686 }, "evidence": [ { "id": "A0A8V0YH07", "url": "https://omabrowser.org/oma/group/A0A8V0YH07/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YH07", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH07" } ], "pmid": "" }, { "name": "nervous system development", "id": "GO:0007399", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007399", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YH07", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH07" } ], "pmid": "" }, { "name": "cell surface receptor signaling pathway", "id": "GO:0007166", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007166", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YH07", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH07" } ], "pmid": "" }, { "name": "regulation of presynapse assembly", "id": "GO:1905606", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905606", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YH07", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH07" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YH07", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH07" } ], "pmid": "" }, { "name": "synapse", "id": "GO:0045202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045202", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YH07", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH07" } ], "pmid": "" }, { "name": "glutamatergic synapse", "id": "GO:0098978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098978", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YH07", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH07" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YH07", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH07" } ], "pmid": "" }, { "name": "cell surface", "id": "GO:0009986", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009986", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YH07", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH07" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YH07", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH07" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 120, "end_pos": 122, "annotation": "n_glycosylation_sequon" }, { "start_pos": 136, "end_pos": 138, "annotation": "n_glycosylation_sequon" }, { "start_pos": 211, "end_pos": 213, "annotation": "n_glycosylation_sequon" }, { "start_pos": 328, "end_pos": 330, "annotation": "n_glycosylation_sequon" }, { "start_pos": 63, "end_pos": 65, "annotation": "n_glycosylation_sequon" }, { "start_pos": 656, "end_pos": 658, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YH07", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH07" }, { "id": "PS50835", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50835" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ig-like", "eco_id": "ECO_0000259", "start_pos": 3, "end_pos": 132, "start_aa": "Pro", "end_aa": "Thr", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0YH07", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH07" }, { "id": "PS50104", 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0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YEX1-1", "uniprot_ac": "A0A8V0YEX1", "uniprot_id": "A0A8V0YEX1_CHICK", "mass": { "chemical_mass": 9668.0, "monoisotopic_mass": 9668.0 }, "refseq": {}, "gene_names": [ { "name": "AvBD6", "type": "recommended", "evidence": [ { "id": "A0A8V0YEX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEX1" } ] } ], "protein_names": [ { "name": "Avian beta-defensin 6", "type": "synonym", "evidence": [ { "id": "A0A8V0YEX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEX1/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YEX1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEX1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "AvBD6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEX1", "locus": { "chromosome": "3", "start_pos": 107250114, "end_pos": 107248549, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010011870", "url": "https://www.ensembl.org/id/ENSGALG00010011870" } ] } } ], "crossref": [ { "id": "A0A8V0YEX1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YEX1", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR001855", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001855", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YBB7", "url": "https://www.orthodb.org/?gene=A0A8V0YBB7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YEX1", "url": "https://www.orthodb.org/?gene=A0A8V0YEX1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR20515", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR20515", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR20515:SF20", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR20515:SF20", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00711", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00711", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YBB7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBB7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YBB7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBB7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YEX1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEX1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YEX1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEX1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRILYLLLSVLFVVLQGVAGQPYFSSPIHACRYQRGVCIPGPCRWPYYRVGSCGSGLKSCCVSPAGTEDPQGLFMSHGSLCSGAMEYSR", "length": 89, "header": "tr|A0A8V0YEX1-1|A0A8V0YEX1_CHICK Isoform 1 of Avian beta-defensin 6 OS=Gallus gallus OX=9031 GN=AvBD6 PE=3 SV=1 CANONICAL=A0A8V0YEX1-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YBB7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEX1/entry#A0A8V0YBB7-1", "sequence": { "sequence": "MRILYLLLSVLFVVLQGVAGQPYFSSPIHACRYQRGVCIPGPCRWPYYRVGSCGSGLKSCCVRYVEVQGIPIAVADS", "length": 77, "header": "tr|A0A8V0YBB7-1|A0A8V0YBB7_CHICK Computationally mapped isoform of Avian beta-defensin 6 OS=Gallus gallus OX=9031 GN=AvBD6 PE=3 SV=1 CANONICAL=A0A8V0YEX1-1" }, "locus": { "chromosome": "3", "start_pos": 107249512, "end_pos": 107248577, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028356.1", "url": "https://www.ensembl.org/id/ENSGALT00010028356.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016249.1", "url": "https://www.ensembl.org/id/ENSGALP00010016249.1" } ] } }, { "isoform_ac": "A0A8V0YEX1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEX1/entry#A0A8V0YEX1-1", "sequence": { "sequence": "MRILYLLLSVLFVVLQGVAGQPYFSSPIHACRYQRGVCIPGPCRWPYYRVGSCGSGLKSCCVSPAGTEDPQGLFMSHGSLCSGAMEYSR", "length": 89, "header": "tr|A0A8V0YEX1-1|A0A8V0YEX1_CHICK Isoform 1 of Avian beta-defensin 6 OS=Gallus gallus OX=9031 GN=AvBD6 PE=3 SV=1 CANONICAL=A0A8V0YEX1-1" }, "locus": { "chromosome": "3", "start_pos": 107249640, "end_pos": 107248577, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028355.1", "url": "https://www.ensembl.org/id/ENSGALT00010028355.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016248.1", "url": "https://www.ensembl.org/id/ENSGALP00010016248.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": 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{ "uniprot_canonical_ac": "A0A8V0YEX6-1", "uniprot_ac": "A0A8V0YEX6", "uniprot_id": "A0A8V0YEX6_CHICK", "mass": { "chemical_mass": 101794.0, "monoisotopic_mass": 101794.0 }, "refseq": { "ac": "XP_003642959", "name": "junction-mediating and -regulatory protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003642959" }, "gene_names": [ { "name": "JMY", "type": "recommended", "evidence": [ { "id": "A0A8V0YEX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEX6" } ] }, { "name": "JMY", "type": "synonym", "evidence": [ { "id": "XP_003642959", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003642959" } ] } ], "protein_names": [ { "name": "Junction mediating and regulatory protein, p53 cofactor", "type": "synonym", "evidence": [ { "id": "A0A8V0YEX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEX6/entry#names_and_taxonomy" } ] }, { "name": "junction-mediating and -regulatory protein", "type": "synonym", "evidence": [ { "id": "XP_003642959", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003642959" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052572.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_003642959.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003642959", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003642959" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YEX6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEX6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "JMY", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEX6", "locus": { "chromosome": "Z", "start_pos": 22888345, "end_pos": 22944052, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012535", "url": "https://www.ensembl.org/id/ENSGALG00010012535" } ] } } ], "crossref": [ { "id": "A0A8V0YEX6", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YEX6", "database": "AlphaFoldDB", "categories": [] }, { "id": "427182", "url": "https://www.ncbi.nlm.nih.gov/gene/427182", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003124", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003124", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR031738", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031738", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR031808", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031808", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:427182", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427182", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PGEECSW", "url": "https://omabrowser.org/oma/group/PGEECSW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YEX6", "url": "https://www.orthodb.org/?gene=A0A8V0YEX6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23330", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23330", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23330:SF8", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23330:SF8", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15871", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15871", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF15920", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15920", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-6804760", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6804760", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_003642959", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003642959", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YEX6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEX6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YEX6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEX6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSAFALEETLEADWVAVRPHAFQEREKHKFVFIVAWNEIEGKFAITCHNRTAQRQRSGSREARAAPKASSPAARRGAEPALLSRAERAEALPGSPLRASRSGPTRKAARGAEAAAEEMEVLELGREEAAEAGAPEAEPAGEECSWAGLFSFQDLRAVHQQLCSVNSELEPYLPAFPEEPSGMWTVLFGAPELSEQEMDALCYRLQVYLVHSLDTCGWKILSQVLFTETDDPEEYYESLSELRQKGYEEVLQRARRRIQELLEKHKNTESMVELLELYQMEDEAYSSLAEATTELYQYLLQPFRDMRELAMLRRQQIKISIENDYLGPRRIESLQKEDADWQRKAHMAVLSIQDLTVKYFEITAKAQKAVYDRMRADQKKFGKAAWAAAVERMEKLQYAVSKETLQLMRAKEICLEQKKHALKEEMQSLKGGTEAIAHLDQLEADYYDLQLQLYEVQFEILKYEELLLTAQLESIRRLISEKRDEVVYYDTYESMEAMLEKEDPATSVHLQKEELQKLQQKIRQLEARRGRISAKKAYLRNKKEICIAKHNEKIQQRHQSEEEYKMHHTVQLKRDQLQDEEERKSSWVSQERQKTLDRLRTFKQRYPGQVILKSTRLRLAHARRKCAASSAPSVDQPQSLPATIQIQEKSEEVELENAVQPLRVQESTSLEQLQDISLPPSSVTSELPQVSPSPLISTELQTETVSVVPLPPPLPPPPLPPPPPLPSKEDTTKSLEKSGSFVKRQSEEKGVQHSSSVPTAYLFDSSQLVSAKKKLKKTGDLEGLQRRRVSSPMDEVLASLKRGSFHLRKVEQRSLPPFPDEDDSNNILAQIRKGVKLKKVQKDVLRESFTILPDTDPLTRSIHEALRRIKEASPESEDEEESLPCTDWEN", "length": 889, "header": "tr|A0A8V0YEX6-1|A0A8V0YEX6_CHICK Isoform 1 of Junction mediating and regulatory protein, p53 cofactor OS=Gallus gallus OX=9031 GN=JMY PE=4 SV=1 CANONICAL=A0A8V0YEX6-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YEX6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEX6/entry#A0A8V0YEX6-1", "sequence": { "sequence": "MSAFALEETLEADWVAVRPHAFQEREKHKFVFIVAWNEIEGKFAITCHNRTAQRQRSGSREARAAPKASSPAARRGAEPALLSRAERAEALPGSPLRASRSGPTRKAARGAEAAAEEMEVLELGREEAAEAGAPEAEPAGEECSWAGLFSFQDLRAVHQQLCSVNSELEPYLPAFPEEPSGMWTVLFGAPELSEQEMDALCYRLQVYLVHSLDTCGWKILSQVLFTETDDPEEYYESLSELRQKGYEEVLQRARRRIQELLEKHKNTESMVELLELYQMEDEAYSSLAEATTELYQYLLQPFRDMRELAMLRRQQIKISIENDYLGPRRIESLQKEDADWQRKAHMAVLSIQDLTVKYFEITAKAQKAVYDRMRADQKKFGKAAWAAAVERMEKLQYAVSKETLQLMRAKEICLEQKKHALKEEMQSLKGGTEAIAHLDQLEADYYDLQLQLYEVQFEILKYEELLLTAQLESIRRLISEKRDEVVYYDTYESMEAMLEKEDPATSVHLQKEELQKLQQKIRQLEARRGRISAKKAYLRNKKEICIAKHNEKIQQRHQSEEEYKMHHTVQLKRDQLQDEEERKSSWVSQERQKTLDRLRTFKQRYPGQVILKSTRLRLAHARRKCAASSAPSVDQPQSLPATIQIQEKSEEVELENAVQPLRVQESTSLEQLQDISLPPSSVTSELPQVSPSPLISTELQTETVSVVPLPPPLPPPPLPPPPPLPSKEDTTKSLEKSGSFVKRQSEEKGVQHSSSVPTAYLFDSSQLVSAKKKLKKTGDLEGLQRRRVSSPMDEVLASLKRGSFHLRKVEQRSLPPFPDEDDSNNILAQIRKGVKLKKVQKDVLRESFTILPDTDPLTRSIHEALRRIKEASPESEDEEESLPCTDWEN", "length": 889, "header": "tr|A0A8V0YEX6-1|A0A8V0YEX6_CHICK Isoform 1 of Junction mediating and regulatory protein, p53 cofactor OS=Gallus gallus OX=9031 GN=JMY PE=4 SV=1 CANONICAL=A0A8V0YEX6-1" }, "locus": { "chromosome": "Z", "start_pos": 22943853, "end_pos": 22889808, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030060.1", "url": "https://www.ensembl.org/id/ENSGALT00010030060.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017466.1", "url": "https://www.ensembl.org/id/ENSGALP00010017466.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:427182", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427182", "resource": "KEGG Pathway" }, { "id": "R-GGA-6804760", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6804760", "resource": "Reactome", "description": "Regulation of TP53 Activity through Methylation" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287BS45-1", "protein_name": "Junction mediating and regulatory protein, p53 cofactor", "gene_name": "JMY", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSFALEETLESDWVAVRPHVFDEREKHKFVFIVAWNEIEGKFAITCHNRTAQRQRSGTREQAGARGGAEPGVPASDGTRGPGSPVGRGRPEAIASTTLGRSPGPRRRPAWAEGGPPRSACSLRGDPLLRNSAGRGAESSLRSPVRTKSSPVRRASERRDVSAVPGAAAPPAPTEAQASSVRVVSACGTVTEEIEVLEMVREDEADPASLALSDAEQPPPAPELESPAEECSWAGLFSFQDLRAVHQQLCSVNSQLEPCLPVFPEEPSGMWTVLFGGAPEMTEQEIDTLCYQLQVYLGHGLDTCGWKILSQVLFTETDDPEEYYESLSELRQKGYEEVLQRARKRIQELLDKHKNTESMVELLDLYQMEDEAYSSLAEATTELYQYLLQPFRDMRELAMLRRQQIKISMENDYLGPRRIESLQKEDADWQRKAHMAVLSIQDLTVKYFEITAKAQKAVYDRMRADQKKFGKASWAAAAERMEKLQYAVSKETLQMMRAKEICLEQRKHALKEEMQSLQGGTEAIARLDQLEADYYDLQLQLYEVQFEILKCEELLLTAQLESIKRLISEKRDEVVYYDTYESMEAMLEKEEMAASVHLQREELQKLQQKARQLEARRGRVSAKKAYLRNKKEICIAKHNEKFQQRLQSEDEYRTHHTVQLKREKLHEEEERKSAWVSQERQKTLDRLRTFKQRYPGQVILKSTRLRLAHARRRSAASPVSCEDQCHSLPGAPQVEKSEEVEEGKGKLRSSQTTEAQSLTQLEDNSLAQLEATLLPLSGVTSELPPTVSLPLLNNIDLKSGSVSVDPLPPPLPPTPPPPPPPPPPPPPPPLPVGKDSTPETLEKGLPRVGGNEKRIPKSASAPSAHLFDSSQLVSARKKLKKTAEGLQRRRVSSPMDEVLASLKRGSFHLRKVEQRTLPPFPDEDDSNNILAQIRKGVKLKKVQKEVLRESFTLLPDTDPLTRSIHEALRRIKEASPESEDEEEALPCTDWEN", "length": 991 }, "evidence": [ { "id": "A0A8V0YEX6", "url": "https://omabrowser.org/oma/group/A0A8V0YEX6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "M0R8J3-1", "protein_name": "Junction mediating and regulatory protein, p53 cofactor", "gene_name": "Jmy", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSFALEETLESDWVAVRPHVFDEREKHKFVFIVAWNEIEGKFAITCHNRTAQRQRSGSREQTGTSASDGSRGPGSPAARGRPEAAASSTALRSPGPRKSQAWTESGSPRSARSLREDSLRGPLAKGPESPLRSPVRAKASPHRRGAESRDATAGATPTPPAPPVSSVRVVSASGAVSEEIEVLELVREDEAPQPLPDSEQSPSAAEQESPAEECSWAGLFSFQDLRAVHQQLCSVNSQLEPCLPVFPEEPSGMWTVLFGGAPEMTEQEIDALCYQLQVYLGHGLDTCGWKILSQVLFTETDDPEEYYESLSELRQKGYEEVLQRARRRIQELLDKHKTIESMVELLDLYQMEDEAYSSLAEATTELYQYLLQPFRDMRELAMLRRQQIKISMENDYLGPRRIESLQKEDADWQRKAHMAVLSIQDLTVKYFEITAKAQKAVYDRMRADQKKFGKASWAAAAERMEKLQYAVSKETLQMMRAKEICLEQKKHALKEEMQSLQGGTEAIAQLDQLEADYYALQLQLYEVQFEVLKCEELLLTAQLESIRRLVSEKRDEVVYYDTYESMEAMLEKEEVAASVHAQREELQKLQQKARQLEARRGRVSAKKAYLRNKKEICIAKHHEKFQQRFQSEDEYRAHHTIQLKRDKLHEEEERKSAWVSQERQRTLDRLRTFKQRYPGQVILKSTRLRAAHSRRKSTASPVPCEEQCDSLPAVLQGEGKAEAGEGRGQLGSSQTAEPRSLVQLEDTSSVQLESTSLPPRAVTSERPPPESAPLLTNSDPERCSVTIDPLPAPLPPTPPPPPPPPPPPPPPLPVAKDSGATTPAETLEKDALRTECGGKGIPKSASAPTAHLFDSSQLVSARRKLRKTAEGLQRRRVSSPMDEVLASLKRGSFHLKKVEQRTLPPFPDEDDSNNILAQIRKGVKLKKVQKEVLRESFTLLPDADPLTRSIHEALRRIKEASPESEDEDEALPGTDWEN", "length": 978 }, "evidence": [ { "id": "A0A8V0YEX6", "url": "https://omabrowser.org/oma/group/A0A8V0YEX6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8N9B5-1", "protein_name": "Junction-mediating and -regulatory protein", "gene_name": "JMY", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSFALEETLESDWVAVRPHVFDEREKHKFVFIVAWNEIEGKFAITCHNRTAQRQRSGSREQAGARGGAEAGGAASDGSRGPGSPAGRGRPEATASATLVRSPGPRRSSAWAEGGSPRSTRSLLGDPRLRSPGSKGAESRLRSPVRAKPIPGQKTSEADDAAGAAAAAARPAPREAQVSSVRIVSASGTVSEEIEVLEMVKEDEAPLALSDAEQPPPATELESPAEECSWAGLFSFQDLRAVHQQLCSVNSQLEPCLPVFPEEPSGMWTVLFGGAPEMTEQEIDTLCYQLQVYLGHGLDTCGWKILSQVLFTETDDPEEYYESLSELRQKGYEEVLQRARKRIQELLDKHKNTESMVELLDLYQMEDEAYSSLAEATTELYQYLLQPFRDMRELAMLRRQQIKISMENDYLGPRRIESLQKEDADWQRKAHMAVLSIQDLTVKYFEITAKAQKAVYDRMRADQKKFGKASWAAAAERMEKLQYAVSKETLQMMRAKEICLEQRKHALKEEMQSLRGGTEAIARLDQLEADYYDLQLQLYEVQFEILKCEELLLTAQLESIKRLISEKRDEVVYYDTYESMEAMLEKEEMAASAYLQREELQKLQQKARQLEARRGRVSAKKSYLRNKKEICIAKHNEKIQQRTRIEDEYRTHHTVQLKREKLHDEEERKSAWVSQERQRTLDRLRTFKQRYPGQVILKSTRLRLAHARRKGAASPVLQEDHCDSLPSVLQVEEKTEEVGEGRVKRGPSQTTEPQSLVQLEDTSLTQLEATSLPLSGVTSELPPTISLPLLNNNLEPCSVTINPLPSPLPPTPPPPPPPPPPPPPPPLPVAKDSGPETLEKDLPRKEGNEKRIPKSASAPSAHLFDSSQLVSARKKLRKTAEGLQRRRVSSPMDEVLASLKRGSFHLKKVEQRTLPPFPDEDDSNNILAQIRKGVKLKKVQKDVLRESFTLLPDTDPLTRSIHEALRRIKEASPESEDEEEALPCTDWEN", "length": 988 }, "evidence": [ { "id": "A0A8V0YEX6", "url": "https://omabrowser.org/oma/group/A0A8V0YEX6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9QXM1-1", "protein_name": "Junction-mediating and -regulatory protein", "gene_name": "Jmy", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSFALEETLESDWVAVRPHVFDEREKHKFVFIVAWNEIEGKFAITCHNRTAQRQRSGSREQAGTPASDGSRGPGSPAARGRSEAAASATAALRSPGPRKSQAWAEGGSPRSARSLKGDPPRGPAGRGPESPLRSPARAKASPLRRSAESRDAIASATPVPPAPPVPPVSSVRVVSASGAVSEEIEVLEMVREDEAPQPLPDSEQPPSAAELESSAEECSWAGLFSFQDLRAVHQQLCSVNSQLEPCLPVFPEEPSGMWTVLFGGAPEMTEQEIDALCYQLQVYLGHGLDTCGWKILSQVLFTETDDPEEYYESLSELRQKGYEEVLQRARRRIQELLDKHKTIESMVELLDLYQMEDEAYSSLAEATTELYQYLLQPFRDMRELAMLRRQQIKISMENDYLGPRRIESLQKEDADWQRKAHMAVLSIQDLTVKYFEITAKAQKAVYDRMRADQKKFGKASWAAAAERMEKLQYAVSKETLQMMRAKEICLEQKKHALKEEMQSLQGGTEAIARLDQLESDYYDLQLQLYEVQFEILKCEELLLTAQLESIKRLISEKRDEVVYYDTYESMEAMLEKEEMAASVHAQREELQKLQQKARQLEARRGRVSAKKAYLRNKKEICIAKHHEKFQQRFQSEDEYRAHHTIQIKRDKLHDEEERKSAWVSQERQRTLDRLRTFKQRYPGQVILKSTRLRVAHSRRKSTASPVPCEEQCHSLPTVLQGQEKTEVGGGGSQLGPSQTAEPQSLVQLEDTSSEQLESTSLPPRAVVSSELPPPQSAPLLTSIDPKPCSVTIDPLPPPLPPTPPPPPPPPPPPPPPLPVAKDNGASTTAETLEKDALRTEGNERSIPKSASAPAAHLFDSSQLVSARKKLRKTVEGLQRRRVSSPMDEVLASLKRGSFHLKKVEQRTLPPFPDEDDSNNILAQIRKGVKLKKVQKEVLRESFTLLPDTDPLTRSIHEALRRIKEASPESEDEEEALPCTDWEN", "length": 983 }, "evidence": [ { "id": "A0A8V0YEX6", "url": "https://omabrowser.org/oma/group/A0A8V0YEX6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "'de novo' actin filament nucleation", "id": "GO:0070060", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070060", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YEX6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEX6" } ], "pmid": "" }, { "name": "positive regulation of apoptotic process", "id": "GO:0043065", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043065", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YEX6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEX6" } ], "pmid": "" }, { "name": "Arp2/3 complex-mediated actin nucleation", "id": "GO:0034314", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034314", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YEX6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEX6" } ], "pmid": "" }, { "name": "intrinsic apoptotic signaling pathway by p53 class mediator", "id": "GO:0072332", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072332", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YEX6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEX6" } ], "pmid": "" }, { "name": "cellular response to starvation", "id": "GO:0009267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009267", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YEX6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEX6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "autophagosome membrane", "id": "GO:0000421", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000421", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YEX6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEX6" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YEX6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEX6" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YEX6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEX6" } ], "pmid": "" }, { "name": "cell leading edge", "id": "GO:0031252", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031252", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YEX6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEX6" } ], "pmid": "" }, { "name": "cytoplasmic vesicle membrane", "id": "GO:0030659", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030659", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YEX6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEX6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "transcription 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"tr|A0A8V0YEY1-1|A0A8V0YEY1_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0YEY1-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YEY1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEY1/entry#A0A8V0YEY1-1", "sequence": { "sequence": "MTFLNNFMGWFGRGKASPISEVLPGHILGFLGSPYHGIACIIEKWGPLRDAGNVQESPARLAEYFSSLNKNVLTTRERQLAASTVAWPLLMALNWLNITAEALTDENQLLRDRVEELERQVAILRGKKPNPIIPVQKIRNISLEITGDPIHDNPHELDSENEGTKKSDLEAPLELDPFEIRPVVTQKTKKTQDRPAGLPPDQWPPAQSTLHVTARPYTAAELMDLVQRFRQKPRESVPAWLLRLYDMGAESVVVNGPEISKLASITTHPALRQRLYAAVQHNEENHSLIAWLMAACCATWANKTDIPLNTGLWSSMEDLQNYIRELGMKEAIYEENFESPDMIKFSAGMRDLILQQAPPHQYGTLVSILNPLVASEAIIQQAAQLVADLGETERLRARCIVRMVVEKSDIHPPPRPRRPAPNVIQSGPIRISRKQMFSDLIRAGVQFQKIDGQPNQVLLQLWKQLPNSQRFQRSPKREGVRLIERIPQNTWNLEDFIVPSKKRKPPQVARAATVEPSEEKDLGIAELMA", "length": 529, "header": "tr|A0A8V0YEY1-1|A0A8V0YEY1_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0YEY1-1" }, "locus": { 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"database": "UniProtKB", "id": "A0A8V0YEY1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEY1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 140, "end_pos": 142, "annotation": "n_glycosylation_sequon" }, { "start_pos": 285, "end_pos": 287, "annotation": "n_glycosylation_sequon" }, { "start_pos": 302, "end_pos": 304, "annotation": "n_glycosylation_sequon" }, { "start_pos": 97, "end_pos": 99, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 140, "end_pos": 142 }, { "start_pos": 285, "end_pos": 287 }, { "start_pos": 302, "end_pos": 304 }, { "start_pos": 97, "end_pos": 99 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YEZ5-1", "uniprot_ac": "A0A8V0YEZ5", "uniprot_id": "A0A8V0YEZ5_CHICK", "mass": { "chemical_mass": 141412.0, "monoisotopic_mass": 141412.0 }, "refseq": { "ac": "XP_040511061", "name": "BRD4-interacting chromatin-remodeling complex-associated protein isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040511061" }, "gene_names": [ { "name": "BICRA", "type": "recommended", "evidence": [ { "id": "A0A8V0YEZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEZ5" } ] }, { "name": "BICRA", "type": "synonym", "evidence": [ { "id": "XP_040511061", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040511061" } ] } ], "protein_names": [ { "name": "BRD4 interacting chromatin remodeling complex associated protein", "type": "synonym", "evidence": [ { "id": "A0A8V0YEZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEZ5/entry#names_and_taxonomy" } ] }, { "name": "BRD4-interacting chromatin-remodeling complex-associated protein isoform X2", "type": "synonym", "evidence": [ { "id": "XP_040511061", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040511061" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052569.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040511061", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040511061" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YEZ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEZ5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "BICRA", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEZ5", "locus": { "chromosome": "38", "start_pos": 227650, "end_pos": 207644, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010010800", "url": "https://www.ensembl.org/id/ENSGALG00010010800" } ] } } ], "crossref": [ { "id": "101749950", "url": "https://www.ncbi.nlm.nih.gov/gene/101749950", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR015671", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015671", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052438", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052438", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YAA9", "url": "https://www.orthodb.org/?gene=A0A8V0YAA9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YEY5", "url": "https://www.orthodb.org/?gene=A0A8V0YEY5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YEZ5", "url": "https://www.orthodb.org/?gene=A0A8V0YEZ5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15572", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15572", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15572:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15572:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15249", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15249", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-9933947", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9933947", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_040511061", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040511061", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YAA9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAA9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YAA9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAA9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YEY5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEY5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YEY5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEY5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YEZ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEZ5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YEZ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEZ5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDDEDGRCLLDVICDPQALNDFLHGSEKLHVQESSGNHLTAEQSQPSASVDLDFLEDDILGSPAGGGANLPSSEQPCDILQQSLQEANITEQTLEAEAELDLGSFQLPTLQPVVQAASDGAPQIFSGGADLIGLQQPAVLTHQALVQQSVGADVVNKAISVQPFLQQVGLGNVTIQPISNLQGLPNGSPGGALGIGPIQVVGQQVMAINQPAQQIIAKQVQPSQVATVPVGSYITQTAPEQQQVALTSAGVSPQGAGLVIQKNLPAVATTTLNGSSVFGGVSGAQGSQPLTVTSNLSSPLVQAQNVIIHRTPTPIQPKPAGVLQQKLYQITPKPFGSNNATLTIQNEAALQQQKAQQNLTFMAGKPAQNVVLSGFPQGLPANVFKQPPPQQQALSKPMSVHLLNQGSSIVIPAQHVPQAMLQGQNQFLLPGQLAGAPAVQIPQQLSALPANVGGQILAASHGGGQAHIITSQGPGGQLIANQALPAQILTNQNIAGQLNLGPVLASQNAHGTAHILSAPIQLQPGQVGQPALFQMPVSLAGSLTTQSQPSVAAPLPGAAAAAIGQTGQTVIQGVTLPSQVAMLNAADNLGQAVSIQPSGSSQSPGLLPPQPAPTAGLLPAAAADPPASILAIQPPAAPPAAPAPLQLSVQPPPPAPPPAPLPAASQPSPGLAASPEKIILGQAAAGAVINQDSMQMFLQQVPQGIILQTKQQTPTSQASPALSQFSSQSSSVLVSSQGQPVTVTATPTPAHSHAPTAGPPSSAGGTAPPPSDSKPFSSATAPIAAGKGPTATGKPGATLAMPQPVQTKPGVISSVSGLNLGKGPLQIQVVGKGLSQLVPSVQSQQLYDSKLGSLKKTPTLQPSKEACFLEQLHKHQGAVLHPDYKTSFHSFEDALQRLLPYHVYQGMLPSAQDYRKVDEEFEVVSTQLLKRTQAMLNKYRLLLLEESRRVSPSAEMVMIDRMFIQEEKTMLALDKQLAKEKPDEYVSSSSRSQSLSLAAAQPSSSSSSSSSGLAPAADGSKAAAVQTATAINPTKLVIKHSGGSPSVTWAKASPSLDGDDDALPSRSKPPIKTYEARSRIGLKLKIKQEAGLSKVVHNTALDPVHQPPPVCRVIKAAEQHPAAGQMNGTLEHGSAAPPEKKAAVSFCRLPLRKTYRENVDAFVAEKPTDKGSGAARADKAPLKQEDGTHKGPEGAAADKGRAEESSKLLFFGRGDARPLVLHGSPVPQKSDDPSSGLMKELAEVEEEFYHGMIKTEPPDHGPGAELTWEVPLPPTKRRKSESFEVDNASFSSDSPQDDSLNEHLQSAIDSILNLQQPQTGGQNVRTPSSSYNSSSSPFSSPVHRTDAYLAPNHNGGLGARTLNR", "length": 1364, "header": "tr|A0A8V0YEZ5-1|A0A8V0YEZ5_CHICK Isoform 1 of BRD4 interacting chromatin remodeling complex associated protein OS=Gallus gallus OX=9031 GN=BICRA PE=4 SV=1 CANONICAL=A0A8V0YEZ5-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YAA9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEZ5/entry#A0A8V0YAA9-1", "sequence": { "sequence": "GTDCCSLTPLLPCSDPQALNDFLHGSEKVSNRSSTPTPPQPEIHPLIAESSGNHLTAEQSQPSASVDLDFLEDDILGSPAGGGANLPSSEQPCDILQQSLQEANITEQTLEAEAELDLGSFQLPTLQPVVQAASDGAPQIFSGGADLIGLQQPAVLTHQALVQQSVGADVVNKAISVQPFLQQVGLGNVTIQPISNLQGLPNGSPGGALGIGPIQVVGQQVMAINQPAQQIIAKQQVALTSAGVSPQGAGLVIQKNLPAVATTTLNGSSVFGGVSGAQGSQPLTVTSNLSSPLVQAQNVIIHRTPTPIQPKPAGVLQQKLYQITPKPFGSNNATLTIQNEAALQQQKAQQNLTFMAGKPAQNVVLSGFPQGLPANVFKQPPPQQQALSKPMSVHLLNQGSSIVIPAQHVPQAMLQGQNQFLLPGQLAGAPAVQIPQQLSALPANVGGQILAASHGGGQAHIITSQGPGGQLIANQALPAQILTNQNIAGQLNLGPVLASQNAHGTAHILSAPIQLQPGQTPTSQASPALSQFSSQSSSVLVSSQGQPVTVTATPTPAHSHAPTAGPPSSAGLCQGEVGAVLFGTGRAAGVLHPPSPCSLKAEFSDGAPWGVWVKLCPGSAQLRVCTLLPLPGRRSAVLHRLAASKGAPPGGFPPQSFRGSFPSRAQMVAWSHFSGESGDSTHAAHAELRGSSVLFLSCSFLEQLHKHQGAVLHPDYKTSFHSFEDALQRLLPYHVYQGMLPSAQDYRKVDEEFEVVSTQLLKRTQAMLNKYRLLLLEESRRVSPSAEMVMIDRMFIQEEKTMLALDKQLAKEKPGGQCSPFSLRLYNCVPSRCAPPQRPHGAQGSVSPSLPLPPQFAPGCPRGVPVALEASQDPQVFRRALQSDPCASGRPLGCRGGFPGLPVSCGAPQCVPGAQS", "length": 916, "header": "tr|A0A8V0YAA9-1|A0A8V0YAA9_CHICK Computationally mapped isoform of BRD4 interacting chromatin remodeling complex associated protein OS=Gallus gallus OX=9031 GN=BICRA PE=4 SV=1 CANONICAL=A0A8V0YEZ5-1" }, "locus": { "chromosome": "38", "start_pos": 225256, "end_pos": 214519, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010025845.1", "url": "https://www.ensembl.org/id/ENSGALT00010025845.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010014546.1", "url": "https://www.ensembl.org/id/ENSGALP00010014546.1" } ] } }, { "isoform_ac": "A0A8V0YEY5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEZ5/entry#A0A8V0YEY5-1", "sequence": { "sequence": "ALNDFLHGSEKVSNRSSTPTPPQPEIHPLIAESSGNHLTAEQSQPSASVDLDFLEDDILGSPAGGGANLPSSEQPCDILQQSLQEANITEQTLEAEAELDLGSFQLPTLQPVVQAASDGAPQIFSGGADLIGLQQPAVLTHQALVQQSVGADVVNKAISVQPFLQQVGLGNVTIQPISNLQGLPNGSPGGALGIGPIQVVGQQVMAINQPAQQIIAKQQVALTSAGVSPQGAGLVIQKNLPAVATTTLNGSSVFGGVSGAQGSQPLTVTSNLSSPLVQAQNVIIHRTPTPIQPKPAGVLQQKLYQITPKPFGSNNATLTIQNEAALQQQKAQQNLTFMAGKPAQNVVLSGFPQGLPANVFKQPPPQQQALSKPMSVHLLNQGSSIVIPAQHVPQAMLQGQNQFLLPGQLAGAPAVQIPQQLSALPANVGGQILAASHGGGQAHIITSQGPGGQLIANQALPAQILTNQNIAGQLNLGPVLASQNAHGTAHILSAPIQLQPGQPPKVLDSAPFLLELLLVVSSVGQSRAQIGAGGPEMEDLTQTLGRGAPPVPPSIRWSPPGPPPSASRCPRAPTNAFLHCRSLAVFLPPPPPSPSSPPSSRSFCPITQWDEMLSAPASLTRP", "length": 622, "header": "tr|A0A8V0YEY5-1|A0A8V0YEZ5_CHICK Computationally mapped isoform of BRD4 interacting chromatin remodeling complex associated protein OS=Gallus gallus OX=9031 GN=BICRA PE=4 SV=1 CANONICAL=A0A8V0YEZ5-1" }, "locus": { "chromosome": "38", "start_pos": 219001, "end_pos": 214570, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010025839.1", "url": "https://www.ensembl.org/id/ENSGALT00010025839.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010014544.1", "url": "https://www.ensembl.org/id/ENSGALP00010014544.1" } ] } }, { "isoform_ac": "A0A8V0YEZ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEZ5/entry#A0A8V0YEZ5-1", "sequence": { "sequence": "MDDEDGRCLLDVICDPQALNDFLHGSEKLHVQESSGNHLTAEQSQPSASVDLDFLEDDILGSPAGGGANLPSSEQPCDILQQSLQEANITEQTLEAEAELDLGSFQLPTLQPVVQAASDGAPQIFSGGADLIGLQQPAVLTHQALVQQSVGADVVNKAISVQPFLQQVGLGNVTIQPISNLQGLPNGSPGGALGIGPIQVVGQQVMAINQPAQQIIAKQVQPSQVATVPVGSYITQTAPEQQQVALTSAGVSPQGAGLVIQKNLPAVATTTLNGSSVFGGVSGAQGSQPLTVTSNLSSPLVQAQNVIIHRTPTPIQPKPAGVLQQKLYQITPKPFGSNNATLTIQNEAALQQQKAQQNLTFMAGKPAQNVVLSGFPQGLPANVFKQPPPQQQALSKPMSVHLLNQGSSIVIPAQHVPQAMLQGQNQFLLPGQLAGAPAVQIPQQLSALPANVGGQILAASHGGGQAHIITSQGPGGQLIANQALPAQILTNQNIAGQLNLGPVLASQNAHGTAHILSAPIQLQPGQVGQPALFQMPVSLAGSLTTQSQPSVAAPLPGAAAAAIGQTGQTVIQGVTLPSQVAMLNAADNLGQAVSIQPSGSSQSPGLLPPQPAPTAGLLPAAAADPPASILAIQPPAAPPAAPAPLQLSVQPPPPAPPPAPLPAASQPSPGLAASPEKIILGQAAAGAVINQDSMQMFLQQVPQGIILQTKQQTPTSQASPALSQFSSQSSSVLVSSQGQPVTVTATPTPAHSHAPTAGPPSSAGGTAPPPSDSKPFSSATAPIAAGKGPTATGKPGATLAMPQPVQTKPGVISSVSGLNLGKGPLQIQVVGKGLSQLVPSVQSQQLYDSKLGSLKKTPTLQPSKEACFLEQLHKHQGAVLHPDYKTSFHSFEDALQRLLPYHVYQGMLPSAQDYRKVDEEFEVVSTQLLKRTQAMLNKYRLLLLEESRRVSPSAEMVMIDRMFIQEEKTMLALDKQLAKEKPDEYVSSSSRSQSLSLAAAQPSSSSSSSSSGLAPAADGSKAAAVQTATAINPTKLVIKHSGGSPSVTWAKASPSLDGDDDALPSRSKPPIKTYEARSRIGLKLKIKQEAGLSKVVHNTALDPVHQPPPVCRVIKAAEQHPAAGQMNGTLEHGSAAPPEKKAAVSFCRLPLRKTYRENVDAFVAEKPTDKGSGAARADKAPLKQEDGTHKGPEGAAADKGRAEESSKLLFFGRGDARPLVLHGSPVPQKSDDPSSGLMKELAEVEEEFYHGMIKTEPPDHGPGAELTWEVPLPPTKRRKSESFEVDNASFSSDSPQDDSLNEHLQSAIDSILNLQQPQTGGQNVRTPSSSYNSSSSPFSSPVHRTDAYLAPNHNGGLGARTLNR", "length": 1364, "header": "tr|A0A8V0YEZ5-1|A0A8V0YEZ5_CHICK Isoform 1 of BRD4 interacting chromatin remodeling complex associated protein OS=Gallus gallus OX=9031 GN=BICRA PE=4 SV=1 CANONICAL=A0A8V0YEZ5-1" }, "locus": { "chromosome": "38", "start_pos": 226646, "end_pos": 214386, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010025857.1", "url": "https://www.ensembl.org/id/ENSGALT00010025857.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010014554.1", "url": "https://www.ensembl.org/id/ENSGALP00010014554.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 614, "start_aa": "Thr", "end_pos": 614, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr614", 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YF01-1", "uniprot_ac": "A0A8V0YF01", "uniprot_id": "A0A8V0YF01_CHICK", "mass": { "chemical_mass": 88089.0, "monoisotopic_mass": 88089.0 }, "refseq": { "ac": "XP_015143250", "name": "host cell factor 2 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015143250" }, "gene_names": [ { "name": "HCFC2", "type": "recommended", "evidence": [ { "id": "A0A8V0YF01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF01" } ] }, { "name": "HCFC2", "type": "synonym", "evidence": [ { "id": "XP_015143250", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015143250" } ] } ], "protein_names": [ { "name": "Host cell factor 1", "type": "recommended", "evidence": [ { "id": "A0A8V0YF01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF01/entry#names_and_taxonomy" } ] }, { "name": "C1 factor", "type": "synonym", "evidence": [ { "id": "A0A8V0YF01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF01/entry#names_and_taxonomy" } ] }, { "name": "host cell factor 2 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_015143250", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015143250" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015143250.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015143250", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015143250" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YF01", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF01" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "HCFC2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF01", "locus": { "chromosome": "1", "start_pos": 54704829, "end_pos": 54724934, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010011883", "url": "https://www.ensembl.org/id/ENSGALG00010011883" } ] } } ], "crossref": [ { "id": "A0A8V0YF01", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YF01", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00063", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00063", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "418083", "url": "https://www.ncbi.nlm.nih.gov/gene/418083", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003961", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003961", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015915", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015915", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036116", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036116", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043536", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043536", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR059124", "url": "https://www.ebi.ac.uk/interpro/entry/IPR059124", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y6J2", "url": "https://www.orthodb.org/?gene=A0A8V0Y6J2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y6J6", "url": "https://www.orthodb.org/?gene=A0A8V0Y6J6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YF01", "url": "https://www.orthodb.org/?gene=A0A8V0YF01", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YJQ4", "url": "https://www.orthodb.org/?gene=A0A8V0YJQ4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YJQ9", "url": "https://www.orthodb.org/?gene=A0A8V0YJQ9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46003", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46003", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46003:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46003:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13854", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13854", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-9772755", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9772755", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_015143250", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015143250", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Y6J2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y6J2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y6J2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y6J2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y6J6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y6J6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y6J6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y6J6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YF01", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF01", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YF01-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF01-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJQ4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJQ4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJQ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJQ4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJQ9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJQ9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJQ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJQ9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAAAAGLSWRRVSSFTGPVPRSRHGHRAVAIRELVIIFGGGNEGIADELHVYNTATNQWFLPAVRGDIPPGCAAHGFVCDGTRILVFGGMVEYGRYSNDLYELQASRWLWKKVKPQAPSTGSPPCPRLGHSFSLYGNKCYLFGGLANESEDSNNNVPRYLNDFYELELQHGSGVVGWSIPVTKGIMPSPRESHTAIVYCRKDLGVPKMYIFGGMCGCRLNDLWELDIETMTWSRPETKGTVPLPRSLHTANVIGNKMYVFGGWVPQSAGGEISTHDGEWKCTGSFAYLNLDTTEWIGLISDCQEDKSNLLPGPRAGHCAVAVGTRLYIWSGRDGYRKAWNNQVCCKDLWYLDTEKPPAPSQVQLIRATTNSFQVKWDEVPTVEGYLLQLHADSPVPSAAGTPGTGVPETSVLSSQGGSSLHQSPQSLPSVPCPEMKVDHPSQANNVIPDNVQLSLSSNSLLKIEGKEKVAAPENKITQETMKNHADATGFKESNAPSLLPVCTSSPQTSANVGELHDLEKRTVIPDASVSSTVSSTQTMVTQQAVKTESSSTNGAVVKDETSLTTFNSKSEAAETAYFMPSTKVNTGQANDSHSSRTPQRQMAPVKSRERQWYDVGIFKNSSAVVSQFYLLPEETLNASNKMEDADVPDYRLLKKQDLFPGTVYRFRVAAINGCGVGPFSKVSEFKTCIPGFPGAPSTVKITKSVDCIHLSWEPPASPSGNILEYSAYLAIRSTQLQENPNQLVFMRIYCGLKTSCVVTAAQLSNAHVDYTSRPAIVFRISAKNERGYGPATQVRWLQDMKTSSSK", "length": 807, "header": "tr|A0A8V0YF01-1|A0A8V0YF01_CHICK Isoform 1 of Host cell factor 1 OS=Gallus gallus OX=9031 GN=HCFC2 PE=1 SV=1 CANONICAL=A0A8V0YF01-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Y6J2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF01/entry#A0A8V0Y6J2-1", "sequence": { "sequence": "MGCLRSYSTPCCIRLGNFATNQWFLPAVRGDIPPGCAAHGFVCDGTRILVFGGMVEYGRYSNDLYELQASRWLWKKVKPQAPSTGSPPCPRLGHSFSLYGNKCYLFGGLANESEDSNNNVPRYLNDFYELELQHGSGVVGWSIPVTKGIMPSPRESHTAIVYCRKDLGVPKMYIFGGMCGCRLNDLWELDIETMTWSRPETKGTVPLPRSLHTANVIGNKMYVFGGWVPQSAGGEISTHDGEWKCTGSFAYLNLDTTEWIGLISDCQEDKSNLLPGPRAGHCAVAVGTRLYIWSGRDGYRKAWNNQVCCKDLWYLDTEKPPAPSQVQLIRATTNSFQVKWDEVPTVEGYLLQLHADSPVPSAAGTPGTGVPETSVLSSQGGSSLHQSPQSLPSVPCPEMKVDHPSQANNVIPDNVQLSLSSNSLLKIEGKEKVAAPENKITQETMKNHADATGFKESNAPSLLPVCTSSPQTSANVGELHDLEKRTVIPDASVSSTVSSTQTMVTQQAVKTESSSTNGAVVKDETSLTTFNSKSEAAETAYFMPSTKVNTGQANDSHSSRTPQRQMAPVKSRERQWYDVGIFKNSSAVVSQFYLLPEETLNASNKMEDADVPDYRLLKKQDLFPGTVYRFRVAAINGCGVGPFSKVSEFKTCIPGFPGAPSTVKITKSVDCIHLSWEPPASPSGNILEYSAYLAIRSTQLQENPNQLVFMRIYCGLKTSCVVTAAQLSNAHVDYTSRPAIVFRISAKNERGYGPATQVRWLQDMKTSSSK", "length": 770, "header": "tr|A0A8V0Y6J2-1|A0A8V0Y6J2_CHICK Computationally mapped isoform of Host cell factor C2 OS=Gallus gallus OX=9031 GN=HCFC2 PE=1 SV=1 CANONICAL=A0A8V0YF01-1" }, "locus": { "chromosome": "1", "start_pos": 54724283, "end_pos": 54706908, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028392.1", "url": "https://www.ensembl.org/id/ENSGALT00010028392.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016275.1", "url": "https://www.ensembl.org/id/ENSGALP00010016275.1" } ] } }, { "isoform_ac": "A0A8V0Y6J6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF01/entry#A0A8V0Y6J6-1", "sequence": { "sequence": "MAAAAAGLSWRRVSSFTGPVPRSRHGHRAVAIRELVIIFGGGNEGIADELHVYNTATNQWFLPAVRGDIPPGCAAHGFVCDGTRILVFGGMVEYGRYSNDLYELQASRWLWKKVKPQAPSTGSPPCPRLGHSFSLYGNKCYLFGGLANESEDSNNNVPRYLNDFYELELQHGSGVVGWSIPVTKGIMPSPRESHTAIVYCRKDLGVPKMYIFGGMCGCRLNDLWELDIETMTWSRPETKGTVPLPRSLHTANVIGNKMYVFGGWVPQSAGGEISTHDGEWKCTGSFAYLNLDTTEWIGLISDCQEDKSNLLPGPRAGHCAVAVGTRLYIWSGRDGYRKAWNNQVCCKDLWYLDTEKPPAPSQVQLIRATTNSFQVKWDEVPTVEGYLLQLHADSPVPSAAGTPGTGVPETSVLSSQGGSSLHQSPQSLPSVPCPEMKVDHPSQANNVIPDNVQLSLSSNSLLKIEGKEKVAAPENKITQETMKNHADATGFKESNAPSLLPVCTSSPQTSANVGELHDLEKRTVIPDASVSSTVSSTQTMRTPQRQMAPVKSRERQWYDVGIFKNSSAVVSQFYLLPEETLNASNKMEDADVPDYRLLKKQDLFPGTVYRFRVAAINGCGVGPFSKVSEFKTCIPGFPGAPSTVKITKSVDCIHLSWEPPASPSGNILEYSAYLAIRSTQLQENPNQLVFMRIYCGLKTSCVVTAAQLSNAHVDYTSRPAIVFRISAKNERGYGPATQVRWLQDMKTSSSK", "length": 751, "header": "tr|A0A8V0Y6J6-1|A0A8V0Y6J6_CHICK Computationally mapped isoform of Host cell factor 1 OS=Gallus gallus OX=9031 GN=HCFC2 PE=1 SV=1 CANONICAL=A0A8V0YF01-1" }, "locus": { "chromosome": "1", "start_pos": 54724842, "end_pos": 54706908, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028397.1", "url": "https://www.ensembl.org/id/ENSGALT00010028397.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016280.1", "url": "https://www.ensembl.org/id/ENSGALP00010016280.1" } ] } }, { "isoform_ac": "A0A8V0YF01-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF01/entry#A0A8V0YF01-1", "sequence": { "sequence": "MAAAAAGLSWRRVSSFTGPVPRSRHGHRAVAIRELVIIFGGGNEGIADELHVYNTATNQWFLPAVRGDIPPGCAAHGFVCDGTRILVFGGMVEYGRYSNDLYELQASRWLWKKVKPQAPSTGSPPCPRLGHSFSLYGNKCYLFGGLANESEDSNNNVPRYLNDFYELELQHGSGVVGWSIPVTKGIMPSPRESHTAIVYCRKDLGVPKMYIFGGMCGCRLNDLWELDIETMTWSRPETKGTVPLPRSLHTANVIGNKMYVFGGWVPQSAGGEISTHDGEWKCTGSFAYLNLDTTEWIGLISDCQEDKSNLLPGPRAGHCAVAVGTRLYIWSGRDGYRKAWNNQVCCKDLWYLDTEKPPAPSQVQLIRATTNSFQVKWDEVPTVEGYLLQLHADSPVPSAAGTPGTGVPETSVLSSQGGSSLHQSPQSLPSVPCPEMKVDHPSQANNVIPDNVQLSLSSNSLLKIEGKEKVAAPENKITQETMKNHADATGFKESNAPSLLPVCTSSPQTSANVGELHDLEKRTVIPDASVSSTVSSTQTMVTQQAVKTESSSTNGAVVKDETSLTTFNSKSEAAETAYFMPSTKVNTGQANDSHSSRTPQRQMAPVKSRERQWYDVGIFKNSSAVVSQFYLLPEETLNASNKMEDADVPDYRLLKKQDLFPGTVYRFRVAAINGCGVGPFSKVSEFKTCIPGFPGAPSTVKITKSVDCIHLSWEPPASPSGNILEYSAYLAIRSTQLQENPNQLVFMRIYCGLKTSCVVTAAQLSNAHVDYTSRPAIVFRISAKNERGYGPATQVRWLQDMKTSSSK", "length": 807, "header": "tr|A0A8V0YF01-1|A0A8V0YF01_CHICK Isoform 1 of Host cell factor 1 OS=Gallus gallus OX=9031 GN=HCFC2 PE=1 SV=1 CANONICAL=A0A8V0YF01-1" }, "locus": { "chromosome": "1", "start_pos": 54724842, "end_pos": 54706908, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028402.1", "url": "https://www.ensembl.org/id/ENSGALT00010028402.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016283.1", "url": "https://www.ensembl.org/id/ENSGALP00010016283.1" } ] } }, { "isoform_ac": "A0A8V0YJQ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF01/entry#A0A8V0YJQ4-1", "sequence": { "sequence": "MAAAAAGLSWRRVSSFTGPVPRSRHGHRAVAIRELVIIFGGGNEGIADELHVYNTATNQWFLPAVRGDIPPGCAAHGFVCDGTRILVFGGMVEYGRYSNDLYELQASRWLWKKVKPQAPSTGSPPCPRLGHSFSLYGNKCYLFGGLANESEDSNNNVPRYLNDFYELELQHGSGVVGWSIPVTKGIMPSPRESHTAIVYCRKDLGVPKMYIFGGMCGCRLNDLWELDIETMTWSRPETKGTVPLPRSLHTANVIGNKMYVFGGWVPQSAGGEISTHDGEWKCTGSFAYLNLDTTEWIGLISDCQEDKSNLLPGPRAGHCAVAVGTRLYIWSGRDGYRKAWNNQVCCKDLWYLDTEKPPAPSQVQLIRATTNSFQVKWDEVPTVEGYLLQLHADSPVPSAAGTPGTGVPETSVLSSQGGSSLHQSPQSLPSVPCPEMKVDHPSQANNVIPDNVQLSLSSNSLLKIEGKEKVAAPENKITQETMKNHADATGFKESNAPSLLPVCTSSPQTSANVGELHDLEKRTVIPDASVSSTVSSTQTMMEDADVPDYRLLKKQDLFPGTVYRFRVAAINGCGVGPFSKVSEFKTCIPGFPGAPSTVKITKSVDCIHLSWEPPASPSGNILEYSAYLAIRSTQLQENPNQLVFMRIYCGLKTSCVVTAAQLSNAHVDYTSRPAIVFRISAKNERGYGPATQVRWLQDMKTSSSK", "length": 705, "header": "tr|A0A8V0YJQ4-1|A0A8V0YJQ4_CHICK Computationally mapped isoform of Host cell factor 1 OS=Gallus gallus OX=9031 GN=HCFC2 PE=1 SV=1 CANONICAL=A0A8V0YF01-1" }, "locus": { "chromosome": "1", "start_pos": 54724842, "end_pos": 54706908, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028398.1", "url": "https://www.ensembl.org/id/ENSGALT00010028398.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016281.1", "url": "https://www.ensembl.org/id/ENSGALP00010016281.1" } ] } }, { "isoform_ac": "A0A8V0YJQ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF01/entry#A0A8V0YJQ9-1", "sequence": { "sequence": "MFENVPILWSTSFIYLGISTLYVTSCDTNDDISDFVFLVFKASRWLWKKVKPQAPSTGSPPCPRLGHSFSLYGNKCYLFGGLANESEDSNNNVPRYLNDFYELELQHGSGVVGWSIPVTKGIMPSPRESHTAIVYCRKDLGVPKMYIFGGMCGCRLNDLWELDIETMTWSRPETKGTVPLPRSLHTANVIGNKMYVFGGWVPQSAGGEISTHDGEWKCTGSFAYLNLDTTEWIGLISDCQEDKSNLLPGPRAGHCAVAVGTRLYIWSGRDGYRKAWNNQVCCKDLWYLDTEKPPAPSQVQLIRATTNSFQVKWDEVPTVEGYLLQLHADSPVPSAAGTPGTGVPETSVLSSQGGSSLHQSPQSLPSVPCPEMKVDHPSQANNVIPDNVQLSLSSNSLLKIEGKEKVAAPENKITQETMKNHADATGFKESNAPSLLPVCTSSPQTSANVGELHDLEKRTVIPDASVSSTVSSTQTMVTQQAVKTESSSTNGAVVKDETSLTTFNSKSEAAETAYFMPSTKVNTGQANDSHSSRTPQRQMAPVKSRERQWYDVGIFKNSSAVVSQFYLLPEETLNASNKMEDADVPDYRLLKKQDLFPGTVYRFRVAAINGCGVGPFSKVSEFKTCIPGFPGAPSTVKITKSVDCIHLSWEPPASPSGNILEYSAYLAIRSTQLQENPNQLVFMRIYCGLKTSCVVTAAQLSNAHVDYTSRPAIVFRISAKNERGYGPATQVRWLQDMKTSSSK", "length": 743, "header": "tr|A0A8V0YJQ9-1|A0A8V0YJQ9_CHICK Computationally mapped isoform of Host cell factor C2 OS=Gallus gallus OX=9031 GN=HCFC2 PE=1 SV=1 CANONICAL=A0A8V0YF01-1" }, "locus": { "chromosome": "1", "start_pos": 54722104, "end_pos": 54706908, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028407.1", "url": "https://www.ensembl.org/id/ENSGALT00010028407.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016286.1", "url": "https://www.ensembl.org/id/ENSGALP00010016286.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 402, "start_aa": "Thr", "end_pos": 402, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr402", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "R-GGA-9772755", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9772755", "resource": "Reactome", "description": "Formation of WDR5-containing histone-modifying complexes" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "transcription coactivator activity", "id": "GO:0003713", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003713", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YF01", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF01" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YF01", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF01" } ], "pmid": "" }, { "name": "histone methyltransferase complex", "id": "GO:0035097", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035097", "evidence": [ { "database": "UniProtKB", 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"MSTPSRFKKDKEIIAEYESQVKEIRAQLIEQQKCLEQQTEMRVQLLQDLQDFFRKKSEIEMEYSRNLEKLAERFMAKTRSTKDHQQYKKDQNLLSPVNCWYLLLNQVRRESKDHATLSDIYLNNVIMRFMQISEDSTRMFKKSKEIAFQLHEDLMKVLNELYTVMKTYHMYHAESISAESKLKEAEKQEEKQIGRSGDPVFHIRLEDRHQRRSSVKKIEKMKEKRQAKYSENKLKSIKARNEYLLTLEATNASVFKYYIHDLSDLIDCCDLGYHASLNRALRTYLSAEYNLETSRHEGLDIIENAVDSLEPRSDKQRFMEMFPTAFCPPMKFEFQSHMGDEVCQVTAQQPVQAELMLRYQQLQSRLATLKIENEEVKKTTEATLQTIQDMVTIEDYDVSECFQHSRSTESVKSTVSETYLSKPSIAKRRANQQETEQFYFMKFREYLEGSNLITKLQAKHDLLQRALGEGKYYIIYVNVIPGRRNSHARHQDSGQVIPLIVESCIRFINLYGLQHQGIFRVSGSQVEVNDIKNSFERGENPLADDQSNHDINSVAGVLKLYFRGLENPVFPKERFNDLISCIRIDNLYERALHIRKLLLTLPRSVLIVMRYLFAFLNHLSQYSDENMMDPYNLAICFGPTLMPVPDIQDQVSCQAHVNEIIKTIIIHHEAIFPDAKELDGPVYEKCMAGDDYCDSPYSEHGTLEEVDQDASTEPHTSEDECEPIEAIAKFDYIGRSARELSFKKGASLLLYHRASEDWWEGRHNGIDGLVPHQYIVVQDMDDTFSDTLSQKADSEASSGPITEDKSSSKDMNSPTDRHSDVYLGRQRKRSEPPPPLRRPGRSSDGHCPVHPPHPLSNSSVDLGSPNLATHCSPRTLLQNRNLNADSPERRRRPGHGSLTNISRHDSLKKIDSPPIRRSTSSGQYTGFNDHKPLDPESIAQDIEETMNTALNELRELERQSSAKHAPDVVLDTLEQMKNSPTPATSTESLSPLHSVVLRSSEPQIRRSTSSSSDTMSTFKPMVAPRMGVQLKPPALRPKPIVLPKTNPSIGPSPPSQGPADKSCTM", "length": 1065, "header": "tr|A0A8V0YF03-1|A0A8V0YF03_CHICK Isoform 1 of SLIT-ROBO Rho GTPase-activating protein 1 OS=Gallus gallus OX=9031 GN=SRGAP1 PE=4 SV=1 CANONICAL=A0A8V0YF03-1" }, "locus": { "chromosome": "1", "start_pos": 33705573, "end_pos": 33568058, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029431.1", "url": "https://www.ensembl.org/id/ENSGALT00010029431.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017098.1", "url": "https://www.ensembl.org/id/ENSGALP00010017098.1" } ] } }, { "isoform_ac": "A0A8V0YLW3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF03/entry#A0A8V0YLW3-1", "sequence": { "sequence": "MSTPSRFKKDKEIIAEYESQVKEIRAQLIEQQKCLEQQTEMRVQLLQDLQDFFRKKSEIEMEYSRNLEKLAERFMAKTRSTKDHQQYKKDQNLLSPVNCWYLLLNQVRRESKDHATLSDIYLNNVIMRFMQISEDSTRMFKKSKEIAFQLHEDLMKVLNELYTVMKTYHMYHAESISAESKLKEAEKQEEKQIGRSGDPVFHIRLEDRHQRRSSVKKIEKMKEKRQAKYSENKLKSIKARNEYLLTLEATNASVFKYYIHDLSDLIDCCDLGYHASLNRALRTYLSAEYNLETSRHEGLDIIENAVDSLEPRSDKQRFMEMFPTAFCPPMKFEFQSHMGDEVCQVTAQQPVQAELMLRYQQLQSRLATLKIENEEVKKTTEATLQTIQDMVTIEDYDVSECFQHSRSTESVKSTVSETYLSKPSIAKRRANQQETEQFYFMKFREYLEGSNLITKLQAKHDLLQRALGEGHRAEYMTTRPPNLPPKPQKHRRSRPRSQYSAKLFNGDLESFIKDSGQVIPLIVESCIRFINLYGLQHQGIFRVSGSQVEVNDIKNSFERGIDNLYERALHIRKLLLTLPRSVLIVMRYLFAFLNHLSQYSDENMMDPYNLAICFGPTLMPVPDIQDQVSCQAHVNEIIKTIIIHHEAIFPDAKELDGPVYEKCMAGDDYCDSPYSEHGTLEEVDQDASTEPHTSEDECEPIEAIAKFDYIGRSARELSFKKGASLLLYHRASEDWWEGRHNGIDGLVPHQYIVVQDMDDTFSDTLSQKADSEASSGPITEDKSSSKDMNSPTDRHSDVYLGRQRKRSEPPPPLRRPGRSSDGHCPVHPPHPLSNSSVDLGSPNLATHCSPRTLLQNRNLNADSPERRRRPGHGSLTNISRHDSLKKIDSPPIRRSTSSGQYTGFNDHKPLDPESIAQDIEETMNTALNELRELERQSSAKHAPDVVLDTLEQMKNSPTPATSTESLSPLHSVVLRSSEPQIRRSTSSSSDTMSTFKPMVAPRMGVQLKPPALRPKPIVLPKTNPSIGPSPPSQGPADKSCTM", "length": 1042, "header": "tr|A0A8V0YLW3-1|A0A8V0YLW3_CHICK Computationally mapped isoform of SLIT-ROBO Rho GTPase activating protein 1 OS=Gallus gallus OX=9031 GN=SRGAP1 PE=4 SV=1 CANONICAL=A0A8V0YF03-1" }, "locus": { "chromosome": "1", "start_pos": 33705573, "end_pos": 33568058, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029422.1", "url": "https://www.ensembl.org/id/ENSGALT00010029422.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017092.1", "url": "https://www.ensembl.org/id/ENSGALP00010017092.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 981, "start_aa": "Thr", "end_pos": 981, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr981", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "R-GGA-8980692", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8980692", "resource": "Reactome", "description": "RHOA GTPase cycle" }, { "id": "R-GGA-9013148", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013148", "resource": "Reactome", "description": "CDC42 GTPase cycle" }, { "id": "R-GGA-9013149", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013149", "resource": "Reactome", "description": "RAC1 GTPase cycle" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YF03", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF03" } ], "pmid": "" }, { "name": "small GTPase binding", "id": "GO:0031267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031267", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YF03", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF03" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YF03", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF03" } ], "pmid": "" }, { "name": "nervous system development", "id": "GO:0007399", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007399", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YF03", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF03" } ], "pmid": "" }, { "name": "negative regulation of cell migration", "id": "GO:0030336", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030336", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YF03", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF03" } ], "pmid": "" }, { "name": "regulation of synapse assembly", "id": "GO:0051963", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051963", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YF03", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF03" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 251, "end_pos": 253, "annotation": "n_glycosylation_sequon" }, { "start_pos": 857, "end_pos": 859, "annotation": "n_glycosylation_sequon" }, { "start_pos": 900, "end_pos": 902, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YF03", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF03" }, { "id": "PS51741", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51741" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "F-BAR", "eco_id": "ECO_0000259", "start_pos": 22, "end_pos": 314, "start_aa": "Lys", "end_aa": "Asp", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0YF03", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF03" }, { "id": "PS50238", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50238" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Rho-GAP", "eco_id": "ECO_0000259", "start_pos": 482, "end_pos": 672, "start_aa": "Gly", "end_aa": "Phe", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0YF03", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF03" }, { "id": "PS50002", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50002" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SH3", "eco_id": "ECO_0000259", "start_pos": 721, "end_pos": 780, "start_aa": "Cys", "end_aa": "Met", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 981 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 251, "end_pos": 253 }, { "start_pos": 857, "end_pos": 859 }, { "start_pos": 900, "end_pos": 902 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YF27-1", "uniprot_ac": "A0A8V0YF27", "uniprot_id": "A0A8V0YF27_CHICK", "mass": { "chemical_mass": 71253.0, "monoisotopic_mass": 71253.0 }, "refseq": { "ac": "XP_414596", "name": "sodium-dependent proline transporter isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_414596" }, "gene_names": [ { "name": "SLC6A7", "type": "recommended", "evidence": [ { "id": "A0A8V0YF27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF27" } ] }, { "name": "SLC6A7", "type": "synonym", "evidence": [ { "id": "XP_414596", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_414596" } ] } ], "protein_names": [ { "name": "Transporter", "type": "recommended", "evidence": [ { "id": "A0A8V0YF27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF27/entry#names_and_taxonomy" } ] }, { "name": "sodium-dependent proline transporter isoform X2", "type": "synonym", "evidence": [ { "id": "XP_414596", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_414596" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052544.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_414596.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_414596", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_414596" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YF27", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF27" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SLC6A7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF27", "locus": { "chromosome": "13", "start_pos": 12822359, "end_pos": 12832754, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013654", "url": "https://www.ensembl.org/id/ENSGALG00010013654" } ] } } ], "crossref": [ { "id": "A0A8V0YF27", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YF27", "database": "AlphaFoldDB", "categories": [] }, { "id": "416277", "url": "https://www.ncbi.nlm.nih.gov/gene/416277", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000175", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000175", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037272", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037272", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "RFPTWAE", "url": "https://omabrowser.org/oma/group/RFPTWAE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YF27", "url": "https://www.orthodb.org/?gene=A0A8V0YF27", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YLF5", "url": "https://www.orthodb.org/?gene=A0A8V0YLF5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11616", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11616", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11616:SF231", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11616:SF231", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00209", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00209", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-442660", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-442660", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_414596", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_414596", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YF27", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF27", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YF27-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF27-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLF5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLF5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLF5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLF5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKKIRQQQLCKPVTPELLVSPSSQDGDLGSQCPEDRGNWTGRLDFLLSCIGYCVGLGNVWRFPYRAYTNGGGAFLVPYFIMLAICGIPIFFMELSLGQFSSLGPLAVWKISPLFKGIGMGTILIVSLVAIYYNMIIAYVLFYLFASLTSDLPWQHCGNWWNTELCLDHRVIKAGNTTLPVNISNTVSPSEEYWSRYVLHIQGSSGIGDPGRIRWNLCLCLLLSWTIVYLCILKGVKSSGKVVYFTATFPYLILVMLLIRGVTLEGAWKGIYFYLTPQFDHLLSSKVWIEAALQIFYSLGVGFGGLLTFASYNTFHQNIYRDTFIVTLGNAITSILAGFAIFSVLGYMSQELGVPVNQVAKAGPGLAFVVYPQAMTMLPLSPFWSFLFFFMLLTLGLDSQFAFMETIVTAVTDEFPYYLRPKKAFFSAVICVGLFLMGLILTTEGGMYWLVLLDDYSAGFGLMVVVITTCLVVTRVYGMKRFCRDIHMMLGFQPGPYFRACWMVLSPATMMALLVYNIIKYQPSEYGSYRFPAWAEALGILMGLCSCLMIPAGMLMAVLQEEGTLWERFQQASRPTMDWGPSLEENRTGTYVASLAGSQSPKPLMVHMRKYGGITSYENTAIEVDQEIEEEEEESMM", "length": 636, "header": "tr|A0A8V0YF27-1|A0A8V0YF27_CHICK Isoform 1 of Transporter OS=Gallus gallus OX=9031 GN=SLC6A7 PE=3 SV=1 CANONICAL=A0A8V0YF27-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YF27-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF27/entry#A0A8V0YF27-1", "sequence": { "sequence": "MKKIRQQQLCKPVTPELLVSPSSQDGDLGSQCPEDRGNWTGRLDFLLSCIGYCVGLGNVWRFPYRAYTNGGGAFLVPYFIMLAICGIPIFFMELSLGQFSSLGPLAVWKISPLFKGIGMGTILIVSLVAIYYNMIIAYVLFYLFASLTSDLPWQHCGNWWNTELCLDHRVIKAGNTTLPVNISNTVSPSEEYWSRYVLHIQGSSGIGDPGRIRWNLCLCLLLSWTIVYLCILKGVKSSGKVVYFTATFPYLILVMLLIRGVTLEGAWKGIYFYLTPQFDHLLSSKVWIEAALQIFYSLGVGFGGLLTFASYNTFHQNIYRDTFIVTLGNAITSILAGFAIFSVLGYMSQELGVPVNQVAKAGPGLAFVVYPQAMTMLPLSPFWSFLFFFMLLTLGLDSQFAFMETIVTAVTDEFPYYLRPKKAFFSAVICVGLFLMGLILTTEGGMYWLVLLDDYSAGFGLMVVVITTCLVVTRVYGMKRFCRDIHMMLGFQPGPYFRACWMVLSPATMMALLVYNIIKYQPSEYGSYRFPAWAEALGILMGLCSCLMIPAGMLMAVLQEEGTLWERFQQASRPTMDWGPSLEENRTGTYVASLAGSQSPKPLMVHMRKYGGITSYENTAIEVDQEIEEEEEESMM", "length": 636, "header": "tr|A0A8V0YF27-1|A0A8V0YF27_CHICK Isoform 1 of Transporter OS=Gallus gallus OX=9031 GN=SLC6A7 PE=3 SV=1 CANONICAL=A0A8V0YF27-1" }, "locus": { "chromosome": "13", "start_pos": 12832582, "end_pos": 12822854, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032821.1", "url": "https://www.ensembl.org/id/ENSGALT00010032821.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019438.1", "url": "https://www.ensembl.org/id/ENSGALP00010019438.1" } ] } }, { "isoform_ac": "A0A8V0YLF5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF27/entry#A0A8V0YLF5-1", "sequence": { "sequence": "MKKIRQQQLCKPVTPELLVSPSSQDGDLGSQCPEDRGNWTGRLDFLLSCIGYCVGLGNVWRFPYRAYTNGGGAFLVPYFIMLAICGIPIFFMELSLGQFSSLGPLAVWKISPLFKGIGMGTILIVSLVAIYYNMIIAYVLFYLFASLTSDLPWQHCGNWWNTELCLDHRVIKAGNTTLPVNISNTVSPSEEYWSRYVLHIQGSSGIGDPGRIRWNLCLCLLLSWTIVYLCILKGVKSSGKVVYFTATFPYLILVMLLIRGVTLEGAWKGIYFYLTPQFDHLLSSKVWIEAALQIFYSLGVGFGGLLTFASYNTFHQNIYRDTFIVTLGNAITSILAGFAIFSVLGYMSQELGVPVNQVAKAGPGLAFVVYPQAMTMLPLSPFWSFLFFFMLLTLGLDSQVRTETTRPAAVPGTPGGSGDPLFLPMQFAFMETIVTAVTDEFPYYLRPKKAFFSAVICVGLFLMGLILTTEGGMYWLVLLDDYSAGFGLMVVVITTCLVVTRVYGMKRFCRDIHMMLGFQPGPYFRACWMVLSPATMMALLVYNIIKYQPSEYGSYRFPAWAEALGILMGLCSCLMIPAGMLMAVLQEEGTLWERFQQASRPTMDWGPSLEENRTGTYVASLAGSQSPKPLMVHMRKYGGITSYENTAIEVDQEIEEEEEESMM", "length": 663, "header": "tr|A0A8V0YLF5-1|A0A8V0YLF5_CHICK Computationally mapped isoform of Transporter OS=Gallus gallus OX=9031 GN=SLC6A7 PE=3 SV=1 CANONICAL=A0A8V0YF27-1" }, "locus": { "chromosome": "13", "start_pos": 12832582, "end_pos": 12822854, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032817.1", "url": "https://www.ensembl.org/id/ENSGALT00010032817.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019435.1", "url": "https://www.ensembl.org/id/ENSGALP00010019435.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-442660", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-442660", "resource": "Reactome", "description": "SLC-mediated transport of neurotransmitters" } ], "orthologs": [ { "uniprot_canonical_ac": "Q6PGE7-1", "protein_name": "Sodium-dependent proline transporter", "gene_name": "Slc6a7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKKLQEAHLRKPITPDLLMTPSDQGDVDLDVDFAADRGNWTGKLDFLLSCIGYCVGLGNVWRFPYRAYTNGGGAFLVPYFLMLAICGIPLFFLELSLGQFSSLGPLAVWKISPLFKGAGAAMLLIVGLVAIYYNMIIAYVLFYLFASLTSNLPWEHCGNWWNTELCLEHRGPKSGNGVLPLNLSSTVSPSEEYWSRYVLHIQGSQGIGRPGEIRWNLCLCLLLAWVIVFLCILKGVKSSGKVVYFTATFPYLILLMLLVRGVTLPGAWKGIQFYLTPQFHHLLSSKVWIEAALQIFYSLGVGFGGLLTFASYNTFHQNIYRDTFIVTLGNAITSILAGFAIFSVLGYMSQELGVPVDQVAKAGPGLAFVVYPQAMTMLPLSPFWSFLFFFMLLTLGLDSQFAFLETIVTAVTDEFPYYLRPKKAVFSGLICVAMYLMGLILTTDGGMYWLVLLDDYSASFGLMVVVITTCLAVTRVYGIQRFCRDIHMMLGFKPGLYFRACWLFLSPATLLALLVYSIVKYQPSEYGSYRFPAWAELLGILMGLLSCLMIPAGMLVAVLREEGSLWERLQQASRPAMDWGPSLEENRTGMYVATLAGSQSPKPLMVHMRKYGGITSFENTAIEVDREIAEEEEESMM", "length": 637 }, "evidence": [ { "id": "A0A8V0YF27", "url": "https://omabrowser.org/oma/group/A0A8V0YF27/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q99884-1", "protein_name": "Sodium-dependent proline transporter", "gene_name": "SLC6A7", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKKLQGAHLRKPVTPDLLMTPSDQGDVDLDVDFAAHRGNWTGKLDFLLSCIGYCVGLGNVWRFPYRAYTNGGGAFLVPYFLMLAICGIPLFFLELSLGQFSSLGPLAVWKISPLFKGAGAAMLLIVGLVAIYYNMIIAYVLFYLFASLTSDLPWEHCGNWWNTELCLEHRVSKDGNGALPLNLTCTVSPSEEYWSRYVLHIQGSQGIGSPGEIRWNLCLCLLLAWVIVFLCILKGVKSSGKVVYFTATFPYLILLMLLVRGVTLPGAWKGIQFYLTPQFHHLLSSKVWIEAALQIFYSLGVGFGGLLTFASYNTFHQNIYRDTFIVTLGNAITSILAGFAIFSVLGYMSQELGVPVDQVAKAGPGLAFVVYPQAMTMLPLSPFWSFLFFFMLLTLGLDSQFAFLETIVTAVTDEFPYYLRPKKAVFSGLICVAMYLMGLILTTDGGMYWLVLLDDYSASFGLMVVVITTCLAVTRVYGIQRFCRDIHMMLGFKPGLYFRACWLFLSPATLLALMVYSIVKYQPSEYGSYRFPPWAELLGILMGLLSCLMIPAGMLVAVLREEGSLWERLQQASRPAMDWGPSLEENRTGMYVATLAGSQSPKPLMVHMRKYGGITSFENTAIEVDREIAEEEESMM", "length": 636 }, "evidence": [ { "id": "A0A8V0YF27", "url": "https://omabrowser.org/oma/group/A0A8V0YF27/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YF27", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF27" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YF27", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF27" } ], "pmid": "" }, { "name": "synapse", "id": "GO:0045202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045202", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YF27", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF27" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YF27", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF27" } ], "pmid": "" }, { "name": "symporter activity", "id": "GO:0015293", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015293", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YF27", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF27" } ], "pmid": "" }, { "name": "L-proline transmembrane transporter activity", "id": "GO:0015193", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015193", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YF27", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF27" } ], "pmid": "" }, { "name": "proline:sodium symporter activity", "id": "GO:0005298", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005298", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YF27", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF27" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "proline transport", "id": "GO:0015824", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015824", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YF27", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF27" } ], "pmid": "" }, { "name": "sodium ion transmembrane transport", "id": "GO:0035725", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035725", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YF27", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF27" } ], "pmid": "" }, { "name": "protein catabolic process", "id": "GO:0030163", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030163", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YF27", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF27" } ], "pmid": "" }, { "name": "glycine import across plasma membrane", "id": "GO:1903804", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903804", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YF27", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF27" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 175, "end_pos": 177, "annotation": "n_glycosylation_sequon" }, { "start_pos": 181, "end_pos": 183, "annotation": "n_glycosylation_sequon" }, { "start_pos": 38, "end_pos": 40, "annotation": "n_glycosylation_sequon" }, { "start_pos": 585, "end_pos": 587, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 175, "end_pos": 177 }, { "start_pos": 181, "end_pos": 183 }, { "start_pos": 38, "end_pos": 40 }, { "start_pos": 585, "end_pos": 587 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YF36-1", "uniprot_ac": "A0A8V0YF36", "uniprot_id": "A0A8V0YF36_CHICK", "mass": { "chemical_mass": 57904.0, "monoisotopic_mass": 57904.0 }, "refseq": { "ac": "XP_003643022", "name": "atrial natriuretic peptide receptor 3 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003643022" }, "gene_names": [ { "name": "NPR3", "type": "recommended", "evidence": [ { "id": "A0A8V0YF36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF36" } ] }, { "name": "NPR3", "type": "synonym", "evidence": [ { "id": "XP_003643022", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003643022" } ] } ], "protein_names": [ { "name": "Natriuretic peptide receptor 3", "type": "synonym", "evidence": [ { "id": "A0A8V0YF36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF36/entry#names_and_taxonomy" } ] }, { "name": "atrial natriuretic peptide receptor 3 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_003643022", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003643022" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052572.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_003643022.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003643022", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003643022" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YF36", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF36" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "NPR3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF36", "locus": { "chromosome": "Z", "start_pos": 10589895, "end_pos": 10640719, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013669", "url": "https://www.ensembl.org/id/ENSGALG00010013669" } ] } } ], "crossref": [ { "id": "A0A8V0YF36", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YF36", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd12841", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12841", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "431663", "url": "https://www.ncbi.nlm.nih.gov/gene/431663", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001170", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001170", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001828", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001828", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028082", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028082", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052612", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052612", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:431663", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:431663", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "ETRVMEH", "url": "https://omabrowser.org/oma/group/ETRVMEH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YF36", "url": "https://www.orthodb.org/?gene=A0A8V0YF36", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YTA2", "url": "https://www.orthodb.org/?gene=A0A8V0YTA2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR44755", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR44755", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR44755:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR44755:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01094", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01094", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003643022", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003643022", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YF36", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF36", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YF36-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF36-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YTA2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTA2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YTA2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTA2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPPWLLGSLCCVLAARAALGGGPAGAEAAEEEEKLIRVLVLLPQDDAYLFSLGRVRPAIEYAVRSLRESGSGLPPGYAFQLTYEDSACGNRALFSLVDMVALQRRRPDLLLGPVCEYAAAPVARLAAHWDVPMLSAGALAAGFGAKGGEYSHLTRVAPAYAKMGEMLLALFRHHQWSRATLLYSDSNPERNCYFAMEGVHVVFQDEAFHMAVHSFDETSRHLDIDDVVRALQAGERVVIMCASGDTIRNIMLAAHRQGMTNGDYAFFNIELFNSSSYGNGSWRRGDKHDLEAKKAYSYLQTITLLRTVKPEFEKFSLEVKSSVQKQGLREDDYVNMFVEGFHDAILLYALALQEVLKFGFSKKDGEKIVQQTRNRTYEGIAGQVSIDANGDRYGDFSVIAMTDPEAGTQEVIGDYYGKQGRFEIRSNVKYPWNHGRLRIDESRVSEHTNNTPCKSSGGLGESAVTGIVVGALLGAGLLMAFYFFRKKYRITIERRTQQEDCNMGKHRQLREDSIRSHFSAA", "length": 521, "header": "tr|A0A8V0YF36-1|A0A8V0YF36_CHICK Isoform 1 of Natriuretic peptide receptor 3 OS=Gallus gallus OX=9031 GN=NPR3 PE=4 SV=1 CANONICAL=A0A8V0YF36-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YF36-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF36/entry#A0A8V0YF36-1", "sequence": { "sequence": "MPPWLLGSLCCVLAARAALGGGPAGAEAAEEEEKLIRVLVLLPQDDAYLFSLGRVRPAIEYAVRSLRESGSGLPPGYAFQLTYEDSACGNRALFSLVDMVALQRRRPDLLLGPVCEYAAAPVARLAAHWDVPMLSAGALAAGFGAKGGEYSHLTRVAPAYAKMGEMLLALFRHHQWSRATLLYSDSNPERNCYFAMEGVHVVFQDEAFHMAVHSFDETSRHLDIDDVVRALQAGERVVIMCASGDTIRNIMLAAHRQGMTNGDYAFFNIELFNSSSYGNGSWRRGDKHDLEAKKAYSYLQTITLLRTVKPEFEKFSLEVKSSVQKQGLREDDYVNMFVEGFHDAILLYALALQEVLKFGFSKKDGEKIVQQTRNRTYEGIAGQVSIDANGDRYGDFSVIAMTDPEAGTQEVIGDYYGKQGRFEIRSNVKYPWNHGRLRIDESRVSEHTNNTPCKSSGGLGESAVTGIVVGALLGAGLLMAFYFFRKKYRITIERRTQQEDCNMGKHRQLREDSIRSHFSAA", "length": 521, "header": "tr|A0A8V0YF36-1|A0A8V0YF36_CHICK Isoform 1 of Natriuretic peptide receptor 3 OS=Gallus gallus OX=9031 GN=NPR3 PE=4 SV=1 CANONICAL=A0A8V0YF36-1" }, "locus": { "chromosome": "Z", "start_pos": 10640439, "end_pos": 10599662, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032840.1", "url": "https://www.ensembl.org/id/ENSGALT00010032840.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019449.1", "url": "https://www.ensembl.org/id/ENSGALP00010019449.1" } ] } }, { "isoform_ac": "A0A8V0YTA2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF36/entry#A0A8V0YTA2-1", "sequence": { "sequence": "MPPWLLGSLCCVLAARAALGGGPAGAEAAEEEEKLIRVLVLLPQDDAYLFSLGRVRPAIEYAVRSLRESGSGLPPGYAFQLTYEDSACGNRALFSLVDMVALQRRRPDLLLGPVCEYAAAPVARLAAHWDVPMLSAGALAAGFGAKGGEYSHLTRVAPAYAKMGEMLLALFRHHQWSRATLLYSDSNPERNCYFAMEGVHVVFQDEAFHMAVHSFDETSRHLDIDDVVRALQAGERVVIMCASGDTIRNIMLAAHRQGMTNGDYAFFNIELFNSSSYGNGSWRRGDKHDLEAKKAYSYLQTITLLRTVKPEFEKFSLEVKSSVQKQGLREDDYVNMFVEGFHDAILLYALALQEVLKFGFSKKDGEKIVQQTRNRTYEGIAGQVSIDANGDRYGDFSVIAMTDPEAGTQEVIGDYYGKQGRFEIRSNVKYPWNHGRLRIDESRVSEHTNNTPCKSSGGLGESAVTGIVVGALLGAGLLMAFYFFRALTNLTGRSLIW", "length": 497, "header": "tr|A0A8V0YTA2-1|A0A8V0YTA2_CHICK Computationally mapped isoform of Natriuretic peptide receptor 3 OS=Gallus gallus OX=9031 GN=NPR3 PE=4 SV=1 CANONICAL=A0A8V0YF36-1" }, "locus": { "chromosome": "Z", "start_pos": 10640439, "end_pos": 10589898, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032844.1", "url": "https://www.ensembl.org/id/ENSGALT00010032844.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019450.1", "url": "https://www.ensembl.org/id/ENSGALP00010019450.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:431663", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:431663", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287ALM6-1", "protein_name": "Atrial natriuretic peptide receptor 3", "gene_name": "NPR3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MPSLLVLTFSACVLLDWALLVGCTGGGVGGGPGGGRREREALPPQKIEVLVLLPQDDSYLFSLARVRPAIEYALRSVEGNGTGRRLLPPGTRFQVAYEDSDCGNRALFSLVDRVAAARGAKPDLILGPVCEYAAAPVARLASHWDLPMLSAGALAAGFQHKDTEYSHLTRVAPAYAKMGEMMLALFRHHQWSRAVLVYSDDKLERNCFFTLEGVHEVFQEEGLHTSVYNFDETKGLDLDDIVRYIQANERVVIMCASSDTIRSIMLAAHRHGMTSGDYAFFNIELFNSSSYGDGSWRRGDKHDFEAKQAYSSLQTITLLRTVKPEFEKFSMEVKNSVEKQGLSEEDYVNMFVEGFHDAILLYVLALHEVLRAGYSKKDGGKIIQQTWNRTFEGIAGKVSIDANGDRYGDFSVIAMTDTEAGTQEVIGDYFGKEGRFEMRPNVKYPWGPLKLRIDETRIVEHTNSSPCKASGGLEESAVTGIVVGALLGAGLLMAFYFFRKKYRITIERRNQQEESNIGKHRELREDSIRSHFSVA", "length": 535 }, "evidence": [ { "id": "A0A8V0YF36", "url": "https://omabrowser.org/oma/group/A0A8V0YF36/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A2R8RSJ1-1", "protein_name": "Atrial natriuretic peptide receptor 3 isoform X1", "gene_name": "npr3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSCFMPLCLSIWAVLMVPGRTSALNDNIEVMVMLPRNNTYLFSYTRVFPAIEYAKKALREADAYAGLRFNVRFENSACGMDALYALVDRQKDERPDLVLGPVCEYAASSVTRVASHWNIPVISAGALATGFNSKTPEYSHLTRIAPTYLKMAETFQAIFGHFGWRTAYLIYDDDKDERNCYFTMEGVFTVLSEYHISTDFAVLNSNEERVDPDGIITSVYGSEVVIMCSKADIVRDLMLAAHRRKLTSDSHIFFNIELFNSSSYGDGSWRRRDKYDDEARAAYSFLNTVTLLRSTKPEFEDFSIEMKKSLQQSNIPICEDCSAVNMFMEGFHDALLLYAIALREVKSKGLTKKNGLEITHSMWNRTFEGIAGQVSLDANGDRNGDFSVVRMTDPESGKHETVMNYFGTNGSFQILPGFKREWFSLRTIPPPKPLDPSSGGLGVSAVTGIIVGGILGTALLLAFYFFRKNYRITIERRTLREECDIGKHRQLREDSIRSNFSAA", "length": 503 }, "evidence": [ { "id": "A0A8V0YF36", "url": "https://omabrowser.org/oma/group/A0A8V0YF36/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "P17342-1", "protein_name": "Atrial natriuretic peptide receptor 3", "gene_name": "NPR3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPSLLVLTFSPCVLLGWALLAGGTGGGGVGGGGGGAGIGGGRQEREALPPQKIEVLVLLPQDDSYLFSLTRVRPAIEYALRSVEGNGTGRRLLPPGTRFQVAYEDSDCGNRALFSLVDRVAAARGAKPDLILGPVCEYAAAPVARLASHWDLPMLSAGALAAGFQHKDSEYSHLTRVAPAYAKMGEMMLALFRHHHWSRAALVYSDDKLERNCYFTLEGVHEVFQEEGLHTSIYSFDETKDLDLEDIVRNIQASERVVIMCASSDTIRSIMLVAHRHGMTSGDYAFFNIELFNSSSYGDGSWKRGDKHDFEAKQAYSSLQTVTLLRTVKPEFEKFSMEVKSSVEKQGLNMEDYVNMFVEGFHDAILLYVLALHEVLRAGYSKKDGGKIIQQTWNRTFEGIAGQVSIDANGDRYGDFSVIAMTDVEAGTQEVIGDYFGKEGRFEMRPNVKYPWGPLKLRIDENRIVEHTNSSPCKSSGGLEESAVTGIVVGALLGAGLLMAFYFFRKKYRITIERRTQQEESNLGKHRELREDSIRSHFSVA", "length": 541 }, "evidence": [ { "id": "A0A8V0YF36", "url": "https://omabrowser.org/oma/group/A0A8V0YF36/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P41740-1", "protein_name": "Atrial natriuretic peptide receptor 3", "gene_name": "Npr3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRSLLLFTFSACVLLARALLAGGASSGGGDTGPGNRRREREALAAQKIEVLVLLPRDDSYLFSLARVRPAIEYALRSVEGNGTGRKLLPPGTRFQVAYEDSDCGNRALFSLVDRVAAARGAKPDLILGPVCEYAAAPVARLASHWDLPMLSAGALAAGFQHKDTEYSHLTRVAPAYAKMGEMMLALFRHHHWSRAALLYSDDKLERNCYFTLEGVHEVFQEEGLHTSAYNFDETKDLDLDDIVRYIQGSERVVIMCASGDTIRRIMLAVHRHGMTSGDYAFFNIELFNSSSYGDGSWKRGDKHDFEAKQAYSSLQTVTLLRTAKPEFEKFSMEVKSSVEKQGLNEEDYVNMFVEGFHDAILLYVLALHEVLRAGYSKKDGGKIIQQTWNRTFEGIAGQVSIDANGDRYGDFSVVAMTDTEAGTQEVIGDYFGKEGRFKMRSNVKYPWGSLKLRIDETRIVEHTNSSPCKSCGLEESAVTGIVVGALLGAGLLMAFYFFRKKYRITIERRNHQEESNIGKHRELREDSIRSHFSVA", "length": 535 }, "evidence": [ { "id": "A0A8V0YF36", "url": "https://omabrowser.org/oma/group/A0A8V0YF36/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P70180-1", "protein_name": "Atrial natriuretic peptide receptor 3", "gene_name": "Npr3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRSLLLFTFSACVLLARVLLAGGASSGAGDTRPGSRRRAREALAAQKIEVLVLLPRDDSYLFSLARVRPAIEYALRSVEGNGTGRKLLPPGTRFQVAYEDSDCGNRALFSLVDRVAAARGAKPDLILGPVCEYAAAPVARLASHWDLPMLSAGALAAGFQHKDTEYSHLTRVAPAYAKMGEMMLALFRHHHWSRAALVYSDDKLERNCYFTLEGVHEVFQEEGLHTSAYNFDETKDLDLDDIVRYIQGSERVVIMCASGDTIRRIMLAVHRHGMTSGDYAFFNIELFNSSSYGDGSWRRGDKHDSEAKQAYSSLQTVTLLRTVKPEFEKFSMEVKSSVEKQGLNEEDYVNMFVEGFHDAILLYVLALHEVLRAGYSKKDGGKIIQQTWNRTFEGIAGQVSIDANGDRYGDFSVVAMTDTEAGTQEVIGDYFGKEGRFQMRSNVKYPWGPLKLRLDETRIVEHTNSSPCKSSGGLEESAVTGIVVGALLGAGLLMAFYFFRKKYRITIERRNQQEESNIGKHRELREDSIRSHFSVA", "length": 536 }, "evidence": [ { "id": "A0A8V0YF36", "url": "https://omabrowser.org/oma/group/A0A8V0YF36/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YF36", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF36" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YF36", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF36" } ], "pmid": "" }, { "name": "protein-containing complex", "id": "GO:0032991", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032991", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YF36", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF36" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 6, "go_terms": [ { "name": "protein homodimerization activity", "id": "GO:0042803", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042803", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YF36", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF36" } ], "pmid": "" }, { "name": "chloride ion binding", "id": "GO:0031404", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031404", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YF36", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF36" } ], "pmid": "" }, { "name": "peptide hormone binding", "id": "GO:0017046", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017046", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YF36", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF36" } ], "pmid": "" }, { "name": "natriuretic peptide receptor activity", "id": "GO:0016941", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016941", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YF36", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF36" } ], "pmid": "" }, { "name": "peptide binding", "id": "GO:0042277", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042277", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YF36", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF36" } ], "pmid": "" }, { "name": "receptor decoy activity", "id": "GO:0140319", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140319", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YF36", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF36" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 273, "end_pos": 275, "annotation": "n_glycosylation_sequon" }, { "start_pos": 279, "end_pos": 281, "annotation": "n_glycosylation_sequon" }, { "start_pos": 374, "end_pos": 376, "annotation": "n_glycosylation_sequon" }, { "start_pos": 449, "end_pos": 451, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YF36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF36" }, { "id": "PF01094", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01094" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Receptor ligand binding region", "eco_id": "ECO_0000259", "start_pos": 55, "end_pos": 402, "start_aa": "Val", "end_aa": "Thr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 273, "end_pos": 275 }, { "start_pos": 279, "end_pos": 281 }, { "start_pos": 374, "end_pos": 376 }, { "start_pos": 449, "end_pos": 451 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YF37-1", "uniprot_ac": "A0A8V0YF37", "uniprot_id": "A0A8V0YF37_CHICK", "mass": { "chemical_mass": 176663.0, "monoisotopic_mass": 176663.0 }, "refseq": { "ac": "XP_004942607", "name": "disco-interacting protein 2 homolog A isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004942607" }, "gene_names": [ { "name": "DIP2A", "type": "recommended", "evidence": [ { "id": "A0A8V0YF37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF37" } ] }, { "name": "DIP2A", "type": "synonym", "evidence": [ { "id": "XP_004942607", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004942607" } ] } ], "protein_names": [ { "name": "Disco interacting A", "type": "synonym", "evidence": [ { "id": "A0A8V0YF37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF37/entry#names_and_taxonomy" } ] }, { "name": "disco-interacting protein 2 homolog A isoform X2", "type": "synonym", "evidence": [ { "id": "XP_004942607", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004942607" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052538.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004942607", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004942607" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YF37", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF37" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "DIP2A", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF37", "locus": { "chromosome": "7", "start_pos": 6969244, "end_pos": 7080537, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010010836", "url": "https://www.ensembl.org/id/ENSGALG00010010836" } ] } } ], "crossref": [ { "id": "cd05905", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05905", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "771400", "url": "https://www.ncbi.nlm.nih.gov/gene/771400", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000873", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000873", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR010506", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010506", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR025110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037337", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037337", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042099", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042099", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045851", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045851", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YAH0", "url": "https://www.orthodb.org/?gene=A0A8V0YAH0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YF37", "url": "https://www.orthodb.org/?gene=A0A8V0YF37", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22754", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22754", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22754:SF34", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22754:SF34", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00501", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00501", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF06464", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06464", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23024", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23024", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_004942607", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004942607", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YAH0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAH0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YAH0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAH0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YF37", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF37", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YF37-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF37-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAERGGCSLDAVPLPPEVRESLAELELELSEGDITQKGYEKKRAKLLARYIPLIQGVDPSLQAENRVPGTSQATAVVSKQQKSHSTNSRDERFRSDVHTEAVQAALAKYKERKMPMPSKRRSVLVHSSVETYTPPDTSSASEDEGSLRRQGRITSTRFQSHSNVEPWLNRVIQGSSTSSSASSTSSHPGGKPAAASSTATATAAATVLADLMAHIQLVLGDDIQSKLFHHLSKYRGEAAWILPVTLFEDCGVTLTFFQSLGTILMNNHSAPPDVTTGLLEHLHHERPQVASVRGIPKGYNSSILETGDGVPVNSRVSSKIQQLLNTLKRPKRPPLKEFFVDDFEELLEVQQPDPNQPKPEGNQMNVLKGEPVGVVTNWPPSLLAALQRWGTTQPKAPCLTALDTTGKAVYTLTYGKLWSRSLKLAYTLLNKLTSRNEPLLKPGDRVALVFPNSDPVMFMVAFYGCLLAELIPVPIEVPLTRKDAGSQQIGFLLGSCGVTLALTTDACQKGLPKAQTGEVVTFKGWPRLIWFVIDGKHLAKPTKDWHPQLRDASAEIAYIEYKTSKEGSTVGISVSHASMLAHCHALTQACGYSEAETLTNVLDFKRDAGLWHGVLTSVMNRMHVISIPYALMKVNPLSWIQKVCSYKARVAVVKSRDMHWSLLAQRDQRDVSLSSLRMLIVADGANPWSISSCDAFLNVFQSRGLRPEVICPCASSSEALTVAIRRPPELGGPPPGKAVLSMNCLSYGVIRVDTEEKLSVLTVQDVGQIMPGANVCVVKVDGTPYLCKADEVGEICVNSGATGMAYFGLLGITKNVFEAVPVTASGVPVSDQPFTRTGLLGFVGPDYLVFVVGKLDGLITVSGRRHNADDVVATALAVEPMKFVYRGRIAVFSVTVLHDDRIVLVAEQRPDASEEDSFQWMSRVLQAIDSIHQVGVYCLALVPANTLPKAPLGGIHISETKQRFLEGALHPCNVLMCPHTCVTNLPKPRQKQPDVGPASMIVGNLVAGKRIAQASGRDVTQLEDNDQARKFLYLADVLQWRAQTTPDHPLFLLLNSKGTVASAASCMQLHKRAERVAVALMEKGRLNVGDHVALVYPPGVDLIATFYGCLYAGCIPITVRPPHPQNLATTLPTVKMIVEVSKSACILTTQVITKLLKSKEAAAAVDIKTWPTILDTDDMPKKKLANIFRPTSPDMLAYLDFSVSTTGILAGVKMSHAATSALCRSIKLQCELYPSRQIAICLDPYCGLGFALWCLCSVYSGHQSILVPPLELESNVSLWLSAVSQYKVRVTFCSYSVMEMCTKGLGTQTDMLRMKGVNLSCVRTCMVVAEERPRIALTQSFSKLFKDLGLSARAVSTTFGCRVNVAICLQGTAGPDPTTVYVDMRALRHDRVRLVERGSPHSLPLMESGKILPGVKVIIAHTETKGPLGDSHLGEIWVSSPHNATGYYTVYGEEALHADHFTARLSFGDTQTIWARTGYLGFLRRTELTDASGERHDALYVVGSLDETLELRGMRYHPIDIETSVIRAHKSIAECAVFTWTNLLVVVVELEGSEQEALDLVALVTNVVLEEHYLIVGVVVIVDPGVIPINSRGEKQRMHLRDGFLADQLDPIYVAYNM", "length": 1619, "header": "tr|A0A8V0YF37-1|A0A8V0YF37_CHICK Isoform 1 of Disco interacting A OS=Gallus gallus OX=9031 GN=DIP2A PE=3 SV=1 CANONICAL=A0A8V0YF37-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YAH0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF37/entry#A0A8V0YAH0-1", "sequence": { "sequence": "MAAERGGCSLDAVPLPPEVRESLAELELELSEGDITQKGYEKKRAKLLARYIPLIQGVDPSLQAENRVPGTSQATAVVSKQQKSHSTNSRDERFRSDVHTEAVQAALAKYKERKMPMPSKRRSVLVHSSVETYTPPDTSSASEDEGSLRRQGRITSTRFQSHSNVEPWLNRVIQGSSTSSSASSTSSHPGGKPAAASSTATATAAATVLADLMAHIQLDNHSAPPDVTTGLLEHLHHERPQVASVRGIPKGYNSSILETGDGVPVNSRVSSKIQQLLNTLKRPKRPPLKEFFVDDFEELLEVQQPDPNQPKPEGNQMNVLKGEPVGVVTNWPPSLLAALQRWGTTQPKAPCLTALDTTGKAVYTLTYGKLWSRSLKLAYTLLNKLTSRNEPLLKPGDRVALVFPNSDPVMFMVAFYGCLLAELIPVPIEVPLTRKDAGSQQIGFLLGSCGVTLALTTDACQKGLPKAQTGEVVTFKGWPRLIWFVIDGKHLAKPTKDWHPQLRDASAEIAYIEYKTSKEGSTVGISVSHASMLAHCHALTQACGYSEAETLTNVLDFKRDAGLWHGVLTSVMNRMHVISIPYALMKVNPLSWIQKVCSYKARVAVVKSRDMHWSLLAQRDQRDVSLSSLRMLIVADGANPWSISSCDAFLNVFQSRGLRPEVICPCASSSEALTVAIRRPPELGGPPPGKAVLSMNCLSYGVIRVDTEEKLSVLTVQDVGQIMPGANVCVVKVDGTPYLCKADEVGEICVNSGATGMAYFGLLGITKNVFEAVPVTASGVPVSDQPFTRTGLLGFVGPDYLVFVVGKLDGLITVSGRRHNADDVVATALAVEPMKFVYRGRIAVFSVTVLHDDRIVLVAEQRPDASEEDSFQWMSRVLQAIDSIHQVGVYCLALVPANTLPKAPLGGIHISETKQRFLEGALHPCNVLMCPHTCVTNLPKPRQKQPDVGPASMIVGNLVAGKRIAQASGRDVTQLEDNDQARKFLYLADVLQWRAQTTPDHPLFLLLNSKGTVASAASCMQLHKRAERVAVALMEKGRLNVGDHVALVYPPGVDLIATFYGCLYAGCIPITVRPPHPQNLATTLPTVKMIVEVSKSACILTTQVITKLLKSKEAAAAVDIKTWPTILDTDDMPKKKLANIFRPTSPDMLAYLDFSVSTTGILAGVKMSHAATSALCRSIKLQCELYPSRQIAICLDPYCGLGFALWCLCSVYSGHQSILVPPLELESNVSLWLSAVSQYKVRVTFCSYSVMEMCTKGLGTQTDMLRMKGVNLSCVRTCMVVAEERPRIALTQSFSKLFKDLGLSARAVSTTFGCRVNVAICLQPNRLGKLAEQGTAGPDPTTVYVDMRALRHDRVRLVERGSPHSLPLMESGKILPGVKVIIAHTETKGPLGDSHLGEIWVSSPHNATGYYTVYGEEALHADHFTARLSFGDTQTIWARTGYLGFLRRTELTDASGERHDALYVVGSLDETLELRGMRYHPIDIETSVIRAHKSIAECAVFTWTNLLVVVVELEGSEQEALDLVALVTNVVLEEHYLIVGVVVIVDPGVIPINSRGEKQRMHLRDGFLADQLDPIYVAYNM", "length": 1581, "header": "tr|A0A8V0YAH0-1|A0A8V0YAH0_CHICK Computationally mapped isoform of Disco interacting A OS=Gallus gallus OX=9031 GN=DIP2A PE=3 SV=1 CANONICAL=A0A8V0YF37-1" }, "locus": { "chromosome": "7", "start_pos": 7080504, "end_pos": 6969964, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010025944.1", "url": "https://www.ensembl.org/id/ENSGALT00010025944.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010014607.1", "url": "https://www.ensembl.org/id/ENSGALP00010014607.1" } ] } }, { "isoform_ac": "A0A8V0YF37-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF37/entry#A0A8V0YF37-1", "sequence": { "sequence": "MAAERGGCSLDAVPLPPEVRESLAELELELSEGDITQKGYEKKRAKLLARYIPLIQGVDPSLQAENRVPGTSQATAVVSKQQKSHSTNSRDERFRSDVHTEAVQAALAKYKERKMPMPSKRRSVLVHSSVETYTPPDTSSASEDEGSLRRQGRITSTRFQSHSNVEPWLNRVIQGSSTSSSASSTSSHPGGKPAAASSTATATAAATVLADLMAHIQLVLGDDIQSKLFHHLSKYRGEAAWILPVTLFEDCGVTLTFFQSLGTILMNNHSAPPDVTTGLLEHLHHERPQVASVRGIPKGYNSSILETGDGVPVNSRVSSKIQQLLNTLKRPKRPPLKEFFVDDFEELLEVQQPDPNQPKPEGNQMNVLKGEPVGVVTNWPPSLLAALQRWGTTQPKAPCLTALDTTGKAVYTLTYGKLWSRSLKLAYTLLNKLTSRNEPLLKPGDRVALVFPNSDPVMFMVAFYGCLLAELIPVPIEVPLTRKDAGSQQIGFLLGSCGVTLALTTDACQKGLPKAQTGEVVTFKGWPRLIWFVIDGKHLAKPTKDWHPQLRDASAEIAYIEYKTSKEGSTVGISVSHASMLAHCHALTQACGYSEAETLTNVLDFKRDAGLWHGVLTSVMNRMHVISIPYALMKVNPLSWIQKVCSYKARVAVVKSRDMHWSLLAQRDQRDVSLSSLRMLIVADGANPWSISSCDAFLNVFQSRGLRPEVICPCASSSEALTVAIRRPPELGGPPPGKAVLSMNCLSYGVIRVDTEEKLSVLTVQDVGQIMPGANVCVVKVDGTPYLCKADEVGEICVNSGATGMAYFGLLGITKNVFEAVPVTASGVPVSDQPFTRTGLLGFVGPDYLVFVVGKLDGLITVSGRRHNADDVVATALAVEPMKFVYRGRIAVFSVTVLHDDRIVLVAEQRPDASEEDSFQWMSRVLQAIDSIHQVGVYCLALVPANTLPKAPLGGIHISETKQRFLEGALHPCNVLMCPHTCVTNLPKPRQKQPDVGPASMIVGNLVAGKRIAQASGRDVTQLEDNDQARKFLYLADVLQWRAQTTPDHPLFLLLNSKGTVASAASCMQLHKRAERVAVALMEKGRLNVGDHVALVYPPGVDLIATFYGCLYAGCIPITVRPPHPQNLATTLPTVKMIVEVSKSACILTTQVITKLLKSKEAAAAVDIKTWPTILDTDDMPKKKLANIFRPTSPDMLAYLDFSVSTTGILAGVKMSHAATSALCRSIKLQCELYPSRQIAICLDPYCGLGFALWCLCSVYSGHQSILVPPLELESNVSLWLSAVSQYKVRVTFCSYSVMEMCTKGLGTQTDMLRMKGVNLSCVRTCMVVAEERPRIALTQSFSKLFKDLGLSARAVSTTFGCRVNVAICLQGTAGPDPTTVYVDMRALRHDRVRLVERGSPHSLPLMESGKILPGVKVIIAHTETKGPLGDSHLGEIWVSSPHNATGYYTVYGEEALHADHFTARLSFGDTQTIWARTGYLGFLRRTELTDASGERHDALYVVGSLDETLELRGMRYHPIDIETSVIRAHKSIAECAVFTWTNLLVVVVELEGSEQEALDLVALVTNVVLEEHYLIVGVVVIVDPGVIPINSRGEKQRMHLRDGFLADQLDPIYVAYNM", "length": 1619, "header": "tr|A0A8V0YF37-1|A0A8V0YF37_CHICK Isoform 1 of Disco interacting A OS=Gallus gallus OX=9031 GN=DIP2A PE=3 SV=1 CANONICAL=A0A8V0YF37-1" }, "locus": { "chromosome": "7", "start_pos": 7080504, "end_pos": 6969964, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010025928.1", "url": "https://www.ensembl.org/id/ENSGALT00010025928.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010014595.1", "url": "https://www.ensembl.org/id/ENSGALP00010014595.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YF37", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF37" } ], "pmid": "" }, { "name": "cell surface", "id": "GO:0009986", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009986", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YF37", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF37" } ], "pmid": "" }, { "name": "neuron projection", "id": "GO:0043005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043005", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YF37", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF37" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "nervous system development", "id": "GO:0007399", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007399", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YF37", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF37" } ], "pmid": "" }, { "name": "negative regulation of gene expression", "id": "GO:0010629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010629", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YF37", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF37" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1276, "end_pos": 1278, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1319, "end_pos": 1321, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1444, "end_pos": 1446, "annotation": "n_glycosylation_sequon" }, { "start_pos": 268, "end_pos": 270, "annotation": "n_glycosylation_sequon" }, { "start_pos": 301, "end_pos": 303, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YF37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF37" }, { "id": "PS51912", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51912" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "DMAP1-binding", "eco_id": "ECO_0000259", "start_pos": 11, "end_pos": 129, "start_aa": "Asp", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1276, "end_pos": 1278 }, { "start_pos": 1319, "end_pos": 1321 }, { "start_pos": 1444, "end_pos": 1446 }, { "start_pos": 268, "end_pos": 270 }, { "start_pos": 301, "end_pos": 303 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YF58-1", "uniprot_ac": "A0A8V0YF58", "uniprot_id": "A0A8V0YF58_CHICK", "mass": { "chemical_mass": 15831.0, "monoisotopic_mass": 15831.0 }, "refseq": {}, "gene_names": [ { "name": "GLRX2", "type": "recommended", "evidence": [ { "id": "A0A8V0YF58", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF58" } ] } ], "protein_names": [ { "name": "Glutaredoxin-2, mitochondrial", "type": "recommended", "evidence": [ { "id": "A0A8V0YF58", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF58/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Glutathione-dependent oxidoreductase that facilitates the maintenance of mitochondrial redox homeostasis upon induction of apoptosis by oxidative stress. Involved in response to hydrogen peroxide and regulation of apoptosis caused by oxidative stress. Acts as a very efficient catalyst of monothiol reactions because of its high affinity for protein glutathione-mixed disulfides. Can receive electrons not only from glutathione (GSH), but also from thioredoxin reductase supporting both monothiol and dithiol reactions. Efficiently catalyzes both glutathionylation and deglutathionylation of mitochondrial complex I, which in turn regulates the superoxide production by the complex. Overexpression decreases the susceptibility to apoptosis and prevents loss of cardiolipin and cytochrome c release.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YF58", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF58#function" }, { "database": "UniProtKB", "id": "ARBA00037470", "url": "https://www.uniprot.org/uniprotkb/ARBA00037470#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YF58", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF58" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "GLRX2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF58", "locus": { "chromosome": "8", "start_pos": 3501673, "end_pos": 3499152, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012631", "url": "https://www.ensembl.org/id/ENSGALG00010012631" } ] } } ], "crossref": [ { "id": "A0A8V0YF58", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YF58", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd03419", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03419", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR002109", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002109", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011899", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011899", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014025", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014025", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036249", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036249", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YF58", "url": "https://www.orthodb.org/?gene=A0A8V0YF58", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46679", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46679", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46679:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46679:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00462", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00462", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YF58", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF58", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YF58-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF58-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MFLKRALQLRGRFRMGNRLPASVTLSDAAAVNQIQVLLNVQEIISDNCVVIFSKTTCFYCRMAKKLFEGLNVNYTAVELDVNKNGSQIQDILEQMTGGRTVPRVFVNGSFVGGATDTQRLHEEGKLLPLVHQCQVKTKSGATI", "length": 143, "header": "tr|A0A8V0YF58-1|A0A8V0YF58_CHICK Isoform 1 of Glutaredoxin-2, mitochondrial OS=Gallus gallus OX=9031 GN=GLRX2 PE=3 SV=1 CANONICAL=A0A8V0YF58-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YF58-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF58/entry#A0A8V0YF58-1", "sequence": { "sequence": "MFLKRALQLRGRFRMGNRLPASVTLSDAAAVNQIQVLLNVQEIISDNCVVIFSKTTCFYCRMAKKLFEGLNVNYTAVELDVNKNGSQIQDILEQMTGGRTVPRVFVNGSFVGGATDTQRLHEEGKLLPLVHQCQVKTKSGATI", "length": 143, "header": "tr|A0A8V0YF58-1|A0A8V0YF58_CHICK Isoform 1 of Glutaredoxin-2, mitochondrial OS=Gallus gallus OX=9031 GN=GLRX2 PE=3 SV=1 CANONICAL=A0A8V0YF58-1" }, "locus": { "chromosome": "8", "start_pos": 3501142, "end_pos": 3499188, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030236.1", "url": "https://www.ensembl.org/id/ENSGALT00010030236.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017547.1", "url": "https://www.ensembl.org/id/ENSGALP00010017547.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YF58", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF58" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YF58", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF58" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YF58", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF58" } ], "pmid": "" }, { "name": "2 iron, 2 sulfur cluster binding", "id": "GO:0051537", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051537", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YF58", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF58" } ], "pmid": "" }, { "name": "protein-disulfide reductase activity", "id": "GO:0015035", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015035", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YF58", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF58" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 107, "end_pos": 109, "annotation": "n_glycosylation_sequon" }, { "start_pos": 73, "end_pos": 75, "annotation": "n_glycosylation_sequon" }, { "start_pos": 84, "end_pos": 86, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YF58", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF58" }, { "id": "PF00462", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00462" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Glutaredoxin", "eco_id": "ECO_0000259", "start_pos": 49, "end_pos": 111, "start_aa": "Val", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 107, "end_pos": 109 }, { "start_pos": 73, "end_pos": 75 }, { "start_pos": 84, "end_pos": 86 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YF66-1", "uniprot_ac": "A0A8V0YF66", "uniprot_id": "A0A8V0YF66_CHICK", "mass": { "chemical_mass": 101299.0, "monoisotopic_mass": 101299.0 }, "refseq": { "ac": "XP_015140075", "name": "DNA-binding protein RFX6 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015140075" }, "gene_names": [ { "name": "RFX6", "type": "recommended", "evidence": [ { "id": "A0A8V0YF66", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF66" } ] }, { "name": "RFX6", "type": "synonym", "evidence": [ { "id": "XP_015140075", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015140075" } ] } ], "protein_names": [ { "name": "DNA-binding protein RFX6", "type": "recommended", "evidence": [ { "id": "A0A8V0YF66", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF66/entry#names_and_taxonomy" } ] }, { "name": "DNA-binding protein RFX6 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015140075", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015140075" } ] }, { "name": "Regulatory factor X 6", "type": "synonym", "evidence": [ { "id": "A0A8V0YF66", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF66/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052534.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015140075.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015140075", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015140075" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YF66", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF66" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RFX6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF66", "locus": { "chromosome": "3", "start_pos": 63386429, "end_pos": 63420634, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012330", "url": "https://www.ensembl.org/id/ENSGALG00010012330" } ] } } ], "crossref": [ { "id": "A0A8V0YF66", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YF66", "database": "AlphaFoldDB", "categories": [] }, { "id": "421737", "url": "https://www.ncbi.nlm.nih.gov/gene/421737", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003150", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003150", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036388", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036388", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036390", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036390", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039779", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039779", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057321", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057321", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:421737", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:421737", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "FAKNWEH", "url": "https://omabrowser.org/oma/group/FAKNWEH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YF66", "url": "https://www.orthodb.org/?gene=A0A8V0YF66", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YM32", "url": "https://www.orthodb.org/?gene=A0A8V0YM32", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12619", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12619", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12619:SF28", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12619:SF28", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02257", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02257", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25340", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25340", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015140075", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015140075", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YF66", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF66", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YF66-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF66-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YM32", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM32", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YM32-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM32-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAKGPEQEEAFLHLPATQAMSAAAAPDECYAELLAGDLLPYAEEGLEDGRGLPELPAAIKSEVPFNGETLSSEEEDADTQDGKLRAADKSPSPKKSITQMMKDKKKQTQLTLQWLEENYIVCEGVCLPRCILYAHYLDFCRKEKLEPACAATFGKTIRQKFPLLTTRRLGTRGHSKYHYYGIGIKESSAYYHSVYSGKGLTRFSGSKLKNEGGFTRKYSLSSKTGTLLPEFPSAQHLLLQGCISKDKVDTLIMMYKTHCQCVLDNAINGNFEEIQHFLLHFWQGMPDHLLPLLENPIIVDIFCVCDSILYKVLTDVLIPATMQEMPESLLADIRNFAKNWEQWVVSSLENLPEILMDKKLPIARRFVSSLKRQTSFLHLAQIARPALFDQHVVNSMVSDIEKVDLNSIGSQALLAVSGSTDTDGEVYNEYDSITVFQELKDLLKKNATVESFIEWLDTVVEQRVIKASKQNGRSLKKRAQDFLLKWSFFGARVMHNLTLNNASSFGSFHLIRMLLDEYILLAMETQFNNDKEQELQNLLDKYMKNLDASKATFTASPSSCFLANRNKAASLPSDTSVKNECLVEQTYVSLSASQPSSMPSGLNPFATGDGENMQLTGQMELPQSTGHLMTPPISPALVSRGSVINQGPMAVRPPSVGPVLSTHSQCSSYSEPLYQTLSQTNQNYYGNNSSYQAMFRTQAHSTSGVYHHRAEHGRFNALNEHQFSRDYFNNSCAVTPYSARSPSSYCSSSMTQDAHNMQFLNTGSFNFLSNSAPTCPGATYPPNASNGYYGNNLNYPESHRLGSMVDQHVSVISSVSSIRSLPSYSDTHDPLNILDDSGRKQTGSYYTESSPSIVCRTAMSSNMQTTSSSQCMYGTSGQFTPQENLESHEPPNRGMVSSLPPINTVFMGAAAGGT", "length": 914, "header": "tr|A0A8V0YF66-1|A0A8V0YF66_CHICK Isoform 1 of DNA-binding protein RFX6 OS=Gallus gallus OX=9031 GN=RFX6 PE=4 SV=1 CANONICAL=A0A8V0YF66-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YF66-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF66/entry#A0A8V0YF66-1", "sequence": { "sequence": "MAKGPEQEEAFLHLPATQAMSAAAAPDECYAELLAGDLLPYAEEGLEDGRGLPELPAAIKSEVPFNGETLSSEEEDADTQDGKLRAADKSPSPKKSITQMMKDKKKQTQLTLQWLEENYIVCEGVCLPRCILYAHYLDFCRKEKLEPACAATFGKTIRQKFPLLTTRRLGTRGHSKYHYYGIGIKESSAYYHSVYSGKGLTRFSGSKLKNEGGFTRKYSLSSKTGTLLPEFPSAQHLLLQGCISKDKVDTLIMMYKTHCQCVLDNAINGNFEEIQHFLLHFWQGMPDHLLPLLENPIIVDIFCVCDSILYKVLTDVLIPATMQEMPESLLADIRNFAKNWEQWVVSSLENLPEILMDKKLPIARRFVSSLKRQTSFLHLAQIARPALFDQHVVNSMVSDIEKVDLNSIGSQALLAVSGSTDTDGEVYNEYDSITVFQELKDLLKKNATVESFIEWLDTVVEQRVIKASKQNGRSLKKRAQDFLLKWSFFGARVMHNLTLNNASSFGSFHLIRMLLDEYILLAMETQFNNDKEQELQNLLDKYMKNLDASKATFTASPSSCFLANRNKAASLPSDTSVKNECLVEQTYVSLSASQPSSMPSGLNPFATGDGENMQLTGQMELPQSTGHLMTPPISPALVSRGSVINQGPMAVRPPSVGPVLSTHSQCSSYSEPLYQTLSQTNQNYYGNNSSYQAMFRTQAHSTSGVYHHRAEHGRFNALNEHQFSRDYFNNSCAVTPYSARSPSSYCSSSMTQDAHNMQFLNTGSFNFLSNSAPTCPGATYPPNASNGYYGNNLNYPESHRLGSMVDQHVSVISSVSSIRSLPSYSDTHDPLNILDDSGRKQTGSYYTESSPSIVCRTAMSSNMQTTSSSQCMYGTSGQFTPQENLESHEPPNRGMVSSLPPINTVFMGAAAGGT", "length": 914, "header": "tr|A0A8V0YF66-1|A0A8V0YF66_CHICK Isoform 1 of DNA-binding protein RFX6 OS=Gallus gallus OX=9031 GN=RFX6 PE=4 SV=1 CANONICAL=A0A8V0YF66-1" }, "locus": { "chromosome": "3", "start_pos": 63420458, "end_pos": 63387433, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029519.1", "url": "https://www.ensembl.org/id/ENSGALT00010029519.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017158.1", "url": "https://www.ensembl.org/id/ENSGALP00010017158.1" } ] } }, { "isoform_ac": "A0A8V0YM32-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF66/entry#A0A8V0YM32-1", "sequence": { "sequence": "MAKGPEQEEAFLHLPATQAMSAAAAPDECYAELLAGDLLPYAEEGLEDGRGLPELPAAIKSEVPFNGETLSSEEEDADTQDGKLRAADKSPSPKKSITQMMKDKKKQTQLTLQWLEENYIVCEGVCLPRCILYAHYLDFCRKEKLEPACAATFGKTIRQKFPLLTTRRLGTRGHSKYHYYGIGIKESSAYYHSVYSGKGLTRFSGSKLKNEGGFTRKYSLSSKTGTLLPEFPSAQHLLLQGCISKDKIQHFLLHFWQGMPDHLLPLLENPIIVDIFCVCDSILYKVLTDVLIPATMQEMPESLLADIRNFAKNWEQWVVSSLENLPEILMDKKLPIARRFVSSLKRQTSFLHLAQIARPALFDQHVVNSMVSDIEKVDLNSIGSQALLAVSGSTDTDGEVYNEYDSITVFQELKDLLKKNATVESFIEWLDTVVEQRVIKASKQNGRSLKKRAQDFLLKWSFFGARVMHNLTLNNASSFGSFHLIRMLLDEYILLAMETQFNNDKEQELQNLLDKYMKNLDASKATFTASPSSCFLANRNKAASLPSDTSVKNECLVEQTYVSLSASQPSSMPSGLNPFATGDGENMQLTGQMELPQSTGHLMTPPISPALVSRGSVINQGPMAVRPPSVGPVLSTHSQCSSYSEPLYQTLSQTNQNYYGNNSSYQAMFRTQAHSTSGVYHHRAEHGRFNALNEHQFSRDYFNNSCAVTPYSARSPSSYCSSSMTQDAHNMQFLNTGSFNFLSNSAPTCPGATYPPNASNGYYGNNLNYPESHRLGSMVDQHVSVISSVSSIRSLPSYSDTHDPLNILDDSGRKQTGSYYTESSPSIVCRTAMSSNMQTTSSSQCMYGTSGQFTPQENLESHEPPNRGMVSSLPPINTVFMGAAAGGT", "length": 888, "header": "tr|A0A8V0YM32-1|A0A8V0YM32_CHICK Computationally mapped isoform of DNA-binding protein RFX6 OS=Gallus gallus OX=9031 GN=RFX6 PE=4 SV=1 CANONICAL=A0A8V0YF66-1" }, "locus": { "chromosome": "3", "start_pos": 63420458, "end_pos": 63387433, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029518.1", "url": "https://www.ensembl.org/id/ENSGALT00010029518.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017157.1", "url": "https://www.ensembl.org/id/ENSGALP00010017157.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:421737", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:421737", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6AS29-1", "protein_name": "DNA-binding protein RFX6", "gene_name": "Rfx6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAKVRELEETFVHEQPSPQLPSEIAEECGAQLLGKGLLVYSEESAYLVASARSSEEKDGDLGLQVGVKSEMHLNNGNFSSEEDDADTQESKTKATDPQLSQKKSITQIMKDKKKQTQLTLQWLEDNYIVCEGVCLPRCILYAHYLDFCRKEKLEPACAATFGKTIRQKFPLLTTRRLGTRGHSKYHYYGIGIKESSAYYHSVYSGKGLTRFSGSKLKNEGGFTRKYSLSSKTGTLLPEFPSAQHLVYPGCIAKDKVDTLIMMYKTHCQCILDNAINGNFEEIQHFLLHFWQGMPDHLLPLLENPVIIDIFCVCDSILYKVLTDVLIPATMQEMPESLLADIRNFAKNWEQWVVSSLENLPEALIDKKIPILRRFVSSLKRQTSFLHLAQIARPALFDQHVVNAMVSDIEKVDLNSIGSQALLTISNSTDTESDIYSEYDSITVFQELKDLLKKNATVEAFIEWLDTVVEQRVIKMSKQNGRSLKKRAQDFLLKWSFFGARVMHNLTLNNASSFGSLHLIRMLLDEYILLAMETQFNNDKEQELQNLLDKYMKNSEASKAAFTASPSSCFLANRNKGSSLSSDPVKNESHEETAYVPLPSSQPLAVPHALHSFPAESTETMPLSGQIELSQSTGHLMTPPISPAIASRGSVINQGPMAGRPSSVGTALSAPTHCPTYAEPIYPTLPPANHDFYGTNSNYQTVFRAQSHPASSLYAHRAENGRCMAWTEQQLSRDFFGGSCAGSPYNSRPPSGYGPSPATQESHNMQFLNTGSFNFLSNAGTGSCQGAALPSNSPNGYYGNNINYPEAHRLGSMVNQHVSVISSVRSLPPYSDIHDPLNILDDSGRKQSNLFYAHTSSPVTCRTPVVASNLQTQIPPSSSQCMYGTSGQYPVQDNLDSNGASDREMVSSLPPINTVFMGTAAGGT", "length": 923 }, "evidence": [ { "id": "A0A8V0YF66", "url": "https://omabrowser.org/oma/group/A0A8V0YF66/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E1BFK8-1", "protein_name": "DNA-binding protein RFX6", "gene_name": "RFX6", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAKLPELEDAFLQAQASPPVSPEVQECCVQLLGKGLLVYPEERVYLAAEAQPGRALGSGEKADDPELPGGVKSEMHLSNGNFSSEEEDADNPDSKTKATDPHLSQKKTITQIMKDKKKQTQLTLQWLEENYIVCEGVCLPRCILYAHYLDFCRKEKLEPACAATFGKTIRQKFPLLTTRRLGTRGHSKYHYYGIGIKESSAYYHSVYSGKGLTRFSGSKLKNEGGFTRKYSLSSKTGTLLPEFPSAQHLVYQGCLSKDKVDTLIMMYKTHCQCILDNAINGNFEEIQHFLLHFWQGMPDHLLPLLENPVIIDIFCVCDSILYKVLTDVLIPATMQEMPESLLADIRNFAKNWEQWVVSSLENLPEALTDKKIPIVRRFVSSLKRQTSFLHLAQIARPALFDQHVVNSMVSDIEKVDLNSIGSQALLTISGSTDTESDIYTEYDSITVFQELKDLLKKNATVEAFIEWLDTVVEQRVIKTSKQNGRSLKKRAQDFLLKWSFFGARVMHNLTLNNASSFGSFHLIRMLLDEYILLAMETQFNNDKEQELQNLLDKYMKNSDASKAAFTASPSSCFLANRNKGSTVPSDTVKNESHVETTYLPLSSSQPGGLTSALHLFPAGNTDNMPLPGQMELSQSSGHLMTPPISPAMASRGSVINQGPMAGRPPSVGPVLSAPSHCSAYSEPIYPTFPQASHDFYGTNSNYQTVFRTQPHTPSGLYPHRPEHSRCMVWSDQQLSRDFFSGSCAGSPYNSRPPSSYGPSPHGQDPHSLQFLNTGGFNFLSNAGGASCQGATLPPNSPNGYYGGNVNYPESHRLGSMVNQHVSVISSVRSLPPYGDIHDPLNILDDGSRKQTSSFYADTPPSVACRTPVVASSLQTPIPSSSSQCMYGTSNQYPAQEPLDSHGANGREMVSSLPPINTVFMGTAAGGT", "length": 927 }, "evidence": [ { "id": "A0A8V0YF66", "url": "https://omabrowser.org/oma/group/A0A8V0YF66/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q8C7R7-1", "protein_name": "DNA-binding protein RFX6", "gene_name": "Rfx6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAKVRELEEAFVQEQPSPQLPSEIAEECCAQLLGKGLLVYPEDSAYLLAETAAGARSSGEKGGDPGLQVGVKSEMQLNNGNFSSEEEDADTQESKTKAADPQLSQKKSITQMMKDKKKQTQLTLQWLEDNYIVCEGVCLPRCILYAHYLDFCRKEKLEPACAATFGKTIRQKFPLLTTRRLGTRGHSKYHYYGIGIKESSAYYHSVYSGKGLTRFSGSKLKNEGGFTRKYSLSSKTGTLLPEFPSAQHLVYQGCISKDKVDTLIMMYKTHCQCILDNAINGNFEEIQHFLLHFWQGMPDHLLPLLENPVIIDIFCVCDSILYKVLTDVLIPATMQEMPESLLADIRNFAKNWEQWVVSSLENLPEALIDKKIPILRRFVSSLKRQTSFLHLAQIARPALFDQHVVNAMVSDIEKVDLNSIGSQALLTISNSTDTESDIYSEHDSITVFQELKDLLKKNATVEAFIEWLDTVVEQRVIKMSKQNGRSLKKRAQDFLLKWSFFGARVMHNLTLNNASSFGSFHLIRMLLDEYILLAMETQFNNDKEQELQNLLDKYMKNSDASKAAFTASPSSCFLANRNKASSLASDTVKNESHVETSYVPLPSSQPGAIPPALHPFSTEDTDNMPLPGQIELSQSTGHLMTPPISPAIASRGSVINQGPMASRPPSVGTVLSAPTHCSTYAEPIYPTLSPANHDFYGTNSNYQTMFRTQSHPASSLYAHRAEHGRCMAWTEQQLSRDFFGGSCAGSPYNCRPPSSYGPSTHTQESHSMQVLNTGSFNFLSNAGAGSCQGSTLPSNSPNGYYGNNINYSEAHRLGSMVNQHVSVISSVRSLPPYSDIHDPLNILDDSSRKQNNSFYADTLSPVACRTTVVASNLQTQIPSSSSQCMYGTSNQYPVQDSLDSNAASNREMVSSLPPINTVFMGTAAGDT", "length": 927 }, "evidence": [ { "id": "A0A8V0YF66", "url": "https://omabrowser.org/oma/group/A0A8V0YF66/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8HWS3-1", "protein_name": "DNA-binding protein RFX6", "gene_name": "RFX6", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAKVPELEDTFLQAQPAPQLSPGIQEDCCVQLLGKGLLVYPEETVYLAAEGQPGGEQGGGEKGEDPELPGAVKSEMHLNNGNFSSEEEDADNHDSKTKAADQYLSQKKTITQIVKDKKKQTQLTLQWLEENYIVCEGVCLPRCILYAHYLDFCRKEKLEPACAATFGKTIRQKFPLLTTRRLGTRGHSKYHYYGIGIKESSAYYHSVYSGKGLTRFSGSKLKNEGGFTRKYSLSSKTGTLLPEFPSAQHLVYQGCISKDKVDTLIMMYKTHCQCILDNAINGNFEEIQHFLLHFWQGMPDHLLPLLENPVIIDIFCVCDSILYKVLTDVLIPATMQEMPESLLADIRNFAKNWEQWVVSSLENLPEALTDKKIPIVRRFVSSLKRQTSFLHLAQIARPALFDQHVVNSMVSDIERVDLNSIGSQALLTISGSTDTESGIYTEHDSITVFQELKDLLKKNATVEAFIEWLDTVVEQRVIKTSKQNGRSLKKRAQDFLLKWSFFGARVMHNLTLNNASSFGSFHLIRMLLDEYILLAMETQFNNDKEQELQNLLDKYMKNSDASKAAFTASPSSCFLANRNKGSMVSSDAVKNESHVETTYLPLPSSQPGGLGPALHQFPAGNTDNMPLTGQMELSQIAGHLMTPPISPAMASRGSVINQGPMAGRPPSVGPVLSAPSHCSTYPEPIYPTLPQANHDFYSTSSNYQTVFRAQPHSTSGLYPHHTEHGRCMAWTEQQLSRDFFSGSCAGSPYNSRPPSSYGPSLQAQDSHNMQFLNTGSFNFLSNTGAASCQGATLPPNSPNGYYGSNINYPESHRLGSMVNQHVSVISSIRSLPPYSDIHDPLNILDDSGRKQTSSFYTDTSSPVACRTPVLASSLQTPIPSSSSQCMYGTSNQYPAQETLDSHGTSSREMVSSLPPINTVFMGTAAGGT", "length": 928 }, "evidence": [ { "id": "A0A8V0YF66", "url": "https://omabrowser.org/oma/group/A0A8V0YF66/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YF66", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF66" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 10, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YF66", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF66" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YF66", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF66" } ], "pmid": "" }, { "name": "positive regulation of insulin secretion involved in cellular response to glucose stimulus", "id": "GO:0035774", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035774", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YF66", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF66" } ], "pmid": "" }, { "name": "glucose homeostasis", "id": "GO:0042593", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042593", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YF66", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF66" } ], "pmid": "" }, { "name": "endocrine pancreas development", "id": "GO:0031018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031018", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YF66", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF66" } ], "pmid": "" }, { "name": "pancreatic D cell differentiation", "id": "GO:0003311", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003311", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YF66", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF66" } ], "pmid": "" }, { "name": "pancreatic epsilon cell differentiation", "id": "GO:0090104", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090104", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YF66", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF66" } ], "pmid": "" }, { "name": "type B pancreatic cell differentiation", "id": "GO:0003309", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003309", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YF66", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF66" } ], "pmid": "" }, { "name": "pancreatic A cell differentiation", "id": "GO:0003310", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003310", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YF66", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF66" } ], "pmid": "" }, { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YF66", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF66" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YF66", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF66" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YF66", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF66" } ], "pmid": "" }, { "name": "DNA-binding transcription activator activity, RNA polymerase II-specific", "id": "GO:0001228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001228", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YF66", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF66" } ], "pmid": "" }, { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YF66", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF66" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YF66", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF66" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 446, "end_pos": 448, "annotation": "n_glycosylation_sequon" }, { "start_pos": 496, "end_pos": 498, "annotation": "n_glycosylation_sequon" }, { "start_pos": 501, "end_pos": 503, "annotation": "n_glycosylation_sequon" }, { "start_pos": 687, "end_pos": 689, "annotation": "n_glycosylation_sequon" }, { "start_pos": 688, "end_pos": 690, "annotation": "n_glycosylation_sequon" }, { "start_pos": 729, "end_pos": 731, "annotation": "n_glycosylation_sequon" }, { "start_pos": 783, "end_pos": 785, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YF66", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF66" }, { "id": "PS51526", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51526" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RFX-type winged-helix", "eco_id": "ECO_0000259", "start_pos": 111, "end_pos": 186, "start_aa": "Thr", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 446, "end_pos": 448 }, { "start_pos": 496, "end_pos": 498 }, { "start_pos": 501, "end_pos": 503 }, { "start_pos": 687, "end_pos": 689 }, { "start_pos": 688, "end_pos": 690 }, { "start_pos": 729, "end_pos": 731 }, { "start_pos": 783, "end_pos": 785 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YF77-1", "uniprot_ac": "A0A8V0YF77", "uniprot_id": "A0A8V0YF77_CHICK", "mass": { "chemical_mass": 55061.0, "monoisotopic_mass": 55061.0 }, "refseq": { "ac": "XP_015139975", "name": "Golgi-associated PDZ and coiled-coil motif-containing protein isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015139975" }, "gene_names": [ { "name": "GOPC", "type": "recommended", "evidence": [ { "id": "A0A8V0YF77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF77" } ] }, { "name": "GOPC", "type": "synonym", "evidence": [ { "id": "XP_015139975", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015139975" } ] } ], "protein_names": [ { "name": "Golgi-associated PDZ and coiled-coil motif-containing protein", "type": "recommended", "evidence": [ { "id": "A0A8V0YF77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF77/entry#names_and_taxonomy" } ] }, { "name": "CFTR-associated ligand", "type": "synonym", "evidence": [ { "id": "A0A8V0YF77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF77/entry#names_and_taxonomy" } ] }, { "name": "Golgi-associated PDZ and coiled-coil motif-containing protein isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015139975", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015139975" } ] }, { "name": "PDZ protein interacting specifically with TC10", "type": "synonym", "evidence": [ { "id": "A0A8V0YF77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF77/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052534.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015139975.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015139975", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015139975" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YF77", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF77" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "GOPC", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF77", "locus": { "chromosome": "3", "start_pos": 63101177, "end_pos": 63073010, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012341", "url": "https://www.ensembl.org/id/ENSGALG00010012341" } ] } } ], "crossref": [ { "id": "A0A8V0YF77", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YF77", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd06800", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06800", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd14686", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14686", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "770364", "url": "https://www.ncbi.nlm.nih.gov/gene/770364", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001478", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001478", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036034", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036034", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038879", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038879", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:770364", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:770364", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QCNLRQE", "url": "https://omabrowser.org/oma/group/QCNLRQE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YF77", "url": "https://www.orthodb.org/?gene=A0A8V0YF77", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YM48", "url": "https://www.orthodb.org/?gene=A0A8V0YM48", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16528", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16528", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16528:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16528:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00595", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00595", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-5627083", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5627083", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9013406", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013406", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_015139975", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015139975", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YF77", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF77", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YF77-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF77-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YM48", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM48", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YM48-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM48-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRAGTFRSPGCVAAPGEPGPPRGRRGTAEAGGSASRALCEARPGRAVAGGMSAAGGVGSCGPGGAACGGGVGGAASAPGGGVSMFRWLEVLEKEFDKAFVDVDLLLGEIDPDQADITYEGRQKMTSLSSCFAQLCHKAQTVSQINHKLEAQLVDLKSELTETQAEKAVLEKEVHDQLLQLHAVQLQLHAQTGQNVDSGAIKAKLSVLSVDELERELEANKKEKVKEAQLEAEVKLLRKENEALRRHIAVLQAEVYGARLAAKYLDKELAGRVQQIQLLGRDMKGPAHDKLWNQLEAEIHLHRHKTVIRACRGRNDLKRPMQAPPGHDPDALKKSQGVGPIRKVLLVKEDHEGLGISITGGKEHGVPILISEIHPGQPADRCGGLHVGDAILAVNGVNLRDAKHKEAVTILSQQRGEIEFEVVYVAPEVDSDDENVEYEDESGHRYRLYLDELEEGANSGSNRKEVNVDVKPSQVFDKKPSIDGHENGDLGNSVEPSLEDAAPKLTRSAESLS", "length": 512, "header": "tr|A0A8V0YF77-1|A0A8V0YF77_CHICK Isoform 1 of Golgi-associated PDZ and coiled-coil motif-containing protein OS=Gallus gallus OX=9031 GN=GOPC PE=1 SV=1 CANONICAL=A0A8V0YF77-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YF77-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF77/entry#A0A8V0YF77-1", "sequence": { "sequence": "MRAGTFRSPGCVAAPGEPGPPRGRRGTAEAGGSASRALCEARPGRAVAGGMSAAGGVGSCGPGGAACGGGVGGAASAPGGGVSMFRWLEVLEKEFDKAFVDVDLLLGEIDPDQADITYEGRQKMTSLSSCFAQLCHKAQTVSQINHKLEAQLVDLKSELTETQAEKAVLEKEVHDQLLQLHAVQLQLHAQTGQNVDSGAIKAKLSVLSVDELERELEANKKEKVKEAQLEAEVKLLRKENEALRRHIAVLQAEVYGARLAAKYLDKELAGRVQQIQLLGRDMKGPAHDKLWNQLEAEIHLHRHKTVIRACRGRNDLKRPMQAPPGHDPDALKKSQGVGPIRKVLLVKEDHEGLGISITGGKEHGVPILISEIHPGQPADRCGGLHVGDAILAVNGVNLRDAKHKEAVTILSQQRGEIEFEVVYVAPEVDSDDENVEYEDESGHRYRLYLDELEEGANSGSNRKEVNVDVKPSQVFDKKPSIDGHENGDLGNSVEPSLEDAAPKLTRSAESLS", "length": 512, "header": "tr|A0A8V0YF77-1|A0A8V0YF77_CHICK Isoform 1 of Golgi-associated PDZ and coiled-coil motif-containing protein OS=Gallus gallus OX=9031 GN=GOPC PE=1 SV=1 CANONICAL=A0A8V0YF77-1" }, "locus": { "chromosome": "3", "start_pos": 63097809, "end_pos": 63073011, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029537.1", "url": "https://www.ensembl.org/id/ENSGALT00010029537.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017169.1", "url": "https://www.ensembl.org/id/ENSGALP00010017169.1" } ] } }, { "isoform_ac": "A0A8V0YM48-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF77/entry#A0A8V0YM48-1", "sequence": { "sequence": "MRAGTFRSPGCVAAPGEPGPPRGRRGTAEAGGSASRALCEARPGRAVAGGMSAAGGVGSCGPGGAACGGGVGGAASAPGGGVSMFRWLEVLEKEFDKAFVDVDLLLGEIDPDQADITYEGRQKMTSLSSCFAQLCHKAQTVSQINHKLEAQLVDLKSELTETQAEKAVLEKEVHDQLLQLHAVQLQLHAQTGQNVDSGAIKAKLERELEANKKEKVKEAQLEAEVKLLRKENEALRRHIAVLQAEVYGARLAAKYLDKELAGRVQQIQLLGRDMKGPAHDKLWNQLEAEIHLHRHKTVIRACRGRNDLKRPMQAPPGHDPDALKKSQGVGPIRKVLLVKEDHEGLGISITGGKEHGVPILISEIHPGQPADRCGGLHVGDAILAVNGVNLRDAKHKEAVTILSQQRGEIEFEVVYVAPEVDSDDENVEYEDESGHRYRLYLDELEEGANSGSNRKEVNVDVKPSQVFDKKPSIDGHENGDLGNSVEPSLEDAAPKLTRSAESLS", "length": 504, "header": "tr|A0A8V0YM48-1|A0A8V0YM48_CHICK Computationally mapped isoform of Golgi-associated PDZ and coiled-coil motif-containing protein OS=Gallus gallus OX=9031 GN=GOPC PE=1 SV=1 CANONICAL=A0A8V0YF77-1" }, "locus": { "chromosome": "3", "start_pos": 63097809, "end_pos": 63073011, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029542.1", "url": "https://www.ensembl.org/id/ENSGALT00010029542.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017173.1", "url": "https://www.ensembl.org/id/ENSGALP00010017173.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:770364", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:770364", "resource": "KEGG Pathway" }, { "id": "R-GGA-5627083", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5627083", "resource": "Reactome", "description": "RHO GTPases regulate CFTR trafficking" }, { "id": "R-GGA-9013406", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013406", "resource": "Reactome", "description": "RHOQ GTPase cycle" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287A6H2-1", "protein_name": "Golgi-associated PDZ and coiled-coil motif-containing protein", "gene_name": "GOPC", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSAGGPCPAGAGGGPGGASCAVGVPPGGVSMFRWLEVLEKEFDKAFVDVDLLLGEIDPDQADITYEGRQKMTSLSSCFAQLCHKAQTVSQINHKLEAQLVDLKSELTETQAEKVVLEKEVHDQLLQLHSIQLQLHAKTGQSVDSGTIKAKLSVPSVEELERELEANKKEKMKEAQLEAEVKLLRKENEALRRHIAVLQAEVYGARLAAKYLDKELAGRVQQIQLLGRDMKGPAHDKLWNQLEAEIHLHRHKTVIRACRGRNDLKRPMHAPPGHDQDSLKKSQGVGPIRKVLLLKEDHEGLGISITGGKEHGVPILISEIHPGQPADRCGGLHVGDAILAVNGVNLRDTKHKEAVTILSQQRGEIEFEVVYVAPEVDSDDENVEYEDESGHRYRLYLDELEGSTNPGASCKDASGEIKVLQGFNKKAVTDGHENGDLGTSSETPLEDSASKLDDLHSLYHKKSY", "length": 463 }, "evidence": [ { "id": "A0A8V0YF77", "url": "https://omabrowser.org/oma/group/A0A8V0YF77/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8I5ZTW6-1", "protein_name": "Golgi-associated PDZ and coiled-coil motif-containing protein", "gene_name": "Gopc", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSAGGPCPAGAGSGPGGASCPVGVSPGGVSMFRWLEVLEKEFDKAFVDVDLLLGEIDPDQADITYEGRQKMTSLSSCFAQLCHKAQTVSQINHKLEAQLVDLRSELTETQAEKVVLEKEVHDQLLQLHSTQLQLHAKTGQSVDSGAIKAKLVSKAGSALERELEANKTEKVKEARLEAEVKLLRKENEALRRHIAVLQAEVYGARLAAKYLDKELAGRVQQIQLLGRDMKGPAHDKLWNQLEAEIHLHRHKTVIRACRGRQDLKRPMQAPPGHDQDSLKKSQGVGPIRKVLLLKEDHEGLGISITGGKEHGVPILISEIHPGQPADRCGGLHVGDAVLAVNGVNLRDTKHKEAVTILSQQRGEIEFEVVYVAPEVDSDDENVEYEDESGHRYRLYLDELEGGGNSGASCKDSSGEMKVLQGYNKKTVRDAHENGDVGASGESPLDDTAVRAAHPHSLHQKKAY", "length": 463 }, "evidence": [ { "id": "A0A8V0YF77", "url": "https://omabrowser.org/oma/group/A0A8V0YF77/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E1BAX1-1", "protein_name": "Golgi-associated PDZ and coiled-coil motif-containing protein", "gene_name": "GOPC", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSAGGPCPAGAGGGSGGASCAVGVSPGGVSMFRWLEVLEKEFDKAFVDVDLLLGEIDPDQADITYEGRQKMTSLSSCFAQLCHKAQTVSQINHKLEAQLVDLKSELTETQAEKVVLEKEVHDQLLQLHSIQLQLHAKTGQSVDSGTIKAKLSVPSVEELERELEANKKEKMKEAQLEAEVKLLRKENEALRRHIAVLQAEVYGARLAAKYLDKELAGRVQQIQLLGRDMKGPAHDKLWNQLEAEIHLHRHKTVIRACRGRNDLKRPMHAPPGHDQDSLKKSQGVGPIRKVLLLKEDHEGLGISITGGKEHGVPILISEIHPGQPADRCGGLHVGDAILAVNGVNLRDTKHKEAVTILSQQRGEIEFEVVYVAPEVDSDDENVEYEDESGHRYRLYLDELEGSSNPGASCKDTSGEIKMLQGFNKKAVTDGHENGDLGASSETPLEDNASKLDDLHSLYHKKSY", "length": 463 }, "evidence": [ { "id": "A0A8V0YF77", "url": "https://omabrowser.org/oma/group/A0A8V0YF77/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q8BH60-1", "protein_name": "Golgi-associated PDZ and coiled-coil motif-containing protein", "gene_name": "Gopc", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAGGPCPAGAGGGPGGSSCPVGVSPGGVSMFRWLEVLEKEFDKAFVDVDLLLGEIDPDQADITYEGRQKMTSLSSCFAQLCHKAQTVSQINHKLEAQLVDLRSELTETQAEKVVLEKEVHEQLLQLHSTQLQLHAKTGQSVDSGAIKAKLSVHSVEDLERELEANKTEKVKEARLEAEVKLLRKENEALRRHIAVLQAEVYGARLAAKYLDKELAGRVQQIQLLGRDMKGPAHDKLWNQLEAEIHLHRHKTVIRACRGRNDLKRPMQAPPGHDQDSLKKSQGVGPIRKVLLLKEDHEGLGISITGGKEHGVPILISEIHPGQPADRCGGLHVGDAILAVNGVNLRDTKHKEAVTILSQQRGEIEFEVVYVAPEVDSDDENVEYEDESGHRYRLYLDELEGSGNSGASCKDSSGEMKMLQGYNKKAVRDAHENGDVGAAGESPLDDTAARAAHLHSLHQKKAY", "length": 463 }, "evidence": [ { "id": "A0A8V0YF77", "url": "https://omabrowser.org/oma/group/A0A8V0YF77/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9HD26-1", "protein_name": "Golgi-associated PDZ and coiled-coil motif-containing protein", "gene_name": "GOPC", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSAGGPCPAAAGGGPGGASCSVGAPGGVSMFRWLEVLEKEFDKAFVDVDLLLGEIDPDQADITYEGRQKMTSLSSCFAQLCHKAQSVSQINHKLEAQLVDLKSELTETQAEKVVLEKEVHDQLLQLHSIQLQLHAKTGQSADSGTIKAKLSGPSVEELERELEANKKEKMKEAQLEAEVKLLRKENEALRRHIAVLQAEVYGARLAAKYLDKELAGRVQQIQLLGRDMKGPAHDKLWNQLEAEIHLHRHKTVIRACRGRNDLKRPMQAPPGHDQDSLKKSQGVGPIRKVLLLKEDHEGLGISITGGKEHGVPILISEIHPGQPADRCGGLHVGDAILAVNGVNLRDTKHKEAVTILSQQRGEIEFEVVYVAPEVDSDDENVEYEDESGHRYRLYLDELEGGGNPGASCKDTSGEIKVLQGFNKKAVTDTHENGDLGTASETPLDDGASKLDDLHTLYHKKSY", "length": 462 }, "evidence": [ { "id": "A0A8V0YF77", "url": "https://omabrowser.org/oma/group/A0A8V0YF77/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 8, "go_terms": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YF77", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF77" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YF77", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF77" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YF77", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF77" } ], "pmid": "" }, { "name": "postsynaptic density", "id": "GO:0014069", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0014069", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YF77", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF77" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YF77", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF77" } ], "pmid": "" }, { "name": "dendrite", "id": "GO:0030425", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030425", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YF77", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF77" } ], "pmid": "" }, { "name": "trans-Golgi network transport vesicle", "id": "GO:0030140", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030140", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YF77", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF77" } ], "pmid": "" }, { "name": "protein-containing complex", "id": "GO:0032991", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032991", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YF77", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF77" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YF77", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF77" } ], "pmid": "" }, { "name": "negative regulation of protein localization to cell surface", "id": "GO:2000009", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000009", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YF77", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF77" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YF77", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF77" } ], "pmid": "" }, { "name": "transmembrane transporter binding", "id": "GO:0044325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044325", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YF77", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF77" } ], "pmid": "" }, { "name": "molecular sequestering activity", "id": "GO:0140313", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140313", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YF77", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF77" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YF77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF77" }, { "id": "PS50106", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50106" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PDZ", "eco_id": "ECO_0000259", "start_pos": 342, "end_pos": 425, "start_aa": "Lys", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YF84-1", "uniprot_ac": "A0A8V0YF84", "uniprot_id": "A0A8V0YF84_CHICK", "mass": { "chemical_mass": 84187.0, "monoisotopic_mass": 84187.0 }, "refseq": {}, "gene_names": [ { "name": "RRP1B", "type": "recommended", "evidence": [ { "id": "A0A8V0YF84", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF84" } ] } ], "protein_names": [ { "name": "Ribosomal RNA processing 1B", "type": "synonym", "evidence": [ { "id": "A0A8V0YF84", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF84/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YF84", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF84" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RRP1B", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF84", "locus": { "chromosome": "1", "start_pos": 110132879, "end_pos": 110110661, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010011925", "url": "https://www.ensembl.org/id/ENSGALG00010011925" } ] } } ], "crossref": [ { "id": "A0A8V0YF84", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YF84", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR010301", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010301", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PPALYCK", "url": "https://omabrowser.org/oma/group/PPALYCK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YF84", "url": "https://www.orthodb.org/?gene=A0A8V0YF84", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YJZ1", "url": "https://www.orthodb.org/?gene=A0A8V0YJZ1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13026", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13026", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13026:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13026:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05997", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05997", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YF84", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF84", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YF84-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF84-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJZ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJZ1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJZ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJZ1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAPAAAQAPEIQFAQRLAANEKRIRDRAVKKLRGYISLRTQRPGGGFSQEELLKIWKGLFYCMWMQDKPLLQEELANNISQLIHVIQNTEAQHLFIRTFWQTMSREWNGIDNLRLDKYYMLIRMILRQSFEVLKRNDWDESLRELLLQLLMKEVMDPDSNAPKGIKFHFIDIYLQELAKVGAKELTADQSLKFIEPFCNFVAQSKDPSVMHAVASGIFEIIVDQSPYAIEDLMKELESSGDEEDVSEDDEQGKKEMLKTKASRRLSGKSAQSAEKTEDVDENADDSIGPVLQFDYKAVADKLFELASKKNTPALNRKRLYKLVKKFQDLAEGIFPQDFPEDVSTDEDDDTFSRGRRKKKVVKPSGKNSLEKVKGSGKDEQEASSAKETSVPQKKRKKRKIRESPHADSGTTDGNSEEGIAETSGSVILNPGKMPDNKMKKKKKLLVNETNEIRNAVSDTGDKHSVSAQSSQADTEQSKKIQSEKMNPKVQNVLGKLECQNGPANAKKAEDVNTSLTPLIPKVGKKKQKAGSALVNGENFSQQTDLKCNKEGPLSRDVDSESEPSRKVKLKKKTKLVALEGIEVSNQKAATLKKKRKVKEVLNSVEANGILETACKKSKKEESSTALSPLKKKKAKQGSDFVKFEKSTVPKALLFRKARSTISSTRASIPLNKLQSSGSKKVTFGLNKNMTAEFKKTDKSILVSPEGPSRVAFNPAQKPRHGVLKSPAGTPDGEPKLKKPLTAQAKKKTTARAFF", "length": 754, "header": "tr|A0A8V0YF84-1|A0A8V0YF84_CHICK Isoform 1 of Ribosomal RNA processing 1B OS=Gallus gallus OX=9031 GN=RRP1B PE=1 SV=1 CANONICAL=A0A8V0YF84-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YF84-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF84/entry#A0A8V0YF84-1", "sequence": { "sequence": "MAPAAAQAPEIQFAQRLAANEKRIRDRAVKKLRGYISLRTQRPGGGFSQEELLKIWKGLFYCMWMQDKPLLQEELANNISQLIHVIQNTEAQHLFIRTFWQTMSREWNGIDNLRLDKYYMLIRMILRQSFEVLKRNDWDESLRELLLQLLMKEVMDPDSNAPKGIKFHFIDIYLQELAKVGAKELTADQSLKFIEPFCNFVAQSKDPSVMHAVASGIFEIIVDQSPYAIEDLMKELESSGDEEDVSEDDEQGKKEMLKTKASRRLSGKSAQSAEKTEDVDENADDSIGPVLQFDYKAVADKLFELASKKNTPALNRKRLYKLVKKFQDLAEGIFPQDFPEDVSTDEDDDTFSRGRRKKKVVKPSGKNSLEKVKGSGKDEQEASSAKETSVPQKKRKKRKIRESPHADSGTTDGNSEEGIAETSGSVILNPGKMPDNKMKKKKKLLVNETNEIRNAVSDTGDKHSVSAQSSQADTEQSKKIQSEKMNPKVQNVLGKLECQNGPANAKKAEDVNTSLTPLIPKVGKKKQKAGSALVNGENFSQQTDLKCNKEGPLSRDVDSESEPSRKVKLKKKTKLVALEGIEVSNQKAATLKKKRKVKEVLNSVEANGILETACKKSKKEESSTALSPLKKKKAKQGSDFVKFEKSTVPKALLFRKARSTISSTRASIPLNKLQSSGSKKVTFGLNKNMTAEFKKTDKSILVSPEGPSRVAFNPAQKPRHGVLKSPAGTPDGEPKLKKPLTAQAKKKTTARAFF", "length": 754, "header": "tr|A0A8V0YF84-1|A0A8V0YF84_CHICK Isoform 1 of Ribosomal RNA processing 1B OS=Gallus gallus OX=9031 GN=RRP1B PE=1 SV=1 CANONICAL=A0A8V0YF84-1" }, "locus": { "chromosome": "1", "start_pos": 110130105, "end_pos": 110110725, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028533.1", "url": "https://www.ensembl.org/id/ENSGALT00010028533.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016376.1", "url": "https://www.ensembl.org/id/ENSGALP00010016376.1" } ] } }, { "isoform_ac": "A0A8V0YJZ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF84/entry#A0A8V0YJZ1-1", "sequence": { "sequence": "MAPAAAQAPEIQFAQRLAANEKRIRDRAVKKLRGYISLRTQRPGGGFSQEELLKIWKGLFYCMWMQDKPLLQEELANNISQLIHVIQNTEAQHLFIRTFWQTMSREWNGIDNLRLDKYYMLIRMILRQSFEVLKRNDWDESLRELLLQLLMKEVMDPDSNAPKGIKFHFIDIYLQELAKVGAKELTADQSLKFIEPFCNFVAQSKDPSVMHAVASGIFEIIVDQSPYAIEDLMKELESSGDEEDVSEDDEQGKKEMLKTKASRRLSGKSAQSAEKTEDVDENADDSIGPVLQFDYKAVADKLFELASKKNTPALNRKRIFPQDFPEDVSTDEDDDTFSRGRRKKKVVKPSGKNSLEKVKGSGKDEQEASSAKETSVPQKKRKKRKIRESPHADSGTTDGNSEEGIAETSGSVILNPGKMPDNKMKKKKKLLVNETNEIRNAVSDTGDKHSVSAQSSQADTEQSKKIQSEKMNPKVQNVLGKLECQNGPANAKKAEDVNTSLTPLIPKVGKKKQKAGSALVNGENFSQQTDLKCNKEGPLSRDVDSESEPSRKVKLKKKTKLVALEGIEVSNQKAATLKKKRKVKEVLNSVEANGILETACKKSKKEESSTALSPLKKKKAKQGSDFVKFEKSTVPKALLFRKARSTISSTRASIPLIDESSSCISFNSLACFSTEFKKTDKSILVSPEGPSRVAFNPAQKPRHGVLKSPAGTPDGEPKLKKPLTAQAKKKTTARAFF", "length": 737, "header": "tr|A0A8V0YJZ1-1|A0A8V0YJZ1_CHICK Computationally mapped isoform of Ribosomal RNA processing 1B OS=Gallus gallus OX=9031 GN=RRP1B PE=1 SV=1 CANONICAL=A0A8V0YF84-1" }, "locus": { "chromosome": "1", "start_pos": 110130105, "end_pos": 110110725, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028531.1", "url": "https://www.ensembl.org/id/ENSGALT00010028531.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016374.1", "url": "https://www.ensembl.org/id/ENSGALP00010016374.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0ABK0LB97-1", "protein_name": "Ribosomal RNA processing 1B", "gene_name": "Rrp1b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAPAMQSTELQFAQRLASSEKGVRDRAVRKLRQYLSARTQSDTGSFSQEELLKIWKGLFYCMWVQDEPLLQEELANIISQLIHVVNSSEAQHLFIQTFWQTVNREWQGIDKLRLDKYYMLIRLVLRQSFEVLKRNAWEESQITLFLDILMKEILSPESRSPNGVRSHLIDVYLDELSTVGGRELLADQNLKLIDPFCRIAAKTKEPQTKASPDYTRSCSDEGKKAEVLVPVNSATSWLPIQDALPHQTLSFCLSCGTCHTLVQTVAKGVFEVIVDQSAFVPEESVEEQKTKEDGNGLPANELACQKVVGGKKTALDECLRDGVIGSRERDICAALKDSGSPLQFDYKAVADRLLEIANSKSTPPFNRKRLCRLVRKFQDLSEGNGAQLSFAEDISAGENGQALSQRRHKRKRKKLLERAALEREEGNTVSAAGEEDGGGHIHKRKRKKRKRSHFQSDTQDLGSVAEAAVPSADSEPGAAQRHALQACVAAPTAEATSNTRENSSEPTPATPIHSKRKRQRKKNLRAHREIWKSTTLPQEDVSKNDPASGQPQTALISSSEGGQARKRKRKLGALPVSSGDLTVQKAGTPASPVEGNDGQTTLPRCKRSQKKTASNTLDHYDPSSQKTAISKKRKKMKQTSNGVLECSAGQIQALGSNRTLKKPLKMEDDLVKFDTRFLPKALFFRKAKNSSATRPQGPTVQLNKTPSSSKKVTFGLNRNMTAEFKKTDKSILVSPTGLSRVAFNPEQRPLHGVLKTPTSSPASTPLSTMKLPATTPKRRPRAADFF", "length": 786 }, "evidence": [ { "id": "A0A8V0YF84", "url": "https://omabrowser.org/oma/group/A0A8V0YF84/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "I3L5I1-1", "protein_name": "Ribosomal RNA processing 1B", "gene_name": "RRP1B", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAPAMQPAEIQFAQRLASHEKGIRDRAVKKLRQYISVKTQRETGGFSQEELLKIWKGLFYCMWVQDEPLLQEELASAISQLVHVVNNSEAQHLFLQTFWQTVTREWTGIDRRRLDKLCMLTRLVLRQSFEVLKRSGWEESQIQLFLDVLMKEVLHPESQAPSGVKFHFVAIYLEELSRVGGKELLADQNLKFIDPFCKVAARAKDHALVQTIARGVFEVIVDQSPLVPEGTLGVQKAREGDSDLSEEETSESDMAWRRAAGKKPPAPGGPQSRKEGVGDGGRDDAGSSEDAGPLLQFDYRAVAERLREVATSKDVPPFNRKRLSRLIRKFRDLSEGRIPRLSFAEDAPAAPDDRALSRGRRKRKASKLRGDAEVGREQGTKSFPAEEEEAEGGLRKRKRKRKKRNHLRPAHLGPGGEAVCPEQNGSREPEAGPGKAQQTSAAELGAGAAPSLSRRKRLRKRSLRAQVQSPESAASPPEDAAPGGPASGPTQGVALAGGAPVLKKQRKLGALLVNGSGPPTRAWPPQEGPPARPADGGGCPAAVPQSGELGRKKGEPGGLDLRPPCARKAAVLKKRKKVSQMSPLAAHRGLKLVQALGGAGILRPLRKELRTEKDFVKFEAAFSPKPLFFRKAKSSTTAPPGTPPQPNRTPSSAKKVTFGLSRNMTAGPVTAPGAGGCRTEAPAVEWGLRLPPGRVQEDRQEPLGQSHGPLPRGLQPRAEAAARGAEDAHQLAGRRAPGDQAAADSHAKEKAHGDGLLLG", "length": 759 }, "evidence": [ { "id": "A0A8V0YF84", "url": "https://omabrowser.org/oma/group/A0A8V0YF84/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q14684-1", "protein_name": "Ribosomal RNA processing protein 1 homolog B", "gene_name": "RRP1B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAPAMQPAEIQFAQRLASSEKGIRDRAVKKLRQYISVKTQRETGGFSQEELLKIWKGLFYCMWVQDEPLLQEELANTIAQLVHAVNNSAAQHLFIQTFWQTMNREWKGIDRLRLDKYYMLIRLVLRQSFEVLKRNGWEESRIKVFLDVLMKEVLCPESQSPNGVRFHFIDIYLDELSKVGGKELLADQNLKFIDPFCKIAAKTKDHTLVQTIARGVFEAIVDQSPFVPEETMEEQKTKVGDGDLSAEEIPENEVSLRRAVSKKKTALGKNHSRKDGLSDERGRDDCGTFEDTGPLLQFDYKAVADRLLEMTSRKNTPHFNRKRLSKLIKKFQDLSEGSSISQLSFAEDISADEDDQILSQGKHKKKGNKLLEKTNLEKEKGSRVFCVEEEDSESSLQKRRRKKKKKHHLQPENPGPGGAAPSLEQNRGREPEASGLKALKARVAEPGAEATSSTGEESGSEHPPAVPMHNKRKRPRKKSPRAHREMLESAVLPPEDMSQSGPSGSHPQGPRGSPTGGAQLLKRKRKLGVVPVNGSGLSTPAWPPLQQEGPPTGPAEGANSHTTLPQRRRLQKKKAGPGSLELCGLPSQKTASLKKRKKMRVMSNLVEHNGVLESEAGQPQALGSSGTCSSLKKQKLRAESDFVKFDTPFLPKPLFFRRAKSSTATHPPGPAVQLNKTPSSSKKVTFGLNRNMTAEFKKTDKSILVSPTGPSRVAFDPEQKPLHGVLKTPTSSPASSPLVAKKPLTTTPRRRPRAMDFF", "length": 758 }, "evidence": [ { "id": "A0A8V0YF84", "url": "https://omabrowser.org/oma/group/A0A8V0YF84/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q91YK2-1", "protein_name": "Ribosomal RNA processing protein 1 homolog B", "gene_name": "Rrp1b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALAMQSSEFQFAQRLASSEKGVRDRAVRKLRQYLSARTQSDTGSFSQEELLKIWKGLFYCMWVQDEPLLQEELANIISQLIHVVNSLEAQYLFIQTFWQTMNREWQGIDKLQLDKYYMLIRLVLRQSFEVLKRNAWEESQITLFLDILMKEILSPESQSPNGVRTHLIDVYLEELTTVGGAELLADQNLKLIDPFCRIAAKTKDHTLVQTVARGVFEVIVDQSACVPQESVEERKTKEDGSGFPTKALACRKAVSGKKAALDECLRDGVIGSRERDICAALKDSGSPLQFDYKAVADRLLEIANSKSTPPFNRKRLCRLVRKFQDLCEGNGAPLSSAEDNGQRRHKRKRKKLLESEKGDTVSPAAEEDSGGHIHKKKRKKRKRSHFQPDTQNLDAVAVPKVPDSESEPDTAQRQAPCGQACVTEPTAEAVSSIGENSSKPTPVMPIHNKRKRPRKKKLRAHKEICKSTTLPQEDMSKNDAVSGHSQSSAAHISSSEGVQAQKRKRKLGALPDSSSDLPVQKSGTPTSPVEGKDGQTTLPRCKRSQKKTASSTLDPCDPSSQKPAISKKKKKTMKLMSNGVLESNPGQIQALGSNRTLKKPLKTEDDFVKFDTRFLPKPLFFRKAKNSSATRPQGPAGQLNKTPSSSKKVTFGLNRNMTAEFKKTDKSILVSPTGLSRVAFNPEQRPLHGVLKTATSSPASTPLSPMRLPATTPKRRPRAADFF", "length": 724 }, "evidence": [ { "id": "A0A8V0YF84", "url": "https://omabrowser.org/oma/group/A0A8V0YF84/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "transcription coactivator activity", "id": "GO:0003713", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003713", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YF84", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF84" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YF84", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF84" } ], "pmid": "" }, { "name": "chromosome", "id": "GO:0005694", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005694", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YF84", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF84" } ], "pmid": "" }, { "name": "preribosome, small subunit precursor", "id": "GO:0030688", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030688", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YF84", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF84" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YF84", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF84" } ], "pmid": "" }, { "name": "rRNA processing", "id": "GO:0006364", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006364", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YF84", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF84" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 447, "end_pos": 449, "annotation": "n_glycosylation_sequon" }, { "start_pos": 512, "end_pos": 514, "annotation": "n_glycosylation_sequon" }, { "start_pos": 538, "end_pos": 540, "annotation": "n_glycosylation_sequon" }, { "start_pos": 688, "end_pos": 690, "annotation": "n_glycosylation_sequon" }, { "start_pos": 78, "end_pos": 80, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 447, "end_pos": 449 }, { "start_pos": 512, "end_pos": 514 }, { "start_pos": 538, "end_pos": 540 }, { "start_pos": 688, "end_pos": 690 }, { "start_pos": 78, "end_pos": 80 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": 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"count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YF85-1", "uniprot_ac": "A0A8V0YF85", "uniprot_id": "A0A8V0YF85_CHICK", "mass": { "chemical_mass": 60494.0, "monoisotopic_mass": 60494.0 }, "refseq": { "ac": "XP_004943188", "name": "60 kDa SS-A/Ro ribonucleoprotein isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004943188" }, "gene_names": [ { "name": "TROVE2", "type": "recommended", "evidence": [ { "id": "A0A8V0YF85", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF85" } ] }, { "name": "TROVE2", "type": "synonym", "evidence": [ { "id": "XP_004943188", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004943188" } ] } ], "protein_names": [ { "name": "RNA-binding protein RO60", "type": "recommended", "evidence": [ { "id": "A0A8V0YF85", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF85/entry#names_and_taxonomy" } ] }, { "name": "60 kDa SS-A/Ro ribonucleoprotein isoform X1", "type": "synonym", "evidence": [ { "id": "XP_004943188", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004943188" } ] }, { "name": "60 kDa SS-A/Ro ribonucleoprotein", "type": "synonym", "evidence": [ { "id": "A0A8V0YF85", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF85/entry#names_and_taxonomy" } ] }, { "name": "TROVE domain family member 2", "type": "synonym", "evidence": [ { "id": "A0A8V0YF85", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF85/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052539.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_004943188.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004943188", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004943188" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YF85", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF85" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TROVE2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF85", "locus": {} } ], "crossref": [ { "id": "A0A8V0YF85", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YF85", "database": "AlphaFoldDB", "categories": [] }, { "id": "424358", "url": "https://www.ncbi.nlm.nih.gov/gene/424358", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR008858", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008858", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036465", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036465", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037214", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037214", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040322", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040322", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056800", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056800", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:424358", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424358", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WWYEWLK", "url": "https://omabrowser.org/oma/group/WWYEWLK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YF85", "url": "https://www.orthodb.org/?gene=A0A8V0YF85", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YIE6", "url": "https://www.orthodb.org/?gene=A0A8V0YIE6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14202", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14202", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14202:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14202:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05731", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05731", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25045", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25045", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_004943188", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004943188", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YF85", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF85", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YF85-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF85-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YIE6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIE6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YIE6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIE6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MMEDEANQVQPLNEMQVPNSDSDYVWHVTDMNRLHRFLCFGSEGGTYCVKEQRLGFESAAALMRLVEEGRGCEVVQEIKTFSQEGRTAKQEPLLFALAICSQCSDAKTKQAAFKAVPEVCCVPTHLFTFIQFKKDLKEGMKCGMWGRALRKAVADWYNGKNGMAVALAVTKYKQRSGWSHKDLLRLSHLKPASEGVAIVTKYITKGWKDVQEAYKDKAVSAETEKLLKYLEAVDRVKHTKDELEVIHLIEEYGLVREHLLTNHLKSKEVWKALLKDMPISVLLRNLGKMTANSVLEPRSSEVAIVCERLRNEKLLKKGRIHPFHVWVALETYKSGHGSRGKLWWRPDEDILEALDASFYKTFETVEPTGKRFVVAVDVSASMTQKVLGSVLNANTVAAIMCMVVARTEKDSHIVAFSHELVPCPVTADMTLPQVLVKMYEIPMGTTDCSLPMIWAQKTQTAADVFIVFTDNETFAGNTRPATALREYREKMGIPAKLIVCGMTSNGFTIADPDDRGMLDICGFDAGALDVIRNFILDLI", "length": 539, "header": "tr|A0A8V0YF85-1|A0A8V0YF85_CHICK Isoform 1 of RNA-binding protein RO60 OS=Gallus gallus OX=9031 GN=TROVE2 PE=1 SV=1 CANONICAL=A0A8V0YF85-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YF85-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF85/entry#A0A8V0YF85-1", "sequence": { "sequence": "MMEDEANQVQPLNEMQVPNSDSDYVWHVTDMNRLHRFLCFGSEGGTYCVKEQRLGFESAAALMRLVEEGRGCEVVQEIKTFSQEGRTAKQEPLLFALAICSQCSDAKTKQAAFKAVPEVCCVPTHLFTFIQFKKDLKEGMKCGMWGRALRKAVADWYNGKNGMAVALAVTKYKQRSGWSHKDLLRLSHLKPASEGVAIVTKYITKGWKDVQEAYKDKAVSAETEKLLKYLEAVDRVKHTKDELEVIHLIEEYGLVREHLLTNHLKSKEVWKALLKDMPISVLLRNLGKMTANSVLEPRSSEVAIVCERLRNEKLLKKGRIHPFHVWVALETYKSGHGSRGKLWWRPDEDILEALDASFYKTFETVEPTGKRFVVAVDVSASMTQKVLGSVLNANTVAAIMCMVVARTEKDSHIVAFSHELVPCPVTADMTLPQVLVKMYEIPMGTTDCSLPMIWAQKTQTAADVFIVFTDNETFAGNTRPATALREYREKMGIPAKLIVCGMTSNGFTIADPDDRGMLDICGFDAGALDVIRNFILDLI", "length": 539, "header": "tr|A0A8V0YF85-1|A0A8V0YF85_CHICK Isoform 1 of RNA-binding protein RO60 OS=Gallus gallus OX=9031 GN=TROVE2 PE=1 SV=1 CANONICAL=A0A8V0YF85-1" }, "locus": { "chromosome": "8", "start_pos": 3515035, "end_pos": 3508721, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030299.1", "url": "https://www.ensembl.org/id/ENSGALT00010030299.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017572.1", "url": "https://www.ensembl.org/id/ENSGALP00010017572.1" } ] } }, { "isoform_ac": "A0A8V0YIE6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF85/entry#A0A8V0YIE6-1", "sequence": { "sequence": "MMEDEANQVQPLNEMQVPNSDSDYVWHVTDMNRLHRFLCFGSEGGTYCVKEQRLGFESAAALMRLVEEGRGCEVVQEIKTFSQEGRTAKQEPLLFALAICSQCSDAKTKQAAFKAVPEVCCVPTHLFTFIQFKKDLKEGMKCGMWGRALRKAVADWYNGKNGMAVALAVTKYKQRSGWSHKDLLRLSHLKPASEGVAIVTKYITKGWKDVQEAYKDKAVSAETEKLLKYLEAVDRVKHTKDELEVIHLIEEYGLVREHLLTNHLKSKEVWKALLKDMPISVLLRNLGKMTANSVLEPRSSEVAIVCERLRNEKLLKKGRIHPFHVWVALETYKSGHGSRGKLWWRPDEDILEALDASFYKTFETVEPTGKRFVVAVDVSASMTQKVLGSVLNANTVAAIMCMVVARTEKDSHIVAFSHELVPCPVTADMTLPQVLVKMYEIPMGTTDCSLPMIWAQKTQTAADVFIVFTDNETFAGNTRPATALREYREKMGIPAKLIVCGMTSNGFTIADPDDRGLQKSIIWHT", "length": 525, "header": "tr|A0A8V0YIE6-1|A0A8V0YIE6_CHICK Computationally mapped isoform of RNA-binding protein RO60 OS=Gallus gallus OX=9031 GN=TROVE2 PE=1 SV=1 CANONICAL=A0A8V0YF85-1" }, "locus": { "chromosome": "8", "start_pos": 3515035, "end_pos": 3508195, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030302.1", "url": "https://www.ensembl.org/id/ENSGALT00010030302.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017576.1", "url": "https://www.ensembl.org/id/ENSGALP00010017576.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:424358", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424358", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287B6J4-1", "protein_name": "RNA-binding protein RO60", "gene_name": "RO60", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEESVSQMQPMHETQLANSEGGYVWQVTDMNRLHRFLCFGSEGGTYYIQEQRLGLQNAEALLRLIEDGRGCEVIQEIKSFSQEGRNAKQEPTLFALAICSQCSDTSTKQAAFKAVPEVCRIPTHLFTFIQFKKDLKESMHCGMWGRALRKAVADWYNEKGGMALALAVTKYKQRNGWSHKDLLRLSHLKPSSEGLAIVTKYITKGWKEVHDTYKEKALSVETERLLKYLEAVEKVKRTRDELEVIHLIEEHRLVREHLLTNHLKSKEVWKALLQEMPLTALLRNLGKMTANSVLEPGNSEVSLVCEKLCNEKLLKKARIHPFHVLVALETYKTGHGLRGKLKWRPDEEILQALDAAFYKTFKMVEPTGKRFLLAVDVSGSMEQRVLGSILSASTVAAAMCMVVTRTESDSYIVAFSDEMVPCPLTTDMTLQQVLMAMSQIPAGETDCSLPMIWAQKTNTAADVFIVFTDNETFAGSVHPAAALREYRKKMGIPAKLIVCGMASNGFTIADPDDRGMLDMCGFDTGALDVIRNFTLDVI", "length": 538 }, "evidence": [ { "id": "A0A8V0YF85", "url": "https://omabrowser.org/oma/group/A0A8V0YF85/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A3L7HK29-1", "protein_name": "RNA-binding protein RO60", "gene_name": "Ro60", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MEESANQLQPLSESQVANSEGGYVWQVTDMNRLHRFLCFGSEGGTYYIKEQKLGLENAEALIRLIEDGRGCEVIQEIKSFSQEGRTAKQEPLLFALAICSQCSDIKTKQAAFKAVPEVCRIPTHLFTFIQFKKDLKQSMKCGMWGRALRKAVADWYNEKGGMAIALAVTKYKQRNGWSHKDLLRLSHLKPSSEGLAVVTKYITKGWKEVHELYREKALSVETEKLLKYLEAVEKVKRTKDELEVIHLIEEHQLVREHLLTNHLKSKEVWKALLQEMPLTALLRNLGKMTANSVLEPGNSEVSLVCEKLCNEKLLKKARIHPFHVLIALETYRTGHGLRGKLKWTPDKEILQALDTAFYKTFKTVEPTGKRFLLAVDVSASMNQRVLGNILNASTVAAAMCMVVTRTEKESSIVAFACDMVPFPVTTDMTLQQVLTAMNKVPAGSTDCSLPMIWAQKTNTAADVFIVFTDNETYAGQVHPAVALREYRKKMNIPAKLIVCGMTSNGFTIADPDDRGMLDMCGFDTSALDVIRNFTLDVI", "length": 538 }, "evidence": [ { "id": "A0A8V0YF85", "url": "https://omabrowser.org/oma/group/A0A8V0YF85/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "D3ZRN5-1", "protein_name": "RNA-binding protein RO60", "gene_name": "Ro60", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEESANQLQPLSDNQVANSEGGYVWQVTDMNRLHRFLCFGSEGGTCYIKEQKLGLENAEALIRLIEDGRGSEVIQEIKSFSQEGRTAKQEPLLFALAICSQCADVSTKQAAFKAVPEVCRIPTHLFTFIQFKKDLKESMKCGMWGRALRKAVADWYNEKGGMAVALAVTKYKQRNGWSHKDLLRLSHLKPNSEGLAIVTKYITKGWKEVHEQYKEKPLSVETDKLLKYLEAVEKVKRTKDDLEVTHLIEEHQLVREQLLTSHLKSKEVWKALLQEMPLTALLRNLGKMTANSVLEPGSSEVSLVCEKLSNEKLLKKARIHPFHVLTALETYRTGHGLRGKLKWIPDKEILQALDAAFYKTFKTVEPTGKRFLLAVDVSGSMDQRVLGSVLNASTVAAAMCMVVTRTEKESSVVAFACDMVPFPVTTDMTLQQVLTAMNKVPAGTTDCSLPMIWAQKTGTAADVFIVFTDNETFAGQVHPAIALREYRKKMAIPAKLLVCGMTSNGFTIADPDDRGMLDMCGFDTAALDVIRNFTLDVI", "length": 538 }, "evidence": [ { "id": "A0A8V0YF85", "url": "https://omabrowser.org/oma/group/A0A8V0YF85/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1MIZ7-1", "protein_name": "RNA-binding protein RO60", "gene_name": "RO60", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGAPGVETGDFQVVKWRPGRRVRASEPSPGASNPGDTFLSLRGGSQIATETRLAGTEALPFPRLSPTSGFGSRLLSDARRPEPQRSARDQLRPPPVTRHRPRTAPLALTKSFNELGEDPGVALHEAPLPGIARHGPGRAPPRSTSGSGRPGPSLLPPPATELGKPAAGSSTTRHPAYFPTASAAPSPGARQSAGGRSSHPGAGETLPGPRWTRSGFGRGRGRAVWAKSEKGRGLGPLRREHPGPSPVWGRGGARPGGGARAREPNPEAPAAAPEQSSRVRPPCVVVLRWRRVAAQHFSRWRGGFGGLAAGHRLPKDRKMEESVNQMQPLNEKQIANSEGGYVWQVTDMNRLHRFLCFGSEGGTYCIKEQKLGLENAEALIRLIEDGRGCEVIQEIKSFSQEGRTAKQEPTLFALAICSQCSDISTKQAAFKAVPEVCRIPTHLFTFIQFKKDLKESMKCGMWGRALRKAVADWYNEKGGMALALAVTKYKQRNGWSHKDLLRLSHLKPSSEGLAIVTKYITKGWKEVHEMYKEKALSVEAEKLLKYLEAVEKVKRTKDELEVIHLIEEHRLVREHLLTNHLKSKEVWKALLQEMPLTALLRNLGKMTANSVLEPGNSEVSLVCEKLCNEKLLKKARIHPFHVLIALETYKTGHGLRGKLKWRPDEEILQALDAAFYKTFKTVEPTGKRFLLAIDVSGSMDQRVLGSVLNASTVAAAMCMVVTRTEKDSSIVAFSDEMVPCPVTTDMTLQQVLLAMSQIPAGGTDCSLPMIWAQKTNTAADVFIVFTDNETFAGSVHPAIALREYRKNMDIPAKLIVCGMTSNGFTIADPDDRGMLDMCGFDTGALDVIRSFTLDMI", "length": 856 }, "evidence": [ { "id": "A0A8V0YF85", "url": "https://omabrowser.org/oma/group/A0A8V0YF85/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "O08848-1", "protein_name": "RNA-binding protein Ro60", "gene_name": "RO60", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEGSANQLQPLSETQVVNSEGGCVWQVTDMNRLRRFLCFGSEGGTYYIKEQKLGLENAEALIRLIEDGRGCEVIQEIKSFSQEGRTAKQEPLLFALAVCSQCADINTKQAAFKAVPEVCRIPTHLFTFIQFKKDLKESMKCGMWGRALRKAVADWYNEKGGMAVALVVTKYKQRNGWSHKDLLRLSHLKPSSEGLAIVTKYITKGWKEVHEEYKEKALSVEAEKLLKYLEAVEKVKRTKDDLEVIHLIEEHQLVREHLLTNHLKSKEVWKALLQEMPLTALLRNLGKMTANSVLEPGNSEVSLICEKLSNEKLLKKARIHPFHVLIALETYRAGHGLRGKLKWIPDKDILQALDAAFYTTFKTVEPTGKRFLLAVDVSASMNQRALGSVLNASTVAAAMCMVVTRTEKESSVVAFACDMVPFPVTTDMTLQQVLTAMNKVPAGNTDCSLPMIWAQKTDTAADVFVVFTDNETFAGQVHPAVALREYRKKMDIPAKLIVCGMTSNGFTIADPDDRGMLDMCGFDTAALDVIRNFTLDVI", "length": 538 }, "evidence": [ { "id": "A0A8V0YF85", "url": "https://omabrowser.org/oma/group/A0A8V0YF85/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P10155-1", "protein_name": "RNA-binding protein RO60", "gene_name": "RO60", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEESVNQMQPLNEKQIANSQDGYVWQVTDMNRLHRFLCFGSEGGTYYIKEQKLGLENAEALIRLIEDGRGCEVIQEIKSFSQEGRTTKQEPMLFALAICSQCSDISTKQAAFKAVSEVCRIPTHLFTFIQFKKDLKESMKCGMWGRALRKAIADWYNEKGGMALALAVTKYKQRNGWSHKDLLRLSHLKPSSEGLAIVTKYITKGWKEVHELYKEKALSVETEKLLKYLEAVEKVKRTRDELEVIHLIEEHRLVREHLLTNHLKSKEVWKALLQEMPLTALLRNLGKMTANSVLEPGNSEVSLVCEKLCNEKLLKKARIHPFHILIALETYKTGHGLRGKLKWRPDEEILKALDAAFYKTFKTVEPTGKRFLLAVDVSASMNQRVLGSILNASTVAAAMCMVVTRTEKDSYVVAFSDEMVPCPVTTDMTLQQVLMAMSQIPAGGTDCSLPMIWAQKTNTPADVFIVFTDNETFAGGVHPAIALREYRKKMDIPAKLIVCGMTSNGFTIADPDDRGMLDMCGFDTGALDVIRNFTLDMI", "length": 538 }, "evidence": [ { "id": "A0A8V0YF85", "url": "https://omabrowser.org/oma/group/A0A8V0YF85/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "cellular response to interferon-alpha", "id": "GO:0035457", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035457", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YF85", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF85" } ], "pmid": "" }, { "name": "regulation of gene expression", "id": "GO:0010468", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010468", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YF85", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF85" } ], "pmid": "" }, { "name": "cell projection organization", "id": "GO:0030030", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030030", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YF85", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF85" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YF85", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF85" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YF85", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF85" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YF85", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF85" } ], "pmid": "" }, { "name": "ribonucleoprotein complex", "id": "GO:1990904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990904", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YF85", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF85" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YF85", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF85" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 471, "end_pos": 473, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YF85", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF85" }, { "id": "PS50988", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50988" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "TROVE", "eco_id": "ECO_0000259", "start_pos": 17, "end_pos": 370, "start_aa": "Val", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 471, "end_pos": 473 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YF92-1", "uniprot_ac": "A0A8V0YF92", "uniprot_id": "A0A8V0YF92_CHICK", "mass": { "chemical_mass": 127164.0, "monoisotopic_mass": 127164.0 }, "refseq": {}, "gene_names": [ { "name": "SEL1L3", "type": "recommended", "evidence": [ { "id": "A0A8V0YF92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF92" } ] } ], "protein_names": [ { "name": "SEL1L family member 3", "type": "synonym", "evidence": [ { "id": "A0A8V0YF92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF92/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YF92", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF92" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SEL1L3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF92", "locus": { "chromosome": "4", "start_pos": 72935500, "end_pos": 72903701, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010010857", "url": "https://www.ensembl.org/id/ENSGALG00010010857" } ] } } ], "crossref": [ { "id": "A0A8V0YF92", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YF92", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR006597", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006597", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011990", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011990", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042756", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042756", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YF92", "url": "https://www.orthodb.org/?gene=A0A8V0YF92", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR44444", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR44444", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR44444:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR44444:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF08238", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08238", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YF92", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF92", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YF92-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF92-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": 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"tr|A0A8V0YFA9-1|A0A8V0YFA9_CHICK Isoform 1 of CD83 molecule OS=Gallus gallus OX=9031 GN=CD83 PE=4 SV=1 CANONICAL=A0A8V0YFA9-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YFA9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFA9/entry#A0A8V0YFA9-1", "sequence": { "sequence": "MGNILTGTLFSPRFPSAKPPQPSLLSSSQGLHYFKKEKAMTGQDFLSLYREPPAFKFHLHLSSKNWAEVLQTGKHSQKNKAQSLLHLSCWSTKTEALKIVWSLINGAAVAVPDVAVTCFEEALLSCKVLQDSSIAYQAVSWYKMAGVGDRIAWKVLDVESRHPKGLGGSLELSNTTFQLRIRNATSQDSGTYKCALGEQRGDHNLSGIITLKVTGCPRIEDEKLKKYKTELFMLTCLGIFYLLLIFFTCTCLRKESMSPSDKSRRDSKRTLTLINAHEMTTLRVLNSGSTCKSGLTSSSI", "length": 300, "header": "tr|A0A8V0YFA9-1|A0A8V0YFA9_CHICK Isoform 1 of CD83 molecule OS=Gallus gallus OX=9031 GN=CD83 PE=4 SV=1 CANONICAL=A0A8V0YFA9-1" }, "locus": { "chromosome": "2", "start_pos": 60433044, "end_pos": 60420376, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026023.1", "url": "https://www.ensembl.org/id/ENSGALT00010026023.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010014670.1", "url": "https://www.ensembl.org/id/ENSGALP00010014670.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 174, "end_pos": 176, "annotation": "n_glycosylation_sequon" }, { "start_pos": 183, "end_pos": 185, "annotation": "n_glycosylation_sequon" }, { "start_pos": 204, "end_pos": 206, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YFA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFA9" }, { "id": "PS50835", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50835" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ig-like", "eco_id": "ECO_0000259", "start_pos": 124, "end_pos": 210, "start_aa": "Leu", "end_aa": "Thr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 174, "end_pos": 176 }, { "start_pos": 183, "end_pos": 185 }, { "start_pos": 204, "end_pos": 206 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { 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"field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YFB1-1", "uniprot_ac": "A0A8V0YFB1", "uniprot_id": "A0A8V0YFB1_CHICK", "mass": { "chemical_mass": 50866.0, "monoisotopic_mass": 50866.0 }, "refseq": {}, "gene_names": [ { "name": "NPTXR", "type": "recommended", "evidence": [ { "id": "A0A8V0YFB1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFB1" } ] } ], "protein_names": [ { "name": "Neuronal pentraxin receptor", "type": "synonym", "evidence": [ { "id": "A0A8V0YFB1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFB1/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFB1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFB1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "NPTXR", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFB1", "locus": { "chromosome": "1", "start_pos": 50831220, "end_pos": 50825451, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012685", "url": "https://www.ensembl.org/id/ENSGALG00010012685" } ] } } ], "crossref": [ { "id": "A0A8V0YFB1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YFB1", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00152", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00152", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001759", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001759", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013320", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013320", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051360", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051360", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YFB1", "url": "https://www.orthodb.org/?gene=A0A8V0YFB1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR19277", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19277", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19277:SF94", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19277:SF94", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00354", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00354", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YFB1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFB1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YFB1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFB1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLAFLGAIICIIASVHPAGTAAPAAPTAADNDSAAAALLPAADKGLGALHGPAEALASAGPRLTGSTPLFSRFVCTPLSAECPAAAPGPAAAAGPEELLALRSAAAQLRRTALEQKERIRMDQETIRELTGKLSRCEGGLHSSPPAAGLRAAPRPGTMGHPPAEPPAVRELEEAVRALQERIDRIEQELPSRPNGSAPTAPALARDALHSKMEQLEEQLLAKILALQKERHAANTDRSQQQHDIEKELSALQNRVAELEHGAPGYNPPDAFKVTIPVQNNYMYARMKKSLPELYAFTICLWLKSKALSGLGTPFSYSVPTQANEIVLLEWGSNPLELLINDKVAQLPLSLKDKAWHHVCVAWTTRDGKWSAYQDGEQRGSGENLASWHAIKPQGVIILGQEQDTLGGRFDATQAFVGELAHFAVWDHMLAPAEILALANCTSRLQGNVIQWDDQAVEVFGGASKAAFTACDEGRKA", "length": 476, "header": "tr|A0A8V0YFB1-1|A0A8V0YFB1_CHICK Isoform 1 of Neuronal pentraxin receptor OS=Gallus gallus OX=9031 GN=NPTXR PE=4 SV=1 CANONICAL=A0A8V0YFB1-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YFB1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFB1/entry#A0A8V0YFB1-1", "sequence": { "sequence": "MLAFLGAIICIIASVHPAGTAAPAAPTAADNDSAAAALLPAADKGLGALHGPAEALASAGPRLTGSTPLFSRFVCTPLSAECPAAAPGPAAAAGPEELLALRSAAAQLRRTALEQKERIRMDQETIRELTGKLSRCEGGLHSSPPAAGLRAAPRPGTMGHPPAEPPAVRELEEAVRALQERIDRIEQELPSRPNGSAPTAPALARDALHSKMEQLEEQLLAKILALQKERHAANTDRSQQQHDIEKELSALQNRVAELEHGAPGYNPPDAFKVTIPVQNNYMYARMKKSLPELYAFTICLWLKSKALSGLGTPFSYSVPTQANEIVLLEWGSNPLELLINDKVAQLPLSLKDKAWHHVCVAWTTRDGKWSAYQDGEQRGSGENLASWHAIKPQGVIILGQEQDTLGGRFDATQAFVGELAHFAVWDHMLAPAEILALANCTSRLQGNVIQWDDQAVEVFGGASKAAFTACDEGRKA", "length": 476, "header": "tr|A0A8V0YFB1-1|A0A8V0YFB1_CHICK Isoform 1 of Neuronal pentraxin receptor OS=Gallus gallus OX=9031 GN=NPTXR PE=4 SV=1 CANONICAL=A0A8V0YFB1-1" }, "locus": { "chromosome": "1", "start_pos": 50830281, "end_pos": 50825650, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030334.1", "url": "https://www.ensembl.org/id/ENSGALT00010030334.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017597.1", "url": "https://www.ensembl.org/id/ENSGALP00010017597.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 199, "start_aa": "Thr", "end_pos": 199, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr199", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 27, "start_aa": "Thr", "end_pos": 27, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr27", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "glutamatergic synapse", "id": "GO:0098978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098978", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFB1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFB1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFB1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFB1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 194, "end_pos": 196, "annotation": "n_glycosylation_sequon" }, { "start_pos": 31, "end_pos": 33, "annotation": "n_glycosylation_sequon" }, { "start_pos": 439, "end_pos": 441, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YFB1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFB1" }, { "id": "PS51828", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51828" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Pentraxin (PTX)", "eco_id": "ECO_0000259", "start_pos": 269, "end_pos": 470, "start_aa": "Asp", "end_aa": "Cys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 27, 199 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 194, "end_pos": 196 }, { "start_pos": 31, "end_pos": 33 }, { "start_pos": 439, "end_pos": 441 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": 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This record is derived from a genomic sequence (NC_052575.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. 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"PTHR46806", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46806", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46806:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46806:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00431", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00431", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00754", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00754", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF03815", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03815", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_040522581", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040522581", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Y927", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y927", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y927-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y927-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YFB9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFB9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YFB9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFB9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGAAALPVLPLPLPTPGPGGRQRCTRRAERGPFASAATPAGRGMPLGGRPPGLAGGPGPGPPLRGREEEKGAGEKRGSCVSPGAGAMSPAGGARAAPSLLFSLLLAASAPLWLRAEKMGDGCGHVVMYQDSGTLASKNYPGTYPNYTLCEKKIQVPQGKRLILKIGDLDIESQKCESSYLTILSSSTLHGPYCGNMMPVPKEIILDSNEATIHFESGSHVSGRGFLLSYASSDHPDLITCLERANHYTKTEYSRYCPAGCRDIAGDISGNIEEGYRDTSLLCKSAIHAGVIADELGGQISVTQQKGISRYEGVVANGISSHDGSLSDKRFMFTSNGCNRSLSLEEGFLSKSQITASSYWEETNEFGQLFQWTPDKAWLQVLGLAWASNHSSSREWLEIDLGEKKRITGIKTTGSGSTLQNFNFYVKTFILNYRNNNSKWRTYRGILSNEEKVFQGNSDSGDIVRNNFIPPIVARYVRIIPQSWNQRIALKLELIGCRIMQVNSSFTHSMWQKTSQSTETSLGKEDRTVTEPIPSEETNLGLKLTAIIVPVLIVLCLFLFSGICICAALRKQEAKGLSYGLSNAQKSGCWKQIKQPFTRHQSTEFTISYNNEKETPQKLDLVTSDMADYQQPLMIGTGTVTRKGSTFRPMDTEEEGRRGSAEFENHYHCPHRANRHEYALPLTSQEPEYATPIIERHVTRENNFPSENGYNVPVISSQKHSLSAGSFSGSCKTDTRNGDYQTPQSVINYDKPKANGILTSVSYSTEYQKPQANALGSEGYSTPRDCLNPISQTAMTALL", "length": 798, "header": "tr|A0A8V0YFB9-1|A0A8V0YFB9_CHICK Isoform 1 of Discoidin, CUB and LCCL domain containing 1 OS=Gallus gallus OX=9031 GN=DCBLD1 PE=4 SV=1 CANONICAL=A0A8V0YFB9-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Y927-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFB9/entry#A0A8V0Y927-1", "sequence": { "sequence": "MPLGGRPPGLAGGPGPGPPLRGREEEKGAGEKRGSCVSPGAGAMSPAGGARAAPSLLFSLLLAASAPLWLRAEKMGDGCGHVVMYQDSGTLASKNYPGTYPNYTLCEKKIQVPQGKRLILKIGDLDIESQKCESSYLTILSSSTLHGPYCGNMMPVPKEIILDSNEATIHFESGSHVSGRGFLLSYASSDHPDLITCLERANHYTKTEYSRYCPAGCRDIAGDISGNIEEGYRDTSLLCKSAIHAGVIADELGGQISVTQQKGISRYEGVVANGISSHDGSLSDKRFMFTSNGCNRSLSLEEGFLSKSQITASSYWEETNEFGQLFQWTPDKAWLQVLGLAWASNHSSSREWLEIDLGEKKRITGIKTTGSGSTLQNFNFYVKTFILNYRNNNSKWRTYRGILSNEEKVFQGNSDSGDIVRNNFIPPIVARYVRIIPQSWNQRIALKLELIGCRIMQGLKLTAIIVPVLIVLCLFLFSGICICAALRKQEAKGLSYGLSNAQKSGCWKQIKQPFTRHQSTEFTISYNNEKETPQKLDLVTSDMADYQQPLMIGTGTVTRKGSTFRPMDTEEEGRRGSAEFENHYHCPHRANRHEYALPLTSQEPEYATPIIERHVTRENNFPSENGYNVPVISSQKHSLSAGSFSGSCKTDTRNGDYQTPQSVINYDKPKANGILTSVSYSTEYQKPQANALGSEGYSTPRDCLNPISQTAMTALL", "length": 716, "header": "tr|A0A8V0Y927-1|A0A8V0Y927_CHICK Computationally mapped isoform of Discoidin, CUB and LCCL domain containing 1 OS=Gallus gallus OX=9031 GN=DCBLD1 PE=4 SV=1 CANONICAL=A0A8V0YFB9-1" }, "locus": { "chromosome": "3", "start_pos": 63157811, "end_pos": 63111835, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029582.1", "url": "https://www.ensembl.org/id/ENSGALT00010029582.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017205.1", "url": "https://www.ensembl.org/id/ENSGALP00010017205.1" } ] } }, { "isoform_ac": "A0A8V0YFB9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFB9/entry#A0A8V0YFB9-1", "sequence": { "sequence": "MGAAALPVLPLPLPTPGPGGRQRCTRRAERGPFASAATPAGRGMPLGGRPPGLAGGPGPGPPLRGREEEKGAGEKRGSCVSPGAGAMSPAGGARAAPSLLFSLLLAASAPLWLRAEKMGDGCGHVVMYQDSGTLASKNYPGTYPNYTLCEKKIQVPQGKRLILKIGDLDIESQKCESSYLTILSSSTLHGPYCGNMMPVPKEIILDSNEATIHFESGSHVSGRGFLLSYASSDHPDLITCLERANHYTKTEYSRYCPAGCRDIAGDISGNIEEGYRDTSLLCKSAIHAGVIADELGGQISVTQQKGISRYEGVVANGISSHDGSLSDKRFMFTSNGCNRSLSLEEGFLSKSQITASSYWEETNEFGQLFQWTPDKAWLQVLGLAWASNHSSSREWLEIDLGEKKRITGIKTTGSGSTLQNFNFYVKTFILNYRNNNSKWRTYRGILSNEEKVFQGNSDSGDIVRNNFIPPIVARYVRIIPQSWNQRIALKLELIGCRIMQVNSSFTHSMWQKTSQSTETSLGKEDRTVTEPIPSEETNLGLKLTAIIVPVLIVLCLFLFSGICICAALRKQEAKGLSYGLSNAQKSGCWKQIKQPFTRHQSTEFTISYNNEKETPQKLDLVTSDMADYQQPLMIGTGTVTRKGSTFRPMDTEEEGRRGSAEFENHYHCPHRANRHEYALPLTSQEPEYATPIIERHVTRENNFPSENGYNVPVISSQKHSLSAGSFSGSCKTDTRNGDYQTPQSVINYDKPKANGILTSVSYSTEYQKPQANALGSEGYSTPRDCLNPISQTAMTALL", "length": 798, "header": "tr|A0A8V0YFB9-1|A0A8V0YFB9_CHICK Isoform 1 of Discoidin, CUB and LCCL domain containing 1 OS=Gallus gallus OX=9031 GN=DCBLD1 PE=4 SV=1 CANONICAL=A0A8V0YFB9-1" }, "locus": { "chromosome": "3", "start_pos": 63157940, "end_pos": 63111835, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029586.1", "url": "https://www.ensembl.org/id/ENSGALT00010029586.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017207.1", "url": "https://www.ensembl.org/id/ENSGALP00010017207.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 15, "start_aa": "Thr", "end_pos": 15, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr15", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 38, "start_aa": "Thr", "end_pos": 38, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr38", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0ABK0L6J8-1", "protein_name": "Discoidin, CUB and LCCL domain containing 1", "gene_name": "Dcbld1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGTGAGGPGVLALLFAVCAPLRLQAEELASEDGVIVVDRHITTICDGCGHIVTSQDSGTMTSKNYPGTYPNYTVCEKIITVPKGKRLILRLGDLNIESKTCASDYLLFSSATDQYGPYCGSWAVPKELWLNSNEVTVRFQSGSHISGRGFLLAYASSDHPDLITCLERGNHYSQEKYSKFCPAGCRDVAGDISGNTKDGYRDTSLLCKAAIHAGIITDELGGQINLLQSKGISHYEGILANGVLSRHGSLSEKRFLFTSPGMSITTVAIPSVIFIALLLTGTGIFAICRKKKKKGNPFVSAEAQKTGCWKQIKYPFARHQSAEFTISYDNEKEMTQKLDLITSDMADYQQPLMIGTGTVTRKGSTFRPMDTDTEEARVNTEASSHYDCPHRPGRHEYALPLTHSEPEYATPIVERHLLRAHTFSTQSGYRVPGPRLTHKHSLSSGGFPPAAGATQIESYQRPASPKPVGGGYDKPAAASSFLDSGDPASQSQMTSGGNDGYSAPRNGLAPLNQMAVTALL", "length": 520 }, "evidence": [ { "id": "A0A8V0YFB9", "url": "https://omabrowser.org/oma/group/A0A8V0YFB9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1QGI1-1", "protein_name": "Discoidin, CUB and LCCL domain-containing protein 1", "gene_name": "dcbld1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSGHTVLYGLILLYSIHPLVLAEKPDDGCGHYVLGQESGVLSSKNYPGTYPNNSWCEWRIRVPIGHTIILKFGDLDMKKRDCESDYLKVLKGSYGSENVYWEYCGDPMPKPSQLHTDSNELTIRFRSSQHITGRGFLLSYSTENHKELLTCLDRGSHFTTAKYRKYCPAGCAALAGEVSGDISLGYRHNSVLCKAAVHAGVIMDQFGGPITVENRRGLSYYPAVRANGIQSKDGSLSETLFTFVTNNCSQQTALQPALITTSLSTHNVSSDGSEVDWLPNSTRISEDLSNKHLLWLQIDLGEKRRITGILTTGLTIAGFEYFVKNFKIEYKERNRWRTFVQYNNSDEMVFEGNTNSLHQTRNTFHPSIISRYIRVVPQQWHRTIAMRLQLLGCSYVKPIPVNASSQVTQEAQPTQPIHNMTKPVASQADFVNLIVIIVPTILLVVLLLVAVCVVKMLHSKKTKENTYDSADTHHTGCWRQIKQPFTRHQSTEFTIKYSSEKDPIQKLDLVTSAMAAEYQQPLMLGTDTVSRKGSTFRPMDTETKDMESSHYDHLQTGIQYALPLTNQEPEYATPIIERHAFRKDPFIPDASYSVPGVVLNKSPSFRAVEGGNCRKVIGGLAGGYQTPQVKPDRGNSPEDIYDSPKIRKAVVLNGPEYQRPQIKSQDQECYSTPRDCVRLPFSGLRPDPEGSRSEPEGSSSDGS", "length": 703 }, "evidence": [ { "id": "A0A8V0YFB9", "url": "https://omabrowser.org/oma/group/A0A8V0YFB9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "G3N0M7-1", "protein_name": "Discoidin, CUB and LCCL domain containing 1", "gene_name": "DCBLD1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MTSKNYPWTYPNHTVCEKTITVPKGKRLILRLGDLDIESQTCASDYLLFTSSSDQYGPYCGSMTMPKELLLNTNEVTVRFESGSHTSGRGFLLTYASSDHPDLITCLDRANHYLKTEYSKFCPAGCRDVPGDISGNVVDGYRDTSLLCKAAIHAGVIADEVGGQISVFLRKGLSRYEGILANGVLSRDGSLSDKRFLFTSNGCSGSLSLEPDRQIRASSSWEWINETGDQVRWSPGQARLQDQGPSWASGDRSKNHKQREWLRIDLGEKKKITGIRTTGSTQSDFDFYVKSFVMNFRNNNSKWKTYKGIVNNEEKVFQGNSNFRDPVRNNFIPPIVARYVRVIPQTWHQRIALKVELLGCQVAPSRTQGNDSLVWHKTSVNTVGSTKGEDKTISKPIPSEEMPKGLNITTIVILLVLFFVLAAGVAIFAVLRKKKKKGNPYGSSKTQKTDCWKQIKYPFARHQSAEFTISYNNEKEMTQKLDLITSDIADYQQPLMIGTETVTRKGSTFRPMDTEADAAGPGTEAGGHYDCPLPAGRHEYALPLTNPEPEYATPIVERHLARAHTFSARSGYRVPGPRPAHKHSLSSGAFSPAAGYQRPPSPAPAEPGYDQPKGGGLAAGCAPPDHPKPQVSPASSAAYLAPRDCLRPLNPTAMTALL", "length": 658 }, "evidence": [ { "id": "A0A8V0YFB9", "url": "https://omabrowser.org/oma/group/A0A8V0YFB9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q8N8Z6-1", "protein_name": "Discoidin, CUB and LCCL domain-containing protein 1", "gene_name": "DCBLD1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVPGARGGGALARAAGRGLLALLLAVSAPLRLQAEELGDGCGHLVTYQDSGTMTSKNYPGTYPNHTVCEKTITVPKGKRLILRLGDLDIESQTCASDYLLFTSSSDQYGPYCGSMTVPKELLLNTSEVTVRFESGSHISGRGFLLTYASSDHPDLITCLERASHYLKTEYSKFCPAGCRDVAGDISGNMVDGYRDTSLLCKAAIHAGIIADELGGQISVLQRKGISRYEGILANGVLSRDGSLSDKRFLFTSNGCSRSLSFEPDGQIRASSSWQSVNESGDQVHWSPGQARLQDQGPSWASGDSSNNHKPREWLEIDLGEKKKITGIRTTGSTQSNFNFYVKSFVMNFKNNNSKWKTYKGIVNNEEKVFQGNSNFRDPVQNNFIPPIVARYVRVVPQTWHQRIALKVELIGCQITQGNDSLVWRKTSQSTSVSTKKEDETITRPIPSEETSTGINITTVAIPLVLLVVLVFAGMGIFAAFRKKKKKGSPYGSAEAQKTDCWKQIKYPFARHQSAEFTISYDNEKEMTQKLDLITSDMADYQQPLMIGTGTVTRKGSTFRPMDTDAEEAGVSTDAGGHYDCPQRAGRHEYALPLAPPEPEYATPIVERHVLRAHTFSAQSGYRVPGPQPGHKHSLSSGGFSPVAGVGAQDGDYQRPHSAQPADRGYDRPKAVSALATESGHPDSQKPPTHPGTSDSYSAPRDCLTPLNQTAMTALL", "length": 715 }, "evidence": [ { "id": "A0A8V0YFB9", "url": "https://omabrowser.org/oma/group/A0A8V0YFB9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9D4J3-1", "protein_name": "Discoidin, CUB and LCCL domain-containing protein 1", "gene_name": "Dcbld1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGTGAGGPSVLALLFAVCAPLRLQAEELGDGCGHIVTSQDSGTMTSKNYPGTYPNYTVCEKIITVPKGKRLILRLGDLNIESKTCASDYLLFSSATDQYGPYCGSWAVPKELRLNSNEVTVLFKSGSHISGRGFLLTYASSDHPDLITCLERGSHYFEEKYSKFCPAGCRDIAGDISGNTKDGYRDTSLLCKAAIHAGIITDELGGHINLLQSKGISHYEGLLANGVLSRHGSLSEKRFLFTTPGMNITTVAIPSVIFIALLLTGMGIFAICRKRKKKGNPYVSADAQKTGCWKQIKYPFARHQSTEFTISYDNEKEMTQKLDLITSDMADYQQPLMIGTGTVARKGSTFRPMDTDTEEVRVNTEASGHYDCPHRPGRHEYALPLTHSEPEYATPIVERHLLRAHTFSTQSGYRVPGPRPTHKHSHSSGGFPPATGATQVESYQRPASPKPVGGGYDKPAASSFLDSRDPASQSQMTSGGDDGYSAPRNGLAPLNQTAMTALL", "length": 503 }, "evidence": [ { "id": "A0A8V0YFB9", "url": "https://omabrowser.org/oma/group/A0A8V0YFB9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFB9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFB9" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFB9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFB9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "signaling receptor activity", "id": "GO:0038023", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038023", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFB9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFB9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 145, "end_pos": 147, "annotation": "n_glycosylation_sequon" }, { "start_pos": 338, "end_pos": 340, "annotation": "n_glycosylation_sequon" }, { "start_pos": 388, "end_pos": 390, "annotation": "n_glycosylation_sequon" }, { "start_pos": 435, "end_pos": 437, "annotation": "n_glycosylation_sequon" }, { "start_pos": 502, "end_pos": 504, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YFB9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFB9" }, { "id": "PS01180", "database": "PROSITE", "url": "https://prosite.expasy.org/PS01180" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CUB", "eco_id": "ECO_0000259", "start_pos": 122, "end_pos": 232, "start_aa": "Cys", "end_aa": "Ser", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0YFB9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFB9" }, { "id": "PS50022", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50022" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "F5/8 type C", "eco_id": "ECO_0000259", "start_pos": 337, "end_pos": 496, "start_aa": "Cys", "end_aa": "Cys", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0YFB9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFB9" }, { "id": "PS50820", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50820" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "LCCL", "eco_id": "ECO_0000259", "start_pos": 234, "end_pos": 330, "start_aa": "His", "end_aa": "Phe", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 15, 38 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 145, "end_pos": 147 }, { "start_pos": 338, "end_pos": 340 }, { "start_pos": 388, "end_pos": 390 }, { "start_pos": 435, "end_pos": 437 }, { "start_pos": 502, "end_pos": 504 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YIF5-1", "uniprot_ac": "A0A8V0YIF5", "uniprot_id": "A0A8V0YIF5_CHICK", "mass": { "chemical_mass": 97104.0, "monoisotopic_mass": 97104.0 }, "refseq": { "ac": "XP_015134036", "name": "zinc finger protein 185 isoform X4", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015134036" }, "gene_names": [ { "name": "ZNF185", "type": "recommended", "evidence": [ { "id": "A0A8V0YIF5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIF5" } ] }, { "name": "ZNF185", "type": "synonym", "evidence": [ { "id": "XP_015134036", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015134036" } ] } ], "protein_names": [ { "name": "Zinc finger protein 185 with LIM domain", "type": "synonym", "evidence": [ { "id": "A0A8V0YIF5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIF5/entry#names_and_taxonomy" } ] }, { "name": "zinc finger protein 185 isoform X4", "type": "synonym", "evidence": [ { "id": "XP_015134036", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015134036" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052535.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015134036.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015134036", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015134036" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIF5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIF5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ZNF185", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIF5", "locus": {} } ], "crossref": [ { "id": "A0A8V0YIF5", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YIF5", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd08368", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd08368", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "422301", "url": "https://www.ncbi.nlm.nih.gov/gene/422301", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001781", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001781", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052621", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052621", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR15468", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15468", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15468:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15468:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "XP_015134036", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015134036", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YA52", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YA52", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YA52-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YA52-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YFC3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFC3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YFC3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFC3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YGD9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGD9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YGD9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGD9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YGE8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGE8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YGE8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGE8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YIF5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIF5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YIF5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIF5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YII1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YII1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YII1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YII1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YN83", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN83", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YN83-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN83-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YN92", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN92", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YN92-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN92-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YNA4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNA4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YNA4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNA4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YNC0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNC0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YNC0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNC0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MMSLGVSKDRVITPTDEDRRRIIKQMKVRTTLKSDKSWIHHQNSDSEDEKKSSPLSGRTGGGSTGSAPTALQSDRSPAPKPQSGYLIRGVFTKTIDKTPSVPNSPSSKAAQKNSTAVKGPSSCHSSGYRMTTEDYKKLAPYNVKQKSVDLDEEDVPFSPDEHKKRTEAANSVLRRTASRERAYVLSAAKKSSGSPTQEFPPLFAKRIEIEEEGQQRRNPTVSDSCKFTVDDNSTNGLKKPTVGPSWNAPKTTAVSPTSTEIGSKSPTTTTLRETSEKISTCAEIRNGESRQTPNGNSALETVPQHGDGDKLLKEKSEPFSWDKPTATAVSTNGRSDSGYSDRSADAVDKLHQQYESSPYTDDAKSEPARSEPDAGTHSAAASSRSVLQSNVPSPPSEGTPAHLEDTEYSFKRSVLNYEERSSTQESRFMSPTVPAYTKPDWNEAKSFQDFKEGNTLRNREHESTLASRDHKPEVVQGGFSDSSHHAEKGQEPPDVHPEPPRSNKYADHDLSMAMSMSYSKDSTSDGVHTNTGVSSYVQSEEFASRRSSSLPREGSTTAPESQSGNESNTCWERTTPAYEEQPPPTMDSHHESPGAWRHNEPSPMAASRSNFSSKESALGAYETQHPMPLYMDRQPFNTSVSAPSHRIPSYVDSQGFSTRRPILDYEGRVYDGRSSPRSSRYDSGSARGHCEFNLITTSHHSLPRDTTMSISPRSHRVPFYMDSLNCNSTRLLSSSSERICTPIATLPYNSPAASGYQPDSSTAGKGVLFVKEYVNSSELSASPRYGSGSLVDLTDLERGTYSHHSYVSSAPLQRSSEPVCTYCSREIRDCPKIIIEHLNIYCHEYCFRCGICHKAMGDLLDKIFIHRDIVHCDKCYEKLF", "length": 880, "header": "tr|A0A8V0YIF5-1|A0A8V0YIF5_CHICK Isoform 1 of Zinc finger protein 185 with LIM domain OS=Gallus gallus OX=9031 GN=ZNF185 PE=1 SV=1 CANONICAL=A0A8V0YIF5-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YA52-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIF5/entry#A0A8V0YA52-1", "sequence": { "sequence": "MMSLGVSKDRVITPTDEDRRRIIKQMKVRTTLKSDKSWIHHQNSDSEDEKKSSPLSGRTGGGSTGSAPTALQSDRSPAPKPQSGYLIRGVFTKTIDKTPSVPNSPSSKAAQKNSTAVKGPSSCHSSGYRMTTEDYKKLAPYNVKQKSVDLDEEDVPFSPDEHKKRTEAANSVLRRTASRERAYVLSAAKKSSGSPTQEFPPLFAKRIEIEEEGQQRRNPTVSDSCKFTVDDNSTNGLKKPTVGPSWNAPKTTAVSPTSTEIGSKSPTTTTLRETSEKISTCAEIRNGESRQTPNGNSALETVPQHGDGDKLLKEKSEPFSWDKPTATAVSTNGSYSEHTEANNGFYLPKSDSGYSDRSADAVDKLHQQYESSPYTDDAKSEPARSEPDAGTHSAAASSRSVLQSNVPSPPSEGTPAHLEDTEYSFKRSVLNYEERSSTQESRFMSPTVPAYTKPDWNEAKSFQDFKEGNTLRNREHESTLASRDHKPEVVQGGFSDSSHHAEKGQEPPDVHPEPPRSNKYADHDLSMAMSMSYSKDSTSDGVHTNTGVSSYVQSEEFASRRSSSLPREGSTTAPESQSGNESNTCWERTTPAYEEQPPPTMDSHHESPGAWRHNEPSPMAARSNFSSKESALGAYETQHPMPLYMDRQPFNTSVSAPSHRIPSYVDSQGFSTRRLLSSSSERICTPIATLPYNSPAASGYQPDSSTAGKGVLFVKEYVNSSELSASPRYGSGSLVDLTDLERGTYSHHSYVSSAPLQRSSEPVCTYCSREIRDCPKIIIEHLNIYCHEYCFRCGICHKAMGDLLDKIFIHRDIVHCDKCYEKLF", "length": 824, "header": "tr|A0A8V0YA52-1|A0A8V0YA52_CHICK Computationally mapped isoform of Zinc finger protein 185 with LIM domain OS=Gallus gallus OX=9031 GN=ZNF185 PE=1 SV=1 CANONICAL=A0A8V0YIF5-1" }, "locus": { "chromosome": "4", "start_pos": 11207920, "end_pos": 11177646, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030349.1", "url": "https://www.ensembl.org/id/ENSGALT00010030349.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017603.1", "url": "https://www.ensembl.org/id/ENSGALP00010017603.1" } ] } }, { "isoform_ac": "A0A8V0YFC3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIF5/entry#A0A8V0YFC3-1", "sequence": { "sequence": "MMSLGVSKDRVITPTDEDRRRIIKQMKVRTTLKSDKSWIHHQNSDSEDEKKSSPLSGRTGGGSTGSAPTALQSDRSPAPKPQSGYLIRGVFTKTIDKTPSVPNSPSSKAAQKNSTAVKGPSSCHSSGYRMTTEDYKKLAPYNVKQKSVDLDEEDVPFSPDEHKKRTEAANSVLRRTASRERAYVLSAAKKSSGSPTQEFPPLFAKRIEIEEEGQQRRNPTVSDSCKFTVDDNSTNGLKKPTVGPSWNAPKTTAVSPTSTEIGSKSPTTTTLRETSEKISTCAEIRNGESRQTPNGNSALETVPQHGDGDKLLKEKSEPFSWDKPTATAVSTNGSYSEHTEANNGFYLPKSDSGYSDRSADAVDKLHQQYESSPYTDDAKSEPARSEPDAGTHSAAASSRSVLQSNVPSPPSEGTPAHLEDTEYSFKRSVLNYEERSSTQESRFMSPTVPAYTKPDWNEAKSFQDFKEGNTLRNREHESTLASRDHKPEVVQGGFSDSSHHAEKGQEPPDVHPEPPRSNKYADHDLSMAMSMSYSKDSTSDGVHTNTGVSSYVQSEEFASRRSSSLPREGSTTAPESQSGNESNTCWERTTPAYEEQPPPTMDSHHESPGAWRHNEPSPMAASRSNFSSKESALGAYETQHPMPLYMDRQPFNTSVSAPSHRIPSYVDSQGFSTRRPILDYEGRVYDGRSSPRSSRYDSGSARGHCEFNLITTRLLSSSSERICTPIATLPYNSPAASGYQPDSSTAGKGVLFVKEYVNSSELSASPRYGSGSLVDLTDLERGTYSHHSYVSSAPLQRSSEPVCTYCSREIRDCPKIIIEHLNIYCHEYCFRCGICHKAMGDLLDKIFIHRDIVHCDKCYEKLF", "length": 863, "header": "tr|A0A8V0YFC3-1|A0A8V0YIF5_CHICK Computationally mapped isoform of Zinc finger protein 185 with LIM domain OS=Gallus gallus OX=9031 GN=ZNF185 PE=1 SV=1 CANONICAL=A0A8V0YIF5-1" }, "locus": { "chromosome": "4", "start_pos": 11207920, "end_pos": 11177646, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030353.1", "url": "https://www.ensembl.org/id/ENSGALT00010030353.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017607.1", "url": "https://www.ensembl.org/id/ENSGALP00010017607.1" } ] } }, { "isoform_ac": "A0A8V0YGD9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIF5/entry#A0A8V0YGD9-1", "sequence": { "sequence": "MKVRTTLKSDKSWIHHQNSDSEDEKKSSPLSGRTGGGSTGSAPTALQSDRSPAPKPQSGYLIRGVFTKTIDKTPSVPNSPSSKAAQKNSTAVKGPSSCHSSGYRMTTEDYKKLAPYNVKQKSVDLDEEDVPFSPDEHKKRTEAANSVLRRTASRERAYVLSAAKKSSGSPTQEFPPLFAKRIEIEEEGQQRRNPTVSDSCKFTVDDNSTNGLKKPTVGPSWNAPKTTAVSPTSTEIGSKSPTTTTLRETSEKISTCAEIRNGESRQTPNGNSALETVPQHGDGDKLLKEKSEPFSWDKPTATAVSTNGSYSEHTEANNGFYLPKSDSGYSDRSADAVDKLHQQYESSPYTDDAKSEPARSEPDAGTHSAAASSRSVLQSNVPSPPSEGTPAHLEDTEYSFKRSVLNYEERSSTQESRFMSPTVPAYTKPDWNEAKSFQDFKEGNTLRNREHESTLASRDHKPEVVQGGFSDSSHHAEKGQEPPDVHPEPPRSNKYADHDLSMAMSMSYSKDSTSDGVHTNTGVSSYVQSEEFASRRSSSLPREGSTTAPESQSGNESNTCWERTTPAYEEQPPPTMDSHHESPGAWRHNEPSPMAARSNFSSKESALGAYETQHPMPLYMDRQPFNTSVSAPSHRIPSYVDSQGFSTRRPILDYEGRVYDGRSSPRSSRYDSGSARGHCEFNLITTSHHSLPRDTTMSISPRSHRVPFYMDSLNCNSTRLLSSSSERICTPIATLPYNSPAASGYQPDSSTAGKGVLFVKEYVNSSELSASPRYGSGSLVDLTDLERGTYSHHSYVSSAPLQRSSEPVCTYCSREIRDCPKIIIEHLNIYCHEYCFRCGICHKAMGDLLDKIFIHRDIVHCDKCYEKLF", "length": 869, "header": "tr|A0A8V0YGD9-1|A0A8V0YGD9_CHICK Computationally mapped isoform of Zinc finger protein 185 with LIM domain OS=Gallus gallus OX=9031 GN=ZNF185 PE=1 SV=1 CANONICAL=A0A8V0YIF5-1" }, "locus": { "chromosome": "4", "start_pos": 11206247, "end_pos": 11177646, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030316.1", "url": "https://www.ensembl.org/id/ENSGALT00010030316.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017585.1", "url": "https://www.ensembl.org/id/ENSGALP00010017585.1" } ] } }, { "isoform_ac": "A0A8V0YGE8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIF5/entry#A0A8V0YGE8-1", "sequence": { "sequence": "MMSLGVSKDRVITPTDEDRRRIIKQMKVRTTLKSDKSWIHHQNSDSEDEKKSSPLSGRTGGGSTGSAPTALQSDRSPAPKPQSGYLIRGVFTKTIDKTPSVPNSPSSKAAQKNSTAVKGPSSCHSSGYRMTTEDYKKLAPYNVKQKSVDLDEEDVPFSPDEHKKRTEAANSVLRRTASRERAYVLSAAKKSSGSPTQEFPPLFAKRIEIEEEGQQRRNPTVSDSCKFTVDDNSTNGLKKPTVGPSWNAPKTTAVSPTSTEIGSKSPTTTTLRETSEKISTCAEIRNGESRQTPNGNSALETVPQHGDGDKLLKEKSEPFSWDKPTATAVSTNGSYSEHTEANNGFYLPKSDSGYSDRSADAVDKLHQQYESSPYTDDAKSEPARSEPDAGTHSAAASSRSVLQSNVPSPPSEGTPAHLEDTEYSFKRSVLNYEERSSTQESRFMSPTVPAYTKPDWNEAKSFQDFKEGNTLRNREHESTLASRDHKPEVVQGGSMSYSKDSTSDGVHTNTGVSSYVQSEEFASRRSSSLPREGSTTAPESQSGNESNTCWERTTPAYEEQPPPTMDSHHESPGAWRHNEPSPMAASRSNFSSKESALGAYETQHPMPLYMDRQPFNTSVSAPSHRIPSYVDSQGFSTRRLLSSSSERICTPIATLPYNSPAASGYQPDSSTAGKGVLFVKEYVNSSELSASPRYGSGSLVDLTDLERGTYSHHSYVSSAPLQRSSEPVCTYCSREIRDCPKIIIEHLNIYCHEYCFRCGICHKAMGDLLDKIFIHRDIVHCDKCYEKLF", "length": 789, "header": "tr|A0A8V0YGE8-1|A0A8V0YGE8_CHICK Computationally mapped isoform of Zinc finger protein 185 with LIM domain OS=Gallus gallus OX=9031 GN=ZNF185 PE=1 SV=1 CANONICAL=A0A8V0YIF5-1" }, "locus": { "chromosome": "4", "start_pos": 11207920, "end_pos": 11177646, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030331.1", "url": "https://www.ensembl.org/id/ENSGALT00010030331.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017595.1", "url": "https://www.ensembl.org/id/ENSGALP00010017595.1" } ] } }, { "isoform_ac": "A0A8V0YIF5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIF5/entry#A0A8V0YIF5-1", "sequence": { "sequence": "MMSLGVSKDRVITPTDEDRRRIIKQMKVRTTLKSDKSWIHHQNSDSEDEKKSSPLSGRTGGGSTGSAPTALQSDRSPAPKPQSGYLIRGVFTKTIDKTPSVPNSPSSKAAQKNSTAVKGPSSCHSSGYRMTTEDYKKLAPYNVKQKSVDLDEEDVPFSPDEHKKRTEAANSVLRRTASRERAYVLSAAKKSSGSPTQEFPPLFAKRIEIEEEGQQRRNPTVSDSCKFTVDDNSTNGLKKPTVGPSWNAPKTTAVSPTSTEIGSKSPTTTTLRETSEKISTCAEIRNGESRQTPNGNSALETVPQHGDGDKLLKEKSEPFSWDKPTATAVSTNGRSDSGYSDRSADAVDKLHQQYESSPYTDDAKSEPARSEPDAGTHSAAASSRSVLQSNVPSPPSEGTPAHLEDTEYSFKRSVLNYEERSSTQESRFMSPTVPAYTKPDWNEAKSFQDFKEGNTLRNREHESTLASRDHKPEVVQGGFSDSSHHAEKGQEPPDVHPEPPRSNKYADHDLSMAMSMSYSKDSTSDGVHTNTGVSSYVQSEEFASRRSSSLPREGSTTAPESQSGNESNTCWERTTPAYEEQPPPTMDSHHESPGAWRHNEPSPMAASRSNFSSKESALGAYETQHPMPLYMDRQPFNTSVSAPSHRIPSYVDSQGFSTRRPILDYEGRVYDGRSSPRSSRYDSGSARGHCEFNLITTSHHSLPRDTTMSISPRSHRVPFYMDSLNCNSTRLLSSSSERICTPIATLPYNSPAASGYQPDSSTAGKGVLFVKEYVNSSELSASPRYGSGSLVDLTDLERGTYSHHSYVSSAPLQRSSEPVCTYCSREIRDCPKIIIEHLNIYCHEYCFRCGICHKAMGDLLDKIFIHRDIVHCDKCYEKLF", "length": 880, "header": "tr|A0A8V0YIF5-1|A0A8V0YIF5_CHICK Isoform 1 of Zinc finger protein 185 with LIM domain OS=Gallus gallus OX=9031 GN=ZNF185 PE=1 SV=1 CANONICAL=A0A8V0YIF5-1" }, "locus": { "chromosome": "4", "start_pos": 11207920, "end_pos": 11177646, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030322.1", "url": "https://www.ensembl.org/id/ENSGALT00010030322.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017586.1", "url": "https://www.ensembl.org/id/ENSGALP00010017586.1" } ] } }, { "isoform_ac": "A0A8V0YII1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIF5/entry#A0A8V0YII1-1", "sequence": { "sequence": "MMSLGVSKDRVITPTDEDRRRIIKQMKVRTTLKSDKSWIHHQNSDSEDEKKSSPLSGRTGGGSTGSAPTALQSDRSPAPKPQSGYLIRGVFTKTIDKTPSVPNSPSSKAAQKNSTAVKGPSSCHSSGYRMTTEDYKKLAPYNVKQKSVDLDEEDVPFSPDEHKKRTEAANSVLRRTASRERAYVLSAAKKSSGSPTQEFPPLFAKRIEIEEEGQQRRNPTVSDSCKFTVDDNSTNGLKKPTVGPSWNAPKTTAVSPTSTEIGSKSPTTTTLRETSEKISTCAEIRNGESRQTPNGNSALETVPQHGDGDKLLKEKSEPFSWDKPTATAVSTNGSYSEHTEANNGFYLPKSDSGYSDRSADAVDKLHQQYESSPYTDDAKSEPARSEPDAGTHSAAASSRSVLQSNVPSPPSEGTPAHLEDTEYSFKRSVLNYEERSSTQESRFMSPTVPAYTKPDWNEAKSFQDFKEGNTLRNREHESTLASRDHKPEVVQGGFSDSSHHAEKGQEPPDVHPEPPRSNKYADHDLSMAMSMSYSKDSTSDGVHTNTGVSSYVQSEEFASRRSSSLPREGSTTAPESQSGNESNTCWERTTPAYEEQPPPTMDSHHESPGAWRHNEPSPMAASRSNFSSKESALGAYETQHPMPLYMDRQPFNTSVSAPSHRIPSYVDSQGFSTRRPILDYEGRVYDGRSSPRSSRYDSGSARGHCEFNLITTSHHSLPRDTTMSISPRSHRVPFYMDSLNCNSTRKGVLFVKEYVNSSELSASPRYGSGSLVDLTDLERGTYSHHSYVSSAPLQRSSEPVCTYCSREIRDCPKIIIEHLNIYCHEYCFRCGICHKAMGDLLDKIFIHRDIVHCDKCYEKLF", "length": 861, "header": "tr|A0A8V0YII1-1|A0A8V0YII1_CHICK Computationally mapped isoform of Zinc finger protein 185 with LIM domain OS=Gallus gallus OX=9031 GN=ZNF185 PE=1 SV=1 CANONICAL=A0A8V0YIF5-1" }, "locus": { "chromosome": "4", "start_pos": 11207920, "end_pos": 11177646, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030359.1", "url": "https://www.ensembl.org/id/ENSGALT00010030359.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017611.1", "url": "https://www.ensembl.org/id/ENSGALP00010017611.1" } ] } }, { "isoform_ac": "A0A8V0YN83-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIF5/entry#A0A8V0YN83-1", "sequence": { "sequence": "MKVRTTLKSDKSWIHHQNSDSEDEKKSSPLSGRTGGGSTGSAPTALQSDRSPAPKPQSGYLIRGVFTKTIDKTPSVPNSPSSKAAQKNSTAVKGPSSCHSSGYRMTTEDYKKLAPYNVKQKSVDLDEEDVPFSPDEHKKRTEAANSVLRRTASRERAYVLSAAKKSSGSPTQEFPPLFAKRIEIEEEGQQRRNPTVSDSCKFTVDDNSTNGLKKPTVGPSWNAPKTTAVSPTSTEIGSKSPTTTTLRETSEKISTCAEIRNGESRQTPNGNSALETVPQHGDGDKLLKEKSEPFSWDKPTATAVSTNGSYSEHTEANNGFYLPKSDSGYSDRSADAVDKLHQQYESSPYTDDAKSEPARSEPDAGTHSAAASSRSVLQSNVPSPPSEGTPAHLEDTEYSFKRSVLNYEERSSTQESRFMSPTVPAYTKPDWNEAKSFQDFKEGNTLRNREHESTLASRDHKPEVVQGGFSDSSHHAEKGQEPPDVHPEPPRSNKYADHDLSMAMSMSYSKDSTSDGVHTNTGVSSYVQSEEFASRRSSSLPREGSTTAPESQSGNESNTCWERTTPAYEEQPPPTMDSHHESPGAWRHNEPSPMAASRSNFSSKESALGAYETQHPMPLYMDRQPFNTSVSAPSHRIPSYVDSQGFSTRRPILDYEGRVYDGRSSPRSSRYDSGSARGHCEFNLITTSHHSLPRDTTMSISPRSHRVPFYMDSLNCNSTRLLSSSSERICTPIATLPYNSPAASGYQPDSSTAGKGVLFVKEYVNSSELSASPRYGSGSLVDLTDLERGTYSHHSYVSSAPLQRSSEPVCTYCSREIRDCPKIIIEHLNIYCHEYCFRCGICHKAMGDLLDKIFIHRDIVHCDKCYEKLF", "length": 870, "header": "tr|A0A8V0YN83-1|A0A8V0YN83_CHICK Computationally mapped isoform of Zinc finger protein 185 with LIM domain OS=Gallus gallus OX=9031 GN=ZNF185 PE=1 SV=1 CANONICAL=A0A8V0YIF5-1" }, "locus": { "chromosome": "4", "start_pos": 11206247, "end_pos": 11177646, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030305.1", "url": "https://www.ensembl.org/id/ENSGALT00010030305.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017579.1", "url": "https://www.ensembl.org/id/ENSGALP00010017579.1" } ] } }, { "isoform_ac": "A0A8V0YN92-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIF5/entry#A0A8V0YN92-1", "sequence": { "sequence": "MMSLGVSKDRVITPTDEDRRRIIKQMKVRTTLKSDKSWIHHQNSDSEDEKKSSPLSGRTGGGSTGSAPTALQSDRSPAPKPQSGYLIRGVFTKTIDKTPSVPNSPSSKAAQKNSTAVKGPSSCHSSGYRMTTEDYKKLAPYNVKQKSVDLDEEDVPFSPDEHKKRTEAANSVLRRTASRERAYVLSAAKKSSGSPTQEFPPLFAKRIEIEEEGQQRRNPTVSDSCKFTVDDNSTEIGSKSPTTTTLRETSEKISTCAEIRNGESRQTPNGNSALETVPQHGDGDKLLKEKSEPFSWDKPTATAVSTNGSYSEHTEANNGFYLPKSDSGYSDRSADAVDKLHQQYESSPYTDDAKSEPARSEPDAGTHSAAASSRSVLQSNVPSPPSEGTPAHLEDTEYSFKRSVLNYEERSSTQESRFMSPTVPAYTKPDWNEAKSFQDFKEGNTLRNREHESTLASRDHKPEVVQGGFSDSSHHAEKGQEPPDVHPEPPRSNKYADHDLSMAMSMSYSKDSTSDGVHTNTGVSSYVQSEEFASRRSSSLPREGSTTAPESQSGNESNTCWERTTPAYEEQPPPTMDSHHESPGAWRHNEPSPMAASRSNFSSKESALGAYETQHPMPLYMDRQPFNTSVSAPSHRIPSYVDSQGFSTRRPILDYEGRVYDGRSSPRSSRYDSGSARGHCEFNLITTSHHSLPRDTTMSISPRSHRVPFYMDSLNCNSTRLLSSSSERICTPIATLPYNSPAASGYQPDSSTAGKGVLFVKEYVNSSELSASPRYGSGSLVDLTDLERGTYSHHSYVSSAPLQRSSEPVCTYCSREIRDCPKIIIEHLNIYCHEYCFRCGICHKAMGDLLDKIFIHRDIVHCDKCYEKLF", "length": 870, "header": "tr|A0A8V0YN92-1|A0A8V0YN92_CHICK Computationally mapped isoform of Zinc finger protein 185 with LIM domain OS=Gallus gallus OX=9031 GN=ZNF185 PE=1 SV=1 CANONICAL=A0A8V0YIF5-1" }, "locus": { "chromosome": "4", "start_pos": 11207920, "end_pos": 11177646, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030326.1", "url": "https://www.ensembl.org/id/ENSGALT00010030326.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017589.1", "url": "https://www.ensembl.org/id/ENSGALP00010017589.1" } ] } }, { "isoform_ac": "A0A8V0YNA4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIF5/entry#A0A8V0YNA4-1", "sequence": { "sequence": "MMSLGVSKDRVITPTDEDRRRIIKQMKVRTTLKSDKSWIHHQNSDSEDEKKSSPLSGRTGGGSTGSAPTALQSDRSPAPKPQSGYLIRGVFTKTIDKTPSVPNSPSSKAAQKNSTAVKGPSSCHSSGYRMTTEDYKKLAPYNVKQKSVDLDEEDVPFSPDEHKKRTEAANSVLRRTASRERAYVLSAAKKSSGSPTQEFPPLFAKRIEIEEEGQQRRNPTVSDSCKFTVDDNSTNGLKKPTVGPSWNAPKTTAVSPTSTEIGSKSPTTTTLRETSEKISTCAEIRNGESRQTPNGNSALETVPQHGDGDKLLKEKSEPFSWDKPTATAVSTNGSYSEHTEANNGFYLPKSDSGYSDRSADAVDKLHQQYESSPYTDDAKSEPARSEPDAGTHSAAASSRSVLQSNVPSPPSEGTPAHLEDTEYSFKRSVLNYEERSSTQESRFMSPTVPAYTKPDWNEAKSFQDFKEGNTLRNREHESTLASRDHKPEVVQGGFSDSSHHAEKGQEPPDVHPEPPRSNKYADHDLSMAMSMSYSKDSTSDGVHTNTGVSSYVQSEEFASRRSSSLPREGSTTAPESQSGNESNTCWERTTPAYEEQPPPTMDSHHESPGAWRHNEPSPMAARSNFSSKESALGAYETQHPMPLYMDRQPFNTSVSAPSHRIPSYVDSQGFSTRRKGVLFVKEYVNSSELSASPRYGSGSLVDLTDLERGTYSHHSYVSSAPLQRSSEPVCTYCSREIRDCPKIIIEHLNIYCHEYCFRCGICHKAMGDLLDKIFIHRDIVHCDKCYEKLF", "length": 790, "header": "tr|A0A8V0YNA4-1|A0A8V0YNA4_CHICK Computationally mapped isoform of Zinc finger protein 185 with LIM domain OS=Gallus gallus OX=9031 GN=ZNF185 PE=1 SV=1 CANONICAL=A0A8V0YIF5-1" }, "locus": { "chromosome": "4", "start_pos": 11207920, "end_pos": 11177646, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030340.1", "url": "https://www.ensembl.org/id/ENSGALT00010030340.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017599.1", "url": "https://www.ensembl.org/id/ENSGALP00010017599.1" } ] } }, { "isoform_ac": "A0A8V0YNC0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIF5/entry#A0A8V0YNC0-1", "sequence": { "sequence": "MMSLGVSKDRVITPTDEDRRRIIKQMKVRTTLKSDKSWIHHQNSDSEDEKKSSPLSGRTGGGSTGSAPTALQSDRSPAPKPQSGYLIRGVFTKTIDKTPSVPNSPSSKAAQKNSTAVKGPSSCHSSGYRMTTEDYKKLAPYNVKQKSVDLDEEDVPFSPDEHKKRTEAANSVLRRTASRERAYVLSAAKKSSGSPTQEFPPLFAKRIEIEEEGQQRRNPTVSDSCKFTVDDNSTNGLKKPTVGPSWNAPKTTAVSPTSTEIGSKSPTTTTLRETSEKISTCAEIRNGESRQTPNGNSALETVPQHGDGDKLLKEKSEPFSWDKPTATAVSTNGSYSEHTEANNGFYLPKSDSGYSDRSADAVDKLHQQYESSPYTDDAKSEPARSEPDAGTHSAAASSRSVLQSNVPSPPSEGTPAHLEDTEYSFKRSVLNYEERSSTQESRFMSPTVPAYTKPDWNEAKSFQDFKEGNTLRNREHESTLASRDHKPEVVQGGFSDSSHHAEKGQEPPDVHPEPPRSNKYADHDLSMAMSMSYSKDSTSDGVHTNTGVSSYVQSEEFASRRSSSLPREGSTTAPESQSGNESNTCWERTTPAYEEQPPPTMDSHHESPGAWRHNEPSPMAASRSNFSSKESALGAYETQHPMPLYMDRQPFNTSVSAPSHRIPSYVDSQGFSTRSHHSLPRDTTMSISPRSHRVPFYMDSLNCNSTRLLSSSSERICTPIATLPYNSPAASGYQPDSSTAGKGVLFVKEYVNSSELSASPRYGSGSLVDLTDLERGTYSHHSYVSSAPLQRSSEPVCTYCSREIRDCPKIIIEHLNIYCHEYCFRCGICHKAMGDLLDKIFIHRDIVHCDKCYEKLF", "length": 857, "header": "tr|A0A8V0YNC0-1|A0A8V0YNC0_CHICK Computationally mapped isoform of Zinc finger protein 185 with LIM domain OS=Gallus gallus OX=9031 GN=ZNF185 PE=1 SV=1 CANONICAL=A0A8V0YIF5-1" }, "locus": { "chromosome": "4", "start_pos": 11207920, "end_pos": 11177646, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030366.1", "url": "https://www.ensembl.org/id/ENSGALT00010030366.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017614.1", "url": "https://www.ensembl.org/id/ENSGALP00010017614.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 257, "start_aa": "Thr", "end_pos": 257, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr257", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 399, "start_aa": "Thr", "end_pos": 399, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr399", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIF5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIF5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 113, "end_pos": 115, "annotation": "n_glycosylation_sequon" }, { "start_pos": 232, "end_pos": 234, "annotation": "n_glycosylation_sequon" }, { "start_pos": 565, "end_pos": 567, "annotation": "n_glycosylation_sequon" }, { "start_pos": 610, "end_pos": 612, "annotation": "n_glycosylation_sequon" }, { "start_pos": 637, "end_pos": 639, "annotation": "n_glycosylation_sequon" }, { "start_pos": 727, "end_pos": 729, "annotation": "n_glycosylation_sequon" }, { "start_pos": 775, "end_pos": 777, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YIF5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIF5" }, { "id": "PS50023", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50023" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "LIM zinc-binding", "eco_id": "ECO_0000259", "start_pos": 818, "end_pos": 880, "start_aa": "Pro", "end_aa": "Phe", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 257, 399 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 113, "end_pos": 115 }, { "start_pos": 232, "end_pos": 234 }, { "start_pos": 565, "end_pos": 567 }, { "start_pos": 610, "end_pos": 612 }, { "start_pos": 637, "end_pos": 639 }, { "start_pos": 727, "end_pos": 729 }, { "start_pos": 775, "end_pos": 777 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": 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"field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YGH2-1", "uniprot_ac": "A0A8V0YGH2", "uniprot_id": "A0A8V0YGH2_CHICK", "mass": { "chemical_mass": 43097.0, "monoisotopic_mass": 43097.0 }, "refseq": { "ac": "XP_040526712", "name": "LOW QUALITY PROTEIN: E3 ubiquitin-protein ligase RNF128 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040526712" }, "gene_names": [ { "name": "RNF128", "type": "recommended", "evidence": [ { "id": "A0A8V0YGH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGH2" } ] }, { "name": "RNF128", "type": "synonym", "evidence": [ { "id": "XP_040526712", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040526712" } ] } ], "protein_names": [ { "name": "LOW QUALITY PROTEIN: E3 ubiquitin-protein ligase RNF128 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_040526712", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040526712" } ] }, { "name": "Ring finger protein 128", "type": "synonym", "evidence": [ { "id": "A0A8V0YGH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGH2/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## frameshifts :: corrected 1 indel ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052576.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040526712", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040526712" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGH2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGH2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RNF128", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGH2", "locus": { "chromosome": "4", "start_pos": 17402119, "end_pos": 17281529, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012699", "url": "https://www.ensembl.org/id/ENSGALG00010012699" } ] } } ], "crossref": [ { "id": "A0A8V0YGH2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YGH2", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd02122", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02122", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd16802", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16802", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "422382", "url": "https://www.ncbi.nlm.nih.gov/gene/422382", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001841", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001841", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003137", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003137", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046450", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046450", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051073", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051073", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:422382", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422382", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "NKSRFFW", "url": "https://omabrowser.org/oma/group/NKSRFFW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YFE5", "url": "https://www.orthodb.org/?gene=A0A8V0YFE5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YGH2", "url": "https://www.orthodb.org/?gene=A0A8V0YGH2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16200", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16200", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02225", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02225", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13639", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13639", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_040526712", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040526712", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YFE5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFE5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YFE5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFE5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YGH2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGH2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YGH2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGH2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASGAAGLLAAVAALLCVVPEPGVGAAAAVWTAWLNVSWEDGAGGNRSGWEAGESGLYGQDSPLQAAAGLLVLPDGRDAFNACSALTNFSAAPPGGGPGWVALIQRGGGCSFADKIRLAAERGAAAAVIYNYRGTGNDVLPMSHAGAGSIVAIMIGNLKGMEILRRIESGLKVTMVIEVGKKHGPWMNHYSIFFVSVSFFIVTAATVGYFIFYSARRFRITRAQSRKQRQLKAEAKKAIGQLQLRTLKQGDKETGPDGDSCAVCIELYKPNEVVRILTCNHLFHKNCIDPWLLEHRTCPMCKCDILKVLGVEVDAEDGAESVQATVSSGTSNITSINEVDSHSETASSGYASVQGADESVLEEHAPSENDNTHLVNNESQTSAVTVLPPLDNPTFEADETQVSEVRS", "length": 407, "header": "tr|A0A8V0YGH2-1|A0A8V0YGH2_CHICK Isoform 1 of Ring finger protein 128 OS=Gallus gallus OX=9031 GN=RNF128 PE=4 SV=1 CANONICAL=A0A8V0YGH2-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YFE5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGH2/entry#A0A8V0YFE5-1", "sequence": { "sequence": "MKQENKFSPVCFLVIVGVLFRTTETTAERAFVSLLYFNSTSNRSASEQCECGLYGLNSPLLSAQGFVAIPKAASLQACDWNTQFTITEPPWIALIERGNCTFAEKIKVAARRGATAAVIYNAPAKRNYPIPMSHIGAGSIVAIMIGNLKGMEILRRIESGLKVTMVIEVGKKHGPWMNHYSIFFVSVSFFIVTAATVGYFIFYSARRFRITRAQSRKQRQLKAEAKKAIGQLQLRTLKQGDKETGPDGDSCAVCIELYKPNEVVRILTCNHLFHKNCIDPWLLEHRTCPMCKCDILKVLGVEVDAEDGAESVQATVSSGTSNITSINEVDSHSETASSGYASVQGADESVLEEHAPSENDNTHLVNNESQTSAVTVLPPLDNPTFEADETQVSEVRS", "length": 397, "header": "tr|A0A8V0YFE5-1|A0A8V0YGH2_CHICK Computationally mapped isoform of Ring finger protein 128 OS=Gallus gallus OX=9031 GN=RNF128 PE=4 SV=1 CANONICAL=A0A8V0YGH2-1" }, "locus": { "chromosome": "4", "start_pos": 17317664, "end_pos": 17281622, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030379.1", "url": "https://www.ensembl.org/id/ENSGALT00010030379.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017622.1", "url": "https://www.ensembl.org/id/ENSGALP00010017622.1" } ] } }, { "isoform_ac": "A0A8V0YGH2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGH2/entry#A0A8V0YGH2-1", "sequence": { "sequence": "MASGAAGLLAAVAALLCVVPEPGVGAAAAVWTAWLNVSWEDGAGGNRSGWEAGESGLYGQDSPLQAAAGLLVLPDGRDAFNACSALTNFSAAPPGGGPGWVALIQRGGGCSFADKIRLAAERGAAAAVIYNYRGTGNDVLPMSHAGAGSIVAIMIGNLKGMEILRRIESGLKVTMVIEVGKKHGPWMNHYSIFFVSVSFFIVTAATVGYFIFYSARRFRITRAQSRKQRQLKAEAKKAIGQLQLRTLKQGDKETGPDGDSCAVCIELYKPNEVVRILTCNHLFHKNCIDPWLLEHRTCPMCKCDILKVLGVEVDAEDGAESVQATVSSGTSNITSINEVDSHSETASSGYASVQGADESVLEEHAPSENDNTHLVNNESQTSAVTVLPPLDNPTFEADETQVSEVRS", "length": 407, "header": "tr|A0A8V0YGH2-1|A0A8V0YGH2_CHICK Isoform 1 of Ring finger protein 128 OS=Gallus gallus OX=9031 GN=RNF128 PE=4 SV=1 CANONICAL=A0A8V0YGH2-1" }, "locus": { "chromosome": "4", "start_pos": 17317664, "end_pos": 17291605, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030376.1", "url": "https://www.ensembl.org/id/ENSGALT00010030376.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017620.1", "url": "https://www.ensembl.org/id/ENSGALP00010017620.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:422382", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422382", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2QK34-1", "protein_name": "E3 ubiquitin-protein ligase RNF128 isoform X2", "gene_name": "Rnf128", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MGPPPGTRVTCRGACGAARLLAWCFLLALSPHAPGSRGAEAVWTAYLNVSWRVPHTGVNRTVWELSEEGVYGQDSPLEPVSGVLVPPDGPGALNACNPHTNFTVPTMQVSWLALIQRGGGCTFADKIHLAYERGASGAVIFNFPGTRNEVIPMSHPGAGDIVAIMIGNLKGTKILQSIQRGIQVTMVIEVGKKHGPWVNHYSIFFVSVSFFIITAATVGYFIFYSARRLRNARAQSRKQRQLKADAKKAIGKLQLRTLKQGDKEIGPDGDSCAVCIELYKPNDLVRILTCNHIFHKTCVDPWLLEHRTCPMCKCDILKALGIEVDVEDGSVSLQVPVSNDASNTASPHEEDNRSETASSGYASVQGADEPPLEEHVQSANENLQLVNHEASSVAVDVVPHVDNPTFEEDESPNEETAVREIKS", "length": 423 }, "evidence": [ { "id": "A0A8V0YGH2", "url": "https://omabrowser.org/oma/group/A0A8V0YGH2/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0AAA9S6S6-1", "protein_name": "Ring finger protein 128", "gene_name": "RNF128", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGQLPGAGVFCRGGCGFSRLLAWCFLLVLSPQTPGSRGAEAVWTAYLNVSWRVPHTGVNRTVWELSEEGVYGQDSPLEPVAGVLVPPDGPGALNACNPHTNFTVPTVPGDWGSSVQVSWLALIQRGGGCTFADKIHLAYERGASGAVIFNFPGTRNEVIPMSHPGAGDIVAIMIGNLKGTKILQSIQRGIQVTMVIEVGKKHGPWVNHYSIFFVSVSFFIITAATVGYFIFYSARRLRNARAQSRKQRQLKADAKKAIGRLQLRTLKQGDKEIGPDGDSCAVCIELYKPNDLVRILTCNHVFHKTCVDPWLLEHRTCPMCKCDILKALGIEVDVEDGSVSLQVPVSNETSSNASPHEEDNRSETASSGYASVQGADEPPLEEHAHSAIQLWPLVIIIMLRWRQQPTPVFLPGESNGWRSLAGYSPWDHKSRT", "length": 432 }, "evidence": [ { "id": "A0A8V0YGH2", "url": "https://omabrowser.org/oma/group/A0A8V0YGH2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "I3LEX1-1", "protein_name": "Ring finger protein 128", "gene_name": "RNF128", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MNQENKSSRFRLLLVFTVLFKITAPFSMNAYVTVTYYNETSNDTSTETCECGVYGLASPVADAVGVVGIPKNNNYQACDYNTEFTNTKKPWIALIERGNCTFSEKIQTAGRRNADAVVIYNVPETGNQTIQMANFGAGDIVAIMIGNLKGTKILQSIQRGIQVTMVIEVGKKHGPWVNHYSIFFVSVSFFIITAATVGYFIFYSARRLRNARAQSRKQRQLKADAKKAIGRLQLRTLKQGDKEIGPDGDSCAVCIELYKPNDLVRILTCNHIFHKTCVDPWLLEHRTCPMCKCDILKALGIEVDVEDGSVSLQVPVSNETSNSASPHEEDNRSETASSGYASVQGADEPPLEEHVQSANENLQLVNHEASSMAVDVVPHVDNPTFEEDETPGQETAVREIKS", "length": 402 }, "evidence": [ { "id": "A0A8V0YGH2", "url": "https://omabrowser.org/oma/group/A0A8V0YGH2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q8TEB7-1", "protein_name": "E3 ubiquitin-protein ligase RNF128", "gene_name": "RNF128", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGPPPGAGVSCRGGCGFSRLLAWCFLLALSPQAPGSRGAEAVWTAYLNVSWRVPHTGVNRTVWELSEEGVYGQDSPLEPVAGVLVPPDGPGALNACNPHTNFTVPTVWGSTVQVSWLALIQRGGGCTFADKIHLAYERGASGAVIFNFPGTRNEVIPMSHPGAVDIVAIMIGNLKGTKILQSIQRGIQVTMVIEVGKKHGPWVNHYSIFFVSVSFFIITAATVGYFIFYSARRLRNARAQSRKQRQLKADAKKAIGRLQLRTLKQGDKEIGPDGDSCAVCIELYKPNDLVRILTCNHIFHKTCVDPWLLEHRTCPMCKCDILKALGIEVDVEDGSVSLQVPVSNEISNSASSHEEDNRSETASSGYASVQGTDEPPLEEHVQSTNESLQLVNHEANSVAVDVIPHVDNPTFEEDETPNQETAVREIKS", "length": 428 }, "evidence": [ { "id": "A0A8V0YGH2", "url": "https://omabrowser.org/oma/group/A0A8V0YGH2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9D304-1", "protein_name": "E3 ubiquitin-protein ligase RNF128", "gene_name": "Rnf128", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGPPPGIGVYCRGGCGAARLLAWCFLLALSPHAPGSRGAEAVWTAYLNVSWRVPHTGVNRTVWELSEEGVYGQDSPLEPVSGVLVPPDGPGALNACNPHTNFTVPTVWGSTVQVSWLALIQRGGGCTFADKIHLASERGASGAVIFNFPGTRNEVIPMSHPGAGDIVAIMIGNLKGTKILQSIQRGIQVTMVIEVGKKHGPWVNHYSIFFVSVSFFIITAATVGYFIFYSARRLRNARAQSRKQRQLKADAKKAIGKLQLRTLKQGDKEIGPDGDSCAVCIELYKPNDLVRILTCNHIFHKTCVDPWLLEHRTCPMCKCDILKALGIEVDVEDGSVSLQVPVSNEASNTASPHEEDSRSETASSGYASVQGADEPPLEEHAQSANENLQLVNHEANSVAVDVVPHVDNPTFEEDETPDQEAAVREIKS", "length": 428 }, "evidence": [ { "id": "A0A8V0YGH2", "url": "https://omabrowser.org/oma/group/A0A8V0YGH2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGH2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGH2" } ], "pmid": "" }, { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGH2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGH2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGH2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGH2" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGH2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGH2" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGH2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGH2" } ], "pmid": "" }, { "name": "late 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"count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YFF7-1", "uniprot_ac": "A0A8V0YFF7", "uniprot_id": "A0A8V0YFF7_CHICK", "mass": { "chemical_mass": 19900.0, "monoisotopic_mass": 19900.0 }, "refseq": {}, "gene_names": [ { "name": "ZCCHC10", "type": "recommended", "evidence": [ { "id": "A0A8V0YFF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFF7" } ] } ], "protein_names": [ { "name": "Zinc finger CCHC-type containing 10", "type": "synonym", "evidence": [ { "id": "A0A8V0YFF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFF7/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFF7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFF7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ZCCHC10", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFF7", "locus": { "chromosome": 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"database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13491", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13491", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13491:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13491:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13917", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13917", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YFF7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFF7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YFF7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFF7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLC6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLC6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLC6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLC6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLD2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLD2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLD2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLD2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "EEPRSGRRAAEARWSPPVGRCSAVRGAGWREANKQHVRCQKCLEFGHWTYECTGKRKYLHRPSRTAQLAKILKEKEKQLLLQQSTGESTAERKTKKKRSKSVTSSSSSSSDSSASDSSSDSDDSSTSSSSDSDSDESSSTSSSSPSSSSTSSSSEFESDSSSSSSSSSSTDSSSDDEPPKKKKKK", "length": 185, "header": "tr|A0A8V0YFF7-1|A0A8V0YFF7_CHICK Isoform 1 of Zinc finger CCHC-type containing 10 OS=Gallus gallus OX=9031 GN=ZCCHC10 PE=4 SV=1 CANONICAL=A0A8V0YFF7-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YFF7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFF7/entry#A0A8V0YFF7-1", "sequence": { "sequence": "EEPRSGRRAAEARWSPPVGRCSAVRGAGWREANKQHVRCQKCLEFGHWTYECTGKRKYLHRPSRTAQLAKILKEKEKQLLLQQSTGESTAERKTKKKRSKSVTSSSSSSSDSSASDSSSDSDDSSTSSSSDSDSDESSSTSSSSPSSSSTSSSSEFESDSSSSSSSSSSTDSSSDDEPPKKKKKK", "length": 185, "header": "tr|A0A8V0YFF7-1|A0A8V0YFF7_CHICK Isoform 1 of Zinc finger CCHC-type containing 10 OS=Gallus gallus OX=9031 GN=ZCCHC10 PE=4 SV=1 CANONICAL=A0A8V0YFF7-1" }, "locus": { "chromosome": "13", "start_pos": 16745757, "end_pos": 16737357, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033106.1", "url": "https://www.ensembl.org/id/ENSGALT00010033106.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019571.1", "url": "https://www.ensembl.org/id/ENSGALP00010019571.1" } ] } }, { "isoform_ac": "A0A8V0YLC6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFF7/entry#A0A8V0YLC6-1", "sequence": { "sequence": "WGLIAKPCAEENPTLWFIDAEEANKQHVRCQKCLEFGHWTYECTGKRKYLHRPSRTAQLAKILKEKEKQLLLQQSTGESTAERKTKKKRSKSVTSSSSSSSDSSASDSSSDSDDSSTSSSSDSDSDESSSTSSSSPSSSSTSSSSEFESDSSSSSSSSSSTDSSSDDEPPKKKKKK", "length": 176, "header": "tr|A0A8V0YLC6-1|A0A8V0YLC6_CHICK Computationally mapped isoform of Zinc finger CCHC-type containing 10 OS=Gallus gallus OX=9031 GN=ZCCHC10 PE=4 SV=1 CANONICAL=A0A8V0YFF7-1" }, "locus": { "chromosome": "13", "start_pos": 16745188, "end_pos": 16737357, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033100.1", "url": "https://www.ensembl.org/id/ENSGALT00010033100.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019570.1", "url": "https://www.ensembl.org/id/ENSGALP00010019570.1" } ] } }, { "isoform_ac": "A0A8V0YLD2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFF7/entry#A0A8V0YLD2-1", "sequence": { "sequence": "MQRGASHFPAVKMATPMHRLIARRQAEANKQHVRCQKCLEFGHWTYECTGKRKYLHRPSRTAQLAKILKEKEKQLLLQQRSKSVTSSSSSSSDSSASDSSSDSDDSSTSSSSDSDSDESSSTSSSSPSSSSTSSSSEFESDSSSSSSSSSSTDSSSDDEPPKKKKKK", "length": 167, "header": "tr|A0A8V0YLD2-1|A0A8V0YLD2_CHICK Computationally mapped isoform of Zinc finger CCHC-type containing 10 OS=Gallus gallus OX=9031 GN=ZCCHC10 PE=4 SV=1 CANONICAL=A0A8V0YFF7-1" }, "locus": { "chromosome": "13", "start_pos": 16745917, "end_pos": 16737357, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033112.1", "url": "https://www.ensembl.org/id/ENSGALT00010033112.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019575.1", "url": "https://www.ensembl.org/id/ENSGALP00010019575.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFF7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFF7" } ], "pmid": "" }, { "name": "nucleic acid binding", "id": "GO:0003676", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003676", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFF7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFF7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YFF9-1", "uniprot_ac": "A0A8V0YFF9", "uniprot_id": "A0A8V0YFF9_CHICK", "mass": { "chemical_mass": 359428.0, "monoisotopic_mass": 359428.0 }, "refseq": { "ac": "XP_003640413", "name": "cilia- and flagella-associated protein 54 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003640413" }, "gene_names": [ { "name": "CFAP54", "type": "recommended", "evidence": [ { "id": "A0A8V0YFF9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFF9" } ] }, { "name": "CFAP54", "type": "synonym", "evidence": [ { "id": "XP_003640413", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003640413" } ] } ], "protein_names": [ { "name": "Cilia and flagella associated protein 54", "type": "synonym", "evidence": [ { "id": "A0A8V0YFF9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFF9/entry#names_and_taxonomy" } ] }, { "name": "cilia- and flagella-associated protein 54 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_003640413", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003640413" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_003640413.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003640413", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003640413" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFF9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFF9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CFAP54", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFF9", "locus": { "chromosome": "1", "start_pos": 46057526, "end_pos": 45946445, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010011960", "url": "https://www.ensembl.org/id/ENSGALG00010011960" } ] } } ], "crossref": [ { "id": "417921", "url": "https://www.ncbi.nlm.nih.gov/gene/417921", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR027912", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027912", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:417921", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417921", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "FTELNIM", "url": "https://omabrowser.org/oma/group/FTELNIM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YBY8", "url": "https://www.orthodb.org/?gene=A0A8V0YBY8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YFF9", "url": "https://www.orthodb.org/?gene=A0A8V0YFF9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR33487", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR33487", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR33487:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR33487:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF14858", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14858", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003640413", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003640413", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YBY8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBY8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YBY8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBY8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YFF9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFF9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YFF9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFF9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAEPAEPPPPAPVPRPAAFFGAVAPGNPVVDSLEAELRDVVRFLRRLRGTGEAEPHWHELHRRGANTLFNIWIKYKPRLPDWYYNDKLLKVGDSLAQIKEYKLALTQCYGRYLQQFCSVNPDDITDDENQFKSTFFPNGFRDKNAALTFHALQERNVCVYQMVCNSDRNLQKQESLQTCFKVLSSLRLTMQMALPQQNLCWLIYNGTIHIYMICRHLMMIGQSAKVLEYLLWASICMELSIPLLSVHYLTWRATLYAAVSQCYFDCQAGIHGEVFARRGLIQINELKQLENISSSQKSSETGKIFREATIKMSVMIFKRAVYESRRKPKSYFRPKLRVNLKEAQNLPWPRTTTEQLLMEMFDGTASQFLAILEALSDSSRRVLHPTPPVPDEPEIRDVISELFFAGLEILSGGVSSTDVQGDDCTDKFGIINASSTLLQLILTGEKRVSGEAAVKFAKLAFNYEEWDVFDSAIVFVTNFLQAQNDPRWKKAEVELKLLTLMKPLLFPRKFRHGFSVSENNTKGDHMPRVSDKKRTVRSSLKCGEPSHDLIILATTVFSYVSTSKQNILPDKEILFDVITFLWQKCKTGLQLIQINGIGNFKYNHKYKASKWVYVLWIINEVILQSNVADTDVVMVAEITLCLTAILENMADSASKSKKKAGKRSVILSEDDSCDIPEILMRSPTEQLQLAYEYLEKTINEMNKSRLMTFLPDGKSILDDCCTKVDSHGQNLSSVLEWSNDKTRTGNSFLMDLHLELIQAQHRIAVKLLKMTQSVQKDGKSLKSSKYHVKNNEDSHYLTEADIMGKIKKNKLSRAIFLMEKAVQMFPKDLSTSSQRQLLKEALTLIEQVEAEQSALYHSLKEFMSSKKKSKIPPPPLLLSRSHCSMTFKPASFSSDVQVAWYSILGCVAGESNTKVRLNNNKLPNAGEEILADGKSLLEVQGLDPNEKYIFAVAAYSSDGKLIGDAIGETTRPILAYPPLSATTVRAYLTQVAYQTGNYTLARGAFSPMWDYFVSNSSPLPTNAAVISARSTLTISEKRLRFEAVSQTSPITLYLFLRNIFAICDINITEGALFCDSICCDEILYKEQVGRLAECERMTVAIELSNFLNDASYALQAVVQCYGLLAPIIYHKISAVPVVQILIKCLAILQEIPSATLQRRQAGCYESIQHMIACTSFYTAKVLRSWKEYELAVIIINYGKNLLDSSQTTATGQPGATETEETHKIKNISAKTSHLAAMEKATENLSALESNLLRLTQPARGSKLAGQEDPLFLYPIISCWTSNTAYREVMKFRNKSRFLEFFIQVLHKILNEEKFHSVLEWAENVQTFLKRRNNHILGISETPRQKTSSPSEPEGTKKYTVGVKEFQKSTKTSPVKKQKAPALKKKGKETPSPTRKRQTLRQYFMKHPNIMKSPEAQRKHKEELQKVAHNTLVVLLKPAVSNYLNRKKFHQICLEEMPWKSQMNIYLANAHYNLFKKKLEEQYNIGICGFHHQDSYNILDPEIFSLNNSGTVVVREAVENNRRTSNPLKSPSELTKKQTYTDRSSQHSTKLWGRDTPQTQMTNDMEISISLSPKECRQFPSYTILLDHFTKIFLHLRRAAVLAHRGGHWTLLQNACRELWNYTQESQSISNRSHSQKDAFPITREFLRNTVWLPFYLASDMIIDMITELQASNSLKIVEPEGDFCIPSCLGGITDENGGSNLHPQSPLDDVNVVDLKWICNLILKTLEFLYQMKKWEALVHIALQFNVFTHERYTEQVSPLLVYAQRQLLERIQQFGGPGSHESNFTKYLSDNANKLSCRDYIGQNLQLPVARSASILVFPGCFFCPEMKNDYADGSQAKPIVYVPLDVKDALQCFRESLKKSKYHSRALKHSRKLLSLFLAYTQEVVGRTISQISPDRRLEFNVGAELAFLPTPSDLSQEKFNFSSSIERKPIPQSQLSLIVSSYEQTIEILEVNNQRDLKVQALHELGNLHFYAGNKRAAFKYWCQALDETLNTDDILNTWQELGFPKNATECFAVGRSTDICQKFLSQAGIWGCLHAAVLVAKIAQYITTSNVRLRTRYCQFSAILFKSLFRASLPHPTSDCDFAQYETQMLIPGIDLFSDRYRADISTVVASLNFLMFELHCAKQNLTILPLFTLYQYFISEICKDPAKCIEGRIFKIKVLTDIGFFTEAFHELCLLNCGERIPWKIPAGYKINEEIKTLLYFDSSKSLLSFTNLQVLEDIFNWSLSLTVVPLCNQQIMNKLILAKMHFIICLSATINNVPEKVEKCIYSVDNMPDGNTPSNVKVDAVKNFRQREQRDTVMQLIDCEAELNMAMLKGILLQEAEESLNCLVQNIQDKYDGKIYHCSAEDLEVLTEAKLQLAAISQQWHRAALSVALAFSAIRLLQDADIFRMTATNFQEEKDKRDSLDSCVEDAQQPHSTIAQDHLNVRLWLRCRKMLVTALATQLHSVGDKEENNVAERRSIVKEVILEAEAFGDTETQAEMMVQAAILDLQEGCPMADIKILLQNIISLLQEDKFISPPASLTLVKSMLLMTDILALQTIENMEYCSAVDPLNLLNLAHDITLKEIFSCGEYIEQQIEDSTLTCLVLPAKNIYLPYINLLAQVKMRIGNTLAERVACTPEREDPLQWLHALKHLETALKLCRASATEVLDMEAQLLFQIGKVECQIAKAGNNKPYQAVETLLEAIKLSQQHDQNFELIRRSYLEIALLYLHFATNNENLSQRDKTVPSKSEISAGELSSSPGETLKSEGYKVRAWIAVRAARQVSEAVVASQLLIGMESIKEHNVKDALQQKIPEFASMDLLASYRDYLSDEYNVVCGSHTASSTENKQTIQEDQNQNEGMECLDTSSNQKKEIITWVHLIRYHSYIEGLCHTNLFAAHKSGLGSLSGRDGHLNSLCDSWVVLRVAEMHSFLKKHLLEYSVCCLESFPEQLRDLEVSRGCSPDSPKTSLEDSGISPKVSCVKIASQVSVVAEAGSHMESRAANASNKEISIQWYIPSLAKPANGADTKVLLLYAYNTQPVKISNVKFFSSMSVFSGQLWIPLARIISLREKLSNLKHQVEMLMQSLGNSPAAEPTSFLEQNEALKTTPSEEAEMNIARVHLDEKTEEMATRCLSEVKALLSAVPVLALTLTEIPFDINLQSIASLEDMFDLANGCTITEESLFSWIISLFH", "length": 3176, "header": "tr|A0A8V0YFF9-1|A0A8V0YFF9_CHICK Isoform 1 of Cilia and flagella associated protein 54 OS=Gallus gallus OX=9031 GN=CFAP54 PE=4 SV=1 CANONICAL=A0A8V0YFF9-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YBY8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFF9/entry#A0A8V0YBY8-1", "sequence": { "sequence": "MHSHCLPNDSVHMSSLSWLLVPSSPCHMILVGQWRHTALRGANTLFNIWIKYKPRLPDWYYNDKLLKVGDSLAQIKEYKLALTQCYGRYLQQFCSVNPDDITDDENQFKSTFFPNGFRDKNAALTFHALQERNVCVYQMVCNSDRNLQKQESLQTCFKVLSSLRLTMQMALPQQNLCWLIYNGTIHIYMICRHLMMIGQSAKVLEYLLWASICMELSIPLLSVHYLTWRATLYAAVSQCYFDCQAGIHGEVFARRGLIQINELKQLENISSSQKSSETGKIFREATIKMSVMIFKRAVYESRRKPKSYFRPKLRVNLKEAQNLPWPRTTTEQLLMEMFDGTASQFLAILEALSDSSRRVLHPTPPVPDEPEIRDVISELFFAGLEILSGGVSSTDVQGDDCTDKFGIINASSTLLQLILTGEKRVSGEAAVKFAKLAFNYEEWDVFDSAIVFVTNFLQAQNDPRWKKAEVELKLLTLMKPLLFPRKFRHGFSVSENNTKGDHMPRVSDKKRTVRSSLKCGEPSHDLIILATTVFSYVSTSKQNILPDKEILFDVITFLWQKCKTGLQLIQINGIGNFKYNHKYKASKWVYVLWIINEVILQSNVADTDVVMVAEITLCLTAILENMADSASKSKKKAGKRSVILSEDDSCDIPEILMRSPTEQLQLAYEYLEKTINEMNKSRLMTFLPDGKSILDDCCTKVDSHGQNLSSVLEWSNDKTRTGNSFLMDLHLELIQAQHRIAVKLLKMTQSVQKDGKSLKSSKYHVKNNEDSHYLTEADIMGKIKKNKLSRAIFLMEKAVQMFPKDLSTSSQRQLLKEALTLIEQVEAEQSALYHSLKEFMSSKKKSKIPPPPLLLSRSHCSMTFKPASFSSDVQVAWYSILGCVAGESNTKVRLNNNKLPNAGEEILADGKSLLEVQGLDPNEKYIFAVAAYSSDGKLIGDAIGETTRPILAYPPLSATTVRAYLTQVAYQTGNYTLARGAFSPMWDYFVSNSSPLPTNAAVISARSTLTISEKRLRFEAVSQTSPITLYLFLRNIFAICDINITEGALFCDSICCDEILYKEQVGRLAECERMTVAIELSNFLNDASYALQAVVQCYGLLAPIIYHKISAVPVVQILIKCLAILQEIPSATLQRRQAGCYESIQHMIACTSFYTAKVLRSWKEYELAVIIINYGKNLLDSSQTTATGQPGATETEETHKIKNISAKTSHLAAMEKATENLSALESNLLRLTQPARGSKLAGQEDPLFLYPIISCWTSNTAYREVMKFRNKSRFLEFFIQVLHKILNEEKFHSVLEWAENVQTFLKRRNNHILGISETPRQKTSSPSEPEGTKKYTVGVKEFQKSTKTSPVKKQKAPALKKKGKETPSPTRKRQTLRQYFMKHPNIMKSPEAQRKHKEELQKVAHNTLVVLLKPAVSNYLNRKKFHQICLEEMPWKSQMNIYLANAHYNLFKKKLEEQYNIGICGFHHQDSYNILDPEIFSLNNSGTVVVREAVENNRRTSNPLKSPSELTKKQTYTDRSSQHSTKLWGRDTPQTQMTNDMEISISLSPKECRQFPSYTILLDHFTKIFLHLRRAAVLAHRGGHWTLLQNACRELWNYTQESQSISNRSHSQKDAFPITREFLRNTVWLPFYLASDMIIDMITELQASNSLKIVEPEGDFCIPSCLGGITDENGGSNLHPQSPLDDVNVVDLKWICNLILKTLEFLYQMKKWEALVHIALQFNVFTHERYTEQVSPLLVYAQRQLLERIQQFGGPGSHESNFTKYLSDNANKLSCRDYIGQNLQLPVARSASILVFPGCFFCPEMKNDYADGSQAKPIVYVPLDVKDALQCFRESLKKSKYHSRALKHSRKLLSLFLAYTQEVVGRTISQISPDRRLEFNVGAELAFLPTPSDLSQEKFNFSSSIERKPIPQSQLSLIVSSYEQTIEILEVNNQRDLKVQALHELGNLHFYAGNKRAAFKYWCQALDETLNTDDILNTWQELGFPKNATECFAVGRSTDICQKFLSQAGIWGCLHAAVLVAKIAQYITTSNVRLRTRYCQFSAILFKSLFRASLPHPTSDCDFAQYETQMLIPGIDLFSDRYRADISTVVASLNFLMFELHCAKQNLTILPLFTLYQYFISEICKDPAKCIEGRIFKIKVLTDIGFFTEAFHELCLLNCGERIPWKIPAGYKINEEIKTLLYFDSSKSLLSFTNLQVLEDIFNWSLSLTVVPLCNQQIMNKLILAKMHFIICLSATINNVPEKVEKCIYSVDNMPDGNTPSNVKVDAVKNFRQREQRDTVMQLIDCEAELNMAMLKGILLQEAEESLNCLVQNIQDKYDGKIYHCSAEDLEVLTEAKLQLAAISQQWHRAALSVALAFSAIRLLQDADIFRMTATNFQEEKDKRDSLDSCVEDAQQPHSTIAQDHLNVRLWLRCRKMLVTALATQLHSVGDKEENNVAERRSIVKEVILEAEAFGDTETQAEMMVQAAILDLQEGCPMADIKILLQNIISLLQEDKFISPPASLTLVKSMLLMTDILALQTIENMEYCSAVDPLNLLNLAHDITLKEIFSCGEYIEQQIEDSTLTCLVLPAKNIYLPYINLLAQVKMRIGNTLAERVACTPEREDPLQWLHALKHLETALKLCRASATEVLDMEAQLLFQIGKVECQIAKAGNNKPYQAVETLLEAIKLSQQHDQNFELIRRSYLEIALLYLHFATNNENLSQRDKTVPSKSEISAGELSSSPGETLKSEGYKVRAWIAVRAARQVSEAVVASQLLIGMESIKEHNVKDALQQKIPEFASMDLLASYRDYLSDEYNVVCGSHTASSTENKQTIQEDQNQNEGMECLDTSSNQKKEIITWVHLIRYHSYIEGLCHTNLFAAHKSGLGSLSGRDGHLNSLCDSWVVLRVAEMHSFLKKHLLEYSVCCLESFPEQLRDLEVSRGCSPDSPKTSLEDSGISPKVSCVKIASQVSVVAEAGSHMESRAANASNKEISIQWYIPSLAKPANGADTKVLLLYAYNTQPVKISNVKFFSSMSVFSGQLWIPLARIISLREKLSNLKHQVEMLMQSLGNSPAAEPTSFLEQNEALKTTPSEEAEMNIARVHLDEKTEEMATRCLSEVKALLSAVPVLALTLTEIPFDINLQSIASLEDMFDLANGCTITEESLFSWIISLFH", "length": 3153, "header": "tr|A0A8V0YBY8-1|A0A8V0YBY8_CHICK Computationally mapped isoform of Cilia and flagella associated protein 54 OS=Gallus gallus OX=9031 GN=CFAP54 PE=4 SV=1 CANONICAL=A0A8V0YFF9-1" }, "locus": { "chromosome": "1", "start_pos": 46057440, "end_pos": 45952463, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028661.1", "url": "https://www.ensembl.org/id/ENSGALT00010028661.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016472.1", "url": "https://www.ensembl.org/id/ENSGALP00010016472.1" } ] } }, { "isoform_ac": "A0A8V0YFF9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFF9/entry#A0A8V0YFF9-1", "sequence": { "sequence": "MAEPAEPPPPAPVPRPAAFFGAVAPGNPVVDSLEAELRDVVRFLRRLRGTGEAEPHWHELHRRGANTLFNIWIKYKPRLPDWYYNDKLLKVGDSLAQIKEYKLALTQCYGRYLQQFCSVNPDDITDDENQFKSTFFPNGFRDKNAALTFHALQERNVCVYQMVCNSDRNLQKQESLQTCFKVLSSLRLTMQMALPQQNLCWLIYNGTIHIYMICRHLMMIGQSAKVLEYLLWASICMELSIPLLSVHYLTWRATLYAAVSQCYFDCQAGIHGEVFARRGLIQINELKQLENISSSQKSSETGKIFREATIKMSVMIFKRAVYESRRKPKSYFRPKLRVNLKEAQNLPWPRTTTEQLLMEMFDGTASQFLAILEALSDSSRRVLHPTPPVPDEPEIRDVISELFFAGLEILSGGVSSTDVQGDDCTDKFGIINASSTLLQLILTGEKRVSGEAAVKFAKLAFNYEEWDVFDSAIVFVTNFLQAQNDPRWKKAEVELKLLTLMKPLLFPRKFRHGFSVSENNTKGDHMPRVSDKKRTVRSSLKCGEPSHDLIILATTVFSYVSTSKQNILPDKEILFDVITFLWQKCKTGLQLIQINGIGNFKYNHKYKASKWVYVLWIINEVILQSNVADTDVVMVAEITLCLTAILENMADSASKSKKKAGKRSVILSEDDSCDIPEILMRSPTEQLQLAYEYLEKTINEMNKSRLMTFLPDGKSILDDCCTKVDSHGQNLSSVLEWSNDKTRTGNSFLMDLHLELIQAQHRIAVKLLKMTQSVQKDGKSLKSSKYHVKNNEDSHYLTEADIMGKIKKNKLSRAIFLMEKAVQMFPKDLSTSSQRQLLKEALTLIEQVEAEQSALYHSLKEFMSSKKKSKIPPPPLLLSRSHCSMTFKPASFSSDVQVAWYSILGCVAGESNTKVRLNNNKLPNAGEEILADGKSLLEVQGLDPNEKYIFAVAAYSSDGKLIGDAIGETTRPILAYPPLSATTVRAYLTQVAYQTGNYTLARGAFSPMWDYFVSNSSPLPTNAAVISARSTLTISEKRLRFEAVSQTSPITLYLFLRNIFAICDINITEGALFCDSICCDEILYKEQVGRLAECERMTVAIELSNFLNDASYALQAVVQCYGLLAPIIYHKISAVPVVQILIKCLAILQEIPSATLQRRQAGCYESIQHMIACTSFYTAKVLRSWKEYELAVIIINYGKNLLDSSQTTATGQPGATETEETHKIKNISAKTSHLAAMEKATENLSALESNLLRLTQPARGSKLAGQEDPLFLYPIISCWTSNTAYREVMKFRNKSRFLEFFIQVLHKILNEEKFHSVLEWAENVQTFLKRRNNHILGISETPRQKTSSPSEPEGTKKYTVGVKEFQKSTKTSPVKKQKAPALKKKGKETPSPTRKRQTLRQYFMKHPNIMKSPEAQRKHKEELQKVAHNTLVVLLKPAVSNYLNRKKFHQICLEEMPWKSQMNIYLANAHYNLFKKKLEEQYNIGICGFHHQDSYNILDPEIFSLNNSGTVVVREAVENNRRTSNPLKSPSELTKKQTYTDRSSQHSTKLWGRDTPQTQMTNDMEISISLSPKECRQFPSYTILLDHFTKIFLHLRRAAVLAHRGGHWTLLQNACRELWNYTQESQSISNRSHSQKDAFPITREFLRNTVWLPFYLASDMIIDMITELQASNSLKIVEPEGDFCIPSCLGGITDENGGSNLHPQSPLDDVNVVDLKWICNLILKTLEFLYQMKKWEALVHIALQFNVFTHERYTEQVSPLLVYAQRQLLERIQQFGGPGSHESNFTKYLSDNANKLSCRDYIGQNLQLPVARSASILVFPGCFFCPEMKNDYADGSQAKPIVYVPLDVKDALQCFRESLKKSKYHSRALKHSRKLLSLFLAYTQEVVGRTISQISPDRRLEFNVGAELAFLPTPSDLSQEKFNFSSSIERKPIPQSQLSLIVSSYEQTIEILEVNNQRDLKVQALHELGNLHFYAGNKRAAFKYWCQALDETLNTDDILNTWQELGFPKNATECFAVGRSTDICQKFLSQAGIWGCLHAAVLVAKIAQYITTSNVRLRTRYCQFSAILFKSLFRASLPHPTSDCDFAQYETQMLIPGIDLFSDRYRADISTVVASLNFLMFELHCAKQNLTILPLFTLYQYFISEICKDPAKCIEGRIFKIKVLTDIGFFTEAFHELCLLNCGERIPWKIPAGYKINEEIKTLLYFDSSKSLLSFTNLQVLEDIFNWSLSLTVVPLCNQQIMNKLILAKMHFIICLSATINNVPEKVEKCIYSVDNMPDGNTPSNVKVDAVKNFRQREQRDTVMQLIDCEAELNMAMLKGILLQEAEESLNCLVQNIQDKYDGKIYHCSAEDLEVLTEAKLQLAAISQQWHRAALSVALAFSAIRLLQDADIFRMTATNFQEEKDKRDSLDSCVEDAQQPHSTIAQDHLNVRLWLRCRKMLVTALATQLHSVGDKEENNVAERRSIVKEVILEAEAFGDTETQAEMMVQAAILDLQEGCPMADIKILLQNIISLLQEDKFISPPASLTLVKSMLLMTDILALQTIENMEYCSAVDPLNLLNLAHDITLKEIFSCGEYIEQQIEDSTLTCLVLPAKNIYLPYINLLAQVKMRIGNTLAERVACTPEREDPLQWLHALKHLETALKLCRASATEVLDMEAQLLFQIGKVECQIAKAGNNKPYQAVETLLEAIKLSQQHDQNFELIRRSYLEIALLYLHFATNNENLSQRDKTVPSKSEISAGELSSSPGETLKSEGYKVRAWIAVRAARQVSEAVVASQLLIGMESIKEHNVKDALQQKIPEFASMDLLASYRDYLSDEYNVVCGSHTASSTENKQTIQEDQNQNEGMECLDTSSNQKKEIITWVHLIRYHSYIEGLCHTNLFAAHKSGLGSLSGRDGHLNSLCDSWVVLRVAEMHSFLKKHLLEYSVCCLESFPEQLRDLEVSRGCSPDSPKTSLEDSGISPKVSCVKIASQVSVVAEAGSHMESRAANASNKEISIQWYIPSLAKPANGADTKVLLLYAYNTQPVKISNVKFFSSMSVFSGQLWIPLARIISLREKLSNLKHQVEMLMQSLGNSPAAEPTSFLEQNEALKTTPSEEAEMNIARVHLDEKTEEMATRCLSEVKALLSAVPVLALTLTEIPFDINLQSIASLEDMFDLANGCTITEESLFSWIISLFH", "length": 3176, "header": "tr|A0A8V0YFF9-1|A0A8V0YFF9_CHICK Isoform 1 of Cilia and flagella associated protein 54 OS=Gallus gallus OX=9031 GN=CFAP54 PE=4 SV=1 CANONICAL=A0A8V0YFF9-1" }, "locus": { "chromosome": "1", "start_pos": 46057440, "end_pos": 45953419, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028647.1", "url": "https://www.ensembl.org/id/ENSGALT00010028647.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016461.1", "url": "https://www.ensembl.org/id/ENSGALP00010016461.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1913, "start_aa": "Thr", "end_pos": 1913, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1913", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 386, "start_aa": "Thr", "end_pos": 386, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr386", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:417921", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417921", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I5ZKH9-1", "protein_name": "Cilia and flagella associated protein 54", "gene_name": "Cfap54", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASSNNSSSSSEVSPGSETSVSPAQLPPTPPPTSTAVLKSPTESKSSSTIPPHWTRSEDLLPSAAFYGPLDGKNPLLASCEKEIRELLGFMKKNKALATSEEQKHEFRRRCATTLFNIWTKYAPRLPADYYNEKLLKVGDSLCQIKEYKLALLQCYGRYLQGFTTDFDFDENKEDVNQFKTVFFPNGFGDEMARLTFHALSGKNICNYQLVCQSDANLQNEESVRQCLQILSSFRLIMQVALPQEHLCWIIFNGTLYIYTICRKLMVIGQSSKALEFLLWASMCMESSVPLLSVRYLTWRATLYTAVCQCHYDCQNGIHGETFARRALAKIDELRQLELMSSSSSLETSRKYYREATIKMAVMIFKRGVFESRRKNKNVFRPKIRLNLKEAQSLPWPRTVTERLLDELLDSTSSRFLAVLEALFDSNRRVLQTGPLQTDEMELRDVVSELFMAGKELLLLSNVGANGKLDFPKTHLLEQLVERKNIISVGASVKFAKLAFTYEEWGLFESLAGQLIPFLQKQDSPKEKKAEKDLILLLAVEPLINVKKNKGLIFPLDNDKETQSIQSYLKHIAYEESCVRTTYTEDIFSLAAILHFCVCVPTKGIQPDKDIVVDIITLLWQKCKLGLQRLNIPKSDFTKYSHKISTNKWVYLLWQISEVVHCYKLEDLDIVMVAEITLRLSEILESLGNPKRKFRKSADLSAKKGPDELPGTSKGVPESLPILKRTPVEQLFYAYELLDRTIAGMNWNCMLTTLSDGSSVIDHCYVKDSHDVDGDTYKPIASNSYTMDLHLELIQAQHRIAVVLLDQLDALQIPTVSSNSSAKGWEKFKKARSTECFSELTVMKKIKKNTLSKAIYLMQKALLLFEKDTACETSWNLLTEAYALIEKVEAEQNALYSYQKYLESTKVKRSRVPPPPILLARTHCSVTLKPAPFLSDVKVSWYCILGCKAERSYSKVRLNNNHLPNSGEVIPADGRSFFEIKDLETNAKYIFALTAYSSSGKLIGDAIGETTKPILIYPPLSAVTARMYLTQVAYQISNYELAKKVFSPVWDYFVAPPPQDNQSVICLSNIMTITQRRFHSNILAETSSILLYLFLRNIFVMSDIKIKEENLFCDNIKGNEIFPAQQVARLVECENVLVALELSNFLNDANFALQAVTQCYGLLAPIIYHNIVLVPVIQILIKCIVVLQGIPSVVHSKKNISSFESIQHMIACCIFYITKILRSWKEYDLAIMLINYGKKMLDITSGCKSLFGIDQEETTEEGTCSKKTSKIKKSQQVLVPEKINEQLTFLETHLLKLTKQITFTELSGAEDPIFLYPVVLNWNVKGAVKEVMKFKQRPRFLEFFTQIMLKCMNDEKFHLMVEICGPVYDFLKRRNESLIGVKRIRYKETTVSRKMLKSPKKFKAIVIEIGRSSDLPRRRRKRKENLKDFFYKNPSIFDMAELERNKRTDVRKMAYRSLMDNLNPLILTYVKRKRFHQILLEELPWRAQMNLYLANAHFHMFLQKLTERSKIKLGSSHSNVSFRSCDPNLFSLFHSGTILPTAKLTVDSYKAMMDVFSASKKRKHNQPTDIDDLSALFNSKSDDTVVSKIKAQSTYDSDSQLGSGINIREKDRMLAWGLDHFVKIFLCCRRAMVLAYRGGYWTLLQNCCRVFWNFSRELQILLKQIMDVCKAFPISQDSFLCISVLPFYLGTELLIDMLIKLQSTNSIKPLEEKGEFSIPSCYGNIKSDNGGSSLTFEHPLDDVNVVDLKWIHDFVLKSLEVLYQVEKWEMLVSLAIQFNTISHERYTEQVTPLLVYAQRQLVLRIEEMEGPDLSHQACARYEAETGEKITCRNFIGKQIMIDRSTPKNLAELDGSSDPLKTLVLSEIKLAKQLVCVPIDVNDTLRCFRETLEKSNHHSRSVRHSRKLLSLFLAQTQGERGGISSPKFTPGKVEFCLGTEEVHMSTPPDLSQENFRIFSSVEKTKLPSSQLGLVISSFYQTIDVLQASNQRSLKVQTLHSLGSLLIFADKKRAAFKCWSQALDDIFRKPDVLHNWKEFGNSLPSATSSSSPPGFKDYSEEFLSKFGIWGCLQGAVISAKIAQFIKTTNVKERINCCILSALLFQSLLRTTLPHPKAERSYAQYEITQLLPGIELFSDKFRADICIVVASLYYVIRELHYAKYNLIVLPLLALYQYFVSVICQDLVRNLEARILKIEILIDLGLFSEAFYELSQIYQGKNMPCAIPAGYKATTRVKITQSFDSGKPLTSKDNMQALEELVNRGLPSVLVNLGSQHLLNKFNFVKSHFFISLAATVNCIPDNSPKIVYYPVIIDKSKPNTQNAKDNENSHAQLLRFRDDYTLNTIKSILLMEAEDKINSLLSETERQCNRPLYLSSVADLEIMVEARLHLAAIALQRFRPAYSTAIIYCTLKLLQDSKVFKKRLPEEPCSPTSPETSTTENKDDGEFLDPVSLNCREYFNIHLWLRCRLMLVTSFVAQIRGIGIMKESELTDCLSLINEVCTEAKSADDTEVLAELLMQAVVLGLQEKHFKADIIGKLQEIINLLEGSEFLSPRSWLTLAKSLILMDDLTKAEKFKKASSKENKLIFLNQAHRILIAQMLTFGETIEFPLSDADYASPLQPLKNIYLPHIMLLAKIKLRIGHTLAKQVYSSSKKKDIGKWLPVLHVFDMALKVCRATAAEENEVEAEILFQKGRIERQMLMEEKSPIAHVESFFEAIQISLRNDQNPGLLRDSYLEVALVYFYLKKPRKKTSVTVKPSPRRLSSFKEPVATQVEMYSSLAWIAIRAAAQVSESVLAINLLIGKKSTRTDKVNNITLPNIPEFAAADLLSSYTDYLLDNYQVVFQTSVSFACQNEDVYDCIDGRKRNLSKVDITWILLIRYYIHLQRINNMSKLLASATPDSGISLPDDTIITSLYNSELILRQKEVHIFLKNFLQLYASSCIDGFPKELLQGLENTISLEKVLFESSDKVHQDSSLQSDLSGKLAGSTSYTDISSEMAVQALNKELCFQWYIPPLDKPPKDTEPMVLLLYAYNLKPLVISDIKVPTGNNLYVGTSWIPLRRVIQIHEKLSSLAQIAEISLPSVPEVASQENIYESIDIEDKPIDTDLENIILHCCSEIEALFSLDKDKKPLPLTEVPFDVSLPAIFSLERLFDLANGCIVSVGSLFNWVVSIIS", "length": 3171 }, "evidence": [ { "id": "A0A8V0YFF9", "url": "https://omabrowser.org/oma/group/A0A8V0YFF9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8C6S9-1", "protein_name": "Cilia- and flagella-associated protein 54", "gene_name": "Cfap54", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASSRSSSSSSEESPDSETSVSPVHLPPTPPPTSTAVLKSPSESKSSSTDPPQCTHSEDSLPSAAFYGPLDSKNPLLASCEKEIRELLGFMKKKKALATSMEQKYEFHRRCATTLFNIWTKYAPRLPSNYYNEKLLKVGDSLCQIKEYKLALLQCYGRYLQEFIADFDEHKEDVNHFKTVFFPKGFGDETARLTFHALSGKNICNYQLVCESDANLQNEESVRQCLHILSSFRLIMQVALPQEHLCWIIFNGTLYIYTICRKLMVIGQSSKALEFLLWASMCMESSVPLLSIRYLTWRATLYTAVCQCHYDCQDGIHGEAFARRALAKIDELRQLELMSSSSSLETSRKYYREATIKMAVMIFKRGVFESRRKNKNVLRPKLRLNLKEAQSLPWPRTVTERLLDELLDSTSSRFLAVLEALSDSNRRILQTGPLVTDEMELRDVVSELFMAGKELLILSNVRSNGKLDFPQTSLLEHVVEKRNALSVGASVRFAKLAFTYEEWGLFESLAGQLIHFLQKQDNPQSKKAEKDLILLLAVEPLINVKRNRGLIFPLETDKETQSIENYLKHIACHESCMRTTFTEDTFSLAAILHFCVCVPTQGVLPDKDIVVDIIGLLWQRCKLGIQRLNIPKNDFAKYSHKISTNKWVYLLWQISEVIHCYKLEDLDIVMVAEITLRLSEILESLGSPKRKFKKSADLSAKKGPDELPGTSKGVPEILPILKRAPVEQLFYAYELLDKAIIGMSWKCMLTTLSDGSSVIDHCYVKDSQDVDGDTYKPIASNSYTMDLHLELIQAQHRIAVVLLDQLEVLQAPTVSTNTPAKGWEKVKKPRSTECFTELTVMKKIKKNKLSKAIYLMQKALLLFEKDAVCETSRNLLMEANALIEKVEAEQNALYSYQKFLGSSKIKKSRIPPPPILLARTHCSVTLKPAPFISEVKASWYCILGCKADGSYGKVRLNNNHLPNSGEAIPADGRSFFEIKGLETNAQYCFAIAAYSSSGKLIGDAIGETTKPILIYPPLSAVTARMYLTQVAYQIGNYEMAKKVFSPVWDYFVASPLPDEQSVICLSNIMTITQKRLHSNILADTSSILLYLFLRNIFVMSDIKIKEENLFCDNIKGNEIFPAQQVARLVECENVLVALELSNFLNDANFALQAVTQCYGLLAPIIYHNIVLVPVIQILIKCIVVLQGIPSIIHSKKNISSFESIQHMIACCIFYMTKILRSWKEYDLAIMLINYGKKMLDITSGCRSLFGIEQEETAEEGVCSKKTSRTKKPQQVLLPEKINEQLALLETHLLKTTKQINSAELSGSEDPIFLYPIVLNWTVKGAMKEVMKFKQRPRFLEFFTQIMLKCMNDEKFHLMVEISAPVYDFLKRRNESLIGVKRIKYKETVISRRALKSPSKFKAIVIEIGKSSDLTRRRRKKKKTLKDFFYKNPSIFDMAELDRNKRTDVRKMAYRSLSDNLNPLILTYVRRKRFHQILLEELPWRAQMNLYLANAHFHLFLQKLTERTKERLGSSYSSVSFRSCDPNLFSLFHSGTVLPTAKLTVDSYNAMMDALTVSKKKKHNQTTDTEDLSVLFNSKSDDNIPKMKTQTIYESDSQLGIGVNVREKDRTLVWGLDHFMKIFLCCRRAMVLAYRGGYWTLLQNCCRVFWNFSRELQILLKQTVASCKTFPVSQDNFLCICVLPFYLGAELLIDMLIKLQSTNSIKPFEERGEFSIPSCYGNIKSDNGGSSLIFEHPLDDVNVVDLRWIHDFVLKSLEVLYQVEKWETLVSLAIQFNIISHERYTEQVTPLLVYAQRQLVQRIKELNGPELSRQACARYEAENGEKITCRNFIGKRLKIDSSTPKNLAELQGSSEPLKTLITSEQRLAKQLVSVPLDVNDTLRCFRETLEKSKYHNRSVRHSRKLLSLFLAQTQDVLQTSNQRSLKVQSLHSLGSLLLFADKKRAAFKCWSQALDDIFRKPDVLHNWKEFGTSLPGAPSSSSPPGFKDYSEEFLSKFGIWGCLQAAMITAKIAQFIKTANVKKRINCCILSALLFQSLLRTTLPHPKAERNYAQYEITQLLPGIELFSDKFRADICSVIASLYYVIRELHYAKYNLIVLPLLALYQYFVSVICQDIVRNLEARILKIEILIDLGFFSEAFYELFQIYHGKNMPCAIPAGYKATMKVKITQSFDSGKPLTHKDNMQALEELINRGLPHILVNLGYQHLLNKFNFAKSHFFISLAATINCIPDPSPKIMYYQFITERSKPTPQNLKDNENSHGQFLRLRDDYNLNTIKSILLMEAEEKVNSLLSETEHQCHRPLYLSSVLELEIMVEARLHLAAIALQRYRPAYSTAILYSTLKLLQDSKVFKKKVPEESCSPTSPETSTTESKDDSEFLDPISLNSREYFNIHLWLRCRLMLVTSFIAQIRGIGIMKESELTDCLSLIDEVCTEAKSADDTEVLAEFLMQAVVLGLQEKHFKADIIQKLKEIISLLEGSEFLSPRSWLTLAKSLILMDDLTKAEKFKKASSKENKLIFLNQAHRILIAQMLTFGETIEFPLSDSDYASPLQPLKNIYLPHVMLLAKVKLRIGHTMAKQVCSSSKKKDISKWLPVLHMFDMALKVCKATAAEEYEVEAEILFQKGRIERQMLMEEKTSIAHIESFFEAIQISLKNDQNSGLIRDSYLEIALVYFYLKKPKRKASATTLKPLPRRHSSVKDPVATQTEMYSSLAWIAIRAAAQVSESVLGINLLIGKKRAMIDKVNNITLPNIPEFATVDLLSSYTDYLLENYQVVFQTSNSLMCENDDVYDCIDGRKRNLSKVDVTWILLIRYYIHLQRINNMSKLLASATPVSGISLPDDTLLTSLYNSELILRQKEMHLFLKRFLQLYSSSCIDGFPRELLQGLENISLEKVLFESSGKVHRDSSLQSDLSGKLTVCPSYTEISSEMAVQALNKELCFQWYIPPLDKPLKDSEPMVLLLYAYNLKPLRILDIKVSTGNSLYVGTSWIPLRSVIAVHQKLSNLAQIAEISLPSVPEVTSEENIYETIEPEDKPIDTDLENMILECCSEIEALFSNNKDKDNEPPPPMTKVPFDVSLPAIFSLERLFDLANGCIVSVGSLFNWMVSIIQ", "length": 3106 }, "evidence": [ { "id": "A0A8V0YFF9", "url": "https://omabrowser.org/oma/group/A0A8V0YFF9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96N23-1", "protein_name": "Cilia- and flagella-associated protein 54", "gene_name": "CFAP54", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAQGSPSSSPSDDSTTSGSLPELPPTSTATSRSPPESKGSSRSSLLQWTCPEDSLPLAVFYGPLDAKNPLLASCEKEIQELLGFMRKKKALATTEEEKHEFRRRCATSLFNIWTKYAPRLPADYYNEKLLKVGDSLCQMKEYKLALLQCYGRYLQQFNTNFDENKVDVTQFKATFFPKGFKDKTAGLTFHALSGKNMCNYQLVCDSDENLKNKESVVQCLHILSSLRLIMQVALPQEHLCWIIFNGTIYIYTICRKLMVIGQSSKALEYLLWASMCMESLVPLLSLRYLTWRATLYTAVCQCCYDCHAGIHGEAFARRALAKIDELRQLELMSSSKSQEESRRYFREATMKMAVMIFKRGVFESRRKNKAVFRPKIRINLREVQTLSWPRTVTERLLDEMFDSTASQFLAVLEALSDSNRRILQTGPIVTDEVEIHDVVSELFMAGKELLIMSNIGADGMLDFPKTSLLELMIGRKDVISVDAAVKFIKLAFTYEEWSLFESSAVHLIYFLQRQDDPESKKAEKDLTLLIAMEPLINVKRNKGLIFPLENYKEGQSTQIYLKKIAVHDTCLKTCGYSEDIFHLAATLYVCVCTAPQDVQPDKEIVVDTIMFLWQKCKLGIQRLNISRNDYAKFTQKISTNKWIYLLWQINEVIHCYKMEDIDIVVVAEVTLRLSEILESLGSPGRKFKQSLDVPLREGTNKFPGAPKGITEILPILQKNPVEQLLFAYKLLDRAIGGINLNCMLTSLPNGSSVIDHCYAKRTHHIDGDTYKPLASNSFMMDLHLELIQAQHRIAVVLLDKLQVLQTPTVSKDISTKGPEKLKQSGSTDCFTELNIMNKIKKNTLSKAIYLMQKALLIFEKDATSTSSWELLMEAYSLIQRIEAEQNALYSYQKYLESSKRKKSRVPPPPILLSRTHCSVTLKPAPFTSEVKVSWYCILGCKAEGSYGKVRLNNNHLPNSGEAIPADGKSVFEVKGLETNEKYVFAVAAYSNNGKLVGGAIGETTKPILVYPPLSTITARMFLTQVAYQVGNYELAKKVFSPVWDYFVASPLQDEQSVICLSNIITITQRRLHSDILAETSSILLYLFLRNIFVTSDIKIKEENLFCDNIKGNEIFPSQQIARLIECERVLVALELSNFLNDSSYALQAVTQCYGLLAPIIYHNIVLVPVVQILIKCIVVLQGLPSIVCSKKHTASFESIQHMIACCIFYITKILRSWREYDLAVMIINYGKKMLDITPGCKSLFDGSNEQEEMPEEDSSKKSLKTKKPQQILLPEKINEQLALLETHLLKLTKQYVTSELSGGEDPIFLYPVVLNWSVKGAVKEVMKFKQKPRFLEFFTQVMLKCMNEEKFHLMVEVTTPVHDFLKRRNESLLGLIKVKYKDSALNKKANKSLKFKAAVMEIGRSAEMQQRIRSKKKETLRDFIFKNPAISEMVAHERNRRTSVRKAAQRYLMDYLNPLILSYVKRKRFHRLSLEEMPWRAQMNLYLAGAHFNLVLQKLWECTKMKFGTSHMMVSFRSCDPNMFSLYNSGTVLPTRKLTVENYKAMLDFLLTAKKRKANLPSDAEEFSTFINSIMSDENMSKTQTVYDSDSQSGSSAKEKDRGANLCVMDHFMKIFLYCRRAMVLAHRGGYWTLLQNCCRALWNFTQELQILLKQAVDLDKTFPISQDGFLCTSVLPFYLGAELLIDMLIQLQNTSSIKPIEDKGEFSVPSCYGNIKNDNGGSSLTFEHPLDDVNVVDLKWIHDFVLKSLEVLYQVEKWETLVSLAIQFNTVSHERYTEQVTPLLVYAQRQLLLRIQKFKGPDITQQPCARYEAEYGEKITCRNFIGKQLKINSSTIEATSNCTDLLKMLISSEYSRAKALVCVPVDVTDTLRCFRETLEKSKYHNRSIRHSRKLLSLFLAQTQDVLQASNQRSLKVQALHSLGSLLIFAEKKRAAFKCWCQALDDIFRKPDVLHTWKEFGPSLTNVTNSHSPPGFKDYSEEFLSRVGIWGCLQGAVISAKIAQFIKSLNVEKKTDCCILSALLFQGLLRTTLPHPKAERCYAQYEITQLLPGIELFSDRYRADICSVIASLYYIIRELHFVRQNLIVLPLLALYQYFVSGICQDITRNLEARILKIEVLIDLRFFSEAFYEISQIFYGKNMPCPIPAGYKATGKMKIFQSFDSGKLLTSKENIQAIDELRNKGLPAVLVTIGQPHLLNKFNFVKAYFFLSVAATINCVPENKFKTVITNKSKPNLPNLEEIYSKDDGSSFYNLTKLKDEITLSMLKSMLLMEAEDRLNFLLSEVEQKTLSQCSAGELEIVVEARLQLAAVALQRHRAAYSAAIVFSTLTLLQDSKLFEKKVVQDDTENPVSPGTSVTENKDDSEFLDPISLNAREYFNIHLWLRCRLALVTAFVAQIHGIGIVKEDDMTDCLSLINEVCMEAKSAGDTELQAEFLTQAVILGLQEKHLKADIMTNLQDIIHLLEGNEFISPQSRLTLARSLVLLDDLTKAEKFKESPSSKTGKLNLLTRAHSILTEQMLAFGETIEFRSSNTKYANPLQPLKNIYLPHVMLLAKIKMRIGHTVAKQVYYKNKRKDPSKWLPALHLFDVALKLCRTTAVEEHEVEAEILFQKGKIERQILMEEKSPSFQLESLYEAIQLSLKNDQNSGLIRDSYLEMALLYFHLKKPKIKISGSPLTLKPPLRRSSSVKETSANKFEMYSSLAWIAIRAAAQVSEAVLAINLLIGKKNTRMHKVNQVALPNIPEFAALDLLSSYTDYLLDNYQVLFQTSCTFLYQNDDVCDSADGRKKTQTKVDITWILLLRYYIHLQRINNLSKLLASATPVSGISLPDDTLLTSLYNSELILRQKEVHFFLKKFLQLYSSSCIDEFPKELLCQLENPPLSEKDLRESSAKLYRDSSVQSILSFKPVSGSSCVDITPIEMVTQASNKELCFQWYIPPLDRPPKETEPMVLLLYAYNLKPLKISDVRHSTYNSTCVGSLWIPLNRVIAIHEKLSNLAQIAELSLPAAPEITSNENIYEVEVEEESVDNEMEDMIIQCCSEIASLFLNDKEPTPLSEVPFDISLPSIFNLERLFDLANGCILSGGSLFNWIVSIIP", "length": 3096 }, "evidence": [ { "id": "A0A8V0YFF9", "url": "https://omabrowser.org/oma/group/A0A8V0YFF9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "cilium assembly", "id": "GO:0060271", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060271", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFF9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFF9" } ], "pmid": "" }, { "name": "sperm flagellum assembly", "id": "GO:0120316", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120316", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFF9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFF9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1015, "end_pos": 1017, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1066, "end_pos": 1068, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1226, "end_pos": 1228, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1243, "end_pos": 1245, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1293, "end_pos": 1295, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1506, "end_pos": 1508, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1620, "end_pos": 1622, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1630, "end_pos": 1632, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1784, "end_pos": 1786, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1923, "end_pos": 1925, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2010, "end_pos": 2012, "annotation": "n_glycosylation_sequon" }, { "start_pos": 205, "end_pos": 207, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2129, "end_pos": 2131, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2226, "end_pos": 2228, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2723, "end_pos": 2725, "annotation": "n_glycosylation_sequon" }, { "start_pos": 291, "end_pos": 293, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2988, "end_pos": 2990, "annotation": "n_glycosylation_sequon" }, { "start_pos": 432, "end_pos": 434, "annotation": "n_glycosylation_sequon" }, { "start_pos": 519, "end_pos": 521, "annotation": "n_glycosylation_sequon" }, { "start_pos": 702, "end_pos": 704, "annotation": "n_glycosylation_sequon" }, { "start_pos": 730, "end_pos": 732, "annotation": "n_glycosylation_sequon" }, { "start_pos": 997, "end_pos": 999, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { 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"end_pos": 999 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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} ] } } ], "crossref": [ { "id": "A0A8V0YFH7", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YFH7", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd22674", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22674", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000253", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000253", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008984", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008984", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050923", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050923", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YA84", "url": "https://www.orthodb.org/?gene=A0A8V0YA84", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YFH1", "url": "https://www.orthodb.org/?gene=A0A8V0YFH1", "database": "OrthoDB", 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"database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YIK4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIK4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YIK4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIK4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVAVAELDQSEALNSRESQCGHIPDFGLGSRVDLSRESSGCPEAIPFRGAFMVRKPPPGLHLDVVKGDKLIEKLIIDEKKYYLFGRNPDLCDFTIDHQSCSRVHAALVYHKHLKRVFLIDLNSTHGTFLGHIRLEAHKPQQIPIDSTVSFGASTRAYTLREKPQTLPSAVKGDEKMGGEDEELKGLLGLPEEETELDNLTEFNTAHNKRISTLTIEEGNLDIQRPKRKRKNSRVTFSDDDEIINPEDVDPSVGRFRNMVQTAVVPVKKKRLDNPGSLTTDDSATRRMQNFPYSGGLYGGLPPTHNEAGSQSHGVHGTALIGGLPMPYPNLAPDVDLTPVVPSTVNMNPAPNPAVFNPEAVNEPKKKKYAKEAWPGKKPTPSLLI", "length": 384, "header": "tr|A0A8V0YFH7-1|A0A8V0YFH7_CHICK Isoform 1 of Nuclear inhibitor of protein phosphatase 1 OS=Gallus gallus OX=9031 GN=PPP1R8 PE=1 SV=1 CANONICAL=A0A8V0YFH7-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YA84-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFH7/entry#A0A8V0YA84-1", "sequence": { "sequence": "MGQMQDGGERELGRRRRRPLALRVPQLKLIIDEKKYYLFGRNPDLCDFTIDHQSCSRVHAALVYHKHLKRVFLIDLNSTHGTFLGHIRLEAHKPQQIPIDSTVSFGASTRAYTLREKPQTLPSAVKGDEKMGGEDEELKGLLGLPEEETELDNLTEFNTAHNKRISTLTIEEGNLDIQRPKRKRKNSRVTFSDDDEIINPEDVDPSVGRFRNMVQTAVVPVKKKRLDNPGSLTTDDSATRRMQNFPYSGGLYGGLPPTHNEAGSQSHGVHGTALIGGLPMPYPNLAPDVDLTPVVPSTVNMNPAPNPAVFNPEAVNEPKKKKYAKEAWPGKKPTPSLLI", "length": 339, "header": "tr|A0A8V0YA84-1|A0A8V0YA84_CHICK Computationally mapped isoform of Protein phosphatase 1 regulatory subunit 8 OS=Gallus gallus OX=9031 GN=PPP1R8 PE=1 SV=1 CANONICAL=A0A8V0YFH7-1" }, "locus": { "chromosome": "23", "start_pos": 1815570, "end_pos": 1800355, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030417.1", "url": "https://www.ensembl.org/id/ENSGALT00010030417.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017639.1", "url": "https://www.ensembl.org/id/ENSGALP00010017639.1" } ] } }, { "isoform_ac": "A0A8V0YFH1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFH7/entry#A0A8V0YFH1-1", "sequence": { "sequence": "MAANANSAGGGGGLSLFEAGKPPPGLHLDVVKGDKLIEKLIIDEKKYYLFGRNPDLCDFTIDHQSCSRVHAALVYHKHLKRVFLIDLNSTHGTFLGHIRLEAHKPQQIPIDSTVSFGASTRAYTLREKPQTLPSAVKGDEKMGGEDEELKGLLGLPEEETELDNLTEFNTAHNKRISTLTIEEGNLDIQRPKRKRKNSRVTFSDDDEIINPEDVDPSVGRFRNMVQTAVVPVKKKRLDNPGSLTTDDSATRRMQNFPYSGGLYGGLPPTHNEAGSQSHGVHGTALIGGLPMPYPNLAPDVDLTPVVPSTVNMNPAPNPAVFNPEAVNEPKKKKYAKEAWPGKKPTPSLLI", "length": 350, "header": "tr|A0A8V0YFH1-1|A0A8V0YFH7_CHICK Computationally mapped isoform of Nuclear inhibitor of protein phosphatase 1 OS=Gallus gallus OX=9031 GN=PPP1R8 PE=1 SV=1 CANONICAL=A0A8V0YFH7-1" }, "locus": { "chromosome": "23", "start_pos": 1815570, "end_pos": 1800371, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030422.1", "url": "https://www.ensembl.org/id/ENSGALT00010030422.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017643.1", "url": "https://www.ensembl.org/id/ENSGALP00010017643.1" } ] } }, { "isoform_ac": "A0A8V0YFH7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFH7/entry#A0A8V0YFH7-1", "sequence": { "sequence": "MVAVAELDQSEALNSRESQCGHIPDFGLGSRVDLSRESSGCPEAIPFRGAFMVRKPPPGLHLDVVKGDKLIEKLIIDEKKYYLFGRNPDLCDFTIDHQSCSRVHAALVYHKHLKRVFLIDLNSTHGTFLGHIRLEAHKPQQIPIDSTVSFGASTRAYTLREKPQTLPSAVKGDEKMGGEDEELKGLLGLPEEETELDNLTEFNTAHNKRISTLTIEEGNLDIQRPKRKRKNSRVTFSDDDEIINPEDVDPSVGRFRNMVQTAVVPVKKKRLDNPGSLTTDDSATRRMQNFPYSGGLYGGLPPTHNEAGSQSHGVHGTALIGGLPMPYPNLAPDVDLTPVVPSTVNMNPAPNPAVFNPEAVNEPKKKKYAKEAWPGKKPTPSLLI", "length": 384, "header": "tr|A0A8V0YFH7-1|A0A8V0YFH7_CHICK Isoform 1 of Nuclear inhibitor of protein phosphatase 1 OS=Gallus gallus OX=9031 GN=PPP1R8 PE=1 SV=1 CANONICAL=A0A8V0YFH7-1" }, "locus": { "chromosome": "23", "start_pos": 1815570, "end_pos": 1802866, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030429.1", "url": "https://www.ensembl.org/id/ENSGALT00010030429.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017648.1", "url": "https://www.ensembl.org/id/ENSGALP00010017648.1" } ] } }, { "isoform_ac": "A0A8V0YGI3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFH7/entry#A0A8V0YGI3-1", "sequence": { "sequence": "AELLGEFGGGGLAGKPPPGLHLDVVKGDKLIEKLIIDEKKYYLFGRNPDLCDFTIDHQSCSRVHAALVYHKHLKRVFLIDLNSTHGTFLGHIRLEAHKPQQIPIDSTVSFGASTRAYTLREKPQTLPSAVKGDEKMGGEDEELKGLLGLPEEETELDNLTEFNTAHNKRISTLTIEEGNLDIQRPKRKRKNSRVTFSDDDEIINPEDVDPSVGRFRNMVQTAVVPVKKKRLDNPGSLTTDDSATRRMQNFPYSGGLYGGLPPTHNEAGSQSHGVHGTALIGGLPMPYPNLAPDVDLTPVVPSTVNMNPAPNPAVFNPEAVNEPKKKKYAKEAC", "length": 333, "header": "tr|A0A8V0YGI3-1|A0A8V0YGI3_CHICK Computationally mapped isoform of Nuclear inhibitor of protein phosphatase 1 OS=Gallus gallus OX=9031 GN=PPP1R8 PE=1 SV=1 CANONICAL=A0A8V0YFH7-1" }, "locus": { "chromosome": "23", "start_pos": 1815575, "end_pos": 1807838, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030402.1", "url": "https://www.ensembl.org/id/ENSGALT00010030402.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017631.1", "url": "https://www.ensembl.org/id/ENSGALP00010017631.1" } ] } }, { "isoform_ac": "A0A8V0YIK4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFH7/entry#A0A8V0YIK4-1", "sequence": { "sequence": "MAANANSAGGGGGLSLFECPSWAGKPPPGLHLDVVKGDKLIEKLIIDEKKYYLFGRNPDLCDFTIDHQSCSRVHAALVYHKHLKRVFLIDLNSTHGTFLGHIRLEAHKPQQIPIDSTVSFGASTRAYTLREKPQTLPSAVKGDEKMGGEDEELKGLLGLPEEETELDNLTEFNTAHNKRISTLTIEEGNLDIQRPKRKRKNSRVTFSDDDEIINPGSLTTDDSATRRMQNFPYSGGLYGGLPPTHNEAGSQSHGVHGTALIGGLPMPYPNLAPDVDLTPVVPSTVNMNPAPNPAVFNPEAVNEPKKKKYAKEAWPGKKPTPSLLI", "length": 325, "header": "tr|A0A8V0YIK4-1|A0A8V0YIK4_CHICK Computationally mapped isoform of Nuclear inhibitor of protein phosphatase 1 OS=Gallus gallus OX=9031 GN=PPP1R8 PE=1 SV=1 CANONICAL=A0A8V0YFH7-1" }, "locus": { "chromosome": "23", "start_pos": 1815570, "end_pos": 1800371, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030414.1", "url": "https://www.ensembl.org/id/ENSGALT00010030414.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017637.1", "url": "https://www.ensembl.org/id/ENSGALP00010017637.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 379, "start_aa": "Thr", "end_pos": 379, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr379", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "R-GGA-9770562", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9770562", "resource": "Reactome", "description": "mRNA Polyadenylation" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFH7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFH7" } ], "pmid": "" }, { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFH7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFH7" } ], "pmid": "" }, { "name": "protein serine/threonine phosphatase inhibitor activity", "id": "GO:0004865", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004865", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFH7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFH7" } ], "pmid": "" }, { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFH7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFH7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFH7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFH7" } ], "pmid": "" }, { "name": "mRNA processing", "id": "GO:0006397", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006397", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFH7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFH7" } ], "pmid": "" }, { "name": "RNA splicing", "id": "GO:0008380", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008380", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFH7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFH7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nuclear speck", "id": "GO:0016607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016607", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFH7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFH7" } ], "pmid": "" }, { "name": "spliceosomal complex", "id": "GO:0005681", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005681", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFH7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFH7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 122, "end_pos": 124, "annotation": "n_glycosylation_sequon" }, { "start_pos": 198, "end_pos": 200, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YFH7", "database": "UniProtKB", "url": 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"glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YFN4-1", "uniprot_ac": "A0A8V0YFN4", "uniprot_id": "A0A8V0YFN4_CHICK", "mass": { "chemical_mass": 210711.0, "monoisotopic_mass": 210711.0 }, "refseq": {}, "gene_names": [ { "name": "TANC1", "type": "recommended", "evidence": [ { "id": "A0A8V0YFN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFN4" } ] } ], "protein_names": [ { "name": "Tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1", "type": "synonym", "evidence": [ { "id": "A0A8V0YFN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFN4/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFN4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFN4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TANC1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFN4", "locus": { "chromosome": "7", "start_pos": 36143094, "end_pos": 36055518, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010010917", "url": "https://www.ensembl.org/id/ENSGALG00010010917" } ] } } ], "crossref": [ { "id": "424330", "url": "https://www.ncbi.nlm.nih.gov/gene/424330", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011990", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011990", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019734", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019734", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036770", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036770", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050889", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050889", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR058018", "url": "https://www.ebi.ac.uk/interpro/entry/IPR058018", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR058056", "url": "https://www.ebi.ac.uk/interpro/entry/IPR058056", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "QGPDARM", "url": "https://omabrowser.org/oma/group/QGPDARM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y2D8", "url": "https://www.orthodb.org/?gene=A0A8V0Y2D8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y2G0", "url": "https://www.orthodb.org/?gene=A0A8V0Y2G0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y8S3", "url": "https://www.orthodb.org/?gene=A0A8V0Y8S3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YAU8", "url": "https://www.orthodb.org/?gene=A0A8V0YAU8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YAV3", "url": "https://www.orthodb.org/?gene=A0A8V0YAV3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YFH8", "url": "https://www.orthodb.org/?gene=A0A8V0YFH8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YFI2", "url": "https://www.orthodb.org/?gene=A0A8V0YFI2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YFL0", "url": "https://www.orthodb.org/?gene=A0A8V0YFL0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YFM4", "url": "https://www.orthodb.org/?gene=A0A8V0YFM4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YFN4", "url": "https://www.orthodb.org/?gene=A0A8V0YFN4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24166", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24166", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24166:SF23", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24166:SF23", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00023", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00023", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12796", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12796", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13637", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13637", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25520", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25520", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25521", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25521", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0Y2D8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2D8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y2D8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2D8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y2G0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2G0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y2G0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2G0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y8S3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y8S3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y8S3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y8S3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YAU8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAU8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YAU8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAU8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YAV3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAV3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YAV3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAV3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YFH8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFH8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YFH8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFH8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YFI2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFI2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YFI2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFI2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YFL0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFL0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YFL0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFL0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YFM4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFM4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YFM4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFM4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YFN4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFN4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YFN4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFN4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MARKTWVVPLPPAGGRAPSVKAAGVRVSKKQEAVPAGTNTRPTGRDKASIVSISKIHHMDVMLRKCHRTWQQHTPLSSCGGNIDVQSQTEGATLKMLKAVLKKSREGGKGSKKESAGDSCPENALQSVAASGHGADLPTGNQHIPGDAYRMNLAKGVSMSLPSSPLLPRQSYLMQSRSNKKSPGPIRKAKYVESPRVPGEAILLLRKQSGQEEPIQNAKPDKDSSCSPAAQELMTRLGFLLGEGIPTSAHIEEKNESMCTIASQGVSPCSTLTSSTTSPSTDSPCSTLNSCTGKAAANKGSPCETMRSPSSTLESKDSGIIATVTSSSENDDRSGSSLEWSKDGSLRAGAHRGIGHDRRTDNCSPVAEEEAVGSAENLPKEVPTGEGPVPYTQSSGSLIMPRPNSVAATSSTKLEDLSYLDGQRNAPLRTSIRLPWHNTAGGRVQQENKARFVTYKPQDILLKPLLFEVPSITTDSVFVGREWLFQAIEEKLKNTDLAESKGTVITGNVGFGKTAIISRLVALSCHGSRMRQIASNSPNSSPQSSDSCQEIPLSQLPLSTAPPSGTYTVKTMNCPGTPDNQNQTGDSVKRLASRVVAYHYCQADNTYTCLVPEFVHSIAALLCRSSQLTAYKDLLIKEPHLQSMLSLRSCVQDPAAAFKRGVLEPLSNLRKEQKIPEEEYIILIDGLNDAEFHKPDYGDTISSFLAKIICKFPPWLKLIVTVRTNFQEVARSLPFISISLDDFPDNKEIHNDLSAYIQYRINNSQEIINNISLNGKADAAIIGKVSNHLIMRSLGSYLYLKLTLDLFQKGHLVIKSASYKVVPVSLSELYLLQCNMKFMTNSAFERALPILNVALASLHPMTDEQIFQAINAGQINGEQQWEDFSQRMEALSCFLIKRRDKTRMFCHPSFREWLVWRADGENTDFLCEPRNGHALLAFMFSRQEGKLNRQQTMELGHHILKAHIFKGLSKRTGISSSHLQALWIGYSADGLSAALASLRNIYTPNVKVSRLLILAGANVNYKTEVLNNAPVLCVQSHLGHEEVVTLLLEYGAAIDGTSENGMTPLCYAAAAGHMNIVSLLCKKGAKADYLDKKGQCALVHSALRGHCDILEYLLNVAWAASSQEQNSLRKSQALQQSLTAASSMGHCQVVCYILAIEKEHEVDINVTDALWGETALTAAAGRGKLEVCELLLERGAAVSRANRRGVPPLFCAVRQGHWQIAKLLLEHGSDVNLSDKQGRTPLMVAACEGHLSTVEFLLSAGATISSLDKEGLTALGWACLKGHREVVQYLVEKGATVDQTDKNGRTPLDLAAFYGDADIVQYLVEKGAMIEHVDHSGMRPLDRAIGCRNTSVVVMLLRKGAKLGNAAWAMATSKPDILLILLQKLMEEGNILYKKGKMKEAAQRYQYALRKFPREGFGEEMKAFNEMRVSLYLNLSRCRRKTNDFGLAEEFATKALDLKPKSYEAYYARARAKRNSRKLLAALADLHEATKLCPGNQEIKRLLARVEEECKQFQRTQQQKHQCSQSGQQITNSDNEEEDVIQGVNENFHLQEKEEELPHPDESVSSPQRLQHSLATSSYTRNLQDSVQQKVRPVSPQGRTGNKYLREPGLIMQPTKQAQIVKTNQHLSSIQPGSKLGSSQCNTKTQSPFQHLSQSPVPVRHTKIQHLEGTSALSAGSVSTGASSELYNEKFTSSQCSHSQHSFAKKSKTTDPSPAPFQMNFSEARQQSPVPSTVSSTSPPSSMILASSTSSLTSVSSSADSIKGLGPDVRSKENKVNQVHGTAAEHRPRNTPFMGIMDKTARFQQQNQSSRSWHSQASDGLSTNVSSGSIQSSNFEQFSVKHSQTKTSSTVTIPGESNQNGMQAKVHEELRCQTAAYCQDNRAPKQVLHLYPDAPSKQHSHISKEGHLSHVTSTKPKRSFIESNV", "length": 1925, "header": "tr|A0A8V0YFN4-1|A0A8V0YFN4_CHICK Isoform 1 of Tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 OS=Gallus gallus OX=9031 GN=TANC1 PE=1 SV=1 CANONICAL=A0A8V0YFN4-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Y2D8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFN4/entry#A0A8V0Y2D8-1", "sequence": { "sequence": "MNLAKGVSMSLPSSPLLPRQSYLMQSRSNKKSPGPIRKAKYVESPRVPGEAILLLRKQSGQEEPIQNAKPDKDSSCSPAAQELMTRLGFLLGEGIPTSAHIEEKNESMCTIASQGVSPCSTLTSSTTSPSTDSPCSTLNSCTGKAAANKGSPCETMRSPSSTLESKDSGIIATVTSSSENDDRSGSSLEWSKDGSLRAGAHRGIGHDRRTDNCSPVAEEEAVGSAENLPKEVPTGEGPVPYTQSSGSLIMPRPNSVAATSSTKLEDLSYLDGQRNAPLRTSIRLPWHNTAGGRVQQENKARFVTYKPQDILLKPLLFEVPSITTDSVFVGREWLFQAIEEKLKNTDLAESKGTVITGNVGFGKTAIISRLVALSCHGSRMRQIASNSPNSSPQSSDSCQEIPLSQLPLSTAPPSGTYTVKTMNCPGTPDNQNQTGDSVKRLASRVVAYHYCQADNTYTCLVPEFVHSIAALLCRSSQLTAYKDLLIKEPHLQSMLSLRSCVQDPAAAFKRGVLEPLSNLRKEQKIPEEEYIILIDGLNDAEFHKPDYGDTISSFLAKIICKFPPWLKLIVTVRTNFQEVARSLPFISISLDDFPDNKEIHNDLSAYIQYRINNSQEIINNISLNGKADAAIIGKVSNHLIMRSLGSYLYLKLTLDLFQKGHLVIKSASYKVVPVSLSELYLLQCNMKFMTNSAFERALPILNVALASLHPMTDEQIFQAINAGQINGEQQWEDFSQRMEALSCFLIKRRDKTRMFCHPSFREWLVWRADGENTDFLCEPRNGHALLAFMFSRQEGKLNRQQTMELGHHILKAHIFKGLSKRTGISSSHLQALWIGYSADGLSAALASLRNIYTPNVKVSRLLILAGANVNYKTEVLNNAPVLCVQSHLGHEEVVTLLLEYGAAIDGTSENGMTPLCYAAAAGHMNIVSLLCKKGAKADYLDKKGQCALVHSALRGHCDILEYLLNVAWAASSQEQNSLRKSQALQQSLTAASSMGHCQVVCYILAIEKEHEVDINVTDALWGETALTAAAGRGKLEVCELLLERGAAVSRANRRGVPPLFCAVRQGHWQIAKLLLEHGSDVNLSDKQGRTPLMVAACEGHLSTVEFLLSAGATISSLDKEGLTALGWACLKGHREVVQYLVEKGATVDQTDKNGRTPLDLAAFYGDADIVQYLVEKGAMIEHVDHSGMRPLDRAIGCRNTSVVVMLLRKGAKLGNAAWAMATSKPDILLILLQKLMEEGNILYKKGKMKEAAQRYQYALRKFPREGFGEEMKAFNEMRVSLYLNLSRCRRKTNDFGLAEEFATKALDLKPKSYEAYYARARAKRNSRKLLAALADLHEATKLCPGNQEIKRLLARVEEECKQFQRTQQQKHQCSQSGQQITNSDNEEEDVIQGVNENFHLQEKEEELPHPDESVSSPQRLQHSLATSSYTRNLQDSVQQKVRPVSPQGRTGNKYLREPGLIMQPTKQAQIVKTNQHLSSIQPGSKLGSSQCNTKTQSPFQHLSQSPVPVRHTKIQHLEGTSALSAGSVSTGASSELYNEKFTSSQCSHSQHSFAKKSKTTDPSPAPFQMNFSEARQQSPVPSTVSSTSPPSSMILASSTSSLTSVSSSADSIKGLGPDVRSKENKVNQVHGTAAEHRPRNTPFMGIMDKTARFQQQNQSSRSWHSQASDGLSTNVSSGSIQSSNFEQFSVKHSQTKTSSTVTIPGESNQNGMQAKVHEELRCQTAAYCQDNRAPKQVLHLYPDAPSKQHSHISKEGHLSHVTSTKPKRSFIESNV", "length": 1775, "header": "tr|A0A8V0Y2D8-1|A0A8V0Y2D8_CHICK Computationally mapped isoform of Tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 OS=Gallus gallus OX=9031 GN=TANC1 PE=1 SV=1 CANONICAL=A0A8V0YFN4-1" }, "locus": { "chromosome": "7", "start_pos": 36142090, "end_pos": 36102348, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026144.1", "url": "https://www.ensembl.org/id/ENSGALT00010026144.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010014771.1", "url": "https://www.ensembl.org/id/ENSGALP00010014771.1" } ] } }, { "isoform_ac": "A0A8V0Y2G0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFN4/entry#A0A8V0Y2G0-1", "sequence": { "sequence": "MKGATLKMLKAVLKKSREGGKGSKKESAGDSCPENALQSVAASGHGADLPTGNQHIPGDAYRMNLAKGVSMSLPSSPLLPRQSYLMQSRSNKKSPGPIRKAKYVESPRVPGEAILLLRKQSGQEEPIQNAKPDKDSSCSPAAQELMTRLGFLLGEGIPTSAHIEEKNESMCTIASQGVSPCSTLTSSTTSPSTDSPCSTLNSCTGKAAANKGSPCETMRSPSSTLESKDSGIIATVTSSSENDDRSGSSLEWSKDGSLRAGAHRGIGHDRRTDNCSPVAEEEAVGSAENLPKEVPTGEGPVPYTQSSGSLIMPRPNSVAATSSTKLEDLSYLDGQRNAPLRTSIRLPWHNTAGGRVQQENKARFVTYKPQDILLKPLLFEVPSITTDSVFVGREWLFQAIEEKLKNTDLAESKGTVITGNVGFGKTAIISRLVALSCHGSRMRQIASNSPNSSPQSSDSCQEIPLSQLPLSTAPPSGTYTVKTMNCPGTPDNQNQTGDSVKRLASRVVAYHYCQADNTYTCLVPEFVHSIAALLCRSSQLTAYKDLLIKEPHLQSMLSLRSCVQDPAAAFKRGVLEPLSNLRKEQKIPEEEYIILIDGLNDAEFHKPDYGDTISSFLAKIICKFPPWLKLIVTVRTNFQEVARSLPFISISLDDFPDNKEIHNDLSAYIQYRINNSQEIINNISLNGKADAAIIGKVSNHLIMRSLGSYLYLKLTLDLFQKGHLVIKSASYKVVPVSLSELYLLQCNMKFMTNSAFERALPILNVALASLHPMTDEQIFQAINAGQINGEQQWEDFSQRMEALSCFLIKRRDKTRMFCHPSFREWLVWRADGENTDFLCEPRNGHALLAFMFSRQEGKLNRQQTMELGHHILKAHIFKGLSKRTGISSSHLQALWIGYSADGLSAALASLRNIYTPNVKVSRLLILAGANVNYKTEVLNNAPVLCVQSHLGHEEVVTLLLEYGAAIDGTSENGMTPLCYAAAAGHMNIVSLLCKKGAKADYLDKKGQCALVHSALRGHCDILEYLLNVAWAASSQEQNSLRKSQALQQSLTAASSMGHCQVVCYILAIEKEHEVDINVTDALWGETALTAAAGRGKLEVCELLLERGAAVSRANRRGVPPLFCAVRQGHWQIAKLLLEHGSDVNLSDKQGRTPLMVAACEGHLSTVEFLLSAGATISSLDKEGLTALGWACLKGHREVVQYLVEKGATVDQTDKNGRTPLDLAAFYGDADIVQYLVEKGAMIEHVDHSGMRPLDRAIGCRNTSVVVMLLRKGAKLGNAAWAMATSKPDILLILLQKLMEEGNILYKKGKMKEAAQRYQYALRKFPREGFGEEMKAFNEMRVSLYLNLSRCRRKTNDFGLAEEFATKALDLKPKSYEAYYARARAKRNSRKLLAALADLHEATKLCPGNQEIKRLLARVEEECKQFQRTQQQKHQCSQSGQQITNSDNEEEDVIQGVNENFHLQEKEEELPHPDESVSSPQRLQHSLATSSYTRNLQDSVQQKVRPVSPQGRTGNKYLREPGLIMQPTKQAQIVKTNQHLSSIQPGSKLGSSQCNTKTQSPFQHLSQSPVPVRHTKIQHLEGTSALSAGSVSTGASSELYNEKFTSSQCSHSQHSFAKKSKTTDPSPAPFQMNFSEARQQSPVPSTVSSTSPPSSMILASSTSSLTSVSSSADSIKGLGPDVRSKENKVNQVHGTAAEHRPRNTPFMGIMDKTARFQQQNQSSRSWHSQASDGLSTNVSSGSIQSSNFEQFSVKHSQTKTSSTVTIPGESNQNGMQAKVHEELRCQTAAYCQDNRAPKQVLHLYPDAPSKQHSHISKEGHLSHVTSTKPKRSFIESNV", "length": 1837, "header": "tr|A0A8V0Y2G0-1|A0A8V0Y2G0_CHICK Computationally mapped isoform of Tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 OS=Gallus gallus OX=9031 GN=TANC1 PE=1 SV=1 CANONICAL=A0A8V0YFN4-1" }, "locus": { "chromosome": "7", "start_pos": 36142090, "end_pos": 36062234, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026172.1", "url": "https://www.ensembl.org/id/ENSGALT00010026172.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010014796.1", "url": "https://www.ensembl.org/id/ENSGALP00010014796.1" } ] } }, { "isoform_ac": "A0A8V0Y8S3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFN4/entry#A0A8V0Y8S3-1", "sequence": { "sequence": "MLKAVLKKSREGGKGSKKESGDSCPENALQSVAASGHGADLPTGNQHIPGDAYRMNLAKGVSMSLPSSPLLPRQSYLMQSRSNKKSPGPIRKAKYVESPRVPGEAILLLRKQSGQEEPIQNAKPDKDSSCSPAAQELMTRLGFLLGEGIPTSAHIEEKNESMCTIASQGVSPCSTLTSSTTSPSTDSPCSTLNSCTGKAAANKGSPCETMRSPSSTLESKDSGIIATVTSSSENDDRSGSSLEWSKDGSLRAGAHRGIGHDRRTDNCSPVAEEEAVGSAENLPKEVPTGEGPVPYTQSSGSLIMPRPNSVAATSSTKLEDLSYLDGQRNAPLRTSIRLPWHNTAGGRVQQENKARFVTYKPQDILLKPLLFEVPSITTDSVFVGREWLFQAIEEKLKNTDLAESKGTVITGNVGFGKTAIISRLVALSCHGSRMRQIASNSPNSSPQSSDSCQEIPLSQLPLSTAPPSGTYTVKTMNCPGTPDNQNQTGDSVKRLASRVVAYHYCQADNTYTCLVPEFVHSIAALLCRSSQLTAYKDLLIKEPHLQSMLSLRSCVQDPAAAFKRGVLEPLSNLRKEQKIPEEEYIILIDGLNDAEFHKPDYGDTISSFLAKIICKFPPWLKLIVTVRTNFQEVARSLPFISISLDDFPDNKEIHNDLSAYIQYRINNSQEIINNISLNGKADAAIIGKVSNHLIMRSLGSYLYLKLTLDLFQKGHLVIKSASYKVVPVSLSELYLLQCNMKFMTNSAFERALPILNVALASLHPMTDEQIFQAINAGQINGEQQWEDFSQRMEALSCFLIKRRDKTRMFCHPSFREWLVWRADGENTDFLCEPRNGHALLAFMFSRQEGKLNRQQTMELGHHILKAHIFKGLSKRTGISSSHLQALWIGYSADGLSAALASLRNIYTPNVKVSRLLILAGANVNYKTEVLNNAPVLCVQSHLGHEEVVTLLLEYGAAIDGTSENGMTPLCYAAAAGHMNIVSLLCKKGAKADYLDKKGQCALVHSALRGHCDILEYLLNVAWAASSQEQNSLRKSQALQQSLTAASSMGHCQVVCYILAIEKEHEVDINVTDALWGETALTAAAGRGKLEVCELLLERGAAVSRANRRGVPPLFCAVRQGHWQIAKLLLEHGSDVNLSDKQGRTPLMVAACEGHLSTVEFLLSAGATISSLDKEGLTALGWACLKGHREVVQYLVEKGATVDQTDKNGRTPLDLAAFYGDADIVQYLVEKGAMIEHVDHSGMRPLDRAIGCRNTSVVVMLLRKGAKLGNAAWAMATSKPDILLILLQKLMEEGNILYKKGKMKEAAQRYQYALRKFPREGFGEEMKAFNEMRVSLYLNLSRCRRKTNDFGLAEEFATKALDLKPKSYEAYYARARAKRNSRKLLAALADLHEATKLCPGNQEIKRLLARVEEECKQFQRTQQQKHQCSQSGQQITNSDNEEEDVIQGVNENFHLQEKEEELPHPDESVSSPQRLQHSLATSSYTRNLQDSVQQKVRPVSPQGRTGNKYLREPGLIMQPTKQAQIVKTNQHLSSIQPGSKLGSSQCNTKTQSPFQHLSQSPVPVRHTKIQHLEGTSALSAGSVSTGASSELYNEKFTSSQCSHSQHSFAKKSKTTDPSPAPFQMNFSEARQQSPVPSTVSSTSPPSSMILASSTSSLTSVSSSADSIKGLGPDVRSKENKVNQVHGTAAEHRPRNTPFMGIMDKTARFQQQNQSSRSWHSQASDGLSTNVSSGSIQSSNFEQFSVKHSQTKTSSTVTIPGESNQNGMQAKVHEELRCQTAAYCQDNRAPKQVLHLYPDAPSKQHSHISKEGHLSHVTSTKPKRSFIESNV", "length": 1829, "header": "tr|A0A8V0Y8S3-1|A0A8V0Y8S3_CHICK Computationally mapped isoform of Tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 OS=Gallus gallus OX=9031 GN=TANC1 PE=1 SV=1 CANONICAL=A0A8V0YFN4-1" }, "locus": { "chromosome": "7", "start_pos": 36142090, "end_pos": 36094971, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026184.1", "url": "https://www.ensembl.org/id/ENSGALT00010026184.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010014808.1", "url": "https://www.ensembl.org/id/ENSGALP00010014808.1" } ] } }, { "isoform_ac": "A0A8V0YAU8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFN4/entry#A0A8V0YAU8-1", "sequence": { "sequence": "MTKPDKDSSCSPAAQELMTRLGFLLGEGIPTSAHIEEKNESMCTIASQGVSPCSTLTSSTTSPSTDSPCSTLNSCTGKAAANKGSPCETMRSPSSTLESKDSGIIATVTSSSENDDRSGSSLEWSKDGSLRAGAHRGIGHDRRTDNCSPVAEEEAVGSAENLPKEVPTGEGPVPYTQSSGSLIMPRPNSVAATSSTKLEDLSYLDGQRNAPLRTSIRLPWHNTAGGRVQQENKARFVTYKPQDILLKPLLFEVPSITTDSVFVGREWLFQAIEEKLKNTDLAESKGTVITGNVGFGKTAIISRLVALSCHGSRMRQIASNSPNSSPQSSDSCQEIPLSQLPLSTAPPSGTYTVKTMNCPGTPDNQNQTGDSVKRLASRVVAYHYCQADNTYTCLVPEFVHSIAALLCRSSQLTAYKDLLIKEPHLQSMLSLRSCVQDPAAAFKRGVLEPLSNLRKEQKIPEEEYIILIDGLNDAEFHKPDYGDTISSFLAKIICKFPPWLKLIVTVRTNFQEVARSLPFISISLDDFPDNKEIHNDLSAYIQYRINNSQEIINNISLNGKADAAIIGKVSNHLIMRSLGSYLYLKLTLDLFQKGHLVIKSASYKVVPVSLSELYLLQCNMKFMTNSAFERALPILNVALASLHPMTDEQIFQAINAGQINGEQQWEDFSQRMEALSCFLIKRRDKTRMFCHPSFREWLVWRADGENTDFLCEPRNGHALLAFMFSRQEGKLNRQQTMELGHHILKAHIFKGLSKRTGISSSHLQALWIGYSADGLSAALASLRNIYTPNVKVSRLLILAGANVNYKTEVLNNAPVLCVQSHLGHEEVVTLLLEYGAAIDGTSENGMTPLCYAAAAGHMNIVSLLCKKGAKADYLDKKGQCALVHSALRGHCDILEYLLNVAWAASSQEQNSLRKSQALQQSLTAASSMGHCQVVCYILAIEKEHEVDINVTDALWGETALTAAAGRGKLEVCELLLERGAAVSRANRRGVPPLFCAVRQGHWQIAKLLLEHGSDVNLSDKQGRTPLMVAACEGHLSTVEFLLSAGATISSLDKEGLTALGWACLKGHREVVQYLVEKGATVDQTDKNGRTPLDLAAFYGDADIVQYLVEKGAMIEHVDHSGMRPLDRAIGCRNTSVVVMLLRKGAKLGNAAWAMATSKPDILLILLQKLMEEGNILYKKGKMKEAAQRYQYALRKFPREGFGEEMKAFNEMRVSLYLNLSRCRRKTNDFGLAEEFATKALDLKPKSYEAYYARARAKRNSRKLLAALADLHEATKLCPGNQEIKRLLARVEEECKQFQRTQQQKHQCSQSGQQITNSDNEEEDVIQGVNENFHLQEKEEELPHPDESVSSPQRLQHSLATSSYTRNLQDSVQQKVRPVSPQGRTGNKYLREPGLIMQPTKQAQIVKTNQHLSSIQPGSKLGSSQCNTKTQSPFQHLSQSPVPVRHTKIQHLEGTSALSAGSVSTGASSELYNEKFTSSQCSHSQHSFAKKSKTTDPSPAPFQMNFSEARQQSPVPSTVSSTSPPSSMILASSTSSLTSVSSSADSIKGLGPDVRSKENKVNQVHGTAAEHRPRNTPFMGIMDKTARFQQQNQSSRSWHSQASDGLSTNVSSGSIQSSNFEQFSVKHSQTKTSSTVTIPGESNQNGMQAKVHEELRCQTAAYCQDNRAPKQVLHLYPDAPSKQHSHISKEGHLSHVTSTKPKRSFIESNV", "length": 1709, "header": "tr|A0A8V0YAU8-1|A0A8V0YAU8_CHICK Computationally mapped isoform of Tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 OS=Gallus gallus OX=9031 GN=TANC1 PE=1 SV=1 CANONICAL=A0A8V0YFN4-1" }, "locus": { "chromosome": "7", "start_pos": 36142090, "end_pos": 36111431, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026124.1", "url": "https://www.ensembl.org/id/ENSGALT00010026124.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010014748.1", "url": "https://www.ensembl.org/id/ENSGALP00010014748.1" } ] } }, { "isoform_ac": "A0A8V0YAV3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFN4/entry#A0A8V0YAV3-1", "sequence": { "sequence": "MQGLHCYSFGCHRTWQQHTPLSSCGGNIDVQSQTEGATLKMLKAVLKKSREGGKGSKKESAGDSCPENALQSVAASGHGADLPTGNQHIPGDAYRMNLAKGVSMSLPSSPLLPRQSYLMQSRSNKKSPGPIRKAKYVESPRVPGEAILLLRKQSGQEEPIQNAKPDKDSSCSPAAQELMTRLGFLLGEGIPTSAHIEEKNESMCTIASQGVSPCSTLTSSTTSPSTDSPCSTLNSCTGKAAANKGSPCETMRSPSSTLESKDSGIIATVTSSSENDDRSGSSLEWSKDGSLRAGAHRGIGHDRRTDNCSPVAEEEAVGSAENLPKEVPTGEGPVPYTQSSGSLIMPRPNSVAATSSTKLEDLSYLDGQRNAPLRTSIRLPWHNTAGGRVQQENKARFVTYKPQDILLKPLLFEVPSITTDSVFVGREWLFQAIEEKLKNTDLAESKGTVITGNVGFGKTAIISRLVALSCHGSRMRQIASNSPNSSPQSSDSCQEIPLSQLPLSTAPPSGTYTVKTMNCPGTPDNQNQTGDSVKRLASRVVAYHYCQADNTYTCLVPEFVHSIAALLCRSSQLTAYKDLLIKEPHLQSMLSLRSCVQDPAAAFKRGVLEPLSNLRKEQKIPEEEYIILIDGLNDAEFHKPDYGDTISSFLAKIICKFPPWLKLIVTVRTNFQEVARSLPFISISLDDFPDNKEIHNDLSAYIQYRINNSQEIINNISLNGKADAAIIGKVSNHLIMRSLGSYLYLKLTLDLFQKGHLVIKSASYKVVPVSLSELYLLQCNMKFMTNSAFERALPILNVALASLHPMTDEQIFQAINAGQINGEQQWEDFSQRMEALSCFLIKRRDKTRMFCHPSFREWLVWRADGENTDFLCEPRNGHALLAFMFSRQEGKLNRQQTMELGHHILKAHIFKGLSKRTGISSSHLQALWIGYSADGLSAALASLRNIYTPNVKVSRLLILAGANVNYKTEVLNNAPVLCVQSHLGHEEVVTLLLEYGAAIDGTSENGMTPLCYAAAAGHMNIVSLLCKKGAKADYLDKKGQCALVHSALRGHCDILEYLLNVAWAASSQEQNSLRKSQALQQSLTAASSMGHCQVVCYILAIEKEHEVDINVTDALWGETALTAAAGRGKLEVCELLLERGAAVSRANRRGVPPLFCAVRQGHWQIAKLLLEHGSDVNLSDKQGRTPLMVAACEGHLSTVEFLLSAGATISSLDKEGLTALGWACLKGHREVVQYLVEKGATVDQTDKNGRTPLDLAAFYGDADIVQYLVEKGAMIEHVDHSGMRPLDRAIGCRNTSVVVMLLRKGAKLGNAAWAMATSKPDILLILLQKLMEEGNILYKKGKMKEAAQRYQYALRKFPREGFGEEMKAFNEMRVSLYLNLSRCRRKTNDFGLAEEFATKALDLKPKSYEAYYARARAKRNSRKLLAALADLHEATKLCPGNQEIKRLLARVEEECKQFQRTQQQKHQCSQSGQQITNSDNEEEDVIQGVNENFHLQEKEEELPHPDESVSSPQRLQHSLATSSYTRNLQDSVQQKVRPVSPQGRTGNKYLREPGLIMQPTKQAQIVKTNQHLSSIQPGSKLGSSQCNTKTQSPFQHLSQSPVPVRHTKIQHLEGTSALSAGSVSTGASSELYNEKFTSSQCSHSQHSFAKKSKTTDPSPAPFQMNFSEARQQSPVPSTVSSTSPPSSMILASSTSSLTSVSSSADSIKGLGPDVRSKENKVNQVHGTAAEHRPRNTPFMGIMDKTARFQQQNQSSRSWHSQASDGLSTNVSSGSIQSSNFEQFSVKHSQTKTSSTVTIPGESNQNGMQAKVHEELRCQTAAYCQDNRAPKQVLHLYPDAPSKQHSHISKEGHLSHVTSTKPKRSFIESNV", "length": 1870, "header": "tr|A0A8V0YAV3-1|A0A8V0YAV3_CHICK Computationally mapped isoform of Tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 OS=Gallus gallus OX=9031 GN=TANC1 PE=1 SV=1 CANONICAL=A0A8V0YFN4-1" }, "locus": { "chromosome": "7", "start_pos": 36142090, "end_pos": 36089364, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026129.1", "url": "https://www.ensembl.org/id/ENSGALT00010026129.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010014753.1", "url": "https://www.ensembl.org/id/ENSGALP00010014753.1" } ] } }, { "isoform_ac": "A0A8V0YFH8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFN4/entry#A0A8V0YFH8-1", "sequence": { "sequence": "MGARGVQPGGGSEETLLCSVRCHRTWQQHTPLSSCGGNIDVQSQTEGATLKMLKAVLKKSREGGKGSKKESAGDSCPENALQSVAASGHGADLPTGNQHIPGDAYRMNLAKGVSMSLPSSPLLPRQSYLMQSRSNKKSPGPIRKAKYVESPRVPGEAILLLRKQSGQEEPIQNAKPDKDSSCSPAAQELMTRLGFLLGEGIPTSAHIEEKNESMCTIASQGVSPCSTLTSSTTSPSTDSPCSTLNSCTGKAAANKGSPCETMRSPSSTLESKDSGIIATVTSSSENDDRSGSSLEWSKDGSLRAGAHRGIGHDRRTDNCSPVAEEEAVGSAENLPKEVPTGEGPVPYTQSSGSLIMPRPNSVAATSSTKLEDLSYLDGQRNAPLRTSIRLPWHNTAGGRVQQENKARFVTYKPQDILLKPLLFEVPSITTDSVFVGREWLFQAIEEKLKNTDLAESKGTVITGNVGFGKTAIISRLVALSCHGSRMRQIASNSPNSSPQSSDSCQEIPLSQLPLSTAPPSGTYTVKTMNCPGTPDNQNQTGDSVKRLASRVVAYHYCQADNTYTCLVPEFVHSIAALLCRSSQLTAYKDLLIKEPHLQSMLSLRSCVQDPAAAFKRGVLEPLSNLRKEQKIPEEEYIILIDGLNDAEFHKPDYGDTISSFLAKIICKFPPWLKLIVTVRTNFQEVARSLPFISISLDDFPDNKEIHNDLSAYIQYRINNSQEIINNISLNGKADAAIIGKVSNHLIMRSLGSYLYLKLTLDLFQKGHLVIKSASYKVVPVSLSELYLLQCNMKFMTNSAFERALPILNVALASLHPMTDEQIFQAINAGQINGEQQWEDFSQRMEALSCFLIKRRDKTRMFCHPSFREWLVWRADGENTDFLCEPRNGHALLAFMFSRQEGKLNRQQTMELGHHILKAHIFKGLSKRTGISSSHLQALWIGYSADGLSAALASLRNIYTPNVKVSRLLILAGANVNYKTEVLNNAPVLCVQSHLGHEEVVTLLLEYGAAIDGTSENGMTPLCYAAAAGHMNIVSLLCKKGAKADYLDKKGQCALVHSALRGHCDILEYLLNVAWAASSQEQNSLRKSQALQQSLTAASSMGHCQVVCYILAIEKEHEVDINVTDALWGETALTAAAGRGKLEVCELLLERGAAVSRANRRGVPPLFCAVRQGHWQIAKLLLEHGSDVNLSDKQGRTPLMVAACEGHLSTVEFLLSAGATISSLDKEGLTALGWACLKGHREVVQYLVEKGATVDQTDKNGRTPLDLAAFYGDADIVQYLVEKGAMIEHVDHSGMRPLDRAIGCRNTSVVVMLLRKGAKLGNAAWAMATSKPDILLILLQKLMEEGNILYKKGKMKEAAQRYQYALRKFPREGFGEEMKAFNEMRVSLYLNLSRCRRKTNDFGLAEEFATKALDLKPKSYEAYYARARAKRNSRKLLAALADLHEATKLCPGNQEIKRLLARVEEECKQFQRTQQQKHQCSQSGQQITNSDNEEEDVIQGVNENFHLQEKEEELPHPDESVSSPQRLQHSLATSSYTRNLQDSVQQKVRPVSPQGRTGNKYLREPGLIMQPTKQAQIVKTNQHLSSIQPGSKLGSSQCNTKTQSPFQHLSQSPVPVRHTKIQHLEGTSALSAGSVSTGASSELYNEKFTSSQCSHSQHSFAKKSKTTDPSPAPFQMNFSEARQQSPVPSTVSSTSPPSSMILASSTSSLTSVSSSADSIKGLGPDVRSKENKVNQVHGTAAEHRPRNTPFMGIMDKTARFQQQNQSSRSWHSQASDGLSTNVSSGSIQSSNFEQFSVKHSQTKTSSTVTIPGESNQNGMQAKVHEELRCQTAAYCQDNRAPKQVLHLYPDAPSKQHSHISKEGHLSHVTSTKPKRSFIESNV", "length": 1881, "header": "tr|A0A8V0YFH8-1|A0A8V0YFN4_CHICK Computationally mapped isoform of Tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 OS=Gallus gallus OX=9031 GN=TANC1 PE=1 SV=1 CANONICAL=A0A8V0YFN4-1" }, "locus": { "chromosome": "7", "start_pos": 36142090, "end_pos": 36091655, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026127.1", "url": "https://www.ensembl.org/id/ENSGALT00010026127.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010014751.1", "url": "https://www.ensembl.org/id/ENSGALP00010014751.1" } ] } }, { "isoform_ac": "A0A8V0YFI2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFN4/entry#A0A8V0YFI2-1", "sequence": { "sequence": "MKCQKCAGWQGATLKMLKAVLKKSREGGKGSKKESAGDSCPENALQSVAASGHGADLPTGNQHIPGDAYRMNLAKGVSMSLPSSPLLPRQSYLMQSRSNKKSPGPIRKAKYVESPRVPGEAILLLRKQSGQEEPIQNAKPDKDSSCSPAAQELMTRLGFLLGEGIPTSAHIEEKNESMCTIASQGVSPCSTLTSSTTSPSTDSPCSTLNSCTGKAAANKGSPCETMRSPSSTLESKDSGIIATVTSSSENDDRSGSSLEWSKDGSLRAGAHRGIGHDRRTDNCSPVAEEEAVGSAENLPKEVPTGEGPVPYTQSSGSLIMPRPNSVAATSSTKLEDLSYLDGQRNAPLRTSIRLPWHNTAGGRVQQENKARFVTYKPQDILLKPLLFEVPSITTDSVFVGREWLFQAIEEKLKNTDLAESKGTVITGNVGFGKTAIISRLVALSCHGSRMRQIASNSPNSSPQSSDSCQEIPLSQLPLSTAPPSGTYTVKTMNCPGTPDNQNQTGDSVKRLASRVVAYHYCQADNTYTCLVPEFVHSIAALLCRSSQLTAYKDLLIKEPHLQSMLSLRSCVQDPAAAFKRGVLEPLSNLRKEQKIPEEEYIILIDGLNDAEFHKPDYGDTISSFLAKIICKFPPWLKLIVTVRTNFQEVARSLPFISISLDDFPDNKEIHNDLSAYIQYRINNSQEIINNISLNGKADAAIIGKVSNHLIMRSLGSYLYLKLTLDLFQKGHLVIKSASYKVVPVSLSELYLLQCNMKFMTNSAFERALPILNVALASLHPMTDEQIFQAINAGQINGEQQWEDFSQRMEALSCFLIKRRDKTRMFCHPSFREWLVWRADGENTDFLCEPRNGHALLAFMFSRQEGKLNRQQTMELGHHILKAHIFKGLSKRTGISSSHLQALWIGYSADGLSAALASLRNIYTPNVKVSRLLILAGANVNYKTEVLNNAPVLCVQSHLGHEEVVTLLLEYGAAIDGTSENGMTPLCYAAAAGHMNIVSLLCKKGAKADYLDKKGQCALVHSALRGHCDILEYLLNVAWAASSQEQNSLRKSQALQQSLTAASSMGHCQVVCYILAIEKEHEVDINVTDALWGETALTAAAGRGKLEVCELLLERGAAVSRANRRGVPPLFCAVRQGHWQIAKLLLEHGSDVNLSDKQGRTPLMVAACEGHLSTVEFLLSAGATISSLDKEGLTALGWACLKGHREVVQYLVEKGATVDQTDKNGRTPLDLAAFYGDADIVQYLVEKGAMIEHVDHSGMRPLDRAIGCRNTSVVVMLLRKGAKLGNAAWAMATSKPDILLILLQKLMEEGNILYKKGKMKEAAQRYQYALRKFPREGFGEEMKAFNEMRVSLYLNLSRCRRKTNDFGLAEEFATKALDLKPKSYEAYYARARAKRNSRKLLAALADLHEATKLCPGNQEIKRLLARVEEECKQFQRTQQQKHQCSQSGQQITNSDNEEEDVIQGVNENFHLQEKEEELPHPDESVSSPQRLQHSLATSSYTRNLQDSVQQKVRPVSPQGRTGNKYLREPGLIMQPTKQAQIVKTNQHLSSIQPGSKLGSSQCNTKTQSPFQHLSQSPVPVRHTKIQHLEGTSALSAGSVSTGASSELYNEKFTSSQCSHSQHSFAKKSKTTDPSPAPFQMNFSEARQQSPVPSTVSSTSPPSSMILASSTSSLTSVSSSADSIKGLGPDVRSKENKVNQVHGTAAEHRPRNTPFMGIMDKTARFQQQNQSSRSWHSQASDGLSTNVSSGSIQSSNFEQFSVKHSQTKTSSTVTIPGESNQNGMQAKVHEELRCQTAAYCQDNRAPKQVLHLYPDAPSKQHSHISKEGHLSHVTSTKPKRSFIESNV", "length": 1845, "header": "tr|A0A8V0YFI2-1|A0A8V0YFI2_CHICK Computationally mapped isoform of Tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 OS=Gallus gallus OX=9031 GN=TANC1 PE=1 SV=1 CANONICAL=A0A8V0YFN4-1" }, "locus": { "chromosome": "7", "start_pos": 36142090, "end_pos": 36078236, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026132.1", "url": "https://www.ensembl.org/id/ENSGALT00010026132.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010014756.1", "url": "https://www.ensembl.org/id/ENSGALP00010014756.1" } ] } }, { "isoform_ac": "A0A8V0YFL0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFN4/entry#A0A8V0YFL0-1", "sequence": { "sequence": "MLVPQVYNQCHRTWQQHTPLSSCGGNIDVQSQTEGATLKMLKAVLKKSREGGKGSKKESAGDSCPENALQSVAASGHGADLPTGNQHIPGDAYRMNLAKGVSMSLPSSPLLPRQSYLMQSRSNKKSPGPIRKAKYVESPRVPGEAILLLRKQSGQEEPIQNAKPDKDSSCSPAAQELMTRLGFLLGEGIPTSAHIEEKNESMCTIASQGVSPCSTLTSSTTSPSTDSPCSTLNSCTGKAAANKGSPCETMRSPSSTLESKDSGIIATVTSSSENDDRSGSSLEWSKDGSLRAGAHRGIGHDRRTDNCSPVAEEEAVGSAENLPKEVPTGEGPVPYTQSSGSLIMPRPNSVAATSSTKLEDLSYLDGQRNAPLRTSIRLPWHNTAGGRVQQENKARFVTYKPQDILLKPLLFEVPSITTDSVFVGREWLFQAIEEKLKNTDLAESKGTVITGNVGFGKTAIISRLVALSCHGSRMRQIASNSPNSSPQSSDSCQEIPLSQLPLSTAPPSGTYTVKTMNCPGTPDNQNQTGDSVKRLASRVVAYHYCQADNTYTCLVPEFVHSIAALLCRSSQLTAYKDLLIKEPHLQSMLSLRSCVQDPAAAFKRGVLEPLSNLRKEQKIPEEEYIILIDGLNDAEFHKPDYGDTISSFLAKIICKFPPWLKLIVTVRTNFQEVARSLPFISISLDDFPDNKEIHNDLSAYIQYRINNSQEIINNISLNGKADAAIIGKVSNHLIMRSLGSYLYLKLTLDLFQKGHLVIKSASYKVVPVSLSELYLLQCNMKFMTNSAFERALPILNVALASLHPMTDEQIFQAINAGQINGEQQWEDFSQRMEALSCFLIKRRDKTRMFCHPSFREWLVWRADGENTDFLCEPRNGHALLAFMFSRQEGKLNRQQTMELGHHILKAHIFKGLSKRTGISSSHLQALWIGYSADGLSAALASLRNIYTPNVKVSRLLILAGANVNYKTEVLNNAPVLCVQSHLGHEEVVTLLLEYGAAIDGTSENGMTPLCYAAAAGHMNIVSLLCKKGAKADYLDKKGQCALVHSALRGHCDILEYLLNVAWAASSQEQNSLRKSQALQQSLTAASSMGHCQVVCYILAIEKEHEVDINVTDALWGETALTAAAGRGKLEVCELLLERGAAVSRANRRGVPPLFCAVRQGHWQIAKLLLEHGSDVNLSDKQGRTPLMVAACEGHLSTVEFLLSAGATISSLDKEGLTALGWACLKGHREVVQYLVEKGATVDQTDKNGRTPLDLAAFYGDADIVQYLVEKGAMIEHVDHSGMRPLDRAIGCRNTSVVVMLLRKGAKLGNAAWAMATSKPDILLILLQKLMEEGNILYKKGKMKEAAQRYQYALRKFPREGFGEEMKAFNEMRVSLYLNLSRCRRKTNDFGLAEEFATKALDLKPKSYEAYYARARAKRNSRKLLAALADLHEATKLCPGNQEIKRLLARVEEECKQFQRTQQQKHQCSQSGQQITNSDNEEEDVIQGVNENFHLQEKEEELPHPDESVSSPQRLQHSLATSSYTRNLQDSVQQKVRPVSPQGRTGNKYLREPGLIMQPTKQAQIVKTNQHLSSIQPGSKLGSSQCNTKTQSPFQHLSQSPVPVRHTKIQHLEGTSALSAGSVSTGASSELYNEKFTSSQCSHSQHSFAKKSKTTDPSPAPFQMNFSEARQQSPVPSTVSSTSPPSSMILASSTSSLTSVSSSADSIKGLGPDVRSKENKVNQVHGTAAEHRPRNTPFMGIMDKTARFQQQNQSSRSWHSQASDGLSTNVSSGSIQSSNFEQFSVKHSQTKTSSTVTIPGESNQNGMQAKVHEELRCQTAAYCQDNRAPKQVLHLYPDAPSKQHSHISKEGHLSHVTSTKPKRSFIESNV", "length": 1869, "header": "tr|A0A8V0YFL0-1|A0A8V0YFL0_CHICK Computationally mapped isoform of Tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 OS=Gallus gallus OX=9031 GN=TANC1 PE=1 SV=1 CANONICAL=A0A8V0YFN4-1" }, "locus": { "chromosome": "7", "start_pos": 36142090, "end_pos": 36084289, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026163.1", "url": "https://www.ensembl.org/id/ENSGALT00010026163.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010014787.1", "url": "https://www.ensembl.org/id/ENSGALP00010014787.1" } ] } }, { "isoform_ac": "A0A8V0YFM4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFN4/entry#A0A8V0YFM4-1", "sequence": { "sequence": "MARKTWVVPLPPAGGRAPSGATLKMLKAVLKKSREGGKGSKKESAGDSCPENALQSVAASGHGADLPTGNQHIPGDAYRMNLAKGVSMSLPSSPLLPRQSYLMQSRSNKKSPGPIRKAKYVESPRVPGEAILLLRKQSGQEEPIQNAKPDKDSSCSPAAQELMTRLGFLLGEGIPTSAHIEEKNESMCTIASQGVSPCSTLTSSTTSPSTDSPCSTLNSCTGKAAANKGSPCETMRSPSSTLESKDSGIIATVTSSSENDDRSGSSLEWSKDGSLRAGAHRGIGHDRRTDNCSPVAEEEAVGSAENLPKEVPTGEGPVPYTQSSGSLIMPRPNSVAATSSTKLEDLSYLDGQRNAPLRTSIRLPWHNTAGGRVQQENKARFVTYKPQDILLKPLLFEVPSITTDSVFVGREWLFQAIEEKLKNTDLAESKGTVITGNVGFGKTAIISRLVALSCHGSRMRQIASNSPNSSPQSSDSCQEIPLSQLPLSTAPPSGTYTVKTMNCPGTPDNQNQTGDSVKRLASRVVAYHYCQADNTYTCLVPEFVHSIAALLCRSSQLTAYKDLLIKEPHLQSMLSLRSCVQDPAAAFKRGVLEPLSNLRKEQKIPEEEYIILIDGLNDAEFHKPDYGDTISSFLAKIICKFPPWLKLIVTVRTNFQEVARSLPFISISLDDFPDNKEIHNDLSAYIQYRINNSQEIINNISLNGKADAAIIGKVSNHLIMRSLGSYLYLKLTLDLFQKGHLVIKSASYKVVPVSLSELYLLQCNMKFMTNSAFERALPILNVALASLHPMTDEQIFQAINAGQINGEQQWEDFSQRMEALSCFLIKRRDKTRMFCHPSFREWLVWRADGENTDFLCEPRNGHALLAFMFSRQEGKLNRQQTMELGHHILKAHIFKGLSKRTGISSSHLQALWIGYSADGLSAALASLRNIYTPNVKVSRLLILAGANVNYKTEVLNNAPVLCVQSHLGHEEVVTLLLEYGAAIDGTSENGMTPLCYAAAAGHMNIVSLLCKKGAKADYLDKKGQCALVHSALRGHCDILEYLLNVAWAASSQEQNSLRKSQALQQSLTAASSMGHCQVVCYILAIEKEHEVDINVTDALWGETALTAAAGRGKLEVCELLLERGAAVSRANRRGVPPLFCAVRQGHWQIAKLLLEHGSDVNLSDKQGRTPLMVAACEGHLSTVEFLLSAGATISSLDKEGLTALGWACLKGHREVVQYLVEKGATVDQTDKNGRTPLDLAAFYGDADIVQYLVEKGAMIEHVDHSGMRPLDRAIGCRNTSVVVMLLRKGAKLGNAAWAMATSKPDILLILLQKLMEEGNILYKKGKMKEAAQRYQYALRKFPREGFGEEMKAFNEMRVSLYLNLSRCRRKTNDFGLAEEFATKALDLKPKSYEAYYARARAKRNSRKLLAALADLHEATKLCPGNQEIKRLLARVEEECKQFQRTQQQKHQCSQSGQQITNSDNEEEDVIQGVNENFHLQEKEEELPHPDESVSSPQRLQHSLATSSYTRNLQDSVQQKVRPVSPQGRTGNKYLREPGLIMQPTKQAQIVKTNQHLSSIQPGSKLGSSQCNTKTQSPFQHLSQSPVPVRHTKIQHLEGTSALSAGSVSTGASSELYNEKFTSSQCSHSQHSFAKKSKTTDPSPAPFQMNFSEARQQSPVPSTVSSTSPPSSMILASSTSSLTSVSSSADSIKGLGPDVRSKENKVNQVHGTAAEHRPRNTPFMGIMDKTARFQQQNQSSRSWHSQASDGLSTNVSSGSIQSSNFEQFSVKHSQTKTSSTVTIPGESNQNGMQAKVHEELRCQTAAYCQDNRAPKQVLHLYPDAPSKQHSHISKEGHLSHVTSTKPKRSFIESNV", "length": 1854, "header": "tr|A0A8V0YFM4-1|A0A8V0YFM4_CHICK Computationally mapped isoform of Tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 OS=Gallus gallus OX=9031 GN=TANC1 PE=1 SV=1 CANONICAL=A0A8V0YFN4-1" }, "locus": { "chromosome": "7", "start_pos": 36142090, "end_pos": 36055548, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026178.1", "url": "https://www.ensembl.org/id/ENSGALT00010026178.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010014802.1", "url": "https://www.ensembl.org/id/ENSGALP00010014802.1" } ] } }, { "isoform_ac": "A0A8V0YFN4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFN4/entry#A0A8V0YFN4-1", "sequence": { "sequence": "MARKTWVVPLPPAGGRAPSVKAAGVRVSKKQEAVPAGTNTRPTGRDKASIVSISKIHHMDVMLRKCHRTWQQHTPLSSCGGNIDVQSQTEGATLKMLKAVLKKSREGGKGSKKESAGDSCPENALQSVAASGHGADLPTGNQHIPGDAYRMNLAKGVSMSLPSSPLLPRQSYLMQSRSNKKSPGPIRKAKYVESPRVPGEAILLLRKQSGQEEPIQNAKPDKDSSCSPAAQELMTRLGFLLGEGIPTSAHIEEKNESMCTIASQGVSPCSTLTSSTTSPSTDSPCSTLNSCTGKAAANKGSPCETMRSPSSTLESKDSGIIATVTSSSENDDRSGSSLEWSKDGSLRAGAHRGIGHDRRTDNCSPVAEEEAVGSAENLPKEVPTGEGPVPYTQSSGSLIMPRPNSVAATSSTKLEDLSYLDGQRNAPLRTSIRLPWHNTAGGRVQQENKARFVTYKPQDILLKPLLFEVPSITTDSVFVGREWLFQAIEEKLKNTDLAESKGTVITGNVGFGKTAIISRLVALSCHGSRMRQIASNSPNSSPQSSDSCQEIPLSQLPLSTAPPSGTYTVKTMNCPGTPDNQNQTGDSVKRLASRVVAYHYCQADNTYTCLVPEFVHSIAALLCRSSQLTAYKDLLIKEPHLQSMLSLRSCVQDPAAAFKRGVLEPLSNLRKEQKIPEEEYIILIDGLNDAEFHKPDYGDTISSFLAKIICKFPPWLKLIVTVRTNFQEVARSLPFISISLDDFPDNKEIHNDLSAYIQYRINNSQEIINNISLNGKADAAIIGKVSNHLIMRSLGSYLYLKLTLDLFQKGHLVIKSASYKVVPVSLSELYLLQCNMKFMTNSAFERALPILNVALASLHPMTDEQIFQAINAGQINGEQQWEDFSQRMEALSCFLIKRRDKTRMFCHPSFREWLVWRADGENTDFLCEPRNGHALLAFMFSRQEGKLNRQQTMELGHHILKAHIFKGLSKRTGISSSHLQALWIGYSADGLSAALASLRNIYTPNVKVSRLLILAGANVNYKTEVLNNAPVLCVQSHLGHEEVVTLLLEYGAAIDGTSENGMTPLCYAAAAGHMNIVSLLCKKGAKADYLDKKGQCALVHSALRGHCDILEYLLNVAWAASSQEQNSLRKSQALQQSLTAASSMGHCQVVCYILAIEKEHEVDINVTDALWGETALTAAAGRGKLEVCELLLERGAAVSRANRRGVPPLFCAVRQGHWQIAKLLLEHGSDVNLSDKQGRTPLMVAACEGHLSTVEFLLSAGATISSLDKEGLTALGWACLKGHREVVQYLVEKGATVDQTDKNGRTPLDLAAFYGDADIVQYLVEKGAMIEHVDHSGMRPLDRAIGCRNTSVVVMLLRKGAKLGNAAWAMATSKPDILLILLQKLMEEGNILYKKGKMKEAAQRYQYALRKFPREGFGEEMKAFNEMRVSLYLNLSRCRRKTNDFGLAEEFATKALDLKPKSYEAYYARARAKRNSRKLLAALADLHEATKLCPGNQEIKRLLARVEEECKQFQRTQQQKHQCSQSGQQITNSDNEEEDVIQGVNENFHLQEKEEELPHPDESVSSPQRLQHSLATSSYTRNLQDSVQQKVRPVSPQGRTGNKYLREPGLIMQPTKQAQIVKTNQHLSSIQPGSKLGSSQCNTKTQSPFQHLSQSPVPVRHTKIQHLEGTSALSAGSVSTGASSELYNEKFTSSQCSHSQHSFAKKSKTTDPSPAPFQMNFSEARQQSPVPSTVSSTSPPSSMILASSTSSLTSVSSSADSIKGLGPDVRSKENKVNQVHGTAAEHRPRNTPFMGIMDKTARFQQQNQSSRSWHSQASDGLSTNVSSGSIQSSNFEQFSVKHSQTKTSSTVTIPGESNQNGMQAKVHEELRCQTAAYCQDNRAPKQVLHLYPDAPSKQHSHISKEGHLSHVTSTKPKRSFIESNV", "length": 1925, "header": "tr|A0A8V0YFN4-1|A0A8V0YFN4_CHICK Isoform 1 of Tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 OS=Gallus gallus OX=9031 GN=TANC1 PE=1 SV=1 CANONICAL=A0A8V0YFN4-1" }, "locus": { "chromosome": "7", "start_pos": 36142090, "end_pos": 36055548, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026188.1", "url": "https://www.ensembl.org/id/ENSGALT00010026188.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010014812.1", "url": "https://www.ensembl.org/id/ENSGALP00010014812.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "G3X6E6-1", "protein_name": "Tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1", "gene_name": "TANC1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MLKAVLKKSREGGKGSKKETGGDFGPETSPPVLPPGHGGEFSVSSLPVAEDAYRVSLAKGVSMSLPSSPLLPRQSHSVPSRSTKKSPGPVRKPKYVESPRVPGDAVIIPFRDVPKPAEPSENEAKADNEPSCSPAAQELLTRLGFLLGEGIPSATHITIEEKNETMCTALSQGISPCSTLTSSTASPSTDSPCSTLNSCVSKTAANKSPCETISSPSSTLESKDSGIIATITSSSENDDRSGSSLEWNKDGSLRLGVQKGVLHDRRADNCSPVAEEEPPGPAESVLPKAEASVGDGPVPYSQSSSSLIMPRPNSVAATSSTKLEDLSYLDGQRNAPLRTSIRLPWHNTAGGRAQEVKARFAPYKPQDILLKPLLFEVPSITTDSVFVGRDWLFHQIEENLRNTELTENRGAVVVGNVGFGKTAIISKLVALSCHGSRMRQIASNSPSSSTKTSDSSQDVPFTPLLSPTSSTSGSGAAKSPPVSGSDPENQRPREDSVKYLASKVVAYHYCQADNTYTCLVPEFVHSIAALLCRSHQLAAYRDLLIREPQLQSMLSLRSCVQDPVAAFKRGVLEPLTSLRNEQKIPEEEYIILIDGLNEAEFHKPDYGDTLSSFITKIISKFPAWLKLIVTVRANFQEIVSELPFVKLSLDDFPDNKDIHSDLHAYVQHRVHSSQDILSNISLNGKADAALIGKVSSHLVLRSLGSYLYLKLTLDLFQRGHLVIKSASYKVVPVSLSELYLLQCNMKFMTQSAFERALPILNVALASLHPMTDEQIFQAINAGHVQGEQGWEDFQQRMDALSCFLIKRRDKTRMFCHPSFREWLVWRADGENTAFLCEPRNGHALLAFMFSRQEGKLNRQQTMELGHHILKAHIFKGLSKKTGISSSHLQALWIGYSTEGLSAALASLRNLYTPNVKVSRLLILGGANVNYRTEVLNNAPILCVQSHLGHEEVVTLLLEFGACLDGMSENGMTALCYAAAAGHMKLVCLLAKKGARVDHLDKKGQCALVHSALRGHGDVLRYLLTCEWSLGPPQPGALRKSQALQQALTAAASMGHGSVLQCLLELEKEHEIDVNGTDTLWGETALTAAAGRGKLEVCELLLERGAAVSRTNRRGVPPLFCAARQGHWQIVRLLLDHGCDVNLSDKQGRTPLMVAACEGHLSTVEFLLSKGATLSSLDKEGLSALSWACLKGHRAVVQFLVEEGAEIDQTDKNGRSPLDLAAFYGDAETVLYLVDKGAVIEHVDHSGMRPLDRAIGCRNTSVVVTLLRKGAKLGNAAWAMATSKPDILIILLQKLMEEGNVMYKKGKMKEAAQRYQYALRKFPREGFGEDMRPFNELRVSLYLNLSRCRRKTNDFGMAEEFASKALELKPKSYEAFYARARAKRSSRQFVAALADLREAVKLCPANQEIRRLLARVEEECKQLQRSQQQKQQAPPPAPPTDSDNEEYAPTPGLNDHFHLEGAEEEETSPPEEAVSLAPRPPPSSSAPSPYIRNLQEGLQPKIRPVSPLQSRPGAGKALREAVAQPGLTVQPTKQAQIVKTSQHLGSGPAGVRNSSSKTQVSPLNPPPSPMPGRLPTAPAGSRSLHLEGAASGPFGDRLGPSPAVHLQHSEGDAAYPLPSKIKSAERLLSHAAVAVDVVPLNPGGPVSCSDTRHPTSLSSSGSSGSPSSSIKMSSSTSSLASSSSFSDGFKVQGPDARIKDKVGSQVPSGTAEHRPRNTPFMGIMDKTARFQQQNHPPGRTWHCAVSEGLLTGTPSAAGLQASNSEKPSLKQAKACPGSTLGGGVHNGAQVKEPEEKKCQMPVHCQDSRVTKTISHLYQESMSKQQSHISSEAHRSHLPSAKPKRSFIESNV", "length": 1850 }, "evidence": [ { "id": "A0A8V0YFN4", "url": "https://omabrowser.org/oma/group/A0A8V0YFN4/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q0VGY8-1", "protein_name": "Protein TANC1", "gene_name": "Tanc1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLKAVLKKSREGGKGSKKEAGGDFGSETPALSSSGDSPVNSLSTTEDTYRVSLAKGVSMSLPSSPLLPRQSLLTQSRSNKKSPGPVRKPKYVESPRVPGDPVMIPFGEGSKPSEPSATEAKADNEPSCSPAAQELLTRLGFLLGEGIPSATHITIEDKNEAMCTALSQGISPCSTLTSSTASPSTDSPCSTLNSCVSKTAASKSPCETISSPSSTLESKDSGIIATITSSSENDDRSGSSLEWNRDGSLRLGVQKGVLHDRRADNCSPVAEEETTGSAESVLPKAEPSAGDGPVPYPQSSGSLIMPRPNSVAATSSTKLEDLSYLDGQRNAPLRTSIRLPWHNTAGGRAPEVKARFAPYKPQEILLKPLLFEVPSITTDSVFVGRDWLFHQIEENLRNTELAENRGAVVVGSVGFGKTAIISKLVALSCHGSRMRQIASSSPSLSPKSSDPTQDLPGTPLLSPSSSTSALSVTRTPAGPGTADSQRPREDAVKYLASKVVAYHYCQADNTYTCLVPEFVHSIAALLCRSHQLAAYRDLLIKEPQLQSMLSLRSCVQDPVAAFKRGVLEPLTSLRNEQKIPEEEYIILIDGLNEAEFHKPDYGDTLSSFITKIIPKFPTWLKLIVTVRANFQEIISALPFVKLSLDDFPDNKDIHSDLHAYVQHRVHSSQDILSNISLNGKADAALISKVSSHLVLRSLGSYLYLKLTLDLFQRGHLVIKSASYKVVPVSLSELYLLQCNMKFMTQSAFDRALPILNVALASLHPMTDEQIFQAINAGHIQGEQGWEDFQQRMEALSCFLIKRRDKTRMFCHPSFREWLVWRADGESTAFLCEPRNGHALLAFMFSRQESKLNRQQTMELGHHILKAHIFKGLSKKTGVSSSHLQALWIGYSTEGLSAALASLRNLYTPNVKVSRLLILGGANVNYRTEVLNNAPILCVQSHLGHEEVVTLLLEFGACLDGMSENGMNALCYAAAAGHMKLVCLLIKKGARVDHLDKKGQCALVHSALRGHSDILQYLLNCEWSAGPPQPGTLRKSQALQQALTAAASMGHSSVVQSLLGMAEEHEIEVNGTDTLWGETALTAAAGRGKVEICELLLERGAAVSRANRRGVPPLFCAARQGHWQVVRLLLDRGCDVNLSDKQGRTPLMVASCEGHLSTVEFLLSKGAALSSLDKEGLSALSWACLKGHRAVVQYLVEEGAEIDQTDKNGRTPLDLAAFYGDAETVLYLVEKGAVIEHVDHSGMRPLDRAIGCRNTAVVVTLLRKGAKLGNAAWAMATSKPDILIILLQKLVEEGNVMYKKGKMKEAAQRYQYALRKFPREGLGEDMRPFNELRVSLYLNLSRCRRKTNDFGLAEEFASKALELKPKSYEAFYARARAKRNSRQFLAALADLQEAVKLCPNNQEIKRLLARVEEECKQLQRNQQQKQQGPPPAPANDSDNEEDAPASSLKDHFPIEEAEEEDTSSQEESISPTPRSQPPPSVPSPYIRNLQEGLQSKGRSASPQSRAGISKSLRETVAQSGLVMQPTKQAQIVKTNQHLGSGQSSMRNSSTKIQVSSQNPPPSPMPGRVSAAPAVSRNQHLEGTGPFTAGTGCGHFGDRLGASQSLQLQRSESGTAYPLPSKVKAAERLLAHASVAVDMAPPNQGGPVSCSDVRHPASLSSSGSSGSPSSSIKMSSSTSSLTSSSSVSDGFKVQGPDSRIRDKGTTQVQGGTAEHRPRNTPFMGIMDKTARFQQQSNPPNRSWHCPVAEGLLTNTATAAGLQSNSEKPTLKPGGYCSQAKPCSVPPLSMGVHNGAQVKELEENKCQIPALCQDNRITKGVPHLYPEGVSKQPLHVSTEAHRSHLTSAKPKRSFIESNV", "length": 1856 }, "evidence": [ { "id": "A0A8V0YFN4", "url": "https://omabrowser.org/oma/group/A0A8V0YFN4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q6F6B3-1", "protein_name": "Protein TANC1", "gene_name": "Tanc1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLKAVLKKSREGVKGSKKEAGGDFGSETPTLSSSGDSPVNSLSTTEDTYRVSLAKGVSMSLPSSPLLPRQSHLTQSRANKKSPGPVRKPKYVESPRVPGDPVMIPFREGSKPAEPIETEAKVDNEPSCSPAAQELLTRLGFLLGEGIPSATHITIEDKNEAMCTALSQGISPCSTLTSSTASPSTDSPCSTLNSCVSKTAANKSPCETISSPSSTLESKDSGIIATITSSSENDDRSGSSLEWNRDGSLRLGVQKGVLHDRRLDNCSPVAEEETTGSAESVLPKAESSAGDGPVPYSQSSGSLIMPRPNSVAATSSTKLEDLSYLDGQRNAPLRTSIRLPWHSTAGARFAPYKPQEILLKPLLFEVPSITTDSVFVGRDWLFQQIEENLRNTELAENRGAVVVGNVGFGKTAIISKLVALSCHGSRMRQVASSSPSSSLKTSDPTHDLPGTPLLSPSSSTSALSAARTPPGPGTVDSQRPREDAVKYLASRVVAYHYCQADNTYTCLVPEFVHSIATLLCRSHQLAAYRDLLIREPQLQSMLNLRSCVQDPVAAFKRGILEPLTNLRNEQKIPEEEYIILIDGLNEAEFHKPDHGDTLSSFITKIIPKFPPWLKLIVTVRADFQEIISTLPFVKLSLDDFPGNQDIHSDLHAYVQHRVHSSQDILSNISLNGKADAALIGKVSSRLVLRNLGSYLYLKLTLDLFQRGHLVIKSASYKVVPVSLSELYLLQCNMKFMTQSAFDRALPILNVALASLHPMTDEQIFQAINAGHIQGEQGWEDFQQKMEALSCFLIKKRDKTRMFCHPSFREWLVWRADGESTAFLCEPRNGHALLAFMFSRQESKLNRQQTVELGHHILKAHIFKGLSKKTGVSSSHPQALWIGYSTEGLSAALASLRNLYTPNVKVSRLLILGGANVNYRTEVLNNAPILCVQSHLGHEEVVTLLLEFGACLDGMSENGMNALCYAAAAGHMKLVCLLTKKGARVDHLDKKGQCALVHSALRGHSDILQYLLNCEWSAGPPQPGTLRKSQALQQALTAAASMGHSAVVQSLLGMAEEHEIEVNGTDTLWGETALTAAAGRGKLEICELLLERGAAVSRANRRGVPPLFCAARQGHWQVVQLLLDRGCDVNPNDKQGRTPLMVAACEGHLSTVEFLLSKGAALSSLDKEGLSALSWACLKGHRAVVQYLVEEGAEIDQTDKNGRTPLDLAAFYGDAETVLYLVEKGAVIEHVDHSGMRPLDRAIGCRNTAVVVTLLRKGAKLGNAAWAMATFKPDILIILLQKLMEEGNVMYKKGKMKEAAQRYQYALRKFPREGPGEDMRPFNELRVSLYLNLSRCRRKTNDFGLAEEFASKALELKPKSYEAFYARARAKRNSRQFLAALADLQEAVKLCPTNQEIKRLLARVEEECKQLQRNQQQKQQAPLPAPPNDSDNDEEAPASSLKDHFPIEEAEEEDTSSQEESISPTPRSQPPPSVPSPYIRNLQEGLQSKGRPASPQSWAGISKSLRETVAQPGLVMQPTKQAQIVKTNQHLGSGQSSMRNSNTKVQVSSQNPPPSPMPGRVSAAPAVSRNQHLEGTGPFSTGTGCGHFGDRLGPSQSLQLQRGESGTAYPLPSKVKAAERLLAHASVAVDMALPSQGGPVSCSDVRHPASLSSSGSSGSPSSSVKMSSSTSSLTSSSSVSDGFKAQGPDCRIRDRGTTQVQGGTAEHRPRNTPFMGIMDKIARFQQQVNPPSRSWHCPVTEGLLTNTATAAGLQTNSEKPALKPGGYCSQAKPCSVPPLGMGVHNGAQVKELEENKCQVPALCQDNRKTKGVPHLYPEGVSKQPLHVSTEAHRSHLTSAKPKRSFIESNV", "length": 1849 }, "evidence": [ { "id": "A0A8V0YFN4", "url": "https://omabrowser.org/oma/group/A0A8V0YFN4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9C0D5-1", "protein_name": "Protein TANC1", "gene_name": "TANC1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLKAVLKKSREGGKGGKKEAGSDFGPETSPVLHLDHSADSPVSSLPTAEDTYRVSLAKGVSMSLPSSPLLPRQSHLVQSRVNKKSPGPVRKPKYVESPRVPGDAVIMPFREVAKPTEPDEHEAKADNEPSCSPAAQELLTRLGFLLGEGIPSATHITIEDKNETMCTALSQGISPCSTLTSSTASPSTDSPCSTLNSCVSKTAANKSPCETISSPSSTLESKDSGIIATITSSSENDDRSGSSLEWNKDGNLRLGVQKGVLHDRRADNCSPVAEEETTGSAESTLPKAESSAGDGPVPYSQGSSSLIMPRPNSVAATSSTKLEDLSYLDGQRNAPLRTSIRLPWHNTAGGRAQEVKARFAPYKPQDILLKPLLFEVPSITTDSVFVGRDWLFHQIEENLRNTELAENRGAVVVGNVGFGKTAIISKLVALSCHGSRMRQIASNSPGSSPKTSDPTQDLHFTPLLSPSSSTSASSTAKTPLGSISAENQRPREDAVKYLASKVVAYHYCQADNTYTCLVPEFVHSIAALLCRSHQLAAYRDLLIKEPQLQSMLSLRSCVQDPVAAFKRGVLEPLTNLRNEQKIPEEEYIILIDGLNEAEFHKPDYGDTLSSFITKIISKFPAWLKLIVTVRANFQEIISALPFVKLSLDDFPDNKDIHSDLHAYVQHRVHSSQDILSNISLNGKADATLIGKVSSHLVLRSLGSYLYLKLTLDLFQRGHLVIKSASYKVVPVSLSELYLLQCNMKFMTQSAFERALPILNVALASLHPMTDEQIFQAINAGHIQGEQGWEDFQQRMDALSCFLIKRRDKTRMFCHPSFREWLVWRADGENTAFLCEPRNGHALLAFMFSRQEGKLNRQQTMELGHHILKAHIFKGLSKKTGISSSHLQALWIGYSTEGLSAALASLRNLYTPNVKVSRLLILGGANVNYRTEVLNNAPILCVQSHLGHEEVVTLLLEFGACLDGTSENGMTALCYAAAAGHMKLVCLLTKKGVRVDHLDKKGQCALVHSALRGHGDILQYLLTCEWSPGPPQPGTLRKSHALQQALTAAASMGHSSVVQCLLGMEKEHEVEVNGTDTLWGETALTAAAGRGKLEVCELLLGHGAAVSRTNRRGVPPLFCAARQGHWQIVRLLLERGCDVNLSDKQGRTPLMVAACEGHLSTVEFLLSKGAALSSLDKEGLSALSWACLKGHRAVVQYLVEEGAAIDQTDKNGRTPLDLAAFYGDAETVLYLVEKGAVIEHVDHSGMRPLDRAIGCRNTSVVVALLRKGAKLGNAAWAMATSKPDILIILLQKLMEEGNVMYKKGKMKEAAQRYQYALRKFPREGFGEDMRPFNELRVSLYLNLSRCRRKTNDFGMAEEFASKALELKPKSYEAFYARARAKRNSRQFVAALADLQEAVKLCPTNQEVKRLLARVEEECKQLQRSQQQKQQGPLPAPLNDSENEEDTPTPGLSDHFHSEETEEEETSPQEESVSPTPRSQPSSSVPSSYIRNLQEGLQSKGRPVSPQSRAGIGKSLREPVAQPGLLLQPSKQAQIVKTSQHLGSGQSAVRNGSMKVQISSQNPPPSPMPGRIAATPAGSRTQHLEGTGTFTTRAGCGHFGDRLGPSQNVRLQCGENGPAHPLPSKTKTTERLLSHSSVAVDAAPPNQGGLATCSDVRHPASLTSSGSSGSPSSSIKMSSSTSSLTSSSSFSDGFKVQGPDTRIKDKVVTHVQSGTAEHRPRNTPFMGIMDKTARFQQQSNPPSRSWHCPAPEGLLTNTSSAAGLQSANTEKPSLMQVGGYNNQAKTCSVSTLSASVHNGAQVKELEESKCQIPVHSQENRITKTVSHLYQESISKQQPHISNEAHRSHLTAAKPKRSFIESNV", "length": 1861 }, "evidence": [ { "id": "A0A8V0YFN4", "url": "https://omabrowser.org/oma/group/A0A8V0YFN4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "postsynapse", "id": "GO:0098794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098794", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFN4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFN4" } ], "pmid": "" }, { "name": "glutamatergic synapse", "id": "GO:0098978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098978", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFN4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFN4" } ], "pmid": "" }, { "name": "dendrite", "id": "GO:0030425", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030425", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFN4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFN4" } ], "pmid": "" }, { "name": "neuronal cell body", "id": "GO:0043025", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043025", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFN4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFN4" } ], "pmid": "" }, { "name": "axon terminus", "id": "GO:0043679", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043679", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFN4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFN4" } ], "pmid": "" }, { "name": "postsynaptic density, intracellular component", "id": "GO:0099092", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099092", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFN4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFN4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "regulation of postsynapse organization", "id": "GO:0099175", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099175", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFN4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFN4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1165, "end_pos": 1167, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1232, "end_pos": 1234, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1349, "end_pos": 1351, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1434, "end_pos": 1436, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1720, "end_pos": 1722, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1807, "end_pos": 1809, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1824, "end_pos": 1826, "annotation": "n_glycosylation_sequon" }, { "start_pos": 255, "end_pos": 257, "annotation": "n_glycosylation_sequon" }, { "start_pos": 362, "end_pos": 364, "annotation": "n_glycosylation_sequon" }, { "start_pos": 539, "end_pos": 541, "annotation": "n_glycosylation_sequon" }, { "start_pos": 582, "end_pos": 584, "annotation": "n_glycosylation_sequon" }, { "start_pos": 762, "end_pos": 764, "annotation": "n_glycosylation_sequon" }, { "start_pos": 770, "end_pos": 772, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YFN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFN4" }, { "id": "PF25520", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25520" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "TANC1/2-like AAA+ ATPase lid", "eco_id": "ECO_0000259", "start_pos": 740, "end_pos": 835, "start_aa": "Leu", "end_aa": "Asn", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0YFN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFN4" }, { "id": "PF25521", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25521" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "TANC1/2-like winged helix", "eco_id": "ECO_0000259", "start_pos": 837, "end_pos": 989, "start_aa": "Lys", "end_aa": "Asp", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1165, "end_pos": 1167 }, { "start_pos": 1232, "end_pos": 1234 }, { "start_pos": 1349, "end_pos": 1351 }, { "start_pos": 1434, "end_pos": 1436 }, { "start_pos": 1720, "end_pos": 1722 }, { "start_pos": 1807, "end_pos": 1809 }, { "start_pos": 1824, "end_pos": 1826 }, { "start_pos": 255, "end_pos": 257 }, { "start_pos": 362, "end_pos": 364 }, { "start_pos": 539, "end_pos": 541 }, { "start_pos": 582, "end_pos": 584 }, { "start_pos": 762, "end_pos": 764 }, { "start_pos": 770, "end_pos": 772 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YFJ0-1", "uniprot_ac": "A0A8V0YFJ0", "uniprot_id": "A0A8V0YFJ0_CHICK", "mass": { "chemical_mass": 61606.0, "monoisotopic_mass": 61606.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Uncharacterized protein", "type": "synonym", "evidence": [ { "id": "A0A8V0YFJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFJ0/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFJ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFJ0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFJ0", "locus": {} } ], "crossref": [ { "id": "A0A8V0YFJ0", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YFJ0", "database": "AlphaFoldDB", "categories": [] }, { "id": "PTHR35001", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR35001", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR35001:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR35001:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YAA2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAA2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YAA2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAA2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YFJ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFJ0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YFJ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFJ0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YGL1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGL1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YGL1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGL1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YNG5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNG5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YNG5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNG5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGKERVGKERKGKERVGKERVGKERKGKGGKGKERKGWERKGKERKGKERVGKGGKGKGGKGKERVGKERKGWERKGWERKGIERKGKERKGKERKGKERNGKERNGKERKGKGGKGKERVGKERKGWERKGKGGKGKERVGKERKGWERKGWERKGKGGKGKERKGKERKGKERKGWERKGKERKGKDRKGKERKGKERKGKERKGKGGKGKERRGKGGKGKEKERVGKERKGWERKGKGGKGKERKGKERKGKERKGKERKGKGGKGKERVGKERKGKERKGKERKGKERKGKERKGKERKGKERKGKERKGKERKGKERKGKGKERKGKERKGKERKGKERKGKKRKGWERKGKERVGKERKGKERKGKERKGKERKGKERKGKERVGKERKGKGGKGKERKGKERKGKERKGKERKGWERKGKERKGWERKGKERVGKERKGWERKGKGGKGKGGKEKERKGKERKGKERKGKERKGKERKGKERKGKERKGKERKGKERKGKERKGKERVGKERKGWERKGKGGKK", "length": 531, "header": "tr|A0A8V0YFJ0-1|A0A8V0YFJ0_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0YFJ0-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YAA2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFJ0/entry#A0A8V0YAA2-1", "sequence": { "sequence": "KERKGGKGKGGKGKERVGKERVGKERKGWERKGKGGKGKGGKGKGGKGKERKGKERKGWERVGKERVGKERKGWERKGKERKGKERKGKERKGKERNGKERNGKERKGKGGKGKERVGKERKGWERKGKGGKGKERVGKERKGWERKGWERKGKGGKGKERKGKERKGKERKGWERKGKERKGKDRKGKERKGKERKGKERKGKGGKGKERRGKGGKGKEKERVGKERKGWERKGKGGKGKERKGKERKGKERKGKERKGKGGKGKERVGKERKGKERKGKERKGKERKGKERKGKERKGKERKGKERKGKERKGKERKGKGKERKGKERKGKERKGKERKGKKRKGWERKGKERVGKERKGKERKGKERKGKERKGKERKGKERVGKERKGKGGKGKERKGKERKGKERKGKERKGWERKGKERKGWERKGKERVGKERKGWERKGKGGKGKGGKEKERKGKERKGKERKGKERKGKERKGKERKGKERKGKERKGKERKGKERKGKERVGKERKGWERKGKGGKK", "length": 527, "header": "tr|A0A8V0YAA2-1|A0A8V0YAA2_CHICK Computationally mapped isoform of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0YFJ0-1" }, "locus": { "chromosome": "W", "start_pos": 6124128, "end_pos": 6122078, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030444.1", "url": "https://www.ensembl.org/id/ENSGALT00010030444.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017659.1", "url": "https://www.ensembl.org/id/ENSGALP00010017659.1" } ] } }, { "isoform_ac": "A0A8V0YFJ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFJ0/entry#A0A8V0YFJ0-1", "sequence": { "sequence": "MGKERVGKERKGKERVGKERVGKERKGKGGKGKERKGWERKGKERKGKERVGKGGKGKGGKGKERVGKERKGWERKGWERKGIERKGKERKGKERKGKERNGKERNGKERKGKGGKGKERVGKERKGWERKGKGGKGKERVGKERKGWERKGWERKGKGGKGKERKGKERKGKERKGWERKGKERKGKDRKGKERKGKERKGKERKGKGGKGKERRGKGGKGKEKERVGKERKGWERKGKGGKGKERKGKERKGKERKGKERKGKGGKGKERVGKERKGKERKGKERKGKERKGKERKGKERKGKERKGKERKGKERKGKERKGKGKERKGKERKGKERKGKERKGKKRKGWERKGKERVGKERKGKERKGKERKGKERKGKERKGKERVGKERKGKGGKGKERKGKERKGKERKGKERKGWERKGKERKGWERKGKERVGKERKGWERKGKGGKGKGGKEKERKGKERKGKERKGKERKGKERKGKERKGKERKGKERKGKERKGKERKGKERVGKERKGWERKGKGGKK", "length": 531, "header": "tr|A0A8V0YFJ0-1|A0A8V0YFJ0_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0YFJ0-1" }, "locus": { "chromosome": "W", "start_pos": 6123750, "end_pos": 6122078, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030443.1", "url": "https://www.ensembl.org/id/ENSGALT00010030443.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017658.1", "url": "https://www.ensembl.org/id/ENSGALP00010017658.1" } ] } }, { "isoform_ac": "A0A8V0YGL1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFJ0/entry#A0A8V0YGL1-1", "sequence": { "sequence": "KGKEGWERKGWERKGKGGKGKGGKGKERVGKERKGWERKGWERKGWERKGKERKGKERKGKERKGKERNGKERNGKERKGKGGKGKERVGKERKGWERKGKGGKGKERVGKERKGWERKGWERKGKGGKGKERKGKERKGKERKGWERKGKERKGKDRKGKERKGKERKGKERKGKGGKGKERRGKGGKGKEKERVGKERKGWERKGKGGKGKERKGKERKGKERKGKERKGKGGKGKERVGKERKGKERKGKERKGKERKGKERKGKERKGKERKGKERKGKERKGKERKGKGKERKGKERKGKERKGKERKGKKRKGWERKGKERVGKERKGKERKGKERKGKERKGKERKGKERVGKGGKGWERKGKERVGKERKGKERKGKERKGKERKGKGGKGKERKGKGGKGKERKGWERKGKGGKGKERVGKERVGKKRKGKERKGKERKGKERKGKERKGKERKGKERKGKERKGKERKGKERKGKERKGWERKGKGGKGKERVGKK", "length": 506, "header": "tr|A0A8V0YGL1-1|A0A8V0YGL1_CHICK Computationally mapped isoform of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0YFJ0-1" }, "locus": { "chromosome": "W", "start_pos": 6124129, "end_pos": 6122077, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030447.1", "url": "https://www.ensembl.org/id/ENSGALT00010030447.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017661.1", "url": "https://www.ensembl.org/id/ENSGALP00010017661.1" } ] } }, { "isoform_ac": "A0A8V0YNG5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFJ0/entry#A0A8V0YNG5-1", "sequence": { "sequence": "KGKEGWERKGWERKGKGGKGKGGKGKERVGKERKGWERKGWERKGWERKGKERKGKERKGKERKGKERNGKERNGKERKGKGGKGKERVGKERKGWERKGKGGKGKERVGKERKGWERKGWERKGKGGKGKERKGKERKGKERKGKGKGGKGKERVGKERKGKERKGKERKGKERKGKERVGKERKGWERKGKERKGKERKGKERKGKERKGKERKGKERKGKERKGKERKGKERKGKEKERKGKERKGKERKGKERKGKERKGKGGKGKERKGWERKGKERKGKERKGKERKGKERKGKERKGWERVGKGGKGKERKGWERKGKERKGKERKGKERKGKERVGKERKGKERVGKERKGKGGKGKERVGKERKGWERKGWERKGKERKGKERKGKERKGKERKGKERKGKERKGKERKGKERKGKERKGKERKGKGGKGKERVGKERKGWE", "length": 451, "header": "tr|A0A8V0YNG5-1|A0A8V0YNG5_CHICK Computationally mapped isoform of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0YFJ0-1" }, "locus": { "chromosome": "W", "start_pos": 6124129, "end_pos": 6122082, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030445.1", "url": "https://www.ensembl.org/id/ENSGALT00010030445.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017660.1", "url": "https://www.ensembl.org/id/ENSGALP00010017660.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YFJ5-1", "uniprot_ac": "A0A8V0YFJ5", "uniprot_id": "A0A8V0YFJ5_CHICK", "mass": { "chemical_mass": 97130.0, "monoisotopic_mass": 97130.0 }, "refseq": { "ac": "NP_001305937", "name": "aryl hydrocarbon receptor 2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001305937" }, "gene_names": [ { "name": "AHR2", "type": "recommended", "evidence": [ { "id": "A0A8V0YFJ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFJ5" } ] }, { "name": "AHR2", "type": "synonym", "evidence": [ { "id": "NP_001305937", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001305937" } ] } ], "protein_names": [ { "name": "Aryl hydrocarbon receptor 2", "type": "synonym", "evidence": [ { "id": "A0A8V0YFJ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFJ5/entry#names_and_taxonomy" } ] }, { "name": "aryl hydrocarbon receptor 2", "type": "synonym", "evidence": [ { "id": "NP_001305937", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001305937" } ] }, { "name": "aryl hydrocarbon receptor-like", "type": "synonym", "evidence": [ { "id": "NP_001305937", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001305937" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: KM289156.1, SRR13267661.18647.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000235.1. On Nov 27, 2021 this sequence version replaced NP_001305937.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001305937", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001305937" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFJ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFJ5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "AHR2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFJ5", "locus": { "chromosome": "7", "start_pos": 6655525, "end_pos": 6632099, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013824", "url": "https://www.ensembl.org/id/ENSGALG00010013824" } ] } } ], "crossref": [ { "id": "A0A8V0YFJ5", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YFJ5", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00130", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00130", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd19696", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd19696", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "424033", "url": "https://www.ncbi.nlm.nih.gov/gene/424033", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000014", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000014", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001610", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001610", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011598", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011598", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013655", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013655", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013767", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013767", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035965", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035965", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036638", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036638", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039091", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039091", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:424033", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424033", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YFJ5", "url": "https://www.orthodb.org/?gene=A0A8V0YFJ5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YLH2", "url": "https://www.orthodb.org/?gene=A0A8V0YLH2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10649", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10649", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10649:SF17", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10649:SF17", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00010", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00010", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00989", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00989", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08447", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08447", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001305937", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001305937", 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OS=Gallus gallus OX=9031 GN=AHR2 PE=4 SV=1 CANONICAL=A0A8V0YFJ5-1" }, "locus": { "chromosome": "7", "start_pos": 6654819, "end_pos": 6632114, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033189.1", "url": "https://www.ensembl.org/id/ENSGALT00010033189.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019611.1", "url": "https://www.ensembl.org/id/ENSGALP00010019611.1" } ] } }, { "isoform_ac": "A0A8V0YLH2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFJ5/entry#A0A8V0YLH2-1", "sequence": { "sequence": "MAAVTSSLGLETACWTHLIKLCFAFSSPKPSPPEGVKSNPSKRHRDRLNEELNKLTGLLPFPEDACTRFDKLSTLRLAVGYLKVKNYLMAAGTDVGMLDQPRAPGGNGQTHLQVNRDPFPEGDLLLQALNGFVITVTADGYIFYISPTVQNYLGFHQSDLIYQSIYELIHKDDRAAFHCQLHDAVPDGCSAVGSPNHRCPERFGCMERNFTCRLRCLLDNSSGFLALNFQGRLKQLLGQQKRASDMSLEPLPLALFAIVTPFQPFSILKLQTKMLFFQSKHKLDFTPIACDSWYGISCLHSESLCHFSFLPAPVIKTGQTGTTVFRLLTKNGSWVWLQATAWLVYKGDEPDCIISRQRVLSNEEGEEHLRKRNLQLPFSFATGEAILYGNNFPDFLGSFQAKEEFQTKTDSHTVQHAIYPNSITGAMMEQDTSIHLSHTDVPQFTLPDLDAEPDGPSQDGKVGHDKDSSSLLVAIETLFEKSEVDGNISQSLTVGSTELQKWEDTLLSLDMEELPSEDFGERLSSELPSYTEQMLFREGDGKSMEFLHCSEEDCSVAQFQHWGFNPEVPQAFQAPWQPQAAGAQGQDAVLSLGSVMPEGSSAPVEQQILINPASLKEGMLLDALGFSSKPCAVDQLVNSGLEFQAGLPTSIPIDTIIPDCQSQSECTLTGVSCLPPLDSSTLVSQWHDVPVWAKLGSTLGQSTSPGGCPLDAWMTAPEQLEATGASLESQIALNSSSQSWGSFPRQPHCNGEQVLLSKDAWPQPQGLVLGINVCPGTHQTDNIMLHHYEYRTSQGVFRHGNSFLGDAIKTPTSALPCTNHPGTSTGLSSSCSASPSAEVGARASPCELDSVFPLSSLAGRQPLCACHVQLKVWGGDCRT", "length": 879, "header": "tr|A0A8V0YLH2-1|A0A8V0YLH2_CHICK Computationally mapped isoform of Aryl hydrocarbon receptor 2 OS=Gallus gallus OX=9031 GN=AHR2 PE=4 SV=1 CANONICAL=A0A8V0YFJ5-1" }, "locus": { "chromosome": "7", "start_pos": 6654819, "end_pos": 6635298, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033180.1", "url": "https://www.ensembl.org/id/ENSGALT00010033180.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019605.1", "url": "https://www.ensembl.org/id/ENSGALP00010019605.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 142, "start_aa": "Thr", "end_pos": 142, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr142", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": 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Function", "total": 4, "go_terms": [ { "name": "protein dimerization activity", "id": "GO:0046983", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046983", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFJ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFJ5" } ], "pmid": "" }, { "name": "transcription cis-regulatory region binding", "id": "GO:0000976", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000976", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFJ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFJ5" } ], "pmid": "" }, { "name": "nuclear receptor activity", "id": "GO:0004879", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004879", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFJ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFJ5" } ], "pmid": "" }, { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFJ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFJ5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 203, "end_pos": 205, "annotation": "n_glycosylation_sequon" }, { "start_pos": 214, "end_pos": 216, "annotation": "n_glycosylation_sequon" }, { "start_pos": 341, "end_pos": 343, "annotation": "n_glycosylation_sequon" }, { "start_pos": 497, "end_pos": 499, "annotation": "n_glycosylation_sequon" }, { "start_pos": 744, "end_pos": 746, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YFJ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFJ5" }, { "id": "PS50888", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50888" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "BHLH", "eco_id": "ECO_0000259", 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"end_pos": 746 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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"database": "AlphaFoldDB", "categories": [] }, { "id": "IPR000504", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000504", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012677", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012677", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y754", "url": "https://www.orthodb.org/?gene=A0A8V0Y754", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YFK6", "url": "https://www.orthodb.org/?gene=A0A8V0YFK6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21245", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21245", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00076", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00076", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14709", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14709", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0Y754", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y754", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y754-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y754-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YFK6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFK6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YFK6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFK6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPVVGQLGALPGPALTSLLPPQQWTSSINRTNKMALLAWVRETGIDLVQVNGQRRYGGPPPGWVGSPPPPGSEVYIAKLPRDLYEDTLIPLFQSVGQLYEFRLMLTFSGLNRGFAYAKYSDQHGAGKAIAALNNWEVQEGRAILVCRSFEKCELSVNGLPATLRRRELDTMLLEATEGLLGLTLHASPGRKQGKVAVLTYSSHRAAAMAKKALVEGNVGLFKKKVKVEWLKPELKEQLQACGEKPPPGSVQCLQSPERVLPSSELRGALGRLGALCRRLHLGTPRFLTRCVQAEPHGWQRYWGQVVIPSYPVPCSTFLWVREDAPGTVGHEKMKEAVAQLALMMLGH", "length": 347, "header": "tr|A0A8V0YFK6-1|A0A8V0YFK6_CHICK Isoform 1 of DND microRNA-mediated repression inhibitor 1 OS=Gallus gallus OX=9031 GN=DND1 PE=4 SV=1 CANONICAL=A0A8V0YFK6-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Y754-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFK6/entry#A0A8V0Y754-1", "sequence": { "sequence": "MAEEQWTSSINRTNKMALLAWVRETGIDLVQVNGQRRYGGPPPGWVGSPPPPGSEVYIAKLPRDLYEDTLIPLFQSVGQLYEFRLMLTFSGLNRGFAYAKYSDQHGAGKAIAALNNWEVQEGRAILVCRSFEKCELSVNGLPATLRRRELDTMLLEATEGLLGLTLHASPGRKQGKVAVLTYSSHRAAAMAKKALVEGNVGLFKKKVKVEWLKPELKEQLQACGEKPPPGSVQCLQSPERVLPSSELRGALGRLGALCRRLHLGTPRFLTRCVQAEPHGWQRYWGQVVIPSYPVPCSTFLWVREDAPGTVGHEKMKEAVAQLALMMLGH", "length": 329, "header": "tr|A0A8V0Y754-1|A0A8V0Y754_CHICK Computationally mapped isoform of DND microRNA-mediated repression inhibitor 1 OS=Gallus gallus OX=9031 GN=DND1 PE=4 SV=1 CANONICAL=A0A8V0YFK6-1" }, "locus": { "chromosome": "13", "start_pos": 869803, "end_pos": 867527, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026161.1", "url": "https://www.ensembl.org/id/ENSGALT00010026161.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010014785.1", "url": "https://www.ensembl.org/id/ENSGALP00010014785.1" } ] } }, { "isoform_ac": "A0A8V0YFK6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFK6/entry#A0A8V0YFK6-1", "sequence": { "sequence": "MPVVGQLGALPGPALTSLLPPQQWTSSINRTNKMALLAWVRETGIDLVQVNGQRRYGGPPPGWVGSPPPPGSEVYIAKLPRDLYEDTLIPLFQSVGQLYEFRLMLTFSGLNRGFAYAKYSDQHGAGKAIAALNNWEVQEGRAILVCRSFEKCELSVNGLPATLRRRELDTMLLEATEGLLGLTLHASPGRKQGKVAVLTYSSHRAAAMAKKALVEGNVGLFKKKVKVEWLKPELKEQLQACGEKPPPGSVQCLQSPERVLPSSELRGALGRLGALCRRLHLGTPRFLTRCVQAEPHGWQRYWGQVVIPSYPVPCSTFLWVREDAPGTVGHEKMKEAVAQLALMMLGH", "length": 347, "header": "tr|A0A8V0YFK6-1|A0A8V0YFK6_CHICK Isoform 1 of DND microRNA-mediated repression inhibitor 1 OS=Gallus gallus OX=9031 GN=DND1 PE=4 SV=1 CANONICAL=A0A8V0YFK6-1" }, "locus": { "chromosome": "13", "start_pos": 868856, "end_pos": 867527, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026158.1", "url": "https://www.ensembl.org/id/ENSGALT00010026158.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010014782.1", "url": "https://www.ensembl.org/id/ENSGALP00010014782.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "negative regulation of miRNA-mediated gene silencing", "id": "GO:0060965", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060965", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFK6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFK6" } ], "pmid": "" }, { "name": "mRNA stabilization", "id": "GO:0048255", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048255", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFK6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFK6" } ], "pmid": "" }, { "name": "3'-UTR-mediated mRNA destabilization", "id": "GO:0061158", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061158", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFK6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFK6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFK6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFK6" } ], "pmid": "" }, { "name": "mRNA 3'-UTR binding", "id": "GO:0003730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003730", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFK6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFK6" } ], "pmid": "" }, { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFK6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFK6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFK6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFK6" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFK6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFK6" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFK6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFK6" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFK6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFK6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 29, "end_pos": 31, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YFK6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFK6" }, { "id": "PS50102", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50102" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RRM", "eco_id": "ECO_0000259", "start_pos": 72, "end_pos": 150, "start_aa": "Ser", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 29, "end_pos": 31 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YFL1-1", "uniprot_ac": "A0A8V0YFL1", "uniprot_id": "A0A8V0YFL1_CHICK", "mass": { "chemical_mass": 57095.0, "monoisotopic_mass": 57095.0 }, "refseq": { "ac": "XP_015140062", "name": "cyclin-dependent kinase 19 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015140062" }, "gene_names": [ { "name": "CDK19", "type": "recommended", "evidence": [ { "id": "A0A8V0YFL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFL1" } ] }, { "name": "CDK19", "type": "synonym", "evidence": [ { "id": "XP_015140062", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015140062" } ] } ], "protein_names": [ { "name": "cyclin-dependent kinase", "type": "recommended", "evidence": [ { "id": "A0A8V0YFL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFL1/entry#names_and_taxonomy" } ] }, { "name": "2.7.11.22", "type": "synonym", "evidence": [ { "id": "A0A8V0YFL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFL1/entry#names_and_taxonomy" } ] }, { "name": "cyclin-dependent kinase 19 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015140062", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015140062" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052534.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015140062", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015140062" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFL1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFL1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CDK19", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFL1", "locus": { "chromosome": "3", "start_pos": 66181442, "end_pos": 66067216, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013842", "url": "https://www.ensembl.org/id/ENSGALG00010013842" } ] } } ], "crossref": [ { "id": "A0A8V0YFL1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YFL1", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd07867", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07867", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "421756", "url": "https://www.ncbi.nlm.nih.gov/gene/421756", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000719", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000719", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008271", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008271", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011009", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011009", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017441", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017441", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050108", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050108", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:421756", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:421756", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YFL1", "url": "https://www.orthodb.org/?gene=A0A8V0YFL1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YTT0", "url": "https://www.orthodb.org/?gene=A0A8V0YTT0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24056", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24056", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24056:SF570", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24056:SF570", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00069", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00069", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015140062", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015140062", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "17989", "url": "https://www.rhea-db.org/rhea/17989", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "46608", "url": "https://www.rhea-db.org/rhea/46608", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YFL1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFL1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YFL1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFL1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YTT0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTT0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YTT0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTT0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDYEFKSKLAAERERVEDLFEYEGCKVGRGTYGHVYKARRKDGKDEKEYALKQIEGTGISMSACREIALLRELKHPNVIALQKVFLSHSDRKVWLLFDYAEHDLWHIIKFHRASKANKKPMQLPRSMVKSLLYQILDGIHYLHANWVLHRDLKPANILVMGEGPERGRVKIADMGFARLFNSPLKPLADLDPVVVTFWYRAPELLLGARHYTKAIDIWAIGCIFAELLTSEPIFHCRQEDIKTSNPFHHDQLDRIFSVMGFPADKDWEDIRKMPEYPTLQKDFRRTTYANSSLIKYMEKHKVKPDSKVFLLLQKLLTMDPTKRITSEQALQDPYFQEDPLPTSDVFAGCQIPYPKREFLNEDEPEEKGDKNQQQQNQHQQQTAPQQQPQAAPQQPQQQQQNSTQTNGTAGGTGAGGGGAGGGLQHSQDSSLNQVPPNKKPRIGPSGANSGGPVMPSDYQHSSSRLSYQSNIQGSSQSQSTMGYSTSSQQSSQYHQSHQSHRY", "length": 502, "header": "tr|A0A8V0YFL1-1|A0A8V0YFL1_CHICK Isoform 1 of cyclin-dependent kinase OS=Gallus gallus OX=9031 GN=CDK19 PE=3 SV=1 CANONICAL=A0A8V0YFL1-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YFL1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFL1/entry#A0A8V0YFL1-1", "sequence": { "sequence": "MDYEFKSKLAAERERVEDLFEYEGCKVGRGTYGHVYKARRKDGKDEKEYALKQIEGTGISMSACREIALLRELKHPNVIALQKVFLSHSDRKVWLLFDYAEHDLWHIIKFHRASKANKKPMQLPRSMVKSLLYQILDGIHYLHANWVLHRDLKPANILVMGEGPERGRVKIADMGFARLFNSPLKPLADLDPVVVTFWYRAPELLLGARHYTKAIDIWAIGCIFAELLTSEPIFHCRQEDIKTSNPFHHDQLDRIFSVMGFPADKDWEDIRKMPEYPTLQKDFRRTTYANSSLIKYMEKHKVKPDSKVFLLLQKLLTMDPTKRITSEQALQDPYFQEDPLPTSDVFAGCQIPYPKREFLNEDEPEEKGDKNQQQQNQHQQQTAPQQQPQAAPQQPQQQQQNSTQTNGTAGGTGAGGGGAGGGLQHSQDSSLNQVPPNKKPRIGPSGANSGGPVMPSDYQHSSSRLSYQSNIQGSSQSQSTMGYSTSSQQSSQYHQSHQSHRY", "length": 502, "header": "tr|A0A8V0YFL1-1|A0A8V0YFL1_CHICK Isoform 1 of cyclin-dependent kinase OS=Gallus gallus OX=9031 GN=CDK19 PE=3 SV=1 CANONICAL=A0A8V0YFL1-1" }, "locus": { "chromosome": "3", "start_pos": 66180838, "end_pos": 66067433, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033218.1", "url": "https://www.ensembl.org/id/ENSGALT00010033218.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019627.1", "url": "https://www.ensembl.org/id/ENSGALP00010019627.1" } ] } }, { "isoform_ac": "A0A8V0YTT0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFL1/entry#A0A8V0YTT0-1", "sequence": { "sequence": "MDYEFKSKLAAERERVEDLFEYEGCKVGRGTYGHVYKARRKDGKDEKEYALKQIEGTGISMSACREIALLRELKHPNVIALQKVFLSHSDRKVWLLFDYAEHDLWKPANILVMGEGPERGRVKIADMGFARLFNSPLKPLADLDPVVVTFWYRAPELLLGARHYTKAIDIWAIGCIFAELLTSEPIFHCRQEDIKTSNPFHHDQLDRIFSVMGFPADKDWEDIRKMPEYPTLQKDFRRTTYANSSLIKYMEKHKVKPDSKVFLLLQKLLTMDPTKRITSEQALQDPYFQEDPLPTSDVFAGCQIPYPKREFLNEDEPEEKGDKNQQQQNQHQQQTAPQQQPQAAPQQPQQQQQNSTQTNGTAGGTGAGGGGAGGGLQHSQDSSLNQVPPNKKPRIGPSGANSGGPVMPSDYQHSSSRLSYQSNIQGSSQSQSTMGYSTSSQQSSQYHQSHQSHRY", "length": 455, "header": "tr|A0A8V0YTT0-1|A0A8V0YTT0_CHICK Computationally mapped isoform of cyclin-dependent kinase OS=Gallus gallus OX=9031 GN=CDK19 PE=3 SV=1 CANONICAL=A0A8V0YFL1-1" }, "locus": { "chromosome": "3", "start_pos": 66180838, "end_pos": 66067433, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033222.1", "url": "https://www.ensembl.org/id/ENSGALT00010033222.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019628.1", "url": "https://www.ensembl.org/id/ENSGALP00010019628.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "gga:421756", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:421756", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFL1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFL1" } ], "pmid": "" }, { "name": "cyclin-dependent protein serine/threonine kinase activity", "id": "GO:0004693", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004693", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFL1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFL1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFL1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFL1" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFL1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFL1" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFL1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFL1" } ], "pmid": "" }, { "name": "CKM complex", "id": "GO:1990508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990508", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFL1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFL1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 290, "end_pos": 292, "annotation": "n_glycosylation_sequon" }, { "start_pos": 401, "end_pos": 403, "annotation": "n_glycosylation_sequon" }, { "start_pos": 406, "end_pos": 408, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "17989", "name": "", "equation": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q6U1I9-1", "A0A8V0XNJ2-1", "A0A8V0ZUL0-1", "A0A8V0ZT63-1", "A0A8V1ACW2-1", "A0A8V0Z1X0-1", "A0A8V0YHN2-1", "A0A8V0YMN5-1", "A0A8V0Z807-1", "A0A8V0Z930-1", "A0A8V0YFR6-1", "A0A1D5P0M9-1", "A0A8V0ZBN6-1", "A0A3Q2U9U9-1", "A0A8V0YXZ5-1", "A0A8V0ZSP4-1", "A0A8V0ZXQ9-1", "A0A8V0ZZV3-1", "A0A8V1ADF0-1", "A0A8V0ZFT3-1", "A0A8V0ZA45-1", "A0A8V0ZB33-1", "A0A8V0ZD70-1", "A0A8V0Z8T4-1", "R4GIN8-1", "A0A8V0ZK64-1", "A0A8V0ZC16-1", "A0A8V0ZWW1-1", "E1BY69-1", "A0A8V0ZDW9-1", "A0A8V0ZKA2-1", "A0A3Q3B2F1-1", "F1P356-1", "A0A8V1AHA8-1", "Q8QFP8-1", "F1P011-1", "A0A8V0YKK3-1", "A0A1D5NWT4-1", "A0A1D5PMQ7-1", "E1BWA3-1", "F1NVF2-1", "A0A1D5PXN4-1", "A0A3Q2TY19-1", "A0A3Q2U592-1", "A0A8V0XCV5-1", "A0A1D5P8A9-1", "A0A1D5PMG2-1", "A0A8V0X1Q7-1", "A0A8V0Y935-1", "A0A8V0YM96-1", "A0A8V0YF83-1", "A0A8V0YJP9-1", "A0A8V1AKW4-1", "A0A8V0ZSB4-1", "F1NBT0-1", "P18652-1", "P21868-1", "P21869-1", "P53666-1", "P79996-1", "Q5F3W3-1", "Q5ZJS0-1", "Q5ZKN1-1", "Q5ZLL1-1", "A0A8V0XCS0-1", "A0A8V0XNK8-1", "A0A8V0XLV6-1", "A0A8V0XDR5-1", "E1BYH2-1", "E1BQN6-1", "A0A8V0XU71-1", "Q5ZJH6-1", "A0A8V0Y3D1-1", "A0A8V0Y7C3-1", "A0A8V0YCY4-1", "A0A8V0YIV6-1", "A0A8V0YK18-1", "A0A8V0YM22-1", "A0A8V0YTN5-1", "A0A8V0YTP2-1", "Q5F3L1-1", "A0A8V0Y3L2-1", "A0A8V0YCY8-1", "A0A8V0Y9Q1-1", "A0A8V0ZD48-1", "A0A8V0ZD60-1", "A0A8V0ZBZ2-1", "A0A8V0Z9J0-1", 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"A0A8V1A675-1", "A0A8V1A1P3-1", "A0A8V1ADT4-1", "E1BWT0-1", "A0A8V1ACF6-1", "A0A8V1ADN9-1", "A0A8V1AM12-1", "A0A8V1A4Q4-1", "Q90891-1", "A0A1D5P517-1", "F1NB57-1", "F1NUX4-1", "A0A8V0ZZE4-1", "P05625-1", "P13863-1", "P67962-1", "Q04982-2", "Q0GGW5-1", "Q6XUX0-1", "Q8QGX4-1", "Q9I9E0-1", "Q9IA88-1", "Q5ZJK4-1", "A0A1D5PTJ8-1", "E1C2I2-1", "F1NCX7-1", "F1NKW3-1", "A0A8V1A0W4-1", "A0A8V1A4J8-1", "A0A8V1ACK0-1", "F1NCY7-1", "A0A8V0X6T4-1", "A0A8V0ZFM2-1", "A0A8V0XUM6-1", "A0A8V0XEA3-1", "A0A8V1AIY7-1", "A0A8V0YHH2-1", "A0A3Q2UI52-1", "A0A8V0ZZK5-1", "A0A8V0ZPX2-1", "A0A8V1ACB5-1", "A0A8V0YDH4-1", "A0A8V1AFS4-1", "A0A8V1AH12-1", "A0A8V0YRC9-1", "A0A8V0ZQT5-1", "A0A8V0ZFP1-1", "E1C764-1", "A0A1D5PUY5-1", "F1P4G3-1", "A0A8V0ZMK1-1", "A0A8V0Y2I5-1", "A0A8V0ZLU3-1", "A0A8V0ZNP7-1", "A0A8V0Z2Z3-1", "A0A8V0YNI5-1", "Q90771-1", "A0A8V0X4P0-1", "A0A8V0X7R2-1", "A0A3Q3A664-1", "A0A8V0YGW2-1", "E1C581-1", "A0A8V1AC40-1", "A0A3Q2TUS7-1", "A0A1D5PA08-1", "A0A8V0XFW1-1", "A0A8V0XAH9-1", "A0A8V1A4A1-1", "A0A8V0ZD40-1", "A0A8V0Z6T1-1", "A0A8V1A4V7-1", "E1C093-1", "A0A8V0YZF2-1", "E1BX69-1", "A0A8V0XI18-1", "A0A8V0Y955-1", "A0A1D5PB73-1", "A0A1D5PV76-1", "A0A1D5PX90-1", "A0A1L1RWI9-1", "A0A3Q2TV19-1", "A0A3Q2UF44-1", "A0A8V0X4Q3-1", "A0A8V0Z124-1", "A0A8V0Z6K4-1", "A0A8V1AE45-1", "A0A8V0YZV9-1", "A0A8V0YYZ3-1", "A0A8V0ZUC6-1", "A0A8V0ZUU8-1", "A0A8V1AG70-1", "F1NA68-1", "F1NLR7-1", "A0A8V0Y6K1-1", "A0A8V0XS42-1", "A0A8V0YRN4-1", "A0A8V0YFP8-1", "A0A8V1A7P9-1", "A0A1D5PRN8-1", "A0A3Q3AAD7-1", "A0A3Q2TWZ8-1", "A0A8V0XBZ0-1", "A0A8V0XFX2-1", "A0A8V0YFL1-1", "A0A8V0YTL9-1", "A0A8V0YMB3-1", "A0A8V0X2Y2-1", "A0A8V0XCY6-1", "A0A3Q2UI62-1", "A0A8V0Y241-1", "A0A8V0Z8G2-1", "A0A8V1ABR8-1", "A0A8V1AP60-1", "A0A8V0YZM1-1", "A0A8V0ZB38-1", "A0A8V0Z466-1", "A0A8V0ZA06-1", "A0A8V1AMQ2-1", "A0A8V0ZGY3-1", "A0A8V0ZQJ2-1", "A0A8V0ZYU6-1", "A0A8V1A513-1", "A0A8V0XE48-1", "A0A8V0XQQ4-1", "A0A8V0XKG0-1" ], "evidence": [ { "id": "17989", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/17989" } ] }, { "id": "46608", "name": "", "equation": "L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A1D5PUY5-1", "Q6U1I9-1", "A0A8V0XNJ2-1", "A0A8V0ZUL0-1", "A0A8V0ZT63-1", "A0A8V1ACW2-1", "A0A8V0Z1X0-1", "A0A8V0YHN2-1", "A0A8V0YMN5-1", "A0A8V0Z807-1", "A0A8V0Z930-1", "A0A8V0YFR6-1", "A0A1D5P0M9-1", "A0A8V0ZBN6-1", "A0A3Q2U9U9-1", "A0A8V0YRC9-1", "A0A8V0YXZ5-1", "A0A8V0ZSP4-1", "A0A8V0ZXQ9-1", "A0A8V0ZZV3-1", "A0A8V1ADF0-1", "A0A8V0ZFT3-1", "A0A8V0ZA45-1", "A0A8V0ZB33-1", "A0A8V0ZD70-1", "A0A8V0Z8T4-1", "R4GIN8-1", "A0A8V0ZK64-1", "A0A8V0ZC16-1", "A0A8V0ZWW1-1", "E1BY69-1", "A0A8V0ZDW9-1", "A0A8V0ZKA2-1", "A0A3Q3B2F1-1", "F1P356-1", "A0A8V1AHA8-1", "Q8QFP8-1", "F1P011-1", "A0A8V0YKK3-1", "A0A1D5NWT4-1", "A0A1D5PMQ7-1", "E1BWA3-1", "F1NVF2-1", "A0A1D5PXN4-1", "A0A3Q2TY19-1", "A0A3Q2U592-1", "A0A8V0XCV5-1", "A0A1D5P8A9-1", "A0A1D5PMG2-1", "A0A8V0X1Q7-1", "A0A8V0Y935-1", "A0A8V0YM96-1", "A0A8V0YF83-1", "A0A8V0YJP9-1", "A0A8V1AKW4-1", "A0A1D5P517-1", "A0A8V0ZSB4-1", "F1NBT0-1", "P18652-1", "P21868-1", "P21869-1", "P53666-1", "P79996-1", "Q5F3W3-1", "Q5ZJS0-1", "Q5ZKN1-1", "Q5ZLL1-1", "A0A8V0XCS0-1", "A0A8V0XNK8-1", "A0A8V0XLV6-1", "A0A8V0XDR5-1", "E1BYH2-1", "F1NB57-1", "E1BQN6-1", "A0A8V0XU71-1", "Q5ZJH6-1", "A0A8V0Y3D1-1", "A0A8V0Y7C3-1", "A0A8V0YCY4-1", "A0A8V0YIV6-1", "A0A8V0YK18-1", "A0A8V0YM22-1", "A0A8V0YTN5-1", "A0A8V0YTP2-1", "Q5F3L1-1", "A0A8V0XU96-1", "E1C6T4-1", "A0A8V0Y3L2-1", "A0A8V0YCY8-1", "A0A8V0Y9Q1-1", "A0A8V0ZD48-1", "A0A8V0ZD60-1", "A0A8V0ZBZ2-1", "A0A8V0Z9J0-1", "A0A8V1ABF3-1", "Q8AYC9-1", "A0A8V0Z927-1", "A0A8V1A2T9-1", "Q5ZKI0-1", "Q7T0B1-1", "P10741-1", "A0A8V1AMK5-1", "P67962-1", "A0A8V0YFH4-1", "E1C848-1", "A0A8V0X8M1-1", "E1BW33-1", "A0A8V0Z283-1", "A0A8V0Z157-1", "A0A3Q2U4X3-1", "A0A8V0XW11-1", "E1BUG0-1", "A0A8V1ABP4-1", "A0A8V1AJA4-1", "A0A8V1AEH4-1", "F1NJH1-1", "A0A3Q2TRY2-1", 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"E1C2I2-1", "F1NCX7-1", "F1NKW3-1", "A0A8V1A0W4-1", "A0A8V1A4J8-1", "A0A8V1ACK0-1", "F1NCY7-1", "A0A8V0X6T4-1", "A0A8V0XUM6-1", "A0A8V0XEA3-1", "A0A8V0YHH2-1", "A0A3Q2UI52-1", "A0A8V0ZZK5-1", "A0A8V0ZPX2-1", "A0A8V1ACB5-1", "A0A8V0YDH4-1", "A0A8V1AFS4-1", "A0A8V1AH12-1", "A0A8V0ZQT5-1", "A0A8V0ZFP1-1", "E1C764-1", "F1P4G3-1", "A0A8V0Y2I5-1", "A0A8V0ZLU3-1", "A0A8V0ZNP7-1", "A0A8V0Z2Z3-1", "A0A8V0YNI5-1", "Q90771-1", "A0A8V0X4P0-1", "A0A8V0X7R2-1", "A0A3Q3A664-1", "A0A8V0YGW2-1", "E1C581-1", "A0A8V1AC40-1", "A0A3Q2TUS7-1", "A0A1D5PA08-1", "A0A8V0XFW1-1", "A0A8V0XAH9-1", "A0A8V0ZFM2-1", "A0A8V1A4A1-1", "A0A8V0ZD40-1", "A0A8V0Z6T1-1", "A0A8V1A4V7-1", "A0A8V0YZF2-1", "E1BX69-1", "A0A8V0Y955-1", "A0A1D5PB73-1", "A0A1D5PV76-1", "A0A1D5PX90-1", "A0A1L1RWI9-1", "A0A3Q2TV19-1", "A0A3Q2UF44-1", "A0A8V0X4Q3-1", "A0A8V0Z124-1", "A0A8V0Z6K4-1", "A0A8V1AIY7-1", "A0A8V1AE45-1", "A0A8V0YZV9-1", "A0A8V0YYZ3-1", "A0A8V0ZUC6-1", "A0A8V0ZUU8-1", "A0A8V1AG70-1", "F1NA68-1", "F1NLR7-1", "A0A8V0Y6K1-1", "A0A8V0XS42-1", "A0A8V0YRN4-1", "A0A8V0YFP8-1", "A0A8V1A7P9-1", "A0A1D5PRN8-1", "A0A3Q3AAD7-1", "A0A3Q2TWZ8-1", "A0A8V0XBZ0-1", "A0A8V0XFX2-1", "A0A8V0YFL1-1", "A0A8V0YTL9-1", "A0A8V0YMB3-1", "A0A8V0X2Y2-1", "A0A8V0XCY6-1", "A0A3Q2UI62-1", "A0A8V0Y241-1", "A0A8V0Z8G2-1", "A0A8V1ABR8-1", "A0A8V1AP60-1", "A0A8V0YZM1-1", "A0A8V0ZB38-1", "A0A8V0Z466-1", "A0A8V0ZA06-1", "A0A8V1AMQ2-1", "A0A8V0ZGY3-1", "A0A8V0ZQJ2-1", "A0A8V0ZYU6-1", "A0A8V1A513-1", "A0A8V0XE48-1", "A0A8V0XKG0-1" ], "evidence": [ { "id": "46608", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/46608" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A1D5NWT4", "gene_name": "RPS6KA3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5NWT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NWT4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { 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"https://www.uniprot.org/uniprotkb/A0A8V0XG21" } ] } ] }, { "uniprot_ac": "A0A8V0XI18", "gene_name": "ATM", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XI18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XI18" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XI18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XI18" } ] } ] }, { "uniprot_ac": "A0A8V0XKG0", "gene_name": "NEK9", "activity": [ { "ec_number": "2.7.11.38", "activity": "L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XKG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XKG0" } ] }, { "ec_number": "2.7.11.38", "activity": "", "evidence": [ { "id": "A0A8V0XKG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XKG0" } ] } ] }, { "uniprot_ac": "A0A8V0XLV6", "gene_name": "MAPK10", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XLV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XLV6" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0XLV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XLV6" } ] } ] }, { "uniprot_ac": "A0A8V0XMT1", "gene_name": "MOS", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XMT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMT1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XMT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMT1" } ] } ] }, { "uniprot_ac": "A0A8V0XMX8", "gene_name": "MASTL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XMX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMX8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XMX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMX8" } ] } ] }, { "uniprot_ac": "A0A8V0XND6", "gene_name": "RIOK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XND6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XND6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XND6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XND6" } ] } ] }, { "uniprot_ac": "A0A8V0XNJ2", "gene_name": "CDK8", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XNJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNJ2" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XNJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNJ2" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0XNJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNJ2" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A8V0XNJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNJ2" } ] } ] }, { "uniprot_ac": "A0A8V0XNK8", "gene_name": "PRKCQ", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XNK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNK8" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V0XNK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNK8" } ] } ] }, { "uniprot_ac": "A0A8V0XQ14", "gene_name": "PLK4", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XQ14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ14" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0A8V0XQ14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ14" } ] } ] }, { "uniprot_ac": "A0A8V0XQ97", "gene_name": "CDK14", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XQ97", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ97" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0XQ97", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ97" } ] } ] }, { "uniprot_ac": "A0A8V0XQQ4", "gene_name": "NME7", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQQ4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQQ4" } ] } ] }, { "uniprot_ac": "A0A8V0XQS0", "gene_name": "STK24", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XQS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQS0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XQS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQS0" } ] } ] }, { "uniprot_ac": "A0A8V0XS42", "gene_name": "MAP3K4", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XS42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XS42" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0XS42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XS42" } ] } ] }, { "uniprot_ac": "A0A8V0XU71", "gene_name": "MYO3A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XU71", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XU71" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XU71", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XU71" } ] } ] }, { "uniprot_ac": "A0A8V0XU96", "gene_name": "PRKD1", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XU96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XU96" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V0XU96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XU96" } ] } ] }, { "uniprot_ac": "A0A8V0XUM6", "gene_name": "LATS1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XUM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XUM6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XUM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XUM6" } ] } ] }, { "uniprot_ac": "A0A8V0XW11", "gene_name": "RPS6KA2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XW11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XW11" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XW11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XW11" } ] } ] }, { "uniprot_ac": "A0A8V0XW29", "gene_name": "CDKL2", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XW29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XW29" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0XW29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XW29" } ] } ] }, { "uniprot_ac": "A0A8V0XXB8", "gene_name": "MAPK15", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XXB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XXB8" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0XXB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XXB8" } ] } ] }, { "uniprot_ac": "A0A8V0Y074", "gene_name": "NEK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y074", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y074" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y074", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y074" } ] } ] }, { "uniprot_ac": "A0A8V0Y241", "gene_name": "LOC426385", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y241", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y241" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y241", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y241" } ] } ] }, { "uniprot_ac": "A0A8V0Y2I5", "gene_name": "CDK7", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] }, { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] } ] }, { "uniprot_ac": "A0A8V0Y3D1", "gene_name": "LRRK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y3D1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y3D1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": 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"https://www.uniprot.org/uniprotkb/A0A8V0Y457" } ] } ] }, { "uniprot_ac": "A0A8V0Y4L8", "gene_name": "HUNK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y4L8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y4L8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y4L8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y4L8" } ] } ] }, { "uniprot_ac": "A0A8V0Y6K1", "gene_name": "MAK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y6K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y6K1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y6K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y6K1" } ] } ] }, { 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"ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y8X9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y8X9" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "A0A8V0Y8X9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y8X9" } ] } ] }, { "uniprot_ac": "A0A8V0Y935", "gene_name": "MAST4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y935", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y935" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y935", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y935" } ] } ] }, { "uniprot_ac": "A0A8V0Y955", "gene_name": "PAK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y955", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y955" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y955", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y955" } ] } ] }, { "uniprot_ac": "A0A8V0Y9Q1", "gene_name": "LOC107055388", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y9Q1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9Q1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y9Q1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9Q1" } ] } ] }, { "uniprot_ac": "A0A8V0YCV9", "gene_name": "SIK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YCV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCV9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YCV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCV9" } ] } ] }, { "uniprot_ac": "A0A8V0YCY4", "gene_name": "AURKB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YCY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCY4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YCY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCY4" } ] } ] }, { "uniprot_ac": "A0A8V0YCY8", "gene_name": "RIOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YCY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCY8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YCY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCY8" } ] } ] }, { "uniprot_ac": "A0A8V0YDH4", "gene_name": "ALPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YDH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDH4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YDH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDH4" } ] } ] }, { "uniprot_ac": "A0A8V0YF83", "gene_name": "WNK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YF83", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF83" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YF83", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF83" } ] } ] }, { "uniprot_ac": "A0A8V0YFH4", "gene_name": "NRK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YFH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFH4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YFH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFH4" } ] } ] }, { "uniprot_ac": "A0A8V0YFL1", "gene_name": "CDK19", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YFL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFL1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0YFL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFL1" } ] } ] }, { "uniprot_ac": "A0A8V0YFP8", "gene_name": "RIPK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YFP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFP8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YFP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFP8" } ] } ] }, { "uniprot_ac": "A0A8V0YFR6", "gene_name": "TNIK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YFR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFR6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YFR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFR6" } ] } ] }, { "uniprot_ac": "A0A8V0YGW2", "gene_name": "STK32B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YGW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGW2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YGW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGW2" } ] } ] }, { "uniprot_ac": "A0A8V0YHH2", "gene_name": "STK38L", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YHH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHH2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YHH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHH2" } ] } ] }, { "uniprot_ac": "A0A8V0YHN2", "gene_name": "RPS6KA1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YHN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHN2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YHN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHN2" } ] } ] }, { "uniprot_ac": "A0A8V0YIV6", "gene_name": "DYRK1A", "activity": [ { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] }, { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] } ] }, { "uniprot_ac": "A0A8V0YJP9", "gene_name": "RIOK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YJP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJP9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YJP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJP9" } ] } ] }, { "uniprot_ac": "A0A8V0YK18", "gene_name": "CDC42BPB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YK18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK18" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YK18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK18" } ] } ] }, { "uniprot_ac": "A0A8V0YKK3", "gene_name": "MAP4K4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YKK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKK3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YKK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKK3" } ] } ] }, { "uniprot_ac": "A0A8V0YLV1", "gene_name": "MARK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": 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"ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YMN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMN5" } ] } ] }, { "uniprot_ac": "A0A8V0YNI5", "gene_name": "NIM1K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YNI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNI5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YNI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNI5" } ] } ] }, { "uniprot_ac": "A0A8V0YRC9", "gene_name": "TNK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YRC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRC9" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YRC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRC9" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0YRC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRC9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YRC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRC9" } ] } ] }, { "uniprot_ac": "A0A8V0YRN4", "gene_name": "GAK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YRN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRN4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YRN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRN4" } ] } ] }, { "uniprot_ac": "A0A8V0YSH3", "gene_name": "RPS6KA6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YSH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSH3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YSH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSH3" } ] } ] }, { "uniprot_ac": "A0A8V0YTI1", "gene_name": "TSSK6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTI1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTI1" } ] } ] }, { "uniprot_ac": "A0A8V0YTL9", "gene_name": "VRK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTL9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTL9" } ] } ] }, { "uniprot_ac": "A0A8V0YTN5", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTN5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTN5" } ] } ] }, { "uniprot_ac": "A0A8V0YTP2", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTP2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTP2" } ] } ] }, { "uniprot_ac": "A0A8V0YXZ5", "gene_name": "CDC42BPA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YXZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXZ5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YXZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXZ5" } ] } ] }, { "uniprot_ac": "A0A8V0YYX2", "gene_name": "PAK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YYX2", "database": 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"https://www.uniprot.org/uniprotkb/A0A8V0YZ74" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V0YZ74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZ74" } ] } ] }, { "uniprot_ac": "A0A8V0YZF2", "gene_name": "PAK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZF2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YZF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZF2" } ] } ] }, { "uniprot_ac": "A0A8V0YZK0", "gene_name": "MAP3K6", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZK0" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0YZK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZK0" } ] } ] }, { "uniprot_ac": "A0A8V0YZM1", "gene_name": "MOK", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZM1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0YZM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZM1" } ] }, { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZM1" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0YZM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZM1" } ] } ] }, { "uniprot_ac": "A0A8V0YZV9", "gene_name": "ATR", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZV9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YZV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZV9" } ] } ] }, { "uniprot_ac": "A0A8V0YZY4", "gene_name": "SBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZY4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YZY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZY4" } ] } ] }, { "uniprot_ac": "A0A8V0Z124", "gene_name": "VRK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z124", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z124" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z124", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z124" } ] } ] }, { "uniprot_ac": "A0A8V0Z157", "gene_name": "MARK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z157", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z157" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z157", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z157" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A8V0Z157", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z157" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z157", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z157" } ] } ] }, { "uniprot_ac": "A0A8V0Z1X0", "gene_name": "MAP4K3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z1X0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1X0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z1X0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1X0" } ] } ] }, { "uniprot_ac": "A0A8V0Z283", "gene_name": "MARK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z283", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z283" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z283", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z283" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A8V0Z283", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z283" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z283", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z283" } ] } ] }, { "uniprot_ac": "A0A8V0Z2E3", "gene_name": "PDIK1L", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z2E3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2E3" } ] }, { "ec_number": 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"database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z466" } ] } ] }, { "uniprot_ac": "A0A8V0Z6K4", "gene_name": "PIK3R4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z6K4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6K4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z6K4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6K4" } ] } ] }, { "uniprot_ac": "A0A8V0Z6T1", "gene_name": "ERN2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z6T1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6T1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z6T1", "database": "UniProtKB", "url": 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{ "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z930", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z930" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V0Z930", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z930" } ] } ] }, { "uniprot_ac": "A0A8V0Z9J0", "gene_name": "CIT", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z9J0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9J0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z9J0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9J0" } ] } ] }, { "uniprot_ac": "A0A8V0ZA06", "gene_name": "CDKL1", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZA06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA06" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0ZA06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA06" } ] } ] }, { "uniprot_ac": "A0A8V0ZA45", "gene_name": "MAP4K5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZA45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA45" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZA45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA45" } ] } ] }, { "uniprot_ac": "A0A8V0ZB33", "gene_name": "CAMK2G", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZB33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB33" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V0ZB33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB33" } ] } ] }, { "uniprot_ac": "A0A8V0ZB38", "gene_name": "CIITA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZB38", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB38" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZB38", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB38" } ] } ] }, { "uniprot_ac": "A0A8V0ZBN6", "gene_name": "MAP2K1", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZBN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBN6" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V0ZBN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBN6" } ] } ] }, { "uniprot_ac": "A0A8V0ZBZ2", "gene_name": "MAP3K9", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZBZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBZ2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0ZBZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBZ2" } ] } ] }, { "uniprot_ac": "A0A8V0ZC16", "gene_name": "KALRN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZC16", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC16" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZC16", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC16" } ] } ] }, { "uniprot_ac": "A0A8V0ZD40", "gene_name": "CDC2L1", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD40" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD40" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A8V0ZD40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD40" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0ZD40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD40" } ] } ] }, { "uniprot_ac": "A0A8V0ZD48", "gene_name": "PRKCE", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD48" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V0ZD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD48" } ] } ] }, { "uniprot_ac": "A0A8V0ZD60", "gene_name": "STK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD60" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZD60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD60" } ] } ] }, { "uniprot_ac": "A0A8V0ZD70", "gene_name": "DCLK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD70" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZD70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD70" } ] } ] }, { "uniprot_ac": "A0A8V0ZDW9", "gene_name": "NEK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZDW9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDW9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZDW9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDW9" } ] } ] }, { "uniprot_ac": "A0A8V0ZFM2", "gene_name": "LMTK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZFM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFM2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZFM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFM2" } ] } ] }, { "uniprot_ac": "A0A8V0ZFP1", "gene_name": "TTBK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZFP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFP1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZFP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFP1" } ] } ] }, { "uniprot_ac": "A0A8V0ZFT3", "gene_name": "LRRK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZFT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFT3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZFT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFT3" } ] } ] }, { "uniprot_ac": "A0A8V0ZGY3", "gene_name": "HIPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZGY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGY3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZGY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGY3" } ] } ] }, { "uniprot_ac": "A0A8V0ZH91", "gene_name": "WNK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZH91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH91" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZH91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH91" } ] } ] }, { "uniprot_ac": "A0A8V0ZI32", "gene_name": "STK16", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZI32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI32" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZI32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI32" } ] } ] }, { "uniprot_ac": "A0A8V0ZK64", "gene_name": "PDPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZK64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK64" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZK64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK64" } ] } ] }, { "uniprot_ac": "A0A8V0ZKA2", "gene_name": "EIF2AK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZKA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKA2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZKA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKA2" } ] } ] }, { "uniprot_ac": "A0A8V0ZKM9", "gene_name": "STK36", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZKM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKM9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZKM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKM9" } ] } ] }, { "uniprot_ac": "A0A8V0ZLU3", "gene_name": "TLK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZLU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLU3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZLU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLU3" } ] } ] }, { "uniprot_ac": "A0A8V0ZMK1", "gene_name": "PIKFYVE", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZMK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMK1" } ] }, { "ec_number": "2.7.1.150", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,5-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZMK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMK1" } ] }, { "ec_number": "2.7.1.150", "activity": "", "evidence": [ { "id": "A0A8V0ZMK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMK1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZMK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMK1" } ] } ] }, { "uniprot_ac": "A0A8V0ZNP7", "gene_name": "SGK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZNP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNP7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZNP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNP7" } ] } ] }, { "uniprot_ac": "A0A8V0ZPX2", "gene_name": "ALPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZPX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPX2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZPX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPX2" } ] } ] }, { "uniprot_ac": "A0A8V0ZQJ2", "gene_name": "RPS6KB2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZQJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQJ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZQJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQJ2" } ] } ] }, { "uniprot_ac": "A0A8V0ZQT5", "gene_name": "SLC13A3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZQT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQT5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZQT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQT5" } ] } ] }, { "uniprot_ac": "A0A8V0ZRX1", "gene_name": "SETD6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZRX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRX1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZRX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRX1" } ] }, { "ec_number": "2.1.1.-", "activity": "", "evidence": [ { "id": "A0A8V0ZRX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRX1" } ] } ] }, { "uniprot_ac": "A0A8V0ZSB4", "gene_name": "SIK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZSB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSB4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZSB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSB4" } ] } ] }, { "uniprot_ac": "A0A8V0ZSP4", "gene_name": "PKN2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZSP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSP4" } ] }, { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZSP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSP4" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V0ZSP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSP4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZSP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSP4" } ] } ] }, { "uniprot_ac": "A0A8V0ZT63", "gene_name": "STK25", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZT63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT63" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZT63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT63" } ] } ] }, { "uniprot_ac": "A0A8V0ZUC6", "gene_name": "PAK6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZUC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUC6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZUC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUC6" } ] } ] }, { "uniprot_ac": "A0A8V0ZUL0", "gene_name": "PASK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZUL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUL0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZUL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUL0" } ] } ] }, { "uniprot_ac": "A0A8V0ZUU8", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZUU8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUU8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZUU8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUU8" } ] } ] }, { "uniprot_ac": "A0A8V0ZUU9", "gene_name": "MKNK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZUU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUU9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZUU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUU9" } ] } ] }, { "uniprot_ac": "A0A8V0ZWC7", "gene_name": "EIF2AK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZWC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWC7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZWC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWC7" } ] } ] }, { "uniprot_ac": "A0A8V0ZWW1", "gene_name": "MAP3K12", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZWW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWW1" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0ZWW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWW1" } ] } ] }, { "uniprot_ac": "A0A8V0ZXQ9", "gene_name": "PRKG1", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZXQ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXQ9" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "A0A8V0ZXQ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXQ9" } ] } ] }, { "uniprot_ac": "A0A8V0ZYU6", "gene_name": "TNNI3K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZYU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZYU6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZYU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZYU6" } ] } ] }, { "uniprot_ac": "A0A8V0ZZE4", "gene_name": "OBSCN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZZE4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZE4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZZE4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZE4" } ] } ] }, { "uniprot_ac": "A0A8V0ZZK5", "gene_name": "STK38", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZZK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZK5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZZK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZK5" } ] } ] }, { "uniprot_ac": "A0A8V0ZZV3", "gene_name": "MYO3B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZZV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZV3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZZV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZV3" } ] } ] }, { "uniprot_ac": "A0A8V1A069", "gene_name": "TESK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A069", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A069" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V1A069", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A069" } ] } ] }, { "uniprot_ac": "A0A8V1A0W4", "gene_name": "ULK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A0W4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0W4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A0W4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0W4" } ] } ] }, { "uniprot_ac": "A0A8V1A0Y8", "gene_name": "MAST2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A0Y8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0Y8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A0Y8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0Y8" } ] } ] }, { "uniprot_ac": "A0A8V1A1P3", "gene_name": "SRPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A1P3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1P3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A1P3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1P3" } ] } ] }, { "uniprot_ac": "A0A8V1A1Y7", "gene_name": "CDK2", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A1Y7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1Y7" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V1A1Y7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1Y7" } ] } ] }, { "uniprot_ac": "A0A8V1A2T9", "gene_name": "MAP3K14", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A2T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2T9" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V1A2T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2T9" } ] } ] }, { "uniprot_ac": "A0A8V1A3T8", "gene_name": "MAST3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A3T8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3T8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A3T8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3T8" } ] } ] }, { "uniprot_ac": "A0A8V1A4A1", "gene_name": "CAMKK2", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4A1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4A1" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V1A4A1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4A1" } ] } ] }, { "uniprot_ac": "A0A8V1A4J8", "gene_name": "MAPKAPK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4J8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4J8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A4J8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4J8" } ] } ] }, { "uniprot_ac": "A0A8V1A4Q4", "gene_name": "MAPK3", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4Q4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4Q4" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V1A4Q4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4Q4" } ] } ] }, { "uniprot_ac": "A0A8V1A4V7", "gene_name": "HIPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4V7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4V7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A4V7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4V7" } ] } ] }, { "uniprot_ac": "A0A8V1A513", "gene_name": "DAPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A513", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A513" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A513", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A513" } ] } ] }, { "uniprot_ac": "A0A8V1A675", "gene_name": "CSNK1G2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A675", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A675" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A675", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A675" } ] } ] }, { "uniprot_ac": "A0A8V1A7E0", "gene_name": "DYRK3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7E0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E0" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V1A7E0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E0" } ] } ] }, { "uniprot_ac": "A0A8V1A7E9", "gene_name": "SIK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7E9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A7E9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E9" } ] } ] }, { "uniprot_ac": "A0A8V1A7M0", "gene_name": "STK39", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7M0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7M0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A7M0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7M0" } ] } ] }, { "uniprot_ac": "A0A8V1A7P9", "gene_name": "DCAF1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A7P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P9" } ] } ] }, { "uniprot_ac": "A0A8V1A9S5", "gene_name": "NUAK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A9S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9S5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A9S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9S5" } ] } ] }, { "uniprot_ac": "A0A8V1ABF3", "gene_name": "PRKAA2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] } ] }, { "uniprot_ac": "A0A8V1ABP4", "gene_name": "DSTYK", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABP4" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V1ABP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABP4" } ] } ] }, { "uniprot_ac": "A0A8V1ABR8", "gene_name": "CAMK4L", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABR8" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V1ABR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABR8" } ] } ] }, { "uniprot_ac": "A0A8V1AC40", "gene_name": "CDK18", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AC40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC40" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V1AC40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC40" } ] } ] }, { "uniprot_ac": "A0A8V1ACB5", "gene_name": "MAPK13", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACB5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V1ACB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACB5" } ] } ] }, { "uniprot_ac": "A0A8V1ACF6", "gene_name": "PIM1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACF6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ACF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACF6" } ] } ] }, { "uniprot_ac": "A0A8V1ACK0", "gene_name": "MAPKAPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACK0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ACK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACK0" } ] } ] }, { "uniprot_ac": "A0A8V1ACW2", "gene_name": "WNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACW2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ACW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACW2" } ] } ] }, { "uniprot_ac": "A0A8V1ADF0", "gene_name": "MAP2K2", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ADF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADF0" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V1ADF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADF0" } ] } ] }, { "uniprot_ac": "A0A8V1ADN9", "gene_name": "NLK", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ADN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADN9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V1ADN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADN9" } ] } ] }, { "uniprot_ac": "A0A8V1ADT4", "gene_name": "MKNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ADT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADT4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ADT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADT4" } ] } ] }, { "uniprot_ac": "A0A8V1AE45", "gene_name": "ERN1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AE45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE45" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AE45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE45" } ] } ] }, { "uniprot_ac": "A0A8V1AEH4", "gene_name": "STK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AEH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEH4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AEH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEH4" } ] } ] }, { "uniprot_ac": "A0A8V1AFS4", "gene_name": "STKLD1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AFS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFS4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AFS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFS4" } ] } ] }, { "uniprot_ac": "A0A8V1AG70", "gene_name": "LOC100857512", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AG70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AG70" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AG70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AG70" } ] } ] }, { "uniprot_ac": "A0A8V1AH12", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AH12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH12" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AH12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH12" } ] } ] }, { "uniprot_ac": "A0A8V1AHA8", "gene_name": "NEK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AHA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHA8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AHA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHA8" } ] } ] }, { "uniprot_ac": "A0A8V1AIY7", "gene_name": "AATK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AIY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIY7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AIY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIY7" } ] } ] }, { "uniprot_ac": "A0A8V1AJA4", "gene_name": "RPS6KB1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AJA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJA4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AJA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJA4" } ] } ] }, { "uniprot_ac": "A0A8V1AKW4", "gene_name": "MAP2K4", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AKW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKW4" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V1AKW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKW4" } ] } ] }, { "uniprot_ac": "A0A8V1AM12", "gene_name": "GSG2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AM12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM12" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AM12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM12" } ] } ] }, { "uniprot_ac": "A0A8V1AMK5", "gene_name": "PRKCA", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AMK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMK5" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V1AMK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMK5" } ] } ] }, { "uniprot_ac": "A0A8V1AMQ2", "gene_name": "CAMKK1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AMQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMQ2" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V1AMQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMQ2" } ] } ] }, { "uniprot_ac": "A0A8V1AP60", "gene_name": "KSR1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AP60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP60" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AP60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP60" } ] } ] }, { "uniprot_ac": "E1BQN6", "gene_name": "PRKCZ", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BQN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQN6" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1BQN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQN6" } ] } ] }, { "uniprot_ac": "E1BQV7", "gene_name": "SLK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BQV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQV7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BQV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQV7" } ] } ] }, { "uniprot_ac": "E1BUG0", "gene_name": "CDK12", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] } ] }, { "uniprot_ac": "E1BW33", "gene_name": "SMG1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BW33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BW33" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BW33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BW33" } ] } ] }, { "uniprot_ac": "E1BWA3", "gene_name": "PRKCI", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BWA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWA3" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1BWA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWA3" } ] } ] }, { "uniprot_ac": "E1BWT0", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BWT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWT0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BWT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWT0" } ] } ] }, { "uniprot_ac": "E1BX69", "gene_name": "EIF2AK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BX69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BX69" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BX69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BX69" } ] } ] }, { "uniprot_ac": "E1BY69", "gene_name": "PIM3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BY69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BY69" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BY69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BY69" } ] } ] }, { "uniprot_ac": "E1BYH2", "gene_name": "TAOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BYH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BYH2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BYH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BYH2" } ] } ] }, { "uniprot_ac": "E1C093", "gene_name": "PIK3CG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.154", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.154", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] } ] }, { "uniprot_ac": "E1C2I2", "gene_name": "MASTL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C2I2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C2I2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C2I2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C2I2" } ] } ] }, { "uniprot_ac": "E1C581", "gene_name": "TBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C581", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C581" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C581", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C581" } ] } ] }, { "uniprot_ac": "E1C6T4", "gene_name": "PRKD3", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C6T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C6T4" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1C6T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C6T4" } ] } ] }, { "uniprot_ac": "E1C764", "gene_name": "BMP2K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C764", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C764" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C764", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C764" } ] } ] }, { "uniprot_ac": "E1C848", "gene_name": "MAP3K8", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C848", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C848" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1C848", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C848" } ] } ] }, { "uniprot_ac": "F1NA68", "gene_name": "CDK3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NA68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NA68" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1NA68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NA68" } ] } ] }, { "uniprot_ac": "F1NB57", "gene_name": "PLK2", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NB57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NB57" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "F1NB57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NB57" } ] } ] }, { "uniprot_ac": "F1NBT0", "gene_name": "STK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NBT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NBT0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1NBT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NBT0" } ] } ] }, { "uniprot_ac": "F1NCX7", "gene_name": "PLK1", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NCX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCX7" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "F1NCX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCX7" } ] } ] }, { "uniprot_ac": "F1NCY7", "gene_name": "MAPKAPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NCY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCY7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1NCY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCY7" } ] } ] }, { "uniprot_ac": "F1NJH1", "gene_name": "PRKCH", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NJH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NJH1" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1NJH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NJH1" } ] } ] }, { "uniprot_ac": "F1NKW3", "gene_name": "MAP3K15", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NKW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NKW3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1NKW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NKW3" } ] } ] }, { "uniprot_ac": "F1NLR7", "gene_name": "CLK3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NLR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NLR7" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "F1NLR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NLR7" } ] } ] }, { "uniprot_ac": "F1NUX4", "gene_name": "MTOR", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NUX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NUX4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1NUX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NUX4" } ] } ] }, { "uniprot_ac": "F1NVF2", "gene_name": "MAP2K6", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NVF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NVF2" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "F1NVF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NVF2" } ] } ] }, { "uniprot_ac": "F1P011", "gene_name": "CAMK2A", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1P011", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P011" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "F1P011", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P011" } ] } ] }, { "uniprot_ac": "F1P356", "gene_name": "NUAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1P356", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P356" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1P356", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P356" } ] } ] }, { "uniprot_ac": "F1P4G3", "gene_name": "HIPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1P4G3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P4G3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1P4G3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P4G3" } ] } ] }, { "uniprot_ac": "P05625", "gene_name": "RAF1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P05625", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05625" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P05625", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05625" } ] } ] }, { "uniprot_ac": "P10741", "gene_name": "MOS", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P10741", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P10741" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P10741", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P10741" } ] } ] }, { "uniprot_ac": "P13863", "gene_name": "CDK1", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P13863", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13863" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "P13863", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13863" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "P13863", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13863" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "P13863", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13863" } ] } ] }, { "uniprot_ac": "P18652", "gene_name": "RPS6KA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P18652", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P18652" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P18652", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P18652" } ] } ] }, { "uniprot_ac": "P21868", "gene_name": "CSNK2A1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P21868", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P21868" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P21868", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P21868" } ] } ] }, { "uniprot_ac": "P21869", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P21869", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P21869" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P21869", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P21869" } ] } ] }, { "uniprot_ac": "P53666", "gene_name": "LIMK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P53666", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P53666" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P53666", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P53666" } ] } ] }, { "uniprot_ac": "P67962", "gene_name": "CSNK1A1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P67962", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P67962" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P67962", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P67962" } ] } ] }, { "uniprot_ac": "P79996", "gene_name": "MAPK9", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = 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Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040513307", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040513307" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFL8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFL8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "IL18RAP", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFL8", "locus": { "chromosome": "1", "start_pos": 134051127, "end_pos": 134035672, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013857", "url": "https://www.ensembl.org/id/ENSGALG00010013857" } ] } } ], "crossref": [ { "id": "A0A8V0YFL8", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YFL8", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00096", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00096", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "101750396", "url": "https://www.ncbi.nlm.nih.gov/gene/101750396", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000157", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000157", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004074", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004074", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015621", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015621", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035897", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035897", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041416", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041416", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:101750396", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:101750396", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YPHIIQD", "url": "https://omabrowser.org/oma/group/YPHIIQD/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YFL8", "url": "https://www.orthodb.org/?gene=A0A8V0YFL8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YTT5", "url": "https://www.orthodb.org/?gene=A0A8V0YTT5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11890", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11890", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11890:SF23", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11890:SF23", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01582", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01582", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF18452", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18452", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_040513307", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040513307", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YFL8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFL8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YFL8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFL8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YTT5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTT5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YTT5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTT5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRPPPFGDRDPLHQLSCSREFSAESPTRLLGFARDCHQYAFATWTESKTILKESLNSSEYQSKLIKKMMLTFYWILALLITGTEVRGINLPGCSHVKPQVWYRAISDEEFVLQCALPDKDATNIYNNSVLKQHEVKWFWHQKDKGHLKAVEESFNVTLQGNALWFKPVRENASGIYICMIREKIPCLKIVLEVQTKAKAKCSGYGTNTLYLLAGNGNSIACPGRKCYSHINKTDVRWYKDGRQVEYRKTRNSLQLVDNEIYLKITYVQDAGIYVCDYDMSDNTTQWTMRTAVTVEVIAKTTIHPPNILYPSSVAILEAELGKPLELECRVQFGFERGTQRVIWKRDNKENLNEKLKQFETIETKETSVCPRYLKGHVLRHVAKLEEVTERDLKSDFICFAQNSVGNATAVIQLKKKQRVFFLYILCSAISILFAFLLCTAFIYQHWIEIVLMYRSYVAHNETTGDGKEFDAFVSYAKTDASESDSAFISEEKFALEILPDVLENKYGYKLCILERDILPGGAYTDEVVTAIRQSRRTIIILSPAYVSGPNIFELQAAVNCALEDKKIKLVLIKFQAFQEPETLPPVVKKALRILPVITWKPSISPAPNKKFWKYMHYHMPMNTTKVLGSCSLKCFFQRLFSLEHR", "length": 645, "header": "tr|A0A8V0YFL8-1|A0A8V0YFL8_CHICK Isoform 1 of Interleukin 18 receptor accessory protein OS=Gallus gallus OX=9031 GN=IL18RAP PE=3 SV=1 CANONICAL=A0A8V0YFL8-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YFL8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFL8/entry#A0A8V0YFL8-1", "sequence": { "sequence": "MRPPPFGDRDPLHQLSCSREFSAESPTRLLGFARDCHQYAFATWTESKTILKESLNSSEYQSKLIKKMMLTFYWILALLITGTEVRGINLPGCSHVKPQVWYRAISDEEFVLQCALPDKDATNIYNNSVLKQHEVKWFWHQKDKGHLKAVEESFNVTLQGNALWFKPVRENASGIYICMIREKIPCLKIVLEVQTKAKAKCSGYGTNTLYLLAGNGNSIACPGRKCYSHINKTDVRWYKDGRQVEYRKTRNSLQLVDNEIYLKITYVQDAGIYVCDYDMSDNTTQWTMRTAVTVEVIAKTTIHPPNILYPSSVAILEAELGKPLELECRVQFGFERGTQRVIWKRDNKENLNEKLKQFETIETKETSVCPRYLKGHVLRHVAKLEEVTERDLKSDFICFAQNSVGNATAVIQLKKKQRVFFLYILCSAISILFAFLLCTAFIYQHWIEIVLMYRSYVAHNETTGDGKEFDAFVSYAKTDASESDSAFISEEKFALEILPDVLENKYGYKLCILERDILPGGAYTDEVVTAIRQSRRTIIILSPAYVSGPNIFELQAAVNCALEDKKIKLVLIKFQAFQEPETLPPVVKKALRILPVITWKPSISPAPNKKFWKYMHYHMPMNTTKVLGSCSLKCFFQRLFSLEHR", "length": 645, "header": "tr|A0A8V0YFL8-1|A0A8V0YFL8_CHICK Isoform 1 of Interleukin 18 receptor accessory protein OS=Gallus gallus OX=9031 GN=IL18RAP PE=3 SV=1 CANONICAL=A0A8V0YFL8-1" }, "locus": { "chromosome": "1", "start_pos": 134050781, "end_pos": 134035871, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033250.1", "url": "https://www.ensembl.org/id/ENSGALT00010033250.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019638.1", "url": "https://www.ensembl.org/id/ENSGALP00010019638.1" } ] } }, { "isoform_ac": "A0A8V0YTT5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFL8/entry#A0A8V0YTT5-1", "sequence": { "sequence": "MMLTFYWILALLITGTEVRGINLPGCSHVKPQVWYRAISDEEFVLQCALPDKDATNIYNNSVLKQHEVKWFWHQKDKGHLKAVEESFNVTLQGNALWFKPVRENASGIYICMIREKIPCLKIVLEVQTKAKAKCSGYGTNTLYLLAGNGNSIACPGRKCYSHINKTDVRWYKDGRQVEYRKTRNSLQLVDNEIYLKITYVQDAGIYVCDYDMSDNTTQWTMRTAVTVEVIAKTTIHPPNILYPSSVAILEAELGKPLELECRVQFGFERGTQRVIWKRDNKENLNEKLKQFETIETKETSVCPRYLKGHVLRHVAKLEEVTERDLKSDFICFAQNSVGNATAVIQLKKKQRVFFLYILCSAISILFAFLLCTAFIYQHWIEIVLMYRSYVAHNETTGDGKEFDAFVSYAKTDASESDSAFISEEKFALEILPDVLENKYGYKLCILERDILPGGAYTDEVVTAIRQSRRTIIILSPAYVSGPNIFELQAAVNCALEDKKIKLVLIKFQAFQEPETLPPVVKKALRILPVITWKPSISPAPNKKFWKYMHYHMPMNTTKVLGSCSLKCFFQRLFSLEHR", "length": 578, "header": "tr|A0A8V0YTT5-1|A0A8V0YTT5_CHICK Computationally mapped isoform of Interleukin 18 receptor accessory protein OS=Gallus gallus OX=9031 GN=IL18RAP PE=3 SV=1 CANONICAL=A0A8V0YFL8-1" }, "locus": { "chromosome": "1", "start_pos": 134050781, "end_pos": 134037457, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033244.1", "url": "https://www.ensembl.org/id/ENSGALT00010033244.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019634.1", "url": "https://www.ensembl.org/id/ENSGALP00010019634.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:101750396", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:101750396", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2K2K7-1", "protein_name": "Interleukin-18 receptor accessory protein", "gene_name": "Il18rap", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLCLGWVFLWFVAGEKTTGFNHSACTTKKLLWTYSARGAENFVLFCDLQELQKQDFSHRSQSSSTLGPAHQPCSGSEKDLSDVQWYMQPRSGGPLEEINRNSPHMQNKGTLRILAPQMNSIWSYICRPRSRRPQDTACCVKTVLEVKPQRNISCGSSAQDEQVLLLGSTGSIHCPSLSCQSDVRSPEMTWYKDGRLLPEYKKNPIEMEDIYDFHQGLYVCDYTQSDNVSSWTVRAVVQVRTIDEDTNVKPDILDPVTDTLDVELGKAFTLPCRVQFGFQRYSKPVIKWYVKESTQEWEISEFVEKRIQSTLKNEVIEHTVFLREVTQRDLSRKFVCFAQNSIGNTTRTIRLRKKEGVVFLYILLGMTVMLVGVLVAAALLYWHWIEVVLLCRTFKNKDETLRDKKEFDAFVSYANWSSPETEATGSLSEEHLALNLFPEVLENTYGYSLCLFERDVTPGGVYTDDIVSIIKRSRRGIFILSPRYINGPRVFELQAAVNLALVDQTLKLILIKFCSFQEPESLPYLVKKALRVLPTVTWKGLKSVHATSRFWTQIRYHMPVKNSNRFMFNWLRLIPKGFSPEKDLATQKPLGGMPNSGNSHGAQNRTPDAGNRHGAQNLLLSGHQKRC", "length": 627 }, "evidence": [ { "id": "A0A8V0YFL8", "url": "https://omabrowser.org/oma/group/A0A8V0YFL8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1MAT8-1", "protein_name": "Interleukin-18 receptor accessory protein", "gene_name": "IL18RAP", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MRLSLGWILLWLVARGRIRGLNTPDCITEKPLRTYSARCGEEFVLFCDLPEPQKSHFYHGSQLSPTRASEYLPCSGSKNLSDVQWYLQPQNGDAAVEITQNAPQVIQEKSNLHFLSTGINHAGLYICRPRMRSPQENACCVRMILEVKPQTNMSCESSVSHKQHLLLGSVSSIYCPGLSHQSDAQSPEVTWYQNGKLLSEKRSNPIEVDEVYYYHQGTYVCDYTQTDNSSSWTVRAVVHVKTIVKNTNLKPDILDPIKDTLEVELGKPLMLNCTARFGFEINFNPVIKWYIRDSDQEWEIKTPKGRSVKSTLKDEVIERVVLLEKVTQSDLHRKFICFAQNSIGNTTQSIQLKKKTGVVFLYILLGAVMGLAGVLTAGALLYMYWIEIVLVYRTYWSKDKTLGDQKEFDAFVSYAKWSPFETEASSSLSEETLALNLLPDVLENKYGYTLCLLERDVAPGGVYTEDIVSIIKKSRRGIFILSPNYVSGPSIFELQAAVNLALEDQTLKLILIKFSSFQEPESLPHLVRRALRVLPSVTWKGLKSVPPNSRFWTQIRYHMPVKSSRGVTWNHLRTMPWIFSLEKTQ", "length": 585 }, "evidence": [ { "id": "A0A8V0YFL8", "url": "https://omabrowser.org/oma/group/A0A8V0YFL8/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "O95256-1", "protein_name": "Interleukin-18 receptor accessory protein", "gene_name": "IL18RAP", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLCLGWIFLWLVAGERIKGFNISGCSTKKLLWTYSTRSEEEFVLFCDLPEPQKSHFCHRNRLSPKQVPEHLPFMGSNDLSDVQWYQQPSNGDPLEDIRKSYPHIIQDKCTLHFLTPGVNNSGSYICRPKMIKSPYDVACCVKMILEVKPQTNASCEYSASHKQDLLLGSTGSISCPSLSCQSDAQSPAVTWYKNGKLLSVERSNRIVVDEVYDYHQGTYVCDYTQSDTVSSWTVRAVVQVRTIVGDTKLKPDILDPVEDTLEVELGKPLTISCKARFGFERVFNPVIKWYIKDSDLEWEVSVPEAKSIKSTLKDEIIERNIILEKVTQRDLRRKFVCFVQNSIGNTTQSVQLKEKRGVVLLYILLGTIGTLVAVLAASALLYRHWIEIVLLYRTYQSKDQTLGDKKDFDAFVSYAKWSSFPSEATSSLSEEHLALSLFPDVLENKYGYSLCLLERDVAPGGVYAEDIVSIIKRSRRGIFILSPNYVNGPSIFELQAAVNLALDDQTLKLILIKFCYFQEPESLPHLVKKALRVLPTVTWRGLKSVPPNSRFWAKMRYHMPVKNSQGFTWNQLRITSRIFQWKGLSRTETTGRSSQPKEW", "length": 599 }, "evidence": [ { "id": "A0A8V0YFL8", "url": "https://omabrowser.org/oma/group/A0A8V0YFL8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9Z2B1-1", "protein_name": "Interleukin-18 receptor accessory protein", "gene_name": "Il18rap", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLCLGWVFLWFVAGEKTTGFNHSACATKKLLWTYSARGAENFVLFCDLQELQEQKFSHASQLSPTQSPAHKPCSGSQKDLSDVQWYMQPRSGSPLEEISRNSPHMQSEGMLHILAPQTNSIWSYICRPRIRSPQDMACCIKTVLEVKPQRNVSCGNTAQDEQVLLLGSTGSIHCPSLSCQSDVQSPEMTWYKDGRLLPEHKKNPIEMADIYVFNQGLYVCDYTQSDNVSSWTVRAVVKVRTIGKDINVKPEILDPITDTLDVELGKPLTLPCRVQFGFQRLSKPVIKWYVKESTQEWEMSVFEEKRIQSTFKNEVIERTIFLREVTQRDLSRKFVCFAQNSIGNTTRTIRLRKKEEVVFVYILLGTALMLVGVLVAAAFLYWYWIEVVLLCRTYKNKDETLGDKKEFDAFVSYSNWSSPETDAVGSLSEEHLALNLFPEVLEDTYGYRLCLLDRDVTPGGVYADDIVSIIKKSRRGIFILSPSYLNGPRVFELQAAVNLALVDQTLKLILIKFCSFQEPESLPYLVKKALRVLPTVTWKGLKSVHASSRFWTQIRYHMPVKNSNRFMFNGLRIFLKGFSPEKDLVTQKPLEGMPKSGNDHGAQNLLLYSDQKRC", "length": 614 }, "evidence": [ { "id": "A0A8V0YFL8", "url": "https://omabrowser.org/oma/group/A0A8V0YFL8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "interleukin-18 receptor complex", "id": "GO:0045092", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045092", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFL8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFL8" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFL8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFL8" } ], "pmid": "" }, { "name": "cell surface", "id": "GO:0009986", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009986", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFL8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFL8" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFL8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFL8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "coreceptor activity", "id": "GO:0015026", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015026", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFL8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFL8" } ], "pmid": "" }, { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFL8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFL8" } ], "pmid": "" }, { "name": "interleukin-1 receptor activity", "id": "GO:0004908", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004908", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFL8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFL8" } ], "pmid": "" }, { "name": "interleukin-18 receptor activity", "id": "GO:0042008", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042008", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFL8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFL8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "interleukin-18-mediated signaling pathway", "id": "GO:0035655", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035655", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFL8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFL8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 126, "end_pos": 128, "annotation": "n_glycosylation_sequon" }, { "start_pos": 155, "end_pos": 157, "annotation": "n_glycosylation_sequon" }, { "start_pos": 171, "end_pos": 173, "annotation": "n_glycosylation_sequon" }, { "start_pos": 231, "end_pos": 233, "annotation": "n_glycosylation_sequon" }, { "start_pos": 282, "end_pos": 284, "annotation": "n_glycosylation_sequon" }, { "start_pos": 406, "end_pos": 408, "annotation": "n_glycosylation_sequon" }, { "start_pos": 460, "end_pos": 462, "annotation": "n_glycosylation_sequon" }, { "start_pos": 56, "end_pos": 58, "annotation": "n_glycosylation_sequon" }, { "start_pos": 622, "end_pos": 624, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YFL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFL8" }, { "id": "PS50835", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50835" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ig-like", "eco_id": "ECO_0000259", "start_pos": 185, "end_pos": 293, "start_aa": "Pro", "end_aa": "Thr", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0YFL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFL8" }, { "id": "PS50104", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50104" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "TIR", "eco_id": "ECO_0000259", "start_pos": 467, "end_pos": 619, "start_aa": "Lys", "end_aa": "Met", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 126, "end_pos": 128 }, { "start_pos": 155, "end_pos": 157 }, { "start_pos": 171, "end_pos": 173 }, { "start_pos": 231, "end_pos": 233 }, { "start_pos": 282, "end_pos": 284 }, { "start_pos": 406, "end_pos": 408 }, { "start_pos": 460, "end_pos": 462 }, { "start_pos": 56, "end_pos": 58 }, { "start_pos": 622, "end_pos": 624 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { 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"field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YFL9-1", "uniprot_ac": "A0A8V0YFL9", "uniprot_id": "A0A8V0YFL9_CHICK", "mass": { "chemical_mass": 27079.0, "monoisotopic_mass": 27079.0 }, "refseq": {}, "gene_names": [ { "name": "FMC1", "type": "recommended", "evidence": [ { "id": "A0A8V0YFL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFL9" } ] } ], "protein_names": [ { "name": "Protein FMC1 homolog", "type": "recommended", "evidence": [ { "id": "A0A8V0YFL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFL9/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Plays a role in the assembly/stability of the mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V).", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Y766", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y766#function" }, { "database": "UniProtKB", "id": "ARBA00045742", "url": "https://www.uniprot.org/uniprotkb/ARBA00045742#function" }, { "database": "UniProtKB", "id": "A0A8V0YFL9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFL9#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFL9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFL9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "FMC1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFL9", "locus": { "chromosome": "1", "start_pos": 49157070, "end_pos": 49155983, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010010929", "url": "https://www.ensembl.org/id/ENSGALG00010010929" } ] } } ], "crossref": [ { "id": "A0A8V0YFL9", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YFL9", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd20271", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd20271", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR037667", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037667", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y766", "url": "https://www.orthodb.org/?gene=A0A8V0Y766", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YFL9", "url": "https://www.orthodb.org/?gene=A0A8V0YFL9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31716", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31716", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31716:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31716:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y766", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y766", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y766-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y766-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YFL9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFL9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YFL9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFL9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "HCSPFSDVRSRRGVSTLSRRWVGAALINVPNAAFATLLVGPADKAEAHHLRLSRFRCAALTPRASTSNVQTQWVGGGCCFGSGAPQRPERASLRPTAEGALDLRHLTSADGRKTARAARSLIGRCSGLPAADWRRERSGKMAALGSPLQTLRGLLRELRHISGRAYRDTAAYRHVLAAFRAHRVTSEKLCRAQQELHFQAATYLCLLRSVRQHQALHREYHGRGERSPEEVAGLVGFRLPRQPGGKG", "length": 247, "header": "tr|A0A8V0YFL9-1|A0A8V0YFL9_CHICK Isoform 1 of Protein FMC1 homolog OS=Gallus gallus OX=9031 GN=FMC1 PE=1 SV=1 CANONICAL=A0A8V0YFL9-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Y766-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFL9/entry#A0A8V0Y766-1", "sequence": { "sequence": "WIRHWPPKPGIVGPADKAEAHHLRLSRFRCAALTPRASTSNVQTQWVGGGCCFGSGAPQRPERASLRPTAEGALDLRHLTSADGRKTARAARSLIGRCSGLPAADWRRERSGKMAALGSPLQTLRGLLRELRHISGRAYRDTAAYRHVLAAFRAHRVTSEKLCRAQQELHFQAATYLCLLRSVRQHQALHREYHGRGERSPEEVAGLVGFRLPRQPGGKG", "length": 220, "header": "tr|A0A8V0Y766-1|A0A8V0Y766_CHICK Computationally mapped isoform of Protein FMC1 homolog OS=Gallus gallus OX=9031 GN=FMC1 PE=1 SV=1 CANONICAL=A0A8V0YFL9-1" }, "locus": { "chromosome": "1", "start_pos": 49157014, "end_pos": 49156092, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026171.1", "url": "https://www.ensembl.org/id/ENSGALT00010026171.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010014795.1", "url": "https://www.ensembl.org/id/ENSGALP00010014795.1" } ] } }, { "isoform_ac": "A0A8V0YFL9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFL9/entry#A0A8V0YFL9-1", "sequence": { "sequence": "HCSPFSDVRSRRGVSTLSRRWVGAALINVPNAAFATLLVGPADKAEAHHLRLSRFRCAALTPRASTSNVQTQWVGGGCCFGSGAPQRPERASLRPTAEGALDLRHLTSADGRKTARAARSLIGRCSGLPAADWRRERSGKMAALGSPLQTLRGLLRELRHISGRAYRDTAAYRHVLAAFRAHRVTSEKLCRAQQELHFQAATYLCLLRSVRQHQALHREYHGRGERSPEEVAGLVGFRLPRQPGGKG", "length": 247, "header": "tr|A0A8V0YFL9-1|A0A8V0YFL9_CHICK Isoform 1 of Protein FMC1 homolog OS=Gallus gallus OX=9031 GN=FMC1 PE=1 SV=1 CANONICAL=A0A8V0YFL9-1" }, "locus": { "chromosome": "1", "start_pos": 49157014, "end_pos": 49156182, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026173.1", "url": "https://www.ensembl.org/id/ENSGALT00010026173.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010014797.1", "url": "https://www.ensembl.org/id/ENSGALP00010014797.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFL9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFL9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YFM2-1", "uniprot_ac": "A0A8V0YFM2", "uniprot_id": "A0A8V0YFM2_CHICK", "mass": { "chemical_mass": 44962.0, "monoisotopic_mass": 44962.0 }, "refseq": {}, "gene_names": [ { "name": "TMEM19", "type": "recommended", "evidence": [ { "id": "A0A8V0YFM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFM2" } ] } ], "protein_names": [ { "name": "Transmembrane protein 19", "type": "recommended", "evidence": [ { "id": "A0A8V0YFM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFM2/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFM2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFM2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TMEM19", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFM2", "locus": { "chromosome": "1", "start_pos": 36536648, "end_pos": 36510531, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012734", "url": "https://www.ensembl.org/id/ENSGALG00010012734" } ] } } ], "crossref": [ { "id": "A0A8V0YFM2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YFM2", "database": "AlphaFoldDB", "categories": [] }, { "id": "417856", "url": "https://www.ncbi.nlm.nih.gov/gene/417856", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002794", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002794", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YAC7", "url": "https://www.orthodb.org/?gene=A0A8V0YAC7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YFM2", "url": "https://www.orthodb.org/?gene=A0A8V0YFM2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YIP9", "url": "https://www.orthodb.org/?gene=A0A8V0YIP9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13353", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13353", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13353:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13353:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01940", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01940", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YAC7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAC7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YAC7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAC7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YFM2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFM2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YFM2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFM2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YIP9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIP9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YIP9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIP9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MHVTAVCGHRAEPTGTGSTKHAHSTLAGLWHRSGSARALTKQWEGIRKPLHAESHWNSQRTANNSPGKAAALWLPMTSNQEDFFRDYLKMLANIVILSLLISVSLAFWIVSMTASTYYGNIRPISPWRWLFSVAVPVVIATQGFKKRSLDHSGALAGLVVGFILTVANYSFFTSLLVFFVTSSKLTKWKKDIKKRIDSEYKEGGQRNWLQVFCNGGIPTELAILYMIESGPGEIPIDFTKYYTASWMCLSLLGALACSAGDTWASEIGSVMSKSKPRLITTWKQVPVGTNGGVTLVGLLSSFLGGMAVGIAYYITQLVFVSDLDVSAPQWPIIVFGAAAGLLGSILDSYLGATMQYSGFDKNTSMVVNYQTRDCQHISGKPILDNNAVNLFSSLLVALVFPAVALCFWPRH", "length": 411, "header": "tr|A0A8V0YFM2-1|A0A8V0YFM2_CHICK Isoform 1 of Transmembrane protein 19 OS=Gallus gallus OX=9031 GN=TMEM19 PE=1 SV=1 CANONICAL=A0A8V0YFM2-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YAC7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFM2/entry#A0A8V0YAC7-1", "sequence": { "sequence": "MFLLAAALWLPMTSNQEDFFRDYLKMLANIVILSLLISVSLAFWIVSMTASTYYGNIRPISPWRWLFSVAVPVVIATQGFKKRSLDHSGALAGLVVGFILTVANYSFFTSLLVFFVTSSKLTKWKKDIKKRIDSEYKEGGQRNWLQVFCNGGIPTELAILYMIESGPGEIPIDFTKYYTASWMCLSLLGALACSAGDTWASEIGSVMSKSKPRLITTWKQVPVGTNGGVTLVGLLSSFLGGMAVGIAYYITQLVFVSDLDVSAPQWPIIVFGAAAGLLGSILDSYLGATMQYSGFDKNTSMVVNYQTRDCQHISGKPILDNNAVNLFSSLLVALVFPAVALCFWPRH", "length": 347, "header": "tr|A0A8V0YAC7-1|A0A8V0YAC7_CHICK Computationally mapped isoform of Transmembrane protein 19 OS=Gallus gallus OX=9031 GN=TMEM19 PE=1 SV=1 CANONICAL=A0A8V0YFM2-1" }, "locus": { "chromosome": "1", "start_pos": 36533147, "end_pos": 36510703, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030481.1", "url": "https://www.ensembl.org/id/ENSGALT00010030481.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017684.1", "url": "https://www.ensembl.org/id/ENSGALP00010017684.1" } ] } }, { "isoform_ac": "A0A8V0YFM2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFM2/entry#A0A8V0YFM2-1", "sequence": { "sequence": "MHVTAVCGHRAEPTGTGSTKHAHSTLAGLWHRSGSARALTKQWEGIRKPLHAESHWNSQRTANNSPGKAAALWLPMTSNQEDFFRDYLKMLANIVILSLLISVSLAFWIVSMTASTYYGNIRPISPWRWLFSVAVPVVIATQGFKKRSLDHSGALAGLVVGFILTVANYSFFTSLLVFFVTSSKLTKWKKDIKKRIDSEYKEGGQRNWLQVFCNGGIPTELAILYMIESGPGEIPIDFTKYYTASWMCLSLLGALACSAGDTWASEIGSVMSKSKPRLITTWKQVPVGTNGGVTLVGLLSSFLGGMAVGIAYYITQLVFVSDLDVSAPQWPIIVFGAAAGLLGSILDSYLGATMQYSGFDKNTSMVVNYQTRDCQHISGKPILDNNAVNLFSSLLVALVFPAVALCFWPRH", "length": 411, "header": "tr|A0A8V0YFM2-1|A0A8V0YFM2_CHICK Isoform 1 of Transmembrane protein 19 OS=Gallus gallus OX=9031 GN=TMEM19 PE=1 SV=1 CANONICAL=A0A8V0YFM2-1" }, "locus": { "chromosome": "1", "start_pos": 36533147, "end_pos": 36520486, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030480.1", "url": "https://www.ensembl.org/id/ENSGALT00010030480.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017683.1", "url": "https://www.ensembl.org/id/ENSGALP00010017683.1" } ] } }, { "isoform_ac": "A0A8V0YIP9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFM2/entry#A0A8V0YIP9-1", "sequence": { "sequence": "MRGAALAAGRDGGAAGGPELQAAALWLPMTSNQEDFFRDYLKMLANIVILSLLISVSLAFWIVSMTASTYYGNIRPISPWRWLFSVAVPVVIATQGFKKRSLDHSGALAGLVVGFILTVANYSFFTSLLVFFVTSSKLTKWKKDIKKRIDSEYKEGGQRNWLQVFCNGGIPTELAILYMIESGPGEIPIDFTKYYTASWMCLSLLGALACSAGDTWASEIGSVMSKSKPRLITTWKQVPVGTNGGVTLVGLLSSFLGGMAVGIAYYITQLVFVSDLDVSAPQWPIIVFGAAAGLLGSILDSYLGATMQYSGFDKNTSMVVNYQTRDCQHISGKPILDNNAVNLFSSLLVALVFPAVALCFWPRH", "length": 364, "header": "tr|A0A8V0YIP9-1|A0A8V0YIP9_CHICK Computationally mapped isoform of Transmembrane protein 19 OS=Gallus gallus OX=9031 GN=TMEM19 PE=1 SV=1 CANONICAL=A0A8V0YFM2-1" }, "locus": { "chromosome": "1", "start_pos": 36533147, "end_pos": 36520773, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030479.1", "url": "https://www.ensembl.org/id/ENSGALT00010030479.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017682.1", "url": "https://www.ensembl.org/id/ENSGALP00010017682.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFM2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFM2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 168, "end_pos": 170, "annotation": "n_glycosylation_sequon" }, { "start_pos": 362, "end_pos": 364, "annotation": "n_glycosylation_sequon" }, { "start_pos": 63, "end_pos": 65, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], 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"field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YFN1-1", "uniprot_ac": "A0A8V0YFN1", "uniprot_id": "A0A8V0YFN1_CHICK", "mass": { "chemical_mass": 21204.0, "monoisotopic_mass": 21204.0 }, "refseq": {}, "gene_names": [ { "name": "MREG", "type": "recommended", "evidence": [ { "id": "A0A8V0YFN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFN1" } ] } ], "protein_names": [ { "name": "Melanoregulin", "type": "synonym", "evidence": [ { "id": "A0A8V0YFN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFN1/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFN1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFN1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MREG", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFN1", "locus": { "chromosome": "7", "start_pos": 4608334, "end_pos": 4613900, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012007", "url": "https://www.ensembl.org/id/ENSGALG00010012007" } ] } } ], "crossref": [ { "id": "A0A8V0YFN1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YFN1", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR031638", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031638", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YFN1", "url": "https://www.orthodb.org/?gene=A0A8V0YFN1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR34340", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR34340", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR34340:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR34340:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15812", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15812", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YFN1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFN1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YFN1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFN1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSPLCSNNNPYASFGATLARDEEQNLWSTPHDVTHTEADDDRVLYNMIVGRSQLDKDSEEWQKLNYDIYTLRQTRKEVRSRWKHILEDLGFQKEADSLLSVTKLSTVSDSQNMSKARDILLKLSEETNIFPTSWELSERYLFVVDRLIALDAADEFFKLASVVYPKRGSMERVDEKYAPVMTP", "length": 183, "header": "tr|A0A8V0YFN1-1|A0A8V0YFN1_CHICK Isoform 1 of Melanoregulin OS=Gallus gallus OX=9031 GN=MREG PE=4 SV=1 CANONICAL=A0A8V0YFN1-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YFN1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFN1/entry#A0A8V0YFN1-1", "sequence": { "sequence": "MSPLCSNNNPYASFGATLARDEEQNLWSTPHDVTHTEADDDRVLYNMIVGRSQLDKDSEEWQKLNYDIYTLRQTRKEVRSRWKHILEDLGFQKEADSLLSVTKLSTVSDSQNMSKARDILLKLSEETNIFPTSWELSERYLFVVDRLIALDAADEFFKLASVVYPKRGSMERVDEKYAPVMTP", "length": 183, "header": "tr|A0A8V0YFN1-1|A0A8V0YFN1_CHICK Isoform 1 of Melanoregulin OS=Gallus gallus OX=9031 GN=MREG PE=4 SV=1 CANONICAL=A0A8V0YFN1-1" }, "locus": { "chromosome": "7", "start_pos": 4613701, "end_pos": 4609723, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028753.1", "url": "https://www.ensembl.org/id/ENSGALT00010028753.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016542.1", "url": "https://www.ensembl.org/id/ENSGALP00010016542.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "phagosome maturation", "id": "GO:0090382", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090382", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFN1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFN1" } ], "pmid": "" }, { "name": "melanosome transport", "id": "GO:0032402", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032402", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFN1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFN1" } ], "pmid": "" }, { "name": "melanocyte differentiation", "id": "GO:0030318", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030318", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFN1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFN1" } ], "pmid": "" }, { "name": "minus-end-directed organelle transport along microtubule", "id": "GO:0072385", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072385", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFN1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFN1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "late endosome membrane", "id": "GO:0031902", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031902", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFN1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFN1" } ], "pmid": "" }, { "name": "melanosome", "id": "GO:0042470", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042470", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFN1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFN1" } ], "pmid": "" }, { "name": "protein-containing complex", "id": "GO:0032991", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032991", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFN1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFN1" } ], "pmid": "" }, { "name": "melanosome membrane", "id": "GO:0033162", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033162", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFN1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFN1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "phosphatidylinositol binding", "id": "GO:0035091", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035091", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFN1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFN1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 112, "end_pos": 114, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 112, "end_pos": 114 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YFP6-1", "uniprot_ac": "A0A8V0YFP6", "uniprot_id": "A0A8V0YFP6_CHICK", "mass": { "chemical_mass": 70571.0, "monoisotopic_mass": 70571.0 }, "refseq": { "ac": "XP_422198", "name": "coagulation factor XIII B chain isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_422198" }, "gene_names": [ { "name": "F13B", "type": "recommended", "evidence": [ { "id": "A0A8V0YFP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFP6" } ] }, { "name": "F13B", "type": "synonym", "evidence": [ { "id": "XP_422198", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_422198" } ] } ], "protein_names": [ { "name": "Coagulation factor XIII B chain", "type": "synonym", "evidence": [ { "id": "A0A8V0YFP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFP6/entry#names_and_taxonomy" } ] }, { "name": "coagulation factor XIII B chain isoform X1", "type": "synonym", "evidence": [ { "id": "XP_422198", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_422198" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052539.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_422198.4. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_422198", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_422198" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFP6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFP6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "F13B", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFP6", "locus": { "chromosome": "8", "start_pos": 2657266, "end_pos": 2650027, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012430", "url": "https://www.ensembl.org/id/ENSGALG00010012430" } ] } } ], "crossref": [ { "id": "A0A8V0YFP6", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YFP6", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00033", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00033", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "424355", "url": "https://www.ncbi.nlm.nih.gov/gene/424355", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000436", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000436", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035976", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035976", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051503", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051503", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YFP2", "url": "https://www.orthodb.org/?gene=A0A8V0YFP2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YFP6", "url": "https://www.orthodb.org/?gene=A0A8V0YFP6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45785", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45785", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45785:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45785:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00084", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00084", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-9769733", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9769733", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_422198", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_422198", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YFP2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFP2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YFP2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFP2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YFP6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFP6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YFP6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFP6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRFKSYFFFLVMMNSGNIFAEDKLCDLPHVENGRIAPYYYSFKGYYFPMRKGKSLSYSCVAGYTTETGTQDGRITCMAKGWSPVPRCYKKCNKPLLEHGVFYGTEMYFNIHEKLQYKCNQGYHAPSGGTEDTVQCQSDGWSSQASCTKTVESCQVPELHHGNYFTTQRELRVNEALLYKCDEGYRTAGGNATEEAVCLAHGWSLTPNCSKKTCPSLGGIEHGGFYPMKKFYEEGDVVHFFCEENYSFREFDLIQCYYFGWYPDPPACEDVTNKCPPPPLPPNAHIIADRRMYRTGDRVRIQCQSGYEIRGSGEIRCEKGKWTSPPICMGSTDKKESETPAVEANATIRASKTYHSEEMKIQQNCTSPPVIKNGVLLAPLLPSYKHGSSIEYGCQRYHLLDGPSTVYCKRGNWTERPTCLDPCILNVTEMNSNNIELKWRQEEFVFLHGDLIEFECKQGYKFPHVTVPSPGRTWCDRGRLKYPKCVFQVPMEKCDSPPSIANGALTLPPLTQYDNGSSVQYSCSEYYFLQGSERIYCSEGRWTSPPLCIEPCTLSKNEMEKNNVLLESFYEDQVYFYHGDYVGFHCKQNHFGAESGATLFQVQCKRGQLAYPRCVERRK", "length": 618, "header": "tr|A0A8V0YFP6-1|A0A8V0YFP6_CHICK Isoform 1 of Coagulation factor XIII B chain OS=Gallus gallus OX=9031 GN=F13B PE=1 SV=1 CANONICAL=A0A8V0YFP6-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YFP2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFP6/entry#A0A8V0YFP2-1", "sequence": { "sequence": "MRFKSYFFFLVMMNSGNIFAEDKLCDLPHVENGRIAPYYYSFKGYYFPMRKGKSLSYSCVAGYTTETGTQDGRITCMAKGWSPVPRCYKKCNKPLLEHGVFYGTEMYFNIHEKLQYKCNQGYHAPSGGTEDTVQCQSDGWSSQASCTKTVESCQVPELHHGNYFTTQRELRVNEALLYKCDEGYRTAGGNATEEAVCLAHGWSLTPNCSKKTCPSLGGIEHGGFYPMKKFYEEGDVVHFFCEENYSFREFDLIQCYYFGWYPDPPACEDVTNKCPPPPLPPNAHIIADRRMYRTGDRVRIQCQSGYEIRGSGEIRCEKGKWTSPPICMGSTDKKESETPAVEANATIRASKTYHSEEMKIQQNCTSPPVIKNGVLLAPLLPSYKHGSSIEYGCQRYHLLDGPSTVYCKRGNWTERPTCLDPCILNVTEMNSNNIELKWRQEEFVFLHGDLIEFECKQGYKFPHVTVPSPGRTWCDRGRLKYPKCVFQVPMEKCDSPPSIANGALTLPPLTQYDNGSSVQYSCSEYYFLQGSERIYCSEGRWTSPPLCIGTHKKIRKIHKHLFPVVRWLSIYRLMLSIYRLSVANWNVIKISTAFWS", "length": 596, "header": "tr|A0A8V0YFP2-1|A0A8V0YFP6_CHICK Computationally mapped isoform of Coagulation factor XIII B chain OS=Gallus gallus OX=9031 GN=F13B PE=1 SV=1 CANONICAL=A0A8V0YFP6-1" }, "locus": { "chromosome": "8", "start_pos": 2655893, "end_pos": 2650074, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029783.1", "url": "https://www.ensembl.org/id/ENSGALT00010029783.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017341.1", "url": "https://www.ensembl.org/id/ENSGALP00010017341.1" } ] } }, { "isoform_ac": "A0A8V0YFP6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFP6/entry#A0A8V0YFP6-1", "sequence": { "sequence": "MRFKSYFFFLVMMNSGNIFAEDKLCDLPHVENGRIAPYYYSFKGYYFPMRKGKSLSYSCVAGYTTETGTQDGRITCMAKGWSPVPRCYKKCNKPLLEHGVFYGTEMYFNIHEKLQYKCNQGYHAPSGGTEDTVQCQSDGWSSQASCTKTVESCQVPELHHGNYFTTQRELRVNEALLYKCDEGYRTAGGNATEEAVCLAHGWSLTPNCSKKTCPSLGGIEHGGFYPMKKFYEEGDVVHFFCEENYSFREFDLIQCYYFGWYPDPPACEDVTNKCPPPPLPPNAHIIADRRMYRTGDRVRIQCQSGYEIRGSGEIRCEKGKWTSPPICMGSTDKKESETPAVEANATIRASKTYHSEEMKIQQNCTSPPVIKNGVLLAPLLPSYKHGSSIEYGCQRYHLLDGPSTVYCKRGNWTERPTCLDPCILNVTEMNSNNIELKWRQEEFVFLHGDLIEFECKQGYKFPHVTVPSPGRTWCDRGRLKYPKCVFQVPMEKCDSPPSIANGALTLPPLTQYDNGSSVQYSCSEYYFLQGSERIYCSEGRWTSPPLCIEPCTLSKNEMEKNNVLLESFYEDQVYFYHGDYVGFHCKQNHFGAESGATLFQVQCKRGQLAYPRCVERRK", "length": 618, "header": "tr|A0A8V0YFP6-1|A0A8V0YFP6_CHICK Isoform 1 of Coagulation factor XIII B chain OS=Gallus gallus OX=9031 GN=F13B PE=1 SV=1 CANONICAL=A0A8V0YFP6-1" }, "locus": { "chromosome": "8", "start_pos": 2656322, "end_pos": 2650074, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029793.1", "url": "https://www.ensembl.org/id/ENSGALT00010029793.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017346.1", "url": "https://www.ensembl.org/id/ENSGALP00010017346.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-9769733", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9769733", "resource": "Reactome", "description": "Fibrin formation" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "blood coagulation", "id": "GO:0007596", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007596", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFP6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFP6" } ], "pmid": "" }, { "name": "blood coagulation, fibrin clot formation", "id": "GO:0072378", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072378", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFP6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFP6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 190, "end_pos": 192, "annotation": "n_glycosylation_sequon" }, { "start_pos": 207, "end_pos": 209, "annotation": "n_glycosylation_sequon" }, { "start_pos": 244, "end_pos": 246, "annotation": "n_glycosylation_sequon" }, { "start_pos": 344, "end_pos": 346, "annotation": "n_glycosylation_sequon" }, { "start_pos": 363, "end_pos": 365, "annotation": "n_glycosylation_sequon" }, { "start_pos": 411, "end_pos": 413, "annotation": "n_glycosylation_sequon" }, { "start_pos": 425, "end_pos": 427, "annotation": "n_glycosylation_sequon" }, { "start_pos": 514, "end_pos": 516, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YFP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFP6" }, { "id": "PS50923", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50923" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Sushi", "eco_id": "ECO_0000259", "start_pos": 89, "end_pos": 148, "start_aa": "Lys", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 190, "end_pos": 192 }, { "start_pos": 207, "end_pos": 209 }, { "start_pos": 244, "end_pos": 246 }, { "start_pos": 344, "end_pos": 346 }, { "start_pos": 363, "end_pos": 365 }, { "start_pos": 411, "end_pos": 413 }, { "start_pos": 425, "end_pos": 427 }, { "start_pos": 514, "end_pos": 516 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YFP8-1", "uniprot_ac": "A0A8V0YFP8", "uniprot_id": "A0A8V0YFP8_CHICK", "mass": { "chemical_mass": 93536.0, "monoisotopic_mass": 93536.0 }, "refseq": { "ac": "XP_004934622", "name": "receptor-interacting serine/threonine-protein kinase 4", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004934622" }, "gene_names": [ { "name": "RIPK4", "type": "recommended", "evidence": [ { "id": "A0A8V0YFP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFP8" } ] }, { "name": "RIPK4", "type": "synonym", "evidence": [ { "id": "XP_004934622", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004934622" } ] } ], "protein_names": [ { "name": "Receptor-interacting serine/threonine-protein kinase 4", "type": "recommended", "evidence": [ { "id": "A0A8V0YFP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFP8/entry#names_and_taxonomy" } ] }, { "name": "2.7.11.1", "type": "synonym", "evidence": [ { "id": "A0A8V0YFP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFP8/entry#names_and_taxonomy" } ] }, { "name": "Ankyrin repeat domain-containing protein 3", "type": "synonym", "evidence": [ { "id": "A0A8V0YFP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFP8/entry#names_and_taxonomy" } ] }, { "name": "receptor-interacting serine/threonine-protein kinase 4", "type": "synonym", "evidence": [ { "id": "XP_004934622", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004934622" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 1, 2022 this sequence version replaced XP_004934622.3. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004934622", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004934622" } ] }, { "annotation": "Serine/threonine protein kinase. Required for embryonic skin development and correct skin homeostasis in adults, via phosphorylation of PKP1 and subsequent promotion of keratinocyte differentiation and cell adhesion. It is a direct transcriptional target of TP63. Plays a role in NF-kappa-B activation.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFP8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFP8#function" }, { "database": "UniProtKB", "id": "ARBA00059729", "url": "https://www.uniprot.org/uniprotkb/ARBA00059729#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFP8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFP8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RIPK4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFP8", "locus": { "chromosome": "1", "start_pos": 109103106, "end_pos": 109124365, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010010941", "url": "https://www.ensembl.org/id/ENSGALG00010010941" } ] } } ], "crossref": [ { "id": "A0A8V0YFP8", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YFP8", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd14025", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14025", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "418529", "url": "https://www.ncbi.nlm.nih.gov/gene/418529", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000719", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000719", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008271", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008271", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011009", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011009", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017441", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017441", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036770", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036770", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:418529", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418529", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HSKENTC", "url": "https://omabrowser.org/oma/group/HSKENTC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YFP4", "url": "https://www.orthodb.org/?gene=A0A8V0YFP4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YFP8", "url": "https://www.orthodb.org/?gene=A0A8V0YFP8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24198", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24198", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24198:SF65", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24198:SF65", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00023", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00023", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00069", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00069", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12796", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12796", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13637", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13637", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_004934622", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004934622", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "17989", "url": "https://www.rhea-db.org/rhea/17989", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "46608", "url": "https://www.rhea-db.org/rhea/46608", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YFP4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFP4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YFP4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFP4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YFP8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFP8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YFP8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFP8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MALPTDRRRELPHSAALCQHHGGGAGTPSLPGPGPAPRGAPDSPGPAGGGGGGAAERGAGRRPRGSMARESGSPWAMGLLKTFEESEFGSWEKIGSGGFGQVYKVRHLHWKTWLAIKCSPSLHVDEKERMELLEEARKMEMAKFRYILPVYGICKEPVGLVMEYMETGSLEKLLASEPLPWELRFRIIHETAVGMNFLHCMSPPLLHLDLKPANILLDAHYHVKISDFGLAKCNGLSHSHDLSMDGLCGTIAYLPPERIKEKNRCFDTKHDVYSFSIVIWGVLTQKKPFAEENNILHIMVKVVKGHRPELPAVSKSRPHSCNNLIKLMQKCWQDDPGERPTFQEITSVTETLCEKPEDETKEMVAEDLDTKSSPKQRSEGMSALSQPKQEPVLASDKDYSLSELLSQLDSGISQTMEGPEDLSRSSSESKLAASDKRLSGVSSVDSAFSSRGSLSLSFERESSDIGTTDIQKRKLTEAILAGDTSKLMKILQPQDVDIVLDGNSSLLHLAVEAGQEECVKWLLLYNANPNLTNKKGSTPLHIAIEKKIKSIVELLMARKINVNAKDEDQWTALHFAAQNGDDFSTKMLLDKNASLNEVDFEGRAPIHIACQYGQENIVRILLRRGVNVNIKGKDDWVPLHYAAWQGHLPIVKLLAKQPGANVNVQTVDGRTSLHLAAQRGHYRVARLLIDLESDVNVPNALSQTALHIAAETGHTSTSRLLLKHGADIEAVTVEGCTALHLASRSGHLATTKLLTDEGANVLARGPLNRTALHLAAENGHSEVVEELVSSGNINVSDDEGLTAFHLAARGGHTKTVEVLLKHGALTDLQRPTFQTLLRLTQQSSNSSVTVLLSET", "length": 855, "header": "tr|A0A8V0YFP8-1|A0A8V0YFP8_CHICK Isoform 1 of Receptor-interacting serine/threonine-protein kinase 4 OS=Gallus gallus OX=9031 GN=RIPK4 PE=3 SV=1 CANONICAL=A0A8V0YFP8-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YFP4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFP8/entry#A0A8V0YFP4-1", "sequence": { "sequence": "MARESGSPWAMGLLKTFEESEFGSWEKIGSGGFGQVYKVRHLHWKTWLAIKCSPSLHVDEKERMELLEEARKMEMAKFRYILPVYGICKEPVGLVMEYMETGSLEKLLASEPLPWELRFRIIHETAVGMNFLHCMSPPLLHLDLKPANILLDAHYHVKNLAEETTLPDYFTFLSFSQVIPVFPYRLKIQISDFGLAKCNGLSHSHDLSMDGLCGTIAYLPPERIKEKNRCFDTKHDVYSFSIVIWGVLTQKKPFAEENNILHIMVKVVKGHRPELPAVSKSRPHSCNNLIKLMQKCWQDDPGERPTFQEITSVTETLCEKPEDETKEMVAEDLDTKSSPKQRSEGMSALSQPKQEPVLASDKDYSLSELLSQLDSGISQTMEGPEDLSRSSSESKLAASDKRLSGVSSVDSAFSSRGSLSLSFERESSDIGTTDIQKRKLTEAILAGDTSKLMKILQPQDVDIVLDGNSSLLHLAVEAGQEECVKWLLLYNANPNLTNKKGSTPLHIAIEKKIKSIVELLMARKINVNAKDEDQWTALHFAAQNGDDFSTKMLLDKNASLNEVDFEGRAPIHIACQYGQENIVRILLRRGVNVNIKGKDDWVPLHYAAWQGHLPIVKLLAKQPGANVNVQTVDGRTSLHLAAQRGHYRVARLLIDLESDVNVPNALSQTALHIAAETGHTSTSRLLLKHGADIEAVTVEGCTALHLASRSGHLATTKLLTDEGANVLARGPLNRTALHLAAENGHSEVVEELVSSGNINVSDDEGLTAFHLAARGGHTKTVEVLLKHGALTDLQRPTFQTLLRLTQQSSNSSVTVLLSET", "length": 820, "header": "tr|A0A8V0YFP4-1|A0A8V0YFP8_CHICK Computationally mapped isoform of Receptor-interacting serine/threonine-protein kinase 4 OS=Gallus gallus OX=9031 GN=RIPK4 PE=3 SV=1 CANONICAL=A0A8V0YFP8-1" }, "locus": { "chromosome": "1", "start_pos": 109123968, "end_pos": 109104165, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026199.1", "url": "https://www.ensembl.org/id/ENSGALT00010026199.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010014823.1", "url": "https://www.ensembl.org/id/ENSGALP00010014823.1" } ] } }, { "isoform_ac": "A0A8V0YFP8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFP8/entry#A0A8V0YFP8-1", "sequence": { "sequence": "MALPTDRRRELPHSAALCQHHGGGAGTPSLPGPGPAPRGAPDSPGPAGGGGGGAAERGAGRRPRGSMARESGSPWAMGLLKTFEESEFGSWEKIGSGGFGQVYKVRHLHWKTWLAIKCSPSLHVDEKERMELLEEARKMEMAKFRYILPVYGICKEPVGLVMEYMETGSLEKLLASEPLPWELRFRIIHETAVGMNFLHCMSPPLLHLDLKPANILLDAHYHVKISDFGLAKCNGLSHSHDLSMDGLCGTIAYLPPERIKEKNRCFDTKHDVYSFSIVIWGVLTQKKPFAEENNILHIMVKVVKGHRPELPAVSKSRPHSCNNLIKLMQKCWQDDPGERPTFQEITSVTETLCEKPEDETKEMVAEDLDTKSSPKQRSEGMSALSQPKQEPVLASDKDYSLSELLSQLDSGISQTMEGPEDLSRSSSESKLAASDKRLSGVSSVDSAFSSRGSLSLSFERESSDIGTTDIQKRKLTEAILAGDTSKLMKILQPQDVDIVLDGNSSLLHLAVEAGQEECVKWLLLYNANPNLTNKKGSTPLHIAIEKKIKSIVELLMARKINVNAKDEDQWTALHFAAQNGDDFSTKMLLDKNASLNEVDFEGRAPIHIACQYGQENIVRILLRRGVNVNIKGKDDWVPLHYAAWQGHLPIVKLLAKQPGANVNVQTVDGRTSLHLAAQRGHYRVARLLIDLESDVNVPNALSQTALHIAAETGHTSTSRLLLKHGADIEAVTVEGCTALHLASRSGHLATTKLLTDEGANVLARGPLNRTALHLAAENGHSEVVEELVSSGNINVSDDEGLTAFHLAARGGHTKTVEVLLKHGALTDLQRPTFQTLLRLTQQSSNSSVTVLLSET", "length": 855, "header": "tr|A0A8V0YFP8-1|A0A8V0YFP8_CHICK Isoform 1 of Receptor-interacting serine/threonine-protein kinase 4 OS=Gallus gallus OX=9031 GN=RIPK4 PE=3 SV=1 CANONICAL=A0A8V0YFP8-1" }, "locus": { "chromosome": "1", "start_pos": 109124166, "end_pos": 109104165, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026204.1", "url": "https://www.ensembl.org/id/ENSGALT00010026204.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010014828.1", "url": "https://www.ensembl.org/id/ENSGALP00010014828.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "gga:418529", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418529", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A9J7GZH5-1", "protein_name": "Receptor-interacting serine/threonine-protein kinase 4", "gene_name": "Ripk4", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MDFFRERMELLEEAKKMEMAKFRYILPVYGICQEPVGLVMEYMETGSLEKLLASEPLPWDLRFRIVHETAVGMNFLHCMSPPLLHLDLKPANILLDAHYHVKISDFGLAKCNGMSHSHDLSMDGLFGTIAYLPPERIREKSRLFDTKHDVYSFAIVIWGMLTQKKPFADEKNILHIMMKVVKGHRPELPPVCRPRPRACANLIGLMQRCWHADPQVRPTFQEITSETEVLCENPDEEVKDLAHEPGEKSSPEPKSEARPESARLKRASAPPFDNDCSLSELLSQLDSGISQTLEGPEELSRSSSECKLPSSSSGKRLSGVSSVDSAFSSRGSLSLSFEREPSTGDLGPTDIQKKKLVDAIMSGDTSKLMKILQPQDVDLVLDSSASLLHLAVEAGQEECVKWLLLNNANPNLTNKKGSTPLHMAVERRGRGIVELLLARKISVNAKDEDQWTALHFAAQNGDEASMRLLLEKNASVNEVDFEGRTPMHVACQHGQENIVRTLLRRGVDVGLQGKDAWLPLHYAAWQGHLSIVKLLAKQPGVSVNAQTLDGRTPLHLAAQRGHYRVARILIDLCSDINICSLQAQTPLHVAAETGHTSTARLLLHRGAGKEALTSEGCTALHLAARNGHLATVKLLVEEKADVLARGPLNQTALHLAAAHGHWEVVEELVSADLIDLSDEQGLSALHLAAQGRHSQTVETLLKHGAHINLQSLKFQGGQSPTATLLRCSKT", "length": 730 }, "evidence": [ { "id": "A0A8V0YFP8", "url": "https://omabrowser.org/oma/group/A0A8V0YFP8/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "D4AAK5-1", "protein_name": "Receptor-interacting serine/threonine-protein kinase 4", "gene_name": "Ripk4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEGEGRGRWALGLLRTFDAGEFAGWEKVGSGGFGQVYKVRHVHWKTWLAIKCSPSLHVDDRERTELLEEAKKMEMAKFRYILPVYGICQEPVGLVMEYMETGSLEKLLASEPLPWDLRFRIVHETAVGMNFLHCMSPPLLHLDLKPANILLDAHYHVKISDFGLAKCNGMSHSHDLSMDGLFGTIAYLPPERIREKSRLFDTKHDVYSFAIVIWGVLTQKKPFSDEKNILHIMMKVVKGHRPELPPICRPRPRACASLIGLMQRCWHADPQVRPTFQEITSETEDLCEKPDEEVKDLAHEPGEKSSPEPRSEARPESSRLKRASAPPFDNDCSLSELLSQLDSGISQTLEGPEELSRSSSECKLPSSSSGKRLSGVSSVDSAFSSRGSLSLSFEREASTGDLGPTDIQKKKLVDAIVSGDTNKLMKILQPQDVDLVLDSSASLLHLAVEAGQEECVKWLLLNNANPNLTNKKGSTPLHMAVERRGRGIVELLLARKTSVNAKDEDQWTALHFAAQNGDEASTRLLLEKNASVNEVDFEGRTPMHVACQHGQENIVRTLLRRGVDVGLQGKDAWLPLHYAAWQGHLPIVKLLAKQPGVSVNAQTLDGRTPLHLAAQRGHYRVARILIDLSSDINICSLQAQTPLHVAAETGHTSTARLLLHRGAGKEALTSEGYTALHLAARNGHLATVKLLIEEKADVLARGPLNQTALHLAAARGHSEVVEELVSADLIDLSDEQGLSALHLAAQGRHSQTVEILLKHGAHINLQSLKFQGGQSSTATLLRRSKT", "length": 786 }, "evidence": [ { "id": "A0A8V0YFP8", "url": "https://omabrowser.org/oma/group/A0A8V0YFP8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P57078-1", "protein_name": "Receptor-interacting serine/threonine-protein kinase 4", "gene_name": "RIPK4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEGDGGTPWALALLRTFDAGEFTGWEKVGSGGFGQVYKVRHVHWKTWLAIKCSPSLHVDDRERMELLEEAKKMEMAKFRYILPVYGICREPVGLVMEYMETGSLEKLLASEPLPWDLRFRIIHETAVGMNFLHCMAPPLLHLDLKPANILLDAHYHVKISDFGLAKCNGLSHSHDLSMDGLFGTIAYLPPERIREKSRLFDTKHDVYSFAIVIWGVLTQKKPFADEKNILHIMVKVVKGHRPELPPVCRARPRACSHLIRLMQRCWQGDPRVRPTFQGNGLNGELIRQVLAALLPVTGRWRSPGEGFRLESEVIIRVTCPLSSPQEITSETEDLCEKPDDEVKETAHDLDVKSPPEPRSEVVPARLKRASAPTFDNDYSLSELLSQLDSGVSQAVEGPEELSRSSSESKLPSSGSGKRLSGVSSVDSAFSSRGSLSLSFEREPSTSDLGTTDVQKKKLVDAIVSGDTSKLMKILQPQDVDLALDSGASLLHLAVEAGQEECAKWLLLNNANPNLSNRRGSTPLHMAVERRVRGVVELLLARKISVNAKDEDQWTALHFAAQNGDESSTRLLLEKNASVNEVDFEGRTPMHVACQHGQENIVRILLRRGVDVSLQGKDAWLPLHYAAWQGHLPIVKLLAKQPGVSVNAQTLDGRTPLHLAAQRGHYRVARILIDLCSDVNVCSLLAQTPLHVAAETGHTSTARLLLHRGAGKEAMTSDGYTALHLAARNGHLATVKLLVEEKADVLARGPLNQTALHLAAAHGHSEVVEELVSADVIDLFDEQGLSALHLAAQGRHAQTVETLLRHGAHINLQSLKFQGGHGPAATLLRRSKT", "length": 832 }, "evidence": [ { "id": "A0A8V0YFP8", "url": "https://omabrowser.org/oma/group/A0A8V0YFP8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9ERK0-1", "protein_name": "Receptor-interacting serine/threonine-protein kinase 4", "gene_name": "Ripk4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEGEGRGRWALGLLRTFDAGEFAGWEKVGSGGFGQVYKVRHVHWKTWLAIKCSPSLHVDDRERMELLEEAKKMEMAKFRYILPVYGICQEPVGLVMEYMETGSLEKLLASEPLPWDLRFRIVHETAVGMNFLHCMSPPLLHLDLKPANILLDAHYHVKISDFGLAKCNGMSHSHDLSMDGLFGTIAYLPPERIREKSRLFDTKHDVYSFAIVIWGVLTQKKPFADEKNILHIMMKVVKGHRPELPPICRPRPRACASLIGLMQRCWHADPQVRPTFQEITSETEDLCEKPDEEVKDLAHEPGEKSSLESKSEARPESSRLKRASAPPFDNDCSLSELLSQLDSGISQTLEGPEELSRSSSECKLPSSSSGKRLSGVSSVDSAFSSRGSLSLSFEREASTGDLGPTDIQKKKLVDAIISGDTSRLMKILQPQDVDLVLDSSASLLHLAVEAGQEECVKWLLLNNANPNLTNRKGSTPLHMAVERKGRGIVELLLARKTSVNAKDEDQWTALHFAAQNGDEASTRLLLEKNASVNEVDFEGRTPMHVACQHGQENIVRTLLRRGVDVGLQGKDAWLPLHYAAWQGHLPIVKLLAKQPGVSVNAQTLDGRTPLHLAAQRGHYRVARILIDLCSDVNICSLQAQTPLHVAAETGHTSTARLLLHRGAGKEALTSEGYTALHLAAQNGHLATVKLLIEEKADVMARGPLNQTALHLAAARGHSEVVEELVSADLIDLSDEQGLSALHLAAQGRHSQTVETLLKHGAHINLQSLKFQGGQSSAATLLRRSKT", "length": 786 }, "evidence": [ { "id": "A0A8V0YFP8", "url": "https://omabrowser.org/oma/group/A0A8V0YFP8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "protein kinase activity", "id": "GO:0004672", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004672", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFP8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFP8" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFP8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFP8" } ], "pmid": "" }, { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFP8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFP8" } ], "pmid": "" }, { "name": "protein serine kinase activity", "id": "GO:0106310", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0106310", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFP8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFP8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFP8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFP8" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFP8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFP8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "intracellular signal transduction", "id": "GO:0035556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035556", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFP8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFP8" } ], "pmid": "" }, { "name": "skin development", "id": "GO:0043588", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043588", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFP8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFP8" } ], "pmid": "" }, { "name": "morphogenesis of an epithelium", "id": "GO:0002009", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002009", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFP8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFP8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 503, "end_pos": 505, "annotation": "n_glycosylation_sequon" }, { "start_pos": 530, "end_pos": 532, "annotation": "n_glycosylation_sequon" }, { "start_pos": 592, "end_pos": 594, "annotation": "n_glycosylation_sequon" }, { "start_pos": 768, "end_pos": 770, "annotation": "n_glycosylation_sequon" }, { "start_pos": 794, "end_pos": 796, "annotation": "n_glycosylation_sequon" }, { "start_pos": 845, "end_pos": 847, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "17989", "name": "", "equation": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q6U1I9-1", "A0A8V0XNJ2-1", "A0A8V0ZUL0-1", "A0A8V0ZT63-1", "A0A8V1ACW2-1", "A0A8V0Z1X0-1", "A0A8V0YHN2-1", "A0A8V0YMN5-1", "A0A8V0Z807-1", "A0A8V0Z930-1", "A0A8V0YFR6-1", "A0A1D5P0M9-1", "A0A8V0ZBN6-1", "A0A3Q2U9U9-1", "A0A8V0YXZ5-1", "A0A8V0ZSP4-1", "A0A8V0ZXQ9-1", "A0A8V0ZZV3-1", "A0A8V1ADF0-1", "A0A8V0ZFT3-1", "A0A8V0ZA45-1", "A0A8V0ZB33-1", "A0A8V0ZD70-1", "A0A8V0Z8T4-1", "R4GIN8-1", "A0A8V0ZK64-1", "A0A8V0ZC16-1", "A0A8V0ZWW1-1", "E1BY69-1", "A0A8V0ZDW9-1", "A0A8V0ZKA2-1", "A0A3Q3B2F1-1", "F1P356-1", "A0A8V1AHA8-1", "Q8QFP8-1", "F1P011-1", "A0A8V0YKK3-1", "A0A1D5NWT4-1", "A0A1D5PMQ7-1", "E1BWA3-1", "F1NVF2-1", "A0A1D5PXN4-1", "A0A3Q2TY19-1", "A0A3Q2U592-1", "A0A8V0XCV5-1", "A0A1D5P8A9-1", "A0A1D5PMG2-1", "A0A8V0X1Q7-1", "A0A8V0Y935-1", "A0A8V0YM96-1", "A0A8V0YF83-1", "A0A8V0YJP9-1", "A0A8V1AKW4-1", "A0A8V0ZSB4-1", "F1NBT0-1", "P18652-1", "P21868-1", "P21869-1", "P53666-1", "P79996-1", "Q5F3W3-1", "Q5ZJS0-1", "Q5ZKN1-1", "Q5ZLL1-1", "A0A8V0XCS0-1", "A0A8V0XNK8-1", "A0A8V0XLV6-1", "A0A8V0XDR5-1", "E1BYH2-1", "E1BQN6-1", "A0A8V0XU71-1", "Q5ZJH6-1", "A0A8V0Y3D1-1", "A0A8V0Y7C3-1", "A0A8V0YCY4-1", "A0A8V0YIV6-1", "A0A8V0YK18-1", "A0A8V0YM22-1", "A0A8V0YTN5-1", "A0A8V0YTP2-1", "Q5F3L1-1", "A0A8V0Y3L2-1", "A0A8V0YCY8-1", "A0A8V0Y9Q1-1", "A0A8V0ZD48-1", "A0A8V0ZD60-1", "A0A8V0ZBZ2-1", "A0A8V0Z9J0-1", "A0A8V1ABF3-1", "Q8AYC9-1", "A0A8V0Z927-1", "A0A8V1A2T9-1", "Q5ZKI0-1", "Q7T0B1-1", "P10741-1", "A0A8V0YFH4-1", "E1C848-1", "A0A8V0X8M1-1", "E1BW33-1", "A0A8V0Z283-1", "A0A8V0Z157-1", "A0A3Q2U4X3-1", "A0A8V0XW11-1", "E1BUG0-1", "A0A8V1ABP4-1", "A0A8V1AJA4-1", "A0A8V1AEH4-1", "F1NJH1-1", "A0A8V1AMK5-1", "A0A3Q2TRY2-1", "A0A8V0X3D6-1", "A0A1D5PD64-1", "A0A8V0XQ97-1", "R4GJB8-1", "A0A8V0X5Z8-1", "A0A8V0XG21-1", "A0A8V0XB58-1", 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[ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XBZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XBZ0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XBZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XBZ0" } ] } ] }, { "uniprot_ac": "A0A8V0XCS0", "gene_name": "PRKG2", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XCS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCS0" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "A0A8V0XCS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCS0" } ] } ] }, { "uniprot_ac": "A0A8V0XCV5", "gene_name": "MAP3K7", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XCV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCV5" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0XCV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCV5" } ] } ] }, { "uniprot_ac": "A0A8V0XCY6", "gene_name": "TTK", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XCY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCY6" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V0XCY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCY6" } ] } ] }, { "uniprot_ac": "A0A8V0XDR5", "gene_name": "IRAK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XDR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XDR5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XDR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XDR5" } ] } ] }, { "uniprot_ac": "A0A8V0XE48", "gene_name": "ROCK2", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XE48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XE48" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "A0A8V0XE48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XE48" } ] } ] }, { "uniprot_ac": "A0A8V0XEA3", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XEA3", "database": "UniProtKB", "url": 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"A0A8V0XI18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XI18" } ] } ] }, { "uniprot_ac": "A0A8V0XKG0", "gene_name": "NEK9", "activity": [ { "ec_number": "2.7.11.38", "activity": "L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XKG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XKG0" } ] }, { "ec_number": "2.7.11.38", "activity": "", "evidence": [ { "id": "A0A8V0XKG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XKG0" } ] } ] }, { "uniprot_ac": "A0A8V0XLV6", "gene_name": "MAPK10", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XLV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XLV6" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0XLV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XLV6" } ] } ] }, { "uniprot_ac": "A0A8V0XMT1", "gene_name": "MOS", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XMT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMT1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XMT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMT1" } ] } ] }, { "uniprot_ac": "A0A8V0XMX8", "gene_name": "MASTL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XMX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMX8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XMX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMX8" } ] } ] }, { "uniprot_ac": "A0A8V0XND6", "gene_name": "RIOK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XND6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XND6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XND6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XND6" } ] } ] }, { "uniprot_ac": "A0A8V0XNJ2", "gene_name": "CDK8", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XNJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNJ2" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XNJ2", "database": "UniProtKB", "url": 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O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XQ14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ14" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0A8V0XQ14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ14" } ] } ] }, { "uniprot_ac": "A0A8V0XQ97", "gene_name": "CDK14", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XQ97", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ97" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0XQ97", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ97" } ] } ] }, { "uniprot_ac": "A0A8V0XQQ4", "gene_name": "NME7", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQQ4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQQ4" } ] } ] }, { "uniprot_ac": "A0A8V0XQS0", "gene_name": "STK24", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XQS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQS0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XQS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQS0" } ] } ] }, { "uniprot_ac": "A0A8V0XS42", "gene_name": "MAP3K4", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XS42", "database": "UniProtKB", "url": 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"url": "https://www.uniprot.org/uniprotkb/A0A8V0Y3L2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0Y3L2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y3L2" } ] } ] }, { "uniprot_ac": "A0A8V0Y457", "gene_name": "PRPF4B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y457", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y457" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y457", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y457" } ] } ] }, { "uniprot_ac": "A0A8V0Y4L8", "gene_name": "HUNK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y4L8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y4L8" } ] }, { 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} ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YGW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGW2" } ] } ] }, { "uniprot_ac": "A0A8V0YHH2", "gene_name": "STK38L", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YHH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHH2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YHH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHH2" } ] } ] }, { "uniprot_ac": "A0A8V0YHN2", "gene_name": "RPS6KA1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YHN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHN2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YHN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHN2" } ] } ] }, { "uniprot_ac": "A0A8V0YIV6", "gene_name": "DYRK1A", "activity": [ { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] }, { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] } ] }, { "uniprot_ac": "A0A8V0YJP9", "gene_name": "RIOK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YJP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJP9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YJP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJP9" } ] } ] }, { "uniprot_ac": "A0A8V0YK18", "gene_name": "CDC42BPB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YK18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK18" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YK18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK18" } ] } ] }, { "uniprot_ac": "A0A8V0YKK3", "gene_name": "MAP4K4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YKK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKK3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YKK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKK3" } ] } ] }, { "uniprot_ac": "A0A8V0YLV1", "gene_name": "MARK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YLV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLV1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YLV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLV1" } ] } ] }, { "uniprot_ac": "A0A8V0YM22", "gene_name": "MYO3AL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YM22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM22" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YM22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM22" } ] } ] }, { "uniprot_ac": "A0A8V0YM96", "gene_name": "STK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YM96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM96" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YM96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM96" } ] } ] }, { "uniprot_ac": "A0A8V0YMB3", "gene_name": "STK32A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YMB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMB3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YMB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMB3" } ] } ] }, { "uniprot_ac": "A0A8V0YMN5", "gene_name": "BRAF", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YMN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMN5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YMN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMN5" } ] } ] }, { "uniprot_ac": "A0A8V0YNI5", "gene_name": "NIM1K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YNI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNI5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YNI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNI5" } ] } ] }, { "uniprot_ac": "A0A8V0YRC9", "gene_name": "TNK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YRC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRC9" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YRC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRC9" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0YRC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRC9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YRC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRC9" } ] } ] }, { "uniprot_ac": "A0A8V0YRN4", "gene_name": "GAK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YRN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRN4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YRN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRN4" } ] } ] }, { "uniprot_ac": "A0A8V0YSH3", "gene_name": "RPS6KA6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YSH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSH3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YSH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSH3" } ] } ] }, { "uniprot_ac": "A0A8V0YTI1", "gene_name": "TSSK6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTI1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTI1" } ] } ] }, { "uniprot_ac": "A0A8V0YTL9", "gene_name": "VRK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTL9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTL9" } ] } ] }, { "uniprot_ac": "A0A8V0YTN5", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTN5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTN5" } ] } ] }, { "uniprot_ac": "A0A8V0YTP2", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTP2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTP2" } ] } ] }, { "uniprot_ac": "A0A8V0YXZ5", "gene_name": "CDC42BPA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YXZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXZ5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YXZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXZ5" } ] } ] }, { "uniprot_ac": "A0A8V0YYX2", "gene_name": "PAK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YYX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYX2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YYX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYX2" } ] } ] }, { "uniprot_ac": "A0A8V0YYZ3", "gene_name": "SPEG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YYZ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYZ3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YYZ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYZ3" } ] } ] }, { "uniprot_ac": "A0A8V0YZ74", "gene_name": "MAP2K5", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZ74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZ74" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V0YZ74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZ74" } ] } ] }, { "uniprot_ac": "A0A8V0YZF2", "gene_name": "PAK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZF2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YZF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZF2" } ] } ] }, { "uniprot_ac": "A0A8V0YZK0", "gene_name": "MAP3K6", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZK0" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0YZK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZK0" } ] } ] }, { "uniprot_ac": "A0A8V0YZM1", "gene_name": "MOK", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZM1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0YZM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZM1" } ] }, { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZM1" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0YZM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZM1" } ] } ] }, { "uniprot_ac": "A0A8V0YZV9", "gene_name": "ATR", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZV9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YZV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZV9" } ] } ] }, { "uniprot_ac": "A0A8V0YZY4", "gene_name": "SBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZY4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YZY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZY4" } ] } ] }, { "uniprot_ac": "A0A8V0Z124", "gene_name": "VRK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z124", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z124" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z124", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z124" } ] } ] }, { "uniprot_ac": "A0A8V0Z157", "gene_name": "MARK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z157", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z157" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z157", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z157" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A8V0Z157", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z157" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z157", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z157" } ] } ] }, { "uniprot_ac": "A0A8V0Z1X0", "gene_name": "MAP4K3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z1X0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1X0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z1X0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1X0" } ] } ] }, { "uniprot_ac": "A0A8V0Z283", "gene_name": "MARK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z283", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z283" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z283", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z283" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A8V0Z283", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z283" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z283", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z283" } ] } ] }, { "uniprot_ac": "A0A8V0Z2E3", "gene_name": "PDIK1L", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z2E3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2E3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z2E3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2E3" } ] } ] }, { "uniprot_ac": "A0A8V0Z2Z3", "gene_name": "AAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z2Z3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2Z3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z2Z3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2Z3" } ] } ] }, { "uniprot_ac": "A0A8V0Z466", "gene_name": "MAP3K19", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z466", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z466" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z466", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z466" } ] } ] }, { "uniprot_ac": "A0A8V0Z6K4", "gene_name": "PIK3R4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z6K4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6K4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z6K4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6K4" } ] } ] }, { "uniprot_ac": "A0A8V0Z6T1", "gene_name": "ERN2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z6T1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6T1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z6T1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6T1" } ] } ] }, { "uniprot_ac": "A0A8V0Z807", "gene_name": "NEK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z807", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z807" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z807", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z807" } ] } ] }, { "uniprot_ac": "A0A8V0Z8G2", "gene_name": "TTBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z8G2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8G2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z8G2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8G2" } ] } ] }, { "uniprot_ac": "A0A8V0Z8T4", "gene_name": "RPS6KC1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z8T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8T4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z8T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8T4" } ] } ] }, { "uniprot_ac": "A0A8V0Z927", "gene_name": "PINK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z927", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z927" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z927", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z927" } ] } ] }, { "uniprot_ac": "A0A8V0Z930", "gene_name": "CAMK2B", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z930", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z930" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V0Z930", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z930" } ] } ] }, { "uniprot_ac": "A0A8V0Z9J0", "gene_name": "CIT", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z9J0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9J0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z9J0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9J0" } ] } ] }, { "uniprot_ac": "A0A8V0ZA06", "gene_name": "CDKL1", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZA06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA06" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0ZA06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA06" } ] } ] }, { "uniprot_ac": "A0A8V0ZA45", "gene_name": "MAP4K5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZA45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA45" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZA45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA45" } ] } ] }, { "uniprot_ac": "A0A8V0ZB33", "gene_name": "CAMK2G", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZB33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB33" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V0ZB33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB33" } ] } ] }, { "uniprot_ac": "A0A8V0ZB38", "gene_name": "CIITA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZB38", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB38" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZB38", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB38" } ] } ] }, { "uniprot_ac": "A0A8V0ZBN6", "gene_name": "MAP2K1", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZBN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBN6" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V0ZBN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBN6" } ] } ] }, { "uniprot_ac": "A0A8V0ZBZ2", "gene_name": "MAP3K9", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZBZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBZ2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0ZBZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBZ2" } ] } ] }, { "uniprot_ac": "A0A8V0ZC16", "gene_name": "KALRN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZC16", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC16" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZC16", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC16" } ] } ] }, { "uniprot_ac": "A0A8V0ZD40", "gene_name": "CDC2L1", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD40" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD40" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A8V0ZD40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD40" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0ZD40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD40" } ] } ] }, { "uniprot_ac": "A0A8V0ZD48", "gene_name": "PRKCE", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD48" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V0ZD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD48" } ] } ] }, { "uniprot_ac": "A0A8V0ZD60", "gene_name": "STK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD60" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZD60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD60" } ] } ] }, { "uniprot_ac": "A0A8V0ZD70", "gene_name": "DCLK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD70" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZD70", "database": "UniProtKB", "url": 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"uniprot_ac": "A0A8V0ZFP1", "gene_name": "TTBK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZFP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFP1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZFP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFP1" } ] } ] }, { "uniprot_ac": "A0A8V0ZFT3", "gene_name": "LRRK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZFT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFT3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZFT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFT3" } ] } ] }, { "uniprot_ac": "A0A8V0ZGY3", "gene_name": "HIPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZGY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGY3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZGY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGY3" } ] } ] }, { "uniprot_ac": "A0A8V0ZH91", "gene_name": "WNK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZH91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH91" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZH91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH91" } ] } ] }, { "uniprot_ac": "A0A8V0ZI32", "gene_name": "STK16", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZI32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI32" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZI32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI32" } ] } ] }, { "uniprot_ac": "A0A8V0ZK64", "gene_name": "PDPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZK64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK64" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZK64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK64" } ] } ] }, { "uniprot_ac": "A0A8V0ZKA2", "gene_name": "EIF2AK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZKA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKA2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZKA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKA2" } ] } ] }, { "uniprot_ac": "A0A8V0ZKM9", "gene_name": "STK36", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZKM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKM9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZKM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKM9" } ] } ] }, { "uniprot_ac": "A0A8V0ZLU3", "gene_name": "TLK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZLU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLU3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZLU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLU3" } ] } ] }, { "uniprot_ac": "A0A8V0ZMK1", "gene_name": "PIKFYVE", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZMK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMK1" } ] }, { "ec_number": "2.7.1.150", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,5-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZMK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMK1" } ] }, { "ec_number": "2.7.1.150", "activity": "", "evidence": [ { "id": "A0A8V0ZMK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMK1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZMK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMK1" } ] } ] }, { "uniprot_ac": "A0A8V0ZNP7", "gene_name": "SGK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZNP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNP7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZNP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNP7" } ] } ] }, { "uniprot_ac": "A0A8V0ZPX2", "gene_name": "ALPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZPX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPX2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZPX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPX2" } ] } ] }, { "uniprot_ac": "A0A8V0ZQJ2", "gene_name": "RPS6KB2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZQJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQJ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZQJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQJ2" } ] } ] }, { "uniprot_ac": "A0A8V0ZQT5", "gene_name": "SLC13A3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZQT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQT5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZQT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQT5" } ] } ] }, { "uniprot_ac": "A0A8V0ZRX1", "gene_name": "SETD6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZRX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRX1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZRX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRX1" } ] }, { "ec_number": "2.1.1.-", "activity": "", "evidence": [ { "id": "A0A8V0ZRX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRX1" } ] } ] }, { "uniprot_ac": "A0A8V0ZSB4", "gene_name": "SIK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZSB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSB4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZSB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSB4" } ] } ] }, { "uniprot_ac": "A0A8V0ZSP4", "gene_name": "PKN2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZSP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSP4" } ] }, { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZSP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSP4" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V0ZSP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSP4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZSP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSP4" } ] } ] }, { "uniprot_ac": "A0A8V0ZT63", "gene_name": "STK25", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZT63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT63" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZT63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT63" } ] } ] }, { "uniprot_ac": "A0A8V0ZUC6", "gene_name": "PAK6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZUC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUC6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZUC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUC6" } ] } ] }, { "uniprot_ac": "A0A8V0ZUL0", "gene_name": "PASK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZUL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUL0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZUL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUL0" } ] } ] }, { "uniprot_ac": "A0A8V0ZUU8", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZUU8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUU8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZUU8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUU8" } ] } ] }, { "uniprot_ac": "A0A8V0ZUU9", "gene_name": "MKNK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZUU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUU9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZUU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUU9" } ] } ] }, { "uniprot_ac": "A0A8V0ZWC7", "gene_name": "EIF2AK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZWC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWC7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZWC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWC7" } ] } ] }, { "uniprot_ac": "A0A8V0ZWW1", "gene_name": "MAP3K12", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZWW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWW1" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0ZWW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWW1" } ] } ] }, { "uniprot_ac": "A0A8V0ZXQ9", "gene_name": "PRKG1", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZXQ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXQ9" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "A0A8V0ZXQ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXQ9" } ] } ] }, { "uniprot_ac": "A0A8V0ZYU6", "gene_name": "TNNI3K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZYU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZYU6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZYU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZYU6" } ] } ] }, { "uniprot_ac": "A0A8V0ZZE4", "gene_name": "OBSCN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZZE4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZE4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZZE4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZE4" } ] } ] }, { "uniprot_ac": "A0A8V0ZZK5", "gene_name": "STK38", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZZK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZK5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZZK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZK5" } ] } ] }, { "uniprot_ac": "A0A8V0ZZV3", "gene_name": "MYO3B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZZV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZV3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZZV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZV3" } ] } ] }, { "uniprot_ac": "A0A8V1A069", "gene_name": "TESK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A069", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A069" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V1A069", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A069" } ] } ] }, { "uniprot_ac": "A0A8V1A0W4", "gene_name": "ULK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A0W4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0W4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A0W4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0W4" } ] } ] }, { "uniprot_ac": "A0A8V1A0Y8", "gene_name": "MAST2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A0Y8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0Y8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A0Y8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0Y8" } ] } ] }, { "uniprot_ac": "A0A8V1A1P3", "gene_name": "SRPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A1P3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1P3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A1P3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1P3" } ] } ] }, { "uniprot_ac": "A0A8V1A1Y7", "gene_name": "CDK2", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A1Y7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1Y7" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V1A1Y7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1Y7" } ] } ] }, { "uniprot_ac": "A0A8V1A2T9", "gene_name": "MAP3K14", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A2T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2T9" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V1A2T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2T9" } ] } ] }, { "uniprot_ac": "A0A8V1A3T8", "gene_name": "MAST3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A3T8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3T8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A3T8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3T8" } ] } ] }, { "uniprot_ac": "A0A8V1A4A1", "gene_name": "CAMKK2", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4A1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4A1" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V1A4A1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4A1" } ] } ] }, { "uniprot_ac": "A0A8V1A4J8", "gene_name": "MAPKAPK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4J8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4J8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A4J8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4J8" } ] } ] }, { "uniprot_ac": "A0A8V1A4Q4", "gene_name": "MAPK3", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4Q4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4Q4" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V1A4Q4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4Q4" } ] } ] }, { "uniprot_ac": "A0A8V1A4V7", "gene_name": "HIPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4V7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4V7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A4V7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4V7" } ] } ] }, { "uniprot_ac": "A0A8V1A513", "gene_name": "DAPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A513", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A513" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A513", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A513" } ] } ] }, { "uniprot_ac": "A0A8V1A675", "gene_name": "CSNK1G2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A675", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A675" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A675", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A675" } ] } ] }, { "uniprot_ac": "A0A8V1A7E0", "gene_name": "DYRK3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7E0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E0" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V1A7E0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E0" } ] } ] }, { "uniprot_ac": "A0A8V1A7E9", "gene_name": "SIK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7E9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A7E9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E9" } ] } ] }, { "uniprot_ac": "A0A8V1A7M0", "gene_name": "STK39", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7M0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7M0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A7M0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7M0" } ] } ] }, { "uniprot_ac": "A0A8V1A7P9", "gene_name": "DCAF1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A7P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P9" } ] } ] }, { "uniprot_ac": "A0A8V1A9S5", "gene_name": "NUAK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A9S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9S5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A9S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9S5" } ] } ] }, { "uniprot_ac": "A0A8V1ABF3", "gene_name": "PRKAA2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] } ] }, { "uniprot_ac": "A0A8V1ABP4", "gene_name": "DSTYK", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABP4" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V1ABP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABP4" } ] } ] }, { "uniprot_ac": "A0A8V1ABR8", "gene_name": "CAMK4L", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABR8" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V1ABR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABR8" } ] } ] }, { "uniprot_ac": "A0A8V1AC40", "gene_name": "CDK18", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AC40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC40" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V1AC40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC40" } ] } ] }, { "uniprot_ac": "A0A8V1ACB5", "gene_name": "MAPK13", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACB5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V1ACB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACB5" } ] } ] }, { "uniprot_ac": "A0A8V1ACF6", "gene_name": "PIM1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACF6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ACF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACF6" } ] } ] }, { "uniprot_ac": "A0A8V1ACK0", "gene_name": "MAPKAPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACK0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ACK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACK0" } ] } ] }, { "uniprot_ac": "A0A8V1ACW2", "gene_name": "WNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACW2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ACW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACW2" } ] } ] }, { "uniprot_ac": "A0A8V1ADF0", "gene_name": "MAP2K2", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ADF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADF0" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V1ADF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADF0" } ] } ] }, { "uniprot_ac": "A0A8V1ADN9", "gene_name": "NLK", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ADN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADN9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V1ADN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADN9" } ] } ] }, { "uniprot_ac": "A0A8V1ADT4", "gene_name": "MKNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ADT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADT4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ADT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADT4" } ] } ] }, { "uniprot_ac": "A0A8V1AE45", "gene_name": "ERN1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AE45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE45" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AE45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE45" } ] } ] }, { "uniprot_ac": "A0A8V1AEH4", "gene_name": "STK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AEH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEH4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AEH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEH4" } ] } ] }, { "uniprot_ac": "A0A8V1AFS4", "gene_name": "STKLD1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AFS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFS4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AFS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFS4" } ] } ] }, { "uniprot_ac": "A0A8V1AG70", "gene_name": "LOC100857512", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AG70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AG70" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AG70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AG70" } ] } ] }, { "uniprot_ac": "A0A8V1AH12", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AH12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH12" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AH12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH12" } ] } ] }, { "uniprot_ac": "A0A8V1AHA8", "gene_name": "NEK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AHA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHA8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AHA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHA8" } ] } ] }, { "uniprot_ac": "A0A8V1AIY7", "gene_name": "AATK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AIY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIY7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AIY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIY7" } ] } ] }, { "uniprot_ac": "A0A8V1AJA4", "gene_name": "RPS6KB1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AJA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJA4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AJA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJA4" } ] } ] }, { "uniprot_ac": "A0A8V1AKW4", "gene_name": "MAP2K4", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AKW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKW4" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V1AKW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKW4" } ] } ] }, { "uniprot_ac": "A0A8V1AM12", "gene_name": "GSG2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AM12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM12" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AM12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM12" } ] } ] }, { "uniprot_ac": "A0A8V1AMK5", "gene_name": "PRKCA", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AMK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMK5" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V1AMK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMK5" } ] } ] }, { "uniprot_ac": "A0A8V1AMQ2", "gene_name": "CAMKK1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AMQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMQ2" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V1AMQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMQ2" } ] } ] }, { "uniprot_ac": "A0A8V1AP60", "gene_name": "KSR1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AP60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP60" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AP60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP60" } ] } ] }, { "uniprot_ac": "E1BQN6", "gene_name": "PRKCZ", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BQN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQN6" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1BQN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQN6" } ] } ] }, { "uniprot_ac": "E1BQV7", "gene_name": "SLK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BQV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQV7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BQV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQV7" } ] } ] }, { "uniprot_ac": "E1BUG0", "gene_name": "CDK12", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] } ] }, { "uniprot_ac": "E1BW33", "gene_name": "SMG1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BW33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BW33" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BW33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BW33" } ] } ] }, { "uniprot_ac": "E1BWA3", "gene_name": "PRKCI", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BWA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWA3" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1BWA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWA3" } ] } ] }, { "uniprot_ac": "E1BWT0", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BWT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWT0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BWT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWT0" } ] } ] }, { "uniprot_ac": "E1BX69", "gene_name": "EIF2AK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BX69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BX69" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BX69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BX69" } ] } ] }, { "uniprot_ac": "E1BY69", "gene_name": "PIM3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BY69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BY69" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BY69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BY69" } ] } ] }, { "uniprot_ac": "E1BYH2", "gene_name": "TAOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BYH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BYH2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BYH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BYH2" } ] } ] }, { "uniprot_ac": "E1C093", "gene_name": "PIK3CG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.154", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.154", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] } ] }, { "uniprot_ac": "E1C2I2", "gene_name": "MASTL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C2I2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C2I2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C2I2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C2I2" } ] } ] }, { "uniprot_ac": "E1C581", "gene_name": "TBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C581", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C581" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C581", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C581" } ] } ] }, { "uniprot_ac": "E1C6T4", "gene_name": "PRKD3", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C6T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C6T4" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1C6T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C6T4" } ] } ] }, { "uniprot_ac": "E1C764", "gene_name": "BMP2K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C764", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C764" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C764", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C764" } ] } ] }, { "uniprot_ac": "E1C848", "gene_name": "MAP3K8", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C848", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C848" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1C848", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C848" } ] } ] }, { "uniprot_ac": "F1NA68", "gene_name": "CDK3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NA68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NA68" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1NA68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NA68" } ] } ] }, { "uniprot_ac": "F1NB57", "gene_name": "PLK2", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NB57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NB57" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "F1NB57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NB57" } ] } ] }, { "uniprot_ac": "F1NBT0", "gene_name": "STK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NBT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NBT0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1NBT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NBT0" } ] } ] }, { "uniprot_ac": "F1NCX7", "gene_name": "PLK1", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NCX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCX7" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "F1NCX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCX7" } ] } ] }, { "uniprot_ac": "F1NCY7", "gene_name": "MAPKAPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NCY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCY7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1NCY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCY7" } ] } ] }, { "uniprot_ac": "F1NJH1", "gene_name": "PRKCH", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NJH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NJH1" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1NJH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NJH1" } ] } ] }, { "uniprot_ac": "F1NKW3", "gene_name": "MAP3K15", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NKW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NKW3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1NKW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NKW3" } ] } ] }, { "uniprot_ac": "F1NLR7", "gene_name": "CLK3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NLR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NLR7" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "F1NLR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NLR7" } ] } ] }, { "uniprot_ac": "F1NUX4", "gene_name": "MTOR", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NUX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NUX4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1NUX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NUX4" } ] } ] }, { "uniprot_ac": "F1NVF2", "gene_name": "MAP2K6", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NVF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NVF2" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "F1NVF2", "database": "UniProtKB", 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Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. 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}, { "id": "A0A8V0YFR1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFR1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAQLYYKKVNYSPYRDRIPLQIVRAEAELSVEEKAYLSAVEKGDYASVKHALQEAEIYYNININCMDPLGRSALLIAIENENLEIMELLLSHCVYVGDALLYAIRKEVVGAVELLLNYRKPSGEKQVPTLMMDTQFSEFTPDITPIMLAAHTNNYEIIKLLVQRRVTIPRPHQIRCNCVECVSSSEVDSLRHSRSRLNIYKALASPSLIALSSEDPILTAFRLGWELKELSKVENEFKAEYEELSQQCKRFAKDLLDQARSSRELEIILNHRDDQSEELDPQKCHDLAKLKVAIKYHQKEFVAQPNCQQLLATLWYDGFPGWRRKHWAVKLLTCVTIGLLFPVLSVAYLIAPKSRLGLFIKKPFIKFICHTGSYLTFLFLLLLASQHIVRTDLHMQGPPPTIVEWMILPWVLGFIWGEIKEMWDGGFNEYVHDWWNLMDFAMNSLYLATISLKIVAYVKYNGSRPREEWEMWHPTLIAEALFAISNILSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAFANGLNQLYFYYETSASEEPNNCKGIRCEKQNNAFSTLFETLQSLFWSVFGLLNLYVTNVKARHEFTEFVGATMFGTYNVISLVVLLNMLIAMMNNSYQLIADHADIEWKFARTKLWMSYFDEGATLPPPFNIIPSPKSFWYLCKWIHNQLCPGNDSDNEQKRHENLKTFTERHADNLIQNQHYQEVIRNLVKRYVAAMIRTSKTNEGLTEENFKELKQDISSFRYEVLDLLGNRKPQRRSYSTSSTEVSQKDETNEDSAGEKPKVKSVSFNVANKKKDFNVSALIKTMSGIDMVEEKPKSNGISKRSFIRNGNRVQRLSSSKKESFKRLGLLFSKMNGHVPEANSEPMYTISDGIIQPHYMWKDIKYSQIDKEREENCSKSEINLNEVDYSGNTRLTGQSKECPVVCTSSLHCASSICSSNSKLLDSSEDVFDSWGEACDLFINQWKDGQEDHVTTRL", "length": 989, "header": "tr|A0A8V0YFR1-1|A0A8V0YFR1_CHICK Isoform 1 of Transient receptor potential cation channel subfamily C member 5 OS=Gallus gallus OX=9031 GN=TRPC5 PE=4 SV=1 CANONICAL=A0A8V0YFR1-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YFR1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFR1/entry#A0A8V0YFR1-1", "sequence": { "sequence": "MAQLYYKKVNYSPYRDRIPLQIVRAEAELSVEEKAYLSAVEKGDYASVKHALQEAEIYYNININCMDPLGRSALLIAIENENLEIMELLLSHCVYVGDALLYAIRKEVVGAVELLLNYRKPSGEKQVPTLMMDTQFSEFTPDITPIMLAAHTNNYEIIKLLVQRRVTIPRPHQIRCNCVECVSSSEVDSLRHSRSRLNIYKALASPSLIALSSEDPILTAFRLGWELKELSKVENEFKAEYEELSQQCKRFAKDLLDQARSSRELEIILNHRDDQSEELDPQKCHDLAKLKVAIKYHQKEFVAQPNCQQLLATLWYDGFPGWRRKHWAVKLLTCVTIGLLFPVLSVAYLIAPKSRLGLFIKKPFIKFICHTGSYLTFLFLLLLASQHIVRTDLHMQGPPPTIVEWMILPWVLGFIWGEIKEMWDGGFNEYVHDWWNLMDFAMNSLYLATISLKIVAYVKYNGSRPREEWEMWHPTLIAEALFAISNILSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAFANGLNQLYFYYETSASEEPNNCKGIRCEKQNNAFSTLFETLQSLFWSVFGLLNLYVTNVKARHEFTEFVGATMFGTYNVISLVVLLNMLIAMMNNSYQLIADHADIEWKFARTKLWMSYFDEGATLPPPFNIIPSPKSFWYLCKWIHNQLCPGNDSDNEQKRHENLKTFTERHADNLIQNQHYQEVIRNLVKRYVAAMIRTSKTNEGLTEENFKELKQDISSFRYEVLDLLGNRKPQRRSYSTSSTEVSQKDETNEDSAGEKPKVKSVSFNVANKKKDFNVSALIKTMSGIDMVEEKPKSNGISKRSFIRNGNRVQRLSSSKKESFKRLGLLFSKMNGHVPEANSEPMYTISDGIIQPHYMWKDIKYSQIDKEREENCSKSEINLNEVDYSGNTRLTGQSKECPVVCTSSLHCASSICSSNSKLLDSSEDVFDSWGEACDLFINQWKDGQEDHVTTRL", "length": 989, "header": "tr|A0A8V0YFR1-1|A0A8V0YFR1_CHICK Isoform 1 of Transient receptor potential cation channel subfamily C member 5 OS=Gallus gallus OX=9031 GN=TRPC5 PE=4 SV=1 CANONICAL=A0A8V0YFR1-1" }, "locus": { "chromosome": "4", "start_pos": 13099070, "end_pos": 13037796, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033355.1", "url": "https://www.ensembl.org/id/ENSGALT00010033355.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019683.1", "url": "https://www.ensembl.org/id/ENSGALP00010019683.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:422337", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422337", "resource": "KEGG Pathway" }, { "id": "R-GGA-3295583", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3295583", "resource": "Reactome", "description": "TRP channels" } ], "orthologs": [ { "uniprot_canonical_ac": "F1RWU0-1", "protein_name": "Transient receptor potential cation channel subfamily C member 5", "gene_name": "TRPC5", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAQLYYKKVNYSPYRDRIPLQIVRAETELSAEEKAFLNAVEKGDYATVKQALQEAEIYYNVNINCMDPLGRSALLIAIENENLEIMELLLNHSVYVGDALLYAIRKEVVGAVELLLSYRRPSGEKQVPTLMMDTQFSEFTPDITPIMLAAHTNNYEIIKLLVQKRVTIPRPHQIRCNCVECVSSSEVDSLRHSRSRLNIYKALASPSLIALSSEDPILTAFRLGWELKELSKVENEFKAEYEELSQQCKLFAKDLLDQARSSRELEIILNHRDDHSEELDPQKYHDLAKLKVAIKYHQKEFVAQPNCQQLLATLWYDGFPGWRRKHWVVKLLTCMTIGFLFPMLSIAYLISPRSNLGLFIKKPFIKFICHTASYLTFLFMLLLASQHIVRTDLHVQGPPPTVVEWMILPWVLGFIWGEIKEMWDGGFTEYIHDWWNLMDFAMNSLYLATISLKIVAYVKYNGSRPREEWEMWHPTLIAEALFAISNILSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAFANGLNQLYFYYETRAIDEPNNCKGIRCEKQNNAFSTLFETLQSLFWSVFGLLNLYVTNVKARHEFTEFVGATMFGTYNVISLVVLLNMLIAMMNNSYQLIADHADIEWKFARTKLWMSYFDEGGTLPPPFNIIPSPKSFLYLGNWFNNTFCPKRDPDGRRRRHNLRSFTERHADSLIQNQHYQEVIRNLVKRYVAAMIRNSKTNEGLTEENFKELKQDISSFRYEVLDLLGNRKHPRRSFSTSSTELSQRDDTNDGSGGARAKSKSVSFNLGCKKKACHGPPLIRTTPRVSGAQGKSKAESSSKRSFMGPSLKKLGLLFSKFNGHMSEPSSEPMYTISDGIVQQHYMWQDVRYSQMEKGKAEACSQSEINLSEVELGEARGAAQSSECPLACSSSLHCASSICSSNSKLLDSSEDVFETWGEACDLLMHKWGDGQEEQVTTRL", "length": 974 }, "evidence": [ { "id": "A0A8V0YFR1", "url": "https://omabrowser.org/oma/group/A0A8V0YFR1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q9QX29-1", "protein_name": "Short transient receptor potential channel 5", "gene_name": "Trpc5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAQLYYKKVNYSPYRDRIPLQIVRAETELSAEEKAFLSAVEKGDYATVKQALQEAEIYYNVNINCMDPLGRSALLIAIENENLEIMELLLNHSVYVGDALLYAIRKEVVGAVELLLSYRKPSGEKQVPTLMMDTQFSEFTPDITPIMLAAHTNNYEIIKLLVQKRVTIPRPHQIRCNCVECVSSSEVDSLRHSRSRLNIYKALASPSLIALSSEDPILTAFRLGWELKELSKVENEFKAEYEELSQQCKLFAKDLLDQARSSRELEIILNHRDDHSEELDPQKYHDLAKLKVAIKYHQKEFVAQPNCQQLLATLWYDGFPGWRRKHWVVKLLTCMTIGFLFPMLSIAYLISPRSNLGLFIKKPFIKFICHTASYLTFLFMLLLASQHIVRTDLHVQGPPPTVVEWMILPWVLGFIWGEIKEMWDGGFTEYIHDWWNLMDFAMNSLYLATISLKIVAYVKYNGSRPREEWEMWHPTLIAEALFAISNILSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAFANGLNQLYFYYETRAIDEPNNCKGIRCEKQNNAFSTLFETLQSLFWSVFGLLNLYVTNVKARHEFTEFVGATMFGTYNVISLVVLLNMLIAMMNNSYQLIADHADIEWKFARTKLWMSYFDEGGTLPPPFNIIPSPKSFLYLGNWFNNTFCPKRDPDGRRRRHNLRSFTERHADSLIQNQHYQEVIRNLVKRYVAAMIRNSKTNEGLTEENFKELKQDISSFRYEVLDLLGNRKHPRRSLSTSSADFSQRDDTNDGSGGARAKSKSVSFNVGCKKKACHGAPLIRTVPRASGAQGKPKSESSSKRSFMGPSFKKLGLFFSKFNGQTSEPTSEPMYTISDGIAQQHCMWQDIRYSQMEKGKAEACSQSQMNLGEVELGEIRGAAARSSECPLACSSSLHCASGICSSNSKLLDSSEDVFETWGEACDLLMHKWGDGQEEQVTTRL", "length": 975 }, "evidence": [ { "id": "A0A8V0YFR1", "url": "https://omabrowser.org/oma/group/A0A8V0YFR1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9UL62-1", "protein_name": "Short transient receptor potential channel 5", "gene_name": "TRPC5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAQLYYKKVNYSPYRDRIPLQIVRAETELSAEEKAFLNAVEKGDYATVKQALQEAEIYYNVNINCMDPLGRSALLIAIENENLEIMELLLNHSVYVGDALLYAIRKEVVGAVELLLSYRRPSGEKQVPTLMMDTQFSEFTPDITPIMLAAHTNNYEIIKLLVQKRVTIPRPHQIRCNCVECVSSSEVDSLRHSRSRLNIYKALASPSLIALSSEDPILTAFRLGWELKELSKVENEFKAEYEELSQQCKLFAKDLLDQARSSRELEIILNHRDDHSEELDPQKYHDLAKLKVAIKYHQKEFVAQPNCQQLLATLWYDGFPGWRRKHWVVKLLTCMTIGFLFPMLSIAYLISPRSNLGLFIKKPFIKFICHTASYLTFLFMLLLASQHIVRTDLHVQGPPPTVVEWMILPWVLGFIWGEIKEMWDGGFTEYIHDWWNLMDFAMNSLYLATISLKIVAYVKYNGSRPREEWEMWHPTLIAEALFAISNILSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAFANGLNQLYFYYETRAIDEPNNCKGIRCEKQNNAFSTLFETLQSLFWSVFGLLNLYVTNVKARHEFTEFVGATMFGTYNVISLVVLLNMLIAMMNNSYQLIADHADIEWKFARTKLWMSYFDEGGTLPPPFNIIPSPKSFLYLGNWFNNTFCPKRDPDGRRRRRNLRSFTERNADSLIQNQHYQEVIRNLVKRYVAAMIRNSKTHEGLTEENFKELKQDISSFRYEVLDLLGNRKHPRSFSTSSTELSQRDDNNDGSGGARAKSKSVSFNLGCKKKTCHGPPLIRTMPRSSGAQGKSKAESSSKRSFMGPSLKKLGLLFSKFNGHMSEPSSEPMYTISDGIVQQHCMWQDIRYSQMEKGKAEACSQSEINLSEVELGEVQGAAQSSECPLACSSSLHCASSICSSNSKLLDSSEDVFETWGEACDLLMHKWGDGQEEQVTTRL", "length": 973 }, "evidence": [ { "id": "A0A8V0YFR1", "url": "https://omabrowser.org/oma/group/A0A8V0YFR1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "inositol 1,4,5 trisphosphate binding", "id": "GO:0070679", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070679", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFR1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFR1" } ], "pmid": "" }, { "name": "store-operated calcium channel activity", "id": "GO:0015279", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015279", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFR1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFR1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "cation channel complex", "id": "GO:0034703", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034703", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFR1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFR1" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFR1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFR1" } ], "pmid": "" }, { "name": "calcium channel complex", "id": "GO:0034704", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034704", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFR1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFR1" } ], "pmid": "" }, { "name": "presynapse", "id": "GO:0098793", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098793", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFR1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFR1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "neuron apoptotic process", "id": "GO:0051402", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051402", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFR1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFR1" } ], "pmid": "" }, { "name": "regulation of cytosolic calcium ion concentration", "id": "GO:0051480", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051480", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFR1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFR1" } ], "pmid": "" }, { "name": "calcium ion transmembrane transport", "id": "GO:0070588", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070588", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFR1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFR1" } ], "pmid": "" }, { "name": "phosphatidylserine exposure on apoptotic cell surface", "id": "GO:0070782", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070782", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFR1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFR1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 10, "end_pos": 12, "annotation": "n_glycosylation_sequon" }, { "start_pos": 461, "end_pos": 463, "annotation": "n_glycosylation_sequon" }, { "start_pos": 625, "end_pos": 627, "annotation": "n_glycosylation_sequon" }, { "start_pos": 685, "end_pos": 687, "annotation": "n_glycosylation_sequon" }, { "start_pos": 811, "end_pos": 813, "annotation": "n_glycosylation_sequon" }, { "start_pos": 908, "end_pos": 910, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "29671", "name": "", "equation": "Ca(2+)(in) = Ca(2+)(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YTN5-1", "A0A8V0YTP2-1" ], "evidence": [ { "id": "29671", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/29671" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A8V0YTN5", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTN5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTN5" } ] } ] }, { "uniprot_ac": "A0A8V0YTP2", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTP2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTP2" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YFR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFR1" }, { "id": "SM01420", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM01420" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Transient receptor ion channel", "eco_id": "ECO_0000259", "start_pos": 176, "end_pos": 238, "start_aa": "Cys", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 10, "end_pos": 12 }, { "start_pos": 461, "end_pos": 463 }, { "start_pos": 625, "end_pos": 627 }, { "start_pos": 685, "end_pos": 687 }, { "start_pos": 811, "end_pos": 813 }, { "start_pos": 908, "end_pos": 910 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": 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"sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YFR5-1", "uniprot_ac": "A0A8V0YFR5", "uniprot_id": "A0A8V0YFR5_CHICK", "mass": { "chemical_mass": 36507.0, "monoisotopic_mass": 36507.0 }, "refseq": { "ac": "XP_040511374", "name": "follistatin isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040511374" }, "gene_names": [ { "name": "FST", "type": "recommended", "evidence": [ { "id": "A0A8V0YFR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFR5" } ] }, { "name": "FST", "type": "synonym", "evidence": [ { "id": "XP_040511374", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040511374" } ] } ], "protein_names": [ { "name": "Follistatin", "type": "recommended", "evidence": [ { "id": "A0A8V0YFR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFR5/entry#names_and_taxonomy" } ] }, { "name": "Activin-binding protein", "type": "synonym", "evidence": [ { "id": "A0A8V0YFR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFR5/entry#names_and_taxonomy" } ] }, { "name": "follistatin isoform X1", "type": "synonym", "evidence": [ { "id": "XP_040511374", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040511374" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 2% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052572.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040511374", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040511374" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFR5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFR5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "FST", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFR5", "locus": { "chromosome": "Z", "start_pos": 16618886, "end_pos": 16612237, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012441", "url": "https://www.ensembl.org/id/ENSGALG00010012441" } ] } } ], "crossref": [ { "id": "A0A8V0YFR5", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YFR5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000014908", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000014908", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00104", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00104", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "396119", "url": "https://www.ncbi.nlm.nih.gov/gene/396119", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002350", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002350", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003645", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003645", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015369", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015369", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017878", "url": 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"MFPVGADCKTCWGWAGNCWLRQARNGRCQVLYKTDLSKEECCKSGRLTTSWTEEDVNDNTLFKWMIFNGGAPNCIPCKETCENVDCGPGKKCKMNKKNKPRCVCAPDCSNITWKGPVCGLDGKTYRNECALLKARCKEQPELEVQYQGKCKKTCRDVLCPGSSTCVVDQTNNAYCVTCNRICPEPTSPEQYLCGNDGITYASACHLRKATCLLGRSIGLAYEGKCIKAKSCEDIQCSAGKKCLWDFKVGRGRCALCDELCPESKSDEAVCASDNTTYPSECAMKEAACSMGVLLEVKHSGSCNSINEDPEEEEEDEDQDYSFPISSILEW", "length": 330, "header": "tr|A0A8V0YFR5-1|A0A8V0YFR5_CHICK Isoform 1 of Follistatin OS=Gallus gallus OX=9031 GN=FST PE=4 SV=1 CANONICAL=A0A8V0YFR5-1" }, "isoforms": [ { "isoform_ac": "A0A1I7Q421-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFR5/entry#A0A1I7Q421-1", "sequence": { "sequence": "MLNQRIHPGMLVLLMFLYHFMEDHTAQAGNCWLRQARNGRCQVLYKTDLSKEECCKSGRLTTSWTEEDVNDNTLFKWMIFNGGAPNCIPCKETCENVDCGPGKKCKMNKKNKPRCVCAPDCSNITWKGPVCGLDGKTYRNECALLKARCKEQPELEVQYQGKCKKTCRDVLCPGSSTCVVDQTNNAYCVTCNRICPEPTSPEQYLCGNDGITYASACHLRKATCLLGRSIGLAYEGKCIKAKSCEDIQCSAGKKCLWDFKVGRGRCALCDELCPESKSDEAVCASDNTTYPSECAMKEAACSMGVLLEVKHSGSCN", "length": 316, "header": "tr|A0A1I7Q421-1|A0A1I7Q421_CHICK Computationally mapped isoform of Follistatin OS=Gallus gallus OX=9031 GN=FST PE=4 SV=2 CANONICAL=A0A8V0YFR5-1" }, "locus": { "chromosome": "Z", "start_pos": 16617042, "end_pos": 16612381, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029833.1", "url": "https://www.ensembl.org/id/ENSGALT00010029833.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017373.1", "url": "https://www.ensembl.org/id/ENSGALP00010017373.1" } ] } }, { "isoform_ac": "A0A8V0YFR5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFR5/entry#A0A8V0YFR5-1", "sequence": { "sequence": "MFPVGADCKTCWGWAGNCWLRQARNGRCQVLYKTDLSKEECCKSGRLTTSWTEEDVNDNTLFKWMIFNGGAPNCIPCKETCENVDCGPGKKCKMNKKNKPRCVCAPDCSNITWKGPVCGLDGKTYRNECALLKARCKEQPELEVQYQGKCKKTCRDVLCPGSSTCVVDQTNNAYCVTCNRICPEPTSPEQYLCGNDGITYASACHLRKATCLLGRSIGLAYEGKCIKAKSCEDIQCSAGKKCLWDFKVGRGRCALCDELCPESKSDEAVCASDNTTYPSECAMKEAACSMGVLLEVKHSGSCNSINEDPEEEEEDEDQDYSFPISSILEW", "length": 330, "header": "tr|A0A8V0YFR5-1|A0A8V0YFR5_CHICK Isoform 1 of Follistatin OS=Gallus gallus OX=9031 GN=FST PE=4 SV=1 CANONICAL=A0A8V0YFR5-1" }, "locus": { "chromosome": "Z", "start_pos": 16617843, "end_pos": 16613913, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029823.1", "url": "https://www.ensembl.org/id/ENSGALT00010029823.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017366.1", "url": "https://www.ensembl.org/id/ENSGALP00010017366.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-2473224", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2473224", "resource": "Reactome", "description": "Antagonism of Activin by Follistatin" } ], "orthologs": [ { "uniprot_canonical_ac": "P19883-1", "protein_name": "Follistatin", "gene_name": "FST", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": 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"MLSAVTACSQAVTKQMPGTARHDREMAIQAKRNLSKTTDPVERLRLKCLARGSAGIKGLGKVFQIMDDDNSRTLDFKEFVKGLNDYAMMIDKEEAQEIFRIFDKDGSGTIDFDEFLVTLRPPMSNARKEIIMQAFRKLDKTGDGVITIEDLRGVYNAKHHPKYQNGDWTEDQVFRAFLDNFDSPYDKDGKVTTEEFMNYYAGVSASIDTDVYFIVMMKNAWKL", "length": 223, "header": "tr|A0A8V0YFS3-1|A0A8V0YFS3_CHICK Isoform 1 of Calcyphosine like OS=Gallus gallus OX=9031 GN=CAPSL PE=4 SV=1 CANONICAL=A0A8V0YFS3-1" }, "isoforms": [ { "isoform_ac": "A0A3Q3B0H3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFS3/entry#A0A3Q3B0H3-1", "sequence": { "sequence": "MQEMPGTARHDREMAIQAKRNLSKTTDPVERLRLKCLARGSAGIKGLGKVFQIMDDDNSRTLDFKEFVKGLNDYAMMIDKEEAQEIFRIFDKDGSGTIDFDEFLVTLRPPMSNARKEIIMQAFRKLDKTGDGVITIEDLRGVYNAKHHPKYQNGDWTEDQVFRAFLDNFDSPYDKDGKVTTEEFMNYYAGVSASIDTDVYFIVMMKNAWKL", "length": 211, "header": "tr|A0A3Q3B0H3-1|A0A3Q3B0H3_CHICK Computationally mapped isoform of Calcyphosine like OS=Gallus gallus OX=9031 GN=CAPSL PE=4 SV=1 CANONICAL=A0A8V0YFS3-1" }, "locus": { "chromosome": "Z", "start_pos": 11468661, "end_pos": 11464256, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030527.1", "url": "https://www.ensembl.org/id/ENSGALT00010030527.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017707.1", "url": "https://www.ensembl.org/id/ENSGALP00010017707.1" } ] } }, { "isoform_ac": "A0A8V0YFS3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFS3/entry#A0A8V0YFS3-1", "sequence": { "sequence": "MLSAVTACSQAVTKQMPGTARHDREMAIQAKRNLSKTTDPVERLRLKCLARGSAGIKGLGKVFQIMDDDNSRTLDFKEFVKGLNDYAMMIDKEEAQEIFRIFDKDGSGTIDFDEFLVTLRPPMSNARKEIIMQAFRKLDKTGDGVITIEDLRGVYNAKHHPKYQNGDWTEDQVFRAFLDNFDSPYDKDGKVTTEEFMNYYAGVSASIDTDVYFIVMMKNAWKL", "length": 223, "header": "tr|A0A8V0YFS3-1|A0A8V0YFS3_CHICK Isoform 1 of Calcyphosine like OS=Gallus gallus OX=9031 GN=CAPSL PE=4 SV=1 CANONICAL=A0A8V0YFS3-1" }, "locus": { "chromosome": "Z", "start_pos": 11471718, "end_pos": 11464256, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030551.1", "url": "https://www.ensembl.org/id/ENSGALT00010030551.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017723.1", "url": "https://www.ensembl.org/id/ENSGALP00010017723.1" } ] } }, { "isoform_ac": "A0A8V0YIT0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFS3/entry#A0A8V0YIT0-1", "sequence": { "sequence": "MPGTARHDREMAIQAKRNLSKTTDPVERLRLKCLARGSAGIKGLGKVFQIMDDDNSRTLDFKEFVKGLNDYAMMIDKEEAQEIFRIFDKDGSGTIDFDEFLVTLRPPMSNARKEIIMQAFRKLDKTGDGVITIEDLRGVYNAKHHPKYQNGDWTEDQVFRAFLDNFDSPYDKDGKKLEELLLFSGTKSEIQLKSRYPNR", "length": 199, "header": "tr|A0A8V0YIT0-1|A0A8V0YIT0_CHICK Computationally mapped isoform of Calcyphosine like OS=Gallus gallus OX=9031 GN=CAPSL PE=4 SV=1 CANONICAL=A0A8V0YFS3-1" }, "locus": { "chromosome": "Z", "start_pos": 11468252, "end_pos": 11465270, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030536.1", "url": "https://www.ensembl.org/id/ENSGALT00010030536.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017712.1", "url": "https://www.ensembl.org/id/ENSGALP00010017712.1" } ] } }, { "isoform_ac": "E1BV18-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFS3/entry#E1BV18-1", "sequence": { "sequence": "MPGTARHDREMAIQAKRNLSKTTDPVERLRLKCLARGSAGIKGLGKVFQIMDDDNSRTLDFKEFVKGLNDYAMMIDKEEAQEIFRIFDKDGSGTIDFDEFLVTLRPPMSNARKEIIMQAFRKLDKTGDGVITIEDLRGVYNAKHHPKYQNGDWTEDQVFRAFLDNFDSPYDKDGKVTTEEFMNYYAGVSASIDTDVYFIVMMKNAWKL", "length": 208, "header": "tr|E1BV18-1|E1BV18_CHICK Computationally mapped isoform of Calcyphosine like OS=Gallus gallus OX=9031 GN=CAPSL PE=4 SV=3 CANONICAL=A0A8V0YFS3-1" }, "locus": { "chromosome": "Z", "start_pos": 11468252, "end_pos": 11464256, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030542.1", "url": "https://www.ensembl.org/id/ENSGALT00010030542.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017716.1", "url": "https://www.ensembl.org/id/ENSGALP00010017716.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], 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"https://www.ebi.ac.uk/interpro/entry/IPR003599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013106", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013106", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050504", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050504", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR053896", "url": "https://www.ebi.ac.uk/interpro/entry/IPR053896", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YFT0", "url": "https://www.orthodb.org/?gene=A0A8V0YFT0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YFT6", "url": "https://www.orthodb.org/?gene=A0A8V0YFT6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YFU2", "url": "https://www.orthodb.org/?gene=A0A8V0YFU2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YKK7", "url": "https://www.orthodb.org/?gene=A0A8V0YKK7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YKL3", "url": "https://www.orthodb.org/?gene=A0A8V0YKL3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24100", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24100", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24100:SF151", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24100:SF151", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07686", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07686", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF22705", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22705", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-9927354", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9927354", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YFT0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFT0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YFT0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFT0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YFT6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFT6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YFT6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFT6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YFU2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFU2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YFU2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFU2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YKK7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKK7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YKK7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKK7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YKL3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKL3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YKL3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKL3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKRLGSLALRGRFGLRQPIQPQLQSPQRRSICRSIQQYSYGFLLLFLHILRAVTALEKIISKPGDNATLSCIYANRGFDLDSLRVYWQIDGVEGSKSCSVVHALISGQDNESQQCSQFKNRTQLLWDKLGDGDFSLLLYNVRQSDEHTYKCVVMQTIEYTRVIHQEQVVLSLAASYSQPILSGPIRNSYSTGEEVTFSCRSDNGYPEPNVYWINRTDNTRLSQSDFNITQHPDGTYSVLSTLKVNATSDMQLECFIENKVLQENTSANYTEEMQNNGSSTGSHKDAAKGGQGAQAAAVVSVVILMAFLTVLICWLWRRRSSQLVSYTAPV", "length": 330, "header": "tr|A0A8V0YFU2-1|A0A8V0YFU2_CHICK Isoform 1 of Inducible T-cell costimulator ligand OS=Gallus gallus OX=9031 GN=ICOSLG PE=1 SV=1 CANONICAL=A0A8V0YFU2-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YFT0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFU2/entry#A0A8V0YFT0-1", "sequence": { "sequence": "MKRLGYGFLLLFLHILRAVTALEKIISKPGDNATLSCIYANRGFDLDSLRVYWQIDGVEGSKSCSVVHALISGQDNESQQCSQFKNRTQLLWDKLGDGDFSLLLYNVRQSDEHTYKCVVMQTIEYTRVIHQEQVVLSLAASYSQPILSGPIRNSYSTGEEVTFSCRSDNGYPEPNVYWINRTDNTRLSQSDFNITQHPDGTYSVLSTLKVNATSDMQLECFIENKVLQENTSANYTEEMQNNGSSTGSHKDAAKGGQGAQAAAVVSVVILMAFLTVLICWLWRRRSSQLVSYTVV", "length": 295, "header": "tr|A0A8V0YFT0-1|A0A8V0YFU2_CHICK Computationally mapped isoform of Inducible T-cell costimulator ligand OS=Gallus gallus OX=9031 GN=ICOSLG PE=1 SV=1 CANONICAL=A0A8V0YFU2-1" }, "locus": { "chromosome": "1", "start_pos": 110471610, "end_pos": 110462108, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028834.1", "url": "https://www.ensembl.org/id/ENSGALT00010028834.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016593.1", "url": "https://www.ensembl.org/id/ENSGALP00010016593.1" } ] } }, { "isoform_ac": "A0A8V0YFT6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFU2/entry#A0A8V0YFT6-1", "sequence": { "sequence": "MKRLGYGFLLLFLHILRAVTALEKIISKPGDNATLSCIYANRGFDLDSLRVYWQIDGVEGSKSCSVVHALISGQDNESQQCSQFKNRTQLLWDKLGDGDFSLLLYNVRQSDEHTYKCVVMQTIEYTRVIHQEQVVLSLAASYSQPILSGPIRNSYSTGEEVTFSCRSDNGYPEPNVYWINRTDNTRLSQSDFNITQHPDGTYSVLSTLKVNATSDMQLECFIENKVLQENTSANYTEEMQNNGSSTGSHKDAAKGGQGAQAAAVVSVVILMAFLTVLICWLWRRRSSQLVSYTDTVFSLAHLCTICGRGAPV", "length": 312, "header": "tr|A0A8V0YFT6-1|A0A8V0YFT6_CHICK Computationally mapped isoform of Inducible T-cell costimulator ligand OS=Gallus gallus OX=9031 GN=ICOSLG PE=1 SV=1 CANONICAL=A0A8V0YFU2-1" }, "locus": { "chromosome": "1", "start_pos": 110471610, "end_pos": 110461506, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028839.1", "url": "https://www.ensembl.org/id/ENSGALT00010028839.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016598.1", "url": "https://www.ensembl.org/id/ENSGALP00010016598.1" } ] } }, { "isoform_ac": "A0A8V0YFU2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFU2/entry#A0A8V0YFU2-1", "sequence": { "sequence": "MKRLGSLALRGRFGLRQPIQPQLQSPQRRSICRSIQQYSYGFLLLFLHILRAVTALEKIISKPGDNATLSCIYANRGFDLDSLRVYWQIDGVEGSKSCSVVHALISGQDNESQQCSQFKNRTQLLWDKLGDGDFSLLLYNVRQSDEHTYKCVVMQTIEYTRVIHQEQVVLSLAASYSQPILSGPIRNSYSTGEEVTFSCRSDNGYPEPNVYWINRTDNTRLSQSDFNITQHPDGTYSVLSTLKVNATSDMQLECFIENKVLQENTSANYTEEMQNNGSSTGSHKDAAKGGQGAQAAAVVSVVILMAFLTVLICWLWRRRSSQLVSYTAPV", "length": 330, "header": "tr|A0A8V0YFU2-1|A0A8V0YFU2_CHICK Isoform 1 of Inducible T-cell costimulator ligand OS=Gallus gallus OX=9031 GN=ICOSLG PE=1 SV=1 CANONICAL=A0A8V0YFU2-1" }, "locus": { "chromosome": "1", "start_pos": 110471610, "end_pos": 110461506, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028844.1", "url": "https://www.ensembl.org/id/ENSGALT00010028844.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016603.1", "url": "https://www.ensembl.org/id/ENSGALP00010016603.1" } ] } }, { "isoform_ac": "A0A8V0YKK7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFU2/entry#A0A8V0YKK7-1", "sequence": { "sequence": "MKRLGYGFLLLFLHILRAVTALEKIISKPGDNATLSCIYANRGFDLDSLRVYWQIDGVEGSKSCSVVHALISGQDNESQQCSQFKNRTQLLWDKLGDGDFSLLLYNVRQSDEHTYKCVVMQTIEYTRVIHQEQVVLSLAASYSQPILSGPIRNSYSTGEEVTFSCRSDNGYPEPNVYWINRTDNTRLSQSDFNITQHPDGTYSVLSTLKVNATSDMQLECFIENKVLQENTSANYTEEMQNNGSSTGSHKDAAKGGQGAQAAAVVSVVILMAFLTVLICWLWRRRSSQLVSYTDAQQNEDSKKLY", "length": 305, "header": "tr|A0A8V0YKK7-1|A0A8V0YKK7_CHICK Computationally mapped isoform of Inducible T-cell costimulator ligand OS=Gallus gallus OX=9031 GN=ICOSLG PE=1 SV=1 CANONICAL=A0A8V0YFU2-1" }, "locus": { "chromosome": "1", "start_pos": 110471610, "end_pos": 110464196, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028832.1", "url": "https://www.ensembl.org/id/ENSGALT00010028832.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016591.1", "url": "https://www.ensembl.org/id/ENSGALP00010016591.1" } ] } }, { "isoform_ac": "A0A8V0YKL3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFU2/entry#A0A8V0YKL3-1", "sequence": { "sequence": "MKRLGYGFLLLFLHILRAVTALEKIISKPGDNATLSCIYANRGFDLDSLRVYWQIDGVEGSKSCSVVHALISGQDNESQQCSQFKNRTQLLWDKLGDGDFSLLLYNVRQSDEHTYKCVVMQTIEYTRVIHQEQVVLSLAASYSQPILSGPIRNSYSTGEEVTFSCRSDNGYPEPNVYWINRTDNTRLSQSDFNITQHPDGTYSVLSTLKVNATSDMQLECFIENKVLQENTSANYTEEMQNNGSSTGSHKDAAKGGQGAQAAAVVSVVILMAFLTVLICWLWRRRSSQLVSYTVQKNHSASEM", "length": 303, "header": "tr|A0A8V0YKL3-1|A0A8V0YKL3_CHICK Computationally mapped isoform of Inducible T-cell costimulator ligand OS=Gallus gallus OX=9031 GN=ICOSLG PE=1 SV=1 CANONICAL=A0A8V0YFU2-1" }, "locus": { "chromosome": "1", "start_pos": 110471610, "end_pos": 110459257, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028837.1", "url": "https://www.ensembl.org/id/ENSGALT00010028837.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016596.1", "url": "https://www.ensembl.org/id/ENSGALP00010016596.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-9927354", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9927354", "resource": "Reactome", "description": "Co-stimulation by ICOS" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFU2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFU2" } ], "pmid": "" }, { "name": "external side of plasma membrane", "id": "GO:0009897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009897", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFU2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFU2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "signaling receptor binding", "id": "GO:0005102", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005102", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFU2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFU2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "T cell receptor signaling pathway", "id": "GO:0050852", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050852", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFU2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFU2" } ], "pmid": "" }, { "name": "regulation of cytokine production", "id": "GO:0001817", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001817", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFU2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFU2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 110, "end_pos": 112, "annotation": "n_glycosylation_sequon" }, { "start_pos": 120, "end_pos": 122, "annotation": "n_glycosylation_sequon" }, { "start_pos": 214, "end_pos": 216, "annotation": "n_glycosylation_sequon" }, { "start_pos": 227, "end_pos": 229, "annotation": 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"glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 110, "end_pos": 112 }, { "start_pos": 120, "end_pos": 122 }, { "start_pos": 214, "end_pos": 216 }, { "start_pos": 227, "end_pos": 229 }, { "start_pos": 245, "end_pos": 247 }, { "start_pos": 264, "end_pos": 266 }, { "start_pos": 268, "end_pos": 270 }, { "start_pos": 276, "end_pos": 278 }, { "start_pos": 66, "end_pos": 68 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": 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"IPR004843", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004843", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029052", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029052", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041805", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041805", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045473", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045473", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YFT3", "url": "https://www.orthodb.org/?gene=A0A8V0YFT3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10340", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10340", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10340:SF24", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10340:SF24", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00149", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00149", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF19272", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19272", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YFT3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFT3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YFT3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFT3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLQTCFKLLYDSRAPPAQRDEAFPRAAGTVGTQHLGHQGVSIDQSHRGEARPCSRSSACWQHGQGAPSTADMEPPGGRAARLALGLALLCSALRAAAAAPAGPVPRSAVGQFWHISDLHLDPTYHITPDHTKVCSSSKGANASNPGPFGDFLCDSPYELILSAFTFMKDSKQQASFMIWTGDSPPHVPVEELSTKLVINIIGNMSSTIHSFFPDLQVFPALGNHDYWPQDQLPVTTSEVYNAVADFWKPWLTDEAISTFRKGGFYTQLFESNVSSEPLRIISLNTNLYYSPNHVTVNITDPANQLAWLEGILEASSQKKEKVYVIGHVPIGYLPFARNTTAIREYYNERLVKIFRKYSSVIAGQFFGHTHRDSIMVLLDEEEKPVNSLFVAPAVTPVKNVWQMESNNPGVRLYQYDPLNYSLLDLWQFYLDLRDANKKNESNWKLEYILTKAYGIEDLKPESLYEMAKQLSVPHSTLFEQYYNNFIVSYNKTIVCEEGCKTCQICAIQYLDYSSYTDCINREEAWRKHGDEVSNTIYANVNQRL", "length": 544, "header": "tr|A0A8V0YFT3-1|A0A8V0YFT3_CHICK Isoform 1 of Sphingomyelin phosphodiesterase acid like 3A OS=Gallus gallus OX=9031 GN=SMPDL3A PE=1 SV=1 CANONICAL=A0A8V0YFT3-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YFT3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFT3/entry#A0A8V0YFT3-1", "sequence": { "sequence": 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This record is derived from a genomic sequence (NC_052539.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040560735", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040560735" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFV7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFV7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RGS13", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFV7", "locus": { "chromosome": "8", "start_pos": 3604530, "end_pos": 3615044, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012783", "url": "https://www.ensembl.org/id/ENSGALG00010012783" } ] } } ], "crossref": [ { "id": "A0A8V0YFV7", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YFV7", "database": 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PE=4 SV=1 CANONICAL=A0A8V0YFV7-1" }, "locus": { "chromosome": "8", "start_pos": 3614914, "end_pos": 3606156, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030636.1", "url": "https://www.ensembl.org/id/ENSGALT00010030636.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017767.1", "url": "https://www.ensembl.org/id/ENSGALP00010017767.1" } ] } }, { "isoform_ac": "A0A8V0YNR1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFV7/entry#A0A8V0YNR1-1", "sequence": { "sequence": "MSPNTCWLCKTFRAEENGIISKVSLDEVLQWSQSFEKLIRSKHGPMIYKTYLKTEHSDENIEFWLACEAYKKITSQRKRIYVARKLFTSYIQPQAPKEINIDSPVKKSIIRNLQEPTQSCFDEAQRVVYMHMERDSYPRFLESKFYQQLKYRLRTDNNIPSVR", "length": 163, "header": "tr|A0A8V0YNR1-1|A0A8V0YNR1_CHICK Computationally mapped isoform of Regulator of G protein signaling 13 OS=Gallus gallus OX=9031 GN=RGS13 PE=4 SV=1 CANONICAL=A0A8V0YFV7-1" }, "locus": { "chromosome": "8", "start_pos": 3611023, "end_pos": 3606156, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030632.1", "url": "https://www.ensembl.org/id/ENSGALT00010030632.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017766.1", "url": "https://www.ensembl.org/id/ENSGALP00010017766.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:429059", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:429059", "resource": "KEGG Pathway" }, { "id": "R-GGA-416476", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-416476", "resource": "Reactome", "description": "G alpha (q) signalling events" }, { "id": "R-GGA-418594", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-418594", "resource": "Reactome", "description": "G alpha (i) signalling events" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3Q1N2W6-1", "protein_name": "Regulator of G protein signaling 13", "gene_name": "RGS13", "tax_id": 9913, 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gallus OX=9031 GN=CXorf57 PE=4 SV=1 CANONICAL=A0A8V0YFW3-1" }, "locus": { "chromosome": "4", "start_pos": 17277852, "end_pos": 17257019, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029930.1", "url": "https://www.ensembl.org/id/ENSGALT00010029930.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017418.1", "url": "https://www.ensembl.org/id/ENSGALP00010017418.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "negative regulation of double-strand break repair via homologous recombination", "id": "GO:2000042", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000042", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFW3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFW3" } ], "pmid": "" }, { "name": "regulation of DNA repair", "id": 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This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040552979", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040552979" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFX0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFX0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "FAM60A", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFX0", "locus": { "chromosome": "1", "start_pos": 59613839, "end_pos": 59597562, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012054", "url": "https://www.ensembl.org/id/ENSGALG00010012054" } ] } } ], "crossref": [ { "id": "A0A8V0YFX0", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YFX0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000012946", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000012946", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "418140", "url": "https://www.ncbi.nlm.nih.gov/gene/418140", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR026065", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026065", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:418140", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418140", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "TPTCEEN", "url": "https://omabrowser.org/oma/group/TPTCEEN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YFX0", "url": "https://www.orthodb.org/?gene=A0A8V0YFX0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YKP3", "url": "https://www.orthodb.org/?gene=A0A8V0YKP3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "R4GJL8", "url": "https://www.orthodb.org/?gene=R4GJL8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13422", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13422", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13422:SF12", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13422:SF12", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15396", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15396", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_040552979", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040552979", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YFX0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFX0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YFX0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFX0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YKP3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKP3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YKP3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKP3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "R4GJL8", "url": "https://www.uniprot.org/uniprotkb/R4GJL8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "R4GJL8-1", "url": "https://www.uniprot.org/uniprotkb/R4GJL8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MIQTRARRREKREVWSSQTGVPWLFCNVAGYSWDEKMFGFHKPKMYRSIEGCCICRAKSSSSRFTDSKRYEKDFQNCFGLHEARSGDICNACVLLVKRWKKLPAGSKKNWNHVVDARAGPSLKTTLKPKKMKTLSGSRIKSNQISKLQKEFKRHNSDAHSTTSSASPAQSPCYSNQSDEGSDTEMSAGSSRTPVFSFLDLTYWKRQKVCCGIIYKGRFGEVLIDTHLFKPCCSNKKSATEKPEQEGPQSPAISTQEEW", "length": 258, "header": "tr|A0A8V0YFX0-1|A0A8V0YFX0_CHICK Isoform 1 of Family with sequence similarity 60 member A OS=Gallus gallus OX=9031 GN=FAM60A PE=4 SV=1 CANONICAL=A0A8V0YFX0-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YFX0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFX0/entry#A0A8V0YFX0-1", "sequence": { "sequence": "MIQTRARRREKREVWSSQTGVPWLFCNVAGYSWDEKMFGFHKPKMYRSIEGCCICRAKSSSSRFTDSKRYEKDFQNCFGLHEARSGDICNACVLLVKRWKKLPAGSKKNWNHVVDARAGPSLKTTLKPKKMKTLSGSRIKSNQISKLQKEFKRHNSDAHSTTSSASPAQSPCYSNQSDEGSDTEMSAGSSRTPVFSFLDLTYWKRQKVCCGIIYKGRFGEVLIDTHLFKPCCSNKKSATEKPEQEGPQSPAISTQEEW", "length": 258, "header": "tr|A0A8V0YFX0-1|A0A8V0YFX0_CHICK Isoform 1 of Family with sequence similarity 60 member A OS=Gallus gallus OX=9031 GN=FAM60A PE=4 SV=1 CANONICAL=A0A8V0YFX0-1" }, "locus": { "chromosome": "1", "start_pos": 59611683, "end_pos": 59601881, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028870.1", "url": "https://www.ensembl.org/id/ENSGALT00010028870.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016629.1", "url": "https://www.ensembl.org/id/ENSGALP00010016629.1" } ] } }, { "isoform_ac": "A0A8V0YKP3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFX0/entry#A0A8V0YKP3-1", "sequence": { "sequence": "MEVCVAGYSWDEKMFGFHKPKMYRSIEGCCICRAKSSSSRFTDSKRYEKDFQNCFGLHEARSGDICNACVLLVKRWKKLPAGSKKNWNHVVDARAGPSLKTTLKPKKMKTLSGSRIKSNQISKLQKEFKRHNSDAHSTTSSASPAQSPCYSNQSDEGSDTEMSAGSSRTPVFSFLDLTYWKRQKVCCGIIYKGRFGEVLIDTHLFKPCCSNKKSATEKPEQEGPQSPAISTQEEW", "length": 235, "header": "tr|A0A8V0YKP3-1|A0A8V0YKP3_CHICK Computationally mapped isoform of Family with sequence similarity 60 member A OS=Gallus gallus OX=9031 GN=FAM60A PE=4 SV=1 CANONICAL=A0A8V0YFX0-1" }, "locus": { "chromosome": "1", "start_pos": 59611683, "end_pos": 59605209, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028868.1", "url": "https://www.ensembl.org/id/ENSGALT00010028868.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016627.1", "url": "https://www.ensembl.org/id/ENSGALP00010016627.1" } ] } }, { "isoform_ac": "R4GJL8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFX0/entry#R4GJL8-1", "sequence": { "sequence": "MFGFHKPKMYRSIEGCCICRAKSSSSRFTDSKRYEKDFQNCFGLHEARSGDICNACVLLVKRWKKLPAGSKKNWNHVVDARAGPSLKTTLKPKKMKTLSGSRIKSNQISKLQKEFKRHNSDAHSTTSSASPAQSPCYSNQSDEGSDTEMSAGSSRTPVFSFLDLTYWKRQKVCCGIIYKGRFGEVLIDTHLFKPCCSNKKSATEKPEQEGPQSPAISTQEEW", "length": 222, "header": "tr|R4GJL8-1|R4GJL8_CHICK Computationally mapped isoform of Family with sequence similarity 60 member A OS=Gallus gallus OX=9031 GN=FAM60A PE=4 SV=1 CANONICAL=A0A8V0YFX0-1" }, "locus": { "chromosome": "1", "start_pos": 59611683, "end_pos": 59605859, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028872.1", "url": "https://www.ensembl.org/id/ENSGALT00010028872.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016631.1", "url": "https://www.ensembl.org/id/ENSGALP00010016631.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:418140", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418140", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "B4F781-1", "protein_name": "SIN3-HDAC complex associated factor", "gene_name": "Sinhcaf", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFGFHKPKMYRSIEGCCICRAKSSSSRFTDSKRYEKDFQSCFGLHETRSGDICNACVLLVKRWKKLPAGSKKNWNHVVDARAGPSLKTTLKPKKVKTLSGNRMKSSQISKLQKEFKRHNSDAHSTTSSASPAQSPCYSNQSDEGSDTEMASSSNRTPVFSFLDLTYWKRQKICCGIIYKGRFGEVLIDTHLFKPCCSSKKAAAEKPEEQAPAPLPISTQEW", "length": 221 }, "evidence": [ { "id": "A0A8V0YFX0", "url": "https://omabrowser.org/oma/group/A0A8V0YFX0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8C8M1-1", "protein_name": "SIN3-HDAC complex-associated factor", "gene_name": "Sinhcaf", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFGFHKPKMYRSIEGCCICRAKSSSSRFTDSKRYEKDFQSCFGLHETRSGDICNACVLLVKRWKKLPAGSKKNWNHVVDARAGPSLKTTLKPKKVKTLSGNRMKSNQISKLQKEFKRHNSDAHSTTSSASPAQSPCYSNQSDEGSDTEMASSSNRTPVFSFLDLTYWKRQKICCGIIYKGRFGEVLIDTHLFKPCCSSKKAAAEKPEEQGPAPLPISTQEW", "length": 221 }, "evidence": [ { "id": "A0A8V0YFX0", "url": "https://omabrowser.org/oma/group/A0A8V0YFX0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9NP50-1", "protein_name": "SIN3-HDAC complex-associated factor", "gene_name": "SINHCAF", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MFGFHKPKMYRSIEGCCICRAKSSSSRFTDSKRYEKDFQSCFGLHETRSGDICNACVLLVKRWKKLPAGSKKNWNHVVDARAGPSLKTTLKPKKVKTLSGNRIKSNQISKLQKEFKRHNSDAHSTTSSASPAQSPCYSNQSDDGSDTEMASGSNRTPVFSFLDLTYWKRQKICCGIIYKGRFGEVLIDTHLFKPCCSNKKAAAEKPEEQGPEPLPISTQEW", "length": 221 }, "evidence": [ { "id": "A0A8V0YFX0", "url": "https://omabrowser.org/oma/group/A0A8V0YFX0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "positive regulation of cell population proliferation", "id": "GO:0008284", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008284", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFX0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFX0" } ], "pmid": "" }, { "name": "negative regulation of cell migration", "id": "GO:0030336", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030336", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFX0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFX0" } ], "pmid": "" }, { "name": "negative regulation of cell differentiation", "id": "GO:0045596", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045596", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFX0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFX0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "Sin3-type complex", "id": "GO:0070822", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070822", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFX0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFX0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 175, "end_pos": 177, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 175, "end_pos": 177 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YFX6-1", "uniprot_ac": "A0A8V0YFX6", "uniprot_id": "A0A8V0YFX6_CHICK", "mass": { "chemical_mass": 40261.0, "monoisotopic_mass": 40261.0 }, "refseq": {}, "gene_names": [ { "name": "TUSC3", "type": "recommended", "evidence": [ { "id": "A0A8V0YFX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFX6" } ] } ], "protein_names": [ { "name": "Tumor suppressor candidate 3", "type": "synonym", "evidence": [ { "id": "A0A8V0YFX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFX6/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFX6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFX6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TUSC3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFX6", "locus": { "chromosome": "4", "start_pos": 63136954, "end_pos": 63248925, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013958", "url": "https://www.ensembl.org/id/ENSGALG00010013958" } ] } } ], "crossref": [ { "id": "A0A8V0YFX6", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YFX6", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000013674", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000013674", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd02947", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02947", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR021149", "url": "https://www.ebi.ac.uk/interpro/entry/IPR021149", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036249", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036249", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PNP2", "url": "https://www.orthodb.org/?gene=A0A1D5PNP2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YFX6", "url": "https://www.orthodb.org/?gene=A0A8V0YFX6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YLX7", "url": "https://www.orthodb.org/?gene=A0A8V0YLX7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YU38", "url": "https://www.orthodb.org/?gene=A0A8V0YU38", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12692", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12692", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12692:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12692:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04756", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04756", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-5223345", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5223345", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9931295", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9931295", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A1D5PNP2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PNP2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PNP2-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PNP2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YFX6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFX6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YFX6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFX6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLX7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLX7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLX7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLX7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YU38", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YU38", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YU38-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YU38-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASGSRVLRRLLHLSAGNCLLLLLLLLLFLCGQLGGGQKKKEVSVIFFSIAVLLSKNLLAEKVEQLMEWSSRRSVIRMNGDKFRRFVKAPPRNYSVIVMFTALQPQRQCSVCRQANEEYQVLANSWRYSSAFSNKLFFTIVDYDEGADVFQQLNMNSAPTFMHFPPKGKPKRADTFDLQRIGFAAEQLAKWIADRTDVHIRVFRPPNYSGTIALALLVSLVGGLLYLRRNNLEFIYNKTGWAMAALCVVFAMTSGQMWNHIRGPPYAHKNPQNGQVSYIHGSSQAQFVAESHIILLLNAAITMGMVLLNEAATSKGDVGKRRIICLVGLGLVVFFFSFLLSIFRSKYHGYPYSFLIK", "length": 357, "header": "tr|A0A8V0YFX6-1|A0A8V0YFX6_CHICK Isoform 1 of Tumor suppressor candidate 3 OS=Gallus gallus OX=9031 GN=TUSC3 PE=3 SV=1 CANONICAL=A0A8V0YFX6-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PNP2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFX6/entry#A0A1D5PNP2-1", "sequence": { "sequence": "MASGSRVLRRLLHLSAGNCLLLLLLLLLFLCGQLGGGQKKKENLLAEKVEQLMEWSSRRSVIRMNGDKFRRFVKAPPRNYSVIVMFTALQPQRQCSVCRQANEEYQVLANSWRYSSAFSNKLFFTIVDYDEGADVFQQLNMNSAPTFMHFPPKGKPKRADTFDLQRIGFAAEQLAKWIADRTDVHIRVFRPPNYSGTIALALLVSLVGGLLYLRRNNLEFIYNKTGWAMAALSYIHGSSQAQFVAESHIILLLNAAITMGMVLLNEAATSKGDVGKRRIICLVGLGLVVFFFSFLLSIFRSKYHGYPYSFLIK", "length": 313, "header": "tr|A0A1D5PNP2-1|A0A1D5PNP2_CHICK Computationally mapped isoform of Tumor suppressor candidate 3 OS=Gallus gallus OX=9031 GN=TUSC3 PE=3 SV=2 CANONICAL=A0A8V0YFX6-1" }, "locus": { "chromosome": "4", "start_pos": 63248564, "end_pos": 63137227, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033468.1", "url": 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"evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFX6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFX6" } ], "pmid": "" }, { "name": "cognition", "id": "GO:0050890", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050890", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFX6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFX6" } ], "pmid": "" }, { "name": "protein N-linked glycosylation", "id": "GO:0006487", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006487", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFX6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFX6" } ], "pmid": "" }, { "name": "magnesium ion transport", "id": "GO:0015693", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015693", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFX6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFX6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "oligosaccharyltransferase complex", "id": "GO:0008250", 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"IPR043502", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043502", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR33332", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR33332", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00078", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00078", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF03372", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03372", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YFZ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFZ5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YFZ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFZ5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YH05", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH05", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YH05-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH05-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSMGTTFFHMEEFHYTPLLHMHFDEQLVEAARSPALVLMGDFNFPDICWEYNLAQKKQSRRFLECMEDNFLMQMIREPTRGAAPLDLLFTNREGLVGDVEVGGCLGQSDHNMVEFSILGGGRRGNSKTATLDFQSADFELFRRLVGRVPWGSVLESKGEQDGWLLFKQEVLKAQEQAVPLSRKMSRCGRRPAWMNRELFLRLQEKKRIYLLWKKGRATQKEYKEIVKMCREKIRKAKAQLELKLAAGVKGNKKLLYKYINSKRRTRENLHSLLDEAGNVTTEDKEKADVLNAFFTSVFKRQTGYPQVSLLPDLAALAGEQTKPPTIQEVTVRDLLLQLDCHKSMGPDEIHPRVLRELAEVIAEPLSIIYQCSLLTDDVPEDWRLANVTPIYKKGCREDPANYRPVSLTSVPGKIMEQIVLREITRHMRDNRGIRPSQHGFTKGRSCLTNLISFYVPVTRLVDEGKAVDVVYLDFSKAFDTVSHSILLQKLADRGLDRYILRWVRNWLEGRAQRVVVNGVKSSWRPVMSGVPQGSVLGPVLFNIFNIFIDDLDEGIECTLSKFADDTKLAGSVNLPDGSEALQRDLDRLDSWAEANGMGFNKTKCRVLHFGHNNPRQRYRLGAEWLEDCVEEMDLGVLIDARLNMSQQCAQVAKKANGILACIRNSVASRNREVIIPLYSALVRLHLEYCVQFWAPHCKKDIEALQRVQRRATKLVRGLEHRPYEEWLKELGLFSLEKRRLRGDLIALYNYLKGGCSELGVSLLCRVTSGRTRGNGFKLRQGRF", "length": 783, "header": "tr|A0A8V0YFZ5-1|A0A8V0YFZ5_CHICK Isoform 1 of Reverse transcriptase domain-containing protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0YFZ5-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YFZ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFZ5/entry#A0A8V0YFZ5-1", "sequence": { "sequence": "MSMGTTFFHMEEFHYTPLLHMHFDEQLVEAARSPALVLMGDFNFPDICWEYNLAQKKQSRRFLECMEDNFLMQMIREPTRGAAPLDLLFTNREGLVGDVEVGGCLGQSDHNMVEFSILGGGRRGNSKTATLDFQSADFELFRRLVGRVPWGSVLESKGEQDGWLLFKQEVLKAQEQAVPLSRKMSRCGRRPAWMNRELFLRLQEKKRIYLLWKKGRATQKEYKEIVKMCREKIRKAKAQLELKLAAGVKGNKKLLYKYINSKRRTRENLHSLLDEAGNVTTEDKEKADVLNAFFTSVFKRQTGYPQVSLLPDLAALAGEQTKPPTIQEVTVRDLLLQLDCHKSMGPDEIHPRVLRELAEVIAEPLSIIYQCSLLTDDVPEDWRLANVTPIYKKGCREDPANYRPVSLTSVPGKIMEQIVLREITRHMRDNRGIRPSQHGFTKGRSCLTNLISFYVPVTRLVDEGKAVDVVYLDFSKAFDTVSHSILLQKLADRGLDRYILRWVRNWLEGRAQRVVVNGVKSSWRPVMSGVPQGSVLGPVLFNIFNIFIDDLDEGIECTLSKFADDTKLAGSVNLPDGSEALQRDLDRLDSWAEANGMGFNKTKCRVLHFGHNNPRQRYRLGAEWLEDCVEEMDLGVLIDARLNMSQQCAQVAKKANGILACIRNSVASRNREVIIPLYSALVRLHLEYCVQFWAPHCKKDIEALQRVQRRATKLVRGLEHRPYEEWLKELGLFSLEKRRLRGDLIALYNYLKGGCSELGVSLLCRVTSGRTRGNGFKLRQGRF", "length": 783, "header": "tr|A0A8V0YFZ5-1|A0A8V0YFZ5_CHICK Isoform 1 of Reverse transcriptase domain-containing protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0YFZ5-1" }, "locus": { "chromosome": "W", "start_pos": 6536190, "end_pos": 6528690, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030712.1", "url": "https://www.ensembl.org/id/ENSGALT00010030712.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017812.1", "url": "https://www.ensembl.org/id/ENSGALP00010017812.1" } ] } }, { "isoform_ac": "A0A8V0YH05-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFZ5/entry#A0A8V0YH05-1", "sequence": { "sequence": "MSMGTTFFHMEEFHYTPLLHMHFDEQLVEAARSPALVLMGDFNFPDICWEYNLAQKKQSRRFLECMEDNFLMQMIREPTRGAAPLDLLFTNREGLVGDVEVGGCLGQSDHNMVEFSILGGGRRGNSKTATLDFQSADFELFRRLVGRVPWGSVLESKGEQDGWLLFKQEVLKAQEQAVPLSRKMSRCGRRPAWMNRELFLRLQEKKRIYLLWKKGRATQKEYKEIVKMCREKIRKAKAQLELKLAAGVKGNKKLLYKYINSKRRTRENLHSLLDEAGNVTTEDKEKADVLNAFFTSVFKRQTGYPQVSLLPDLAALAGEQTKPPTIQEVTVRDLLLQLDCHKSMGPDEIHPRVLRELAEVIAEPLSIIYQCSLLTDDVPEDWRLANVTPIYKKGCREDPANYRPVSLTSVPGKIMEQIVLREITRHMRDNRGIRPSQHGFTKGRSCLTNLISFYVPVTRLVDEGKAVDVVYLDFSKAFDTVSHSILLQKLADRGLDRYILRWVRNWLEGRAQRVVVNGVKSSWRPVMSGVPQGSVLGPVLFNIFNIFIDDLDEGIECTLSKFADDTKLAGSVNLPDGSEALQRDLDRLDSWAEANGMGFNKTKCRVLHFGHNNPRQRYRLGAEWLEDCVEEMDLGVLIDARLNMSQQCAQVAKKANSILACIRNSVVSRNREVIVPLYSALVRPHLEYCVQFWAPHCK", "length": 698, "header": "tr|A0A8V0YH05-1|A0A8V0YH05_CHICK Computationally mapped isoform of Reverse transcriptase domain-containing protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0YFZ5-1" }, "locus": { "chromosome": "W", "start_pos": 6536190, "end_pos": 6528945, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030709.1", "url": "https://www.ensembl.org/id/ENSGALT00010030709.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017810.1", "url": "https://www.ensembl.org/id/ENSGALP00010017810.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "catalytic activity", "id": "GO:0003824", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003824", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFZ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFZ5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 278, "end_pos": 280, "annotation": "n_glycosylation_sequon" }, { "start_pos": 386, "end_pos": 388, "annotation": "n_glycosylation_sequon" }, { "start_pos": 600, "end_pos": 602, "annotation": "n_glycosylation_sequon" }, { "start_pos": 643, "end_pos": 645, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YFZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFZ5" }, { "id": "PS50878", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50878" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Reverse transcriptase", "eco_id": "ECO_0000259", "start_pos": 371, "end_pos": 629, "start_aa": "Cys", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 278, "end_pos": 280 }, { "start_pos": 386, "end_pos": 388 }, { "start_pos": 600, "end_pos": 602 }, { "start_pos": 643, "end_pos": 645 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { 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gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YH13", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH13" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RHOBTB3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH13", "locus": { "chromosome": "Z", "start_pos": 58158653, "end_pos": 58203487, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012809", "url": "https://www.ensembl.org/id/ENSGALG00010012809" } ] } } ], "crossref": [ { "id": "A0A8V0YH13", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YH13", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000014675", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000014675", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd18357", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18357", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd18360", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18360", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd18532", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18532", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000210", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000210", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001806", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001806", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011333", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011333", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YAP5", "url": "https://www.orthodb.org/?gene=A0A8V0YAP5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YFZ8", "url": "https://www.orthodb.org/?gene=A0A8V0YFZ8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YH09", "url": "https://www.orthodb.org/?gene=A0A8V0YH09", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YH13", "url": "https://www.orthodb.org/?gene=A0A8V0YH13", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YNW0", "url": "https://www.orthodb.org/?gene=A0A8V0YNW0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NBA5", "url": "https://www.orthodb.org/?gene=F1NBA5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24413", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24413", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00071", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00071", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00651", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00651", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-6811440", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6811440", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9706019", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9706019", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YAP5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAP5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YAP5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAP5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YFZ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFZ8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YFZ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFZ8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YH09", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH09", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YH09-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH09-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YH13", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH13", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YH13-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH13-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YNW0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNW0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YNW0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNW0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NBA5", "url": "https://www.uniprot.org/uniprotkb/F1NBA5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NBA5-1", "url": "https://www.uniprot.org/uniprotkb/F1NBA5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSVNIVAFGNERDVLSEDSQQSSLMWSYLRRSALISEIDSSPSAEHARSAVTTEYQACVFGNVRLVVHDCPLWWCLKSSVVILLVIPKITETNMCKYAALEHRQDIFDSDWYTSRSLIGGADIIVIKYSVNDKTSFQDLKDSYVPMIKKALNHCSVPVIISAVGARKNVPCTCPLCTLDRRSCVTTSEGAQLAKEFGATYLELHALNDFYIQKYFGGVLEYFMIQSLNQKSSEKMKKRKKTQKCHRLQPPQLEQPEKMPILKGEASHYDSDLHNLLFCCQCADVAFYSEDSSKVVEAHKVILCSVSHVFMLLFDVKSPADIHDPSILRTAQSLFAVEAGAGLPTPHGVPPCSVPIRVVVKDSVFCSCLPDILHFIYSGAFQWERLEEDIKKKLKDSEKTEHVLEKVKCILKTPGKVNSLQDCQSHQIKRLYSTSLRLFFNTPVLADVIFTIQGATVPAHRAVLVARCEVMAAMFNGNFLEANSILVPVYGVSKDTFLSFLEYLYTDSCCPASILQAMSLLICAEMYQVMRLQHICELYIITQLQSMPSRELASTSLSIVSLLKKAKFHNSDCLSTWLLHFIATNYLIFSQKPEFQDLSVEERNFVEMHRWPSSMYLKQLAEYRSYIHSQRCHCTIM", "length": 636, "header": "tr|A0A8V0YH13-1|A0A8V0YH13_CHICK Isoform 1 of Rho related BTB domain containing 3 OS=Gallus gallus OX=9031 GN=RHOBTB3 PE=4 SV=1 CANONICAL=A0A8V0YH13-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YAP5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH13/entry#A0A8V0YAP5-1", "sequence": { "sequence": "MWSYLRRSALISEIDSSPSAEHARSAVTTEYQACVFGNVRLVVHDCPLWDIFDSDWYTSRSLIGGADIIVIKYSVNDKTSFQDLKDSYVPMIKKALNHCSVPVIISAVGARKNAVPCTCPLCTLDRRSCVTTSEGAQLAKEFGATYLELHALNDFYIQKYFGGVLEYFMIQSLNQKSSEKMKKRKKTQKCHRLQPPQLEQPEKMPILKGEASHYDSDLHNLLFCCQCADVAFYSEDSSKVVEAHKVILCSVSHVFMLLFDVKSPADIHDPSILRTAQSLFAVEAGAGLPTPHGVPPCSVPIRVVVKDSVFCSCLPDILHFIYSGAFQWERLEEDIKKKLKDSEKTEHVLEKVKCILKTPGKVNSLQDCQSHQIKRLYSTSLRLFFNTPVLADVIFTIQGATVPAHRAVLVARCEVMAAMFNGNFLEANSILVPVYGVSKDTFLSFLEYLYTDSCCPASILQAMSLLICAEMYQVMRLQHICELYIITQLQSMPSRELASTSLSIVSLLKKAKFHNSDCLSTWLLHFIATNYLIFSQKPEFQDLSVEERNFVEMHRWPSSMYLKQLAEYRSYIHSQRCHCTIM", "length": 582, "header": "tr|A0A8V0YAP5-1|A0A8V0YAP5_CHICK Computationally mapped isoform of Rho related BTB domain containing 3 OS=Gallus gallus OX=9031 GN=RHOBTB3 PE=4 SV=1 CANONICAL=A0A8V0YH13-1" }, "locus": { "chromosome": "Z", "start_pos": 58202925, "end_pos": 58176388, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030734.1", "url": "https://www.ensembl.org/id/ENSGALT00010030734.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017823.1", "url": "https://www.ensembl.org/id/ENSGALP00010017823.1" } ] } }, { "isoform_ac": "A0A8V0YFZ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH13/entry#A0A8V0YFZ8-1", "sequence": { "sequence": "MSVNIVAFGNERDVLSEDSQQSSLMWSYLRRSALISEIDSSPSAEHARSAVTTEYQACVFGNVRLVVHDCPLWDIFDSDWYTSRSLIGGADIIVIKYSVNDKTSFQDLKDSYVPMIKKALNHCSVPVIISAVGARKNVPCTCPLCTLDRRSCVTTSEGAQLAKEFGATYLELHALNDFYIQKYFGGVLEYFMIQSLNQKSSEKMKKRKKTQKCHRLQPPQLEQPEKMPILKGEASHYDSDLHNLLFCCQCADVAFYSEDSSKVVEAHKVILCSVSHVFMLLFDVKSPADIHDPSILRTAQSLFAVEAGAGLPTPHGVPPCSVPIRVVVKDSVFCSCLPDILHFIYSGAFQWERLEEDIKKKLKDSEKTEHVLEKVKCILKTPGKVNSLQDCQSHQIKRLYSTSLRLFFNTPVLADVIFTIQGATVPAHRAVLVARCEVMAAMFNGNFLEANSILVPVYGVSKDTFLSFLEYLYTDSCCPASILQAMSLLICAEMYQVMRLQHICELYIITQLQSMPSRELASTSLSIVSLLKKAKFHNSDCLSTWLLHFIATNYLIFSQKPEFQDLSAASVQIIER", "length": 576, "header": "tr|A0A8V0YFZ8-1|A0A8V0YH13_CHICK Computationally mapped isoform of Rho related BTB domain containing 3 OS=Gallus gallus OX=9031 GN=RHOBTB3 PE=4 SV=1 CANONICAL=A0A8V0YH13-1" }, "locus": { "chromosome": "Z", "start_pos": 58203154, "end_pos": 58177550, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030724.1", "url": "https://www.ensembl.org/id/ENSGALT00010030724.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017817.1", "url": "https://www.ensembl.org/id/ENSGALP00010017817.1" } ] } }, { "isoform_ac": "A0A8V0YH09-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH13/entry#A0A8V0YH09-1", "sequence": { "sequence": "MSVNIVAFGNERDVLSEDSQQSSLMWSYLRRSALISEIDSSPSAEHARSAVTTEYQACVFGNVRLVVHDCPLWDIFDSDWYTSRSLIGGADIIVIKYSVNDKTSFQDLKDSYVPMIKKALNHCSVPVIISAVGARKNVPCTCPLCTLDRRSCVTTSEGAQLAKEFGATYLELHALNDFYIQKYFGGVLEYFMIQSLNQKSSEKMKKRKKTQKCHRLQPPQLEQPEKMPILKGEASHYDSDLHNLLFCCQCADVAFYSEDSSKVVEAHKVILCSVSHVFMLLFDVKSPADIHDPSILRTAQSLFAVEAGAGLPTPHGVPPCSVPIRVVVKDSVFCSCLPDILHFIYSGAFQWERLEEDIKKKLKDSEKTEHVLEKVKCILKTPGKVNSLQDCQSHQIKRLYSTSLRLFFNTPVLADVIFTIQGATVPAHRAVLVARCEVMAAMFNGNFLEANSILVPVYGVSKDTFLSFLEYLYTDSCCPASILQAMSLLICAEMYQVMRLQHICELYIITQLQSMPSRELASTSLSIVSLLKKAKFHNSDCLSTWLLHFIATNYLIFSQKPEFQDLSENGEVGPPCFAWT", "length": 580, "header": "tr|A0A8V0YH09-1|A0A8V0YH09_CHICK Computationally mapped isoform of Rho related BTB domain containing 3 OS=Gallus gallus OX=9031 GN=RHOBTB3 PE=4 SV=1 CANONICAL=A0A8V0YH13-1" }, "locus": { "chromosome": "Z", "start_pos": 58203154, "end_pos": 58178901, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030722.1", "url": "https://www.ensembl.org/id/ENSGALT00010030722.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017815.1", "url": "https://www.ensembl.org/id/ENSGALP00010017815.1" } ] } }, { "isoform_ac": "A0A8V0YH13-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH13/entry#A0A8V0YH13-1", "sequence": { "sequence": "MSVNIVAFGNERDVLSEDSQQSSLMWSYLRRSALISEIDSSPSAEHARSAVTTEYQACVFGNVRLVVHDCPLWWCLKSSVVILLVIPKITETNMCKYAALEHRQDIFDSDWYTSRSLIGGADIIVIKYSVNDKTSFQDLKDSYVPMIKKALNHCSVPVIISAVGARKNVPCTCPLCTLDRRSCVTTSEGAQLAKEFGATYLELHALNDFYIQKYFGGVLEYFMIQSLNQKSSEKMKKRKKTQKCHRLQPPQLEQPEKMPILKGEASHYDSDLHNLLFCCQCADVAFYSEDSSKVVEAHKVILCSVSHVFMLLFDVKSPADIHDPSILRTAQSLFAVEAGAGLPTPHGVPPCSVPIRVVVKDSVFCSCLPDILHFIYSGAFQWERLEEDIKKKLKDSEKTEHVLEKVKCILKTPGKVNSLQDCQSHQIKRLYSTSLRLFFNTPVLADVIFTIQGATVPAHRAVLVARCEVMAAMFNGNFLEANSILVPVYGVSKDTFLSFLEYLYTDSCCPASILQAMSLLICAEMYQVMRLQHICELYIITQLQSMPSRELASTSLSIVSLLKKAKFHNSDCLSTWLLHFIATNYLIFSQKPEFQDLSVEERNFVEMHRWPSSMYLKQLAEYRSYIHSQRCHCTIM", "length": 636, "header": "tr|A0A8V0YH13-1|A0A8V0YH13_CHICK Isoform 1 of Rho related BTB domain containing 3 OS=Gallus gallus OX=9031 GN=RHOBTB3 PE=4 SV=1 CANONICAL=A0A8V0YH13-1" }, "locus": { "chromosome": "Z", "start_pos": 58203154, "end_pos": 58176388, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030728.1", "url": "https://www.ensembl.org/id/ENSGALT00010030728.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017820.1", "url": "https://www.ensembl.org/id/ENSGALP00010017820.1" } ] } }, { "isoform_ac": "A0A8V0YNW0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH13/entry#A0A8V0YNW0-1", "sequence": { "sequence": "MSVNIVAFGNERDVLSEDSQQSSLMWSYLRRSALISEIDSSPSAEHARSAVTTEYQACVFGNVRLVVHDCPLWDIFDSDWYTSRSLIGGADIIVIKYSVNDKTSFQDLKDSYVPMIKKALNHCSVPVIISAVGARKNAVPCTCPLCTLDRRSCVTTSEGAQLAKEFGATYLELHALNDFYIQKYFGGVLEYFMIQSLNQKSSEKMKKRKKTQKCHRLQPPQLEQPEKMPILKGEASHYDSDLHNLLFCCQCADVAFYSEDSSKVVEAHKVILCSVSHVFMLLFDVKSPADIHDPSILRTAQSLFAVEAGAGLPTPHGVPPCSVPIRVVVKDSVFCSCLPDILHFIYSGAFQWERLEEDIKKKLKDSEKTEHVLEKVKCILKTPGKVNSLQDCQSHQIKRLYSTSLRLFFNTPVLADVIFTIQGATVPAHRAVLVARCEVMAAMFNGNFLEANSILVPVYGVSKDTFLSFLEYLYTDSCCPASILQAMSLLICAEMYQVMRLQHICELYIITQLQSMPSRELASTSLSIVSLLKKAKFHNSDCLSTWLLHFIATNYLIFSQKPEFQDLSGVWLCLSYLQSPASGCYHHKGTKQMSGNLQLRYLRATILIPETKSKFH", "length": 616, "header": "tr|A0A8V0YNW0-1|A0A8V0YNW0_CHICK Computationally mapped isoform of Rho related BTB domain containing 3 OS=Gallus gallus OX=9031 GN=RHOBTB3 PE=4 SV=1 CANONICAL=A0A8V0YH13-1" }, "locus": { "chromosome": "Z", "start_pos": 58203154, "end_pos": 58158926, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030737.1", "url": "https://www.ensembl.org/id/ENSGALT00010030737.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017824.1", "url": "https://www.ensembl.org/id/ENSGALP00010017824.1" } ] } }, { "isoform_ac": "F1NBA5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH13/entry#F1NBA5-1", "sequence": { "sequence": "MSVNIVAFGNERDVLSEDSQQSSLMWSYLRRSALISEIDSSPSAEHARSAVTTEYQACVFGNVRLVVHDCPLWDIFDSDWYTSRSLIGGADIIVIKYSVNDKTSFQDLKDSYVPMIKKALNHCSVPVIISAVGARKNVPCTCPLCTLDRRSCVTTSEGAQLAKEFGATYLELHALNDFYIQKYFGGVLEYFMIQSLNQKSSEKMKKRKKTQKCHRLQPPQLEQPEKMPILKGEASHYDSDLHNLLFCCQCADVAFYSEDSSKVVEAHKVILCSVSHVFMLLFDVKSPADIHDPSILRTAQSLFAVEAGAGLPTPHGVPPCSVPIRVVVKDSVFCSCLPDILHFIYSGAFQWERLEEDIKKKLKDSEKTEHVLEKVKCILKTPGKVNSLQDCQSHQIKRLYSTSLRLFFNTPVLADVIFTIQGATVPAHRAVLVARCEVMAAMFNGNFLEANSILVPVYGVSKDTFLSFLEYLYTDSCCPASILQAMSLLICAEMYQVMRLQHICELYIITQLQSMPSRELASTSLSIVSLLKKAKFHNSDCLSTWLLHFIATNYLIFSQKPEFQDLSVEERNFVEMHRWPSSMYLKQLAEYRSYIHSQRCHCTIIAEHLKYTRKLSVR", "length": 618, "header": "tr|F1NBA5-1|F1NBA5_CHICK Computationally mapped isoform of Rho related BTB domain containing 3 OS=Gallus gallus OX=9031 GN=RHOBTB3 PE=4 SV=3 CANONICAL=A0A8V0YH13-1" }, "locus": { "chromosome": "Z", "start_pos": 58203154, "end_pos": 58175271, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030726.1", "url": "https://www.ensembl.org/id/ENSGALT00010030726.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017818.1", "url": "https://www.ensembl.org/id/ENSGALP00010017818.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-6811440", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6811440", "resource": "Reactome", "description": "Retrograde transport at the Trans-Golgi-Network" }, { "id": "R-GGA-9706019", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9706019", "resource": "Reactome", "description": "RHOBTB3 ATPase cycle" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 6, "go_terms": [ { "name": "GTPase activity", "id": "GO:0003924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003924", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YH13", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH13" } ], "pmid": "" }, { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YH13", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH13" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YH13", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH13" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YH13", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH13" } ], "pmid": "" }, { "name": "ubiquitin protein ligase binding", "id": "GO:0031625", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031625", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YH13", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH13" } ], "pmid": "" }, { "name": "small GTPase binding", "id": "GO:0031267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031267", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YH13", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH13" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YH13", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH13" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YH13", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH13" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "proteasome-mediated ubiquitin-dependent protein catabolic process", "id": "GO:0043161", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043161", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YH13", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH13" } ], "pmid": "" }, { "name": "regulation of proteolysis", "id": "GO:0030162", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030162", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YH13", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH13" } ], "pmid": "" }, { "name": "retrograde transport, endosome to Golgi", "id": "GO:0042147", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042147", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YH13", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH13" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YH13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH13" }, { "id": "PS50097", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50097" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "BTB", "eco_id": "ECO_0000259", "start_pos": 282, "end_pos": 384, "start_aa": "Ala", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YG17-1", "uniprot_ac": "A0A8V0YG17", "uniprot_id": "A0A8V0YG17_CHICK", "mass": { "chemical_mass": 63092.0, "monoisotopic_mass": 63092.0 }, "refseq": { "ac": "NP_001006237", "name": "ran GTPase-activating protein 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006237" }, "gene_names": [ { "name": "RANGAP1", "type": "recommended", "evidence": [ { "id": "A0A8V0YG17", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG17" } ] }, { "name": "RANGAP1", "type": "synonym", "evidence": [ { "id": "NP_001006237", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006237" } ] } ], "protein_names": [ { "name": "Ran GTPase-activating protein 1", "type": "recommended", "evidence": [ { "id": "A0A8V0YG17", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG17/entry#names_and_taxonomy" } ] }, { "name": "ran GTPase-activating protein 1", "type": "synonym", "evidence": [ { "id": "NP_001006237", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006237" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ720502.1, HAEL01007205.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000012.1. On Sep 23, 2021 this sequence version replaced NP_001006237.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001006237", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006237" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YG17", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG17" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RANGAP1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG17", "locus": { "chromosome": "1", "start_pos": 49792188, "end_pos": 49773041, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012819", "url": "https://www.ensembl.org/id/ENSGALG00010012819" } ] } } ], "crossref": [ { "id": "A0A8V0YG17", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YG17", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00116", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00116", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "417997", "url": "https://www.ncbi.nlm.nih.gov/gene/417997", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001611", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001611", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009109", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009109", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027038", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027038", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036720", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036720", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:417997", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417997", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "NGSMEAW", "url": "https://omabrowser.org/oma/group/NGSMEAW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YG12", "url": "https://www.orthodb.org/?gene=A0A8V0YG12", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YG17", "url": "https://www.orthodb.org/?gene=A0A8V0YG17", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24113", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24113", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24113:SF12", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24113:SF12", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07834", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07834", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13516", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13516", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-141430", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-141430", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-141444", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-141444", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-2467813", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2467813", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-2500257", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2500257", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-4615885", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-4615885", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-5663220", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5663220", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9615933", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9615933", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9648025", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9648025", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9793242", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9793242", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001006237", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006237", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YG12", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG12", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YG12-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG12-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YG17", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG17", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YG17-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG17-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASEDIAKLAESLAKTKVGGGQLSFKGQSLKLNTAEDAEEVIKQIEEFDGLEALRLEGNTVGVEAAKVIAKALEKKSELKRCHWSDMFTGRLRSEIPPALISLGDALITAGAQLVELDLSDNAFGPDGVRGFEALLKSPACYTLQELKLNNCGMGIGGGKILAAALKECHRKSSAQGKPLALKIFMAGRNRLENDGATALAEAFGIIGTLEEVHMPQNGINHPGITALAQAFAINSLLKVINLNDNTFTEKGAVAMAETLKALRQVEVINFGDCLVRSKGALAIADALKEGLHKLKELNLSFCEIKRDAALSVAEAIEDKVELEKLDLNGNSLGEEGCEQLQEILEGFNMATVLGSLSDDEGEEEDEEEEEEEEEEEEEEEEEEEEEEEEEQQQLKERGQGEQDSMTPKKIIGSQDSTPVPSPPVDVATFLAFPSPEKLLRLGPKCSVLIAQQTDTSDVEKVVTALLRISSVFKDEAQVKTAVHETADALMKKAFCSATFNSDAFITRLLIHMGLLKSEEKIKAVPSLYGILMTLNHMVQQDYFPKSLAPVLSAFVTKPNRALDSCSFARHMLLQTLHQL", "length": 580, "header": "tr|A0A8V0YG17-1|A0A8V0YG17_CHICK Isoform 1 of Ran GTPase-activating protein 1 OS=Gallus gallus OX=9031 GN=RANGAP1 PE=1 SV=1 CANONICAL=A0A8V0YG17-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YG12-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG17/entry#A0A8V0YG12-1", "sequence": { "sequence": "MASEDIAKLAESLAKTKVGGGQLSFKGQSLKLNTAEDAEEVIKQIEEFDGLEALRLEGNTVGVEAAKVIAKALEKKSELKRCHWSDMFTGRLRSEIPPALISLGDALITAGAQLVELDLSDNAFGPDGVRGFEALLKSPACYTLQELKLNNCGMGIGGGKILAAALKECHRKSSAQGKPLALKIFMAGRNRLENDGATALAEAFGIIGTLEEVHMPQNGINHPGITALAQAFAINSLLKVINLNDNTFTEKGAVAMAETLKALRQVEVINFGDCLVRSKGALAIADALKEGLHKLKELNLSFCEIKRDAALSVAEAIEDKVELEKLDLNGNSLGEEGCEQLQEILEGFNMATVLGSLSDDEGEEEDEEEEEEEEEEEEEEEEEEEEEEEEEQQQLKERGQGEQDSMTPKKIIGSQDSTPVPSPPVDVATFLAFPSPEKLLRLGPKCSVLIAQQTDTSDVEKVVTALLRISSVFKDEAQVKTAVHETADALMKKAFCSATFNSDAFITRLLIHMGLLKSEEKIKAVPSLYGILMTLNHMVQQDYFPKSLAPVLSAFVTK", "length": 558, "header": "tr|A0A8V0YG12-1|A0A8V0YG17_CHICK Computationally mapped isoform of Ran GTPase-activating protein 1 OS=Gallus gallus OX=9031 GN=RANGAP1 PE=1 SV=1 CANONICAL=A0A8V0YG17-1" }, "locus": { "chromosome": "1", "start_pos": 49789378, "end_pos": 49775910, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030750.1", "url": "https://www.ensembl.org/id/ENSGALT00010030750.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017832.1", "url": "https://www.ensembl.org/id/ENSGALP00010017832.1" } ] } }, { "isoform_ac": "A0A8V0YG17-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG17/entry#A0A8V0YG17-1", "sequence": { "sequence": "MASEDIAKLAESLAKTKVGGGQLSFKGQSLKLNTAEDAEEVIKQIEEFDGLEALRLEGNTVGVEAAKVIAKALEKKSELKRCHWSDMFTGRLRSEIPPALISLGDALITAGAQLVELDLSDNAFGPDGVRGFEALLKSPACYTLQELKLNNCGMGIGGGKILAAALKECHRKSSAQGKPLALKIFMAGRNRLENDGATALAEAFGIIGTLEEVHMPQNGINHPGITALAQAFAINSLLKVINLNDNTFTEKGAVAMAETLKALRQVEVINFGDCLVRSKGALAIADALKEGLHKLKELNLSFCEIKRDAALSVAEAIEDKVELEKLDLNGNSLGEEGCEQLQEILEGFNMATVLGSLSDDEGEEEDEEEEEEEEEEEEEEEEEEEEEEEEEQQQLKERGQGEQDSMTPKKIIGSQDSTPVPSPPVDVATFLAFPSPEKLLRLGPKCSVLIAQQTDTSDVEKVVTALLRISSVFKDEAQVKTAVHETADALMKKAFCSATFNSDAFITRLLIHMGLLKSEEKIKAVPSLYGILMTLNHMVQQDYFPKSLAPVLSAFVTKPNRALDSCSFARHMLLQTLHQL", "length": 580, "header": "tr|A0A8V0YG17-1|A0A8V0YG17_CHICK Isoform 1 of Ran GTPase-activating protein 1 OS=Gallus gallus OX=9031 GN=RANGAP1 PE=1 SV=1 CANONICAL=A0A8V0YG17-1" }, "locus": { "chromosome": "1", "start_pos": 49791461, "end_pos": 49775910, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030761.1", "url": "https://www.ensembl.org/id/ENSGALT00010030761.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017837.1", "url": "https://www.ensembl.org/id/ENSGALP00010017837.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:417997", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417997", "resource": "KEGG Pathway" }, { "id": "R-GGA-141430", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-141430", "resource": "Reactome", "description": "Inactivation of APC/C via direct inhibition of the APC/C complex" }, { "id": "R-GGA-141444", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-141444", "resource": "Reactome", "description": "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" }, { "id": "R-GGA-2467813", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2467813", "resource": "Reactome", "description": "Separation of Sister Chromatids" }, { "id": "R-GGA-2500257", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2500257", "resource": "Reactome", "description": "Resolution of Sister Chromatid Cohesion" }, { "id": "R-GGA-4615885", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-4615885", "resource": "Reactome", "description": "SUMOylation of DNA replication proteins" }, { "id": "R-GGA-5663220", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5663220", "resource": "Reactome", "description": "RHO GTPases Activate Formins" }, { "id": "R-GGA-9615933", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9615933", "resource": "Reactome", "description": "Postmitotic nuclear pore complex (NPC) reformation" }, { "id": "R-GGA-9648025", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9648025", "resource": "Reactome", "description": "EML4 and NUDC in mitotic spindle formation" }, { "id": "R-GGA-9793242", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9793242", "resource": "Reactome", "description": "SUMOylation of nuclear envelope proteins" } ], "orthologs": [ { "uniprot_canonical_ac": "F1MFD5-1", "protein_name": "Ran GTPase-activating protein 1", "gene_name": "RANGAP1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MASEDIAKLAETLAKTQVAGGQLSFKGKSLKLNTADDAKDVIKEIEDFDGLEALRLEGNTVGVEAARVIAKALEKKPELKRCHWSDMFTGRLRSEIPPALISLGEGLITAGAQLVELDLSDNAFGPDGVRGFEALLKSSACFTLHELKLNNCGMGIGGGKILAAALTECHRKSSAQGKPLALKVFVAGRNRLENDGATALAEAFGIIGTLEEVHMPQNGINHPGVTALAQAFAINPLLRVINLNDNTFTEKGAVAMAKTLKTLRQVEVINFGDCLVRSKGAIAIADAIHGGLPKLKELNLSFGEIKREAALSVAEAVADKTELEKLDLNGNMLGEEGCEQLQEVLEGFNMAAVLASLSDDEGEDDEDEDEEEEEEEEEEEGEEEEEDEEEEEEEEPQQEEQGEESSTPSRKGQGPNSGEPAPVLSSPPPADVSTFLAFPSPEKLLRLGPKSSMLIAQQTDTSDPEKVVSAFLKVSSVFKDEASVRTAVQDAVDALMKKAFSSSAFNSNAFLTRLLIHMGLLKSEDKIKAVANLYGPLMALTHVVQQDYFPKALAPLLLAFMTKPNGALESCSFARHNLLQTLYKV", "length": 585 }, "evidence": [ { "id": "A0A8V0YG17", "url": "https://omabrowser.org/oma/group/A0A8V0YG17/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P11745-1", "protein_name": "Ran GTPase-activating protein 1", "gene_name": "RNA1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MATLHFVPQHEEEQVYSISGKALKLTTSDDIKPYLEELAALKTCTKLDLSGNTIGTEASEALAKCIAENTQVRESLVEVNFADLYTSRLVDEVVDSLKFLLPVLLKCPHLEIVNLSDNAFGLRTIELLEDYIAHAVNIKHLILSNNGMGPFAGERIGKALFHLAQNKKAASKPFLETFICGRNRLENGSAVYLALGLKSHSEGLKVVKLYQNGIRPKGVATLIHYGLQYLKNLEILDLQDNTFTKHASLILAKALPTWKDSLFELNLNDCLLKTAGSDEVFKVFTEVKFPNLHVLKFEYNEMAQETIEVSFLPAMEKGNLPELEKLEINGNRLDEDSDALDLLQSKFDDLEVDDFEEVDSEDEEGEDEEDEDEDEKLEEIETERLEKELLEVQVDDLAERLAETEIK", "length": 407 }, "evidence": [ { "id": "A0A8V0YG17", "url": "https://omabrowser.org/oma/group/A0A8V0YG17/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P46060-1", "protein_name": "Ran GTPase-activating protein 1", "gene_name": "RANGAP1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MASEDIAKLAETLAKTQVAGGQLSFKGKSLKLNTAEDAKDVIKEIEDFDSLEALRLEGNTVGVEAARVIAKALEKKSELKRCHWSDMFTGRLRTEIPPALISLGEGLITAGAQLVELDLSDNAFGPDGVQGFEALLKSSACFTLQELKLNNCGMGIGGGKILAAALTECHRKSSAQGKPLALKVFVAGRNRLENDGATALAEAFRVIGTLEEVHMPQNGINHPGITALAQAFAVNPLLRVINLNDNTFTEKGAVAMAETLKTLRQVEVINFGDCLVRSKGAVAIADAIRGGLPKLKELNLSFCEIKRDAALAVAEAMADKAELEKLDLNGNTLGEEGCEQLQEVLEGFNMAKVLASLSDDEDEEEEEEGEEEEEEAEEEEEEDEEEEEEEEEEEEEEPQQRGQGEKSATPSRKILDPNTGEPAPVLSSPPPADVSTFLAFPSPEKLLRLGPKSSVLIAQQTDTSDPEKVVSAFLKVSSVFKDEATVRMAVQDAVDALMQKAFNSSSFNSNTFLTRLLVHMGLLKSEDKVKAIANLYGPLMALNHMVQQDYFPKALAPLLLAFVTKPNSALESCSFARHSLLQTLYKV", "length": 587 }, "evidence": [ { "id": "A0A8V0YG17", "url": "https://omabrowser.org/oma/group/A0A8V0YG17/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P46061-1", "protein_name": "Ran GTPase-activating protein 1", "gene_name": "Rangap1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASEDIAKLAETLAKTQVAGGQLSFKGKGLKLNTAEDAKDVIKEIEEFDGLEALRLEGNTVGVEAARVIAKALEKKSELKRCHWSDMFTGRLRSEIPPALISLGEGLITAGAQLVELDLSDNAFGPDGVRGFEALLKSPACFTLQELKLNNCGMGIGGGKILAAALTECHRKSSAQGKPLALKVFVAGRNRLENDGATALAEAFGIIGTLEEVHMPQNGINHPGVTALAQAFAINPLLRVINLNDNTFTEKGGVAMAETLKTLRQVEVINFGDCLVRSKGAVAIADAVRGGLPKLKELNLSFCEIKRDAALVVAEAVADKAELEKLDLNGNALGEEGCEQLQEVMDSFNMAKVLASLSDDEGEDEDEEEEGEEDDEEEEDEEDEEDDDEEEEEQEEEEEPPQRGSGEEPATPSRKILDPNSGEPAPVLSSPTPTDLSTFLSFPSPEKLLRLGPKVSVLIVQQTDTSDPEKVVSAFLKVASVFRDDASVKTAVLDAIDALMKKAFSCSSFNSNTFLTRLLIHMGLLKSEDKIKAIPSLHGPLMVLNHVVRQDYFPKALAPLLLAFVTKPNGALETCSFARHNLLQTLYNI", "length": 589 }, "evidence": [ { "id": "A0A8V0YG17", "url": "https://omabrowser.org/oma/group/A0A8V0YG17/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VIW3-1", "protein_name": "Ran GTPase-activating protein", "gene_name": "RanGAP", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSTFNFASMAAQLGQEQGISFENKVLSWNTAADVQDVVDALNKQTTVHYLNLDGNTLGVEAAKAIGEGLKRHPEFRKALWKNMFTGRLISEIPEALKHLGAALIVAGAKLTVLDLSDNALGPNGMRGLEELLRSPVCYSLQELLLCNCGLGPEGGSMLSRALIDLHANANKAGFPLQLRVFIGSRNRLEDAGATEMATAFQTLKTFEEIVLEQNSIYIEGVEALAESFKHNPHLRVLNMNDNTLKSEGAEKIAEALPFLPLLREMSFGDCLIKTNGAYHFGEALERGNERLEVIDLGFNEINSDGGLVLVNAMGNKPKLRILNLDGNSFGEEGSEKIISEMSKLPTAAALQPFQHQEEEDLEDEYQADKQDADYEEEEEVHEHANDTTEEADEDSEGDEDDEEDEGDEEYSNVAEETAYVTTNAYTTKLFNDTTNSMASETFAVANKTISQKCTPEKFCLSQKPCSQEDFDSLDMDNKLEALQSIVNQFTGDNHLLLLVFTTLKCAHLSQSSKAALDLAVSLYQATFDYAIKTKQETRVLNYVLMQLRLLPCKEVFHSDYDVKNCRFALREALKQPTFANDNIKNSFKTFLEGAES", "length": 596 }, "evidence": [ { "id": "A0A8V0YG17", "url": "https://omabrowser.org/oma/group/A0A8V0YG17/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YG17", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG17" } ], "pmid": "" }, { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YG17", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG17" } ], "pmid": "" }, { "name": "small GTPase binding", "id": "GO:0031267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031267", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YG17", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG17" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YG17", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG17" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YG17", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG17" } ], "pmid": "" }, { "name": "nuclear membrane", "id": "GO:0031965", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031965", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YG17", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG17" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YG17", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG17" } ], "pmid": "" }, { "name": "kinetochore", "id": "GO:0000776", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000776", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YG17", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG17" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YG17", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG17" } ], "pmid": "" }, { "name": "protein sumoylation", "id": "GO:0016925", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016925", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YG17", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG17" } ], "pmid": "" }, { "name": "nuclear export", "id": "GO:0051168", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051168", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YG17", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG17" } ], "pmid": "" }, { "name": "negative regulation of protein export from nucleus", "id": "GO:0046826", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046826", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YG17", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG17" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 299, "end_pos": 301, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YG17", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG17" }, { "id": "PF07834", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07834" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ran-GTPase activating protein 1 C-terminal", "eco_id": "ECO_0000259", "start_pos": 403, "end_pos": 578, "start_aa": "Gln", "end_aa": "His", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { 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"o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YG13-1", "uniprot_ac": "A0A8V0YG13", "uniprot_id": "A0A8V0YG13_CHICK", "mass": { "chemical_mass": 72350.0, "monoisotopic_mass": 72350.0 }, "refseq": {}, "gene_names": [ { "name": "CDC16", "type": "recommended", "evidence": [ { "id": "A0A8V0YG13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG13" } ] } ], "protein_names": [ { "name": "Cell division cycle 16", "type": "synonym", "evidence": [ { "id": "A0A8V0YG13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG13/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YG13", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG13" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CDC16", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG13", "locus": { "chromosome": "1", "start_pos": 136950874, "end_pos": 136972059, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010014001", "url": "https://www.ensembl.org/id/ENSGALG00010014001" } ] } } ], "crossref": [ { "id": "A0A8V0YG13", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YG13", "database": "AlphaFoldDB", "categories": [] }, { "id": "418735", "url": "https://www.ncbi.nlm.nih.gov/gene/418735", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011990", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011990", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019734", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019734", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YG13", "url": "https://www.orthodb.org/?gene=A0A8V0YG13", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YP79", "url": "https://www.orthodb.org/?gene=A0A8V0YP79", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YP88", "url": "https://www.orthodb.org/?gene=A0A8V0YP88", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YU80", "url": "https://www.orthodb.org/?gene=A0A8V0YU80", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12558", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12558", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12558:SF9", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12558:SF9", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF12895", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12895", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13424", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13424", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-141430", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-141430", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-174048", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-174048", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-174084", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-174084", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-174154", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-174154", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-174178", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-174178", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-174184", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-174184", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-176407", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-176407", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-176408", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-176408", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-176409", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-176409", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-176412", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-176412", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-179409", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-179409", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-2467813", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2467813", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-2559582", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2559582", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-68867", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-68867", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-69017", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-69017", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-983168", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983168", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YG13", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG13", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YG13-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG13-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YP79", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP79", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YP79-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP79-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YP88", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP88", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YP88-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP88-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YU80", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YU80", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YU80-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YU80-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNLERLRKRVRHYIDQQQYQSALFWADKVASLSHEEPQDIYWLAQCLYLTAQYHRAAHALRSRKLDKLYEACRYLAARCHYAAKEHQQALDILDMEEPINKRLFEKYLKDENGLKDSTTDWEMSQSSIKSSICLLRGKIYDALDNRTLATYSYKEALKLDVYCFEAFDLLTSHHMLTAQEEKELLESLPLNKQCTEEEQELLHFLFENKLKKYNKPSETLIPESVNGLQENLDVVVSLAERHYYNCDFKMCYKRTSLVMEKDPFHANCLPVHIGTLVELNKANELFYLSHKLVDLYPNNPVSWFAVGCYYLMVGHKNEHARRYLSKATTLERTYGPAWIAYGHSFAVESEHDQAMAAYFTAAQLMKGCHLPMLYIGLEYGLTNNSKLAERFFSQALSIAPEDPFVMHEVGVVAFQNGDWKTAEKWFLDALEKIKAIGNEITVDKWEPLLNNLGHVCRKLKKYEEALEYHRQALVLIPQNASTYSAIGYIHSLMGNFESAIDYFHTALGLRRDDTFSVTMLGHCIEMYIGDSEAYIGTEIKDKLRCYDFDVHTMKTLKNIISPAWDFREFDIERQTLDESSIVTLETSHQRTNTDTSRPLEETFEIEMNESDMMLETSMSDHK", "length": 622, "header": "tr|A0A8V0YG13-1|A0A8V0YG13_CHICK Isoform 1 of Cell division cycle 16 OS=Gallus gallus OX=9031 GN=CDC16 PE=4 SV=1 CANONICAL=A0A8V0YG13-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YG13-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG13/entry#A0A8V0YG13-1", "sequence": { "sequence": "MNLERLRKRVRHYIDQQQYQSALFWADKVASLSHEEPQDIYWLAQCLYLTAQYHRAAHALRSRKLDKLYEACRYLAARCHYAAKEHQQALDILDMEEPINKRLFEKYLKDENGLKDSTTDWEMSQSSIKSSICLLRGKIYDALDNRTLATYSYKEALKLDVYCFEAFDLLTSHHMLTAQEEKELLESLPLNKQCTEEEQELLHFLFENKLKKYNKPSETLIPESVNGLQENLDVVVSLAERHYYNCDFKMCYKRTSLVMEKDPFHANCLPVHIGTLVELNKANELFYLSHKLVDLYPNNPVSWFAVGCYYLMVGHKNEHARRYLSKATTLERTYGPAWIAYGHSFAVESEHDQAMAAYFTAAQLMKGCHLPMLYIGLEYGLTNNSKLAERFFSQALSIAPEDPFVMHEVGVVAFQNGDWKTAEKWFLDALEKIKAIGNEITVDKWEPLLNNLGHVCRKLKKYEEALEYHRQALVLIPQNASTYSAIGYIHSLMGNFESAIDYFHTALGLRRDDTFSVTMLGHCIEMYIGDSEAYIGTEIKDKLRCYDFDVHTMKTLKNIISPAWDFREFDIERQTLDESSIVTLETSHQRTNTDTSRPLEETFEIEMNESDMMLETSMSDHK", "length": 622, "header": "tr|A0A8V0YG13-1|A0A8V0YG13_CHICK Isoform 1 of Cell division cycle 16 OS=Gallus gallus OX=9031 GN=CDC16 PE=4 SV=1 CANONICAL=A0A8V0YG13-1" }, "locus": { "chromosome": "1", "start_pos": 136971927, "end_pos": 136952569, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033601.1", "url": 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Computationally mapped isoform of Cell division cycle 16 OS=Gallus gallus OX=9031 GN=CDC16 PE=4 SV=1 CANONICAL=A0A8V0YG13-1" }, "locus": { "chromosome": "1", "start_pos": 136971927, "end_pos": 136953065, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033581.1", "url": "https://www.ensembl.org/id/ENSGALT00010033581.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019784.1", "url": "https://www.ensembl.org/id/ENSGALP00010019784.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-141430", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-141430", "resource": "Reactome", "description": "Inactivation of APC/C via direct inhibition of the APC/C complex" }, { "id": "R-GGA-174048", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-174048", "resource": "Reactome", "description": "APC/C:Cdc20 mediated degradation of Cyclin B" }, { 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"table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YG14-1", "uniprot_ac": "A0A8V0YG14", "uniprot_id": "A0A8V0YG14_CHICK", "mass": { "chemical_mass": 46061.0, "monoisotopic_mass": 46061.0 }, "refseq": { "ac": "XP_004949094", "name": "uncharacterized protein C18orf25 homolog isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004949094" }, "gene_names": [ { "name": "CZH18ORF25", "type": "recommended", "evidence": [ { "id": "A0A8V0YG14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG14" } ] }, { "name": "CZH18ORF25", "type": "synonym", "evidence": [ { "id": "XP_004949094", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004949094" } ] } ], "protein_names": [ { "name": "E3 ubiquitin-protein ligase Arkadia N-terminal domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A8V0YG14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG14/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein C18orf25 homolog isoform X1", "type": "synonym", "evidence": [ { "id": "XP_004949094", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004949094" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052572.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jan 4, 2016 this sequence version replaced XP_004949094.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004949094", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004949094" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YG14", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG14" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CZH18ORF25", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG14", "locus": {} } ], "crossref": [ { "id": "A0A8V0YG14", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YG14", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000041081", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000041081", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "416381", "url": "https://www.ncbi.nlm.nih.gov/gene/416381", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR029306", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029306", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051073", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051073", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:416381", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416381", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PVIAHYD", "url": "https://omabrowser.org/oma/group/PVIAHYD/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5NXP4", "url": "https://www.orthodb.org/?gene=A0A1D5NXP4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q2U1Q8", "url": "https://www.orthodb.org/?gene=A0A3Q2U1Q8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YG14", "url": "https://www.orthodb.org/?gene=A0A8V0YG14", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16200", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16200", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15303", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15303", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_004949094", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004949094", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5NXP4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NXP4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5NXP4-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NXP4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2U1Q8", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U1Q8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2U1Q8-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U1Q8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YG14", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG14", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YG14-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG14-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKMEAVGKAEELLDSEVPPKASEKQETAPDEDGPIELETRTQKDSVPAASDSAVLSSMPCLLMELRRDSSESQLASAESDKPTGGRVYESDSSNHCMLSPSSSGHLADSDTLSSTEENEPCQAEAVVEEDPSGVSGAAAGRKSRRSRSESETSTMAAKKNRQSVDKQNGRVTKVKGHRSQKHKERIRLLRQKREAAARKKYNLLQDSSTSDSDLTCDSSTSSSDDDEEVSGSSKTITAEIPGSQKAFNIQKELHFRKKDGPPVVAHYDISDTNSDPEVVNVDNLLAAAVVQEHNNSLGNQDLGSTWRNRGLLDELGADAGRLDPGFLASDKPSPGNTQINEEINITSSDSEVEIVGVQEHARYVHPRGGVIQSVSSWKHGSGSQYINAQQTQSWTAVTPQQNWSSPPEVVDLTLDEDTRRKYLL", "length": 424, "header": "tr|A0A8V0YG14-1|A0A8V0YG14_CHICK Isoform 1 of E3 ubiquitin-protein ligase Arkadia N-terminal domain-containing protein OS=Gallus gallus OX=9031 GN=CZH18ORF25 PE=1 SV=1 CANONICAL=A0A8V0YG14-1" }, "isoforms": [ { "isoform_ac": "A0A1D5NXP4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG14/entry#A0A1D5NXP4-1", "sequence": { "sequence": "MKMEAVGKAEELLDSEVPPKASEKQETAPDEDGPIELETRTQKDSVPAASDSAVLSSMPCLLMELRRDSSESQLASAESDKPTGGRVYESDSSNHCMLSPSSSGHLADSDTLSSTEENEPCQAEAVVEEDPSGVSGAAAGRKSRRSRSESETSTMAAKKNRQSVDKQNGRVTKVKGHRSQKHKERIRLLRQKREAAARKKYNLLQDSSTSDSDLTCDSSTSSSDDDEEVSGSSKTITAEIPGSQKAFNIQKELHFRKKAGFSRAGGSGGATREIPGLLDRGTVWDRNCIGNVLEEAMNCFAEMQRQTEEKFRMWIEKLTRLDTDEESKQQLEPREPKMQLVGQRVPPTTQSGAFIQMPDSQVLPQQSFNSYMGCQNVDATLEFPATFNNNFPPIFPENGNIAEPDLNQS", "length": 409, "header": "tr|A0A1D5NXP4-1|A0A1D5NXP4_CHICK Computationally mapped isoform of E3 ubiquitin-protein ligase Arkadia N-terminal domain-containing protein OS=Gallus gallus OX=9031 GN=CZH18ORF25 PE=1 SV=2 CANONICAL=A0A8V0YG14-1" }, "locus": { "chromosome": "Z", "start_pos": 2447498, "end_pos": 2439988, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028908.1", "url": "https://www.ensembl.org/id/ENSGALT00010028908.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016667.1", "url": "https://www.ensembl.org/id/ENSGALP00010016667.1" } ] } }, { "isoform_ac": "A0A3Q2U1Q8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG14/entry#A0A3Q2U1Q8-1", "sequence": { "sequence": "MKMEAVGKAEELLDSEVPPKASEKQETAPDEDGPIELETRTQKDSVPAASDSAVLSSMPCLLMELRRDSSESQLASAESDKPTGGRVYESDSSNHCMLSPSSSGHLADSDTLSSTEENEPCQAEAVVEEDPSGVSGAAAGRKSRRSRSESETSTMAAKKNRQSVDKQNGRVTKVKGHRSQKHKERIRLLRQKREAAARKKYNLLQDSSTSDSDLTCDSSTSSSDDDEEVSGSSKTITAEIPAGFSRAGGSGGATREIPGLLDRGTVWDRNCIGNVLEEAMNCFAEMQRQTEEKFRMWIEKLTRLDTDEESKQQLEPREPKMQLVGQRVPPTTQSGAFIQMPDSQVLPQQSFNSYMGCQNVDATLEFPATFNNNFPPIFPENGNIAEPDLNQS", "length": 392, "header": "tr|A0A3Q2U1Q8-1|A0A3Q2U1Q8_CHICK Computationally mapped isoform of E3 ubiquitin-protein ligase Arkadia N-terminal domain-containing protein OS=Gallus gallus OX=9031 GN=CZH18ORF25 PE=1 SV=1 CANONICAL=A0A8V0YG14-1" }, "locus": { "chromosome": "Z", "start_pos": 2447498, "end_pos": 2439988, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028905.1", "url": "https://www.ensembl.org/id/ENSGALT00010028905.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016664.1", "url": "https://www.ensembl.org/id/ENSGALP00010016664.1" } ] } }, { "isoform_ac": "A0A8V0YG14-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG14/entry#A0A8V0YG14-1", "sequence": { "sequence": "MKMEAVGKAEELLDSEVPPKASEKQETAPDEDGPIELETRTQKDSVPAASDSAVLSSMPCLLMELRRDSSESQLASAESDKPTGGRVYESDSSNHCMLSPSSSGHLADSDTLSSTEENEPCQAEAVVEEDPSGVSGAAAGRKSRRSRSESETSTMAAKKNRQSVDKQNGRVTKVKGHRSQKHKERIRLLRQKREAAARKKYNLLQDSSTSDSDLTCDSSTSSSDDDEEVSGSSKTITAEIPGSQKAFNIQKELHFRKKDGPPVVAHYDISDTNSDPEVVNVDNLLAAAVVQEHNNSLGNQDLGSTWRNRGLLDELGADAGRLDPGFLASDKPSPGNTQINEEINITSSDSEVEIVGVQEHARYVHPRGGVIQSVSSWKHGSGSQYINAQQTQSWTAVTPQQNWSSPPEVVDLTLDEDTRRKYLL", "length": 424, "header": "tr|A0A8V0YG14-1|A0A8V0YG14_CHICK Isoform 1 of E3 ubiquitin-protein ligase Arkadia N-terminal domain-containing protein OS=Gallus gallus OX=9031 GN=CZH18ORF25 PE=1 SV=1 CANONICAL=A0A8V0YG14-1" }, "locus": { "chromosome": "Z", "start_pos": 2447498, "end_pos": 2422624, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028910.1", "url": "https://www.ensembl.org/id/ENSGALT00010028910.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016669.1", "url": "https://www.ensembl.org/id/ENSGALP00010016669.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 398, "start_aa": "Thr", "end_pos": 398, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr398", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:416381", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416381", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "F1RPS7-1", "protein_name": "Arkadia (RNF111) N-terminal like PKA signaling regulator 2N", "gene_name": "ARK2N", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MKMEEAVGKVEELIESEVPPKTSQQETAKEEDGSVELESQVQKDGVVDSAVLSSMPCLLMELRRDSSESQLASTESDKPTTGRVYESDSSNHCMLSPSSSGHLADSDTLSSAEENEPSQAETAVEGDPSGVSGATVGRKSRRSRSESETSTMAAKKNRQSSDKQNGRVAKVKGHRSQKHKERIRLLRQKREAAARKKYNLLQDSSTSDSDLTCDSSTSSSDDDEEVSGSSKTITAEIPDGPPVVAHYDLSDTSSEPEVVNVDNLLAAAVVQEHSNSVGGQDTGATWRTSGLLEELNAEAGHLDPGFLASDKTPAGNAPLNEEINIASSDSEVEIVGVQEHARCVHPRGGVIQSVSSWKHGSGTQYVSTRQTQSWTAVTPQQTWASPAEVVDLTLDEDSRRKYLL", "length": 404 }, "evidence": [ { "id": "A0A8V0YG14", "url": "https://omabrowser.org/oma/group/A0A8V0YG14/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q96B23-1", "protein_name": "Protein ARK2N", "gene_name": "ARK2N", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKMEEAVGKVEELIESEAPPKASEQETAKEEDGSVELESQVQKDGVADSTVISSMPCLLMELRRDSSESQLASTESDKPTTGRVYESDSSNHCMLSPSSSGHLADSDTLSSAEENEPSQAETAVEGDPSGVSGATVGRKSRRSRSESETSTMAAKKNRQSSDKQNGRVAKVKGHRSQKHKERIRLLRQKREAAARKKYNLLQDSSTSDSDLTCDSSTSSSDDDEEVSGSSKTITAEIPDGPPVVAHYDMSDTNSDPEVVNVDNLLAAAVVQEHSNSVGGQDTGATWRTSGLLEELNAEAGHLDPGFLASDKTSAGNAPLNEEINIASSDSEVEIVGVQEHARCVHPRGGVIQSVSSWKHGSGTQYVSTRQTQSWTAVTPQQTWASPAEVVDLTLDEDSRRKYLL", "length": 404 }, "evidence": [ { "id": "A0A8V0YG14", "url": "https://omabrowser.org/oma/group/A0A8V0YG14/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YG14", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG14" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YG14", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG14" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "ubiquitin-dependent protein catabolic process", "id": "GO:0006511", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006511", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YG14", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG14" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 294, "end_pos": 296, "annotation": "n_glycosylation_sequon" }, { "start_pos": 344, "end_pos": 346, "annotation": "n_glycosylation_sequon" }, { "start_pos": 402, "end_pos": 404, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YG14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG14" }, { "id": "PF15303", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15303" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "E3 ubiquitin-protein ligase Arkadia N-terminal", "eco_id": "ECO_0000259", "start_pos": 71, "end_pos": 228, "start_aa": "Glu", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 398 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 294, "end_pos": 296 }, { "start_pos": 344, "end_pos": 346 }, { "start_pos": 402, "end_pos": 404 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YG27-1", "uniprot_ac": "A0A8V0YG27", "uniprot_id": "A0A8V0YG27_CHICK", "mass": { "chemical_mass": 95225.0, "monoisotopic_mass": 95225.0 }, "refseq": {}, "gene_names": [ { "name": "PARP8", "type": "recommended", "evidence": [ { "id": "A0A8V0YG27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG27" } ] } ], "protein_names": [ { "name": "Poly [ADP-ribose] polymerase", "type": "recommended", "evidence": [ { "id": "A0A8V0YG27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG27/entry#names_and_taxonomy" } ] }, { "name": "2.4.2.-", "type": "synonym", "evidence": [ { "id": "A0A8V0YG27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG27/entry#names_and_taxonomy" } ] }, { "name": "PARP", "type": "synonym", "evidence": [ { "id": "A0A8V0YG27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG27/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Mono-ADP-ribosyltransferase that mediates mono-ADP-ribosylation of target proteins.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YG18", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG18#function" }, { "database": "UniProtKB", "id": "ARBA00055359", "url": "https://www.uniprot.org/uniprotkb/ARBA00055359#function" }, { "database": "UniProtKB", "id": "A0A8V0YG27", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG27#function" }, { "database": "UniProtKB", "id": "A0A8V0YMF6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMF6#function" }, { "database": "UniProtKB", "id": "A0A8V0YMG1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMG1#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YG27", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG27" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PARP8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG27", "locus": { "chromosome": "Z", "start_pos": 15450368, "end_pos": 15336605, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010014014", "url": "https://www.ensembl.org/id/ENSGALG00010014014" } ] } } ], "crossref": [ { "id": "A0A8V0YG27", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YG27", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd01341", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01341", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR012317", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012317", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051838", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051838", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YG18", "url": "https://www.orthodb.org/?gene=A0A8V0YG18", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YG27", "url": "https://www.orthodb.org/?gene=A0A8V0YG27", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YMF6", "url": "https://www.orthodb.org/?gene=A0A8V0YMF6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YMG1", "url": "https://www.orthodb.org/?gene=A0A8V0YMG1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21328", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21328", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00644", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00644", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YG18", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG18", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YG18-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG18-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YG27", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG27", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YG27-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG27-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YMF6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMF6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YMF6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMF6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YMG1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMG1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YMG1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMG1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGMCSRQERIQKDIDVVIQKCKAEKDCLFADFRYSDSTFTFTYIGGSKSVSYSVHVSEDYPDNTYVSSSDNDEDVLVTTEPIPVIFHQIATELRKTSDVNYCLSIKAKLQKENGEESQHNSTLEEDSEGDNDSEEFYYGGQVSYDGELHKHPQLEADLIAVREIYGPNAVSLREYGAIDDVDIDLHIDVSFLDEEIAVAWDVIRTEPIVVRLHCSLTQYLSGPVPTVDVFQISTKERFGLGHQLKKIMQTFVTQQWKNSKEKSNCTHNKKVSDKKVKSPLHIFSTLRRSPSYPPPGCGKNKSKLKSEQDGISKTHKLLRRTCSSTVKAEDVCATKSHRTFGRSLSSDPRAEQTMAIKSHKLLNRSCSAAVKQEECIALKPHKLLSRSCSGDPRCEHNSTLKPHKLLSRSYSSNLRMEELDGLKNHKLLSKTYSNAPKSSKMEPFKESNIAEGRRLSLTSGLIGILTPSSSSPSQAAQNYGAKCIPVRDRGFLVQTIEFAEQRIPVLNEYCVVCDEPHVFQNGPMLRPTVCERELCVFAFQTLGVMNEAADEIATGAQVVDLLVSMCRSALESPRKVVIFEPYPSVVDPNDPQMLAFNPRKKNYDRVMKALDSITSIREMTQAPYLEIKKQMDKQDPLAHPLLQWVISSNRSHIVKLPVNRQLKFMHTPHQFLLLSSPPAKESNFRAAKNLYGSTFAFHGSHIENWHSILRNGLVVASNTRLQLHGAMFGSGIYLSPLSSISFGYSGMNKKQQKVSAKDEPASSSKGSNTSQSQKKGQQSQFLQSRNLKCIALCEVITSSDLHKHGEIWVVPNTDHVCTRFFFVLGGRSVIQRKEIEASGRDCFGSSTGVSS", "length": 851, "header": "tr|A0A8V0YG27-1|A0A8V0YG27_CHICK Isoform 1 of Poly [ADP-ribose] polymerase OS=Gallus gallus OX=9031 GN=PARP8 PE=3 SV=1 CANONICAL=A0A8V0YG27-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YG18-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG27/entry#A0A8V0YG18-1", "sequence": { "sequence": "MGMCSRQERIQKDIDVVIQKCKAEKDCLFADFRYSDSTFTFTYIGGSKSSDNDEDVLVTTEPIPVIFHQIATELRKTSDVNYCLSIKAKLQKENGEESQHNSTLEEDSEGDNDSEEFYYGGQVSYDGELHKHPQLEADLIAVREIYGPNAVSLREYGAIDDVDIDLHIDVSFLDEEIAVAWDVIRTEPIVVRLHCSLTQYLSGPVPTVDVFQISTKERFGLGHQLKKIMQTFVTQQWKNSKEKSNCTHNKKVSDKKVKSPLHIFSTLRRSPSYPPPGCGKNKSKLKSEQDGISKTHKLLRRTCSSTVKAEDVCATKSHRTFGRSLSSDPRAEQTMAIKSHKLLNRSCSAAVKQEECIALKPHKLLSRSCSGDPRCEHNSTLKPHKLLSRSYSSNLRMEELDGLKNHKLLSKTYSNAPKSSKMEPFKESNIAEGRRLSLTSGLIGILTPSSSSPSQAAQNYGAKCIPVRDRGFLVQTIEFAEQRIPVLNEYCVVCDEPHVFQNGPMLRPTVCERELCVFAFQTLGVMNEAADEIATGAQVVDLLVSMCRSALESPRKVVIFEPYPSVVDPNDPQMLAFNPRKKNYDRVMKALDSITSIREMTQAPYLEIKKQMDKQDPLAHPLLQWVISSNRSHIVKLPVNRQLKFMHTPHQFLLLSSPPAKESNFRAAKNLYGSTFAFHGSHIENWHSILRNGLVVASNTRLQLHGAMFGSGIYLSPLSSISFGYSGMNKKQQKVSAKDEPASSSKGSNTSQSQKKGQQSQFLQSRNLKCIALCEVITSSDLHKHGEIWVVPNTDHVCTRFFFVYEDGQVGDTSINTQEPSIHKEILRVIGNQTATG", "length": 837, "header": "tr|A0A8V0YG18-1|A0A8V0YG27_CHICK Computationally mapped isoform of Poly [ADP-ribose] polymerase OS=Gallus gallus OX=9031 GN=PARP8 PE=3 SV=1 CANONICAL=A0A8V0YG27-1" }, "locus": { "chromosome": "Z", "start_pos": 15443384, "end_pos": 15337014, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033614.1", "url": "https://www.ensembl.org/id/ENSGALT00010033614.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019796.1", "url": "https://www.ensembl.org/id/ENSGALP00010019796.1" } ] } }, { "isoform_ac": "A0A8V0YG27-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG27/entry#A0A8V0YG27-1", "sequence": { "sequence": "MGMCSRQERIQKDIDVVIQKCKAEKDCLFADFRYSDSTFTFTYIGGSKSVSYSVHVSEDYPDNTYVSSSDNDEDVLVTTEPIPVIFHQIATELRKTSDVNYCLSIKAKLQKENGEESQHNSTLEEDSEGDNDSEEFYYGGQVSYDGELHKHPQLEADLIAVREIYGPNAVSLREYGAIDDVDIDLHIDVSFLDEEIAVAWDVIRTEPIVVRLHCSLTQYLSGPVPTVDVFQISTKERFGLGHQLKKIMQTFVTQQWKNSKEKSNCTHNKKVSDKKVKSPLHIFSTLRRSPSYPPPGCGKNKSKLKSEQDGISKTHKLLRRTCSSTVKAEDVCATKSHRTFGRSLSSDPRAEQTMAIKSHKLLNRSCSAAVKQEECIALKPHKLLSRSCSGDPRCEHNSTLKPHKLLSRSYSSNLRMEELDGLKNHKLLSKTYSNAPKSSKMEPFKESNIAEGRRLSLTSGLIGILTPSSSSPSQAAQNYGAKCIPVRDRGFLVQTIEFAEQRIPVLNEYCVVCDEPHVFQNGPMLRPTVCERELCVFAFQTLGVMNEAADEIATGAQVVDLLVSMCRSALESPRKVVIFEPYPSVVDPNDPQMLAFNPRKKNYDRVMKALDSITSIREMTQAPYLEIKKQMDKQDPLAHPLLQWVISSNRSHIVKLPVNRQLKFMHTPHQFLLLSSPPAKESNFRAAKNLYGSTFAFHGSHIENWHSILRNGLVVASNTRLQLHGAMFGSGIYLSPLSSISFGYSGMNKKQQKVSAKDEPASSSKGSNTSQSQKKGQQSQFLQSRNLKCIALCEVITSSDLHKHGEIWVVPNTDHVCTRFFFVLGGRSVIQRKEIEASGRDCFGSSTGVSS", "length": 851, "header": "tr|A0A8V0YG27-1|A0A8V0YG27_CHICK Isoform 1 of Poly [ADP-ribose] polymerase OS=Gallus gallus OX=9031 GN=PARP8 PE=3 SV=1 CANONICAL=A0A8V0YG27-1" }, "locus": { "chromosome": "Z", "start_pos": 15450368, "end_pos": 15337014, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033638.1", "url": "https://www.ensembl.org/id/ENSGALT00010033638.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019807.1", "url": "https://www.ensembl.org/id/ENSGALP00010019807.1" } ] } }, { "isoform_ac": "A0A8V0YMF6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG27/entry#A0A8V0YMF6-1", "sequence": { "sequence": "MGMCSRQERIQKDIDVVIQKCKAEKDCLFADFRYSDSTFTFTYIGGSKSVSYSVHVSEDYPDNTYVSSSDNDEDVLVTTEPIPVIFHQIATELRKTSDVNYCLSIKAKLQKENGEESQHNSTLEEDSEGDNDSEEFYYGGQVSYDGELHKHPQLEADLIAVREIYGPNAVSLREYGAIDDVDIDLHIDVSFLDEEIAVAWDVIRTEPIVVRLHCSLTQYLSGPVPTVDVFQISTKERFGLGHQLKKIMQTFVTQQWKNSKEKSNCTHNKKVSDKKVKSPLHIFSTLRRSPSYPPPGCGKNKSKLKSEQDGISKTHKLLRRTCSSTVKAEDVCATKSHRTFGRSLSSDPRAEQTMAIKSHKLLNRSCSAAVKQEECIALKPHKLLSRSCSGDPRCEHNSTLKPHKLLSRSYSSNLRMEELDGLKNHKLLSKTYSNAPKSSKMEPFKESNIAEGRRLSLTSGLIGILTPSSSSPSQAAQNYGAKCIPVRDRGFLVQTIEFAEQRIPVLNEYCVVCDEPHVFQNGPMLRVVDLLVSMCRSALESPRKVVIFEPYPSVVDPNDPQMLAFNPRKKNYDRVMKALDSITSIREMTQAPYLEIKKQMDKQDPLAHPLLQWVISSNRSHIVKLPVNRQLKFMHTPHQFLLLSSPPAKESNFRAAKNLYGSTFAFHGSHIENWHSILRNGLVVASNTRLQLHGAMFGSGIYLSPLSSISFGYSGMNKKQQKVSAKDEPASSSKGSNTSQSQKKGQQSQFLQSRNLKCIALCEVITSSDLHKHGEIWVVPNTDHVCTRFFFVYEDGQVGDTSINTQEPSIHKEILRVIGNQTATG", "length": 825, "header": "tr|A0A8V0YMF6-1|A0A8V0YMF6_CHICK Computationally mapped isoform of Poly [ADP-ribose] polymerase OS=Gallus gallus OX=9031 GN=PARP8 PE=3 SV=1 CANONICAL=A0A8V0YG27-1" }, "locus": { "chromosome": "Z", "start_pos": 15443384, "end_pos": 15337014, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033621.1", "url": "https://www.ensembl.org/id/ENSGALT00010033621.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019798.1", "url": "https://www.ensembl.org/id/ENSGALP00010019798.1" } ] } }, { "isoform_ac": "A0A8V0YMG1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG27/entry#A0A8V0YMG1-1", "sequence": { "sequence": "MGMCSRQERIQKDIDVVIQKCKAEKDCLFADFRYSDSTFTFTYIGGSKSVSYSVHVSEDYPDNTYVSSSDNDEDVLVTTEPIPVIFHQIATELRKTSDVNYCLSIKAKLQKENGEESQHNSTLEEDSEGDNDSEEFYYGGQVSYDGELHKHPQLEADLIAVREIYGPNAVSLREYGAIDDVDIDLHIDVSFLDEEIAVAWDVIRTEPIVVRLHCSLTQYLSGPVPTVDVFQISTKERFGLGHQLKKIMQTFVTQQWKNSKEKSNCTHNKKVSDKKVKSPLHIFSTLRRSPSYPPPGCGKNKSKLKSEQDGISKTHKLLRRTCSSTVKAEDVCATKSHRTFGRSLSSDPRAEQTMAIKSHKLLNRSCSAAVKQEECIALKPHKLLSRSCSGDPRCEHNSTLKPHKLLSRSYSSNLRMEELDGLKNHKLLSKTYSNAPKSSKMEPFKESNIAEGRRLSLTSGLIGILTPSSSSPSQAAQNYGAKCIPVRDRGFLVQTIEFAEQRIPVLNEYCVVCDEPHVFQNGPMLRPTVCERELCVFAFQTLGVMNEAADEIATGAQVVDLLVSMCRSALESPRKVVIFEPYPSVVDPNDPQMLAFNPRKKNYDRVMKALDSITSIREMTQAPYLEIKKQMDKQDPLAHPLLQWVISSNRSHIVKLPVNRQLKFMHTPHQFLLLSSPPAKESNFRAAKNLYGSTFAFHGSHIENWHSILRNGLVVASNTRLQLHGAMFGSGIYLSPLSSISFGYSGMNKKQQKVSAKDEPASSSKGSNTSQSQKKGQQSQFLQSRNLKCIALCEVITSSDLHKHGEIWVVPNTDHLRRWSSG", "length": 822, "header": "tr|A0A8V0YMG1-1|A0A8V0YMG1_CHICK Computationally mapped isoform of Poly [ADP-ribose] polymerase OS=Gallus gallus OX=9031 GN=PARP8 PE=3 SV=1 CANONICAL=A0A8V0YG27-1" }, "locus": { "chromosome": "Z", "start_pos": 15443305, "end_pos": 15337014, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033629.1", "url": "https://www.ensembl.org/id/ENSGALT00010033629.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019803.1", "url": "https://www.ensembl.org/id/ENSGALP00010019803.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "nucleotidyltransferase activity", "id": "GO:0016779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016779", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YG27", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG27" } ], "pmid": "" }, { "name": "NAD+ poly-ADP-ribosyltransferase activity", "id": "GO:0003950", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003950", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YG27", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG27" } ], "pmid": "" }, { "name": "NAD+-protein mono-ADP-ribosyltransferase activity", "id": "GO:1990404", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990404", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YG27", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG27" } ], "pmid": "" }, { "name": "kinase binding", "id": "GO:0019900", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019900", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YG27", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG27" } ], "pmid": "" }, { "name": "protein serine/threonine kinase activator activity", "id": "GO:0043539", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043539", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YG27", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG27" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "protein auto-ADP-ribosylation", "id": "GO:0070213", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070213", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YG27", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG27" } ], "pmid": "" }, { "name": "endoplasmic reticulum unfolded protein response", "id": "GO:0030968", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030968", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YG27", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG27" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nuclear envelope", "id": "GO:0005635", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005635", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YG27", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG27" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YG27", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG27" } ], "pmid": "" }, { "name": "endoplasmic reticulum tubular network", "id": "GO:0071782", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071782", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YG27", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG27" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 120, "end_pos": 122, "annotation": "n_glycosylation_sequon" }, { "start_pos": 131, "end_pos": 133, "annotation": "n_glycosylation_sequon" }, { "start_pos": 264, "end_pos": 266, "annotation": "n_glycosylation_sequon" }, { "start_pos": 300, "end_pos": 302, "annotation": "n_glycosylation_sequon" }, { "start_pos": 363, "end_pos": 365, "annotation": "n_glycosylation_sequon" }, { "start_pos": 397, "end_pos": 399, "annotation": "n_glycosylation_sequon" }, { "start_pos": 649, "end_pos": 651, "annotation": "n_glycosylation_sequon" }, { "start_pos": 768, "end_pos": 770, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YG27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG27" }, { "id": "PS51059", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51059" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PARP catalytic", "eco_id": "ECO_0000259", "start_pos": 618, "end_pos": 846, "start_aa": "Glu", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 120, "end_pos": 122 }, { "start_pos": 131, "end_pos": 133 }, { "start_pos": 264, "end_pos": 266 }, { "start_pos": 300, "end_pos": 302 }, { "start_pos": 363, "end_pos": 365 }, { "start_pos": 397, "end_pos": 399 }, { "start_pos": 649, "end_pos": 651 }, { "start_pos": 768, "end_pos": 770 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YG24-1", "uniprot_ac": "A0A8V0YG24", "uniprot_id": "A0A8V0YG24_CHICK", "mass": { "chemical_mass": 79692.0, "monoisotopic_mass": 79692.0 }, "refseq": { "ac": "NP_001239205", "name": "chondroadherin-like protein precursor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001239205" }, "gene_names": [ { "name": "CHADL", "type": "recommended", "evidence": [ { "id": "A0A8V0YG24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG24" } ] }, { "name": "CHADL", "type": "synonym", "evidence": [ { "id": "NP_001239205", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001239205" } ] } ], "protein_names": [ { "name": "Chondroadherin-like protein", "type": "recommended", "evidence": [ { "id": "A0A8V0YG24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG24/entry#names_and_taxonomy" } ] }, { "name": "chondroadherin-like protein precursor", "type": "synonym", "evidence": [ { "id": "NP_001239205", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001239205" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: SRR13267655.104497.1, SRR13267654.260364.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000012.1. On Dec 3, 2021 this sequence version replaced NP_001239205.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001239205", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001239205" } ] }, { "annotation": "Potential negative modulator of chondrocyte differentiation. Inhibits collagen fibrillogenesis in vitro. May influence chondrocyte's differentiation by acting on its cellular collagenous microenvironment.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YG24", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG24#function" }, { "database": "UniProtKB", "id": "ARBA00053126", "url": "https://www.uniprot.org/uniprotkb/ARBA00053126#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YG24", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG24" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CHADL", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG24", "locus": { "chromosome": "1", "start_pos": 49797836, "end_pos": 49792660, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012832", "url": "https://www.ensembl.org/id/ENSGALG00010012832" } ] } } ], "crossref": [ { "id": "A0A8V0YG24", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YG24", "database": "AlphaFoldDB", "categories": [] }, { "id": "417998", "url": "https://www.ncbi.nlm.nih.gov/gene/417998", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000372", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000372", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000483", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000483", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001611", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001611", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003591", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003591", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050541", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050541", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:417998", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417998", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "EAQHATC", "url": "https://omabrowser.org/oma/group/EAQHATC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YG24", "url": "https://www.orthodb.org/?gene=A0A8V0YG24", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24369", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24369", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24369:SF210", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24369:SF210", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01463", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01463", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13855", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13855", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001239205", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001239205", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YG24", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG24", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YG24-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG24-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGLLLLALALALAPGGTAAAPCPAVCVCDNLRAHVLCLNRNLTAVPDTIPELTKQLNLRGNSFKALTAGAFLSTPYLTHLDLRNCQLERVEEGAFRGLGRLLHLNLASNSITVLYQEALDGLSSLQQLVLRQNNLEEMQPGAFSRLESLTLLDLRENALVYLPDMVFQGLQSLKWLRLSHNALHVLGNEAFTALPALRRLSLDHNELQALPSEALAQLSEVTRLELGHNPITYLAEEAVAMASLQHLSLEHAALQDVTPDAFSRSPLLRTLDLAHNQLRGLPALVGVGGLVRISLDGNPLLCSCLLLPFHRWMGRARVQAEGTCVAPPALQGRPLDSLRPSEMKCGQPQAPGLNPTVPSVQTGGTTTGPCPTGCTCSPEFHHTNCENRGLRKIPRGFPTDTQLLDLRRNALGMVPAGAFLGLKSLVSLHLQSCGITELRPGALRGLPNLVYLYLSDNHLSSLVPSAFEGVPRLAYLHLDHNAFTQVPSGAFQLLPNLFSLHLQHNAIRELAKGDLAGLAGLRCLSLAGNAIRSIGPAAMAATKMLEKLHLERNSLEEVPTASLRHLPALSELKLSRNPIKHIRDGAFLPVAGSLQHLYLDNMGLEQISPRAFAGLGPKIKSLHLENNKMSNIPDMKNFTGLEILNLRDVPFHCDCRLLPLYRWIEKLNLRIGATCASPVEAQGQKVKFSTTFQNCPGWRARGASADKAKAARKPSKKKRSEKPPSRGFRKSKA", "length": 733, "header": "tr|A0A8V0YG24-1|A0A8V0YG24_CHICK Isoform 1 of Chondroadherin-like protein OS=Gallus gallus OX=9031 GN=CHADL PE=3 SV=1 CANONICAL=A0A8V0YG24-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YG24-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG24/entry#A0A8V0YG24-1", "sequence": { "sequence": "MGLLLLALALALAPGGTAAAPCPAVCVCDNLRAHVLCLNRNLTAVPDTIPELTKQLNLRGNSFKALTAGAFLSTPYLTHLDLRNCQLERVEEGAFRGLGRLLHLNLASNSITVLYQEALDGLSSLQQLVLRQNNLEEMQPGAFSRLESLTLLDLRENALVYLPDMVFQGLQSLKWLRLSHNALHVLGNEAFTALPALRRLSLDHNELQALPSEALAQLSEVTRLELGHNPITYLAEEAVAMASLQHLSLEHAALQDVTPDAFSRSPLLRTLDLAHNQLRGLPALVGVGGLVRISLDGNPLLCSCLLLPFHRWMGRARVQAEGTCVAPPALQGRPLDSLRPSEMKCGQPQAPGLNPTVPSVQTGGTTTGPCPTGCTCSPEFHHTNCENRGLRKIPRGFPTDTQLLDLRRNALGMVPAGAFLGLKSLVSLHLQSCGITELRPGALRGLPNLVYLYLSDNHLSSLVPSAFEGVPRLAYLHLDHNAFTQVPSGAFQLLPNLFSLHLQHNAIRELAKGDLAGLAGLRCLSLAGNAIRSIGPAAMAATKMLEKLHLERNSLEEVPTASLRHLPALSELKLSRNPIKHIRDGAFLPVAGSLQHLYLDNMGLEQISPRAFAGLGPKIKSLHLENNKMSNIPDMKNFTGLEILNLRDVPFHCDCRLLPLYRWIEKLNLRIGATCASPVEAQGQKVKFSTTFQNCPGWRARGASADKAKAARKPSKKKRSEKPPSRGFRKSKA", "length": 733, "header": "tr|A0A8V0YG24-1|A0A8V0YG24_CHICK Isoform 1 of Chondroadherin-like protein OS=Gallus gallus OX=9031 GN=CHADL PE=3 SV=1 CANONICAL=A0A8V0YG24-1" }, "locus": { "chromosome": "1", "start_pos": 49796419, "end_pos": 49793307, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030772.1", "url": "https://www.ensembl.org/id/ENSGALT00010030772.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017847.1", "url": "https://www.ensembl.org/id/ENSGALP00010017847.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:417998", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417998", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "E9Q7T7-1", "protein_name": "Chondroadherin-like protein", "gene_name": "Chadl", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MERPQSSIWVFMLLLFMVLLQSPAWHVAAQRCPQTCVCDNSRRHVTCRHQNLTEVPNTIPELTQRLDLQGNILKVLPAAAFQDLPHLTHLDLRNCQVEMVAEGAFRGLGRLLLLNLASNRLSTLPQEALDGLGSLRRLELEGNMLEELRPGTFGALGSLTTLNLAHNALVYLPAMAFQGLLRTRWLQLSHNALSVLAPEALAGLPALRRLSLHHNELQALPGAALSQARSLARLELGHNPLTYTGEEDGLALPGLRELALDHGSLQALGPRAFAHCPRLHTLDLRGNQLTTLPPLQVPGQLRRLRLQGNPLWCACHARPLLEWLVRARVRSDGACRGPRRLRGEALDTLRPSDLRCPGDAAAGDGDGDEDEDRPAGPRAPPLRSPHGEAAWATPCPPACACVAETRHSTCDGRGLQAVPRGFPNDTQLLDLRRNHFPSVPRAAFPGLRHLVSLHLQHCGVAELEPGALAGLDRLLYLYLSHNQLSGLSAAALEGAPNLGYLYLEHNRFLRIPGTALRALPTLVSLHLQDNAVDRLAPGDLAGARALRCLYLSGNHITQVSPGALGPARELEKLHLDRNRLREVPTGALEGLPALKELQLSGNPLRALPDGAFQPVGRSLQQLFLNSSDLEQISPRAFSGLGKGLRSLYLHKNQLQSLPAPLGLSGLELVDLSGNPFHCDCQLLPLHRWLTGLNLRVGATCATPPSVRGQKVKVAAPVFEACPGWTARKAKRTPTSRGSARRTPSLSRH", "length": 748 }, "evidence": [ { "id": "A0A8V0YG24", "url": "https://omabrowser.org/oma/group/A0A8V0YG24/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F1LVK3-1", "protein_name": "Chondroadherin-like protein", "gene_name": "Chadl", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MERPQSFTLLLLMMFLSPAWNVAAQRCPQTCVCDNSRRHVTCQHQNLTEVPDTIPELTQRLDLQGNMLKVIPPAAFQDLPYLTHLDLQHCQVEQVAEGAFRGLGRLLFLNLASNRLSSLPQEALDGLGSLRRLELERNMLEELRPGTFGALGSLATLNLAHNALVYLPAMAFQGLMRTRWLQLSHNALSVLAPEALAGLPVLRRLSLHHNELQALPGAALSQARSLARLELGHNPLTYTGEEDGLALPGLRELALDHGSLQALGPRAFAHCPRLHTLDLRGNQLTTLPPLQVPGQLRRLRLQGNPLWCACHARPLLEWLVRARVRSDGACRGPRRLRGETLDTLRPSDLRCPGDAAEDEDEDRPAGPRSPPRSLHEEARWATPCPPACVCVGETRHSACDGRGLQAVPRGFPNDTQLLDLRRNHFPSVPRAAFPGLRHLVSLHLQHCGIAELEPGALAGLDGLVYLYLSNNQLSGLSAAALEGAPNLGYLYLEHNRFLRIPGAALRALPRLFSLHLQDNAVDRLAPGDLAGARALRGLYLSGNHITQVSPGALGPARELEKLHLDRNQLRQVPTGALEGLPALKELQLSRNPFRALHDGAFQPVGRSLQQLFLNSSDLEQISPRAFSGLGKGLQGLYLQQNQLQSLPAPMWLSGLELIDLSGNPFHCDCQLLPLHRWLTGLNLRVGATCATPPSVRGQKVKAAASVFEACPGWIARKAKRTPTSGVSARRTPIHGWH", "length": 737 }, "evidence": [ { "id": "A0A8V0YG24", "url": "https://omabrowser.org/oma/group/A0A8V0YG24/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6NUI6-1", "protein_name": "Chondroadherin-like protein", "gene_name": "CHADL", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEGPRSSTHVPLVLPLLVLLLLAPARQAAAQRCPQACICDNSRRHVACRYQNLTEVPDAIPELTQRLDLQGNLLKVIPAAAFQGVPHLTHLDLRHCEVELVAEGAFRGLGRLLLLNLASNHLRELPQEALDGLGSLRRLELEGNALEELRPGTFGALGALATLNLAHNALVYLPAMAFQGLLRVRWLRLSHNALSVLAPEALAGLPALRRLSLHHNELQALPGPVLSQARGLARLELGHNPLTYAGEEDGLALPGLRELLLDGGALQALGPRAFAHCPRLHTLDLRGNQLDTLPPLQGPGQLRRLRLQGNPLWCGCQARPLLEWLARARVRSDGACQGPRRLRGEALDALRPWDLRCPGDAAQEEEELEERAVAGPRAPPRGPPRGPGEERAVAPCPRACVCVPESRHSSCEGCGLQAVPRGFPSDTQLLDLRRNHFPSVPRAAFPGLGHLVSLHLQHCGIAELEAGALAGLGRLIYLYLSDNQLAGLSAAALEGAPRLGYLYLERNRFLQVPGAALRALPSLFSLHLQDNAVDRLAPGDLGRTRALRWVYLSGNRITEVSLGALGPARELEKLHLDRNQLREVPTGALEGLPALLELQLSGNPLRALRDGAFQPVGRSLQHLFLNSSGLEQICPGAFSGLGPGLQSLHLQKNQLRALPALPSLSQLELIDLSSNPFHCDCQLLPLHRWLTGLNLRVGATCATPPNARGQRVKAAAAVFEDCPGWAARKAKRTPASRPSARRTPIKGRQCGADKVGKEKGRL", "length": 762 }, "evidence": [ { "id": "A0A8V0YG24", "url": "https://omabrowser.org/oma/group/A0A8V0YG24/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "extracellular matrix", "id": "GO:0031012", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031012", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YG24", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG24" } ], "pmid": "" }, { "name": "gel phase of interstitial matrix", "id": "GO:0140150", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140150", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YG24", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG24" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "collagen binding", "id": "GO:0005518", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005518", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YG24", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG24" } ], "pmid": "" }, { "name": "collagen fibril binding", "id": "GO:0098633", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098633", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YG24", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG24" } ], "pmid": "" }, { "name": "signaling receptor activity", "id": "GO:0038023", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038023", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YG24", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG24" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "negative regulation of chondrocyte differentiation", "id": "GO:0032331", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032331", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YG24", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG24" } ], "pmid": "" }, { "name": "negative regulation of collagen fibril organization", "id": "GO:1904027", "url": 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}, { "evidence": [ { "id": "A0A8V0YG24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG24" }, { "id": "SM00013", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00013" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "LRRNT", "eco_id": "ECO_0000259", "start_pos": 21, "end_pos": 55, "start_aa": "Pro", "end_aa": "Gln", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 41, "end_pos": 43 }, { "start_pos": 637, "end_pos": 639 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": 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"database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YAS6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAS6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YAS6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAS6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YG29", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG29", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YG29-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG29-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YH48", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH48", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YH48-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH48-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTDVEPLVTDFAASGRAGRRNALPDILGSPAGAGTSDLPHKLAELSVSEGNEGAEGGEVSSSKALLESQEAEGKSNNS", "length": 78, "header": "tr|A0A8V0YH48-1|A0A8V0YH48_CHICK Isoform 1 of Protein kinase (cAMP-dependent, catalytic) inhibitor beta OS=Gallus gallus OX=9031 GN=PKIB PE=3 SV=1 CANONICAL=A0A8V0YH48-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YAS6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH48/entry#A0A8V0YAS6-1", "sequence": { "sequence": "MTDVEPLVTDFAASGRAGRRNALPDILGSPAGAGTSDLPHKLAELSVSEGSTCVFQKRASAHSHPLLSP", "length": 69, "header": "tr|A0A8V0YAS6-1|A0A8V0YAS6_CHICK Computationally mapped isoform of Protein kinase (cAMP-dependent, catalytic) inhibitor beta OS=Gallus gallus OX=9031 GN=PKIB PE=3 SV=1 CANONICAL=A0A8V0YH48-1" }, "locus": { "chromosome": "3", "start_pos": 60879536, "end_pos": 60879330, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030787.1", "url": "https://www.ensembl.org/id/ENSGALT00010030787.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017858.1", "url": "https://www.ensembl.org/id/ENSGALP00010017858.1" } ] } }, { "isoform_ac": "A0A8V0YG29-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH48/entry#A0A8V0YG29-1", "sequence": { "sequence": "MTDVEPLVTDFAASGRAGRRNALPDILGSPAGAGTSDLPHKLAELSVSEGSTCVFQKRASAHSHPLLS", "length": 68, "header": "tr|A0A8V0YG29-1|A0A8V0YH48_CHICK Computationally mapped isoform of Protein kinase (cAMP-dependent, catalytic) inhibitor beta OS=Gallus gallus OX=9031 GN=PKIB PE=3 SV=1 CANONICAL=A0A8V0YH48-1" }, "locus": { "chromosome": "3", "start_pos": 60884239, "end_pos": 60884036, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030782.1", "url": "https://www.ensembl.org/id/ENSGALT00010030782.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017852.1", "url": "https://www.ensembl.org/id/ENSGALP00010017852.1" } ] } }, { "isoform_ac": "A0A8V0YH48-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH48/entry#A0A8V0YH48-1", "sequence": { "sequence": "MTDVEPLVTDFAASGRAGRRNALPDILGSPAGAGTSDLPHKLAELSVSEGNEGAEGGEVSSSKALLESQEAEGKSNNS", "length": 78, "header": "tr|A0A8V0YH48-1|A0A8V0YH48_CHICK Isoform 1 of Protein kinase (cAMP-dependent, catalytic) inhibitor beta OS=Gallus gallus OX=9031 GN=PKIB PE=3 SV=1 CANONICAL=A0A8V0YH48-1" }, "locus": { "chromosome": "3", "start_pos": 60884239, "end_pos": 60879481, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030784.1", "url": "https://www.ensembl.org/id/ENSGALT00010030784.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017855.1", "url": "https://www.ensembl.org/id/ENSGALP00010017855.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A9J7FBB8-1", "protein_name": "cAMP-dependent protein kinase inhibitor beta isoform X1", "gene_name": "Pkib", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MDKNLDDLGGQKETSDSSKGSDSPGSQQDAVMRTDSSEMTDVESVISTFAASARAGRRNALADIQTLDVTGGTSDLPLKLEALTVKEDVKKKNEEKAQDQPEKTLNEEK", "length": 109 }, "evidence": [ { "id": "A0A8V0YH48", "url": "https://omabrowser.org/oma/group/A0A8V0YH48/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "F1SF58-1", "protein_name": "cAMP-dependent protein kinase inhibitor", "gene_name": "PKIB", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRTDSSKMTDVEPVVNNFASSARAGRRNALPDIQGSPTTGGTSELPLKLEALSVKEDVKNKDEETAQDQSEKPEDEGK", "length": 78 }, "evidence": [ { "id": "A0A8V0YH48", "url": "https://omabrowser.org/oma/group/A0A8V0YH48/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P27775-1", "protein_name": "cAMP-dependent protein kinase inhibitor beta", "gene_name": "Pkib", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTDVESVISSFASSARAGRRNALPDIQSSLATGGSPDLALKLEALAVKEDAKMKNEEKDQGQPKKPLDEDK", "length": 71 }, "evidence": [ { "id": "A0A8V0YH48", "url": "https://omabrowser.org/oma/group/A0A8V0YH48/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5SPN9-1", "protein_name": "cAMP-dependent protein kinase inhibitor", "gene_name": "pkib", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTDVEPVVSDFAATGRTGRRNALPDILGSTAGPGAADLPDKLAELTVGDDGEQGGESSSSTDPPKESTEGAKTEGS", "length": 76 }, "evidence": [ { "id": "A0A8V0YH48", "url": "https://omabrowser.org/oma/group/A0A8V0YH48/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q9C010-1", "protein_name": "cAMP-dependent protein kinase inhibitor beta", "gene_name": "PKIB", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRTDSSKMTDVESGVANFASSARAGRRNALPDIQSSAATDGTSDLPLKLEALSVKEDAKEKDEKTTQDQLEKPQNEEK", "length": 78 }, "evidence": [ { "id": "A0A8V0YH48", "url": "https://omabrowser.org/oma/group/A0A8V0YH48/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "cAMP-dependent protein kinase inhibitor activity", "id": "GO:0004862", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004862", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YH48", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH48" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YH48", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH48" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YH48", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH48" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 76, "end_pos": 78, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 76, "end_pos": 78 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": 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"total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YG32-1", "uniprot_ac": "A0A8V0YG32", "uniprot_id": "A0A8V0YG32_CHICK", "mass": { "chemical_mass": 40845.0, "monoisotopic_mass": 40845.0 }, "refseq": {}, "gene_names": [ { "name": "PCGF3", "type": "recommended", "evidence": [ { "id": "A0A8V0YG32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG32" } ] } ], "protein_names": [ { "name": "Polycomb group RING finger protein 3", "type": "recommended", "evidence": [ { "id": "A0A8V0YG32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG32/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YG32", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG32" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PCGF3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG32", "locus": { "chromosome": "Z", "start_pos": 53298298, "end_pos": 53353554, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012551", "url": "https://www.ensembl.org/id/ENSGALG00010012551" } ] } } ], "crossref": [ { "id": "A0A8V0YG32", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YG32", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000015333", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000015333", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd16735", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16735", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd17083", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd17083", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "427287", "url": "https://www.ncbi.nlm.nih.gov/gene/427287", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001841", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001841", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017907", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017907", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032443", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032443", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051507", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051507", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "EHITCEI", "url": "https://omabrowser.org/oma/group/EHITCEI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q2TUT7", "url": "https://www.orthodb.org/?gene=A0A3Q2TUT7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y9S6", "url": "https://www.orthodb.org/?gene=A0A8V0Y9S6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YG32", "url": "https://www.orthodb.org/?gene=A0A8V0YG32", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YMZ1", "url": "https://www.orthodb.org/?gene=A0A8V0YMZ1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45893", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45893", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13923", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13923", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16207", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16207", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A3Q2TUT7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TUT7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2TUT7-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TUT7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y9S6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9S6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y9S6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9S6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YG32", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG32", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YG32-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG32-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YMZ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMZ1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YMZ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMZ1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNPHGRIYTSGHLWPWKSLQYSRYTSQHPCLWIRPCQNTLKPTGDGKRGRYPTPPRLPSPPLALPLPTKDGQGRAGRRRLAERRTPPAAGDRAPPRTRTRRRPPPRQTPKMLTRKIKLWDINAHITCRLCNGYLIDATTVTECLHTFCRSCLVKYLEENNTCPTCRIVIHQSHPLQYIGHDRTMQDIVYKLVPGLQEAEMKKQREFYHKLGMEVPGDIKGETCSAKQHLDSHRNGETKTDENSNKETSEEKQEEDNDYHRSDEQVSICLECNSSKLRGLKRKWIRCSAQATVLHLKKFIAKKLNLSSFNELDILCNEEILGKDHTLKFVVVTRWRFKKAPLLLHYRPKMDLL", "length": 352, "header": "tr|A0A8V0YG32-1|A0A8V0YG32_CHICK Isoform 1 of Polycomb group RING finger protein 3 OS=Gallus gallus OX=9031 GN=PCGF3 PE=4 SV=1 CANONICAL=A0A8V0YG32-1" }, "isoforms": [ { "isoform_ac": "A0A3Q2TUT7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG32/entry#A0A3Q2TUT7-1", "sequence": { "sequence": "MRNSIPNGEERKINVMALKTPKMLTRKIKLWDINAHITCRLCNGYLIDATTVTECLHTFCRSCLVKYLEENNTCPTCRIVIHQSHPLQYIGHDRTMQDIVYKLVPGLQEAEMKKQREFYHKLGMEVPGDIKGETCSAKQHLDSHRNGETKTDENSNKETSEEKQEEDNDYHRSDEQVSICLECNSSKLRGLKRKWIRCSAQATVLHLKKFIAKKLNLSSFNELDILCNEEILGKDHTLKFVVVTRWRFKKAPLLLHYRPKMDLL", "length": 264, "header": "tr|A0A3Q2TUT7-1|A0A3Q2TUT7_CHICK Computationally mapped isoform of Polycomb group RING finger protein 3 OS=Gallus gallus OX=9031 GN=PCGF3 PE=4 SV=1 CANONICAL=A0A8V0YG32-1" }, "locus": { "chromosome": "Z", "start_pos": 53342039, "end_pos": 53303621, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030090.1", "url": "https://www.ensembl.org/id/ENSGALT00010030090.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017481.1", "url": "https://www.ensembl.org/id/ENSGALP00010017481.1" } ] } }, { "isoform_ac": "A0A8V0Y9S6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG32/entry#A0A8V0Y9S6-1", "sequence": { "sequence": "MFQDFKTPKMLTRKIKLWDINAHITCRLCNGYLIDATTVTECLHTFCRSCLVKYLEENNTCPTCRIVIHQSHPLQYIGHDRTMQDIVYKLVPGLQEAEMKKQREFYHKLGMEVPGDIKGETCSAKQHLDSHRNGETKTDENSNKETSEEKQEEDNDYHRSDEQVSICLECNSSKLRGLKRKWIRCSAQATVLHLKKFIAKKLNLSSFNELDILCNEEILGKDHTLKFVVVTRWRFKKAPLLLHYRPKMDLL", "length": 251, "header": "tr|A0A8V0Y9S6-1|A0A8V0Y9S6_CHICK Computationally mapped isoform of Polycomb group RING finger protein 3 OS=Gallus gallus OX=9031 GN=PCGF3 PE=4 SV=1 CANONICAL=A0A8V0YG32-1" }, "locus": { "chromosome": "Z", "start_pos": 53337082, "end_pos": 53303621, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030082.1", "url": "https://www.ensembl.org/id/ENSGALT00010030082.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017477.1", "url": "https://www.ensembl.org/id/ENSGALP00010017477.1" } ] } }, { "isoform_ac": "A0A8V0YG32-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG32/entry#A0A8V0YG32-1", "sequence": { "sequence": "MNPHGRIYTSGHLWPWKSLQYSRYTSQHPCLWIRPCQNTLKPTGDGKRGRYPTPPRLPSPPLALPLPTKDGQGRAGRRRLAERRTPPAAGDRAPPRTRTRRRPPPRQTPKMLTRKIKLWDINAHITCRLCNGYLIDATTVTECLHTFCRSCLVKYLEENNTCPTCRIVIHQSHPLQYIGHDRTMQDIVYKLVPGLQEAEMKKQREFYHKLGMEVPGDIKGETCSAKQHLDSHRNGETKTDENSNKETSEEKQEEDNDYHRSDEQVSICLECNSSKLRGLKRKWIRCSAQATVLHLKKFIAKKLNLSSFNELDILCNEEILGKDHTLKFVVVTRWRFKKAPLLLHYRPKMDLL", "length": 352, "header": "tr|A0A8V0YG32-1|A0A8V0YG32_CHICK Isoform 1 of Polycomb group RING finger protein 3 OS=Gallus gallus OX=9031 GN=PCGF3 PE=4 SV=1 CANONICAL=A0A8V0YG32-1" }, "locus": { "chromosome": "Z", "start_pos": 53353514, "end_pos": 53303621, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030094.1", "url": "https://www.ensembl.org/id/ENSGALT00010030094.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017484.1", "url": "https://www.ensembl.org/id/ENSGALP00010017484.1" } ] } }, { "isoform_ac": "A0A8V0YMZ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG32/entry#A0A8V0YMZ1-1", "sequence": { "sequence": "MALKTPKMLTRKIKLWDINAHITCRLCNGYLIDATTVTECLHTFCRSCLVKYLEENNTCPTCRIVIHQSHPLQYIGHDRTMQDIVYKLVPGLQEAEMKKQREFYHKLGMEVPGDIKGETCSAKQHLDSHRNGETKTDENSNKETSEEKQEEDNDYHRSDEQVSICLECNSSKLRGLKRKWIRCSAQATVLHLKKFIAKKLNLSSFNELDILCNEEILGKDHTLKFVVVTRWRFKKAPLLLHYRPKMDLL", "length": 249, "header": "tr|A0A8V0YMZ1-1|A0A8V0YMZ1_CHICK Computationally mapped isoform of Polycomb group RING finger protein 3 OS=Gallus gallus OX=9031 GN=PCGF3 PE=4 SV=1 CANONICAL=A0A8V0YG32-1" }, "locus": { "chromosome": "Z", "start_pos": 53341994, "end_pos": 53303621, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030103.1", "url": "https://www.ensembl.org/id/ENSGALT00010030103.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017488.1", "url": "https://www.ensembl.org/id/ENSGALP00010017488.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 53, "start_aa": "Thr", "end_pos": 53, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr53", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A4X1T6D0-1", "protein_name": "Polycomb group RING finger protein 3", "gene_name": "PCGF3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MLTRKIKLWDINAHITCRLCSGYLIDATTVTECLHTFCRSCLVKYLEENNTCPTCRIVIHQSHPLQYIGHDRTMQDIVYKLVPGLQEAEMRKQREFYHKLGLEVPGDVKGETCSAKQHLDSHRNGETKAEDSSNKEAAEEKQEEDGDYHRSDEQVSICLECNSSKLRGLKRKWIRCSAQATVLHLKKFIAKKLNLSSFNELDILCNEEILGKDHTLKFVVVTRWRFKKAPLLLHYRPKMDLL", "length": 242 }, "evidence": [ { "id": "A0A8V0YG32", "url": "https://omabrowser.org/oma/group/A0A8V0YG32/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F7EV63-1", "protein_name": "Polycomb group RING finger protein 3", "gene_name": "Pcgf3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLTRKIKLWDINAHITCRLCSGYLIDATTVTECLHTFCRSCLVKYLEENNTCPTCRIVIHQSHPLQYIGHDRTMQDIVYKLVPGLQEGELMLFSSSSELGFGSWTQTLSSQHPYFPHAIVLDSPLDAQKKVRHTQKHGHSLLRRKSQIFICLECNSSKLRGLKRKWIRCSAQATVLHLKKFIAKKLNLSSFNELDILCNEEILGKDHTLKFVVVTRWRFKKAPLLLHYRPKMDLL", "length": 235 }, "evidence": [ { "id": "A0A8V0YG32", "url": "https://omabrowser.org/oma/group/A0A8V0YG32/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3HEE1-1", "protein_name": "Polycomb group RING finger protein 3", "gene_name": "Pcgf3", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MLTRKIKLWDINAHITCRLCSGYLIDATTVTECLHTFCRSCLVKYLEENNTCPTCRIVIHQSHPLQYIGHDRTMQDIVYKLVPGLQEAEMRKQREFYHKLGMEVPGDIKGEACSAKQHLDPRNGETKADDSSNKETAEEKQEEDNDYHRSDEQVSICLECNSSKLRGLKRKWIRCSAQATVLHLKKFIAKKLNLSSFNELDILCNEEILGKDHTLKFVVVTRWRFKKAPLLLHYRPKMDLL", "length": 241 }, "evidence": [ { "id": "A0A8V0YG32", "url": "https://omabrowser.org/oma/group/A0A8V0YG32/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q2KJ29-1", "protein_name": "Polycomb group RING finger protein 3", "gene_name": "PCGF3", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MLTRKIKLWDINAHITCRLCSGYLIDATTVTECLHTFCRSCLVKYLEENNTCPTCRIVIHQSHPLQYIGHDRTMQDIVYKLVPGLQEAEMRKQREFYHKLGLEVPGDIKGETCSAKQHLDPHRNGETKADDSSNKEAAEEKQEEDGDYHRSDEQVSICLECNSSKLRGLKRKWIRCSAQATVLHLKKFIAKKLNLSSFNELDILCNEEILGKDHTLKFVVVTRWRFKKAPLLLHYRPKMDLL", "length": 242 }, "evidence": [ { "id": "A0A8V0YG32", "url": "https://omabrowser.org/oma/group/A0A8V0YG32/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q3KNV8-1", "protein_name": "Polycomb group RING finger protein 3", "gene_name": "PCGF3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLTRKIKLWDINAHITCRLCSGYLIDATTVTECLHTFCRSCLVKYLEENNTCPTCRIVIHQSHPLQYIGHDRTMQDIVYKLVPGLQEAEMRKQREFYHKLGMEVPGDIKGETCSAKQHLDSHRNGETKADDSSNKEAAEEKPEEDNDYHRSDEQVSICLECNSSKLRGLKRKWIRCSAQATVLHLKKFIAKKLNLSSFNELDILCNEEILGKDHTLKFVVVTRWRFKKAPLLLHYRPKMDLL", "length": 242 }, "evidence": [ { "id": "A0A8V0YG32", "url": "https://omabrowser.org/oma/group/A0A8V0YG32/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8BTQ0-1", "protein_name": "Polycomb group RING finger protein 3", "gene_name": "PcgF3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLTRKIKLWDINAHITCRLCSGYLIDATTVTECLHTFCRSCLVKYLEENNTCPTCRIVIHQSHPLQYIGHDRTMQDIVYKLVPGLQEAEMRKQREFYHKLGMEVPGDIKGEACSAKQHLDPRNGETKADDNSNKETAEEKQEEDNDYHRSDEQVSICLECNSSKLRGLKRKWIRCSAQATVLHLKKFIAKKLNLSSFNELDILCNEEILGKDHTLKFVVVTRWRFKKAPLLLHYRPKMDLL", "length": 241 }, "evidence": [ { "id": "A0A8V0YG32", "url": "https://omabrowser.org/oma/group/A0A8V0YG32/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VV77-1", "protein_name": "Polycomb group RING finger protein 3", "gene_name": "l(3)73Ah", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MERRVKLKTINPHITCKICGGYFIDATTVTECLHTFCKSCLVKHLEEKKTCPTCDNIIHQSHPLQYISFDRTMQDIVYKLVPKLQEDESRRERDFYKSRNMPCPKDITQNHEDDNEKVMDAHAESDFHRLDEQVNVCLECISNNFKNLQRRFIRCSSQATITHLKKLVAKKILNGIEKYREIDILCNEELLGKDHTLKFVYVTRWRFRDPPLRLQFRPRVEL", "length": 222 }, "evidence": [ { "id": "A0A8V0YG32", "url": "https://omabrowser.org/oma/group/A0A8V0YG32/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YG32", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG32" } ], "pmid": "" }, { "name": "PRC1 complex", "id": "GO:0035102", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035102", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YG32", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG32" } ], "pmid": "" }, { "name": "PcG protein complex", "id": "GO:0031519", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031519", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YG32", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG32" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YG32", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG32" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YG32", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG32" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YG32", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG32" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 159, "end_pos": 161, "annotation": "n_glycosylation_sequon" }, { "start_pos": 272, "end_pos": 274, "annotation": "n_glycosylation_sequon" }, { "start_pos": 304, "end_pos": 306, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YG32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG32" }, { "id": "PS50089", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50089" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RING-type", "eco_id": "ECO_0000259", "start_pos": 127, "end_pos": 166, "start_aa": "Cys", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 53 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 159, "end_pos": 161 }, { "start_pos": 272, "end_pos": 274 }, { "start_pos": 304, "end_pos": 306 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": 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"url": "https://www.uniprot.org/uniprotkb/A0A8V0YG38" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG38", "locus": {} } ], "crossref": [ { "id": "A0A8V0YG38", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YG38", "database": "AlphaFoldDB", "categories": [] }, { "id": "PTHR34147", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR34147", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR34147:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR34147:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YG38", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG38", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YG38-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG38-1", "database": "UniProtKB", "categories": [ "Protein" ] 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"MGSYGVLWSFMGSYGILWGPYRVKGFYGILWGLMGSYVVLWASMGFYGILWGSYGVKSLYGVLWGLMGSYEVLWDQECLWGPMGFCGILWGPMGSYGVLWSQGSLWGPMGLCGILWGPCRVKGLMGFYGLLWGPYRVRGLYGVLWGPMGFYGILWGSYGVKSLYGVLWGLMGSYEVLWDQECLWGPMGLCGILWGQGSLWGPMGFYGILWGPMGSYGVLWSQGFLWGPMGFYGVLWGLMGSYGLRGLYGILCGPMGSYGVLWGSMGSYGVLWSQGSLWGPMGFYGILWGSYGVKSLYGVLWGLMGSYEVLWDQGSLWGRMGFYGILWGPMGSYGVLWSQGSLWGPMGLCGILRVLWGPMGSYGILWGPYRVKGLYGVLWGPMGFL", "length": 385, "header": "tr|A0A8V0YG38-1|A0A8V0YG38_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0YG38-1" }, "locus": { "chromosome": "W", "start_pos": 366251, "end_pos": 365039, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028930.1", "url": "https://www.ensembl.org/id/ENSGALT00010028930.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016689.1", "url": "https://www.ensembl.org/id/ENSGALP00010016689.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": 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"total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YG44-1", "uniprot_ac": "A0A8V0YG44", "uniprot_id": "A0A8V0YG44_CHICK", "mass": { "chemical_mass": 107736.0, "monoisotopic_mass": 107736.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Reverse transcriptase domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A8V0YG44", "database": "UniProtKB", "url": 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Classification" ] }, { "id": "IPR005135", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005135", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036691", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036691", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043502", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043502", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR33332", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR33332", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00078", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00078", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF03372", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03372", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YG44", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG44", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YG44-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG44-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAARDEPGGAIIGLGVRREAQLKCVYTNARSMGNKQEELEAIVQQASYDLVAITETWWDHSHDWSAAMDGYKLFGKDRQGRRGGGRALYVKECFEVTELMTGENKVESLWVKIRGRADKADILVGVCYRPPNQDEEADELFYEQLAEAAQSPALVLMGDFNLPNICWEYKIAQKKQSRRFLECMEDNFLMQMIREPTRGTAPLDLLFKNRESLVGDVEVGGCLGQSDHDMVEFSIVGGVRRGNSKTATLDFWRVDFELFRRLVGRVPWGSVLESKGVQDGWLLFKKEVLKAQEQAVPLSRKMSRRGRRPVWMNRELFLRKKRIYLLWKKGRTTRKEYKEVVKMCREKIRKAKAQLELNLAAGVKGNKKLLYKYINSKSRTRENLHSLLDEAGNVTTEDKEKADVLNAFFTSVFKSQTSYPQGTLLSVLAALAGVQTKPPTIQEETVRDLLLQLDCHKSMGPDEIHPRVLRELAEEIAEPLYIIYQRSLLTGDVPEDWRLANVTPIYKKGCREDPGNYRPVSLTSVPGKIMEQIVLREITRHVRDNRGIRPSQHGFTKGRSCLTNLISFYDLVTRLVDEGKAVDVVYPDFSKAFDTVSHSILLQKLADRGLDRYTLGWVRNWLEGRAQRVVVNGVKSSWQPVMSGVPQGSVLGPVLFNIFTDDLDEGIECTLSKFADDTKLAGSVDMPEGSEALQRDLDRLDSWAEANGMRFNKTKCRVLHFGRNNLRQRYRLGTEWLEDCVEEMDLGVLIEARLNISQQCAQEAEKANGILACIRNSVASRNNEVIIPLYSALVRPHLEYCVQFWTPHCKKDIEALERVQRRATKLVRGLEHRLYEERLNKLGLFSLEKRRLRGDLIALFNYLKGGCSELGVSLFSRVTSDRTRGNSFKLRQGRFRLDIRKYYFYERVVRHWNGLPREVVESPSLVVFKERLDVVLRDMV", "length": 940, "header": "tr|A0A8V0YG44-1|A0A8V0YG44_CHICK Isoform 1 of Reverse transcriptase domain-containing protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0YG44-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YG44-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG44/entry#A0A8V0YG44-1", "sequence": { "sequence": 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"tr|A0A8V0YG44-1|A0A8V0YG44_CHICK Isoform 1 of Reverse transcriptase domain-containing protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0YG44-1" }, "locus": { "chromosome": "W", "start_pos": 6745987, "end_pos": 6743168, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030799.1", "url": "https://www.ensembl.org/id/ENSGALT00010030799.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017867.1", "url": "https://www.ensembl.org/id/ENSGALP00010017867.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "catalytic activity", "id": "GO:0003824", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003824", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YG44", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG44" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 393, "end_pos": 395, "annotation": "n_glycosylation_sequon" }, { "start_pos": 501, "end_pos": 503, "annotation": "n_glycosylation_sequon" }, { "start_pos": 712, "end_pos": 714, "annotation": "n_glycosylation_sequon" }, { "start_pos": 755, "end_pos": 757, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YG44", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG44" }, { "id": "PS50878", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50878" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Reverse transcriptase", "eco_id": "ECO_0000259", "start_pos": 486, "end_pos": 741, "start_aa": "Arg", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], 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"UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG54/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Plays a role in cell adhesion. May play a role in cell-collagen interactions.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YAT1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAT1#function" }, { "database": "UniProtKB", "id": "ARBA00045945", "url": "https://www.uniprot.org/uniprotkb/ARBA00045945#function" }, { "database": "UniProtKB", "id": "A0A8V0YG54", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG54#function" }, { "database": "UniProtKB", "id": "A0A8V0YP03", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP03#function" }, { "database": "UniProtKB", "id": "A0A8V0YP08", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP08#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YG54", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG54" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TGFBI", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG54", "locus": { "chromosome": "13", "start_pos": 14773382, "end_pos": 14797962, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012839", "url": "https://www.ensembl.org/id/ENSGALG00010012839" } ] } } ], "crossref": [ { "id": "A0A8V0YG54", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YG54", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR000782", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000782", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011489", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011489", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016666", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016666", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036378", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036378", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050904", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050904", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YAT1", "url": "https://www.orthodb.org/?gene=A0A8V0YAT1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YG54", "url": "https://www.orthodb.org/?gene=A0A8V0YG54", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YP03", "url": "https://www.orthodb.org/?gene=A0A8V0YP03", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YP08", "url": "https://www.orthodb.org/?gene=A0A8V0YP08", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10900", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10900", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10900:SF82", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10900:SF82", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02469", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02469", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YAT1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAT1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YAT1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAT1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YG54", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG54", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YG54-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG54-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YP03", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP03", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YP03-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP03-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YP08", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP08", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YP08-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP08-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRGYQLGPTVLFSSFGGFILCLCPSVYAGEMEQCRDLLKQIYLKAFNVGRWLQAYTMSPNVCAVQKLIGTNRKYFTNCKQWYQRKICGKATVISYECCPGYEKVPGEKGCPAALPLANIYETLGVVGSATTQLYSDRSNLRPEIEGPGTFTIFAPSNEAWASLSAETLDSLVSNVNIELLNALRYHMVNKRVLTDDLKHGTTLNSMYQNLPIQIHHYPNGIVTVNCARLLKADHHATNGVVHVIDKVISTTTNSIQHIVETEESLETLRAAVAASDLNSLLESEGQYTLLAPTNEAFEKIPREMLNRILGDPEALRDLLNHHILKSAMCAEAIIAGLTMETLEGTTLDVGCSGEELTLNGRAIIANKDILATNGVVHFVNELLIPDSAKTLFELAQESEVSESMNLFRQAGLSSHLTGSERVTLLAPVNEVFKDKRPTVDSSMKNLLLNHIVKDQLSSKYLYHGQKLQTLGDKELRVFVYRNNLCIENACIAAHDKRGRFGTLFSVDKMLTPPTGSVMDVLKADHRFSTLVAAIQSAGLMENLNRPGTFTVFAPTNEAFRAMPQGELNKLMGNAKELASILKFHMADEILVSGAVSALVRLKSMQGDKLEVSMKNHVIHVNKEPVAESDIMATNGVIHAVSSVLQPQASRPQERGDEPADPALEIFKQASALSKVSQRNPRLAPVYSRLLAKMKENSGGF", "length": 700, "header": "tr|A0A8V0YG54-1|A0A8V0YG54_CHICK Isoform 1 of Transforming growth factor-beta-induced protein ig-h3 OS=Gallus gallus OX=9031 GN=TGFBI PE=1 SV=1 CANONICAL=A0A8V0YG54-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YAT1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG54/entry#A0A8V0YAT1-1", "sequence": { "sequence": "MWSFCTRPNVCAVQKLIGTNRKYFTNCKQWYQRKICGKATVISYECCPGYEKVPGEKGCPAALPLANIYETLGVVGSATTQLYSDRSNLRPEIEGPGTFTIFAPSNEAWASLSAETLDSLVSNVNIELLNALRYHMVNKRVLTDDLKHGTTLNSMYQNLPIQIHHYPNGIVTVNCARLLKADHHATNGVVHVIDKVISTTTNSIQHIVETEESLETLRAAVAASDLNSLLESEGQYTLLAPTNEAFEKIPREMLNRILGDPEALRDLLNHHILKSAMCAEAIIAGLTMETLEGTTLDVGCSGEELTLNGRAIIANKDILATNGVVHFVNELLIPDSAKTLFELAQESEVSESMNLFRQAGLSSHLTGSERVTLLAPVNEVFKDKRPTVDSSMKNLLLNHIVKDQLSSKYLYHGQKLQTLGDKELRVFVYRNNLCIENACIAAHDKRGRFGTLFSVDKMLTPPTGSVMDVLKADHRFSTLVAAIQSAGLMENLNRPGTFTVFAPTNEAFRAMPQGELNKLMGNAKELASILKFHMADEILVSGAVSALVRLKSMQGDKLEVSMKNHVIHVNKEPVAESDIMATNGVIHAVSSVLQPQASRPQERGDEPADPALEIFKQASALSKVSQRNPRLAPVYSRLLAKMKENSGGF", "length": 649, "header": "tr|A0A8V0YAT1-1|A0A8V0YAT1_CHICK Computationally mapped isoform of Transforming growth factor-beta-induced protein ig-h3 OS=Gallus gallus OX=9031 GN=TGFBI PE=1 SV=1 CANONICAL=A0A8V0YG54-1" }, "locus": { "chromosome": "13", "start_pos": 14791117, "end_pos": 14774369, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030794.1", "url": "https://www.ensembl.org/id/ENSGALT00010030794.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017863.1", "url": "https://www.ensembl.org/id/ENSGALP00010017863.1" } ] } }, { "isoform_ac": "A0A8V0YG54-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG54/entry#A0A8V0YG54-1", "sequence": { "sequence": "MRGYQLGPTVLFSSFGGFILCLCPSVYAGEMEQCRDLLKQIYLKAFNVGRWLQAYTMSPNVCAVQKLIGTNRKYFTNCKQWYQRKICGKATVISYECCPGYEKVPGEKGCPAALPLANIYETLGVVGSATTQLYSDRSNLRPEIEGPGTFTIFAPSNEAWASLSAETLDSLVSNVNIELLNALRYHMVNKRVLTDDLKHGTTLNSMYQNLPIQIHHYPNGIVTVNCARLLKADHHATNGVVHVIDKVISTTTNSIQHIVETEESLETLRAAVAASDLNSLLESEGQYTLLAPTNEAFEKIPREMLNRILGDPEALRDLLNHHILKSAMCAEAIIAGLTMETLEGTTLDVGCSGEELTLNGRAIIANKDILATNGVVHFVNELLIPDSAKTLFELAQESEVSESMNLFRQAGLSSHLTGSERVTLLAPVNEVFKDKRPTVDSSMKNLLLNHIVKDQLSSKYLYHGQKLQTLGDKELRVFVYRNNLCIENACIAAHDKRGRFGTLFSVDKMLTPPTGSVMDVLKADHRFSTLVAAIQSAGLMENLNRPGTFTVFAPTNEAFRAMPQGELNKLMGNAKELASILKFHMADEILVSGAVSALVRLKSMQGDKLEVSMKNHVIHVNKEPVAESDIMATNGVIHAVSSVLQPQASRPQERGDEPADPALEIFKQASALSKVSQRNPRLAPVYSRLLAKMKENSGGF", "length": 700, "header": "tr|A0A8V0YG54-1|A0A8V0YG54_CHICK Isoform 1 of Transforming growth factor-beta-induced protein ig-h3 OS=Gallus gallus OX=9031 GN=TGFBI PE=1 SV=1 CANONICAL=A0A8V0YG54-1" }, "locus": { "chromosome": "13", "start_pos": 14797763, "end_pos": 14774369, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030813.1", "url": "https://www.ensembl.org/id/ENSGALT00010030813.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017877.1", "url": "https://www.ensembl.org/id/ENSGALP00010017877.1" } ] } }, { "isoform_ac": "A0A8V0YP03-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG54/entry#A0A8V0YP03-1", "sequence": { "sequence": "MARPSLPLLLLALGLAAAAKSPYQQVLQHSRLRGRQHGPNVCAVQKLIGTNRKYFTNCKQWYQRKICGKATVISYECCPGYEKVPGEKGCPAALPLANIYETLGVVGSATTQLYSDRSNLRPEIEGPGTFTIFAPSNEAWASLSAETLDSLVSNVNIELLNALRYHMVNKRVLTDDLKHGTTLNSMYQNLPIQIHHYPNGIVTVNCARLLKADHHATNGVVHVIDKVISTTTNSIQHIVETEESLETLRAAVAASDLNSLLESEGQYTLLAPTNEAFEKIPREMLNRILGDPEALRDLLNHHILKSAMCAEAIIAGLTMETLEGTTLDVGCSGEELTLNGRAIIANKDILATNGVVHFVNELLIPDSAKTLFELAQESEVSESMNLFRQAGLSSHLTGSERVTLLAPVNEVFKDKRPTVDSSMKNLLLNHIVKDQLSSKYLYHGQKLQTLGDKELRVFVYRNNLCIENACIAAHDKRGRFGTLFSVDKMLTPPTGSVMDVLKADHRFSTLVAAIQSAGLMENLNRPGTFTVFAPTNEAFRAMPQGELNKLMGNAKELASILKFHMADEILVSGAVSALVRLKSMQGDKLEVSMKNHVIHVNKEPVAESDIMATNGVIHAVSSVLQPQASRPQERGDEPADPALEIFKQASALSKVKGKNTPVYSRLLAKMKENSGGF", "length": 677, "header": "tr|A0A8V0YP03-1|A0A8V0YP03_CHICK Computationally mapped isoform of Transforming growth factor-beta-induced protein ig-h3 OS=Gallus gallus OX=9031 GN=TGFBI PE=1 SV=1 CANONICAL=A0A8V0YG54-1" }, "locus": { "chromosome": "13", "start_pos": 14794073, "end_pos": 14774369, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030802.1", "url": "https://www.ensembl.org/id/ENSGALT00010030802.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017869.1", "url": "https://www.ensembl.org/id/ENSGALP00010017869.1" } ] } }, { "isoform_ac": "A0A8V0YP08-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG54/entry#A0A8V0YP08-1", "sequence": { "sequence": "MARPSLPLLLLALGLAAAAKSPYQQVLQHSRLRGRQHGPNVCAVQKLIGTNRKYFTNCKQWYQRKICGKATVISYECCPGYEKVPGEKGCPAALPLANIYETLGVVGSATTQLYSDRSNLRPEIEGPGTFTIFAPSNEAWASLSAETLDSLVSNVNIELLNALRYHMVNKRVLTDDLKHGTTLNSMYQNLPIQIHHYPNGIVTVNCARLLKADHHATNGVVHVIDKVISTTTNSIQHIVETEESLETLRAAVAASDLNSLLESEGQYTLLAPTNEAFEKIPREMLNRILGDPEALRDLLNHHILKSAMCAEAIIAGLTMETLEGTTLDVGCSGEELTLNGRAIIANKDILATNGVVHFVNELLIPDSAKTLFELAQESEVSESMNLFRQAGLSSHLTGSERVTLLAPVNEVFKDKRPTVDSSMKNLLLNHIVKDQLSSKYLYHGQKLQTLGDKELRVFVYRNNLCIENACIAAHDKRGRFGTLFSVDKMLTPPTGSVMDVLKADHRFSTLVAAIQSAGLMENLNRPGTFTVFAPTNEAFRAMPQGELNKLMGNAKELASILKFHMADEILVSGAVSALVRLKSMQGDKLEVSMKNHVIHVNKEPVAESDIMATNGVIHAVSSVLQPQGRLLLGSAWSHTITAELSPKPPLV", "length": 651, "header": "tr|A0A8V0YP08-1|A0A8V0YP08_CHICK Computationally mapped isoform of Transforming growth factor-beta-induced protein ig-h3 OS=Gallus gallus OX=9031 GN=TGFBI PE=1 SV=1 CANONICAL=A0A8V0YG54-1" }, "locus": { "chromosome": "13", "start_pos": 14794073, "end_pos": 14775470, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030808.1", "url": "https://www.ensembl.org/id/ENSGALT00010030808.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017874.1", "url": "https://www.ensembl.org/id/ENSGALP00010017874.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "angiogenesis", "id": "GO:0001525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001525", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YG54", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG54" } ], "pmid": "" }, { "name": "cell adhesion", "id": "GO:0007155", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007155", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YG54", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG54" } ], "pmid": "" }, { "name": "extracellular matrix organization", "id": "GO:0030198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030198", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YG54", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG54" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YG54", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG54" } ], "pmid": "" }, { "name": "extracellular matrix", "id": "GO:0031012", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031012", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YG54", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG54" } ], "pmid": "" }, { "name": "trans-Golgi network", "id": "GO:0005802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005802", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YG54", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG54" } ], "pmid": "" }, { "name": "cell periphery", "id": "GO:0071944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071944", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YG54", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG54" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YG54", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG54" } ], "pmid": "" }, { "name": "collagen binding", "id": "GO:0005518", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005518", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YG54", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG54" } ], "pmid": "" }, { "name": "cell adhesion molecule binding", "id": "GO:0050839", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050839", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YG54", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG54" } ], "pmid": "" }, { "name": "extracellular matrix binding", "id": "GO:0050840", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050840", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YG54", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG54" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YG54", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG54" }, { "id": "PS51041", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51041" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "EMI", "eco_id": "ECO_0000259", "start_pos": 58, "end_pos": 112, "start_aa": "Ser", "end_aa": "Ala", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0YG54", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG54" }, { "id": "PS50213", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50213" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "FAS1", "eco_id": "ECO_0000259", "start_pos": 113, "end_pos": 248, "start_aa": "Ala", "end_aa": "Ile", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": 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This record is derived from a genomic sequence (NC_052538.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. 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"Protein Classification" ] }, { "id": "PTHR24173", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24173", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24173:SF83", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24173:SF83", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24178", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24178", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24198", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24198", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24198:SF192", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24198:SF192", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00023", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00023", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12796", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12796", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13637", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13637", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_040559340", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040559340", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Y7P4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y7P4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y7P4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y7P4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y992", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y992", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y992-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y992-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y9A3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9A3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y9A3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9A3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YG59", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG59", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YG59-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG59-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAVLKLADQPPLVQAIFSGDPEEIRMLIYKTEDVNALDAEKRTPLHVASFLGDADIIELLILSGARVNAKDNMWLTPLHRAVASRSEEAVQVLIKHSADVNARDKNWQTPLHVAAANKALKCAEIIIPMLSSVNVSDRGGRTALHHAALNGHVEMVNLLLAKGANINAFDKKDRRALHWAAYMGHLEVVALLINHGAEVTCKDKKGYTPLHAASSNGQINIVKHLLNLGVEIDEMNIYGNTALHIACYNGQDSVVNELIDYGANVNQPNNNGFTPLHFAAASTHGALCLELLVNNGADVNIQSKDGKSPLHMTAVHGRFTRSQTLIQNGGEIDCVDKDGNTPLHVAARYGHELLINTLITSGADTAKCGIHNMFPLHLAALNAHSDCCRKLLSSGFEIDTPDSFGRTCLHAAAAGGNVECIKLLQSSGADFNKKDKRGRTPLHYAAANCHFHCIETLVTTGANINETDDWGRTPLHYAAASDMDRKKNILGNSHENAEELERTSEMKEKEAALCLEFLLQNDANPSIQDKEGYNTVHYAAAYGHRQCLELLLEKNSNMFEESDSSATKSPLHLAAYNGHHQALEVLLQSLVDLDIKDEKGRTALDLAAFKGHAECVEALISQGASVTVKDNVTKRTPLHASVINGHTPCLRLLLEVADNPDVTDAKGQTPLMLAVAYGHIDAVSLLLEKEASVDAADLLGCTALHRGIMTGHEECVQMLLEKEVSILCKDARGRTPLHFAAARGHATWLSELLQIALSEEDCSLKDNQGYTPLHWACYNGHENCIEVLLEQKFFRKFYGNSFSPLHCAVINDHENCASMLIGAIDASIVNCKDDKGRTPLHAAAFADHVECLQLLLSHSAQVNAVDHAGKTALMMAAQNGHVGAVDFLVNIAKADLTLRDKDSNTSLHLASSKGHEKCALLILDKIQEQSLINAKNNSLQTPLHIAARNGLKMVVEELLAKGACVLAVDENGHTPALACAPNKDVADCLALILATMMPFSPSSSMTAFNFACYKKDNLGRTHLCDGSTMGSINSYNKPLSNNIGTEDGYNENDSDSETF", "length": 1059, "header": "tr|A0A8V0YG59-1|A0A8V0YG59_CHICK Isoform 1 of Ankyrin repeat domain 44 OS=Gallus gallus OX=9031 GN=ANKRD44 PE=4 SV=1 CANONICAL=A0A8V0YG59-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Y7P4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG59/entry#A0A8V0Y7P4-1", "sequence": { "sequence": "MSSNRHHQLRSGFFRCDYDEYCGEKNGNNVIWDNLFTRLLHSSKPGELLWFSPPLVQAIFSGDPEEIRMLIYKTEDVNALDAEKRTPLHVASFLGDADIIELLILSGARVNAKDNMWLTPLHRAVASRSEEAVQVLIKHSADVNARDKNWQTPLHVAAANKALKCAEIIIPMLSSVNVSDRGGRTALHHAALNGHVEMVNLLLAKGANINAFDKKDRRALHWAAYMGHLEVVALLINHGAEVTCKDKKGYTPLHAASSNGQINIVKHLLNLGVEIDEMNIYGNTALHIACYNGQDSVVNELIDYGANVNQPNNNGFTPLHFAAASTHGALCLELLVNNGADVNIQSKDGKSPLHMTAVHGRFTRSQTLIQNGGEIDCVDKDGNTPLHVAARYGHELLINTLITSGADTAKCGIHNMFPLHLAALNAHSDCCRKLLSSGFEIDTPDSFGRTCLHAAAAGGNVECIKLLQSSGADFNKKDKRGRTPLHYAAANCHFHCIETLVTTGANINETDDWGRTPLHYAAASDMDRKKNILGNSHENAEELERTSEMKEKEAALCLEFLLQNDANPSIQDKEGYNTVHYAAAYGHRQCLELLLEKNSNMFEESDSSATKSPLHLAAYNGHHQALEVLLQSLVDLDIKDEKGRTALDLAAFKGHAECVEALISQGASVTVKDNVTKRTPLHASVINGHTPCLRLLLEVADNPDVTDAKGQTPLMLAVAYGHIDAVSLLLEKEASVDAADLLGCTALHRGIMTGHEECVQMLLEKEVSILCKDARGRTPLHFAAARGHATWLSELLQIALSEEDCSLKDNQGYTPLHWACYNGHENCIEVLLEQKFFRKFYGNSFSPLHCAVINDHENCASMLIGAIDASIVNCKDDKGRTPLHAAAFADHVECLQLLLSHSAQVNAVDHAGKTALMMAAQNGHVGAVDFLVNIAKADLTLRDKDSNTSLHLASSKGHEKCALLILDKIQEQSLINAKNNSLQTPLHIAARNGLKMVVEELLAKGACVLAVDENGK", "length": 1016, "header": "tr|A0A8V0Y7P4-1|A0A8V0Y7P4_CHICK Computationally mapped isoform of Ankyrin repeat domain 44 OS=Gallus gallus OX=9031 GN=ANKRD44 PE=4 SV=1 CANONICAL=A0A8V0YG59-1" }, "locus": { "chromosome": "7", "start_pos": 9732013, "end_pos": 9666758, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026353.1", "url": "https://www.ensembl.org/id/ENSGALT00010026353.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010014977.1", "url": "https://www.ensembl.org/id/ENSGALP00010014977.1" } ] } }, { "isoform_ac": "A0A8V0Y992-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG59/entry#A0A8V0Y992-1", "sequence": { "sequence": "MAVLKLADQPPLVQAIFSGDPEEIRMLIYKTEDVNALDAEKRTPLHVASFLGDADIIELLILSGARVNAKDNMWLTPLHRAVASRSEEAVQVLIKHSADVNARDKNWQTPLHVAAANKALKCAEIIIPMLSSVNVSDRGGRTALHHAALNGHVEMVNLLLAKGANINAFDKKDRRALHWAAYMGHLEVVALLINHGAEVTCKDKKGYTPLHAASSNGQINIVKHLLNLGVEIDEMNIYGNTALHIACYNGQDSVVNELIDYGANVNQPNNNGFTPLHFAAASTHGALCLELLVNNGADVNIQSKDGKSPLHMTAVHGRFTRSQTLIQNGGEIDCVDKDGNTPLHVAARYGHELLINTLITSGADTAKCGIHNMFPLHLAALNAHSDCCRKLLSSGQKYSIVSLFSNEHVLSAGFEIDTPDSFGRTCLHAAAAGGNVECIKLLQSSGADFNKKDKRGRTPLHYAAANCHFHCIETLVTTGANINETDDWGRTPLHYAAASDMDRKCLEFLLQNDANPSIQDKEGYNTVHYAAAYGHRQCLELLLEKNSNMFEESDSSATKSPLHLAAYNGHHQALEVLLQSLVDLDIKDEKGRTALDLAAFKGHAECVEALISQGASVTVKDNVTKRTPLHASVINGHTPCLRLLLEVADNPDVTDAKGQTPLMLAVAYGHIDAVSLLLEKEASVDAADLLGCTALHRGIMTGHEECVQMLLEKEVSILCKDARGRTPLHFAAARGHATWLSELLQIALSEEDCSLKDNQGYTPLHWACYNGHENCIEVLLEQKFFRKFYGNSFSPLHCAVINDHENCASMLIGAIDASIVNCKDDKGRTPLHAAAFADHVECLQLLLSHSAQVNAVDHAGKTALMMAAQNGHVGAVDFLVNIAKADLTLRDKDSNTSLHLASSKGHEKCALLILDKIQEQSLINAKNNSLQTPLHIAARNGLKMVVEELLAKGACVLAVDENGHTPALACAPNKDVADCLALILATMMPFSPSSSMTAFNFACYKKDNLGRTHLCDGSTMGSINSYNKPLSNNIGTEDGYNENDSDSETF", "length": 1050, "header": "tr|A0A8V0Y992-1|A0A8V0Y992_CHICK Computationally mapped isoform of Ankyrin repeat domain 44 OS=Gallus gallus OX=9031 GN=ANKRD44 PE=4 SV=1 CANONICAL=A0A8V0YG59-1" }, "locus": { "chromosome": "7", "start_pos": 9770561, "end_pos": 9664366, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026361.1", "url": "https://www.ensembl.org/id/ENSGALT00010026361.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010014985.1", "url": "https://www.ensembl.org/id/ENSGALP00010014985.1" } ] } }, { "isoform_ac": "A0A8V0Y9A3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG59/entry#A0A8V0Y9A3-1", "sequence": { "sequence": "MAVLKLADQPPLVQAIFSGDPEEIRMLIYKTEDVNALDAEKRTPLHVASFLGDADIIELLILSGARVNAKDNMWLTPLHRAVASRSEEAVQVLIKHSADVNARDKNWQTPLHVAAANKALKCAEIIIPMLSSVNVSDRGGRTALHHAALNGHVEMVNLLLAKGANINAFDKKDRRALHWAAYMGHLEVVALLINHGAEVTCKDKKGYTPLHAASSNGQINIVKHLLNLGVEIDEMNIYGNTALHIACYNGQDSVVNELIDYGANVNQPNNNGFTPLHFAAASTHGALCLELLVNNGADVNIQSKDGKSPLHMTAVHGRFTRSQTLIQNGGEIDCVDKDGNTPLHVAARYGHELLINTLITSGADTAKCGIHNMFPLHLAALNAHSDCCRKLLSSGQKYSIVSLFSNEHVLSAGFEIDTPDSFGRTCLHAAAAGGNVECIKLLQSSGADFNKKDKRGRTPLHYAAANCHFHCIETLVTTGANINETDDWGRTPLHYAAASDMDRKKNILGNSHENAEELERTSEMKEKEAALCLEFLLQNDANPSIQDKEGYNTVHYAAAYGHRQCLELLLEKNSNMFEESDSSATKSPLHLAAYNGHHQALEVLLQSLVDLDIKDEKGRTALDLAAFKGHAECVEALISQGASVTVKDNVTKRTPLHASVINGHTPCLRLLLEVADNPDVTDAKGQTPLMLAVAYGHIDAVSLLLEKEASVDAADLLGCTALHRGIMTGHEECVQMLLEKEVSILCKDARGRTPLHFAAARGHATWLSELLQIALSEEDCSLKDNQGYTPLHWACYNGHENCIEVLLEQKFFRKFYGNSFSPLHCAVINDHENCASMLIGAIDASIVNCKDDKGRTPLHAAAFADHVECLQLLLSHSAQVNAVDHAGKTALMMAAQNGHVGAVDFLVNIAKADLTLRDKDSNTSLHLASSKGHEKCALLILDKIQEQSLINAKNNSLQTPLHIAARNGLKMVVEELLAKGACVLAVDENVSRSNGPRTSSATDVQKEE", "length": 1008, "header": "tr|A0A8V0Y9A3-1|A0A8V0Y9A3_CHICK Computationally mapped isoform of Ankyrin repeat domain 44 OS=Gallus gallus OX=9031 GN=ANKRD44 PE=4 SV=1 CANONICAL=A0A8V0YG59-1" }, "locus": { "chromosome": "7", "start_pos": 9770561, "end_pos": 9663099, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026371.1", "url": "https://www.ensembl.org/id/ENSGALT00010026371.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010014995.1", "url": "https://www.ensembl.org/id/ENSGALP00010014995.1" } ] } }, { "isoform_ac": "A0A8V0YG59-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG59/entry#A0A8V0YG59-1", "sequence": { "sequence": "MAVLKLADQPPLVQAIFSGDPEEIRMLIYKTEDVNALDAEKRTPLHVASFLGDADIIELLILSGARVNAKDNMWLTPLHRAVASRSEEAVQVLIKHSADVNARDKNWQTPLHVAAANKALKCAEIIIPMLSSVNVSDRGGRTALHHAALNGHVEMVNLLLAKGANINAFDKKDRRALHWAAYMGHLEVVALLINHGAEVTCKDKKGYTPLHAASSNGQINIVKHLLNLGVEIDEMNIYGNTALHIACYNGQDSVVNELIDYGANVNQPNNNGFTPLHFAAASTHGALCLELLVNNGADVNIQSKDGKSPLHMTAVHGRFTRSQTLIQNGGEIDCVDKDGNTPLHVAARYGHELLINTLITSGADTAKCGIHNMFPLHLAALNAHSDCCRKLLSSGFEIDTPDSFGRTCLHAAAAGGNVECIKLLQSSGADFNKKDKRGRTPLHYAAANCHFHCIETLVTTGANINETDDWGRTPLHYAAASDMDRKKNILGNSHENAEELERTSEMKEKEAALCLEFLLQNDANPSIQDKEGYNTVHYAAAYGHRQCLELLLEKNSNMFEESDSSATKSPLHLAAYNGHHQALEVLLQSLVDLDIKDEKGRTALDLAAFKGHAECVEALISQGASVTVKDNVTKRTPLHASVINGHTPCLRLLLEVADNPDVTDAKGQTPLMLAVAYGHIDAVSLLLEKEASVDAADLLGCTALHRGIMTGHEECVQMLLEKEVSILCKDARGRTPLHFAAARGHATWLSELLQIALSEEDCSLKDNQGYTPLHWACYNGHENCIEVLLEQKFFRKFYGNSFSPLHCAVINDHENCASMLIGAIDASIVNCKDDKGRTPLHAAAFADHVECLQLLLSHSAQVNAVDHAGKTALMMAAQNGHVGAVDFLVNIAKADLTLRDKDSNTSLHLASSKGHEKCALLILDKIQEQSLINAKNNSLQTPLHIAARNGLKMVVEELLAKGACVLAVDENGHTPALACAPNKDVADCLALILATMMPFSPSSSMTAFNFACYKKDNLGRTHLCDGSTMGSINSYNKPLSNNIGTEDGYNENDSDSETF", "length": 1059, "header": "tr|A0A8V0YG59-1|A0A8V0YG59_CHICK Isoform 1 of Ankyrin repeat domain 44 OS=Gallus gallus OX=9031 GN=ANKRD44 PE=4 SV=1 CANONICAL=A0A8V0YG59-1" }, "locus": { "chromosome": "7", "start_pos": 9770561, "end_pos": 9664366, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026365.1", "url": "https://www.ensembl.org/id/ENSGALT00010026365.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010014989.1", "url": "https://www.ensembl.org/id/ENSGALP00010014989.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 1052, "end_pos": 1054, "annotation": "n_glycosylation_sequon" }, { "start_pos": 134, "end_pos": 136, "annotation": "n_glycosylation_sequon" }, { "start_pos": 465, "end_pos": 467, "annotation": "n_glycosylation_sequon" }, { "start_pos": 631, "end_pos": 633, "annotation": "n_glycosylation_sequon" }, { "start_pos": 904, "end_pos": 906, "annotation": "n_glycosylation_sequon" }, { "start_pos": 936, "end_pos": 938, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1052, "end_pos": 1054 }, { "start_pos": 134, "end_pos": 136 }, { "start_pos": 465, "end_pos": 467 }, { "start_pos": 631, "end_pos": 633 }, { "start_pos": 904, "end_pos": 906 }, { "start_pos": 936, "end_pos": 938 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YG62-1", "uniprot_ac": "A0A8V0YG62", "uniprot_id": "A0A8V0YG62_CHICK", "mass": { "chemical_mass": 35277.0, "monoisotopic_mass": 35277.0 }, "refseq": { "ac": "XP_040514270", "name": "peroxisome assembly protein 26 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040514270" }, "gene_names": [ { "name": "PEX26", "type": "recommended", "evidence": [ { "id": "A0A8V0YG62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG62" } ] }, { "name": "PEX26", "type": "synonym", "evidence": [ { "id": "XP_040514270", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040514270" } ] } ], "protein_names": [ { "name": "Peroxisomal biosis factor 26", "type": "synonym", "evidence": [ { "id": "A0A8V0YG62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG62/entry#names_and_taxonomy" } ] }, { "name": "peroxisome assembly protein 26 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_040514270", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040514270" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052573.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040514270", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040514270" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YG62", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG62" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PEX26", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG62", "locus": { "chromosome": "1", "start_pos": 62107351, "end_pos": 62101700, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012588", "url": "https://www.ensembl.org/id/ENSGALG00010012588" } ] } } ], "crossref": [ { "id": "A0A8V0YG62", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YG62", "database": 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Transcript", "id": "ENSGALT00010028996.1", "url": "https://www.ensembl.org/id/ENSGALT00010028996.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016755.1", "url": "https://www.ensembl.org/id/ENSGALP00010016755.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YG99", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG99" } ], "pmid": "" }, { "name": "ubiquitin-protein transferase activity", "id": "GO:0004842", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004842", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YG99", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG99" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 282, "end_pos": 284, "annotation": "n_glycosylation_sequon" }, { "start_pos": 429, "end_pos": 431, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YG99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG99" }, { "id": "PS50106", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50106" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PDZ", "eco_id": "ECO_0000259", "start_pos": 225, "end_pos": 310, "start_aa": "Thr", "end_aa": "Lys", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0YG99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG99" }, { "id": "PS50089", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50089" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RING-type", "eco_id": "ECO_0000259", "start_pos": 44, "end_pos": 82, "start_aa": "Cys", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 282, "end_pos": 284 }, { "start_pos": 429, "end_pos": 431 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], 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"recommended", "evidence": [ { "id": "A0A8V0YGB7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGB7" } ] }, { "name": "FIG4", "type": "synonym", "evidence": [ { "id": "NP_001385009", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001385009" } ] }, { "name": "SAC3", "type": "synonym", "evidence": [ { "id": "NP_001385009", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001385009" } ] } ], "protein_names": [ { "name": "FIG4 homolog, SAC1 lipid phosphatase domain containing", "type": "synonym", "evidence": [ { "id": "NP_001385009", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001385009" } ] }, { "name": "FIG4 phosphoinositide 5-phosphatase", "type": "synonym", "evidence": [ { "id": "A0A8V0YGB7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGB7/entry#names_and_taxonomy" } ] }, { "name": "Sac domain-containing inositol phosphatase 3", "type": "synonym", "evidence": [ { "id": "NP_001385009", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001385009" } ] }, { "name": "polyphosphoinositide phosphatase", "type": "synonym", "evidence": [ { "id": "NP_001385009", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001385009" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## RNAseq introns :: mixed sample support SAMEA103992290, SAMEA103992323 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000065.1. On Dec 7, 2021 this sequence version replaced XP_015139998.2. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001385009", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001385009" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGB7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGB7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "FIG4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGB7", "locus": { "chromosome": "3", "start_pos": 66483508, "end_pos": 66550149, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010014089", "url": "https://www.ensembl.org/id/ENSGALG00010014089" } ] } } ], "crossref": [ { "id": "A0A8V0YGB7", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YGB7", "database": "AlphaFoldDB", "categories": [] }, { "id": "421762", "url": "https://www.ncbi.nlm.nih.gov/gene/421762", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002013", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002013", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043573", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043573", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "KRKCCAH", "url": "https://omabrowser.org/oma/group/KRKCCAH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YGB7", "url": "https://www.orthodb.org/?gene=A0A8V0YGB7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YMD3", "url": "https://www.orthodb.org/?gene=A0A8V0YMD3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YPH0", "url": "https://www.orthodb.org/?gene=A0A8V0YPH0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YUH2", "url": "https://www.orthodb.org/?gene=A0A8V0YUH2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45738", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45738", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45738:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45738:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02383", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02383", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-1660514", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1660514", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-1660516", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1660516", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-1660517", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1660517", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001385009", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001385009", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YGB7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGB7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YGB7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGB7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YMD3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMD3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YMD3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMD3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YPH0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPH0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YPH0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPH0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YUH2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUH2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YUH2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUH2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPAAAAAPLISSVQKLVLYETRARYFLVGSNPAETKYRVLKIDRTEPKDLVIIDDKHVYTQQEVRELLGRLDLGNRTKIGQKGSSGLSRAVSAFGIVGFIRFLEGYYIVLITKRRKMADIGGHAIYKIEDTNMIYIPNDSVRVTHPDEARYLRIFQNVDLSSNFYFSYSYDLSHSLQYNLTVLRMPLEILKTETTQTRQESFDIFEDEGLSTQGGSGVFGICSKPYEKYVWNGKLLEAVKNTVHHDWLLYIIHGFCGQSKLLIYGRPIYVTLIARRSSKFAGTRFLKRGSNSEGDVANEVETEQILYDASVMSFSAGSYSSYVQVRGSVPLYWSQDISTMMPKPPITLDQADPFAHIAALHFDQMLQRFGSPIIILNLVKEREKRKHERILSEELVAAVTYLNQFLPPEHAIIYIPWDMAKYTKSKLCNVLDRLNVIAESVVKKTGFFVNRPDSYCNVLRPDEKWNELGGCVVSTGRLQTGVLRTNCVDCLDRTNTAQFMVGKCALAYQLYSLGLIDKPNLQFDTDAVRLFEELYEDHGDTLSLQYGGSQLVHRVKTYRKIAPWTQHSKDIMQTLSRYYSNAFSDADRQESINLFLGVFKPVEGKPHLWELPTDFYLHHKNTLSLSQTRRSYTYWWTTGVLKHLPLPFDEVTCAENRRKLTVKKFHKYEEEIDIHNEFFRPYELSSFDETFCLAMTNSTRDFMPKNVGIDPSPFTVRKPDETGKSVLGNKSNREETVLQRKTAASAPPPPSEEAVSSSSEDDSGTDKEDEGAVSQRSTPVKVTDAGDNTKITENVVQSTKDVYGVNLSDVPSEDDITIYARFVQLGQSQHKQDKSSQQFCSKHQLDRVINLIPISSFSQDNIYEVQPPRADRKSIEIFHAHIQAGKGNMQPLGKDDFLMYREYIRNRYL", "length": 909, "header": "tr|A0A8V0YGB7-1|A0A8V0YGB7_CHICK Isoform 1 of FIG4 phosphoinositide 5-phosphatase OS=Gallus gallus OX=9031 GN=FIG4 PE=4 SV=1 CANONICAL=A0A8V0YGB7-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YGB7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGB7/entry#A0A8V0YGB7-1", "sequence": { "sequence": "MPAAAAAPLISSVQKLVLYETRARYFLVGSNPAETKYRVLKIDRTEPKDLVIIDDKHVYTQQEVRELLGRLDLGNRTKIGQKGSSGLSRAVSAFGIVGFIRFLEGYYIVLITKRRKMADIGGHAIYKIEDTNMIYIPNDSVRVTHPDEARYLRIFQNVDLSSNFYFSYSYDLSHSLQYNLTVLRMPLEILKTETTQTRQESFDIFEDEGLSTQGGSGVFGICSKPYEKYVWNGKLLEAVKNTVHHDWLLYIIHGFCGQSKLLIYGRPIYVTLIARRSSKFAGTRFLKRGSNSEGDVANEVETEQILYDASVMSFSAGSYSSYVQVRGSVPLYWSQDISTMMPKPPITLDQADPFAHIAALHFDQMLQRFGSPIIILNLVKEREKRKHERILSEELVAAVTYLNQFLPPEHAIIYIPWDMAKYTKSKLCNVLDRLNVIAESVVKKTGFFVNRPDSYCNVLRPDEKWNELGGCVVSTGRLQTGVLRTNCVDCLDRTNTAQFMVGKCALAYQLYSLGLIDKPNLQFDTDAVRLFEELYEDHGDTLSLQYGGSQLVHRVKTYRKIAPWTQHSKDIMQTLSRYYSNAFSDADRQESINLFLGVFKPVEGKPHLWELPTDFYLHHKNTLSLSQTRRSYTYWWTTGVLKHLPLPFDEVTCAENRRKLTVKKFHKYEEEIDIHNEFFRPYELSSFDETFCLAMTNSTRDFMPKNVGIDPSPFTVRKPDETGKSVLGNKSNREETVLQRKTAASAPPPPSEEAVSSSSEDDSGTDKEDEGAVSQRSTPVKVTDAGDNTKITENVVQSTKDVYGVNLSDVPSEDDITIYARFVQLGQSQHKQDKSSQQFCSKHQLDRVINLIPISSFSQDNIYEVQPPRADRKSIEIFHAHIQAGKGNMQPLGKDDFLMYREYIRNRYL", "length": 909, "header": "tr|A0A8V0YGB7-1|A0A8V0YGB7_CHICK Isoform 1 of FIG4 phosphoinositide 5-phosphatase OS=Gallus gallus OX=9031 GN=FIG4 PE=4 SV=1 CANONICAL=A0A8V0YGB7-1" }, "locus": { "chromosome": "3", "start_pos": 66549975, "end_pos": 66484052, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033839.1", "url": "https://www.ensembl.org/id/ENSGALT00010033839.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019904.1", "url": "https://www.ensembl.org/id/ENSGALP00010019904.1" } ] } }, { "isoform_ac": "A0A8V0YMD3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGB7/entry#A0A8V0YMD3-1", "sequence": { "sequence": "MAWSKRESGLVAWCLFQRYFLVGSNPAETKYRVLKIDRTEPKDLVIIDDKHVYTQQEVRELLGRLDLGNRTKIGQKGSSGLSRAVSAFGIVGFIRFLEGYYIVLITKRRKMADIGGHAIYKIEDTNMIYIPNDSVRVTHPDEARYLRIFQNVDLSSNFYFSYSYDLSHSLQYNLTVLRMPLEILKTETTQTRQESFDIFEDEGLSTQGGSGVFGICSKPYEKYVWNGKLLEAVKNTVHHDWLLYIIHGFCGQSKLLIYGRPIYVTLIARRSSKFAGTRFLKRGSNSEGDVANEVETEQILYDASVMSFSAGSYSSYVQVRGSVPLYWSQDISTMMPKPPITLDQADPFAHIAALHFDQMLQRFGSPIIILNLVKEREKRKHERILSEELVAAVTYLNQFLPPEHAIIYIPWDMAKYTKSKLCNVLDRLNVIAESVVKKTGFFVNRPDSYCNVLRPDEKWNELGGCVVSTGRLQTGVLRTNCVDCLDRTNTAQFMVGKCALAYQLYSLGLIDKPNLQFDTDAVRLFEELYEDHGDTLSLQYGGSQLVHRVKTYRKIAPWTQHSKDIMQTLSRYYSNAFSDADRQESINLFLGVFKPVEGKPHLWELPTDFYLHHKNTLSLSQTRRSYTYWWTTGVLKHLPLPFDEVTCAENRRKLTVKKFHKYEEEIDIHNEFFRPYELSSFDETFCLAMTNSTRDFMPKNVGIDPSPFTVRKPDETGKSVLGNKSNREETVLQRKTAASAPPPPSEEAVSSSSEDDSGTDKEDEGAVSQRSTPVKVTDAGDNTKITENVVQSTKDVYGVNLSDVPSEDDITIYARFVQLGQSQHKQDKSSQQFCSKHQLDRVINLIPISSFSQDNIYEVQPPRADRKSIEIFHAHIQAGKGNMQPLGKDDFLMYREYIRNRYL", "length": 903, "header": "tr|A0A8V0YMD3-1|A0A8V0YMD3_CHICK Computationally mapped isoform of FIG4 phosphoinositide 5-phosphatase OS=Gallus gallus OX=9031 GN=FIG4 PE=4 SV=1 CANONICAL=A0A8V0YGB7-1" }, "locus": { "chromosome": "3", "start_pos": 66541947, "end_pos": 66484052, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033833.1", "url": "https://www.ensembl.org/id/ENSGALT00010033833.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019903.1", "url": "https://www.ensembl.org/id/ENSGALP00010019903.1" } ] } }, { "isoform_ac": "A0A8V0YPH0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGB7/entry#A0A8V0YPH0-1", "sequence": { "sequence": "MKNRNYSLAGRQRYFLVGSNPAETKYRVLKIDRTEPKDLVIIDDKHVYTQQEVRELLGRLDLGNRTKIGQKGSSGLSRAVSAFGIVGFIRFLEGYYIVLITKRRKMADIGGHAIYKIEDTNMIYIPNDSVRVTHPDEARYLRIFQNVDLSSNFYFSYSYDLSHSLQYNLTVLRMPLEILKTETTQTRQESFDIFEDEGLSTQGGSGVFGICSKPYEKYVWNGKLLEAVKNTVHHDWLLYIIHGFCGQSKLLIYGRPIYVTLIARRSSKFAGTRFLKRGSNSEGDVANEVETEQILYDASVMSFSAGSYSSYVQVRGSVPLYWSQDISTMMPKPPITLDQADPFAHIAALHFDQMLQRFGSPIIILNLVKEREKRKHERILSEELVAAVTYLNQFLPPEHAIIYIPWDMAKYTKSKLCNVLDRLNVIAESVVKKTGFFVNRPDSYCNVLRPDEKWNELGGCVVSTGRLQTGVLRTNCVDCLDRTNTAQFMVGKCALAYQLYSLGLIDKPNLQFDTDAVRLFEELYEDHGDTLSLQYGGSQLVHRVKTYRKIAPWTQHSKDIMQTLSRYYSNAFSDADRQESINLFLGVFKPVEGKPHLWELPTDFYLHHKNTLSLSQTRRSYTYWWTTGVLKHLPLPFDEVTCAENRRKLTVKKFHKYEEEIDIHNEFFRPYELSSFDETFCLAMTNSTRDFMPKNVGIDPSPFTVRKPDETGKSVLGNKSNREETVLQRKTAASAPPPPSEEAVSSSSEDDSGTDKEDEGAVSQRSTPVKVTDAGDNTKITENVVQSTKDVYGVNLSDVPSEDDITIYARFVQLGQSQHKQDKSSQQFCSKHQLDRVINLIPISSFSQDNIYEVQPPRADRKSIEIFHAHIQAGKGNMQPLGKDDFLMYREYIRNRYL", "length": 898, "header": "tr|A0A8V0YPH0-1|A0A8V0YPH0_CHICK Computationally mapped isoform of FIG4 phosphoinositide 5-phosphatase OS=Gallus gallus OX=9031 GN=FIG4 PE=4 SV=1 CANONICAL=A0A8V0YGB7-1" }, "locus": { "chromosome": "3", "start_pos": 66549651, "end_pos": 66484052, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033845.1", "url": "https://www.ensembl.org/id/ENSGALT00010033845.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019907.1", "url": "https://www.ensembl.org/id/ENSGALP00010019907.1" } ] } }, { "isoform_ac": "A0A8V0YUH2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGB7/entry#A0A8V0YUH2-1", "sequence": { "sequence": "MPAAAAAPLISSVQKLVLYETRARYFLVGSNPAETKYRVLKIDRTEPKDLVIIDDKHVYTQQEVRELLGRLDLGNRTKIGQKGSSGLSRAVSAFGIVGFIRFLEGYYIVLITKRRKMADIGGHAIYKIEDTNMIYIPNDSVRVTHPDEARYLRIFQNVDLSSNFYFSYSYDLSHSLQYNLTVLRMPLEILKTETTQTRQESFDIFEDEGLSTQGGSGVFGICSKPYEKYVWNGKLLEAVKNTVHHDWLLYIIHGFCGQSKLLIYGRPIYVTLIARRSSKFAGTRFLKRGSNSEGDVANEVETEQILYDASVMSFSAGSYSSYVQVRGSVPLYWSQDISTMMPKPPITLDQADPFAHIAALHFDQMLQRFGSPIIILNLVKEREKRKHERILSEELVAAVTYLNQFLPPEHAIIYIPWDMAKYTKSKLCNVLDRLNVIAESVVKKTGFFVNRPDSYCNVLRPDEKWNELGGCVVSTGRLQTGVLRTNCVDCLDRTNTAQFMVGKCALAYQLYSLGLIDKPNLQFDTDAVRLFEELYEDHGDTLSLQYGGSQLVHRVKTYRKIAPWTQHSKDIMQTLSRYYSNAFSDADRQESINLFLGVFKPVEGKPHLWELPTDFYLHHKNTLSLSQTRRSYTYWWTTGVLKHLPLPFDEVTCAENRRKLTVKKFHKYEEEIDIHNEFFRPYELSSFDETFCLAMTNSTRDFMPKNVGIDPSPFTVRKPDETGKSVLGNKSNREETVLQRKTAASAPPPPSEEAVSSSSEDDSGTDKEDEGAVSQRSTPVKVTDAGDNTKITENVVQSTKDVYGVNLSDVPSEDDITIYARFVQLGQSQHKQDKSSQQFCSKHQLDRVINL", "length": 851, "header": "tr|A0A8V0YUH2-1|A0A8V0YUH2_CHICK Computationally mapped isoform of FIG4 phosphoinositide 5-phosphatase OS=Gallus gallus OX=9031 GN=FIG4 PE=4 SV=1 CANONICAL=A0A8V0YGB7-1" }, "locus": { "chromosome": "3", "start_pos": 66549975, "end_pos": 66494565, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033827.1", "url": "https://www.ensembl.org/id/ENSGALT00010033827.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019900.1", "url": "https://www.ensembl.org/id/ENSGALP00010019900.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-1660514", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1660514", "resource": "Reactome", "description": "Synthesis of PIPs at the Golgi membrane" }, { "id": "R-GGA-1660516", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1660516", "resource": "Reactome", "description": "Synthesis of PIPs at the early endosome membrane" }, { "id": "R-GGA-1660517", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1660517", "resource": "Reactome", "description": "Synthesis of PIPs at the late endosome membrane" } ], "orthologs": [ { "uniprot_canonical_ac": "G3GXM2-1", "protein_name": "Polyphosphoinositide phosphatase isoform X1", "gene_name": "Fig4", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MPTAAAPIISSVQKLVLYETRARYFLVGSNHAETKYRVLKIDRTEPKDLVIIDDRHVYTQQEVRELLGRLDLGNRTKTAQKGASGLFRAVSAFGVVGFVRFLEGYYIVLITKRRKMADIGGHAIYKIEDTNMIYIPNDSVRITHPDEARYLRIFQNVDLSSNFYFSYSYDLSHSLQYNLTVLRMPLEMLKSETSKTRQESFDIFEDEGLITQGGSGVFGISSEPYMKYVWNGELLDIIKTTVHRDWLLYIIHGFCGQSKLLIYGRPVYVTLIARRSSKFAGTRFLKRGANCEGDVANEVETEQILCDASVMSFTAGSYSSYVQVRGSVPLYWSQDISTMMPKPPITLDQADPFAHVAALHFDQMLQRFGSPIIILNLVKEREKRKHERILSEELVAAVTYLNQFLPPEHTIVYIPWDMAKYTKSKLCNVLDRLNVIAESVVKKTGFFVNRPDSYCSTLRPDEKWNELGGCVNPTGRLQTGILRTNCVDCLDRTNTAQFMVGKCALAYQLYSLGLIDKPNLQFDTDAVRLFEELYEDHGDTLSLQYGGSQLVHRVKTYRKIAPWTQHSKDIMQTLSRYYSNAFSDADRQDSINLFLGVFHPTEGKPHLWELPTDFYLHHKNTMSLLPTRRSYTHWWTPEVIQHLPLPYDEVICAANLKKLMVKKFHRCEEEIDIHNEFFRPHELSSFDDTFCLAMTSSARDFMPKTVGIDPSPFTVRKPDETGKSVLGNKSNREEAVLQRKTAASAPPPPSEEAVSSSSEDDSGTDREDEGSVSQRSTPVKMTDPGDSTKVTENVVQPMKEVYGVNLSDTLSEEDFSIYARFVQLGQSQHKQDRNSQQPCSRCSDRVIKLTPISAFSQDNIYEVQPPRVDRKSTEIFQAHIQASRGIMQPLGKEDTAMYREYIRNRYL", "length": 907 }, "evidence": [ { "id": "A0A8V0YGB7", "url": "https://omabrowser.org/oma/group/A0A8V0YGB7/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P42837-1", "protein_name": "Polyphosphoinositide phosphatase", "gene_name": "FIG4", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MNNDAMEHTLGGGILTTSGSKQRKTSKFVMGKYTLYETKDRMYIVGSNKRETMFRILEIDLTVPRGELTVLEDNVFFTRNEIMNVLASLEEATEDGLHKKITGYGLLGFIKFTCWYYLIMVTKYSQVAVIGGHGIYHIDGIDIIPITNNYKKPEKSSDEARLLNIFKDLDLTKTFYFSYTYDITNTLQTNILREKLKAVDRCDITIPCGITDYNEMFVWNNNLLSPIFACIDTVFDWFQCIIHGFIDQVNVSVLGKSIYITLIARRSHHFAGARFLKRGVNNKGHVANEVETEQIVTDMILTPFHQPGNGFFDSDRYTSFVQHRGSIPLYWTQDASNLTTKPPIRINVVDPFFSPAALHFDNLFQRYGGGTIQILNLIKTKEKTPRETKLLWEFEQCIDYLNEFLPTLKKLDYTSWDMSRASKQDGQGVIEFLEKYAVNTVTTTGIFHNGPDFASTKIQEGICRSNCIDCLDRTNAAQFVIGKRALGCQLKSLGIIDNSYLEYDSDIVNILTELFHDLGDTIALQYGGSHLVNTMETYRKINQWSSHSRDMIESIKRFYSNSFVDAQRQDAINLFLGHYSWREGFPSLWEMNTDFYLHNAYSLNMPKRSYIHWWNDYNIKSVKELINEELIATGNDVTREKIIKNVRGYPGAFDNYWNEYYLPRSVTWIRDLFAYNMNSTRRYHNALSKQDKAMSPFTSRKQSWLNNKLKMITSSKSLEKAEGRVVETTDLDRDTSPKQELELYEHYLHIISDRSQKLEEKMNSFSYSKYPIFISHESSEIPPMRKVIGEPLVDIAEDFTDVYDDDDDGDDENDEMTTEALLIAPDHVSVDEKFYEKVLNVDDYKPALDDYSAVIHIKPDNLQLYRDLCFSKDIQLDFQ", "length": 879 }, "evidence": [ { "id": "A0A8V0YGB7", "url": "https://omabrowser.org/oma/group/A0A8V0YGB7/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q7XZU3-1", "protein_name": "Phosphatidylinositol-3-phosphatase SAC1", "gene_name": "SAC1", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MAKSENSTTSTFSSFANKIQPSNDAESDPDSYALEKFKLYETRARFYLVGSDRNKRFFRVLKIDRSEPSELNISEDPVVYSPQEIKSLLQRIAEGNRATGGLAFVAKVYGIAGCAKFMESYYLVLVTKRRQIGCICGHAIYAIDESQMISVPHATIQSDVANSKTELRYKKLLSSVDLTKDFFYSYTYPIMQSLQKNVLSSGEEGMPYDNIFVWNSYLTQPIRSRCNNTIWTLALVHGHFKQIRLSIYGRDFSVTLVSRRSRHFAGTRYLKRGVNDRGRVANDVETEQLVLDDEAGSCKGKMSSVVQMRGSIPLFWSQEASRFSPKPDIFLQRYDPTYESTKMHFEDLVNRYGNPIIVLNLIKTVEKRPREMVLRREFANAVGYLNSIFREENHLKFIHWDFHKFAKSKSANVLAVLGAVASEALDLTGLYFSGKPKIVKKKASQLSHANTAREPSLRDLRAYSAELSRGESANDILSALANREKEMKLTQQKKDEGTNSSAPRYQSGVLRTNCIDCLDRTNVAQYAYGLAALGRQLHAMGLSDTPKIDPDSSIAAALMDMYQSMGDALAQQYGGSAAHNTVFPERQGKWKATTQSREFLKSIKRYYSNTYTDGEKQDAINLFLGYFQPQEGKPALWELDSDYYLHVSGIGDDIFPDIGVQSIAKPMSGIGVNLAPVPAFRDDFSRKKLTSFDKLIEQTCSSIKNVRLCSETDQRPGGNTGSTGVAPDAAEIQLKSPNWLFGSRKPEESSSATKSGADDSEKGVTSTERVNDFCNLDWLSKSDRHQGDIFQRYLSITSTNEANGWYGGTLLGDQDENSEIYRHYAQFCQCPAMEPFENDHEFEQNFAEVLRMNTIDVMDIEEEETEMESDFNEYTQIGSDLGIIPMQCKHFASDPCWLARWLVGDDKVPKVI", "length": 912 }, "evidence": [ { "id": "A0A8V0YGB7", "url": "https://omabrowser.org/oma/group/A0A8V0YGB7/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q91WF7-1", "protein_name": "Polyphosphoinositide phosphatase", "gene_name": "Fig4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPTAAAPIISSVQKLVLYETRARYFLVGSNHAETKYRVLKIDRTEPKDLVVIDDRHVYTQQEVRELLGRLDLGNRTKMSQKGSSGLFRAVSAFGVVGFVRFLEGYYIVLITKRRKMADIGGHAIYKIEDTSMIYIPNDSVRISHPDEARYLRIFQNVDLSSNFYFSYSYDLSHSLQYNLTVLRMPLEMLKSETSKACQESFDIFEDEGLITQGGSGVFGISSEPYMKYVWNGELLDIIKNTVHRDWLLYIIHGFCGQSKLLIYGRPVYVTLIARRSSRFAGTRFLKRGANCEGDVANEVETEQILCDASVMSFTAGSYSSYVQVRGSVPLFWSQDISTMMPKPPITLDQADPFAHVAALHFDQMLQRFGSPIIILNLVKEREKRKHERILSEELVAAVTYLNQFLPPEHTIVYIPWDMAKYTKSKLCNVLDRLNVIAESVVKKTGFFVNRPDSYCSILRPDEKWNELGGHVIPTGRLQTGILRTNCVDCLDRTNTAQFMVGKCALAYQLYSLGLIDKPNLQFDTDAVRLFEELYEDHGDTLSLQYGGSQLVHRVKTYRKIAPWTQHSKDIMQTLSRYYSNAFSDADRQDSINLFLGVFHPTEGKPHLWELPTDFYLHHKNTMSLLPPRRSYTYWWTPEVVKHLPLPYDEVICAANLKKLMVKKFHRWEEEIDIHNEFFRPYELSSFDDTFCLAMTSSARDFMPKTVGIDPSPFTVRKPDETGKSVLGNKNTREEAVLQRKTAASAPPPPSEEAVSSSSEDDSGTDREDEGSISQRSTPVKMTDTGDSAKATENVVQPMKEVYGVSLSSSLSEEDHSIYARFVQLGQSQHKQDRGNQQLCSRCSDGVIKLTPISAFSQDNIYEVQPPRVDRKSTEIFQAHIQASQGIMQPLGKEDTAMYREYIRNRYL", "length": 907 }, "evidence": [ { "id": "A0A8V0YGB7", "url": 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"glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "endosome membrane", "id": "GO:0010008", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010008", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGB7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGB7" } ], "pmid": "" }, { "name": "endomembrane system", "id": "GO:0012505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0012505", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGB7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGB7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "phosphatidylinositol dephosphorylation", "id": "GO:0046856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046856", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGB7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGB7" } ], "pmid": "" }, { "name": "1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate metabolic process", "id": "GO:1903100", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903100", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGB7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGB7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity", "id": "GO:0043813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043813", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGB7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGB7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 138, "end_pos": 140, "annotation": "n_glycosylation_sequon" }, { "start_pos": 179, "end_pos": 181, "annotation": "n_glycosylation_sequon" }, { "start_pos": 697, "end_pos": 699, "annotation": "n_glycosylation_sequon" }, { "start_pos": 729, "end_pos": 731, "annotation": "n_glycosylation_sequon" }, { "start_pos": 75, "end_pos": 77, "annotation": "n_glycosylation_sequon" }, { "start_pos": 806, "end_pos": 808, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YGB7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGB7" }, { "id": "PS50275", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50275" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SAC", "eco_id": "ECO_0000259", "start_pos": 155, "end_pos": 548, "start_aa": "Phe", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YGC9-1", "uniprot_ac": "A0A8V0YGC9", "uniprot_id": "A0A8V0YGC9_CHICK", "mass": { "chemical_mass": 38110.0, "monoisotopic_mass": 38110.0 }, "refseq": {}, "gene_names": [ { "name": "GSG1", "type": "recommended", "evidence": [ { "id": "A0A8V0YGC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGC9" } ] } ], "protein_names": [ { "name": "Germ cell associated 1", "type": "synonym", "evidence": [ { "id": "A0A8V0YGC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGC9/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGC9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGC9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "GSG1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGC9", "locus": { "chromosome": "1", "start_pos": 48328214, "end_pos": 48340905, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010011038", "url": "https://www.ensembl.org/id/ENSGALG00010011038" } ] } } ], "crossref": [ { "id": "A0A8V0YGC9", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YGC9", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR012478", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012478", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050579", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050579", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y7W8", "url": "https://www.orthodb.org/?gene=A0A8V0Y7W8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YGC9", "url": "https://www.orthodb.org/?gene=A0A8V0YGC9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10671", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10671", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10671:SF43", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10671:SF43", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07803", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07803", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { 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OS=Gallus gallus OX=9031 GN=GSG1 PE=3 SV=1 CANONICAL=A0A8V0YGC9-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Y7W8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGC9/entry#A0A8V0Y7W8-1", "sequence": { "sequence": "MELLKMLPWRRAFLAVILNLLALSLSTTALLSSYWCTGTQKVPKPLCGKSKDSKCIGVPMTPDAAASNASAQEEVHYSWETGDDRFSFRYFHTGMWLSCEESMEGPGILWLSLGSEMLYISLLLISFILLMVEMLHTGNPVCGLKLNAFAAVSSVLSGLLGMVAHMMYSQVFQATVNLGPEDWRPHTWDYGWAFYMAWTSFTCCMASAVTTLNTYTKTVLEFKRNHIKGYDMSFKDQPQHHQYFIQQHISSYYESRDKPLHSVSEGVDFYSELQKKVLQREPELDLDEVLGQTIREDQC", "length": 299, "header": "tr|A0A8V0Y7W8-1|A0A8V0Y7W8_CHICK Computationally mapped isoform of Germ cell associated 1 OS=Gallus gallus OX=9031 GN=GSG1 PE=3 SV=1 CANONICAL=A0A8V0YGC9-1" }, "locus": { "chromosome": "1", "start_pos": 48335773, "end_pos": 48329109, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026444.1", "url": "https://www.ensembl.org/id/ENSGALT00010026444.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015053.1", "url": "https://www.ensembl.org/id/ENSGALP00010015053.1" } ] } }, { "isoform_ac": "A0A8V0YGC9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGC9/entry#A0A8V0YGC9-1", "sequence": { "sequence": "MKSRVPLGICQLSVAIVGPYLMELLKMLPWRRAFLAVILNLLALSLSTTALLSSYWCTGTQKVPKPLCGKSKDSKCIGVPMTPDAAASNASAQEEVHYSWETGDDRFSFRYFHTGMWLSCEESMEGPEEKCRSFIELSPPAERGILWLSLGSEMLYISLLLISFILLMVEMLHTGNPVCGLKLNAFAAVSSVLSGLLGMVAHMMYSQVFQATVNLGPEDWRPHTWDYGWAFYMAWTSFTCCMASAVTTLNTYTKTVLEFKRNHIKGYDMSFKDQPQHHQYFIQQHISSYYESRDKPLHSVSEGVDFYSELQKKVLQREPELDLDEVLGQTIREDQC", "length": 336, "header": "tr|A0A8V0YGC9-1|A0A8V0YGC9_CHICK Isoform 1 of Germ cell associated 1 OS=Gallus gallus OX=9031 GN=GSG1 PE=3 SV=1 CANONICAL=A0A8V0YGC9-1" }, "locus": { "chromosome": "1", "start_pos": 48340562, "end_pos": 48329109, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026448.1", "url": "https://www.ensembl.org/id/ENSGALT00010026448.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015055.1", "url": "https://www.ensembl.org/id/ENSGALP00010015055.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGC9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGC9" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGC9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGC9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 89, "end_pos": 91, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], 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"recommended", "evidence": [ { "id": "A0A8V0YGE5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGE5/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGE5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGE5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGE5", "locus": {} } ], "crossref": [ { "id": "A0A8V0YGE5", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YGE5", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR006569", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006569", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008942", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008942", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PF04818", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04818", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YGE5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGE5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YGE5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGE5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNEQRSFSEALKRKLSELSNSRQSAQTQSQWLIHHRKHPVLIVSLQEQELRRMLLRPVLVFGPSLIPAVGNHALYVSEPFSCCHSCFFLQERESFCYKQILFFFLLKENIMGYLWESKQTFSSLQKGSEID", "length": 131, "header": "tr|A0A8V0YGE5-1|A0A8V0YGE5_CHICK Isoform 1 of CID domain-containing protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0YGE5-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YGE5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGE5/entry#A0A8V0YGE5-1", "sequence": { "sequence": "MNEQRSFSEALKRKLSELSNSRQSAQTQSQWLIHHRKHPVLIVSLQEQELRRMLLRPVLVFGPSLIPAVGNHALYVSEPFSCCHSCFFLQERESFCYKQILFFFLLKENIMGYLWESKQTFSSLQKGSEID", "length": 131, "header": "tr|A0A8V0YGE5-1|A0A8V0YGE5_CHICK Isoform 1 of CID domain-containing protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0YGE5-1" }, "locus": { "chromosome": "2", "start_pos": 69262054, "end_pos": 69261176, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026473.1", "url": "https://www.ensembl.org/id/ENSGALT00010026473.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015071.1", "url": "https://www.ensembl.org/id/ENSGALP00010015071.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YGE5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGE5" }, { "id": "PF04818", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04818" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CID", "eco_id": "ECO_0000259", "start_pos": 9, "end_pos": 52, "start_aa": "Glu", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YGF8-1", "uniprot_ac": "A0A8V0YGF8", "uniprot_id": "A0A8V0YGF8_CHICK", "mass": { "chemical_mass": 127718.0, "monoisotopic_mass": 127718.0 }, "refseq": { "ac": "NP_001007083", "name": "transient receptor potential cation channel subfamily M member 8", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001007083" }, "gene_names": [ { "name": "TRPM8", "type": "recommended", "evidence": [ { "id": "A0A8V0YGF8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGF8" } ] }, { "name": "TRPM8", "type": "synonym", "evidence": [ { "id": "NP_001007083", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001007083" } ] } ], "protein_names": [ { "name": "Transient receptor potential cation channel subfamily M member 8", "type": "synonym", "evidence": [ { "id": "A0A8V0YGF8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGF8/entry#names_and_taxonomy" } ] }, { "name": "menthol receptor", "type": "synonym", "evidence": [ { "id": "NP_001007083", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001007083" } ] }, { "name": "transient receptor potential cation channel subfamily M member 8", "type": "synonym", "evidence": [ { "id": "NP_001007083", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001007083" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992428 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000235.1. On Dec 15, 2021 this sequence version replaced NP_001007083.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001007083", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001007083" } ] }, { "annotation": "Results indicate that cTRPM8 acts as a cold-sensor similar to mammals. It is noteworthy that TRPM8-independent cold-sensitive neurons are abundant in chicken sensory neurons. Our results suggest that most of the cold-induced [Ca(2+)]i increases are mediated via Ca(2+) release from intracellular stores and that these mechanisms may be specific to avian species.", "evidence": [ { "database": "RefSeq", "id": "NP_001007083", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001007083" }, { "database": "PubMed", "id": "27590914", "url": "https://glygen.org/publication/PubMed/27590914" } ] }, { "annotation": "The effects of neuronal cell differentiation on TRPM7, TRPM8 and TRPV1 channels in the model of Parkinson's disease.", "evidence": [ { "database": "RefSeq", "id": "NP_001007083", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001007083" }, { "database": "PubMed", "id": "34256685", "url": "https://glygen.org/publication/PubMed/34256685" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGF8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGF8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TRPM8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGF8", "locus": { "chromosome": "7", "start_pos": 5669112, "end_pos": 5595417, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012680", "url": "https://www.ensembl.org/id/ENSGALG00010012680" } ] } } ], "crossref": [ { "id": "A0A8V0YGF8", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YGF8", "database": "AlphaFoldDB", "categories": [] }, { "id": "424025", "url": "https://www.ncbi.nlm.nih.gov/gene/424025", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR005821", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005821", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041491", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041491", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050927", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050927", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056336", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056336", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057366", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057366", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:424025", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424025", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CCKNESK", "url": "https://omabrowser.org/oma/group/CCKNESK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YA60", "url": "https://www.orthodb.org/?gene=A0A8V0YA60", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YGF8", "url": "https://www.orthodb.org/?gene=A0A8V0YGF8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YIG0", "url": "https://www.orthodb.org/?gene=A0A8V0YIG0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YIG5", "url": "https://www.orthodb.org/?gene=A0A8V0YIG5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YIH0", "url": "https://www.orthodb.org/?gene=A0A8V0YIH0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YNB4", "url": "https://www.orthodb.org/?gene=A0A8V0YNB4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13800", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13800", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13800:SF9", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13800:SF9", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00520", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00520", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF18139", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18139", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23317", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23317", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25508", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25508", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-3295583", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3295583", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001007083", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001007083", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YA60", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YA60", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YA60-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YA60-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YGF8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGF8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YGF8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGF8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YIG0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIG0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YIG0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIG0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YIG5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIG5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YIG5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIG5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YIH0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIH0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YIH0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIH0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YNB4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNB4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YNB4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNB4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQSVVSTGTMRHRRNGNFESSRLLNSSISRSIDVSCNDSDLVNFIRENFKKRECVFFTKDSNSVGNLCKCGYPESQHIEGTQINDDEKWNYRKHTKELPTDAFGDVHFENIEKRGKYIRLSCDTDPETLYDLMTQHWHLKTPNLVISVTGGAKNFALKPRMRKIFSRLIYIAQSKGAWIFTGGTHNGLMKYIGEVVRDNTISQSSEESVVAIGIAAWGMISNRESLIRSSDNEGYYLAHYIMDDLKRDPLYCLDNNHTHLLLVDNGTHGHPTIEAEVRTQLEKYISERVIPESNYGGKIPIVCFAQGGGKETLKSIHVAIKSKIPCVVVEGSGRIADVIASLMEAEDTLTSSCVKESLHRYLPRTISRLSEEETESWVKWIKEVLENPHLLTVIKTEEAGDEIVSNAIAFALYKAFSTNERNRDNWNEQLKLLLEWNQLDLASDEIFTNDRNWESADLQDVMFTALVKDRPKFVRLFLENGLNLRKFLTTEVLRELYTNNFSSLVFKNLQIAKNSYNDALLTFVWKMVEDFRRGLKRDDKNNKHELEIHLSTECPITRHPLQALFIWSVLQNKKELSKVIWEQTRGCTLAALGASKLLKSMAKVKNDINAAGESEELANEYETRAVELFTECYSNDENLAEQLLTYSCEAWGGSNCLELAVEAKDQQFIAQPGVQNFLSKQWYGGISRDTNNWKIILCLFFFPLIGCGFISFRKKPVEKSKKLFLYYVSFFTSPFVVFSWNVIFYIVFLLLFAYVLLMDFQKEPTVLEIILYVLVFILLCDEVRQWYMNGSKYLSDLWNVMDTLAIFYFIAGIVLRLHSSNESSWYSGRVIFCLDYIVFTLRLIHIFTVSRNLGPKIIMLQRMMIDVFFFLFLFAVWMVAFGVARQGILRKNEHRWEWIFRSVIYEPYLAMFGQYPDDVDGTTYNFDRCTFSGNESKPLCVELDANNQPRFPEWITIPLVCIYMLSTNILLVNLLVAMFGYTVGSVQENNDQVWKFQRYFLVQEYCSRLTIPFPFVIFAYIFMVMRKCFKCCCKNESKEPSICCSRNEDNETLSWEAVMKENYLVKINTKASDTSEEMVHRFRQLDAKLSDLKGLLKEISSKIK", "length": 1104, "header": "tr|A0A8V0YGF8-1|A0A8V0YGF8_CHICK Isoform 1 of Transient receptor potential cation channel subfamily M member 8 OS=Gallus gallus OX=9031 GN=TRPM8 PE=4 SV=1 CANONICAL=A0A8V0YGF8-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YA60-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGF8/entry#A0A8V0YA60-1", "sequence": { "sequence": "MRHRRNGNFESSRLLNSSISRSIDVSCNDSDLVNFIRENFKKRECVFFTKDSNSVGNLCKCGYPESQHIEGTQINDDEKWNYRKHTKELPTDAFGDVHFENIEKRGKYIRLSCDTDPETLYDLMTQHWHLKTPNLVISVTGGAKNFALKPRMRKIFSRLIYIAQSKGAWIFTGGTHNGLMKYIGEVVRDNTISQSSEESVVAIGIAAWGMISNRESLIRSSDNEGYYLAHYIMDDLKRDPLYCLDNNHTHLLLVDNGTHGHPTIEAEVRTQLEKYISERVIPESNYGGKIPIVCFAQGGGKETLKSIHVAIKSKIPCVVVEGSGRIADVIASLMEAEDTLTSSCVKESLHRYLPRTISRLSEEETESWVKWIKEVLENPHLLTVIKTEEAGDEIVSNAIAFALYKAAFSTNERNRDNWNEQLKLLLEWNQLDLASDEIFTNDRNWESADLQDVMFTALVKDRPKFVRLFLENGLNLRKFLTTEVLRELYTNNFSSLVFKNLQIAKNSYNDALLTFVWKMVEDFRRGLKRDDKNNKHELEIHLSTECPITRHPLQALFIWSVLQNKKELSKVIWEQTRGCTLAALGASKLLKSMAKVKNDINAAGESEELANEYETRAVELFTECYSNDENLAEQLLTYSCEAWGGSNCLELAVEAKDQQFIAQPGVQNFLSKQWYGGISRDTNNWKIILCLFFFPLIGCGFISFRKKPVEKSKKLFLYYVSFFTSPFVVFSWNVIFYIVFLLLFAYVLLMDFQKEPTVLEIILYVLVFILLCDEVRQWYMNGSKYLSDLWNVMDTLAIFYFIAGIVLRLHSSNESSWYSGRVIFCLDYIVFTLRLIHIFTVSRNLGPKIIMLQRMMIDVFFFLFLFAVWMVAFGVARQGILRKNEHRWEWIFRSVIYEPYLAMFGQYPDDVDGTTYNFDRCTFSGNESKPLCVELDANNQPRFPEWITIPLVCIYMLSTNILLVNLLVAMFGYTVGSVQENNDQVWKFQRYFLVQEYCSRLTIPFPFVIFAYIFMVMRKCFKCCCKNESKEPSICCSRNEDNETLSWEAVMKENYLVKINTKASDTSEEMVHRFRQLDAKLSDLKGLLKEISSKIK", "length": 1096, "header": "tr|A0A8V0YA60-1|A0A8V0YA60_CHICK Computationally mapped isoform of Transient receptor potential cation channel subfamily M member 8 OS=Gallus gallus OX=9031 GN=TRPM8 PE=4 SV=1 CANONICAL=A0A8V0YGF8-1" }, "locus": { "chromosome": "7", "start_pos": 5667772, "end_pos": 5637952, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030361.1", "url": "https://www.ensembl.org/id/ENSGALT00010030361.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017613.1", "url": "https://www.ensembl.org/id/ENSGALP00010017613.1" } ] } }, { "isoform_ac": "A0A8V0YGF8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGF8/entry#A0A8V0YGF8-1", "sequence": { "sequence": "MQSVVSTGTMRHRRNGNFESSRLLNSSISRSIDVSCNDSDLVNFIRENFKKRECVFFTKDSNSVGNLCKCGYPESQHIEGTQINDDEKWNYRKHTKELPTDAFGDVHFENIEKRGKYIRLSCDTDPETLYDLMTQHWHLKTPNLVISVTGGAKNFALKPRMRKIFSRLIYIAQSKGAWIFTGGTHNGLMKYIGEVVRDNTISQSSEESVVAIGIAAWGMISNRESLIRSSDNEGYYLAHYIMDDLKRDPLYCLDNNHTHLLLVDNGTHGHPTIEAEVRTQLEKYISERVIPESNYGGKIPIVCFAQGGGKETLKSIHVAIKSKIPCVVVEGSGRIADVIASLMEAEDTLTSSCVKESLHRYLPRTISRLSEEETESWVKWIKEVLENPHLLTVIKTEEAGDEIVSNAIAFALYKAFSTNERNRDNWNEQLKLLLEWNQLDLASDEIFTNDRNWESADLQDVMFTALVKDRPKFVRLFLENGLNLRKFLTTEVLRELYTNNFSSLVFKNLQIAKNSYNDALLTFVWKMVEDFRRGLKRDDKNNKHELEIHLSTECPITRHPLQALFIWSVLQNKKELSKVIWEQTRGCTLAALGASKLLKSMAKVKNDINAAGESEELANEYETRAVELFTECYSNDENLAEQLLTYSCEAWGGSNCLELAVEAKDQQFIAQPGVQNFLSKQWYGGISRDTNNWKIILCLFFFPLIGCGFISFRKKPVEKSKKLFLYYVSFFTSPFVVFSWNVIFYIVFLLLFAYVLLMDFQKEPTVLEIILYVLVFILLCDEVRQWYMNGSKYLSDLWNVMDTLAIFYFIAGIVLRLHSSNESSWYSGRVIFCLDYIVFTLRLIHIFTVSRNLGPKIIMLQRMMIDVFFFLFLFAVWMVAFGVARQGILRKNEHRWEWIFRSVIYEPYLAMFGQYPDDVDGTTYNFDRCTFSGNESKPLCVELDANNQPRFPEWITIPLVCIYMLSTNILLVNLLVAMFGYTVGSVQENNDQVWKFQRYFLVQEYCSRLTIPFPFVIFAYIFMVMRKCFKCCCKNESKEPSICCSRNEDNETLSWEAVMKENYLVKINTKASDTSEEMVHRFRQLDAKLSDLKGLLKEISSKIK", "length": 1104, "header": "tr|A0A8V0YGF8-1|A0A8V0YGF8_CHICK Isoform 1 of Transient receptor potential cation channel subfamily M member 8 OS=Gallus gallus OX=9031 GN=TRPM8 PE=4 SV=1 CANONICAL=A0A8V0YGF8-1" }, "locus": { "chromosome": "7", "start_pos": 5667772, "end_pos": 5634619, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030351.1", "url": "https://www.ensembl.org/id/ENSGALT00010030351.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017605.1", "url": "https://www.ensembl.org/id/ENSGALP00010017605.1" } ] } }, { "isoform_ac": "A0A8V0YIG0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGF8/entry#A0A8V0YIG0-1", "sequence": { "sequence": "MRHRRNGNFESSRLLNSSISRSIDVSCNDSDLVNFIRENFKKRECVFFTKDSNSVGNLCKCGYPESQHIEGTQINDDEKWNYRKHTKELPTDAFGDVHFENIEKRGKYIRLSCDTDPETLYDLMTQHWHLKTPNLVISVTGGAKNFALKPRMRKIFSRLIYIAQSKGAWIFTGGTHNGLMKYIGEVVRDNTISQSSEESVVAIGIAAWGMISNRESLIRSSDNEGYYLAHYIMDDLKRDPLYCLDNNHTHLLLVDNGTHGHPTIEAEVRTQLEKYISERVIPESNYGGKIPIVCFAQGGGKETLKSIHVAIKSKIPCVVVEGSGRIADVIASLMEAEDTLTSSCVKESLHRYLPRTISRLSEEETESWVKWIKEVLENPHLLTVIKTEEAGDEIVSNAIAFALYKEDCSSSAAFSTNERNRDNWNEQLKLLLEWNQLDLASDEIFTNDRNWESADLQDVMFTALVKDRPKFVRLFLENGLNLRKFLTTEVLRELYTNNFSSLVFKNLQIAKNSYNDALLTFVWKMVEDFRRGLKRDDKNNKHELEIHLSTECPITRHPLQALFIWSVLQNKKELSKVIWEQTRGCTLAALGASKLLKSMAKVKNDINAAGESEELANEYETRAVELFTECYSNDENLAEQLLTYSCEAWGGSNCLELAVEAKDQQFIAQPGVQNFLSKQWYGGISRDTNNWKIILCLFFFPLIGCGFISFRKKPVEKSKKLFLYYVSFFTSPFVVFSWNVIFYIVFLLLFAYVLLMDFQKEPTVLEIILYVLVFILLCDEVRQWYMNGSKYLSDLWNVMDTLAIFYFIAGIVLRLHSSNESSWYSGRVIFCLDYIVFTLRLIHIFTVSRNLGPKIIMLQRMMIDVFFFLFLFAVWMVAFGVARQGILRKNEHRWEWIFRSVIYEPYLAMFGQYPDDVDGTTYNFDRCTFSGNESKPLCVELDANNQPRFPEWITIPLVCIYMLSTNILLVNLLVAMFGYTVGSVQENNDQVWKFQRYFLVQEYCSRLTIPFPFVIFAYIFMVMRKCFKCCCKNESKEPSICCSRNEDNETLSWEAVMKENYLVKINTKASDTSEEMVHRFRQLDAKLSDLKGLLKEISSKIK", "length": 1102, "header": "tr|A0A8V0YIG0-1|A0A8V0YIG0_CHICK Computationally mapped isoform of Transient receptor potential cation channel subfamily M member 8 OS=Gallus gallus OX=9031 GN=TRPM8 PE=4 SV=1 CANONICAL=A0A8V0YGF8-1" }, "locus": { "chromosome": "7", "start_pos": 5667772, "end_pos": 5637952, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030328.1", "url": "https://www.ensembl.org/id/ENSGALT00010030328.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017591.1", "url": "https://www.ensembl.org/id/ENSGALP00010017591.1" } ] } }, { "isoform_ac": "A0A8V0YIG5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGF8/entry#A0A8V0YIG5-1", "sequence": { "sequence": "MQLCMCQGTMRHRRNGNFESSRLLNSSISRSIDVSCNDSDLVNFIRENFKKRECVFFTKDSNSVGNLCKCGYPESQHIEGTQINDDEKWNYRKHTKELPTDAFGDVHFENIEKRGKYIRLSCDTDPETLYDLMTQHWHLKTPNLVISVTGGAKNFALKPRMRKIFSRLIYIAQSKGAWIFTGGTHNGLMKYIGEVVRDNTISQSSEESVVAIGIAAWGMISNRESLIRSSDNEGYYLAHYIMDDLKRDPLYCLDNNHTHLLLVDNGTHGHPTIEAEVRTQLEKYISERVIPESNYGGKIPIVCFAQGGGKETLKSIHVAIKSKIPCVVVEGSGRIADVIASLMEAEDTLTSSCVKESLHRYLPRTISRLSEEETESWVKWIKEVLENPHLLTVIKTEEAGDEIVSNAIAFALYKEDCSSSAAFSTNERNRDNWNEQLKLLLEWNQLDLASDEIFTNDRNWESADLQDVMFTALVKDRPKFVRLFLENGLNLRKFLTTEVLRELYTNNFSSLVFKNLQIAKNSYNDALLTFVWKMVEDFRRGLKRDDKNNKHELEIHLSTECPITRHPLQALFIWSVLQNKKELSKVIWEQTRGCTLAALGASKLLKSMAKVKNDINAAGESEELANEYETRAVELFTECYSNDENLAEQLLTYSCEAWGGSNCLELAVEAKDQQFIAQPGVQNFLSKQWYGGISRDTNNWKIILCLFFFPLIGCGFISFRKKPVEKSKKLFLYYVSFFTSPFVVFSWNVIFYIVFLLLFAYVLLMDFQKEPTVLEIILYVLVFILLCDEVRQWYMNGSKYLSDLWNVMDTLAIFYFIAGIVLRLHSSNESSWYSGRVIFCLDYIVFTLRLIHIFTVSRNLGPKIIMLQRMMIDVFFFLFLFAVWMVAFGVARQGILRKNEHRWEWIFRSVIYEPYLAMFGQYPDDVDGTTYNFDRCTFSGNESKPLCVELDANNQPRFPEWITIPLVCIYMLSTNILLVNLLVAMFGYTVGSVQENNDQVWKFQRYFLVQEYCSRLTIPFPFVIFAYIFMVMRKCFKCCCKNESKEPSICCSRNEDNETLSWEAVMKENYLVKINTKASDTSEEMVHRFRQLDAKLSDLKGLLKEISSKIK", "length": 1111, "header": "tr|A0A8V0YIG5-1|A0A8V0YIG5_CHICK Computationally mapped isoform of Transient receptor potential cation channel subfamily M member 8 OS=Gallus gallus OX=9031 GN=TRPM8 PE=4 SV=1 CANONICAL=A0A8V0YGF8-1" }, "locus": { "chromosome": "7", "start_pos": 5667772, "end_pos": 5634901, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030333.1", "url": "https://www.ensembl.org/id/ENSGALT00010030333.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017596.1", "url": "https://www.ensembl.org/id/ENSGALP00010017596.1" } ] } }, { "isoform_ac": "A0A8V0YIH0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGF8/entry#A0A8V0YIH0-1", "sequence": { "sequence": "MRHRRNGNFESSRLLNSSISRSIDVSCNDSDLVNFIRENFKKRECVFFTKDSNSVGNLCKCGYPESQHIEGTQINDDEKWNYRKHTKELPTDAFGDVHFENIEKRGKYIRLSCDTDPETLYDLMTQHWHLKTPNLVISVTGGAKNFALKPRMRKIFSRLIYIAQSKGAWIFTGGTHNGLMKYIGEVVRDNTISQSSEESVVAIGIAAWGMISNRESLIRSSDNEGYYLAHYIMDDLKRDPLYCLDNNHTHLLLVDNGTHGHPTIEAEVRTQLEKYISERVIPESNYGGKIPIVCFAQGGGKETLKSIHVAIKSKIPCVVVEGSGRIADVIASLMEAEDTLTSSCVKESLHRYLPRTISRLSEEETESWVKWIKEVLENPHLLTVIKTEEAGDEIVSNAIAFALYKEDCSSSAAFSTNERNRDNWNEQLKLLLEWNQLDLASDEIFTNDRNWESADLQDVMFTALVKDRPKFVRLFLENGLNLRKFLTTEVLRELYTNNFSSLVFKNLQIAKNSYNDALLTFVWKMVEDFRRGLKRDDKNNKHELEIHLSTECPITRHPLQALFIWSVLQNKKELSKVIWEQTRGCTLAALGASKLLKSMAKVKNDINAAGESEELANEYETRAVELFTECYSNDENLAEQLLTYSCEAWGGSNCLELAVEAKDQQFIAQPGVQWYMNGSKYLSDLWNVMDTLAIFYFIAGIVLRLHSSNESSWYSGRVIFCLDYIVFTLRLIHIFTVSRNLGPKIIMLQRMMIDVFFFLFLFAVWMVAFGVARQGILRKNEHRWEWIFRSVIYEPYLAMFGQYPDDVDGTTYNFDRCTFSGNESKPLCVELDANNQPRFPEWITIPLVCIYMLSTNILLVNLLVAMFGYTVGSVQENNDQVWKFQRYFLVQEYCSRLTIPFPFVIFAYIFMVMRKCFKCCCKNESKEPSICCSRNEDNETLSWEAVMKENYLVKINTKASDTSEEMVHRFRQLDAKLSDLKGLLKEISSKIK", "length": 992, "header": "tr|A0A8V0YIH0-1|A0A8V0YIH0_CHICK Computationally mapped isoform of Transient receptor potential cation channel subfamily M member 8 OS=Gallus gallus OX=9031 GN=TRPM8 PE=4 SV=1 CANONICAL=A0A8V0YGF8-1" }, "locus": { "chromosome": "7", "start_pos": 5667772, "end_pos": 5637952, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030344.1", "url": "https://www.ensembl.org/id/ENSGALT00010030344.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017601.1", "url": "https://www.ensembl.org/id/ENSGALP00010017601.1" } ] } }, { "isoform_ac": "A0A8V0YNB4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGF8/entry#A0A8V0YNB4-1", "sequence": { "sequence": "MEKVNQLDTKPQRKENGAMQSVVSTGTMRHRRNGNFESSRLLNSSISRSIDVSCNDSDLVNFIRENFKKRECVFFTKDSNSVGNLCKCGYPESQHIEGTQINDDEKWNYRKHTKELPTDAFGDVHFENIEKRGKYIRLSCDTDPETLYDLMTQHWHLKTPNLVISVTGGAKNFALKPRMRKIFSRLIYIAQSKGAWIFTGGTHNGLMKYIGEVVRDNTISQSSEESVVAIGIAAWGMISNRESLIRSSDNEGYYLAHYIMDDLKRDPLYCLDNNHTHLLLVDNGTHGHPTIEAEVRTQLEKYISERVIPESNYGGKIPIVCFAQGGGKETLKSIHVAIKSKIPCVVVEGSGRIADVIASLMEAEDTLTSSCVKESLHRYLPRTISRLSEEETESWVKWIKEVLENPHLLTVIKTEEAGDEIVSNAIAFALYKEDCSSSAAFSTNERNRDNWNEQLKLLLEWNQLDLASDEIFTNDRNWESADLQDVMFTALVKDRPKFVRLFLENGLNLRKFLTTEVLRELYTNNFSSLVFKNLQIAKNSYNDALLTFVWKMVEDFRRGLKRDDKNNKHELEIHLSTECPITRHPLQALFIWSVLQNKKELSKVIWEQTRGCTLAALGASKLLKSMAKVKNDINAAGESEELANEYETRAVELFTECYSNDENLAEQLLTYSCEAWGGSNCLELAVEAKDQQFIAQPGVQNFLSKQWYGGISRDTNNWKIILCLFFFPLIGCGFISFRKKPVEKSKKLFLYYVSFFTSPFVVFSWNVIFYIVFLLLFAYVLLMDFQKEPTVLEIILYVLVFILLCDEVRQWYMNGSKYLSDLWNVMDTLAIFYFIAGIVLRLHSSNESSWYSGRVIFCLDYIVFTLRLIHIFTVSRNLGPKIIMLQRMMIDVFFFLFLFAVWMVAFGVARQGILRKNEHRWEWIFRSVIYEPYLAMFGQYPDDVDGTTYNFDRCTFSGNESKPLCVELDANNQPRFPEWITIPLVCIYMLSTNILLVNLLVAMFGYTVGSVQENNDQVWKFQRYFLVQEYCSRLTIPFPFVIFAYIFMVMRKCFKCCCKNESKEPSICCSRNEDNETLSWEAVMKENYLVKINTKASDTSEEMVHRFRQLDAKLSDLKGLLKEISSKIK", "length": 1129, "header": "tr|A0A8V0YNB4-1|A0A8V0YNB4_CHICK Computationally mapped isoform of Transient receptor potential cation channel subfamily M member 8 OS=Gallus gallus OX=9031 GN=TRPM8 PE=4 SV=1 CANONICAL=A0A8V0YGF8-1" }, "locus": { "chromosome": "7", "start_pos": 5667772, "end_pos": 5601882, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030356.1", "url": "https://www.ensembl.org/id/ENSGALT00010030356.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017609.1", "url": "https://www.ensembl.org/id/ENSGALP00010017609.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Two different avian cold-sensitive sensory neurons: Transient receptor potential melastatin 8 (TRPM8)-dependent and -independent activation mechanisms.", "journal": "Neuropharmacology", "date": "2016-12", "authors": "Yamamoto A, Takahashi K, Saito S, Tominaga M, Ohta T", "evidence": [ { "database": "RefSeq", "id": "NP_001007083", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001007083" } ], "reference": [ { "type": "PubMed", "id": "27590914", "url": "https://glygen.org/publication/PubMed/27590914" } ] }, { "title": "The effects of neuronal cell differentiation on TRPM7, TRPM8 and TRPV1 channels in the model of Parkinson's disease.", "journal": "Neurological research", "date": "2022-01", "authors": "\u00d6z Ahmi, \u00c7elik \u00d6mer", "evidence": [ { "database": "RefSeq", "id": "NP_001007083", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001007083" } ], "reference": [ { "type": "PubMed", "id": "34256685", "url": "https://glygen.org/publication/PubMed/34256685" } ] } ], "pathway": [ { "id": "gga:424025", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424025", "resource": "KEGG Pathway" }, { "id": "R-GGA-3295583", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3295583", "resource": "Reactome", "description": "TRP channels" } ], "orthologs": [ { "uniprot_canonical_ac": "E1BPC8-1", "protein_name": "Transient receptor potential cation channel subfamily M member 8", "gene_name": "TRPM8", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSFKGARFSMRNRRNGTPDSTRTLYSSASRSTDVSYAESDLVNFIEANFKKRECVFFTKDSKATENVCKCGYAQNQHIEGTQINQNEKWNYKKHTKEFPTDAFGDVQFETQGKKGKYIRLSCDTDAETLYELLTQHWHLKTPNLVISVTGGARNFALKPRMRKIFSRLIYIAQSKGAWILTGGTHYGLMKFIGEVVRDNTISRNSEENIVAIGIAAWGMVSNRDTLIRNCDVEGYFSAQYIMDDFKRDPLYILDNNHTHLLLVDNGCHGHPTVEAKLRNQLEKYISERTIQDSNYGGKIPIVCFAQGGGKETLKAINTSVKSKIPCVVVEGSGQIADVIASLVEVEDVLTSSIIKEKLVRFLPRTVSRLPEEETESWIRWLKEIVESSHLLTVIKMEEAGDEIVSNAISYALYKAFSTNEQDKDNWNGQLKLLLEWNQLDIANDEIFTNDRRWESADLQEVMFTALIKDRPKFVRLFLENGLNLRKFLTNDVLTELFSNHFSSLVYRNLQIAKNSYNDALLTFVWKLVANFRRGFRKEDRNSRDEIDIELHDVSPITRHPLQALFIWAILQNKKELSKVIWEQTRGCTLAALGASKLLKTLAKVKNDINAAGESEELANEYETRAVELFTECYSSDEDLAEQLLVYSCEAWGGSSCLELAVEATDQHFIAQPGVQNFLSKQWYGEISRDTKNWKIILCLFIIPLVGCGFVSFRKKPLDKHRRLLWYYVAFFTSPFVVFSWNVVFYIAFLLLFAYVLLMDFHSVPHAPELVLYALVFVLFCDEVRQWCVNGVNYFTDLWNVMDSLGLFYFIAGIVFRLHPANKTSLYSGRVIFCLDYIIFTLRLIHIFTVSRNLGPKIIMLQRMLIDVFFFLFLFAVWMVAFGVARQGILRQNEHRWRWIFRSVIYEPYLAMFGQVPSDVDGTTYDFSHCTFTGNESKPLCVELDEHNLPRFPEWITIPLVCIYMLSTNILLVNLLVAMFGYTVGTVQENNDQVWKFQRYFLVQEYCSRLNIPFPFVVFAYFYKVAKKCFRCCCKERSTEPSACCFRNEDNMTLAWEGVMKENYLVKINTKASDPSEEIRHRFRQLDTKLNDLKGILKEIANKIK", "length": 1104 }, "evidence": [ { "id": "A0A8V0YGF8", "url": "https://omabrowser.org/oma/group/A0A8V0YGF8/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q7Z2W7-1", "protein_name": "Transient receptor potential cation channel subfamily M member 8", "gene_name": "TRPM8", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": 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"https://www.uniprot.org/uniprotkb/A0A8V0YGF8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGF8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGF8" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGF8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGF8" } ], "pmid": "" }, { "name": "membrane raft", "id": "GO:0045121", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045121", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGF8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGF8" } ], "pmid": "" }, { "name": "external side of plasma membrane", "id": "GO:0009897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009897", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGF8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGF8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "monoatomic cation transmembrane transport", "id": "GO:0098655", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098655", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGF8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGF8" } ], "pmid": "" }, { "name": "calcium ion transmembrane transport", "id": "GO:0070588", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070588", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGF8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGF8" } ], "pmid": "" }, { "name": "positive regulation of cold-induced thermogenesis", "id": "GO:0120162", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120162", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGF8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGF8" } ], "pmid": "" }, { "name": "thermoception", "id": "GO:0050955", 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"start_pos": 256, "end_pos": 258 }, { "start_pos": 25, "end_pos": 27 }, { "start_pos": 265, "end_pos": 267 }, { "start_pos": 37, "end_pos": 39 }, { "start_pos": 500, "end_pos": 502 }, { "start_pos": 789, "end_pos": 791 }, { "start_pos": 821, "end_pos": 823 }, { "start_pos": 934, "end_pos": 936 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", 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0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8V0YGF9-1", "uniprot_ac": "A0A8V0YGF9", "uniprot_id": "A0A8V0YGF9_CHICK", "mass": { "chemical_mass": 75583.0, "monoisotopic_mass": 75583.0 }, "refseq": { "ac": "XP_015140050", "name": "zinc finger and BTB domain-containing protein 24 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015140050" }, "gene_names": [ { "name": "ZBTB24", "type": "recommended", "evidence": [ { "id": "A0A8V0YGF9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGF9" } ] }, { "name": "ZBTB24", "type": "synonym", "evidence": [ { "id": "XP_015140050", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015140050" } ] } ], "protein_names": [ { "name": "Zinc finger and BTB domain-containing protein 24", "type": "recommended", "evidence": [ { "id": "A0A8V0YGF9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGF9/entry#names_and_taxonomy" } ] }, { "name": "Zinc finger protein 450", "type": "synonym", "evidence": [ { "id": "A0A8V0YGF9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGF9/entry#names_and_taxonomy" } ] }, { "name": "zinc finger and BTB domain-containing protein 24 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015140050", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015140050" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052534.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015140050.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015140050", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015140050" } ] }, { "annotation": "May be involved in BMP2-induced transcription.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGF9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGF9#function" }, { "database": "UniProtKB", "id": "ARBA00056876", "url": "https://www.uniprot.org/uniprotkb/ARBA00056876#function" } ] }, { "annotation": "May be involved in transcriptional regulation.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGF9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGF9#function" }, { "database": "UniProtKB", "id": "ARBA00003767", "url": "https://www.uniprot.org/uniprotkb/ARBA00003767#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGF9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGF9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ZBTB24", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGF9", "locus": { "chromosome": "3", "start_pos": 66616005, "end_pos": 66608159, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010014135", "url": "https://www.ensembl.org/id/ENSGALG00010014135" } ] } } ], "crossref": [ { "id": "A0A8V0YGF9", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YGF9", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd18212", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18212", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "421763", "url": "https://www.ncbi.nlm.nih.gov/gene/421763", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000210", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000210", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011333", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011333", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050457", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050457", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:421763", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:421763", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "SNHHIQG", "url": "https://omabrowser.org/oma/group/SNHHIQG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YGF9", "url": "https://www.orthodb.org/?gene=A0A8V0YGF9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46105", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46105", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46105:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46105:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00651", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00651", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015140050", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015140050", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YGF9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGF9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YGF9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGF9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAEMSPDPSEKLVVIHSKTHKHTILASFEEQRKKDFLCDITLIVENVQFRAHKALLAASSEYFSMMFVDEGEIGQSIYVLEGMVADAFGALLEFIYTGYVHATEKSSEQILATAQLLKVNDLLRAYNEYQAGRSPGDTLPITTNGSTSVALTAGDKKSEELPKRKRGRPRKIHIVQEEKPGANFAEDVQLRENNSMQNKQNSMKKDTAADGIVISEQDLARKDAEETEPAGGSEAATALSAEKDENCDPRSEGMQSAQSRYSKRRLRRSIRLKDYKLLGEEDEKGLAKRTDGKRKRAGSEARCKDCGKVFKYNHFLAIHQRSHTGERPYKCSECGKGFSQKHSLQVHERMHTGERPYTCTVCNKALTTKHSLLEHMSLHTGQKAFTCDQCGKYFSQKRQLKSHYRVHTGRSLPECNQCHRKFMDAAQLKKHLRTHTGEKPFTCEICGKSFTAKSSLQTHIRIHRGEKPYSCGICGKSFSDSSAKRRHCILHTGKKPFSCPECSLQFARLDNLKSHLKIHSKEKQFQEASTAPSTNTNSEEVRNILQLQQYQLATSGGQEIQLLVADAVHNINFMPSHNQGISIVTAESAPNMATGQAANLTLLAQPPQQLQNLLLSAQQEQVEQIQNINVMANQIETAQPEQMHVITLSKEALEHLHAHQGQNEEIHLAGSSHPD", "length": 675, "header": "tr|A0A8V0YGF9-1|A0A8V0YGF9_CHICK Isoform 1 of Zinc finger and BTB domain-containing protein 24 OS=Gallus gallus OX=9031 GN=ZBTB24 PE=3 SV=1 CANONICAL=A0A8V0YGF9-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YGF9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGF9/entry#A0A8V0YGF9-1", "sequence": { "sequence": "MAEMSPDPSEKLVVIHSKTHKHTILASFEEQRKKDFLCDITLIVENVQFRAHKALLAASSEYFSMMFVDEGEIGQSIYVLEGMVADAFGALLEFIYTGYVHATEKSSEQILATAQLLKVNDLLRAYNEYQAGRSPGDTLPITTNGSTSVALTAGDKKSEELPKRKRGRPRKIHIVQEEKPGANFAEDVQLRENNSMQNKQNSMKKDTAADGIVISEQDLARKDAEETEPAGGSEAATALSAEKDENCDPRSEGMQSAQSRYSKRRLRRSIRLKDYKLLGEEDEKGLAKRTDGKRKRAGSEARCKDCGKVFKYNHFLAIHQRSHTGERPYKCSECGKGFSQKHSLQVHERMHTGERPYTCTVCNKALTTKHSLLEHMSLHTGQKAFTCDQCGKYFSQKRQLKSHYRVHTGRSLPECNQCHRKFMDAAQLKKHLRTHTGEKPFTCEICGKSFTAKSSLQTHIRIHRGEKPYSCGICGKSFSDSSAKRRHCILHTGKKPFSCPECSLQFARLDNLKSHLKIHSKEKQFQEASTAPSTNTNSEEVRNILQLQQYQLATSGGQEIQLLVADAVHNINFMPSHNQGISIVTAESAPNMATGQAANLTLLAQPPQQLQNLLLSAQQEQVEQIQNINVMANQIETAQPEQMHVITLSKEALEHLHAHQGQNEEIHLAGSSHPD", "length": 675, "header": "tr|A0A8V0YGF9-1|A0A8V0YGF9_CHICK Isoform 1 of Zinc finger and BTB domain-containing protein 24 OS=Gallus gallus OX=9031 GN=ZBTB24 PE=3 SV=1 CANONICAL=A0A8V0YGF9-1" }, "locus": { "chromosome": "3", "start_pos": 66614662, "end_pos": 66608186, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033942.1", "url": "https://www.ensembl.org/id/ENSGALT00010033942.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019949.1", "url": "https://www.ensembl.org/id/ENSGALP00010019949.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:421763", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:421763", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A9J7FHV6-1", "protein_name": "Zinc finger and BTB domain-containing protein 24", "gene_name": "Zbtb24", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAETTPETSGQLVVHADTHSDTVLASLEDQRKRGFLCDITLIVENVHFRAHKALLAASSEYFSMMFAEEGEIGQSIYMLEGMVADTFGILLEFIYTGYLHASEKTTEQILATAQFLKVYDLIKAYTDFQTNHSSSKPTALNGTGTPVVVISNKKNDPLKRKRGRPRKGNSIQEGKSELAAEEEMQLRVNNSVQNRQNFVDKEGDGVELSEQMPKEKESEPTGEPGRVEEMLAEKDENCDPKALDGQDSLSRYSKRRIRRSVKLKDYKLLGDEDDQCSVKRTCGRKKRASGPEAQCKDCGKVFKYNHFLAIHQRRHTGERPFKCNECGKGFAQKHSLQVHTRMHTGERPYTCTVCSKALTTKHSLLEHMSLHSGQKSFTCDQCGKYFSQKRQLKSHYRVHTGHSLPECNHCHRKFMDVSQLKKHLRTHTGEKPFTCEICGKSFTAKSSLQTHIRIHRGEKPYSCSICGKSFSDSSAKRRHCILHTGKKPFSCPECSLQFARLDNLKAHLKIHSKEKHTSDSSSVSGSNADEVRSILQLQPYQLSTSGEQEIQLLVTDSVHNINFMPGPNEGVSIVAAESSQNMATDPAANLALLTQQPEQLQSLILSAQPEQTEHIQSLSMIGSQMEPSQAEPVQLITLSKETLALAHLHAHQGQTEALRLAADASDPAQHLQLTQEPDPPLPTPLGQEQS", "length": 690 }, "evidence": [ { "id": "A0A8V0YGF9", "url": "https://omabrowser.org/oma/group/A0A8V0YGF9/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "F1RSY1-1", "protein_name": "Zinc finger and BTB domain-containing protein 24", "gene_name": "ZBTB24", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAEISSEPSGQLIVHSDTHSDTVLASFEDQRKKGFLCDITLIVENVHFRAHKALLAASSEYFSMMFAEEGEIGQSIYMLEGMVADTFGILLEFIYTGCLQASEKSTEQILATAQFLKVYDLVKAYADFQNNHSSPKPATLNTAGAPVVVISNKKNEPPKRKRGRPRKVNSLQEGKSELAAEEELQLRVNNSVQNRAHFMVKELDSGVLSEQIPAKELEESEPACEPGRGEEMPAEKDENCDPKSQDGQDSQSRCSKRRIRRSVKLKDYKLVGDEDDQGSARRVCGRRKRPGGPEARCKDCGKVFKYNHFLAIHQRSHTGERPFKCNECGKGFAQKHSLQVHTRMHTGERPYTCTVCGKALTTKHSLLEHMSLHSGQKSFTCDQCGKYFSQKRQLKSHYRVHTGHSLPECNHCHRKFMDVSQLKKHLRTHTGEKPFTCEICGKSFTAKSSLQTHIRIHRGEKPYSCAVCGKSFSDSSAKRRHCILHTGKKPFSCPECNLQFARLDNLKAHLKIHSKEKHVSDASSVSGNSNTEEVRNVLQLQPYQLSTSGEQEIQLLVTDSVHNINFMPGPSQGISIVTAESSQNMTADQAANLTLLAQQPEQLQNLILSAQQEQTEHMQSLNMIESQMEPSQTEPVHVITLSKETLEHLHAHQEQTGQLHLAGASDPAQHLQLTQEPPAHHVPQPTPLSQEQS", "length": 693 }, "evidence": [ { "id": "A0A8V0YGF9", "url": "https://omabrowser.org/oma/group/A0A8V0YGF9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "O43167-1", "protein_name": "Zinc finger and BTB domain-containing protein 24", "gene_name": "ZBTB24", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAETSPEPSGQLVVHSDAHSDTVLASFEDQRKKGFLCDITLIVENVHFRAHKALLAASSEYFSMMFAEEGEIGQSIYMLEGMVADTFGILLEFIYTGYLHASEKSTEQILATAQFLKVYDLVKAYTDFQNNHSSPKPTTLNTAGAPVVVISNKKNDPPKRKRGRPKKVNTLQEEKSELAAEEEIQLRVNNSVQNRQNFVVKGDSGVLNEQIAAKEKEESEPTCEPSREEEMPVEKDENYDPKTEDGQASQSRYSKRRIWRSVKLKDYKLVGDQEDHGSAKRICGRRKRPGGPEARCKDCGKVFKYNHFLAIHQRSHTGERPFKCNECGKGFAQKHSLQVHTRMHTGERPYTCTVCSKALTTKHSLLEHMSLHSGQKSFTCDQCGKYFSQNRQLKSHYRVHTGHSLPECKDCHRKFMDVSQLKKHLRTHTGEKPFTCEICGKSFTAKSSLQTHIRIHRGEKPYSCGICGKSFSDSSAKRRHCILHTGKKPFSCPECNLQFARLDNLKAHLKIHSKEKHASDASSISGSSNTEEVRNILQLQPYQLSTSGEQEIQLLVTDSVHNINFMPGPSQGISIVTAESSQNMTADQAANLTLLTQQPEQLQNLILSAQQEQTEHIQSLNMIESQMGPSQTEPVHVITLSKETLEHLHAHQEQTEELHLATSTSDPAQHLQLTQEPGPPPPTHHVPQPTPLGQEQS", "length": 697 }, "evidence": [ { "id": "A0A8V0YGF9", "url": "https://omabrowser.org/oma/group/A0A8V0YGF9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q3B725-1", "protein_name": "Zinc finger and BTB domain-containing protein 24", "gene_name": "Zbtb24", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MADTTPEPSGHLIVHSDTHSDTVLASLEDQRKKGFLCDITLIVENVHFRAHKALLAASSEYFSMMFAEEGEIGQSIYMLEGMVADTFGILLEFIYTGYLHASEKMTEQILATAQFLKVYDLVKAYTDFQNSHNSPKPPALNCSGTPVVVISNKKNDPLKRKRGRPRKTNSLQEGKSELAAEGEVQLRVNNSVQNRQNFVFKEDSVRLNEQTPKEKELEPAGEPGSVEEMPAEKDENSDPKARDGPGSQSRYSKRRTRRSVKLKDYKLSGDEDDQSTAKRATCGRQKRSSAPEARCKDCDRVFKYSHFLAIHQRRHTGERPFKCSECGKGFAQKHSLQVHTRMHTGERPYTCTVCSKALTTKHSLLEHMSLHSGQKSFTCDQCGKYFSQKRQLKSHYRVHTGHSLPECNHCHRKFMDVSQLKKHLRTHTGEKPFTCEICGKSFTAKSSLQTHIRIHRGEKPYSCSICGKCFSDSSAKRRHCVLHTGKKPFSCPECSLQFARLDNLKAHLKIHSKEKHASDSSSVSGSSADEVRNVLQLQPYQLSASGEQEIQLLVTDSVHNINFMPTPSQGVSIVAAESSQNMATDPAANITLLTQQPEQLQGLILSAQQEQTEHIQSLGMIGSQMDTSQTEPVHVITLSKETLEHLHAHQEQTSSSVPAADTGARASSPPSTRPGAELTQAPLTVPLDPSPGATVGGVALWAVLL", "length": 705 }, "evidence": [ { "id": "A0A8V0YGF9", "url": "https://omabrowser.org/oma/group/A0A8V0YGF9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q52KB5-1", "protein_name": "Zinc finger and BTB domain-containing protein 24", "gene_name": "zbtb24", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSALPPSSSSPAVLALHSATHKDTILHKFDTLRRSELLCDITLIVEDVHFKAHKALLAASSEYFSALFTAEEQVSQSLYKLDGMTANTFSSVLEFMYSAVVLVDESSSEQLMEMARFLVIPDLIKAHEDLQAVDEHMQVKRKRGRPKKNQDLSQKENPESELQAQTSSEIQEVNEEPASPATDGSDGEFNPREERRREGKRKIKQPIRLKGFRMDDLMEGKEPGKRGRRRKYPDTEARCEECGKVFKSHLFLKIHQRTHTGEKPFRCSVCGKEFTQKHTLLVHQRMHTGEKPYICTVCSKALSTKHSLLEHMNLHTENKLFTCEECGKSFSQQRQLKSHNRVHTGKGLPECAECHHKFMDAAQLKKHLRTHTGEKPFTCEICGKCFTAKSTLQTHIRIHRGEKPYVCKVCDKTFSDPSARRRHEVSHTGKKTFSCSICKVSFARKDNLKAHIKTHNKENPPAQAESTDKPPQSAPEQQEQEQQQQQQTSGDKELHSILQLQPFQLPAHGEQEIQLLVTGENLSLDQEQSISIITSEDTEQSLALLTQPSGHVQNLAVVTPDGNAQIQTISVLGGEVNGGDPEQMHVITLSKEAMEQLQVHHGAPQQLQVIHQLSEEQTGPVAGIHISGQSGQAISISQTTEQIPSDQIQGQTFQIQAGTVSYLYTTSMNPQN", "length": 672 }, "evidence": [ { "id": "A0A8V0YGF9", "url": "https://omabrowser.org/oma/group/A0A8V0YGF9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q80X44-1", "protein_name": "Zinc finger and BTB domain-containing protein 24", "gene_name": "Zbtb24", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MADTTPEPCGQLMVHSDTHSDTVLASLEDQRKKGFLCDITLIVENVHFRAHKALLAASSEYFSMMFAEEGEIGQSIYMLEGMVADTFGILLEFIYTGYLHASEKTTEQILATAQFLKVYDLVKAYADFQDNHSAPKPPALNCTGTPVVVISNKKNDPLKRKRGRPRKANGLQEGRSELAAEGELQLRVNNSVQNRQNFVFKEEDSVKLSEQTPEDKESEPAGEPGSVEEVPAEKDENFDPKAGDGQESQSRCSRRRIRRSVKLKDYKLLGDEDDQSTAKRLCGRKKRSSGPEARCKDCDRVFKYSHFLAIHQRRHTGERPFKCNECGKGFAQKHSLQVHTRMHTGERPYTCTVCGKALTTKHSLLEHMSLHSGQKSFTCDQCGKYFSQKRQLKSHYRVHTGHSLPECSHCHRKFMDVSQLKKHLRTHTGEKPFTCEICGKSFTAKSSLQTHIRIHRGEKPYSCSICGKCFSDSSAKRRHCILHTGKKPFSCPECGLQFARLDNLKAHLKIHSKEKHTADSSSVSGSNVDEGRNILQLQPYQLSTSGEQEIQLLVTDSVHNINFMPGPSQGVSIVAAESPQSMATDPAANITLLTQQPEQLQGLILSAQQEQAEHIQSLSVIGGQMESSQTEPVHVITLSKETLEHLHAHQEQTTSSVPAADTGARATPVPSTRPGAELTQAPLAVPLDPSPGATVAGWPFGPSSYRSLKM", "length": 710 }, "evidence": [ { "id": "A0A8V0YGF9", "url": "https://omabrowser.org/oma/group/A0A8V0YGF9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGF9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGF9" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGF9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGF9" } ], "pmid": "" }, { "name": "regulation of immune system process", "id": "GO:0002682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002682", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGF9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGF9" } ], "pmid": "" }, { "name": "regulation of cytokine production", "id": "GO:0001817", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001817", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGF9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGF9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGF9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGF9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGF9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGF9" } ], "pmid": "" }, { "name": "DNA-binding transcription repressor activity, RNA polymerase II-specific", "id": "GO:0001227", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001227", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGF9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGF9" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGF9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGF9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 144, "end_pos": 146, "annotation": "n_glycosylation_sequon" }, { "start_pos": 193, "end_pos": 195, "annotation": "n_glycosylation_sequon" }, { "start_pos": 599, "end_pos": 601, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YGF9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGF9" }, { "id": "PS50097", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50097" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "BTB", "eco_id": "ECO_0000259", "start_pos": 38, "end_pos": 104, "start_aa": "Cys", "end_aa": "Glu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0YGF9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGF9" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 301, "end_pos": 328, "start_aa": "Ala", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 144, "end_pos": 146 }, { "start_pos": 193, "end_pos": 195 }, { "start_pos": 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This record is derived from a genomic sequence (NC_052572.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_001233766.3. 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"https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22042", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR009071", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009071", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036910", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036910", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051356", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051356", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR45789", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45789", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45789:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45789:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00505", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00505", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YGI4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGI4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YGI4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGI4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YML5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YML5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YML5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YML5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YUM9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUM9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YUM9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUM9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSSKRPASPYGEADGEVAMVTSRQKVGEEESDGLPAFHLPLHVSFPNKPHSEEFQPVSLLTQENCGHRTPTSQHNTMEVDGNKAMSSFAPHNSSTSPLKAEEGGRQSGESLSSTALGTPERRKGSLADVVDTLKQRKMEELIKNEPEETPSIEKLLSKDWKDKLLAMGSGNFGEIKGTPESLAEKERQLMGMINQLTSLREQLLAAHDEQKKLAASQIEKQRQQMELAKQQQEQIARQQQQLLQQQHKINLLQQQIQQVQGQLPPLMIPVFPPDQRTLAAAAQQGFLLPPGFSYKAGCSDPYPVQLIPTTMAAAAAATPGLGPLQLQQLYAAQLAAMQVSPGGKIPGISQGNLGAAVSPTSIHTDKSTNSPPPKSKDEVAQPLNLSAKPKTSDGKSPTSPTSPHMPTLRINSGTSSLKSSVPATLASPSARANTIGYLNDHDAVTKAIQEARQMKEQLRREQQVLDGKVAVVNSLGLNNCRTEKDKTTLETLTQQLAVKQSEDGKFSHAMMDFNMSGDSDGSAGVSESRIYRESRGRGSNEPHIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKAMTNLEKQPYYEEQARLSKQHLEKYPDYKYKPRPKRTCLVDGKKLRIGEYKAIMRNRRQEMRQYFNVGQQAQIPIATAGVVYPGAIAMAGMPSPHLPSEHSSVSSSPEPGMPVIQSTYGIKGEEPHIKEEMQTDDVNGEIYDEYDEEEDDPDVDYGSDSENHIAGQAN", "length": 751, "header": "tr|A0A8V0YGI4-1|A0A8V0YGI4_CHICK Isoform 1 of SRY-box 5 OS=Gallus gallus OX=9031 GN=SOX5 PE=4 SV=1 CANONICAL=A0A8V0YGI4-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YGI4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGI4/entry#A0A8V0YGI4-1", "sequence": { "sequence": "MSSKRPASPYGEADGEVAMVTSRQKVGEEESDGLPAFHLPLHVSFPNKPHSEEFQPVSLLTQENCGHRTPTSQHNTMEVDGNKAMSSFAPHNSSTSPLKAEEGGRQSGESLSSTALGTPERRKGSLADVVDTLKQRKMEELIKNEPEETPSIEKLLSKDWKDKLLAMGSGNFGEIKGTPESLAEKERQLMGMINQLTSLREQLLAAHDEQKKLAASQIEKQRQQMELAKQQQEQIARQQQQLLQQQHKINLLQQQIQQVQGQLPPLMIPVFPPDQRTLAAAAQQGFLLPPGFSYKAGCSDPYPVQLIPTTMAAAAAATPGLGPLQLQQLYAAQLAAMQVSPGGKIPGISQGNLGAAVSPTSIHTDKSTNSPPPKSKDEVAQPLNLSAKPKTSDGKSPTSPTSPHMPTLRINSGTSSLKSSVPATLASPSARANTIGYLNDHDAVTKAIQEARQMKEQLRREQQVLDGKVAVVNSLGLNNCRTEKDKTTLETLTQQLAVKQSEDGKFSHAMMDFNMSGDSDGSAGVSESRIYRESRGRGSNEPHIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKAMTNLEKQPYYEEQARLSKQHLEKYPDYKYKPRPKRTCLVDGKKLRIGEYKAIMRNRRQEMRQYFNVGQQAQIPIATAGVVYPGAIAMAGMPSPHLPSEHSSVSSSPEPGMPVIQSTYGIKGEEPHIKEEMQTDDVNGEIYDEYDEEEDDPDVDYGSDSENHIAGQAN", "length": 751, "header": "tr|A0A8V0YGI4-1|A0A8V0YGI4_CHICK Isoform 1 of SRY-box 5 OS=Gallus gallus OX=9031 GN=SOX5 PE=4 SV=1 CANONICAL=A0A8V0YGI4-1" }, "locus": { "chromosome": "1", "start_pos": 66224879, "end_pos": 65972958, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033987.1", "url": "https://www.ensembl.org/id/ENSGALT00010033987.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019974.1", "url": "https://www.ensembl.org/id/ENSGALP00010019974.1" } ] } }, { "isoform_ac": "A0A8V0YML5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGI4/entry#A0A8V0YML5-1", "sequence": { "sequence": "MLTDPDLPQEFERMSSKRPASPYGEADGEVAMVTSRQKVGEEESDGLPAFHLPLHVSFPNKPHSEEFQPVSLLTQENCGHRTPTSQHNTMEVDGNKAMSSFAPHNSSTSPLKAEEGGRQSGESLSSTALGTPERRKGSLADVVDTLKQRKMEELIKNEPEGTPESLAEKERQLMGMINQLTSLREQLLAAHDEQKKLAASQIEKQRQQMELAKQQQEQIARQQQQLLQQQHKINLLQQQIQVQGQLPPLMIPVFPPDQRTLAAAAQQGFLLPPGFSYKAGCSDPYPVQLIPTTMAAAAAATPGLGPLQLQQLYAAQLAAMQVSPGGKIPGISQGNLGAAVSPTSIHTDKSTNSPPPKSKDEVAQPLNLSAKPKTSDGKSPTSPTSPHMPTLRINSGTSSLKSSVPATLASPSARANTIGYLNDHDAVTKAIQEARQMKEQLRREQQVLDGKVAVVNSLGLNNCRTEKDKTTLETLTQQLAVKQSEDGKFSHAMMDFNMSGDSDGSAGVSESRIYRESRGRGSNEPHIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKAMTNLEKQPYYEEQARLSKQHLEKYPDYKYKPRPKRTCLVDGKKLRIGEYKAIMRNRRQEMRQYFNVGQQAQIPIATAGVVYPGAIAMAGMPSPHLPSEHSSVSSSPEPGMPVIQSTYGIKGEEPHIKEEMQTDDVNGEIYDEYDEEEDDPDVDYGSDSENHIAGQAN", "length": 734, "header": "tr|A0A8V0YML5-1|A0A8V0YML5_CHICK Computationally mapped isoform of SRY-box 5 OS=Gallus gallus OX=9031 GN=SOX5 PE=4 SV=1 CANONICAL=A0A8V0YGI4-1" }, "locus": { "chromosome": "1", "start_pos": 66224879, "end_pos": 65936494, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033977.1", "url": "https://www.ensembl.org/id/ENSGALT00010033977.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019968.1", "url": "https://www.ensembl.org/id/ENSGALP00010019968.1" } ] } }, { "isoform_ac": "A0A8V0YUM9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGI4/entry#A0A8V0YUM9-1", "sequence": { "sequence": "MFNCLIIPDLMSSKRPASPYGEADGEVAMVTSRQKVGEEESDGLPAFHLPLHEVDGNKAMSSFAPHNSSTSPLKAEEGGRQSGESLSSTALGTPERRKGSLADVVDTLKQRKMEELIKNEPEETPSIEKLLSKDWKDKLLAMGSGNFGEIKGTPESLAEKERQLMGMINQLTSLREQLLAAHDEQKKLAASQIEKQRQQMELAKQQQEQIARQQQQLLQQQHKINLLQQQIQVQGQLPPLMIPVFPPDQRTLAAAAQQGFLLPPGFSYKAGCSDPYPVQLIPTTMAAAAAATPGLGPLQLQQLYAAQLAAMQVSPGGKIPGISQGNLGAAVSPTSIHTDKSTNSPPPKSKDEVAQPLNLSAKPKTSDGKSPTSPTSPHMPTLRINSGTSSLKSSVPATLASPSARANTIDILSSITSSGYLNDHDAVTKAIQEARQMKEQLRREQQVLDGKVAVVNSLGLNNCRTEKDKTTLETLTQQLAVKQSEDGKFSHAMMDFNMSGDSDGSAGVSESRIYRESRGRGSNEPHIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKAMTNLEKQPYYEEQARLSKQHLEKYPDYKYKPRPKRTCLVDGKKLRIGEYKAIMRNRRQEMRQYFNVGQQAQIPIATAGVVYPGAIAMAGMPSPHLPSEHSSVSSSPEPGMPVIQSTYGIKGEEPHIKEEMQTDDVNGEIYDEYDEEEDDPDVDYGSDSENHIAGQAN", "length": 734, "header": "tr|A0A8V0YUM9-1|A0A8V0YUM9_CHICK Computationally mapped isoform of SRY-box 5 OS=Gallus gallus OX=9031 GN=SOX5 PE=4 SV=1 CANONICAL=A0A8V0YGI4-1" }, "locus": { "chromosome": "1", "start_pos": 66224879, "end_pos": 65972358, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033963.1", "url": "https://www.ensembl.org/id/ENSGALT00010033963.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019960.1", "url": "https://www.ensembl.org/id/ENSGALP00010019960.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 318, "start_aa": "Thr", "end_pos": 318, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr318", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { 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"UniProtKB", "id": "A0A8V0YGI4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGI4" } ], "pmid": "" }, { "name": "positive regulation of chondrocyte differentiation", "id": "GO:0032332", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032332", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGI4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGI4" } ], "pmid": "" }, { "name": "cellular response to transforming growth factor beta stimulus", "id": "GO:0071560", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071560", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGI4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGI4" } ], "pmid": "" }, { "name": "asymmetric neuroblast division", "id": "GO:0055059", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055059", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGI4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGI4" } ], "pmid": "" }, { "name": "positive regulation of mesenchymal stem cell differentiation", "id": "GO:2000741", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000741", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGI4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGI4" } ], "pmid": "" }, { "name": "cell fate commitment", "id": "GO:0045165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045165", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGI4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGI4" } ], "pmid": "" }, { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGI4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGI4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGI4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGI4" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGI4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGI4" } ], "pmid": "" }, { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGI4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGI4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 384, "end_pos": 386, "annotation": "n_glycosylation_sequon" }, { "start_pos": 514, "end_pos": 516, "annotation": "n_glycosylation_sequon" }, { "start_pos": 573, "end_pos": 575, "annotation": "n_glycosylation_sequon" }, { "start_pos": 92, "end_pos": 94, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], 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"chemical_mass": 113641.0, "monoisotopic_mass": 113641.0 }, "refseq": { "ac": "XP_046791458", "name": "pikachurin isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046791458" }, "gene_names": [ { "name": "EGFLAM", "type": "recommended", "evidence": [ { "id": "A0A8V0YHJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHJ2" } ] }, { "name": "EGFLAM", "type": "synonym", "evidence": [ { "id": "XP_046791458", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046791458" } ] } ], "protein_names": [ { "name": "Pikachurin", "type": "recommended", "evidence": [ { "id": "A0A8V0YHJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHJ2/entry#names_and_taxonomy" } ] }, { "name": "EGF-like, fibronectin type-III and laminin G-like domain-containing protein", "type": "synonym", "evidence": [ { "id": "A0A8V0YHJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHJ2/entry#names_and_taxonomy" } ] }, { "name": "pikachurin isoform X1", "type": "synonym", "evidence": [ { "id": "XP_046791458", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046791458" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_059536) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_046791458", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046791458" } ] }, { "annotation": "Involved in both the retinal photoreceptor ribbon synapse formation and physiological functions of visual perception. Plays a key role in the synaptic organization of photoreceptors by mediating transsynaptic interaction between alpha-dystroglycan and GPR179 on the postsynaptic membrane. Necessary for proper bipolar dendritic tip apposition to the photoreceptor ribbon synapse. Promotes matrix assembly and cell adhesiveness.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHJ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHJ2#function" }, { "database": "UniProtKB", "id": "ARBA00059801", "url": "https://www.uniprot.org/uniprotkb/ARBA00059801#function" }, { "database": "UniProtKB", "id": "A0A8V0YHK3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHK3#function" }, { "database": "UniProtKB", "id": "A0A8V0YPE8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPE8#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHJ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHJ2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "EGFLAM", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHJ2", "locus": { "chromosome": "Z", "start_pos": 12544731, "end_pos": 12471307, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012913", "url": "https://www.ensembl.org/id/ENSGALG00010012913" } ] } } ], "crossref": [ { "id": "A0A8V0YHJ2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YHJ2", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00054", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00054", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd00063", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00063", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd00110", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00110", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "427445", "url": "https://www.ncbi.nlm.nih.gov/gene/427445", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000742", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000742", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001791", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001791", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001881", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001881", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003961", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003961", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013032", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013032", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013320", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013320", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036116", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036116", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050372", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050372", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "CGEGTIE", "url": "https://omabrowser.org/oma/group/CGEGTIE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YGJ8", "url": "https://www.orthodb.org/?gene=A0A8V0YGJ8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YHJ2", "url": "https://www.orthodb.org/?gene=A0A8V0YHJ2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YHK3", "url": "https://www.orthodb.org/?gene=A0A8V0YHK3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YPE8", "url": "https://www.orthodb.org/?gene=A0A8V0YPE8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15036", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15036", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15036:SF88", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15036:SF88", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00008", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00008", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00041", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00041", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00054", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00054", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02210", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02210", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12661", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12661", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25016", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25016", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_046791458", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046791458", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YGJ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGJ8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YGJ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGJ8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHJ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHJ2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHJ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHJ2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHK3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHK3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHK3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHK3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YPE8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPE8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YPE8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPE8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEVPGRCRFASLLLLLASCIGCAAAPRRSIPRRQDRLGPPLDILLDSLNCTAFSVQWRMPKQHASTITGYTVFYSEVEGDKAVKQLSHDVPLSLDMLSMGQLEGQAIFEVVIGDLKPGTPHRVSVGAYGWAGKGRPSMPRDVTTLSQDNCMPPAPPYQPQIVVVSDSEVALSWKPGASEGSSPIQYYMVEFIRPDLDSNWTVIREQIQMESMVLKGLLPNTKYQFAVRAANSYGSSPASTPSDVVRTFSSEELGSGSYGHHYITETVTGDDDGFDVDDSDYDIYIEELRPLPAIKGGNRKFLVETKVTPGSSSRLLSRVLTTTSEPTTSTPTTTRPFNTARVTTTRATRRGSMSSAPRLFDLSCDETICSADSFCVNDYDRGGSRCHCNLGKGGETCTEDITIQYPQFYGYSYITFEPLKNSYQTFQITLEFWAESEDGLLLYCGENEHGRGDFMSLAIIRRSIQFRFNCGTGVAVITSENKIKLGNWHSITLFRDGLNGWLRMDNDAPVTGKSQGQYSKITFRTPFYVGGAPSVYWLVRAAGTNRGFQGCVQLLSVNGKMIDMRPWPLGKALSGADVGECSSGICDEASCINSGTCTASKADSYICLCPLGFKGHHCEEAITLAIPQFNESLRSFASTPWPLEPQNYLSFMEFEMTFRPDLETGVLLYSYDTNSKDFLSINMVAGYVEFRFDCGSGTAVIRSEEPVSLGQWHELRVSRTAKNGILQVDKQKPVEGMAEGAFTQIKCSSEIFLGGVPSYDTVKKNSGILRPFTGSIQKIILNDRTIDVKQDFTFGVNLVNAAHPCVGSPCANGGSCVPKKDSYECDCPLGFDGQHCQKECGNYCLNTITEAIEIPQFIGRSYLIYDNPDILKRVSGSRTNVFMRFKTTMKEGLLMWRGDSPMRPNSDFISLGLQEGALIFSYNLGSGIASIVVNGSFSDGRWHRVKAVRDGQSGKVTVDDYGARTGKSPGKMRQLNINGDLYVGGMKEIALHTNRQYLRGLVGCISHLTLSTDYHISLVEDAADGKNINTCGTK", "length": 1034, "header": "tr|A0A8V0YHJ2-1|A0A8V0YHJ2_CHICK Isoform 1 of Pikachurin OS=Gallus gallus OX=9031 GN=EGFLAM PE=1 SV=1 CANONICAL=A0A8V0YHJ2-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YGJ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHJ2/entry#A0A8V0YGJ8-1", "sequence": { "sequence": "MEVPGRCRFASLLLLLASCIGCAAAPRRSIPRRQDRLGPPLDILLDSLNCTAFSVQWRMPKQHASTITGYTVFYSEVEGDKAVKQLSHDVPLSLDMLSMGQLEGQAIFEVVIGDLKPGTPHRVSVGAYGWAGKGRPSMPRDVTTLSQDNCMPPAPPYQPQIVVVSDSEVALSWKPGASEGSSPIQYYMVEFIRPDLDSNWTVIREQIQMESMVLKGLLPNTKYQFAVRAANSYGSSPASTPSDVVRTFSSEELGSGSYGHHYITETVTGDDDGFDVDDSDYDIYIEELRPLPAIKGGNRKFLVETKVTPGSSSRLLSRVLTTTSEPTTSTPTTTRPFNTARVTTTRATRRGSMSSAPRLFDLSCDETICSADSFCVNDYDRGGSRCHCNLGKGGETCTEDITIQYPQFYGYSYITFEPLKNSYQTFQITLEFWAESEDGLLLYCGENEHGRGDFMSLAIIRRSIQFRFNCGTGVAVITSENKIKLGNWHSITLFRDGLNGWLRMDNDAPVTGKSQGQYSKITFRTPFYVGGAPSVYWLVRAAGTNRGFQGCVQLLSVNGKMIDMRPWPLGKALSGADVAITLAIPQFNESLRSFASTPWPLEPQNYLSFMEFEMTFRPDLETGVLLYSYDTNSKDFLSINMVAGYVEFRFDCGSGTAVIRSEEPVSLGQWHELRVSRTAKNGILQVDKQKPVEGMAEGAFTQIKCSSEIFLGGVPSYDTVKKNSGILRPFTGSIQKIILNDRTIDVKQDFTFGVNLVNAAHPCVGSPCANGGSCVPKKDSYECDCPLGFDGQHCQKAITEAIEIPQFIGRSYLIYDNPDILKRVSGSRTNVFMRFKTTMKEGLLMWRGDSPMRPNSDFISLGLQEGALIFSYNLGSGIASIVVNGSFSDGRWHRVKAVRDGQSGKVTVDDYGARTGKSPGKMRQLNINGDLYVGGMKEIALHTNRQYLRGLVGCISHLTLSTDYHISLVEDAADGKNINTCGTK", "length": 984, "header": "tr|A0A8V0YGJ8-1|A0A8V0YHJ2_CHICK Computationally mapped isoform of Pikachurin OS=Gallus gallus OX=9031 GN=EGFLAM PE=1 SV=1 CANONICAL=A0A8V0YHJ2-1" }, "locus": { "chromosome": "Z", "start_pos": 12543774, "end_pos": 12471602, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031000.1", "url": "https://www.ensembl.org/id/ENSGALT00010031000.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018016.1", "url": "https://www.ensembl.org/id/ENSGALP00010018016.1" } ] } }, { "isoform_ac": "A0A8V0YHJ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHJ2/entry#A0A8V0YHJ2-1", "sequence": { "sequence": "MEVPGRCRFASLLLLLASCIGCAAAPRRSIPRRQDRLGPPLDILLDSLNCTAFSVQWRMPKQHASTITGYTVFYSEVEGDKAVKQLSHDVPLSLDMLSMGQLEGQAIFEVVIGDLKPGTPHRVSVGAYGWAGKGRPSMPRDVTTLSQDNCMPPAPPYQPQIVVVSDSEVALSWKPGASEGSSPIQYYMVEFIRPDLDSNWTVIREQIQMESMVLKGLLPNTKYQFAVRAANSYGSSPASTPSDVVRTFSSEELGSGSYGHHYITETVTGDDDGFDVDDSDYDIYIEELRPLPAIKGGNRKFLVETKVTPGSSSRLLSRVLTTTSEPTTSTPTTTRPFNTARVTTTRATRRGSMSSAPRLFDLSCDETICSADSFCVNDYDRGGSRCHCNLGKGGETCTEDITIQYPQFYGYSYITFEPLKNSYQTFQITLEFWAESEDGLLLYCGENEHGRGDFMSLAIIRRSIQFRFNCGTGVAVITSENKIKLGNWHSITLFRDGLNGWLRMDNDAPVTGKSQGQYSKITFRTPFYVGGAPSVYWLVRAAGTNRGFQGCVQLLSVNGKMIDMRPWPLGKALSGADVGECSSGICDEASCINSGTCTASKADSYICLCPLGFKGHHCEEAITLAIPQFNESLRSFASTPWPLEPQNYLSFMEFEMTFRPDLETGVLLYSYDTNSKDFLSINMVAGYVEFRFDCGSGTAVIRSEEPVSLGQWHELRVSRTAKNGILQVDKQKPVEGMAEGAFTQIKCSSEIFLGGVPSYDTVKKNSGILRPFTGSIQKIILNDRTIDVKQDFTFGVNLVNAAHPCVGSPCANGGSCVPKKDSYECDCPLGFDGQHCQKECGNYCLNTITEAIEIPQFIGRSYLIYDNPDILKRVSGSRTNVFMRFKTTMKEGLLMWRGDSPMRPNSDFISLGLQEGALIFSYNLGSGIASIVVNGSFSDGRWHRVKAVRDGQSGKVTVDDYGARTGKSPGKMRQLNINGDLYVGGMKEIALHTNRQYLRGLVGCISHLTLSTDYHISLVEDAADGKNINTCGTK", "length": 1034, "header": "tr|A0A8V0YHJ2-1|A0A8V0YHJ2_CHICK Isoform 1 of Pikachurin OS=Gallus gallus OX=9031 GN=EGFLAM PE=1 SV=1 CANONICAL=A0A8V0YHJ2-1" }, "locus": { "chromosome": "Z", "start_pos": 12543774, "end_pos": 12471602, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030990.1", "url": "https://www.ensembl.org/id/ENSGALT00010030990.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018009.1", "url": "https://www.ensembl.org/id/ENSGALP00010018009.1" } ] } }, { "isoform_ac": "A0A8V0YHK3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHJ2/entry#A0A8V0YHK3-1", "sequence": { "sequence": "MEVPGRCRFASLLLLLASCIGCAAAPRRSIPRRQDRLGPPLDILLDSLNCTAFSVQWRMPKQHASTITGYTVFYSEVEGDKAVKQLSHDVPLSLDMLSMGQLEGQAIFEVVIGDLKPGTPHRVSVGAYGWAGKGRPSMPRDVTTLSQDNCMPPAPPYQPQIVVVSDSEVALSWKPGASEGSSPIQYYMVEFIRPDLDSNWTVIREQIQMESMVLKGLLPNTKYQFAVRAANSYGSSPASTPSDVVRTFSSEELGSGSYGHHYITETVTGDDDGFDVDDSDYDIYIEELRPLPAIKGGNRKFLVETKVTPGSSSRLLSRVLTTTSEPTTSTPTTTRPFNTARVTTTRATRRGSMSSAPRLFDLSCDETICSADSFCVNDYDRGGSRCHCNLGKGGETCTEDITIQYPQFYGYSYITFEPLKNSYQTFQITLEFWAESEDGLLLYCGENEHGRGDFMSLAIIRRSIQFRFNCGTGVAVITSENKIKLGNWHSITLFRDGLNGWLRMDNDAPVTGKSQGQYSKITFRTPFYVGGAPSVYWLVRAAGTNRGFQGCVQLLSVNGKMIDMRPWPLGKALSGADVGECSSGICDEASCINSGTCTASKADSYICLCPLGFKGHHCEEAITLAIPQFNESLRSFASTPWPLEPQNYLSFMEFEMTFRPDLETGVLLYSYDTNSKDFLSINMVAGYVEFRFDCGSGTAVIRSEEPVSLGQWHELRVSRTAKNGILQVDKQKPVEGMAEGAFTQIKCSSEIFLGGVPSYDTVKKNSGILRPFTGSIQKIILNDRTIDVKQDFTFGVNLVNAAHPCVGSPCANGGSCVPKKDSYECDCPLGFDGQHCQKAITEAIEIPQFIGRSYLIYDNPDILKSYNLGSGIASIVVNGSFSDGRWHRVKAVRDGQSGKVTVDDYGARTGKSPGKMRQLNINGDLYVGGMKEIALHTNRQYLRGLVGCISHLTLSTDYHISLVEDAADGKNINTCGTK", "length": 978, "header": "tr|A0A8V0YHK3-1|A0A8V0YHK3_CHICK Computationally mapped isoform of Pikachurin OS=Gallus gallus OX=9031 GN=EGFLAM PE=1 SV=1 CANONICAL=A0A8V0YHJ2-1" }, "locus": { "chromosome": "Z", "start_pos": 12543774, "end_pos": 12471602, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031003.1", "url": "https://www.ensembl.org/id/ENSGALT00010031003.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018019.1", "url": "https://www.ensembl.org/id/ENSGALP00010018019.1" } ] } }, { "isoform_ac": "A0A8V0YPE8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHJ2/entry#A0A8V0YPE8-1", "sequence": { "sequence": "MEVPGRCRFASLLLLLASCIGCAAAPRRSIPRRQDRLGPPLDILLDSLNCTAFSVQWRMPKQHASTITGYTVFYSEVEGDKAVKQLSHDVPLSLDMLSMGQLEGQAIFEVVIGDLKPGTPHRVSVGAYGWAGKGRPSMPRDVTTLSQDNCMPPAPPYQPQIVVVSDSEVALSWKPGASEGSSPIQYYMVEHMRPDLDSNWTVIREQIQMESMVLKGLLPNTKYQFAVRAANSYGSSPASTPSDVVRTFSSEELGSGSYGHHYITETVTGDDDGFDVDDSDYDIYIEELRPLPAIKGGNRKFLVETKVTPGSSSRLLSRVLTTTSEPTTSTPTTTRPFNTARVTTTRATRRGSMSSAPRLFDLSCDETICSADSFCVNDYDRGGSRCHCNLGKGGETCTEDITIQYPQFYGYSYITFEPLKNSYQTFQITLEFWAESEDGLLLYCGENEHGRGDFMSLAIIRRSIQFRFNCGTGVAVITSENKIKLGNWHSITLFRDGLNGWLRMDNDAPVTGKSQGQYSKITFRTPFYVGGAPSVYWLVRAAGTNRGFQGCVQLLSVNGKMIDMRPWPLGKALSGADVGECSSGICDEASCINSGTCTASKADSYICLCPLGFKGHHCEEAITLAIPQFNESLRSFASTPWPLEPQNYLSFMEFEMTFRPDLETGVLLYSYDTNSKDFLSINMVAGYVEFRFDCGSGTAVIRSEEPVSLGQWHELRVSRTAKNGILQVDKQKPVEGMAEGAFTQIKCSSEIFLGGVPSYDTVKKNSGILRPFTGSIQKIILNDRTIDVKQDFTFGVNLVNAAHPCVGSPCANGGSCVPKKDSYECDCPLGFDGQHCQKAITEAIEIPQFIGRSYLIYDNPDILKRVSGSRTNVFMRFKTTMKEGLLMWRGDSPMRPNSDFISLGLQEGALIFSYNLGSGIASIVVNGSFSDGRWHRVKAVRDGQSGKVTVDDYGARTGKSPGKMRQLNINGDLYVGGMKEIALHTNRQYLRGLVGCISHLTLSTDYHISLVEDAADGKNINTCGTK", "length": 1026, "header": "tr|A0A8V0YPE8-1|A0A8V0YPE8_CHICK Computationally mapped isoform of Pikachurin OS=Gallus gallus OX=9031 GN=EGFLAM PE=1 SV=1 CANONICAL=A0A8V0YHJ2-1" }, "locus": { "chromosome": "Z", "start_pos": 12543774, "end_pos": 12471602, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031012.1", "url": "https://www.ensembl.org/id/ENSGALT00010031012.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018023.1", "url": "https://www.ensembl.org/id/ENSGALP00010018023.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 240, "start_aa": "Thr", "end_pos": 240, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr240", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "B4F785-1", "protein_name": "Pikachurin", "gene_name": "Egflam", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDLISTFLLHFLLLACSLPPGAVSLRTALRKSGKVGPPLDIKLGALNCTAFSIQWKTPKRSGSSIVGYTVFYSELGSDKSLREQSHNVPVGQDTLITEEVIGDLKPGTEYRVSIAAYSQTGKGRLSFPRHVTTLSQDSCLPPEAPHQPHVLVVSDSEVALSWRPGENEGSAPIQSYSVEFIRPDFDKSWTIIQERLQMDSMVIKGLDPDTNYQFAVRAMNAYGFSLRSQPSNTIRTLGPGEAGSGRYGPGYITDTGVSEDDDASEDELDLDVSFEEVKPLPATKVGNKKSKKTSVSNSEMDSRLAQPTSASLPETTVAVPPTPAQRKGKNSVAVMSRLFDMSCDETLCSADSFCVNDYAWGGSRCHCNLGKGGEACSEDIFIQYPQFFGHSYVTFEPLKNSYQAFQITLEFRAEAEDGLLLYCGESEHGRGDFMSLALIRRSLHFRFNCGTGMAIIISETKIKLGAWHSVTLYRDGLNGLLQLNNGTPVTGQSQGQYSKITFRTPLYLGGAPSAYWLVRATGTNRGFQGCVQSLAVNGKKIDMRPWPLGKALNGADVGECSSGICDEASCINGGTCAAIKADSYICLCPLGFRGRHCEDAFTLTIPQFRESLRSYAATPWPLEPQHYLSFTEFEITFRPDSGDGVLLYSYDTSSKDFLSIIMAAGHVEFRFDCGSGTGVLRSEDTLTLGQWHDLRVSRTAKNGILQVDKQKVVEGMAEGGFTQIKCNTDIFIGGVPNYDDVKKNSGILHPFSGSIQKIILNDRTIHVRHDFTSGVNVENAAHPCVGAPCAHGGSCRPRKEGYECDCPLGFEGLNCQKAITEAIEIPQFIGRSYLTYDNPNILKRVSGSRSNAFMRFKTTAKDGLLLWRGDSPMRPNSDFISLGLRDGALVFSYNLGSGVASIMVNGSFSDGRWHRVKAVRDGQSGKITVDDYGARTGKSPGMMRQLNINGALYVGGMKEIALRTNRQYMRGLVGCISHFTLSTDYHISLVEDAVDGKNINTCGAK", "length": 1005 }, "evidence": [ { "id": "A0A8V0YHJ2", "url": "https://omabrowser.org/oma/group/A0A8V0YHJ2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q4VBE4-1", "protein_name": "Pikachurin", "gene_name": "Egflam", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDLISTFSLHFLLLACSLPPGAVSLRTALRKSGKVGPPLDIKLGALNCTAFSIQWKTPKRSGSSIIGYTVFYSEVGSDKSLRERSHNVPVGQDTLITEEVIGDLKPGTEYQVSVAAYSQTGKGRLSFPRHVTTLSQDSCLPPAAPQQPHVLVVSDSEVALSWRPGENEGSAPIQSYSVEFIRPDFDKSWTIIQERLQMDSMVIKGLDPDTNYQFAVKAMNAHGFSPRSWPSNTVRTLGPGEAGSGHYGPGYITNPGVSEDDDGSEDELDLDVSFEEVKPLPATKVGNKKFSVESKKTSVSNSVMGSRLAQPTSASLHETTVAIPPTPAQRKGKNSVAMMSRLFDMSCDETLCSADSFCVNDYAWGGSRCHCNLGKGGEACSEDIFIQYPQFFGHSYVTFEPLKNSYQAFQVTLEFRAEAEDGLLLYCGESEHGRGDFMSLALIRRSLHFRFNCGTGIAIIISETKIKLGAWHTVTLYRDGLNGMLQLNNGTPVTGQSQGQYSKITFRTPLYLGGAPSAYWLVRATGTNRGFQGCVQSLSVNGKKIDMRPWPLGKALNGADVGECSSGICDEASCIHGGTCAAIKADSYICLCPLGFRGRHCEDAFALTIPQFRESLRSYAATPWPLEPQHYLSFTEFEITFRPDSGDGVLLYSYDTGSKDFLSINMAAGHVEFRFDCGSGTGVLRSEAPLTLGQWHDLRVSRTAKNGILQVDKQKVVEGMAEGGFTQIKCNTDIFIGGVPNYDDVKKNSGILHPFSGSIQKIILNDRTIHVKHDFTSGVNVENAAHPCVGAPCAHGGSCRPRKEGYECDCPLGFEGLNCQKECGNHCLNTIIEAIEIPQFIGRSYLTYDNPNILKRVSGSRSNAFMRFKTTAKDGLLLWRGDSPMRPNSDFISLGLRDGALIFSYNLGSGVASIMVNGSFSDGRWHRVKAVRDGQSGKITVDDYGARTGKSPGLMRQLNINGALYVGGMKEIALHTNRQYLRGLVGCISHFTLSTDYHISLVEDAVDGKNINTCGAK", "length": 1017 }, "evidence": [ { "id": "A0A8V0YHJ2", "url": "https://omabrowser.org/oma/group/A0A8V0YHJ2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q63HQ2-1", "protein_name": "Pikachurin", "gene_name": "EGFLAM", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDLIRGVLLRLLLLASSLGPGAVSLRAAIRKPGKVGPPLDIKLGALNCTAFSIQWKMPRHPGSPILGYTVFYSEVGADKSLQEQLHSVPLSRDIPTTEEVIGDLKPGTEYRVSIAAYSQAGKGRLSSPRHVTTLSQDSCLPPAAPQQPHVIVVSDSEVALSWKPGASEGSAPIQYYSVEFIRPDFDKKWTSIHERIQMDSMVIKGLDPDTNYQFAVRAMNSHGPSPRSWPSDIIRTLCPEEAGSGRYGPRYITDMGAGEDDEGFEDDLDLDISFEEVKPLPATKGGNKKFLVESKKMSISNPKTISRLIPPTSASLPVTTVAPQPIPIQRKGKNGVAIMSRLFDMPCDETLCSADSFCVNDYTWGGSRCQCTLGKGGESCSEDIVIQYPQFFGHSYVTFEPLKNSYQAFQITLEFRAEAEDGLLLYCGENEHGRGDFMSLAIIRRSLQFRFNCGTGVAIIVSETKIKLGGWHTVMLYRDGLNGLLQLNNGTPVTGQSQGQYSKITFRTPLYLGGAPSAYWLVRATGTNRGFQGCVQSLAVNGRRIDMRPWPLGKALSGADVGECSSGICDEASCIHGGTCTAIKADSYICLCPLGFKGRHCEDAFTLTIPQFRESLRSYAATPWPLEPQHYLSFMEFEITFRPDSGDGVLLYSYDTGSKDFLSINLAGGHVEFRFDCGSGTGVLRSEDPLTLGNWHELRVSRTAKNGILQVDKQKIVEGMAEGGFTQIKCNTDIFIGGVPNYDDVKKNSGVLKPFSGSIQKIILNDRTIHVKHDFTSGVNVENAAHPCVRAPCAHGGSCRPRKEGYDCDCPLGFEGLHCQKECGNYCLNTIIEAIEIPQFIGRSYLTYDNPDILKRVSGSRSNVFMRFKTTAKDGLLLWRGDSPMRPNSDFISLGLRDGALVFSYNLGSGVASIMVNGSFNDGRWHRVKAVRDGQSGKITVDDYGARTGKSPGMMRQLNINGALYVGGMKEIALHTNRQYMRGLVGCISHFTLSTDYHISLVEDAVDGKNINTCGAK", "length": 1017 }, "evidence": [ { "id": "A0A8V0YHJ2", "url": "https://omabrowser.org/oma/group/A0A8V0YHJ2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHJ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHJ2" } ], "pmid": "" }, { "name": "molecular adaptor activity", "id": "GO:0060090", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060090", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHJ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHJ2" } ], "pmid": "" }, { "name": "glycosaminoglycan binding", "id": "GO:0005539", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005539", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHJ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHJ2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 9, "go_terms": [ { "name": "basement membrane", "id": "GO:0005604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005604", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHJ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHJ2" } ], "pmid": "" }, { "name": "cell projection", "id": "GO:0042995", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042995", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHJ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHJ2" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHJ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHJ2" } ], "pmid": "" }, { "name": "synapse", "id": "GO:0045202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045202", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHJ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHJ2" } ], "pmid": "" }, { "name": "presynaptic active zone", "id": "GO:0048786", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048786", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHJ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHJ2" } ], "pmid": "" }, { "name": "synaptic cleft", "id": "GO:0043083", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043083", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHJ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHJ2" } ], "pmid": "" }, { "name": "interstitial matrix", "id": "GO:0005614", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005614", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHJ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHJ2" } ], "pmid": "" }, { "name": "photoreceptor ribbon synapse", "id": "GO:0098684", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098684", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHJ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHJ2" } ], "pmid": "" }, { "name": "trans-synaptic protein complex", "id": "GO:0098820", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098820", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHJ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHJ2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHJ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHJ2" } ], "pmid": "" }, { "name": "nervous system development", "id": "GO:0007399", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007399", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHJ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHJ2" } ], "pmid": "" }, { "name": "synapse assembly", "id": "GO:0007416", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007416", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHJ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHJ2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 199, "end_pos": 201, "annotation": "n_glycosylation_sequon" }, { "start_pos": 49, "end_pos": 51, "annotation": "n_glycosylation_sequon" }, { "start_pos": 630, "end_pos": 632, "annotation": "n_glycosylation_sequon" }, { "start_pos": 934, "end_pos": 936, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YHJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHJ2" }, { "id": "PS50026", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50026" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "EGF-like", "eco_id": "ECO_0000259", "start_pos": 360, "end_pos": 398, "start_aa": "Phe", "end_aa": "Thr", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0YHJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHJ2" }, { "id": "PS50853", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50853" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Fibronectin type-III", "eco_id": "ECO_0000259", "start_pos": 39, "end_pos": 147, "start_aa": "Pro", "end_aa": "Gln", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0YHJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHJ2" }, { "id": "PS50025", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50025" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Laminin G", "eco_id": "ECO_0000259", "start_pos": 403, "end_pos": 581, "start_aa": "Ile", "end_aa": "Cys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 240 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 199, "end_pos": 201 }, { "start_pos": 49, "end_pos": 51 }, { "start_pos": 630, "end_pos": 632 }, { "start_pos": 934, "end_pos": 936 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": 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}, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YGK2-1", "uniprot_ac": "A0A8V0YGK2", "uniprot_id": "A0A8V0YGK2_CHICK", "mass": { "chemical_mass": 21891.0, "monoisotopic_mass": 21891.0 }, "refseq": {}, "gene_names": [ { "name": "CD164", "type": "recommended", "evidence": [ { "id": "A0A8V0YGK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGK2" } ] } ], "protein_names": [ { "name": "CD164 molecule", "type": "synonym", "evidence": [ { "id": "A0A8V0YGK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGK2/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGK2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGK2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CD164", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGK2", "locus": { "chromosome": "3", "start_pos": 66647828, "end_pos": 66636215, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010014156", "url": "https://www.ensembl.org/id/ENSGALG00010014156" } ] } } ], "crossref": [ { "id": "A0A8V0YGK2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YGK2", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR007947", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007947", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YGK2", "url": "https://www.orthodb.org/?gene=A0A8V0YGK2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11337", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11337", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11337:SF8", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11337:SF8", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05283", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05283", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YGK2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGK2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YGK2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGK2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGRRAALPLAALCFASALCGLAVGSGWEFALSNDATVDICGNISTCSSCIGNDTYETGCEWIRCNDSQMCINGTEATSEAYKSCTSEKQCSSATAVPFFNATTQPSNTTASPSNATTASSNTTSGSVTTAHATTAPNITNATTHAPASTTPITSAAKTTSTNATVTPAPSSRKSTFDAASFIGGIVLVLGLQAVIFFLYKFCRSKDRNYHTL", "length": 212, "header": "tr|A0A8V0YGK2-1|A0A8V0YGK2_CHICK Isoform 1 of CD164 molecule OS=Gallus gallus OX=9031 GN=CD164 PE=3 SV=1 CANONICAL=A0A8V0YGK2-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YGK2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGK2/entry#A0A8V0YGK2-1", "sequence": { "sequence": "MGRRAALPLAALCFASALCGLAVGSGWEFALSNDATVDICGNISTCSSCIGNDTYETGCEWIRCNDSQMCINGTEATSEAYKSCTSEKQCSSATAVPFFNATTQPSNTTASPSNATTASSNTTSGSVTTAHATTAPNITNATTHAPASTTPITSAAKTTSTNATVTPAPSSRKSTFDAASFIGGIVLVLGLQAVIFFLYKFCRSKDRNYHTL", "length": 212, "header": "tr|A0A8V0YGK2-1|A0A8V0YGK2_CHICK Isoform 1 of CD164 molecule OS=Gallus gallus OX=9031 GN=CD164 PE=3 SV=1 CANONICAL=A0A8V0YGK2-1" }, "locus": { "chromosome": "3", "start_pos": 66644939, "end_pos": 66636334, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034016.1", "url": "https://www.ensembl.org/id/ENSGALT00010034016.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019994.1", "url": "https://www.ensembl.org/id/ENSGALP00010019994.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": 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"evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGK2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGK2" } ], "pmid": "" }, { "name": "lysosome", "id": "GO:0005764", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005764", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGK2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGK2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 100, "end_pos": 102, "annotation": "n_glycosylation_sequon" }, { "start_pos": 107, "end_pos": 109, "annotation": "n_glycosylation_sequon" }, { "start_pos": 114, "end_pos": 116, "annotation": "n_glycosylation_sequon" }, { "start_pos": 121, "end_pos": 123, "annotation": "n_glycosylation_sequon" }, { "start_pos": 137, "end_pos": 139, "annotation": "n_glycosylation_sequon" }, { "start_pos": 140, "end_pos": 142, "annotation": "n_glycosylation_sequon" }, { "start_pos": 162, "end_pos": 164, "annotation": "n_glycosylation_sequon" }, { "start_pos": 42, "end_pos": 44, 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"https://www.ncbi.nlm.nih.gov/protein/XP_046768794" }, "gene_names": [ { "name": "COL10A1", "type": "recommended", "evidence": [ { "id": "A0A8V0YGK6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGK6" } ] }, { "name": "COL10A1", "type": "synonym", "evidence": [ { "id": "XP_046768794", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046768794" } ] } ], "protein_names": [ { "name": "Collagen type X alpha 1", "type": "synonym", "evidence": [ { "id": "A0A8V0YGK6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGK6/entry#names_and_taxonomy" } ] }, { "name": "collagen alpha-1(X) chain isoform X1", "type": "synonym", "evidence": [ { "id": "XP_046768794", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046768794" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052575.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_046768794", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046768794" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGK6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGK6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "COL10A1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGK6", "locus": { "chromosome": "3", "start_pos": 63709797, "end_pos": 63657722, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012719", "url": "https://www.ensembl.org/id/ENSGALG00010012719" } ] } } ], "crossref": [ { "id": "A0A8V0YGK6", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YGK6", "database": "AlphaFoldDB", "categories": [] }, { "id": "100858979", "url": "https://www.ncbi.nlm.nih.gov/gene/100858979", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001073", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001073", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008160", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008160", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008983", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008983", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050149", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050149", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050392", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050392", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050938", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050938", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IMFTYDE", "url": "https://omabrowser.org/oma/group/IMFTYDE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YA97", "url": "https://www.orthodb.org/?gene=A0A8V0YA97", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YGK6", "url": "https://www.orthodb.org/?gene=A0A8V0YGK6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YNG0", "url": "https://www.orthodb.org/?gene=A0A8V0YNG0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15427", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15427", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15427:SF48", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15427:SF48", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24023", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24023", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24023:SF880", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24023:SF880", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR37456", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR37456", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR37456:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR37456:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00386", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00386", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01391", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01391", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-1442490", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1442490", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-1650814", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1650814", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-2022090", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2022090", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-3000171", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3000171", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-8948216", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8948216", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_046768794", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046768794", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YA97", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YA97", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YA97-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YA97-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YGK6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGK6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YGK6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGK6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YNG0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNG0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YNG0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNG0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKKEDGFGNMHLQISLLLLFCLNIVHGSDGYFSERYQKQSSIKGPPHFLPFNVKSQGVQMRGEQGPPGPPGPIGPRGQPGPAGKPGFGSPGPQGPPGPPGPPGFSTVGKPGMPGLPGKPGERGLNGEKGEAGPVGLPGARGPQGPPGIPGPAGLSVPGKPGPQGPPGAQGPRGLPGEKGEPGVPGINGQKGEMGFGVPGRPGNRGLPGPQGPQGLPGPAGIGKPGENGLPGQPGMKGDRGLPGARGEAGIPGPQGPPGEPGEVGIGKPGPMGPPGPAGIPGAKGLPGPAGLPGSPGLPGFGKPGLPGMKGHRGPEGPPGFPGPKGDQGPAGVPGEPGPAGPQGNMGPQGLKGLPGENGLPGPKGDMGPVGPAGFPGAKGERGLPGLDGKPGYPGEQGLPGPKGHPGLPGQKGDTGHAGPPGLPGPVGPQGVKGVPGINGEPGPRGPSGIPGIRGPIGPPGMPGAPGAKGEAGAPGLPGPAGIATKGLRGPMGPPGPPGPKGNSGEPGLPGPPGPPGPPGQSTIPEGYVKGESRELSGMSFMKAGANQALTGMPVSAFTVILSKAYPGATVPIKFDKILYNRQQHYDPRTGIFTCRIPGLYYFSYHVHAKGTNVWVALYKNGSPVMYTYDEYQKGYLDQASGSAVIDLMENDQVWLQLPNSESNGLYSSEYVHSSFSGFLFAQI", "length": 683, "header": "tr|A0A8V0YGK6-1|A0A8V0YGK6_CHICK Isoform 1 of Collagen type X alpha 1 OS=Gallus gallus OX=9031 GN=COL10A1 PE=4 SV=1 CANONICAL=A0A8V0YGK6-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YA97-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGK6/entry#A0A8V0YA97-1", "sequence": { "sequence": "MHLQISLLLLFCLNIVHGSDGYFSERYQKQSSIKGPPHFLPFNVKSQGVQMRGEQGPPGPPGPIGPRGQPGPAGKPGFGSPGPQGPPGPPGPPGFSTVGKPGMPGLPGKPGERGLNGEKGEAGPVGLPGARGPQGPPGIPGPAGLSVPGKPGPQGPPGAQGPRGLPGEKGEPGVPGINGQKGEMGFGVPGRPGNRGLPGPQGPQGLPGPAGIGKPGENGLPGLPGARGEAGIPGPQGPPGEPGEVGIGKPGPMGPPGPAGIPGAKGLPGPAGLPGSPGLPGFGKPGLPGMKGHRGPEGPPGFPGPKGDQGPAGVPGEPGPAGPQGNMGPQGLKGLPGENGLPGPKGDMGPVGPAGFPGAKGERGLPGLDGKPGYPGEQGLPGPKGHPGLPGQKGDTGHAGPPGLPGPVGPQGVKGVPGINGEPGPRGPSGIPGIRGPIGPPGMPGAPGAKGEAGAPGLPGPAGIATKGLRGPMGPPGPPGPKGNSGEPGLPGPPGPPGPPGQSTIPEGYVKGESRELSGMSFMKAGANQALTGMPVSAFTVILSKAYPGATVPIKFDKILYNRQQHYDPRTGIFTCRIPGLYYFSYHVHAKGTNVWVALYKNGSPVMYTYDEYQKGYLDQASGSAVIDLMENDQVWLQLPNSESNGLYSSEYVHSSFSGFLFAQI", "length": 665, "header": "tr|A0A8V0YA97-1|A0A8V0YA97_CHICK Computationally mapped isoform of Collagen type X alpha 1 OS=Gallus gallus OX=9031 GN=COL10A1 PE=4 SV=1 CANONICAL=A0A8V0YGK6-1" }, "locus": { "chromosome": "3", "start_pos": 63709281, "end_pos": 63702592, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030439.1", "url": "https://www.ensembl.org/id/ENSGALT00010030439.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017654.1", "url": "https://www.ensembl.org/id/ENSGALP00010017654.1" } ] } }, { "isoform_ac": "A0A8V0YGK6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGK6/entry#A0A8V0YGK6-1", "sequence": { "sequence": "MKKEDGFGNMHLQISLLLLFCLNIVHGSDGYFSERYQKQSSIKGPPHFLPFNVKSQGVQMRGEQGPPGPPGPIGPRGQPGPAGKPGFGSPGPQGPPGPPGPPGFSTVGKPGMPGLPGKPGERGLNGEKGEAGPVGLPGARGPQGPPGIPGPAGLSVPGKPGPQGPPGAQGPRGLPGEKGEPGVPGINGQKGEMGFGVPGRPGNRGLPGPQGPQGLPGPAGIGKPGENGLPGQPGMKGDRGLPGARGEAGIPGPQGPPGEPGEVGIGKPGPMGPPGPAGIPGAKGLPGPAGLPGSPGLPGFGKPGLPGMKGHRGPEGPPGFPGPKGDQGPAGVPGEPGPAGPQGNMGPQGLKGLPGENGLPGPKGDMGPVGPAGFPGAKGERGLPGLDGKPGYPGEQGLPGPKGHPGLPGQKGDTGHAGPPGLPGPVGPQGVKGVPGINGEPGPRGPSGIPGIRGPIGPPGMPGAPGAKGEAGAPGLPGPAGIATKGLRGPMGPPGPPGPKGNSGEPGLPGPPGPPGPPGQSTIPEGYVKGESRELSGMSFMKAGANQALTGMPVSAFTVILSKAYPGATVPIKFDKILYNRQQHYDPRTGIFTCRIPGLYYFSYHVHAKGTNVWVALYKNGSPVMYTYDEYQKGYLDQASGSAVIDLMENDQVWLQLPNSESNGLYSSEYVHSSFSGFLFAQI", "length": 683, "header": "tr|A0A8V0YGK6-1|A0A8V0YGK6_CHICK Isoform 1 of Collagen type X alpha 1 OS=Gallus gallus OX=9031 GN=COL10A1 PE=4 SV=1 CANONICAL=A0A8V0YGK6-1" }, "locus": { "chromosome": "3", "start_pos": 63709281, "end_pos": 63657921, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030441.1", "url": "https://www.ensembl.org/id/ENSGALT00010030441.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017656.1", "url": "https://www.ensembl.org/id/ENSGALP00010017656.1" } ] } }, { "isoform_ac": "A0A8V0YNG0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGK6/entry#A0A8V0YNG0-1", "sequence": { "sequence": "MHLQISLLLLFCLNIVHGSDGYFSERYQKQSSIKGPPHFLPFNVKSQGVQMRGEQGPPGPPGPIGPRGQPGPAGKPGFGSPGPQGPPGPPGPPGFSTVGKPGMPGLPGKPGERGLNGEKGEAGPVGLPGARGPQGPPGIPGPAGLSVPGKPGPQGPPGAQGPRGLPGEKGEPGVPGINGQKGEMGFGVPGRPGNRGLPGPQGPQGLPGPAGIGKPGENGLPGQPGMKGDRGLPGARGEAGIPGPQGPPGEPGEVGIGKPGPMGPPGPAGIPGAKGLPGPAGLPGSPGLPGFGKPGLPGMKGHRGPEGPPGFPGPKGDQGPAGVPGEPGPAGPQGNMGPQGLKGLPGENGLPGPKGDMGPVGPAGFPGAKGERGLPGLDGKPGYPGEQGLPGPKGHPGLPGQKGDTGHAGPPGLPGPVGPQGVKGVPGINGEPGPRGPSGIPGIRGPIGPPGMPGAPGAKGEAGAPGLPGPAGIATKGLRGPMGPPGPPGPKGNSGEPGLPGPPGPPGPPGQSTIPEGYVKGESRELSGMSFMKAGANQALTGMPVSAFTVILSKAYPGATVPIKFDKILYNRQQHYDPRTGIFTCRIPGLYYFSYHVHAKGTNVWVALYKNGSPVMYTYDEYQKGYLDQASGSAVIDLMENDQVWLQLPNSESNGLYSSEYVHSSFSGFLFAQI", "length": 674, "header": "tr|A0A8V0YNG0-1|A0A8V0YNG0_CHICK Computationally mapped isoform of Collagen type X alpha 1 OS=Gallus gallus OX=9031 GN=COL10A1 PE=4 SV=1 CANONICAL=A0A8V0YGK6-1" }, "locus": { "chromosome": "3", "start_pos": 63709281, "end_pos": 63702592, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030440.1", "url": "https://www.ensembl.org/id/ENSGALT00010030440.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017655.1", "url": "https://www.ensembl.org/id/ENSGALP00010017655.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-1442490", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1442490", "resource": "Reactome", "description": "Collagen degradation" }, { "id": "R-GGA-1650814", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1650814", "resource": "Reactome", "description": "Collagen biosynthesis and modifying enzymes" }, { "id": "R-GGA-2022090", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2022090", "resource": "Reactome", "description": "Assembly of collagen fibrils and other multimeric structures" }, { "id": "R-GGA-3000171", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3000171", "resource": "Reactome", "description": "Non-integrin membrane-ECM interactions" }, { "id": "R-GGA-8948216", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8948216", "resource": "Reactome", "description": "Collagen chain trimerization" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2K7A5-1", "protein_name": "Collagen type X alpha 1 chain", "gene_name": "Col10a1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLPQIPFLLLVSLTLVHGTFYAERYQTPTGVKSALASPRTQYFIPYPIKGKEISVRGEQGIPGPPGPAGPRGHPGPSGPPGKPGYGSPGLQGEPGLPGPPGISATGKPGLPGKPGERGPHGHKGDIGPAGLPGPRGPPGPPGIPGPAGISVPGKPGQQGLTGAPGSRGFPGEKGAPGAPGVNGQKGETGYGTPGRPGERGLPGPQGPVGPPGSPGVGRRGENGFPGQPGIKGDRGFPGEAGPPGPPGPQGPPGKQGREGIGKPGATGSPGRPGIPGEKGHPGAPGIAGPPGAPGFGKQGLPGLRGQRGPAGLPGAPGAKGEQGPAGHPGEPGLTGSPGNMGPQGPKGIPGNHGIPGTKGETGLVGPAGPPGARGARGPPGLDGKTGYPGDPGLNGPKGNPGLPGPKGDPGVGGAPGLRGLVGPTGPKGVPGHNGEAGPRGEPGIPGTRGPIGPPGIPGFPGSKGDPGKPGAPGPAGIVTKGLNGPAGPPGRPGPRGHTGEPGLPGPPGPPGPPGPPSQAVIPDGFTKSGQRPRLSGMPLVSANQGVTGMPVSAFTVILSKAYPAVGAPIPFDEILYNRQQHYDPRSGIFTCKIPGIYYFSYHIHVKGTHVWVGLYKNGTPTMYTYDEYSKGYLDQASGSAIMELTENDQVWLQLPNAESNGLYSSEYVHSSFSGFLVAPI", "length": 680 }, "evidence": [ { "id": "A0A8V0YGK6", "url": "https://omabrowser.org/oma/group/A0A8V0YGK6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A3L7I4J1-1", "protein_name": "Collagen alpha-1(X) chain", "gene_name": "Col10a1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MLPPIAFLLLMSLTSVHGVFYAERYQTPTGIKGPLQNTKTQYFIPYSIKTKGIPVRGEQGVPGPPGPAGPRGHPGPSGPPGKPGYGSPGLQGEPGLPGPPGISATGKPGLPGLPGKPGERGPHGHKGDIGPAGLPGPRGPPGPPGIPGPAGISVSGKPGQQGLTGAPGPRGFPGEKGASGAPGVNGQKGETGYGAPGRPGERGLPGPQGPIGPPGPPGVGRRGENGFPGQPGIKGDRGFPGERGPSGPPGPQGPPGKQGREGIGKPGAAGTPGQPGIPGEKGHPGAPGIAGPPGAPGFGKPGLPGLRGQRGPAGLPGAPGAKGEQGPAGHPGEAGLTGSPGNMGPQGPKGIPGNHGVPGAKGEAGPIGPVGPPGARGARGPPGLDGKTGYPGEPGLNGPKGNPGLPGPKGDPGVGGAPGLQGPVGPTGAKGMPGHNGEAGPRGEPGKPGSRGPIGPPGTPGFPGAKGVPGNPGPPGPAGIATKGLSGPTGPPGPPGPRGHSGEPGLPGPPGPPGPPGQGVMPDGFIKAGQRPRLSGMPLVSANHGVTGMPVSAFTVVLSKAYPAVGTPIPFDEILYNRQQHYDPRTGIFTCKIPGIYYFSYHVHVKGTHVWVGLYKNGTPTMYTYDEYSKGYLDQASGSAIMELTENDQVWLQLPNAESNGLYSSQYVHSSFSGFLVAPM", "length": 680 }, "evidence": [ { "id": "A0A8V0YGK6", "url": "https://omabrowser.org/oma/group/A0A8V0YGK6/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "F1MZ30-1", "protein_name": "Collagen type X alpha 1 chain", "gene_name": "COL10A1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MLPQTALLLLMSLNLVHGVFYTERYQTPTGIKGPPSNTKTQFFIPYAIKGKGVSLRGEQGIPGPPGPAGPRGHPGPSGPPGKPGTGSPGPQGQPGLPGPPGPSATGKPGLPGLPGKQGERGLNGPKGDIGPAGLPGPRGPPGPPGIPGPAGISVPGKPGPQGPTGEPGPRGFPGEKGTSGVPGLNGQKGEMGHCTPCRPGERGLPGPQGPTGPPGPPGVGKRGENGLPGQPGLKGDQGVPGERGAAGPPGPQGPPGEQGPEGIGKPGAPGIPGQPGIPGMKGQPGAPGTAGLPGAPGFGKPGLPGLKGQRGPVGLPGSPGAKGEQGPAGHPGEAGLPGPSGNMGPQGPKGIPGNPGLPGPKGEMGPVGPAGNPGAKGERGSSGLDGKPGYPGEPGLNGPKGNPGLPGPKGDPGIAGSPGLPGPVGPAGAKGVPGHNGEAGPRGVPGIPGTRGPIGPPGIPGFPGSKGDVGTPGPPGPAGIAVKGLNGPTGPPGPPGPRGNAGEPGLPGPPGPPGPPGQAALPEDFVKAGQRPFVSANQGVTGMPVSAFTVILSKAYPAIGTPIPFDKILYNKQQHYDPRTGIFTCKIPGIYYFSYHIHVKGTHAWVGLYKNGTPVMYTYDEYIKGYLDQASGSAVIDLTENDQVWLQLPNAGSNGLYSSEYVHSSFSGFLVAPM", "length": 674 }, "evidence": [ { "id": "A0A8V0YGK6", "url": "https://omabrowser.org/oma/group/A0A8V0YGK6/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q03692-1", "protein_name": "Collagen alpha-1(X) chain", "gene_name": "COL10A1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLPQIPFLLLVSLNLVHGVFYAERYQMPTGIKGPLPNTKTQFFIPYTIKSKGIAVRGEQGTPGPPGPAGPRGHPGPSGPPGKPGYGSPGLQGEPGLPGPPGPSAVGKPGVPGLPGKPGERGPYGPKGDVGPAGLPGPRGPPGPPGIPGPAGISVPGKPGQQGPTGAPGPRGFPGEKGAPGVPGMNGQKGEMGYGAPGRPGERGLPGPQGPTGPSGPPGVGKRGENGVPGQPGIKGDRGFPGEMGPIGPPGPQGPPGERGPEGIGKPGAAGAPGQPGIPGTKGLPGAPGIAGPPGPPGFGKPGLPGLKGERGPAGLPGGPGAKGEQGPAGLPGKPGLTGPPGNMGPQGPKGIPGSHGLPGPKGETGPAGPAGYPGAKGERGSPGSDGKPGYPGKPGLDGPKGNPGLPGPKGDPGVGGPPGLPGPVGPAGAKGMPGHNGEAGPRGAPGIPGTRGPIGPPGIPGFPGSKGDPGSPGPPGPAGIATKGLNGPTGPPGPPGPRGHSGEPGLPGPPGPPGPPGQAVMPEGFIKAGQRPSLSGTPLVSANQGVTGMPVSAFTVILSKAYPAIGTPIPFDKILYNRQQHYDPRTGIFTCQIPGIYYFSYHVHVKGTHVWVGLYKNGTPVMYTYDEYTKGYLDQASGSAIIDLTENDQVWLQLPNAESNGLYSSEYVHSSFSGFLVAPM", "length": 680 }, "evidence": [ { "id": "A0A8V0YGK6", "url": "https://omabrowser.org/oma/group/A0A8V0YGK6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q05306-1", "protein_name": "Collagen alpha-1(X) chain", "gene_name": "Col10a1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLPQIPFLLLMFLTLVHGMFYAERYQTPTGIKGPLASPKTQYFIPYAIKSKGIPVRGEQGIPGPPGPTGPRGHPGPSGPPGKPGYGSPGLQGEPGLPGPPGISATGKPGLPGPPGKPGERGPYGHKGDIGPAGLPGPRGPPGPPGIPGPAGISVPGKPGQQGLTGAPGPRGFPGEKGAQGAPGVNGRKGETGYGSPGRPGERGLPGPQGPIGPPGPSGVGRRGENGFPGQPGIKGDRGFPGEMGPSGPPGPQGPPGKQGREGIGKPGAIGSPGQPGIPGEKGHPGAPGIAGPPGAPGFGKQGLPGLRGQRGPAGLPGAPGAKGERGPAGHPGEPGLPGSPGNMGPQGPKGIPGNHGIPGAKGEIGLVGPAGPPGARGARGPPGLDGKTGYPGEPGLNGPKGNPGLPGQKGDPGVGGTPGLRGPVGPVGAKGVPGHNGEAGPRGEPGIPGTRGPTGPPGVPGFPGSKGDPGNPGAPGPAGIATKGLNGPTGPPGPPGPRGHSGEPGLPGPPGPPGPPGQAVMPDGFIKAGQRPRLSGMPLVSANHGVTGMPVSAFTVILSKAYPAVGAPIPFDEILYNRQQHYDPRSGIFTCKIPGIYYFSYHVHVKGTHVWVGLYKNGTPTMYTYDEYSKGYLDQASGSAIMELTENDQVWLQLPNAESNGLYSSEYVHSSFSGFLVAPM", "length": 680 }, "evidence": [ { "id": "A0A8V0YGK6", "url": "https://omabrowser.org/oma/group/A0A8V0YGK6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9N178-1", "protein_name": "Collagen type X alpha 1 chain", "gene_name": "COL10A1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MLPQTALLLLLLSLNLVHGVFYTEQYQTPTGIKGPPSNTKAQFFIPYAIKSKGISLRGEQGIPGPPGPAGPRGHPGPSGPPGKPGFGSPGPQGQPGLPGPPGPSATGKPGLPGPQGKPGERGPYGPKGDMGPAGLPGPRGPPGPPGIPGPAGISVTGKPGQQGPAGAPGPRGFPGEKGAPGVPGINGQKGETGYGAPGRPGDRGLPGPQGPMGPPGPPGVGKRGENGFPGQPGIKGDRGFPGESGPAGPPGPQGPPGEQGREGIGKPGAPGAAGQPGLPGTKGHPGAPGMAGPPGAPGFGKPGLPGLKGQRGPIGLPGAPGAKGEQGPAGHPGEPGLTGPPGSRGPQGPKGIPGNNGVPGPKGEIGLAGPAGFPGAKGERGPSGLDGKPGYPGEPGLNGPKGNPGLPGPKGDPGIGGPPGLPGPVGPAGAKGVPGHNGEAGPRGAPGIPGTRGPIGPPGIPGFPGSKGDPGNPGPPGPAGIATKGLNGPTGPPGPPGPKGHAGEPGLPGPPGPPGPPGQAVPPEGFVKEGQRAFVSANQGVTGMPVSAFTVILSKAYPAIGAPIPFDKILYNGQQHYDPKTGIFTCRIPGIYYFSYHIHVKGTHAWVGLYKNGTPVMYTYDEYVKGYLDQASGSAILDLTDNDQVWLQLPNAGSNGLYSSEYVHSSFSGFLVAPM", "length": 675 }, "evidence": [ { "id": "A0A8V0YGK6", "url": "https://omabrowser.org/oma/group/A0A8V0YGK6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGK6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGK6" } ], "pmid": "" }, { "name": "cell cortex", "id": "GO:0005938", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005938", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGK6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGK6" } ], "pmid": "" }, { "name": "extracellular matrix", "id": "GO:0031012", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031012", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGK6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGK6" } ], "pmid": "" }, { "name": "collagen type X trimer", "id": "GO:0005599", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005599", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGK6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGK6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "extracellular matrix organization", "id": "GO:0030198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030198", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGK6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGK6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "extracellular matrix structural constituent conferring tensile strength", "id": "GO:0030020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGK6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGK6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 620, "end_pos": 622, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YGK6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGK6" }, { "id": "PS50871", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50871" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C1q", "eco_id": "ECO_0000259", "start_pos": 550, "end_pos": 683, "start_aa": "Thr", "end_aa": "Ile", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 620, "end_pos": 622 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YGL2-1", "uniprot_ac": "A0A8V0YGL2", "uniprot_id": "A0A8V0YGL2_CHICK", "mass": { "chemical_mass": 200417.0, "monoisotopic_mass": 200417.0 }, "refseq": { "ac": "NP_001182532", "name": "focadhesin", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001182532" }, "gene_names": [ { "name": "FOCAD", "type": "recommended", "evidence": [ { "id": "A0A8V0YGL2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGL2" } ] }, { "name": "FOCAD", "type": "synonym", "evidence": [ { "id": "NP_001182532", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001182532" } ] } ], "protein_names": [ { "name": "Focadhesin", "type": "synonym", "evidence": [ { "id": "A0A8V0YGL2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGL2/entry#names_and_taxonomy" } ] }, { "name": "focadhesin", "type": "synonym", "evidence": [ { "id": "NP_001182532", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001182532" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000093.1. On or before Dec 15, 2021 this sequence version replaced XP_015135573.2, NP_001182532.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001182532", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001182532" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGL2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGL2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "FOCAD", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGL2", "locus": { "chromosome": "Z", "start_pos": 34714281, "end_pos": 34614593, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010014153", "url": "https://www.ensembl.org/id/ENSGALG00010014153" } ] } } ], "crossref": [ { "id": "427233", "url": "https://www.ncbi.nlm.nih.gov/gene/427233", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR021392", "url": "https://www.ebi.ac.uk/interpro/entry/IPR021392", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR022542", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022542", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045163", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045163", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:427233", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427233", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "GQLFSWF", "url": "https://omabrowser.org/oma/group/GQLFSWF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YGL2", "url": "https://www.orthodb.org/?gene=A0A8V0YGL2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YMP6", "url": "https://www.orthodb.org/?gene=A0A8V0YMP6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YMY8", "url": "https://www.orthodb.org/?gene=A0A8V0YMY8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16212", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16212", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16212:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16212:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF11229", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11229", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12530", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12530", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001182532", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001182532", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YGL2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGL2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YGL2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGL2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YMP6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMP6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YMP6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMP6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YMY8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMY8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YMY8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMY8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSDDIKKRFEFPNTVIQSQAVGHLIAAVLKENASSEKITQTSHQTPALNLLWEKCCSENVALRTACSEGLVALVAENHAELSYVLHGAVNLIPSARNVHGLVKTIWKLLQIQAVQLGRNGDDAVLNLYGIRNNPHPLITVLENRPDCWPVLLQQITVFFHQCPERAQSSCVAIMAPFLRYLYCEPSQIREYAELRMGLLRILLQPRGPKHKEAPCVLEHHILQLLCDFIPHLQVKDLPQVTEALFFLQELFLSLLRFPAFWKVQLSQFCLQLICFCEVCLNVTGECSSLISLIEDNFELLKEVFPVEQCIIGLALLLLQTPESQQKSILSLAYKLFSSPENISATALVLVMPLLQILSSSSVGDCLQEDDSGTTRQQLATDLLEILKEEDVKNKKELMSCKLLFPITSSYCSLYTTWKILELMKEKSAVIDWLSSVRSLLPVTTQVPAHIFLLLAYLLIQEKGDSLRDVLQTTTEVAKADCSQVPSLIPVLVFILGRPLEPALYKDILYTLPSLGVHKVCVAQILRTIHMLGSTPKLRAITLRLMTSLWERQDRIYPELQKFLATSDVPSLVVDKDAQWEKVIAKAACIRDICKQRPYQHGADMLAAISQVLNECTKPDQASPAAIVLQGLQALCEAEVVCINSTWNALSPKLSCDTRPLILKALNELFALVPSLTVNTNEYEKFKAQVLSFLWKNTQNKEAIVAISAYKSLSSFGSDEHTILHLPEQARTEINSLEETDVNEDEEEKEVDLFVPGSSYIKLLSLTPDSVLGAFEEFATSLVKQEMTNMPRGVYHSALRGGATRTDQGKTVAGIPNFLLKMYERNKQPGMTPGLAAGMLLCYDLPVHMGRDGKPINRFLASRGRNFQQILVALIHEVNIQPSEWHRSILLPQSWLGFMSRTYGAVLQGRQAELEMQLKHGKEDPEDVQYKQFTAWLWVRDMLTDVIKGASKESPVVKGNSILALTGLAVAVSKYESNLSSDTEGMPETVPDFLPMQQWIYMVIETLFSIVNSRYRPKGQVFPWFYQKSYSGENTASAIARSCAATALSLLVPVIVVSCKEKVEEVLNMLTARLPGKPNADESQAVQIHMGLALGMFISRLCEEKVSELPGQQMNLVLMKSLDALEDCCFDSSLEYNTGCILGVGLVLSFLSHSSQTESRVHVSASLRKLCAYLDSSEDQSRWVQEVLAYSVACSCVSAFSVGIIEAAEAEEAMNKLRTLVEKNLQTSGFALALGTVVHGLSVCGHGKAEDLSNKLMPSWIKVVIAEGSPTMQRLAAVNGLVALVGSEGGMIQLKSESIQTSQFQSKLNEVIRTLTQIISFSGQIGLQTNAAGLLGHLHMSCLSSTQSRTSVPPDFSYLPESSFIRAAIDFVIESGKKGPESVPAQLVKVALAPIAVVGGSHQYPPVNWASVLSPLIRLNFGDEIKYLCLELAATQAQSSQNAAMLLGMWVAPPLVYSLSTKTQKYLFMSLSLWMKHVAEDKLQAFTEVFLVQQFEVNRIKNPEICQCVLQGLVQAMKIPNPAQYCWGFLCQATEKIFGLLPNKIQRSELEMYVSVAKCISEMADSEIDRIVQISKNNMEKAIFTKVYLISQGRLPLKNLSVVIETSTGYYQKESIVWMFLHSFYHSRIVSHENTGVMKRMDWLLDLMGYIGNLAYTSTPVQNVDLKEVIDFLLWLFAGSVVAWADHSAPLLLGLSAYWSPWKHQTVLPELSDDRVGKHSTDKLAMQETLTLLPSSISLLLAKEPWKEQTQKFIDWLISMLESPKEALSKSSTDLLKVTLLALRSLAEFKKKAVWTKAYGW", "length": 1800, "header": "tr|A0A8V0YGL2-1|A0A8V0YGL2_CHICK Isoform 1 of Focadhesin OS=Gallus gallus OX=9031 GN=FOCAD PE=1 SV=1 CANONICAL=A0A8V0YGL2-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YGL2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGL2/entry#A0A8V0YGL2-1", "sequence": { "sequence": "MSDDIKKRFEFPNTVIQSQAVGHLIAAVLKENASSEKITQTSHQTPALNLLWEKCCSENVALRTACSEGLVALVAENHAELSYVLHGAVNLIPSARNVHGLVKTIWKLLQIQAVQLGRNGDDAVLNLYGIRNNPHPLITVLENRPDCWPVLLQQITVFFHQCPERAQSSCVAIMAPFLRYLYCEPSQIREYAELRMGLLRILLQPRGPKHKEAPCVLEHHILQLLCDFIPHLQVKDLPQVTEALFFLQELFLSLLRFPAFWKVQLSQFCLQLICFCEVCLNVTGECSSLISLIEDNFELLKEVFPVEQCIIGLALLLLQTPESQQKSILSLAYKLFSSPENISATALVLVMPLLQILSSSSVGDCLQEDDSGTTRQQLATDLLEILKEEDVKNKKELMSCKLLFPITSSYCSLYTTWKILELMKEKSAVIDWLSSVRSLLPVTTQVPAHIFLLLAYLLIQEKGDSLRDVLQTTTEVAKADCSQVPSLIPVLVFILGRPLEPALYKDILYTLPSLGVHKVCVAQILRTIHMLGSTPKLRAITLRLMTSLWERQDRIYPELQKFLATSDVPSLVVDKDAQWEKVIAKAACIRDICKQRPYQHGADMLAAISQVLNECTKPDQASPAAIVLQGLQALCEAEVVCINSTWNALSPKLSCDTRPLILKALNELFALVPSLTVNTNEYEKFKAQVLSFLWKNTQNKEAIVAISAYKSLSSFGSDEHTILHLPEQARTEINSLEETDVNEDEEEKEVDLFVPGSSYIKLLSLTPDSVLGAFEEFATSLVKQEMTNMPRGVYHSALRGGATRTDQGKTVAGIPNFLLKMYERNKQPGMTPGLAAGMLLCYDLPVHMGRDGKPINRFLASRGRNFQQILVALIHEVNIQPSEWHRSILLPQSWLGFMSRTYGAVLQGRQAELEMQLKHGKEDPEDVQYKQFTAWLWVRDMLTDVIKGASKESPVVKGNSILALTGLAVAVSKYESNLSSDTEGMPETVPDFLPMQQWIYMVIETLFSIVNSRYRPKGQVFPWFYQKSYSGENTASAIARSCAATALSLLVPVIVVSCKEKVEEVLNMLTARLPGKPNADESQAVQIHMGLALGMFISRLCEEKVSELPGQQMNLVLMKSLDALEDCCFDSSLEYNTGCILGVGLVLSFLSHSSQTESRVHVSASLRKLCAYLDSSEDQSRWVQEVLAYSVACSCVSAFSVGIIEAAEAEEAMNKLRTLVEKNLQTSGFALALGTVVHGLSVCGHGKAEDLSNKLMPSWIKVVIAEGSPTMQRLAAVNGLVALVGSEGGMIQLKSESIQTSQFQSKLNEVIRTLTQIISFSGQIGLQTNAAGLLGHLHMSCLSSTQSRTSVPPDFSYLPESSFIRAAIDFVIESGKKGPESVPAQLVKVALAPIAVVGGSHQYPPVNWASVLSPLIRLNFGDEIKYLCLELAATQAQSSQNAAMLLGMWVAPPLVYSLSTKTQKYLFMSLSLWMKHVAEDKLQAFTEVFLVQQFEVNRIKNPEICQCVLQGLVQAMKIPNPAQYCWGFLCQATEKIFGLLPNKIQRSELEMYVSVAKCISEMADSEIDRIVQISKNNMEKAIFTKVYLISQGRLPLKNLSVVIETSTGYYQKESIVWMFLHSFYHSRIVSHENTGVMKRMDWLLDLMGYIGNLAYTSTPVQNVDLKEVIDFLLWLFAGSVVAWADHSAPLLLGLSAYWSPWKHQTVLPELSDDRVGKHSTDKLAMQETLTLLPSSISLLLAKEPWKEQTQKFIDWLISMLESPKEALSKSSTDLLKVTLLALRSLAEFKKKAVWTKAYGW", "length": 1800, "header": "tr|A0A8V0YGL2-1|A0A8V0YGL2_CHICK Isoform 1 of Focadhesin OS=Gallus gallus OX=9031 GN=FOCAD PE=1 SV=1 CANONICAL=A0A8V0YGL2-1" }, "locus": { "chromosome": "Z", "start_pos": 34713305, "end_pos": 34617897, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034033.1", "url": "https://www.ensembl.org/id/ENSGALT00010034033.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020004.1", "url": "https://www.ensembl.org/id/ENSGALP00010020004.1" } ] } }, { "isoform_ac": "A0A8V0YMP6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGL2/entry#A0A8V0YMP6-1", "sequence": { "sequence": "MNVHGLVKTIWKLLQIQAVQLGRNGDDAVLNLYGIRNNPHPLITVLENRPDCWPVLLQQITVFFHQCPERAQSSCVAIMAPFLRYLYCEPSQIREYAELRMGLLRILLQPRGPKHKEAPCVLEHHILQLLCDFIPHLQVKDLPQVTEALFFLQELFLSLLRFPAFWKVQLSQFCLQLICFCEVCLNVTGECSSLISLIEDNFELLKEVFPVEQCIIGLALLLLQTPESQQKSILSLAYKLFSSPENISATALVLVMPLLQILSSSSVGDCLQEDDSGTTRQQLATDLLEILKEEDVKNKKELMSCKLLFPITSSYCSLYTTWKILELMKEKSAVIDWLSSVRSLLPVTTQVPAHIFLLLAYLLIQEKGDSLRDVLQTTTEVAKADCSQVPSLIPVLVFILGRPLEPALYKDILYTLPSLGVHKVCVAQILRTIHMLGSTPKLRAITLRLMTSLWERQDRIYPELQKFLATSDVPSLVVDKDAQWEKVIAKAACIRDICKQRPYQHGADMLAAISQVLNECTKPDQASPAAIVLQGLQALCEAEVVCINSTWNALSPKLSCDTRPLILKALNELFALVPSLTVNTNEYEKFKAQVLSFLWKNTQNKEAIVAISAYKSLSSFGSDEHTILHLPEQARTEINSLEETDVNEDEEEKEVDLFVPGSSYIKLLSLTPDSVLGAFEEFATSLVKQEMTNMPRGVYHSALRGGATRTDQGKTVAGIPNFLLKMYERNKQPGMTPGLAAGMLLCYDLPVHMGRDGKPINRFLASRGRNFQQILVALIHEVNIQPSEWHRSILLPQSWLGFMSRTYGAVLQGRQAELEMQLKHGKEDPEDVQYKQFTAWLWVRDMLTDVIKGASKESPVVKGNSILALTGLAVAVSKYESNLSSDTEGMPETVPDFLPMQQWIYMVIETLFSIVNSRYRPKGQVFPWFYQKSYSGENTASAIARSCAATALSLLVPVIVVSCKEKVEEVLNMLTARLPGKPNADESQAVQIHMGLALGMFISRLCEEKVSELPGQQMNLVLMKSLDALEDCCFDSSLEYNTGCILGVGLVLSFLSHSSQTESRVHVSASLRKLCAYLDSSEDQSRWVQEVLAYSVACSCVSAFSVGIIEAAEAEEAMNKLRTLVEKNLQTSGFALALGTVVHGLSVCGHGKAEDLSNKLMPSWIKVVIAEGSPTMQRLAAVNGLVALVGSEGGMIQLKSESIQTSQFQSKLNEVIRTLTQIISFSGQIGLQTNAAGLLGHLHMSCLSSTQSRTSVPPDFSYLPESSFIRAAIDFVIESGKKGPESVPAQLVKVALAPIAVVGGSHQYPPVNWASVLSPLIRLNFGDEIKYLCLELAATQAQSSQNAAMLLGMWVAPPLVYSLSTKTQKYLFMSLSLWMKHVAEDKLQAFTEVFLVQQFEVNRIKNPEICQCVLQGLVQAMKIPNPAQYCWGFLCQATEKIFGLLPNKIQRSELEMYVSVAKCISEMADSEIDRIVQISKNNMEKAIFTKVYLISQGRLPLKNLSVVIETSTGYYQKESIVWMFLHSFYHSRIVSHENTGVMKRMDWLLDLMGYIGNLAYTSTPVQNVDLKEVIDFLLWLFAGSVVAWADHSAPLLLGLSAYWSPWKHQTVLPELSDDRVGKHSTDKLAMQETLTLLPSSISLLLAKEPWKEQTQKFIDWLISMLESPKEALSKSSTDLLKVTLLALRSLAEFKKKAVWTKAYGW", "length": 1705, "header": "tr|A0A8V0YMP6-1|A0A8V0YMP6_CHICK Computationally mapped isoform of Focadhesin OS=Gallus gallus OX=9031 GN=FOCAD PE=1 SV=1 CANONICAL=A0A8V0YGL2-1" }, "locus": { "chromosome": "Z", "start_pos": 34713305, "end_pos": 34624997, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034015.1", "url": "https://www.ensembl.org/id/ENSGALT00010034015.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019993.1", "url": "https://www.ensembl.org/id/ENSGALP00010019993.1" } ] } }, { "isoform_ac": "A0A8V0YMY8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGL2/entry#A0A8V0YMY8-1", "sequence": { "sequence": "MFETPALNLLWEKCCSENVALRTACSEGLVALVAENHAELSYVLHGAVNLIPSARNVHGLVKTIWKLLQIQAVQLGRNGDDAVLNLYGIRNNPHPLITVLENRPDCWPVLLQQITVFFHQCPERAQSSCVAIMAPFLRYLYCEPSQIREYAELRMGLLRILLQPRGPKHKEAPCVLEHHILQLLCDFIPHLQVKDLPQVTEALFFLQELFLSLLRFPAFWKVQLSQFCLQLICFCEVCLNVTGECSSLISLIEDNFELLKEVFPVEQCIIGLALLLLQTPESQQKSILSLAYKLFSSPENISATALVLVMPLLQILSSSSVGDCLQEDDSGTTRQQLATDLLEILKEEDVKNKKELMSCKLLFPITSSYCSLYTTWKILELMKEKSAVIDWLSSVRSLLPVTTQVPAHIFLLLAYLLIQEKGDSLRDVLQTTTEVAKADCSQVPSLIPVLVFILGRPLEPALYKDILYTLPSLGVHKVCVAQILRTIHMLGSTPKLRAITLRLMTSLWERQDRIYPELQKFLATSDVPSLVVDKDAQWEKVIAKAACIRDICKQRPYQHGADMLAAISQVLNECTKPDQASPAAIVLQGLQALCEAEVVCINSTWNALSPKLSCDTRPLILKALNELFALVPSLTVNTNEYEKFKAQVLSFLWKNTQNKEAIVAISAYKSLSSFGSDEHTILHLPEQARTEINSLEETDVNEDEEEKEVDLFVPGSSYIKLLSLTPDSVLGAFEEFATSLVKQEMTNMPRGVYHSALRGGATRTDQGKTVAGIPNFLLKMYERNKQPGMTPGLAAGMLLCYDLPVHMGRDGKPINRFLASRGRNFQQILVALIHEVNIQPSEWHRSILLPQSWLGFMSRTYGAVLQGRQAELEMQLKHGKEDPEDVQYKQFTAWLWVRDMLTDVIKGASKESPVVKGNSILALTGLAVAVSKYESNLSSDTEGMPETVPDFLPMQQWIYMVIETLFSIVNSRYRPKGQVFPWFYQKSYSGENTASAIARSCAATALSLLVPVIVVSCKEKVEEVLNMLTARLPGKPNADESQAVQIHMGLALGMFISRLCEEKVSELPGQQMNLVLMKSLDALEDCCFDSSLEYNTGCILGVGLVLSFLSHSSQTESRVHVSASLRKLCAYLDSSEDQSRWVQEVLAYSVACSCVSAFSVGIIEAAEAEEAMNKLRTLVEKNLQTSGFALALGTVVHGLSVCGHGKAEDLSNKLMPSWIKVVIAEGSPTMQRLAAVNGLVALVGSEGGMIQLKSESIQTSQFQSKLNEVIRTLTQIISFSGQIGLQTNAAGLLGHLHMSCLSSTQSRTSVPPDFSYLPESSFIRAAIDFVIESGKKGPESVPAQLVKVALAPIAVVGGSHQYPPVNWASVLSPLIRLNFGDEIKYLCLELAATQAQSSQNAAMLLGMWVAPPLVYSLSTKTQKYLFMSLSLWMKHVAEDKLQAFTEVFLVQQFEVNRIKNPEICQCVLQGLVQAMKIPNPAQYCWGFLCQATEKIFGLLPNKIQRSELEMYVSVAKCISEMADSEIDRIVQISKNNMEKAIFTKVYLISQGRLPLKNLSVVIETSTGYYQKESIVWMFLHSFYHSRIVSHENTGVMKRMDWLLDLMGYIGNLAYTSTPVQNVDLKEVIDFLLWLFAGSVVAWADHSAPLLLGLSAYWSPWKHQTVLPELSDDRVGKHSTDKLAMQETLTLLPSSISLLLAKEPWKEQTQKFIDWLISMLESPKEALSKSSTDLLKVTLLALRSLAEFKKKAVWTKAYGW", "length": 1759, "header": "tr|A0A8V0YMY8-1|A0A8V0YMY8_CHICK Computationally mapped isoform of Focadhesin OS=Gallus gallus OX=9031 GN=FOCAD PE=1 SV=1 CANONICAL=A0A8V0YGL2-1" }, "locus": { "chromosome": "Z", "start_pos": 34713305, "end_pos": 34622989, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034026.1", "url": "https://www.ensembl.org/id/ENSGALT00010034026.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020001.1", "url": "https://www.ensembl.org/id/ENSGALP00010020001.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:427233", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427233", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0AAA9TVP1-1", "protein_name": "Focadhesin", "gene_name": "FOCAD", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MLDDIRKRFEFPNSLIQSQAVGHLIAAVLKENSFSEKIHQCTNQTPALNLLWEKCCSDNVVVRTACCEGLVALVAQDHAEFSYVLNGILNLIPSTRNTHGLIKALMKLLQMQAVKEGHSGEKNIQDIYNIRNHPQPLITVLEHRPDCWPVILQQLTAFFQQCLERSEVSCIQIMAPFLWYLYCEPPQLQEYAKLRLTLLKVLLKPRVPCDKEQPSILEQQILQLCCDMVPCLQIKDLIQTTEVMLFIEEVYLNLLRYPVFWKIQLTQLTLQLLCVCEVSLNITGECSSLIHLLEHSVELLKEDFPVEPVIIGIALLLLQTPASQQKPILSLALKLLSSAESQKIPKSSLLLVMPLLQILSSTALEDCISVDEEGPSRQQLAVNLLEMVQQERYRDKHRKLSYKLAFPITSMYGSIFTAWRILEVMREESAASDWLASVESLLPITTVIPAHVFLLLAYLLVEDKGRNLHQILKVTTELAQADSSQVPNLIPVLMFKLGRPLAPVLYNDILYTLPTLGVHKVCIGQILRVIQLLGTTPQLKAVTLRLLTSLWEKQDRVYPELQRFMAMSDVPSLSVGKEVQWEKLIAKAASIRDICKQRPYQHGADMLAAISQVLNECTKPDQATPAALVLQGLHALCQAEVVCIRSTWNALSPKLSCDTRPLILKTLSELFSLVPSLTVNTAEYENFKVQVLSFLWNHTQNKDPIVANAAYKSLSHFGAGDHTILHLPEEVRPEIQTPDDLDEDEDEEGDEKEVDLSIPGSCYLKLLSLTAPSVLPALEEFFTSLVKQEMVNMPRGVYHSALKGGARLDQGKTVAGIPNFMLKMYETNKQPGLKPGLAGGMLFCYDISMYQSKDGKPLNRLMASRGRSFKQTSLALVHEVHIQPSEWHRAIFLPQAWLAYMTRAYHAILQGRIGELDLQLKHGKEGPEEVQYKKNTAWLWVRDMLTDEITKAAAKDSPVVKGNALLALSSLAVVVSKHEVSLCSDSDRVLEVQPHFLSVKDWVSMIFDTLLVIVDSHYQPRGHFFSSFYHKSYSGENTASAIARSAAATALSLLVPIFIISCKEKVEEILNMLTARLPGKPRADESQAVQIHMGLALGMFLSRLCEEKLSDISSQQMNLLLMKSLDALENCCFDPSLEYNTGCILGVGLVLSLMSHSGQTESRVHVAASLRKLSAYLDDSRSQSRTFQEVLAYTISCVCTSAFSAGIIEAVEAEDIMNKLRLLVDNSQQTSGFALALGNIIHGLSVCGHGKAEDLGNRLLPAWIKTVLTEGAPTMLCLAALHGMVALVGSEGDVMQLKSEAIQSSQSQGRLNEVIRTLTQVISVSGVIGLQSNAIWLLGHLHLSTLSSNQSRTSVPTDYSYLPENSFIRAAIGFFVTGGKKGPESVPPSLLKVVMKPIATVGENHQYPPVNWAALLSPLMRLNFGEEIQQLCLEIMVTQAQSSQNVTTLLGMWVMPPLIHGLSLNIKKYLLLSVPSWIKHVSDEQIVGFVESLMVAVFKAASPLSSPELRPSALQGLSQAMKLPSPSHHLWSLLSEATRKIFDLLPNKIRRNDLELYISVAKCLSEMTDDEADRVAQITESSLEKAAFVRLYLVSQGRFPLMGLTDVLSVAVQHREKDTLAWMTLHSLYQARIVSHANTGVLKRMEWLLELMGYIRNVAYQSTSVQNVALDEALDFLLLIFAAAVVAWADHAAPLLLGLSASWLPWHQENGPAGPASSLLGRSPLHRVTLQEAVTLLPSSMPLLLQKEPWKEQTQKFIDWLFSIMESPKEGLSAKSKDLLKATLLSLRVLPEFKKKAVWTRAYGW", "length": 1805 }, "evidence": [ { "id": "A0A8V0YGL2", "url": "https://omabrowser.org/oma/group/A0A8V0YGL2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A2AKG8-1", "protein_name": "Focadhesin", "gene_name": "Focad", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSDDIKKRFDFPNSLIQSQAVGHLIAAVLKEHGVSEKIHQSTNQTAALNLLWEKCCSDHVVVRTACSEGLVALVAQGHAEFSYVLNGILNLTPSARNMSGLIKALMKLLQMQALREGQSGEKDIQDIYSIRNPPQPLITVLEHRPDCWPLLLQQLTAFFQQCPERSEASCVQIMAPFLWYLYCEPSQLEEYAKLRLSLLKVLLQPRGVCEEAQLSVREQSTLQLCCSMLPCLQMKDLMQTTEMMLFVEEVYLSLLRHPGFWKSQLTQLTLQLLCICEVSLKITGECSSLIHLLERSVELLGEDFPVELVIIGIALLLLQMPASQQKPLLNLALKLLSLTEGQKIPKASLLLLVPLLQILSSTALEDCLAMGEEGPSRQQLALSLVEVLQKERHGDDSHTISCRLAFPVSSMYGSIFTAWRILDVIGEESATSDWLATVESLLSATTVIPPHVFLLLAYLLVEDVGQNLQQILRVTTQLAQADSSQVPNLIPVLMFKLGRPLDPVSYNHILYTLPTLGVHKVCVGQILRVIQLLGTTPRLRAVTLRLLTSLWEKQDRVYPELQRFMAVSDAPSLSVGKELQWEKLIAKAASIRDICKQRPYQHGADMLAAISQVLNECTKPDQATPAALVLQGLHALCQAEVVCIRSTWNALSPKLSCDMRPLILKTLSELFSLVPSLTVNTVEYENFKVQVLSFLWTHTQNKNPTVASAAYKSLSHFSAGEHTILHLPEKIRPEMPVPGELDEEESVDLSIPGACFLRLLTITAPSVLPALEEFFTSLVRQEMVNMPRGIYHSALKGGVRSDQGKTVAGIPNFILKTYETNKQPGLKPGLAGGMLFCYDLAMYQSKDGKPLNRLMASRGRSFKQTTLALIHEVHVQLSEWHRAIFLPQAWLAYMTRAYHAILQGRIAELELQLQHGKEGPEEVQYKRSTAWLWVRDMLTDEITKTAAKESPVVKANALLALSSLAVVVSKHEASLCSDSDGVLEIQPNFLPVKEWVSMVLNTLLVIVDSHYHPSGQLFTCFYHKSYSGENTASAIARSAAATALSLLVPVFIISCKEKVEEILNMLTARLPGKPSADESQAVQIHMGLALGMFLSRLCEEKLSDMSGQQMNLLLMKSLDALESCCFDPSLEYNTGCILGVGLALSLMSHSSHTESRVHVAASLRKLSTYLDESGSQSRTFQEVLVYTLSCVCTSAFSAGIIEAAEAEDIMSKLQLLVENNQQTSGFALALGNLVYGLSVCGHGKAEDLGNRLRPSWIKVVLTEGAPTMLCLAALHGLVALVGSDVDVMQLKSEAIQNTHFQARLNEVIRTLTEVISVSGVIGLQSNAIWLLGHLHLSTLSSNQSRTSVPTDYSYLPEGSFIRAAIGFFITGGKKGPEAVPPSLLKVVMKPIATVGESYQYPPANLAALLSPLMRLNFGEEIQQLCLEIAVTQAPSSQSAASLLGLWVMPPLIHGLSLNIKKYLLVSMPLWAKHVSDEQIQGFVENLMVEVFKTASQPCHPEMCLSALQGLSQAMKLPSPSHHLWSLLCDATGRIFDLLPNRIRRNDLELYISIAKCLSEMTDEGVNQVSQITKDNIEKAAFVKLYLVSQGRLPLMSLTDLLTAAMQHPEKETLAWMILHSLYQARIVNHANTGVLKRLEWLLELMGYVRNIAYQSAPIQNVAPEEALDFLMLIFAAAVVAWADHEAPLLLGLSASWLPWHQQNGPGGPAAALLGRSPMHRVTVQEVLTQLPRSMLLLLQKEPWKEQTQKFIDWLLSIMEIPNKAFAAKSKDLLKATLLSLRVLPEFKKKAVWTRAYGW", "length": 1798 }, "evidence": [ { "id": "A0A8V0YGL2", "url": "https://omabrowser.org/oma/group/A0A8V0YGL2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E7FGT5-1", "protein_name": "Focadhesin", "gene_name": "focad", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTETLKARLEFPNSLIQAQAVRTLVAAVLKEKGQNEKICQTSTKGPALESLWEQCSSDSTVVRSACCNALVLLVEQGHADLPYVLNTTLNLLPSARNVQGLIKVVGRLLQIQAGQRENRASFTCPYSIRSFPHPYITVLENRPDCWPALLQEIDDFLQLATDKDEPVFVEMLVPFLRYLYCEPQRLSENALLRQSLLRVLLQPREAPESDRLEEKGASSTRVVRELIRSLFDLLPHMLVDSVTAVVELSSFAESLTAALISHPELWRKELTRLALQLLCACQLTIHLGGELMSLLHTLHHIIPAHAEELPAEQVIMGISLLLLNASVSQQTALLDLAVKIVPPELPPPWGASLLVMPLLHVLSCSSLMEALTDTQTHTKNQKLANSLLQTVQREPARRKEDSMQLDLPLSTWYSELQVAVSVLHRVSTDSTSSSEWLYSLQSSLSVCENVPDTVCLLVSHLIFRSDGDLCRLALETAAAIAEADPAKVPCLLPVLMFKLSRVSDPALSLSVLYTLPKLGTHKLCIPQVLHVLQTVGSSSRLRPVALRLLALLWKKQDRVYPDLQRLMCQLDKSSVVMGKDTQWEQILARAACVRDICRERPYQHGGDMLAAIRDTLLQFSRKDQATPVALALQALQELCRAEVVDICSTWKALSPKLLSDTRPLVLKATAELLALVPDLNVKTEEYEKFGSEAVGVLWGYALSQDSVVASQGFKALSEYPESSHTILHLPEQARPIPKQPEVEDEVKQNEEENEEEEDISVPGASYVKLVSLTSLSVLPALETFLTALVRQEMKQMPRGVYHSALTGGNLRSDQGKTVSGIPSFMLKMYEKNKQPGLKPGLAAGLLLCYDLPVQTDKDGRPIIRFLVSRGRSYQQMLATFIHEVNIQPSEWHRSLLLPQAWRGFMSRAFHALLQGRKAELEMLQKQGKESPEELQYQQHYAWLWVRDRLTDVVKSAAKDSPVVQGNSILALSGLAVVLTRYESNLPAQSESGPEAGPDIFPTVHWLSMVIDTLLSIVSSNSNPKAQVFPWFVHRSYSGENTASVIARSCAALGLALLVPVLVTWRRDSIPSILGTLEAGLPGSATADESQALQFHSGLALGMFLAWLLDERVSDISGQSVAELLMKHLKRLEVCCFDPNLEYNAGCVLGVGLVLSSLSSSSQCERDRVHVSHTLDRLLQSLQDSSNNSRMMQEVVAYSVACVGVSAFSAGIIEASKAEESMNTLRALTEESQQTPGFALALGQTVFGLSSFGHGKAVDIQPRLLAAWTKILLAEGCPTMQRLSALNGLIALVGSETALIQMKSECEETSLQHSRLNEVIRAITQIITFSGTIGLQSNGACLLGHLHLTHASSRHSRTAVPQDFGYLSESSVIRASVDFITEAGRKGPEFTAPQRVKTLLSALAAVGADFQYPPVNWSSVLSPLMRLGFGEEVQHYCLELAASQTQSSQSASLFLGVWLVPPLVHSLSLRTRAHLYESLSCWMKHVAEDKLQVYVDSLAVQQFEPLTRLQRLSLCLSILHGLSRAMTAPNPPQNCWSVLCSTAEKIYNLLPDSIPAAEVALYEAMCSCLSEMSDAEIDRIVKVSEANVEKTAFILSYLVSKGRVPLLGLNDVISTILQVGSKRPISWLLLQGLHQSRFASGPNTGVSKRMEWLLELMGHIRNVAYGSPSVKCVDVLQGTDFLLGVFAAAVVSWADHGGPLLVGIRARWFPWPQSAELCHGLYANPEDTELPVASCLLAIPYSIRKLLDKEPWKSQSQKFIDWLFSITEAPKQAFSETAVLTAKAALMALRSSSEFKKKTVWTRAYGW", "length": 1806 }, "evidence": [ { "id": "A0A8V0YGL2", "url": "https://omabrowser.org/oma/group/A0A8V0YGL2/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1LU27-1", "protein_name": "Focadhesin", "gene_name": "Focad", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSDDIKKRFDFPNSLIQSQAVGHLIAAVLKEHGASEKIHQSTNQTAALNLLWEKSCSDNVVVRTACSEGLVALVAQGHAEFSYVLNGILNLIPSARNMSGLIKALMKLLQMQASREGQGGAKDLQDLYSIRNPPQPLITVLEHRPDCWPLLLQQLTAFFQQCPERSEASCVQIMAPFLWYLYCEPSQLQEYAKLRLSLLKVLLQPRGVCEEAQPSVLEQQILQLCCNMVPCLQMKDLMQTTEMTLFVEEVYLSLLRHPAFWKRQLTQLTVQLLCICEVSLKTTGECSSLIQLLERSVELLGEDFPVKLVIIGIALILLQTPASQQKPVLNLTLKLLSLTEGQRIPKASLLLLVPLLQILSSTALEDCLATGEEGPSRQQLALSLLEVLQRECHGDDRHTISCRLAFPVSSMYGSVFTACRILEVMGEASAASDWLAAVESLLPATTVIPPHVFLLLAHLLVEDGGQNLQQILKVTTQLAQADSSQVPHLIPVLMFKLGRPLDPVSYNHILYTLPTLGVHKVCVGQILRVIQLLGTTPRLRAVTLRLLTSLWEKQDRVYPELQRFMAMSDAPSLSVGKELQWEKLIAKAASIRDICKQRPYQHGADMLAAISQVLNECTKPDQASPAALVLQGLHALCQAEVVCIRSTWNALSPKLSCDMRPLILKTLSELFSLVPSLTVNTVEYENFKVQVLTFLWTHTQNKDPIVASAAYKSLSHFSAGEHTILHLPEKIRPEMPVPDELDEEESVDLSIPGSCYLRLLTITAPSILPALEEFFTSLVRQEMVNMPRGIYHSALKGGVCSDQGKTVAGIPNFILKTYETNKQPGLKPGLAGGMLFCYDVAMYQSKDGKPLNRLMASRGRTFKQTTLALVHEVHVQLSEWHRAIFLPQAWLAYMTRAYHAILQGRIAELELQLQHGKEGPEEVQYKRSTAWLWVRDMLTDEITKTAAKESPVVKGNALLALSSLAVVVSKHEASLSSESDGVLEVQPNFLPVKEWVSMVLNTVLVIVDSHYHPRGQLFTCFYHKSYSGENTASAIARSAAATALSLLVPVFIISCKEKVEEILNMLTARLPGKPSADESQAVQIHMGLALGMFLSRLCEEKLSDMSGQQMSLLLMKSLDALESCCFDPSLEHNTGCILGVGLALSLMSHSSHTESRVHVAASLRKLSAYLDESGSQSRTFQEVLAYTLSCVCTSAFSAGIIEAVEAEETMTKLQLLVENNQQTSGFALALGNLVYGLSVCGHGKAEDLGNRLRPSWIKIVLSEGAPTMLCLAALHGLVALVGSDVDVMQFQSEAIHNSQFQARLNEVIRTLTEVISVSGVIGLQSNAIWLLGHLHLSTLSSNQSRTSVPTDYSYLPEGSFIRAAIGFFITGGKKGPEAVPPSLLKVVMKPIATVGENYQYPPANLAALLSPLMRLNFGEEIQQLCLEIAVSQAPSSQSAAALLGLWVMPPLVHGLSLNIKKYLLVSMPLWAKHVSDEQIQGFVENLMVAVFKPASQPCHPEMCPSALQGLSQAMKLPSPSHHLWSLLCDATGRIFDLLPNRIRRNDLELYISIAKCLSEMTDEGANQVSQITKENIEKAAFVKLYLISQGRLPLMSLTDLLTAAMQHPSKETLAWMILHSLYQARIVNHTNTGVLKRLEWLLELMGYMRNIAYQSASAQNVPPAEALDFLMLIFAAAVVAWADHEAPLLLGLSASWLPWHQENGPGGPAAALLGRSPMHRVTVQEVLTLLPTSMLLLLQKEPWKEQTQKFIDWLFSIMEIPNEAFAATSKDLLKATLLSLRVLPEFKKKAVWTRAYGW", "length": 1798 }, "evidence": [ { "id": "A0A8V0YGL2", "url": "https://omabrowser.org/oma/group/A0A8V0YGL2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5VW36-1", "protein_name": "Focadhesin", "gene_name": "FOCAD", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSDDIRKRFEFPNSLIQSQAVGHLIAAVLKENGFSEKIHQSTNQTPALNLLWEKCCSDNVVVRTACCEGLVALVAQDHAEFSYVLNGILNLIPSTRNTHGLIKAIMHLLQMQALKEGQGGEKNIQSIYTIRNHPHPLITVLEHRPDCWPVFLQQLTAFFQQCPERLEVSCIQIMAPFLWYLYCEPSQLQEYAKLRLALLKVLLQPQVLCDKDQPSILEQQILQLCCDIVPCLQVKDLIQTTEAMMFIEEVCLSLLRHPVFWKIQLTQMSLQLLCVSEVSLKITGECSSSIHLLEHSVELLKEDFPVELVIIGIALLLLQTPASQQKPILNLALKLLSVTEDQKIPKSSLLLVMPILQILSSTALEDCISVDEEGPSRQQLALNLLEMIQQECYRDDHQKLSYKLVCPVTSMYGTIFTAWRILEVMTDSSAASDWLASVESLLPITAVIPAPAFLLLAHLLVEDKGQNLHQILKVTTELAQADSSQVPNLIPVLMFKLGRPLEPILYNDILYTLPKLGVHKVCIGQILRIIQLLGTTPRLRAVTLRLLTSLWEKQDRVYPELQRFMAVSDVPSLSVGKEVQWEKLIAKAASIRDICKQRPYQHGADMLAAISQVLNECTKPDQATPAALVLQGLHALCQAEVVCIRSTWNALSPKLSCDTRPLILKTLSELFSLVPSLTVNTTEYENFKVQVLSFLWTHTQNKDPIVANAAYRSLANFSAGEHTILHLPEKIRPEIPIPEELDDDEDVEDVDLSVPGSCYLKLLSLTPPLVLPALEEFFTSLVKQEMVNMPRGIYHSALKGGARSDQGKTVAGIPNFILKMYETNKQPGLKPGLAGGMLFCYDVSMYQSKDGKPLNRLMASRGRSFKQTSLALVHEVHIQLSEWHRAIFLPQAWLAYMNRAYHAILQGRLGELELQLKHGKEEPEEVQYKKSTAWLWVRDMLTDEITKAAAKESPVVKGNALLALSSLAVVVSRHEASLSSDSDGLLEVQPNFLSMKEWVSMVLDTLLVIVDSHYQPRGQLLSWFYYKSYSGENTASAIARSAAATALSLLVPVFIISCKEKVEEILNMLTARLPGKPSADESQAVQIHMGLALGMFLSRLCEEKLSDISGQEMNLLLMKSLDALENCCFDTSLEYNTGCILGVGLVLSLMSHSSQMQSRVHVAALLRKLSAHVDDSGSQSRTFQEVLAYTLSCVCTSAFSAGIIEATEAEDVMNKLRLLVENSQQTSGFALALGNIVHGLSVCGHGKAEDLGSKLLPAWIRIVLTEGTPTMLCLAALHGMVALVGSEGDVMQLKSEAIQTSHFQGRLNEVIRTLTQVISVSGVIGLQSNAVWLLGHLHLSTLSSSQSRASVPTDYSYLPESSFIGAAIGFFITGGKKGPESVPPSLLKVVMKPIATVGESYQYPPVNWAALLSPLMRLNFGEEIQQLCLEIMVTQAQSSQNAAALLGLWVTPPLIHSLSLNTKRYLLISAPLWIKHISDEQILGFVENLMVAVFKAASPLGSPELCPSALHGLSQAMKLPSPAHHLWSLLSEATGKIFDLLPNKIRRKDLELYISIAKCLLEMTDDDANRIAQVTKSNIEKAAFVKLYLVSQGRFPLVNLTDMLSVAVQHREKEVLAWMILHSLYQARIVSHANTGVLKRMEWLLELMGYIRNVAYQSTSFHNTALDKALDFFLLIFATAVVAWADHTAPLLLGLSASWLPWHQENGPAGPVPSFLGRSPMHRVTLQEVLTLLPNSMALLLQKEPWKEQTQKFIDWLFSIMESPKEALSAQSRDLLKATLLSLRVLPEFKKKAVWTRAYGW", "length": 1801 }, "evidence": [ { "id": "A0A8V0YGL2", "url": "https://omabrowser.org/oma/group/A0A8V0YGL2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGL2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGL2" } ], "pmid": "" }, { "name": "focal adhesion", "id": "GO:0005925", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005925", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGL2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGL2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "regulation of post-transcriptional gene silencing", "id": "GO:0060147", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060147", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGL2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGL2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1598, "end_pos": 1600, "annotation": "n_glycosylation_sequon" }, { "start_pos": 281, "end_pos": 283, "annotation": "n_glycosylation_sequon" }, { "start_pos": 32, "end_pos": 34, "annotation": "n_glycosylation_sequon" }, { "start_pos": 341, "end_pos": 343, "annotation": "n_glycosylation_sequon" }, { "start_pos": 643, "end_pos": 645, "annotation": "n_glycosylation_sequon" }, { "start_pos": 977, "end_pos": 979, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YGL2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGL2" }, { "id": "PF12530", "database": "Pfam", "url": 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This record is derived from a genomic sequence (NC_052535.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015134118.1. 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} ], "sequence": { "sequence": "MDEENENAAIEKVAHTIVKKVIRAAQEYYLNNVQKEEEAEYTARNIQWTTCESFTVERGLQQIEEYISQTWELHKSWLHCSEFLWEEDLQNSKKYHYRVLWSIPTRRKPIPLATASTYFVIEISKIKPVTLPVEVFFFLESSRLIHRPEQCRFREKWLKDIIENKIILRERLKLP", "length": 175, "header": "tr|A0A8V0YGM4-1|A0A8V0YGM4_CHICK Isoform 1 of A-kinase anchoring protein 14 OS=Gallus gallus OX=9031 GN=AKAP14 PE=4 SV=1 CANONICAL=A0A8V0YGM4-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YGM4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGM4/entry#A0A8V0YGM4-1", "sequence": { "sequence": "MDEENENAAIEKVAHTIVKKVIRAAQEYYLNNVQKEEEAEYTARNIQWTTCESFTVERGLQQIEEYISQTWELHKSWLHCSEFLWEEDLQNSKKYHYRVLWSIPTRRKPIPLATASTYFVIEISKIKPVTLPVEVFFFLESSRLIHRPEQCRFREKWLKDIIENKIILRERLKLP", "length": 175, "header": "tr|A0A8V0YGM4-1|A0A8V0YGM4_CHICK Isoform 1 of A-kinase anchoring protein 14 OS=Gallus gallus OX=9031 GN=AKAP14 PE=4 SV=1 CANONICAL=A0A8V0YGM4-1" }, "locus": { "chromosome": "4", "start_pos": 16448120, "end_pos": 16446300, "strand": "+", "evidence": [ { "database": 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"sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YGN5-1", "uniprot_ac": "A0A8V0YGN5", "uniprot_id": "A0A8V0YGN5_CHICK", "mass": { "chemical_mass": 24753.0, "monoisotopic_mass": 24753.0 }, "refseq": { "ac": "XP_040512123", "name": "spindle and kinetochore-associated protein 1-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040512123" }, "gene_names": [ { "name": "LOC121108481", "type": "recommended", "evidence": [ { "id": "A0A8V0YGN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGN5" } ] }, { "name": "LOC121108481", "type": "synonym", "evidence": [ { "id": "XP_040512123", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040512123" } ] } ], "protein_names": [ { "name": "SKA complex subunit 1", "type": "recommended", "evidence": [ { "id": "A0A8V0YGN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGN5/entry#names_and_taxonomy" } ] }, { "name": "Spindle and kinetochore-associated 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This record is derived from a genomic sequence (NC_052572.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040512123", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040512123" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGN5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGN5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LOC121108481", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGN5", "locus": {} } ], "crossref": [ { "id": "A0A8V0YGN5", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YGN5", "database": "AlphaFoldDB", "categories": [] }, { "id": "121108481", "url": "https://www.ncbi.nlm.nih.gov/gene/121108481", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR009829", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009829", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042031", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042031", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "XYMKSRL", "url": "https://omabrowser.org/oma/group/XYMKSRL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YGN5", "url": "https://www.orthodb.org/?gene=A0A8V0YGN5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR28573", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28573", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR28573:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28573:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07160", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07160", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_040512123", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040512123", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YGN5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGN5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YGN5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGN5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEAEGLEALSRHLAAKIGLIKRLLQLRGLGRREMLAEVGMEVAVLHGLLGRMEEEVNQRRQLAAALQEMRKRAEKEKWEAERLQLVKKAAKEAPLVNDAPLISDEEFESVPGYMRGRLTLAQTNAALRALHAAAASKYRLLRHPPKSLPASSRALCHRFREEETKETQGLTFVVEADLKEFTQLKVDRTFHRIVGVLRHCRRLREVRGARLVRYVLP", "length": 217, "header": "tr|A0A8V0YGN5-1|A0A8V0YGN5_CHICK Isoform 1 of SKA complex subunit 1 OS=Gallus gallus OX=9031 GN=LOC121108481 PE=3 SV=1 CANONICAL=A0A8V0YGN5-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YGN5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGN5/entry#A0A8V0YGN5-1", "sequence": { "sequence": "MEAEGLEALSRHLAAKIGLIKRLLQLRGLGRREMLAEVGMEVAVLHGLLGRMEEEVNQRRQLAAALQEMRKRAEKEKWEAERLQLVKKAAKEAPLVNDAPLISDEEFESVPGYMRGRLTLAQTNAALRALHAAAASKYRLLRHPPKSLPASSRALCHRFREEETKETQGLTFVVEADLKEFTQLKVDRTFHRIVGVLRHCRRLREVRGARLVRYVLP", "length": 217, "header": "tr|A0A8V0YGN5-1|A0A8V0YGN5_CHICK Isoform 1 of SKA complex subunit 1 OS=Gallus gallus OX=9031 GN=LOC121108481 PE=3 SV=1 CANONICAL=A0A8V0YGN5-1" }, "locus": { "chromosome": "Z", "start_pos": 49676, "end_pos": 45070, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026599.1", "url": "https://www.ensembl.org/id/ENSGALT00010026599.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015162.1", "url": "https://www.ensembl.org/id/ENSGALP00010015162.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "regulation of microtubule polymerization or depolymerization", "id": "GO:0031110", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031110", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGN5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGN5" } ], "pmid": "" }, { "name": "mitotic cell cycle", "id": "GO:0000278", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000278", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGN5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGN5" } ], "pmid": "" }, { "name": "chromosome segregation", "id": "GO:0007059", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007059", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGN5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGN5" } ], "pmid": "" }, { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGN5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGN5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "microtubule binding", "id": "GO:0008017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008017", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGN5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGN5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "spindle microtubule", "id": "GO:0005876", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005876", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGN5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGN5" } ], "pmid": "" }, { "name": "mitotic spindle", "id": "GO:0072686", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072686", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGN5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGN5" } ], "pmid": "" }, { "name": "outer kinetochore", "id": "GO:0000940", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000940", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGN5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGN5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YGP2-1", "uniprot_ac": "A0A8V0YGP2", "uniprot_id": "A0A8V0YGP2_CHICK", "mass": { "chemical_mass": 74958.0, "monoisotopic_mass": 74958.0 }, "refseq": {}, "gene_names": [ { "name": "ATF6B", "type": "recommended", "evidence": [ { "id": "A0A8V0YGP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGP2" } ] } ], "protein_names": [ { "name": "Activating transcription factor 6 beta", "type": "synonym", "evidence": [ { "id": "A0A8V0YGP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGP2/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGP2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGP2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ATF6B", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGP2", "locus": {} } ], "crossref": [ { "id": "A0A8V0YGP2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YGP2", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd14700", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14700", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "424365", "url": "https://www.ncbi.nlm.nih.gov/gene/424365", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004827", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004827", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046347", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046347", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051882", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051882", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "WSINNQF", "url": "https://omabrowser.org/oma/group/WSINNQF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YGP2", "url": "https://www.orthodb.org/?gene=A0A8V0YGP2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YJM8", "url": "https://www.orthodb.org/?gene=A0A8V0YJM8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YPH3", "url": "https://www.orthodb.org/?gene=A0A8V0YPH3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46164", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46164", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46164:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46164:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00170", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00170", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-381033", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-381033", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9909505", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9909505", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YGP2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGP2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YGP2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGP2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJM8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJM8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJM8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJM8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YPH3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPH3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YPH3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPH3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAAKAEWEPAGLLPAAGGGLDWETVLGEELGELLGAAESRRASRDEPDSFQENDLYNFHFDLDLMSWDSDLWNITSHSYSDANVKTEPLSPAPSTCSVPSPSSVDSPVQNVPDDMDFSCSSQMSPISLYCKSSRSPASPEGDAEKKPIVGVTSRSANNSVKTLKRCGQTASRPSIQPKPLLPAVPEAQANIGIPAKTIIIQTLPTLVPLPKHQPVVNIQPAPPKGPSVVLPQPAVVQLQASGVLPASQPVIAVTGGTTQLHNHTVGALPPTAGNGSANGKITVAKPLLQSTTPAVGLDLNVLRRQQRMIKNRESAFQSRKKKKEYMLGLEARLEAALLENEKLKKENSTLKRQLDEVVLENQKLKVSSPKRRTLCVMVILAFIMLNYGPLSVFEKDPNGVDSAVSSNHRTRNLLEFSASKEPSPAQKIPIDIISEKINRYDNSVSDNKALMIVSEEPLLYISPPPPPCQPLINRTESQRLNHELRGWVHRHEVERTRSRRKSNNQHQKARVMQSSVSQKVHSQLMTMPYTDTSLRNSGNELQVYYASPRSYQDFFEAIHRKEDTFYVVSFRRDHLLLPATTHNKTRRPKMSIVLPAVNINENVINGKDYEVMMQIDCEVMDTRILHIKSSSVPPYLLLLTQKSGRQSAVFWAAGYSAGAVGHHWRQGGQAPFPTIHFL", "length": 679, "header": "tr|A0A8V0YGP2-1|A0A8V0YGP2_CHICK Isoform 1 of Activating transcription factor 6 beta OS=Gallus gallus OX=9031 GN=ATF6B PE=3 SV=1 CANONICAL=A0A8V0YGP2-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YGP2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGP2/entry#A0A8V0YGP2-1", "sequence": { "sequence": "MAAAKAEWEPAGLLPAAGGGLDWETVLGEELGELLGAAESRRASRDEPDSFQENDLYNFHFDLDLMSWDSDLWNITSHSYSDANVKTEPLSPAPSTCSVPSPSSVDSPVQNVPDDMDFSCSSQMSPISLYCKSSRSPASPEGDAEKKPIVGVTSRSANNSVKTLKRCGQTASRPSIQPKPLLPAVPEAQANIGIPAKTIIIQTLPTLVPLPKHQPVVNIQPAPPKGPSVVLPQPAVVQLQASGVLPASQPVIAVTGGTTQLHNHTVGALPPTAGNGSANGKITVAKPLLQSTTPAVGLDLNVLRRQQRMIKNRESAFQSRKKKKEYMLGLEARLEAALLENEKLKKENSTLKRQLDEVVLENQKLKVSSPKRRTLCVMVILAFIMLNYGPLSVFEKDPNGVDSAVSSNHRTRNLLEFSASKEPSPAQKIPIDIISEKINRYDNSVSDNKALMIVSEEPLLYISPPPPPCQPLINRTESQRLNHELRGWVHRHEVERTRSRRKSNNQHQKARVMQSSVSQKVHSQLMTMPYTDTSLRNSGNELQVYYASPRSYQDFFEAIHRKEDTFYVVSFRRDHLLLPATTHNKTRRPKMSIVLPAVNINENVINGKDYEVMMQIDCEVMDTRILHIKSSSVPPYLLLLTQKSGRQSAVFWAAGYSAGAVGHHWRQGGQAPFPTIHFL", "length": 679, "header": "tr|A0A8V0YGP2-1|A0A8V0YGP2_CHICK Isoform 1 of Activating transcription factor 6 beta OS=Gallus gallus OX=9031 GN=ATF6B PE=3 SV=1 CANONICAL=A0A8V0YGP2-1" }, "locus": { "chromosome": "8", "start_pos": 3791619, "end_pos": 3720368, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031051.1", "url": "https://www.ensembl.org/id/ENSGALT00010031051.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018051.1", "url": "https://www.ensembl.org/id/ENSGALP00010018051.1" } ] } }, { "isoform_ac": "A0A8V0YJM8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGP2/entry#A0A8V0YJM8-1", "sequence": { "sequence": "MAAAKAEWEPAGLLPAAGGGLDWETVLGEELGELLGAAESRRASRDEPDSFQENDLYNFHFDLDLMSWDSDLWNITSHSYSDANVKTEPLSPAPSTCSVPSPSSVDSPVQNVPDDMDFSCSSQMSPISLYCKSSRSPASPEGDAEKKPIVGVTSRSANNSVKTLKRCGQTASRPSIQPKPLLPAVPEAQANIGIPAKTIIIQTLPTLVPLPKHQPVVNIQPAPPKGPSVVLPQPAVVQLQASGVLPASQPVIAVTGGTTQLHNHTVGALPPTAGNGSANGKITVAKPLLQSTTPAVGLDLNVLRRQQRMIKNRESAFQSRKKKKEYMLGLEARLEAALLENEKLKKENSTLKRQLDEVVLENQKLKVSSPKRRTLCVMVILAFIMLNYGPLSVFEKDPNGVDSAVSSNHRTRNLLEFSASKEPSPAQKIPIDIISEKINRYDNSVSDNKALMIVSEEPLLYISPPPPPCQPLINRTESQRLNHELRGWVHRHEVERTRSRRKSNNQHQKARVMQSSVSQKVHSQLMTMPYTDTSLSRNSGNELQVYYASPRSYQDFFEAIHRKEDTFYVVSFRRDHLLLPATTHNKTRRPKMSIVLPAVNINGGAGCKRVQPWLSAVIQNQS", "length": 622, "header": "tr|A0A8V0YJM8-1|A0A8V0YJM8_CHICK Computationally mapped isoform of Activating transcription factor 6 beta OS=Gallus gallus OX=9031 GN=ATF6B PE=3 SV=1 CANONICAL=A0A8V0YGP2-1" }, "locus": { "chromosome": "8", "start_pos": 3788336, "end_pos": 3720368, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031042.1", "url": "https://www.ensembl.org/id/ENSGALT00010031042.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018045.1", "url": "https://www.ensembl.org/id/ENSGALP00010018045.1" } ] } }, { "isoform_ac": "A0A8V0YPH3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGP2/entry#A0A8V0YPH3-1", "sequence": { "sequence": "MAAAKAEWEPAGLLPAAGGGLDWETVLGEELGELLGAAESRRASRDEPDSFQENDLYNFHFDLDLMSWDSDLWNITSHSYSDANVKTEPLSPAPSTCSVPSPSSVDSPVQNVPDDMDFSCSSQMSPISLYCKSSRSPASPEGDAEKKPIVGVTSRSANNSVKTLKRCGQTASRPSIQPKPLLPAVPEAQANIGIPAKTIIIQTLPTLVPLPKHQPVVNIQPAPPKGPSVVLPQPAVVQLQASGVLPASQPVIAVTGGTTQLHNHTVGALPPTAGNGSANGKITVAKPLLQSTTPAVGLDLNVLRRQQRMIKNRESAFQSRKKKKEYMLGLEARLEAALLENEKLKKENSTLKRQLDEVVLENQKLKVSSPKRRTLCVMVILAFIMLNYGPLSVFEKDPNGVDSAVSSNHRTRNLLEFSASKEPSPAQKIPIDIISEKINRYDNSVSDNKALMIVSEEPLLYISPPPPPCQPLINRTESQRLNHELRGWVHRHEVERTRSRRKSNNQHQKARVMQSSVSQKVHSQLMTMPYTDTSLSRNSGNELQVYYASPRSYQDFFEAIHRKEDTFYVVSFRRDHLLLPATTHNKTRRPKMSIVLPAVNINENVINGKDYEVMMQIDCEVMDTRILHIKSSSVPPYLREQRRNDTNTFYSSSSSVSETPHALRAIVKSLQ", "length": 671, "header": "tr|A0A8V0YPH3-1|A0A8V0YPH3_CHICK Computationally mapped isoform of Activating transcription factor 6 beta OS=Gallus gallus OX=9031 GN=ATF6B PE=3 SV=1 CANONICAL=A0A8V0YGP2-1" }, "locus": { "chromosome": "8", "start_pos": 3789629, "end_pos": 3720368, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031047.1", "url": "https://www.ensembl.org/id/ENSGALT00010031047.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018048.1", "url": "https://www.ensembl.org/id/ENSGALP00010018048.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-381033", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-381033", "resource": "Reactome", "description": "ATF6 (ATF6-alpha) activates chaperones" }, { "id": "R-GGA-9909505", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9909505", "resource": "Reactome", "description": "Modulation of host responses by IFN-stimulated genes" } ], "orthologs": [ { "uniprot_canonical_ac": "F6VAN0-1", "protein_name": "Cyclic AMP-dependent transcription factor ATF-6 alpha", "gene_name": "Atf6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MESPFSPVLPHGPDEDWESTLFAELGYFTDTDDVHFDAAHEAYENNFDHLNFDLDLMPWESDLWSPGSHFCSDMKAEPQPLSPASSSCSISSPRSTDSCSSTQHVPEELDLLSSSQSPLSLYGDSCNSPSSVEPLKEEKPVTGPGNKTEHGLTPKKKIQMSSKPSVQPKPLLLPAAPKTQTNASVPAKAIIIQTLPALMPLAKQQSIISIQPAPTKGQTVLLSQPTVVQLQSPAVLSSAQPVLAVTGGAAQLPNHVVNVLPAPVVSSPVNGKLSVTKPVLQSATRSMGSDIAVLRRQQRMIKNRESACQSRKKKKEYMLGLEARLKAALSENEQLKKENGSLKRQLDEVVSENQRLKVPSPKRRAVCVMIVLAFIMLNYGPMSMLEQESRRVKPSVSPANQRRHLLEFSAKEVKDTSDGDNQKDSYSYDHSVSNDKALMVLSEEPLLYMPPPPCQPLINTTESLRLNHELRGWVHRHEVERTKSRRMTNSQQKARILQGALEQGSNSQLMAVQYTETTSISRNSGSELQVYYASPGSYQGFFDAIRRRGDTFYVVSFRRDHLLLPATTHNKTTRPKMSIVLPAININDNVINGQDYEVMMQIDCQVMDTRILHIKSSSVPPYLRDHQRNQTSTFFGSPPTTTETTHVVSTIPESLQ", "length": 656 }, "evidence": [ { "id": "A0A8V0YGP2", "url": "https://omabrowser.org/oma/group/A0A8V0YGP2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "G3V909-1", "protein_name": "Cyclic AMP-dependent transcription factor ATF-6 alpha", "gene_name": "Atf6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MESPFSPVLPHGPGEDWESTLFAELGYFTDTDDVQFDAAHETYENNFDHLNFDLDLMPWESDIWSPSSHFCSDIKAEPQPLSPASSSCSVSSPRSTDSCSSTQHVPEELDLLSSSQSPLSLYGDSCHSPSSAEPLKEEKPVTGPGNKTEHGLTPKKKIQMSSKPSVQPKPLLLPAAPKTPANASVPAKTIIIQTLPALMPLAKQQSIISIQPAPTKGQTVLLSQPAVVQLQTPGVLPSAQPVLAVTGGATQLPNHVVNVVPAPVVNSPVNGKLCVTKPVLQSSTRSTGSDIAVLRRQQRMIKNRESACQSRKKKKEYMLGLEARLKAALSENEQLKKENGSLKRQLDQVVSENQRLKVPSPKRRAVCVMIVLAFIMLNYGPMSMLEQDSRRVKPSVSPANQRRHLLEFSAKEVKDTSDGDNQKNSYRYDHSVSNDKALMVLSEEPLLYIPPPPCQPLINTTESLRLNHELRGWVHRHEVERTKSRRMTNSQQKTRILQGALEQGSNSQLMAVQYTETTSISRNSGSELQVYYASPGSYQGFFDAIRRRGDTFYVVSFRRDHLLLPATTHNKTTRPKMSIVLPAININDNVINGQDYEVMMQIDCQVMDTRILHIKSSSVPPYLRDHQRNQTSTFFGSPPTATETTHVVSTLPESVQ", "length": 656 }, "evidence": [ { "id": "A0A8V0YGP2", "url": "https://omabrowser.org/oma/group/A0A8V0YGP2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P18850-1", "protein_name": "Cyclic AMP-dependent transcription factor ATF-6 alpha", "gene_name": "ATF6", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGEPAGVAGTMESPFSPGLFHRLDEDWDSALFAELGYFTDTDELQLEAANETYENNFDNLDFDLDLMPWESDIWDINNQICTVKDIKAEPQPLSPASSSYSVSSPRSVDSYSSTQHVPEELDLSSSSQMSPLSLYGENSNSLSSAEPLKEDKPVTGPRNKTENGLTPKKKIQVNSKPSIQPKPLLLPAAPKTQTNSSVPAKTIIIQTVPTLMPLAKQQPIISLQPAPTKGQTVLLSQPTVVQLQAPGVLPSAQPVLAVAGGVTQLPNHVVNVVPAPSANSPVNGKLSVTKPVLQSTMRNVGSDIAVLRRQQRMIKNRESACQSRKKKKEYMLGLEARLKAALSENEQLKKENGTLKRQLDEVVSENQRLKVPSPKRRVVCVMIVLAFIILNYGPMSMLEQDSRRMNPSVSPANQRRHLLGFSAKEAQDTSDGIIQKNSYRYDHSVSNDKALMVLTEEPLLYIPPPPCQPLINTTESLRLNHELRGWVHRHEVERTKSRRMTNNQQKTRILQGALEQGSNSQLMAVQYTETTSSISRNSGSELQVYYASPRSYQDFFEAIRRRGDTFYVVSFRRDHLLLPATTHNKTTRPKMSIVLPAININENVINGQDYEVMMQIDCQVMDTRILHIKSSSVPPYLRDQQRNQTNTFFGSPPAATEATHVVSTIPESLQ", "length": 670 }, "evidence": [ { "id": "A0A8V0YGP2", "url": "https://omabrowser.org/oma/group/A0A8V0YGP2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q5RH85-1", "protein_name": "Cyclic AMP-dependent transcription factor ATF-6 alpha", "gene_name": "atf6", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSSNLMLDLMNPSMSSKEVGDISIDQDGEWDISLFDELEDLGDADELLEALVKSVGYDTSVPDLNFGTEQPAWSSDGWRETSSPRSDGDVTVDSLSPNHTFSSVSSPASVEPQSPYSTHDEALSPDSWRSHPSPLSVCSDSSGFTEAPNEKKPSKRTNQTKAKPLQPAKRPIQVCPKVSIQPKPIITAVPISRPAAPLQTKIIIQPLQATVLPVVKPPPVTIQPAPPTGQLMQLPQPTQVLQLQTPQSMPTRVVTMPALAQDRPISLVAPVTTSPVVTMTLQNSTPDDDSNASRRQQRMIKNRESASLSRKKKKEYLMTLETRLKLALTENEKLKNENGTLKRQVEGLMSENSVLKATAPKRRAVCLMVVLVFLVVNLGPMSLLGGDRGSAFPATPVFNGRHLLGFSPESERNLDKPQTDPSNTVDRLEEGVSEQKALMVVKDPLYFRTPPPCQPPVNRTKCIKIAHELRGWVHRHEVERTKTRRMSNTQHRGRTFMKASSKQADVPQIMSQIQYTDSSEKNPGSELQVYYAPHRTYNDFFDELNRRGDTFYVISFRRDHLLLPATNHNKGSRPKMSVVLPAMNYNESIIKDKDYEVMMQIDCEVMDTKILHIKSSSIPPILRVNQTETSSFYHATPSNNQPAAPVGVLVGSS", "length": 653 }, "evidence": [ { "id": "A0A8V0YGP2", "url": "https://omabrowser.org/oma/group/A0A8V0YGP2/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGP2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGP2" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGP2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGP2" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGP2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGP2" } ], "pmid": "" }, { "name": "fibrillar center", "id": "GO:0001650", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001650", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGP2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGP2" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGP2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGP2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 8, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGP2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGP2" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGP2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGP2" } ], "pmid": "" }, { "name": "positive regulation of apoptotic process", "id": "GO:0043065", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043065", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGP2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGP2" } ], "pmid": "" }, { "name": "visual perception", "id": "GO:0007601", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007601", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGP2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGP2" } ], "pmid": "" }, { "name": "endoplasmic reticulum unfolded protein response", "id": "GO:0030968", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030968", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGP2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGP2" } ], "pmid": "" }, { "name": "eye development", "id": "GO:0001654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGP2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGP2" } ], "pmid": "" }, { "name": "positive regulation of ATF6-mediated unfolded protein response", "id": "GO:1903893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903893", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGP2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGP2" } ], "pmid": "" }, { "name": "response to unfolded protein", "id": "GO:0006986", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006986", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGP2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGP2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 8, "go_terms": [ { "name": "enzyme binding", "id": "GO:0019899", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019899", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGP2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGP2" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGP2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGP2" } ], "pmid": "" }, { "name": "protein heterodimerization activity", "id": "GO:0046982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046982", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGP2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGP2" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGP2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGP2" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGP2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGP2" } ], "pmid": "" }, { "name": "DNA-binding transcription activator activity, RNA polymerase II-specific", "id": "GO:0001228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001228", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGP2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGP2" } ], "pmid": "" }, { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGP2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGP2" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGP2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGP2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 158, "end_pos": 160, "annotation": "n_glycosylation_sequon" }, { "start_pos": 263, "end_pos": 265, "annotation": "n_glycosylation_sequon" }, { "start_pos": 275, "end_pos": 277, "annotation": "n_glycosylation_sequon" }, { "start_pos": 348, "end_pos": 350, "annotation": "n_glycosylation_sequon" }, { "start_pos": 474, "end_pos": 476, "annotation": "n_glycosylation_sequon" }, { "start_pos": 584, "end_pos": 586, "annotation": "n_glycosylation_sequon" }, { "start_pos": 74, "end_pos": 76, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YGP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGP2" }, { "id": "PS50217", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50217" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "BZIP", "eco_id": "ECO_0000259", "start_pos": 302, "end_pos": 365, "start_aa": "Val", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 158, "end_pos": 160 }, { "start_pos": 263, "end_pos": 265 }, { "start_pos": 275, "end_pos": 277 }, { "start_pos": 348, "end_pos": 350 }, { "start_pos": 474, "end_pos": 476 }, { "start_pos": 584, "end_pos": 586 }, { "start_pos": 74, "end_pos": 76 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YGQ5-1", "uniprot_ac": "A0A8V0YGQ5", "uniprot_id": "A0A8V0YGQ5_CHICK", "mass": { "chemical_mass": 41225.0, "monoisotopic_mass": 41225.0 }, "refseq": {}, "gene_names": [ { "name": "ST13P5", "type": "recommended", "evidence": [ { "id": "A0A8V0YGQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGQ5" } ] } ], "protein_names": [ { "name": "Suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) pseudo 5", "type": "synonym", "evidence": [ { "id": "A0A8V0YGQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGQ5/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "One HIP oligomer binds the ATPase domains of at least two HSC70 molecules dependent on activation of the HSC70 ATPase by HSP40. Stabilizes the ADP state of HSC70 that has a high affinity for substrate protein. Through its own chaperone activity, it may contribute to the interaction of HSC70 with various target proteins.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGQ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGQ5#function" }, { "database": "UniProtKB", "id": "ARBA00037033", "url": "https://www.uniprot.org/uniprotkb/ARBA00037033#function" }, { "database": "UniProtKB", "id": "A0A8V0YGS3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGS3#function" }, { "database": "UniProtKB", "id": "A0A8V0YHQ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHQ6#function" }, { "database": "UniProtKB", "id": "F1NH21", "url": "https://www.uniprot.org/uniprotkb/F1NH21#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGQ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGQ5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ST13P5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGQ5", "locus": { "chromosome": "1", "start_pos": 49967664, "end_pos": 49945555, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012948", "url": "https://www.ensembl.org/id/ENSGALG00010012948" } ] } } ], "crossref": [ { "id": "A0A8V0YGQ5", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YGQ5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000012007", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000012007", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd14438", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14438", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "418003", "url": "https://www.ncbi.nlm.nih.gov/gene/418003", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006636", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006636", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011990", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011990", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019734", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019734", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034649", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034649", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041243", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041243", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:418003", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418003", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YEKRRYK", "url": "https://omabrowser.org/oma/group/YEKRRYK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YGQ5", "url": "https://www.orthodb.org/?gene=A0A8V0YGQ5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YGS3", "url": "https://www.orthodb.org/?gene=A0A8V0YGS3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YHQ6", "url": "https://www.orthodb.org/?gene=A0A8V0YHQ6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NH21", "url": "https://www.orthodb.org/?gene=F1NH21", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45883", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45883", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45883:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45883:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13181", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13181", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17830", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17830", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF18253", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18253", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YGQ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGQ5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YGQ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGQ5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YGS3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGS3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YGS3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGS3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHQ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHQ6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHQ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHQ6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NH21", "url": "https://www.uniprot.org/uniprotkb/F1NH21", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NH21-1", "url": "https://www.uniprot.org/uniprotkb/F1NH21-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDSRKLSELRAFVRLCKQNPGLLHTEELGFLREWVESMGGTIPPAPASTSTDETSKGKAEEQPEEPVKSPEPESEESDLEIDNEGVIEPDNDDPQEMGDENVEVTEEMMDQANEKKMEAINALSEGDLQKAVNLFTDAIKLNPCLAILYAKRASVFVKLQKPNAAIRDCDRAIKINPDSAQTYKWRGKAHRLLGHWEEAAHDLALACKLDYDEDASAMLKEVQPRAQKIAEHRRKYERKREEKEIKERMERVKKAREEHERAQREEEARRQAGGAQFGGFPGGFPGGFPGAMPGGMPGMAGMPGLNEILSDPEVLAAMQDPEVMAAFQDVAQNPANMSKYQNNPKLGQKNWPTRKWQRWDKSEELTG", "length": 367, "header": "tr|A0A8V0YGQ5-1|A0A8V0YGQ5_CHICK Isoform 1 of Suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) pseudo 5 OS=Gallus gallus OX=9031 GN=ST13P5 PE=3 SV=1 CANONICAL=A0A8V0YGQ5-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YGQ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGQ5/entry#A0A8V0YGQ5-1", "sequence": { "sequence": "MDSRKLSELRAFVRLCKQNPGLLHTEELGFLREWVESMGGTIPPAPASTSTDETSKGKAEEQPEEPVKSPEPESEESDLEIDNEGVIEPDNDDPQEMGDENVEVTEEMMDQANEKKMEAINALSEGDLQKAVNLFTDAIKLNPCLAILYAKRASVFVKLQKPNAAIRDCDRAIKINPDSAQTYKWRGKAHRLLGHWEEAAHDLALACKLDYDEDASAMLKEVQPRAQKIAEHRRKYERKREEKEIKERMERVKKAREEHERAQREEEARRQAGGAQFGGFPGGFPGGFPGAMPGGMPGMAGMPGLNEILSDPEVLAAMQDPEVMAAFQDVAQNPANMSKYQNNPKLGQKNWPTRKWQRWDKSEELTG", "length": 367, "header": "tr|A0A8V0YGQ5-1|A0A8V0YGQ5_CHICK Isoform 1 of Suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) pseudo 5 OS=Gallus gallus OX=9031 GN=ST13P5 PE=3 SV=1 CANONICAL=A0A8V0YGQ5-1" }, "locus": { "chromosome": "1", "start_pos": 49964210, "end_pos": 49945716, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031066.1", "url": "https://www.ensembl.org/id/ENSGALT00010031066.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018061.1", "url": "https://www.ensembl.org/id/ENSGALP00010018061.1" } ] } }, { "isoform_ac": "A0A8V0YGS3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGQ5/entry#A0A8V0YGS3-1", "sequence": { "sequence": "MDSRKLSELRAFVRLCKQNPGLLHTEELGFLREWVESMGGTIPPAPASTSTDETSKGKAEEQPEEPVKSPEPESEESDLEIDNEGVIEPDNDDPQEMGDENVEVTEEMMDQANEKKMEAINALSEGDLQKAVNLFTDAIKLNPCLAILYAKRASVFVKLQKPNAAIRDCDRAIKINPDSAQTYKWRGKAHRLLGHWEEAAHDLALACKLDYDEDASAMLKEVQPRAQKIAEHRRKYERKREEKEIKERMERVKKAREEHERAQREEEARRQAGGAQFGGFPGGFPGGFPGAMPGGMPGMAGMPGLNEILSDPEVLAAMQDPEVMAAFQDVAQNPANMSKYQNNPKCYLVR", "length": 350, "header": "tr|A0A8V0YGS3-1|A0A8V0YGS3_CHICK Computationally mapped isoform of Suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) pseudo 5 OS=Gallus gallus OX=9031 GN=ST13P5 PE=3 SV=1 CANONICAL=A0A8V0YGQ5-1" }, "locus": { "chromosome": "1", "start_pos": 49966029, "end_pos": 49945716, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031083.1", "url": "https://www.ensembl.org/id/ENSGALT00010031083.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018077.1", "url": "https://www.ensembl.org/id/ENSGALP00010018077.1" } ] } }, { "isoform_ac": "A0A8V0YHQ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGQ5/entry#A0A8V0YHQ6-1", "sequence": { "sequence": "MDSRKLSELRAFVRLCKQNPGLLHTEELGFLREWVERKSMGGTIPPAPASTSTDETSKGKAEEQPEEPVKSPEPESEESDLEIDNEGVIEPDNDDPQEMGDENVEVTEEMMDQANEKKMEAINALSEGDLQKAVNLFTDAIKLNPCLAILYAKRASVFVKLQKPNAAIRDCDRAIKINPDSAQTYKWRGKAHRLLGHWEEAAHDLALACKLDYDEDASAMLKEVQPRAQKIAEHRRKYERKREEKEIKERMERVKKAREEHERAQREEEARRQAGGAQFGGFPGGFPGGFPGAMPGGMPGMAGMPGLNEILSDPEVLAAMQDPEVMAAFQDVAQNPANMSKYQNNPKVMSLITKLSAKFGSKP", "length": 363, "header": "tr|A0A8V0YHQ6-1|A0A8V0YHQ6_CHICK Computationally mapped isoform of Suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) pseudo 5 OS=Gallus gallus OX=9031 GN=ST13P5 PE=3 SV=1 CANONICAL=A0A8V0YGQ5-1" }, "locus": { "chromosome": "1", "start_pos": 49963734, "end_pos": 49945716, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031074.1", "url": "https://www.ensembl.org/id/ENSGALT00010031074.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018069.1", "url": "https://www.ensembl.org/id/ENSGALP00010018069.1" } ] } }, { "isoform_ac": "F1NH21-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGQ5/entry#F1NH21-1", "sequence": { "sequence": "MDSRKLSELRAFVRLCKQNPGLLHTEELGFLREWVESMGGTIPPAPASTSTDETSKGKAEEQPEEPVKSPEPESEESDLEIDNEGVIEPDNDDPQEMGDENVEVTEEMMDQANEKKMEAINALSEGDLQKAVNLFTDAIKLNPCLAILYAKRASVFVKLQKPNAAIRDCDRAIKINPDSAQTYKWRGKAHRLLGHWEEAAHDLALACKLDYDEDASAMLKEVQPRAQKIAEHRRKYERKREEKEIKERMERVKKAREEHERAQREEEARRQAGGAQFGGFPGGFPGGFPGAMPGGMPGMAGMPGLNEILSDPEVLAAMQDPEVMAAFQDVAQNPANMSKYQNNPKVMSLITKLSAKFGSKP", "length": 361, "header": "tr|F1NH21-1|F1NH21_CHICK Computationally mapped isoform of Suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) pseudo 5 OS=Gallus gallus OX=9031 GN=ST13P5 PE=3 SV=1 CANONICAL=A0A8V0YGQ5-1" }, "locus": { "chromosome": "1", "start_pos": 49963734, "end_pos": 49945716, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031080.1", "url": "https://www.ensembl.org/id/ENSGALT00010031080.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018075.1", "url": "https://www.ensembl.org/id/ENSGALP00010018075.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:418003", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418003", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "C4NYP8-1", "protein_name": "Hsc70-interacting protein 1", "gene_name": "HIP", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MAFTMQTGDLKKLKYFIDFALENPTFLNMPQLQFVKDFVEKFGGTVPPGQFNGGSAGGKCPFGGVAGAKANEPANAPEDSEDEKSLSDPESDVELDMEGVIEADSDPAQPMGNYSKKATEEEVEQASELRAQAASAYGQQKFDEAIALYTKAIELSPGNALFHAKRGQAFLKLKKPNACIRDCDVALELNSDLAAGYKFRGRARRLLGDFELAAHDLRQACKLDFDEETDEWLKEVTPNAKKIEQHRLKQERRQAERKIKERQRDQRRARKEQEKHNASSGGSSGEFSGGNPGNGNMSDILGAMSDPEVSAAIQDILSNPGNITKYASNPKIYNLIKKIVPGGDVGAAFGQAGEKAGKPSEPKPKKDSADFVDDGLD", "length": 377 }, "evidence": [ { "id": "A0A8V0YGQ5", "url": "https://omabrowser.org/oma/group/A0A8V0YGQ5/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "P50502-1", "protein_name": "Hsc70-interacting protein", "gene_name": "ST13", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDPRKVNELRAFVKMCKQDPSVLHTEEMRFLREWVESMGGKVPPATQKAKSEENTKEEKPDSKKVEEDLKADEPSSEESDLEIDKEGVIEPDTDAPQEMGDENAEITEEMMDQANDKKVAAIEALNDGELQKAIDLFTDAIKLNPRLAILYAKRASVFVKLQKPNAAIRDCDRAIEINPDSAQPYKWRGKAHRLLGHWEEAAHDLALACKLDYDEDASAMLKEVQPRAQKIAEHRRKYERKREEREIKERIERVKKAREEHERAQREEEARRQSGAQYGSFPGGFPGGMPGNFPGGMPGMGGGMPGMAGMPGLNEILSDPEVLAAMQDPEVMVAFQDVAQNPANMSKYQSNPKVMNLISKLSAKFGGQA", "length": 369 }, "evidence": [ { "id": "A0A8V0YGQ5", "url": "https://omabrowser.org/oma/group/A0A8V0YGQ5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q86DS1-1", "protein_name": "Hsc70-interacting protein 2", "gene_name": "HIP-R", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MAFTMQTGDLKKLKYFIDFALENPTFLNMPQLQFVKDFVEKFGGTVPPGQFNGGSAGGKCPFGGVAGAKANEPANAPEDSEDEKSLSDPESDVELDMEGVIEADSDPAQPMGNYSKKATEEEVEQASELRAQAASAYGQQKFDEAIALYTKAIELSPGNALFHAKRGQAFLKLKKPNACIRDCDVALELNSDLAAGYKFRGRARRLLGDFELAAHDLRQACKLDFDEETDEWLKEVTPNAKKIEQHRLKQERRQAERKIKERQRDQRRARKEQEKHNASSGGSSGEFSGGNPGNGNMSDILGAMSDPEVSAAIQDILSNPGNITKYASNPKIYNLIKKIVPGGDVGAAFGQAGEKAGKPSEPKPKKDSADFVDDGLD", "length": 377 }, "evidence": [ { "id": "A0A8V0YGQ5", "url": "https://omabrowser.org/oma/group/A0A8V0YGQ5/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q93YR3-1", "protein_name": "FAM10 family protein At4g22670", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MDSTKLSELKVFIDQCKSDPSLLTTPSLSFFRDYLESLGAKIPTGVHEEDKDTKPRSFVVEESDDDMDETEEVKPKVEEEEEEDEIVESDVELEGDTVEPDNDPPQKMGDSSVEVTDENREAAQEAKGKAMEALSEGNFDEAIEHLTRAITLNPTSAIMYGNRASVYIKLKKPNAAIRDANAALEINPDSAKGYKSRGMARAMLGEWAEAAKDLHLASTIDYDEEISAVLKKVEPNAHKLEEHRRKYDRLRKEREDKKAERDRLRRRAEAQAAYDKAKKEEQSSSSRPSGGGFPGGMPGGFPGGMPGGFPGGMGGMPGGFPGGMGGMGGMPGGFPGGMGGGMPAGMGGGMPGMGGGMPAGMGGGGMPGAGGGMPGGGGMPGGMDFSKILNDPELMTAFSDPEVMAALQDVMKNPANLAKHQANPKVAPVIAKMMGKFAGPQ", "length": 441 }, "evidence": [ { "id": "A0A8V0YGQ5", "url": "https://omabrowser.org/oma/group/A0A8V0YGQ5/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q99L47-1", "protein_name": "Hsc70-interacting protein", "gene_name": "St13", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDPRKVSELRAFVKMCRQDPSVLHTEEMRFLREWVESMGGKVPPATHKAKSEENTKEEKRDKTTEENIKTEELSSEESDLEIDNEGVIEPDTDAPQEMGDENAEITEEMMDEANEKKGAAIEALNDGELQKAIDLFTDAIKLNPRLAILYAKRASVFVKLQKPNAAIRDCDRAIEINPDSAQPYKWRGKAHRLLGHWEEAAHDLALACKLDYDEDASAMLREVQPRAQKIAEHRRKYERKREEREIKERIERVKKAREEHERAQREEEARRQSGSQYGSFPGGFPGGMPGNFPGGMPGMGGAMPGMAGMAGMPGLNEILSDPEVLAAMQDPEVMVAFQDVAQNPSNMSKYQSNPKVMNLISKLSAKFGGQS", "length": 371 }, "evidence": [ { "id": "A0A8V0YGQ5", "url": "https://omabrowser.org/oma/group/A0A8V0YGQ5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGQ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGQ5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "protein dimerization activity", "id": "GO:0046983", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046983", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGQ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGQ5" } ], "pmid": "" }, { "name": "Hsp70 protein binding", "id": "GO:0030544", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030544", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGQ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGQ5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "protein folding", "id": "GO:0006457", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006457", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGQ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGQ5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 336, "end_pos": 338, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YGQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGQ5" }, { "id": "SM00727", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00727" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "STI1", "eco_id": "ECO_0000259", "start_pos": 311, "end_pos": 350, "start_aa": "Asp", "end_aa": "Asn", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 336, "end_pos": 338 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YGR9-1", "uniprot_ac": "A0A8V0YGR9", "uniprot_id": "A0A8V0YGR9_CHICK", "mass": { "chemical_mass": 149157.0, "monoisotopic_mass": 149157.0 }, "refseq": { "ac": "NP_001383941", "name": "ribosome biogenesis protein BMS1 homolog isoform 2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001383941" }, "gene_names": [ { "name": "BMS1", "type": "recommended", "evidence": [ { "id": "A0A8V0YGR9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGR9" } ] }, { "name": "BMS1L", "type": "synonym", "evidence": [ { "id": "NP_001383941", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001383941" } ] }, { "name": "BMS1", "type": "synonym", "evidence": [ { "id": "NP_001383941", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001383941" } ] } ], "protein_names": [ { "name": "BMS1 homolog, ribosome assembly protein", "type": "synonym", "evidence": [ { "id": "NP_001383941", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001383941" } ] }, { "name": "BMS1, ribosome biosis factor", "type": "synonym", "evidence": [ { "id": "A0A8V0YGR9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGR9/entry#names_and_taxonomy" } ] }, { "name": "BMS1-like, ribosome assembly protein", "type": "synonym", "evidence": [ { "id": "NP_001383941", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001383941" } ] }, { "name": "ribosome biogenesis protein BMS1 homolog isoform 2", "type": "synonym", "evidence": [ { "id": "NP_001383941", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001383941" } ] }, { "name": "ribosome biogenesis protein BMS1 homolog", "type": "synonym", "evidence": [ { "id": "NP_001383941", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001383941" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: SRR13267654.6256.1, SRR13267661.18417.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA103992290, SAMEA103992323 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000227.1. Transcript Variant: This variant (2) has the long twelfth intron. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001383941", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001383941" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGR9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGR9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "BMS1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGR9", "locus": { "chromosome": "6", "start_pos": 5745070, "end_pos": 5765857, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010011146", "url": "https://www.ensembl.org/id/ENSGALG00010011146" } ] } } ], "crossref": [ { "id": "cd01882", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01882", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "423633", "url": "https://www.ncbi.nlm.nih.gov/gene/423633", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR007034", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007034", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012948", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012948", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR030387", "url": "https://www.ebi.ac.uk/interpro/entry/IPR030387", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037875", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037875", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039761", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039761", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YGR9", "url": "https://www.orthodb.org/?gene=A0A8V0YGR9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12858", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12858", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12858:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12858:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04950", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04950", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08142", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08142", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-6791226", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6791226", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001383941", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001383941", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "19669", "url": "https://www.rhea-db.org/rhea/19669", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YGR9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGR9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YGR9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGR9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEEKEKKKHRAKHSGPKAEKKRKRHLNDLGIGEEEDARKRNPKAFTVQSAVRMARTFHRTQDLKTKKHHIPVVDRTPLEPPPVVVVVVGPPKVGKSTLIKCLIKNFTRQKLVEIRGPVTIVSGKKRRLTIIECGCDVNTMIDLAKVADLVLMLIDASFGFEMETFEFLNICQVHGFPKIMGILTHLDTFKNNKQLKKTKKRLKHRFWTEVYPGAKLFYLSGMVHGEYQKQEIHNLGRFISVMKFRPLTWQTSHPYVLADRMEDLTNPEDIRLNPKCDRKISLYGYLRGAYLKNKSQIHMPGVGDFTVSDVSFLPDPCALPEQQKKRSLSEKEKLIYAPLSGVGGIVYDKDAVYIDLGGSHAHENEEEEVRPNHELVQSLISTHSAIDTKMASSKVSLFMDSTPLGSEDVGQEIVMPKEERQMDLKTGRVRRKALFDEEEKKDDDDDDDAVSDEEDEQEEEAMSEGGSDGDDEDDAEEESDEELLEAKMAPGSAKRLRTEVAKEETVSELPAFADSDDDLEMSSEEGKAASEEDETEEDDDDDDDEERTYGNDSSDSEFEAGSKGLVESEQNEVVNEDKETKSQLLVRSLKKKSLLTTDSGNCTAEEASESEVESLSEGDDEEKSHDELEAEVSDRKGFQHPQPKKADRTRPAEPESIEAEDDDVEDLLREEEEYEEKTDFSADTAGALKWKEDLTQKAAQAFLRQQQATPNLRKLVYGTAVEDEDKEGEDADDELGGLFHVSRPDKESKQKANGLDCSKFLVEKPQDWDLEEVMSSIRDCFVTGKWEEDKDAAKLLEEDELYGDFEDLETGVVHKGRPATEGDESENEEENDGKKSKPEAEEEEAKKERLDKKRKLKEMFDAEYDEGDATYFDDLKEEMHKQAQLNKTEFEDQDDETRVQYEGFRPGMYVRIEIENVPCEFVLNFDPHYPIILGGLGNSEGNVGYVQLRLKKHRWYKKILKTRDPLILSLGWRRFQTIPMFYIEDHNGRHRLLKYTPQHMHCGATFWGPITPQGTGFLAVQSVSGTTPDFRIAATGVVLDLDKSITVVKKLKLTGFPFKIFKNTSFIKGMFNSQLEVAKFEGAAIRTVSGIRGQIKKALRAPAGAFRATFEDKLLMSDIVFVRTWYPVSIPKFYNPVTSLLKPAGEKDSWKGMRTTGQLRHDQGIKLKQNKDSLYKPIVREKRHFNKLHIPKALQKALPFKNKPKNLEKKGKTPKDQWRPAVIMEPHEKKISALLNALSTVNNYKIKKAKVKHRQQMKEYIKVKQKEEEQKLKRQKEAKKKIYRILGQREKKRQKSSLKGSSEGAKSV", "length": 1308, "header": "tr|A0A8V0YGR9-1|A0A8V0YGR9_CHICK Isoform 1 of BMS1, ribosome biosis factor OS=Gallus gallus OX=9031 GN=BMS1 PE=1 SV=1 CANONICAL=A0A8V0YGR9-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YGR9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGR9/entry#A0A8V0YGR9-1", "sequence": { "sequence": "MEEKEKKKHRAKHSGPKAEKKRKRHLNDLGIGEEEDARKRNPKAFTVQSAVRMARTFHRTQDLKTKKHHIPVVDRTPLEPPPVVVVVVGPPKVGKSTLIKCLIKNFTRQKLVEIRGPVTIVSGKKRRLTIIECGCDVNTMIDLAKVADLVLMLIDASFGFEMETFEFLNICQVHGFPKIMGILTHLDTFKNNKQLKKTKKRLKHRFWTEVYPGAKLFYLSGMVHGEYQKQEIHNLGRFISVMKFRPLTWQTSHPYVLADRMEDLTNPEDIRLNPKCDRKISLYGYLRGAYLKNKSQIHMPGVGDFTVSDVSFLPDPCALPEQQKKRSLSEKEKLIYAPLSGVGGIVYDKDAVYIDLGGSHAHENEEEEVRPNHELVQSLISTHSAIDTKMASSKVSLFMDSTPLGSEDVGQEIVMPKEERQMDLKTGRVRRKALFDEEEKKDDDDDDDAVSDEEDEQEEEAMSEGGSDGDDEDDAEEESDEELLEAKMAPGSAKRLRTEVAKEETVSELPAFADSDDDLEMSSEEGKAASEEDETEEDDDDDDDEERTYGNDSSDSEFEAGSKGLVESEQNEVVNEDKETKSQLLVRSLKKKSLLTTDSGNCTAEEASESEVESLSEGDDEEKSHDELEAEVSDRKGFQHPQPKKADRTRPAEPESIEAEDDDVEDLLREEEEYEEKTDFSADTAGALKWKEDLTQKAAQAFLRQQQATPNLRKLVYGTAVEDEDKEGEDADDELGGLFHVSRPDKESKQKANGLDCSKFLVEKPQDWDLEEVMSSIRDCFVTGKWEEDKDAAKLLEEDELYGDFEDLETGVVHKGRPATEGDESENEEENDGKKSKPEAEEEEAKKERLDKKRKLKEMFDAEYDEGDATYFDDLKEEMHKQAQLNKTEFEDQDDETRVQYEGFRPGMYVRIEIENVPCEFVLNFDPHYPIILGGLGNSEGNVGYVQLRLKKHRWYKKILKTRDPLILSLGWRRFQTIPMFYIEDHNGRHRLLKYTPQHMHCGATFWGPITPQGTGFLAVQSVSGTTPDFRIAATGVVLDLDKSITVVKKLKLTGFPFKIFKNTSFIKGMFNSQLEVAKFEGAAIRTVSGIRGQIKKALRAPAGAFRATFEDKLLMSDIVFVRTWYPVSIPKFYNPVTSLLKPAGEKDSWKGMRTTGQLRHDQGIKLKQNKDSLYKPIVREKRHFNKLHIPKALQKALPFKNKPKNLEKKGKTPKDQWRPAVIMEPHEKKISALLNALSTVNNYKIKKAKVKHRQQMKEYIKVKQKEEEQKLKRQKEAKKKIYRILGQREKKRQKSSLKGSSEGAKSV", "length": 1308, "header": "tr|A0A8V0YGR9-1|A0A8V0YGR9_CHICK Isoform 1 of BMS1, ribosome biosis factor OS=Gallus gallus OX=9031 GN=BMS1 PE=1 SV=1 CANONICAL=A0A8V0YGR9-1" }, "locus": { "chromosome": "6", "start_pos": 5765515, "end_pos": 5745361, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026652.1", "url": "https://www.ensembl.org/id/ENSGALT00010026652.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015203.1", "url": "https://www.ensembl.org/id/ENSGALP00010015203.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-6791226", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6791226", "resource": "Reactome", "description": "Major pathway of rRNA processing in the nucleolus and cytosol" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGR9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGR9" } ], "pmid": "" }, { "name": "GTPase activity", "id": "GO:0003924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003924", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGR9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGR9" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGR9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGR9" } ], "pmid": "" }, { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGR9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGR9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGR9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGR9" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGR9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGR9" } ], "pmid": "" }, { "name": "chromosome", "id": "GO:0005694", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005694", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGR9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGR9" } ], "pmid": "" }, { "name": "90S preribosome", "id": "GO:0030686", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030686", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGR9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGR9" } ], "pmid": "" }, { "name": "small-subunit processome", "id": "GO:0032040", "url": 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protein 10", "type": "recommended", "evidence": [ { "id": "A0A8V0YGT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGT7/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Scaffold protein that plays an important role in mediating the activation of NF-kappa-B via BCL10 or EGFR.", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PZX1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PZX1#function" }, { "database": "UniProtKB", "id": "ARBA00056468", "url": "https://www.uniprot.org/uniprotkb/ARBA00056468#function" }, { "database": "UniProtKB", "id": "A0A8V0YGS1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGS1#function" }, { "database": "UniProtKB", "id": "A0A8V0YGT7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGT7#function" }, { "database": "UniProtKB", "id": "A0A8V0YMY9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMY9#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGT7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGT7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CARD10", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGT7", "locus": { "chromosome": "1", "start_pos": 51292519, "end_pos": 51263999, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010014193", "url": "https://www.ensembl.org/id/ENSGALG00010014193" } ] } } ], "crossref": [ { "id": "ENSGALG00000042365", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000042365", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "418041", "url": "https://www.ncbi.nlm.nih.gov/gene/418041", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001315", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001315", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011029", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011029", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036034", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036034", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PZX1", "url": "https://www.orthodb.org/?gene=A0A1D5PZX1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YGS1", "url": "https://www.orthodb.org/?gene=A0A8V0YGS1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YGT7", "url": "https://www.orthodb.org/?gene=A0A8V0YGT7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YMY9", "url": "https://www.orthodb.org/?gene=A0A8V0YMY9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YUZ7", "url": "https://www.orthodb.org/?gene=A0A8V0YUZ7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14559", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14559", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14559:SF12", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14559:SF12", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00619", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00619", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A1D5PZX1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PZX1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PZX1-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PZX1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YGS1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGS1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YGS1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGS1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YGT7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGT7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YGT7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGT7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YMY9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMY9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YMY9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMY9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YUZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUZ7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YUZ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUZ7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEQLSTGGGRRCWRLQCWGNDRRAAWPQGEEDVKEDAGICVAPAVCGGQDAKSRRTSPTQLSPCLPTPHCCISPSISPCNALCLLAVSPGHLGASASEPWALGCPPGRTCVFALPWPCLLTRGPSYLPGVNAWEGKTHLPPWRLPPLAAAFGGTGEDARTVAALLPAYPQPRGSCGSARPREWGTHGSVRSDRPVLELPLPGQCFSICGGNQGFLGLETTELGFVTQTMNHKARCTEEKLLVNHILPEINFSPEQQLEETDGPRAKQNPSPAPPGEQRSRGGCPRPAALENASLQACSLSEQEEEEDALWEKIESARHQLTRSLNPAKLTPYLRQCRVIDEQDEEEVLNSCRFPCKSNQTGYLMDILRRRGKRGYEAFLESLEFYYPEHYTRLTGREPAQRCSMILDEEGPEGLMQFLLVEVKKMRAQRKEHLLKEHQLQAKNQTLEQEQARLEQRLQELLKVQERCQRLREEWDSNSVELLRLKDENYMMAMRYAQLCEEKNMAVLRSRDLQLVVDQLKCKVTSLEEECSLLRKQASTMPQRETEERGHPDAVSELWAENQRLTASLQELQGMLQTPGEVPVPGSEQILLDILEHDWKEAQDDRQDLCQKLNSLQSELQWAEELRDKYLQEVEDLQLKYRTLQKDCDLYKHRMNTVLLQLEEIEKERDQAIQSRDGVQLQYSQSLIEKDQYRKRVRALEEERDELLSKLSRVEGLNSTLEAQLQRCRGNRSLGKMCSSSYSLCSNLSSTWSLVDKPSDLTSGLTDPLGVSPIIFPEDSAIHSMEGTPDSEKDINRLSTFPFPPCIGSILRRQREDRCMPYKSLSCGSFSSMEDTAGNSFVSIPPGAFSSSSSSIYTRVKSETCLSMLTSHQEISRRSLVVQLTSMGHPSSLSPREKRLGADISILGGNRTGIYVQWVKPGSQVESTGLREGCRLIKLRVPSLKEEVLSLENCTREVAYLSLLHWDEPSSLVFQLDLQGYQPLREALEEGKKFSGDSFYIRTNLSLLEPSDPYALCVKCREILHVTDTMYKGRLEWYCSRVDPLTMRDLDKGTVPNYSRAHQLLKIQEKVHIPGQQRSHRNNLKKRALDQLRLVKSKQQKSPEQPCQQLWLDPCSDPERSLKPYSLVHPVVVKTPRPVVLSPSCIAPRLIRNLLDLPTSRLDFHVCPAEKLTEGNPSAAHVQEPPVSRNAPQERRESSRVCMIREAMEKNKHCLLELGVQSVRDLIKREIYPIVIHVEVTEKNVRGLRSLLGQPGQRDAEVLKACRGAERALHALPCSWARVEPHAWSHAEELPKVVRGCIFQEQNRPLWVEDGDD", "length": 1316, "header": "tr|A0A8V0YGT7-1|A0A8V0YGT7_CHICK Isoform 1 of Caspase recruitment domain-containing protein 10 OS=Gallus gallus OX=9031 GN=CARD10 PE=4 SV=1 CANONICAL=A0A8V0YGT7-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PZX1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGT7/entry#A0A1D5PZX1-1", "sequence": { "sequence": "MAALENASLQACSLSEQEEEEDALWEKIESARHQLTRSLNPAKLTPYLRQCRVIDEQDEEEVLNSCRFPCKSNQTGYLMDILRRRGKRGYEAFLESLEFYYPEHYTRLTGREPAQRCSMILDEEGPEGLMQFLLVEVKKMRAQRKEHLLKEHQLQAKNQTLEQEQARLEQRLQELLKVQERCQRLREEWDSNSVELLRLKDENYMMAMRYAQLCEEKNMAVLRSRDLQLVVDQLKCKVTSLEEECSLLRKQASTMPQRETEERGHPDAVSELWAENQRLTASLQELQGMLQTPGEVPVPGSEQILLDILEHDWKEAQDDRQDLCQKLNSLQSELQWAEELRDKYLQEVEDLQLKYRTLQKDCDLYKHRMNTVLLQLEEIEKERDQAIQSRDGVQLQYSQSLIEKDQYRKRVRALEEERDELLSKLSRVEGLNSTLEAQLQRCRGNRSLGKMCSSSYSLCSNLSSTWSLVDKPSDLTSGLTDPLGVSPIIFPEDSAIHSMEGTPDSEKDINRLSTFPFPPCIGSILRRQREDRCMPYKSLSCGSFSSMEDTAGNSFVSIPPGAFSSSSSSIYTRVKSETCLSMLTSHQEISRRSLVVQLTSMGHPSSLSPREKRLGADISILGGNRTGIYVQWVKPGSQVESTGLREGCRLIKLRVPSLKEEVLSLENCTREVAYLSLLHWDEPSSLVFQLDLQGYQPLREALEEGKKFSGDSFYIRTNLSLLEPSDPYALCVKCREILHVTDTMYKGRLEWYCSRVDPLTMRDLDKGTVPNYSRAHQLLKIQEKVHIPGQQRSHRNNLKKRALDQLRLVKSKQQKSPEQPCQQLWLDPCSDPERSLKPYSLVHPVVVKTPRPVVLSPSCIAPRLIRNLLDLPTSRLDFHVCPAEKLTEGNPSAAHVQEPPVSRNAPQERRESSRVCMIREAMEKNKHCLLELGVQSVRDLIKREIYPIVIHVEVTEKNVRGLRSLLGQPGQRDAEVLKACRGAERALHALPCSWARVEPHAWSHAEELPKVVRGCIFQEQNRPLWVEDGDD", "length": 1031, "header": "tr|A0A1D5PZX1-1|A0A1D5PZX1_CHICK Computationally mapped isoform of Caspase recruitment domain-containing protein 10 OS=Gallus gallus OX=9031 GN=CARD10 PE=4 SV=1 CANONICAL=A0A8V0YGT7-1" }, "locus": { "chromosome": "1", "start_pos": 51291943, "end_pos": 51278780, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034156.1", "url": "https://www.ensembl.org/id/ENSGALT00010034156.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020067.1", "url": "https://www.ensembl.org/id/ENSGALP00010020067.1" } ] } }, { "isoform_ac": "A0A8V0YGS1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGT7/entry#A0A8V0YGS1-1", "sequence": { "sequence": "MEAPVGNQGFLGLETTELGFVTQTMNHKARCTEEKLLVNHILPEINFSPEQQLEETDGPRAKQNPSPAPPGEQRSRGGCPRPAALENASLQACSLSEQEEEEDALWEKIESARHQLTRSLNPAKLTPYLRQCRVIDEQDEEEVLNSCRFPCKSNQTGYLMDILRRRGKRGYEAFLESLEFYYPEHYTRLTGREPAQRCSMILDEEGPEGLMQFLLVEVKKMRAQRKEHLLKEHQLQAKNQTLEQEQARLEQRLQELLKVQERCQRLREEWDSNSVELLRLKDENYMMAMRYAQLCEEKNMAVLRSRDLQLVVDQLKCKVTSLEEECSLLRKQASTMPQRETEERGHPDAVSELWAENQRLTASLQELQGMLQTPGEVPVPGSEQILLDILEHDWKEAQDDRQDLCQKLNSLQSELQWAEELRDKYLQEVEDLQLKYRTLQKDCDLYKHRMNTVLLQLEEIEKERDQAIQSRDGVQLQYSQSLIEKDQYRKRVRALEEERDELLSKLSRVEGLNSTLEAQLQRCRGNRSLGKMCSSSYSLCSNLSSTWSLVDKPSDLTSGLTDPLGVSPIIFPEDSAIHSMEGTPDSEKDINRLSTFPFPPCIGSILRRQREDRCMPYKSLSCGSFSSMEDTAGNSFVSIPPGAFSSSSSSIYTRVKSETCLSMLTSHQEISRRSLVVQLTSMGHPSSLSPREKRLGADISILGGNRTGIYVQWVKPGSQVESTGLREGCRLIKLRVPSLKEEVLSLENCTREVAYLSLLHWDEPSSLVFQLDLQGYQPLREALEEGKKFSGDSFYIRTNLSLLEPSDPYALCVKCREILHVTDTMYKGRLEWYCSRVDPLTMRDLDKGTVPNYSRAHQLLKIQEKVHIPGQQRSHRNNLKKRALDQLRLVKSKQQKSPEQPCQQLWLDPCSDPERSLKPYSLVHPVVVKTPRPVVLSPSCIAPRLIRNLLDLPTSRLDFHVCPAEKLTEGNPSAAHVQEPPVSRNAPQERRESSRVCMIREAMEKNKHCLLELGVQSVRDLIKREIYPIVIHVEVTEKNVRGLRSLLGQPGQRDAEVLKACRGAERALHALPCSWARVEPHAWSHAEELPKVVRGCIFQEQNRPLWVEDGDD", "length": 1112, "header": "tr|A0A8V0YGS1-1|A0A8V0YGT7_CHICK Computationally mapped isoform of Caspase recruitment domain-containing protein 10 OS=Gallus gallus OX=9031 GN=CARD10 PE=4 SV=1 CANONICAL=A0A8V0YGT7-1" }, "locus": { "chromosome": "1", "start_pos": 51291943, "end_pos": 51272714, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034164.1", "url": "https://www.ensembl.org/id/ENSGALT00010034164.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020070.1", "url": "https://www.ensembl.org/id/ENSGALP00010020070.1" } ] } }, { "isoform_ac": "A0A8V0YGT7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGT7/entry#A0A8V0YGT7-1", "sequence": { "sequence": "MEQLSTGGGRRCWRLQCWGNDRRAAWPQGEEDVKEDAGICVAPAVCGGQDAKSRRTSPTQLSPCLPTPHCCISPSISPCNALCLLAVSPGHLGASASEPWALGCPPGRTCVFALPWPCLLTRGPSYLPGVNAWEGKTHLPPWRLPPLAAAFGGTGEDARTVAALLPAYPQPRGSCGSARPREWGTHGSVRSDRPVLELPLPGQCFSICGGNQGFLGLETTELGFVTQTMNHKARCTEEKLLVNHILPEINFSPEQQLEETDGPRAKQNPSPAPPGEQRSRGGCPRPAALENASLQACSLSEQEEEEDALWEKIESARHQLTRSLNPAKLTPYLRQCRVIDEQDEEEVLNSCRFPCKSNQTGYLMDILRRRGKRGYEAFLESLEFYYPEHYTRLTGREPAQRCSMILDEEGPEGLMQFLLVEVKKMRAQRKEHLLKEHQLQAKNQTLEQEQARLEQRLQELLKVQERCQRLREEWDSNSVELLRLKDENYMMAMRYAQLCEEKNMAVLRSRDLQLVVDQLKCKVTSLEEECSLLRKQASTMPQRETEERGHPDAVSELWAENQRLTASLQELQGMLQTPGEVPVPGSEQILLDILEHDWKEAQDDRQDLCQKLNSLQSELQWAEELRDKYLQEVEDLQLKYRTLQKDCDLYKHRMNTVLLQLEEIEKERDQAIQSRDGVQLQYSQSLIEKDQYRKRVRALEEERDELLSKLSRVEGLNSTLEAQLQRCRGNRSLGKMCSSSYSLCSNLSSTWSLVDKPSDLTSGLTDPLGVSPIIFPEDSAIHSMEGTPDSEKDINRLSTFPFPPCIGSILRRQREDRCMPYKSLSCGSFSSMEDTAGNSFVSIPPGAFSSSSSSIYTRVKSETCLSMLTSHQEISRRSLVVQLTSMGHPSSLSPREKRLGADISILGGNRTGIYVQWVKPGSQVESTGLREGCRLIKLRVPSLKEEVLSLENCTREVAYLSLLHWDEPSSLVFQLDLQGYQPLREALEEGKKFSGDSFYIRTNLSLLEPSDPYALCVKCREILHVTDTMYKGRLEWYCSRVDPLTMRDLDKGTVPNYSRAHQLLKIQEKVHIPGQQRSHRNNLKKRALDQLRLVKSKQQKSPEQPCQQLWLDPCSDPERSLKPYSLVHPVVVKTPRPVVLSPSCIAPRLIRNLLDLPTSRLDFHVCPAEKLTEGNPSAAHVQEPPVSRNAPQERRESSRVCMIREAMEKNKHCLLELGVQSVRDLIKREIYPIVIHVEVTEKNVRGLRSLLGQPGQRDAEVLKACRGAERALHALPCSWARVEPHAWSHAEELPKVVRGCIFQEQNRPLWVEDGDD", "length": 1316, "header": "tr|A0A8V0YGT7-1|A0A8V0YGT7_CHICK Isoform 1 of Caspase recruitment domain-containing protein 10 OS=Gallus gallus OX=9031 GN=CARD10 PE=4 SV=1 CANONICAL=A0A8V0YGT7-1" }, "locus": { "chromosome": "1", "start_pos": 51291943, "end_pos": 51264198, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034191.1", "url": "https://www.ensembl.org/id/ENSGALT00010034191.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020085.1", "url": "https://www.ensembl.org/id/ENSGALP00010020085.1" } ] } }, { "isoform_ac": "A0A8V0YMY9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGT7/entry#A0A8V0YMY9-1", "sequence": { "sequence": "MLLPGAFQGRVEISTEACERRLELGMPFHASGQAGNQGFLGLETTELGFVTQTMNHKARCTEEKLLVNHILPEINFSPEQQLEETDGPRAKQNPSPAPPALENASLQACSLSEQEEEEDALWEKIESARHQLTRSLNPAKLTPYLRQCRVIDEQDEEEVLNSCRFPCKSNQTGYLMDILRRRGKRGYEAFLESLEFYYPEHYTRLTGREPAQRCSMILDEEGPEGLMQFLLVEVKKMRAQRKEHLLKEHQLQAKNQTLEQEQARLEQRLQELLKVQERCQRLREEWDSNSVELLRLKDENYMMAMRYAQLCEEKNMAVLRSRDLQLVVDQLKCKVTSLEEECSLLRKQASTMPQRETEERGHPDAVSELWAENQRLTASLQELQGMLQTPGEVPVPGSEQILLDILEHDWKEAQDDRQDLCQKLNSLQSELQWAEELRDKYLQEVEDLQLKYRTLQKDCDLYKHRMNTVLLQLEEIEKERDQAIQSRDGVQLQYSQSLIEKDQYRKRVRALEEERDELLSKLSRVEGLNSTLEAQLQRCRGNRSLGKMCSSSYSLCSNLSSTWSLVDKPSDLTSGLTDPLGVSPIIFPEDSAIHSMEGTPDSEKDINRLSTFPFPPCIGSILRRQREDRCMPYKSLSCGSFSSMEDTAGNSFVSIPPGAFSSSSSSIYTRVKSETCLSMLTSHQEISRRSLVVQLTSMGHPSSLSPREKRLGADISILGGNRTGIYVQWVKPGSQVESTGLREGCRLIKLRVPSLKEEVLSLENCTREVAYLSLLHWDEPSSLVFQLDLQGYQPLREALEEGKKFSGDSFYIRTNLSLLEPSDPYALCVKCREILHVTDTMYKGRLEWYCSRVDPLTMRDLDKGTVPNYSRAHQLLKIQEKVHIPGQQRSHRNNLKKRALDQLRLVKSKQQKSPEQPCQQLWLDPCSDPERSLKPYSLVHPVVVKTPRPVVLSPSCIAPRLIRNLLDLPTSRLDFHVCPAEKLTEGNPSAAHVQEPPVSRNAPQERRESSRVCMIREAMEKNKHCLLELGVQSVRDLIKREIYPIVIHVEVTEKNVRGLRSLLGQPGQRDAEVLKACRGAERALHALPCSWARVEPHAWSHAEELPKVVRGCIFQEQNRPLWVEDGDD", "length": 1128, "header": "tr|A0A8V0YMY9-1|A0A8V0YMY9_CHICK Computationally mapped isoform of Caspase recruitment domain-containing protein 10 OS=Gallus gallus OX=9031 GN=CARD10 PE=4 SV=1 CANONICAL=A0A8V0YGT7-1" }, "locus": { "chromosome": "1", "start_pos": 51291943, "end_pos": 51271576, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034174.1", "url": "https://www.ensembl.org/id/ENSGALT00010034174.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020074.1", "url": "https://www.ensembl.org/id/ENSGALP00010020074.1" } ] } }, { "isoform_ac": "A0A8V0YUZ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGT7/entry#A0A8V0YUZ7-1", "sequence": { "sequence": "MLSLGVHQSPGGEEKLLVNHILPEINFSPEQQLEETDGPRAKQNPSPAPPALENASLQACSLSEQEEEEDALWEKIESARHQLTRSLNPAKLTPYLRQCRVIDEQDEEEVLNSCRFPCKSNQTGYLMDILRRRGKRGYEAFLESLEFYYPEHYTRLTGREPAQRCSMILDEEGPEGLMQFLLVEVKKMRAQRKEHLLKEHQLQAKNQTLEQEQARLEQRLQELLKVQERCQRLREEWDSNSVELLRLKDENYMMAMRYAQLCEEKNMAVLRSRDLQLVVDQLKCKVTSLEEECSLLRKQASTMPQRETEERGHPDAVSELWAENQRLTASLQELQGMLQTPGEVPVPGSEQILLDILEHDWKEAQDDRQDLCQKLNSLQSELQWAEELRDKYLQEVEDLQLKYRTLQKDCDLYKHRMNTVLLQLEEIEKERDQAIQSRDGVQLQYSQSLIEKDQYRKRVRALEEERDELLSKLSRVEGLNSTLEAQLQRCRGNRSLGKMCSSSYSLCSNLSSTWSLVDKPSDLTSGLTDPLGVSPIIFPEDSAIHSMEGTPDSEKDINRLSTFPFPPCIGSILRRQREDRCMPYKSLSCGSFSSMEDTAGNSFVSIPPGAFSSSSSSIYTRVKSETCLSMLTSHQEISRRSLVVQLTSMGHPSSLSPREKRLGADISILGGNRTGIYVQWVKPGSQVESTGLREGCRLIKLRVPSLKEEVLSLENCTREVAYLSLLHWDEPSSLVFQLDLQGYQPLREALEEGKKFSGDSFYIRTNLSLLEPSDPYALCVKCREILHVTDTMYKGRLEWYCSRVDPLTMRDLDKGTVPNYSRAHQLLKIQEKVHIPGQQRSHRNNLKKRALDQLRLVKSKQQKSPEQPCQQLWLDPCSDPERSLKPYSLVHPVVVKTPRPVVLSPSCIAPRLIRNLLDLPTSRLDFHVCPAEKLTEGNPSAAHVQEPPVSRNAPQERRESSRVCMIREAMEKNKHCLLELGVQSVRDLIKREIYPIVIHVEVTEKNVRGLR", "length": 1011, "header": "tr|A0A8V0YUZ7-1|A0A8V0YUZ7_CHICK Computationally mapped isoform of Caspase recruitment domain family member 10 OS=Gallus gallus OX=9031 GN=CARD10 PE=4 SV=1 CANONICAL=A0A8V0YGT7-1" }, "locus": { "chromosome": "1", "start_pos": 51291184, "end_pos": 51269760, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034185.1", "url": "https://www.ensembl.org/id/ENSGALT00010034185.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020081.1", "url": "https://www.ensembl.org/id/ENSGALP00010020081.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "regulation of apoptotic process", "id": "GO:0042981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042981", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGT7", "url": 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"sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YGT1-1", "uniprot_ac": "A0A8V0YGT1", "uniprot_id": "A0A8V0YGT1_CHICK", "mass": { "chemical_mass": 36322.0, "monoisotopic_mass": 36322.0 }, "refseq": { "ac": "XP_046794805", "name": "protein Tob2 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046794805" }, "gene_names": [ { "name": "TOB2", "type": "recommended", "evidence": [ { "id": "A0A8V0YGT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGT1" } ] }, { "name": "TOB2", "type": "synonym", "evidence": [ { "id": "XP_046794805", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046794805" } ] } ], "protein_names": [ { "name": "Transducer of ERBB2, 2", "type": "synonym", "evidence": [ { "id": "A0A8V0YGT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGT1/entry#names_and_taxonomy" } ] }, { "name": "protein Tob2 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_046794805", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046794805" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_046794805", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046794805" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGT1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGT1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TOB2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGT1", "locus": { "chromosome": "1", "start_pos": 49692686, "end_pos": 49676165, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012747", "url": "https://www.ensembl.org/id/ENSGALG00010012747" } ] } } ], "crossref": [ { "id": "417992", "url": "https://www.ncbi.nlm.nih.gov/gene/417992", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009818", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009818", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015676", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015676", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036054", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036054", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "NGGISYM", "url": "https://omabrowser.org/oma/group/NGGISYM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YGT1", "url": "https://www.orthodb.org/?gene=A0A8V0YGT1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR17537", "url": 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"categories": [ "Protein" ] } ], "sequence": { "sequence": "MHLEIKVALNFIISYLYNKLPRRRADLFGEELERLLKKKYEGHWYPEKPLKGSGYRCVHIGETVDPVVELAAKRSGLAVEDVRANVPEELSVWIDPFEVSYQIGEKGSVKVLYLDDSEGCSAAELDKEIKSSFNPDAQVFVPIGSQDNSLSNSPSPSFGQSPSPTFIPRSAQPITFTTATFAATKFGSTKMKKGGGAGGGGGGAGATQQPRMVRSPTTNLLKHKGLSLSMHSLNFVGNAGSQAPQSQLSPNAKEFVYSGSSPGASSLFFDGVASESQASSIPPASQFNAGTGSTFDVAQVFGGSTNSLFLEKSPFVEGLSYNLNAMQYPSQSFQPVVLAN", "length": 340, "header": "tr|A0A8V0YGT1-1|A0A8V0YGT1_CHICK Isoform 1 of Transducer of ERBB2, 2 OS=Gallus gallus OX=9031 GN=TOB2 PE=3 SV=1 CANONICAL=A0A8V0YGT1-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YGT1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGT1/entry#A0A8V0YGT1-1", "sequence": { "sequence": 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"MQLEIKVALNFIISYLYNKLPRRRADLFGEELERLLKKKYEGHWYPEKPLKGSGFRCVHIGEMVDPVVELAAKRSGLAVEDVRANVPEELSVWIDPFEVSYQIGEKGAVKVLYLDDSEGCGAPELDKEIKSSFNPDAQVFVPIGSQDSSLSNSPSPSFGQSPSPTFIPRSAQPITFTTASFAATKFGSTKMKKGGGAASGGGVASSGAGGQQPPQQPRMARSPTNSLLKHKSLSLSMHSLNFITANPAPQSQLSPNAKEFVYNGGGSPSLFFDAADGQGSGTPGPFGGSGAGTCNSSSFDMAQVFGGGANSLFLEKTPFVEGLSYNLNTMQYPSQQFQPVVLAN", "length": 344 }, "evidence": [ { "id": "A0A8V0YGT1", "url": "https://omabrowser.org/oma/group/A0A8V0YGT1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9JM55-1", "protein_name": "Protein Tob2", "gene_name": "Tob2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MQLEIKVALNFIISYLYNKLPRRRADLFGEELERLLRKKYEGHWYPEKPLKGSGFRCVHIGEVVDPVVELAAKRSGLAVEDVRANVPEELSVWIDPFEVSYQIGEKGVVKVLYLGDSEASGTPELDKEIKSSFNPDAQVFVPIGSQDSSLSSSPSPSFGQSPSPTFIPRSAQPITFTTASFAATKFGSTKMKKGGGASGGVSVGGSGAGGQQPPPQQPRMARSPTKNLLKHKSLSLSMHSLNLIPANPAPQSQLSPNAKEFVYNGGGSPSLFFDGVEGPSTSTTAPFGSGGASTCNSSSFDVSQVFGGGANSLFLEKSPFVEGLSYNLNTMQYPNQPFQPVVLAN", "length": 345 }, "evidence": [ { "id": "A0A8V0YGT1", "url": "https://omabrowser.org/oma/group/A0A8V0YGT1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGT1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGT1" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGT1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGT1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "transcription corepressor activity", "id": "GO:0003714", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003714", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGT1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGT1" } ], "pmid": "" }, { "name": "nuclear vitamin D receptor binding", "id": "GO:0042809", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042809", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGT1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGT1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "regulation of gene expression", "id": "GO:0010468", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010468", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGT1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGT1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YGT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGT1" }, { "id": "PS00960", "database": "PROSITE", "url": "https://prosite.expasy.org/PS00960" }, { "id": "PS01203", "database": "PROSITE", "url": "https://prosite.expasy.org/PS01203" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Anti-proliferative protein", "eco_id": "ECO_0000259", "start_pos": 40, "end_pos": 60, "start_aa": "Tyr", "end_aa": "Ile", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YGV1-1", "uniprot_ac": "A0A8V0YGV1", "uniprot_id": "A0A8V0YGV1_CHICK", "mass": { "chemical_mass": 102893.0, "monoisotopic_mass": 102893.0 }, "refseq": { "ac": "XP_015138397", "name": "DNA repair and recombination protein RAD54B isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015138397" }, "gene_names": [ { "name": "RAD54B", "type": "recommended", "evidence": [ { "id": "A0A8V0YGV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGV1" } ] }, { "name": "RAD54B", "type": "synonym", "evidence": [ { "id": "XP_015138397", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015138397" } ] } ], "protein_names": [ { "name": "DNA repair and recombination protein RAD54B", "type": "recommended", "evidence": [ { "id": "A0A8V0YGV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGV1/entry#names_and_taxonomy" } ] }, { "name": "DNA repair and recombination protein RAD54B isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015138397", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015138397" } ] }, { "name": "RAD54 homolog B", "type": "synonym", "evidence": [ { "id": "A0A8V0YGV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGV1/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052533.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015138397.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015138397", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015138397" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGV1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGV1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RAD54B", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGV1", "locus": { "chromosome": "2", "start_pos": 125656697, "end_pos": 125718505, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012212", "url": "https://www.ensembl.org/id/ENSGALG00010012212" } ] } } ], "crossref": [ { "id": "A0A8V0YGV1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YGV1", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd18066", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18066", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd18793", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18793", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "395449", "url": "https://www.ncbi.nlm.nih.gov/gene/395449", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000330", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000330", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001650", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001650", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014001", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014001", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038718", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038718", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR049730", "url": "https://www.ebi.ac.uk/interpro/entry/IPR049730", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050496", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050496", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "KCQTHEL", "url": "https://omabrowser.org/oma/group/KCQTHEL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YGV1", "url": "https://www.orthodb.org/?gene=A0A8V0YGV1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45629", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45629", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45629:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45629:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00176", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00176", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00271", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00271", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015138397", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015138397", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "13065", "url": "https://www.rhea-db.org/rhea/13065", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YGV1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGV1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YGV1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGV1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRRSAAPSQVLGNVAKKPRFIPPGKSNALCPKIETEETDQDVKLKEIGEKHGNASLFSEMFSENQSENFTQSVESSGKVKSTKAWNSTSKCSKLEMKTQSAPKADAMHLPTSGMAKEAAAQEEPDCLTKYFSVMWCKASKKKHKKWEGDAILITKGKSVILKDMEGKDIGRGTGYKSKELDSLEEGQTLMIGGKEIEVMGVISADDFSSGRCFQAGIATHDTVPTALPQTTMKQFCKPIKSACQPSTKENILLNPQSCKPRHNPNDTNSLVMPRPNASHQCMFNKAGLPVVDVVVDPYIANNLRPHQREGIVFLYECVMGMRVSGRFGAILADEMGLGKTLQCISLVWTLLRQGVYGCKPVLKRALIVTPGSLVKNWKKEFQKWLGSERIKVFTVDQDHKVEEFISSPLYSVMIISYEMLLRSLDQIQAIEFNLLICDEGHRLKNSSIKTTTALTNLSCERRIILTGTPIQNDLQEFYALIEFVNPGVLGSLSTYRKIYEEPIVRSREPSATKEEKDLGEKRAAELTRLTGLFILRRTQEVINKFLPPKKENIIFCQPTALQLELYRKLLSSRVISSCLQGRLENSPHLICIGALKKLCNHPCLLFKALKEKCCDPKSDEHVESSLYEGLTDVFPQDYTSDTFSEIDSGKLQVLVKLLAAIRELSSSERVVLVSNYTQTLNVLQETCKCYGYSYTRLDGNTPVSQRQQIVDSFNSKFSPAFIFLLSSKAGGVGLNLVGASHLILYDIDWNPATDIQAMARVWRDGQKCTVHIYRLLTTGTIEEKIYQRQISKQDLSGAVVDLSKTSEHIHFSVEELRNLFTLHENSSCVTHDLLECDCMGNKDHQNPSSKKPSVSRCCQLRQDQGKHNSKKPLSMSQLMQWKHFSGQHQALPDPFLERIKENVSFIFQNVTNATSPTQ", "length": 918, "header": "tr|A0A8V0YGV1-1|A0A8V0YGV1_CHICK Isoform 1 of DNA repair and recombination protein RAD54B OS=Gallus gallus OX=9031 GN=RAD54B PE=3 SV=1 CANONICAL=A0A8V0YGV1-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YGV1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGV1/entry#A0A8V0YGV1-1", "sequence": { "sequence": "MRRSAAPSQVLGNVAKKPRFIPPGKSNALCPKIETEETDQDVKLKEIGEKHGNASLFSEMFSENQSENFTQSVESSGKVKSTKAWNSTSKCSKLEMKTQSAPKADAMHLPTSGMAKEAAAQEEPDCLTKYFSVMWCKASKKKHKKWEGDAILITKGKSVILKDMEGKDIGRGTGYKSKELDSLEEGQTLMIGGKEIEVMGVISADDFSSGRCFQAGIATHDTVPTALPQTTMKQFCKPIKSACQPSTKENILLNPQSCKPRHNPNDTNSLVMPRPNASHQCMFNKAGLPVVDVVVDPYIANNLRPHQREGIVFLYECVMGMRVSGRFGAILADEMGLGKTLQCISLVWTLLRQGVYGCKPVLKRALIVTPGSLVKNWKKEFQKWLGSERIKVFTVDQDHKVEEFISSPLYSVMIISYEMLLRSLDQIQAIEFNLLICDEGHRLKNSSIKTTTALTNLSCERRIILTGTPIQNDLQEFYALIEFVNPGVLGSLSTYRKIYEEPIVRSREPSATKEEKDLGEKRAAELTRLTGLFILRRTQEVINKFLPPKKENIIFCQPTALQLELYRKLLSSRVISSCLQGRLENSPHLICIGALKKLCNHPCLLFKALKEKCCDPKSDEHVESSLYEGLTDVFPQDYTSDTFSEIDSGKLQVLVKLLAAIRELSSSERVVLVSNYTQTLNVLQETCKCYGYSYTRLDGNTPVSQRQQIVDSFNSKFSPAFIFLLSSKAGGVGLNLVGASHLILYDIDWNPATDIQAMARVWRDGQKCTVHIYRLLTTGTIEEKIYQRQISKQDLSGAVVDLSKTSEHIHFSVEELRNLFTLHENSSCVTHDLLECDCMGNKDHQNPSSKKPSVSRCCQLRQDQGKHNSKKPLSMSQLMQWKHFSGQHQALPDPFLERIKENVSFIFQNVTNATSPTQ", "length": 918, "header": "tr|A0A8V0YGV1-1|A0A8V0YGV1_CHICK Isoform 1 of DNA repair and recombination protein RAD54B OS=Gallus gallus OX=9031 GN=RAD54B PE=3 SV=1 CANONICAL=A0A8V0YGV1-1" }, "locus": { "chromosome": "2", "start_pos": 125716370, "end_pos": 125657679, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029281.1", "url": "https://www.ensembl.org/id/ENSGALT00010029281.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016996.1", "url": "https://www.ensembl.org/id/ENSGALP00010016996.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "Q6PFE3-1", "protein_name": "DNA repair and recombination protein RAD54B", "gene_name": "Rad54b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRRSAAPSQVQGKSFKKTRFIPPGRSNADVSKEITKMSPDPKLFQGAEQSQNDPGVCSSNPCPSEGIPREVGDGTRVDPLPPVHSASKEITESKAQEEEASSLLKYFSVVWCKASKKKHKKWEGDAILIVRGRSFTLKDLEGKDIGRGIGYKFKDLENVEEGQTLIIGGKEIEILGTISSDDFNSGKCFQHGSGSPAVPSSQAARKCFSNPFKSVCQSTQAQGKRWNDCRPRHNPCTPNALVMPRPDENHQRMFNRHCSPIVDVVIDPHLVHHLRPHQKDGIIFLYECVMGMRAVGKCGAILADEMGLGKTLQCISLIWTLQCQGPYGGKPVIKKTLIVTPGSLVNNWRKEFQKWLGSERIKIFTVDQDHKVEEFINSTFHSVLIISYEMLLRSLDQIKTIPFGLLICDEGHRLKNSSIKTTTALSSLSCEKTVILTGTPVQNDLQEFFALVDFVNPGILGSLSSYRKIYEEPIIISREPSSSKEERELGERRATELTRLTGRFILRRTQEVINKYLPPKIENVVFCRPGALQIELYRKLLRSQSVRFCLQGLLENSAHLICIGALKKLCNHPCLLFSSVKGKEFSSSCEENEERNLCQGLLSVFPAGYNPLQFSEEESGKLQVLVKLLAVIHELRPTEKVILVSNYRQTLNVLEEVCKRHGYACARLDGQTPVSQRQHIVDSFNSKYSTDFIFLLSSKAGGVGLNLIGGSHLILYDIDWNPATDIQAMSRVWRDGQKHPVHIYRLLTTGTIEEKIYQRQISKQGLSGAVVDLTRSSEHIQFSVEELKNLFTLHESSHCVTHDLLDCECTGEKGHTEDASEGPVASRQCQFGPQKSDALRPLSMSQLKQWKHFSGDHLNLPDPFLERIRENVSFFFQNITNQAPAV", "length": 886 }, "evidence": [ { "id": "A0A8V0YGV1", "url": "https://omabrowser.org/oma/group/A0A8V0YGV1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9Y620-1", "protein_name": "DNA repair and recombination protein RAD54B", "gene_name": "RAD54B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRRSAAPSQLQGNSFKKPKFIPPGRSNPGLNEEITKLNPDIKLFEGVAINNTFLPSQNDLRICSLNLPSEESTREINNRDNCSGKYCFEAPTLATLDPPHTVHSAPKEVAVSKEQEEKSDSLVKYFSVVWCKPSKKKHKKWEGDAVLIVKGKSFILKNLEGKDIGRGIGYKFKELEKIEEGQTLMICGKEIEVMGVISPDDFSSGRCFQLGGGSTAISHSSQVARKCFSNPFKSVCKPSSKENRQNDFQNCKPRHDPYTPNSLVMPRPDKNHQWVFNKNCFPLVDVVIDPYLVYHLRPHQKEGIIFLYECVMGMRMNGRCGAILADEMGLGKTLQCISLIWTLQCQGPYGGKPVIKKTLIVTPGSLVNNWKKEFQKWLGSERIKIFTVDQDHKVEEFIKSIFYSVLIISYEMLLRSLDQIKNIKFDLLICDEGHRLKNSAIKTTTALISLSCEKRIILTGTPIQNDLQEFFALIDFVNPGILGSLSSYRKIYEEPIILSREPSASEEEKELGERRAAELTCLTGLFILRRTQEIINKYLPPKIENVVFCRPGALQIELYRKLLNSQVVRFCLQGLLENSPHLICIGALKKLCNHPCLLFNSIKEKECSSTCDKNEEKSLYKGLLSVFPADYNPLLFTEKESGKLQVLSKLLAVIHELRPTEKVVLVSNYTQTLNILQEVCKRHGYAYTRLDGQTPISQRQQIVDGFNSQHSSFFIFLLSSKAGGVGLNLIGGSHLILYDIDWNPATDIQAMSRVWRDGQKYPVHIYRLLTTGTIEEKIYQRQISKQGLCGAVVDLTKTSEHIQFSVEELKNLFTLHESSDCVTHDLLDCECTGEEVHTGDSLEKFIVSRDCQLGPHHQKSNSLKPLSMSQLKQWKHFSGDHLNLTDPFLERITENVSFIFQNITTQATGT", "length": 910 }, "evidence": [ { "id": "A0A8V0YGV1", "url": "https://omabrowser.org/oma/group/A0A8V0YGV1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 6, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGV1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGV1" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGV1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGV1" } ], "pmid": "" }, { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGV1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGV1" } ], "pmid": "" }, { "name": "protein-macromolecule adaptor activity", "id": "GO:0030674", 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"evidence": [ { "id": "A0A1D5PIN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PIN7" } ] } ] }, { "uniprot_ac": "A0A1D5PRR9", "gene_name": "FANCM", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5PRR9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRR9" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A1D5PRR9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRR9" } ] } ] }, { "uniprot_ac": "A0A1D5PS27", "gene_name": "ENTPD2", "activity": [ { "ec_number": "3.6.1.5", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + 2 H2O = a 2'-deoxyribonucleoside 5'-phosphate + 2 phosphate + 2 H(+).", "evidence": [ { "id": "A0A1D5PS27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PS27" } ] }, { "ec_number": "3.6.1.5", "activity": "", "evidence": [ { "id": "A0A1D5PS27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PS27" } ] } ] }, { "uniprot_ac": "A0A1D5PVS9", "gene_name": "ENTPD3", "activity": [ { "ec_number": "3.6.1.5", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + 2 H2O = a 2'-deoxyribonucleoside 5'-phosphate + 2 phosphate + 2 H(+).", "evidence": [ { "id": "A0A1D5PVS9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PVS9" } ] }, { "ec_number": "3.6.1.5", "activity": "", "evidence": [ { "id": "A0A1D5PVS9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PVS9" } ] } ] }, { "uniprot_ac": "A0A3S5ZPN3", "gene_name": "DDX5", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A3S5ZPN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPN3" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A3S5ZPN3", "database": "UniProtKB", "url": 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"activity": "", "evidence": [ { "id": "A0A8V0XGV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XGV3" } ] } ] }, { "uniprot_ac": "A0A8V0XHD1", "gene_name": "AQR", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XHD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XHD1" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0XHD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XHD1" } ] } ] }, { "uniprot_ac": "A0A8V0XI26", "gene_name": "DDX1", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XI26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XI26" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0XI26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XI26" } ] } ] }, { "uniprot_ac": "A0A8V0XJV9", "gene_name": "SPATA5", "activity": [ { "ec_number": "3.6.4.6", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XJV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XJV9" } ] }, { "ec_number": "3.6.4.6", "activity": "", "evidence": [ { "id": "A0A8V0XJV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XJV9" } ] }, { "ec_number": "3.6.4.10", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XJV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XJV9" } ] }, { "ec_number": "3.6.4.10", "activity": "", "evidence": [ { "id": "A0A8V0XJV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XJV9" } ] } ] }, { "uniprot_ac": "A0A8V0XLC7", "gene_name": "MCM4", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XLC7", "database": 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} ] }, { "uniprot_ac": "A0A8V0ZTR5", "gene_name": "LOC423693", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0ZTR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTR5" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0ZTR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTR5" } ] } ] }, { "uniprot_ac": "A0A8V0ZU49", "gene_name": "DNA2", "activity": [ { "ec_number": "3.1.-.-", "activity": "", "evidence": [ { "id": "A0A8V0ZU49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU49" } ] }, { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0ZU49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU49" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "A0A8V0ZU49", "database": "UniProtKB", "url": 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"ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0ZUT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUT3" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0ZUT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUT3" } ] } ] }, { "uniprot_ac": "A0A8V0ZVY2", "gene_name": "RTEL1", "activity": [ { "ec_number": "5.6.2.-", "activity": "", "evidence": [ { "id": "A0A8V0ZVY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVY2" } ] } ] }, { "uniprot_ac": "A0A8V0ZWH7", "gene_name": "DHX35", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0ZWH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWH7" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0ZWH7", "database": "UniProtKB", "url": 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"ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V1A3M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3M1" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V1A3M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3M1" } ] } ] }, { "uniprot_ac": "A0A8V1A4V3", "gene_name": "POLQ", "activity": [ { "ec_number": "2.7.7.7", "activity": "DNA(n) + a 2'-deoxyribonucleoside 5'-triphosphate = DNA(n+1) + diphosphate.", "evidence": [ { "id": "A0A8V1A4V3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4V3" } ] }, { "ec_number": "2.7.7.49", "activity": "DNA(n) + a 2'-deoxyribonucleoside 5'-triphosphate = DNA(n+1) + diphosphate.", "evidence": [ { "id": "A0A8V1A4V3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4V3" } ] }, { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": 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"url": "https://www.uniprot.org/uniprotkb/F1NHI3" } ] } ] }, { "uniprot_ac": "F1NN44", "gene_name": "ALPL", "activity": [ { "ec_number": "3.1.3.1", "activity": "a phosphate monoester + H2O = an alcohol + phosphate.", "evidence": [ { "id": "F1NN44", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NN44" } ] }, { "ec_number": "3.1.3.1", "activity": "", "evidence": [ { "id": "F1NN44", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NN44" } ] } ] }, { "uniprot_ac": "F1NQJ3", "gene_name": "PMS2", "activity": [ { "ec_number": "3.1.-.-", "activity": "", "evidence": [ { "id": "F1NQJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NQJ3" } ] } ] }, { "uniprot_ac": "F1NTD6", "gene_name": "ascc3", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1NTD6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NTD6" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "F1NTD6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NTD6" } ] } ] }, { "uniprot_ac": "F1NZ23", "gene_name": "ERCC3", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1NZ23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NZ23" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "F1NZ23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NZ23" } ] } ] }, { "uniprot_ac": "F1P5C0", "gene_name": "DDX20", "activity": [ { "ec_number": "3.6.1.15", "activity": "a ribonucleoside 5'-triphosphate + H2O = a ribonucleoside 5'-diphosphate + phosphate + H(+).", "evidence": [ { "id": "F1P5C0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P5C0" } ] }, { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1P5C0", "database": "UniProtKB", "url": 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"database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y8F7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y8F7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YC55", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC55", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YC55-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC55-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YGV4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGV4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YGV4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGV4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "RGRGRGPPRRRPRPCERRRRNRECPTRWLLGGEATRCLALLRPPPLRRAGRCPAAAPPVHGTYLELPAGCGAPRPEQEQEQEAAGRAEAPRSRAVTGWRGETGGREEEKESGGTARVDSGSGSRHPGPARPGGHAWVQSSGPGGRCTRRRRTPPTPRSSSGACLTTPPTPACASTSRCSATSRRRWSSPTGRRVTMADRAAAERACKDPNPIIDGRKANVNLAYLGAKPRIMQPGFAFGVQQLHPALIQRPFGIPAHYVYPQAFVQPGVVIPHVQPAAAAASTTPYIDYTGAAYAQYSAAAAAYEQYPYAASPAAAAGYVAAGGYGYAVQQPITAAAPGTAAAAAAAFGQYQPQQLQTDRMQ", "length": 362, "header": "tr|A0A8V0YGV4-1|A0A8V0YGV4_CHICK Isoform 1 of RNA binding motif protein 24 OS=Gallus gallus OX=9031 GN=RBM24 PE=4 SV=1 CANONICAL=A0A8V0YGV4-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Y3P6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGV4/entry#A0A8V0Y3P6-1", "sequence": { "sequence": "MHTTQKDTTYTKIFVGGLPYHTTDSSLRKYFEVFGDIEEAVVITDRQTGKSRGYGFVTMADRAAAERACKDPNPIIDGRKANVNLAYLGAKPRIMQPGFCAARSGNSPRPTRSSRCFHYALHRLHRSCLRPVLGRRGRLRAIPVRRLSGRRCRLRGGGGLRLRGAAAHHRSGTGDGGCGGCGFWPVPTPTAADRSYAIADGLPREARSFSSSFFGLPV", "length": 218, "header": "tr|A0A8V0Y3P6-1|A0A8V0Y3P6_CHICK Computationally mapped isoform of RNA binding motif protein 24 OS=Gallus gallus OX=9031 GN=RBM24 PE=4 SV=1 CANONICAL=A0A8V0YGV4-1" }, "locus": { "chromosome": "2", "start_pos": 61662267, "end_pos": 61653724, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026716.1", "url": "https://www.ensembl.org/id/ENSGALT00010026716.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015239.1", "url": "https://www.ensembl.org/id/ENSGALP00010015239.1" } ] } }, { "isoform_ac": "A0A8V0Y8F7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGV4/entry#A0A8V0Y8F7-1", "sequence": { "sequence": "MHTTQKDTTYTKIFVGGLPYHTTDSSLRKYFEVFGDIEEAVVITDRQTGKSRGYGFVTMADRAAAERACKDPNPIIDGRKANVNLAYLGAKPRIMQPGFAFGVQQLHPALIQRPFGNKQAGTKQDSSGLIIKQDPSSLCLSTGFCAARSGNSPRPTRSSRCFHYALHRLHRSCLRPVLGRRGRLRAIPVRRLSGRRCRLRGGGGLRLRGAAAHHRSGTGDGGCGGCGFWPVPTPTAADRSYAIADGLPREARSFSSSFFGLPV", "length": 263, "header": "tr|A0A8V0Y8F7-1|A0A8V0Y8F7_CHICK Computationally mapped isoform of RNA binding motif protein 24 OS=Gallus gallus OX=9031 GN=RBM24 PE=4 SV=1 CANONICAL=A0A8V0YGV4-1" }, "locus": { "chromosome": "2", "start_pos": 61662267, "end_pos": 61653724, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026711.1", "url": "https://www.ensembl.org/id/ENSGALT00010026711.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015238.1", "url": "https://www.ensembl.org/id/ENSGALP00010015238.1" } ] } }, { "isoform_ac": "A0A8V0YC55-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGV4/entry#A0A8V0YC55-1", "sequence": { "sequence": "MHTTQKDTTYTKIFVGGLPYHTTDSSLRKYFEVFGDIEEAVVITDRQTGKSRGYGFVTMADRAAAERACKDPNPIIDGRKANVNLAYLGAKPRIMQPGFAFGVQQLHPALIQRPFGDRLQIPAHYVYPQAFVQPGVVIPHVQPAAAAASTTPYIDYTGAAYAQYSAAAAAYEQYPYAASPAAAAGYVAAGGYGYAVQQPITAAAPGTAAAAAAAFGQYQPQQLQTDRMQ", "length": 229, "header": "tr|A0A8V0YC55-1|A0A8V0YC55_CHICK Computationally mapped isoform of RNA binding motif protein 24 OS=Gallus gallus OX=9031 GN=RBM24 PE=4 SV=1 CANONICAL=A0A8V0YGV4-1" }, "locus": { "chromosome": "2", "start_pos": 61662205, "end_pos": 61653724, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026702.1", "url": "https://www.ensembl.org/id/ENSGALT00010026702.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015232.1", "url": "https://www.ensembl.org/id/ENSGALP00010015232.1" } ] } }, { "isoform_ac": "A0A8V0YGV4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGV4/entry#A0A8V0YGV4-1", "sequence": { "sequence": "RGRGRGPPRRRPRPCERRRRNRECPTRWLLGGEATRCLALLRPPPLRRAGRCPAAAPPVHGTYLELPAGCGAPRPEQEQEQEAAGRAEAPRSRAVTGWRGETGGREEEKESGGTARVDSGSGSRHPGPARPGGHAWVQSSGPGGRCTRRRRTPPTPRSSSGACLTTPPTPACASTSRCSATSRRRWSSPTGRRVTMADRAAAERACKDPNPIIDGRKANVNLAYLGAKPRIMQPGFAFGVQQLHPALIQRPFGIPAHYVYPQAFVQPGVVIPHVQPAAAAASTTPYIDYTGAAYAQYSAAAAAYEQYPYAASPAAAAGYVAAGGYGYAVQQPITAAAPGTAAAAAAAFGQYQPQQLQTDRMQ", "length": 362, "header": "tr|A0A8V0YGV4-1|A0A8V0YGV4_CHICK Isoform 1 of RNA binding motif protein 24 OS=Gallus gallus OX=9031 GN=RBM24 PE=4 SV=1 CANONICAL=A0A8V0YGV4-1" }, "locus": { "chromosome": "2", "start_pos": 61662205, "end_pos": 61653290, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026720.1", "url": "https://www.ensembl.org/id/ENSGALT00010026720.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015240.1", "url": "https://www.ensembl.org/id/ENSGALP00010015240.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 169, "start_aa": "Thr", "end_pos": 169, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr169", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGV4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGV4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGV4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGV4" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGV4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGV4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "mRNA processing", "id": "GO:0006397", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006397", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGV4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGV4" } ], "pmid": "" }, { "name": "regulation of translation", "id": "GO:0006417", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006417", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGV4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGV4" } ], "pmid": "" }, { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGV4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGV4" } ], "pmid": "" }, { "name": "RNA splicing", "id": "GO:0008380", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008380", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGV4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGV4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 169 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YGW2-1", "uniprot_ac": "A0A8V0YGW2", "uniprot_id": "A0A8V0YGW2_CHICK", "mass": { "chemical_mass": 50575.0, "monoisotopic_mass": 50575.0 }, "refseq": {}, "gene_names": [ { "name": "STK32B", "type": "recommended", "evidence": [ { "id": "A0A8V0YGW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGW2" } ] } ], "protein_names": [ { "name": "non-specific serine/threonine protein kinase", "type": "recommended", "evidence": [ { "id": "A0A8V0YGW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGW2/entry#names_and_taxonomy" } ] }, { "name": "2.7.11.1", "type": "synonym", "evidence": [ { "id": "A0A8V0YGW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGW2/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGW2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGW2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "STK32B", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGW2", "locus": { "chromosome": "4", "start_pos": 78582434, "end_pos": 78394704, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010011187", "url": "https://www.ensembl.org/id/ENSGALG00010011187" } ] } } ], "crossref": [ { "id": "A0A8V0YGW2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YGW2", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd05578", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05578", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000719", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000719", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008271", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008271", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011009", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011009", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017441", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017441", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:422850", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422850", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YC70", "url": "https://www.orthodb.org/?gene=A0A8V0YC70", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YC75", "url": "https://www.orthodb.org/?gene=A0A8V0YC75", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YGW2", "url": "https://www.orthodb.org/?gene=A0A8V0YGW2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24355", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24355", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24355:SF33", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24355:SF33", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00069", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00069", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "17989", "url": "https://www.rhea-db.org/rhea/17989", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "46608", "url": "https://www.rhea-db.org/rhea/46608", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YC70", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC70", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YC70-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC70-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YC75", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC75", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YC75-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC75-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YGW2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGW2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YGW2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGW2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRSRLWTNMGGSHSHRAPVFDENEDVNFDHFQILRAIGKGSFGKVCIVQKRDTKKMYAMKYMNKQKCIERDEVRNVFRELQIMQGLEHPFLVNLWNLNTAVGKTSSHPDSRFKYSFQDEEDMFMVVDLLLGGDLRYHLQQNVHFNEGTVKLYICELALSLDYLQRYHIIHRDIKPDNILLDEHGHVHITDFNIATIVKGSEKASSMAGTKPYMAPEVFQAFMDGGPGYSYPVDWWSLGITAYELLRGWRPYEIHSATPIDEILNMFKIERVHYSSTWCKGMIALLKKLLTKDPDCRLSSLADIQSSPYLVDVNWDAVLEKAVTPGFVPNKGRLNCDPTFELEEMILESKPLHKKKKRLAKNKSKDGTKESCPLNVHLQQCLETVRKEFIIFNREKLRRQQDQSGQTSSTDSRASLQSHGKLQDGRNNNLLGHGCTRGCSS", "length": 440, "header": "tr|A0A8V0YGW2-1|A0A8V0YGW2_CHICK Isoform 1 of non-specific serine/threonine protein kinase OS=Gallus gallus OX=9031 GN=STK32B PE=3 SV=1 CANONICAL=A0A8V0YGW2-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YC70-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGW2/entry#A0A8V0YC70-1", "sequence": { "sequence": "MRSRLWTNMGGSHSHRAPVFDENEDVNFDHFQILRAIGKGSFGKVCIVQKRDTKKMYAMKYMNKQKCIERDEVRNVFRELQIMQGLEHPFLVNLWYSFQDEEDMFMVVDLLLGGDLRYHLQQNVHFNEGTVKLYICELALSLDYLQRYHIIHRDIKPDNILLDEHGHVHITDFNIATIVKGSEKASSMAGTKPYMAPEVFQAFMDGGPGYSYPVDWWSLGITAYELLRGWRPYEIHSATPIDEILNMFKIERVHYSSTWCKGMIALLKKLLTKDPDCRLSSLADIQSSPYLVDVNWDAVLEKAVTPGFVPNKGRLNCDPTFELEEMILESKPLHKKKKRLAKNKSKDGTKESCPLTKKAAGSKRADFQHGQQSILAEPWEASRWT", "length": 385, "header": "tr|A0A8V0YC70-1|A0A8V0YC70_CHICK Computationally mapped isoform of Serine/threonine-protein kinase 32B OS=Gallus gallus OX=9031 GN=STK32B PE=3 SV=1 CANONICAL=A0A8V0YGW2-1" }, "locus": { "chromosome": "4", "start_pos": 78581107, "end_pos": 78434943, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026735.1", "url": "https://www.ensembl.org/id/ENSGALT00010026735.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015247.1", "url": "https://www.ensembl.org/id/ENSGALP00010015247.1" } ] } }, { "isoform_ac": "A0A8V0YC75-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGW2/entry#A0A8V0YC75-1", "sequence": { "sequence": "MADVIRRKAGWCKFNFDHFQILRAIGKGSFGKVCIVQKRDTKKMYAMKYMNKQKCIERDEVRNVFRELQIMQGLEHPFLVNLWYSFQDEEDMFMVVDLLLGGDLRYHLQQNVHFNEGTVKLYICELALSLDYLQRYHIIHRDIKPDNILLDEHGHVHITDFNIATIVKGSEKASSMAGTKPYMAPEVFQAFMDGGPGYSYPVDWWSLGITAYELLRGWRPYEIHSATPIDEILNMFKIERVHYSSTWCKGMIALLKKLLTKDPDCRLSSLADIQSSPYLVDVNWDAVLEKAVTPGFVPNKGRLNCDPTFELEEMILESKPLHKKKKRLAKNKSKDGTKESCPLNVHLQQCLETVRKEFIIFNREKLRRQQDQSGQTSSTDSRASLQSHGKLQDGRNNNLLGHGCTRGCSS", "length": 410, "header": "tr|A0A8V0YC75-1|A0A8V0YC75_CHICK Computationally mapped isoform of Serine/threonine-protein kinase 32B OS=Gallus gallus OX=9031 GN=STK32B PE=3 SV=1 CANONICAL=A0A8V0YGW2-1" }, "locus": { "chromosome": "4", "start_pos": 78581153, "end_pos": 78406916, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026744.1", "url": "https://www.ensembl.org/id/ENSGALT00010026744.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015252.1", "url": "https://www.ensembl.org/id/ENSGALP00010015252.1" } ] } }, { "isoform_ac": "A0A8V0YGW2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGW2/entry#A0A8V0YGW2-1", "sequence": { "sequence": "MRSRLWTNMGGSHSHRAPVFDENEDVNFDHFQILRAIGKGSFGKVCIVQKRDTKKMYAMKYMNKQKCIERDEVRNVFRELQIMQGLEHPFLVNLWNLNTAVGKTSSHPDSRFKYSFQDEEDMFMVVDLLLGGDLRYHLQQNVHFNEGTVKLYICELALSLDYLQRYHIIHRDIKPDNILLDEHGHVHITDFNIATIVKGSEKASSMAGTKPYMAPEVFQAFMDGGPGYSYPVDWWSLGITAYELLRGWRPYEIHSATPIDEILNMFKIERVHYSSTWCKGMIALLKKLLTKDPDCRLSSLADIQSSPYLVDVNWDAVLEKAVTPGFVPNKGRLNCDPTFELEEMILESKPLHKKKKRLAKNKSKDGTKESCPLNVHLQQCLETVRKEFIIFNREKLRRQQDQSGQTSSTDSRASLQSHGKLQDGRNNNLLGHGCTRGCSS", "length": 440, "header": "tr|A0A8V0YGW2-1|A0A8V0YGW2_CHICK Isoform 1 of non-specific serine/threonine protein kinase OS=Gallus gallus OX=9031 GN=STK32B PE=3 SV=1 CANONICAL=A0A8V0YGW2-1" }, "locus": { "chromosome": "4", "start_pos": 78581153, "end_pos": 78434943, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026741.1", "url": "https://www.ensembl.org/id/ENSGALT00010026741.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015250.1", "url": "https://www.ensembl.org/id/ENSGALP00010015250.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 323, "start_aa": "Thr", "end_pos": 323, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr323", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:422850", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422850", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGW2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGW2" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGW2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGW2" } ], "pmid": "" }, { "name": "G protein-coupled receptor binding", "id": "GO:0001664", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001664", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGW2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGW2" } ], "pmid": "" }, { "name": "G protein-coupled receptor kinase activity", "id": "GO:0004703", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004703", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGW2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGW2" } ], "pmid": "" }, { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGW2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGW2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor signaling pathway", "id": "GO:0007186", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007186", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGW2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGW2" } ], "pmid": "" }, { "name": "regulation of signal transduction", "id": "GO:0009966", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009966", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGW2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGW2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 361, "end_pos": 363, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "17989", "name": "", "equation": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q6U1I9-1", "A0A8V0XNJ2-1", "A0A8V0ZUL0-1", "A0A8V0ZT63-1", "A0A8V1ACW2-1", "A0A8V0Z1X0-1", "A0A8V0YHN2-1", "A0A8V0YMN5-1", "A0A8V0Z807-1", "A0A8V0Z930-1", "A0A8V0YFR6-1", "A0A1D5P0M9-1", "A0A8V0ZBN6-1", "A0A3Q2U9U9-1", "A0A8V0YXZ5-1", "A0A8V0ZSP4-1", "A0A8V0ZXQ9-1", "A0A8V0ZZV3-1", "A0A8V1ADF0-1", "A0A8V0ZFT3-1", "A0A8V0ZA45-1", "A0A8V0ZB33-1", "A0A8V0ZD70-1", "A0A8V0Z8T4-1", "R4GIN8-1", "A0A8V0ZK64-1", "A0A8V0ZC16-1", "A0A8V0ZWW1-1", "E1BY69-1", "A0A8V0ZDW9-1", "A0A8V0ZKA2-1", "A0A3Q3B2F1-1", "F1P356-1", "A0A8V1AHA8-1", "Q8QFP8-1", "F1P011-1", "A0A8V0YKK3-1", "A0A1D5NWT4-1", "A0A1D5PMQ7-1", "E1BWA3-1", "F1NVF2-1", "A0A1D5PXN4-1", "A0A3Q2TY19-1", "A0A3Q2U592-1", "A0A8V0XCV5-1", "A0A1D5P8A9-1", "A0A1D5PMG2-1", "A0A8V0X1Q7-1", "A0A8V0Y935-1", "A0A8V0YM96-1", "A0A8V0YF83-1", "A0A8V0YJP9-1", "A0A8V1AKW4-1", "A0A8V0ZSB4-1", "F1NBT0-1", "P18652-1", "P21868-1", "P21869-1", "P53666-1", "P79996-1", "Q5F3W3-1", "Q5ZJS0-1", "Q5ZKN1-1", "Q5ZLL1-1", "A0A8V0XCS0-1", "A0A8V0XNK8-1", "A0A8V0XLV6-1", "A0A8V0XDR5-1", "E1BYH2-1", "E1BQN6-1", "A0A8V0XU71-1", "Q5ZJH6-1", "A0A8V0Y3D1-1", "A0A8V0Y7C3-1", "A0A8V0YCY4-1", "A0A8V0YIV6-1", "A0A8V0YK18-1", "A0A8V0YM22-1", "A0A8V0YTN5-1", "A0A8V0YTP2-1", "Q5F3L1-1", "A0A8V0Y3L2-1", "A0A8V0YCY8-1", "A0A8V0Y9Q1-1", "A0A8V0ZD48-1", "A0A8V0ZD60-1", "A0A8V0ZBZ2-1", "A0A8V0Z9J0-1", "A0A8V1ABF3-1", "Q8AYC9-1", "A0A8V0Z927-1", "A0A8V1A2T9-1", "Q5ZKI0-1", "Q7T0B1-1", "P10741-1", "A0A8V0YFH4-1", "E1C848-1", "A0A8V0X8M1-1", "E1BW33-1", "A0A8V0Z283-1", "A0A8V0Z157-1", "A0A3Q2U4X3-1", "A0A8V0XW11-1", "E1BUG0-1", "A0A8V1ABP4-1", "A0A8V1AJA4-1", "A0A8V1AEH4-1", "F1NJH1-1", "A0A8V1AMK5-1", "A0A3Q2TRY2-1", "A0A8V0X3D6-1", "A0A1D5PD64-1", "A0A8V0XQ97-1", "R4GJB8-1", "A0A8V0X5Z8-1", "A0A8V0XG21-1", "A0A8V0XB58-1", "A0A8V0XMX8-1", "A0A8V0XQS0-1", "A0A8V0XW29-1", "A0A8V0Y074-1", "A0A8V0XXB8-1", "A0A8V0XQ14-1", "A0A8V0XMT1-1", "A0A8V0Y457-1", "A0A8V0Y823-1", "A0A8V0Y4L8-1", "A0A8V0XND6-1", "A0A8V0YZ74-1", "A0A8V0YTI1-1", "A0A8V0YLV1-1", "A0A8V0Z2E3-1", "A0A8V0YCV9-1", "A0A8V0YSH3-1", "A0A8V0YYX2-1", "A0A8V0YZY4-1", "Q5ZIU3-1", "A0A8V0YZK0-1", "A0A8V0ZKM9-1", "A0A8V0ZWC7-1", "A0A8V1A1Y7-1", "A0A8V1A069-1", "A0A8V0ZI32-1", "A0A8V0ZH91-1", "E1BQV7-1", "A0A8V0ZRX1-1", "A0A8V0ZUU9-1", "A0A8V1A0Y8-1", "A0A8V1A7E9-1", "A0A8V1A7E0-1", "A0A8V1A3T8-1", "A0A8V1A9S5-1", "A0A8V1A7M0-1", "A0A8V1A675-1", "A0A8V1A1P3-1", "A0A8V1ADT4-1", "E1BWT0-1", "A0A8V1ACF6-1", "A0A8V1ADN9-1", "A0A8V1AM12-1", "A0A8V1A4Q4-1", "Q90891-1", "A0A1D5P517-1", "F1NB57-1", "F1NUX4-1", "A0A8V0ZZE4-1", "P05625-1", "P13863-1", "P67962-1", "Q04982-2", "Q0GGW5-1", "Q6XUX0-1", "Q8QGX4-1", "Q9I9E0-1", "Q9IA88-1", "Q5ZJK4-1", "A0A1D5PTJ8-1", "E1C2I2-1", "F1NCX7-1", "F1NKW3-1", "A0A8V1A0W4-1", "A0A8V1A4J8-1", "A0A8V1ACK0-1", "F1NCY7-1", "A0A8V0X6T4-1", "A0A8V0ZFM2-1", "A0A8V0XUM6-1", "A0A8V0XEA3-1", "A0A8V1AIY7-1", "A0A8V0YHH2-1", "A0A3Q2UI52-1", "A0A8V0ZZK5-1", "A0A8V0ZPX2-1", "A0A8V1ACB5-1", "A0A8V0YDH4-1", "A0A8V1AFS4-1", "A0A8V1AH12-1", "A0A8V0YRC9-1", "A0A8V0ZQT5-1", "A0A8V0ZFP1-1", "E1C764-1", "A0A1D5PUY5-1", "F1P4G3-1", "A0A8V0ZMK1-1", "A0A8V0Y2I5-1", "A0A8V0ZLU3-1", "A0A8V0ZNP7-1", "A0A8V0Z2Z3-1", "A0A8V0YNI5-1", "Q90771-1", "A0A8V0X4P0-1", "A0A8V0X7R2-1", "A0A3Q3A664-1", "A0A8V0YGW2-1", "E1C581-1", "A0A8V1AC40-1", "A0A3Q2TUS7-1", "A0A1D5PA08-1", "A0A8V0XFW1-1", "A0A8V0XAH9-1", "A0A8V1A4A1-1", "A0A8V0ZD40-1", "A0A8V0Z6T1-1", "A0A8V1A4V7-1", "E1C093-1", "A0A8V0YZF2-1", "E1BX69-1", "A0A8V0XI18-1", "A0A8V0Y955-1", "A0A1D5PB73-1", "A0A1D5PV76-1", "A0A1D5PX90-1", "A0A1L1RWI9-1", "A0A3Q2TV19-1", "A0A3Q2UF44-1", "A0A8V0X4Q3-1", "A0A8V0Z124-1", "A0A8V0Z6K4-1", "A0A8V1AE45-1", "A0A8V0YZV9-1", "A0A8V0YYZ3-1", "A0A8V0ZUC6-1", "A0A8V0ZUU8-1", "A0A8V1AG70-1", "F1NA68-1", "F1NLR7-1", "A0A8V0Y6K1-1", "A0A8V0XS42-1", "A0A8V0YRN4-1", "A0A8V0YFP8-1", "A0A8V1A7P9-1", "A0A1D5PRN8-1", "A0A3Q3AAD7-1", "A0A3Q2TWZ8-1", "A0A8V0XBZ0-1", "A0A8V0XFX2-1", "A0A8V0YFL1-1", "A0A8V0YTL9-1", "A0A8V0YMB3-1", "A0A8V0X2Y2-1", "A0A8V0XCY6-1", "A0A3Q2UI62-1", "A0A8V0Y241-1", "A0A8V0Z8G2-1", "A0A8V1ABR8-1", "A0A8V1AP60-1", "A0A8V0YZM1-1", "A0A8V0ZB38-1", "A0A8V0Z466-1", "A0A8V0ZA06-1", "A0A8V1AMQ2-1", "A0A8V0ZGY3-1", "A0A8V0ZQJ2-1", "A0A8V0ZYU6-1", "A0A8V1A513-1", "A0A8V0XE48-1", "A0A8V0XQQ4-1", "A0A8V0XKG0-1" ], "evidence": [ { "id": "17989", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/17989" } ] }, { "id": "46608", "name": "", "equation": "L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A1D5PUY5-1", "Q6U1I9-1", "A0A8V0XNJ2-1", 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"A0A8V0XLV6-1", "A0A8V0XDR5-1", "E1BYH2-1", "F1NB57-1", "E1BQN6-1", "A0A8V0XU71-1", "Q5ZJH6-1", "A0A8V0Y3D1-1", "A0A8V0Y7C3-1", "A0A8V0YCY4-1", "A0A8V0YIV6-1", "A0A8V0YK18-1", "A0A8V0YM22-1", "A0A8V0YTN5-1", "A0A8V0YTP2-1", "Q5F3L1-1", "A0A8V0XU96-1", "E1C6T4-1", "A0A8V0Y3L2-1", "A0A8V0YCY8-1", "A0A8V0Y9Q1-1", "A0A8V0ZD48-1", "A0A8V0ZD60-1", "A0A8V0ZBZ2-1", "A0A8V0Z9J0-1", "A0A8V1ABF3-1", "Q8AYC9-1", "A0A8V0Z927-1", "A0A8V1A2T9-1", "Q5ZKI0-1", "Q7T0B1-1", "P10741-1", "A0A8V1AMK5-1", "P67962-1", "A0A8V0YFH4-1", "E1C848-1", "A0A8V0X8M1-1", "E1BW33-1", "A0A8V0Z283-1", "A0A8V0Z157-1", "A0A3Q2U4X3-1", "A0A8V0XW11-1", "E1BUG0-1", "A0A8V1ABP4-1", "A0A8V1AJA4-1", "A0A8V1AEH4-1", "F1NJH1-1", "A0A3Q2TRY2-1", "A0A8V0X3D6-1", "A0A1D5PD64-1", "A0A8V0XQ97-1", "R4GJB8-1", "A0A8V0X5Z8-1", "A0A8V0XG21-1", "A0A8V0XB58-1", "A0A8V0XMX8-1", "A0A8V0XQS0-1", "A0A8V0XW29-1", "A0A8V0Y074-1", "A0A8V0XXB8-1", "A0A8V0XQ14-1", "A0A8V0XI18-1", "A0A8V0XMT1-1", "A0A8V0Y457-1", "A0A8V0Y823-1", "A0A8V0Y4L8-1", "A0A8V0XND6-1", "A0A8V0Y8X9-1", "A0A8V0YZ74-1", "A0A8V0YTI1-1", "A0A8V0YLV1-1", "A0A8V0Z2E3-1", "A0A8V0YCV9-1", "A0A8V0YSH3-1", "A0A8V0YYX2-1", "A0A8V0YZY4-1", "Q5ZIU3-1", "A0A8V0YZK0-1", "A0A8V0ZKM9-1", "A0A8V0ZWC7-1", "A0A8V1A1Y7-1", "A0A8V1A069-1", "A0A8V0ZI32-1", "A0A8V0ZH91-1", "E1BQV7-1", "A0A8V0ZRX1-1", "A0A8V0ZUU9-1", "A0A8V1A0Y8-1", "A0A8V1A7E9-1", "A0A8V1A7E0-1", "A0A8V1A3T8-1", "A0A8V1A9S5-1", "A0A8V1A7M0-1", "A0A8V1A675-1", "A0A8V1A1P3-1", "A0A8V1ADT4-1", "E1BWT0-1", "A0A8V1ACF6-1", "A0A8V1ADN9-1", "A0A8V1AM12-1", "A0A8V1A4Q4-1", "Q90891-1", "F1NUX4-1", "A0A8V0ZZE4-1", "P05625-1", "P13863-1", "Q04982-2", "Q0GGW5-1", "Q6XUX0-1", "Q8QGX4-1", "Q9I9E0-1", "Q9IA88-1", "Q5ZJK4-1", "A0A1D5PTJ8-1", "E1C2I2-1", "F1NCX7-1", "F1NKW3-1", "A0A8V1A0W4-1", "A0A8V1A4J8-1", "A0A8V1ACK0-1", "F1NCY7-1", "A0A8V0X6T4-1", "A0A8V0XUM6-1", "A0A8V0XEA3-1", "A0A8V0YHH2-1", "A0A3Q2UI52-1", "A0A8V0ZZK5-1", "A0A8V0ZPX2-1", "A0A8V1ACB5-1", "A0A8V0YDH4-1", "A0A8V1AFS4-1", "A0A8V1AH12-1", "A0A8V0ZQT5-1", "A0A8V0ZFP1-1", "E1C764-1", "F1P4G3-1", "A0A8V0Y2I5-1", "A0A8V0ZLU3-1", "A0A8V0ZNP7-1", "A0A8V0Z2Z3-1", "A0A8V0YNI5-1", "Q90771-1", "A0A8V0X4P0-1", "A0A8V0X7R2-1", "A0A3Q3A664-1", "A0A8V0YGW2-1", "E1C581-1", "A0A8V1AC40-1", "A0A3Q2TUS7-1", "A0A1D5PA08-1", "A0A8V0XFW1-1", "A0A8V0XAH9-1", "A0A8V0ZFM2-1", "A0A8V1A4A1-1", "A0A8V0ZD40-1", "A0A8V0Z6T1-1", "A0A8V1A4V7-1", "A0A8V0YZF2-1", "E1BX69-1", "A0A8V0Y955-1", "A0A1D5PB73-1", "A0A1D5PV76-1", "A0A1D5PX90-1", "A0A1L1RWI9-1", "A0A3Q2TV19-1", "A0A3Q2UF44-1", "A0A8V0X4Q3-1", "A0A8V0Z124-1", "A0A8V0Z6K4-1", "A0A8V1AIY7-1", "A0A8V1AE45-1", "A0A8V0YZV9-1", "A0A8V0YYZ3-1", "A0A8V0ZUC6-1", "A0A8V0ZUU8-1", "A0A8V1AG70-1", "F1NA68-1", "F1NLR7-1", "A0A8V0Y6K1-1", "A0A8V0XS42-1", "A0A8V0YRN4-1", "A0A8V0YFP8-1", "A0A8V1A7P9-1", "A0A1D5PRN8-1", "A0A3Q3AAD7-1", "A0A3Q2TWZ8-1", "A0A8V0XBZ0-1", "A0A8V0XFX2-1", "A0A8V0YFL1-1", "A0A8V0YTL9-1", "A0A8V0YMB3-1", "A0A8V0X2Y2-1", "A0A8V0XCY6-1", "A0A3Q2UI62-1", "A0A8V0Y241-1", "A0A8V0Z8G2-1", "A0A8V1ABR8-1", "A0A8V1AP60-1", "A0A8V0YZM1-1", "A0A8V0ZB38-1", "A0A8V0Z466-1", "A0A8V0ZA06-1", "A0A8V1AMQ2-1", "A0A8V0ZGY3-1", "A0A8V0ZQJ2-1", "A0A8V0ZYU6-1", "A0A8V1A513-1", "A0A8V0XE48-1", "A0A8V0XKG0-1" ], "evidence": [ { "id": "46608", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/46608" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A1D5NWT4", "gene_name": "RPS6KA3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5NWT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NWT4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A1D5NWT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NWT4" } ] } ] }, { "uniprot_ac": "A0A1D5P0M9", "gene_name": "MAP3K13", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5P0M9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P0M9" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A1D5P0M9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P0M9" } ] } ] }, { "uniprot_ac": "A0A1D5P517", "gene_name": "PLK3", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5P517", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P517" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0A1D5P517", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P517" } ] } ] }, { "uniprot_ac": "A0A1D5P8A9", "gene_name": "SNRK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5P8A9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P8A9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A1D5P8A9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P8A9" } ] } ] }, { "uniprot_ac": "A0A1D5PA08", "gene_name": "STK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PA08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PA08" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A1D5PA08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PA08" } ] } ] }, { "uniprot_ac": "A0A1D5PB73", "gene_name": "CASK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PB73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PB73" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A1D5PB73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PB73" } ] } ] }, { "uniprot_ac": "A0A1D5PD64", "gene_name": "MAP2K3", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PD64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PD64" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A1D5PD64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PD64" } ] } ] }, { "uniprot_ac": "A0A1D5PMG2", "gene_name": "DCLK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PMG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PMG2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A1D5PMG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PMG2" } ] } ] }, { "uniprot_ac": "A0A1D5PMQ7", "gene_name": "STK40", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PMQ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PMQ7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A1D5PMQ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PMQ7" } ] } ] }, { "uniprot_ac": "A0A1D5PRN8", "gene_name": "DAPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PRN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRN8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A1D5PRN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRN8" } ] } ] }, { "uniprot_ac": "A0A1D5PTJ8", "gene_name": "MAP3K5", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PTJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PTJ8" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A1D5PTJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PTJ8" } ] } ] }, { "uniprot_ac": "A0A1D5PUY5", "gene_name": "PRKCB", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PUY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PUY5" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A1D5PUY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PUY5" } ] } ] }, { "uniprot_ac": "A0A1D5PV76", "gene_name": "STK17A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PV76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PV76" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A1D5PV76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PV76" } ] } ] }, { "uniprot_ac": "A0A1D5PX90", "gene_name": "KSR2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PX90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PX90" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A1D5PX90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PX90" } ] } ] }, { "uniprot_ac": "A0A1D5PXN4", "gene_name": "PRKCD", "activity": [ { 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"A0A8V0XFX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XFX2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XFX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XFX2" } ] } ] }, { "uniprot_ac": "A0A8V0XG21", "gene_name": "LOC107050335", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XG21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XG21" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XG21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XG21" } ] } ] }, { "uniprot_ac": "A0A8V0XI18", "gene_name": "ATM", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XI18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XI18" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XI18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XI18" } ] } ] }, { "uniprot_ac": "A0A8V0XKG0", "gene_name": "NEK9", "activity": [ { "ec_number": "2.7.11.38", "activity": "L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XKG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XKG0" } ] }, { "ec_number": "2.7.11.38", "activity": "", "evidence": [ { "id": "A0A8V0XKG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XKG0" } ] } ] }, { "uniprot_ac": "A0A8V0XLV6", "gene_name": "MAPK10", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XLV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XLV6" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0XLV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XLV6" } ] } ] }, { "uniprot_ac": "A0A8V0XMT1", "gene_name": "MOS", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XMT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMT1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XMT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMT1" } ] } ] }, { "uniprot_ac": "A0A8V0XMX8", "gene_name": "MASTL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XMX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMX8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XMX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMX8" } ] } ] }, { "uniprot_ac": "A0A8V0XND6", "gene_name": "RIOK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XND6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XND6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XND6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XND6" } ] } ] }, { "uniprot_ac": "A0A8V0XNJ2", "gene_name": "CDK8", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XNJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNJ2" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XNJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNJ2" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0XNJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNJ2" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A8V0XNJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNJ2" } ] } ] }, { "uniprot_ac": "A0A8V0XNK8", "gene_name": "PRKCQ", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XNK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNK8" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V0XNK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNK8" } ] } ] }, { "uniprot_ac": "A0A8V0XQ14", "gene_name": "PLK4", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XQ14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ14" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0A8V0XQ14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ14" } ] } ] }, { "uniprot_ac": "A0A8V0XQ97", "gene_name": "CDK14", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XQ97", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ97" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0XQ97", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ97" } ] } ] }, { "uniprot_ac": "A0A8V0XQQ4", "gene_name": "NME7", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQQ4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQQ4" } ] } ] }, { "uniprot_ac": "A0A8V0XQS0", "gene_name": "STK24", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XQS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQS0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XQS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQS0" } ] } ] }, { "uniprot_ac": "A0A8V0XS42", "gene_name": "MAP3K4", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XS42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XS42" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0XS42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XS42" } ] } ] }, { "uniprot_ac": "A0A8V0XU71", "gene_name": "MYO3A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XU71", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XU71" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XU71", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XU71" } ] } ] }, { "uniprot_ac": "A0A8V0XU96", "gene_name": "PRKD1", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XU96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XU96" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V0XU96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XU96" } ] } ] }, { "uniprot_ac": "A0A8V0XUM6", "gene_name": "LATS1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XUM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XUM6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XUM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XUM6" } ] } ] }, { "uniprot_ac": "A0A8V0XW11", "gene_name": "RPS6KA2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XW11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XW11" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XW11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XW11" } ] } ] }, { "uniprot_ac": "A0A8V0XW29", "gene_name": "CDKL2", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XW29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XW29" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0XW29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XW29" } ] } ] }, { "uniprot_ac": "A0A8V0XXB8", "gene_name": "MAPK15", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XXB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XXB8" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0XXB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XXB8" } ] } ] }, { "uniprot_ac": "A0A8V0Y074", "gene_name": "NEK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y074", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y074" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y074", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y074" } ] } ] }, { "uniprot_ac": "A0A8V0Y241", "gene_name": "LOC426385", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y241", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y241" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y241", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y241" } ] } ] }, { "uniprot_ac": "A0A8V0Y2I5", "gene_name": "CDK7", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] }, { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] } ] }, { "uniprot_ac": "A0A8V0Y3D1", "gene_name": "LRRK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y3D1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y3D1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y3D1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y3D1" } ] } ] }, { "uniprot_ac": "A0A8V0Y3L2", "gene_name": "MLK4", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y3L2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y3L2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0Y3L2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y3L2" } ] } ] }, { "uniprot_ac": "A0A8V0Y457", "gene_name": "PRPF4B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y457", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y457" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y457", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y457" } ] } ] }, { "uniprot_ac": "A0A8V0Y4L8", "gene_name": "HUNK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y4L8", "database": 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] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y7C3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y7C3" } ] } ] }, { "uniprot_ac": "A0A8V0Y823", "gene_name": "SRPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y823", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y823" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y823", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y823" } ] } ] }, { "uniprot_ac": "A0A8V0Y8X9", "gene_name": "PRKACA", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y8X9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y8X9" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "A0A8V0Y8X9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y8X9" } ] } ] }, { "uniprot_ac": "A0A8V0Y935", "gene_name": "MAST4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y935", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y935" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y935", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y935" } ] } ] }, { "uniprot_ac": "A0A8V0Y955", "gene_name": "PAK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y955", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y955" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y955", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y955" } ] } ] }, { "uniprot_ac": "A0A8V0Y9Q1", "gene_name": "LOC107055388", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y9Q1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9Q1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y9Q1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9Q1" } ] } ] }, { "uniprot_ac": "A0A8V0YCV9", "gene_name": "SIK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YCV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCV9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YCV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCV9" } ] } ] }, { 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O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YFH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFH4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YFH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFH4" } ] } ] }, { "uniprot_ac": "A0A8V0YFL1", "gene_name": "CDK19", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YFL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFL1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0YFL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFL1" } ] } ] }, { "uniprot_ac": "A0A8V0YFP8", "gene_name": "RIPK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YFP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFP8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YFP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFP8" } ] } ] }, { "uniprot_ac": "A0A8V0YFR6", "gene_name": "TNIK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YFR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFR6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YFR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFR6" } ] } ] }, { "uniprot_ac": "A0A8V0YGW2", "gene_name": "STK32B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YGW2", "database": "UniProtKB", "url": 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"ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YHN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHN2" } ] } ] }, { "uniprot_ac": "A0A8V0YIV6", "gene_name": "DYRK1A", "activity": [ { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] }, { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] } ] }, { "uniprot_ac": "A0A8V0YJP9", "gene_name": "RIOK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YJP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJP9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YJP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJP9" } ] } ] }, { "uniprot_ac": "A0A8V0YK18", "gene_name": "CDC42BPB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YK18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK18" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YK18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK18" } ] } ] }, { "uniprot_ac": "A0A8V0YKK3", "gene_name": "MAP4K4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YKK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKK3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YKK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKK3" } ] } ] }, { "uniprot_ac": "A0A8V0YLV1", "gene_name": "MARK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YLV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLV1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YLV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLV1" } ] } ] }, { "uniprot_ac": "A0A8V0YM22", "gene_name": "MYO3AL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YM22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM22" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YM22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM22" } ] } ] }, { "uniprot_ac": "A0A8V0YM96", "gene_name": "STK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YM96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM96" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YM96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM96" } ] } ] }, { "uniprot_ac": "A0A8V0YMB3", "gene_name": "STK32A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YMB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMB3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YMB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMB3" } ] } ] }, { "uniprot_ac": "A0A8V0YMN5", "gene_name": "BRAF", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YMN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMN5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YMN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMN5" } ] } ] }, { "uniprot_ac": "A0A8V0YNI5", "gene_name": "NIM1K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YNI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNI5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YNI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNI5" } ] } ] }, { "uniprot_ac": "A0A8V0YRC9", "gene_name": "TNK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YRC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRC9" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YRC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRC9" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0YRC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRC9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YRC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRC9" } ] } ] }, { "uniprot_ac": "A0A8V0YRN4", "gene_name": "GAK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YRN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRN4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YRN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRN4" } ] } ] }, { "uniprot_ac": "A0A8V0YSH3", "gene_name": "RPS6KA6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YSH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSH3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": 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"https://www.uniprot.org/uniprotkb/A0A8V0YTL9" } ] } ] }, { "uniprot_ac": "A0A8V0YTN5", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTN5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTN5" } ] } ] }, { "uniprot_ac": "A0A8V0YTP2", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTP2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTP2" } ] } ] }, { "uniprot_ac": "A0A8V0YXZ5", "gene_name": "CDC42BPA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YXZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXZ5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YXZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXZ5" } ] } ] }, { "uniprot_ac": "A0A8V0YYX2", "gene_name": "PAK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YYX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYX2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YYX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYX2" } ] } ] }, { "uniprot_ac": "A0A8V0YYZ3", "gene_name": "SPEG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YYZ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYZ3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YYZ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYZ3" } ] } ] }, { "uniprot_ac": "A0A8V0YZ74", "gene_name": "MAP2K5", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZ74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZ74" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V0YZ74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZ74" } ] } ] }, { "uniprot_ac": "A0A8V0YZF2", "gene_name": "PAK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZF2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YZF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZF2" } ] } ] }, { "uniprot_ac": "A0A8V0YZK0", "gene_name": "MAP3K6", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZK0" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0YZK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZK0" } ] } ] }, { "uniprot_ac": "A0A8V0YZM1", "gene_name": "MOK", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZM1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0YZM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZM1" } ] }, { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZM1" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0YZM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZM1" } ] } ] }, { "uniprot_ac": "A0A8V0YZV9", "gene_name": "ATR", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZV9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YZV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZV9" } ] } ] }, { "uniprot_ac": "A0A8V0YZY4", "gene_name": "SBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZY4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YZY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZY4" } ] } ] }, { "uniprot_ac": "A0A8V0Z124", "gene_name": "VRK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z124", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z124" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z124", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z124" } ] } ] }, { "uniprot_ac": "A0A8V0Z157", "gene_name": "MARK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z157", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z157" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z157", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z157" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A8V0Z157", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z157" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z157", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z157" } ] } ] }, { "uniprot_ac": "A0A8V0Z1X0", "gene_name": "MAP4K3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z1X0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1X0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z1X0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1X0" } ] } ] }, { "uniprot_ac": "A0A8V0Z283", "gene_name": "MARK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z283", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z283" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z283", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z283" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A8V0Z283", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z283" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z283", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z283" } ] } ] }, { "uniprot_ac": "A0A8V0Z2E3", "gene_name": "PDIK1L", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z2E3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2E3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z2E3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2E3" } ] } ] }, { "uniprot_ac": "A0A8V0Z2Z3", "gene_name": "AAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z2Z3", "database": 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"ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z807", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z807" } ] } ] }, { "uniprot_ac": "A0A8V0Z8G2", "gene_name": "TTBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z8G2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8G2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z8G2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8G2" } ] } ] }, { "uniprot_ac": "A0A8V0Z8T4", "gene_name": "RPS6KC1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z8T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8T4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z8T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8T4" } ] } ] }, { "uniprot_ac": "A0A8V0Z927", "gene_name": "PINK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z927", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z927" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z927", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z927" } ] } ] }, { "uniprot_ac": "A0A8V0Z930", "gene_name": "CAMK2B", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z930", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z930" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V0Z930", "database": "UniProtKB", "url": 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"uniprot_ac": "A0A8V0ZA45", "gene_name": "MAP4K5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZA45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA45" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZA45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA45" } ] } ] }, { "uniprot_ac": "A0A8V0ZB33", "gene_name": "CAMK2G", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZB33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB33" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V0ZB33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB33" } ] } ] }, { "uniprot_ac": "A0A8V0ZB38", "gene_name": "CIITA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZB38", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB38" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZB38", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB38" } ] } ] }, { "uniprot_ac": "A0A8V0ZBN6", "gene_name": "MAP2K1", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZBN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBN6" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V0ZBN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBN6" } ] } ] }, { "uniprot_ac": "A0A8V0ZBZ2", "gene_name": "MAP3K9", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZBZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBZ2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0ZBZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBZ2" } ] } ] }, { "uniprot_ac": "A0A8V0ZC16", "gene_name": "KALRN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZC16", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC16" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZC16", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC16" } ] } ] }, { "uniprot_ac": "A0A8V0ZD40", "gene_name": "CDC2L1", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD40" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD40" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A8V0ZD40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD40" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0ZD40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD40" } ] } ] }, { "uniprot_ac": "A0A8V0ZD48", "gene_name": "PRKCE", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD48" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V0ZD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD48" } ] } ] }, { "uniprot_ac": "A0A8V0ZD60", "gene_name": "STK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD60" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZD60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD60" } ] } ] }, { "uniprot_ac": "A0A8V0ZD70", "gene_name": "DCLK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD70" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZD70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD70" } ] } ] }, { "uniprot_ac": "A0A8V0ZDW9", "gene_name": "NEK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZDW9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDW9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZDW9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDW9" } ] } ] }, { "uniprot_ac": "A0A8V0ZFM2", "gene_name": "LMTK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZFM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFM2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZFM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFM2" } ] } ] }, { "uniprot_ac": "A0A8V0ZFP1", "gene_name": "TTBK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZFP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFP1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZFP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFP1" } ] } ] }, { "uniprot_ac": "A0A8V0ZFT3", "gene_name": "LRRK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZFT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFT3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZFT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFT3" } ] } ] }, { "uniprot_ac": "A0A8V0ZGY3", "gene_name": "HIPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZGY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGY3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZGY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGY3" } ] } ] }, { "uniprot_ac": "A0A8V0ZH91", "gene_name": "WNK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZH91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH91" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZH91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH91" } ] } ] }, { "uniprot_ac": "A0A8V0ZI32", "gene_name": "STK16", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZI32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI32" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZI32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI32" } ] } ] }, { "uniprot_ac": "A0A8V0ZK64", "gene_name": "PDPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZK64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK64" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZK64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK64" } ] } ] }, { "uniprot_ac": "A0A8V0ZKA2", "gene_name": "EIF2AK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZKA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKA2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZKA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKA2" } ] } ] }, { "uniprot_ac": "A0A8V0ZKM9", "gene_name": "STK36", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZKM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKM9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZKM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKM9" } ] } ] }, { "uniprot_ac": "A0A8V0ZLU3", "gene_name": "TLK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": 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"ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZPX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPX2" } ] } ] }, { "uniprot_ac": "A0A8V0ZQJ2", "gene_name": "RPS6KB2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZQJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQJ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZQJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQJ2" } ] } ] }, { "uniprot_ac": "A0A8V0ZQT5", "gene_name": "SLC13A3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZQT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQT5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZQT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQT5" } ] } ] }, { "uniprot_ac": "A0A8V0ZRX1", "gene_name": "SETD6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZRX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRX1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZRX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRX1" } ] }, { "ec_number": "2.1.1.-", "activity": "", "evidence": [ { "id": "A0A8V0ZRX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRX1" } ] } ] }, { "uniprot_ac": "A0A8V0ZSB4", "gene_name": "SIK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZSB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSB4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZSB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSB4" } ] } ] }, { "uniprot_ac": "A0A8V0ZSP4", "gene_name": "PKN2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZSP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSP4" } ] }, { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZSP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSP4" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V0ZSP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSP4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZSP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSP4" } ] } ] }, { "uniprot_ac": "A0A8V0ZT63", "gene_name": "STK25", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZT63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT63" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZT63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT63" } ] } ] }, { "uniprot_ac": "A0A8V0ZUC6", "gene_name": "PAK6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZUC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUC6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZUC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUC6" } ] } ] }, { "uniprot_ac": "A0A8V0ZUL0", "gene_name": "PASK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZUL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUL0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZUL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUL0" } ] } ] }, { "uniprot_ac": "A0A8V0ZUU8", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZUU8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUU8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZUU8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUU8" } ] } ] }, { "uniprot_ac": "A0A8V0ZUU9", "gene_name": "MKNK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZUU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUU9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZUU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUU9" } ] } ] }, { "uniprot_ac": "A0A8V0ZWC7", "gene_name": "EIF2AK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZWC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWC7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZWC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWC7" } ] } ] }, { "uniprot_ac": "A0A8V0ZWW1", "gene_name": "MAP3K12", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZWW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWW1" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0ZWW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWW1" } ] } ] }, { "uniprot_ac": "A0A8V0ZXQ9", "gene_name": "PRKG1", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZXQ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXQ9" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "A0A8V0ZXQ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXQ9" } ] } ] }, { "uniprot_ac": "A0A8V0ZYU6", "gene_name": "TNNI3K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZYU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZYU6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZYU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZYU6" } ] } ] }, { "uniprot_ac": "A0A8V0ZZE4", "gene_name": "OBSCN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZZE4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZE4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZZE4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZE4" } ] } ] }, { "uniprot_ac": "A0A8V0ZZK5", "gene_name": "STK38", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZZK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZK5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZZK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZK5" } ] } ] }, { "uniprot_ac": "A0A8V0ZZV3", "gene_name": "MYO3B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZZV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZV3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZZV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZV3" } ] } ] }, { "uniprot_ac": "A0A8V1A069", "gene_name": "TESK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A069", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A069" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V1A069", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A069" } ] } ] }, { "uniprot_ac": "A0A8V1A0W4", "gene_name": "ULK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A0W4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0W4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A0W4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0W4" } ] } ] }, { "uniprot_ac": "A0A8V1A0Y8", "gene_name": "MAST2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A0Y8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0Y8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A0Y8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0Y8" } ] } ] }, { "uniprot_ac": "A0A8V1A1P3", "gene_name": "SRPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A1P3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1P3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A1P3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1P3" } ] } ] }, { "uniprot_ac": "A0A8V1A1Y7", "gene_name": "CDK2", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A1Y7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1Y7" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V1A1Y7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1Y7" } ] } ] }, { "uniprot_ac": "A0A8V1A2T9", "gene_name": "MAP3K14", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A2T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2T9" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V1A2T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2T9" } ] } ] }, { "uniprot_ac": "A0A8V1A3T8", "gene_name": "MAST3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A3T8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3T8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A3T8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3T8" } ] } ] }, { "uniprot_ac": "A0A8V1A4A1", "gene_name": "CAMKK2", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4A1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4A1" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V1A4A1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4A1" } ] } ] }, { "uniprot_ac": "A0A8V1A4J8", "gene_name": "MAPKAPK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4J8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4J8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A4J8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4J8" } ] } ] }, { "uniprot_ac": "A0A8V1A4Q4", "gene_name": "MAPK3", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4Q4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4Q4" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V1A4Q4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4Q4" } ] } ] }, { "uniprot_ac": "A0A8V1A4V7", "gene_name": "HIPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4V7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4V7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A4V7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4V7" } ] } ] }, { "uniprot_ac": "A0A8V1A513", "gene_name": "DAPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A513", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A513" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A513", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A513" } ] } ] }, { "uniprot_ac": "A0A8V1A675", "gene_name": "CSNK1G2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A675", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A675" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A675", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A675" } ] } ] }, { "uniprot_ac": "A0A8V1A7E0", "gene_name": "DYRK3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7E0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E0" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V1A7E0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E0" } ] } ] }, { "uniprot_ac": "A0A8V1A7E9", "gene_name": "SIK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7E9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A7E9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E9" } ] } ] }, { "uniprot_ac": "A0A8V1A7M0", "gene_name": "STK39", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7M0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7M0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A7M0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7M0" } ] } ] }, { "uniprot_ac": "A0A8V1A7P9", "gene_name": "DCAF1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A7P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P9" } ] } ] }, { "uniprot_ac": "A0A8V1A9S5", "gene_name": "NUAK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A9S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9S5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A9S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9S5" } ] } ] }, { "uniprot_ac": "A0A8V1ABF3", "gene_name": "PRKAA2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] } ] }, { "uniprot_ac": "A0A8V1ABP4", "gene_name": "DSTYK", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABP4" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V1ABP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABP4" } ] } ] }, { "uniprot_ac": "A0A8V1ABR8", "gene_name": "CAMK4L", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABR8" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V1ABR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABR8" } ] } ] }, { "uniprot_ac": "A0A8V1AC40", "gene_name": "CDK18", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AC40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC40" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V1AC40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC40" } ] } ] }, { "uniprot_ac": "A0A8V1ACB5", "gene_name": "MAPK13", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACB5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V1ACB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACB5" } ] } ] }, { "uniprot_ac": "A0A8V1ACF6", "gene_name": "PIM1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACF6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ACF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACF6" } ] } ] }, { "uniprot_ac": "A0A8V1ACK0", "gene_name": "MAPKAPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACK0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ACK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACK0" } ] } ] }, { "uniprot_ac": "A0A8V1ACW2", "gene_name": "WNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACW2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ACW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACW2" } ] } ] }, { "uniprot_ac": "A0A8V1ADF0", "gene_name": "MAP2K2", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ADF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADF0" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V1ADF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADF0" } ] } ] }, { "uniprot_ac": "A0A8V1ADN9", "gene_name": "NLK", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ADN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADN9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V1ADN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADN9" } ] } ] }, { "uniprot_ac": "A0A8V1ADT4", "gene_name": "MKNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ADT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADT4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ADT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADT4" } ] } ] }, { "uniprot_ac": "A0A8V1AE45", "gene_name": "ERN1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AE45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE45" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AE45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE45" } ] } ] }, { "uniprot_ac": "A0A8V1AEH4", "gene_name": "STK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AEH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEH4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AEH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEH4" } ] } ] }, { "uniprot_ac": "A0A8V1AFS4", "gene_name": "STKLD1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AFS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFS4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AFS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFS4" } ] } ] }, { "uniprot_ac": "A0A8V1AG70", "gene_name": "LOC100857512", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AG70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AG70" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AG70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AG70" } ] } ] }, { "uniprot_ac": "A0A8V1AH12", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AH12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH12" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AH12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH12" } ] } ] }, { "uniprot_ac": "A0A8V1AHA8", "gene_name": "NEK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AHA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHA8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AHA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHA8" } ] } ] }, { "uniprot_ac": "A0A8V1AIY7", "gene_name": "AATK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AIY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIY7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AIY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIY7" } ] } ] }, { "uniprot_ac": "A0A8V1AJA4", "gene_name": "RPS6KB1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AJA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJA4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AJA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJA4" } ] } ] }, { "uniprot_ac": "A0A8V1AKW4", "gene_name": "MAP2K4", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AKW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKW4" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V1AKW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKW4" } ] } ] }, { "uniprot_ac": "A0A8V1AM12", "gene_name": "GSG2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AM12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM12" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AM12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM12" } ] } ] }, { "uniprot_ac": "A0A8V1AMK5", "gene_name": "PRKCA", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AMK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMK5" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V1AMK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMK5" } ] } ] }, { "uniprot_ac": "A0A8V1AMQ2", "gene_name": "CAMKK1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AMQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMQ2" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V1AMQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMQ2" } ] } ] }, { "uniprot_ac": "A0A8V1AP60", "gene_name": "KSR1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AP60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP60" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AP60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP60" } ] } ] }, { "uniprot_ac": "E1BQN6", "gene_name": "PRKCZ", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BQN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQN6" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1BQN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQN6" } ] } ] }, { "uniprot_ac": "E1BQV7", "gene_name": "SLK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BQV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQV7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BQV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQV7" } ] } ] }, { "uniprot_ac": "E1BUG0", "gene_name": "CDK12", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] } ] }, { "uniprot_ac": "E1BW33", "gene_name": "SMG1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BW33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BW33" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BW33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BW33" } ] } ] }, { "uniprot_ac": "E1BWA3", "gene_name": "PRKCI", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BWA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWA3" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1BWA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWA3" } ] } ] }, { "uniprot_ac": "E1BWT0", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BWT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWT0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BWT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWT0" } ] } ] }, { "uniprot_ac": "E1BX69", "gene_name": "EIF2AK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BX69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BX69" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BX69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BX69" } ] } ] }, { "uniprot_ac": "E1BY69", "gene_name": "PIM3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BY69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BY69" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BY69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BY69" } ] } ] }, { "uniprot_ac": "E1BYH2", "gene_name": "TAOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BYH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BYH2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BYH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BYH2" } ] } ] }, { "uniprot_ac": "E1C093", "gene_name": "PIK3CG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.154", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.154", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] } ] }, { "uniprot_ac": "E1C2I2", "gene_name": "MASTL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C2I2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C2I2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C2I2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C2I2" } ] } ] }, { "uniprot_ac": "E1C581", "gene_name": "TBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C581", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C581" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C581", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C581" } ] } ] }, { "uniprot_ac": "E1C6T4", "gene_name": "PRKD3", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C6T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C6T4" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1C6T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C6T4" } ] } ] }, { "uniprot_ac": "E1C764", "gene_name": "BMP2K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C764", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C764" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C764", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C764" } ] } ] }, { "uniprot_ac": "E1C848", "gene_name": "MAP3K8", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C848", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C848" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1C848", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C848" } ] } ] }, { "uniprot_ac": "F1NA68", "gene_name": "CDK3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NA68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NA68" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1NA68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NA68" } ] } ] }, { "uniprot_ac": "F1NB57", "gene_name": "PLK2", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NB57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NB57" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "F1NB57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NB57" } ] } ] }, { "uniprot_ac": "F1NBT0", "gene_name": "STK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NBT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NBT0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1NBT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NBT0" } ] } ] }, { "uniprot_ac": "F1NCX7", "gene_name": "PLK1", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NCX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCX7" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "F1NCX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCX7" } ] } ] }, { "uniprot_ac": "F1NCY7", "gene_name": "MAPKAPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NCY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCY7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1NCY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCY7" } ] } ] }, { "uniprot_ac": "F1NJH1", "gene_name": "PRKCH", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NJH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NJH1" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1NJH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NJH1" } ] } ] }, { "uniprot_ac": "F1NKW3", "gene_name": "MAP3K15", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NKW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NKW3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1NKW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NKW3" } ] } ] }, { "uniprot_ac": "F1NLR7", "gene_name": "CLK3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NLR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NLR7" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "F1NLR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NLR7" } ] } ] }, { "uniprot_ac": "F1NUX4", "gene_name": "MTOR", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NUX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NUX4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1NUX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NUX4" } ] } ] }, { "uniprot_ac": "F1NVF2", "gene_name": "MAP2K6", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NVF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NVF2" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "F1NVF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NVF2" } ] } ] }, { "uniprot_ac": "F1P011", "gene_name": "CAMK2A", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1P011", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P011" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "F1P011", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P011" } ] } ] }, { "uniprot_ac": "F1P356", "gene_name": "NUAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1P356", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P356" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1P356", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P356" } ] } ] }, { "uniprot_ac": "F1P4G3", "gene_name": "HIPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1P4G3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P4G3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1P4G3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P4G3" } ] } ] }, { "uniprot_ac": "P05625", "gene_name": "RAF1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P05625", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05625" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P05625", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05625" } ] } ] }, { "uniprot_ac": "P10741", "gene_name": "MOS", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P10741", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P10741" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P10741", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P10741" } ] } ] }, { "uniprot_ac": "P13863", "gene_name": "CDK1", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P13863", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13863" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "P13863", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13863" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "P13863", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13863" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "P13863", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13863" } ] } ] }, { "uniprot_ac": "P18652", "gene_name": "RPS6KA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P18652", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P18652" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P18652", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P18652" } ] } ] }, { "uniprot_ac": "P21868", "gene_name": "CSNK2A1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P21868", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P21868" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P21868", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P21868" } ] } ] }, { "uniprot_ac": "P21869", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P21869", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P21869" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P21869", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P21869" } ] } ] }, { "uniprot_ac": "P53666", "gene_name": "LIMK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P53666", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P53666" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P53666", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P53666" } ] } ] }, { "uniprot_ac": "P67962", "gene_name": "CSNK1A1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P67962", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P67962" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P67962", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P67962" } ] } ] }, { "uniprot_ac": "P79996", "gene_name": "MAPK9", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P79996", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P79996" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "P79996", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P79996" } ] } ] }, { "uniprot_ac": "Q04982", "gene_name": "BRAF", "activity": [ { "ec_number": "2.7.11.1", 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"https://www.uniprot.org/uniprotkb/A0A8V0YGW9/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGW9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGW9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LRIG3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGW9", "locus": { "chromosome": "1", "start_pos": 31862744, "end_pos": 31939424, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010014194", "url": "https://www.ensembl.org/id/ENSGALG00010014194" } ] } } ], "crossref": [ { "id": "A0A8V0YGW9", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YGW9", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd05763", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05763", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "417813", "url": "https://www.ncbi.nlm.nih.gov/gene/417813", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000483", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000483", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001611", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001611", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003591", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003591", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003598", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003598", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013098", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013098", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR026906", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026906", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050467", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050467", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:417813", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417813", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YGW9", "url": "https://www.orthodb.org/?gene=A0A8V0YGW9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YN76", "url": "https://www.orthodb.org/?gene=A0A8V0YN76", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YQ06", "url": "https://www.orthodb.org/?gene=A0A8V0YQ06", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YV24", "url": "https://www.orthodb.org/?gene=A0A8V0YV24", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YV35", "url": "https://www.orthodb.org/?gene=A0A8V0YV35", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45842", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45842", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45842:SF16", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45842:SF16", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07679", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07679", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13306", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13306", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13855", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13855", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13927", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13927", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YGW9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGW9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YGW9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGW9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YN76", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN76", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YN76-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN76-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQ06", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ06", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQ06-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ06-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YV24", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YV24", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YV24-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YV24-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YV35", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YV35", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YV35-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YV35-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPRVASAALPALLLLLLGGPAAARCPVSCRCAGHLVACSRLEPNRLPERLPRGAVQLDLSHNKLSSIKANFLDHLHSLREVKLNNNELEIIPNLGPVSANITLLSLTSNKIANILSEHLKPFQSLETLDLSNNNISELKMSSFPSLQLKYLYINSNRITSMEPGTFDNLSTTLQVLKLNRNKISAIPQKMFKLSHLQHLELNRNKIKKIDGLTFQGLPALKSLKLQRNGITRLMDGAFWGLTNMEVLQLDHNNLTEVTKGWLYGLLMLQQLHLSQNAISRISPDAWEFCQKLSELDLTFNHLARLDDSSFAGLSVLVGLYIGSNKVNYIADCAFRGLSSLQTLDLKNNEISWTIEDMNGAFSGLDKLRNLILQGNRIRSITKKAFSGLDALEHLDLSNNAIMSVQGNAFSQMKKLKELHLNTSSLLCDCQLKWLPQWVSENNFQNFVNASCAHPQLLKGRSIFAVSLDAFVCDDFPKPQITVQPETQSAIKGSNLSFVCSAASSSDSPMTFAWKKDNELLHDAEMENYAHLRAQGGEVMEYTTILRLRNVEFSSEGKYQCVISNHFGSSYSIKAKLTVNMLPSFTKIPMDLTIRAGAMARLECAAVGHPVPQIAWQKDGGTDFPAARKRRMHVMPEDDVFFIVDVKIEDTGVYSCTAQNTAGSISANATLTVLAYTFFSETPSFLRPLLDRTVTKGETAVLQCIAGGSPPPRLNWTKDDSPLVVTERHFFAASNQLLIIVDTDVEDAGKYTCEMSNTLGTERGNIRLNVIPTPTCDSPQNITPALDDDGWATVGIVIIAVVCCVVGTSLVWVVIIYHTRRRNEDCSITNTDETNLPADIPSYLSSQGTLAERQDGYGSSENGSHHQFLTSSVGGYFLQQRDSNGICHLDNGSETDLDGVADPFLCHYLGTSGTMYLKGNTYSSETFEACSPSCSPDQRTASLDPYESGYLKKKECCQYSLPLEDPFDQCIGVIGMQATGSKLINSIYTQNEGTGLKSRSLNSDKLDLNRSLEPSSIISNSTFMGTFGKPVWRPQLDSLSGRRQPAASCQPKTSHNNPHSSLDFDPEADEDGRERTVSRGQNSIYNYKQSFENFRTFNFQSCDLDT", "length": 1105, "header": "tr|A0A8V0YGW9-1|A0A8V0YGW9_CHICK Isoform 1 of Leucine rich repeats and immunoglobulin like domains 3 OS=Gallus gallus OX=9031 GN=LRIG3 PE=4 SV=1 CANONICAL=A0A8V0YGW9-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YGW9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGW9/entry#A0A8V0YGW9-1", "sequence": { "sequence": "MPRVASAALPALLLLLLGGPAAARCPVSCRCAGHLVACSRLEPNRLPERLPRGAVQLDLSHNKLSSIKANFLDHLHSLREVKLNNNELEIIPNLGPVSANITLLSLTSNKIANILSEHLKPFQSLETLDLSNNNISELKMSSFPSLQLKYLYINSNRITSMEPGTFDNLSTTLQVLKLNRNKISAIPQKMFKLSHLQHLELNRNKIKKIDGLTFQGLPALKSLKLQRNGITRLMDGAFWGLTNMEVLQLDHNNLTEVTKGWLYGLLMLQQLHLSQNAISRISPDAWEFCQKLSELDLTFNHLARLDDSSFAGLSVLVGLYIGSNKVNYIADCAFRGLSSLQTLDLKNNEISWTIEDMNGAFSGLDKLRNLILQGNRIRSITKKAFSGLDALEHLDLSNNAIMSVQGNAFSQMKKLKELHLNTSSLLCDCQLKWLPQWVSENNFQNFVNASCAHPQLLKGRSIFAVSLDAFVCDDFPKPQITVQPETQSAIKGSNLSFVCSAASSSDSPMTFAWKKDNELLHDAEMENYAHLRAQGGEVMEYTTILRLRNVEFSSEGKYQCVISNHFGSSYSIKAKLTVNMLPSFTKIPMDLTIRAGAMARLECAAVGHPVPQIAWQKDGGTDFPAARKRRMHVMPEDDVFFIVDVKIEDTGVYSCTAQNTAGSISANATLTVLAYTFFSETPSFLRPLLDRTVTKGETAVLQCIAGGSPPPRLNWTKDDSPLVVTERHFFAASNQLLIIVDTDVEDAGKYTCEMSNTLGTERGNIRLNVIPTPTCDSPQNITPALDDDGWATVGIVIIAVVCCVVGTSLVWVVIIYHTRRRNEDCSITNTDETNLPADIPSYLSSQGTLAERQDGYGSSENGSHHQFLTSSVGGYFLQQRDSNGICHLDNGSETDLDGVADPFLCHYLGTSGTMYLKGNTYSSETFEACSPSCSPDQRTASLDPYESGYLKKKECCQYSLPLEDPFDQCIGVIGMQATGSKLINSIYTQNEGTGLKSRSLNSDKLDLNRSLEPSSIISNSTFMGTFGKPVWRPQLDSLSGRRQPAASCQPKTSHNNPHSSLDFDPEADEDGRERTVSRGQNSIYNYKQSFENFRTFNFQSCDLDT", "length": 1105, "header": "tr|A0A8V0YGW9-1|A0A8V0YGW9_CHICK Isoform 1 of Leucine rich repeats and immunoglobulin like domains 3 OS=Gallus gallus OX=9031 GN=LRIG3 PE=4 SV=1 CANONICAL=A0A8V0YGW9-1" }, "locus": { "chromosome": "1", "start_pos": 31906613, "end_pos": 31863658, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034238.1", "url": "https://www.ensembl.org/id/ENSGALT00010034238.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020115.1", "url": "https://www.ensembl.org/id/ENSGALP00010020115.1" } ] } }, { "isoform_ac": "A0A8V0YN76-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGW9/entry#A0A8V0YN76-1", "sequence": { "sequence": "MPRVASAALPALLLLLLGGPAAARCPVSCRCAGHLVACSRLEPNRLPERLPRGAVQLDLSHNKLSSIKANFLDHLHSLREVKLNNNELEIIPNLGPVSANITLLSFFSKLRLANLGWYINSNRITSMEPGTFDNLSTTLQVLKLNRNKISAIPQKMFKLSHLQHLELNRNKIKKIDGLTFQGLPALKSLKLQRNGITRLMDGAFWGLTNMEVLQLDHNNLTEVTKGWLYGLLMLQQLHLSQNAISRISPDAWEFCQKLSELDLTFNHLARLDDSSFAGLSVLVGLYIGSNKVNYIADCAFRGLSSLQTLDLKNNEISWTIEDMNGAFSGLDKLRNLILQGNRIRSITKKAFSGLDALEHLDLSNNAIMSVQGNAFSQMKKLKELHLNTSSLLCDCQLKWLPQWVSENNFQNFVNASCAHPQLLKGRSIFAVSLDAFVCDDFPKPQITVQPETQSAIKGSNLSFVCSAASSSDSPMTFAWKKDNELLHDAEMENYAHLRAQGGEVMEYTTILRLRNVEFSSEGKYQCVISNHFGSSYSIKAKLTVNMLPSFTKIPMDLTIRAGAMARLECAAVGHPVPQIAWQKDGGTDFPAARKRRMHVMPEDDVFFIVDVKIEDTGVYSCTAQNTAGSISANATLTVLETPSFLRPLLDRTVTKGETAVLQCIAGGSPPPRLNWTKDDSPLVVTERHFFAASNQLLIIVDTDVEDAGKYTCEMSNTLGTERGNIRLNVIPTPTCDSPQNITPALDDDGWATVGIVIIAVVCCVVGTSLVWVVIIYHTRRRNEDCSITNTDETNLPADIPSYLSSQGTLAERQDGYGSSENGSHHQFLTSSVGGYFLQQRDSNGICHLDNGSETDLDGVADPFLCHYLGTSGTMYLKGNTYSSETFEACSPSCSPDQRTASLDPYESGYLKKKECCQYSLPLEDPFDQCIGVIGMQATGSKLINSIYTQNEGTGLKSRSLNSDKLDLNRSLEPSSIISNSTFMGTFGKPVWRPQLDSLSGRRQPAASCQPKTSHNNPHSSLDFDPEADEDGRERTVSRGQNSIYNYKQSFENFRTFNFQSCDLDT", "length": 1065, "header": "tr|A0A8V0YN76-1|A0A8V0YN76_CHICK Computationally mapped isoform of Leucine rich repeats and immunoglobulin like domains 3 OS=Gallus gallus OX=9031 GN=LRIG3 PE=4 SV=1 CANONICAL=A0A8V0YGW9-1" }, "locus": { "chromosome": "1", "start_pos": 31906613, "end_pos": 31863658, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034200.1", "url": "https://www.ensembl.org/id/ENSGALT00010034200.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020092.1", "url": "https://www.ensembl.org/id/ENSGALP00010020092.1" } ] } }, { "isoform_ac": "A0A8V0YQ06-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGW9/entry#A0A8V0YQ06-1", "sequence": { "sequence": "MPRVASAALPALLLLLLGGPAAARCPVSCRCAGHLVACSRLEPNRLPERLPRGAVQLDLSHNKLSSIKANFLDHLHSLREVKLNNNELEIIPNLGPVSANITLLSLTSNKIANILSEHLKPFQSLETLDLSNNNISELKMSSFPSLQLKYLYINSNRITSMEPGTFDNLSTTLQVLKLNRNKISAIPQKMFKLSHLQHLELNRNKIKKIDGLTFQGLPALKSLKLQRNGITRLMDGAFWGLTNMEVLDLTFNHLARLDDSSFAGLSVLVGLYIGSNKVNYIADCAFRGLSSLQTLDLKNNEISWTIEDMNGAFSGLDKLRNLILQGNRIRSITKKAFSGLDALEHLDLSNNAIMSVQGNAFSQMKKLKELHLNTSSLLCDCQLKWLPQWVSENNFQNFVNASCAHPQLLKGRSIFAVSLDAFVCDDFPKPQITVQPETQSAIKGSNLSFVCSAASSSDSPMTFAWKKDNELLHDAEMENYAHLRAQGGEVMEYTTILRLRNVEFSSEGKYQCVISNHFGSSYSIKAKLTVNMLPSFTKIPMDLTIRAGAMARLECAAVGHPVPQIAWQKDGGTDFPAARKRRMHVMPEDDVFFIVDVKIEDTGVYSCTAQNTAGSISANATLTVLETPSFLRPLLDRTVTKGETAVLQCIAGGSPPPRLNWTKDDSPLVVTERHFFAASNQLLIIVDTDVEDAGKYTCEMSNTLGTERGNIRLNVIPTPTCDSPQNITPALDDDGWATVGIVIIAVVCCVVGTSLVWVVIIYHTRRRNEDCSITNTDETNLPADIPSYLSSQGTLAERQDGYGSSENGSHHQFLTSSVGGYFLQQRDSNGICHLDNGSETDLDGVADPFLCHYLGTSGTMYLKGNTYSSETFEACSPSCSPDQRTASLDPYESGYLKKKECCQYSLPLEDPFDQCIGVIGMQATGSKLINSIYTQNEGTGLKSRSLNSDKLDLNRSLEPSSIISNSTFMGTFGKPVWRPQLDSLSGRRQPAASCQPKTSHNNPHSSLDFDPEADEDGRERTVSRGQNSIYNYKQSFENFRTFNFQSCDLDT", "length": 1051, "header": "tr|A0A8V0YQ06-1|A0A8V0YQ06_CHICK Computationally mapped isoform of Leucine rich repeats and immunoglobulin like domains 3 OS=Gallus gallus OX=9031 GN=LRIG3 PE=4 SV=1 CANONICAL=A0A8V0YGW9-1" }, "locus": { "chromosome": "1", "start_pos": 31906613, "end_pos": 31863658, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034221.1", "url": "https://www.ensembl.org/id/ENSGALT00010034221.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020103.1", "url": "https://www.ensembl.org/id/ENSGALP00010020103.1" } ] } }, { "isoform_ac": "A0A8V0YV24-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGW9/entry#A0A8V0YV24-1", "sequence": { "sequence": "MPRVASAALPALLLLLLGGPAAARCPVSCRCAGHLVACSRLEPNRLPERLPRGAVQLDLSHNKLSSIKANFLDHLHSLREVKLNNNELEIIPNLGPVSANITLLSLTSNKIANILSEHLKPFQSLETLDLSNNNISELKMSSFPSLQLKYLYINSNRITSMEPGTFDNLSTTLQVLKLNRNKISAIPQKMFKLSHLQHLELNRNKIKKIDGLTFQGLPALKSLKLQRNGITRLMDGAFWGLTNMEVLQLDHNNLTEVTKGWLYGLLMLQQLHLSQNAISRISPDAWEFCQKLSELDLTFNHLARLDDSSFAGLSVLVGLYIGSNKVNYIADCAFRGLSSLQTLDLKNNEISWTIEDMNGAFSGLDKLRNLILQGNRIRSITKKAFSGLDALEHLDLSNNAIMSVQGNAFSQMKKLKELHLNTSSLLCDCQLKWLPQWVSENNFQNFVNASCAHPQLLKGRSIFAVSLDAFVCDDFPKPQITVQPETQSAIKGSNLSFVCSAASSSDSPMTFAWKKDNELLHDAEMENYAHLRAQGGEVMEYTTILRLRNVEFSSEGKYQCVISNHFGSSYSIKAKLTVNMLPSFTKIPMDLTIRAGAMARLECAAVGHPVPQIAWQKDGGTDFPAARKRRMHVMPEDDVFFIVDVKIEDTGVYSCTAQNTAGSISANATLTVLETPSFLRPLLDRTVTKGETAVLQCIAGGSPPPRLNWTKDDSPLVVTERHFFAASNQLLIIVDTDVEDAGKYTCEMSNTLGTERGNIRLNVIPTPTCDSPQNITPALDDDGWATVGIVIIAVVCCVVGTSLVWVVIIYHTRRRNEDCSITNTDETNLPADIPSYLSSQGTLAERQDGYGSSENGSHHQFLTSSVGGYFLQQRDSNGICHLDNGSETDLDGVADPFLCHYLGTSGTMYLKGNTYSSETFEACSPSCSPDQRTASLDPYESGYLKKKECCQYSLPLEDPFDQCIGVIGMQATGSKLINSIYTQNEGTGLKSRSLNSDKLDLNRSLEPSSIISNSTFMGTFGKPVWRPQLDSLSGRRQPAASCQPKTSHNNPHSSLDFDPEADEDGRERTVSRGQNSIYNYKQSFENFRTFNFQSCDLDT", "length": 1099, "header": "tr|A0A8V0YV24-1|A0A8V0YV24_CHICK Computationally mapped isoform of Leucine rich repeats and immunoglobulin like domains 3 OS=Gallus gallus OX=9031 GN=LRIG3 PE=4 SV=1 CANONICAL=A0A8V0YGW9-1" }, "locus": { "chromosome": "1", "start_pos": 31906613, "end_pos": 31863658, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034229.1", "url": "https://www.ensembl.org/id/ENSGALT00010034229.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020111.1", "url": "https://www.ensembl.org/id/ENSGALP00010020111.1" } ] } }, { "isoform_ac": "A0A8V0YV35-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGW9/entry#A0A8V0YV35-1", "sequence": { "sequence": "MDLSHNKLSSIKANFLDHLHSLREVKLNNNELEIIPNLGPVSANITLLSLTSNKIANILSEHLKPFQSLETLDLSNNNISELKMSSFPSLQLKYLYINSNRITSMEPGTFDNLSTTLQVLKLNRNKISAIPQKMFKLSHLQHLELNRNKIKKIDGLTFQGLPALKSLKLQRNGITRLMDGAFWGLTNMEVLQLDHNNLTEVTKGWLYGLLMLQQLHLSQNAISRISPDAWEFCQKLSELDLTFNHLARLDDSSFAGLSVLVGLYIGSNKVNYIADCAFRGLSSLQTLDLKNNEISWTIEDMNGAFSGLDKLRNLILQGNRIRSITKKAFSGLDALEHLDLSNNAIMSVQGNAFSQMKKLKELHLNTSSLLCDCQLKWLPQWVSENNFQNFVNASCAHPQLLKGRSIFAVSLDAFVCDDFPKPQITVQPETQSAIKGSNLSFVCSAASSSDSPMTFAWKKDNELLHDAEMENYAHLRAQGGEVMEYTTILRLRNVEFSSEGKYQCVISNHFGSSYSIKAKLTVNMLPSFTKIPMDLTIRAGAMARLECAAVGHPVPQIAWQKDGGTDFPAARKRRMHVMPEDDVFFIVDVKIEDTGVYSCTAQNTAGSISANATLTVLETPSFLRPLLDRTVTKGETAVLQCIAGGSPPPRLNWTKDDSPLVVTERHFFAASNQLLIIVDTDVEDAGKYTCEMSNTLGTERGNIRLNVIPTPTCDSPQNITPALDDDGWATVGIVIIAVVCCVVGTSLVWVVIIYHTRRRNEDCSITNTDETNLPADIPSYLSSQGTLAERQDGYGSSENGSHHQFLTSSVGGYFLQQRDSNGICHLDNGSETDLDGVADPFLCHYLGTSGTMYLKGNTYSSETFEACSPSCSPDQRTASLDPYESGYLKKKECCQYSLPLEDPFDQCIGVIGMQATGSKLINSIYTQNEGTGLKSRSLNSDKLDLNRSLEPSSIISNSTFMGTFGKPVWRPQLDSLSGRRQPAASCQPKTSHNNPHSSLDFDPEADEDGRERTVSRGQNSIYNYKQSFENFRTFNFQSCDLDT", "length": 1043, "header": "tr|A0A8V0YV35-1|A0A8V0YV35_CHICK Computationally mapped isoform of Leucine rich repeats and immunoglobulin like domains 3 OS=Gallus gallus OX=9031 GN=LRIG3 PE=4 SV=1 CANONICAL=A0A8V0YGW9-1" }, "locus": { "chromosome": "1", "start_pos": 31939333, "end_pos": 31863658, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034248.1", "url": "https://www.ensembl.org/id/ENSGALT00010034248.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020121.1", "url": "https://www.ensembl.org/id/ENSGALP00010020121.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 782, "start_aa": "Thr", "end_pos": 782, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr782", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:417813", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417813", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGW9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGW9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1008, "end_pos": 1010, "annotation": "n_glycosylation_sequon" }, { "start_pos": 100, "end_pos": 102, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1019, "end_pos": 1021, "annotation": 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"http://www.pantherdb.org/panther/family.do?clsAccession=PTHR35001", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR35001:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR35001:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YGX0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGX0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YGX0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGX0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YGX6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGX6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YGX6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGX6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHV1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHV1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHV1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHV1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHV6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHV6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHV6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHV6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "KERKGKERKGKERKGKERKGKERKGKERKGKEKKGKERKGWERKGKEKVGKERKKKGGKGKGGKGKGGKGKVGKGKERLGKERKGWERKGKKGKERKGKERKGWERKGKERVGKRGKGKGGKGKERVGKERKGKERKGKERKGKERKGKERKGKERKGKERKGKERKGKERKGKGGKGKERQGWERQGWERKGKERKGKERKGKERNGKERVGKGGKGWERKGKERKGWERVGKGGKGWERKGKERKGKERKGKERKGKERKGKGGKGKGGKGKGRNGKGGKGKERKGKERKGKERKGKERKGKERKGKERKGKESVGKERVGKERKGKESVGKERVGKERKGWERKGKERKGKERVGKERKGKRGKGKGGKGKERNRKRGKGKKRVGNKRMGKERAGKERKGWERKGWERKGKVGKGKGGKGKERKEWERKGWERKGKGGKGKERKGKERKGKERKGWERKGKGGKGWERKGKERKGKERKGKERKGKERKGKERKGKERKGKGGKGKERKGKGKERKGKERMGKERVGKERKGKERKGKERKGKERKGKVRKGKERKGKERKGKGGKGKESVGKERVGKERKGKERVGKERVGKERKGWERKGKGRKGKERKGWERKGKERKGKKRKGKERNRKRGKGKKRLGKKRAGKERKGWEIKRVGKERVGKGGKGKERKGWERKGKGGKGKGGKGKGGKGKGGKRKGKERKGWERKGKERKGKEKERKEWE", "length": 728, "header": "tr|A0A8V0YGX6-1|A0A8V0YGX6_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0YGX6-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YGX0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGX6/entry#A0A8V0YGX0-1", "sequence": { "sequence": "KKKGGKGKGGKGKGGKGKVGKGKERLGKERKGWERKGKKGKERKGKERKGWERKGKERVGKRGKGKGGKGKERVGKERKGKERKGKERKGKERKGKERKGKERKGKERKGKERKGKERKGKGGKGKERQGWERQGWERKGKERKGKERKGKERNGKERVGKGGKGWERKGKERKGWERVGKGGKGWERKGKERKGKERKGKERKGKERKGKGGKGKGGKGKGRNGKGGKGKERKGKERKGKERKGKERKGKERKGKERKGKESVGKERVGKERKGKESVGKERVGKERKGWERKGKERKGKERVGKERKGKRGKGKGGKGKERNRKRGKGKKRVGNKRMGKERAGKERKGWERKGWERKGKGGKGKKRKGKGGKGKERVGKERKGKGGKEKERKGKEKKRKGKERKGKERMGKERVGKERKGKERKGKERKGKERKGKERKGKGGKGKGGKGKERVGKERKG", "length": 462, "header": "tr|A0A8V0YGX0-1|A0A8V0YGX6_CHICK Computationally mapped isoform of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0YGX6-1" }, "locus": { "chromosome": "W", "start_pos": 7382691, "end_pos": 7379250, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031123.1", "url": "https://www.ensembl.org/id/ENSGALT00010031123.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018117.1", "url": "https://www.ensembl.org/id/ENSGALP00010018117.1" } ] } }, { "isoform_ac": "A0A8V0YGX6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGX6/entry#A0A8V0YGX6-1", "sequence": { "sequence": "KERKGKERKGKERKGKERKGKERKGKERKGKEKKGKERKGWERKGKEKVGKERKKKGGKGKGGKGKGGKGKVGKGKERLGKERKGWERKGKKGKERKGKERKGWERKGKERVGKRGKGKGGKGKERVGKERKGKERKGKERKGKERKGKERKGKERKGKERKGKERKGKERKGKGGKGKERQGWERQGWERKGKERKGKERKGKERNGKERVGKGGKGWERKGKERKGWERVGKGGKGWERKGKERKGKERKGKERKGKERKGKGGKGKGGKGKGRNGKGGKGKERKGKERKGKERKGKERKGKERKGKERKGKESVGKERVGKERKGKESVGKERVGKERKGWERKGKERKGKERVGKERKGKRGKGKGGKGKERNRKRGKGKKRVGNKRMGKERAGKERKGWERKGWERKGKVGKGKGGKGKERKEWERKGWERKGKGGKGKERKGKERKGKERKGWERKGKGGKGWERKGKERKGKERKGKERKGKERKGKERKGKERKGKGGKGKERKGKGKERKGKERMGKERVGKERKGKERKGKERKGKERKGKVRKGKERKGKERKGKGGKGKESVGKERVGKERKGKERVGKERVGKERKGWERKGKGRKGKERKGWERKGKERKGKKRKGKERNRKRGKGKKRLGKKRAGKERKGWEIKRVGKERVGKGGKGKERKGWERKGKGGKGKGGKGKGGKGKGGKRKGKERKGWERKGKERKGKEKERKEWE", "length": 728, "header": "tr|A0A8V0YGX6-1|A0A8V0YGX6_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0YGX6-1" }, "locus": { "chromosome": "W", "start_pos": 7383055, "end_pos": 7378989, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031129.1", "url": "https://www.ensembl.org/id/ENSGALT00010031129.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018122.1", "url": "https://www.ensembl.org/id/ENSGALP00010018122.1" } ] } }, { "isoform_ac": "A0A8V0YHV1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGX6/entry#A0A8V0YHV1-1", "sequence": { "sequence": "KGGKGKGGKGKGGKGKVGKGKERLGKERKGWERKGKKGKERKGKERKGWERKGKERVGKRGKGKGGKGKERVGKERKGKERKGKERKGKERKGKERKGKERKGKERKGKERKGKERKGKGGKGKERQGWERQGWERKGKERKGKERKGKERNGKERVGKGGKGWERKGKERKGWERVGKGGKGWERKGKERKGKERKGKERKGKERKGKGGKGKGGKGKGRNGKGGKGKERKGKERKGKERKGKERKGKERKGKERKGKESVGKERVGKERKGKESVGKERVGKERKGWERKGKERKGKERVGKERKGKRGKGKGGKGKERNRKRGKGKKRVGNKRMGKERAGKERKGWERKGWERKGKGGKGKERVGKERKGWERKGKERKRKGKGGKGKERVGKERVGKDTKGKERVGKERVRKERKGWERKGKGRKGKERKGWERKGKERKGKKKERKGKERKGKDGKGKGGKGKERKGKERKGKERKGKERKGKERKGKERKGKERKGWERKGKCGKGKGGKGKERKGKGGKGKGGKGKERVGKERKG", "length": 542, "header": "tr|A0A8V0YHV1-1|A0A8V0YHV1_CHICK Computationally mapped isoform of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0YGX6-1" }, "locus": { "chromosome": "W", "start_pos": 7382691, "end_pos": 7379256, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031121.1", "url": "https://www.ensembl.org/id/ENSGALT00010031121.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018115.1", "url": "https://www.ensembl.org/id/ENSGALP00010018115.1" } ] } }, { "isoform_ac": "A0A8V0YHV6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGX6/entry#A0A8V0YHV6-1", "sequence": { "sequence": "RKGWERKGRERKGKGKKKKGGKGKGGKGKGGKGKVGKGKERLGKERKGWERKGKKGKERKGKERKGWERKGKERVGKRGKGKGGKGKERVGKERKGKERKGKERKGKERKGKERKGKERKGKERKGKERKGKERKGKGGKGKERQGWERQGWERKGKERKGKERKGKERNGKERVGKGGKGWERKGKERKGWERVGKGGKGWERKGKERKGKERKGKERKGKERKGKGGKGKGGKGKGRNGKGGKGKERKGKERKGKERKGKERKGKERKGKERKGKESVGKERVGKERKGKESVGKERVGKERKGWERKGKERKGKERVGKERKGKRGKGKGGKGKERNRKRGKGKKRVGNKRMGKERAGKERKGWERKGWERKGKERKGKERKGKERKGWERKGWERKGWERKGKERKGWEKKRLGKERKGWERKGKGRKGKERVGKKRKGKERKKKGKERKGIESVVKEREGWERKGRERKGKERVGKERVGKERVGKGGKGKESKGKERKGKKKERKGKERKGKDGKGKGGKGKERKGKERKGKERKGKERKGKERKGWERKGKGGKGKGGKGKGGKGKGGKRKGKERKGWERKGKERKGKEKERKEWE", "length": 603, "header": "tr|A0A8V0YHV6-1|A0A8V0YHV6_CHICK Computationally mapped isoform of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0YGX6-1" }, "locus": { "chromosome": "W", "start_pos": 7383055, "end_pos": 7379202, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031126.1", "url": "https://www.ensembl.org/id/ENSGALT00010031126.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018120.1", "url": "https://www.ensembl.org/id/ENSGALP00010018120.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YGX7-1", "uniprot_ac": "A0A8V0YGX7", "uniprot_id": "A0A8V0YGX7_CHICK", "mass": { "chemical_mass": 26885.0, "monoisotopic_mass": 26885.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Uncharacterized protein", "type": "synonym", "evidence": [ { "id": "A0A8V0YGX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGX7/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGX7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGX7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGX7", "locus": {} } ], "crossref": [ { "id": "A0A8V0YGX7", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YGX7", "database": "AlphaFoldDB", "categories": [] }, { "id": "A0A8V0YGX7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGX7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YGX7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGX7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTNVDLLCEDGSIVICIKNNDVDLGGPAPGRRAPIGGNESEIQLRLLLSVQRLLQNKFYKLPILTLNEDSEELVLRNDAVRLDVIGANVQVLSRPHRETCARVAPLRDLKGHSFVREDRRVVIDVLHGHLDREELQRVGEQQLEGERAGAGASAHLLPIEPLGDNEAAAAALQAKVLPAGRRGDARPASRELRRGQPRVLRHVGHHRAALALLGHGVADGLAANARHAQQTPNSTTTTIRSTKARTGA", "length": 248, "header": "tr|A0A8V0YGX7-1|A0A8V0YGX7_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0YGX7-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YGX7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGX7/entry#A0A8V0YGX7-1", "sequence": { "sequence": "MTNVDLLCEDGSIVICIKNNDVDLGGPAPGRRAPIGGNESEIQLRLLLSVQRLLQNKFYKLPILTLNEDSEELVLRNDAVRLDVIGANVQVLSRPHRETCARVAPLRDLKGHSFVREDRRVVIDVLHGHLDREELQRVGEQQLEGERAGAGASAHLLPIEPLGDNEAAAAALQAKVLPAGRRGDARPASRELRRGQPRVLRHVGHHRAALALLGHGVADGLAANARHAQQTPNSTTTTIRSTKARTGA", "length": 248, "header": "tr|A0A8V0YGX7-1|A0A8V0YGX7_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0YGX7-1" }, "locus": { "chromosome": "13", "start_pos": 1282254, "end_pos": 1280920, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026775.1", "url": "https://www.ensembl.org/id/ENSGALT00010026775.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015265.1", "url": "https://www.ensembl.org/id/ENSGALP00010015265.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], 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"ac": "XP_015131455", "name": "nuclear pore complex protein Nup153 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015131455" }, "gene_names": [ { "name": "NUP153", "type": "recommended", "evidence": [ { "id": "A0A8V0YGY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGY2" } ] }, { "name": "NUP153", "type": "synonym", "evidence": [ { "id": "XP_015131455", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015131455" } ] } ], "protein_names": [ { "name": "Nuclear pore complex protein Nup153", "type": "recommended", "evidence": [ { "id": "A0A8V0YGY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGY2/entry#names_and_taxonomy" } ] }, { "name": "153 kDa nucleoporin", "type": "synonym", "evidence": [ { "id": "A0A8V0YGY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGY2/entry#names_and_taxonomy" } ] }, { "name": "Nucleoporin Nup153", "type": "synonym", "evidence": [ { "id": "A0A8V0YGY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGY2/entry#names_and_taxonomy" } ] }, { "name": "nuclear pore complex protein Nup153 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015131455", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015131455" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052533.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015131455.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015131455", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015131455" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGY2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGY2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "NUP153", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGY2", "locus": { "chromosome": "2", "start_pos": 61770870, "end_pos": 61817969, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010011210", "url": "https://www.ensembl.org/id/ENSGALG00010011210" } ] } } ], "crossref": [ { "id": "420848", "url": "https://www.ncbi.nlm.nih.gov/gene/420848", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": 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{ "id": "R-GGA-4551638", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-4551638", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-4615885", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-4615885", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_015131455", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015131455", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YC90", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC90", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YC90-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC90-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YGY2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGY2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YGY2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGY2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASGGGGGTGGGAGGGGKIRTRRYHLGAAKPPYGRSRQQGIISRMTESVKNIVPGWLQKYFNKSEDECVDTNESTNQEENPVNYHHDYGDEDTIMTDGRVTPEPAGINLEEPSTSRSALNFSVVLTRPSLHRSHLNCTVLDSTVPPCQPSTSSTLGIGNPGLSLVKEIKDSTSQHDDDNISTTSGFSSRASDKDIAVSKNNSAPLLWSTEAERSHSLSQHSASSSKKPAFNLSAFGALSPSLGNTSVFKTSQLGDSPFYPGKTTYGGAAAAARQTKVRIAPYQTPVRRQMKAKQANVQSYGVTSSTARRILQSLEKMSSPLADAKRIPSSVTSPLSSPVDRSVLGITGFHSTRKQMESQHPPVQKLVTPKAISLSGSRTQYFKPSLTPSADSSKIHQRVDTKHKEMKEKSLPEEQRVEPSESNLTYPKFSTPASNGLSSGVSGGGKMRRERGVHYVSKSGQEQEVEEPVLPKISLPISTASLAPFNFSFLTSSTVSSPPSTVSTSVMNKVQPTSNVGSPVFRFSSPIVKSTEAEVLPPLSQIGFTFSVPVVKSAERSGSSDTPVTSLLTRDTTTVNSISNKKEEKEEYDGPFKPAKVLKEGSVLDILRSPGFTSVKTHSSASAQPITSTAVYTRPAISSFSAGKETPKQASSYWQSDPCDPCSQNKAADSKCVTCQAAKVSTAESTKQTTSSSPSGSTKAAAPPVGMLGFGDKFKAAPGTWDCDTCLVQNKPEATKCVACETPKPGMGVMPTLALPVTTESSVTVTSSSSSTDTTVTLGFGDKFKKPKGSWDCATCFVSNKAEDSKCVACQSEKPGSSVPVTSSSASAFAAPSGDLLDLDKFKKPEGSWDCEVCLVQNKAEATKCVACESAKPGTKAEFKGFDASAVSTNAALPSFTFGVQSSSSDSQTSSVTGSFKFGEQGGFKFGIASESASSNTAPGGFKFPSSSGNFKFGVSSSDSKPEESKKEDKSNNFTFGLPSTSSPAPLTFQFGTASLGQQEKKEQQPVLGGFSFGSSSTSVTTSENKTGVAGFTFGTVAENEVASASFAFKKSDEKKDETPSTKAGFSFGNVESAPASQFVLGRTEEKQDSVSSAAPLLFGKKADNEESKAQPVFSVGQSEHTKEESTAKPMFNFSFVKPSEKENEQAKPTFSFGAQASTSDQGAAKPSFSFLSSSSSSTAIPATSANSSSVFGSITSSSNPAPVPTPFVFGQASNTVSSTAFGNSAESTASQSFGFSQESKPATTSSTTGAAVAPFVFGSGASSSSAASSGFTFGATATSSSTGSSSSFVFGSGSSAPAAGPAFGAGQLPAFGQSQGSGQPNAPSFGSLSTTLFSAGSQPAPPAFGSVTSSTQPPVFGQQSSQQPGFGSGTSSTGPVFQFGSSTSNFNFTSNPEVFTFGANPPAPAASVQPSGSSGFSFSQPPAFTVGTNGKNIFSASGSSVSVRKIKTAVRRRK", "length": 1455, "header": "tr|A0A8V0YGY2-1|A0A8V0YGY2_CHICK Isoform 1 of Nuclear pore complex protein Nup153 OS=Gallus gallus OX=9031 GN=NUP153 PE=1 SV=1 CANONICAL=A0A8V0YGY2-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YC90-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGY2/entry#A0A8V0YC90-1", "sequence": { "sequence": "MREGLQGIISRMTESVKNIVPGWLQKYFNKSEDECVDTNESTNQEENPVNYHHDYGDEDTIMTDGRVTPEPAGINLEEPSTSRSALNFSVVLTRPSLHRSHLNCTVLDSTVPPCQPSTSSTLGIGNPGLSLVKEIKDSTSQHDDDNISTTSGFSSRASDKDIAVSKNNSAPLLWSTEAERSHSLSQHSASSSKKPAFNLSAFGALSPSLGNTSVFKTSQLGDSPFYPGKTTYGGAAAAARQTKVRIAPYQTPVRRQMKAKQANVQSYGVTSSTARRILQSLEKMSSPLADAKRIPSSVTSPLSSPVDRSVLGITGFHSTRKQMESQHPPVQKLVTPKAISLSGSRTQYFKPSLTPSADSSKIHQRVDTKHKEMKEKSLPEEQRVEPSESNLTYPKFSTPASNGLSSGVSGGGKMRRERGVHYVSKSGQEQEVEEPVLPKISLPISTASLAPFNFSFLTSSTVSSPPSTVSTSVMNKVQPTSNVGSPVFRFSSPIVKSTEAEVLPPLSQIGFTFSVPVVKSAERSGSSDTPVTSLLTRDTTTVNSISNKKEEKEEYDGPFKPAKVLKEGSVLDILRSPGFTSVKTHSSASAQPITSTAVYTRPAISSFSAGKETPKQASSYWQSDPCDPCSQNKAADSKCVTCQAAKVSTAESTKQTTSSSPSGSTKAAAPPVGMLGFGDKFKAAPGTWDCDTCLVQNKPEATKCVACETPKPGMGVMPTLALPVTTESSVTVTSSSSSTDTTVTLGFGDKFKKPKGSWDCATCFVSNKAEDSKCVACQSEKPGSSVPVTSSSASAFAAPSGDLLDLDKFKKPEGSWDCEVCLVQNKAEATKCVACESAKPGTKAEFKGFDASAVSTNAALPSFTFGVQSSSSDSQTSSVTGSFKFGEQGGFKFGIASESASSNTAPGGFKFPSSSGNFKFGVSSSDSKPEESKKEDKSNNFTFGLPSTSSPAPLTFQFGTASLGQQEKKEQQPVLGGFSFGSSSTSVTTSENKTGVAGFTFGTVAENEVASASFAFKKSDEKKDETPSTKAGFSFGNVESAPASQFVLGRTEEKQDSVSSAAPLLFGKKADNEESKAQPVFSVGQSEHTKEESTAKPMFNFSFVKPSEKENEQAKPTFSFGAQASTSDQGAAKPSFSFLSSSSSSTAIPATSANSSSVFGSITSSSNPAPVPTPFVFGQASNTVSSTAFGNSAESTASQSFGFSQESKPATTSSTTGAAVAPFVFGSGASSSSAASSGFTFGATATSSSTGSSSSFVFGSGSSAPAAGPAFGAGQLPAFGQSQGSGQPNAPSFGSLSTTLFSAGSQPAPPAFGSVTSSTQPPVFGQQSSQQPGFGSGTSSTGPVFQFGSSTSNFNFTSNPEVFTFGANPPAPAASVQPSGSSGFSFSQPPAFTVGTNGKNIFSASGSSVSVRKIKTAVRRRK", "length": 1422, "header": "tr|A0A8V0YC90-1|A0A8V0YC90_CHICK Computationally mapped isoform of Nuclear pore complex protein Nup153 OS=Gallus gallus OX=9031 GN=NUP153 PE=1 SV=1 CANONICAL=A0A8V0YGY2-1" }, "locus": { "chromosome": "2", "start_pos": 61803813, "end_pos": 61771874, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026783.1", "url": "https://www.ensembl.org/id/ENSGALT00010026783.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015267.1", "url": "https://www.ensembl.org/id/ENSGALP00010015267.1" } ] } }, { "isoform_ac": "A0A8V0YGY2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGY2/entry#A0A8V0YGY2-1", "sequence": { "sequence": "MASGGGGGTGGGAGGGGKIRTRRYHLGAAKPPYGRSRQQGIISRMTESVKNIVPGWLQKYFNKSEDECVDTNESTNQEENPVNYHHDYGDEDTIMTDGRVTPEPAGINLEEPSTSRSALNFSVVLTRPSLHRSHLNCTVLDSTVPPCQPSTSSTLGIGNPGLSLVKEIKDSTSQHDDDNISTTSGFSSRASDKDIAVSKNNSAPLLWSTEAERSHSLSQHSASSSKKPAFNLSAFGALSPSLGNTSVFKTSQLGDSPFYPGKTTYGGAAAAARQTKVRIAPYQTPVRRQMKAKQANVQSYGVTSSTARRILQSLEKMSSPLADAKRIPSSVTSPLSSPVDRSVLGITGFHSTRKQMESQHPPVQKLVTPKAISLSGSRTQYFKPSLTPSADSSKIHQRVDTKHKEMKEKSLPEEQRVEPSESNLTYPKFSTPASNGLSSGVSGGGKMRRERGVHYVSKSGQEQEVEEPVLPKISLPISTASLAPFNFSFLTSSTVSSPPSTVSTSVMNKVQPTSNVGSPVFRFSSPIVKSTEAEVLPPLSQIGFTFSVPVVKSAERSGSSDTPVTSLLTRDTTTVNSISNKKEEKEEYDGPFKPAKVLKEGSVLDILRSPGFTSVKTHSSASAQPITSTAVYTRPAISSFSAGKETPKQASSYWQSDPCDPCSQNKAADSKCVTCQAAKVSTAESTKQTTSSSPSGSTKAAAPPVGMLGFGDKFKAAPGTWDCDTCLVQNKPEATKCVACETPKPGMGVMPTLALPVTTESSVTVTSSSSSTDTTVTLGFGDKFKKPKGSWDCATCFVSNKAEDSKCVACQSEKPGSSVPVTSSSASAFAAPSGDLLDLDKFKKPEGSWDCEVCLVQNKAEATKCVACESAKPGTKAEFKGFDASAVSTNAALPSFTFGVQSSSSDSQTSSVTGSFKFGEQGGFKFGIASESASSNTAPGGFKFPSSSGNFKFGVSSSDSKPEESKKEDKSNNFTFGLPSTSSPAPLTFQFGTASLGQQEKKEQQPVLGGFSFGSSSTSVTTSENKTGVAGFTFGTVAENEVASASFAFKKSDEKKDETPSTKAGFSFGNVESAPASQFVLGRTEEKQDSVSSAAPLLFGKKADNEESKAQPVFSVGQSEHTKEESTAKPMFNFSFVKPSEKENEQAKPTFSFGAQASTSDQGAAKPSFSFLSSSSSSTAIPATSANSSSVFGSITSSSNPAPVPTPFVFGQASNTVSSTAFGNSAESTASQSFGFSQESKPATTSSTTGAAVAPFVFGSGASSSSAASSGFTFGATATSSSTGSSSSFVFGSGSSAPAAGPAFGAGQLPAFGQSQGSGQPNAPSFGSLSTTLFSAGSQPAPPAFGSVTSSTQPPVFGQQSSQQPGFGSGTSSTGPVFQFGSSTSNFNFTSNPEVFTFGANPPAPAASVQPSGSSGFSFSQPPAFTVGTNGKNIFSASGSSVSVRKIKTAVRRRK", "length": 1455, "header": "tr|A0A8V0YGY2-1|A0A8V0YGY2_CHICK Isoform 1 of Nuclear pore complex protein Nup153 OS=Gallus gallus OX=9031 GN=NUP153 PE=1 SV=1 CANONICAL=A0A8V0YGY2-1" }, "locus": { "chromosome": "2", "start_pos": 61817897, "end_pos": 61771874, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026787.1", "url": "https://www.ensembl.org/id/ENSGALT00010026787.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015270.1", "url": "https://www.ensembl.org/id/ENSGALP00010015270.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1206, "start_aa": "Thr", "end_pos": 1206, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1206", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:420848", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420848", "resource": "KEGG Pathway" }, { "id": "R-GGA-159227", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-159227", "resource": "Reactome", "description": "Transport of the SLBP independent Mature mRNA" }, { "id": "R-GGA-159230", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-159230", "resource": "Reactome", "description": "Transport of the SLBP Dependant Mature mRNA" }, { "id": "R-GGA-159231", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-159231", "resource": "Reactome", "description": "Transport of Mature mRNA Derived from an Intronless Transcript" }, { "id": "R-GGA-159236", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-159236", "resource": "Reactome", "description": "Transport of Mature mRNA derived from an Intron-Containing Transcript" }, { "id": "R-GGA-1855170", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1855170", "resource": "Reactome", "description": "IPs transport between nucleus and cytosol" }, { "id": "R-GGA-1855196", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1855196", "resource": "Reactome", "description": "IP3 and IP4 transport between cytosol and nucleus" }, { "id": "R-GGA-1855229", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1855229", "resource": "Reactome", "description": "IP6 and IP7 transport between cytosol and nucleus" }, { "id": "R-GGA-191859", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-191859", "resource": "Reactome", "description": "snRNP Assembly" }, { "id": "R-GGA-3108214", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3108214", "resource": "Reactome", "description": "SUMOylation of DNA damage response and repair proteins" }, { "id": "R-GGA-3232142", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3232142", "resource": "Reactome", "description": "SUMOylation of ubiquitinylation proteins" }, { "id": "R-GGA-3301854", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3301854", "resource": "Reactome", "description": "Nuclear Pore Complex (NPC) Disassembly" }, { "id": "R-GGA-4085377", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-4085377", "resource": "Reactome", "description": "SUMOylation of SUMOylation proteins" }, { "id": "R-GGA-4551638", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-4551638", "resource": "Reactome", "description": "SUMOylation of chromatin organization proteins" }, { "id": "R-GGA-4615885", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-4615885", "resource": "Reactome", "description": "SUMOylation of DNA replication proteins" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0R4IVZ0-1", "protein_name": "Nuclear pore complex protein Nup153", "gene_name": "nup153", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAATGGGKIRSRRHHIASKPYAKGKQQPGLITRVTDTVKSIVPSWLQKYFRNGEGPEGGASAAGVEHNNMTPPPNGSDEAPLRDGRDSPEPSTSNTEPSTSRASLNFQEALSRPPLNRTHLQFPSLDGSPALGGSSSLFSQPSTSTAPFSGSPFAVTSNFSLVKEIKDSSSQHEDDNISTTSGFSSRASDKDVPTSKTVPLLWSPETERTHSGSQTAHSGLKKPAFNLSVFGTSSSSVLNSSVLNSSQLGDSPFYPGKTTYGGASAMRTARSRPATPYQPPVRRQIKAKPTGAQPCGVTSATARRILQSLERMSSPLADAKRIPSTVSSPLSASLNHTDLDISNYQAKRKRLEPSVPPVQKLVVPAAAAVSGNRSISFRPSLTPGGVSRGVEKTSRETPVRQSPPISEPAQAPPPSTSTLSYPLSSTPAANSAALGGGKMKRERAIRPSSKRPDDEVAEEPDLPPASLPSNFTLPTFTFSTPPPTSSLKSSTAPLITVSEEPAANKQPAAPSTPPSAPFTFSSPIVKATAASPPSFSPSSGFTFSAPTMKMGPSFSNGKIVPSVAPVKSVVIEEKEFEGPFKPAKVLKQGSVLDILKGPGFASPSQNSTDKPLQSTSTTTSSPFSGFGDKFRPPAGSWNCGTCMLQNKPSDKKCVACLAPQPNTDSSKSDSKPAEAPASISSLFAPPAGSWECDTCLVSNKPDAVKCVACDTAKPGTGVKSSLTLLAASESSSSTTTTATTTAAALTSTGLLGLGDKFKKPEGAWDCDVCMVQNKAQDLKCVACLTAKPGAAAAPLSTPASAPVSSAAPLLGFGDKFKKPEGSWECDVCCVQNKADDQQCVACQSAKPGAKIESKGFSSSFGVQSNSTDSNTSGFKFGTGSTDSSSSSAGLKFGGTFSDSSTTGGIKFGFGLSSTSSEGFKFGGSSSDAGGAKLSSTLSESTATKESSTKSFAFGGSADDTLEKKSKTQESNTGFKFGGGSGMASGSENSSFLFGAKPSEKGSSNPSFSFPVPQSKVEKDAPSETPPVSNTTTTTTAANALPVFGKSLVAESSAPKFGEPATKEQTLVTSTFTFGKPEEKKDTSAPSSTFLFGSSKEAEKPTPNLGFAFSEPDPPKDFPKPALTFGKPAESTEPPKPSFGFGQSLTETSAPKPSFGFMANSTSSTPASSSSTPSLFGTPTTSSLAPTPAPTSTFVFGQNSSSELNVGKTFVFGQQQQDSQPAPPAAPSAAPAQPFQFGSGSNSSTPSFTFGAAASSTPASAAPAPSANPSPFVFSSAAPSSGFGSGQTPIFGQSASQPSAPAFGSAAPSFSASATPASTFGAKPSSAPVFGQQANAAPTFGSTAASTGQGGFQFGSTGGFGASATSNSVFNFGGGSAAPAASPAMPALNPPAGGGFGFSPTPAFNIGSAKSSFTASPAGQNSIAGRKIKTAVRRRK", "length": 1436 }, "evidence": [ { "id": "A0A8V0YGY2", "url": "https://omabrowser.org/oma/group/A0A8V0YGY2/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "E9Q3G8-1", "protein_name": "Nuclear pore complex protein Nup153", "gene_name": "Nup153", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASEAGGIGGGGGGGKIRTRRCHQGPVKPYQQGRPQHQGILSRVTESVKNIVPGWLQRYFNKSENACSCSPDADEVPPWPENREDEHAIYADENTNTDDGRITPDPAGSNTEEPSTTSTASNYPDVLTRPSLHRSHLNFSVLESPALHCQPSTSSAFPIGSSGFSLVKEIKDSTSQHDDDNISTTSGFSSRASEKDIAVSKNTSLPPLWSPEAERSHSLSQHTAISSKKPAFNLSAFGTLSTSLGNSSILKTSQLGDSPFYPGKTTYGGAAAAVRQNKVRSTPYQAPVRRQMKAKQLNAQSYGVTSSTARRILQSLEKMSSPLADAKRIPSAVSSPLNSPLDRSGIDNTVFQAKKEKVDSQYPPVQRLMTPKPVSIATNRTVYFKPSLTPSGDLRKTNQRIDKKNSTVDEKSISRQNREQESGFSYPNFSIPAANGLSSGVGGGGGKMRRERTHFVAPKPPENEEVEAPLLPQISLPISSSSLPTFSFSSPVTSASPSPVSSSQPLPNKVQMTSLGSTGSPVFTFSSPIVKSTQAAVLPPASIGFTFSVPLAKTEFSGSNSSSETVLSSSAQDITAVNSSSYKKRSAPCEDPFTPAKILREGSVLDILKTPGFASPKVDSPALQPTTTSSIVYTRPAISTFSSSGIEYGESLKAGSSWQCDTCLLQNKVTDNKCIACQAAKLPLKETAKQTGTGTPSKSDKPASTSGTGFGDKFKPAIGTWDCDTCLVQNKPEAVKCVACETPKPGTGVKRALTLTVASESPVTASSSTTVTTGTLGFGDKFKRPVGSWECPVCCVCNKAEDNRCVSCTSEKPGLVSASSSSPAPVSLSSGGCLGLDKFKKPEGSWDCEVCLVQNKADSAKCIACESAKPGTKSEFKGFGTSSSLNPAPSAFKFGIPSSSSGLSQTLTSTGNFKFGDQGGFKLGTSSDSGSTNTMNTNFKFSKPTGDFKFGVLSDSKPEEVKNDNKNDNFQFGSSSGLTNPASSAPFQFGVSTLGQQEKKEELPKSSPAGFSFGAGVNNPPNAAIDTTATSENKSGFNFGTLDTKSVSVTPFTYKTTEAKKEDAPATKGGFTFGKVGSSSLPSSSMFVLGRTEEKQQEPVTSTSLVFGKKADSEEPKCQPVFSFGNSEQTKDESSKPTFSFSVAKPSGKESEQLAKATFAFGNQTNTTTDQGAAKPVFSFLNSSSSSSSAPATSSSGGIFGSSTSSSNPPVAAFVFGQASNPVSSSAFGNAAESSTSQSLLFPQESEPATTSSTAPAASPFVFGTGASSNSVSSGFTFGATTTSSSSGSSFVFGTGHSAPSASPAFGANQTPTFGQSQGASQPNPPSFGSISSSTALFSAGSQPVPPPIFGTVSSSSQPPVFGQQPSQSAFGSGTANASSVFQFGSSTTNFNFTNNNPSGVFTFGASPSTPAASAQPSGSGVFSFSQSPASFTVGSNGKNMFSSSGTSVSGRKIKTAVRRKK", "length": 1462 }, "evidence": [ { "id": "A0A8V0YGY2", "url": "https://omabrowser.org/oma/group/A0A8V0YGY2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P49790-1", "protein_name": "Nuclear pore complex protein Nup153", "gene_name": "NUP153", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MASGAGGVGGGGGGKIRTRRCHQGPIKPYQQGRQQHQGILSRVTESVKNIVPGWLQRYFNKNEDVCSCSTDTSEVPRWPENKEDHLVYADEESSNITDGRITPEPAVSNTEEPSTTSTASNYPDVLTRPSLHRSHLNFSMLESPALHCQPSTSSAFPIGSSGFSLVKEIKDSTSQHDDDNISTTSGFSSRASDKDITVSKNTSLPPLWSPEAERSHSLSQHTATSSKKPAFNLSAFGTLSPSLGNSSILKTSQLGDSPFYPGKTTYGGAAAAVRQSKLRNTPYQAPVRRQMKAKQLSAQSYGVTSSTARRILQSLEKMSSPLADAKRIPSIVSSPLNSPLDRSGIDITDFQAKREKVDSQYPPVQRLMTPKPVSIATNRSVYFKPSLTPSGEFRKTNQRIDNKCSTGYEKNMTPGQNREQRESGFSYPNFSLPAANGLSSGVGGGGGKMRRERTRFVASKPLEEEEMEVPVLPKISLPITSSSLPTFNFSSPEITTSSPSPINSSQALTNKVQMTSPSSTGSPMFKFSSPIVKSTEANVLPPSSIGFTFSVPVAKTAELSGSSSTLEPIISSSAHHVTTVNSTNCKKTPPEDCEGPFRPAEILKEGSVLDILKSPGFASPKIDSVAAQPTATSPVVYTRPAISSFSSSGIGFGESLKAGSSWQCDTCLLQNKVTDNKCIACQAAKLSPRDTAKQTGIETPNKSGKTTLSASGTGFGDKFKPVIGTWDCDTCLVQNKPEAIKCVACETPKPGTCVKRALTLTVVSESAETMTASSSSCTVTTGTLGFGDKFKRPIGSWECSVCCVSNNAEDNKCVSCMSEKPGSSVPASSSSTVPVSLPSGGSLGLEKFKKPEGSWDCELCLVQNKADSTKCLACESAKPGTKSGFKGFDTSSSSSNSAASSSFKFGVSSSSSGPSQTLTSTGNFKFGDQGGFKIGVSSDSGSINPMSEGFKFSKPIGDFKFGVSSESKPEEVKKDSKNDNFKFGLSSGLSNPVSLTPFQFGVSNLGQEEKKEELPKSSSAGFSFGTGVINSTPAPANTIVTSENKSSFNLGTIETKSASVAPFTCKTSEAKKEEMPATKGGFSFGNVEPASLPSASVFVLGRTEEKQQEPVTSTSLVFGKKADNEEPKCQPVFSFGNSEQTKDENSSKSTFSFSMTKPSEKESEQPAKATFAFGAQTSTTADQGAAKPVFSFLNNSSSSSSTPATSAGGGIFGSSTSSSNPPVATFVFGQSSNPVSSSAFGNTAESSTSQSLLFSQDSKLATTSSTGTAVTPFVFGPGASSNNTTTSGFGFGATTTSSSAGSSFVFGTGPSAPSASPAFGANQTPTFGQSQGASQPNPPGFGSISSSTALFPTGSQPAPPTFGTVSSSSQPPVFGQQPSQSAFGSGTTPNSSSAFQFGSSTTNFNFTNNSPSGVFTFGANSSTPAASAQPSGSGGFPFNQSPAAFTVGSNGKNVFSSSGTSFSGRKIKTAVRRRK", "length": 1475 }, "evidence": [ { "id": "A0A8V0YGY2", "url": "https://omabrowser.org/oma/group/A0A8V0YGY2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P49791-1", "protein_name": "Nuclear pore complex protein Nup153", "gene_name": "Nup153", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASGAGGIGGGGGGGKIRTRRCHQGPVKPYQQGRPQHQGILSRVTESVKNIVPGWLQRYFNKSENACSCSVNADEVPRWPENREDEREIYVDENTNTDDGRTTPEPTGSNTEEPSTTSTASNYPDVLTRPSLHRSHLNFSVLESPALHCQPSTSSAFPIGSSGFSLVKEIKDSTSQHDDDNISTTSGFSSRASEKDIAVSKNTSLPPLWSPEAERSHSLSQHTAISSKKPAFNLSAFGTLSTSLGNSSILKTSQLGDSPFYPGKTTYGGAAAAVRQNKVRSTPYQAPVRRQMKAKQLNAQSYGVTSSTARRILQSLEKMSSPLADAKRIPSAVSSPLNSPLDRSGIDSTVFQAKKEKVDSQYPPVQRLMTPKPVSIATNRTVYFKPSLTPSGDLRKTNQRIDKKNSTVDEKNISRQNREQESGFSYPNFSIPAANGLSSGVGGGGGKMRRERTTHFVASKPSEEEEVEVPLLPQISLPISSSSLPTFNFSSPAISAASSSSVSPSQPLSNKVQMTSLGSTGNPVFTFSSPIVKSTQADVLPPASIGFTFSVPLAKTELSGPNSSSETVLSSSVTAQDNTVVNSSSSKKRSAPCEDPFTPAKILREGSVLDILKTPGFMSPKVDSPALQPTTTSSIVYTRPAISTFSSSGVEFGESLKAGSSWQCDTCLLQNKVTDNKCIACQAAKLPLKETAKQTGIGTPSKSDKPASTSGTGFGDKFKPAIGTWDCDTCLVQNKPEAVKCVACETPKPGTGVKRALPLTVASESPVTASSSTTVTTGTLGFGDKFKRPVGSWECPVCCVSNKAEDSRCVSCTSEKPGLVSASSSNSVPVSLPSGGCLGLDKFKKPEGSWDCEVCLVQNKADSTKCIACESAKPGTKSEFKGFGTSSSLNPAPSAFKFGIPSSSSGLSQTFTSTGNFKFGDQGGFKLGTSSDSGSTNTMNTNFKFPKPTGDFKFGVLPDSKPEEIKNDSKNDNFQFGPSSGLSNPASSAPFQFGVSTLGQQEKKEELPQSSSAGFSFGAGVANPSSAAIDTTVTSENKSGFNFGTIDTKSVSVTPFTYKTTEAKKEDASATKGGFTFGKVDSAALSSPSMFVLGRTEEKQQEPVTSTSLVFGKKADNEEPKCQPVFSFGNSEQTKDESSSKPTFSFSVAKPSVKESDQLAKATFAFGNQTNTTTDQGAAKPAFSFLNSSSSSSSTPATSSSASIFGSSTSSSSPPVAAFVFGQASNPVSSSAFGNSAESSTSQPLLFPQDGKPATTSSTASAAPPFVFGTGASSNSTVSSGFTFGATTTSSSSGSFFVFGTGHSAPSASPAFGANQTPTFGQSQGASQPNPPSFGSISSSTALFSAGSQPVPPPTFGTVSSSSQPPVFGQQPSQSAFGSGTANASSVFQFGSSTTNFNFTNNNPSGVFTFGASPSTPAAAAQPSGSGGFSFSQSPASFTVGSNGKNMFSSSGTSVSGRKIKTAVRRKK", "length": 1468 }, "evidence": [ { "id": "A0A8V0YGY2", "url": "https://omabrowser.org/oma/group/A0A8V0YGY2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9VXE6-1", "protein_name": "Nuclear pore complex protein Nup153", "gene_name": "Nup153", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MEDAQEQRESSQAELAKKHPLTPLKELPEESEEEEEEEDESSAGALRESDSNNSIMGKMKMRVSSILPASLSGWFSPSSKDGNDALSSPANLRQSQPRQSNGRLTTKRKRGRRRIMLAEVDADAADDLDDGSDAKGLNYEEVALADNIAEHDLAAEDEQTRRSEYNVFLLRKRAGAVAAAGGDEDEAEEDELEEDDEDGDEEDDDEEQENLQQSAAVQTKRRRLELETPVNLPNMRRLPLLSSTPAAPLAAATSSSSSQMYKGVSHIAPHRRNHLNLYGSQRQREPAYNFFTGNEAAEGSTGDLPHSIRRSLNIPFGGSSTATSYNNSLSSLPNHKRPSLIGKQTHRRDLTMDETGTGPAMSSEEHLNHLLRISRTNNNTSNNNNNNNNNNNVIETKTRRSELSAAAGGCGDSQSESDMNEYHDNGEGHDGLRPSHYNSNSNLEFYGNLQSSKSIFNRSNTAAQQSHRNSTWSLNSLTQRRRFNASIYGSTSALSDSRLLSGSASNSGSASASSSPFYQGRTTFGGNSGNNRLFSRSNLSSSAASSMLGLNSAGSSPAHQLHASMTGGIGYGMKAVDMRPSDSGSLAETSVGQGGSKKPGTGLSNTTMRILNLLESYSTPLIDAKRMGSSIKEHQSSRQQRQGTPATPYLRSTSASRNVSVPNHINELAELRSNKLLVPTMQQLLERRRLHRVTQNSRDVVHSQNVRAGGENNQEKPKPTAPYVAPIDQSANHTQHTNKMRSRLSHQTRNKETRTAEEEAPPPLDLPQISFPDMASAPKFDLIIKPTVPVVSKPSTTDPIQSSKSSNTNLSTTNSKQMPNFLANPQPAAPIVNFAANGNVSAISKPSKRTFTFSEPTPLSNFQENCIPKPKINRKYTFSAPAPLDDLRITNKQSQPTINGTPSSKEWECDTCMVRNKPEINKCVACETAKPVASAAPVQAPLPPSTAAIDTQSFVGFGDRFKKSTTAWECDACMLSNKAEASKCIACETPRKTVAPKVNNFSPLITNAKSNEWECSVCLVRNKVEVSKCVACESAKPGATMALPATSNIAVATPSIITDGFGDRFKKSATAWECDACMLSNKAEASKCIACETPRKSSTPIANSSYPSINNNLPAGSGFDISFTRKANMWECQTCLVMNKSSDEECIACQTPNSQARNSNSESALISSISSSSASFSGSLSRPSSRSSSGSTSTCGSVCSGSIVSISSTTESAKALSAKKVPPKPDAGFQQLVAAQKTSTWECEACLAKNDMSRKTCICCEQMMPEAFNPAATTANSAASSVPKFRFGFSHVKEVVKPSVETTTTPAPTSAQFSFGFGQSNQGKDVADSKKTEAPKTFMFGVSKVEEPKTVSFGTGIKETTATSSTEATAPTPAAAAPAPVQFVFKAPTTATTASSLTTTISTTSNAPALGGFSFGAPSSSSTVSSSTTSTSANPAAVKPMFSWSGAGSAVSSTSSSQQPVAKAPTLGFGVSSSTVTTTTTSTKVFAFTPASGLDPAAATSAPAAGAGFSFGSQSKPATTQNTGTFFFGQPTAVAPATPTNPSVSSIFGAPATSTTASTSVSATTSTSTANAIASSFAPTSTPQLFGNWGEKKTDLTTFGASSGSGTTTTPSFGWSSNGDAAKSNSAAVGSAAVPSSSASTMATPIFGSSSMFGPSSSSNNTTSTSTTSLPFGSAATTAATTPAGGNAALTGLFGNVGNSLAGVGAPVATTPAATAAAPLTNIFGNPTPVAAAAPVFGSGSTIPSAGFGAPAAAAPLAAPALPGAFNFGGATAATPAASSAPFVFGSSTNEPLAKPSFNFTGSAASSTAPAPAFNFTANTAATNNPSGGDSTPNANALFQFSATSTAPANIFAFNPPAAGNSAQSSQTARRKIRAPVRRLPPR", "length": 1883 }, "evidence": [ { "id": "A0A8V0YGY2", "url": "https://omabrowser.org/oma/group/A0A8V0YGY2/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 7, "go_terms": [ { "name": "negative regulation of RNA export from nucleus", "id": "GO:0046832", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046832", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGY2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGY2" } ], "pmid": "" }, { "name": "amyloid fibril formation", "id": "GO:1990000", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990000", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGY2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGY2" } ], "pmid": "" }, { "name": "nuclear pore complex assembly", "id": "GO:0051292", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051292", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGY2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGY2" } ], "pmid": "" }, { "name": "mRNA transport", "id": "GO:0051028", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051028", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGY2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGY2" } ], "pmid": "" }, { "name": "RNA export from nucleus", "id": "GO:0006405", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006405", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGY2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGY2" } ], "pmid": "" }, { "name": "protein import into nucleus", "id": "GO:0006606", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006606", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGY2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGY2" } ], "pmid": "" }, { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGY2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGY2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "nuclear pore nuclear basket", "id": "GO:0044615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044615", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGY2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGY2" } ], "pmid": "" }, { "name": "nuclear pore", "id": "GO:0005643", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005643", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGY2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGY2" } ], "pmid": "" }, { "name": "nuclear membrane", "id": "GO:0031965", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031965", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGY2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGY2" } ], "pmid": "" }, { "name": "nuclear periphery", "id": "GO:0034399", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034399", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGY2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGY2" } ], "pmid": "" }, { "name": "nuclear inclusion body", "id": "GO:0042405", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042405", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGY2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGY2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 7, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGY2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGY2" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGY2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGY2" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGY2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGY2" } ], "pmid": "" }, { "name": "protein-membrane adaptor activity", "id": "GO:0043495", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043495", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGY2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGY2" } ], "pmid": "" }, { "name": "structural constituent of nuclear pore", "id": "GO:0017056", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017056", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGY2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGY2" } ], "pmid": "" }, { "name": "nuclear localization sequence binding", "id": "GO:0008139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008139", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGY2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGY2" } ], "pmid": "" }, { "name": "molecular condensate scaffold activity", "id": "GO:0140693", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140693", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGY2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGY2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1025, "end_pos": 1027, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1133, "end_pos": 1135, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1187, "end_pos": 1189, "annotation": "n_glycosylation_sequon" }, { "start_pos": 120, "end_pos": 122, "annotation": "n_glycosylation_sequon" }, { "start_pos": 136, "end_pos": 138, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1388, "end_pos": 1390, "annotation": "n_glycosylation_sequon" }, { "start_pos": 179, "end_pos": 181, "annotation": "n_glycosylation_sequon" }, { "start_pos": 200, "end_pos": 202, "annotation": "n_glycosylation_sequon" }, { "start_pos": 231, "end_pos": 233, "annotation": "n_glycosylation_sequon" }, { "start_pos": 244, "end_pos": 246, "annotation": "n_glycosylation_sequon" }, { "start_pos": 423, "end_pos": 425, "annotation": "n_glycosylation_sequon" }, { "start_pos": 486, "end_pos": 488, "annotation": "n_glycosylation_sequon" }, { "start_pos": 62, "end_pos": 64, "annotation": "n_glycosylation_sequon" }, { "start_pos": 72, "end_pos": 74, "annotation": "n_glycosylation_sequon" }, { "start_pos": 973, "end_pos": 975, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YGY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGY2" }, { "id": "PS50199", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50199" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RanBP2-type", "eco_id": "ECO_0000259", "start_pos": 717, "end_pos": 746, "start_aa": "Ala", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 1206 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1025, "end_pos": 1027 }, { "start_pos": 1133, "end_pos": 1135 }, { "start_pos": 1187, "end_pos": 1189 }, { "start_pos": 120, "end_pos": 122 }, { "start_pos": 136, "end_pos": 138 }, { "start_pos": 1388, "end_pos": 1390 }, { "start_pos": 179, "end_pos": 181 }, { "start_pos": 200, "end_pos": 202 }, { "start_pos": 231, "end_pos": 233 }, { "start_pos": 244, "end_pos": 246 }, { "start_pos": 423, "end_pos": 425 }, { "start_pos": 486, "end_pos": 488 }, { "start_pos": 62, "end_pos": 64 }, { "start_pos": 72, "end_pos": 74 }, { "start_pos": 973, "end_pos": 975 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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"o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YGZ0-1", "uniprot_ac": "A0A8V0YGZ0", "uniprot_id": "A0A8V0YGZ0_CHICK", "mass": { "chemical_mass": 94531.0, "monoisotopic_mass": 94531.0 }, "refseq": { "ac": "XP_040560740", "name": "zinc finger protein 281", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040560740" }, "gene_names": [ { "name": "LOC107053919", "type": "recommended", "evidence": [ { "id": "A0A8V0YGZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGZ0" } ] }, { "name": "LOC107053919", "type": "synonym", "evidence": [ { "id": "XP_040560740", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040560740" } ] } ], "protein_names": [ { "name": "Zinc finger protein 281", "type": "recommended", "evidence": [ { "id": "A0A8V0YGZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGZ0/entry#names_and_taxonomy" } ] }, { "name": "zinc finger protein 281", "type": "synonym", "evidence": [ { "id": "XP_040560740", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040560740" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052539.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040560740", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040560740" } ] }, { "annotation": "Transcription repressor that plays a role in regulation of embryonic stem cells (ESCs) differentiation. Required for ESCs differentiation and acts by mediating autorepression of NANOG in ESCs: binds to the NANOG promoter and promotes association of NANOG protein to its own promoter and recruits the NuRD complex, which deacetylates histones. Not required for establishement and maintenance of ESCs. Represses the transcription of a number of genes including GAST, ODC1 and VIM. Binds to the G-rich box in the enhancer region of these genes.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGZ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGZ0#function" }, { "database": "UniProtKB", "id": "ARBA00059547", "url": "https://www.uniprot.org/uniprotkb/ARBA00059547#function" }, { "database": "UniProtKB", "id": "A0A8V0YLR4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLR4#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGZ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGZ0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LOC107053919", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGZ0", "locus": {} } ], "crossref": [ { "id": "107053919", "url": "https://www.ncbi.nlm.nih.gov/gene/107053919", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "FPPGMVM", "url": "https://omabrowser.org/oma/group/FPPGMVM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YGZ0", "url": "https://www.orthodb.org/?gene=A0A8V0YGZ0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YLR4", "url": "https://www.orthodb.org/?gene=A0A8V0YLR4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23235", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23235", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23235:SF155", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23235:SF155", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_040560740", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040560740", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YGZ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGZ0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YGZ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGZ0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLR4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLR4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLR4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLR4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKLGGGFLGGGKRAAAMEPGFPPGMVMFNHRLPPVTSFTRAAAPPPAAQHPPQCALPPPSAAASSAAEPPAPPAPQDVTFKKEPAGAFPSAPSSAQRGPWGFLQSLVSIKQEKPSEQEEEEPPPQHHHYGGLFGAPGEERPPGLGGGGGEGGGQSVIQDLSLLQHLHQHPPRDLLLGGRAEGGPGGSGEPKHDAQVKKAKRPKPETQGIKAKRKPGASSKPPLVGDAEGAVASPSQKPHVCEHCSAAFRSSYHLRRHVLIHTGERPFQCSQCSMGFIQKYLLQRHEKIHSREKPFGCDQCSMKFIQKYHMERHKRTHSGEKPYKCDTCQQYFSRTDRLLKHRRTCGEAIGKAGAGMEPGSSHNMGSLAALSQGNTNSSRRKSKTKSISTENKGNKCSSKVAESQVTSNVAMPNYAVDIPIVSSSGGLVGTGVEELQKKVPKLVFKKGSRKQADKNYLNFVSPLPDILGQKPLSGKQSGSLGSLVANTSVENIGLLQSPSGKSGQINSNYDDAMQFSKKRRYLQTASGNSAFSINVGHMTSQQSVIQSAGVSVMDNETPLSLIDSASLNSEIKTCHDKSGIPDEVLQSLLDQYSHKSEGQKEDPFSITEQRVDLHSSGEHSEMVQEENLSPNSQTVSNDKASMLQEYSKYLQQAFERTTNSTGFAFGPSFQFVSLSSTLHNHTLFQDKQIYTTSPLECGFSQSVTSVLPTALPKPPFGMLLGSQPGFYLSALEATHQQLTPSQELDDLIDPQKTLETSSNYQSTSQKLTGQKEQKNLESSTSFQIPSQELASQIDPQKDIEPRATYQIENFAQAFGSQFKSGSRVPMTFITNSNGEVDHRVRTSVSDFSGYSNMMSDVSEPCSTRVKTPTSQSYR", "length": 874, "header": "tr|A0A8V0YGZ0-1|A0A8V0YGZ0_CHICK Isoform 1 of Zinc finger protein 281 OS=Gallus gallus OX=9031 GN=LOC107053919 PE=3 SV=1 CANONICAL=A0A8V0YGZ0-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YGZ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGZ0/entry#A0A8V0YGZ0-1", "sequence": { "sequence": "MKLGGGFLGGGKRAAAMEPGFPPGMVMFNHRLPPVTSFTRAAAPPPAAQHPPQCALPPPSAAASSAAEPPAPPAPQDVTFKKEPAGAFPSAPSSAQRGPWGFLQSLVSIKQEKPSEQEEEEPPPQHHHYGGLFGAPGEERPPGLGGGGGEGGGQSVIQDLSLLQHLHQHPPRDLLLGGRAEGGPGGSGEPKHDAQVKKAKRPKPETQGIKAKRKPGASSKPPLVGDAEGAVASPSQKPHVCEHCSAAFRSSYHLRRHVLIHTGERPFQCSQCSMGFIQKYLLQRHEKIHSREKPFGCDQCSMKFIQKYHMERHKRTHSGEKPYKCDTCQQYFSRTDRLLKHRRTCGEAIGKAGAGMEPGSSHNMGSLAALSQGNTNSSRRKSKTKSISTENKGNKCSSKVAESQVTSNVAMPNYAVDIPIVSSSGGLVGTGVEELQKKVPKLVFKKGSRKQADKNYLNFVSPLPDILGQKPLSGKQSGSLGSLVANTSVENIGLLQSPSGKSGQINSNYDDAMQFSKKRRYLQTASGNSAFSINVGHMTSQQSVIQSAGVSVMDNETPLSLIDSASLNSEIKTCHDKSGIPDEVLQSLLDQYSHKSEGQKEDPFSITEQRVDLHSSGEHSEMVQEENLSPNSQTVSNDKASMLQEYSKYLQQAFERTTNSTGFAFGPSFQFVSLSSTLHNHTLFQDKQIYTTSPLECGFSQSVTSVLPTALPKPPFGMLLGSQPGFYLSALEATHQQLTPSQELDDLIDPQKTLETSSNYQSTSQKLTGQKEQKNLESSTSFQIPSQELASQIDPQKDIEPRATYQIENFAQAFGSQFKSGSRVPMTFITNSNGEVDHRVRTSVSDFSGYSNMMSDVSEPCSTRVKTPTSQSYR", "length": 874, "header": "tr|A0A8V0YGZ0-1|A0A8V0YGZ0_CHICK Isoform 1 of Zinc finger protein 281 OS=Gallus gallus OX=9031 GN=LOC107053919 PE=3 SV=1 CANONICAL=A0A8V0YGZ0-1" }, "locus": { "chromosome": "8", "start_pos": 1532418, "end_pos": 1532255, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029338.1", "url": "https://www.ensembl.org/id/ENSGALT00010029338.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017036.1", "url": "https://www.ensembl.org/id/ENSGALP00010017036.1" } ] } }, { "isoform_ac": "A0A8V0YLR4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGZ0/entry#A0A8V0YLR4-1", "sequence": { "sequence": "MKLGGGFLGGGKRAAAMEPGFPPGMVMFNHRLPPVTSFTRAAAPPPAAQHPPQCALPPPSAAASSAAEPPAPPAPQDVTFKKEPAGAFPSAPSSAQRGPWGFLQSLVSIKQEKPSEQEEEEPPPQHHHYGGLFGAPGEERPPGLGGGGGEGGGQSVIQDLSLLQHLHQHPPRDLLLGGRAEGGPGGSGEPKHDAQVKKAKRPKPETQGIKAKRKPGASSKPPLVGDAEGAVASPSQKPHVCEHCSAAFRSSYHLRRHVLIHTGERPFQCSQCSMGFIQKYLLQRHEKIHSREKPFGCDQCSMKFIQKYHMERHKRTHSGEKPYKCDTCQQYFSRTDRLLKHRRTCGEAIGKAGAGMEPGSSHNMGSLAALSQGNTNSSRRKSKTKSISTENKGNKCSSKVAESQVTSNVAMPNYAVDIPIVSSSGGLVGTGVEELQKKVPKLVFKKGSRKQADKNYLNFVSPLPDILGQKPLSGKQSGSLGSLVANTSVENIGLLQSPSGKSGQINSNYDDAMQFSKKRRYLQTASGNSAFSINVGHMTSQQSVIQSAGVSVMDNETPLSLIDSASLNSEIKTCHDKSGIPDEVLQSLLDQYSHKSEGQKEDPFSITEQRVDLHSSGEHSEMVQEENLSPNSQTVSNDKASMLQEYSKYLQQAFERTTNSTGFAFGPSFQFVSLSSTLHNHTLFQDKQIYTTSPLECGFSQSVTSVLPTALPKPPFGMLLGSQPGFYLSALEATHQQLTPSQELDDLIDPQKTLETSSNYQSTSQKLTGQKEQKNLESSTSFQIPSQELASQIDPQKDIEPRATYQIENFAQAFGSQFKSGSRVPMTFITNSNGEVDHRKSGSIASLSSGEALKNRRLQFGSRRTREK", "length": 868, "header": "tr|A0A8V0YLR4-1|A0A8V0YLR4_CHICK Computationally mapped isoform of Zinc finger protein 281 OS=Gallus gallus OX=9031 GN=LOC107053919 PE=3 SV=1 CANONICAL=A0A8V0YGZ0-1" }, "locus": { "chromosome": "8", "start_pos": 1531636, "end_pos": 1526210, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029335.1", "url": "https://www.ensembl.org/id/ENSGALT00010029335.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017034.1", "url": "https://www.ensembl.org/id/ENSGALP00010017034.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0AAA9SNV6-1", "protein_name": "Zinc finger protein 281", "gene_name": "ZNF281", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MKVGSAFLSGGGGGAGSGGRAEMEPSFPPGMVMFNHRLPPVASFARPAGAAAPPPQCVLAAAPAAAPAAEPPPAPAPDVTFKKEPAAPGAAFPAQRTPWGFLQSLVSIKQEKPADPDEPPGAPHPHYGGLFAGADERAPGLGGGDGGGAGVIQDLSALHPPPPAPHQHPHPRDVLLGRTDDPRGPEEPKPDASVKKAKRPKPESQGIKAKRKPGASSKPPPAGDGEGSVLSPSQKPHVCDHCSAAFRSSYHLRRHVLIHTGERPFQCGQCSMGFIQKYLLQRHEKIHSREKPFGCDQCSMKFIQKYHMERHKRTHSGEKPYRCDTCQQYFSRTDRLLKHRRTCGEALGKGAPGAEPGSSGSHSGVGNLAVLSQGNTSSSRRKAKSKSLAVESKEPKAGKANESHLSTSMNTQSYSVEMPAVPSSGGIVGPDIDELQKRVPKLIFKKGSRKSTDKSYLNFVSPLPDLVGQKSLSGKPSGSLGIVSNSSVETISLLQSTGGKQGQISSNYDDAMQFSKKRRYLPTASSNSAFSVSVGHMVSPQSVIQSAGVGVLDSEAPLSLIDSSALNAEIKSCHDKSGIPDEVLQSILDQYSNKSESQKEDPFSIAEPRVDLHASGEHSELVQEENLSPGTQTPSNDKASMLQEYSKYLQQAFEKSTNAGFTLGHGFQFVSLSSPLHNHTLFPEKQIYTTSPLECGFGQSVTSVLPSSLPKPPFGMLFGSQPGLYLSALDATHQQLTPSQELDDLIDSQKNLETSSAFQSSSQKLTSQKEQQKNLESSTSFQIPSQELASQIDPQKDVEPRTTYQIENFAQAFGSQFKSGSRVPMTFITNSNGEVDHRARTSVSDFSGYTNMMSDVSEPCSTRVKTPTSQSYRSALPAKVSLICHCKILRKRV", "length": 893 }, "evidence": [ { "id": "A0A8V0YGZ0", "url": "https://omabrowser.org/oma/group/A0A8V0YGZ0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1QM98-1", "protein_name": "Zinc finger protein 281", "gene_name": "znf281b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSIIQDKLGNEFLRNGGMDPNYTPSMIMFSHLPPVTSFTRLTSQTSMADLPQEMILKKERDSPEHGGGFLHSMGIKQEKLNELDYHLPMYTTGIGTAGGKNTDMLDMSLGNHQNMLLHDLSLSNQFSGRLGKDPKETGPRKGRRANGEGLEGKARRKQGDSGKTLMLDGDAGPLSPSSKPHICEHCSAAFRSSYHLRRHVLIHTGERPFRCSQCNMSFIQKYLLQRHEKIHSGEKPFSCDQCNMRFIQKYHMERHKRTHSGEKPYKCDTCLQYFSRTDRLLKHKRTCGEAIKKGLDPGMLDLGDEDMGQGSYLLAQGNTSGPPRKKGKSKIGNDGGERRRKKGAAAGVRMARDDYNLDIPSGSGTASGALAEASMDNQHGGRTSKPVFKKGSRKGMDKCSVSVEEASHEQKLLTQKSSSMDMSGAGSMDGLGLLQNSGGTKQGGNSSNYDDAMQFLKKRRYLHAANSNATADFSSVHLPQPTVIQGGIGEPTLALLDTSPLVSVDKHDKSGIPDEVLQSLLDHYSHKSDGSHHDVTFDLQDSHHVELQPATGTSDLGPDNGSPGSGDKSGMMNEYSKFLLQTLERTSHSSNFILGPSGPFPSLMSSSSSPASSLYTTSPLECGFVQPVSSPLAPSSSTSLSKSHFGMLVGSPSPSHASPSSQQAFHLSSLEPTPHQQLTPSQELTDQLEKQHSPPYSLTSQELTNGGQKDQQTKNGSSSANGSNNGNVPSGGSSNGSVYSDLTALEPSKEVTYQIENFAQAFGSQFKSGRRTPLGYGGDPRVGVVEVDHRIQRTPVSEFSGYTSLLADVNEPASSGSKTPTSQSYR", "length": 826 }, "evidence": [ { "id": "A0A8V0YGZ0", "url": "https://omabrowser.org/oma/group/A0A8V0YGZ0/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1S5D4-1", "protein_name": "Zinc finger protein 281", "gene_name": "ZNF281", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MKVGSAFLSGGGGGAGSGGRAEMEPSFPPGMVMFNHRLPPVASFARPAGAAAPPPQCVLAAAPAAAPAAEPPPAPAPDVTFKKEPAAPGAAFPAQRTSWGFLQSLVSIKQEKPAEPEEPPGAPHPHYGGLFAGADERAPALGGGDGGGPGVIQDLSVLHPPPAPHPRDVLLGGGGRTDDPRGPEEPKQDAGVKKAKRPKPESQGIKAKRKPSASSKPSLVGDGEGAVLSPSQKPHICDHCSAAFRSSYHLRRHVLIHTGERPFQCSQCSMGFIQKYLLQRHEKIHSREKPFGCDQCSMKFIQKYHMERHKRTHSGEKPYKCDTCQQYFSRTDRLLKHRRTCGEAIAKGAPNSEPGSSNHSSLGSLAVLSQGNTSSSRRKAKSKSLAIENKEPKTGKANESPISNSISMQNYSVEMPTVSSSGGVIGSGIDELQKRVPKLIFKKGSRKSTDKNYLNFVSPLPDLVGQKSLSGKPSGSLGIVSSSSVETIGLLQSTSGKQGQIGSNYDDAMQFSKKRRYLPTASSNSAFSVNVGHMVSQQSVIQSAGVGVLDSEAPLSLIDSSALNAEIKACHDKSGIPDEVLQSILDQYSSKSESQKEDPFSITEPRVDLHTSGDHSELVQEDNLSPGTQTPSNDKASMLQEYSKYLQQAFEKSTNAGFTLGHGFQFVSLSSPLHNHSLFPEKQIYTTSPLECGFGQSVTSVLPSSLPKPPFGMLFGSQPGLYLSALDATHQQLTPSQELDDLIDSQKNLETSSAFQASSQKLTSQKEQQKNLESSAGFQIPSQELASQIDPQKDVEPRTTYQIENFAQAFGSQFKSGSRVPMTFITNSNGEVDHRARTSVSDFSGYTNMMSDVSEPCSTRVKTPTSQSYR", "length": 870 }, "evidence": [ { "id": "A0A8V0YGZ0", "url": "https://omabrowser.org/oma/group/A0A8V0YGZ0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q99LI5-1", "protein_name": "Zinc finger protein 281", "gene_name": "Znf281", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKIGSGFLSGGGGPSSSGGSGSGGSSGSASGGSGGGRRAEMEPTFPQSMVMFNHRLPPVTSFTRPAGTAAPPPQCVLSSSTSAAPAAEPPPPPAPDMTFKKEPAASAAAFPSQRTSWGFLQSLVSIKQEKPADPEEQPSHHHHHHHHYGGLFAGAEERSPGLGGGEGGSHGVIQDLSLLHQHAQQQPAQHHRDVLLSSGSRTDEHGNQEPKQDANVKKAKRPKPESQGIKAKRKPSASSKPLVGEGEGAVLSPSQKPHICDHCSAAFRSSYHLRRHVLIHTGERPFQCSQCSMGFIQKYLLQRHEKIHSREKPFGCDQCSMKFIQKYHMERHKRTHSGEKPYKCDTCQQYFSRTDRLLKHRRTCGEAIAKGAASAEPGSSNHNSMGNLAVLSQGNTSSSRRKSKSKSIAIENKEHKTGKTNESQMSNNINMQSYSVEMPTVSTSGSIIGTGIDELQKRVPKLIFKKGSRKNADKSYLNFVSPLPDVVGQKSLSGKPGGSLGIVSNNSVETISLLQSTSGKQGPISSNYDDAMQFSKKRRYLPTASSNSAFSINVGHMVSQQSVIQSAGVSVLDNEAPLSLIDSSALNAEIKSCHDKSGIPDEVLQSILDQYSGKSETQKEDPFNLTEPRVDLHTSGEHSELVQEENLSPGTQTPSNDKTSMLQEYSKYLQQAFEKSTNAGFTLGHGFQFVSLSSPLHNHTLFPEKQIYTTSPLECGFGQSVTSVLPSSLPKPPFGMLFGSQPGLYLSALDATHQQLTPSQELDDLIDSQKNLETSSAFQSSSQKLTSQKEQQKNLESSTSFQIPSQELASQIDPQKDIEPRTTYQIENFAQAFGSQFKSGSRVPMTFITNSNGEVDHRVRTSVSDFSGYTNMMSDVSEPCSTRVKTPTSQSYR", "length": 893 }, "evidence": [ { "id": "A0A8V0YGZ0", "url": "https://omabrowser.org/oma/group/A0A8V0YGZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9Y2X9-1", "protein_name": "Zinc finger protein 281", "gene_name": "ZNF281", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKIGSGFLSGGGGTGSSGGSGSGGGGSGGGGGGGSSGRRAEMEPTFPQGMVMFNHRLPPVTSFTRPAGSAAPPPQCVLSSSTSAAPAAEPPPPPAPDMTFKKEPAASAAAFPSQRTSWGFLQSLVSIKQEKPADPEEQQSHHHHHHHHYGGLFAGAEERSPGLGGGEGGSHGVIQDLSILHQHVQQQPAQHHRDVLLSSSSRTDDHHGTEEPKQDTNVKKAKRPKPESQGIKAKRKPSASSKPSLVGDGEGAILSPSQKPHICDHCSAAFRSSYHLRRHVLIHTGERPFQCSQCSMGFIQKYLLQRHEKIHSREKPFGCDQCSMKFIQKYHMERHKRTHSGEKPYKCDTCQQYFSRTDRLLKHRRTCGEVIVKGATSAEPGSSNHTNMGNLAVLSQGNTSSSRRKTKSKSIAIENKEQKTGKTNESQISNNINMQSYSVEMPTVSSSGGIIGTGIDELQKRVPKLIFKKGSRKNTDKNYLNFVSPLPDIVGQKSLSGKPSGSLGIVSNNSVETIGLLQSTSGKQGQISSNYDDAMQFSKKRRYLPTASSNSAFSINVGHMVSQQSVIQSAGVSVLDNEAPLSLIDSSALNAEIKSCHDKSGIPDEVLQSILDQYSNKSESQKEDPFNIAEPRVDLHTSGEHSELVQEENLSPGTQTPSNDKASMLQEYSKYLQQAFEKSTNASFTLGHGFQFVSLSSPLHNHTLFPEKQIYTTSPLECGFGQSVTSVLPSSLPKPPFGMLFGSQPGLYLSALDATHQQLTPSQELDDLIDSQKNLETSSAFQSSSQKLTSQKEQKNLESSTGFQIPSQELASQIDPQKDIEPRTTYQIENFAQAFGSQFKSGSRVPMTFITNSNGEVDHRVRTSVSDFSGYTNMMSDVSEPCSTRVKTPTSQSYR", "length": 895 }, "evidence": [ { "id": "A0A8V0YGZ0", "url": "https://omabrowser.org/oma/group/A0A8V0YGZ0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGZ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGZ0" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGZ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGZ0" } ], "pmid": "" }, { "name": "DNA-binding transcription repressor activity, RNA polymerase II-specific", "id": "GO:0001227", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001227", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGZ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGZ0" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGZ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGZ0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGZ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGZ0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGZ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGZ0" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", 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{ "start_pos": 555, "end_pos": 557 }, { "start_pos": 627, "end_pos": 629 }, { "start_pos": 659, "end_pos": 661 }, { "start_pos": 680, "end_pos": 682 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", 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{ "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YGZ4-1", "uniprot_ac": "A0A8V0YGZ4", "uniprot_id": "A0A8V0YGZ4_CHICK", "mass": { "chemical_mass": 31356.0, "monoisotopic_mass": 31356.0 }, "refseq": { "ac": "XP_004937622", "name": "leucine-rich repeat-containing protein 10", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004937622" }, "gene_names": [ { "name": "LRRC10", "type": "recommended", "evidence": [ { "id": "A0A8V0YGZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGZ4" } ] }, { "name": "LRRC10", "type": "synonym", "evidence": [ { "id": "XP_004937622", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004937622" } ] } ], "protein_names": [ { "name": "Leucine rich repeat containing 10", "type": "synonym", "evidence": [ { "id": "A0A8V0YGZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGZ4/entry#names_and_taxonomy" } ] }, { "name": "leucine-rich repeat-containing protein 10", "type": "synonym", "evidence": [ { "id": "XP_004937622", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004937622" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_004937622.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004937622", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004937622" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGZ4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGZ4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LRRC10", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGZ4", "locus": { "chromosome": "1", "start_pos": 35641215, "end_pos": 35642961, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010014235", "url": "https://www.ensembl.org/id/ENSGALG00010014235" } ] } } ], "crossref": [ { "id": "A0A8V0YGZ4", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YGZ4", "database": "AlphaFoldDB", "categories": [] }, { "id": "427865", "url": "https://www.ncbi.nlm.nih.gov/gene/427865", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001611", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001611", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003591", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003591", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050216", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050216", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:427865", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427865", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "LWIESNC", "url": "https://omabrowser.org/oma/group/LWIESNC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YGZ4", "url": "https://www.orthodb.org/?gene=A0A8V0YGZ4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48051", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48051", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR48051:SF37", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48051:SF37", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13855", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13855", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_004937622", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004937622", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YGZ4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGZ4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YGZ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGZ4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGNSLKAVVAFVPSDECQKYLLEDLEEMPVDKMVDLSGRQLRRLPLHICSFRELVKLYLSNNNLTQLPPELEQLQNLQILALDFNNFRALPLAVCTLKQLCILYLGNNKLCSLPLELRLLQNLRTLWIESNCLQQLPEVVCELSLLKTLHAGSNALRTLPTRLRGLCELRSIWLSGNLLAEFPSVLLHMPSLEVIDVDRNAIRYFPSLAHLASLKLVIYDHNPCRNAPKVAKGVRRVGRWSEESPEPRKRSGAVIEISLSERPLPPPASKAEPEAEAC", "length": 278, "header": "tr|A0A8V0YGZ4-1|A0A8V0YGZ4_CHICK Isoform 1 of Leucine rich repeat containing 10 OS=Gallus gallus OX=9031 GN=LRRC10 PE=4 SV=1 CANONICAL=A0A8V0YGZ4-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YGZ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGZ4/entry#A0A8V0YGZ4-1", "sequence": { "sequence": "MGNSLKAVVAFVPSDECQKYLLEDLEEMPVDKMVDLSGRQLRRLPLHICSFRELVKLYLSNNNLTQLPPELEQLQNLQILALDFNNFRALPLAVCTLKQLCILYLGNNKLCSLPLELRLLQNLRTLWIESNCLQQLPEVVCELSLLKTLHAGSNALRTLPTRLRGLCELRSIWLSGNLLAEFPSVLLHMPSLEVIDVDRNAIRYFPSLAHLASLKLVIYDHNPCRNAPKVAKGVRRVGRWSEESPEPRKRSGAVIEISLSERPLPPPASKAEPEAEAC", "length": 278, "header": "tr|A0A8V0YGZ4-1|A0A8V0YGZ4_CHICK Isoform 1 of Leucine rich repeat containing 10 OS=Gallus gallus OX=9031 GN=LRRC10 PE=4 SV=1 CANONICAL=A0A8V0YGZ4-1" }, "locus": { "chromosome": "1", "start_pos": 35642899, "end_pos": 35642066, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034280.1", "url": "https://www.ensembl.org/id/ENSGALT00010034280.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020140.1", "url": "https://www.ensembl.org/id/ENSGALP00010020140.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:427865", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427865", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8D0PUJ4-1", "protein_name": "Leucine rich repeat containing 10", "gene_name": "LRRC10", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "GNTIRALVAFIPADRCQKYVVRDLQEMPLDKMVDLSGNQLRRFPVHVCSFQELVKLYLSDNHLNSLPPELGQLQNLQILALDFNNFKVLPQVVCTLKQLCILYLGNNKLCDLPSELSLLQNLRTLWVEANYLTQLPDVVCELSLLKTLHAGSNALRLLPGQLQRLQELRTIWLSGNLLTDFPPVLLHMPFLEVIDVDQNSIRYFPSLAHLSSLKLVIYDHNPCRNAPKVAKGVRRVGRWAEETPEPDPRKARRYALVREESQEAQVPALLPPFPPTNS", "length": 278 }, "evidence": [ { "id": "A0A8V0YGZ4", "url": "https://omabrowser.org/oma/group/A0A8V0YGZ4/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "D4AAU8-1", "protein_name": "Leucine-rich repeat-containing protein 10", "gene_name": "Lrrc10", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGNIIRALVAFIPTDRCQSYVVGDLREMPLDRMVDLSGSQLRRFPLHVCSFTELVKLYLSDNHLHSLPPDLAQLQNLQILALDFNNFKALPQAVCTLKQLCILYLGNNKLCDLPDELSLLQNLRTLWLESNCLTRLPDVVCELSLLKTLHAGSNALRLLPGQLRRLRELRTIWLSGNQLADFPSVLLHMPFLEVIDVDRNSIRYFPSLAHLTNLKLVIYDHNPCRNAPKVGKGVRRVGRWAEETPEPDRRKTRRSALAKEENQEPPPLLPPSS", "length": 273 }, "evidence": [ { "id": "A0A8V0YGZ4", "url": "https://omabrowser.org/oma/group/A0A8V0YGZ4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q24K06-1", "protein_name": "Leucine-rich repeat-containing protein 10", "gene_name": "LRRC10", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGNTIRAFVAFIPADRCQNYVARDLREMPLDRMVDLSGSQLRRFPVHVCSFQELVKLYLSDNRLNSLPPELGQLQNLQILALDFNNFKALPQVVCTLKQLCILYLGNNKLCDLPRELSLLQNLRTLWVEANYLTKLPEVVCELSLLKTLHAGSNALRLLPGQLQRLRELRTIWLSGNLLTDFPPVLLHMPFLEIIDVDRNSIRYFPSLAHLSSLKLVIYDHNPCRNAPKVAKGVRRVGRWAEETPEPDPRKARRYALAREESQEAQLPALPPLPPTNS", "length": 278 }, "evidence": [ { "id": "A0A8V0YGZ4", "url": "https://omabrowser.org/oma/group/A0A8V0YGZ4/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q5BKY1-1", "protein_name": "Leucine-rich repeat-containing protein 10", "gene_name": "LRRC10", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGNTIRALVAFIPADRCQNYVVRDLREMPLDKMVDLSGSQLRRFPLHVCSFRELVKLYLSDNHLNSLPPELGQLQNLQILALDFNNFKALPQVVCTLKQLCILYLGNNKLCDLPSELSLLQNLRTLWIEANCLTQLPDVVCELSLLKTLHAGSNALRLLPGQLRRLQELRTIWLSGNRLTDFPTVLLHMPFLEVIDVDWNSIRYFPSLAHLSSLKLVIYDHNPCRNAPKVAKGVRRVGRWAEETPEPDPRKARRYALVREESQELQAPVPLLPPTNS", "length": 277 }, "evidence": [ { "id": "A0A8V0YGZ4", "url": "https://omabrowser.org/oma/group/A0A8V0YGZ4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8K3W2-1", "protein_name": "Leucine-rich repeat-containing protein 10", "gene_name": "Lrrc10", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGNTIRAFVAFIPTDRCQSYVVGDLREMPLDRMVDLSGSQLRRFPLHVCSFTELVKLYLSDNHLHSLPPDLAQLQNLQILALDFNNFKALPRVVCTLKQLCILYLGNNKLCDLPDELSLLQNLRTLWLESNCLTRLPDVVCELSLLKTLHAGSNALRLLPGQLRRLRELRTIWLSGNQLADFPSVLLRMPFLEVIDVDRNSIRYFPSLAHLTNLKLVIYDHNPCRNAPKVGKGVRRVGRWAEETPEPDPRKARRYALAKEENQEPPPPLLPSSS", "length": 274 }, "evidence": [ { "id": "A0A8V0YGZ4", "url": "https://omabrowser.org/oma/group/A0A8V0YGZ4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "actin binding", "id": "GO:0003779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003779", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGZ4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGZ4" } ], "pmid": "" }, { "name": "alpha-actinin binding", "id": "GO:0051393", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051393", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGZ4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGZ4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGZ4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGZ4" } ], "pmid": "" }, { "name": 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"UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH00/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YH00", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH00" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH00", "locus": {} } ], "crossref": [ { "id": "A0A8V0YH00", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YH00", "database": "AlphaFoldDB", "categories": [] }, { "id": "A0A8V0YH00", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH00", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YH00-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH00-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVELEGTFQAPQVPIPCNEQGHPQLHRSLGAPSPSPSSACLEQQVPQSPQLADPAPQVLPSTFSRACPVRPKLCSWHRASAAHCIYRNCLVPTLLISVQLNPTNCHHETEHVKALAIEKCCTAMDVIPKGSQTVLPLLAFS", "length": 141, "header": "tr|A0A8V0YH00-1|A0A8V0YH00_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0YH00-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YH00-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH00/entry#A0A8V0YH00-1", "sequence": { "sequence": "MVELEGTFQAPQVPIPCNEQGHPQLHRSLGAPSPSPSSACLEQQVPQSPQLADPAPQVLPSTFSRACPVRPKLCSWHRASAAHCIYRNCLVPTLLISVQLNPTNCHHETEHVKALAIEKCCTAMDVIPKGSQTVLPLLAFS", "length": 141, "header": "tr|A0A8V0YH00-1|A0A8V0YH00_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0YH00-1" }, "locus": { "chromosome": "13", "start_pos": 15437474, "end_pos": 15435187, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030704.1", "url": "https://www.ensembl.org/id/ENSGALT00010030704.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017805.1", "url": "https://www.ensembl.org/id/ENSGALP00010017805.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": 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"count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YH04-1", "uniprot_ac": "A0A8V0YH04", "uniprot_id": "A0A8V0YH04_CHICK", "mass": { "chemical_mass": 57896.0, "monoisotopic_mass": 57896.0 }, "refseq": { "ac": "XP_046795563", "name": "sestrin-1 isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046795563" }, "gene_names": [ { "name": "SESN1", "type": "recommended", "evidence": [ { "id": "A0A8V0YH04", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH04" } ] }, { "name": "SESN1", "type": "synonym", "evidence": [ { "id": "XP_046795563", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046795563" } ] } ], "protein_names": [ { "name": "Sestrin 1", "type": "synonym", "evidence": [ { "id": "A0A8V0YH04", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH04/entry#names_and_taxonomy" } ] }, { "name": "sestrin-1 isoform X3", "type": "synonym", "evidence": [ { "id": "XP_046795563", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046795563" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052534.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_046795563", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046795563" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YH04", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH04" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SESN1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH04", "locus": { "chromosome": "3", "start_pos": 66837803, "end_pos": 66824452, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010014244", "url": "https://www.ensembl.org/id/ENSGALG00010014244" } ] } } ], "crossref": [ { "id": "A0A8V0YH04", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YH04", "database": "AlphaFoldDB", "categories": [] }, { "id": "421766", "url": "https://www.ncbi.nlm.nih.gov/gene/421766", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006730", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006730", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029032", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029032", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YH04", "url": "https://www.orthodb.org/?gene=A0A8V0YH04", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YND6", "url": "https://www.orthodb.org/?gene=A0A8V0YND6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12474", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12474", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12474:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12474:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04636", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04636", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-5628897", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5628897", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9639288", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9639288", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9755511", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9755511", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_046795563", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046795563", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "67124", "url": "https://www.rhea-db.org/rhea/67124", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YH04", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH04", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YH04-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH04-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YND6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YND6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YND6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YND6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLLLKGFRTKADDVLLPTEPRRVVLQELGIRIPRPLGHGPSRFIPEKETVQVGSEDAMMHALFADSFATLGRLDNVTLVMVFHPQYLESFLKTQHYLLQMDGPLPLHYRHYIGIMAAARHQCSYLVNLHVNDFLHVGGDPKWLNGLENAPQKLQNLGELNKMLAHRPWLITKEHIEQLLKTEENSWSLAELIHAVVLLTHYHSLASFTFGCGISPEIDCEGGHTFRPPSVSNYCLCDITNGYHGVDDIHASPAASIPTTESVCEVEALMEKMKQLQECRDEEEASQEEMATRFEREKRESMFVCSSEDEESAPTRDVSRHFEDTSYGYKDFSRHGMHVPTFRAQDYSWEDHGYSLVNRLYPDVGQLLDEKFHIAYNLTYNTMAMHKDVDTSMLRRAIWNYIHCMFGIRYDDYDYGEINQLLDRSFKVYIKTVVCTPEKTTKRMYDSFWRQFEHSEKGQTTLPPLPLLTTPSAPQVHVNLLLVEARMQAELLYALRAITRYMT", "length": 502, "header": "tr|A0A8V0YH04-1|A0A8V0YH04_CHICK Isoform 1 of Sestrin 1 OS=Gallus gallus OX=9031 GN=SESN1 PE=3 SV=1 CANONICAL=A0A8V0YH04-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YH04-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH04/entry#A0A8V0YH04-1", "sequence": { "sequence": "MLLLKGFRTKADDVLLPTEPRRVVLQELGIRIPRPLGHGPSRFIPEKETVQVGSEDAMMHALFADSFATLGRLDNVTLVMVFHPQYLESFLKTQHYLLQMDGPLPLHYRHYIGIMAAARHQCSYLVNLHVNDFLHVGGDPKWLNGLENAPQKLQNLGELNKMLAHRPWLITKEHIEQLLKTEENSWSLAELIHAVVLLTHYHSLASFTFGCGISPEIDCEGGHTFRPPSVSNYCLCDITNGYHGVDDIHASPAASIPTTESVCEVEALMEKMKQLQECRDEEEASQEEMATRFEREKRESMFVCSSEDEESAPTRDVSRHFEDTSYGYKDFSRHGMHVPTFRAQDYSWEDHGYSLVNRLYPDVGQLLDEKFHIAYNLTYNTMAMHKDVDTSMLRRAIWNYIHCMFGIRYDDYDYGEINQLLDRSFKVYIKTVVCTPEKTTKRMYDSFWRQFEHSEKGQTTLPPLPLLTTPSAPQVHVNLLLVEARMQAELLYALRAITRYMT", "length": 502, "header": "tr|A0A8V0YH04-1|A0A8V0YH04_CHICK Isoform 1 of Sestrin 1 OS=Gallus gallus OX=9031 GN=SESN1 PE=3 SV=1 CANONICAL=A0A8V0YH04-1" }, "locus": { "chromosome": "3", "start_pos": 66836755, "end_pos": 66826070, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034299.1", "url": "https://www.ensembl.org/id/ENSGALT00010034299.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020150.1", "url": "https://www.ensembl.org/id/ENSGALP00010020150.1" } ] } }, { "isoform_ac": "A0A8V0YND6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH04/entry#A0A8V0YND6-1", "sequence": { "sequence": "MLCATLLLLNQELGIRIPRPLGHGPSRFIPEKETVQVGSEDAMMHALFADSFATLGRLDNVTLVMVFHPQYLESFLKTQHYLLQMDGPLPLHYRHYIGIMAAARHQCSYLVNLHVNDFLHVGGDPKWLNGLENAPQKLQNLGELNKMLAHRPWLITKEHIEQLLKTEENSWSLAELIHAVVLLTHYHSLASFTFGCGISPEIDCEGGHTFRPPSVSNYCLCDITNGYHGVDDIHASPAASIPTTESVCEVEALMEKMKQLQECRDEEEASQEEMATRFEREKRESMFVCSSEDEESAPTRDVSRHFEDTSYGYKDFSRHGMHVPTFRAQDYSWEDHGYSLVNRLYPDVGQLLDEKFHIAYNLTYNTMAMHKDVDTSMLRRAIWNYIHCMFGIRYDDYDYGEINQLLDRSFKVYIKTVVCTPEKTTKRMYDSFWRQFEHSEKVHVNLLLVEARMQAELLYALRAITRYMT", "length": 469, "header": "tr|A0A8V0YND6-1|A0A8V0YND6_CHICK Computationally mapped isoform of Sestrin 1 OS=Gallus gallus OX=9031 GN=SESN1 PE=3 SV=1 CANONICAL=A0A8V0YH04-1" }, "locus": { "chromosome": "3", "start_pos": 66836755, "end_pos": 66829009, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034303.1", "url": "https://www.ensembl.org/id/ENSGALT00010034303.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020152.1", "url": "https://www.ensembl.org/id/ENSGALP00010020152.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-5628897", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5628897", "resource": "Reactome", "description": "TP53 Regulates Metabolic Genes" }, { "id": "R-GGA-9639288", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9639288", "resource": "Reactome", "description": "Amino acids regulate mTORC1" }, { "id": "R-GGA-9755511", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9755511", "resource": "Reactome", "description": "KEAP1-NFE2L2 pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YH04", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH04" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YH04", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH04" } ], "pmid": "" }, { "name": "fibrillar center", "id": "GO:0001650", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001650", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YH04", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH04" } ], "pmid": "" }, { "name": "GATOR2 complex", "id": "GO:0061700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061700", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YH04", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH04" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YH04", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH04" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 9, "go_terms": [ { "name": "negative regulation of cell growth", "id": "GO:0030308", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030308", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YH04", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH04" } ], "pmid": "" }, { "name": "cellular response to glucose starvation", "id": "GO:0042149", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042149", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YH04", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH04" } ], "pmid": "" }, { "name": "positive regulation of macroautophagy", "id": "GO:0016239", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016239", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YH04", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH04" } ], "pmid": "" }, { "name": "reactive oxygen species metabolic process", "id": "GO:0072593", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072593", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YH04", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH04" } ], "pmid": "" }, { "name": "cellular oxidant detoxification", "id": "GO:0098869", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098869", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YH04", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH04" } ], "pmid": "" }, { "name": "negative regulation of TORC1 signaling", "id": "GO:1904262", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904262", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YH04", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH04" } ], "pmid": "" }, { "name": "regulation of response to reactive oxygen species", "id": "GO:1901031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901031", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YH04", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH04" } ], "pmid": "" }, { "name": "cellular response to leucine starvation", "id": "GO:1990253", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990253", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YH04", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH04" } ], "pmid": "" }, { "name": "cellular response to L-leucine", "id": "GO:0071233", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071233", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YH04", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH04" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "oxidoreductase activity, acting on peroxide as acceptor", "id": "GO:0016684", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016684", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YH04", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH04" } ], "pmid": "" }, { "name": "L-leucine binding", "id": "GO:0070728", "url": 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"url": "https://www.rhea-db.org/rhea/67124" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 376, "end_pos": 378 }, { "start_pos": 75, "end_pos": 77 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", 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"sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YH10-1", "uniprot_ac": "A0A8V0YH10", "uniprot_id": "A0A8V0YH10_CHICK", "mass": { "chemical_mass": 27004.0, "monoisotopic_mass": 27004.0 }, "refseq": { "ac": "XP_004940773", "name": "transmembrane protein 182", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004940773" }, "gene_names": [ { "name": "LOC101750517", "type": "recommended", "evidence": [ { "id": "A0A8V0YH10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH10" } ] }, { "name": "LOC101750517", "type": "synonym", "evidence": [ { "id": "XP_004940773", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004940773" } ] } ], "protein_names": [ { "name": "Transmembrane protein 182", "type": "recommended", "evidence": [ { "id": "A0A8V0YH10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH10/entry#names_and_taxonomy" } ] }, { "name": "transmembrane protein 182", "type": "synonym", "evidence": [ { "id": "XP_004940773", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004940773" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052535.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_004940773.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004940773", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004940773" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YH10", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH10" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LOC101750517", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH10", "locus": {} } ], "crossref": [ { "id": "A0A8V0YH10", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YH10", "database": "AlphaFoldDB", "categories": [] }, { "id": "101750517", "url": "https://www.ncbi.nlm.nih.gov/gene/101750517", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004031", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004031", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR026763", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026763", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:101750517", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:101750517", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "FWRCVFQ", "url": "https://omabrowser.org/oma/group/FWRCVFQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YH10", "url": "https://www.orthodb.org/?gene=A0A8V0YH10", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YQ56", "url": "https://www.orthodb.org/?gene=A0A8V0YQ56", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR32012", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR32012", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR32012:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR32012:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13903", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13903", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_004940773", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004940773", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YH10", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH10", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YH10-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH10-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQ56", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ56", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQ56-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ56-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKAGVASLTAGILGSTAVLLFLLAFGTDYWLLAADTCGVIEDRNSTRQPGEADTLAQAGTQILTFHHEGFFWRCWFFGEGQSATIWTFWYTSQAHPKHCMHGYLFPMPIVLGPFPHPSYDTTAVYRGFWTAFIILAVTAGLVGGLLLVCGVPFVSARSYKVGGGFLIASGSLFLLLIFLFVLWKEFVADFQKYILMERSEVCLQEAPVHVFCGWSFFLAAAGVPLSLLSGLLFFLIGREKTESLE", "length": 245, "header": "tr|A0A8V0YH10-1|A0A8V0YH10_CHICK Isoform 1 of Transmembrane protein 182 OS=Gallus gallus OX=9031 GN=LOC101750517 PE=4 SV=1 CANONICAL=A0A8V0YH10-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YH10-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH10/entry#A0A8V0YH10-1", "sequence": { "sequence": "MKAGVASLTAGILGSTAVLLFLLAFGTDYWLLAADTCGVIEDRNSTRQPGEADTLAQAGTQILTFHHEGFFWRCWFFGEGQSATIWTFWYTSQAHPKHCMHGYLFPMPIVLGPFPHPSYDTTAVYRGFWTAFIILAVTAGLVGGLLLVCGVPFVSARSYKVGGGFLIASGSLFLLLIFLFVLWKEFVADFQKYILMERSEVCLQEAPVHVFCGWSFFLAAAGVPLSLLSGLLFFLIGREKTESLE", "length": 245, "header": "tr|A0A8V0YH10-1|A0A8V0YH10_CHICK Isoform 1 of Transmembrane protein 182 OS=Gallus gallus OX=9031 GN=LOC101750517 PE=4 SV=1 CANONICAL=A0A8V0YH10-1" }, "locus": { "chromosome": "4", "start_pos": 9254953, "end_pos": 9243257, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034309.1", "url": "https://www.ensembl.org/id/ENSGALT00010034309.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020155.1", "url": "https://www.ensembl.org/id/ENSGALP00010020155.1" } ] } }, { "isoform_ac": "A0A8V0YQ56-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH10/entry#A0A8V0YQ56-1", "sequence": { "sequence": "MKAGVASLTAGILGSTAVLLFLLAFGTDYWLLAADTCGVIEDRNSTRQPGEADTLAQAGTQILTFHHEGFFWRCWFFGEGQSATIWTFWYTSQAHPKHCMHGYLFPMPIVLGPFPHPSYDTTAVYRGFWTAFIILAVTAGLVGGLLLVCGVPFVSARSYKVGGGFLIASVYFSCSFSSLCCGRSLWLISKSISSWRGARCACRRLPYMCSVAGPSSLLLLACPCHCSLGSSSS", "length": 233, "header": "tr|A0A8V0YQ56-1|A0A8V0YQ56_CHICK Computationally mapped isoform of Transmembrane protein 182 OS=Gallus gallus OX=9031 GN=LOC101750517 PE=4 SV=1 CANONICAL=A0A8V0YH10-1" }, "locus": { "chromosome": "4", "start_pos": 9254953, "end_pos": 9243289, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034305.1", "url": "https://www.ensembl.org/id/ENSGALT00010034305.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020153.1", "url": "https://www.ensembl.org/id/ENSGALP00010020153.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:101750517", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:101750517", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YH10", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH10" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 44, "end_pos": 46, "annotation": "n_glycosylation_sequon" } ], 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"count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YH11-1", "uniprot_ac": "A0A8V0YH11", "uniprot_id": "A0A8V0YH11_CHICK", "mass": { "chemical_mass": 51757.0, "monoisotopic_mass": 51757.0 }, "refseq": {}, "gene_names": [ { "name": "DNAJB5", "type": "recommended", "evidence": [ { "id": "A0A8V0YH11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH11" } ] } ], "protein_names": [ { "name": "DnaJ heat shock protein family (Hsp40) member B5", "type": "synonym", "evidence": [ { "id": "A0A8V0YH11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH11/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YH11", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH11" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "DNAJB5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH11", "locus": { "chromosome": "Z", "start_pos": 9083500, "end_pos": 9069549, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010011246", "url": "https://www.ensembl.org/id/ENSGALG00010011246" } ] } } ], "crossref": [ { "id": "A0A8V0YH11", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YH11", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000001918", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000001918", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd06257", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06257", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd10747", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd10747", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001623", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001623", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002939", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002939", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008971", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008971", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018253", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018253", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036869", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036869", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051339", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051339", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:427409", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427409", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0Y8L8", "url": "https://www.orthodb.org/?gene=A0A8V0Y8L8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YH11", "url": "https://www.orthodb.org/?gene=A0A8V0YH11", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1BWR7", "url": "https://www.orthodb.org/?gene=E1BWR7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24078", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24078", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24078:SF553", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24078:SF553", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00226", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00226", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01556", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01556", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:E1BWR7", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:E1BWR7", "database": "PRO", "categories": [ "Protein" ] }, { "id": "A0A8V0Y8L8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y8L8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y8L8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y8L8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YH11", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH11", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YH11-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH11-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BWR7", "url": "https://www.uniprot.org/uniprotkb/E1BWR7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BWR7-1", "url": "https://www.uniprot.org/uniprotkb/E1BWR7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGLQIPVVGGAQLHLARHAYNSLSDVLSPISTLLILPCSLSSERSARDGSFCPHLGNGAGEAAAKGRTGHAALTRPGLCLRPTSEENLELGWLWCCCWTVRCGGLCDKNKYSAPGSVAAVMGKDYYKILGIQSGANEDEIKKAYRKMALKYHPDKNKDPNAEEKFKEIAEAYDVLSDPKKRAVYDQYGEEGLKTGGGSSGGSGNTFHYTFHGDPHATFASFFGGSNPFDIFFASSRSRMFNGFDQEDMDIDDDDDPFSAFGRFGFNGINGVHRRHQESLHTRRKVQDPPVIHELKVSLEEIYHGSTKRMKITRRRLNPDGRTMRTEDKILNIVIKRGWKEGTKITFPKEGDATPDNIPADIVFILKDKPHSHFKRDGTNVVYTANISLKEALCGCTVNIPTIDGRVIPLPCNDIIKPGTVKRLRGEGLPFPKAPSQRGDLIVEFKIRFPDRIAPQTRQILKQHLPCS", "length": 467, "header": "tr|A0A8V0YH11-1|A0A8V0YH11_CHICK Isoform 1 of DnaJ heat shock protein family (Hsp40) member B5 OS=Gallus gallus OX=9031 GN=DNAJB5 PE=4 SV=1 CANONICAL=A0A8V0YH11-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Y8L8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH11/entry#A0A8V0Y8L8-1", "sequence": { "sequence": "MTSLAASLRLAACTGTGGSACPAAALPLCCLTKLGLRLPAPALPCRPSCFSGAARRECCLSAFRNKYSAPGSVAAVMGKDYYKILGIQSGANEDEIKKAYRKMALKYHPDKNKDPNAEEKFKEIAEAYDVLSDPKKRAVYDQYGEEGLKTGGGSSGGSGNTFHYTFHGDPHATFASFFGGSNPFDIFFASSRSRMFNGFDQEDMDIDDDDDPFSAFGRFGFNGINGVHRRHQESLHTRRKVQDPPVIHELKVSLEEIYHGSTKRMKITRRRLNPDGRTMRTEDKILNIVIKRGWKEGTKITFPKEGDATPDNIPADIVFILKDKPHSHFKRDGTNVVYTANISLKEALCGCTVNIPTIDGRVIPLPCNDIIKPGTVKRLRGEGLPFPKAPSQRGDLIVEFKIRFPDRIAPQTRQILKQHLPCS", "length": 423, "header": "tr|A0A8V0Y8L8-1|A0A8V0Y8L8_CHICK Computationally mapped isoform of DnaJ heat shock protein family (Hsp40) member B5 OS=Gallus gallus OX=9031 GN=DNAJB5 PE=4 SV=1 CANONICAL=A0A8V0YH11-1" }, "locus": { "chromosome": "Z", "start_pos": 9081847, "end_pos": 9069571, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026853.1", "url": "https://www.ensembl.org/id/ENSGALT00010026853.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015304.1", "url": "https://www.ensembl.org/id/ENSGALP00010015304.1" } ] } }, { "isoform_ac": "A0A8V0YH11-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH11/entry#A0A8V0YH11-1", "sequence": { "sequence": "MGLQIPVVGGAQLHLARHAYNSLSDVLSPISTLLILPCSLSSERSARDGSFCPHLGNGAGEAAAKGRTGHAALTRPGLCLRPTSEENLELGWLWCCCWTVRCGGLCDKNKYSAPGSVAAVMGKDYYKILGIQSGANEDEIKKAYRKMALKYHPDKNKDPNAEEKFKEIAEAYDVLSDPKKRAVYDQYGEEGLKTGGGSSGGSGNTFHYTFHGDPHATFASFFGGSNPFDIFFASSRSRMFNGFDQEDMDIDDDDDPFSAFGRFGFNGINGVHRRHQESLHTRRKVQDPPVIHELKVSLEEIYHGSTKRMKITRRRLNPDGRTMRTEDKILNIVIKRGWKEGTKITFPKEGDATPDNIPADIVFILKDKPHSHFKRDGTNVVYTANISLKEALCGCTVNIPTIDGRVIPLPCNDIIKPGTVKRLRGEGLPFPKAPSQRGDLIVEFKIRFPDRIAPQTRQILKQHLPCS", "length": 467, "header": "tr|A0A8V0YH11-1|A0A8V0YH11_CHICK Isoform 1 of DnaJ heat shock protein family (Hsp40) member B5 OS=Gallus gallus OX=9031 GN=DNAJB5 PE=4 SV=1 CANONICAL=A0A8V0YH11-1" }, "locus": { "chromosome": "Z", "start_pos": 9081847, "end_pos": 9073301, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026849.1", "url": "https://www.ensembl.org/id/ENSGALT00010026849.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015301.1", "url": "https://www.ensembl.org/id/ENSGALP00010015301.1" } ] } }, { "isoform_ac": "E1BWR7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH11/entry#E1BWR7-1", "sequence": { "sequence": "MFKIKLEPLRRSAWSMNVFMKFRNKYSAPGSVAAVMGKDYYKILGIQSGANEDEIKKAYRKMALKYHPDKNKDPNAEEKFKEIAEAYDVLSDPKKRAVYDQYGEEGLKTGGGSSGGSGNTFHYTFHGDPHATFASFFGGSNPFDIFFASSRSRMFNGFDQEDMDIDDDDDPFSAFGRFGFNGINGVHRRHQESLHTRRKVQDPPVIHELKVSLEEIYHGSTKRMKITRRRLNPDGRTMRTEDKILNIVIKRGWKEGTKITFPKEGDATPDNIPADIVFILKDKPHSHFKRDGTNVVYTANISLKEALCGCTVNIPTIDGRVIPLPCNDIIKPGTVKRLRGEGLPFPKAPSQRGDLIVEFKIRFPDRIAPQTRQILKQHLPCS", "length": 382, "header": "tr|E1BWR7-1|E1BWR7_CHICK Computationally mapped isoform of DnaJ heat shock protein family (Hsp40) member B5 OS=Gallus gallus OX=9031 GN=DNAJB5 PE=4 SV=2 CANONICAL=A0A8V0YH11-1" }, "locus": { "chromosome": "Z", "start_pos": 9081847, "end_pos": 9070418, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026851.1", "url": "https://www.ensembl.org/id/ENSGALT00010026851.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015302.1", "url": "https://www.ensembl.org/id/ENSGALP00010015302.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:427409", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427409", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YH11", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH11" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YH11", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH11" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "unfolded protein binding", "id": "GO:0051082", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051082", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YH11", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH11" } ], "pmid": "" }, { "name": "protein-folding chaperone binding", "id": "GO:0051087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051087", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YH11", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH11" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "protein folding", "id": "GO:0006457", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006457", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YH11", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH11" } ], "pmid": "" }, { "name": "response to unfolded protein", "id": "GO:0006986", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006986", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YH11", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH11" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 385, "end_pos": 387, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YH11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH11" }, { "id": "PS50076", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50076" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "J", "eco_id": "ECO_0000259", "start_pos": 124, "end_pos": 188, "start_aa": "Asp", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 385, "end_pos": 387 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YH21-1", "uniprot_ac": "A0A8V0YH21", "uniprot_id": "A0A8V0YH21_CHICK", "mass": { "chemical_mass": 210486.0, "monoisotopic_mass": 210486.0 }, "refseq": { "ac": "XP_416367", "name": "retroelement silencing factor 1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_416367" }, "gene_names": [ { "name": "RESF1", "type": "recommended", "evidence": [ { "id": "A0A8V0YH21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH21" } ] }, { "name": "RESF1", "type": "synonym", "evidence": [ { "id": "XP_416367", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_416367" } ] } ], "protein_names": [ { "name": "Retroelement silencing factor 1", "type": "synonym", "evidence": [ { "id": "A0A8V0YH21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH21/entry#names_and_taxonomy" } ] }, { "name": "retroelement silencing factor 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_416367", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_416367" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_416367.3. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_416367", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_416367" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YH21", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH21" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RESF1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH21", "locus": {} } ], "crossref": [ { "id": "418136", "url": "https://www.ncbi.nlm.nih.gov/gene/418136", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR027866", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027866", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:418136", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418136", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "TYKQMYL", "url": "https://omabrowser.org/oma/group/TYKQMYL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YCC7", "url": "https://www.orthodb.org/?gene=A0A8V0YCC7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YH16", "url": "https://www.orthodb.org/?gene=A0A8V0YH16", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YH21", "url": "https://www.orthodb.org/?gene=A0A8V0YH21", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21604", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21604", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21604:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21604:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15395", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15395", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_416367", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_416367", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YCC7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCC7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YCC7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCC7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YH16", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH16", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YH16-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH16-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YH21", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH21", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YH21-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH21-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKISRKKMKCCTAGGFRISTVDVRKRNHEKMDWNVRPLQNADVQNNLQSQESCYSQMLSNAQAFPQTNALSSENACNYVGNNPVYLPTVNTALPGTSVAIKSFLTSEYSVNQSPPPYVPPAPTLPNQTSRAQGEMTPNSWQNSGRLISSHRKFPLLSSQVSGGNSVPNVLRGPHYATSSSYAVCSQTSQQRSLRTMLHQSNRECINSSKLGCVPQYNTNTSASSQSISVPVNQSSSQYLHSQNNCLPFGTSGQHVQNQIHNSSNQIQFPQSLSQNTATNVHLPQYAPNQMGSGAPSGCSAPSLLPANYDSKTVAQPLLGAQQAVHNVFNKYPLQSCPSDKKNASGFNSVQQYSVKHQLGEVSQGVRNGYNSSGNLTVNQLFSEKSVPPTDVSSELYDIMQGVVPFSSTDASQPLCDPVSVQERQTTSSVNVPANSQTSLAREDKRKMTSDTLAWETQRLQVIKRKCALLERMHQYRRKFFTSKCDKSTSTLPVSYENALSNRLPQMPKQNVVSSLSQAVRTASQEHSILGSSLEERNDRNITGDSRGLEVTQGNHQVEQGSLSSGPLPIPSHSELTALLNNPENSSMLEQKNALASPQKMLTSLNAASCHSQPNRSSGDASASVEGYPENSAFLQFVLSSTNMLKEKKAGTIADNILTNLLSNEKQHVDVTGLGGSLLKDTSGKGDLVSMVHTHAPVSEVMESNVNKFHGDVAQKKMQFTENPCFKQNNGNYSLEELNACLGLWKKQGPEPVSVQNSQLNESTAANQISPLPHSQNTTNKREQGNLLVSTDVTVLPLTTTSIGQKHDALSCNLIKGLELQIAVVSPLVLSNQRAQSEQLDKCPTSADKTYPVIDTGSICSMQEEGKNVLTVVNTDKRTMESVSSPDDCILIQMEDLCSQQTKSADGKRIVENSMNANDSCGKNERKLSQATRDAEENLQNKLLPESGQNFSSKTFQEDIKDHDGKQAVLETQNNTPTAVIEEQMFHIASVCSLVEGDKSYNPQIASMFSSVPQTHAFNSGTSSEENSSDPRQKEQLMKLNKNDLRENTSQLETLLQKALRESSEVDKILNSTVTSHSKKESSGMLPNTVTTSDQKKPVNLSFRYPENDLGILASINQELARNSLDSLVSITAETNAFTVTTCSSKENVTSTKKSVEELHIFGAEPITCLDNQLTELMKEFPFGIEGADILTKEPARNNSVTEQREDQAQKETHVSAKKTDSKNQIDELQIAQLNSDRVQELFPEKKLCSSTENSVAMSQQSEKTSTQEDSLESSVQPSQSLCKEKENPQSPSSSGNKEVCSLTGCLSASGEMSQSSCKRRTSVSDKNDEQLSEAENPNSAGRQENNSKSDAIIKNNSVVENPPICENVQNSIQKNKEDVCKYISVTNKKSKMNNEPKPLSPQLEKNGPLNSSEKQDVNSSKSGNKKEEMQESGRTPLLKKEFHSDKKDHQKISEGELPEKGGCTGVDSVMKSSEKEKIFKMKSLSKDKTRTDLAPKSQRDLHKYTKSENVAIKRTEVCQGQERKICDNNSGKEQNCKKRNVGVNTERKAKLSPEIKREKLNSYHAEAMKFPNLGIRDLKSSNYTFSQRNSIKAHPPQEESYKRKRKDNLIGKTSSKKTKVEDERLKQSETKNSKRHSYDRKINTDKTKKLSGENVWKPKNSLADRSMLKLQRIRGLSTISKNHFSNKEKHLDGQNKDKCSEKMFSDKNGLYLNRRTNRLKLHLQKEPKKHYLNRVAFKRTAQERIFLTKLETSPVRPVLHVKSQVSPHSLDSKRDASLSENEKPRKRQVLEFKLCPEILFRNSATDDESLAAKNFLEKEKTTVAGVKSKKEDWLKYDSVKQKKLKEIFTAEDCIPLDTAIQILEGDEQALHIPIKDSKQMFQTYKKMYLEKKMEKPG", "length": 1897, "header": "tr|A0A8V0YH21-1|A0A8V0YH21_CHICK Isoform 1 of Retroelement silencing factor 1 OS=Gallus gallus OX=9031 GN=RESF1 PE=4 SV=1 CANONICAL=A0A8V0YH21-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YCC7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH21/entry#A0A8V0YCC7-1", "sequence": { "sequence": "MHLPFIQNRISTVDVRKRNHEKMDWNVRPLQNADVQNNLQSQESCYSQMLSNAQAFPQTNALSSENACNYVGNNPVYLPTVNTALPGTSVAIKSFLTSEYSVNQSPPPYVPPAPTLPNQTSRAQGEMTPNSWQNSGRLISSHRKFPLLSSQVSGGNSVPNVLRGPHYATSSSYAVCSQTSQQRSLRTMLHQSNRECINSSKLGCVPQYNTNTSASSQSISVPVNQSSSQYLHSQNNCLPFGTSGQHVQNQIHNSSNQIQFPQSLSQNTATNVHLPQYAPNQMGSGAPSGCSAPSLLPANYDSKTVAQPLLGAQQAVHNVFNKYPLQSCPSDKKNASGFNSVQQYSVKHQLGEVSQGVRNGYNSSGNLTVNQLFSEKSVPPTDVSSELYDIMQGVVPFSSTDASQPLCDPVSVQERQTTSSVNVPANSQTSLAREDKRKMTSDTLAWETQRLQVIKRKCALLERMHQYRRKFFTSKCDKSTSTLPVSYENALSNRLPQMPKQNVVSSLSQAVRTASQEHSILGSSLEERNDRNITGDSRGLEVTQGNHQVEQGSLSSGPLPIPSHSELTALLNNPENSSMLEQKNALASPQKMLTSLNAASCHSQPNRSSGDASASVEGYPENSAFLQFVLSSTNMLKEKKAGTIADNILTNLLSNEKQHVDVTGLGGSLLKDTSGKGDLVSMVHTHAPVSEVMESNVNKFHGDVAQKKMQFTENPCFKQNNGNYSLEELNACLGLWKKQGPEPVSVQNSQLNESTAANQISPLPHSQNTTNKREQGNLLVSTDVTVLPLTTTSIGQKHDALSCNLIKGLELQIAVVSPLVLSNQRAQSEQLDKCPTSADKTYPVIDTGSICSMQEEGKNVLTVVNTDKRTMESVSSPDDCILIQMEDLCSQQTKSADGKRIVENSMNANDSCGKNERKLSQATRDAEENLQNKLLPESGQNFSSKTFQEDIKDHDGKQAVLETQNNTPTAVIEEQMFHIASVCSLVEGDKSYNPQIASMFSSVPQTHAFNSGTSSEENSSDPRQKEQLMKLNKNDLRENTSQLETLLQKALRESSEVDKILNSTVTSHSKKESSGMLPNTVTTSDQKKPVNLSFRYPENDLGILASINQELARNSLDSLVSITAETNAFTVTTCSSKENVTSTKKSVEELHIFGAEPITCLDNQLTELMKEFPFGIEGADILTKEPARNNSVTEQREDQAQKETHVSAKKTDSKNQIDELQIAQLNSDRVQELFPEKKLCSSTENSVAMSQQSEKTSTQEDSLESSVQPSQSLCKEKENPQSPSSSGNKEVCSLTGCLSASGEMSQSSCKRRTSVSDKNDEQLSEAENPNSAGRQENNSKSDAIIKNNSVVENPPICENVQNSIQKNKEDVCKYISVTNKKSKMNNEPKPLSPQLEKNGPLNSSEKQDVNSSKSGNKKEEMQESGRTPLLKKEFHSDKKDHQKISEGELPEKGGCTGVDSVMKSSEKEKIFKMKSLSKDKTRTDLAPKSQRDLHKYTKSENVAIKRTEVCQGQERKICDNNSGKEQNCKKRNVGVNTERKAKLSPEIKREKLNSYHAEAMKFPNLGIRDLKSSNYTFSQRNSIKAHPPQEESYKRKRKDNLIGKTSSKKTKVEDERLKQSETKNSKRHSYDRKINTDKTKKLSGENVWKPKNSLADRSMLKLQRIRGLSTISKNHFSNKEKHLDGQNKDKCSEKMFSDKNGLYLNRRTNRLKLHLQKEPKKHYLNRVAFKRTAQERIFLTKLETSPVRPVLHVKSQVSPHSLDSKRDASLSENEKPRKRQVLEFKLCPEILFRNSATDDESLAAKNFLEKEKTTVAGVKSKKEDWLKYDSVKQKKLKEIFTAEDCIPLDTAIQILEGDEQALHIPIKDSKQMFQTYKKMYLEKKMEKPG", "length": 1889, "header": "tr|A0A8V0YCC7-1|A0A8V0YCC7_CHICK Computationally mapped isoform of Retroelement silencing factor 1 OS=Gallus gallus OX=9031 GN=RESF1 PE=4 SV=1 CANONICAL=A0A8V0YH21-1" }, "locus": { "chromosome": "1", "start_pos": 59371771, "end_pos": 59360996, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026863.1", "url": "https://www.ensembl.org/id/ENSGALT00010026863.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015308.1", "url": "https://www.ensembl.org/id/ENSGALP00010015308.1" } ] } }, { "isoform_ac": "A0A8V0YH16-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH21/entry#A0A8V0YH16-1", "sequence": { "sequence": "MSRISTVDVRKRNHEKMDWNVRPLQNADVQNNLQSQESCYSQMLSNAQAFPQTNALSSENACNYVGNNPVYLPTVNTALPGTSVAIKSFLTSEYSVNQSPPPYVPPAPTLPNQTSRAQGEMTPNSWQNSGRLISSHRKFPLLSSQVSGGNSVPNVLRGPHYATSSSYAVCSQTSQQRSLRTMLHQSNRECINSSKLGCVPQYNTNTSASSQSISVPVNQSSSQYLHSQNNCLPFGTSGQHVQNQIHNSSNQIQFPQSLSQNTATNVHLPQYAPNQMGSGAPSGCSAPSLLPANYDSKTVAQPLLGAQQAVHNVFNKYPLQSCPSDKKNASGFNSVQQYSVKHQLGEVSQGVRNGYNSSGNLTVNQLFSEKSVPPTDVSSELYDIMQGVVPFSSTDASQPLCDPVSVQERQTTSSVNVPANSQTSLAREDKRKMTSDTLAWETQRLQVIKRKCALLERMHQYRRKFFTSKCDKSTSTLPVSYENALSNRLPQMPKQNVVSSLSQAVRTASQEHSILGSSLEERNDRNITGDSRGLEVTQGNHQVEQGSLSSGPLPIPSHSELTALLNNPENSSMLEQKNALASPQKMLTSLNAASCHSQPNRSSGDASASVEGYPENSAFLQFVLSSTNMLKEKKAGTIADNILTNLLSNEKQHVDVTGLGGSLLKDTSGKGDLVSMVHTHAPVSEVMESNVNKFHGDVAQKKMQFTENPCFKQNNGNYSLEELNACLGLWKKQGPEPVSVQNSQLNESTAANQISPLPHSQNTTNKREQGNLLVSTDVTVLPLTTTSIGQKHDALSCNLIKGLELQIAVVSPLVLSNQRAQSEQLDKCPTSADKTYPVIDTGSICSMQEEGKNVLTVVNTDKRTMESVSSPDDCILIQMEDLCSQQTKSADGKRIVENSMNANDSCGKNERKLSQATRDAEENLQNKLLPESGQNFSSKTFQEDIKDHDGKQAVLETQNNTPTAVIEEQMFHIASVCSLVEGDKSYNPQIASMFSSVPQTHAFNSGTSSEENSSDPRQKEQLMKLNKNDLRENTSQLETLLQKALRESSEVDKILNSTVTSHSKKESSGMLPNTVTTSDQKKPVNLSFRYPENDLGILASINQELARNSLDSLVSITAETNAFTVTTCSSKENVTSTKKSVEELHIFGAEPITCLDNQLTELMKEFPFGIEGADILTKEPARNNSVTEQREDQAQKETHVSAKKTDSKNQIDELQIAQLNSDRVQELFPEKKLCSSTENSVAMSQQSEKTSTQEDSLESSVQPSQSLCKEKENPQSPSSSGNKEVCSLTGCLSASGEMSQSSCKRRTSVSDKNDEQLSEAENPNSAGRQENNSKSDAIIKNNSVVENPPICENVQNSIQKNKEDVCKYISVTNKKSKMNNEPKPLSPQLEKNGPLNSSEKQDVNSSKSGNKKEEMQESGRTPLLKKEFHSDKKDHQKISEGELPEKGGCTGVDSVMKSSEKEKIFKMKSLSKDKTRTDLAPKSQRDLHKYTKSENVAIKRTEVCQGQERKICDNNSGKEQNCKKRNVGVNTERKAKLSPEIKREKLNSYHAEAMKFPNLGIRDLKSSNYTFSQRNSIKAHPPQEESYKRKRKDNLIGKTSSKKTKVEDERLKQSETKNSKRHSYDRKINTDKTKKLSGENVWKPKNSLADRSMLKLQRIRGLSTISKNHFSNKEKHLDGQNKDKCSEKMFSDKNGLYLNRRTNRLKLHLQKEPKKHYLNRVAFKRTAQERIFLTKLETSPVRPVLHVKSQVSPHSLDSKRDASLSENEKPRKRQVLEFKLCPEILFRNSATDDESLAAKNFLEKEKTTVAGVKSKKEDWLKYDSVKQKKLKEIFTAEDCIPLDTAIQILEGDEQALHIPIKDSKQMFQTYKKMYLEKKMEKPG", "length": 1883, "header": "tr|A0A8V0YH16-1|A0A8V0YH21_CHICK Computationally mapped isoform of Retroelement silencing factor 1 OS=Gallus gallus OX=9031 GN=RESF1 PE=4 SV=1 CANONICAL=A0A8V0YH21-1" }, "locus": { "chromosome": "1", "start_pos": 59370480, "end_pos": 59360996, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026860.1", "url": "https://www.ensembl.org/id/ENSGALT00010026860.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015306.1", "url": "https://www.ensembl.org/id/ENSGALP00010015306.1" } ] } }, { "isoform_ac": "A0A8V0YH21-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH21/entry#A0A8V0YH21-1", "sequence": { "sequence": "MKISRKKMKCCTAGGFRISTVDVRKRNHEKMDWNVRPLQNADVQNNLQSQESCYSQMLSNAQAFPQTNALSSENACNYVGNNPVYLPTVNTALPGTSVAIKSFLTSEYSVNQSPPPYVPPAPTLPNQTSRAQGEMTPNSWQNSGRLISSHRKFPLLSSQVSGGNSVPNVLRGPHYATSSSYAVCSQTSQQRSLRTMLHQSNRECINSSKLGCVPQYNTNTSASSQSISVPVNQSSSQYLHSQNNCLPFGTSGQHVQNQIHNSSNQIQFPQSLSQNTATNVHLPQYAPNQMGSGAPSGCSAPSLLPANYDSKTVAQPLLGAQQAVHNVFNKYPLQSCPSDKKNASGFNSVQQYSVKHQLGEVSQGVRNGYNSSGNLTVNQLFSEKSVPPTDVSSELYDIMQGVVPFSSTDASQPLCDPVSVQERQTTSSVNVPANSQTSLAREDKRKMTSDTLAWETQRLQVIKRKCALLERMHQYRRKFFTSKCDKSTSTLPVSYENALSNRLPQMPKQNVVSSLSQAVRTASQEHSILGSSLEERNDRNITGDSRGLEVTQGNHQVEQGSLSSGPLPIPSHSELTALLNNPENSSMLEQKNALASPQKMLTSLNAASCHSQPNRSSGDASASVEGYPENSAFLQFVLSSTNMLKEKKAGTIADNILTNLLSNEKQHVDVTGLGGSLLKDTSGKGDLVSMVHTHAPVSEVMESNVNKFHGDVAQKKMQFTENPCFKQNNGNYSLEELNACLGLWKKQGPEPVSVQNSQLNESTAANQISPLPHSQNTTNKREQGNLLVSTDVTVLPLTTTSIGQKHDALSCNLIKGLELQIAVVSPLVLSNQRAQSEQLDKCPTSADKTYPVIDTGSICSMQEEGKNVLTVVNTDKRTMESVSSPDDCILIQMEDLCSQQTKSADGKRIVENSMNANDSCGKNERKLSQATRDAEENLQNKLLPESGQNFSSKTFQEDIKDHDGKQAVLETQNNTPTAVIEEQMFHIASVCSLVEGDKSYNPQIASMFSSVPQTHAFNSGTSSEENSSDPRQKEQLMKLNKNDLRENTSQLETLLQKALRESSEVDKILNSTVTSHSKKESSGMLPNTVTTSDQKKPVNLSFRYPENDLGILASINQELARNSLDSLVSITAETNAFTVTTCSSKENVTSTKKSVEELHIFGAEPITCLDNQLTELMKEFPFGIEGADILTKEPARNNSVTEQREDQAQKETHVSAKKTDSKNQIDELQIAQLNSDRVQELFPEKKLCSSTENSVAMSQQSEKTSTQEDSLESSVQPSQSLCKEKENPQSPSSSGNKEVCSLTGCLSASGEMSQSSCKRRTSVSDKNDEQLSEAENPNSAGRQENNSKSDAIIKNNSVVENPPICENVQNSIQKNKEDVCKYISVTNKKSKMNNEPKPLSPQLEKNGPLNSSEKQDVNSSKSGNKKEEMQESGRTPLLKKEFHSDKKDHQKISEGELPEKGGCTGVDSVMKSSEKEKIFKMKSLSKDKTRTDLAPKSQRDLHKYTKSENVAIKRTEVCQGQERKICDNNSGKEQNCKKRNVGVNTERKAKLSPEIKREKLNSYHAEAMKFPNLGIRDLKSSNYTFSQRNSIKAHPPQEESYKRKRKDNLIGKTSSKKTKVEDERLKQSETKNSKRHSYDRKINTDKTKKLSGENVWKPKNSLADRSMLKLQRIRGLSTISKNHFSNKEKHLDGQNKDKCSEKMFSDKNGLYLNRRTNRLKLHLQKEPKKHYLNRVAFKRTAQERIFLTKLETSPVRPVLHVKSQVSPHSLDSKRDASLSENEKPRKRQVLEFKLCPEILFRNSATDDESLAAKNFLEKEKTTVAGVKSKKEDWLKYDSVKQKKLKEIFTAEDCIPLDTAIQILEGDEQALHIPIKDSKQMFQTYKKMYLEKKMEKPG", "length": 1897, "header": "tr|A0A8V0YH21-1|A0A8V0YH21_CHICK Isoform 1 of Retroelement silencing factor 1 OS=Gallus gallus OX=9031 GN=RESF1 PE=4 SV=1 CANONICAL=A0A8V0YH21-1" }, "locus": { "chromosome": "1", "start_pos": 59397951, "end_pos": 59360996, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026869.1", "url": "https://www.ensembl.org/id/ENSGALT00010026869.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015311.1", "url": "https://www.ensembl.org/id/ENSGALP00010015311.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:418136", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418136", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0ABK0LW17-1", "protein_name": "Retroelement silencing factor 1", "gene_name": "Resf1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSWNAKPENAVAKPPKFSKTQSSILQQFLMTSTTSQSSFSYPAHNQEACMYSSNSNSVSQPLLSGRNYMTPQTQISVSNMPSRTIVTSQSSMEGVVCTNVKGPQQPNHNLQTVSSGVMQNVWFGSSVKNFMPSHTEATISHNPDGRTNMPYMQTPQSQLVTSDTYSMQLQMVPFNSGKVPVAYQGNQGLNHFIPDQLADWTQYTSSELTYPEYRPPLKQYSRILPATTSLQVKNNPLPTYTQALQSKHSAPLSSHPYAAETSKRLSALPYSCRYGSQHVQNTQPVSKHLPMEVPQSPEVHSSEKKQDSYRGFKQQWQNPNESFTIGKFSDLKINAKQSYSDTVRSSGDGVQALVQNNQEKRKYPYSPSTNQVIDTNATKEKLARDIKSLVEIKKKFTELARKIKINKSLLMAAGCSKTANTSYTEPIQHSEFSAKEMSAKNGNDCSMELLATCLSLWKNQPPKTTEENVPKPLEEKQCNTSRISTTVVGSSHPTNEVHVKSFCSGVGNSQKLLSSSQTILSVLTPSGESSGVAVGKGTELQIAVVSPLVLADTNPLPGKELAPEVLPEPPYPVVKEGSICSLQHQQAETAALPFHITGVVADSNLSVEMSLPAQKEKQHKPTQGDPDIADHGLGKLSPLGTEAVPNSVDSTTVSGPMLQIESICSLAEGDVSYNSQIAEIFNSVQNEPEKPSPNQVINNQQEQVDGTTENKDFSLQKDKKYIRYTYVPREITEQPEVLQPEEPASCEYVEANTETIEESGRECSGGKESTAEDVCSPAGFQQDPHPQETDSLSNKSAHCLPAVNEINDESEPVSYLHDQLSELLKEFPYGIETVSRHEVSVDQKKTHKILENETGDKTSNVFGDSTDQIKITVLNSEQIKELFPEEDQPCDLDKLAEPEGKNVAEVKSPCDSQVPREESHDFGMLDPEKDKIHCCALGWLSMVYEGVPKCHCSSNEEKGKDQCLDMNSCKQGEQPCNNGITIFEINPVSNNPKTPLTQAAEKGHFSEMHGDKTKGSKTKDSREEQQHFSAKCYKKDKDNLKMRHDSSLKMEQKLKNTSSECDRLNPSKSSKIATPEILHVKTSNSDKNMSFFKQASQESLQRKPTSQDSNPVKAPVELPSNTDPCRRNTSLVQFVSPEKKKLKFKAGGSRLKYFEKRKTDNMIIPDVEIKKKKYEKQEQNKNAGETLKLCSALRESNERASVQENAIPSPESSDSKGSSLKSTRVITVQEYLQRRKDKHVTGSDASGNICVENVLCNSEHMKTSKDSAEISWEKSADGQSIRAETSKEPGHNSTIHGKAFKIHHSEVSRTHSVSSNSKGKQPDKIYKARTSNEHSQVPLQVKEQRKQYLNRVAFKCTERESICLTKLDSASKKLSTEKKESEAHTLKTKNIDKPSMLEFKLCPDVLLKNTSSVDKQDEPEPKKEKAPVQVKLLV", "length": 1434 }, "evidence": [ { "id": "A0A8V0YH21", "url": "https://omabrowser.org/oma/group/A0A8V0YH21/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "I3LJU6-1", "protein_name": "Retroelement silencing factor 1", "gene_name": "RESF1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MNWNAKPESVTLPPQYPRKQTSFLEQALVSTLTTSQSPLNHPGSNQEACLFLSNSNPVSQPLLNNRNYKTPQQIPISDMHSGTIVTSQTSVERITYTNVKGPKQLNQDLQVSSGVTQDMWLNSPMRNSMLSHTGATVSHQTGFGTNPPNVHALQNQFVTSDTYSMQLQMMPSNSGRAPITYQDNPRLNPPLSEQQVDWPQQCASSGLAYPNYRPLPKQYGYSSRSFVQGPTLPKQNTMSAGSLQVKNSPSPNPVLPLQSKQIATIPSYQYAVTHTDERPPPPYDCRYASQPLQSIQHVVKRSSMDGPQTQEMYLPEMGKDFCRGFQQQWQNSNENFSMMGNTCNLKVNTNVGQPFNRPVRSSLDSVQALGQNTQEKRVDSGNLTSNQVLDTRATKEKLVRDIKTLVEIKKKFSDLARKIKINKSLLMAAGCIKTTSSPYSNTAQNSQFSLKQTAKVQCGPQVTIVTPETMENKSPIVMESSEVANKTHSPSNSNLQDRHFNQVSSVLLNSVPSEKLPIPEQLRDLKVVTSSKMSTVEIPHATSNNIQFSSGNLVNSTKNVPAHSETTPLPQFMTFEEYISKHPNKNRLVLSLLAPGGKIERKLLKDTIETVKDSKMRSSDVNPNTTNTGNLMNLKTVETASACNINAKISDNSSGFEHKSLNGMSSKSDGHFSMELLATCLSLWKKQPSEPTVEKQSNESKTNRAAAGVSKPVEVCETSPFSAVGNSQNKVTSSSQETVLSMVTQNFESSGSTTTKGIAVVSPLILSDVKTLSVKGITPEALPETAYPVIKEGSICSLQNKLENTAALKVSVHEPVTSTTSTKIFPLIQKEKQNESTNANSEGTPNTSQGKYNETEPDVQCPVSDQQTSYVSKDSDDVHSDVLQIDNICSLVEGDTSYNSQIAKIFNLHPLEKVEQQKPLLSHQVMSSRQQNEQVDVTESKDFDCQKDNFVQCTDTSHETIDQSMLLHPPESSSLKYTEAKRGIPEESSLEQITEIESLADDVVSPAAIQQDNCPQETDMSCSYTAQDPTKNELLDDETSILYLQDQLSELLKEFPYGIEPVNMHEGCAVQQMADPISKPQTCEHTGCDSKDSTDQIQITILNSEQMKELFPEQDGPPNEVDRLTELQEEKPVTKEGNQCDPQARTIEESCESVVLDSEKDDVRCCALGWLSMVYEGVPQCQCNSIKNSASKEEKGKDPCSLEANANSYKRGERTSDGDDSVTFENPPDNQKLPLTFPVEEKHFPETEGGRNINDKSETEQNSSLRTEQELPGQFLCKGGKRRDPLQRHKKKPLQFHEVTFQSTNKTIKICQESLQRKLMAQNLRPLKPKMGFLTSKNKDLHVKNASLVQSITPEKRKLKAAGSKHKVLEKRKLDDGSIHDSEVKKKKYDKQEQNKNVGSGTFKLYNFSTPSERAMTKEKTVSNVKSSGSKDGSSKINRVLTAKEYLARQKHKEAVSGKTLKKNCLKNLPCDSQYKKSSKLPVRVGSCGKSSERQNSNVQTTKESLPISSNHGKSLKIHHSRDSKTHILRNIKGTVGGKQPDKMWIDKTKSDKNVNNVNNEAEFSQMSSQAKDQRKTYLNRVGFKCTERERICLTKLDGSPRKLNKEKRPENKPKNHVPGKDTSEKLSMLEFKLCPDGLFKNPNPVEDQKDLQPCPMKEQAPVQVSGIKSTKEDWLKCVTEEKKIPEPNQEIDDVLANSRLSKRSFSADGYETQQNQVKDSKAMFQTYKKMYMEKRSRSLGSSPLE", "length": 1746 }, "evidence": [ { "id": "A0A8V0YH21", "url": "https://omabrowser.org/oma/group/A0A8V0YH21/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q5DTW7-1", "protein_name": "Retroelement silencing factor 1", "gene_name": "Resf1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNWNTKQENVPKPPPYSKTQSSILQHFLMTSTTSQSSFNYSPHNQEASQTSFNYSLHNQEACMYSGNSNSVSQPLLSGRNYITPQTQISVSNMPTRTIVASQSSMERVVSTNGKGPQQPNHNLQTVSSGIMQNVWLPSHTEATISHNPDGGTNMPYMHPPQNQLVTSDTYSMQLQMAPLHSGKVPMTHQGSQGLNHFIPDQLVDWTQYTSNELSYPEYRPPPKQYSYILPATTSLQVKNNQLPTYTQSLQSKHSVPLSSHQYAAEASKRLSALPYSCRYENQHVQNAQPVSKHLPMEVPQSSEVHSSEKKKDTYRGFKQQWQNPNEKVSIGQFSEVKINIKQPYSESVRPSGDGVQALVQNNQEKRKYTYNPNTNQVIDTNATKEKLVRDIKSLVEIKKKFSELARKIKINKSLLMAAGCSKTANTSYTEPIQHSEFSAKEMSAKNGNDCSMELLATCLSLWKNQPSKTTEENVPKPLEEKQCNTSRISTTVVGSANPTNEVHVKSLCSGVGNSQKMMSSSQTVLPVLIPSCESSGVAVGKGTELQIAVVSPLVLSDTNTLPGKDSVPEVLPETLYPVVKEGSVCSLQTQPTETVALPFDVIGAVASNNISAEIPLPVDKEKQHKPIQGDPDIADSSLGKHSPLGTEVLPKPMDSTIVSGPMLQIESICSLAEGDVSYNSQIAEIFNSVQTEPQKPSPNQVIDSQQEQVYDTTENKDFSLQKDKCVQCTDVPHEVPEQPEPLQPEEPASSEYVEANREATEESCREYTGRKESTAKDVCLPAAIQQDPHPRETDMFSKSDHSLPAINEINDESEPISYLHDQLSELLKEFPYGIETFNRHEVSLDQQKTHKIVENQTGGKTSNVSGDSTDQIKITVLNSEQIKELFPEDDQPCDKLAEPENKEIVAEVKSPCDSQIPREESHDLGMLDPEKDKIHCCALGWLSMVYEGVPQCHCSSTEKKEKDQCLDINSSKQGEQPCNSGITIFEINPVSNNSKTPLTQATEEGHFSAVHGEKTKASKTKDNREGQELACHFSAKCYKKDKKGNFKIRHDTSLKMEQKLKNISSKCDIPNPSKCNKIAAPEILHVTTSNSAKNMPFSKQASQESLQKKHTSQDLGPVKAPIELSSNTDPCRSNTSSVQSVSPEKKKLKFKAGGSRLKYFEKRKTDHVIIPDVEIKKKKYEKQEQNKNAGDTLKLCSILTESNERASVQEKTVPSPESSDPKGSSSKSTRVITVQEYLQRQKDKQITGNNASRNICVETVLCDSGHTKTSKHSAAVSWGKLVEGQSISAETAKELEHNSSSHGKDFKIHHSEASRTHSVSNNNKGKFDGKQPDKMFKNKTSMNNESNQMPLQVKEQRKQYLNRVAFKCTERESICLTKLDSASKKLSIEKKSGEYTSKTKDTDKPSMLEFKLCPDVLLKNTSTVDKQDCPGPGPEKEQAPVQVSGIKSTKEDWLKCIPTRTKMPESSQRDSADSRLSKRSLSADEFEILQNPVKESNIMFRTYKKMYLEKRSRSLGSSPVK", "length": 1521 }, "evidence": [ { "id": "A0A8V0YH21", "url": "https://omabrowser.org/oma/group/A0A8V0YH21/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9HCM1-1", "protein_name": "Retroelement silencing factor 1", "gene_name": "RESF1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNWNEKPKSATLPPLYPKSQPPFLHQSLINQITTTSQSSFSYPGSNQEACMYPGNSNPISQPLLNIQNYPQQISVSDMHNGTVVASHTSVERITYANVNGPKQLTHNLQMSSGVTQNVWLNSPMRNPVHSHIGATVSHQTDFGANVPNMPALQSQLITSDTYSMQMQMIPSNSTRLPVAYQGNQGLNQSFSEQQVDWTQQCISKGLTYPDYRPPPKLYRYSPQSFLPDSTIQKQNFIPHTSLQVKNSQLLNSVLTLPSRQTSAVPSQQYATQTDKRPPPPPYNCRYGSQPLQSTQHITKHLSMEVPQSREMLSSEIRTSFQQQWQNPNENVSTIGNFTNLKVNTNSKQPFNSPIRSSVDGVQTLAQTNEEKIMDSCNPTSNQVLDTSVAKEKLVRDIKTLVEIKQKFSELARKIKINKDLLMAAGCIKMTNTSYSEPAQNSKLSLKQTAKIQSGPQITPVMPENAERQTPTVVESAETNKTQCMLNSDIQEVNCRRFNQVDSVLPNPVYSEKRPMPDSSHDVKVLTSKTSAVEMTQAVLNTQLSSENVTKVEQNSPAVCETISVPKSMSTEEYKSKIQNENMLLLALLSQARKTQKTVLKDANQTIQDSKPDSCEMNPNTQMTGNQLNLKNMETPSTSNVSGRVLDNSFCSGQESSTKGMPAKSDSSCSMEVLATCLSLWKKQPSDTAKEKECDKLRTNTTAVGISKPANIHVKSPCSVVGNSNSQNKISNPSQQTALSMVMHNYESSGINITKGTELQIAVVSPLVLSEVKTLSVKGITPAVLPETVYPVIKEGSVCSLQNQLAENAKATAALKVDVSGPVASTATSTKIFPLTQKEKQNESTNGNSEVTPNVNQGKHNKLESAIHSPMNDQQISQESRNSTVVSSDTLQIDNICSLVEGDTSYNSQIAKIFSSLPLKMVEPQKPSLPNQQGIGSREPEKQLDNTTENKDFGFQKDKPVQCTDVSHKICDQSKSEPPLESSFNNLETNRVILEKSSLEHATEKSTANDTCSSAAIQEDIYPQEIDASSNYTPQDPARNEIHSDKAPVLYLHDQLSELLKEFPYGIEAVNTREGSVGQQTTYQTSEDQTADKTSSDSKDPADQIQITILSSEQMKEIFPEQDDQPYVVDKLAEPQKEEPITEVVSQCDLQAPAAGQSRDSVILDSEKDDIHCCALGWLSMVYEGVPQCQCNSIKNSSSEEEKQKEQCSPLDTNSCKQGERTSDRDVTVVQFKSLVNNPKTPPDGKSHFPELQDDSRKDTPKTKHKSLPRTEQELVAGQFSSKCDKLNPLQNHKRKKLRFHEVTFHSSNKMTASYEQASQETRQKKHVTQNSRPLKTKTAFLPNKDVYKKHSSLGQSLSPEKIKLKLKSVSFKQKRKLDQGNVLDMEVKKKKHDKQEQKGSVGATFKLGDSLSNPNERAIVKEKMVSNTKSVDTKASSSKFSRILTPKEYLQRQKHKEALSNKASKKICVKNVPCDSEHMRPSKLAVQVESCGKSNEKHSSGVQTSKESLNGLTSHGKNLKIHHSQESKTYNILRNVKEKVGGKQPDKIWIDKTKLDKLTNISNEAQFSQMPPQVKDQKKLYLNRVGFKCTERESISLTKLESSPRKLHKDKRQENKHKTFLPVKGNTEKSNMLEFKLCPDILLKNTNSVEERKDVKPHPRKEQAPLQVSGIKSTKEDWLKFVATKKRTQKDSQERDNVNSRLSKRSFSADGFEMLQNPVKDSKEMFQTYKQMYLEKRSRSLGSSPVK", "length": 1747 }, "evidence": [ { "id": "A0A8V0YH21", "url": "https://omabrowser.org/oma/group/A0A8V0YH21/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YH21", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH21" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "histone methyltransferase binding", "id": "GO:1990226", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990226", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YH21", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH21" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1026, "end_pos": 1028, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1047, "end_pos": 1049, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1070, "end_pos": 1072, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1099, "end_pos": 1101, "annotation": "n_glycosylation_sequon" }, { "start_pos": 111, "end_pos": 113, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1147, "end_pos": 1149, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1197, "end_pos": 1199, "annotation": "n_glycosylation_sequon" }, { "start_pos": 126, "end_pos": 128, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1345, "end_pos": 1347, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1355, "end_pos": 1357, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1410, "end_pos": 1412, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1418, "end_pos": 1420, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1528, "end_pos": 1530, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1582, "end_pos": 1584, "annotation": "n_glycosylation_sequon" }, { 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"count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YH39-1", "uniprot_ac": "A0A8V0YH39", "uniprot_id": "A0A8V0YH39_CHICK", "mass": { "chemical_mass": 59824.0, "monoisotopic_mass": 59824.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Uncharacterized protein", "type": "synonym", "evidence": [ { "id": "A0A8V0YH39", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH39/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YH39", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH39" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH39", "locus": {} } ], "crossref": [ { "id": "A0A8V0YH39", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YH39", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR053270", "url": "https://www.ebi.ac.uk/interpro/entry/IPR053270", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR48195", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48195", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR48195:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48195:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YH39", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH39", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YH39-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH39-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTFLNNFMGWFGWGKASPISEVLPGHIPGFLGSPYHGIACIIEKWGPLRDAGNVQESPARLAEYFSSLNKNVLTTRERQLAASTVAWPLLMALNRLNITEGVLTDENQLLRDRVEELERQVAILRGKKPNPIIPVQKIRNISLEITGDPIQESPHELDSENESTKKSDLEAPLELDPFEIRPVVTQKTKKTQDRPAGLPPDQWPPAQSTLHVTARPYTAAELMDLVQRFRQRPRESVPAWLLRLYDMGAESVVVNGPEISKLASITTHPALRQRLYAAVQHNEENHSLIAWLMAACRVTWANKTDIPLNTGLWSSMEDLQNYIRELGMKEAIYEDNFESPDMIKFSAGMRDLILQQAPPHQYGILVSILNPLVASEAIIQQAAQLVADLGETERLRARRNVRMVVEKSDIHPPPRPRRPAPSVIQSGPIRVSRKQMFTDLIRAGVQFQKIDGQPNQVLLQLWKQLPNSQRFQRSPKREGVRLIERIPQNTWNLEDFIVPSKKRKPPQVARAATVEPSEEKDLGIAQLMA", "length": 529, "header": "tr|A0A8V0YH39-1|A0A8V0YH39_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0YH39-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YH39-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH39/entry#A0A8V0YH39-1", "sequence": { "sequence": "MTFLNNFMGWFGWGKASPISEVLPGHIPGFLGSPYHGIACIIEKWGPLRDAGNVQESPARLAEYFSSLNKNVLTTRERQLAASTVAWPLLMALNRLNITEGVLTDENQLLRDRVEELERQVAILRGKKPNPIIPVQKIRNISLEITGDPIQESPHELDSENESTKKSDLEAPLELDPFEIRPVVTQKTKKTQDRPAGLPPDQWPPAQSTLHVTARPYTAAELMDLVQRFRQRPRESVPAWLLRLYDMGAESVVVNGPEISKLASITTHPALRQRLYAAVQHNEENHSLIAWLMAACRVTWANKTDIPLNTGLWSSMEDLQNYIRELGMKEAIYEDNFESPDMIKFSAGMRDLILQQAPPHQYGILVSILNPLVASEAIIQQAAQLVADLGETERLRARRNVRMVVEKSDIHPPPRPRRPAPSVIQSGPIRVSRKQMFTDLIRAGVQFQKIDGQPNQVLLQLWKQLPNSQRFQRSPKREGVRLIERIPQNTWNLEDFIVPSKKRKPPQVARAATVEPSEEKDLGIAQLMA", "length": 529, "header": "tr|A0A8V0YH39-1|A0A8V0YH39_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0YH39-1" }, "locus": { "chromosome": "2", "start_pos": 123982996, "end_pos": 123981410, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030770.1", "url": "https://www.ensembl.org/id/ENSGALT00010030770.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017845.1", "url": "https://www.ensembl.org/id/ENSGALP00010017845.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YH39", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH39" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "response to virus", "id": "GO:0009615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009615", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YH39", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH39" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 140, "end_pos": 142, "annotation": "n_glycosylation_sequon" }, { "start_pos": 161, "end_pos": 163, "annotation": "n_glycosylation_sequon" }, { "start_pos": 285, "end_pos": 287, "annotation": "n_glycosylation_sequon" }, { "start_pos": 302, "end_pos": 304, "annotation": "n_glycosylation_sequon" }, { "start_pos": 97, "end_pos": 99, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 140, "end_pos": 142 }, { "start_pos": 161, "end_pos": 163 }, { "start_pos": 285, "end_pos": 287 }, { "start_pos": 302, "end_pos": 304 }, { "start_pos": 97, "end_pos": 99 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YH40-1", "uniprot_ac": "A0A8V0YH40", "uniprot_id": "A0A8V0YH40_CHICK", "mass": { "chemical_mass": 87303.0, "monoisotopic_mass": 87303.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Cadherin domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A8V0YH40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH40/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YH40", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH40#function" }, { "database": "UniProtKB", "id": "ARBA00003436", "url": "https://www.uniprot.org/uniprotkb/ARBA00003436#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YH40", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH40" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH40", "locus": {} } ], "crossref": [ { "id": "A0A8V0YH40", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YH40", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd11304", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11304", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR002126", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002126", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013164", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013164", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015919", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015919", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020894", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020894", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032455", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032455", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050174", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050174", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR24028", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24028", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24028:SF118", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24028:SF118", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00028", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00028", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08266", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08266", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16492", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16492", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YH40", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH40", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YH40-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH40-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQSYPVTWRPFLQVLCLWALLGVPRVRCEPIRYSVAEEGESGSVVADVAEDAGLAPAQLSARRARIASPAGRQHFRLERGSGRLVVAERLDREEMCGRSRTCTLAFELLLADPLQFFPIEVSVEDINDHSPVFPDERVTFKIPERGDPGTRFPVGAAQDLDIGSNDIQAYSIIPENEYFTVFIQSENEKFIELVLEKPLDREEQPEMDFTLVATDGGSPPRTGSTEIHITVLDINDNVPVFTQKVYIGHVLENAPEGSVVLRVVANDADEGVNGDISYQFSQSVVHRHSLFTINPKTGEIGIAKPLDFETEKKHKLTVQAVDGGGLSSMCNVIVEVLDVNDNAPEIVVSSFNSPLPENVEPGTVIALFAVRDQDSGINGEITCALEEQLSFALRPAFKNYYELVTVSTLDREERAQHMVVVTAADAGSPPLTSTHTFSVDISDVNDNAPVFNQTSYTMYVHENNAPALLVGAVKATDADAGPNAKVSYSVVPARGPEEEPCSCVSVNSESGGVFVLRPLDYEQLRQLEVVVSAADAGSPPLSSSVSVRLLVVDENDNAPLVLHPSAQDSSPPSSELVPAGAEAGDLVSKVVAVDADSGQNSWLSYQLLRATEPGLFAVGAQSGEVRLRRPPTERDAAKQKLVVLVRDNGRPPLSATAALSVLLVPGSWDAQLPQQSPAAGEDDGSLTTSLIIALVFVSLLFLLSAAAFVACKVCKRKELSSGPVLYGASSVQSYVADGAAAGTLPHAYCYEVSLTTGSGNSEFKFLKPVLPSLPAQHCSTGVGGAHAEEFPPVPVTMGDADFESPGMQSVAQLNGF", "length": 816, "header": "tr|A0A8V0YH40-1|A0A8V0YH40_CHICK Isoform 1 of Cadherin domain-containing protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0YH40-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YH40-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH40/entry#A0A8V0YH40-1", "sequence": { "sequence": "MQSYPVTWRPFLQVLCLWALLGVPRVRCEPIRYSVAEEGESGSVVADVAEDAGLAPAQLSARRARIASPAGRQHFRLERGSGRLVVAERLDREEMCGRSRTCTLAFELLLADPLQFFPIEVSVEDINDHSPVFPDERVTFKIPERGDPGTRFPVGAAQDLDIGSNDIQAYSIIPENEYFTVFIQSENEKFIELVLEKPLDREEQPEMDFTLVATDGGSPPRTGSTEIHITVLDINDNVPVFTQKVYIGHVLENAPEGSVVLRVVANDADEGVNGDISYQFSQSVVHRHSLFTINPKTGEIGIAKPLDFETEKKHKLTVQAVDGGGLSSMCNVIVEVLDVNDNAPEIVVSSFNSPLPENVEPGTVIALFAVRDQDSGINGEITCALEEQLSFALRPAFKNYYELVTVSTLDREERAQHMVVVTAADAGSPPLTSTHTFSVDISDVNDNAPVFNQTSYTMYVHENNAPALLVGAVKATDADAGPNAKVSYSVVPARGPEEEPCSCVSVNSESGGVFVLRPLDYEQLRQLEVVVSAADAGSPPLSSSVSVRLLVVDENDNAPLVLHPSAQDSSPPSSELVPAGAEAGDLVSKVVAVDADSGQNSWLSYQLLRATEPGLFAVGAQSGEVRLRRPPTERDAAKQKLVVLVRDNGRPPLSATAALSVLLVPGSWDAQLPQQSPAAGEDDGSLTTSLIIALVFVSLLFLLSAAAFVACKVCKRKELSSGPVLYGASSVQSYVADGAAAGTLPHAYCYEVSLTTGSGNSEFKFLKPVLPSLPAQHCSTGVGGAHAEEFPPVPVTMGDADFESPGMQSVAQLNGF", "length": 816, "header": "tr|A0A8V0YH40-1|A0A8V0YH40_CHICK Isoform 1 of Cadherin domain-containing protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0YH40-1" }, "locus": { "chromosome": "13", "start_pos": 1332224, "end_pos": 1329115, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026919.1", "url": "https://www.ensembl.org/id/ENSGALT00010026919.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015332.1", "url": "https://www.ensembl.org/id/ENSGALP00010015332.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YH40", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH40" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YH40", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH40" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "homophilic cell adhesion via plasma membrane adhesion molecules", "id": "GO:0007156", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007156", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YH40", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH40" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 452, "end_pos": 454, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YH40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH40" }, { "id": "PS50268", "database": "PROSITE", "url": 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NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052571.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 1, 2022 this sequence version replaced XP_004949353.2. 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"database": "Ensembl Peptide", "id": "ENSGALP00010015353.1", "url": "https://www.ensembl.org/id/ENSGALP00010015353.1" } ] } }, { "isoform_ac": "A0A8V0YH59-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH59/entry#A0A8V0YH59-1", "sequence": { "sequence": "MSLPKIQIEEALDRTDAGTGSAVPPDDHLRSLKALTEKLRLETRRPSYLEWKAKLEEQAWKSPQPVGDEEGNEAKKGAEDTVPLRKVQLHLNGSPAQDKVTLTSGKIGDFESIDEALTWLRKELVTHLSARFCHLHMKIWPWYIGLNMPTELQPALSAGTCWESGPEKLIYSDMQIPALVFVLRGSVNAPAGPAAGQAADAPPQRHQQAEDRADLPPPPAHAQRRHV", "length": 227, "header": "tr|A0A8V0YH59-1|A0A8V0YH59_CHICK Isoform 1 of Family with sequence similarity 167 member A OS=Gallus gallus OX=9031 GN=FAM167A PE=4 SV=1 CANONICAL=A0A8V0YH59-1" }, "locus": { "chromosome": "3", "start_pos": 107022791, "end_pos": 107012892, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026962.1", "url": "https://www.ensembl.org/id/ENSGALT00010026962.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015352.1", "url": 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"Fam167a", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSVPRIQVDEVGENDRPAGAAAPPDDHLLSLKALTEKLRLETRRPSYLEWQARLEEQTWPFPRSAAQQEASLEEGACGGGEPSIPLRESRELLPPARSASQGDGPLTTGKLEGFQSIDEAITWLRKELAEMRLQDQQLARQLMRLRGDINKLKIEQTCRLHRRMLNDAAYELEERDELSDLFCDSPLASSFSLSTPLKLIGVTKMNINSRRFSLC", "length": 215 }, "evidence": [ { "id": "A0A8V0YH59", "url": "https://omabrowser.org/oma/group/A0A8V0YH59/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "D3ZQX1-1", "protein_name": "Family with sequence similarity 167, member A", "gene_name": "Fam167a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSVPRIQVEEVGEKDRPAGAAIPPDDHLLSLKALTEKLRLETRRPSYLEWQAKLEEQTWPFPRPAAQQEASLEQGACGGGEPLMSLREPRELLPPARSASGGDRPLATDKLEGFRSIDEAIAWLRKELAEMRLQDQQLARQLMRLRGDINKMKIEQTCRLHRRMLNDAAFELEERDELSDLFCDSPLAASFSLSTPLKLIGVTKMNINSRRFSLC", "length": 215 }, "evidence": [ { "id": "A0A8V0YH59", "url": 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"MDASSIPQINIEDFDGLEVAPDDHLRNLKALTEKLRLETRRPSYLEWKERVEAQNTKGLAVSDGSTELEKDAGLKPRATPQRTIEDSQMTAGNGLISRSLGGFDNIDEALVWLRKELMEMRIQDQQLARQLMRLRGDINKLKVEQTCHLHRRMLNDATFGLEERDELSDLLCDGPVTPGFGLSSPLRLIGVTKMNINSRRFSLC", "length": 204 }, "evidence": [ { "id": "A0A8V0YH59", "url": "https://omabrowser.org/oma/group/A0A8V0YH59/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q6P1G6-1", "protein_name": "Protein FAM167A", "gene_name": "Fam167a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSVPQIQVEEVSEKDRPAGAAVPPDDHLLSLKALTEKLRLETRRPSYLEWQARLEEQTWPFPRPAAQQEASLEQGACGGGEPLMPLKEPRDLLPPSASAGRGDRPLTTGKLEGFQSIDEAIAWLRKELAEMRLQDQQLARQLMRLRGDINKLKIEQTCRLHRRMLNDAAFELEERDELSDLFCDSPLASSFSLSMPLKLIGVTKMNINSRRFSLC", "length": 215 }, "evidence": [ { "id": "A0A8V0YH59", "url": "https://omabrowser.org/oma/group/A0A8V0YH59/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": 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"annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052533.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040551850", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040551850" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YH92", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH92" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "VPS13B", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH92", "locus": { "chromosome": "2", "start_pos": 127873893, "end_pos": 127462314, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010011312", "url": "https://www.ensembl.org/id/ENSGALG00010011312" } ] } } ], "crossref": [ { "id": "420242", "url": "https://www.ncbi.nlm.nih.gov/gene/420242", "database": "GeneID", 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"OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YH92", "url": "https://www.orthodb.org/?gene=A0A8V0YH92", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12517", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12517", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12517:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12517:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF12624", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12624", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25033", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25033", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25036", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25036", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_040551850", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040551850", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YCK3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCK3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YCK3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCK3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YCL0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCL0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YCL0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCL0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YH92", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH92", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YH92-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH92-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLESYVTPILMSYVNRYIKNLKPSDLQLSLWGGDVVLSKLELKLDVLEQELKLPFTFLSGHIHELRIHVPWTKLGSEPVVITINTMECILKLKDGAQQEDHESCGSSSTNRSTTESMKSAVKPRRVQQSASPDPDLPPGYVQSLIRRVVNNVNIVINNLILKYVEDDIVLSVNITSAECYTVDEFWDRAFMDISATDLVLRKMINFSDCTVCLDKRNASGKIEFYQEPLLYKCSFKTRLHFTYDNLNSKMPSIIKIHTFVESLKLSISDQQLPMFIRIMQLGIALYYGEIGNFKDGESEDSICHTKDMLGNITGAEDETGSVMQYPTQYVTQDPYLHQDDDQQQGWVSWAWSFVPAIVSYDDEENESSGTDDGTTLRQQKSQSLKDPIISIGFYCSKATVTFKLTEMQAESSYYSPQKVKSKEVLCWEQEGTTIEVLMKGELFFDCQVGFVGCQAMCLKGIMGIKDFEENVNRNDEEAYFFSCGENTSAKGKTYLTNSLFDYRSPENNSIRAEFILDAAHHKETYTEIAGMQRFGAFYMDYLYTMESTSGKVSGNQQDPSSVKNEEFGNVQEMSTKSIIVGPLNLRLDSSAVHRIMKMIVCALEHEYEPYCRTKPDLVDGNRTIPSSEEVASLEEYIPTRLTTFTILKCTIIIPVAEFNLLDHLMPVIMGEKNFSGLLNATSFQPLRPLPSVRILVDKINLEHSVPMYAEQLVNTVSSLSQPSDNLLHYSYSHCYLKVFGFQAALTSLDSRGLYSFPVPVIPSFSTALYGKLIKFPKYWTKRAHVPLTECIFELPNLTVQATRAQTLLLQTIYQSWCHPVGNVSSVVVNEALLNEVFQSSGVKSKNPLPTLEGSVQNVELKYCSTSLVKCASGTMGSIKICAKAPGDGGKEKLIPIIQGPSDTRDLHSSKWLNESRKPESLLAPDLVAFTIQIPQYMDYCHNSGAVLLSSIQGLAINVDPVLYTWLIYQPQKRASRHIQQQSVGAVPLGVSVARKKEDEASVGSAPLARQQSNQASEYASSPVKTKTITESRPLSLPVKTMLNSSEGCRSPEERMKEFIGIVWNAVKRLTLQLEVQSCCVFLPNDSLPSPSTIVSGDIPGTVRSWYHGQASMPGTLVVCLPQIKIMSAGHKHMEPLQEIPFVVLRPILEEGDAFPWTISLHHFSMYTLLGQQMTLNLVEPMGCTSTLAVTSQKLLASGPESRHSFVVCLHVDLESLEIKCSNPQVQLLYELAEITSKVWNKIQRRGILYQSSVYTETMTGPAPPSSPVKSSVGTVPPDTSTYSPSADVGTTTEGDSLQGGDDSPFSDSITLEQTTSNIGVSSGRVSLWMQWMLPKITIKLFAPDPRNNGTEVCVVSELEDLSASVDMQDVYTKIKCKIESFNVDHYRNSLGEDSWSLGQYGGVFLSCTDKLNRRTLLVRPISKQDPFSNFSGFFPSATAKLLDGSHQQHGFLSLTYTKAVTKNVRHKLISRNERRTFHKLSEGHTDGSPHFLHEILLSAQAFDVVLCFPLLNAIASIFQARLPRSQKEKRKTPGQPMRTHTLTSRNLPLIYINTGVIRVFFPKNEEDHHNVEANPAIKEDTLVLKIGSVSMAPQADNPLSRAVLRKDIYQRALNLGILRDPGSEVEDRQYQIDLQSINIGTAHWNQLKPEKENGKGGILPESERNSQNPALEWNMASSIRRHQERRAILTPILTDFTVRVTAAPAIIFTKIDAPENLHPEEILVCGHSLEVNVTTNLDFFLNVAQVQLLQQLVEANMIGLEPSSTINEVSKQEQKKMDVSDGGMVETSSRYSGAQDSGIGSDSVKIRIVQIEQHSGTSQHRIAQPSRQSSIVKNLNFIPFDIFVTASRISLMTYSCTALPKLKSPQDQKDGEKISKSSLNLPEAGSGSSHDTKRPSQPSISSVTADDLLNSNVPLSSGRKTGLLSLETLHASTRSSARQALGITIVRQPGRRGTGDIELQPFLYLVVSQPSVLLSCHHRKQKIEVSVFDAGLKGVASDYKCTDPGKTLPEALDYCKIWLQTVAGEVDAKSGIPPSLITVQIKDFLNGPADVNIDVSKPLKANLSFVKLDQLKEFLKKIMTTNDNKPGKETAPSTGTHPDEAVASGAKHSSTKGSPPAVHTSAAQKVSVQENLWQALSCFQKISIHTVQMVVSMETVPHPSKPCLLASLSNLSGSLNIKGGLKTAGIHGSCLVLDIKDFLLKTCLKERTRSLIGPFCCSVTVEAKWCKHSGDPGPEQSIPKMYIDLKGGLLQVFWGQEHLNCLVLLQELVWEYLTKTGSAETFVSERRYRASSSTERNQASKTEHSSDDLRTGLFQYIQDAEAQKLPGAYEVVFYNETEDSPGMMLWRYPEPRVLTLVRINPVPFNTTEDPDISTADLGDVLQIPCSLEYWDELQKSFVAFREFSLSESKVCELQLPNVSLVNDQKELIASDLWRIVLNSNQNVVDDQSSESESGSQSACDQLVTPTALAACTRVDSCFTPWFVPSVSVLVQFSFLEVHLCHHLDQLGTAPPKFLQPFLSDKNMPSELEYMIISFDEPHVYLRQWSDESVFQELQFSTQADCKLLECRNVTMQSVVKPFKIWGQIAISGGTGRRLLDCTIMVDPILILFGQYAIHSLNTAIQAWQQNQCPEAEELVFSHFVICNDTQETLRFGQVDTDENILLASLHSHQYSWRSHKSPQLLHICIEGWGNWRWSEPFSVDNAGTFIRTIQYKGRTASLIIKVQQLSGVQKQILICGRQTVCSYLSESIELKVVQHYISQDGQAVVKEHINCLAAKQKLPSYVLEDDELTELSVKATGDEDWSQDVCLSSEHTEHSTVIQVPSSKSLITYVWCTILTLEPSSHVQQRIIVFSPLFIVRSHLPDPIIIHLEKRSLGLNETQVVPGKGQEKALQNIEPDLTHHLTFQAREEDDPSECAVPISTTLIKQIATKSHPGGNVSQILSEFYGTANPRQPAWPYNKKDSDSSEQLSQWDSPMRVKLSVWKPCVKTLLIELLPWALLINQSKWDLWLFEGEKIVLQVPTGKVMIPPNFEEAFQVGIYWANTNTVHKSVAIKLVHDVTSPKWKDAENGEVVTLDEEGFVEAEIKLGAFPGHQKLCQFCISSMVRQGIQILQIEDKTTIINDTSYQIYYRPQLCISKPYSGEEDFYSADSTVFSVGPARTKNTETLTSVPCWDLLADSSPITSGTPPTQKRMLLSFSPGGSSEFWSLPAVIKQEFPRQSVAVPIGACTESGFYTRAITLTYQEHLGVTYLTLTEDPSPRIIIHNRCSISLLVKENFKDTPKFEVYCRKIPAECSIHHELYHQISSYPDCKTRDLLPSILLKVMSSDDLVNEWSDIVDINNQGTQVVFLTGFGYVYVDIVHQCGTIIITLAPEGRAGPVEINLNRSQEQSLFLKVFISQLSLAVFDDITNHKVSSELLRLTADNVFLHMAPTTSYLRPLSRELQQDTGEGLPPFYSLQVYCEDLQLDNQLYSKSNFHFAVLLCQGEKNETMQWSRANNLIVSNKDLENYKENCFIKLCIAFSEEENFTFHVNDLSFELKPARLYVEDTFVYYIKTLFDTYLPENKGAWQSVNSSDTTQILPKQVREHARALVKPVKLRKLTIQPVNLLVSIHASLKLYIASDHTPLSFSVFERGPIFTTARQLVHALAMHYAAGALFRAGWVVGSLEILGSPASLVRSIGNGIADFFRLPYEGLTRGPGAFVSGVSRGTTSFVKHISKGTLTSITNLATSLARNMDRLSLDEEHYNRQEEWRRQLPENLGEGLRQGLSRLGISLLGAIAGIVDQPMQNFQRVSEGQASAGHKAKGVISGVGKGIMGVFTKPIGGAAELVSQTGYGILHGAGLSQLPKQRSHPNDQQVEQAPNSHVKYVWKMLQSLGKPEVHMALDVMIVSGSGQQHDGCLLLTSEVLFVVSISEDTQQQAFPVTEIDCLEDDQQKDLLKVQLKQQRVPCDLEADGVRERLSEQQYNRLVEYVTKTSYHLAPSTTTVPAPQAVAAEHLPTVTKTYNYVVDPNFAQVFISKFIMVKNKALRKGFY", "length": 4031, "header": "tr|A0A8V0YH92-1|A0A8V0YH92_CHICK Isoform 1 of Vacuolar protein sorting 13 homolog B OS=Gallus gallus OX=9031 GN=VPS13B PE=3 SV=1 CANONICAL=A0A8V0YH92-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YCK3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH92/entry#A0A8V0YCK3-1", "sequence": { "sequence": "MLESYVTPILMSYVNRYIKNLKPSDLQLSLWGGDVVLSKLELKLDVLEQELKLPFTFLSGHIHELRIHVPWTKLGSEPVVITINTMECILKLKDGAQQEDHESCGSSSTNRSTTESMKSAVKPRRVQQSASPDPDLPPGYVQSLIRRVVNNVNIVINNLILKYVEDDIVLSVNITSAECYTVDEFWDRAFMDISATDLVLRKMINFSDCTVCLDKRNASGKIEFYQEPLLYKCSFKTRLHFTYDNLNSKMPSIIKIHTFVESLKLSISDQQLPMFIRIMQLGIALYYGEIGNFKDGESEDSICHTKDMLGNITGAEDETGSVMQYPTQYVTQDPYLHQDDDQQQGWVSWAWSFVPAIVSYDDEENESSGTDDGTTLRQQKSQSLKDPIISIGFYCSKATVTFKLTEMQAESSYYSPQKVKSKEVLCWEQEGTTIEVLMKGELFFDCQVGFVGCQAMCLKGIMGIKDFEENVNRNDEEAYFFSCGENTSAKGKTYLTNSLFDYRSPENNSIRAEFILDAAHHKETYTEIAGMQRFGAFYMDYLYTMESTSGKVSGNQQDPSSVKNEEFGNVQEMSTKSIIVGPLNLRLDSSAVHRIMKMIVCALEHEYEPYCRTKPDLVDGNRTIPSSEEVASLEEYIPTRLTTFTILKCTIIIPVAEFNLLDHLMPVIMGEKNFSGLLNATSFQPLRPLPSVRILVDKINLEHSVPMYAEQLVNTVSSLSQPSDNLLHYSYSHCYLKVFGFQAALTSLDSRGLYSFPVPVIPSFSTALYGKLIKFPKYWTKRAHVPLTECIFELPNLTVQATRAQTLLLQTIYQSWCHPVGNVSSVVVNEALLNEVFQSSGVKSKNPLPTLEGSVQNVELKYCSTSLVKCASGTMGSIKICAKAPGDGGKEKLIPIIQGPSDTRDLHSSKWLNESRKPESLLAPDLVAFTIQIPQYMDYCHNSGAVLLSSIQGLAINVDPVLYTWLIYQPQKRASRHIQQQSVGAVPLGVSVARKKEDEASVGSAPLARQQSNQASEYASSPVKTKTITESRPLSLPVKTMLNSSEGCRSPEERMKEFIGIVWNAVKRLTLQLEVQSCCVFLPNDSLPSPSTIVSGDIPGTVRSWYHGQASMPGTLVVCLPQIKIMSAGHKHMEPLQEIPFVVLRPILEEGDAFPWTISLHHFSMYTLLGQQMTLNLVEPMGCTSTLAVTSQKLLASGPESRHSFVVCLHVDLESLEIKCSNPQVQLLYELAEITSKVWNKIQRRGILYQSSVYTETMTGPAPPSSPVKSSVGTVPPDTSTYSPSADVGTTTEGDSLQGGDDSPFSDSITLEQTTSNIGVSSGRVSLWMQWMLPKITIKLFAPDPRNNGTEVCVVSELEDLSASVDMQDVYTKIKCKIESFNVDHYRNRPGEGWQSAHFERIFLQCREKTLATAKLLDGSHQQHGFLSLTYTKAVTKNVRHKLISRNERRTFHKLSEGHTDGSPHFLHEILLSAQAFDVVLCFPLLNAIASIFQARLPRSQKEKRKTPGQPMRTHTLTSRNLPLIYINTGVIRVFFPKNEEDHHNVEANPAIKEDTLVLKIGSVSMAPQADNPLSRAVLRKDIYQRALNLGILRDPGSEVEDRQYQIDLQSINIGTAHWNQLKPEKENGKGGILPESERNSQNPALEWNMASSIRRHQERRAILTPILTDFTVRVTAAPAIIFTKIDAPENLHPEEILVCGHSLEVNVTTNLDFFLNVAQVQLLQQLVEANMIGLEPSSTINEVSKQEQKKMDVSDGGMVETSSRYSGAQDSGIGSDSVKIRIVQIEQHSGTSQHRIAQPSRQSSIVKNLNFIPFDIFVTASRISLMTYSCTALPKLKSPQDQKDGEKISKSSLNLPEAGSGSSHDTKRPSQPSISSVTADDLLNSNVPLSSGRKTGLLSLETLHASTRSSARQALGITIVRQPGRRGTGDIELQPFLYLVVSQPSVLLSCHHRKQKIEVSVFDAGLKGVASDYKCTDPGKTLPEALDYCKIWLQTVAGEVDAKSGIPPSLITVQIKDFLNGPADVNIDVSKPLKANLSFVKLDQLKEFLKKIMTTNDNKPGKETAPSTGTHPDEAVASGAKHSSTKGSPPAVHTSAAQKVSVQENLWQALSCFQKISIHTVQMVVSMETVPHPSKPCLLASLSNLSGSLNIKGGLKTAGIHGSCLVLDIKDFLLKTCLKERTRSLIGPFCCSVTVEAKWCKHSGDPGPEQSIPKMYIDLKGGLLQVFWGQEHLNCLVLLQELVWEYLTKTGSAETFVSERRYRASSSTERNQASKTEHSSDDLRTGLFQYIQDAEAQKLPGAYEVVFYNETEDSPGMMLWRYPEPRVLTLVRINPVPFNTTEDPDISTADLGDVLQIPCSLEYWDELQKSFVAFREFSLSESKVCELQLPNVSLVNDQKELIASDLWRIVLNSNQNVVDDQSSESESGSQSACDQLVTPTALAACTRVDSCFTPWFVPSVSVLVQFSFLEVHLCHHLDQLGTAPPKFLQPFLSDKNMPSELEYMIISFDEPHVYLRQWSDESVFQELQFSTQADCKLLECRNVTMQSVVKPFKIWGQIAISGGTGRRLLDCTIMVDPILILFGQYAIHSLNTAIQAWQQNQCPEAEELVFSHFVICNDTQETLRFGQVDTDENILLASLHSHQYSWRSHKSPQLLHICIEGWGNWRWSEPFSVDNAGTFIRTIQYKGRTASLIIKVQQLSGVQKQILICGRQTVCSYLSESIELKVVQHYISQDGQAVVKEHINCLAAKQKLPSYVLEDDELTELSVKATGDEDWSQDVCLSSEHTEHSTVIQVPSSKSLITYVWCTILTLEPSSHVQQRIIVFSPLFIVRSHLPDPIIIHLEKRSLGLNETQVVPGKGQEKALQNIEPDLTHHLTFQAREEDDPSECAVPISTTLIKQIATKSHPGGNVSQILSEFYGTANPRQPAWPYNKKDSDSSEQLSQWDSPMRVKLSVWKPCVKTLLIELLPWALLINQSKWDLWLFEGEKIVLQVPTGKVMIPPNFEEAFQVGIYWANTNTVHKSVAIKLVHDVTSPKWKDAENGEVVTLDEEGFVEAEIKLGAFPGHQKLCQFCISSMVRQGIQILQIEDKTTIINDTSYQIYYRPQLCISKPYSGEEDFYSADSTVFSVGPARTKNTETLTSVPCWDLLADSSPITSGTPPTQKRMLLSFSPGGSSEFWSLPAVIKQEFPRQSVAVPIGACTESGFYTRAITLTYQEHLGVTYLTLTEDPSPRIIIHNRCSISLLVKENFKDTPKFEVYCRKIPAECSIHHELYHQISSYPDCKTRDLLPSILLKVMSSDDLVNEWSDIVDINNQGTQVVFLTGFGYVYVDIVHQCGTIIITLAPEGRAGPVEINLNRSQEQSLFLKVFISQLSLAVFDDITNHKVSSELLRLTADNVFLHMAPTTSYLRPLSRELQQDTGEGLPPFYSLQVYCEDLQLDNQLYSKSNFHFAVLLCQGEKNETMQWSRANNLIVSNKDLENYKENCFIKLCIAFSEEENFTFHVNDLSFELKPARLYVEDTFVYYIKTLFDTYLPENKGAWQSVNSSDTTQILPKQVREHARALVKPVKLRKLTIQPVNLLVSIHASLKLYIASDHTPLSFSVFERGPIFTTARQLVHALAMHYAAGALFRAGWVVGSLEILGSPASLVRSIGNGIADFFRLPYEGLTRGPGAFVSGVSRGTTSFVKHISKGTLTSITNLATSLARNMDRLSLDEEHYNRQEEWRRQLPENLGEGLRQGLSRLGISLLGAIAGIVDQPMQNFQRVSEGQASAGHKAKGVISGVGKGIMGVFTKPIGGAAELVSQTGYGILHGAGLSQLPKQRSHPNDQQVEQAPNSHVKYVWKMLQSLGKPEVHMALDVMIVSGSGQQHDGCLLLTSEVLFVVSISEDTQQQAFPVTEIDCLEDDQQKDLLKVQLKQQRVPCDLEADGVRERLSEQQYNRLVEYVTKTSYHLAPSTTTVPAPQAVAAEHLPTVTKTYNYVVDPNFAQVFISKFIMVKNKALRKGFY", "length": 4006, "header": "tr|A0A8V0YCK3-1|A0A8V0YCK3_CHICK Computationally mapped isoform of Vacuolar protein sorting 13 homolog B OS=Gallus gallus OX=9031 GN=VPS13B PE=3 SV=1 CANONICAL=A0A8V0YH92-1" }, "locus": { "chromosome": "2", "start_pos": 127872226, "end_pos": 127462992, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027049.1", "url": "https://www.ensembl.org/id/ENSGALT00010027049.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015394.1", "url": "https://www.ensembl.org/id/ENSGALP00010015394.1" } ] } }, { "isoform_ac": "A0A8V0YCL0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH92/entry#A0A8V0YCL0-1", "sequence": { "sequence": "MLESYVTPILMSYVNRYIKNLKPSDLQLSLWGGDVVLSKLELKLDVLEQELKLPFTFLSGHIHELRIHVPWTKLGSEPVVITINTMECILKLKDGAQQEDHESCGSSSTNRSTTESMKSAVKPRRVQQSASPDPDLPPGYVQSLIRRVVNNVNIVINNLILKYVEDDIVLSVNITSAECYTVDEFWDRAFMDISATDLVLRKMINFSDCTVCLDKRNASGKIEFYQEPLLYKCSFKTRLHFTYDNLNSKMPSIIKIHTFVESLKLSISDQQLPMFIRIMQLGIALYYGEIGNFKDGESEDSICHTKDMLGNITGAEDETGSVMQYPTQYVTQDPYLHQDDDQQQGWVSWAWSFVPAIVSYDDEENESSGTDDGTTLRQQKSQSLKDPIISIGFYCSKATVTFKLTEMQAESSYYSPQKVKSKEVLCWEQEGTTIEVLMKGELFFDCQVGFVGCQAMCLKGIMGIKDFEENVNRNDEEAYFFSCGENTSAKGKTYLTNSLFDYRSPENNSIRAEFILDAAHHKETYTEIAGMQRFGAFYMDYLYTMESTSGKVSGNQQDPSSVKNEEFGNVQEMSTKSIIVGPLNLRLDSSAVHRIMKMIVCALEHEYEPYCRTKPDLVDGNRTIPSSEEVASLEEYIPTRLTTFTILKCTIIIPVAEFNLLDHLMPVIMGEKNFSGLLNATSFQPLRPLPSVRILVDKINLEHSVPMYAEQLVNTVSSLSQPSDNLLHYSYSHCYLKVFGFQAALTSLDSRGLYSFPVPVIPSFSTALYGKLIKFPKYWTKRAHVPLTECIFELPNLTVQATRAQTLLLQTIYQSWCHPVGNVSSVVVNEALLNEVFQSSGAVLLSSIQGLAINVDPVLYTWLIYQPQKRASRHIQQQSVGAVPLGVSVARKKEDEASVGSAPLARQQSNQASEYASSPVKTKTITESRPLSLPVKTMLNSSEGCRSPEERMKEFIGIVWNAVKRLTLQLEVQSCCVFLPNDSLPSPSTIVSGDIPGTVRSWYHGQASMPGTLVVCLPQIKIMSAGHKHMEPLQEIPFVVLRPILEEGDAFPWTISLHHFSMYTLLGQQMTLNLVEPMGCTSTLAVTSQKLLASGPESRHSFVVCLHVDLESLEIKCSNPQVQLLYELAEITSKVWNKIQRRGILYQSSVYTETMTGPAPPSSPVKSSVGTVPPDTSTYSPSADVGTTTEGDSLQGGDDSPFSDSITLEQTTSNIGVSSGRVSLWMQWMLPKITIKLFAPDPRNNGTEVCVVSELEDLSASVDMQDVYTKIKCKIESFNVDHYRNSLGEDSWSLGQYGGVFLSCTDKLNRRTLLVRPISKQDPFSNFSGFFPSATAKLLDGSHQQHGFLSLTYTKAVTKNVRHKLISRNERRTFHKLSEGHTDGSPHFLHEILLSAQAFDVVLCFPLLNAIASIFQARLPRSQKEKRKTPGQPMRTHTLTSRNLPLIYINTGVIRVFFPKNEEDHHNVEANPAIKEDTLVLKIGSVSMAPQADNPLSRAVLRKDIYQRALNLGILRDPGSEVEDRQYQIDLQSINIGTAHWNQLKPEKENGKGGILPESERNSQNPALEWNMASSIRRHQERRAILTPILTDFTVRVTAAPAIIFTKIDAPENLHPEEILVCGHSLEVNVTTNLDFFLNVAQVQLLQQLVEANMIGLEPSSTINEVSKQEQKKMDVSDGGMVETSSRYSGAQDSGIGSDSVKIRIVQIEQHSGTSQHRIAQPSRQSSIVKNLNFIPFDIFVTASRISLMTYSCTALPKLKSPQDQKDGEKISKSSLNLPEAGSGSSHDTKRPSQPSISSVTADDLLNSNVPLSSGRKTGLLSLETLHASTRSSARQALGITIVRQPGRRGTGDIELQPFLYLVVSQPSVLLSCHHRKQKIEVSVFDAGLKGVASDYKCTDPGKTLPEALDYCKIWLQTVAGEVDAKSGIPPSLITVQIKDFLNGPADVNIDVSKPLKANLSFVKLDQLKEFLKKIMTTNDNKPGKETAPSTGTHPDEAVASGAKHSSTKGSPPAVHTSAAQKVSVQENLWQALSCFQKISIHTVQMVVSMETVPHPSKPCLLASLSNLSGSLNIKGGLKTAGIHGSCLVLDIKDFLLKTCLKERTRSLIGPFCCSVTVEAKWCKHSGDPGPEQSIPKMYIDLKGGLLQVFWGQEHLNCLVLLQELVWEYLTKTGSAETFVSERRYRASSSTERNQASKTEHSSDDLRTGLFQYIQDAEAQKLPGAYEVVFYNETEDSPGMMLWRYPEPRVLTLVRINPVPFNTTEDPDISTADLGDVLQIPCSLEYWDELQKSFVAFREFSLSESKVCELQLPNVSLVNDQKELIASDLWRIVLNSNQNVVDDQSSESESGSQSACDQLVTPTALAACTRVDSCFTPWFVPSVSVLVQFSFLEVHLCHHLDQLGTAPPKFLQPFLSDKNMPSELEYMIISFDEPHVYLRQWSDESVFQELQFSTQADCKLLECRNVTMQSVVKPFKIWGQIAISGGTGRRLLDCTIMVDPILILFGQYAIHSLNTAIQAWQQNQCPEAEELVFSHFVICNDTQETLRFGQVDTDENILLASLHSHQYSWRSHKSPQLLHICIEGWGNWRWSEPFSVDNAGTFIRTIQYKGRTASLIIKVQQLSGVQKQILICGRQTVCSYLSESIELKVVQHYISQDGQAVVKEHINCLAAKQKLPSYVLEDDELTELSVKATGDEDWSQDVCLSSEHTEHSTVIQVPSSKSLITYVWCTILTLEPSSHVQQRIIVFSPLFIVRSHLPDPIIIHLEKRSLGLNETQVVPGKGQEKALQNIEPDLTHHLTFQAREEDDPSECAVPISTTLIKQIATKSHPGGNVSQILSEFYGTANPRQPAWPYNKKDSDSSEQLSQWDSPMRVKLSVWKPCVKTLLIELLPWALLINQSKWDLWLFEGEKIVLQVPTGKVMIPPNFEEAFQVGIYWANTNTVHKSVAIKLVHDVTSPKWKDAENGEVVTLDEEGFVEAEIKLGAFPGHQKLCQFCISSMVRQGIQILQIEDKTTIINDTSYQIYYRPQLCISKPYSGEEDFYSADSTVFSVGPARTKNTETLTSVPCWDLLADSSPITSGTPPTQKRMLLSFSPGGSSEFWSLPAVIKQEFPRQSVAVPIGACTESGFYTRAITLTYQEHLGVTYLTLTEDPSPRIIIHNRCSISLLVKENFKDTPKFEVYCRKIPAECSIHHELYHQISSYPDCKTRDLLPSILLKVMSSDDLVNEWSDIVDINNQGTQVVFLTGFGYVYVDIVHQCGTIIITLAPEGRAGPVEINLNRSQEQSLFLKVFISQLSLAVFDDITNHKVSSELLRLTADNVFLHMAPTTSYLRPLSRELQQDTGEGLPPFYSLQVYCEDLQLDNQLYSKSNFHFAVLLCQGEKNETMQWSRANNLIVSNKDLENYKENCFIKLCIAFSEEENFTFHVNDLSFELKPARLYVEDTFVYYIKTLFDTYLPENKGAWQSVNSSDTTQILPKQVREHARALVKPVKLRKLTIQPVNLLVSIHASLKLYIASDHTPLSFSVFERGPIFTTARQLVHALAMHYAAGALFRAGWVVGSLEILGSPASLVRSIGNGIADFFRLPYEGLTRGPGAFVSGVSRGTTSFVKHISKGTLTSITNLATSLARNMDRLSLDEEHYNRQEEWRRQLPENLGEGLRQGLSRLGISLLGAIAGIVDQPMQNFQRVSEGQASAGHKAKGVISGVGKGIMGVFTKPIGGAAELVSQTGYGILHGAGLSQLPKQRSHPNDQQVEQAPNSHVKYVWKMLQSLGKPEVHMALDVMIVSGSGQQHDGCLLLTSEVLFVVSISEDTQQQAFPVTEIDCLEDDQQKDLLKVQLKQQRVPCDLEADGVRERLSEQQYNRLVEYVTKTSYHLAPSTTTVPAPQAVAAEHLPTVTKTYNYVVDPNFAQVFISKFIMVKNKALRKGFY", "length": 3928, "header": "tr|A0A8V0YCL0-1|A0A8V0YCL0_CHICK Computationally mapped isoform of Vacuolar protein sorting 13 homolog B OS=Gallus gallus OX=9031 GN=VPS13B PE=3 SV=1 CANONICAL=A0A8V0YH92-1" }, "locus": { "chromosome": "2", "start_pos": 127872226, "end_pos": 127462992, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027063.1", "url": "https://www.ensembl.org/id/ENSGALT00010027063.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015399.1", "url": "https://www.ensembl.org/id/ENSGALP00010015399.1" } ] } }, { "isoform_ac": "A0A8V0YH92-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH92/entry#A0A8V0YH92-1", "sequence": { "sequence": "MLESYVTPILMSYVNRYIKNLKPSDLQLSLWGGDVVLSKLELKLDVLEQELKLPFTFLSGHIHELRIHVPWTKLGSEPVVITINTMECILKLKDGAQQEDHESCGSSSTNRSTTESMKSAVKPRRVQQSASPDPDLPPGYVQSLIRRVVNNVNIVINNLILKYVEDDIVLSVNITSAECYTVDEFWDRAFMDISATDLVLRKMINFSDCTVCLDKRNASGKIEFYQEPLLYKCSFKTRLHFTYDNLNSKMPSIIKIHTFVESLKLSISDQQLPMFIRIMQLGIALYYGEIGNFKDGESEDSICHTKDMLGNITGAEDETGSVMQYPTQYVTQDPYLHQDDDQQQGWVSWAWSFVPAIVSYDDEENESSGTDDGTTLRQQKSQSLKDPIISIGFYCSKATVTFKLTEMQAESSYYSPQKVKSKEVLCWEQEGTTIEVLMKGELFFDCQVGFVGCQAMCLKGIMGIKDFEENVNRNDEEAYFFSCGENTSAKGKTYLTNSLFDYRSPENNSIRAEFILDAAHHKETYTEIAGMQRFGAFYMDYLYTMESTSGKVSGNQQDPSSVKNEEFGNVQEMSTKSIIVGPLNLRLDSSAVHRIMKMIVCALEHEYEPYCRTKPDLVDGNRTIPSSEEVASLEEYIPTRLTTFTILKCTIIIPVAEFNLLDHLMPVIMGEKNFSGLLNATSFQPLRPLPSVRILVDKINLEHSVPMYAEQLVNTVSSLSQPSDNLLHYSYSHCYLKVFGFQAALTSLDSRGLYSFPVPVIPSFSTALYGKLIKFPKYWTKRAHVPLTECIFELPNLTVQATRAQTLLLQTIYQSWCHPVGNVSSVVVNEALLNEVFQSSGVKSKNPLPTLEGSVQNVELKYCSTSLVKCASGTMGSIKICAKAPGDGGKEKLIPIIQGPSDTRDLHSSKWLNESRKPESLLAPDLVAFTIQIPQYMDYCHNSGAVLLSSIQGLAINVDPVLYTWLIYQPQKRASRHIQQQSVGAVPLGVSVARKKEDEASVGSAPLARQQSNQASEYASSPVKTKTITESRPLSLPVKTMLNSSEGCRSPEERMKEFIGIVWNAVKRLTLQLEVQSCCVFLPNDSLPSPSTIVSGDIPGTVRSWYHGQASMPGTLVVCLPQIKIMSAGHKHMEPLQEIPFVVLRPILEEGDAFPWTISLHHFSMYTLLGQQMTLNLVEPMGCTSTLAVTSQKLLASGPESRHSFVVCLHVDLESLEIKCSNPQVQLLYELAEITSKVWNKIQRRGILYQSSVYTETMTGPAPPSSPVKSSVGTVPPDTSTYSPSADVGTTTEGDSLQGGDDSPFSDSITLEQTTSNIGVSSGRVSLWMQWMLPKITIKLFAPDPRNNGTEVCVVSELEDLSASVDMQDVYTKIKCKIESFNVDHYRNSLGEDSWSLGQYGGVFLSCTDKLNRRTLLVRPISKQDPFSNFSGFFPSATAKLLDGSHQQHGFLSLTYTKAVTKNVRHKLISRNERRTFHKLSEGHTDGSPHFLHEILLSAQAFDVVLCFPLLNAIASIFQARLPRSQKEKRKTPGQPMRTHTLTSRNLPLIYINTGVIRVFFPKNEEDHHNVEANPAIKEDTLVLKIGSVSMAPQADNPLSRAVLRKDIYQRALNLGILRDPGSEVEDRQYQIDLQSINIGTAHWNQLKPEKENGKGGILPESERNSQNPALEWNMASSIRRHQERRAILTPILTDFTVRVTAAPAIIFTKIDAPENLHPEEILVCGHSLEVNVTTNLDFFLNVAQVQLLQQLVEANMIGLEPSSTINEVSKQEQKKMDVSDGGMVETSSRYSGAQDSGIGSDSVKIRIVQIEQHSGTSQHRIAQPSRQSSIVKNLNFIPFDIFVTASRISLMTYSCTALPKLKSPQDQKDGEKISKSSLNLPEAGSGSSHDTKRPSQPSISSVTADDLLNSNVPLSSGRKTGLLSLETLHASTRSSARQALGITIVRQPGRRGTGDIELQPFLYLVVSQPSVLLSCHHRKQKIEVSVFDAGLKGVASDYKCTDPGKTLPEALDYCKIWLQTVAGEVDAKSGIPPSLITVQIKDFLNGPADVNIDVSKPLKANLSFVKLDQLKEFLKKIMTTNDNKPGKETAPSTGTHPDEAVASGAKHSSTKGSPPAVHTSAAQKVSVQENLWQALSCFQKISIHTVQMVVSMETVPHPSKPCLLASLSNLSGSLNIKGGLKTAGIHGSCLVLDIKDFLLKTCLKERTRSLIGPFCCSVTVEAKWCKHSGDPGPEQSIPKMYIDLKGGLLQVFWGQEHLNCLVLLQELVWEYLTKTGSAETFVSERRYRASSSTERNQASKTEHSSDDLRTGLFQYIQDAEAQKLPGAYEVVFYNETEDSPGMMLWRYPEPRVLTLVRINPVPFNTTEDPDISTADLGDVLQIPCSLEYWDELQKSFVAFREFSLSESKVCELQLPNVSLVNDQKELIASDLWRIVLNSNQNVVDDQSSESESGSQSACDQLVTPTALAACTRVDSCFTPWFVPSVSVLVQFSFLEVHLCHHLDQLGTAPPKFLQPFLSDKNMPSELEYMIISFDEPHVYLRQWSDESVFQELQFSTQADCKLLECRNVTMQSVVKPFKIWGQIAISGGTGRRLLDCTIMVDPILILFGQYAIHSLNTAIQAWQQNQCPEAEELVFSHFVICNDTQETLRFGQVDTDENILLASLHSHQYSWRSHKSPQLLHICIEGWGNWRWSEPFSVDNAGTFIRTIQYKGRTASLIIKVQQLSGVQKQILICGRQTVCSYLSESIELKVVQHYISQDGQAVVKEHINCLAAKQKLPSYVLEDDELTELSVKATGDEDWSQDVCLSSEHTEHSTVIQVPSSKSLITYVWCTILTLEPSSHVQQRIIVFSPLFIVRSHLPDPIIIHLEKRSLGLNETQVVPGKGQEKALQNIEPDLTHHLTFQAREEDDPSECAVPISTTLIKQIATKSHPGGNVSQILSEFYGTANPRQPAWPYNKKDSDSSEQLSQWDSPMRVKLSVWKPCVKTLLIELLPWALLINQSKWDLWLFEGEKIVLQVPTGKVMIPPNFEEAFQVGIYWANTNTVHKSVAIKLVHDVTSPKWKDAENGEVVTLDEEGFVEAEIKLGAFPGHQKLCQFCISSMVRQGIQILQIEDKTTIINDTSYQIYYRPQLCISKPYSGEEDFYSADSTVFSVGPARTKNTETLTSVPCWDLLADSSPITSGTPPTQKRMLLSFSPGGSSEFWSLPAVIKQEFPRQSVAVPIGACTESGFYTRAITLTYQEHLGVTYLTLTEDPSPRIIIHNRCSISLLVKENFKDTPKFEVYCRKIPAECSIHHELYHQISSYPDCKTRDLLPSILLKVMSSDDLVNEWSDIVDINNQGTQVVFLTGFGYVYVDIVHQCGTIIITLAPEGRAGPVEINLNRSQEQSLFLKVFISQLSLAVFDDITNHKVSSELLRLTADNVFLHMAPTTSYLRPLSRELQQDTGEGLPPFYSLQVYCEDLQLDNQLYSKSNFHFAVLLCQGEKNETMQWSRANNLIVSNKDLENYKENCFIKLCIAFSEEENFTFHVNDLSFELKPARLYVEDTFVYYIKTLFDTYLPENKGAWQSVNSSDTTQILPKQVREHARALVKPVKLRKLTIQPVNLLVSIHASLKLYIASDHTPLSFSVFERGPIFTTARQLVHALAMHYAAGALFRAGWVVGSLEILGSPASLVRSIGNGIADFFRLPYEGLTRGPGAFVSGVSRGTTSFVKHISKGTLTSITNLATSLARNMDRLSLDEEHYNRQEEWRRQLPENLGEGLRQGLSRLGISLLGAIAGIVDQPMQNFQRVSEGQASAGHKAKGVISGVGKGIMGVFTKPIGGAAELVSQTGYGILHGAGLSQLPKQRSHPNDQQVEQAPNSHVKYVWKMLQSLGKPEVHMALDVMIVSGSGQQHDGCLLLTSEVLFVVSISEDTQQQAFPVTEIDCLEDDQQKDLLKVQLKQQRVPCDLEADGVRERLSEQQYNRLVEYVTKTSYHLAPSTTTVPAPQAVAAEHLPTVTKTYNYVVDPNFAQVFISKFIMVKNKALRKGFY", "length": 4031, "header": "tr|A0A8V0YH92-1|A0A8V0YH92_CHICK Isoform 1 of Vacuolar protein sorting 13 homolog B OS=Gallus gallus OX=9031 GN=VPS13B PE=3 SV=1 CANONICAL=A0A8V0YH92-1" }, "locus": { "chromosome": "2", "start_pos": 127872226, "end_pos": 127462992, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027040.1", "url": "https://www.ensembl.org/id/ENSGALT00010027040.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015387.1", "url": "https://www.ensembl.org/id/ENSGALP00010015387.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A8I5Y7Q0-1", "protein_name": "Vacuolar protein sorting 13 homolog B", "gene_name": "Vps13b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLESYVTPILMSYVNRYIKNLKPSDLQLSLWGGDVVLSKLELKLDVLEQELKLPFTFLSGHIHELRIHVPWTKLGSEPVVITINTMECILKLKDGIQDDHESCGSNSTNRSTAENTKSSTKLRRIQQAAPTDPDLPPGYVQSLIRRVVNNVNIVINNLILKYVEDDIVLSVNITSAECYTVGELWDRAFMDISATDLVLRKAINFSDCTVCLDKRNASGKIEFYQDPLLYKCSFRTRLHFTYDNLNSKMPSVIKIHTLVESLKLSITDQQLPMFIRIMQLGIALYYGEIGNFKDGETEDPACLSKDPLGNLTGTEDETRLDMQYPAPYKGQELYPQDYEEPQGWVSWAWSFVPAIVSYDDGEEDYPGTDPASTMHQQKAHTLKDPIVSVGFYCTKATVTFKLTEMQAENSYYSPQKVKSKEVLCWEQEGTTIEALMMGEAFFDCQIGFVGCRAMCLKGIMGVKDFEEHMDRSETEACFFICGENLSTKGLTYLTNSLFDYRSPENNGTRAEFTLDAAHHKEIHTEIAGMQRFGAFYMDYLYTMEHSSGKGPSSQQDFPSGKNEDFGIVQEKSTKSLVIGPLDCRLDSSAVHRVLKMIVCAMEHEYEPYSRLKPESKDEKEVVLNPEEVASLEEYIPTRHTSVTLLKCTCTIFMAEFNLLDRLLPVIMGGKNASHFTNATNFQSLRPLPSIQILVDKINLEHSVPMYAEQLVHVVSSLTQPSDNLLHYCYVHCYLKVFGFQAGLTCLEQSGSHCLPAPIVPSFSTALYGKRLKLPALWTKRSQTVVTEGIFELPNLTIQATRAQTLLLQAVYQSWFHSGNASSSTVNEALMNEVFQTTGVKSKNPLPTLEGSIQNVELKYCSTSLVKCASGTLGSIKICAKAPGDSGKEKLIPLLQGPSDTRDLHSTKWLNESRKPESLLAPDLIAFTIQVPQYMDYCHHSGAVFLCSVQGLAVNLDPILYTWVIYQPHKRTSRHIQQISFPFCFFQQPVVAVPLVTSVNRRREDELSVGSAPLGKQQSYQASEYASSPIKTKTVTESRPLSVPVKAVMHIHEECRSPEDKMKEFIAILWNAVKSLTLQLDVQSCCVFIPNDSLPSPSTIVSGDIPGTVRSWYHGQTSIPGTLVLCLPQIKIVSAGHKSMEPLQEIPFVIPRPILEEGDAFPWTISLHHFSIYTLLGKQVTLSLVEPMGCTSTLAVTSQQLLPVGPEGRHSFVVCLHVDLESLEIKCSNPQVQLIYELADIMSKVWNKIQKRGHLSPSSVYSDTMAGPVPGSPVRSSVGTAPPDTSTCSPSADIGTTTEGDSIQAADDSPFSDSVTLEQTTSHIGGSSGRVSLWMQWVLPKVTVKLFAPDLEKKDTEVCMVSELEDLSASIDVQDVYTKVKCKIESFSIDHYQSRPGEGWQSGQFEGVFLQCKEKPVTTTKLLDGAHQQHGFLSLTYTKAVTKNVRHKLTSRSERRSFHKLSEGLMDGSPHFLHEILLSAQAFDIVLCFPLLNAIASIFYTKLPKTQREKRKSSGQPMRTHTLTSRNLPLIYINTSVIRIFVPQTEETQSSVTVNQAAKEDTMVLKVGSVSMAPQADNPLGRSVLRKDIYQRALNLGILRDPGSEIEDRQYQIDLQSISIGTAQWDQLKPEKGSGTGGVPTESERNSQNPALEWNMASSIQRHQERRAILTPILTDFSVRITGAPAIIFTKIISPENLHMEEVLVCGHSLEVNITTSLDFFLSVAQVQLLHQLVAANMTGSEPSAKATEISKHEQKKADTFDAGTAETSSGCSGAQDSGIGSDSVRIRIVQIEQHSGASQHRIARPSHQSSIVKNLNFIPFDIFITASRISLMTYSSVALPKCKLPEQKEGGKTGKSSLNLPEVDSDAAKPNQAYISMATAEDPLSTSTSFSSGKKIRVLSLESLHASTRPSARQALGVTVVRQPGRRGTGDLELDLFLHLIVSQPSLLLSCHHRKQRMEISIFDATLKGVASDYKCADPGKTLPEASDYNIVWLQTVPGETDSKSGIPPSLITLHIKDFLNGPADISLDVSKPLKANLSFTKLDQINHFLKKIKKAHSSAHSTETSASSDSMLNRDEPPVSKCYHGKLSKPKVYCDEAQKTSFQENMWRVISCFQKVSVHTTQIVVSMETVPHPHKPCVLASLSNLNGSLSVKAAQKVFGASLGSSFLLNISDALLKTSLKERSRILIGPFSAAVNLEAKWCKHSGNPGPQQSIPKISMDLRGGLLQVFWGQEHLNCLALLHELFDGYLKEEGKSEMPVPESAPQTPSPMEKAQAFKTEQSSDDLRTGIFQYIQDAEPLKLPGMNEVLFYNETEESPGMMLWRYPEPRVLTLIRITPVPFNTTEDPDISTADLGDVLQVPCSLEYWDELQKVFVAFQEFSLSESKVCELQLPDINLVHDQKKLVSSDLWRIVLNNNQNTTDDQSSASESGSQSTCEPLVTPTALAACTRVDSCFTPWFVPSLCVSFQLAHLEFRLCHHLDQLGTASPQHLQPFVSDKNVPSELEYMIISFREPNLYLQQWNSAPVCREIRFSSQVDCKLLECRNVTMQSVVKPFGICGQMALSSSGGQKLLDCTVILDSVLVNFGQHVVHSLSTAIQAWQQNKCPEVEELVFSHFVICNDTQETLRFGQVDTDENILLASLHSHQYSWRSHKSPQLLHICIEGWGNWRWSEPFVVDHTGTFIRTIQYKGRTASLIIKVRPLSGVQKQIIICGRQIICSYLSQSIELKVVQHYIGQDGQAVVREHFDCLTAKQKLPSYILENSELTELCVKAKGDEDWSRDVCLEPKAPEYSTVIQVPTSNSSIIYVWCTVLTLEPNSQVQQRMIVFSPLFIVRSHLPDPIITHLEKRSLGLRETQIIPGRGQENPLHSVEPDLVHHLTFQAREEYDPSDCAVPISTALIKQITTKIQPGSTVNEMLDEFYGSEKSHEPTWPYSQKDSDRNEQLSQWDSPMRVRLSMWKPYVRTLLIELLPWALLINQSKWDLWLFEGEKIVLQVPAGKIIIPPNFQEAFQIGIYWANTNTVHKSLAIKLVHNLTSPKWKDGGNGEVVTLDEEAFVDAEIRLGAFPGHQKLCQFCISSMVQHGIQVIQIEDKTTVINNTPYEIFYKPHLSVSNPYSGKEHLHVPDSATFSICPGGEHPDVKSSSLPCWDIMPDVGPSVLDTTILQKQILLGFSPVPGADSSQCWSLPAIIRREFPRQSVAVPFGTLREDGFCTRAIALTYQEHFGVTYLTLSEDPSPRVVFHNRCPVTILVKENIRDSPKFEVYCKKIPPESSIHHELYHQIISYPDCKTKDLLPSLFLRVDTMEEMPAEWSDPVDINSQGTQVVFLTGFGYVYVDIAQQCGTVFIILAPEGKAGPIFTSASRALERMVTFRMFITQLSLAVSDDLTHQAPSELLRLTLDNVFLHVSPCVPGVLPGEEPPSSFFQLYGVEVYCGDLQLDNQLYSKSSFHFAVLVCRGEKTEPAQYSKVHSLLVSSKDLEDYKENCFIKLCLTVSEGKDFLLDVSEFTFELKPARLYVEDTFVYYIKTLFDTYLPHSRLAGHHAQLRTGKQLLPMQVTQHAKALVNPVKLRKLVIQPVSLLVSIHASLKLYIASDHTPLSFSVFERGPLFTTARQLVHALAMHYAAGALFRAGWVVGSLEILGSPASLVRSIGNGISDFFRLPYEGLTRGPGAFVSGVSRGTTSFVRHISKGTLTSITNLATSLARNMDRLSLDEEHYTRQEEWRRQLPESLSEGLRQGLSRLGISLLGAVAGIVDQPMQNFQKTSETQASAGHKAKGVISGVGKGIMGVFTKPIGGAAELVSQTGYGILHGAGLSQLPKQRCQPTHLYADQAPNSHVKYVWKMLQSLGRPEVHMALDVVLVRGSGQEHEGCLLLTSEVLFVVSISEDTQQQAFPITEIDCAQDTKQKNLLTVQLKQPRVACDVEIDGARERLSEQQFNRLVDYIAKTSCHLAPSCSSMQTCAVVALEPPPATVKTYRYLADPHFAQVFISKLTMVRNKALRKGFL", "length": 4004 }, "evidence": [ { "id": "A0A8V0YH92", "url": "https://omabrowser.org/oma/group/A0A8V0YH92/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1S0N9-1", "protein_name": "Vacuolar protein sorting 13 homolog B", "gene_name": "VPS13B", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MLESYVTPILMSYVNRYIKNLKPSDLQLSLWGGDVVLSKLELKLDVLEQELKLPFTFLSGHIHELRIHVPWTKLGSEPVVITINTMECILKLKDGIQDDHESCGSNSTNRSTTENTKSSVKPRRIQQAAPADPDLPPGYVQSLIRRVVNNVNIVINNLILKYVEDDIVLSVNITSAECYTVGELWDRAFMDISATDLVLRKVINFSDCTVCLDKRNASGKIEFYQDPLLYKCSFRTRLHFTYDNLNSKMPSVIKIHTLVESLKLSITDQQLPMFIRIMQLGIALYYGEIGNFKDGETEESACHNKDVLGNVTGAEDETRLDMQYPSQYKGQELYSQQEDEQPQGWVSWAWSFVPAIVSYDDGEEDYLGNDPTSTTHQQKAQTLKDPIVSIGFYCTKATVTFKLTEMQAESSYYSPQKVKSKEVLCWEQEGTTVEALMMGEPFFDCQIGFVGCRAMCLKGIMGVKDFEENMNRSETEACFFICGENLSIKGLTYLTNSLFDYRSPENNGTRAEFILDAASHKETYTEIAGMQRFGAFYMDYLYTMENTNGKGSANQQDFSSGRSEDLGTVQEKSTKSLVIGPLDFRLDSSAVHRILKMIVCSLEHEYEPYSRLKPDTKDESETVLNPEEVASLEEYIPTRHTSVTLLKCTFTIFMAEFNLLDHLLPVIMGEKNSSNFMNTTNFQSLRPLPSIQILVDKINLEHSVPMYAEQLVHVVSGLTQPSDNLLHYCYAHCYLKIFGFQAGLTSLDCKGSYCLPVPIIPSFSTALYGKLLKLPTCWAKRSQIAITEGIFELPNLTIQATRAQTLLLQAIYQSWSHTGNVSSLAVNEALMNEVFQSIGVKSKNPLPTLEGSIQNVELKYCSTSLVKCASGTMGSIKICAKAPGDNGKEKLIPLLQGPSDTKDLHSSKWLNESRKPESLLAPDLIAFTVQVPQYMDYCHSSGAVLLCSIQGLAVNIDPILYTWLIYQPQRRTSKHMQQQPVIPVPLVVPISRRKEDEVSVGSAPLAKQQSYQASEYASSPIKTKTVTESRPLSVPMKAMLNISEGCRSPEERMKEFIGVVWNAVKSLTLQLEVQSCCVFIPNDSLPSPSTIVSGDIPGTVRSWYHGQTSMPGMLVLCLPQIKIVSAGHKYMEPLQEIPFVIPRPILEEGDAFPWTISLHHFSIYTLFGKQVTLCLVEPMGCTSTLAVTSQKLLTAGPDTRHSFVVCLHVDLESLEIKCSNPQVQLLYELTDIMNKVWCKIQRRGNLSPSSAHPESLAGPVPSSPVRSSIGTAPPDTSTCSPSADIGTTTEGDSVQALDDSPFSDSVTLEQTTSNIGGSSGRISLWMQWVLPKITIKLFAPDPENKGTELCMVSELEDLSASIDVQDVYTKVKCKIESFNIDHYRSRPGEGWQSGHFEGVFLQCKEKPVTTAKLLDGSHQQHGFLSLTYTKAVTKNVRHKLTSRNERRSFHKLSEGLTDGSPHFLHEILLSAQAFDIVLCFPLLNAIASIFQAKLPKTQKEKRKSPGQPMRTHTLTSRNLPLIYINTSVIRIFVPKTEEVQPSIEVNQAAKEDTMVLKIGSVAMAPQADNPLGRSVLRKDIYQRALNLGILRDPGSEIEDRQYQIDLQSINIGTAQWDQLKPEKESGTGGVLTENERNSQNPALEWNMASSIRRHQERRAILTPILTDFSVRITGAPAIIFTKIISPENMHTEEILVCGHSLEVNITTNLDFFLSVAQVQLLHQLIVANMTGLAPSSKATEISKQEQKKMDAYDGSMAETSSRYSGAQDSGIGSDSVKIRIVQIEQHSGTSQHRIARPSRQSSIVKNLNFIPFDIFITASRISLMTYSCTALPKSKSQEQKDNEKTGKSSLNLPEVDSDITKPSQACISMVTADDLLSSNVSFPSGKKIGVISLESLHASTRSSARQALGVTIVRQPGRRGTGDLQLEPFLYFIVSQPSLLLSCHHRKQRVEVSIFDAVLKGVASDYKCTDPGKTLPEALDYCTVWLQTVPGEIDSKSGIPPSLVTLQIKDFLNGPADIHLDISKPLKANVSFTKLDQINNFLKKIQSAHCRETSALSDTMPNKDELPASRCYRGKLSKLKVHGDGTQKIPFTENVWKTVSCFQKISVHTTQLVVSMETVPHPNKPCLLASLSTFSGSLNVKATQKVPGVILGSSFVLSVNDFLLKTSLKERSRVLIGPCCATANLEAKWCKHSGNPGPEQSIPKISIDLRGGLLQVFWGQEHLNCLVLLHELLNGYLNEEGAFDVQASEAVPQMPSPKEKNQMFKGEQSSDDLRTGLFQYIRDAEPLKMPGVYEVLFYNETEDSPGMMLWRYPEPRVLTLVRITPVPFNTTEDPDISTADLGDMLQIPCSLEYWDELQKVFVAFREFSLSESKVCELQLPDINLVNDQKKLVSSDLWRIVLNSSQNGADDQSSASESGSQSACDQLVTPTALAACTRVDSCFTPWFVPSLCISFQFSHLEFHLCHHLDQLGTAPPQYLQPFVSDKNVPTELEYMIISFREPHIYLRQWNNSSVCQEIQFSAHADCKLLECRNVTMQSLVKPFSIFGQVAVSSSAAEKLIDCAIVIDSVFVNFGQHVVHSLNTAVQAWQQNKCPEVEELVFSHFVICNDTQETLRFGQVDTDENILLASLHSHQYSWRSHKSPQLLHICIEGWGNWRWSEPFSVDHAGTFIRTIQYKGRTASLIIKVQQLSGVQKQIIICGRQIICSYLSQSIELKVVQHYIGQDGQAVVREHFDCLTAKQKLPSYILENSELTELCVRAKGDEDWSRDVCLESKAPEYSVVIQVPSSNSSIIYVWCTVLTLEPSSQVQQRMIVFSPLFIMRSHLPDPIIIHLEKRSLGLSETQVIPGKGQEKPLQNIEPDLVHHLTFQAREEDDPSHCAVPISTSLIKQIATKIHPGGTVNQILDEFYGPEKSLQPTWPYNKKDSDRNEQLSQWDSPMRVKLSAWKPYVRTLLIELLPWALLINQSKWDLWLFEGEKIILQVPAGKIIIPPNFQEAFQIGIYWANTNTVHKSVAIKLVHNLTSPKWKDGGNGEVVSLDEEGFVDAEITLGAFPGHQKLCQFCISSMVQQGIQVIQIEDKTTIINNTPYQIFYKPQLSVSTPQSGKEYFHIPDGATFSLHPGGEQPAVTFSSLPCWDLRPDISQSALDASLLQKQILLAFAPAAAANSSQYWSLPAVVRQEFPRQSVAVPLGSCGENGFCTRAIALTYQEHFGVTYLTLSEDPSPRIIFHNRCPVTILIKENIKDIPKFEVYCRKIPPECSVHHELYHQMSSYPDCKTRDLLPSLLLRVELLEEMTTEWSDAIDINNQGTQVVFLTGFGCVYVDTVHQGGTIFITVAPEGKAGPILTNTHRTPEKIMALRMVITQLSVAVLDDLTHHRVSSELLRLTLDNVFLRLAPVAGHLPGEEAAAAPVHLYCVEVCCGDLQLDNQLYNKSNFHFAVLVCQGEKTEPSPCAKMQSLLVSSHDLEEYRKKCFIKFCLTLAEGKSCSFDINEFSFELKPARLYVEDTFVYYVKTLFETYLPSGGPATHAPLLAGGTQGLPLQVRQHARALVHPVRLRKLVIQPVNLLVSIHASLKLYIASDHTPLSFSVFERGPIFTTARQLVHALAMHYAAGALFRAGWVVGSLEILGSPASLVRSIGNGIADFFRLPYEGLTRGPGAFVSGVSRGTTSFVKHISKGTLTSITNLATSLARNMDRLSLDEEHYNRQEEWRRQLPESLGEGLRQGLSRLGISLLGAIAGIVDQPMQNFQKTSEAHASAGHKAKGVISGVGKGIMGVFTKPIGGAAELVSQTGYGILHGAGLSQLPKQRYQPGDLHADQAPNSHAKYVWKMLQSLGRPEVHMTLDVVLVRGSGQEHEGCLLLTSEVLFVVSVSEDTQQQAFPVTEIDCAQDSKQSNLLIVQLKQPRVACDVEVDGTRERLSEQQYNRLVDYITKTSCHLAPSCSFVQTPCPVVAVEPLPSTVKTYHYMVDPPFAQVFISKFTMVKNKALRKGFP", "length": 3993 }, "evidence": [ { "id": "A0A8V0YH92", "url": "https://omabrowser.org/oma/group/A0A8V0YH92/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q7Z7G8-1", "protein_name": "Intermembrane lipid transfer protein VPS13B", "gene_name": "VPS13B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLESYVTPILMSYVNRYIKNLKPSDLQLSLWGGDVVLSKLELKLDVLEQELKLPFTFLSGHIHELRIHVPWTKLGSEPVVITINTMECILKLKDGIQDDHESCGSNSTNRSTAESTKSSIKPRRMQQAAPTDPDLPPGYVQSLIRRVVNNVNIVINNLILKYVEDDIVLSVNITSAECYTVGELWDRAFMDISATDLVLRKVINFSDCTVCLDKRNASGKIEFYQDPLLYKCSFRTRLHFTYENLNSKMPSVIKIHTLVESLKLSITDQQLPMFIRIMQLGIALYYGEIGNFKEGEIEDLTCHNKDMLGNITGSEDETRIDMQYPAQHKGQELYSQQDEEQPQGWVSWAWSFVPAIVSYDDGEEDFVGNDPASTMHQQKAQTLKDPIVSIGFYCTKATVTFKLTEMQVESSYYSPQKVKSKEVLCWEQEGTTVEALMMGEPFFDCQIGFVGCRAMCLKGIMGVKDFEENMNRSETEACFFICGDNLSTKGFTYLTNSLFDYRSPENNGTRAEFILDSTHHKETYTEIAGMQRFGAFYMDYLYTMENTSGKGSTNQQDFSSGKSEDLGTVQEKSTKSLVIGPLDFRLDSSAVHRILKMIVCALEHEYEPYSRLKSDIKDENETILNPEEVALLEEYIPTRHTSVTLLKCTCTISMAEFNLLDHLLPVIMGEKNSSNFMNTTNFQSLRPLPSIRILVDKINLEHSVPMYAEQLVHVVSSLTQPSDNLLHYCYVHCYLKIFGFQAGLTSLDCSGSYCLPVPVIPSFSTALYGKLLKLPTCWTKRSQIAITEGIFELPNLTIQATRAQTLLLQAIYQSWSHLGNVSSSAVIEALINEIFLSIGVKSKNPLPTLEGSIQNVELKYCSTSLVKCASGTMGSIKICAKAPVDSGKEKLIPLLQGPSDTKDLHSTKWLNESRKPESLLAPDLMAFTIQVPQYIDYCHNSGAVLLCSIQGLAVNIDPILYTWLIYQPQKRTSRHMQQQPVVAVPLVMPVCRRKEDEVSIGSAPLAKQQSYQASEYASSPVKTKTVTESRPLSVPVKAMLNISESCRSPEERMKEFIGIVWNAVKHLTLQLEVQSCCVFIPNDSLPSPSTIVSGDIPGTVRSWYHGQTSMPGTLVLCLPQIKIISAGHKYMEPLQEIPFVIPRPILEEGDAFPWTISLHNFSIYTLLGKQVTLCLVEPMGCTSTLAVTSQKLLATGPDTRHSFVVCLHVDLESLEIKCSNPQVQLFYELTDIMNKVWNKIQKRGNLNLSPTSPETMAGPVPTSPVRSSIGTAPPDTSTCSPSADIGTTTEGDSIQAGEESPFSDSVTLEQTTSNIGGTSGRVSLWMQWVLPKITIKLFAPDPENKGTEVCMVSELEDLSASIDVQDVYTKVKCKIESFNIDHYRSSLGEECWSLGQCGGVFLSCTDKLNRRTLLVRPISKQDPFSNCSGFFPSTTTKLLDGTHQQHGFLSLTYTKAVTKNVRHKLTSRNERRSFHKLSEGLMDGSPHFLHEILLSAQAFDIVLYFPLLNAIASIFQAKLPKTQKEKRKSPGQPMRTHTLTSRNLPLIYVNTSVIRIFIPKTEEMQPTVEANQAAKEDTVVLKIGSVAMAPQADNPLGRSVLRKDIYQRALNLGILRDPGSEIEDRQYQIDLQSINIGTAQWHQLKPEKESVSGGVVTETERNSQNPALEWNMASSIRRHQERRAILTPVLTDFSVRITGAPAVIFTKVVSPENLHTEEILVCGHSLEVNITTNLDFFLSVAQVQLLHQLIVANMTGLEPSNKAAEISKQEQKKVDIFDGGMAETSSRYSGAQDSGIGSDSVKIRIVQIEQHSGASQHRIARPSRQSSIVKNLNFIPFDIFITASRISLMTYSCMALSKSKSQEQKNNEKTDKSSLNLPEVDSDVAKPNQACISTVTAEDLLRSSISFPSGKKIGVLSLESLHASTRSSARQALGITIVRQPGRRGTGDLQLEPFLYFIVSQPSLLLSCHHRKQRVEVSIFDAVLKGVASDYKCIDPGKTLPEALDYCTVWLQTVPGEIDSKSGIPPSFITLQIKDFLNGPADVNLDISKPLKANLSFTKLDQINLFLKKIKNAHSLAHSEETSAMSNTMVNKDDLPVSKYYRGKLSKPKIHGDGVQKISAQENMWRAVSCFQKISVQTTQIVISMETVPHTSKPCLLASLSNLNGSLSVKATQKVPGIILGSSFLLSINDFLLKTSLKERSRILIGPCCATANLEAKWCKHSGNPGPEQSIPKISIDLRGGLLQVFWGQEHLNCLVLLHELLNGYLNEEGNFEVQVSEPVPQMSSPVEKNQTFKSEQSSDDLRTGLFQYVQDAESLKLPGVYEVLFYNETEDCPGMMLWRYPEPRVLTLVRITPVPFNTTEDPDISTADLGDVLQVPCSLEYWDELQKVFVAFREFNLSESKVCELQLPDINLVNDQKKLVSSDLWRIVLNSSQNGADDQSSASESGSQSTCDPLVTPTALAACTRVDSCFTPWFVPSLCVSFQFAHLEFHLCHHLDQLGTAAPQYLQPFVSDRNMPSELEYMIVSFREPHMYLRQWNNGSVCQEIQFLAQADCKLLECRNVTMQSVVKPFSIFGQMAVSSDVVEKLLDCTVIVDSVFVNLGQHVVHSLNTAIQAWQQNKCPEVEELVFSHFVICNDTQETLRFGQVDTDENILLASLHSHQYSWRSHKSPQLLHICIEGWGNWRWSEPFSVDHAGTFIRTIQYRGRTASLIIKVQQLNGVQKQIIICGRQIICSYLSQSIELKVVQHYIGQDGQAVVREHFDCLTAKQKLPSYILENNELTELCVKAKGDEDWSRDVCLESKAPEYSIVIQVPSSNSSIIYVWCTVLTLEPNSQVQQRMIVFSPLFIMRSHLPDPIIIHLEKRSLGLSETQIIPGKGQEKPLQNIEPDLVHHLTFQAREEYDPSDCAVPISTSLIKQIATKVHPGGTVNQILDEFYGPEKSLQPIWPYNKKDSDRNEQLSQWDSPMRVKLSIWKPYVRTLLIELLPWALLINESKWDLWLFEGEKIVLQVPAGKIIIPPNFQEAFQIGIYWANTNTVHKSVAIKLVHNLTSPKWKDGGNGEVVTLDEEAFVDTEIRLGAFPGHQKLCQFCISSMVQQGIQIIQIEDKTTIINNTPYQIFYKPQLSVCNPHSGKEYFRVPDSATFSICPGGEQPAMKSSSLPCWDLMPDISQSVLDASLLQKQIMLGFSPAPGADSSQCWSLPAIVRPEFPRQSVAVPLGNFRENGFCTRAIVLTYQEHLGVTYLTLSEDPSPRVIIHNRCPVKMLIKENIKDIPKFEVYCKKIPSECSIHHELYHQISSYPDCKTKDLLPSLLLRVEPLDEVTTEWSDAIDINSQGTQVVFLTGFGYVYVDVVHQCGTVFITVAPEGKAGPILTNTNRAPEKIVTFKMFITQLSLAVFDDLTHHKASAELLRLTLDNIFLCVAPGAGPLPGEEPVAALFELYCVEICCGDLQLDNQLYNKSNFHFAVLVCQGEKAEPIQCSKMQSLLISNKELEEYKEKCFIKLCITLNEGKSILCDINEFSFELKPARLYVEDTFVYYIKTLFDTYLPNSRLAGHSTHLSGGKQVLPMQVTQHARALVNPVKLRKLVIQPVNLLVSIHASLKLYIASDHTPLSFSVFERGPIFTTARQLVHALAMHYAAGALFRAGWVVGSLDILGSPASLVRSIGNGVADFFRLPYEGLTRGPGAFVSGVSRGTTSFVKHISKGTLTSITNLATSLARNMDRLSLDEEHYNRQEEWRRQLPESLGEGLRQGLSRLGISLLGAIAGIVDQPMQNFQKTSEAQASAGHKAKGVISGVGKGIMGVFTKPIGGAAELVSQTGYGILHGAGLSQLPKQRHQPSDLHADQAPNSHVKYVWKMLQSLGRPEVHMALDVVLVRGSGQEHEGCLLLTSEVLFVVSVSEDTQQQAFPVTEIDCAQDSKQNNLLTVQLKQPRVACDVEVDGVRERLSEQQYNRLVDYITKTSCHLAPSCSSMQIPCPVVAAEPPPSTVKTYHYLVDPHFAQVFLSKFTMVKNKALRKGFP", "length": 4022 }, "evidence": [ { "id": "A0A8V0YH92", "url": "https://omabrowser.org/oma/group/A0A8V0YH92/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q80TY5-1", "protein_name": "Intermembrane lipid transfer protein VPS13B", "gene_name": "Vps13b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLESYVTPILMSYVNRYIKNLKPSDLQLSLWGGDVVLSKLELKLDVLEQELKLPFTFLSGHIHELRIHVPWTKLGSEPVVITINTMECILKLKDGIQDDHESCGSNSTNRSTAENTKSSIKPRRIQQAAPADPDLPPGYVQSLIRRVVNNVNIVINNLILKYVEDDIVLSVNITSAECYTVGELWDRAFMDISATDLVLRKAINFSDCTVCLDKRNASGKIEFYQDPLLYKCSFRTRLHFTYDNLNSKMPSVIKIHTLVESLKLSITDQQLPMFIRIMQLGIALYYGEIGNFKDGETEDPPCLSKDTLANLTGTEEESRIDMQYPAPYKGQELYSQDYEEPQGWVSWAWSFVPAIVSYDDGEEDDLGTDPASIMHQQKAQTLKDPIVSVGFYCTKATVTFKLTEMQAENSYYSPQKVKSKEVLCWEQEGTTIEALMMGEPFFDCQIGFVGCRAMCLKGILGVKDFEEHMNRSETEACFFICGENLSTKGLTYLTNSLFDYRSPENNGTRAEFILDAAHHKETHTDIAGIQRFGAFYMDYLYTVEHSSGKGPTSQQDFPSGKNEDLGIVQEKSTKSLVIGPLDCRLDSSAVHRVLKMIVCALEHEYEPYSRLKPESKDEKETVLDPEEVSSLEEYIPTRHTSVTLLKCTCTVFMAEFNLLDCLLPVIMGGKNSSNVTNATNFQSLRPLPSIQILVDKINLEHSVPMYAEQLVHVVSSLNQPSDNLLHYCYVHCYLKVFGFQAGLTCLDHSGSYCLPAPIIPSFSTALYGKLLKLPALWTKRSQTVVTEGIFELPNLTIQATRAQTLLLQAIYQSWSHIGNVSSSTVNEALMNEVFPMTGVKSKNPLPTLEGSIQNVELKYCSTSLVKCASGTLGSIKICAKAPGDSGKEKLIPLLQGPSDTRDLHSSKWLNESRKPESLLAPDLIAFTIQVPQYMDYCHHSGAVFLCSVQGLAVNIDPILYTWVIYQPQKRANRHAQQQPVVAVPLVTSVNRRKEDELSIGSAPLGKQQSYQASEYASSPIKTKTVTESRPVSVPVKAVLRVHEECRSPEDKMKEFIAILWNAVKSLTLQLDVQSCCVFIPNDNLPSPSTIVSGDIPGTVRSWYHGQTSIPGTLVLCLPQIKIISAGHKYMEPLQEIPFVIPRPILEEGDAFPWTISLHHFSIYTLLGKQVTLSLVEPMGCTSTLAVTSQKLLPVGPDGRHSFVVCLHVDLESLEIKCSNPQVQLIYELADTMSKVWSKIQKRGNLSPSSVYPETVAGPIPGSPVWSSVGTAPPDTSTCSPSADIGTTTEGDSVQAGDDSPFSDSVTLEQTTSNIGGSSGRVSLWMQWVLPKATVKLFAPDLEKKGTEVCMVSELEDLSASIDVQDVYTKVKCKVESFSIDHYQSRPGEGWQSGHFEGVFLQCKEKPVTTTKLLDGAHQQHGFLSLTYTKAVTKNVRHKLTSRNERRSFYKLSEGLMDGSPHFLHEILLSAQAFDIVVCFPLLNAIASVFHTKLPKTQREKRKSSGQPMRTHTLTSRNLPLIYINTSVIRIFVPQTEETQSTVAVNQAAKEDTMVLKVGSIAMAPQADNPLGRSVLRKDIYQKALNLGILRDPGSEIEDRQYQIDLQSINIGTAQWDQLKPEKGSGSGGVPTESERNSQNPALEWNMASSIQRHQERRAILTPILTDFSVRITGAPAIIFTKIISQENLHMEEILVCGHSLEVNITTNLDFFLSVAQVQLLHQLIVANMTGLEPSTKATEISKQEQKKVDTFDGGTAETSSRYSGAQDSGIGSDSVKIRIVQIEQYSGASQHRIARPSHQSSIVKNLNFIPFDIFITASRISLMTYSSVALPKFKLPEQKEDGKTGRTFLNLAEVDSDVAKPNQACVSMVTAEDPLSSSTSFSSGKKVRVLSLESLHASTRSSARQALGVTVVRQPGRRGTGDLELDLFLHLIVSQPSLLLSCHHRKQRVEVSIFDAMLKGVPSDYTCTDPGKTLPEASDYNIVWLQTVPGETDSKSGIPPSLVTLHIKDFLNGPADIYLDVSKPLKANLSFTKLDQINHFLKKIKKAHSSAHSKETSTPSDSILNMDEPPVPKCYRGKLSKTKVHCDEAQKTSFQENIWRAISCFQKVSVHTTQIVVSMETVPHPHKPCVLASLSNLNGSLTVKAAQKVPGASLGSSFLLSIHDVLLKTSLKERSRILIGPFSATVNLEAKWCKHSGNPGPQQSIPKISMDLRGGLLQVFWGQEHLNCLALLHELFNGYLQEGKSEMPVPESAPQMPSPVEKTQAFKTEQSSDDLRTGIFQYVQDAESLKLPGVYEVLFYNETEESPGMMLWRYPEPRVLTLVRITPVPFNTTEDPDISTADLGDVLQVPCGLEYWDELQKVFVAFQEFSLSESKVCELQLPDINLVHDQKKLVSSDLWRIVLNNNQNTTDDQSSASESGSQSTCEPLVTPTALAACTRVDSCFTPWFVPSLCMSFQFAHLEFRLCHHLDQLGTASPQYLQPFISDKNVPSELEYMIISFREPNLHLRQWNSGPVCQEIKFSSQMDCKLLECRNVTMQTVVKPFGICGQMALSSDGVQKLLDSTVIVDSVLVNFGQHVVHSLNTAIQAWQQNKCPEVEELVFSHFVICNDTQETLRFGQVDTDENILLASLHSHQYSWRSHKSPQLLHICIEGWGNWRWSEPFTVDHAGTFIRTIQYKGRTASLIIKVRALSGVQKQIIICGRQIICSYLSQSIELKVVQHYIGQDGQAVVREHFDCLTAKQKLPSYILENNELTELCVKAKGDEDWSRDVCLEPKASEYSTVIQVPTSNSSIIYVWCTVLTLEPNSQVQQRMIVFSPLFIMRSHLPDPIIIHLEKRSLGLSETQIIPGRGQENPLQNVEPDLVHHLTFQAREEYDPSDCAVPISTALIKQIATKIQPGGTVNEMLDEFYGPEKSQEPTWPYSNKDSDRNEQLSQWDSPMRVKLSIWKPYVRTLLIELLPWALLINQSKWDLWLFEGEKIVLQVPAGKIIIPPNFQEAFQIGIYWENTNTVHKTLAIKLVHNLTSPKWKDGGNGEVVTLDEEAFVDAEIRLGAFPGHQKLCQFCISSMVQHGIQVIQIEDKTTVINNTPYQIVYKPHLAISNSYSGKEHCHVPDSATFSICPGGEHPAVRSSSLPCWDVTPAVGSSELDTATLQKQILLGFSPVPGADSAQCWSLPAIIGGEFPRQSVAVPFGTGRENGFCTRAIALTYQEHLGVTYITLSEDPSPRVVFHNRCPVPMLMKENIRDIPKFDVYCKKIPPESSVHHELYHQIISYPDCKTKDLLPSLFLRIDSMEEMTAEWSDPVDINSQGTQVVFLTGFGYVYVDIAQQCGTVFIILAPEGKAGPIFTSTSRALERMVTFRMFITQLSLAVSDDLTHQAPSELLRLTLDNVFLHVSPVPALLPGEEPPSSFFQLYGVEVYCGDLQLDNQLYNKSNFHFAVLVCQGERTDPAQYSRVQSLLVSSKALEEYKENCFIKLCLTVSEGKDILLDVSEFTFELKPARLYVEDTFVYYIKTLFDTYLPPSRMSGHHAQLFTGQQVLPVQVTQHAKALVNAVKLRKLLIQPVNLLISIHASLKLYIASDHTPLSFSVFERGPVFTTARQLVHALAMHYAAGALFRAGWVVGSLEILGSPASLVRSIGNGISDFFRLPYEGLTRGPGAFVSGVSRGTTSFVKHISKGALTSITNLATSLARNMGRLSLDEEHYNRQEEWRRQLPESLGEGLRQGLSRLGISLLGAIAGIVDQPMQNFQKTSETQASAGHKAKGVISGVGKGIMGVFTKPIGGAAELVSQTGYGILHGAGLSQLPKQRCQPTHLYADQAPNSHVKYVWKMLQSLGRPEVHMALDVVLVRGSGQEHEGCLLLTSEVLFVVSISEDTQQQAFPITEISCAQDTKQNNLLTVQLKQPRVASDVEIDGARERLSEQQFKRLVDYIAKTSCHLAPSCSSMQTCSVVAVEPPPATVKTYHYLVDPHFAQVFISKFTMVKNKALRKGFS", "length": 3993 }, "evidence": [ { "id": "A0A8V0YH92", "url": "https://omabrowser.org/oma/group/A0A8V0YH92/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VAD3-1", "protein_name": "Vacuolar protein sorting 13B, isoform A", "gene_name": "Vps13B", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MFKLESYITPILLSYVAKYVKNFRDEDAQVSLWEGEVTFQNLDLRLEVLEEELNLPVELVSGHIHELSILVPWTKLMSEPVKIVINTIEFVAKLPDSESKQRRASFQREQRRKSKRESVEQPDQTKSPGPASSSSVVNKIINNINLQCHNIILKYVEDDIVVSMNVQTLNFSSAGEDWKPTMVDIHPVSVVMRKLLQVSDLTICLDKRNTAGRIEVCQEPVLYRCTLECRVLRKYNANTVSTTSTTRIGVFTKSLDINVSSLQFPMVMRLVKMLLELKPAEFEDDPQNPEDQEAVAEGSESQQGTESAGRSVFWWAWSLLPSFDTEAPSSSCDTPTGHAFDLGVYAEELNFQLKNSEYFTDQSMGGIKRIRYTPILRISLGGLYYERTILKECDWANVKAGLSSMCMEPLGAYRSDDLVDRNLVNTQEFQQERSFIDKSLFDENYMFAERSWCSYNYADYVARNTDEYMLFRSPVLAFDVIEHRVPKPSSHPVAESQLRDLGVRIQYRLLSAGITFHFSQSFVQVKKVISDLIRPYDYPGYRSESMKDEDRGVPEPENKNSEMTIPDLEYLMGLVPTCNYKIELRNIVVQLYPRQQQDESSAINQHQLTTTVRQSLLPYLQLKISLVEGTMCGPVNPVRLVQLITHLEEKPRDVVNACYNCFHFNVKNLALMIMNTTPDNGRAKLLNIPRVQVNWNRLLAPHLWRQNEAPLETSEIKSEIITLEFSKRELIIAKRLVPLISSFSGQDLCDLAHIVANVNVNSDVIKLQSVGTKLNLVYHKYHTHLAAVGSLQGVHTDAVHTKMNIRNVVLSTSKNADNKWLEMQCQFPLEEVHSEQEKIPGTVVCLWLEPFRITTDIYLLQFLNFSDNSGRQITKDKEVETDLESVNQSEPPITQSVSNYSTISASAIAFNDFQPRRISRNNSRKISVPEETVHLSSERDERHTQAEPLTIPVANKPQPSNFDTTDFVKRLTKMVVLVEIAQAKIDVCEVMMRKTPGHTDVEYTSIRLPHMKVKSGNCEAIQRGNIRGVIPVASNTELLNWVFDLNEFNVCYRRANVTEMIIAPVRTTITLALSFKTSDKVDGSKGKEDKCANTCSINVHVDMSAINIFAQRVKLLHEHCLIISKMYGSLCPDEPASKWQTGKMKPRLEVYTGSAQNYPVIKEFLELDPNFEAPKVKSAPKSSVILFCQWTIPRISFEMENSNDFKHSKIVMSLEDLLLNIDKHSDFNKITTKIENFGLNYYEEKHEEWEKIDDLHIKMLGDSTNLPLISVVITTVSLEDLYAKIGARNPHNKQHTISEVLIEVQPIEMVLNLDQITEFMVPICEVLEIIGNSASAQSANKPSAPVPSKITTVQDLPMVHLNSKGIYVYLPLSTGKKSCSVLLLRIESIQLTPSLENPLVRQLVRPDIYQKAAELNMLSTPGALVEDRQYELSVRRVSLSTGNWKQTQEYRIEKTLASKHDNPAFEWNNQSQSTELDHMEIFKDFDFIMIYAPAISYDRFLVCGQSVEYNCATDFVASLNTHQISLISCIIVRAQRLGCIIDQVCVKNAELPKARSHKTLGNISKYNSVDNSIYFPADPKVFKKDTWIPKSSKKLVSERLSYTNASTSFTDAKGSSDYFYGSCQSDSGIHLGTRMKGYSRSLAAEEINRSGRQPFVLSYPSSVSFVAGIFVLKIYDVLELEELERPVMKPLFLMTVSQPSFMSTQNFKAAVTQASIFNVNISVAKADVDGKVDSERFNESVFATLPGQLGSSGIPPPLLTIKTQYDRLHQKEVDVELRKPILLRICENTIKQLASDVFRIYTVLHETPCFNVRSPRPVPEGSQLRQLKMNCYNADRFHLSCDRITAKFYDEERSYKCSFVWLDVSTRIKFSSRPQKAVIRSNIGSFYVQSGEKMLLHPLLMRLSVDLVSEPWSEELLVNATLKLNYLHIDAGVFSILQLQKAQQGVNRIREYADREWQQFLRSRPVLGTPKDVSPCNLIKCTPSHESIERIKRPLKSNAEFYQDDLRAGAFQFVYLNSESVLPMPYQVQIIKKNYGIICWRYPQPRQMTSIHIYPVPMPVSRPIHIRCRMEYFSETHETFLHYCDFMLSETSTKQLTPPDRPICATIWRVVILQSLISVDGTCFEGSEDEDLSIEYLQSDFKVDENNDFILHPKVLVGCMRIDTVFRAEKVPKLQLLLCCQDIELNFVNQTDNTGELPKQLNKYRLRQTPNITQTFLTVHVEDLQMHSRIYSRNDFSLQTEMRARVKCLDYGFLNMLDVLEPMKFSSYVRLTDYPRSLVQANFLVDKLRLNCGPHVIHTLLSSKYHWQEVLQQKDVRHVLMPKLVIVNRIQTPISFGQTNTVEKIPVNPGEVQLYHFRSCSHVQELTFFITNPKTLLVDSSDSVHIALKFEDEEKIHNLRVGEYCITLKLAKLSTTQIYILVKGQIELVSMVPFNLVTEFREEEINYDESTPPEHLLLSKERSSYYQNVKRNADINMRLKLTAGLGRGRTGDIPLKTNNNLPWLVKVPTQSAQQFISIWVRILREDIKMDKPAEDFQPQKILICIWPIFEICNMLSCAVKATESTTGESSTIEAMGGRWALNTATTHATEHNIGFTFSGILRGSSKDEYSLMLRTMDWHKFFYYDPTVWTIENALHKLGKSSKRKWPLNDPEELRVSRVLDFENAFDVKYQTKATREFSCCQGLDVTAWGMFINGTGLYVAIFMIQEQARLDLKANSLQMMPKLKSAFTIDVRFDNGWKSSTPICLEDFTQKSSSNAGRSLYLRYNSFVDIVIVERDEVLRLILEYRQEDDGRRLFKLRSKFVFTNFTDVVLNALTLAMDHKENSTREEVEAYSICKKARSLVSSESTKNCSGNAMDVFYDLNAHKAKHNCDTAFVYFVCFSVGGSREISIPIPLAVPFTRRCFSLQAGPESIPLMITLIEKDNVHYLNVFRDTAPAIVISNNTNVKFIVAQTSASENSNVSCTNSEFVGRNFEWNQLVLPHSNCYYTPPQMYANFPDVEFTMCNLSLAVYKDKLCAKNKIAWSKPIRTDKSWQKFLHVPHHGDVKVVVCDKHRAIRLNIYYIAQQLEFSVKDLRSRLTKPENVLMPSQEQAAPRPDESSEQENDTKRVTLPNMVTCAHFNEECESKTQTRIKIFIKSFVFSLQTDNRENDFVKTEVCNIYADDSMLIYDDDDDQRELRLQLPNLQVDNQLYSSGKYDFPVLLCAEKLYRRNCSLPQVYDLDHVYKQQAQRTPVSLFTFIFYQDEMQLQNVRCQIPPFRVYIEDAYLNQLLEALVECEPSNCVYSPPVEQDQILLPAGMTLLPDQVVAQSLYISEPLRLNSFTVEPLNLLLSVHTSSRLYIALDHSPLSFSRYERQQILTVPLRFGQSLGLHYLSGAIFGAGWVVGSLEILGSPSGLARSFSTGLRDFVSMPVQGLFRGPWGFLVGVTQGSASLLRNVTAGTVNSVTKLAGSVARNLDRLTLDAEHIELTEARRRARPQGFADGLTQGLTGLGISLLGAVGGLAHHTLEARSSVGVIAGLTKGIVGALTKPISGAAEMLALTGQGVLHTVGFNAMPQQVEPSFIRNVALHGSSNRIWSYLPEELSRDQMLFFSEIMLQISTQLRPALLFLTSSVLAIMQSDSEDLAFASPISKVDVLADREDPSKLYLSLKSERRDDFEGQLNYTNERIMKFLNASRLQSIANDSLNDLLQLHELDVDDRIQRQSQCIFYIKPNIGEHLIHYLKVISRIQH", "length": 3731 }, "evidence": [ { "id": "A0A8V0YH92", "url": "https://omabrowser.org/oma/group/A0A8V0YH92/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YH92", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH92" } ], "pmid": "" }, { "name": "acrosomal membrane", "id": "GO:0002080", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002080", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YH92", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH92" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 7, "go_terms": [ { "name": "lipid transport", "id": "GO:0006869", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006869", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YH92", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH92" } ], "pmid": "" }, { "name": "adipose tissue development", "id": "GO:0060612", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060612", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YH92", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH92" } ], "pmid": "" }, { "name": "central nervous system development", "id": "GO:0007417", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007417", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YH92", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH92" } ], "pmid": "" }, { "name": "acrosome assembly", "id": "GO:0001675", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001675", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YH92", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH92" } ], "pmid": "" }, { "name": "Golgi organization", "id": "GO:0007030", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007030", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YH92", "url": 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"count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YHC6-1", "uniprot_ac": "A0A8V0YHC6", "uniprot_id": "A0A8V0YHC6_CHICK", "mass": { "chemical_mass": 42193.0, "monoisotopic_mass": 42193.0 }, "refseq": {}, "gene_names": [ { "name": "SLC25A48", "type": "recommended", "evidence": [ { "id": "A0A8V0YHC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHC6" } ] } ], "protein_names": [ { "name": "Solute carrier family 25 member 48", "type": "recommended", "evidence": [ { "id": "A0A8V0YHC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHC6/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Mitochondrial transporter that transports choline across the inner mitochondrial membrane.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHA2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHA2#function" }, { "database": "UniProtKB", "id": "ARBA00094232", "url": "https://www.uniprot.org/uniprotkb/ARBA00094232#function" }, { "database": "UniProtKB", "id": "A0A8V0YHA6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHA6#function" }, { "database": "UniProtKB", "id": "A0A8V0YHC6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHC6#function" }, { "database": "UniProtKB", "id": "A0A8V0YK72", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK72#function" }, { "database": "UniProtKB", "id": "A0A8V0YK94", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK94#function" }, { "database": "UniProtKB", "id": "A0A8V0YQ46", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ46#function" }, { "database": "UniProtKB", "id": "A0A8V0YBT3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBT3#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHC6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHC6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SLC25A48", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHC6", "locus": { "chromosome": "13", "start_pos": 14853928, "end_pos": 14948838, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013042", "url": "https://www.ensembl.org/id/ENSGALG00010013042" } ] } } ], "crossref": [ { "id": "A0A8V0YHC6", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YHC6", "database": "AlphaFoldDB", "categories": [] }, { "id": "416308", "url": "https://www.ncbi.nlm.nih.gov/gene/416308", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002067", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002067", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018108", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018108", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023395", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023395", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050567", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050567", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:416308", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416308", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YBT3", "url": "https://www.orthodb.org/?gene=A0A8V0YBT3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YBT8", "url": "https://www.orthodb.org/?gene=A0A8V0YBT8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YHA2", "url": "https://www.orthodb.org/?gene=A0A8V0YHA2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YHA6", "url": "https://www.orthodb.org/?gene=A0A8V0YHA6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YHC6", "url": "https://www.orthodb.org/?gene=A0A8V0YHC6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YK72", "url": "https://www.orthodb.org/?gene=A0A8V0YK72", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YK94", "url": "https://www.orthodb.org/?gene=A0A8V0YK94", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YQ46", "url": "https://www.orthodb.org/?gene=A0A8V0YQ46", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45624", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45624", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45624:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45624:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00153", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00153", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "32751", "url": "https://www.rhea-db.org/rhea/32751", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YBT3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBT3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YBT3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBT3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YBT8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBT8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YBT8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBT8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHA2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHA2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHA2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHA2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHA6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHA6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHA6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHA6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHC6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHC6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHC6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHC6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YK72", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK72", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YK72-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK72-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YK94", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK94", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YK94-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK94-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQ46", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ46", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQ46-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ46-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLRCICSQTKAERFFKPPVLCTAENAPWQTRWDSCTSNLALFSRCQTEDLKENYLIQHQVGCPLQAGEKRIPFHPPEHEGMFEGRTRMCFPPGDGGAASVVVGHPLDTVKTRLQAGQGYGNTLNCILTVYRNESVAGFFKGMSFPLASIAVYSSVVFGVFSNTQRLLGQLRHGDASHAPALVDVALASTVAGFISVGIGTPVDLVKIRLQMQTQTYSTANVKLKPTVPGFPVYQGPIHCFRTVLQKEGIAGIYRGMGAMLLRDVPGYCLYFIPYTFFCGWITPDGSISPNPASIWLAGGVAGAISWGTATPMDVVKSRLQADGVYLNKYKGILDCILQSYQNEGLKVFFRGITINAVRGFPTSSAMFLGYELSLKAMKRDQTETNP", "length": 386, "header": "tr|A0A8V0YHC6-1|A0A8V0YHC6_CHICK Isoform 1 of Solute carrier family 25 member 48 OS=Gallus gallus OX=9031 GN=SLC25A48 PE=3 SV=1 CANONICAL=A0A8V0YHC6-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YBT3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHC6/entry#A0A8V0YBT3-1", "sequence": { "sequence": "MGSLQLQDFAAGWVGGAASVVVGHPLDTVKTRLQAGQGYGNTLNCILTVYRNESVAGFFKGMSFPLASIAVYSSVVFGVFSNTQRLLGQLRHGDASHAPALVDVALASTVAGFISVGIGTPVDLVKIRLQMQTQTYSTANVKLKPTVPGFPVYQGPIHCFRTVLQKEGIAGIYRGMGAMLLRDVPGYCLYFIPYTFFCGWITPDGSISPNPASIWLAGGVAGAISWGTATPMDVVKSRLQADGVYLNKYKGILDCILQSYQNEGLKVFFRGITINAVRGFPTSSAMFLGYELSLKAMKRDQTETNP", "length": 306, "header": "tr|A0A8V0YBT3-1|A0A8V0YBT3_CHICK Computationally mapped isoform of Solute carrier family 25 member 48 OS=Gallus gallus OX=9031 GN=SLC25A48 PE=3 SV=1 CANONICAL=A0A8V0YHC6-1" }, "locus": { "chromosome": "13", "start_pos": 14870898, "end_pos": 14861688, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031271.1", "url": "https://www.ensembl.org/id/ENSGALT00010031271.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018224.1", "url": "https://www.ensembl.org/id/ENSGALP00010018224.1" } ] } }, { "isoform_ac": "A0A8V0YBT8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHC6/entry#A0A8V0YBT8-1", "sequence": { "sequence": "MLLATVQAGLGVFVCNFFSVVALLCCGSVGGLALCCNTLPSLDAQAAEELPVWLWAIPWTPSRLVCKPDRDMEIHSTAFLLCTEMSRNTQRLLGQLRHGDASHAPALVDVALASTVAGFISVGIGTPVDLVKIRLQMQTQTYSTANVKLKPTVPGFPVYQGPIHCFRTVLQKEGIAGIYRGMGAMLLRDVPGYCLYFIPYTFFCGWITPDGSISPNPASIWLAGGVAGAISWGTATPMDVVKSRLQADGVYLNKYKGILDCILQSYQNEGLKVFFRGITINAVRGFPTSSAMFLGYELSLKAMKRDQTETNP", "length": 312, "header": "tr|A0A8V0YBT8-1|A0A8V0YBT8_CHICK Computationally mapped isoform of Solute carrier family 25 member 48 OS=Gallus gallus OX=9031 GN=SLC25A48 PE=3 SV=1 CANONICAL=A0A8V0YHC6-1" }, "locus": { "chromosome": "13", "start_pos": 14877028, "end_pos": 14861688, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031279.1", "url": "https://www.ensembl.org/id/ENSGALT00010031279.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018230.1", "url": "https://www.ensembl.org/id/ENSGALP00010018230.1" } ] } }, { "isoform_ac": "A0A8V0YHA2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHC6/entry#A0A8V0YHA2-1", "sequence": { "sequence": "MGVDLNVDLCSAGAASVVVGHPLDTVKTRLQAGQGYGNTLNCILTVYRNESVAGFFKGMSFPLASIAVYSSVVFGVFSNTQRLLGQLRHGDASHAPALVDVALASTVAGFISVGIGTPVDLVKIRLQMQTQTYSTANVKLKPTVPGFPVYQGPIHCFRTVLQKEGIAGIYRGMGAMLLRDVPGYCLYFIPYTFFCGWITPDGSISPNPASIWLAGGVAGAISWGTATPMDVVKSRLQADGVYLNKYKGILDCILQSYQNEGLKVFFRGITINAVRGFPTSSAMFLGYELSLKAMKRDQTETNP", "length": 303, "header": "tr|A0A8V0YHA2-1|A0A8V0YHC6_CHICK Computationally mapped isoform of Solute carrier family 25 member 48 OS=Gallus gallus OX=9031 GN=SLC25A48 PE=3 SV=1 CANONICAL=A0A8V0YHC6-1" }, "locus": { "chromosome": "13", "start_pos": 14874952, "end_pos": 14861688, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031296.1", "url": "https://www.ensembl.org/id/ENSGALT00010031296.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018244.1", "url": "https://www.ensembl.org/id/ENSGALP00010018244.1" } ] } }, { "isoform_ac": "A0A8V0YHA6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHC6/entry#A0A8V0YHA6-1", "sequence": { "sequence": "MRGCLKVEPECAFLLGMETRLQAGQGYGNTLNCILTVYRNESVAGFFKGMSFPLASIAVYSSVVFGVFSNTQRLLGQLRHGDASHAPALVDVALASTVAGFISVGIGTPVDLVKIRLQMQTQTYSTANVKLKPTVPGFPVYQGPIHCFRTVLQKEGIAGIYRGMGAMLLRDVPGYCLYFIPYTFFCGWITPDGSISPNPASIWLAGGVAGAISWGTATPMDVVKSRLQADGVYLNKYKGILDCILQSYQNEGLKVFFRGITINAVRGFPTSSAMFLGYELSLKAMKRDQTETNP", "length": 294, "header": "tr|A0A8V0YHA6-1|A0A8V0YHA6_CHICK Computationally mapped isoform of Solute carrier family 25 member 48 OS=Gallus gallus OX=9031 GN=SLC25A48 PE=3 SV=1 CANONICAL=A0A8V0YHC6-1" }, "locus": { "chromosome": "13", "start_pos": 14893309, "end_pos": 14861688, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031304.1", "url": "https://www.ensembl.org/id/ENSGALT00010031304.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018249.1", "url": "https://www.ensembl.org/id/ENSGALP00010018249.1" } ] } }, { "isoform_ac": "A0A8V0YHC6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHC6/entry#A0A8V0YHC6-1", "sequence": { "sequence": "MLRCICSQTKAERFFKPPVLCTAENAPWQTRWDSCTSNLALFSRCQTEDLKENYLIQHQVGCPLQAGEKRIPFHPPEHEGMFEGRTRMCFPPGDGGAASVVVGHPLDTVKTRLQAGQGYGNTLNCILTVYRNESVAGFFKGMSFPLASIAVYSSVVFGVFSNTQRLLGQLRHGDASHAPALVDVALASTVAGFISVGIGTPVDLVKIRLQMQTQTYSTANVKLKPTVPGFPVYQGPIHCFRTVLQKEGIAGIYRGMGAMLLRDVPGYCLYFIPYTFFCGWITPDGSISPNPASIWLAGGVAGAISWGTATPMDVVKSRLQADGVYLNKYKGILDCILQSYQNEGLKVFFRGITINAVRGFPTSSAMFLGYELSLKAMKRDQTETNP", "length": 386, "header": "tr|A0A8V0YHC6-1|A0A8V0YHC6_CHICK Isoform 1 of Solute carrier family 25 member 48 OS=Gallus gallus OX=9031 GN=SLC25A48 PE=3 SV=1 CANONICAL=A0A8V0YHC6-1" }, "locus": { "chromosome": "13", "start_pos": 14937140, "end_pos": 14861688, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031335.1", "url": "https://www.ensembl.org/id/ENSGALT00010031335.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018274.1", "url": "https://www.ensembl.org/id/ENSGALP00010018274.1" } ] } }, { "isoform_ac": "A0A8V0YK72-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHC6/entry#A0A8V0YK72-1", "sequence": { "sequence": "MWISVVQTRLQAGQGYGNTLNCILTVYRNESVAGFFKGMSFPLASIAVYSSVVFGVFSNTQRLLGQLRHGDASHAPALVDVALASTVAGFISVGIGTPVDLVKIRLQMQTQTYSTANVKLKPTVPGFPVYQGPIHCFRTVLQKEGIAGIYRGMGAMLLRDVPGYCLYFIPYTFFCGWITPDGSISPNPASIWLAGGVAGAISWGTATPMDVVKSRLQADGVYLNKYKGILDCILQSYQNEGLKVFFRGITINAVRGFPTSSAMFLGYELSLKAMKRDQTETNP", "length": 283, "header": "tr|A0A8V0YK72-1|A0A8V0YK72_CHICK Computationally mapped isoform of Solute carrier family 25 member 48 OS=Gallus gallus OX=9031 GN=SLC25A48 PE=3 SV=1 CANONICAL=A0A8V0YHC6-1" }, "locus": { "chromosome": "13", "start_pos": 14874936, "end_pos": 14861688, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031284.1", "url": "https://www.ensembl.org/id/ENSGALT00010031284.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018233.1", "url": "https://www.ensembl.org/id/ENSGALP00010018233.1" } ] } }, { "isoform_ac": "A0A8V0YK94-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHC6/entry#A0A8V0YK94-1", "sequence": { "sequence": "MFEGRTRMCFPPGDGGAASVVVGHPLDTVKTRLQAGQGYGNTLNCILTVYRNESVAGFFKGMSFPLASIAVYSSVVFGVFSNTQRLLGQLRHGDASHAPALVDVALASTVAGFISVGIGTPVDLVKIRLQMQTQTYSTANVKLKPTVPGFPVYQGPIHCFRTVLQKEGIAGIYRGMGAMLLRDVPGYCLYFIPYTFFCGWITPDGSISPNPASIWLAGGVAGAISWGTATPMDVVKSRLQADGVYLNKYKGILDCILQSYQNEGLKVFFRGITINAVRGFPTSSAMFLGYELSLKAMKRDQTETNP", "length": 306, "header": "tr|A0A8V0YK94-1|A0A8V0YK94_CHICK Computationally mapped isoform of Solute carrier family 25 member 48 OS=Gallus gallus OX=9031 GN=SLC25A48 PE=3 SV=1 CANONICAL=A0A8V0YHC6-1" }, "locus": { "chromosome": "13", "start_pos": 14893301, "end_pos": 14861688, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031316.1", "url": "https://www.ensembl.org/id/ENSGALT00010031316.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018258.1", "url": "https://www.ensembl.org/id/ENSGALP00010018258.1" } ] } }, { "isoform_ac": "A0A8V0YQ46-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHC6/entry#A0A8V0YQ46-1", "sequence": { "sequence": "MRGCLKVEPECAFLLGMEIHPGVERQKKAVATFQFPLARGFSDEPGHPREEGAASVVVGHPLDTVKTRLQAGQGYGNTLNCILTVYRNESVAGFFKGMSFPLASIAVYSSVVFGVFSNTQRLLGQLRHGDASHAPALVDVALASTVAGFISVGIGTPVDLVKIRLQMQTQTYSTANVKLKPTVPGFPVYQGPIHCFRTVLQKEGIAGIYRGMGAMLLRDVPGYCLYFIPYTFFCGWITPDGSISPNPASIWLAGGVAGAISWGTATPMDVVKSRLQADGVYLNKYKGILDCILQSYQNEGLKVFFRGITINAVRGFPTSSAMFLGYELSLKAMKRDQTETNP", "length": 342, "header": "tr|A0A8V0YQ46-1|A0A8V0YQ46_CHICK Computationally mapped isoform of Solute carrier family 25 member 48 OS=Gallus gallus OX=9031 GN=SLC25A48 PE=3 SV=1 CANONICAL=A0A8V0YHC6-1" }, "locus": { "chromosome": "13", "start_pos": 14893309, "end_pos": 14861688, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031325.1", "url": "https://www.ensembl.org/id/ENSGALT00010031325.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018266.1", "url": "https://www.ensembl.org/id/ENSGALP00010018266.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:416308", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416308", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHC6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHC6" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHC6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHC6" } ], "pmid": "" }, { "name": "mitochondrial membrane", "id": "GO:0031966", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031966", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHC6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHC6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "transmembrane transporter activity", "id": "GO:0022857", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022857", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHC6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHC6" } ], "pmid": "" }, { "name": "choline transmembrane transporter activity", "id": "GO:0015220", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015220", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHC6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHC6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "transmembrane transport", "id": "GO:0055085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055085", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHC6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHC6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 132, "end_pos": 134, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "32751", "name": "", "equation": "choline(out) = choline(in)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "32751", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/32751" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 132, "end_pos": 134 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YHA8-1", "uniprot_ac": "A0A8V0YHA8", "uniprot_id": "A0A8V0YHA8_CHICK", "mass": { "chemical_mass": 212577.0, "monoisotopic_mass": 212577.0 }, "refseq": {}, "gene_names": [ { "name": "MAP2", "type": "recommended", "evidence": [ { "id": "A0A8V0YHA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHA8" } ] } ], "protein_names": [ { "name": "Microtubule-associated protein", "type": "recommended", "evidence": [ { "id": "A0A8V0YHA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHA8/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHA8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHA8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MAP2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHA8", "locus": { "chromosome": "7", "start_pos": 2633123, "end_pos": 2441312, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010011321", "url": "https://www.ensembl.org/id/ENSGALG00010011321" } ] } } ], "crossref": [ { "id": "ENSGALG00000002789", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000002789", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "424001", "url": "https://www.ncbi.nlm.nih.gov/gene/424001", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001084", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001084", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013588", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013588", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018459", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018459", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027324", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027324", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q2U4G6", "url": "https://www.orthodb.org/?gene=A0A3Q2U4G6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y467", "url": "https://www.orthodb.org/?gene=A0A8V0Y467", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y8V9", "url": "https://www.orthodb.org/?gene=A0A8V0Y8V9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y8W5", "url": "https://www.orthodb.org/?gene=A0A8V0Y8W5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YAD7", "url": "https://www.orthodb.org/?gene=A0A8V0YAD7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YHA3", "url": "https://www.orthodb.org/?gene=A0A8V0YHA3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YHA8", "url": "https://www.orthodb.org/?gene=A0A8V0YHA8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YHB3", "url": "https://www.orthodb.org/?gene=A0A8V0YHB3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11501", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11501", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11501:SF15", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11501:SF15", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00418", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00418", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08377", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08377", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF10522", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10522", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A3Q2U4G6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U4G6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2U4G6-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U4G6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y467", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y467", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y467-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y467-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y8V9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y8V9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y8V9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y8V9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y8W5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y8W5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y8W5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y8W5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YAD7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAD7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YAD7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAD7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHA3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHA3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHA3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHA3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHA8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHA8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHA8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHA8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHB3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHB3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHB3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHB3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAEDRKDEAKAPHWTSGQLTEAASHPHSPDIKEQGGAGAGLVRSANGFPYQEGEEPGLGSREQPGTYARSKENGINGELSAGDRETAEEVSARIVQVVTAEAVAVLKGEQEKEAQHKDQPGPLPIAVEESANLPPSPPPSPASEQTGALEEEEEPVESPMAVEVKPAALPGTQLGKEHGPTEPSEQAKGLSKGQPDFGLEATVCREDKIPSVASSRESLTVVGEMPLKDTSPSLAAEATKMEFRVQEGTCPFTTDPLDTKQQESGKDSKTEQPKHDALVPQPTKTEATDKKDLPSKDKEKMPSPLSEQILETDSQKKLEAGFAEPPAKLPISPVQKDLPSELPEGSKAEERTADKPSSSNQVIPMTFKDDLKDVQDLAISHDGSSLLASEPKTEAAKSELPSGPSLALPQGLPLKDSAKTKPEPADQLFAKELAKDEQTHRGMTLSLQEVSAVTVDGLKTPSTQKIPAWGQEKDMTKDETDEEERYDFYDKGEARILDDGKFTTKPEVKTLSQDKADFPKDGETKMSDLFKAEKEMDQSGLQATIATEKDMQPSTEVSPSKLSHVPIPEKTTEHPDTPQLSQITEKSPEAPSSTTDKIPTPEPSQEKDVKKETKEDKESVSATHEVKTEVDRSGMSKYFETSALKEEAFKTGTLKQGSDYYELSDTKESAYDTFQADRLIPEDKEEEEEELQMELDQQQGMPAHEIGYSTLAQSYTPDKSEEPSSPTERMFTIDPKVYGDKRELHSKNKDDLTLSRSLGLGGRSAIEQRSMSINLPMSCLDSIALGFSFGRAHDLSPLASDILTNTSGSMDEGDDYLPATTPAMERAPCFPIDSREEDEHIEEEKAMTEEKVQPETLVESPFPAKDYYKNGAVLAPDLPEMLDLAGTRSRVASVSADAELAQKKSVPSDAVVEDSSTALASVTDENHVTLKAESQLEDLGYCVFNKYTVPLPSPVQDSENLTSETCPFYEGTDEKLRRSLAPDLSLIEVKLAAAEKSKEEFLSEKDLAQQAAGESFLARDFEQEKKEKLDTVLEKSEDQVDSKEGYPIKDSESEKTRPEAILEMKEEGISDKVHVPDDTTYNRILATEVTAERDAVSFLMEKEKTLSVVPELAEVEAPIKPDYNAIKHDMEVAARRADQEYQSQLDSRISDVVSLPSGKDKAPVKKTEPEPKETQQKDQIILSREAKDADLLSKAEPSYVKDSIKLSETEIKEKVTKPDLVHQEAVDKEESYESSGEHDQTQESLNGEPLKQEDVKGEAPKPSASEEEVSTQLPAKEPSTELLLPKAEPPQEEPAEIQMESIPQPPEETEKIPDTVVKPTEVQTLLPSEVTAEATEREEHEEEEVEGGQEEKEEDKHLMSEMPQEMDFGKPTDEELLAKVCPEALPELKGIIESVVTVEDDFITVVQTTVDEGESASHSVRFAATQQEDIEAVDSQAEEELEIEEVVDIQAEPREGSPEAPASPEREEILLTDYKTETCDDYKDETTVDDSIMDTDSLWADTQDDDRSIMTEQLETVPKEEKAERELRRSSLDKHKKEKPFKTGRGRISTPERKIAKKEPSTLSRDEVRRKKAVYKKAELAKKTEVQAHSPSRKIILKPAIKYTRPTHLSCVKRKQTAVGETNQTPGVFKQAKEKLSDGVSKSPEKRSSLPRPSSILPPRRAVSGDRDREENSLSLTTSLSSSVRRTTRSEPIRSRTGKSGTSTPTTPGSTAITPGTPPSYSSRTPGTPGTPSYSRTPHTPGTPKSAILVPTEKKVAIIRTPPKSPATPKQLRVINQPLPDLKNVRSKIGSTDNIKYQPKGGQVQIVTKKIDLSHVTSKCGSLKNIHHKPGGGRVKIESVKLDFKEKAQAKVGSLENAHHVPGGGNVKIDSQKLNFREHAKARVDHGAEIITQSPGRSSVASPRRLSNVSSSGSINLLESPQLATLAEDVTAALAKQGL", "length": 1939, "header": "tr|A0A8V0YHA8-1|A0A8V0YHA8_CHICK Isoform 1 of Microtubule-associated protein OS=Gallus gallus OX=9031 GN=MAP2 PE=4 SV=1 CANONICAL=A0A8V0YHA8-1" }, "isoforms": [ { "isoform_ac": "A0A3Q2U4G6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHA8/entry#A0A3Q2U4G6-1", "sequence": { "sequence": "MAEDRKDEAKAPHWTSGQLTEAASHPHSPDIKEQGGAGAGLVRSANGFPYQEGEEPGLGSREQPGTYARSKENGINGELSAGDRETAEEVSARIVQVVTAEAVAVLKGEQEKEAQHKDQPGPLPIAVEESANLPPSPPPSPASEQTGALEEAAVGETNQTPGVFKQAKEKLSTASLSKIPASKSRAKSLLPPRPSSACSLTTKRATFLDTDSYYVRPSSAGPRDCLPYSISDAKDGVSKSPEKRSSLPRPSSILPPRRAVSGDRDREENSLSLTTSLSSSVRRTTRSEPIRSRTGKSGTSTPTTPGSTAITPGTPPSYSSRTPGTPGTPSYSRTPHTPGTPKSAILVPTEKKVAIIRTPPKSPATPKQLRVINQPLPDLKNVRSKIGSTDNIKYQPKGGQVRILNKKIDFSDIQSRCGSRDNIKHSAGGGNVQIVTKKIDLSHVTSKCGSLKNIHHKPGGGRVKIESVKLDFKEKAQAKVGSLENAHHVPGGGNVKIDSQKLNFREHAKARVDHGAEIITQSPGRSSVASPRRLSNVSSSGSINLLESPQLATLAEDVTAALAKQGL", "length": 567, "header": "tr|A0A3Q2U4G6-1|A0A3Q2U4G6_CHICK Computationally mapped isoform of Microtubule-associated protein OS=Gallus gallus OX=9031 GN=MAP2 PE=4 SV=1 CANONICAL=A0A8V0YHA8-1" }, "locus": { "chromosome": "7", "start_pos": 2629231, "end_pos": 2568889, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027072.1", "url": "https://www.ensembl.org/id/ENSGALT00010027072.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015403.1", "url": "https://www.ensembl.org/id/ENSGALP00010015403.1" } ] } }, { "isoform_ac": "A0A8V0Y467-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHA8/entry#A0A8V0Y467-1", "sequence": { "sequence": "MAEDRKDEAKAPHWTSGQLTEAASHPHSPDIKEQGGAGAGLVRSANGFPYQEGEEPGLGSREQPGTYARSKENGINGELSAGDRETAEEVSARIVQVVTAEAVAVLKGEQEKEAQHKDQPGPLPIAVEESANLPPSPPPSPASEQTGALEEAAVGETNQTPGVFKQAKEKLSDGVSKSPEKRSSLPRPSSILPPRRAVSGDRDREENSLSLTTSLSSSVRRTTRSEPIRSRTGKSGTSTPTTPGSTAITPGTPPSYSSRTPGTPGTPSYSRTPHTPGTPKSAILVPTEKKVAIIRTPPKSPATPKQLRVINQPLPDLKNVRSKIGSTDNIKYQPKGGQVQIVTKKIDLSHVTSKCGSLKNIHHKPGGGRVKIESVKLDFKEKAQAKVGSLENAHHVPGGGNVKIDSQKLNFREHAKARVDHGAEIITQSPGRSSVASPRRLSNVSSSGSKDLCNCNHPSIERILGRCGLR", "length": 470, "header": "tr|A0A8V0Y467-1|A0A8V0Y467_CHICK Computationally mapped isoform of Microtubule-associated protein OS=Gallus gallus OX=9031 GN=MAP2 PE=4 SV=1 CANONICAL=A0A8V0YHA8-1" }, "locus": { "chromosome": "7", "start_pos": 2631978, "end_pos": 2568889, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027088.1", "url": "https://www.ensembl.org/id/ENSGALT00010027088.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015411.1", "url": "https://www.ensembl.org/id/ENSGALP00010015411.1" } ] } }, { "isoform_ac": "A0A8V0Y8V9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHA8/entry#A0A8V0Y8V9-1", "sequence": { "sequence": "MAEDRKDEAKAPHWTSGQLTEAASHPHSPDIKEQGGAGAGLVRSANGFPYQEGEEPGLGSREQPGTYARSKENGINGELSAGDRETAEVSARIVQVVTAEAVAVLKGEQEKEAQHKDQPGPLPIAVEESANLPPSPPPSPASEQTGALEEATKMEFRVQEGTCPFTTDPLDTKQQESGKDSKTEQPKHDALVPQPTKTEATDKKDLPSKDKEKMPSPLSEQILETDSQKKLEAGFAEPPAKLPISPVQKDLPSELPEGSKAEERTADKPSSSNQVIPMTFKDDLKDVQDLAISHDGSSLLASEPKTEAAKSELPSGPSLALPQGLPLKDSAKTKPEPADQLFAKELAKDEQTHRGMTLSLQEVSAVTVDGLKTPSTQKIPAWGQEKDMTKDETDEEERYDFYDKGEARILDDGKFTTKPEVKTLSQDKADFPKDGETKMSDLFKAEKEMDQSGLQATIATEKDMQPSTEVSPSKLSHVPIPEKTTEHPDTPQLSQITEKSPEAPSSTTDKIPTPEPSQEKDVKKETKEDKESVSATHEVKTEVDRSGMSKYFETSALKEEAFKTGTLKQGSDYYELSDTKESAYDTFQADRLIPEDKEEEEEELQMELDQQQGMPAHEIGYSTLAQSYTPDKSEEPSSPTERMFTIDPKVYGDKRELHSKNKDDLTLSRSLGLGGRSAIEQRSMSINLPMSCLDSIALGFSFGRAHDLSPLASDILTNTSGSMDEGDDYLPATTPAMERAPCFPIDSREEDEHIEEEKAMTEEKVQPETLVESPFPAKDYYKNGAVLAPDLPEMLDLAGTRSRVASVSADAELAQKKSVPSDAVVEDSSTALASVTDENHVTLKAESQLEDLGYCVFNKYTVPLPSPVQDSENLTSETCPFYEGTDEKLRRSLAPDLSLIEVKLAAAEKSKEEFLSEKDLAQQAAGESFLARDFEQEKKEKLDTVLEKSEDQVDSKEGYPIKDSESEKTRPEAILEMKEEGISDKVHVPDDTTYNRILATEVTAERDAVSFLMEKEKTLSVVPELAEVEAPIKPDYNAIKHDMEVAARRADQEYQSQLDSRISDVVSLPSGKDKAPVKKTEPEPKETQQKDQIILSREAKDADLLSKAEPSYVKDSIKLSETEIKEKVTKPDLVHQEAVDKEESYESSGEHDQTQESLNGEPLKQEDVKGEAPKPSASEEEVSTQLPAKEPSTELLLPKAEPPQEEPAEIQMESIPQPPEETEKIPDTVVKPTEVQTLLPSEVTAEATEREEHEEEEVEGGQEEKEEDKHLMSEMPQEMDFGKPTDEELLAKVCPEALPELKGIIESVVTVEDDFITVVQTTVDEGESASHSVRFAATQQEDIEAVDSQAEEELEIEEVVDIQAEPREGSPEAPASPEREEILLTDYKTETCDDYKDETTVDDSIMDTDSLWADTQDDDRSIMTEQLETVPKEEKAERELRRSSLDKHKKEKPFKTGRGRISTPERKIAKKEPSTLSRDEVRRKKAVYKKAELAKKTEVQAHSPSRKIILKPAIKYTRPTHLSCVKRKQTAVGETNQTPGVFKQAKEKLSDGVSKSPEKRSSLPRPSSILPPRRAVSGDRDREENSLSLTTSLSSSVRRTTRSEPIRSRTGKSGTSTPTTPGSTAITPGTPPSYSSRTPGTPGTPSYSRTPHTPGTPKSAILVPTEKKVAIIRTPPKSPATPKQLRVINQPLPDLKNVRSKIGSTDNIKYQPKGGQVQIVTKKIDLSHVTSKCGSLKNIHHKPGGGRVKIESVKLDFKEKAQAKVGSLENAHHVPGGGNVKIDSQKLNFREHAKARVDHGAEIITQSPGRSSVASPRRLSNVSSSGSINLLESPQLATLAEDVTAALAKQGL", "length": 1852, "header": "tr|A0A8V0Y8V9-1|A0A8V0Y8V9_CHICK Computationally mapped isoform of Microtubule-associated protein OS=Gallus gallus OX=9031 GN=MAP2 PE=4 SV=1 CANONICAL=A0A8V0YHA8-1" }, "locus": { "chromosome": "7", "start_pos": 2629231, "end_pos": 2568889, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027074.1", "url": "https://www.ensembl.org/id/ENSGALT00010027074.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015405.1", "url": "https://www.ensembl.org/id/ENSGALP00010015405.1" } ] } }, { "isoform_ac": "A0A8V0Y8W5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHA8/entry#A0A8V0Y8W5-1", "sequence": { "sequence": "MAEDRKDEAKAPHWTSGQLTEAASHPHSPDIKEQGGAGAGLVRSANGFPYQEGEEPGLGSREQPGTYARSKENGINGELSAGDRETAEVSARIVQVVTAEAVAVLKGEQEKEAQHKDQPGPLPIAVEESANLPPSPPPSPASEQTGALEEAVGETNQTPGVFKQAKEKLSTASLSKIPASKSRAKSLLPPRPSSACSLTTKRATFLDTDSYYVRPSSAGPRDCLPYSISDAKDGVSKSPEKRSSLPRPSSILPPRRAVSGDRDREENSLSLTTSLSSSVRRTTRSEPIRSRTGKSGTSTPTTPGSTAITPGTPPSYSSRTPGTPGTPSYSRTPHTPGTPKSAILVPTEKKVAIIRTPPKSPATPKQLRVINQPLPDLKNVRSKIGSTDNIKYQPKGGQVQIVTKKIDLSHVTSKCGSLKNIHHKPGGGRVKIESVKLDFKEKAQAKVGSLENAHHVPGGGNVKIDSQKLNFREHAKARVDHGAEIITQSPGRSSVASPRRLSNVSSSGSINLLESPQLATLAEDVTAALAKQGL", "length": 534, "header": "tr|A0A8V0Y8W5-1|A0A8V0Y8W5_CHICK Computationally mapped isoform of Microtubule-associated protein OS=Gallus gallus OX=9031 GN=MAP2 PE=4 SV=1 CANONICAL=A0A8V0YHA8-1" }, "locus": { "chromosome": "7", "start_pos": 2629231, "end_pos": 2568889, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027083.1", "url": "https://www.ensembl.org/id/ENSGALT00010027083.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015410.1", "url": "https://www.ensembl.org/id/ENSGALP00010015410.1" } ] } }, { "isoform_ac": "A0A8V0YAD7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHA8/entry#A0A8V0YAD7-1", "sequence": { "sequence": "MAEDRKDEAKAPHWTSGQLTEAASHPHSPDIKEQGGAGAGLVRSANGFPYQEGEEPGLGSREQPGTYARSKENGINGELSAGDRETAEVSARIVQVVTAEAVAVLKGEQEKEAQHKDQPGPLPIAVEESANLPPSPPPSPASEQTGALEEAVGETNQTPGVFKQAKEKLSDGVSKSPEKRSSLPRPSSILPPRRAVSGDRDREENSLSLTTSLSSSVRRTTRSEPIRSRTGKSGTSTPTTPGSTAITPGTPPSYSSRTPGTPGTPSYSRTPHTPGTPKSAILVPTEKKVAIIRTPPKSPATPKQLRVINQPLPDLKNVRSKIGSTDNIKYQPKGGQVRILNKKIDFSDIQSRCGSRDNIKHSAGGGNVQIVTKKIDLSHVTSKCGSLKNIHHKPGGGRVKIESVKLDFKEKAQAKVGSLENAHHVPGGGNVKIDSQKLNFREHAKARVDHGAEIITQSPGRSSVASPRRLSNVSSSGSINLLESPQLATLAEDVTAALAKQGL", "length": 503, "header": "tr|A0A8V0YAD7-1|A0A8V0YAD7_CHICK Computationally mapped isoform of Microtubule-associated protein OS=Gallus gallus OX=9031 GN=MAP2 PE=4 SV=1 CANONICAL=A0A8V0YHA8-1" }, "locus": { "chromosome": "7", "start_pos": 2629231, "end_pos": 2568889, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027062.1", "url": "https://www.ensembl.org/id/ENSGALT00010027062.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015398.1", "url": "https://www.ensembl.org/id/ENSGALP00010015398.1" } ] } }, { "isoform_ac": "A0A8V0YHA3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHA8/entry#A0A8V0YHA3-1", "sequence": { "sequence": "MFAYFSLSIIHTKMFCTPHDCLPVSALNNFIIKPKQTTSDLIAATKMEFRVQEGTCPFTTDPLDTKQQESGKDSKTEQPKHDALVPQPTKTEATDKKDLPSKDKEKMPSPLSEQILETDSQKKLEAGFAEPPAKLPISPVQKDLPSELPEGSKAEERTADKPSSSNQVIPMTFKDDLKDVQDLAISHDGSSLLASEPKTEAAKSELPSGPSLALPQGLPLKDSAKTKPEPADQLFAKELAKDEQTHRGMTLSLQEVSAVTVDGLKTPSTQKIPAWGQEKDMTKDETDEEERYDFYDKGEARILDDGKFTTKPEVKTLSQDKADFPKDGETKMSDLFKAEKEMDQSGLQATIATEKDMQPSTEVSPSKLSHVPIPEKTTEHPDTPQLSQITEKSPEAPSSTTDKIPTPEPSQEKDVKKETKEDKESVSATHEVKTEVDRSGMSKYFETSALKEEAFKTGTLKQGSDYYELSDTKESAYDTFQADRLIPEDKEEEEEELQMELDQQQGMPAHEIGYSTLAQSYTPDKSEEPSSPTERMFTIDPKVYGDKRELHSKNKDDLTLSRSLGLGGRSAIEQRSMSINLPMSCLDSIALGFSFGRAHDLSPLASDILTNTSGSMDEGDDYLPATTPAMERAPCFPIDSREEDEHIEEEKAMTEEKVQPETLVESPFPAKDYYKNGAVLAPDLPEMLDLAGTRSRVASVSADAELAQKKSVPSDAVVEDSSTALASVTDENHVTLKAESQLEDLGYCVFNKYTVPLPSPVQDSENLTSETCPFYEGTDEKLRRSLAPDLSLIEVKLAAAEKSKEEFLSEKDLAQQAAGESFLARDFEQEKKEKLDTVLEKSEDQVDSKEGYPIKDSESEKTRPEAILEMKEEGISDKVHVPDDTTYNRILATEVTAERDAVSFLMEKEKTLSVVPELAEVEAPIKPDYNAIKHDMEVAARRADQEYQSQLDSRISDVVSLPSGKDKAPVKKTEPEPKETQQKDQIILSREAKDADLLSKAEPSYVKDSIKLSETEIKEKVTKPDLVHQEAVDKEESYESSGEHDQTQESLNGEPLKQEDVKGEAPKPSASEEEVSTQLPAKEPSTELLLPKAEPPQEEPAEIQMESIPQPPEETEKIPDTVVKPTEVQTLLPSEVTAEATEREEHEEEEVEGGQEEKEEDKHLMSEMPQEMDFGKPTDEELLAKVCPEALPELKGIIESVVTVEDDFITVVQTTVDEGESASHSVRFAATQQEDIEAVDSQAEEELEIEEVVDIQAEPREGSPEAPASPEREEILLTDYKTETCDDYKDETTVDDSIMDTDSLWADTQDDDRSIMTEQLETVPKEEKAERELRRSSLDKHKKEKPFKTGRGRISTPERKIAKKEPSTLSRDEVRRKKAVYKKAELAKKTEVQAHSPSRKIILKPAIKYTRPTHLSCVKRKQTAAVGETNQTPGVFKQAKEKLSDGVSKSPEKRSSLPRPSSILPPRRAVSGDRDREENSLSLTTSLSSSVRRTTRSEPIRSRTGKSGTSTPTTPGSTAITPGTPPSYSSRTPGTPGTPSYSRTPHTPGTPKSAILVPTEKKVAIIRTPPKSPATPKQLRVINQPLPDLKNVRSKIGSTDNIKYQPKGGQVQIVTKKIDLSHVTSKCGSLKNIHHKPGGGRVKIESVKLDFKEKAQAKVGSLENAHHVPGGGNVKIDSQKLNFREHAKARVDHGAEIITQSPGRSSVASPRRLSNVSSSGSINLLESPQLATLAEDVTAALAKQGL", "length": 1746, "header": "tr|A0A8V0YHA3-1|A0A8V0YHA8_CHICK Computationally mapped isoform of Microtubule-associated protein OS=Gallus gallus OX=9031 GN=MAP2 PE=4 SV=1 CANONICAL=A0A8V0YHA8-1" }, "locus": { "chromosome": "7", "start_pos": 2629231, "end_pos": 2599970, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027057.1", "url": "https://www.ensembl.org/id/ENSGALT00010027057.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015397.1", "url": "https://www.ensembl.org/id/ENSGALP00010015397.1" } ] } }, { "isoform_ac": "A0A8V0YHA8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHA8/entry#A0A8V0YHA8-1", "sequence": { "sequence": "MAEDRKDEAKAPHWTSGQLTEAASHPHSPDIKEQGGAGAGLVRSANGFPYQEGEEPGLGSREQPGTYARSKENGINGELSAGDRETAEEVSARIVQVVTAEAVAVLKGEQEKEAQHKDQPGPLPIAVEESANLPPSPPPSPASEQTGALEEEEEPVESPMAVEVKPAALPGTQLGKEHGPTEPSEQAKGLSKGQPDFGLEATVCREDKIPSVASSRESLTVVGEMPLKDTSPSLAAEATKMEFRVQEGTCPFTTDPLDTKQQESGKDSKTEQPKHDALVPQPTKTEATDKKDLPSKDKEKMPSPLSEQILETDSQKKLEAGFAEPPAKLPISPVQKDLPSELPEGSKAEERTADKPSSSNQVIPMTFKDDLKDVQDLAISHDGSSLLASEPKTEAAKSELPSGPSLALPQGLPLKDSAKTKPEPADQLFAKELAKDEQTHRGMTLSLQEVSAVTVDGLKTPSTQKIPAWGQEKDMTKDETDEEERYDFYDKGEARILDDGKFTTKPEVKTLSQDKADFPKDGETKMSDLFKAEKEMDQSGLQATIATEKDMQPSTEVSPSKLSHVPIPEKTTEHPDTPQLSQITEKSPEAPSSTTDKIPTPEPSQEKDVKKETKEDKESVSATHEVKTEVDRSGMSKYFETSALKEEAFKTGTLKQGSDYYELSDTKESAYDTFQADRLIPEDKEEEEEELQMELDQQQGMPAHEIGYSTLAQSYTPDKSEEPSSPTERMFTIDPKVYGDKRELHSKNKDDLTLSRSLGLGGRSAIEQRSMSINLPMSCLDSIALGFSFGRAHDLSPLASDILTNTSGSMDEGDDYLPATTPAMERAPCFPIDSREEDEHIEEEKAMTEEKVQPETLVESPFPAKDYYKNGAVLAPDLPEMLDLAGTRSRVASVSADAELAQKKSVPSDAVVEDSSTALASVTDENHVTLKAESQLEDLGYCVFNKYTVPLPSPVQDSENLTSETCPFYEGTDEKLRRSLAPDLSLIEVKLAAAEKSKEEFLSEKDLAQQAAGESFLARDFEQEKKEKLDTVLEKSEDQVDSKEGYPIKDSESEKTRPEAILEMKEEGISDKVHVPDDTTYNRILATEVTAERDAVSFLMEKEKTLSVVPELAEVEAPIKPDYNAIKHDMEVAARRADQEYQSQLDSRISDVVSLPSGKDKAPVKKTEPEPKETQQKDQIILSREAKDADLLSKAEPSYVKDSIKLSETEIKEKVTKPDLVHQEAVDKEESYESSGEHDQTQESLNGEPLKQEDVKGEAPKPSASEEEVSTQLPAKEPSTELLLPKAEPPQEEPAEIQMESIPQPPEETEKIPDTVVKPTEVQTLLPSEVTAEATEREEHEEEEVEGGQEEKEEDKHLMSEMPQEMDFGKPTDEELLAKVCPEALPELKGIIESVVTVEDDFITVVQTTVDEGESASHSVRFAATQQEDIEAVDSQAEEELEIEEVVDIQAEPREGSPEAPASPEREEILLTDYKTETCDDYKDETTVDDSIMDTDSLWADTQDDDRSIMTEQLETVPKEEKAERELRRSSLDKHKKEKPFKTGRGRISTPERKIAKKEPSTLSRDEVRRKKAVYKKAELAKKTEVQAHSPSRKIILKPAIKYTRPTHLSCVKRKQTAVGETNQTPGVFKQAKEKLSDGVSKSPEKRSSLPRPSSILPPRRAVSGDRDREENSLSLTTSLSSSVRRTTRSEPIRSRTGKSGTSTPTTPGSTAITPGTPPSYSSRTPGTPGTPSYSRTPHTPGTPKSAILVPTEKKVAIIRTPPKSPATPKQLRVINQPLPDLKNVRSKIGSTDNIKYQPKGGQVQIVTKKIDLSHVTSKCGSLKNIHHKPGGGRVKIESVKLDFKEKAQAKVGSLENAHHVPGGGNVKIDSQKLNFREHAKARVDHGAEIITQSPGRSSVASPRRLSNVSSSGSINLLESPQLATLAEDVTAALAKQGL", "length": 1939, "header": "tr|A0A8V0YHA8-1|A0A8V0YHA8_CHICK Isoform 1 of Microtubule-associated protein OS=Gallus gallus OX=9031 GN=MAP2 PE=4 SV=1 CANONICAL=A0A8V0YHA8-1" }, "locus": { "chromosome": "7", "start_pos": 2629231, "end_pos": 2568889, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027067.1", "url": "https://www.ensembl.org/id/ENSGALT00010027067.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015402.1", "url": "https://www.ensembl.org/id/ENSGALP00010015402.1" } ] } }, { "isoform_ac": "A0A8V0YHB3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHA8/entry#A0A8V0YHB3-1", "sequence": { "sequence": "MAEDRKDEAKAPHWTSGQLTEAASHPHSPDIKEQGGAGAGLVRSANGFPYQEGEEPGLGSREQPGTYARSKENGINGELSAGDRETAAVGETNQTPGVFKQAKEKLSTASLSKIPASKSRAKSLLPPRPSSACSLTTKRATFLDTDSYYVRPSSAGPRDCLPYSISDAKDGVSKSPEKRSSLPRPSSILPPRRAVSGDRDREENSLSLTTSLSSSVRRTTRSEPIRSRTGKSGTSTPTTPGSTAITPGTPPSYSSRTPGTPGTPSYSRTPHTPGTPKSAILVPTEKKVAIIRTPPKSPATPKQLRVINQPLPDLKNVRSKIGSTDNIKYQPKGGQVRILNKKIDFSDIQSRCGSRDNIKHSAGGGNVQIVTKKIDLSHVTSKCGSLKNIHHKPGGGRVKIESVKLDFKEKAQAKVGSLENAHHVPGGGNVKIDSQKLNFREHAKARVDHGAEIITQSPGRSSVASPRRLSNVSSSGSINLLESPQLATLAEDVTAALAKQGL", "length": 502, "header": "tr|A0A8V0YHB3-1|A0A8V0YHB3_CHICK Computationally mapped isoform of Microtubule-associated protein OS=Gallus gallus OX=9031 GN=MAP2 PE=4 SV=1 CANONICAL=A0A8V0YHA8-1" }, "locus": { "chromosome": "7", "start_pos": 2629231, "end_pos": 2568889, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027076.1", "url": "https://www.ensembl.org/id/ENSGALT00010027076.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015407.1", "url": "https://www.ensembl.org/id/ENSGALP00010015407.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1714, "start_aa": "Thr", "end_pos": 1714, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1714", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1731, "start_aa": "Thr", "end_pos": 1731, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1731", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "microtubule", "id": "GO:0005874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005874", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHA8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHA8" } ], "pmid": "" }, { "name": "neuron projection", "id": "GO:0043005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043005", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHA8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHA8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "microtubule binding", "id": "GO:0008017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008017", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHA8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHA8" } ], "pmid": "" }, { "name": "dystroglycan binding", "id": "GO:0002162", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002162", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHA8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHA8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "neuron projection development", "id": "GO:0031175", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031175", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHA8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHA8" } ], "pmid": "" }, { "name": "dendrite morphogenesis", "id": "GO:0048813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048813", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHA8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHA8" } ], "pmid": "" }, { "name": "microtubule cytoskeleton organization", "id": "GO:0000226", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000226", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHA8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHA8" } ], "pmid": "" }, { "name": "central nervous system neuron development", "id": "GO:0021954", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021954", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHA8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHA8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1623, "end_pos": 1625, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1908, "end_pos": 1910, "annotation": "n_glycosylation_sequon" }, { "start_pos": 805, "end_pos": 807, "annotation": "n_glycosylation_sequon" }, { "start_pos": 960, "end_pos": 962, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], 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"Ensembl Peptide", "id": "ENSGALP00010018256.1", "url": "https://www.ensembl.org/id/ENSGALP00010018256.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 40, "end_pos": 42, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 40, "end_pos": 42 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", 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{ "uniprot_canonical_ac": "A0A8V0YHB8-1", "uniprot_ac": "A0A8V0YHB8", "uniprot_id": "A0A8V0YHB8_CHICK", "mass": { "chemical_mass": 18999.0, "monoisotopic_mass": 18999.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "RNase H type-1 domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A8V0YHB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHB8/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHB8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHB8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHB8", "locus": {} } ], "crossref": [ { "id": "A0A8V0YHB8", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YHB8", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR002156", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002156", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012337", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012337", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036397", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036397", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR41694", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR41694", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR41694:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR41694:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00075", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00075", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YHB8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHB8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHB8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHB8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVLTSHTVSTVLEVKGGCWLSPQRLLQYQAILVEQDDMEIVVTNIVNPASFLSRTSGEPVTHDCLETIEAVCSSRPDLKEEPLENAKDSWYTDGSSYVHQGVRRAGYTVTTDNKVIESGALTPNTSAQKAEIIVLTRALELAEGRRINIWTDSKYAFGVVHAHGAIWKERGL", "length": 172, "header": "tr|A0A8V0YHB8-1|A0A8V0YHB8_CHICK Isoform 1 of RNase H type-1 domain-containing protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0YHB8-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YHB8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHB8/entry#A0A8V0YHB8-1", "sequence": { "sequence": "MVLTSHTVSTVLEVKGGCWLSPQRLLQYQAILVEQDDMEIVVTNIVNPASFLSRTSGEPVTHDCLETIEAVCSSRPDLKEEPLENAKDSWYTDGSSYVHQGVRRAGYTVTTDNKVIESGALTPNTSAQKAEIIVLTRALELAEGRRINIWTDSKYAFGVVHAHGAIWKERGL", "length": 172, "header": "tr|A0A8V0YHB8-1|A0A8V0YHB8_CHICK Isoform 1 of RNase H type-1 domain-containing protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0YHB8-1" }, "locus": { "chromosome": "W", "start_pos": 4833716, "end_pos": 4830748, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029538.1", "url": "https://www.ensembl.org/id/ENSGALT00010029538.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017170.1", "url": "https://www.ensembl.org/id/ENSGALP00010017170.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "RNA-directed DNA polymerase activity", "id": "GO:0003964", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003964", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHB8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHB8" } ], "pmid": "" }, { "name": "nucleic acid binding", "id": "GO:0003676", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003676", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHB8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHB8" } ], "pmid": "" }, { "name": "RNA-DNA hybrid ribonuclease activity", "id": "GO:0004523", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004523", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHB8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHB8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 124, "end_pos": 126, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YHB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHB8" }, { "id": "PS50879", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50879" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RNase H type-1", "eco_id": "ECO_0000259", "start_pos": 84, "end_pos": 172, "start_aa": "Glu", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 124, "end_pos": 126 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YHC2-1", "uniprot_ac": "A0A8V0YHC2", "uniprot_id": "A0A8V0YHC2_CHICK", "mass": { "chemical_mass": 96123.0, "monoisotopic_mass": 96123.0 }, "refseq": { "ac": "XP_001233408", "name": "WD repeat-containing protein 75 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001233408" }, "gene_names": [ { "name": "WDR75", "type": "recommended", "evidence": [ { "id": "A0A8V0YHC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHC2" } ] }, { "name": "WDR75", "type": "synonym", "evidence": [ { "id": "XP_001233408", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001233408" } ] } ], "protein_names": [ { "name": "WD repeat domain 75", "type": "synonym", "evidence": [ { "id": "A0A8V0YHC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHC2/entry#names_and_taxonomy" } ] }, { "name": "WD repeat-containing protein 75 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_001233408", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001233408" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052538.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_001233408.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_001233408", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001233408" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHC2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHC2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "WDR75", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHC2", "locus": { "chromosome": "7", "start_pos": 480361, "end_pos": 498425, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013048", "url": "https://www.ensembl.org/id/ENSGALG00010013048" } ] } } ], "crossref": [ { "id": "A0A8V0YHC2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YHC2", "database": "AlphaFoldDB", "categories": [] }, { "id": "423985", "url": "https://www.ncbi.nlm.nih.gov/gene/423985", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001680", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001680", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019775", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019775", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036322", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036322", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR053826", "url": "https://www.ebi.ac.uk/interpro/entry/IPR053826", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057644", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057644", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:423985", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423985", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WILNTRI", "url": "https://omabrowser.org/oma/group/WILNTRI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YBW3", "url": "https://www.orthodb.org/?gene=A0A8V0YBW3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YHC2", "url": "https://www.orthodb.org/?gene=A0A8V0YHC2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YK84", "url": "https://www.orthodb.org/?gene=A0A8V0YK84", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YQ22", "url": "https://www.orthodb.org/?gene=A0A8V0YQ22", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR44215", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR44215", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR44215:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR44215:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF23769", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23769", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23869", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23869", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-6791226", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6791226", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_001233408", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001233408", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YBW3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBW3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YBW3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBW3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHC2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHC2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHC2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHC2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YK84", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK84", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YK84-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK84-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQ22", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ22", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQ22-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ22-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPCVQRAELRGGRAAVRFRSRKMVAPAALRVVRCGGRAMHGARAVFSVGARFLLCASGDFVKMYSVATEELVQLLRGHSDLVTGVQLAPHNRLQLYSSSLDGTIKLWDFTDGILIKTFTVGYQLLALYALPSSEDSVFVIIPKSGERDTFQLVSVKLTKAAGQDMEAKELSVVLEGVDASPKCTAFGREGEYVASVKDVNLQVYFFKQKQLNRFSLRATNKKGGNNVFTCVACHPQEDCIATGHADGKIRLWRNFNHKKEYTFSTLHWHHDKVLDLAFSLEGTSLLSGGVESVLVQWHCGSDCKRDFLPRLGSAIEYVSISSDGTFYCTSHTDNRITIINSNLRFSKTIQGLIKARDVKTGLVVDPRTKALVLNGEPGHLQFYCLQSDKQLYSLDIVQQEYIHQAGLNQSDLVRVAFSAQGKWLATVEEREETDLELQLKLWFFDEETQSFKLNTRISMPHEDHITAMCFRDTDEMEDDSLMLVTTGRDCVFKVWVILEDTDPEAQQSLSWSCDFVGSYHSYQATNCCFSEDGSLLAVSFEETVTVWDSSTWDLKCTFCHPPGKIRSICFGRLTCSKYLIGATDHGFLCCWNLLSCALEWSAHLNVVVLQPDPLSEHIAAVSWLFKESSLFVFKPNEARPICIQRKFCKERIQFAAFVPRDVPETIGSEKYLWLRRSQLFFLTDTQELMTVSTKSAQERLTLSSKQLAVEESLPVTPFSLLLGKHRHQQSQGDVDLGKIVHHHHEQDSPAVKELLHTPAHVLPSASFLCPIFINSLLVSKENKSTEETPDEVEMESEEAEDDSDEENSVTEMKQEDKMPLESLGETTHRLSKSEEKELRKIRKVDYSWISVF", "length": 852, "header": "tr|A0A8V0YHC2-1|A0A8V0YHC2_CHICK Isoform 1 of WD repeat domain 75 OS=Gallus gallus OX=9031 GN=WDR75 PE=1 SV=1 CANONICAL=A0A8V0YHC2-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YBW3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHC2/entry#A0A8V0YBW3-1", "sequence": { "sequence": "MHGARAVFSVGARFLLCASGDFVKMYSVATEELVQLLRGHSDLVTGVQLAPHNRLQTFTVGYQLLALYALPSSEDSVFVIIPKSGERDTFQLVSVKLTKAAGQDMEAKELSVVLEGVDASPKCTAFGREGEYVASVKDVNLQVYFFKQKQLNRFSLRATNKKGGNNVFTCVACHPQEDCIATGHADGKIRLWRNFNHKKEYTFSTLHWHHDKVLDLAFSLEGTSLLSGGVESVLVQWHCGSDCKRDFLPRLGSAIEYVSISSDGTFYCTSHTDNRITIINSNLRFSKTIQGLIKARDVKTGLVVDPRTKALVLNGEPGHLQFYCLQSDKQLYSLDIVQQEYIHQAGLNQSDLVRVAFSAQGKWLATVEEREETDLELQLKLWFFDEETQSFKLNTRISMPHEDHITAMCFRDTDEMEDDSLMLVTTGRDCVFKVWVILEDTDPEAQQSLSWSCDFVGSYHSYQATNCCFSEDGSLLAVSFEETVTVWDSSTWDLKCTFCHPPGKIRSICFGRLTCSKYLIGATDHGFLCCWNLLSCALEWSAHLNVVVLQPDPLSEHIAAVSWLFKESSLFVFKPNEARPICIQRKFCKERIQFAAFVPRDVPETIGSEKYLWLRRSQLFFLTDTQELMTVSTKSAQERLTLSSKQLAVEESLPVTPFSLLLGKHRHQQSQGDVDLGKIVHHHHEQDSPAVKELLHTPAHVLPSASFLCPIFINSLLVSKENKSTEETPDEVEMESEEAEDDSDEENSVTEMKQEDKMPLESLGETTHRLSKSEEKELRKIRKVDYSWISVF", "length": 792, "header": "tr|A0A8V0YBW3-1|A0A8V0YBW3_CHICK Computationally mapped isoform of WD repeat domain 75 OS=Gallus gallus OX=9031 GN=WDR75 PE=1 SV=1 CANONICAL=A0A8V0YHC2-1" }, "locus": { "chromosome": "7", "start_pos": 498112, "end_pos": 481452, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031318.1", "url": "https://www.ensembl.org/id/ENSGALT00010031318.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018260.1", "url": "https://www.ensembl.org/id/ENSGALP00010018260.1" } ] } }, { "isoform_ac": "A0A8V0YHC2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHC2/entry#A0A8V0YHC2-1", "sequence": { "sequence": "MPCVQRAELRGGRAAVRFRSRKMVAPAALRVVRCGGRAMHGARAVFSVGARFLLCASGDFVKMYSVATEELVQLLRGHSDLVTGVQLAPHNRLQLYSSSLDGTIKLWDFTDGILIKTFTVGYQLLALYALPSSEDSVFVIIPKSGERDTFQLVSVKLTKAAGQDMEAKELSVVLEGVDASPKCTAFGREGEYVASVKDVNLQVYFFKQKQLNRFSLRATNKKGGNNVFTCVACHPQEDCIATGHADGKIRLWRNFNHKKEYTFSTLHWHHDKVLDLAFSLEGTSLLSGGVESVLVQWHCGSDCKRDFLPRLGSAIEYVSISSDGTFYCTSHTDNRITIINSNLRFSKTIQGLIKARDVKTGLVVDPRTKALVLNGEPGHLQFYCLQSDKQLYSLDIVQQEYIHQAGLNQSDLVRVAFSAQGKWLATVEEREETDLELQLKLWFFDEETQSFKLNTRISMPHEDHITAMCFRDTDEMEDDSLMLVTTGRDCVFKVWVILEDTDPEAQQSLSWSCDFVGSYHSYQATNCCFSEDGSLLAVSFEETVTVWDSSTWDLKCTFCHPPGKIRSICFGRLTCSKYLIGATDHGFLCCWNLLSCALEWSAHLNVVVLQPDPLSEHIAAVSWLFKESSLFVFKPNEARPICIQRKFCKERIQFAAFVPRDVPETIGSEKYLWLRRSQLFFLTDTQELMTVSTKSAQERLTLSSKQLAVEESLPVTPFSLLLGKHRHQQSQGDVDLGKIVHHHHEQDSPAVKELLHTPAHVLPSASFLCPIFINSLLVSKENKSTEETPDEVEMESEEAEDDSDEENSVTEMKQEDKMPLESLGETTHRLSKSEEKELRKIRKVDYSWISVF", "length": 852, "header": "tr|A0A8V0YHC2-1|A0A8V0YHC2_CHICK Isoform 1 of WD repeat domain 75 OS=Gallus gallus OX=9031 GN=WDR75 PE=1 SV=1 CANONICAL=A0A8V0YHC2-1" }, "locus": { "chromosome": "7", "start_pos": 498226, "end_pos": 481452, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031329.1", "url": "https://www.ensembl.org/id/ENSGALT00010031329.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018269.1", "url": "https://www.ensembl.org/id/ENSGALP00010018269.1" } ] } }, { "isoform_ac": "A0A8V0YK84-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHC2/entry#A0A8V0YK84-1", "sequence": { "sequence": "MVAPAALRVVRCGGRAMHGARAVFSVGARFLLCASGDFVKMYSVATEELVQLLRGHSDLVTGVQLAPHNRLQLYSSSLDGTIKLWDFTDGILIKTFTVGYQLLALYALPSSEDSVFVIIPKSGERDTFQLVSVKLTKAAGQDMEAKELSVVLEGVDASPKCTAFGREGEYVASVKDVNLQVYFFKQKQLNRFSLRATNKKGGNNVFTCVACHPQEDCIATGHADGKIRLWRNFNHKKEYTFSTLHWHHDKVLDLAFSLEGTSLLSGGVESVLVQWHCGSDCKRDFLPRLGSAIEYVSISSDGTFYCTSHTDNRITIINSNLRFSKTIQGLIKARDVKTGLVVDPRTKALVLNGEPGHLQFYCLQSDKQLYSLDIVQQEYIHQAGLNQSDLVRVAFSAQGKWLATVEEREETDLELQLKLWFFDEETQSFKLNTRISMPHEDHITAMCFRDTDEMEDDSLMLVTTGRDCVFKVWVILEDTDPEAQQSLSWSCDFVGSYHSYQATNCCFSEDGSLLAVSFEETVTVWDSSTWDLKCTFCHPPGKISGMECSPQRRRSAT", "length": 557, "header": "tr|A0A8V0YK84-1|A0A8V0YK84_CHICK Computationally mapped isoform of WD repeat domain 75 OS=Gallus gallus OX=9031 GN=WDR75 PE=1 SV=1 CANONICAL=A0A8V0YHC2-1" }, "locus": { "chromosome": "7", "start_pos": 498160, "end_pos": 487562, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031302.1", "url": "https://www.ensembl.org/id/ENSGALT00010031302.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018248.1", "url": "https://www.ensembl.org/id/ENSGALP00010018248.1" } ] } }, { "isoform_ac": "A0A8V0YQ22-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHC2/entry#A0A8V0YQ22-1", "sequence": { "sequence": "MVAPAALRVVRCGGRAMHGARAVFSVGARFLLCASGDFVKMYSVATEELVQLLRGHSDLVTGVQLAPHNRLQLYSSSLDGTIKLWDFTDGILIKTFTVGYQLLALYALPSSEDSVFVIIPKSGERDTFQLVSVKLTKAAGQDMEAKELSVVLEGVDASPKCTAFGREGEYVASVKDVNLQVYFFKQKQLNRFSLRATNKKGGNNVFTCVACHPQEDCIATGHADGKIRLWRNFNHKKEYTFSTLHWHHDKVLDLAFSLEGTSLLSGGVESVLVQWHCGSDCKRDFLPRLGSAIEYVSISSDGTFYCTSHTDNRITIINSNLRFSKTIQGLIKARDVKTGLVVDPRTKALVLNGEPGHLQFYCLQSDKQLYSLDIVQQEYIHQAGLNQSDLVRVAFSAQGKWLATVEEREETDLELQLKLWFFDEETQSFKLNTRISMPHEDHITAMCFRDTDEMEDDSLMLVTTGRDCVFKVWVILEDTDPEAQQSLSWSCDFVGSYHSYQATNCCFSEDGSLLAVSFEETVTVWDSSTWDLKCTFCHPPGKIRFMCT", "length": 548, "header": "tr|A0A8V0YQ22-1|A0A8V0YQ22_CHICK Computationally mapped isoform of WD repeat domain 75 OS=Gallus gallus OX=9031 GN=WDR75 PE=1 SV=1 CANONICAL=A0A8V0YHC2-1" }, "locus": { "chromosome": "7", "start_pos": 498160, "end_pos": 488324, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031291.1", "url": "https://www.ensembl.org/id/ENSGALT00010031291.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018241.1", "url": "https://www.ensembl.org/id/ENSGALP00010018241.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:423985", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423985", "resource": "KEGG Pathway" }, { "id": "R-GGA-6791226", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6791226", "resource": "Reactome", "description": "Major pathway of rRNA processing in the nucleolus and cytosol" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2K9A7-1", "protein_name": "WD repeat-containing protein 75", "gene_name": "Wdr75", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVEERVRVVRCGGSRLNFRRAVFSVDSKYIFCVSGDFIKVYSTATEECVHILRGHKHVVSGILINPNNHLQLYSCSFDGTIKLWDYLDGILIKTFTVGPKLHALFIPAHAEDTVFLTINKEDPDIFQLVSVKLPKSTSRNVEAKELTFVLDYINKSPKSIAFGNEGEYVAAVRDFYLSVYFLKKKKTCNFTLPSTKNKKNARNKFTCVACHPKEDCIASGHMDGKIRLWRNFHDDKLYTYTCLHWHHDMVMDLAFTVTGTSLLSGGQECVLVEWRDGSEKNKEFLPRLGSAIEHISVSPAGDLFCTSHSDNKITVIHRNLDASAVIQGLVKDRSISTGLMVDPRTKALVLNGKPGHLQFYSLQSDKQLYNLDIIQQEYINDQGLIQIELTKAAFGCSGSWLATVEQRQENENELELQMKLWNYSKKTQGFVLNTKISMPHDDHITALCFNNAENYEKPILVTASRDGHFKVWVLTDDSDIYKKAIGWTCDFVGSYHKYQATNCCFSEDGSLLAVSFEEIVTIWDSETWELKCTFCQRAGKIRHLCFGRLTCSKYLLGTTENNLLCCWNLLSCSMQWSAKLNVRVMEADPYSDHIAAVARSSEGSDLFVFKPSEPRPLYIQKNVSREKVQWGVFVPRDVPESFTSEAHQWLNRSQFYFLTESQCLLTFSTKYAEEKLTPTSKQLLAEESLPTTPFSFILGKHRQQQDTKSTETSESELVQLPLTENIPAITELLHTPAHVLPSASFLCTLFVNSLLLSKETKSAEEISDDVDMEGNEESDDSDEEYDLTEKAKETSNPDLGEDAIHQLSKSEEKELRKFRKVDYSWLTAL", "length": 829 }, "evidence": [ { "id": "A0A8V0YHC2", "url": "https://omabrowser.org/oma/group/A0A8V0YHC2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1MCR2-1", "protein_name": "WD repeat-containing protein 75", "gene_name": "WDR75", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MVEEEGIRVVRCGGSELNFRRAVFSADSKYIFCVSGDFIKVYSTATEECVHILQGHRNLVTGIQLNPNNHLQLYSCSVDGTIKLWDYIDGILIKTFRVGCELHALFTLSHAEDSVFVTINKEKPDVFQLASVKLPKSSSQEIEAKELSFVLDYVNQSPKCIAFGNEGEYVAAVRDFYLSVYFFKKKTTTRFTLSSSRNKKHARNNFTCVTCHPKEDCIATGHKDGKIRLWRNFDDEKKYTYTCLHWHHDLVMDLAFSVTGSSLLSGGRESVLVEWREAAEKNKEFLPRLGATIEHISVSPAGDLFCTSHSDNKITIIHRNLEASAVIQGLVKDRSIFTGLMIDPRTKALVLNGKPGHLQFYSLQSDKQLYNLDIIQQEYINDSGLIQIELTKAAFGCYGNWLATVEQRQEKETELELQMKLWMYNKKTQGFVLNTKVNMPHEDHITALCFCNAEKSESSTLVTASKDGHFKVWILTDDSDIYKKAVGWTCDFVGSYHKYQATNCCFSEDGSLLAVSFEEIVTIWDSETWELKCTFCQRAGKIRHLCFGRLTCSKYLLGVTENGILCCWNLLSCALEWSTKLNVRVMEPDPNSENIAAIAQSSVGSDLFVFKPSEPRPLYIQKNICREEVLWGVFVPRDVPESFTSEAYQWLNRSQFYFLTKSQSLLTFSTQSPEEKLTPTSKQLLAEESLPTTPFYFLLGKHRKEQQNDKLNEALENELVQLPLTENIPAISELLRTPAHVLPSASFLCSMFVNSLLLSKETKSAEEHPDDIDMVEEKESDDSDEENNFTEKIQDTNNTDLEEDIIYQLSKSEEKELKKFRKVDYSWIAAL", "length": 831 }, "evidence": [ { "id": "A0A8V0YHC2", "url": "https://omabrowser.org/oma/group/A0A8V0YHC2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F4IRI1-1", "protein_name": "Transducin/WD40 repeat-like superfamily protein", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MKRGGRSYVTSPPSFSNDAKKLLVCTGNTVSVFSAATGLQITSLEGHTAPVTTLIVVPASSPAQKILCYCWTASLDGTIRHWDFSGPELLKTIDAQLPIYSMVIPSLLSEPQQIDKRRELSGKLVAYVSVEDISVVNQGSKELRGHIRRFNLAKSRIPRGDTLKETAEPESIVISPSGEFFGIRHKCKIHIWDVPSGGSRHAVSRKMTLHHTKVINAFAFHPTERVIAAGDVTGRVLIWRGFGNRKLALGNQKKKVRAMVDLDNAGVRGEDDAESCTTWHWHSAEVNVLNFSSDGAYLYSGGREGVLVVWQLDTGKKKFLPRIGSPLLYFMWSPDPTLSSVVCADNQIHLLKMPSMEILRTISGIKPPPSLPRMYEGLASTVAFDRSSGIAALCTENYCVQLYNLLNDRGISEIQVCERNHQPGDEITVVVTAVALSLDGSVMSTTEVKLPEDGIGGLVSLKFWASEPDSKTFTLSTIVYEPHRDAGVSAIVFHPTRSMAVSTSFGGDFKIWVCNSDKNQTDKDSSWICHAVGSYKKKPMTAAAFSGDGTVMAVAAENVITLWNPDKNILLSVLGSTLTPITKLCFAGKSEFLVAASHIPRPELSVWNTSKLSLSWSYGLRIEAVTSAVDSSAFAVLAVIPKTFKTDESKENIFRGRDGAILLFNGSDPKPVSIWTVMKARGGSISFLEGDKSQLRLAYVNGSHEYVVFDPNSDESHERSAVDYDGLAGLEETGDAGYTSLYGQLPDYDKKRMEDVESLGTPFVSSERPWETIFSGSTLNFPPLQKLCAEFFESLMEKRTAVVE", "length": 804 }, "evidence": [ { "id": "A0A8V0YHC2", "url": "https://omabrowser.org/oma/group/A0A8V0YHC2/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q3U821-1", "protein_name": "WD repeat-containing protein 75", "gene_name": "Wdr75", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVEEGVRVVRCGGSRLNFRRAVFSVDSKYIFCVSGDFVKVYSTTTEECVHILHGHTDLVSGILVNPSNHLQLYSCSFDGTIKLWDYVDGILIKTFTIGPKLHAFFIPLHAEDSVFLTISKEEPDIFQLVSVKLPKSTSQDVEARQLTFVLDYINRSPKCIAFGNEGEYVAAVRDFYLSVYFFKKKKTCNFTLPSTKNKKNAKNKFTCVACHPKEDCIASGHMDGKIRLWRNFHSDQKYTYTCLHWHHDMVMDLAFTVTGTSLLSGGRECVLVEWRDGSEKNKEFLPRLGSSIEHISVSPAGDLFCTSHSDNKITVIHRNLDASAVIQGLVKDRSISTGLMVDPRTKALVLNGKPGHLQFYSLQGDKQLYNLDIIQQEYINDEGLTQTELTKAAFGCSGTWLATVEQRQENENELELQMKLWNYSKKTQGFVLNTKIAMPHDDHITALCFNNAESYEKPILVTASRDGHFKVWILTDDSDIYKKAIAWTCDFVGSYHKYQATNCCFSEDGSLLAVSFEEIVTIWDSQTWELKCTFCQRAGKIRHLCFGRLTCSKYLLGTTDNGILCCWNLLSCSIQWSAKLNVRVMEPDPYSDHVAAVAQSSAGSDLFVFKPSEPRPLYIQKNVSREEVQWGVFVPRDVPESFTSETHQWLNRSQFYFLTKSQSLLTFSTKSPEEKLTPTSKQLLAEESLPTTPFSFILGKHRQQQGAKLTETSENELVQLPLTENIPAITELLHTPAHVLPSASFLCSLFVNSLLLSKETKSAEEVPDDVDMEGNKESDDSDEEYDLTEKDKETNNNTDLGEDAIHQLSKSEEKELRKFRKVDYSWLTAL", "length": 830 }, "evidence": [ { "id": "A0A8V0YHC2", "url": "https://omabrowser.org/oma/group/A0A8V0YHC2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q7ZVR1-1", "protein_name": "WD repeat-containing protein 75", "gene_name": "wdr75", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MVEKTDIRVVRCGGSKINFRPPIISHDSRFVLCVSGDSVKVYSTRTEEWLHNLQGHNNQVTGIAFNPANQLQVYSCSADGTVKLWDFIDGILIKTFVIGYPLYSLYVSEKHEGVIFLIVSMVTDSNNESFQLVAVHLPKSAEQEVEAKELSTVASKISPNPSCTAFGRGGEFIAFSRHLQLNVYFFRKQKTYSFSLKATDKKAGKNAFTCVACHPTDDCIASGHEDGKIRLWRNFNHKKEYTYSTKHWHHDAVNHLCFTPEGSNLLSGGIESVLVQWQYGDMSKKEFLPRLGGSISHVSASADGQLFCTAHSDNKISIIESSFKVSGLIQGLVRGDAVSTDLMIDPRSKALVLNGKPGHLQFYSLLRDKHLYNLDIVQQEYIYEAGLDQFEVVKAVFDVKGSWLATVEERGHKTSDLEFFLKLWAFDETTQSFVLNTTVTEAHSERITSMCFSSSEETTMLVTTALDGQFKAWCQTADAQQAQNYWSCDFVGSYHNLKPKNCCFSADGSILAVSFQEVLTLWSPETWELLTTLCQPPGEIRDLCFGRLSCSKYLLSTTTKNLLCCWNLLTCALEWSTSVDVSRLQSDPLSENVAAFSFESKHTHLFVFKPSEPRPLFSQRYVCLERVDRAVFVPREEPFNSCDESCQWLNRSQLYFLTHNMDLLTFSSATEEDRMLSSSKRLVIDESVAVTPFYLLLGRHRKQQHKLNTETQEPADKPQHTQGSVTIKQLLHTPAHVLPAASVLCSMFVRSLLISNTGVREEMDSSEQEMDSEKEEEESEEEMEACDGQQELRAQGSVDEQKPKLSKAQERELKSLRKTDFSWMTSLIDSKP", "length": 832 }, "evidence": [ { "id": "A0A8V0YHC2", "url": "https://omabrowser.org/oma/group/A0A8V0YHC2/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q8IWA0-1", "protein_name": "WD repeat-containing protein 75", "gene_name": "WDR75", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVEEENIRVVRCGGSELNFRRAVFSADSKYIFCVSGDFVKVYSTVTEECVHILHGHRNLVTGIQLNPNNHLQLYSCSLDGTIKLWDYIDGILIKTFIVGCKLHALFTLAQAEDSVFVIVNKEKPDIFQLVSVKLPKSSSQEVEAKELSFVLDYINQSPKCIAFGNEGVYVAAVREFYLSVYFFKKKTTSRFTLSSSRNKKHAKNNFTCVACHPTEDCIASGHMDGKIRLWRNFYDDKKYTYTCLHWHHDMVMDLAFSVTGTSLLSGGRESVLVEWRDATEKNKEFLPRLGATIEHISVSPAGDLFCTSHSDNKIIIIHRNLEASAVIQGLVKDRSIFTGLMIDPRTKALVLNGKPGHLQFYSLQSDKQLYNLDIIQQEYINDYGLIQIELTKAAFGCFGNWLATVEQRQEKETELELQMKLWMYNKKTQGFILNTKINMPHEDCITALCFCNAEKSEQPTLVTASKDGYFKVWILTDDSDIYKKAVGWTCDFVGSYHKYQATNCCFSEDGSLLAVSFEEIVTIWDSVTWELKCTFCQRAGKIRHLCFGRLTCSKYLLGATENGILCCWNLLSCALEWNAKLNVRVMEPDPNSENIAAISQSSVGSDLFVFKPSEPRPLYIQKGISREKVQWGVFVPRDVPESFTSEAYQWLNRSQFYFLTKSQSLLTFSTKSPEEKLTPTSKQLLAEESLPTTPFYFILGKHRQQQDEKLNETLENELVQLPLTENIPAISELLHTPAHVLPSAAFLCSMFVNSLLLSKETKSAKEIPEDVDMEEEKESEDSDEENDFTEKVQDTSNTGLGEDIIHQLSKSEEKELRKFRKIDYSWIAAL", "length": 830 }, "evidence": [ { "id": "A0A8V0YHC2", "url": "https://omabrowser.org/oma/group/A0A8V0YHC2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "positive regulation of rRNA processing", "id": "GO:2000234", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000234", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHC2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHC2" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHC2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHC2" } ], "pmid": "" }, { "name": "rRNA processing", "id": "GO:0006364", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006364", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHC2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHC2" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase I", "id": "GO:0045943", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045943", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHC2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHC2" } ], "pmid": "" }, { "name": "ribosomal small subunit biogenesis", "id": "GO:0042274", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042274", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHC2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHC2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHC2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHC2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHC2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHC2" } ], "pmid": "" }, { "name": "small-subunit processome", "id": "GO:0032040", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032040", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHC2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHC2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 408, "end_pos": 410, "annotation": "n_glycosylation_sequon" }, { "start_pos": 782, "end_pos": 784, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YHC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHC2" }, { "id": "PF23769", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23769" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "WD 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"negative regulation of angiogenesis", "id": "GO:0016525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016525", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHD2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHD2" } ], "pmid": "" }, { "name": "fat cell differentiation", "id": "GO:0045444", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045444", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHD2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHD2" } ], "pmid": "" }, { "name": "stem cell population maintenance", "id": "GO:0019827", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019827", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHD2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHD2" } ], "pmid": "" }, { "name": "regulation of cell differentiation", "id": "GO:0045595", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045595", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHD2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHD2" } ], "pmid": "" }, { "name": "positive regulation of hemoglobin biosynthetic process", "id": "GO:0046985", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046985", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHD2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHD2" } ], "pmid": "" }, { "name": "canonical Wnt signaling pathway", "id": "GO:0060070", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060070", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHD2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHD2" } ], "pmid": "" }, { "name": "negative regulation of heterotypic cell-cell adhesion", "id": "GO:0034115", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034115", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHD2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHD2" } ], "pmid": "" }, { "name": "negative regulation of response to cytokine stimulus", "id": "GO:0060761", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060761", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHD2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHD2" } ], "pmid": "" }, { "name": "negative regulation of G1/S transition of mitotic cell cycle", "id": "GO:2000134", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000134", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHD2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHD2" } ], "pmid": "" }, { "name": "negative regulation of extrinsic apoptotic signaling pathway in absence of ligand", "id": "GO:2001240", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2001240", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHD2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHD2" } ], "pmid": "" }, { "name": "cellular response to laminar fluid shear stress", "id": "GO:0071499", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071499", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHD2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHD2" } ], "pmid": "" }, { "name": "negative regulation of interleukin-8 production", "id": "GO:0032717", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032717", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHD2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHD2" } ], "pmid": "" }, { "name": "positive regulation of miRNA transcription", "id": "GO:1902895", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902895", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHD2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHD2" } ], "pmid": "" }, { "name": "defense response to tumor cell", "id": "GO:0002357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002357", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHD2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHD2" } ], "pmid": "" }, { "name": "post-embryonic hemopoiesis", "id": "GO:0035166", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035166", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHD2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHD2" } ], "pmid": 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This record is derived from a genomic sequence (NC_052580.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040533957", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040533957" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHD7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHD7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "IER5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHD7", "locus": { "chromosome": "8", "start_pos": 5802460, "end_pos": 5803167, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010014329", "url": "https://www.ensembl.org/id/ENSGALG00010014329" } ] } } ], "crossref": [ { "id": "A0A8V0YHD7", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YHD7", "database": 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"MEFKLEAHRIVSISLGKIYNSRVQRGGIKLHKNLLVSLVLRSARQVYLSDPCPGLYLAGPAGTPAPPPQQQPGEPAAGPPAGWGEPPPPAARASWPETEPQPERSSVSDAPRVGDEVPVATVTGVGDVFQGGEADATEAAWSRVEGPRQAAAREAEGTAGGWGVFPEVSRAARRPCGCPLGGEDPPGTPAATPRAACCCAPQPAEDEPPAPPAVCPRKRCAAGVGGGPAGCPAPGSTPLKKPRRNLEQPPSGGEDDDAEEMETGNVANLISIFGSSFSGLLRKSPGGGREEEEGEESGPEAAEPGQICCDKPVLRDMNPWSTAIVAF", "length": 327 }, "evidence": [ { "id": "A0A8V0YHD7", "url": "https://omabrowser.org/oma/group/A0A8V0YHD7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHD7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHD7" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHD7", 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"url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034605", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHD7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHD7" } ], "pmid": "" }, { "name": "positive regulation of cellular response to heat", "id": "GO:1900036", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1900036", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHD7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHD7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHD7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHD7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YHE7-1", "uniprot_ac": "A0A8V0YHE7", "uniprot_id": "A0A8V0YHE7_CHICK", "mass": { "chemical_mass": 92881.0, "monoisotopic_mass": 92881.0 }, "refseq": {}, "gene_names": [ { "name": "SGSM3", "type": "recommended", "evidence": [ { "id": "A0A8V0YHE7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHE7" } ] } ], "protein_names": [ { "name": "RUN and TBC1 domain-containing protein 3", "type": "recommended", "evidence": [ { "id": "A0A8V0YHE7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHE7/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHE7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHE7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SGSM3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHE7", "locus": { "chromosome": "1", "start_pos": 50101985, "end_pos": 50128451, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013084", "url": "https://www.ensembl.org/id/ENSGALG00010013084" } ] } } ], "crossref": [ { "id": "A0A8V0YHE7", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YHE7", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd11813", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11813", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd17688", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd17688", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "418008", "url": "https://www.ncbi.nlm.nih.gov/gene/418008", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000195", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000195", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004012", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004012", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035833", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035833", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035969", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035969", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036028", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036028", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037213", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037213", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050302", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050302", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:418008", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418008", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "EIVQKWY", "url": "https://omabrowser.org/oma/group/EIVQKWY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YBZ6", "url": "https://www.orthodb.org/?gene=A0A8V0YBZ6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YHE7", "url": "https://www.orthodb.org/?gene=A0A8V0YHE7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47219", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47219", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47219:SF13", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47219:SF13", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00018", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00018", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00566", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00566", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02759", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02759", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YBZ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBZ6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YBZ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBZ6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHE7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHE7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHE7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHE7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSGHHTPSAGGPFSALTPSIWPQEILAKYTQKEESIEQPEFRYDEFGFRVDKEDSAEPNSSKLLGLPLTEEPQQRLKWQAHLEFTHNHDVGDLTWDKIEVTLPHSDKLRSLVLAGIPHSMRPQLWMRLSGALQKKRNSEMSYRDIVKNSSNDETIAAKQIEKDLLRTMPSNACFSNMNSIGVPRLRRILRGLAWLYPEIGYCQGTGMVAASLLLFLEEEDAFWMMCAIIEELVPASYFSTTLMGVQTDQRVLRQLIVQYLPRLDKLLQEHDIELSLITLHWFLTSFASVVHIKLLLRIWDLFFYEGSLVLFQLTLGMLSMKEDELIQSENSASIFNTLSDIPSQIEDADVLLREAMRVAGSLTDVAVETQRRKHLAYLIADQGQLLNSSTTVNNLSKIVRRRTQRRKSGITSLLFGDDDLEALKAKNIKQTELVADLREAILQVARHFQCVDPKNCSIDLTPDYSMESHQRDHENYVACSRNRRRRAKALLDFERHDDDELGFRKNDIITIISQKDEHCWVGELNGLRGWFPAKFVEILDERSKEYSIAGDDSVTEGVTDLVRGTLCPALKSIFEHGLKKPSLLGGACHPWLFIEEAASREVERDFDSVYSRLVLCKTYRLDEDGKVLTPEELLYRAVQAVNMTHDAAHAQMDVKLRSLICVGLNEQVLHLWLEVLCSSLQTVEKWFHPWSFLRSPGWVQIKCELSALQICLQPVSGLGAANKEGGEGEETAEGRRAGHARETPPLQLGHRWVTSTPLCPGSLLRGVHSFPQPPSSHIPFLHFLPLPTLVSVTESPRGAASPPGTDAAWPCGTAARPEGGDGRG", "length": 824, "header": "tr|A0A8V0YHE7-1|A0A8V0YHE7_CHICK Isoform 1 of RUN and TBC1 domain-containing protein 3 OS=Gallus gallus OX=9031 GN=SGSM3 PE=1 SV=1 CANONICAL=A0A8V0YHE7-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YBZ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHE7/entry#A0A8V0YBZ6-1", "sequence": { "sequence": "MSGHHTPSAGGPFSALTPSIWPQEILAKYTQKEESIEQPEFRYDEFGFRVDKEDSAEPNSSKLLGLPLTEEPQQRLKWQAHLEFTHNHDVGDLTWDKIEVTLPHSDKLRSLVLAGIPHSMRPQLWMRLSGALQKKRNSEMSYRDIVKNSSNDETIAAKQIEKDLLRTMPSNACFSNMNSIGVPRLRRILRGLAWLYPEIGYCQGTGMVAASLLLFLEEEDAFWMMCAIIEELVPASYFSTTLMGVQTDQRVLRQLIVQYLPRLDKLLQEHDIELSLITLHWFLTSFASVVHIKLLLRIWDLFFYEGSLVLFQLTLGMLSMKEDELIQSENSASIFNTLSDIPSQIEDADVLLREAMRVAGSLTDVAVETQRRKHLAYLIADQGQLLNSSTTVNNLSKIVRRRTQRRKSGITSLLFGDDDLEALKAKNIKQTELVADLREAILQVARHFQCVDPKNCSIDLTPDYSMESHQRDHENYVACSRNRRRRAKALLDFERHDDDELGFRKNDIITIISQKDEHCWVGELNGLRGWFPAKFVEILDERSKEYSIAGDDSVTEGVTDLVRGTLCPALKSIFEHGLKKPSLLGGACHPWLFIEEAASREVERDFDSVYSRLVLCKTYRLDEDGKVLTPEELLYRAVQAVNMTHDAAHAQMDVKLRSLICVGLNEQVLHLWLEVLCSSLQTVEKWFHPWSFLRSPGWVQIKCELRVLCKFAFSLSQDWELPIKREEKEKKPLKEGVQDMLVKHHLFSWDIDG", "length": 753, "header": "tr|A0A8V0YBZ6-1|A0A8V0YBZ6_CHICK Computationally mapped isoform of Small G protein signaling modulator 3 OS=Gallus gallus OX=9031 GN=SGSM3 PE=1 SV=1 CANONICAL=A0A8V0YHE7-1" }, "locus": { "chromosome": "1", "start_pos": 50121497, "end_pos": 50103067, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031363.1", "url": "https://www.ensembl.org/id/ENSGALT00010031363.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018295.1", "url": "https://www.ensembl.org/id/ENSGALP00010018295.1" } ] } }, { "isoform_ac": "A0A8V0YHE7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHE7/entry#A0A8V0YHE7-1", "sequence": { "sequence": "MSGHHTPSAGGPFSALTPSIWPQEILAKYTQKEESIEQPEFRYDEFGFRVDKEDSAEPNSSKLLGLPLTEEPQQRLKWQAHLEFTHNHDVGDLTWDKIEVTLPHSDKLRSLVLAGIPHSMRPQLWMRLSGALQKKRNSEMSYRDIVKNSSNDETIAAKQIEKDLLRTMPSNACFSNMNSIGVPRLRRILRGLAWLYPEIGYCQGTGMVAASLLLFLEEEDAFWMMCAIIEELVPASYFSTTLMGVQTDQRVLRQLIVQYLPRLDKLLQEHDIELSLITLHWFLTSFASVVHIKLLLRIWDLFFYEGSLVLFQLTLGMLSMKEDELIQSENSASIFNTLSDIPSQIEDADVLLREAMRVAGSLTDVAVETQRRKHLAYLIADQGQLLNSSTTVNNLSKIVRRRTQRRKSGITSLLFGDDDLEALKAKNIKQTELVADLREAILQVARHFQCVDPKNCSIDLTPDYSMESHQRDHENYVACSRNRRRRAKALLDFERHDDDELGFRKNDIITIISQKDEHCWVGELNGLRGWFPAKFVEILDERSKEYSIAGDDSVTEGVTDLVRGTLCPALKSIFEHGLKKPSLLGGACHPWLFIEEAASREVERDFDSVYSRLVLCKTYRLDEDGKVLTPEELLYRAVQAVNMTHDAAHAQMDVKLRSLICVGLNEQVLHLWLEVLCSSLQTVEKWFHPWSFLRSPGWVQIKCELSALQICLQPVSGLGAANKEGGEGEETAEGRRAGHARETPPLQLGHRWVTSTPLCPGSLLRGVHSFPQPPSSHIPFLHFLPLPTLVSVTESPRGAASPPGTDAAWPCGTAARPEGGDGRG", "length": 824, "header": "tr|A0A8V0YHE7-1|A0A8V0YHE7_CHICK Isoform 1 of RUN and TBC1 domain-containing protein 3 OS=Gallus gallus OX=9031 GN=SGSM3 PE=1 SV=1 CANONICAL=A0A8V0YHE7-1" }, "locus": { "chromosome": "1", "start_pos": 50121497, "end_pos": 50102852, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031367.1", "url": "https://www.ensembl.org/id/ENSGALT00010031367.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018299.1", "url": "https://www.ensembl.org/id/ENSGALP00010018299.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:418008", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418008", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "Q2KI13-1", "protein_name": "Small G protein signaling modulator 3", "gene_name": "SGSM3", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSGSHVPSANGPFSALTPSMWPQEILAKYAQEEATVEQPEFRYDEFGFRVDKEDADGIPYSGQLLEDPPQRLRWQAHLEFTHNHDVGDLTWDKIAVSLPRSEKLRSLVLAGVPHSMRPQLWMRLSGALQKKRNSELSYREIVKNSSNDETIAAKQIEKDLLRTMPSNACFAHVSGVGVPRLRRVLRALAWLYPEIGYCQGTGMVAACLLLFLEEDDAFWMMCAIIEDLLPASYFSTTLLGVQTDQRVLRHLIVQYLPRLDRLLQEHDIELSLITLHWFLTAFASVVHIRLLLRLWDLFFYEGSLVLFQATLGMLRLKEDELIQSENSASIFNTLSDIPSQLEDADLLLAEAMRLAGSLTAVAVETQRRKHLAYLLADQGQLLGAPATTGLSQVVRRRTQRRKSGITSLLFGEDDLEAMKAKNIKQTELVADLREAILRVARHFQCTDPKNCNVELTPDYSMESHQRDHESYVACSRGHPRRAKALLDFERHDDDELGFRKNDIITIVSQKDEHCWVGELNGLRGWFPAKFVEVLDERSKEYSIAGDDAVTEGVTDLVRGTLCPALKALLEHGLKKPSLLGGACHPWLFIEEAAGREVERDFDSVYSRLVLCKTYRLDEDGKVLTPEELLYRAVQSVNVTHDAAHAQMDVKLRSLICVGLNEQVLHLWLEVLCSSLPTVEKWYQPWSFLRSPGWVQIKCELRVLCCFAFSLSQDWELPAKREEEKKPLKEGVQDMLVKHHLFSWDIDG", "length": 747 }, "evidence": [ { "id": "A0A8V0YHE7", "url": "https://omabrowser.org/oma/group/A0A8V0YHE7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q6P6R7-1", "protein_name": "Small G protein signaling modulator 3", "gene_name": "Sgsm3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSGNHTPSASGPFSALTPSIWPQEILAKSSQKEDSSEPEICYDEFGFRVDKEGSEPGCSQMAGTPLVEDPPQRLRWQAHLEFTHNHDVGDLTWDKIAVSLPRSEKLRSLVLAGIPHGMRPQLWMRLSGALQKKKNSELSYREIVKNSSNDETIAAKQIEKDLLRTMPSNACFANVNSIGVPRLRRVLRALAWLYPEIGYCQGTGMVAACLLLFLEEEDAFWMMCAIIEDLLPASYFSTTLLGVQTDQRVLRHLIVQYLPRLDKLLQEHDIELSLITLHWFLTAFASVVHIRLLLRIWDLFFYEGSLVLFQTTLGMLRLKEEELIQSENSASIFNTLSDIPAQMDDAELLLGEAMQLAGSLTDVAVETQRRKHLAYLIADQGQTLGTSTTTSLSQVVRRRTQRRKSGITSLLFGEDDLEALKAKNIKQTELVADLREAILRVARHFQCTDPKNCSVELTPDYSMESHQRDHENYVACLRSHRRRAKALLDFERHDDDELGFRKNDIITIISQKDEHCWVGELNGLRGWFPAKFVEVLDERSKEYSIAGDDSVTEGVTDLVRGTLCPALKALFEHGLKKPSLLGGACHPWLFIEEAAGREVERDFDSVYSRLVLCKTYRLDEDGKVLTPEELLYRAVQSVNVTHDAAHAQMDVKLRSLICVGLNEQVLHLWLEVLCSSLPTVEKWYQPWSFLRSPGWVQIKCELRVLCCFAFSLSQDWELPAKREEEKQPLKEGVQDMLVKHHLFSWDIDG", "length": 749 }, "evidence": [ { "id": "A0A8V0YHE7", "url": "https://omabrowser.org/oma/group/A0A8V0YHE7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q7T2D0-1", "protein_name": "Small G protein signaling modulator 3", "gene_name": "sgsm3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSGSYTPAPGGPFSALTPSMWPQDILAKYCQKDPGTEVELQYDEFGFRIDSEDGVETRKWLCGDGAPQREDPQQRLRWQAHLEFTHNHTVGDLTWDKITPTLARSDRLRSLVLGGIPHSMRPQLWMRLSGALQKKRTSDISYREIVKNSSNDDTTAAKQIEKDLLRTMPTNACFNTLTSVGVPKLRRVLRGLAWLYPDIGYCQGTGMVVSCLLLFLEEEDALWMMCALIEDLLPPSYFSSTLLGVQTDQRVLRQLIVQYLPRLDKLLQEHDIELSLITLHWFLTAFASVVDIRILLRIWDLLFYEGSMVLFQVTLGMLKIKEDELVSSENSASIFNTLSDLPSQLEDGAAVLGEAVRLAGSLSQENLDTHRHKHLAYILAEQAQLNSNNSHSLNTNLNKVVRRQNMRRKSTLSSLLWGEDEVEALKAKNIKQTELVAALREAINRTAEHFHCLDPRNCSTDLTPDYSMESHQRDHENFLVVSRNRRRRAKALLDFERHDDDELGFRKNDIITIISQKDEHCWVGELNGLRGWFPAKFVEILDERSKEYSLAGDDTVTEAVNDLVRGSLCPALKAIFQHGLKKPSILGGPCHPWLFIEEAASKEVERDFNSVYSRLVLCKTYRLDEDGKVLTPEELLYRAVQSVNMSHDTAHVQMDVKFRSLICVGLNEQVLHLWLEVLCSSMSAVEKWYHPWSFLRSPGWVQIKCELRVLSKFAFSLSQDCELPTKKEEKEQRPLKEGVQDMLVKHHLFSWDIDG", "length": 755 }, "evidence": [ { "id": "A0A8V0YHE7", "url": "https://omabrowser.org/oma/group/A0A8V0YHE7/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q8VCZ6-1", "protein_name": "Small G protein signaling modulator 3", "gene_name": "Sgsm3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSGNHTPSASGPFSALTPSIWPQEILAKYSQKEESSEQPELCYDEFGFRVDKEGSEPGCSQMTGSPLVEDPPQRLRWQAHLEFTHNHDVGDLTWDKIAVSLPRSEKLRSLVLAGIPHGMRPQLWMRLSGALQKKKNSELSYREIIKNSSNDETIAAKQIEKDLLRTMPSNACFANVNSIGVPRLRRVLRALAWLYPEIGYCQGTGMVAACLLLFLEEEDAFWMMCAIIEDLLPASYFSTTLLGVQTDQRVLRHLIVQYLPRLDKLLQEHDIELSLITLHWFLTAFASVVHIRLLLRIWDLFFYEGSLVLFQTTLGMLRLKEEELIQSENSASIFNTLSDIPAQMDDAELLLGEAMRLAGSLTDVAVETQRRKHLAYLIADQGQTLGTGTTTNLSQVVRRRTQRRKSGITSLLFGEDDLEALKAKNIKQTELVADLREAILRVARHFQCTDPKNCSVELTPDYSMESHQRDHENYVACLRSHRRRAKALLDFERHDDDELGFRKNDIITIISQKDEHCWVGELNGLRGWFPAKFVEVLDERSKEYSIAGDDSVTEGVTDLVRGTLCPALKALFEHGLKKPSLLGGACHPWLFIEEAAGREVERDFDSVYSRLVLCKTYRLDEDGKVLTPEELLYRAVQSVNVTHDAAHAQMDVKLRSLICVGLNEQVLHLWLEVLCSSLPTVEKWYQPWSFLRSPGWVQIKCELRVLCCFAFSLSQDWELPARREEEKQPLKEGVQDMLVKHHLFSWDIDG", "length": 750 }, "evidence": [ { "id": "A0A8V0YHE7", "url": "https://omabrowser.org/oma/group/A0A8V0YHE7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96HU1-1", "protein_name": "Small G protein signaling modulator 3", "gene_name": "SGSM3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSGSHTPACGPFSALTPSIWPQEILAKYTQKEESAEQPEFYYDEFGFRVYKEEGDEPGSSLLANSPLMEDAPQRLRWQAHLEFTHNHDVGDLTWDKIAVSLPRSEKLRSLVLAGIPHGMRPQLWMRLSGALQKKRNSELSYREIVKNSSNDETIAAKQIEKDLLRTMPSNACFASMGSIGVPRLRRVLRALAWLYPEIGYCQGTGMVAACLLLFLEEEDAFWMMSAIIEDLLPASYFSTTLLGVQTDQRVLRHLIVQYLPRLDKLLQEHDIELSLITLHWFLTAFASVVDIKLLLRIWDLFFYEGSRVLFQLTLGMLHLKEEELIQSENSASIFNTLSDIPSQMEDAELLLGVAMRLAGSLTDVAVETQRRKHLAYLIADQGQLLGAGTLTNLSQVVRRRTQRRKSTITALLFGEDDLEALKAKNIKQTELVADLREAILRVARHFQCTDPKNCSVELTPDYSMESHQRDHENYVACSRSHRRRAKALLDFERHDDDELGFRKNDIITIVSQKDEHCWVGELNGLRGWFPAKFVEVLDERSKEYSIAGDDSVTEGVTDLVRGTLCPALKALFEHGLKKPSLLGGACHPWLFIEEAAGREVERDFASVYSRLVLCKTFRLDEDGKVLTPEELLYRAVQSVNVTHDAVHAQMDVKLRSLICVGLNEQVLHLWLEVLCSSLPTVEKWYQPWSFLRSPGWVQIKCELRVLCCFAFSLSQDWELPAKREAQQPLKEGVRDMLVKHHLFSWDVDG", "length": 749 }, "evidence": [ { "id": "A0A8V0YHE7", "url": "https://omabrowser.org/oma/group/A0A8V0YHE7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VFB6-1", "protein_name": "Small G protein signaling modulator 3", "gene_name": "Dmel\\CG12241", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MDMARSIFGRDHEGYVGREEHTRKLQNLGSEDDLGELPPMMEELSVADGLRPNPGGPFSALTASMWPQEILAKLGGGAELASGPNDQPEYRFDEFGFRVEEEDGPEQSSNKLLSIPFVEDAQQRLQWIAHLEFSHNKEAAELSWEHVDVMLPRTEKLRNMVRQGIPHTLRAQMWMRLSGALAKKQKSETSYHDIVKASSNDQLMTSKQIEKDLLRILPTNACFSNPNGTGIPRLRRILRGIAWLFPDIGYCQGTGVIVACLLLFMEEENAFWMMATIVEDLLPASYYSSTLLGIQADQRVMHTLIANYLSSVDESLRKHDIELSLITLHWFLTLFANVVHMKILVRIWDWFFYEGSIVLFQLTLGMLKVKEQDLKHLENSAQIFNSLSDIPGEVTDVEVLFRQALEVGGSLSQTVIDTHRRRHLAYLMADQGHQIGNPEAAPNLPKQQLARRQVRKSKSILEAFLFRGDGNEGDQLKNKNIRQTEILVDLREAILKVGRHFITIEPKLAGHIQLTANYSTESHAKDHENFINVARTRKRRAKALHDFERHDDDELGFRRNDIITIISQKDEHCWVGELNGLRGWFPAKFVELLDERSKLYTSAGDDAISETVTDLVRGTLAPAIKAFLEHGMKRPTFLGGPIHPWLYIEEAATREVEKDFESVYSRLVLCKTYRLDEDGKVLTPEELLYRCVQAINQTHDDAHAQMDVKLRSLICLGLNEQVLHLWLEVLCACQEVVQKWYHSWSFIDSPGWVQIKCELRILSQFAFNLNPDWELPPKRGKESQPLKDGVRDMLVKHHLFSWDL", "length": 804 }, "evidence": [ { "id": "A0A8V0YHE7", "url": "https://omabrowser.org/oma/group/A0A8V0YHE7/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "regulation of Rab protein signal transduction", "id": "GO:0032483", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032483", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHE7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHE7" } ], "pmid": "" }, { "name": "Rap protein signal transduction", "id": "GO:0032486", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032486", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHE7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHE7" } ], "pmid": "" }, { "name": "regulation of endocytosis", "id": "GO:0030100", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030100", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHE7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHE7" } ], "pmid": "" }, { "name": "endosomal transport", "id": "GO:0016197", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016197", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHE7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHE7" } ], "pmid": "" }, { "name": "positive regulation of protein catabolic process", "id": "GO:0045732", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045732", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHE7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHE7" } ], "pmid": "" }, { "name": "plasma membrane to endosome transport", "id": "GO:0048227", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048227", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHE7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHE7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHE7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHE7" } ], "pmid": "" }, { "name": "small GTPase binding", "id": "GO:0031267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031267", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHE7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHE7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHE7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHE7" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHE7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHE7" } ], "pmid": "" }, { "name": "gap junction", "id": "GO:0005921", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005921", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHE7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHE7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 148, "end_pos": 150, "annotation": "n_glycosylation_sequon" }, { "start_pos": 387, "end_pos": 389, "annotation": "n_glycosylation_sequon" }, { "start_pos": 394, "end_pos": 396, "annotation": "n_glycosylation_sequon" }, { "start_pos": 455, "end_pos": 457, "annotation": "n_glycosylation_sequon" }, { "start_pos": 59, "end_pos": 61, "annotation": "n_glycosylation_sequon" }, { "start_pos": 642, "end_pos": 644, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YHE7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHE7" }, { "id": "PS50826", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50826" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RUN", "eco_id": "ECO_0000259", "start_pos": 557, "end_pos": 725, "start_aa": "Gly", "end_aa": "Gly", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0YHE7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHE7" }, { "id": "PS50086", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50086" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Rab-GAP TBC", "eco_id": "ECO_0000259", "start_pos": 115, "end_pos": 306, "start_aa": "Gly", "end_aa": "Gly", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0YHE7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHE7" }, { "id": "PS50002", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50002" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SH3", "eco_id": "ECO_0000259", "start_pos": 482, "end_pos": 541, "start_aa": "Asn", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 148, "end_pos": 150 }, { "start_pos": 387, "end_pos": 389 }, { "start_pos": 394, "end_pos": 396 }, { "start_pos": 455, "end_pos": 457 }, { "start_pos": 59, "end_pos": 61 }, { "start_pos": 642, "end_pos": 644 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YID3-1", "uniprot_ac": "A0A8V0YID3", "uniprot_id": "A0A8V0YID3_CHICK", "mass": { "chemical_mass": 25084.0, "monoisotopic_mass": 25084.0 }, "refseq": {}, "gene_names": [ { "name": "CXCL14", "type": "recommended", "evidence": [ { "id": "A0A8V0YID3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YID3" } ] } ], "protein_names": [ { "name": "C-X-C motif chemokine ligand 14", "type": "synonym", "evidence": [ { "id": "A0A8V0YID3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YID3/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YID3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YID3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CXCL14", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YID3", "locus": { "chromosome": "13", "start_pos": 14943824, "end_pos": 14933731, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013086", "url": "https://www.ensembl.org/id/ENSGALG00010013086" } ] } } ], "crossref": [ { "id": "A0A8V0YID3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YID3", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR001811", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001811", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036048", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036048", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YHF4", "url": "https://www.orthodb.org/?gene=A0A8V0YHF4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YID3", "url": "https://www.orthodb.org/?gene=A0A8V0YID3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PF00048", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00048", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YHF4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHF4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHF4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHF4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YID3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YID3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YID3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YID3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "SHHPFHRVSLLSANRRCLPQPGEPPPTPIPKAAAQQKPNGAAAAASPPARPVPPRRPPLPPGLRSGGSRAAPHVNEAAARAAGAHLKGDERGGTRQSSGSSTARSRSFPPRGREHKTEPRCARSGTCRLAMKLLTAALLLLVIAMCLASAEGVKCKCSRKGPKIRFSNVRKLEIKPRYPFCVEEMIIVTLWTKVRGEQQHCLNPKRQNTVRLLKWYRVWKEKGRVYEE", "length": 228, "header": "tr|A0A8V0YID3-1|A0A8V0YID3_CHICK Isoform 1 of C-X-C motif chemokine ligand 14 OS=Gallus gallus OX=9031 GN=CXCL14 PE=4 SV=1 CANONICAL=A0A8V0YID3-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YHF4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YID3/entry#A0A8V0YHF4-1", "sequence": { "sequence": "MLHLLLSQMMRTFLNTALCLNNRREHKTEPRCARSGTCRLAMKLLTAALLLLVIAMCLASAEGVKCKCSRKGPKIRFSNVRKLEIKPRYPFCVEEMIIVTLWTKVRGEQQHCLNPKRQNTVRLLKWYRVWKEKGRVYEE", "length": 139, "header": "tr|A0A8V0YHF4-1|A0A8V0YID3_CHICK Computationally mapped isoform of C-X-C motif chemokine ligand 14 OS=Gallus gallus OX=9031 GN=CXCL14 PE=4 SV=1 CANONICAL=A0A8V0YID3-1" }, "locus": { "chromosome": "13", "start_pos": 14942685, "end_pos": 14934506, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031375.1", "url": "https://www.ensembl.org/id/ENSGALT00010031375.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018304.1", "url": "https://www.ensembl.org/id/ENSGALP00010018304.1" } ] } }, { "isoform_ac": "A0A8V0YID3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YID3/entry#A0A8V0YID3-1", "sequence": { "sequence": 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Activates the ERK and JNK kinase pathways by phosphorylation of MAP2K1 and MAP2K4. May phosphorylate the MAPK8/JNK1 kinase. Activates CHUK and IKBKB, the central protein kinases of the NF-kappa-B pathway.", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PDJ5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PDJ5#function" }, { "database": "UniProtKB", "id": "ARBA00054158", "url": "https://www.uniprot.org/uniprotkb/ARBA00054158#function" }, { "database": "UniProtKB", "id": "A0A8V0YHH8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHH8#function" }, { "database": "UniProtKB", "id": "A0A8V0YIE3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIE3#function" }, { "database": "UniProtKB", "id": "A0A8V0YIF7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIF7#function" }, { "database": "UniProtKB", "id": "A0A8V0YKF0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKF0#function" }, { "database": "UniProtKB", "id": "A0A8V0YKF5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKF5#function" }, { "database": "UniProtKB", "id": "F1N938", "url": "https://www.uniprot.org/uniprotkb/F1N938#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIE3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIE3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MAP3K1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIE3", "locus": { "chromosome": "Z", "start_pos": 18006015, "end_pos": 17948529, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013033", "url": "https://www.ensembl.org/id/ENSGALG00010013033" } ] } } ], "crossref": [ { "id": "ENSGALG00000014718", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000014718", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd06630", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06630", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd16494", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16494", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "427144", "url": "https://www.ncbi.nlm.nih.gov/gene/427144", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000719", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000719", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001841", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001841", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007527", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007527", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008271", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008271", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011009", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011009", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017441", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017441", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050538", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050538", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PDJ5", "url": "https://www.orthodb.org/?gene=A0A1D5PDJ5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YHH8", "url": "https://www.orthodb.org/?gene=A0A8V0YHH8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YIE3", "url": "https://www.orthodb.org/?gene=A0A8V0YIE3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YIF7", "url": "https://www.orthodb.org/?gene=A0A8V0YIF7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YKF0", "url": "https://www.orthodb.org/?gene=A0A8V0YKF0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YKF5", "url": "https://www.orthodb.org/?gene=A0A8V0YKF5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1N938", "url": "https://www.orthodb.org/?gene=F1N938", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48016", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48016", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00069", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00069", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF04434", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04434", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF28295", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF28295", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-2871796", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2871796", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A1D5PDJ5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PDJ5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PDJ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PDJ5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHH8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHH8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHH8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHH8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YIE3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIE3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YIE3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIE3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YIF7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIF7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YIF7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIF7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YKF0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKF0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YKF0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKF0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YKF5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKF5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YKF5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKF5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N938", "url": "https://www.uniprot.org/uniprotkb/F1N938", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N938-1", "url": "https://www.uniprot.org/uniprotkb/F1N938-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "QGSCAAAYECGFLGDLADSSTESGNLLDCSRDMENKETLRGLQKMDDRPEERMIREKLKATCMPAWKHEWLERRSRRGPVVVKPIPVKGDGSEMNKLSLEPQSEGQSSASSPTQKGRRSPSPSSSSSSSSRTVKSESPGVRRKRVSPVPFQSGRITPPRRAPSPDGFSPYSPEETSRRVNKVMRARLYLLQQIGPNSFLIGGDSPDNKYRVFIGPQTCSCGRGTFCIHLLFVMLRVFQLEPSDPMLWRKTLKNFEVESLFQKYHSRRSSRIKAPSRNTIQKFVSRMSNSHTLSSSTSTSSSENSMKDEEEQMCPICLLGMLDEESLTVCEDGCRNKLHHHCMSIWAEECRRNREPLICPLCRSKWRSHDFYSHELPSPVDSSVLHVVQQQTQQQSTIGSQRRTQDSNFNLTHYGVQQIPSAYKDLAEPWIQVFGMELVGCLFSRNWNIREMALRRLSHDVSGALLLANGESTGSSGNSNGNNTSAGALGIASGSSQATVSGDVVVESCCSVLSMVCADPVYKVYVAALKTLRAMLVYTPCHSLAERTKLQRLLKPVVETILVKCADANSRTSQLSVSTLLEMCKGQAGELAVGREILKSGSIGIGGVDYVLNCILATEIESSNWQALLGRLCLIDRLLLEFPGEFYPHIVCGDVLQADAIVGRYKKLLSLLNFALLSIDNSHSMVGKLSRRVFLSSARMVARVPHVFVKLLEMLSVTSSTHYTRMRRRLMAIADEMEVAEAIQLGMEEIQSGECRHEDFLQLPVPDNSPEATENNTPNNTVQLSGKNGKGLSDKKLSAGPEDISETLTSLVVGHPVSSLTTEQPKPAVQTKGKPYSQCLNSSPSSSHSQSLFPTLLSPSNPSVSAGTVTDVSKLRPQGFIPCKIPSPSPQTQRKLSLQFQRSCSENKEPDKLSPVFTQARPLPSSHIHRPKPSRPTPNDMNKQGETSKNSMTLDLNDTSHCDGNGSNSSAVIPSEETVFTPVDEKCRLDVNAELNSSIEDLLEASMPTSDGTVTFKSEVAVLSPERAENDDTYKDDVNHNQKCKEKMEAEEEEALAIAMAMSASQDALPIIPQLQVENGEDIIIIQQDTPETLPGHTKAKHHYREDAEWLKGQQIGLGAFSSCYQAQDVGTGTLMAVKQVTYVRNTSSEQEEVVEALREEIRMMSHLNHPNIIRMLGATCEKSNYNLFIEWMAGGSVAHLLSKYGAFKESVIINYTEQLLRGLSYLHENQIIHRDVKGANLLIDSTGHRLRIADFGAAARLASKGTGAGEFQGQLLGTIAFMAPEVLRGQQYGRSCDVWSVGCVVIEMACAKPPWNAEKHSNHLALIFKIASATTAPSIPSHLSPGLRDVTLRCLELQPQDRPPSRELLKHPVFRTTW", "length": 1378, "header": "tr|A0A8V0YIE3-1|A0A8V0YIE3_CHICK Isoform 1 of Mitogen-activated protein kinase kinase kinase 1 OS=Gallus gallus OX=9031 GN=MAP3K1 PE=4 SV=1 CANONICAL=A0A8V0YIE3-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PDJ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIE3/entry#A0A1D5PDJ5-1", "sequence": { "sequence": "MENKETLRGLQKMDDRPEERMIREKLKATCMPAWKHEWLERRSRRGPVVVKPIPVKGDGSEMNKLSLEPQSEGQSSASSPTQKGRRSPSPSSSSSSSSRTVKSESPGVRRKRVSPVPFQSGRITPPRRAPSPDGFSPYSPEETSRRVNKVMRARLYLLQQIGPNSFLIGGDSPDNKYRVFIGPQTCSCGRGTFCIHLLFVMLRVFQLEPSDPMLWRKTLKNFEVESLFQKYHSRRSSRIKAPSRNTIQKFVSRMSNSHTLSSSTSTSSSENSMKDEEEQMCPICLLGMLDEESLTVCEDGCRNKLHHHCMSIWAEECRRNREPLICPLCRSKWRSHDFYSHELPSPVDSSVLHVVQQQTQQQSTIGSQRRTQDSNFNLTHYGVQQIPSAYKDLAEPWIQVFGMELVGCLFSRNWNIREMALRRLSHDVSGALLLANGESTGSSGNSNGNNTSAGALGIASGSSQATVSGDVVVESCCSVLSMVCADPVYKVYVAALKTLRAMLVYTPCHSLAERTKLQRLLKPVVETILVKCADANSRTSQLSVSTLLEMCKGQAGELAVGREILKSGSIGIGGVDYVLNCILATEIESSNWQALLGRLCLIDRLLLEFPGEFYPHIVCGDVLQADAIVGRYKKLLSLLNFALLSIDNSHSMVGKLSRRVFLSSARMVARVPHVFVKLLEMLSVTSSTHYTRMRRRLMAIADEMEVAEAIQLGMEEIQSGECRHEDFLQLPVPDNSPEATENNTPNNTVQLSGKNGKGLSDKKLSAGPEDISETLTSLVVGHPVSSLTTEQPKPAVQTKGKPYSQCLNSSPSSSHSQSLFPTLLSPSNPSVSAGTVTDVSKLRPQGFIPCKIPSPSPQTQRKLSLQFQRSCSENKEPDKLSPVFTQARPLPSSHIHRPKPSRPTPNDMNKQGETSKNSMTLDLNDTSHCDGNGSNSSAVIPSEETVFTPVDEKCRLDVNAELNSSIEDLLEASMPTSDGTVTFKSEVAVLSPERAENDDTYKDDVNHNQKCKEKMEAEEEEALAIAMAMSASQDALPIIPQLQVENGEDIIIIQQDTPETLPGHTKAKHHYREDAEWLKGQQIGLGAFSSCYQAQDVGTGTLMAVKQVTYVRNTSSEQEEVVEALREEIRMMSHLNHPNIIRMLGATCEKSNYNLFIEWMAGGSVAHLLSKYGAFKESVIINYTEQLLRGLSYLHENQIIHRDVKGANLLIDSTGHRLRIADFGAAARLASKGTGAGEFQGQLLGTIAFMAPEVLRGQQYGRSCDVWSVGCVVIEMACAKPPWNAEKHSNHLALIFKIASATTAPSIPSHLSPGLRDVTLRCLELQPQDRPPSRELLKHPVFRTTW", "length": 1346, "header": "tr|A0A1D5PDJ5-1|A0A1D5PDJ5_CHICK Computationally mapped isoform of Mitogen-activated protein kinase kinase kinase 1 OS=Gallus gallus OX=9031 GN=MAP3K1 PE=4 SV=1 CANONICAL=A0A8V0YIE3-1" }, "locus": { "chromosome": "Z", "start_pos": 18003536, "end_pos": 17982332, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031411.1", "url": "https://www.ensembl.org/id/ENSGALT00010031411.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018333.1", "url": "https://www.ensembl.org/id/ENSGALP00010018333.1" } ] } }, { "isoform_ac": "A0A8V0YHH8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIE3/entry#A0A8V0YHH8-1", "sequence": { "sequence": "MKLKSDFDSTVKFRDMENKETLRGLQKMDDRPEERMIREKLKATCMPAWKHEWLERRSRRGPVVVKPIPVKGDGSEMNKLSLEPQSEGQSSASSPTQKGRRSPSPSSSSSSSSRTVKSESPGVRRKRVSPVPFQSGRITPPRRAPSPDGFSPYSPEETSRRVNKVMRARLYLLQQIGPNSFLIGGDSPDNKYRVFIGPQTCSCGRGTFCIHLLFVMLRVFQLEPSDPMLWRKTLKNFEVESLFQKYHSRRSSRIKAPSRNTIQKFVSRMSNSHTLSSSTSTSSSENSMKDEEEQMCPICLLGMLDEESLTVCEDGCRNKLHHHCMSIWAEECRRNREPLICPLCRSKWRSHDFYSHELPSPVDSSVLHVVQQQTQQQSTIGSQRRTQDSNFNLTHYGVQQIPSAYKDLAEPWIQVFGMELVGCLFSRNWNIREMALRRLSHDVSGALLLANGESTGSSGNSNGNNTSAGALGIASGSSQATVSGDVVVESCCSVLSMVCADPVYKVYVAALKTLRAMLVYTPCHSLAERTKLQRLLKPVVETILVKCADANSRTSQLSVSTLLEMCKGQAGELAVGREILKSGSIGIGGVDYVLNCILATEIESSNWQALLGRLCLIDRLLLEFPGEFYPHIVCGDVLQADAIVGRYKKLLSLLNFALLSIDNSHSMVGKLSRRVFLSSARMVARVPHVFVKLLEMLSVTSSTHYTRMRRRLMAIADEMEVAEAIQLGMEEIQSGECRHEDFLQLPVPDNSPEATENNTPNNTVQLSGKNGKGLSDKKLSAGPEDISETLTSLVVGHPVSSLTTEQPKPAVQTKGKPYSQCLNSSPSSSHSQSLFPTLLSPSNPSVSAGTVTDVSKLRPQGFIPCKIPSPSPQTQRKLSLQFQRSCSENKEPDKLSPVFTQARPLPSSHIHRPKPSRPTPNDMNKQGETSKNSMTLDLNDTSHCDGNGSNSSAVIPSEETVFTPVDEKCRLDVNAELNSSIEDLLEASMPTSDGTVTFKSEVAVLSPERAENDDTYKDDVNHNQKCKEKMEAEEEEALAIAMAMSASQDALPIIPQLQVENGEDIIIIQQDTPETLPGHTKAKHHYREDAEWLKGQQIGLGAFSSCYQAQDVGTGTLMAVKQVTYVRNTSSEQEEVVEALREEIRMMSHLNHPNIIRMLGATCEKSNYNLFIEWMAGGSVAHLLSKYGAFKESVIINYTEQLLRGLSYLHENQIIHRDVKGANLLIDSTGHRLRIADFGAAARLASKGTGAGEFQGQLLGTIAFMAPEVLRGQQYGRSCDVWSVGCVVIEMACAKPPWNAEKHSNHLALIFKIASATTAPSIPSHLSPGLRDVTLRCLELQPQDRPPSRELLKHPVFRTTW", "length": 1361, "header": "tr|A0A8V0YHH8-1|A0A8V0YIE3_CHICK Computationally mapped isoform of Mitogen-activated protein kinase kinase kinase 1 OS=Gallus gallus OX=9031 GN=MAP3K1 PE=4 SV=1 CANONICAL=A0A8V0YIE3-1" }, "locus": { "chromosome": "Z", "start_pos": 18003536, "end_pos": 17951602, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031401.1", "url": "https://www.ensembl.org/id/ENSGALT00010031401.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018325.1", "url": "https://www.ensembl.org/id/ENSGALP00010018325.1" } ] } }, { "isoform_ac": "A0A8V0YIE3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIE3/entry#A0A8V0YIE3-1", "sequence": { "sequence": "QGSCAAAYECGFLGDLADSSTESGNLLDCSRDMENKETLRGLQKMDDRPEERMIREKLKATCMPAWKHEWLERRSRRGPVVVKPIPVKGDGSEMNKLSLEPQSEGQSSASSPTQKGRRSPSPSSSSSSSSRTVKSESPGVRRKRVSPVPFQSGRITPPRRAPSPDGFSPYSPEETSRRVNKVMRARLYLLQQIGPNSFLIGGDSPDNKYRVFIGPQTCSCGRGTFCIHLLFVMLRVFQLEPSDPMLWRKTLKNFEVESLFQKYHSRRSSRIKAPSRNTIQKFVSRMSNSHTLSSSTSTSSSENSMKDEEEQMCPICLLGMLDEESLTVCEDGCRNKLHHHCMSIWAEECRRNREPLICPLCRSKWRSHDFYSHELPSPVDSSVLHVVQQQTQQQSTIGSQRRTQDSNFNLTHYGVQQIPSAYKDLAEPWIQVFGMELVGCLFSRNWNIREMALRRLSHDVSGALLLANGESTGSSGNSNGNNTSAGALGIASGSSQATVSGDVVVESCCSVLSMVCADPVYKVYVAALKTLRAMLVYTPCHSLAERTKLQRLLKPVVETILVKCADANSRTSQLSVSTLLEMCKGQAGELAVGREILKSGSIGIGGVDYVLNCILATEIESSNWQALLGRLCLIDRLLLEFPGEFYPHIVCGDVLQADAIVGRYKKLLSLLNFALLSIDNSHSMVGKLSRRVFLSSARMVARVPHVFVKLLEMLSVTSSTHYTRMRRRLMAIADEMEVAEAIQLGMEEIQSGECRHEDFLQLPVPDNSPEATENNTPNNTVQLSGKNGKGLSDKKLSAGPEDISETLTSLVVGHPVSSLTTEQPKPAVQTKGKPYSQCLNSSPSSSHSQSLFPTLLSPSNPSVSAGTVTDVSKLRPQGFIPCKIPSPSPQTQRKLSLQFQRSCSENKEPDKLSPVFTQARPLPSSHIHRPKPSRPTPNDMNKQGETSKNSMTLDLNDTSHCDGNGSNSSAVIPSEETVFTPVDEKCRLDVNAELNSSIEDLLEASMPTSDGTVTFKSEVAVLSPERAENDDTYKDDVNHNQKCKEKMEAEEEEALAIAMAMSASQDALPIIPQLQVENGEDIIIIQQDTPETLPGHTKAKHHYREDAEWLKGQQIGLGAFSSCYQAQDVGTGTLMAVKQVTYVRNTSSEQEEVVEALREEIRMMSHLNHPNIIRMLGATCEKSNYNLFIEWMAGGSVAHLLSKYGAFKESVIINYTEQLLRGLSYLHENQIIHRDVKGANLLIDSTGHRLRIADFGAAARLASKGTGAGEFQGQLLGTIAFMAPEVLRGQQYGRSCDVWSVGCVVIEMACAKPPWNAEKHSNHLALIFKIASATTAPSIPSHLSPGLRDVTLRCLELQPQDRPPSRELLKHPVFRTTW", "length": 1378, "header": "tr|A0A8V0YIE3-1|A0A8V0YIE3_CHICK Isoform 1 of Mitogen-activated protein kinase kinase kinase 1 OS=Gallus gallus OX=9031 GN=MAP3K1 PE=4 SV=1 CANONICAL=A0A8V0YIE3-1" }, "locus": { "chromosome": "Z", "start_pos": 18003536, "end_pos": 17981631, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031385.1", "url": "https://www.ensembl.org/id/ENSGALT00010031385.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018312.1", "url": "https://www.ensembl.org/id/ENSGALP00010018312.1" } ] } }, { "isoform_ac": "A0A8V0YIF7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIE3/entry#A0A8V0YIF7-1", "sequence": { "sequence": "MEPSPAASRDMENKETLRGLQKMDDRPEERMIREKLKATCMPAWKHEWLERRSRRGPVVVKPIPVKGDGSEMNKLSLEPQSEGQSSASSPTQKGRRSPSPSSSSSSSSRTVKSESPGVRRKRVSPVPFQSGRITPPRRAPSPDGFSPYSPEETSRRVNKVMRARLYLLQQIGPNSFLIGGDSPDNKYRVFIGPQTCSCGRGTFCIHLLFVMLRVFQLEPSDPMLWRKTLKNFEVESLFQKYHSRRSSRIKAPSRNTIQKFVSRMSNSHTLSSSTSTSSSENSMKDEEEQMCPICLLGMLDEESLTVCEDGCRNKLHHHCMSIWAEECRRNREPLICPLCRSKWRSHDFYSHELPSPVDSSVLHVVQQQTQQQSTIGSQRRTQDSNFNLTHYGVQQIPSAYKDLAEPWIQVFGMELVGCLFSRNWNIREMALRRLSHDVSGALLLANGESTGSSGNSNGNNTSAGALGIASGSSQATVSGDVVVESCCSVLSMVCADPVYKVYVAALKTLRAMLVYTPCHSLAERTKLQRLLKPVVETILVKCADANSRTSQLSVSTLLEMCKGQAGELAVGREILKSGSIGIGGVDYVLNCILATEIESSNWQALLGRLCLIDRLLLEFPGEFYPHIVCGDVLQADAIVGRYKKLLSLLNFALLSIDNSHSMVGKLSRRVFLSSARMVARVPHVFVKLLEMLSVTSSTHYTRMRRRLMAIADEMEVAEAIQLGMEEIQSGECRHEDFLQLPVPDNSPEATENNTPNNTVQLSGKNGKGLSDKKLSAGPEDISETLTSLVVGHPVSSLTTEQPKPAVQTKGKPYSQCLNSSPSSSHSQSLFPTLLSPSNPSVSAGTVTDVSKLRPQGFIPCKIPSPSPQTQRKLSLQFQRSCSENKEPDKLSPVFTQARPLPSSHIHRPKPSRPTPNDMNKQGETSKNSMTLDLNDTSHCDGNGSNSSAVIPSEETVFTPVDEKCRLDVNAELNSSIEDLLEASMPTSDGTVTFKSEVAVLSPERAENDDTYKDDVNHNQKCKEKMEAEEEEALAIAMAMSASQDALPIIPQLQVENGEDIIIIQQDTPETLPGHTKAKHHYREDAEWLKGQQIGLGAFSSCYQAQDVGTGTLMAVKQVTYVRNTSSEQEEVVEALREEIRMMSHLNHPNIIRMLGATCEKSNYNLFIEWMAGGSVAHLLSKYGAFKESVIINYTEQLLRGLSYLHENQIIHRDVKGANLLIDSTGHRLRIADFGAAARLASKGTGAGEFQGQLLGTIAFMAPEVLRGQQYGRSCDVWSVGCVVIEMACAKPPWNAEKHSNHLALIFKIASATTAPSIPSHLSPGLRDVTLRCLELQPQDRPPSRELLKHPVFRTTW", "length": 1356, "header": "tr|A0A8V0YIF7-1|A0A8V0YIF7_CHICK Computationally mapped isoform of Mitogen-activated protein kinase kinase kinase 1 OS=Gallus gallus OX=9031 GN=MAP3K1 PE=4 SV=1 CANONICAL=A0A8V0YIE3-1" }, "locus": { "chromosome": "Z", "start_pos": 18003536, "end_pos": 17949564, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031405.1", "url": "https://www.ensembl.org/id/ENSGALT00010031405.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018328.1", "url": "https://www.ensembl.org/id/ENSGALP00010018328.1" } ] } }, { "isoform_ac": "A0A8V0YKF0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIE3/entry#A0A8V0YKF0-1", "sequence": { "sequence": 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"length": 1356, "header": "tr|A0A8V0YKF0-1|A0A8V0YKF0_CHICK Computationally mapped isoform of Mitogen-activated protein kinase kinase kinase 1 OS=Gallus gallus OX=9031 GN=MAP3K1 PE=4 SV=1 CANONICAL=A0A8V0YIE3-1" }, "locus": { "chromosome": "Z", "start_pos": 18003536, "end_pos": 17969906, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031392.1", "url": "https://www.ensembl.org/id/ENSGALT00010031392.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018318.1", "url": "https://www.ensembl.org/id/ENSGALP00010018318.1" } ] } }, { "isoform_ac": "A0A8V0YKF5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIE3/entry#A0A8V0YKF5-1", "sequence": { "sequence": "MENKETLRGLQKMDDRPEERMIREKLKATCMPAWKHEWLERRSRRGPVVVKPIPVKGDGSEMNKLSLEPQSEGQSSASSPTQKGRRSPSPSSSSSSSSRTVKSESPGVRRKRVSPVPFQSGRITPPRRAPSPDGFSPYSPEETSRRVNKVMRARLYLLQQIGPNSFLIGGDSPDNKYRVFIGPQTCSCGRGTFCIHLLFVMLRVFQLEPSDPMLWRKTLKNFEVESLFQKYHSRRSSRIKAPSRNTIQKFVSRMSNSHTLSSSTSTSSSENSMKDEEEQMCPICLLGMLDEESLTVCEDGCRNKLHHHCMSIWAEECRRNREPLICPLCRSKWRSHDFYSHELPSPVDSSVLHVVQQQTQQQSTIGSQRRTQDSNFNLTHYGVQQIPSAYKDLAEPWIQVFGMELVGCLFSRNWNIREMALRRLSHDVSGALLLANGESTGSSGNSNGNNTSAGALGIASGSSQATVSGDVVVESCCSVLSMVCADPVYKVYVAALKTLRAMLVYTPCHSLAERTKLQRLLKPVVETILVKCADANSRTSQLSVSTLLEMCKGQAGELAVGREILKSGSIGIGGVDYVLNCILATEIESSNWQALLGRLCLIDRLLLEFPGEFYPHIVCGDVLQADAIVGRYKKLLSLLNFALLSIDNSHSMVGKLSRRVFLSSARMVARVPHVFVKLLEMLSVTSSTHYTRMRRRLMAIADEMEVAEAIQLGMEEIQSGECRHEDFLQLPVPDNSPEATENNTPNNTVQLSGKNGKGLSDKKLSAGPEDISETLTSLVVGHPVSSLTTEQPKPAVQTKGKPYSQCLNSSPSSSHSQSLFPTLLSPSNPSVSAGTVTDVSKLRPQGFIPCKIPSPSPQTQRKLSLQFQRSCSENKEPDKLSPVFTQARPLPSSHIHRPKPSRPTPNDMNKQGETSKNSMTLDLNDTSHCDGNGSNSSAVIPSEETVFTPVDEKCRLDVNAELNSSIEDLLEASMPTSDGTVTFKSEVAVLSPERAENDDTYKDDVNHNQKCKEKMEAEEEEALAIAMAMSASQDALPIIPQLQVENGEDIIIIQQDTPETLPGHTKAKHHYREDAEWLKGQQIGLGAFSSCYQAQDVGTGTLMAVKQVTYVRNTSSEQEEVVEALREEIRMMSHLNHPNIIRMLGATCEKSNYNLFIEWMAGGSVAHLLSKYGAFKESVIINYTEQLLRGLSYLHENQIIHRDVKGANLLIDSTGHRLRIADFGAAARLASKGTGAGEFQGQLLGTIAFMAPEVLRGQQYGRSCDVWSVGCVVIEMACAKPPWNAEKHSNHLALIFKVSHLQ", "length": 1302, "header": "tr|A0A8V0YKF5-1|A0A8V0YKF5_CHICK Computationally mapped isoform of Mitogen-activated protein kinase kinase kinase 1 OS=Gallus gallus OX=9031 GN=MAP3K1 PE=4 SV=1 CANONICAL=A0A8V0YIE3-1" }, "locus": { "chromosome": "Z", "start_pos": 18002141, "end_pos": 17982332, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031400.1", "url": "https://www.ensembl.org/id/ENSGALT00010031400.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018324.1", "url": "https://www.ensembl.org/id/ENSGALP00010018324.1" } ] } }, { "isoform_ac": "F1N938-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIE3/entry#F1N938-1", "sequence": { "sequence": 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"length": 1364, "header": "tr|F1N938-1|F1N938_CHICK Computationally mapped isoform of Mitogen-activated protein kinase kinase kinase 1 OS=Gallus gallus OX=9031 GN=MAP3K1 PE=4 SV=4 CANONICAL=A0A8V0YIE3-1" }, "locus": { "chromosome": "Z", "start_pos": 18003536, "end_pos": 17982017, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031381.1", "url": "https://www.ensembl.org/id/ENSGALT00010031381.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018309.1", "url": "https://www.ensembl.org/id/ENSGALP00010018309.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-2871796", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2871796", "resource": "Reactome", "description": "FCERI mediated MAPK activation" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIE3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIE3" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIE3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIE3" } ], "pmid": "" }, { "name": "MAP kinase kinase kinase activity", "id": "GO:0004709", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004709", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIE3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIE3" } ], "pmid": "" }, { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIE3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIE3" } ], "pmid": "" }, { "name": "protein kinase binding", "id": "GO:0019901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019901", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIE3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIE3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIE3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIE3" } ], "pmid": "" }, { "name": "tight junction", "id": "GO:0070160", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070160", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIE3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIE3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "MAPK cascade", "id": "GO:0000165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000165", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIE3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIE3" } ], "pmid": "" }, { "name": "cellular response to mechanical stimulus", "id": "GO:0071260", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071260", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIE3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIE3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1145, "end_pos": 1147, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1214, "end_pos": 1216, "annotation": "n_glycosylation_sequon" }, { "start_pos": 409, "end_pos": 411, "annotation": "n_glycosylation_sequon" }, { "start_pos": 481, "end_pos": 483, "annotation": "n_glycosylation_sequon" }, { "start_pos": 482, "end_pos": 484, "annotation": "n_glycosylation_sequon" }, { "start_pos": 774, "end_pos": 776, "annotation": "n_glycosylation_sequon" }, { "start_pos": 778, "end_pos": 780, "annotation": "n_glycosylation_sequon" }, { "start_pos": 840, "end_pos": 842, "annotation": 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"snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1145, "end_pos": 1147 }, { "start_pos": 1214, "end_pos": 1216 }, { "start_pos": 409, "end_pos": 411 }, { "start_pos": 481, "end_pos": 483 }, { "start_pos": 482, "end_pos": 484 }, { "start_pos": 774, "end_pos": 776 }, { "start_pos": 778, "end_pos": 780 }, { "start_pos": 840, "end_pos": 842 }, { "start_pos": 956, "end_pos": 958 }, { "start_pos": 964, "end_pos": 966 }, { "start_pos": 967, "end_pos": 969 }, { "start_pos": 995, "end_pos": 997 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YHI4-1", "uniprot_ac": "A0A8V0YHI4", "uniprot_id": "A0A8V0YHI4_CHICK", "mass": { "chemical_mass": 86886.0, "monoisotopic_mass": 86886.0 }, "refseq": { "ac": "XP_004934598", "name": "single-minded homolog 2 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004934598" }, "gene_names": [ { "name": "SIM2", "type": "recommended", "evidence": [ { "id": "A0A8V0YHI4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHI4" } ] }, { "name": "SIM2", "type": "synonym", "evidence": [ { "id": "XP_004934598", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004934598" } ] } ], "protein_names": [ { "name": "SIM bHLH transcription factor 2", "type": "synonym", "evidence": [ { "id": "A0A8V0YHI4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHI4/entry#names_and_taxonomy" } ] }, { "name": "single-minded homolog 2 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_004934598", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004934598" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_004934598.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004934598", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004934598" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHI4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHI4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SIM2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHI4", "locus": { "chromosome": "1", "start_pos": 106949856, "end_pos": 106892133, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013099", "url": "https://www.ensembl.org/id/ENSGALG00010013099" } ] } } ], "crossref": [ { "id": "A0A8V0YHI4", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YHI4", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00130", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00130", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd19739", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd19739", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "418515", "url": "https://www.ncbi.nlm.nih.gov/gene/418515", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000014", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000014", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001610", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001610", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR010578", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010578", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011598", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011598", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013655", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013655", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013767", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013767", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035965", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035965", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036638", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036638", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:418515", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418515", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WGQPSRL", "url": "https://omabrowser.org/oma/group/WGQPSRL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YHI4", "url": "https://www.orthodb.org/?gene=A0A8V0YHI4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YQ95", "url": "https://www.orthodb.org/?gene=A0A8V0YQ95", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YQA0", "url": "https://www.orthodb.org/?gene=A0A8V0YQA0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23043", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23043", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23043:SF19", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23043:SF19", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00989", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00989", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF06621", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06621", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08447", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08447", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23171", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23171", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_004934598", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004934598", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YHI4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHI4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHI4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHI4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQ95", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ95", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQ95-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ95-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQA0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQA0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQA0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQA0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKEKSKNAAKTRREKENGEFYELAKLLPLPSAITSQLDKASIIRLTTSYLKMRAVFPEGLGDAWGQPSRIGPLDNVAKELGSHLLQTLDGFVFVVASDGKIMYISETASVHLGLSQVELTGNSIYEYIHPSDHDEMTAVLTAHQPLHPHLLQEYEIERSFFLRMKCVLAKRNAGLTCSGYKVIHCSGYLKIRQYMLDMSLYDSCYQIVGLVAVGQSLPPSAITEIKLHSNMFMFRASLDLKLIFLDSRVTELTGYEPQDLIEKTLYHHVHGCDVFHLRYAHHLLLVKGQVTTKYYRLLSKQGGWVWVQSYATIVHNSRSSRPHCIVSVNYVLTDIEYKELQLSLDQVTISKSQFSCRNSVSTSQETRKIVKPKSNKMKAKLRTTPYPQQQYSSFQTDKLECSQVGNWRSSPAVNAATIQEQNFHSENSELLYAPSYSLPFSYHYGHFPVDSHVFSSKKQMLPPKFGQSQGAPCEVARFFLSTLQTNGECQWHYANSLVPNSQSPSKNLPEQPVNIIRHNLGQSYEVPVMNRRYNQDALSDNFTSCTAPMPGSRYKEEIYDSSIMKPNKMENRIQPPHHLIKEENKLAFNRDLQEKMSINESSFSNSVANSLLPKSECFQSKALGQLSHLLPVPTVYEQTRRICMKEPKYGHISHHATSLNELDSDERMTVKLDHDSESERVMDVRPSGQVPFVLLNYHHVLAKHGTFQTSSCTATGHVGENYGYNSEEVNTFMYKNQSPSSASSPETHKETTLPHYIGTSVIIANGR", "length": 767, "header": "tr|A0A8V0YHI4-1|A0A8V0YHI4_CHICK Isoform 1 of SIM bHLH transcription factor 2 OS=Gallus gallus OX=9031 GN=SIM2 PE=4 SV=1 CANONICAL=A0A8V0YHI4-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YHI4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHI4/entry#A0A8V0YHI4-1", "sequence": { "sequence": "MKEKSKNAAKTRREKENGEFYELAKLLPLPSAITSQLDKASIIRLTTSYLKMRAVFPEGLGDAWGQPSRIGPLDNVAKELGSHLLQTLDGFVFVVASDGKIMYISETASVHLGLSQVELTGNSIYEYIHPSDHDEMTAVLTAHQPLHPHLLQEYEIERSFFLRMKCVLAKRNAGLTCSGYKVIHCSGYLKIRQYMLDMSLYDSCYQIVGLVAVGQSLPPSAITEIKLHSNMFMFRASLDLKLIFLDSRVTELTGYEPQDLIEKTLYHHVHGCDVFHLRYAHHLLLVKGQVTTKYYRLLSKQGGWVWVQSYATIVHNSRSSRPHCIVSVNYVLTDIEYKELQLSLDQVTISKSQFSCRNSVSTSQETRKIVKPKSNKMKAKLRTTPYPQQQYSSFQTDKLECSQVGNWRSSPAVNAATIQEQNFHSENSELLYAPSYSLPFSYHYGHFPVDSHVFSSKKQMLPPKFGQSQGAPCEVARFFLSTLQTNGECQWHYANSLVPNSQSPSKNLPEQPVNIIRHNLGQSYEVPVMNRRYNQDALSDNFTSCTAPMPGSRYKEEIYDSSIMKPNKMENRIQPPHHLIKEENKLAFNRDLQEKMSINESSFSNSVANSLLPKSECFQSKALGQLSHLLPVPTVYEQTRRICMKEPKYGHISHHATSLNELDSDERMTVKLDHDSESERVMDVRPSGQVPFVLLNYHHVLAKHGTFQTSSCTATGHVGENYGYNSEEVNTFMYKNQSPSSASSPETHKETTLPHYIGTSVIIANGR", "length": 767, "header": "tr|A0A8V0YHI4-1|A0A8V0YHI4_CHICK Isoform 1 of SIM bHLH transcription factor 2 OS=Gallus gallus OX=9031 GN=SIM2 PE=4 SV=1 CANONICAL=A0A8V0YHI4-1" }, "locus": { "chromosome": "1", "start_pos": 106949318, "end_pos": 106894046, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031407.1", "url": "https://www.ensembl.org/id/ENSGALT00010031407.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018330.1", "url": "https://www.ensembl.org/id/ENSGALP00010018330.1" } ] } }, { "isoform_ac": "A0A8V0YQ95-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHI4/entry#A0A8V0YQ95-1", "sequence": { "sequence": "MEMRRLRSDPQYAVLCTAQSQGSDSIVELRPVPHSKAVEIIRSKRSFRSLNSWSLGDAWGQPSRIGPLDNVAKELGSHLLQTLDGFVFVVASDGKIMYISETASVHLGLSQVELTGNSIYEYIHPSDHDEMTAVLTAHQPLHPHLLQEYEIERSFFLRMKCVLAKRNAGLTCSGYKVIHCSGYLKIRQYMLDMSLYDSCYQIVGLVAVGQSLPPSAITEIKLHSNMFMFRASLDLKLIFLDSRVTELTGYEPQDLIEKTLYHHVHGCDVFHLRYAHHLLLVKGQVTTKYYRLLSKQGGWVWVQSYATIVHNSRSSRPHCIVSVNYVLTDIEYKELQLSLDQVTISKSQFSCRNSVSTSQETRKIVKPKSNKMKAKLRTTPYPQQQYSSFQTDKLECSQVGNWRSSPAVNAATIQEQNFHSENSELLYAPSYSLPFSYHYGHFPVDSHVFSSKKQMLPPKFGQSQGAPCEVARFFLSTLQTNGECQWHYANSLVPNSQSPSKNLPEQPVNIIRHNLGQSYEVPVMNRRYNQDALSDNFTSCTAPMPGSRYKEEIYDSSIMKPNKMENRIQPPHHLIKEENKLAFNRDLQEKMSINESSFSNSVANSLLPKSECFQSKALGQLSHLLPVPTVYEQTRRICMKEPKYGHISHHATSLNELDSDERMTVKLDHDSESERVMDVRPSGQVPFVLLNYHHVLAKHGTFQTSSCTATGHVGENYGYNSEEVNTFMYKNQSPSSASSPETHKETTLPHYIGTSVIIANGR", "length": 762, "header": "tr|A0A8V0YQ95-1|A0A8V0YQ95_CHICK Computationally mapped isoform of SIM bHLH transcription factor 2 OS=Gallus gallus OX=9031 GN=SIM2 PE=4 SV=1 CANONICAL=A0A8V0YHI4-1" }, "locus": { "chromosome": "1", "start_pos": 106949318, "end_pos": 106896948, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031403.1", "url": "https://www.ensembl.org/id/ENSGALT00010031403.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018327.1", "url": "https://www.ensembl.org/id/ENSGALP00010018327.1" } ] } }, { "isoform_ac": "A0A8V0YQA0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHI4/entry#A0A8V0YQA0-1", "sequence": { "sequence": "MEQKRGPPAPPNSEAAAHAPRRSEGPGLICQCHLRLAVVAMKEKSKNAAKTRREKENGEFYELAKLLPLPSAITSQLDKASIIRLTTSYLKMRAVFPEGLGDAWGQPSRIGPLDNVAKELGSHLLQTLDGFVFVVASDGKIMYISETASVHLGLSQVELTGNSIYEYIHPSDHDEMTAVLTAHQPLHPHLLQEYEIERSFFLRMKCVLAKRNAGLTCSGYKVIHCSGYLKIRQYMLDMSLYDSCYQIVGLVAVGQSLPPSAITEIKLHSNMFMFRASLDLKLIFLDSRVTELTGYEPQDLIEKTLYHHVHGCDVFHLRYAHHLLLVKGQVTTKYYRLLSKQGGWVWVQSYATIVHNSRSSRPHCIVSVNYVLTDIEYKELQLSLDQVTISKSQFSCRNSVSTSQETRKIVKPKSNKMKAKLRTTPYPQQQYSSFQTDKLECSQVGNWRSSPAVNAATIQEQNFHSENSELLYAPSYSLPFSYHYGHFPVDSHVFSSKKQMLPPKFGQSQGAPCEVARFFLSTLQTNGECQWHYANSLVPNSQSPSKNLPEQPVNIIRHNLGQSYEVPVMNRRYNQDALSDNFTSCTAPMPGSRYKEEIYDSSIMKPNKMENRIQPPHHLIKEENKLAFNRDLQEKMSINESSFSNSVANSLLPKSECFQSKALGQLSHLLPVPTVYEQTRRICMKEPKYGHISHHATSLNELDSDERMTVKLDHDSESERVMDVRPSGQVPFVLLNYHHVLAKHGTFQTSSCTATGHVGENYGYNSEEVNTFMYKNQSPSSASSPETHKETTLPHYIGTSVIIANGR", "length": 807, "header": "tr|A0A8V0YQA0-1|A0A8V0YQA0_CHICK Computationally mapped isoform of SIM bHLH transcription factor 2 OS=Gallus gallus OX=9031 GN=SIM2 PE=4 SV=1 CANONICAL=A0A8V0YHI4-1" }, "locus": { "chromosome": "1", "start_pos": 106949318, "end_pos": 106892164, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031409.1", "url": "https://www.ensembl.org/id/ENSGALT00010031409.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018332.1", "url": "https://www.ensembl.org/id/ENSGALP00010018332.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:418515", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418515", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D4AA36-1", "protein_name": "SIM bHLH transcription factor 2", "gene_name": "Sim2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKEKSKNAAKTRREKENGEFYELAKLLPLPSAITSQLDKASIIRLTTSYLKMRAVFPEGLGDAWGQPSRTGPLDSVAKELGSHLLQTLDGFVFVVASDGKIMYISETASVHLGLSQVELTGNSIYEYIHPSDHDEMTAVLTAHPPLHHHLLQEYEIERSFFLRMKCVLAKRNAGLTCSGYKVIHCSGYLKIRQYMLDMSLYDSCYQIVGLVAVGQSLPPSAITEIKLHNNMFMFRASLDLKLIFLDSRVTELTGYEPQDLIEKTLYHHVHGCDTFHLRYAHHLLLVKGQVTTKYYRLLSKLGGWVWVQSYATVVHNSRSSRPHCIVSVNYVLTEVEYKELQLSLDQVSTSKSQESWRTTLSTSQETRKSAKPKTTKMRTKLRTNPYPSQQYSSFQMDKLECSQAGNWRTSPPTSAVAPPEQQLHSEASDLLYGPPYSLPFSYRYGHFPLDSHVFSSKKPGLPAKFGQPQGSPCEVARFFLSTLPASSECQWHYANSLMPSSPSPAKNLSESPVNAARHGLVPNYEAPAATARRFGEDPAPSSFPSCGHYREEPTLGSAKAARQASRDTARLALARATPECCAPPAPEPQAPAQLPFVLLNYHRVLARRGPLGSAAPGAPEAAGSLRPRHPGPVAASAPGAPRPHYLGASVIITNGR", "length": 656 }, "evidence": [ { "id": "A0A8V0YHI4", "url": "https://omabrowser.org/oma/group/A0A8V0YHI4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "I3LA51-1", "protein_name": "SIM bHLH transcription factor 2", "gene_name": "SIM2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MKEKSKNAAKTRREKENGEFYELAKLLPLPSAITSQLDKASIIRLTTSYLKMRAVFPEGLGDAWGQPSRAGPLDSVAKELGSHLLQTLDGFVFVVASDGKIMYISETASVHLGLSQVELTGNSIYEYIHPSDHDEMTAVLAAHQPLHHHLLQEYEIERSFFLRMKCVLAKRNAGLTCSGYKVIHCSGYLKIRQYMLDMSLYDSCYQIVGLVAVGQSLPPSAITEIKLHSNMFMFRASLDLKLIFLDSRVTELTGYEPQDLIEKTLYHHVHGCDVFHLRYAHHLLLVKGQVTTKYYRLLSKLGGWVWVQSCATVVHNSRSSRPHCIVSVNYVLTDIEYKELQLSLDQVSTSKSQDSWRTALSTSQETRKLAKPKNTKMKTKLRTNPYPPQQYSSFQMDKLDCGQLGSWRASPPASAPAPPEQQLHSEGGDLLYAPSYSLPFSYHYGHFPLDSHVFSSKKPMLPAKFGQPPGSPCEVARFLLSTLPAGSECQWHYANPLVPSGPSPAKSLSQPPANTARHSLGPNYEAPAAAARRFGEDTAPPPPSFPSCGHYREEPALGPAKAARQAARDGARLALTGPAPECCAPPAPEPPGAPAQLPFVLLNYHRVLARRGPLGGAAPAAPALACGPGVPEAAAGALRPRPPGPAAAAAAASPPGAPLPHYLGASVIITNGR", "length": 673 }, "evidence": [ { "id": "A0A8V0YHI4", "url": "https://omabrowser.org/oma/group/A0A8V0YHI4/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q14190-1", "protein_name": "Single-minded homolog 2", "gene_name": "SIM2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKEKSKNAAKTRREKENGEFYELAKLLPLPSAITSQLDKASIIRLTTSYLKMRAVFPEGLGDAWGQPSRAGPLDGVAKELGSHLLQTLDGFVFVVASDGKIMYISETASVHLGLSQVELTGNSIYEYIHPSDHDEMTAVLTAHQPLHHHLLQEYEIERSFFLRMKCVLAKRNAGLTCSGYKVIHCSGYLKIRQYMLDMSLYDSCYQIVGLVAVGQSLPPSAITEIKLYSNMFMFRASLDLKLIFLDSRVTEVTGYEPQDLIEKTLYHHVHGCDVFHLRYAHHLLLVKGQVTTKYYRLLSKRGGWVWVQSYATVVHNSRSSRPHCIVSVNYVLTEIEYKELQLSLEQVSTAKSQDSWRTALSTSQETRKLVKPKNTKMKTKLRTNPYPPQQYSSFQMDKLECGQLGNWRASPPASAAAPPELQPHSESSDLLYTPSYSLPFSYHYGHFPLDSHVFSSKKPMLPAKFGQPQGSPCEVARFFLSTLPASGECQWHYANPLVPSSSSPAKNPPEPPANTARHSLVPSYEAPAAAVRRFGEDTAPPSFPSCGHYREEPALGPAKAARQAARDGARLALARAAPECCAPPTPEAPGAPAQLPFVLLNYHRVLARRGPLGGAAPAASGLACAPGGPEAATGALRLRHPSPAATSPPGAPLPHYLGASVIITNGR", "length": 667 }, "evidence": [ { "id": "A0A8V0YHI4", "url": "https://omabrowser.org/oma/group/A0A8V0YHI4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q61079-1", "protein_name": "Single-minded homolog 2", "gene_name": "Sim2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKEKSKNAAKTRREKENGEFYELAKLLPLPSAITSQLDKASIIRLTTSYLKMRAVFPEGLGDAWGQPSRTGPLDSVAKELGSHLLQTLDGFVFVVASDGKIMYISETASVHLGLSQVELTGNSIYEYIHPSDHDEMTAVLTAHPPLHHHLLQEYEIERSFFLRMKCVLAKRNAGLTCSGYKVIHCSGYLKIRQYMLDMSLYDSCYQIVGLVAVGQSLPPSAITEIKLHSNMFMFRASLDLKLIFLDSRVTELTGYEPQDLIEKTLYHHVHGCDTFHLRYAHHLLLVKGQVTTKYYRLLSKLGGWVWVQSYATVVHNSRSSRPHCIVSVNYVLTDVEYKELQLSLDQVSTSKSQESWRTTLSTSQETRKSAKPKNTKMKTKLRTNPYPPQQYSSFQMDKLECSQVGNWRTSPPTNAVAPPEQQLHSEASDLLYGPPYSLPFSYHYGHFPLDSHVFSSKKPGLPAKFGQPQGSPCEVARFFLSTLPASSECQWHCANSLVPSSSSPAKNLSEPSPVNAARHGLVPNYEAPSAAARRFCEDPAPPSFPSCGHYREEPALGPAKAPRQASRDAARLALARAPPECCAPPAPEPQAPAQLPFVLLNYHRVLARRGPLGSAAPGAPEAAGSLRPRHPGPVAASAPGAPRPHYLGASVIITNGR", "length": 657 }, "evidence": [ { "id": "A0A8V0YHI4", "url": "https://omabrowser.org/oma/group/A0A8V0YHI4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 6, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHI4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHI4" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHI4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHI4" } ], "pmid": "" }, { "name": "protein dimerization activity", "id": "GO:0046983", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046983", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHI4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHI4" } ], "pmid": "" }, { "name": "protein heterodimerization activity", "id": "GO:0046982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046982", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHI4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHI4" } ], "pmid": "" }, { "name": "RNA polymerase II transcription regulatory region sequence-specific DNA binding", "id": "GO:0000977", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000977", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHI4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHI4" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHI4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHI4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHI4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHI4" } ], "pmid": "" }, { "name": "nuclear body", "id": "GO:0016604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016604", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHI4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHI4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHI4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHI4" } ], "pmid": "" }, { "name": "nervous system development", "id": "GO:0007399", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007399", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHI4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHI4" } ], "pmid": "" }, { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHI4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHI4" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHI4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHI4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 541, "end_pos": 543, "annotation": "n_glycosylation_sequon" }, { "start_pos": 599, "end_pos": 601, "annotation": "n_glycosylation_sequon" }, { "start_pos": 736, "end_pos": 738, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YHI4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHI4" }, { "id": "PS50888", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50888" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "BHLH", "eco_id": "ECO_0000259", "start_pos": 1, "end_pos": 53, "start_aa": "Met", "end_aa": "Arg", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0YHI4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHI4" }, { "id": "PS50112", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50112" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PAS", "eco_id": "ECO_0000259", "start_pos": 77, "end_pos": 140, "start_aa": "Ala", "end_aa": "Leu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0YHI4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHI4" }, { "id": "PS51302", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51302" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Single-minded C-terminal", "eco_id": "ECO_0000259", "start_pos": 336, "end_pos": 767, "start_aa": "Glu", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 541, "end_pos": 543 }, { "start_pos": 599, "end_pos": 601 }, { "start_pos": 736, "end_pos": 738 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YHI8-1", "uniprot_ac": "A0A8V0YHI8", "uniprot_id": "A0A8V0YHI8_CHICK", "mass": { "chemical_mass": 177236.0, "monoisotopic_mass": 177236.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Uncharacterized protein", "type": "synonym", "evidence": [ { "id": "A0A8V0YHI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHI8/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHI8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHI8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHI8", "locus": {} } ], "crossref": [ { "id": "IPR032771", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032771", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR36866", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR36866", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR36866:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR36866:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15030", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15030", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0Y932", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y932", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y932-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y932-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YAL9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAL9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YAL9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAL9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHI8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHI8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHI8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHI8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MESDSVLRNRMKELELSHKTLLVMIDQLNMKVHHFENANVRVKGKLREVWEELLTLVENQEKSEKKQKERLHWLQKQLKTKENELKSQSEYFEHYKQRQKQQTAVLKKRECYLRGEVFRLEKQVLDLSDHIALLTSELGEGMAQCLHKKLESASKSMQSYKLSNMQLTELKNSIGNVEHDMKSHFESFQKNLKFLRDKEEDNRRERADLLTQLQCSQDAEDFLRRKLEEACHHVYSLKLSEIKLQEQVNKLLDENKDLKYQARVRLKKKEEKNSQLTRPESTDNSPDLNRDLHQQDVQNQKRGAISDQWRNTAAKTPVVLLHALEYETPEYSCDGPKQTKKLRELRPLLEHSSSTFANAAEELGLAEIRLVTLGTKSTGASEDSFTVFRCTPSYPTARLLPPCSEKVTNSETSKGNRDEEYFSFLKEQAIYLPAKMFPVSVVEDLMRNKPNIIFLKPESYKVETVTTVKKVRSLDFSGANTSLCLGGPCVVSEEGFSDKAPTALCRKTPCSVTENFASSLQKCRVEKHQQNKLILPKSIRKNKSSDKSVRDRKYHQKIFRSRIKGEEIQNEKSQVQQVTSAFGENSNVLNQSGLIKPEKQGIEAEDKQGSPQGVHKISVDVKDFQVHFRGSPEQVEKQGRLSEICISDVMRVCKDGDMMKMEEEEKKPQKTTDQINPSRNTGLEEKKVQFLKLHESNEKNFSCQEIAAENTQYAYPQKCLWSEEEGYPLNILSPMQKGLVCLSKQFLPENNFSEYFCHLSPPAVVHEHNMKAHALEKLVAMCSQRIFQLMQENENYFKKVRMLQEENERCVQKMCALEEDMNAYFQYALDVDEDNIVSFQNLLNENETVGKCYKMSEGNTKSPGSIFAKTISKNLSYVEDKSRDLGKDSLTAESDELPKSALPLDRKKIRYFQLLSDLKEERRRCFKEIAKLLQDKENYIAKYNELTQEREGNLKRISLLEGEKENLLGSLAEIKCEQDKYRALVSELQECKSSCYQTISDLQEEKCVLKGAIDQIKKENAERLGEFQKANADFILENNKLKELMYSLGFTYEDLRKENSLGIKEKVVKIKEENKSQQYGAKPMTVETACSVTQTEEEGRDPSIYFHRKEGSRSESYSAMKEQVERTKEELKTQQKELEKSKKEAQKWYRELGFAETRYEEIKTHLTHVLSELDCLKQEAGDKTLGKQHCRFMPMYTMKDAQEMEENKISSKRLQQQVLTLKAQLRDQTALQNQFHDLQNKVELLQAQLCEKTKELQERKSEVMLTLAPLKAKLACLTRKCQERNSFITRMHGEFHRRGFNNSMFDEEVRRLVNDIALAEYTATFATTCNQEMLPSSTDISEVSAQSENHEALVRVSRTSGSIPANSLQEADGIHSSHITPNMHTSSSVKLTSPERIIALHRELRQNYHRNCQLPSFVSSNTSSKADPNLSVTHEETPWPPLQKMKNTLELSERDWSMQGTDCLSKWDDVFGGQIGNQHASAIPQGIKQKDVITNNAWLSREKTDGSTSATTAKSSLSDMLSASNKGRNPVGRNQLHGKE", "length": 1540, "header": "tr|A0A8V0YHI8-1|A0A8V0YHI8_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0YHI8-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Y932-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHI8/entry#A0A8V0Y932-1", "sequence": { "sequence": "MVGDLHQQDVQNQKRGAISDQWRNTAAKTPVVLLHALEYETPEYSCDGPKQTKKLRELRPLLEHSSSTFANAAEELGLAEIRLVTLGTKSTGASEDSFTVFRCTPSYPTARLLPPCSEKVTNSETSKGNRDEEYFSFLKEQAIYLPAKMFPVSVVEDLMRNKPNIIFLKPESYKVETVTTVKKVRSLDFSGANTSLCLGGPCVVSEEGFSDKAPTALCRKTPCSVTENFASSLQKCRVEKHQQNKLILPKSIRKNKSSDKSVRDRKYHQKIFRSRIKGEEIQNEKSQVQQVTSAFGENSNVLNQSGLIKPEKQGIEAEDKQGSPQGVHKISVDVKDFQVHFRGSPEQVEKQGRLSEICISDVMRVCKDGDMMKMEEEEKKPQKTTDQINPSRNTGLEEKKVQFLKLHESNEKNFSCQEIAAENTQYAYPQKCLWSEEEGYPLNILSPMQKGLVCLSKQFLPENNFSEYFCHLSPPAVVHEHNMKAHALEKLVAMCSQRIFQLMQENENYFKKVRMLQEENERCVQKMCALEEDMNAYFQYALDVDEDNIVSFQNLLNENETVGKCYKMSEGNTKSPGSIFAKTISKNLSYVEDKSRDLGKDSLTAESDELPKSALPLDRKKIRYFQLLSDLKEERRRCFKEIAKLLQDKENYIAKYNELTQEREGNLKRISLLEGEKENLLGSLAEIKCEQDKYRALVSELQECKSSCYQTISDLQEEKCVLKGAIDQIKKENAERLGEFQKANADFILENNKLKELMYSLGFTYEDLRKENSLGIKEKVVKIKEENKSQQYGAKPMTVETACSVTQTEEEGRDPSIYFHRKEGSRSESYSAMKEQVERTKEELKTQQKELEKSKKEAQKWYRELGFAETRYEEIKTHLTHVLSELDCLKQEAGDKTLGKQHCRFMPMYTMKDAQEMEENKISSKRLQQQVLTLKAQLRDQTALQNQFHDLQNKVELLQAQLCEKAKLACLTRKCQERNSFITRMHGEFHRRGFNNSMFDEEVRRLVNDIALAEYTATFATTCNQEMLPSSTDISEVSAQSENHEALVRVSRTSGSIPANSLQEADGIHSSHITPNMHTSSSVKLTSPERIIALHRELRQNYHRNCQLPSFVSSNTSSKADPNLSVTHEETPWPPLQKMKNTLELSERDWSMQGTDCLSKWDDVFGGQIGNQHASAIPQGIKQKDVITNNAWLSREKTDGSTSATTAKSSLSDMLSASNKGRNPVGRNQLHGKE", "length": 1234, "header": "tr|A0A8V0Y932-1|A0A8V0Y932_CHICK Computationally mapped isoform of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0YHI8-1" }, "locus": { "chromosome": "4", "start_pos": 78851395, "end_pos": 78827187, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027187.1", "url": "https://www.ensembl.org/id/ENSGALT00010027187.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015481.1", "url": "https://www.ensembl.org/id/ENSGALP00010015481.1" } ] } }, { "isoform_ac": "A0A8V0YAL9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHI8/entry#A0A8V0YAL9-1", "sequence": { "sequence": "MESDSVLRNRMKELELSHKTLLVMIDQLNMKVHHFENANVRVKGKLREVWEELLTLVENQEKSEKKQKERLHWLQKQLKTKENELKSQSEYFEHYKQRQKQQTAVLKKRECYLRGEVFRLEKQVLDLSDHIALLTSELGEGMAQCLHKKLESASKSMQSYKLSNMQLTELKNSIGNVEHDMKSHFESFQKNLKFLRDKEEDNRRERADLLTQLQCSQDAEDFLRRKLEEACHHVYSLKLSEIKLQEQVNKLLDENKDLKYQARVRLKKKEEKNSQLTRPESTDNSPDLNRDLHQQDVQNQKRGAISDQWRNTAAKTPVVLLHALEYETPEYSCDGPKQTKKLRELRPLLEHSSSTFANAAEELGLAEIRLVTLGTKSTGASEDSFTVFRCTPSYPTARLLPPCSEKVTNSETSKGNRDEEYFSFLKEQAIYLPAKMFPVSVVEDLMRNKPNIIFLKPESYKVETVTTVKKVRSLDFSGANTSLCLGGPCVVSEEGFSDKAPTALCRKTPCSVTENFASSLQKCRVEKHQQNKLILPKSIRKNKSSDKSVRDRKYHQKIFRSRIKGEEIQNEKSQVQQVTSAFGENSNVLNQSGLIKPEKQGIEAEDKQGSPQGVHKISVDVKDFQVHFRGSPEQVEKQGRLSEICISDVMRVCKDGDMMKMEEEEKKPQKTTDQINPSRNTGLEEKKVQFLKLHESNEKNFSCQEIAAENTQYAYPQKCLWSEEEGYPLNILSPMQKGLVCLSKQFLPENNFSEYFCHLSPPAVVHEHNMKAHALEKLVAMCSQRIFQLMQENENYFKKVRMLQEENERCVQKMCALEEDMNAYFQYALDVDEDNIVSFQNLLNENETVGKCYKMSEGNTKSPGSIFAKTISKNLSYVEDKSRDLGKDSLTAESDELPKSALPLDRKKIRYFQLLSDLKEERRRCFKEIAKLLQDKENYIAKYNELTQEREGNLKRISLLEGEKENLLGSLAEIKCEQDKYRALVSELQECKSSCYQTISDLQEEKCVLKGAIDQIKKENAERLGEFQKANADFILENNKLKELMYSLGFTYEDLRKENSLGIKEKVVKIKEENKSQQYGAKPMTVETACSVTQTEEEGRDPSIYFHRKEGSRSESYSAMKEQVERTKEELKTQQKELEKSKKEAQKWYRELGFAETRYEEIKTHLTHVLSELDCLKQEAGDKTLGKQHCRFMPMYTMKDAQEMEENKISSKRLQQQVLTLKAQLRDQTALQNQFHDLQNKVELLQAQLCEKAKLACLTRKCQERNSFITRMHGEFHRRGFNNSMFDEEVRRLVNDIALAEYTATFATTCNQEMLPSSTDISEVSAQSENHEALVRVSRTSGSIPANSLQEADGIHSSHITPNMHTSSSVKLTSPERIIALHRELRQNYHRNCQLPSFVSSNTSSKADPNLSVTHEETPWPPLQKMKNTLELSERDWSMQGTDCLSKWDDVFGGQIGNQHASAIPQGIKQKDVITNNAWLSREKTDGSTSATTAKSSLSDMLSASNKGRNPVGRNQLHGKE", "length": 1521, "header": "tr|A0A8V0YAL9-1|A0A8V0YAL9_CHICK Computationally mapped isoform of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0YHI8-1" }, "locus": { "chromosome": "4", "start_pos": 78854503, "end_pos": 78827187, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027194.1", "url": "https://www.ensembl.org/id/ENSGALT00010027194.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015484.1", "url": "https://www.ensembl.org/id/ENSGALP00010015484.1" } ] } }, { "isoform_ac": "A0A8V0YHI8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHI8/entry#A0A8V0YHI8-1", "sequence": { "sequence": "MESDSVLRNRMKELELSHKTLLVMIDQLNMKVHHFENANVRVKGKLREVWEELLTLVENQEKSEKKQKERLHWLQKQLKTKENELKSQSEYFEHYKQRQKQQTAVLKKRECYLRGEVFRLEKQVLDLSDHIALLTSELGEGMAQCLHKKLESASKSMQSYKLSNMQLTELKNSIGNVEHDMKSHFESFQKNLKFLRDKEEDNRRERADLLTQLQCSQDAEDFLRRKLEEACHHVYSLKLSEIKLQEQVNKLLDENKDLKYQARVRLKKKEEKNSQLTRPESTDNSPDLNRDLHQQDVQNQKRGAISDQWRNTAAKTPVVLLHALEYETPEYSCDGPKQTKKLRELRPLLEHSSSTFANAAEELGLAEIRLVTLGTKSTGASEDSFTVFRCTPSYPTARLLPPCSEKVTNSETSKGNRDEEYFSFLKEQAIYLPAKMFPVSVVEDLMRNKPNIIFLKPESYKVETVTTVKKVRSLDFSGANTSLCLGGPCVVSEEGFSDKAPTALCRKTPCSVTENFASSLQKCRVEKHQQNKLILPKSIRKNKSSDKSVRDRKYHQKIFRSRIKGEEIQNEKSQVQQVTSAFGENSNVLNQSGLIKPEKQGIEAEDKQGSPQGVHKISVDVKDFQVHFRGSPEQVEKQGRLSEICISDVMRVCKDGDMMKMEEEEKKPQKTTDQINPSRNTGLEEKKVQFLKLHESNEKNFSCQEIAAENTQYAYPQKCLWSEEEGYPLNILSPMQKGLVCLSKQFLPENNFSEYFCHLSPPAVVHEHNMKAHALEKLVAMCSQRIFQLMQENENYFKKVRMLQEENERCVQKMCALEEDMNAYFQYALDVDEDNIVSFQNLLNENETVGKCYKMSEGNTKSPGSIFAKTISKNLSYVEDKSRDLGKDSLTAESDELPKSALPLDRKKIRYFQLLSDLKEERRRCFKEIAKLLQDKENYIAKYNELTQEREGNLKRISLLEGEKENLLGSLAEIKCEQDKYRALVSELQECKSSCYQTISDLQEEKCVLKGAIDQIKKENAERLGEFQKANADFILENNKLKELMYSLGFTYEDLRKENSLGIKEKVVKIKEENKSQQYGAKPMTVETACSVTQTEEEGRDPSIYFHRKEGSRSESYSAMKEQVERTKEELKTQQKELEKSKKEAQKWYRELGFAETRYEEIKTHLTHVLSELDCLKQEAGDKTLGKQHCRFMPMYTMKDAQEMEENKISSKRLQQQVLTLKAQLRDQTALQNQFHDLQNKVELLQAQLCEKTKELQERKSEVMLTLAPLKAKLACLTRKCQERNSFITRMHGEFHRRGFNNSMFDEEVRRLVNDIALAEYTATFATTCNQEMLPSSTDISEVSAQSENHEALVRVSRTSGSIPANSLQEADGIHSSHITPNMHTSSSVKLTSPERIIALHRELRQNYHRNCQLPSFVSSNTSSKADPNLSVTHEETPWPPLQKMKNTLELSERDWSMQGTDCLSKWDDVFGGQIGNQHASAIPQGIKQKDVITNNAWLSREKTDGSTSATTAKSSLSDMLSASNKGRNPVGRNQLHGKE", "length": 1540, "header": "tr|A0A8V0YHI8-1|A0A8V0YHI8_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0YHI8-1" }, "locus": { "chromosome": "4", "start_pos": 78854503, "end_pos": 78827187, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027191.1", "url": "https://www.ensembl.org/id/ENSGALT00010027191.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015483.1", "url": "https://www.ensembl.org/id/ENSGALP00010015483.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 1074, "end_pos": 1076, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1301, "end_pos": 1303, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1421, "end_pos": 1423, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1429, "end_pos": 1431, "annotation": "n_glycosylation_sequon" }, { "start_pos": 480, "end_pos": 482, "annotation": "n_glycosylation_sequon" }, { "start_pos": 542, "end_pos": 544, "annotation": "n_glycosylation_sequon" }, { "start_pos": 590, "end_pos": 592, "annotation": "n_glycosylation_sequon" }, { "start_pos": 700, "end_pos": 702, "annotation": "n_glycosylation_sequon" }, { "start_pos": 751, "end_pos": 753, "annotation": "n_glycosylation_sequon" }, { "start_pos": 846, "end_pos": 848, "annotation": "n_glycosylation_sequon" }, { "start_pos": 874, "end_pos": 876, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1074, "end_pos": 1076 }, { "start_pos": 1301, "end_pos": 1303 }, { "start_pos": 1421, "end_pos": 1423 }, { "start_pos": 1429, "end_pos": 1431 }, { "start_pos": 480, "end_pos": 482 }, { "start_pos": 542, "end_pos": 544 }, { "start_pos": 590, "end_pos": 592 }, { "start_pos": 700, "end_pos": 702 }, { "start_pos": 751, "end_pos": 753 }, { "start_pos": 846, "end_pos": 848 }, { "start_pos": 874, "end_pos": 876 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YHJ0-1", "uniprot_ac": "A0A8V0YHJ0", "uniprot_id": "A0A8V0YHJ0_CHICK", "mass": { "chemical_mass": 22406.0, "monoisotopic_mass": 22406.0 }, "refseq": { "ac": "XP_417759", "name": "uncharacterized protein C1orf109 homolog isoform X4", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_417759" }, "gene_names": [ { "name": "C23H1ORF109", "type": "recommended", "evidence": [ { "id": "A0A8V0YHJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHJ0" } ] }, { "name": "C23H1ORF109", "type": "synonym", "evidence": [ { "id": "XP_417759", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_417759" } ] } ], "protein_names": [ { "name": "AFG2 interacting ribosome maturation factor", "type": "synonym", "evidence": [ { "id": "A0A8V0YHJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHJ0/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein C1orf109 homolog isoform X4", "type": "synonym", "evidence": [ { "id": "XP_417759", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_417759" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052554.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_417759.5. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_417759", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_417759" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHJ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHJ0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "C23H1ORF109", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHJ0", "locus": {} } ], "crossref": [ { "id": "A0A8V0YHJ0", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YHJ0", "database": "AlphaFoldDB", "categories": [] }, { "id": "419612", "url": "https://www.ncbi.nlm.nih.gov/gene/419612", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR029159", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029159", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:419612", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419612", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YHJ0", "url": "https://www.orthodb.org/?gene=A0A8V0YHJ0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16234", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16234", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16234:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16234:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15011", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15011", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_417759", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_417759", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YHJ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHJ0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHJ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHJ0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAMAAMVEALREWAVAAARRDAAWRAAVAACAPLLASLAGLAAQMRAAQRLAWDGTPLGAFSELRERLWRKQRGAAEALLEELCERREELRAVRDAVGAGAAAVLRLYEERAAELSLTEVLRRGPRCPSLADALEGLQDVERYYRHMYLEIRLFLLLISCDSLADMEALQQAWERILERYGEETVQDAFLKISLFLDNQ", "length": 200, "header": "tr|A0A8V0YHJ0-1|A0A8V0YHJ0_CHICK Isoform 1 of AFG2 interacting ribosome maturation factor OS=Gallus gallus OX=9031 GN=C23H1ORF109 PE=4 SV=1 CANONICAL=A0A8V0YHJ0-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YHJ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHJ0/entry#A0A8V0YHJ0-1", "sequence": { "sequence": 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YHJ6-1", "uniprot_ac": "A0A8V0YHJ6", "uniprot_id": "A0A8V0YHJ6_CHICK", "mass": { "chemical_mass": 101265.0, "monoisotopic_mass": 101265.0 }, "refseq": { "ac": "XP_025010804", "name": "SH3 and PX domain-containing protein 2B isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025010804" }, "gene_names": [ { "name": "SH3PXD2B", "type": "recommended", "evidence": [ { "id": "A0A8V0YHJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHJ6" } ] }, { "name": "SH3PXD2B", "type": "synonym", "evidence": [ { "id": "XP_025010804", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025010804" } ] } ], "protein_names": [ { "name": "SH3 and PX domain-containing protein 2B", "type": "recommended", "evidence": [ { "id": "A0A8V0YHJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHJ6/entry#names_and_taxonomy" } ] }, { "name": "Factor for adipocyte differentiation 49", "type": "synonym", "evidence": [ { "id": "A0A8V0YHJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHJ6/entry#names_and_taxonomy" } ] }, { "name": "SH3 and PX domain-containing protein 2B isoform X1", "type": "synonym", "evidence": [ { "id": "XP_025010804", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025010804" } ] }, { "name": "Tyrosine kinase substrate with four SH3 domains", "type": "synonym", "evidence": [ { "id": "A0A8V0YHJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHJ6/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052544.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_025010804.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_025010804", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025010804" } ] }, { "annotation": "Adapter protein involved in invadopodia and podosome formation and extracellular matrix degradation. Binds matrix metalloproteinases (ADAMs), NADPH oxidases (NOXs) and phosphoinositides. Acts as an organizer protein that allows NOX1- or NOX3-dependent reactive oxygen species (ROS) generation and ROS localization. Plays a role in mitotic clonal expansion during the immediate early stage of adipocyte differentiation.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHJ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHJ6#function" }, { "database": "UniProtKB", "id": "ARBA00058103", "url": "https://www.uniprot.org/uniprotkb/ARBA00058103#function" }, { "database": "UniProtKB", "id": "A0A8V0YMC2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMC2#function" }, { "database": "UniProtKB", "id": "A0A8V0Y965", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y965#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHJ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHJ6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SH3PXD2B", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHJ6", "locus": { "chromosome": "13", "start_pos": 8531666, "end_pos": 8466393, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012382", "url": "https://www.ensembl.org/id/ENSGALG00010012382" } ] } } ], "crossref": [ { "id": "A0A8V0YHJ6", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YHJ6", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd06888", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06888", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd12018", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12018", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd12075", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12075", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd12076", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12076", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd12078", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12078", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "427625", "url": "https://www.ncbi.nlm.nih.gov/gene/427625", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001655", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001655", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001683", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001683", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035477", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035477", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035478", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035478", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035479", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035479", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035480", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035480", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036028", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036028", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036871", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036871", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037961", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037961", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051228", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051228", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:427625", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427625", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PMIPTKH", "url": "https://omabrowser.org/oma/group/PMIPTKH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y965", "url": "https://www.orthodb.org/?gene=A0A8V0Y965", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YHJ6", "url": "https://www.orthodb.org/?gene=A0A8V0YHJ6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YMC2", "url": "https://www.orthodb.org/?gene=A0A8V0YMC2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15706", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15706", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15706:SF26", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15706:SF26", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00018", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00018", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00787", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00787", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07653", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07653", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_025010804", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025010804", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Y965", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y965", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y965-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y965-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHJ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHJ6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHJ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHJ6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YMC2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMC2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YMC2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMC2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPRRSIAEVKVLDVQKRRIPNKHYVYIIKVTWSNGSTEVIYRRYSKFFDLQMQMLDKFPMEGGQKDPKQRIIPFLPGKILFRRSHIRDVAVKRLIPIDEYCKALIQLPPYISQCEEVLQFFETRPDDLTPPKEEPIGKKKSGFIQRTTSFLQRGADSASVDPLVLEQYVVVANYQKQESSEISLCVGQLVDIIEKNESGWWFVSTSEEQGWVPATCLEAQDGVQDELSMQPDEVPWRYWSLPRHVGRRRTLGDLYTSGWGQEEKYTVIYPYTARDQDEMNLDKGAVVVVIQKNLEGWWKIRYQGQEGWAPASYLKKGNGEMFSQKLGSGSSAHSCALDLDGISRQQAVTSREKDGRFDNRPLPNADIRRKSPKMRQRPPPRRDLTIPRGLNLPKPPVPPQVEEEYYTIADFQTTIPDGISFQAGMKVEVIEKNLSGWWYIQIEEKEGWAPATFIDKYKKTSNASRPNFLAPLPSEMAQLRLGDAAAESSATEEATGPCRPLPEAPPNGMDCGMKRAKDWKGKEATESGDLAFTCGYEEISDRDVEEKPSLPPRKESIIKSEGELLERQRPPPKPPGMILPMIPPKQSAAPKDSKKPELKPEKGKLFQLKNEMGLECGHKVSAKEVKKPNLRPIVKPTKPKAEPVEDKTEPITQNPFLKSRPQIKPKPATAPRTDPPPADDKLDICSLRSKLRPAKCPEKPPEQDTAASESSCSTPAVAPEASGRFQERPSVESKALPKSPPGPAVAPAAREPTPQRPVVPPRRPPPPKKTTSPVAGPVPEARASPLPGRPMLVPPKARPFLSAAIQDEAKVKSSVGPKVISKAVERGEGRERTSAPFSNPDVSKEALYVAVADFEGDEETNSFREGTLFEVREKNSSGWWFCKVLTGGPCWEGWIPSNYLRKKP", "length": 904, "header": "tr|A0A8V0YHJ6-1|A0A8V0YHJ6_CHICK Isoform 1 of SH3 and PX domain-containing protein 2B OS=Gallus gallus OX=9031 GN=SH3PXD2B PE=1 SV=1 CANONICAL=A0A8V0YHJ6-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Y965-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHJ6/entry#A0A8V0Y965-1", "sequence": { "sequence": "MPRRSIAEVKVLDVQKRRIPNKHYVYIIKVTWSNGSTEVIYRRYSKFFDLQMQMLDKFPMEGGQKDPKQRIIPFLPGKILFRRSHIRDVAVKRLIPIDEYCKALIQLPPYISQCEEVLQFFETRPDDLTPPKEEPIGKKKSGADSASVDPLVLEQYVVVANYQKQESSEISLCVGQLVDIIEKNESGWWFVSTSEEQGWVPATCLEAQDGVQDELSMQPDEVPWRYWSLPRHVGRRRTLGDLYTSGWGQEEKYTVIYPYTARDQDEMNLDKGAVVVVIQKNLEGWWKIRYQGQEGWAPASYLKKGNGEMFSQKLGSGSSAHSCALDLDGISRQQAVTSREKDGRFDNRPLPNADIRRKSPKMRQRPPPRRDLTIPRGLNLPKPPVPPQVEEEYYTIADFQTTIPDGISFQAGMKVEVIEKNLSGWWYIQIEEKEGWAPATFIDKYKKTSNASRPNFLAPLPSEMAQLRLGDAAAESSATEEATGPCRPLPEAPPNGMDCGMKRAKDWKGKEATESGDLAFTCGYEEISDRDVEEKPSLPPRKESIIKSEGELLERQRPPPKPPGMILPMIPPKQSAAPKDSKKPELKPEKGKLFQLKNEMGLECGHKVSAKEVKKPNLRPIVKPTKPKAEPVEDKTEPITQNPFLKSRPQIKPKPATAPRTDPPPADDKLDICSLRSKLRPAKCPEKPPEQDTAASESSCSTPAVAPEASGRFQERPSVESKALPKSPPGPAVAPAAREPTPQRPVVPPRRPPPPKKTTSPVAGPVPEARASPLPGRPMLVPPKARPFLSAAIQDEAKVKSSVGPKVISKAVERGEGRERTSAPFSNPDVSKEALYVAVADFEGDEETNSFREGTLFEVREKNSSGWWFCKVLTGGPCWEGWIPSNYLRKKP", "length": 892, "header": "tr|A0A8V0Y965-1|A0A8V0Y965_CHICK Computationally mapped isoform of SH3 and PX domain-containing protein 2B OS=Gallus gallus OX=9031 GN=SH3PXD2B PE=1 SV=1 CANONICAL=A0A8V0YHJ6-1" }, "locus": { "chromosome": "13", "start_pos": 8530662, "end_pos": 8466511, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029648.1", "url": "https://www.ensembl.org/id/ENSGALT00010029648.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017252.1", "url": "https://www.ensembl.org/id/ENSGALP00010017252.1" } ] } }, { "isoform_ac": "A0A8V0YHJ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHJ6/entry#A0A8V0YHJ6-1", "sequence": { "sequence": "MPRRSIAEVKVLDVQKRRIPNKHYVYIIKVTWSNGSTEVIYRRYSKFFDLQMQMLDKFPMEGGQKDPKQRIIPFLPGKILFRRSHIRDVAVKRLIPIDEYCKALIQLPPYISQCEEVLQFFETRPDDLTPPKEEPIGKKKSGFIQRTTSFLQRGADSASVDPLVLEQYVVVANYQKQESSEISLCVGQLVDIIEKNESGWWFVSTSEEQGWVPATCLEAQDGVQDELSMQPDEVPWRYWSLPRHVGRRRTLGDLYTSGWGQEEKYTVIYPYTARDQDEMNLDKGAVVVVIQKNLEGWWKIRYQGQEGWAPASYLKKGNGEMFSQKLGSGSSAHSCALDLDGISRQQAVTSREKDGRFDNRPLPNADIRRKSPKMRQRPPPRRDLTIPRGLNLPKPPVPPQVEEEYYTIADFQTTIPDGISFQAGMKVEVIEKNLSGWWYIQIEEKEGWAPATFIDKYKKTSNASRPNFLAPLPSEMAQLRLGDAAAESSATEEATGPCRPLPEAPPNGMDCGMKRAKDWKGKEATESGDLAFTCGYEEISDRDVEEKPSLPPRKESIIKSEGELLERQRPPPKPPGMILPMIPPKQSAAPKDSKKPELKPEKGKLFQLKNEMGLECGHKVSAKEVKKPNLRPIVKPTKPKAEPVEDKTEPITQNPFLKSRPQIKPKPATAPRTDPPPADDKLDICSLRSKLRPAKCPEKPPEQDTAASESSCSTPAVAPEASGRFQERPSVESKALPKSPPGPAVAPAAREPTPQRPVVPPRRPPPPKKTTSPVAGPVPEARASPLPGRPMLVPPKARPFLSAAIQDEAKVKSSVGPKVISKAVERGEGRERTSAPFSNPDVSKEALYVAVADFEGDEETNSFREGTLFEVREKNSSGWWFCKVLTGGPCWEGWIPSNYLRKKP", "length": 904, "header": "tr|A0A8V0YHJ6-1|A0A8V0YHJ6_CHICK Isoform 1 of SH3 and PX domain-containing protein 2B OS=Gallus gallus OX=9031 GN=SH3PXD2B PE=1 SV=1 CANONICAL=A0A8V0YHJ6-1" }, "locus": { "chromosome": "13", "start_pos": 8530662, "end_pos": 8466511, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029646.1", "url": "https://www.ensembl.org/id/ENSGALT00010029646.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017250.1", "url": "https://www.ensembl.org/id/ENSGALP00010017250.1" } ] } }, { "isoform_ac": "A0A8V0YMC2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHJ6/entry#A0A8V0YMC2-1", "sequence": { "sequence": "MPRRSIAEVKVLDVQKRRIPNKHYVYIIKVTWSNGSTEVIYRRYSKFFDLQMQMLDKFPMEGGQKDPKQRIIPFLPGKILFRRSHIRDVAVKRLIPIDEYCKALIQLPPYISQCEEVLQFFETRPDDLTPPKEEPIGKKKSGADSASVDPLVLEQYVVVANYQKQESSEISLCVGQLVDIIEKNESGWWFVSTSEEQGWVPATCLEAQDGVQDELSMQPDEEEKYTVIYPYTARDQDEMNLDKGAVVVVIQKNLEGWWKIRYQGQEGWAPASYLKKGNGEMFSQKLGSGSSAHSCALDLDGISRQQAVTSREKDGRFDNRPLPNADIRRSKWQVGRMLVVAGCQRSLSCMLPESPKMRQRPPPRRDLTIPRGLNLPKPPVPPQVEEEYYTIADFQTTIPDGISFQAGMKVEVIEKNLSGWWYIQIEEKEGWAPATFIDKYKKTSNASRPNFLAPLPSEMAQLRLGDAAAESSATEEATGPCRPLPEAPPNGMDCGMKRAKDWKGKEATESGDLAFTCGYEEISDRDVEEKPSLPPRKESIIKSEGELLERQRPPPKPPGMILPMIPPKQSAAPKDSKKPELKPEKGKLFQLKNEMGLECGHKVSAKEVKKPNLRPIVKPTKPKAEPVEDKTEPITQNPFLKSRPQIKPKPATAPRTDPPPADDKLDICSLRSKLRPAKCPEKPPEQDTAASESSCSTPAVAPEASGRFQERPSVESKALPKSPPGPAVAPAAREPTPQRPVVPPRRPPPPKKTTSPVAGPVPEARASPLPGRPMLVPPKARPFLSAAIQDEAKVKSSVGPKVISKAVERGEGRERTSAPFSNPDVSKEALYVAVADFEGDEETNSFREGTLFEVREKNSSGWWFCKVLTGGPCWEGWIPSNYLRKKP", "length": 887, "header": "tr|A0A8V0YMC2-1|A0A8V0YMC2_CHICK Computationally mapped isoform of SH3 and PX domain-containing protein 2B OS=Gallus gallus OX=9031 GN=SH3PXD2B PE=1 SV=1 CANONICAL=A0A8V0YHJ6-1" }, "locus": { "chromosome": "13", "start_pos": 8530662, "end_pos": 8466511, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029650.1", "url": "https://www.ensembl.org/id/ENSGALT00010029650.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017253.1", "url": "https://www.ensembl.org/id/ENSGALP00010017253.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 714, "start_aa": "Thr", "end_pos": 714, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr714", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:427625", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427625", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3Q1LVH9-1", "protein_name": "SH3 and PX domain-containing protein 2B", "gene_name": "SH3PXD2B", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MPPRRSIVEVKVLDVQKRRVPNKHYVYIIRVTWSSGSTEAIYRRYSKFFDLQMQMLDKFPMEGGQKDPKQRIIPFLPGKILFRRSHIRDVAVKRLIPIDEYCKALIQLPPYISQCDEVLQFFETRPEDLNPPKEEHVGKKKSGGDLTSVDPMVLEQYVVVADYQKQESSEISLSVGQVVDIIEKNESGWWFVSTAEEQGWVPATCLEGQDGVQDEFSLQPEEEEKYTVIYPYTARDQDEMNLERGAVVEVIQKNLEGWWKIRYQGKEGWAPASYLRKSSGEPLPPKLAPGSPAHVGVLELDGVSRQQNSVGREKELLNNQRDGRLEGRPVPDGDIRQRSPKMRQRPPPRRDMTIPRGLNLPKPPIPPQVEEEYYTIAEFQTTIPDGISFQAGLKVEVIEKNLSGWWYIQIEDKEGWAPATFIDKYKKTSNASRPNFLAPLPNEVAQLRLGDAAAMENSSGSEASGPSRPLPDAPHSAGDSGTPWAKDWKGGKEVLRKASSDTSSCAGYEEISDPDLEEKPSLPPRKESIIKSEEELQERQRMEQFRGSSPKPPGMILPMIPAKHALPARDGRKAEPKPEKSKLFQLKNETGLECGHRVLAKEVKKPSLRPISKSKAGLPEEKPEAVPQNLFLKSKPQVRPKPAPSPRTEPPQGEDQVDICNLRSKLRPAKSQEKASVDGESSHQAGGGQDGAFSRGFPPGEGPGRAQDRTSKQEGPSPKEAPCRAPPRPAKTTDPVPKATPVPLQEASLQRPVVPPRRPPPPKKTSSSSRPLPEVRGPLPEVRGPLPEVRGPLPEVRGPQRESSEGKAAPAPGRALLVPPKAKPFLSNSSGGQDDMRGKGGLGPRMMGKTGENKEKVAAGPFPSTDGPKDLYVAVANFEGDQDTSSFQEGTVFEVREKNSSGWWFCQVQSGAPSWEGWIPSNYLRKKP", "length": 928 }, "evidence": [ { "id": "A0A8V0YHJ6", "url": "https://omabrowser.org/oma/group/A0A8V0YHJ6/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A1X283-1", "protein_name": "SH3 and PX domain-containing protein 2B", "gene_name": "SH3PXD2B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPPRRSIVEVKVLDVQKRRVPNKHYVYIIRVTWSSGSTEAIYRRYSKFFDLQMQMLDKFPMEGGQKDPKQRIIPFLPGKILFRRSHIRDVAVKRLIPIDEYCKALIQLPPYISQCDEVLQFFETRPEDLNPPKEEHIGKKKSGGDQTSVDPMVLEQYVVVANYQKQESSEISLSVGQVVDIIEKNESGWWFVSTAEEQGWVPATCLEGQDGVQDEFSLQPEEEEKYTVIYPYTARDQDEMNLERGAVVEVIQKNLEGWWKIRYQGKEGWAPASYLKKNSGEPLPPKPGPGSPSHPGALDLDGVSRQQNAVGREKELLSSQRDGRFEGRPVPDGDAKQRSPKMRQRPPPRRDMTIPRGLNLPKPPIPPQVEEEYYTIAEFQTTIPDGISFQAGLKVEVIEKNLSGWWYIQIEDKEGWAPATFIDKYKKTSNASRPNFLAPLPHEVTQLRLGEAAALENNTGSEATGPSRPLPDAPHGVMDSGLPWSKDWKGSKDVLRKASSDMSASAGYEEISDPDMEEKPSLPPRKESIIKSEGELLERERERQRTEQLRGPTPKPPGVILPMMPAKHIPPARDSRRPEPKPDKSRLFQLKNDMGLECGHKVLAKEVKKPNLRPISKSKTDLPEEKPDATPQNPFLKSRPQVRPKPAPSPKTEPPQGEDQVDICNLRSKLRPAKSQDKSLLDGEGPQAVGGQDVAFSRSFLPGEGPGRAQDRTGKQDGLSPKEISCRAPPRPAKTTDPVSKSVPVPLQEAPQQRPVVPPRRPPPPKKTSSSSRPLPEVRGPQCEGHESRAAPTPGRALLVPPKAKPFLSNSLGGQDDTRGKGSLGPWGTGKIGENREKAAAASVPNADGLKDSLYVAVADFEGDKDTSSFQEGTVFEVREKNSSGWWFCQVLSGAPSWEGWIPSNYLRKKP", "length": 911 }, "evidence": [ { "id": "A0A8V0YHJ6", "url": "https://omabrowser.org/oma/group/A0A8V0YHJ6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A2AAY5-1", "protein_name": "SH3 and PX domain-containing protein 2B", "gene_name": "Sh3pxd2b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPPRRSIVEVKVLDVQKRRVPNKHYVYIIRVTWSSGATEAIYRRYSKFFDLQMQMLDKFPMEGGQKDPKQRIIPFLPGKILFRRSHIRDVAVKRLIPIDEYCKALIQLPPYISQCDEVLQFFETRPEDLNPPKEEHIGKKKSGNDPTSVDPMVLEQYVVVADYQKQESSEISLSVGQVVDIIEKNESGWWFVSTAEEQGWVPATCLEGQDGVQDEFSLQPEEEEKYTVIYPYTARDQDEMNLERGAVVEVVQKNLEGWWKIRYQGKEGWAPASYLKKNSGEPLPPKLGPSSPAHSGALDLDGVSRHQNAMGREKELLNNQRDGRFEGRLVPDGDVKQRSPKMRQRPPPRRDMTIPRGLNLPKPPIPPQVEEEYYTIAEFQTTIPDGISFQAGLKVEVIEKSLSGWWYIQMEDKEGWAPATFIDKYKKTSSASRPNFLAPLPHEMTQLRLGDAAATENNTGPEAVGPSRPLPEAPHGAVDSGMLWSKDWKGGKEAPRKASSDLSASTGYEEISDPTQEEKPSLPPRKESIIKSEEELLERERQKMEPLRGSSPKPPGMILPMIPAKHAPLARDSRKPEPKLDKSKFPLRNDMGLECGHKVLAKEVKKPNLRPISRSKAELSEEKVDPTSQNLFMKSRPQVRPKPTPSPKTEPAQSEDHVDIYNLRSKLRPAKSQEKALLDGESHHAAGSHDTALSRSFLPGEGPGHGQDRSGRQDGLSPKETPCRAPPRPAKTTDPGPKNVPVPVQEATLQQRPVVPPRRPPPPKKTSSSPLSCRPLPEVRGAQREESRVAPAAGRALLVPPKAKPFLSNSSVGQDDMRGKGGLGPRVTGKVGETREKAASFLNADGPKDSLYVAVANFEGDEDTSSFQEGTVFEVREKNSSGWWFCQVLSGAPSWEGWIPSNYLRKKP", "length": 908 }, "evidence": [ { "id": "A0A8V0YHJ6", "url": "https://omabrowser.org/oma/group/A0A8V0YHJ6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "M0RCP2-1", "protein_name": "SH3 and PX domain-containing protein 2B", "gene_name": "Sh3pxd2b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPPRRSIVEVKVLDVQKRRVPNKHYVYIIRVTWSSGATEAIYRRYSKFFDLQMQMLDKFPVEGGQKDPKQRIIPFLPGKILFRRSHIRDVAVKRLIPIDEYCKALIQLPPYISQCDEVLQFFETRPEDLNPPKEEHIGKKKSGSDPTSVDPMVLEQYVVVANYQKQESSEISLSVGQVVDIIEKNESGWWFVSTAEEQGWVPATCLEGQDGVQDEFSLQPEEVSWRYCSLPRSVGRRRTLGDLYAISWRQEEKYTVIYPYTARDQDEMNLERGVVVEVIQKNLEGWWKIRFQGKEGWAPASYLKKSSGEPLPPKLGPSSSAHSGALDLDGVSRQQNAVGREKELLNNQRDGRFEGRLAPDGDVKQRSPKMRQRPPPRRDMTIPRGLNLPKPPIPPQVEEEYYTIAEFQTTIPDGISFQAGLKVEVIEKSLSGWWYIQMEDKEGWAPATFIDKYKKTSSASRPNFLAPLPHEMTQLRLGEAAATENNTGPEAVGPSRPLPEAPHGAVDSGMLWSKDWKGGKEAPRKASSDLSASTGYEEISDPTQEEKPSLPPRKESIIKSEEELLERERQKMEPHRGSSPKPPGVILPMIPAKHAPLARDSKKPEPKPDKSKFPLRNDMGLECGHKVLAKEVKKPNLRPISRSKAELPEEKVEPNPQNLFLKSRPQVRPKPTPSPKTEPAQGEDQVDIYNLRSKLRPAKSQEKALLDGESHHAAGGHDTALGRSFLPGEGPGRGQDRSGRQDGLSPKETPCRAPPRPAKTTDPGPKNVPVPVQEATQQRPVVPPRRPPPPKKTSSSPLSCRPLPEVRGSQREESRAIPASGRALLVPPKAKPFLSNSSVGQDDIRGKGGLGPRIAGKVGETREKAASFLNADGPKDSLYVAVANFEGDEDTSSFQEGTVFEVREKNSSGWWFCRVLSGAPSWEGWIPSNYLRKKP", "length": 935 }, "evidence": [ { "id": "A0A8V0YHJ6", "url": "https://omabrowser.org/oma/group/A0A8V0YHJ6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHJ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHJ6" } ], "pmid": "" }, { "name": "podosome", "id": "GO:0002102", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002102", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHJ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHJ6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 7, "go_terms": [ { "name": "heart development", "id": "GO:0007507", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007507", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHJ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHJ6" } ], "pmid": "" }, { "name": "extracellular matrix disassembly", "id": "GO:0022617", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022617", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHJ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHJ6" } ], "pmid": "" }, { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHJ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHJ6" } ], "pmid": "" }, { "name": "bone development", "id": "GO:0060348", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060348", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHJ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHJ6" } ], "pmid": "" }, { "name": "protein localization to membrane", "id": "GO:0072657", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072657", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHJ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHJ6" } ], "pmid": "" }, { "name": "eye development", "id": "GO:0001654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHJ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHJ6" } ], "pmid": "" }, { "name": "superoxide anion generation", "id": "GO:0042554", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042554", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHJ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHJ6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "phosphatidylinositol binding", "id": "GO:0035091", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035091", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHJ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHJ6" } ], "pmid": "" }, { "name": "superoxide-generating NADPH oxidase activator activity", "id": "GO:0016176", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016176", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHJ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHJ6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 196, "end_pos": 198, "annotation": "n_glycosylation_sequon" }, { "start_pos": 34, "end_pos": 36, "annotation": "n_glycosylation_sequon" }, { "start_pos": 433, "end_pos": 435, "annotation": "n_glycosylation_sequon" }, { "start_pos": 462, "end_pos": 464, "annotation": "n_glycosylation_sequon" }, { "start_pos": 875, "end_pos": 877, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YHJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHJ6" }, { "id": "PS50195", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50195" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PX", "eco_id": "ECO_0000259", 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"start_pos": 462, "end_pos": 464 }, { "start_pos": 875, "end_pos": 877 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { 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"phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YHK2-1", "uniprot_ac": "A0A8V0YHK2", "uniprot_id": "A0A8V0YHK2_CHICK", "mass": { "chemical_mass": 32414.0, "monoisotopic_mass": 32414.0 }, "refseq": {}, "gene_names": [ { "name": "RAC2", "type": "recommended", "evidence": [ { "id": "A0A8V0YHK2", "database": "UniProtKB", "url": 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"categories": [ "Protein Classification" ] }, { "id": "A0A8V0YQP4", "url": "https://www.orthodb.org/?gene=A0A8V0YQP4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24072", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24072", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00071", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00071", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-114604", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-114604", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-1222556", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1222556", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-1257604", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1257604", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-5668599", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5668599", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-6811558", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6811558", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9013404", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013404", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "19669", "url": "https://www.rhea-db.org/rhea/19669", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YHK2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHK2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHK2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHK2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQP4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQP4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQP4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQP4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKSLEVGSWPDGVSPFCLVLLPWLISLYPAAACGWGRLRKEEAPATCAETVRAASVSLKERHFAGGLQFLVRVIAQLAVAHRWCKLSRLQAAGKLSSDISSPRHCVAILAMSVAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDSKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASYENVRAKWFPEVRHHCPSTPIILVGTKLDLRDDKDTIEKLKEKKLSPITYPQGLALAKEIDSVKYLECSALTQRGLKTVFDEAIRAVLCPQPTRTKKRACSLL", "length": 293, "header": "tr|A0A8V0YHK2-1|A0A8V0YHK2_CHICK Isoform 1 of small monomeric GTPase OS=Gallus gallus OX=9031 GN=RAC2 PE=1 SV=1 CANONICAL=A0A8V0YHK2-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YHK2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHK2/entry#A0A8V0YHK2-1", "sequence": { "sequence": "MKSLEVGSWPDGVSPFCLVLLPWLISLYPAAACGWGRLRKEEAPATCAETVRAASVSLKERHFAGGLQFLVRVIAQLAVAHRWCKLSRLQAAGKLSSDISSPRHCVAILAMSVAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDSKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASYENVRAKWFPEVRHHCPSTPIILVGTKLDLRDDKDTIEKLKEKKLSPITYPQGLALAKEIDSVKYLECSALTQRGLKTVFDEAIRAVLCPQPTRTKKRACSLL", "length": 293, "header": "tr|A0A8V0YHK2-1|A0A8V0YHK2_CHICK Isoform 1 of small monomeric GTPase OS=Gallus gallus OX=9031 GN=RAC2 PE=1 SV=1 CANONICAL=A0A8V0YHK2-1" }, "locus": { "chromosome": "1", "start_pos": 51462226, "end_pos": 51456227, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034679.1", "url": "https://www.ensembl.org/id/ENSGALT00010034679.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020350.1", "url": "https://www.ensembl.org/id/ENSGALP00010020350.1" } ] } }, { "isoform_ac": "A0A8V0YQP4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHK2/entry#A0A8V0YQP4-1", "sequence": { "sequence": "MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDSKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASYENVRAKWFPEVRHHCPSTPIILVGTKLDLRDDKDTIEKLKEKKLSPITYPQGLALAKEIGRCLQATLKKERQKIRASSQLYEASLEVYLKNKGHGTKRTSGDSGRRSAP", "length": 199, "header": "tr|A0A8V0YQP4-1|A0A8V0YQP4_CHICK Computationally mapped isoform of small monomeric GTPase OS=Gallus gallus OX=9031 GN=RAC2 PE=1 SV=1 CANONICAL=A0A8V0YHK2-1" }, "locus": { "chromosome": "1", "start_pos": 51461071, "end_pos": 51454341, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034686.1", "url": "https://www.ensembl.org/id/ENSGALT00010034686.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020353.1", "url": "https://www.ensembl.org/id/ENSGALP00010020353.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "R-GGA-114604", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-114604", "resource": "Reactome", "description": "GPVI-mediated activation cascade" }, { "id": "R-GGA-1222556", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1222556", "resource": "Reactome", "description": "ROS and RNS production in phagocytes" }, { "id": "R-GGA-1257604", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1257604", "resource": "Reactome", "description": "PIP3 activates AKT signaling" }, { "id": "R-GGA-5668599", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5668599", "resource": "Reactome", "description": "RHO GTPases Activate NADPH Oxidases" }, { "id": "R-GGA-6811558", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6811558", "resource": "Reactome", "description": "PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling" }, { "id": "R-GGA-9013404", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013404", "resource": "Reactome", "description": "RAC2 GTPase cycle" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "GTPase activity", "id": "GO:0003924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003924", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHK2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHK2" } ], "pmid": "" }, { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHK2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHK2" } ], "pmid": "" }, { "name": "protein kinase binding", "id": "GO:0019901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019901", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHK2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHK2" } ], "pmid": "" }, { "name": "G protein activity", "id": "GO:0003925", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003925", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHK2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHK2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHK2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHK2" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHK2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHK2" } ], "pmid": "" }, { "name": "cytoplasmic vesicle", "id": "GO:0031410", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031410", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHK2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHK2" } ], "pmid": "" }, { "name": "cell projection", "id": "GO:0042995", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042995", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHK2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHK2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 10, "go_terms": [ { "name": "chemotaxis", "id": "GO:0006935", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006935", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHK2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHK2" } ], "pmid": "" }, { "name": "actin filament organization", "id": "GO:0007015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007015", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHK2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHK2" } ], "pmid": "" }, { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHK2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHK2" } ], "pmid": "" }, { "name": "regulation of actin cytoskeleton organization", "id": "GO:0032956", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032956", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHK2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHK2" } ], "pmid": "" }, { "name": "small GTPase-mediated signal transduction", "id": "GO:0007264", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007264", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHK2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHK2" } ], "pmid": "" }, { "name": "regulation of cell shape", "id": "GO:0008360", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008360", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHK2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHK2" } ], "pmid": "" }, { "name": "positive regulation of lamellipodium assembly", "id": "GO:0010592", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010592", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHK2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHK2" } ], "pmid": "" }, { "name": "establishment or maintenance of cell polarity", "id": "GO:0007163", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007163", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHK2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHK2" } ], "pmid": "" }, { "name": "cortical cytoskeleton organization", "id": "GO:0030865", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030865", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHK2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHK2" } ], "pmid": "" }, { "name": "regulation of neutrophil migration", "id": "GO:1902622", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902622", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHK2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHK2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 140, "end_pos": 142, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "19669", "name": "", "equation": "GTP + H2O = GDP + phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YVX9-1", "F1NSA8-1", "R4GJA4-1", "A0A1L1RKZ0-1", "E1BUS1-1", "Q5ZHW4-1", "Q90694-1", "P08070-1", "P09642-1", "P09643-1", "P09644-1", "P09645-1", "Q5F352-1", "Q5ZMS3-1", "Q90705-1", "Q90835-1", "Q90965-1", "Q98932-1", "A0A3Q2UHM4-1", "Q5ZHX1-1", "A0A1D5PT95-1", "E1BQI2-1", "F1NPF0-1", "A0A8V0XVU5-1", "A0A8V0XBX5-1", "A0A8V0Z564-1", "A0A8V0Y9R6-1", "A0A1D5PM27-1", "A0A8V0Z8U4-1", "A0A8V0ZJW2-1", "A0A8V1ABB1-1", "A0A8V0YDX6-1", "E1BWN3-1", "Q5F499-1", "Q5ZKU5-1", "P02552-1", "P08642-1", "P26990-1", "P42558-1", "Q5F470-1", "Q5ZIT5-1", "Q5ZJN2-1", "P50146-1", "A0A8V0ZNW3-1", "A0A8V0YIM0-1", "A0A8V0ZRZ2-1", "A0A8V1A9Z8-1", "Q1KME6-1", "Q5ZLG1-1", "P84172-1", "A0A8V1ACG4-1", "A0A8V0YTL7-1", "A0A3Q2UG55-1", "A0A8V1AIF5-1", "Q5ZHV1-1", "A0A8V0Z5P2-1", "A0A8V0Y4A4-1", "A0A8V0YA62-1", "A0A8V0YVM3-1", "A0A1D5P1F5-1", "A0A8V1ADZ7-1", "F1NWF1-1", "A0A8V1AP30-1", "A0A8V0XDD5-1", "A0A8V0XMC5-1", "A0A8V0YWW1-1", "A0A8V0ZR14-1", "A0A8V0Y2H3-1", "Q5ZJD3-1", "Q5ZM73-1", "Q5ZM83-1", "A0A8V0YTY9-1", "A0A8V0ZXW3-1", "A0A8V1AHB3-1", "A0A8V0YDI7-1", "A0A1D5NV13-1", "A0A8V0XGK7-1", "A0A8V0YHK2-1", "A0A8V0XC33-1", "A0A8V0XKC3-1", "F1P278-1", "A0A8V0ZG00-1", "A0A8V1AGP3-1", "A0A8V1AN75-1", "A0A8V0Z416-1", "A0A8V1A0V4-1", "A0A8V1A8Q7-1", "A0A8V1ABD3-1", "A0A8V1API8-1", "A0A8V0YIU8-1", "A0A8V0X962-1", "A0A8V1AKH3-1", "P79784-1", "A0A1D5P533-1", "A0A8V1A8I5-1", "A0A8V1AE09-1", "Q9PSX7-1", "Q5ZKR4-1", "A0A8V0YGN8-1", "A0A8V0XNL0-1", "A0A8V0Y3H2-1" ], "evidence": [ { "id": "19669", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/19669" } ] }, { "id": "R-GGA-114542", "name": "RAC1,RAC2,RHOG activate PI3K", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YHK2-1", "A0A8V0Z8U4-1" ], "evidence": [ { "id": "R-GGA-114542", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-114542" } ] }, { "id": "R-GGA-2316434", "name": "PI3K phosphorylates PIP2 to PIP3", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q91044-1", "E1C093-1", "A0A8V0YHK2-1", "A0M8T9-1", "A0A8V0XB17-1", "A0A8V0YLC3-1", "A0A8V0Z7L6-1", "F1NCL8-1", "Q90687-1", "A0A8V0XNF4-1", "A0A8V0XQ80-1", "A0A8V0YCV8-1", "A0A8V0YYZ7-1", "A0A8V0ZE65-1", "A0A8V0ZXS7-1", "A0A8V1A7N1-1", "F1NHX1-1", "A0A8V0YZE5-1", "A0A8V0Z0R8-1", "A0A8V0Z8U4-1", "A0A8V0ZDU6-1", "A0A3Q2U639-1", "Q08156-1", "A0A8V0YIT6-1" ], "evidence": [ { "id": "R-GGA-2316434", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2316434" } ] }, { "id": "R-GGA-442273", "name": "VAV1 is a GEF for Rho/Rac family GTPases", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YHK2-1", "A0A8V0Z8U4-1", "Q90694-1" ], "evidence": [ { "id": "R-GGA-442273", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-442273" } ] }, { "id": "R-GGA-5668605", "name": "RAC2:GTP binds NOX2 complex", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "phagocytic vesicle membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YHK2-1" ], "evidence": [ { "id": "R-GGA-5668605", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5668605" } ] }, { "id": "R-GGA-5668629", "name": "Production of phagocyte oxygen radicals by NOX2 complex bound to RAC2:GTP", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, phagocytic vesicle, phagocytic vesicle membrane, phagolysosome", "input_participant_list": [ "R-ALL-1236709" ], "output_participant_list": [ "R-ALL-2000345" ], "enzyme_list": [ "A0A8V0YHK2-1" ], "evidence": [ { "id": "R-GGA-5668629", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5668629" } ] }, { "id": "R-GGA-6789092", "name": "NOX2 generates superoxide anion from oxygen", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, phagocytic vesicle membrane, phagocytic vesicle lumen", "input_participant_list": [ "R-ALL-1222561" ], "output_participant_list": [ "R-ALL-1222461" ], "enzyme_list": [ "A0A8V0YHK2-1" ], "evidence": [ { "id": "R-GGA-6789092", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6789092" } ] }, { "id": "R-GGA-9014293", "name": "RAC2 GDIs block activation of RAC2", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YHK2-1" ], "evidence": [ { "id": "R-GGA-9014293", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9014293" } ] }, { "id": "R-GGA-9014294", "name": "RAC2 binds effectors at the plasma membrane", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YHK2-1", "E1BS97-1", "E1C3P6-1", "A0A3Q2TRY2-1", "Q90694-1", "A0A8V0Y955-1" ], "evidence": [ { "id": "R-GGA-9014294", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9014294" } ] }, { "id": "R-GGA-9014295", "name": "RAC2 GAPs stimulate RAC2 GTPase activity", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YHK2-1" ], "evidence": [ { "id": "R-GGA-9014295", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9014295" } ] }, { "id": "R-GGA-9014296", "name": "RAC2 GEFs activate RAC2", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0X8M1-1", "A0A8V0YHK2-1" ], "evidence": [ { "id": "R-GGA-9014296", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9014296" } ] }, { "id": "R-GGA-9014420", "name": "RAC2 translocates to the phagocytic vesicle membrane", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "phagocytic vesicle membrane, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YHK2-1" ], "evidence": [ { "id": "R-GGA-9014420", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9014420" } ] }, { "id": "R-GGA-9014424", "name": "RAC2 binds effectors at the phagocytic vesicle membrane", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "phagocytic vesicle membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YHK2-1" ], "evidence": [ { "id": "R-GGA-9014424", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9014424" } ] }, { "id": "R-GGA-9714477", "name": "RAC2 binds effectors at the mitochondrial outer membrane", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "mitochondrial outer membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YHK2-1" ], "evidence": [ { "id": "R-GGA-9714477", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9714477" } ] }, { "id": "R-GGA-9714480", "name": "RAC2 translocates to the mitochondrial membrane", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "mitochondrial outer membrane, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YHK2-1" ], "evidence": [ { "id": "R-GGA-9714480", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9714480" } ] }, { "id": "R-GGA-9714483", "name": "RAC2 translocates to the ER membrane", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "endoplasmic reticulum membrane, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YHK2-1" ], "evidence": [ { "id": "R-GGA-9714483", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9714483" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-1222461", "participant_name": "O2.- [phagocytic vesicle lumen]", "crossref": [ { "id": "C00704", "database": "COMPOUND", "url": "" }, { "id": "18421", "database": "ChEBI", "url": "" }, { "id": "HMDB0002168", "database": "HMDB Metabolite", "url": "" } ] }, { "participant_id": "R-ALL-1222561", "participant_name": "O2 [phagocytic vesicle lumen]", "crossref": [ { "id": "15379", "database": "ChEBI", "url": "" }, { "id": "8145133", "database": "PubChem Substance", "url": "" }, { "id": "C00007", "database": "COMPOUND", "url": "" }, { "id": "HMDB0001377", "database": "HMDB Metabolite", "url": "" } ] }, { "participant_id": "R-ALL-1236709", "participant_name": "O2 [phagolysosome]", "crossref": [ { "id": "15379", "database": "ChEBI", "url": "" }, { "id": "8145133", "database": "PubChem Substance", "url": "" }, { "id": "C00007", "database": "COMPOUND", "url": "" }, { "id": "HMDB0001377", "database": "HMDB Metabolite", "url": "" } ] }, { "participant_id": "R-ALL-2000345", "participant_name": "O2.- [phagolysosome]", "crossref": [ { "id": "C00704", "database": "COMPOUND", "url": "" }, { "id": "18421", "database": "ChEBI", "url": "" }, { "id": "HMDB0002168", "database": "HMDB Metabolite", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A0A1D5NV13", "gene_name": "RIT2", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5NV13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NV13" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A1D5NV13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NV13" } ] } ] }, { "uniprot_ac": "A0A1D5P1F5", "gene_name": "RAB40C", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5P1F5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P1F5" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A1D5P1F5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P1F5" } ] } ] }, { "uniprot_ac": "A0A1D5P533", "gene_name": "RASEF", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5P533", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P533" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A1D5P533", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P533" } ] } ] }, { "uniprot_ac": "A0A1D5PM27", "gene_name": "OPA1", "activity": [ { "ec_number": "3.6.5.5", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5PM27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PM27" } ] }, { "ec_number": "3.6.5.5", "activity": "", "evidence": [ { "id": "A0A1D5PM27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PM27" } ] } ] }, { "uniprot_ac": "A0A1D5PT95", "gene_name": "KRAS", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5PT95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PT95" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A1D5PT95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PT95" } ] } ] }, { "uniprot_ac": "A0A1L1RKZ0", "gene_name": "RASL11AL", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A1L1RKZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RKZ0" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A1L1RKZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RKZ0" } ] } ] }, { "uniprot_ac": "A0A3Q2TRY2", "gene_name": "TAOK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q2TRY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TRY2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q2TRY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TRY2" } ] } ] }, { "uniprot_ac": "A0A3Q2U639", "gene_name": "FYN", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q2U639", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U639" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A3Q2U639", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U639" } ] } ] }, { "uniprot_ac": "A0A3Q2UG55", "gene_name": "RAB9B", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q2UG55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UG55" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A3Q2UG55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UG55" } ] } ] }, { "uniprot_ac": "A0A3Q2UHM4", "gene_name": "DNM1L", "activity": [ { "ec_number": "3.6.5.5", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q2UHM4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UHM4" } ] }, { "ec_number": "3.6.5.5", "activity": "", "evidence": [ { "id": "A0A3Q2UHM4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UHM4" } ] } ] }, { "uniprot_ac": "A0A8V0X8M1", "gene_name": "TRIO", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X8M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X8M1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0X8M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X8M1" } ] } ] }, { "uniprot_ac": "A0A8V0X962", "gene_name": "RAB31", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0X962", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X962" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V0X962", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X962" } ] } ] }, { "uniprot_ac": "A0A8V0XB17", "gene_name": "FGFR2", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XB17", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XB17" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0XB17", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XB17" } ] } ] }, { "uniprot_ac": "A0A8V0XBX5", "gene_name": "RAP2B", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XBX5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XBX5" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V0XBX5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XBX5" } ] } ] }, { "uniprot_ac": "A0A8V0XC33", "gene_name": "RAB23", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XC33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XC33" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V0XC33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XC33" } ] } ] }, { "uniprot_ac": "A0A8V0XDD5", "gene_name": "RAB12", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XDD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XDD5" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V0XDD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XDD5" } ] } ] }, { "uniprot_ac": "A0A8V0XGK7", "gene_name": "RAB6A", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XGK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XGK7" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V0XGK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XGK7" } ] } ] }, { "uniprot_ac": "A0A8V0XKC3", "gene_name": "RAB18", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XKC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XKC3" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V0XKC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XKC3" } ] } ] }, { "uniprot_ac": "A0A8V0XMC5", "gene_name": "RAB10L", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XMC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMC5" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V0XMC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMC5" } ] } ] }, { "uniprot_ac": "A0A8V0XNF4", "gene_name": "EGFR", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XNF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNF4" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0XNF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNF4" } ] } ] }, { "uniprot_ac": "A0A8V0XNL0", "gene_name": "RABL2A", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XNL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNL0" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V0XNL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNL0" } ] } ] }, { "uniprot_ac": "A0A8V0XQ80", "gene_name": "FLT3", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XQ80", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ80" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0XQ80", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ80" } ] } ] }, { "uniprot_ac": "A0A8V0XVU5", "gene_name": "RASL11A", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XVU5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XVU5" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V0XVU5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XVU5" } ] } ] }, { "uniprot_ac": "A0A8V0Y2H3", "gene_name": "RAB10", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0Y2H3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2H3" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V0Y2H3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2H3" } ] } ] }, { "uniprot_ac": "A0A8V0Y3H2", "gene_name": "GPN1", "activity": [ { "ec_number": "3.6.5.-", "activity": "", "evidence": [ { "id": "A0A8V0Y3H2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y3H2" } ] } ] }, { "uniprot_ac": "A0A8V0Y4A4", "gene_name": "RAB24", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0Y4A4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y4A4" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V0Y4A4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y4A4" } ] } ] }, { "uniprot_ac": "A0A8V0Y955", "gene_name": "PAK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y955", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y955" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y955", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y955" } ] } ] }, { "uniprot_ac": "A0A8V0Y9R6", "gene_name": "RAP1B", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0Y9R6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9R6" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V0Y9R6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9R6" } ] } ] }, { "uniprot_ac": "A0A8V0YA62", "gene_name": "RAB28", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YA62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YA62" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V0YA62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YA62" } ] } ] }, { "uniprot_ac": "A0A8V0YCV8", "gene_name": "NTRK2", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YCV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCV8" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0YCV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCV8" } ] } ] }, { "uniprot_ac": "A0A8V0YDI7", "gene_name": "RAB17", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YDI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDI7" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V0YDI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDI7" } ] } ] }, { "uniprot_ac": "A0A8V0YDX6", "gene_name": "", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YDX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDX6" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V0YDX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDX6" } ] } ] }, { "uniprot_ac": "A0A8V0YGN8", "gene_name": "RAB21", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YGN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGN8" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V0YGN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGN8" } ] } ] }, { "uniprot_ac": "A0A8V0YHK2", "gene_name": "RAC2", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YHK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHK2" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V0YHK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHK2" } ] } ] }, { "uniprot_ac": "A0A8V0YIM0", "gene_name": "SAR1B", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YIM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIM0" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V0YIM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIM0" } ] } ] }, { "uniprot_ac": "A0A8V0YIT6", "gene_name": "ERBB4", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YIT6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIT6" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0YIT6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIT6" } ] } ] }, { "uniprot_ac": "A0A8V0YIU8", "gene_name": "GTPBP1", "activity": [ { "ec_number": "3.6.5.3", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YIU8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIU8" } ] }, { "ec_number": "3.6.5.3", "activity": "", "evidence": [ { "id": "A0A8V0YIU8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIU8" } ] } ] }, { "uniprot_ac": "A0A8V0YLC3", "gene_name": "PDGFRA", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YLC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLC3" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0YLC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLC3" } ] } ] }, { "uniprot_ac": "A0A8V0YTL7", "gene_name": "DNM3", "activity": [ { "ec_number": "3.6.5.5", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YTL7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTL7" } ] }, { "ec_number": "3.6.5.5", "activity": "", "evidence": [ { "id": "A0A8V0YTL7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTL7" } ] } ] }, { "uniprot_ac": "A0A8V0YTY9", "gene_name": "EIF5B", "activity": [ { "ec_number": "3.6.5.3", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YTY9", "database": 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"id": "A0A8V0YVX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YVX9" } ] } ] }, { "uniprot_ac": "A0A8V0YWW1", "gene_name": "RAB33A", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YWW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YWW1" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V0YWW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YWW1" } ] } ] }, { "uniprot_ac": "A0A8V0YYZ7", "gene_name": "FGFR3", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YYZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYZ7" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0YYZ7", "database": "UniProtKB", "url": 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} ] }, { "uniprot_ac": "A0A8V0ZDU6", "gene_name": "SRC", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZDU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDU6" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0ZDU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDU6" } ] } ] }, { "uniprot_ac": "A0A8V0ZE65", "gene_name": "NTRK3", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZE65", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE65" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0ZE65", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE65" } ] } ] }, { "uniprot_ac": "A0A8V0ZG00", "gene_name": "RAB35", 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"evidence": [ { "id": "A0A8V0ZXW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXW3" } ] } ] }, { "uniprot_ac": "A0A8V1A0V4", "gene_name": "RAB18L", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V1A0V4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0V4" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V1A0V4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0V4" } ] } ] }, { "uniprot_ac": "A0A8V1A7N1", "gene_name": "ERBB3", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7N1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7N1" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V1A7N1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7N1" } ] } ] }, { "uniprot_ac": "A0A8V1A8I5", "gene_name": "RABL3", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V1A8I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8I5" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V1A8I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8I5" } ] } ] }, { "uniprot_ac": "A0A8V1A8Q7", "gene_name": "RIT1", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V1A8Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8Q7" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V1A8Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8Q7" } ] } ] }, { "uniprot_ac": "A0A8V1A9Z8", "gene_name": "RAB14", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V1A9Z8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9Z8" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V1A9Z8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9Z8" } ] } ] }, { "uniprot_ac": "A0A8V1ABB1", "gene_name": "", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V1ABB1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABB1" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V1ABB1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABB1" } ] } ] }, { "uniprot_ac": "A0A8V1ABD3", "gene_name": "RAB36", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V1ABD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABD3" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V1ABD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABD3" } ] } ] }, { "uniprot_ac": "A0A8V1ACG4", "gene_name": "DNM1", "activity": [ { "ec_number": "3.6.5.5", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V1ACG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACG4" } ] }, { "ec_number": "3.6.5.5", "activity": "", "evidence": [ { "id": "A0A8V1ACG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACG4" } ] } ] }, { "uniprot_ac": "A0A8V1ADZ7", "gene_name": "RHOT1", "activity": [ { "ec_number": "3.6.5.-", "activity": "", "evidence": [ { "id": "A0A8V1ADZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADZ7" } ] } ] }, { "uniprot_ac": "A0A8V1AE09", "gene_name": "RAB43", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V1AE09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE09" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V1AE09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE09" } ] } ] }, { "uniprot_ac": "A0A8V1AGP3", "gene_name": "RAB34", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V1AGP3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGP3" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V1AGP3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGP3" } ] } ] }, { "uniprot_ac": "A0A8V1AHB3", "gene_name": "RAB2B", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V1AHB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHB3" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V1AHB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHB3" } ] } ] }, { "uniprot_ac": "A0A8V1AIF5", "gene_name": "RAC3", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V1AIF5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIF5" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V1AIF5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIF5" } ] } ] }, { "uniprot_ac": "A0A8V1AKH3", "gene_name": "RABL6", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V1AKH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKH3" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V1AKH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKH3" } ] } ] }, { "uniprot_ac": "A0A8V1AN75", "gene_name": "RAB37", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V1AN75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AN75" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V1AN75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AN75" } ] } ] }, { "uniprot_ac": "A0A8V1AP30", "gene_name": "RAB40B", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V1AP30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP30" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V1AP30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP30" } ] } ] }, { "uniprot_ac": "A0A8V1API8", "gene_name": "RASL10B", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V1API8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1API8" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V1API8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1API8" } ] } ] }, { "uniprot_ac": "A0M8T9", "gene_name": "MET", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0M8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0M8T9" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0M8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0M8T9" } ] } ] }, { "uniprot_ac": "E1BQI2", "gene_name": "RAP2A", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "E1BQI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQI2" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "E1BQI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQI2" } ] } ] }, { "uniprot_ac": "E1BS97", "gene_name": "PAK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BS97", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BS97" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BS97", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BS97" } ] } ] }, { "uniprot_ac": "E1BUS1", "gene_name": "RERGL", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "E1BUS1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUS1" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "E1BUS1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUS1" } ] } ] }, { "uniprot_ac": "E1BWN3", "gene_name": "RASL11B", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "E1BWN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWN3" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "E1BWN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWN3" } ] } ] }, { "uniprot_ac": "E1C093", "gene_name": "PIK3CG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.154", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.154", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] } ] }, { "uniprot_ac": "E1C3P6", "gene_name": "PAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C3P6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C3P6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C3P6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C3P6" } ] } ] }, { "uniprot_ac": "F1NCL8", "gene_name": "FGFR4", "activity": [ { "ec_number": "2.7.10.1", "activity": 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"field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YHL9-1", "uniprot_ac": "A0A8V0YHL9", "uniprot_id": "A0A8V0YHL9_CHICK", "mass": { "chemical_mass": 64478.0, "monoisotopic_mass": 64478.0 }, "refseq": { "ac": "NP_001384585", "name": "transcription factor COE1 isoform 2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384585" }, "gene_names": [ { "name": "EBF1", "type": "recommended", "evidence": [ { "id": "A0A8V0YHL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHL9" } ] }, { "name": "EBF1", "type": "synonym", "evidence": [ { "id": "NP_001384585", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384585" } ] }, { "name": "EBF", "type": "synonym", "evidence": [ { "id": "NP_001384585", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384585" } ] }, { "name": "cEBF1", "type": "synonym", "evidence": [ { "id": "NP_001384585", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384585" } ] } ], "protein_names": [ { "name": "Transcription factor COE1", "type": "recommended", "evidence": [ { "id": "A0A8V0YHL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHL9/entry#names_and_taxonomy" } ] }, { "name": "Early B-cell factor", "type": "synonym", "evidence": [ { "id": "A0A8V0YHL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHL9/entry#names_and_taxonomy" } ] }, { "name": "early B-cell factor 1 protein", "type": "synonym", "evidence": [ { "id": "NP_001384585", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384585" } ] }, { "name": "transcription factor COE1 isoform 2", "type": "synonym", "evidence": [ { "id": "NP_001384585", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384585" } ] }, { "name": "transcription factor COE1", "type": "synonym", "evidence": [ { "id": "NP_001384585", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384585" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: SRR13267658.14816.1, SRR13267659.71043.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992393 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000256.1. On Nov 24, 2021 this sequence version replaced XP_015149224.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001384585", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384585" } ] }, { "annotation": "CEbf1 gene is considered as a medial sclerotome marker, downstream to and regulated by the notochord derived Shh, which may be functionally involved in somitogenesis", "evidence": [ { "database": "RefSeq", "id": "NP_001384585", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384585" }, { "database": "PubMed", "id": "25455103", "url": "https://glygen.org/publication/PubMed/25455103" } ] }, { "annotation": "Early B-cell factor-1 expression in the feather bud is under the control of Sonic Hedgehog and Bmp4 signals and that expression may play a role in the normal development of feathers", "evidence": [ { "database": "RefSeq", "id": "NP_001384585", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384585" }, { "database": "PubMed", "id": "24365066", "url": "https://glygen.org/publication/PubMed/24365066" } ] }, { "annotation": "Ectopic expression of retinoic acid (RA) led to up-regulation of cEbf2, 3 but did not change cEbf1 expression in somites. Expectedly, inhibition of RA by disulfiram resulted in downregulation of cEbf2, 3, but did not change cEbf1 expression in somites. The same RA gain and loss of function experiments did not change cEbf1-3 expression in pharyngeal arches.", "evidence": [ { "database": "RefSeq", "id": "NP_001384585", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384585" }, { "database": "PubMed", "id": "25331756", "url": "https://glygen.org/publication/PubMed/25331756" } ] }, { "annotation": "Expression and function of Ebf1 gene during chondrogenesis in chick embryo limb buds.", "evidence": [ { "database": "RefSeq", "id": "NP_001384585", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384585" }, { "database": "PubMed", "id": "34384862", "url": "https://glygen.org/publication/PubMed/34384862" } ] }, { "annotation": "GCN5 binds to the 5'-flanking region of the chicken PRKCQ gene and acetylates histone H3, and EBF1 binds to the 5'-flanking region of the gene surrounding putative EBF1 binding motifs.", "evidence": [ { "database": "RefSeq", "id": "NP_001384585", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384585" }, { "database": "PubMed", "id": "24657615", "url": "https://glygen.org/publication/PubMed/24657615" } ] }, { "annotation": "Key pioneer transcription factor of B-cell specification and commitment. Recognizes variations of the palindromic sequence 5'-ATTCCCNNGGGAATT-3'. Operates in a transcription factor network to activate B-cell-specific genes and repress genes associated with alternative cell fates. For instance, positively regulates many B-cell specific genes including BCR or CD40 while repressing genes that direct cells into alternative lineages, including GATA3 and TCF7 for the T-cell lineage. In addition to its role during lymphopoiesis, controls the thermogenic gene program in adipocytes during development and in response to environmental cold.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHL3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHL3#function" }, { "database": "UniProtKB", "id": "ARBA00054317", "url": "https://www.uniprot.org/uniprotkb/ARBA00054317#function" }, { "database": "UniProtKB", "id": "A0A8V0YHL9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHL9#function" }, { "database": "UniProtKB", "id": "F1N9Q3", "url": "https://www.uniprot.org/uniprotkb/F1N9Q3#function" } ] }, { "annotation": "This is the first report on a novel EBF1 function in immature B cells as a powerful repressor of Blimp-1 gene expression.", "evidence": [ { "database": "RefSeq", "id": "NP_001384585", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384585" }, { "database": "PubMed", "id": "22634309", "url": "https://glygen.org/publication/PubMed/22634309" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHL9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHL9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "EBF1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHL9", "locus": { "chromosome": "13", "start_pos": 10550316, "end_pos": 10287792, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012921", "url": "https://www.ensembl.org/id/ENSGALG00010012921" } ] } } ], "crossref": [ { "id": "A0A8V0YHL9", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YHL9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000003699", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000003699", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd01175", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01175", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd11606", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11606", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "395512", "url": "https://www.ncbi.nlm.nih.gov/gene/395512", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002909", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002909", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003523", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003523", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014756", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014756", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018350", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018350", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032200", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032200", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032201", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032201", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038006", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038006", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038173", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038173", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "FGSTTVW", "url": "https://omabrowser.org/oma/group/FGSTTVW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YHL3", "url": "https://www.orthodb.org/?gene=A0A8V0YHL3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YHL9", "url": "https://www.orthodb.org/?gene=A0A8V0YHL9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1N9Q3", "url": "https://www.orthodb.org/?gene=F1N9Q3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10747", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10747", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01833", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01833", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16422", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16422", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16423", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16423", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001384585", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384585", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YHL3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHL3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHL3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHL3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHL9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHL9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHL9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHL9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N9Q3", "url": "https://www.uniprot.org/uniprotkb/F1N9Q3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N9Q3-1", "url": "https://www.uniprot.org/uniprotkb/F1N9Q3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MFGIQESIQRSGSSMKEEPLGAGMNAVRTWMQGAGVLDASTAAQSGVGLARAHFEKQPPSNLRKSNFFHFVLALYDRQGQPVEIERTAFVGFVEKEKEANSEKTNNGIHYRLQLLYSNGIRTEQDFYVRLIDSMTKQAIVYEGQDKNPEMCRVLLTHEIMCSRCCDKKSCGNRNETPSDPVIIDRFFLKFFLKCNQNCLKNAGNPRDMRRFQVVVSTTVNVDGHVLAVSDNMFVHNNSKHGRRARRLDPSEGTPSYLEHAATPCIKAISPSEGWTTGGATVIIIGDNFFDGLQVIFGTMLVWSELITPHAIRVQTPPRHIPGVVEVTLSYKSKQFCKGTPGRFIYTALNEPTIDYGFQRLQKVIPRHPGDPERLPKEVILKRAADLVEALYGMPHNNQEIILKRAADIAEALYSVPRNHNQLPALANTSVHAGMMGVNSFSGQLAVNVSEASQATSQGFTRNSSSVSPHGYVPSTTPQQTNYNSVTTSMNGYGNAGMSNLGGSPTFLNGSAANSPYAIVPSSPTMASSTSLPSNCSSSSGIFSFSPANMVSAVKQKSAFAPVVRPQTSPPPTCTSTNGNSLQAISGMIVPPM", "length": 592, "header": "tr|A0A8V0YHL9-1|A0A8V0YHL9_CHICK Isoform 1 of Transcription factor COE1 OS=Gallus gallus OX=9031 GN=EBF1 PE=3 SV=1 CANONICAL=A0A8V0YHL9-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YHL3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHL9/entry#A0A8V0YHL3-1", "sequence": { "sequence": "MFGIQESIQRSGSSMKEEPLGAGMNAVRTWMQGAGVLDASTAAQSGVGLARAHFEKQPPSNLRKSNFFHFVLALYDRQGQPVEIERTAFVGFVEKEKEANSEKTNNGIHYRLQLLYSNGIRTEQDFYVRLIDSMTKQAIVYEGQDKNPEMCRVLLTHEIMCSRCCDKKSCGNRNETPSDPVIIDRFFLKFFLKCNQNCLKNAGNPRDMRRFQVVVSTTVNVDGHVLAVSDNMFVHNNSKHGRRARRLDPSEGTPSYLEHATPCIKAISPSEGWTTGGATVIIIGDNFFDGLQVIFGTMLVWSELITPHAIRVQTPPRHIPGVVEVTLSYKSKQFCKGTPGRFIYTALNEPTIDYGFQRLQKVIPRHPGDPERLPKEVILKRAADLVEALYGMPHNNQEIILKRAADIAEALYSVPRNHNQLPALANTSVHAGMMGVNSFSGQLAVNVSEASQATSQGFTRNSSSVSPHGYVPSTTPQQTNYNSVTTSMNGYGNAGMSNLGGSPTFLNGSAANSPYAIVPSSPTMASSTSLPSNCSSSSGIFSFSPANMVSAVKQKSAFAPVVRPQTSPPPTCTSTNGNSLQGVWQPPYL", "length": 589, "header": "tr|A0A8V0YHL3-1|A0A8V0YHL9_CHICK Computationally mapped isoform of Transcription factor COE1 OS=Gallus gallus OX=9031 GN=EBF1 PE=3 SV=1 CANONICAL=A0A8V0YHL9-1" }, "locus": { "chromosome": "13", "start_pos": 10542929, "end_pos": 10288581, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031018.1", "url": "https://www.ensembl.org/id/ENSGALT00010031018.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018029.1", "url": "https://www.ensembl.org/id/ENSGALP00010018029.1" } ] } }, { "isoform_ac": "A0A8V0YHL9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHL9/entry#A0A8V0YHL9-1", "sequence": { "sequence": "MFGIQESIQRSGSSMKEEPLGAGMNAVRTWMQGAGVLDASTAAQSGVGLARAHFEKQPPSNLRKSNFFHFVLALYDRQGQPVEIERTAFVGFVEKEKEANSEKTNNGIHYRLQLLYSNGIRTEQDFYVRLIDSMTKQAIVYEGQDKNPEMCRVLLTHEIMCSRCCDKKSCGNRNETPSDPVIIDRFFLKFFLKCNQNCLKNAGNPRDMRRFQVVVSTTVNVDGHVLAVSDNMFVHNNSKHGRRARRLDPSEGTPSYLEHAATPCIKAISPSEGWTTGGATVIIIGDNFFDGLQVIFGTMLVWSELITPHAIRVQTPPRHIPGVVEVTLSYKSKQFCKGTPGRFIYTALNEPTIDYGFQRLQKVIPRHPGDPERLPKEVILKRAADLVEALYGMPHNNQEIILKRAADIAEALYSVPRNHNQLPALANTSVHAGMMGVNSFSGQLAVNVSEASQATSQGFTRNSSSVSPHGYVPSTTPQQTNYNSVTTSMNGYGNAGMSNLGGSPTFLNGSAANSPYAIVPSSPTMASSTSLPSNCSSSSGIFSFSPANMVSAVKQKSAFAPVVRPQTSPPPTCTSTNGNSLQAISGMIVPPM", "length": 592, "header": "tr|A0A8V0YHL9-1|A0A8V0YHL9_CHICK Isoform 1 of Transcription factor COE1 OS=Gallus gallus OX=9031 GN=EBF1 PE=3 SV=1 CANONICAL=A0A8V0YHL9-1" }, "locus": { "chromosome": "13", "start_pos": 10547962, "end_pos": 10288581, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031026.1", "url": "https://www.ensembl.org/id/ENSGALT00010031026.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018034.1", "url": "https://www.ensembl.org/id/ENSGALP00010018034.1" } ] } }, { "isoform_ac": "F1N9Q3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHL9/entry#F1N9Q3-1", "sequence": { "sequence": "MFGIQESIQRSGSSMKEEPLGAGMNAVRTWMQGAGVLDASTAAQSGVGLARAHFEKQPPSNLRKSNFFHFVLALYDRQGQPVEIERTAFVGFVEKEKEANSEKTNNGIHYRLQLLYSNGIRTEQDFYVRLIDSMTKQAIVYEGQDKNPEMCRVLLTHEIMCSRCCDKKSCGNRNETPSDPVIIDRFFLKFFLKCNQNCLKNAGNPRDMRRFQVVVSTTVNVDGHVLAVSDNMFVHNNSKHGRRARRLDPSEGTPSYLEHAATPCIKAISPSEGWTTGGATVIIIGDNFFDGLQVIFGTMLVWSELITPHAIRVQTPPRHIPGVVEVTLSYKSKQFCKGTPGRFIYTALNEPTIDYGFQRLQKVIPRHPGDPERLPKEVILKRAADLVEALYGMPHNNQEIILKRAADIAEALYSVPRNHNQLPALANTSVHAGMMGVNSFSGQLAVNVSEASQATSQGFTRNSSSVSPHGYVPSTTPQQTNYNSVTTSMNGYGNAGMSNLGGSPTFLNGSAANSPYAIVPSSPTMASSTSLPSNCSSSSGIFSFSPANMVSAVKQKSAFAPVVRPQTSPPPTCTSTNGNSLQDQSFVDSSKYSTAGSLQGLAFS", "length": 604, "header": "tr|F1N9Q3-1|F1N9Q3_CHICK Computationally mapped isoform of Transcription factor COE1 OS=Gallus gallus OX=9031 GN=EBF1 PE=3 SV=4 CANONICAL=A0A8V0YHL9-1" }, "locus": { "chromosome": "13", "start_pos": 10543141, "end_pos": 10288581, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031020.1", "url": "https://www.ensembl.org/id/ENSGALT00010031020.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018031.1", "url": "https://www.ensembl.org/id/ENSGALP00010018031.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 253, "start_aa": "Thr", "end_pos": 253, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr253", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "EBF1 acts as a powerful repressor of Blimp-1 gene expression in immature B cells.", "journal": "Biochemical and biophysical research communications", "date": "2012-06-15", "authors": "Kikuchi Hidehiko, Nakayama Masami, Takami Yasunari, Kuribayashi Futoshi, Nakayama Tatsuo", "evidence": [ { "database": "RefSeq", "id": "NP_001384585", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384585" } ], "reference": [ { "type": "PubMed", "id": "22634309", "url": "https://glygen.org/publication/PubMed/22634309" } ] }, { "title": "Regulation of chick early B-cell factor-1 gene expression in feather development.", "journal": "Acta histochemica", "date": "2014-05", "authors": "El-Magd Mohammed Abu, Sayed-Ahmed Ahmed, Awad Ashraf, Shukry Mustafa", "evidence": [ { "database": "RefSeq", "id": "NP_001384585", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384585" } ], "reference": [ { "type": "PubMed", "id": "24365066", "url": "https://glygen.org/publication/PubMed/24365066" } ] }, { "title": "Protein kinase C\u03b8 gene expression is oppositely regulated by GCN5 and EBF1 in immature B cells.", "journal": "FEBS letters", "date": "2014-05-02", "authors": "Kikuchi Hidehiko, Nakayama Masami, Kuribayashi Futoshi, Imajoh-Ohmi Shinobu, Nishitoh Hideki, Takami Yasunari, Nakayama Tatsuo", "evidence": [ { "database": "RefSeq", "id": "NP_001384585", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384585" } ], "reference": [ { "type": "PubMed", "id": "24657615", "url": "https://glygen.org/publication/PubMed/24657615" } ] }, { "title": "The effect of RA on the chick Ebf1-3 genes expression in somites and pharyngeal arches.", "journal": "Development genes and evolution", "date": "2014-12", "authors": "El-Magd Mohammed Abu, Saleh Ayman A, El-Aziz Reda M Abd, Salama Mohammed F", "evidence": [ { "database": "RefSeq", "id": "NP_001384585", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384585" } ], "reference": [ { "type": "PubMed", "id": "25331756", "url": "https://glygen.org/publication/PubMed/25331756" } ] }, { "title": "Shh regulates chick Ebf1 gene expression in somite development.", "journal": "Gene", "date": "2015-01-01", "authors": "El-Magd Mohammed Abu, Allen Steve, McGonnell Imelda, Mansour Ali A, Otto Anthony, Patel Ketan", "evidence": [ { "database": "RefSeq", "id": "NP_001384585", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384585" } ], "reference": [ { "type": "PubMed", "id": "25455103", "url": "https://glygen.org/publication/PubMed/25455103" } ] }, { "title": "Expression and function of Ebf1 gene during chondrogenesis in chick embryo limb buds.", "journal": "Gene", "date": "2021-11-30", "authors": "El-Magd Mohammed A, Abdelfattah-Hassan Ahmed, Elsisy Rasha A, Hawsawi Yousef M, Oyouni Atif A, Al-Amer Osama M, El-Shetry Eman S", "evidence": [ { "database": "RefSeq", "id": "NP_001384585", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384585" } ], "reference": [ { "type": "PubMed", "id": "34384862", "url": "https://glygen.org/publication/PubMed/34384862" } ] } ], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A286ZSS0-1", "protein_name": "Transcription factor COE1", "gene_name": "EBF1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MFGIQESIQRSGSSMKEEPLGSGMNAVRTWMQGAGVLDANTAAQSGVGLARAHFEKQPPSNLRKSNFFHFVLALYDRQGQPVEIERTAFVGFVEKEKEANSEKTNNGIHYRLQLLYSNGIRTEQDFYVRLIDSMTKQAIVYEGQDKNPEMCRVLLTHEIMCSRCCDKKSCGNRNETPSDPVIIDRFFLKFFLKCNQNCLKNAGNPRDMRRFQVVVSTTVNVDGHVLAVSDNMFVHNNSKHGRRARRLDPSEGTPSYLEHATPCIKAISPSEGWTTGGATVIIIGDNFFDGLQVIFGTMLVWSELITPHAIRVQTPPRHIPGVVEVTLSYKSKQFCKGTPGRFIYTALNEPTIDYGFQRLQKVIPRHPGDPERLPKEVILKRAADLVEALYGMPHNNQEIILKRAADIAEALYSVPRNHSQLPALTNTSVHAGMMGVNSFSGQLAVNVSEASQATNQGFTRNSSSVSPHGYVPSTTPQQTNYNSVTTSMNGYGTAAMSNLGGSPTFLNGSAANSPYAIVPSSPTMASSTSLPSNCSSSSGIFSFSPANMVSAVKQKSAFAPVVRPQTSPPPTCTSTNGNSLQAISGMIVPPM", "length": 591 }, "evidence": [ { "id": "A0A8V0YHL9", "url": "https://omabrowser.org/oma/group/A0A8V0YHL9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P56721-1", "protein_name": "Transcription factor collier", "gene_name": "kn", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MEWGRKLYPSAVSGPRSAGGLMFGLPPTAAVDMNQPRGPMTSLKEEPLGSRWAMQPVVDQSNLGIGRAHFEKQPPSNLRKSNFFHFVIALYDRAGQPIEIERTAFIGFIEKDSESDATKTNNGIQYRLQLLYANGARQEQDIFVRLIDSVTKQAIIYEGQDKNPEMCRVLLTHEVMCSRCCDKKSCGNRNETPSDPVIIDRFFLKFFLKCNQNCLKNAGNPRDMRRFQVVISTQVAVDGPLLAISDNMFVHNNSKHGRRAKRLDTTEGTGNTSLSISGHPLAPDSTYDGLYPPLPVATPCIKAISPSEGWTTGGATVIIVGDNFFDGLQVVFGTMLVWSELITSHAIRVQTPPRHIPGVVEVTLSYKSKQFCKGSPGRFVYVSALNEPTIDYGFQRLQKLIPRHPGDPEKLQKEIILKRAADLVEALYSMPRSPGGSTGFNSYAGQLAVSVQDGSGQWTEDDYQRAQSSSVSPRGGYCSSASTPHSSGGSYGATAASAAVAATANGYAPAPNMGTLSSSPGSVFNSTSMSAVSSTWHQAFVQHHHAATAHPHHHYPHPHQPWHNPAVSAATAAAV", "length": 575 }, "evidence": [ { "id": "A0A8V0YHL9", "url": "https://omabrowser.org/oma/group/A0A8V0YHL9/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q07802-1", "protein_name": "Transcription factor COE1", "gene_name": "Ebf1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFGIQESIQRSGSSMKEEPLGSGMNAVRTWMQGAGVLDANTAAQSGVGLARAHFEKQPPSNLRKSNFFHFVLALYDRQGQPVEIERTAFVGFVEKEKEANSEKTNNGIHYRLQLLYSNGIRTEQDFYVRLIDSMTKQAIVYEGQDKNPEMCRVLLTHEIMCSRCCDKKSCGNRNETPSDPVIIDRFFLKFFLKCNQNCLKNAGNPRDMRRFQVVVSTTVNVDGHVLAVSDNMFVHNNSKHGRRARRLDPSEGTPSYLEHATPCIKAISPSEGWTTGGATVIIIGDNFFDGLQVIFGTMLVWSELITPHAIRVQTPPRHIPGVVEVTLSYKSKQFCKGTPGRFIYTALNEPTIDYGFQRLQKVIPRHPGDPERLPKEVILKRAADLVEALYGMPHNNQEIILKRAADIAEALYSVPRNHNQLPALANTSVHAGMMGVNSFSGQLAVNVSEASQATNQGFTRNSSSVSPHGYVPSTTPQQTNYNSVTTSMNGYGSAAMSNLGGSPTFLNGSAANSPYAIVPSSPTMASSTSLPSNCSSSSGIFSFSPANMVSAVKQKSAFAPVVRPQTSPPPTCTSTNGNSLQAISGMIVPPM", "length": 591 }, "evidence": [ { "id": "A0A8V0YHL9", "url": "https://omabrowser.org/oma/group/A0A8V0YHL9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q63398-1", "protein_name": "Transcription factor COE1", "gene_name": "Ebf1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFGIQESIQRSGSSMKEEPLGSGMNAVRTWMQGAGVLDANTAAQSGVGLARAHFEKQPPSNLRKSNFFHFVLALYDRQGQPVEIERTAFVGFVEKEKEANSEKTNNGIHYRLQLLYSNGIRTEQDFYVRLIDSMTKQAIVYEGQDKNPEMCRVLLTHEIMCSRCCDKKSCGNRNETPSDPVIIDRFFLKFFLKCNQNCLKNAGNPRDMRRFQVVVSTTVNVDGHVLAVSDNMFVHNNSKHGRRARRLDPSEAATPCIKAISPSEGWTTGGATVIIIGDNFFDGLQVIFGTMLVWSELITPHAIRVQTPPRHIPGVVEVTLSYKSKQFCKGTPGRFIYTALNEPTIDYGFQRLQKVIPRHPGDPERLPKEVILKRAADLVEALYGMPHNNQEIILKRAADIAEALYSVPRNHNQLPALANTSVHAGMMGVNSFSGQLAVNVSEASQATNQGFTRNSSSVSPHGYVPSTTPQQTNYNSVTTSMNGYGSAAMSNLGGSPTFLNGSAANSPYAIVPSSPTMASSTSLPSNCSSSSGIFSFSPANMVSAVKQKSAFAPVVRPQTSPPPTCTSTNGNSLQAISGMIVPPM", "length": 584 }, "evidence": [ { "id": "A0A8V0YHL9", "url": "https://omabrowser.org/oma/group/A0A8V0YHL9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9UH73-1", "protein_name": "Transcription factor COE1", "gene_name": "EBF1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MFGIQESIQRSGSSMKEEPLGSGMNAVRTWMQGAGVLDANTAAQSGVGLARAHFEKQPPSNLRKSNFFHFVLALYDRQGQPVEIERTAFVGFVEKEKEANSEKTNNGIHYRLQLLYSNGIRTEQDFYVRLIDSMTKQAIVYEGQDKNPEMCRVLLTHEIMCSRCCDKKSCGNRNETPSDPVIIDRFFLKFFLKCNQNCLKNAGNPRDMRRFQVVVSTTVNVDGHVLAVSDNMFVHNNSKHGRRARRLDPSEGTPSYLEHATPCIKAISPSEGWTTGGATVIIIGDNFFDGLQVIFGTMLVWSELITPHAIRVQTPPRHIPGVVEVTLSYKSKQFCKGTPGRFIYTALNEPTIDYGFQRLQKVIPRHPGDPERLPKEVILKRAADLVEALYGMPHNNQEIILKRAADIAEALYSVPRNHNQLPALANTSVHAGMMGVNSFSGQLAVNVSEASQATNQGFTRNSSSVSPHGYVPSTTPQQTNYNSVTTSMNGYGSAAMSNLGGSPTFLNGSAANSPYAIVPSSPTMASSTSLPSNCSSSSGIFSFSPANMVSAVKQKSAFAPVVRPQTSPPPTCTSTNGNSLQAISGMIVPPM", "length": 591 }, "evidence": [ { "id": "A0A8V0YHL9", "url": "https://omabrowser.org/oma/group/A0A8V0YHL9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHL9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHL9" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHL9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHL9" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHL9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHL9" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHL9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHL9" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHL9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHL9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHL9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHL9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHL9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHL9" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHL9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHL9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 174, "end_pos": 176, "annotation": "n_glycosylation_sequon" }, { "start_pos": 236, "end_pos": 238, "annotation": "n_glycosylation_sequon" }, { "start_pos": 427, "end_pos": 429, "annotation": "n_glycosylation_sequon" }, { "start_pos": 447, "end_pos": 449, "annotation": "n_glycosylation_sequon" }, { "start_pos": 462, "end_pos": 464, "annotation": "n_glycosylation_sequon" }, { "start_pos": 508, "end_pos": 510, "annotation": "n_glycosylation_sequon" }, { "start_pos": 534, "end_pos": 536, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YHL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHL9" }, { "id": "SM00429", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00429" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "IPT/TIG", "eco_id": "ECO_0000259", "start_pos": 262, "end_pos": 346, "start_aa": "Thr", "end_aa": "Thr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 253 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 174, "end_pos": 176 }, { "start_pos": 236, "end_pos": 238 }, { "start_pos": 427, "end_pos": 429 }, { "start_pos": 447, "end_pos": 449 }, { "start_pos": 462, "end_pos": 464 }, { "start_pos": 508, "end_pos": 510 }, { "start_pos": 534, "end_pos": 536 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 6 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8V0YHL7-1", "uniprot_ac": "A0A8V0YHL7", "uniprot_id": "A0A8V0YHL7_CHICK", "mass": { "chemical_mass": 29244.0, "monoisotopic_mass": 29244.0 }, "refseq": {}, "gene_names": [ { "name": "RNF114", "type": "recommended", "evidence": [ { "id": "A0A8V0YHL7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHL7" } ] } ], "protein_names": [ { "name": "RING-type E3 ubiquitin transferase", "type": "recommended", "evidence": [ { "id": "A0A8V0YHL7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHL7/entry#names_and_taxonomy" } ] }, { "name": "2.3.2.27", "type": "synonym", "evidence": [ { "id": "A0A8V0YHL7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHL7/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHL7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHL7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RNF114", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHL7", "locus": { "chromosome": "20", "start_pos": 14138636, "end_pos": 14144425, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013119", "url": 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"http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46016:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05605", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05605", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF18574", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18574", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-983168", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983168", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YHL7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHL7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHL7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHL7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "RQVTPPSARTLPSTTPPSRGSALGWGCGCVGAASWLAAGRWRWRAEGTVVCIPPSRGRTCCHASPAPCALRCSRVPFGCPADTFCTPCLQECLKPKKPVCGVCRGVLTAGSRALDLEQLIESTETACSGCGKKMFLSKMRSHAASCSKYQNYIMEGVKAVTKEPVHNARNFPNRFTFPCPYCSEKNFDQEGLVEHCKTLHSMDARQVVCPICASMPWGDPNYRSANFMEHLQRRHRFSYDTFVDYDADEDDTMAQVLMRSLRDK", "length": 264, "header": "tr|A0A8V0YHL7-1|A0A8V0YHL7_CHICK Isoform 1 of RING-type E3 ubiquitin transferase OS=Gallus gallus OX=9031 GN=RNF114 PE=1 SV=1 CANONICAL=A0A8V0YHL7-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YHL7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHL7/entry#A0A8V0YHL7-1", "sequence": { "sequence": "RQVTPPSARTLPSTTPPSRGSALGWGCGCVGAASWLAAGRWRWRAEGTVVCIPPSRGRTCCHASPAPCALRCSRVPFGCPADTFCTPCLQECLKPKKPVCGVCRGVLTAGSRALDLEQLIESTETACSGCGKKMFLSKMRSHAASCSKYQNYIMEGVKAVTKEPVHNARNFPNRFTFPCPYCSEKNFDQEGLVEHCKTLHSMDARQVVCPICASMPWGDPNYRSANFMEHLQRRHRFSYDTFVDYDADEDDTMAQVLMRSLRDK", "length": 264, "header": "tr|A0A8V0YHL7-1|A0A8V0YHL7_CHICK Isoform 1 of RING-type E3 ubiquitin transferase OS=Gallus gallus OX=9031 GN=RNF114 PE=1 SV=1 CANONICAL=A0A8V0YHL7-1" }, "locus": { "chromosome": "20", "start_pos": 14144402, "end_pos": 14141046, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031451.1", "url": "https://www.ensembl.org/id/ENSGALT00010031451.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018361.1", "url": "https://www.ensembl.org/id/ENSGALP00010018361.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "R-GGA-983168", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983168", "resource": "Reactome", "description": "Antigen processing: Ubiquitination & Proteasome degradation" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHL7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHL7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHL7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHL7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "protein polyubiquitination", "id": "GO:0000209", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000209", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHL7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHL7" } ], "pmid": "" }, { "name": "ubiquitin-dependent protein catabolic process", "id": "GO:0006511", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006511", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHL7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHL7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-GGA-983140", "name": "Transfer of Ub from E2 to substrate and release of E2", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0X324-1", "A0A8V0XEM6-1", "A0A8V0XJC4-1", "A0A8V0XQR1-1", "A0A8V1AC19-1", "A0A8V1AC55-1", "A0A8V1AKB8-1", "A0A8V1ALH0-1", "F1NL19-1", "F1NRC6-1", "F1NTZ8-1", "A0A8V0YHL7-1", "A0A8V0YPW4-1", "A0A8V0YRM6-1", "A0A8V0YV22-1", "A0A8V0YVP3-1", "A0A8V0Z2L5-1", "F1NL77-1", "E1C982-1", "A0A3Q2UC96-1", "Q5ZKX6-1", "Z4YJC3-1", "A0A8V0XQU7-1", "A0A8V0Y5C9-1", "A0A8V1AL09-1", "A0A8V1AML5-1", "A0A8V1AP69-1", "F1NVY8-1", "R4GIV8-1", "A0A8V0ZJ49-1", "A0A8V0ZJV9-1", "A0A8V0ZL18-1", "A0A8V0ZM17-1", "A0A8V0ZSH4-1", "A0A8V0ZVX3-1", "A0A8V0ZW26-1", "A0A8V1A0Z6-1", "A0A8V0ZZH3-1", "A0A8V1A052-1", "A0A8V1A0X2-1", "A0A8V1A1I4-1", "A0A8V1A2W7-1", "A0A8V1A5P4-1", "A0A8V1A7T1-1", "A0A8V0XTY5-1", "A0A8V0Y5B5-1", "A0A8V0YL05-1", "A0A8V0Z082-1", "A0A8V0ZS27-1", "A0A8V1A9M0-1", "E1BZ35-1", "E1C3Q9-1", "F1NC08-1", "F1P2G0-1", "A0A8V0YY10-1", "A0A8V0YYC5-1", "A0A8V0Z1W7-1", "A0A8V0Z4C8-1", "A0A8V0Z596-1", "A0A1D5P284-1", "A0A8V0ZF21-1", "A0A3Q2U2G8-1", "A0A8V1A4H7-1", "A0A8V1A1N8-1", "A0A8V1A233-1", "A0A8V1A7P9-1", "A0A8V1ACU3-1", "A0A8V0ZSA3-1", "E1C656-1", "A0A8V0Y0Q7-1", "A0A8V0Y059-1", "A0A8V0Y5C7-1", "A0A8V0YCS7-1", "A0A8V0YDQ1-1", "A0A8V0YFD9-1", "A0A8V0YGF4-1", "A0A8V0YJK8-1", "A0A8V0YLY7-1", "A0A1D5NVE2-1", "A0A8V0ZKK3-1", "A0A8V0ZKQ3-1" ], "evidence": [ { "id": "R-GGA-983140", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983140" } ] }, { "id": "R-GGA-983147", "name": "Release of E3 from polyubiquitinated substrate", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XEM6-1", "A0A8V0XJC4-1", "A0A8V1AC55-1", "A0A8V1AKB8-1", "A0A8V1ALH0-1", "F1NRC6-1", "F1NTZ8-1", "A0A8V0YHL7-1", "A0A8V0YRM6-1", "A0A8V0YV22-1", "A0A8V0YVP3-1", "A0A8V0Z2L5-1", "F1NL77-1", "E1C982-1", "A0A3Q2UC96-1", "Z4YJC3-1", "A0A8V0XQU7-1", "A0A8V0Y5C9-1", "A0A8V1AL09-1", "A0A8V1AML5-1", "A0A8V1AP69-1", "F1NVY8-1", "A0A8V0ZJ49-1", "A0A8V0ZJV9-1", "A0A8V0ZL18-1", "A0A8V0ZM17-1", "A0A8V0ZSH4-1", "A0A8V0ZVX3-1", "A0A8V0ZW26-1", "A0A8V1A0Z6-1", "A0A8V0ZZH3-1", "A0A8V1A0X2-1", "A0A8V1A2W7-1", "A0A8V1A7T1-1", "A0A8V0XTY5-1", "A0A8V0Y5B5-1", "A0A8V0YL05-1", "A0A8V0ZS27-1", "A0A8V1A9M0-1", "E1BZ35-1", "E1C3Q9-1", "F1NC08-1", "F1P2G0-1", "A0A8V0YYC5-1", "A0A8V0Z4C8-1", "A0A8V0Z596-1", "A0A1D5P284-1", "A0A8V0ZF21-1", "A0A3Q2U2G8-1", "A0A8V1A1N8-1", "A0A8V1A233-1", "A0A8V1A7P9-1", "A0A8V0ZSA3-1", "E1C656-1", "A0A8V0Y0Q7-1", "A0A8V0Y5C7-1", "A0A8V0YCS7-1", "A0A8V0YDQ1-1", "A0A8V0YGF4-1", "A0A8V0YJK8-1", "A0A8V0YLY7-1", "A0A8V0ZKK3-1", "A0A8V0ZKQ3-1" ], "evidence": [ { "id": "R-GGA-983147", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983147" } ] }, { "id": "R-GGA-983156", "name": "Polyubiquitination of substrate", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0X324-1", "A0A8V0XEM6-1", "A0A8V0XJC4-1", "A0A8V0XQR1-1", "A0A8V1AC19-1", "A0A8V1AC55-1", "A0A8V1AKB8-1", "A0A8V1ALH0-1", "F1NL19-1", "F1NRC6-1", "F1NTZ8-1", "A0A8V0YHL7-1", "A0A8V0YPW4-1", "A0A8V0YRM6-1", "A0A8V0YV22-1", "A0A8V0YVP3-1", "A0A8V0Z2L5-1", "F1NL77-1", "E1C982-1", "A0A3Q2UC96-1", "Q5ZKX6-1", "Z4YJC3-1", "A0A8V0XQU7-1", "A0A8V0Y5C9-1", "A0A8V1AL09-1", "A0A8V1AML5-1", "A0A8V1AP69-1", "F1NVY8-1", "R4GIV8-1", "A0A8V0ZJ49-1", "A0A8V0ZJV9-1", "A0A8V0ZL18-1", "A0A8V0ZM17-1", "A0A8V0ZSH4-1", "A0A8V0ZVX3-1", "A0A8V0ZW26-1", "A0A8V1A0Z6-1", "A0A8V0ZZH3-1", "A0A8V1A052-1", "A0A8V1A0X2-1", "A0A8V1A1I4-1", "A0A8V1A2W7-1", "A0A8V1A5P4-1", "A0A8V1A7T1-1", "A0A8V0XTY5-1", "A0A8V0Y5B5-1", "A0A8V0YL05-1", "A0A8V0Z082-1", "A0A8V0ZS27-1", "A0A8V1A9M0-1", "E1BZ35-1", "E1C3Q9-1", "F1NC08-1", "F1P2G0-1", "A0A8V0YY10-1", "A0A8V0YYC5-1", "A0A8V0Z1W7-1", "A0A8V0Z4C8-1", "A0A8V0Z596-1", "A0A1D5P284-1", "A0A8V0ZF21-1", "A0A3Q2U2G8-1", "A0A8V1A4H7-1", "A0A8V1A1N8-1", "A0A8V1A233-1", "A0A8V1A7P9-1", "A0A8V1ACU3-1", "A0A8V0ZSA3-1", "E1C656-1", "A0A8V0Y0Q7-1", "A0A8V0Y059-1", "A0A8V0Y5C7-1", "A0A8V0YCS7-1", "A0A8V0YDQ1-1", "A0A8V0YFD9-1", "A0A8V0YGF4-1", "A0A8V0YJK8-1", "A0A8V0YLY7-1", "A0A1D5NVE2-1", "A0A8V0ZKK3-1", "A0A8V0ZKQ3-1" ], "evidence": [ { "id": "R-GGA-983156", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983156" } ] }, { "id": "R-GGA-983157", "name": "Interaction of E3 with substrate and E2-Ub complex", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0X324-1", "A0A8V0XEM6-1", "A0A8V0XJC4-1", "A0A8V0XQR1-1", "A0A8V1AC19-1", "A0A8V1AC55-1", "A0A8V1AKB8-1", "A0A8V1ALH0-1", "F1NL19-1", "F1NRC6-1", "F1NTZ8-1", "A0A8V0YHL7-1", "A0A8V0YPW4-1", "A0A8V0YRM6-1", "A0A8V0YV22-1", "A0A8V0YVP3-1", "A0A8V0Z2L5-1", "F1NL77-1", "E1C982-1", "A0A3Q2UC96-1", "Q5ZKX6-1", "Z4YJC3-1", "A0A8V0XQU7-1", "A0A8V0Y5C9-1", "A0A8V1AL09-1", "A0A8V1AML5-1", "A0A8V1AP69-1", "F1NVY8-1", "R4GIV8-1", "A0A8V0ZJ49-1", "A0A8V0ZJV9-1", "A0A8V0ZL18-1", "A0A8V0ZM17-1", "A0A8V0ZSH4-1", "A0A8V0ZVX3-1", "A0A8V0ZW26-1", "A0A8V1A0Z6-1", "A0A8V0ZZH3-1", "A0A8V1A052-1", "A0A8V1A0X2-1", "A0A8V1A1I4-1", "A0A8V1A2W7-1", "A0A8V1A5P4-1", "A0A8V1A7T1-1", "A0A8V0XTY5-1", "A0A8V0Y5B5-1", "A0A8V0YL05-1", "A0A8V0Z082-1", "A0A8V0ZS27-1", "A0A8V1A9M0-1", "E1BZ35-1", "E1C3Q9-1", "F1NC08-1", "F1P2G0-1", "A0A8V0YY10-1", "A0A8V0YYC5-1", "A0A8V0Z1W7-1", "A0A8V0Z4C8-1", "A0A8V0Z596-1", "A0A1D5P284-1", "A0A8V0ZF21-1", "A0A3Q2U2G8-1", "A0A8V1A4H7-1", "A0A8V1A1N8-1", "A0A8V1A233-1", "A0A8V1A7P9-1", "A0A8V1ACU3-1", "A0A8V0ZSA3-1", "E1C656-1", "A0A8V0Y0Q7-1", "A0A8V0Y059-1", "A0A8V0Y5C7-1", "A0A8V0YCS7-1", "A0A8V0YDQ1-1", "A0A8V0YFD9-1", "A0A8V0YGF4-1", "A0A8V0YJK8-1", "A0A8V0YLY7-1", "A0A1D5NVE2-1", "A0A8V0ZKK3-1", "A0A8V0ZKQ3-1" ], "evidence": [ { "id": "R-GGA-983157", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983157" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A1D5NVE2", "gene_name": "UBE2Q1", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A1D5NVE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NVE2" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A1D5NVE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NVE2" } ] } ] }, { "uniprot_ac": "A0A1D5P284", "gene_name": "UBR2", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A1D5P284", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P284" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A1D5P284", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P284" } ] } ] }, { "uniprot_ac": "A0A3Q2U2G8", "gene_name": "TRIM9", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A3Q2U2G8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U2G8" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A3Q2U2G8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U2G8" } ] } ] }, { "uniprot_ac": "A0A3Q2UC96", "gene_name": "NEDD4L", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A3Q2UC96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UC96" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A3Q2UC96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UC96" } ] } ] }, { "uniprot_ac": "A0A8V0X324", "gene_name": "UBE2E1", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V0X324", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X324" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V0X324", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X324" } ] } ] }, { "uniprot_ac": "A0A8V0XEM6", "gene_name": "HERC2", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0XEM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEM6" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0XEM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEM6" } ] } ] }, { "uniprot_ac": "A0A8V0XJC4", "gene_name": "UBE3D", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0XJC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XJC4" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0XJC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XJC4" } ] } ] }, { "uniprot_ac": "A0A8V0XQR1", "gene_name": "UBE2H", "activity": [ { "ec_number": "2.3.2.24", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E1 ubiquitin-activating enzyme]-L-cysteine + N(6)-monoubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0XQR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQR1" } ] }, { "ec_number": "2.3.2.24", "activity": "", "evidence": [ { "id": "A0A8V0XQR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQR1" } ] } ] }, { "uniprot_ac": "A0A8V0XQU7", "gene_name": "RNF6", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0XQU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQU7" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0XQU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQU7" } ] } ] }, { "uniprot_ac": "A0A8V0XTY5", "gene_name": "SH3RF1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0XTY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XTY5" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0XTY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XTY5" } ] } ] }, { "uniprot_ac": "A0A8V0Y059", "gene_name": "UBE2D1", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V0Y059", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y059" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V0Y059", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y059" } ] } ] }, { "uniprot_ac": "A0A8V0Y0Q7", "gene_name": "RNF144B", "activity": [ { "ec_number": "2.3.2.31", "activity": "[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-N(6)-ubiquitinyl-L-lysine.", "evidence": [ { "id": "A0A8V0Y0Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y0Q7" } ] }, { "ec_number": "2.3.2.31", "activity": "", "evidence": [ { "id": "A0A8V0Y0Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y0Q7" } ] } ] }, { "uniprot_ac": "A0A8V0Y5B5", "gene_name": "LTN1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0Y5B5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5B5" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0Y5B5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5B5" } ] } ] }, { "uniprot_ac": "A0A8V0Y5C7", "gene_name": "CBLL1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0Y5C7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5C7" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0Y5C7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5C7" } ] } ] }, { "uniprot_ac": "A0A8V0Y5C9", "gene_name": "HERC3", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0Y5C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5C9" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0Y5C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5C9" } ] } ] }, { "uniprot_ac": "A0A8V0YCS7", "gene_name": "RNF19A", "activity": [ { "ec_number": "2.3.2.31", "activity": "[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-N(6)-ubiquitinyl-L-lysine.", "evidence": [ { "id": "A0A8V0YCS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCS7" } ] }, { "ec_number": "2.3.2.31", "activity": "", "evidence": [ { "id": "A0A8V0YCS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCS7" } ] } ] }, { "uniprot_ac": "A0A8V0YDQ1", "gene_name": "WWP1", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YDQ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDQ1" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0YDQ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDQ1" } ] } ] }, { "uniprot_ac": "A0A8V0YFD9", "gene_name": "UBE2D2", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V0YFD9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFD9" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V0YFD9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFD9" } ] } ] }, { "uniprot_ac": "A0A8V0YGF4", "gene_name": "MYLIP", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YGF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGF4" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0YGF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGF4" } ] } ] }, { "uniprot_ac": "A0A8V0YHL7", "gene_name": "RNF114", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YHL7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHL7" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0YHL7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHL7" } ] } ] }, { "uniprot_ac": "A0A8V0YJK8", "gene_name": "RNF14", "activity": [ { "ec_number": "2.3.2.31", "activity": "[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-N(6)-ubiquitinyl-L-lysine.", "evidence": [ { "id": "A0A8V0YJK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJK8" } ] }, { "ec_number": "2.3.2.31", "activity": "", "evidence": [ { "id": "A0A8V0YJK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJK8" } ] } ] }, { "uniprot_ac": "A0A8V0YL05", "gene_name": "UBE3A", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YL05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL05" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0YL05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL05" } ] } ] }, { "uniprot_ac": "A0A8V0YLY7", "gene_name": "MKRN4P", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YLY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLY7" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0YLY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLY7" } ] } ] }, { "uniprot_ac": "A0A8V0YPW4", "gene_name": "UBE2J2", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V0YPW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPW4" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V0YPW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPW4" } ] } ] }, { "uniprot_ac": "A0A8V0YRM6", "gene_name": "RNF130", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YRM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRM6" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0YRM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRM6" } ] } ] }, { "uniprot_ac": "A0A8V0YV22", "gene_name": "RNF4", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YV22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YV22" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0YV22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YV22" } ] } ] }, { "uniprot_ac": "A0A8V0YVP3", "gene_name": "RBBP6", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YVP3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YVP3" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0YVP3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YVP3" } ] } ] }, { "uniprot_ac": "A0A8V0YY10", "gene_name": "UBE2D3", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V0YY10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YY10" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V0YY10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YY10" } ] } ] }, { "uniprot_ac": "A0A8V0YYC5", "gene_name": "ZNRF2", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YYC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYC5" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0YYC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYC5" } ] } ] }, { "uniprot_ac": "A0A8V0Z082", "gene_name": "UBE2B", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V0Z082", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z082" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V0Z082", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z082" } ] } ] }, { "uniprot_ac": "A0A8V0Z1W7", "gene_name": "UBE2K", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V0Z1W7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1W7" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V0Z1W7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1W7" } ] } ] }, { "uniprot_ac": "A0A8V0Z2L5", "gene_name": "TRIM63", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0Z2L5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2L5" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0Z2L5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2L5" } ] } ] }, { "uniprot_ac": "A0A8V0Z4C8", "gene_name": "MGRN1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0Z4C8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4C8" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0Z4C8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4C8" } ] } ] }, { "uniprot_ac": "A0A8V0Z596", "gene_name": "STUB1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0Z596", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z596" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0Z596", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z596" } ] } ] }, { "uniprot_ac": "A0A8V0ZF21", "gene_name": "DTX3L", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZF21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF21" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0ZF21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF21" } ] } ] }, { "uniprot_ac": "A0A8V0ZJ49", "gene_name": "SMURF1", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZJ49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ49" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0ZJ49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ49" } ] } ] }, { "uniprot_ac": "A0A8V0ZJV9", "gene_name": "MIB2", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZJV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJV9" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0ZJV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJV9" } ] } ] }, { "uniprot_ac": "A0A8V0ZKK3", "gene_name": "UBE3B", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZKK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKK3" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0ZKK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKK3" } ] } ] }, { "uniprot_ac": "A0A8V0ZKQ3", "gene_name": "RNF25", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZKQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKQ3" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0ZKQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKQ3" } ] } ] }, { "uniprot_ac": "A0A8V0ZL18", "gene_name": "HECTD2", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZL18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZL18" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0ZL18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZL18" } ] } ] }, { "uniprot_ac": "A0A8V0ZM17", "gene_name": "UBR1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZM17", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM17" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0ZM17", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM17" } ] } ] }, { "uniprot_ac": "A0A8V0ZS27", "gene_name": "TRIP12", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZS27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS27" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0ZS27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS27" } ] } ] }, { "uniprot_ac": "A0A8V0ZSA3", "gene_name": "HERC4", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZSA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSA3" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0ZSA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSA3" } ] } ] }, { "uniprot_ac": "A0A8V0ZSH4", "gene_name": "RNF111", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZSH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSH4" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0ZSH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSH4" } ] } ] }, { "uniprot_ac": "A0A8V0ZVX3", "gene_name": "NEDD4", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZVX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVX3" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0ZVX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVX3" } ] } ] }, { "uniprot_ac": "A0A8V0ZW26", "gene_name": "ZNRF1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZW26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZW26" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0ZW26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZW26" } ] } ] }, { "uniprot_ac": "A0A8V0ZZH3", "gene_name": "ITCH", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZZH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZH3" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0ZZH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZH3" } ] } ] }, { "uniprot_ac": "A0A8V1A052", "gene_name": "UBE2E3", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V1A052", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A052" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V1A052", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A052" } ] } ] }, { "uniprot_ac": "A0A8V1A0X2", "gene_name": "UBE3C", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1A0X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0X2" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V1A0X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0X2" } ] } ] }, { "uniprot_ac": "A0A8V1A0Z6", "gene_name": "UBE4A", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1A0Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0Z6" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1A0Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0Z6" } ] } ] }, { "uniprot_ac": "A0A8V1A1I4", "gene_name": "UBE2Z", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V1A1I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1I4" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V1A1I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1I4" } ] } ] }, { "uniprot_ac": "A0A8V1A1N8", "gene_name": "HERC1", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1A1N8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1N8" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V1A1N8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1N8" } ] } ] }, { "uniprot_ac": "A0A8V1A233", "gene_name": "RNF220", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1A233", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A233" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1A233", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A233" } ] } ] }, { "uniprot_ac": "A0A8V1A2W7", "gene_name": "RNF41", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1A2W7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2W7" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1A2W7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2W7" } ] } ] }, { "uniprot_ac": "A0A8V1A4H7", "gene_name": "UBE2L3", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V1A4H7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4H7" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V1A4H7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4H7" } ] } ] }, { "uniprot_ac": "A0A8V1A5P4", "gene_name": "UBE2G2", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V1A5P4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5P4" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V1A5P4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5P4" } ] } ] }, { "uniprot_ac": "A0A8V1A7P9", "gene_name": "DCAF1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A7P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P9" } ] } ] }, { "uniprot_ac": "A0A8V1A7T1", "gene_name": "RNF123", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1A7T1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7T1" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1A7T1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7T1" } ] } ] }, { "uniprot_ac": "A0A8V1A9M0", "gene_name": "RNF34", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1A9M0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9M0" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1A9M0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9M0" } ] } ] }, { "uniprot_ac": "A0A8V1AC19", "gene_name": "UBA7", "activity": [ { "ec_number": "6.2.1.45", "activity": "ATP + ubiquitin + [E1 ubiquitin-activating enzyme]-L-cysteine = AMP + diphosphate + S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V1AC19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC19" } ] }, { "ec_number": "6.2.1.45", "activity": "", "evidence": [ { "id": "A0A8V1AC19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC19" } ] } ] }, { "uniprot_ac": "A0A8V1AC55", "gene_name": "SMURF2", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1AC55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC55" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V1AC55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC55" } ] } ] }, { "uniprot_ac": "A0A8V1ACU3", "gene_name": "UBE2O", "activity": [ { "ec_number": "2.3.2.24", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E1 ubiquitin-activating enzyme]-L-cysteine + N(6)-monoubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1ACU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACU3" } ] }, { "ec_number": "2.3.2.24", "activity": "", "evidence": [ { "id": "A0A8V1ACU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACU3" } ] } ] }, { "uniprot_ac": "A0A8V1AKB8", "gene_name": "TRIM32", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1AKB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKB8" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1AKB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKB8" } ] } ] }, { "uniprot_ac": "A0A8V1AL09", "gene_name": "TRIM37", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1AL09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL09" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1AL09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL09" } ] } ] }, { "uniprot_ac": "A0A8V1ALH0", "gene_name": "RNF213", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1ALH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALH0" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1ALH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALH0" } ] } ] }, { "uniprot_ac": "A0A8V1AML5", "gene_name": "TRIM50", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1AML5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AML5" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1AML5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AML5" } ] } ] }, { "uniprot_ac": "A0A8V1AP69", "gene_name": "TRIM58", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1AP69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP69" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1AP69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP69" } ] } ] }, { "uniprot_ac": "E1BZ35", "gene_name": "RNF182", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1BZ35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BZ35" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "E1BZ35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BZ35" } ] } ] }, { "uniprot_ac": "E1C3Q9", "gene_name": "SIAH2", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1C3Q9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C3Q9" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "E1C3Q9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C3Q9" } ] } ] }, { "uniprot_ac": "E1C656", "gene_name": "HACE1", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1C656", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C656" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "E1C656", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C656" } ] } ] }, { "uniprot_ac": "E1C982", "gene_name": "AREL1", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1C982", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C982" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "E1C982", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C982" } ] } ] }, { "uniprot_ac": "F1NC08", "gene_name": "RNF138", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1NC08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NC08" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "F1NC08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NC08" } ] } ] }, { "uniprot_ac": "F1NL19", "gene_name": "CDC34", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "F1NL19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NL19" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "F1NL19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NL19" } ] } ] }, { "uniprot_ac": "F1NL77", "gene_name": "CBLB", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1NL77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NL77" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "F1NL77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NL77" } ] } ] }, { "uniprot_ac": "F1NRC6", "gene_name": "RLIM", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1NRC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NRC6" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "F1NRC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NRC6" } ] } ] }, { "uniprot_ac": "F1NTZ8", "gene_name": "HECW2", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1NTZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NTZ8" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "F1NTZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NTZ8" } ] } ] }, { "uniprot_ac": "F1NVY8", "gene_name": "LNX1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1NVY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NVY8" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "F1NVY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NVY8" } ] } ] }, { "uniprot_ac": "F1P2G0", "gene_name": "SIAH1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1P2G0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P2G0" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "F1P2G0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P2G0" } ] } ] }, { "uniprot_ac": "Q5ZKX6", "gene_name": "UBE2F", "activity": [ { "ec_number": "2.3.2.34", "activity": "[E1 NEDD8-activating enzyme]-S-[NEDD8 protein]-yl-L-cysteine + [E2 NEDD8-conjugating enzyme]-L-cysteine = [E1 NEDD8-activating enzyme]-L-cysteine + [E2 NEDD8-conjugating enzyme]-S-[NEDD8-protein]-yl-L-cysteine.", "evidence": [ { "id": "Q5ZKX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKX6" } ] }, { "ec_number": "2.3.2.34", "activity": "", "evidence": [ { "id": "Q5ZKX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKX6" } ] } ] }, { "uniprot_ac": "R4GIV8", "gene_name": "UBE2R2", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "R4GIV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GIV8" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "R4GIV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GIV8" } ] } ] }, { "uniprot_ac": "Z4YJC3", "gene_name": "TRIM71", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": 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N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "2.3.2.27", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.3.2.27" } ] } ], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { 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record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052535.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process On Mar 1, 2022 this sequence version replaced XP_040556411.1. 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"Protein Classification" ] }, { "id": "PF13908", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13908", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_040556411", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040556411", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YHM0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHM0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHM0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHM0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAGRRRLLLLRCLLLGLLGGGGGQRGGGEYCHGWVDGQGGYHDGFQCPEGFDTAAATICCGSCALRYCCAAAEARLEQGGCTNHREPPEPAVSAQPIYVPFLIVGSIFIAFIIVGSLVAVYCCTCLRPKQPSQPIRFSLRSYQTETLPMILPSSSCRAPSRPSSTATSSSSASGSLRRFSLARAEPGCLLPSPPPPYSAGCFPAAHTAHLGSPPGFLQAPPYLGYPDPALGGKGCADLVQS", "length": 241, "header": "tr|A0A8V0YHM0-1|A0A8V0YHM0_CHICK Isoform 1 of Shisa family member 3 OS=Gallus gallus OX=9031 GN=SHISA3 PE=4 SV=1 CANONICAL=A0A8V0YHM0-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YHM0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHM0/entry#A0A8V0YHM0-1", "sequence": { "sequence": "MAGRRRLLLLRCLLLGLLGGGGGQRGGGEYCHGWVDGQGGYHDGFQCPEGFDTAAATICCGSCALRYCCAAAEARLEQGGCTNHREPPEPAVSAQPIYVPFLIVGSIFIAFIIVGSLVAVYCCTCLRPKQPSQPIRFSLRSYQTETLPMILPSSSCRAPSRPSSTATSSSSASGSLRRFSLARAEPGCLLPSPPPPYSAGCFPAAHTAHLGSPPGFLQAPPYLGYPDPALGGKGCADLVQS", "length": 241, "header": "tr|A0A8V0YHM0-1|A0A8V0YHM0_CHICK Isoform 1 of Shisa family member 3 OS=Gallus gallus OX=9031 GN=SHISA3 PE=4 SV=1 CANONICAL=A0A8V0YHM0-1" }, "locus": { "chromosome": "4", "start_pos": 67763530, "end_pos": 67762424, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034731.1", "url": "https://www.ensembl.org/id/ENSGALT00010034731.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020370.1", "url": "https://www.ensembl.org/id/ENSGALP00010020370.1" } ] } } ], "glycosylation": [], "phosphorylation": [], 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"database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHM0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHM0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YHM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHM0" }, { "id": "PF13908", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13908" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Shisa N-terminal", "eco_id": "ECO_0000259", "start_pos": 28, "end_pos": 83, "start_aa": "Gly", "end_aa": "Asn", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YHM2-1", "uniprot_ac": "A0A8V0YHM2", "uniprot_id": "A0A8V0YHM2_CHICK", "mass": { "chemical_mass": 14793.0, "monoisotopic_mass": 14793.0 }, "refseq": { "ac": "XP_004944821", "name": "small integral membrane protein 33", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004944821" }, "gene_names": [ { "name": "LOC101747310", "type": "recommended", "evidence": [ { "id": "A0A8V0YHM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHM2" } ] }, { "name": "LOC101747310", "type": 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##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052544.1) annotated using gene prediction method: Gnomon. 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YHN5-1", "uniprot_ac": "A0A8V0YHN5", "uniprot_id": "A0A8V0YHN5_CHICK", "mass": { "chemical_mass": 34012.0, "monoisotopic_mass": 34012.0 }, "refseq": { "ac": "XP_040551583", "name": "ras association domain-containing protein 3 isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040551583" }, "gene_names": [ { "name": "RASSF3", "type": "recommended", "evidence": [ { "id": "A0A8V0YHN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHN5" } ] }, { "name": "RASSF3", "type": "synonym", "evidence": [ { "id": "XP_040551583", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040551583" } ] } ], "protein_names": [ { "name": "Ras association domain family member 3", "type": "synonym", "evidence": [ { "id": "A0A8V0YHN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHN5/entry#names_and_taxonomy" } ] }, { "name": "ras association domain-containing protein 3 isoform X3", "type": "synonym", "evidence": [ { "id": "XP_040551583", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040551583" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040551583", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040551583" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHN5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHN5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RASSF3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHN5", "locus": { "chromosome": "1", "start_pos": 33894180, "end_pos": 33802608, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013129", "url": "https://www.ensembl.org/id/ENSGALG00010013129" } ] } } ], "crossref": [ { "id": "A0A8V0YHN5", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YHN5", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd17219", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd17219", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd21891", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd21891", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "417828", "url": "https://www.ncbi.nlm.nih.gov/gene/417828", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000159", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000159", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011524", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011524", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029071", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029071", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033614", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033614", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "YCRDLVH", "url": "https://omabrowser.org/oma/group/YCRDLVH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YC64", "url": "https://www.orthodb.org/?gene=A0A8V0YC64", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YHN5", "url": "https://www.orthodb.org/?gene=A0A8V0YHN5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YIJ3", "url": "https://www.orthodb.org/?gene=A0A8V0YIJ3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YKJ5", "url": "https://www.orthodb.org/?gene=A0A8V0YKJ5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22738", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22738", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22738:SF8", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22738:SF8", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00788", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00788", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16517", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16517", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_040551583", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040551583", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YC64", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC64", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YC64-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC64-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHN5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHN5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHN5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHN5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YIJ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIJ3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YIJ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIJ3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YKJ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKJ5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YKJ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKJ5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAIRSDFSKTIRRIARFFYRFPKSLGSSRRRTVKLLWKSTDCKYTCHAHCRDLVHLGCRRNGKLMDCLTAHGTLHGSDSDGQDVQKETEPHVYLSKEEVKEKIQSYNSSVTDKLKMTLNSNGIYTGFIKVQMELCRPITVQSSPGQGPCAHSNNETAFYLPNDCVNTLHISSTNTVREVIEALLKKFFVADNPAKFALYKRCHKEDQVYICKLSDREHPLYLRLVAGPRTEMLSFVLREHETGEVMWEAFSLPELQNFLRILDKEENEQLQILKKRYAAYRDKLEEALGGVWKPG", "length": 295, "header": "tr|A0A8V0YHN5-1|A0A8V0YHN5_CHICK Isoform 1 of Ras association domain family member 3 OS=Gallus gallus OX=9031 GN=RASSF3 PE=4 SV=1 CANONICAL=A0A8V0YHN5-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YC64-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHN5/entry#A0A8V0YC64-1", "sequence": { "sequence": "MRRPGVRSPPPGPSRTSSSGYSSLEEEDSEEYFFTARTSFFRRPPGKTRAAPQDVQKETEPHVYLSKEEVKEKIQSYNSSVTDKLKMTLNSNGIYTGFIKVQMELCRPITVQSSPGQGPCAHSNNETAFYLPNDCVNTLHISSTNTVREVIEALLKKFFVADNPAKFALYKRCHKEDQVYICKLSDREHPLYLRLVAGPRTEMLSFVLREHETGEVMWEAFSLPELQNFLRILDKEENEQLQILKKRYAAYRDKLEEALGGVWKPG", "length": 266, "header": "tr|A0A8V0YC64-1|A0A8V0YC64_CHICK Computationally mapped isoform of Ras association domain family member 3 OS=Gallus gallus OX=9031 GN=RASSF3 PE=4 SV=1 CANONICAL=A0A8V0YHN5-1" }, "locus": { "chromosome": "1", "start_pos": 33891415, "end_pos": 33843221, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031468.1", "url": "https://www.ensembl.org/id/ENSGALT00010031468.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018372.1", "url": "https://www.ensembl.org/id/ENSGALP00010018372.1" } ] } }, { "isoform_ac": "A0A8V0YHN5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHN5/entry#A0A8V0YHN5-1", "sequence": { "sequence": "MAIRSDFSKTIRRIARFFYRFPKSLGSSRRRTVKLLWKSTDCKYTCHAHCRDLVHLGCRRNGKLMDCLTAHGTLHGSDSDGQDVQKETEPHVYLSKEEVKEKIQSYNSSVTDKLKMTLNSNGIYTGFIKVQMELCRPITVQSSPGQGPCAHSNNETAFYLPNDCVNTLHISSTNTVREVIEALLKKFFVADNPAKFALYKRCHKEDQVYICKLSDREHPLYLRLVAGPRTEMLSFVLREHETGEVMWEAFSLPELQNFLRILDKEENEQLQILKKRYAAYRDKLEEALGGVWKPG", "length": 295, "header": "tr|A0A8V0YHN5-1|A0A8V0YHN5_CHICK Isoform 1 of Ras association domain family member 3 OS=Gallus gallus OX=9031 GN=RASSF3 PE=4 SV=1 CANONICAL=A0A8V0YHN5-1" }, "locus": { "chromosome": "1", "start_pos": 33891415, "end_pos": 33802718, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031472.1", "url": "https://www.ensembl.org/id/ENSGALT00010031472.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018376.1", "url": "https://www.ensembl.org/id/ENSGALP00010018376.1" } ] } }, { "isoform_ac": "A0A8V0YIJ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHN5/entry#A0A8V0YIJ3-1", "sequence": { "sequence": "MELLPLPVLLCFITQAREHVDVQKETEPHVYLSKEEVKEKIQSYNSSVTDKLKMTLNSNGIYTGFIKVQMELCRPITVQSSPGQGPCAHSNNETAFYLPNDCVNTLHISSTNTVREVIEALLKKFFVADNPAKFALYKRCHKEDQVYICKLSDREHPLYLRLVAGPRTEMLSFVLREHETGEVMWEAFSLPELQNFLRILDKEENEQLQILKKRYAAYRDKLEEALGGVWKPG", "length": 233, "header": "tr|A0A8V0YIJ3-1|A0A8V0YIJ3_CHICK Computationally mapped isoform of Ras association domain family member 3 OS=Gallus gallus OX=9031 GN=RASSF3 PE=4 SV=1 CANONICAL=A0A8V0YHN5-1" }, "locus": { "chromosome": "1", "start_pos": 33891415, "end_pos": 33868389, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031463.1", "url": "https://www.ensembl.org/id/ENSGALT00010031463.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018369.1", "url": "https://www.ensembl.org/id/ENSGALP00010018369.1" } ] } }, { "isoform_ac": "A0A8V0YKJ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHN5/entry#A0A8V0YKJ5-1", "sequence": { "sequence": "MHRWGGWDLRKPHLGLSYLAELCFGIAPRKSLSRRCREDVPWSAGMDFLTACSIEMLRDVQKETEPHVYLSKEEVKEKIQSYNSSVTDKLKMTLNSNGIYTGFIKVQMELCRPITVQSSPGQGPCAHSNNETAFYLPNDCVNTLHISSTNTVREVIEALLKKFFVADNPAKFALYKRCHKEDQVYICKLSDREHPLYLRLVAGPRTEMLSFVLREHETGEVMWEAFSLPELQNFLRILDKEENEQLQILKKRYAAYRDKLEEALGGVWKPG", "length": 271, "header": "tr|A0A8V0YKJ5-1|A0A8V0YKJ5_CHICK Computationally mapped isoform of Ras association domain family member 3 OS=Gallus gallus OX=9031 GN=RASSF3 PE=4 SV=1 CANONICAL=A0A8V0YHN5-1" }, "locus": { "chromosome": "1", "start_pos": 33891415, "end_pos": 33857364, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031464.1", "url": "https://www.ensembl.org/id/ENSGALT00010031464.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018370.1", "url": "https://www.ensembl.org/id/ENSGALP00010018370.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A286ZZ73-1", "protein_name": "Ras association domain-containing protein 3", "gene_name": "RASSF3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSSGYSSLEEDAEDFFFTARTSFFRRAPQGKPRAGQQDVEKEKETHSYLSKEEIKEKVHKYNLAVTDKLKMTLNSNGIYTGFIKVQMELCKPSQSSPNPGKLAPSSNGYMNTLHISSTNTVGEVIEALLKKFLVTESPTKFALYKRCHREDQVYACKLSDREHPLYLRLVAGPRTDTLSFVLREHEIGEWEAFSLPELQNFLRILDKEEDEQLQNLKERYAAYRHKLEEALGEAWKPG", "length": 238 }, "evidence": [ { "id": "A0A8V0YHN5", "url": "https://omabrowser.org/oma/group/A0A8V0YHN5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0ABI0NSH2-1", "protein_name": "Ras association domain-containing protein 3", "gene_name": "RASSF3", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGTAIYKLSGKINFRVKKTHIPEGKYICHSYCQDLVHLDYPQNGKLPSGMPICEVRHSSQNNPQDVEKEKETHNYLSKEEIKEKVHKYNLAVTDKLKMTLNSNGIYTGFIKVQMELCKPSQTAGKPAPSSNSCMNTLHISSTNTVGEVIEALLKKFLVTESPTKFALYKRCHREDQVYACKLSDREHPLYLRLVAGPRTDTLSFVLREHEIGEWEAFSLPELQNFLRILDKEEDEQLQNLKERYAAYRHKLEEALSQAWKPG", "length": 262 }, "evidence": [ { "id": "A0A8V0YHN5", "url": "https://omabrowser.org/oma/group/A0A8V0YHN5/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "D4ACL6-1", "protein_name": "Ras association domain-containing protein 3", "gene_name": "Rassf3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSSGYSSLEEDAEDFFFTARTSFFRRAPPGKSRSGQPDVEKEKETHNYLSKEEIKEKVHKYNLAVTDKLKMTLNSNGIYTGFIKVQMELCKPAQTPANPSSSGCMNTLHISSTNTVGDVIDALLKKFQVTESPTKFALYKRCHREDQVYACKLSDREHPLYLRLVAGPRTDTLSFVLREHEIGEWEAFSLPELQNFLRILDKEEDEQLQSLKRRYTAYRQKLEEALGEVWKPG", "length": 233 }, "evidence": [ { "id": "A0A8V0YHN5", "url": "https://omabrowser.org/oma/group/A0A8V0YHN5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q86WH2-1", "protein_name": "Ras association domain-containing protein 3", "gene_name": "RASSF3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSSGYSSLEEDAEDFFFTARTSFFRRAPQGKPRSGQQDVEKEKETHSYLSKEEIKEKVHKYNLAVTDKLKMTLNSNGIYTGFIKVQMELCKPPQTSPNSGKLSPSSNGCMNTLHISSTNTVGEVIEALLKKFLVTESPAKFALYKRCHREDQVYACKLSDREHPLYLRLVAGPRTDTLSFVLREHEIGEWEAFSLPELQNFLRILDKEEDEQLQNLKRRYTAYRQKLEEALREVWKPD", "length": 238 }, "evidence": [ { "id": "A0A8V0YHN5", "url": "https://omabrowser.org/oma/group/A0A8V0YHN5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q99P51-1", "protein_name": "Ras association domain-containing protein 3", "gene_name": "Rassf3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSGYSSLEEDEDFFFTARTSFFRRAPPGKSRSGQPDVEKEKETHNYLSKEEIKEKVHKYNSAVTDKLKMTLNSNGIYTGFIKVQMELCKPAQPSPEPSSGGCMNTLHISSTNTVGEVIEALLRKFLVTESPTKFALYKRCHREDQVYACKLSDREHPLYLRLVAGPRTDTLSFVLREHEIGEWEAFSLPELQNFLRILDKEEDEQLQSLKRRYTAYRQKLEEALGEVWKPG", "length": 232 }, "evidence": [ { "id": "A0A8V0YHN5", "url": "https://omabrowser.org/oma/group/A0A8V0YHN5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHN5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHN5" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHN5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHN5" } ], "pmid": "" }, { "name": "microtubule", "id": "GO:0005874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005874", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHN5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHN5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHN5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHN5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHN5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHN5" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHN5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHN5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 107, "end_pos": 109, "annotation": "n_glycosylation_sequon" }, { "start_pos": 154, "end_pos": 156, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YHN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHN5" }, { "id": "PS50200", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50200" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ras-associating", "eco_id": "ECO_0000259", "start_pos": 152, "end_pos": 242, "start_aa": "Ser", "end_aa": "Thr", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0YHN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHN5" }, { "id": "PS50951", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50951" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SARAH", "eco_id": "ECO_0000259", "start_pos": 244, "end_pos": 291, "start_aa": "Glu", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 107, "end_pos": 109 }, { "start_pos": 154, "end_pos": 156 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YHN9-1", "uniprot_ac": "A0A8V0YHN9", "uniprot_id": "A0A8V0YHN9_CHICK", "mass": { "chemical_mass": 71263.0, "monoisotopic_mass": 71263.0 }, "refseq": {}, "gene_names": [ { "name": "ASNSD1", "type": "recommended", "evidence": [ { "id": "A0A8V0YHN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHN9" } ] } ], "protein_names": [ { "name": "Asparagine synthetase domain-containing protein 1", "type": "recommended", "evidence": [ { "id": "A0A8V0YHN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHN9/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHN9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHN9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ASNSD1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHN9", "locus": { "chromosome": "7", "start_pos": 405833, "end_pos": 409334, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012943", "url": "https://www.ensembl.org/id/ENSGALG00010012943" } ] } } ], "crossref": [ { "id": "A0A8V0YHN9", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YHN9", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd01991", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01991", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd03766", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03766", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "423983", "url": "https://www.ncbi.nlm.nih.gov/gene/423983", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001962", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001962", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014729", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014729", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017932", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017932", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029055", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029055", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051857", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051857", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:423983", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423983", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "SVYESCP", "url": "https://omabrowser.org/oma/group/SVYESCP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YHN9", "url": "https://www.orthodb.org/?gene=A0A8V0YHN9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45937", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45937", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45937:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45937:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00733", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00733", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001006509", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006509", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YHN9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHN9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHN9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHN9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MCGICCVVALSSQHTICDYFSKDLHCCLRRRGPDSSQQLIKTVSEPSYECLFSGHVLHLRGLMTPQPLEDVNNNIFLWNGEIFNGVHVGDSENDTEVMFRHLALCSSEADILSLFSSLRGPWSFIYYQASGHSLWFGRDYFGRRSLLWQLSNVSDGAFCLTSVSVNSESCNQCQEVPASGIFKMDLRDCATTKSLSLTLFPWKYKCTEKNEEEIFIDVLDQVSKDLPNHITVVMNESKLCLSAPVIPLNRTISEASVEHVSSDSSETSSVVSLETLQGYLAVEHKRKVVHQFIDVLDEAVKRRVLLLRRGEDEGTGQVQGVSPRKAHVAVLFSGGVDSMVIAALADRHVPLEEPIDLLNVAFMTKEQTKRTGTTKNCIRQEMQLDLHRGEENHKDLDAKMGDDLSCFDVPDRITGRAGLKELEALNPSRTWNFVEINVTLKELKEMRRQFINHLIYPLDTVLDDSIGCAIWFASRGEGYINKQGEMKPYKSPAKVVLTGIGADEQLAGYSRHRICFRKCGPEGLNKELEMELGRISSRNLGRDDRIIGDHGKEARFPFIDEDVVSFLNSLPISEKADLTLPRGVGEKLILRLGAKELGLEAASILPKRAVQFGSRIAKLESNNEKAYHTCSRLKLF", "length": 636, "header": "tr|A0A8V0YHN9-1|A0A8V0YHN9_CHICK Isoform 1 of Asparagine synthetase domain-containing protein 1 OS=Gallus gallus OX=9031 GN=ASNSD1 PE=4 SV=1 CANONICAL=A0A8V0YHN9-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YHN9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHN9/entry#A0A8V0YHN9-1", "sequence": { "sequence": "MCGICCVVALSSQHTICDYFSKDLHCCLRRRGPDSSQQLIKTVSEPSYECLFSGHVLHLRGLMTPQPLEDVNNNIFLWNGEIFNGVHVGDSENDTEVMFRHLALCSSEADILSLFSSLRGPWSFIYYQASGHSLWFGRDYFGRRSLLWQLSNVSDGAFCLTSVSVNSESCNQCQEVPASGIFKMDLRDCATTKSLSLTLFPWKYKCTEKNEEEIFIDVLDQVSKDLPNHITVVMNESKLCLSAPVIPLNRTISEASVEHVSSDSSETSSVVSLETLQGYLAVEHKRKVVHQFIDVLDEAVKRRVLLLRRGEDEGTGQVQGVSPRKAHVAVLFSGGVDSMVIAALADRHVPLEEPIDLLNVAFMTKEQTKRTGTTKNCIRQEMQLDLHRGEENHKDLDAKMGDDLSCFDVPDRITGRAGLKELEALNPSRTWNFVEINVTLKELKEMRRQFINHLIYPLDTVLDDSIGCAIWFASRGEGYINKQGEMKPYKSPAKVVLTGIGADEQLAGYSRHRICFRKCGPEGLNKELEMELGRISSRNLGRDDRIIGDHGKEARFPFIDEDVVSFLNSLPISEKADLTLPRGVGEKLILRLGAKELGLEAASILPKRAVQFGSRIAKLESNNEKAYHTCSRLKLF", "length": 636, "header": "tr|A0A8V0YHN9-1|A0A8V0YHN9_CHICK Isoform 1 of Asparagine synthetase domain-containing protein 1 OS=Gallus gallus OX=9031 GN=ASNSD1 PE=4 SV=1 CANONICAL=A0A8V0YHN9-1" }, "locus": { "chromosome": "7", "start_pos": 409304, "end_pos": 405910, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031056.1", "url": "https://www.ensembl.org/id/ENSGALT00010031056.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018054.1", "url": "https://www.ensembl.org/id/ENSGALP00010018054.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:423983", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423983", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3Q1LZM2-1", "protein_name": "Asparagine synthetase domain-containing protein 1", "gene_name": "ASNSD1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MCGICCAVSFSVEHFSRDLKEDLLCNLKRRGPDSSKQLLRSTVNYQCLFSGHVLHLRGLLTAQPVEDERGNVFLWNGEVFSGIKVEAEENDTQIMFHYLSSCKNESDILSLFSEVQGPWSFIYYQASSHSLWFGRDFFGRRSLLWHFSNLGKSFCLSSVGTQASGVADQWQEVPASGIFRIDLKSASISQSVVLKLYPWKYSSGGDDIRECVHNSLTEISADLPTLVLVAANEAKLYLKDPVVPLNMALPQAAFETHCSSISRSPLTRETLRVFLTDGHTKEVVQQFIGVLSTAVKRRVLCLPRDENLAPSKVLKTSNGKANVAVLFSGGIDSMVIAALADHHIPLDEPIDLLNVAFMTKEKTIPVNFNKKGRKQANHCEMPSEEFSKRAAATAAASPGEQLSVPDRVTGRAGLKELQAANPSRIWNFVEINVSLEELQRLRRTRISHLIQPLDTVLDDSIGCAVWFASRGAGWLVTQDGAQPYQSSAKVVLTGIGADEQLAGYSRHRVRFLAHGLEGLNKEIEMELGRISSRNLGRDDRVISDHGKEARFPFLDENVVSFLNSLPVWEKANLTLPRGIGEKLILRLAAVELGLTASALLPKRALQFGSRIAKMEKNNEKASDKCGRLQIISLENLSVEN", "length": 640 }, "evidence": [ { "id": "A0A8V0YHN9", "url": "https://omabrowser.org/oma/group/A0A8V0YHN9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A8MRC1-1", "protein_name": "Asparagine synthase family protein", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MCGIAIVVCGVRIELSTLSSSLSETETPFERLQVSVEDVKAVLSQRGPDSVGEKTIHLRPNCGQESATLSVVETSEGTYKLEETTSLGELHFIGSTLQLRGTSPIRQPLVDSSGNILAYNGEVFGGIELNSYDNDTEVLLKSLEKAKSLVPDVLSMIKGPWAIIYWQESSRTLWFGKDPFGRRSLLVHSPTVEDPRFLLSSVSPASSVSQGLDTENGNSLHRYWEELPCGVYSISFGVSELCIHGEVTKHEWRNTIWKELIEWERKLVVPRPEDLSTSSLSGVQEDKSVSTSLGFAQTVLVVLKESVRRRTSLHSIYQGDKEAVPVAVLFSGGLDSMILAALLHQCLDPKYEVDLLNVSFDGPNAPDRISAKAGIKELKKIAPFRRWKLVEIDADLSKLGFETKRVMSLINPADTYMDLNIGTALWLAARGDGWIHEDNGNPSVEENNQRVKYKSDARILLVGAGADEQCAGYGRHRTKYRNGSWVALDQEMKLDMQRIWKRNLGRDDRCIADNGKEGRFPFLDEDVIKTLLDIPLWEIADLEQPSGTGDKKILRQVASLLGVHEVAKMPKRAIQFGSRIARESNRKNFGSNRAANQASAGSVRFLAPSH", "length": 610 }, "evidence": [ { "id": "A0A8V0YHN9", "url": "https://omabrowser.org/oma/group/A0A8V0YHN9/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "D3ZWR3-1", "protein_name": "Asparagine synthetase domain-containing protein 1", "gene_name": "Asnsd1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MCGICCSVSFSVEHFSKDLKEDLLYNLRRRGPSSSRQLLKSAVNYQCLFSGHVLHLRGVLTAQPVEDECGNVFLWNGEVFNGVQVEAEDNDTQVMFSSLSACKNESEILSLFSKVHGPWSFIYYQASSHCLWFGRDVFGRRSLLWQFSNLGKSFCLSSVGAQISGGADQWQEVPASGIFQIDLNSAAVSRCVILKLYPWKSISKENVAEECANELTQTPAELPEFVSVVINKANLYLSKPIVPLNKTLPEVPLETQCRNSSSVPGSRETLEILLRDEHTQRIVQQFIDVLSVAVKRRTLCLAREENLASKDVLKTCGKKANIAILFSGGVDSMVIAALADRHIPLDEPIDLLNVAFLPKQKAGLPIPNVERNQQNHCEIPPEESSPSTAVPQGPHDAEVPDRVTGKAGLKELQSVNPSRTWNFVEINVSLEELQKLRRARICHLVQPSDTVLDDSIGCAVWFASRGIGWLVTEDAVQSYKSSAKVILTGIGADEQLAGYSRHRARFQSLGLEGLNEEIAMELGRISSRNLGRDDRVIADHGKEARFPFLDENVVSFLNSLPVWEKVDLALPRGVGEKLILRLAAVELGLSSSALLPKRAIQFGSRIAKLEETNEKASDKCGRLQILP", "length": 627 }, "evidence": [ { "id": "A0A8V0YHN9", "url": "https://omabrowser.org/oma/group/A0A8V0YHN9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1RXV0-1", "protein_name": "Asparagine synthetase domain-containing protein 1", "gene_name": "ASNSD1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MCGICCAVSFSIEHFSKNLKEDLLCNLKRRGPNSSKQLLKSNADYHCLFSGHVLHLRGVLTAQPVEDERGNVFLWNGEVFGGIKVAPEENDTQIMFNYLSSCKNESDILSVFSEVQGPWSFIYYQASSHSLWFGRDFFGRRSLLWQFSNLGKSFCLSSVATQTSGVVNQWQEVPASGIFRIDLLSASISKSVVLKLYPWKYNAGNNVIKECAGSLTLISADLPTFVSVVENEAKLYLKEPVVPLNMMLPQAPFEIHCSGISSIPPRETLKVFLTDGHMNEVVQQFIDVLSAAVKRRVLCLPRDENLSPSEVLKTNNRKANVAILFSGGVDSMVIAALADRHIPLDEPIDLLNVAFIMKEKSTPTHFNKEGKKQKNHYEIPPEESSKNALAAASASPDEQFNVPDRITGRTGLRELQAANPSRVWNFVEINVSLEELQKFRRTRISHLVQPLDTVLDDSIGCAVWFASGGVGWLVTQDEAKHYQSRAKVVLTGIGADEQLGGYSRHRVRFQKHGLEGLNKEIEMELGRISSRNLGRDDRVIGDHGKEARFPFLDENVVSFLNSLPVWEKANLTLPRGIGEKLILRLAAMELGLTTSALLPKRAMQFGSRIAKMEKNNEKASDKCGRLQVISLENLSIEEEIQL", "length": 642 }, "evidence": [ { "id": "A0A8V0YHN9", "url": "https://omabrowser.org/oma/group/A0A8V0YHN9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3IMR5-1", "protein_name": "Asparagine synthetase domain-containing protein 1", "gene_name": "Asnsd1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MCGICCSVGFSDEHFSKELKEDLLCNLRRRGPNNSKQLLKSGVNYQCLFSGHVLHLRGVLTAQPVEDESGNVFLWNGEVFDGVQVEAEDSDTQVMFSSLSACKNESDILSLFSRVQGPWSFIYYQASSHYLWFGRDFFGRRSLLWRFNNLGNSFFLSSVGDQISGLADKWQEVPASGIFQIDLNSSAVSRHVSIKLYPWKYVSKENFIEKCSNDLPHTAAELPAFVSVVANEDKLYLSKPVVPLNKMLPQAPLETHCRNSSGVPHSRETLAMFLTDEHTKKVVHQFIDVLSVAVKRRVLCLVRKENPVSKEVLKTWNKTANIAILFSGGVDSMVIAALADRHIPLDEPIDLLNVAFVTKRKTGPSVTKVERKRQTHHEIPSEESSWGATVAQGLDDVEVPDRVTGKAGLKELQSINPSRTWNFVEINVSLEELQKLRRARICHLVQPLDTVLDDSIGCAVWFASRGVGWLVTQDAVRSYKSSAKVILTGIGADEQLAGYSRHRVRFQSLGLEGLNEEIAMELGRISSRNLSRDDRVIGDHGKEARFPFLDENVVSFLNSLPVWEKVDLSLPRGVGEKLILRLAAVELGLTASALLPKRAMQFGSRIAKLEKTDEKASDKCGRLQILP", "length": 627 }, "evidence": [ { "id": "A0A8V0YHN9", "url": "https://omabrowser.org/oma/group/A0A8V0YHN9/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q54YK5-1", "protein_name": "Glutamine amidotransferase type-2 domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MCGISVIINGIKILEPINKNGQNKDLKETITTSTSTPTPIAIGDYYTIKNDIESRLINRGPDSIKSKLIEIKCFQKDIDKEISISMELISSVLGLRGPLTIQPLTDENNGNTLLWNGELFGGYEIGIHDNDTCLLLHLLSKINENESENQEINENEIERELIEIMLKIKGPFAFLYWQEKKRKLWFGRDVLGRRSLLVNNETIINDKPSLIISSMGSFPNGIDDSIRLPKWDEINTFGLFSIHFPKIIETNIIHFKIHPWDISNINLNIGMISLDYDNDNDNEEESNTNTTTTTTTTTTKEIEEIEGNNIDQLHFYPFGRREKLDIEKGEWSEKVFNDYVNGFYEAISDSINVRLNNLPIASLEIPDLIRAPFLQEKPLPLVSRLGILFSGGLDSMVLAAMSNKHMETPDEPIHLINVAFGDDDSPFEEYDKVPDRKAAISGLKELQTIAPNRQWKLIKVNVGTKEMEWAKKIVYQLSYPAITIMDMTICLALWFAGRGEGILHGEELKGQGQQQQQRYMTTFVYPRFPYLDESLISYLNGIELPYICDLSLPQGTGDKRILREVGPIQFGSRSSKQLNKNVPARITQKCGKDVFSFTTPIYDPLQDPGYEALQKQKLKQKMSLERKEKKNKEKSEKIEKKINFKNQQEKQKQQPNDDENILRKKEVKNCN", "length": 671 }, "evidence": [ { "id": "A0A8V0YHN9", "url": "https://omabrowser.org/oma/group/A0A8V0YHN9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q8BFS9-1", "protein_name": "Asparagine synthetase domain-containing protein 1", "gene_name": "Asnsd1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MCGICCSVSFSIEHFSKELKEDLLHNLRRRGPNSSRQLLKSAVNYQCLFSGHVLHLRGVLTIQPVEDEHGNVFLWNGEVFNGVKVEAEDNDTQVMFNSLSACKNESEILLLFSKVQGPWSFIYYQASSHHLWFGRDFFGRRSLLWQFSNLGKSFCLSSVGTQVYGVADQWQEVPASGIFQIDLNSAAVSRSVILKLYPWRYISKEDIAEECGNDLTQTPAGLPEFVSVVINEANLYLSKPVVPLNKKLPESPLEIQCRNSSSTSGTRETLEVFLTDEHTKKIVQQFIAILNVSVKRRILCLAREENLASKEVLKTCSSKANIAILFSGGVDSMVIAALADRHIPLDEPIDLLNVAFVPKQKTGLPIPNIERKQQNHHEIPSEESSQSPAADEGPGEAEVPDRVTGKAGLKELQSVNPSRTWNFVEINVSLEELQKLRRARICHLVQPLDTVLDDSIGCAVWFASRGIGWLVTQDAVRSYKSSAKVILTGIGADEQLAGYSRHRARFQSLGLEGLNEEIAMELGRISSRNLGRDDRVIGDHGKEARFPFLDENVVSFLNSLPVWEKVDLTLPRGVGEKLILRLAAMELGLPASALLPKRAIQFGSRIAKLEKSNEKASDKCGRLQILP", "length": 627 }, "evidence": [ { "id": "A0A8V0YHN9", "url": "https://omabrowser.org/oma/group/A0A8V0YHN9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9NWL6-1", "protein_name": "Asparagine synthetase domain-containing protein 1", "gene_name": "ASNSD1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MCGICCSVNFSAEHFSQDLKEDLLYNLKQRGPNSSKQLLKSDVNYQCLFSAHVLHLRGVLTTQPVEDERGNVFLWNGEIFSGIKVEAEENDTQILFNYLSSCKNESEILSLFSEVQGPWSFIYYQASSHYLWFGRDFFGRRSLLWHFSNLGKSFCLSSVGTQTSGLANQWQEVPASGLFRIDLKSTVISGCIILQLYPWKYISRENIIEENVNSLSQISADLPAFVSVVANEAKLYLEKPVVPLNMMLPQAALETHCSNISNVPPTREILQVFLTDVHMKEVIQQFIDVLSVAVKKRVLCLPRDENLTANEVLKTCDRKANVAILFSGGIDSMVIATLADRHIPLDEPIDLLNVAFIAEEKTMPTTFNREGNKQKNKCEIPSEEFSKDVAAAAADSPNKHVSVPDRITGRAGLKELQAVSPSRIWNFVEINVSMEELQKLRRTRICHLIRPLDTVLDDSIGCAVWFASRGIGWLVAQEGVKSYQSNAKVVLTGIGADEQLAGYSRHRVRFQSHGLEGLNKEIMMELGRISSRNLGRDDRVIGDHGKEARFPFLDENVVSFLNSLPIWEKANLTLPRGIGEKLLLRLAAVELGLTASALLPKRAMQFGSRIAKMEKINEKASDKCGRLQIMSLENLSIEKETKL", "length": 643 }, "evidence": [ { "id": "A0A8V0YHN9", "url": "https://omabrowser.org/oma/group/A0A8V0YHN9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "L-asparagine biosynthetic process", "id": "GO:0070981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070981", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHN9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHN9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 152, "end_pos": 154, "annotation": "n_glycosylation_sequon" }, { "start_pos": 235, "end_pos": 237, "annotation": "n_glycosylation_sequon" }, { "start_pos": 249, "end_pos": 251, "annotation": "n_glycosylation_sequon" }, { "start_pos": 437, "end_pos": 439, "annotation": "n_glycosylation_sequon" }, { "start_pos": 93, "end_pos": 95, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YHN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHN9" }, { "id": "PS51278", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51278" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Glutamine amidotransferase type-2", "eco_id": "ECO_0000259", "start_pos": 2, "end_pos": 187, "start_aa": "Cys", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 152, "end_pos": 154 }, { "start_pos": 235, "end_pos": 237 }, { "start_pos": 249, "end_pos": 251 }, { "start_pos": 437, "end_pos": 439 }, { "start_pos": 93, "end_pos": 95 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YHR1-1", "uniprot_ac": "A0A8V0YHR1", "uniprot_id": "A0A8V0YHR1_CHICK", "mass": { "chemical_mass": 300635.0, "monoisotopic_mass": 300635.0 }, "refseq": {}, "gene_names": [ { "name": "FBN2", "type": "recommended", "evidence": [ { "id": "A0A8V0YHR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHR1" } ] } ], "protein_names": [ { "name": "Fibrillin-2", "type": "recommended", "evidence": [ { "id": "A0A8V0YHR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHR1/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Fibrillins are structural components of 10-12 nm extracellular calcium-binding microfibrils, which occur either in association with elastin or in elastin-free bundles. Fibrillin-2-containing microfibrils regulate the early process of elastic fiber assembly. Regulates osteoblast maturation by controlling TGF-beta bioavailability and calibrating TGF-beta and BMP levels, respectively.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHR1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHR1#function" }, { "database": "UniProtKB", "id": "ARBA00054421", "url": "https://www.uniprot.org/uniprotkb/ARBA00054421#function" }, { "database": "UniProtKB", "id": "A0A8V0YBD0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBD0#function" }, { "database": "UniProtKB", "id": "A0A8V0YHP9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHP9#function" } ] }, { "annotation": "Hormone secreted by trophoblasts that promotes trophoblast invasiveness. Has glucogenic activity: is able to increase plasma glucose levels.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHR1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHR1#function" }, { "database": "UniProtKB", "id": "ARBA00053574", "url": "https://www.uniprot.org/uniprotkb/ARBA00053574#function" }, { "database": "UniProtKB", "id": "A0A8V0YBD0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBD0#function" }, { "database": "UniProtKB", "id": "A0A8V0YHP9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHP9#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHR1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHR1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "FBN2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHR1", "locus": { "chromosome": "Z", "start_pos": 57572115, "end_pos": 57735283, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012940", "url": "https://www.ensembl.org/id/ENSGALG00010012940" } ] } } ], "crossref": [ { "id": "cd00054", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00054", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000152", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000152", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000742", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000742", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001881", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001881", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009030", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009030", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013032", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013032", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017878", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017878", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018097", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018097", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024731", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024731", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR026823", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026823", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036773", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036773", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR049883", "url": "https://www.ebi.ac.uk/interpro/entry/IPR049883", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052080", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052080", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YBD0", "url": "https://www.orthodb.org/?gene=A0A8V0YBD0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YHP9", "url": "https://www.orthodb.org/?gene=A0A8V0YHP9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YHR1", "url": "https://www.orthodb.org/?gene=A0A8V0YHR1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47333", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47333", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47333:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47333:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00683", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00683", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07645", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07645", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12661", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12661", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12662", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12662", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12947", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12947", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14670", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14670", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-1474228", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1474228", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-1566948", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1566948", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-2129379", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2129379", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YBD0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBD0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YBD0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBD0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHP9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHP9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHP9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHP9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHR1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHR1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHR1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHR1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MCTCASGQISPTCGPKSTQQCSIRCMNGGTCADDRCQCQKGYIGVYCGQPVCEKGCQNGGRCIGPNRCACVYGFTGPQCERDYRTGPCFTQVNNQMCQGQLTGIVCTKTLCCATIGRAWGHPCEMCPAQPQPCRRGFIPNIRTGACQDVDECQAIPGVCQGGNCINTVGSYECKCPAGHRQNEATQKCDDIDECIIIPGVCEGGECSNTVGSYFCLCPRGYVSSTDGSRCIDQRASTCFSNLVNGRCAQELPGRFTKRQCCCESGRCWAIGSVPEMCPVRGSDEHRRLCVDGVPAGGGSRSGGGTGGNGFLPGGNGNGYSPGGAGFIPVPGSNGFSPGVGGAGVGTGGQTPAGNGPIITGLTILNQTIDICKHHPNLCLNGRCIPTISSYRCECNMGYKQDANGDCIDVDECTSNPCSNGDCVNTPGSYYCKCHAGFQRTPTKQACIDIDECIQNGVLCKNGRCVNTDGSFQCICNAGFELTTDGKNCVDHDECTTTNMCLNGMCINEDGSFKCICKPGFVLAPNGRYCTDIDECQTSGICMNGHCINTEGSFRCECPPGLAVGVDGRVCVDTHMRSTCYGGIKKGACIRPFPGAVTKSECCCANPDYGFGEPCQPCPAKNSAEFHGLCSSGIGITVDGRDINECALDPDICSNGICENLRGSYRCNCNSGYEPEPSGRNCVDIDECSVNGLLCDNGLCRNTPGSYSCTCPKGYVFSTETDTCEDTNECESSPCVNGACRNNLGSFSCECSPGSKLDSTGLICIDSLKGTCWLNIQDSRCEVNINGATLKSECCATLGAAWGSPCERCELDTACSRGFARVKGVTCEDVNECDVFPGVCPNGRCVNSRGSFHCECPEGLTLDGTGRVCLDIRMEQCYLKWDEDECIQSVPGKFRMDACCCAVGAAWGSDCEECPKPGTKEYEALCPRGPGFSNRGDILTGRPFYKDINECKVFPGMCMNGKCRNTIGSFKCRCNSGFALDMEERNCTDIDECRISPDLCGSGTCVNTPGSFECECFDGYESGFMMMKNCMDIDECERNPLLCRGGMCVNTEGSFQCDCPVGHELSPSREECIDVNECSLSDNLCRNGNCVNMVGTYQCSCNSGYQATADRQGCVDIDECMIMNGGCDTHCTNSEGSYECSCSDGYALMPDVRTCADIDECENNPDICDGGQCSNIPGEYRCLCYDGFMASMDMKTCIDVNECDLNSNICMFGECENTKGSFICHCQLGYSVKKGTTGCTDVDECEIGAHNCDMHASCVNVPGSFKCTCREGWFGNGIKCIDLDECSNGTHQCSVNAQCVNTPGSYRCACAEGFTGDGFTCSDVDECAENINLCENGQCLNVPGAYRCECEMGFTPASDSKSCQDIDECSFQNICVFGTCNNLPGMFHCICDDGYELDRSGGNCTDIDECADPINCVNGLCVNTPGRYECNCPPDFQLNPTGVGCVDNRVGNCYLKYGPRGDGSLSCNTEIGVGVSRSSCCCSLGKAWGNPCETCPPVNSTEYNTLCPGGEGFRPNPITIILEDIDECQELPGLCQGGNCINTFGSFQCECPKGYYLSEETRICEDIDECVAHPGVCGPGTCYNTLGNYTCICPPEYMQVNGGHNCMDMRKSFCYRSYNGTTCENELPFNVTKRMCCCTYNVGKAWNKPCEPCPTPGTAEFKNICGNIPGFTFDIHTGKAVDIDECKEIPGICANGVCINQIGSFRCECPTGFSYNDLLLVCEDIDECSNGDNLCQRNADCINSPGSYRCECAAGFKLSPNGACVDRNECLEIPNVCSHGLCVDMQGSYQCICHNGFKASQDQTMCMDVDECERHPCGNGTCKNTVGSYNCLCYPGFELTHNNDCMDIDECSSFFGQVCRNGRCFNEIGSFKCLCNEGYELTLDGKNCIDTNECVALPGSCSPGTCQNLEGSFRCICPPGYEVKSESCIDINECNEDPNICLFGSCTNTPGGFQCICPTGFVLSDNGRRCFDTRQSFCFTNFENGKCSVPKAFNTTKAKCCCSKMPGEGWGDPCELCPKEEEVAFQDLCPYGHGTIPGIDDTREDVNECLESPGICSNGHCINTDGSFRCECPMGYNLDFTGVHCIDTDECSIGNPCGNGTCTNVIGSFECNCHEGFEPGPMMNCEDINECAQNPLLCAFRCINTYGFYECTCPVGYELRDDQKMCKDLDECAEGLHDCESRGMMCKNLIGTFMCICPPGMTRRPDGEGCTDENECRTKPGICENGRCMNVIGSYRCECNEGFLSSPSGIECLDNRQGFCFAEVLQTMCQMASSSRNLVTKSECCCDGGRGWGNQCELCPLPGTTQYKKLCPHGPGYTTDGRDIDECKVMPNLCRHGQCINTMGSFRCFCKVGYTTDISSTSCVDLDECSQSPKPCNFICKNSEGSYQCSCPRGYILQEDGKTCKDLDECQTKQHNCQFLCVNTLGGFTCKCPPGFTQHHTACIDNNECGSQPSLCGSKGICQNTPGSFTCECQRGFSLDSTGLNCEDVDECDGNHRCQHGCQNILGGYRCGCPQGYIQHYQWNQCVDENECSNPNTCGSASCYNTLGSYKCACPSGFSYDQFSSACHDVNECSSAKNPCNYGCSNTEGGYLCGCPPGYYRVGQGHCVSGMGFNKGQYVPVDEDADEENALSPEACYECKINGYPKKDNRRKRSLNETIEQVSLESLDMDSPLKMRVNISRLDNKEHILELMPAIEPLTNHVRYIISHGNDDGVFRIHQRDGLSYLHTAKKKSVPGTYTLEITSIPLYKKKELKKLEDSNEDSYLLGELGEALRMRLWLELY", "length": 2781, "header": "tr|A0A8V0YHR1-1|A0A8V0YHR1_CHICK Isoform 1 of Fibrillin-2 OS=Gallus gallus OX=9031 GN=FBN2 PE=3 SV=1 CANONICAL=A0A8V0YHR1-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YBD0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHR1/entry#A0A8V0YBD0-1", "sequence": { "sequence": "MCTCASGQISPTCGPKSTQQCSIRCMNGGTCADDRCQCQKGYIGVYCGQPVCEKGCQNGGRCIGPNRCACVYGFTGPQCERDYRTGPCFTQVNNQMCQGQLTGIVCTKTLCCATIGRAWGHPCEMCPAQPQPCRRGFIPNIRTGACQDVDECQAIPGVCQGGNCINTVGSYECKCPAGHRQNEATQKCDDQRASTCFSNLVNGRCAQELPGRFTKRQCCCESGRCWAIGSVPEMCPVRGSDEHRRLCVDGVPAGGGSRSGGGTGGNGFLPGGNGNGYSPGGAGFIPVPGSNGFSPGVGGAGVGTGGQTPAGNGPIITGLTILNQTIDICKHHPNLCLNGRCIPTISSYRCECNMGYKQDANGDCIDVDECTSNPCSNGDCVNTPGSYYCKCHAGFQRTPTKQACIDIDECIQNGVLCKNGRCVNTDGSFQCICNAGFELTTDGKNCVDHDECTTTNMCLNGMCINEDGSFKCICKPGFVLAPNGRYCTDIDECQTSGICMNGHCINTEGSFRCECPPGLAVGVDGRVCVDTHMRSTCYGGIKKGACIRPFPGAVTKSECCCANPDYGFGEPCQPCPAKNSAEFHGLCSSGIGITVDGRDINECALDPDICSNGICENLRGSYRCNCNSGYEPEPSGRNCVDIDECSVNGLLCDNGLCRNTPGSYSCTCPKGYVFSTETDTCEDTNECESSPCVNGACRNNLGSFSCECSPGSKLDSTGLICIDSLKGTCWLNIQDSRCEVNINGATLKSECCATLGAAWGSPCERCELDTACSRGFARVKGVTCEDVNECDVFPGVCPNGRCVNSRGSFHCECPEGLTLDGTGRVCLDIRMEQCYLKWDEDECIQSVPGKFRMDACCCAVGAAWGSDCEECPKPGTKEYEALCPRGPGFSNRGDILTGRPFYKDINECKVFPGMCMNGKCRNTIGSFKCRCNSGFALDMEERNCTDIDECRISPDLCGSGTCVNTPGSFECECFDGYESGFMMMKNCMDIDECERNPLLCRGGMCVNTEGSFQCDCPVGHELSPSREECIDVNECSLSDNLCRNGNCVNMVGTYQCSCNSGYQATADRQGCVDIDECMIMNGGCDTHCTNSEGSYECSCSDGYALMPDVRTCADIDECENNPDICDGGQCSNIPGEYRCLCYDGFMASMDMKTCIDVNECDLNSNICMFGECENTKGSFICHCQLGYSVKKGTTGCTDVDECEIGAHNCDMHASCVNVPGSFKCTCREGWFGNGIKCIDLDECSNGTHQCSVNAQCVNTPGSYRCACAEGFTGDGFTCSDVDECAENINLCENGQCLNVPGAYRCECEMGFTPASDSKSCQDIDECSFQNICVFGTCNNLPGMFHCICDDGYELDRSGGNCTDIDECADPINCVNGLCVNTPGRYECNCPPDFQLNPTGVGCVDNRVGNCYLKYGPRGDGSLSCNTEIGVGVSRSSCCCSLGKAWGNPCETCPPVNSTEYNTLCPGGEGFRPNPITIILEDIDECQELPGLCQGGNCINTFGSFQCECPKGYYLSEETRICEDIDECVAHPGVCGPGTCYNTLGNYTCICPPEYMQVNGGHNCMDMRKSFCYRSYNGTTCENELPFNVTKRMCCCTYNVGKAWNKPCEPCPTPGTAEFKNICGNIPGFTFDIHTGKAVDIDECKEIPGICANGVCINQIGSFRCECPTGFSYNDLLLVCEDIDECSNGDNLCQRNADCINSPGSYRCECAAGFKLSPNGACVDRNECLEIPNVCSHGLCVDMQGSYQCICHNGFKASQDQTMCMDVDECERHPCGNGTCKNTVGSYNCLCYPGFELTHNNDCMDIDECSSFFGQVCRNGRCFNEIGSFKCLCNEGYELTLDGKNCIDTNECVALPGSCSPGTCQNLEGSFRCICPPGYEVKSESCIDINECNEDPNICLFGSCTNTPGGFQCICPTGFVLSDNGRRCFDTRQSFCFTNFENGKCSVPKAFNTTKAKCCCSKMPGEGWGDPCELCPKEEEVAFQDLCPYGHGTIPGIDDTREDVNECLESPGICSNGHCINTDGSFRCECPMGYNLDFTGVHCIDTDECSIGNPCGNGTCTNVIGSFECNCHEGFEPGPMMNCEDINECAQNPLLCAFRCINTYGFYECTCPVGYELRDDQKMCKDLDECAEGLHDCESRGMMCKNLIGTFMCICPPGMTRRPDGEGCTDENECRTKPGICENGRCMNVIGSYRCECNEGFLSSPSGIECLDNRQGFCFAEVLQTMCQMASSSRNLVTKSECCCDGGRGWGNQCELCPLPGTTQYKKLCPHGPGYTTDGRDIDECKVMPNLCRHGQCINTMGSFRCFCKVGYTTDISSTSCVDLDECSQSPKPCNFICKNSEGSYQCSCPRGYILQEDGKTCKDLDECQTKQHNCQFLCVNTLGGFTCKCPPGFTQHHTACIDNNECGSQPSLCGSKGICQNTPGSFTCECQRGFSLDSTGLNCEDVDECDGNHRCQHGCQNILGGYRCGCPQGYIQHYQWNQCVDENECSNPNTCGSASCYNTLGSYKCACPSGFSYDQFSSACHDVNECSSAKNPCNYGCSNTEGGYLCGCPPGYYRVGQGHCVSGMGFNKGQYVPVDEDADEENALSPEACYECKINGYPKKDNRRKRSLNETIEQVSLESLDMDSPLKMRVNISRLDNKEHILELMPAIEPLTNHVRYIISHGNDDGVFRIHQRDGLSYLHTAKKKSVPGTYTLEITSIPLYKKKELKKLEDSNEDSYLLGELGEALRMRLWLELY", "length": 2739, "header": "tr|A0A8V0YBD0-1|A0A8V0YBD0_CHICK Computationally mapped isoform of Fibrillin-2 OS=Gallus gallus OX=9031 GN=FBN2 PE=3 SV=1 CANONICAL=A0A8V0YHR1-1" }, "locus": { "chromosome": "Z", "start_pos": 57731380, "end_pos": 57573599, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031084.1", "url": "https://www.ensembl.org/id/ENSGALT00010031084.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018078.1", "url": "https://www.ensembl.org/id/ENSGALP00010018078.1" } ] } }, { "isoform_ac": "A0A8V0YHP9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHR1/entry#A0A8V0YHP9-1", "sequence": { "sequence": "MCTCASGQISPTCGPKSTQQCSIRCMNGGTCADDRCQCQKGYIGVYCGQPVCEKGCQNGGRCIGPNRCACVYGFTGPQCERDYRTGPCFTQVNNQMCQGQLTGIVCTKTLCCATIGRAWGHPCEMCPAQPQPCRRGFIPNIRTGACQDIDECIIIPGVCEGGECSNTVGSYFCLCPRGYVSSTDGSRCIDQRASTCFSNLVNGRCAQELPGRFTKRQCCCESGRCWAIGSVPEMCPVRGSDEHRRLCVDGVPAGGGSRSGGGTGGNGFLPGGNGNGYSPGGAGFIPVPGSNGFSPGVGGAGVGTGGQTPAGNGPIITGLTILNQTIDICKHHPNLCLNGRCIPTISSYRCECNMGYKQDANGDCIDVDECTSNPCSNGDCVNTPGSYYCKCHAGFQRTPTKQACIDIDECIQNGVLCKNGRCVNTDGSFQCICNAGFELTTDGKNCVDHDECTTTNMCLNGMCINEDGSFKCICKPGFVLAPNGRYCTDIDECQTSGICMNGHCINTEGSFRCECPPGLAVGVDGRVCVDTHMRSTCYGGIKKGACIRPFPGAVTKSECCCANPDYGFGEPCQPCPAKNSAEFHGLCSSGIGITVDGRDINECALDPDICSNGICENLRGSYRCNCNSGYEPEPSGRNCVDIDECSVNGLLCDNGLCRNTPGSYSCTCPKGYVFSTETDTCEDTNECESSPCVNGACRNNLGSFSCECSPGSKLDSTGLICIDSLKGTCWLNIQDSRCEVNINGATLKSECCATLGAAWGSPCERCELDTACSRGFARVKGVTCEDVNECDVFPGVCPNGRCVNSRGSFHCECPEGLTLDGTGRVCLDIRMEQCYLKWDEDECIQSVPGKFRMDACCCAVGAAWGSDCEECPKPGTKEYEALCPRGPGFSNRGDILTGRPFYKDINECKVFPGMCMNGKCRNTIGSFKCRCNSGFALDMEERNCTDIDECRISPDLCGSGTCVNTPGSFECECFDGYESGFMMMKNCMDIDECERNPLLCRGGMCVNTEGSFQCDCPVGHELSPSREECIDVNECSLSDNLCRNGNCVNMVGTYQCSCNSGYQATADRQGCVDIDECMIMNGGCDTHCTNSEGSYECSCSDGYALMPDVRTCADIDECENNPDICDGGQCSNIPGEYRCLCYDGFMASMDMKTCIDVNECDLNSNICMFGECENTKGSFICHCQLGYSVKKGTTGCTDVDECEIGAHNCDMHASCVNVPGSFKCTCREGWFGNGIKCIDLDECSNGTHQCSVNAQCVNTPGSYRCACAEGFTGDGFTCSDVDECAENINLCENGQCLNVPGAYRCECEMGFTPASDSKSCQDIDECSFQNICVFGTCNNLPGMFHCICDDGYELDRSGGNCTDIDECADPINCVNGLCVNTPGRYECNCPPDFQLNPTGVGCVDNRVGNCYLKYGPRGDGSLSCNTEIGVGVSRSSCCCSLGKAWGNPCETCPPVNSTEYNTLCPGGEGFRPNPITIILEDIDECQELPGLCQGGNCINTFGSFQCECPKGYYLSEETRICEDIDECVAHPGVCGPGTCYNTLGNYTCICPPEYMQVNGGHNCMDMRKSFCYRSYNGTTCENELPFNVTKRMCCCTYNVGKAWNKPCEPCPTPGTAEFKNICGNIPGFTFDIHTGKAVDIDECKEIPGICANGVCINQIGSFRCECPTGFSYNDLLLVCEDIDECSNGDNLCQRNADCINSPGSYRCECAAGFKLSPNGACVDRNECLEIPNVCSHGLCVDMQGSYQCICHNGFKASQDQTMCMDVDECERHPCGNGTCKNTVGSYNCLCYPGFELTHNNDCMDIDECSSFFGQVCRNGRCFNEIGSFKCLCNEGYELTLDGKNCIDTNECVALPGSCSPGTCQNLEGSFRCICPPGYEVKSESCIDINECNEDPNICLFGSCTNTPGGFQCICPTGFVLSDNGRRCFDTRQSFCFTNFENGKCSVPKAFNTTKAKCCCSKMPGEGWGDPCELCPKEEEVAFQDLCPYGHGTIPGIDDTREDVNECLESPGICSNGHCINTDGSFRCECPMGYNLDFTGVHCIDTDECSIGNPCGNGTCTNVIGSFECNCHEGFEPGPMMNCEDINECAQNPLLCAFRCINTYGFYECTCPVGYELRDDQKMCKDLDECAEGLHDCESRGMMCKNLIGTFMCICPPGMTRRPDGEGCTDENECRTKPGICENGRCMNVIGSYRCECNEGFLSSPSGIECLDNRQGFCFAEVLQTMCQMASSSRNLVTKSECCCDGGRGWGNQCELCPLPGTTQYKKLCPHGPGYTTDGRDIDECKVMPNLCRHGQCINTMGSFRCFCKVGYTTDISSTSCVDLDECSQSPKPCNFICKNSEGSYQCSCPRGYILQEDGKTCKDLDECQTKQHNCQFLCVNTLGGFTCKCPPGFTQHHTACIDNNECGSQPSLCGSKGICQNTPGSFTCECQRGFSLDSTGLNCEDVDECDGNHRCQHGCQNILGGYRCGCPQGYIQHYQWNQCVDENECSNPNTCGSASCYNTLGSYKCACPSGFSYDQFSSACHDVNECSSAKNPCNYGCSNTEGGYLCGCPPGYYRVGQGHCVSGMGFNKGQYVPVDEDADEENALSPEACYECKINGYPKKDNRRKRSLNETIEQVSLESLDMDSPLKMRVNISRLDNKEHILELMPAIEPLTNHVRYIISHGNDDGVFRIHQRDGLSYLHTAKKKSVPGTYTLEITSIPLYKKKELKKLEDSNEDSYLLGELGEALRMRLWLELY", "length": 2739, "header": "tr|A0A8V0YHP9-1|A0A8V0YHR1_CHICK Computationally mapped isoform of Fibrillin-2 OS=Gallus gallus OX=9031 GN=FBN2 PE=3 SV=1 CANONICAL=A0A8V0YHR1-1" }, "locus": { "chromosome": "Z", "start_pos": 57731380, "end_pos": 57573599, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031069.1", "url": "https://www.ensembl.org/id/ENSGALT00010031069.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018064.1", "url": "https://www.ensembl.org/id/ENSGALP00010018064.1" } ] } }, { "isoform_ac": "A0A8V0YHR1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHR1/entry#A0A8V0YHR1-1", "sequence": { "sequence": "MCTCASGQISPTCGPKSTQQCSIRCMNGGTCADDRCQCQKGYIGVYCGQPVCEKGCQNGGRCIGPNRCACVYGFTGPQCERDYRTGPCFTQVNNQMCQGQLTGIVCTKTLCCATIGRAWGHPCEMCPAQPQPCRRGFIPNIRTGACQDVDECQAIPGVCQGGNCINTVGSYECKCPAGHRQNEATQKCDDIDECIIIPGVCEGGECSNTVGSYFCLCPRGYVSSTDGSRCIDQRASTCFSNLVNGRCAQELPGRFTKRQCCCESGRCWAIGSVPEMCPVRGSDEHRRLCVDGVPAGGGSRSGGGTGGNGFLPGGNGNGYSPGGAGFIPVPGSNGFSPGVGGAGVGTGGQTPAGNGPIITGLTILNQTIDICKHHPNLCLNGRCIPTISSYRCECNMGYKQDANGDCIDVDECTSNPCSNGDCVNTPGSYYCKCHAGFQRTPTKQACIDIDECIQNGVLCKNGRCVNTDGSFQCICNAGFELTTDGKNCVDHDECTTTNMCLNGMCINEDGSFKCICKPGFVLAPNGRYCTDIDECQTSGICMNGHCINTEGSFRCECPPGLAVGVDGRVCVDTHMRSTCYGGIKKGACIRPFPGAVTKSECCCANPDYGFGEPCQPCPAKNSAEFHGLCSSGIGITVDGRDINECALDPDICSNGICENLRGSYRCNCNSGYEPEPSGRNCVDIDECSVNGLLCDNGLCRNTPGSYSCTCPKGYVFSTETDTCEDTNECESSPCVNGACRNNLGSFSCECSPGSKLDSTGLICIDSLKGTCWLNIQDSRCEVNINGATLKSECCATLGAAWGSPCERCELDTACSRGFARVKGVTCEDVNECDVFPGVCPNGRCVNSRGSFHCECPEGLTLDGTGRVCLDIRMEQCYLKWDEDECIQSVPGKFRMDACCCAVGAAWGSDCEECPKPGTKEYEALCPRGPGFSNRGDILTGRPFYKDINECKVFPGMCMNGKCRNTIGSFKCRCNSGFALDMEERNCTDIDECRISPDLCGSGTCVNTPGSFECECFDGYESGFMMMKNCMDIDECERNPLLCRGGMCVNTEGSFQCDCPVGHELSPSREECIDVNECSLSDNLCRNGNCVNMVGTYQCSCNSGYQATADRQGCVDIDECMIMNGGCDTHCTNSEGSYECSCSDGYALMPDVRTCADIDECENNPDICDGGQCSNIPGEYRCLCYDGFMASMDMKTCIDVNECDLNSNICMFGECENTKGSFICHCQLGYSVKKGTTGCTDVDECEIGAHNCDMHASCVNVPGSFKCTCREGWFGNGIKCIDLDECSNGTHQCSVNAQCVNTPGSYRCACAEGFTGDGFTCSDVDECAENINLCENGQCLNVPGAYRCECEMGFTPASDSKSCQDIDECSFQNICVFGTCNNLPGMFHCICDDGYELDRSGGNCTDIDECADPINCVNGLCVNTPGRYECNCPPDFQLNPTGVGCVDNRVGNCYLKYGPRGDGSLSCNTEIGVGVSRSSCCCSLGKAWGNPCETCPPVNSTEYNTLCPGGEGFRPNPITIILEDIDECQELPGLCQGGNCINTFGSFQCECPKGYYLSEETRICEDIDECVAHPGVCGPGTCYNTLGNYTCICPPEYMQVNGGHNCMDMRKSFCYRSYNGTTCENELPFNVTKRMCCCTYNVGKAWNKPCEPCPTPGTAEFKNICGNIPGFTFDIHTGKAVDIDECKEIPGICANGVCINQIGSFRCECPTGFSYNDLLLVCEDIDECSNGDNLCQRNADCINSPGSYRCECAAGFKLSPNGACVDRNECLEIPNVCSHGLCVDMQGSYQCICHNGFKASQDQTMCMDVDECERHPCGNGTCKNTVGSYNCLCYPGFELTHNNDCMDIDECSSFFGQVCRNGRCFNEIGSFKCLCNEGYELTLDGKNCIDTNECVALPGSCSPGTCQNLEGSFRCICPPGYEVKSESCIDINECNEDPNICLFGSCTNTPGGFQCICPTGFVLSDNGRRCFDTRQSFCFTNFENGKCSVPKAFNTTKAKCCCSKMPGEGWGDPCELCPKEEEVAFQDLCPYGHGTIPGIDDTREDVNECLESPGICSNGHCINTDGSFRCECPMGYNLDFTGVHCIDTDECSIGNPCGNGTCTNVIGSFECNCHEGFEPGPMMNCEDINECAQNPLLCAFRCINTYGFYECTCPVGYELRDDQKMCKDLDECAEGLHDCESRGMMCKNLIGTFMCICPPGMTRRPDGEGCTDENECRTKPGICENGRCMNVIGSYRCECNEGFLSSPSGIECLDNRQGFCFAEVLQTMCQMASSSRNLVTKSECCCDGGRGWGNQCELCPLPGTTQYKKLCPHGPGYTTDGRDIDECKVMPNLCRHGQCINTMGSFRCFCKVGYTTDISSTSCVDLDECSQSPKPCNFICKNSEGSYQCSCPRGYILQEDGKTCKDLDECQTKQHNCQFLCVNTLGGFTCKCPPGFTQHHTACIDNNECGSQPSLCGSKGICQNTPGSFTCECQRGFSLDSTGLNCEDVDECDGNHRCQHGCQNILGGYRCGCPQGYIQHYQWNQCVDENECSNPNTCGSASCYNTLGSYKCACPSGFSYDQFSSACHDVNECSSAKNPCNYGCSNTEGGYLCGCPPGYYRVGQGHCVSGMGFNKGQYVPVDEDADEENALSPEACYECKINGYPKKDNRRKRSLNETIEQVSLESLDMDSPLKMRVNISRLDNKEHILELMPAIEPLTNHVRYIISHGNDDGVFRIHQRDGLSYLHTAKKKSVPGTYTLEITSIPLYKKKELKKLEDSNEDSYLLGELGEALRMRLWLELY", "length": 2781, "header": "tr|A0A8V0YHR1-1|A0A8V0YHR1_CHICK Isoform 1 of Fibrillin-2 OS=Gallus gallus OX=9031 GN=FBN2 PE=3 SV=1 CANONICAL=A0A8V0YHR1-1" }, "locus": { "chromosome": "Z", "start_pos": 57731380, "end_pos": 57573599, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031081.1", "url": "https://www.ensembl.org/id/ENSGALT00010031081.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018074.1", "url": "https://www.ensembl.org/id/ENSGALP00010018074.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 12, "start_aa": "Thr", "end_pos": 12, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr12", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", 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"categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-426496", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-426496", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YC84", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC84", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YC84-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC84-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YC94", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC94", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YC94-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC94-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHR3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHR3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHR3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHR3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YIM3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIM3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YIM3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIM3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YIM8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIM8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YIM8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIM8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YKM5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKM5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YKM5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKM5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQTDEGEILEEGSPKMEHEDFVMEGHGKTPPPGEENKQEKEQEREEQLMEDKKRKKEDKKKKESAQKVTDQKTKVPEVTKPSLSQPVAASPIGNSPSPPVNGGNNAKRVAVPNGQPPSAARYMPREVPPRFRCQQDHKVLLKRGQPPPPSCMLLGGGAGPPPPTAPGANPNNAQPVTGALLQSDSGTATDSTIGGAAASNYANSTWGPGASSSSGTNANPTHIWDKVIVDGSDMEEWPCIASKDAESSSENTTDNNSASNPGLEKNTLPGSTTSNKGKGSQCQSGSAGNECNLGAWKSDPKAKSVQSSNPATESNSGLSNWRNLTGQDRIGSGSGFSNFNPNSNPSAWPALVQEGNSRKGTSESDSGSSNAQISTVGQTSREQQSKMENAGVNFVSGREQAQIHNTDGPKNGNTNSLNLSSPNPMENKGMPFEMGLGNPSRSTDTPSQSTGERKTGSVGSWGTARGSSGTDTVSGQSNSGNHGNNGKDREDSWKGASVQKPNGSRSDSWDNNNRSTGGGSWNFGPQHANESKWGEGNKLTSGVSQGEWKQLSGSDELKIGEWSGPNQPNSSTGAWDNQKGHPLPENQGNSQAPCWGRSSSSAGSEVGGQSTGSNHKAGSSDSHNSGRRSYRPTHPDCQAVLQTLLSRTDLDPRVLSNTGWGQTQIKQDTVWDIEEMPRSEGKSDKGTEGWESSATQTKNSGGWGDVPSQSNQIKSGWGELSTPTEWKDPKNTGGWNDYKNPNSSNWGGGRQEEKSSSSWNDSSSKDQGWGGRQPNQGWSSGKNGWGEEVDQAKNSNWESAGNKPASGWGEGGQNEIGTWGNGANTGSASKGGWDDCKRNSTWNETGRQPNSWNKQQQQQQQQQQETSGSWGPPPQTPSNGRPPNPNWNSGPQPAAPKDEEPSGWEEPSPQSISRKMDIDDGTSAWGDPSSYNYKNVNLWDKNSQGGQAPREQSLPTPMTSKSQASVWSKSTPPAPDNGTSAWGEPNETSPGWGEVDDTGASTTGWGNAPSNAPNAMKSSSKSMQDGWGESDGPVTGTRHSSWEEEEEGGVWNTAGSQGSSSSHNSTSWGQGGKKTQMKCSLKGGNSDSWMNPISKQFSNMGLLSQTEDIPGNKMDLSVGGLPDKKFEVDKRAMNLGDFNDIMRKDRSGFRPPNSKDMGTTDSGPYFEKLTLPFSNQDGCLGDEAPCSPFSPSPSYKLSPSGSTLSNVGLGAIGSGLSPQNYAARQGGNHGLFGNSTAQSRGMHTPVQPLNPSPNIRAQVPPQFLSPQVSASMLKQFPNSGLNPGLFNVGPQLSPQQIAMLSQLPQIPQFQLACQLLLQQQQQQQQLLQSQRKLSQAVRQQQEQQIARMVSALQQQQQRQPGMKHSPSHPVGPKPHIDSMVPNPLNVGLSDLQTKGQIPGYGSGFGSSSMDYGMVGGKEAGTESRFKQWTMMEGLPSVASQDANMHKNGAIVPPGKARGGSPYNQFDIIQGDPLGGHAGPAGDSWLPAKSPPTNKIGSKSSNASWPPEFQPGVPWKGIQNIDPESDPYVTPGSVLGGTATSPIVDTDHQLLRDNTTGSNSSLNTSLPSPGAWPYSASDNSFTNVHSTSAKFSDYKSTWSPDPIGHNPTHLSNKMWKNHISSRNTTGLPRPPPGLTNPKPSSPWNSTAPRSVRGWGAQDSRLASASTWSDGSSVRPSYWLVLHNLTPQIDGSTLRTICMQHGPLLTFHLNLTQGTALIRYNTKQEAAKAQTALHMCVLGNTTILAEFATDEEVSRFLTQAQPPTPAATPSAPTAGWQSLETGQNQTDPVGPALNLFGGSTGLGQWSSGGGGSSGGDLTGASLWGPPNYSSSLWGVPSVEDPHRMGSPAPLLPGDLLGGGSDSI", "length": 1861, "header": "tr|A0A8V0YHR3-1|A0A8V0YHR3_CHICK Isoform 1 of Trinucleotide repeat containing adaptor 6B OS=Gallus gallus OX=9031 GN= PE=1 SV=1 CANONICAL=A0A8V0YHR3-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YC84-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHR3/entry#A0A8V0YC84-1", "sequence": { "sequence": "MPREVPPRFRCQQDHKVLLKRGQPPPPSCMLLGGGAGPPPPTAPGANPNNAQPVTGALLQSDSGTATDSTIGGAAASNYANSTWGPGASSSSGTNANPTHIWDKVIVDGSDMEEWPCIASKDAESSSENTTDNNSASNPGLEKNTLPGSTTSNKGKGSQCQSGSAGNECNLGAWKSDPKAKSVQSSNPATESNSGLSNWRNLTGQDRIGSGSGFSNFNPNSNPSAWPALVQEGNSRKGTSESDSGSSNAQISTVGQTSREQQSKMENAGVNFVSGREQAQIHNTDGPKNGNTNSLNLSSPNPMENKGMPFEMGLGNPSRSTDTPSQSTGERKTGSVGSWGTARGSSGTDTVSGQSNSGNHGNNGKDREDSWKGASVQKPNGSRSDSWDNNNRSTGGGSWNFGPQHANESKWGEGNKLTSGVSQGEWKQLSGSDELKIGEWSGPNQPNSSTGAWDNQKGHPLPENQGNSQAPCWGRSSSSAGSEVGGQSTGSNHKAGSSDSHNSGRRSYRPTHPDCQAVLQTLLSRTDLDPRVLSNTGWGQTQIKQDTVWDIEEMPRSEGKSDKGTEGWESSATQTKNSGGWGDVPSQSNQIKSGWGELSTPTEWKDPKNTGGWNDYKNPNSSNWGGGRQEEKSSSSWNDSSSKDQGWGGRQPNQGWSSGKNGWGEEVDQAKNSNWESAGNKPASGWGEGGQNEIGTWGNGANTGSASKGGWDDCKRNSTWNETGRQPNSWNKQQQQQQQQQQETSGSWGPPPQTPSNGRPPNPNWNSGPQPAAPKDEEPSGWEEPSPQSISRKMDIDDGTSAWGDPSSYNYKNVNLWDKNSQGGQAPREQSLPTPMTSKSQASVWSKSTPPAPDNGTSAWGEPNETSPGWGEVDDTGASTTGWGNAPSNAPNAMKSSSKSMQDGWGESDGPVTGTRHSSWEEEEEGGVWNTAGSQGSSSSHNSTSWGQGGKKTQMKCSLKGGNSDSWMNPISKQFSNMGLLSQTEDIPGNKMDLSVGGLPDKKFEVDKRAMNLGDFNDIMRKDRSGFRPPNSKDMGTTDSGPYFEKGGNHGLFGNSTAQSRGMHTPVQPLNPSPNIRAQVPPQFLSPQVSASMLKQFPNSGLNPGLFNVGPQLSPQQIAMLSQLPQIPQFQLACQLLLQQQQQQQQLLQSQRKLSQAVRQQQEQQIARMVSALQQQQQRQPGMKHSPSHPVGPKPHIDSMVPNPLNVGLSDLQTKGQIPGYGSGFGSSSMDYGMVGGKEAGTESRFKQWTMMEGLPSVASQDANMHKNGAIVPPGKARGGSPYNQFDIIQGDPLGGHAGPAGDSWLPAKSPPTNKIGSKSSNASWPPEFQPGVPWKGIQNIDPESDPYVTPGSVLGGTATSPIVDTDHQLLRDNTTGSNSSLNTSLPSPGAWPYSASDNSFTNVHSTSAKFSDYKSTWSPDPIGHNPTHLSNKMWKNHISSRNTTGLPRPPPGLTNPKPSSPWNSTAPRSVRGWGAQDSRLASASTWSDGSSVRPSYWLVLHNLTPQIDGSTLRTICMQHGPLLTFHLNLTQGTALIRYNTKQEAAKAQTALHMCVLGNTTILAEFATDEEVSRFLTQAQPPTPAATPSAPTAGWQSLETGQNQTDPVGPALNLFGGSTGLGQWSSGGGGSSGGDLTGASLWGPPNYSSSLWGVPSVEDPHRMGSPAPLLPGDLLGGGSDSI", "length": 1682, "header": "tr|A0A8V0YC84-1|A0A8V0YC84_CHICK Computationally mapped isoform of Trinucleotide repeat containing adaptor 6B OS=Gallus gallus OX=9031 GN= PE=1 SV=1 CANONICAL=A0A8V0YHR3-1" }, "locus": { "chromosome": "1", "start_pos": 50197730, "end_pos": 50159476, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031511.1", "url": "https://www.ensembl.org/id/ENSGALT00010031511.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018405.1", "url": "https://www.ensembl.org/id/ENSGALP00010018405.1" } ] } }, { "isoform_ac": "A0A8V0YC94-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHR3/entry#A0A8V0YC94-1", "sequence": { "sequence": "MREKYWRKAVPREKEQEREEQLMEDKKRKKEDKKKKESAQKVTDQKTKVPEVTKPSLSQPVAASPIGNSPSPPVNGGNNAKRVAVPNGQPPSAARYMPREVPPRFRCQQDHKVLLKRGQPPPPSCMLLGGGAGPPPPTAPGANPNNAQPVTGALLQSDSGTATDSTIGGAAASNYANSTWGPGASSSSGTNANPTHIWDKVIVDGSDMEEWPCIASKDAESSSENTTDNNSASNPGLEKNTLPGSTTSNKGKGSQCQSGSAGNECNLGAWKSDPKAKSVQSSNPATESNSGLSNWRNLTGQDRIGSGSGFSNFNPNSNPSAWPALVQEGNSRKGTSESDSGSSNAQISTVGQTSREQQSKMENAGVNFVSGREQAQIHNTDGPKNGNTNSLNLSSPNPMENKGMPFEMGLGNPSRSTDTPSQSTGERKTGSVGSWGTARGSSGTDTVSGQSNSGNHGNNGKDREDSWKGASVQKPNGSRSDSWDNNNRSTGGGSWNFGPQHANESKWGEGNKLTSGVSQGEWKQLSGSDELKIGEWSGPNQPNSSTGAWDNQKGHPLPENQGNSQAPCWGRSSSSAGSEVGGQSTGSNHKAGSSDSHNSGRRSYRPTHPDCQAVLQTLLSRTDLDPRVLSNTGWGQTQIKQDTVWDIEEMPRSEGKSDKGTEGWESSATQTKNSGGWGDVPSQSNQIKSGWGELSTPTEWKDPKNTGGWNDYKNPNSSNWGGGRQEEKSSSSWNDSSSKDQGWGGRQPNQGWSSGKNGWGEEVDQAKNSNWESAGNKPASGWGEGGQNEIGTWGNGANTGSASKGGWDDCKRNSTWNETGRQPNSWNKQQQQQQQQQQETSGSWGPPPQTPSNGRPPNPNWNSGPQPAAPKDEEPSGWEEPSPQSISRKMDIDDGTSAWGDPSSYNYKNVNLWDKNSQGGQAPREQSLPTPMTSKSQASVWSKSTPPAPDNGTSAWGEPNETSPGWGEVDDTGASTTGWGNAPSNAPNAMKSSSKSMQDGWGESDGPVTGTRHSSWEEEEEGGVWNTAGSQGSSSSHNSTSWGQGGKKTQMKCSLKGGNSDSWMNPISKQFSNMGLLSQTEDIPGNKMDLSVGGLPDKKFEVDKRAMNLGDFNDIMRKDRSGFRPPNSKDMGTTDSGPYFEKGGNHGLFGNSTAQSRGMHTPVQPLNPSPNIRAQVPPQFLSPQVSASMLKQFPNSGLNPGLFNVGPQLSPQQIAMLSQLPQIPQFQLACQLLLQQQQQQQQLLQSQRKLSQAVRQQQEQQIARMVSALQQQQQRQPGMKHSPSHPVGPKPHIDSMVPNPLNVGLSDLQTKGQIPGYGSGFGSSSMDYGMVGGKEAGTESRFKQWTMMEGLPSVASQDANMHKNGAIVPPGKARGGSPYNQFDIIQGDPLGGHAGPAGDSWLPAKSPPTNKIGSKSSNASWPPEFQPGVPWKGIQNIDPESDPYVTPGSVLGGTATSPIVDTDHQLLRDNTTGSNSSLNTSLPSPGAWPYSASDNSFTNVHSTSAKFSDYKSTWSPDPIGHNPTHLSNKMWKNHISSRNTTGLPRPPPGLTNPKPSSPWNSTAPRSVRGWGAQDSRLASASTWSDGSSVRPSYWLVLHNLTPQIDGSTLRTICMQHGPLLTFHLNLTQGTALIRYNTKQEAAKAQTALHMCVLGNTTILAEFATDEEVSRFLTQAQPPTPAATPSAPTAGWQSLETGQNQTDPVGPALNLFGGSTGLGQWSSGGGGSSGGDLTGASLWGPPNYSSSLWGVPSVEDPHRMGSPAPLLPGDLLGGGSDSI", "length": 1778, "header": "tr|A0A8V0YC94-1|A0A8V0YC94_CHICK Computationally mapped isoform of Trinucleotide repeat containing adaptor 6B OS=Gallus gallus OX=9031 GN= PE=1 SV=1 CANONICAL=A0A8V0YHR3-1" }, "locus": { "chromosome": "1", "start_pos": 50266466, "end_pos": 50159476, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031525.1", "url": "https://www.ensembl.org/id/ENSGALT00010031525.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018415.1", "url": "https://www.ensembl.org/id/ENSGALP00010018415.1" } ] } }, { "isoform_ac": "A0A8V0YHR3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHR3/entry#A0A8V0YHR3-1", "sequence": { "sequence": "MQTDEGEILEEGSPKMEHEDFVMEGHGKTPPPGEENKQEKEQEREEQLMEDKKRKKEDKKKKESAQKVTDQKTKVPEVTKPSLSQPVAASPIGNSPSPPVNGGNNAKRVAVPNGQPPSAARYMPREVPPRFRCQQDHKVLLKRGQPPPPSCMLLGGGAGPPPPTAPGANPNNAQPVTGALLQSDSGTATDSTIGGAAASNYANSTWGPGASSSSGTNANPTHIWDKVIVDGSDMEEWPCIASKDAESSSENTTDNNSASNPGLEKNTLPGSTTSNKGKGSQCQSGSAGNECNLGAWKSDPKAKSVQSSNPATESNSGLSNWRNLTGQDRIGSGSGFSNFNPNSNPSAWPALVQEGNSRKGTSESDSGSSNAQISTVGQTSREQQSKMENAGVNFVSGREQAQIHNTDGPKNGNTNSLNLSSPNPMENKGMPFEMGLGNPSRSTDTPSQSTGERKTGSVGSWGTARGSSGTDTVSGQSNSGNHGNNGKDREDSWKGASVQKPNGSRSDSWDNNNRSTGGGSWNFGPQHANESKWGEGNKLTSGVSQGEWKQLSGSDELKIGEWSGPNQPNSSTGAWDNQKGHPLPENQGNSQAPCWGRSSSSAGSEVGGQSTGSNHKAGSSDSHNSGRRSYRPTHPDCQAVLQTLLSRTDLDPRVLSNTGWGQTQIKQDTVWDIEEMPRSEGKSDKGTEGWESSATQTKNSGGWGDVPSQSNQIKSGWGELSTPTEWKDPKNTGGWNDYKNPNSSNWGGGRQEEKSSSSWNDSSSKDQGWGGRQPNQGWSSGKNGWGEEVDQAKNSNWESAGNKPASGWGEGGQNEIGTWGNGANTGSASKGGWDDCKRNSTWNETGRQPNSWNKQQQQQQQQQQETSGSWGPPPQTPSNGRPPNPNWNSGPQPAAPKDEEPSGWEEPSPQSISRKMDIDDGTSAWGDPSSYNYKNVNLWDKNSQGGQAPREQSLPTPMTSKSQASVWSKSTPPAPDNGTSAWGEPNETSPGWGEVDDTGASTTGWGNAPSNAPNAMKSSSKSMQDGWGESDGPVTGTRHSSWEEEEEGGVWNTAGSQGSSSSHNSTSWGQGGKKTQMKCSLKGGNSDSWMNPISKQFSNMGLLSQTEDIPGNKMDLSVGGLPDKKFEVDKRAMNLGDFNDIMRKDRSGFRPPNSKDMGTTDSGPYFEKLTLPFSNQDGCLGDEAPCSPFSPSPSYKLSPSGSTLSNVGLGAIGSGLSPQNYAARQGGNHGLFGNSTAQSRGMHTPVQPLNPSPNIRAQVPPQFLSPQVSASMLKQFPNSGLNPGLFNVGPQLSPQQIAMLSQLPQIPQFQLACQLLLQQQQQQQQLLQSQRKLSQAVRQQQEQQIARMVSALQQQQQRQPGMKHSPSHPVGPKPHIDSMVPNPLNVGLSDLQTKGQIPGYGSGFGSSSMDYGMVGGKEAGTESRFKQWTMMEGLPSVASQDANMHKNGAIVPPGKARGGSPYNQFDIIQGDPLGGHAGPAGDSWLPAKSPPTNKIGSKSSNASWPPEFQPGVPWKGIQNIDPESDPYVTPGSVLGGTATSPIVDTDHQLLRDNTTGSNSSLNTSLPSPGAWPYSASDNSFTNVHSTSAKFSDYKSTWSPDPIGHNPTHLSNKMWKNHISSRNTTGLPRPPPGLTNPKPSSPWNSTAPRSVRGWGAQDSRLASASTWSDGSSVRPSYWLVLHNLTPQIDGSTLRTICMQHGPLLTFHLNLTQGTALIRYNTKQEAAKAQTALHMCVLGNTTILAEFATDEEVSRFLTQAQPPTPAATPSAPTAGWQSLETGQNQTDPVGPALNLFGGSTGLGQWSSGGGGSSGGDLTGASLWGPPNYSSSLWGVPSVEDPHRMGSPAPLLPGDLLGGGSDSI", "length": 1861, "header": "tr|A0A8V0YHR3-1|A0A8V0YHR3_CHICK Isoform 1 of Trinucleotide repeat containing adaptor 6B OS=Gallus gallus OX=9031 GN= PE=1 SV=1 CANONICAL=A0A8V0YHR3-1" }, "locus": { "chromosome": "1", "start_pos": 50266476, "end_pos": 50159476, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031519.1", "url": "https://www.ensembl.org/id/ENSGALT00010031519.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018409.1", "url": "https://www.ensembl.org/id/ENSGALP00010018409.1" } ] } }, { "isoform_ac": "A0A8V0YIM3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHR3/entry#A0A8V0YIM3-1", "sequence": { "sequence": "MREKEQEREEQLMEDKKRKKEDKKKKESAQKVTDQKTKVPEVTKPSLSQPVAASPIGNSPSPPVNGGNNAKRVAVPNGQPPSAARYMPREVPPRFRCQQDHKVLLKRGQPPPPSCMLLGGGAGPPPPTAPGANPNNAQPVTGALLQSDSGTATDSTIGGAAASNYANSTWGPGASSSSGTNANPTHIWDKVIVDGSDMEEWPCIASKDAESSSENTTDNNSASNPGLEKNTLPGSTTSNKGKGSQCQSGSAGNECNLGAWKSDPKAKSVQSSNPATESNSGLSNWRNLTGQDRIGSGSGFSNFNPNSNPSAWPALVQEGNSRKGTSESDSGSSNAQISTVGQTSREQQSKMENAGVNFVSGREQAQIHNTDGPKNGNTNSLNLSSPNPMENKGMPFEMGLGNPSRSTDTPSQSTGERKTGSVGSWGTARGSSGTDTVSGQSNSGNHGNNGKDREDSWKGASVQKPNGSRSDSWDNNNRSTGGGSWNFGPQHANESKWGEGNKLTSGVSQGEWKQLSGSDELKIGEWSGPNQPNSSTGAWDNQKGHPLPENQGNSQAPCWGRSSSSAGSEVGGQSTGSNHKAGSSDSHNSGRRSYRPTHPDCQAVLQTLLSRTDLDPRVLSNTGWGQTQIKQDTVWDIEEMPRSEGKSDKGTEGWESSATQTKNSGGWGDVPSQSNQIKSGWGELSTPTEWKDPKNTGGWNDYKNPNSSNWGGGRQEEKSSSSWNDSSSKDQGWGGRQPNQGWSSGKNGWGEEVDQAKNSNWESAGNKPASGWGEGGQNEIGTWGNGANTGSASKGGWDDCKRNSTWNETGRQPNSWNKQQQQQQQQQQETSGSWGPPPQTPSNGRPPNPNWNSGPQPAAPKDEEPSGWEEPSPQSISRKMDIDDGTSAWGDPSSYNYKNVNLWDKNSQGGQAPREQSLPTPMTSKSQASVWSKSTPPAPDNGTSAWGEPNETSPGWGEVDDTGASTTGWGNAPSNAPNAMKSSSKSMQDGWGESDGPVTGTRHSSWEEEEEGGVWNTAGSQGSSSSHNSTSWGQGGKKTQMKCSLKGGNSDSWMNPISKQFSNMGLLSQTEDIPGNKMDLSVGGLPDKKFEVDKRAMNLGDFNDIMRKDRSGFRPPNSKDMGTTDSGPYFEKGGNHGLFGNSTAQSRGMHTPVQPLNPSPNIRAQVPPQFLSPQVSASMLKQFPNSGLNPGLFNVGPQLSPQQIAMLSQLPQIPQFQLACQLLLQQQQQQQQLLQSQRKLSQAVRQQQEQQIARMVSALQQQQQRQPGMKHSPSHPVGPKPHIDSMVPNPLNVGLSDLQTKGQIPGYGSGFGSSSMDYGMVGGKEAGTESRFKQWTMMEGLPSVASQDANMHKNGAIVPPGKARGGSPYNQFDIIQGDPLGGHAGPAGDSWLPAKSPPTNKIGSKSSNASWPPEFQPGVPWKGIQNIDPESDPYVTPGSVLGGTATSPIVDTDHQLLRDNTTGSNSSLNTSLPSPGAWPYSASDNSFTNVHSTSAKFSDYKSTWSPDPIGHNPTHLSNKMWKNHISSRNTTGLPRPPPGLTNPKPSSPWNSTAPRSVRGWGAQDSRLASGEKDHLITPLIRPEECAFYSTNGLEERKLQLPASTWSDGSSVRPSYWLVLHNLTPQIDGSTLRTICMQHGPLLTFHLNLTQGTALIRYNTKQEAAKAQTALHMCVLGNTTILAEFATDEEVSRFLTQAQPPTPAATPSAPTAGWQSLETGQNQTDPVGPALNLFGGSTGLGQWSSGGGGSSGGDLTGASLWGPPNYSSSLWGVPSVEDPHRMGSPAPLLPGDLLGGGSDSI", "length": 1800, "header": "tr|A0A8V0YIM3-1|A0A8V0YIM3_CHICK Computationally mapped isoform of Trinucleotide repeat containing adaptor 6B OS=Gallus gallus OX=9031 GN= PE=1 SV=1 CANONICAL=A0A8V0YHR3-1" }, "locus": { "chromosome": "1", "start_pos": 50233434, "end_pos": 50159476, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031515.1", "url": "https://www.ensembl.org/id/ENSGALT00010031515.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018407.1", "url": "https://www.ensembl.org/id/ENSGALP00010018407.1" } ] } }, { "isoform_ac": "A0A8V0YIM8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHR3/entry#A0A8V0YIM8-1", "sequence": { "sequence": 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"length": 1751, "header": "tr|A0A8V0YKM5-1|A0A8V0YKM5_CHICK Computationally mapped isoform of Trinucleotide repeat containing adaptor 6B OS=Gallus gallus OX=9031 GN= PE=1 SV=1 CANONICAL=A0A8V0YHR3-1" }, "locus": { "chromosome": "1", "start_pos": 50266476, "end_pos": 50159476, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031523.1", "url": "https://www.ensembl.org/id/ENSGALT00010031523.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018413.1", "url": "https://www.ensembl.org/id/ENSGALP00010018413.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1529, "start_aa": "Thr", "end_pos": 1529, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1529", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 164, "start_aa": "Thr", "end_pos": 164, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr164", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1762, "start_aa": "Thr", "end_pos": 1762, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1762", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1766, "start_aa": "Thr", "end_pos": 1766, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1766", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1771, "start_aa": "Thr", "end_pos": 1771, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1771", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "R-GGA-426496", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-426496", "resource": "Reactome", "description": "Post-transcriptional silencing by small RNAs" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHR3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHR3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHR3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHR3" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHR3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHR3" } ], "pmid": "" }, { "name": "P-body", "id": "GO:0000932", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000932", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHR3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHR3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "regulation of translation", "id": "GO:0006417", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006417", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHR3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHR3" } ], "pmid": "" }, { "name": "positive regulation of nuclear-transcribed mRNA poly(A) tail shortening", "id": "GO:0060213", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060213", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHR3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHR3" } ], "pmid": "" }, { "name": "positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay", "id": "GO:1900153", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1900153", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHR3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHR3" } ], "pmid": "" }, { "name": "miRNA-mediated post-transcriptional gene silencing", "id": "GO:0035195", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035195", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHR3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHR3" } ], "pmid": "" }, { "name": "regulatory ncRNA-mediated gene silencing", "id": "GO:0031047", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031047", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHR3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHR3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1064, "end_pos": 1066, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1234, "end_pos": 1236, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1501, "end_pos": 1503, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1553, "end_pos": 1555, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1558, "end_pos": 1560, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1562, "end_pos": 1564, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1622, "end_pos": 1624, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1643, "end_pos": 1645, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1682, "end_pos": 1684, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1708, "end_pos": 1710, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1738, "end_pos": 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"length": 1116, "header": "tr|A0A8V0YHU8-1|A0A8V0YHU8_CHICK Isoform 1 of Ubiquitin associated protein 2 OS=Gallus gallus OX=9031 GN=UBAP2 PE=1 SV=1 CANONICAL=A0A8V0YHU8-1" }, "locus": { "chromosome": "Z", "start_pos": 8011561, "end_pos": 7807200, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027339.1", "url": "https://www.ensembl.org/id/ENSGALT00010027339.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015593.1", "url": "https://www.ensembl.org/id/ENSGALP00010015593.1" } ] } }, { "isoform_ac": "E1C5S0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHU8/entry#E1C5S0-1", "sequence": { "sequence": 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"length": 1109, "header": "tr|E1C5S0-1|E1C5S0_CHICK Computationally mapped isoform of Ubiquitin associated protein 2 OS=Gallus gallus OX=9031 GN=UBAP2 PE=1 SV=3 CANONICAL=A0A8V0YHU8-1" }, "locus": { "chromosome": "Z", "start_pos": 8011561, "end_pos": 7807200, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027338.1", "url": "https://www.ensembl.org/id/ENSGALT00010027338.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015592.1", "url": "https://www.ensembl.org/id/ENSGALP00010015592.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 616, "start_aa": "Thr", "end_pos": 616, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr616", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:407092", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:407092", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHU8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHU8" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHU8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHU8" } ], "pmid": "" }, { "name": "chromosome", "id": "GO:0005694", "url": 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CANONICAL=A0A8V0YHV0-1" }, "locus": { "chromosome": "Z", "start_pos": 22751872, "end_pos": 22716920, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029812.1", "url": "https://www.ensembl.org/id/ENSGALT00010029812.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017357.1", "url": "https://www.ensembl.org/id/ENSGALP00010017357.1" } ] } }, { "isoform_ac": "A0A8V0YHV0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHV0/entry#A0A8V0YHV0-1", "sequence": { "sequence": "MFPNSSNLGRPPFPPKHQQQNNFLNKVPLNIRPVLSHQQIINAQINFQNAILSRASLSGNLVATLGGTPQPLTYGNGSPVNASVPSPTFRGKKRLSEQSVPYDVKRQRYRSPRRETTVVSQAVPSPEESACLFSGSSPLFNVCYVPDLSICVPRLQDVSFPDVTETTLPVAKDKLSQQVLELFQACQQQTCDLNRKELCRSELQREIQRIFPCSRLFLVGSSLNGFGTRTSDGDLCLVIKEEPVNQKTEARHILSLVQKLFSTKLSSYIERPQLIRAKVPIVKFRDKVSCVEFDLNVNNIVGIRNTFLLRTYAYIEKRVRPLVLVVKKWASFHDINDASRGTLSSYSLVLMVLHYLQTLPEPILPSLQKNYPESFDPTMQLHLVHQAPCTIPPYLSKNESSLGELLIGFFKYYATEFEAVHEKQKFDTIKEEFLKSWQILRDKKDLSFVLPLRATIQRR", "length": 459, "header": "tr|A0A8V0YHV0-1|A0A8V0YHV0_CHICK Isoform 1 of polynucleotide adenylyltransferase OS=Gallus gallus OX=9031 GN=PAPD4 PE=3 SV=1 CANONICAL=A0A8V0YHV0-1" }, "locus": { "chromosome": "Z", "start_pos": 22751872, "end_pos": 22716920, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029824.1", "url": "https://www.ensembl.org/id/ENSGALT00010029824.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017367.1", "url": "https://www.ensembl.org/id/ENSGALP00010017367.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHV0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHV0" } ], "pmid": "" }, { "name": 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"pmid": "" } ] }, { "name": "Biological Process", "total": 7, "go_terms": [ { "name": "histone mRNA catabolic process", "id": "GO:0071044", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071044", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHV0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHV0" } ], "pmid": "" }, { "name": "mRNA 3'-end processing", "id": "GO:0031124", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031124", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHV0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHV0" } ], "pmid": "" }, { "name": "RNA 3'-end processing", "id": "GO:0031123", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031123", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHV0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHV0" } ], "pmid": "" }, { "name": "negative regulation of miRNA catabolic process", "id": "GO:2000626", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000626", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHV0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHV0" } ], "pmid": "" }, { "name": "target-directed miRNA degradation", "id": "GO:0140958", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140958", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHV0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHV0" } ], "pmid": "" }, { "name": "mRNA processing", "id": "GO:0006397", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006397", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHV0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHV0" } ], "pmid": "" }, { "name": "regulation of gene expression", "id": "GO:0010468", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010468", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHV0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHV0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 398, "end_pos": 400, "annotation": "n_glycosylation_sequon" }, { "start_pos": 4, "end_pos": 6, "annotation": "n_glycosylation_sequon" }, { "start_pos": 76, "end_pos": 78, "annotation": "n_glycosylation_sequon" }, { "start_pos": 81, "end_pos": 83, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "11332", "name": "", "equation": "RNA(n) + ATP = RNA(n)-3'-adenine ribonucleotide + diphosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YUZ1-1", "Q5ZL95-1", "A0A8V0X8P1-1", "A0A8V0YID1-1", "A0A8V0Z2C0-1", "A0A8V0YHV0-1", "F1N8K6-1", "A0A8V0X0M4-1", "A0A1D5PH78-1" ], "evidence": [ { "id": "11332", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/11332" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A1D5PH78", "gene_name": "PAPD5", "activity": [ { "ec_number": "2.7.7.19", "activity": "RNA(n) + ATP = RNA(n)-3'-adenine ribonucleotide + diphosphate.", "evidence": [ { "id": "A0A1D5PH78", "database": 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"A0A8V0YID1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YID1" } ] } ] }, { "uniprot_ac": "A0A8V0YUZ1", "gene_name": "PAPOLB", "activity": [ { "ec_number": "2.7.7.19", "activity": "RNA(n) + ATP = RNA(n)-3'-adenine ribonucleotide + diphosphate.", "evidence": [ { "id": "A0A8V0YUZ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUZ1" } ] }, { "ec_number": "2.7.7.19", "activity": "", "evidence": [ { "id": "A0A8V0YUZ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUZ1" } ] } ] }, { "uniprot_ac": "A0A8V0Z2C0", "gene_name": "PAPOLG", "activity": [ { "ec_number": "2.7.7.19", "activity": "RNA(n) + ATP = RNA(n)-3'-adenine ribonucleotide + diphosphate.", "evidence": [ { "id": "A0A8V0Z2C0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2C0" } ] }, { "ec_number": "2.7.7.19", "activity": "", "evidence": [ { "id": "A0A8V0Z2C0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2C0" } ] } ] }, { "uniprot_ac": "F1N8K6", "gene_name": "FAM46D", "activity": [ { "ec_number": "2.7.7.19", "activity": "RNA(n) + ATP = RNA(n)-3'-adenine ribonucleotide + diphosphate.", "evidence": [ { "id": "F1N8K6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N8K6" } ] }, { "ec_number": "2.7.7.19", "activity": "", "evidence": [ { "id": "F1N8K6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N8K6" } ] } ] }, { "uniprot_ac": "Q5ZL95", "gene_name": "TENT5C", "activity": [ { "ec_number": "2.7.7.19", "activity": "RNA(n) + ATP = RNA(n)-3'-adenine ribonucleotide + diphosphate.", "evidence": [ { "id": "Q5ZL95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZL95" } ] }, { "ec_number": "2.7.7.19", "activity": "", "evidence": [ { "id": "Q5ZL95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZL95" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YHV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHV0" }, { "id": "PF22600", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22600" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Poly(A) RNA polymerase mitochondrial-like central palm", "eco_id": "ECO_0000259", "start_pos": 175, "end_pos": 313, "start_aa": "Leu", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.7.7.19", "ec_name": "RNA(n) + ATP = RNA(n)-3'-adenine ribonucleotide + diphosphate.", "evidence": [ { "id": "2.7.7.19", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.19" }, { "id": "2.7.7.19", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.7.7.19" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 398, "end_pos": 400 }, { "start_pos": 4, "end_pos": 6 }, { "start_pos": 76, "end_pos": 78 }, { "start_pos": 81, "end_pos": 83 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YHW5-1", "uniprot_ac": "A0A8V0YHW5", "uniprot_id": "A0A8V0YHW5_CHICK", "mass": { "chemical_mass": 86322.0, "monoisotopic_mass": 86322.0 }, "refseq": { "ac": "NP_001012905", "name": "NF-kappa-B-repressing factor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012905" }, "gene_names": [ { "name": "NKRF", "type": "recommended", "evidence": [ { "id": "A0A8V0YHW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHW5" } ] }, { "name": "NKRF", "type": "synonym", "evidence": [ { "id": "NP_001012905", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012905" } ] } ], "protein_names": [ { "name": "NF-kappa-B-repressing factor", "type": "recommended", "evidence": [ { "id": "A0A8V0YHW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHW5/entry#names_and_taxonomy" } ] }, { "name": "NF-kappa-B-repressing factor", "type": "synonym", "evidence": [ { "id": "NP_001012905", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012905" } ] }, { "name": "NF-kappaB repressing factor", "type": "synonym", "evidence": [ { "id": "NP_001012905", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012905" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ720987.1, AJ727882.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000071.1. On Sep 23, 2021 this sequence version replaced NP_001012905.2. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001012905", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012905" } ] }, { "annotation": "Enhances the ATPase activity of DHX15 by acting like a brace that tethers mobile sections of DHX15 together, stabilizing a functional conformation with high RNA affinity of DHX15. Involved in the constitutive silencing of the interferon beta promoter, independently of the virus-induced signals, and in the inhibition of the basal and cytokine-induced iNOS promoter activity. Also involved in the regulation of IL-8 transcription. May also act as a DNA-binding transcription regulator: interacts with a specific negative regulatory element (NRE) 5'-AATTCCTCTGA-3' to mediate transcriptional repression of certain NK-kappa-B responsive genes.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YBI9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBI9#function" }, { "database": "UniProtKB", "id": "ARBA00055813", "url": "https://www.uniprot.org/uniprotkb/ARBA00055813#function" }, { "database": "UniProtKB", "id": "A0A8V0YHW5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHW5#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHW5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHW5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "NKRF", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHW5", "locus": { "chromosome": "4", "start_pos": 16501699, "end_pos": 16490260, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012977", "url": "https://www.ensembl.org/id/ENSGALG00010012977" } ] } } ], "crossref": [ { "id": "A0A8V0YHW5", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YHW5", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd02640", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02640", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "422370", "url": "https://www.ncbi.nlm.nih.gov/gene/422370", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000467", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000467", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001374", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001374", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014720", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014720", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR021859", "url": "https://www.ebi.ac.uk/interpro/entry/IPR021859", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034071", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034071", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036867", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036867", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR058828", "url": "https://www.ebi.ac.uk/interpro/entry/IPR058828", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:422370", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422370", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "SVLWTNH", "url": "https://omabrowser.org/oma/group/SVLWTNH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YBI9", "url": "https://www.orthodb.org/?gene=A0A8V0YBI9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YHW5", "url": "https://www.orthodb.org/?gene=A0A8V0YHW5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YPQ9", "url": "https://www.orthodb.org/?gene=A0A8V0YPQ9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16148", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16148", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16148:SF15", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16148:SF15", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01424", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01424", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01585", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01585", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF11952", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11952", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF26535", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF26535", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001012905", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012905", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YBI9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBI9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YBI9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBI9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHW5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHW5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHW5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHW5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YPQ9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPQ9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YPQ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPQ9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSPPPPEAVPEEVLEQWRQYSESERHWAVRRRFILRHLHSYPGAAIDQLLALSVLWSNHVFMGCRYGSQVMEKVLKMAEGIDIGEMQTFELVPSKKLKRQRSPPDSTERKEVPEPPKKVVPKFRVRPRFEPIHFVASAEKDGKKEDSLDSQTQETHQEANTNSVTQPAENCIDSHFENAQGVDTQISNSAGFGFASQAATPNKAVNSTDVATSGMLQVSVPPSAVQSVSETFPPSAIMLKQSFIEKLSAAVWKNLANPDANTGTDKINYTYLLTRSIQACKTNPEYIYVPLNEIAPADLPKSKKLLTDGFACEVRCQNVYLTTGYAGSKNGSRDRATELAVKLLQKSVEVRVVQRKFKHIYHEDLVVCLAGVSCPDFPPALKPHEEFVVANRDCVPAQPSTESAKGSTNTSKHWTSFVLTENASDAIGILNNSASYNKMSVEYKYDYMPNRMWRCRVYLQDHCLAEGYGTKKTSKHTAADEALKILQKTQSNLTAIKMTQVQKVGRSSQGSGRKKDLKDLVVYENSDNPVCTLNDTAQFNKMTVEYVFERMTGMRWKCKVLLENEFIAEAVGVKKSVKHEAAEEAVKILKKTQPTVVNNLKKGTIEDVISRNEIRGRSAEDALKQKIKEDNIGNQILRKMGWTGGGLGKDGEGIREPISVKEQFKREGLGLDVERVNKIAKRDIEQIIRNYAHSESHVDLTFSTELTNDERKQIHQIAQKYGLKSKSHGQGRDRYLVVSRKRRKEDLLDQLKQEGHVGHYELIMPQAN", "length": 768, "header": "tr|A0A8V0YHW5-1|A0A8V0YHW5_CHICK Isoform 1 of NF-kappa-B-repressing factor OS=Gallus gallus OX=9031 GN=NKRF PE=3 SV=1 CANONICAL=A0A8V0YHW5-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YBI9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHW5/entry#A0A8V0YBI9-1", "sequence": { "sequence": "MFCISNINDLVLFCGVCEAELSAWGRYGSQVMEKVLKMAEGIDIGEMQTFELVPSKKLKRQRSPPDSTERKEVPEPPKKVVPKFRVRPRFEPIHFVASAEKDGKKEDSLDSQTQETHQEANTNSVTQPAENCIDSHFENAQGVDTQISNSAGFGFASQAATPNKAVNSTDVATSGMLQVSVPPSAVQSVSETFPPSAIMLKQSFIEKLSAAVWKNLANPDANTGTDKINYTYLLTRSIQACKTNPEYIYVPLNEIAPADLPKSKKLLTDGFACEVRCQNVYLTTGYAGSKNGSRDRATELAVKLLQKSVEVRVVQRKFKHIYHEDLVVCLAGVSCPDFPPALKPHEEFVVANRDCVPAQPSTESAKGSTNTSKHWTSFVLTENASDAIGILNNSASYNKMSVEYKYDYMPNRMWRCRVYLQDHCLAEGYGTKKTSKHTAADEALKILQKTQSNLTAIKMTQVQKVGRSSQGSGRKKDLKDLVVYENSDNPVCTLNDTAQFNKMTVEYVFERMTGMRWKCKVLLENEFIAEAVGVKKSVKHEAAEEAVKILKKTQPTVVNNLKKGTIEDVISRNEIRGRSAEDALKQKIKEDNIGNQILRKMGWTGGGLGKDGEGIREPISVKEQFKREGLGLDVERVNKIAKRDIEQIIRNYAHSESHVDLTFSTELTNDERKQIHQIAQKYGLKSKSHGQGRDRYLVVSRKRRKEDLLDQLKQEGHVGHYELIMPQAN", "length": 729, "header": "tr|A0A8V0YBI9-1|A0A8V0YBI9_CHICK Computationally mapped isoform of NF-kappa-B-repressing factor OS=Gallus gallus OX=9031 GN=NKRF PE=4 SV=1 CANONICAL=A0A8V0YHW5-1" }, "locus": { "chromosome": "4", "start_pos": 16497811, "end_pos": 16493469, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031139.1", "url": "https://www.ensembl.org/id/ENSGALT00010031139.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018133.1", "url": "https://www.ensembl.org/id/ENSGALP00010018133.1" } ] } }, { "isoform_ac": "A0A8V0YHW5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHW5/entry#A0A8V0YHW5-1", "sequence": { "sequence": "MSPPPPEAVPEEVLEQWRQYSESERHWAVRRRFILRHLHSYPGAAIDQLLALSVLWSNHVFMGCRYGSQVMEKVLKMAEGIDIGEMQTFELVPSKKLKRQRSPPDSTERKEVPEPPKKVVPKFRVRPRFEPIHFVASAEKDGKKEDSLDSQTQETHQEANTNSVTQPAENCIDSHFENAQGVDTQISNSAGFGFASQAATPNKAVNSTDVATSGMLQVSVPPSAVQSVSETFPPSAIMLKQSFIEKLSAAVWKNLANPDANTGTDKINYTYLLTRSIQACKTNPEYIYVPLNEIAPADLPKSKKLLTDGFACEVRCQNVYLTTGYAGSKNGSRDRATELAVKLLQKSVEVRVVQRKFKHIYHEDLVVCLAGVSCPDFPPALKPHEEFVVANRDCVPAQPSTESAKGSTNTSKHWTSFVLTENASDAIGILNNSASYNKMSVEYKYDYMPNRMWRCRVYLQDHCLAEGYGTKKTSKHTAADEALKILQKTQSNLTAIKMTQVQKVGRSSQGSGRKKDLKDLVVYENSDNPVCTLNDTAQFNKMTVEYVFERMTGMRWKCKVLLENEFIAEAVGVKKSVKHEAAEEAVKILKKTQPTVVNNLKKGTIEDVISRNEIRGRSAEDALKQKIKEDNIGNQILRKMGWTGGGLGKDGEGIREPISVKEQFKREGLGLDVERVNKIAKRDIEQIIRNYAHSESHVDLTFSTELTNDERKQIHQIAQKYGLKSKSHGQGRDRYLVVSRKRRKEDLLDQLKQEGHVGHYELIMPQAN", "length": 768, "header": "tr|A0A8V0YHW5-1|A0A8V0YHW5_CHICK Isoform 1 of NF-kappa-B-repressing factor OS=Gallus gallus OX=9031 GN=NKRF PE=3 SV=1 CANONICAL=A0A8V0YHW5-1" }, "locus": { "chromosome": "4", "start_pos": 16497811, "end_pos": 16490311, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031137.1", "url": "https://www.ensembl.org/id/ENSGALT00010031137.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018130.1", "url": "https://www.ensembl.org/id/ENSGALP00010018130.1" } ] } }, { "isoform_ac": "A0A8V0YPQ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHW5/entry#A0A8V0YPQ9-1", "sequence": { "sequence": "MSPPPPEAVPEEVLEQWRQYSESERHWAVRRRFILRHLHSYPGAAIDQLLALSVLWSNHVFMGCRYGSQVMEKVLKMAEGIDIGEMQTFELVPSKKLKRQRSPPDSTERKEVPEPPKKVVPKFRVRPRFEPIHFVASAEKDGKKEDSLDSQTQETHQEANTNSVTQPAENCIDSHFENAQGVDTQISNSAGFGFASQAATPNKAVNSTDVATSGMLQVSVPPSAVQSVSETFPPSAIMLKQSFIEKLSAAVWKNLANPDANTGTDKINYTYLLTRSIQACKTNPEYIYVPLNEIAPADLPKSKKLLTDGFACEVRCQNVYLTTGYAGSKNGSRDRATELAVKLLQKSVEVRVVQRKFKHIYHEDLVVCLAGVSCPDFPPALKPHEEFVVANRDCVPAQPSTESAKGSTNTSKHWTSFVLTENASDAIGILNNSASYNKMSVEYKYDYMPNRMWRCRVYLQDHCLAEGYGTKKTSKHTAADEALKILQKTQSNLTAIKMTQVQKVGRSSQGSGRKKDLKDLVVYENSDNPVCTLNDTAQFNKMTVEYVFERMTGMRWKCKVLLENEFIAEAVGVKKSVKHEAAEEAVKILKKTQPTVVNNLKKGTIEDVISRNEIRGRSAEDALKQKIKEDNIGNQILRKMGWTGGGLGKDGEGIREPISVKEQFKREGLGLDVERGNSQGNGRIALKCGASLASRWCWSVLLESGVLLLPGKQAVLLPVPFLQQGHEMELCEPWGSTHIVPGKRG", "length": 745, "header": "tr|A0A8V0YPQ9-1|A0A8V0YPQ9_CHICK Computationally mapped isoform of NFKB repressing factor OS=Gallus gallus OX=9031 GN=NKRF PE=3 SV=1 CANONICAL=A0A8V0YHW5-1" }, "locus": { "chromosome": "4", "start_pos": 16498972, "end_pos": 16490311, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031140.1", "url": "https://www.ensembl.org/id/ENSGALT00010031140.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018134.1", "url": "https://www.ensembl.org/id/ENSGALP00010018134.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:422370", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422370", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0R4IUL8-1", "protein_name": "NF-kappa-B-repressing factor", "gene_name": "nkrf", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLRPHSPDQFVSSKPAGFRRWTCNVDDFRQQFESDKHWSARRQFILKHIEQYEHENGLDKLLALSMVWVNHVFLGCRYGSQLMDKVLEMAEGIDLGEMPSYELVPNAEAKKRPCSSDGSEEPMSKMPVSKFTCRPRFEPVHFVSGESSGSGNGRTDEKENEKTRRRDEVTDARQKEPDHQAYNGNRGRTPPSSSLDKGRYGYDSWPEHRSKDVPSGGTSGLGYSSSGSTSNFMGKVQQEYTAKYEAHNSRQSDSVLQAGRSDGSGRSGTYESGRRGLGFGHQERPTSSKAFSRAYDGPSRGGTGLLPTPSLPASVPTAAVEEKQRLIVRVASAVAVTLRDPAFVGGPEGPNYNFILSRSIQACKTNPEYIYVNLRDIPPADLPKNRKVPCDGYACELRCQSVYLATGYSGSKNGARDRASEQAIKLFMRPVEIRILRRVYKRRYVNDMVVCQVNTPNPSLPPPLRNPEDSPPPSTKGQYVPDRSKHWTEFVIMENAHDAICILNNSAAFNRMKVDYTFDPVPNSNLWLCNVYLQGELVAQARGTKKSAKHSAAEEAVKKLRMNQAARQQEQQQQQQQQQQQQQQFSGGNYFSEESAGCYSQQSSSVAQLGELVILENSDNAICIINDTAQFNKVSAEYKFTVLADHSWRCEVYLDGQYVATGLGPKKTVKHIAAEEALATLRRTQAVVKSNLRKEGHADAISRDQIMCRSGEEAVRQEIKEDNIGNQLLRKMGWTGGGLGREGDGIAEPIKVKEQFTREGLGMDMDRHGSQLTKRDIEDIIRNYASSERQDDLRFSTELNNEERRQIHQVSQRYGLRSKSYGQGRQRFLVVSRRVQKEQLIGQLLQEGQVGRYELVKPQPL", "length": 861 }, "evidence": [ { "id": "A0A8V0YHW5", "url": "https://omabrowser.org/oma/group/A0A8V0YHW5/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A0U1RRZ3-1", "protein_name": "NF-kappa-B-repressing factor", "gene_name": "Nkrf", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAGGRLLLGGDFLSPPPLPPLPPPPPPLPPLPPPPPEPVLEQWRYSHESDWQWALRRSFICRHLHSYPGAALDQLLALSAAWTNHVFLGCRYSPRLMEKILHMAEGIDIGEMPSYDLMLPKPSKGQKRYLSTYDGQNPPKRQAGSKFHVRPRFEPVHFVASSSKAERQEDPYGPQTEEVNGRTHFASMPRNFYQDYTQDSFSIQDGNSQYCNSSGFIFTKDQPVATNMYFDSGNPAPSSASQQANCQPAPEPPPSQMYPESVVAEKQYFIEKLTATIWKNLSNPEMTSGSDKINYTYMLTRCIQACKTNPEYIYAPLKEIPPADIPKNKKLLTDGYACEVRCQNIYLSTGYAGSKNGSRDRATELAVKLLQKRIEVRVVRRKFKHIIGEDLVVCQIGVLSYEFPPALKPPEDLVVLGKDASGQPIFNSSAKHWTNFVITENANDAIGILNNSASFNKMSIEYKYEMMPNRTWRCRVFLQDHCLAEGYGTKKTSKHAAADEALKVLQKTQPTYSSVKSSQCHSGSSPKGSGKKKDIKDLVVYENSSNPVCTLNDTAQFNRMTVEYVYERMTGLRWKCKVILESEVIAEAVGVKKSVKYEAAGEAVKTLKKTQPTVINNLKKGTVEDVISRNEIQGRSAEEAYKQQIKEDNIGNQLLRKMGWTGGGLGKSGEGIREPISVKEQHKREGLGLDVERVNKIAKRDIEQIIRNYARSESHSDLTFSTELTNDERKQIHQIAQKYGLKSKSHGVGHDRYLVVGRKRRKEDLLDQLKQEGQVGHYELVMPQAN", "length": 786 }, "evidence": [ { "id": "A0A8V0YHW5", "url": "https://omabrowser.org/oma/group/A0A8V0YHW5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A3Q1MAF5-1", "protein_name": "NF-kappa-B-repressing factor", "gene_name": "NKRF", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAGGRLLLGGDFLSPPPLPPLPPPPPPPLPPPPPEPVLEQWRYSHESDWQWALRRSFICRHLHSYPGAALDQLLALSAAWTNHVFLGCRYSPRLMEKILQMAEGIDIGEMPSYDLMLSKASKGQKRHLSTCDGQNPPKKQAGSKFHVRPRFEPVHFVASSSKDERQEDPYGPQAKERNEQTHFANVPRDIYQDYTQDSFSIQDGNSQYCDSSGFIFTKDKPVTANMYFDSGNPAPSSTSQQADSQSPPEPSPSQTFPESVVAEKQYFIEKLTATIWKNLSNPEMTSGSDKINYTYMLTRCIQACKTNPEYIYAPLKEIPPADIPKNKKLLTDGYACEVRCQNIYLTTGYAGSKNGSRDRATELAVKLLQKRIEVRVIRRKFKHTFGEDLVVCQIGMPSYDFPPALKPPEELVVLAKDASGQPIFNASAKHWTNFILTENANDAIGILNNSASYNKMSVEYKYEMMPNRTWRCRVFLQDHCLAEGYGTKKTSKHAAADEALKILQKTQPTYPSVKSSQCQAGSSPRGSGKKKDIKDLVVYENSSNPVCTLNDTAQFNRMTVEYVYERMTGLRWKCKVILESEVIAEAVGVKKTVKYEAAGEAVKTLKKTQPTVINNLKKGAIEDVISRNEIQGRSAEEAYKQQIKEDNIGNQLLRKMGWTGGGLGKSGEGIREPISVKEQHKREGLGLDVERVNKIAKRDIEQIIRNYARSESHTDLTFSTELTNDERKQIHQIAQKYGLKSKSHGVGHDRYLVVGRKRRKEDLLDQLKQEGQVGHYELVMPQAN", "length": 784 }, "evidence": [ { "id": "A0A8V0YHW5", "url": "https://omabrowser.org/oma/group/A0A8V0YHW5/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1RUA0-1", "protein_name": "NF-kappa-B-repressing factor", "gene_name": "NKRF", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAGGRLLLGGDFLSPPPLPPLPPPPLPPLPPPPPEPVLEQWRYSHESDWQWALRRSFICRHLHSYPGAALDQLLALSAAWTNHVFLGCRYSPRLMEKILQMAEGIDIGEMPSYDLMLSKPSKGQKRHLSTCDGQNPPKKQAGSKFHVRPRFEPVHFVASSSKDERQEDPYGPQTKEVNEQTHFASMPRDIYQDYTQDSFSIQDGNSQYCDSSGFIFTKDQPVTANMYFDSGNPAPSSTAQQANSQSASEPSPSQTFPESVVAEKQYFIEKLTATIWKNLSNPEMTSGSDKINYTYMLTRCIQACKTNPEYIYAPLKEIPPADIPKNKKLLTDGYACEVRCQNIYLTTGYAGSKNGSRDRATELAVKLLQKRIEVRVVRRKFKHTIGEDLVVCQVGMPSYEFPPALKPPEDLVVLAKDASGQPIFNASAKHWTNFILTENANDAIGILNNSASYNKMSVEYKYEMMPNRTWRCRVFLQDHCLAEGYGTKKTSKHAAADEALKILQKTQPTYPSVKSSQCQTGSSPRGSGKKKDIKDLVVYENSSNPVCTLNDTAQFNRMTVEYVYERMTGLRWKCKVILESEVIAEAVGVKKTVKYEAAGEAVKTLKKTQPTVINNLKKGAVEDVISRNEIQGRSAEEAYKQQIKEDNIGNQLLRKMGWTGGGLGKSGEGIREPISVKEQHKREGLGLDVERVNKIAKRDIEQIIRNYARSESHTDLTFSTELTNDERKQIHQIAQKYGLKSKSHGVGHDRYLVVGRKRRKEDLLDQLKQEGQVGHYELVMPQAN", "length": 784 }, "evidence": [ { "id": "A0A8V0YHW5", "url": "https://omabrowser.org/oma/group/A0A8V0YHW5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "O15226-1", "protein_name": "NF-kappa-B-repressing factor", "gene_name": "NKRF", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEKILQMAEGIDIGEMPSYDLVLSKPSKGQKRHLSTCDGQNPPKKQAGSKFHARPRFEPVHFVASSSKDERQEDPYGPQTKEVNEQTHFASMPRDIYQDYTQDSFSIQDGNSQYCDSSGFILTKDQPVTANMYFDSGNPAPSTTSQQANSQSTPEPSPSQTFPESVVAEKQYFIEKLTATIWKNLSNPEMTSGSDKINYTYMLTRCIQACKTNPEYIYAPLKEIPPADIPKNKKLLTDGYACEVRCQNIYLTTGYAGSKNGSRDRATELAVKLLQKRIEVRVVRRKFKHTFGEDLVVCQIGMSSYEFPPALKPPEDLVVLGKDASGQPIFNASAKHWTNFVITENANDAIGILNNSASFNKMSIEYKYEMMPNRTWRCRVFLQDHCLAEGYGTKKTSKHAAADEALKILQKTQPTYPSVKSSQCHTGSSPRGSGKKKDIKDLVVYENSSNPVCTLNDTAQFNRMTVEYVYERMTGLRWKCKVILESEVIAEAVGVKKTVKYEAAGEAVKTLKKTQPTVINNLKKGAVEDVISRNEIQGRSAEEAYKQQIKEDNIGNQLLRKMGWTGGGLGKSGEGIREPISVKEQHKREGLGLDVERVNKIAKRDIEQIIRNYARSESHTDLTFSRELTNDERKQIHQIAQKYGLKSKSHGVGHDRYLVVGRKRRKEDLLDQLKQEGQVGHYELVMPQAN", "length": 690 }, "evidence": [ { "id": "A0A8V0YHW5", "url": "https://omabrowser.org/oma/group/A0A8V0YHW5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8BY02-1", "protein_name": "NF-kappa-B-repressing factor", "gene_name": "Nkrf", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEKILHMAEGIDIGEMPSYDLMLPKPSKGQKRYLSTYDGQNPPKKQAGSKFHVRARFEPVHFVASSSKAERQEDPYGPQTKDVNGRTHFASMPRNFYQDYTQDSFSIQDGNSQYCNSSGFIFTKDQPVATNMYFDSGNPAPSSTSQQANCQPAPEPPPSQMYPESLVAEKQYFIEKLTATIWKNLSNPEMTSGSDKINYTYMLTRCIQACKTNPEYIYAPLKEIPPADIPKNKKLLTDGYACEVRCQNIYLTTGYAGSKNGSRDRATELAVKLLQKRIEVRVVRRKFKHIIGEDLVVCQIGMLSYEFPPALKPPEDLVVLGKDASGQPIFNSSAKHWTNFVITENANDAIGILNNSASFNKMSIEYKYEMMPNRTWRCRVFLQDHCLAEGYGTKKTSKHAAADEALKVLQKTQPTYPSVKSSQCHSGSSPKGSGKKKDIKDLVVYENSSNPVCTLNDTAQFNRMTVEYVYERMTGLRWKCKVILESEVIAEAVGVKKSVKYEAAGEAVKTLKKTQPTVINNLKKGTVEDVISRNEIQGRSAEEAYKQQIKEDNIGNQLLRKMGWTGGGLGKSGEGIREPISVKEQHKREGLGLDVERVNKIAKRDIEQIIRNYARSESHSDLTFSTELTNDERKQIHQIAQKYGLKSKSHGVGHDRYLVVGRKRRKEDLLDQLKQEGQVGHYELVMPQAN", "length": 690 }, "evidence": [ { "id": "A0A8V0YHW5", "url": "https://omabrowser.org/oma/group/A0A8V0YHW5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHW5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHW5" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHW5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHW5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHW5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHW5" } ], "pmid": "" }, { "name": "negative regulation of DNA-templated transcription", "id": "GO:0045892", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045892", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHW5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHW5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHW5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHW5" } ], "pmid": "" }, { "name": "ATPase activator activity", "id": "GO:0001671", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001671", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHW5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHW5" } ], "pmid": "" }, { "name": "DNA-binding transcription activator activity, RNA polymerase II-specific", "id": "GO:0001228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001228", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHW5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHW5" } ], "pmid": "" }, { "name": "nucleic acid binding", "id": "GO:0003676", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003676", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHW5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHW5" } ], "pmid": "" }, { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHW5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHW5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 206, "end_pos": 208, "annotation": "n_glycosylation_sequon" }, { "start_pos": 268, "end_pos": 270, "annotation": "n_glycosylation_sequon" }, { "start_pos": 330, "end_pos": 332, "annotation": "n_glycosylation_sequon" }, { "start_pos": 409, "end_pos": 411, "annotation": "n_glycosylation_sequon" }, { "start_pos": 422, "end_pos": 424, "annotation": "n_glycosylation_sequon" }, { "start_pos": 431, "end_pos": 433, "annotation": "n_glycosylation_sequon" }, { "start_pos": 492, "end_pos": 494, "annotation": "n_glycosylation_sequon" }, { "start_pos": 534, "end_pos": 536, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YHW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHW5" }, { "id": "PS50174", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50174" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-patch", "eco_id": "ECO_0000259", "start_pos": 629, "end_pos": 674, "start_aa": "Glu", "end_aa": "Glu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0YHW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHW5" }, { "id": "PS51061", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51061" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "R3H", "eco_id": "ECO_0000259", "start_pos": 678, "end_pos": 742, "start_aa": "Lys", "end_aa": "Arg", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0YHW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHW5" }, { "id": "PS51827", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51827" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "XRN2-binding (XTBD)", "eco_id": "ECO_0000259", "start_pos": 14, "end_pos": 102, "start_aa": "Leu", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 206, "end_pos": 208 }, { "start_pos": 268, "end_pos": 270 }, { "start_pos": 330, "end_pos": 332 }, { "start_pos": 409, "end_pos": 411 }, { "start_pos": 422, "end_pos": 424 }, { "start_pos": 431, "end_pos": 433 }, { "start_pos": 492, "end_pos": 494 }, { "start_pos": 534, "end_pos": 536 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", 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"table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YHW8-1", "uniprot_ac": "A0A8V0YHW8", "uniprot_id": "A0A8V0YHW8_CHICK", "mass": { "chemical_mass": 10520.0, "monoisotopic_mass": 10520.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "RING-type domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A8V0YHW8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHW8/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], 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} ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 153, "end_pos": 155, "annotation": "n_glycosylation_sequon" }, { "start_pos": 22, "end_pos": 24, "annotation": "n_glycosylation_sequon" }, { "start_pos": 284, "end_pos": 286, "annotation": "n_glycosylation_sequon" }, { "start_pos": 326, "end_pos": 328, "annotation": "n_glycosylation_sequon" }, { "start_pos": 419, "end_pos": 421, "annotation": "n_glycosylation_sequon" }, { "start_pos": 551, "end_pos": 553, "annotation": "n_glycosylation_sequon" }, { "start_pos": 643, "end_pos": 645, "annotation": "n_glycosylation_sequon" }, { "start_pos": 718, "end_pos": 720, "annotation": "n_glycosylation_sequon" }, { "start_pos": 964, "end_pos": 966, "annotation": "n_glycosylation_sequon" }, { "start_pos": 965, "end_pos": 967, "annotation": "n_glycosylation_sequon" }, { "start_pos": 976, "end_pos": 978, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], 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"start_pos": 551, "end_pos": 553 }, { "start_pos": 643, "end_pos": 645 }, { "start_pos": 718, "end_pos": 720 }, { "start_pos": 964, "end_pos": 966 }, { "start_pos": 965, "end_pos": 967 }, { "start_pos": 976, "end_pos": 978 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YHX2-1", "uniprot_ac": "A0A8V0YHX2", "uniprot_id": "A0A8V0YHX2_CHICK", "mass": { "chemical_mass": 71313.0, "monoisotopic_mass": 71313.0 }, "refseq": { "ac": "XP_025005729", "name": "SLAIN motif-containing protein-like isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025005729" }, "gene_names": [ { "name": "LOC100859468", "type": "recommended", "evidence": [ { "id": "A0A8V0YHX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHX2" } ] }, { "name": "LOC100859468", "type": "synonym", "evidence": [ { "id": "XP_025005729", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025005729" } ] } ], "protein_names": [ { "name": "SLAIN motif-containing protein-like", "type": "recommended", "evidence": [ { "id": "A0A8V0YHX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHX2/entry#names_and_taxonomy" } ] }, { "name": "SLAIN motif-containing protein-like isoform X1", "type": "synonym", "evidence": [ { "id": "XP_025005729", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025005729" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 1% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052535.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_025005729.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_025005729", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025005729" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHX2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHX2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LOC100859468", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHX2", "locus": {} } ], "crossref": [ { "id": "A0A8V0YHX2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YHX2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000037816", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000037816", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100859468", "url": "https://www.ncbi.nlm.nih.gov/gene/100859468", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR026179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:100859468", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100859468", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "NTEPGSC", "url": "https://omabrowser.org/oma/group/NTEPGSC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q2TZW1", "url": "https://www.orthodb.org/?gene=A0A3Q2TZW1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YHX2", "url": "https://www.orthodb.org/?gene=A0A8V0YHX2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YMP8", "url": "https://www.orthodb.org/?gene=A0A8V0YMP8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22406", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22406", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22406:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22406:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15301", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15301", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_025005729", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025005729", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q2TZW1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TZW1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2TZW1-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TZW1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHX2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHX2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHX2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHX2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YMP8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMP8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YMP8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMP8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MMVVPGSAPLIQQDRALEPELGRGPTQSSAMGPGTEPAPGEVGPELEEVRKLQELVRRLEIQNQHLRTRSRRSVLGTAVAGEMRAGVDNHESGLNGMEINNSINAMAEKQELQIMADLHSKLSKIRTEEGENNCFKKDIGAQTQYGCLAAPEELSADTCKVETKTDDNVRCSSRVDRSDGTELMGNPVVAGTESSVKINQQSPKEKRGDIESLLNNSALDEVKVLELENCNEEEDSWLYVSPRKSAVNQKTGSPLQWCRQVLDNPSPETEAACRTLLSRLDQASRWKNLYCSPLASPSAHNLNTETGSCSNALNSPGHLKSTNKALLTCGSSGYLSMHSALSSQSSVDSELSTSDDSISMGYKLQDLTDVQVMARLQEESLRQDCASSSASVSRRSSSASLHSLRRGTYSDQEFDTYSLEDEDDYDCSLSYRSAHRYSPSPLSSPRCQSPSSSADYSRASASRIRPPRRSVQSPMQDRLKYANSEEEMRHSMPNLARTSLRALESVRSSRSLESDLQVPSSRLSRIQQPSASLAPSKLRYSSSAGQSPLTVRQPMKAGSCTNSLLTPRQPVKACSYTAPVSGVRKPQASSLSTGSSSGSSTTRSMVTVAKNSPMKARTSVGGTSVPKSKLTPPSKRFLQSAKATPSTVDDSWKDGCY", "length": 657, "header": "tr|A0A8V0YHX2-1|A0A8V0YHX2_CHICK Isoform 1 of SLAIN motif-containing protein-like OS=Gallus gallus OX=9031 GN=LOC100859468 PE=3 SV=1 CANONICAL=A0A8V0YHX2-1" }, "isoforms": [ { "isoform_ac": "A0A3Q2TZW1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHX2/entry#A0A3Q2TZW1-1", "sequence": { "sequence": "MMVVPGSAPLIQQDRALEPELGRGPTQSSAMGPGTEPAPGEVGPELEEVRKLQELVRRLEIQNQHLRTRSRRSVLGTAVAGEMRAGVDNHESGLNGMEINNSINAMAEKQELQIMADLHSKLSKIRTEEGENNCFKKDIGAQTQYGCLAAPEELSADTCKVETKTDDNVRCSSRVDRSDGTELMGNPVVAGTESSVKINQQSPKEKRGDIESLLNNSALDEVKVLELENCNEEEDSWLYVSPRKSAVNQKTGSPLQWCRQVLDNPSPETEAACRTLLSRLDQGYLSMHSALSSQSSVDSELSTSDDSISMGYKLQDLTDVQVMARLQEESLRQDCASSSASVSRRSSSASLHSLRRGTYSDQEFDTYSLEDEDDYDCSLSYRSAHRYSPSPLSSPRCQSPSSSADYSRASASRIRPPRRSVQSPMQDRLKYANSEEEMRHSMPNLARTSLRALESVRSSRSLESDLQVPSSRLSRIQQPSASLAPSKLRYSSSAGQSPLTVRQPMKAGSCTNSLLTPRQPVKACSYTAPVSGVRKPQASSLSTGSSSGSSTTRSMVTVAKNSPMKARTSVGGTSVPKSKLTPPSKRFLQSAKATPSTVDDSWKDGCY", "length": 607, "header": "tr|A0A3Q2TZW1-1|A0A3Q2TZW1_CHICK Computationally mapped isoform of Uncharacterized protein OS=Gallus gallus OX=9031 GN=LOC100859468 PE=3 SV=1 CANONICAL=A0A8V0YHX2-1" }, "locus": { "chromosome": "4", "start_pos": 11173244, "end_pos": 11156875, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029878.1", "url": "https://www.ensembl.org/id/ENSGALT00010029878.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017399.1", "url": "https://www.ensembl.org/id/ENSGALP00010017399.1" } ] } }, { "isoform_ac": "A0A8V0YHX2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHX2/entry#A0A8V0YHX2-1", "sequence": { "sequence": "MMVVPGSAPLIQQDRALEPELGRGPTQSSAMGPGTEPAPGEVGPELEEVRKLQELVRRLEIQNQHLRTRSRRSVLGTAVAGEMRAGVDNHESGLNGMEINNSINAMAEKQELQIMADLHSKLSKIRTEEGENNCFKKDIGAQTQYGCLAAPEELSADTCKVETKTDDNVRCSSRVDRSDGTELMGNPVVAGTESSVKINQQSPKEKRGDIESLLNNSALDEVKVLELENCNEEEDSWLYVSPRKSAVNQKTGSPLQWCRQVLDNPSPETEAACRTLLSRLDQASRWKNLYCSPLASPSAHNLNTETGSCSNALNSPGHLKSTNKALLTCGSSGYLSMHSALSSQSSVDSELSTSDDSISMGYKLQDLTDVQVMARLQEESLRQDCASSSASVSRRSSSASLHSLRRGTYSDQEFDTYSLEDEDDYDCSLSYRSAHRYSPSPLSSPRCQSPSSSADYSRASASRIRPPRRSVQSPMQDRLKYANSEEEMRHSMPNLARTSLRALESVRSSRSLESDLQVPSSRLSRIQQPSASLAPSKLRYSSSAGQSPLTVRQPMKAGSCTNSLLTPRQPVKACSYTAPVSGVRKPQASSLSTGSSSGSSTTRSMVTVAKNSPMKARTSVGGTSVPKSKLTPPSKRFLQSAKATPSTVDDSWKDGCY", "length": 657, "header": "tr|A0A8V0YHX2-1|A0A8V0YHX2_CHICK Isoform 1 of SLAIN motif-containing protein-like OS=Gallus gallus OX=9031 GN=LOC100859468 PE=3 SV=1 CANONICAL=A0A8V0YHX2-1" }, "locus": { "chromosome": "4", "start_pos": 11173244, "end_pos": 11156875, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029872.1", "url": "https://www.ensembl.org/id/ENSGALT00010029872.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017394.1", "url": "https://www.ensembl.org/id/ENSGALP00010017394.1" } ] } }, { "isoform_ac": "A0A8V0YMP8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHX2/entry#A0A8V0YMP8-1", "sequence": { "sequence": "MMVVPGSAPLIQQDRALEPELGRGPTQSSAMGPGTEPAPGEVGPELEEVRKLQELVRRLEIQNQHLRTRSRRSVLGTAVAGEMRAGVDNHESGLNGMEINNSINAMAEKQELQIMADLHSKLSKIRTEEGENNCFKKDIGAQTQYGCLAAPEELSADTCKVETKTDDNVRCSSRVDRSDGTELMGNPVVAGTESSVKINQQSPKEKRGDIESLLNNSALDEVKVLELENCNEEEDSWLYVSPRKSAVNQKTGSPLQWCRQVLDNPSPETEAACRTLLSRLDQASRWKNLYCSPLASPSAHNLNTETGSCSNALNSPGHLKSTNKALLTCGSSGYLSMHSALSSQSSVDSELSTSDDSISMGYKLQDLTDVQVMARLQEESLRQDCASSSASVSRRSSSASLHSLRRGTYSDQEFDTYSLEDEDDYDCSLSYRSAHRYSPSPLSSPRCQSPSSSADYSRASASRIRPPRRSVQSPMQDRLKYANSEEEMRHSMPNLARTSLRALESVRSSRSLESDLQVPSSRLSRIQQPSASLAPSKLRYSSSAGQSPLTVRQPMKAGSCTNSLLTPRQPVKACSYTAPVSGVRKPQASSLSTGSSSGSSTTRSMVTVAKNSPMKARTSVGGTSVPKSKLTPPSKRCPFVALS", "length": 643, "header": "tr|A0A8V0YMP8-1|A0A8V0YMP8_CHICK Computationally mapped isoform of SLAIN motif-containing protein-like OS=Gallus gallus OX=9031 GN=LOC100859468 PE=3 SV=1 CANONICAL=A0A8V0YHX2-1" }, "locus": { "chromosome": "4", "start_pos": 11173244, "end_pos": 11157304, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029870.1", "url": "https://www.ensembl.org/id/ENSGALT00010029870.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017392.1", "url": "https://www.ensembl.org/id/ENSGALP00010017392.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 26, "start_aa": "Thr", "end_pos": 26, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr26", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 644, "start_aa": "Thr", "end_pos": 644, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr644", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:100859468", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100859468", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "microtubule nucleation", "id": "GO:0007020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHX2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHX2" } ], "pmid": "" }, { "name": "positive regulation of microtubule polymerization", "id": "GO:0031116", "url": 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"sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 26, 644 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 100, "end_pos": 102 }, { "start_pos": 215, "end_pos": 217 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { 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"locus": { "chromosome": "13", "start_pos": 1445929, "end_pos": 1442149, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027370.1", "url": "https://www.ensembl.org/id/ENSGALT00010027370.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015624.1", "url": "https://www.ensembl.org/id/ENSGALP00010015624.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHX4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHX4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "cell adhesion", "id": "GO:0007155", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007155", "evidence": [ { 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"site_annotation": [ { "start_pos": 408, "end_pos": 410, "annotation": "n_glycosylation_sequon" }, { "start_pos": 534, "end_pos": 536, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YHX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHX4" }, { "id": "PS50268", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50268" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Cadherin", "eco_id": "ECO_0000259", "start_pos": 75, "end_pos": 134, "start_aa": "Tyr", "end_aa": "Phe", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": 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This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_046764648", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046764648" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHY1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHY1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "C1QTNF6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHY1", "locus": { "chromosome": "1", "start_pos": 51485805, "end_pos": 51477513, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010014648", "url": "https://www.ensembl.org/id/ENSGALG00010014648" } ] } } ], "crossref": [ { "id": "A0A8V0YHY1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YHY1", "database": "AlphaFoldDB", "categories": [] }, { "id": "427908", "url": "https://www.ncbi.nlm.nih.gov/gene/427908", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001073", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001073", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008160", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008160", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008983", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008983", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050392", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050392", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:427908", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427908", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "GPCQTRF", "url": "https://omabrowser.org/oma/group/GPCQTRF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YHY1", "url": "https://www.orthodb.org/?gene=A0A8V0YHY1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YPD3", "url": "https://www.orthodb.org/?gene=A0A8V0YPD3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YPD7", "url": "https://www.orthodb.org/?gene=A0A8V0YPD7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15427", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15427", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15427:SF52", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15427:SF52", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00386", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00386", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01391", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01391", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_046764648", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046764648", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YHY1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHY1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHY1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHY1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YPD3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPD3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YPD3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPD3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YPD7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPD7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YPD7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPD7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGPEASSAGRGQPASSGAGEHSEEPSASRVTMDIIYLRTPLAFLLLPLVVLGAPTDELHLTEPAPGACRRCCDPPDSSADAPPPPSSHHHLPYPMPEIRPYINITILKGEKGDRGEPGMPGKWGKEGPRGERGAQGQKGSKGQMGTAGDSCKHQYAAFSVGRRKALHSSEGFQVLIFDTVFVNLYSHFDMFNGKFYCSVAGLYYFSLNVHTWNFKETYMHIMRNEEEAVILYAQPSDRSIMQSQSLMLDLQENDEVWVRLYKRERENAIYSDDVDVYITFNGYLVKPSLD", "length": 290, "header": "tr|A0A8V0YHY1-1|A0A8V0YHY1_CHICK Isoform 1 of C1q and TNF related 6 OS=Gallus gallus OX=9031 GN=C1QTNF6 PE=4 SV=1 CANONICAL=A0A8V0YHY1-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YHY1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHY1/entry#A0A8V0YHY1-1", "sequence": { "sequence": "MGPEASSAGRGQPASSGAGEHSEEPSASRVTMDIIYLRTPLAFLLLPLVVLGAPTDELHLTEPAPGACRRCCDPPDSSADAPPPPSSHHHLPYPMPEIRPYINITILKGEKGDRGEPGMPGKWGKEGPRGERGAQGQKGSKGQMGTAGDSCKHQYAAFSVGRRKALHSSEGFQVLIFDTVFVNLYSHFDMFNGKFYCSVAGLYYFSLNVHTWNFKETYMHIMRNEEEAVILYAQPSDRSIMQSQSLMLDLQENDEVWVRLYKRERENAIYSDDVDVYITFNGYLVKPSLD", "length": 290, "header": "tr|A0A8V0YHY1-1|A0A8V0YHY1_CHICK Isoform 1 of C1q and TNF related 6 OS=Gallus gallus OX=9031 GN=C1QTNF6 PE=4 SV=1 CANONICAL=A0A8V0YHY1-1" }, "locus": { "chromosome": "1", "start_pos": 51483205, "end_pos": 51480487, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010035141.1", "url": "https://www.ensembl.org/id/ENSGALT00010035141.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020497.1", "url": "https://www.ensembl.org/id/ENSGALP00010020497.1" } ] } }, { "isoform_ac": "A0A8V0YPD3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHY1/entry#A0A8V0YPD3-1", "sequence": { "sequence": "MDIIYLRTPLAFLLLPLVVLGAPTDELHLTEPAPGACRRCCDPPDSSADAPPPPSSHHHLPYPMPEIRPYINITILKGEKGDRGEPGMPGKWGKEGPRGERGAQGQKGSKGQMGTAGDSCKHQYAAFSVGRRKALHSSEGFQVLIFDTVFVNLYSHFDMFNGKFYCSVAGLYYFSLNVHTWNFKETYMHIMRNEEEAVILYAQPSDRSIMQSQSLMLDLQENDEDCSETGLQALERKKHAQSDAQD", "length": 246, "header": "tr|A0A8V0YPD3-1|A0A8V0YPD3_CHICK Computationally mapped isoform of C1q and TNF related 6 OS=Gallus gallus OX=9031 GN=C1QTNF6 PE=4 SV=1 CANONICAL=A0A8V0YHY1-1" }, "locus": { "chromosome": "1", "start_pos": 51485323, "end_pos": 51481610, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010035156.1", "url": "https://www.ensembl.org/id/ENSGALT00010035156.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020504.1", "url": "https://www.ensembl.org/id/ENSGALP00010020504.1" } ] } }, { "isoform_ac": "A0A8V0YPD7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHY1/entry#A0A8V0YPD7-1", "sequence": { "sequence": "MDIIYLRTPLAFLLLPLVVLGAPTDELHLTEPAPGACRRCCDPPDSSADAPPPPSSHHHLPYPMPEIRPYINITILKGEKGDRGEPGMPGKWGKEGPRGERGAQGQKGSKGQMGTAGDSCKHQYAAFSVGRRKALHSSEGFQVLIFDTVFVNLYSHFDMFNGKFYCSVAGLYYFSLNVHTWNFKETYMHIMRNEEEAVILYAQPSDRSIMQSQSLMLDLQENDEVWVRLYKRERENAIYSDDVDVYITFNGYLVKPSLD", "length": 259, "header": "tr|A0A8V0YPD7-1|A0A8V0YPD7_CHICK Computationally mapped isoform of C1q and TNF related 6 OS=Gallus gallus OX=9031 GN=C1QTNF6 PE=4 SV=1 CANONICAL=A0A8V0YHY1-1" }, "locus": { "chromosome": "1", "start_pos": 51483205, "end_pos": 51481610, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010035171.1", "url": "https://www.ensembl.org/id/ENSGALT00010035171.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020509.1", "url": "https://www.ensembl.org/id/ENSGALP00010020509.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:427908", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427908", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A2R9YJL0-1", "protein_name": "Complement C1q tumor necrosis factor-related protein 6", "gene_name": "c1qtnf6a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MFGFLLLACLFLHLVVSVPQPPCRRCCDHLPPLDDSASTREGMPAMPEVRTYINMTILKGDKGDRGERGTPGKTGIEGPQGQQGFEGPKGDKGQAGAPGDACKAQHSAFSVGRRKSLHSVDHYQALIFDNIFVNTPEHFDMFSGKFRCHIAGIYFFNVNIHTWNFKETYLHIMQNDNTKAIIYAQPSDRSIMQSQSVMLPLKESDEVWVRLFKHERENAIYSDDVDIYITFNGYLIKPDME", "length": 241 }, "evidence": [ { "id": "A0A8V0YHY1", "url": "https://omabrowser.org/oma/group/A0A8V0YHY1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q3T1I2-1", "protein_name": "Complement C1q tumor necrosis factor-related protein 6", "gene_name": "C1qtnf6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRVIMGTASLGSIWAVFLLPLVFGVPTEEPTFGESVASHLPKNCQRCCDPEDPLSPADTVNAVPPYVLPEVRPYINITILKGDKGDRGPSGTPGKPGKNGTRGDRGSQGIKGDKGQAGSPGSSCQTHYSAFSVGRKTGLHSSENFLSLLFDRVFVNTDGHFDMATGRFVAPLRGLYFFSLNVHSWNYKETYVHIVHNEQAVVILYAQPSERSIMQSQSVMLPLVPGDYVWVRLFKRERENGIYSDDMDTYITFSGHLIKAEDN", "length": 263 }, "evidence": [ { "id": "A0A8V0YHY1", "url": "https://omabrowser.org/oma/group/A0A8V0YHY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6IR41-1", "protein_name": "Complement C1q tumor necrosis factor-related protein 6", "gene_name": "C1qtnf6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRVIMGIASLGFLWAVFLLPLVFGVPTEETTFGESVASHLPKGCRRCCDPEDLMSSDDTVQAPVSPYVLPEVRPYINITILKGDKGDRGPTGTPGKPGKNGTRGDRGSQGVKGDKGQAGSPGSSCQTHYSAFSVGRKTGLHSSENFLSLLFDRVFVNTDGHFDMATGSFVAPLRGLYFFSLNVHSWNYKETYVHIVHNEQAVVILYAQPSERSIMQSQSVMLPLVPGDRVWVRLFKRERENGIYSDDVDTYITFSGHLIKAEDN", "length": 264 }, "evidence": [ { "id": "A0A8V0YHY1", "url": "https://omabrowser.org/oma/group/A0A8V0YHY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9BXI9-2", "protein_name": "Complement C1q tumor necrosis factor-related protein 6", "gene_name": "C1QTNF6", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MQWLRVRESPGEATGHRVTMGTAALGPVWAALLLFLLMCEIPMVELTFDRAVASGCQRCCDSEDPLDPAHVSSASSSGRPHALPEIRPYINITILKGDKGDPGPMGLPGYMGREGPQGEPGPQGSKGDKGEMGSPGAPCQKRFFAFSVGRKTALHSGEDFQTLLFERVFVNLDGCFDMATGQFAAPLRGIYFFSLNVHSWNYKETYVHIMHNQKEAVILYAQPSERSIMQSQSVMLDLAYGDRVWVRLFKRQRENAIYSNDFDTYITFSGHLIKAEDD", "length": 278 }, "evidence": [ { "id": "A0A8V0YHY1", "url": "https://omabrowser.org/oma/group/A0A8V0YHY1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHY1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHY1" } ], "pmid": "" }, { "name": "protein-containing complex", "id": "GO:0032991", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032991", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHY1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHY1" } ], "pmid": "" }, { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHY1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHY1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHY1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHY1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 103, "end_pos": 105, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YHY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHY1" }, { "id": "PS50871", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50871" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C1q", "eco_id": "ECO_0000259", "start_pos": 151, "end_pos": 290, "start_aa": "Cys", "end_aa": "Asp", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 103, "end_pos": 105 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YHY2-1", "uniprot_ac": "A0A8V0YHY2", "uniprot_id": "A0A8V0YHY2_CHICK", "mass": { "chemical_mass": 146169.0, "monoisotopic_mass": 146169.0 }, "refseq": { "ac": "XP_040523497", "name": "liprin-alpha-2 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040523497" }, "gene_names": [ { "name": "PPFIA2", "type": "recommended", "evidence": [ { "id": "A0A8V0YHY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHY2" } ] }, { "name": "PPFIA2", "type": "synonym", "evidence": [ { "id": "XP_040523497", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040523497" } ] } ], "protein_names": [ { "name": "PTPRF interacting protein alpha 2", "type": "synonym", "evidence": [ { "id": "A0A8V0YHY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHY2/entry#names_and_taxonomy" } ] }, { "name": "liprin-alpha-2 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_040523497", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040523497" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040523497", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040523497" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHY2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHY2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PPFIA2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHY2", "locus": { "chromosome": "1", "start_pos": 40292957, "end_pos": 40593913, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012450", "url": "https://www.ensembl.org/id/ENSGALG00010012450" } ] } } ], "crossref": [ { "id": "cd09562", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09562", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd09565", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09565", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd09568", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09568", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "417877", "url": "https://www.ncbi.nlm.nih.gov/gene/417877", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001660", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001660", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013761", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013761", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029515", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029515", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037620", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037620", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037621", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037621", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037622", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037622", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057892", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057892", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y9J4", "url": "https://www.orthodb.org/?gene=A0A8V0Y9J4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y9K4", "url": "https://www.orthodb.org/?gene=A0A8V0Y9K4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YHY2", "url": "https://www.orthodb.org/?gene=A0A8V0YHY2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YHY7", "url": "https://www.orthodb.org/?gene=A0A8V0YHY7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YMQ3", "url": "https://www.orthodb.org/?gene=A0A8V0YMQ3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YMR2", "url": "https://www.orthodb.org/?gene=A0A8V0YMR2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12587", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12587", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12587:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12587:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00536", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00536", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07647", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07647", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25526", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25526", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-181429", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-181429", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-181430", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-181430", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-212676", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-212676", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-264642", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-264642", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-388844", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-388844", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_040523497", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040523497", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Y9J4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9J4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y9J4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9J4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y9K4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9K4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y9K4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9K4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHY2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHY2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHY2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHY2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHY7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHY7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHY7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHY7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YMQ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMQ3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YMQ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMQ3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YMR2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMR2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YMR2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMR2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MMCEVMPTINEDTPMSQRGSQSSGSDSDSHFEQLMVNMLDERDRLLDTLRETQESLSLAQQRLQDVIYDRDSLQRQLNSALPQMTVAAGTSIENNIQRTISCPNEFAALTKELNACREQLLEKEEEISELKAERNNTRLLLEHLECLVSRHERSLRMTVVKRQAQSPSGVSSEVEVLKALKSLFEHHKALDEKVRERLRVSLERVSALEEELAAANQEIVALREQNAHIQRKIAAGEGPAESEHIEGVEPGQKVHEKRLSNGSIDSNDETSQVIELQELLEKQNYEMAQMKERMAALSSRVGEVEQEAETARKELIKTEEMNSKYQRDIREAMAQKEDMEERITTLEKRYLSAQRESTSIHDMNDKLENELANKEAILRQLEDKNRQLQERLELAEQKLQQTMRKAETLPEVEAELAQRIAALTKSDPTSSTSSGDYQYVMEAKLQEMISIRRKAEERHGNIEERMRHLEAQLEEKNQELQRARQREKMNEEHNKRLSDTVDRLLTESNERLQLHLKERMAALEEKNVLIQESESFRKNLEESLHDKERLAEEIEKLRSELDQMKLRAGSLIEPTLSRPHLDSSAELRYSVGSLVDSQSDYRSTKVIRRPRRGRMGVRRDEPKVKSLGDHEWNRTQQIGVLSSHPFESDTEMSDIDDDDRETLFSSMDLLSPSGHSDAQTLAMMLQEQLDAINKEIRLIQEEKESTELRAEEIENRVASVSLEGLNLARVHQGTSITGSVTASSLASSSPPSGHSTPKLTPRSPAREMDRMGVMTLPSDLRKHRRKIAVVEEDGREDKATIKCETSPPPTPRAIRMTHTLPSSYHNDARSSLPASLEAESIGLGSVSSSQDSLHKAPKKKGIKSSIGRLFGKKEKARLGQLRGYIETEAAAQESLGLGKLGTQAEKDRRLKKKHELLEEARRKGLPFAQWDGPTVVAWLELWLGMPAWYVAACRANVKSGAIMSALSDTEIQREIGISNPLHRLKLRLAIQEMVSLTSPSAPPTSRTPSGNVWVTHEEMENLAAPAKTKESEEGSWAQTLAYGDMNHEWIGNEWLPSLGLPQYRSYFMECLVDARMLDHLTKKDLRVHLKMVDSFHRTSLQYGIMCLKRLNYDRKELEKRREMSQHEIKDVLVWSNDRVIRWIQAIGLREYANNILESGVHGSLIALDENFDYSSLALLLQIPTQNTQARQILEREYNNLLALGTERRLEESDDKNFRRGPSWRRQFPPREVHGISMMPGSSETLPAGFRLTTTSGQSRKMATDVASSRLQRLDSSTVRTYSC", "length": 1283, "header": "tr|A0A8V0YHY2-1|A0A8V0YHY2_CHICK Isoform 1 of PTPRF interacting protein alpha 2 OS=Gallus gallus OX=9031 GN=PPFIA2 PE=3 SV=1 CANONICAL=A0A8V0YHY2-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Y9J4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHY2/entry#A0A8V0Y9J4-1", "sequence": { "sequence": "MMCEVMPTINEDTPMSQRGSQSSGSDSDSHFEQLMVNMLDERDRLLDTLRETQESLSLAQQRLQDVIYDRDSLQRQLNSALPQMTVAAGTSIENNIQRTISCPNEFAALTKELNACREQLLEKEEEISELKAERNNTRLLLEHLECLVSRHERSLRMTVVKRQAQSPSGVSSEVEVLKALKSLFEHHKALDEKVRERLRVSLERVSALEEELAAANQEIVALREQNAHIQRKIAAGEGPAESEHIEGVEPGQKVHEKRLSNGSIDSNDETSQVIELQELLEKQNYEMAQMKERMAALSSRVGEVEQEAETARKELIKTEEMNSKYQRDIREAMAQKEDMEERITTLEKRYLSAQRESTSIHDMNDKLENELANKEAILRQLEDKNRQLQERLELAEQKLQQTMRKAETLPEVEAELAQRIAALTKAEERHGNIEERMRHLEAQLEEKNQELQRARQREKMNEEHNKRLSDTVDRLLTESNERLQLHLKERMAALEEKNVLIQESESFRKNLEESLHDKERLAEEIEKLRSELDQMKLRAGSLIEPTLSRPHLDSSAELRYSVGSLVDSQSDYRSTKVIRRPRRGRMGVRRDEPKVKSLGDHEWNRTQQIGVLSSHPFESDTEMSDIDDDDRETLFSSMDLLSPSGHSDAQTLAMMLQEQLDAINKEIRLIQEEKESTELRAEEIENRVASVSLEGLNLARVHQGTSITGSVTASSLASSSPPSGHSTPKLTPRSPAREMDRMGVMTLPSDLRKHRRKIAVVEEDGREDKATIKCETSPPPTPRAIRMTHTLPSSYHNDARSSLPASLEAESIGLGSVSSSQDSLHKAPKKKGIKSSIGRLFGKKEKARLGQLRGYIETEAAAQESLGLGKLGTQAEKDRRLKKNISGHELLEEARRKGLPFAQWDGPTVVAWLELWLGMPAWYVAACRANVKSGAIMSALSDTEIQREIGISNPLHRLKLRLAIQEMVSLTSPSAPPTSRTKESEEGSWAQTLAYGDMNHEWIGNEWLPSLGLPQYRSYFMECLVDARMLDHLTKKDLRVHLKMVDSFHRTSLQYGIMCLKRLNYDRKELEKRREMSQHEIKDVLVWSNDRVIRWIQAIGLREYANNILESGVHGSLIALDENFDYSSLALLLQIPTQNTQASPLTLLLVNLYS", "length": 1154, "header": "tr|A0A8V0Y9J4-1|A0A8V0Y9J4_CHICK Computationally mapped isoform of PTPRF interacting protein alpha 2 OS=Gallus gallus OX=9031 GN=PPFIA2 PE=3 SV=1 CANONICAL=A0A8V0YHY2-1" }, "locus": { "chromosome": "1", "start_pos": 40582347, "end_pos": 40300235, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029866.1", "url": "https://www.ensembl.org/id/ENSGALT00010029866.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017391.1", "url": "https://www.ensembl.org/id/ENSGALP00010017391.1" } ] } }, { "isoform_ac": "A0A8V0Y9K4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHY2/entry#A0A8V0Y9K4-1", "sequence": { "sequence": "MMCEVMPTINEDTPMSQRGSQSSGSDSDSHFEQLMVNMLDERDRLLDTLRETQESLSLAQQRLQDVIYDRDSLQRQLNSALPQMTVAAGTSIENNIQRTISCPNEFAALTKELNACREQLLEKEEEISELKAERNNTRLLLEHLECLVSRHERSLRMTVVKRQAQSPSGVSSEVEVLKALKSLFEHHKALDEKVRERLRVSLERVSALEEELAAANQEIVALREQNAHIQRKIAAGEGPAESEHIEGVEPGQKVHEKRLSNGSIDSNDETSQVIELQELLEKQNYEMAQMKERMAALSSRVGEVEQEAETARKELIKTEEMNSKYQRDIREAMAQKEDMEERITTLEKRYLSAQRESTSIHDMNDKLENELANKEAILRQLEDKNRQLQERLELAEQKLQQTMRKAETLPEVEAELAQRIAALTKAEERHGNIEERMRHLEAQLEEKNQELQRARQREKMNEEHNKRLSDTVDRLLTESNERLQLHLKERMAALEEKNVLIQESESFRKNLEESLHDKERLAEEIEKLRSELDQMKLRAGSLIEPTLSRPHLDSSAELRYSVGSLVDSQSDYRSTKVIRRPRRGRMGVRRDEPKVKSLGDHEWNRTQQIGVLSSHPFESDTEMSDIDDDDRETLFSSMDLLSPSGHSDAQTLAMMLQEQLDAINKEIRLIQEEKESTELRAEEIENRVASVSLEGLNLARVHQGTSITGSVTASSLASSSPPSGHSTPKLTPRSPAREMDRMGVMTLPSDLRKHRRKIAVVEEDGREDKATIKCETSPPPTPRAIRMTHTLPSSYHNDARSSLPASLEAESIGLGSVSSSQDSLHKAPKKKGIKSSIGRLFGKKEKARLGQLRGYIETEAAAQESLGLGKLGTQAEKDRRLKKKHELLEEARRKGLPFAQWDGPTVVAWLELWLGMPAWYVAACRANVKSGAIMSALSDTEIQREIGISNPLHRLKLRLAIQEMVSLTSPSAPPTSRTPSGNVWVTHEEMENLAAPAKTKESEEGSWAQTLAYGDMNHEWIGNEWLPSLGLPQYRSYFMECLVDARMLDHLTKKDLRVHLKMVDSFHRTSLQYGIMCLKRLNYDRKELEKRREMSQHEIKDVLVWSNDRVIRWIQAIGLREYANNILESGVHGSLIALDENFDYSSLALLLQIPTQNTQARQILEREYNNLLALGTERRLEESDDKNFRRGPSWRRQFPPREVHGISMMPGSSETLPAGFRLTTTSGQSRKMATDGTKSFPHLQKAGGFP", "length": 1250, "header": "tr|A0A8V0Y9K4-1|A0A8V0Y9K4_CHICK Computationally mapped isoform of PTPRF interacting protein alpha 2 OS=Gallus gallus OX=9031 GN=PPFIA2 PE=3 SV=1 CANONICAL=A0A8V0YHY2-1" }, "locus": { "chromosome": "1", "start_pos": 40582347, "end_pos": 40299010, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029889.1", "url": "https://www.ensembl.org/id/ENSGALT00010029889.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017401.1", "url": "https://www.ensembl.org/id/ENSGALP00010017401.1" } ] } }, { "isoform_ac": "A0A8V0YHY2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHY2/entry#A0A8V0YHY2-1", "sequence": { "sequence": "MMCEVMPTINEDTPMSQRGSQSSGSDSDSHFEQLMVNMLDERDRLLDTLRETQESLSLAQQRLQDVIYDRDSLQRQLNSALPQMTVAAGTSIENNIQRTISCPNEFAALTKELNACREQLLEKEEEISELKAERNNTRLLLEHLECLVSRHERSLRMTVVKRQAQSPSGVSSEVEVLKALKSLFEHHKALDEKVRERLRVSLERVSALEEELAAANQEIVALREQNAHIQRKIAAGEGPAESEHIEGVEPGQKVHEKRLSNGSIDSNDETSQVIELQELLEKQNYEMAQMKERMAALSSRVGEVEQEAETARKELIKTEEMNSKYQRDIREAMAQKEDMEERITTLEKRYLSAQRESTSIHDMNDKLENELANKEAILRQLEDKNRQLQERLELAEQKLQQTMRKAETLPEVEAELAQRIAALTKSDPTSSTSSGDYQYVMEAKLQEMISIRRKAEERHGNIEERMRHLEAQLEEKNQELQRARQREKMNEEHNKRLSDTVDRLLTESNERLQLHLKERMAALEEKNVLIQESESFRKNLEESLHDKERLAEEIEKLRSELDQMKLRAGSLIEPTLSRPHLDSSAELRYSVGSLVDSQSDYRSTKVIRRPRRGRMGVRRDEPKVKSLGDHEWNRTQQIGVLSSHPFESDTEMSDIDDDDRETLFSSMDLLSPSGHSDAQTLAMMLQEQLDAINKEIRLIQEEKESTELRAEEIENRVASVSLEGLNLARVHQGTSITGSVTASSLASSSPPSGHSTPKLTPRSPAREMDRMGVMTLPSDLRKHRRKIAVVEEDGREDKATIKCETSPPPTPRAIRMTHTLPSSYHNDARSSLPASLEAESIGLGSVSSSQDSLHKAPKKKGIKSSIGRLFGKKEKARLGQLRGYIETEAAAQESLGLGKLGTQAEKDRRLKKKHELLEEARRKGLPFAQWDGPTVVAWLELWLGMPAWYVAACRANVKSGAIMSALSDTEIQREIGISNPLHRLKLRLAIQEMVSLTSPSAPPTSRTPSGNVWVTHEEMENLAAPAKTKESEEGSWAQTLAYGDMNHEWIGNEWLPSLGLPQYRSYFMECLVDARMLDHLTKKDLRVHLKMVDSFHRTSLQYGIMCLKRLNYDRKELEKRREMSQHEIKDVLVWSNDRVIRWIQAIGLREYANNILESGVHGSLIALDENFDYSSLALLLQIPTQNTQARQILEREYNNLLALGTERRLEESDDKNFRRGPSWRRQFPPREVHGISMMPGSSETLPAGFRLTTTSGQSRKMATDVASSRLQRLDSSTVRTYSC", "length": 1283, "header": "tr|A0A8V0YHY2-1|A0A8V0YHY2_CHICK Isoform 1 of PTPRF interacting protein alpha 2 OS=Gallus gallus OX=9031 GN=PPFIA2 PE=3 SV=1 CANONICAL=A0A8V0YHY2-1" }, "locus": { "chromosome": "1", "start_pos": 40582347, "end_pos": 40297535, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029898.1", "url": "https://www.ensembl.org/id/ENSGALT00010029898.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017404.1", "url": "https://www.ensembl.org/id/ENSGALP00010017404.1" } ] } }, { "isoform_ac": "A0A8V0YHY7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHY2/entry#A0A8V0YHY7-1", "sequence": { "sequence": "MMCEVMPTINEDTPMSQRGSQSSGSDSDSHFEQLMVNMLDERDRLLDTLRETQESLSLAQQRLQDVIYDRDSLQRQLNSALPQMTVAAGTSIENNIQRTISCPNEFAALTKELNACREQLLEKEEEISELKAERNNTRLLLEHLECLVSRHERSLRMTVVKRQAQSPSGVSSEVEVLKALKSLFEHHKALDEKVRERLRVSLERVSALEEELAAANQEIVALREQNAHIQRKIAAGEGPAESEHIEGVEPGQKVHEKRLSNGSIDSNDETSQVIELQELLEKQNYEMAQMKERMAALSSRVGEVEQEAETARKELIKTEEMNSKYQRDIREAMAQKEDMEERITTLEKRYLSAQRESTSIHDMNDKLENELANKEAILRQLEDKNRQLQERLELAEQKLQQTMRKAETLPEVEAELAQRIAALTKAEERHGNIEERMRHLEAQLEEKNQELQRARQREKMNEEHNKRLSDTVDRLLTESNERLQLHLKERMAALEEKNVLIQESESFRKNLEESLHDKERLAEEIEKLRSELDQMKLRAGSLIEPTLSRPHLDSSAELRYSVGSLVDSQSDYRSTKVIRRPRRGRMGVRRDEPKVKSLGDHEWNRTQQIGVLSSHPFESDTEMSDIDDDDRETLFSSMDLLSPSGHSDAQTLAMMLQEQLDAINKEIRLIQEEKESTELRAEEIENRVASVSLEGLNLARVHQGTSITGSVTASSLASSSPPSGHSTPKLTPRSPAREMDRMGVMTLPSDLRKHRRKIAVVEEDGREDKATIKCETSPPPTPRAIRMTHTLPSSYHNDARSSLPASLEAESIGLGSVSSSQDSLHKAPKKKGIKSSIGRLFGKKEKARLGQLRGYIETEAAAQESLGLGKLGTQAEKDRRLKKNISGHELLEEARRKGLPFAQWDGPTVVAWLELWLGMPAWYVAACRANVKSGAIMSALSDTEIQREIGISNPLHRLKLRLAIQEMVSLTSPSAPPTSRTTLAYGDMNHEWIGNEWLPSLGLPQYRSYFMECLVDARMLDHLTKKDLRVHLKMVDSFHRTSLQYGIMCLKRLNYDRKELEKRREMSQHEIKDVLVWSNDRVIRWIQAIGLREYANNILESGVHGSLIALDENFDYSSLALLLQIPTQNTQARQILEREYNNLLALGTERRLEESDDKNFRRGPSWRRQFPPREVHGISMMPGSSETLPAGFRLTTTSGQSRKMATDVASSRLQRLDSSTVRTYSC", "length": 1226, "header": "tr|A0A8V0YHY7-1|A0A8V0YHY7_CHICK Computationally mapped isoform of PTPRF interacting protein alpha 2 OS=Gallus gallus OX=9031 GN=PPFIA2 PE=3 SV=1 CANONICAL=A0A8V0YHY2-1" }, "locus": { "chromosome": "1", "start_pos": 40582347, "end_pos": 40297535, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029905.1", "url": "https://www.ensembl.org/id/ENSGALT00010029905.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017409.1", "url": "https://www.ensembl.org/id/ENSGALP00010017409.1" } ] } }, { "isoform_ac": "A0A8V0YMQ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHY2/entry#A0A8V0YMQ3-1", "sequence": { "sequence": 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"length": 1233, "header": "tr|A0A8V0YMQ3-1|A0A8V0YMQ3_CHICK Computationally mapped isoform of PTPRF interacting protein alpha 2 OS=Gallus gallus OX=9031 GN=PPFIA2 PE=3 SV=1 CANONICAL=A0A8V0YHY2-1" }, "locus": { "chromosome": "1", "start_pos": 40582347, "end_pos": 40297535, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029875.1", "url": "https://www.ensembl.org/id/ENSGALT00010029875.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017397.1", "url": "https://www.ensembl.org/id/ENSGALP00010017397.1" } ] } }, { "isoform_ac": "A0A8V0YMR2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHY2/entry#A0A8V0YMR2-1", "sequence": { "sequence": "MMCEVMPTINEDTPMSQRGSQSSGSDSDSHFEQLMVNMLDERDRLLDTLRETQESLSLAQQRLQDVIYDRDSLQRQLNSALPQMTVAAGTSIENNIQRTISCPNEFAALTKELNACREQLLEKEEEISELKAERNNTRLLLEHLECLVSRHERSLRMTVVKRQAQSPSGVSSEVEVLKALKSLFEHHKALDEKVRERLRVSLERVSALEEELAAANQEIVALREQNAHIQRKIAAGEGPAESEHIEGVEPGQKVHEKRLSNGSIDSNDETSQVIELQELLEKQNYEMAQMKERMAALSSRVGEVEQEAETARKELIKTEEMNSKYQRDIREAMAQKEDMEERITTLEKRYLSAQRESTSIHDMNDKLENELANKEAILRQLEDKNRQLQERLELAEQKLQQTMRKAETLPEVEAELAQRIAALTKAEERHGNIEERMRHLEAQLEEKNQELQRARQREKMNEEHNKRLSDTVDRLLTESNERLQLHLKERMAALEEKNVLIQESESFRKNLEESLHDKERLAEEIEKLRSELDQMKLRAGSLIEPTLSRPHLDSSAELRYSVGSLVDSQSDYRSTKVIRRPRRGRMGVRRDEPKVKSLGDHEWNRTQQIGVLSSHPFESDTEMSDIDDDDRETLFSSMDLLSPSGHSDAQTLAMMLQEQLDAINKEIRLIQEEKESTELRAEEIENRVASVSLEGLNLARVHQGTSITGSVTASSLASSSPPSGHSTPKLTPRSPAREMDRMGVMTLPSDLRKHRRKIAVVEEDGREDKATIKCETSPPPTPRAIRMTHTLPSSYHNDARSSLPASLEAESIGLGSVSSSQDSLHKAPKKKGIKSSIGRLFGKKEKARLGQLRGYIETEAAAQESLGLGKLGTQAEKDRRLKKNISGHELLEEARRKGLPFAQWDGPTVVAWLELWLGMPAWYVAACRANVKSGAIMSALSDTEIQREIGISNPLHRLKLRLAIQEMVSLTSPSAPPTSRTPSGNVWVTHEEMENLAAPAKTKESEEGSWAQTLAYGDMNHEWIGNEWLPSLGLPQYRSYFMECLVDARMLDHLTKKDLRVHLKMVDSFHRTSLQYGIMCLKRLNYDRKELEKRREMSQHEIKDVLVWSNDRVIRWIQAIGLREYANNILESGVHGSLIALDENFDYSSLALLLQIPTQNTQARQILEREYNNLLALGTERRLEESDDKNFRRGPSWRRQFPPREVHGISMMPGSSETLPAGFRLTTTSGQSRKMATDVASSRLQRLDSSTVRTYSC", "length": 1257, "header": "tr|A0A8V0YMR2-1|A0A8V0YMR2_CHICK Computationally mapped isoform of PTPRF interacting protein alpha 2 OS=Gallus gallus OX=9031 GN=PPFIA2 PE=3 SV=1 CANONICAL=A0A8V0YHY2-1" }, "locus": { "chromosome": "1", "start_pos": 40582347, "end_pos": 40297535, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029903.1", "url": "https://www.ensembl.org/id/ENSGALT00010029903.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017407.1", "url": "https://www.ensembl.org/id/ENSGALP00010017407.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 810, "start_aa": "Thr", "end_pos": 810, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr810", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "R-GGA-181429", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-181429", "resource": "Reactome", "description": "Serotonin Neurotransmitter Release Cycle" }, { "id": "R-GGA-181430", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-181430", "resource": "Reactome", "description": "Norepinephrine Neurotransmitter Release Cycle" }, { "id": "R-GGA-212676", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-212676", "resource": "Reactome", "description": "Dopamine Neurotransmitter Release Cycle" }, { "id": "R-GGA-264642", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-264642", "resource": "Reactome", "description": "Acetylcholine Neurotransmitter Release Cycle" }, { "id": "R-GGA-388844", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-388844", "resource": "Reactome", "description": "Receptor-type tyrosine-protein phosphatases" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHY2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHY2" } ], "pmid": "" }, { "name": "axon", "id": "GO:0030424", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030424", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHY2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHY2" } ], "pmid": "" }, { "name": "dendritic spine", "id": "GO:0043197", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043197", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHY2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHY2" } ], "pmid": "" }, { "name": "presynaptic active zone", "id": "GO:0048786", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048786", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHY2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHY2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "synapse organization", "id": "GO:0050808", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050808", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHY2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHY2" } ], "pmid": "" }, { "name": "regulation of dendritic spine development", "id": "GO:0060998", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060998", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHY2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHY2" } ], "pmid": "" }, { "name": "regulation of dendritic spine morphogenesis", "id": "GO:0061001", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061001", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHY2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHY2" } ], "pmid": "" }, { "name": "dense core granule cytoskeletal transport", "id": "GO:0099519", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099519", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHY2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHY2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 135, "end_pos": 137, "annotation": "n_glycosylation_sequon" }, { "start_pos": 261, "end_pos": 263, "annotation": "n_glycosylation_sequon" }, { "start_pos": 633, "end_pos": 635, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YHY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHY2" }, { "id": "PS50105", "database": "PROSITE", "url": 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"relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YHY6-1", "uniprot_ac": "A0A8V0YHY6", "uniprot_id": "A0A8V0YHY6_CHICK", "mass": { "chemical_mass": 18660.0, "monoisotopic_mass": 18660.0 }, "refseq": {}, "gene_names": [ { "name": "FAM162B", "type": "recommended", "evidence": [ { "id": "A0A8V0YHY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHY6" } ] } ], "protein_names": [ { "name": "Family with sequence similarity 162 member B", "type": "synonym", "evidence": [ { "id": "A0A8V0YHY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHY6/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { 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"id": "gga:100857953", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100857953", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "KGRGEVH", "url": "https://omabrowser.org/oma/group/KGRGEVH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR13674", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13674", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13674:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13674:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF06388", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06388", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YHY6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHY6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHY6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHY6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YR40", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YR40", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YR40-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YR40-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLPKGGGSEGCTEGEAPPSLEELKARLDEALGSLSWALRGICSFHHYCHSSQQPDGVFLSKPSAEQAHKVVASYKPSKFDKKILLWTGRFKTEEEIPPRIPPEMLDRARNKARVKACYIMIGLSIVACFAVIASAKKAAARHESLTSWNLAKKEKWRKEAALVAESKPK", "length": 169, "header": "tr|A0A8V0YHY6-1|A0A8V0YHY6_CHICK Isoform 1 of Family with sequence similarity 162 member B OS=Gallus gallus OX=9031 GN=FAM162B PE=3 SV=1 CANONICAL=A0A8V0YHY6-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YHY6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHY6/entry#A0A8V0YHY6-1", "sequence": { "sequence": "MLPKGGGSEGCTEGEAPPSLEELKARLDEALGSLSWALRGICSFHHYCHSSQQPDGVFLSKPSAEQAHKVVASYKPSKFDKKILLWTGRFKTEEEIPPRIPPEMLDRARNKARVKACYIMIGLSIVACFAVIASAKKAAARHESLTSWNLAKKEKWRKEAALVAESKPK", "length": 169, "header": "tr|A0A8V0YHY6-1|A0A8V0YHY6_CHICK Isoform 1 of Family with sequence similarity 162 member B OS=Gallus gallus OX=9031 GN=FAM162B PE=3 SV=1 CANONICAL=A0A8V0YHY6-1" }, "locus": { "chromosome": "3", "start_pos": 63455884, "end_pos": 63453263, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010035152.1", "url": "https://www.ensembl.org/id/ENSGALT00010035152.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020502.1", "url": "https://www.ensembl.org/id/ENSGALP00010020502.1" } ] } }, { "isoform_ac": "A0A8V0YR40-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHY6/entry#A0A8V0YR40-1", "sequence": { "sequence": "MLSLPLRLRPGRVRGAPLLHPAALRRAAAGDGPGRGPAVPRAEQAHKVVASYKPSKFDKKILLWTGRFKTEEEIPPRIPPEMLDRARNKARVKACYIMIGLSIVACFAVIASAKKAAARHESLTSWNLAKKEKWRKEAALVAESKPK", "length": 147, "header": "tr|A0A8V0YR40-1|A0A8V0YR40_CHICK Computationally mapped isoform of Family with sequence similarity 162 member B OS=Gallus gallus OX=9031 GN=FAM162B PE=3 SV=1 CANONICAL=A0A8V0YHY6-1" }, "locus": { "chromosome": "3", "start_pos": 63455884, "end_pos": 63453009, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010035161.1", "url": "https://www.ensembl.org/id/ENSGALT00010035161.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020505.1", "url": "https://www.ensembl.org/id/ENSGALP00010020505.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:100857953", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100857953", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A6QPI4-1", "protein_name": "Protein FAM162B", "gene_name": "FAM162B", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MLATVGSLLRLRLGRIPCCAPGAPPEVERRPVASLWPRGHPQYSCGGSPGSSEPPGSAEKVHRVPAEHKPSQFDKRILLWTGRFKAMEDIPPRIPPEMIDAARNKARVKACYIMIGLTIIACFAVIASAKRAAERHESLTSWNLAKKAKWREEAALAAQAKAK", "length": 163 }, "evidence": [ { "id": "A0A8V0YHY6", "url": "https://omabrowser.org/oma/group/A0A8V0YHY6/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q5T6X4-1", "protein_name": "Protein FAM162B", "gene_name": "FAM162B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLRAVGSLLRLGRGLTVRCGPGAPLEATRRPAPALPPRGLPCYSSGGAPSNSGPQGHGEIHRVPTQRRPSQFDKKILLWTGRFKSMEEIPPRIPPEMIDTARNKARVKACYIMIGLTIIACFAVIVSAKRAVERHESLTSWNLAKKAKWREEAALAAQAKAK", "length": 162 }, "evidence": [ { "id": "A0A8V0YHY6", "url": "https://omabrowser.org/oma/group/A0A8V0YHY6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9CX19-1", "protein_name": "Protein FAM162B", "gene_name": "Fam162b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLWVSRSVLRLGLGFTTHRAPQIISRWPRWGPRVACHPCSSSGQNPSGFEPPEKVHRIPAQYKPSKFDKKILLWTGRFKSIEDIPPLVPPEMIAVSRNKARVKACYIMIGLTIVACFAVIVSAKRAVERHESLTSWNLAKKAKWREEAALAAQSKSK", "length": 157 }, "evidence": [ { "id": "A0A8V0YHY6", "url": "https://omabrowser.org/oma/group/A0A8V0YHY6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHY6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHY6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YI12-1", "uniprot_ac": "A0A8V0YI12", "uniprot_id": "A0A8V0YI12_CHICK", "mass": { "chemical_mass": 95622.0, "monoisotopic_mass": 95622.0 }, "refseq": { "ac": "XP_025009973", "name": "TBC1 domain family member 30 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025009973" }, "gene_names": [ { "name": "TBC1D30", "type": "recommended", "evidence": [ { "id": "A0A8V0YI12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI12" } ] }, { "name": "TBC1D30", "type": "synonym", "evidence": [ { "id": "XP_025009973", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025009973" } ] } ], "protein_names": [ { "name": "TBC1 domain family member 30", "type": "recommended", "evidence": [ { "id": "A0A8V0YI12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI12/entry#names_and_taxonomy" } ] }, { "name": "TBC1 domain family member 30 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_025009973", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025009973" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_025009973.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_025009973", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025009973" } ] }, { "annotation": "May act as a GTPase-activating protein for Rab family protein(s).", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCF3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCF3#function" }, { "database": "UniProtKB", "id": "ARBA00043879", "url": "https://www.uniprot.org/uniprotkb/ARBA00043879#function" }, { "database": "UniProtKB", "id": "A0A8V0YHY8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHY8#function" }, { "database": "UniProtKB", "id": "A0A8V0YKU1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKU1#function" }, { "database": "UniProtKB", "id": "A0A8V0YI12", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI12#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YI12", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI12" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TBC1D30", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI12", "locus": { "chromosome": "1", "start_pos": 33971454, "end_pos": 33921523, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013179", "url": "https://www.ensembl.org/id/ENSGALG00010013179" } ] } } ], "crossref": [ { "id": "A0A8V0YI12", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YI12", "database": "AlphaFoldDB", "categories": [] }, { "id": "417830", "url": "https://www.ncbi.nlm.nih.gov/gene/417830", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000195", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000195", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032738", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032738", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035969", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035969", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "WAKLGXT", "url": "https://omabrowser.org/oma/group/WAKLGXT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YCF3", "url": "https://www.orthodb.org/?gene=A0A8V0YCF3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YHY8", "url": "https://www.orthodb.org/?gene=A0A8V0YHY8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YI12", "url": "https://www.orthodb.org/?gene=A0A8V0YI12", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YKU1", "url": "https://www.orthodb.org/?gene=A0A8V0YKU1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13399", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13399", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13399:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13399:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00566", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00566", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF15733", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15733", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_025009973", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025009973", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YCF3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCF3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YCF3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCF3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHY8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHY8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHY8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHY8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YI12", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI12", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YI12-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI12-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YKU1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKU1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YKU1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKU1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEAGERGAGGRAGSSADSLAEEEDEEDEEVPGSGRSSRTSSLVSGLLTELYSAAEVAAPPRVLRELQQQRPSRAEYLRLKDVDELTTIKRELNYRISVQSAKLLHLLKLKDRLVHKVQKNCDIVTACLQAVSQKRRVDTKLKFTLEPSLGQNGFQQWHDALKAVARLPTGIPKEWRRKVWLTLADQYLHSIAIDWDKTMRFTFNERSNPDDDSMGIQIVKDLHRTGCSSYCGQEAEQDRVVLKRVLLAYARWNKSVGYCQGFNILAALILEVMEGNEGDALKIMIYLIDKVLPDSYFVNNLRALSVDMAVFRDLLRMNLPELSQHLDTLQRAANRESGGGYEPPLTNVFTMQWFLTLFATCLPNHTVLKIWDSVFFEGSEIILRVALAIWAKLGEQIECCETADEFYSTMGKLTQEMLEDSLIDSNELMQTVYTMAQFPFPQLAELREKYTYNITPFPATVKSTSLSGRLGRTRDSDEENDLDDEDSIANAIGCLGPLSGFLAPELQKYQKQMKDQNEEQSLGSSNIAELSPGAIDSCRSEYHAAFNSMMMERMTTDINALKKQYSRIKKKQQQQVHHVYIRAGSEDDDPGIFLGPRNQLNNDKGPVTSILPSQVNHSPVINHLLLGKKLKSSNKSLKNAVIHIPSHATGKMSPIPQEDLKSKLNSPWRTHIRVHRKNIARAKGQLGYGDTIGLIDEQSESCKTNCPGAKEDASKHSDFGEGGGSLDDRTTRKADQQSADAVSMDSNTDMTVVQLKLETLELTSDNKTDAESTSSQSRLSEPSSSSSDNGNLAKSPQSGNSKPQVFNPFPSVKPLRKSATARNLGLYGPTERTPTVHFPQMSRSFSKSASANSGTRKR", "length": 858, "header": "tr|A0A8V0YI12-1|A0A8V0YI12_CHICK Isoform 1 of TBC1 domain family member 30 OS=Gallus gallus OX=9031 GN=TBC1D30 PE=4 SV=1 CANONICAL=A0A8V0YI12-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YCF3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI12/entry#A0A8V0YCF3-1", "sequence": { "sequence": "MRFTFNERSNPDDDSMGIQIVKDLHRTGCSSYCGQEAEQDRVVLKRVLLAYARWNKSVGYCQGFNILAALILEVMEGNEGDALKIMIYLIDKVLPDSYFVNNLRALSVDMAVFRDLLRMNLPELSQHLDTLQRAANRESGGGYEPPLTNVFTMQWFLTLFATCLPNHTVLKIWDSVFFEGSEIILRVALAIWAKLGEQIECCETADEFYSTMGKLTQEMLEDSLIDSNELMQTVYTMAQFPFPQLAELREKYTYNITPFPATVKSTSLSGRLGRTRDSDEENDLDDEDSIANAIGCLGPLSGFLAPELQKYQKQMKDQNEEQSLGSSNIAELSPGAIDSCRSEYHAAFNSMMMERMTTDINALKKQYSRIKKKQQQQVHHVYIRADKGPVTSILPSQVNHSPVINHLLLGKKLKSSNKSLKNAVIHIPSHATGKMSPIPQEDLKSKLNSPWRTHIRVHRKNIARAKGQLGYGDTIGLIDEQSESCKTNCPGAKEDASKHSDFGEGGGSLDDRTTRKADQQSADAVSMDSNTDMTVVQLKLETLELTSDNKTDAESTSSQSRLSEPSSSSSDNGNLAKSPQSGNSKPQVFNPFPSVKPLRKSATARNLGLYGPTERTPTVHFPQMSRSFSKSASANSGTRKR", "length": 641, "header": "tr|A0A8V0YCF3-1|A0A8V0YCF3_CHICK Computationally mapped isoform of TBC1 domain family member 30 OS=Gallus gallus OX=9031 GN=TBC1D30 PE=4 SV=1 CANONICAL=A0A8V0YI12-1" }, "locus": { "chromosome": "1", "start_pos": 33969419, "end_pos": 33949538, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031613.1", "url": "https://www.ensembl.org/id/ENSGALT00010031613.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018480.1", "url": "https://www.ensembl.org/id/ENSGALP00010018480.1" } ] } }, { "isoform_ac": "A0A8V0YHY8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI12/entry#A0A8V0YHY8-1", "sequence": { "sequence": "MRQERLTGSLRRGGRCLKRQSSGGGVGTILSNVLKKRSCISRTAPRLLCTLEPGVDTKLKFTLEPSLGQNGFQQWHDALKAVARLPTGIPKEWRRKVWLTLADQYLHSIAIDWDKTMRFTFNERSNPDDDSMGIQIVKDLHRTGCSSYCGQEAEQDRVVLKRVLLAYARWNKSVGYCQGFNILAALILEVMEGNEGDALKIMIYLIDKVLPDSYFVNNLRALSVDMAVFRDLLRMNLPELSQHLDTLQRAANRESGGGYEPPLTNVFTMQWFLTLFATCLPNHTVLKIWDSVFFEGSEIILRVALAIWAKLGEQIECCETADEFYSTMGKLTQEMLEDSLIDSNELMQTVYTMAQFPFPQLAELREKYTYNITPFPATVKSTSLSGRLGRTRDSDEENDLDDEDSIANAIGCLGPLSGFLAPELQKYQKQMKDQNEEQSLGSSNIAELSPGAIDSCRSEYHAAFNSMMMERMTTDINALKKQYSRIKKKQQQQVHHVYIRADKGPVTSILPSQVNHSPVINHLLLGKKLKSSNKSLKNAVIHIPSHATGKMSPIPQEDLKSKLNSPWRTHIRVHRKNIARAKGQLGYGDTIGLIDEQSESCKTNCPGAKEDASKHSDFGEGGGSLDDRTTRKADQQSADAVSMDSNTDMTVVQLKLETLELTSDNKTDAESTSSQSRLSEPSSSSSDNGNLAKSPQSGNSKPQVFNPFPSVKPLRKSATARNLGLYGPTERTPTVHFPQMSRSFSKSASANSGTRKR", "length": 757, "header": "tr|A0A8V0YHY8-1|A0A8V0YI12_CHICK Computationally mapped isoform of TBC1 domain family member 30 OS=Gallus gallus OX=9031 GN=TBC1D30 PE=4 SV=1 CANONICAL=A0A8V0YI12-1" }, "locus": { "chromosome": "1", "start_pos": 33969419, "end_pos": 33941281, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031607.1", "url": "https://www.ensembl.org/id/ENSGALT00010031607.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018474.1", "url": "https://www.ensembl.org/id/ENSGALP00010018474.1" } ] } }, { "isoform_ac": "A0A8V0YI12-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI12/entry#A0A8V0YI12-1", "sequence": { "sequence": "MEAGERGAGGRAGSSADSLAEEEDEEDEEVPGSGRSSRTSSLVSGLLTELYSAAEVAAPPRVLRELQQQRPSRAEYLRLKDVDELTTIKRELNYRISVQSAKLLHLLKLKDRLVHKVQKNCDIVTACLQAVSQKRRVDTKLKFTLEPSLGQNGFQQWHDALKAVARLPTGIPKEWRRKVWLTLADQYLHSIAIDWDKTMRFTFNERSNPDDDSMGIQIVKDLHRTGCSSYCGQEAEQDRVVLKRVLLAYARWNKSVGYCQGFNILAALILEVMEGNEGDALKIMIYLIDKVLPDSYFVNNLRALSVDMAVFRDLLRMNLPELSQHLDTLQRAANRESGGGYEPPLTNVFTMQWFLTLFATCLPNHTVLKIWDSVFFEGSEIILRVALAIWAKLGEQIECCETADEFYSTMGKLTQEMLEDSLIDSNELMQTVYTMAQFPFPQLAELREKYTYNITPFPATVKSTSLSGRLGRTRDSDEENDLDDEDSIANAIGCLGPLSGFLAPELQKYQKQMKDQNEEQSLGSSNIAELSPGAIDSCRSEYHAAFNSMMMERMTTDINALKKQYSRIKKKQQQQVHHVYIRAGSEDDDPGIFLGPRNQLNNDKGPVTSILPSQVNHSPVINHLLLGKKLKSSNKSLKNAVIHIPSHATGKMSPIPQEDLKSKLNSPWRTHIRVHRKNIARAKGQLGYGDTIGLIDEQSESCKTNCPGAKEDASKHSDFGEGGGSLDDRTTRKADQQSADAVSMDSNTDMTVVQLKLETLELTSDNKTDAESTSSQSRLSEPSSSSSDNGNLAKSPQSGNSKPQVFNPFPSVKPLRKSATARNLGLYGPTERTPTVHFPQMSRSFSKSASANSGTRKR", "length": 858, "header": "tr|A0A8V0YI12-1|A0A8V0YI12_CHICK Isoform 1 of TBC1 domain family member 30 OS=Gallus gallus OX=9031 GN=TBC1D30 PE=4 SV=1 CANONICAL=A0A8V0YI12-1" }, "locus": { "chromosome": "1", "start_pos": 33969419, "end_pos": 33921544, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031629.1", "url": "https://www.ensembl.org/id/ENSGALT00010031629.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018494.1", "url": "https://www.ensembl.org/id/ENSGALP00010018494.1" } ] } }, { "isoform_ac": "A0A8V0YKU1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI12/entry#A0A8V0YKU1-1", "sequence": { "sequence": "MEAGERGAGGRAGSSADSLAEEEDEEDEEVPGSGRSSRTSSLVSGLLTELYSAAEVAAPPRVLRELQQQRPSRAEYLRLKDVDELTTIKRELNYRISVQSAKLLHLLKLKDRLVHKVQKNCDIVTACLQAVSQKRRVDTKLKFTLEPSLGQNGFQQWHDALKAVARLPTGIPKEWRRKVWLTLADQYLHSIAIDWDKTMRFTFNERSNPDDDSMGIQIVKDLHRTGCSSYCGQEAEQDRVVLKRVLLAYARWNKSVGYCQGFNILAALILEVMEGNEGDALKIMIYLIDKVLPDSYFVNNLRALSVDMAVFRDLLRMNLPELSQHLDTLQRAANRESGGGYEPPLTNVFTMQWFLTLFATCLPNHTVLKIWDSVFFEGSEIILRVALAIWAKLGEQIECCETADEFYSTMGKLTQEMLEDSLIDSNELMQTVYTMAQFPFPQLAELREKYTYNITPFPATVKSTSLSGRLGRTRDSDEENDLDDEDSIANAIGCLGPLSGFLAPELQKYQKQMKDQNEEQSLGSSNIAELSPGAIDSCRSEYHAAFNSMMMERMTTDINALKKQYSRIKKKQQQQVHHVYIRADKGPVTSILPSQVNHSPVINHLLLGKKLKSSNKSLKNAVIHIPSHATGKMSPIPQEDLKSKLNSPWRTHIRVHRKNIARAKGQLGYGDTIGLIDEQSESCKTNCPGAKEDASKHSDFGEGGGSLDDRTTRKADQQSADAVSMDSNTDMTVVQLKLETLELTSDNKTDAESTSSQSRLSEPSSSSSDNGNLAKSPQSGNSKPQVFNPFPSVKPLRKSATARNLGLYGPTERTPTVHFPQMSRSFSKSASANSGTRKR", "length": 839, "header": "tr|A0A8V0YKU1-1|A0A8V0YKU1_CHICK Computationally mapped isoform of TBC1 domain family member 30 OS=Gallus gallus OX=9031 GN=TBC1D30 PE=4 SV=1 CANONICAL=A0A8V0YI12-1" }, "locus": { "chromosome": "1", "start_pos": 33969419, "end_pos": 33921544, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031622.1", "url": "https://www.ensembl.org/id/ENSGALT00010031622.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018488.1", "url": "https://www.ensembl.org/id/ENSGALP00010018488.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A3Q1N272-1", "protein_name": "TBC1 domain family member 30", "gene_name": "TBC1D30", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MRQDKLTGSLRRGGRCLKRQGGGGGGGGGVGTILSNVLKKRSCISRTAPRLLCTLEPGVDTKLKFTLEPSLGQNGFQQWYDALKAVARLSTGIPKEWRRKVWLTLADHYLHSIAIDWDKTMRFTFNERSNPDDDSMGIQIVKDLHRTGCSSYCGQEAEQDRVVLKRVLLAYARWNKNVGYCQGFNILAALILEVVEGNEGDALKIMIYLIDKVLPESYFVNNLRALSVDMAVFRDLLRLNLPELSQHLDTLQKTANKESGGGYEPPLTNVFTMQWFLTLFATCLPNHTVLKIWDSVFFEGSEIILRVSLAIWAKLGEQIECCETADEFYSTMGRLTQEMLENDLLESHELMQTVYSMAPFPFPQLAELREKYTYNITPFPATVKPTSISGRHGKVRDSDEENDPDDEDVIANAVGCLGPFSGLLAPELQKYQKQVKESNGDQSLRSNNIAELSPGAINSCRSEYHAASNSMMMERMTTDINALKRQYSRIKKKQQQQVHQVYIRADKGPVTSILPSQVNSSPVINHLLLGKKMKMSNRAAKNAVIHIPGHTGGKISPVPYEDLRTKLNSPWRTHIRVHKKNMARTKSQLGCGDMVGLIEEQSEGSKTHTLGAAKASPSDCVGTAQGGCSDGSTGRTIEGRSPEPVFGDGDADVSEVQVKIEALELTPRDAAAEPEPRVPPPSQRHFPEPPNAPGGNRVPGKAPQGGSHPKTPIFSPFPSVKPLRKSTAARNLGLYGPTERTPTVHFPHMSRSFSKSGSGNSSTKKR", "length": 766 }, "evidence": [ { "id": "A0A8V0YI12", "url": "https://omabrowser.org/oma/group/A0A8V0YI12/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "I3LBK2-1", "protein_name": "TBC1 domain family member 30", "gene_name": "TBC1D30", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRQDKLTGSLRRGGRCLKRQGGGGGGGGGGVGTILSNVLKKRSCISRTAPRLLCTLEPGVDTKLKFTLEPSLGQNGFQQWYDALKAVARLSTGIPKEWRRKVWLTLADHYLHSIAIDWDKTMRFTFNERSNPDDDSMGIQIVKDLHRTGCSSYCGQEAEQDRVVLKRVLLAYARWNKNVGYCQGFNILAALILEVVEGNEGDALKIMIYLIDKVLPESYFVNNLRALSVDMAVFRDLLRLKLPELSQHLDTLQRTANKESGGGYEPPLTNVFTMQWFLTLFATCLPNQTVLKIWDSVFFEGSEIILRVSLAIWAKLGEQIECCETADEFYSTMGRLTQEMLENDLLESHELMQTVYSMAPFPFPQLAELREKYTYNITPFPAAVKPTSVSGRHSKVRDSDEENDPDDEDAIANAVGCLGPFSGLLAPELQKYQKQIKEPNGDQSLRANNIAELSPGAINSCRSEYHAAFNSMMMERMTTDINALKRQYSRIKKKQQQQAHQVYIRADKGPVTSILPSQVNNSPVINHLLLGKKMKLSNRAAKNAVIHIPGHTGGKVSPVPYEDLRAKLNSPWRTHIRVHKKNMTRTRSQLGCGDTIGLIEEQNDGKTHNPGAAEAFASSCSVTAGREGGGSDGGSGRTPQEQSPEPGLGEADADVSDVQVKLEALELNPRDAAAETEPKGHLPCLRPFPGPPDTPGGSKATGKSPPGSHPKAPIFSPFPSVKPLRKSATARNLGLYGPTERTPTVHFPRMSRSFSKSSGGNSGTKKR", "length": 767 }, "evidence": [ { "id": "A0A8V0YI12", "url": "https://omabrowser.org/oma/group/A0A8V0YI12/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q9Y2I9-1", "protein_name": "TBC1 domain family member 30", "gene_name": "TBC1D30", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDVLPTGGGRPGLRTELEFRGGGGEARLESQEEETIPAAPPAPRLRGAAERPRRSRDTWDGDEDTEPGEACGGRTSRTASLVSGLLNELYSCTEEEEAAGGGRGAEGRRRRRDSLDSSTEASGSDVVLGGRSGAGDSRVLQELQERPSQRHQMLYLRQKDANELKTILRELKYRIGIQSAKLLRHLKQKDRLLHKVQRNCDIVTACLQAVSQKRRVDTKLKFTLEPSLGQNGFQQWYDALKAVARLSTGIPKEWRRKVWLTLADHYLHSIAIDWDKTMRFTFNERSNPDDDSMGIQIVKDLHRTGCSSYCGQEAEQDRVVLKRVLLAYARWNKTVGYCQGFNILAALILEVMEGNEGDALKIMIYLIDKVLPESYFVNNLRALSVDMAVFRDLLRMKLPELSQHLDTLQRTANKESGGGYEPPLTNVFTMQWFLTLFATCLPNQTVLKIWDSVFFEGSEIILRVSLAIWAKLGEQIECCETADEFYSTMGRLTQEMLENDLLQSHELMQTVYSMAPFPFPQLAELREKYTYNITPFPATVKPTSVSGRHSKARDSDEENDPDDEDAVVNAVGCLGPFSGFLAPELQKYQKQIKEPNEEQSLRSNNIAELSPGAINSCRSEYHAAFNSMMMERMTTDINALKRQYSRIKKKQQQQVHQVYIRADKGPVTSILPSQVNSSPVINHLLLGKKMKMTNRAAKNAVIHIPGHTGGKISPVPYEDLKTKLNSPWRTHIRVHKKNMPRTKSHPGCGDTVGLIDEQNEASKTNGLGAAEAFPSGCTATAGREGSSPEGSTRRTIEGQSPEPVFGDADVDVSAVQAKLGALELNQRDAAAETELRVHPPCQRHCPEPPSAPEENKATSKAPQGSNSKTPIFSPFPSVKPLRKSATARNLGLYGPTERTPTVHFPQMSRSFSKPGGGNSGTKKR", "length": 924 }, "evidence": [ { "id": "A0A8V0YI12", "url": "https://omabrowser.org/oma/group/A0A8V0YI12/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "negative regulation of cilium assembly", "id": "GO:1902018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902018", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YI12", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI12" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YI12", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI12" } ], "pmid": "" }, { "name": "small GTPase binding", "id": "GO:0031267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031267", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YI12", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI12" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YI12", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI12" } ], "pmid": "" }, { "name": "ciliary basal body", "id": "GO:0036064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036064", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YI12", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI12" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 253, "end_pos": 255, "annotation": "n_glycosylation_sequon" }, { "start_pos": 364, "end_pos": 366, "annotation": "n_glycosylation_sequon" }, { "start_pos": 453, "end_pos": 455, "annotation": "n_glycosylation_sequon" }, { "start_pos": 616, "end_pos": 618, "annotation": "n_glycosylation_sequon" }, { "start_pos": 634, "end_pos": 636, "annotation": "n_glycosylation_sequon" }, { "start_pos": 766, "end_pos": 768, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YI12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI12" }, { "id": "PS50086", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50086" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Rab-GAP TBC", "eco_id": "ECO_0000259", "start_pos": 170, "end_pos": 378, "start_aa": "Gly", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 253, "end_pos": 255 }, { "start_pos": 364, "end_pos": 366 }, { "start_pos": 453, "end_pos": 455 }, { "start_pos": 616, "end_pos": 618 }, { "start_pos": 634, "end_pos": 636 }, { "start_pos": 766, "end_pos": 768 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YI06-1", "uniprot_ac": "A0A8V0YI06", "uniprot_id": "A0A8V0YI06_CHICK", "mass": { "chemical_mass": 236624.0, "monoisotopic_mass": 236624.0 }, "refseq": { "ac": "XP_015133927", "name": "dedicator of cytokinesis protein 11 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015133927" }, "gene_names": [ { "name": "DOCK11", "type": "recommended", "evidence": [ { "id": "A0A8V0YI06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI06" } ] }, { "name": "DOCK11", "type": "synonym", "evidence": [ { "id": "XP_015133927", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015133927" } ] } ], "protein_names": [ { "name": "Dedicator of cytokinesis 11", "type": "synonym", "evidence": [ { "id": "A0A8V0YI06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI06/entry#names_and_taxonomy" } ] }, { "name": "dedicator of cytokinesis protein 11 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015133927", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015133927" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052535.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015133927.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015133927", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015133927" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YI06", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI06" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "DOCK11", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI06", "locus": { "chromosome": "4", "start_pos": 3342293, "end_pos": 3272712, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010014641", "url": "https://www.ensembl.org/id/ENSGALG00010014641" } ] } } ], "crossref": [ { "id": "cd08697", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd08697", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd11700", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11700", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd13267", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13267", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "422229", "url": "https://www.ncbi.nlm.nih.gov/gene/422229", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001849", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001849", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR021816", "url": "https://www.ebi.ac.uk/interpro/entry/IPR021816", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR026791", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026791", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027007", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027007", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027357", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027357", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035892", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035892", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037809", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037809", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043161", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043161", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043162", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043162", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046769", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046769", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046770", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046770", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046773", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046773", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:422229", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422229", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "IAVCMEF", "url": "https://omabrowser.org/oma/group/IAVCMEF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YHZ1", "url": "https://www.orthodb.org/?gene=A0A8V0YHZ1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YI06", "url": "https://www.orthodb.org/?gene=A0A8V0YI06", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23317", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23317", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23317:SF81", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23317:SF81", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00169", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00169", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF06920", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06920", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF11878", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11878", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14429", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14429", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF20421", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF20421", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF20422", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF20422", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF28208", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF28208", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-9013148", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013148", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9013149", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013149", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-983231", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983231", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_015133927", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015133927", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YHZ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHZ1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHZ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHZ1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YI06", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI06", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YI06-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI06-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSEVRKFTKRLSKPGTAAELRQSVSEAVRSSFALEKTKVVEPLDYENVILQRKVQIYSDPLRDLLIFPIEDVSLSVISRQRRTVQSTVPEDALKKAQSLFVKECIKTYSSDWHVVNYKYEEYSGDFRMLPCKSFRPDKIPSHVFEIDEDFEKDEDSSSLCSQKGGVIKQGWLHKANVNSTITVTMRVFKRRYFYLSQLTDGSYILNSYKDEKISKESKGCIFLDACNDVVQCPKMRRYAFELKTIDKYSHYLAAESEQEMEEWLVTLRKIIQSNTESSVQEKKDTVEAAQDDESSTQGKSENILESLERSMHPELMKYGRETDQLNKLSRNDGRQNLFSFDPEVQRLDFSGMEPDVKPFEEKSSRRFVVCCQDLSLNLLAQLSDQSEGGPTNVEPFFLSLALFDLKNNCKISADFHVDLNPPPVRDMLLDTSASKVEDVKGRSPGESLMHGIPESCLRYIKRGVFSVTDPHAEIFLVARVEKVLQGSITHCAEPYMKNSDPGKTAQKVHKVAKQVCSRLGLYRMPFGWAARPVFKDSQGTLDAEGKFSPLYKQDSGKLSNEDMLKLLAEYKKPEKTKLQIIPAQLNIVIKDIPLDFTNCVTASYIPIKPFEKSCENIAVEVEELVPEVAKYCYPFTVYKNHLYVYPLHLKYENQKVFAKARNIAVCIEFRDSDEADARPLKCIYGKPGGQLLTSNAYAAVLHHNQSPEFYDEIKIELPIHLHQKHHLLFTFYHVSCEINTKATSKKQDTVETQVGYAWVPLLKDGRIVTLERHLPVSSNLPPGYLGLGDTESRRQSSVDAKWVDGAKPLFKIRIHLDSTIYTQDMHLHKFFQYCQLVQAGVKEVPGELVKYLKCLHAMETQVMIQFLPVILMQLFRVLTNVTQEDEVAVNCTMVLLHIVSKCHEEGLDHYLRSFIKYVFRAEKPSVTQAKMTHEILVLSMATILKQSADFLAINKLLKYSWFFFEALAKSMAIYLLEENKIKLPRAQRFPDSYQHALHSLLLAIIPHVTIRYNEIPEESRNANFSLANFLKRCLTFMDRGFVFNLINDYISGFSPKDPKLLVEYKFEFLQTICNHEHYIPLNLPMTFSKPKLQRAQDVNLEYSLTDEYCRHHFLVGMLLRETSVALQDNYDIRCTAITVLKNLLIKHAFDNRYQHKNQQAKIVQLYLPLLGLLLENIQRVAGRDVLISCTAASSPASRDEFICNFASPSNRSSLIADKDSAALPNGHGMKREDSKGSLNSEGATGSPDQSENIRRSSTRSSVSHCSRLDQFEIRTLLMCYLYIVKMISEDTLLAYWNKFSPQELINVLVLLEVCLFHFRYVGKRNIARVHDAWVSKHGAADRKSQTMPALRSRAGGMQARLQHLGSLDTSFTLNHNAGTSEADIVHQALLEGNIATEVCLTVLDTISFFTQSFKTQLLSNDGHNPLMKKVFDIHLAFLKNGQSEAALKHVFASLRAFISKFPSAFFKGRVNMCAALCYEILKCCTSKVTSTRNEASALLYLLMRNNFEFTKRRTFLRTHLQIIIAVSQLIADVALSGGTRFQDSLLIINNFANSDRPMKATAFPSEVKDLTKRIRTVLMATAQMKEHEKDPEMLIDLQYSLAKSYASTPELRKTWLDSMAKIHVKNGDFSEAAMCYVHVAALVAEFLHRKKLFPSGCTAFRKITPNIDEEGAMKEDGGMMDVHYSEEVLVELLEQCVDGLWKAERYETISEVSKLIIPIYEKRREFEKLTQLYRTLHGAYAKILEVMHTRKRLLGTFFRVAFYGQTFFEEEDGKEYIYKEPKLTGLSEISFRLLKLYGEKFGSETVKIIQDSNKVNIKDLDPRYAHIQVTYVKPYFEDKEISERKTEFERNHNINRFVFETPYTLSGKKHGSVEEQCKKRTILTTLNSFPYVKKRIPVNYEHQVNLKPIDVATDEIKDKTAELQKLCSASDVDMIQLQLKLQGCVSVQVNAGPLAYARAFLSDSQSSKYPAKKVNELKEMFRKFIQACGIALELNERLIKEDQVEYHEGLKSNFRDMVKELSDIIHEQIYHEDPMHSPWMHDSLHVFCAISGTSSNGSYCSLRPTAEI", "length": 2068, "header": "tr|A0A8V0YI06-1|A0A8V0YI06_CHICK Isoform 1 of Dedicator of cytokinesis 11 OS=Gallus gallus OX=9031 GN=DOCK11 PE=3 SV=1 CANONICAL=A0A8V0YI06-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YHZ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI06/entry#A0A8V0YHZ1-1", "sequence": { "sequence": "MSEVRKFTKRLSKPGTAAELRQSVSEAVRSSFALEKTKVVEPLDYENVILQRKVQIYSDPLRDLLIFPIEDVSLSVISRQRRTVQSTVPEDALKKAQSLFVKECIKTYSSDWHVVNYKYEEYSGDFRMLPCKSFRPDKIPSHVFEIDEDFEKDEDSSSLCSQKGGVIKQGWLHKANVNSTITVTMRVFKRRYFYLSQLTDGSYILNSYKDEKISKESKGCIFLDACNDVVQCPKMRRYAFELKTIDKYSHYLAAESEQEMEEWLVTLRKIIQSNTESSVQEKKDTVEAAQDDESSTQGKSENILESLERSMHPELMKYGRETDQLNKLSRNDGRQNLFSFDPEVQRLDFSGMEPDVKPFEEKSSRRFVVCCQDLSLNLLAQLSDQSEGGPTNVEPFFLSLALFDLKNNCKISADFHVDLNPPPVRDMLLDTSASKVEDVKGRSPGESLMHGIPESCLRYIKRGVFSVTDPHAEIFLVARVEKVLQGSITHCAEPYMKNSDPGKTAQKVHKVAKQVCSRLGLYRMPFGWAARPVFKDSQGTLDAEGKFSPLYKQDSGKLSNEDMLKLLAEYKKPEKTKLQIIPAQLNIVIKDIPLDFTNCVTASYIPIKPFEKSCENIAVEVEELVPEVAKYCYPFTVYKNHLYVYPLHLKYENQKVFAKARNIAVCIEFRDSDEADARPLKCIYGKPGGQLLTSNAYAAVLHHNQSPEFYDEIKIELPIHLHQKHHLLFTFYHVSCEINTKATSKKQDTVETQVGYAWVPLLKDGRIVTLERHLPVSSNLPPGYLGLGDTESRRQSSVDAKWVDGAKPLFKIRIHLDSTIYTQDMHLHKFFQYCQLVQAGVKEVPGELVKYLKCLHAMETQVMIQFLPVILMQLFRVLTNVTQEDEVAVNCTMVLLHIVSKCHEEGLDHYLRSFIKYVFRAEKPSVTQAKMTHEILVLSMATILKQSADFLAINKLLKYSWFFFEALAKSMAIYLLEENKIKLPRAQRFPDSYQHALHSLLLAIIPHVTIRYNEIPEESRNANFSLANFLKRCLTFMDRGFVFNLINDYISGFSPKDPKLLVEYKFEFLQTICNHEHYIPLNLPMTFSKPKLQRAQDVNLEYSLTDEYCRHHFLVGMLLRETSVALQDNYDIRCTAITVLKNLLIKHAFDNRYQHKNQQAKIVQLYLPLLGLLLENIQRVAGRDVLISCTAASSPASRDEFICNFASPSNRSSLIADKDSAALPNGHGMKREDSKGSLNSEGATGSPDQSENIRRSSTRSSVSHCSRLDQFEIRTLLMCYLYIVKMISEDTLLAYWNKFSPQELINVLVLLEVCLFHFRYVGKRNIARVHDAWVSKHGAADRKSQTMPALRSRAGGMQARLQHLGSLDTSFTLNHNAGTSEADIVHQALLEGNIATEVCLTVLDTISFFTQSFKTQLLSNDGHNPLMKKVFDIHLAFLKNGQSEAALKHVFASLRAFISKFPSAFFKGRVNMCAALCYEILKCCTSKVTSTRNEASALLYLLMRNNFEFTKRRTFLRTHLQIIIAVSQLIADVALSGGTRFQDSLLIINNFANSDRPMKATAFPSEVKDLTKRIRTVLMATAQMKEHEKDPEMLIDLQYSLAKSYASTPELRKTWLDSMAKIHVKNGDFSEAAMCYVHVAALVAEFLHRKKLFPSGCTAFRKITPNIDEEGAMKEDGGMMDVHYSEEVLVELLEQCVDGLWKAERYETISEVSKLIIPIYEKRREFEKLTQLYRTLHGAYAKILEVMHTRKRLLGTFFRVAFYGQTFFEEEDGKEYIYKEPKLTGLSEISFRLLKLYGEKFGSETVKIIQDSNKVNIKDLDPRYAHIQVTYVKPYFEDKEISERKTEFERNHNINRFVFETPYTLSGKKHGSVEEQCKKRTILTTLNSFPYVKKRIPVNYEHQVNLKPIDVATDEIKDKTAELQKLCSASDVDMIQLQLKLQGCVSVQVNAGPLAYARAFLSDSQSSKYPAKKVNELKEMFRKFIQACGIALELNERLIKEDQVEYHEGLKSNFRDMVKELSDIIHEQL", "length": 2029, "header": "tr|A0A8V0YHZ1-1|A0A8V0YI06_CHICK Computationally mapped isoform of Dedicator of cytokinesis 11 OS=Gallus gallus OX=9031 GN=DOCK11 PE=3 SV=1 CANONICAL=A0A8V0YI06-1" }, "locus": { "chromosome": "4", "start_pos": 3341722, "end_pos": 3272796, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010035166.1", "url": "https://www.ensembl.org/id/ENSGALT00010035166.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020507.1", "url": "https://www.ensembl.org/id/ENSGALP00010020507.1" } ] } }, { "isoform_ac": "A0A8V0YI06-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI06/entry#A0A8V0YI06-1", "sequence": { "sequence": "MSEVRKFTKRLSKPGTAAELRQSVSEAVRSSFALEKTKVVEPLDYENVILQRKVQIYSDPLRDLLIFPIEDVSLSVISRQRRTVQSTVPEDALKKAQSLFVKECIKTYSSDWHVVNYKYEEYSGDFRMLPCKSFRPDKIPSHVFEIDEDFEKDEDSSSLCSQKGGVIKQGWLHKANVNSTITVTMRVFKRRYFYLSQLTDGSYILNSYKDEKISKESKGCIFLDACNDVVQCPKMRRYAFELKTIDKYSHYLAAESEQEMEEWLVTLRKIIQSNTESSVQEKKDTVEAAQDDESSTQGKSENILESLERSMHPELMKYGRETDQLNKLSRNDGRQNLFSFDPEVQRLDFSGMEPDVKPFEEKSSRRFVVCCQDLSLNLLAQLSDQSEGGPTNVEPFFLSLALFDLKNNCKISADFHVDLNPPPVRDMLLDTSASKVEDVKGRSPGESLMHGIPESCLRYIKRGVFSVTDPHAEIFLVARVEKVLQGSITHCAEPYMKNSDPGKTAQKVHKVAKQVCSRLGLYRMPFGWAARPVFKDSQGTLDAEGKFSPLYKQDSGKLSNEDMLKLLAEYKKPEKTKLQIIPAQLNIVIKDIPLDFTNCVTASYIPIKPFEKSCENIAVEVEELVPEVAKYCYPFTVYKNHLYVYPLHLKYENQKVFAKARNIAVCIEFRDSDEADARPLKCIYGKPGGQLLTSNAYAAVLHHNQSPEFYDEIKIELPIHLHQKHHLLFTFYHVSCEINTKATSKKQDTVETQVGYAWVPLLKDGRIVTLERHLPVSSNLPPGYLGLGDTESRRQSSVDAKWVDGAKPLFKIRIHLDSTIYTQDMHLHKFFQYCQLVQAGVKEVPGELVKYLKCLHAMETQVMIQFLPVILMQLFRVLTNVTQEDEVAVNCTMVLLHIVSKCHEEGLDHYLRSFIKYVFRAEKPSVTQAKMTHEILVLSMATILKQSADFLAINKLLKYSWFFFEALAKSMAIYLLEENKIKLPRAQRFPDSYQHALHSLLLAIIPHVTIRYNEIPEESRNANFSLANFLKRCLTFMDRGFVFNLINDYISGFSPKDPKLLVEYKFEFLQTICNHEHYIPLNLPMTFSKPKLQRAQDVNLEYSLTDEYCRHHFLVGMLLRETSVALQDNYDIRCTAITVLKNLLIKHAFDNRYQHKNQQAKIVQLYLPLLGLLLENIQRVAGRDVLISCTAASSPASRDEFICNFASPSNRSSLIADKDSAALPNGHGMKREDSKGSLNSEGATGSPDQSENIRRSSTRSSVSHCSRLDQFEIRTLLMCYLYIVKMISEDTLLAYWNKFSPQELINVLVLLEVCLFHFRYVGKRNIARVHDAWVSKHGAADRKSQTMPALRSRAGGMQARLQHLGSLDTSFTLNHNAGTSEADIVHQALLEGNIATEVCLTVLDTISFFTQSFKTQLLSNDGHNPLMKKVFDIHLAFLKNGQSEAALKHVFASLRAFISKFPSAFFKGRVNMCAALCYEILKCCTSKVTSTRNEASALLYLLMRNNFEFTKRRTFLRTHLQIIIAVSQLIADVALSGGTRFQDSLLIINNFANSDRPMKATAFPSEVKDLTKRIRTVLMATAQMKEHEKDPEMLIDLQYSLAKSYASTPELRKTWLDSMAKIHVKNGDFSEAAMCYVHVAALVAEFLHRKKLFPSGCTAFRKITPNIDEEGAMKEDGGMMDVHYSEEVLVELLEQCVDGLWKAERYETISEVSKLIIPIYEKRREFEKLTQLYRTLHGAYAKILEVMHTRKRLLGTFFRVAFYGQTFFEEEDGKEYIYKEPKLTGLSEISFRLLKLYGEKFGSETVKIIQDSNKVNIKDLDPRYAHIQVTYVKPYFEDKEISERKTEFERNHNINRFVFETPYTLSGKKHGSVEEQCKKRTILTTLNSFPYVKKRIPVNYEHQVNLKPIDVATDEIKDKTAELQKLCSASDVDMIQLQLKLQGCVSVQVNAGPLAYARAFLSDSQSSKYPAKKVNELKEMFRKFIQACGIALELNERLIKEDQVEYHEGLKSNFRDMVKELSDIIHEQIYHEDPMHSPWMHDSLHVFCAISGTSSNGSYCSLRPTAEI", "length": 2068, "header": "tr|A0A8V0YI06-1|A0A8V0YI06_CHICK Isoform 1 of Dedicator of cytokinesis 11 OS=Gallus gallus OX=9031 GN=DOCK11 PE=3 SV=1 CANONICAL=A0A8V0YI06-1" }, "locus": { "chromosome": "4", "start_pos": 3341948, "end_pos": 3272796, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010035200.1", "url": "https://www.ensembl.org/id/ENSGALT00010035200.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020522.1", "url": "https://www.ensembl.org/id/ENSGALP00010020522.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:422229", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422229", "resource": "KEGG Pathway" }, { "id": "R-GGA-9013148", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013148", "resource": "Reactome", "description": "CDC42 GTPase cycle" }, { "id": "R-GGA-9013149", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013149", "resource": "Reactome", "description": "RAC1 GTPase cycle" }, { "id": "R-GGA-983231", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983231", "resource": "Reactome", "description": "Factors involved in megakaryocyte development and platelet production" } ], "orthologs": [ { "uniprot_canonical_ac": "A2AF47-1", "protein_name": "Dedicator of cytokinesis protein 11", "gene_name": "Dock11", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAEVRKFTKRLSKPGTAAELRQSVSEAVRGSVVLEKAKLVEPLDYENVITQRKTQIYSDPLRDLLMFPMEDISISVIGRQRRTVQSTVPEDAEKRAQSLFVKECIKTYSTDWHVVNYKYEDFSGDFRMLPCKSLRPEKIPNHVFEIDEDCEKDEDSSSLCSQKGGVIKQGWLHKANVNSTITVTMKVFKRRYFYLTQLPDGSYILNSYKDEKNSKESKGCIYLDACIDVVQCPKMRRHAFELKMLDKYSHYLAAETEQEMEEWLIMLKKIIQINTDSLVQEKKDTVEAIQEEETSSQGKAENIMASLERSMHPELMKYGRETEQLNKLSRGDGRQNLFSFDSEVQRLDFSGIEPDVKPFEEKCNKRFMVNCHDLTFNILGHIGDNAKGPPTNVEPFFINLALFDVKNNCKISADFHVDLNPPSVREMLWGTSTQLSNDGNAKGFSPESLIHGIAESQLCYIKQGIFSVTNPHPEIFLVVRIEKVLQGNITHCAEPYIKNSDPIKTAQKVHRTAKQVCSRLGQYRMPFAWAARPIFKDVQGSLDLDGRFSPLYKQDSSKLSNEDILKLLSEYKKPEKTKLQIIPGQLSITVECVPVDLPNCITSSYVPLKPFEKNCQNITVEVEEFVPEMTKYCYPFTIYKNHLYVYPLQLKYDSQKSFAKARNIAVCVEFRDSDESDASALKCIYGKPAGSVFTTNAYAVVSHHNQNPEFYDEIKIELPIHLHQKHHLLFTFYHVSCEINTKGTTKKQDTVETPVGFAWVPLLKDGRVITLEQQLPVSANLPPGYLNVNDAESRRQSNADIKWVDGAKPLLKIKTHLESTIYTQDLHVHKFFHHCQLIQSGSKEVPGELIKYLKCLHAMEIQVMIQFLPVILMQLFRVLTNMTHEDDVPINCTMVLLHIVSKCHEEGLESYLRSFIKYSFRPEKPSTLQAQLIHETLATTMIAILKQSADFLAINKLLKYSWFFFEIIAKSMATYLLEENKIKLPRGQRFPEAYHHVLHSLLLAIIPHVTIRYAEIPDESRNGNYSLASFLKRCLTLMDRGFVFNLINDYISGFSPKDPKVLAEYKFEFLQTICNHEHYIPLNLPMAFAKPKLQRVQDSNLEYSLSDEYCKHHFLVGLLLRETSIALQDNYEIRYTAISVIKNLLIKHAFDTRYQHKNQQAKIAQLYLPFVGLLLENIQRLAGRDTLYSCAAMPSSASRDEFPCGFVSPTNRGSLASDKDTAYGSFQNGHGIKREDSRGSLIPEGATGFPDPGSTSENTRQSSSRSSVSQYNRLDQYEIRNLLMCYLYIVKMISEDTLLTYWNKVSPQELINILVLLEVCLFHFRYMGKRNIARVHDAWLSKHFGIDRKSQTMPALRNRSGVMQARLQHLSSLESSFTLNHSSATTEADIFHQALLEGNTATEVSLTVLDTISFFTQCFKNQLLNNDGHNPLMKKVFDIHLAFLKNGQSEVSLKHVFASLRSFISKFPSAFFKGRVNMCAAFCYEVLKCCTSKISSTRNEASALLYLLMRNNFEYTKRKTFLRTHLQIIIAVSQLIADVALSGGSRFQESLFIINNFANSDRPMKATAFPTEVKDLTKRIRTVLMATAQMKEHEKDPEMLIDLQYSLAKSYASTPELRKTWLDSMAKIHIKNGDFSEAAMCYVHVAALVAEFLHRKKLFPSGCSAFKKITPNIDEEGAMKEDAGMMDVHYSEEVLLELLEQCVDGLWKAERYEVISEISKLIIPIYEKRREFEKLTQVYRTLHGAYTKILEVMHTKKRLLGTFFRVAFYGQSFFEEEDGKEYIYKEPKLTGLSEISLRLVKLYGEKFGTENVKIIQDSDKVNAKELDPKFAHIQVTYVKPYFDDKELTERKTEFERNHNINRFVFEAPYTLSGKKQGCIEEQCKRRTILTTSNSFPYVKKRIPINCEQQVNLKPIDVATDEIKDKTAELHKLCSSVDVDMIQLQLKLQGCVSVQVNAGPLAYARAFLNESQANKYPPKKVNELKDMFRKFIQACSIALELNERLIKEDQIEYHEGLKSNFRDMVKELSDIIHEQILQEDTMHSPWMNNTLHVFCAISGTSSNRGYGSPRYAEV", "length": 2073 }, "evidence": [ { "id": "A0A8V0YI06", "url": "https://omabrowser.org/oma/group/A0A8V0YI06/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "B0R034-1", "protein_name": "Dedicator of cytokinesis protein 11", "gene_name": "dock11", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSEVRKFTKRLSKPGTAAELRQSVSEAVRTSIAVEQPKIIEPLDYENVVFQRKAQIHSDPQRDLLLWPADDVSEAHIDRHRRTINPSVPQNAENEAKSLFAKECIKMYNTNWHVINYNYEAYSGDFRMLPCKGMKTEKLPSQVFEVDEGEEDSSSLCSQRGGVMKQGWLQKANINSSLSVSMKVFKRRYFYLSQLPDGSYILNSYKDEKNYKESKGSIYLDSCIDVVPCPKMRRNGFELKMQERYSHYLAADSEAEMEDWVNTIKQALLSTMEDRRNGSETSEGSLDDDSSSQGKPESITESFGRSLHPELMKYARETDQLSKMSRNEGRQKIFSLDPEVQRLDFSGIEPDVKPFEERFGRRIMVSCHNLTFNLQGCVSEKNDGVLTNVEPFFISLALFDLSKGCKISADFHVDLNPPCVREMIQTGSAGTPTEAGEDENDPVKMNGHGLPLLQRVAESLLHFPTQGIFSVTNPHADIFLLARVEKVLQNGITHCADPYIKPSDISKTVQKVLKTAKQTCQRLGQYRMPFAWAAKQVFKDSQGTLDTDGKFSPLYRQDSSKISTEDLIKLLTDLKKPEKNKLQIIPGQINITVECVPPDLSNSVTSSYIPVKPFADQCDSVSVEVEEFVPEEARFNHPFTIYNNHLYIYPQQLKYDSQKAFDKARNIAVCVQFKDSDEEGSSPLKCIYGKPGDPLFTTSAFAAVLHHNQSPEFYDEIKIELPVHIHEKHHILFTFYHISCDLGTKTTSKKREGVETLVGYSWTPLLKDGRIKSSDLQLPVSANLLAGYLCDKSQDIKKVFPYIKWVDNAKPLFKVRAYVASTIYTQDLHLHNFFQHCQLMRSTSQGNPAELIKYLKCLHAVETQVVIKFLPTVLVQLFEVLSMASKEGQDVAVNSTRVIIHIVSQCHEEGLEHYLRSFLKYVFRINNATSENSVTTHEVLATAVTVILKQTADINTCNKLLKYSWFFFETMARSMAQYLMDGNRMKMPRAQRFPESFQQALQCLLLSIMPHITIRYVEIPEEARCVNFSLACFIKRCLTFMNRGFAFSLINDYMCGFSLKDPKVLTEMKFDFLMTVCNHEHYIPLNLPMAFGRTKLQRVQDFISYAAECFGVVDQSLEYSLTEDYCKNHFLVGLLLREVADGLQACPEIRQLAVAVLKNLMIKHAMDDRYNAFKNQQARICLLYLPLFELLYQNLSQMNSPRQMCRNGLGLMYRDDLSVDSRRSSTIVDKEPSGSVTQNGLSRRGESRGSMYGDPGTPDINELHRRGSTMSTVPAAGRLGQYEIRGLLLCYLHIVRTLSDDTLTAYWSKVNPQDIMNFLSLLEICIIQFRYVGRRNISRSQEPWVSKLFSPERKSQTMPVLRGRASLMQAKLQQFSTMDTSLTLNMAGGPTEAEINHQSLLEGNTSTEVCLTVLDVLSLFTQSFKNQLLDSDGHNALMTKIFDTYLTLLKVGQSETAIKHIFASLRAFIVKFQVPLFKGRVVLCGSLCYEVLKCCMSKLSVLRGEASALLYLLMRHNFDYTKRKSFLRVHLQIIIAVSQLIADVALTGSSRFQESLSIINNFANSDKIMKTTTFPSEVKGLTMRIRTVLMATAQMREHEKDPEMLLDLQYSLARSYASTPELRRTWLDSMARAHSKNGDFSEAAMCNVHVAALMAEYLHRKKLFPSGLAAFKRTTQNIDEEGAMKEDIGMQDVYYTEDVLVEQLEVCVESLWKAERFELITHIARLIIPVYEKRHEFEKLRRLYDTLQRAYAKILEVMQSGRRLLGTYFRVAFFGQGFFEEEDGKEYIYKEPKLTTLPEISHRLLKLYGEKFGSENVKIIQDSNKVNQKDLDSKFAYIQVTYVKPFFDEKEMAERKTDFEKCHNIQRFVFETPFTLTGKKQGGVEEQCKRRTVLTTANTFPYVKKRIEVVGEKHTELKPIDVAIDEMKEKSSELAKLCSNQEVNMITLQLKLQGCVSVQVNAGPMAYARAFLDESKSGQSNKKVKDLKEIFRQFVNACSMALDINERLIKEDQYEYHEGLKANFKSMVKELSEIIHEQIFQEDMMRSLLQNSLHVFRAISGTSTDLS", "length": 2067 }, "evidence": [ { "id": "A0A8V0YI06", "url": "https://omabrowser.org/oma/group/A0A8V0YI06/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1LQ91-1", "protein_name": "Dedicator of cytokinesis 11", "gene_name": "Dock11", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAEVRKFTKRLSKPGTAAELRQSVSEAVRGSVVLEKAKLVEPLDYENVITQRKTQIYSDPLRDLLMFPMEDISLSVIGRQLRTVQSTVPEDAEKRAQSLFVKECIKTYSTDWHVVNYKYEDFSGDFRMLPCKSLRPEKIPNHVFEIDEDCEKDEDSSSLCSQKGGVIKQGWLHKANVNSTITVTMKVFKRRYFYLTQLPDGSYILNSYKDEKNSKESKGCIYLDACIDVVQCPKMRRHAFELKMLDKYSHYLAAETEQEMEEWLITLKKIIQINTDSLVQEKKETVEAIQEEETSSQGKAENIMASLERSMHPELMKYGRETEQLNKLSRGDGRQNLFSFDSEVQRLDFSGIEPDVKPFEEKCNKRFLVNCHDLTFNILGHIGDNAKGPPTNVEPFFITLALFDVKNNCKISADFHVDLNPPSVREMLWGMSTQLANDGNTKGSSPESLIHGIAESRLCYIRQGIFSVTNPHPEIFLVVRIEKVLQGNITHCAEPYIKNSDPIKTAQKVHRTAKQVCSRLGQYRMPFAWAARPIFKDLQGSLDLDGKFSPLYKQDSSKLSNEDILKLLSEYKKPEKTKLQIIPGQLNITVECVPVDLPNCITSSYVPLKPFEKNCQNITVEVEEFVPEMTKYCYPFTIYKNHLYVYPLQLKYDSQKSFAKARNIAVCVEFRDSDESDTSALKCIYGKPAGSVFTTNAYAVVSHHNQNPEFYDEIKIELPIHLHQKHHLLFTFYHVSCEINTKGTTKKQDTVETPVGFAWVPLLKDGRVTTLEQQLPVSANLPPGYLNVNDAESRRQSNADIKWVDGAKPLLKIKTHLESTIYTQDLHVHKFFHHCQLIQSGSKEVPGELIKYLKCLHAMEIQVMIQFLPVILMQLFRVLTNMTHEDDVPINCTMVLLHIVSKCHEEGLESYLRSFIKYSFRPEKPSTLQAQLIHETLATTMIAILKQSADFLAINKLLKYSWFFFEIIAKSMATYLLEENKIKLPRGQRFPEAYHHILHSLLLAIIPHVTIRYAEIPDESRNVNYSLASFLKRCLTLMDRGFVFNLINDYISGFSPKDPKVLAEYKFEFLQTICNHEHYIPLNLPMAFAKPKLQRVQDSNLEYSLSDEYCKHHFLVGLLLRETSIALQDNYEIRYTAISVIKNLLIKHAFDTRYQHKNQQAKIAQLYLPFVGLLLENIQRLAGRDTLYSCAAMPNSASRDEFPCGFVSPTSRGSLATDKEPAYGSFQNGHGIKREDSRGSLIPEGATGFPDPGSTGENTRQSSSRTSVSQYNRLDQYEIRNLLMCYLYIVKMISEDTLLTYWNKVSPQELINILVLLEVCLFHFRYMGKRNIARVHDAWLSKHFGIDRKSQTMPALRNRSGVMQARLQHLSSLESSFTLNHSSATTEADIFHQALLEGNTATEVSLTVLDTISFFTQCFKSQLLNNDGHNPLMKKVFDIHLAFLKNGQSEVSLKHVFASLRSFISKFPSAFFKGRVNMCAAFCYEVLKCCTSKISSTRNEASALLYLLMRNNFEYTKRKTFLRTHLQIIIAVSQLIADVALSGGSRFQESLFIINNFANSDRPMKATAFPTEVKDLTKRIRTVLMATAQMKEHEKDPEMLIDLQYSLAKSYASTPELRKTWLDSMAKIHIKNGDFSEAAMCYVHVAALVAEFLHRKKLFPSGCSAFKKITPNIDEEGAMKEDAGMMDVHYSEEVLLELLEQCVDGLWKAERYEVISEISKLIIPIYEKRREFEKLTQVYRTLHGAYTKILEVMHTKKRLLGTFFRVAFYGQSFFEEEDGKEYIYKEPKLTGLSEISFRLVKLYGEKFGTENIKIIQDSDKVNAKELDPKFAHIQVTYVKPYFDDKELTERKTEFERNHNINRFVFEAPYTLSGKKQGCIEEQCKRRTILTTSNSFPYVKKRIPITCEQQVNLKPIDVATDEIKDKTAELHKLCSSADVDMIQLQLKLQGCVSVQVNAGPLAYARAFLNESQANKYPPKKVNELKDMFRKFIQACSIALELNERLIKEDQIEYHEGLKSNFRDMVKELSDIIHEQILQEDTMHSPWMNNTLHVFCAISGTSSNRGYGSPRYSEV", "length": 2073 }, "evidence": [ { "id": "A0A8V0YI06", "url": "https://omabrowser.org/oma/group/A0A8V0YI06/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G5E580-1", "protein_name": "Dedicator of cytokinesis 11", "gene_name": "DOCK11", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAEVRKFTKRLSKPGTAAELRQSVSEAVRSSVVLEKTKVVEPLDYENVIAQRKTQIYSDPLRDLLMFPMEDISISVISRQRRTVQSTVPEDGEKRAQSLFVKECIKTYSTDWHVVNYKYEDFSGDFRMLPCKSLRPEKIPNHVFEIDEDCEKDEDSSSLCSQKGGVIKQGWLHKANVNSTITVTMKVFKRRYFYLTQLPDGSYILNSYKDEKNSKESKGCIYLDACIDVVQCPKMRRHAFELKMLDKYSHYLAAETEQEMEEWLITLKKIIQINTDSLVQEKKETVEISQDDEPSSQGKAENIMASLERSMHPELMKYGRETEQLNKLSRGDGRQNLFSFDSEVQRLDFSGIEPDIKPFEEKCNKRFLVNCHDLMFNILGQVGDNAKGPPTNVEPFFINLALFDVKNNCKISADFHVDLNPPSVREMLWGPSSQPATDGTPRGSSPESFIHGIAESQLRFIKQGIFSVTNPHPEIFLVARIEKVLQGNITHCAEPYIKNSDPAKTAQKVHRTAKQVCSRLGQYRMPFAWAARPIFKDIQGSLDVDGRFSPLYKQDSSKLSNEDILKLLSEYKKPEKTKLQIIPGQLNITVECVPVDFSNCITSSYVPLKPFEKNCQNITVEVEEFVPEMTKYCYPFTIYKNHLYVYPLQLKYDSQKTFAKARNIAVCVEFRDSDESDASALKCIYGKPAGSVFTTNAYAVVSHHNQNPEFYDEIKIELPIHLHQKHHLLFTFYHVSCEINTKGTTKKQDTVETPVGFAWVPLLKDGRIITLEQQLPVSANLPPGYMNLNDAESRRQPNVDIKWVDGAKPLLKIKSHLESTIYTQDLHVHKFFQHCQLIQSGSKEVPGELIKYLKCLHAMEIQVMIQFLPVILMQLFQVLTNMTHEDDVPFNCTMVLLHIVSKCHEEGLDNYLRSFIKYSFRPEKPSAPQAQLIHETLATTMIAILKQSADFLAINKLLKYSWFFFEIIAKSMATYLLEENKIKLPRGQRFSEAYHHVLHSLLLAIIPHVTIRYAEIPDESRNVNYSLASFLKRCLTLMDRGFVFNLINDYISGFSPKDPKVLAEYKFEFLQTICNHEHYIPLNLPMAFAKPKLQRVQDSNLEYSLSDEYCKHHFLVGLLLRETSIALQDNYEIRYTAISVIKNLLIKHAFDTRYQHKNQQAKIAQLYLPFVGLLLENIQRLAGRDTLYSCAAMPNSASRDEFACGFTSPTNRGSLSTDKDTAYGSFQNGHGIKREDSRGSLIPEGATGFPDQGSTGENTRQSSTRSSVSQYNRLDQYEIRSLLMCYLYIVKMISEDTLLTYWNKVSPQELINILILLEVCLFHFRYMGKRNIARVHDAWLSKHFGVDRKSQTMPALRNRSGIMQARLQHLSSLESSFTLNHSSSTTEADIFHQALLEGNTATEVSLTVLDTISFFTQCFKSQLLNNDGHNPLMKKVFDIHLAFLKNGQSEVSLKHVFASLRAFISKFPSAFFKGRVNMCAAFCYEVLKCCTSKISSTRNEASALLYLLMRNNFEYTKRKTFLRTHLQIIIAVSQLIADVALSGGSRFQESLFIINNFANSDRPMKATAFPSEVKDLTKRIRTVLMATAQMKEHEKDPEMLIDLQYSLAKSYASTPELRKTWLDSMAKIHIKNGDFSEAAMCYVHVAALVAEFLHRKKLFPNGCSAFKKITPNIDEEGAMKEDAGMMDVHYSEEVLLELLEQCVDGLWKAERYEVISEISKLIIPIYEKRREFEKLTQVYRTLHGAYTKILEVMHTKKRLLGTFFRVAFYGQSFFEEEDGKEYIYKEPKLTGLSEISLRLVKLYGEKFGTENVKIIQDSDKVNVKELDPKYAHIQVTYVKPYFDDKELTERKTEFERNHNINRFVFEAPYTLSGKKQGCIEEQCKRRTILTTSNSFPYVKKRIAINYEQQIHLKPIDVATDEIKDKTAELQKLCSSADVDMIQLQLKLQGCVSVQVNAGPLAYARAFLNDSQASKYPAKKVNELKDMFRKFIQACSIALELNERLIKEDQIEYHEGLKSNFRDMVKELSDIIHEQIIQEDPMHSPWMSNTLHVFCAISGTSSDRSYGSPRYTAEM", "length": 2074 }, "evidence": [ { "id": "A0A8V0YI06", "url": "https://omabrowser.org/oma/group/A0A8V0YI06/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q5JSL3-1", "protein_name": "Dedicator of cytokinesis protein 11", "gene_name": "DOCK11", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAEVRKFTKRLSKPGTAAELRQSVSEAVRGSVVLEKAKVVEPLDYENVIAQRKTQIYSDPLRDLLMFPMEDISISVIGRQRRTVQSTVPEDAEKRAQSLFVKECIKTYSTDWHVVNYKYEDFSGDFRMLPCKSLRPEKIPNHVFEIDEDCEKDEDSSSLCSQKGGVIKQGWLHKANVNSTITVTMKVFKRRYFYLTQLPDGSYILNSYKDEKNSKESKGCIYLDACIDVVQCPKMRRHAFELKMLDKYSHYLAAETEQEMEEWLITLKKIIQINTDSLVQEKKETVETAQDDETSSQGKAENIMASLERSMHPELMKYGRETEQLNKLSRGDGRQNLFSFDSEVQRLDFSGIEPDIKPFEEKCNKRFLVNCHDLTFNILGQIGDNAKGPPTNVEPFFINLALFDVKNNCKISADFHVDLNPPSVREMLWGSSTQLASDGSPKGSSPESYIHGIAESQLRYIQQGIFSVTNPHPEIFLVARIEKVLQGNITHCAEPYIKNSDPVKTAQKVHRTAKQVCSRLGQYRMPFAWAARPIFKDTQGSLDLDGRFSPLYKQDSSKLSSEDILKLLSEYKKPEKTKLQIIPGQLNITVECVPVDLSNCITSSYVPLKPFEKNCQNITVEVEEFVPEMTKYCYPFTIYKNHLYVYPLQLKYDSQKTFAKARNIAVCVEFRDSDESDASALKCIYGKPAGSVFTTNAYAVVSHHNQNPEFYDEIKIELPIHLHQKHHLLFTFYHVSCEINTKGTTKKQDTVETPVGFAWVPLLKDGRIITFEQQLPVSANLPPGYLNLNDAESRRQCNVDIKWVDGAKPLLKIKSHLESTIYTQDLHVHKFFHHCQLIQSGSKEVPGELIKYLKCLHAMEIQVMIQFLPVILMQLFRVLTNMTHEDDVPINCTMVLLHIVSKCHEEGLDSYLRSFIKYSFRPEKPSAPQAQLIHETLATTMIAILKQSADFLSINKLLKYSWFFFEIIAKSMATYLLEENKIKLPRGQRFPETYHHVLHSLLLAIIPHVTIRYAEIPDESRNVNYSLASFLKRCLTLMDRGFIFNLINDYISGFSPKDPKVLAEYKFEFLQTICNHEHYIPLNLPMAFAKPKLQRVQDSNLEYSLSDEYCKHHFLVGLLLRETSIALQDNYEIRYTAISVIKNLLIKHAFDTRYQHKNQQAKIAQLYLPFVGLLLENIQRLAGRDTLYSCAAMPNSASRDEFPCGFTSPANRGSLSTDKDTAYGSFQNGHGIKREDSRGSLIPEGATGFPDQGNTGENTRQSSTRSSVSQYNRLDQYEIRSLLMCYLYIVKMISEDTLLTYWNKVSPQELINILILLEVCLFHFRYMGKRNIARVHDAWLSKHFGIDRKSQTMPALRNRSGVMQARLQHLSSLESSFTLNHSSTTTEADIFHQALLEGNTATEVSLTVLDTISFFTQCFKTQLLNNDGHNPLMKKVFDIHLAFLKNGQSEVSLKHVFASLRAFISKFPSAFFKGRVNMCAAFCYEVLKCCTSKISSTRNEASALLYLLMRNNFEYTKRKTFLRTHLQIIIAVSQLIADVALSGGSRFQESLFIINNFANSDRPMKATAFPAEVKDLTKRIRTVLMATAQMKEHEKDPEMLIDLQYSLAKSYASTPELRKTWLDSMAKIHVKNGDFSEAAMCYVHVAALVAEFLHRKKLFPNGCSAFKKITPNIDEEGAMKEDAGMMDVHYSEEVLLELLEQCVDGLWKAERYEIISEISKLIVPIYEKRREFEKLTQVYRTLHGAYTKILEVMHTKKRLLGTFFRVAFYGQSFFEEEDGKEYIYKEPKLTGLSEISLRLVKLYGEKFGTENVKIIQDSDKVNAKELDPKYAHIQVTYVKPYFDDKELTERKTEFERNHNISRFVFEAPYTLSGKKQGCIEEQCKRRTILTTSNSFPYVKKRIPINCEQQINLKPIDVATDEIKDKTAELQKLCSSTDVDMIQLQLKLQGCVSVQVNAGPLAYARAFLNDSQASKYPPKKVSELKDMFRKFIQACSIALELNERLIKEDQVEYHEGLKSNFRDMVKELSDIIHEQILQEDTMHSPWMSNTLHVFCAISGTSSDRGYGSPRYAEV", "length": 2073 }, "evidence": [ { "id": "A0A8V0YI06", "url": "https://omabrowser.org/oma/group/A0A8V0YI06/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "guanyl-nucleotide exchange factor activity", "id": "GO:0005085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005085", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YI06", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI06" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "small GTPase-mediated signal transduction", "id": "GO:0007264", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007264", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YI06", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI06" } ], "pmid": "" }, { "name": "regulation of Rho protein signal transduction", "id": "GO:0035023", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035023", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YI06", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI06" } ], "pmid": "" }, { "name": "positive regulation of filopodium assembly", "id": "GO:0051491", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051491", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YI06", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI06" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1023, "end_pos": 1025, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1210, "end_pos": 1212, "annotation": "n_glycosylation_sequon" }, { "start_pos": 178, "end_pos": 180, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2056, "end_pos": 2058, "annotation": "n_glycosylation_sequon" }, { "start_pos": 704, "end_pos": 706, "annotation": "n_glycosylation_sequon" }, { "start_pos": 880, "end_pos": 882, "annotation": "n_glycosylation_sequon" }, { "start_pos": 890, 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}, { "start_pos": 704, "end_pos": 706 }, { "start_pos": 880, "end_pos": 882 }, { "start_pos": 890, "end_pos": 892 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": 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"UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHZ7/entry#names_and_taxonomy" } ] }, { "name": "laminin subunit gamma-1", "type": "synonym", "evidence": [ { "id": "XP_040561204", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040561204" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052539.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040561204", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040561204" } ] }, { "annotation": "Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHZ7#function" }, { "database": "UniProtKB", "id": "ARBA00002418", "url": "https://www.uniprot.org/uniprotkb/ARBA00002418#function" }, { "database": "UniProtKB", "id": "A0A8V0YB27", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB27#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": 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"https://www.ebi.ac.uk/interpro/entry/pfam/PF24973", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_040561204", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040561204", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YB27", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB27", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YB27-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB27-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHZ7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHZ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHZ7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGGVGGRRALLRVLALLAVLALPRGGGAAMDECTEERSGRPQRCMPEFVNAAFNATVVATNTCGTPAEEYCVQTGVTGVTQSCHLCDASQPHLRHGASFLTDYNSQADSTWWQSQSMLAGVQHPAAVNLTLHLGKAFDITYVRLKFHTSRPESFAIYKRTREDGPWVPYQYYSGSCESTYNKVNRGFIRTGEDEQQALCTDEFSDISPLTGGNVAFSTLEGRPSAYNFDNSPVLQEWVTATDIRVSLNRLNTFGDEVFNDPKVLKSYYYAISDFAVGGRCKCNGHASECIRNELGKLVCNCKHNTFGDDCEKCLPFFNDRPWRRATAESANECLPCDCNGRSQECYFDPELYRSTGHGGHCMGCRDNTDGAHCERCRDSFYRLGSEEGCLPCSCNPVGSLSTQCDSYGQCSCKPGVMGEKCDRCQPGFHSLSEAGCRPCSCNPAGSTGECNMETGRCTCKDNVEGFHCERCKPGFFHLDPSNPRGCTPCFCFGHSSVCTNAVGYSVYSITSSFQFGEDEWHAEQRDGSQVPLQWSSETQDISVISDSYFPIYFVAPRKFLGNQVLSYGQNLTFSFRVDRRDTRLSAEDLVLEGAGLRVSVPLIAQGNSYPSESPLTYTFRLHEAADYPWRPALSAFDFQKLLHNLTAIKIRGTYSERSAGHLDDVTITSAVPGAGVPAAWVESCSCPAGYEGQFCERCSPGYRRETPSLGPYSPCVPCTCNGHSETCDPETGVCDCRDNTAGSHCEKCSDGYYGDATAGTALDCQPCPCPGGSSCAVVPRTKEVVCTSCQTGTTGKRCELCDDAYFGDPLGENGAVRPCRLCQCNDNIDPNAVGNCNRQTGECLKCIYNTAGFYCDRCKDGFFGNPLATNPADKCRACHCNPYGTVNQQTSCNQVTGQCECLSHVTERDCSACEPGFFNLQSGRGCERCDCHALGSTNGQCDIWTGQCECQPGVTGQRCDRCEANHFGFGPEGCKPCDCDPEGSRALQCREDGRCECKEGFVGSRCDQCEENYFYNRSWPGCQECPACYRLVKDKVAEQRERLRELENLIANLGTGEETITDQAFEERLKQAERDVMELLREAQNSKDVDQGLMDRLRDINSTLTSQLSRLRNIQNTVQETENLAEQARGRVEDTEDLIAMASDMLEKAKMAAGNVSITPPESSSDPNNMTLLAEEARRLAERHKQEADEIVRIAKAANDTSTEAYQLLLKTLAGENQTARDIDELNQKYNQARNISRDLERQANRVLEEAEEAGNKALQIYANLTNLPTVDTTGLENEANKIKKEAEELDQLTARKLKDYEDLREDMKGKELEVKNLLEKGKTEQQTADQLLARADAAKALAEEAARKGNGTLQEANTILSNLKDFDKRVNDNKTAAEEALKKIPAITQTIAEANNKTRQAELALGNAAADAREAKTRADDAEKIASAVQKSAAATRAEADKTFSDVTGLAREVDDMMKQLQEAEKELKRKQDDADQDMMMAGMASQAAQEAEDNARKAKNSVNSLLAVINDLLDQLGQLETVDLNKLNEIEGTLNSAKDQMKDSDLDQKVAFLEREARKQDDAIQSYNRDIEEILKDISNLEDIRKTLPSGCFNTPSIEKP", 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"length": 1593, "header": "tr|A0A8V0YB27-1|A0A8V0YB27_CHICK Computationally mapped isoform of Laminin subunit gamma 1 OS=Gallus gallus OX=9031 GN=LAMC1 PE=1 SV=1 CANONICAL=A0A8V0YHZ7-1" }, "locus": { "chromosome": "8", "start_pos": 7518729, "end_pos": 7469674, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027391.1", "url": "https://www.ensembl.org/id/ENSGALT00010027391.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015645.1", "url": "https://www.ensembl.org/id/ENSGALP00010015645.1" } ] } }, { "isoform_ac": "A0A8V0YHZ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHZ7/entry#A0A8V0YHZ7-1", "sequence": { "sequence": 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"length": 1603, "header": "tr|A0A8V0YHZ7-1|A0A8V0YHZ7_CHICK Isoform 1 of Laminin subunit gamma 1 OS=Gallus gallus OX=9031 GN=LAMC1 PE=1 SV=1 CANONICAL=A0A8V0YHZ7-1" }, "locus": { "chromosome": "8", "start_pos": 7518729, "end_pos": 7469674, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027390.1", "url": "https://www.ensembl.org/id/ENSGALT00010027390.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015644.1", "url": "https://www.ensembl.org/id/ENSGALP00010015644.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "Q1LVF0-1", "protein_name": "Laminin subunit gamma-1", "gene_name": "lamc1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSLFSCLLLWTLWAACSHGAMDECIDEDDRPQRCMPEFVNAAFNATVVATNTCGSPPEEFCVQTGVTGVTKSCHICNAADPRLHHGAVYLTDYNQPVQPTWWQSQTMLAGIQYPNSINLTLHLGKSFDITYVRLKFHTSRPESFAIYKRSSEDGPWTPYQYYSGSCEKTYSKNNRGFIRTGEDEQQALCTDEFSDISPLYGGNVAFSTLEGRPSAYNFDNSPVLQDWVTATDIRVTLNRLNTFGDEVFNDPKVLKSYYYAISDFAVGGRCKCNGHASECVKNEYSKLVCNCKHNTEGADCNVCKPFYNDRPWRRATAENPNECLPCNCNGKSAECYFDPELYRATGHGGHCRNCADNTDGPKCERCLANYYREASGQRCLSCGCNPVGSLSTQCDNTGRCSCKPGVMGDKCDRCQPGYHSLSEAGCRPCSCNPAGSTQECDVQTGRCQCKENVDGFNCDRCKLGYFNLDPQNPQGCTPCFCFQHSTVCESADGYSVHKITSTFDRDDEGWKGKQRDDSSVPVQWSPSSGEISLISEDYFPIYFVAPDKFLHNQLLSYGQNLTLNFRIQRHDARLSAEDVVLEGSGLRVAVPLIAQGNSYPGEETQTFVFRLHDTTDYPWRPTIKHADFQKLLYNLTSIMIRGTYSAQSAGYLDNVSLVTARRGPGTPARWVEKCTCPQGYLGQHCEQCDQGFRRSRPELRRFSTCERCNCNGHSDTCDPETGMCNCQHNTAGLSCERCKDGFYGDSTVGSSSDCKACPCPAGATCAVVPKTNEVVCTNCPTGTTGKRCELCDDGFFGDPLGEKGPVRACRACSCNNNIDPNAVGNCNRESGECLKCIYNTAGVFCDRCKQGFYGDARAANVADKCKPCKCSPYGTVDRQTACSQVTGQCPCLPHVINRDCGACELGFYNLQSGKGCERCNCNPIGSTNGQCDIVSGQCECQPGVTGQHCERCEVNFFGFSSSGCKPCDCDPEGSESAQCKEDGRCHCRPGFVGSRCDMCEENYFYNRSTPGCQQCPNCYSLVRDKVNQQRQKLLDLQNLIDSLDNTETTVSDKAFEDRLKEAEKTIMDLLEEAQASKEVDKGLLDRLNNINKTLNNQWNRLQNIKNTVDNTGAQADRARNRVRDAENLINTAREELDKAKEAISKVDIKIPTTSGDPNNMTLLAEEARKLSEKHKADADQIEKIAKDANDTSTKAYNMLKKALDGENKTSSDIDELNRKYLEAKDLAKNLEKQAAKVHAEAEEAGNKALKIYANLTSLPPINTKTLEDDANKIKKEASDLDKLIDKTEKEYNDLREDLRGKETEVRKLLDKGKTEQQTADQLLARADAAKALAEEAAKKGKSTFQEAQDILNNLRDFDKRVNDNKTAAEDAMRRIPQINATINEANDKTRRAEAALGNAAADAKDAKAKAEEAEKIANDVQKGSAKTKADAEKAFEDTMKLDKDVDKMMDQLTAAEKELEKKKAEADTDMMMASMASDNAKDAEGNARKAKSAVREVLNTINALLGQLGNIDKVDLSKLNQIDNALKDAKDKMAGSELDRKLKELNDIAKSQEDMISDYDRQIQEIRADIANLNDIKNTLPEGCFNTPSLERP", "length": 1593 }, "evidence": [ { "id": "A0A8V0YHZ7", "url": "https://omabrowser.org/oma/group/A0A8V0YHZ7/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 9, "go_terms": [ { "name": "cell migration", "id": "GO:0016477", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016477", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHZ7" } ], "pmid": "" }, { "name": "extracellular matrix disassembly", "id": "GO:0022617", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022617", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHZ7" } ], "pmid": "" }, { "name": "animal organ morphogenesis", "id": "GO:0009887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009887", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHZ7" } ], "pmid": "" }, { "name": "substrate adhesion-dependent cell spreading", "id": "GO:0034446", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034446", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHZ7" } ], "pmid": "" }, { "name": "axon guidance", "id": "GO:0007411", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007411", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHZ7" } ], "pmid": "" }, { "name": "tissue development", "id": "GO:0009888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009888", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHZ7" } ], "pmid": "" }, { "name": "hemidesmosome assembly", "id": "GO:0031581", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031581", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHZ7" } ], "pmid": "" }, { "name": "protein-containing complex assembly", "id": "GO:0065003", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0065003", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHZ7" } ], "pmid": "" }, { "name": "cell adhesion", "id": "GO:0007155", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007155", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHZ7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "basement membrane", "id": "GO:0005604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005604", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHZ7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "extracellular matrix structural constituent", "id": "GO:0005201", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005201", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHZ7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1016, "end_pos": 1018, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1101, "end_pos": 1103, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1155, "end_pos": 1157, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1169, "end_pos": 1171, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1199, "end_pos": 1201, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1217, "end_pos": 1219, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1235, "end_pos": 1237, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1264, "end_pos": 1266, "annotation": "n_glycosylation_sequon" }, { "start_pos": 128, "end_pos": 130, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1351, 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"name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1016, "end_pos": 1018 }, { "start_pos": 1101, "end_pos": 1103 }, { "start_pos": 1155, "end_pos": 1157 }, { "start_pos": 1169, "end_pos": 1171 }, { "start_pos": 1199, "end_pos": 1201 }, { "start_pos": 1217, "end_pos": 1219 }, { "start_pos": 1235, "end_pos": 1237 }, { "start_pos": 1264, "end_pos": 1266 }, { "start_pos": 128, "end_pos": 130 }, { "start_pos": 1351, "end_pos": 1353 }, { "start_pos": 1374, "end_pos": 1376 }, { "start_pos": 1397, "end_pos": 1399 }, { "start_pos": 54, "end_pos": 56 }, { "start_pos": 570, "end_pos": 572 }, { "start_pos": 644, "end_pos": 646 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": 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"uniprot_id": "A0A8V0YI29_CHICK", "mass": { "chemical_mass": 92588.0, "monoisotopic_mass": 92588.0 }, "refseq": {}, "gene_names": [ { "name": "LOC121106719", "type": "recommended", "evidence": [ { "id": "A0A8V0YI29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI29" } ] } ], "protein_names": [ { "name": "Cadherin domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A8V0YI29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI29/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YI29", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI29" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LOC121106719", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI29", "locus": {} } ], "crossref": [ { "id": "A0A8V0YI29", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YI29", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd11304", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11304", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR002126", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002126", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013164", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013164", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015919", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015919", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020894", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020894", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032455", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032455", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050174", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050174", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YDE0", "url": "https://www.orthodb.org/?gene=A0A8V0YDE0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YI29", "url": "https://www.orthodb.org/?gene=A0A8V0YI29", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24028", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24028", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24028:SF234", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24028:SF234", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00028", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00028", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08266", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08266", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16492", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16492", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YDE0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDE0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YDE0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDE0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YI29", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI29", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YI29-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI29-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "GAAVHRGGEEGRALLCCVLVAAWEAVRGQLRYSVPEELPKGSFVGDVAKDLALELAALGARGARVVSPGRTQYFVLHASSGHLVTAERIDREQLCENEPQCVLRCELIVEGEMKVYAIEVEITDINDNTPKFRVEEMKLRMSETTTPGSRFPLRVAQDPDVGVNSLQSYTLSGDEHFSLSVQAGADGEKRPELVLAKALDREEAAFHELLLRASDGGDPARTGTARIRVAVLDANDNAPAFSQAVYTVRVPEDVPVGSTLLRVTATDLDDGTNGDVKYTVNKITDKALKLFHLDAKTGAIKLAMNLDFEEAQSYKLEVHARDGGDLFDTATVSISVTDVNDNAPEISVRSALSEISEDAAPGTVVALLHVQDRDSGANGEVRCSLGEGVPFRLERALDDYYSVVTARELDRERASEYNVTVRAADGGSPALRSGAVLALRVLDVNDNAPVFAEARYSARLPENNAEGALVLTVRAWDADWGQNARVRYRLREGRLRGAPLSSYVSVQAETGALYALRSFDYEEVREVELWVRAEDGGAPPLSSNVSVRLLIADENDNAPQVLYPPAAPGPGWAGVELAPRSAEPGALVAKVVAVDADAGQNAWLSYELAKATEPGLFRVGLHSGEVRTARSPLARDAARHSLVVVVKDRGRPALSATATLTVVLAENVAELLSELGSAAAPAEPAGSLTRWLVLAVAAVSCLFLAFLLLLLALRLRRWRRSRLLPPPSAGAALRGVPASHFVGIDGVRAFLRSYSHDVSLTADSRKSQLRCAGGSCCDTLPARPPPDEAAPLRGEDAAAHRAAEPDGLPVSAATAAAPHSLPSRSPLAPVFDSPWCRVFPSALQVSFDGESVTSTCLFLLLYPNSL", "length": 866, "header": "tr|A0A8V0YI29-1|A0A8V0YI29_CHICK Isoform 1 of Cadherin domain-containing protein OS=Gallus gallus OX=9031 GN=LOC121106719 PE=4 SV=1 CANONICAL=A0A8V0YI29-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YDE0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI29/entry#A0A8V0YDE0-1", "sequence": { "sequence": "RAAPWCGRALLCCVLVAAWEAVRGQLRYSVPEELPKGSFVGDVAKDLALELAALGARGARVVSPGRTQYFVLHASSGHLVTAERIDREQLCENEPQCVLRCELIVEGEMKVYAIEVEITDINDNTPKFRVEEMKLRMSETTTPGSRFPLRVAQDPDVGVNSLQSYTLSGDEHFSLSVQAGADGEKRPELVLAKALDREEAAFHELLLRASDGGDPARTGTARIRVAVLDANDNAPAFSQAVYTVRVPEDVPVGSTLLRVTATDLDDGTNGDVKYTVNKITDKALKLFHLDAKTGAIKLAMNLDFEEAQSYKLEVHARDGGDLFDTATVSISVTDVNDNAPEISVRSALSEISEDAAPGTVVALLHVQDRDSGANGEVRCSLGEGVPFRLERALDDYYSVVTARELDRERASEYNVTVRAADGGSPALRSGAVLALRVLDVNDNAPVFAEARYSARLPENNAEGALVLTVRAWDADWGQNARVRYRLREGRLRGAPLSSYVSVQAETGALYALRSFDYEEVREVELWVRAEDGGAPPLSSNVSVRLLIADENDNAPQVLYPPAAPGPGWAGVELAPRSAEPGALVAKVVAVDADAGQNAWLSYELAKATEPGLFRVGLHSGEVRTARSPLARDAARHSLVVVVKDRGRPALSATATLTVVLAENVAELLSELGSAAAPAEPAGSLTRWLVLAVAAVSCLFLAFLLLLLALRLRRWRRSRLLPPPSAGAALRGVPASHFVGIDGVRAFLRSYSHDVSLTADSRKSQLRCAGGSCCDTLPARPPPDEAAPLRGEDAAAHRAAEPDGLPVSAATAAAPHSLPSRSPLAPVFDSPWCRVFPSALQVSFDGESVTSTCLFLLLYPNSL", "length": 862, "header": "tr|A0A8V0YDE0-1|A0A8V0YDE0_CHICK Computationally mapped isoform of Cadherin domain-containing protein OS=Gallus gallus OX=9031 GN=LOC121106719 PE=4 SV=1 CANONICAL=A0A8V0YI29-1" }, "locus": { "chromosome": "13", "start_pos": 1463384, "end_pos": 1460524, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027424.1", "url": "https://www.ensembl.org/id/ENSGALT00010027424.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015678.1", "url": "https://www.ensembl.org/id/ENSGALP00010015678.1" } ] } }, { "isoform_ac": "A0A8V0YI29-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI29/entry#A0A8V0YI29-1", "sequence": { "sequence": "GAAVHRGGEEGRALLCCVLVAAWEAVRGQLRYSVPEELPKGSFVGDVAKDLALELAALGARGARVVSPGRTQYFVLHASSGHLVTAERIDREQLCENEPQCVLRCELIVEGEMKVYAIEVEITDINDNTPKFRVEEMKLRMSETTTPGSRFPLRVAQDPDVGVNSLQSYTLSGDEHFSLSVQAGADGEKRPELVLAKALDREEAAFHELLLRASDGGDPARTGTARIRVAVLDANDNAPAFSQAVYTVRVPEDVPVGSTLLRVTATDLDDGTNGDVKYTVNKITDKALKLFHLDAKTGAIKLAMNLDFEEAQSYKLEVHARDGGDLFDTATVSISVTDVNDNAPEISVRSALSEISEDAAPGTVVALLHVQDRDSGANGEVRCSLGEGVPFRLERALDDYYSVVTARELDRERASEYNVTVRAADGGSPALRSGAVLALRVLDVNDNAPVFAEARYSARLPENNAEGALVLTVRAWDADWGQNARVRYRLREGRLRGAPLSSYVSVQAETGALYALRSFDYEEVREVELWVRAEDGGAPPLSSNVSVRLLIADENDNAPQVLYPPAAPGPGWAGVELAPRSAEPGALVAKVVAVDADAGQNAWLSYELAKATEPGLFRVGLHSGEVRTARSPLARDAARHSLVVVVKDRGRPALSATATLTVVLAENVAELLSELGSAAAPAEPAGSLTRWLVLAVAAVSCLFLAFLLLLLALRLRRWRRSRLLPPPSAGAALRGVPASHFVGIDGVRAFLRSYSHDVSLTADSRKSQLRCAGGSCCDTLPARPPPDEAAPLRGEDAAAHRAAEPDGLPVSAATAAAPHSLPSRSPLAPVFDSPWCRVFPSALQVSFDGESVTSTCLFLLLYPNSL", "length": 866, "header": "tr|A0A8V0YI29-1|A0A8V0YI29_CHICK Isoform 1 of Cadherin domain-containing protein OS=Gallus gallus OX=9031 GN=LOC121106719 PE=4 SV=1 CANONICAL=A0A8V0YI29-1" }, "locus": { "chromosome": "13", "start_pos": 1463384, "end_pos": 1460405, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027427.1", "url": "https://www.ensembl.org/id/ENSGALT00010027427.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015681.1", "url": "https://www.ensembl.org/id/ENSGALP00010015681.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YI29", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI29" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "cell adhesion", "id": "GO:0007155", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007155", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YI29", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI29" } ], "pmid": "" }, { "name": "homophilic cell adhesion via plasma membrane adhesion molecules", "id": "GO:0007156", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007156", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YI29", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI29" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YI29", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI29" } ], "pmid": "" }, { "name": "cell adhesion molecule binding", "id": "GO:0050839", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050839", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YI29", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI29" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 418, "end_pos": 420, "annotation": "n_glycosylation_sequon" }, { "start_pos": 544, "end_pos": 546, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YI29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI29" }, { "id": "PS50268", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50268" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Cadherin", "eco_id": "ECO_0000259", "start_pos": 73, "end_pos": 132, "start_aa": "Tyr", "end_aa": "Phe", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 418, "end_pos": 420 }, { "start_pos": 544, "end_pos": 546 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YI39-1", "uniprot_ac": "A0A8V0YI39", "uniprot_id": "A0A8V0YI39_CHICK", "mass": { "chemical_mass": 57035.0, "monoisotopic_mass": 57035.0 }, "refseq": {}, "gene_names": [ { "name": "SPINK5", "type": "recommended", "evidence": [ { "id": "A0A8V0YI39", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI39" } ] } ], "protein_names": [ { "name": "Serine peptidase inhibitor, Kazal type 5", "type": "synonym", "evidence": [ { "id": "A0A8V0YI39", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI39/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YI39", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI39" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SPINK5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI39", "locus": { "chromosome": "13", "start_pos": 10169565, "end_pos": 10159365, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010014696", "url": "https://www.ensembl.org/id/ENSGALG00010014696" } ] } } ], "crossref": [ { "id": "A0A8V0YI39", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YI39", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00104", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00104", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd01327", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01327", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR002350", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002350", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036058", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036058", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YI39", "url": "https://www.orthodb.org/?gene=A0A8V0YI39", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YR89", "url": "https://www.orthodb.org/?gene=A0A8V0YR89", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YW85", "url": "https://www.orthodb.org/?gene=A0A8V0YW85", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21312", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21312", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21312:SF28", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21312:SF28", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00050", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00050", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YI39", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI39", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YI39-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI39-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YR89", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YR89", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YR89-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YR89-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YW85", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YW85", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YW85-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YW85-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTDWVLHHKVGPLDMTTRYIFPLLPLPFLPHSESKRAVCAPRCSAMRTARQFVQVALALCCFADIAFGIEVNCSLYASGIGKDGTSWVACPRNLKPVCGTDGSTYSNECGICLYNREHGANVEKEYDGECRPKHVMIDCSPYLQVVRDGNTMVACPRILKPVCGSDSFTYDNECGICAYNAEHHTNISKLHDGECKLEIGSVDCSKYPSTVSKDGRTLVACPRILSPVCGTDGFTYDNECGICAHNAEQRTHVSKKHDGKCRQEIPEIDCDQYPTRKTTGGKLLVRCPRILLPVCGTDGFTYDNECGICAHNAQHGTEVKKSHDGRCKERSTPLDCTQYLSNTQNGEAITACPFILQEVCGTDGVTYSNDCSLCAHNIELGTSVAKKHDGRCREEVPELDCSKYKTSTLKDGRQVVACTMIYDPVCATNGVTYASECTLCAHNLEQRTNLGKRKNGRCEEDITKEHCREFQKVSPICTMEYVPHCGSDGVTYSNRCFFCNAYVQSNRTLNLVSMAAC", "length": 517, "header": "tr|A0A8V0YI39-1|A0A8V0YI39_CHICK Isoform 1 of Serine peptidase inhibitor, Kazal type 5 OS=Gallus gallus OX=9031 GN=SPINK5 PE=1 SV=1 CANONICAL=A0A8V0YI39-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YI39-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI39/entry#A0A8V0YI39-1", "sequence": { "sequence": "MTDWVLHHKVGPLDMTTRYIFPLLPLPFLPHSESKRAVCAPRCSAMRTARQFVQVALALCCFADIAFGIEVNCSLYASGIGKDGTSWVACPRNLKPVCGTDGSTYSNECGICLYNREHGANVEKEYDGECRPKHVMIDCSPYLQVVRDGNTMVACPRILKPVCGSDSFTYDNECGICAYNAEHHTNISKLHDGECKLEIGSVDCSKYPSTVSKDGRTLVACPRILSPVCGTDGFTYDNECGICAHNAEQRTHVSKKHDGKCRQEIPEIDCDQYPTRKTTGGKLLVRCPRILLPVCGTDGFTYDNECGICAHNAQHGTEVKKSHDGRCKERSTPLDCTQYLSNTQNGEAITACPFILQEVCGTDGVTYSNDCSLCAHNIELGTSVAKKHDGRCREEVPELDCSKYKTSTLKDGRQVVACTMIYDPVCATNGVTYASECTLCAHNLEQRTNLGKRKNGRCEEDITKEHCREFQKVSPICTMEYVPHCGSDGVTYSNRCFFCNAYVQSNRTLNLVSMAAC", "length": 517, "header": "tr|A0A8V0YI39-1|A0A8V0YI39_CHICK Isoform 1 of Serine peptidase inhibitor, Kazal type 5 OS=Gallus gallus OX=9031 GN=SPINK5 PE=1 SV=1 CANONICAL=A0A8V0YI39-1" }, "locus": { "chromosome": "13", "start_pos": 10169415, "end_pos": 10159513, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010035316.1", "url": "https://www.ensembl.org/id/ENSGALT00010035316.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020558.1", "url": "https://www.ensembl.org/id/ENSGALP00010020558.1" } ] } }, { "isoform_ac": "A0A8V0YR89-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI39/entry#A0A8V0YR89-1", "sequence": { "sequence": "MRTARQFVQVALALCCFADIAFGIEVNCSLYASGIGKDGTSWVACPRNLKPVCGTDGSTYSNECGICLYNREHGANVEKEYDGECRPKHVMIDCSPYLQVVRDGNTMVACPRILKPVCGSDSFTYDNECGICAYNAEHHTNISKLHDGECKLEIGSVDCSKYPSTVSKDGRTLVACPRILSPVCGTDGFTYDNECGICAHNAEQRTHVSKKHDGKCRQEIPEVSIQHKVQHGTEVKKSHDGRCKERSTPLDCTQYLSNTQNGEAITACPFILQEVCGTDGVTYSNDCSLCAHNIELGTSVAKKHDGRCREEVPELDCSKYKTSTLKDGRQVVACTMIYDPVCATNGVTYASECTLCAHNLEQRTNLGKRKNGRCEEDITKEHCREFQKVSPICTMEYVPHCGSDGVTYSNRCFFCNAYVQSNRTLNLVSMAAC", "length": 433, "header": "tr|A0A8V0YR89-1|A0A8V0YR89_CHICK Computationally mapped isoform of Serine peptidase inhibitor, Kazal type 5 OS=Gallus gallus OX=9031 GN=SPINK5 PE=1 SV=1 CANONICAL=A0A8V0YI39-1" }, "locus": { "chromosome": "13", "start_pos": 10169415, "end_pos": 10159648, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010035310.1", "url": "https://www.ensembl.org/id/ENSGALT00010035310.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020556.1", "url": "https://www.ensembl.org/id/ENSGALP00010020556.1" } ] } }, { "isoform_ac": "A0A8V0YW85-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI39/entry#A0A8V0YW85-1", "sequence": { "sequence": "MIPQVNCSLYASGIGKDGTSWVACPRNLKPVCGTDGSTYSNECGICLYNREHGANVEKEYDGECRPKHVMIDCSPYLQVVRDGNTMVACPRILKPVCGSDSFTYDNECGICAYNAEHHTNISKLHDGECKLEIGSVDCSKYPSTVSKDGRTLVACPRILSPVCGTDGFTYDNECGICAHNAEQRTHVSKKHDGKCRQEIPEIDCDQYPTRKTTGGKLLVRCPRILLPVCGTDGFTYDNECGICAHNAQHGTEVKKSHDGRCKERSTPLDCTQYLSNTQNGEAITACPFILQEVCGTDGVTYSNDCSLCAHNIELGTSVAKKHDGRCREEVPELDCSKYKTSTLKDGRQVVACTMIYDPVCATNGVTYASECTLCAHNLEQRTNLGKRKNGRCEEDITKEHCREFQKVSPICTMEYVPHCGSDGVTYSNRCFFCNAYVQSNRTLNLVSMAAC", "length": 451, "header": "tr|A0A8V0YW85-1|A0A8V0YW85_CHICK Computationally mapped isoform of Serine peptidase inhibitor, Kazal type 5 OS=Gallus gallus OX=9031 GN=SPINK5 PE=1 SV=1 CANONICAL=A0A8V0YI39-1" }, "locus": { "chromosome": "13", "start_pos": 10169415, "end_pos": 10161190, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010035290.1", "url": "https://www.ensembl.org/id/ENSGALT00010035290.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020549.1", "url": "https://www.ensembl.org/id/ENSGALP00010020549.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "serine-type endopeptidase inhibitor activity", "id": "GO:0004867", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004867", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YI39", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI39" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YI39", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI39" } ], "pmid": "" }, { "name": "protein-containing complex", "id": "GO:0032991", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032991", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YI39", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI39" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "response to steroid hormone", "id": "GO:0048545", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048545", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YI39", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI39" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 186, "end_pos": 188, "annotation": "n_glycosylation_sequon" }, { "start_pos": 506, "end_pos": 508, "annotation": "n_glycosylation_sequon" }, { "start_pos": 72, "end_pos": 74, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YI39", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI39" }, { "id": "PS51465", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51465" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Kazal-like", "eco_id": "ECO_0000259", "start_pos": 67, "end_pos": 132, "start_aa": "Phe", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 186, "end_pos": 188 }, { "start_pos": 506, "end_pos": 508 }, { "start_pos": 72, "end_pos": 74 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YI40-1", "uniprot_ac": "A0A8V0YI40", "uniprot_id": "A0A8V0YI40_CHICK", "mass": { "chemical_mass": 105236.0, "monoisotopic_mass": 105236.0 }, "refseq": {}, "gene_names": [ { "name": "OXR1", "type": "recommended", "evidence": [ { "id": "A0A8V0YI40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI40" } ] } ], "protein_names": [ { "name": "Oxidation resistance protein 1", "type": "recommended", "evidence": [ { "id": "A0A8V0YI40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI40/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "May be involved in protection from oxidative damage.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKS8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKS8#function" }, { "database": "UniProtKB", "id": "ARBA00037112", "url": "https://www.uniprot.org/uniprotkb/ARBA00037112#function" }, { "database": "UniProtKB", "id": "A0A8V0YI40", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI40#function" }, { "database": "UniProtKB", "id": "A0A8V0YIW6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIW6#function" }, { "database": "UniProtKB", "id": "A0A8V0YKT3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKT3#function" }, { "database": "UniProtKB", "id": "A0A8V0YKU6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKU6#function" }, { "database": "UniProtKB", "id": "A0A8V0YKW1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKW1#function" }, { "database": "UniProtKB", "id": "A0A8V0YKW5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKW5#function" }, { "database": "UniProtKB", "id": "A0A8V0YCI8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCI8#function" } ] } ], "disease": [], "snv": [], 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"UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YCI8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCI8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YCI8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCI8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YI40", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI40", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YI40-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI40-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YIW6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIW6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YIW6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIW6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YKS8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKS8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YKS8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKS8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YKT3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKT3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YKT3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKT3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YKU6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKU6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YKU6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKU6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YKW1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKW1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YKW1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKW1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YKW5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKW5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YKW5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKW5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YKX0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKX0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YKX0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKX0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEPLKNTRGKQTRTLSRTLQTRRPKPPPGGCCGSGARRARAGAELRLLRTPRGRAAPELSRGCQQKQLVQSSEFINVNQALLCIMFGTKRLKKKSQSVDISGPGCNPVAAEAPVPQPSKPLLATKTTSEEEQKNTANTQRRNPRRSELKRYYTIDTGQKKTADKKDGRRMSFQKPKGTIEYSVESRDTLNSIALKFDTTPNELVQLNKLFSRAVVPGQILYVPDPDYISSVDSSPSLSPISPLSPTSSEAEFDKATVNDPDGVQQKESVASPAHPCVRTTRVVSSTSEEEEAFTEKFLKINCKYITNGKGTVNGVLLVTPNNIMFDPHKMDPLVQENGCEEYGIMCPMEEVMSAALYKEIMDSKIKDSLSIDVEQLSVRELCHSKKAAKSNTEEMDSRVRDTGNDSASTAPRSTEESLSEDVFTESELSPIREELVSSDELRQDKSSGASSESVQTVNQTSAECLTTILDLKEAGSDLKSCVEMVVNVKQLGTHGIGSEDAEMSVKEGQESSESTENILQQSSQGSHVSEERDKKTPMGKDQDSTQGEEPEIESKMREECPHCESTTDSQKIELTRKRNTEKEQAQDSEAEVEELRKLWKTHTMQQTKQQRENMQQDSQKEISQKTVTSGDGQSEGSSLMKEKRRHRSHKFLCLKVGKPMRKTFVSQASASMQQYAQRDKKHEYWFAVPQERTDHLYVFFIQWSPELYTEDTGDSLREPGFIVVKKKEEPENSEESTTEDAAKEWEITTREDINSKQATNIKTDLEPEAFRPNLSDPSELLQPEQIEKLTKSLPPRTIGYPWTLAYSTAKHGMSLKTLYRTMLGLDTPVLLVIKDSDGQIFGALASEPFKVSDGFYGTGETFLFTFSPDFEVFKWTGDNMFFIKGDMDSLAFGGGGGEFALWLDGDLYHGRSHSCKTFGNHTLSKREDFIIQDIEIWAFE", "length": 940, "header": "tr|A0A8V0YI40-1|A0A8V0YI40_CHICK Isoform 1 of Oxidation resistance protein 1 OS=Gallus gallus OX=9031 GN=OXR1 PE=1 SV=1 CANONICAL=A0A8V0YI40-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YCE5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI40/entry#A0A8V0YCE5-1", "sequence": { "sequence": "MDYLTAFTGKGGRLLRGTASRLWAAVPGGFRQVRFQDSVGYAVPQPAEPAPDTGQKKTADKKDGRRMSFQKPKGTIEYSILYVPDPDYISSVDSSPSLSPISPLSPTSSEAEFDKATVNDPDGVQQKESVASPAHPCVRTTRVVSSTSEEEEAFTEKFLKINCKYITNGKGTVNGVLLVTPNNIMFDPHKMDPLVQENGCEEYGIMCPMEEVMSAALYKEIMDSKIKDSLSIDVEQLSVRELCHSKKAAKSNTEEMDSRVRDTGNDSASTAPRSTEESLSEDVFTESELSPIREELVSSDELRQDKSSGASSESVQTVNQTSAECLTTILDLKEAGSDLKSCVEMVVNVKQLGTHGIGSEDAEMSVKEGQESSESTENILQQSSQGSHVSEERDKKTPMGKDQDSTQGEEPEIESKMREECPHCESTTDSQKIELTRKRNTEKEQAQDSEAEVEELRKLWKTHTMQQTKQQRENMQQDSQKEISQKTVTSGDGQSEGSSLMKEKRRHRSHKFLCLKVGKPMRKTFVSQASASMQQYAQRDKKHEYWFAVPQERTDHLYVFFIQWSPELYTEDTGDSLREPGFIVVKKKEEPENSEESTTEDAAKEWEITTREDINSKQATNIKTDLEPEAFRPNLSDPSELLQPEQIEKLTKSLPPRTIGYPWTLAYSTAKHGMSLKTLYRTMLGLDTPVLLVIKDSDGQIFGALASEPFKVSDGFYGTGETFLFTFSPDFEVFKWTGDNMFFIKGDMDSLAFGGGGGEFALWLDGDLYHGRSHSCKTFGNHTLSKREDFIIQDIEIWAFE", "length": 801, "header": "tr|A0A8V0YCE5-1|A0A8V0YCE5_CHICK Computationally mapped isoform of Oxidation resistance 1 OS=Gallus gallus OX=9031 GN=OXR1 PE=1 SV=1 CANONICAL=A0A8V0YI40-1" }, "locus": { "chromosome": "2", "start_pos": 130578601, "end_pos": 130507767, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031602.1", "url": "https://www.ensembl.org/id/ENSGALT00010031602.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018470.1", "url": "https://www.ensembl.org/id/ENSGALP00010018470.1" } ] } }, { "isoform_ac": "A0A8V0YCI8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI40/entry#A0A8V0YCI8-1", "sequence": { "sequence": "MFGTKRLKKKSQSVDISGPGCNPVAAEAPVPQPSKPLLATKTTSEEEQKNTANTQRRNPRRSELKRYYTIDTGQKKTADKKDGRRMSFQKPKGTIEYSVESRDTLNSIALKFDTTPNELVQLNKLFSRAVVPGQILYVPDPDYISSVDSSPSLSPISPLSPTSSEAEFDKATVNDPDGVQQKESVASPAHPCVRTTRVVSSTSEEEEAFTEKFLKINCKYITNGKGTVNGVLLVTPNNIMFDPHKMDPLVQENGCEEYGIMCPMEEVMSAALYKEIMDSKIKDSLSIDVEQLSVRELCHSKKAAKSNTEEMDSRVRDTGNDSASTAPRSTEESLSEDVFTESELSPIREELVSSDELRQDKSSGASSESVQTVNQTSAECLTTILDLKEAGSDLKSCVEMVVNVKQLGTHGIGSEDAEMSVKEGQESSESTENILQQSSQGSHVSEERDKKTPMGKDQDSTQGEEPEIESKMREECPHCESTTDSQKIELTRKRNTEKEQAQDSEAEVEELRKLWKTHTMQQTKQQRENMQQDSQKEISQKTVTSGDGQSEGSSLMKEKRRHRSHKFLCLKVGKPMRKTFVSQASASMQQYAQRDKKHEYWFAVPQERTDHLYVFFIQWSPELYTEDTGDSLREPGFIVVKKKEEPENSEESTTEDAAKEWEVVSVAEYHRRIDALNSEELRTLCRRLQITTREDINSKQATNIKTDLEPEAFRPNLSDPSELLQPEQIEKLTKSLPPRTIGYPWTLAYSTAKHGMSLKTLYRTMLGLDTPVLLVIKDSDGQIFGALASEPFKVSDGFYGTGETFLFTFSPDFEVFKWTGDNMFFIKGDMDSLAFGGGGGEFALWLDGDLYHGRSHSCKTFGNHTLSKREDFIIQDIEIWAFE", "length": 883, "header": "tr|A0A8V0YCI8-1|A0A8V0YCI8_CHICK Computationally mapped isoform of Oxidation resistance protein 1 OS=Gallus gallus OX=9031 GN=OXR1 PE=1 SV=1 CANONICAL=A0A8V0YI40-1" }, "locus": { "chromosome": "2", "start_pos": 130578601, "end_pos": 130369633, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031653.1", "url": "https://www.ensembl.org/id/ENSGALT00010031653.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018516.1", "url": "https://www.ensembl.org/id/ENSGALP00010018516.1" } ] } }, { "isoform_ac": "A0A8V0YI40-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI40/entry#A0A8V0YI40-1", "sequence": { "sequence": "MEPLKNTRGKQTRTLSRTLQTRRPKPPPGGCCGSGARRARAGAELRLLRTPRGRAAPELSRGCQQKQLVQSSEFINVNQALLCIMFGTKRLKKKSQSVDISGPGCNPVAAEAPVPQPSKPLLATKTTSEEEQKNTANTQRRNPRRSELKRYYTIDTGQKKTADKKDGRRMSFQKPKGTIEYSVESRDTLNSIALKFDTTPNELVQLNKLFSRAVVPGQILYVPDPDYISSVDSSPSLSPISPLSPTSSEAEFDKATVNDPDGVQQKESVASPAHPCVRTTRVVSSTSEEEEAFTEKFLKINCKYITNGKGTVNGVLLVTPNNIMFDPHKMDPLVQENGCEEYGIMCPMEEVMSAALYKEIMDSKIKDSLSIDVEQLSVRELCHSKKAAKSNTEEMDSRVRDTGNDSASTAPRSTEESLSEDVFTESELSPIREELVSSDELRQDKSSGASSESVQTVNQTSAECLTTILDLKEAGSDLKSCVEMVVNVKQLGTHGIGSEDAEMSVKEGQESSESTENILQQSSQGSHVSEERDKKTPMGKDQDSTQGEEPEIESKMREECPHCESTTDSQKIELTRKRNTEKEQAQDSEAEVEELRKLWKTHTMQQTKQQRENMQQDSQKEISQKTVTSGDGQSEGSSLMKEKRRHRSHKFLCLKVGKPMRKTFVSQASASMQQYAQRDKKHEYWFAVPQERTDHLYVFFIQWSPELYTEDTGDSLREPGFIVVKKKEEPENSEESTTEDAAKEWEITTREDINSKQATNIKTDLEPEAFRPNLSDPSELLQPEQIEKLTKSLPPRTIGYPWTLAYSTAKHGMSLKTLYRTMLGLDTPVLLVIKDSDGQIFGALASEPFKVSDGFYGTGETFLFTFSPDFEVFKWTGDNMFFIKGDMDSLAFGGGGGEFALWLDGDLYHGRSHSCKTFGNHTLSKREDFIIQDIEIWAFE", "length": 940, "header": "tr|A0A8V0YI40-1|A0A8V0YI40_CHICK Isoform 1 of Oxidation resistance protein 1 OS=Gallus gallus OX=9031 GN=OXR1 PE=1 SV=1 CANONICAL=A0A8V0YI40-1" }, "locus": { "chromosome": "2", "start_pos": 130578601, "end_pos": 130334535, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031658.1", "url": "https://www.ensembl.org/id/ENSGALT00010031658.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018520.1", "url": "https://www.ensembl.org/id/ENSGALP00010018520.1" } ] } }, { "isoform_ac": "A0A8V0YIW6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI40/entry#A0A8V0YIW6-1", "sequence": { "sequence": "MILQGFTCSSAVMLPGIITRLKKKSQSVDISGPGCNPVAAEAPVPQPSKPLLATKTTSEEEQKNTANTQRRNPRRSELKRYYTIDTGQKKTADKKDGRRMSFQKPKGTIEYSVESRDTLNSIALKFDTTPNELVQLNKLFSRAVVPGQILYVPDPDYISSVDSSPSLSPISPLSPTSSEAEFDKATVNDPDGVQQKESVASPAHPCVRTTRVVSSTSEEEEAFTEKFLKINCKYITNGKGTVNGVLLVTPNNIMFDPHKMDPLVQENGCEEYGIMCPMEEVMSAALYKEIMDSKIKDSLSIDVEQLSVRELCHSKKAAKSNTEEMDSRVRDTGNDSASTAPRSTEESLSEDVFTESELSPIREELVSSDELRQDKSSGASSESVQTVNQTSAECLTTILDLKEAGSDLKSCVEMVVNVKQLGTHGIGSEDAEMSVKEGQESSESTENILQQSSQGSHVSEERDKKTPMGKDQDSTQGEEPEIESKMREECPHCESTTDSQKIELTRKRNTEKEQAQDSEAEVEELRKLWKTHTMQQTKQQRENMQQDSQKEISQKTVTSGDGQSEGSSLMKEKRRHRSHKFLCLKVGKPMRKTFVSQASASMQQYAQRDKKHEYWFAVPQERTDHLYVFFIQWSPELYTEDTGDSLREPGFIVVKKKEEPENSEESTTEDAAKEWEITTREDINSKQATNIKTDLEPEAFRPNLSDPSELLQPEQIEKLTKSLPPRTIGYPWTLAYSTAKHGMSLKTLYRTMLGLDTPVLLVIKDSDGQEAWAHITSYHSGGLKTVNKGFLVR", "length": 793, "header": "tr|A0A8V0YIW6-1|A0A8V0YIW6_CHICK Computationally mapped isoform of Oxidation resistance protein 1 OS=Gallus gallus OX=9031 GN=OXR1 PE=1 SV=1 CANONICAL=A0A8V0YI40-1" }, "locus": { "chromosome": "2", "start_pos": 130577045, "end_pos": 130451907, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031639.1", "url": "https://www.ensembl.org/id/ENSGALT00010031639.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018502.1", "url": "https://www.ensembl.org/id/ENSGALP00010018502.1" } ] } }, { "isoform_ac": "A0A8V0YKS8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI40/entry#A0A8V0YKS8-1", "sequence": { "sequence": "MEAGPNPEVSPSCEAGPAAERSCVCGLAVVPAAVGSPSAMDYLTAFTGKGGRLLRGTASRLWAAVPGGFRQVRFQDSVGYAVPQPAEPAPDTGQKKTADKKDGRRMSFQKPKGTIEYSVESRDTLNSIALKFDTTPNELVQLNKLFSRAVVPGQILYVPDPDYISSVDSSPSLSPISPLSPTSSEAEFDKATVNDPDGVQQKESVASPAHPCVRTTRVVSSTSEEEEAFTEKFLKINCKYITNGKGTVNGVLLVTPNNIMFDPHKMDPLVQENGCEEYGIMCPMEEVMSAALYKEIMDSKIKDSLSIDVEQLSVRELCHSKKAAKSNTEEMDSRVRDTGNDSASTAPRSTEESLSEDVFTESELSPIREELVSSDELRQDKSSGASSESVQTVNQTSAECLTTILDLKEAGSDLKSCVEMVVNVKQLGTHGIGSEDAEMSVKEGQESSESTENILQQSSQGSHVSEERDKKTPMGKDQDSTQGEEPEIESKMREECPHCESTTDSQKIELTRKRNTEKEQAQDSEAEVEELRKLWKTHTMQQTKQQRENMQQDSQKEISQKTVTSGDGQSEGSSLMKEKRRHRSHKFLCLKVGKPMRKTFVSQASASMQQYAQRDKKHEYWFAVPQERTDHLYVFFIQWSPELYTEDTGDSLREPGFIVVKKKEEPENSEESTTEDAAKEWEITTREDINSKQATNIKTDLEPEAFRPNLSDPSELLQPEQIEKLTKSLPPRTIGYPWTLAYSTAKHGMSLKTLYRTMLGLDTPVLLVIKDSDGQIFGALASEPFKVSDGFYGTGETFLFTFSPDFEVFKWTGDNMFFIKGDMDSLAFGGGGGEFALWLDGDLYHGRSHSCKTFGNHTLSKREDFIIQDIEIWAFE", "length": 876, "header": "tr|A0A8V0YKS8-1|A0A8V0YKS8_CHICK Computationally mapped isoform of Oxidation resistance protein 1 OS=Gallus gallus OX=9031 GN=OXR1 PE=1 SV=1 CANONICAL=A0A8V0YI40-1" }, "locus": { "chromosome": "2", "start_pos": 130578601, "end_pos": 130507650, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031606.1", "url": "https://www.ensembl.org/id/ENSGALT00010031606.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018473.1", "url": "https://www.ensembl.org/id/ENSGALP00010018473.1" } ] } }, { "isoform_ac": "A0A8V0YKT3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI40/entry#A0A8V0YKT3-1", "sequence": { "sequence": "MLLKREDLTRKKKQNFLPLRSTYSFLCFIQKNISGMSCTDSYGSGKDTGQKKTADKKDGRRMSFQKPKGTIEYSVESRDTLNSIALKFDTTPNELVQLNKLFSRAVVPGQILYVPDPDYISSVDSSPSLSPISPLSPTSSEAEFDKATVNDPDGVQQKESVASPAHPCVRTTRVVSSTSEEEEAFTEKFLKINCKYITNGKGTVNGVLLVTPNNIMFDPHKMDPLVQENGCEEYGIMCPMEEVMSAALYKEIMDSKIKDSLSIDVEQLSVRELCHSKKAAKSNTEEMDSRVRDTGNDSASTAPRSTEESLSEDVFTESELSPIREELVSSDELRQDKSSGASSESVQTVNQTSAECLTTILDLKEAGSDLKSCVEMVVNVKQLGTHGIGSEDAEMSVKEGQESSESTENILQQSSQGSHVSEERDKKTPMGKDQDSTQGEEPEIESKMREECPHCESTTDSQKIELTRKRNTEKEQAQDSEAEVEELRKLWKTHTMQQTKQQRENMQQDSQKEISQKTVTSGDGQSEGSSLMKEKRRHRSHKFLCLKVGKPMRKTFVSQASASMQQYAQRDKKHEYWFAVPQERTDHLYVFFIQWSPELYTEDTGDSLREPGFIVVKKKEEPENSEESTTEDAAKEWEITTREDINSKQATNIKTDLEPEAFRPNLSDPSELLQPEQIEKLTKSLPPRTIGYPWTLAYSTAKHGMSLKTLYRTMLGLDTPVLLVIKDSDGQIFGALASEPFKVSDGFYGTGETFLFTFSPDFEVFKWTGDNMFFIKGDMDSLAFGGGGGEFALWLDGDLYHGRSHSCKTFGNHTLSKREDFIIQDIEIWAFE", "length": 832, "header": "tr|A0A8V0YKT3-1|A0A8V0YKT3_CHICK Computationally mapped isoform of Oxidation resistance protein 1 OS=Gallus gallus OX=9031 GN=OXR1 PE=1 SV=1 CANONICAL=A0A8V0YI40-1" }, "locus": { "chromosome": "2", "start_pos": 130578601, "end_pos": 130501290, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031611.1", "url": "https://www.ensembl.org/id/ENSGALT00010031611.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018478.1", "url": "https://www.ensembl.org/id/ENSGALP00010018478.1" } ] } }, { "isoform_ac": "A0A8V0YKU6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI40/entry#A0A8V0YKU6-1", "sequence": { "sequence": "MDLRKNLIAYTGQKKTADKKDGRRMSFQKPKGTIEYSVESRDTLNSIALKFDTTPNELVQLNKLFSRAVVPGQILYVPDPDYISSVDSSPSLSPISPLSPTSSEAEFDKATVNDPDGVQQKESVASPAHPCVRTTRVVSSTSEEEEAFTEKFLKINCKYITNGKGTVNGVLLVTPNNIMFDPHKMDPLVQENGCEEYGIMCPMEEVMSAALYKEIMDSKIKDSLSIDVEQLSVRELCHSKKAAKSNTEEMDSRVRDTGNDSASTAPRSTEESLSEDVFTESELSPIREELVSSDELRQDKSSGASSESVQTVNQTSAECLTTILDLKEAGSDLKSCVEMVVNVKQLGTHGIGSEDAEMSVKEGQESSESTENILQQSSQGSHVSEERDKKTPMGKDQDSTQGEEPEIESKMREECPHCESTTDSQKIELTRKRNTEKEQAQDSEAEVEELRKLWKTHTMQQTKQQRENMQQDSQKEISQKTVTSGDGQSEGSSLMKEKRRHRSHKFLCLKVGKPMRKTFVSQASASMQQYAQRDKKHEYWFAVPQERTDHLYVFFIQWSPELYTEDTGDSLREPGFIVVKKKEEPENSEESTTEDAAKEWEITTREDINSKQATNIKTDLEPEAFRPNLSDPSELLQPEQIEKLTKSLPPRTIGYPWTLAYSTAKHGMSLKTLYRTMLGLDTPVLLVIKDSDGQIFGALASEPFKVSDGFYGTGETFLFTFSPDFEVFKWTGDNMFFIKGDMDSLAFGGGGGEFALWLDGDLYHGRSHSCKTFGNHTLSKREDFIIQDIEIWAFE", "length": 795, "header": "tr|A0A8V0YKU6-1|A0A8V0YKU6_CHICK Computationally mapped isoform of Oxidation resistance protein 1 OS=Gallus gallus OX=9031 GN=OXR1 PE=1 SV=1 CANONICAL=A0A8V0YI40-1" }, "locus": { "chromosome": "2", "start_pos": 130578601, "end_pos": 130461465, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031627.1", "url": "https://www.ensembl.org/id/ENSGALT00010031627.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018493.1", "url": "https://www.ensembl.org/id/ENSGALP00010018493.1" } ] } }, { "isoform_ac": "A0A8V0YKW1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI40/entry#A0A8V0YKW1-1", "sequence": { "sequence": "MQPALFFFLCLDWSCNNNGQQKQLVQSSEFINVNQALLCIMFGTKRLKKKSQSVDISGPGCNPVAAEAPVPQPSKPLLATKTTSEEEQKNTANTQRRNPRRSELKRYYTIDTGQKKTADKKDGRRMSFQKPKGTIEYSVESRDTLNSIALKFDTTPNELVQLNKLFSRAVVPGQILYVPDPDYISSVDSSPSLSPISPLSPTSSEAEFDKATVNDPDGVQQKESVASPAHPCVRTTRVVSSTSEEEEAFTEKFLKINCKYITNGKGTVNGVLLVTPNNIMFDPHKMDPLVQENGCEEYGIMCPMEEVMSAALYKEIMDSKIKDSLSIDVEQLSVRELCHSKKAAKSNTEEMDSRVRDTGNDSASTAPRSTEESLSEDVFTESELSPIREELVSSDELRQDKSSGASSESVQTVNQTSAECLTTILDLKEAGSDLKSCVEMVVNVKQLGTHGIGSEDAEMSVKEGQESSESTENILQQSSQGSHVSEERDKKTPMGKDQDSTQGEEPEIESKMREECPHCESTTDSQKIELTRKRNTEKEQAQDSEAEVEELRKLWKTHTMQQTKQQRENMQQDSQKEISQKTVTSGDGQSEGSSLMKEKRRHRSHKFLCLKVGKPMRKTFVSQASASMQQYAQRDKKHEYWFAVPQERTDHLYVFFIQWSPELYTEDTGDSLREPGFIVVKKKEEPENSEESTTEDAAKEWEITTREDINSKQATNIKTDLEPEAFRPNLSDPSELLQPEQIEKLTKSLPPRTIGYPWTLAYSTAKHGMSLKTLYRTMLGLDTPVLLVIKDSDGQIFGALASEPFKVSDGFYGTGETFLFTFSPDFEVFKWTGDNMFFIKGDMDSLAFGGGGGEFALWLDGDLYHGRSHSCKTFGNHTLSKREDFIIQDIEIWAFE", "length": 896, "header": "tr|A0A8V0YKW1-1|A0A8V0YKW1_CHICK Computationally mapped isoform of Oxidation resistance protein 1 OS=Gallus gallus OX=9031 GN=OXR1 PE=1 SV=1 CANONICAL=A0A8V0YI40-1" }, "locus": { "chromosome": "2", "start_pos": 130578601, "end_pos": 130336551, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031645.1", "url": "https://www.ensembl.org/id/ENSGALT00010031645.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018509.1", "url": "https://www.ensembl.org/id/ENSGALP00010018509.1" } ] } }, { "isoform_ac": "A0A8V0YKW5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI40/entry#A0A8V0YKW5-1", "sequence": { "sequence": "MILQGFTCSSAVMLPGIITRLKKKSQSVDISGPGCNPVAAEAPVPQPSKPLLATKTTSEEEQKNTANTQRRNPRRSELKRYYTIDTGQKKTADKKDGRRMSFQKPKGTIEYSVESRDTLNSIALKFDTTPNELVQLNKLFSRAVVPGQILYVPDPDYISSVDSSPSLSPISPLSPTSSEAEFDKATVNDPDGVQQKESVASPAHPCVRTTRVVSSTSEEEEAFTEKFLKINCKYITNGKGTVNGVLLVTPNNIMFDPHKMDPLVQENGCEEYGIMCPMEEVMSAALYKEIMDSKIKDSLSIDVEQLSVRELCHSKKAAKSNTEEMDSRVRDTGNDSASTAPRSTEESLSEDVFTESELSPIREELVSSDELRQDKSSGASSESVQTVNQTSAECLTTILDLKEAGSDLKSCVEMVVNVKQLGTHGIGSEDAEMSVKEGQESSESTENILQQSSQGSHVSEERDKKTPMGKDQDSTQGEEPEIESKMREECPHCESTTDSQKIELTRKRNTEKEQAQDSEAEVEELRKLWKTHTMQQTKQQRENMQQDSQKEISQKTVTSGDGQSEGSSLMKEKRRHRSHKFLCLKVGKPMRKTFVSQASASMQQYAQRDKKHEYWFAVPQERTDHLYVFFIQWSPELYTEDTGDSLREPGFIVVKKKEEPENSEESTTEDAAKEWEVVSVAEYHRRIDALNSEELRTLCRRLQITTREDINSKQATNIKTDLEPEAFRPNLSDPSELLQPEQIEKLTKSLPPRTIGYPWTLAYSTAKHGMSLKTLYRTMLGLDTPVLLVIKDSDGQIFGALASEPFKVSDGFYGTGETFLFTFSPDFEVFKWTGDNMFFIKGDMDSLAFGGGGGEFALWLDGDLYHGRSHSCKTFGNHTLSKREDFIIQDIEIWAFE", "length": 897, "header": "tr|A0A8V0YKW5-1|A0A8V0YKW5_CHICK Computationally mapped isoform of Oxidation resistance protein 1 OS=Gallus gallus OX=9031 GN=OXR1 PE=1 SV=1 CANONICAL=A0A8V0YI40-1" }, "locus": { "chromosome": "2", "start_pos": 130578601, "end_pos": 130451907, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031651.1", "url": "https://www.ensembl.org/id/ENSGALT00010031651.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018514.1", "url": "https://www.ensembl.org/id/ENSGALP00010018514.1" } ] } }, { "isoform_ac": "A0A8V0YKX0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI40/entry#A0A8V0YKX0-1", "sequence": { "sequence": "MFGTKRLKKKSQSVDISGPGCNPVAAEAPVPQPSKPLLATKTTSEEEQKNTANTQRRNPRRSELKRYYTIDTGQKKTADKKDGRRMSFQKPKGTIEYSDPDGVQQKESVASPAHPCVRTTRVVSSTSEEEEAFTEKFLKINCKYITNGKGTVNGVLLVTPNNIMFDPHKMDPLVQENGCEEYGIMCPMEEVMSAALYKEIMDSKIKDSLSIDVEQLSVRELCHSKKAAKSNTEEMDSRVRDTGNDSASTAPRSTEESLSEDVFTESELSPIREELVSSDELRQDKSSGASSESVQTVNQTSAECLTTILDLKEAGSDLKSCVEMVVNVKQLGTHGIGSEDAEMSVKEGQESSESTENILQQSSQGSHVSEERDKKTPMGKDQDSTQGEEPEIESKMREECPHCESTTDSQKIELTRKRNTEKEQAQDSEAEVEELRKLWKTHTMQQTKQQRENMQQDSQKEISQKTVTSGDGQSEGSSLMKEKRRHRSHKFLCLKVGKPMRKTFVSQASASMQQYAQRDKKHEYWFAVPQERTDHLYVFFIQWSPELYTEDTGDSLREPGFIVVKKKEEPENSEESTTEDAAKEWEITTREDINSKQATNIKTDLEPEAFRPNLSDPSELLQPEQIEKLTKSLPPRTIGYPWTLAYSTAKHGMSLKTLYRTMLGLDTPVLLVIKDSDGQIFGALASEPFKVSDGFYGTGETFLFTFSPDFEVFKWTGDNMFFIKGDMDSLAFGGGGGEFALWLDGDLYHGRSHSCKTFGNHTLSKREDFIIQDIEIWAFE", "length": 780, "header": "tr|A0A8V0YKX0-1|A0A8V0YKX0_CHICK Computationally mapped isoform of Oxidation resistance 1 OS=Gallus gallus OX=9031 GN=OXR1 PE=1 SV=1 CANONICAL=A0A8V0YI40-1" }, "locus": { "chromosome": "2", "start_pos": 130578601, "end_pos": 130369633, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031657.1", "url": "https://www.ensembl.org/id/ENSGALT00010031657.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018519.1", "url": "https://www.ensembl.org/id/ENSGALP00010018519.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A480JWV7-1", "protein_name": "Oxidation resistance protein 1", "gene_name": "OXR1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSVSNLSWLKKKSQSVDITAPGFNPLAGAGKQMPQASKPPAPKTPIIEEEQNNAANSQKHPSRRSELKRFYTIDTGQKKTLDKKDGRRMSFQKPKGTIEYTVESRDSLNSIALKFDTTPNELVQLNKLFTRAVVTGQVLYVPDPEYVSSVESSPSLSPISPLSPTSSEAEFDKTTTPDVIHPKEATPSSTFTGIRPARVVSSTSEEEEAFTEKFLKINCRYITSGKGTVSGVLLVTPNNIMFDPHKTDPLVQENGCEEYGIMCPMEEVMSAAMYKEILDSKIKESLPIEIDHLSGRDFCHLKKVTRSNTDEIDSRMRDAGNDSASTAPRSTEESFSEDVFTESELSPIREELVSSDELRQDKSSGASSESVQTITQSGTEALMVIAEAASAPDHLKSDSGHITNEVETHSLKTDSNNLEMATKEGDHSADNFQEMSLPKEQTTSIQDNADRDFLLTENSLHQEEGEKESMPCGEATAFKQKQIVSKGKQGKEQNQDSETEVEELRKLWKTHTMQQTKQQRENIQQVSQKEIKHKIATADIEGSVLLKEKRRHRLHKFLCLRVGKPMRKTFVSQASATMQQYAQRDKKHEYWFAVPQERTDHLYAFFIQWSPEIYAEDTGECSREPGFIVVKKIEESEISEDSTNEAAAREWEVVSVAEYHRRIDALNTEELRTLCRRLQITTREDINSKQVAPAKADLESESFRPNLSDPSELLLLDQIEKLTKHLPPRTIGYPWTLVYGTGKHGTSLKTLYRTMTGLDTPVLMVIKDSDGQVFGALASEPFKVSDGFYGTGETFVFTFCPEFEVFKWTGDNMFFIKGDMDSLAFGGGGGEFALWLDGDLYHGRSHSCKTFGNRTLSKKEDFFIQDIEIWAFE", "length": 873 }, "evidence": [ { "id": "A0A8V0YI40", "url": "https://omabrowser.org/oma/group/A0A8V0YI40/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "I3ISS4-1", "protein_name": "Oxidation resistance protein 1B", "gene_name": "oxr1b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MFSTKRLKKKSQSVDIPDEGYAGSLVKDLLASPLIKNVARTTIREEKEINTTNIQKARSPRRGELKRGYTIDTGQKKSALERKDVRRISFQRPKGTMEYVVESRDTLNSIALKFDTTPNELVQLNKLFSRAVVPGKVLYVPDPEYISSAESSPSLSPISPLSPTSSEADLEKATKGLDHVHRRHSSSTGLAHGPPRPARVVSSTSEEEEALTEKFLKMNCKYITDGKGIVSGVLLVTPNNIMFDPHKSDRLVQERGCEEYGIMCPLEEVQSAAMCREITDVRLREFVPPDLELEPSVSEVSHLKRAPRLNAADAAHRIRETGNDSASTAPRSTEASLSEDVFTESELSPVRDDALATSSDELQQIKSSGASSESVQTINQAATVTEDQSSAGGTDVKEAGQIEGVGWRDSGIEQSLNTTDVFNEESCENVLENVQRDQSGDEPKSRTTSESLCSDTVAVEDAVKETQKSLEDQSLQASSDVKEGELRTDSDSTAAVEPGAEEGLKSAEEVVPGLRGKQKSKLHKFLCLRVGRAMRKTFVSHASASMQQYAQRDRKHEYWFAVPSERSDHLFGFFVQWTPDVYGEGFGGLTREPGFVVVKKNQDAESGEQDKPVPDITFKDWEVVSVAEYYRRIDALNSEDLRSLCKRLQITTKEEVNSKLMVKSDPEPETFRPNLTEPSVLLQPEHIEKLAKHLPPRTIGYPWSLAFSTSKHGMSMKSLYRAMQSQDSPVLMVIKDSDGQMFGALASQPFKVSDGFYGTGETFVFTFYPEFEVFKWTGDNMFFIKGDMDSLAVGGGGGEFGLWLDGDLYHGRTHSCKTFGNPMLSKTEDFFVQDIEIWAFE", "length": 841 }, "evidence": [ { "id": "A0A8V0YI40", "url": "https://omabrowser.org/oma/group/A0A8V0YI40/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q4KMM3-1", "protein_name": "Oxidation resistance protein 1", "gene_name": "Oxr1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSVSNLSWLKKKSQSVDITAPGFNPLGGAGKQAPQASKPPAPKTPIIEEEQNNSANTQKHPSRKSELKRFYTIDTGQKKTLDKKDGRRMSFQKPKGTIEYTVESRDSLNSIALKFDTTPNELVQLNKLFSRAVVTGQVLYVPDPEYVSSVESSPSLSPVSPLSPTSSEAEFDKTTTPDVAHPKEAPPASTVSGIRPARVVSSTSEEEEAFTEKFLKINCKYITIGKGTVSGVLLVTPNNIMFDPHKTDPLVQENGCEEYGIMCPMEEVMSAAMYKEILDSKIKESLPIELDQLSGRGSCHSKKATGVSAEDADPRARDQGNDSASTAPRSTEESLSEDAFTESELSPIREELLSSEPRQEKSSDASSESVQTVSQMEVQSLTATSEAANVPDRTSSNPGALSHETGLSGLETATKGGDKATESLQEVSGPKEQSTEVKGQDNQDSSHQESSLQQEAGEDSVSSGETVELKEKPAVLKDQQGQELKRDSETEVEELRKLWKTHSMQQAKQQRDTIQQVSQRESKHSSAAADAHGEGSSLLKEKRRHRLHKFLCLRVGKPMRKTFVSQASATMQQYAQRDKKHEYWFAVPQERTDHLYAFFIQWSPEIYAEDSGEYTREPGFIVVKKMDESEANEAPAGEAAAREWEVVSVAEYHRRIDALNTEELRTLCRRLQITTREDINSKQVAPAKADLEPESFRPNLSDPSELLLPDQIEKLTKHLPPRTIGYPWTLVYGTGKHGTSLKTLYRTMTGLDTPVLMVIKDSDGQVFGALASEPFKVSDGFYGTGETFVFTFCPEFEVFKWTGDNMFFIKGDMDSLAFGGGGGEFALWLDGDLYHGRSHSCKTFGNHTLSKKEDFFIQDIEIWAFE", "length": 866 }, "evidence": [ { "id": "A0A8V0YI40", "url": "https://omabrowser.org/oma/group/A0A8V0YI40/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q4V8B0-1", "protein_name": "Oxidation resistance protein 1", "gene_name": "Oxr1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDYLTTFTGKSGRLLRGTASRLWGLGGGGEARQVRFEDYLREPAPGDPGCGPGELRPPSPTSPEGPDTGQKKTLDKKDGRRMSFQKPKGTIEYTVESRDSLNSIALKFDTTPNELVQLNKLFSRAVVTGQVLYVPDPEYVSSVESSPSLSPVSPLSPTSSEAEFDKTTTPDVVHPKEAPPSSTESSIRPARVVSSTSEEEEAFTEKFLKINCKYITNGKGTVSGVLLVTPNNIMFDPHKTDPLVQENGCEEYGIMCPMEEVMSAAMYKEILDSKLKESLPIEVDQLSGRGFCHSKKMTGVPAEETDSRSRDQGNDSVSTAPRSTEESLSEDVFTESELSPIREELPSSELRQEKSSDASSESVQTVSQIEVESLTAASESADVPDHTNANSGRSSSEVGALSHETGLSSLEIATKEGDKATGNLQEVSGPKEQSTDIKGQDNQDSFHHENSLQQEAGEDSLSSGETVELTEKPTVLKDQQGKELKRDSETEVEELRKLWKTHSMQQAKQQRDTIQQVAQRESKHRGAPADAHGEGSSLLKEKRRHRLHKFLCLRVGKPMRKTFVSQASATMQQYAQRDKKHEYWFAVPQERTDHLYAFFIQWSPEIYAEDTGEYTREPGFIVVKKMAESGPDEAPAGEAAAREWEITTREDINSKQAAPAKADLEPESFRPNLSDPSELLLPDQIEKLTKHLPPRTIGYPWTLVYGTGKHGTSLKTLYRTMTGLDTPVLMVIKDSDGQVFGALASEPFKVSDGFYGTGETFVFTFCPEFEVFKWTGDNMFFIKGDMDSLAFGGGGGEFALWLDGDLYHGRSHSCKTFGNHTLSKKEDFFIQDIEIWAFE", "length": 839 }, "evidence": [ { "id": "A0A8V0YI40", "url": "https://omabrowser.org/oma/group/A0A8V0YI40/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8N573-1", "protein_name": "Oxidation resistance protein 1", "gene_name": "OXR1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTKDKNSPGLKKKSQSVDINAPGFNPLAGAGKQTPQASKPPAPKTPIIEEEQNNAANTQKHPSRRSELKRFYTIDTGQKKTLDKKDGRRMSFQKPKGTIEYTVESRDSLNSIALKFDTTPNELVQLNKLFSRAVVTGQVLYVPDPEYVSSVESSPSLSPVSPLSPTSSEAEFDKTTNPDVHPTEATPSSTFTGIRPARVVSSTSEEEEAFTEKFLKINCKYITSGKGTVSGVLLVTPNNIMFDPHKNDPLVQENGCEEYGIMCPMEEVMSAAMYKEILDSKIKESLPIDIDQLSGRDFCHSKKMTGSNTEEIDSRIRDAGNDSASTAPRSTEESLSEDVFTESELSPIREELVSSDELRQDKSSGASSESVQTVNQAEVESLTVKSESTGTPGHLRSDTEHSTNEVGTLCHKTDLNNLEMAIKEDQIADNFQGISGPKEDSTSIKGNSDQDSFLHENSLHQEESQKENMPCGETAEFKQKQSVNKGKQGKEQNQDSQTEAEELRKLWKTHTMQQTKQQRENIQQVSQKEAKHKITSADGHIESSALLKEKQRHRLHKFLCLRVGKPMRKTFVSQASATMQQYAQRDKKHEYWFAVPQERTDHLYAFFIQWSPEIYAEDTGEYTREPGFIVVKKIEESETIEDSSNQAAAREWEVVSVAEYHRRIDALNTEELRTLCRRLQITTREDINSKQVATVKADLESESFRPNLSDPSELLLPDQIEKLTKHLPPRTIGYPWTLVYGTGKHGTSLKTLYRTMTGLDTPVLMVIKDSDGQVFGALASEPLKVSDGFYGTGETFVFTFCPEFEVFKWTGDNMFFIKGDMDSLAFGGGGGEFALWLDGDLYHGRSHSCKTFGNRTLSKKEDFFIQDIEIWAFE", "length": 874 }, "evidence": [ { "id": "A0A8V0YI40", "url": "https://omabrowser.org/oma/group/A0A8V0YI40/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YI40", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI40" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YI40", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI40" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YI40", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI40" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "response to oxidative stress", "id": "GO:0006979", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006979", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YI40", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI40" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "oxidoreductase activity", "id": "GO:0016491", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016491", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YI40", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI40" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 404, "end_pos": 406, "annotation": "n_glycosylation_sequon" }, { "start_pos": 458, "end_pos": 460, "annotation": "n_glycosylation_sequon" }, { "start_pos": 773, "end_pos": 775, "annotation": "n_glycosylation_sequon" }, { "start_pos": 920, "end_pos": 922, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YI40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI40" }, { "id": "PS51782", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51782" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "LysM", "eco_id": "ECO_0000259", "start_pos": 179, "end_pos": 222, "start_aa": "Ile", "end_aa": "Val", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0YI40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI40" }, { "id": "PS51886", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51886" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "TLDc", "eco_id": "ECO_0000259", "start_pos": 779, "end_pos": 940, "start_aa": "Glu", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 404, "end_pos": 406 }, { "start_pos": 458, "end_pos": 460 }, { "start_pos": 773, "end_pos": 775 }, { "start_pos": 920, "end_pos": 922 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, 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Classification" ] }, { "id": "PTHR14958", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14958", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14958:SF24", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14958:SF24", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02214", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02214", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YI56", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI56", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YI56-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI56-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YI74", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI74", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YI74-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI74-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YPJ9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPJ9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YPJ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPJ9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YPK0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPK0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YPK0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPK0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YPL2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPL2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YPL2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPL2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YRB8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRB8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YRB8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRB8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YRC8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRC8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YRC8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRC8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPGGMRMWMEGGEEMKGAVGLRCGWDPPPIDAQAKWVRLNVGGTVFLTTRQTLCREQKSFLCRLCQGEELQSDRDETGAYLIDRDPTYFGPILNFLRHGKLVLDKDMAEEGVLEEAEFYNIGPLIRIIKDRLEEKDYTVAQVPPKHVYRVLQCQEEELTQMVSTMSDGWRFEQLVNIGSYYNYGNEDQTEFLCVVSKELYNSPNGLSSESSHKAKTVHVPDTPSCSPPSPSLHCHLPGTPYPIPQPPAFSPLFSLPLMASFQQTWFPSPLPNARFCLLPAQGPISLYSSLFLLCRYVTYLHSQILPV", "length": 307, "header": "tr|A0A8V0YI56-1|A0A8V0YI56_CHICK Isoform 1 of Potassium channel tetramerization domain containing 17 OS=Gallus gallus OX=9031 GN=KCTD17 PE=4 SV=1 CANONICAL=A0A8V0YI56-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YI56-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI56/entry#A0A8V0YI56-1", "sequence": { "sequence": "MPGGMRMWMEGGEEMKGAVGLRCGWDPPPIDAQAKWVRLNVGGTVFLTTRQTLCREQKSFLCRLCQGEELQSDRDETGAYLIDRDPTYFGPILNFLRHGKLVLDKDMAEEGVLEEAEFYNIGPLIRIIKDRLEEKDYTVAQVPPKHVYRVLQCQEEELTQMVSTMSDGWRFEQLVNIGSYYNYGNEDQTEFLCVVSKELYNSPNGLSSESSHKAKTVHVPDTPSCSPPSPSLHCHLPGTPYPIPQPPAFSPLFSLPLMASFQQTWFPSPLPNARFCLLPAQGPISLYSSLFLLCRYVTYLHSQILPV", "length": 307, "header": "tr|A0A8V0YI56-1|A0A8V0YI56_CHICK Isoform 1 of Potassium channel tetramerization domain containing 17 OS=Gallus gallus OX=9031 GN=KCTD17 PE=4 SV=1 CANONICAL=A0A8V0YI56-1" }, "locus": { "chromosome": "1", "start_pos": 51540729, "end_pos": 51535121, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010035360.1", "url": "https://www.ensembl.org/id/ENSGALT00010035360.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020578.1", "url": "https://www.ensembl.org/id/ENSGALP00010020578.1" } ] } }, { "isoform_ac": "A0A8V0YI74-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI56/entry#A0A8V0YI74-1", "sequence": { "sequence": "MFCDDKKGEIFNQKKRENEEKTRNDETGAYLIDRDPTYFGPILNFLRHGKLVLDKDMAEEGVLEEAEFYNIGPLIRIIKDRLEEKDYTVAQVPPKHVYRVLQCQEEELTQMVSTMSDGWRFEQLVNIGSYYNYGNEDQTEFLCVVSKELYNSPNGLSSESSHKAKLVDHLPLQSSCSSCSLAGES", "length": 185, "header": "tr|A0A8V0YI74-1|A0A8V0YI74_CHICK Computationally mapped isoform of Potassium channel tetramerization domain containing 17 OS=Gallus gallus OX=9031 GN=KCTD17 PE=4 SV=1 CANONICAL=A0A8V0YI56-1" }, "locus": { "chromosome": "1", "start_pos": 51542141, "end_pos": 51527625, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010035392.1", "url": "https://www.ensembl.org/id/ENSGALT00010035392.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020598.1", "url": "https://www.ensembl.org/id/ENSGALP00010020598.1" } ] } }, { "isoform_ac": "A0A8V0YPJ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI56/entry#A0A8V0YPJ9-1", "sequence": { "sequence": "MEGGEEMKGAVGLRCGWDPPPIDAQAKWVRLNVGGTVFLTTRQTLCREQKSFLCRLCQGEELQSDRDETGAYLIDRDPTYFGPILNFLRHGKLVLDKDMAEEGVLEEAEFYNIGPLIRIIKDRLEEKDYTVAQVPPKHVYRVLQCQEEELTQMVSTMSDGWRFEQLVNIGSYYNYGNEDQTEFLCVVSKELYNSPNGLSSESSHKAKQELLWLIWQVSPLFLPFVLHAGLQSTEEDVEEEEQEMEEEAEAEAEEKGAANP", "length": 260, "header": "tr|A0A8V0YPJ9-1|A0A8V0YPJ9_CHICK Computationally mapped isoform of Potassium channel tetramerization domain containing 17 OS=Gallus gallus OX=9031 GN=KCTD17 PE=4 SV=1 CANONICAL=A0A8V0YI56-1" }, "locus": { "chromosome": "1", "start_pos": 51540705, "end_pos": 51535617, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010035366.1", "url": "https://www.ensembl.org/id/ENSGALT00010035366.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020582.1", "url": "https://www.ensembl.org/id/ENSGALP00010020582.1" } ] } }, { "isoform_ac": "A0A8V0YPK0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI56/entry#A0A8V0YPK0-1", "sequence": { "sequence": "MEGGEEMKGAVGLRCGWDPPPIDAQAKWVRLNVGGTVFLTTRQTLCREQKSFLCRLCQGEELQSDRDETGAYLIDRDPTYFGPILNFLRHGKLVLDKDMAEEGVLEEAEFYNIGPLIRIIKDRLEEKDYTVAQVPPKHVYRVLQCQEEELTQMVSTMSDGWRFEQLVNIGSYYNYGNEDQTEFLCVVSKELYNSPNGLSSESSHKAKSTEEDVEEEEQEMEEEAEAEAEEKGAANP", "length": 236, "header": "tr|A0A8V0YPK0-1|A0A8V0YPK0_CHICK Computationally mapped isoform of Potassium channel tetramerization domain containing 17 OS=Gallus gallus OX=9031 GN=KCTD17 PE=4 SV=1 CANONICAL=A0A8V0YI56-1" }, "locus": { "chromosome": "1", "start_pos": 51540705, "end_pos": 51535617, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010035352.1", "url": "https://www.ensembl.org/id/ENSGALT00010035352.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020575.1", "url": "https://www.ensembl.org/id/ENSGALP00010020575.1" } ] } }, { "isoform_ac": "A0A8V0YPL2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI56/entry#A0A8V0YPL2-1", "sequence": { "sequence": "MIKKERFLTKRKERMKKRQEITSCRSKIPFPEESLHMLARRQLSAHFPARTAWQLMQHCAVSLGQTLCREQKSFLCRLCQGEELQSDRDETGAYLIDRDPTYFGPILNFLRHGKLVLDKDMAEEGVLEEAEFYNIGPLIRIIKDRLEEKDYTVAQVPPKHVYRVLQCQEEELTQMVSTMSDGWRFEQLVNIGSYYNYGNEDQTEFLCVVSKELYNSPNGLSSESSHKAKVRPTSLWPFSYCL", "length": 242, "header": "tr|A0A8V0YPL2-1|A0A8V0YPL2_CHICK Computationally mapped isoform of Potassium channel tetramerization domain containing 17 OS=Gallus gallus OX=9031 GN=KCTD17 PE=4 SV=1 CANONICAL=A0A8V0YI56-1" }, "locus": { "chromosome": "1", "start_pos": 51542131, "end_pos": 51536391, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010035381.1", "url": "https://www.ensembl.org/id/ENSGALT00010035381.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020592.1", "url": "https://www.ensembl.org/id/ENSGALP00010020592.1" } ] } }, { "isoform_ac": "A0A8V0YRB8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI56/entry#A0A8V0YRB8-1", "sequence": { "sequence": "MFCDDKKGEIFNQKKRENEEKTRNTLCREQKSFLCRLCQGEELQSDRDETGAYLIDRDPTYFGPILNFLRHGKLVLDKDMAEEGVLEEAEFYNIGPLIRIIKDRLEEKDYTVAQVPPKHVYRVLQCQEEELTQMVSTMSDGWRFEQLVNIGSYYNYGNEDQTEFLCVVSKELYNSPNGLSSESSHKAKLLQARGLRM", "length": 197, "header": "tr|A0A8V0YRB8-1|A0A8V0YRB8_CHICK Computationally mapped isoform of Potassium channel tetramerization domain containing 17 OS=Gallus gallus OX=9031 GN=KCTD17 PE=4 SV=1 CANONICAL=A0A8V0YI56-1" }, "locus": { "chromosome": "1", "start_pos": 51542141, "end_pos": 51534220, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010035372.1", "url": "https://www.ensembl.org/id/ENSGALT00010035372.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020586.1", "url": "https://www.ensembl.org/id/ENSGALP00010020586.1" } ] } }, { "isoform_ac": "A0A8V0YRC8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI56/entry#A0A8V0YRC8-1", "sequence": { "sequence": "MKGAVGLRCGWDPPPIDAQAKWVRLNVGGTVFLTTRQTLCREQKSFLCRLCQGEELQSDRDETGAYLIDRDPTYFGPILNFLRHGKLVLDKDMAEEGVLEEAEFYNIGPLIRIIKDRLEEKDYTVAQVPPKHVYRVLQCQEEELTQMVSTMSDGWRFEQLVNIGSYYNYGNEDQTEFLCVVSKELYNSPNGLSSESSHKAKLVDHLPLQSSCSSCSLAGES", "length": 221, "header": "tr|A0A8V0YRC8-1|A0A8V0YRC8_CHICK Computationally mapped isoform of Potassium channel tetramerization domain containing 17 OS=Gallus gallus OX=9031 GN=KCTD17 PE=4 SV=1 CANONICAL=A0A8V0YI56-1" }, "locus": { "chromosome": "1", "start_pos": 51540687, "end_pos": 51527625, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010035387.1", "url": "https://www.ensembl.org/id/ENSGALT00010035387.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020596.1", "url": "https://www.ensembl.org/id/ENSGALP00010020596.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YI56", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI56" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YI56", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI56" } ], "pmid": "" }, { "name": "Cul3-RING ubiquitin ligase complex", "id": "GO:0031463", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031463", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YI56", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI56" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YI56", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI56" } ], "pmid": "" }, { "name": "cullin family protein binding", "id": "GO:0097602", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097602", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YI56", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI56" } ], "pmid": "" }, { "name": "ubiquitin-like ligase-substrate adaptor activity", "id": "GO:1990756", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990756", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YI56", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI56" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "protein homooligomerization", "id": "GO:0051260", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051260", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YI56", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI56" } ], "pmid": "" }, { "name": "proteasome-mediated ubiquitin-dependent protein catabolic process", "id": "GO:0043161", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043161", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YI56", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI56" } ], "pmid": "" }, { "name": "endoplasmic reticulum calcium ion homeostasis", "id": "GO:0032469", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032469", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YI56", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI56" } ], "pmid": "" }, { "name": "positive regulation of cilium assembly", "id": "GO:0045724", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045724", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YI56", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI56" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YI56", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI56" }, { "id": "SM00225", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00225" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "BTB", "eco_id": "ECO_0000259", "start_pos": 35, "end_pos": 136, "start_aa": "Lys", "end_aa": "Asp", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YI60-1", "uniprot_ac": "A0A8V0YI60", "uniprot_id": "A0A8V0YI60_CHICK", "mass": { "chemical_mass": 99951.0, "monoisotopic_mass": 99951.0 }, "refseq": {}, "gene_names": [ { "name": "PWP2", "type": "recommended", "evidence": [ { "id": "A0A8V0YI60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI60" } ] } ], "protein_names": [ { "name": "PWP2 small subunit processome component", "type": "synonym", "evidence": [ { "id": "A0A8V0YI60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI60/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YWC1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YWC1#function" }, { "database": "UniProtKB", "id": "ARBA00035000", "url": "https://www.uniprot.org/uniprotkb/ARBA00035000#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YI60", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI60" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PWP2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI60", "locus": { "chromosome": "1", "start_pos": 110410967, "end_pos": 110393893, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010014726", "url": "https://www.ensembl.org/id/ENSGALG00010014726" } ] } } ], "crossref": [ { "id": "A0A8V0YI60", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YI60", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00200", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00200", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001680", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001680", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007148", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007148", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011047", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011047", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019775", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019775", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020472", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020472", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027145", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027145", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036322", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036322", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056153", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056153", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YI60", "url": "https://www.orthodb.org/?gene=A0A8V0YI60", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YWC1", "url": "https://www.orthodb.org/?gene=A0A8V0YWC1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR19858", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19858", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19858:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19858:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00400", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00400", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF04003", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04003", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23381", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23381", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-6791226", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6791226", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YI60", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI60", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YI60-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI60-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YWC1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YWC1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YWC1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YWC1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKFAYRFSGLLGTVYRRGNLNFTRDGSCLISPVGNRISLFDLKNNKCETFPLATRHNIVCVGLSPDGSLAILVDEALPAILLVFLHDRRFVITKDNVALMYHAPGKKREFNAFVLDKTYYGPYDETTCIDWTDDSKCFAIGSKDMSTWVFGAERWANLIYYSLGGHKDVIVACFFEENSLDLYTVSRDGALCVWQCDTELDDLKPMPPKEARQKNRVKDDDGFLEEPKGEEIHGKANPNEQEMREKVKYTRVAKYFFNKEGDFNNLTSAAYHKKTHLLVTGFASGIFHLHELPDFNLIHSLSISDQRIASISINSTGDWIAFGCSGLGQLLVWEWQSESYVLKQQGHFNSMVSLAYSPDGQYIVTGGEDGKVKVWNTSSSFCFVTFTDHSSGVTAVTFTSSGYVILSASLDGTVRAFDLHRYRNFRTFTSPRPSQFSCLAVDSSGEIVSAGSQDSFEIFIWSMQSGRLLDVLSGHEGPISSLSFNPMKCVLASGSWDKTVKLWDMLDSWRTKETLMLNSDVLVVAFRPDGKELAVASLNGQITFWDHENAVQVGSIEGRHDLQMGRKELDKITAKQSAKGKSFTTLCYSADGQSILAGGLSKFVCIYNVKEQILMKKFEISCNFSLDAMEEYLDRRKMTEFGSMALIDEGTGDEDGVAIPLPGVKRGDMSSRHFKPEIRVTCLRFSPTGRSWAATTTEGLLIYSLDAGLIFDPFELDIDVTPSNIRKKLHQKEYTVAIVMALKLNEKKLIQEVIEAIPGNEVDVVCSSLPDLYVEKVLEFLASAFEISCHLEFYLIWAHKLLMLHGQKLKTRSQKLLPVIQFLQKSIQRHFEDVSKLCEWNIYNIKYALAISQQRGVKRVAETSVDEEDLESDSDYLMQEVHNDNFSS", "length": 888, "header": "tr|A0A8V0YI60-1|A0A8V0YI60_CHICK Isoform 1 of PWP2 small subunit processome component OS=Gallus gallus OX=9031 GN=PWP2 PE=1 SV=1 CANONICAL=A0A8V0YI60-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YI60-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI60/entry#A0A8V0YI60-1", "sequence": { "sequence": "MKFAYRFSGLLGTVYRRGNLNFTRDGSCLISPVGNRISLFDLKNNKCETFPLATRHNIVCVGLSPDGSLAILVDEALPAILLVFLHDRRFVITKDNVALMYHAPGKKREFNAFVLDKTYYGPYDETTCIDWTDDSKCFAIGSKDMSTWVFGAERWANLIYYSLGGHKDVIVACFFEENSLDLYTVSRDGALCVWQCDTELDDLKPMPPKEARQKNRVKDDDGFLEEPKGEEIHGKANPNEQEMREKVKYTRVAKYFFNKEGDFNNLTSAAYHKKTHLLVTGFASGIFHLHELPDFNLIHSLSISDQRIASISINSTGDWIAFGCSGLGQLLVWEWQSESYVLKQQGHFNSMVSLAYSPDGQYIVTGGEDGKVKVWNTSSSFCFVTFTDHSSGVTAVTFTSSGYVILSASLDGTVRAFDLHRYRNFRTFTSPRPSQFSCLAVDSSGEIVSAGSQDSFEIFIWSMQSGRLLDVLSGHEGPISSLSFNPMKCVLASGSWDKTVKLWDMLDSWRTKETLMLNSDVLVVAFRPDGKELAVASLNGQITFWDHENAVQVGSIEGRHDLQMGRKELDKITAKQSAKGKSFTTLCYSADGQSILAGGLSKFVCIYNVKEQILMKKFEISCNFSLDAMEEYLDRRKMTEFGSMALIDEGTGDEDGVAIPLPGVKRGDMSSRHFKPEIRVTCLRFSPTGRSWAATTTEGLLIYSLDAGLIFDPFELDIDVTPSNIRKKLHQKEYTVAIVMALKLNEKKLIQEVIEAIPGNEVDVVCSSLPDLYVEKVLEFLASAFEISCHLEFYLIWAHKLLMLHGQKLKTRSQKLLPVIQFLQKSIQRHFEDVSKLCEWNIYNIKYALAISQQRGVKRVAETSVDEEDLESDSDYLMQEVHNDNFSS", "length": 888, "header": "tr|A0A8V0YI60-1|A0A8V0YI60_CHICK Isoform 1 of PWP2 small subunit processome component OS=Gallus gallus OX=9031 GN=PWP2 PE=1 SV=1 CANONICAL=A0A8V0YI60-1" }, "locus": { "chromosome": "1", "start_pos": 110410166, "end_pos": 110393958, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010035367.1", "url": "https://www.ensembl.org/id/ENSGALT00010035367.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020583.1", "url": "https://www.ensembl.org/id/ENSGALP00010020583.1" } ] } }, { "isoform_ac": "A0A8V0YWC1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI60/entry#A0A8V0YWC1-1", "sequence": { "sequence": "MKFAYRFSGLLGTVYRRGNLNFTRDGSCLISPVGNRISLFDLKNNKCETFPLATRHNIVCVGLSPDGSLAILVDEEGAALLVSVIGKSVIHQFHFHKPVHSVSFSPDGKRFVITKDNVALMYHAPGKKREFNAFVLDKTYYGPYDETTCIDWTDDSKCFAIGSKDMSTWVFGAERWANLIYYSLGGHKDVIVACFFEENSLDLYTVSRDGALCVWQCDTELDDLKPMPPKEARQKNRVKDDDGFLEEPKGEEIHGKANPNEQEMREKVKYTRVAKYFFNKEGDFNNLTSAAYHKKTHLLVTGFASGIFHLHELPDFNLIHSLSISDQRIASISINSTGDWIAFGCSGLGQLLVWEWQSESYVLKQQGHFNSMVSLAYSPDGQYIVTGGEDGKVKVWNTSSSFCFVTFTDHSSGVTAVTFTSSGYVILSASLDGTVRAFDLHRYRNFRTFTSPRPSQFSCLAVDSSGEIVSAGSQDSFEIFIWSMQSGRLLDVLSGHEGPISSLSFNPMKCVLASGSWDKTVKLWDMLDSWRTKETLMLNSDVLVVAFRPDGKELAVASLNGQITFWDHENAVQVGSIEGRHDLQMGRKELDKITAKQSAKGKSFTTLCYSADGQSILAGGLSKFVCIYNVKEQILMKKFEISCNFSLDAMEEYLDRRKMTEFGSMALIDEGTGDEDGVAIPLPGGLLIYSLDAGLIFDPFELDIDVTPSNIRKKLHQKEYTVAIVMALKLNEKKLIQEVIEAIPGNEVDVVCSSLPDLYVEKVLEFLASAFEISCHLEFYLIWAHKLLMLHGQKLKTRSQKLLPVIQFLQKSIQRHFEDVSKLYVLLYFKV", "length": 831, "header": "tr|A0A8V0YWC1-1|A0A8V0YWC1_CHICK Computationally mapped isoform of Periodic tryptophan protein 2 homolog OS=Gallus gallus OX=9031 GN=PWP2 PE=1 SV=1 CANONICAL=A0A8V0YI60-1" }, "locus": { "chromosome": "1", "start_pos": 110409866, "end_pos": 110393958, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010035377.1", "url": "https://www.ensembl.org/id/ENSGALT00010035377.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020589.1", "url": "https://www.ensembl.org/id/ENSGALP00010020589.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-6791226", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6791226", "resource": "Reactome", "description": "Major pathway of rRNA processing in the nucleolus and cytosol" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "Pwp2p-containing subcomplex of 90S preribosome", "id": "GO:0034388", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034388", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YI60", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI60" } ], "pmid": "" }, { "name": "small-subunit processome", "id": "GO:0032040", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032040", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YI60", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI60" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YI60", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI60" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "id": "GO:0000462", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000462", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YI60", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI60" } ], "pmid": "" }, { "name": "ribosomal small subunit assembly", "id": "GO:0000028", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000028", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YI60", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI60" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 21, "end_pos": 23, "annotation": "n_glycosylation_sequon" }, { "start_pos": 265, "end_pos": 267, "annotation": "n_glycosylation_sequon" }, { "start_pos": 314, "end_pos": 316, "annotation": "n_glycosylation_sequon" }, { "start_pos": 376, "end_pos": 378, "annotation": "n_glycosylation_sequon" }, { "start_pos": 623, "end_pos": 625, "annotation": "n_glycosylation_sequon" }, { "start_pos": 885, "end_pos": 887, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YI60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI60" }, { "id": "PF23381", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23381" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "IFT122/SMU1 beta-propeller", "eco_id": "ECO_0000259", "start_pos": 308, "end_pos": 559, "start_aa": "Ile", "end_aa": "Arg", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0YI60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI60" }, { "id": "PF04003", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04003" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Small-subunit processome Utp12", "eco_id": "ECO_0000259", "start_pos": 745, "end_pos": 849, "start_aa": "Asn", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 21, "end_pos": 23 }, { "start_pos": 265, "end_pos": 267 }, { "start_pos": 314, "end_pos": 316 }, { "start_pos": 376, "end_pos": 378 }, { "start_pos": 623, "end_pos": 625 }, { "start_pos": 885, "end_pos": 887 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YI70-1", "uniprot_ac": "A0A8V0YI70", "uniprot_id": "A0A8V0YI70_CHICK", "mass": { "chemical_mass": 59417.0, "monoisotopic_mass": 59417.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Reverse transcriptase domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A8V0YI70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI70/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YI70", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI70" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI70", "locus": {} } ], "crossref": [ { "id": "A0A8V0YI70", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YI70", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd01650", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01650", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000477", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000477", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043502", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043502", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR33332", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR33332", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00078", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00078", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YI70", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI70", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YI70-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI70-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MISRDVGLAKSGVRTLNFGRANFKLFNGLLAKIPWDAILKDKNVEDSWLLFKDALLKAEEVSIPLNKKVGRRDRKPARLSKDLLGTMRAKKGAYKLWKQGPVIWEEYRDAVRTCRRRIRKAKAQVELNLARDVKNNKKTLYRYTGQKRQAKMGVPSLLNLKGELAEKAEVLNEFFALVFTGGQDSSLSHAPEPCTPKPLGGTRGINPPPTLRAEKVRDRLMRLGEYKSLGPDGVHPRVLKELAEVDAELLSIIFEKSWLSGEVPDDWRKGYVTPIYKKGSKEDPGNYRPVSLTSVPGKIMEQILLDDMLDHMRSEHVIRDSQHGFTRGRSCLTNLVAFYDGVTALVDEGKATDVIYLDLTKAFDMVSHHILISKLEGCGFDGWTTRWTRNWLKGHRQSVVINGAMSRWWPVTSGVPQGSVLGLVLFNIFINDTDDRIECTLSKFADDTKLSGAVDTEEGRDAIQRDVDRLERWAWVNLMRFNMAKCKVLTWAGGTPGIYTDWKEQSLRAALQRRTWGSSLMTNLT", "length": 525, "header": "tr|A0A8V0YI70-1|A0A8V0YI70_CHICK Isoform 1 of Reverse transcriptase domain-containing protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0YI70-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YI70-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI70/entry#A0A8V0YI70-1", "sequence": { "sequence": "MISRDVGLAKSGVRTLNFGRANFKLFNGLLAKIPWDAILKDKNVEDSWLLFKDALLKAEEVSIPLNKKVGRRDRKPARLSKDLLGTMRAKKGAYKLWKQGPVIWEEYRDAVRTCRRRIRKAKAQVELNLARDVKNNKKTLYRYTGQKRQAKMGVPSLLNLKGELAEKAEVLNEFFALVFTGGQDSSLSHAPEPCTPKPLGGTRGINPPPTLRAEKVRDRLMRLGEYKSLGPDGVHPRVLKELAEVDAELLSIIFEKSWLSGEVPDDWRKGYVTPIYKKGSKEDPGNYRPVSLTSVPGKIMEQILLDDMLDHMRSEHVIRDSQHGFTRGRSCLTNLVAFYDGVTALVDEGKATDVIYLDLTKAFDMVSHHILISKLEGCGFDGWTTRWTRNWLKGHRQSVVINGAMSRWWPVTSGVPQGSVLGLVLFNIFINDTDDRIECTLSKFADDTKLSGAVDTEEGRDAIQRDVDRLERWAWVNLMRFNMAKCKVLTWAGGTPGIYTDWKEQSLRAALQRRTWGSSLMTNLT", "length": 525, "header": "tr|A0A8V0YI70-1|A0A8V0YI70_CHICK Isoform 1 of Reverse transcriptase domain-containing protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0YI70-1" }, "locus": { "chromosome": "2", "start_pos": 122199722, "end_pos": 122198148, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031697.1", "url": "https://www.ensembl.org/id/ENSGALT00010031697.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018545.1", "url": "https://www.ensembl.org/id/ENSGALP00010018545.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 495, "start_aa": "Thr", "end_pos": 495, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr495", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 431, "end_pos": 433, "annotation": "n_glycosylation_sequon" }, { "start_pos": 523, "end_pos": 525, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YI70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI70" }, { "id": "PS50878", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50878" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Reverse transcriptase", "eco_id": "ECO_0000259", "start_pos": 256, "end_pos": 496, "start_aa": "Lys", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 495 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 431, "end_pos": 433 }, { "start_pos": 523, "end_pos": 525 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YI90-1", "uniprot_ac": "A0A8V0YI90", "uniprot_id": "A0A8V0YI90_CHICK", "mass": { "chemical_mass": 37299.0, "monoisotopic_mass": 37299.0 }, "refseq": {}, "gene_names": [ { "name": "STX16", "type": "recommended", "evidence": [ { "id": "A0A8V0YI90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI90" } ] } ], "protein_names": [ { "name": "Syntaxin-16", "type": "recommended", "evidence": 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"https://www.uniprot.org/uniprotkb/A0A8V0YI90" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "STX16", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI90", "locus": { "chromosome": "20", "start_pos": 11416731, "end_pos": 11433886, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010014735", "url": "https://www.ensembl.org/id/ENSGALG00010014735" } ] } } ], "crossref": [ { "id": "A0A8V0YI90", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YI90", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15845", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15845", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "419315", "url": "https://www.ncbi.nlm.nih.gov/gene/419315", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000727", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000727", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006012", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006012", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR010989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045242", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045242", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YI90", "url": "https://www.orthodb.org/?gene=A0A8V0YI90", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YRD3", "url": "https://www.orthodb.org/?gene=A0A8V0YRD3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YRD7", "url": "https://www.orthodb.org/?gene=A0A8V0YRD7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR19957", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19957", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19957:SF83", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19957:SF83", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05739", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05739", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-6811438", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6811438", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-6811440", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6811440", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YI90", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI90", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YI90-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI90-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YRD3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRD3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YRD3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRD3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YRD7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRD7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YRD7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRD7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLTHEALIHGVEIHRFGDMALLESQSWSCILAQANPGTSAPLLLKELDELADDRMALVSGISLDPEAAIGVTKRLPPKWVDGADEIQYDIVRVKQKMKELASLHDKHLNRPTLDDSSEEERAIEITTQEITQLFHRCQRAVQVLQSRSRTCTEQEARVLRNVVSSLAQSLQELSTNFRHAQSDYLKRMKSREERSKHFFDTSVPLMDDGEDDTLYDRGFTDDQLALVEQNTLLVEEREREIRQIVQSISDLNEIFRDLGAMIVEQGTVLDRIDYNVEQSCIKTEEGLKQLHKAEQYQKKNRKMLVILILFVIVIVLIVVLIGVKSH", "length": 326, "header": "tr|A0A8V0YI90-1|A0A8V0YI90_CHICK Isoform 1 of Syntaxin-16 OS=Gallus gallus OX=9031 GN=STX16 PE=1 SV=1 CANONICAL=A0A8V0YI90-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YI90-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI90/entry#A0A8V0YI90-1", "sequence": { "sequence": "MLTHEALIHGVEIHRFGDMALLESQSWSCILAQANPGTSAPLLLKELDELADDRMALVSGISLDPEAAIGVTKRLPPKWVDGADEIQYDIVRVKQKMKELASLHDKHLNRPTLDDSSEEERAIEITTQEITQLFHRCQRAVQVLQSRSRTCTEQEARVLRNVVSSLAQSLQELSTNFRHAQSDYLKRMKSREERSKHFFDTSVPLMDDGEDDTLYDRGFTDDQLALVEQNTLLVEEREREIRQIVQSISDLNEIFRDLGAMIVEQGTVLDRIDYNVEQSCIKTEEGLKQLHKAEQYQKKNRKMLVILILFVIVIVLIVVLIGVKSH", "length": 326, "header": "tr|A0A8V0YI90-1|A0A8V0YI90_CHICK Isoform 1 of Syntaxin-16 OS=Gallus gallus OX=9031 GN=STX16 PE=1 SV=1 CANONICAL=A0A8V0YI90-1" }, "locus": { "chromosome": "20", "start_pos": 11433687, "end_pos": 11418655, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010035417.1", "url": "https://www.ensembl.org/id/ENSGALT00010035417.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020613.1", "url": "https://www.ensembl.org/id/ENSGALP00010020613.1" } ] } }, { "isoform_ac": "A0A8V0YRD3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI90/entry#A0A8V0YRD3-1", "sequence": { "sequence": "MATRRLTDAFLLLRNNAVQSRQLLAEQVSSYGSSSPLNSRSMAAALADDRMALVSGISLDPEAAIGVTKRLPPKWVDGADEIQYDIVRVKQKMKELASLHDKHLNRPTLDDSSEEERAIEITTQEITQLFHRCQRAVQVLQSRSRTCTEQEARVLRNVVSSLAQSLQELSTNFRHAQSDYLKRMKSREERSKHFFDTSVPLMDDGEDDTLYDRGFTDDQLALVEQNTLLVEEREREIRQIVQSISDLNEIFRDLGAMIVEQGTVLDRIDYNVEQSCIKTEEGLKQLHKVIISIAWVARIIFNIFSYHITFVES", "length": 313, "header": "tr|A0A8V0YRD3-1|A0A8V0YRD3_CHICK Computationally mapped isoform of Syntaxin-16 OS=Gallus gallus OX=9031 GN=STX16 PE=1 SV=1 CANONICAL=A0A8V0YI90-1" }, "locus": { "chromosome": "20", "start_pos": 11427038, "end_pos": 11420401, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010035398.1", "url": "https://www.ensembl.org/id/ENSGALT00010035398.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020601.1", "url": "https://www.ensembl.org/id/ENSGALP00010020601.1" } ] } }, { "isoform_ac": "A0A8V0YRD7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI90/entry#A0A8V0YRD7-1", "sequence": { "sequence": "MATRRLTDAFLLLRNNAVQSRQLLAEQLADDRMALVSGISLDPEAAIGVTKRLPPKWVDGADEIQYDIVRVKQKMKELASLHDKHLNRPTLDDSSEEERAIEITTQEITQLFHRCQRAVQVLQSRSRTCTEQEARVLRNVVSSLAQSLQELSTNFRHAQSDYLKRMKSREERSKHFFDTSVPLMDDGEDDTLYDRGFTDDQLALVEQNTLLVEEREREIRQIVQSISDLNEIFRDLGAMIVEQGTVLDRIDYNVEQSCIKTEEGLKQLHKAEQYQKKNRKMLVILILFVIVIVLIVVLIGVKSH", "length": 304, "header": "tr|A0A8V0YRD7-1|A0A8V0YRD7_CHICK Computationally mapped isoform of Syntaxin-16 OS=Gallus gallus OX=9031 GN=STX16 PE=1 SV=1 CANONICAL=A0A8V0YI90-1" }, "locus": { "chromosome": "20", "start_pos": 11427038, "end_pos": 11418655, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010035405.1", "url": "https://www.ensembl.org/id/ENSGALT00010035405.1" }, { "database": "Ensembl Peptide", "id": 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"table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YI94-1", "uniprot_ac": "A0A8V0YI94", "uniprot_id": "A0A8V0YI94_CHICK", "mass": { "chemical_mass": 261250.0, "monoisotopic_mass": 261250.0 }, "refseq": { "ac": "NP_001366043", "name": "bromodomain and WD repeat-containing protein 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001366043" }, "gene_names": [ { "name": "BRWD1", "type": "recommended", "evidence": [ { "id": "A0A8V0YI94", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI94" } ] }, { "name": "BRWD1", "type": "synonym", "evidence": [ { "id": "NP_001366043", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001366043" } ] }, { "name": "WDR9", "type": "synonym", "evidence": [ { "id": "NP_001366043", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001366043" } ] } ], "protein_names": [ { "name": "Bromodomain and WD repeat-containing protein 1", "type": "recommended", "evidence": [ { "id": "A0A8V0YI94", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI94/entry#names_and_taxonomy" } ] }, { "name": "WD repeat domain 9", "type": "synonym", "evidence": [ { "id": "NP_001366043", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001366043" } ] }, { "name": "WD repeat-containing protein 9", "type": "synonym", "evidence": [ { "id": "A0A8V0YI94", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI94/entry#names_and_taxonomy" } ] }, { "name": "bromodomain and WD repeat-containing protein 1", "type": "synonym", "evidence": [ { "id": "NP_001366043", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001366043" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## RNAseq introns :: mixed sample support SAMEA103992290, SAMEA103992323 [ECO:0006172] ##Evidence-Data-END## INFERRED REFSEQ: This record is predicted by genome sequence analysis and is not yet supported by experimental evidence. The reference sequence was derived from JAENSK010000020.1. On Sep 23, 2021 this sequence version replaced NP_001366043.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001366043", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001366043" } ] }, { "annotation": "May be a transcriptional activator. May be involved in chromatin remodeling. Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the control of cell shape.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YI94", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI94#function" }, { "database": "UniProtKB", "id": "ARBA00053491", "url": "https://www.uniprot.org/uniprotkb/ARBA00053491#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YI94", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI94" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "BRWD1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI94", "locus": { "chromosome": "1", "start_pos": 108024055, "end_pos": 108075575, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010014738", "url": "https://www.ensembl.org/id/ENSGALG00010014738" } ] } } ], "crossref": [ { "id": "cd00200", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00200", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd05496", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05496", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd05529", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05529", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "418521", "url": "https://www.ncbi.nlm.nih.gov/gene/418521", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001487", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001487", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001680", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001680", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018359", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018359", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019775", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019775", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036322", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036322", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036427", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036427", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052060", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052060", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057451", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057451", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "QDCTHIS", "url": "https://omabrowser.org/oma/group/QDCTHIS/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YI94", "url": "https://www.orthodb.org/?gene=A0A8V0YI94", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16266", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16266", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16266:SF26", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16266:SF26", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00400", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00400", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00439", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00439", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25313", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25313", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25437", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25437", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-1266695", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1266695", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-3247509", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3247509", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001366043", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001366043", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YI94", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI94", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YI94-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI94-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAESSASFGSGASPPLIESELYFLIARFLSTGPCRGTLRVLVQELEQHQLLPKRLDWEGNEHYRSYEELVLSNKHVAPDHLLQICKRIGPILDKEIPPSISRVNSLLGAGRQSLLRTAKDCRNTVWKGSAFAALHRGRPPEFPVNYGTPPNLVEVYRARQLTGYAKFSTSFPGSMYQHVKMHRRILGHLSSVYCVAFDRTGHRIFTGSDDCLVKIWSTHNGRLFATLRGHSAEISDMAVNYENTMIAAGSCDKMIRVWCLRTCAPVAVLHGHTGSITSLQFSPMVKGSLRYMVSTGADGNVCFWQWDTDSMKFSNRPVKFTEKPRPGVQMLCSSFSVGGMFLATGSTDHVIRMYYFGSETPERIAELESHADKVDSIQFSNSGDRFISGSRDGTARIWRFEEAEWRSILLDMSDRLPGDMCSDEDKFMRPKVTMIAWNQDDNYVVTAVNNHLLKVWNSSTGQLLHDLVGHADEVFVLETHPFDSRIMLSAGHDGNIFIWDITKGTKTKHYFNMIEGQGHGAVFDCKFSPDGQHFACTDSHGHLLIFGFGCSKPYEKIPDQMFFHTDYRPLIRDSNNYVLDEQTQQAPHLMPPPFLVDVDGNPHPTKYQRLVPGRENSADEHLIPQLGYVATSDGEVVEQVIGQQTVDQDEQGMEPSILDGMIRQLQLQQDQRNAAADQEPASSGLQNGEGTPRRVFRRPSLDIQSPPNIGLRRSGQVEGVRQMHQNAPRSQMATERDLQAWRRRVVVPEIPPSLLRKQEKYRIAKGEEERDLYQSEKRRKSFQSSEKSDSETSIIQSKRRLHRRKYPNYRTRNNIEQLDSSDEERDDCFGLMEQEAEESEGSGSSEEEEEWRSDKKSNTFSSSDSSSRYSDWIADAGINLQPPVRTSRRKAVRYCSTSEDEVSAGKSSPPKRRRRKRRKKPRPKKQEGANTPTQPVNSELSYDWHPPVWITDTALRRSPFVPQMGDEVIYFRQGHEAYIEAVRRNNIYELNPHKEPWRKVVLRDQELVKIVGIRYEVGPPTLCCLKLAFIDHATGKHTDKSFSIKYHDMPDVIDFLILRQFYDEARQRNWQASDRFRSIIDDAWWFGTVLGQEPYQPQYPDSHFQCYSVKWDNGEVEKLSPWDMEPISDNVDQPEELGASVSVTFEEMEKLLYKPEEGEWGMRSRDEACERIISGIDQLLTLDISAAFAGPVDLCTYPKYCTVIAYPTDLNTIRTRLANRFYRRISALVWEVRYIESNARTFNEPGSAIARAAKKITTQLLKFINDQDCTNIFDLCSTTDDEQDCLDADDLDDEKCRPRTSYRRRKGRGKRGKSMKNGYDENCWKKQCMELVNLIFQCEDSEPFRQPVDLDQYPDYRHIIDTPMDFGTVKETLEAGNYDTPMELCKDIRLIFSNAKSYTPNKKSKIYSMTLRLSALFEEKIRRIVSDFKNGQKQNEKIRRNQRYTRRVQSQSSAQHPTKMPSRNLKQKPLKSQAKIESEQEDSFSQPTSSRAACVASHKTNASNYNHSSSGESSDSACLASFERNGKARSTTLTNRSTLSSAESEVEGSLASSTPSSSSTEESSEESKESSVALVSPPLHNGICRRKNINCRITRNQAAQRKQIGTLPQENGNTRKAVRKRLYESDSENTSAVTSESLSNSTGRHRKIPRRSATVAATKLRLMSDVEEEVSSSESIGIGCKNRKLPHRNASAAARRMLLEGSEDDAGLKSESEKETEEQLTKRKVLSLSTSSAVRRKFVSESENESSDSETDTQMKQKTWQSNGHRQLRGTALSASPEMRSPTRGFSEEDSKSHNSEDGSSQKAEQSMSANKFVVSNSEDEACSESDRWNARKLFGLHLVAPIKKAKVLSDLEDTAESETEDRQDGRSVVSETLVPCRITASPNSGPGADFNDSCDTESETNSNNSNYFDASSKTKKRKRKGKTKIFRKESTSEEPGQSGKVLRSRTCIINYRKHIKVSNVTEKKNPRRCATLAANKIKIMSDTKEELSSSESVCTVKKNRRQLHGSASGASKKKPISSSDIDVSVMSENEKEQDSDGKNDFCSGSSAPKRKYISESEDEKTESEVEIEVTKKENDNDSQTKRTESDAALKNTFDSSEENSTNHKVENGRNWRTSGQSTSAYNHHVSNSEEEVSSELAKRETKTIRRARNKRSRAPLKRLKLSNDLKETSESAAGRKIEEKSSVSENVETPGTAGSSKANLNCSSDSDSGTDNSIYSDATETKKRKTDIVRKEISNLPKTSRRPQRRKRRKPKQENDSEDLEYTKYRRANRRTKIRTRNRGRRTVRYDDCDDDDDDRGVGDAACET", "length": 2306, "header": "tr|A0A8V0YI94-1|A0A8V0YI94_CHICK Isoform 1 of Bromodomain and WD repeat-containing protein 1 OS=Gallus gallus OX=9031 GN=BRWD1 PE=4 SV=1 CANONICAL=A0A8V0YI94-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YI94-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI94/entry#A0A8V0YI94-1", "sequence": { "sequence": "MAESSASFGSGASPPLIESELYFLIARFLSTGPCRGTLRVLVQELEQHQLLPKRLDWEGNEHYRSYEELVLSNKHVAPDHLLQICKRIGPILDKEIPPSISRVNSLLGAGRQSLLRTAKDCRNTVWKGSAFAALHRGRPPEFPVNYGTPPNLVEVYRARQLTGYAKFSTSFPGSMYQHVKMHRRILGHLSSVYCVAFDRTGHRIFTGSDDCLVKIWSTHNGRLFATLRGHSAEISDMAVNYENTMIAAGSCDKMIRVWCLRTCAPVAVLHGHTGSITSLQFSPMVKGSLRYMVSTGADGNVCFWQWDTDSMKFSNRPVKFTEKPRPGVQMLCSSFSVGGMFLATGSTDHVIRMYYFGSETPERIAELESHADKVDSIQFSNSGDRFISGSRDGTARIWRFEEAEWRSILLDMSDRLPGDMCSDEDKFMRPKVTMIAWNQDDNYVVTAVNNHLLKVWNSSTGQLLHDLVGHADEVFVLETHPFDSRIMLSAGHDGNIFIWDITKGTKTKHYFNMIEGQGHGAVFDCKFSPDGQHFACTDSHGHLLIFGFGCSKPYEKIPDQMFFHTDYRPLIRDSNNYVLDEQTQQAPHLMPPPFLVDVDGNPHPTKYQRLVPGRENSADEHLIPQLGYVATSDGEVVEQVIGQQTVDQDEQGMEPSILDGMIRQLQLQQDQRNAAADQEPASSGLQNGEGTPRRVFRRPSLDIQSPPNIGLRRSGQVEGVRQMHQNAPRSQMATERDLQAWRRRVVVPEIPPSLLRKQEKYRIAKGEEERDLYQSEKRRKSFQSSEKSDSETSIIQSKRRLHRRKYPNYRTRNNIEQLDSSDEERDDCFGLMEQEAEESEGSGSSEEEEEWRSDKKSNTFSSSDSSSRYSDWIADAGINLQPPVRTSRRKAVRYCSTSEDEVSAGKSSPPKRRRRKRRKKPRPKKQEGANTPTQPVNSELSYDWHPPVWITDTALRRSPFVPQMGDEVIYFRQGHEAYIEAVRRNNIYELNPHKEPWRKVVLRDQELVKIVGIRYEVGPPTLCCLKLAFIDHATGKHTDKSFSIKYHDMPDVIDFLILRQFYDEARQRNWQASDRFRSIIDDAWWFGTVLGQEPYQPQYPDSHFQCYSVKWDNGEVEKLSPWDMEPISDNVDQPEELGASVSVTFEEMEKLLYKPEEGEWGMRSRDEACERIISGIDQLLTLDISAAFAGPVDLCTYPKYCTVIAYPTDLNTIRTRLANRFYRRISALVWEVRYIESNARTFNEPGSAIARAAKKITTQLLKFINDQDCTNIFDLCSTTDDEQDCLDADDLDDEKCRPRTSYRRRKGRGKRGKSMKNGYDENCWKKQCMELVNLIFQCEDSEPFRQPVDLDQYPDYRHIIDTPMDFGTVKETLEAGNYDTPMELCKDIRLIFSNAKSYTPNKKSKIYSMTLRLSALFEEKIRRIVSDFKNGQKQNEKIRRNQRYTRRVQSQSSAQHPTKMPSRNLKQKPLKSQAKIESEQEDSFSQPTSSRAACVASHKTNASNYNHSSSGESSDSACLASFERNGKARSTTLTNRSTLSSAESEVEGSLASSTPSSSSTEESSEESKESSVALVSPPLHNGICRRKNINCRITRNQAAQRKQIGTLPQENGNTRKAVRKRLYESDSENTSAVTSESLSNSTGRHRKIPRRSATVAATKLRLMSDVEEEVSSSESIGIGCKNRKLPHRNASAAARRMLLEGSEDDAGLKSESEKETEEQLTKRKVLSLSTSSAVRRKFVSESENESSDSETDTQMKQKTWQSNGHRQLRGTALSASPEMRSPTRGFSEEDSKSHNSEDGSSQKAEQSMSANKFVVSNSEDEACSESDRWNARKLFGLHLVAPIKKAKVLSDLEDTAESETEDRQDGRSVVSETLVPCRITASPNSGPGADFNDSCDTESETNSNNSNYFDASSKTKKRKRKGKTKIFRKESTSEEPGQSGKVLRSRTCIINYRKHIKVSNVTEKKNPRRCATLAANKIKIMSDTKEELSSSESVCTVKKNRRQLHGSASGASKKKPISSSDIDVSVMSENEKEQDSDGKNDFCSGSSAPKRKYISESEDEKTESEVEIEVTKKENDNDSQTKRTESDAALKNTFDSSEENSTNHKVENGRNWRTSGQSTSAYNHHVSNSEEEVSSELAKRETKTIRRARNKRSRAPLKRLKLSNDLKETSESAAGRKIEEKSSVSENVETPGTAGSSKANLNCSSDSDSGTDNSIYSDATETKKRKTDIVRKEISNLPKTSRRPQRRKRRKPKQENDSEDLEYTKYRRANRRTKIRTRNRGRRTVRYDDCDDDDDDRGVGDAACET", "length": 2306, "header": "tr|A0A8V0YI94-1|A0A8V0YI94_CHICK Isoform 1 of Bromodomain and WD repeat-containing protein 1 OS=Gallus gallus OX=9031 GN=BRWD1 PE=4 SV=1 CANONICAL=A0A8V0YI94-1" }, "locus": { "chromosome": "1", "start_pos": 108075542, "end_pos": 108024864, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010035424.1", "url": "https://www.ensembl.org/id/ENSGALT00010035424.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020618.1", "url": "https://www.ensembl.org/id/ENSGALP00010020618.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-1266695", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1266695", "resource": "Reactome", "description": "Interleukin-7 signaling" }, { "id": "R-GGA-3247509", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3247509", "resource": "Reactome", "description": "Chromatin modifying enzymes" } ], "orthologs": [ { "uniprot_canonical_ac": "A0ABK0LKM2-1", "protein_name": "Bromodomain and WD repeat-containing protein 1", "gene_name": "Brwd1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAEPSPARRPVPLIESELYFLIARYLSAGPCRRAAQVLVQELEQYQLLPKRLDWEGNEHNRSYEELVLSNKHVAPDHLLQICQRIGPMLDKEAPPSISRVTSLLGAGRQSLLRTAKDCRHTVWKGSAFAALHRGRPPEMPVNYGPPPSLVDIHRGKQLTGCSTFSTAFPGTMYQHIKMHRRILGHLSAVYCVAFDRTGHRIFTGSDDCLVKIWSTHNGRLLSTLRGHSAEISDMAVNYENTLIAAGSCDKIIRVWCLRTCAPVAVLQGHTGSITSLQFSPMAKGPQRYMVSTGADGTVCFWQWDLESLKFSPRPLKFTEKPRPGVQMLCSSFSVGGMFLATGSTDHVIRMYFLGFEAPEKIAELESHTDKVDSIQFCNNGDRFLSGSRDGTARIWRFEQLEWKSILLDMAARISGDTSAEEERFMKPKVTMIAWNQDDSTVVTAVNDHVLKVWSSYTGQLLHNLLGHADEVFVLETHPFDSRIMLSAGHDGSIFIWDITKGIKMKHYFNMIEGQGHGAVFDCKFSQDGQHFACTDSHGHLLIFGFGCSKPYEKIPDQMFFHTDYRPLIRDSNNYVLDEQTQQAPHLMPPPFLVDVDGNPHPTKFQRLVPGRENSADEHLVPQLGYVATSDGEVIEQVISLHTNDSGDASPESSVLDGMIRQLQQQQDLRLGVDQDVTANGLPNEEGTPRRGSFRRLSLDIQSPPNIGLRRSGQVEGVRQMHQNAPRSQIATERDLQAWKRRVVVPEAPPGVFRRLEDIRIERGEEERNLYVIGRKKKTFQLPQKSNSMVLVSQSRQRTCRRKYANYSRRNAGQCELSSGNESSGSVRHETSCDQSEGSCSSEDDEWRSDRRSGSDSDSPSESSSQYSDWTADTGVHLEPPLRTSCRRRVTRFCSTSEDEMSTENISPPKRRRKRRKESKPKRESLRRTTPAELANMEPLYEFHPPVWITDTTLRKSPFVPQMGDEVMYFRQGHEAYIEAVRRNNIYELNPNKEPWRKMDLRDQELVKIVGLRYEVGPPTLCCLKLAFIDPATGRLTDKSFSIRYHDMPDVIDFLVLRQFYDEARQRNWQPSDRFRSIIDDAWWFGTVLSQEPYQPQYPDSHFQCYSVRWDNTEIEKLSPWDMEPIPDNVDPPEELGASISVTSDELEKLLYKPQDGEWGQRSRDEECERIISGIDQLLNLDIAAAFAGPVDLCTYPKYCTVVAYPTDLYTIRMRLVHRFYRRLSALIWEVRYIEHNARTFNEPESVIARSAKKITDQLLKFIKNQDCTNILELCNTSDSDGDSADDLDDSDLPKTSSGRRRVHNWKRRSRGSSCIESDWRRQCKALLILIFQCEDSEPFRQPVDLVEYPDYRDIIDTPMDFGTVRETLEAGNYDSPVEFCKDIRLIFSNAKAYTPNKRSKIYSMTLRLSALFEEKMKKISFDFKIGQKFKEKLRRSQRFKQRQKCNGAVPVDRSMRSVKQKQFRSQTKVIPQLMCSPSQSTSSKVPLSATRKTSAGVSSGCTSGDSSDSAGSLERVRRHRAETLRSGSVLFGSEMEDFLATSSSSSSSNSSDESKESSGAQECSLRSGVLRSSNLRVTRTRAARRKAGSVSLENGCGRKATRKRVYLSDSDNHSVETDENLKSKAGSSRKVLRKCAAVAASKIKLMSDAEDSSSESPCSGRKLPHRNASAVARKKLLHNSDDQSLKSETEEVRDRNQALLMSSPHAVQNCISDSESDSDLQAARKTWHANGCTSHPAAACKAKSRPIESSEEDSRCHESDHGPSSTVDPLTSGQKLGADSISEEADSEPGSSALGKNTHLSKKAKILSDSEDCEEKYGERRGPEVEGSPVSEALREAVIVPQCLSHHGPETDVDSDGSAVREKSHSNVNDSVSRENGQRKKVSRKRFCSSDSESNLQVIQKSPIDQTSPSRITRSAGMVTDKTKLTSDAEDVSLESVCTRSKRRRKKPVRFACTTAKSIPSSEGKHARCEVPEEQSACRSSLAEPEQQGSAENASQAANADLDFEGSSSFEQTKSIQKRQMDSVCIRAPSKTQNSSAGPSQEDPKSHTQDSDISLSSESVLAQKAIGENNFEEELNYGLRRWNGRRLRTYGKAPLSRTAPVTPSLQAAAEVRVKRRRVHPEVDGEDIPGQMGSSGCGPDTSPKSSDLGSVTESDVDCTDNTKAQRRKKRKGKTRVLSQESVRKDREPHTKTRPCMFNEKEAVQMHSDTLKPKTVPEKIPRRCAAIAANKIKTMCNLKEVVSGPENVGIRTNSRKLPYRQASAAAKKKLLSVYKEDDALIHSENEEEVYLRRFRSQKEKAQQSP", "length": 2303 }, "evidence": [ { "id": "A0A8V0YI94", "url": "https://omabrowser.org/oma/group/A0A8V0YI94/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1MTQ0-1", "protein_name": "Bromodomain and WD repeat-containing protein 1", "gene_name": "BRWD1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAEPSPARRPVPLIESELYFLIARYLSAGPCRRAAQVLVQELEQYQLLPKRLDWEGNEHNRSYEELVLSNKHVAPDHLLQICQRIGPMLDKEIPPSISRVTSLLGAGRQSLLRTAKDCRHTVWKGSAFAALHRGRPPEMPVNYGSPPNLVEIHRGKQLTGCSTFSTAFPGAMYQHIKMHRRILGHLSAVYCVAFDRTGHRIFTGSDDCLVKIWSTHNGRLLSTLRGHSAEISDMAVNYENTMIAAGSCDKIIRVWCLRTCAPVAVLQGHTGSITSLQFSPMAKGSQRYMVSTGADGTVCFWQWDLESLKFSPRPLKFTEKPRPGVQMLCSSFSVGGMFLATGSTDHVIRMYFLGFEAPEKIAELESHTDKVDSIQFCNNGDRFLSGSRDGTARIWRFEQLEWRSILLDMATRISGDLSLEEERFMKPKVTMIAWNQNDSIVVTAVNDHVLKVWNSYTGQLLHNLLGHADEVFVLETHPFDSRIMLSAGHDGSIFIWDITKGTKMKHYFNMIEGQGHGAVFDCKFSQDGQHFACTDSHGHLLIFGFGCSKPYEKIPDQMFFHTDYRPLIRDSNNYVLDEQTQQAPHLMPPPFLVDVDGNPHPTKYQRLVPGRENSADEHLVPQLGYVATSDGEVIEQIISLQTNDNGERSPERSVLDGMIRQLQQQQDQRMGAGQEAVPSGLSNGEETPRRGFRRLSLDIQSPPNIGLRRSGQVEGVRQMHQNAPRSQMATERDLQAWKRRVVVPEVPLGIFRKLEDFRIEKGEQERNLYIIGRKRKTLQFSQKSDSVTFMSQSRQRTCRRKYPNYGRRNLGRLELSSGNESSSSIRHETSCDQSEGSCSSEEEEWKSDRRSESDSESSSDSSSRYSDWTADAGIHLQPPLRTSSRRRITRFCSSSEDEMSAENLSPPKRRRKRKKENKPKKENLRRMTQAELADVEHLYEFHPPVWITDTTLRKSPFVPQMGDEVIYFRQGHEAYIEAVRRNNIYELNPNKEPWRKMDLRDQELVKIVGIRYEVGPPTLCCLKLAFIDPATGKLMDKSFSIRYHDMPDVIDFLVLRQFYDEARQRNWQSCDRFRSIIDDAWWFGTVLRQEPYQPQYPDSHFQCYIVRWDNTEIEKLSPWDMEPIPDNVDPPEELGASISVTSDELEKLLYKPQDGEWGQKSRDEECERIISGIDQLLNLDIAAAFAGPVDLCTYPKYCTVVAYPTDLYTIRMRLVNRFYRRLSALVWEVRYIEHNARTFNEPESVIARSAKKITDQLLKFIKNQDCINISELSNTSENDEQNAEDLDDSDLPKTSSGRRRVHDWKKRSIKTTNYVENNWKKQCKELVNLIFQCEDSEPFRQPVDLVEYPDYRDIIDTPMDFGTVRETLEAGNYDSPLEFCKDIRLIFSNAKAYTPNKRSKIYSMTLRLSALFEEKMKKISSDFKIGQKFSEKLRRSQRFKRRQNCNRVNQANKSIRNTKQKRLKSQTKVISEFVGSPIQPTSSRATYSASHKTTASVSSGVTSGDSSDSAASSERMRRNRPVTLTNGSTLSESEMEDSLGTSSSSSASNSSEESKESPRARDSSSRSGLARSSNLRVTRTRAAQRKTGPVSLENGCGRKATRKRVYLSDSDNNSLATGESVKVRAGNNRKVLRKCAAVAANKIKLMSDVEENSTSESVCSGRKLPHRNASAVARKKLLHNSEDDQSLKSELEEEELKDQLSPLSNSLAAQNTENGDSESESDLRVARKNWHANGYKSQIPATSKTKFLKIASSEEDSKSHDSDNGHSRTAGPSTSLLKLKAESISEEEEKANSETRKYSSRKYSTGRKNAPFLKKAKLFSDSEDSESDKEDGQDRCHKMEMNPSSGNVECEPAARSQCFSDHVSETDLDSDDDKKAKEKPNSFIKDSASQNHGQSRKAARKRVCSSDSDSNSKVVKKASRARPGLLRVPRRCATTAASRIKLMSDEEDGRVDHVCTRRKNARKKPLHIACAPAQKIDSNSEGDVNCEVPNEQSGCEGQPLDADSEGSAKSISQSLNEDSDSEGVLNSGHKNRHTRSLKTSVASSKTKNALIVSLEEDSKSHIPRGEIGRKCSSESTLVHKATAENNFEEELNYGLRRWNGRRLRTYGKAPFSKTKVVRDSQEAAETEVKRKRLQTELENVKASETTGSSKCGPDTSPKSDSDLGSATESDADCTDDSKTKKRKTKGKAKVVRKESVPRDREPNTKMRTCVHNQKDAVPMPSETLKAKMVPEKVPRRCATVAANKIKIMSNLKETISGPENVWIRKSSRKLPHRNASAAAKKKLLNVYKEDDTTINSESEKELEDINRKMPLLRRFRSWKEKAQ", "length": 2323 }, "evidence": [ { "id": "A0A8V0YI94", "url": "https://omabrowser.org/oma/group/A0A8V0YI94/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q921C3-1", "protein_name": "Bromodomain and WD repeat-containing protein 1", "gene_name": "Brwd1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAEPSPARRPVPLIESELYFLIARYLSAGPCRRAAQVLVQELEQYQLLPKRLDWEGNEHNRSYEELVLSNKHVAPDHLLQICQRIGPMLDKEVPPSISRVTSLLGAGRQSLLRTAKDCRHTVWKGSAFAALHRGRPPEMPVNYGPPPSLVEIHRGRQLTGCSTFSTAFPGTMYQHIKMHRRILGHLSAVYCVAFDRTGHRIFTGSDDCLVKIWSTHNGRLLSTLRGHSAEISDMAVNYENTLIAAGSCDKIIRVWCLRTCAPVAVLQGHTGSITSLQFSPMAKGPQRYMVSTGADGTVCFWQWDLESLKFSPRPLKFTEKPRPGVQMLCSSFSVGGMFLATGSTDHVIRMYFLGFDAPEKIAELESHTDKVDSIQFCNNGDRFLSGSRDGTARIWRFEQLEWRSILLDMSARISGDTSSEEERFMKPKVTMIAWNQDDSTVVTAVNDHVLKVWSSYTGQLLHNLLGHADEVFVLETHPFDSRIMLSAGHDGSIFIWDITKGIKMKHYFNMIEGQGHGAVFDCKFSQDGQHFACTDSHGHLLIFGFGCSKPYEKIPDQMFFHTDYRPLIRDSNNYVLDEQTQQAPHLMPPPFLVDVDGNPHPTKFQRLVPGRENSADEHLVPQLGYVATSDGEVIEQIISLHTNDSGDASPESSVLDGMIRQLQQQQDQRLGVDQDGTANGLPSGEGTPRRGSFRRLSLDIQSPPNIGLRRSGQVEGVRQMHQNAPRSQIATERDLQAWKRRVVVPEAPPGMFRRLEDIRIERGEEERNLYVIGRKKKTFQVPQKSNSMVLVSQSRQRTCRRKYANYSRRNADQCELSSGNESSGSVRHETSYDQSEGSCSSEDDEWRNDRRSGSDSDSSSDSSSQYSDWTADTGINLQPPLRMSCRRRVTRFCSTSEDEMSMENISPPKRRRKRRKESKPKRESLRRMTPAELANMEHLYEFHPPVWITDTTLRKSPFVPQMGDEVMYFRQGHEAYIEAVRRNNIYELNPHKEPWRKMDLRDQELVKIVGLRYEVGPPTLCCLKLAFIDPATGRLTDKSFSIRYHDMPDVIDFLVLRQFYDEARQRNWQPCDRFRSIIDDAWWFGTVLSQEPYQPQYPDSHFQCYIVRWDNTETEKLSPWDMEPIPDNVDPPEELGASISVTSDELEKLLYKPQEGEWGQRSRDEECDRIISGIDQLLNLDIAAAFAGPVDLCTYPKYCTVVAYPTDLYTIRMRLVNRFYRRLSALIWEVRYIEHNARTFNEPESVIARSAKKITDQLLKFIKNQDCTNISELCNTSDNDEDDSADDLDDSDLPKTSSGRRKVHNWKRRSRASGCIESDWRRQCKALLILIFQCEDSEPFRQPVDLDEYPDYRDIIDTPMDFGTVRETLEAGNYDSPVEFCKDIRLIFSNAKAYTPNKRSKIYSMTLRLSALFEEKMKKISFDFKIGQKFKEKLRRSQRFKQRQNCNGAVPGDRRRRNVKQKQFKSQTKVIPQLMCPPSQSTSSKVPLSATRKTSAGVSSGFTSGDSSDSAGSLERVRRQRPEVLRSGSVLFGSEMEDFLATSSSSSASNSSEESKASPGARESSLRSGVLRGSNLGVTRTRAARRKAGSVSLENGCGRKATRKRVYLSDSDNNSVETDENLKNRKCGSSRKVLRKCAAVAASKIKLMSDAEDSSSESPCSGRKLPHRNASAVARKKLLHNSDDQSLKSETEELKDQNQSLLISGPHSVHNSISDSESDSDLRATRKTWNANGCTSHTAATCKTKSRPIESSEEDSRCHGSDHGPSSTGDPSTSGQKLRADSISEEADSEPESSVLCKNTHLCKKAKILSDSEDCEEKCGERRGPEVEGSPVSEALREAILAPQCLSHRGSETDVDSDGGAVREKSYSNENGSVSLENGQRRKVSRKSSSDKESNLQVTQKSPKDRSSPSRITQRASVATDKMKLTSDAEDLSLESVCTRSKRRRKKPARFACTPAKTALSSEEKHAHCEVPEAQPACRNKLPEPEHQDSAENPSQAASADLNSGGGSSFEQRKSIQSRQMGAVCVRPPPKTQSSSAGLSQENARSQTLDSETSLPSESVLTQKATVESNFEEELNYGLRRWNGRRLRTYGKAPLSRTAQVTPSLQASAEVGVKRRRMHPEVDGEDVPGQMGSSGCGPDTSPKASDLGSVTDSDVDCTDNTQTQRKKKRKGKARVLSKESVRKDREPHTKMRPCMLNEKDAVQMHSDTLKAKTVPEKVPRRCATVAANKIKMMCNLKEVVSGPENVGIRTISRKLPYRQASAAAKKKLLSVYKEDDAPIHSENEKELYLRRFRSRKEKAQPTPR", "length": 2304 }, "evidence": [ { "id": "A0A8V0YI94", "url": "https://omabrowser.org/oma/group/A0A8V0YI94/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9NSI6-1", "protein_name": "Bromodomain and WD repeat-containing protein 1", "gene_name": "BRWD1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAEPSSARRPVPLIESELYFLIARYLSAGPCRRAAQVLVQELEQYQLLPKRLDWEGNEHNRSYEELVLSNKHVAPDHLLQICQRIGPMLDKEIPPSISRVTSLLGAGRQSLLRTAKDCRHTVWKGSAFAALHRGRPPEMPVNYGSPPNLVEIHRGKQLTGCSTFSTAFPGTMYQHIKMHRRILGHLSAVYCVAFDRTGHRIFTGSDDCLVKIWSTHNGRLLSTLRGHSAEISDMAVNYENTMIAAGSCDKIIRVWCLRTCAPVAVLQGHTGSITSLQFSPMAKGSQRYMVSTGADGTVCFWQWDLESLKFSPRPLKFTEKPRPGVQMLCSSFSVGGMFLATGSTDHVIRMYFLGFEAPEKIAELESHTDKVDSIQFCNNGDRFLSGSRDGTARIWRFEQLEWRSILLDMATRISGDLSSEEERFMKPKVTMIAWNQNDSIVVTAVNDHVLKVWNSYTGQLLHNLMGHADEVFVLETHPFDSRIMLSAGHDGSIFIWDITKGTKMKHYFNMIEGQGHGAVFDCKFSQDGQHFACTDSHGHLLIFGFGCSKPYEKIPDQMFFHTDYRPLIRDSNNYVLDEQTQQAPHLMPPPFLVDVDGNPHPTKYQRLVPGRENSADEHLIPQLGYVATSDGEVIEQIISLQTNDNDERSPESSILDGMIRQLQQQQDQRMGADQDTIPRGLSNGEETPRRGFRRLSLDIQSPPNIGLRRSGQVEGVRQMHQNAPRSQIATERDLQAWKRRVVVPEVPLGIFRKLEDFRLEKGEEERNLYIIGRKRKTLQLSHKSDSVVLVSQSRQRTCRRKYPNYGRRNRSWRELSSGNESSSSVRHETSCDQSEGSGSSEEDEWRSDRKSESYSESSSDSSSRYSDWTADAGINLQPPLRTSCRRRITRFCSSSEDEISTENLSPPKRRRKRKKENKPKKENLRRMTPAELANMEHLYEFHPPVWITDTTLRKSPFVPQMGDEVIYFRQGHEAYIEAVRRNNIYELNPNKEPWRKMDLRDQELVKIVGIRYEVGPPTLCCLKLAFIDPATGKLMDKSFSIRYHDMPDVIDFLVLRQFYDEARQRNWQSCDRFRSIIDDAWWFGTVLSQEPYQPQYPDSHFQCYIVRWDNTEIEKLSPWDMEPIPDNVDPPEELGASISVTTDELEKLLYKPQAGEWGQKSRDEECDRIISGIDQLLNLDIAAAFAGPVDLCTYPKYCTVVAYPTDLYTIRMRLVNRFYRRLSALVWEVRYIEHNARTFNEPESVIARSAKKITDQLLKFIKNQHCTNISELSNTSENDEQNAEDLDDSDLPKTSSGRRRVHDGKKSIRATNYVESNWKKQCKELVNLIFQCEDSEPFRQPVDLVEYPDYRDIIDTPMDFGTVRETLDAGNYDSPLEFCKDIRLIFSNAKAYTPNKRSKIYSMTLRLSALFEEKMKKISSDFKIGQKFNEKLRRSQRFKQRQNCKGDSQPNKSIRNLKPKRLKSQTKIIPELVGSPTQSTSSRTAYLGTHKTSAGISSGVTSGDSSDSAESSERRKRNRPITNGSTLSESEVEDSLATSLSSSASSSSEESKESSRARESSSRSGLSRSSNLRVTRTRAAQRKTGPVSLANGCGRKATRKRVYLSDSDNNSLETGEILKARAGNNRKVLRKCAAVAANKIKLMSDVEENSSSESVCSGRKLPHRNASAVARKKLLHNSEDEQSLKSEIEEEELKDENQLLPVSSSHTAQSNVDESENRDSESESDLRVARKNWHANGYKSHTPAPSKTKFLKIESSEEDSKSHDSDHACNRTAGPSTSVQKLKAESISEEADSEPGRSGGRKYNTFHKNASFFKKTKILSDSEDSESEEQDREDGKCHKMEMNPISGNLNCDPIAMSQCSSDHGCETDLDSDDDKIEKPNNFMKDSASQDNGLSRKISRKRVCSSDSDSSLQVVKKSSKARTGLLRITRRCAATAANKIKLMSDVEDVSLENVHTRSKNGRKKPLHLACTTAKKKLSDCEGSVHCEVPSEQYACEGKPPDPDSEGSTKVLSQALNGDSDSEDMLNSEHKHRHTNIHKIDAPSKRKSSSVTSSGEDSKSHIPGSETDRTFSSESTLAQKATAENNFEVELNYGLRRWNGRRLRTYGKAPFSKTKVIHDSQETAEKEVKRKRSHPELENVKISETTGNSKFRPDTSSKSSDLGSVTESDIDCTDNTKTKRRKTKGKAKVVRKEFVPRDREPNTKVRTCMHNQKDAVQMPSETLKAKMVPEKVPRRCATVAANKIKIMSNLKETISGPENVWIRKSSRKLPHRNASAAAKKKLLNVYKEDDTTINSESEKELEDINRKMLFLRGFRSWKENAQ", "length": 2320 }, "evidence": [ { "id": "A0A8V0YI94", "url": "https://omabrowser.org/oma/group/A0A8V0YI94/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YI94", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI94" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YI94", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI94" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YI94", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI94" } ], "pmid": "" }, { "name": "motile cilium", "id": "GO:0031514", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031514", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YI94", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI94" } ], "pmid": "" }, { "name": "axoneme", "id": "GO:0005930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005930", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YI94", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI94" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YI94", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI94" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YI94", "url": 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"https://www.uniprot.org/uniprotkb/A0A8V0YIA4/entry#A0A8V0YIA4-1", "sequence": { "sequence": "MVTIAIHGGGGSILDNGAYNAKIGYSHAHVSVIPNCQFRSKTARLKTFTANQLDEIKDPSGLFYILPFQKGYLVNWDVQRQVWDYLFGKEMYQVDFVDTNIIITEPYFNFSSIQESMNEILFEEYQFQAVLRVNAGALSAHRYFRDNPSELCCIIVDSGYSFTHIVPYCRSKKKKEAIIRINVGGKLLTNHLKEIISYRQLHVMDETHVINQVKEDVCYVSQDFYKDMEIAKLKGEENTVMVDYVLPDFSTIKKGFCKPREEMVLSGKYKTGEQILRLTNERFAVPEILFHPSDIGIQEMGIPEAIVDSIQNLPEEMQPHFFKNIVLTGGNTLFPGFRDRVYSEVRCLTPTDYDVSVVLPENPITYSWEGGKLISENDDFEDLVVTREDYEEHGHNICEEKFDI", "length": 404, "header": "tr|A0A8V0YIA4-1|A0A8V0YIA4_CHICK Isoform 1 of Actin-related protein 6 OS=Gallus gallus OX=9031 GN=ACTR6 PE=3 SV=1 CANONICAL=A0A8V0YIA4-1" }, "locus": { "chromosome": "1", "start_pos": 47297214, "end_pos": 47288446, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027530.1", "url": "https://www.ensembl.org/id/ENSGALT00010027530.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015767.1", "url": "https://www.ensembl.org/id/ENSGALP00010015767.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "nucleolus organization", "id": "GO:0007000", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007000", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIA4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIA4" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIA4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIA4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIA4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIA4" } ], "pmid": "" }, { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIA4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIA4" } ], "pmid": "" }, { "name": "Swr1 complex", "id": "GO:0000812", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000812", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIA4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIA4" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIA4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIA4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "nucleosome binding", "id": "GO:0031491", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031491", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIA4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIA4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 109, "end_pos": 111, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 109, "end_pos": 111 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", 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}, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YIA7-1", "uniprot_ac": "A0A8V0YIA7", "uniprot_id": "A0A8V0YIA7_CHICK", "mass": { "chemical_mass": 107278.0, "monoisotopic_mass": 107278.0 }, "refseq": { "ac": "XP_040512449", "name": "ankycorbin isoform X9", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040512449" }, "gene_names": [ { "name": "RAI14", "type": "recommended", "evidence": [ { "id": "A0A8V0YIA7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIA7" } ] }, { "name": "RAI14", "type": "synonym", "evidence": [ { "id": "XP_040512449", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040512449" } ] } ], "protein_names": [ { "name": "Retinoic acid induced 14", "type": "synonym", "evidence": [ { "id": "A0A8V0YIA7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIA7/entry#names_and_taxonomy" } ] }, { "name": "ankycorbin isoform X9", "type": "synonym", "evidence": [ { "id": "XP_040512449", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040512449" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052572.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040512449", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040512449" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIA7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIA7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RAI14", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIA7", "locus": { "chromosome": "Z", "start_pos": 11102443, "end_pos": 11009400, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013214", "url": "https://www.ensembl.org/id/ENSGALG00010013214" } ] } } ], "crossref": [ { "id": "A0A8V0YIA7", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YIA7", "database": 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"tr|A0A8V0YIA7-1|A0A8V0YIA7_CHICK Isoform 1 of Retinoic acid induced 14 OS=Gallus gallus OX=9031 GN=RAI14 PE=1 SV=1 CANONICAL=A0A8V0YIA7-1" }, "locus": { "chromosome": "Z", "start_pos": 11100514, "end_pos": 11020497, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031728.1", "url": "https://www.ensembl.org/id/ENSGALT00010031728.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018575.1", "url": "https://www.ensembl.org/id/ENSGALP00010018575.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "actin binding", "id": "GO:0003779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003779", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIA7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIA7" } ], "pmid": "" } ] }, { "name": "Cellular Component", 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"MMAIRVEMRTFFILAALLGLFVTIKAQEEEDYDAGEDVEEIACTQNGQMYLNRDIWKPSPCQICVCDNGAILCDEIQCQDVLECENPQVPPGECCPVCPHTARDFDPTVGRGRKGQKGEPGIVPPVSGIRGRPGPAGPPGSQGPRGERGPKGRPGPRGPQGIDGEPGIPGQPGDPGPPGHPTHTGPDGLSRPFAAQMAGLDEKSGLGSQMGLMPGAVGPVGPRGPQGLQGKQGGAGPTGPPGEPGDPGPMGPVGSRGPEGPPGKPGEDPVLQ", "length": 272, "header": "tr|A0A8V0YIB0-1|A0A8V0YIB0_CHICK Isoform 1 of VWFC domain-containing protein OS=Gallus gallus OX=9031 GN= PE=1 SV=1 CANONICAL=A0A8V0YIB0-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YIB0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIB0/entry#A0A8V0YIB0-1", "sequence": { "sequence": "MMAIRVEMRTFFILAALLGLFVTIKAQEEEDYDAGEDVEEIACTQNGQMYLNRDIWKPSPCQICVCDNGAILCDEIQCQDVLECENPQVPPGECCPVCPHTARDFDPTVGRGRKGQKGEPGIVPPVSGIRGRPGPAGPPGSQGPRGERGPKGRPGPRGPQGIDGEPGIPGQPGDPGPPGHPTHTGPDGLSRPFAAQMAGLDEKSGLGSQMGLMPGAVGPVGPRGPQGLQGKQGGAGPTGPPGEPGDPGPMGPVGSRGPEGPPGKPGEDPVLQ", "length": 272, "header": "tr|A0A8V0YIB0-1|A0A8V0YIB0_CHICK Isoform 1 of VWFC domain-containing protein OS=Gallus gallus OX=9031 GN= PE=1 SV=1 CANONICAL=A0A8V0YIB0-1" }, "locus": { "chromosome": "7", "start_pos": 622976, "end_pos": 558308, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031341.1", "url": "https://www.ensembl.org/id/ENSGALT00010031341.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018277.1", "url": "https://www.ensembl.org/id/ENSGALP00010018277.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 238, "start_aa": "Thr", "end_pos": 238, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr238", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ 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}, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YIB9-1", "uniprot_ac": "A0A8V0YIB9", "uniprot_id": "A0A8V0YIB9_CHICK", "mass": { "chemical_mass": 60213.0, "monoisotopic_mass": 60213.0 }, "refseq": { "ac": "XP_040506971", "name": "protein APCDD1-like isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040506971" }, "gene_names": [ { "name": "APCDD1L", "type": "recommended", "evidence": [ { "id": "A0A8V0YIB9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIB9" } ] }, { "name": "APCDD1L", "type": "synonym", "evidence": [ { "id": "XP_040506971", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040506971" } ] } ], "protein_names": [ { "name": "APC down-regulated 1 like", "type": "synonym", "evidence": [ { "id": "A0A8V0YIB9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIB9/entry#names_and_taxonomy" } ] }, { "name": "protein APCDD1-like isoform X2", "type": "synonym", "evidence": [ { "id": "XP_040506971", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040506971" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 1% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052551.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040506971", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040506971" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIB9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIB9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "APCDD1L", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIB9", "locus": { "chromosome": "20", "start_pos": 11516635, "end_pos": 11500807, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010014777", "url": "https://www.ensembl.org/id/ENSGALG00010014777" } ] } } ], "crossref": [ { "id": "A0A8V0YIB9", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YIB9", "database": "AlphaFoldDB", "categories": [] }, { "id": "419316", "url": "https://www.ncbi.nlm.nih.gov/gene/419316", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR029405", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029405", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042425", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042425", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:419316", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419316", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "RTWEGYY", "url": "https://omabrowser.org/oma/group/RTWEGYY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YIB9", "url": "https://www.orthodb.org/?gene=A0A8V0YIB9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YRH5", "url": "https://www.orthodb.org/?gene=A0A8V0YRH5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YWH7", "url": "https://www.orthodb.org/?gene=A0A8V0YWH7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31021", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31021", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31021:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31021:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF14921", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14921", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_040506971", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040506971", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YIB9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIB9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YIB9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIB9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YRH5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRH5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YRH5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRH5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YWH7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YWH7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YWH7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YWH7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAGTGAGSRQQRGLCAGPRVCVCVCVCIRVCARAQPRGADRLRTFSPPPRAVYAAAERSLRWEPRCRQQLRHLQDGARIAARLPPRLEGQWVSTGCEVRPGPEFLTRSYLFYANRLFKAFQFYYWDPSCREPSYSLVIKGKLRLRQASWITRGATEADYHLHKVGIVFHSQKAMREVASRINQSSGEGCSGFLPPGRAWAPRALYELLSAKTERDCTAALGFAMHELSLVRVERHHQPLPGLQQSGSSLVEELYLGDIHTDWLERLHYRPTGYQRPLQSVVHHMHPCPACGVIYRADEHHPPILPARAELPVQLSGSWVSTRCEVRPAVLFLTRYFIFHGSNHTWQGYYYHYSDPLCKQPTFTIYASGRYTQGIPSSKVRGGMELAFKVTQARVTPMDQVTVMMLNSSEPGSCGLASSWSAGVEQDITPTNGCLALGIRLPHTEYELFRTEHDPKERSLLYIGERPTDGSSPDRPDKRPTSYQAPLVQCAAASEEFPNYYSLKYVGKEGANGSEELKPLPVALLLLIALQLLRWD", "length": 536, "header": "tr|A0A8V0YIB9-1|A0A8V0YIB9_CHICK Isoform 1 of APC down-regulated 1 like OS=Gallus gallus OX=9031 GN=APCDD1L PE=4 SV=1 CANONICAL=A0A8V0YIB9-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YIB9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIB9/entry#A0A8V0YIB9-1", "sequence": { "sequence": "MAAGTGAGSRQQRGLCAGPRVCVCVCVCIRVCARAQPRGADRLRTFSPPPRAVYAAAERSLRWEPRCRQQLRHLQDGARIAARLPPRLEGQWVSTGCEVRPGPEFLTRSYLFYANRLFKAFQFYYWDPSCREPSYSLVIKGKLRLRQASWITRGATEADYHLHKVGIVFHSQKAMREVASRINQSSGEGCSGFLPPGRAWAPRALYELLSAKTERDCTAALGFAMHELSLVRVERHHQPLPGLQQSGSSLVEELYLGDIHTDWLERLHYRPTGYQRPLQSVVHHMHPCPACGVIYRADEHHPPILPARAELPVQLSGSWVSTRCEVRPAVLFLTRYFIFHGSNHTWQGYYYHYSDPLCKQPTFTIYASGRYTQGIPSSKVRGGMELAFKVTQARVTPMDQVTVMMLNSSEPGSCGLASSWSAGVEQDITPTNGCLALGIRLPHTEYELFRTEHDPKERSLLYIGERPTDGSSPDRPDKRPTSYQAPLVQCAAASEEFPNYYSLKYVGKEGANGSEELKPLPVALLLLIALQLLRWD", "length": 536, "header": "tr|A0A8V0YIB9-1|A0A8V0YIB9_CHICK Isoform 1 of APC down-regulated 1 like OS=Gallus gallus OX=9031 GN=APCDD1L PE=4 SV=1 CANONICAL=A0A8V0YIB9-1" }, "locus": { "chromosome": "20", "start_pos": 11515355, "end_pos": 11511572, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010035529.1", "url": "https://www.ensembl.org/id/ENSGALT00010035529.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020644.1", "url": "https://www.ensembl.org/id/ENSGALP00010020644.1" } ] } }, { "isoform_ac": "A0A8V0YRH5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIB9/entry#A0A8V0YRH5-1", "sequence": { "sequence": "MVRCWWLAGLLVVYAAAERSLRWEPRCRQQLRHLQDGARIAARLPPRLEGQWVSTGCEVRPGPEFLTRSYLFYANRLFKAFQFYYWDPSCREPSYSLVIKGKLRLRQASWITRGATEADYHLHKVGIVFHSQKAMREVASRINQSSGEGCSGFLPPGRAWAPRALYELLSAKTERDCTAALGFAMHELSLVRVERHHQPLPGLQQSGSSLVEELYLGDIHTDWLERLHYRPTGYQRPLQSVVHHMHPCPACGVIYRADEHHPPILPARAELPVQLSGSWVSTRCEVRPAVLFLTRYFIFHGSNHTWQGYYYHYSDPLCKQPTFTIYASGRYTQGIPSSKVRGGMELAFKVTQARVTPMDQVTVMMLNSSEPGSCGLASSWSAGVEQDITPTNGCLALGIRLPHTEYELFRTEHDPKERSLLYIGERPTDGSSPDRPDKRPTSYQAPLVQCAAASEEFPNYYSLKYVGKEGANGSEELKPLPVALLLLIALQLLRWD", "length": 496, "header": "tr|A0A8V0YRH5-1|A0A8V0YRH5_CHICK Computationally mapped isoform of APC down-regulated 1 like OS=Gallus gallus OX=9031 GN=APCDD1L PE=4 SV=1 CANONICAL=A0A8V0YIB9-1" }, "locus": { "chromosome": "20", "start_pos": 11515355, "end_pos": 11501543, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010035535.1", "url": "https://www.ensembl.org/id/ENSGALT00010035535.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020648.1", "url": "https://www.ensembl.org/id/ENSGALP00010020648.1" } ] } }, { "isoform_ac": "A0A8V0YWH7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIB9/entry#A0A8V0YWH7-1", "sequence": { "sequence": "MAAVYAAAERSLRWEPRCRQQLRHLQDGARIAARLPPRLEGQWVSTGCEVRPGPEFLTRSYLFYANRLFKAFQFYYWDPSCREPSYSLVIKGKLRLRQASWITRGATEADYHLHKVGIVFHSQKAMREVASRINQSSGEGCSGFLPPGRAWAPRALYELLSAKTERDCTAALGFAMHELSLVRVERHHQPLPGLQQSGSSLVEELYLGDIHTDWLERLHYRPTGYQRPLQSVVHHMHPCPACGVIYRADEHHPPILPARAELPVQLSGSWVSTRCEVRPAVLFLTRYFIFHGSNHTWQGYYYHYSDPLCKQPTFTIYASGRYTQGIPSSKVRGGMELAFKVTQARVTPMDQVTVMMLNSSEPGSCGLASSWSAGVEQDITPTNGCLALGIRLPHTEYELFRTEHDPKERSLLYIGERPTDGSSPDRPDKRPTSYQAPLVQCAAASEEFPNYYSLKYVGKEGANGSEELKPLPVALLLLIALQLLRWD", "length": 487, "header": "tr|A0A8V0YWH7-1|A0A8V0YWH7_CHICK Computationally mapped isoform of APC down-regulated 1 like OS=Gallus gallus OX=9031 GN=APCDD1L PE=4 SV=1 CANONICAL=A0A8V0YIB9-1" }, "locus": { "chromosome": "20", "start_pos": 11515355, "end_pos": 11511572, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010035532.1", "url": "https://www.ensembl.org/id/ENSGALT00010035532.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020646.1", "url": "https://www.ensembl.org/id/ENSGALP00010020646.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 468, "start_aa": "Thr", "end_pos": 468, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr468", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:419316", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419316", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "Q8NCL9-1", "protein_name": "Protein APCDD1-like", "gene_name": "APCDD1L", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPAAMLPYACVLVLLGAHTAPAAGEAGGSCLRWEPHCQQPLPDRVPSTAILPPRLNGPWISTGCEVRPGPEFLTRAYTFYPSRLFRAHQFYYEDPFCGEPAHSLLVKGKVRLRRASWVTRGATEADYHLHKVGIVFHSRRALVDVTGRLNQTRAGRDCARRLPPARAWLPGALYELRSARAQGDCLEALGLTMHELSLVRVQRRLQPQPRASPRLVEELYLGDIHTDPAERRHYRPTGYQRPLQSALHHVQPCPACGLIARSDVHHPPVLPPPLALPLHLGGWWVSSGCEVRPAVLFLTRLFTFHGHSRSWEGYYHHFSDPACRQPTFTVYAAGRYTRGTPSTRVRGGTELVFEVTRAHVTPMDQVTTAMLNFSEPSSCGGAGAWSMGTERDVTATNGCLPLGIRLPHVEYELFKMEQDPLGQSLLFIGQRPTDGSSPDTPEKRPTSYQAPLVLCHGEAPDFSRPPQHRPSLQKHPSTGGLHIAPFPLLPLVLGLAFLHWL", "length": 501 }, "evidence": [ { "id": "A0A8V0YIB9", "url": "https://omabrowser.org/oma/group/A0A8V0YIB9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIB9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIB9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "Wnt-protein binding", "id": "GO:0017147", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017147", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIB9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIB9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "negative regulation of Wnt signaling pathway", "id": "GO:0030178", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030178", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIB9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIB9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 183, "end_pos": 185, "annotation": "n_glycosylation_sequon" }, { "start_pos": 343, "end_pos": 345, "annotation": "n_glycosylation_sequon" }, { "start_pos": 407, "end_pos": 409, "annotation": "n_glycosylation_sequon" }, { "start_pos": 512, "end_pos": 514, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YIB9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIB9" }, { "id": "SM01352", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM01352" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "APCDD1", "eco_id": "ECO_0000259", "start_pos": 66, "end_pos": 307, "start_aa": "Arg", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 468 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 183, "end_pos": 185 }, { "start_pos": 343, "end_pos": 345 }, { "start_pos": 407, "end_pos": 409 }, { "start_pos": 512, "end_pos": 514 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YIE7-1", "uniprot_ac": "A0A8V0YIE7", "uniprot_id": "A0A8V0YIE7_CHICK", "mass": { "chemical_mass": 197816.0, "monoisotopic_mass": 197816.0 }, "refseq": { "ac": "XP_004940405", "name": "beta/gamma crystallin domain-containing protein 1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004940405" }, "gene_names": [ { "name": "AIM1", "type": "recommended", "evidence": [ { "id": "A0A8V0YIE7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIE7" } ] }, { "name": "AIM1", "type": "synonym", "evidence": [ { "id": "XP_004940405", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004940405" } ] } ], "protein_names": [ { "name": "Crystallin beta-gamma domain containing 1", "type": "synonym", "evidence": [ { "id": "A0A8V0YIE7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIE7/entry#names_and_taxonomy" } ] }, { "name": "beta/gamma crystallin domain-containing protein 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_004940405", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004940405" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052534.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 1, 2022 this sequence version replaced XP_004940405.3. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004940405", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004940405" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIE7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIE7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "AIM1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIE7", "locus": {} } ], "crossref": [ { "id": "cd23464", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd23464", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "421783", "url": "https://www.ncbi.nlm.nih.gov/gene/421783", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000772", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000772", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001064", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001064", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035992", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035992", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050252", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050252", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:421783", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:421783", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WEAMVLT", "url": "https://omabrowser.org/oma/group/WEAMVLT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YIC1", "url": "https://www.orthodb.org/?gene=A0A8V0YIC1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YIE7", "url": "https://www.orthodb.org/?gene=A0A8V0YIE7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YIG8", "url": "https://www.orthodb.org/?gene=A0A8V0YIG8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YJ68", "url": "https://www.orthodb.org/?gene=A0A8V0YJ68", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YL13", "url": "https://www.orthodb.org/?gene=A0A8V0YL13", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YQY4", "url": "https://www.orthodb.org/?gene=A0A8V0YQY4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YR23", "url": "https://www.orthodb.org/?gene=A0A8V0YR23", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YR28", "url": "https://www.orthodb.org/?gene=A0A8V0YR28", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11818", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11818", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11818:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11818:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00030", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00030", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00652", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00652", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_004940405", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004940405", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YIC1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIC1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YIC1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIC1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YIE7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIE7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YIE7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIE7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YIG8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIG8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YIG8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIG8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJ68", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ68", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJ68-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ68-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YL13", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL13", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YL13-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL13-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQY4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQY4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQY4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQY4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YR23", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YR23", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YR23-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YR23-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YR28", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YR28", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YR28-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YR28-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSTASLPAALRKSSSQFPDCSREEHKKKPVLERLGNLFGTGRRKNVKSSLERSSHWKGERSVSPHTAQPVYCKHIQQGPESPPVQKQARNTSVVPETREYSFSGEVGPLYHDTISEWSGRGVSSDSEWSPDWSSSSETIKNSFFESSLNVDTQEPEKGSVTDINNSTTPDFIKSLRNLSSEDLEKSILSHKHLVNTWVSEEPGHAKPKDLPYKLETLASEHPQPARVLTVDIYLRKTEELLNEPVTVISEENCGDSDTMDKKSSSKRSGKRRKSQSSSDIPNGERNQTENTAREDSVFEDDASSEGFPEKVITSERKLKSPQQTPERNSFSSSNNPDLKAGSAHKGTSKTDADKGKQQASNTTPARRRSYKKNQLDAVPTSPTGLKSQVKDYSSKRHPLASTESNPMTKRTLQEKGTLPGAFGEDSLESPKVSSADKAEDNTVVFAEGRNETKTEKHGNDSDGRAFSRTDKIKNGDLCMPAERQTSSDLDSLKLKSLDASRIVTTKISLARTEKNLGRCLQNLLESPAKPKNVELNFKAPTNQDSLESEQDTLEKPVNKNNNSIANKISLFENKCASQSQRPTDISASKNSTVPSTFVGRAKLIFGKQPKESEQPDKTLNKQNSRQKLFENGTAEKDSTAELKGKNEEGSAPYEDIGKGTELKVKAAISLFNQSSKIDASGASLKQPDPELSAVKKESSPFKQSLHSPVKSESVHDISYQQNNTSSELPRNEEKVPPDTEVLSTCNGDKYPLQSRQLCRPESQKVENGDKNAKPGDLTFEAQQYDDNSVNGILVSEHSNNTPESPGKTCNGSTEDDAIFDSPTDMKKFAETIKNLDSSVCLPQKKKRSKLPKSPAPHFAMPPIHEDNLEKVFDPSVFTFGLGLRREKAQDLLPTQQMKMQSLETIARVRPKRASTEQSIIFKALQSCNREEPAFTQEINGKENMDGTDGEVKRSRLEKSSLFSSLLSSASKEKFLNPSVTSVNNATFIADSSGIPSLQQDASGPFILPQKPESLSDMKFPSYMEKYIQADSAKKELSLQIPNYGNPEKNFSSWLGANRYESNVPTGLLDVDTLSRNGQSKINPRPGKLVIYCESDNQENVIEVFHDVLDCSSWVLSPTILVKVIRGCWILYEKPNFEGPSIPLEEGELELPDIWGAGEEQNECGSLKPAVIGSIRHVVKDYRVSQIDLYTEPEGLGIVTSFFDDTEETGVFGSTQKTCSIKVHWGIWLIYEEPGFQGVPLMLEPGEYPNLAFWEKKEAYIRSMRPLKMGGRKVECPGDPKVVIYEKPFFEGRHVEVESEIFTLSDKESEEKTRLSLTSVGSIKVLGGVWVAYEKPGFEGHQYLLEEGEYRDWTDWGGYDEELQSLRPVVGDFTSSHMIMYSEKDFGSKGSNINVLGIVSNLKDTGYGLRTQSINVLSGVWVAYENPEFTGEQYILDKGLYPNIEAWGGKNCKISSVQPIVMDIGGSERGKVKVQLFSEPEFKGNCQILEKNTGCIDSFTVKSSKVLGGSCIVFDQEEFSGNQYVLEEGIYPDLMAMGCSSQAALKSLRIINIELSEPCIALFEKVGFQGRKIEFTTEVLNLQFLGYNPRIASVQVLGGTWIIYEHSNYRGRQMLLSPNEIPDWYKLSGCCQIGSLRPLLQKRVYFRLRNKETGKFMSTDGNLDNLNLLRIQAAEDVDSDDQIWLYQDGFIRCRMAEDCCLTIVGNLITPGSKLGLSFERNEDKQYWHISPDGRIYSKMKPKLVLDIKGGTQYDSDHVVVNTVNEEKLTQCWEPLVV", "length": 1776, "header": "tr|A0A8V0YIE7-1|A0A8V0YIE7_CHICK Isoform 1 of Crystallin beta-gamma domain containing 1 OS=Gallus gallus OX=9031 GN=AIM1 PE=3 SV=1 CANONICAL=A0A8V0YIE7-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YIC1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIE7/entry#A0A8V0YIC1-1", "sequence": { "sequence": "QFPDCSREEHKKKPVLERLGNLFGTGRRKNVKSSLERSSHWKGERSVSPHTAQPVYCKHIQQGPESPPVQKQARNTSVVPETREYSFSGEVGPLYHDTISEWSGRGVSSDSEWSPDWSSSSETIKNSFFESSLNVDTQEPEKGSVTDINNSTTPDFIKSLRNLSSEDLEKSILSHKHLVNTWVSEEPGHAKPKDLPYKVLTVDIYLRKTEELLNEPVTVISEENCGDSDTMDKKSSSKRSGKRRKSQSSSDIPNGERNQTENTAREDSVFEDDASSEGFPEKVITSERKLKSPQQTPERNSFSSSNNPDLKAGSAHKGTSKTDADKGKQQASNTTPARRRSYKKNQLDAVPTSPTGLKSQVKDYSSKRHPLASTESNPMTKRTLQEKGTLPGAFGEDSLESPKVSSADKAEDNTVVFAEGRNETKTENPAKPKNVELNFKAPTNQDSLESEQDTLEKPVNKNNNSIANKISLFENKCASQSQRPTDISASKNSTVPSTFVGRAKLIFGKQPKESEQPDKTLNKQNSRQKLFENGTAEKDSTAELKGKNEEGSAPYEDIGKGTELKVKAAISLFNQSSKIDASGASLKQPDPELSAVKKESSPFKQSLHSPVKSESVHDISYQQNNTSSELPRNEEKVPPDTEVLSTCNGDKYPLQSRQLCRPESQKVENGDKNAKPGDLTFEAQQYDDNSVNGILVSEHSNNTPESPGKTCNGSTEDDAIFDSPTDMKKFAETIKNLDSSVCLPQKKKRSKLPKSPAPHFAMPPIHEDNLEKVFDPSVFTFGLGLRREKAQDLLPTQQMKMQSLETIARVRPKRASTEQSIIFKALQSCNREEPAFTQEINGKENMDGTDGEVKRSRLEKSSLFSSLLSSASKEKFLNPSVTSVNNATFIADSSGIPSLQQDASGPFILPQKPESLSDMKFPSYMEKYIQADSAKKELSLQIPNYGNPEKNFSSWLGANRYESNVPTGLLDVDVSIMSLKIYLEKLSCLTLSRNGQSKINPRPGKLVIYCESDNQENVIEVFHDVLDCSSWVLSPTILVKVIRGCWILYEKPNFEGPSIPLEEGELELPDIWGAGEEQNECGSLKPAVIGSIRHVVKDYRVSQIDLYTEPEGLGIVTSFFDDTEETGVFGSTQKTCSIKVHWGIWLIYEEPGFQGVPLMLEPGEYPNLAFWEKKEAYIRSMRPLKMGGRKVECPGDPKVVIYEKPFFEGRHVEVESEIFTLSDKESEEKTRLSLTSVGSIKVLGGVWVAYEKPGFEGHQYLLEEGEYRDWTDWGGYDEELQSLRPVVGDFTSSHMIMYSEKDFGSKGSNINVLGIVSNLKDTGYGLRTQSINVLSGVWVAYENPEFTGEQYILDKGLYPNIEAWGGKNCKISSVQPIVMVRSQFYLFSEPEFKGNCQILEKNTGCIDSFTVKSSKVLGGSCIVFDQEEFSGNQYVLEEGIYPDLMAMGCSSQAALKSLRIINIELSEPCIALFEKVGFQGRKIEFTTEVLNLQFLGYNPRIASVQVLGGTWIIYEHSNYRGRQMLLSPNEIPDWYKLSGCCQIGSLRPLLQKRVYFRLRNKETGKFMSTDGNLDNLNLLRIQAAEDVDSDDQIWLYQDGFIRCRMAEDCCLTIVGNLITPGSKLGLSFERNEDKQYWHISPDGRIYSKMKPKLVLDIKGGTQYDSDHVVVNTVNEEKLTQCWEPLVV", "length": 1687, "header": "tr|A0A8V0YIC1-1|A0A8V0YIE7_CHICK Computationally mapped isoform of Crystallin beta-gamma domain containing 1 OS=Gallus gallus OX=9031 GN=AIM1 PE=3 SV=1 CANONICAL=A0A8V0YIE7-1" }, "locus": { "chromosome": "3", "start_pos": 67869423, "end_pos": 67827043, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031753.1", "url": "https://www.ensembl.org/id/ENSGALT00010031753.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018585.1", "url": "https://www.ensembl.org/id/ENSGALP00010018585.1" } ] } }, { "isoform_ac": "A0A8V0YIE7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIE7/entry#A0A8V0YIE7-1", "sequence": { "sequence": "MSTASLPAALRKSSSQFPDCSREEHKKKPVLERLGNLFGTGRRKNVKSSLERSSHWKGERSVSPHTAQPVYCKHIQQGPESPPVQKQARNTSVVPETREYSFSGEVGPLYHDTISEWSGRGVSSDSEWSPDWSSSSETIKNSFFESSLNVDTQEPEKGSVTDINNSTTPDFIKSLRNLSSEDLEKSILSHKHLVNTWVSEEPGHAKPKDLPYKLETLASEHPQPARVLTVDIYLRKTEELLNEPVTVISEENCGDSDTMDKKSSSKRSGKRRKSQSSSDIPNGERNQTENTAREDSVFEDDASSEGFPEKVITSERKLKSPQQTPERNSFSSSNNPDLKAGSAHKGTSKTDADKGKQQASNTTPARRRSYKKNQLDAVPTSPTGLKSQVKDYSSKRHPLASTESNPMTKRTLQEKGTLPGAFGEDSLESPKVSSADKAEDNTVVFAEGRNETKTEKHGNDSDGRAFSRTDKIKNGDLCMPAERQTSSDLDSLKLKSLDASRIVTTKISLARTEKNLGRCLQNLLESPAKPKNVELNFKAPTNQDSLESEQDTLEKPVNKNNNSIANKISLFENKCASQSQRPTDISASKNSTVPSTFVGRAKLIFGKQPKESEQPDKTLNKQNSRQKLFENGTAEKDSTAELKGKNEEGSAPYEDIGKGTELKVKAAISLFNQSSKIDASGASLKQPDPELSAVKKESSPFKQSLHSPVKSESVHDISYQQNNTSSELPRNEEKVPPDTEVLSTCNGDKYPLQSRQLCRPESQKVENGDKNAKPGDLTFEAQQYDDNSVNGILVSEHSNNTPESPGKTCNGSTEDDAIFDSPTDMKKFAETIKNLDSSVCLPQKKKRSKLPKSPAPHFAMPPIHEDNLEKVFDPSVFTFGLGLRREKAQDLLPTQQMKMQSLETIARVRPKRASTEQSIIFKALQSCNREEPAFTQEINGKENMDGTDGEVKRSRLEKSSLFSSLLSSASKEKFLNPSVTSVNNATFIADSSGIPSLQQDASGPFILPQKPESLSDMKFPSYMEKYIQADSAKKELSLQIPNYGNPEKNFSSWLGANRYESNVPTGLLDVDTLSRNGQSKINPRPGKLVIYCESDNQENVIEVFHDVLDCSSWVLSPTILVKVIRGCWILYEKPNFEGPSIPLEEGELELPDIWGAGEEQNECGSLKPAVIGSIRHVVKDYRVSQIDLYTEPEGLGIVTSFFDDTEETGVFGSTQKTCSIKVHWGIWLIYEEPGFQGVPLMLEPGEYPNLAFWEKKEAYIRSMRPLKMGGRKVECPGDPKVVIYEKPFFEGRHVEVESEIFTLSDKESEEKTRLSLTSVGSIKVLGGVWVAYEKPGFEGHQYLLEEGEYRDWTDWGGYDEELQSLRPVVGDFTSSHMIMYSEKDFGSKGSNINVLGIVSNLKDTGYGLRTQSINVLSGVWVAYENPEFTGEQYILDKGLYPNIEAWGGKNCKISSVQPIVMDIGGSERGKVKVQLFSEPEFKGNCQILEKNTGCIDSFTVKSSKVLGGSCIVFDQEEFSGNQYVLEEGIYPDLMAMGCSSQAALKSLRIINIELSEPCIALFEKVGFQGRKIEFTTEVLNLQFLGYNPRIASVQVLGGTWIIYEHSNYRGRQMLLSPNEIPDWYKLSGCCQIGSLRPLLQKRVYFRLRNKETGKFMSTDGNLDNLNLLRIQAAEDVDSDDQIWLYQDGFIRCRMAEDCCLTIVGNLITPGSKLGLSFERNEDKQYWHISPDGRIYSKMKPKLVLDIKGGTQYDSDHVVVNTVNEEKLTQCWEPLVV", "length": 1776, "header": "tr|A0A8V0YIE7-1|A0A8V0YIE7_CHICK Isoform 1 of Crystallin beta-gamma domain containing 1 OS=Gallus gallus OX=9031 GN=AIM1 PE=3 SV=1 CANONICAL=A0A8V0YIE7-1" }, "locus": { "chromosome": "3", "start_pos": 67890854, "end_pos": 67827043, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031786.1", "url": "https://www.ensembl.org/id/ENSGALT00010031786.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018606.1", "url": "https://www.ensembl.org/id/ENSGALP00010018606.1" } ] } }, { "isoform_ac": "A0A8V0YIG8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIE7/entry#A0A8V0YIG8-1", "sequence": { "sequence": "MSTASLPAALRKSSSQFPDCSREEHKKKPVLERLGNLFGTGRRKNVKSSLERSSHWKGERSVSPHTAQPVYCKHIQQGPESPPVQKQARNTSVVPETREYSFSGEVGPLYHDTISEWSGRGVSSDSEWSPDWSSSSETIKNSFFESSLNVDTQEPEKGSVTDINNSTTPDFIKSLRNLSSEDLEKSILSHKHLVNTWVSEEPGHAKPKDLPYKLETLASEHPQPARVLTVDIYLRKTEELLNEPVTVISEENCGDSDTMDKKSSSKRSGKRRKSQSSSDIPNGERNQTENTAREDSVFEDDASSEGFPEKVITSERKLKSPQQTPERNSFSSSNNPDLKAGSAHKGTSKTDADKGKQQASNTTPARRRSYKKNQLDAVPTSPTGLKSQVKDYSSKRHPLASTESNPMTKRTLQEKGTLPGAFGEDSLESPKVSSADKAEDNTVVFAEGRNETKTEKHGNDSDGRAFSRTDKIKNGDLCMPAERQTSSDLDSLKLKSLDASRIVTTKISLPAKPKNVELNFKAPTNQDSLESEQDTLEKPVNKNNNSIANKISLFENKCASQSQRPTDISASKNSTVPSTFVGRAKLIFGKQPKESEQPDKTLNKQNSRQKLFENGTAEKDSTAELKGKNEEGSAPYEDIGKGTELKVKAAISLFNQSSKIDASGASLKQPDPELSAVKKESSPFKQSLHSPVKSESVHDISYQQNNTSSELPRNEEKVPPDTEVLSTCNGDKYPLQSRQLCRPESQKVENGDKNAKPGDLTFEAQQYDDNSVNGILVSEHSNNTPESPGKTCNGSTEDDAIFDSPTDMKKFAETIKNLDSSVCLPQKKKRSKLPKSPAPHFAMPPIHEDNLEKVFDPSVFTFGLGLRREKAQDLLPTQQMKMQSLETIARVRPKRASTEQSIIFKALQSCNREEPAFTQEINGKENMDGTDGEVKRSRLEKSSLFSSLLSSASKEKFLNPSVTSVNNATFIADSSGIPSLQQDASGPFILPQKPESLSDMKFPSYMEKYIQADSAKKELSLQIPNYGNPEKNFSSWLGANRYESNVPTGLLDVDTLSRNGQSKINPRPGKLVIYCESDNQENVIEVFHDVLDCSSWVLSPTILVKVIRGCWILYEKPNFEGPSIPLEEGELELPDIWGAGEEQNECGSLKPAVIGSIRHVVKDYRVSQIDLYTEPEGLGIVTSFFDDTEETGVFGSTQKTCSIKVHWGIWLIYEEPGFQGVPLMLEPGEYPNLAFWEKKEAYIRSMRPLKMGGRKVECPGDPKVVIYEKPFFEGRHVEVESEIFTLSDKESEEKTRLSLTSVGSIKVLGGVWVAYEKPGFEGHQYLLEEGEYRDWTDWGGYDEELQSLRPVVGDFTSSHMIMYSEKDFGSKGSNINVLGIVSNLKDTGYGLRTQSINVLSGVWVAYENPEFTGEQYILDKGLYPNIEAWGGKNCKISSVQPIVMDIGGSERGKVKVQLFSEPEFKGNCQILEKNTGCIDSFTVKSSKVLGGSCIVFDQEEFSGNQYVLEEGIYPDLMAMGCSSQAALKSLRIINIELSEPCIALFEKVGFQGRKIEFTTEVLNLQFLGYNPRIASVQVLGGTWIIYEHSNYRGRQMLLSPNEIPDWYKLSGCCQIGSLRPLLQKRVYFRLRNKETGKFMSTDGNLDNLNLLRIQAAEDVDSDDQIWLYQDGFIRCRMAEDCCLTIVGNLITPGSKLGLSFERNEDKQYWHISPDGRIYSKMKPKLVLDIKGGTQYDSDHVVVNTVNEEKLTQCWEPLVV", "length": 1759, "header": "tr|A0A8V0YIG8-1|A0A8V0YIG8_CHICK Computationally mapped isoform of Crystallin beta-gamma domain containing 1 OS=Gallus gallus OX=9031 GN=AIM1 PE=3 SV=1 CANONICAL=A0A8V0YIE7-1" }, "locus": { "chromosome": "3", "start_pos": 67890854, "end_pos": 67827043, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031805.1", "url": "https://www.ensembl.org/id/ENSGALT00010031805.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018621.1", "url": "https://www.ensembl.org/id/ENSGALP00010018621.1" } ] } }, { "isoform_ac": "A0A8V0YJ68-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIE7/entry#A0A8V0YJ68-1", "sequence": { "sequence": "MSSSQFPDCSREEHKKKPVLERLGNLFGTGRRKNVKSSLERSSHWKGERSVSPHTAQPVYCKHIQQGPESPPVQKQARNTSVVPETREYSFSGEVGPLYHDTISEWSGRGVSSDSEWSPDWSSSSETIKNSFFESSLNVDTQEPEKGSVTDINNSTTPDFIKSLRNLSSEDLEKSILSHKHLVNTWVSEEPGHAKPKDLPYKLETLASEHPQPARVLTVDIYLRKTEELLNEPVTVISEENCGDSDTMDKKSSSKRSGKRRKSQSSSDIPNGERNQTENTAREDSVFEDDASSEGFPEKVITSERKLKSPQQTPERNSFSSSNNPDLKAGSAHKGTSKTDADKGKQQASNTTPARRRSYKKNQLDAVPTSPTGLKSQVKDYSSKRHPLASTESNPMTKRTLQEKGTLPGAFGEDSLESPKVSSADKAEDNTVVFAEGRNETKTEKHGNDSDGRAFSRTDKIKNGDLCMPAERQTSSDLDSLKLKSLDASRIVTTKISLPAKPKNVELNFKAPTNQDSLESEQDTLEKPVNKNNNSIANKISLFENKCASQSQRPTDISASKNSTVPSTFVGRAKLIFGKQPKESEQPDKTLNKQNSRQKLFENGTAEKDSTAELKGKNEEGSAPYEDIGKGTELKVKAAISLFNQSSKIDASGASLKQPDPELSAVKKESSPFKQSLHSPVKSESVHDISYQQNNTSSELPRNEEKVPPDTEVLSTCNGDKYPLQSRQLCRPESQKVENGDKNAKPGDLTFEAQQYDDNSVNGILVSEHSNNTPESPGKTCNGSTEDDAIFDSPTDMKKFAETIKNLDSSVCLPQKKKRSKLPKSPAPHFAMPPIHEDNLEKVFDPSVFTFGLGLRREKAQDLLPTQQMKMQSLETIARVRPKRASTEQSIIFKALQSCNREEPAFTQEINGKENMDGTDGEVKRSRLEKSSLFSSLLSSASKEKFLNPSVTSVNNATFIADSSGIPSLQQDASGPFILPQKPESLSDMKFPSYMEKYIQADSAKKELSLQIPNYGNPEKNFSSWLGANRYESNVPTGLLDVDTLSRNGQSKINPRPGKLVIYCESDNQENVIEVFHDVLDCSSWVLSPTILVKVIRGCWILYEKPNFEGPSIPLEEGELELPDIWGAGEEQNECGSLKPAVIGSIRHVVKDYRVSQIDLYTEPEGLGIVTSFFDDTEETGVFGSTQKTCSIKVHWGIWLIYEEPGFQGVPLMLEPGEYPNLAFWEKKEAYIRSMRPLKMGGRKVECPGDPKVVIYEKPFFEGRHVEVESEIFTLSDKESEEKTRLSLTSVGSIKVLGGVWVAYEKPGFEGHQYLLEEGEYRDWTDWGGYDEELQSLRPVVGDFTSSHMIMYSEKDFGSKGSNINVLGIVSNLKDTGYGLRTQSINVLSGVWVAYENPEFTGEQYILDKGLYPNIEAWGGKNCKISSVQPIVMDIGGSERGKVKVQLFSEPEFKGNCQILEKNTGCIDSFTVKSSKVLGGSCIVFDQEEFSGNQYVLEEGIYPDLMAMGCSSQAALKSLRIINIELSEPCIALFEKVGFQGRKIEFTTEVLNLQFLGYNPRIASVQVLGGTWIIYEHSNYRGRQMLLSPNEIPDWYKLSGCCQIGSLRPLLQKRVYFRLRNKETGKFMSTDGNLDNLNLLRIQAAEDVDSDDQIWLYQDGFIRCRMAEDCCLTIVGNLITPGSKLGLSFERNEDKQYWHISPDGRIYSKMKPKLVLDIKGGTQYDSDHVVVNTVNEEKLTQCWEPLVV", "length": 1748, "header": "tr|A0A8V0YJ68-1|A0A8V0YJ68_CHICK Computationally mapped isoform of Crystallin beta-gamma domain containing 1 OS=Gallus gallus OX=9031 GN=AIM1 PE=3 SV=1 CANONICAL=A0A8V0YIE7-1" }, "locus": { "chromosome": "3", "start_pos": 67875804, "end_pos": 67827043, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031783.1", "url": "https://www.ensembl.org/id/ENSGALT00010031783.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018604.1", "url": "https://www.ensembl.org/id/ENSGALP00010018604.1" } ] } }, { "isoform_ac": "A0A8V0YL13-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIE7/entry#A0A8V0YL13-1", "sequence": { "sequence": "MDKKSSSKRSGKRRKSQSSSDIPNGERNQTENTAREDSVFEDDASSEGFPEKVITSERKLKSPQQTPERNSFSSSNNPDLKAGSAHKGTSKTDADKGKQQASNTTPARRRSYKKNQLDAVPTSPTGLKSQVKDYSSKRHPLASTESNPMTKRTLQEKGTLPGAFGEDSLESPKVSSADKAEDNTVVFAEGRNETKTEKHGNDSDGRAFSRTDKIKNGDLYVTVYLFASYSPAKPKNVELNFKAPTNQDSLESEQDTLEKPVNKNNNSIANKISLFENKCASQSQRPTDISASKNSTVPSTFVGRAKLIFGKQPKESEQPDKTLNKQNSRQKLFENGTAEKDSTAELKGKNEEGSAPYEDIGKGTELKVKAAISLFNQSSKIDASGASLKQPDPELSAVKKESSPFKQSLHSPVKSESVHDISYQQNNTSSELPRNEEKVPPDTEVLSTCNGDKYPLQSRQLCRPESQKVENGDKNAKPGDLTFEAQQYDDNSVNGILVSEHSNNTPESPGKTCNGSTEDDAIFDSPTDMKKFAETIKNLDSSVCLPQKKKRSKLPKSPAPHFAMPPIHEDNLEKVFDPSVFTFGLGLRREKAQDLLPTQQMKMQSLETIARVRPKRASTEQSIIFKALQSCNREEPAFTQEINGKENMDGTDGEVKRSRLEKSSLFSSLLSSASKEKFLNPSVTSVNNATFIADSSGIPSLQQDASGPFILPQKPESLSDMKFPSYMEKYIQADSAKKELSLQIPNYGNPEKNFSSWLGANRYESNVPTGLLDVDVSIMSLKIYLEKLSCLAFVLFPFTLSRNGQSKINPRPGKLVIYCESDNQENVIEVFHDVLDCSSWVLSPTILVKVIRGCWILYEKPNFEGPSIPLEEGELELPDIWGAGEEQNECGSLKPAVIGSIRHVVKDYRVSQIDLYTEPEGLGIVTSFFDDTEETGVFGSTQKTCSIKVHWGIWLIYEEPGFQGVPLMLEPGEYPNLAFWEKKEAYIRSMRPLKMVKYHYYLPVVIYEKPFFEGRHVEVESEIFTLSDKESEEKTRLSLTSVGSIKVLGGVWVAYEKPGFEGHQYLLEEGEYRDWTDWGGYDEELQSLRPVVGDFTSSHMIMYSEKDFGSKGSNINVLGIVSNLKDTGYGLRTQSINVLSGVWVAYENPEFTGEQYILDKGLYPNIEAWGGKNCKISSVQPIVMVRSQFYLFSEPEFKGNCQILEKNTGCIDSFTVKSSKVLGGSCIVFDQEEFSGNQYVLEEGIYPDLMAMGCSSQAALKSLRIINIELSEPCIALFEKVGFQGRKIEFTTEVLNLQFLGYNPRIASVQVLGGTWIIYEHSNYRGRQMLLSPNEIPDWYKLSGCCQIGSLRPLLQKRVYFRLRNKETGKFMSTDGNLDNLNLLRIQAAEDVDSDDQIWLYQDGFIRCRMAEDCCLTIVGNLITPGSKLGLSFERNEDKQYWHISPDGRIYSKMKPKLVLDIKGGTQYDSDHVVVNTVNEEKLTQCWEPLVV", "length": 1492, "header": "tr|A0A8V0YL13-1|A0A8V0YL13_CHICK Computationally mapped isoform of Crystallin beta-gamma domain containing 1 OS=Gallus gallus OX=9031 GN=AIM1 PE=3 SV=1 CANONICAL=A0A8V0YIE7-1" }, "locus": { "chromosome": "3", "start_pos": 67868694, "end_pos": 67827043, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031721.1", "url": "https://www.ensembl.org/id/ENSGALT00010031721.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018569.1", "url": "https://www.ensembl.org/id/ENSGALP00010018569.1" } ] } }, { "isoform_ac": "A0A8V0YQY4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIE7/entry#A0A8V0YQY4-1", "sequence": { "sequence": "ELLNEPVTVISEENCGDSDTMDKKSSSKRSGKRRKSQSSSDIPNGERNQTENTAREDSVFEDDASSEGFPEKVITSERKLKSPQQTPERNSFSSSNNPDLKAGSAHKGTSKTDADKGKQQASNTTPARRRSYKKNQLDAVPTSPTGLKSQVKDYSSKRHPLASTESNPMTKRTLQEKGTLPGAFGEDSLESPKVSSRQTSSDLDSLKLKSLDASRIVTTKISLPAKPKNVELNFKAPTNQDSLESEQDTLEKPVNKNNNSIANKISLFENKCASQSQRPTDISASKNSTVPSTFVGRAKLIFGKQPKESEQPDKTLNKQNSRQKLFENGTAEKDSTAELKGKNEEGSAPYEDIGKGTELKVKAAISLFNQSSKIDASGASLKQPDPELSAVKKESSPFKQSLHSPVKSESVHDISYQQNNTSSELPRNEEKVPPDTEVLSTCNGDKYPLQSRQLCRPESQKVENGDKNAKPGDLTFEAQQYDDNSVNGILVSEHSNNTPESPGKTCNGSTEDDAIFDSPTDMKKFAETIKNLDSSVCLPQKKKRSKLPKSPAPHFAMPPIHEDNLEKVFDPSVFTFGLGLRREKAQDLLPTQQMKMQSLETIARVRPKRASTEQSIIFKALQSCNREEPAFTQEINGKENMDGTDGEVKRSRLEKSSLFSSLLSSASKEKFLNPSVTSVNNATFIADSSGIPSLQQDASGPFILPQKPESLSDMKFPSYMEKYIQADSAKKELSLQIPNYGNPEKNFSSWLGANRYESNVPTGLLDVDVSIMSLKIYLEKNGQSKINPRPGKLVIYCESDNQENVIEVFHDVLDCSSWVLSPTILVKVIRGCWILYEKPNFEGPSIPLEEGELELPDIWGAGEEQNECGSLKPAVIGSIRHVVKDYRVSQIDLYTEPEGLGIVTSFFDDTEETGVFGSTQKTCSIKVHWGIWLIYEEPGFQGVPLMLEPGEYPNLAFWEKKEAYIRSMRPLKMVKYHYYLPVVIYEKPFFEGRHVEVESEIFTLSDKESEEKTRLSLTSVGSIKVLGGVWVAYEKPGFEGHQYLLEEGEYRDWTDWGGYDEELQSLRPVVGDFTSSHMIMYSEKDFGSKGSNINVLGIVSNLKDTGYGLRTQSINVLSGVWVAYENPEFTGEQYILDKGLYPNIEAWGGKNCKISSVQPIVMVRSQFYLFSEPEFKGNCQILEKNTGCIDSFTVKSSKVLGGSCIVFDQEEFSGNQYVLEEGIYPDLMAMGCSSQAALKSLRIINIVTLFFFFLSFFPHRWIIYEHSNYRGRQMLLSPNEIPDWYKLSGCCQIGSLRPLLQKRVYFRLRNKETGKFMSTDGNLDNLNLLRIQAAEDVDSDDQIWLYQDGFIRCRMAEDCCLTIVGNLITPGSKLGLSFERNEDKQYWHISPDGRIYSKMKPKLVLDIKGGTQYDSDHVVVNTVNEEKLTQCWEPLVV", "length": 1437, "header": "tr|A0A8V0YQY4-1|A0A8V0YQY4_CHICK Computationally mapped isoform of Crystallin beta-gamma domain containing 1 OS=Gallus gallus OX=9031 GN=AIM1 PE=3 SV=1 CANONICAL=A0A8V0YIE7-1" }, "locus": { "chromosome": "3", "start_pos": 67868754, "end_pos": 67827043, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031737.1", "url": "https://www.ensembl.org/id/ENSGALT00010031737.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018577.1", "url": "https://www.ensembl.org/id/ENSGALP00010018577.1" } ] } }, { "isoform_ac": "A0A8V0YR23-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIE7/entry#A0A8V0YR23-1", "sequence": { "sequence": "MSTASLPAALRKSSSQFPDCSREEHKKKPVLERLGNLFGTGRRKNVKSSLERSSHWKGERSVSPHTAQPVYCKHIQQGPESPPVQKQARNTSVVPETREYSFSGEVGPLYHDTISEWSGRGVSSDSEWSPDWSSSSETIKNSFFESSLNVDTQEPEKGSVTDINNSTTPDFIKSLRNLSSEDLEKSILSHKHLVNTWVSEEPGHAKPKDLPYKLETLASEHPQPARVLTVDIYLRKTEELLNEPVTVISEENCGDSDTMDKKSSSKRSGKRRKSQSSSDIPNGERNQTENTAREDSVFEDDASSEGFPEKVITSERKLKSPQQTPERNSFSSSNNPDLKAGSAHKGTSKTDADKGKQQASNTTPARRRSYKKNQLDAVPTSPTGLKSQVKDYSSKRHPLASTESNPMTKRTLQEKGTLPGAFGEDSLESPKVSSADKAEDNTVVFAEGRNETKTEKHGNDSDGRAFSRTDKIKNGDLCMPAERQTSSDLDSLKLKSLDASRIVTTKISLPAKPKNVELNFKAPTNQDSLESEQDTLEKPVNKNNNSIANKISLFENKCASQSQRPTDISASKNSTVPSTFVGRAKLIFGKQPKESEQPDKTLNKQNSRQKLFENGTAEKDSTAELKGKNEEGSAPYEDIGKGTELKVKAAISLFNQSSKIDASGASLKQPDPELSAVKKESSPFKQSLHSPVKSESVHDISYQQNNTSSELPRNEEKVPPDTEVLSTCNGDKYPLQSRQLCRPESQKVENGDKNAKPGDLTFEAQQYDDNSVNGILVSEHSNNTPESPGKTCNGSTEDDAIFDSPTDMKKFAETIKNLDSSVCLPQKKKRSKLPKSPAPHFAMPPIHEDNLEKVFDPSVFTFGLGLRREKAQDLLPTQQMKMQSLETIARVRPKRASTEQSIIFKALQSCNREEPAFTQEINGKENMDGTDGEVKRSRLEKSSLFSSLLSSASKEKFLNPSVTSVNNATFIADSSGIPSLQQDASGPFILPQKPESLSDMKFPSYMEKYIQADSAKKELSLQIPNYGNPEKNFSSWLGANRYESNPHIITTLSLFVLRSHDTTTDFLYSLYHSSLNGQSKINPRPGKLVIYCESDNQENVIEVFHDVLDCSSWVLSPTILVKVIRGCWILYEKPNFEGPSIPLEEGELELPDIWGAGEEQNECGSLKPAVIGSIRHVVKDYRVSQIDLYTEPEGLGIVTSFFDDTEETGVFGSTQKTCSIKVHWGIWLIYEEPGFQGVPLMLEPGEYPNLAFWEKKEAYIRSMRPLKMGGRKVECPGDPKVVIYEKPFFEGRHVEVESEIFTLSDKESEEKTRLSLTSVGSIKVLGGVWVAYEKPGFEGHQYLLEEGEYRDWTDWGGYDEELQSLRPVVGDFTSSHMIMYSEKDFGSKGSNINVLGIVSNLKDTGYGLRTQSINVLSGVWVAYENPEFTGEQYILDKGLYPNIEAWGGKNCKISSVQPIVMVRSQFYLFSEPEFKGNCQILEKNTGCIDSFTVKSSKVLGGSCIVFDQEEFSGNQYVLEEGIYPDLMAMGCSSQAALKSLRIINIELSEPCIALFEKVGFQGRKIEFTTEVLNLQFLGYNPRIASVQVLGGTWIIYEHSNYRGRQMLLSPNEIPDWYKLSGCCQIGSLRPLLQKRVYFRLRNKETGKFMSTDGNLDNLNLLRIQAAEDVDSDDQIWLYQDGFIRCRMAEDCCLTIVGNLITPGSKLGLSFERNEDKQYWHISPDGRIYSKMKPKLVLDIKGGTQYDSDHVVVNTVNEEKLTQCWEPLVCNVYTV", "length": 1774, "header": "tr|A0A8V0YR23-1|A0A8V0YR23_CHICK Computationally mapped isoform of Crystallin beta-gamma domain containing 1 OS=Gallus gallus OX=9031 GN=AIM1 PE=3 SV=1 CANONICAL=A0A8V0YIE7-1" }, "locus": { "chromosome": "3", "start_pos": 67890854, "end_pos": 67826620, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031796.1", "url": "https://www.ensembl.org/id/ENSGALT00010031796.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018613.1", "url": "https://www.ensembl.org/id/ENSGALP00010018613.1" } ] } }, { "isoform_ac": "A0A8V0YR28-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIE7/entry#A0A8V0YR28-1", "sequence": { "sequence": "MSTASLPAALRKSSSQFPDCSREEHKKKPVLERLGNLFGTGRRKNVKSSLERSSHWKGERSVSPHTAQPVYCKHIQQGPESPPVQKQARNTSVVPETREYSFSGEVGPLYHDTISEWSGRGVSSDSEWSPDWSSSSETIKNSFFESSLNVDTQEPEKGSVTDINNSTTPDFIKSLRNLSSEDLEKSILSHKHLVNTWVSEEPGHAKPKDLPYKLETLASEHPQPARVLTVDIYLRKTEELLNEPVTVISEENCGDSDTMDKKSSSKRSGKRRKSQSSSDIPNGERNQTENTAREDSVFEDDASSEGFPEKVITSERKLKSPQQTPERNSFSSSNNPDLKAGSAHKGTSKTDADKGKQQASNTTPARRRSYKKNQLDAVPTSPTGLKSQVKDYSSKRHPLASTESNPMTKRTLQEKGTLPGAFGEDSLESPKVSSADKAEDNTVVFAEGRNETKTEKHGNDSDGRAFSRTDKIKNGDLCMPAERQTSSDLDSLKLKSLDASRIVTTKISLPAKPKNVELNFKAPTNQDSLESEQDTLEKPVNKNNNSIANKISLFENKCASQSQRPTDISASKNSTVPSTFVGRAKLIFGKQPKESEQPDKTLNKQNSRQKLFENGTAEKDSTAELKGKNEEGSAPYEDIGKGTELKVKAAISLFNQSSKIDASGASLKQPDPELSAVKKESSPFKQSLHSPVKSESVHDISYQQNNTSSELPRNEEKVPPDTEVLSTCNGDKYPLQSRQLCRPESQKVENGDKNAKPGDLTFEAQQYDDNSVNGILVSEHSNNTPESPGKTCNGSTEDDAIFDSPTDMKKFAETIKNLDSSVCLPQKKKRSKLPKSPAPHFAMPPIHEDNLEKVFDPSVFTFGLGLRREKAQDLLPTQQMKMQSLETIARVRPKRASTEQSIIFKALQSCNREEPAFTQEINGKENMDGTDGEVKRSRLEKSSLFSSLLSSASKEKFLNPSVTSVNNATFIADSSGIPSLQQDMNNILRGCISWINYMKFPSYMEKYIQADSAKKELSLQIPNYGNPEKNFSSWLGANRYESNVPTGLLDVDVSIMSLKIYLEKNGQSKINPRPGKLVIYCESDNQENVIEVFHDVLDCSSWVLSPTILVKVIRGCWILYEKPNFEGPSIPLEEGELELPDIWGAGEEQNECGSLKPAVIGSIRHVVKDYRVSQIDLYTEPEGLGIVTSFFDDTEETGVFGSTQKTCSIKVHWGIWLIYEEPGFQGVPLMLEPGEYPNLAFWEKKEAYIRSMRPLKMGGRKVECPGDPKVVIYEKPFFEGRHVEVESEIFTLSDKESEEKTRLSLTSVGSIKVLGGVWVAYEKPGFEGHQYLLEEGEYRDWTDWGGYDEELQSLRPVVGDFTSSHMIMYSEKDFGSKGSNINVLGIVSNLKDTGYGLRTQSINVLSGVWVAYENPEFTGEQYILDKGLYPNIEAWGGKNCKISSVQPIVMVRSQFYLFSEPEFKGNCQILEKNTGCIDSFTVKSSKVLGGSCIVFDQEEFSGNQYVLEEGIYPDLMAMGCSSQAALKSLRIINIELSEPCIALFEKVGFQGRKIEFTTEVLNLQFLGYNPRIASVQVLGGTWIIYEHSNYRGRQMLLSPNEIPDWYKLSGCCQIGSLRPLLQKRVYFRLRNKETGKFMSTDGNLDNLNLLRIQAAEDVDSDDQIWLYQDGFIRCRMAEDCCLTIVGNLITPGSKLGLSFERNEDKQYWHISPDGRIYSKMKPKLVLDIKGGTQYDSDHVVVNTVNEEKLTQCWEPLVCNVYTV", "length": 1763, "header": "tr|A0A8V0YR28-1|A0A8V0YR28_CHICK Computationally mapped isoform of Crystallin beta-gamma domain containing 1 OS=Gallus gallus OX=9031 GN=AIM1 PE=3 SV=1 CANONICAL=A0A8V0YIE7-1" }, "locus": { "chromosome": "3", "start_pos": 67890854, "end_pos": 67826620, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031801.1", "url": "https://www.ensembl.org/id/ENSGALT00010031801.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018618.1", "url": "https://www.ensembl.org/id/ENSGALP00010018618.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:421783", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:421783", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2JG52-1", "protein_name": "Crystallin beta-gamma domain containing 1", "gene_name": "Crybg1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPLSPPSQGDPREASPSKAPKKHPTFHIWRSKKKQSPSSSCGVFIPHPPGAFGETRAFLVPDGSQGEPQELTLHGGELQLSDTPSEVPGPSSTESAMLKKSRAQPPEDTRRKPVLEKLGTLFTAGRRRNTRNGLESPTNSNSKSASAKVPKTGSEKTKAQDNQLKATDAGEAGPRQEAEGQPVESCVQATPCDAEQSPCSSINVGVVQQCHSNDSAQLEPLQAEGETFPDATTAAKELLHSSPGNRSRQESAETPARSPGEEALPGAGLQPETARGVSGSPPEEHLVGGVGEAPDGAPGVGAEAGSLGAPGDAVPPGEPPAQDAETSRTAGSVDRAHPTKVLTLDIYLSKTEVAQVDEPASIAPGTDDCEDSDDMEKRSSGRRSGRRRKSQKSTDSPGADAVAPESAAKDEAVFDDEVAPDAAAENCLAERKVKSVQAVPDGGAAPVACPEPKASSCPRGQPRGEPDRSKPLSPTKRKGRSRVPEAVPSSPGSGSRAPAKESPPKRAPAAADSGEEAGRVVPRELTVKSSSLLPEIKPEHKRGPLPHHFDSRGDGGRSRGTGASDADGLKPRNQFGVGRSTVTTKVTLPARPKHVELNLKTPKNPDSLGNEHNSFSQPVHKGNTANKISLFENKRANSSPRHPDVRNTRNNPPSSKTFVGRAKLNLAKKAKEMEQPEKKAVSTSHQNGLVVKEPSAEGKGTAVPVPREEIRPATRGGEGESTKDQVLRPEPEQSDKLDVQTDTAYPSHPGPTALVPVKDSELSGEGQPEAADSKGPVLNNTSDVAQDIAAICDAREAPPKPQDAFSDSQPASAAESARESSLPPSAPISVDAPQDGCVQVPICSVPCTALEVSENHNGCVSPVSPHTEKTPISKPGVGEASPPSTPEHSPETMGKDCPSKVLVQVRSFVLPVENPQDVSSQVISESSEVREAQLPSCHSNEPEVVSVTTCVPQHEDAPDTSPKDIHHREGHVAQSRPHITQSGPEKAPPIQSSSGMPQTAEFILTHSPSSRSHAEGPQRPGQDATSPLTPTRLLNISAGSDNSVLDSSSDMEKFTEIIKKMDSAVCVPQKKKKARVPNSPAPHFAMPPIHEDSLEKVFDPNVFTIGLGKKKESLAEVSPALHLLQNHDPISKLRAKRASTEQSIVFKSLHTNSNGKSEPQTTSEASDKENRDINSGGVKRSRLENSTLFSSMLSSLPQDKVFSPSVTSVNTMSTSFSTSQNSSVSQSSVVQPRKEGGLPCGSDKEQPHLAPHNSLKVFNFNSSNTSRLGSSHMEKYPQKEGSKEDVNSQGNLQLPENNLSDLPKLKNSDGVEGILKSNLPNVGSVDADFLGLFKASRYDPGHSFSGMSLSDSMTLRGSMHSKLNPRPGKVVIFSEPDVSEECIEVFGDIQDCSSWRLSPVIVVKVVRGCWILYEKANFEGHSLALEEGELELSSIWGTEEMLDEEAESDKPVVIGSIRHVVQDYRISQIDLFTEPEGLGLLNSYFDDTEEMQGFPVMQKTCSIKVHWGTWLIYEEPGFQGVPFILEPGEYPDLSFWDTEEAYIGSMRPLKMGGRKVEFPTDPKVVIYEKPSFEGRCMELETEMSSFIMEGGETEETTGNNNLPFTSVGSMKVLRGVWVAYEKCGFTGHQYLLEEGEYRDWNAWGGYNGELQSLRPILSDFSNAHMIMYSEKNFGSKGSSIDVLGIVANLKETGYGVKTQSINVLSGVWVAYENPDFTGEQYVLDKGFYTSFEDWGGKNCKISSVQPICLDSFTGPRRRNQIHLFSEPQFQGQSQSFEETIDQIDDSFQTKSCRVLGGSWVAYDGENFSGNQYVLEEGHYPCLSAMGCLPGATLKSLRFIDFEFSEPTIILFERENFKGKKIELNAETVNLRSLGFNTQIRSVRVVGGIWVTYEYGNYRGRQFLLSPAEVPNWYEFSACRQIGSLRPFAQKRIYFRLRNKATGLFMSTNGNLEDLKLLRVQVMEDVGADDQIWIYQEGCIKCRIAEDCCLTIVGSLVTSGSKLGLALDQNVDSQFWCMKSDGRIYSKMKPNLVLDVKGGAQYDQNHIILNTVSTEKLTQVWEAMVL", "length": 2065 }, "evidence": [ { "id": "A0A8V0YIE7", "url": "https://omabrowser.org/oma/group/A0A8V0YIE7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3ZD79-1", "protein_name": "Crystallin beta-gamma domain containing 1", "gene_name": "Crybg1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPLSPPSQGDSREASPSKPPKKHPTFHLWRSKKKQSPSSSCGVFIPHPPGALGEIRAFIVHDGNPGEPQELTLHGGEPQLSDTPSEVPGPSSTESAMLKKSRAQPPEDTRRKPVLGKLGTLFTAGRRRNTRNGLESPTNSNSKSASAKVPETESEKSKAQGNQLKPTDAGEAGEAGEAGSRQEAEGQSAESSVQATPCDAGPSPCSSIKVGVVQQCLCNDSAQLEPLQAEGETFPDATTAAKELLHSSPGNRSGQESAETPARSPGEDALPGAGLQREAARGVSGSPPEEHLVGGVGEAPDGAPGVGSEAGSLGDPGDAVPPGEPPAQGAETSGTAGPADRAHPTKVLKLDIYLSKTEVAQVAEPASIAPGTDDCCEDSDDMEKRSSGRRSGRRRKSQKSTDSPGADAVAPESAAKDDAVFDDEVAPDAAAENCTAERKVKSVQAVPDGGSASVASPEPKPSACPRGQPRAEPDRAKPQSPTKRKGRSRVPEAVPSSPGSGSRAPAKESPPKRAPAAADGGEEAGRVVPRELTVKSSSLLPEIKPEHKRGPLPHHFGDSRADAGRSRESSRGTGASDADGLKPRNQFGVGRSTVTTKVTLPARPKHVELNLKTPKNPDGLGNEHNPFSQPVHKGNTANKISLFENKRASSSPRHPDVRNTRNNPPSNKTFVGRAKLNLAKKAKEMEQPEKKAMSTSLQNGQVTKGPSAEGKNTDVPIAGEEILPATPAKDQVLCPEPDQSDKLDVQTGTACPPQPAPPALVPEKDPELPREGHPEAADSQSPVLVLNNTNDPAQNITALHDARESPPKPQGTFSDSQPASESSRESPLPPSAPMPVDAPQDGCVQVPMCNVPYTALEVSENHDGCAVPVSPHAEKTPVTKPGGREASPPSTPEHCPETMGKECPSKVLVQVRSFVLPVENPQDVSSHVIAESSEVREVQLPSCHSNEPEVVSVTACGPQHEDTPDTSPKDTHHAEERVSQSRPHIAQPEPEKDLPIEAQSESTGTPLTVGFSPSHSPSSRSHPEGLQRPGPSMTSPLTPAGLLNVSASSDDSVLDSSSDMEKFTEIIKKMDSAVCVPQKKKKSRVPNSPTPHFAMPPIHEDSLEKVFDPNVFTIGLGKKKENQPEVSPALQLLQNHDPISKLRAKRASTEQSIVFKSLHANGNGKGEPQTTSEANDKENRDINSGGVKRSRLEKSTLFSSMLSSLPQDKVFSPSVTSVHTMSTSFSTSRNSSVSQSSVVQPRKEGDLPCGSDKEQSQLAPHDSLKVFNFNSSSTSHLGLRSPGHMEKCPPKEESKEGVSSRGSLPLPENSLSDLTKLKNSDAVESVLKSNLPNVGSVDTDFLGLFKASRYDPGLSFSAMSLSDSMTLRGSMHNKLNPRPGKVVIFSEPDVSEECIEVFGDIQDCSSWSLSPVVLVKVVRGCWILYEKANFEGHSLALEEGELELSNLWGTEDILDEEAESDKPVVIGSIRHVVQDYRISQIDLFTEPDGLGLLNSYFDDTEEMQGFGVMQKTCSIKVHWGTWLIYEEPGFQGIPYILEQGEYPDLSFWDTEEAYIGSMRPLKMGGRKVEFPTDPKVVIYEKPSFQGRCMELETEMCGLVTEGGETEETTGKETNGNVPFTSVGSMKVLRGVWVAYEKCGFTGHQYLLEEGEYRDWNAWGGYSAELQSLRPILSDFSNAHMIMYSEKNFGSKGSSIDVLGIVANLKETGYGVKTQSINVLSGVWVAYENPDFTGEQYVLDKGFYTSFEDWGGKNCKISSVQPICLDSFTGPRRRNQICLFSEPQFQGQSQSFEETAGQIGDSFQTKSCRVLGGSWVAYDGENFSGNQYVLEEGHYPCLSAMGCLPGATLKSLRFIDFEFSEPTIILFERENFKGKKIELNAETVNLRSLGFNPQIRSVRVVGGIWVTYEYGNYRGRQFLLSPAEVPNWYEFSACRQIGSLRPFAQKRIYFRLRNKATGLFMSTNGNLEDLKLLRVQVMEDVGADDQIWIYQDGCIKCRIAEDCCLTIVGSLVTSGSKLGLALDQNVDSQFWCMKSDGRIYSKLKPNLVLDVKGGAQYDQNHIILNTVNTEKLTQVWEAMVL", "length": 2080 }, "evidence": [ { "id": "A0A8V0YIE7", "url": "https://omabrowser.org/oma/group/A0A8V0YIE7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E1BH02-1", "protein_name": "Crystallin beta-gamma domain containing 1", "gene_name": "CRYBG1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSRAQPPEENKRKPVLGKLGTLFTAGRRRNSRNGLESPTSSNTKPGSPKEVTSSRLPERETEKSQPLSGQPTPTDACEEGSPQEKCQEPEGEHPEGCVQAAPPDAKRSPGRGSHAAAAVQQGGESDSPQLEPLEAEGETFPDATATAEQLHSSLENSSKRENAEALIRSPGEDASPGAGREQEPTQGSRGVPGSPAGEHPADGAPRLCAHRGSPEPQGGLSQAPEDSSAPPGDPLAEGAENRAGSAPVNVKAEPPGQDCRPRERAHPAKVLTLDIYLSKTEAAQVDEPVVISPGAGDCGDCDDMEKRSSGRRSGRRRRSQRSTDSPGADPPLPDCEPRDDTVFEDEVAPDAAAENGCAEKKVKSPPQAAPNGGVASAAGLESKSSPSPKGQLRGEPERSKQPPPASSPTKRRGRSRVPEAVPTSPAGGPRPTAKDSPLKRAPDPVPSPAAKESGEEAARVIPRELTVKSSSLLPEIKPEHKRGPLPHLLDGRGDGGRSRDLGRSAGGSDAFEGLKPRNHFGVGRSTVTTKVTLPARPKHVELNLKNSKNLDSLGSEHNPFSQPVHKGNTATKISLFENKRANSSPRHTDIRGLKNTPASNKTFVERAKLNLAKKAKEMELPEKKVMPNSHQNGVPGKLSSAEAKVMLPEEETPVSQLSQGDKVVVQTDAGCPSEPVVAALTPVKDQEILGENDSKAANSKRLELENMTNMAENTPAILDTKDPPPTAIPNPQPGFSDSQPPAESSNGPSLSLAAPIPADDTKDTCAQAPVSSSLCTDLRESESHNGCTLPVSHHNNETMPPSKLAGGREGGGETSPPLSPEHSPQAVGDECPSKVLVQVRSFMLPVESMEGVCSQIITESSEVREAQLPSCHNNELQVVSVASGAPQKEEVQGNKGTSPKHIHCKEEHIVKSGAQVMPPESEATLPVQAQSEDNEKPLKAESTATSLPDNRSHLETPQRPSQSAVNGQGSPASLLNISAGSDDSVFDSSSDMEKFTEIIKKMDSTVCMPQKKKKTRLPNSPAPHFAMPPIHEDNLEKVFDPNVFTFGLGKKKEGQLEMSPALHLMQNLDTKSKLRPKRSSTEQSVLFKSLQTHTNGKDEPLAAPEVNDKENKDVQNGGVKRSRLEKSALFSSLLSSLPQDKIFSPSVTSVNTMTTSFGTAHSSSLSRPSVLQPVAESAPPCSTEKEQPSLPASNLKVFNFNSSDTSHSALKSLSPMEKCPQKEETKKDLDLQSNLPMSETKFSEFSKLKTNGDTSNHTESVLKSNLPSYGSSDTDFTGLFKASRFDPSISFSGMALSDTTTIRGSVQNKINPRPGKVVIYSEPDISEACIEVFSDVEDCSTWSLSPVILVKVVRGCWILYEKPNFEGHSIPLEEGELELSGLWGIEDILERNEDEAVSTKPMVIGSIRLVVQDYRVSQIDLFTEPEGLGLLNSYFDDTEEMQGFGIIQKTCSIKVHWGTWLIYEEPGFQGVPFILEPGEYPDLSFWDTEEAYIGSMRPLKMGGRKVEFPTDPKVVIYEKPFFEGKCMELETEMGRFIMEGGETEETTGDEHLSFVSVGSMKVLRGIWVAYEKPDFTGHQYLLEEGEYKDWNDWGGYSGELQSLRPILGDFSNAHMIMYSEKNFGSKGSSIDVLGIVANLKETGYGVKTQSINVLSGVWVAYENPDFTGEQYILDKGFYTSFEDWGGKNCKISSVQPICLDSFTGPRRRNQIHLFSEPHFQGCSQCFGETTSQIDDSFSTKSCRVLGGSWVAYDGENFSGNQYVLEEGHYPSLSAMGCHPGATFKSLRFIDVEFSEPTIILFEREDFKGKKIEFNTEIVNLRSLGFNTHIRSVQVIGGIWVTYEYGNYRGRQFLLSPAEVPKWYEFSGCHQIGSLRPFVQKRIYFRLRNKATGLFMSTNGNLEDLKLLRIQVMEDVGADDQIWIYQEGCIKCRIAEDCCLTISGSLVTSGSKLGLALEQNADSQFWSMKPDGRIYSKLKPNLVLDIKGGTQYDQNHLILNTVSKEKLTQVWEAMVL", "length": 2015 }, "evidence": [ { "id": "A0A8V0YIE7", "url": "https://omabrowser.org/oma/group/A0A8V0YIE7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 1049, "end_pos": 1051, "annotation": "n_glycosylation_sequon" }, { "start_pos": 164, "end_pos": 166, "annotation": "n_glycosylation_sequon" }, { "start_pos": 165, "end_pos": 167, "annotation": "n_glycosylation_sequon" }, { "start_pos": 177, "end_pos": 179, "annotation": "n_glycosylation_sequon" }, { "start_pos": 286, "end_pos": 288, "annotation": "n_glycosylation_sequon" }, { "start_pos": 361, "end_pos": 363, "annotation": "n_glycosylation_sequon" }, { "start_pos": 450, "end_pos": 452, "annotation": "n_glycosylation_sequon" }, { "start_pos": 459, "end_pos": 461, "annotation": "n_glycosylation_sequon" }, { "start_pos": 561, "end_pos": 563, "annotation": "n_glycosylation_sequon" }, { "start_pos": 590, "end_pos": 592, "annotation": "n_glycosylation_sequon" }, { "start_pos": 631, "end_pos": 633, "annotation": "n_glycosylation_sequon" }, { "start_pos": 672, "end_pos": 674, "annotation": "n_glycosylation_sequon" }, { "start_pos": 722, "end_pos": 724, "annotation": "n_glycosylation_sequon" }, { "start_pos": 723, "end_pos": 725, "annotation": "n_glycosylation_sequon" }, { "start_pos": 799, "end_pos": 801, "annotation": "n_glycosylation_sequon" }, { "start_pos": 810, "end_pos": 812, "annotation": "n_glycosylation_sequon" }, { "start_pos": 90, "end_pos": 92, "annotation": "n_glycosylation_sequon" }, { "start_pos": 984, "end_pos": 986, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YIE7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIE7" }, { "id": "PS50915", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50915" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Beta/gamma crystallin 'Greek key'", "eco_id": "ECO_0000259", "start_pos": 1126, "end_pos": 1170, "start_aa": "Gly", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1049, "end_pos": 1051 }, { "start_pos": 164, "end_pos": 166 }, { "start_pos": 165, "end_pos": 167 }, { "start_pos": 177, "end_pos": 179 }, { "start_pos": 286, "end_pos": 288 }, { "start_pos": 361, "end_pos": 363 }, { "start_pos": 450, "end_pos": 452 }, { "start_pos": 459, "end_pos": 461 }, { "start_pos": 561, "end_pos": 563 }, { "start_pos": 590, "end_pos": 592 }, { "start_pos": 631, "end_pos": 633 }, { "start_pos": 672, "end_pos": 674 }, { "start_pos": 722, "end_pos": 724 }, { "start_pos": 723, "end_pos": 725 }, { "start_pos": 799, "end_pos": 801 }, { "start_pos": 810, "end_pos": 812 }, { "start_pos": 90, "end_pos": 92 }, { "start_pos": 984, "end_pos": 986 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YIC2-1", "uniprot_ac": "A0A8V0YIC2", "uniprot_id": "A0A8V0YIC2_CHICK", "mass": { "chemical_mass": 45943.0, "monoisotopic_mass": 45943.0 }, "refseq": { "ac": "NP_001384139", "name": "protein PRRC1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384139" }, "gene_names": [ { "name": "PRRC1", "type": "recommended", "evidence": [ { "id": "A0A8V0YIC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIC2" } ] }, { "name": "PRRC1", "type": "synonym", "evidence": [ { "id": "NP_001384139", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384139" } ] } ], "protein_names": [ { "name": "Proline rich coiled-coil 1", "type": "synonym", "evidence": [ { "id": "A0A8V0YIC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIC2/entry#names_and_taxonomy" } ] }, { "name": "proline-rich and coiled-coil-containing protein 1", "type": "synonym", "evidence": [ { "id": "NP_001384139", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384139" } ] }, { "name": "protein PRRC1", "type": "synonym", "evidence": [ { "id": "NP_001384139", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384139" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: SRR13267649.186272.1, SRR13267659.221232.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000095.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001384139", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384139" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIC2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIC2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PRRC1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIC2", "locus": { "chromosome": "Z", "start_pos": 57292122, "end_pos": 57265430, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012640", "url": "https://www.ensembl.org/id/ENSGALG00010012640" } ] } } ], "crossref": [ { "id": "A0A8V0YIC2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YIC2", "database": "AlphaFoldDB", "categories": [] }, { "id": "427127", "url": "https://www.ncbi.nlm.nih.gov/gene/427127", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR026533", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026533", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR026534", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026534", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029001", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029001", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ELFPDQW", "url": "https://omabrowser.org/oma/group/ELFPDQW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YIC2", "url": "https://www.orthodb.org/?gene=A0A8V0YIC2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YN57", "url": "https://www.orthodb.org/?gene=A0A8V0YN57", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23276", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23276", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23276:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23276:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01931", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01931", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001384139", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384139", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YIC2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIC2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YIC2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIC2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YN57", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN57", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YN57-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN57-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MMEESGIEATPPGTPPPSTAGSTAASATPVSLALSSPLATPSMSSPAYSPPLPAAVAPLPPPVMTSATPSFVPSAAVSTIAPPLAPAPAPVTSSAFSTSLPQFSAPPPLSSTTGSGLSVPPTGPPISGFSLSSTYDITRGHAGRAPQSPLMPSYSAPPVTGVLADPITQQAPFSSPLASGTGSGSSITFPEEHEDPRVSAAQSGAPTGGLWGFIKGVAENPMVKSVLDKTKHSVESMITTLDPGMVPYIKTGGELDIVVTSNKEVKVAAIRDAFQEVFGMAVVTGEAAQSNIAPQPVGYAAGLKGAQERIDSLRRTGVIHEKQPAVSVESFIEELLPDKWFDIGCLIIEDPVHGIHLEAFTQATPVPLQYVQQAKSLTPQDYNLRWSGLLVTVGEVIEKNLLNISRTDWHAVFTGMSRRQMIYSTAKALAGMYKQHLPPRTV", "length": 442, "header": "tr|A0A8V0YIC2-1|A0A8V0YIC2_CHICK Isoform 1 of Proline rich coiled-coil 1 OS=Gallus gallus OX=9031 GN=PRRC1 PE=3 SV=1 CANONICAL=A0A8V0YIC2-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YIC2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIC2/entry#A0A8V0YIC2-1", "sequence": { "sequence": "MMEESGIEATPPGTPPPSTAGSTAASATPVSLALSSPLATPSMSSPAYSPPLPAAVAPLPPPVMTSATPSFVPSAAVSTIAPPLAPAPAPVTSSAFSTSLPQFSAPPPLSSTTGSGLSVPPTGPPISGFSLSSTYDITRGHAGRAPQSPLMPSYSAPPVTGVLADPITQQAPFSSPLASGTGSGSSITFPEEHEDPRVSAAQSGAPTGGLWGFIKGVAENPMVKSVLDKTKHSVESMITTLDPGMVPYIKTGGELDIVVTSNKEVKVAAIRDAFQEVFGMAVVTGEAAQSNIAPQPVGYAAGLKGAQERIDSLRRTGVIHEKQPAVSVESFIEELLPDKWFDIGCLIIEDPVHGIHLEAFTQATPVPLQYVQQAKSLTPQDYNLRWSGLLVTVGEVIEKNLLNISRTDWHAVFTGMSRRQMIYSTAKALAGMYKQHLPPRTV", "length": 442, "header": "tr|A0A8V0YIC2-1|A0A8V0YIC2_CHICK Isoform 1 of Proline rich coiled-coil 1 OS=Gallus gallus OX=9031 GN=PRRC1 PE=3 SV=1 CANONICAL=A0A8V0YIC2-1" }, "locus": { "chromosome": "Z", "start_pos": 57290929, "end_pos": 57272428, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030250.1", "url": "https://www.ensembl.org/id/ENSGALT00010030250.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017551.1", "url": "https://www.ensembl.org/id/ENSGALP00010017551.1" } ] } }, { "isoform_ac": "A0A8V0YN57-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIC2/entry#A0A8V0YN57-1", "sequence": { "sequence": "MMEESGIEATPPGTPPPSTAGSTAASATPVSLALSSPLATPSMSSPAYSPPLPAAVAPLPPPVMTSAFSTSLPQFSAPPPLSSTTGSGLSVPPTGPPISGFSLSSTYDITRGHAGRAPQSPLMPSYSAPPVTGVLADPITQQAPFSSPLASGTGSGSSITFPEEHEDPRVSAAQSGAPTGGLWGFIKGVAENPMVKSVLDKTKHSVESMITTLDPGMVPYIKTGGELDIVVTSNKEVKVAAIRDAFQEVFGMAVVTGEAAQSNIAPQPVGYAAGLKGAQERIDSLRRTGVIHEKQPAVSVESFIEELLPDKWFDIGCLIIEDPVHGIHLEAFTQATPVPLQYVQQAKSLTPQDYNLRWSGLLVTVGEVIEKNLLNISRTDWHAVFTGMSRRQMIYSTAKALAGMYKQHLPPRTV", "length": 414, "header": "tr|A0A8V0YN57-1|A0A8V0YN57_CHICK Computationally mapped isoform of Proline rich coiled-coil 1 OS=Gallus gallus OX=9031 GN=PRRC1 PE=3 SV=1 CANONICAL=A0A8V0YIC2-1" }, "locus": { "chromosome": "Z", "start_pos": 57290929, "end_pos": 57272428, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030258.1", "url": "https://www.ensembl.org/id/ENSGALT00010030258.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017554.1", "url": "https://www.ensembl.org/id/ENSGALP00010017554.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 122, "start_aa": "Thr", "end_pos": 122, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr122", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 40, "start_aa": "Thr", "end_pos": 40, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr40", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "F1RKK5-1", "protein_name": "Protein PRRC1", "gene_name": "PRRC1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MMEESGIETTPPGTPPPSSTGLVAAAAPSPSPSPLAATSSFSSPNVSSVQPLPPHAFSTPQPSLPSVRPAVPLPPFVPPSPVPSVPPLGTSVPPPVSPPTAAAFSSPPLSHFPPSTSAPNAPSPAPSAGPPTSGFSVGSAYDITRGHAGRAPQTPLMPSFSAPPVTGILPAPITQQAGLTSLAQGAGTTSAITFPEEQEDPRIGRGQDEASAGGLWGFIKGVAGNPMVKSVLDKTKHSVESMITTLDPGMAPYIKSGGELDIVVTSNKEVKVAAIRDAFQEVFGLAVVIGEAGQSNIAPQPVGYAAGLKGAQERIDSLRRTGVIHDKQTAVSVENFIAELLPDKWFDIGCLIVEDPVHGIHLEAFTQATPVPLEFVQQAQSLTPQDYSLRWSGLLVTVGEVLEKSLLNVSRTDWHVTFTGMSRRQMIYSAAKAIAGMYKQRLPPRAM", "length": 447 }, "evidence": [ { "id": "A0A8V0YIC2", "url": "https://omabrowser.org/oma/group/A0A8V0YIC2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q3T1I4-1", "protein_name": "Protein PRRC1", "gene_name": "Prrc1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MMEESGIETTPPGTPPPHSAGLAAVPSTEAHLAVTSSFSSPNTSGMETVPPHSHSTPQPSLPPVQPSAPPPFVPLSPAPSTPLSGTSVPPSVSPSPATAFSGPPLSHFPPATSASGALLSAPPSGPPISGFSVGTTYDITRGHAGRAPQTPLMPSFSAPPVTGILPAPITQQASMTSLAQGPGTTSAITFPEEQEDPRISRGQDDAPAGGIWGFIKGVAGNPMVKSVLDKTKHSVESMITTLDPGMAPYIKSGGELDIVVTSNKEVKVAAVRDAFQEVFGLAVVVGEAGQSNIAPQPVGYAAGLKGAQERIDSLRRSGTIHEKQTAVSVENFIAELLPDKWFDIGCLVVEDPVHGIRLEAFTQATPVPLEFVQQAQSLTPQDYNLRWSGLLVTVGEVLEKSLLNVTRTDWHLAFTGMSRRQMIYSAAKALAGMYKQRLPPRPL", "length": 443 }, "evidence": [ { "id": "A0A8V0YIC2", "url": "https://omabrowser.org/oma/group/A0A8V0YIC2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q3UPH1-1", "protein_name": "Protein PRRC1", "gene_name": "Prrc1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MMEESGIETTPPGTPPLHPAGLAAVPSTEAHSAATSSFSSPNVSGMESLPPHVYSTPQPSLPPVQPSAPPPFVSMSPAPSVPLSGTSVPPSVSPSPATAFSGPPMSHFPPATSASGALLSAPPSGPPISGFSVGTTYDITRGHAGRAPQTPLMPSFSAPPVTGILPAPITQQASMTSLAQGPGTTSAITFPEEQEDPRINRGQDDAPAGGIWGFIKGVAGNPMVKSVLDKTKHSVESMITTLDPGMAPYIKSGGELDIVVTSNKEVKVAAVRDAFQEVFGLAVVVGEAGQSNIAPQPVGYAAGLKGAQERIDSLRRSGAIHEKQTAVSVENFIAELLPDKWFDIGCLVVEDPVHGIRLEAFTQATPVPLEFVQQAQSLTPQDYNLRWSGLLVTVGEVLEKSLLNVSRTDWHLAFTGMSRRQMIYSAAKAVAGMYKQRLPPRPM", "length": 443 }, "evidence": [ { "id": "A0A8V0YIC2", "url": "https://omabrowser.org/oma/group/A0A8V0YIC2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q5XJA3-1", "protein_name": "Protein PRRC1", "gene_name": "prrc1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MMEESGIESTPPATPPPPSTVVASPPPLTSGATRPQTVPSPSGISAFTPGDFSSPVPSVALTSTLPPMQSSVPPLPLSSISSPLGLSGPYGIPSASFASPAAGPPLSTGPPLGPVLSAPPMGPPTTGFSVSGGYDITRGHAGRTPQTPLMPSFSSASPMPGIVTNPMMQQPVSGGLDVSSPITFPEDVEDPRVTPDSNAPGGLWGFIKGVAGNPMVKTVLDKTKHSVESMITTLDPGMAPYIKSGGDVDIVVTSDKEVKVAAVRDAFQEVFGLAMVTGEAGQSNIAPQPVGYAAGVKGAQERIDSLRRAAVIHEKQPVVSVENFIAELFPDKWFDIGCLILDDPGYGIHIETFTQATPVALEHVQQAQSLTPPDYNLRWSGLLVTVGEVLERNVPNVSRTDWHQAFTGMSRRQMIYSAAKALAGMYKLRLPSRTV", "length": 435 }, "evidence": [ { "id": "A0A8V0YIC2", "url": "https://omabrowser.org/oma/group/A0A8V0YIC2/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q96M27-1", "protein_name": "Protein PRRC1", "gene_name": "PRRC1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MMEESGIETTPPGTPPPNPAGLAATAMSSTPVPLAATSSFSSPNVSSMESFPPLAYSTPQPPLPPVRPSAPLPFVPPPAVPSVPPLVTSMPPPVSPSTAAAFGNPPVSHFPPSTSAPNTLLPAPPSGPPISGFSVGSTYDITRGHAGRAPQTPLMPSFSAPSGTGLLPTPITQQASLTSLAQGTGTTSAITFPEEQEDPRITRGQDEASAGGIWGFIKGVAGNPMVKSVLDKTKHSVESMITTLDPGMAPYIKSGGELDIVVTSNKEVKVAAVRDAFQEVFGLAVVVGEAGQSNIAPQPVGYAAGLKGAQERIDSLRRTGVIHEKQTAVSVENFIAELLPDKWFDIGCLVVEDPVHGIHLETFTQATPVPLEFVQQAQSLTPQDYNLRWSGLLVTVGEVLEKSLLNVSRTDWHMAFTGMSRRQMIYSAARAIAGMYKQRLPPRTV", "length": 445 }, "evidence": [ { "id": "A0A8V0YIC2", "url": "https://omabrowser.org/oma/group/A0A8V0YIC2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIC2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIC2" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIC2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIC2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIC2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIC2" } ], "pmid": "" }, { "name": "protein kinase A regulatory subunit binding", "id": "GO:0034237", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034237", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIC2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIC2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "epithelial structure maintenance", "id": "GO:0010669", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010669", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIC2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIC2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 403, "end_pos": 405, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YIC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIC2" }, { "id": "PF01931", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01931" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Non-canonical purine NTP phosphatase/PRRC1", "eco_id": "ECO_0000259", "start_pos": 257, "end_pos": 373, "start_aa": "Ile", "end_aa": "Gln", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 40, 122 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 403, "end_pos": 405 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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"https://www.uniprot.org/uniprotkb/A0A8V0YIC5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIC5", "locus": {} } ], "crossref": [ { "id": "A0A8V0YIC5", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YIC5", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR039500", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039500", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052461", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052461", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR48422", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48422", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR48422:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48422:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF14851", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14851", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YIC5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIC5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YIC5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIC5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLNRPFSLLSLQPKCGGSAAVPVSTVWAVGLRADGAPPGLPKPEDAPHALSPGALSAAMESRKQNMELLSNSMAAYAHIRANPESFGLYFVLGVCFGLVLTLCLLLLRISCRPRAQRTARPGPADLSEDDDDDDDEDEEEDTVDRAASESLLPMTEIPSECHGPGDGAPPVNVFASAEELERAQRLEERERIIREIWRNGQPDLLGADAPRRGHFY", "length": 216, "header": "tr|A0A8V0YIC5-1|A0A8V0YIC5_CHICK Isoform 1 of Eva-1 homolog B OS=Gallus gallus OX=9031 GN= PE=3 SV=1 CANONICAL=A0A8V0YIC5-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YIC5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIC5/entry#A0A8V0YIC5-1", "sequence": { "sequence": "MLNRPFSLLSLQPKCGGSAAVPVSTVWAVGLRADGAPPGLPKPEDAPHALSPGALSAAMESRKQNMELLSNSMAAYAHIRANPESFGLYFVLGVCFGLVLTLCLLLLRISCRPRAQRTARPGPADLSEDDDDDDDEDEEEDTVDRAASESLLPMTEIPSECHGPGDGAPPVNVFASAEELERAQRLEERERIIREIWRNGQPDLLGADAPRRGHFY", "length": 216, "header": "tr|A0A8V0YIC5-1|A0A8V0YIC5_CHICK Isoform 1 of Eva-1 homolog B OS=Gallus gallus OX=9031 GN= PE=3 SV=1 CANONICAL=A0A8V0YIC5-1" }, "locus": { "chromosome": "23", "start_pos": 4418081, "end_pos": 4416121, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010035540.1", "url": "https://www.ensembl.org/id/ENSGALT00010035540.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020650.1", "url": "https://www.ensembl.org/id/ENSGALP00010020650.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIC5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIC5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YIC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIC5" }, { "id": "PF14851", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14851" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "EVA1", "eco_id": "ECO_0000259", "start_pos": 65, "end_pos": 206, "start_aa": "Asn", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YIE9-1", "uniprot_ac": "A0A8V0YIE9", "uniprot_id": "A0A8V0YIE9_CHICK", "mass": { "chemical_mass": 234784.0, "monoisotopic_mass": 234784.0 }, "refseq": { "ac": "XP_015132999", "name": "sperm flagellar protein 2 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015132999" }, "gene_names": [ { "name": "SPEF2", "type": "recommended", "evidence": [ { "id": "A0A8V0YIE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIE9" } ] }, { "name": "SPEF2", "type": "synonym", "evidence": [ { "id": "XP_015132999", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015132999" } ] } ], "protein_names": [ { "name": "Sperm flagellar 2", "type": "synonym", "evidence": [ { "id": "A0A8V0YIE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIE9/entry#names_and_taxonomy" } ] }, { "name": "sperm flagellar protein 2 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015132999", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015132999" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052572.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015132999.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015132999", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015132999" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIE9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIE9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SPEF2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIE9", "locus": { "chromosome": "Z", "start_pos": 11397639, "end_pos": 11350311, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010014805", "url": "https://www.ensembl.org/id/ENSGALG00010014805" } ] } } ], "crossref": [ { "id": "427435", "url": "https://www.ncbi.nlm.nih.gov/gene/427435", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001715", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001715", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006580", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006580", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR010441", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010441", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012337", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012337", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR025398", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025398", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036872", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036872", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052634", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052634", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR054517", "url": "https://www.ebi.ac.uk/interpro/entry/IPR054517", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057456", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057456", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:427435", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427435", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "IMETKQQ", "url": "https://omabrowser.org/oma/group/IMETKQQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YIE9", "url": "https://www.orthodb.org/?gene=A0A8V0YIE9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14919", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14919", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14919:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14919:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF06294", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06294", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14291", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14291", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF22946", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22946", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25431", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25431", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015132999", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015132999", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YIE9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIE9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YIE9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIE9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSEILCEWLNEEVKLSRSVVPGSLSEEFSTGYLFGELLHKYGLQDDFNQFSQSRAANAKLNNFSLLEPTLQLLGVQFNENVAHDIMIGKRGAATKLLYELYIALEKKRKTKLTGVAMEAMRPAAPARFKSIGSVSFRERLKSLTSRQADLELWQVSDHFEMKSKAIEDKIARIHISEQQKSLKPQEEQRAQDSEKHRIGRRQNEIMARIQAAVIQVPKPSLSHTLKSNEAKKILKKKREAEDTYKEINKFEKSLVGNAFEVHSQVTDSEIQESLQTQKLQETTLETTAQAATELLPTYSDDDYVRKIQKYLEEDMFAREQREKRRRKMLMEQLIAHEAEEEIYQEEQLVYRLMRQSQQERRIAVQLMHVRHEKEVLKQNRIFREKQYEERRLKEFQEALDREAALAKQEKIDYEEQSVKERERHEKIAIERAQARYKKHYSACWEVIDQIVDLSTKIGEYRVLTNNKVPLKLICDWKELFFNGNSIYEKASIKTLPSEPSPEQLLELNKMDLLDEKDYDEYKNMTGEWCPTEENRENKSLNNNILGHVLHRLMEIFYPSKPRCTLPVLPSFPIKGCILGKVFSGKTTCVKFLEKVCDIQVLSVDTLVQEAIQAFLNNEMKTEHSLISQEAESSAKQYKVQRNFSETSMKYLTDTFTNGTKGNHPFKKHPSDQATVSDHKENDISKLSVRAQLGAASQKLLKKGKSIPDELLVDILLEAIKQTPPEKGWILDGFPTTINQARLFEKACTGIDPDETEAKYVNCGKLSLVTNPRTPNKPPVTLPAFDVSILLDISDTTVLKRVASLMSDKSKPSEIEQEDSSQNSDVKIVEEKTDLARDQVLHRLSGFLDTWPKLENWFSDHQNTLVKVNAEMEESTVCKTVKEILIEEIYKKQNRRYVQEKSPEEKALPVTPQDLLSPVSVTPLIKPGTDEWIYVDEPLPKEIPDFLVPYWEMVENVYVNTIKTVLRCLRDEQYSVIYYLADIRKNFQDYLKHPDHKQEFVSQWQSDFNSIPDDLREDEETKAELHQRVTDLRDLLWDICDKRREEAEQERTDIMNDGWLRDHKGIAINHFFSLMQVEVDRFQDTKRLLHDYYRAMEGKIPTEDRQSFTRLPLLDIIDKEQQEDQNESRRIPLVSYKLPSPETNITKSKSKGNLLKSVKDENSSENVVVALGKDENVIRDTWQTAVTAVSDMVRAEIQSKEVKEEGEKQTEVKEDTKSSQTISSKSTGKDAKDTKKSPKSPTKTKGPRSTASAAEDSPVPLTAEELKKQKLILKIQQEYFAALKHEEKATKTRLKLIKAKALAYVEELTMKAEEAYKDMEKWLGERFLAEMSSVEKLIEVGRHHIESSSKIQYEMNLEETDFFISSDVKVIPDPVPPPQVPLIETSESSTLTISQLNTFHKHFLQVAPKAIRALKQFKGRSNSSSKREVDDRGKEKKDLEHPRIRKNRRFPKIWLTKYSWLKYDDERGIMFCALCRKHNVDLGESIHNFCSGTDDFKLEFINTHQNSEAHAWATCMEAASTASPNTVSAEQTLKSMNSITIGRVESTFRTCHAIAKSVQPFTDLDWIYKSDDVKGTDIGSLFRNYKSARMFKHFMAEAERRALKEELENCKFFSLISDEFTDSISKSAAVVYVHFANEGKVHCQIVGVQSVQKNDASTIKSAIEETFQINLQLSLASLDWSRKLVGFGSEETDVMTGQNNGVANLMREIQPCVQSVHCFAHRLRLAYKGALENIQLYSLTNGLRSMYYFYHSSTLNKKNLKAIYEAIKLHPAIPSCTGGSQWFSRLQTALQILLKGHPAFVLHLDKTKGDSRSSNRQKVKGLLYLLLKMEIVKFSHFLLDVINVLNILLHITMDHNSSIADIFATMQSTVETLQMYQARAGPMERLMKAIQHFHGHQLVGNGNISAVRTKVPSNVVKRLSDCFCDANQGVLKATLIGSFNLWPDKMKQVIVFGEKEVSVLSKHYEAILEAASVKISEVEIEWSMLKLELYNRFQNIQTLTWDSVNAHYSKKYPSILALVDLILTLPASSAEIDQGSGKESHHDASAL", "length": 2046, "header": "tr|A0A8V0YIE9-1|A0A8V0YIE9_CHICK Isoform 1 of Sperm flagellar 2 OS=Gallus gallus OX=9031 GN=SPEF2 PE=1 SV=1 CANONICAL=A0A8V0YIE9-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YIE9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIE9/entry#A0A8V0YIE9-1", "sequence": { "sequence": "MSEILCEWLNEEVKLSRSVVPGSLSEEFSTGYLFGELLHKYGLQDDFNQFSQSRAANAKLNNFSLLEPTLQLLGVQFNENVAHDIMIGKRGAATKLLYELYIALEKKRKTKLTGVAMEAMRPAAPARFKSIGSVSFRERLKSLTSRQADLELWQVSDHFEMKSKAIEDKIARIHISEQQKSLKPQEEQRAQDSEKHRIGRRQNEIMARIQAAVIQVPKPSLSHTLKSNEAKKILKKKREAEDTYKEINKFEKSLVGNAFEVHSQVTDSEIQESLQTQKLQETTLETTAQAATELLPTYSDDDYVRKIQKYLEEDMFAREQREKRRRKMLMEQLIAHEAEEEIYQEEQLVYRLMRQSQQERRIAVQLMHVRHEKEVLKQNRIFREKQYEERRLKEFQEALDREAALAKQEKIDYEEQSVKERERHEKIAIERAQARYKKHYSACWEVIDQIVDLSTKIGEYRVLTNNKVPLKLICDWKELFFNGNSIYEKASIKTLPSEPSPEQLLELNKMDLLDEKDYDEYKNMTGEWCPTEENRENKSLNNNILGHVLHRLMEIFYPSKPRCTLPVLPSFPIKGCILGKVFSGKTTCVKFLEKVCDIQVLSVDTLVQEAIQAFLNNEMKTEHSLISQEAESSAKQYKVQRNFSETSMKYLTDTFTNGTKGNHPFKKHPSDQATVSDHKENDISKLSVRAQLGAASQKLLKKGKSIPDELLVDILLEAIKQTPPEKGWILDGFPTTINQARLFEKACTGIDPDETEAKYVNCGKLSLVTNPRTPNKPPVTLPAFDVSILLDISDTTVLKRVASLMSDKSKPSEIEQEDSSQNSDVKIVEEKTDLARDQVLHRLSGFLDTWPKLENWFSDHQNTLVKVNAEMEESTVCKTVKEILIEEIYKKQNRRYVQEKSPEEKALPVTPQDLLSPVSVTPLIKPGTDEWIYVDEPLPKEIPDFLVPYWEMVENVYVNTIKTVLRCLRDEQYSVIYYLADIRKNFQDYLKHPDHKQEFVSQWQSDFNSIPDDLREDEETKAELHQRVTDLRDLLWDICDKRREEAEQERTDIMNDGWLRDHKGIAINHFFSLMQVEVDRFQDTKRLLHDYYRAMEGKIPTEDRQSFTRLPLLDIIDKEQQEDQNESRRIPLVSYKLPSPETNITKSKSKGNLLKSVKDENSSENVVVALGKDENVIRDTWQTAVTAVSDMVRAEIQSKEVKEEGEKQTEVKEDTKSSQTISSKSTGKDAKDTKKSPKSPTKTKGPRSTASAAEDSPVPLTAEELKKQKLILKIQQEYFAALKHEEKATKTRLKLIKAKALAYVEELTMKAEEAYKDMEKWLGERFLAEMSSVEKLIEVGRHHIESSSKIQYEMNLEETDFFISSDVKVIPDPVPPPQVPLIETSESSTLTISQLNTFHKHFLQVAPKAIRALKQFKGRSNSSSKREVDDRGKEKKDLEHPRIRKNRRFPKIWLTKYSWLKYDDERGIMFCALCRKHNVDLGESIHNFCSGTDDFKLEFINTHQNSEAHAWATCMEAASTASPNTVSAEQTLKSMNSITIGRVESTFRTCHAIAKSVQPFTDLDWIYKSDDVKGTDIGSLFRNYKSARMFKHFMAEAERRALKEELENCKFFSLISDEFTDSISKSAAVVYVHFANEGKVHCQIVGVQSVQKNDASTIKSAIEETFQINLQLSLASLDWSRKLVGFGSEETDVMTGQNNGVANLMREIQPCVQSVHCFAHRLRLAYKGALENIQLYSLTNGLRSMYYFYHSSTLNKKNLKAIYEAIKLHPAIPSCTGGSQWFSRLQTALQILLKGHPAFVLHLDKTKGDSRSSNRQKVKGLLYLLLKMEIVKFSHFLLDVINVLNILLHITMDHNSSIADIFATMQSTVETLQMYQARAGPMERLMKAIQHFHGHQLVGNGNISAVRTKVPSNVVKRLSDCFCDANQGVLKATLIGSFNLWPDKMKQVIVFGEKEVSVLSKHYEAILEAASVKISEVEIEWSMLKLELYNRFQNIQTLTWDSVNAHYSKKYPSILALVDLILTLPASSAEIDQGSGKESHHDASAL", "length": 2046, "header": "tr|A0A8V0YIE9-1|A0A8V0YIE9_CHICK Isoform 1 of Sperm flagellar 2 OS=Gallus gallus OX=9031 GN=SPEF2 PE=1 SV=1 CANONICAL=A0A8V0YIE9-1" }, "locus": { "chromosome": "Z", "start_pos": 11396635, "end_pos": 11350425, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010035626.1", "url": "https://www.ensembl.org/id/ENSGALT00010035626.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020685.1", "url": "https://www.ensembl.org/id/ENSGALP00010020685.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:427435", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427435", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A5G2QPV2-1", "protein_name": "Sperm flagellar 2", "gene_name": "SPEF2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSEILCHWLNQELKVSQTVSPKSFAKAFSSGYLIGEVLHKYELQDDFAEFSEKRISSAKLNNFSRLEPTLHLLGVQFDQNVAHDIITEKPGVAMKLLYQLYIALQRKKKSGLTGVELQTMQPLTNTKLQNMKSEAFRDRLRNLIPRQTDVSLMRVSHRFQEKYKYKDEDLVHTHLKKLENFQKLQEEQRSFNIEKQRLSRRRQNEIMAQIQAAIIQIPKPASNRTLKALDAQKMMKKKKEAEDVANEIKKFEALIKKDLQAKESASKTSLDAAGQTTTDLLNTYSDDEYIKKIQKRLEEDAFAREQREKRRRRLLMDQLIAHEAQEEAYREEQLVSRLMRQSQQERRIAVQLMHVRHEKEVLWQNRIFREKQYEERRLKDFQDALDREAALAKQAKIDYEEQALREKEMHEQIAAERVQARYKKHYSICAEILDQILDLSTKVADYRMLTNNLIPYKLMHDWKELFFNGMPIYEQASLKHLSAKPSTEQLIELEKRDLLDNNDYEEYKNMVGEWALPEEMVDNIPPSDNRILGHVIHRLIEHSLPPQVESTAPELPSFAIKGCLLGKTFSGKTTALKFLQKYFPIEVLSIDTLVQEAIQAFHNNEKVSGALQLQKAAEEKASPVRQESGDRSQNLHNVLSAEGTPETEDETRLSTKKTPKAEEVIASASLSELTTRAQLGAKSEKLLKKGKSISDTLLVSIVVNAINQIPIYKGWILDGFPMTLNQAKLLEEALTGFNRNLIELEGKKSQISTLAVDPTASREVPLPPSAFDFVMLLDISDNTSLNRMNDIMAEAFLSETPHENINQRVAAENQDMDEDQNLRDQIQHRIIGFWDHWPSLEQWFTEPENILIKMNAEVDEQSLCQKVKEMFMAEIMKKENKAKKKSEEKEAEKKEEFSLPEATPPTPPAPPPSEPEKEKEAHPPHERSKTPTAKGKPASEPPHGNRESPQEGKGKKSETSPKRKGSPRGKSPGGKAPVKKSPADSTDVSPVPAVPPPSKPGSEEWVFVNEPIPEEIPLFLVPYWKLIENSYINSIKTVLRHLREGQHTVLAYLYDTRTGFQQFLRRPDHKQNFVSQWQADFNSLPDDLWEDEETKAELHQRVNDLRDRLWDICDARKEEAEQERLDIINESWLQDSTGIAMNHFFSLMQAELNRFQDTKRLLQDYYRGMECKIPTDDTKRLTRVPLVQLDNKDTLEFQLRIPLVPRRSISPESALSKPKIKALLKGNIDYSLENVELNFEADEKVVMDTWQQASLAVSHMVAAEIHQRLMEEEKENQPADTKEKPPQTAANKKVKKEPPKKKREDKKGKGKSPPMAESAPVITVEEIAEMERKNELRLRIKEEHLAALQFEERATQFRLELIKTKALAFLEDLVTKADVYKLMEKWLGERYLNEMASVEKLTEVARYHIETSTKIQNELYLDQEDFFINGNIKVFPDPPPPVRPPPVEKEENGTLTIEQLDNLRDQFLDIAPKDRDPPDGGRRVTKKQKRPRTLDHYLPKRNNQFLKIWLKKYPWLVYDEILNIMFCGLCRKHGVRSKGNQVSFFYGTDNFRAEFLNAHHLSEAHAKASLTEATSGSPGSRAPTELMVRAMSKVTLGRVENLFRSCHAIAKTGRPLEDFIWMCTLDDMKGVDLGPVFRTNTSARTFTYFIAEVERRTLREKLQTSKFFSIIRDGMTDSSVEEAELVYVQFARAGQVHCQIVGVQTVEEKDPPGIKKAIEKTLERNLQLRLANQDWAKKLVGFGSDGAPGPEGEKSRRVALLLRDLQPRVLAVYCFAHHLELSYKAVFQSVPLYNDVTRLLHSLHRFHHNSPVPTSSLITAFKSLPLRPGTPSPVDGRRWLRGLQAALQNFLKGYPAIVQHLLSTDEGGSDTSHQKAKELLDVLLQADIVKFVHFLVDVINVLSLLSHVIQNRNSSIADIFATLESTLEMLRIYQTRPGPKERRVESVTHFHGNCLGGRGNISDVRNMVLTHLIERLQGCFRDASQDVVKATTIGSFKLWPAKIKQEFGEKEVSILTAHYEPILEAAQVKIDEVDTEWSMLKLEIYARFQNIRKLTWDFVNSVYLHKYPNILTLVDLVLSLPASSAEAERGFSQMERTNSQVHAKVKADDMTDLLIIQLNSPDIKNFDPRKAIHLWNTRTPSSPGDTRPNSDCSSRSESPDESDY", "length": 2164 }, "evidence": [ { "id": "A0A8V0YIE9", "url": "https://omabrowser.org/oma/group/A0A8V0YIE9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0AC58JJ34-1", "protein_name": "Sperm flagellar protein 2 isoform X1", "gene_name": "spef2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSDIICQWLNSELRLSKVVEPHSFARDFSNGYLIGEILYRYELQDDFHLFSKQNTSNAKLNNFTRIEPTLQLLTVPFDLTMAKAVMLGRHGAATRLLYQLYILLQRKKRAGLTATAMEVMQPAATARLHRIENSIYTERLKTVVKREADLKMQKIAKRFHKRGQEMFSRSVMTELLKEEDRLKRQEERRLRDIEKHRQARRKQNEIMIQIQSAVVQIPKPPHIRTSRASEKQQQFRKKQEAQHVHREIAQFEKKKKTTSPPEGGALLFSGRVTQPMSTGDKAQWNKDYIENIRQRLEEDATAREQREMRRRRALMEQLQAHEAQQEALREEQMVSRLMRQTQQEKRITVQLMQIKQQKEVLRENRIFQERQYQERRQRDFQEALDREAVLAQQERLERSEQLRIEHELHKQLAEERAQARYQKHFGICRDILGQIVDLATKAGEYRLLTANLIPVKLMQEWMELFYSGKPLYEVACVDPKPTEPSPEQIIELEKLQILNNQDYDEYVAMIGEWALDAETERQTNAGNSDILDHVLNRLRNMIVPPTVSTPPPLFPRFTIRACMLGKTFSGKTTCLSRISSTLNIHVLSANTLIQDALSAYQQEKQAASESQNEKSLEKNVSQTEHTTEQLQKDEQETSSPLESGPQPHEASSGLHEKEDKEESKAIPKWSSRAQHGAAVEKVLRTGQAVPDQLLVDIIVDAIRNIPADSGWILDGFPVDISQAQMLEKALNMTELDGTKTQNNLSTTKNGPKDAAPPSPALDLVVLLDVSDEQVLERATTQPPEGTQIVNGESIKQEKGSSDAAEENTSMPDLNTQDPESLSDDKSLGRTQIQFRISGFHQTWPKLEKWFGDQQNILVKVTAGVDKDTLFSNVETILRDSIESVEKGAALADTRRASVTSTPEQTRPESACSSKSSRATPKSARRSFAEEPLPKELAEYLVPYWENVCSSYVTNVKTVMQNLRGERELIIHHLYNIRENFRQYLQKPDLKQEFVSSWQRDYNSVPDNIREDEETKGELHQRLDDLRERLWDISDKRKEEAEQEKAGVIHDGWLEDHTAVLINNYSALMQIEVGRFQDCVCLLKDHYSTMGKTAFESKCDFARVPLLDITADQHVDESKISESAPSEKSVKNAEEKDSEIVDRMKTKVFPLVSCRSPTSEILKQPLHQADENLLQEFFQAAIAIFRSMVSAEMRQWDEEEVDEDQKQMEAQKAQTLTSATDVRKAGKQKGAPPPPPPPEPSPQPAARNPEELRKRAEKKRFKQELSAALKPEENAVKQRLELVKAHGLRTVISLQHKAEQVYRNMEEWMKARYLAEMKSIDQLTDLVRQHIETGVQIRHELVLQSTDFCVDGDTRVLLSPELAPRRSLLEQPKNSTLTVQQLHVLCTQLRKIAPTGLMCRSELTEALHELTSAHMGTDVLPEAWMHITPSQVEELVCILAQDSEMLDWRQFLLSAALPWPFPTQTQLIKTLQRYRDIDTTGNGLITQEQYEQVELWFPSEQDASVPDDPTEPVPYDRLANLKKFFFSLFASTHSSPLLLDYLMMLLYFCCHPEAAQGFTRALSLITGHTLHYKHTTPLTQSVPCLEGAGVVDDAGADNEEEQHRGVESEDVGVSVDDVLRVLSHGEDLVLHLNRFQPVHRSRDELREELLKVFKELGFSVEEKIPFSTLSQHPFLQDLMEGSSQYLLHDIHKVFQTRQTEDSRSFST", "length": 1706 }, "evidence": [ { "id": "A0A8V0YIE9", "url": "https://omabrowser.org/oma/group/A0A8V0YIE9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q8C9J3-1", "protein_name": "Sperm flagella and cilia-associated protein 2", "gene_name": "Spef2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSEILCQWLNQELRVSRTVSPKSFAKAFSNGYLIGEVLFKFELQSDFAEFSESRGSTAKLNNFSRLQPTLHLLGLQFDQNVAQSIITEKPGAATKLLYQLYIALQKKKKTGLTGLEIQTMQPQTNLRLQTLKSEAFREQRLNRRRQNEIMAKIQAAIIQIPKPESNRTLKAIEAQKLMKKKKEAEDVANEIKKFEALIKKDLQIKESVSKTSLETTDQTTAELLNTYSDDDYIKKIQKRLEEDAFAREQREKRRRRLLMDQLMAHEAQEEAYREEQLIHRLMRQSQQERRIAVQLMHVRHEKEVLWQNRIFREKQFEERRLKDFQDALDREAALAKQAKIDFAEQTLREKEIHEKISVERAQQRYKKHYGICAEILDQMLDLCTKVADYRLLTNNLIPHKMMHDWKELFFSGIPIYEQTSLTHGQTEPTEDHRAEVKKRNLLDSKDYEDYKNMVGEWALPEDMVNSSPPSNNSILGHVLLRLIEKADPSASNAEATELPSLAVKGCILGKTLSGKTTVLKSLQNDFPVHVLSIDTLVQEAIQAFHERQKSGKTPPTQEDDKRDPVVNQEKVSKTQDKNVLAVSPVPGDRTSQKEGVKINEFEQFRSSDSFLSLSMRAQLGAKSELMLRRGKSIPDILLVSILVNAIKEIPVDQSWVLDGFPITLNQAKLLEEALTGYKRKFLQLKKKKEQMPTLALDPSTSTEVSLLPSALDFVILLDISDNSSLARTNDIIAKEISHEISHENVGRPGTGTSQDNKSEDRNLRDHIQHRIVGFLDNWPLLEEWFTQPKNILTKVNAEIDEALLCQKVKEIFATETVNKKIKVEKTLEEKETEKKAGAPPAEPPAMSPPLSSEAEKDKELHQAKTPGKGKTQSVSPKGKAQGGKVSVKKSPVGSAEVSPTPTAPPPPKAGTEEWVYVNEPIPEELPSFLVPYWELIEKSYINHIKTVLRHLRERQHNVLSYLYETRTSFQEFLRRPDHKQDFVSQWQADFNSVPEDLWEDEETKAELHQRVNDLRDRLWDICEARKEEAEQERLDIINESWLQDSIGITMNHFFSLMQAEVNRFQDTKRLLQDYYRAMESKIPLEDSKKFTRVPLVQLDGKEISESQLRIPLVPRISNSPENSAVKPKVGTFLKGRSDPPLEVLEANFEIDEKILLDTWQQASLAISNMVAAEVHQRLTEEEKEPPQLDSKEKSPQSGANKKAKKEKEAPKKKKTDKKGKGKSSPVAEVSPVTVTPEEMAEMEKRNELRLRIKEEHLAALQTEEQAAQFRLELIKLKALSVLEDLVTKVIDVYRLMEKWLGKRYLNEMASIQKLTELARYHIETATKIQNEIYLSQEDFYINGDIKVFPDPSPPTRPPPVEREENGTLTIEQLDNLRDQFLDMAPKGIIGNKAFSDILLDLITLNLGTNNFPSSWMHLSQLDLQEITSLLTVNTEFVDWRKFLMVTAMPWPMALEDELLDTLQRFKALDEAQTGTITYEQYKQAGLWFSGDEDIKIPENPLEPLPFNRQEHLIEFFFRLFADCEKEPPQLDYTQMLLYFACHPDTLEGVYRALSVAVGTHIFRQVETPMLMAEKTSISTVSPIEEFPETEESSAKEDRELKEEKDDQKEEEIPENANTEKISMETLLKVFGGGNEVLDANRFASYLKSENIYAENFIKTFQDLGARNLEPIAVNILLKHPYIQDLIANYVDYKFPDIKMILQRSEHAQGSDGERSPSRLTDEKK", "length": 1724 }, "evidence": [ { "id": "A0A8V0YIE9", "url": "https://omabrowser.org/oma/group/A0A8V0YIE9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9C093-1", "protein_name": "Sperm flagella and cilia-associated protein 2", "gene_name": "SPEF2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSEILCQWLNKELKVSRTVSPKSFAKAFSSGYLLGEVLHKFELQDDFSEFLDSRVSSAKLNNFSRLEPTLNLLGVQFDQNVAHGIITEKPGVATKLLYQLYIALQKKKKSGLTGVEMQTMQRLTNLRLQNMKSDTFQERLRHMIPRQTDFNLMRITYRFQEKYKHVKEDLAHLHFEKLERFQKLKEEQRCFDIEKQYLNRRRQNEIMAKIQAAIIQIPKPASNRTLKALEAQKMMKKKKEAEDVADEIKKFEALIKKDLQAKESASKTSLDTAGQTTTDLLNTYSDDEYIKKIQKRLEEDAFAREQREKRRRKLLMDQLIAHEAQEEAYREEQLINRLMRQSQQERRIAVQLMHVRHEKEVLWQNRIFREKQHEERRLKDFQDALDREAALAKQAKIDFEEQFLKEKRFHDQIAVERAQARYEKHYSVCAEILDQIVDLSTKVADYRMLTNNLIPYKLMHDWKELFFNAKPIYEQASVKTLPANPSREQLTELEKRDLLDTNDYEEYKNMVGEWALPEEMVDNLPPSNNCILGHILHRLAEKSLPPRAESTTPELPSFAVKGCLLGKTLSGKTTILRSLQKDFPIQILSIDTLVQEAIQAFHDNEKVSEVLPIQKNDEEDALPVLQEEIKESQDPQHVFSAGPVSDEVLPETEGETMLSANADKTPKAEEVKSSDSFLKLTTRAQLGAKSEQLLKKGKSIPDVLLVDIIVNAINEIPVNQDCILDGFPMTLNQAQLLEEALTGCNRNLTEVERKKAQKSTLAIDPATSKEIPLPSPAFDFVILLDVSDTSSMSRMNDIIAEELSYKTAHEDISQRVAAENQDKDGDQNLRDQIQHRIIGFLDNWPLLEQWFSEPENILIKINAEIDKESLCEKVKEILTTEIAKKKNKVEKKLEEKEAEKKAAASLAELPLPTPPPAPPPEPEKEKEIHQSHVASKTPTAKGKPQSEAPHGKQESLQEGKGKKGETALKRKGSPKGKSSGGKVPVKKSPADSTDTSPVAIVPQPPKPGSEEWVYVNEPVPEEMPLFLVPYWELIENSYINTIKTVLRHLREDQHTVLAYLYEIRTSFQEFLKRPDHKQDFVAQWQADFNSLPDDLWDDEETKAELHQRVNDLRDRLWDICDARKEEAEQERLDIINESWLQDTLGMTMNHFFSLMQAELNRFQDTKRLLQDYYWGMESKIPVEDNKRFTRIPLVQLDSKDNSESQLRIPLVPRISISLETVTPKPKTKSVLKGKMDNSLENVESNFEADEKLVMDTWQQASLAVSHMVAAEIHQRLMEEEKENQPADPKEKSPQMGANKKVKKEPPKKKQEDKKPKGKSPPMAEATPVIVTTEEIAEIKRKNELRVKIKEEHLAALQFEEIATQFRLELIKTKALALLEDLVTKVVDVYKLMEKWLGERYLNEMASTEKLTDVARYHIETSTKIQNELYLSQEDFFINGNIKVFPDPPPSIRPPPVEKEEDGTLTIEQLDSLRDQFLDMAPKGIIGNKAFTDILIDLVTLNLGTNNFPSNWMHLTQPELQELTSLLTVNSEFVDWRKFLLVTSMPWPIPLEEELLETLQKFKAVDKEQLGTITFEQYMQAGLWFTGDEDIKIPENPLEPLPFNRQEHLIEFFFRLFADYEKDPPQLDYTQMLLYFACHPDTVEGVYRALSVAVGTHVFQQVKASIPSAEKTSSTDAGPAEEFPEPEENAAREERKLKDDTEKREQKDEEIPENANNEKMSMETLLKVFKGGSEAQDSNRFASHLKIENIYAEGFIKTFQDLGAKNLEPIEVAVLLKHPFIQDLISNYSDYKFPDIKIILQRSEHVQGSDGERSPSRHTEEKK", "length": 1822 }, "evidence": [ { "id": "A0A8V0YIE9", "url": "https://omabrowser.org/oma/group/A0A8V0YIE9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9R095-1", "protein_name": "Sperm flagella and cilia-associated protein 2", "gene_name": "Spef2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSEILCQWLNQELKVSRTVSPKSFAKTFSNGYLIGEVLFKFELQSDFSEFSESRVSTAKLNNFSRLQPTLHLLGVQFDQNVAQSIITEKPGAATKLLYQLYIALQKKKKTGLTGLEIQTMQPQTNQRLQALKSEAFRERLKNLIPRQTDFNLMRVTCRFQEKCKQMKEDLARMHFEKFEKIQKLEEEQRHFNIEKQRLNRRRQNEIMAKIQAAIIQIPKPEPNRTLKAIEAQKLMKKKKEAEDVANEIKKFEALIKKDLQTRESISKTSLDTIDQTAAELLNTYSDDDYIKKIQKRLEEDAFAREQREKRRRRLLMDQLIAHEAQEEAYREEQLIHRLMRQSQQERRIAVQLMHVRHEKEVLWQNRIFREKQFEERRLKDFQDALDREAALTKQAKIDFAEQTLRAKEIHEKIAMERAQQRYEKHYGICAEILDQILDLCTKVADYRLLTNNLIPHKMMRDWKELFFSGNPIYEQTSHTHGQTESTEDHHVELNKRNLLDSKDYEDYKNMTGEWALPEDMANSSPPSNNNILGHVLLRLIENSYPSEKEVADTELPSFAVKGCLLGKTLSGKTTILKALQNDIPIQVLSIDTLVQEAIQAFNDGEKSSKAPSMHEDVKGDPEVDQKEMIIPQDKNELTDTQVPGEAAPQKEGTKSSDFEQFRPSNSFLSLSMRAQLGAKSELMLRRGKSVPDVLLVNILVNAIKKIPVNQSWVLDGFPMTVNQAKLLEEALTGYKRKSLQLKKKKAQMPTLALSPTTSKEVPFLPSAFDFAILLDISDNSSLARINDIIAKEISHEISHENVSGPTITSSEEKSEDRNLRDHIQHRIVGFLDNWPLLEEWFTEPRNILKKVNAEIDEAFLCQKIKEIFATEVSNKKIKVEKKLEEKETEKKSAVSPTEPPTPTPPLASEAEKEKEVHQAKPSGKGKTQSVSPKGKAQGGKISVKKSPIDSTEVSPTLIAMPTTKPGSEEWVYVTEPIPEELPSFLVPYWELIEKTYISHIKTVLRQLRESQHTVLSYLYETRTSFQEFLRRPDHKQDFVSQWQADFNSVPEDLWEDEETKAELHQRVNDLRDRLWDICEARKEEAEQERLDIINESWLQDYIGITMNHFFSLMQAEVNRFQDTKRLLQDYYRAMESRIPLEDNKKFTRIPLVQLDGKEISEHQLRIPLVPRISSSPENVSMRPKVKALLKGRFDPPLESLEANFEGDEKIVLDTWQQASLAISQMVAAEVHQRLAEEEKEQPQLDPKEKSPQSGTNKKAKKEKEQAKKEKEQAKKEKEQAKKEKEPPKKKMAEKKGKGKSSPVVEVSPVTITPEEMAEMERKNELKLKIKEEHLAALQTEEQATQFRLELIKSKALSILEDLVTKVIEVYRFMEKWLGKRYLNEMASIQKLTEVARYHIETATKIQNEIYLSQEDFYINGDIKVFPDPPPPTRPPPVEKEENGTLTIEQLDNLRDQFLDMAPKGIIGNKAFTDILLDLVTLNLGTNNLSSSWMHLTQLDLQEITSLLTVNTEFVDWRKFLMVAAMPWPIPLEEELLETLQRFKATDEAQTGTITFEQYKQAGLWFSGDEDIKIPENPLEPLPFNRQEHLIEFFFRLFADSEKDPPQLDYTQMLLYFACHPDTLEGVYRALSVAVGTHIFRQVETPMLTAEKTSISSVSPNEEFPEAEENSTREELKEEKDERDQKEEEIPENANTEKISMETLLKVFGGGNEVLDANRFASYLKTENIYSENLIKTFQDLGAKNLEPIEVNILLKHPYIQDLITNYVDYKIPDIKMILQRSEHAQGSDGERSPSRLTDEKK", "length": 1801 }, "evidence": [ { "id": "A0A8V0YIE9", "url": "https://omabrowser.org/oma/group/A0A8V0YIE9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIE9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIE9" } ], "pmid": "" }, { "name": "manchette", "id": "GO:0002177", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002177", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIE9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIE9" } ], "pmid": "" }, { "name": "sperm midpiece", "id": "GO:0097225", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097225", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIE9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIE9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "sperm axoneme assembly", "id": "GO:0007288", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007288", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIE9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIE9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1125, "end_pos": 1127, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1143, "end_pos": 1145, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1161, "end_pos": 1163, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1421, "end_pos": 1423, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1855, "end_pos": 1857, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1902, "end_pos": 1904, "annotation": "n_glycosylation_sequon" }, { "start_pos": 523, "end_pos": 525, "annotation": "n_glycosylation_sequon" }, { "start_pos": 537, "end_pos": 539, "annotation": "n_glycosylation_sequon" }, { "start_pos": 62, "end_pos": 64, "annotation": "n_glycosylation_sequon" }, { "start_pos": 642, "end_pos": 644, "annotation": "n_glycosylation_sequon" }, { "start_pos": 657, "end_pos": 659, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YIE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIE9" }, { "id": "PS50021", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50021" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Calponin-homology (CH)", "eco_id": "ECO_0000259", "start_pos": 1, "end_pos": 105, "start_aa": "Met", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1125, "end_pos": 1127 }, { "start_pos": 1143, "end_pos": 1145 }, { "start_pos": 1161, "end_pos": 1163 }, { "start_pos": 1421, "end_pos": 1423 }, { "start_pos": 1855, "end_pos": 1857 }, { "start_pos": 1902, "end_pos": 1904 }, { "start_pos": 523, "end_pos": 525 }, { "start_pos": 537, "end_pos": 539 }, { "start_pos": 62, "end_pos": 64 }, { "start_pos": 642, "end_pos": 644 }, { "start_pos": 657, "end_pos": 659 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YIF0-1", "uniprot_ac": "A0A8V0YIF0", "uniprot_id": "A0A8V0YIF0_CHICK", "mass": { "chemical_mass": 38907.0, "monoisotopic_mass": 38907.0 }, "refseq": { "ac": "XP_015145826", "name": "putative C->U-editing enzyme APOBEC-4", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015145826" }, "gene_names": [ { "name": "APOBEC4", "type": "recommended", "evidence": [ { "id": "A0A8V0YIF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIF0" } ] }, { "name": "APOBEC4", "type": "synonym", "evidence": [ { "id": "XP_015145826", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015145826" } ] } ], "protein_names": [ { "name": "Apolipoprotein B mRNA editing enzyme catalytic polypeptide like 4", "type": "synonym", "evidence": [ { "id": "A0A8V0YIF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIF0/entry#names_and_taxonomy" } ] }, { "name": "putative C->U-editing enzyme APOBEC-4", "type": "synonym", "evidence": [ { "id": "XP_015145826", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015145826" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052539.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015145826.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015145826", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015145826" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIF0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIF0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "APOBEC4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIF0", "locus": { "chromosome": "8", "start_pos": 7630758, "end_pos": 7633036, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010011540", "url": "https://www.ensembl.org/id/ENSGALG00010011540" } ] } } ], "crossref": [ { "id": "A0A8V0YIF0", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YIF0", "database": "AlphaFoldDB", "categories": [] }, { "id": "100858926", "url": "https://www.ncbi.nlm.nih.gov/gene/100858926", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002125", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002125", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038953", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038953", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:100858926", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100858926", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PASAWNR", "url": "https://omabrowser.org/oma/group/PASAWNR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YIF0", "url": "https://www.orthodb.org/?gene=A0A8V0YIF0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR35672", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR35672", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR35672:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR35672:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF18775", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18775", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015145826", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015145826", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YIF0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIF0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YIF0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIF0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNPGQKIFQEYLTNQGTVVKPYCWQTWSQTCAKCPYHIRTGEEARVPYAEFLRAFGFPCRTTAHPQTHHLLFYELKSFSGTVVQKGHATSCAEQDNHPESMLFEADGYLDAVIHAYRNIGCITLYSNYSPCNEAYHCCVSKIYNFLLKYPETTLCLYFSQPYHTEDSFPTATWNRQALHSLASLWPQVTLQPLPTGTRCHLLSNFVYGIPGSMLQHPASPPGTLSDRQNPHQINNLRGVKTYCRKAFPQATHGEPAVQQNPKAFSFPHPAFQQPLPVTKGSLPHPVSQSHSVLFPGLFLSSHREHLHPRPVNVVRHLKMPKELISESHYPEALLASRNRQRR", "length": 342, "header": "tr|A0A8V0YIF0-1|A0A8V0YIF0_CHICK Isoform 1 of Apolipoprotein B mRNA editing enzyme catalytic polypeptide like 4 OS=Gallus gallus OX=9031 GN=APOBEC4 PE=4 SV=1 CANONICAL=A0A8V0YIF0-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YIF0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIF0/entry#A0A8V0YIF0-1", "sequence": { "sequence": "MNPGQKIFQEYLTNQGTVVKPYCWQTWSQTCAKCPYHIRTGEEARVPYAEFLRAFGFPCRTTAHPQTHHLLFYELKSFSGTVVQKGHATSCAEQDNHPESMLFEADGYLDAVIHAYRNIGCITLYSNYSPCNEAYHCCVSKIYNFLLKYPETTLCLYFSQPYHTEDSFPTATWNRQALHSLASLWPQVTLQPLPTGTRCHLLSNFVYGIPGSMLQHPASPPGTLSDRQNPHQINNLRGVKTYCRKAFPQATHGEPAVQQNPKAFSFPHPAFQQPLPVTKGSLPHPVSQSHSVLFPGLFLSSHREHLHPRPVNVVRHLKMPKELISESHYPEALLASRNRQRR", "length": 342, "header": "tr|A0A8V0YIF0-1|A0A8V0YIF0_CHICK Isoform 1 of Apolipoprotein B mRNA editing enzyme catalytic polypeptide like 4 OS=Gallus gallus OX=9031 GN=APOBEC4 PE=4 SV=1 CANONICAL=A0A8V0YIF0-1" }, "locus": { "chromosome": "8", "start_pos": 7632357, "end_pos": 7631332, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027612.1", "url": "https://www.ensembl.org/id/ENSGALT00010027612.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015817.1", "url": "https://www.ensembl.org/id/ENSGALP00010015817.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:100858926", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100858926", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "F1S657-1", "protein_name": "Apolipoprotein B mRNA editing enzyme catalytic polypeptide like 4", "gene_name": "APOBEC4", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEPLYEEYLANCGTIVKPYYWLSFSLDCSNCPYHIRTGEEARVPYTEFYQLFGFPYGPTGPQTKHLAFYELRPSSGSLVQKGHASSCTGNDTHPESMLFERNGYFDSAIRNNNGIRHIILYSNNSPCNEANHCCISKMYNFLRMYPDVTLSIYFSQLYHTEAEFPASAWNREALRSLASLWPQVTLSPISGGIWHSLLHNFVSGVSGWPLFQPILTGRALADRHNAYEINAITGVKPNFTDVLPQVKENQNIKTQAALEAYPLNNVFPRQSFQMTSGQLQPNLTLDPRVPVVFVLVPFRELPPIYVRQNPHKPRNIVRHFNLPQMSFQETNDLRRPPRGGPAESAEITEQFASSKVADEKKKTGKK", "length": 366 }, "evidence": [ { "id": "A0A8V0YIF0", "url": "https://omabrowser.org/oma/group/A0A8V0YIF0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3MWJ4-1", "protein_name": 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}, { "id": "PS51747", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51747" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CMP/dCMP-type deaminase", "eco_id": "ECO_0000259", "start_pos": 65, "end_pos": 181, "start_aa": "Pro", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 127, "end_pos": 129 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YIF3-1", "uniprot_ac": "A0A8V0YIF3", "uniprot_id": "A0A8V0YIF3_CHICK", "mass": { "chemical_mass": 43889.0, "monoisotopic_mass": 43889.0 }, "refseq": {}, "gene_names": [ { "name": "SASH3", "type": "recommended", "evidence": [ { "id": "A0A8V0YIF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIF3" } ] } ], "protein_names": [ { "name": "SAM and SH3 domain containing 3", "type": "synonym", "evidence": [ { "id": "A0A8V0YIF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIF3/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIF3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIF3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SASH3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIF3", "locus": { "chromosome": "4", "start_pos": 1590158, "end_pos": 1594299, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010014813", "url": "https://www.ensembl.org/id/ENSGALG00010014813" } ] } } ], "crossref": [ { "id": "A0A8V0YIF3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YIF3", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd09560", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09560", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd11968", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11968", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001660", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001660", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013761", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013761", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR021090", "url": "https://www.ebi.ac.uk/interpro/entry/IPR021090", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035721", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035721", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036028", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036028", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YIF3", "url": "https://www.orthodb.org/?gene=A0A8V0YIF3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YRK8", "url": "https://www.orthodb.org/?gene=A0A8V0YRK8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12301", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12301", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12301:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12301:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00536", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00536", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07653", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07653", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12485", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12485", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YIF3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIF3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YIF3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIF3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YRK8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRK8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YRK8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRK8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLRRKPSNAGEKEPGHRKLSLQRSSSFKDFAKSKVSSPVTSEKEFNLEENIPEDEPSSAGPEEAARSSSSGMKLGKKWRAVISRTMNRKMGRMAVRALAEGKQAEVEEEGCPSPLPSAGTEEPSHEKMPLSYVEMEEDAHPSVSRQLSTGSEGLSPGPTSQDSPRLEDGSPAYTGPFCGRARVHTDFTPSPYDKDSLKLRKGDIIGIIEKPPVGTWTGLLNNKVGSFKFIYVDVIPEEAAPTRKSRGQGKSKRLKPKTLHELLERINLQLRAVGTRGVGAGLGSPSCCSLPQEHTSTLLLNGYQTLEDFKELRETHLNELNITDPQHRAKLLTAAELLLDYDTSSEAEEGDGTAEQHSPSEPKGDIPRDSGCFEGSETLDSSREEAELPSPAGQPQALSLAESS", "length": 404, "header": "tr|A0A8V0YIF3-1|A0A8V0YIF3_CHICK Isoform 1 of SAM and SH3 domain containing 3 OS=Gallus gallus OX=9031 GN=SASH3 PE=1 SV=1 CANONICAL=A0A8V0YIF3-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YIF3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIF3/entry#A0A8V0YIF3-1", "sequence": { "sequence": "MLRRKPSNAGEKEPGHRKLSLQRSSSFKDFAKSKVSSPVTSEKEFNLEENIPEDEPSSAGPEEAARSSSSGMKLGKKWRAVISRTMNRKMGRMAVRALAEGKQAEVEEEGCPSPLPSAGTEEPSHEKMPLSYVEMEEDAHPSVSRQLSTGSEGLSPGPTSQDSPRLEDGSPAYTGPFCGRARVHTDFTPSPYDKDSLKLRKGDIIGIIEKPPVGTWTGLLNNKVGSFKFIYVDVIPEEAAPTRKSRGQGKSKRLKPKTLHELLERINLQLRAVGTRGVGAGLGSPSCCSLPQEHTSTLLLNGYQTLEDFKELRETHLNELNITDPQHRAKLLTAAELLLDYDTSSEAEEGDGTAEQHSPSEPKGDIPRDSGCFEGSETLDSSREEAELPSPAGQPQALSLAESS", "length": 404, "header": "tr|A0A8V0YIF3-1|A0A8V0YIF3_CHICK Isoform 1 of SAM and SH3 domain containing 3 OS=Gallus gallus OX=9031 GN=SASH3 PE=1 SV=1 CANONICAL=A0A8V0YIF3-1" }, "locus": { "chromosome": "4", "start_pos": 1594223, "end_pos": 1591080, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010035650.1", "url": "https://www.ensembl.org/id/ENSGALT00010035650.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020690.1", "url": "https://www.ensembl.org/id/ENSGALP00010020690.1" } ] } }, { "isoform_ac": "A0A8V0YRK8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIF3/entry#A0A8V0YRK8-1", "sequence": { "sequence": "MVEGSAAVLGVSREPPPAAQRALTPSPCPQLSLQRSSSFKDFAKSKVSSPVTSEKEFNLEENIPEDEPSSAGPEEAARSSSSGMKLGKKWRAVISRTMNRKMGRMAVRALAEGKQAEVEEEGCPSPLPSAGTEEPSHEKMPLSYVEMEEDAHPSVSRQLSTGSEGLSPGPTSQDSPRLEDGSPAYTGPFCGRARVHTDFTPSPYDKDSLKLRKGDIIGIIEKPPVGTWTGLLNNKVGSFKFIYVDVIPEEAAPTRKSRGQGKSKRLKPKTLHELLERINLQEHTSTLLLNGYQTLEDFKELRETHLNELNITDPQHRAKLLTAAELLLDYDTASSEAEEGDGTAEQHSPSEPKGDIPRDSGCFEGSETLDSSREEAELPSPAGQPQALSLAESS", "length": 394, "header": "tr|A0A8V0YRK8-1|A0A8V0YRK8_CHICK Computationally mapped isoform of SAM and SH3 domain containing 3 OS=Gallus gallus OX=9031 GN=SASH3 PE=1 SV=1 CANONICAL=A0A8V0YIF3-1" }, "locus": { "chromosome": "4", "start_pos": 1593130, "end_pos": 1591080, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010035642.1", "url": "https://www.ensembl.org/id/ENSGALT00010035642.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020688.1", "url": "https://www.ensembl.org/id/ENSGALP00010020688.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 159, "start_aa": "Thr", "end_pos": 159, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr159", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIF3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIF3" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIF3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIF3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "positive regulation of B cell proliferation", "id": "GO:0030890", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030890", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIF3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIF3" } ], "pmid": "" }, { "name": "regulation of intracellular signal transduction", "id": "GO:1902531", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902531", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIF3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIF3" } ], "pmid": "" }, { "name": "positive regulation of adaptive immune response", "id": "GO:0002821", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002821", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIF3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIF3" } ], "pmid": "" }, { "name": "positive regulation of immunoglobulin production", "id": "GO:0002639", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002639", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIF3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIF3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 321, "end_pos": 323, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YIF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIF3" }, { "id": "PS50002", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50002" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SH3", "eco_id": "ECO_0000259", "start_pos": 176, "end_pos": 237, "start_aa": "Pro", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 159 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 321, "end_pos": 323 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YIG1-1", "uniprot_ac": "A0A8V0YIG1", "uniprot_id": "A0A8V0YIG1_CHICK", "mass": { "chemical_mass": 53869.0, "monoisotopic_mass": 53869.0 }, "refseq": { "ac": "XP_416339", "name": "putative transporter SVOPL isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_416339" }, "gene_names": [ { "name": "SVOPL", "type": "recommended", "evidence": [ { "id": "A0A8V0YIG1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIG1" } ] }, { "name": "SVOPL", "type": "synonym", "evidence": [ { "id": "XP_416339", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_416339" } ] } ], "protein_names": [ { "name": "SVOP like", "type": "synonym", "evidence": [ { "id": "A0A8V0YIG1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIG1/entry#names_and_taxonomy" } ] }, { "name": "putative transporter SVOPL isoform X2", "type": "synonym", "evidence": [ { "id": "XP_416339", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_416339" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_416339.4. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_416339", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_416339" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIG1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIG1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SVOPL", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIG1", "locus": { "chromosome": "1", "start_pos": 56421590, "end_pos": 56401223, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013237", "url": "https://www.ensembl.org/id/ENSGALG00010013237" } ] } } ], "crossref": [ { "id": "A0A8V0YIG1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YIG1", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd17442", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd17442", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "418105", "url": "https://www.ncbi.nlm.nih.gov/gene/418105", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR005828", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005828", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011701", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011701", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020846", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020846", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036259", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036259", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:418105", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418105", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PTWIGVC", "url": "https://omabrowser.org/oma/group/PTWIGVC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YIG1", "url": "https://www.orthodb.org/?gene=A0A8V0YIG1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YJ78", "url": "https://www.orthodb.org/?gene=A0A8V0YJ78", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23511", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23511", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23511:SF45", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23511:SF45", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00083", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00083", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07690", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07690", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_416339", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_416339", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YIG1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIG1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YIG1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIG1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJ78", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ78", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJ78-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ78-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MATAPKEAANTIALEEIHTEGPEPPKGQKTFTVEEAVETIGFGRFHIALFLIMGSTVVAEAMEIMLIAVVSPLIRCEWQLQDWQVALVTTMVFFGYMVFSIVLGLLADRYGRWKILLLSFLWGAYFSLLTSFAPSYIWFVFLRTMVGGGVSGHAQGLIIKTEFLPTKYRGYMLPLSQVFWLAGSLLIIGLASVVNPTIGWRWLIRIASIPGIILIMVFKFIPESARYNVSTGNNVAALATLQRIAKMNRATMPEGALQEPPKERRGRFKDLLHPKYLRTTLQIWIIWLGIAFAYYGVILASAELLERDLGCTSRTPPSENAGPVSEESRSPCYCHPFGPSAYRTMIISTAGEIALNPLNILGINFLGRRLSLCITMGCTALFFLLLNVCTSSAGMTGFLFMLRALVSANFNTIYIYTAEVYPTTMRALGMGTSGSLCRVGAMVAPFISQVLMSASFLGALCLFSSVCVVCAISAFTLPIETKGRALQQVK", "length": 490, "header": "tr|A0A8V0YIG1-1|A0A8V0YIG1_CHICK Isoform 1 of SVOP like OS=Gallus gallus OX=9031 GN=SVOPL PE=3 SV=1 CANONICAL=A0A8V0YIG1-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YIG1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIG1/entry#A0A8V0YIG1-1", "sequence": { "sequence": "MATAPKEAANTIALEEIHTEGPEPPKGQKTFTVEEAVETIGFGRFHIALFLIMGSTVVAEAMEIMLIAVVSPLIRCEWQLQDWQVALVTTMVFFGYMVFSIVLGLLADRYGRWKILLLSFLWGAYFSLLTSFAPSYIWFVFLRTMVGGGVSGHAQGLIIKTEFLPTKYRGYMLPLSQVFWLAGSLLIIGLASVVNPTIGWRWLIRIASIPGIILIMVFKFIPESARYNVSTGNNVAALATLQRIAKMNRATMPEGALQEPPKERRGRFKDLLHPKYLRTTLQIWIIWLGIAFAYYGVILASAELLERDLGCTSRTPPSENAGPVSEESRSPCYCHPFGPSAYRTMIISTAGEIALNPLNILGINFLGRRLSLCITMGCTALFFLLLNVCTSSAGMTGFLFMLRALVSANFNTIYIYTAEVYPTTMRALGMGTSGSLCRVGAMVAPFISQVLMSASFLGALCLFSSVCVVCAISAFTLPIETKGRALQQVK", "length": 490, "header": "tr|A0A8V0YIG1-1|A0A8V0YIG1_CHICK Isoform 1 of SVOP like OS=Gallus gallus OX=9031 GN=SVOPL PE=3 SV=1 CANONICAL=A0A8V0YIG1-1" }, "locus": { "chromosome": "1", "start_pos": 56421375, "end_pos": 56404395, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031799.1", "url": "https://www.ensembl.org/id/ENSGALT00010031799.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018616.1", "url": "https://www.ensembl.org/id/ENSGALP00010018616.1" } ] } }, { "isoform_ac": "A0A8V0YJ78-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIG1/entry#A0A8V0YJ78-1", "sequence": { "sequence": "MATAPKEAANTIALEEIHTEGPEPPKGQKTFTVEEAVETIGFGRFHIALFLIMGSTVVAEAMEIMLIAVVSPLIRCEWQLQDWQVALVTTMVFFGYMVFSIVLGLLADRYGRWKILLLSFLWGAYFSLLTSFAPSYIWFVFLRTMVGGGVSGHAQGLIIKTEFLPTKYRGYMLPLSQVFWLAGSLLIIGLASVVNPTIGWRWLIRIASIPGIILIMVFKFIPESARYNVSTGNNVAALATLQRIAKMNRATMPEGALQEPPKERRGRFKDLLHPKYLRTTLQIWIIWLGIAFAYYGVILASAELLERDLGCTSRTPPSENAGPVSEESRSPCYCHPFGPSAYRTMIISTAGEIALNPLNILGINFLGRRLSLCITMGCTALFFLLLNVCTSSAGMTGFLFMLRALVSANFNTIYIYTAEVYPTTMRALGMGTSGSLCRVGAMVAPFISQVLMSASFLGALCLFSSVCVVCAISAFTLPIETKGRALQVCMGSPGASPCLQAT", "length": 502, "header": "tr|A0A8V0YJ78-1|A0A8V0YJ78_CHICK Computationally mapped isoform of SVOP like OS=Gallus gallus OX=9031 GN=SVOPL PE=4 SV=1 CANONICAL=A0A8V0YIG1-1" }, "locus": { "chromosome": "1", "start_pos": 56419293, "end_pos": 56404395, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031797.1", "url": "https://www.ensembl.org/id/ENSGALT00010031797.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018614.1", "url": "https://www.ensembl.org/id/ENSGALP00010018614.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:418105", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418105", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2M8F4-1", "protein_name": "Transporter SVOPL isoform X2", "gene_name": "Svopl", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAAKQTEPVTIISLRKLSQASPEPQQKETKTFTVEDAVETIGFGRFHIALFLIMGSTGVVEAMEIMLIAVVSPVIRCEWHLENWQVAFVTTMVFFGYMVSSILFGLLADRYGRWKILLLSFLWGAYFSLLTSFSPSYVWFVFLRTMVGCGVSGHAQGLIIKTEFLPTKYRGYMLPLSQVFWLAGSLLIISLASVLIPTIGWRWLIRVASIPGIILIMAFKFIPESARFNVSTGNTQAALDTLESIARMNRSVMPEGQLVEPILEKRGRFADLLDSKYLRTTLQIWVIWLGISFAYYGVILASAELLERDLVCGSKSGSEPEVVVTTGETEGSRSPCYCHLFAPSDYRTMIISTLGEIALNPLNILGINFLGRRLSLSITMGCTALFFLLLNICTSSAGLIGFLFMLRALVAANFNTIYIYTAEVYPTPMRALGMGTSGSLCRIGAMVAPFISQVLMSASFLGALCLFSSVCVVCAISAFTLPIETKGRALQQMK", "length": 494 }, "evidence": [ { "id": "A0A8V0YIG1", "url": "https://omabrowser.org/oma/group/A0A8V0YIG1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "D4A9T9-1", "protein_name": "SVOP like", "gene_name": "Svopl", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAAKQTEPVTIISLRKLSQAAPEPQQKETKTFTVEDAVETIGFGRFHIALFLIMGSTGVVEAMEIMLIAVVSPVIRCEWQLENWQVAFVTTMVFFGYMVSSILFGLLADRYGRWKILLLSFLWGAYFSLLTSFSPSYIWFVFLRTMVGCGVSGHAQGLIIKTEFLPTKYRGYMLPLSQVFWLAGSLLIISMASVVIPTIGWRWLIRIASIPGIILIMAFKFIPESARFNVSTGNTQAALDTLESIAKMNRSVMPEGRLVEPILEKRGRFADLLESKYLRTTLQIWIIWLGISFAYYGVILASAELLERDLVCGSKSESEPEVVENMGDAEEGRSPCYCHMFAPSDYRTMIISTLGEIALNPLNILGINFLGRRLSLSITMGCTALFFLLLNICTSSAGLIGFLFMLRALVAANFNTIYIYTAEVYPTPMRALGMGTSGSLCRIGAMVAPFISQVLMSASFLGALCLFSSVCVVCAISAFTLPIETKGRALQQIK", "length": 494 }, "evidence": [ { "id": "A0A8V0YIG1", "url": "https://omabrowser.org/oma/group/A0A8V0YIG1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E1BGJ7-1", "protein_name": "V-type proton ATPase subunit a", "gene_name": "ATP6V0A4", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MASIFRSEEMCLSQLFLQVEAAYCCVAELGELGLVQFKDLNVKESRFQRKFVNEVRRCESLERILRFLEDQMQDEIEIQVPEKSPLTPLPREMIILETALEKLEGELQEANQNYQALKKNFLELTEFKHLLKKTQDFFETEANLADDFFVEDTSGLLELRPTPAYISGKLGFTAGVVNRERMASFERLLWRICRGNIYVKFSEMDTVLEDPVTREEIKKNIFIIFYQGEQLREKIKKVCDGYRATVYPCPELALERREMLQGVNMRLEDLLTVLTQTESHRQSLLQEAAANWHSWVIKVQKMKAIYHILNLCNIDITQQCVIAEIWFPVADTVRIRRALEQGVELSGSSMVPILTAVQSKTAPPTFNRTNKFTAGFQNIVDAYGIGSYREMNPAPYTIITFPFLFAVMFGDCGHGTVMFLAALWMVLNEKHLLAQKSTNEIWNTFFHGRYLILLMGIFSIYTGLIYNDCFAKSLNIFGSSWSVQPMFRNGTWSMQVLKTNPLLQLDPAVPGVYSGNPYPFGIDPIWNLASNKLTFLNSYKMKMSVILGIVQMVFGVILSLFNYRFFRNTLNIILQFIPEMIFILSLFGYLVFMIIFKWCSFDVSVSRRAPSILIHFINMFLFNYKDSSNVPLYQHQQKVQSFFVIMALISVPWMLLIKPFILRANHRKSQLQASRIPEDTTENTEGDNSGHIASVGAHGAQDDHDQEFNFGDIFVHQAIHTIEYCLGCISNTASYLRLWALSLAHAQLSEVLWTMVMHIGLRTRGWGGLVGVFIIFAVFAVLTVAILLIMEGLSAFLHALRLHWVEFQNKFYTGAGYKFSPFSFKQILDGTAEE", "length": 834 }, "evidence": [ { "id": "A0A8V0YIG1", "url": "https://omabrowser.org/oma/group/A0A8V0YIG1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q6PDF3-1", "protein_name": "Putative transporter SVOPL", "gene_name": "Svopl", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAKQTEPVTIISLRKLSQAAPEPQQKETKTFTVEDAVETIGFGRFHIALFLIMGSTGVVEAMEIMLIAVVSPVIRCEWQLENWQVAFVTTMVFFGYMVSSILFGLLADRYGRWKILLLSFLWGAYFSLLTSFSPSYIWFVFLRTMVGCGVSGHAQGLIIKTEFLPTKYRGYMLPLSQVFWLAGSLLIISMASVVIPTIGWRWLIRIASIPGIILIMAFKFIPESARFNVSTGNTQAALNTLESIAKMNRSVMPEGQLVEPILEKRGRFADLLDSKYLRTTLQIWIIWLGISFAYYGVILASAELLERDLVCGSKSESEPEVVETTGDSGEGLSPCYCHIFAPSDYRTMIISTLGEIALNPLNILGINFLGRRLSLSITMGCTALFFLLLNICTSSAGLIGFLFMLRALVAANFNTIYIYTAEVYPTPMRAIGMGTSGSLCRIGAMVAPFISQVLMSASFLGALCLFSSVCVVCAISAFTLPIETKGRALQQIK", "length": 494 }, "evidence": [ { "id": "A0A8V0YIG1", "url": "https://omabrowser.org/oma/group/A0A8V0YIG1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8N434-1", "protein_name": "Putative transporter SVOPL", "gene_name": "SVOPL", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MATKPTEPVTILSLRKLSLGTAEPQVKEPKTFTVEDAVETIGFGRFHIALFLIMGSTGVVEAMEIMLIAVVSPVIRCEWQLENWQVALVTTMVFFGYMVFSILFGLLADRYGRWKILLISFLWGAYFSLLTSFAPSYIWFVFLRTMVGCGVSGHSQGLIIKTEFLPTKYRGYMLPLSQVFWLAGSLLIIGLASVIIPTIGWRWLIRVASIPGIILIVAFKFIPESARFNVSTGNTRAALATLERVAKMNRSVMPEGKLVEPVLEKRGRFADLLDAKYLRTTLQIWVIWLGISFAYYGVILASAELLERDLVCGSKSDSAVVVTGGDSGESQSPCYCHMFAPSDYRTMIISTIGEIALNPLNILGINFLGRRLSLSITMGCTALFFLLLNICTSSAGLIGFLFMLRALVAANFNTVYIYTAEVYPTTMRALGMGTSGSLCRIGAMVAPFISQVLMSASILGALCLFSSVCVVCAISAFTLPIETKGRALQQIK", "length": 492 }, "evidence": [ { "id": "A0A8V0YIG1", "url": "https://omabrowser.org/oma/group/A0A8V0YIG1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIG1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIG1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "transmembrane transporter activity", "id": "GO:0022857", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022857", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIG1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIG1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 228, "end_pos": 230, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YIG1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIG1" }, { "id": "PS50850", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50850" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Major facilitator superfamily (MFS) profile", "eco_id": "ECO_0000259", "start_pos": 49, "end_pos": 482, "start_aa": "Leu", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 228, "end_pos": 230 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YIG6-1", "uniprot_ac": "A0A8V0YIG6", "uniprot_id": "A0A8V0YIG6_CHICK", "mass": { "chemical_mass": 100929.0, "monoisotopic_mass": 100929.0 }, "refseq": {}, "gene_names": [ { "name": "HLCS", "type": "recommended", "evidence": [ { "id": "A0A8V0YIG6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIG6" } ] } ], "protein_names": [ { "name": "Holocarboxylase synthetase", "type": "synonym", "evidence": [ { "id": "A0A8V0YIG6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIG6/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIG6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIG6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "HLCS", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIG6", "locus": { "chromosome": "1", "start_pos": 106955115, "end_pos": 107069358, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013104", "url": "https://www.ensembl.org/id/ENSGALG00010013104" } ] } } ], "crossref": [ { "id": "A0A8V0YIG6", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YIG6", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd16442", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16442", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR003142", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003142", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004143", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004143", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004408", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004408", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045864", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045864", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YIG6", "url": "https://www.orthodb.org/?gene=A0A8V0YIG6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YQA6", "url": "https://www.orthodb.org/?gene=A0A8V0YQA6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12835", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12835", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12835:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12835:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02237", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02237", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF03099", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03099", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-196780", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-196780", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YIG6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIG6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YIG6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIG6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQA6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQA6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQA6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQA6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLITLCYLYLWARWGPCSAALIRRTVRRLHRSRCSFIFCCSAGPSAPPAHPPRRPAPPEERVCLRIGNKVFFTDETQLLDDLNRWSLLLISPFIYPEKLLETEHIAFVTESVSAQADNLQKLPVSSKEIVKWSDYCSPLAYKPGEPYKLIAEASVDNFSNLGIAFMEDRLQMDNGMVPCKIVSVHLQETTLKELKQVTPSMKEKSVSITQMNEVTPDTFGTTVKTQLGVSESAGQGDSEAKEEKSKLVKENGDESNSLSDKETGFGEHHHLHLSSCRECLQLENSTIESVRFASAEDIPELPDDCNSKLEENGDCLTTGIKRVNLAGKPPNILIYVGSGTAKVDFEQVKSIIQECVDTDSYTIYQLHEEQVLKAPWIDNSLLLIIATEGPISEKNQKQFMKFLSKGGKILGLSSSFTFDGIQIKRKDKLKRTVHELVVSKMDSTEMKLNLLISGCIFEVAMKEGSSKVKPLSRLNNADKDIVIVYLPYGDNGGEAILSQVHLELDTNSVDIQTEEDFNLLKMSNPKRYEVLKEILISLGLSCELSEIPMLTPIYLLSSDEVLFYFPCPQEIHLTFLKWLEENVNVEGLIESSKVSLKFVSSCESKMEITPSLMSVITKMGNFSSEHFSLETYQQNLQTKKLGKILFFTEVTTTTMNLLDGLMFKLPEEMGLIAIAVRQTQGKGRGGNVWLSPIGCALSTLHITIPLHSNLGQRIPFIQHLVSLAVVESVRSIPGYEDIDLRVKWPNDIYYSDLMKLGGVLVTSTLIETTFHILIGFGFNVNNSNPTICINDLITKFNKEEGTNLKALTADCLIARTVTVLERLIDIFQEKGPNGVLPRYYKYWVHSGKQVRLHNEEGPLAWIVGIDDYGFLQVHEEGKGVESVHPDGNSFDMLKNLIIPKH", "length": 901, "header": "tr|A0A8V0YIG6-1|A0A8V0YIG6_CHICK Isoform 1 of Holocarboxylase synthetase OS=Gallus gallus OX=9031 GN=HLCS PE=3 SV=1 CANONICAL=A0A8V0YIG6-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YIG6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIG6/entry#A0A8V0YIG6-1", "sequence": { "sequence": "MLITLCYLYLWARWGPCSAALIRRTVRRLHRSRCSFIFCCSAGPSAPPAHPPRRPAPPEERVCLRIGNKVFFTDETQLLDDLNRWSLLLISPFIYPEKLLETEHIAFVTESVSAQADNLQKLPVSSKEIVKWSDYCSPLAYKPGEPYKLIAEASVDNFSNLGIAFMEDRLQMDNGMVPCKIVSVHLQETTLKELKQVTPSMKEKSVSITQMNEVTPDTFGTTVKTQLGVSESAGQGDSEAKEEKSKLVKENGDESNSLSDKETGFGEHHHLHLSSCRECLQLENSTIESVRFASAEDIPELPDDCNSKLEENGDCLTTGIKRVNLAGKPPNILIYVGSGTAKVDFEQVKSIIQECVDTDSYTIYQLHEEQVLKAPWIDNSLLLIIATEGPISEKNQKQFMKFLSKGGKILGLSSSFTFDGIQIKRKDKLKRTVHELVVSKMDSTEMKLNLLISGCIFEVAMKEGSSKVKPLSRLNNADKDIVIVYLPYGDNGGEAILSQVHLELDTNSVDIQTEEDFNLLKMSNPKRYEVLKEILISLGLSCELSEIPMLTPIYLLSSDEVLFYFPCPQEIHLTFLKWLEENVNVEGLIESSKVSLKFVSSCESKMEITPSLMSVITKMGNFSSEHFSLETYQQNLQTKKLGKILFFTEVTTTTMNLLDGLMFKLPEEMGLIAIAVRQTQGKGRGGNVWLSPIGCALSTLHITIPLHSNLGQRIPFIQHLVSLAVVESVRSIPGYEDIDLRVKWPNDIYYSDLMKLGGVLVTSTLIETTFHILIGFGFNVNNSNPTICINDLITKFNKEEGTNLKALTADCLIARTVTVLERLIDIFQEKGPNGVLPRYYKYWVHSGKQVRLHNEEGPLAWIVGIDDYGFLQVHEEGKGVESVHPDGNSFDMLKNLIIPKH", "length": 901, "header": "tr|A0A8V0YIG6-1|A0A8V0YIG6_CHICK Isoform 1 of Holocarboxylase synthetase OS=Gallus gallus OX=9031 GN=HLCS PE=3 SV=1 CANONICAL=A0A8V0YIG6-1" }, "locus": { "chromosome": "1", "start_pos": 107069327, "end_pos": 106957069, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031417.1", "url": "https://www.ensembl.org/id/ENSGALT00010031417.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018338.1", "url": "https://www.ensembl.org/id/ENSGALP00010018338.1" } ] } }, { "isoform_ac": "A0A8V0YQA6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIG6/entry#A0A8V0YQA6-1", "sequence": { "sequence": "MLITLCYLYLWARWGPCSAALIRRTVRRLHRSRCSFIFCCSAGPSAPPAHPPRRPAPPEERVCLRIGNKVFFTDETQIVKWSDYCSPLAYKPGEPYKLIAEASVDNFSNLGIAFMEDRLQMDNGMVPCKIVSVHLQETTLKELKQVTPSMKEKSVSITQMNEVTPDTFGTTVKTQLGVSESAGQGDSEAKEEKSKLVKENGDESNSLSDKETGFGEHHHLHLSSCRECLQLENSTIESVRFASAEDIPELPDDCNSKLEENGDCLTTGIKRVNLAGKPPNILIYVGSGTAKVDFEQVKSIIQECVDTDSYTIYQLHEEQVLKAPWIDNSLLLIIATEGPISEKNQKQFMKFLSKGGKILGLSSSFTFDGIQIKRKDKLKRTVHELVVSKMDSTEMKLNLLISGCIFEVAMKEGSSKVKPLSRLNNADKDIVIVYLPYGDNGGEAILSQVHLELDTNSVDIQTEEDFNLLKMSNPKRYEVLKEILISLGLSCELSEIPMLTPIYLLSSDEEIHLTFLKWLEENVNVEGLIESSKVSLKFVSSCESKMEITPSLMSVITKMGNFSSEHFSLETYQQNLQTKKLGKILFFTEVTTTTMNLLDGLMFKLPEEMGLIAIAVRQTQGKGRGGNVWLSPIGCALSTLHITIPLHSNLGQRIPFIQHLVSLAVVESVRSIPGYEDIDLRVKWPNDIYYSDLMKLGGVLVTSTLIETTFHILIGFGFNVNNSNPTICINDLITKFNKEEGTNLKALTADCLIARTVTVLERLIDIFQEKGPNGVLPRYYKYWVHSGKQVRLHNEEGPLAWIVGIDDYGFLQVHEEGKGVESVHPDGNSFDMLKNLIIPKH", "length": 841, "header": "tr|A0A8V0YQA6-1|A0A8V0YQA6_CHICK Computationally mapped isoform of Holocarboxylase synthetase OS=Gallus gallus OX=9031 GN=HLCS PE=3 SV=1 CANONICAL=A0A8V0YIG6-1" }, "locus": { "chromosome": "1", "start_pos": 107069327, "end_pos": 106957069, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031415.1", "url": "https://www.ensembl.org/id/ENSGALT00010031415.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018337.1", "url": "https://www.ensembl.org/id/ENSGALP00010018337.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-196780", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-196780", "resource": "Reactome", "description": "Biotin transport and metabolism" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIG6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIG6" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIG6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIG6" } ], "pmid": "" }, { "name": "nuclear matrix", "id": "GO:0016363", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016363", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIG6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIG6" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIG6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIG6" } ], "pmid": "" }, { "name": "nuclear lamina", "id": "GO:0005652", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005652", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIG6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIG6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "enzyme binding", "id": "GO:0019899", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019899", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIG6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIG6" } ], "pmid": "" }, { "name": "biotin binding", "id": "GO:0009374", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009374", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIG6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIG6" } ], "pmid": "" }, { "name": "biotin--[biotin carboxyl-carrier protein] ligase activity", "id": "GO:0004077", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004077", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIG6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIG6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "post-translational protein modification", "id": "GO:0043687", "url": 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"start_pos": 107093810, "end_pos": 107090639, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031433.1", "url": "https://www.ensembl.org/id/ENSGALT00010031433.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018349.1", "url": "https://www.ensembl.org/id/ENSGALP00010018349.1" } ] } }, { "isoform_ac": "A0A8V0YII3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YII3/entry#A0A8V0YII3-1", "sequence": { "sequence": "MRSLPRPLSVTAHARRRPGRLAISRREGAVSMVENSPAPLPERAIYGFALFLGSWFGFMLYLIWAYVPETWLFSLGLTYWPQKYWAVALPAYLLVAVGIGYVLLFGINMMSTAPLNSTHTITDNYAKKQQQKKFQEEAIPALRDIPISEVNRMFFLPEKGICNSR", "length": 165, "header": "tr|A0A8V0YII3-1|A0A8V0YII3_CHICK Isoform 1 of Phosphatidylinositol glycan anchor biosynthesis class P OS=Gallus gallus OX=9031 GN=PIGP PE=4 SV=1 CANONICAL=A0A8V0YII3-1" }, "locus": { "chromosome": "1", "start_pos": 107094286, "end_pos": 107090639, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031445.1", "url": "https://www.ensembl.org/id/ENSGALT00010031445.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018359.1", "url": "https://www.ensembl.org/id/ENSGALP00010018359.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-162710", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-162710", "resource": "Reactome", "description": "Synthesis of glycosylphosphatidylinositol (GPI)" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YII3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YII3" } ], "pmid": "" }, { "name": "glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex", "id": "GO:0000506", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000506", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YII3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YII3" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YII3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YII3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "GPI anchor biosynthetic process", "id": "GO:0006506", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006506", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YII3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YII3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "phosphatidylinositol N-acetylglucosaminyltransferase activity", "id": "GO:0017176", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017176", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YII3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YII3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 116, "end_pos": 118, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YII3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YII3" }, { "id": "PF08510", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08510" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PIG-P", "eco_id": "ECO_0000259", "start_pos": 43, "end_pos": 155, "start_aa": "Arg", "end_aa": "Phe", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 116, "end_pos": 118 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YIH8-1", "uniprot_ac": "A0A8V0YIH8", "uniprot_id": "A0A8V0YIH8_CHICK", "mass": { "chemical_mass": 92008.0, "monoisotopic_mass": 92008.0 }, "refseq": {}, "gene_names": [ { "name": "APBA1", "type": "recommended", "evidence": [ { "id": "A0A8V0YIH8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIH8" } ] } ], "protein_names": [ { "name": "Amyloid beta protein binding family A member 1", "type": "synonym", "evidence": [ { "id": "A0A8V0YIH8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIH8/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIH8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIH8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "APBA1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIH8", "locus": { "chromosome": "Z", "start_pos": 35312132, "end_pos": 35392994, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010014837", "url": "https://www.ensembl.org/id/ENSGALG00010014837" } ] } } ], "crossref": [ { "id": "A0A8V0YIH8", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YIH8", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd01208", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01208", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd06720", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06720", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd06793", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06793", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd22578", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22578", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001478", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001478", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006020", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006020", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036034", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036034", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051230", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051230", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YIH8", "url": "https://www.orthodb.org/?gene=A0A8V0YIH8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YPY1", "url": "https://www.orthodb.org/?gene=A0A8V0YPY1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12345", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12345", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12345:SF14", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12345:SF14", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00595", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00595", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00640", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00640", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-212676", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-212676", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YIH8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIH8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YIH8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIH8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YPY1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPY1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YPY1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPY1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNHLVGPPDGEVSEEPANGAVNESVEADLEHSEVEEEQRYASHYPRHTNSSQGGLSGQEEEGMLARSASTESGFHNHTDTAEGDVIATVEDSYDTERVQENEDESAYAVQYRPESEEYTENAEAEHGEAIHNRTLPNHLHFHSIEHEEAMNAAYSGYVYTHRLFHRGEDEQYAEPYADYGLQEHVYEEIGDTPDLDAREGIQLYEREREEADNYRKEALGARLHHYDERSDGESDSPEKEAEFAPYPRMDSYEQEEDIDQIVAEVKQSMSSQSLDKAAEDMPEAEQSLEHAHALAGGGHESNNSQLPPGSRVTSSSGETVQRYSKEKRDAISLAIKDIKEAIEEVKTRTIRSPYTPDEPKEPIWVMRQDISPTRDSDDQRPLDGDSPSPDSSSPRGAESSSRQHHQDVCSTAEPSTKKESRKSLASFPTYVEVPGPCDPEDLIDGIIFAANYLGSTQLLSDKTPSKNVRMMQAQEAVSRIKQMAQKLAKSRKKAPEGESQPMTEVDLFISTQRIKVLNADTQETMMDHPLRTISYIADIGNIVVLMARRRMPRSNSQDNVEASHPSQDGKRQYKMICHVFESEDAQLIAQSIGQAFSVAYQEFLRANGINPEDLSQKEYSDLLNTQDMYNDDLIHFSKSENCKDVYIEKQKGEILGVVIVESGWGSILPTVIIANMMHGGPAEKSGKLNIGDQIMSINGTSLVGLPLSTCQSIIKGLKNQARVKLNIVRCPPVTTVLIRRPDLRYQLGFSVQNGIICSLMRGGIAERGGVRVGHRIIEINGQSVVATPHEKIVHILSNAVGEIHMKTMPAAMYRLLTAQEQPVYI", "length": 825, "header": "tr|A0A8V0YIH8-1|A0A8V0YIH8_CHICK Isoform 1 of Amyloid beta protein binding family A member 1 OS=Gallus gallus OX=9031 GN=APBA1 PE=4 SV=1 CANONICAL=A0A8V0YIH8-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YIH8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIH8/entry#A0A8V0YIH8-1", "sequence": { "sequence": "MNHLVGPPDGEVSEEPANGAVNESVEADLEHSEVEEEQRYASHYPRHTNSSQGGLSGQEEEGMLARSASTESGFHNHTDTAEGDVIATVEDSYDTERVQENEDESAYAVQYRPESEEYTENAEAEHGEAIHNRTLPNHLHFHSIEHEEAMNAAYSGYVYTHRLFHRGEDEQYAEPYADYGLQEHVYEEIGDTPDLDAREGIQLYEREREEADNYRKEALGARLHHYDERSDGESDSPEKEAEFAPYPRMDSYEQEEDIDQIVAEVKQSMSSQSLDKAAEDMPEAEQSLEHAHALAGGGHESNNSQLPPGSRVTSSSGETVQRYSKEKRDAISLAIKDIKEAIEEVKTRTIRSPYTPDEPKEPIWVMRQDISPTRDSDDQRPLDGDSPSPDSSSPRGAESSSRQHHQDVCSTAEPSTKKESRKSLASFPTYVEVPGPCDPEDLIDGIIFAANYLGSTQLLSDKTPSKNVRMMQAQEAVSRIKQMAQKLAKSRKKAPEGESQPMTEVDLFISTQRIKVLNADTQETMMDHPLRTISYIADIGNIVVLMARRRMPRSNSQDNVEASHPSQDGKRQYKMICHVFESEDAQLIAQSIGQAFSVAYQEFLRANGINPEDLSQKEYSDLLNTQDMYNDDLIHFSKSENCKDVYIEKQKGEILGVVIVESGWGSILPTVIIANMMHGGPAEKSGKLNIGDQIMSINGTSLVGLPLSTCQSIIKGLKNQARVKLNIVRCPPVTTVLIRRPDLRYQLGFSVQNGIICSLMRGGIAERGGVRVGHRIIEINGQSVVATPHEKIVHILSNAVGEIHMKTMPAAMYRLLTAQEQPVYI", "length": 825, "header": "tr|A0A8V0YIH8-1|A0A8V0YIH8_CHICK Isoform 1 of Amyloid beta protein binding family A member 1 OS=Gallus gallus OX=9031 GN=APBA1 PE=4 SV=1 CANONICAL=A0A8V0YIH8-1" }, "locus": { "chromosome": "Z", "start_pos": 35347771, "end_pos": 35315325, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010035705.1", "url": "https://www.ensembl.org/id/ENSGALT00010035705.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020715.1", "url": "https://www.ensembl.org/id/ENSGALP00010020715.1" } ] } }, { "isoform_ac": "A0A8V0YPY1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIH8/entry#A0A8V0YPY1-1", "sequence": { "sequence": 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"https://www.ebi.ac.uk/interpro/entry/IPR036427", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YII6", "url": "https://www.orthodb.org/?gene=A0A8V0YII6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45915", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45915", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45915:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45915:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00439", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00439", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00628", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00628", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00643", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00643", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YII6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YII6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YII6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YII6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": 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"tr|A0A8V0YII6-1|A0A8V0YII6_CHICK Isoform 1 of RING-type E3 ubiquitin transferase OS=Gallus gallus OX=9031 GN=TRIM24 PE=4 SV=1 CANONICAL=A0A8V0YII6-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YII6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YII6/entry#A0A8V0YII6-1", "sequence": { "sequence": 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"tr|A0A8V0YII6-1|A0A8V0YII6_CHICK Isoform 1 of RING-type E3 ubiquitin transferase OS=Gallus gallus OX=9031 GN=TRIM24 PE=4 SV=1 CANONICAL=A0A8V0YII6-1" }, "locus": { "chromosome": "1", "start_pos": 56481653, "end_pos": 56424675, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031830.1", "url": "https://www.ensembl.org/id/ENSGALT00010031830.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018636.1", "url": "https://www.ensembl.org/id/ENSGALP00010018636.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 491, "start_aa": "Thr", "end_pos": 491, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr491", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 831, "start_aa": "Thr", "end_pos": 831, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr831", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "perichromatin fibrils", "id": "GO:0005726", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005726", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YII6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YII6" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YII6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YII6" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YII6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YII6" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YII6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YII6" } ], "pmid": "" }, { "name": "euchromatin", "id": "GO:0000791", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000791", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YII6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YII6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 9, "go_terms": [ { "name": "estrogen response element binding", "id": "GO:0034056", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034056", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YII6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YII6" } ], "pmid": "" }, { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YII6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YII6" } ], "pmid": "" }, { "name": "transcription coactivator activity", "id": "GO:0003713", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003713", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YII6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YII6" } ], "pmid": "" }, { "name": "protein kinase activity", "id": "GO:0004672", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004672", 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"database": "UniProtKB", "id": "A0A8V0YII6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YII6" } ], "pmid": "" }, { "name": "histone H3K23ac reader activity", "id": "GO:0140118", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140118", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YII6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YII6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YII6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YII6" } ], "pmid": "" }, { "name": "regulation of protein stability", "id": "GO:0031647", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031647", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YII6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YII6" } ], "pmid": "" }, { "name": "protein ubiquitination", "id": "GO:0016567", 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"end_pos": 569 }, { "start_pos": 657, "end_pos": 659 }, { "start_pos": 673, "end_pos": 675 }, { "start_pos": 701, "end_pos": 703 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", 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"field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YF25-1", "uniprot_ac": "A0A8V0YF25", "uniprot_id": "A0A8V0YF25_CHICK", "mass": { "chemical_mass": 132010.0, "monoisotopic_mass": 132010.0 }, "refseq": {}, "gene_names": [ { "name": "PKP4", "type": "recommended", "evidence": [ { "id": "A0A8V0YF25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF25" } ] } ], "protein_names": [ { "name": "Plakophilin 4", "type": "synonym", "evidence": [ { "id": "A0A8V0YF25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF25/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YF25", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF25" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PKP4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF25", "locus": { "chromosome": "7", "start_pos": 36047271, "end_pos": 35980036, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010010824", "url": "https://www.ensembl.org/id/ENSGALG00010010824" } ] } } ], "crossref": [ { "id": "A0A8V0YF25", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YF25", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR000225", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000225", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028435", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028435", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y1Y0", "url": "https://www.orthodb.org/?gene=A0A8V0Y1Y0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y838", "url": "https://www.orthodb.org/?gene=A0A8V0Y838", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YF15", "url": "https://www.orthodb.org/?gene=A0A8V0YF15", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YF25", "url": "https://www.orthodb.org/?gene=A0A8V0YF25", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10372", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10372", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10372:SF8", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10372:SF8", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00514", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00514", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-6805567", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6805567", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-6809371", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6809371", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9696264", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9696264", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9696270", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9696270", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0Y1Y0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y1Y0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y1Y0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y1Y0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y838", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y838", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y838-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y838-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YF15", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF15", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YF15-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF15-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YF25", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF25", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YF25-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF25-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPAPEQTPVVEEGLLQATQETSTSPGMEPETTATTILASVKEQELQFQRLTRELEVERQIVANQLERCRLGAESPSIASTSSTEKSFPWRSPDPAATSANKPLVSEGVHTNAYHIRTEPVQGNLYSPEQTSLHERSVGNSRSSTQMNSYSDSGYQEVSSFHNSQNLNKPESRQQHSRIGTATNHLVRSSRAEGQTLVQPSANVATNRAMRRVSSVPSRAQSPSYVVSTGVSPSRGSLRTSLGSGYGSPSVAEQRSLASHAYSSTTLPVQRAASPYAAQRPASPVTVRRIGSITSRQTANPNGGTSQYQASARVGSPLALTDVQTRVVSPPQTQLGSSSPKRSGMTAVPQHLGTTLQRTVHDIEQYGQQYDIYERMVPPRPDSLTGLRSSYASQHSQLGQELRSAVSPDLHITPIYEGRTYYSPVYRSPNHGTIELHQGSQSALYRTGSGVGNLQRSSSQRSTLTYQRNNYALNTTATYAEPYRSMQYRLSESGYNRLQHTAPADDGTTRSPSIDSIQKDPRQFAWRDPELPEVIHMLQHQFPSVQANAAAYLQHLCFGDNKVKTEVCRLGGIKHLVDLLDHRALEVQKNACGALRNLVYGKSTDENKIAMKNVGGIPALLRLLRKSVDAEIKELVTGVLWNLSSCDAVKMTIIRDALSTLTNTVIVPHSGWNSASFDDDHKIKFQTSLVLRNTTGCLRNLSSAGEEARKQMRSCEGLVDSLLYVIHTCVNTSDYDSKTVENCVCTLRNLSYRLELEVPQARLLGINELDDLLGKESPSKDSEPSCWGKKKKKKKKTSQEDQWDGVGPIPGFSKSPKGVEMLWHPSVVKPYLTLLAESSNPATLEGSAGSLQNLSAGNWKFAAYIRAAVRKEKGLPILVELLRMDNDRVVSSVATALRNMALDVRNKELIGKYAMRDLVNRLPGGNGPSILSDETVAAICCALHEVTSKNMENAKALADTGGIEKLVNITKGRGDRSSLKVVKAAAQVLNTLWQYRDLRSIYKKDGWNQSHFITPVSTLERERFKSHPSLSTANQQMSPVIQSVGSTSSSPALLGIREPRSEYDRTQPSMQYYNNHGDIITHKDIYTGSSKTSPIYISSYSSPAREQNRRLQHQQLYYSQEDTNRKNCDAYRLYLQSPHSYEDPYFDDRVHFPASSDYTTQYGLKSTTNYVDFYSTRRSSYRAEQYPGSPDSWV", "length": 1193, "header": "tr|A0A8V0YF25-1|A0A8V0YF25_CHICK Isoform 1 of Plakophilin 4 OS=Gallus gallus OX=9031 GN=PKP4 PE=1 SV=1 CANONICAL=A0A8V0YF25-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Y1Y0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF25/entry#A0A8V0Y1Y0-1", "sequence": { "sequence": "MPAPEQTPVVEEGLLQATQETSTSPGMEPETTATTILASVKEQELQFQRLTRELEVERQIVANQLERCRLGAESPSIASTSSTEKSFPWRSPDPAATSANKPLVSEGVHTNAYHIRTEPVQGNLYSPEQTSLHESEGLYERNKEQRSVGNSRSSTQMNSYSDSGYQEVSSFHNSQNLNKPESRQQHSRIGTATNHLVRSSRAEGQTLVQPSANVATNRAMRRVSSVPSRAQSPSYVVSTGVSPSRGSLRTSLGSGYGSPSVAEQRSLASHAYSSTTLPVQRAASPYAAQRPASPVTVRRIGSITSRQTANPNGGTSQYQASARVGSPLALTDVQTRVVSPPQTQLGSSSPKRSGMTAVPQHLGTTLQRTVHDIEQYGQQYDIYERMVPPRPDSLTGLRSSYASQHSQLGQELRSAVSPDLHITPIYEGRTYYSPVYRSPNHGTIELHQGSQSALYRTGSGVGNLQRSSSQRSTLTYQRNNYALNTTATYAEPYRSMQYRLSESGYNRLQHTAPADDGTTRSPSIDSIQKDPRQFAWRDPELPEVIHMLQHQFPSVQANAAAYLQHLCFGDNKVKTEVCRLGGIKHLVDLLDHRALEVQKNACGALRNLVYGKSTDENKIAMKNVGGIPALLRLLRKSVDAEIKELVTGVLWNLSSCDAVKMTIIRDALSTLTNTVIVPHSGWNSASFDDDHKIKFQTSLVLRNTTGCLRNLSSAGEEARKQMRSCEGLVDSLLYVIHTCVNTSDYDSKTVENCVCTLRNLSYRLELEVPQARLLGINELDDLLGKESPSKDSEPSCWGKKKKKKKKTSQEDQWDGVGPIPGFSKSPKGVEMLWHPSVVKPYLTLLAESSNPATLEGSAGSLQNLSAGNWKFAAYIRAAVRKEKGLPILVELLRMDNDRVVSSVATALRNMALDVRNKELIGKYAMRDLVNRLPGGNGPSILSDETVAAICCALHEVTSKNMENAKALADTGGIEKLVNITKGRGDRSSLKVVKAAAQVLNTLWQYRDLRSIYKKDGWNQSHFITPVSTLERERFKSHPSLSTANQQMSPVIQSVGSTSSSPALLGIREPRSEYDRTQPSMQYYNNHGDIITHKDIYTGSSKTSPIYISSYSSPAREQNRRLQHQQLYYSQEDTNRKNCDAYRLYLQSPHSYEDPYFDDRVHFPASSDYTTQYGLKSTTNYVDFYSTRRSSYRAEQYPGSPDSWV", "length": 1204, "header": "tr|A0A8V0Y1Y0-1|A0A8V0Y1Y0_CHICK Computationally mapped isoform of Plakophilin 4 OS=Gallus gallus OX=9031 GN=PKP4 PE=1 SV=1 CANONICAL=A0A8V0YF25-1" }, "locus": { "chromosome": "7", "start_pos": 36046465, "end_pos": 35999028, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010025909.1", "url": "https://www.ensembl.org/id/ENSGALT00010025909.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010014584.1", "url": "https://www.ensembl.org/id/ENSGALP00010014584.1" } ] } }, { "isoform_ac": "A0A8V0Y838-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF25/entry#A0A8V0Y838-1", "sequence": { "sequence": "MSTDPAATSANKPLVSEGVHTNAYHIRTEPVQGNLYSPEQTSLHESEGSVGNSRSSTQMNSYSDSGYQEVSSFHNSQNLNKPESRQQHSRIGTATNHLVRSSRAEGQTLVQPSANVATNRAMRRVSSVPSRAQSPSYVVSTGVSPSRGSLRTSLGSGYGSPSVAEQRSLASHAYSSTTLPVQRAASPYAAQRPASPVTVRRIGSITSRQTANPNGGTSQYQASARVGSPLALTDVQTRVVSPPQTQLGSSSPKRSGMTAVPQHLGTTLQRTVHDIEQYGQQYDIYERMVPPRPDSLTGLRSSYASQHSQLGQELRSAVSPDLHITPIYEGRTYYSPVYRSPNHGTIELHQGSQSALYRTGSGVGNLQRSSSQRSTLTYQRNNYALNTTATYAEPYRSMQYRLSESGYNRLQHTAPADDGTTRSPSIDSIQKDPRQFAWRDPELPEVIHMLQHQFPSVQANAAAYLQHLCFGDNKVKTEVCRLGGIKHLVDLLDHRALEVQKNACGALRNLVYGKSTDENKIAMKNVGGIPALLRLLRKSVDAEIKELVTGVLWNLSSCDAVKMTIIRDALSTLTNTVIVPHSGWNSASFDDDHKIKFQTSLVLRNTTGCLRNLSSAGEEARKQMRSCEGLVDSLLYVIHTCVNTSDYDSKTVENCVCTLRNLSYRLELEVPQARLLGINELDDLLGKESPSKDSEPSCWGKKKKKKKKTSQEDQWDGVGPIPGFSKSPKGVEMLWHPSVVKPYLTLLAESSNPATLEGSAGSLQNLSAGNWKFAAYIRAAVRKEKGLPILVELLRMDNDRVVSSVATALRNMALDVRNKELIGKYAMRDLVNRLPGGNGPSILSDETVAAICCALHEVTSKNMENAKALADTGGIEKLVNITKGRGDRSSLKVVKAAAQVLNTLWQYRDLRSIYKKDGWNQSHFITPVSTLERERFKSHPSLSTANQQMSPVIQSVGSTSSSPALLGIREPRSEYDRTQPSMQYYNNHGDIITHKDIYTGSSKTSPIYISSYSSPAREQNRRLQHQQLYYSQEDTNRKNCDAYRLYLQSPHSYEDPYFDDRVHFPASSDYTTQYGLKSTTNYVDFYSTRRSSYRAEQYPGSPDSWV", "length": 1106, "header": "tr|A0A8V0Y838-1|A0A8V0Y838_CHICK Computationally mapped isoform of Plakophilin 4 OS=Gallus gallus OX=9031 GN=PKP4 PE=1 SV=1 CANONICAL=A0A8V0YF25-1" }, "locus": { "chromosome": "7", "start_pos": 36046465, "end_pos": 36018457, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010025892.1", "url": "https://www.ensembl.org/id/ENSGALT00010025892.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010014571.1", "url": "https://www.ensembl.org/id/ENSGALP00010014571.1" } ] } }, { "isoform_ac": "A0A8V0YF15-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF25/entry#A0A8V0YF15-1", "sequence": { "sequence": "MEVWPKGEMPAPEQTPVVEEGLLQATQETSTSPGMEPETTATTILASVKEQELQFQRLTRELEVERQIVANQLERCRLGAESPSIASTSSTEKSFPWRSPDPAATSANKPLVSEGVHTNAYHIRTEPVQGNLYSPEQTSLHESEGSVGNSRSSTQMNSYSDSGYQEVSSFHNSQNLNKPESRQQHSRIGTATNHLVRSSRAEGQTLVQPSANVATNRAMRRVSSVPSRAQSPSYVVSTGVSPSRGSLRTSLGSGYGSPSVAEQRSLASHAYSSTTLPVQRAASPYAAQRPASPVTVRRIGSITSRQTANPNGGTSQYQASARVGSPLALTDVQTRVVSPPQTQLGSSSPKRSGMTAVPQHLGTTLQRTVHDIEQYGQQYDIYERMVPPRPDSLTGLRSSYASQHSQLGQELRSAVSPDLHITPIYEGRTYYSPVYRSPNHGTIELHQGSQSALYRTGSGVGNLQRSSSQRSTLTYQRNNYALNTTATYAEPYRSMQYRLSESGYNRLQHTAPADDGTTRSPSIDSIQKDPRQFAWRDPELPEVIHMLQHQFPSVQANAAAYLQHLCFGDNKVKTEVCRLGGIKHLVDLLDHRALEVQKNACGALRNLVYGKSTDENKIAMKNVGGIPALLRLLRKSVDAEIKELVTGVLWNLSSCDAVKMTIIRDALSTLTNTVIVPHSGWNSASFDDDHKIKFQTSLVLRNTTGCLRNLSSAGEEARKQMRSCEGLVDSLLYVIHTCVNTSDYDSKTVENCVCTLRNLSYRLELEVPQARLLGINELDDLLGKESPSKDSEPSCWGKKKKKKKKTSQEDQWDGVGPIPGFSKSPKGVEMLWHPSVVKPYLTLLAESSNPATLEGSAGSLQNLSAGNWKFAAYIRAAVRKEKGLPILVELLRMDNDRVVSSVATALRNMALDVRNKELIGKYAMRDLVNRLPGGNGPSILSDETVAAICCALHEVTSKNMENAKALADTGGIEKLVNITKGRGDRSSLKVVKAAAQVLNTLWQYRDLRSIYKKDGWNQSHFITPVSTLERERFKSHPSLSTANQQMSPVIQSVGSTSSSPALLGIREPRSEYDRTQPSMQYYNNHGDIITHKDIYTGSSKTSPIYISSYSSPAREQNRRLQHQQLYYSQEDTNRKNCDAYRLYLQSPHSYEDPYFDDRVHFPASSDYTTQYGLKSTTNYVDFYSTRRSSYRAEQYPGSPDSWV", "length": 1203, "header": "tr|A0A8V0YF15-1|A0A8V0YF15_CHICK Computationally mapped isoform of Plakophilin 4 OS=Gallus gallus OX=9031 GN=PKP4 PE=1 SV=1 CANONICAL=A0A8V0YF25-1" }, "locus": { "chromosome": "7", "start_pos": 36046465, "end_pos": 35980446, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010025896.1", "url": "https://www.ensembl.org/id/ENSGALT00010025896.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010014575.1", "url": "https://www.ensembl.org/id/ENSGALP00010014575.1" } ] } }, { "isoform_ac": "A0A8V0YF25-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF25/entry#A0A8V0YF25-1", "sequence": { "sequence": "MPAPEQTPVVEEGLLQATQETSTSPGMEPETTATTILASVKEQELQFQRLTRELEVERQIVANQLERCRLGAESPSIASTSSTEKSFPWRSPDPAATSANKPLVSEGVHTNAYHIRTEPVQGNLYSPEQTSLHERSVGNSRSSTQMNSYSDSGYQEVSSFHNSQNLNKPESRQQHSRIGTATNHLVRSSRAEGQTLVQPSANVATNRAMRRVSSVPSRAQSPSYVVSTGVSPSRGSLRTSLGSGYGSPSVAEQRSLASHAYSSTTLPVQRAASPYAAQRPASPVTVRRIGSITSRQTANPNGGTSQYQASARVGSPLALTDVQTRVVSPPQTQLGSSSPKRSGMTAVPQHLGTTLQRTVHDIEQYGQQYDIYERMVPPRPDSLTGLRSSYASQHSQLGQELRSAVSPDLHITPIYEGRTYYSPVYRSPNHGTIELHQGSQSALYRTGSGVGNLQRSSSQRSTLTYQRNNYALNTTATYAEPYRSMQYRLSESGYNRLQHTAPADDGTTRSPSIDSIQKDPRQFAWRDPELPEVIHMLQHQFPSVQANAAAYLQHLCFGDNKVKTEVCRLGGIKHLVDLLDHRALEVQKNACGALRNLVYGKSTDENKIAMKNVGGIPALLRLLRKSVDAEIKELVTGVLWNLSSCDAVKMTIIRDALSTLTNTVIVPHSGWNSASFDDDHKIKFQTSLVLRNTTGCLRNLSSAGEEARKQMRSCEGLVDSLLYVIHTCVNTSDYDSKTVENCVCTLRNLSYRLELEVPQARLLGINELDDLLGKESPSKDSEPSCWGKKKKKKKKTSQEDQWDGVGPIPGFSKSPKGVEMLWHPSVVKPYLTLLAESSNPATLEGSAGSLQNLSAGNWKFAAYIRAAVRKEKGLPILVELLRMDNDRVVSSVATALRNMALDVRNKELIGKYAMRDLVNRLPGGNGPSILSDETVAAICCALHEVTSKNMENAKALADTGGIEKLVNITKGRGDRSSLKVVKAAAQVLNTLWQYRDLRSIYKKDGWNQSHFITPVSTLERERFKSHPSLSTANQQMSPVIQSVGSTSSSPALLGIREPRSEYDRTQPSMQYYNNHGDIITHKDIYTGSSKTSPIYISSYSSPAREQNRRLQHQQLYYSQEDTNRKNCDAYRLYLQSPHSYEDPYFDDRVHFPASSDYTTQYGLKSTTNYVDFYSTRRSSYRAEQYPGSPDSWV", 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This record is derived from a genomic sequence (NC_052575.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_046770235", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046770235" } ] }, { "annotation": "Binds directly to 5'-TTAGGG-3' repeats in telomeric DNA. Associates with the telomerase complex at sites of active telomere processing and positively regulates telomere elongation. Important for TERT binding to chromatin, indicating a role in recruitment of the telomerase complex to telomeres. Also plays a role in the alternative lengthening of telomeres (ALT) pathway in telomerase-negative cells where it promotes formation and/or maintenance of ALT-associated promyelocytic leukemia bodies (APBs). Enhances formation of telomere C-circles in ALT cells, suggesting a possible role in telomere recombination. 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"database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000016633", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000016633", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00086", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00086", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd00093", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00093", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "422024", "url": "https://www.ncbi.nlm.nih.gov/gene/422024", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001356", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001356", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001387", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001387", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006899", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006899", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009057", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009057", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR010982", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010982", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040363", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040363", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044866", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044866", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044869", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044869", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:422024", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422024", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "XAAILES", "url": "https://omabrowser.org/oma/group/XAAILES/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y356", "url": "https://www.orthodb.org/?gene=A0A8V0Y356", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y7V0", "url": "https://www.orthodb.org/?gene=A0A8V0Y7V0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y7W4", "url": "https://www.orthodb.org/?gene=A0A8V0Y7W4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y9D8", "url": "https://www.orthodb.org/?gene=A0A8V0Y9D8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y9F0", "url": "https://www.orthodb.org/?gene=A0A8V0Y9F0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YBM2", "url": "https://www.orthodb.org/?gene=A0A8V0YBM2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YGA4", "url": "https://www.orthodb.org/?gene=A0A8V0YGA4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YGB0", "url": "https://www.orthodb.org/?gene=A0A8V0YGB0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YGB9", "url": "https://www.orthodb.org/?gene=A0A8V0YGB9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1BZ53", "url": "https://www.orthodb.org/?gene=E1BZ53", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14618", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14618", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14618:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14618:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00046", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00046", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF04814", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04814", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_046770235", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046770235", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Y356", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y356", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y356-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y356-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y7V0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y7V0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y7V0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y7V0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y7W4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y7W4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y7W4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y7W4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y9D8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9D8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y9D8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9D8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y9F0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9F0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y9F0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9F0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YBM2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBM2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YBM2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBM2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YGA4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGA4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YGA4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGA4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YGB0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGB0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YGB0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGB0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YGB9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGB9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YGB9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGB9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BZ53", "url": "https://www.uniprot.org/uniprotkb/E1BZ53", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BZ53-1", "url": "https://www.uniprot.org/uniprotkb/E1BZ53-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLRTFPVVLLETMSHYTDEPRFTIEQIDLLQRLRRTGMTRHEILHALETLDRLDQEHSDKFGRRSSYGGGSYSNSTNNVPASSSTATASTQTQHSGMSPSPSNSYDTSPQPCTTNQNGRESNERLSAFNGKMSPTRYPLANSLAQRSYSFEASEEDLDIDDKVEELMRRDSSVIKEEIKAFLANRRISQAVVAQVTGISQSRISHWLLQQGSDLSEQKKRAFYRWYQLEKTNPGATLSMRPAPIPIEEPEWRQTPPPVTATSGTFRLRRGSRFTWRKECLAVMESYFNENQYPDEAKREEIANACNAVIQKPGKKLSDLERVTSLKVYNWFANRRKEIKRRANIAILESHGIDVQSPGGHSNSDDVDGNDYSEQDDSTSHSDHQDPISLAVEMAAVNHTILALARQGANEIKTEALDDD", "length": 419, "header": "tr|A0A8V0YGB9-1|A0A8V0YGB9_CHICK Isoform 1 of Homeobox-containing protein 1 OS=Gallus gallus OX=9031 GN=HMBOX1 PE=4 SV=1 CANONICAL=A0A8V0YGB9-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Y356-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGB9/entry#A0A8V0Y356-1", "sequence": { "sequence": "MLRTFPVVLLETMSHYTDEPRFTIEQIDLLQRLRRTGMTRHEILHALETLDRLDQEHSDKFGRRSSYGGGSYSNSTNNVPASSSTATASTQTQHSGMSPSPSNSYDTSPQPCTTNQNGRESNERLSAFNGKMSPTRYPLANSLAQRSYSFEASEEDLDIDDKVEELMRRDSSVIKEEIKAFLANRRISQAVVAQVTGISQSRISHWLLQQGSDLSEQKKRAFYRWYQLEKTNPGATLSMRPAPIPIEEPEWRQTPPPVTATSGTFRLRRGSRFTWRKECLAVMESYFNENQYPDEAKREEIANACNAVIQKPGKKLSDLERVTSLKVYNWFANRRKEIKRRANIGNVSESLLSRFSTLTCSGEIKITRDCITENTGGSDNLNRIVGQFFKKEDLLFRIFSQIQAGI", "length": 406, "header": "tr|A0A8V0Y356-1|A0A8V0Y356_CHICK Computationally mapped isoform of Homeobox-containing protein 1 OS=Gallus gallus OX=9031 GN=HMBOX1 PE=4 SV=1 CANONICAL=A0A8V0YGB9-1" }, "locus": { "chromosome": "3", "start_pos": 105999834, "end_pos": 105942205, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026427.1", "url": "https://www.ensembl.org/id/ENSGALT00010026427.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015039.1", "url": "https://www.ensembl.org/id/ENSGALP00010015039.1" } ] } }, { "isoform_ac": "A0A8V0Y7V0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGB9/entry#A0A8V0Y7V0-1", "sequence": { "sequence": "MLRTFPVVLLETMSHYTDEPRFTIEQIDLLQRLRRTGMTRHEILHALETLDRLDQEHSDKFGRRSSYGGGSYSNSTNNVPASSSTATASTQTQHSGMSPSPSNSYDTSPQPCTTNQNGRESNERLSAFNGKMSPTRYPLANSLAQRSYSFEASEEDLDIDDKVEELMRRDSSVIKEEIKAFLANRRISQAVVAQVTGISQSRISHWLLQQGSDLSEQKKRAFYRWYQLEKTNPGATLSMRPAPIPIEEPEWRQTPPPVTATSGTFRLRRGSRFTWRKECLAVMESYFNENQYPDEAKREEIANACNAVIQKPGKKLSDLERVTSLKVYNWFANRRKEIKRRANIEAAILESHGIDVQSPGGHSNSDDVDGNDYSEQDTWQVRNGEEEGRCSEGGREAEKVEEDRRICSKQASYTIHATRNDDSTSHSDHQDPISLAVEMAAVNHTILALARQGANEIKTEALDDD", "length": 465, "header": "tr|A0A8V0Y7V0-1|A0A8V0Y7V0_CHICK Computationally mapped isoform of Homeobox-containing protein 1 OS=Gallus gallus OX=9031 GN=HMBOX1 PE=4 SV=1 CANONICAL=A0A8V0YGB9-1" }, "locus": { "chromosome": "3", "start_pos": 106005208, "end_pos": 105942205, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026419.1", "url": "https://www.ensembl.org/id/ENSGALT00010026419.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015033.1", "url": "https://www.ensembl.org/id/ENSGALP00010015033.1" } ] } }, { "isoform_ac": "A0A8V0Y7W4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGB9/entry#A0A8V0Y7W4-1", "sequence": { "sequence": "MLRTFPVVLLETMSHYTDEPRFTIEQIDLLQRLRRTGMTRHEILHALETLDRLDQEHSDKFGRRSSYGGGSYSNSTNNVPASSSTATASTQTQHSGMSPSPSNSYDTSPQPCTTNQNGRESNERLSAFNGKMSPTRYPLANSLAQRSYSFEASEEDLDIDDKVEELMRRDSSVIKEEIKAFLANRRISQAVVAQVTGISQSRISHWLLQQGSDLSEQKKRAFYRWYQLEKTNPGATLSMRPAPIPIEEPEWRQTPPPVTATSGTFRLRRGSRFTWRKECLAVMESYFNENQYPDEAKREEIANACNAVIQKPGKKLSDLERVTSLKVYNWFANRRKEIKRRANIEAAILESHGIDVQSPGGHSNSDDVDGNDYSEQDTWQVRNGEEEGRCSEGGREAEKVEEDRRICSKQQKNTPSRTLSPHLP", "length": 424, "header": "tr|A0A8V0Y7W4-1|A0A8V0Y7W4_CHICK Computationally mapped isoform of Homeobox-containing protein 1 OS=Gallus gallus OX=9031 GN=HMBOX1 PE=4 SV=1 CANONICAL=A0A8V0YGB9-1" }, "locus": { "chromosome": "3", "start_pos": 106002457, "end_pos": 105942205, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026436.1", "url": "https://www.ensembl.org/id/ENSGALT00010026436.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015048.1", "url": "https://www.ensembl.org/id/ENSGALP00010015048.1" } ] } }, { "isoform_ac": "A0A8V0Y9D8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGB9/entry#A0A8V0Y9D8-1", "sequence": { "sequence": "MLRTFPVVLLETMSHYTDEPRFTIEQIDLLQRLRRTGMTRHEILHALETLDRLDQEHSDKFGRRSSYGGGSYSNSTNNVPASSSTATASTQTQHSGMSPSPSNSYDTSPQPCTTNQNGRESNERLSAFNGKMSPTRYPLANSLAQRSYSFEASEEDLDIDDKVEELMRRDSSVIKEEIKAFLANRRISQAVVAQVTGISQSRISHWLLQQGSDLSEQKKRAFYRWYQLEKTNPGATLSMRPAPIPIEEPEWRQTPPPVTATSGTFRLRRGSRFTWRKECLAVMESYFNENQYPDEAKREEIANACNAVIQKPGKKLSDLERVTSLKVYNWFANRRKEIKRRANIEAAILESHGIDVQSPGGHSNSDDVDGNDYSEQDTWQVRNGEEEGRCSEGGREAEKVEEDRRICSKQASYTIHATRNQKNTPSRTLSPHLP", "length": 434, "header": "tr|A0A8V0Y9D8-1|A0A8V0Y9D8_CHICK Computationally mapped isoform of Homeobox-containing protein 1 OS=Gallus gallus OX=9031 GN=HMBOX1 PE=4 SV=1 CANONICAL=A0A8V0YGB9-1" }, "locus": { "chromosome": "3", "start_pos": 106002457, "end_pos": 105942205, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026417.1", "url": "https://www.ensembl.org/id/ENSGALT00010026417.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015031.1", "url": "https://www.ensembl.org/id/ENSGALP00010015031.1" } ] } }, { "isoform_ac": "A0A8V0Y9F0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGB9/entry#A0A8V0Y9F0-1", "sequence": { "sequence": "MSHYTDEPRFTIEQIDLLQRLRRTGMTRHEILHALETLDRLDQEHSDKFGRRSSYGGGSYSNSTNNVPASSSTATASTQTQHSGMSPSPSNSYDTSPQPCTTNQNGRESNERLSAFNGKMSPTRYPLANSLAQRSYSFEASEEDLDIDDKVEELMRRDSSVIKEEIKAFLANRRISQAVVAQVTGISQSRISHWLLQQGSDLSEQKKRAFYRWYQLEKTNPGATLSMRPAPIPIEEPEWRQTPPPVTATSGTFRLRRGSRFTWRKECLAVMESYFNENQYPDEAKREEIANACNAVIQKPGKKLSDLERVTSLKVYNWFANRRKEIKRRANIEAAILESHGIDVQSPGGHSNSDDVDGNDYSEQDTWQVRNGEEEGRCSEGGREAEKVEEDRRICSKQQKNTPSRTLSPHLP", "length": 412, "header": "tr|A0A8V0Y9F0-1|A0A8V0Y9F0_CHICK Computationally mapped isoform of Homeobox-containing protein 1 OS=Gallus gallus OX=9031 GN=HMBOX1 PE=4 SV=1 CANONICAL=A0A8V0YGB9-1" }, "locus": { "chromosome": "3", "start_pos": 106002457, "end_pos": 105954531, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026429.1", "url": "https://www.ensembl.org/id/ENSGALT00010026429.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015041.1", "url": "https://www.ensembl.org/id/ENSGALP00010015041.1" } ] } }, { "isoform_ac": "A0A8V0YBM2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGB9/entry#A0A8V0YBM2-1", "sequence": { "sequence": "MLRTFPVVLLETMSHYTDEPRFTIEQIDLLQRLRRTGMTRHEILHALETLDRLDQEHSDKFGRRSSYGGGSYSNSTNNVPASSSTATASTQTQHSGMSPSPSNSYDTSPQPCTTNQNGRESNERLSAFNGKMSPTRYPLANSLAQRSYSFEASEEDLDIDDKVEELMRRDSSVIKEEIKAFLANRRISQAVVAQVTGATLSMRPAPIPIEEPEWRQTPPPVTATSGTFRLRRGSRFTWRKECLAVMESYFNENQYPDEAKREEIANACNAVIQKPGKKLSDLERVTSLKVYNWFANRRKEIKRRANIEAAILESHGIDVQSPGGHSNSDDVDGNDYSEQDTWQVRNGEEEGRCSEGGREAEKVEEDRRICSKQDDSTSHSDHQDPISLAVEMAAVNHTILALARQGANEIKTEALDDD", "length": 418, "header": "tr|A0A8V0YBM2-1|A0A8V0YBM2_CHICK Computationally mapped isoform of Homeobox containing 1 OS=Gallus gallus OX=9031 GN=HMBOX1 PE=4 SV=1 CANONICAL=A0A8V0YGB9-1" }, "locus": { "chromosome": "3", "start_pos": 106005208, "end_pos": 105942205, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026430.1", "url": "https://www.ensembl.org/id/ENSGALT00010026430.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015042.1", "url": "https://www.ensembl.org/id/ENSGALP00010015042.1" } ] } }, { "isoform_ac": "A0A8V0YGA4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGB9/entry#A0A8V0YGA4-1", "sequence": { "sequence": "MLRTFPVVLLETMSHYTDEPRFTIEQIDLLQRLRRTGMTRHEILHALETLDRLDQEHSDKFGRRSSYGGGSYSNSTNNVPASSSTATASTQTQHSGMSPSPSNSYDTSPQPCTTNQNGRESNERLSAFNGKMSPTRYPLANSLAQRSYSFEASEEDLDIDDKVEELMRRDSSVIKEEIKAFLANRRISQAVVAQVTGISQSRISHWLLQQGSDLSEQKKRAFYRWYQLEKTNPGATLSMRPAPIPIEEPEWRQTPPPVTATSGTFRLRRGSRFTWRKECLAVMESYFNENQYPDEAKREEIANACNAVIQKPGKKLSDLERVTSLKVYNWFANRRKEIKRRANIEAAILESHGIDVQSPGGHSNSDDVDGNDYSEQDTWQVRNGEEEGRCSEGGREAEKVEEDRRICSKQASYTIHATRNV", "length": 421, "header": "tr|A0A8V0YGA4-1|A0A8V0YGA4_CHICK Computationally mapped isoform of Homeobox-containing protein 1 OS=Gallus gallus OX=9031 GN=HMBOX1 PE=4 SV=1 CANONICAL=A0A8V0YGB9-1" }, "locus": { "chromosome": "3", "start_pos": 106001775, "end_pos": 105942205, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026416.1", "url": "https://www.ensembl.org/id/ENSGALT00010026416.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015030.1", "url": "https://www.ensembl.org/id/ENSGALP00010015030.1" } ] } }, { "isoform_ac": "A0A8V0YGB0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGB9/entry#A0A8V0YGB0-1", "sequence": { "sequence": "MSHYTDEPRFTIEQIDLLQRLRRTGMTRHEILHALETLDRLDQEHSDKFGRRSSYGGGSYSNSTNNVPASSSTATASTQTQHSGMSPSPSNSYDTSPQPCTTNQNGRESNERLSAFNGKMSPTRYPLANSLAQRSYSFEASEEDLDIDDKVEELMRRDSSVIKEEIKAFLANRRISQAVVAQVTGISQSRISHWLLQQGSDLSEQKKRAFYRWYQLEKTNPGATLSMRPAPIPIEEPEWRQTPPPVTATSGTFRLRRGSRFTWRKECLAVMESYFNENQYPDEAKREEIANACNAVIQKPGKKLSDLERVTSLKVYNWFANRRKEIKRRANIEAAILESHGIDVQSPGGHSNSDDVDGNDYSEQDTWQVRNGEEEGRCSEGGREAEKDDSTSHSDHQDPISLAVEMAAVNHTILALARQGANEIKTEALDDD", "length": 432, "header": "tr|A0A8V0YGB0-1|A0A8V0YGB0_CHICK Computationally mapped isoform of Homeobox-containing protein 1 OS=Gallus gallus OX=9031 GN=HMBOX1 PE=4 SV=1 CANONICAL=A0A8V0YGB9-1" }, "locus": { "chromosome": "3", "start_pos": 106005208, "end_pos": 105954531, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026422.1", "url": "https://www.ensembl.org/id/ENSGALT00010026422.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015035.1", "url": "https://www.ensembl.org/id/ENSGALP00010015035.1" } ] } }, { "isoform_ac": "A0A8V0YGB9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGB9/entry#A0A8V0YGB9-1", "sequence": { "sequence": "MLRTFPVVLLETMSHYTDEPRFTIEQIDLLQRLRRTGMTRHEILHALETLDRLDQEHSDKFGRRSSYGGGSYSNSTNNVPASSSTATASTQTQHSGMSPSPSNSYDTSPQPCTTNQNGRESNERLSAFNGKMSPTRYPLANSLAQRSYSFEASEEDLDIDDKVEELMRRDSSVIKEEIKAFLANRRISQAVVAQVTGISQSRISHWLLQQGSDLSEQKKRAFYRWYQLEKTNPGATLSMRPAPIPIEEPEWRQTPPPVTATSGTFRLRRGSRFTWRKECLAVMESYFNENQYPDEAKREEIANACNAVIQKPGKKLSDLERVTSLKVYNWFANRRKEIKRRANIAILESHGIDVQSPGGHSNSDDVDGNDYSEQDDSTSHSDHQDPISLAVEMAAVNHTILALARQGANEIKTEALDDD", "length": 419, "header": "tr|A0A8V0YGB9-1|A0A8V0YGB9_CHICK Isoform 1 of Homeobox-containing protein 1 OS=Gallus gallus OX=9031 GN=HMBOX1 PE=4 SV=1 CANONICAL=A0A8V0YGB9-1" }, "locus": { "chromosome": "3", "start_pos": 106005208, "end_pos": 105942205, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026433.1", "url": "https://www.ensembl.org/id/ENSGALT00010026433.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015045.1", "url": "https://www.ensembl.org/id/ENSGALP00010015045.1" } ] } }, { "isoform_ac": "E1BZ53-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGB9/entry#E1BZ53-1", "sequence": { "sequence": "MLRTFPVVLLETMSHYTDEPRFTIEQIDLLQRLRRTGMTRHEILHALETLDRLDQEHSDKFGRRSSYGGGSYSNSTNNVPASSSTATASTQTQHSGMSPSPSNSYDTSPQPCTTNQNGRESNERLSAFNGKMSPTRYPLANSLAQRSYSFEASEEDLDIDDKVEELMRRDSSVIKEEIKAFLANRRISQAVVAQVTGISQSRISHWLLQQGSDLSEQKKRAFYRWYQLEKTNPGATLSMRPAPIPIEEPEWRQTPPPVTATSGTFRLRRGSRFTWRKECLAVMESYFNENQYPDEAKREEIANACNAVIQKPGKKLSDLERVTSLKVYNWFANRRKEIKRRANIAAILESHGIDVQSPGGHSNSDDVDGNDYSEQDTWQVRNGEEEGRCSEGGREAEKVEEDRRICSKQDDSTSHSDHQDPISLAVEMAAVNHTILALARQGANEIKTEALDDD", "length": 454, "header": "tr|E1BZ53-1|E1BZ53_CHICK Computationally mapped isoform of Homeobox-containing protein 1 OS=Gallus gallus OX=9031 GN=HMBOX1 PE=4 SV=4 CANONICAL=A0A8V0YGB9-1" }, "locus": { "chromosome": "3", "start_pos": 106005208, "end_pos": 105942205, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026425.1", "url": "https://www.ensembl.org/id/ENSGALT00010026425.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015037.1", "url": "https://www.ensembl.org/id/ENSGALP00010015037.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:422024", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422024", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "F1N4C1-1", "protein_name": "Homeobox-containing protein 1", "gene_name": "HMBOX1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MLSSFPVVLLETMSHYTDEPRFTIEQIDLLQRLRRTGMTKHEILHALETLDRLDQEHSDKFGRRSSYGGSSYGNSTNNVPASSSTATASTQTQHSGMSPSPSNSYDTSPQPCTTNQNGRENNERLSTSNGKMSPTRYHANSMGQRSYSFEASEEDLDVDDKVEELMRRDSSVIKEEIKAFLANRRISQAVVAQVTGISQSRISHWLLQQGSDLSEQKKRAFYRWYQLEKTNPGATLSMRPAPIPIEDPEWRQTPPPVSATSGTFRLRRGSRFTWRKECLAVMESYFNENQYPDEAKREEIANACNAVIQKPGKKLSDLERVTSLKVYNWFANRRKEIKRRANIEAAILESHGIDVQSPGGHSNSDDVDGNDYSEQDDSTSHSDHQDPISLAVEMAAVNHTILALARQGANEIKTEALDDD", "length": 420 }, "evidence": [ { "id": "A0A8V0YGB9", "url": "https://omabrowser.org/oma/group/A0A8V0YGB9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1RJQ0-1", "protein_name": "Homeobox-containing protein 1", "gene_name": "HMBOX1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MLSSFPVVLLETMSHYTDEPRFTIEQIDLLQRLRRTGMTKHEILHALETLDRLDQEHSDKFGRRSSYGGGSYGNNTNNVPASSSTATASTQTQHSGMSPSPSNSYDTSPQPCTTNQNGRENNERLSTSNGKMSPTRYHANSMGQRSYSFEASEEDLDVDDKVEELMRRDSSVIKEEIKAFLANRRISQAVVAQVTGISQSRISHWLLQQGSDLSEQKKRAFYRWYQLEKTNPGATLSMRPAPIPIEDPEWRQTPPPVSATSGTFRLRRGSRFTWRKECLAVMESYFNENQYPDEAKREEIANACNAVIQKPGKKLSDLERVTSLKVYNWFANRRKEIKRRANIEAAILESHGIDVQSPGGHSNSDDVDGNDYSEQDDSTSHSDHQDPISLAVEMAAVNHTILALARQGANEIKTEALDDD", "length": 420 }, "evidence": [ { "id": "A0A8V0YGB9", "url": "https://omabrowser.org/oma/group/A0A8V0YGB9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q6NT76-1", "protein_name": "Homeobox-containing protein 1", "gene_name": "HMBOX1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLSSFPVVLLETMSHYTDEPRFTIEQIDLLQRLRRTGMTKHEILHALETLDRLDQEHSDKFGRRSSYGGSSYGNSTNNVPASSSTATASTQTQHSGMSPSPSNSYDTSPQPCTTNQNGRENNERLSTSNGKMSPTRYHANSMGQRSYSFEASEEDLDVDDKVEELMRRDSSVIKEEIKAFLANRRISQAVVAQVTGISQSRISHWLLQQGSDLSEQKKRAFYRWYQLEKTNPGATLSMRPAPIPIEDPEWRQTPPPVSATSGTFRLRRGSRFTWRKECLAVMESYFNENQYPDEAKREEIANACNAVIQKPGKKLSDLERVTSLKVYNWFANRRKEIKRRANIEAAILESHGIDVQSPGGHSNSDDVDGNDYSEQDDSTSHSDHQDPISLAVEMAAVNHTILALARQGANEIKTEALDDD", "length": 420 }, "evidence": [ { "id": "A0A8V0YGB9", "url": "https://omabrowser.org/oma/group/A0A8V0YGB9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGB9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGB9" } ], "pmid": "" }, { "name": "PML body", "id": "GO:0016605", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016605", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGB9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGB9" } ], "pmid": "" }, { "name": "Cajal body", "id": "GO:0015030", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015030", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGB9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGB9" } ], "pmid": "" }, { "name": "chromosome, telomeric region", "id": "GO:0000781", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000781", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGB9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGB9" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGB9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGB9" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGB9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGB9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGB9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGB9" } ], "pmid": "" }, { "name": "positive regulation of DNA-templated transcription", "id": "GO:0045893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045893", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGB9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGB9" } ], "pmid": "" }, { "name": "telomere maintenance via telomerase", "id": "GO:0007004", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007004", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGB9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGB9" } ], "pmid": "" }, { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGB9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGB9" } ], "pmid": "" }, { "name": "telomere-telomerase complex assembly", "id": "GO:1905324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905324", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGB9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGB9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "protein-containing complex binding", "id": "GO:0044877", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044877", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGB9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGB9" } ], "pmid": "" }, { "name": "double-stranded telomeric DNA binding", "id": "GO:0003691", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003691", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGB9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGB9" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGB9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGB9" } ], "pmid": "" }, { "name": "sequence-specific double-stranded DNA binding", "id": "GO:1990837", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990837", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGB9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGB9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 397, "end_pos": 399, "annotation": "n_glycosylation_sequon" }, { "start_pos": 74, "end_pos": 76, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YGB9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGB9" }, { "id": "PS51937", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51937" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "HNF-p1", "eco_id": "ECO_0000259", "start_pos": 18, "end_pos": 49, "start_aa": "Asp", "end_aa": "Thr", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0YGB9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGB9" }, { "id": "PS50071", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50071" }, { "id": "PRU00108", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00108" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Homeobox", "eco_id": "ECO_0000259", "start_pos": 266, "end_pos": 341, "start_aa": "Arg", "end_aa": "Arg", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0YGB9", "database": "UniProtKB", "url": 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"o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YF11-1", "uniprot_ac": "A0A8V0YF11", "uniprot_id": "A0A8V0YF11_CHICK", "mass": { "chemical_mass": 61107.0, "monoisotopic_mass": 61107.0 }, "refseq": { "ac": "XP_015145829", "name": "netrin-G1 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015145829" }, "gene_names": [ { "name": "NTNG1", "type": "recommended", "evidence": [ { "id": "A0A8V0YF11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF11" } ] }, { "name": "NTNG1", "type": "synonym", "evidence": [ { "id": "XP_015145829", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015145829" } ] } ], "protein_names": [ { "name": "Netrin-G1", "type": "recommended", "evidence": [ { "id": "A0A8V0YF11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF11/entry#names_and_taxonomy" } ] }, { "name": "Laminet-1", "type": "synonym", "evidence": [ { "id": "A0A8V0YF11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF11/entry#names_and_taxonomy" } ] }, { "name": "netrin-G1 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_015145829", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015145829" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052539.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015145829", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015145829" } ] }, { "annotation": "Involved in controlling patterning and neuronal circuit formation at the laminar, cellular, subcellular and synaptic levels. Promotes neurite outgrowth of both axons and dendrites.", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5NW03", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NW03#function" }, { "database": "UniProtKB", "id": "ARBA00055052", "url": "https://www.uniprot.org/uniprotkb/ARBA00055052#function" }, { "database": "UniProtKB", "id": "A0A8V0Y6K5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y6K5#function" }, { "database": "UniProtKB", "id": "A0A8V0YBG8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBG8#function" }, { "database": "UniProtKB", "id": "A0A8V0YCU1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCU1#function" }, { "database": "UniProtKB", "id": "A0A8V0YF11", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF11#function" }, { "database": "UniProtKB", "id": "A0A8V0Y6L4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y6L4#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YF11", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF11" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "NTNG1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF11", "locus": { "chromosome": "8", "start_pos": 976606, "end_pos": 822381, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010011886", "url": "https://www.ensembl.org/id/ENSGALG00010011886" } ] } } ], "crossref": [ { "id": "A0A8V0YF11", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YF11", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000031122", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000031122", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00054", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00054", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd00055", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00055", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "424336", "url": "https://www.ncbi.nlm.nih.gov/gene/424336", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000742", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000742", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002049", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002049", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008211", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008211", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013111", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013111", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050440", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050440", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056863", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056863", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:424336", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424336", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "AHPTELM", "url": "https://omabrowser.org/oma/group/AHPTELM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5NW03", "url": "https://www.orthodb.org/?gene=A0A1D5NW03", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y6K5", "url": "https://www.orthodb.org/?gene=A0A8V0Y6K5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YBG8", "url": "https://www.orthodb.org/?gene=A0A8V0YBG8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YBI0", "url": "https://www.orthodb.org/?gene=A0A8V0YBI0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YF11", "url": "https://www.orthodb.org/?gene=A0A8V0YF11", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YF21", "url": "https://www.orthodb.org/?gene=A0A8V0YF21", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10574", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10574", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10574:SF28", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10574:SF28", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00053", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00053", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00055", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00055", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07974", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07974", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24973", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24973", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015145829", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015145829", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5NW03", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NW03", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5NW03-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NW03-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y6K5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y6K5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y6K5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y6K5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y6L4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y6L4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y6L4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y6L4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YBG8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBG8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YBG8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBG8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YBI0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBI0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YBI0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBI0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YCU1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCU1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YCU1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCU1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YCU6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCU6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YCU6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCU6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YF06", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF06", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YF06-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF06-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YF11", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF11", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YF11-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF11-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YF21", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF21", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YF21-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF21-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MYLSRFLSLHALWVTVSSMMQHYPSVWGHYDVCKTQIYTEEGKVWDYMACQPEARDMIKYVRVTLDPPDITCGDPPETFCAMGNPYMCNNECDASTQELAHPPELMFDLEGRHPSTFWQSTTWKDYPKPLHVNITLSWNKTIELTDNIVITFESGRPDQMILEKSLDYGRTWQPYQYYATDCLDAFHMDPKSVKDLSQHTVLEIICTEEYSTGYMTNSKIIHFEIKDRFAFFAGPRLHNMASLYGQLDTTKKLRDFFTITDLRIRLLRPATGEIYVDEQHLARYFYAISDIRVYGRCKCNLHATGCKEENKRLLCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANICIPSISSIGNCECFGHSNRCSYIELLNTVICVSCKHNTRGQHCELCRLGYFRNASAELDDENVCIDCYCNPFGSVHDRCNDRGFCECKEGASGPKCDKCLPGYIWHSLGCQPNVCDNELLHCQNGGTCINNVRCQCPPAYTGILCEKLKCERDPGGCSQSSAQGAMSHCPLLLLMALLGAAGVHMC", "length": 539, "header": "tr|A0A8V0YF11-1|A0A8V0YF11_CHICK Isoform 1 of Netrin-G1 OS=Gallus gallus OX=9031 GN=NTNG1 PE=4 SV=1 CANONICAL=A0A8V0YF11-1" }, "isoforms": [ { "isoform_ac": "A0A1D5NW03-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF11/entry#A0A1D5NW03-1", "sequence": { "sequence": "MYLSRFLSLHALWVTVSSMMQHYPSVWGHYDVCKTQIYTEEGKVWDYMACQPEARDMIKYVRVTLDPPDITCGDPPETFCAMGNPYMCNNECDASTQELAHPPELMFDLEGRHPSTFWQSTTWKDYPKPLHVNITLSWNKTIELTDNIVITFESGRPDQMILEKSLDYGRTWQPYQYYATDCLDAFHMDPKSVKDLSQHTVLEIICTEEYSTGYMTNSKIIHFEIKDRFAFFAGPRLHNMASLYGQLDTTKKLRDFFTITDLRIRLLRPATGEIYVDEQHLARYFYAISDIRVYGRCKCNLHATGCKEENKRLLCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANICIPSISSIGNCYCNPFGSVHDRCNDRGFCECKEGASGPKCDKCLPGYIWHSLGCQPNVCDNELLHCQNGGTCINNVRCQCPPAYTGILCEKLKCERDPGGCSQSSAQGAMSHCPLLLLMALLGAAGVHMC", "length": 483, "header": "tr|A0A1D5NW03-1|A0A1D5NW03_CHICK Computationally mapped isoform of Netrin-G1 OS=Gallus gallus OX=9031 GN=NTNG1 PE=4 SV=2 CANONICAL=A0A8V0YF11-1" }, "locus": { "chromosome": "8", "start_pos": 975602, "end_pos": 838282, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028424.1", "url": "https://www.ensembl.org/id/ENSGALT00010028424.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016300.1", "url": "https://www.ensembl.org/id/ENSGALP00010016300.1" } ] } }, { "isoform_ac": "A0A8V0Y6K5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF11/entry#A0A8V0Y6K5-1", "sequence": { "sequence": "MYLSRFLSLHALWVTVSSMMQHYPSVWGHYDVCKTQIYTEEGKVWDYMACQPEARDMIKYVRVTLDPPDITCGDPPETFCAMGNPYMCNNECDASTQELAHPPELMFDLEGRHPSTFWQSTTWKDYPKPLHVNITLSWNKTIELTDNIVITFESGRPDQMILEKSLDYGRTWQPYQYYATDCLDAFHMDPKSVKDLSQHTVLEIICTEEYSTGYMTNSKIIHFEIKDRFAFFAGPRLHNMASLYGQLDTTKKLRDFFTITDLRIRLLRPATGEIYVDEQHLARYFYAISDIRVYGRCKCNLHATGCKEENKRLLCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANICIPSISSIGNPPKFDRIWPNISSLEVSKPNQVAPKLSMTTVSSVQVANHKRDCECFGHSNRCSYIELLNTVICVSCKHNTRGQHCELCRLGYFRNASAELDDENVCIDCYCNPFGSVHDRCNDRGFCECKEGASGPKCDKCLPGYIWHSLGCQPNVCDNELLHCQNGGTCINNVRCQCPPAYTGILCEKLKCERDPGGCSQSSAQGAMSHCPLLLLMALLGAAGVHMC", "length": 581, "header": "tr|A0A8V0Y6K5-1|A0A8V0Y6K5_CHICK Computationally mapped isoform of Netrin-G1 OS=Gallus gallus OX=9031 GN=NTNG1 PE=4 SV=1 CANONICAL=A0A8V0YF11-1" }, "locus": { "chromosome": "8", "start_pos": 975602, "end_pos": 838282, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028413.1", "url": "https://www.ensembl.org/id/ENSGALT00010028413.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016291.1", "url": "https://www.ensembl.org/id/ENSGALP00010016291.1" } ] } }, { "isoform_ac": "A0A8V0Y6L4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF11/entry#A0A8V0Y6L4-1", "sequence": { "sequence": "MYLSRFLSLHALWVTVSSMMQHYPSVWGHYDVCKTQIYTEEGKVWDYMACQPEARDMIKYVRVTLDPPDITCGDPPETFCAMGNPYMCNNECDASTQELAHPPELMFDLEGRHPSTFWQSTTWKDYPKPLHVNITLSWNKTIELTDNIVITFESGRPDQMILEKSLDYGRTWQPYQYYATDCLDAFHMDPKSVKDLSQHTVLEIICTEEYSTGYMTNSKIIHFEIKDRFAFFAGPRLHNMASLYGQLDTTKKLRDFFTITDLRIRLLRPATGEIYVDEQHLARYFYAISDIRVYGRCKCNLHATGCKEENKRLLCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANIYCYCNPFGSVHDRCNDRGFCECKEGASGPKCDKCLPGYIWHSLGCQPNVCDNELLHCQNGGTCINNVRCQCPPAYTGILCEKLKCERDPGGCSQSSAQGAMSHCPLLLLMALLGAAGVHMC", "length": 474, "header": "tr|A0A8V0Y6L4-1|A0A8V0Y6L4_CHICK Computationally mapped isoform of Netrin G1 OS=Gallus gallus OX=9031 GN=NTNG1 PE=4 SV=1 CANONICAL=A0A8V0YF11-1" }, "locus": { "chromosome": "8", "start_pos": 975602, "end_pos": 838282, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028427.1", "url": "https://www.ensembl.org/id/ENSGALT00010028427.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016301.1", "url": "https://www.ensembl.org/id/ENSGALP00010016301.1" } ] } }, { "isoform_ac": "A0A8V0YBG8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF11/entry#A0A8V0YBG8-1", "sequence": { "sequence": "MYLSRFLSLHALWVTVSSMMQHYPSVWGHYDVCKTQIYTEEGKVWDYMACQPEARDMIKYVRVTLDPPDITCGDPPETFCAMGNPYMCNNECDASTQELAHPPELMFDLEGRHPSTFWQSTTWKDYPKPLHVNITLSWNKTIELTDNIVITFESGRPDQMILEKSLDYGRTWQPYQYYATDCLDAFHMDPKSVKDLSQHTVLEIICTEEYSTGYMTNSKIIHFEIKDRFAFFAGPRLHNMASLYGQLDTTKKLRDFFTITDLRIRLLRPATGEIYVDEQHLARYFYAISDIRVYGRCKCNLHATGCKEENKRLLCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANICIPSISSIGNPPKFDRIWPNISSLEVSKPNQVAPKLSMTTVSSVQVANHKRDCYCNPFGSVHDRCNDRGFCECKEGASGPKCDKCLPGYIWHSLGCQPNVCDNELLHCQNGGTCINNVRCQCPPAYTGILCEKLKCERDPGGCSQSSAQGAMSHCPLLLLMALLGAAGVHMC", "length": 525, "header": "tr|A0A8V0YBG8-1|A0A8V0YBG8_CHICK Computationally mapped isoform of Netrin-G1 OS=Gallus gallus OX=9031 GN=NTNG1 PE=4 SV=1 CANONICAL=A0A8V0YF11-1" }, "locus": { "chromosome": "8", "start_pos": 975602, "end_pos": 838282, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028417.1", "url": "https://www.ensembl.org/id/ENSGALT00010028417.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016295.1", "url": "https://www.ensembl.org/id/ENSGALP00010016295.1" } ] } }, { "isoform_ac": "A0A8V0YBI0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF11/entry#A0A8V0YBI0-1", "sequence": { "sequence": "MYLSRFLSLHALWVTVSSMMQHYPSVWGHYDVCKTQIYTEEGKVWDYMACQPEARDMIKYVRVTLDPPDITCGDPPETFCAMGNPYMCNNECDASTQELAHPPELMFDLEGRHPSTFWQSTTWKDYPKPLHVNITLSWNKTIELTDNIVITFESGRPDQMILEKSLDYGRTWQPYQYYATDCLDAFHMDPKSVKDLSQHTVLEIICTEEYSTGYMTNSKIIHFEIKDRFAFFAGPRLHNMASLYGQLDTTKKLRDFFTITDLRIRLLRPATGEIYVDEQHLARYFYAISDIRVYGRCKCNLHATGCKEENKRLLCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANICIPSISSIGNPPKFDRIWPNISSLEVSKPNQVAPKLSMTTVSSVQVANHKRANVCDNELLHCQNGGTCINNVRCQCPPAYTGILCEKLKCERDPGGCSQSSAQGAMSHCPLLLLMALLGAAGVHMC", "length": 479, "header": "tr|A0A8V0YBI0-1|A0A8V0YBI0_CHICK Computationally mapped isoform of Netrin G1 OS=Gallus gallus OX=9031 GN=NTNG1 PE=4 SV=1 CANONICAL=A0A8V0YF11-1" }, "locus": { "chromosome": "8", "start_pos": 975602, "end_pos": 838282, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028432.1", "url": "https://www.ensembl.org/id/ENSGALT00010028432.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016305.1", "url": "https://www.ensembl.org/id/ENSGALP00010016305.1" } ] } }, { "isoform_ac": "A0A8V0YCU1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF11/entry#A0A8V0YCU1-1", "sequence": { "sequence": "MYLSRFLSLHALWVTVSSMMQHYPSVWGHYDVCKTQIYTEEGKVWDYMACQPEARDMIKYVRVTLDPPDITCGDPPETFCAMGNPYMCNNECDASTQELAHPPELMFDLEGRHPSTFWQSTTWKDYPKPLHVNITLSWNKTIELTDNIVITFESGRPDQMILEKSLDYGRTWQPYQYYATDCLDAFHMDPKSVKDLSQHTVLEIICTEEYSTGYMTNSKIIHFEIKDRFAFFAGPRLHNMASLYGQLDTTKKLRDFFTITDLRIRLLRPATGEIYVDEQHLARYFYAISDIRVYGRCKCNLHATGCKEENKRLLCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANICIPSISSIGNPPKFDRIWPNISSLEVSKPNQDCYCNPFGSVHDRCNDRGFCECKEGASGPKCDKCLPGYIWHSLGCQPNVCDNELLHCQNGGTCINNVRCQCPPAYTGILCEKLKCERDPGGCSQSSAQGAMSHCPLLLLMALLGAAGVHMC", "length": 505, "header": "tr|A0A8V0YCU1-1|A0A8V0YF11_CHICK Computationally mapped isoform of Netrin-G1 OS=Gallus gallus OX=9031 GN=NTNG1 PE=4 SV=1 CANONICAL=A0A8V0YF11-1" }, "locus": { "chromosome": "8", "start_pos": 975602, "end_pos": 838282, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028421.1", "url": "https://www.ensembl.org/id/ENSGALT00010028421.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016298.1", "url": "https://www.ensembl.org/id/ENSGALP00010016298.1" } ] } }, { "isoform_ac": "A0A8V0YCU6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF11/entry#A0A8V0YCU6-1", "sequence": { "sequence": "MYLSRFLSLHALWVTVSSMMQHYPSVWGHYDVCKTQIYTEEGKVWDYMACQPEARDMIKYVRVTLDPPDITCGDPPETFCAMGNPYMCNNECDASTQELAHPPELMFDLEGRHPSTFWQSTTWKDYPKPLHVNITLSWNKTIELTDNIVITFESGRPDQMILEKSLDYGRTWQPYQYYATDCLDAFHMDPKSVKDLSQHTVLEIICTEEYSTGYMTNSKIIHFEIKDRFAFFAGPRLHNMASLYGQLDTTKKLRDFFTITDLRIRLLRPATGEIYVDEQHLARYFYAISDIRVYGRCKCNLHATGCKEENKRLLCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANICIPSISSIGNPPKFDRIWPNISSLEVSKPNQANVCDNELLHCQNGGTCINNVRCQCPPAYTGILCEKLKCERDPGGCSQSSAQGAMSHCPLLLLMALLGAAGVHMC", "length": 459, "header": "tr|A0A8V0YCU6-1|A0A8V0YF11_CHICK Computationally mapped isoform of Netrin-G1 OS=Gallus gallus OX=9031 GN=NTNG1 PE=4 SV=1 CANONICAL=A0A8V0YF11-1" }, "locus": { "chromosome": "8", "start_pos": 975602, "end_pos": 838282, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028430.1", "url": "https://www.ensembl.org/id/ENSGALT00010028430.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016303.1", "url": "https://www.ensembl.org/id/ENSGALP00010016303.1" } ] } }, { "isoform_ac": "A0A8V0YF06-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF11/entry#A0A8V0YF06-1", "sequence": { "sequence": "MYLSRFLSLHALWVTVSSMMQHYPSVWGHYDVCKTQIYTEEGKVWDYMACQPEARDMIKYVRVTLDPPDITCGDPPETFCAMGNPYMCNNECDASTQELAHPPELMFDLEGRHPSTFWQSTTWKDYPKPLHVNITLSWNKTIELTDNIVITFESGRPDQMILEKSLDYGRTWQPYQYYATDCLDAFHMDPKSVKDLSQHTVLEIICTEEYSTGYMTNSKIIHFEIKDRFAFFAGPRLHNMASLYGQLDTTKKLRDFFTITDLRIRLLRPATGEIYVDEQHLARYFYAISDIRVYGRCKCNLHATGCKEENKRLLCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANIFLDMKKSTIHGRHGQKSELHLLHVRTASGNWRSHVASRRALLLSSPTSPLLVYPVFPVLVQMCVTMNSCTARMEGHASTMCGASALRPTLASYARSLSVKGIQEAAAKAPPRGQCHTVPYYC", "length": 475, "header": "tr|A0A8V0YF06-1|A0A8V0YF06_CHICK Computationally mapped isoform of Netrin G1 OS=Gallus gallus OX=9031 GN=NTNG1 PE=4 SV=1 CANONICAL=A0A8V0YF11-1" }, "locus": { "chromosome": "8", "start_pos": 975564, "end_pos": 838282, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028411.1", "url": "https://www.ensembl.org/id/ENSGALT00010028411.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016289.1", "url": "https://www.ensembl.org/id/ENSGALP00010016289.1" } ] } }, { "isoform_ac": "A0A8V0YF11-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF11/entry#A0A8V0YF11-1", "sequence": { "sequence": "MYLSRFLSLHALWVTVSSMMQHYPSVWGHYDVCKTQIYTEEGKVWDYMACQPEARDMIKYVRVTLDPPDITCGDPPETFCAMGNPYMCNNECDASTQELAHPPELMFDLEGRHPSTFWQSTTWKDYPKPLHVNITLSWNKTIELTDNIVITFESGRPDQMILEKSLDYGRTWQPYQYYATDCLDAFHMDPKSVKDLSQHTVLEIICTEEYSTGYMTNSKIIHFEIKDRFAFFAGPRLHNMASLYGQLDTTKKLRDFFTITDLRIRLLRPATGEIYVDEQHLARYFYAISDIRVYGRCKCNLHATGCKEENKRLLCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANICIPSISSIGNCECFGHSNRCSYIELLNTVICVSCKHNTRGQHCELCRLGYFRNASAELDDENVCIDCYCNPFGSVHDRCNDRGFCECKEGASGPKCDKCLPGYIWHSLGCQPNVCDNELLHCQNGGTCINNVRCQCPPAYTGILCEKLKCERDPGGCSQSSAQGAMSHCPLLLLMALLGAAGVHMC", "length": 539, "header": "tr|A0A8V0YF11-1|A0A8V0YF11_CHICK Isoform 1 of Netrin-G1 OS=Gallus gallus OX=9031 GN=NTNG1 PE=4 SV=1 CANONICAL=A0A8V0YF11-1" }, "locus": { "chromosome": "8", "start_pos": 975602, "end_pos": 838282, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028416.1", "url": "https://www.ensembl.org/id/ENSGALT00010028416.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016294.1", "url": "https://www.ensembl.org/id/ENSGALP00010016294.1" } ] } }, { "isoform_ac": "A0A8V0YF21-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF11/entry#A0A8V0YF21-1", "sequence": { "sequence": "MYLSRFLSLHALWVTVSSMMQHYPSVWGHYDVCKTQIYTEEGKVWDYMACQPEARDMIKYVRVTLDPPDITCGDPPETFCAMGNPYMCNNECDASTQELAHPPELMFDLEGRHPSTFWQSTTWKDYPKPLHVNITLSWNKTIELTDNIVITFESGRPDQMILEKSLDYGRTWQPYQYYATDCLDAFHMDPKSVKDLSQHTVLEIICTEEYSTGYMTNSKIIHFEIKDRFAFFAGPRLHNMASLYGQLDTTKKLRDFFTITDLRIRLLRPATGEIYVDEQHLARYFYAISDIRVYGRCKCNLHATGCKEENKRLLCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANICIPSISSIGNPPKFDRIWPNISSLEVSKPNQVAPKLSMTTVSSVQVANHKRDCECFGHSNRCSYIELLNTVICVSCKHNTRGQHCELCRLGYFRNASAELDDENVCIANVCDNELLHCQNGGTCINNVRCQCPPAYTGILCEKLKCERDPGGCSQSSAQGAMSHCPLLLLMALLGAAGVHMC", "length": 535, "header": "tr|A0A8V0YF21-1|A0A8V0YF21_CHICK Computationally mapped isoform of Netrin G1 OS=Gallus gallus OX=9031 GN=NTNG1 PE=4 SV=1 CANONICAL=A0A8V0YF11-1" }, "locus": { "chromosome": "8", "start_pos": 975602, "end_pos": 838282, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028431.1", "url": "https://www.ensembl.org/id/ENSGALT00010028431.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016304.1", "url": "https://www.ensembl.org/id/ENSGALP00010016304.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:424336", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424336", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287AGD8-1", "protein_name": "Netrin-G1", "gene_name": "NTNG1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MYLSRFLSIHALWVTVSSVMQPYPLVWGHYDVCKTQIYTEEGKVWDYMACQPESTDMTKYLKVKLDPPDITCGDPPETFCAMGNPYMCNNECDASTPELAHPPELMFDFEGRHPSTFWQSATWKEYPKPLQVNITLSWSKTIELTDNIVITFESGRPDQMILEKSLDYGRTWQPYQYYATDCLDAFHMDPKSVKDLSQHTVLEIICTEEYSTGYMTNSKIIHFEIKDRFAFFAGPWLRNMASLYGQLDTTKKLRDFFTVTDLRIRLLRPAVGEIFVDELHLARYFYAISDIKVHGRCKCNLHATVCVYDNSKLTCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCIPSISSIGNCECFGHSNRCSYIDLLNTVICVSCKHNTRGQHCELCRLGYFRNASAELDDENVCIECYCNPLGSVHDRCNGSGFCECKTGTTGPKCDECLPGNSWHYGCQPNVCDNELLHCQNGGTCHNNVRCLCPAAYTGILCEKLRCEEAGSCGSDSGQGAPPRGSPSLLLLAALLGITSPLGI", "length": 539 }, "evidence": [ { "id": "A0A8V0YF11", "url": "https://omabrowser.org/oma/group/A0A8V0YF11/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8I5ZNR9-1", "protein_name": "Netrin-G1", "gene_name": "Ntng1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MYLSRFLSIHALWVTVSSVMQPYPLVWGHYDVCKTQIYTEEGKVWDYMACQPESTDMTKYLKVKLDPPDITCGDPPESFCAMGNPYMCNNECDASTPELAHPPELMFDFEGRHPSTFWQSATWKEYPKPLQVNITLSWSKTIELTDNIVITFESGRPDQMILEKSLDYGRTWQPYQYYATDCLHAFHMDPKSVKDLSQHTVLEIICTEEYSTGYSTNSKIIHFEIKDRFAFFAGPRLRNMASLYGQLDTTKKLRDFFTVTDLRIRLLRPAVGEIFVDELHLARYFYAISDIKVRGRCKCNLHATMCVYDNSKLTCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTFVPALDSLSNCECFGHSNRCSYIDLLNTVICVSCKHNTRGQHCELCRLGYFRNASAQLDDENVCIECYCNPLGSIHDRCNGSGFCECKTGTTGPKCDECLPGNSWYYGCQPNVCDNELLHCQNGGTCHNNVRCVCPDAYTGILCEKLRCEEAGSCGSDSGQGAPPRGSPALLLLTVLLGTASPLVF", "length": 539 }, "evidence": [ { "id": "A0A8V0YF11", "url": "https://omabrowser.org/oma/group/A0A8V0YF11/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8R4G0-1", "protein_name": "Netrin-G1", "gene_name": "Ntng1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MYLSRFLSIHALWVTVSSVMQPYLFVWGHYDVCKSLIYTEEGKVWDYTACQPESTDMTKYLKVKLDPPDITCGDPPESFCAMGNPYMCNNECDASTPELAHPPELMFDFEGRHPSTFWQSATWKEYPKPLQVNITLSWSKTIELTDNIVITFESGRPDQMILEKSLDYGRTWQPYQYYATDCLHAFHMDPKSVKDLSQHTVLEIICTEEYSTGYSTNSKIIHFEIKDRFAFFAGPRLRNMASLYGQLDTTKKLRDFFTVTDLRIRLLRPAVGEIFVDELHLARYFYAISDIKVRGRCKCNLHATSCLYDNSKLTCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCIPSISSIGNCECFGHSNRCSYIDLLNTVICVSCKHNTRGQHCELCRLGYFRNASAQLDDENVCIECYCNPLGSIHDRCNGSGFCECKTGTTGPKCDECLPGNSWYYGCQPNVCDNELLHCQNGGTCQNNVRCACPDAYTGILCEKLRCEEAGSCGSESGQGAPPRGSPALLLLTMLLGTAGPLVF", "length": 539 }, "evidence": [ { "id": "A0A8V0YF11", "url": "https://omabrowser.org/oma/group/A0A8V0YF11/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9Y2I2-3", "protein_name": "Netrin-G1", "gene_name": "NTNG1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MYLSRFLSIHALWVTVSSVMQPYPLVWGHYDLCKTQIYTEEGKVWDYMACQPESTDMTKYLKVKLDPPDITCGDPPETFCAMGNPYMCNNECDASTPELAHPPELMFDFEGRHPSTFWQSATWKEYPKPLQVNITLSWSKTIELTDNIVITFESGRPDQMILEKSLDYGRTWQPYQYYATDCLDAFHMDPKSVKDLSQHTVLEIICTEEYSTGYTTNSKIIHFEIKDRFAFFAGPRLRNMASLYGQLDTTKKLRDFFTVTDLRIRLLRPAVGEIFVDELHLARYFYAISDIKVRGRCKCNLHATVCVYDNSKLTCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCIPSISSIGNCECFGHSNRCSYIDLLNTVICVSCKHNTRGQHCELCRLGYFRNASAQLDDENVCIECYCNPLGSIHDRCNGSGFCECKTGTTGPKCDECLPGNSWHYGCQPNVCDNELLHCQNGGTCHNNVRCLCPAAYTGILCEKLRCEEAGSCGSDSGQGAPPHGSPALLLLTTLLGTASPLVF", "length": 539 }, "evidence": [ { "id": "A0A8V0YF11", "url": "https://omabrowser.org/oma/group/A0A8V0YF11/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "glutamatergic synapse", "id": "GO:0098978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098978", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YF11", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF11" } ], "pmid": "" }, { "name": "presynaptic active zone membrane", "id": "GO:0048787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048787", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YF11", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF11" } ], "pmid": "" }, { "name": "Schaffer collateral - CA1 synapse", "id": "GO:0098685", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098685", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YF11", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF11" } ], "pmid": "" }, { "name": "side of membrane", "id": "GO:0098552", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098552", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YF11", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF11" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YF11", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF11" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 10, "go_terms": [ { "name": "axonogenesis", "id": "GO:0007409", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007409", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YF11", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF11" } ], "pmid": "" }, { "name": "animal organ morphogenesis", "id": "GO:0009887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009887", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YF11", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF11" } ], "pmid": "" }, { "name": "modulation of chemical synaptic transmission", "id": "GO:0050804", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050804", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YF11", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF11" } ], "pmid": "" }, { "name": "regulation of neuron projection development", "id": "GO:0010975", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010975", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YF11", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF11" } ], "pmid": "" }, { "name": "tissue development", "id": "GO:0009888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009888", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YF11", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF11" } ], "pmid": "" }, { "name": "synaptic membrane adhesion", "id": "GO:0099560", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099560", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YF11", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF11" } ], "pmid": "" }, { "name": "regulation of neuron migration", "id": "GO:2001222", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2001222", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YF11", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF11" } ], "pmid": "" }, { "name": "regulation of neuron projection arborization", "id": "GO:0150011", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0150011", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YF11", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF11" } ], "pmid": "" }, { "name": "nervous system development", "id": "GO:0007399", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007399", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YF11", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF11" } ], "pmid": "" }, { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YF11", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF11" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "cell-cell adhesion mediator activity", "id": "GO:0098632", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098632", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YF11", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF11" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 133, "end_pos": 135, "annotation": "n_glycosylation_sequon" }, { "start_pos": 139, "end_pos": 141, "annotation": "n_glycosylation_sequon" }, { "start_pos": 320, "end_pos": 322, "annotation": "n_glycosylation_sequon" }, { "start_pos": 406, "end_pos": 408, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YF11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF11" }, { "id": "PS50026", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50026" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "EGF-like", "eco_id": "ECO_0000259", "start_pos": 464, "end_pos": 499, "start_aa": "Gln", "end_aa": "Glu", "glycosite_overlap": "" }, { "evidence": [ { "id": 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"sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YHH2-1", "uniprot_ac": "A0A8V0YHH2", "uniprot_id": "A0A8V0YHH2_CHICK", "mass": { "chemical_mass": 53905.0, "monoisotopic_mass": 53905.0 }, "refseq": { "ac": "XP_040553268", "name": "serine/threonine-protein kinase 38-like isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040553268" }, "gene_names": [ { "name": "STK38L", "type": "recommended", "evidence": [ { "id": "A0A8V0YHH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHH2" } ] }, { "name": "STK38L", "type": "synonym", "evidence": [ { "id": "XP_040553268", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040553268" } ] } ], "protein_names": [ { "name": "non-specific serine/threonine protein kinase", "type": "recommended", "evidence": [ { "id": "A0A8V0YHH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHH2/entry#names_and_taxonomy" } ] }, { "name": "2.7.11.1", "type": "synonym", "evidence": [ { "id": "A0A8V0YHH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHH2/entry#names_and_taxonomy" } ] }, { "name": "serine/threonine-protein kinase 38-like isoform X2", "type": "synonym", "evidence": [ { "id": "XP_040553268", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040553268" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040553268", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040553268" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHH2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHH2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "STK38L", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHH2", "locus": { "chromosome": "1", "start_pos": 68204691, "end_pos": 68156522, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012896", "url": "https://www.ensembl.org/id/ENSGALG00010012896" } ] } } ], "crossref": [ { "id": "A0A8V0YHH2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YHH2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000014094", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000014094", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd05627", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05627", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "418217", "url": "https://www.ncbi.nlm.nih.gov/gene/418217", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000719", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000719", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000961", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000961", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008271", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008271", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011009", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011009", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017441", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017441", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017892", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017892", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050839", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050839", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PD57", "url": "https://www.orthodb.org/?gene=A0A1D5PD57", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YB42", "url": "https://www.orthodb.org/?gene=A0A8V0YB42", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YHH2", "url": "https://www.orthodb.org/?gene=A0A8V0YHH2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YPA9", "url": "https://www.orthodb.org/?gene=A0A8V0YPA9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22988", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22988", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22988:SF76", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22988:SF76", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00069", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00069", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00433", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00433", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_040553268", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040553268", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "17989", "url": "https://www.rhea-db.org/rhea/17989", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "46608", "url": "https://www.rhea-db.org/rhea/46608", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A1D5PD57", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PD57", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PD57-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PD57-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YB42", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB42", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YB42-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB42-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHH2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHH2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHH2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHH2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YPA9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPA9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YPA9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPA9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAMTAGTTTSFPMSNHTRERVTVAKLTLENFYSNLIIQHEERETRQKKLEVAMDEEGLADEEKKLRRSQHARKETEFLRLKRTRLGLDDFESLKVIGRGAFGEVRLVQKKDTGHIYAMKILRKADMLEKEQVAHIRAERDILVEADGAWVVKMFYSFQDKRNLYLIMEFLPGGDMMTLLMKKDTLSEEETQFYISETVLAIDAIHQLGFIHRDIKPDNLLLDAKGHVKLSDFGLCTGLKKAHRTEFYRNLTHNPPSDFSFQNMNSKRKAETWKKNRRQLAYSTVGTPDYIAPEVFMQTGYNKLCDWWSLGVIMYEMLIGYPPFCSETPQETYRKVMNWKETLVFPPEVPISEKAKDLILRFCTDSENRIGSNGVEEIKSHPFFEGVDWGHIRERPAAIPIEIKSIDDTSNFDEFPESDILQPVPNTTEPDYKSKDWVFLNYTYKRFEGLTQRGSIPTYMKAGKL", "length": 464, "header": "tr|A0A8V0YHH2-1|A0A8V0YHH2_CHICK Isoform 1 of non-specific serine/threonine protein kinase OS=Gallus gallus OX=9031 GN=STK38L PE=1 SV=1 CANONICAL=A0A8V0YHH2-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PD57-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHH2/entry#A0A1D5PD57-1", "sequence": { "sequence": "MCLDLATFFNQEGDVCVTMAMTAGTTTSFPMSNHTRERVTVAKLTLENFYSNLIIQHEERETRQKKLEVAMDEEGLADEEKKLRRSQHARKETEFLRLKRTRLGLDDFESLKVIGRGAFGEVRLVQKKDTGHIYAMKILRKADMLEKEQVAHIRAERDILVEADGAWVVKMFYSFQDKRNLYLIMEFLPGGDMMTLLMKKDTLSEEETQFYISETVLAIDAIHQLGFIHRDIKPDNLLLDAKGHVKLSDFGLCTGLKKAHRTEFYRNLTHNPPSDFSFQNMNSKRKAETWKKNRRQLAYSTVGTPDYIAPEVFMQTGYNKLCDWWSLGVIMYEMLIGYPPFCSETPQETYRKVMNWKETLVFPPEVPISEKAKDLILRFCTDSENRIGSNGVEEIKSHPFFEGVDWGHIRERPAAIPIEIKSIDDTSNFDEFPESDILQPVPNTTEPDYKSKDWVFLNYTYKRFEGLTQRGSIPTYMKAGKL", "length": 482, "header": "tr|A0A1D5PD57-1|A0A1D5PD57_CHICK Computationally mapped isoform of non-specific serine/threonine protein kinase OS=Gallus gallus OX=9031 GN=STK38L PE=1 SV=1 CANONICAL=A0A8V0YHH2-1" }, "locus": { "chromosome": "1", "start_pos": 68200671, "end_pos": 68181746, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030949.1", "url": "https://www.ensembl.org/id/ENSGALT00010030949.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017981.1", "url": "https://www.ensembl.org/id/ENSGALP00010017981.1" } ] } }, { "isoform_ac": "A0A8V0YB42-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHH2/entry#A0A8V0YB42-1", "sequence": { "sequence": "MLVPAGMVVVLPPPFTALICKVCVTMAMTAGTTTSFPMSNHTRERVTVAKLTLENFYSNLIIQHEERETRQKKLEVAMDEEGLADEEKKLRRSQHARKETEFLRLKRTRLGLDDFESLKVIGRGAFGEVRLVQKKDTGHIYAMKILRKADMLEKEQVAHIRAERDILVEADGAWVVKMFYSFQDKRNLYLIMEFLPGGDMMTLLMKKDTLSEEETQFYISETVLAIDAIHQLGFIHRDIKPDNLLLDAKGHVKLSDFGLCTGLKKAHRTEFYRNLTHNPPSDFSFQNMNSKRKAETWKKNRRQLAYSTVGTPDYIAPEVFMQTGYNKLCDWWSLGVIMYEMLIGYPPFCSETPQETYRKVMNWKETLVFPPEVPISEKAKDLILRFCTDSENRIGSNGVEEIKSHPFFEGVDWGHIRERPAAIPIEIKSIDDTSNFDEFPESDILQPVPNTTEPDYKSKDWVFLNYTYKRFEGLTQRGSIPTYMKAGKL", "length": 489, "header": "tr|A0A8V0YB42-1|A0A8V0YB42_CHICK Computationally mapped isoform of non-specific serine/threonine protein kinase OS=Gallus gallus OX=9031 GN=STK38L PE=1 SV=1 CANONICAL=A0A8V0YHH2-1" }, "locus": { "chromosome": "1", "start_pos": 68200671, "end_pos": 68156539, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030964.1", "url": "https://www.ensembl.org/id/ENSGALT00010030964.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017991.1", "url": "https://www.ensembl.org/id/ENSGALP00010017991.1" } ] } }, { "isoform_ac": "A0A8V0YHH2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHH2/entry#A0A8V0YHH2-1", "sequence": { "sequence": "MAMTAGTTTSFPMSNHTRERVTVAKLTLENFYSNLIIQHEERETRQKKLEVAMDEEGLADEEKKLRRSQHARKETEFLRLKRTRLGLDDFESLKVIGRGAFGEVRLVQKKDTGHIYAMKILRKADMLEKEQVAHIRAERDILVEADGAWVVKMFYSFQDKRNLYLIMEFLPGGDMMTLLMKKDTLSEEETQFYISETVLAIDAIHQLGFIHRDIKPDNLLLDAKGHVKLSDFGLCTGLKKAHRTEFYRNLTHNPPSDFSFQNMNSKRKAETWKKNRRQLAYSTVGTPDYIAPEVFMQTGYNKLCDWWSLGVIMYEMLIGYPPFCSETPQETYRKVMNWKETLVFPPEVPISEKAKDLILRFCTDSENRIGSNGVEEIKSHPFFEGVDWGHIRERPAAIPIEIKSIDDTSNFDEFPESDILQPVPNTTEPDYKSKDWVFLNYTYKRFEGLTQRGSIPTYMKAGKL", "length": 464, "header": "tr|A0A8V0YHH2-1|A0A8V0YHH2_CHICK Isoform 1 of non-specific serine/threonine protein kinase OS=Gallus gallus OX=9031 GN=STK38L PE=1 SV=1 CANONICAL=A0A8V0YHH2-1" }, "locus": { "chromosome": "1", "start_pos": 68200671, "end_pos": 68185737, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030957.1", "url": "https://www.ensembl.org/id/ENSGALT00010030957.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017988.1", "url": "https://www.ensembl.org/id/ENSGALP00010017988.1" } ] } }, { "isoform_ac": "A0A8V0YPA9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHH2/entry#A0A8V0YPA9-1", "sequence": { "sequence": "MFLPSVCVTMAMTAGTTTSFPMSNHTRERVTVAKLTLENFYSNLIIQHEERETRQKKLEVAMDEEGLADEEKKLRRSQHARKETEFLRLKRTRLGLDDFESLKVIGRGAFGEVRLVQKKDTGHIYAMKILRKADMLEKEQVAHIRAERDILVEADGAWVVKMFYSFQDKRNLYLIMEFLPGGDMMTLLMKKDTLSEEETQFYISETVLAIDAIHQLGFIHRDIKPDNLLLDAKGHVKLSDFGLCTGLKKAHRTEFYRNLTHNPPSDFSFQNMNSKRKAETWKKNRRQLAYSTVGTPDYIAPEVFMQTGYNKLCDWWSLGVIMYEMLIGYPPFCSETPQETYRKVMNWKETLVFPPEVPISEKAKDLILRFCTDSENRIGSNGVEEIKSHPFFEGVDWGHIRERPAAIPIEIKSIDDTSNFDEFPESDILQPVPNTTEPDYKSKDWVFLNYTYKRFEGLTQRGSIPTYMKAGKL", "length": 473, "header": "tr|A0A8V0YPA9-1|A0A8V0YPA9_CHICK Computationally mapped isoform of non-specific serine/threonine protein kinase OS=Gallus gallus OX=9031 GN=STK38L PE=1 SV=1 CANONICAL=A0A8V0YHH2-1" }, "locus": { "chromosome": "1", "start_pos": 68200671, "end_pos": 68179073, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030950.1", "url": "https://www.ensembl.org/id/ENSGALT00010030950.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017982.1", "url": "https://www.ensembl.org/id/ENSGALP00010017982.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "magnesium ion binding", "id": "GO:0000287", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000287", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHH2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHH2" } ], "pmid": "" }, { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHH2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHH2" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHH2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHH2" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHH2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHH2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHH2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHH2" } ], "pmid": "" }, { "name": "actin cytoskeleton", "id": "GO:0015629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015629", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHH2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHH2" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHH2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHH2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "intracellular signal transduction", "id": "GO:0035556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035556", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHH2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHH2" } ], "pmid": "" }, { "name": "negative regulation of autophagy", "id": "GO:0010507", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010507", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YHH2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHH2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 15, "end_pos": 17, "annotation": "n_glycosylation_sequon" }, { "start_pos": 249, "end_pos": 251, "annotation": "n_glycosylation_sequon" }, { "start_pos": 425, "end_pos": 427, "annotation": "n_glycosylation_sequon" }, { "start_pos": 440, "end_pos": 442, "annotation": 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"ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0X1Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X1Q7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0X1Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X1Q7" } ] } ] }, { "uniprot_ac": "A0A8V0X2Y2", "gene_name": "MAPK12", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X2Y2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X2Y2" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0X2Y2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X2Y2" } ] } ] }, { "uniprot_ac": "A0A8V0X3D6", "gene_name": "LOC100858386", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X3D6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X3D6" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0X3D6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X3D6" } ] } ] }, { "uniprot_ac": "A0A8V0X4P0", "gene_name": "CDKL5", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X4P0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X4P0" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0X4P0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X4P0" } ] } ] }, { "uniprot_ac": "A0A8V0X4Q3", "gene_name": "ICK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X4Q3", "database": "UniProtKB", "url": 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"ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0X6T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X6T4" } ] } ] }, { "uniprot_ac": "A0A8V0X7R2", "gene_name": "SBK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X7R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X7R2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0X7R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X7R2" } ] } ] }, { "uniprot_ac": "A0A8V0X8M1", "gene_name": "TRIO", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X8M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X8M1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": 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[ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XDR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XDR5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XDR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XDR5" } ] } ] }, { "uniprot_ac": "A0A8V0XE48", "gene_name": "ROCK2", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XE48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XE48" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "A0A8V0XE48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XE48" } ] } ] }, { "uniprot_ac": "A0A8V0XEA3", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XEA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEA3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XEA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEA3" } ] } ] }, { "uniprot_ac": "A0A8V0XFW1", "gene_name": "SGK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XFW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XFW1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XFW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XFW1" } ] } ] }, { "uniprot_ac": "A0A8V0XFX2", "gene_name": "NEK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": 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"ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0XLV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XLV6" } ] } ] }, { "uniprot_ac": "A0A8V0XMT1", "gene_name": "MOS", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XMT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMT1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XMT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMT1" } ] } ] }, { "uniprot_ac": "A0A8V0XMX8", "gene_name": "MASTL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XMX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMX8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": 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= O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQQ4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQQ4" } ] } ] }, { "uniprot_ac": "A0A8V0XQS0", "gene_name": "STK24", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XQS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQS0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XQS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQS0" } ] } ] }, { "uniprot_ac": "A0A8V0XS42", "gene_name": "MAP3K4", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XS42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XS42" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0XS42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XS42" } ] } ] }, { "uniprot_ac": "A0A8V0XU71", "gene_name": "MYO3A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XU71", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XU71" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XU71", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XU71" } ] } ] }, { "uniprot_ac": "A0A8V0XU96", "gene_name": "PRKD1", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XU96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XU96" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V0XU96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XU96" } ] } ] }, { "uniprot_ac": "A0A8V0XUM6", "gene_name": "LATS1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XUM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XUM6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XUM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XUM6" } ] } ] }, { "uniprot_ac": "A0A8V0XW11", "gene_name": "RPS6KA2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XW11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XW11" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XW11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XW11" } ] } ] }, { "uniprot_ac": "A0A8V0XW29", "gene_name": "CDKL2", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XW29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XW29" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0XW29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XW29" } ] } ] }, { "uniprot_ac": "A0A8V0XXB8", "gene_name": "MAPK15", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XXB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XXB8" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0XXB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XXB8" } ] } ] }, { "uniprot_ac": "A0A8V0Y074", "gene_name": "NEK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y074", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y074" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y074", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y074" } ] } ] }, { "uniprot_ac": "A0A8V0Y241", "gene_name": "LOC426385", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y241", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y241" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y241", "database": "UniProtKB", "url": 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O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YFH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFH4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YFH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFH4" } ] } ] }, { "uniprot_ac": "A0A8V0YFL1", "gene_name": "CDK19", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YFL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFL1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0YFL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFL1" } ] } ] }, { "uniprot_ac": "A0A8V0YFP8", "gene_name": "RIPK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YFP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFP8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YFP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFP8" } ] } ] }, { "uniprot_ac": "A0A8V0YFR6", "gene_name": "TNIK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YFR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFR6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YFR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFR6" } ] } ] }, { "uniprot_ac": "A0A8V0YGW2", "gene_name": "STK32B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YGW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGW2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YGW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGW2" } ] } ] }, { "uniprot_ac": "A0A8V0YHH2", "gene_name": "STK38L", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YHH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHH2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YHH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHH2" } ] } ] }, { "uniprot_ac": "A0A8V0YHN2", "gene_name": "RPS6KA1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YHN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHN2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YHN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHN2" } ] } ] }, { "uniprot_ac": "A0A8V0YIV6", "gene_name": "DYRK1A", "activity": [ { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] }, { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] } ] }, { "uniprot_ac": "A0A8V0YJP9", "gene_name": "RIOK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YJP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJP9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YJP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJP9" } ] } ] }, { "uniprot_ac": "A0A8V0YK18", "gene_name": "CDC42BPB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YK18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK18" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YK18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK18" } ] } ] }, { "uniprot_ac": "A0A8V0YKK3", "gene_name": "MAP4K4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YKK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKK3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YKK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKK3" } ] } ] }, { "uniprot_ac": "A0A8V0YLV1", "gene_name": "MARK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YLV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLV1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YLV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLV1" } ] } ] }, { "uniprot_ac": "A0A8V0YM22", "gene_name": "MYO3AL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YM22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM22" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YM22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM22" } ] } ] }, { "uniprot_ac": "A0A8V0YM96", "gene_name": "STK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YM96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM96" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YM96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM96" } ] } ] }, { "uniprot_ac": "A0A8V0YMB3", "gene_name": "STK32A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YMB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMB3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YMB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMB3" } ] } ] }, { "uniprot_ac": "A0A8V0YMN5", "gene_name": "BRAF", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YMN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMN5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YMN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMN5" } ] } ] }, { "uniprot_ac": "A0A8V0YNI5", "gene_name": "NIM1K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + 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"ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YRC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRC9" } ] } ] }, { "uniprot_ac": "A0A8V0YRN4", "gene_name": "GAK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YRN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRN4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YRN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRN4" } ] } ] }, { "uniprot_ac": "A0A8V0YSH3", "gene_name": "RPS6KA6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YSH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSH3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": 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"A0A8V0YXZ5", "gene_name": "CDC42BPA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YXZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXZ5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YXZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXZ5" } ] } ] }, { "uniprot_ac": "A0A8V0YYX2", "gene_name": "PAK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YYX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYX2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YYX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYX2" } ] } ] }, { "uniprot_ac": "A0A8V0YYZ3", "gene_name": "SPEG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YYZ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYZ3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YYZ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYZ3" } ] } ] }, { "uniprot_ac": "A0A8V0YZ74", "gene_name": "MAP2K5", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZ74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZ74" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V0YZ74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZ74" } ] } ] }, { "uniprot_ac": "A0A8V0YZF2", "gene_name": "PAK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZF2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YZF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZF2" } ] } ] }, { "uniprot_ac": "A0A8V0YZK0", "gene_name": "MAP3K6", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZK0" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0YZK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZK0" } ] } ] }, { "uniprot_ac": "A0A8V0YZM1", "gene_name": "MOK", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZM1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0YZM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZM1" } ] }, { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZM1" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0YZM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZM1" } ] } ] }, { "uniprot_ac": "A0A8V0YZV9", "gene_name": "ATR", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZV9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YZV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZV9" } ] } ] }, { "uniprot_ac": "A0A8V0YZY4", "gene_name": "SBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZY4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YZY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZY4" } ] } ] }, { "uniprot_ac": "A0A8V0Z124", "gene_name": "VRK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z124", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z124" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z124", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z124" } ] } ] }, { "uniprot_ac": "A0A8V0Z157", "gene_name": "MARK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z157", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z157" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z157", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z157" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A8V0Z157", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z157" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z157", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z157" } ] } ] }, { "uniprot_ac": "A0A8V0Z1X0", "gene_name": "MAP4K3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z1X0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1X0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z1X0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1X0" } ] } ] }, { "uniprot_ac": "A0A8V0Z283", "gene_name": "MARK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z283", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z283" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z283", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z283" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A8V0Z283", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z283" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z283", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z283" } ] } ] }, { "uniprot_ac": "A0A8V0Z2E3", "gene_name": "PDIK1L", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z2E3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2E3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z2E3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2E3" } ] } ] }, { "uniprot_ac": "A0A8V0Z2Z3", "gene_name": "AAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z2Z3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2Z3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z2Z3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2Z3" } ] } ] }, { "uniprot_ac": "A0A8V0Z466", "gene_name": "MAP3K19", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z466", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z466" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z466", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z466" } ] } ] }, { "uniprot_ac": "A0A8V0Z6K4", "gene_name": "PIK3R4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z6K4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6K4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z6K4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6K4" } ] } ] }, { "uniprot_ac": "A0A8V0Z6T1", "gene_name": "ERN2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z6T1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6T1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z6T1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6T1" } ] } ] }, { "uniprot_ac": "A0A8V0Z807", "gene_name": "NEK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z807", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z807" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z807", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z807" } ] } ] }, { "uniprot_ac": "A0A8V0Z8G2", "gene_name": "TTBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z8G2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8G2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z8G2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8G2" } ] } ] }, { "uniprot_ac": "A0A8V0Z8T4", "gene_name": "RPS6KC1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z8T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8T4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z8T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8T4" } ] } ] }, { "uniprot_ac": "A0A8V0Z927", "gene_name": "PINK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z927", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z927" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z927", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z927" } ] } ] }, { "uniprot_ac": "A0A8V0Z930", "gene_name": "CAMK2B", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z930", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z930" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V0Z930", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z930" } ] } ] }, { "uniprot_ac": "A0A8V0Z9J0", "gene_name": "CIT", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z9J0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9J0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z9J0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9J0" } ] } ] }, { "uniprot_ac": "A0A8V0ZA06", "gene_name": "CDKL1", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZA06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA06" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0ZA06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA06" } ] } ] }, { "uniprot_ac": "A0A8V0ZA45", "gene_name": "MAP4K5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZA45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA45" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZA45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA45" } ] } ] }, { "uniprot_ac": "A0A8V0ZB33", "gene_name": "CAMK2G", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZB33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB33" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V0ZB33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB33" } ] } ] }, { "uniprot_ac": "A0A8V0ZB38", "gene_name": "CIITA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZB38", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB38" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZB38", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB38" } ] } ] }, { "uniprot_ac": "A0A8V0ZBN6", "gene_name": "MAP2K1", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZBN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBN6" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V0ZBN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBN6" } ] } ] }, { "uniprot_ac": "A0A8V0ZBZ2", "gene_name": "MAP3K9", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZBZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBZ2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0ZBZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBZ2" } ] } ] }, { "uniprot_ac": "A0A8V0ZC16", "gene_name": "KALRN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZC16", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC16" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZC16", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC16" } ] } ] }, { "uniprot_ac": "A0A8V0ZD40", "gene_name": "CDC2L1", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD40" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD40" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A8V0ZD40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD40" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0ZD40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD40" } ] } ] }, { "uniprot_ac": "A0A8V0ZD48", "gene_name": "PRKCE", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD48" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V0ZD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD48" } ] } ] }, { "uniprot_ac": "A0A8V0ZD60", "gene_name": "STK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD60" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZD60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD60" } ] } ] }, { "uniprot_ac": "A0A8V0ZD70", "gene_name": "DCLK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD70" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZD70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD70" } ] } ] }, { "uniprot_ac": "A0A8V0ZDW9", "gene_name": "NEK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZDW9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDW9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZDW9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDW9" } ] } ] }, { "uniprot_ac": "A0A8V0ZFM2", "gene_name": "LMTK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZFM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFM2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZFM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFM2" } ] } ] }, { "uniprot_ac": "A0A8V0ZFP1", "gene_name": "TTBK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZFP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFP1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZFP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFP1" } ] } ] }, { "uniprot_ac": "A0A8V0ZFT3", "gene_name": "LRRK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZFT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFT3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZFT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFT3" } ] } ] }, { "uniprot_ac": "A0A8V0ZGY3", "gene_name": "HIPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZGY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGY3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZGY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGY3" } ] } ] }, { "uniprot_ac": "A0A8V0ZH91", "gene_name": "WNK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZH91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH91" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZH91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH91" } ] } ] }, { "uniprot_ac": "A0A8V0ZI32", "gene_name": "STK16", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZI32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI32" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZI32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI32" } ] } ] }, { "uniprot_ac": "A0A8V0ZK64", "gene_name": "PDPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZK64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK64" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZK64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK64" } ] } ] }, { "uniprot_ac": "A0A8V0ZKA2", "gene_name": "EIF2AK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZKA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKA2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZKA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKA2" } ] } ] }, { "uniprot_ac": "A0A8V0ZKM9", "gene_name": "STK36", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZKM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKM9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZKM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKM9" } ] } ] }, { "uniprot_ac": "A0A8V0ZLU3", "gene_name": "TLK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZLU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLU3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZLU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLU3" } ] } ] }, { "uniprot_ac": "A0A8V0ZMK1", "gene_name": "PIKFYVE", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZMK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMK1" } ] }, { "ec_number": "2.7.1.150", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,5-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZMK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMK1" } ] }, { "ec_number": "2.7.1.150", "activity": "", "evidence": [ { "id": "A0A8V0ZMK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMK1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZMK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMK1" } ] } ] }, { "uniprot_ac": "A0A8V0ZNP7", "gene_name": "SGK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZNP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNP7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZNP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNP7" } ] } ] }, { "uniprot_ac": "A0A8V0ZPX2", "gene_name": "ALPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZPX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPX2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZPX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPX2" } ] } ] }, { "uniprot_ac": "A0A8V0ZQJ2", "gene_name": "RPS6KB2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZQJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQJ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZQJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQJ2" } ] } ] }, { "uniprot_ac": "A0A8V0ZQT5", "gene_name": "SLC13A3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZQT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQT5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZQT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQT5" } ] } ] }, { "uniprot_ac": "A0A8V0ZRX1", "gene_name": "SETD6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZRX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRX1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZRX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRX1" } ] }, { "ec_number": "2.1.1.-", "activity": "", "evidence": [ { "id": "A0A8V0ZRX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRX1" } ] } ] }, { "uniprot_ac": "A0A8V0ZSB4", "gene_name": "SIK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZSB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSB4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZSB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSB4" } ] } ] }, { "uniprot_ac": "A0A8V0ZSP4", "gene_name": "PKN2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZSP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSP4" } ] }, { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZSP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSP4" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V0ZSP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSP4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZSP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSP4" } ] } ] }, { "uniprot_ac": "A0A8V0ZT63", "gene_name": "STK25", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZT63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT63" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZT63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT63" } ] } ] }, { "uniprot_ac": "A0A8V0ZUC6", "gene_name": "PAK6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZUC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUC6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZUC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUC6" } ] } ] }, { "uniprot_ac": "A0A8V0ZUL0", "gene_name": "PASK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZUL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUL0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZUL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUL0" } ] } ] }, { "uniprot_ac": "A0A8V0ZUU8", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZUU8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUU8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZUU8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUU8" } ] } ] }, { "uniprot_ac": "A0A8V0ZUU9", "gene_name": "MKNK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZUU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUU9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZUU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUU9" } ] } ] }, { "uniprot_ac": "A0A8V0ZWC7", "gene_name": "EIF2AK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZWC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWC7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZWC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWC7" } ] } ] }, { "uniprot_ac": "A0A8V0ZWW1", "gene_name": "MAP3K12", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZWW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWW1" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0ZWW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWW1" } ] } ] }, { "uniprot_ac": "A0A8V0ZXQ9", "gene_name": "PRKG1", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZXQ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXQ9" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "A0A8V0ZXQ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXQ9" } ] } ] }, { "uniprot_ac": "A0A8V0ZYU6", "gene_name": "TNNI3K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZYU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZYU6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZYU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZYU6" } ] } ] }, { "uniprot_ac": "A0A8V0ZZE4", "gene_name": "OBSCN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZZE4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZE4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZZE4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZE4" } ] } ] }, { "uniprot_ac": "A0A8V0ZZK5", "gene_name": "STK38", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZZK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZK5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZZK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZK5" } ] } ] }, { "uniprot_ac": "A0A8V0ZZV3", "gene_name": "MYO3B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZZV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZV3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZZV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZV3" } ] } ] }, { "uniprot_ac": "A0A8V1A069", "gene_name": "TESK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A069", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A069" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V1A069", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A069" } ] } ] }, { "uniprot_ac": "A0A8V1A0W4", "gene_name": "ULK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A0W4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0W4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A0W4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0W4" } ] } ] }, { "uniprot_ac": "A0A8V1A0Y8", "gene_name": "MAST2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A0Y8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0Y8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A0Y8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0Y8" } ] } ] }, { "uniprot_ac": "A0A8V1A1P3", "gene_name": "SRPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A1P3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1P3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A1P3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1P3" } ] } ] }, { "uniprot_ac": "A0A8V1A1Y7", "gene_name": "CDK2", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A1Y7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1Y7" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V1A1Y7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1Y7" } ] } ] }, { "uniprot_ac": "A0A8V1A2T9", "gene_name": "MAP3K14", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A2T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2T9" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V1A2T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2T9" } ] } ] }, { "uniprot_ac": "A0A8V1A3T8", "gene_name": "MAST3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A3T8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3T8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A3T8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3T8" } ] } ] }, { "uniprot_ac": "A0A8V1A4A1", "gene_name": "CAMKK2", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4A1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4A1" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V1A4A1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4A1" } ] } ] }, { "uniprot_ac": "A0A8V1A4J8", "gene_name": "MAPKAPK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4J8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4J8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A4J8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4J8" } ] } ] }, { "uniprot_ac": "A0A8V1A4Q4", "gene_name": "MAPK3", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4Q4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4Q4" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V1A4Q4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4Q4" } ] } ] }, { "uniprot_ac": "A0A8V1A4V7", "gene_name": "HIPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4V7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4V7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A4V7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4V7" } ] } ] }, { "uniprot_ac": "A0A8V1A513", "gene_name": "DAPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A513", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A513" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A513", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A513" } ] } ] }, { "uniprot_ac": "A0A8V1A675", "gene_name": "CSNK1G2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A675", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A675" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A675", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A675" } ] } ] }, { "uniprot_ac": "A0A8V1A7E0", "gene_name": "DYRK3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7E0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E0" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V1A7E0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E0" } ] } ] }, { "uniprot_ac": "A0A8V1A7E9", "gene_name": "SIK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7E9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A7E9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E9" } ] } ] }, { "uniprot_ac": "A0A8V1A7M0", "gene_name": "STK39", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7M0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7M0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A7M0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7M0" } ] } ] }, { "uniprot_ac": "A0A8V1A7P9", "gene_name": "DCAF1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A7P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P9" } ] } ] }, { "uniprot_ac": "A0A8V1A9S5", "gene_name": "NUAK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A9S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9S5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A9S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9S5" } ] } ] }, { "uniprot_ac": "A0A8V1ABF3", "gene_name": "PRKAA2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] } ] }, { "uniprot_ac": "A0A8V1ABP4", "gene_name": "DSTYK", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABP4" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V1ABP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABP4" } ] } ] }, { "uniprot_ac": "A0A8V1ABR8", "gene_name": "CAMK4L", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABR8" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V1ABR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABR8" } ] } ] }, { "uniprot_ac": "A0A8V1AC40", "gene_name": "CDK18", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AC40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC40" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V1AC40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC40" } ] } ] }, { "uniprot_ac": "A0A8V1ACB5", "gene_name": "MAPK13", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACB5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V1ACB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACB5" } ] } ] }, { "uniprot_ac": "A0A8V1ACF6", "gene_name": "PIM1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACF6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ACF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACF6" } ] } ] }, { "uniprot_ac": "A0A8V1ACK0", "gene_name": "MAPKAPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACK0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ACK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACK0" } ] } ] }, { "uniprot_ac": "A0A8V1ACW2", "gene_name": "WNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACW2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ACW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACW2" } ] } ] }, { "uniprot_ac": "A0A8V1ADF0", "gene_name": "MAP2K2", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ADF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADF0" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V1ADF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADF0" } ] } ] }, { "uniprot_ac": "A0A8V1ADN9", "gene_name": "NLK", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ADN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADN9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V1ADN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADN9" } ] } ] }, { "uniprot_ac": "A0A8V1ADT4", "gene_name": "MKNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ADT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADT4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ADT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADT4" } ] } ] }, { "uniprot_ac": "A0A8V1AE45", "gene_name": "ERN1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AE45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE45" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AE45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE45" } ] } ] }, { "uniprot_ac": "A0A8V1AEH4", "gene_name": "STK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AEH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEH4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AEH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEH4" } ] } ] }, { "uniprot_ac": "A0A8V1AFS4", "gene_name": "STKLD1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AFS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFS4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AFS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFS4" } ] } ] }, { "uniprot_ac": "A0A8V1AG70", "gene_name": "LOC100857512", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AG70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AG70" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AG70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AG70" } ] } ] }, { "uniprot_ac": "A0A8V1AH12", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AH12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH12" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AH12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH12" } ] } ] }, { "uniprot_ac": "A0A8V1AHA8", "gene_name": "NEK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AHA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHA8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AHA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHA8" } ] } ] }, { "uniprot_ac": "A0A8V1AIY7", "gene_name": "AATK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AIY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIY7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AIY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIY7" } ] } ] }, { "uniprot_ac": "A0A8V1AJA4", "gene_name": "RPS6KB1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AJA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJA4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AJA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJA4" } ] } ] }, { "uniprot_ac": "A0A8V1AKW4", "gene_name": "MAP2K4", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AKW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKW4" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V1AKW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKW4" } ] } ] }, { "uniprot_ac": "A0A8V1AM12", "gene_name": "GSG2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AM12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM12" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AM12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM12" } ] } ] }, { "uniprot_ac": "A0A8V1AMK5", "gene_name": "PRKCA", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AMK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMK5" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V1AMK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMK5" } ] } ] }, { "uniprot_ac": "A0A8V1AMQ2", "gene_name": "CAMKK1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AMQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMQ2" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V1AMQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMQ2" } ] } ] }, { "uniprot_ac": "A0A8V1AP60", "gene_name": "KSR1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AP60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP60" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AP60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP60" } ] } ] }, { "uniprot_ac": "E1BQN6", "gene_name": "PRKCZ", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BQN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQN6" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1BQN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQN6" } ] } ] }, { "uniprot_ac": "E1BQV7", "gene_name": "SLK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BQV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQV7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BQV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQV7" } ] } ] }, { "uniprot_ac": "E1BUG0", "gene_name": "CDK12", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] } ] }, { "uniprot_ac": "E1BW33", "gene_name": "SMG1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BW33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BW33" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BW33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BW33" } ] } ] }, { "uniprot_ac": "E1BWA3", "gene_name": "PRKCI", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BWA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWA3" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1BWA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWA3" } ] } ] }, { "uniprot_ac": "E1BWT0", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BWT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWT0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BWT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWT0" } ] } ] }, { "uniprot_ac": "E1BX69", "gene_name": "EIF2AK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BX69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BX69" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BX69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BX69" } ] } ] }, { "uniprot_ac": "E1BY69", "gene_name": "PIM3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BY69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BY69" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BY69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BY69" } ] } ] }, { "uniprot_ac": "E1BYH2", "gene_name": "TAOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BYH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BYH2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BYH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BYH2" } ] } ] }, { "uniprot_ac": "E1C093", "gene_name": "PIK3CG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.154", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.154", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] } ] }, { "uniprot_ac": "E1C2I2", "gene_name": "MASTL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C2I2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C2I2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C2I2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C2I2" } ] } ] }, { "uniprot_ac": "E1C581", "gene_name": "TBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C581", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C581" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C581", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C581" } ] } ] }, { "uniprot_ac": "E1C6T4", "gene_name": "PRKD3", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C6T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C6T4" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1C6T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C6T4" } ] } ] }, { "uniprot_ac": "E1C764", "gene_name": "BMP2K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C764", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C764" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C764", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C764" } ] } ] }, { "uniprot_ac": "E1C848", "gene_name": "MAP3K8", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C848", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C848" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1C848", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C848" } ] } ] }, { "uniprot_ac": "F1NA68", "gene_name": "CDK3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NA68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NA68" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1NA68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NA68" } ] } ] }, { "uniprot_ac": "F1NB57", "gene_name": "PLK2", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NB57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NB57" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "F1NB57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NB57" } ] } ] }, { "uniprot_ac": "F1NBT0", "gene_name": "STK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NBT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NBT0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1NBT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NBT0" } ] } ] }, { "uniprot_ac": "F1NCX7", "gene_name": "PLK1", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NCX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCX7" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "F1NCX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCX7" } ] } ] }, { "uniprot_ac": "F1NCY7", "gene_name": "MAPKAPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NCY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCY7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1NCY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCY7" } ] } ] }, { "uniprot_ac": "F1NJH1", "gene_name": "PRKCH", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NJH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NJH1" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1NJH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NJH1" } ] } ] }, { "uniprot_ac": "F1NKW3", "gene_name": "MAP3K15", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NKW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NKW3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1NKW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NKW3" } ] } ] }, { "uniprot_ac": "F1NLR7", "gene_name": "CLK3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NLR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NLR7" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "F1NLR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NLR7" } ] } ] }, { "uniprot_ac": "F1NUX4", "gene_name": "MTOR", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NUX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NUX4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1NUX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NUX4" } ] } ] }, { "uniprot_ac": "F1NVF2", "gene_name": "MAP2K6", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NVF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NVF2" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "F1NVF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NVF2" } ] } ] }, { "uniprot_ac": "F1P011", "gene_name": "CAMK2A", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1P011", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P011" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "F1P011", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P011" } ] } ] }, { "uniprot_ac": "F1P356", "gene_name": "NUAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1P356", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P356" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1P356", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P356" } ] } ] }, { "uniprot_ac": "F1P4G3", "gene_name": 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O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P10741", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P10741" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P10741", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P10741" } ] } ] }, { "uniprot_ac": "P13863", "gene_name": "CDK1", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P13863", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13863" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "P13863", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13863" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "P13863", "database": "UniProtKB", "url": 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"evidence": [ { "id": "P21868", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P21868" } ] } ] }, { "uniprot_ac": "P21869", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P21869", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P21869" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P21869", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P21869" } ] } ] }, { "uniprot_ac": "P53666", "gene_name": "LIMK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P53666", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P53666" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P53666", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P53666" } ] } ] }, { "uniprot_ac": "P67962", "gene_name": "CSNK1A1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P67962", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P67962" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P67962", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P67962" } ] } ] }, { "uniprot_ac": "P79996", "gene_name": "MAPK9", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P79996", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P79996" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "P79996", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P79996" } ] } ] }, { "uniprot_ac": "Q04982", "gene_name": "BRAF", "activity": [ { "ec_number": "2.7.11.1", 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"ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "Q5ZIU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZIU3" } ] } ] }, { "uniprot_ac": "Q5ZJH6", "gene_name": "ULK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5ZJH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJH6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q5ZJH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJH6" } ] } ] }, { "uniprot_ac": "Q5ZJK4", "gene_name": "STK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5ZJK4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJK4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q5ZJK4", "database": "UniProtKB", "url": 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"id": "A0A8V0YA03-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YA03-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YF63", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF63", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YF63-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF63-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YGA8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGA8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YGA8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGA8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YN52", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN52", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YN52-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN52-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLLMSHRGGHQESKKKLEISPSETMKAEEENYKEEAKEPKSEDWRPPSVFGAADLKNRAVGLYNIGQTCCLNSLLQVFLMNIHFTKILRRISVPVCATQKKKNVPYQMLLLLEKMQCGKQKAVSPRELVLCLEAHRVTMFVQYDAAQLFLTLWNLLKKQMKNPELVEKLSDLYTISVQEHLACQICSSETKRNSSMLSLPVPLLDSDSSMLKTLEKCLQCFFRPEELTGHNMCFCEHCGKKTPFQQSVKLVHLPQTLTIHLKRFCFGRSAYIHKISNCLPFPQDLDFNAVLTEQQCQAYDNEKAAWRYELFAVVAHSGTTSYGHYCAYIRSLTECKWYCFNDSFVEQVSWDDVKSTYGHSDLYWVAAYKTVWET", "length": 374, "header": "tr|A0A8V0YGA8-1|A0A8V0YGA8_CHICK Isoform 1 of Ubiquitin specific peptidase 18 OS=Gallus gallus OX=9031 GN=USP41 PE=4 SV=1 CANONICAL=A0A8V0YGA8-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Y9Z9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGA8/entry#A0A8V0Y9Z9-1", "sequence": { "sequence": "MQPVNPLVSSAHKDALLLWMGFQNPECLVKPLSRRHTDPSVIVHAMLLMSHRGGHQESKKKLEISPSETMKAEEENYKEEAKEPKSEDWRPPSVFGAADLKNRAVGLYNIGQTCCLNSLLQVFLMNIHFTKILRRISVPVCATQKKKNVPYQMLLLLEKMQCGKQKAVSPRELVLCLEAHRVTMFVQYDAAQLFLTLWNLLKKQMKNPELVEKLSDLYTISVQEHLACQICSSETKRNSSMLSLPVPLLDSDSSMLKTLEKCLQCFFRPEELTGHNMCFCEHCGKKTPFQQSVKLVHLPQTLTIHLKRFCFGRSAYIHKISNCLPFPQDLDFNAVLTEQQCQAYDNEKAAWRYELFAVVAHSGTTSYGHYCAYIRSLTECKWYCFNDSFVEQVSWDDVKSTYGHSDLYWGQTAYLLFYMKKQPQ", "length": 424, "header": "tr|A0A8V0Y9Z9-1|A0A8V0Y9Z9_CHICK Computationally mapped isoform of Ubiquitin carboxyl-terminal hydrolase OS=Gallus gallus OX=9031 GN=USP41 PE=3 SV=1 CANONICAL=A0A8V0YGA8-1" }, "locus": { "chromosome": "1", "start_pos": 62141432, "end_pos": 62130418, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030241.1", "url": "https://www.ensembl.org/id/ENSGALT00010030241.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017548.1", "url": "https://www.ensembl.org/id/ENSGALP00010017548.1" } ] } }, { "isoform_ac": "A0A8V0YA03-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGA8/entry#A0A8V0YA03-1", "sequence": { "sequence": "MLLMSHRGGHQESKKKLEISPSETMKAEEENYKEEAKEPKSEDWRPPSVFGAADLKNRAVGLYNIGQTCCLNSLLQVFLMNIHFTKILRRISVPVCATQKKKNVPYQMLLLLEKMQCGKQKAVSPRELVLCLEAHRVTMFVQYDAAQLFLTLWNLLKKQMKNPELVEKLSDLYTISVQEHLACQICSSETKRNSSMLSLPVPLLDSDSSMLKTLEKCLQCFFRPEELTGHNMCFCEHCGKKTPFQQSVKLVHLPQTLTIHLKRFCFGRSAYIHKISNCLPFPQDLDFNAVLTEQQCQAYDNEKAAWRYELFAVVAHSGTTSYGHYCAYIRSLTECKWYCFNDSFVEQVSWDDVKSTYGHSDLYWGQTAYLLFYMKKQPQ", "length": 379, "header": "tr|A0A8V0YA03-1|A0A8V0YA03_CHICK Computationally mapped isoform of Ubiquitin specific peptidase 18 OS=Gallus gallus OX=9031 GN=USP41 PE=4 SV=1 CANONICAL=A0A8V0YGA8-1" }, "locus": { "chromosome": "1", "start_pos": 62141432, "end_pos": 62131462, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030256.1", "url": "https://www.ensembl.org/id/ENSGALT00010030256.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017553.1", "url": "https://www.ensembl.org/id/ENSGALP00010017553.1" } ] } }, { "isoform_ac": "A0A8V0YF63-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGA8/entry#A0A8V0YF63-1", "sequence": { "sequence": "MLLMSHRGGHQESKKKLEISPSETMKAEEENYKEEAKEPKSEDWRPPSVFGAADLKNRAVGLYNIGQTCCLNSLLQVFLMNIHFTKILRRISVPVCATQKKKNVPYQMLLLLEKMQCGKQKAVSPRELVLCLEAHRVTMFVQYDAAQLFLTLWNLLKKQMKNPELVEKLSDLYTISVQEHLACQICSSETKRNSSMLSLPVPLLDSDSSMLKTLSVKLVHLPQTLTIHLKRFCFGRSAYIHKISNCLPFPQDLDFNAVLTEQQCQAYDNEKAAWRYELFAVVAHSGTTSYGHYCAYIRSLTECKWYCFNDSFVEQVSWDDVKSTYGHSDLYWGQTAYLLFYMKKQPQ", "length": 347, "header": "tr|A0A8V0YF63-1|A0A8V0YF63_CHICK Computationally mapped isoform of Ubiquitin specific peptidase 18 OS=Gallus gallus OX=9031 GN=USP41 PE=4 SV=1 CANONICAL=A0A8V0YGA8-1" }, "locus": { "chromosome": "1", "start_pos": 62141432, "end_pos": 62131462, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030253.1", "url": "https://www.ensembl.org/id/ENSGALT00010030253.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017552.1", "url": "https://www.ensembl.org/id/ENSGALP00010017552.1" } ] } }, { "isoform_ac": "A0A8V0YGA8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGA8/entry#A0A8V0YGA8-1", "sequence": { "sequence": "MLLMSHRGGHQESKKKLEISPSETMKAEEENYKEEAKEPKSEDWRPPSVFGAADLKNRAVGLYNIGQTCCLNSLLQVFLMNIHFTKILRRISVPVCATQKKKNVPYQMLLLLEKMQCGKQKAVSPRELVLCLEAHRVTMFVQYDAAQLFLTLWNLLKKQMKNPELVEKLSDLYTISVQEHLACQICSSETKRNSSMLSLPVPLLDSDSSMLKTLEKCLQCFFRPEELTGHNMCFCEHCGKKTPFQQSVKLVHLPQTLTIHLKRFCFGRSAYIHKISNCLPFPQDLDFNAVLTEQQCQAYDNEKAAWRYELFAVVAHSGTTSYGHYCAYIRSLTECKWYCFNDSFVEQVSWDDVKSTYGHSDLYWVAAYKTVWET", "length": 374, "header": "tr|A0A8V0YGA8-1|A0A8V0YGA8_CHICK Isoform 1 of Ubiquitin specific peptidase 18 OS=Gallus gallus OX=9031 GN=USP41 PE=4 SV=1 CANONICAL=A0A8V0YGA8-1" }, "locus": { "chromosome": "1", "start_pos": 62144131, "end_pos": 62131462, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030261.1", "url": "https://www.ensembl.org/id/ENSGALT00010030261.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017555.1", "url": "https://www.ensembl.org/id/ENSGALP00010017555.1" } ] } }, { "isoform_ac": "A0A8V0YN52-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGA8/entry#A0A8V0YN52-1", "sequence": { "sequence": "MRPRGKAEVNPLVSSAHKDALLLWMGFQNPECLVKPLSRRHTDPSVIVHAMLLMSHRGGHQESKKKLEISPSETMKAEEENYKEEAKEPKSEDWRPPSVFGAADLKNRAVGLYNIGQTCCLNSLLQVFLMNIHFTKILRRISVPVCATQKKKNVPYQMLLLLEKMQCGKQKAVSPRELVLCLEAHRVTMFVQYDAAQLFLTLWNLLKKQMKNPELVEKLSDLYTISVQEHLACQICSSETKRNSSMLSLPVPLLDSDSSMLKTLEKCLQCFFRPEELTGHNMCFCEHCGKKTPFQQSVKLVHLPQTLTIHLKRFCFGRSAYIHKISNCLPFPQDLDFNAVLTEQQCQAYDNEKAAWRYELFAVVAHSGTTSYGHYCAYIRSLTECKWYCFNDSFVEQVSWDDVKSTYGHSDLYWGQTAYLLFYMKKQPQ", "length": 429, "header": "tr|A0A8V0YN52-1|A0A8V0YN52_CHICK Computationally mapped isoform of Ubiquitin carboxyl-terminal hydrolase OS=Gallus gallus OX=9031 GN=USP41 PE=3 SV=1 CANONICAL=A0A8V0YGA8-1" }, "locus": { "chromosome": "1", "start_pos": 62141432, "end_pos": 62128886, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030245.1", "url": "https://www.ensembl.org/id/ENSGALT00010030245.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017549.1", "url": "https://www.ensembl.org/id/ENSGALP00010017549.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "R-GGA-5689880", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5689880", "resource": "Reactome", "description": "Ub-specific processing proteases" }, { "id": "R-GGA-912694", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-912694", "resource": "Reactome", "description": "Regulation of IFNA/IFNB signaling" }, { "id": "R-GGA-9758274", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9758274", "resource": "Reactome", "description": "Regulation of NF-kappa B signaling" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287A210-1", "protein_name": "Ubl carboxyl-terminal hydrolase 18", "gene_name": "USP18", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGPVGLHNIGQTCCLNSLIQVLIMNVGLTKILKRMTVPRGAEEQRRNVPFQLLLLLEKMQDSRQKAVQPMELAYCLQKYNIPMFVQHDAAQLYLTVWNLIKDQITDVDLVARLQALYTIRVKETFVCLECTTEHVRNSSMLTLPLSLFDMDSKPLKTLEDALHCFFQPRELSGRDKCFCENCGRKTCWKQVLKLSRLPQTLTLHLMRFSIKNLRTEKVCHSLYFPQSLDLNPLLETEEEPCAAEGQPGGRYELFAVIAHMGLADFGHYCAYVRSAADGKWFCFNDSNVCWVSWEDIQCTYGNHSFRWRETAYLLVYMMAES", "length": 321 }, "evidence": [ { "id": "A0A8V0YGA8", "url": "https://omabrowser.org/oma/group/A0A8V0YGA8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q9UMW8-1", "protein_name": "Ubl carboxyl-terminal hydrolase 18", "gene_name": "USP18", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSKAFGLLRQICQSILAESSQSPADLEEKKEEDSNMKREQPRERPRAWDYPHGLVGLHNIGQTCCLNSLIQVFVMNVDFTRILKRITVPRGADEQRRSVPFQMLLLLEKMQDSRQKAVRPLELAYCLQKCNVPLFVQHDAAQLYLKLWNLIKDQITDVHLVERLQALYTIRVKDSLICVDCAMESSRNSSMLTLPLSLFDVDSKPLKTLEDALHCFFQPRELSSKSKCFCENCGKKTRGKQVLKLTHLPQTLTIHLMRFSIRNSQTRKICHSLYFPQSLDFSQILPMKRESCDAEEQSGGQYELFAVIAHVGMADSGHYCVYIRNAVDGKWFCFNDSNICLVSWEDIQCTYGNPNYHWQETAYLLVYMKMEC", "length": 372 }, "evidence": [ { "id": "A0A8V0YGA8", "url": "https://omabrowser.org/oma/group/A0A8V0YGA8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9WTV6-1", "protein_name": "Ubl carboxyl-terminal hydrolase 18", "gene_name": "Usp18", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGKGFGLLRKPCQSVVAEPQQYSALEEERTMKRKRVLSRDLCSAWDSPHGLVGLHNIGQTCCLNSLLQVFMMNMDFRMILKRITVPRSAEERKRSVPFQLLLLLEKMQDSRQKAVLPTELVQCLQKYNVPLFVQHDAAQLYLTIWNLTKDQITDTDLTERLQGLFTIWTQESLICVGCTAESSRRSKLLTLSLPLFDKDAKPLKTLEDALRCFVQPKELASSDMCCESCGEKTPWKQVLKLTHLPQTLTIHLMRFSARNSRTEKICHSVNFPQSLDFSQVLPTEEDLGDTKEQSEIHYELFAVIAHVGMADFGHYCAYIRNPVDGKWFCFNDSHVCWVTWKDVQCTYGNHRYRWRETAYLLVYTKTGS", "length": 368 }, "evidence": [ { "id": "A0A8V0YGA8", "url": "https://omabrowser.org/oma/group/A0A8V0YGA8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 7, "go_terms": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGA8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGA8" } ], "pmid": "" }, { "name": "protein deubiquitination", "id": "GO:0016579", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016579", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGA8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGA8" } ], "pmid": "" }, { "name": "regulation of protein stability", "id": "GO:0031647", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031647", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGA8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGA8" } ], "pmid": "" }, { "name": "regulation of inflammatory response", "id": "GO:0050727", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050727", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGA8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGA8" } ], "pmid": "" }, { "name": "response to stilbenoid", "id": "GO:0035634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGA8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGA8" } ], "pmid": "" }, { "name": "negative regulation of type I interferon-mediated signaling pathway", "id": "GO:0060339", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060339", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGA8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGA8" } ], "pmid": "" }, { "name": "antiviral innate immune response", "id": "GO:0140374", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140374", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGA8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGA8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "cysteine-type deubiquitinase activity", "id": "GO:0004843", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004843", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGA8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGA8" } ], "pmid": "" }, { "name": "molecular adaptor activity", "id": "GO:0060090", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060090", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGA8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGA8" } ], "pmid": "" }, { "name": "ISG15-specific peptidase activity", "id": "GO:0019785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019785", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGA8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGA8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGA8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGA8" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGA8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGA8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 193, "end_pos": 195, "annotation": "n_glycosylation_sequon" }, { "start_pos": 341, "end_pos": 343, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-GGA-5696534", "name": "USP18 deubiquitinates TAK1:TAB1", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XCV5-1", "A0A8V0YGA8-1" ], "evidence": [ { "id": "R-GGA-5696534", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5696534" } ] }, { "id": "R-GGA-912685", "name": "UBP43 binds IFNAR2 and prevents JAK1 interaction", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YGA8-1" ], "evidence": [ { "id": "R-GGA-912685", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-912685" } ] }, { "id": "R-GGA-9761344", "name": "USP18 binds IKBKG within IKK complex", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YXK2-1", "A0A8V0XYS4-1", "A0A8V0YGA8-1" ], "evidence": [ { "id": "R-GGA-9761344", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9761344" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A8V0XCV5", "gene_name": "MAP3K7", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XCV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCV5" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0XCV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCV5" } ] } ] }, { "uniprot_ac": "A0A8V0XYS4", "gene_name": "CWF19L1", "activity": [ { "ec_number": "2.7.11.10", "activity": "L-seryl-[I-kappa-B protein] + ATP = O-phospho-L-seryl-[I-kappa-B protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XYS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XYS4" } ] }, { "ec_number": "2.7.11.10", "activity": "", "evidence": [ { "id": "A0A8V0XYS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XYS4" } ] } ] }, { "uniprot_ac": "A0A8V0YGA8", "gene_name": "USP41", "activity": [ { "ec_number": "3.4.19.12", "activity": "Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).", "evidence": [ { "id": "A0A8V0YGA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGA8" } ] }, { "ec_number": "3.4.19.12", "activity": "", "evidence": [ { "id": "A0A8V0YGA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGA8" } ] } ] }, { 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Peptide", "id": "ENSGALP00010016789.1", "url": "https://www.ensembl.org/id/ENSGALP00010016789.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "clathrin-coated pit", "id": "GO:0005905", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005905", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YL44", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL44" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "endocytosis", "id": "GO:0006897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006897", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YL44", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL44" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 126, "end_pos": 128, "annotation": "n_glycosylation_sequon" }, { 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{ "id": "PF06201", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06201", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YD00", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD00", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YD00-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD00-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YD05", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD05", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YD05-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD05-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJA9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJA9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJA9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJA9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJC5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJC5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJC5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJC5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJD0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJD0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJD0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJD0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YL97", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL97", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YL97-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL97-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRMVGVKLIVNDTEFQPELSAVGSRLAVVKFTMRGCGPCLRIAPAFSALSNKYLQAMFLEVDVHQCQGTAATNNISATPTFLFFRNKVRIDHYQGADVVGLEEKIKQHLENDPGNNEDTDIPKGYKNENLMDLMAFINKAGCECLNESDEHGFDNCLRKDSTFLESDCDEQLLITVAFSQPVKLYSMKLQGPDNGQGPKYIKIFINLPRSMDFEEAETSEPTQALELTPDDIKEDGIVQLRYVKFQNVNCVTLFVQSNHGDEEATRITYLTFIGTPVQATNMNDFKRVVGKKGESH", "length": 296, "header": "tr|A0A8V0YJC5-1|A0A8V0YJC5_CHICK Isoform 1 of PITH domain-containing protein OS=Gallus gallus OX=9031 GN=LOC107049459 PE=4 SV=1 CANONICAL=A0A8V0YJC5-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YD00-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJC5/entry#A0A8V0YD00-1", "sequence": { "sequence": "MRMVGVKLIVNDTEFQPELSAVGSRLAVVKFTMRGCGPCLRIAPAFSALSNKYLQAMFLEVDVHQCQGTAATNNISATPTFLFFRNKVRIDHYQGADVVGLEEKIKQHLENDPGNNEDTDIPKGYMDLMAFINKAGCECLNESDEHGFDNCLRKDSTFLESDCDEQLLITVAFSQPVKLYSMKLQGPDNGQGPKYIKIFINLPRSMDFEEAETSEPTQALELTPDDIKEDGIVQLRYVKFQNVNCVTLFVQSNHGDEEATRITYLTFIGTPVQATNMNDFKRVR", "length": 284, "header": "tr|A0A8V0YD00-1|A0A8V0YJC5_CHICK Computationally mapped isoform of PITH domain-containing protein OS=Gallus gallus OX=9031 GN=LOC107049459 PE=4 SV=1 CANONICAL=A0A8V0YJC5-1" }, "locus": { "chromosome": "W", "start_pos": 8183329, "end_pos": 8161299, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031863.1", "url": "https://www.ensembl.org/id/ENSGALT00010031863.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018667.1", "url": "https://www.ensembl.org/id/ENSGALP00010018667.1" } ] } }, { "isoform_ac": "A0A8V0YD05-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJC5/entry#A0A8V0YD05-1", "sequence": { "sequence": "MTSSECGPCLRIAPAFSALSNKYLQAMFLEVDVHQCQGTAATNNISATPTFLFFRNKVRIDHYQGADVVGLEEKIKQHLENDPGNNEDTDIPKGYMDLMAFINKAGCECLNESDEHGFDNCLRKDSTFLESDCDEQLLITVAFSQPVKLYSMKLQGPDNGQGPKYIKIFINLPRSMDFEEAETSEPTQALELTPDDIKEDGIVQLRYVKFQNVNCVTLFVQSNHGDEEATRITYLTFIGTPVQATNMNDFKRVVGKKGESH", "length": 261, "header": "tr|A0A8V0YD05-1|A0A8V0YJC5_CHICK Computationally mapped isoform of PITH domain-containing protein OS=Gallus gallus OX=9031 GN=LOC107049459 PE=4 SV=1 CANONICAL=A0A8V0YJC5-1" }, "locus": { "chromosome": "W", "start_pos": 8260824, "end_pos": 8137842, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031869.1", "url": "https://www.ensembl.org/id/ENSGALT00010031869.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018672.1", "url": "https://www.ensembl.org/id/ENSGALP00010018672.1" } ] } }, { "isoform_ac": "A0A8V0YJA9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJC5/entry#A0A8V0YJA9-1", "sequence": { "sequence": "MRMVGVKLIVNDTEFQPELSAVGSRLAVVKFTMRGCGPCLRIAPAFSALSNKYLQAMFLEVDVHQCQGTAATNNISATPTFLFFRNKVRIDHYQGADVVGLEEKIKQHLENDPGNNEDTDIPKGYMDLMAFINKAGCECLNESDEHGFDNCLRKDSTFLESDCDEQLLITVAFSQPVKLYSMKLQGPDNGQGPKYIKIFINLPRSMDFEEAETSEPTQALELTPDDIKEDGIVQLRYVKFQNVNCVTVKPQDGTWHAPAIYSQAEESLLLMEEILVCTDGG", "length": 281, "header": "tr|A0A8V0YJA9-1|A0A8V0YJA9_CHICK Computationally mapped isoform of PITH domain-containing protein OS=Gallus gallus OX=9031 GN=LOC107049459 PE=4 SV=1 CANONICAL=A0A8V0YJC5-1" }, "locus": { "chromosome": "W", "start_pos": 8183329, "end_pos": 8170763, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031845.1", "url": "https://www.ensembl.org/id/ENSGALT00010031845.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018649.1", "url": "https://www.ensembl.org/id/ENSGALP00010018649.1" } ] } }, { "isoform_ac": "A0A8V0YJC5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJC5/entry#A0A8V0YJC5-1", "sequence": { "sequence": "MRMVGVKLIVNDTEFQPELSAVGSRLAVVKFTMRGCGPCLRIAPAFSALSNKYLQAMFLEVDVHQCQGTAATNNISATPTFLFFRNKVRIDHYQGADVVGLEEKIKQHLENDPGNNEDTDIPKGYKNENLMDLMAFINKAGCECLNESDEHGFDNCLRKDSTFLESDCDEQLLITVAFSQPVKLYSMKLQGPDNGQGPKYIKIFINLPRSMDFEEAETSEPTQALELTPDDIKEDGIVQLRYVKFQNVNCVTLFVQSNHGDEEATRITYLTFIGTPVQATNMNDFKRVVGKKGESH", "length": 296, "header": "tr|A0A8V0YJC5-1|A0A8V0YJC5_CHICK Isoform 1 of PITH domain-containing protein OS=Gallus gallus OX=9031 GN=LOC107049459 PE=4 SV=1 CANONICAL=A0A8V0YJC5-1" }, "locus": { "chromosome": "W", "start_pos": 8183329, "end_pos": 8137842, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031860.1", "url": "https://www.ensembl.org/id/ENSGALT00010031860.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018664.1", "url": "https://www.ensembl.org/id/ENSGALP00010018664.1" } ] } }, { "isoform_ac": "A0A8V0YJD0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJC5/entry#A0A8V0YJD0-1", "sequence": { "sequence": "MRMVGVKLIVNDTEFQPELSAVGSRLAVVKFTMRGCGPCLRIAPAFSALSNKYLQAMFLEVDVHQCQGTAATNNISATPTFLFFRNKVRIDHYQGADVVGLEEKIKQHLENDPGNNEDTDIPKGYMDLMAFINKAGCECLNESDEHGFDNCLRKDSTFLESDCDEQLLITVAFSQPVKLYSMKLQGPDNGQGPKYIKIFINLPRSMDFEEAETSEPTQALELTPDDIKEDGIVQLRYVKFQNVNCVTLFVQSNHGDEEATRITYLTFIGTPVQATNMNDFKRVVGKKGESH", "length": 291, "header": "tr|A0A8V0YJD0-1|A0A8V0YJD0_CHICK Computationally mapped isoform of PITH domain-containing protein OS=Gallus gallus OX=9031 GN=LOC107049459 PE=4 SV=1 CANONICAL=A0A8V0YJC5-1" }, "locus": { "chromosome": "W", "start_pos": 8183329, "end_pos": 8137842, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031865.1", "url": "https://www.ensembl.org/id/ENSGALT00010031865.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018669.1", "url": "https://www.ensembl.org/id/ENSGALP00010018669.1" } ] } }, { "isoform_ac": "A0A8V0YL97-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJC5/entry#A0A8V0YL97-1", "sequence": { "sequence": "MRMVGVKLIVNDTEFQPELSAVGSRLAVVKFTMRGCGPCLRIAPAFSALSNKYLQAMFLEVDVHQCQGTAATNNISATPTFLFFRNKVRIDHYQGADVVGLEEKIKQHLENDPGNNEDTDIPKGYMDLMAFINKAGCECLNESDEHGFDNCLRKDSTFLESDCDEQLLITVAFSQPVKLYSMKLQGPDNGQGPKYIKIFINLPRSMDFEEAETSEPTQALELTPDDIKEDGIVQLRYVKFQNVNCVTLIPSSTEYLSPWWFICLGYIPGLP", "length": 271, "header": "tr|A0A8V0YL97-1|A0A8V0YL97_CHICK Computationally mapped isoform of PITH domain-containing protein OS=Gallus gallus OX=9031 GN=LOC107049459 PE=4 SV=1 CANONICAL=A0A8V0YJC5-1" }, "locus": { "chromosome": "W", "start_pos": 8183329, "end_pos": 8169347, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031851.1", "url": "https://www.ensembl.org/id/ENSGALT00010031851.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018655.1", "url": "https://www.ensembl.org/id/ENSGALP00010018655.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJC5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJC5" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJC5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJC5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "protein-disulfide reductase activity", "id": "GO:0015035", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015035", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJC5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJC5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 11, "end_pos": 13, "annotation": "n_glycosylation_sequon" }, { "start_pos": 146, "end_pos": 148, "annotation": "n_glycosylation_sequon" }, { "start_pos": 74, "end_pos": 76, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YJC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJC5" }, { "id": "PS51532", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51532" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PITH", "eco_id": "ECO_0000259", "start_pos": 122, "end_pos": 292, "start_aa": "Pro", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 11, "end_pos": 13 }, { "start_pos": 146, "end_pos": 148 }, { "start_pos": 74, "end_pos": 76 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YL98-1", "uniprot_ac": "A0A8V0YL98", "uniprot_id": "A0A8V0YL98_CHICK", "mass": { "chemical_mass": 109583.0, "monoisotopic_mass": 109583.0 }, "refseq": { "ac": "XP_040521130", "name": "meckelin isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040521130" }, "gene_names": [ { "name": "TMEM67", "type": "recommended", "evidence": [ { "id": "A0A8V0YL98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL98" } ] }, { "name": "TMEM67", "type": "synonym", "evidence": [ { "id": "XP_040521130", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040521130" } ] } ], "protein_names": [ { "name": "Transmembrane protein 67", "type": "synonym", "evidence": [ { "id": "A0A8V0YL98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL98/entry#names_and_taxonomy" } ] }, { "name": "meckelin isoform X1", "type": "synonym", "evidence": [ { "id": "XP_040521130", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040521130" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052574.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040521130", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040521130" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YL98", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL98" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TMEM67", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL98", "locus": { "chromosome": "2", "start_pos": 125476364, "end_pos": 125445874, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012130", "url": "https://www.ensembl.org/id/ENSGALG00010012130" } ] } } ], "crossref": [ { "id": "A0A8V0YL98", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YL98", "database": "AlphaFoldDB", "categories": [] }, { "id": "420224", "url": "https://www.ncbi.nlm.nih.gov/gene/420224", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR009030", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009030", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019170", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019170", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:420224", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420224", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YITENKG", "url": "https://omabrowser.org/oma/group/YITENKG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YD28", "url": "https://www.orthodb.org/?gene=A0A8V0YD28", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YGI2", "url": "https://www.orthodb.org/?gene=A0A8V0YGI2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YL98", "url": "https://www.orthodb.org/?gene=A0A8V0YL98", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21274", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21274", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21274:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21274:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF09773", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09773", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-5620912", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5620912", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_040521130", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040521130", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YD28", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD28", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YD28-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD28-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YGI2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGI2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YGI2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGI2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YL98", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL98", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YL98-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL98-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MATAAALLLLFWISPSARGFSLPLQRPGDCGDERYFDISRLSCGPCGAHQRRSASGSSCVCLPGYRMVSNNGGSSVICEKCPENMSGVTQDGWNCITCPKGMTSEGKCKCLSNEILVERGVDGVLLNEALCIVCNGSPQSFSASDVLGSRCVRCEQTFINVSMSCDCSSPNILSGGLCFSARESLPPKGIATVRFGQVGVTLTSAWFLKNLEASASACWLYSNLTACQALGNMCVMNMNSLSSSSTDACSLFQYIYANTARLGIVHSIAFWRHNLPWLYYGDQPGLASKVLETNHLPTIFSFKGRSEDVKLQFIAASYDAAGNFLKWQSLEGGLLQLCPDTQNKLNAAYVFGTTYEQSCKISIAKILLDFSNPVFYDLFFEYNGDNGQQYLWAVPVLNLNLQYSEMYVNQGSNMNNWLLTRRFFLVDTLSGRENDLGKLPRIIRVASKITISIRLVSHTQKGTIYPPLITVAYTDVLVQNPDTQSVMVSFSVRYEMNQSEAQIQTDITLGVLGGLAVLWSLLRTAGWKRRTGSSVIDLQTVFKFFLFYAGDLANVFFIITVGTGIYWLVFFKAQQFVSVLLPLPSQEKAFVTYVACAFSLKALQFLQLLVSQLTVDIFFIDWERPKGRVLKAVEGEGDVKSAAAPVSIWRTYFIANEWNEMQTVRKINPLFQVLAVLFFLEVVGFSNLALMDSSSSLTRSSESYIAPWSRILRFGVSVALWLAIAFLQIIFFAVFYERFVEDKLSQFVDLCCVSNISVFLLSHSCFGYYIHGRSVHGHADTNMEEMNMNLKREAENLCSQRGLLPNTDGQTFQISISRKMRLQYDRIHETLTRRRGPARFLDSSANTFEQSTRAYNTMNKFLSSFIDHVHKDMDYIVKDKLLLERILGMEFMEPIEKSIFYNDEGHSFSEVLYYGNETTLLIFDILFFSVVDLATQSFVLAAILTYLQQEIFRFIRNKVGRKNLTSKTLVDERFLI", "length": 976, "header": "tr|A0A8V0YL98-1|A0A8V0YL98_CHICK Isoform 1 of Transmembrane protein 67 OS=Gallus gallus OX=9031 GN=TMEM67 PE=4 SV=1 CANONICAL=A0A8V0YL98-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YD28-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL98/entry#A0A8V0YD28-1", "sequence": { "sequence": "MATAAALLLLFWISPSARGFSLPLQRPGDCGDERYFDISRLSCGPCGAHQRRSASGSSCVCLPGYRMVSNNGGSSVICEKCPENMSGVTQDGWNCITCPKGMTSEGKCKCLSNEILVERGVDGVLLNEALCIVCNGSPQSFSASDVLGSRCVRCEQTFINVSMSCDCSSPNILVSRGTLIALKFRKMKSCVEKYKCFHFKISFLFQSGGLCFSARESLPPKGIATVRFGQVGVTLTSAWFLKNLEASASACWLYSNLTACQALGNMCVMNMNSLSSSSTDACSLFQYIYANTARLGIVHSIAFWRHNLPWLYYGDQPGLASKVLETNHLPTIFSFKGRSEDVKLQFIAASYDAAGNFLKWQSLEGGLLQLCPDTQNKLNAAYVFGTTYEQSCKISIAKILLDFSNPVFYDLFFEYNGDNGQQYLWAVPVLNLNLQYSEMYVNQGSNMNNWLLTRRFFLVDTLSGRENDLGKLPRIIRVASKITISIRLVSHTQKGTIYPPLITVAYTDVLVQNPDTQSVMVSFSVRYEMNQSEAQIQTDITLGVLGGLAVLWSLLRTAGWKRRTGSSVIDLQTVFKFFLFYAGDLANVFFIITVGTGIYWLVFFKAQQFVSVLLPLPSQEKAFVTYVACAFSLKALQFLQLLVSQLTVDIFFIDWERPKGRVLKAVEGEGDVKSAAAPVSIWRTYFIANEWNEMQTVRKINPLFQVLAVLFFLEVVGFSNLALMDSSSSLTRSSESYIAPWSRILRFGVSVALWLAIAFLQIIFFAVFYERFVEDKLSQFVDLCCVSNISVFLLSHSCFGYYIHGRSVHGHADTNMEEMNMNLKREAENLCSQRGLLPNTDGQTFQISISRKMRLQYDRIHETLTRRRGPARFLDSSANTFEQSTRAYNTMNKFLSSFIDHVHKDMDYIVKDKLLLERILGMEFMEPIEKSIFYNDF", "length": 937, "header": "tr|A0A8V0YD28-1|A0A8V0YL98_CHICK Computationally mapped isoform of Transmembrane protein 67 OS=Gallus gallus OX=9031 GN=TMEM67 PE=4 SV=1 CANONICAL=A0A8V0YL98-1" }, "locus": { "chromosome": "2", "start_pos": 125474248, "end_pos": 125445911, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029096.1", "url": "https://www.ensembl.org/id/ENSGALT00010029096.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016855.1", "url": "https://www.ensembl.org/id/ENSGALP00010016855.1" } ] } }, { "isoform_ac": "A0A8V0YGI2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL98/entry#A0A8V0YGI2-1", "sequence": { "sequence": "MATAAALLLLFWISPSARGFSLPLQRPGDCGDERYFDISRLSCGPCGAHQRRSASGSSCVCLPGYRMVSNNGGSSVICEKCPENMSGVTQDGWNCITCPKGMTSEGKCKCLSNEILVERGVDGVLLNEALCIVCNGSPQSFSASDVLGSRCVRCEQTFINVSMSCDCSSPNILSGGLCFSARESLPPKGIATVRFGQVGVTLTSAWFLKNLEASASACWLYSNLTACQALGNMCVMNMNSLSSSSTDACSLFQYIYANTARLGIVHSIAFWRHNLPWLYYGDQPGLASKVLETNHLPTIFSFKGRSEDVKLQFIAASYDAAGNFLKWQSLEGGLLQLCPDTQNKLNAAYVFGTTYEQSCKISIAKILLDFSNPVFYDLFFEYNGDNGQQYLWAVPVLNLNLQYSEMYVNQGSNMNNWLLTRRFFLVDTLSGRENDLGKLPRIIRVASKITISIRLVSHTQKGTIYPPLITVAYTDVLVQNPDTQSVMVSFSVRYEMNQSEAQIQTDITLGVLGGLAVLWSLLRTAGWKRRTGSSVIDLQTVFKFFLFYAGDLANVFFIITVGTGIYWLVFFKAQQFVSVLLPLPSQEKAFVTYVACAFSLKALQFLQLLVSQLTVDIFFIDWERPKGRVLKAVEGEGDVKSAAAPVSIWRTYFIANEWNEMQTVRKINPLFQVLAVLFFLEVVGFSNLALMDSSSSLTRSSESYIAPWSRILRFGVSVALWLAIAFLQISVFLLSHSCFGYYIHGRSVHGHADTNMEEMNMNLKREAENLCSQRGLLPNTDGQTFQISISRKMRLQYDRIHETLTRRRGPARFLDSSANTFEQSTRAYNTMNKFLSSFIDHVHKDMDYIVKDKLLLERILGMEFMEPIEKSIFYNDEGHSFSEVLYYGNETTLLIFDILFFSVVDLATQSFVLAAILTYLQQEIFRFIRNKVGRKNLTSKTLVDERFLI", "length": 949, "header": "tr|A0A8V0YGI2-1|A0A8V0YL98_CHICK Computationally mapped isoform of Transmembrane protein 67 OS=Gallus gallus OX=9031 GN=TMEM67 PE=4 SV=1 CANONICAL=A0A8V0YL98-1" }, "locus": { "chromosome": "2", "start_pos": 125474321, "end_pos": 125445911, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029102.1", "url": "https://www.ensembl.org/id/ENSGALT00010029102.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016861.1", "url": "https://www.ensembl.org/id/ENSGALP00010016861.1" } ] } }, { "isoform_ac": "A0A8V0YL98-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL98/entry#A0A8V0YL98-1", "sequence": { "sequence": "MATAAALLLLFWISPSARGFSLPLQRPGDCGDERYFDISRLSCGPCGAHQRRSASGSSCVCLPGYRMVSNNGGSSVICEKCPENMSGVTQDGWNCITCPKGMTSEGKCKCLSNEILVERGVDGVLLNEALCIVCNGSPQSFSASDVLGSRCVRCEQTFINVSMSCDCSSPNILSGGLCFSARESLPPKGIATVRFGQVGVTLTSAWFLKNLEASASACWLYSNLTACQALGNMCVMNMNSLSSSSTDACSLFQYIYANTARLGIVHSIAFWRHNLPWLYYGDQPGLASKVLETNHLPTIFSFKGRSEDVKLQFIAASYDAAGNFLKWQSLEGGLLQLCPDTQNKLNAAYVFGTTYEQSCKISIAKILLDFSNPVFYDLFFEYNGDNGQQYLWAVPVLNLNLQYSEMYVNQGSNMNNWLLTRRFFLVDTLSGRENDLGKLPRIIRVASKITISIRLVSHTQKGTIYPPLITVAYTDVLVQNPDTQSVMVSFSVRYEMNQSEAQIQTDITLGVLGGLAVLWSLLRTAGWKRRTGSSVIDLQTVFKFFLFYAGDLANVFFIITVGTGIYWLVFFKAQQFVSVLLPLPSQEKAFVTYVACAFSLKALQFLQLLVSQLTVDIFFIDWERPKGRVLKAVEGEGDVKSAAAPVSIWRTYFIANEWNEMQTVRKINPLFQVLAVLFFLEVVGFSNLALMDSSSSLTRSSESYIAPWSRILRFGVSVALWLAIAFLQIIFFAVFYERFVEDKLSQFVDLCCVSNISVFLLSHSCFGYYIHGRSVHGHADTNMEEMNMNLKREAENLCSQRGLLPNTDGQTFQISISRKMRLQYDRIHETLTRRRGPARFLDSSANTFEQSTRAYNTMNKFLSSFIDHVHKDMDYIVKDKLLLERILGMEFMEPIEKSIFYNDEGHSFSEVLYYGNETTLLIFDILFFSVVDLATQSFVLAAILTYLQQEIFRFIRNKVGRKNLTSKTLVDERFLI", "length": 976, "header": "tr|A0A8V0YL98-1|A0A8V0YL98_CHICK Isoform 1 of Transmembrane protein 67 OS=Gallus gallus OX=9031 GN=TMEM67 PE=4 SV=1 CANONICAL=A0A8V0YL98-1" }, "locus": { "chromosome": "2", "start_pos": 125474321, "end_pos": 125445911, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029100.1", "url": "https://www.ensembl.org/id/ENSGALT00010029100.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016859.1", "url": "https://www.ensembl.org/id/ENSGALP00010016859.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:420224", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420224", "resource": "KEGG Pathway" }, { "id": "R-GGA-5620912", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5620912", "resource": "Reactome", "description": "Anchoring of the basal body to the plasma membrane" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0B4KGJ7-1", "protein_name": "Meckelin", "gene_name": "Dmel\\CG15923", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MRMRMRCFSRAINWCCALFWIALQIPVPICSLTTAATNPSQLPTPHTFRFQNPTQCLKNEFYNLNLFDCVPCNEVAGGDGVQGKLQPDKFTCKCPAGHLSIYERGKTWPTCDEICTPDRSDNCTSVWLPQPRPTNQCSYRYLNSTAAFASQLPVHPLISGIILTHTNPMSRAGDCHSCDMTHNFRYQDFCLASTLLRPYVHYNAFWQATTTPDSSAPSRFGELKFVAFFCLTLRNDTACQQLANLCVLSHFSLEKHSPCSAFLLTQVSDVVMKYAHSGEQVRSLQPFLFYKKGRATKELLSKTLQLPDRKELRLFSTTFGLDGGLKRWGAFHPEMLNMCQQKAPSLRVALPKRESEVSCQLTLERLIDLANQRHNAEFLTVFLNFSSNWQYLLHQLPVLIETLTPENQRPQQEEWQLVKRFQLISASPRDSHLHQTMPRYEDAHKLQQYYSLRYVEDIEIRYTLDKDQPDRVGLPLIRLRYRHIEMGSGNISLSQLYPFTLRISYDQVKRGWDWLILEVALPLLLLLAFAAAVFRLQNLRRRRKADLCQMSSLMEFLLQLAGNVAYALLATTLLLLLLQASNSRLLKILLNTAFVLQFLFLGIHLWRSSQLELFLIDWERPRSSCEGQRLNLDSSSLCSSVRTFVAESSVSAWRVLFTANAWIRLSVTQKYSTLGQVFVVIAGYQFLERFTKGDIFLRCCLIAAAYLLTYLLQIIGHQLFIANPLQKFIDLCSLANISLFSLTEPGFGYYIHGRSPHGFADTDMSSMILQLQRTQTMCGRRGLLMDSDKQAYVILPPRNLHIYLERLLLPFQRSLTGTLSQTMLYQKDIVPSIDGQMERTSIAYASVNRFFCAFIDHAIKDMDYIIKEKSFVEQLLNCEIDNYITENRGTFYIDDSFSFSRVLLLGNHLHIFVLELLLVLSIFLMTSNLLIAAAGACALNILLRQVFRHWVRRNISRKTLIDERFLLXPQNEEQYLREDGFFAI", "length": 984 }, "evidence": [ { "id": "A0A8V0YL98", "url": "https://omabrowser.org/oma/group/A0A8V0YL98/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "A0A287ABM3-1", "protein_name": "Transmembrane protein 67", "gene_name": "TMEM67", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MVTGSCGPGVAMAARSVRSVATVTVFLLLVVPRVSQTQTFFFPFQQPETCGHNQYFDISALSCVPCGANQMQDAGGTSCVCLPGFQMISNNGGPDIICKKCPESMKGVTEDGWNCISCPDGLTAEGKCHCPTGHILVERDVNGTLLSQATCKLCDDSENSFTVANALGTRCVRCEPTFINTSRSCACSEPNILTGELCFSSTGNFPPHMISTARYGELGKSFTSEWFAKYLQSSAAACWVYANLTSCQALGNMCVMNMNSYHFATFDACQLFQFIFENTAGLHTVHSISFWRQNLPWLFFGDQLGLAPQVLSTIPLPTNFSFKGENQNTKLKFVAASYDVRGNFLKWQTLEGGVLQLCPDTETRLNAAYSFGTTYQQNCEIPISKILTDFPTPTFYDVYIEYTDENQHQYIWAVPVLNLNLQHNKIFVNQDSNSGKWLLTRRIFLVDALSGRENDLGSQPRLIRVATQISLSIHLVPNTKNGNIYPPLITIAYSDIDVSDPNSQSVKVSFSVEYEMDQKEAHIQTDIALGVLGGLAVLSSLLKTAGWKRRIGSPMIDLQAQMSVSVLLPTPAQEKRFVTYVGCAFALKALQFLHKLFSQITIDIFFIDWERPKGKILKAVEGEGGVRSATVPVSIWRTYFVANEWNEIQTVRKINPLFQVLTVLFLLEVVGFKNLALMDSSSSLSRSPPSYIAPYSRILRYAVSTVLWLVIGIIQIMFFAVFYERFIEDKIRQFVDLCCMSNISVFLLSHKCFGYYIHGRSVHGHADTNMEEMNMNLKREAENLCSQRGLVPNTDGQTFQIAISSQMRQHYDRIHETLTRRNGPARLLSSSASTFEQSIKAYHTMNKFLGSFIDHVHKEMDYFIKDKLLLERILGMEFMEPMEKSIFYNDEGYSFSSVLYYGNEATLLIYDLLFFCVVDLACQNFILAAFLTYLQQEIFRFIRNTVGQKNLASKTLVDQRFLI", "length": 963 }, "evidence": [ { "id": "A0A8V0YL98", "url": "https://omabrowser.org/oma/group/A0A8V0YL98/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "E9QB24-1", "protein_name": "Meckelin isoform X1", "gene_name": "tmem67", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MATGTRSALLYSVSIIILLKISVFSCQQFSISFRQPSDCGVNSYFDISSLSCVKCGSNQVSSKSGLACECQAGSRVLVSNGVSILCQQCPDADQVVTQDGYECIRCPGTVGKDGKCQCPEGSVLVERDGNGNPLIEARCQACSATDPAFSAPDMKGNRCERCGDSFINSSQSCVCGTSNTLAGGMCFPANSLPTSVASSVIFSQLTLPVQSAWFSSFMYSSAAACLLFSNRTACQSLGNMCVMNMHSSSSINNDVCGLYNTIYRTTAAQGSSQDISYWRTNLPWLYYGDQPGMASQALQNEPLPVGFSFKGAQKNTNIELRAAVYSVRGEFLRWESVGRGNLQLCPDTPTRQQSAFKFGTAYKQSCVLSVSELLTGYPEPLFYDVFLVIQNSQDNRLLAVPLLNANQQFNGQFVNQGSDMSKWFLTRRLMLVDTLSGREKSISSSPVVIRVASDIKIGFQLVPNTQKGQVYPPLMSVAYSDIQIKDPSTQTVTVTFSVEYTMNQEEARIKTDIALGVLGGVAVVHSLLKTASWKRRIASPLIDLETIMKFLVFYAGDLANVFFIITVGTGLYWLIFFKAQLFVSVLLPLPAQEERFVVYVGCAFALKTVQFLHKIFVQLSVDVFFIDWERPRGKTTKHVEGSGETKSQASPVSIWRTYFVANEWNEIQTIRKINPTFQVMAVLFFLEVVGFSNLALRDPSSNLNRSAEEYTPPYSLILRYGVATAMWLCIGLIQMIFFTVFHERFVEDKIRQFVDLCSISNISVLLLSHRCFGYYIHGRSVHGHADTNMDEMNTNLKREAENLCGQRGLLPNSDTQTFQISITNRLRAQYDRIIEPISRRRGPSRLVDATANPCEQSTKAYHTMNRFLGSVIDHAHREMDYIVKDKLLFERVIGMEFIEPLDKSIFYNDDSHSFADVLFYGNEGVLLIFDTLFFCVVDLGKQNFILAAVLTYLQQMIFRLIRNGLGRRNLANKTLVDKRFLI", "length": 982 }, "evidence": [ { "id": "A0A8V0YL98", "url": "https://omabrowser.org/oma/group/A0A8V0YL98/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "P0C152-1", "protein_name": "Meckelin", "gene_name": "Tmem67", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVMRTRPLAAMAVRSCFSALTGTVYLLLVLCEVSWAQIFSFPFQRPETCDLNQYFDISALSCAPCGANQRRDALGTSCICLPGYHMISNNGGPSIICKKCPENMKGVTKDGWDCISCPNGLTAEGKCHCPSGHILVERNVSGSLLSQATCELCDGNENSFTKPNALGTRCVRCEPTFVNTSRSCSCSEPHISTGGLCFSNTGNFPQRLISTERYGELGMSSNSEWFTKYLQATAAACWTHSNLTSCQALGNMCVMNMNSYDSTTFDACRLFHYVFEGAAGLTGVHSVPFWRQNLPWLFYGDQPGLASQVLSTTPLPTNFSFKGQNQLKFVAASYDIRGNFIRWQTVKGGVLQLCPDTERRLDAAYSFGTTYQQNCEISLSKLLADFPSPVFYDIYLEYTDEVQHHYLWAIPVLNLNLQHNKLFVNQDSSSSKWLLTRRIFLVDAVSGRENDLGNQPRVIRVATQISLSIRLVPNTKNGNIYTPLLTIAYSDIDIKNAYSQSVKISFSVKYEMNQGDAFVQTDIALGVLGGLAVLSSLLKTAGWKRRIGSPMIDLQTVMKFLLYYAGDLANVFFIITVGTGLYWLIFFKAQKSVSVLLPMPVQEERFVTYVGCAFAMKALQFLHKLISQITIDIFFIDWERPKGKVLKAVEGEGGVRSATVPVSIWRTYFVANEWNEIQTVRKINPLFQVLTTLFFLEVVGFKNLALMDPSSSLSRSLSDYAAPYSRILRYAVATTIWLVIGIVQVVFFAAFYERFIEDKIRQFVDLCSMSNVSVFLLSHRCFGYYIHGRSVHGHADTNMEDMNMNLRREAENLCSQRGLVPNTDGQTFQIAVSSQMRQHYDRIHETLTRRNGPARLLSSSGSTLEQSIKAYHAMNKFLGSFIDHVHKEMDYFIKDKLLLEKILGMEFMEPLEKSIFYNDESHSFSSVLYYGNEATLLIFDLLFFCVVDLACQNFVLASFLTYLQQEIFRFIRNTVGQKNLATKTLVDERFLI", "length": 992 }, "evidence": [ { "id": "A0A8V0YL98", "url": "https://omabrowser.org/oma/group/A0A8V0YL98/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5HYA8-1", "protein_name": "Meckelin", "gene_name": "TMEM67", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MATRGGAGVAMAVWSLLSARAVTAFLLLFLPRFLQAQTFSFPFQQPEKCDNNQYFDISALSCVPCGANQRQDARGTSCVCLPGFQMISNNGGPAIICKKCPENMKGVTEDGWNCISCPSDLTAEGKCHCPIGHILVERDINGTLLSQATCELCDGNENSFMVVNALGDRCVRCEPTFVNTSRSCACSEPNILTGGLCFSSTGNFPLRRISAARYGEVGMSLTSEWFAKYLQSSAAACWVYANLTSCQALGNMCVMNMNSYDFATFDACGLFQFIFENTAGLSTVHSISFWRQNLPWLFYGDQLGLAPQVLSSTSLPTNFSFKGENQNTKLKFVAASYDIRGNFLKWQTLEGGVLQLCPDTETRLNAAYSFGTTYQQNCEIPISKILIDFPTPIFYDVYLEYTDENQHQYILAVPVLNLNLQHNKIFVNQDSNSGKWLLTRRIFLVDAVSGRENDLGTQPRVIRVATQISLSVHLVPNTINGNIYPPLITIAYSDIDIKDANSQSVKVSFSVTYEMDHGEAHVQTDIALGVLGGLAVLASLLKTAGWKRRIGSPMIDLQTVVKFLVYYAGDLANVFFIITVGTGLYWLIFFKAQKSVSVLLPMPIQEERFVTYVGCAFALKALQFLHKLISQITIDVFFIDWERPKGKVLKAVEGEGGVRSATVPVSIWRTYFVANEWNEIQTVRKINSLFQVLTVLFFLEVVGFKNLALMDSSSSLSRNPPSYIAPYSCILRYAVSAALWLAIGIIQVVFFAVFYERFIEDKIRQFVDLCSMSNISVFLLSHKCFGYYIHGRSVHGHADTNMEEMNMNLKREAENLCSQRGLVPNTDGQTFEIAISNQMRQHYDRIHETLIRKNGPARLLSSSASTFEQSIKAYHMMNKFLGSFIDHVHKEMDYFIKDKLLLERILGMEFMEPMEKSIFYNDEGYSFSSVLYYGNEATLLIFDLLFFCVVDLACQNFILASFLTYLQQEIFRYIRNTVGQKNLASKTLVDQRFLI", "length": 995 }, "evidence": [ { "id": "A0A8V0YL98", "url": "https://omabrowser.org/oma/group/A0A8V0YL98/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "cilium assembly", "id": "GO:0060271", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060271", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YL98", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL98" } ], "pmid": "" }, { "name": "ERAD pathway", "id": "GO:0036503", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036503", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YL98", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL98" } ], "pmid": "" }, { "name": "non-canonical Wnt signaling pathway", "id": "GO:0035567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035567", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YL98", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL98" } ], "pmid": "" }, { "name": "negative regulation of centrosome duplication", "id": "GO:0010826", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010826", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YL98", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL98" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "MKS complex", "id": "GO:0036038", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036038", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YL98", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL98" } ], "pmid": "" }, { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YL98", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL98" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YL98", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL98" } ], "pmid": "" }, { "name": "cytoplasmic vesicle membrane", "id": "GO:0030659", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030659", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YL98", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL98" } ], "pmid": "" }, { "name": "ciliary membrane", "id": "GO:0060170", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060170", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YL98", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL98" } ], "pmid": "" }, { "name": "ciliary transition zone", "id": "GO:0035869", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035869", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YL98", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL98" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "unfolded protein binding", "id": "GO:0051082", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051082", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YL98", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL98" } ], "pmid": "" }, { "name": "filamin binding", "id": "GO:0031005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031005", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YL98", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL98" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 135, "end_pos": 137, "annotation": "n_glycosylation_sequon" }, { "start_pos": 160, "end_pos": 162, "annotation": "n_glycosylation_sequon" }, { "start_pos": 223, "end_pos": 225, "annotation": "n_glycosylation_sequon" }, { "start_pos": 497, "end_pos": 499, "annotation": "n_glycosylation_sequon" }, { "start_pos": 755, "end_pos": 757, "annotation": "n_glycosylation_sequon" }, { "start_pos": 84, "end_pos": 86, "annotation": "n_glycosylation_sequon" }, { "start_pos": 916, "end_pos": 918, "annotation": "n_glycosylation_sequon" }, { "start_pos": 963, "end_pos": 965, 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"A0A8V0YLA2-1", "uniprot_ac": "A0A8V0YLA2", "uniprot_id": "A0A8V0YLA2_CHICK", "mass": { "chemical_mass": 51327.0, "monoisotopic_mass": 51327.0 }, "refseq": {}, "gene_names": [ { "name": "RAB3IP", "type": "recommended", "evidence": [ { "id": "A0A8V0YLA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLA2" } ] } ], "protein_names": [ { "name": "RAB3A interacting protein", "type": "synonym", "evidence": [ { "id": "A0A8V0YLA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLA2/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLA2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLA2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RAB3IP", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLA2", "locus": { "chromosome": "1", "start_pos": 35718335, "end_pos": 35688943, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012133", "url": "https://www.ensembl.org/id/ENSGALG00010012133" } ] } } ], "crossref": [ { "id": "A0A8V0YLA2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YLA2", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd21068", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd21068", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "417850", "url": "https://www.ncbi.nlm.nih.gov/gene/417850", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR009449", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009449", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040351", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040351", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:417850", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417850", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WEIMQLR", "url": "https://omabrowser.org/oma/group/WEIMQLR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YD33", "url": "https://www.orthodb.org/?gene=A0A8V0YD33", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YED2", "url": "https://www.orthodb.org/?gene=A0A8V0YED2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YLA2", "url": "https://www.orthodb.org/?gene=A0A8V0YLA2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14430", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14430", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14430:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14430:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF06428", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06428", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25555", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25555", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-5620912", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5620912", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-5620916", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5620916", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-5620922", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5620922", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-8876198", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8876198", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YD33", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD33", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YD33-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD33-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YED2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YED2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YED2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YED2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLA2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLA2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLA2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLA2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASDPLEGFHEVNLASPTTPDLLGVNEPGTQEQTTSPSVIYRPHPSLVSSAPIQPNALNVSDLPTQPVYSSPRQLNCGEVSGVSINVTDTVLCSTSGPQGGSFNHNNSRKESNNAEKECLQGATVADVAEGNEDIFGLSTDSLSHLRSPSVLEVREKGYERLKEELAKAQRELKLKDEECERLSKVRDQLGQELEELTASLFEEAHKMVKEANVKQAAAEKQLKEAQGKIDVLQAEVAALKTLVLSTSPTSPTKEFQSGGKTPFKKGHARNKSTSSAMGGSHQDLTMMQPIVKDCKEVKADLSLYNEFRSWKDEPTMDRTCPFLDKIYREDIFPCLTFSKSELASAVLEAVENNTLSIEPVGLQPVRFVKASAVECGGPKKCALSGQSKSCKHRIKLGDSSSYYYISPFCRYRITSVCNFFTYIRYIQQGLLKQQDVDQMFWEVMQLRREMSLAKLGYYKEEL", "length": 463, "header": "tr|A0A8V0YLA2-1|A0A8V0YLA2_CHICK Isoform 1 of RAB3A interacting protein OS=Gallus gallus OX=9031 GN=RAB3IP PE=1 SV=1 CANONICAL=A0A8V0YLA2-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YD33-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLA2/entry#A0A8V0YD33-1", "sequence": { "sequence": "MASDPLEGFHEVNLASPTTPDLLGVNEPGTQEQTTSPSVIYRPHPSLVSSAPIQPNALNVSDLPTQPVYSSPRQLNCGEVSGVSINVTDTVLCSTSGPQGGSFNHNNSRKESNNAEKECLQGATVADVAEGNEDIFGLSTDSLSHLRSPSVLEVREKGYERLKEELAKAQRELKLKDEECERLSKVRDQLGQELEELTASLFEEAHKMVKEANVKQAAAEKQLKEAQGKIDVLQAEVAALKTLVLSTSPTSPTKEFQSGGKTPFKKGHARNKSTSSAMGGSHQDLTMMQPIVKDCKEADLSLYNEFRSWKDEPTMDRTCPFLDKIYREDIFPCLTFSKSELASAVLEAVENNTLSIEPVGLQPVRFVKASAVECGGPKKCALSGQSKSCKHRIKLGDSSSYYYISPFCRYRITSVCNFFTYIRYIQQGLLKQQDVDQMFWEVMQLRREMSLAKLGYYKEEL", "length": 461, "header": "tr|A0A8V0YD33-1|A0A8V0YLA2_CHICK Computationally mapped isoform of RAB3A interacting protein OS=Gallus gallus OX=9031 GN=RAB3IP PE=1 SV=1 CANONICAL=A0A8V0YLA2-1" }, "locus": { "chromosome": "1", "start_pos": 35718040, "end_pos": 35695874, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029103.1", "url": "https://www.ensembl.org/id/ENSGALT00010029103.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016862.1", "url": "https://www.ensembl.org/id/ENSGALP00010016862.1" } ] } }, { "isoform_ac": "A0A8V0YED2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLA2/entry#A0A8V0YED2-1", "sequence": { "sequence": "MASDPLEGFHEVNLASPTTPDLLGVNEPGTQEQTTSPSVIYRPHPSLVSSAPIQPNALNVSDLPTQPVYSSPRQLNCGEVSGVSINVTDTVLCSTSGPQGGSFNHNNSRKESNNAEKECLQGATVADVAEGNEDIFGLSTDSLSHLRSPSVLEVREKGYERLKEELAKAQREAHKMVKEANVKQAAAEKQLKEAQGKIDVLQAEVAALKTLVLSTSPTSPTKEFQSGGKTPFKKGHARNKSTSSAMGGSHQDLTMMQPIVKDCKEADLSLYNEFRSWKDEPTMDRTCPFLDKIYREDIFPCLTFSKSELASAVLEAVENNTLSIEPVGLQPVRFVKASAVECGGPKKCALSGQSKSCKHRIKLGDSSSYYYISPFCRYRITSVCNFFTYIRYIQQGLLKQQDVDQMFWEVMQLRREMSLAKLGYYKEEL", "length": 429, "header": "tr|A0A8V0YED2-1|A0A8V0YLA2_CHICK Computationally mapped isoform of RAB3A interacting protein OS=Gallus gallus OX=9031 GN=RAB3IP PE=1 SV=1 CANONICAL=A0A8V0YLA2-1" }, "locus": { "chromosome": "1", "start_pos": 35718040, "end_pos": 35695874, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029106.1", "url": "https://www.ensembl.org/id/ENSGALT00010029106.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016865.1", "url": "https://www.ensembl.org/id/ENSGALP00010016865.1" } ] } }, { "isoform_ac": "A0A8V0YLA2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLA2/entry#A0A8V0YLA2-1", "sequence": { "sequence": "MASDPLEGFHEVNLASPTTPDLLGVNEPGTQEQTTSPSVIYRPHPSLVSSAPIQPNALNVSDLPTQPVYSSPRQLNCGEVSGVSINVTDTVLCSTSGPQGGSFNHNNSRKESNNAEKECLQGATVADVAEGNEDIFGLSTDSLSHLRSPSVLEVREKGYERLKEELAKAQRELKLKDEECERLSKVRDQLGQELEELTASLFEEAHKMVKEANVKQAAAEKQLKEAQGKIDVLQAEVAALKTLVLSTSPTSPTKEFQSGGKTPFKKGHARNKSTSSAMGGSHQDLTMMQPIVKDCKEVKADLSLYNEFRSWKDEPTMDRTCPFLDKIYREDIFPCLTFSKSELASAVLEAVENNTLSIEPVGLQPVRFVKASAVECGGPKKCALSGQSKSCKHRIKLGDSSSYYYISPFCRYRITSVCNFFTYIRYIQQGLLKQQDVDQMFWEVMQLRREMSLAKLGYYKEEL", "length": 463, "header": "tr|A0A8V0YLA2-1|A0A8V0YLA2_CHICK Isoform 1 of RAB3A interacting protein OS=Gallus gallus OX=9031 GN=RAB3IP PE=1 SV=1 CANONICAL=A0A8V0YLA2-1" }, "locus": { "chromosome": "1", "start_pos": 35718040, "end_pos": 35695874, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029105.1", "url": "https://www.ensembl.org/id/ENSGALT00010029105.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016864.1", "url": "https://www.ensembl.org/id/ENSGALP00010016864.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:417850", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417850", "resource": "KEGG Pathway" }, { "id": "R-GGA-5620912", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5620912", "resource": "Reactome", "description": "Anchoring of the basal body to the plasma membrane" }, { "id": "R-GGA-5620916", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5620916", "resource": "Reactome", "description": "VxPx cargo-targeting to cilium" }, { "id": "R-GGA-5620922", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5620922", "resource": "Reactome", "description": "BBSome-mediated cargo-targeting to cilium" }, { "id": "R-GGA-8876198", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8876198", "resource": "Reactome", "description": "RAB GEFs exchange GTP for GDP on RABs" } ], "orthologs": [ { "uniprot_canonical_ac": "G3HZ44-1", "protein_name": "Rab-3A-interacting protein isoform X1", "gene_name": "Rab3ip", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MANDPLEGFHEVNLASPTSPDLLGVCDPGTQEQTTSPSVIYRPHPSSLCSTPLQANALDLSDLPTQPVYSSPRRLNCAEIPNISIHVPDPASAVTSGVAVGLTKLTSRKDIGNAEREFLQGATVTEAPAGSDDIFGLSTDSLSRLRSPSVLEVREKGYERLKEELAKAQRELKLKDEECERLSKVRDQLGQELEELTASLFEEAHKMVREANVKQATAEKQLKEAQGKIDVLQAEVAALKTLVLSSSPTSPTQEPLAAGKTPFKRGHTRNKSTSSAICGSHQDLNVIQPLVKDCKEADLSLYNEFRSWKDEPTMDRTCPFLDKIYQEDIFPCLTFAKSELASAVLEAVENNTLSIEPVGLQPIRFVKASAVECGGPKKCALTGQSKSCKHRIKLGDSSNYYYISPFCRYRITSVCNFFTYIRYIQQGLVKQQDVDQMFWEIMQLRKEMSLAKLGYFKEEL", "length": 460 }, "evidence": [ { "id": "A0A8V0YLA2", "url": "https://omabrowser.org/oma/group/A0A8V0YLA2/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q62739-1", "protein_name": "Rab-3A-interacting protein", "gene_name": "Rab3ip", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MANDPLEGFHEVNLASPTSPDLLGVCDPGTQEQTTSPSVIYRPHPSTLCSATIQANALNLSDLPTQPVYSSPRHLNCAEISNISIHVPEPASSVASEVAAGLTRFTSRKDSCNAEREFLQGATVTEASAGNDDIFGLSTDSLSRLRSPSVLEVREKGYERLKEELAKAQRELKLKDEECERLSKVRDQLGQELEELTASLFEEAHKMVREANVKQATAEKQLKEAQGKIDVLQAEVAALKTLVLSSSPTSPTQEPLAAGKTPFKRGHTRNKSTSSAMSGSHQDFSAIQPIVKDCREADLSLYNEFRSWKDEPTMDRTCPFLDKIYQEDIFPCLTFAKSELASAVLEAVENNTLSIEPVGLQPIRFVKASAVECGGPKKCALTGQSKPCKHRIKLGDSSSYYYISPVCRYRITSVCNFFTYIRYIQQGLVKQQDVDQMFWEVMQLRKEMSLAKLGYFKEEL", "length": 460 }, "evidence": [ { "id": "A0A8V0YLA2", "url": "https://omabrowser.org/oma/group/A0A8V0YLA2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q68EF0-1", "protein_name": "Rab-3A-interacting protein", "gene_name": "Rab3ip", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MANDPLEGFHEVNLASPTSPDLLGVCDPGTQEQTTSPSVIYRPHPSTLCAAPLQANALDLSDLPTQPVYSSPRHFNCAEVSNISAHAPDPASSVPSAVASGLTKLTSRKDSCNAEREFLQGATITEASAGNDDIFGLSTDSLSRLRSPSVLEVREKGYERLKEELAKAQREAHKMVREANVKQATAEKQLKEAQGKIDVLQAEVAALKTLVLSSSPTSPTQEPLAAAKTPFKRGHTRNKSTSSAMGGSHQDLSVIQPIVKDCKEADLSLYNEFRSWKDEPTMDRTCPFLDKIYQEDIFPCLTFAKSELASAVLEAVENNTLSIEPVGLQPIRFVKASAVECGGPKKCALTGQSKPCRHRIRLGDSSCCYYISPFCRYRITSVCNFFTYIRYIQQGLVKQQDVDQMFWEVMQLRKEMSLAKLGYFKEEL", "length": 428 }, "evidence": [ { "id": "A0A8V0YLA2", "url": "https://omabrowser.org/oma/group/A0A8V0YLA2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96QF0-1", "protein_name": "Rab-3A-interacting protein", "gene_name": "RAB3IP", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGLKKMKGLSYDEAFAMANDPLEGFHEVNLASPTSPDLLGVYESGTQEQTTSPSVIYRPHPSALSSVPIQANALDVSELPTQPVYSSPRRLNCAEISSISFHVTDPAPCSTSGVTAGLTKLTTRKDNYNAEREFLQGATITEACDGSDDIFGLSTDSLSRLRSPSVLEVREKGYERLKEELAKAQRELKLKDEECERLSKVRDQLGQELEELTASLFEEAHKMVREANIKQATAEKQLKEAQGKIDVLQAEVAALKTLVLSSSPTSPTQEPLPGGKTPFKKGHTRNKSTSSAMSGSHQDLSVIQPIVKDCKEADLSLYNEFRLWKDEPTMDRTCPFLDKIYQEDIFPCLTFSKSELASAVLEAVENNTLSIEPVGLQPIRFVKASAVECGGPKKCALTGQSKSCKHRIKLGDSSNYYYISPFCRYRITSVCNFFTYIRYIQQGLVKQQDVDQMFWEVMQLRKEMSLAKLGYFKEEL", "length": 476 }, "evidence": [ { "id": "A0A8V0YLA2", "url": "https://omabrowser.org/oma/group/A0A8V0YLA2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLA2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLA2" } ], "pmid": "" }, { "name": "protein targeting to membrane", "id": "GO:0006612", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006612", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLA2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLA2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "guanyl-nucleotide exchange factor activity", "id": "GO:0005085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005085", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLA2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLA2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLA2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLA2" } ], "pmid": "" }, { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLA2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLA2" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLA2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLA2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 106, "end_pos": 108, "annotation": "n_glycosylation_sequon" }, { "start_pos": 271, "end_pos": 273, "annotation": "n_glycosylation_sequon" }, { "start_pos": 353, "end_pos": 355, "annotation": "n_glycosylation_sequon" }, { "start_pos": 59, "end_pos": 61, "annotation": "n_glycosylation_sequon" }, { "start_pos": 86, "end_pos": 88, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YLA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLA2" }, { "id": "PF06428", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06428" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "GDP/GTP exchange factor Sec2 N-terminal", "eco_id": "ECO_0000259", "start_pos": 158, "end_pos": 243, "start_aa": "Gly", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 106, "end_pos": 108 }, { "start_pos": 271, "end_pos": 273 }, { "start_pos": 353, "end_pos": 355 }, { "start_pos": 59, "end_pos": 61 }, { "start_pos": 86, "end_pos": 88 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YIS2-1", "uniprot_ac": "A0A8V0YIS2", "uniprot_id": "A0A8V0YIS2_CHICK", "mass": { "chemical_mass": 47980.0, "monoisotopic_mass": 47980.0 }, "refseq": {}, "gene_names": [ { "name": "GULP1", "type": "recommended", "evidence": [ { "id": "A0A8V0YIS2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIS2" } ] } ], "protein_names": [ { "name": "PTB domain-containing engulfment adapter protein 1", "type": "recommended", "evidence": [ { "id": "A0A8V0YIS2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIS2/entry#names_and_taxonomy" } ] }, { "name": "Cell death protein 6 homolog", "type": "synonym", "evidence": [ { "id": "A0A8V0YIS2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIS2/entry#names_and_taxonomy" } ] }, { "name": "PTB domain adapter protein CED-6", "type": "synonym", "evidence": [ { "id": "A0A8V0YIS2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIS2/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIS2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIS2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "GULP1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIS2", "locus": { "chromosome": "7", "start_pos": 838066, "end_pos": 983640, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013271", "url": "https://www.ensembl.org/id/ENSGALG00010013271" } ] } } ], "crossref": [ { "id": "A0A8V0YIS2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YIS2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000054944", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000054944", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd01273", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01273", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "423988", "url": "https://www.ncbi.nlm.nih.gov/gene/423988", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006020", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006020", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051133", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051133", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q2U954", "url": "https://www.orthodb.org/?gene=A0A3Q2U954", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YD44", "url": "https://www.orthodb.org/?gene=A0A8V0YD44", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YIQ3", "url": "https://www.orthodb.org/?gene=A0A8V0YIQ3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YIS2", "url": "https://www.orthodb.org/?gene=A0A8V0YIS2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YIS6", "url": "https://www.orthodb.org/?gene=A0A8V0YIS6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YJH7", "url": "https://www.orthodb.org/?gene=A0A8V0YJH7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YLE7", "url": "https://www.orthodb.org/?gene=A0A8V0YLE7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YLF2", "url": "https://www.orthodb.org/?gene=A0A8V0YLF2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YRB4", "url": "https://www.orthodb.org/?gene=A0A8V0YRB4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YRD5", "url": "https://www.orthodb.org/?gene=A0A8V0YRD5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11232", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11232", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11232:SF77", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11232:SF77", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00640", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00640", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A3Q2U954", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U954", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2U954-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U954-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YD44", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD44", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YD44-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD44-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YIQ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIQ3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YIQ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIQ3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YIS2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIS2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YIS2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIS2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YIS6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIS6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YIS6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIS6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJH7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJH7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJH7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJH7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLE7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLE7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLE7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLE7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLF2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLF2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLF2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLF2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YRB4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRB4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YRB4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRB4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YRD5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRD5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YRD5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRD5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNRAFSRKKDKTWMHTPEALSKHYIPYNAKFLGSTEVEQPKGTEVVRDAVRKLKFARHIKKSEGQKTPKVELQISIYGVKILDPKTKEVQHNCQLHRISFCADDKTDKRIFTFICKDSESNKHLCYVFDSEKCAEEITLTIGQAFDLAYRKFLESGGKDVETRKQIAGLQKRIQELETENTELKNKVQDLENQLRITQVHAPPLLHIKCDNDEHMFQRPSTFFWCNSEDSPPPCLDISSITLTPRSSPDSRLPSGLLIPPPSKSGLPKPSSEYSCPRPRAGCVTPKSPSTDIFDMVPFSPISPQSSTPTRNGTQPPPVPSRSAEIKRDLFGAEPFDPFSCGAGDFPPDIQSKLDEMQKWGLDSLWDWTLSGIARKGLIRSFKLAKINPSCGKKSYILFWLPLWKEGKEKDGAQSLLTLLEVSVTV", "length": 425, "header": "tr|A0A8V0YIS2-1|A0A8V0YIS2_CHICK Isoform 1 of PTB domain-containing engulfment adapter protein 1 OS=Gallus gallus OX=9031 GN=GULP1 PE=1 SV=1 CANONICAL=A0A8V0YIS2-1" }, "isoforms": [ { "isoform_ac": "A0A3Q2U954-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIS2/entry#A0A3Q2U954-1", "sequence": { "sequence": "MNRAFSRKKDKTWMHTPEALSKHYIPYNAKFLGSTEVEQPKGTEVVRDAVRKLKFARHIKKSEGQKTPKVELQISIYGVKILDPKTKEVQHNCQLHRISFCADDKTDKRIFTFICKDSESNKHLCYVFDSEKCAEEITLTIGQAFDLAYRKFLESGGKDVETRKQIAGLQKRIQELETENTELKNKVQDLENQLRITQVHAPPLLHIKCDNDEHMFQRPSTFFWCNSEDSPPPCLDISSITLTPRSSPDSRLPSGLLIPPPSKSGLPKPSSEYSCPRPRAGCVTPKSPSTDIFDMVPFSPISPQSSTPTRNGTQPPPVPSRSAEIKRDLFGAEPFDPFSCGAGDFPPDIQSKLDEMQEGFKMGLTLEGTVFCLDPLDSRC", "length": 380, "header": "tr|A0A3Q2U954-1|A0A3Q2U954_CHICK Computationally mapped isoform of PTB domain-containing engulfment adapter protein 1 OS=Gallus gallus OX=9031 GN=GULP1 PE=1 SV=1 CANONICAL=A0A8V0YIS2-1" }, "locus": { "chromosome": "7", "start_pos": 925349, "end_pos": 860310, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031914.1", "url": "https://www.ensembl.org/id/ENSGALT00010031914.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018712.1", "url": "https://www.ensembl.org/id/ENSGALP00010018712.1" } ] } }, { "isoform_ac": "A0A8V0YD44-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIS2/entry#A0A8V0YD44-1", "sequence": { "sequence": "MNRAFSRKKDKTWMHTPEALSKHYIPYNAKFARHIKKSEGQKTPKVELQISIYGVKILDPKTKEVQHNCQLHRISFCADDKTDKRIFTFICKDSESNKHLCYVFDSEKCAEEITLTIGQAFDLAYRKFLESGGKDVETRKQIAGLQKRIQELETENTELKNKVQDLENQLRITQVHAPPLLHIKCDNDEHMFQRPSTFFWCNSEDSPPPCLDISSITLTPRSSPDSRLPSGLLIPPPSKSGLPKPSSEYSCPRPRAGCVTPKSPSTDIFDMVPFSPISPQSSTPTRNGTQPPPVPSRSAEIKRDLFGAEPFDPFSCGAGDFPPDIQSKLDEMQEGFKMGLTLEGTVFCLDPLDSRC", "length": 356, "header": "tr|A0A8V0YD44-1|A0A8V0YIS2_CHICK Computationally mapped isoform of PTB domain-containing engulfment adapter protein 1 OS=Gallus gallus OX=9031 GN=GULP1 PE=1 SV=1 CANONICAL=A0A8V0YIS2-1" }, "locus": { "chromosome": "7", "start_pos": 925349, "end_pos": 860310, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031909.1", "url": "https://www.ensembl.org/id/ENSGALT00010031909.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018707.1", "url": "https://www.ensembl.org/id/ENSGALP00010018707.1" } ] } }, { "isoform_ac": "A0A8V0YIQ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIS2/entry#A0A8V0YIQ3-1", "sequence": { "sequence": "DNSPSLSTALARQKVEHPYIKFLGSTEVEQPKGTEVVRDAVRKLKFARHIKKSEGQKTPKVELQISIYGVKILDPKTKEVQHNCQLHRISFCADDKTDKRIFTFICKDSESNKHLCYVFDSEKCAEEITLTIGQAFDLAYRKFLESGGKDVETRKQIAGLQKRIQELETENTELKNKVQDLENQLRITQVHAPPAGCVTPKSPSTDIFDMVPFSPISPQSSTPTRNGTQPPPVPSRSAEIKRDLFGAEPFDPFSCGAGDFPPDIQSKLDEMQEGFKMGLTLEGTVFCLDPLDSRC", "length": 295, "header": "tr|A0A8V0YIQ3-1|A0A8V0YIQ3_CHICK Computationally mapped isoform of PTB domain-containing engulfment adapter protein 1 OS=Gallus gallus OX=9031 GN=GULP1 PE=1 SV=1 CANONICAL=A0A8V0YIS2-1" }, "locus": { "chromosome": "7", "start_pos": 900997, "end_pos": 860310, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031900.1", "url": "https://www.ensembl.org/id/ENSGALT00010031900.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018701.1", "url": "https://www.ensembl.org/id/ENSGALP00010018701.1" } ] } }, { "isoform_ac": "A0A8V0YIS2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIS2/entry#A0A8V0YIS2-1", "sequence": { "sequence": "MNRAFSRKKDKTWMHTPEALSKHYIPYNAKFLGSTEVEQPKGTEVVRDAVRKLKFARHIKKSEGQKTPKVELQISIYGVKILDPKTKEVQHNCQLHRISFCADDKTDKRIFTFICKDSESNKHLCYVFDSEKCAEEITLTIGQAFDLAYRKFLESGGKDVETRKQIAGLQKRIQELETENTELKNKVQDLENQLRITQVHAPPLLHIKCDNDEHMFQRPSTFFWCNSEDSPPPCLDISSITLTPRSSPDSRLPSGLLIPPPSKSGLPKPSSEYSCPRPRAGCVTPKSPSTDIFDMVPFSPISPQSSTPTRNGTQPPPVPSRSAEIKRDLFGAEPFDPFSCGAGDFPPDIQSKLDEMQKWGLDSLWDWTLSGIARKGLIRSFKLAKINPSCGKKSYILFWLPLWKEGKEKDGAQSLLTLLEVSVTV", "length": 425, "header": "tr|A0A8V0YIS2-1|A0A8V0YIS2_CHICK Isoform 1 of PTB domain-containing engulfment adapter protein 1 OS=Gallus gallus OX=9031 GN=GULP1 PE=1 SV=1 CANONICAL=A0A8V0YIS2-1" }, "locus": { "chromosome": "7", "start_pos": 925349, "end_pos": 856659, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031925.1", "url": "https://www.ensembl.org/id/ENSGALT00010031925.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018722.1", "url": "https://www.ensembl.org/id/ENSGALP00010018722.1" } ] } }, { "isoform_ac": "A0A8V0YIS6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIS2/entry#A0A8V0YIS6-1", "sequence": { "sequence": "MNRAFSRKKDKTWMHTPEALSKHYIPYNAKFLGSTEVEQPKGTEVVRDAVRKLKFARHIKKSEGQKTPKVELQISIYGVKILDPKTKEVQHNCQLHRISFCADDKTDKRIFTFICKDSESNKHLCYVFDSEKCAEEITLTIGQAFDLAYRKFLESGGKDVETRKQIAGLQKRIQELETENTELKNKVQDLENQLRITQVHAPPAGCVTPKSPSTDIFDMVPFSPISPQSSTPTRNGTQPPPVPSRSAEIKRDLFGAEPFDPFSCGAGDFPPDIQSKLDEMQKWGLDSLWDWTLSGIARKGLIRSFKLAKINPSCGKKSYILFWLPLWKEGKEKDGAQSLLTLLEVSKKMTMDQSIFHPSLYD", "length": 362, "header": "tr|A0A8V0YIS6-1|A0A8V0YIS6_CHICK Computationally mapped isoform of PTB domain-containing engulfment adapter protein 1 OS=Gallus gallus OX=9031 GN=GULP1 PE=1 SV=1 CANONICAL=A0A8V0YIS2-1" }, "locus": { "chromosome": "7", "start_pos": 925349, "end_pos": 838179, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031930.1", "url": "https://www.ensembl.org/id/ENSGALT00010031930.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018727.1", "url": "https://www.ensembl.org/id/ENSGALP00010018727.1" } ] } }, { "isoform_ac": "A0A8V0YJH7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIS2/entry#A0A8V0YJH7-1", "sequence": { "sequence": "MNRAFSRKKDKTWMHTPEALSKHYIPYNAKFLGSTEVEQPKGTEVVRDAVRKLKFARHIKKSEGQKTPKVELQISIYGVKILDPKTKEVQHNCQLHRISFCADDKTDKRIFTFICKDSESNKHLCYVFDSEKCAEEITLTIGQAFDLAYRKFLESGGKDVETRKQIAGLQKRIQELETENTELKNKVQDLENQLRITQVHAPPLLHIKCDNDEHMFQRPSTFFWCNSEDSPPPCLDISSITLTPRSSPDSRLPSGLLIPPPSKSGLPKPSSEYSCPRPRAGCVTPKSPSTDIFDMVPFSPISPQSSTPTRNGTQPPPVPSRSAEIKRDLFGAEPFDPFSCGAGDFPPDIQSKLDEMQRQRWRGSKWD", "length": 367, "header": "tr|A0A8V0YJH7-1|A0A8V0YJH7_CHICK Computationally mapped isoform of PTB domain-containing engulfment adapter protein 1 OS=Gallus gallus OX=9031 GN=GULP1 PE=1 SV=1 CANONICAL=A0A8V0YIS2-1" }, "locus": { "chromosome": "7", "start_pos": 925349, "end_pos": 860360, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031916.1", "url": "https://www.ensembl.org/id/ENSGALT00010031916.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018714.1", "url": "https://www.ensembl.org/id/ENSGALP00010018714.1" } ] } }, { "isoform_ac": "A0A8V0YLE7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIS2/entry#A0A8V0YLE7-1", "sequence": { "sequence": "MNRAFSRKKDKTWMHTPEALSKHYIPYNAKFLGSTEVEQPKGTEVVRDAVRKLKFARHIKKSEGQKTPKVELQISIYGVKILDPKTKEVQHNCQLHRISFCADDKTDKRIFTFICKDSESNKHLCYVFDSEKCAEEITLTIGQAFDLAYRKFLESGGKDVETRKQIAGLQKRIQELETENTELKNKVQDLENQLRITQVHAPPLLHIKCDNDEHMFQRPSTFFWCNSEDSPPPCLDISSITLTPRSSPDSRLPSGLLIPPPSKSGLPKPSSEYSCPRPRVILLCKSFLFFDFPVFFLSCVINMLKCHILYSDERTDQIYL", "length": 320, "header": "tr|A0A8V0YLE7-1|A0A8V0YLE7_CHICK Computationally mapped isoform of PTB domain-containing engulfment adapter protein 1 OS=Gallus gallus OX=9031 GN=GULP1 PE=1 SV=1 CANONICAL=A0A8V0YIS2-1" }, "locus": { "chromosome": "7", "start_pos": 925349, "end_pos": 873797, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031906.1", "url": "https://www.ensembl.org/id/ENSGALT00010031906.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018705.1", "url": "https://www.ensembl.org/id/ENSGALP00010018705.1" } ] } }, { "isoform_ac": "A0A8V0YLF2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIS2/entry#A0A8V0YLF2-1", "sequence": { "sequence": "TVLLVGRKFLGSTEVEQPKGTEVVRDAVRKLKFARHIKKSEGQKTPKVELQISIYGVKILDPKTKEVQHNCQLHRISFCADDKTDKRIFTFICKDSESNKHLCYVFDSEKCAEEITLTIGQAFDLAYRKFLESGGKDVETRKQIAGLQKRIQELETENTELKNKVQDLENQLRITQVHAPPLLHIKCDNDEHMFQRPSTFFWCNSEDSPPPCLDISSITLTPRSSPDSRLPSGLLIPPPSKSGLPKPSSEYSCPRPRAGCVTPKSPSTDIFDMVPFSPISPQSSTPTRNGTQPPPVPSRSAEIKRDLFGAEPFDPFSCGAGDFPPDIQSKLDEMQEGFKMGLTLEGTVFCLDPLDSRC", "length": 358, "header": "tr|A0A8V0YLF2-1|A0A8V0YLF2_CHICK Computationally mapped isoform of PTB domain-containing engulfment adapter protein 1 OS=Gallus gallus OX=9031 GN=GULP1 PE=1 SV=1 CANONICAL=A0A8V0YIS2-1" }, "locus": { "chromosome": "7", "start_pos": 925345, "end_pos": 860310, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031912.1", "url": "https://www.ensembl.org/id/ENSGALT00010031912.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018710.1", "url": "https://www.ensembl.org/id/ENSGALP00010018710.1" } ] } }, { "isoform_ac": "A0A8V0YRB4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIS2/entry#A0A8V0YRB4-1", "sequence": { "sequence": "MKSNSRGVLFFRGQVSFVLLHSFLNTNYLGGKITISVLYEFLGSTEVEQPKGTEVVRDAVRKLKFARHIKKSEGQKTPKVELQISIYGVKILDPKTKEVQHNCQLHRISFCADDKTDKRIFTFICKDSESNKHLCYVFDSEKCAEEITLTIGQAFDLAYRKFLESGGKDVETRKQIAGLQKRIQELETENTELKNKVQDLENQLRITQVHAPPAGCVTPKSPSTDIFDMVPFSPISPQSSTPTRNGTQPPPVPSRSAEIKRDLFGAEPFDPFSCGAGDFPPDIQSKLDEMQEGFKMGLTLEGTVFCLDPLDSRC", "length": 314, "header": "tr|A0A8V0YRB4-1|A0A8V0YRB4_CHICK Computationally mapped isoform of PTB domain-containing engulfment adapter protein 1 OS=Gallus gallus OX=9031 GN=GULP1 PE=1 SV=1 CANONICAL=A0A8V0YIS2-1" }, "locus": { "chromosome": "7", "start_pos": 911261, "end_pos": 860310, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031903.1", "url": "https://www.ensembl.org/id/ENSGALT00010031903.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018703.1", "url": "https://www.ensembl.org/id/ENSGALP00010018703.1" } ] } }, { "isoform_ac": "A0A8V0YRD5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIS2/entry#A0A8V0YRD5-1", "sequence": { "sequence": "MNRAFSRKKDKTWMHTPEALSKHYIPYNAKFLGSTEVEQPKGTEVVRDAVRKLKFARHIKKSEGQKTPKVELQISIYGVKILDPKTKEVQHNCQLHRISFCADDKTDKRIFTFICKDSESNKHLCYVFDSEKCAEEITLTIGQAFDLAYRKFLESGGKDVETRKQIAGLQKRIQELETENTELKNKVQDLENQLRITQVHAPPAGCVTPKSPSTDIFDMVPFSPISPQSSTPTRNGTQPPPVPSRSAEIKRDLFGAEPFDPFSCGAGDFPPDIQSKLDEMQKWGLDSLWDWTLSGIARKGLIRSFKLAKINPSCGKKSYILFWLPLWKEGKEKDGAQSLLTLLELLWLSQDYTRAASQQI", "length": 360, "header": "tr|A0A8V0YRD5-1|A0A8V0YRD5_CHICK Computationally mapped isoform of PTB domain-containing engulfment adapter protein 1 OS=Gallus gallus OX=9031 GN=GULP1 PE=1 SV=1 CANONICAL=A0A8V0YIS2-1" }, "locus": { "chromosome": "7", "start_pos": 925349, "end_pos": 855419, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031927.1", "url": "https://www.ensembl.org/id/ENSGALT00010031927.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018724.1", "url": "https://www.ensembl.org/id/ENSGALP00010018724.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIS2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIS2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "phagocytosis", "id": "GO:0006909", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006909", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIS2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIS2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 311, "end_pos": 313, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YIS2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIS2" }, { "id": "PS01179", "database": "PROSITE", "url": "https://prosite.expasy.org/PS01179" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PID", "eco_id": "ECO_0000259", "start_pos": 27, "end_pos": 155, "start_aa": "Tyr", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 311, "end_pos": 313 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": 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"publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YLJ3-1", "uniprot_ac": "A0A8V0YLJ3", "uniprot_id": "A0A8V0YLJ3_CHICK", "mass": { "chemical_mass": 37526.0, "monoisotopic_mass": 37526.0 }, "refseq": {}, "gene_names": [ { "name": "AKR1D1", "type": "recommended", "evidence": [ { "id": "A0A8V0YLJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLJ3" } ] } ], "protein_names": [ { "name": "Aldo-keto reductase family 1 member D1", "type": "synonym", "evidence": [ { "id": "A0A8V0YLJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLJ3/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLJ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLJ3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "AKR1D1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLJ3", "locus": { "chromosome": "1", "start_pos": 56629958, "end_pos": 56593491, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013290", "url": "https://www.ensembl.org/id/ENSGALG00010013290" } ] } } ], "crossref": [ { "id": "A0A8V0YLJ3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YLJ3", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd19109", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd19109", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR018170", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018170", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020471", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020471", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023210", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023210", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036812", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036812", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044483", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044483", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YD87", "url": "https://www.orthodb.org/?gene=A0A8V0YD87", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YLJ3", "url": "https://www.orthodb.org/?gene=A0A8V0YLJ3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YLJ7", "url": "https://www.orthodb.org/?gene=A0A8V0YLJ7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YLK1", "url": "https://www.orthodb.org/?gene=A0A8V0YLK1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YRF9", "url": "https://www.orthodb.org/?gene=A0A8V0YRF9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YRG8", "url": "https://www.orthodb.org/?gene=A0A8V0YRG8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YRH3", "url": "https://www.orthodb.org/?gene=A0A8V0YRH3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11732", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11732", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00248", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00248", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-193368", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-193368", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-193775", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-193775", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-193807", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-193807", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YD87", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD87", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YD87-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD87-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLJ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLJ3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLJ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLJ3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLJ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLJ7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLJ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLJ7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLK1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLK1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLK1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLK1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YRF9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRF9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YRF9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRF9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YRG8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRG8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YRG8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRG8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YRH3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRH3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YRH3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRH3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSLTAESHRVPLSDGNSIPLLGLGTYADPQKTPKGTCLESVKIAIDTGYRHIDGAFVYYNEHEVGQAIREKIAEGKIKREDIFYCGKLWNTCHPPELVRPTLEKTLKILQLDYVDLYIIELPMAFKPGEAIYPRDENGKIIYHETNLCATWEAMEACKDAGLAKSIGVSNFNRRQLEMILNKPGLKHKPVSNQVECHPYFTQPKLLEFCRQHDIVIVGYSPLGTSRDETWVNVSSPPLLEDPVLNAIGKKYNKTAAQVALRFSIQRGVVVIPKSFNPQRIRENFQIFDFSLTEKEMKEIEALNKNVRYVELLILCYGHSSLPVIPSHLISSG", "length": 332, "header": "tr|A0A8V0YLJ3-1|A0A8V0YLJ3_CHICK Isoform 1 of Aldo-keto reductase family 1 member D1 OS=Gallus gallus OX=9031 GN=AKR1D1 PE=1 SV=1 CANONICAL=A0A8V0YLJ3-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YD87-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLJ3/entry#A0A8V0YD87-1", "sequence": { "sequence": "MSLTAESHRVPLSDGNSIPLLGLGTYADPQKTPKGTCLESVKIAIDTGYRHIDGAFVYYNEHEVGQAIREKIAEGKIKREDIFYCGKLWNTCHPPELVRPTLEKTLKILQLDYVDLYIIELPMAFKPGEAIYPRDENGKIIYHETNLCATWEAMEACKDAGLAKSIGVSNFNRRQLEMILNKPGLKHKPVSNQVECHPYFTQPKLLEFCRQHDIVIVGYSPLGTSRDETWVNVSSPPLLEDPVLNAIGKKYNKTAAQVALRFSIQRGVVVIPKSFNPQRIRENFQIFDFSLTEKEMKEIEALNKNVRYVELLMSLMKMLNKMGPSTEPWETLLATVSAMDILPYQLFQATLSPLGEAFWYTRGL", "length": 364, "header": "tr|A0A8V0YD87-1|A0A8V0YLJ3_CHICK Computationally mapped isoform of Aldo-keto reductase family 1 member D1 OS=Gallus gallus OX=9031 GN=AKR1D1 PE=1 SV=1 CANONICAL=A0A8V0YLJ3-1" }, "locus": { "chromosome": "1", "start_pos": 56628573, "end_pos": 56595950, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031957.1", "url": "https://www.ensembl.org/id/ENSGALT00010031957.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018749.1", "url": "https://www.ensembl.org/id/ENSGALP00010018749.1" } ] } }, { "isoform_ac": "A0A8V0YLJ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLJ3/entry#A0A8V0YLJ3-1", "sequence": { "sequence": "MSLTAESHRVPLSDGNSIPLLGLGTYADPQKTPKGTCLESVKIAIDTGYRHIDGAFVYYNEHEVGQAIREKIAEGKIKREDIFYCGKLWNTCHPPELVRPTLEKTLKILQLDYVDLYIIELPMAFKPGEAIYPRDENGKIIYHETNLCATWEAMEACKDAGLAKSIGVSNFNRRQLEMILNKPGLKHKPVSNQVECHPYFTQPKLLEFCRQHDIVIVGYSPLGTSRDETWVNVSSPPLLEDPVLNAIGKKYNKTAAQVALRFSIQRGVVVIPKSFNPQRIRENFQIFDFSLTEKEMKEIEALNKNVRYVELLILCYGHSSLPVIPSHLISSG", "length": 332, "header": "tr|A0A8V0YLJ3-1|A0A8V0YLJ3_CHICK Isoform 1 of Aldo-keto reductase family 1 member D1 OS=Gallus gallus OX=9031 GN=AKR1D1 PE=1 SV=1 CANONICAL=A0A8V0YLJ3-1" }, "locus": { "chromosome": "1", "start_pos": 56628545, "end_pos": 56595950, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031961.1", "url": "https://www.ensembl.org/id/ENSGALT00010031961.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018752.1", "url": "https://www.ensembl.org/id/ENSGALP00010018752.1" } ] } }, { "isoform_ac": "A0A8V0YLJ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLJ3/entry#A0A8V0YLJ7-1", "sequence": { "sequence": "MSLTAESHRVPLSDGNSIPLLGLGTYADPQKTPKGTCLESVKIAIDTGYRHIDGAFVYYNEHEVGQAIREKIAEGKIKREDIFYCGKLWNTCHPPELVRPTLEKTLKILQLDYVDLYIIELPMAFKAMEACKDAGLAKSIGVSNFNRRQLEMILNKPGLKHKPVSNQVECHPYFTQPKLLEFCRQHDIVIVGYSPLGTSRDETWVNVSSPPLLEDPVLNAIGKKYNKTAAQVALRFSIQRGVVVIPKSFNPQRIRENFQIFDFSLTEKEMKEIEALNKNVRYVELLMWRDHPEYPFNDEY", "length": 300, "header": "tr|A0A8V0YLJ7-1|A0A8V0YLJ7_CHICK Computationally mapped isoform of Aldo-keto reductase family 1 member D1 OS=Gallus gallus OX=9031 GN=AKR1D1 PE=1 SV=1 CANONICAL=A0A8V0YLJ3-1" }, "locus": { "chromosome": "1", "start_pos": 56629693, "end_pos": 56595950, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031966.1", "url": "https://www.ensembl.org/id/ENSGALT00010031966.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018757.1", "url": "https://www.ensembl.org/id/ENSGALP00010018757.1" } ] } }, { "isoform_ac": "A0A8V0YLK1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLJ3/entry#A0A8V0YLK1-1", "sequence": { "sequence": "MPKFTRTERMLFLTSSPVQNIGLLTTGGQPTNLRENMKPEAPSFPVNNSFSPSFLLTSENWGDYTGRGWPLYLNRLLTSFVQTPKGTCLESVKIAIDTGYRHIDGAFVYYNEHEVGQAIREKIAEGKIKREDIFYCGKLWNTCHPPELVRPTLEKTLKILQLDYVDLYIIELPMAFKPGEAIYPRDENGKIIYHETNLCATWEAMEACKDAGLAKSIGVSNFNRRQLEMILNKPGLKHKPVSNQVECHPYFTQPKLLEFCRQHDIVIVGYSPLGTSRDETWVNVSSPPLLEDPVLNAIGKKYNKTAAQVALRFSIQRGVVVIPKSFNPQRIRENFQIFDFSLTEKEMKEIEALNKNVRYVELLMWRDHPEYPFNDEY", "length": 377, "header": "tr|A0A8V0YLK1-1|A0A8V0YLK1_CHICK Computationally mapped isoform of Aldo-keto reductase family 1 member D1 OS=Gallus gallus OX=9031 GN=AKR1D1 PE=1 SV=1 CANONICAL=A0A8V0YLJ3-1" }, "locus": { "chromosome": "1", "start_pos": 56629693, "end_pos": 56593690, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031971.1", "url": "https://www.ensembl.org/id/ENSGALT00010031971.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018762.1", "url": "https://www.ensembl.org/id/ENSGALP00010018762.1" } ] } }, { "isoform_ac": "A0A8V0YRF9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLJ3/entry#A0A8V0YRF9-1", "sequence": { "sequence": "MSLTAESHRVPLSDGNSIPLLGLGTYADPQKTPKGTCLESVKIAIDTGYRHIDGAFVYYNEHEVGQAIREKIAEGKIKREDIFYCGKLWNTCHPPELVRPTLEKTLKILQLDYVDLYIIELPMAFKPGEAIYPRDENGKIIYHETNLCATWEAMEACKDAGLAKSIGVSNFNRRQLEMILNKPGLKHKPVSNQVECHPYFTQPKLLEFCRQHDIVIVGYSPLGTSRDETWVNVSSPPLLEDPVLNAIGKKYNKTAAQVALRFSIQRGVVVIPKSFNPQRIRENFQIFDFSLTEKEMKEIEALNKNVRYVELLM", "length": 313, "header": "tr|A0A8V0YRF9-1|A0A8V0YRF9_CHICK Computationally mapped isoform of Aldo-keto reductase family 1 member D1 OS=Gallus gallus OX=9031 GN=AKR1D1 PE=1 SV=1 CANONICAL=A0A8V0YLJ3-1" }, "locus": { "chromosome": "1", "start_pos": 56625982, "end_pos": 56595950, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031953.1", "url": "https://www.ensembl.org/id/ENSGALT00010031953.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018745.1", "url": "https://www.ensembl.org/id/ENSGALP00010018745.1" } ] } }, { "isoform_ac": "A0A8V0YRG8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLJ3/entry#A0A8V0YRG8-1", "sequence": { "sequence": "MSLTAESHRVPLSDGNSIPLLGLGTYADPQKPGEAIYPRDENGKIIYHETNLCATWEAMEACKDAGLAKSIGVSNFNRRQLEMILNKPGLKHKPVSNQVECHPYFTQPKLLEFCRQHDIVIVGYSPLGTSRDETWVNVSSPPLLEDPVLNAIGKKYNKTAAQVALRFSIQRGVVVIPKSFNPQRIRENFQIFDFSLTEKEMKEIEALNKNVRYVELLMWRDHPEYPFNDEY", "length": 231, "header": "tr|A0A8V0YRG8-1|A0A8V0YRG8_CHICK Computationally mapped isoform of Aldo-keto reductase family 1 member D1 OS=Gallus gallus OX=9031 GN=AKR1D1 PE=1 SV=1 CANONICAL=A0A8V0YLJ3-1" }, "locus": { "chromosome": "1", "start_pos": 56629693, "end_pos": 56595950, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031964.1", "url": "https://www.ensembl.org/id/ENSGALT00010031964.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018755.1", "url": "https://www.ensembl.org/id/ENSGALP00010018755.1" } ] } }, { "isoform_ac": "A0A8V0YRH3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLJ3/entry#A0A8V0YRH3-1", "sequence": { "sequence": "MLLGCFILCWEHSRSRTVAKSCGWHRRVLKSLCSGMTPKGTCLESVKIAIDTGYRHIDGAFVYYNEHEVGQAIREKIAEGKIKREDIFYCGKLWNTCHPPELVRPTLEKTLKILQLDYVDLYIIELPMAFKPGEAIYPRDENGKIIYHETNLCATWEAMEACKDAGLAKSIGVSNFNRRQLEMILNKPGLKHKPVSNQVECHPYFTQPKLLEFCRQHDIVIVGYSPLGTSRDETWVNVSSPPLLEDPVLNAIGKKYNKTAAQVALRFSIQRGVVVIPKSFNPQRIRENFQIFDFSLTEKEMKEIEALNKNVRYVELLMWRDHPEYPFNDEY", "length": 331, "header": "tr|A0A8V0YRH3-1|A0A8V0YRH3_CHICK Computationally mapped isoform of Aldo-keto reductase family 1 member D1 OS=Gallus gallus OX=9031 GN=AKR1D1 PE=1 SV=1 CANONICAL=A0A8V0YLJ3-1" }, "locus": { "chromosome": "1", "start_pos": 56629693, "end_pos": 56595053, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031969.1", "url": "https://www.ensembl.org/id/ENSGALT00010031969.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018760.1", "url": "https://www.ensembl.org/id/ENSGALP00010018760.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-193368", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-193368", "resource": "Reactome", "description": "Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol" }, { "id": "R-GGA-193775", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-193775", "resource": "Reactome", "description": "Synthesis of bile acids and bile salts via 24-hydroxycholesterol" }, { "id": "R-GGA-193807", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-193807", "resource": "Reactome", "description": "Synthesis of bile acids and bile salts via 27-hydroxycholesterol" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "bile acid biosynthetic process", "id": "GO:0006699", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006699", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLJ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLJ3" } ], "pmid": "" }, { "name": "digestion", "id": "GO:0007586", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007586", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLJ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLJ3" } ], "pmid": "" }, { "name": "cholesterol catabolic process", "id": "GO:0006707", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006707", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLJ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLJ3" } ], "pmid": "" }, { "name": "C21-steroid hormone metabolic process", "id": "GO:0008207", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008207", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLJ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLJ3" } ], "pmid": "" }, { "name": "androgen metabolic process", "id": "GO:0008209", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008209", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLJ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLJ3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "Delta4-3-oxosteroid 5beta-reductase activity", "id": "GO:0047787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0047787", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLJ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLJ3" } ], "pmid": "" }, { "name": "steroid dehydrogenase activity", "id": "GO:0016229", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016229", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLJ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLJ3" } ], "pmid": "" }, { "name": "aldose reductase (NADPH) activity", "id": "GO:0004032", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004032", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLJ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLJ3" } ], "pmid": "" }, { "name": "ketosteroid monooxygenase activity", "id": "GO:0047086", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0047086", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLJ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLJ3" } ], "pmid": "" }, { "name": "oxidoreductase activity", "id": "GO:0016491", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016491", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLJ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLJ3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLJ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLJ3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 232, "end_pos": 234, "annotation": "n_glycosylation_sequon" }, { "start_pos": 252, "end_pos": 254, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YLJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLJ3" }, { "id": "PF00248", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00248" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "NADP-dependent oxidoreductase", "eco_id": "ECO_0000259", "start_pos": 21, "end_pos": 303, "start_aa": "Leu", "end_aa": "Asn", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 232, "end_pos": 234 }, { "start_pos": 252, "end_pos": 254 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YJW8-1", "uniprot_ac": "A0A8V0YJW8", "uniprot_id": "A0A8V0YJW8_CHICK", "mass": { "chemical_mass": 111533.0, "monoisotopic_mass": 111533.0 }, "refseq": { "ac": "XP_004949454", "name": "SMC5-SMC6 complex localization factor protein 1 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004949454" }, "gene_names": [ { "name": "SLF1", "type": "recommended", "evidence": [ { "id": "A0A8V0YJW8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJW8" } ] }, { "name": "SLF1", "type": "synonym", "evidence": [ { "id": "XP_004949454", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004949454" } ] } ], "protein_names": [ { "name": "SMC5-SMC6 complex localization factor 1", "type": "synonym", "evidence": [ { "id": "A0A8V0YJW8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJW8/entry#names_and_taxonomy" } ] }, { "name": "SMC5-SMC6 complex localization factor protein 1 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_004949454", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004949454" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052572.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_004949454.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004949454", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004949454" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJW8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJW8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SLF1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJW8", "locus": { "chromosome": "Z", "start_pos": 58626195, "end_pos": 58665357, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013327", "url": "https://www.ensembl.org/id/ENSGALG00010013327" } ] } } ], "crossref": [ { "id": "A0A8V0YJW8", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YJW8", "database": "AlphaFoldDB", "categories": [] }, { "id": "427111", "url": "https://www.ncbi.nlm.nih.gov/gene/427111", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001357", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001357", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036420", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036420", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036770", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036770", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042479", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042479", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057595", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057595", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YDJ8", "url": "https://www.orthodb.org/?gene=A0A8V0YDJ8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YJW8", "url": "https://www.orthodb.org/?gene=A0A8V0YJW8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YRQ1", "url": "https://www.orthodb.org/?gene=A0A8V0YRQ1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46677", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46677", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46677:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46677:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF12796", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12796", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16770", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16770", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23294", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23294", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_004949454", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004949454", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YDJ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDJ8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YDJ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDJ8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJW8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJW8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJW8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJW8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YRQ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRQ1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YRQ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRQ1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAPVGPAAGVRSGVRRAGPPVRRRKRRRESLRDRTAAGLWRPALITGPAALPGGSCDSAAAPGVSAASGGRKRRIQFTGFRKREKKALREMLLKLDCVFVDNKKYRNCTHLIAKKLCKSEKFLAACAAGKWILTKEYIINSAESGRWLDETTYEWGYKIEKDTHYSPQMQSAPKRWRKELKNSGAPGAFHRWKVILAVKEGYEQVAAIRRVLEAGKATVCSSQNVESDITHVFILNKFFPVQKEKCFSEAQYYPFQYVGDYLLEKDIQNTEVTQINGFLPAHETDKNKSNMQLIEMKNAVIKHMYFVEAAKQKFAHKDFLNRCNPKVKNTNLSGGRLYIFEELIEEHLLSEVVIELAVGQKYSLPPVQLLHSLLERVLLENIDAVFCAKLHHVLDLILQHDPPWKSTSMLGYYLDLLQCPICKKGTWNLIEMLVRSCLHCKNICHAVPVSGKADEQRTVHKTLLKFFFDLVKAEVESLKKSLVEGTNSQHQQVMPQTVLLKTFWLGSETSVLFTKHINILVDWVIHSYRELESKNDAFRREIACLLNAILGTVVDYWIVSGLLMDRNVFHQIADDLAHYIAIACDDFPISDFKMFICSIPSLWLQMFVAEAVFKKMCLQRNVTISTEPLSLQKIVGPYFLALREVGMCETRKVHKAKEIGHWPGPASQRALQMLNGDEQNQVKVLPDLPSLFRGSKCCTRKRAKASDTKENCSHWVEEMNFYRRNAKGQTALHGACIRNKVERLIQLLSSPGIDINSKDYAGWTPLHEACNHGSTVCVSEILQRCPEVDLLSQVDGVTPLHDALSNGHVEIGKLLLQHGGPVLLQRRDSNGKLPLDYVQSPQVKQELLNIVLPEEKIESFYQRTQQDFSSQQKELWLILFNKMLLNFCSVYNLFSPFTLTLREVAHSNMFLAMTADSHKMKGTFPAHWLVDTYFKELETFQKLPQFIEEVSTYMRAFPGEQMKALLATLETVVKSNQLFA", "length": 980, "header": "tr|A0A8V0YJW8-1|A0A8V0YJW8_CHICK Isoform 1 of SMC5-SMC6 complex localization factor 1 OS=Gallus gallus OX=9031 GN=SLF1 PE=4 SV=1 CANONICAL=A0A8V0YJW8-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YDJ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJW8/entry#A0A8V0YDJ8-1", "sequence": { "sequence": "MAPVGPAAGVRSGVRRAGPPVRRRKRRRESLRDRTAAGLWRPALITGPAALPGGSCDSAAAPGVSAASGGRKRRIQFTGFRKREKKALREMLLKLDCVFVDNKKYRNCTHLIAKKLCKSEKFLAACAAGKWILTKEYIINSAESGRWLDETTYEWGYKIEKDTHYSPQMQSAPKRWRKELKNSGAPGAFHRWKVILAVKEGYEQVAAIRRVLEAGKATVCSSQNVESDITHVFILNKFFPVQKEKCFSEAQYYPFQYVGDYLLEKDIQNTEVTQINGFLPAHETDKNKSNMQLIEMKNAVIKHMYFVEAAKQKFAHKDFLNRCNPKVKNTNLSGGRLYIFEELIEEHLLSEVVIELAVGQKYSLPPVQLLHSLLERVLLENIDAVFCAKLHHVLDLILQHDPPWKSTSMLGYYLDLLQCPICKKGTWNLIEMLVRSCLHCKNICHAVPVSGKADEQRTVHKTLLKFFFDLVKAEVESLKKSLVEGTNSQHQQVMPQTVLLKTFWLGSETSVLFTKHINILVDWVIHSYRELESKNDAFRREIACLLNAILGTVVDYWIVSGLLMDRNVFHQIADDLAHYIAIACDDFPISDFKMFICSIPSLWLQMFVAEAVFKKMCLQRNVTISTEPLSLQKIVGPYFLALREVGMCETRKVHKAKEIGHWPGPASQRALQMLNGDEQNQVKVLPDLPSLFRGSKCCTRKRAKASDTKENCSHWVEEMNFYRRNAKGQTALHGACIRNKVERLIQLLSSPGIDINSKGPVLLQRRDSNGKLPLDYVQSPQVKQELLNIVLPEEKIESFYQRTQQDFSSQQKELWLILFNKMLLNFCSVYNLFSPFTLTLREVAHSNMFLAMTADSHKMKGTFPAHWLVDTYFKELETFQKLPQFIEEVSTYMRAFPGEQMKALLATLETVVKSNQLFA", "length": 919, "header": "tr|A0A8V0YDJ8-1|A0A8V0YJW8_CHICK Computationally mapped isoform of SMC5-SMC6 complex localization factor 1 OS=Gallus gallus OX=9031 GN=SLF1 PE=4 SV=1 CANONICAL=A0A8V0YJW8-1" }, "locus": { "chromosome": "Z", "start_pos": 58665290, "end_pos": 58627199, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032082.1", "url": "https://www.ensembl.org/id/ENSGALT00010032082.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018872.1", "url": "https://www.ensembl.org/id/ENSGALP00010018872.1" } ] } }, { "isoform_ac": "A0A8V0YJW8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJW8/entry#A0A8V0YJW8-1", "sequence": { "sequence": 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"header": "tr|A0A8V0YJW8-1|A0A8V0YJW8_CHICK Isoform 1 of SMC5-SMC6 complex localization factor 1 OS=Gallus gallus OX=9031 GN=SLF1 PE=4 SV=1 CANONICAL=A0A8V0YJW8-1" }, "locus": { "chromosome": "Z", "start_pos": 58665290, "end_pos": 58627199, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032074.1", "url": "https://www.ensembl.org/id/ENSGALT00010032074.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018864.1", "url": "https://www.ensembl.org/id/ENSGALP00010018864.1" } ] } }, { "isoform_ac": "A0A8V0YRQ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJW8/entry#A0A8V0YRQ1-1", "sequence": { "sequence": "MAPVGPAAGVRSGVRRAGPPVRRRKRRRESLRDRTAAGLWRPALITGPAALPGGSCDSAAAPGVSAASGGRKRRIQFTGFRKREKKALREMLLKLDCVFVDNKKYRNCTHLIAKKLCKSEKFLAACAAGKWILTKEYIINSAESGRWLDETTYEWGYKIEKDTHYSPQMQSAPKRWRKELKNSGAPGAFHRWKVILAVKEGYEQVAAIRRRIYKILKLPKLMVFCQHTKLTKTSLTCSLLK", "length": 241, "header": "tr|A0A8V0YRQ1-1|A0A8V0YRQ1_CHICK Computationally mapped isoform of SMC5-SMC6 complex localization factor 1 OS=Gallus gallus OX=9031 GN=SLF1 PE=4 SV=1 CANONICAL=A0A8V0YJW8-1" }, "locus": { "chromosome": "Z", "start_pos": 58665290, "end_pos": 58652787, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032062.1", "url": "https://www.ensembl.org/id/ENSGALT00010032062.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018852.1", "url": "https://www.ensembl.org/id/ENSGALP00010018852.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJW8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJW8" } ], "pmid": "" }, { "name": "centrosome", "id": "GO:0005813", "url": 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"https://www.uniprot.org/uniprotkb/A0A8V0YJW8" } ], "pmid": "" }, { "name": "DNA damage response", "id": "GO:0006974", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006974", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJW8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJW8" } ], "pmid": "" }, { "name": "positive regulation of protein-containing complex assembly", "id": "GO:0031334", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031334", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJW8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJW8" } ], "pmid": "" }, { "name": "positive regulation of maintenance of mitotic sister chromatid cohesion", "id": "GO:0034184", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034184", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJW8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJW8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "ubiquitin protein ligase binding", "id": 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"reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YJW8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJW8" }, { "id": "SM00292", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00292" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "BRCT", "eco_id": "ECO_0000259", "start_pos": 67, "end_pos": 145, "start_aa": "Ala", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 107, "end_pos": 109 }, { "start_pos": 287, "end_pos": 289 }, { "start_pos": 331, "end_pos": 333 }, { "start_pos": 621, "end_pos": 623 }, { 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"table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YK43-1", "uniprot_ac": "A0A8V0YK43", "uniprot_id": "A0A8V0YK43_CHICK", "mass": { "chemical_mass": 46272.0, "monoisotopic_mass": 46272.0 }, "refseq": { "ac": "XP_040553566", "name": "proline-rich protein 5 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040553566" }, "gene_names": [ { "name": "PRR5", "type": "recommended", "evidence": [ { "id": "A0A8V0YK43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK43" } ] }, { "name": "PRR5", "type": "synonym", "evidence": [ { "id": "XP_040553566", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040553566" } ] } ], "protein_names": [ { "name": "Proline rich 5", "type": "synonym", "evidence": [ { "id": "A0A8V0YK43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK43/entry#names_and_taxonomy" } ] }, { "name": "proline-rich protein 5 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_040553566", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040553566" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040553566", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040553566" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YK43", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK43" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PRR5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK43", "locus": { "chromosome": "1", "start_pos": 69870057, "end_pos": 69784065, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013360", "url": "https://www.ensembl.org/id/ENSGALG00010013360" } ] } } ], "crossref": [ { "id": "A0A8V0YK43", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YK43", "database": "AlphaFoldDB", "categories": [] }, { "id": "418237", "url": "https://www.ncbi.nlm.nih.gov/gene/418237", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013745", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013745", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016159", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016159", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "HSVCEMS", "url": "https://omabrowser.org/oma/group/HSVCEMS/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YK43", "url": "https://www.orthodb.org/?gene=A0A8V0YK43", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR32428", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR32428", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR32428:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR32428:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF08539", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08539", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-1257604", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1257604", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-389357", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-389357", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-5218920", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5218920", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-6804757", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6804757", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9856530", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9856530", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_040553566", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040553566", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YDR3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDR3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YDR3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDR3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YK43", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK43", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YK43-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK43-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRTLRRLKFMSSPSLSDLGKREQAALDERGTQQRRACSNATWNSIHNGVIAVFQRKGLPDHELYNLNEGVRQLLKTELGSFFTEYLQNQLLTKGMVILRDKIRFYEGQKLLDTLAETWDFFFSDVLPMLQAIFYPVQGKEPSVRQLALLHFRNIITLNIKLEDALSRSRARVPPSIIQMLLILQGVHESKGVTEDYLKLESLIQKVVSPYLGTYGLYSSDGPFTHSSCILEKRFFRRSKSGDILAKNPVVRSKSYNNPLLTPVAEYETEGMAANGTSIRRHSVSEMTSCLELQGYSNLTTIMDNGSKSSMTATKNLLSDQERSSAGPAQCSGKLSTVEQQKGHFHSMDDPHRSFELDRDPSLIPVPSSSPENIVDQILESIDSDSEGIFIDFGRGCSKSSAYNVDVNRQSVL", "length": 412, "header": "tr|A0A8V0YK43-1|A0A8V0YK43_CHICK Isoform 1 of Proline rich 5 OS=Gallus gallus OX=9031 GN=PRR5 PE=3 SV=1 CANONICAL=A0A8V0YK43-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YDR3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK43/entry#A0A8V0YDR3-1", "sequence": { "sequence": "MSSPSLSDLGKREQAALDERGTQQRRACSNATWNRQLLKTELGSFFTEYLQNQLLTKGMVILRDKIRFYEGQKLLDTLAETWDFFFSDVLPMLQAIFYPVQGKEPSVRQLALLHFRNIITLNIKLEDALSRSRARVPPSIIQMLLILQGVHESKGVTEDYLKLESLIQKVVSPYLGTYGLYSSDGPFTHSSCILEKRFFRRSKSGDILAKNPVVRSKSYNNPLLTPVAEYETEGMAANGTSIRRHSVSEMTSCLELQGYSNLTTIMDNGSKSSMTATKNLLSDQERSSAGPAQCSGKLSTVEQQKGHFHSMDDPHRSFELDRDPSLIPVPSSSPENIVDQILESIDSDSEGIFIDFGRGCSKSSAYNVDVNRQSVL", "length": 376, "header": "tr|A0A8V0YDR3-1|A0A8V0YK43_CHICK Computationally mapped isoform of Proline rich 5 OS=Gallus gallus OX=9031 GN=PRR5 PE=3 SV=1 CANONICAL=A0A8V0YK43-1" }, "locus": { "chromosome": "1", "start_pos": 69869143, "end_pos": 69819887, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032166.1", "url": "https://www.ensembl.org/id/ENSGALT00010032166.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018956.1", "url": "https://www.ensembl.org/id/ENSGALP00010018956.1" } ] } }, { "isoform_ac": "A0A8V0YK43-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK43/entry#A0A8V0YK43-1", "sequence": { "sequence": "MRTLRRLKFMSSPSLSDLGKREQAALDERGTQQRRACSNATWNSIHNGVIAVFQRKGLPDHELYNLNEGVRQLLKTELGSFFTEYLQNQLLTKGMVILRDKIRFYEGQKLLDTLAETWDFFFSDVLPMLQAIFYPVQGKEPSVRQLALLHFRNIITLNIKLEDALSRSRARVPPSIIQMLLILQGVHESKGVTEDYLKLESLIQKVVSPYLGTYGLYSSDGPFTHSSCILEKRFFRRSKSGDILAKNPVVRSKSYNNPLLTPVAEYETEGMAANGTSIRRHSVSEMTSCLELQGYSNLTTIMDNGSKSSMTATKNLLSDQERSSAGPAQCSGKLSTVEQQKGHFHSMDDPHRSFELDRDPSLIPVPSSSPENIVDQILESIDSDSEGIFIDFGRGCSKSSAYNVDVNRQSVL", "length": 412, "header": "tr|A0A8V0YK43-1|A0A8V0YK43_CHICK Isoform 1 of Proline rich 5 OS=Gallus gallus OX=9031 GN=PRR5 PE=3 SV=1 CANONICAL=A0A8V0YK43-1" }, "locus": { "chromosome": "1", "start_pos": 69869143, "end_pos": 69819860, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032163.1", "url": "https://www.ensembl.org/id/ENSGALT00010032163.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018953.1", "url": "https://www.ensembl.org/id/ENSGALP00010018953.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-1257604", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1257604", "resource": "Reactome", "description": "PIP3 activates AKT signaling" }, { "id": "R-GGA-389357", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-389357", "resource": "Reactome", "description": "CD28 dependent PI3K/Akt signaling" }, { "id": "R-GGA-5218920", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5218920", "resource": "Reactome", "description": "VEGFR2 mediated vascular permeability" }, { "id": "R-GGA-6804757", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6804757", "resource": "Reactome", "description": "Regulation of TP53 Degradation" }, { "id": "R-GGA-9856530", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9856530", "resource": "Reactome", "description": "High laminar flow shear stress activates signaling by PIEZO1 and PECAM1:CDH5:KDR in endothelial cells" } ], "orthologs": [ { "uniprot_canonical_ac": "P85299-1", "protein_name": "Proline-rich protein 5", "gene_name": "PRR5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRTLRRLKFMSSPSLSDLGKREPAAAADERGTQQRRACANATWNSIHNGVIAVFQRKGLPDQELFSLNEGVRQLLKTELGSFFTEYLQNQLLTKGMVILRDKIRFYEGQKLLDSLAETWDFFFSDVLPMLQAIFYPVQGKEPSVRQLALLHFRNAITLSVKLEDALARAHARVPPAIVQMLLVLQGVHESRGVTEDYLRLETLVQKVVSPYLGTYGLHSSEGPFTHSCILEKRLLRRSRSGDVLAKNPVVRSKSYNTPLLNPVQEHEAEGAAAGGTSIRRHSVSEMTSCPEPQGFSDPPGQGPTGTFRSSPAPHSGPCPSRLYPTTQPPEQGLDPTRSSLPRSSPENLVDQILESVDSDSEGIFIDFGRGRGSGMSDLEGSGGRQSVV", "length": 388 }, "evidence": [ { "id": "A0A8V0YK43", "url": "https://omabrowser.org/oma/group/A0A8V0YK43/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q812A5-1", "protein_name": "Proline-rich protein 5", "gene_name": "Prr5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRTLRRLKFMSSPSLSDLGKREPGAAGTDERGTQQRRACANATWNSIHNGVIAVFQRKGLPDQELFILNEGVRQLLKTELGSFFTEYLQNQLLTKGMVILRDKIRFYEGQKLLDSLAETWDFFFSDVLPTLQAIFYPVQGKEPSVRQLALLHFRNTITLSVKLEDALARSHARVPPAIAQMLLVLQGVHESRGVTEDYLRLETLIQKVVSPYLGTYGLYSNEGPCTHSCILEKRFLRRSRSGDILAKNPVVRSKSYNTPLLNPVAEHEAEGTAASGTSIRRHSVSEMTSCPEPQGFVDTPGQGPSGTFRSSPTPHSGPCPSRLYPPAHSPEQGPGHGSPSTSSPETLVDQILESADSDSEGIFIDFGRGSRSSVSDFEAPGGRPSVV", "length": 387 }, "evidence": [ { "id": "A0A8V0YK43", "url": "https://omabrowser.org/oma/group/A0A8V0YK43/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "TORC2 signaling", "id": "GO:0038203", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038203", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YK43", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK43" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "TORC2 complex", "id": "GO:0031932", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031932", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YK43", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK43" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 274, "end_pos": 276, "annotation": "n_glycosylation_sequon" }, { "start_pos": 297, "end_pos": 299, "annotation": "n_glycosylation_sequon" }, { "start_pos": 304, "end_pos": 306, "annotation": "n_glycosylation_sequon" }, { "start_pos": 39, "end_pos": 41, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 274, "end_pos": 276 }, { "start_pos": 297, "end_pos": 299 }, { "start_pos": 304, "end_pos": 306 }, { "start_pos": 39, "end_pos": 41 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YJI0-1", "uniprot_ac": "A0A8V0YJI0", "uniprot_id": "A0A8V0YJI0_CHICK", "mass": { "chemical_mass": 88307.0, "monoisotopic_mass": 88307.0 }, "refseq": { "ac": "XP_417697", "name": "centrosomal protein of 85 kDa isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_417697" }, "gene_names": [ { "name": "CEP85", "type": "recommended", "evidence": [ { "id": "A0A8V0YJI0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJI0" } ] }, { "name": "CEP85", "type": "synonym", "evidence": [ { "id": "XP_417697", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_417697" } ] } ], "protein_names": [ { "name": "Centrosomal protein 85", "type": "synonym", "evidence": [ { "id": "A0A8V0YJI0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJI0/entry#names_and_taxonomy" } ] }, { "name": "centrosomal protein of 85 kDa isoform X1", "type": "synonym", "evidence": [ { "id": "XP_417697", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_417697" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052554.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_417697.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_417697", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_417697" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJI0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJI0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CEP85", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJI0", "locus": { "chromosome": "23", "start_pos": 594057, "end_pos": 607124, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013365", "url": "https://www.ensembl.org/id/ENSGALG00010013365" } ] } } ], "crossref": [ { "id": "A0A8V0YJI0", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YJI0", "database": "AlphaFoldDB", "categories": [] }, { "id": "419547", "url": "https://www.ncbi.nlm.nih.gov/gene/419547", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR040210", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040210", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR058190", "url": "https://www.ebi.ac.uk/interpro/entry/IPR058190", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "HFSETDW", "url": "https://omabrowser.org/oma/group/HFSETDW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YDS2", "url": "https://www.orthodb.org/?gene=A0A8V0YDS2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YJI0", "url": "https://www.orthodb.org/?gene=A0A8V0YJI0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YK53", "url": "https://www.orthodb.org/?gene=A0A8V0YK53", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YS02", "url": "https://www.orthodb.org/?gene=A0A8V0YS02", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31075", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31075", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31075:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31075:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF24555", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24555", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_417697", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_417697", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YDS2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDS2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YDS2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDS2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJI0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJI0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJI0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJI0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YK53", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK53", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YK53-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK53-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YS02", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YS02", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YS02-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YS02-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAALEEHPDLRLQHSNPSDPSAAQKSHFSETDWKTPMLSVKFQSRTSRCSSAADSGDVGIGTSCSDSTEDFCSSSNGSSFQPIKTQVTIPTAHVMPSTLGASPSKLCSAGEQSCLQSTSKTAVPGSASEHAGLMRNGDFNAGKSSQLPHRDLLRLYGTSGENGFEQSWRPVSDHVRTEDTWKFDTPAIERTLNQSLFLDSLCADPLQRFQKFSSSSGAAEAGGDHYKVLPEIKQVAGANGACESQDRTWPGGSRLMPTGLQTNSFFPKPITSPSRAWMQETCTLHPHERVCELSAWKQQLDNVRLQIEQMQLQNGSACHHPSMYSPSLPTPDPAQWINILNSHENLLKEKELLIDRQRQHISQLEQKVRESELQVHSALLGCPAPCGDVYMLRMQELQRENTFLRAQFTEKTESLSKEKIELERKLAAAEVDAKLIRETLKENMQKYAEDLKKQEERVKGRDKHINNLKKKCQKESEQNRERQQRIETLERYLADLPTLEDHQKQSQKLKESELKSTTLQETVLALETELGDVRAAFREQEMQLETQKHKELELLSTVRSLQDKVQQCVKNAERGPPVQDGEKQKIENDSLKKECDCLRKIVEKQQKKMEQLSLQVKNLEEQVAQEEGTSQALKEEALRRENVLQQLRTAVKELSVQNQDLIEKNLTIQERLRQAELTAQPLPAETARLAQELHCELASCLQDLQSVYSIVTQRAQGKDPNLSLLLGIRSVQYSAKEKDDLLSPDVLAKKLVEVKQLHKEVEDLRTAISDRYAQDMGDNCITQ", "length": 783, "header": "tr|A0A8V0YJI0-1|A0A8V0YJI0_CHICK Isoform 1 of Centrosomal protein 85 OS=Gallus gallus OX=9031 GN=CEP85 PE=4 SV=1 CANONICAL=A0A8V0YJI0-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YDS2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJI0/entry#A0A8V0YDS2-1", "sequence": { "sequence": "MEMGEKTDFCSSSNGSSFQPIKTQVTIPTAHVMPSTLGASPSKLCSAGEQSCLQSTSKTAVPGSASEHAGLMRNGDFNAGKSSQLPHRDLLRLYGTSGENGFEQSWRPVSDHVRTEDTWKFDTPAIERTLNQSLFLDSLCADPLQRFQKFSSSSGAAEAGGDHYKVLPEIKQVAGANGACESQDRTWPGGSRLMPTGLQTNSFFPKPITSPSRAWMQETCTLHPHERVCELSAWKQQLDNVRLQIEQMQLQNGSACHHPSMYSPSLPTPDPAQWINILNSHENLLKEKELLIDRQRQHISQLEQKVRESELQVHSALLGCPAPCGDVYMLRMQELQRENTFLRAQFTEKTESLSKEKIELERKLAAAEVDAKLIRETLKENMQKYAEDLKKQEERVKGRDKHINNLKKKCQKESEQNRERQQRIETLERYLADLPTLEDHQKQSQKLKESELKSTTLQETVLALETELGDVRAAFREQEMQLETQKHKELELLSTVRSLQDKVQQCVKNAERGPPVQDGEKQKIENDSLKKECDCLRKIVEKQQKKMEQLSLQVKNLEEQVAQEEGTSQALKEEALRRENVLQQLRTAVKELSVQNQDLIEKNLTIQERLRQAELTAQPLPAETARLAQELHCELASCLQDLQSVYSIVTQRAQGKDPNLSLLLGIRSVQYSAKEKDDLLSPDVLAKKLVEVKQLHKEVEDLRTAISDRYAQDMGDNCITQ", "length": 721, "header": "tr|A0A8V0YDS2-1|A0A8V0YJI0_CHICK Computationally mapped isoform of Centrosomal protein 85 OS=Gallus gallus OX=9031 GN=CEP85 PE=4 SV=1 CANONICAL=A0A8V0YJI0-1" }, "locus": { "chromosome": "23", "start_pos": 603773, "end_pos": 596249, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032176.1", "url": "https://www.ensembl.org/id/ENSGALT00010032176.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018966.1", "url": "https://www.ensembl.org/id/ENSGALP00010018966.1" } ] } }, { "isoform_ac": "A0A8V0YJI0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJI0/entry#A0A8V0YJI0-1", "sequence": { "sequence": "MAALEEHPDLRLQHSNPSDPSAAQKSHFSETDWKTPMLSVKFQSRTSRCSSAADSGDVGIGTSCSDSTEDFCSSSNGSSFQPIKTQVTIPTAHVMPSTLGASPSKLCSAGEQSCLQSTSKTAVPGSASEHAGLMRNGDFNAGKSSQLPHRDLLRLYGTSGENGFEQSWRPVSDHVRTEDTWKFDTPAIERTLNQSLFLDSLCADPLQRFQKFSSSSGAAEAGGDHYKVLPEIKQVAGANGACESQDRTWPGGSRLMPTGLQTNSFFPKPITSPSRAWMQETCTLHPHERVCELSAWKQQLDNVRLQIEQMQLQNGSACHHPSMYSPSLPTPDPAQWINILNSHENLLKEKELLIDRQRQHISQLEQKVRESELQVHSALLGCPAPCGDVYMLRMQELQRENTFLRAQFTEKTESLSKEKIELERKLAAAEVDAKLIRETLKENMQKYAEDLKKQEERVKGRDKHINNLKKKCQKESEQNRERQQRIETLERYLADLPTLEDHQKQSQKLKESELKSTTLQETVLALETELGDVRAAFREQEMQLETQKHKELELLSTVRSLQDKVQQCVKNAERGPPVQDGEKQKIENDSLKKECDCLRKIVEKQQKKMEQLSLQVKNLEEQVAQEEGTSQALKEEALRRENVLQQLRTAVKELSVQNQDLIEKNLTIQERLRQAELTAQPLPAETARLAQELHCELASCLQDLQSVYSIVTQRAQGKDPNLSLLLGIRSVQYSAKEKDDLLSPDVLAKKLVEVKQLHKEVEDLRTAISDRYAQDMGDNCITQ", "length": 783, "header": "tr|A0A8V0YJI0-1|A0A8V0YJI0_CHICK Isoform 1 of Centrosomal protein 85 OS=Gallus gallus OX=9031 GN=CEP85 PE=4 SV=1 CANONICAL=A0A8V0YJI0-1" }, "locus": { "chromosome": "23", "start_pos": 606846, "end_pos": 596249, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032180.1", "url": "https://www.ensembl.org/id/ENSGALT00010032180.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018970.1", "url": "https://www.ensembl.org/id/ENSGALP00010018970.1" } ] } }, { "isoform_ac": "A0A8V0YK53-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJI0/entry#A0A8V0YK53-1", "sequence": { "sequence": "MVQSRRAVGWAEQDQGLSVQLNFCSSSNGSSFQPIKTQVTIPTAHVMPSTLGASPSKLCSAGEQSCLQSTSKTAVPGSASEHAGLMRNGDFNAGKSSQLPHRDLLRLYGTSGENGFEQSWRPVSDHVRTEDTWKFDTPAIERTLNQSLFLDSLCADPLQRFQKFSSSSGAAEAGGDHYKVLPEIKQVAGANGACESQDRTWPGGSRLMPTGLQTNSFFPKPITSPSRAWMQETCTLHPHERVCELSAWKQQLDNVRLQIEQMQLQNGSACHHPSMYSPSLPTPDPAQWINILNSHENLLKEKELLIDRQRQHISQLEQKVRESELQVHSALLGCPAPCGDVYMLRMQELQRENTFLRAQFTEKTESLSKEKIELERKLAAAEVDAKLIRETLKENMQKYAEDLKKQEERVKGRDKHINNLKKKCQKESEQNRERQQRIETLERYLADLPTLEDHQKQSQKLKESELKSTTLQETVLALETELGDVRAAFREQEMQLETQKHKELELLSTVRSLQDKVQQCVKNAERGPPVQDGEKQKIENDSLKKECDCLRKIVEKQQKKMEQLSLQVKNLEEQVAQEEGTSQALKEEALRRENVLQQLRTAVKELSVQNQDLIEKNLTIQERLRQAELTAQPLPAETARLAQELHCELASCLQDLQSVYSIVTQRAQGKDPNLSLLLGIRSVQYSAKEKDDLLSPDVLAKKLVEVKQLHKEVEDLRTAISDRYAQDMGDNCITQ", "length": 735, "header": "tr|A0A8V0YK53-1|A0A8V0YK53_CHICK Computationally mapped isoform of Centrosomal protein 85 OS=Gallus gallus OX=9031 GN=CEP85 PE=4 SV=1 CANONICAL=A0A8V0YJI0-1" }, "locus": { "chromosome": "23", "start_pos": 603374, "end_pos": 596249, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032172.1", "url": "https://www.ensembl.org/id/ENSGALT00010032172.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018963.1", "url": "https://www.ensembl.org/id/ENSGALP00010018963.1" } ] } }, { "isoform_ac": "A0A8V0YS02-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJI0/entry#A0A8V0YS02-1", "sequence": { "sequence": "MAALEEHPDLRLQHSNPSDFCSSSNGSSFQPIKTQVTIPTAHVMPSTLGASPSKLCSAGEQSCLQSTSKTAVPGSASEHAGLMRNGDFNAGKSSQLPHRDLLRLYGTSGENGFEQSWRPVSDHVRTEDTWKFDTPAIERTLNQSLFLDSLCADPLQRFQKFSSSSGAAEAGGDHYKVLPEIKQVAGANGACESQDRTWPGGSRLMPTGLQTNSFFPKPITSPSRAWMQETCTLHPHERVCELSAWKQQLDNVRLQIEQMQLQNGSACHHPSMYSPSLPTPDPAQWINILNSHENLLKEKELLIDRQRQHISQLEQKVRESELQVHSALLGCPAPCGDVYMLRMQELQRENTFLRAQFTEKTESLSKEKIELERKLAAAEVDAKLIRETLKENMQKYAEDLKKQEERVKGRDKHINNLKKKCQKESEQNRERQQRIETLERYLADLPTLEDHQKQSQKLKESELKSTTLQETVLALETELGDVRAAFREQEMQLETQKHKELELLSTVRSLQDKVQQCVKNAERGPPVQDGEKQKIENDSLKKECDCLRKIVEKQQKKMEQLSLQVKNLEEQVAQEEGTSQALKEEALRRENVLQQLRTAVKELSVQNQDLIEKNLTIQERLRQAELTAQPLPAETARLAQELHCELASCLQDLQSVYSIVTQRAQGKDPNLSLLLGIRSVQYSAKEKDDLLSPDVLAKKLVEVKQLHKEVEDLRTAISDRYAQDMGDNCITQ", "length": 732, "header": "tr|A0A8V0YS02-1|A0A8V0YS02_CHICK Computationally mapped isoform of Centrosomal protein 85 OS=Gallus gallus OX=9031 GN=CEP85 PE=4 SV=1 CANONICAL=A0A8V0YJI0-1" }, "locus": { "chromosome": "23", "start_pos": 606846, "end_pos": 596249, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032182.1", "url": "https://www.ensembl.org/id/ENSGALT00010032182.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018972.1", "url": "https://www.ensembl.org/id/ENSGALP00010018972.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 330, "start_aa": "Thr", "end_pos": 330, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr330", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2JUV7-1", "protein_name": "Centrosomal protein 85", "gene_name": "Cep85", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAMQEKYPSDRSPHTASPGSNVIQKGSSLGTEWQTPVISEAFRSRFSRCSSIADSGDTAIGTSCSDIAEDFCSSSGSPSFQPIKSHITIPTAHVMPSTLGASPAKPSPTPSGPSSAKLPLSGLTEGVGMTRNGDFGAVKRSPGLSRDFMYLPSAAGENGIQQSWFPAVGHEREGEMRKFDVSSMESTLNQPAMLETLYSDPHYRAHFPTPRPDTNKDAYKVLPESKKAPGSGAVFERNGPHASNSGVLPLGLQPAPGLSKSLSSQVWQPSPDPWHPGEQSCELSTCRQQLELIRLQMEQMQLQNGAICHHPAAFTPSLPTLEPAQWISILNSNEHLLKEKELLIDKQRKHISQLEQKVRESELQVHSALLGRPAPFGDVCLLRLQELQRENTFLRAQFAQKTEALSKEKMELEKKLSASEVEIQLIRESLKVTLQKHSEEGKKQEERVKGRDKHINNLKKKCQKESEQNREKQQRIETLERYLADLPTLEDHQKQTEQLKDAELKNTELQGRVAELETMLEDTQAACREKEVQLESLRQREAQFSSARHSFQDKQSLEEASGESLKVEMESQQKECDSLRKIVERQQLKLEQLHSQVQSQKQELAQEEGISQALREEAQRRETALQQMRTAVKELSVQNQDLIEKNLTLQEHLRQAQPGSSSGSPDAAQLAYELHQELASCLQDLQAVCSIVTQRAQGHSPNLSLLLGIHSTPHPGTQLDLQKPDVIRRKLEEVQQLRHDIEDLRTSLSDRYAQDMGENCATQ", "length": 763 }, "evidence": [ { "id": "A0A8V0YJI0", "url": "https://omabrowser.org/oma/group/A0A8V0YJI0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A3Q1M4C0-1", "protein_name": "Centrosomal protein 85", "gene_name": "CEP85", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MQDKYPSERISHATSPGSSVIQKGSSLGTEWQTPVISEAFRSRFSRCSSLADSGDTAIGTSCSDIAEDFCSSSSSPSFQPIKSHVTIPTAHVIPSTLGTSPSKPNSAAGSSTKLPLSGLAESVGMTRNGDLSSMKRSPGLSRDFMYLCGAAGENGVEQSWFPAVGHEREEEARKFDVPNMESTLNQSAMLETLYSDPHYRVYFHNPRTDTNKELYKGLPETKKAPGSGAVCERNGPHPGSSGVLPLGLQPAPGLSKPLPSQVWQPNPDPWHSRERSCELSTCRQQLELIRLQMEQMQLQNGAVCHHPAGFSPSLPTLDPAQWMSILNSNEHLLKEKELLIDKQRKHISQLEQKVRESELQVHSALLGRPAPFGDVCLLRLQELQRENTFLRAQFAQKTEALSKEKIELEKKLSASEVEVQLIRESLRVALQKHSEEGKKQEERVKGRDKHINNLKKKCQKESEQNREKQQRIETLERYLADLPTLEDHQKQSQQLKDSELKSTELQERVTELESLLEETQAACREKEVQLESLRQREADFSSTQHSLQDEQCVEDASGDGPAQQGRGPQVEMESWQKECDSLRKIVERQQQKIDQLHSQVQSLEQEVAQEEGTSQALKEEAQRRETALQQLRTAVKELSVQNQDLIEKNLTLQEHLRQAQSGSPSSSDTAQLAFELHQELASCLQDLQAVCSIVTQRAQGHDPNLSLLLGIHSVHPGTQLDFQKPDVIRRKLEEVQQLRRDIEDLRTTMSDRYAQDMGENCVTQ", "length": 764 }, "evidence": [ { "id": "A0A8V0YJI0", "url": "https://omabrowser.org/oma/group/A0A8V0YJI0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A8C2M334-1", "protein_name": "Centrosomal protein of 85 kDa isoform X1", "gene_name": "Cep85", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAMQEKYPNDRSSHATSPGSNVIQKGSSLGTEWQTPVISEAFRSRFSRCSSIADSGDTAIGTSCSDIAEDFCSSSGSPSFQPIKSHITIPTAHVMPSTLGASPAKPNSTPSGPSSSKLPLSGLAEGVGMTRNGDFGAVKRSPGLSRDFMYLPSAPGENGIQQSWFPAVGHEREGEMRKFDIPSMESTLNQPAMVETLYSDPHYRVHFPTPRSDANKDVYKVLPESKKAPGSGAVFERNGPHASNSGVLPLGLQPAPGLSKSLSSQVWQPSPDPWHPGEQSCELSTCRQQLELIRLQMEQMQLQNGAVCHHPAAFAPLLPTLEPAQWLSILNSNEHLLKEKELLIDKQRKHISQLEQKVRESELQVHSALLGRPAPFGDVCLLRLQELQRENTFLRAQFAQKTEALSKEKMELEKKLSASEVEIQLIRESLKVTLQKHSEEGKKQEERVKGRDKHINNLKKKCQKEAEQNREKQQRIETLERYLADLPTLEDHQKQTEQLKDAELKNTELQERVAELETLVEDTQATCREKEVQLESLRQKEAEFFSARHSLQDKQSVEDTNGEGLEVETESQQKECDSLRKIVERQQLKIEQLHSQVQSLKQELAQEEGISQALKEEAQRRETALQQMRTAVKELSVQNQDLIEKNLTLQEHLRQAQPGSTSSPDTAQLAYELHQELAICLQDLQAVCSIVTQRAQGHNPNLSLLLGIHSTQHPGTQLDLQKPDVVRRKLEEVQQLRHDIEDLRTSLSDRYAQDMGENCATQ", "length": 762 }, "evidence": [ { "id": "A0A8V0YJI0", "url": "https://omabrowser.org/oma/group/A0A8V0YJI0/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q6P2H3-1", "protein_name": "Centrosomal protein of 85 kDa", "gene_name": "CEP85", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAMQEKYPTEGISHVTSPSSDVIQKGSSLGTEWQTPVISEPFRSRFSRCSSVADSGDTAIGTSCSDIAEDFCSSSGSPPFQPIKSHVTIPTAHVMPSTLGTSPAKPNSTPVGPSSSKLPLSGLAESVGMTRNGDLGAMKHSPGLSRDLMYFSGATGENGIEQSWFPAVGHERQEEARKFDIPSMESTLNQSAMMETLYSDPHHRVRFHNPRTSTSKELYRVLPEAKKAPGSGAVFERNGPHSNSSGVLPLGLQPAPGLSKPLPSQVWQPSPDTWHPREQSCELSTCRQQLELIRLQMEQMQLQNGAICHHPAAFGPSLPILEPAQWISILNSNEHLLKEKELLIDKQRKHISQLEQKVRESELQVHSALLGRPAPFGDVCLLRLQELQRENTFLRAQFAQKTEALSREKIDLEKKLSASEVEVQLIRESLKVALQKHSEEVKKQEERVKGRDKHINNLKKKCQKESEQNREKQQRIETLERYLADLPTLEDHQKQSQQLKDSELKSTELQEKVTELESLLEETQAICREKEIQLESLRQREAEFSSAGHSLQDKQSVEETSGEGPEVEMESWQKRYDSLQKIVEKQQQKMDQLRSQVQSLEQEVAQEEGTSQALREEAQRRDSALQQLRTAVKELSVQNQDLIEKNLTLQEHLRQAQPGSPPSPDTAQLALELHQELASCLQDLQAVCSIVTQRAQGHDPNLSLLLGIHSAQHPETQLDLQKPDVIKRKLEEVQQLRRDIEDLRTTMSDRYAQDMGENCVTQ", "length": 762 }, "evidence": [ { "id": "A0A8V0YJI0", "url": "https://omabrowser.org/oma/group/A0A8V0YJI0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8BMK0-1", "protein_name": "Centrosomal protein of 85 kDa", "gene_name": "Cep85", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAMQEKYPNDRSHATSPGSNVIQKGSSLGTEWQTPVISETFRSRFSRCSSIADSGDTAIGTSCSDIAEDFCSSSGSPSFQPIKSHITIPTAHVMPSTLGASPAKPNSAPSGPSSAKLPLSGLTEGVGMTRNGDFGAVKRSPGLARDFMYLPSAAGENGSQQSWFPAVGHEREGEMRKFDVPSMESTLNQPAMLETLYSDPHYRAHFPNPRPDTNKDVYKVLPESKKAPGSGAVFERNGPHASSSGVLPLGLQPAPGLSKSLSSQVWQPSPDPWHPGEQSCELSTCRQQLELIRLQMEQMQLQNGAMCHHPAAFAPLLPTLEPAQWLSILNSNEHLLKEKELLIDKQRKHISQLEQKVRESELQVHSALLGRPAPFGDVCLLRLQELQRENTFLRAQFAQKTEALSKEKMELEKKLSASEVEIQLIRESLKVTLQKHSEEGKKQEERVKGRDKHINNLKKKCQKESEQNREKQQRIETLERYLADLPTLEDHQKQTEQLKDAELKNTELQERVAELETLLEDTQATCREKEVQLESLRQREADLSSARHSFQDKQSVEEANGENLRVDMESQQKECDSLRKMVERQQLKMEQLHSQVQSQKQELAQEEGINQALREEAQRRETALQQMRTAVKELSVQNQDLIEKNLTLQEHLRQAQPGSSSSPDSAQLACELHQELASCLQDLQAVCSIVTQRAQGHNPNLSLLLGIHSTQHPGTQLDLQKPDVIRRKLEEVQQLRHDIEDLRTSLSDRYAQDMGENCATQ", "length": 761 }, "evidence": [ { "id": "A0A8V0YJI0", "url": "https://omabrowser.org/oma/group/A0A8V0YJI0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "regulation of mitotic centrosome separation", "id": "GO:0046602", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046602", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJI0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJI0" } ], "pmid": "" }, { "name": "cell migration", "id": "GO:0016477", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016477", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJI0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJI0" } ], "pmid": "" }, { "name": "centriole replication", "id": "GO:0007099", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007099", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJI0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJI0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 7, "go_terms": [ { "name": "spindle pole", "id": "GO:0000922", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000922", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJI0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJI0" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJI0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJI0" } ], "pmid": "" }, { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJI0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJI0" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJI0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJI0" } ], "pmid": "" }, { "name": "cell cortex", "id": "GO:0005938", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005938", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJI0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJI0" } ], "pmid": "" }, { "name": "centriole", "id": "GO:0005814", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005814", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJI0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJI0" } ], "pmid": "" }, { "name": "pericentriolar material", "id": "GO:0000242", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000242", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJI0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJI0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJI0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJI0" } ], "pmid": "" } ] } ] }, "pro_annotation": 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"tr|A0A8V0YDU1-1|A0A8V0YK88_CHICK Computationally mapped isoform of Regulator of microtubule dynamics protein 1 OS=Gallus gallus OX=9031 GN=RMDN1 PE=1 SV=1 CANONICAL=A0A8V0YK88-1" }, "locus": { "chromosome": "2", "start_pos": 122733791, "end_pos": 122721598, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032195.1", "url": "https://www.ensembl.org/id/ENSGALT00010032195.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018986.1", "url": "https://www.ensembl.org/id/ENSGALP00010018986.1" } ] } }, { "isoform_ac": "A0A8V0YK83-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK88/entry#A0A8V0YK83-1", "sequence": { "sequence": "LQGAGCPGPTPLQGTAAPRGREAAPRAEGEVLRKSLRRGVALSTGSFVLCEALRLISGSAEVHASFKVAEVIEQADYLYGSGETEKLYQLLVQHKNSEDAELLWRLARASRDLAQLSITSAEEKRQLAYDSLEYAKRALEKNEANSAAHKWYAICLSDVGDYEGIKVKIGNAFVIKEHFERAIELNPKDATSVHLMGVWCYSFAELPWYQRKIAAMLFATPPTSTYEEALRYFHMAEEADPNFYSKNLLFLGKTYLKLNNKKMALLWLSKAKEYPAHTEEDKQVQKEALELLNSI", "length": 295, "header": "tr|A0A8V0YK83-1|A0A8V0YK83_CHICK Computationally mapped isoform of Regulator of microtubule dynamics protein 1 OS=Gallus gallus OX=9031 GN=RMDN1 PE=1 SV=1 CANONICAL=A0A8V0YK88-1" }, "locus": { "chromosome": "2", "start_pos": 122734350, "end_pos": 122721598, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032203.1", "url": "https://www.ensembl.org/id/ENSGALT00010032203.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018993.1", "url": "https://www.ensembl.org/id/ENSGALP00010018993.1" } ] } }, { "isoform_ac": "A0A8V0YK88-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK88/entry#A0A8V0YK88-1", "sequence": { "sequence": "EEAPGTRAFTHGHSRSSGRGGAEPRPWVPLAAVPVEPRPNRKVLRKSLRRGVALSTGSFVLCEALRLISGSAEVHASFKVAEVIEQADYLYGSGETEKLYQLLVQHKNSEDAELLWRLARASRDLAQLSITSAEEKRQLAYDSLEYAKRALEKNEANSAAHKWYAICLSDVGDYEGIKVKIGNAFVIKEHFERAIELNPKDATSVHLMGVWCYSFAELPWYQRKIAAMLFATPPTSTYEEALRYFHMAEEADPNFYSKNLLFLGKTYLKLNNKKMALLWLSKAKEYPAHTEEDKQVQKEALELLNSI", "length": 307, "header": "tr|A0A8V0YK88-1|A0A8V0YK88_CHICK Isoform 1 of Regulator of microtubule dynamics protein 1 OS=Gallus gallus OX=9031 GN=RMDN1 PE=1 SV=1 CANONICAL=A0A8V0YK88-1" }, "locus": { "chromosome": "2", "start_pos": 122734530, "end_pos": 122721598, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032208.1", "url": "https://www.ensembl.org/id/ENSGALT00010032208.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018998.1", "url": "https://www.ensembl.org/id/ENSGALP00010018998.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:420213", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420213", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YK88", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK88" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YK88", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK88" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YK88", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK88" } ], "pmid": "" }, { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YK88", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK88" } ], "pmid": "" }, { "name": "spindle microtubule", "id": "GO:0005876", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005876", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YK88", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK88" } ], "pmid": "" }, { "name": "mitotic spindle pole", "id": "GO:0097431", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097431", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YK88", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK88" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "microtubule binding", "id": "GO:0008017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008017", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YK88", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK88" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YM10-1", "uniprot_ac": "A0A8V0YM10", "uniprot_id": "A0A8V0YM10_CHICK", "mass": { "chemical_mass": 46702.0, "monoisotopic_mass": 46702.0 }, "refseq": { "ac": "NP_001181925", "name": "trafficking protein particle complex subunit 13 isoform 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001181925" }, "gene_names": [ { "name": "TRAPPC13", "type": "recommended", "evidence": [ { "id": "A0A8V0YM10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM10" } ] }, { "name": "C5orf44", "type": "synonym", "evidence": [ { "id": "NP_001181925", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001181925" } ] }, { "name": "CZH5ORF44", "type": "synonym", "evidence": [ { "id": "NP_001181925", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001181925" } ] }, { "name": "TRAPPC13", "type": "synonym", "evidence": [ { "id": "NP_001181925", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001181925" } ] }, { "name": "Trs65-related", "type": "synonym", "evidence": [ { "id": "NP_001181925", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001181925" } ] } ], "protein_names": [ { "name": "Trafficking protein particle complex subunit 13", "type": "recommended", "evidence": [ { "id": "A0A8V0YM10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM10/entry#names_and_taxonomy" } ] }, { "name": "UPF0533 protein C5orf44", "type": "synonym", "evidence": [ { "id": "NP_001181925", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001181925" } ] }, { "name": "trafficking protein particle complex subunit 13 isoform 1", "type": "synonym", "evidence": [ { "id": "NP_001181925", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001181925" } ] }, { "name": "trafficking protein particle complex subunit 13", "type": "synonym", "evidence": [ { "id": "NP_001181925", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001181925" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000089.1. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001181925", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001181925" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YM10", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM10" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TRAPPC13", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM10", "locus": { "chromosome": "Z", "start_pos": 21182493, "end_pos": 21157775, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012309", "url": "https://www.ensembl.org/id/ENSGALG00010012309" } ] } } ], "crossref": [ { "id": "A0A8V0YM10", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YM10", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000014767", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000014767", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "427165", "url": "https://www.ncbi.nlm.nih.gov/gene/427165", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR010378", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010378", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055427", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055427", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055428", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055428", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055429", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055429", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "YLCVHNG", "url": "https://omabrowser.org/oma/group/YLCVHNG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1L1RS53", "url": "https://www.orthodb.org/?gene=A0A1L1RS53", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q3ANP4", "url": "https://www.orthodb.org/?gene=A0A3Q3ANP4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YDW3", "url": "https://www.orthodb.org/?gene=A0A8V0YDW3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YF41", "url": "https://www.orthodb.org/?gene=A0A8V0YF41", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YM10", "url": "https://www.orthodb.org/?gene=A0A8V0YM10", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1C0E0", "url": "https://www.orthodb.org/?gene=E1C0E0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13134", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13134", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13134:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13134:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF06159", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06159", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23643", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23643", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23647", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23647", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001181925", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001181925", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1L1RS53", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RS53", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1L1RS53-1", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RS53-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q3ANP4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3ANP4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q3ANP4-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3ANP4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YDW3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDW3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YDW3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDW3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YF41", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF41", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YF41-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF41-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YM10", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM10", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YM10-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM10-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C0E0", "url": "https://www.uniprot.org/uniprotkb/E1C0E0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C0E0-1", "url": "https://www.uniprot.org/uniprotkb/E1C0E0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDVNQPKQEHLLALKVMRLTKPTLFTNIPVTCEERDLPGNLFNQLMKDDPSTVKGAEALMLGEMLTLPQNFGNIFLGETFSSYISVHNDSNQVVKDILVKADLQTSSQRLNLSASTAAVAELKPDCCIDDVIHHEVKEIGTHILVCAVSYTTQAGEKMYFRKFFKFQVLKPLDVKTKFYNAESDLSSVTDEVFLEAQIQNITTSPMFMEKVSLEPSIMYNVAELNTVDSAGESESTFGSRTYLQPMDTRQYLYCLKPKQEFAEKAGVIKGVTVIGKLDIVWKTNLGERGRLQTSQLQRMAPGYGDVRLSLETIPDTVNLEEPFDITCKITNCSSERTMDLVLEMCNTNSIHWCGVSGRQLGKLHPSSSLRLALTLLSSVQGLQSVSGLRLTDTFLKRTYEYDDIAQVCVVSSKVKQES", "length": 418, "header": "tr|A0A8V0YM10-1|A0A8V0YM10_CHICK Isoform 1 of Trafficking protein particle complex subunit 13 OS=Gallus gallus OX=9031 GN=TRAPPC13 PE=1 SV=1 CANONICAL=A0A8V0YM10-1" }, "isoforms": [ { "isoform_ac": "A0A1L1RS53-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM10/entry#A0A1L1RS53-1", "sequence": { "sequence": "MDVNQPKQEHLLALKVMRLTKPTLFTNIPVTCEERDLPGNLFNQLMKDDPSTVKGAEALMLGEMLTLPQNFGNIFLGETFSSYISVHNDSNQVVKDILVKADLQTSSQRLNLSASTAAVAELKPDCCIDDVIHHEVKEIGTHILVCAVSYTTQAGEKMYFRKFFKFQVLKPLDVKTKFYNAETDEVFLEAQIQNITTSPMFMEKVSLEPSIMYNVAELNTVDSAGESESTFGSRTYLQPMDTRQYLYCLKPKQEFAEKAGVIKGVTVIGKLDIVWKTNLGERGRLQTSQLQRMAPGYGDVRLSLETIPDTVNLEEPFDITCKITNCSSERTMDLVLEMCNTNSIHWCGVSGRQLGKLHPSSSLRLALTLLSSVQGLQSVSGLRLTDTFLKRTYEYDDIAQVCVVSSKVKQES", "length": 412, "header": "tr|A0A1L1RS53-1|A0A1L1RS53_CHICK Computationally mapped isoform of Trafficking protein particle complex subunit 13 OS=Gallus gallus OX=9031 GN=TRAPPC13 PE=1 SV=2 CANONICAL=A0A8V0YM10-1" }, "locus": { "chromosome": "Z", "start_pos": 21182078, "end_pos": 21157845, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029488.1", "url": "https://www.ensembl.org/id/ENSGALT00010029488.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017140.1", "url": "https://www.ensembl.org/id/ENSGALP00010017140.1" } ] } }, { "isoform_ac": "A0A3Q3ANP4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM10/entry#A0A3Q3ANP4-1", "sequence": { "sequence": "MILTVLLGYTTAGELNSMMRLTKPTLFTNIPVTCEERDLPGNLFNQLMKDDPSTVKGAEALMLGEMLTLPQNFGNIFLGETFSSYISVHNDSNQVVKDILVKADLQTSSQRLNLSASTAAVAELKPDCCIDDVIHHEVKEIGTHILVCAVSYTTQAGEKMYFRKFFKFQVLKPLDVKTKFYNAETDEVFLEAQIQNITTSPMFMEKVSLEPSIMYNVAELNTVDSAGESESTFGSRTYLQPMDTRQYLYCLKPKQEFAEKAGVIKGVTVIGKLDIVWKTNLGERGRLQTSQLQRMAPGYGDVRLSLETIPDTVNLEEPFDITCKITNCSSERTMDLVLEMCNTNSIHWCGVSGRQLGKLHPSSSLRLALTLLSSVQGLQSVSGLRLTDTFLKRTYEYDDIAQVCVVSSKVKQES", "length": 414, "header": "tr|A0A3Q3ANP4-1|A0A3Q3ANP4_CHICK Computationally mapped isoform of Trafficking protein particle complex subunit 13 OS=Gallus gallus OX=9031 GN=TRAPPC13 PE=1 SV=1 CANONICAL=A0A8V0YM10-1" }, "locus": { "chromosome": "Z", "start_pos": 21182078, "end_pos": 21162868, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029473.1", "url": "https://www.ensembl.org/id/ENSGALT00010029473.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017130.1", "url": "https://www.ensembl.org/id/ENSGALP00010017130.1" } ] } }, { "isoform_ac": "A0A8V0YDW3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM10/entry#A0A8V0YDW3-1", "sequence": { "sequence": "MDVNQPKQEHLLALKVMRLTKPTLFTNIPVTCEERDLPGNLFNQLMKDDPSTVKGAEALMLGEMLTLPQNFGNIFLGETFSSYISVHNDSNQVVKDILVKADLQTSSQRLNLSASTAAVAELKPDCCIDDVIHHEVKEIGTHILVCAVSYTTQAGEKMYFRKFFKFQVLKPLDVKTKFYNAEMKILGANISHVQSCTGDSPRFSLLYMNSM", "length": 211, "header": "tr|A0A8V0YDW3-1|A0A8V0YM10_CHICK Computationally mapped isoform of Trafficking protein particle complex subunit 13 OS=Gallus gallus OX=9031 GN=TRAPPC13 PE=1 SV=1 CANONICAL=A0A8V0YM10-1" }, "locus": { "chromosome": "Z", "start_pos": 21171469, "end_pos": 21157845, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029468.1", "url": "https://www.ensembl.org/id/ENSGALT00010029468.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017125.1", "url": "https://www.ensembl.org/id/ENSGALP00010017125.1" } ] } }, { "isoform_ac": "A0A8V0YF41-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM10/entry#A0A8V0YF41-1", "sequence": { "sequence": "MDVNQPKQEHLLALKGNLFNQLMKDDPSTVKGAEALMLGEMLTLPQNFGNIFLGETFSSYISVHNDSNQVVKDILVKADLQTSSQRLNLSASTAAVAELKPDCCIDDVIHHEVKEIGTHILVCAVSYTTQAGEKMYFRKFFKFQVLKPLDVKTKFYNAESDLSSVTDEVFLEAQIQNITTSPMFMEKVSLEPSIMYNVAELNTVDSAGESESTFGSRTYLQPMDTRQYLYCLKPKQEFAEKAGVIKGVTVIGKLDIVWKTNLGERGRLQTSQLQRMAPGYGDVRLSLETIPDTVNLEEPFDITCKITNCSSERTMDLVLEMCNTNSIHWCGVSGRQLGKLHPSSSLRLALTLLSSVQGLQSVSGLRLTDTFLKRTYEYDDIAQVCVVSSKVKQES", "length": 395, "header": "tr|A0A8V0YF41-1|A0A8V0YM10_CHICK Computationally mapped isoform of Trafficking protein particle complex subunit 13 OS=Gallus gallus OX=9031 GN=TRAPPC13 PE=1 SV=1 CANONICAL=A0A8V0YM10-1" }, "locus": { "chromosome": "Z", "start_pos": 21182078, "end_pos": 21157845, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029476.1", "url": "https://www.ensembl.org/id/ENSGALT00010029476.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017133.1", "url": "https://www.ensembl.org/id/ENSGALP00010017133.1" } ] } }, { "isoform_ac": "A0A8V0YM10-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM10/entry#A0A8V0YM10-1", "sequence": { "sequence": "MDVNQPKQEHLLALKVMRLTKPTLFTNIPVTCEERDLPGNLFNQLMKDDPSTVKGAEALMLGEMLTLPQNFGNIFLGETFSSYISVHNDSNQVVKDILVKADLQTSSQRLNLSASTAAVAELKPDCCIDDVIHHEVKEIGTHILVCAVSYTTQAGEKMYFRKFFKFQVLKPLDVKTKFYNAESDLSSVTDEVFLEAQIQNITTSPMFMEKVSLEPSIMYNVAELNTVDSAGESESTFGSRTYLQPMDTRQYLYCLKPKQEFAEKAGVIKGVTVIGKLDIVWKTNLGERGRLQTSQLQRMAPGYGDVRLSLETIPDTVNLEEPFDITCKITNCSSERTMDLVLEMCNTNSIHWCGVSGRQLGKLHPSSSLRLALTLLSSVQGLQSVSGLRLTDTFLKRTYEYDDIAQVCVVSSKVKQES", "length": 418, "header": "tr|A0A8V0YM10-1|A0A8V0YM10_CHICK Isoform 1 of Trafficking protein particle complex subunit 13 OS=Gallus gallus OX=9031 GN=TRAPPC13 PE=1 SV=1 CANONICAL=A0A8V0YM10-1" }, "locus": { "chromosome": "Z", "start_pos": 21182078, "end_pos": 21157845, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029485.1", "url": "https://www.ensembl.org/id/ENSGALT00010029485.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017137.1", "url": "https://www.ensembl.org/id/ENSGALP00010017137.1" } ] } }, { "isoform_ac": "E1C0E0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM10/entry#E1C0E0-1", "sequence": { "sequence": "MDVNQPKQEHLLALKVMRLTKPTLFTNIPVTCEERDLPGNLFNQLMKDDPSTVKGAEALMLGEMLTLPQNFGNIFLGETFSSYISVHNDSNQVVKDILVKADLQTSSQRLNLSASTAAVAELKPDCCIDDVIHHEVKEIGTHILVCAVSYTTQAGEKMYFRKFFKFQTDEVFLEAQIQNITTSPMFMEKVSLEPSIMYNVAELNTVDSAGESESTFGSRTYLQPMDTRQYLYCLKPKQEFAEKAGVIKGVTVIGKLDIVWKTNLGERGRLQTSQLQRMAPGYGDVRLSLETIPDTVNLEEPFDITCKITNCSSERTMDLVLEMCNTNSIHWCGVSGRQLGKLHPSSSLRLALTLLSSVQGLQSVSGLRLTDTFLKRTYEYDDIAQVCVVSSKVKQES", "length": 397, "header": "tr|E1C0E0-1|E1C0E0_CHICK Computationally mapped isoform of Trafficking protein particle complex subunit 13 OS=Gallus gallus OX=9031 GN=TRAPPC13 PE=1 SV=3 CANONICAL=A0A8V0YM10-1" }, "locus": { "chromosome": "Z", "start_pos": 21182078, "end_pos": 21157845, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029480.1", "url": "https://www.ensembl.org/id/ENSGALT00010029480.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017134.1", "url": "https://www.ensembl.org/id/ENSGALP00010017134.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A5PLN9-1", "protein_name": "Trafficking protein particle complex subunit 13", "gene_name": "TRAPPC13", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEVNPPKQEHLLALKVMRLTKPTLFTNIPVTCEEKDLPGDLFNQLMRDDPSTVNGAEVLMLGEMLTLPQNFGNIFLGETFSSYISVHNDSNQVVKDILVKADLQTSSQRLNLSASNAAVAELKPDCCIDDVIHHEVKEIGTHILVCAVSYTTQAGEKMYFRKFFKFQVLKPLDVKTKFYNAESDLSSVTDEVFLEAQIQNMTTSPMFMEKVSLEPSIMYNVTELNSVSQAGECVSTFGSRAYLQPMDTRQYLYCLKPKNEFAEKAGIIKGVTVIGKLDIVWKTNLGERGRLQTSQLQRMAPGYGDVRLSLEAIPDTVNLEEPFHITCKITNCSERTMDLVLEMCNTNSIHWCGISGRQLGKLHPSSSLCLALTLLSSVQGLQSISGLRLTDTFLKRTYEYDDIAQVCVVSSAIKVES", "length": 417 }, "evidence": [ { "id": "A0A8V0YM10", "url": "https://omabrowser.org/oma/group/A0A8V0YM10/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A7MB76-1", "protein_name": "Trafficking protein particle complex subunit 13", "gene_name": "TRAPPC13", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MEVNPPKQEHLLALKVMRLTKPTLFTNIPVTCEEKDLPGDLFNQLMRDDPSTVNGAEILMLGEMLTLPQNFGNIFLGETFSSYISVHNDSNQVVKDILVKADLQTSSQRLNLSASNAAVAELKPDCCIDDVIHHEVKEIGTHILVCAVSYTTQSGEKMYFRKFFKFQVLKPLDVKTKFYNAESDLSSVTDEVFLEAQIQNITTSPMFMEKVSLEPSIMYNVAELNSVNQAGECVTTFGSRAYLQPMDTRQYLYCLKPKKEFAEKAGIIKGVTVIGKLDIVWKTNLGERGRLQTSQLQRMAPGYGDVRLSLEAIPDTVNLEEPFHITCKITNCSERTMDLVLEMCNTNSIHWCGISGRQLGKLHPSSSLCLALTLLSSVQGLQSVSGLRLTDTFLKRTYEYDDIAQVCVVSSAIKVES", "length": 417 }, "evidence": [ { "id": "A0A8V0YM10", "url": "https://omabrowser.org/oma/group/A0A8V0YM10/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "O82263-1", "protein_name": "Trafficking protein particle complex subunit-like protein", "gene_name": "TRAPPC13", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSATQTQTHGPHSLAFRVMRLCKPSFHVDPPLRIDPFDLLAGEDFSDDPSSASLFRRHVSSADAVDSDLSYRNRFLLNHPTDPIGLSGLLLLPQSFGAIYLGETFCSYISVNNSSTSEVRDVTIKAEIQTERQRILLLDTSKSPVESIRTGGRYDFIVEHDVKELGAHTLVCSALYNDADGERKYLPQFFKFVVANPLSVRTKVRVVKETTFLEACIENHTKANLFMDQVDFEPAKQWSAVRLQNEDSTEDPPTSGLSGLIPKPPVIIRSGGGIHNYLYKLNPSADVSGQTKFQGSNILGKFQITWRTNLGEPGRLQTQQILGAPVSRKEINMRVVEVPAVIHLNRPFRAYLNLTNQTDRQLGPFEVSLSQDETQLEKPVGINGLQTLMLPRIEAFGSNDFQLNLIASKLGVQKIAGITALDTREKKTYELVPDMEIFVETD", "length": 442 }, "evidence": [ { "id": "A0A8V0YM10", "url": "https://omabrowser.org/oma/group/A0A8V0YM10/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q3TIR1-1", "protein_name": "Trafficking protein particle complex subunit 13", "gene_name": "Trappc13", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEVNPPKQEHLLALKVMRLTKPTLFTNIPVTCEEKDLPGDLFNQLMKDDPSTVNGAEILMLGEMLTLPQNFGNIFLGETFSSYISVHNDSNQVVKDILVKADLQTSSQRLNLSASNAAVAELKPDCCIDDVIHHEVKEIGTHILVCAVSYTTQGGEKMYFRKFFKFQVLKPLDVKTKFYNAESDLSSVTDEVFLEAQIQNITTSPMFMEKVSLEPSIMYNVTELNSVTQAGECISTFGSRGYLQPMDTRQYLYCLKPKKEFAEKAGIIKGVTVIGKLDIVWKTNLGERGRLQTSQLQRMAPGYGDVRLSLEAIPDTVNLEEPFHITCKITNCSERMMDLVLEMCNTNSIHWCGISGRQLGKLHPSSSLCLALTLLSSVQGLQSVSGLRLTDTFLKRTYEYDDIAQVCVVSAAVEVEA", "length": 417 }, "evidence": [ { "id": "A0A8V0YM10", "url": "https://omabrowser.org/oma/group/A0A8V0YM10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q55EX6-1", "protein_name": "Trafficking protein particle complex subunit 13 homolog", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKENHLLNLKVMRLSKPNIPTINPILCEKQDLPYETMSTSIDSTSLSMGSVNSSGSNDNNQLIGNNGNPINMEGLGVTSMLQLQSGVIYLGEMFCCYISLNNHSPYQVRNVFLKVELQTTSSRIPLLDSEQQSVPTFNPGFSSDFVVQREVKESGVNILVCAVNYTTPEGEQKKFRKYFKFQVLNPLVLKTRIHNLPNVVFLEACLENATQGSLFIESILFEPIEHFNSKDISFENSLDDNNNLDNNNNNLENDNNLNNLEFKLNEKGLIENTDELLENIKLTTSDNIVFLKQGCSRQYLFQITPKDIENVESKNSLPLGRLDITWRSYFGEIGRLKTAAIQRKLNQEDIECSLINIPDKIKLEKPFSVIAKLSNKSNRILYPQFMLVRNKMDGIKINSHLPKLDPIQPNSIIQVEIEMFPLKPGMQQIIGLAIKLLDPPVIGITPTTSSSQQQQPISKPTLGQVLQQTQQSQIQQQQQQQNQQLQPPKNFYEFNAVDTWVEFADSKLVDI", "length": 511 }, "evidence": [ { "id": "A0A8V0YM10", "url": "https://omabrowser.org/oma/group/A0A8V0YM10/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q5M887-1", "protein_name": "Trafficking protein particle complex subunit 13", "gene_name": "Trappc13", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEVNPPKQEHLLALKVMRLTKPTLFTNIPVTCEEKDLPGDLFNQLMKDDPSTVNGAEILMLGEMLTLPQNFGNIFLGETFSSYISVHNDSNQVVKDILVKADLQTSSQRLNLSASNAAVAELKPDCCIDDVIHHEVKEIGTHILVCAVSYTTQGGEKMYFRKFFKFQVLKPLDVKTKFYNAESDLSSVTDEVFLEAQIQNITTSPMFMEKVSLEPSIMYNVTELNSVNQAGECVSTFGSRGYLQPMDTRQYLYCLKPKKEFAEKAGIIKGVTVIGKLDIVWKTNLGERGRLQTSQLQRMAPGYGDVRLSLEAIPDTVNLEEPFHITCKITNCSSERTMDLVLEMCNTTSIHWCGISGRQLGKLHPSSSLCLALTLLSSVQGLQSVSGLRLTDTFLKRTYEYDDIAQVCVVSAAVEVEA", "length": 418 }, "evidence": [ { "id": "A0A8V0YM10", "url": "https://omabrowser.org/oma/group/A0A8V0YM10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6PBY7-1", "protein_name": "Trafficking protein particle complex subunit 13", "gene_name": "trappc13", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDVNQAKQEHLLALKVMRLTKPTLFTNMPVTCEDRDLPGDLFLRLMKDDPSTVKGAETLILGEMLTLPQNFGNIFLGETFSSYISVHNDSSQVVKDILVKADLQTSSQRLNLSASNSAVSELKPECCIDDVIHHEVKEIGTHILVCAVSYTTQTGEKLYFRKFFKFQVLKPLDVKTKFYNAETDEVFLEAQIQNITTSPMFMEKVSLEPSMMYNVTELNNVASGDESSESTFGKMSYLQPLDTRQYLYCLKPKPEFAEKAGVIKGVTVIGKLDIVWKTNLGERGRLQTSQLQRMAPGYGDVRLSLEFIPDTVDLEEPFDITCKITNCSERTMDLLLEMCNTRSVHWCGVSGRQLGKLSPSASLSIPLKLLSSVQGLQSISGLRLTDTFLKRTYEYDDIAQVCVVCPYTSPES", "length": 412 }, "evidence": [ { "id": "A0A8V0YM10", "url": "https://omabrowser.org/oma/group/A0A8V0YM10/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "TRAPPIII protein complex", "id": "GO:1990072", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990072", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YM10", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM10" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 111, "end_pos": 113, "annotation": "n_glycosylation_sequon" }, { "start_pos": 200, "end_pos": 202, "annotation": "n_glycosylation_sequon" }, { "start_pos": 331, "end_pos": 333, "annotation": "n_glycosylation_sequon" }, { "start_pos": 88, "end_pos": 90, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YM10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM10" }, { "id": "PF23643", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23643" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Trafficking protein particle complex subunit 13 C-terminal", "eco_id": "ECO_0000259", "start_pos": 314, "end_pos": 409, "start_aa": "Pro", "end_aa": "Val", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0YM10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM10" }, { "id": "PF06159", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06159" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Trafficking protein particle complex subunit 13 N-terminal", "eco_id": "ECO_0000259", "start_pos": 10, "end_pos": 168, "start_aa": "His", "end_aa": "Val", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0YM10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM10" }, { "id": "PF23647", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23647" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Trafficking protein particle complex subunit 13 middle", "eco_id": "ECO_0000259", "start_pos": 172, "end_pos": 301, "start_aa": "Leu", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 111, "end_pos": 113 }, { "start_pos": 200, "end_pos": 202 }, { "start_pos": 331, "end_pos": 333 }, { "start_pos": 88, "end_pos": 90 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YIL0-1", "uniprot_ac": "A0A8V0YIL0", "uniprot_id": "A0A8V0YIL0_CHICK", "mass": { "chemical_mass": 79500.0, "monoisotopic_mass": 79500.0 }, "refseq": { "ac": "XP_046784528", "name": "myosin light chain kinase family member 4 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046784528" }, "gene_names": [ { "name": "MYLK4", "type": "recommended", "evidence": [ { "id": "A0A8V0YIL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIL0" } ] }, { "name": "MYLK4", "type": "synonym", "evidence": [ { "id": "XP_046784528", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046784528" } ] } ], "protein_names": [ { "name": "Myosin light chain kinase family member 4", "type": "synonym", "evidence": [ { "id": "A0A8V0YIL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIL0/entry#names_and_taxonomy" } ] }, { "name": "myosin light chain kinase family member 4 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_046784528", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046784528" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052533.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_046784528", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046784528" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIL0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIL0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MYLK4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIL0", "locus": { "chromosome": "2", "start_pos": 67260462, "end_pos": 67341317, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010011578", "url": "https://www.ensembl.org/id/ENSGALG00010011578" } ] } } ], "crossref": [ { "id": "A0A8V0YIL0", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YIL0", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd14193", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14193", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "420893", "url": "https://www.ncbi.nlm.nih.gov/gene/420893", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000719", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000719", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008271", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008271", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011009", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011009", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017441", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017441", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:420893", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420893", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PNIPREC", "url": "https://omabrowser.org/oma/group/PNIPREC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y5G8", "url": "https://www.orthodb.org/?gene=A0A8V0Y5G8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YBN7", "url": "https://www.orthodb.org/?gene=A0A8V0YBN7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YDX1", "url": "https://www.orthodb.org/?gene=A0A8V0YDX1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YIL0", "url": "https://www.orthodb.org/?gene=A0A8V0YIL0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24347", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24347", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00069", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00069", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_046784528", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046784528", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Y5G8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5G8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y5G8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5G8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YBN7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBN7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YBN7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBN7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YDX1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDX1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YDX1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDX1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YIL0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIL0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YIL0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIL0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTTSSRQSSSTSMVNNLAKMFDPNALQNQGPDNTMEPLKIRRVVSSDVSTESFNVMDMKFAFLEQKIDKLLMLQDNVLKKLNSVSQEIYCIEKDIEIVKAETSEPGLKMERNKNLRNNQMKRLCLKMKKSLSDINRNAEQQVKRLDGLEQSVSAIQKLVGPLAEKVKALIIHHSSGKHHILKRKLRKAGDYTKAAGRGFGMQIFSETTADALLKTRSEKVVKEKLHLSETGTNSTQEEEPPDSAEGVIQNSQSCCHEEEVDKLNKENAERESTVLLQTDSPEFHSEETEEKEEIAFESCYRRSSVQQEDDAVYDACQRITGQEIERESPADEETKEEHQVPGAEEQEERMNEGEGVDSKNEKEDEEPSAPSQNEDEAGQSHDQEAPEGMCKGCGKDDTSPPAPFDHRIVSAKRVGISSYYNVNRNEILGGGRFGQVHKCEEKATGLKLAAKIIKARGDKEKNEVKNEISVMNQLNHVNLIQLYDAFESKNDIVLVMEYVEGGELFDRIIDENCNLTEMDTISFIKQICEGIQYMHQMYILHLDLKPENILCVNRSANQIKIIDFGLARRYKPREKLRVNFGTPEFLAPEVVNYEFVSFPTDMWSVGVIAYMLLSGLSPFLGEDDNETLNNILACSWDFEDEEFQGVSEQAKDFISKLLIKEKCWRISATAALKHPWLSDHKLHCRLQKKVKGDSESQAPSDP", "length": 702, "header": "tr|A0A8V0YIL0-1|A0A8V0YIL0_CHICK Isoform 1 of Myosin light chain kinase family member 4 OS=Gallus gallus OX=9031 GN=MYLK4 PE=3 SV=1 CANONICAL=A0A8V0YIL0-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Y5G8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIL0/entry#A0A8V0Y5G8-1", "sequence": { "sequence": "MTTSSRQSSSTSMVNNLAKMFDPNALQNQGPDNTMEPLKIRRVVSSDVSTESFNVMDMKFAFLEQKIDKLLMLQDNVLKKLNSVSQEIYCIEKDIEIVKAETSEPGLKMERNKNLRNNQMKRLCLKMKKSLSDINRNAEQQVKRLDGLEQSVSAIQKLVGPLAEKVKALIIHHSSGKHHILKRKLRKAGDYTKAAGRGFGMQIFSETTADALLKTRSEKVVKEKLHLSETGTNSTQEEEPPDSAEGVIQNSQSCCHEEEVDKLNKENAERESTVLLQTDSPEFHSEETEEKEEIAFESCYRRSSVQQEDDAVYDACQRITGQEIERESPADEETKEEHQVPGAEEQEERMNEGEGVDSKNEKEDEEPSAPSQNEDEAGQSHDQEAPEGMCKGCGKDDTSPPAPFDHRIVSAKRVGISSYYNVNRNEILGGGRFGQVHKCEEKATGLKLAAKIIKARGDKEKNEVKNEISVMNQLNHVNLIQLYDAFESKNDIVLVMEYVEGGELFDRIIDENCNLTEMDTISFIKQICEGIQYMHQMYILHLDLKPENILCVNRSANQIKIIDFGLARRYKPREKLRVNFGTPEFLAPEVVNYEFVSFPTDMWSVGVIAYMLLSGLSPFLGEDDNETLNNILACSWDFEDEEFQGVSEQAKDFISKLLIKEKCWRISATAALKHPWLSDHKLHCRLQKVKGDSESQAPSDP", "length": 701, "header": "tr|A0A8V0Y5G8-1|A0A8V0Y5G8_CHICK Computationally mapped isoform of Myosin light chain kinase family member 4 OS=Gallus gallus OX=9031 GN=MYLK4 PE=3 SV=1 CANONICAL=A0A8V0YIL0-1" }, "locus": { "chromosome": "2", "start_pos": 67289976, "end_pos": 67264076, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027706.1", "url": "https://www.ensembl.org/id/ENSGALT00010027706.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015881.1", "url": "https://www.ensembl.org/id/ENSGALP00010015881.1" } ] } }, { "isoform_ac": "A0A8V0YBN7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIL0/entry#A0A8V0YBN7-1", "sequence": { "sequence": "MELGRVLRVPAKLHLLNQETQVNQMIKSMDLLLQRNVAWIASSFCLLASYFWHALWAVLSCRRKRKIPAPGNTQVVKEKLHLSETGTNSTQEEEPPDSAEGVIQNSQSCCHEEEVDKLNKENAERESTVLLQTDSPEFHSEETEEKEEIAFESCYRRSSVQQEDDAVYDACQRITGQEIERESPADEETKEEHQVPGAEEQEERMNEGEGVDSKNEKEDEEPSAPSQNEDEAGQSHDQEAPEGMCKGCGKDDTSPPAPFDHRIVSAKRVGISSYYNVNRNEILGGGRFGQVHKCEEKATGLKLAAKIIKARGDKEKNEVKNEISVMNQLNHVNLIQLYDAFESKNDIVLVMEYVEGGELFDRIIDENCNLTEMDTISFIKQICEGIQYMHQMYILHLDLKPENILCVNRSANQIKIIDFGLARRYKPREKLRVNFGTPEFLAPEVVNYEFVSFPTDMWSVGVIAYMLLSGLSPFLGEDDNETLNNILACSWDFEDEEFQGVSEQAKDFISKLLIKEKCWRISATAALKHPWLSDHKLHCRLQKKVKGDSESQAPSDP", "length": 557, "header": "tr|A0A8V0YBN7-1|A0A8V0YBN7_CHICK Computationally mapped isoform of Myosin light chain kinase family member 4 OS=Gallus gallus OX=9031 GN=MYLK4 PE=3 SV=1 CANONICAL=A0A8V0YIL0-1" }, "locus": { "chromosome": "2", "start_pos": 67320937, "end_pos": 67264076, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027710.1", "url": "https://www.ensembl.org/id/ENSGALT00010027710.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015883.1", "url": "https://www.ensembl.org/id/ENSGALP00010015883.1" } ] } }, { "isoform_ac": "A0A8V0YDX1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIL0/entry#A0A8V0YDX1-1", "sequence": { "sequence": "MGGKQKQLISINDNLKHPIQERGEIRSYECSLVFESKVERKTESKLTGHSMKRLKINRLEEINTRYNSNRLEKTSFFQTMKKVERTEGFHEEKFSGSDPGTEDAEVVKEKLHLSETGTNSTQEEEPPDSAEGVIQNSQSCCHEEEVDKLNKENAERESTVLLQTDSPEFHSEETEEKEEIAFESCYRRSSVQQEDDAVYDACQRITGQEIERESPADEETKEEHQVPGAEEQEERMNEGEGVDSKNEKEDEEPSAPSQNEDEAGQSHDQEAPEGMCKGCGKGTGNYSSVIEQTCQFQYSGNNDTSPPAPFDHRIVSAKRVGISSYYNVNRNEILGGGRFGQVHKCEEKATGLKLAAKIIKARGDKEKNEVKNEISVMNQLNHVNLIQLYDAFESKNDIVLVMEYVEGGELFDRIIDENCNLTEMDTISFIKQICEGIQYMHQMYILHLDLKPENILCVNRSANQIKIIDFGLARRYKPREKLRVNFGTPEFLAPEVVNYEFVSFPTDMWSVGVIAYMLLSGLSPFLGEDDNETLNNILACSWDFEDEEFQGVSEQAKDFISKLLIKEKCWRISATAALKHPWLSDHKLHCRLQKKVKGDSESQAPSDP", "length": 608, "header": "tr|A0A8V0YDX1-1|A0A8V0YIL0_CHICK Computationally mapped isoform of Myosin light chain kinase family member 4 OS=Gallus gallus OX=9031 GN=MYLK4 PE=3 SV=1 CANONICAL=A0A8V0YIL0-1" }, "locus": { "chromosome": "2", "start_pos": 67341064, "end_pos": 67264076, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027714.1", "url": "https://www.ensembl.org/id/ENSGALT00010027714.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015884.1", "url": "https://www.ensembl.org/id/ENSGALP00010015884.1" } ] } }, { "isoform_ac": "A0A8V0YIL0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIL0/entry#A0A8V0YIL0-1", "sequence": { "sequence": "MTTSSRQSSSTSMVNNLAKMFDPNALQNQGPDNTMEPLKIRRVVSSDVSTESFNVMDMKFAFLEQKIDKLLMLQDNVLKKLNSVSQEIYCIEKDIEIVKAETSEPGLKMERNKNLRNNQMKRLCLKMKKSLSDINRNAEQQVKRLDGLEQSVSAIQKLVGPLAEKVKALIIHHSSGKHHILKRKLRKAGDYTKAAGRGFGMQIFSETTADALLKTRSEKVVKEKLHLSETGTNSTQEEEPPDSAEGVIQNSQSCCHEEEVDKLNKENAERESTVLLQTDSPEFHSEETEEKEEIAFESCYRRSSVQQEDDAVYDACQRITGQEIERESPADEETKEEHQVPGAEEQEERMNEGEGVDSKNEKEDEEPSAPSQNEDEAGQSHDQEAPEGMCKGCGKDDTSPPAPFDHRIVSAKRVGISSYYNVNRNEILGGGRFGQVHKCEEKATGLKLAAKIIKARGDKEKNEVKNEISVMNQLNHVNLIQLYDAFESKNDIVLVMEYVEGGELFDRIIDENCNLTEMDTISFIKQICEGIQYMHQMYILHLDLKPENILCVNRSANQIKIIDFGLARRYKPREKLRVNFGTPEFLAPEVVNYEFVSFPTDMWSVGVIAYMLLSGLSPFLGEDDNETLNNILACSWDFEDEEFQGVSEQAKDFISKLLIKEKCWRISATAALKHPWLSDHKLHCRLQKKVKGDSESQAPSDP", "length": 702, "header": "tr|A0A8V0YIL0-1|A0A8V0YIL0_CHICK Isoform 1 of Myosin light chain kinase family member 4 OS=Gallus gallus OX=9031 GN=MYLK4 PE=3 SV=1 CANONICAL=A0A8V0YIL0-1" }, "locus": { "chromosome": "2", "start_pos": 67289976, "end_pos": 67264076, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027709.1", "url": "https://www.ensembl.org/id/ENSGALT00010027709.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015882.1", "url": "https://www.ensembl.org/id/ENSGALP00010015882.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:420893", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420893", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIL0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIL0" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIL0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIL0" } ], "pmid": "" }, { "name": "myosin light chain kinase activity", "id": "GO:0004687", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004687", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIL0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIL0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIL0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIL0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIL0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIL0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 233, "end_pos": 235, "annotation": "n_glycosylation_sequon" }, { "start_pos": 514, "end_pos": 516, "annotation": "n_glycosylation_sequon" }, { "start_pos": 553, "end_pos": 555, "annotation": "n_glycosylation_sequon" }, { "start_pos": 625, "end_pos": 627, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YIL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIL0" }, { "id": "PS50011", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50011" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Protein kinase", "eco_id": "ECO_0000259", "start_pos": 422, "end_pos": 677, "start_aa": "Val", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 233, "end_pos": 235 }, { "start_pos": 514, "end_pos": 516 }, { "start_pos": 553, "end_pos": 555 }, { "start_pos": 625, "end_pos": 627 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YKE3-1", "uniprot_ac": "A0A8V0YKE3", "uniprot_id": "A0A8V0YKE3_CHICK", "mass": { "chemical_mass": 93250.0, "monoisotopic_mass": 93250.0 }, "refseq": { "ac": "XP_015132819", "name": "FYN-binding protein 1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015132819" }, "gene_names": [ { "name": "FYB1", "type": "recommended", "evidence": [ { "id": "A0A8V0YKE3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKE3" } ] }, { "name": "FYB1", "type": "synonym", "evidence": [ { "id": "XP_015132819", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015132819" } ] }, { "name": "FYB", "type": "synonym", "evidence": [ { "id": "XP_015132819", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015132819" } ] } ], "protein_names": [ { "name": "FYN-binding protein 1", "type": "recommended", "evidence": [ { "id": "A0A8V0YKE3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKE3/entry#names_and_taxonomy" } ] }, { "name": "Adhesion and degranulation promoting adaptor protein", "type": "synonym", "evidence": [ { "id": "A0A8V0YKE3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKE3/entry#names_and_taxonomy" } ] }, { "name": "FYB-120/130", "type": "synonym", "evidence": [ { "id": "A0A8V0YKE3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKE3/entry#names_and_taxonomy" } ] }, { "name": "FYN-T-binding protein", "type": "synonym", "evidence": [ { "id": "A0A8V0YKE3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKE3/entry#names_and_taxonomy" } ] }, { "name": "FYN-binding protein 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015132819", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015132819" } ] }, { "name": "SLAP-130", "type": "synonym", "evidence": [ { "id": "A0A8V0YKE3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKE3/entry#names_and_taxonomy" } ] }, { "name": "SLP-76-associated phosphoprotein", "type": "synonym", "evidence": [ { "id": "A0A8V0YKE3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKE3/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052572.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015132819", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015132819" } ] }, { "annotation": "Acts as an adapter protein of the FYN and LCP2 signaling cascades in T-cells. May play a role in linking T-cell signaling to remodeling of the actin cytoskeleton. Modulates the expression of IL2. Involved in platelet activation. Prevents the degradation of SKAP1 and SKAP2. May be involved in high affinity immunoglobulin epsilon receptor signaling in mast cells.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKE3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKE3#function" }, { "database": "UniProtKB", "id": "ARBA00059917", "url": "https://www.uniprot.org/uniprotkb/ARBA00059917#function" }, { "database": "UniProtKB", "id": "A0A8V0YKE9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKE9#function" }, { "database": "UniProtKB", "id": "A0A8V0YMA0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMA0#function" }, { "database": "UniProtKB", "id": "E1C908", "url": "https://www.uniprot.org/uniprotkb/E1C908#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKE3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKE3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "FYB1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKE3", "locus": { "chromosome": "Z", "start_pos": 12821323, "end_pos": 12884129, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013396", "url": "https://www.ensembl.org/id/ENSGALG00010013396" } ] } } ], "crossref": [ { "id": "A0A8V0YKE3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YKE3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000003792", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000003792", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd11867", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11867", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "427448", "url": "https://www.ncbi.nlm.nih.gov/gene/427448", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029294", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029294", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035540", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035540", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036028", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036028", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043443", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043443", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "KSSTWSW", "url": "https://omabrowser.org/oma/group/KSSTWSW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YDZ2", "url": "https://www.orthodb.org/?gene=A0A8V0YDZ2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YKE3", "url": "https://www.orthodb.org/?gene=A0A8V0YKE3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YKE9", "url": "https://www.orthodb.org/?gene=A0A8V0YKE9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YMA0", "url": "https://www.orthodb.org/?gene=A0A8V0YMA0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1C908", "url": "https://www.orthodb.org/?gene=E1C908", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16830", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16830", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16830:SF13", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16830:SF13", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF14603", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14603", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-202433", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-202433", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-391160", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-391160", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_015132819", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015132819", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YDZ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDZ2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YDZ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDZ2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YKE3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKE3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YKE3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKE3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YKE9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKE9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YKE9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKE9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YMA0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMA0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YMA0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMA0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C908", "url": "https://www.uniprot.org/uniprotkb/E1C908", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C908-1", "url": "https://www.uniprot.org/uniprotkb/E1C908-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDGKADVKSLMAKFNGGNSPSEDVSGNIRLSKVTGQPTHSGLQTRKAVFEKFASQGNAASPSGPSVSQKPAHPKPPLAVKPSTEDKTEKDPKPPYLKPVGQRFGVQLQATNRESDGKAGYTKTLTKSSDLAKEEPKSLYPKLAGNKLHNSAPQEKEKRPLGTKPNFNSEAQESEEKTSFSKVAGAKEKFMSATQENDPKPSSSKPALAQKPSLNHAAPHNEDTSSKNVFPHKGLAGPRPNMHSFKATKETDENSNCAAETAGSHFSNMALKPTGHWSSASQGTPRNAEEKTEEKGVSATRNIFLNKIIQEESGSSPPKFHKTSTAFAAGRSLGGSEEKDDRDRSSGAPKRKSLPPLFKLGQPPQKPSRPPSVDLERFQKSIPRDSPKNEGFKQMAPSPAAASAPAPPPPPSSHPSLHAPAAPSLPPRNVKPSSETTNPDTEENYDDVEFLLQGRMGPGNKDGDQGSDGEMYEDINDIRTSREKEKKSEKEEKKRMDQEKKEQKEKEKKEQEIRKKFKLTGPIQVLHQARACVDSKGGKNELTVKQGDQIEIIRLTDNPEGKWLGRIKGCYGYIKTTVVEIDYDSLKTKQQAVVKQPEIDQEVYDDVGEQDSISSQSGGRNGAGNMFPPPPSDQEIYDGVDDTDSVPRSVSQDEDKNDIWSWGILKKLKVKDDKKKSVREKTTKVNGAEDNGDLFRSPSTKQFGKDCGDSDVYDDVDSSDFPPPPPEFNLPKSVSLGKGKSDEKYPQKLKMMEREEKEFRKKFKFEGEIKVLYSTTTVQDLSQRKWGSKDLQIKPGETLEVIQSTDDTKVLCRNEEGKYGYVLRSNLVENDGEIYDDIGEDCIYDND", "length": 846, "header": "tr|A0A8V0YKE3-1|A0A8V0YKE3_CHICK Isoform 1 of FYN-binding protein 1 OS=Gallus gallus OX=9031 GN=FYB1 PE=1 SV=1 CANONICAL=A0A8V0YKE3-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YDZ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKE3/entry#A0A8V0YDZ2-1", "sequence": { "sequence": "MAKFNGGNSPSEDVSGNIRLSKVTGQPTHSGLQTRKAVFEKFASQGNAASPSGPSVSQKPAHPKPPLAVKPSTEDKTEKDPKPPYLKPVGQRFGVQLQATNRESDGKAGYTKTLTKSSDLAKEEPKSLYPKLAGNKLHNSAPQEKEKRPLGTKPNFNSEAQESEEKTSFSKVAGAKEKFMSATQENDPKPSSSKPALAQKPSLNHAAPHNEDTSSKNVFPHKGLAGPRPNMHSFKATKETDENSNCAAETAGSHFSNMALKPTGHWSSASQGTPRNAEEKTEEKGVSATRNIFLNKIIQEESGSSPPKFHKTSTAFAAGRSLGGSEEKDDRDRSSGAPKRKSLPPLFKLGQPPQKPSRPPSVDLERFQKSIPRDSPKNEGFKQMAPSPAAASAPAPPPPPSSHPSLHAPAAPSLPPRNVKPSSETTNPDTEENYDDVEFLLQGRMETSIEICILVNSRTSREKEKKSEKEEKKRMDQEKKEQKEKEKKEQEIRKKFKLTGPIQVLHQARACVDSKGGKNELTVKQGDQIEIIRLTDNPEGKWLGRIKGCYGYIKTTVVEIDYDSLKTKQQAVVKQPEIDQEVYDDVGEQDSISSQSGGRNGAGNMFPPPPSDQEIYDGVDDTDSVPRSVSQDEDKNDIWSWGILKKLKVKDDKKKSVREKTTKVNGAEDNGDLFDVYDDVDSSDFPPPPPEFNLPKSVSLGKGKSDEKYPQKLKMMEREEKEFRKKFKFEGEIKVLYSTTTVQDLSQRKWGSKDLQIKPGETLEVIQSTDDTKVLCRNEEGKCKFQ", "length": 786, "header": "tr|A0A8V0YDZ2-1|A0A8V0YKE3_CHICK Computationally mapped isoform of FYN-binding protein 1 OS=Gallus gallus OX=9031 GN=FYB1 PE=1 SV=1 CANONICAL=A0A8V0YKE3-1" }, "locus": { "chromosome": "Z", "start_pos": 12863547, "end_pos": 12828261, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032247.1", "url": "https://www.ensembl.org/id/ENSGALT00010032247.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019037.1", "url": "https://www.ensembl.org/id/ENSGALP00010019037.1" } ] } }, { "isoform_ac": "A0A8V0YKE3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKE3/entry#A0A8V0YKE3-1", "sequence": { "sequence": "MDGKADVKSLMAKFNGGNSPSEDVSGNIRLSKVTGQPTHSGLQTRKAVFEKFASQGNAASPSGPSVSQKPAHPKPPLAVKPSTEDKTEKDPKPPYLKPVGQRFGVQLQATNRESDGKAGYTKTLTKSSDLAKEEPKSLYPKLAGNKLHNSAPQEKEKRPLGTKPNFNSEAQESEEKTSFSKVAGAKEKFMSATQENDPKPSSSKPALAQKPSLNHAAPHNEDTSSKNVFPHKGLAGPRPNMHSFKATKETDENSNCAAETAGSHFSNMALKPTGHWSSASQGTPRNAEEKTEEKGVSATRNIFLNKIIQEESGSSPPKFHKTSTAFAAGRSLGGSEEKDDRDRSSGAPKRKSLPPLFKLGQPPQKPSRPPSVDLERFQKSIPRDSPKNEGFKQMAPSPAAASAPAPPPPPSSHPSLHAPAAPSLPPRNVKPSSETTNPDTEENYDDVEFLLQGRMGPGNKDGDQGSDGEMYEDINDIRTSREKEKKSEKEEKKRMDQEKKEQKEKEKKEQEIRKKFKLTGPIQVLHQARACVDSKGGKNELTVKQGDQIEIIRLTDNPEGKWLGRIKGCYGYIKTTVVEIDYDSLKTKQQAVVKQPEIDQEVYDDVGEQDSISSQSGGRNGAGNMFPPPPSDQEIYDGVDDTDSVPRSVSQDEDKNDIWSWGILKKLKVKDDKKKSVREKTTKVNGAEDNGDLFRSPSTKQFGKDCGDSDVYDDVDSSDFPPPPPEFNLPKSVSLGKGKSDEKYPQKLKMMEREEKEFRKKFKFEGEIKVLYSTTTVQDLSQRKWGSKDLQIKPGETLEVIQSTDDTKVLCRNEEGKYGYVLRSNLVENDGEIYDDIGEDCIYDND", "length": 846, "header": "tr|A0A8V0YKE3-1|A0A8V0YKE3_CHICK Isoform 1 of FYN-binding protein 1 OS=Gallus gallus OX=9031 GN=FYB1 PE=1 SV=1 CANONICAL=A0A8V0YKE3-1" }, "locus": { "chromosome": "Z", "start_pos": 12883838, "end_pos": 12823680, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032266.1", "url": "https://www.ensembl.org/id/ENSGALT00010032266.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019055.1", "url": "https://www.ensembl.org/id/ENSGALP00010019055.1" } ] } }, { "isoform_ac": "A0A8V0YKE9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKE3/entry#A0A8V0YKE9-1", "sequence": { "sequence": "MDGKADVKSLMAKFNGGNSPSEDVSGNIRLSKVTGQPTHSGLQTRKAVFEKFASQGNAASPSGPSVSQKPAHPKPPLAVKPSTEDKTEKDPKPPYLKPVGQRFGVQLQATNRESDGKAGYTKTLTKSSDLAKEEPKSLYPKLAGNKLHNSAPQEKEKRPLGTKPNFNSEAQESEEKTSFSKVAGAKEKFMSATQENDPKPSSSKPALAQKPSLNHAAPHNEDTSSKNVFPHKGLAGPRPNMHSFKATKETDENSNCAAETAGSHFSNMALKPTGHWSSASQGTPRNAEEKTEEKGVSATRNIFLNKIIQEESGSSPPKFHKTSTAFAAGRSLGGSEEKDDRDRSSGAPKRKSLPPLFKLGQPPQKPSRPPSVDLERFQKSIPRDSPKNEGFKQMAPSPAAASAPAPPPPPSSHPSLHAPAAPSLPPRNVKPSSETTNPDTEENYDDVEFLLQGRMGPGNKDGDQGSDGEMYEDINDIRTSREKEKKSEKEEKKRMDQEKKEQKEKEKKEQEIRKKFKLTGPIQVLHQARACVDSKGGKNELTVKQGDQIEIIRLTDNPEGKWLGRIKGCYGYIKTTVVEIDYDSLKTKQQAVVKQPEIDQEVYDDVGEQDSISSQSGGRNGAGNMFPPPPSDQEIYDGVDDTDSVPRSPSTKQFGKDCGDSDVYDDVDSSDFPPPPPEFNLPKSVSLGKGKSDEKYPQKLKMMEREEKEFRKKFKFEGEIKVLYSTTTVQDLSQRKWGSKDLQIKPGETLEVIQSTDDTKVLCRNEEGKYGYVLRSNLVENDGEIYDDIGEDCIYDND", "length": 798, "header": "tr|A0A8V0YKE9-1|A0A8V0YKE9_CHICK Computationally mapped isoform of FYN-binding protein 1 OS=Gallus gallus OX=9031 GN=FYB1 PE=1 SV=1 CANONICAL=A0A8V0YKE3-1" }, "locus": { "chromosome": "Z", "start_pos": 12883838, "end_pos": 12823680, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032270.1", "url": "https://www.ensembl.org/id/ENSGALT00010032270.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019060.1", "url": "https://www.ensembl.org/id/ENSGALP00010019060.1" } ] } }, { "isoform_ac": "A0A8V0YMA0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKE3/entry#A0A8V0YMA0-1", "sequence": { "sequence": "MAKFNGGNSPSEDVSGNIRLSKVTGQPTHSGLQTRKAVFEKFASQGNAASPSGPSVSQKPAHPKPPLAVKPSTEDKTEKDPKPPYLKPVGQRFGVQLQATNRESDGKAGYTKTLTKSSDLAKEEPKSLYPKLAGNKLHNSAPQEKEKRPLGTKPNFNSEAQESEEKTSFSKVAGAKEKFMSATQENDPKPSSSKPALAQKPSLNHAAPHNEDTSSKNVFPHKGLAGPRPNMHSFKATKETDENSNCAAETAGSHFSNMALKPTGHWSSASQGTPRNAEEKTEEKGVSATRNIFLNKIIQEESGSSPPKFHKTSTAFAAGRSLGGSEEKDDRDRSSGAPKRKSLPPLFKLGQPPQKPSRPPSVDLERFQKSIPRDSPKNEGFKQMAPSPAAASAPAPPPPPSSHPSLHAPAAPSLPPRNVKPSSETTNPDTEENYDDVEFLLQGRMGPGNKDGDQGSDGEMYEDINDIRTSREKEKKSEKEEKKRMDQEKKEQKEKEKKEQEIRKKFKLTGPIQVLHQARACVDSKGGKNELTVKQGDQIEIIRLTDNPEGKWLGRIKGCYGYIKTTVVEIDYDSLKTKQQAVVKQPEIDQEVYDDVGEQDSISSQSGGRNGAGNMFPPPPSDQEIYDGVDDTDSVPRSVSQDEDKNDIWSWGILKKLKVKDDKKKSVREKTTKVNGAEDNGDLLSPSTKQFGKDCGDSDVYDDVDSSDFPPPPPEFNLPKSVSLGKGKSDEKYPQKLKMMEREEKEFRKKFKFEGEIKVLYSTTTVQDLSQRKWGSKDLQIKPGETLEVIQSTDDTKVLCRNEEGKYGYVLRSNLVENDGEIYDDIGEDCIYDND", "length": 835, "header": "tr|A0A8V0YMA0-1|A0A8V0YMA0_CHICK Computationally mapped isoform of FYN-binding protein 1 OS=Gallus gallus OX=9031 GN=FYB1 PE=1 SV=1 CANONICAL=A0A8V0YKE3-1" }, "locus": { "chromosome": "Z", "start_pos": 12863547, "end_pos": 12823680, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032260.1", "url": "https://www.ensembl.org/id/ENSGALT00010032260.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019050.1", "url": "https://www.ensembl.org/id/ENSGALP00010019050.1" } ] } }, { "isoform_ac": "E1C908-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKE3/entry#E1C908-1", "sequence": { "sequence": "MAKFNGGNSPSEDVSGNIRLSKVTGQPTHSGLQTRKAVFEKFASQGNAASPSGPSVSQKPAHPKPPLAVKPSTEDKTEKDPKPPYLKPVGQRFGVQLQATNRESDGKAGYTKTLTKSSDLAKEEPKSLYPKLAGNKLHNSAPQEKEKRPLGTKPNFNSEAQESEEKTSFSKVAGAKEKFMSATQENDPKPSSSKPALAQKPSLNHAAPHNEDTSSKNVFPHKGLAGPRPNMHSFKATKETDENSNCAAETAGSHFSNMALKPTGHWSSASQGTPRNAEEKTEEKGVSATRNIFLNKIIQEESGSSPPKFHKTSTAFAAGRSLGGSEEKDDRDRSSGAPKRKSLPPLFKLGQPPQKPSRPPSVDLERFQKSIPRDSPKNEGFKQMAPSPAAASAPAPPPPPSSHPSLHAPAAPSLPPRNVKPSSETTNPDTEENYDDVEFLLQGRMGPGNKDGDQGSDGEMYEDINDIRTSREKEKKSEKEEKKRMDQEKKEQKEKEKKEQEIRKKFKLTGPIQVLHQARACVDSKGGKNELTVKQGDQIEIIRLTDNPEGKWLGRIKGCYGYIKTTVVEIDYDSLKTKQQAVVKQPEIDQEVYDDVGEQDSISSQSGGRNGAGNMFPPPPSDQEIYDGVDDTDSVPRSVSQDEDKNDIWSWGILKKLKVKDDKKKSVREKTTKVNGAEDNGDLFRSPSTKQFGKDCGDSDVYDDVDSSDFPPPPPEFNLPKSVSLGKGKSDEKYPQKLKMMEREEKEFRKKFKFEGEIKVLYSTTTVQDLSQRKWGSKDLQIKPGETLEVIQSTDDTKVLCRNEEGKYGYVLRSNLVENDGEIYDDIGEDCIYDND", "length": 836, "header": "tr|E1C908-1|E1C908_CHICK Computationally mapped isoform of FYN-binding protein 1 OS=Gallus gallus OX=9031 GN=FYB1 PE=1 SV=4 CANONICAL=A0A8V0YKE3-1" }, "locus": { "chromosome": "Z", "start_pos": 12863547, "end_pos": 12823680, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032250.1", "url": "https://www.ensembl.org/id/ENSGALT00010032250.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019040.1", "url": "https://www.ensembl.org/id/ENSGALP00010019040.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-202433", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-202433", "resource": "Reactome", "description": "Generation of second messenger molecules" }, { "id": "R-GGA-391160", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-391160", "resource": "Reactome", "description": "Signal regulatory protein family interactions" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZIE4-1", "protein_name": "FYN-binding protein 1", "gene_name": "Fyb1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDGKTDVKSLMAKFNTGSNPTEEVSTSSRPFKVAGQNSPSGIQSKKNLFDNQGNASPPAGPSNMSKFGTTKPPLAAKPTYEEKSEKEPKPPFLKPTGVSPRFGTQPNSVSRDPEVKVGFLKPVSPKPTSLTKEDSKPVILRPPGNKLHNLNQESDLKTLGPKPGSTPPVPENDLKPGFSKIAGAKSKFMPAPQDADSKPRFPRHTYGQKPSLSTEDAQEEESIPKNTPVQKGSPVQLGAKSRGSPFKPAKEDPEDKDHGTPSSPFAGVVLKPAASRGSPGLSKNSEEKKEERKTDIPKNIFLNKLNQEEPARFPKAPSKLTAGTPWGQSQEKEGDKDSATPKQKPLPPLSVLGPPPSKPSRPPNVDLTRFRKADSANSSNKSQTPYSTTSLPPPPPTQPASQPPLPASHPAHLPAPSLPPRNIKPPLDLKHPINEENQDGVMHSDGTGNLEEEQESDGEMYEDIESSKERDKKREKEEKKRLELERKEQKEREKKEQELRKKFKLTGPIQVIHHAKACCDVKGGKNELSFKQGEDIEIIRITDNPEGKWLGRTARGSYGYIKTTAVKIDYDSLKRKKNTINAVPPRPVEEDQDVYDDVAEQDAPNSHSQSGSGGMFPPPPADDDIYDGIEEEDADDGSVPQVDEKTNAWSWGILKMLKGKDERKKSIREKPKVSESDSNEGSSFPSPHKQLDVGEEVYDDVDASDFPPPPAEMSQGMSVGKTKAEEKDPKKLKKQEKEEKDLRKKFKYDGEIRVLYSTKVASSLTSKKWGTRDLQIKPGESLEVIQSTDDTKVLCRNEEGKYGYVLRSYLVDNDGEIYDDIADGCIYDND", "length": 830 }, "evidence": [ { "id": "A0A8V0YKE3", "url": "https://omabrowser.org/oma/group/A0A8V0YKE3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O15117-1", "protein_name": "FYN-binding protein 1", "gene_name": "FYB1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAKYNTGGNPTEDVSVNSRPFRVTGPNSSSGIQARKNLFNNQGNASPPAGPSNVPKFGSPKPPVAVKPSSEEKPDKEPKPPFLKPTGAGQRFGTPASLTTRDPEAKVGFLKPVGPKPINLPKEDSKPTFPWPPGNKPSLHSVNQDHDLKPLGPKSGPTPPTSENEQKQAFPKLTGVKGKFMSASQDLEPKPLFPKPAFGQKPPLSTENSHEDESPMKNVSSSKGSPAPLGVRSKSGPLKPAREDSENKDHAGEISSLPFPGVVLKPAASRGGPGLSKNGEEKKEDRKIDAAKNTFQSKINQEELASGTPPARFPKAPSKLTVGGPWGQSQEKEKGDKNSATPKQKPLPPLFTLGPPPPKPNRPPNVDLTKFHKTSSGNSTSKGQTSYSTTSLPPPPPSHPASQPPLPASHPSQPPVPSLPPRNIKPPFDLKSPVNEDNQDGVTHSDGAGNLDEEQDSEGETYEDIEASKEREKKREKEEKKRLELEKKEQKEKEKKEQEIKKKFKLTGPIQVIHLAKACCDVKGGKNELSFKQGEQIEIIRITDNPEGKWLGRTARGSYGYIKTTAVEIDYDSLKLKKDSLGAPSRPIEDDQEVYDDVAEQDDISSHSQSGSGGIFPPPPDDDIYDGIEEEDADDGFPAPPKQLDMGDEVYDDVDTSDFPVSSAEMSQGTNVGKAKTEEKDLKKLKKQEKEEKDFRKKFKYDGEIRVLYSTKVTTSITSKKWGTRDLQVKPGESLEVIQTTDDTKVLCRNEEGKYGYVLRSYLADNDGEIYDDIADGCIYDND", "length": 783 }, "evidence": [ { "id": "A0A8V0YKE3", "url": "https://omabrowser.org/oma/group/A0A8V0YKE3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "O35601-1", "protein_name": "FYN-binding protein 1", "gene_name": "Fyb1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAKFNTGSNPTEEAATSSRPFKVAGQSSPSGIQSRKNLFDNQGNASPPAGPSSMPKFGTTKPPLAAKPTYEEKPEKEPKPPFLKPTGGSPRFGTQPNSVSRDPEVKVGFLKPVSPKPTSLTKEDSKPVVLRPPGNKLHNLNQESDLKTPGPKPGPAPPVPENELKPGFSKVAGAKSKFMPAAQDTDSKPRFPRHTFGQKPSLSTEDSQEENTSKNVPVQKGSPVQLGAKSKGAPFKPPKEDPEDKDHGAPSSPFPGVVLKPAASRGSPGLSKNFEEKKEDRKTDLAKNIFLNKLNQEEPARFPKAPSKLTAGTPWGQSQEKEGDKNSATPKQKALPPLSVLGPPPPKPNRPPNVDLTRFRKADSANSATKSQTPYSTTSLPPPPPTHPASQPPLPASHPAHPPVPSLPPRNIKPPLDLKHPINDENQDGVMHSDGTGNLEEEQESEGETYEDIDSSKERDKKREKEEKKRLELERKEQKEREKKEQELKKKFKLTGPIQVIHHAKACCDVKGGKNELSFKQGEDIEIIRITDNPEGKWLGRTARGSYGYIKTTAVEIDYDSLKRKKNSLNAVPPRLVEDDQDVYDDVAEQDAPNSHGQSGSGGMFPPPPTDDEIYDGIEEEDDDDGSVPQVDEKTNAWSWGILKMLKGKDDRKKSIREKPKVSESDNNEGSSLPSQHKQLDVGEEVYDDVDASDFPPPPAEMSQGMSVGRAKTEEKDPKKLKKQEKEEKDLRKKFKYDGEIRVLYSTKVASSLTSKKWGARDLQIKPGESLEVIQSTDDTKVLCRNEEGKYGYVLRSYLVDNDGEIYDDIADGCIYDND", "length": 819 }, "evidence": [ { "id": "A0A8V0YKE3", "url": "https://omabrowser.org/oma/group/A0A8V0YKE3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKE3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKE3" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKE3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKE3" } ], "pmid": "" }, { "name": "protein-containing complex", "id": "GO:0032991", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032991", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKE3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKE3" } ], "pmid": "" }, { "name": "anchoring junction", "id": "GO:0070161", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070161", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKE3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKE3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "integrin-mediated signaling pathway", "id": "GO:0007229", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007229", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKE3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKE3" } ], "pmid": "" }, { "name": "protein localization to plasma membrane", "id": "GO:0072659", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072659", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKE3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKE3" } ], "pmid": "" }, { "name": "T cell receptor signaling pathway", "id": "GO:0050852", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050852", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKE3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKE3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "lipid binding", "id": "GO:0008289", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008289", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKE3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKE3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YKE3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKE3" }, { "id": "PS50002", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50002" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SH3", "eco_id": "ECO_0000259", "start_pos": 523, "end_pos": 583, "start_aa": "Gln", "end_aa": "Asp", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YKZ3-1", "uniprot_ac": "A0A8V0YKZ3", "uniprot_id": "A0A8V0YKZ3_CHICK", "mass": { "chemical_mass": 116874.0, "monoisotopic_mass": 116874.0 }, "refseq": {}, "gene_names": [ { "name": "IPO8", "type": "recommended", "evidence": [ { "id": "A0A8V0YKZ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKZ3" } ] } ], "protein_names": [ { "name": "Importin 8", "type": "synonym", "evidence": [ { "id": "A0A8V0YKZ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKZ3/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKZ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKZ3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "IPO8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKZ3", "locus": { "chromosome": "1", "start_pos": 59709555, "end_pos": 59666953, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012085", "url": "https://www.ensembl.org/id/ENSGALG00010012085" } ] } } ], "crossref": [ { "id": "A0A8V0YKZ3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YKZ3", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR001494", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001494", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013713", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013713", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR058669", "url": "https://www.ebi.ac.uk/interpro/entry/IPR058669", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YDZ9", "url": "https://www.orthodb.org/?gene=A0A8V0YDZ9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YE04", "url": "https://www.orthodb.org/?gene=A0A8V0YE04", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YKZ3", "url": "https://www.orthodb.org/?gene=A0A8V0YKZ3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10997", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10997", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10997:SF26", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10997:SF26", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03810", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03810", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08506", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08506", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25758", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25758", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-5578749", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5578749", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YDZ9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDZ9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YDZ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDZ9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YE04", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE04", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YE04-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE04-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YKZ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKZ3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YKZ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKZ3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDPNRIIQALKGTIDPKLRIAAENELNQSYKIINFAPSLLQIIVSDQVEFPVRQAAAIYLKNMVTQYWPDREPPPGEAVFPFNIHENDRQQIRDNIVEGIIRSPDLVRAQLTMCLRAIIKHDFPGHWTAVVDKIGYYLQSQNSGSWLGSLLCLYQLVKTYEYKKAEERDPLIAAMQIFLPRIQQQMIQLLPDNSHYSVLLQKQILKIFYALVQYALPLQLVNNQTMTQWMEIFRTIIDRNVPPETLQIDEDDRPELVWWKCKKWALHIVARLFERYGSPGNVTKEYFEFSEFFLKTYAVGIQQVLLRILDQYRQKDYVAPRVLQQTLNYLNQGVIHSVTWKQMKPHIQSITEEVIFSLMCYKDEDEELWQEDPYEYIRMKFDVFEDYASTTTAAQNLLYTAAKKRKEVLPKMMAYCYQILTEPNIDPRKKDGALHVIGSLADILLKKSVFKDQMELMLQNHVFPLFMSNLGYLRARSCWVLHSFSALNFHNELNLRNAVELAKKSLIDDKEMPVKVEAAIALQMLISHQEQAKEYVKPYVRPVMQELLHIVRETENDDLTNVIQKMICEYSQEVATIAVDMTQHLAEIFGKVLQSEEYEEVEDKTVMAMGILHTIDTILTVVEDHKEITQQLESICLQIIGLVLQKHVIEFYEEILSLAYSLTCQMISPQMWQLLGVLYEVFQQDCFEYFADMMPLLHNYVTIDTDTLLSNPKHLEIIYAMCKKVLTGDAGEDAECHAAKLLEVIVLQCKGRGIDQCIPLFVEAVLERLTRGVKTSELRTMCLQVAIAALYYNPDLLLHTLENIRFPHNPEPITAQFINQWMNDTDCFLGLHDRKMCIIGLSILMELQNRPPAVDAVAAQIVPSILLLFLGLKQVCASRELTEHEDHAKDEKHVAEDNEEIPSDEEETNEVSQAMQENHGGGGDGGGEEEDDDDDDDDWDEDALEETALEGFSTPLDLENGVDEYQFFTQALLAVQSRDAAWYHLLTAPLSEDQKKQLQEIYTLAEHRRNAAD", "length": 1013, "header": "tr|A0A8V0YKZ3-1|A0A8V0YKZ3_CHICK Isoform 1 of Importin 8 OS=Gallus gallus OX=9031 GN=IPO8 PE=3 SV=1 CANONICAL=A0A8V0YKZ3-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YDZ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKZ3/entry#A0A8V0YDZ9-1", "sequence": { "sequence": "MSFPKLHLLSLTSYFRSAIYLKNMVTQYWPDREPPPGEAVFPFNIHENDRQQIRDNIVEGIIRSPDLVRAQLTMCLRAIIKHDFPGHWTAVVDKIGYYLQSQNSGSWLGSLLCLYQLVKTYEYKKAEERDPLIAAMQIFLPRIQQQMIQLLPDNSHYSVLLQKQILKIFYALVQYALPLQLVNNQTMTQWMEIFRTIIDRNVPPETLQIDEDDRPELVWWKCKKWALHIVARLFERYGSPGNVTKEYFEFSEFFLKTYAVGIQQVLLRILDQYRQKDYVAPRVLQQTLNYLNQGVIHSVTWKQMKPHIQSITEEVIFSLMCYKDEDEELWQEDPYEYIRMKFDVFEDYASTTTAAQNLLYTAAKKRKEVLPKMMAYCYQILTEPNIDPRKKDGALHVIGSLADILLKKSVFKDQMELMLQNHVFPLFMSNLGYLRARSCWVLHSFSALNFHNELNLRNAVELAKKSLIDDKEMPVKVEAAIALQMLISHQEQAKEYVKPYVRPVMQELLHIVRETENDDLTNVIQKMICEYSQEVATIAVDMTQHLAEIFGKVLQSEEYEEVEDKTVMAMGILHTIDTILTVVEDHKEITQQLESICLQIIGLVLQKHVIEFYEEILSLAYSLTCQMISPQMWQLLGVLYEVFQQDCFEYFADMMPLLHNYVTIDTDTLLSNPKHLEIIYAMCKKVLTGDAGEDAECHAAKLLEVIVLQCKGRGIDQCIPLFVEAVLERLTRGVKTSELRTMCLQVAIAALYYNPDLLLHTLENIRFPHNPEPITAQFINQWMNDTDCFLGLHDRKMCIIGLSILMELQNRPPAVDAVAAQIVPSILLLFLGLKQVCASRELTEHEDHAKDEKHVAEDNEEIPSDEEETNEVSQAMQENHGGGGDGGGEEEDDDDDDDDWDEDALEETALEGFSTPLDLENGVDEYQFFTQALLAVQSRDAAWYHLLTAPLSEDQKKQLQEIYTLAEHRRNAAETKTIEQQSGYTFDNKGLIIAFNFAGSTPGGN", "length": 1005, "header": "tr|A0A8V0YDZ9-1|A0A8V0YKZ3_CHICK Computationally mapped isoform of Importin 8 OS=Gallus gallus OX=9031 GN=IPO8 PE=3 SV=1 CANONICAL=A0A8V0YKZ3-1" }, "locus": { "chromosome": "1", "start_pos": 59708288, "end_pos": 59675272, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028960.1", "url": "https://www.ensembl.org/id/ENSGALT00010028960.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016719.1", "url": "https://www.ensembl.org/id/ENSGALP00010016719.1" } ] } }, { "isoform_ac": "A0A8V0YE04-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKZ3/entry#A0A8V0YE04-1", "sequence": { "sequence": "MVFAHKNEGRLCSAAIYLKNMVTQYWPDREPPPGEAVFPFNIHENDRQQIRDNIVEGIIRSPDLVRAQLTMCLRAIIKHDFPGHWTAVVDKIGYYLQSQNSGSWLGSLLCLYQLVKTYEYKKAEERDPLIAAMQIFLPRIQQQMIQLLPDNSHYSVLLQKQILKIFYALVQYALPLQLVNNQTMTQWMEIFRTIIDRNVPPETLQIDEDDRPELVWWKCKKWALHIVARLFERYGSPGNVTKEYFEFSEFFLKTYAVGIQQVLLRILDQYRQKDYVAPRVLQQTLNYLNQGVIHSVTWKQMKPHIQSITEEVIFSLMCYKDEDEELWQEDPYEYIRMKFDVFEDYASTTTAAQNLLYTAAKKRKEVLPKMMAYCYQILTEPNIDPRKKDGALHVIGSLADILLKKSVFKDQMELMLQNHVFPLFMSNLGYLRARSCWVLHSFSALNFHNELNLRNAVELAKKSLIDDKEMPVKVEAAIALQMLISHQEQAKEYVKPYVRPVMQELLHIVRETENDDLTNVIQKMICEYSQEVATIAVDMTQHLAEIFGKVLQSEEYEEVEDKTVMAMGILHTIDTILTVVEDHKEITQQLESICLQIIGLVLQKHVIEFYEEILSLAYSLTCQMISPQMWQLLGVLYEVFQQDCFEYFADMMPLLHNYVTIDTDTLLSNPKHLEIIYAMCKKVLTGDAGEDAECHAAKLLEVIVLQCKGRGIDQCIPLFVEAVLERLTRGVKTSELRTMCLQVAIAALYYNPDLLLHTLENIRFPHNPEPITAQFINQWMNDTDCFLGLHDRKMCIIGLSILMELQNRPPAVDAVAAQIVPSILLLFLGLKQVCASRELTEHEDHAKDEKHVAEDNEEIPSDEEETNEVSQAMQENHGGGGDGGGEEEDDDDDDDDWDEDALEETALEGFSTPLDLENGVDEYQFFTQALLAVQSRDAAWYHLLTAPLSEDQKKQLQEIYTLAEHRRNAAETKTIEQQSGYTFDNKGLIIAFNFAGSTPGGN", "length": 1002, "header": "tr|A0A8V0YE04-1|A0A8V0YKZ3_CHICK Computationally mapped isoform of Importin 8 OS=Gallus gallus OX=9031 GN=IPO8 PE=3 SV=1 CANONICAL=A0A8V0YKZ3-1" }, "locus": { "chromosome": "1", "start_pos": 59708288, "end_pos": 59674062, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028965.1", "url": "https://www.ensembl.org/id/ENSGALT00010028965.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016724.1", "url": "https://www.ensembl.org/id/ENSGALP00010016724.1" } ] } }, { "isoform_ac": "A0A8V0YKZ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKZ3/entry#A0A8V0YKZ3-1", "sequence": { "sequence": "MDPNRIIQALKGTIDPKLRIAAENELNQSYKIINFAPSLLQIIVSDQVEFPVRQAAAIYLKNMVTQYWPDREPPPGEAVFPFNIHENDRQQIRDNIVEGIIRSPDLVRAQLTMCLRAIIKHDFPGHWTAVVDKIGYYLQSQNSGSWLGSLLCLYQLVKTYEYKKAEERDPLIAAMQIFLPRIQQQMIQLLPDNSHYSVLLQKQILKIFYALVQYALPLQLVNNQTMTQWMEIFRTIIDRNVPPETLQIDEDDRPELVWWKCKKWALHIVARLFERYGSPGNVTKEYFEFSEFFLKTYAVGIQQVLLRILDQYRQKDYVAPRVLQQTLNYLNQGVIHSVTWKQMKPHIQSITEEVIFSLMCYKDEDEELWQEDPYEYIRMKFDVFEDYASTTTAAQNLLYTAAKKRKEVLPKMMAYCYQILTEPNIDPRKKDGALHVIGSLADILLKKSVFKDQMELMLQNHVFPLFMSNLGYLRARSCWVLHSFSALNFHNELNLRNAVELAKKSLIDDKEMPVKVEAAIALQMLISHQEQAKEYVKPYVRPVMQELLHIVRETENDDLTNVIQKMICEYSQEVATIAVDMTQHLAEIFGKVLQSEEYEEVEDKTVMAMGILHTIDTILTVVEDHKEITQQLESICLQIIGLVLQKHVIEFYEEILSLAYSLTCQMISPQMWQLLGVLYEVFQQDCFEYFADMMPLLHNYVTIDTDTLLSNPKHLEIIYAMCKKVLTGDAGEDAECHAAKLLEVIVLQCKGRGIDQCIPLFVEAVLERLTRGVKTSELRTMCLQVAIAALYYNPDLLLHTLENIRFPHNPEPITAQFINQWMNDTDCFLGLHDRKMCIIGLSILMELQNRPPAVDAVAAQIVPSILLLFLGLKQVCASRELTEHEDHAKDEKHVAEDNEEIPSDEEETNEVSQAMQENHGGGGDGGGEEEDDDDDDDDWDEDALEETALEGFSTPLDLENGVDEYQFFTQALLAVQSRDAAWYHLLTAPLSEDQKKQLQEIYTLAEHRRNAAD", "length": 1013, "header": "tr|A0A8V0YKZ3-1|A0A8V0YKZ3_CHICK Isoform 1 of Importin 8 OS=Gallus gallus OX=9031 GN=IPO8 PE=3 SV=1 CANONICAL=A0A8V0YKZ3-1" }, "locus": { "chromosome": "1", "start_pos": 59708197, "end_pos": 59667122, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028974.1", "url": "https://www.ensembl.org/id/ENSGALT00010028974.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016733.1", "url": "https://www.ensembl.org/id/ENSGALP00010016733.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-5578749", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5578749", "resource": "Reactome", "description": "Transcriptional regulation by small RNAs" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKZ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKZ3" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKZ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKZ3" } ], "pmid": "" }, { "name": "nuclear envelope", "id": "GO:0005635", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005635", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKZ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKZ3" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKZ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKZ3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "intracellular protein transport", "id": "GO:0006886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKZ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKZ3" } ], "pmid": "" }, { "name": "protein import into nucleus", "id": "GO:0006606", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006606", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKZ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKZ3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "small GTPase binding", "id": "GO:0031267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031267", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKZ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKZ3" } ], "pmid": "" }, { "name": "nuclear import signal receptor activity", "id": "GO:0061608", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061608", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKZ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKZ3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 223, "end_pos": 225, "annotation": "n_glycosylation_sequon" }, { "start_pos": 27, "end_pos": 29, "annotation": "n_glycosylation_sequon" }, { "start_pos": 281, "end_pos": 283, "annotation": "n_glycosylation_sequon" }, { "start_pos": 823, "end_pos": 825, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YKZ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKZ3" }, { "id": "PS50166", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50166" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Importin N-terminal", "eco_id": "ECO_0000259", "start_pos": 22, "end_pos": 102, "start_aa": "Ala", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 223, "end_pos": 225 }, { "start_pos": 27, "end_pos": 29 }, { "start_pos": 281, "end_pos": 283 }, { "start_pos": 823, "end_pos": 825 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { 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"count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YIR0-1", "uniprot_ac": "A0A8V0YIR0", "uniprot_id": "A0A8V0YIR0_CHICK", "mass": { "chemical_mass": 73271.0, "monoisotopic_mass": 73271.0 }, "refseq": {}, "gene_names": [ { "name": "DELE", "type": "recommended", "evidence": [ { "id": "A0A8V0YIR0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIR0" } ] } ], "protein_names": [ { "name": "DAP3 binding cell death enhancer 1", "type": "synonym", "evidence": [ { "id": "A0A8V0YIR0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIR0/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIR0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIR0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "DELE", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIR0", "locus": {} } ], "crossref": [ { "id": "A0A8V0YIR0", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YIR0", "database": "AlphaFoldDB", "categories": [] }, { "id": "769453", "url": "https://www.ncbi.nlm.nih.gov/gene/769453", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006597", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006597", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011990", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011990", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052748", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052748", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:769453", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:769453", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CQLPHYS", "url": "https://omabrowser.org/oma/group/CQLPHYS/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YE15", "url": "https://www.orthodb.org/?gene=A0A8V0YE15", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YIR0", "url": "https://www.orthodb.org/?gene=A0A8V0YIR0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45011", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45011", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45011:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45011:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF08238", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08238", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-9840373", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9840373", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YE15", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE15", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YE15-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE15-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YIR0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIR0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YIR0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIR0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTRCYLYSCRLWHASCLPHRDAPRQAEGLCPQSPRSAAQPPAPRRFIPLSYRGPTARPSPGAHETTPSPGALRARAFPLLAAAPGPGPPRRSRAVLKGGQGAPAPLYASRRSCRHSPAGTPRRSPVSRPLYGHEEPLCSAVAEQRALSMVPRAACGGCCWAAAASRAACCRPPAPRPPPPPTLPTAAAPRGECGPRPSRRAAACPARPSRREGRRHRLVFCRCCGAPGCQHGGARDGREREGWRQPLPGLVPRYSVLDAVTWGALAALLLQLVRQISWLRSLPDARREPRPPWLPSLPAQHTVVSDASAGLPCAQLGPCFLQKAEVAPENSSSSFPLGPGDSQLWAEEGEFPVPQCSSPRPVPRSTKENPAKREHLEEAAFQLQQIFRVDISIAFNILGIESMRAGHYQIGYTCFKLAADRGYSKAQFNVGLCYEHGRGTEKDLEKAAFYYYRAASSCHPMAQYRYARCLLCHSPENEWHRLQKAVTFLEQAAVAGLTEAQAYLGVFYMRGLQPKEKKGLKYLLLAAKNGDAQSRYHVGVCYEKGLGVQQNLAEAMRHYQQSAAAGNRNAQERLRVIEEEMEDVRRKHPFPFGMRTSSSSPCFWATERVPAGLHTFQPRQPALTLPHSWSADRLHMMTLGSAEWSHALGNRASPLELQGLEPHHCGY", "length": 667, "header": "tr|A0A8V0YIR0-1|A0A8V0YIR0_CHICK Isoform 1 of DAP3 binding cell death enhancer 1 OS=Gallus gallus OX=9031 GN=DELE PE=4 SV=1 CANONICAL=A0A8V0YIR0-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YE15-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIR0/entry#A0A8V0YE15-1", "sequence": { "sequence": "MWRLLLGRSGLARCLLPPARPAAATASDSADSRGSARCCGAPGCQHGGARDGREREGWRQPLPGLVPRYSVLDAVTWGALAALLLQLVRQISWLRSLPDARREPRPPWLPSLPAQHTVVSDASAGLPCAQLGPCFLQKAEVAPENSSSSFPLGPGDSQLWAEEGEFPVPQCSSPRPVPRSTKENPAKREHLEEAAFQLQQIFRVDISIAFNILGIESMRAGHYQIGYTCFKLAADRGYSKAQFNVGLCYEHGRGTEKDLEKAAFYYYRAASSCHPMAQYRYARCLLCHSPENEWHRLQKAVTFLEQAAVAGLTEAQAYLGVFYMRGLQPKEKKGLKYLLLAAKNGDAQSRYHVGVCYEKGLGVQQNLAEAMRHYQQSAAAGNRNAQERLRVIEEEMEDVRRKHPFPFGMRTSSSSPCFWATERVPAGLHTFQPRQPALTLPHSWSADRLHMMTLGSAEWSHALGNRASPLELQGLEPHHCGY", "length": 482, "header": "tr|A0A8V0YE15-1|A0A8V0YIR0_CHICK Computationally mapped isoform of DAP3 binding cell death enhancer 1 OS=Gallus gallus OX=9031 GN=DELE PE=4 SV=1 CANONICAL=A0A8V0YIR0-1" }, "locus": { "chromosome": "13", "start_pos": 2017692, "end_pos": 2002209, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027790.1", "url": "https://www.ensembl.org/id/ENSGALT00010027790.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015929.1", "url": "https://www.ensembl.org/id/ENSGALP00010015929.1" } ] } }, { "isoform_ac": "A0A8V0YIR0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIR0/entry#A0A8V0YIR0-1", "sequence": { "sequence": "MTRCYLYSCRLWHASCLPHRDAPRQAEGLCPQSPRSAAQPPAPRRFIPLSYRGPTARPSPGAHETTPSPGALRARAFPLLAAAPGPGPPRRSRAVLKGGQGAPAPLYASRRSCRHSPAGTPRRSPVSRPLYGHEEPLCSAVAEQRALSMVPRAACGGCCWAAAASRAACCRPPAPRPPPPPTLPTAAAPRGECGPRPSRRAAACPARPSRREGRRHRLVFCRCCGAPGCQHGGARDGREREGWRQPLPGLVPRYSVLDAVTWGALAALLLQLVRQISWLRSLPDARREPRPPWLPSLPAQHTVVSDASAGLPCAQLGPCFLQKAEVAPENSSSSFPLGPGDSQLWAEEGEFPVPQCSSPRPVPRSTKENPAKREHLEEAAFQLQQIFRVDISIAFNILGIESMRAGHYQIGYTCFKLAADRGYSKAQFNVGLCYEHGRGTEKDLEKAAFYYYRAASSCHPMAQYRYARCLLCHSPENEWHRLQKAVTFLEQAAVAGLTEAQAYLGVFYMRGLQPKEKKGLKYLLLAAKNGDAQSRYHVGVCYEKGLGVQQNLAEAMRHYQQSAAAGNRNAQERLRVIEEEMEDVRRKHPFPFGMRTSSSSPCFWATERVPAGLHTFQPRQPALTLPHSWSADRLHMMTLGSAEWSHALGNRASPLELQGLEPHHCGY", "length": 667, "header": "tr|A0A8V0YIR0-1|A0A8V0YIR0_CHICK Isoform 1 of DAP3 binding cell death enhancer 1 OS=Gallus gallus OX=9031 GN=DELE PE=4 SV=1 CANONICAL=A0A8V0YIR0-1" }, "locus": { "chromosome": "13", "start_pos": 2017692, "end_pos": 2001641, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027794.1", "url": "https://www.ensembl.org/id/ENSGALT00010027794.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015932.1", "url": "https://www.ensembl.org/id/ENSGALP00010015932.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:769453", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:769453", "resource": "KEGG Pathway" }, { "id": "R-GGA-9840373", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9840373", "resource": "Reactome", "description": "Cellular response to mitochondrial stress" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIR0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIR0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "protein serine/threonine kinase activator activity", "id": "GO:0043539", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043539", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIR0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIR0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "HRI-mediated signaling", "id": "GO:0140468", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140468", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIR0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIR0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 330, "end_pos": 332, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 330, "end_pos": 332 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YIR4-1", "uniprot_ac": "A0A8V0YIR4", "uniprot_id": "A0A8V0YIR4_CHICK", "mass": { "chemical_mass": 144336.0, "monoisotopic_mass": 144336.0 }, "refseq": { "ac": "XP_025003819", "name": "matrilin-2 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025003819" }, "gene_names": [ { "name": "MATN2", "type": "recommended", "evidence": [ { "id": "A0A8V0YIR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIR4" } ] }, { "name": "MATN2", "type": "synonym", "evidence": [ { "id": "XP_025003819", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025003819" } ] } ], "protein_names": [ { "name": "Matrilin 2", "type": "synonym", "evidence": [ { "id": "A0A8V0YIR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIR4/entry#names_and_taxonomy" } ] }, { "name": "matrilin-2 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_025003819", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025003819" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052533.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_025003819.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_025003819", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025003819" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIR4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIR4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MATN2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIR4", "locus": { "chromosome": "2", "start_pos": 127054849, "end_pos": 126985290, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010011628", "url": "https://www.ensembl.org/id/ENSGALG00010011628" } ] } } ], "crossref": [ { "id": "A0A8V0YIR4", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YIR4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000044675", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000044675", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00054", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00054", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd01475", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01475", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "426584", "url": "https://www.ncbi.nlm.nih.gov/gene/426584", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000152", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000152", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000742", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000742", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001881", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001881", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002035", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002035", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009030", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009030", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013032", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013032", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019466", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019466", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036337", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036337", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036465", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036465", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050525", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050525", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050751", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050751", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052235", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052235", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:426584", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:426584", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CATEDHA", "url": "https://omabrowser.org/oma/group/CATEDHA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q3A488", "url": "https://www.orthodb.org/?gene=A0A3Q3A488", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YBT1", "url": "https://www.orthodb.org/?gene=A0A8V0YBT1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YE20", "url": "https://www.orthodb.org/?gene=A0A8V0YE20", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YE24", "url": "https://www.orthodb.org/?gene=A0A8V0YE24", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YE29", "url": "https://www.orthodb.org/?gene=A0A8V0YE29", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YE34", "url": "https://www.orthodb.org/?gene=A0A8V0YE34", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YIR4", "url": "https://www.orthodb.org/?gene=A0A8V0YIR4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24020", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24020", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24020:SF35", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24020:SF35", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24034", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24034", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24034:SF155", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24034:SF155", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24050", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24050", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24050:SF29", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24050:SF29", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00092", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00092", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF10393", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10393", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12661", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12661", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14670", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14670", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_025003819", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025003819", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q3A488", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3A488", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q3A488-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3A488-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YBT1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBT1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YBT1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBT1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YE20", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE20", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YE20-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE20-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YE24", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE24", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YE24-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE24-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YE29", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE29", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YE29-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE29-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YE34", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE34", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YE34-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE34-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YIR4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIR4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YIR4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIR4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSLYFLKMKTMIAYYFLLFGHALLCTVSIMAKDLPVGHFTRRRDVSSQSLLENTCNNKRLDLVFIIDSSRSVRPYDFEKVKEFILTILQFLDVSPDATRVGLIQYGSTVKHEFSLKTFRRKQEIERAVRRMMHLATGTMTGLAIQYAVNIAFSESEGARPLNQNVPRIIMIVTDGRPQDPVGEIAAKARNSGILIFAIGVGRVDMNTLKSIGSEPHEEHIFLVANFSQIETLTSVFQTKLCVPHMCSIAEHRCDHFCINTPGSYVCRCKQGYILNADQRTCSTQDLCAVEKHNCEQICVNTPGSYVCQCYEGYELDADGKNCVVVDYCAVDNQGCQHECVNTEDSYYCRCHPGFILNADKRTCRRPDYCALQDHGCEQECVNTDDSYFCRCQEGFRLNPDKKTCKRVDHCAENDHGCEQLCLNTDDSYVCQCSEGFVINEDLRTCSRVDYCVLSDHGCEHLCINGDKSYTCQCFEGYRLRNDGKTCKRKNVCKSVNHGCEHVCVSTDNSYICKCREGFILRDDGKTCRRQDICKSISHGCEHICVNKDDSYACECHEGFLLREDGKTCRYKDICSSVDHGCEHVCVNADESYICQCYEGFALRQDGKTCRNKDVCNSVDHGCEHVCVNTDNSYICQCYEGFVLREDEKTCESKDICKSVNHGCEHLCVNGDDSYTCQCHDGFVLRQDGKTCRNKDICKSVNHGCEHACVNAGDTFVCKCREGFLLREDGKTCRNKDLCKSVNHGCEHVCVNTDDSYICKCHDGFLLREDGKTCKNKDICNSINHGCEQVCVNSGESYVCKCHENFVLKEDGKTCKYKDVCKSVNHGCEHICVNTEDSYICKCHDDFILREDGKTCRSKNICKTVNHGCEHVCVPAGDSYACQCHKGFTLRRDRKTCRNKDLCKSIDHGCEHVCISNNNSYSCQCREGFVLRQDGKTCRSKDVCKSVAHGCEHICVNNDDSYICKCQEGYVLKEDQKTCRRCTEGPVDLVFVIDGSKSLGEDNFEIVKQFVSGILDTLEISPKAARVGLLQYSSEVRTEFTLRRFSTAKDMKKAVSQMKYMGRGSMTGLALKQMFERSFTETEGARPLSANIPRISIVFTDGRAQDEVSEWAARAKRSGIIIYAIGIGKAIEEELLEIASEPSYKHLFYAEDFTAMEDISEELKVQICEALRNSAHQQHLSSGRLHRTNPQPSGPESTTVEITDVLACPSLAIQHKYLFEDSQSHSTRTTAKTSKDQCKCENLVTFQNYATNEVRRLTQRLEEMTKRMEDLENRLKY", "length": 1276, "header": "tr|A0A8V0YIR4-1|A0A8V0YIR4_CHICK Isoform 1 of Matrilin 2 OS=Gallus gallus OX=9031 GN=MATN2 PE=1 SV=1 CANONICAL=A0A8V0YIR4-1" }, "isoforms": [ { "isoform_ac": "A0A3Q3A488-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIR4/entry#A0A3Q3A488-1", "sequence": { "sequence": "MSLYFLKMKTMIAYYFLLFGHALLCTVSIMAKDLPVGHFTRRRDVSSQSLLENTCNNKRLDLVFIIDSSRSVRPYDFEKVKEFILTILQFLDVSPDATRVGLIQYGSTVKHEFSLKTFRRKQEIERAVRRMMHLATGTMTGLAIQYAVNIAFSESEGARPLNQNVPRIIMIVTDGRPQDPVGEIAAKARNSGILIFAIGVGRVDMNTLKSIGSEPHEEHIFLVANFSQIETLTSVFQTKLCDGGIWRSQGLLLPPFLRECLHNICCFKN", "length": 269, "header": "tr|A0A3Q3A488-1|A0A3Q3A488_CHICK Computationally mapped isoform of Matrilin 2 OS=Gallus gallus OX=9031 GN=MATN2 PE=4 SV=1 CANONICAL=A0A8V0YIR4-1" }, "locus": { "chromosome": "2", "start_pos": 127010404, "end_pos": 126996113, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027791.1", "url": "https://www.ensembl.org/id/ENSGALT00010027791.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015930.1", "url": "https://www.ensembl.org/id/ENSGALP00010015930.1" } ] } }, { "isoform_ac": "A0A8V0YBT1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIR4/entry#A0A8V0YBT1-1", "sequence": { "sequence": "MSLYFLKMKTMIAYYFLLFGHALLCTVSIMAKDLPVGHFTRRRDVSSQSLLENTCNNKRLDLVFIIDSSRSVRPYDFEKVKEFILTILQFLDVSPDATRVGLIQYGSTVKHEFSLKTFRRKQEIERAVRRMMHLATGTMTGLAIQYAVNIAFSESEGARPLNQNVPRIIMIVTDGRPQDPVGEIAAKARNSGILIFAIGVGRVDMNTLKSIGSEPHEEHIFLVANFSQIETLTSVFQTKLYGGIWRSQGLLLPPFLRECLHNICCFKN", "length": 268, "header": "tr|A0A8V0YBT1-1|A0A8V0YBT1_CHICK Computationally mapped isoform of Matrilin 2 OS=Gallus gallus OX=9031 GN=MATN2 PE=4 SV=1 CANONICAL=A0A8V0YIR4-1" }, "locus": { "chromosome": "2", "start_pos": 127010404, "end_pos": 126996113, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027787.1", "url": "https://www.ensembl.org/id/ENSGALT00010027787.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015928.1", "url": "https://www.ensembl.org/id/ENSGALP00010015928.1" } ] } }, { "isoform_ac": "A0A8V0YE20-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIR4/entry#A0A8V0YE20-1", "sequence": { "sequence": "MSLYFLKMKTMIAYYFLLFGHALLCTVSIMAKDLPVGHFTRRRDVSSQSLLENTCNNKRLDLVFIIDSSRSVRPYDFEKVKEFILTILQFLDVSPDATRVGLIQYGSTVKHEFSLKTFRRKQEIERAVRRMMHLATGTMTGLAIQYAVNIAFSESEGARPLNQNVPRIIMIVTDGRPQDPVGEIAAKARNSGILIFAIGVGRVDMNTLKSIGSEPHEEHIFLVANFSQIETLTSVFQTKLCVPHMCSIAEHRCDHFCINTPGSYVCRCKQGYILNADQRTCSTQDLCAVEKHNCEQICVNTPGSYVCQCYEGYELDADGKNCVVVDYCAVDNQGCQHECVNTEDSYYCRCHPGFILNADKRTCRRPDYCALQDHGCEQECVNTDDSYFCRCQEGFRLNPDKKTCKRVDHCAENDHGCEQLCLNTDDSYVCQCSEGFVINEDLRTCSRVDYCVLSDHGCEHLCINGDKSYTCQCFEGYRLRNDGKTCKRKNVCKSVNHGCEHVCVSTDNSYICKCREGFILRDDGKTCRRQDICKSISHGCEHICVNKDDSYACECHEGFLLREDGKTCRYKDICSSVDHGCEHVCVNADESYICQCYEGFALRQDGKTCRNKDVCNSVDHGCEHVCVNTDNSYICQCYEGFVLREDEKTCESKDICKSVNHGCEHLCVNGDDSYTCQCHDGFVLRQDGKTCRNKDICKSVNHGCEHACVNAGDTFVCKCREGFLLREDGKTCRNKDLCKSVNHGCEHVCVNTDDSYICKCHDGFLLREDGKTCKNKDICNSINHGCEQVCVNSGESYVCKCHENFVLKEDGKTCKYKDVCKSVNHGCEHICVNTEDSYICKCHDDFILREDGKTCRSKNICKTVNHGCEHVCVPAGDSYACQCHKGFTLRRDRKTCRNKDLCKSIDHGCEHVCISNNNSYSCQCREGFVLRQDGKTCRRCTEGPVDLVFVIDGSKSLGEDNFEIVKQFVSGILDTLEISPKAARVGLLQYSSEVRTEFTLRRFSTAKDMKKAVSQMKYMGRGSMTGLALKQMFERSFTETEGARPLSANIPRISIVFTDGRAQDEVSEWAARAKRSGIIIYAIGIGKAIEEELLEIASEPSYKHLFYAEDFTAMEDISEELKVQICEAKTSKDQCKCENLVTFQNYATNEVRRLTQRLEEMTKRMEDLENRLKY", "length": 1174, "header": "tr|A0A8V0YE20-1|A0A8V0YIR4_CHICK Computationally mapped isoform of Matrilin 2 OS=Gallus gallus OX=9031 GN=MATN2 PE=1 SV=1 CANONICAL=A0A8V0YIR4-1" }, "locus": { "chromosome": "2", "start_pos": 127054569, "end_pos": 126996113, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027797.1", "url": "https://www.ensembl.org/id/ENSGALT00010027797.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015934.1", "url": "https://www.ensembl.org/id/ENSGALP00010015934.1" } ] } }, { "isoform_ac": "A0A8V0YE24-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIR4/entry#A0A8V0YE24-1", "sequence": { "sequence": "MSLYFLKMKTMIAYYFLLFGHALLCTVSIMAKDLPVGHFTRRRDVSSQSLLENTCNNKRLDLVFIIDSSRSVRPYDFEKVKEFILTILQFLDVSPDATRVGLIQYGSTVKHEFSLKTFRRKQEIERAVRRMMHLATGTMTGLAIQYAVNIAFSESEGARPLNQNVPRIIMIVTDGRPQDPVGEIAAKARNSGILIFAIGVGRVDMNTLKSIGSEPHEEHIFLVANFSQIETLTSVFQTKLCVPHMCSIAEHRCDHFCINTPGSYVCRCKQGYILNADQRTCSTQDLCAVEKHNCEQICVNTPGSYVCQCYEGYELDADGKNCVVVDYCAVDNQGCQHECVNTEDSYYCRCHPGFILNADKRTCRRPDYCALQDHGCEQECVNTDDSYFCRCQEGFRLNPDKKTCKRVDHCAENDHGCEQLCLNTDDSYVCQCSEGFVINEDLRTCSRVDYCVLSDHGCEHLCINGDKSYTCQCFEGYRLRNDGKTCKRKNVCKSVNHGCEHVCVSTDNSYICKCREGFILRDDGKTCRRQDICKSISHGCEHICVNKDDSYACECHEGFLLREDGKTCRYKDICSSVDHGCEHVCVNADESYICQCYEGFALRQDGKTCRNKDVCNSVDHGCEHVCVNTDNSYICQCYEGFVLREDEKTCESKDICKSVNHGCEHLCVNGDDSYTCQCHDGFVLRQDGKTCRNKDICKSVNHGCEHACVNAGDTFVCKCREGFLLREDGKTCRNKDLCKSVNHGCEHVCVNTDDSYICKCHDGFLLREDGKTCKNKDICNSINHGCEQVCVNSGESYVCKCHENFVLKEDGKTCKYKDVCKSVNHGCEHICVNTEDSYICKCHDDFILREDGKTCRSKNICKTVNHGCEHVCVPAGDSYACQCHKGFTLRRDRKTCRNKDLCKSIDHGCEHVCISNNNSYSCQCREGFVLRQDGKTCRSKDVCKSVAHGCEHICVNNDDSYICKCQEGYVLKEDQKTCRRCTEGPVDLVFVIDGSKSLGEDNFEIVKQFVSGILDTLEISPKAARVGLLQYSSEVRTEFTLRRFSTAKDMKKAVSQMKYMGRGSMTGLALKQMFERSFTETEGARPLSANIPRISIVFTDGRAQDEVSEWAARAKRSGIIIYAIGIGKAIEEELLEIASEPSYKHLFYAEDFTAMEDISEELKVQICEALRNSAHQQHLSSGRLHRTNPQPSAKTSKDQCKCENLVTFQNYATNEVRRLTQRLEEMTKRMEDLENRLKY", "length": 1239, "header": "tr|A0A8V0YE24-1|A0A8V0YIR4_CHICK Computationally mapped isoform of Matrilin 2 OS=Gallus gallus OX=9031 GN=MATN2 PE=1 SV=1 CANONICAL=A0A8V0YIR4-1" }, "locus": { "chromosome": "2", "start_pos": 127054569, "end_pos": 126996113, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027802.1", "url": "https://www.ensembl.org/id/ENSGALT00010027802.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015939.1", "url": "https://www.ensembl.org/id/ENSGALP00010015939.1" } ] } }, { "isoform_ac": "A0A8V0YE29-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIR4/entry#A0A8V0YE29-1", "sequence": { "sequence": "MSLYFLKMKTMIAYYFLLFGHALLCTVSIMAKDLPVGHFTRRRDVSSQSLLENTCNNKRLDLVFIIDSSRSVRPYDFEKVKEFILTILQFLDVSPDATRVGLIQYGSTVKHEFSLKTFRRKQEIERAVRRMMHLATGTMTGLAIQYAVNIAFSESEGARPLNQNVPRIIMIVTDGRPQDPVGEIAAKARNSGILIFAIGVGRVDMNTLKSIGSEPHEEHIFLVANFSQIETLTSVFQTKLCVPHMCSIAEHRCDHFCINTPGSYVCRCKQGYILNADQRTCSTQDLCAVEKHNCEQICVNTPGSYVCQCYEGYELDADGKNCVVVDYCAVDNQGCQHECVNTEDSYYCRCHPGFILNADKRTCRRPDYCALQDHGCEQECVNTDDSYFCRCQEGFRLNPDKKTCKRVDHCAENDHGCEQLCLNTDDSYVCQCSEGFVINEDLRTCSRVDYCVLSDHGCEHLCINGDKSYTCQCFEGYRLRNDGKTCKRKNVCKSVNHGCEHVCVSTDNSYICKCREGFILRDDGKTCRNKDICSSVDHGCEHVCVNADESYICQCYEGFALRQDGKTCRNKDVCNSVDHGCEHVCVNTDNSYICQCYEGFVLREDEKTCESKDICKSVNHGCEHLCVNGDDSYTCQCHDGFVLRQDGKTCRNKDICKSVNHGCEHACVNAGDTFVCKCREGFLLREDGKTCRNKDLCKSVNHGCEHVCVNTDDSYICKCHDGFLLREDGKTCKNKDICNSINHGCEQVCVNSGESYVCKCHENFVLKEDGKTCKYKDVCKSVNHGCEHICVNTEDSYICKCHDDFILREDGKTCRSKNICKTVNHGCEHVCVPAGDSYACQCHKGFTLRRDRKTCRNKDLCKSIDHGCEHVCISNNNSYSCQCREGFVLRQDGKTCRSKDVCKSVAHGCEHICVNNDDSYICKCQEGYVLKEDQKTCRRCTEGPVDLVFVIDGSKSLGEDNFEIVKQFVSGILDTLEISPKAARVGLLQYSSEVRTEFTLRRFSTAKDMKKAVSQMKYMGRGSMTGLALKQMFERSFTETEGARPLSANIPRISIVFTDGRAQDEVSEWAARAKRSGIIIYAIGIGKAIEEELLEIASEPSYKHLFYAEDFTAMEDISEELKVQICEALRNSAHQQHLSSGRLHRTNPQPSGPESTTVEITDVLACPSLAIQHKYLFEDSQSHSTRTTAKTSKDQCKCENLVTFQNYATNEVRRLTQRLEEMTKRMEDLENRLKY", "length": 1235, "header": "tr|A0A8V0YE29-1|A0A8V0YIR4_CHICK Computationally mapped isoform of Matrilin 2 OS=Gallus gallus OX=9031 GN=MATN2 PE=1 SV=1 CANONICAL=A0A8V0YIR4-1" }, "locus": { "chromosome": "2", "start_pos": 127054569, "end_pos": 126996113, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027810.1", "url": "https://www.ensembl.org/id/ENSGALT00010027810.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015944.1", "url": "https://www.ensembl.org/id/ENSGALP00010015944.1" } ] } }, { "isoform_ac": "A0A8V0YE34-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIR4/entry#A0A8V0YE34-1", "sequence": { "sequence": "MSLYFLKMKTMIAYYFLLFGHALLCTVSIMAKDLPVGHFTRRRDVSSQSLLENTCNNKRLDLVFIIDSSRSVRPYDFEKVKEFILTILQFLDVSPDATRVGLIQYGSTVKHEFSLKTFRRKQEIERAVRRMMHLATGTMTGLAIQYAVNIAFSESEGARPLNQNVPRIIMIVTDGRPQDPVGEIAAKARNSGILIFAIGVGRVDMNTLKSIGSEPHEEHIFLVANFSQIETLTSVFQTKLCVPHMCSIAEHRCDHFCINTPGSYVCRCKQGYILNADQRTCSTQDLCAVEKHNCEQICVNTPGSYVCQCYEGYELDADGKNCVVVDYCAVDNQGCQHECVNTEDSYYCRCHPGFILNADKRTCRRPDYCALQDHGCEQECVNTDDSYFCRCQEGFRLNPDKKTCKRVDHCAENDHGCEQLCLNTDDSYVCQCSEGFVINEDLRTCSRVDYCVLSDHGCEHLCINGDKSYTCQCFEGYRLRNDGKTCKRKNVCKSVNHGCEHVCVSTDNSYICKCREGFILRDDGKTCRRQDICKSISHGCEHICVNKDDSYACECHEGFLLREDGKTCRYKDICSSVDHGCEHVCVNADESYICQCYEGFALRQDGKTCRNKDVCNSVDHGCEHVCVNTDNSYICQCYEGFVLREDEKTCESKDICKSVNHGCEHLCVNGDDSYTCQCHDGFVLRQDGKTCRNKDICKSVNHGCEHACVNAGDTFVCKCREGFLLREDGKTCRNKDLCKSVNHGCEHVCVNTDDSYICKCHDGFLLREDGKTCKNKDICNSINHGCEQVCVNSGESYVCKCHENFVLKEDGKTCKYKDVCKSVNHGCEHICVNTEDSYICKCHDDFILREDGKTCRSKNICKTVNHGCEHVCVPAGDSYACQCHKGFTLRRDRKTCRNKDLCKSIDHGCEHVCISNNNSYSCQCREGFVLRQDGKTCRSKDVCKSVAHGCEHICVNNDDSYICKCQEGYVLKEDQKTCRRCTEGPVDLVFVIDGSKSLGEDNFEIVKQFVSGILDTLEISPKAARVGLLQYSSEVRTEFTLRRFSTAKDMKKAVSQMKYMGRGSMTGLALKQMFERSFTETEGARPLSANIPRISIVFTDGRAQDEVSEWAARAKRSGIIIYAIGIGKAIEEELLEIASEPSYKHLFYAEDFTAMEDISEELKVQICEAKTSKDQCKCENLVTFQNYATNEVRRLTQRLEEMTKRMEDLENRLKY", "length": 1215, "header": "tr|A0A8V0YE34-1|A0A8V0YIR4_CHICK Computationally mapped isoform of Matrilin 2 OS=Gallus gallus OX=9031 GN=MATN2 PE=1 SV=1 CANONICAL=A0A8V0YIR4-1" }, "locus": { "chromosome": "2", "start_pos": 127054569, "end_pos": 126996113, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027815.1", "url": "https://www.ensembl.org/id/ENSGALT00010027815.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015949.1", "url": "https://www.ensembl.org/id/ENSGALP00010015949.1" } ] } }, { "isoform_ac": "A0A8V0YIR4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIR4/entry#A0A8V0YIR4-1", "sequence": { "sequence": "MSLYFLKMKTMIAYYFLLFGHALLCTVSIMAKDLPVGHFTRRRDVSSQSLLENTCNNKRLDLVFIIDSSRSVRPYDFEKVKEFILTILQFLDVSPDATRVGLIQYGSTVKHEFSLKTFRRKQEIERAVRRMMHLATGTMTGLAIQYAVNIAFSESEGARPLNQNVPRIIMIVTDGRPQDPVGEIAAKARNSGILIFAIGVGRVDMNTLKSIGSEPHEEHIFLVANFSQIETLTSVFQTKLCVPHMCSIAEHRCDHFCINTPGSYVCRCKQGYILNADQRTCSTQDLCAVEKHNCEQICVNTPGSYVCQCYEGYELDADGKNCVVVDYCAVDNQGCQHECVNTEDSYYCRCHPGFILNADKRTCRRPDYCALQDHGCEQECVNTDDSYFCRCQEGFRLNPDKKTCKRVDHCAENDHGCEQLCLNTDDSYVCQCSEGFVINEDLRTCSRVDYCVLSDHGCEHLCINGDKSYTCQCFEGYRLRNDGKTCKRKNVCKSVNHGCEHVCVSTDNSYICKCREGFILRDDGKTCRRQDICKSISHGCEHICVNKDDSYACECHEGFLLREDGKTCRYKDICSSVDHGCEHVCVNADESYICQCYEGFALRQDGKTCRNKDVCNSVDHGCEHVCVNTDNSYICQCYEGFVLREDEKTCESKDICKSVNHGCEHLCVNGDDSYTCQCHDGFVLRQDGKTCRNKDICKSVNHGCEHACVNAGDTFVCKCREGFLLREDGKTCRNKDLCKSVNHGCEHVCVNTDDSYICKCHDGFLLREDGKTCKNKDICNSINHGCEQVCVNSGESYVCKCHENFVLKEDGKTCKYKDVCKSVNHGCEHICVNTEDSYICKCHDDFILREDGKTCRSKNICKTVNHGCEHVCVPAGDSYACQCHKGFTLRRDRKTCRNKDLCKSIDHGCEHVCISNNNSYSCQCREGFVLRQDGKTCRSKDVCKSVAHGCEHICVNNDDSYICKCQEGYVLKEDQKTCRRCTEGPVDLVFVIDGSKSLGEDNFEIVKQFVSGILDTLEISPKAARVGLLQYSSEVRTEFTLRRFSTAKDMKKAVSQMKYMGRGSMTGLALKQMFERSFTETEGARPLSANIPRISIVFTDGRAQDEVSEWAARAKRSGIIIYAIGIGKAIEEELLEIASEPSYKHLFYAEDFTAMEDISEELKVQICEALRNSAHQQHLSSGRLHRTNPQPSGPESTTVEITDVLACPSLAIQHKYLFEDSQSHSTRTTAKTSKDQCKCENLVTFQNYATNEVRRLTQRLEEMTKRMEDLENRLKY", "length": 1276, "header": "tr|A0A8V0YIR4-1|A0A8V0YIR4_CHICK Isoform 1 of Matrilin 2 OS=Gallus gallus OX=9031 GN=MATN2 PE=1 SV=1 CANONICAL=A0A8V0YIR4-1" }, "locus": { "chromosome": "2", "start_pos": 127054569, "end_pos": 126996113, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027800.1", "url": "https://www.ensembl.org/id/ENSGALT00010027800.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015937.1", "url": "https://www.ensembl.org/id/ENSGALP00010015937.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:426584", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:426584", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "F1LXS3-1", "protein_name": "Matrilin-2", "gene_name": "Matn2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEKMLVGCLLMLGQLLLVLPVGARERRPQDRFPSRGRRMHPQTALLESSCENKRADLVFIIDSSRSVNTHDYAKVKEFILDILQFLDIGPDITRVGLLQYGSTVKNEFSLKTFKRKSDVERAVKRMRHLSTGTMTGLAIQYALNIAFSEAEGARPLRENVPRVIMIVTDGRPQDSVAEVASKARNTGILIFAIGVGQVDLNTLKAIGSEPHKDHVFLVANFSQIESLTSVFQNKLCTVHMCSVLEHNCAHFCINTPGSYTCKCKQGYILGPDQKTCRIQDLCATEDHGCEQLCVNMLGSFVCHCYSGYTLAEDGKQCTAVDYCASENHRCEHECVNAEGSYLCRCHEGFALNVDKKTCSKIDYCASSDHGCQHECVNAQTSAFCRCLKGFMLNPDRKTCRRINYCALNKPGCEHECVNTEEGHYCRCRRGYTLDPNGKTCSRVDHCAQQDHGCEQLCLNTEESFVCQCSEGFLINDDLKTCSRADYCLLSNHGCEYSCVNTDKSFACQCPEGHVLRSDGKTCAKLDSCALGDHGCEHSCVSSEDSFVCRCFEGYVLRDDGKTCRREDVCQAVDHGCEHLCVNSGESYICKCLEGFRLAEDGKRCRRKDVCKSIQHGCEHICVNNGNSYLCRCSEGFVLAEDGRHCKRCTEGPIDLVFVIDGSKSLGEENFEIVKHFVTGIIDSLAVSPKAARVGLLQYSTQVRTEFTLKGFSSAKDMKKAVAHMKYMGKGSMTGLALKHMYERSFTQVEGARPLSTRVPRAAIVFTDGRAQDDVSEWARKAKANGITMYAVGIGKAIEEELQEIASEPIDKHLFYAEDFSTMGEISEKLKLGICEALEDSDGRQDSPAGDLPRQVHQPTVQHRYLFEDNLSRSTQKLLHSTQSSGNPREETQDQCKCENLIQFQNLANEEKK", "length": 912 }, "evidence": [ { "id": "A0A8V0YIR4", "url": "https://omabrowser.org/oma/group/A0A8V0YIR4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O00339-1", "protein_name": "Matrilin-2", "gene_name": "MATN2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEKMLAGCFLLILGQIVLLPAEARERSRGRSISRGRHARTHPQTALLESSCENKRADLVFIIDSSRSVNTHDYAKVKEFIVDILQFLDIGPDVTRVGLLQYGSTVKNEFSLKTFKRKSEVERAVKRMRHLSTGTMTGLAIQYALNIAFSEAEGARPLRENVPRVIMIVTDGRPQDSVAEVAAKARDTGILIFAIGVGQVDFNTLKSIGSEPHEDHVFLVANFSQIETLTSVFQKKLCTAHMCSTLEHNCAHFCINIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCEQLCVNVPGSFVCQCYSGYALAEDGKRCVAVDYCASENHGCEHECVNADGSYLCQCHEGFALNPDKKTCTKIDYCASSNHGCQHECVNTDDSYSCHCLKGFTLNPDKKTCRRINYCALNKPGCEHECVNMEESYYCRCHRGYTLDPNGKTCSRVDHCAQQDHGCEQLCLNTEDSFVCQCSEGFLINEDLKTCSRVDYCLLSDHGCEYSCVNMDRSFACQCPEGHVLRSDGKTCAKLDSCALGDHGCEHSCVSSEDSFVCQCFEGYILREDGKTCRRKDVCQAIDHGCEHICVNSDDSYTCECLEGFRLAEDGKRCRRKDVCKSTHHGCEHICVNNGNSYICKCSEGFVLAEDGRRCKKCTEGPIDLVFVIDGSKSLGEENFEVVKQFVTGIIDSLTISPKAARVGLLQYSTQVHTEFTLRNFNSAKDMKKAVAHMKYMGKGSMTGLALKHMFERSFTQGEGARPLSTRVPRAAIVFTDGRAQDDVSEWASKAKANGITMYAVGVGKAIEEELQEIASEPTNKHLFYAEDFSTMDEISEKLKKGICEALEDSDGRQDSPAGELPKTVQQPTESEPVTINIQDLLSCSNFAVQHRYLFEEDNLLRSTQKLSHSTKPSGSPLEEKHDQCKCENLIMFQNLANEEVRKLTQRLEEMTQRMEALENRLRYR", "length": 956 }, "evidence": [ { "id": "A0A8V0YIR4", "url": "https://omabrowser.org/oma/group/A0A8V0YIR4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "O08746-1", "protein_name": "Matrilin-2", "gene_name": "Matn2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEKMLVGCLLMLGQLFLVLPVDGRERPQARFPSRGRHVRMYPQTALLESSCENKRADLVFIIDSSRSVNTYDYAKVKEFILDILQFLDIGPDVTRVGLLQYGSTVKNEFSLKTFKRKSEVERAVKRMRHLSTGTMTGLAIQYALNIAFSEAEGARPLRENVPRIIMIVTDGRPQDSVAEVAAKARNTGILIFAIGVGQVDLNTLKAIGSEPHKDHVFLVANFSQIESLTSVFQNKLCTVHMCSVLEHNCAHFCLNTPGSYICKCKQGYILSTDQKTCRIQDLCATEDHGCEQLCVNMLGSFVCQCYSGYTLAEDGKRCTAVDYCASENHGCEHECVNAESSYLCRCHEGFALNSDKKTCSKIDYCASSNHGCQHECVNAQTSALCRCLKGFMLNPDRKTCRRINYCALNKPGCEHECVNTEEGHYCRCRQGYNLDPNGKTCSRVDHCAQQDHGCEQLCLNTEESFVCQCSEGFLINDDLKTCSRADYCLLSNHGCEYSCVNTDKSFACQCPEGHVLRSDGKTCAKLDSCALGDHGCEHSCVSSEDSFVCQCFEGYILRDDGKTCRRKDVCQDVNHGCEHLCVNSGESYVCKCLEGFRLAEDGKRCRRKNVCKSTQHGCEHMCVNNGNSYLCRCSEGFVLAEDGKHCKRCTEGPIDLVFVIDGSKSLGEENFETVKHFVTGIIDSLAVSPKAARVGLLQYSTQVRTEFTLRGFSSAKEMKKAVTHMKYMGKGSMTGLALKHMFERSFTQVEGARPPSTQVPRVAIVFTDGRAQDDVSEWASKAKANGITMYAVGVGKAIEEELQEIASEPIDKHLFYAEDFSTMGEISEKLKEGICEALEDSGGRQDSAAWDLPQQAHQPTEPEPVTIKIKDLLSCSNFAVQHRFLFEEDNLSRSTQKLFHSTKSSGNPLEESQDQCKCENLILFQNVANEEVRKLTQRLEEMTQRMEALENRLKYR", "length": 956 }, "evidence": [ { "id": "A0A8V0YIR4", "url": "https://omabrowser.org/oma/group/A0A8V0YIR4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIR4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIR4" } ], "pmid": "" }, { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIR4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIR4" } ], "pmid": "" }, { "name": "extracellular matrix", "id": "GO:0031012", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031012", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIR4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIR4" } ], "pmid": "" }, { "name": "basement membrane", "id": "GO:0005604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005604", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIR4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIR4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIR4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIR4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 225, "end_pos": 227, "annotation": "n_glycosylation_sequon" }, { "start_pos": 917, "end_pos": 919, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YIR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIR4" }, { "id": "PS50026", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50026" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "EGF-like", "eco_id": "ECO_0000259", "start_pos": 324, "end_pos": 364, "start_aa": "Val", "end_aa": "Arg", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0YIR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIR4" }, { "id": "PS50234", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50234" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "VWFA", "eco_id": "ECO_0000259", "start_pos": 61, "end_pos": 240, "start_aa": "Asp", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 225, "end_pos": 227 }, { "start_pos": 917, "end_pos": 919 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YL57-1", "uniprot_ac": "A0A8V0YL57", "uniprot_id": "A0A8V0YL57_CHICK", "mass": { "chemical_mass": 101974.0, "monoisotopic_mass": 101974.0 }, "refseq": { "ac": "XP_004943165", "name": "WD repeat-containing protein 47", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004943165" }, "gene_names": [ { "name": "WDR47", "type": "recommended", "evidence": [ { "id": "A0A8V0YL57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL57" } ] }, { "name": "WDR47", "type": "synonym", "evidence": [ { "id": "XP_004943165", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004943165" } ] } ], "protein_names": [ { "name": "WD repeat domain 47", "type": "synonym", "evidence": [ { "id": "A0A8V0YL57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL57/entry#names_and_taxonomy" } ] }, { "name": "WD repeat-containing protein 47", "type": "synonym", "evidence": [ { "id": "XP_004943165", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004943165" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052539.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_004943165.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004943165", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004943165" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YL57", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL57" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "WDR47", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL57", "locus": { "chromosome": "8", "start_pos": 1356442, "end_pos": 1377865, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012113", "url": "https://www.ensembl.org/id/ENSGALG00010012113" } ] } } ], "crossref": [ { "id": "A0A8V0YL57", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YL57", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00200", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00200", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "424344", "url": "https://www.ncbi.nlm.nih.gov/gene/424344", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001680", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001680", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006594", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006594", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006595", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006595", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019775", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019775", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036322", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036322", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040067", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040067", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR054532", "url": "https://www.ebi.ac.uk/interpro/entry/IPR054532", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057749", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057749", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:424344", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424344", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HICPTPE", "url": "https://omabrowser.org/oma/group/HICPTPE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YE81", "url": "https://www.orthodb.org/?gene=A0A8V0YE81", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YL57", "url": "https://www.orthodb.org/?gene=A0A8V0YL57", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR19863", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19863", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19863:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19863:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00400", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00400", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17814", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17814", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25602", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25602", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_004943165", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004943165", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YE81", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE81", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YE81-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE81-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YL57", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL57", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YL57-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL57-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTAEETVNVKEAEIIKLILDFLNSRKLHISMLALEKESGVINGLFSDDMLFLRQLILDGQWDEVLQFIQPLECMEKFDKKRFRYIIMKQKFLEALCVNNAMSAEDEPQHLEFTMREAVQCLHALEEYCPSKEDYSKLCLLLTLPRLTNHAEFKDWNPSTARVHCFEEACVMVAEFIPADRKLSEAGFKASNNRLFQLVMKGLLYECCVEFCQSKATGEEITESEVLLGIDLLCGNGCDDLDLSLLSWLQNLPATVFSCAFEQKMLNIHVDKLLKPTKAAYADLLTPLISKLSPYPSSPMRRPQSADAYMTRSLNPALDGLSCGLTNHEKRITDLGTKTSPMSHSFANFHYPGVQNLSRSLMLENTECHSIFEESPERDTPVEPQHPIGSETLSQSVAPENEQVTGAQSQGSAKQEKNELRDSTEQFQEYYRQRLRYQQHLEQKEQQRQLYQQMLLEGGVNQEDGADQQQNLTEQFLNRSIQKLGELNIGMDSLGNDVQTLSQQCNGSKGNASTSLASNATSDVPQRMPTDGQSVNTSTPRKRGSANQIPFPEESPVQGNQIVSEHAVTQPQLDDSSGNLSRTRGDEDDKSKKQFICINTLEDTQAVRAVAFHPSGSLYAVGSNSKTLRVCAYPEVIDPSAYNIPKQPVVRFKRNKHHKGSIYCVAWSPCGQLLATGSNDKYVKVLPFNAETCNATGPDLEFSMHDGTIRDLAFMEGPESGGAILISAGAGDCNIYTTDCQRGQGLHALSGHTGHILALYTWSGWMIASGSQDKTVRFWDLRVPSCVRVVGTTFHGTGSAVASVAVDPSGRLLATGQEDSSCMLYDIRGGRMVQSYHPHASDVRSVRFSPGAHYLLTGSYDMKIKVTDLQGDLTKQLPLMVVGEHKDKVIQCRWHTQDLSFLSSSADRTVTLWTYNG", "length": 916, "header": "tr|A0A8V0YL57-1|A0A8V0YL57_CHICK Isoform 1 of WD repeat domain 47 OS=Gallus gallus OX=9031 GN=WDR47 PE=1 SV=1 CANONICAL=A0A8V0YL57-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YE81-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL57/entry#A0A8V0YE81-1", "sequence": { "sequence": "MTAEETVNVKEAEIIKLILDFLNSRKLHISMLALEKESGVINGLFSDDMLFLRQLILDGQWDEVLQFIQPLECMEKFDKKRFRYIIMKQKFLEALCVNNAMSAEDEPQHLEFTMREAVQCLHALEEYCPSKEDYSKLCLLLTLPRLTNHAEFKDWNPSTARVHCFEEACVMVAEFIPADRKLSEAGFKASNNRLFQLVMKGLLYECCVEFCQSKATGEEITESEVLLGIDLLCGNGCDDLDLSLLSWLQNLPATVFSCAFEQKMLNIHVDKLLKPTKAAYADLLTPLISKLSPYPSSPMRRPQSADAYMTRSLNPALDGLSCGLTNHEKRITDLGTKTSPMSHSFANFHYPGVQNLSRSLMLENTECHSIFEESPERDTPVEPQHPIGSETLSQSVAPENEQVTGAQSQGSAKQEKNELRDSTEQFQEYYRQRLRYQQHLEQKEQQRQLYQQMLLEGGVNQEDGADQQQNLTEQFLNRSIQKLGELNIGMDSLGNDVQTLSQQCNGSKGNASTSLASNATSDVPQRMPTDGQSVNTSTPRKRGSANQIPFPEESPVQGNQIVSEHAVTQPQLDDSSGNLSRTRGDEDDKSKKQFICINTLEDTQAVRAVAFHPSGSLYAVGSNSKTLRVCAYPEVIDPSAYNIPKQPVVRFKRNKHHKGSIYCVAWSPCGQLLATGSNDKYVKVLPFNAETCNATGPDLEFSMHDGTIRDLAFMEGPESGGAILISAGAGDCNIYTTDCQRGQGLHALSGHTGHILALYTWSGWMIASGSQDKTVRFWDLRVPSCVRVVGTTFHGTAASSYGGGRAQGQSYSMQMAYTRSFLLVIISRQNCNALDLQRLECN", "length": 842, "header": "tr|A0A8V0YE81-1|A0A8V0YL57_CHICK Computationally mapped isoform of WD repeat domain 47 OS=Gallus gallus OX=9031 GN=WDR47 PE=1 SV=1 CANONICAL=A0A8V0YL57-1" }, "locus": { "chromosome": "8", "start_pos": 1373231, "end_pos": 1357654, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029041.1", "url": "https://www.ensembl.org/id/ENSGALT00010029041.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016800.1", "url": "https://www.ensembl.org/id/ENSGALP00010016800.1" } ] } }, { "isoform_ac": "A0A8V0YL57-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL57/entry#A0A8V0YL57-1", "sequence": { "sequence": "MTAEETVNVKEAEIIKLILDFLNSRKLHISMLALEKESGVINGLFSDDMLFLRQLILDGQWDEVLQFIQPLECMEKFDKKRFRYIIMKQKFLEALCVNNAMSAEDEPQHLEFTMREAVQCLHALEEYCPSKEDYSKLCLLLTLPRLTNHAEFKDWNPSTARVHCFEEACVMVAEFIPADRKLSEAGFKASNNRLFQLVMKGLLYECCVEFCQSKATGEEITESEVLLGIDLLCGNGCDDLDLSLLSWLQNLPATVFSCAFEQKMLNIHVDKLLKPTKAAYADLLTPLISKLSPYPSSPMRRPQSADAYMTRSLNPALDGLSCGLTNHEKRITDLGTKTSPMSHSFANFHYPGVQNLSRSLMLENTECHSIFEESPERDTPVEPQHPIGSETLSQSVAPENEQVTGAQSQGSAKQEKNELRDSTEQFQEYYRQRLRYQQHLEQKEQQRQLYQQMLLEGGVNQEDGADQQQNLTEQFLNRSIQKLGELNIGMDSLGNDVQTLSQQCNGSKGNASTSLASNATSDVPQRMPTDGQSVNTSTPRKRGSANQIPFPEESPVQGNQIVSEHAVTQPQLDDSSGNLSRTRGDEDDKSKKQFICINTLEDTQAVRAVAFHPSGSLYAVGSNSKTLRVCAYPEVIDPSAYNIPKQPVVRFKRNKHHKGSIYCVAWSPCGQLLATGSNDKYVKVLPFNAETCNATGPDLEFSMHDGTIRDLAFMEGPESGGAILISAGAGDCNIYTTDCQRGQGLHALSGHTGHILALYTWSGWMIASGSQDKTVRFWDLRVPSCVRVVGTTFHGTGSAVASVAVDPSGRLLATGQEDSSCMLYDIRGGRMVQSYHPHASDVRSVRFSPGAHYLLTGSYDMKIKVTDLQGDLTKQLPLMVVGEHKDKVIQCRWHTQDLSFLSSSADRTVTLWTYNG", "length": 916, "header": "tr|A0A8V0YL57-1|A0A8V0YL57_CHICK Isoform 1 of WD repeat domain 47 OS=Gallus gallus OX=9031 GN=WDR47 PE=1 SV=1 CANONICAL=A0A8V0YL57-1" }, "locus": { "chromosome": "8", "start_pos": 1373231, "end_pos": 1357665, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029045.1", "url": "https://www.ensembl.org/id/ENSGALT00010029045.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016804.1", "url": "https://www.ensembl.org/id/ENSGALP00010016804.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:424344", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424344", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8M1QV96-1", "protein_name": "WD repeat-containing protein 47", "gene_name": "wdr47a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTAEEIINVKEVEIIKVMLDFLNSRKLHISMLALEKESGVINGLYSDDMLFLRQLILDGQWDEVLQFIQPLECLDKFDRKRFRYIVLKQKFLEALCVNNAMSAEDEPQHLELTMQEAVKCLHALEEFCPSKDDYSKLCLLLTLPRLTNHAEFKDWNPSTARVQCFEESCGMVAEFIPADRKLSEAGFRASSNRLFQLLIKGVLYECCVEFCQSKATGEEITESEVLLGIDMLCGNGCDDLDLSLLSWLQNLSPSVFSCAFEQKMLNIHVDRLVKPAKAAYADLLTPLISKLSPYPASPLRRPQSADTYMSRSLNPALDGLSYGLSQEKRGVTTDGGKTSPMSHSFANFQHMNRSVMMENSGCHSIFEESPESSRTETPSDKMMSSPGPQNSRPASAPGQDAPTPGSEEKNELRDSTDQFQEYYRQRLRVQQHLEQKQQQRELYQQMLREGGVQQHEAPPTAKHNLTEAFLTRSIQRLEELNVGMDDLGEEVQALSQQCKEGTNSNGEVGDASATPQTQDGGGGASSVMTSTPQRSASQSGFPPSSQSPVLTKSAQKDKTGQNDSLTRSKGPEKEKTKAKFVMVNTLEDTQAVRAVAFHPTGALYAVGSNSKTLRVCAYPDTLDTSGTGTNKPPVIRFKRNKHHKGSIYCVAWSPCGQLLATGSNDKYVKVLPFNPETCNATGPDLEFSMHDGTIRDLAFMEGPECGGAILISAGAGDCNIYTTDCQRGQGLHALSGHTGHILSLYTWGGWMIASGSQDKTVRFWDLRVPSCVRVVGTAFQGSGSPVASVAVDPSGRLLATGQEDSSCMLYDIRGGRMVQTYKPHSSDVRSVRFSPGAHYLLTGSYDNKVIVTDLQGDLTKQLPLTVVGEHGDKVIQCRWHSHHLSFLSSSADRTVTLWTQAT", "length": 902 }, "evidence": [ { "id": "A0A8V0YL57", "url": "https://omabrowser.org/oma/group/A0A8V0YL57/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "G3V9M3-1", "protein_name": "WD repeat domain 47", "gene_name": "Wdr47", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTAEETVNVKEVEIIKLILDFLNSKKLHISMLALEKESGVINGLFSDDMLFLRQLILDGQWDEVLQFIQPLECMEKFDKKRFRYIILKQKFLEALCVNNAMSAEDEPQHVRFLFLKLEFTMQEAVQCLHALEEYCPSKDDYSKLCLLLTLPRLTNHAEFKDWNPSTARVHCFEEVCVMVAEFIPADRKLSEAGFKASNNRLFQLVMKGLLYECCVEFCQSKATGEEITESEVLLGIDLLCGNGCDDLDLSLLSWLQNLPSSVFSCAFEQKMLNIHVDKLLKPTKAAYADLLTPLISKLSPYPSSPMRRPQSADAYMTRSLNPALDGLTCGLTSHDKRISDLGNKTSPMSHSFANFHYPGVQNLSRSLLLENTECHSIYEESPERSDTPVETQQPVSIEPMCQGSGLEKEPANGAQNPVPAKQQEKNELRDSTEQFQEYYRQRLRYQQHLEQKEQQRQIYQQMLLEGGVNQEDGPDQQQNLTEQFLNRSIQKLGELNIGMDSLGNEVPVLNQQCLGSKNSGSNNSSVTSFSSPPQDSSQRLTHDTSNIHTSTPRNPGSTNHIPFLEESPCGSQNSSEHSVVKPSPGDSSGSLSRSKGEEDDKSKKQFVCINTLEDTQAVRAVAFHPSGSLYAVGSNSKTLRVCAYPEKLDTSAHDGPKQPVVRFKRNKHHKGSIYCVAWSPCGQLLATGSNDKYVKVLPFNAETCNATGPDLEFSMHDGTIRDLAFMEGPESGGAILISAGAGDCNIYTTDCQRGQGLHALSGHTGHILALYTWSGWMIASGSQDKTVRFWDLRVPSCVRVVGTTFHGTGSAVASVAVDPSGRLLATGQEDSSCMLYDIRGGRMVQSYHPHSSDVRSVRFSPGAHYLLTGSYDMKIKVTDLQGDLTKQLPLMVVGEHKDKVIQCRWHTQDLSFLSSSADRTVTLWTYSG", "length": 928 }, "evidence": [ { "id": "A0A8V0YL57", "url": "https://omabrowser.org/oma/group/A0A8V0YL57/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O94967-1", "protein_name": "WD repeat-containing protein 47", "gene_name": "WDR47", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTAEETVNVKEVEIIKLILDFLNSKKLHISMLALEKESGVINGLFSDDMLFLRQLILDGQWDEVLQFIQPLECMEKFDKKRFRYIILKQKFLEALCVNNAMSAEDEPQHLEFTMQEAVQCLHALEEYCPSKDDYSKLCLLLTLPRLTNHAEFKDWNPSTARVHCFEEACVMVAEFIPADRKLSEAGFKASNNRLFQLVMKGLLYECCVEFCQSKATGEEITESEVLLGIDLLCGNGCDDLDLSLLSWLQNLPSSVFSCAFEQKMLNIHVDKLLKPTKAAYADLLTPLISKLSPYPSSPMRRPQSADAYMTRSLNPALDGLTCGLTSHDKRISDLGNKTSPMSHSFANFHYPGVQNLSRSLMLENTECHSIYEESPERDTPVDAQRPIGSEILGQSSVSEKEPANGAQNPGPAKQEKNELRDSTEQFQEYYRQRLRYQQHLEQKEQQRQIYQQMLLEGGVNQEDGPDQQQNLTEQFLNRSIQKLGELNIGMDGLGNEVSALNQQCNGSKGNGSNGSSVTSFTTPPQDSSQRLTHDASNIHTSTPRNPGSTNHIPFLEESPCGSQISSEHSVIKPPLGDSPGSLSRSKGEEDDKSKKQFVCINILEDTQAVRAVAFHPAGGLYAVGSNSKTLRVCAYPDVIDPSAHETPKQPVVRFKRNKHHKGSIYCVAWSPCGQLLATGSNDKYVKVLPFNAETCNATGPDLEFSMHDGTIRDLAFMEGPESGGAILISAGAGDCNIYTTDCQRGQGLHALSGHTGHILALYTWSGWMIASGSQDKTVRFWDLRVPSCVRVVGTTFHGTGSAVASVAVDPSGRLLATGQEDSSCMLYDIRGGRMVQSYHPHSSDVRSVRFSPGAHYLLTGSYDMKIKVTDLQGDLTKQLPIMVVGEHKDKVIQCRWHTQDLSFLSSSADRTVTLWTYNG", "length": 919 }, "evidence": [ { "id": "A0A8V0YL57", "url": "https://omabrowser.org/oma/group/A0A8V0YL57/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8CGF6-1", "protein_name": "WD repeat-containing protein 47", "gene_name": "Wdr47", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTAEETVNVKEVEIIKLILDFLNSKKLHISMLALEKESGVINGLFSDDMLFLRQLILDGQWDEVLQFIQPLECMEKFDKKRFRYIILKQKFLEALCVNNAMSAEDEPQHLEFTMQEAVQCLHALEEYCPSKDDYSKLCLLLTLPRLTNHAEFKDWNPSTARVHCFEEVCVMVAEFIPADRKLSEAGFKASNNRLFQLVMKGLLYECCVEFCQSKATGEEITESEVLLGIDLLCGNGCDDLDLSLLSWLQNLPSSVFSCAFEQKMLNIHVDKLLKPTKAAYADLLTPLISKLSPYPSSPMRRPQSADAYMTRSLNPALDGLTCGLTSHDKRISDLGNKTSPMSHSFANFHYPGVQNLSRSLMLENTECHSIYEESPERSDTPVEAQQPVSSEAMCQGSGLEKEPANGAQNPVPAKQEKNELRDSTEQFQEYYRQRLRYQQHLEQKEQQRQMYQQMLLEGGVNQEDGPDQQQNLTEQFLNRSIQKLGELNIGMDSLGNEVPVLNQQCSGSKNNGSNNSSVTSFSTPPQDSSQRLIHDTANIHTSTPRNPGSTNHIPFHEDSPCGSQNSSEHSVIKPSPGDSSGNLSRSKGEEDDKSKKQFVCINTLEDTQAVRAVAFHPSGSLYAVGSNSKTLRVCAYPEKMDASAHDNPKQPVVRFKRNKHHKGSIYCVAWSPCGQLLATGSNDKYVKVLPFNAETCNATGPDLEFSMHDGTIRDLAFMEGPESGGAILISAGAGDCNIYTTDCQRGQGLHALSGHTGHILALYTWSGWMIASGSQDKTVRFWDLRVPSCVRVVGTTFHGTGSAVASVAVDPSGRLLATGQEDSSCMLYDIRGGRMVQSYHPHSSDVRSVRFSPGAHYLLTGSYDMKIKVTDLQGDLTKQLPLMVVGEHKDKVIQCRWHTQDLSFLSSSADRTVTLWTYSG", "length": 920 }, "evidence": [ { "id": "A0A8V0YL57", "url": "https://omabrowser.org/oma/group/A0A8V0YL57/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YL57", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL57" } ], "pmid": "" }, { "name": "microtubule", "id": "GO:0005874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005874", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YL57", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL57" } ], "pmid": "" }, { "name": "dendrite", "id": "GO:0030425", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030425", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YL57", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL57" } ], "pmid": "" }, { "name": "growth cone", "id": "GO:0030426", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030426", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YL57", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL57" } ], "pmid": "" }, { "name": "cell body", "id": "GO:0044297", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044297", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YL57", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL57" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "protein-containing complex binding", "id": "GO:0044877", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044877", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YL57", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL57" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 355, "end_pos": 357, "annotation": "n_glycosylation_sequon" }, { "start_pos": 470, "end_pos": 472, "annotation": "n_glycosylation_sequon" }, { "start_pos": 477, "end_pos": 479, "annotation": "n_glycosylation_sequon" }, { "start_pos": 505, "end_pos": 507, "annotation": "n_glycosylation_sequon" }, { "start_pos": 510, "end_pos": 512, "annotation": "n_glycosylation_sequon" }, { "start_pos": 518, "end_pos": 520, "annotation": "n_glycosylation_sequon" }, { "start_pos": 535, "end_pos": 537, "annotation": "n_glycosylation_sequon" }, { "start_pos": 578, "end_pos": 580, "annotation": "n_glycosylation_sequon" }, { "start_pos": 693, "end_pos": 695, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YL57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL57" }, { "id": "PS50897", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50897" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CTLH", "eco_id": "ECO_0000259", "start_pos": 45, "end_pos": 102, "start_aa": "Phe", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 355, "end_pos": 357 }, { "start_pos": 470, "end_pos": 472 }, { "start_pos": 477, "end_pos": 479 }, { "start_pos": 505, "end_pos": 507 }, { "start_pos": 510, "end_pos": 512 }, { "start_pos": 518, "end_pos": 520 }, { "start_pos": 535, "end_pos": 537 }, { "start_pos": 578, "end_pos": 580 }, { "start_pos": 693, "end_pos": 695 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YKN1-1", "uniprot_ac": "A0A8V0YKN1", "uniprot_id": "A0A8V0YKN1_CHICK", "mass": { "chemical_mass": 166315.0, "monoisotopic_mass": 166315.0 }, "refseq": { "ac": "XP_004937680", "name": "early endosome antigen 1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004937680" }, "gene_names": [ { "name": "EEA1", "type": "recommended", "evidence": [ { "id": "A0A8V0YKN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKN1" } ] }, { "name": "EEA1", "type": "synonym", "evidence": [ { "id": "XP_004937680", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004937680" } ] } ], "protein_names": [ { "name": "Early endosome antigen 1", "type": "synonym", "evidence": [ { "id": "A0A8V0YKN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKN1/entry#names_and_taxonomy" } ] }, { "name": "early endosome antigen 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_004937680", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004937680" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_004937680.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004937680", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004937680" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKN1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKN1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "EEA1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKN1", "locus": { "chromosome": "1", "start_pos": 44675106, "end_pos": 44741733, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013440", "url": "https://www.ensembl.org/id/ENSGALG00010013440" } ] } } ], "crossref": [ { "id": "cd15730", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15730", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "417896", "url": "https://www.ncbi.nlm.nih.gov/gene/417896", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000306", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000306", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011011", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011011", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017455", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017455", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:417896", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417896", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "FIAVYQH", "url": "https://omabrowser.org/oma/group/FIAVYQH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YE87", "url": "https://www.orthodb.org/?gene=A0A8V0YE87", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YE97", "url": "https://www.orthodb.org/?gene=A0A8V0YE97", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YKL5", "url": "https://www.orthodb.org/?gene=A0A8V0YKL5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YKN1", "url": "https://www.orthodb.org/?gene=A0A8V0YKN1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YKN6", "url": "https://www.orthodb.org/?gene=A0A8V0YKN6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YSG1", "url": "https://www.orthodb.org/?gene=A0A8V0YSG1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YSG7", "url": "https://www.orthodb.org/?gene=A0A8V0YSG7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23164", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23164", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23164:SF30", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23164:SF30", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01363", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01363", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_004937680", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004937680", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YE87", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE87", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YE87-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE87-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YE97", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE97", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YE97-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE97-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YKL5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKL5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YKL5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKL5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YKN1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKN1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YKN1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKN1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YKN6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKN6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YKN6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKN6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YSG1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSG1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YSG1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSG1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YSG7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSG7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YSG7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSG7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MFRRILQRTPGRVGSQSSDSDLSAAPGNAVDVNNEGSSEGFICPLCMKVCVTPTDLSEHYQNEHTGTEGRQELRDLPAVTGFICPLCMKSHGSAEELFKHYEAVHNSGIDSTRGGEGHLSPERDEVSLLRQEVQDLQASLKEERWYSEELKKELEKLQGQRQQDSKSDGLTTSTSTESLERQLEEIQVENFNIKQMKDLFEQKAAQLATEIVDLKAKYDEEISLREGAEQKMTNLTQELLKERSTIEDLKTELLQRPGVEDVAVLKKELVQVQTLMDKMTLERERESEKLKDECKHLQAEQANSEATINQLRAELAKGPQEVAVYVQEQQKLQSLVKELEQKNQNLTEKLLKKEQEYSQLEEKHNEISVSKKNVQASFHQKDLDCQQLQAKLSASEASVQRLQTELGEKGEASQKLKEELSEVETKYQHLKAECKQLQQQREEKEQHGLQLQSELSQLHSKLLETERQLGEAHGRLKEQRQLSSEKLMDREQQVADLQLKLSRAEEQLKEKVANSTELQHQLDKAKQQHQEQQTLQQNTTSKLREAQNDLEQVLRQIGDKDQKIQNLEALLQKSKENISLLEKEREDLYAKIQAGEGETAVLNQLQEKNHALQIQVTQLTEKLKNQSESHKQAQENLHEQVQEQKAHLRAAQDRVLSLEANITELSSQLNESKEKVSQLDVQVKAKTELLLSAEASKAAQRADLQNHLDTAQHALQDKQQELNKVSVQLDQVTAKLNDKQEYCAQLEANLKDYKEQHLYLEQKTEELEGQLKKLEADVLDAKASKEQALQELQQQRQQSTELDLRIAELSKQLEAEREAMSSAKSDLQKKSEALEQAKQQISKQEEETASLKKNLEKSSQDTSKQLKDLDCKMQAATSELQQVKLEKDTLLKDLTSTKEKLSKSSESFKKRKEELEKEIEKGKAAVAEMEKSYQEVKQQLQVQTESVAKERNELKNSLEKKEGISKQLSIELDSTRAQVLEIQGLLKEKENSEQHLQGKLREMKESFEQKKKHSETLQAELKTALLEKAELENKLQQQTILSAQELKAEKGKLADLQKTHEKNKENMEKLQLDLYGKESELLATRQDLKSTEEKLALAQEELVSSRNRIASSNQQIQELKKAKSTLEQDASKKEQQLGEKTKMLQDLQNERILKEKDLANEKCKTTELQEIRSRLEKESAKLSEELRICKQEFEKEVANLKDAKQLLIQQKLELQGKIDNMNSTLEQEKKNQQAVKDQLKKREEELKKECAEIEAKLQSEVKEKEEENRKHEEKETKLTMQVTALNENLATMKKEWQSSQRRVSELEKQTDDLRGDIAVLEATVQNNQDERRALLERCIKSEGEIEKLQSKLVEMKKKLDNTTAAMQELGRENQSLQIKHTQALNRKWAEDNEVQNCMACGKGFSVTVRRHHCRQCGNIFCAECSAKNALTPSSKKPVRVCDTCFNDLQG", "length": 1450, "header": "tr|A0A8V0YKN1-1|A0A8V0YKN1_CHICK Isoform 1 of Early endosome antigen 1 OS=Gallus gallus OX=9031 GN=EEA1 PE=1 SV=1 CANONICAL=A0A8V0YKN1-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YE87-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKN1/entry#A0A8V0YE87-1", "sequence": { "sequence": "MSTRGQKEDRSFVTFQLLLDEVSLLRQEVQDLQASLKEERWYSEELKKELEKLQGQRQQDSKSDGLTTSTSTESLERQLEEIQVENFNIKQMKDLFEQKAAQLATEIVDLKAKYDEEISLREGAEQKMTNLTQELLKERSTIEDLKTELLQRPGVEDVAVLKKELVQVQTLMDKMTLERERESEKLKDECKHLQAEQANSEATINQLRAELAKGPQEVAVYVQEQQKLQSLVKELEQKNQNLTEKLLKKEQEYSQLEEKHNEISVSKKNVQASFHQKDLDCQQLQAKLSASEASVQRLQTELGEKGEASQKLKEELSEVETKYQHLKAECKQLQQQREEKEQHGLQLQSELSQLHSKLLETERQLGEAHGRLKEQRQLSSEKLMDREQQVADLQLKLSRAEEQLKEKVANSTELQHQLDKAKQQHQEQQTLQQNTTSKLREAQNDLEQVLRQIGDKDQKIQNLEALLQKSKENISLLEKEREDLYAKIQAGEGETAVLNQLQEKNHALQIQVTQLTEKLKNQSESHKQAQENLHEQVQEQKAHLRAAQDRVLSLEANITELSSQLNESKEKVSQLDVQVKAKTELLLSAEASKAAQRADLQNHLDTAQHALQDKQQELNKVSVQLDQVTAKLNDKQEYCAQLEANLKDYKEQHLYLEQKTEELEGQLKKLEADVLDAKASKEQALQELQQQRQQSTELDLRIAELSKQLEAEREAMSSAKSDLQKKSEALEQAKQQISKQEEETASLKKNLEKSSQDTSKQLKDLDCKMQAATSELQQVKLEKDTLLKDLTSTKEKLSKSSESFKKRKEELEKEIEKGKAAVAEMEKSYQEVKQQLQVQTESVAKERNELKNSLEKKEGISKQLSIELDSTRAQVLEIQGLLKEKENSEQHLQGKLREMKESFEQKKKHSETLQAELKTALLEKAELENKLQQQTILSAQELKAEKGKLADLQKTHEKNKENMEKLQLDLYGKESELLATRQDLKSTEEKLALAQEELVSSRNRIASSNQQIQELKKAKSTLEQDASKKEQQLGEKTKMLQDLQNERILKEKDLANEKCKTTELQEIRSRLEKESAKLSEELRICKQEFEKEVANLKDAKQLLIQQKLELQGKIDNMNSTLEQEKKNQQAVKDQLKKREEELKKECAEIEAKLQSEVKEKEEENRKHEEKETKLTMQVTALNENLATMKKEWQSSQRRVSELEKQTDDLRGDIAVLEATVQNNQDERRALLERCIKSEGEIEKLQSKLVEMKKKLDNTTAAMQELGRENQSLQIKHTQALNRKWAEDNEVQNCMACGKGFSVTVRRHHCRQCGNIFCAECSAKNALTPSSKKPVRVCDTCFNDLQG", "length": 1346, "header": "tr|A0A8V0YE87-1|A0A8V0YKN1_CHICK Computationally mapped isoform of Early endosome antigen 1 OS=Gallus gallus OX=9031 GN=EEA1 PE=1 SV=1 CANONICAL=A0A8V0YKN1-1" }, "locus": { "chromosome": "1", "start_pos": 44732053, "end_pos": 44675387, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032357.1", "url": "https://www.ensembl.org/id/ENSGALT00010032357.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019133.1", "url": "https://www.ensembl.org/id/ENSGALP00010019133.1" } ] } }, { "isoform_ac": "A0A8V0YE97-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKN1/entry#A0A8V0YE97-1", "sequence": { "sequence": "MFRRILQRTPGRVGSQSSDSDLSAAPGNAVDVNNEGSSEGFICPLCMKVCVTPTDLSEHYQNEHTGTEGRQELRDLPAVTEERWYSEELKKELEKLQGQRQQDSKSDGLTTSTSTESLERQLEEIQVENFNIKQMKDLFEQKAAQLATEIVDLKAKYDEEISLREGAEQKMTNLTQELLKERSTIEDLKTELLQRPGVEDVAVLKKELVQVQTLMDKMTLERERESEKLKDECKHLQAEQANSEATINQLRAELAKGPQEVAVYVQEQQKLQSLVKELEQKNQNLTEKLLKKEQEYSQLEEKHNEISVSKKNVQASFHQKDLDCQQLQAKLSASEASVQRLQTELGEKGEASQKLKEELSEVETKYQHLKAECKQLQQQREEKEQHGLQLQSELSQLHSKLLETERQLGEAHGRLKEQRQLSSEKLMDREQQVADLQLKLSRAEEQLKEKVANSTELQHQLDKAKQQHQEQQTLQQNTTSKLREAQNDLEQVLRQIGDKDQKIQNLEALLQKSKENISLLEKEREDLYAKIQAGEGETAVLNQLQEKNHALQIQVTQLTEKLKNQSESHKQAQENLHEQVQEQKAHLRAAQDRVLSLEANITELSSQLNESKEKVSQLDVQVKAKTELLLSAEASKAAQRADLQNHLDTAQHALQDKQQELNKVSVQLDQVTAKLNDKQEYCAQLEANLKDYKEQHLYLEQKTEELEGQLKKLEADVLDAKASKEQALQELQQQRQQSTELDLRIAELSKQLEAEREAMSSAKSDLQKKSEALEQAKQQISKQEEETASLKKNLEKSSQDTSKQLKDLDCKMQAATSELQQVKLEKDTLLKDLTSTKEKLSKSSESFKKRKEELEKEIEKGKAAVAEMEKSYQEVKQQLQVQTESVAKERNELKNSLEKKEGISKQLSIELDSTRAQVLEIQGLLKEKENSEQHLQGKLREMKESFEQKKKHSETLQAELKTALLEKAELENKLQQQTILSAQELKAEKGKLADLQKTHEKNKENMEKLQLDLYGKESELLATRQDLKSTEEKLALAQEELVSSRNRIASSNQQIQELKKAKSTLEQDASKKEQQLGEKTKMLQDLQNERILKEKDLANEKCKTTELQEIRSRLEKESAKLSEELRICKQEFEKEVANLKDAKQLLIQQKLELQGKIDNMNSTLEQEKKNQQAVKDQLKKREEELKKECAEIEAKLQSEVKEKEEENRKHEEKETKLTMQVTALNENLATMKKEWQSSQRRVSELEKQTDDLRGDIAVLEATVQNNQDERRALLERCIKSEGEIEKLQSKLVEMKKKLDNTTAAMQELGRENQSLQIKHTQALNRKWAEDNEVQNCMACGKGFSVTVRRHHCRQCGNIFCAECSAKNALTPSSKKPVRVCDTCFNDLQG", "length": 1389, "header": "tr|A0A8V0YE97-1|A0A8V0YKN1_CHICK Computationally mapped isoform of Early endosome antigen 1 OS=Gallus gallus OX=9031 GN=EEA1 PE=1 SV=1 CANONICAL=A0A8V0YKN1-1" }, "locus": { "chromosome": "1", "start_pos": 44740874, "end_pos": 44675387, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032371.1", "url": "https://www.ensembl.org/id/ENSGALT00010032371.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019143.1", "url": "https://www.ensembl.org/id/ENSGALP00010019143.1" } ] } }, { "isoform_ac": "A0A8V0YKL5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKN1/entry#A0A8V0YKL5-1", "sequence": { "sequence": "MKKCSCILAVTEGSRFWEEVVHSLCSCQTPGRVGSQSSDSDLSAAPGNAVDVNNEGSSEGFICPLCMKSHGSAEELFKHYEAVHNSGIDSTRGGEGHLSPERDEVSLLRQEVQDLQASLKEERWYSEELKKELEKLQGQRQQDSKSDGLTTSTSTESLERQLEEIQVENFNIKQMKDLFEQKAAQLATEIVDLKAKYDEEISLREGAEQKMTNLTQELLKERSTIEDLKTELLQRPGVEDVAVLKKELVQVQTLMDKMTLERERESEKLKDECKHLQAEQANSEATINQLRAELAKGPQEVAVYVQEQQKLQSLVKELEQKNQNLTEKLLKKEQEYSQLEEKHNEISVSKKNVQASFHQKDLDCQQLQAKLSASEASVQRLQTELGEKGEASQKLKEELSEVETKYQHLKAECKQLQQQREEKEQHGLQLQSELSQLHSKLLETERQLGEAHGRLKEQRQLSSEKLMDREQQVADLQLKLSRAEEQLKEKVANSTELQHQLDKAKQQHQEQQTLQQNTTSKLREAQNDLEQVLRQIGDKDQKIQNLEALLQKSKENISLLEKEREDLYAKIQAGEGETAVLNQLQEKNHALQIQVTQLTEKLKNQSESHKQAQENLHEQVQEQKAHLRAAQDRVLSLEANITELSSQLNESKEKVSQLDVQVKAKTELLLSAEASKAAQRADLQNHLDTAQHALQDKQQELNKVSVQLDQVTAKLNDKQEYCAQLEANLKDYKEQHLYLEQKTEELEGQLKKLEADVLDAKASKEQALQELQQQRQQSTELDLRIAELSKQLEAEREAMSSAKSDLQKKSEALEQAKQQISKQEEETASLKKNLEKSSQDTSKQLKDLDCKMQAATSELQQVKLEKDTLLKDLTSTKEKLSKSSESFKKRKEELEKEIEKGKAAVAEMEKSYQEVKQQLQVQTESVAKERNELKNSLEKKEGISKQLSIELDSTRAQVLEIQGLLKEKENSEQHLQGKLREMKESFEQKKKHSETLQAELKTALLEKAELENKLQQQTILSAQELKAEKGKLADLQKTHEKNKENMEKLQLDLYGKESELLATRQDLKSTEEKLALAQEELVSSRNRIASSNQQIQELKKAKSTLEQDASKKEQQLGEKTKMLQDLQNERILKEKDLANEKCKTTELQEIRSRLEKESAKLSEELRICKQEFEKEVANLKDAKQLLIQQKLELQGKIDNMNSTLEQEKKNQQAVKDQLKKREEELKKECAEIEAKLQSEVKEKEEENRKHEEKETKLTMQVTALNENLATMKKEWQSSQRRVSELEKQTDDLRGDIAVLEATVQNNQDERRALLERCIKSEGEIEKLQSKLVEMKKKLDNTTAAMQELGRENQSLQIKHTQALNRKWAEDNEVQNCMACGKGFSVTVRRHHCRQCGNIFCAECSAKNALTPSSKKPVRVCDTCFNDLQG", "length": 1429, "header": "tr|A0A8V0YKL5-1|A0A8V0YKL5_CHICK Computationally mapped isoform of Early endosome antigen 1 OS=Gallus gallus OX=9031 GN=EEA1 PE=1 SV=1 CANONICAL=A0A8V0YKN1-1" }, "locus": { "chromosome": "1", "start_pos": 44736939, "end_pos": 44675387, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032347.1", "url": "https://www.ensembl.org/id/ENSGALT00010032347.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019125.1", "url": "https://www.ensembl.org/id/ENSGALP00010019125.1" } ] } }, { "isoform_ac": "A0A8V0YKN1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKN1/entry#A0A8V0YKN1-1", "sequence": { "sequence": "MFRRILQRTPGRVGSQSSDSDLSAAPGNAVDVNNEGSSEGFICPLCMKVCVTPTDLSEHYQNEHTGTEGRQELRDLPAVTGFICPLCMKSHGSAEELFKHYEAVHNSGIDSTRGGEGHLSPERDEVSLLRQEVQDLQASLKEERWYSEELKKELEKLQGQRQQDSKSDGLTTSTSTESLERQLEEIQVENFNIKQMKDLFEQKAAQLATEIVDLKAKYDEEISLREGAEQKMTNLTQELLKERSTIEDLKTELLQRPGVEDVAVLKKELVQVQTLMDKMTLERERESEKLKDECKHLQAEQANSEATINQLRAELAKGPQEVAVYVQEQQKLQSLVKELEQKNQNLTEKLLKKEQEYSQLEEKHNEISVSKKNVQASFHQKDLDCQQLQAKLSASEASVQRLQTELGEKGEASQKLKEELSEVETKYQHLKAECKQLQQQREEKEQHGLQLQSELSQLHSKLLETERQLGEAHGRLKEQRQLSSEKLMDREQQVADLQLKLSRAEEQLKEKVANSTELQHQLDKAKQQHQEQQTLQQNTTSKLREAQNDLEQVLRQIGDKDQKIQNLEALLQKSKENISLLEKEREDLYAKIQAGEGETAVLNQLQEKNHALQIQVTQLTEKLKNQSESHKQAQENLHEQVQEQKAHLRAAQDRVLSLEANITELSSQLNESKEKVSQLDVQVKAKTELLLSAEASKAAQRADLQNHLDTAQHALQDKQQELNKVSVQLDQVTAKLNDKQEYCAQLEANLKDYKEQHLYLEQKTEELEGQLKKLEADVLDAKASKEQALQELQQQRQQSTELDLRIAELSKQLEAEREAMSSAKSDLQKKSEALEQAKQQISKQEEETASLKKNLEKSSQDTSKQLKDLDCKMQAATSELQQVKLEKDTLLKDLTSTKEKLSKSSESFKKRKEELEKEIEKGKAAVAEMEKSYQEVKQQLQVQTESVAKERNELKNSLEKKEGISKQLSIELDSTRAQVLEIQGLLKEKENSEQHLQGKLREMKESFEQKKKHSETLQAELKTALLEKAELENKLQQQTILSAQELKAEKGKLADLQKTHEKNKENMEKLQLDLYGKESELLATRQDLKSTEEKLALAQEELVSSRNRIASSNQQIQELKKAKSTLEQDASKKEQQLGEKTKMLQDLQNERILKEKDLANEKCKTTELQEIRSRLEKESAKLSEELRICKQEFEKEVANLKDAKQLLIQQKLELQGKIDNMNSTLEQEKKNQQAVKDQLKKREEELKKECAEIEAKLQSEVKEKEEENRKHEEKETKLTMQVTALNENLATMKKEWQSSQRRVSELEKQTDDLRGDIAVLEATVQNNQDERRALLERCIKSEGEIEKLQSKLVEMKKKLDNTTAAMQELGRENQSLQIKHTQALNRKWAEDNEVQNCMACGKGFSVTVRRHHCRQCGNIFCAECSAKNALTPSSKKPVRVCDTCFNDLQG", "length": 1450, "header": "tr|A0A8V0YKN1-1|A0A8V0YKN1_CHICK Isoform 1 of Early endosome antigen 1 OS=Gallus gallus OX=9031 GN=EEA1 PE=1 SV=1 CANONICAL=A0A8V0YKN1-1" }, "locus": { "chromosome": "1", "start_pos": 44740874, "end_pos": 44675387, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032368.1", "url": "https://www.ensembl.org/id/ENSGALT00010032368.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019140.1", "url": "https://www.ensembl.org/id/ENSGALP00010019140.1" } ] } }, { "isoform_ac": "A0A8V0YKN6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKN1/entry#A0A8V0YKN6-1", "sequence": { "sequence": "MLEAVRCSSQKPHRRFASAPVKHKPFLDRTARFGAILCLTTPGRVGSQSSDSDLSAAPGNAVDVNNEGSSEGFICPLCMKSHGSAEELFKHYEAVHNSGIDSTRGGEGHLSPERDEVSLLRQEVQDLQASLKEERWYSEELKKELEKLQGQRQQDSKSDGLTTSTSTESLERQLEEIQVENFNIKQMKDLFEQKAAQLATEIVDLKAKYDEEISLREGAEQKMTNLTQELLKERSTIEDLKTELLQRPGVEDVAVLKKELVQVQTLMDKMTLERERESEKLKDECKHLQAEQANSEATINQLRAELAKGPQEVAVYVQEQQKLQSLVKELEQKNQNLTEKLLKKEQEYSQLEEKHNEISVSKKNVQASFHQKDLDCQQLQAKLSASEASVQRLQTELGEKGEASQKLKEELSEVETKYQHLKAECKQLQQQREEKEQHGLQLQSELSQLHSKLLETERQLGEAHGRLKEQRQLSSEKLMDREQQVADLQLKLSRAEEQLKEKVANSTELQHQLDKAKQQHQEQQTLQQNTTSKLREAQNDLEQVLRQIGDKDQKIQNLEALLQKSKENISLLEKEREDLYAKIQAGEGETAVLNQLQEKNHALQIQVTQLTEKLKNQSESHKQAQENLHEQVQEQKAHLRAAQDRVLSLEANITELSSQLNESKEKVSQLDVQVKAKTELLLSAEASKAAQRADLQNHLDTAQHALQDKQQELNKVSVQLDQVTAKLNDKQEYCAQLEANLKDYKEQHLYLEQKTEELEGQLKKLEADVLDAKASKEQALQELQQQRQQSTELDLRIAELSKQLEAEREAMSSAKSDLQKKSEALEQAKQQISKQEEETASLKKNLEKSSQDTSKQLKDLDCKMQAATSELQQVKLEKDTLLKDLTSTKEKLSKSSESFKKRKEELEKEIEKGKAAVAEMEKSYQEVKQQLQVQTESVAKERNELKNSLEKKEGISKQLSIELDSTRAQVLEIQGLLKEKENSEQHLQGKLREMKESFEQKKKHSETLQAELKTALLEKAELENKLQQQTILSAQELKAEKGKLADLQKTHEKNKENMEKLQLDLYGKESELLATRQDLKSTEEKLALAQEELVSSRNRIASSNQQIQELKKAKSTLEQDASKKEQQLGEKTKMLQDLQNERILKEKDLANEKCKTTELQEIRSRLEKESAKLSEELRICKQEFEKEVANLKDAKQLLIQQKLELQGKIDNMNSTLEQEKKNQQAVKDQLKKREEELKKECAEIEAKLQSEVKEKEEENRKHEEKETKLTMQVTALNENLATMKKEWQSSQRRVSELEKQTDDLRGDIAVLEATVQNNQDERRALLERCIKSEGEIEKLQSKLVEMKKKLDNTTAAMQELGRENQSLQIKHTQALNRKWAEDNEVQNCMACGKGFSVTVRRHHCRQCGNIFCAECSAKNALTPSSKKPVRVCDTCFNDLQG", "length": 1441, "header": "tr|A0A8V0YKN6-1|A0A8V0YKN6_CHICK Computationally mapped isoform of Early endosome antigen 1 OS=Gallus gallus OX=9031 GN=EEA1 PE=1 SV=1 CANONICAL=A0A8V0YKN1-1" }, "locus": { "chromosome": "1", "start_pos": 44741534, "end_pos": 44675387, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032375.1", "url": "https://www.ensembl.org/id/ENSGALT00010032375.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019145.1", "url": "https://www.ensembl.org/id/ENSGALP00010019145.1" } ] } }, { "isoform_ac": "A0A8V0YSG1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKN1/entry#A0A8V0YSG1-1", "sequence": { "sequence": "MRAPLRDEVSLLRQEVQDLQASLKEERWYSEELKKELEKLQGQRQQDSKSDGLTTSTSTESLERQLEEIQVENFNIKQMKDLFEQKAAQLATEIVDLKAKYDEEISLREGAEQKMTNLTQELLKERSTIEDLKTELLQRPGVEDVAVLKKELVQVQTLMDKMTLERERESEKLKDECKHLQAEQANSEATINQLRAELAKGPQEVAVYVQEQQKLQSLVKELEQKNQNLTEKLLKKEQEYSQLEEKHNEISVSKKNVQASFHQKDLDCQQLQAKLSASEASVQRLQTELGEKGEASQKLKEELSEVETKYQHLKAECKQLQQQREEKEQHGLQLQSELSQLHSKLLETERQLGEAHGRLKEQRQLSSEKLMDREQQVADLQLKLSRAEEQLKEKVANSTELQHQLDKAKQQHQEQQTLQQNTTSKLREAQNDLEQVLRQIGDKDQKIQNLEALLQKSKENISLLEKEREDLYAKIQAGEGETAVLNQLQEKNHALQIQVTQLTEKLKNQSESHKQAQENLHEQVQEQKAHLRAAQDRVLSLEANITELSSQLNESKEKVSQLDVQVKAKTELLLSAEASKAAQRADLQNHLDTAQHALQDKQQELNKVSVQLDQVTAKLNDKQEYCAQLEANLKDYKEQHLYLEQKTEELEGQLKKLEADVLDAKASKEQALQELQQQRQQSTELDLRIAELSKQLEAEREAMSSAKSDLQKKSEALEQAKQQISKQEEETASLKKNLEKSSQDTSKQLKDLDCKMQAATSELQQVKLEKDTLLKDLTSTKEKLSKSSESFKKRKEELEKEIEKGKAAVAEMEKSYQEVKQQLQVQTESVAKERNELKNSLEKKEGISKQLSIELDSTRAQVLEIQGLLKEKENSEQHLQGKLREMKESFEQKKKHSETLQAELKTALLEKAELENKLQQQTILSAQELKAEKGKLADLQKTHEKNKENMEKLQLDLYGKESELLATRQDLKSTEEKLALAQEELVSSRNRIASSNQQIQELKKAKSTLEQDASKKEQQLGEKTKMLQDLQNERILKEKDLANEKCKTTELQEIRSRLEKESAKLSEELRICKQEFEKEVANLKDAKQLLIQQKLELQGKIDNMNSTLEQEKKNQQAVKDQLKKREEELKKECAEIEAKLQSEVKEKEEENRKHEEKETKLTMQVTALNENLATMKKEWQSSQRRVSELEKQTDDLRGDIAVLEATVQNNQDERRALLERCIKSEGEIEKLQSKLVEMKKKLDNTTAAMQELGRENQSLQIKHTQALNRKWAEDNEVQNCMACGKGFSVTVRRHHCRQCGNIFCAECSAKNALTPSSKKPVRVCDTCFNDLQG", "length": 1333, "header": "tr|A0A8V0YSG1-1|A0A8V0YSG1_CHICK Computationally mapped isoform of Early endosome antigen 1 OS=Gallus gallus OX=9031 GN=EEA1 PE=1 SV=1 CANONICAL=A0A8V0YKN1-1" }, "locus": { "chromosome": "1", "start_pos": 44734903, "end_pos": 44675387, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032352.1", "url": "https://www.ensembl.org/id/ENSGALT00010032352.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019129.1", "url": "https://www.ensembl.org/id/ENSGALP00010019129.1" } ] } }, { "isoform_ac": "A0A8V0YSG7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKN1/entry#A0A8V0YSG7-1", "sequence": { "sequence": "MFRRILQRTPGRVGSQSSDSDLSAAPGNAVDVNNEGSSEGFICPLCMKSHGSAEELFKHYEAVHNSGIDSTRGGEGHLSPERDEVSLLRQEVQDLQASLKEERWYSEELKKELEKLQGQRQQDSKSDGLTTSTSTESLERQLEEIQVENFNIKQMKDLFEQKAAQLATEIVDLKAKYDEEISLREGAEQKMTNLTQELLKERSTIEDLKTELLQRPGVEDVAVLKKELVQVQTLMDKMTLERERESEKLKDECKHLQAEQANSETLKCEATINQLRAELAKGPQEVAVYVQEQQKLQSLVKELEQKNQNLTEKLLKKEQEYSQLEEKHNEISVSKKNVQASFHQKDLDCQQLQAKLSASEASVQRLQTELGEKGEASQKLKEELSEVETKYQHLKAECKQLQQQREEKEQHGLQLQSELSQLHSKLLETERQLGEAHGRLKEQRQLSSEKLMDREQQVADLQLKLSRAEEQLKEKVANSTELQHQLDKAKQQHQEQQTLQQNTTSKLREAQNDLEQVLRQIGDKDQKIQNLEALLQKSKENISLLEKEREDLYAKIQAGEGETAVLNQLQEKNHALQIQVTQLTEKLKNQSESHKQAQENLHEQVQEQKAHLRAAQDRVLSLEANITELSSQLNESKEKVSQLDVQVKAKTELLLSAEASKAAQRADLQNHLDTAQHALQDKQQELNKVSVQLDQVTAKLNDKQEYCAQLEANLKDYKEQHLYLEQKTEELEGQLKKLEADVLDAKASKEQALQELQQQRQQSTELDLRIAELSKQLEAEREAMSSAKSDLQKKSEALEQAKQQISKQEEETASLKKNLEKSSQDTSKQLKDLDCKMQAATSELQQVKLEKDTLLKDLTSTKEKLSKSSESFKKRKEELEKEIEKGKAAVAEMEKSYQEVKQQLQVQTESVAKERNELKNSLEKKEGISKQLSIELDSTRAQVLEIQGLLKEKENSEQHLQGKLREMKESFEQKKKHSETLQAELKTALLEKAELENKLQQQTILSAQELKAEKGKLADLQKTHEKNKENMEKLQLDLYGKESELLATRQDLKSTEEKLALAQEELVSSRNRIASSNQQIQELKKAKSTLEQDASKKEQQLGEKTKMLQDLQNERILKEKDLANEKCKTTELQEIRSRLEKESAKLSEELRICKQEFEKEVANLKDAKQLLIQQKLELQGKIDNMNSTLEQEKKNQQAVKDQLKKREEELKKECAEIEAKLQSEVKEKEEENRKHEEKETKLTMQVTALNENLATMKKEWQSSQRRVSELEKQTDDLRGDIAVLEATVQNNQDERRALLERCIKSEGEIEKLQSKLVEMKKKLDNTTAAMQELGRENQSLQIKHTQALNRKWAEDNEVQNCMACGKGFSVTVRRHHCRQCGNIFCAECSAKNALTPSSKKPVRVCDTCFNDLQG", "length": 1414, "header": "tr|A0A8V0YSG7-1|A0A8V0YSG7_CHICK Computationally mapped isoform of Early endosome antigen 1 OS=Gallus gallus OX=9031 GN=EEA1 PE=1 SV=1 CANONICAL=A0A8V0YKN1-1" }, "locus": { "chromosome": "1", "start_pos": 44740874, "end_pos": 44675387, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032360.1", "url": "https://www.ensembl.org/id/ENSGALT00010032360.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019134.1", "url": "https://www.ensembl.org/id/ENSGALP00010019134.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:417896", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417896", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6AIN6-1", "protein_name": "Early endosome antigen 1", "gene_name": "Eea1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDRPRRRGCSDSAPRPRRAGPPSCQLRGRPGRRALAGYLLAGSCSQPLAACGEVGAAKAASTAASSPPSSRLGCRPSRPPVVSNPHWVRRVPAAAAAAAAAAGQTMFRRILQRTPGRVGSQGSDLDSSATPINTVDVNNESSSEGFICPLCMKRCVTAIDLSEHYQQVHTELETRGQELLSDSNVTGFICPQCMKSLGSADELFKHYQAVHDAGNDSGHGGEASLALTRDDIALLRQEVQDLQASLKEEKWYSEELKKELEKYQGLQQQEAKSDGLVTDSSAELQSLEQQLEEAQTENFNIKQMKDLFEQKAAQLATEIADIKSKYDEEKGLRAAAEQKATHLTEELSKQTTVIQDLKTELLQRPGIEDVAVLKKELVQVQTLMDNMTLERERESEKLKDECKKLQSEHANSEATINQLRSELAKGPQEVAVYVQEIQKLKGSVNELTQKSQTLMEKLQKKDLDYTHLEEKHNEEALSRKNTQAALHQRDLDCQQLQARLTASEGSLQRIQGELREKGEAAQKLKEELREVETKHQHLKVEFKQLQQQREEKEQHGLQLQGEVSQLHSKLLETERQLGEAHGRLKEQRQLSSEKLMDKEQQVADLQLKLSRLEEQLKEKVTNSTELQHQLEKSKQQHQEQQALQQSTTAKLREAQNDLEQVLRQIGDKDQKIQNLEALLQKSKENISLLEKEREDLYAKIQAGEGETAVLNQLQEKNHALQQQLTQLMEKLKNQSESHKQAEENLHDQVQEQKAHLRAAQDRVLSLETSVSELSSQLNESKEKVSQLDIQIKAKTELLLSAEAAKTAQRADLQNHLDTAQNALQDKQQELNKVSAQLDQVTAKFQEKQEHCTQLESHLKDYKEKHLSLEQKAEDLEGQIKKLEANNLEVKASREQAVQSLQQQRQLSTDLELRNAELRKQLQEQKEVVSHTKLDLQNKSEALENIKQTLTKKEEEKVVLKQEFEKLSQDSEAQHKELSDRMQAAITELMVMTAQKDALLAELSTTKGKLSKVSDSLQTSRSEFEKESQKGKAAVLDLEKACKELKHQLQQQTESALKEQSELKKSLEKERETSQQLMIELNSVKGEVTQAQNTLKQKEKEEQQLQGNINQLKQATEQKKKQMEALQGELKNVTSQKAQLESKLQQQAAQAAQELAVEKGKLSALQSTYDKCQADLQQLQSDLYGKESELLATRQDLKCVEEKLALAQEDLISNRNQIGNQNKSIQELQAAKAALEQDLAKKEEVLKEQSKALQDAQREKSVKEKELVTEKSKLAEMEEIKCRQEKEIAKLKEELKSHKQESIKEVTNLKDAKQLLIQQKLELQGKVDSLKAALEQEKERQQLMREQMRKEEEKRKEEFSEKEAKLHSEIKEKEAGVKKHEENEAKLTMQVTTLNENLGTVKKEWQSSQRRVSELEKQTDDLRGEIAVLEATVQNNQDERRALLERCLKGEGEIEKLQTKVLELQRKLDNTTAAVQELGRENQSLQIKHTQALNRKWAEDNEVQNCMSCGKCFSVTVRRHHCRQCGNIFCAECSAKNALTPSSKKPVRVCDACFNDLQG", "length": 1558 }, "evidence": [ { "id": "A0A8V0YKN1", "url": "https://omabrowser.org/oma/group/A0A8V0YKN1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1QS51-1", "protein_name": "Early endosome antigen 1", "gene_name": "eea1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLRRILQMTPGKGGSQSSESEQPSADMNNESSEGFICPQCMKSHNSAEELFKHYEVFHEPGDQPSPFSPGREDLTLLRQEIQDLQASLKEERWFSEELKKELDKVQGRIATNKGLQSDGTSGEDAELEMRLNESETEKFNIKQMKDLFEQKAAQLATEIVDIKSRYDEEKSMREALEQRLANLNQDMQKEKQEKEKLSAELLQRPGVEDVEVLKKELVQVQTLMDNMTREREEESERLKGQYEQLQANFTTSEKTIAQLKAELEKGPQEAAVYTQQIHQLQSSLNNLQQQSQALSEKLSRKEKENQELEERLGHEQASKKSLQANLHQKELELQESRARVSSGEAALSRAQAELTERGEEAARLRRELGELEKNQQELKAERKQLQQQREDKENQGLQQQSEISQLHAKLLEAERQVGELQGRLKEQRQLSGEKLKDREQQAADLQLKLSRLEEELKESSTKSTDLQHQLDKSKQQHQELQTLQQSTNGKLREAQNDLEQVLRQIGDKDQKIQNLEALLQKSKESVSQLETEREDLCAKIQAGEGEAALLNQLQEKNHSLQEQITQLTDKLKNQSESHKQAQDNLHEQVQEQKTHLRSAQDRCQGLETTVTELNTQLTESREKIAQLDTQLKAKTEMLLSAEAAKNAQRADLESHLETAQNALQDKQQELSKVQAQLEEQARRLTEKQEQCSQLENGLKDSRDKLMTAEQRIETLQTQTKKAEVELTELRSGREQAQKEQSSLKKQISELEMKTKELNRLLDSEKQGASTQQEELKKKSSALTETRQKLEKAEQERGALQANLDKLSQEGQKQQAELDKKVQGLSSDLQKTQGEKETLVKEVATVKEALSKASKALKESQTQLDKEKKGSKATLEEKEKVFQKVQQELQKNSEATSKELSNVKGLLEKSIEAEKSLQSQLTALNAQLKQCQDTLKEKEKSEQQLQAELKTRQGSFSQEVKKLKTQVSELQASLAKKTEEEAKQKEQITALSKDLSSEKNRCAELQKTSDGTKESLTALQSDYYGKESELSAVRQDLKVCEEKLVLAQEELVTNRNQLSAYETQIQELKTGHTAMEIDLSKRDEKIKQQVETLQKLQKQQGQTEEQLKKEKAQCEELRESQSALEKDKNKLSADLKTLAEKNEKELKDLQAAKQLLIQQKVEMQGKVEAAQASVEKEQREHQKTRDSIKQNEQQLKAETNKIKQQLASEVKAKEEMVRQREEAEVKMSMQVTALNENVATLKREWQSSQRRVGELEKQTDELRGEIAVLEATVQNNQDERRALLERCVQGEGEMEKLQAKMLEMRRKLDDTTAAMQELGRENQSLQIKQSQSLTRKWTEDHEVQNCMACGKGFSVTVRKHHCRHCGNIFCAECSARNALTPSSKKPVRVCDNCFDELQG", "length": 1398 }, "evidence": [ { "id": "A0A8V0YKN1", "url": "https://omabrowser.org/oma/group/A0A8V0YKN1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F4ISU2-1", "protein_name": "Early endosome antigen", "gene_name": "PICC", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MEEATQVTSSEVPVVKGDVDDLKTADISVKAVNGEVPKEEKEEEDGEFIKVEKEAFDAKDDAEKADHVPVEEQKEVIERSSSGSQRELHESQEKAKELELELERVAGELKRYESENTHLKDELLSAKEKLEETEKKHGDLEVVQKKQQEKIVEGEERHSSQLKSLEDALQSHDAKDKELTEVKEAFDALGIELESSRKKLIELEEGLKRSAEEAQKFEELHKQSASHADSESQKALEFSELLKSTKESAKEMEEKMASLQQEIKELNEKMSENEKVEAALKSSAGELAAVQEELALSKSRLLETEQKVSSTEALIDELTQELEQKKASESRFKEELSVLQDLDAQTKGLQAKLSEQEGINSKLAEELKEKELLESLSKDQEEKLRTANEKLAEVLKEKEALEANVAEVTSNVATVTEVCNELEEKLKTSDENFSKTDALLSQALSNNSELEQKLKSLEELHSEAGSAAAAATQKNLELEDVVRSSSQAAEEAKSQIKELETKFTAAEQKNAELEQQLNLLQLKSSDAERELKELSEKSSELQTAIEVAEEEKKQATTQMQEYKQKASELELSLTQSSARNSELEEDLRIALQKGAEHEDRANTTHQRSIELEGLCQSSQSKHEDAEGRLKDLELLLQTEKYRIQELEEQVSSLEKKHGETEADSKGYLGQVAELQSTLEAFQVKSSSLEAALNIATENEKELTENLNAVTSEKKKLEATVDEYSVKISESENLLESIRNELNVTQGKLESIENDLKAAGLQESEVMEKLKSAEESLEQKGREIDEATTKRMELEALHQSLSIDSEHRLQKAMEEFTSRDSEASSLTEKLRDLEGKIKSYEEQLAEASGKSSSLKEKLEQTLGRLAAAESVNEKLKQEFDQAQEKSLQSSSESELLAETNNQLKIKIQELEGLIGSGSVEKETALKRLEEAIERFNQKETESSDLVEKLKTHENQIEEYKKLAHEASGVADTRKVELEDALSKLKNLESTIEELGAKCQGLEKESGDLAEVNLKLNLELANHGSEANELQTKLSALEAEKEQTANELEASKTTIEDLTKQLTSEGEKLQSQISSHTEENNQVNAMFQSTKEELQSVIAKLEEQLTVESSKADTLVSEIEKLRAVAAEKSVLESHFEELEKTLSEVKAQLKENVENAATASVKVAELTSKLQEHEHIAGERDVLNEQVLQLQKELQAAQSSIDEQKQAHSQKQSELESALKKSQEEIEAKKKAVTEFESMVKDLEQKVQLADAKTKETEAMDVGVKSRDIDLSFSSPTKRKSKKKPEASLSSSSSSGNVTTPTQTASTSHLMTVKIVTGVALISVIIGIILGRKY", "length": 1333 }, "evidence": [ { "id": "A0A8V0YKN1", "url": "https://omabrowser.org/oma/group/A0A8V0YKN1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q15075-1", "protein_name": "Early endosome antigen 1", "gene_name": "EEA1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": 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"A0A8V0YMD5-1", "uniprot_ac": "A0A8V0YMD5", "uniprot_id": "A0A8V0YMD5_CHICK", "mass": { "chemical_mass": 161759.0, "monoisotopic_mass": 161759.0 }, "refseq": { "ac": "XP_046761487", "name": "erbin isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046761487" }, "gene_names": [ { "name": "ERBIN", "type": "recommended", "evidence": [ { "id": "A0A8V0YMD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMD5" } ] }, { "name": "ERBIN", "type": "synonym", "evidence": [ { "id": "XP_046761487", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046761487" } ] } ], "protein_names": [ { "name": "Erbin", "type": "recommended", "evidence": [ { "id": "A0A8V0YMD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMD5/entry#names_and_taxonomy" } ] }, { "name": "Densin-180-like protein", "type": "synonym", "evidence": [ { "id": "A0A8V0YMD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMD5/entry#names_and_taxonomy" } ] }, { "name": "Erbb2-interacting protein", "type": "synonym", "evidence": [ { "id": "A0A8V0YMD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMD5/entry#names_and_taxonomy" } ] }, { "name": "Protein LAP2", "type": "synonym", "evidence": [ { "id": "A0A8V0YMD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMD5/entry#names_and_taxonomy" } ] }, { "name": "erbin isoform X3", "type": "synonym", "evidence": [ { "id": "XP_046761487", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046761487" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052572.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_046761487", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046761487" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMD5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMD5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ERBIN", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMD5", "locus": { "chromosome": "Z", "start_pos": 21398796, "end_pos": 21282138, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012387", "url": "https://www.ensembl.org/id/ENSGALG00010012387" } ] } } ], "crossref": [ { "id": "cd06749", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06749", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "431583", "url": "https://www.ncbi.nlm.nih.gov/gene/431583", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001478", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001478", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001611", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001611", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003591", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003591", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036034", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036034", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050614", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050614", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y975", "url": "https://www.orthodb.org/?gene=A0A8V0Y975", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YEB6", "url": "https://www.orthodb.org/?gene=A0A8V0YEB6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YHK9", "url": "https://www.orthodb.org/?gene=A0A8V0YHK9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YHL8", "url": "https://www.orthodb.org/?gene=A0A8V0YHL8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YMD5", "url": "https://www.orthodb.org/?gene=A0A8V0YMD5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23119", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23119", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23119:SF46", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23119:SF46", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00595", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00595", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13855", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13855", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_046761487", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046761487", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Y975", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y975", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y975-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y975-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YEB6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEB6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YEB6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEB6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHK9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHK9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHK9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHK9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHL8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHL8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHL8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHL8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YMD5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMD5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YMD5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMD5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTTKRNLLVRLVPCRCLRGEEETVTTLDYSHCSLEQVPKEIFTFEKTLEELYLDANQIEELPKQLFNCQSLHKLSLPDNDLTTLPASIANLINLRELDVSKNGIQEFPENIKNCKVLTVVEASVNPISKLPDGFSQLLNLTQLYLNDAFLEFLPANFGRLTKLQILELRENQLKILPKTMSRLTQLERLDLGSNEFTEVPEVLEQLSGLKEFWMDGNRLTLIPGFIGTLKQLTYLDVSKNNIEIVEEGISGCESLQDLLLSSNSLQQLPETIGSLKKVTTLKIDENQLIYLPDSIGGLVSVEELDCSFNEIETLPSSVGQLSNIRTFAADHNFLTQLPPEIGNWKYITVLFLHSNKLEFLPEEMGDMQKLKVINLSDNRLKNLPFTFTKLQQLTAMWLSDNQSKPLIPLQKEADPDTQKTVLTNYMFPQQPRTEDVMFISDNESFNPSLWEEQRKQRAQVAFECDEDKDEREAPPREGNLKRYPTPYPDELKNMVKTVQTIVHRLKDEETTEDVAKESKRESQTVSVKDVGVKTSEIVPMKNKADERKQYSAGSSVQKPTEPEAEHCTANSQMAALVKTLQNTKPIVNHEDTLEQESEELSSDEEMKMAEMRPPLIETSINQPKVVALSNNKKDDSKDADSLSDEVTHNSNQNNSNCSSPSRMSDSVSLNTDSSQDISLCSPDKETHAAVLSKIRREDENLNNLLQNGGELNITAEEKINVQEKVTNLSEYELSIEEKIGLIGKGVDLSSPTEETHKLDQINMNINKLVSEEAVPVPTERVKPQEVVSVKGFMNNMKEEGEHLENGNKYPINKVNGHPEESVHSPSKDELLRSTTADGGSSTELSISRSTEDLSPQRGGTVMKSHSITSMDPGGLKVYDIVSDSGSPQPNSVIKSSSGGADGKNIVRSKSATLLYDQPLQVFPGSLSSSDLISSTKTPFKLDSNHNPEGANVVRGSVTGGPQMFSTPQYNIQYSSSTTAKDTLWPQKQSTQVEQSSLPPSRLLRSDSTEAPSYVKHSANMNFSNHNNVRATAAYSTHQRMAGRHIDMWAVPPNDRLLPGATRHTLQRQSSVSSTASVNVGDAGPSRRAQVPEGDYLTYRDLHSMGRAPPVMSGQQRPLSARTYSIDGPNVPRPQSARPSVNEIPERTMSVSDFNYSRTSPSKRSNPRVNSEHSLLDPTGKSKVPHDWREQVLRHIEAKKLEKSMLSRSFNSNYAAVSSFHYGSSRDLHGSQGSVALSVADGRGSGVHVVRHPQASASGDQCQDEVFISGKQNYSSATLSLKDVPPDSMKKISVQIPLTNGQMCQPQRPQANYSQVHHLPPQSSVGRHPSREQLIDYLMLKVAHQPTYTQSQCSPRQSHELVKQEIRVRIDKDPELGFSISGGVGGRGNPFRPEDDGIFVTRVQPEGPASKLLQPGDKIIQANGYSFINIDHGQAVSLLKTFQNTVELIIVREISS", "length": 1455, "header": "tr|A0A8V0YMD5-1|A0A8V0YMD5_CHICK Isoform 1 of Erbin OS=Gallus gallus OX=9031 GN=ERBIN PE=1 SV=1 CANONICAL=A0A8V0YMD5-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Y975-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMD5/entry#A0A8V0Y975-1", "sequence": { "sequence": "MTTKRNLLVRLVPCRCLRGEEETVTTLDYSHCSLEQVPKEIFTFEKTLEELYLDANQIEELPKQLFNCQSLHKLSLPDNDLTTLPASIANLINLRELDVSKNGIQEFPENIKNCKVLTVVEASVNPISKLPDGFSQLLNLTQLYLNDAFLEFLPANFGRLTKLQILELRENQLKILPKTMSRLTQLERLDLGSNEFTEVPEVLEQLSGLKEFWMDGNRLTLIPGFIGTLKQLTYLDVSKNNIEIVEEGISGCESLQDLLLSSNSLQQLPETIGSLKKVTTLKIDENQLIYLPDSIGGLVSVEELDCSFNEIETLPSSVGQLSNIRTFAADHNFLTQLPPEIGNWKYITVLFLHSNKLEFLPEEMGDMQKLKVINLSDNRLKNLPFTFTKLQQLTAMWLSDNQSKPLIPLQKEADPDTQKTVLTNYMFPQQPRTEDVMFISDNESFNPSLWEEQRKQRAQVAFECDEDKDEREAPPREGNLKRYPTPYPDELKNMVKTVQTIVHRLKDEETTEDVAKESKRESQTVSVKDVGTSEIVPMKNKADERKQYSAGSSVQKPTEPEAEHCTANSQMAALVKTLQNTKPIVNHEDTLEESEELSSDEEMKMAEMRPPLIETSINQPKVVALSNNKKDDSKDADSLSDEVTHNSNQNNSNCSSPSRMSDSVSLNTDSSQDISLCSPDKETHAAVLSKIRREDENLNNLLQNGGELNITAEEKINVQEKVTNLSEYELSIEEKIGLIGKGVDLSSPTEETHKLDQINMNINKLVSEEAVPVPTERVKPQEVVSVKGFMNNMKEEGEHLENGNKYPINKVNGHPEESVHSPSKDELLRSTTADGGSSTELSISRSTEDLSPQRGGTVMKSHSITSMDPGGLKVYDIVSDSGSPQPNSVIKSSSGGADGKNIVRSKSATLLYDQPLQVFPGSLSSSDLISSTKTPFKLDSNHNPEGANVVRGSVTGGPQMFSTPQYNIQYSSSTTAKDTLWPQKQSTQVEQSSLPPSRLLRSDSTEAPSYVKHSANMNFSNHNNVRATAAYSTHQRMAGRHIDMWAVPPNDRLLPGATRHTLQRQSSVSSTASVNVGDAGPSRRAQVPEGDYLTYRDLHSMGRAPPVMSGQQRPLSARTYSIDGPNVPRPQSARPSVNEIPERTMSVSDFNYSRTSPSKRSNPRVNSEHSLLDPTGKSKVPHDWREQVLRHIEAKKLEKHPQASASGDQCQDEVFISGKQNYSSATLSLKDVPPDSMKKISVQIPLTNGQMCQPQRPQANYSQVHHLPPQSSVGRHPSREQLIDYLMLKVAHQPTYTQSQCSPRQSHELVKQEIRVRIDKDPELGFSISGGVGGRGNPFRPEDDGIFVTRVQPEGPASKLLQPGDKIIQANGYSFINIDHGQAVSLLKTFQNTVELIIVREISS", "length": 1404, "header": "tr|A0A8V0Y975-1|A0A8V0Y975_CHICK Computationally mapped isoform of Erbin OS=Gallus gallus OX=9031 GN=ERBIN PE=1 SV=1 CANONICAL=A0A8V0YMD5-1" }, "locus": { "chromosome": "Z", "start_pos": 21398564, "end_pos": 21335101, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029668.1", "url": "https://www.ensembl.org/id/ENSGALT00010029668.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017262.1", "url": "https://www.ensembl.org/id/ENSGALP00010017262.1" } ] } }, { "isoform_ac": "A0A8V0YEB6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMD5/entry#A0A8V0YEB6-1", "sequence": { "sequence": "MTTKRNLLVRLVPCRCLRGEEETVTTLDYSHCSLEQVPKEIFTFEKTLEELYLDANQIEELPKQLFNCQSLHKLSLPDNDLTTLPASIANLINLRELDVSKNGIQEFPENIKNCKVLTVVEASVNPISKLPDGFSQLLNLTQLYLNDAFLEFLPANFGRLTKLQILELRENQLKILPKTMSRLTQLERLDLGSNEFTEVPEVLEQLSGLKEFWMDGNRLTLIPGFIGTLKQLTYLDVSKNNIEIVEEGISGCESLQDLLLSSNSLQQLPETIGSLKKVTTLKIDENQLIYLPDSIGGLVSVEELDCSFNEIETLPSSVGQLSNIRTFAADHNFLTQLPPEIGNWKYITVLFLHSNKLEFLPEEMGDMQKLKVINLSDNRLKNLPFTFTKLQQLTAMWLSDNQSKPLIPLQKEADPDTQKTVLTNYMFPQQPRTEDVMFISDNESFNPSLWEEQRKQRAQVAFECDEDKDEREAPPREGNLKRYPTPYPDELKNMVKTVQTIVHRLKDEETTEDVAKESKRESQTVSVKDVGVKTSEIVPMKNKADERKQYSAGSSVQKPTEPEAEHCTANSQMAALVKTLQNTKPIVNHEDTLEQESEELSSDEEMKMAEMRPPLIETSINQPKVVALSNNKKDDSKDADSLSDEVTHNSNQNNSNCSSPSRMSDSVSLNTDSSQDISLCSPDKETHAAVLSKIRREDENLNNLLQNGGELNITAEEKINVQEKVTNLSEYELSIEEKIGLIGKGVDLSSPTEETHKLDQINMNINKLVSEEAVPVPTERVKPQEVVSVKGFMNNMKEEGEHLENGNKYPINKVNGHPEESVHSPSKDELLRSTTADGGSSTELSISRSTEDLSPQRGGTVMKSHSITSMDPGGLKVYDIVSDSGSPQPNSVIKSSSGGADGKNIVRSKSATLLYDQPLQVFPGSLSSSDLISSTKTPFKLDSNHNPEGANVVRGSVTGGPQMFSTPQYNIQYSSSTTAKDTLWPQKQSTQVEQSSLPPSRLLRSDSTEAPSYVKHSANMNFSNHNNVRATAAYSTHQRMAGRHIDMWAVPPNDRLLPGATRHTLQRQSSVSSTASVNVGDAGPSRRAQVPEGDYLTYRDLHSMGRAPPVMSGQQRPLSARTYSIDGPNVPRPQSARPSVNEIPERTMSVSDFNYSRTSPSKRSNPRVNSEHSLLDPTGKSKVPHDWREQVLRHIEAKKLEKHPQASASGDQCQDEVFISGKQNYSSATLSLKDVPPDSMKKISVQIPLTNGQMCQPQRPQANYSQVHHLPPQSSVGRHPSREQLIDYLMLKVAHQPTYTQSQCSPRQSHELVKQEIRVRIDKDPELGFSISGGVGGRGNPFRPEDDGIFVTRVQPEGPASKLLQPGDKIIQANGYSFINIDHGQAVSLLKTFQNTVELIIVREISS", "length": 1407, "header": "tr|A0A8V0YEB6-1|A0A8V0YMD5_CHICK Computationally mapped isoform of Erbin OS=Gallus gallus OX=9031 GN=ERBIN PE=1 SV=1 CANONICAL=A0A8V0YMD5-1" }, "locus": { "chromosome": "Z", "start_pos": 21398564, "end_pos": 21335101, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029681.1", "url": "https://www.ensembl.org/id/ENSGALT00010029681.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017271.1", "url": "https://www.ensembl.org/id/ENSGALP00010017271.1" } ] } }, { "isoform_ac": "A0A8V0YHK9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMD5/entry#A0A8V0YHK9-1", "sequence": { "sequence": "MTTKRNLLVRLVPCRCLRGEEETVTTLDYSHCSLEQVPKEIFTFEKTLEELYLDANQIEELPKQLFNCQSLHKLSLPDNDLTTLPASIANLINLRELDVSKNGIQEFPENIKNCKVLTVVEASVNPISKLPDGFSQLLNLTQLYLNDAFLEFLPANFGRLTKLQILELRENQLKILPKTMSRLTQLERLDLGSNEFTEVPEVLEQLSGLKEFWMDGNRLTLIPGFIGTLKQLTYLDVSKNNIEIVEEGISGCESLQDLLLSSNSLQQLPETIGSLKKVTTLKIDENQLIYLPDSIGGLVSVEELDCSFNEIETLPSSVGQLSNIRTFAADHNFLTQLPPEIGNWKYITVLFLHSNKLEFLPEEMGDMQKLKVINLSDNRLKNLPFTFTKLQQLTAMWLSDNQSKPLIPLQKEADPDTQKTVLTNYMFPQQPRTEDVMFISDNESFNPSLWEEQRKQRAQVAFECDEDKDEREAPPREGNLKRYPTPYPDELKNMVKTVQTIVHRLKDEETTEDVAKESKRESQTVSVKDVGVKTSEIVPMKNKADERKQYSAGSSVQKPTEPEAEHCTANSQMAALVKTLQNTKPIVNHEDTLEESEELSSDEEMKMAEMRPPLIETSINQPKVVALSNNKKGRKLLGPKLTVEADDSKDADSLSDEVTHNSNQNNSNCSSPSRMSDSVSLNTDSSQDISLCSPDKETHAAVLSKIRREDENLNNLLQNGGELNITAEEKINVQEKVTNLSEYELSIEEKIGLIGKGVDLSSPTEETHKLDQINMNINKLVSEEAVPVPTERVKPQEVVSVKGFMNNMKEEGEHLENGNKYPINKVNGHPEESVHSPSKDELLRSTTADGGSSTELSISRSTEDLSPQRGGTVMKSHSITSMDPGGLKVYDIVSDSGSPQPNSVIKSSSGGADGKNIVRSKSATLLYDQPLQVFPGSLSSSDLISSTKTPFKLDSNHNPEGANVVRGSVTGGPQMFSTPQYNIQYSSSTTAKDTLWPQKQSTQVEQSSLPPSRLLRSDSTEAPSYVKHSANMNFSNHNNVRATAAYSTHQRMAGRHIDMWAVPPNDRLLPGATRHTLQRQSSVSSTASVNVGDAGPSRRAQVPEGDYLTYRDLHSMGRAPPVMSGQQRPLSARTYSIDGPNVPRPQSARPSVNEIPERTMSVSDFNYSRTSPSKRSNPRVNSEHSLLDPTGKSKVPHDWREQVLRHIEAKKLEKSMLSRSFNSNYAAVSSFHYGSSRDLHGSQGSVALSVADGRGSGVHVVRHPQASASGDQCQDEVFISGKQNYSSATLSLKDVPPDSMKKISVQIPLTNGQMCQPQRPQANYSQVHHLPPQSSVGRHPSREQLIDYLMLKVAHQPTYTQSQCSPRQSHELVKQEIRVRIDKDPELGFSISGGVGGRGNPFRPEDDGIFVTRVQPEGPASKLLQPGDKIIQANGYSFINIDHGQAVSLLKTFQNTVELIIVREISS", "length": 1467, "header": "tr|A0A8V0YHK9-1|A0A8V0YMD5_CHICK Computationally mapped isoform of Erbin OS=Gallus gallus OX=9031 GN=ERBIN PE=1 SV=1 CANONICAL=A0A8V0YMD5-1" }, "locus": { "chromosome": "Z", "start_pos": 21398564, "end_pos": 21335101, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029671.1", "url": "https://www.ensembl.org/id/ENSGALT00010029671.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017265.1", "url": "https://www.ensembl.org/id/ENSGALP00010017265.1" } ] } }, { "isoform_ac": "A0A8V0YHL8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMD5/entry#A0A8V0YHL8-1", "sequence": { "sequence": "MTTKRNLLVRLVPCRCLRGEEETVTTLDYSHCSLEQVPKEIFTFEKTLEELYLDANQIEELPKQLFNCQSLHKLSLPDNDLTTLPASIANLINLRELDVSKNGIQEFPENIKNCKVLTVVEASVNPISKLPDGFSQLLNLTQLYLNDAFLEFLPANFGRTMSRLTQLERLDLGSNEFTEVPEVLEQLSGLKEFWMDGNRLTLIPGFIGTLKQLTYLDVSKNNIEIVEEGISGCESLQDLLLSSNSLQQLPETIGSLKKVTTLKIDENQLIYLPDSIGGLVSVEELDCSFNEIETLPSSVGQLSNIRTFAADHNFLTQLPPEIGNWKYITVLFLHSNKLEFLPEEMGDMQKLKVINLSDNRLKNLPFTFTKLQQLTAMWLSDNQSKPLIPLQKEADPDTQKTVLTNYMFPQQPRTEDVMFISDNESFNPSLWEEQRKQRAQVAFECDEDKDEREAPPREGNLKRYPTPYPDELKNMVKTVQTIVHRLKDEETTEDVAKESKRESQTVSVKDVGVKTSEIVPMKNKADERKQYSAGSSVQKPTEPEAEHCTANSQMAALVKTLQNTKPIVNHEDTLEESEELSSDEEMKMAEMRPPLIETSINQPKVVALSNNKKGRKLLGPKLTVEADDSKDADSLSDEVTHNSNQNNSNCSSPSRMSDSVSLNTDSSQDISLCSPDKETHAAVLSKIRREDENLNNLLQNGGELNITAEEKINVQEKVTNLSEYELSIEEKIGLIGKGVDLSSPTEETHKLDQINMNINKLVSEEAVPVPTERVKPQEVVSVKGFMNNMKEEGEHLENGNKYPINKVNGHPEESVHSPSKDELLRSTTADGGSSTELSISRSTEDLSPQRGGTVMKSHSITSMDPGGLKVYDIVSDSGSPQPNSVIKSSSGGADGKNIVRSKSATLLYDQPLQVFPGSLSSSDLISSTKTPFKLDSNHNPEGANVVRGSVTGGPQMFSTPQYNIQYSSSTTAKDTLWPQKQSTQVEQSSLPPSRLLRSDSTEAPSYVKHSANMNFSNHNNVRATAAYSTHQRMAGRHIDMWAVPPNDRLLPGATRHTLQRQSSVSSTASVNVGDAGPSRRAQVPEGDYLTYRDLHSMGRAPPVMSGQQRPLSARTYSIDGPNVPRPQSARPSVNEIPERTMSVSDFNYSRTSPSKRSNPRVNSEHSLLDPTGKSKVPHDWREQVLRHIEAKKLEKHPQASASGDQCQDEVFISGKQNYSSATLSLKDVPPDSMKKISVQIPLTNGQMCQPQRPQANYSQVHHLPPQSSVGRHPSREQLIDYLMLKVAHQPTYTQSQCSPRQSHELVKQEIRVRIDKDPELGFSISGGVGGRGNPFRPEDDGIFVTRVQPEGPASKLLQPGDKIIQANGYSFINIDHGQAVSLLKTFQNTVELIIVREISS", "length": 1400, "header": "tr|A0A8V0YHL8-1|A0A8V0YMD5_CHICK Computationally mapped isoform of Erbin OS=Gallus gallus OX=9031 GN=ERBIN PE=1 SV=1 CANONICAL=A0A8V0YMD5-1" }, "locus": { "chromosome": "Z", "start_pos": 21398564, "end_pos": 21335101, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029688.1", "url": "https://www.ensembl.org/id/ENSGALT00010029688.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017275.1", "url": "https://www.ensembl.org/id/ENSGALP00010017275.1" } ] } }, { "isoform_ac": "A0A8V0YMD5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMD5/entry#A0A8V0YMD5-1", "sequence": { "sequence": 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"length": 1455, "header": "tr|A0A8V0YMD5-1|A0A8V0YMD5_CHICK Isoform 1 of Erbin OS=Gallus gallus OX=9031 GN=ERBIN PE=1 SV=1 CANONICAL=A0A8V0YMD5-1" }, "locus": { "chromosome": "Z", "start_pos": 21398564, "end_pos": 21335101, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029676.1", "url": "https://www.ensembl.org/id/ENSGALT00010029676.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017268.1", "url": "https://www.ensembl.org/id/ENSGALP00010017268.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 7, "go_terms": [ { "name": "basolateral plasma membrane", "id": "GO:0016323", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016323", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMD5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMD5" } ], "pmid": "" }, { "name": "nuclear 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"https://www.ebi.ac.uk/QuickGO/term/GO:0005912", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMD5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMD5" } ], "pmid": "" }, { "name": "postsynaptic density", "id": "GO:0014069", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0014069", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMD5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMD5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 10, "go_terms": [ { "name": "regulation of gene expression", "id": "GO:0010468", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010468", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMD5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMD5" } ], "pmid": "" }, { "name": "negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway", "id": "GO:0070433", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070433", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMD5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMD5" } ], "pmid": "" }, { "name": "neurotransmitter receptor transport, endosome to postsynaptic membrane", "id": "GO:0098887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098887", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMD5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMD5" } ], "pmid": "" }, { "name": "response to lipopolysaccharide", "id": "GO:0032496", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032496", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMD5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMD5" } ], "pmid": "" }, { "name": "cell-cell adhesion", "id": "GO:0098609", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098609", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMD5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMD5" } ], "pmid": "" }, { "name": "negative regulation of monocyte chemotactic protein-1 production", "id": "GO:0071638", "url": 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cell apical/basal polarity", "id": "GO:0045197", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045197", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMD5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMD5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "signaling receptor binding", "id": "GO:0005102", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005102", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMD5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMD5" } ], "pmid": "" }, { "name": "protein kinase binding", "id": "GO:0019901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019901", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMD5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMD5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1021, "end_pos": 1023, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1154, "end_pos": 1156, "annotation": 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"database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YAQ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAQ8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YEF0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEF0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YEF0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEF0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YEG1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEG1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YEG1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEG1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YEG4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEG4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YEG4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEG4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJ54", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ54", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJ54-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ54-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJ59", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ59", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJ59-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ59-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "KERKGKERKGKERKGKERKGKVGKGKVGKGKVGKGKVGKGKVGKGKERLGKERLGKERKGKERKGKERKGKERKGKERKGKERKGKERKGKERKSWERKGKERLGKERKGKERKGKERKGKERKGKERKGKERKGRVGKGKVGKVKERLGKERKGKVGKGKVGKGKERLGKERLGKERKGKERKGKERKGKERKGKVGKGKERKGKERKGKERKGKERKGKERKGKERKGKERKGKERKGWERKGKVGKGKERLGKERKGKVGKGKERKGKVGKGKERLGKEWKGKERKGKERKGWVRKGKERKGKERKGKERKGKERKGKERLGKERKGKERKGKERKGKERLGKERKGWARKGWARKGWARKGKEMLGKEGKGKERKVWERKGWEKKGKERKGKERKGKERKGKERKGKERKGKERKGKERKGKERKGKERKGWVRKGCVRKGK", "length": 446, "header": "tr|A0A8V0YJ54-1|A0A8V0YJ54_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0YJ54-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Y5Z8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ54/entry#A0A8V0Y5Z8-1", "sequence": { "sequence": "GKERKGWERKGKERLGKKRLGKERKGKERKGKERKGKERKGKERKGKERKGKERKGKERLGKERLGKERLGKERLGKERLGKERKGWERKGWERKGKERKGKERKGKERKGKERKGKERKGKERKGKERKGKERLGKERKGWARKGWARKGKFGKGRERKGKKGLGKERLGKERKGKEIMGKERKGKESLGKERKGKERKGKERKGQERKGKDRKGQERKGKERKGKERKGKERKGKERKGKERKGKERLGKVGKGKERLGKEGKGMERKGWERKGWERKGKEIMGKERKGKESLGKER", "length": 299, "header": "tr|A0A8V0Y5Z8-1|A0A8V0Y5Z8_CHICK Computationally mapped isoform of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0YJ54-1" }, "locus": { "chromosome": "W", "start_pos": 2093996, "end_pos": 2087289, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028007.1", "url": "https://www.ensembl.org/id/ENSGALT00010028007.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016064.1", "url": "https://www.ensembl.org/id/ENSGALP00010016064.1" } ] } }, { "isoform_ac": "A0A8V0YAQ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ54/entry#A0A8V0YAQ8-1", "sequence": { "sequence": "MKGWESKGKVGKGKERKGWERKGWERKGKDGKGKERKGWERKVWERKGKEIMGKERKGKESLGKERKGKERKGKERKGQERKGKDRKGQERKGKERKGKERKGKERKGKERKGKERKGKVGKGWERKGKERKGWERKGWERKGKVGKGKVGKGKERKGKERKGKERKGKERKGWERKGKERKGKERKGKERKGKERKGKERKGKERKGKERKGKERLGKERKGRERKGWERKGWERKGKVGNGKERLGMERLGKERLGKERKGWERKGKERLGKERKGKERLGKERKGKERKGKERKGKERKGKERLGKERKGKERKGKERKGKE", "length": 325, "header": "tr|A0A8V0YAQ8-1|A0A8V0YAQ8_CHICK Computationally mapped isoform of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0YJ54-1" }, "locus": { "chromosome": "W", "start_pos": 2094898, "end_pos": 2089290, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028004.1", "url": "https://www.ensembl.org/id/ENSGALT00010028004.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016062.1", "url": "https://www.ensembl.org/id/ENSGALP00010016062.1" } ] } }, { "isoform_ac": "A0A8V0YEF0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ54/entry#A0A8V0YEF0-1", "sequence": { "sequence": "GKERKGWERKGKERLGKKRLGKERKGKERKGKERKGKERKGKERKGKERKGKERKGKERLGKERLGKERLGKERLGKERLGKERKGWERKGWERKGKERKGKERKGKERKGKERKGKERKGKERKGKERKGKERKGKERKGKERKGKERKGKERKGKVGKCWERLGRERKGKERKGKERKGKERKGKERKGKERKGKEKKGKERKGKERKGKERKGKERKGKERLGKERKGKERKGKERKGKERKGKERKGKERNGEERKGKERVRKVKERLGKERKGWERKGKAGLRKERLGKERLGKERKGWERKERKGKERKGKERKGKERKGKERKGKERKGKERKGKERKGKERKGKERLGKERLCKERK", "length": 365, "header": "tr|A0A8V0YEF0-1|A0A8V0YJ54_CHICK Computationally mapped isoform of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0YJ54-1" }, "locus": { "chromosome": "W", "start_pos": 2096194, "end_pos": 2087289, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028012.1", "url": "https://www.ensembl.org/id/ENSGALT00010028012.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016067.1", "url": "https://www.ensembl.org/id/ENSGALP00010016067.1" } ] } }, { "isoform_ac": "A0A8V0YEG1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ54/entry#A0A8V0YEG1-1", "sequence": { "sequence": "RKGKERKGKERKGKERKGKERKGKERKGWERKGWERKGWERKGWERKGWERKGKVGKGKVGKGKERKGKERKGKERKGKERKGKERKGKERKGKERKGKEKKGKERKVWVRKGKERKGKERKGKDRKGKERTGKDRKGKERKGKERKGKERKGKERKGKERKGKERKGWERLGKERKGWERKGWERKGKVGKGKERKGKERKGKERKGKERKGKERKGKERKGKERKGKERKGKERKGKERKGWVRKGCVRKGKERKGKERKGKERKGKERKGKERKGKERKGKERKGKERKGKERKGKERKGKERKGKERKGKERLGK", "length": 319, "header": "tr|A0A8V0YEG1-1|A0A8V0YJ54_CHICK Computationally mapped isoform of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0YJ54-1" }, "locus": { "chromosome": "W", "start_pos": 2096390, "end_pos": 2087383, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028028.1", "url": "https://www.ensembl.org/id/ENSGALT00010028028.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016077.1", "url": "https://www.ensembl.org/id/ENSGALP00010016077.1" } ] } }, { "isoform_ac": "A0A8V0YEG4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ54/entry#A0A8V0YEG4-1", "sequence": { "sequence": "GKERKGWERKGKERLGKKRLGKERKGKERKGKERKGKERKGKERKGKERKGKERKGKERLGKERLGKERLGKERLGKERLGKERKGWERKGWERKGKERKGKERKGKERKGKERKGKERKGKERKGKERKGKERKGKERKGKERKGKERKGRVGKGKERKGWERKGWESKGKVGKGKERKGWERKGWERKGKVGKGKVGKGKERKGKERKGKERKGKERKGWERKGKERKGKERKGKERKGKERKGKERKGKERKGKERKGKERLGKERKGRERKGWERKGWERKGKERLGKERKGKERLGKERKGKERKGKERKGKERKGKERLGKERKGKERKGKERKGKERKGKERKGKERKGWERK", "length": 360, "header": "tr|A0A8V0YEG4-1|A0A8V0YJ54_CHICK Computationally mapped isoform of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0YJ54-1" }, "locus": { "chromosome": "W", "start_pos": 2097489, "end_pos": 2087289, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028035.1", "url": "https://www.ensembl.org/id/ENSGALT00010028035.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016082.1", "url": "https://www.ensembl.org/id/ENSGALP00010016082.1" } ] } }, { "isoform_ac": "A0A8V0YJ54-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ54/entry#A0A8V0YJ54-1", "sequence": { "sequence": "KERKGKERKGKERKGKERKGKVGKGKVGKGKVGKGKVGKGKVGKGKERLGKERLGKERKGKERKGKERKGKERKGKERKGKERKGKERKGKERKSWERKGKERLGKERKGKERKGKERKGKERKGKERKGKERKGRVGKGKVGKVKERLGKERKGKVGKGKVGKGKERLGKERLGKERKGKERKGKERKGKERKGKVGKGKERKGKERKGKERKGKERKGKERKGKERKGKERKGKERKGWERKGKVGKGKERLGKERKGKVGKGKERKGKVGKGKERLGKEWKGKERKGKERKGWVRKGKERKGKERKGKERKGKERKGKERLGKERKGKERKGKERKGKERLGKERKGWARKGWARKGWARKGKEMLGKEGKGKERKVWERKGWEKKGKERKGKERKGKERKGKERKGKERKGKERKGKERKGKERKGKERKGWVRKGCVRKGK", "length": 446, "header": "tr|A0A8V0YJ54-1|A0A8V0YJ54_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0YJ54-1" }, "locus": { "chromosome": "W", "start_pos": 2096195, "end_pos": 2087402, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028017.1", "url": "https://www.ensembl.org/id/ENSGALT00010028017.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016070.1", "url": "https://www.ensembl.org/id/ENSGALP00010016070.1" } ] } }, { "isoform_ac": "A0A8V0YJ59-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ54/entry#A0A8V0YJ59-1", "sequence": { "sequence": "ERKGKVGKGKERKGWVRKGWVRKGKERKGKERKGKERKGKERKGKERKGKERKGKERKGWERKGWERKGWERKGWERKGWERKGKVGKGKVGKGKERKGKERKGKERKGKERKGKERKGKERKGKERKGKEKKGKERKGKERKGKERKGKEGKGKERKGWERKGWESKGKVGKGKERKGWERKGWERKGKVGKGKVGKGKERKGKERKGKERKGKERKGWERKGKERKGKERKGKERKGKERKGKERKGKERKGKERKGKERLGKERKGRERKGWERKGWERKGKERLGKERKGKERLGKERKGKERKGKERKGKERKGKERLGKERKGKERKGKERKGKERLGKERKGWEGKGKERKGKDRK", "length": 363, "header": "tr|A0A8V0YJ59-1|A0A8V0YJ59_CHICK Computationally mapped isoform of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0YJ54-1" }, "locus": { "chromosome": "W", "start_pos": 2096434, "end_pos": 2087290, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028024.1", "url": "https://www.ensembl.org/id/ENSGALT00010028024.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016075.1", "url": "https://www.ensembl.org/id/ENSGALP00010016075.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YK86-1", "uniprot_ac": "A0A8V0YK86", "uniprot_id": "A0A8V0YK86_CHICK", "mass": { "chemical_mass": 39167.0, "monoisotopic_mass": 39167.0 }, "refseq": {}, "gene_names": [ { "name": "ASB1", "type": "recommended", "evidence": [ { "id": "A0A8V0YK86", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK86" } ] } ], "protein_names": [ { "name": "Ankyrin repeat and SOCS box protein 1", "type": "recommended", "evidence": [ { "id": "A0A8V0YK86", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK86/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YK86", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK86" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ASB1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK86", "locus": { "chromosome": "7", "start_pos": 6050850, "end_pos": 6036517, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013494", "url": "https://www.ensembl.org/id/ENSGALG00010013494" } ] } } ], "crossref": [ { "id": "A0A8V0YK86", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YK86", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR001496", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001496", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036036", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036036", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036770", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036770", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YEH6", "url": "https://www.orthodb.org/?gene=A0A8V0YEH6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YK75", "url": "https://www.orthodb.org/?gene=A0A8V0YK75", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YK86", "url": "https://www.orthodb.org/?gene=A0A8V0YK86", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24171", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24171", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24171:SF10", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24171:SF10", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24173", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24173", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24173:SF27", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24173:SF27", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00023", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00023", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07525", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07525", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12796", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12796", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13606", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13606", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-8951664", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8951664", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-983168", "url": 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"A0A8V0YKH1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKH1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YKH1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKH1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YL46", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL46", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YL46-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL46-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSYCRTGATNGKDKTSGENDGQKKVQEEFDIDMDAPETERAAVAIQSQFRKFQKKKAGSQS", "length": 61, "header": "tr|A0A8V0YKG6-1|A0A8V0YKG6_CHICK Isoform 1 of Purkinje cell protein 4 OS=Gallus gallus OX=9031 GN=PCP4 PE=1 SV=1 CANONICAL=A0A8V0YKG6-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YEQ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKG6/entry#A0A8V0YEQ6-1", "sequence": { "sequence": "PIWSTLSRPLVPSTRKTWDFWKGSRREHKDDGRAATPWPRKKCEGNRTSSTWRRGGSGETLLWPSSTQRKPTGKIRRCSFPGSVVRQGTGATNGKDKTSGENDGQKKVQEEFDIDMDAPETERAAVAIQSQFRKFQKKKAGSQS", "length": 144, "header": "tr|A0A8V0YEQ6-1|A0A8V0YKG6_CHICK Computationally mapped isoform of Purkinje cell protein 4 OS=Gallus gallus OX=9031 GN=PCP4 PE=1 SV=1 CANONICAL=A0A8V0YKG6-1" }, "locus": { "chromosome": "1", "start_pos": 108277671, "end_pos": 108235025, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032589.1", "url": "https://www.ensembl.org/id/ENSGALT00010032589.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019309.1", "url": "https://www.ensembl.org/id/ENSGALP00010019309.1" } ] } }, { "isoform_ac": "A0A8V0YKG6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKG6/entry#A0A8V0YKG6-1", "sequence": { "sequence": "MSYCRTGATNGKDKTSGENDGQKKVQEEFDIDMDAPETERAAVAIQSQFRKFQKKKAGSQS", "length": 61, "header": "tr|A0A8V0YKG6-1|A0A8V0YKG6_CHICK Isoform 1 of Purkinje cell protein 4 OS=Gallus gallus OX=9031 GN=PCP4 PE=1 SV=1 CANONICAL=A0A8V0YKG6-1" }, "locus": { "chromosome": "1", "start_pos": 108277671, "end_pos": 108245469, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032588.1", "url": "https://www.ensembl.org/id/ENSGALT00010032588.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019308.1", "url": "https://www.ensembl.org/id/ENSGALP00010019308.1" } ] } }, { "isoform_ac": "A0A8V0YKH1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKG6/entry#A0A8V0YKH1-1", "sequence": { "sequence": "MTVITELQAARQGTGATNGKDKTSGENDGQKKVQEEFDIDMDAPETERAAVAIQSQFRKFQKKKAGSQS", "length": 69, "header": "tr|A0A8V0YKH1-1|A0A8V0YKH1_CHICK Computationally mapped isoform of Purkinje cell protein 4 OS=Gallus gallus OX=9031 GN=PCP4 PE=1 SV=1 CANONICAL=A0A8V0YKG6-1" }, "locus": { "chromosome": "1", "start_pos": 108277671, "end_pos": 108219316, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032593.1", "url": 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"protein_names": [ { "name": "Cupin superfamily member 1A", "type": "synonym", "evidence": [ { "id": "A0A8V0YLV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLV2/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLV2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLV2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CUPIN1A", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLV2", "locus": { "chromosome": "Z", "start_pos": 205609, "end_pos": 248005, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012283", "url": "https://www.ensembl.org/id/ENSGALG00010012283" } ] } } ], "crossref": [ { "id": "A0A8V0YLV2", "url": 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"categories": [ "Protein" ] }, { "id": "A0A8V0YLV2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLV2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLV2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLV2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDNRAFEMQPEGAARSWKGKDGPQREAPQSNGTLRKLFALCLLAGVMSTALSVASLALVYSKAGGLVREMSANEGGVVNEEGVNEEGGGGGGARFRFFYRLSRTEPQKYPGGQIQWATSRSKRDLYPDPEGLQFGESLRQHQSHMSVALLRIKAGGLRVPHWHFNAAEHGYVLQGTAWVGVASGANATTYNATVGQAVFFPPGAVHWLKNVGGGELAVVLFFGSHEEVKTLDVDEAFFGTAEDIAARALQPSGGLEFIRSFRKASEDQRVNLPPNLAQLVHSAAYGRSEDSRVWRYFYDLAASPLHPFRGGSFRWAPYRPSRTFMSPMERIYTQSLDESSAPLTLALLRIHPNELGQPHLHGNANELAYVVSGRGRAGLVTEKGLKVEMEVGVGDVVFFPAGTQHYLEAGGDEGLLLVVAYSTGKKVSRGVEWVIIWQPWGSIGSNGSLFGRDGSLLGQMGPYLAAMGHYWELWVIIWQLWGCMETYGSLFGSHGSLLG", "length": 499, "header": "tr|A0A8V0YLV2-1|A0A8V0YLV2_CHICK Isoform 1 of Cupin superfamily member 1A OS=Gallus gallus OX=9031 GN=CUPIN1A PE=4 SV=1 CANONICAL=A0A8V0YLV2-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YEY7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLV2/entry#A0A8V0YEY7-1", "sequence": { "sequence": "MDNRAFEMQPEGAARSWKGKDGPQREAPQSNGTLRKLFALCLLAGVMSTALSVASLALVYSKAGGLVREMSANEGGVVNEEGVNEEGGGGGGARFRFFYRLSRTEPQKYPGGQIQWATSRSKRDLYPDPEGLQFGESLRQHQSHMSVALLRIKAGGLRVPHWHFNAAEHGYVLQGTAWVGVASGANATTYNATVGQAVFFPPGAVHWLKNVGGGELAVVLFFGSHEEVKTLDVDEAFFGTAEDIAARALQPSGGLEFIRSFRKASEDQRVNLPPNLAQLVHSAAYGRSEDSRVWRYFYDLAASPLHPFRGGSFRWAPYRPSRTFMSPMERIYTQSLDESSAPLTLALLRIHPNELGQPHLHGNANELAYVVSGRGRAGLVTEKGLKVEMEVGVGDVVFFPAGTQHYLEAGGDEGLLLVVAYSTGKKELKTLRMNQYFKATADHILAQLFRKEQREFQRFPRS", "length": 462, "header": "tr|A0A8V0YEY7-1|A0A8V0YLV2_CHICK Computationally mapped isoform of Cupin superfamily member 1A OS=Gallus gallus OX=9031 GN=CUPIN1A PE=4 SV=1 CANONICAL=A0A8V0YLV2-1" }, "locus": { "chromosome": "Z", "start_pos": 248005, "end_pos": 205661, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029407.1", "url": "https://www.ensembl.org/id/ENSGALT00010029407.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017082.1", "url": "https://www.ensembl.org/id/ENSGALP00010017082.1" } ] } }, { "isoform_ac": "A0A8V0YLV2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLV2/entry#A0A8V0YLV2-1", "sequence": { "sequence": "MDNRAFEMQPEGAARSWKGKDGPQREAPQSNGTLRKLFALCLLAGVMSTALSVASLALVYSKAGGLVREMSANEGGVVNEEGVNEEGGGGGGARFRFFYRLSRTEPQKYPGGQIQWATSRSKRDLYPDPEGLQFGESLRQHQSHMSVALLRIKAGGLRVPHWHFNAAEHGYVLQGTAWVGVASGANATTYNATVGQAVFFPPGAVHWLKNVGGGELAVVLFFGSHEEVKTLDVDEAFFGTAEDIAARALQPSGGLEFIRSFRKASEDQRVNLPPNLAQLVHSAAYGRSEDSRVWRYFYDLAASPLHPFRGGSFRWAPYRPSRTFMSPMERIYTQSLDESSAPLTLALLRIHPNELGQPHLHGNANELAYVVSGRGRAGLVTEKGLKVEMEVGVGDVVFFPAGTQHYLEAGGDEGLLLVVAYSTGKKVSRGVEWVIIWQPWGSIGSNGSLFGRDGSLLGQMGPYLAAMGHYWELWVIIWQLWGCMETYGSLFGSHGSLLG", "length": 499, "header": "tr|A0A8V0YLV2-1|A0A8V0YLV2_CHICK Isoform 1 of Cupin superfamily member 1A OS=Gallus gallus OX=9031 GN=CUPIN1A PE=4 SV=1 CANONICAL=A0A8V0YLV2-1" }, "locus": { "chromosome": "Z", "start_pos": 248005, "end_pos": 210682, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029406.1", "url": "https://www.ensembl.org/id/ENSGALT00010029406.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017081.1", "url": "https://www.ensembl.org/id/ENSGALP00010017081.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A287AFS7-1", "protein_name": "Cupin superfamily member 1", "gene_name": "CUPIN1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDNLAFEMHEDAKQNVVSMGKATTISRLEKKRQWSLMSIFLVCLLACTITTAVGVLILSLVYVNNSQPHSNVHLQPETQPLQTATIPIMQKAIDPKFQFLNHLPKSKVFEFPGGAIQWARYRNNVKDYLSIEEEAFGSSLNSQRSQMTLGTLRIKSSGLRVPHWHFNANEHGYLVQGTAWIGVIDSGAVVTTYNITAGQVIFFPKNTVHWIKNVGNEDCFFLLFFSTHDELQTLDVDDVFFSTPEDIASRSLKPEGGINFIRTFHKQKEDQGVNLPPNLAELVVNASYIQSPDSRVWRYFYDLKGSKEYLFPGGIIQLAQCWKNRSELSNNEKIFSEFLNQHENALTLSTLRIYNNGLRQPHFHFNANEMGYVISGCAEVAIINAQSTIEFNIHIGDVIFFPIGTQHYIKSTCDEDLLLVLAFSTGDQLQTLDMDDYLQATADHILAQLFFKKQSEFKKIPKFKEDQAINLP", "length": 472 }, "evidence": [ { "id": "A0A8V0YLV2", "url": "https://omabrowser.org/oma/group/A0A8V0YLV2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLV2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLV2" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLV2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLV2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "positive regulation of cell population proliferation", "id": "GO:0008284", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008284", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLV2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLV2" } ], "pmid": "" }, { "name": "regulation of apoptotic process", "id": "GO:0042981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042981", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLV2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLV2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 186, "end_pos": 188, "annotation": "n_glycosylation_sequon" }, { "start_pos": 191, "end_pos": 193, "annotation": "n_glycosylation_sequon" }, { "start_pos": 31, "end_pos": 33, "annotation": "n_glycosylation_sequon" }, { "start_pos": 446, "end_pos": 448, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YLV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLV2" }, { "id": "SM00835", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00835" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Cupin type-1", "eco_id": "ECO_0000259", "start_pos": 123, "end_pos": 245, "start_aa": "Arg", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 186, "end_pos": 188 }, { "start_pos": 191, "end_pos": 193 }, { "start_pos": 31, "end_pos": 33 }, { "start_pos": 446, "end_pos": 448 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YM27-1", "uniprot_ac": "A0A8V0YM27", "uniprot_id": "A0A8V0YM27_CHICK", "mass": { "chemical_mass": 87757.0, "monoisotopic_mass": 87757.0 }, "refseq": { "ac": "XP_015138424", "name": "probable C-mannosyltransferase DPY19L4 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015138424" }, "gene_names": [ { "name": "DPY19L4", "type": "recommended", "evidence": [ { "id": "A0A8V0YM27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM27" } ] }, { "name": "DPY19L4", "type": "synonym", "evidence": [ { "id": "XP_015138424", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015138424" } ] } ], "protein_names": [ { "name": "Dpy-19 like 4", "type": "synonym", "evidence": [ { "id": "A0A8V0YM27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM27/entry#names_and_taxonomy" } ] }, { "name": "probable C-mannosyltransferase DPY19L4 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_015138424", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015138424" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052533.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015138424.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015138424", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015138424" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YM27", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM27" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "DPY19L4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM27", "locus": { "chromosome": "2", "start_pos": 125892564, "end_pos": 125862914, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012320", "url": "https://www.ensembl.org/id/ENSGALG00010012320" } ] } } ], "crossref": [ { "id": "A0A8V0YM27", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YM27", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd20180", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd20180", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "420229", "url": "https://www.ncbi.nlm.nih.gov/gene/420229", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR018732", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018732", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047464", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047464", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:420229", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420229", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0Y8W9", "url": "https://www.orthodb.org/?gene=A0A8V0Y8W9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YF50", "url": "https://www.orthodb.org/?gene=A0A8V0YF50", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YM27", "url": "https://www.orthodb.org/?gene=A0A8V0YM27", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31488", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31488", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31488:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31488:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10034", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10034", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015138424", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015138424", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Y8W9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y8W9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y8W9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y8W9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YF50", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF50", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YF50-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF50-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YM27", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM27", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YM27-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM27-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRERSRPRGRREGGGGGGRNAGGAASPPRTERRGAPAAGGGRRMEEGAADLRQRRKQNCTESDKMAPEERHKENSKLGRSPKYMLIQRFAKLFFGCLAAVTSGMMYAVYLSTYHERKFWFSSRQELEREITFQGDSAIYYSFYKELLKAPSFERGVYELTHNNKTVSMKTINAVQQMTLYPELIASVLYQASGSEEVIEPVYFYIGIVFGLQGIYVTALFVTSWVMSGTWLAGMLTVAWFIINRTDTTRIDYSIPSRENWALPYFACQVAALTGYLKKNLNCSAEKFCYLLVSASTYTFMMMWEYSHYLLFVQAVSLFLLDSFALAQSEKVHEVYKIYMFSLFLGYLLQFENSALLVSPLLSLVAALMLSKYLQMNVKKGTFMSRLLKIMYIYLVLTVTLTLNLLLKMFVPHKENEHLLKFLEIKLGLNTTKNFTMNWLLCQESLQAPSQDFFLRLTQSSLLPFYILVLIICLFSVTQVVFRRICGEPLKETVKLEDGRIGERPEIVYHVIHTILLGSLAMCLEGMKYLWTPYVCMLAAFGVCSPELWMTLFKWLRLKAVHPILLALILSMAVPTIIGFSLWKEFFPRIMTELSELQEFYDPDTVELMTWIKRQAPVAAVFAGSPQLMGVIKLCTGWMVSSLPLYNDDDLLKRNENIYQIYSKRSAEDIYKILTSYKANFLIIEDSICNEVGPVRGCRVKDLLDIANGHVVCEEGDSYAYSKYGRFCHEIKMNYSPYVNYFTRVYWNRSYFVYRINTVISFQS", "length": 763, "header": "tr|A0A8V0YM27-1|A0A8V0YM27_CHICK Isoform 1 of Dpy-19 like 4 OS=Gallus gallus OX=9031 GN=DPY19L4 PE=3 SV=1 CANONICAL=A0A8V0YM27-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Y8W9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM27/entry#A0A8V0Y8W9-1", "sequence": { "sequence": "MAPEERHKENSKLGRSPKYMLIQRFAKLFFGCLAAVTSGMMYAVYLSTYHERKFWFSSRQELEREITFQGDSAIYYSFYKELLKAPSFERGVYELTHNNKTVSMKTINAVQQMTLYPELIASVLYQASGSEEVIEPVYFYIGIVFGLQGIYVTALFVTSWVMSGTWLAGMLTVAWFIINRTDTTRIDYSIPSRENWALPYFACQVAALTGYLKKNLNCSAEKFCYLLVSASTYTFMMMWEYSHYLLFVQAVSLFLLDSFALAQSEKVHEVYKIYMFSLFLGYLLQFENSALLVSPLLSLVAALMLSKYLQMNVKKGTFMSRLLKIMYIYLVLTVTLTLNLLLKMFVPHKENEHLLKFLEIKLGLNTTKNFTMNWLLCQESLQAPSQDFFLRLTQSSLLPFYILVLIICLFSVTQVVFRRICGEPLKETVKLEDGRIGERPEIVYHVIHTILLGSLAMCLEGMKYLWTPYVCMLAAFGVCSPELWMTLFKWLRLKAVHPILLALILSMAVPTIIGFSLWKEFFPRIMTELSELQEFYDPDTVELMTWIKRQAPVAAVFAGSPQLMGVIKLCTGWMVSSLPLYNDDDLLKRNENIYQIYSKRSAEDIYKILTSYKANFLIIEDSICNEVGPVRGCRVKDLLDIANGHVVCEEGDSYAYSKYGRFCHEIKMNYSPYVNYFTRVYWNRSYFVYRINTVISFQS", "length": 699, "header": "tr|A0A8V0Y8W9-1|A0A8V0Y8W9_CHICK Computationally mapped isoform of Dpy-19 like 4 OS=Gallus gallus OX=9031 GN=DPY19L4 PE=3 SV=1 CANONICAL=A0A8V0YM27-1" }, "locus": { "chromosome": "2", "start_pos": 125889449, "end_pos": 125865674, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029503.1", "url": "https://www.ensembl.org/id/ENSGALT00010029503.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017146.1", "url": "https://www.ensembl.org/id/ENSGALP00010017146.1" } ] } }, { "isoform_ac": "A0A8V0YF50-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM27/entry#A0A8V0YF50-1", "sequence": { "sequence": "MGFSGCSFRNTVAITSYKMSSGAADLRQRRKQNCTESDKMAPEERHKENSKLGRSPKYMLIQRFAKLFFGCLAAVTSGMMYAVYLSTYHERKFWFSSRQELEREITFQGDSAIYYSFYKELLKAPSFERGVYELTHNNKTVSMKTINAVQQMTLYPELIASVLYQASGSEEVIEPVYFYIGIVFGLQGIYVTALFVTSWVMSGTWLAGMLTVAWFIINRTDTTRIDYSIPSRENWALPYFACQVAALTGYLKKNLNCSAEKFCYLLVSASTYTFMMMWEYSHYLLFVQAVSLFLLDSFALAQSEKVHEVYKIYMFSLFLGYLLQFENSALLVSPLLSLVAALMLSKYLQMNVKKGTFMSRLLKIMYIYLVLTVTLTLNLLLKMFVPHKENEHLLKFLEIKLGLNTTKNFTMNWLLCQESLQAPSQDFFLRLTQSSLLPFYILVLIICLFSVTQVVFRRICGEPLKETVKLEDGRIGERPEIVYHVIHTILLGSLAMCLEGMKYLWTPYVCMLAAFGVCSPELWMTLFKWLRLKAVHPILLALILSMAVPTIIGFSLWKEFFPRIMTELSELQEFYDPDTVELMTWIKRQAPVAAVFAGSPQLMGVIKLCTGWMVSSLPLYNDDDLLKRNENIYQIYSKRSAEDIYKILTSYKANFLIIEDSICNEVGPVRGCRVKDLLDIANGHVVCEEGDSYAYSKYGRFCHEIKMNYSPYVNYFTRVYWNRSYFVYRINTVISFQS", "length": 738, "header": "tr|A0A8V0YF50-1|A0A8V0YM27_CHICK Computationally mapped isoform of Dpy-19 like 4 OS=Gallus gallus OX=9031 GN=DPY19L4 PE=3 SV=1 CANONICAL=A0A8V0YM27-1" }, "locus": { "chromosome": "2", "start_pos": 125889449, "end_pos": 125865557, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029497.1", "url": "https://www.ensembl.org/id/ENSGALT00010029497.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017143.1", "url": "https://www.ensembl.org/id/ENSGALP00010017143.1" } ] } }, { "isoform_ac": "A0A8V0YM27-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM27/entry#A0A8V0YM27-1", "sequence": { "sequence": "MRERSRPRGRREGGGGGGRNAGGAASPPRTERRGAPAAGGGRRMEEGAADLRQRRKQNCTESDKMAPEERHKENSKLGRSPKYMLIQRFAKLFFGCLAAVTSGMMYAVYLSTYHERKFWFSSRQELEREITFQGDSAIYYSFYKELLKAPSFERGVYELTHNNKTVSMKTINAVQQMTLYPELIASVLYQASGSEEVIEPVYFYIGIVFGLQGIYVTALFVTSWVMSGTWLAGMLTVAWFIINRTDTTRIDYSIPSRENWALPYFACQVAALTGYLKKNLNCSAEKFCYLLVSASTYTFMMMWEYSHYLLFVQAVSLFLLDSFALAQSEKVHEVYKIYMFSLFLGYLLQFENSALLVSPLLSLVAALMLSKYLQMNVKKGTFMSRLLKIMYIYLVLTVTLTLNLLLKMFVPHKENEHLLKFLEIKLGLNTTKNFTMNWLLCQESLQAPSQDFFLRLTQSSLLPFYILVLIICLFSVTQVVFRRICGEPLKETVKLEDGRIGERPEIVYHVIHTILLGSLAMCLEGMKYLWTPYVCMLAAFGVCSPELWMTLFKWLRLKAVHPILLALILSMAVPTIIGFSLWKEFFPRIMTELSELQEFYDPDTVELMTWIKRQAPVAAVFAGSPQLMGVIKLCTGWMVSSLPLYNDDDLLKRNENIYQIYSKRSAEDIYKILTSYKANFLIIEDSICNEVGPVRGCRVKDLLDIANGHVVCEEGDSYAYSKYGRFCHEIKMNYSPYVNYFTRVYWNRSYFVYRINTVISFQS", "length": 763, "header": "tr|A0A8V0YM27-1|A0A8V0YM27_CHICK Isoform 1 of Dpy-19 like 4 OS=Gallus gallus OX=9031 GN=DPY19L4 PE=3 SV=1 CANONICAL=A0A8V0YM27-1" }, "locus": { "chromosome": "2", "start_pos": 125889449, "end_pos": 125863025, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029510.1", "url": "https://www.ensembl.org/id/ENSGALT00010029510.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017152.1", "url": "https://www.ensembl.org/id/ENSGALP00010017152.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:420229", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420229", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YM27", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM27" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YM27", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM27" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "glycosyltransferase activity", "id": "GO:0016757", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016757", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YM27", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM27" } ], "pmid": "" }, { "name": "mannosyltransferase activity", "id": "GO:0000030", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000030", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YM27", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM27" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 163, "end_pos": 165, "annotation": "n_glycosylation_sequon" }, { "start_pos": 243, "end_pos": 245, "annotation": "n_glycosylation_sequon" }, { "start_pos": 281, "end_pos": 283, "annotation": "n_glycosylation_sequon" }, { "start_pos": 429, "end_pos": 431, "annotation": "n_glycosylation_sequon" }, { "start_pos": 433, "end_pos": 435, "annotation": "n_glycosylation_sequon" }, { "start_pos": 58, "end_pos": 60, "annotation": "n_glycosylation_sequon" }, { "start_pos": 733, "end_pos": 735, "annotation": "n_glycosylation_sequon" }, { "start_pos": 747, "end_pos": 749, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 163, "end_pos": 165 }, { "start_pos": 243, "end_pos": 245 }, { "start_pos": 281, "end_pos": 283 }, { "start_pos": 429, "end_pos": 431 }, { "start_pos": 433, "end_pos": 435 }, { "start_pos": 58, "end_pos": 60 }, { "start_pos": 733, "end_pos": 735 }, { "start_pos": 747, "end_pos": 749 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YL03-1", "uniprot_ac": "A0A8V0YL03", "uniprot_id": "A0A8V0YL03_CHICK", "mass": { "chemical_mass": 46394.0, "monoisotopic_mass": 46394.0 }, "refseq": { "ac": "XP_040545692", "name": "transcription factor AP-2-epsilon isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040545692" }, "gene_names": [ { "name": "TFAP2E", "type": "recommended", "evidence": [ { "id": "A0A8V0YL03", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL03" } ] }, { "name": "TFAP2E", "type": "synonym", "evidence": [ { "id": "XP_040545692", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040545692" } ] } ], "protein_names": [ { "name": "Transcription factor AP-2 epsilon", "type": "synonym", "evidence": [ { "id": "A0A8V0YL03", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL03/entry#names_and_taxonomy" } ] }, { "name": "transcription factor AP-2-epsilon isoform X2", "type": "synonym", "evidence": [ { "id": "XP_040545692", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040545692" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052595.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040545692", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040545692" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YL03", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL03" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TFAP2E", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL03", "locus": { "chromosome": "23", "start_pos": 4648806, "end_pos": 4666164, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013698", "url": "https://www.ensembl.org/id/ENSGALG00010013698" } ] } } ], "crossref": [ { "id": "A0A8V0YL03", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YL03", "database": "AlphaFoldDB", "categories": [] }, { "id": "419631", "url": "https://www.ncbi.nlm.nih.gov/gene/419631", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013854", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013854", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:419631", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419631", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QEAGYPH", "url": "https://omabrowser.org/oma/group/QEAGYPH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YF59", "url": "https://www.orthodb.org/?gene=A0A8V0YF59", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YF62", "url": "https://www.orthodb.org/?gene=A0A8V0YF62", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YL03", "url": "https://www.orthodb.org/?gene=A0A8V0YL03", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YLI7", "url": "https://www.orthodb.org/?gene=A0A8V0YLI7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10812", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10812", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10812:SF13", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10812:SF13", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03299", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03299", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-8866907", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8866907", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_040545692", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040545692", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YF59", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF59", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YF59-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF59-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YF62", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF62", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YF62-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF62-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YL03", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL03", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YL03-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL03-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLI7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLI7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLI7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLI7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLVHSYPGMDRAEGLPGASAGARLPQLPALNQTPYGSAPPLCHTPAADFQPPYFPPPYPQPPLPYPQGQEPAYPHLADPYAALSPLHQHQQPAWPPQRSRQDDAGLLSQTHRALGLDPRREYPAVPRLLHGLPDGGHGLPDGPLGLHGLGHHGLEEIQAADDGGMNLLDQSVIKKVPIPSKANGTIPSLMNKDGLIGGVTNPNEVFCSVPGRLSLLSSTSKYKVTVGEVQRRLSPPECLNASLLGGVLRRAKSKNGGRCLRERLEKIGLNLPAGRRKAANVTLLTSLVEGEAVHLARDFGYVCETEFPAKAAAEYLCRQHSDPTELHTRKNMLLATKQICKEFADLIAQDRSPLGNSRPSLILEPGVQSCLTHFSLITHGFGGPAICAALTAFQNYLVESLKGLDKMFISSTGNGHTAGDSKASEKEGKHRK", "length": 432, "header": "tr|A0A8V0YL03-1|A0A8V0YL03_CHICK Isoform 1 of Transcription factor AP-2 epsilon OS=Gallus gallus OX=9031 GN=TFAP2E PE=3 SV=1 CANONICAL=A0A8V0YL03-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YF59-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL03/entry#A0A8V0YF59-1", "sequence": { "sequence": "MGWVTSVLPSQHPGLGWAQLCSVPSIHPSVKGMSTQTIPDQSMCDVQLCPHSSTVMSQMLLSHVSVTRSPTLGSAHPVGEVPRCQGQGSPRTSPELTSQCGDPRATSPLPSIPPAKCQQGSAPSTSHPRPDGVAPSSAIVSPLCAPHRSAGDTLAAAPVSHFLLSAGWLRCSDHLLLAGAGKQQLKIEGDFWFTQMTRDNFASPKAKETKLSGFNGSLSPSCSMFMGKQAAEQTRQTAVPIPSKANGTIPSLMNKDGLIGGVTNPNEVFCSVPGRLSLLSSTSKYKVTVGEVQRRLSPPECLNASLLGGVLRRAKSKNGGRCLRERLEKIGLNLPAGRRKAANVTLLTSLVEGEAVHLARDFGYVCETEFPAKAAAEYLCRQHSDPTELHTRKNMLLATKQICKEFADLIAQDRSPLGNSRPSLILEPGVQSCLTHFSLITHGFGGPAICAALTAFQNYLVESLKGLDKMFISSTGNGHTAGDSKASEKEGKHRK", "length": 495, "header": "tr|A0A8V0YF59-1|A0A8V0YL03_CHICK Computationally mapped isoform of Transcription factor AP-2 epsilon OS=Gallus gallus OX=9031 GN=TFAP2E PE=3 SV=1 CANONICAL=A0A8V0YL03-1" }, "locus": { "chromosome": "23", "start_pos": 4656237, "end_pos": 4649911, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032897.1", "url": "https://www.ensembl.org/id/ENSGALT00010032897.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019469.1", "url": "https://www.ensembl.org/id/ENSGALP00010019469.1" } ] } }, { "isoform_ac": "A0A8V0YF62-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL03/entry#A0A8V0YF62-1", "sequence": { "sequence": "MRDRAEGLPGASAGARLPQLPALNQTPYGSAPPLCHTPAADFQPPYFPPPYPQPPLPYPQGQEPAYPHLADPYAALSPLHQHQQPAWPPQRSRQDDAGLLSQTHRALGLDPRREYPAVPRLLHGLPDGGHGLPDGPLGLHGLGHHGLEEIQAADDGGMNLLDQSVIKKVPIPSKANGTIPSLMNKDGLIGGVTNPNEVFCSVPGRLSLLSSTSKYKVTVGEVQRRLSPPECLNASLLGGVLRRAKSKNGGRCLRERLEKIGLNLPAGRRKAANVTLLTSLVEGEAVHLARDFGYVCETEFPAKAAAEYLCRQHSDPTELHTRKNMLLATKQICKEFADLIAQDRSPLGNSRPSLILEPGVQSCLTHFSLITHGFGGPAICAALTAFQNYLVESLKGLDKMFISSTGNGHTAGDSKASEKEGKHRK", "length": 425, "header": "tr|A0A8V0YF62-1|A0A8V0YL03_CHICK Computationally mapped isoform of Transcription factor AP-2 epsilon OS=Gallus gallus OX=9031 GN=TFAP2E PE=3 SV=1 CANONICAL=A0A8V0YL03-1" }, "locus": { "chromosome": "23", "start_pos": 4666073, "end_pos": 4649911, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032912.1", "url": "https://www.ensembl.org/id/ENSGALT00010032912.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019474.1", "url": "https://www.ensembl.org/id/ENSGALP00010019474.1" } ] } }, { "isoform_ac": "A0A8V0YL03-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL03/entry#A0A8V0YL03-1", "sequence": { "sequence": "MLVHSYPGMDRAEGLPGASAGARLPQLPALNQTPYGSAPPLCHTPAADFQPPYFPPPYPQPPLPYPQGQEPAYPHLADPYAALSPLHQHQQPAWPPQRSRQDDAGLLSQTHRALGLDPRREYPAVPRLLHGLPDGGHGLPDGPLGLHGLGHHGLEEIQAADDGGMNLLDQSVIKKVPIPSKANGTIPSLMNKDGLIGGVTNPNEVFCSVPGRLSLLSSTSKYKVTVGEVQRRLSPPECLNASLLGGVLRRAKSKNGGRCLRERLEKIGLNLPAGRRKAANVTLLTSLVEGEAVHLARDFGYVCETEFPAKAAAEYLCRQHSDPTELHTRKNMLLATKQICKEFADLIAQDRSPLGNSRPSLILEPGVQSCLTHFSLITHGFGGPAICAALTAFQNYLVESLKGLDKMFISSTGNGHTAGDSKASEKEGKHRK", "length": 432, "header": "tr|A0A8V0YL03-1|A0A8V0YL03_CHICK Isoform 1 of Transcription factor AP-2 epsilon OS=Gallus gallus OX=9031 GN=TFAP2E PE=3 SV=1 CANONICAL=A0A8V0YL03-1" }, "locus": { "chromosome": "23", "start_pos": 4665120, "end_pos": 4649911, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032909.1", "url": "https://www.ensembl.org/id/ENSGALT00010032909.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019473.1", "url": "https://www.ensembl.org/id/ENSGALP00010019473.1" } ] } }, { "isoform_ac": "A0A8V0YLI7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL03/entry#A0A8V0YLI7-1", "sequence": { "sequence": "MLVHSYPGMDRAEGLPGASAGARLPQLPALNQTPYGSAPPLCHTPAADFQPPYFPPPYPQPPLPYPQGQEPAYPHLADPYAALSPLHQHQQPAWPPQRSRQDDAGLLSQTHRALGLDPRREYPAVPRLLHGLPDGGHGLPDGPLGLHGLGHHGLEEIQAADDGGMNLLDQSVIKKGWLRCSDHLLLAGAGKQQLKIEGDFWFTQMTRDNFASPKAKETKLSGFNGSLSPSCSMFMGKQAAEQTRQTAVPIPSKANGTIPSLMNKDGLIGGVTNPNEVFCSVPGRLSLLSSTSKYKVTVGEVQRRLSPPECLNASLLGGVLRRAKSKNGGRCLRERLEKIGLNLPAGRRKAANVTLLTSLVEGEAVHLARDFGYVCETEFPAKAAAEYLCRQHSDPTELHTRKNMLLATKQICKEFADLIAQDRSPLGNSRPSLILEPGVQSCLTHFSLITHGFGGPAICAALTAFQNYLVESLKGLDKMFISSTGNGHTAGDSKASEKEGKHRK", "length": 504, "header": "tr|A0A8V0YLI7-1|A0A8V0YLI7_CHICK Computationally mapped isoform of Transcription factor AP-2 epsilon OS=Gallus gallus OX=9031 GN=TFAP2E PE=3 SV=1 CANONICAL=A0A8V0YL03-1" }, "locus": { "chromosome": "23", "start_pos": 4665120, "end_pos": 4649911, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032904.1", "url": "https://www.ensembl.org/id/ENSGALT00010032904.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019471.1", "url": "https://www.ensembl.org/id/ENSGALP00010019471.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:419631", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419631", "resource": "KEGG Pathway" }, { "id": "R-GGA-8866907", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8866907", "resource": "Reactome", "description": "Activation of the TFAP2 (AP-2) family of transcription factors" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287A2X4-1", "protein_name": "Transcription factor AP-2 epsilon", "gene_name": "TFAP2E", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MLVHTYSAMERPDGLGAAAGGARLSSLPQAAYGPAPPLCHTPAAAAAAADFQPPYFPPPYPQPPLPYGQASDAAAAFPHLAGDPYGGLAPLAQPQPPQAAWAAPRAAARAHDEPPGLLAPPARALGLDPRREYAASVPRLLHGLADGAHGLADAPLGLPGLAAPPSLEDMQVRPEGSGMVPIPSKASSLSALSLAKDSLVGGITNPSEVFCSVPGRLSLLSSTSKYKVTVGEVQRRLSPPECLNASLLGGVLRRAKSKNGGRCLRERLEKIGLNLPAGRRKAANVTLLTSLVEGEAVHLARDFGYVCETEFPAKAAAEYLCRQHADPGELHSRKSMLLAAKQICKEFADLMAQDRSPLGNSRPALILEPGVQSCLTHFSLITHGFGGPAICAALTAFQNYLLESLKGLDKMFLSSTGSGHGDTKASEKDAKHRK", "length": 434 }, "evidence": [ { "id": "A0A8V0YL03", "url": "https://omabrowser.org/oma/group/A0A8V0YL03/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "D3ZJ69-1", "protein_name": "Transcription factor AP-2 epsilon", "gene_name": "Tfap2e", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLVHTYSAMERPDGLCAAAGGTRLSSLPQAAYGPAPPLCHTPAASATTDYHPPYFPPPYPQAQLPYGQGPDAAAAFPHLAPDPYGGLAPLAQPQPPQAAWAAPRAAARAHDEPPGLLAPPARALGLDPRRDYAAAVPRLLHSLADGAHGLADAPLGLPGLAAPPGLEELQAIDDPGMSLLDQSVIKKVPVPSKAGSLSTLSLSKDSLVGGINNPSEVFCSVPGRLSLLSSTSKYKVTVGEVQRRLSPPECLNASLLGGVLRRAKSKNGGRCLRERLEKIGLNLPAGRRKAANVTLLTSLVEGEAVHLARDFGYVCETEFPAKAAAEYLGRQHADPGELHSRKSMLLAAKQICKEFADLMAQDRSPLGNSRPALILEPGVQSCLTHFSLITHGFGGPAICAALTAFQNYLLESLKGLDKMFLSSAGSGHGETKASEKDAKHRK", "length": 442 }, "evidence": [ { "id": "A0A8V0YL03", "url": "https://omabrowser.org/oma/group/A0A8V0YL03/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6P0E7-1", "protein_name": "Transcription factor AP-2-epsilon", "gene_name": "tfap2e", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLVHSYSSMERADGLSSSSPGGRLSQLNQAAYSSAPPLCHTPASDFQPPYFPPPYPQSSLSYSQSQDGGYPHLPEPYPSLNSLHQHQQAAWHSQRSRSEDAGLLSQPHRALSLDPRREYPGVPRLLTHGLGDGAAALGDGPLGMHAVHHGLDDIQGLEEASALGILDHSVIKKVPLPSKLNGSTISALSLSKEGLGLGGVSNPAEVFCSVPGRLSLLSSTSKYKVTVGEVQRRLAPPECLNASLLGGVLRRAKSKNGGRCLRERLEKIGLNLPAGRRKAANVTLLTALVEGEAVHLARDFGYVCETEFPARATAEYLCRQTEPDQLPTRRSMLLATKEICKEFVDLMSQDRSPLGASRPTPCLEPGVQSSLTHFSLLTHGFGTPALCAALSAFQSYLLEALKLLDKGENGGKNHHDKELKHRK", "length": 423 }, "evidence": [ { "id": "A0A8V0YL03", "url": "https://omabrowser.org/oma/group/A0A8V0YL03/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q6VUC0-1", "protein_name": "Transcription factor AP-2-epsilon", "gene_name": "TFAP2E", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLVHTYSAMERPDGLGAAAGGARLSSLPQAAYGPAPPLCHTPAATAAAEFQPPYFPPPYPQPPLPYGQAPDAAAAFPHLAGDPYGGLAPLAQPQPPQAAWAAPRAAARAHEEPPGLLAPPARALGLDPRRDYATAVPRLLHGLADGAHGLADAPLGLPGLAAAPGLEDLQAMDEPGMSLLDQSVIKKVPIPSKASSLSALSLAKDSLVGGITNPGEVFCSVPGRLSLLSSTSKYKVTVGEVQRRLSPPECLNASLLGGVLRRAKSKNGGRCLRERLEKIGLNLPAGRRKAANVTLLTSLVEGEAVHLARDFGYVCETEFPAKAAAEYLCRQHADPGELHSRKSMLLAAKQICKEFADLMAQDRSPLGNSRPALILEPGVQSCLTHFSLITHGFGGPAICAALTAFQNYLLESLKGLDKMFLSSVGSGHGETKASEKDAKHRK", "length": 442 }, "evidence": [ { "id": "A0A8V0YL03", "url": "https://omabrowser.org/oma/group/A0A8V0YL03/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q6VUP9-1", "protein_name": "Transcription factor AP-2-epsilon", "gene_name": "Tfap2e", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLVHTYSAMERPDGLGAAAGGTRLSSLPQAAYGPAPPLCHTPAASATADYHPPYFPPPYPQAPLPYGQGPDATAAFPHLAADPYGGLAPLAQPQPPQAAWAAPRAAARAHDEPPGLLAPPARALGLDPRRDYAAAVPRLLHSLADGAHGLADAPLGLPGLAEPPGLEELQAIDDPGMSLLDQSVIKKVPIPSKAGSLSTLALSKDSLVGGISNPSEVFCSVPGRLSLLSSTSKYKVTVGEVQRRLSPPECLNASLLGGVLRRAKSKNGGRCLRERLEKIGLNLPAGRRKAANVTLLTSLVEGEAVHLARDFGYVCETEFPAKAAAEYLCRQHADPGELHSRKSMLLAAKQICKEFADLMAQDRSPLGNSRPALILEPGVQSCLTHFSLITHGFGGPAICAALTAFQNYLLESLKGLEKMFLSGAGGGHGESKASEKDTKHRK", "length": 442 }, "evidence": [ { "id": "A0A8V0YL03", "url": "https://omabrowser.org/oma/group/A0A8V0YL03/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 6, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YL03", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL03" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YL03", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL03" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YL03", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL03" } ], "pmid": "" }, { "name": "RNA polymerase II transcription regulatory region sequence-specific DNA binding", "id": "GO:0000977", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000977", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YL03", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL03" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YL03", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL03" } ], "pmid": "" }, { "name": "DNA-binding transcription activator activity, RNA polymerase II-specific", "id": "GO:0001228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001228", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YL03", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL03" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YL03", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL03" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YL03", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL03" } ], "pmid": "" }, { "name": "regulation of cell population proliferation", "id": "GO:0042127", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042127", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YL03", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL03" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YL03", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL03" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 183, "end_pos": 185, "annotation": "n_glycosylation_sequon" }, { "start_pos": 240, "end_pos": 242, "annotation": "n_glycosylation_sequon" }, { "start_pos": 280, "end_pos": 282, "annotation": "n_glycosylation_sequon" }, { "start_pos": 31, "end_pos": 33, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YL03", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL03" }, { "id": "PF03299", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03299" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Transcription factor AP-2 C-terminal", "eco_id": "ECO_0000259", "start_pos": 206, "end_pos": 399, "start_aa": "Phe", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 183, "end_pos": 185 }, { "start_pos": 240, "end_pos": 242 }, { "start_pos": 280, "end_pos": 282 }, { "start_pos": 31, "end_pos": 33 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YLK2-1", "uniprot_ac": "A0A8V0YLK2", "uniprot_id": "A0A8V0YLK2_CHICK", "mass": { "chemical_mass": 65034.0, "monoisotopic_mass": 65034.0 }, "refseq": {}, "gene_names": [ { "name": "IL1R1", "type": "recommended", "evidence": [ { "id": "A0A8V0YLK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLK2" } ] } ], "protein_names": [ { "name": "Interleukin 1 receptor type 1", "type": "synonym", "evidence": [ { "id": "A0A8V0YLK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLK2/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLK2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLK2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "IL1R1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLK2", "locus": { "chromosome": "1", "start_pos": 133937543, "end_pos": 133914645, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013715", "url": "https://www.ensembl.org/id/ENSGALG00010013715" } ] } } ], "crossref": [ { "id": "A0A8V0YLK2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YLK2", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd05756", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05756", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd20994", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd20994", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000157", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000157", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003598", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003598", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004074", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004074", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004076", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004076", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015621", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015621", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035897", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035897", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YF71", "url": "https://www.orthodb.org/?gene=A0A8V0YF71", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YL23", "url": "https://www.orthodb.org/?gene=A0A8V0YL23", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YLK2", "url": "https://www.orthodb.org/?gene=A0A8V0YLK2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YLK7", "url": "https://www.orthodb.org/?gene=A0A8V0YLK7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11890", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11890", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11890:SF26", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11890:SF26", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01582", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01582", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-9020702", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9020702", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YF71", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF71", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YF71-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF71-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YL23", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL23", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YL23-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL23-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLK2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLK2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLK2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLK2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLK7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLK7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLK7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLK7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGIWILILLKNIQIKSISKFSFSLSLFFFSIEECVICNYFVLVGEPTAISCPVITLPMLHSDYNLTWYRNGSNMPITTERRARIHQRKGLLWFIPAALEDSGLYECEVRSLNRSKQKIINLKVFKNDNGLCFNGEMKYDQIVKSANAGKIICPDLENFKDEDNINPEIHWYKECKSGFLEDKRLVLAEGENAILILNVTIQDKGNYTCRMVYTYMGKQYNVSRTMNLEVKESPLKMRPEFIYPNNNTIEVELGSHVVMECNVSSGVYGLLPYWQVNDEDVDSFDSTYREQFYEEGMPHGIAVSGTKFNISEVKLKDYAYKFFCHFIYDSQEFTSYIKLEHPVQNIRGYLIGGGISLIFLLFLILIVYKIFKIDIVLWYRSSCHPLLGKKVSDGKIYDAYVLYPKNRESCLYSSDIFALKILPEVLERQCGYNLFIFGRNDLAGEAVIDVTDEKIHQSRRVIIILVPEPSCYGILEDASEKHLAVYNALIQDGIKIILIELEKIEDYANMPESIKYVKQKYGAIRWTGDFSERSHSASTRFWKKVRYHMPSRKHGSSSGFHLSS", "length": 563, "header": "tr|A0A8V0YLK2-1|A0A8V0YLK2_CHICK Isoform 1 of Interleukin 1 receptor type 1 OS=Gallus gallus OX=9031 GN=IL1R1 PE=3 SV=1 CANONICAL=A0A8V0YLK2-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YF71-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLK2/entry#A0A8V0YF71-1", "sequence": { "sequence": "MFTQPEGTEEIKPVVFQCFNECVICNYFVLVGEPTAISCPVITLPMLHSDYNLTWYRNGSNMPITTERRARIHQRKGLLWFIPAALEDSGLYECEVRSLNRSKQKIINLKVFKNDNGLCFNGEMKYDQIVKSANAGKIICPDLENFKDEDNINPEIHWYKECKSGFLEDKRLVLAEGENAILILNVTIQDKGNYTCRMVYTYMGKQYNVSRTMNLEVKESPLKMRPEFIYPNNNTIEVELGSHVVMECNVSSGVYGLLPYWQVNDEDVDSFDSTYREQFYEEGMPHGIAVSGTKFNISEVKLKDYAYKFFCHFIYDSQEFTSYIKLEHPVQNIRGYLIGGGISLIFLLFLILIVYKIFKIDIVLWYRSSCHPLLGKKVSDGKIYDAYVLYPKNRESCLYSSDIFALKILPEVLERQCGYNLFIFGRNDLAGEAVIDVTDEKIHQSRRVIIILVPEPSCYGILEDASEKHLAVYNALIQDGIKIILIELEKIEDYANMPESIKYVKQKYGAIRWTGDFSERSHSASTRFWKKVRYHMPSRKHGSSSGFHLSS", "length": 551, "header": "tr|A0A8V0YF71-1|A0A8V0YLK2_CHICK Computationally mapped isoform of Interleukin 1 receptor type 1 OS=Gallus gallus OX=9031 GN=IL1R1 PE=3 SV=1 CANONICAL=A0A8V0YLK2-1" }, "locus": { "chromosome": "1", "start_pos": 133934093, "end_pos": 133921254, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032940.1", "url": "https://www.ensembl.org/id/ENSGALT00010032940.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019484.1", "url": "https://www.ensembl.org/id/ENSGALP00010019484.1" } ] } }, { "isoform_ac": "A0A8V0YL23-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLK2/entry#A0A8V0YL23-1", "sequence": { "sequence": "MFTQPEGTEEIKPVVFQCFNEECVICNYFVLVGEPTAISCPVITLPMLHSDYNLTWYRNGSNMPITTERRARIHQRKGLLWFIPAALEDSGLYECEVRSLNRSKQKIINLKVFKNDNGLCFNGEMKYDQIVKSANAGKIICPDLENFKDEDNINPEIHWYKECKSGFLEDKRLVLAEGENAILILNVTIQDKGNYTCRMVYTYMGKQYNVSRTMNLEVKESPLKMRPEFIYPNNNTIEVELGSHVVMECNVSSGVYGLLPYWQVNDEDVDSFDSTYREQFYEEGMPHGIAVSGTKFNISEVKLKDYAYKFFCHFIYDSQEFTSYIKLEHPVQNIRGYLIGGGISLIFLLFLILIVYKIFKIDIVLWYRSSCHPLLGKKVSDGKIYDAYVLYPKNRESCLYSSDIFALKILPEVLERQCGYNLFIFGRNDLAGEAVIDVTDEKIHQSRRVIIILVPEPSCYGILEDASEKHLAVYNALIQDGIKIILIELEKIEDYANMPESIKYVKQKYGAIRWTGDFSERSHSASTRFWKKVRYHMPSRKHGSSSGFHLSS", "length": 552, "header": "tr|A0A8V0YL23-1|A0A8V0YL23_CHICK Computationally mapped isoform of Interleukin 1 receptor type 1 OS=Gallus gallus OX=9031 GN=IL1R1 PE=3 SV=1 CANONICAL=A0A8V0YLK2-1" }, "locus": { "chromosome": "1", "start_pos": 133934093, "end_pos": 133921254, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032948.1", "url": "https://www.ensembl.org/id/ENSGALT00010032948.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019488.1", "url": "https://www.ensembl.org/id/ENSGALP00010019488.1" } ] } }, { "isoform_ac": "A0A8V0YLK2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLK2/entry#A0A8V0YLK2-1", "sequence": { "sequence": "MGIWILILLKNIQIKSISKFSFSLSLFFFSIEECVICNYFVLVGEPTAISCPVITLPMLHSDYNLTWYRNGSNMPITTERRARIHQRKGLLWFIPAALEDSGLYECEVRSLNRSKQKIINLKVFKNDNGLCFNGEMKYDQIVKSANAGKIICPDLENFKDEDNINPEIHWYKECKSGFLEDKRLVLAEGENAILILNVTIQDKGNYTCRMVYTYMGKQYNVSRTMNLEVKESPLKMRPEFIYPNNNTIEVELGSHVVMECNVSSGVYGLLPYWQVNDEDVDSFDSTYREQFYEEGMPHGIAVSGTKFNISEVKLKDYAYKFFCHFIYDSQEFTSYIKLEHPVQNIRGYLIGGGISLIFLLFLILIVYKIFKIDIVLWYRSSCHPLLGKKVSDGKIYDAYVLYPKNRESCLYSSDIFALKILPEVLERQCGYNLFIFGRNDLAGEAVIDVTDEKIHQSRRVIIILVPEPSCYGILEDASEKHLAVYNALIQDGIKIILIELEKIEDYANMPESIKYVKQKYGAIRWTGDFSERSHSASTRFWKKVRYHMPSRKHGSSSGFHLSS", "length": 563, "header": "tr|A0A8V0YLK2-1|A0A8V0YLK2_CHICK Isoform 1 of Interleukin 1 receptor type 1 OS=Gallus gallus OX=9031 GN=IL1R1 PE=3 SV=1 CANONICAL=A0A8V0YLK2-1" }, "locus": { "chromosome": "1", "start_pos": 133934093, "end_pos": 133921349, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032945.1", "url": "https://www.ensembl.org/id/ENSGALT00010032945.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019486.1", "url": "https://www.ensembl.org/id/ENSGALP00010019486.1" } ] } }, { "isoform_ac": "A0A8V0YLK7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLK2/entry#A0A8V0YLK7-1", "sequence": { "sequence": "IKFSFSLSLFFFSIEECVICNYFVLVGEPTAISCPVITLPMLHSDYNLTWYRNGSNMPITTERRARIHQRKGLLWFIPAALEDSGLYECEVRSLNRSKQKIINLKVFKNDNGLCFNGEMKYDQIVKSANAGKIICPDLENFKDEDNINPEIHWYKECKSGFLEDKRLVLAEGENAILILNVTIQDKGNYTCRMVYTYMGKQYNVSRTMNLEVKESPLKMRPEFIYPNNNTIEVELGSHVVMECNVSSGVYGLLPYWQVNDEDVDSFDSTYREQFYEEGMPHGIAVSGTKFNISEVKLKDYAYKFFCHFIYDSQEFTSYIKLEHPVQNIRGYLIGGGISLIFLLFLILIVYKIFKIDIVLWYRSSCHPLLGKKVSDGKIYDAYVLYPKNRESCLYSSDIFALKILPEVLERQCGYNLFIFGRNDLAGEAVIDVTDEKIHQSRRVIIILVPEPSCYGILEDASEKHLAVYNALIQDGIKIILIELEKIEDYANMPESIKYVKQKYGAIRWTGDFSERSHSASTRFWKKVRYHMPSRKHGSSSGFHLSS", "length": 546, "header": "tr|A0A8V0YLK7-1|A0A8V0YLK7_CHICK Computationally mapped isoform of Interleukin 1 receptor type 1 OS=Gallus gallus OX=9031 GN=IL1R1 PE=3 SV=1 CANONICAL=A0A8V0YLK2-1" }, "locus": { "chromosome": "1", "start_pos": 133934093, "end_pos": 133920682, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032955.1", "url": "https://www.ensembl.org/id/ENSGALT00010032955.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019491.1", "url": "https://www.ensembl.org/id/ENSGALP00010019491.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-9020702", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9020702", "resource": "Reactome", "description": "Interleukin-1 signaling" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "inflammatory response", "id": "GO:0006954", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006954", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLK2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLK2" } ], "pmid": "" }, { "name": "cell surface receptor signaling pathway", "id": "GO:0007166", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007166", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLK2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLK2" } ], "pmid": "" }, { "name": "regulation of inflammatory response", "id": "GO:0050727", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050727", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLK2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLK2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLK2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLK2" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLK2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLK2" } ], "pmid": "" }, { "name": "cell surface", "id": "GO:0009986", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009986", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLK2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLK2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLK2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLK2" } ], "pmid": "" }, { "name": "interleukin-1, type I, activating receptor activity", "id": "GO:0004909", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004909", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLK2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLK2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 112, "end_pos": 114, "annotation": "n_glycosylation_sequon" }, { "start_pos": 197, "end_pos": 199, "annotation": "n_glycosylation_sequon" }, { "start_pos": 205, "end_pos": 207, "annotation": "n_glycosylation_sequon" }, { "start_pos": 220, "end_pos": 222, "annotation": "n_glycosylation_sequon" }, { "start_pos": 245, "end_pos": 247, "annotation": "n_glycosylation_sequon" }, { "start_pos": 261, "end_pos": 263, "annotation": "n_glycosylation_sequon" }, { "start_pos": 308, "end_pos": 310, "annotation": "n_glycosylation_sequon" }, { "start_pos": 64, "end_pos": 66, "annotation": "n_glycosylation_sequon" }, { "start_pos": 70, "end_pos": 72, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YLK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLK2" }, { "id": "PS50835", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50835" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ig-like", "eco_id": "ECO_0000259", "start_pos": 44, "end_pos": 120, "start_aa": "Gly", "end_aa": "Asn", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0YLK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLK2" }, { "id": "PS50104", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50104" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "TIR", "eco_id": "ECO_0000259", "start_pos": 394, "end_pos": 548, "start_aa": "Lys", "end_aa": "Met", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 112, "end_pos": 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{ "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YIQ9-1", "uniprot_ac": "A0A8V0YIQ9", "uniprot_id": "A0A8V0YIQ9_CHICK", "mass": { "chemical_mass": 22647.0, "monoisotopic_mass": 22647.0 }, "refseq": {}, "gene_names": [ { "name": "THEMIS2", "type": "recommended", "evidence": [ { "id": "A0A8V0YIQ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIQ9" } ] } ], "protein_names": [ { "name": "Thymocyte selection associated family member 2", "type": "synonym", "evidence": [ { "id": "A0A8V0YIQ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIQ9/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIQ9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIQ9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "THEMIS2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIQ9", "locus": {} } ], "crossref": [ { "id": "A0A8V0YIQ9", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YIQ9", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR025946", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025946", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039671", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039671", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YFN0", "url": "https://www.orthodb.org/?gene=A0A8V0YFN0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YGP8", "url": "https://www.orthodb.org/?gene=A0A8V0YGP8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YIQ9", "url": "https://www.orthodb.org/?gene=A0A8V0YIQ9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15215", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15215", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15215:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15215:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF12736", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12736", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YFN0", "url": 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"MEPLSFQEYICSLDPATLPRILRICSGVYFQGSVYEISGNECCLSTGDLLKVTAVTLQKVICEDVQTGQKTELPPTFKVRRDQVRIPSTLEVDVEDVTEESQDVHFAQPLLLSELLGMEEVLPAQAEILEGPHGAAIFESSWASRLQKGQRLQIHGCSHTWRVLASARSSARRFLLSSSYQGRFRRRPRQFAGVQELAAGLQP", "length": 203, "header": "tr|A0A8V0YIQ9-1|A0A8V0YIQ9_CHICK Isoform 1 of Thymocyte selection associated family member 2 OS=Gallus gallus OX=9031 GN=THEMIS2 PE=3 SV=1 CANONICAL=A0A8V0YIQ9-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YFN0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIQ9/entry#A0A8V0YFN0-1", "sequence": { "sequence": "MEPLSFQEYICSLDPATLPRILRICSGVYFQGSVYEISGNECCLSTGDLLKVTAVTLQKVICEDVQTGQKTELPPTFKGLFQPSPATSPCPTPQGPSLQGSRQKGLTLHQALGQSSRQTQPLLCPSISPHALLLSPVYEAQATMHWTR", "length": 148, "header": "tr|A0A8V0YFN0-1|A0A8V0YIQ9_CHICK Computationally mapped isoform of Thymocyte selection associated family member 2 OS=Gallus gallus OX=9031 GN=THEMIS2 PE=3 SV=1 CANONICAL=A0A8V0YIQ9-1" }, "locus": { "chromosome": "23", "start_pos": 1828526, "end_pos": 1826608, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030505.1", "url": "https://www.ensembl.org/id/ENSGALT00010030505.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017688.1", "url": "https://www.ensembl.org/id/ENSGALP00010017688.1" } ] } }, { "isoform_ac": "A0A8V0YGP8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIQ9/entry#A0A8V0YGP8-1", "sequence": { "sequence": "MEPLSFQEYICSLDPATLPRILRICSGVYFQGSVYEISGNECCLSTGDLLKVTAVTLQKVICEDVQTGQKTELPPTFKGLFQPSPATSPCPTPQGPSLQGSRQKGLTLHQALGQSSRQTQPLLCPSISPHALLLSPVYEAQATMHYVKRSDDEHDYETIEGNIQKTIRKVQAILPF", "length": 176, "header": "tr|A0A8V0YGP8-1|A0A8V0YIQ9_CHICK Computationally mapped isoform of Thymocyte selection associated family member 2 OS=Gallus gallus OX=9031 GN=THEMIS2 PE=3 SV=1 CANONICAL=A0A8V0YIQ9-1" }, "locus": { "chromosome": "23", "start_pos": 1830342, "end_pos": 1826608, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030514.1", "url": "https://www.ensembl.org/id/ENSGALT00010030514.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017696.1", "url": "https://www.ensembl.org/id/ENSGALP00010017696.1" } ] } }, { "isoform_ac": "A0A8V0YIQ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIQ9/entry#A0A8V0YIQ9-1", "sequence": { "sequence": "MEPLSFQEYICSLDPATLPRILRICSGVYFQGSVYEISGNECCLSTGDLLKVTAVTLQKVICEDVQTGQKTELPPTFKVRRDQVRIPSTLEVDVEDVTEESQDVHFAQPLLLSELLGMEEVLPAQAEILEGPHGAAIFESSWASRLQKGQRLQIHGCSHTWRVLASARSSARRFLLSSSYQGRFRRRPRQFAGVQELAAGLQP", "length": 203, "header": "tr|A0A8V0YIQ9-1|A0A8V0YIQ9_CHICK Isoform 1 of Thymocyte selection associated family member 2 OS=Gallus gallus OX=9031 GN=THEMIS2 PE=3 SV=1 CANONICAL=A0A8V0YIQ9-1" }, "locus": { "chromosome": "23", "start_pos": 1828885, "end_pos": 1826608, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030509.1", "url": "https://www.ensembl.org/id/ENSGALT00010030509.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017692.1", "url": "https://www.ensembl.org/id/ENSGALP00010017692.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YIQ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIQ9" }, { "id": "PF12736", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12736" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CABIT", "eco_id": "ECO_0000259", "start_pos": 18, "end_pos": 78, "start_aa": "Leu", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YM62-1", "uniprot_ac": "A0A8V0YM62", "uniprot_id": "A0A8V0YM62_CHICK", "mass": { "chemical_mass": 33452.0, "monoisotopic_mass": 33452.0 }, "refseq": { "ac": "XP_003643032", "name": "cyclin-O", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003643032" }, "gene_names": [ { "name": "CCNO", "type": "recommended", "evidence": [ { "id": "A0A8V0YM62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM62" } ] }, { "name": "CCNO", "type": "synonym", "evidence": [ { "id": "XP_003643032", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003643032" } ] } ], "protein_names": [ { "name": "Cyclin O", "type": "synonym", "evidence": [ { "id": "A0A8V0YM62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM62/entry#names_and_taxonomy" } ] }, { "name": "cyclin-O", "type": "synonym", "evidence": [ { "id": "XP_003643032", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003643032" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052572.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_003643032.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003643032", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003643032" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YM62", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM62" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CCNO", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM62", "locus": { "chromosome": "Z", "start_pos": 17272979, "end_pos": 17274317, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013928", "url": "https://www.ensembl.org/id/ENSGALG00010013928" } ] } } ], "crossref": [ { "id": "A0A8V0YM62", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YM62", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd20536", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd20536", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd20722", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd20722", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100857393", "url": "https://www.ncbi.nlm.nih.gov/gene/100857393", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004367", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004367", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006671", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006671", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013763", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013763", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036915", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036915", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039361", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039361", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:100857393", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100857393", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "RNCLARQ", "url": "https://omabrowser.org/oma/group/RNCLARQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YFS1", "url": "https://www.orthodb.org/?gene=A0A8V0YFS1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YM62", "url": "https://www.orthodb.org/?gene=A0A8V0YM62", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10177", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10177", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00134", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00134", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02984", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02984", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003643032", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003643032", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YFS1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFS1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YFS1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFS1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YM62", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM62", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YM62-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM62-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVAATAERREATPQGPESGPGPGRCPGHLKRRRQRREEKPTSGESLLELQTFREYGESWYRSRKGLESRFQPREPLARQPQVTAEARCRLVSWLIPVHRDLGYSFEALCLTVNILDRFLATTPVAADCFQLLGVTALLLACKQVEVHPPSVKQLLALCCGAFSGQQLCNLECIVLHKLGFSLGAPTVSFFLEHFTRVRLEAPGADPGEAADAGSLARGVAEISLADYAFTKYPPSLLAVASVGLADRLLQHRCPLDLRLSGYRRTRLRDCMAELRLLVSLNAAALPLVLPAEVARKCPWLRGGD", "length": 304, "header": "tr|A0A8V0YM62-1|A0A8V0YM62_CHICK Isoform 1 of Cyclin O OS=Gallus gallus OX=9031 GN=CCNO PE=3 SV=1 CANONICAL=A0A8V0YM62-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YFS1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM62/entry#A0A8V0YFS1-1", "sequence": { "sequence": "NGGGSGERRSRRAGRASWSCRPSASTGRAGTAPARGWRAASSRGSRSPGSRDGGGALPAGQLAHPRAPRPGVLLRGALPDRQHPRPLPRYHPGGRRLLPAARGDGAAPGLQTGTAERVRAGCPRAPAAPLLAPSLPPQVEVHPPSVKQLLALCCGAFSGQQLCNLECIVLHKLGFSLGAPTVSFFLEHFTRVRLEAPGADPGEAADAGSLARGVAEISLADYAFTKYPPSLLAVASVGLADRLLQHRCPLDLRLSGYRRTRLRDCMAELRLLVSLNAAALPLVLPAEVARKCPWLRGGD", "length": 299, "header": "tr|A0A8V0YFS1-1|A0A8V0YM62_CHICK Computationally mapped isoform of Cyclin O OS=Gallus gallus OX=9031 GN=CCNO PE=3 SV=1 CANONICAL=A0A8V0YM62-1" }, "locus": { "chromosome": "Z", "start_pos": 17274202, "end_pos": 17273230, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033385.1", "url": "https://www.ensembl.org/id/ENSGALT00010033385.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019694.1", "url": "https://www.ensembl.org/id/ENSGALP00010019694.1" } ] } }, { "isoform_ac": "A0A8V0YM62-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM62/entry#A0A8V0YM62-1", "sequence": { "sequence": "MVAATAERREATPQGPESGPGPGRCPGHLKRRRQRREEKPTSGESLLELQTFREYGESWYRSRKGLESRFQPREPLARQPQVTAEARCRLVSWLIPVHRDLGYSFEALCLTVNILDRFLATTPVAADCFQLLGVTALLLACKQVEVHPPSVKQLLALCCGAFSGQQLCNLECIVLHKLGFSLGAPTVSFFLEHFTRVRLEAPGADPGEAADAGSLARGVAEISLADYAFTKYPPSLLAVASVGLADRLLQHRCPLDLRLSGYRRTRLRDCMAELRLLVSLNAAALPLVLPAEVARKCPWLRGGD", "length": 304, "header": "tr|A0A8V0YM62-1|A0A8V0YM62_CHICK Isoform 1 of Cyclin O OS=Gallus gallus OX=9031 GN=CCNO PE=3 SV=1 CANONICAL=A0A8V0YM62-1" }, "locus": { "chromosome": "Z", "start_pos": 17274290, "end_pos": 17273230, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033391.1", "url": "https://www.ensembl.org/id/ENSGALT00010033391.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019697.1", "url": "https://www.ensembl.org/id/ENSGALP00010019697.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:100857393", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100857393", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "multi-ciliated epithelial cell differentiation", "id": "GO:1903251", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903251", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YM62", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM62" } ], "pmid": "" }, { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YM62", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM62" } ], "pmid": "" }, { "name": "cilium assembly", "id": "GO:0060271", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060271", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YM62", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM62" } ], "pmid": "" }, { "name": "G1/S transition of mitotic cell cycle", "id": "GO:0000082", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000082", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YM62", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM62" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YM62", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM62" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YM62", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM62" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YM62", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM62" } ], "pmid": "" }, { "name": "microtubule organizing center", "id": "GO:0005815", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005815", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YM62", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM62" } ], "pmid": "" }, { "name": "cyclin-dependent protein kinase holoenzyme complex", "id": "GO:0000307", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000307", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YM62", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM62" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "cyclin-dependent protein serine/threonine kinase regulator activity", "id": "GO:0016538", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016538", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YM62", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM62" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YM62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM62" }, { "id": "SM01332", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM01332" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Cyclin C-terminal", "eco_id": "ECO_0000259", "start_pos": 185, "end_pos": 298, "start_aa": "Pro", "end_aa": "Pro", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0YM62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM62" }, { "id": "SM00385", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00385" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Cyclin-like", "eco_id": "ECO_0000259", "start_pos": 92, "end_pos": 176, "start_aa": "Ser", "end_aa": "His", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YIZ6-1", "uniprot_ac": "A0A8V0YIZ6", "uniprot_id": "A0A8V0YIZ6_CHICK", "mass": { "chemical_mass": 92252.0, "monoisotopic_mass": 92252.0 }, "refseq": { "ac": "XP_004938019", "name": "epidermal growth factor receptor kinase substrate 8 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004938019" }, "gene_names": [ { "name": "EPS8", "type": "recommended", "evidence": [ { "id": "A0A8V0YIZ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIZ6" } ] }, { "name": "EPS8", "type": "synonym", "evidence": [ { "id": "XP_004938019", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004938019" } ] } ], "protein_names": [ { "name": "Epidermal growth factor receptor kinase substrate 8", "type": "recommended", "evidence": [ { "id": "A0A8V0YIZ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIZ6/entry#names_and_taxonomy" } ] }, { "name": "epidermal growth factor receptor kinase substrate 8 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_004938019", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004938019" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_004938019.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004938019", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004938019" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIZ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIZ6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "EPS8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIZ6", "locus": { "chromosome": "1", "start_pos": 62993338, "end_pos": 63124660, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012768", "url": "https://www.ensembl.org/id/ENSGALG00010012768" } ] } } ], "crossref": [ { "id": "A0A8V0YIZ6", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YIZ6", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd01210", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01210", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd09540", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09540", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd11764", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11764", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "418174", "url": "https://www.ncbi.nlm.nih.gov/gene/418174", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006020", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006020", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013625", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013625", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013761", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013761", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033928", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033928", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035462", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035462", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036028", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036028", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039801", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039801", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041418", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041418", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055093", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055093", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:418174", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418174", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "NKNWWEC", "url": "https://omabrowser.org/oma/group/NKNWWEC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YAK0", "url": "https://www.orthodb.org/?gene=A0A8V0YAK0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YAK5", "url": "https://www.orthodb.org/?gene=A0A8V0YAK5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YFU5", "url": "https://www.orthodb.org/?gene=A0A8V0YFU5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": 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"database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF18016", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18016", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF22975", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22975", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_004938019", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004938019", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YAK0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAK0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YAK0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAK0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YAK5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAK5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YAK5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAK5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YFU5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFU5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YFU5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFU5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YFV0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFV0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YFV0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFV0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YGX8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGX8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YGX8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGX8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YIZ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIZ6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YIZ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIZ6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNGHISNTPPGGYGSYSPQINGYGSPTFAQSEREQNSRTSAKALYEQRKNYARDSASSISETSQYHVEHLTTFVLDRKEAMITVDDGIRKLKLLDAKGKVWTQDMILQVDDKAVSLVDLESKNELENFPLSTIQHCQAVMNACNYNSILALVCKEPTQNKPDLHLFQCDEIKASFIHEDIESAISDSKSGKQKKRLETLRMISSADGAIPPPPRAPAPVPPGTVTQVDVRSRVAAWSAWAAEQGDYEKHRQYPDHEETAEMIAARIDRDVQILNHILDDIEYFVTKLQKAAEAFAELSKRKKTKKSKKKGPGEGVLTLRSKPPPPDEFVDCFQKFKHGFNLLAKLKFHIQNPSAAELVHFLFTPLHMVVQTTGGPELASTVLSPLLTKDTIDFLQYTVTSEEGQLWMSLGDTWTKARADWPKDQFIPPYVPRFRNGWEPPLLNFMGAPNEQELNNLAESVANFAEQQRKQEIKRLSTEPPSVPDYPPADGYAFSNTVYKRGPLLDQGAAVAAFKQTVSRHVDRNYEAHNKTQSKKYAKCKYEFMARNNSELSVLKEEIVEILDDRKQWWKVRNKSGNTGFVPNNILDPLRNYEGGLGLPEPVYTRAIQKQRTDYVAKQPDPVPATPSPPPMPAPVPAAVPLPPSTPAPIPVPVPKAPATVSRQSSTSSDSGGSVARDSQKHKQAPVDRRKSQMEEVQDELVHRLTIGRSNAQRKFHVPRPNIPVVNITYDSSPEDVKAWLQSKGFNPVTVNSLGVLTGAQLFSLNKEELRTVCPEGSRVYSQITVQKSALEANSGSSELQEIMRRRQEKISAAASDSGVESFDEGSSH", "length": 828, "header": "tr|A0A8V0YIZ6-1|A0A8V0YIZ6_CHICK Isoform 1 of Epidermal growth factor receptor kinase substrate 8 OS=Gallus gallus OX=9031 GN=EPS8 PE=1 SV=1 CANONICAL=A0A8V0YIZ6-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YAK0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIZ6/entry#A0A8V0YAK0-1", "sequence": { "sequence": "MNGHISNTPPGGYGSYSPQINGYGSPTFAQSEREQNSRTSAKALYEQRKNYARDSASSISETSQYHHLTTFVLDRKEAMITVDDGIRKLKLLDAKGKVWTQDMILQVDDKAVSLVDLESKNELENFPLSTIQHCQAVMNACNYNSILALVCKEPTQNKPDLHLFQCDEIKASFIHEDIESAISDSKSGKQKKRLETLRMISSADGAIPPPPRAPAPVPPGTVTQVDVRSRVAAWSAWAAEQGDYEKHRQYPDHEETAEMIAARIDRDVQILNHILDDIEYFVTKLQKAAEAFAELSKRKKTKKSKKKGPGEGVLTLRSKPPPPDEFVDCFQKFKHGFNLLAKLKFHIQNPSAAELVHFLFTPLHMVVQTTGGPELASTVLSPLLTKDTIDFLQYTVTSEEGQLWMSLGDTWTKARADWPKDQFIPPYVPRFRNGWEPPLLNFMGAPNEQELNNLAESVANFAEQQRKQEIKRLSTEPPSVPDYPPADGYAFSNTVYKRGPLLDQGAAVAAFKQTVSRHVDRNYEAHNKTQSKKYAKCKYEFMARNNSELSVLKEEIVEILDDRKQWWKVRNKSGNTGFVPNNILDPLRNYEGGLGLPEPVYTRAIQKQRTDYVAKQPDPVPATPSPPPMPAPVPAAVPLPPSTPAPIPVPVPKAPATVSRQSSTSSDSGGSVARDSQKHKQAPVDRRKSQMEEVQDELVHRLTIGRSNAQRKFHVPRPNIPVVNITYDSSPEDVKAWLQSKGFNPVTVNSLGVLTGAQLFSLNKEELRTVCPEGSRVYSQITVQKSALEANSGSSELQEIMRRRQEKISAAASDSGVESFDEGSSH", "length": 826, "header": "tr|A0A8V0YAK0-1|A0A8V0YAK0_CHICK Computationally mapped isoform of Epidermal growth factor receptor kinase substrate 8 OS=Gallus gallus OX=9031 GN=EPS8 PE=1 SV=1 CANONICAL=A0A8V0YIZ6-1" }, "locus": { "chromosome": "1", "start_pos": 63048133, "end_pos": 62994638, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030630.1", "url": "https://www.ensembl.org/id/ENSGALT00010030630.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017765.1", "url": "https://www.ensembl.org/id/ENSGALP00010017765.1" } ] } }, { "isoform_ac": "A0A8V0YAK5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIZ6/entry#A0A8V0YAK5-1", "sequence": { "sequence": "MNGHISNTPPGGYGSYSPQINGYGSPTFAQSEREQNSRTSAKALYEQRKNYARDSASSISETSQYHVEHLTTFVLDRKEAMITVDDGIRKLKLLDAKGKVWTQDMILQVDDKAVSLVDLESKNELENFPLSTIQHCQAVMNACNYNSILALVCKEPTQNKPDLHLFQCDEIKASFIHEDIESAISDSKSGKQKKRLETLRMISSADGAIPPPPRAPAPVPPGTVTQVDVRSRVAAWSAWAAEQGDYEKHRQYPDHEETAEMIAARIDRDVQILNHILDDIEYFVTKLQKAAEAFAELSKRKKTKKSKKKGPGEGVLTLRSKPPPPDEFVDCFQKFKHGFNLLAKLKFHIQNPSAAELVHFLFTPLHMVVQTTGGPELASTVLSPLLTKDTIDFLQYTVTSEEGQLWMSLGDTWTKARADWPKDQFIPPYVPRFRNGWEPPLLNFMGAPNEQELNNLAESVANFAEQQRKQEIKRLSTEPPSVPDYPPADGYAFSNTVYKRGPLLDQGAAVAAFKQTVSRHVDRNYEAHNKTQSKKYAKCKYEFMARNNSELSVLKEEIVEILDDRKQWWKVRNKSGNTGFVPNNILDPLRNYEGGLGLPEPVYTRAIQKQRTDYVAKQPDPVPATPSPPPMPAPVPAAVPLPPSTPAPIPVPVPKAPATVSRQSSTSSDSGGSVARDSQKHKQAPVDRRKSQMEEVQDELVHRLTIGRSNAQRKFHVPRPNIPVVNITYDSSPEDVKAWLQSKGFNPVTVNSLGVLTGAQLFSLNKEELRTVCPEGSRVYSQITVQKSALEFRTARNYEKTARKNQCSCIRFRCGVF", "length": 817, "header": "tr|A0A8V0YAK5-1|A0A8V0YAK5_CHICK Computationally mapped isoform of Epidermal growth factor receptor kinase substrate 8 OS=Gallus gallus OX=9031 GN=EPS8 PE=1 SV=1 CANONICAL=A0A8V0YIZ6-1" }, "locus": { "chromosome": "1", "start_pos": 63048133, "end_pos": 62994657, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030652.1", "url": "https://www.ensembl.org/id/ENSGALT00010030652.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017771.1", "url": "https://www.ensembl.org/id/ENSGALP00010017771.1" } ] } }, { "isoform_ac": "A0A8V0YFU5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIZ6/entry#A0A8V0YFU5-1", "sequence": { "sequence": "MNGHISNTPPGGYGSYSPQINGYGSPTFAQSEREQNSRTSAKALYEQRKNYARDSASSISETSQYHVEHLTTFVLDRKEAMITVDDGIRKLKLLDAKGKVWTQDMILQVDDKAVSLVDLESKNELENFPLSTIQHCQAVMNACNYNSILALVCKEPTQNKPDLHLFQCDEIKASFIHEDIESAISDSKSGKQKKRLETLRMISSADGAIPPPPRAPAPVPPGTVTQVDVRSRVAAWSAWAAEQGDYEKHRQYPDHEETAEMIAARIDRDVQILNHILDDIEYFVTKLQKAAEAFAELSKRKKTKKSKKKGPGEGVLTLRSKPPPPDEFVDCFQKFKHGFNLLAKLKFHIQNPSAAELVHFLFTPLHMVVQTTGGPELASTVLSPLLTKDTIDFLQYTVTSEEGQLWMSLGDTWTKARADWPKDQFIPPYVPRFRNGWEPPLLNFMGAPNEQELNNLAESVANFAEQQRKQEIKRLSTEPPSVPDYPPADGNYEAHNKTQSKKYAKCKYEFMARNNSELSVLKEEIVEILDDRKQWWKVRNKSGNTGFVPNNILDPLRNYEGGLGLPEPVYTRAIQKQRTDYVAKQPDPVPATPSPPPMPAPVPAAVPLPPSTPAPIPVPVPKAPATVSRQSSTSSDSGGSVARDSQKHKQAPVDRRKSQMEEVQDELVHRLTIGRSNAQRKFHVPRPNIPVVNITYDSSPEDVKAWLQSKGFNPVTVNSLGVLTGAQLFSLNKEELRTVCPEGSRVYSQITVQKSALEANSGSSELQEIMRRRQEKISAAASDSGVESFDEGSSH", "length": 795, "header": "tr|A0A8V0YFU5-1|A0A8V0YIZ6_CHICK Computationally mapped isoform of Epidermal growth factor receptor kinase substrate 8 OS=Gallus gallus OX=9031 GN=EPS8 PE=1 SV=1 CANONICAL=A0A8V0YIZ6-1" }, "locus": { "chromosome": "1", "start_pos": 63048133, "end_pos": 62994638, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030593.1", "url": "https://www.ensembl.org/id/ENSGALT00010030593.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017749.1", "url": "https://www.ensembl.org/id/ENSGALP00010017749.1" } ] } }, { "isoform_ac": "A0A8V0YFV0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIZ6/entry#A0A8V0YFV0-1", "sequence": { "sequence": "MNGHISNTPPGGYGSYSPQINGYGSPTFAQSEREQNSRTSAKALYEQRKNYARDSASSISETSQYHVEHLTTFVLDRKEAMITVDDGIRKLKLLDAKGKVWTQDMILQVDDKAVSLVDLESKNELENFPLSTIQHCQAVMNACNYNSILALVCKEPTQNKPDLHLFQCDEIKASFIHEDIESAISDSKSGKQKKRLETLRMISSADGAIPPPPRAPAPVPPGTVTQVDVRSRVAAWSAWAAEQGDYEKHRQYPDHEETAEMIAARIDRDVQILNHILDDIEYFVTKLQKAAEAFAELSKRKKTKKSKKKGPGEGVLTLRSKPPPPDEFVDCFQKFKHGFNLLAKLKFHIQNPSAAELVHFLFTPLHMVVQTTGGPELASTVLSPLLTKDTIDFLQYTVTSEEGQLWMSLGDTWTKARADWPKDQFIPPYVPRFRNGWEPPLLNFMGAPNEQELNNLAESVANFAEQQRKQEIKRLSTEPPSVPDYPPADGYAFSNTVYKRGPLLDQGAAVAAFKQTVSRHVDRNYEAHNKTQSKKYAKCKYEFMARNNSELSVLKEEIVEILDDRKQWWKVRNKSGNTGFVPNNILDPLRNYEGGLGLPEPVYTRAIQKQRTDYVAKQPDPVPATPSPPPMPAPVPAAVPLPPSTPAPIPVPVPKAPATVSRQSSTSSDSGGSVARDSQKHKQAPVDRRKSQMEEVQDELVHRLTIGRSNAQRKFHVPRPNIPVVNITYDSSPEDVKAWLQSKGFNPVTVNSLGVLTGAQLFSLNKEELRTVCPEGSRVYSQITANSGSSELQEIMRRRQEKISAAASDSGVESFDEGSSH", "length": 821, "header": "tr|A0A8V0YFV0-1|A0A8V0YIZ6_CHICK Computationally mapped isoform of Epidermal growth factor receptor kinase substrate 8 OS=Gallus gallus OX=9031 GN=EPS8 PE=1 SV=1 CANONICAL=A0A8V0YIZ6-1" }, "locus": { "chromosome": "1", "start_pos": 63048133, "end_pos": 62994638, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030604.1", "url": "https://www.ensembl.org/id/ENSGALT00010030604.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017754.1", "url": "https://www.ensembl.org/id/ENSGALP00010017754.1" } ] } }, { "isoform_ac": "A0A8V0YGX8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIZ6/entry#A0A8V0YGX8-1", "sequence": { "sequence": "MNGHISNTPPGGYGSYSPQINGYGSPTFAQSEREQNSRTSAKALYEQRKNYARDSASSISETSQYHVEHLTTFVLDRKEAMITVDDGIRKLKLLDAKGKVWTQDMILQVDDKAVSLVDLESKNELENFPLSTIQHCQAVMNACNYNSILALVCKEPTQNKPDLHLFQCDEIKASFIHEDIESAISDSKSGKQKKRLETLRMISSADGAIPPPPRAPAPVPPGTVTQVDVRSRVAAWSAWAAEQGDYEKHRQYPDHEETAEMIAARIDRDVQILNHILDDIEYFVTKLQKAAEAFAELSKRKKTKKSKKKGPGEGVLTLRSKPPPPDEFVDCFQKFKHGFNLLAKLKFHIQNPSAAELVHFLFTPLHMVVQTTGGPELASTVLSPLLTKDTIDFLQYTVTSEEGQLWMSLGDTWTKARADWPKDQFIPPYVPRFRNGWEPPLLNFMGAPNEQELNNLAESVANFAEQQRKQEIKRLSTEPPSVPDYPPADGYAFSNTVYKRGPLLDQGAAVAAFKQTVSRHVDRNYEAHNKTQSKKYAKCKYEFMARNNSELSVLKEEIVEILDDRKQWWKVRNKSGNTGFVPNNILDPLRNYEGGLGLPEPVYTRAIQLLMPKKEFELFKKQRTDYVAKQPDPVPATPSPPPMPAPVPAAVPLPPSTPAPIPVPVPKAPATVSRQSSTSSDSGGSVARDSQKHKQAPVDRRKSQMEEVQDELVHRLTIGRSNAQRKFHVPRPNIPVVNITYDSSPEDVKAWLQSKGFNPVTVNSLGVLTGAQLFSLNKEELRTVCPEGSRVYSQITVQKSALEANSGSSELQEIMRRRQEKISAAASDSGVESFDEGSSH", "length": 840, "header": "tr|A0A8V0YGX8-1|A0A8V0YIZ6_CHICK Computationally mapped isoform of Epidermal growth factor receptor kinase substrate 8 OS=Gallus gallus OX=9031 GN=EPS8 PE=1 SV=1 CANONICAL=A0A8V0YIZ6-1" }, "locus": { "chromosome": "1", "start_pos": 63048133, "end_pos": 62994638, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030664.1", "url": "https://www.ensembl.org/id/ENSGALT00010030664.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017779.1", "url": "https://www.ensembl.org/id/ENSGALP00010017779.1" } ] } }, { "isoform_ac": "A0A8V0YIZ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIZ6/entry#A0A8V0YIZ6-1", "sequence": { "sequence": "MNGHISNTPPGGYGSYSPQINGYGSPTFAQSEREQNSRTSAKALYEQRKNYARDSASSISETSQYHVEHLTTFVLDRKEAMITVDDGIRKLKLLDAKGKVWTQDMILQVDDKAVSLVDLESKNELENFPLSTIQHCQAVMNACNYNSILALVCKEPTQNKPDLHLFQCDEIKASFIHEDIESAISDSKSGKQKKRLETLRMISSADGAIPPPPRAPAPVPPGTVTQVDVRSRVAAWSAWAAEQGDYEKHRQYPDHEETAEMIAARIDRDVQILNHILDDIEYFVTKLQKAAEAFAELSKRKKTKKSKKKGPGEGVLTLRSKPPPPDEFVDCFQKFKHGFNLLAKLKFHIQNPSAAELVHFLFTPLHMVVQTTGGPELASTVLSPLLTKDTIDFLQYTVTSEEGQLWMSLGDTWTKARADWPKDQFIPPYVPRFRNGWEPPLLNFMGAPNEQELNNLAESVANFAEQQRKQEIKRLSTEPPSVPDYPPADGYAFSNTVYKRGPLLDQGAAVAAFKQTVSRHVDRNYEAHNKTQSKKYAKCKYEFMARNNSELSVLKEEIVEILDDRKQWWKVRNKSGNTGFVPNNILDPLRNYEGGLGLPEPVYTRAIQKQRTDYVAKQPDPVPATPSPPPMPAPVPAAVPLPPSTPAPIPVPVPKAPATVSRQSSTSSDSGGSVARDSQKHKQAPVDRRKSQMEEVQDELVHRLTIGRSNAQRKFHVPRPNIPVVNITYDSSPEDVKAWLQSKGFNPVTVNSLGVLTGAQLFSLNKEELRTVCPEGSRVYSQITVQKSALEANSGSSELQEIMRRRQEKISAAASDSGVESFDEGSSH", "length": 828, "header": "tr|A0A8V0YIZ6-1|A0A8V0YIZ6_CHICK Isoform 1 of Epidermal growth factor receptor kinase substrate 8 OS=Gallus gallus OX=9031 GN=EPS8 PE=1 SV=1 CANONICAL=A0A8V0YIZ6-1" }, "locus": { "chromosome": "1", "start_pos": 63048133, "end_pos": 62994638, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030673.1", "url": "https://www.ensembl.org/id/ENSGALT00010030673.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017786.1", "url": "https://www.ensembl.org/id/ENSGALP00010017786.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 625, "start_aa": "Thr", "end_pos": 625, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr625", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:418174", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418174", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3Q1M2P8-1", "protein_name": "Epidermal growth factor receptor kinase substrate 8", "gene_name": "EPS8", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MDTSKALSSCDILQVVDFNLAQFLLQGKHGIILIFKNTSIKITMNGHISSHPSGFGMNPSQMNGYGSSATFSMDRDHSSRTSAKALYEQRKNYARDSVSSVSDISQYRVEHLTTFVLDRKDAMITVDDGIRKLKLLDAKGKVWTQDMILQVDEKAVSLIDLESKNELENFPLNTIQHCQAVMHSCSYDSILALVCKEPTQSKPDLHLFQCDEIKANLISEDVESAISDSKGGKQKRRLDVLRMISKADPGIPPPPKAPAPVPPGTVTQVDVRSRVAAWSALAADQADFEKQRNYYQQEETPEMMAARIDRDVQILNHILDDIEFFITKLQKAAEAFSELSKRKKAKKGKKKGPGEGVLTLRAKPPPPDAFVDCFQKFKHGFNLLAKLKSHIQNPSAADLVHFLFTPLNMVVQATGGPELAGSVLSPLLTKDTIDFLNYTVSADERQLWMSLGDSWMKTRAEWPKEQFIPPYVPRFRSGWEPPMLNFMGSSVEPDLYQLNESVANAAEHHRKQETKRLSTEHSSVSEYPSADGYTAFNNIYGRGPHSDQGEAAVAFKPTPLRHVDRNYDLQPKKYAKSKYDFVARNNSELSVQKDDILEILDDRKQWWKVRNASGDSGFVPNNILDIVRPPESGLGRADPPYMHTIQKQRMEYGPRATDIPSAPSPPPTPAPVPVPLPPSTPAPIPVSKLPANITRQNSSSSDSGGSIVRDSQRQKQVPVDRRKSQMEEVQDELIHRLTIGRSAAQKKFHVPRQNVPVVNITYDSTPEEVKTWLQSKGFNPVTVNSLGVLNGAQLFSLNKDELRTVCPEGARVFSQITVQKAALEDNSGSSELQEIMRRRQEKISAAASDSGVESFDEGSITN", "length": 862 }, "evidence": [ { "id": "A0A8V0YIZ6", "url": "https://omabrowser.org/oma/group/A0A8V0YIZ6/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1M3L7-1", "protein_name": "Epidermal growth factor receptor kinase substrate 8", "gene_name": "Eps8", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MNGHMSNHSSGYGIYPSQMNGYGSSPPYSQMDREHCSRTSAKALYEQRKNYARDSVSSVSDVSQYRVEHLTTFVLDRKDAMITVDDGIRKLKLLDAKGKVWTQDMILQVDDRAVSLIDLESKNELENFPLNTIQHCQAVAHTCSYDSILALVCKEPTQNKPDLHLFQCDEVKANLISEDIESAISDSKGGKQKRRPEALRMIAKADPGIPPPPRAPAPVPPGTVTQVDVRSRVAAWSAWAADQGDFEKPRQYHEQEETPEMMAARIDRDVQILNHILDDIEFFITKLQKAAEAFSELSKRKKSKKSKRKGPGEGVLTLRAKPPPPDEFVDCFQKFKHGFNLLAKLKSHIQNPSASDLVHFLFTPLNMVVQATGGPELASSVLSPLLTKDTVDFLNYTVKAEERQLWMSLGETWMKVRAEWPKEQFIPPYVPRFRNGWEPPMLNFMGAPTEQDMYQLAESVANAAEQQRKQDSKRQSTEHSSMSDYPPADGYTFSNSMYHRGPHVDQGEAALALKSTPNRHVDRNYDPVKTQPKKYAKSKYDFVARNSSELSVMKDDVLEILDDRKQWWKVRNASGDSGFVPNNILDIMRTPESGVGRTDPPYTHTIQKQRTEYGPRSADTPSAPSPPPTPAPVPVPLPPSAPAPVPVPKVPANVTRQNSSSSESGGSIARDSQRYKQLPVDRRKSQMEEVQDELFQRLTIGRSAAQRKFHVPRQNVPVINITYDSSPEEVKTWLQSKGFNPVTVSSLGVLNGAQLFSLNKDELRSVCPEGARVFSQITVQKAALEDSSGSSELQEIMRRRQEKISAAASDSGVESFDEGSSH", "length": 822 }, "evidence": [ { "id": "A0A8V0YIZ6", "url": "https://omabrowser.org/oma/group/A0A8V0YIZ6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3H9Z5-1", "protein_name": "Epidermal growth factor receptor kinase substrate 8", "gene_name": "Eps8", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MNGHTSNPPSGYGVYPSQMNGYGSSPPFSQMDREHSSKPSAKALYEQRKHYARDSVSSVSDVSQYRVEHLTTFVLDRKDAMITVDDGIRKLKLLDAKGKVWTQDMILQVDDRAVSLIDLESKNELENFPLSTIQHCQAVAHSCSYDSILALVCKEPTQSKPDLHLFQCDEVKANLISEDIESAINDSKGGKQKKRPEALRMIAKAEPGIPPPPRAPAPAPPGTVTQVDVRSRVAAWSAWAADQGDFEKPRQYQEQEETPEMVAARIDRDVQILNHILDDIEFFITKLQKAAEAFSELSKRKKSKKSKKKGPGEGVLTLRAKPPPPDEFVDCFQKFKHGFNLLAKLKSHIQNPSASDLVHFLFTPLNMVVQATGGPELASSVLSPLLTKDTVDFLNYSVTADERQLWMSLGDTWLKVRAEWPKEQFIPPYVPRFRNGWEPPMLNFMGVPTEQDMYQLAESVANVAEHQRKQDSKRLPSEHSSVSSYSPSDGYAFSNSMYNRGPHLDQAEAMAFKSMPNRHADRSHDSVKTQTKKYAKSKYDFMARNSSELSVLKDEVLEILDDRKQWWKVRNASGDSGFVPNNIMDIVRPPESGVGRADPPYTHTIQKQRMEYGPSSADTPSAPSPPPTPAPVPVPLPPSAPAPVPVPKVPANVTRQNSSSSDSGGSIVRDSQKYKQLPVDRRKSQMEEVQDELFQRLTIGRSAAQRKFHVPRQSVPVINITYDSTAEEVKTWLQTKGFNPVTVNSLGVLNGAQLFSLNKDELRSVCPEGARVFSQITVQKAALEDSNGSSELQEIMRRRQEKISAAASDSGVESFDEGSGH", "length": 821 }, "evidence": [ { "id": "A0A8V0YIZ6", "url": "https://omabrowser.org/oma/group/A0A8V0YIZ6/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q08509-1", "protein_name": "Epidermal growth factor receptor kinase substrate 8", "gene_name": "Eps8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": 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"pmid": "" }, { "name": "growth cone", "id": "GO:0030426", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030426", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIZ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIZ6" } ], "pmid": "" }, { "name": "ruffle membrane", "id": "GO:0032587", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032587", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIZ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIZ6" } ], "pmid": "" }, { "name": "stereocilium", "id": "GO:0032420", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032420", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIZ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIZ6" } ], "pmid": "" }, { "name": "NMDA selective glutamate receptor complex", "id": "GO:0017146", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017146", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIZ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIZ6" } ], "pmid": "" }, { "name": 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}, { "name": "small GTPase binding", "id": "GO:0031267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031267", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIZ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIZ6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 12, "go_terms": [ { "name": "actin polymerization-dependent cell motility", "id": "GO:0070358", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070358", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIZ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIZ6" } ], "pmid": "" }, { "name": "barbed-end actin filament capping", "id": "GO:0051016", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051016", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIZ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIZ6" } ], "pmid": "" }, { "name": "actin filament bundle assembly", "id": "GO:0051017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051017", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIZ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIZ6" } ], "pmid": "" }, { "name": "Rho protein signal transduction", "id": "GO:0007266", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007266", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIZ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIZ6" } ], "pmid": "" }, { "name": "Rac protein signal transduction", "id": "GO:0016601", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016601", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIZ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIZ6" } ], "pmid": "" }, { "name": "regulation of Rho protein signal transduction", "id": "GO:0035023", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035023", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIZ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIZ6" } ], "pmid": "" }, { "name": "regulation of cell shape", "id": "GO:0008360", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008360", "evidence": [ 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"name": "UPF3A", "type": "synonym", "evidence": [ { "id": "XP_025002461", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025002461" } ] } ], "protein_names": [ { "name": "UPF3A regulator of nonsense mediated mRNA decay", "type": "synonym", "evidence": [ { "id": "A0A8V0YLV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLV4/entry#names_and_taxonomy" } ] }, { "name": "regulator of nonsense transcripts 3A isoform X3", "type": "synonym", "evidence": [ { "id": "XP_025002461", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025002461" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_025002461.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_025002461", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025002461" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLV4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLV4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "UPF3A", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLV4", "locus": { "chromosome": "1", "start_pos": 136926886, "end_pos": 136949798, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013940", "url": "https://www.ensembl.org/id/ENSGALG00010013940" } ] } } ], "crossref": [ { "id": "A0A8V0YLV4", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YLV4", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd12727", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12727", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "418734", "url": "https://www.ncbi.nlm.nih.gov/gene/418734", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR005120", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005120", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012677", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012677", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039722", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039722", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YFU7", "url": "https://www.orthodb.org/?gene=A0A8V0YFU7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YLU9", "url": "https://www.orthodb.org/?gene=A0A8V0YLU9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YLV4", "url": "https://www.orthodb.org/?gene=A0A8V0YLV4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YM81", "url": "https://www.orthodb.org/?gene=A0A8V0YM81", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13112", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13112", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13112:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13112:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03467", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03467", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-975957", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-975957", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_025002461", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025002461", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YFU7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFU7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YFU7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFU7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLU9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLU9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLU9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLU9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLV4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLV4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLV4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLV4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YM81", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM81", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YM81-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM81-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRSEREPGLGLVRGGGGGREKRSMEVPLRRESPRREPDTTTNPPSSPAPPLPPAPVKQRDEKKTALSKVVIRRLPPCLTKEQLEEQLHPLPAHDYFEFCTADPSLYPHLYSRAYINFRNPEDILLFRDRFDGYVFIDNKGLEYPAVVEFAPFQKISKKKLKKKDAKAGSIEDDPEYRKFLESYCADEEKICANPETLLGEIEAKTRELIARRTTPLLEYIKNRKLEKQRIREEKREERRRRELEKKRLREEEKRKRREEERRKRKEAEKHKKISEKEIRIKLLKKPEKGDEPASEKHKEKDEEADTEENKWDKSPGPGSIRSKSLEGSLKELKEKSQNDSDKEQRDLERRFREKEPERQRYRLDDGRKHRTHYEFDKFVRRNEEELKWGKGYNQDRGKKGNHNYSFTVEAVDKLGSPSHAAVPARGSHPNTYGIHE", "length": 436, "header": "tr|A0A8V0YLV4-1|A0A8V0YLV4_CHICK Isoform 1 of UPF3A regulator of nonsense mediated mRNA decay OS=Gallus gallus OX=9031 GN=UPF3A PE=3 SV=1 CANONICAL=A0A8V0YLV4-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YFU7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLV4/entry#A0A8V0YFU7-1", "sequence": { "sequence": "ELNTISQIFCVLARRTTPLLEYIKNRKLEKQRIREEKREERRRRELEKKRLREEEKRKRREEERRKRKEAEKHKKISEKEIRIKLLKKPEKGDEPASEKHKEKDEEADTEENKWDKSPGPGSIRSKSLEGSLKELKEKIAQPCSCTSQGLASEHIRDPRVKPTTAVGSLLKMLLTRSMRWITQWEVALRRVRKQNKTNRRKDLWKGMNFRFNITT", "length": 215, "header": "tr|A0A8V0YFU7-1|A0A8V0YLV4_CHICK Computationally mapped isoform of UPF3A regulator of nonsense mediated mRNA decay OS=Gallus gallus OX=9031 GN=UPF3A PE=3 SV=1 CANONICAL=A0A8V0YLV4-1" }, "locus": { "chromosome": "1", "start_pos": 136934913, "end_pos": 136928063, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033426.1", "url": "https://www.ensembl.org/id/ENSGALT00010033426.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019720.1", "url": "https://www.ensembl.org/id/ENSGALP00010019720.1" } ] } }, { "isoform_ac": "A0A8V0YLU9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLV4/entry#A0A8V0YLU9-1", "sequence": { "sequence": "MKRKSVPILRLFWERLRPKQGNSLRIREEKREERRRRELEKKRLREEEKRKRREEERRKRKEAEKHKKISEKEIRIKLLKKPEKGDEPASEKHKEKDEEADTEENKWDKSPGPGSIRSKSLEGSLKELKEKSQNDSDKEQRDLERRFREKEPERQRYRLDDGRKHRTHYEFDKFVRRNEEELKWGKGYNQDRGKKGNHNYSFTVEAVDKLGKEDKCDDMASKKERIRNKDRPAMQLYQPGARIRTHTGSTSKAYDCSGKSSEDALDKKYEVDNSVGGGSEKSEEAE", "length": 286, "header": "tr|A0A8V0YLU9-1|A0A8V0YLU9_CHICK Computationally mapped isoform of UPF3A regulator of nonsense mediated mRNA decay OS=Gallus gallus OX=9031 GN=UPF3A PE=4 SV=1 CANONICAL=A0A8V0YLV4-1" }, "locus": { "chromosome": "1", "start_pos": 136938973, "end_pos": 136928124, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033432.1", "url": "https://www.ensembl.org/id/ENSGALT00010033432.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019724.1", "url": "https://www.ensembl.org/id/ENSGALP00010019724.1" } ] } }, { "isoform_ac": "A0A8V0YLV4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLV4/entry#A0A8V0YLV4-1", "sequence": { "sequence": "MRSEREPGLGLVRGGGGGREKRSMEVPLRRESPRREPDTTTNPPSSPAPPLPPAPVKQRDEKKTALSKVVIRRLPPCLTKEQLEEQLHPLPAHDYFEFCTADPSLYPHLYSRAYINFRNPEDILLFRDRFDGYVFIDNKGLEYPAVVEFAPFQKISKKKLKKKDAKAGSIEDDPEYRKFLESYCADEEKICANPETLLGEIEAKTRELIARRTTPLLEYIKNRKLEKQRIREEKREERRRRELEKKRLREEEKRKRREEERRKRKEAEKHKKISEKEIRIKLLKKPEKGDEPASEKHKEKDEEADTEENKWDKSPGPGSIRSKSLEGSLKELKEKSQNDSDKEQRDLERRFREKEPERQRYRLDDGRKHRTHYEFDKFVRRNEEELKWGKGYNQDRGKKGNHNYSFTVEAVDKLGSPSHAAVPARGSHPNTYGIHE", "length": 436, "header": "tr|A0A8V0YLV4-1|A0A8V0YLV4_CHICK Isoform 1 of UPF3A regulator of nonsense mediated mRNA decay OS=Gallus gallus OX=9031 GN=UPF3A PE=3 SV=1 CANONICAL=A0A8V0YLV4-1" }, "locus": { "chromosome": "1", "start_pos": 136949783, "end_pos": 136928230, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033443.1", "url": "https://www.ensembl.org/id/ENSGALT00010033443.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019729.1", "url": "https://www.ensembl.org/id/ENSGALP00010019729.1" } ] } }, { "isoform_ac": "A0A8V0YM81-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLV4/entry#A0A8V0YM81-1", "sequence": { "sequence": "MRSEREPGLGLVRGGGGGREKRSMEVPLRRESPRREPDTTTNPPSSPAPPLPPAPVKQRDEKKTALSKVVIRRLPPCLTKEQLEEQLHPLPAHDYFEFCTADPSKVISPWKTETFVVLPTCFCKICIHISSFTVLVIKVTRNVIMSCYYMQTVKLLTISYN", "length": 161, "header": "tr|A0A8V0YM81-1|A0A8V0YM81_CHICK Computationally mapped isoform of UPF3A regulator of nonsense mediated mRNA decay OS=Gallus gallus OX=9031 GN=UPF3A PE=3 SV=1 CANONICAL=A0A8V0YLV4-1" }, "locus": { "chromosome": "1", "start_pos": 136949783, "end_pos": 136946974, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033421.1", "url": "https://www.ensembl.org/id/ENSGALT00010033421.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019717.1", "url": "https://www.ensembl.org/id/ENSGALP00010019717.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-975957", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-975957", "resource": "Reactome", "description": "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "nuclear-transcribed mRNA catabolic process, nonsense-mediated decay", "id": "GO:0000184", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000184", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLV4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLV4" } ], "pmid": "" }, { "name": "positive regulation of translation", "id": "GO:0045727", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045727", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLV4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLV4" } ], "pmid": "" }, { "name": "negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay", "id": "GO:2000623", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000623", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLV4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLV4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLV4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLV4" } ], "pmid": "" }, { "name": "telomeric DNA binding", "id": "GO:0042162", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042162", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLV4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLV4" } ], "pmid": "" }, { "name": "protein sequestering activity", "id": "GO:0140311", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140311", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLV4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLV4" } ], "pmid": "" }, { "name": "nucleic acid binding", "id": "GO:0003676", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003676", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLV4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLV4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLV4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLV4" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLV4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLV4" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLV4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLV4" } ], "pmid": "" }, { "name": "neuron projection", "id": "GO:0043005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043005", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLV4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLV4" } ], "pmid": "" }, { "name": "exon-exon junction complex", "id": "GO:0035145", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035145", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLV4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLV4" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLV4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLV4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 338, "end_pos": 340, "annotation": "n_glycosylation_sequon" }, { "start_pos": 403, "end_pos": 405, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YLV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLV4" }, { "id": "PF03467", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03467" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "UPF3", "eco_id": "ECO_0000259", "start_pos": 67, "end_pos": 224, "start_aa": "Ser", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 338, "end_pos": 340 }, { "start_pos": 403, "end_pos": 405 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YMI9-1", "uniprot_ac": "A0A8V0YMI9", "uniprot_id": "A0A8V0YMI9_CHICK", "mass": { "chemical_mass": 120676.0, "monoisotopic_mass": 120676.0 }, "refseq": { "ac": "XP_015135994", "name": "PH and SEC7 domain-containing protein 3 isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015135994" }, "gene_names": [ { "name": "PSD3", "type": "recommended", "evidence": [ { "id": "A0A8V0YMI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMI9" } ] }, { "name": "PSD3", "type": "synonym", "evidence": [ { "id": "XP_015135994", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015135994" } ] } ], "protein_names": [ { "name": "PH and SEC7 domain-containing protein 3 isoform X3", "type": "synonym", "evidence": [ { "id": "XP_015135994", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015135994" } ] }, { "name": "Pleckstrin and Sec7 domain containing 3", "type": "synonym", "evidence": [ { "id": "A0A8V0YMI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMI9/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052572.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015135994.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015135994", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015135994" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMI9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMI9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PSD3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMI9", "locus": { "chromosome": "Z", "start_pos": 55263111, "end_pos": 55383458, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010014032", "url": "https://www.ensembl.org/id/ENSGALG00010014032" } ] } } ], "crossref": [ { "id": "A0A8V0YMI9", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YMI9", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00171", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00171", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd13295", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13295", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "770334", "url": "https://www.ncbi.nlm.nih.gov/gene/770334", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000904", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000904", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001605", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001605", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001849", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001849", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023394", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023394", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035999", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035999", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041681", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041681", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:770334", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:770334", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YG40", "url": "https://www.orthodb.org/?gene=A0A8V0YG40", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YG50", "url": "https://www.orthodb.org/?gene=A0A8V0YG50", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YG55", "url": "https://www.orthodb.org/?gene=A0A8V0YG55", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YM45", "url": "https://www.orthodb.org/?gene=A0A8V0YM45", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YM63", "url": "https://www.orthodb.org/?gene=A0A8V0YM63", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YMG9", "url": "https://www.orthodb.org/?gene=A0A8V0YMG9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YMH4", "url": "https://www.orthodb.org/?gene=A0A8V0YMH4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YMI4", "url": "https://www.orthodb.org/?gene=A0A8V0YMI4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YMI9", "url": "https://www.orthodb.org/?gene=A0A8V0YMI9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10663", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10663", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10663:SF337", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10663:SF337", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01369", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01369", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF15410", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15410", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015135994", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015135994", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YG40", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG40", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YG40-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG40-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YG50", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG50", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YG50-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG50-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YG55", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG55", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YG55-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG55-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YM45", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM45", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YM45-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM45-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YM63", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM63", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YM63-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM63-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YMG9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMG9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YMG9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMG9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YMH4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMH4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YMH4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMH4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YMI4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMI4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YMI4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMI4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YMI9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMI9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YMI9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMI9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRSLQSPGSFRHIPGVRTQGMCRREPCGGDEGAEPPAPVLSLRSALYRDMMKPGKQAEALVWDNDISAHAQSVAKAKYEFLFGLEEEKPSEVGSGHGSNTLLPHTIINEFPEYGTMEASRDALRTSSKSQAEPVTCSPEGRDRHHIPGRPPPQSVASADEPRAQVKAAQLHTAEEGLQPVGNLPEIMKISRQLEATKVQERANTYLDSETHMEKKSVPGCQNVQTAREPVAAGQEKPSDMPLPSERTAEEKMHLIIERDLAAIWTGEKQSESLQATSNKAEEVHTAKEASSHRPSVTNLEAASRVEGWAQSEEFSAYSQGKMQMGPERRLSKEAAMSKHVEFQGVEILWLQKAEDQSRKKHSLLETTSVERKTFPKTSSHSVPLMVAPSLVTLPDIAKSEVWEEPRVGAAHGAAPLALLDESGEDEVFVKDKKNCSKEETTVLARGHGRIMEEGEAAMGGYEDVLGQRQSDVSTDLYSSQFENILDNASLYYSAESLETLYSEPDSYFSFEMPLTPMIQQRMKEGSQFLERTSGQMDVFQLPPDGEVKSCCEGITNGLRNVSETLFRGDVTEVPHLGSNAGLQNMVLDSSAAMGSNKLQEKDAAGALGHDLSNGNSSNLEAARHLAERLYHLDRFKRSDVAKHLGKNNEFSKLVAEEYLKFFDFTGMTLDFSLRSFFKAFSLIGETQERERVLIHFSSRYYQCNPNTISSKDGVHCLTCALMLLNTDLHGHNIGKKMTCQEFIANLQGMNDGKDFQKGLLKALYNSIKNEKLEWAVDEEEKKKPHSDGTDEKDNGNQTKAVSRIGNSNNPFLDIPHDPNAAVYKTGFLARKIHADMDGKKTPWGKRGWKTFYAVLKGTVLYLQKDEYKPEKALSEEDLKNAVSVHHALASKATDYEKKPNVLKLKTADWRVLLFQAQSQEEMQTWINKINCVAAVFSAPPFPAAIGSQKKFSRPLLPATTTKLSQDEQLKSHEAKLKQISTELAEHRSYPPDKKLKGKEVDDYRLRDHYLEFEKNRYEIYIGLLKEGVKELLSGGENDASGLKKSHSSTSLNQESPVSAKVKRNVSERKDYRPETPSIKQKVT", "length": 1083, "header": "tr|A0A8V0YMI9-1|A0A8V0YMI9_CHICK Isoform 1 of Pleckstrin and Sec7 domain containing 3 OS=Gallus gallus OX=9031 GN=PSD3 PE=4 SV=1 CANONICAL=A0A8V0YMI9-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YG40-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMI9/entry#A0A8V0YG40-1", "sequence": { "sequence": "MCWHISIKVKAMWVRKPPFSQAQAPASLSRCRVQAAAISIVHLWLSIKPQGTVGSFPLAVRQASSNAGLQNMVLDSSAAMGSNKLQEKDAAGALGHDLSNGNSSNLEAARHLAERLYHLDRFKRSDVAKHLGKNNEFSKLVAEEYLKFFDFTGMTLDFSLRSFFKAFSLIGETQERERVLIHFSSRYYQCNPNTISSKDGVHCLTCALMLLNTDLHGHNIGKKMTCQEFIANLQGMNDGKDFQKGLLKALYNSIKNEKLEWAVDEEEKKKPHSDGTDEKDNGNQTKAVSRIGNSNNPFLDIPHDPNAAVYKTGFLARKIHADMDGKKTPWGKRGWKTFYAVLKGTVLYLQKDEYKPEKALSEEDLKNAVSVHHALASKATDYEKKPNVLKLKTADWRVLLFQAQSQEEMQTWINKINCVAAVFSAPPFPAAIGSQKKFSRPLLPATTTKLSQDEQLKSHEAKLKQISTELAEHRSYPPDKKLKGKEVDDYRLRDHYLEFEKNRYEIYIGLLKEGVKELLSGGENDASGLKKSHSSTSLNQESPVSAKVKRNVSERKDYRPETPSIKQKVT", "length": 570, "header": "tr|A0A8V0YG40-1|A0A8V0YMI9_CHICK Computationally mapped isoform of Pleckstrin and Sec7 domain containing 3 OS=Gallus gallus OX=9031 GN=PSD3 PE=4 SV=1 CANONICAL=A0A8V0YMI9-1" }, "locus": { "chromosome": "Z", "start_pos": 55349298, "end_pos": 55277400, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033663.1", "url": "https://www.ensembl.org/id/ENSGALT00010033663.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019822.1", "url": "https://www.ensembl.org/id/ENSGALP00010019822.1" } ] } }, { "isoform_ac": "A0A8V0YG50-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMI9/entry#A0A8V0YG50-1", "sequence": { "sequence": "MEASRDALRTSSKSQAEPVTCSPEGRDRHHIPGRPPPQSVASADEPRAQVKAAQLHTAEEGLQPVGNLPEIMKISRQLEATKVQERANTYLDSETHMEKKSVPGCQNVQTAREPVAAGQEKPSDMPLPSERTAEEKMHLIIERDLAAIWTGEKQSESLQATSNKAEEVHTAKEASSHRPSVTNLEAASRVEGWAQSEEFSAYSQGKMQMGPERRLSKEAAMSKHVEFQGVEILWLQKAEDQSRKKHSLLETTSVERKTFPKTSSHSVPLMVAPSLVTLPDIAKSEVWEEPRVGAAHGAAPLALLDESGEDEVFVKDKKNCSKEETTVLARGHGRIMEEGEAAMGGYEDVLGQRQSDVSTDLYSSQFENILDNASLYYSAESLETLYSEPDSYFSFEMPLTPMIQQRMKEGSQFLERTSGQMDVFQLPPDGEVKSCCEGITNGLRNVSETLFRGDVTEVPHLGSNAGLQNMVLDSSAAMGSNKLQEKDAAGALGHDLSNGNSSNLEAARHLAERLYHLDRFKRSDVAKHLGKNNEFSKLVAEEYLKFFDFTGMTLDFSLRSFFKAFSLIGETQERERVLIHFSSRYYQCNPNTISSKDGVHCLTCALMLLNTDLHGHNIGKKMTCQEFIANLQGMNDGKDFQKGLLKALYNSIKNEKLEWAVDEEEKKKPHSDGTDEKDNGNQTKAVSRIGNSNNPFLDIPHDPNAAVYKTGFLARKIHADMDGKKTPWGKRGWKTFYAVLKGTVLYLQKDEYKPEKALSEEDLKNAVSVHHALASKATDYEKKPNVLKLKTADWRVLLFQAQSQEEMQTWINKINCVAAVFSAPPFPAAIGSQKKFSRPLLPATTTKLSQDEQLKSHEAKLKQISTELAEHRSYPPDKKLKGKEVDDYRLRDHYLEFEKNRYEIYIGLLKEGVKELLSGGENDASGLKKSHSSTSLNQESPVSAKVKRNVSERKDYRPETPSIKQKVT", "length": 968, "header": "tr|A0A8V0YG50-1|A0A8V0YMI9_CHICK Computationally mapped isoform of Pleckstrin and Sec7 domain containing 3 OS=Gallus gallus OX=9031 GN=PSD3 PE=4 SV=1 CANONICAL=A0A8V0YMI9-1" }, "locus": { "chromosome": "Z", "start_pos": 55358807, "end_pos": 55277400, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033677.1", "url": "https://www.ensembl.org/id/ENSGALT00010033677.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019832.1", "url": "https://www.ensembl.org/id/ENSGALP00010019832.1" } ] } }, { "isoform_ac": "A0A8V0YG55-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMI9/entry#A0A8V0YG55-1", "sequence": { "sequence": "MDGAGRAAEALVWDNDISAHAQSVAKAKYEFLFGLEEEKPSEVGSGHGSNTLLPHTIINEFPEYGTMEASRDALRTSSKSQAEPVTCSPEGRDRHHIPGRPPPQSVASADEPRAQVKAAQLHTAEEGLQPVGNLPEIMKISRQLEATKVQERANTYLDSETHMEKKSVPGCQNVQTAREPVAAGQEKPSDMPLPSERTAEEKMHLIIERDLAAIWTGEKQSESLQATSNKAEEVHTAKEASSHRPSVTNLEAASRVEGWAQSEEFSAYSQGKMQMGPERRLSKEAAMSKHVEFQGVEILWLQKAEDQSRKKHSLLETTSVERKTFPKTSSHSVPLMVAPSLVTLPDIAKSEVWEEPRVGAAHGAAPLALLDESGEDEVFVKDKKNCSKEETTVLARGHGRIMEEGEAAMGGYEDVLGQRQSDVSTDLYSSQFENILDNASLYYSAESLETLYSEPDSYFSFEMPLTPMIQQRMKEGSQFLERTSGQMDVFQLPPDGEVKSCCEGITNGLRNVSETLFRGDVTEVPHLGSNAGLQNMVLDSSAAMGSNKLQEKDAAGALGHDLSNGNSSNLEAARHLAERLYHLDRFKRSDVAKHLGKNNEFSKLVAEEYLKFFDFTGMTLDFSLRSFFKAFSLIGETQERERVLIHFSSRYYQCNPNTISSKDGVHCLTCALMLLNTDLHGHNIGKKMTCQEFIANLQGMNDGKDFQKGLLKALYNSIKNEKLEWAVDEEEKKKPHSDGTDEKDNGNQTKAVSRIGNSNNPFLDIPHDPNAAVYKTGFLARKIHADMDGKKTPWGKRGWKTFYAVLKGTVLYLQKDEYKPEKALSEEDLKNAVSVHHALASKATDYEKKPNVLKLKTADWRVLLFQAQSQEEMQTWINKINCVAAVFSAPPFPAAIGSQKKFSRPLLPATTTKLSQDEQLKSHEAKLKQISTELAEHRSYPPDKKLKGKEVDDYRLRDHYLEFEKNRYEIYIGLLKEGVKELLSGGENDASGLKKSHSSTSLNQESPVSAKASQAPN", "length": 1017, "header": "tr|A0A8V0YG55-1|A0A8V0YMI9_CHICK Computationally mapped isoform of Pleckstrin and Sec7 domain containing 3 OS=Gallus gallus OX=9031 GN=PSD3 PE=4 SV=1 CANONICAL=A0A8V0YMI9-1" }, "locus": { "chromosome": "Z", "start_pos": 55383347, "end_pos": 55274239, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033690.1", "url": "https://www.ensembl.org/id/ENSGALT00010033690.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019837.1", "url": "https://www.ensembl.org/id/ENSGALP00010019837.1" } ] } }, { "isoform_ac": "A0A8V0YM45-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMI9/entry#A0A8V0YM45-1", "sequence": { "sequence": "MHNAGLQNMVLDSSAAMGSNKLQEKDAAGALGHDLSNGNSSNLEAARHLAERLYHLDRFKRSDVAKHLGKNNEFSKLVAEEYLKFFDFTGMTLDFSLRSFFKAFSLIGETQERERVLIHFSSRYYQCNPNTISSKDGVHCLTCALMLLNTDLHGHNIGKKMTCQEFIANLQGMNDGKDFQKGLLKALYNSIKNEKLEWAVDEEEKKKPHSDGTDEKDNGNQTKAVSRIGNSNNPFLDIPHDPNAAVYKTGFLARKIHADMDGKKTPWGKRGWKTFYAVLKGTVLYLQKDEYKPEKALSEEDLKNAVSVHHALASKATDYEKKPNVLKLKTADWRVLLFQAQSQEEMQTWINKINCVAAVFSAPPFPAAIGSQKKFSRPLLPATTTKLSQDEQLKSHEAKLKQISTELAEHRSYPPDKKLKGKEVDDYRLRDHYLEFEKNRYEIYIGLLKEGVKELLSGGENDASGLKKSHSSTSLNQESPVSAKASQAPN", "length": 490, "header": "tr|A0A8V0YM45-1|A0A8V0YM45_CHICK Computationally mapped isoform of Pleckstrin and Sec7 domain containing 3 OS=Gallus gallus OX=9031 GN=PSD3 PE=4 SV=1 CANONICAL=A0A8V0YMI9-1" }, "locus": { "chromosome": "Z", "start_pos": 55353092, "end_pos": 55274239, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033668.1", "url": "https://www.ensembl.org/id/ENSGALT00010033668.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019826.1", "url": "https://www.ensembl.org/id/ENSGALP00010019826.1" } ] } }, { "isoform_ac": "A0A8V0YM63-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMI9/entry#A0A8V0YM63-1", "sequence": { "sequence": "MDGAGRAAEALVWDNDISAHAQSVAKAKYEFLFGLEEEKPSEVGSGHGSNTLLPHTIINEFPEYGTMEASRDALRTSSKSQAEPVTCSPEGRDRHHIPGRPPPQSVASADEPRAQVKAAQLHTAEEGLQPVGNLPEIMKISRQLEATKVQERANTYLDSETHMEKKSVPGCQNVQTAREPVAAGQEKPSDMPLPSERTAEEKMHLIIERDLAAIWTGEKQSESLQATSNKAEEVHTAKEASSHRPSVTNLEAASRVEGWAQSEEFSAYSQGKMQMGPERRLSKEAAMSKHVEFQGVEILWLQKAEDQSRKKHSLLETTSVERKTFPKTSSHSVPLMVAPSLVTLPDIAKSEVWEEPRVGAAHGAAPLALLDESGEDEVFVKDKKNCSKEETTVLARGHGRIMEEGEAAMGGYEDVLGQRQSDVSTDLYSSQFENILDNASLYYSAESLETLYSEPDSYFSFEMPLTPMIQQRMKEGSQFLERTSGQMDVFQLPPDGEVKSCCEGITNGLRNVSETLFRGDVTEVPHLGSNAGLQNMVLDSSAAMGSNKLQEKDAAGALGHDLSNGNSSNLEAARHLAERLYHLDRFKRSDVAKHLGKNNEFSKLVAEEYLKFFDFTGMTLDFSLRSFFKAFSLIGETQERERVLIHFSSRYYQCNPNTISSKDGVHCLTCALMLLNTDLHGHNIGKKMTCQEFIANLQGMNDGKDFQKGLLKALYNSIKNEKLEWAVDEEEKKKPHSDGTDEKDNGNQTKAVSRIGNSNNPFLDIPHDPNAAVYKTGFLARKIHADMDGKKTPWGKRGWKTFYAVLKGTVLYLQKDEYKPEKALSEEDLKNAVSVHHALASKATDYEKKPNVLKLKTADWRVLLFQAQSQEEMQTWINKINCVAAVFSAPPFPAAIGSQKKFSRPLLPATTTKLSQDEQLKSHEAKLKQISTELAEHRSYPPDKKLKGKEVDDYRLRDHYLEFEKNRYEIYIGLLKEGVKELLSGGENDASGLKKSHSSTSLNQESPVSAKVNSSHGLLARMHVSRNLWWIQPPEQVCALSLGK", "length": 1044, "header": "tr|A0A8V0YM63-1|A0A8V0YM63_CHICK Computationally mapped isoform of Pleckstrin and Sec7 domain containing 3 OS=Gallus gallus OX=9031 GN=PSD3 PE=4 SV=1 CANONICAL=A0A8V0YMI9-1" }, "locus": { "chromosome": "Z", "start_pos": 55383347, "end_pos": 55264017, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033695.1", "url": "https://www.ensembl.org/id/ENSGALT00010033695.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019841.1", "url": "https://www.ensembl.org/id/ENSGALP00010019841.1" } ] } }, { "isoform_ac": "A0A8V0YMG9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMI9/entry#A0A8V0YMG9-1", "sequence": { "sequence": "MIGVNSVQSTSKVRVRATGSVKYSREESLWRQSHRSKSMKISNSSEFSTKESKALYNSIKNEKLEWAVDEEEKKKPHSDGTDEKDNGNQTKAVSRIGNSNNPFLDIPHDPNAAVYKTGFLARKIHADMDGKKTPWGKRGWKTFYAVLKGTVLYLQKDEYKPEKALSEEDLKNAVSVHHALASKATDYEKKPNVLKLKTADWRVLLFQAQSQEEMQTWINKINCVAAVFSAPPFPAAIGSQKKFSRPLLPATTTKLSQDEQLKSHEAKLKQISTELAEHRSYPPDKKLKGKEVDDYRLRDHYLEFEKNRYEIYIGLLKEGVKELLSGGENDASGLKKSHSSTSLNQESPVSAKASQAPN", "length": 358, "header": "tr|A0A8V0YMG9-1|A0A8V0YMG9_CHICK Computationally mapped isoform of Pleckstrin and Sec7 domain containing 3 OS=Gallus gallus OX=9031 GN=PSD3 PE=4 SV=1 CANONICAL=A0A8V0YMI9-1" }, "locus": { "chromosome": "Z", "start_pos": 55319570, "end_pos": 55274239, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033652.1", "url": "https://www.ensembl.org/id/ENSGALT00010033652.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019814.1", "url": "https://www.ensembl.org/id/ENSGALP00010019814.1" } ] } }, { "isoform_ac": "A0A8V0YMH4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMI9/entry#A0A8V0YMH4-1", "sequence": { "sequence": "MVLDSSAAMGSNKLQEKDAAGALGHDLSNGNSSNLEAARHLAERLYHLDRFKRSDVAKHLGKNNEFSKLVAEEYLKFFDFTGMTLDFSLRSFFKAFSLIGETQERERVLIHFSSRYYQCNPNTISSKDGVHCLTCALMLLNTDLHGHALYNSIKNEKLEWAVDEEEKKKPHSDGTDEKDNGNQTKAVSRIGNSNNPFLDIPHDPNAAVYKTGFLARKIHADMDGKKTPWGKRGWKTFYAVLKGTVLYLQKDEYKPEKALSEEDLKNAVSVHHALASKATDYEKKPNVLKLKTADWRVLLFQAQSQEEMQTWINKINCVAAVFSAPPFPAAIGSQKKFSRPLLPATTTKLSQDEQLKSHEAKLKQISTELAEHRSYPPDKKLKGKEVDDYRLRDHYLEFEKNRYEIYIGLLKEGVKELLSGGENDASGLKKSHSSTSLNQESPVSAKVKRNVSERKDYRPETPSIKQKVT", "length": 469, "header": "tr|A0A8V0YMH4-1|A0A8V0YMH4_CHICK Computationally mapped isoform of Pleckstrin and Sec7 domain containing 3 OS=Gallus gallus OX=9031 GN=PSD3 PE=4 SV=1 CANONICAL=A0A8V0YMI9-1" }, "locus": { "chromosome": "Z", "start_pos": 55343470, "end_pos": 55277400, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033657.1", "url": "https://www.ensembl.org/id/ENSGALT00010033657.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019819.1", "url": "https://www.ensembl.org/id/ENSGALP00010019819.1" } ] } }, { "isoform_ac": "A0A8V0YMI4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMI9/entry#A0A8V0YMI4-1", "sequence": { "sequence": "MGNCWSYSNLCSGHGSNTLLPHTIINEFPEYGTMEASRDALRTSSKSQAEPVTCSPEGRDRHHIPGRPPPQSVASADEPRAQVKAAQLHTAEEGLQPVGNLPEIMKISRQLEATKVQERANTYLDSETHMEKKSVPGCQNVQTAREPVAAGQEKPSDMPLPSERTAEEKMHLIIERDLAAIWTGEKQSESLQATSNKAEEVHTAKEASSHRPSVTNLEAASRVEGWAQSEEFSAYSQGKMQMGPERRLSKEAAMSKHVEFQGVEILWLQKAEDQSRKKHSLLETTSVERKTFPKTSSHSVPLMVAPSLVTLPDIAKSEVWEEPRVGAAHGAAPLALLDESGEDEVFVKDKKNCSKEETTVLARGHGRIMEEGEAAMGGYEDVLGQRQSDVSTDLYSSQFENILDNASLYYSAESLETLYSEPDSYFSFEMPLTPMIQQRMKEGSQFLERTSGQMDVFQLPPDGEVKSCCEGITNGLRNVSETLFRGDVTEVPHLGSNAGLQNMVLDSSAAMGSNKLQEKDAAGALGHDLSNGNSSNLEAARHLAERLYHLDRFKRSDVAKHLGKNNEFSKLVAEEYLKFFDFTGMTLDFSLRSFFKAFSLIGETQERERVLIHFSSRYYQCNPNTISSKDGVHCLTCALMLLNTDLHGHNIGKKMTCQEFIANLQGMNDGKDFQKGLLKALYNSIKNEKLEWAVDEEEKKKPHSDGTDEKDNGNQTKAVSRIGNSNNPFLDIPHDPNAAVYKTGFLARKIHADMDGKKTPWGKRGWKTFYAVLKGTVLYLQKDEYKPEKALSEEDLKNAVSVHHALASKATDYEKKPNVLKLKTADWRVLLFQAQSQEEMQTWINKINCVAAVFSAPPFPAAIGSQKKFSRPLLPATTTKLSQDEQLKSHEAKLKQISTELAEHRSYPPDKKLKGKEVDDYRLRDHYLEFEKNRYEIYIGLLKEGVKELLSGGENDASGLKKSHSSTSLNQESPVSAKVKRNVSERKDYRPETPSIKQKVT", "length": 1001, "header": "tr|A0A8V0YMI4-1|A0A8V0YMI4_CHICK Computationally mapped isoform of Pleckstrin and Sec7 domain containing 3 OS=Gallus gallus OX=9031 GN=PSD3 PE=4 SV=1 CANONICAL=A0A8V0YMI9-1" }, "locus": { "chromosome": "Z", "start_pos": 55362288, "end_pos": 55277400, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033672.1", "url": "https://www.ensembl.org/id/ENSGALT00010033672.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019829.1", "url": "https://www.ensembl.org/id/ENSGALP00010019829.1" } ] } }, { "isoform_ac": "A0A8V0YMI9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMI9/entry#A0A8V0YMI9-1", "sequence": { "sequence": "MRSLQSPGSFRHIPGVRTQGMCRREPCGGDEGAEPPAPVLSLRSALYRDMMKPGKQAEALVWDNDISAHAQSVAKAKYEFLFGLEEEKPSEVGSGHGSNTLLPHTIINEFPEYGTMEASRDALRTSSKSQAEPVTCSPEGRDRHHIPGRPPPQSVASADEPRAQVKAAQLHTAEEGLQPVGNLPEIMKISRQLEATKVQERANTYLDSETHMEKKSVPGCQNVQTAREPVAAGQEKPSDMPLPSERTAEEKMHLIIERDLAAIWTGEKQSESLQATSNKAEEVHTAKEASSHRPSVTNLEAASRVEGWAQSEEFSAYSQGKMQMGPERRLSKEAAMSKHVEFQGVEILWLQKAEDQSRKKHSLLETTSVERKTFPKTSSHSVPLMVAPSLVTLPDIAKSEVWEEPRVGAAHGAAPLALLDESGEDEVFVKDKKNCSKEETTVLARGHGRIMEEGEAAMGGYEDVLGQRQSDVSTDLYSSQFENILDNASLYYSAESLETLYSEPDSYFSFEMPLTPMIQQRMKEGSQFLERTSGQMDVFQLPPDGEVKSCCEGITNGLRNVSETLFRGDVTEVPHLGSNAGLQNMVLDSSAAMGSNKLQEKDAAGALGHDLSNGNSSNLEAARHLAERLYHLDRFKRSDVAKHLGKNNEFSKLVAEEYLKFFDFTGMTLDFSLRSFFKAFSLIGETQERERVLIHFSSRYYQCNPNTISSKDGVHCLTCALMLLNTDLHGHNIGKKMTCQEFIANLQGMNDGKDFQKGLLKALYNSIKNEKLEWAVDEEEKKKPHSDGTDEKDNGNQTKAVSRIGNSNNPFLDIPHDPNAAVYKTGFLARKIHADMDGKKTPWGKRGWKTFYAVLKGTVLYLQKDEYKPEKALSEEDLKNAVSVHHALASKATDYEKKPNVLKLKTADWRVLLFQAQSQEEMQTWINKINCVAAVFSAPPFPAAIGSQKKFSRPLLPATTTKLSQDEQLKSHEAKLKQISTELAEHRSYPPDKKLKGKEVDDYRLRDHYLEFEKNRYEIYIGLLKEGVKELLSGGENDASGLKKSHSSTSLNQESPVSAKVKRNVSERKDYRPETPSIKQKVT", "length": 1083, "header": "tr|A0A8V0YMI9-1|A0A8V0YMI9_CHICK Isoform 1 of Pleckstrin and Sec7 domain containing 3 OS=Gallus gallus OX=9031 GN=PSD3 PE=4 SV=1 CANONICAL=A0A8V0YMI9-1" }, "locus": { "chromosome": "Z", "start_pos": 55377397, "end_pos": 55277400, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033683.1", "url": "https://www.ensembl.org/id/ENSGALT00010033683.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019834.1", "url": "https://www.ensembl.org/id/ENSGALP00010019834.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:770334", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:770334", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "phospholipid binding", "id": "GO:0005543", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005543", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMI9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMI9" } ], "pmid": "" }, { "name": "guanyl-nucleotide exchange factor activity", "id": "GO:0005085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005085", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMI9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMI9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "ruffle membrane", "id": "GO:0032587", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032587", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMI9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMI9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "regulation of ARF protein signal transduction", "id": "GO:0032012", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032012", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMI9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMI9" } ], "pmid": "" }, { "name": "vesicle-mediated transport", "id": "GO:0016192", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016192", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMI9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMI9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1064, "end_pos": 1066, "annotation": "n_glycosylation_sequon" }, { "start_pos": 434, "end_pos": 436, "annotation": "n_glycosylation_sequon" }, { "start_pos": 487, "end_pos": 489, "annotation": "n_glycosylation_sequon" }, { "start_pos": 560, "end_pos": 562, "annotation": "n_glycosylation_sequon" }, { "start_pos": 615, "end_pos": 617, "annotation": "n_glycosylation_sequon" }, { "start_pos": 796, "end_pos": 798, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YMI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMI9" }, { "id": "PS50003", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50003" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PH", "eco_id": "ECO_0000259", "start_pos": 821, "end_pos": 934, "start_aa": "Ala", "end_aa": "Ala", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0YMI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMI9" }, { "id": "PS50190", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50190" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SEC7", "eco_id": "ECO_0000259", "start_pos": 581, "end_pos": 770, "start_aa": "Gly", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1064, "end_pos": 1066 }, { "start_pos": 434, "end_pos": 436 }, { "start_pos": 487, "end_pos": 489 }, { "start_pos": 560, "end_pos": 562 }, { "start_pos": 615, "end_pos": 617 }, { "start_pos": 796, "end_pos": 798 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": 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"count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YMA7-1", "uniprot_ac": "A0A8V0YMA7", "uniprot_id": "A0A8V0YMA7_CHICK", "mass": { "chemical_mass": 71020.0, "monoisotopic_mass": 71020.0 }, "refseq": {}, "gene_names": [ { "name": "HNRNPR", "type": "recommended", "evidence": [ { "id": "A0A8V0YMA7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMA7" } ] } ], "protein_names": [ { "name": "Heteroous nuclear ribonucleoprotein R", "type": "synonym", "evidence": [ { "id": "A0A8V0YMA7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMA7/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMA7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMA7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "HNRNPR", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMA7", "locus": { "chromosome": "23", "start_pos": 1946242, "end_pos": 1924431, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010014082", "url": "https://www.ensembl.org/id/ENSGALG00010014082" } ] } } ], "crossref": [ { "id": "A0A8V0YMA7", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YMA7", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd12482", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12482", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd12488", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12488", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd12494", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12494", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd21067", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd21067", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "419570", "url": "https://www.ncbi.nlm.nih.gov/gene/419570", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000504", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000504", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006535", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006535", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012677", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012677", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034410", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034410", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034411", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034411", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041337", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041337", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:419570", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419570", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "NTAYEDY", "url": "https://omabrowser.org/oma/group/NTAYEDY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YGA1", "url": "https://www.orthodb.org/?gene=A0A8V0YGA1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YMA1", "url": "https://www.orthodb.org/?gene=A0A8V0YMA1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YMA7", "url": "https://www.orthodb.org/?gene=A0A8V0YMA7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YMB4", "url": "https://www.orthodb.org/?gene=A0A8V0YMB4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YUF0", "url": "https://www.orthodb.org/?gene=A0A8V0YUF0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21245", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21245", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00076", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00076", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF18360", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18360", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-72163", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-72163", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9770562", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9770562", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YGA1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGA1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YGA1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGA1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YMA1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMA1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YMA1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMA1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YMA7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMA7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YMA7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMA7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YMB4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMB4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YMB4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMB4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YUF0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUF0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YUF0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUF0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MANQVNGNAVQLKEEEEPMDTSSVTHTEHYKTLIEAGLPQKVAERLDEIFQTGLVAYVDLDERAIDALREFNEEGALSVLQQFKESDLSHVQNKSAFLCGVMKTYRQREKQGSKVQESTKGPDEAKIKALLERTGYTLDVTTGQRKYGGPPPDTVYSGVQPGIGTEVFVGKIPRDLYEDELVPLFEKAGPIWDLRLMMDPLSGQNRGYAFITFCSKDAAQEAVKLCDNYEIRPGKHLGVCISVANNRLFVGSIPKNKTKENILEEFNKVTEGLVDVILYHQPDDKKKNRGFCFLEYEDHKSAAQARRRLMSGKVKVWGNVVTVEWADPVEEPDPEVMAKVKVLFVRNLATTVTEEILEKSFSEFGKLERVKKLKDYAFVHFEDRGAAVKAMNEMNGKEIEGEEIEIVLAKPPDKKRKERQAARQASRSTAYEDYYYYPPPRMPPPIRGRGRGGRGGYGYPPDYYGYEDYYDDYYGYDYHDYRGGYEDPYYGYDDGYAIRGRGGGGRGGRGAPPPPRGRGAPPPRGRAGYSQRGAPMGPPRGARGGRGGPAQQQRGRGARGARGNRGGNVGGKRKADGYNQPDSKRRQTNNQQNWGSQPIAQQPLQQGGDYAGNYGYNNDNQEFYQDTYGQQWK", "length": 633, "header": "tr|A0A8V0YMA7-1|A0A8V0YMA7_CHICK Isoform 1 of Heteroous nuclear ribonucleoprotein R OS=Gallus gallus OX=9031 GN=HNRNPR PE=1 SV=1 CANONICAL=A0A8V0YMA7-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YGA1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMA7/entry#A0A8V0YGA1-1", "sequence": { "sequence": "MRRRRSARHLPSLLGPELRRAGPAPLLNFFQQHNKMANQVNGNAVQLKEEEEPMDTSSVTHTEHYKTLIEAGLPQKVAERLDEIFQTGLVAYVDLDERAIDALREFNEEGALSVLQQFKESDLSHVQNKSAFLCGVMKTYRQREKQGSKVQESTKGPDEAKIKALLERTGYTLDVTTGQRKYGGPPPDTVYSGVQPGIGTEVFVGKIPRDLYEDELVPLFEKAGPIWDLRLMMDPLSGQNRGYAFITFCSKDAAQEAVKLCDNYEIRPGKHLGVCISVANNRLFVGSIPKNKTKENILEEFNKVTEGLVDVILYHQPDDKKKNRGFCFLEYEDHKSAAQARRRLMSGKVKVWGNVVTVEWADPVEEPDPEVMAKVKVLFVRNLATTVTEEILEKSFSEFGKLERVKKLKDYAFVHFEDRGAAVKAMNEMNGKEIEGEEIEIVLAKPPDKKRKERQAARQASRSTAYEDYYYYPPPRMPPPIRGRGRGGRGGYGYPPDYYGYEDYYDDYYGYDYHDYRGGYEDPYYGYDDGYAIRGRGGGGRGGRGAPPPPRGRGAPPPRGRAGYSQRGAPMGPPRGARGGRGGPAQQQRGRGARGARGNRGGNVGGKRKADGYNQPDSKRRQTNNQQNWGSQPIAQQPLQQGGDYAGNYGYNNDNQEFYQDTYGQQWK", "length": 668, "header": "tr|A0A8V0YGA1-1|A0A8V0YMA7_CHICK Computationally mapped isoform of Heteroous nuclear ribonucleoprotein R OS=Gallus gallus OX=9031 GN=HNRNPR PE=1 SV=1 CANONICAL=A0A8V0YMA7-1" }, "locus": { "chromosome": "23", "start_pos": 1945565, "end_pos": 1924477, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033812.1", "url": "https://www.ensembl.org/id/ENSGALT00010033812.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019889.1", "url": "https://www.ensembl.org/id/ENSGALP00010019889.1" } ] } }, { "isoform_ac": "A0A8V0YMA1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMA7/entry#A0A8V0YMA1-1", "sequence": { "sequence": "MAVAAPSRPLSAAAGRRRCRRGVVGGLPRAWTENPSLSQRSVQRCAARCGTAAGRRSPERCCWDIASLNGLLRLVAYVDLDERAIDALREFNEEGALSVLQQFKESDLSHVQNKSAFLCGVMKTYRQREKQGSKVQESTKGPDEAKIKALLERTGYTLDVTTGQRKYGGPPPDTVYSGVQPGIGTEVFVGKIPRDLYEDELVPLFEKAGPIWDLRLMMDPLSGQNRGYAFITFCSKDAAQEAVKLCDNYEIRPGKHLGVCISVANNRLFVGSIPKNKTKENILEEFNKVTEGLVDVILYHQPDDKKKNRGFCFLEYEDHKSAAQARRRLMSGKVKVWGNVVTVEWADPVEEPDPEVMAKVKVLFVRNLATTVTEEILEKSFSEFGKLERVKKLKDYAFVHFEDRGAAVKAMNEMNGKEIEGEEIEIVLAKPPDKKRKERQAARQASRSTAYEDYYYYPPPRMPPPIRGRGRGGRGGYGYPPDYYGYEDYYDDYYGYDYHDYRGGYEDPYYGYDDGYAIRGRGGGGRGGRGAPPPPRGRGAPPPRGRAGYSQRGAPMGPPRGARGGRGGPAQQQRGRGARGARGNRGGNVGGKRKADGYNQPDSKRRQTNNQQNWGSQPIAQQPLQQGGDYAGNYGYNNDNQEFYQDTYGQQWK", "length": 653, "header": "tr|A0A8V0YMA1-1|A0A8V0YMA1_CHICK Computationally mapped isoform of Heteroous nuclear ribonucleoprotein R OS=Gallus gallus OX=9031 GN=HNRNPR PE=1 SV=1 CANONICAL=A0A8V0YMA7-1" }, "locus": { "chromosome": "23", "start_pos": 1945565, "end_pos": 1924975, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033790.1", "url": "https://www.ensembl.org/id/ENSGALT00010033790.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019878.1", "url": "https://www.ensembl.org/id/ENSGALP00010019878.1" } ] } }, { "isoform_ac": "A0A8V0YMA7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMA7/entry#A0A8V0YMA7-1", "sequence": { "sequence": "MANQVNGNAVQLKEEEEPMDTSSVTHTEHYKTLIEAGLPQKVAERLDEIFQTGLVAYVDLDERAIDALREFNEEGALSVLQQFKESDLSHVQNKSAFLCGVMKTYRQREKQGSKVQESTKGPDEAKIKALLERTGYTLDVTTGQRKYGGPPPDTVYSGVQPGIGTEVFVGKIPRDLYEDELVPLFEKAGPIWDLRLMMDPLSGQNRGYAFITFCSKDAAQEAVKLCDNYEIRPGKHLGVCISVANNRLFVGSIPKNKTKENILEEFNKVTEGLVDVILYHQPDDKKKNRGFCFLEYEDHKSAAQARRRLMSGKVKVWGNVVTVEWADPVEEPDPEVMAKVKVLFVRNLATTVTEEILEKSFSEFGKLERVKKLKDYAFVHFEDRGAAVKAMNEMNGKEIEGEEIEIVLAKPPDKKRKERQAARQASRSTAYEDYYYYPPPRMPPPIRGRGRGGRGGYGYPPDYYGYEDYYDDYYGYDYHDYRGGYEDPYYGYDDGYAIRGRGGGGRGGRGAPPPPRGRGAPPPRGRAGYSQRGAPMGPPRGARGGRGGPAQQQRGRGARGARGNRGGNVGGKRKADGYNQPDSKRRQTNNQQNWGSQPIAQQPLQQGGDYAGNYGYNNDNQEFYQDTYGQQWK", "length": 633, "header": "tr|A0A8V0YMA7-1|A0A8V0YMA7_CHICK Isoform 1 of Heteroous nuclear ribonucleoprotein R OS=Gallus gallus OX=9031 GN=HNRNPR PE=1 SV=1 CANONICAL=A0A8V0YMA7-1" }, "locus": { "chromosome": "23", "start_pos": 1945565, "end_pos": 1930616, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033799.1", "url": "https://www.ensembl.org/id/ENSGALT00010033799.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019883.1", "url": "https://www.ensembl.org/id/ENSGALP00010019883.1" } ] } }, { "isoform_ac": "A0A8V0YMB4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMA7/entry#A0A8V0YMB4-1", "sequence": { "sequence": "MRRRRSARHLPSLLGPELRRAGPAPVTYVDLDERAIDALREFNEEGALSVLQQFKESDLSHVQNKSAFLCGVMKTYRQREKQGSKVQESTKGPDEAKIKALLERTGYTLDVTTGQRKYGGPPPDTVYSGVQPGIGTEVFVGKIPRDLYEDELVPLFEKAGPIWDLRLMMDPLSGQNRGYAFITFCSKDAAQEAVKLCDNYEIRPGKHLGVCISVANNRLFVGSIPKNKTKENILEEFNKVTEGLVDVILYHQPDDKKKNRGFCFLEYEDHKSAAQARRRLMSGKVKVWGNVVTVEWADPVEEPDPEVMAKVKVLFVRNLATTVTEEILEKSFSEFGKLERVKKLKDYAFVHFEDRGAAVKAMNEMNGKEIEGEEIEIVLAKPPDKKRKERQAARQASRSTAYEDYYYYPPPRMPPPIRGRGRGGRGGYGYPPDYYGYEDYYDDYYGYDYHDYRGGYEDPYYGYDDGYAIRGRGGGGRGGRGAPPPPRGRGAPPPRGRAGYSQRGAPMGPPRGARGGRGGPAQQQRGRGARGARGNRGGNVGGKRKADGYNQPDSKRRQTNNQQNWGSQPIAQQPLQQGGDYAGNYGYNNDNQEFYQDTYGQQWK", "length": 604, "header": "tr|A0A8V0YMB4-1|A0A8V0YMB4_CHICK Computationally mapped isoform of Heteroous nuclear ribonucleoprotein R OS=Gallus gallus OX=9031 GN=HNRNPR PE=1 SV=1 CANONICAL=A0A8V0YMA7-1" }, "locus": { "chromosome": "23", "start_pos": 1945565, "end_pos": 1924477, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033806.1", "url": "https://www.ensembl.org/id/ENSGALT00010033806.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019888.1", "url": "https://www.ensembl.org/id/ENSGALP00010019888.1" } ] } }, { "isoform_ac": "A0A8V0YUF0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMA7/entry#A0A8V0YUF0-1", "sequence": { "sequence": "MATKEEEPMDTSSVTHTEHYKTLIEAGLPQKVAERLDEIFQTGLVAYVDLDERAIDALREFNEEGALSVLQQFKESDLSHVQNKSAFLCGVMKTYRQREKQGSKVQESTKGPDEAKIKALLERTGYTLDVTTGQRKYGGPPPDTVYSGVQPGIGTEVFVGKIPRDLYEDELVPLFEKAGPIWDLRLMMDPLSGQNRGYAFITFCSKDAAQEAVKLVKVLFVRNLATTVTEEILEKSFSEFGKLERVKKLKDYAFVHFEDRGAAVKAMNEMNGKEIEGEEIEIVLAKPPDKKRKERQAARQASRNYYYYPPPRMPPPIRGRGRGGRGGYGYPPDYYGYEDYYDDYYGYDYHDYRGGYEDPYYGYDDGYAIRGRGGGGRGGRGAPPPPRGRGAPPPRGRAGYSQRGAPMGPPRGARGGRGGPAQQQRGRGARGARGNRGGNVGGKRKADGYNQPDSKRRQTNNQQNWGSQPIAQQPLQQGGDYAGNYGYNNDNQEFYQDTYGQQWK", "length": 504, "header": "tr|A0A8V0YUF0-1|A0A8V0YUF0_CHICK Computationally mapped isoform of Heteroous nuclear ribonucleoprotein R OS=Gallus gallus OX=9031 GN=HNRNPR PE=1 SV=1 CANONICAL=A0A8V0YMA7-1" }, "locus": { "chromosome": "23", "start_pos": 1945565, "end_pos": 1930115, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033784.1", "url": "https://www.ensembl.org/id/ENSGALT00010033784.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019875.1", "url": "https://www.ensembl.org/id/ENSGALP00010019875.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:419570", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419570", "resource": "KEGG Pathway" }, { "id": "R-GGA-72163", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-72163", "resource": "Reactome", "description": "mRNA Splicing - Major Pathway" }, { "id": "R-GGA-9770562", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9770562", "resource": "Reactome", "description": "mRNA Polyadenylation" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A9J7K155-1", "protein_name": "Heterogeneous nuclear ribonucleoprotein Q", "gene_name": "Hnrnpr", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MANQVNGNAVQLKEEEEPMDTSSVTHTEHYKTLIEAGLPQKVAERLDEIFQTGLVAYVDLDERAIDALREFNEEGALSVLQQFKESDLSHVQNKSAFLCGVMKTYRQREKQGSKVQESTKGPDEAKIKALLERTGYTLDVTTGQRKYGGPPPDSVYSGVQPGIGTEVFVGKIPRDLYEDELVPLFEKAGPIWDLRLMMDPLSGQNRGYAFITFCGKEAAQEAVKLCDSYEIRPGKHLGVCISVANNRLFVGSIPKNKTKENILEEFSKVTGLTEGLVDVILYHQPDDKKKNRGFCFLEYEDHKSAAQARRRLMSGKVKVWGNVVTVEWADPVEEPDPEVMAKVKVLFVRNLATTVTEEILEKSFSEFGKLERVKKLKDYAFVHFEDRGAAVKAMDEMNGKEIEGEEIEIVLAKPPDKKRKERQAARQASRSTAYEDYYYHPPPRMPPPMRGRGRGGGRGGYGYPPDYYGYEDYYDDYYGYDYHDYRGGYEDPYYGYDDGYAVRGRGGGRGGRGAPPPPRGRGAPPPRGRAGYSQRGAPLGPPRGSRGGRGGPAQQQRGRGSRGARGNRGGNVGGKRKADGYNQPDSKRRQTNNQQNWGSQPIAQQPLQQGGDYSGNYGYNNDNQEFYQDTYGQQWK", "length": 636 }, "evidence": [ { "id": "A0A8V0YMA7", "url": "https://omabrowser.org/oma/group/A0A8V0YMA7/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "O43390-1", "protein_name": "Heterogeneous nuclear ribonucleoprotein R", "gene_name": "HNRNPR", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MANQVNGNAVQLKEEEEPMDTSSVTHTEHYKTLIEAGLPQKVAERLDEIFQTGLVAYVDLDERAIDALREFNEEGALSVLQQFKESDLSHVQNKSAFLCGVMKTYRQREKQGSKVQESTKGPDEAKIKALLERTGYTLDVTTGQRKYGGPPPDSVYSGVQPGIGTEVFVGKIPRDLYEDELVPLFEKAGPIWDLRLMMDPLSGQNRGYAFITFCGKEAAQEAVKLCDSYEIRPGKHLGVCISVANNRLFVGSIPKNKTKENILEEFSKVTEGLVDVILYHQPDDKKKNRGFCFLEYEDHKSAAQARRRLMSGKVKVWGNVVTVEWADPVEEPDPEVMAKVKVLFVRNLATTVTEEILEKSFSEFGKLERVKKLKDYAFVHFEDRGAAVKAMDEMNGKEIEGEEIEIVLAKPPDKKRKERQAARQASRSTAYEDYYYHPPPRMPPPIRGRGRGGGRGGYGYPPDYYGYEDYYDDYYGYDYHDYRGGYEDPYYGYDDGYAVRGRGGGRGGRGAPPPPRGRGAPPPRGRAGYSQRGAPLGPPRGSRGGRGGPAQQQRGRGSRGSRGNRGGNVGGKRKADGYNQPDSKRRQTNNQQNWGSQPIAQQPLQQGGDYSGNYGYNNDNQEFYQDTYGQQWK", "length": 633 }, "evidence": [ { "id": "A0A8V0YMA7", "url": "https://omabrowser.org/oma/group/A0A8V0YMA7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMA7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMA7" } ], "pmid": "" }, { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMA7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMA7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMA7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMA7" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMA7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMA7" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMA7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMA7" } ], "pmid": "" }, { "name": "catalytic step 2 spliceosome", "id": "GO:0071013", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071013", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMA7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMA7" } ], "pmid": "" }, { "name": "ribonucleoprotein complex", "id": "GO:1990904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990904", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMA7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMA7" } ], "pmid": "" }, { "name": "spliceosomal complex", "id": "GO:0005681", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005681", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMA7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMA7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "mRNA processing", "id": "GO:0006397", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006397", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMA7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMA7" } ], "pmid": "" }, { "name": "RNA splicing", "id": "GO:0008380", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008380", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMA7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMA7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 256, "end_pos": 258, "annotation": "n_glycosylation_sequon" }, { "start_pos": 93, "end_pos": 95, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], 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"XP_416102", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_416102" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_416102.4. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_416102", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_416102" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJG0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJG0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CAPS2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJG0", "locus": { "chromosome": "1", "start_pos": 37828554, "end_pos": 37862799, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012891", "url": "https://www.ensembl.org/id/ENSGALG00010012891" } ] } } ], "crossref": [ { "id": "A0A8V0YJG0", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YJG0", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00051", "url": 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{ "id": "A0A8V0YHG2", "url": "https://www.orthodb.org/?gene=A0A8V0YHG2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YJG0", "url": "https://www.orthodb.org/?gene=A0A8V0YJG0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR34524", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR34524", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR34524:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR34524:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13499", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13499", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_416102", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_416102", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YGE3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGE3", "database": 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"MDLEVKGIAASPRRQTQLSSRGKKCQGWRPDTRAARGPRPPEVPCLDLGRLRDSDDENGNSYIPCSRSFPHTCSLNSSLDWRTSLETPRGQHLPSQQRSVLEQKTIPENLPTPTDKYKLKYHQYEADMKEEYKQYSERTAEKKRNHLPCPGTSVEGSQFEDGHSDDLTALDEKALLQRCYTSKPYNTQHSMKKSEAEDVAAERKKQAVVEQVMLDQLSRAVISDPEQNTRGDVSKEVQGHLGLGTAPMRFRKRTLHETKIRTKSGLTENMLSNKLRFDSRIVSRNGRDACRDLIGFFFACDRSLTVYEFRQFGKNRTNALPFIQKGVYQHQRGQKKGKAYDLTDFYIGANLTFQSIDHNLPKSIKQNPILTLRVTSIDEVAMDFLKDSCLEFNQGYSEQLIDDSKVFKKIQGMLRETLSKRGVRVVTGLGKYFRHIDKNGNGFLSQTDFKEALKLFHLEVPEQDFESLWLILDDSKSDKVNYGEFIHAIAGEMNEYRKAFVRKAYMKLDFNKTGSVPMVDIRKCYCAKKHPLVLAGKATEEEIKSSFLETLGESCSSPEEVSYSEFEDYYEGLSIGIADDDDFVNILRNPWGI", "length": 593, "header": "tr|A0A8V0YJG0-1|A0A8V0YJG0_CHICK Isoform 1 of Calcyphosine 2 OS=Gallus gallus OX=9031 GN=CAPS2 PE=4 SV=1 CANONICAL=A0A8V0YJG0-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YGE3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJG0/entry#A0A8V0YGE3-1", "sequence": { "sequence": "MDLEVKGIAASPRRQTQLSSRGKKCQGWRPDTRAARGPRPPEVPCLDLGRLRDSDDENGNSYIPCSRSFPHTCSLNSSLDWRTSLETPRGQHLPSQQRSVLEQKTIPENLPTPTDKYKLKYHQYEADMKEEYKQYSERTAEKKRNHLPCPGTSVEGSQFEDGHSDDLTALDEKALLQRCYTSKPYNTQHSMKKSEAEDVAAERKKQAVVEQVMLDQLSRAVISDPEQNTRGDVSKEVQGHLGLGTAPMRFRKRTLHETKNGRDACRDLIGFFFACDRSLTVYEFRQFGKNRTNALPFIQKGVYQHQRGQKKGKAYDLTDFYIGANLTFQSIDHNLPKSIKQNPILTLRVTSIDEVAMDFLKDSCLEFNQGYSEQLIDDSKVFKKIQGMLRETLSKRGVRVVTGLGKYFRHIDKNGNGFLSQTDFKEALKLFHLEVPEQDFESLWLILDDSKSDKVNYGEFIHAIAGEMNEYRKAFVRKAYMKLDFNKTGSVPMVDIRKCYCAKKHPLVLAGKATEEEIKSSFLETLGESCSSPEEVSYSEFEDYYEGLSIGIADDDDFVNILRNPWGI", "length": 568, "header": "tr|A0A8V0YGE3-1|A0A8V0YJG0_CHICK Computationally mapped isoform of Calcyphosine 2 OS=Gallus gallus OX=9031 GN=CAPS2 PE=4 SV=1 CANONICAL=A0A8V0YJG0-1" }, "locus": { "chromosome": "1", "start_pos": 37862380, "end_pos": 37829598, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030935.1", "url": "https://www.ensembl.org/id/ENSGALT00010030935.1" }, { "database": 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"chromosome": "1", "start_pos": 37862309, "end_pos": 37829598, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030946.1", "url": "https://www.ensembl.org/id/ENSGALT00010030946.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017978.1", "url": "https://www.ensembl.org/id/ENSGALP00010017978.1" } ] } }, { "isoform_ac": "A0A8V0YJG0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJG0/entry#A0A8V0YJG0-1", "sequence": { "sequence": "MDLEVKGIAASPRRQTQLSSRGKKCQGWRPDTRAARGPRPPEVPCLDLGRLRDSDDENGNSYIPCSRSFPHTCSLNSSLDWRTSLETPRGQHLPSQQRSVLEQKTIPENLPTPTDKYKLKYHQYEADMKEEYKQYSERTAEKKRNHLPCPGTSVEGSQFEDGHSDDLTALDEKALLQRCYTSKPYNTQHSMKKSEAEDVAAERKKQAVVEQVMLDQLSRAVISDPEQNTRGDVSKEVQGHLGLGTAPMRFRKRTLHETKIRTKSGLTENMLSNKLRFDSRIVSRNGRDACRDLIGFFFACDRSLTVYEFRQFGKNRTNALPFIQKGVYQHQRGQKKGKAYDLTDFYIGANLTFQSIDHNLPKSIKQNPILTLRVTSIDEVAMDFLKDSCLEFNQGYSEQLIDDSKVFKKIQGMLRETLSKRGVRVVTGLGKYFRHIDKNGNGFLSQTDFKEALKLFHLEVPEQDFESLWLILDDSKSDKVNYGEFIHAIAGEMNEYRKAFVRKAYMKLDFNKTGSVPMVDIRKCYCAKKHPLVLAGKATEEEIKSSFLETLGESCSSPEEVSYSEFEDYYEGLSIGIADDDDFVNILRNPWGI", "length": 593, "header": "tr|A0A8V0YJG0-1|A0A8V0YJG0_CHICK Isoform 1 of Calcyphosine 2 OS=Gallus gallus OX=9031 GN=CAPS2 PE=4 SV=1 CANONICAL=A0A8V0YJG0-1" }, "locus": { "chromosome": "1", "start_pos": 37862380, "end_pos": 37829598, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030939.1", "url": "https://www.ensembl.org/id/ENSGALT00010030939.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017974.1", "url": "https://www.ensembl.org/id/ENSGALP00010017974.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJG0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJG0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 315, "end_pos": 317, "annotation": "n_glycosylation_sequon" }, { "start_pos": 350, "end_pos": 352, "annotation": "n_glycosylation_sequon" }, { "start_pos": 511, "end_pos": 513, "annotation": "n_glycosylation_sequon" }, { "start_pos": 76, "end_pos": 78, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": 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This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_416408.3. 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"A0A8V0YK42", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK42" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SLC15A5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK42", "locus": { "chromosome": "1", "start_pos": 63222428, "end_pos": 63325090, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013023", "url": "https://www.ensembl.org/id/ENSGALG00010013023" } ] } } ], "crossref": [ { "id": "A0A8V0YK42", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YK42", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd17349", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd17349", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "418177", "url": "https://www.ncbi.nlm.nih.gov/gene/418177", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000109", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000109", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036259", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036259", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:418177", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418177", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "TVNLCFI", "url": "https://omabrowser.org/oma/group/TVNLCFI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YBR1", "url": "https://www.orthodb.org/?gene=A0A8V0YBR1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YBR6", "url": "https://www.orthodb.org/?gene=A0A8V0YBR6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YH67", "url": "https://www.orthodb.org/?gene=A0A8V0YH67", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YK42", "url": "https://www.orthodb.org/?gene=A0A8V0YK42", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11654", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11654", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00854", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00854", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_416408", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_416408", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YBR1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBR1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YBR1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBR1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YBR6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBR6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YBR6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBR6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YH67", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH67", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YH67-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH67-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YK42", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK42", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YK42-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK42-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPGADSGDVQEKQLTADTEKEKNLLPGRRNHAEKLTLPEKKVQEAICVLLVELCERFTFFGIVCNMILFCTVRLGYRNYQAAIVNMCFVGTSMLTPVLAGWLAECLVGRIKLVCVCMFLHFLGTALLPIVAFPFEDIYIDKRHILLHTLTKKEQKMVFYFALLTASLGIGGIRAIVCPLSAYNLENCGPKELLSFFNWFYWLINLNSAVVFVSISYIQQSVARNLGFLLPFVSVLMAMITIHMVRGKMIYKPKTDSSLLTTFGVIGSALKTCCVRYRYFSGDVSSWLDHAKEYHGGQYSETQVESTKSLARLFPFFAFQILYRTCIMQIPSGYYLQTMNSNLNFSGFVLPIAAMNVISIVPLLILVPILECINSYLFSSKGSGHPPTMYIVAGQLCAALSVMVAGFSEIHRKHFPQVEQTLSEEVLLVSSMPCFHLAPQYILLGVAEALVTPSCSLLSFWLVPERIRGISMHFLTLFNGAGCFMGAFFVQTAHTGTQGNWFPHLLHEGKLERFFFFLASLMMVNALGFWTVAHRYSNLNQEYTSEFRGSLSEEKEVFLKHDKVIEHYGSVLDHSPILSPMETT", "length": 583, "header": "tr|A0A8V0YK42-1|A0A8V0YK42_CHICK Isoform 1 of Solute carrier family 15 member 5 OS=Gallus gallus OX=9031 GN=SLC15A5 PE=3 SV=1 CANONICAL=A0A8V0YK42-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YBR1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK42/entry#A0A8V0YBR1-1", "sequence": { "sequence": "MPGADSGDVQEKQLTADTEKEKNLLPGRRNHAEKLTLPEKKVQEAICVLLVELCERFTFFGIVCNMILFCTVRLGYRNYQAAIVNMCFVGTSMLTPVLAGWLAECLVGRIKLVCVCMFLHFLALLPIVAFPFEDIYIDKRHILLHTLTKKEQKMVFYFALLTASLGIGGIRAIVCPLSAYNLENCGPKELLSFFNWFYWLINLNSAVVFVSISYIQQSVARNLGFLLPFVSVLMAMITIHMVRGKMIYKPKTDSSLLTTFGVIGSALKTCCVRYRYFSGDVSSWLDHAKEYHGGQYSETQVESTKSLARLFPFFAFQILYRTCIMQIPSGYYLQTMNSNLNFSGFVLPIAAMNVISIVPLLILVPILECINSYLFSSKGSGHPPTMYIVAGQLCAALSVMVAGFSEIHRKHFPQVEQTLSEEVLLVSSMPCFHLAPQYILLGVAEALVTPSCSLLSFWLVPERIRGISMHFLTLFNGAGCFMGAFFVQTAHTGTQGNWFPHLLHEGKLERFFFFLASLMMVNALGFWTVAHRYSNLNQEYTSEFRGSLSEEKEVFLKHDKVIEHYGSVLDHSPILSPMETT", "length": 581, "header": "tr|A0A8V0YBR1-1|A0A8V0YBR1_CHICK Computationally mapped isoform of Solute carrier family 15 member 5 OS=Gallus gallus OX=9031 GN=SLC15A5 PE=3 SV=1 CANONICAL=A0A8V0YK42-1" }, "locus": { "chromosome": "1", "start_pos": 63303355, "end_pos": 63274766, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031238.1", "url": "https://www.ensembl.org/id/ENSGALT00010031238.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018204.1", "url": "https://www.ensembl.org/id/ENSGALP00010018204.1" } ] } }, { "isoform_ac": "A0A8V0YBR6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK42/entry#A0A8V0YBR6-1", "sequence": { "sequence": "MPGADSGDVQEKQLTADTEKEKNLLPGRRNHAEKLTLPEKKVQEAICVLLVELCERFTFFGIVCNMILFCTVRLGYRNYQAAIVNMCFVGTSMLTPVLAGWLAECLVGRIKLVCVCMFLHFLGTALLPIVAFPFEDIYIDKRHILLHTLTKKEQKMVFYFALLTASLGIGGIRAIVCPLSAYNLENCGPKELLSFFNWFYWLINLNSAVVFVSISYIQQSVARNLGFLLPFVSVLMAMITIHMVRGKMIYKPKTDSSLLTTFGVIGSALKTCCVRYRYFSGDVSSWLDHAKEYHGGQYSETQVESTKSLARLFPFFAFQILYRTCIMQIPSGYYLQTMNSNLNFSGFVLPIAAMNVISIVPLLILVPILECINSYLFSSKGSGHPPTMYIVAGQLCAALSVMVAGFSEIHRKHFPQVEQTLSEEVLLVSSMPCFHLAPQYILLGVAEALVTPSCSLLSFWLVPERIRGISMHFLTLFNGAGCFMGAFFVQTAHTGTQGNWFPHLLHEGKLERFFFFLASLMMVNALGFWTVAHSHCQVVWKCIRASHVVENLQGRKDIHGELI", "length": 563, "header": "tr|A0A8V0YBR6-1|A0A8V0YBR6_CHICK Computationally mapped isoform of Solute carrier family 15 member 5 OS=Gallus gallus OX=9031 GN=SLC15A5 PE=3 SV=1 CANONICAL=A0A8V0YK42-1" }, "locus": { "chromosome": "1", "start_pos": 63303355, "end_pos": 63222478, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031244.1", "url": "https://www.ensembl.org/id/ENSGALT00010031244.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018209.1", "url": "https://www.ensembl.org/id/ENSGALP00010018209.1" } ] } }, { "isoform_ac": "A0A8V0YH67-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK42/entry#A0A8V0YH67-1", "sequence": { "sequence": "MPGADSGDVQEKQLTADTEKEKNLLPGRRNHAEKLTLPEKKVQEAICVLLVELCERFTFFGIVCNMILFCTVRLGYRNYQAAIVNMCFVGTSMLTPVLAGWLAECLVGRIKLVCVCMFLHFLGTALLPIVAFPFEDIYIDKRHILLHTLTKKEQKMVFYFALLTASLGIGGIRAIVCPLSAYNLENCGPKELLSFFNWFYWLINLNSAVVFVSISYIQQSVARNLGFLLPFVSVLMAMITIHMVRGKMIYKPKTDSSLLTTFGVIGSALKTCCVRYRYFSGDVSSWLDHAKEYHGGQYSETQVESTKSLARLFPFFAFQILYRTCIMQIPSGYYLQTMNSNLNFSGFVLPIAAMNVISIVPLLILVPILECINSYLFSSKGSGHPPTMYIVAGQLCAALSVMVAGFSEIHRKHFPQVEQTLSEEVLLVSSMPCFHLAPQYILLGVAEALVTPSCSLLSFWLVPERIRGISMHFLTLFNGAGCFMGAFFVQTAHTGTQGNWFPHLLHEGKLERFFFFLASLMMVNALGFWTVAHRIGSDLQSYGTVNKDELMLTPQLATPSCELKPLVRPDLKIGHVGADFLVDFLFCFPFLCPVFIPPVPSNL", "length": 603, "header": "tr|A0A8V0YH67-1|A0A8V0YK42_CHICK Computationally mapped isoform of Solute carrier family 15 member 5 OS=Gallus gallus OX=9031 GN=SLC15A5 PE=3 SV=1 CANONICAL=A0A8V0YK42-1" }, "locus": { "chromosome": "1", "start_pos": 63303355, "end_pos": 63264876, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031243.1", "url": "https://www.ensembl.org/id/ENSGALT00010031243.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018208.1", "url": "https://www.ensembl.org/id/ENSGALP00010018208.1" } ] } }, { "isoform_ac": "A0A8V0YK42-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK42/entry#A0A8V0YK42-1", "sequence": { "sequence": "MPGADSGDVQEKQLTADTEKEKNLLPGRRNHAEKLTLPEKKVQEAICVLLVELCERFTFFGIVCNMILFCTVRLGYRNYQAAIVNMCFVGTSMLTPVLAGWLAECLVGRIKLVCVCMFLHFLGTALLPIVAFPFEDIYIDKRHILLHTLTKKEQKMVFYFALLTASLGIGGIRAIVCPLSAYNLENCGPKELLSFFNWFYWLINLNSAVVFVSISYIQQSVARNLGFLLPFVSVLMAMITIHMVRGKMIYKPKTDSSLLTTFGVIGSALKTCCVRYRYFSGDVSSWLDHAKEYHGGQYSETQVESTKSLARLFPFFAFQILYRTCIMQIPSGYYLQTMNSNLNFSGFVLPIAAMNVISIVPLLILVPILECINSYLFSSKGSGHPPTMYIVAGQLCAALSVMVAGFSEIHRKHFPQVEQTLSEEVLLVSSMPCFHLAPQYILLGVAEALVTPSCSLLSFWLVPERIRGISMHFLTLFNGAGCFMGAFFVQTAHTGTQGNWFPHLLHEGKLERFFFFLASLMMVNALGFWTVAHRYSNLNQEYTSEFRGSLSEEKEVFLKHDKVIEHYGSVLDHSPILSPMETT", "length": 583, "header": "tr|A0A8V0YK42-1|A0A8V0YK42_CHICK Isoform 1 of Solute carrier family 15 member 5 OS=Gallus gallus OX=9031 GN=SLC15A5 PE=3 SV=1 CANONICAL=A0A8V0YK42-1" }, "locus": { "chromosome": "1", "start_pos": 63303355, "end_pos": 63274766, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031234.1", "url": "https://www.ensembl.org/id/ENSGALT00010031234.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018202.1", "url": "https://www.ensembl.org/id/ENSGALP00010018202.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:418177", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418177", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A6NIM6-1", "protein_name": "Solute carrier family 15 member 5", "gene_name": "SLC15A5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSVTGFTITDEKVHLYHSIEKEKTVRHIGDLCSSHSVKKIQVGICLLLVELCERFTFFEVVCNMIPFCTIKLGYHNCQAAILNLCFIGTSILTPVFVRWLTDVYLGRNKLVYICLFLHFLGTALLSVVAFPLEDFYLGTYHAVNNIPKTEQHRLFYVALLTICLGIGGVRAIVCPLGAFGLQEYGSQKTMSFFNWFYWLMNLNATIVFLGISYIQHSQAWALVLLIPFMSMLMAVITLHMIYYNLIYQSEKRCSLLTGVGVLVSALKTCHPQYCHLGRDVTSQLDHAKEKNGGCYSELHVEDTTFFLTLLPLFIFQLLYRMCIMQIPSGYYLQTMNSNLNLDGFLLPIAVMNAISSLPLLILAPFLEYFSTCLFPSKRVGSFLSTCIIAGNLFAALSVMIAGFFEIHRKHFPAVEQPLSGKVLTVSSMPCFYLILQYVLLGVAETLVNPALSVISYRFVPSNVRGTSMNFLTLFNGFGCFTGALLVKLVYLISDGNWFPNTLNKGNLESFFFFLASLTLLNVLGFCSVSQRYCNLNHFNAQNIRGSNLEETLLLHEKSLKFYGSIQEFSSSIDLWETAL", "length": 579 }, "evidence": [ { "id": "A0A8V0YK42", "url": "https://omabrowser.org/oma/group/A0A8V0YK42/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "D3ZKX5-1", "protein_name": "Solute carrier family 15 member 5", "gene_name": "Slc15a5", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFVTGFIINDEKAPLPLHGGPERQKTVGHLGCFRVGICSLLVELCERFTFFEVVCNMIPFCTRRLGCYNHQAAILNLCFIGASVLTPVFMGWLSDSKYLGRNKLVYIAVFLHFLGTALLSVLAFPSEDFYGGTSPASNMPMKKRAGLFHVALLTLCLGTGGIRAVVCLPDACGHWEQESKKPMSFCNWASWSMNLNTAVVFLGVSSIQLLGSGAVMILLPSLSVFTASVTLYMTYCDLIYEPENHCSLPTVSRAFARVLKTRCLLYCHLGRAGSSWLARAMAKQGVCHCELQEEETENVFSALLSLFSFQLIYRMCLTQIPSGYYLQTMHSNRTLGGVPLPIALMNAISLLPLLTLGPFMDFFSNCLLPSKRDGPFLSVCIIAGNICAAFSVAVAGFLEIHRKLAQEQSPSGKLSSVSSMACVYLVPQYVLLGVSEVLVNPAVSTVTRRVVPSTFRRASMTCLTLFHGSAYFAGALLIELVYLISEGNWFPNTLNKGNLESFFFVLASLTLLNILGLWRVLPRCCNLNHFNAQRIHGNNCEETLLLSEKSLKFYGSTQETSSSIDLRETAF", "length": 571 }, "evidence": [ { "id": "A0A8V0YK42", "url": "https://omabrowser.org/oma/group/A0A8V0YK42/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1N3P6-1", "protein_name": "Solute carrier family 15 member 5", "gene_name": "SLC15A5", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MNLNATVVFLGISYIQYSGAWALVLLIPFMSTLTALITLYMMHYNLIYQPEKCCSPLTTFRVFVNVLKTCCLQYCHLGGGVTSWLDHAKDKNGGRCRELLVEDVKFFSNLLPLFIFQLLYKMCIMQIPSGYYLQTVNSSLNLRGSLLPVSVMNVISILPLLILAPFMEYFSTCLLPSKRDGSFLSACILAGNLCAALSVLVAGFFEIHRKHFPPVEQLLSGKAVTVSSMAWSHLVLQYVLLRVAETLVNPAFSVIHRFVPSTIRGTFMNCLTLINGFACFMGALLFESVYLISEGNWFPNTLNKGNLENFFFFLASLTLLNVLGFWSVSQRYCNLNHFNAQNTSGSNLKETLPLQEKSLKFYGSTLEFSSSIDL", "length": 374 }, "evidence": [ { "id": "A0A8V0YK42", "url": "https://omabrowser.org/oma/group/A0A8V0YK42/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q8CBB2-1", "protein_name": "Solute carrier family 15 member 5", "gene_name": "Slc15a5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPITDFIINDEKTPLVLHGGPEQWKTVGPYGCFRVGICLLLVELCERFTFFEVVCNMIPFCTGRLGSYNHQAAMLNLGFIGTSVLTPVFMGWLADEYFGRNKLMYIALSLHFLGTALLSMLAFPAENFYRGAYPVFNNTSVEEQAGLFHVALLTLCLGTGGIRAVVCPPDMCGSQERESKKPMPFCNWASWSANLNAAVVFLGISSIQPLGSGALGILLPSLSVFTALVTLYLKHCDLIYRPENRCSLLTIARAFVRALKTRCLPYCHFGRDGSSWLDHAMEKQGGHHSELQEEDTRNISALLPLFSFQILYRTCLLQIPSGYYLQTMNSNRNWGGFSLPIALMNAISLLPLLILPPFMDYFSNCLLPSKRDGPFLSACMIAGNICAASSVAMAGFLEIYRKLAREQSPSGKLFSVSSMACVCLVPQYVLLGVSEVLVNPAVSMVTHRVIPGASMAFLTLSHGSACFAGAMLIKLLYLISEGNWFPNTLDKGNLENFFFVLASLMLLNILGLWRASWRYCNLNHFNAQRIRGNRCEETLLLTEKSLKFYGSTQGASSSIDLWETAL", "length": 566 }, "evidence": [ { "id": "A0A8V0YK42", "url": "https://omabrowser.org/oma/group/A0A8V0YK42/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9SX20-1", "protein_name": "Protein NRT1/ PTR FAMILY 3.1", "gene_name": "NPF3.1", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MEEQSKNKISEEEKQLHGRPNRPKGGLITMPFIFANEICEKLAVVGFHANMISYLTTQLHLPLTKAANTLTNFAGTSSLTPLLGAFIADSFAGRFWTITFASIIYQIGMTLLTISAIIPTLRPPPCKGEEVCVVADTAQLSILYVALLLGALGSGGIRPCVVAFGADQFDESDPNQTTKTWNYFNWYYFCMGAAVLLAVTVLVWIQDNVGWGLGLGIPTVAMFLSVIAFVGGFQLYRHLVPAGSPFTRLIQVGVAAFRKRKLRMVSDPSLLYFNDEIDAPISLGGKLTHTKHMSFLDKAAIVTEEDNLKPGQIPNHWRLSTVHRVEELKSVIRMGPIGASGILLITAYAQQGTFSLQQAKTMNRHLTNSFQIPAGSMSVFTTVAMLTTIIFYDRVFVKVARKFTGLERGITFLHRMGIGFVISIIATLVAGFVEVKRKSVAIEHGLLDKPHTIVPISFLWLIPQYGLHGVAEAFMSIGHLEFFYDQAPESMRSTATALFWMAISIGNYVSTLLVTLVHKFSAKPDGSNWLPDNNLNRGRLEYFYWLITVLQAVNLVYYLWCAKIYTYKPVQVHHSKEDSSPVKEELQLSNRSLVDE", "length": 596 }, "evidence": [ { "id": "A0A8V0YK42", "url": "https://omabrowser.org/oma/group/A0A8V0YK42/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YK42", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK42" } ], "pmid": "" }, { "name": "transmembrane transport", "id": "GO:0055085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055085", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YK42", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK42" } ], "pmid": "" }, { "name": "peptide transport", "id": "GO:0015833", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015833", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YK42", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK42" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YK42", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK42" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "transmembrane transporter activity", "id": "GO:0022857", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022857", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YK42", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK42" } ], "pmid": "" }, { "name": "symporter activity", "id": "GO:0015293", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015293", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YK42", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK42" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 343, "end_pos": 345, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 343, "end_pos": 345 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YKB1-1", "uniprot_ac": "A0A8V0YKB1", "uniprot_id": "A0A8V0YKB1_CHICK", "mass": { "chemical_mass": 126260.0, "monoisotopic_mass": 126260.0 }, "refseq": {}, "gene_names": [ { "name": "MKL1", "type": "recommended", "evidence": [ { "id": "A0A8V0YKB1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKB1" } ] } ], "protein_names": [ { "name": "Myocardin related transcription factor A", "type": "synonym", "evidence": [ { "id": "A0A8V0YKB1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKB1/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKB1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKB1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MKL1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKB1", "locus": {} } ], "crossref": [ { "id": "A0A8V0YKB1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YKB1", "database": "AlphaFoldDB", "categories": [] }, { "id": "418005", "url": "https://www.ncbi.nlm.nih.gov/gene/418005", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003034", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003034", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004018", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004018", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036361", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036361", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043451", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043451", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:418005", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418005", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "NQSVRKP", "url": "https://omabrowser.org/oma/group/NQSVRKP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YBV0", "url": "https://www.orthodb.org/?gene=A0A8V0YBV0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YBX5", "url": "https://www.orthodb.org/?gene=A0A8V0YBX5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YHB4", "url": "https://www.orthodb.org/?gene=A0A8V0YHB4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YHB7", "url": "https://www.orthodb.org/?gene=A0A8V0YHB7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YI87", "url": "https://www.orthodb.org/?gene=A0A8V0YI87", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YIA5", "url": "https://www.orthodb.org/?gene=A0A8V0YIA5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YIB6", "url": "https://www.orthodb.org/?gene=A0A8V0YIB6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YK76", "url": "https://www.orthodb.org/?gene=A0A8V0YK76", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YKA2", "url": "https://www.orthodb.org/?gene=A0A8V0YKA2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YKB1", "url": "https://www.orthodb.org/?gene=A0A8V0YKB1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22793", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22793", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22793:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22793:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02037", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02037", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02755", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02755", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-3899300", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3899300", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-5663220", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5663220", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YBV0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBV0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YBV0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBV0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YBX5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBX5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YBX5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBX5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHB4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHB4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHB4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHB4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHB7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHB7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHB7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHB7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YI87", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI87", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YI87-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI87-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YIA5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIA5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YIA5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIA5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YIB6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIB6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YIB6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIB6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YK76", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK76", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YK76-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK76-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YKA2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKA2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YKA2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKA2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YKB1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKB1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YKB1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKB1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNTGCPRGLRTGGRSLASSCVSRSLEALENKEGDWRESCWHGSELGLFVGTLSKVAITKAKVDFSGVVCLPPSVIAGNGLDGGGAGENDDEPVLVSLSAAPSPQSEAVANELQELSLQPELTLSLHHGRNPNLPPLSERKNVLQLKLQQRRTREELVSQGIMPPLKSPAAFHEQRRSLERARTEDYLKRKIRSRPERSELVRMHILEETSAEPSLQAKQLKLKRARLADDLNEKIAQRPGPMELVEKNILPVESSLKEAIIVGQVNYPKVADNSSFDEDSSDALSPEQPASHESQGSVPSPMDSRICDPLPSTTGTSLAQGTSQLQISADSNETLFLPEQPPPPLPPPPLLPPSLTNGAALPAAKPPPTLIKQSQPKSASEKSQRSKKAKELKPKVKKLKYHQYIPPDQKQDKGAPPMDSSYAKILQQQQLFLQLQILNQQQQQHYNYQTILPAPPKPPGEQQTGASAPAVRNLSAAVNSTSSVSSGSSGLMRQNSNAAVGKPGPLPANLDEMKVAELKQELKLRALPVSGTKTDLIERLRAYQEQNGTAGQTTPTPKPSTAAILPKAAEVVVAFPAARLSTGPALVTTGIAPAEVVVATVTGGGVMKFGSTGSTPPVSPTPSERSQMSTGDENSATGDTFGEMVTSPLTQLTLQASPVQFLVKEESSKSASCSISAAPRSERCSTGNSRDAEVRDKDQMLQEKDKQIEELTRMLKQKQQLVEMLRLQLEQEKRAQQSLPAPAAAGEGTALASNPVAFGIQVKSENGFLSCQSAKQSSGQTDQFNPAPTSSQMDTSNPSPVPKKAVMVKQEVPATEAEPPCQSHSPQLFLGQQGSALSDLIKGTPPPTLITDSTGTHIVLTVTKQSAERQGLSPQGKAVSSCPTSQRVQSLPTKTSSQPQCQPPASTPQQPTPQQQQQQQQQPRGLNQPVRKPSSQPSSPAAPSPSQMDLEQQQQQQKQQHTSLFGPPPPPLPVPSVPLKEPPGYEEAMKQQPKTQENGCSSQQMDDLFDILIESGEISADFKDQSSPAGKEPPAAPACSSPPSSHHSSELAVPVSLGQTVPVGRLEDFLESSTGLPLLTAGHDGPEPLSLIDDLHSEMLSSSAILDHPPSPMDTSELHFAHEPAGGIALDLAEANLDSMDWLELPGGSVMSLAPLSTTAPSLFSTDFLDGHDLQLHWDSCL", "length": 1182, "header": "tr|A0A8V0YKB1-1|A0A8V0YKB1_CHICK Isoform 1 of Myocardin related transcription factor A OS=Gallus gallus OX=9031 GN=MKL1 PE=4 SV=1 CANONICAL=A0A8V0YKB1-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YBV0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKB1/entry#A0A8V0YBV0-1", "sequence": { "sequence": "MKVLQLKLQQRRTREELVSQGIMPPLKSPAAFHEQRRSLERARTEDYLKRKIRSRPERSELVRMHILEETSAEPSLQAKQLKLKRARLADDLNEKIAQRPGPMELVEKNILPVESSLKEAIIVGQVNYPKVADNSSFDEDSSDALSPEQPASHESQGSVPSPMDSRICDPLPSTTGTSLAQGTSQLQISADSNETLFLPEQPPPPLPPPPLLPPSLTNGAALPAAKPPPTLIKQSQPKSASEKSQRSKKAKELKPKVKKLKYHQYIPPDQKQDKGAPPMDSSYAKILQQQQLFLQLQILNQQQQQHYNYQTILPAPPKPPGEQQTGASAPAVRNLSAAVNSTSSVSSGSSGLMRQNSNAAVGKPGPLPANLDEMKVAELKQELKLRALPVSGTKTDLIERLRAYQEQNGTAGQTTPTPKPSTAAILPKAAEVVVAFPAARLSTGPALVTTGIAPAEVVVATVTGGGVMKFGSTGSTPPVSPTPSERSQMSTGDENSATGDTFGEMVTSPLTQLTLQASPVQFLVKEESSKSASCSISAAPRSERCSTGNSRDAEVRDKDQMLQEKDKQIEELTRMLKQKQQLVEMLRLQLEQEKRAQQSLPAPAAAGEGTALASNPVAFGIQVKSENGFLSCQSAKQSSGQTDQFNPAPTSSQMDTSNPSPVPKKAVMVKQEVPATEAEPPCQSHSPQLFLGQQGSALSDLIKGTPPPTLITDSTGTHIVLTVTKQSAERQGLSPQGKAVSSCPTSQRVQSLPTKTSSQPQCQPPASTPQQPTPQQQQQQQQQPRGLNQPVRKPSSQPSSPAAPSPSQMDLEQQQQQQKQQHTSLFGPPPPPLPVPSVPLKEPPGYEEAMKQQPKTQENGCSSQQMDDLFDILIESGEISADFKDQSSPAGKEPPAAPACSSPPSSHHSSELAVPVSLGQTVPVGRLEDFLESSTGLPLLTAGHDGPEPLSLIDDLHSEMLSSSAILDHPPSPMDTSELHFAHEPAGGIALDLAEANLDSMDWLELPGGSVMSLAPLSTTAPSLFSTDFLDGHDLQLHWDSCL", "length": 1043, "header": "tr|A0A8V0YBV0-1|A0A8V0YBV0_CHICK Computationally mapped isoform of Myocardin related transcription factor A OS=Gallus gallus OX=9031 GN=MKL1 PE=4 SV=1 CANONICAL=A0A8V0YKB1-1" }, "locus": { "chromosome": "1", "start_pos": 50098833, "end_pos": 50056178, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031299.1", "url": "https://www.ensembl.org/id/ENSGALT00010031299.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018245.1", "url": "https://www.ensembl.org/id/ENSGALP00010018245.1" } ] } }, { "isoform_ac": "A0A8V0YBX5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKB1/entry#A0A8V0YBX5-1", "sequence": { "sequence": "MCPVFHFSDWRESCWHGSELGLFVGTLSKVAITKAKVDFSGVVCLPPSVIAGNGLDGGGAGENDDEPVLVSLSAAPSPQSEAVANELQELSLQPELTLSLHHGRNPNLPPLSERKNVLQLKLQQRRTREELVSQGIMPPLKSPAAFHEQRRSLERARTEDYLKRKIRSRPERSELVRMHILEETSAEPSLQAKQLKLKRARLADDLNEKIAQRPGPMELVEKNILPVESSLKEAIIVGQVNYPKVADNSSFDEDSSDALSPEQPASHESQGSVPSPMDSRICDPLPSTTGTSLAQGTSQLQISADSNETLFLPEQPPPPLPPPPLLPPSLTNGAALPAAKPPPTLIKQSQPKSASEKSQRSKKAKELKPKVKKLKYHQYIPPDQKQDKGAPPMDSSYAKILQQQQLFLQLQILNQQQQQHYNYQTILPAPPKPPGEQQTGASAPAVRNLSAAVNSTSSVSSGSSGLMRQNSNAAVGKPGPLPANLDEMKVAELKQELKLRALPVSGTKTDLIERLRAYQEQNGTAGQTTPTPKPSTAAILPKAAEVVVAFPAARLSTGPALVTTGIAPAEVVVATVTGGGVMKFGSTGSTPPVSPTPSERSQMSTGDENSATGDTFGEMVTSPLTQLTLQASPVQFLVKEESSKSASCSISAAPRSERCSTGNSRDAEVRDKDQMLQEKDKQIEELTRMLKQKQQLVEMLRLQLEQEKRAQQSLPAPAAAGEGTALASNPVAFGIQVKSENGFLSCQSAKQSSGQTDQFNPAPTSSQMDTSNPSPVPKKAVMVKQEVPATEAEPPCQSHSPQLFLGQQGSALSDLIKGTPPPTLITDSTGTHIVLTVTKQSAERQGLSPQGKAVSSCPTSQRVQSLPTKTSSQPQCQPPASTPQQPTPQQQQQQQQQPRGLNQPVRKPSSQPSSPAAPSPSQMDLEQQQQQQKQQHTSLFGPPPPPLPVPSVPLKEPPGYEEAMKQQPKTQRFLLTSRISHPRLEKNHLRPRPAPHRPAATIPRSWRCRCRWGRRCPWGGWRTSWRAAPASRC", "length": 1033, "header": "tr|A0A8V0YBX5-1|A0A8V0YBX5_CHICK Computationally mapped isoform of Myocardin related transcription factor A OS=Gallus gallus OX=9031 GN=MKL1 PE=4 SV=1 CANONICAL=A0A8V0YKB1-1" }, "locus": { "chromosome": "1", "start_pos": 50098522, "end_pos": 50012129, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031338.1", "url": "https://www.ensembl.org/id/ENSGALT00010031338.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018275.1", "url": "https://www.ensembl.org/id/ENSGALP00010018275.1" } ] } }, { "isoform_ac": "A0A8V0YHB4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKB1/entry#A0A8V0YHB4-1", "sequence": { "sequence": "MLDKAKTLQPTYVGIVPLAETVAKQGKSCSSTYQDSYHSLREVLQLKLQQRRTREELVSQGIMPPLKSPAAFHEQRRSLERARTEDYLKRKIRSRPERSELVRMHILEETSAEPSLQAKQLKLKRARLADDLNEKIAQRPGPMELVEKNILPVESSLKEAIIVGQVNYPKVADNSSFDEDSSDALSPEQPASHESQGSVPSPMDSRICDPLPSTTGTSLAQGTSQLQISADSNETLFLPEQPPPPLPPPPLLPPSLTNGAALPAAKPPPTLIKQSQPKSASEKSQRSKKAKELKPKVKKLKYHQYIPPDQKQDKGAPPMDSSYAKILQQQQLFLQLQILNQQQQQHYNYQTILPAPPKPPGEQQTGASAPAVRNLSAAVNSTSSVSSGSSGLMRQNSNAAVGKPGPLPANLDEMKVAELKQELKLRALPVSGTKTDLIERLRAYQEQNGTAGQTTPTPKPSTAAILPKAAEVVVAFPAARLSTGPALVTTGIAPAEVVVATVTGGGVMKFGSTGSTPPVSPTPSERSQMSTGDENSATGDTFGEMVTSPLTQLTLQASPVQFLVKEESSKSASCSISAAPRSERCSTGNSRDAEVRDKDQMLQEKDKQIEELTRMLKQKQQLVEMLRLQLEQEKRAQQSLPAPAAAGEGTALASNPVAFGIQVKSENGFLSCQSAKQSSGQTDQFNPAPTSSQMDTSNPSPVPKKAVMVKQEVPATEAEPPCQSHSPQLFLGQQGSALSDLIKGTPPPTLITDSTGTHIVLTVTKQSAERQGLSPQGKAVSSCPTSQPSSQPSSPAAPSPSQMDLEQQQQQQKQQHTSLFGPPPPPLPVPSVPLKEPPGYEEAMKQQPKTQENGCSSQQMDDLFDILIESGEISADFKDQSSPAGKEPPAAPACSSPPSSHHSSELAVPVSLGQTVPVGRLEDFLESSTGLPLLTAGHDGPEPLSLIDDLHSEMLSSSAILDHPPSPMDTSELHFAHEPAGGIALDLAEANLDSMDWLELPGGSVMSLAPLSTTAPSLFSTDFLDGHDLQLHWDSCL", "length": 1037, "header": "tr|A0A8V0YHB4-1|A0A8V0YKB1_CHICK Computationally mapped isoform of Myocardin related transcription factor A OS=Gallus gallus OX=9031 GN=MKL1 PE=4 SV=1 CANONICAL=A0A8V0YKB1-1" }, "locus": { "chromosome": "1", "start_pos": 50098833, "end_pos": 50053480, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031315.1", "url": "https://www.ensembl.org/id/ENSGALT00010031315.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018259.1", "url": "https://www.ensembl.org/id/ENSGALP00010018259.1" } ] } }, { "isoform_ac": "A0A8V0YHB7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKB1/entry#A0A8V0YHB7-1", "sequence": { "sequence": "MSSLMKNVLQLKLQQRRTREELVSQGIMPPLKSPAAFHEQRRSLERARTEDYLKRKIRSRPERSELVRMHILEETSAEPSLQAKQLKLKRARLADDLNEKIAQRPGPMELVEKNILPVESSLKEAIIVGQVNYPKVADNSSFDEDSSDALSPEQPASHESQGSVPSPMDSRICDPLPSTTGTSLAQGTSQLQISADSNETLFLPEQPPPPLPPPPLLPPSLTNGAALPAAKPPPTLIKQSQPKSASEKSQRSKKAKELKPKVKKLKYHQYIPPDQKQDKGAPPMDSSYAKILQQQQLFLQLQILNQQQQQHYNYQTILPAPPKPPGEQQTGASAPAVRNLSAAVNSTSSVSSGSSGLMRQNSNAAVGKPGPLPANLDEMKVAELKQELKLRALPVSGTKTDLIERLRAYQEQNGTAGQTTPTPKPSTAAILPKAAEVVVAFPAARLSTGPALVTTGIAPAEVVVATVTGGGVMKFGSTGSTPPVSPTPSERSQMSTGDENSATGDTFGEMVTSPLTQLTLQASPVQFLVKEESSKSASCSISAAPRSERCSTGNSRDAEVRDKDQMLQEKDKQIEELTRMLKQKQQLVEMLRLQLEQEKRAQQSLPAPAAAGEGTALASNPVAFGIQVKSENGFLSCQSAKQSSGQTDQFNPAPTSSQMDTSNPSPVPKKAVMVKQEVPATEAEPPCQSHSPQLFLGQQGSALSDLIKGTPPPTLITDSTGTHIVLTVTKQSAERQGLSPQGKAVSSCPTSQRVQSLPTKTSSQPQCQPPASTPQQPTPQQQQQQQQQPRGLNQPVRKPSSQPSSPAAPSPSQMDLEQQQQQQKQQHTSLFGPPPPPLPVPSVPLKEPPGYEEAMKQQPKTQENGCSSQQMDDLFDILIESGEISADFKDQSSPAGKEPPAAPACSSPPSSHHSSELAVPVSLGQTVPVGRLEDFLESSTGLPLLTAGHDGPEPLSLIDDLHSEMLSSSAILDHPPSPMDTSELHFAHEPAGGIALDLAEANLDSMDWLELPGGSVMSLAPLSTTAPSLFSTDFLDGHDLQLHWDSCL", "length": 1048, "header": "tr|A0A8V0YHB7-1|A0A8V0YKB1_CHICK Computationally mapped isoform of Myocardin related transcription factor A OS=Gallus gallus OX=9031 GN=MKL1 PE=4 SV=1 CANONICAL=A0A8V0YKB1-1" }, "locus": { "chromosome": "1", "start_pos": 50098833, "end_pos": 50041998, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031323.1", "url": "https://www.ensembl.org/id/ENSGALT00010031323.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018264.1", "url": "https://www.ensembl.org/id/ENSGALP00010018264.1" } ] } }, { "isoform_ac": "A0A8V0YI87-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKB1/entry#A0A8V0YI87-1", "sequence": { "sequence": "MLDKAKTLQPTYVGIVPLAETVAKQGKSCSSTYQDSYHSLREVLQLKLQQRRTREELVSQGIMPPLKSPAAFHEQRRSLERARTEDYLKRKIRSRPERSELVRMHILEETSAEPSLQAKQLKLKRARLADDLNEKIAQRPGPMELVEKNILPVESSLKEAIIVGQVNYPKVADNSSFDEDSSDALSPEQPASHESQGSVPSPMDSRICDPLPSTTGTSLAQGTSQLQISADSNETLFLPEQPPPPLPPPPLLPPSLTNGAALPAAKPPPTLIKQSQPKSASEKSQRSKKAKELKPKVKKLKYHQYIPPDQKQDKGAPPMDSSYAKILQQQQLFLQLQILNQQQQQHYNYQTILPAPPKPPGEQQTGASAPAVRNLSAAVNSTSSVSSGSSGLMRQNSNAAVGKPGPLPANLDEMKVAELKQELKLRALPVSGTKTDLIERLRAYQEQNGTAGQTTPTPKPSTAAILPKAAEVVVAFPAARLSTGPALVTTGIAPAEVVVATVTGGGVMKFGSTGSTPPVSPTPSERSQMSTGDENSATGDTFGEMVTSPLTQLTLQASPVQFLVKEESSKSASCSISAAPRSERCSTGNSRDAEVRDKDQMLQEKDKQIEELTRMLKQKQQLVEMLRLQLEQEKRAQQSLPAPAAAGEGTALASNPVAFGIQVKSENGFLSCQSAKQSSGQTDQFNPAPTSSQMDTSNPSPVPKKAVMVKQEVPATEAEPPCQSHSPQLFLGQQGSALSDLIKGTPPPTLITDSTGTHIVLTVTKQSAERQGLSPQGKAVSSCPTSQRVQSLPTKTSSQPQCQPPASTPQQPTPQQQQQQQQQPRGLNQPVRKPSSQPSSPAAPSPSQMDLEQQQQQQKQQHTSLFGPPPPPLPVPSVPLKEPPGYEEAMKQQPKTQENGCSSQQMDDLFDILIESGEISADFKDQSSPAGKEPPAAPACSSPPSSHHSSELAVPVSLGQTVPVGRLEDFLESSTGLPLLTAGHDGPEPLSLIDDLHSEMLSSSAILDHPPSPMDTSELHFAHEPAGGIALDLAEANLDSMDWLELPGGSVMSLAPLSTTAPSLFSTDFLDGHDLQLHWDSCL", "length": 1083, "header": "tr|A0A8V0YI87-1|A0A8V0YKB1_CHICK Computationally mapped isoform of Myocardin related transcription factor A OS=Gallus gallus OX=9031 GN=MKL1 PE=4 SV=1 CANONICAL=A0A8V0YKB1-1" }, "locus": { "chromosome": "1", "start_pos": 50098833, "end_pos": 50053480, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031308.1", "url": "https://www.ensembl.org/id/ENSGALT00010031308.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018252.1", "url": "https://www.ensembl.org/id/ENSGALP00010018252.1" } ] } }, { "isoform_ac": "A0A8V0YIA5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKB1/entry#A0A8V0YIA5-1", "sequence": { "sequence": "MVAITKAKVDFSGVVCLPPSVIAGNGLDGGGAGENDDEPVLVSLSAAPSPQSEAVANELQELSLQPELTLSLHHGRNPNLPPLSERKNVLQLKLQQRRTREELVSQGIMPPLKSPAAFHEQRRSLERARTEDYLKRKIRSRPERSELVRMHILEETSAEPSLQAKQLKLKRARLADDLNEKIAQRPGPMELVEKNILPVESSLKEAIIVGQVNYPKVADNSSFDEDSSDALSPEQPASHESQGSVPSPMDSRICDPLPSTTGTSLAQGTSQLQISADSNETLFLPEQPPPPLPPPPLLPPSLTNGAALPAAKPPPTLIKQSQPKSASEKSQRSKKAKELKPKVKKLKYHQYIPPDQKQDKGAPPMDSSYAKILQQQQLFLQLQILNQQQQQHYNYQTILPAPPKPPGEQQTGASAPAVRNLSAAVNSTSSVSSGSSGLMRQNSNAAVGKPGPLPANLDEMKVAELKQELKLRALPVSGTKTDLIERLRAYQEQNGTAGQTTPTPKPSTAAILPKAAEVVVAFPAARLSTGPALVTTGIAPAEVVVATVTGGGVMKFGSTGSTPPVSPTPSERSQMSTGDENSATGDTFGEMVTSPLTQLTLQASPVQFLVKEESSKSASCSISAAPRSERCSTGNSRDAEVRDKDQMLQEKDKQIEELTRMLKQKQQLVEMLRLQLEQEKRAQQSLPAPAAAGEGTALASNPVAFGIQVKSENGFLSCQSAKQSSGQTDQFNPAPTSSQMDTSNPSPVPKKAVMVKQEVPATEAEPPCQSHSPQLFLGQQGSALSDLIKGTPPPTLITDSTGTHIVLTVTKQSAERQGLSPQGKAVSSCPTSQRVQSLPTKTSSQPQCQPPASTPQQPTPQQQQQQQQQPRGLNQPVRKPSSQPSSPAAPSPSQMDLEQQQQQQKQQHTSLFGPPPPPLPVPSVPLKEPPGYEEAMKQQPKTQENGCSSQQMDDLFDILIESGEISADFKDQSSPAGKEPPAAPACSSPPSSHHSSELAVPVSLGQTVPVGRLEDFLESSTGLPLLTAGHDGPEPLSLIDDLHSEMLSSSAILDHPPSPMDTSELHFAHEPAGGIALDLAEANLDSMDWLELPGGSVMSLAPLSTTAPSLFSTDFLDGHDLQLHWDSCL", "length": 1129, "header": "tr|A0A8V0YIA5-1|A0A8V0YKB1_CHICK Computationally mapped isoform of Myocardin related transcription factor A OS=Gallus gallus OX=9031 GN=MKL1 PE=4 SV=1 CANONICAL=A0A8V0YKB1-1" }, "locus": { "chromosome": "1", "start_pos": 50098833, "end_pos": 50018451, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031333.1", "url": "https://www.ensembl.org/id/ENSGALT00010031333.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018272.1", "url": "https://www.ensembl.org/id/ENSGALP00010018272.1" } ] } }, { "isoform_ac": "A0A8V0YIB6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKB1/entry#A0A8V0YIB6-1", "sequence": { "sequence": "MTCQPRLRRCFPSLPSSSRVRKCASFQVAITKAKVDFSGVVCLPPSVIAGNGLDGGGAGENDDEPVLVSLSAAPSPQSEAVANELQELSLQPELTLSLHHGRNPNLPPLSERKNVLQLKLQQRRTREELVSQGIMPPLKSPAAFHEQRRSLERARTEDYLKRKIRSRPERSELVRMHILEETSAEPSLQAKQLKLKRARLADDLNEKIAQRPGPMELVEKNILPVESSLKEAIIVGQVNYPKVADNSSFDEDSSDALSPEQPASHESQGSVPSPMDSRICDPLPSTTGTSLAQGTSQLQISADSNETLFLPEQPPPPLPPPPLLPPSLTNGAALPAAKPPPTLIKQSQPKSASEKSQRSKKAKELKPKVKKLKYHQYIPPDQKQDKGAPPMDSSYAKILQQQQLFLQLQILNQQQQQHYNYQTILPAPPKPPGEQQTGASAPAVRNLSAAVNSTSSVSSGSSGLMRQNSNAAVGKPGPLPANLDEMKVAELKQELKLRALPVSGTKTDLIERLRAYQEQNGTAGQTTPTPKPSTAAILPKAAEVVVAFPAARLSTGPALVTTGIAPAEVVVATVTGGGVMKFGSTGSTPPVSPTPSERSQMSTGDENSATGDTFGEMVTSPLTQLTLQASPVQFLVKEESSKSASCSISAAPRSERCSTGNSRDAEVRDKDQMLQEKDKQIEELTRMLKQKQQLVEMLRLQLEQEKRAQQSLPAPAAAGEGTALASNPVAFGIQVKSENGFLSCQSAKQSSGQTDQFNPAPTSSQMDTSNPSPVPKKAVMVKQEVPATEAEPPCQSHSPQLFLGQQGSALSDLIKGTPPPTLITDSTGTHIVLTVTKQSAERQGLSPQGKAVSSCPTSQRVQSLPTKTSSQPQCQPPASTPQQPTPQQQQQQQQQPRGLNQPVRKPSSQPSSPAAPSPSQMDLEQQQQQQKQQHTSLFGPPPPPLPVPSVPLKEPPGYEEAMKQQPKTQENGCSSQQMDDLFDILIESGEISADFKDQSSPAGKEPPAAPACSSPPSSHHSSELAVPVSLGQTVPVGRLEDFLESSTGLPLLTAGHDGPEPLSLIDDLHSEMLSSSAILDHPPSPMDTSELHFAHEPAGGIALDLAEANLDSMDWLELPGGSVMSLAPLSTTAPSLFSTDFLDGHDLQLHWDSCL", "length": 1155, "header": "tr|A0A8V0YIB6-1|A0A8V0YKB1_CHICK Computationally mapped isoform of Myocardin related transcription factor A OS=Gallus gallus OX=9031 GN=MKL1 PE=4 SV=1 CANONICAL=A0A8V0YKB1-1" }, "locus": { "chromosome": "1", "start_pos": 50098833, "end_pos": 50019295, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031348.1", "url": "https://www.ensembl.org/id/ENSGALT00010031348.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018282.1", "url": "https://www.ensembl.org/id/ENSGALP00010018282.1" } ] } }, { "isoform_ac": "A0A8V0YK76-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKB1/entry#A0A8V0YK76-1", "sequence": { "sequence": "MPSALLQLKLQQRRTREELVSQGIMPPLKSPAAFHEQRRSLERARTEDYLKRKIRSRPERSELVRMHILEETSAEPSLQAKQLKLKRARLADDLNEKIAQRPGPMELVEKNILPVESSLKEAIIVGQVNYPKVADNSSFDEDSSDALSPEQPASHESQGSVPSPMDSRICDPLPSTTGTSLAQGTSQLQISADSNETLFLPEQPPPPLPPPPLLPPSLTNGAALPAAKPPPTLIKQSQPKSASEKSQRSKKAKELKPKVKKLKYHQYIPPDQKQDKGAPPMDSSYAKILQQQQLFLQLQILNQQQQQHYNYQTILPAPPKPPGEQQTGASAPAVRNLSAAVNSTSSVSSGSSGLMRQNSNAAVGKPGPLPANLDEMKVAELKQELKLRALPVSGTKTDLIERLRAYQEQNGTAGQTTPTPKPSTAAILPKAAEVVVAFPAARLSTGPALVTTGIAPAEVVVATVTGGGVMKFGSTGSTPPVSPTPSERSQMSTGDENSATGDTFGEMVTSPLTQLTLQASPVQFLVKEESSKSASCSISAAPRSERCSTGNSRDAEVRDKDQMLQEKDKQIEELTRMLKQKQQLVEMLRLQLEQEKRAQQSLPAPAAAGEGTALASNPVAFGIQVKSENGFLSCQSAKQSSGQTDQFNPAPTSSQMDTSNPSPVPKKAVMVKQEVPATEAEPPCQSHSPQLFLGQQGSALSDLIKGTPPPTLITDSTGTHIVLTVTKQSAERQGLSPQGKAVSSCPTSQRVQSLPTKTSSQPQCQPPASTPQQPTPQQQQQQQQQPRGLNQPVRKPSSQPSSPAAPSPSQMDLEQQQQQQKQQHTSLFGPPPPPLPVPSVPLKEPPGYEEAMKQQPKTQENGCSSQQMDDLFDILIESGEISADFKDQSSPAGKEPPAAPACSSPPSSHHSSELAVPVSLGQTVPVGRLEDFLESSTGLPLLTAGHDGPEPLSLIDDLHSEMLSSSAILDHPPSPMDTSELHFAHEPAGGIALDLAEANLDSMDWLELPGGSVMSLAPLSTTAPSLFSTDFLDGHDLQLHWDSCL", "length": 1045, "header": "tr|A0A8V0YK76-1|A0A8V0YK76_CHICK Computationally mapped isoform of Myocardin related transcription factor A OS=Gallus gallus OX=9031 GN=MKL1 PE=4 SV=1 CANONICAL=A0A8V0YKB1-1" }, "locus": { "chromosome": "1", "start_pos": 50098833, "end_pos": 50069083, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031290.1", "url": "https://www.ensembl.org/id/ENSGALT00010031290.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018238.1", "url": "https://www.ensembl.org/id/ENSGALP00010018238.1" } ] } }, { "isoform_ac": "A0A8V0YKA2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKB1/entry#A0A8V0YKA2-1", "sequence": { "sequence": "MTLLEPEMQMTTLQSVLQLKLQQRRTREELVSQGIMPPLKSPAAFHEQRRSLERARTEDYLKRKIRSRPERSELVRMHILEETSAEPSLQAKQLKLKRARLADDLNEKIAQRPGPMELVEKNILPVESSLKEAIIVGQVNYPKVADNSSFDEDSSDALSPEQPASHESQGSVPSPMDSRICDPLPSTTGTSLAQGTSQLQISADSNETLFLPEQPPPPLPPPPLLPPSLTNGAALPAAKPPPTLIKQSQPKSASEKSQRSKKAKELKPKVKKLKYHQYIPPDQKQDKGAPPMDSSYAKILQQQQLFLQLQILNQQQQQHYNYQTILPAPPKPPGEQQTGASAPAVRNLSAAVNSTSSVSSGSSGLMRQNSNAAVGKPGPLPANLDEMKVAELKQELKLRALPVSGTKTDLIERLRAYQEQNGTAGQTTPTPKPSTAAILPKAAEVVVAFPAARLSTGPALVTTGIAPAEVVVATVTGGGVMKFGSTGSTPPVSPTPSERSQMSTGDENSATGDTFGEMVTSPLTQLTLQASPVQFLVKEESSKSASCSISAAPRSERCSTGNSRDAEVRDKDQMLQEKDKQIEELTRMLKQKQQLVEMLRLQLEQEKRAQQSLPAPAAAGEGTALASNPVAFGIQVKSENGFLSCQSAKQSSGQTDQFNPAPTSSQMDTSNPSPVPKKAVMVKQEVPATEAEPPCQSHSPQLFLGQQGSALSDLIKGTPPPTLITDSTGTHIVLTVTKQSAERQGLSPQGKAVSSCPTSQRVQSLPTKTSSQPQCQPPASTPQQPTPQQQQQQQQQPRGLNQPVRKPSSQPSSPAAPSPSQMDLEQQQQQQKQQHTSLFGPPPPPLPVPSVPLKEPPGYEEAMKQQPKTQENGCSSQQMDDLFDILIESGEISADFKDQSSPAGKEPPAAPACSSPPSSHHSSELAVPVSLGQTVPVGRLEDFLESSTGLPLLTAGHDGPEPLSLIDDLHSEMLSSSAILDHPPSPMDTSELHFAHEPAGGIALDLAEANLDSMDWLELPGGSVMSLAPLSTTAPSLFSTDFLDGHDLQLHWDSCL", "length": 1056, "header": "tr|A0A8V0YKA2-1|A0A8V0YKA2_CHICK Computationally mapped isoform of Myocardin related transcription factor A OS=Gallus gallus OX=9031 GN=MKL1 PE=4 SV=1 CANONICAL=A0A8V0YKB1-1" }, "locus": { "chromosome": "1", "start_pos": 50098833, "end_pos": 50030895, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031328.1", "url": "https://www.ensembl.org/id/ENSGALT00010031328.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018268.1", "url": "https://www.ensembl.org/id/ENSGALP00010018268.1" } ] } }, { "isoform_ac": "A0A8V0YKB1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKB1/entry#A0A8V0YKB1-1", "sequence": { "sequence": "MNTGCPRGLRTGGRSLASSCVSRSLEALENKEGDWRESCWHGSELGLFVGTLSKVAITKAKVDFSGVVCLPPSVIAGNGLDGGGAGENDDEPVLVSLSAAPSPQSEAVANELQELSLQPELTLSLHHGRNPNLPPLSERKNVLQLKLQQRRTREELVSQGIMPPLKSPAAFHEQRRSLERARTEDYLKRKIRSRPERSELVRMHILEETSAEPSLQAKQLKLKRARLADDLNEKIAQRPGPMELVEKNILPVESSLKEAIIVGQVNYPKVADNSSFDEDSSDALSPEQPASHESQGSVPSPMDSRICDPLPSTTGTSLAQGTSQLQISADSNETLFLPEQPPPPLPPPPLLPPSLTNGAALPAAKPPPTLIKQSQPKSASEKSQRSKKAKELKPKVKKLKYHQYIPPDQKQDKGAPPMDSSYAKILQQQQLFLQLQILNQQQQQHYNYQTILPAPPKPPGEQQTGASAPAVRNLSAAVNSTSSVSSGSSGLMRQNSNAAVGKPGPLPANLDEMKVAELKQELKLRALPVSGTKTDLIERLRAYQEQNGTAGQTTPTPKPSTAAILPKAAEVVVAFPAARLSTGPALVTTGIAPAEVVVATVTGGGVMKFGSTGSTPPVSPTPSERSQMSTGDENSATGDTFGEMVTSPLTQLTLQASPVQFLVKEESSKSASCSISAAPRSERCSTGNSRDAEVRDKDQMLQEKDKQIEELTRMLKQKQQLVEMLRLQLEQEKRAQQSLPAPAAAGEGTALASNPVAFGIQVKSENGFLSCQSAKQSSGQTDQFNPAPTSSQMDTSNPSPVPKKAVMVKQEVPATEAEPPCQSHSPQLFLGQQGSALSDLIKGTPPPTLITDSTGTHIVLTVTKQSAERQGLSPQGKAVSSCPTSQRVQSLPTKTSSQPQCQPPASTPQQPTPQQQQQQQQQPRGLNQPVRKPSSQPSSPAAPSPSQMDLEQQQQQQKQQHTSLFGPPPPPLPVPSVPLKEPPGYEEAMKQQPKTQENGCSSQQMDDLFDILIESGEISADFKDQSSPAGKEPPAAPACSSPPSSHHSSELAVPVSLGQTVPVGRLEDFLESSTGLPLLTAGHDGPEPLSLIDDLHSEMLSSSAILDHPPSPMDTSELHFAHEPAGGIALDLAEANLDSMDWLELPGGSVMSLAPLSTTAPSLFSTDFLDGHDLQLHWDSCL", "length": 1182, "header": "tr|A0A8V0YKB1-1|A0A8V0YKB1_CHICK Isoform 1 of Myocardin related transcription factor A OS=Gallus gallus OX=9031 GN=MKL1 PE=4 SV=1 CANONICAL=A0A8V0YKB1-1" }, "locus": { "chromosome": "1", "start_pos": 50098833, "end_pos": 50009863, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031342.1", "url": "https://www.ensembl.org/id/ENSGALT00010031342.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018278.1", "url": "https://www.ensembl.org/id/ENSGALP00010018278.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 621, "start_aa": "Thr", "end_pos": 621, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr621", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 789, "start_aa": "Thr", "end_pos": 789, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr789", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 912, "start_aa": "Thr", "end_pos": 912, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr912", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:418005", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418005", "resource": "KEGG Pathway" }, { "id": "R-GGA-3899300", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3899300", "resource": "Reactome", "description": "SUMOylation of transcription cofactors" }, { "id": "R-GGA-5663220", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5663220", "resource": "Reactome", "description": "RHO GTPases Activate Formins" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I5Y2C3-1", "protein_name": "Myocardin related transcription factor A", "gene_name": "Mrtfa", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "VDFSSVVCLPPSVIAVNGLDGGGAGENDEEPVLLSLSAAPSPQSEAVANELQELSLQPELTLGLHPGRNPNLPPLSERKNVLQLKLQQRRTREELVSQGIMPPLKSPAAFHEQRRSLERARTEDYLKRKIRSRPERSELVRMHILEETSAEPSLQAKQLKLKRARLADDLNEKIAQRPGPMELVEKNILPVESSLKEALIVGQVNYPKVADSSSFDEDSSDALSPEQPASHESQGSVPSPLESRASDLLPSATSISPTQQSQPKSASEKSQRSKKAKELKPKVKKLKYHQYIPPDQKQDKGAPAMDSSYAKILQQQQLFLQLQILNQQQQQQQQQHYNYQAILPAPPKPSGETPGSSAPTPSRSLSTSSSSSSGTPGPGGLARQNSTALAGKPGALPANLDDMKVAELKQELKLRSLPVSGTKTELIERLRAYQDQVSPAPGAPKAPATTSVLSKAGEVVVAFPAALLSTGSALVTAGLAPAEMVVATVTSNGMVKFGSTGSTPPVSPTPSERSLLSTGDENSTPGDAFGEMVTSPLTQLTLQASPLQIVKEEGARAASCCLSPGARAELEGLDKDQMLQEKDKQIEELTRMLQQKQQLVELLRLQLEQQKRAQQPAPASSPVKRESSFSSCQLSCQPQGAARAFGPGLVVPTTNHGDAQAPAPESPPVVVKQEAGPPEPDLAPASQLLLGSQGTSFLKKVSPPTLVTDSTGTHLILTVTNKSADGPGLPTGSPQQPLSQPGSPAPGPPAQMDLEHPPQPSFATPTSLLKKEPPGYEETVTQQPKQQENGSSSQHMDDLFDILIQSGEISADFKEPPSLPGKEKSPPAEAYGPPLTPQPSPLSELPQAAPPPGSPTLPGRLEDFLESSTGLPLLTSGHEGPEPLSLIDDLHSQMLSSSAILDHPPSPMDTSELHFAPEPSSGMGLDLAVGHLDSMDWLELSSGGPVLSLAPLSTTAPSLFSMDFLDGHDLQLHWDSCL", "length": 978 }, "evidence": [ { "id": "A0A8V0YKB1", "url": "https://omabrowser.org/oma/group/A0A8V0YKB1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8M9QIR6-1", "protein_name": "Myocardin related transcription factor Ab isoform X1", "gene_name": "mrtfab", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLDTNHCLHIDASSFEDQLIQNAEDKMPVSLDCDRHAYHNLKEVLQLKLQQRRTREELVSQGIMPPLKSPAAFHEQRKSLERARTEDYLKRKIRSRPERSELVRMHILEVTTETASSSVCKTNIKTSAEPSLQAKQLKLKRARLADDLNDKISHRPGPIELIHKNILPVHALIGTESPKGESSSLDEDSSDALSPDPQCSQDSPLGLGPQHSPSDMLNMNGDLSPSQFLTQAPPPLLVTSDASPPKNLTSETNISNSSRPPSGHTKSKSSTDRTYQRSKKPKDNKPKVKKLKYHQYIPPDQKNDREPPPQLDSSYAKILHQQQLFLQLQIINQQQQHYNYHTILPAPPKLATEMQQPSTNPGPAPSQTISTSTAVSSNQTGTSRQSQPTVAGAKPSTLPANLDEFKVAELKHELKLRGLTVSGTKNDLIERLKNYQEQNCGSSAAGAPAMKTVPAQLPQVSIQSGPHQHPKDTTVPISAFPLTPTTRVHSTTPPQIMRFSSTSSSPPVSPTPSDRSVTGLSPDEASCNGDVFGEMVSSPLTQLSLHPSPEQPSPIKEESLGQVQSSCSLSRLGTLPAAQPHDPCPLSPLDKDQMLQEKDKQIEELTRMLRQKQRQVEALRSQLEQGKRAAPTEPAVDTEIPMLSNGVEVKVKEEVKEEMDTSEDLQKQIQPLKKIQTQCSQQTLFKLQQIHRLQVQQQQILVDLPNLQNTQQQEVDQLKVQQEQAKTQVSQQQKTQLLQHHQKVQLLQQQKAQLLQQQQKAQLLQQQQQKAQLLQQQQRTLVQEQQKTQLHQQKKTTLLQQQQQQKLQQLIIQQSQQKQLQANLKQQQKPQNLLQSPQVSQMFVSQQSSTQITTSFPLDILKAHPTPTLVTDSNGNRYLIALTSNSVESLTGKSPQSKSNGRITLQRLQSTPIKLPSQSSTDMTTSANHSQAVREPITKKAGLHVETSSVQESSQPVSAPPSFEPFFCEESNPLNKPTSPPSFKEDICPTFDRHTLFTPSSPKPNPQPPQCLKDNVSNNQQIDDLFEILMKSGEISSGFKASQDPSLSDLHSNPPSPSPPPSPLHLSPPAHHPEPMPVPSQQLLDTQNRPCSSTGRLEDFLESTTGAPLLGVEPDSPLTLIDDLHSQMLSTSSILDHPPSPMDTSDLSFSSHPASLDFEDPALDGMDWLGIPVVTGGSNCNGGGLVLAPLSSHTPPSVFSADFLDSPDLQLHWDSCL", "length": 1217 }, "evidence": [ { "id": "A0A8V0YKB1", "url": "https://omabrowser.org/oma/group/A0A8V0YKB1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "E1BDD9-1", "protein_name": "Myocardin related transcription factor A", "gene_name": "MRTFA", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MDSLKSEGRRMSLLQHWPLESHLSPSMLEERARIYQPTCRILPLPWIVLKPGKDSRSAMCLAPYHSLREVLQLKLQQRRTREELVSQGIMPPLKSPAAFHEQRRSLERARTEDYLKRKIRSRPERSELVRMHILEETSAEPSLQAKQLKLKRARLADDLNEKIAQRPGPMELVEKNILPVESSLKEAIIVGQVNYPKVADSSSFDEDSSDALSPEQPASHESQGSVPSPLEARVSEPPPSATSVSPTQVVSQLPVGPESGETLFLAEQPPLPPSLTNGTTVPAAKPLPTLIKQSQPKSASEKSQRSKKAKELKPKVKKLKYHQYIPPDQKQDKGAPPMDSSYAKILQQQQLFLQLQILNQQQQQQQQQHYNYQTILPAPPKPAGEALGSAGGAPTRSLSATGSSSGSGAPGPSGLVRQNSTSLAGKPGALPANLDDMKVAELKQELKLRSLPVSGTKTDLIERLRAYQEQVTPASPGAPKAPATSLLPKAGEVVVAFPTARLSTGPALVAAGLAPAEVVVATVTSNGVVKFGSTGSTPPVSPTPSERSLLSTGDENSTPGDSFGEMVTSPVTQLTLQASPLQVLVKEEGPRPGACCRSPGARAELEGRDKDQMLQEKDKQIEELTRMLRQKQQLVEWLRLQLEQEKRAQQPTPTPAPAPLALGPAVKQESNLASCQLSRRPPGPELPFSPSLAAPAAPHADARALVSPAVVVKQEAVGSEPEPAPALVTLGPTVKQENSFTSCQLSRQPLGPELPFGPSLAAPAAPHAEACALAPPVVVVKQEAVPPEPEAAPAPQLLLGPQGPSLVKGVTPPPLLTDSAGTHLVLTVTKNTDSPGLASGSPQQRGQSSPSKVTLASGSLLPPPSQPRPSTQPGPKPLSQPESPAPGPPGHMDLEPPPQPLFGTPASQPKKEPPGYEEAVSQQPRRQENGSSSQQMDDLFDILIQSGEISADFKEPGKEKAPPTAACSSPLAAQPSPAAELPQAAPPPSGSPALPGRLEDFLESSTGLPLLTGGHEGPEPLSLIDDLHSQMLSSSAILDHPPSPMDTSELHFAPEPSGVGLDLADGHLDSMDWLELSSGGPVLSLAPLSTTAPSLFSTDFLDGHDLQLHWDSCL", "length": 1114 }, "evidence": [ { "id": "A0A8V0YKB1", "url": "https://omabrowser.org/oma/group/A0A8V0YKB1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q8K4J6-1", "protein_name": "Myocardin-related transcription factor A", "gene_name": "Mrtfa", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTLLEPEMLMMAVQSVLQLKLQQRRTREELVSQGIMPPLKSPAAFHEQRRSLERARTEDYLKRKIRSRPERAELVRMHILEETSAEPSLQAKQLKLKRARLADDLNEKIAQRPGPMELVEKNILPVESSLKEAIIVGQVNYPKVADSSSFDEDSSDALSPEQPASHESQGSVPSPLESRVSDPLPSATSISPTQVLSQLPMAPDPGETLFLAEQPPLPPAPLLPPSLANGSIVPTAKPAPTLIKQSQPKSASEKSQRSKKAKELKPKVKKLKYHQYIPPDQKQDKGAPAMDSSYAKILQQQQLFLQLQILNQQQQQQQQQHYNYQAILPAPPKPSAETPGSSAPTPSRSLSTSSSPSSGTPGPSGLARQSSTALAAKPGALPANLDDMKVAELKQELKLRSLPVSGTKTELIERLRAYQDQVSPAPGAPKAPATTSVLSKAGEVVVAFPAALLSTGSALVTAGLAPAEMVVATVTSNGMVKFGSTGSTPPVSPTPSERSLLSTGDENSTPGDAFGEMVTSPLTQLTLQASPLQIVKEEGARAASCCLSPGARAELEGLDKDQMLQEKDKQIEELTRMLQQKQQLVELLRLQLEQQKRAQQPAPASSPVKRESGFSSCQLSCQPQGSAHAFGSGLVVPTTNHGDTQAPAPESPPVVVKQEAGPPEPDLAPSSQLLLGSQGTSFLKRVSPPTLVTDSTGTHLILTVTNKSADGPGLPAGSPQQPLSQPGSPAPGPPAQMDLEHPPQPPFATPTSLLKKEPPGYEETVTQQPKQQENGSSSQHMDDLFDILIQSGEISADFKEPPSLPGKEKSPPAAAAYGPPLTPQPSPLSELPQAAPPPGSPTLPGRLEDFLESSTGLPLLTSGHEGPEPLSLIDDLHSQMLSSSAILDHPPSPMDTSELHFAPEPSSGMGLDLAVGHLDSMDWLELSSGGPVLSLAPLSTAAPSLFSMDFLDGHDLQLHWDSCL", "length": 964 }, "evidence": [ { "id": "A0A8V0YKB1", "url": "https://omabrowser.org/oma/group/A0A8V0YKB1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q969V6-1", "protein_name": "Myocardin-related transcription factor A", "gene_name": "MRTFA", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPPLKSPAAFHEQRRSLERARTEDYLKRKIRSRPERSELVRMHILEETSAEPSLQAKQLKLKRARLADDLNEKIAQRPGPMELVEKNILPVESSLKEAIIVGQVNYPKVADSSSFDEDSSDALSPEQPASHESQGSVPSPLEARVSEPLLSATSASPTQVVSQLPMGRDSREMLFLAEQPPLPPPPLLPPSLTNGTTIPTAKSTPTLIKQSQPKSASEKSQRSKKAKELKPKVKKLKYHQYIPPDQKQDRGAPPMDSSYAKILQQQQLFLQLQILNQQQQQHHNYQAILPAPPKSAGEALGSSGTPPVRSLSTTNSSSSSGAPGPCGLARQNSTSLTGKPGALPANLDDMKVAELKQELKLRSLPVSGTKTELIERLRAYQDQISPVPGAPKAPAATSILHKAGEVVVAFPAARLSTGPALVAAGLAPAEVVVATVASSGVVKFGSTGSTPPVSPTPSERSLLSTGDENSTPGDTFGEMVTSPLTQLTLQASPLQILVKEEGPRAGSCCLSPGGRAELEGRDKDQMLQEKDKQIEALTRMLRQKQQLVERLKLQLEQEKRAQQPAPAPAPLGTPVKQENSFSSCQLSQQPLGPAHPFNPSLAAPATNHIDPCAVAPGPPSVVVKQEALQPEPEPVPAPQLLLGPQGPSLIKGVAPPTLITDSTGTHLVLTVTNKNADSPGLSSGSPQQPSSQPGSPAPAPSAQMDLEHPLQPLFGTPTSLLKKEPPGYEEAMSQQPKQQENGSSSQQMDDLFDILIQSGEISADFKEPPSLPGKEKPSPKTVCGSPLAAQPSPSAELPQAAPPPPGSPSLPGRLEDFLESSTGLPLLTSGHDGPEPLSLIDDLHSQMLSSTAILDHPPSPMDTSELHFVPEPSSTMGLDLADGHLDSMDWLELSSGGPVLSLAPLSTTAPSLFSTDFLDGHDLQLHWDSCL", "length": 931 }, "evidence": [ { "id": "A0A8V0YKB1", "url": "https://omabrowser.org/oma/group/A0A8V0YKB1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "transcription coactivator activity", "id": "GO:0003713", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003713", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKB1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKB1" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKB1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKB1" } ], "pmid": "" }, { "name": "actin monomer binding", "id": "GO:0003785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003785", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKB1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKB1" } ], "pmid": "" }, { "name": "transcription cis-regulatory region binding", "id": "GO:0000976", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000976", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKB1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKB1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKB1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKB1" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKB1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKB1" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKB1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKB1" } ], "pmid": "" }, { "name": "nuclear membrane", "id": "GO:0031965", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031965", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKB1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKB1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKB1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKB1" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKB1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKB1" } ], "pmid": "" }, { "name": "actin cytoskeleton organization", "id": "GO:0030036", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030036", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKB1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKB1" } ], "pmid": "" }, { "name": "smooth muscle cell differentiation", "id": "GO:0051145", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051145", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKB1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKB1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 273, "end_pos": 275, "annotation": "n_glycosylation_sequon" }, { "start_pos": 332, "end_pos": 334, "annotation": "n_glycosylation_sequon" }, { "start_pos": 473, "end_pos": 475, "annotation": "n_glycosylation_sequon" }, { "start_pos": 479, "end_pos": 481, "annotation": "n_glycosylation_sequon" }, { "start_pos": 547, "end_pos": 549, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YKB1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKB1" }, { "id": "PS50800", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50800" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SAP", "eco_id": "ECO_0000259", "start_pos": 510, "end_pos": 544, "start_aa": "Leu", "end_aa": "Gln", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 621, 789, 912 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 273, "end_pos": 275 }, { "start_pos": 332, "end_pos": 334 }, { "start_pos": 473, "end_pos": 475 }, { "start_pos": 479, "end_pos": 481 }, { "start_pos": 547, "end_pos": 549 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 3 }, { "field": "total_sites", "count": 3 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 3 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 3 }, { "field": "exact_o_linked_sites", "count": 3 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 3 }, { "field": "total_sites", "count": 3 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 3 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 3 }, { "field": "exact_o_linked_sites", "count": 3 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YKC6-1", "uniprot_ac": "A0A8V0YKC6", "uniprot_id": "A0A8V0YKC6_CHICK", "mass": { "chemical_mass": 85315.0, "monoisotopic_mass": 85315.0 }, "refseq": {}, "gene_names": [ { "name": "NCOA5", "type": "recommended", "evidence": [ { "id": "A0A8V0YKC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKC6" } ] } ], "protein_names": [ { "name": "Nuclear receptor coactivator 5", "type": "synonym", "evidence": [ { "id": "A0A8V0YKC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKC6/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKC6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKC6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "NCOA5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKC6", "locus": { "chromosome": "20", "start_pos": 10946346, "end_pos": 10965621, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013081", "url": "https://www.ensembl.org/id/ENSGALG00010013081" } ] } } ], "crossref": [ { "id": "A0A8V0YKC6", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YKC6", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000007009", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000007009", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd12341", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12341", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "419304", "url": "https://www.ncbi.nlm.nih.gov/gene/419304", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000504", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000504", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012677", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012677", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036621", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036621", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052600", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052600", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PMEEGVR", "url": "https://omabrowser.org/oma/group/PMEEGVR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YHD9", "url": "https://www.orthodb.org/?gene=A0A8V0YHD9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YKC6", "url": "https://www.orthodb.org/?gene=A0A8V0YKC6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1C9I7", "url": "https://www.orthodb.org/?gene=E1C9I7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23295", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23295", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23295:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23295:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00076", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00076", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YHD9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHD9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHD9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHD9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YKC6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKC6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YKC6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKC6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C9I7", "url": "https://www.uniprot.org/uniprotkb/E1C9I7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C9I7-1", "url": "https://www.uniprot.org/uniprotkb/E1C9I7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRPMKRCCSATLLHSRTSSEPCPKSWIWNESKMARGRKSNSIKQSDFTNSTNPQDLERRLFVGNLPTDHMTREEMEEIFSKYGKIRALSMYHGYGFVQYDRLEDVQAALDGEKGRLYKGYRLDINKAAERRNMNKASSRSSPARREPYAYGDGRDNRRDRSPLRGSPRRDPRDGRDGRNGRDSRDTRDIRARDIRDARDHRDPRDLRDLRDPRDIRDPRDLRDPRDVRDFRDPREPLYDRYRDPRDMRNPRDMRDPRDMRDPRDMRDPRDPLYRRDEPYDRYLRMDDYYRRKDDSYYDRYKEHFDRAPVNSEDRLKREERRREELYRQYYEEIKRRFDAERPVDCSVIVVDKQTKEYAESVGRKVRDLGMVVDLIFLNTELLLTQALDDVSRGGSPFAIVITQQHQVHRSCTVNIMFGTPQEHRNMPQADAMVLVARNYERYKAETREKEREEIARQAAKMADEAILQERERPPPMEEGARGGHPHPPGIQTLLNLLADNRYLTAEETDKVINYLRDRKERLLRGSTDSLQAPMSRPSLGAPSAPSLGSQSSLPSSQTHQGSQPLVSAPSVPASSANPQQELQAKILSLFNSGAAAAAVANSSSAPTVGTSGGTPSQNFTNMTSNQARSAQMSAGNLNQAQQRLQTPNTQLPSLQGPSRNAGPRPGAPPPAQSLYGQHQNRLPAPGSVPAQRPVSSGINFDNPSVQKALDTLIQSGPALSHLVSQTVAQGRAGSSTQQPMGSYQRHY", "length": 747, "header": "tr|A0A8V0YKC6-1|A0A8V0YKC6_CHICK Isoform 1 of Nuclear receptor coactivator 5 OS=Gallus gallus OX=9031 GN=NCOA5 PE=1 SV=1 CANONICAL=A0A8V0YKC6-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YHD9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKC6/entry#A0A8V0YHD9-1", "sequence": { "sequence": "MARGRKSNSIKQSDFTNSTNPQDLERRLFVGNLPTDHMTREEMEEIFSKYGKIRDINKAAERRNMNKASSRSSPARREPYAYGDGRDNRRDRSPLRGSPRRDPRDGRDGRNGRDSRDTRDIRARDIRDARDHRDPRDLRDLRDPRDIRDPRDLRDPRDVRDFRDPREPLYDRYRDPRDMRNPRDMRDPRDMRDPRDMRDPRDPLYRRDEPYDRYLRMDDYYRRKDDSYYDRYKEHFDRAPVNSEDRLKREERRREELYRQYYEEIKRRFDAERPVDCSVIVVDKQTKEYAESVGRKVRDLGMVVDLIFLNTELLLTQALDDVSRGGSPFAIVITQQHQVHRSCTVNIMFGTPQEHRNMPQADAMVLVARNYERYKAETREKEREEIARQAAKMADEAILQERERPPPMEEGARGGHPHPPGIQTLLNLLADNRYLTAEETDKVINYLRDRKERLLRGSTDSLQAPMSRPSLGAPSAPSLGSQSSLPSSQTHQGSQPLVSAPSVPASSANPQQELQAKILSLFNSGAAAAAVANSSSAPTVGTSGGTPSQNFTNMTSNQARSAQMSAGNLNQAQQRLQTPNTQLPSLQGPSRNAGPRPGAPPPAQSLYGQHQNRLPAPGSVPAQRPVSSGINFDNPSVQKALDTLIQSGPALSHLVSQTVAQGRAGSSTQQPMGSYQRHY", "length": 679, "header": "tr|A0A8V0YHD9-1|A0A8V0YKC6_CHICK Computationally mapped isoform of Nuclear receptor coactivator 5 OS=Gallus gallus OX=9031 GN=NCOA5 PE=1 SV=1 CANONICAL=A0A8V0YKC6-1" }, "locus": { "chromosome": "20", "start_pos": 10960509, "end_pos": 10947663, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031356.1", "url": "https://www.ensembl.org/id/ENSGALT00010031356.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018289.1", "url": "https://www.ensembl.org/id/ENSGALP00010018289.1" } ] } }, { "isoform_ac": "A0A8V0YKC6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKC6/entry#A0A8V0YKC6-1", "sequence": { "sequence": "MRPMKRCCSATLLHSRTSSEPCPKSWIWNESKMARGRKSNSIKQSDFTNSTNPQDLERRLFVGNLPTDHMTREEMEEIFSKYGKIRALSMYHGYGFVQYDRLEDVQAALDGEKGRLYKGYRLDINKAAERRNMNKASSRSSPARREPYAYGDGRDNRRDRSPLRGSPRRDPRDGRDGRNGRDSRDTRDIRARDIRDARDHRDPRDLRDLRDPRDIRDPRDLRDPRDVRDFRDPREPLYDRYRDPRDMRNPRDMRDPRDMRDPRDMRDPRDPLYRRDEPYDRYLRMDDYYRRKDDSYYDRYKEHFDRAPVNSEDRLKREERRREELYRQYYEEIKRRFDAERPVDCSVIVVDKQTKEYAESVGRKVRDLGMVVDLIFLNTELLLTQALDDVSRGGSPFAIVITQQHQVHRSCTVNIMFGTPQEHRNMPQADAMVLVARNYERYKAETREKEREEIARQAAKMADEAILQERERPPPMEEGARGGHPHPPGIQTLLNLLADNRYLTAEETDKVINYLRDRKERLLRGSTDSLQAPMSRPSLGAPSAPSLGSQSSLPSSQTHQGSQPLVSAPSVPASSANPQQELQAKILSLFNSGAAAAAVANSSSAPTVGTSGGTPSQNFTNMTSNQARSAQMSAGNLNQAQQRLQTPNTQLPSLQGPSRNAGPRPGAPPPAQSLYGQHQNRLPAPGSVPAQRPVSSGINFDNPSVQKALDTLIQSGPALSHLVSQTVAQGRAGSSTQQPMGSYQRHY", "length": 747, "header": "tr|A0A8V0YKC6-1|A0A8V0YKC6_CHICK Isoform 1 of Nuclear receptor coactivator 5 OS=Gallus gallus OX=9031 GN=NCOA5 PE=1 SV=1 CANONICAL=A0A8V0YKC6-1" }, "locus": { "chromosome": "20", "start_pos": 10965398, "end_pos": 10947663, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031361.1", "url": "https://www.ensembl.org/id/ENSGALT00010031361.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018293.1", "url": "https://www.ensembl.org/id/ENSGALP00010018293.1" } ] } }, { "isoform_ac": "E1C9I7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKC6/entry#E1C9I7-1", "sequence": { "sequence": "MARGRKSNSIKQSDFTNSTNPQDLERRLFVGNLPTDHMTREEMEEIFSKYGKIRALSMYHGYGFVQYDRLEDVQAALDGEKGRLYKGYRLDINKAAERRNMNKASSRSSPARREPYAYGDGRDNRRDRSPLRGSPRRDPRDGRDGRNGRDSRDTRDIRARDIRDARDHRDPRDLRDLRDPRDIRDPRDLRDPRDVRDFRDPREPLYDRYRDPRDMRNPRDMRDPRDMRDPRDMRDPRDPLYRRDEPYDRYLRMDDYYRRKDDSYYDRYKEHFDRAPVNSEDRLKREERRREELYRQYYEEIKRRFDAERPVDCSVIVVDKQTKEYAESVGRKVRDLGMVVDLIFLNTELLLTQALDDVSRGGSPFAIVITQQHQVHRSCTVNIMFGTPQEHRNMPQADAMVLVARNYERYKAETREKEREEIARQAAKMADEAILQERERPPPMEEGARGGHPHPPGIQTLLNLLADNRYLTAEETDKVINYLRDRKERLLRGSTDSLQAPMSRPSLGAPSAPSLGSQSSLPSSQTHQGSQPLVSAPSVPASSANPQQELQAKILSLFNSGAAAAAVANSSSAPTVGTSGGTPSQNFTNMTSNQARSAQMSAGNLNQAQQRLQTPNTQLPSLQGPSRNAGPRPGAPPPAQSLYGQHQNRLPAPGSVPAQRPVSSGINFDNPSVQKALDTLIQSGPALSHLVSQTVAQGRAGSSTQQPMGSYQRHY", "length": 715, "header": "tr|E1C9I7-1|E1C9I7_CHICK Computationally mapped isoform of Nuclear receptor coactivator 5 OS=Gallus gallus OX=9031 GN=NCOA5 PE=1 SV=2 CANONICAL=A0A8V0YKC6-1" }, "locus": { "chromosome": "20", "start_pos": 10960509, "end_pos": 10947663, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031358.1", "url": "https://www.ensembl.org/id/ENSGALT00010031358.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018290.1", "url": "https://www.ensembl.org/id/ENSGALP00010018290.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 614, "start_aa": "Thr", "end_pos": 614, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr614", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A3Q1M1S1-1", "protein_name": "Nuclear receptor coactivator 5", "gene_name": "NCOA5", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MNTAPSRPSPTRRDPYGFGDSRDTRRDRSPIRGSPRREPRDGRNGRDARDGRDMRDPRDLRDHRDSRDIRDHRDSRSMRDARDMRDLRDFRDLRETRNFRDHRDPMYDRYREMRDSRDPILRREGSYDRYLRMDDYCRRKDDAYFDRYRDSFDGRGPPGPESQSRVKERLKREERRREELYRQYFEEIQRRFDAERPVDCSVIVVNKQTKDYAESVGRKVRDLGMVVDLIFLNTEVSLSQALEDVSRGGSPFAIVITQQHQIHRSCTVNIMFGTPQEHRNMPQADAMVLVARNYERYKNECREKEREEIARQAAKMADEAILQERERGGPEEGMRGGHPPAIQSLLNLLADNRYLTAEETDKIINYLRERKERLMRSSTDSLPGPISRQPLGATSGASLKTQPSSQPLQSGQVLPSATPTPAAPPTSQQELQAKILSLFNSGTVAANSGSASPSVAAGNTQNQNFSTAANSQPQQRSQASGNQPPSILGQAGSARNMGPRPGAPSQGLFGQPSTLLAPASNLASQRPVSSTSINFDNPSVQKALDTLIQSGPALSHLVSQTTAQVRQPQAPLGSFQRHY", "length": 579 }, "evidence": [ { "id": "A0A8V0YKC6", "url": "https://omabrowser.org/oma/group/A0A8V0YKC6/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "D3ZEI6-1", "protein_name": "Nuclear receptor coactivator 5", "gene_name": "Ncoa5", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MNTAPSRPSPTRRDPYSFGDSRDTRRDRSPIRGSPRREPRDGRNGRDTRDRDIRDPRELRDRRDSRDIRDHRDSRSVREARDLRDFRDFRDLRDSRDFRDHRDPVYDRYREIRDSRDPLYRREGSYDRYLRVDDYCRRKDDSYFDRYRDSFDGRGPPGPESQSRAKERLKREERRREELYRRYFEEIQRRFDAERPVDCSVIVVNKQTKDYAESVGRKVRDLGMVVDLIFLNTEVSLSQALEDVSRGGSPFAIVITQQHQIHRSCTVNIMFGTPQEHRNMPQADAMVLVARNYERYKNDCREKEREEIARQAAKMANDAILQERDRGGPEEGGRGGHPPAIQSLINLLADNRYLTAEETDKIINYLRERKERLLRSSADSLPGPISRQPLGAASGSSLKTQPSSQPLQSGQVLPSATPTPAAPPTSQQELQAKILSLFNSGAVAANSSSASPSVATGSSQNQNFSTAANSQPQQRPQASGNQPPNIVGQAGSARNMGPRPGAPSQGLFGQPSSRLAPASNMASQRPVSSTGINFDNPSVQKALDTLIQSGPALSHLVSQTAAQVGRPQAPMGSYQRHY", "length": 578 }, "evidence": [ { "id": "A0A8V0YKC6", "url": "https://omabrowser.org/oma/group/A0A8V0YKC6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1SC53-1", "protein_name": "Nuclear receptor coactivator 5", "gene_name": "NCOA5", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MNTAPSRPSPTRRDPYGFGDSRDTRRDRSPIRGSPRREPRDGRNGRDARDSRDMRDMRDMRDPRDLRDHRDSRDMRDHRDSRSMRDARDLRDLRDFRDLRDSRDFRDHRDPMYDRYRDMRDSRDPMYRREGSYDRYLRMDDYCRRKDDSYFDRYRDSFDGRGPPGPENQSRAKERLKREERRREELYRQYFEEIQRRFDAERPVDCSVIVVNKQTKDYAESVGRKVRDLGMVVDLIFLNTEVSLSQALEDVSRGGSPFAIVITQQHQIHRSCTVNIMFGTPQEHRNMPQADAMVLVARNYERYKNECREKEREEIARQAAKMADEAILQERERGGPDEGMRGGHPPAIQSLINLLADNRYLTAEETDKIINYLRERKERLMRSSTDSLPGPISRQPLGASSGASLKTQPSSQPLQSGQVLPSATPTPAAAPTSQQELQAKILSLFNSGTVAANSSSASPSVAAGNTQNQNFSTAANSQPQQRSQASGNQPPNILGQAGSARNMGPRPGAPSQGLFGQPSTRLAPASNLASQRPVSSTAINFDNPSVQKALDTLIQSGPALSHLVSQTTAQVGRPQAPMGSYQRHY", "length": 585 }, "evidence": [ { "id": "A0A8V0YKC6", "url": "https://omabrowser.org/oma/group/A0A8V0YKC6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3H8U6-1", "protein_name": "Nuclear receptor coactivator 5", "gene_name": "Ncoa5", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MNTAPSRPSPTRRDPYGFGDSRDTRRDRSPIRGSPRREPRDGRNGRDARDSRDIRDPRELRDHRDSRDIRDHRDSRSIRDARDLRDFRDFRDLRDSRDFRDHRDPVYDRYRDIRDSRDPLYRREGSYDRYLRMDDYYRRKDDSYFDRYRDSFDGRGPRAKERLKREERRREELYRQYFEEIQRRFDAERPVDCSVIVVNKQTKDYAESVGRKVRDLGMVVDLIFLNTEVSLSQALEDVSRGGSPFAIVITQQHQIHRSCTVNIMFGTPQEHRNMPQADAMVLVARNYERYKNNCREKEREEIARQAAKMANEAILQERDRGGPEEGGRGGHPPAIQSLINLLADNRYLTAEETDRVIDYLRGRKERLLRSSAADALPGPISRQPLGAASGTSLKTQSSSQPLQSGQVLPSATPTPAAPPTSQQELQAKILSLFNSGTVSANSSSASPSVAAGSSQNQNFSTAANSQPQQRPQASGNQPPSIVGQAGSARNMGPRPGAPSQGLFGQPSSRLAPASNMASQRPVSSTGINFDNPSVQKALDTLIQSGPALSHLVSQTAAQVGRPQAPIGSYQRHY", "length": 573 }, "evidence": [ { "id": "A0A8V0YKC6", "url": "https://omabrowser.org/oma/group/A0A8V0YKC6/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q91W39-1", "protein_name": "Nuclear receptor coactivator 5", "gene_name": "Ncoa5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNTAPSRPSPTRRDPYSFGDSRDTRRDRSPIRGSPRREPRDGRNGRDARDSRDIRDPRDLRDRRDSRDIRDHRDSRSVREARDLRDFRDFRDLRDSRDFRDHRDPVYDRYRDIRDSRDPLYRREGSYDRYLRVDDYCRRKDDSYFDRYRDSFDGRGPPGPESQSRAKERLKREERRREELYRRYFEEIQRRFDAERPVDCSVIVVNKQTKDYAESVGRKVRDLGMVVDLIFLNTEVSLSQALEDVSRGGSPFAIVITQQHQIHRSCTVNIMFGTPQEHRNMPQADAMVLVARNYERYKNDCREKEREEIARQAAKMANDAILQERDRGGPEEGGRGGHPPAIQSLINLLADNRYLTAEETDKIINYLRERKERLLRSSADSLPGPISRQPLGAASGSSLKSQPSSQPLQSGQVLPSATPTPAAPPTSQQELQAKILSLFNSGAVAANSSSASPSVATGSSQNQNFSTAANSQPQQRPQASGNQPPNIVGQAGSARNMGPRPGAPSQGLFGQPSSRLAPASTMASQRPVSSTGINFDNPSVQKALDTLIQSGPALSHLVSQTAAQVGRPQAPMGSYQRHY", "length": 579 }, "evidence": [ { "id": "A0A8V0YKC6", "url": "https://omabrowser.org/oma/group/A0A8V0YKC6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9HCD5-1", "protein_name": "Nuclear receptor coactivator 5", "gene_name": "NCOA5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNTAPSRPSPTRRDPYGFGDSRDSRRDRSPIRGSPRREPRDGRNGRDARDSRDIRDPRDLRDHRHSRDLRDHRDSRSVRDVRDVRDLRDFRDLRDSRDFRDQRDPMYDRYRDMRDSRDPMYRREGSYDRYLRMDDYCRRKDDSYFDRYRDSFDGRGPPGPESQSRAKERLKREERRREELYRQYFEEIQRRFDAERPVDCSVIVVNKQTKDYAESVGRKVRDLGMVVDLIFLNTEVSLSQALEDVSRGGSPFAIVITQQHQIHRSCTVNIMFGTPQEHRNMPQADAMVLVARNYERYKNECREKEREEIARQAAKMADEAILQERERGGPEEGVRGGHPPAIQSLINLLADNRYLTAEETDKIINYLRERKERLMRSSTDSLPGPISRQPLGATSGASLKTQPSSQPLQSGQVLPSATPTPSAPPTSQQELQAKILSLFNSGTVTANSSSASPSVAAGNTPNQNFSTAANSQPQQRSQASGNQPPSILGQGGSAQNMGPRPGAPSQGLFGQPSSRLAPASNMTSQRPVSSTGINFDNPSVQKALDTLIQSGPALSHLVSQTTAQMGQPQAPMGSYQRHY", "length": 579 }, "evidence": [ { "id": "A0A8V0YKC6", "url": "https://omabrowser.org/oma/group/A0A8V0YKC6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKC6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKC6" } ], "pmid": "" }, { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKC6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKC6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKC6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKC6" } ], "pmid": "" }, { "name": "actin cytoskeleton", "id": "GO:0015629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015629", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKC6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKC6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "regulation of signal transduction", "id": "GO:0009966", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009966", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKC6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKC6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 29, "end_pos": 31, "annotation": "n_glycosylation_sequon" }, { "start_pos": 49, "end_pos": 51, "annotation": "n_glycosylation_sequon" }, { "start_pos": 601, "end_pos": 603, "annotation": "n_glycosylation_sequon" }, { "start_pos": 618, "end_pos": 620, "annotation": "n_glycosylation_sequon" }, { "start_pos": 621, "end_pos": 623, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YKC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKC6" }, { "id": "PS50102", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50102" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RRM", "eco_id": "ECO_0000259", "start_pos": 58, "end_pos": 129, "start_aa": "Arg", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 614 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 29, "end_pos": 31 }, { "start_pos": 49, "end_pos": 51 }, { "start_pos": 601, "end_pos": 603 }, { "start_pos": 618, "end_pos": 620 }, { "start_pos": 621, "end_pos": 623 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YIL8-1", "uniprot_ac": "A0A8V0YIL8", "uniprot_id": "A0A8V0YIL8_CHICK", "mass": { "chemical_mass": 117347.0, "monoisotopic_mass": 117347.0 }, "refseq": { "ac": "XP_025004749", "name": "liprin-beta-1 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025004749" }, "gene_names": [ { "name": "PPFIBP1", "type": "recommended", "evidence": [ { "id": "A0A8V0YIL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIL8" } ] }, { "name": "PPFIBP1", "type": "synonym", "evidence": [ { "id": "XP_025004749", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025004749" } ] }, { "name": "liprin-beta-1", "type": "synonym", "evidence": [ { "id": "XP_025004749", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025004749" } ] } ], "protein_names": [ { "name": "PPFIA binding protein 1", "type": "synonym", "evidence": [ { "id": "A0A8V0YIL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIL8/entry#names_and_taxonomy" } ] }, { "name": "liprin-beta-1 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_025004749", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025004749" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_025004749.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_025004749", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025004749" } ] }, { "annotation": "May regulate the disassembly of focal adhesions. Did not bind receptor-like tyrosine phosphatases type 2A.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YC71", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC71#function" }, { "database": "UniProtKB", "id": "ARBA00060046", "url": "https://www.uniprot.org/uniprotkb/ARBA00060046#function" }, { "database": "UniProtKB", "id": "A0A8V0YIJ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIJ8#function" }, { "database": "UniProtKB", "id": "A0A8V0YQD2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQD2#function" }, { "database": "UniProtKB", "id": "A0A8V0YC68", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC68#function" }, { "database": "UniProtKB", "id": "A0A8V0YC80", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC80#function" }, { "database": "UniProtKB", "id": "A0A8V0YHN0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHN0#function" }, { "database": "UniProtKB", "id": "A0A8V0YHP7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHP7#function" }, { "database": "UniProtKB", "id": "A0A8V0YQG1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQG1#function" }, { "database": "UniProtKB", "id": "A0A8V0YIL8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIL8#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIL8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIL8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PPFIBP1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIL8", "locus": { "chromosome": "1", "start_pos": 68374776, "end_pos": 68275098, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013123", "url": "https://www.ensembl.org/id/ENSGALG00010013123" } ] } } ], "crossref": [ { "id": "A0A8V0YIL8", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YIL8", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd09563", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09563", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd09566", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09566", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd09569", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09569", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "418219", "url": "https://www.ncbi.nlm.nih.gov/gene/418219", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001660", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001660", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013761", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013761", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029515", "url": 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Classification" ] }, { "id": "A0A8V0YC71", "url": "https://www.orthodb.org/?gene=A0A8V0YC71", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YC80", "url": "https://www.orthodb.org/?gene=A0A8V0YC80", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YHN0", "url": "https://www.orthodb.org/?gene=A0A8V0YHN0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YHP7", "url": "https://www.orthodb.org/?gene=A0A8V0YHP7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YIJ8", "url": "https://www.orthodb.org/?gene=A0A8V0YIJ8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YIL8", "url": "https://www.orthodb.org/?gene=A0A8V0YIL8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YQD2", "url": "https://www.orthodb.org/?gene=A0A8V0YQD2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YQG1", "url": "https://www.orthodb.org/?gene=A0A8V0YQG1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12587", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12587", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12587:SF16", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12587:SF16", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00536", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00536", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07647", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07647", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF26022", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF26022", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-388844", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-388844", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_025004749", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025004749", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YC68", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC68", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YC68-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC68-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YC71", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC71", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YC71-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC71-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YC80", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC80", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YC80-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC80-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHN0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHN0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHN0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHN0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHP7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHP7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHP7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHP7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YIJ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIJ8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YIJ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIJ8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YIL8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIL8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YIL8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIL8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQD2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQD2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQD2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQD2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQG1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQG1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQG1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQG1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MMSDASDMLAAALEQMDGIIAGSKALEYSNGIFDCQSPTSPFMGGLRALHLVEDLRGLLEMMEADEREGLRCQVPDSTAEALIEWLQSQMTNGHISGNGDVYQERLARLENDKESLVLQVSVLTDQVEAQGEKIRDLEFCLEEHREKLNATEEMLQQELLSRTSLETQKLDLMAEISNLKLKLTSVEKDRLDYEDRFRDTEDLIQEINELRLRVGEMDNERLQYEKKLKTTKSLMAKLSSMKIKVGQMQYEKQRMEQKCQMLKDELSALKEKLEQKEAEVKRLQEKLVCKLKGEGIEILDRDENCKKKLKDKNIEVQKMKKAVESLMAANEEKDRKIEELRQSLNRYKKVQDMVILAQGKKGKDSDSEDFLNSGSISTVLLDTPSLTDPEKSPSLTPVTASPIHDEFNTNIHDENSLQIHKSILQISIPSFSSASMSSETAAEKVKTQPRPDPTSDLSEVRSTRSSPETQLCDSPVTSSLQKSSSLSSLKKETSETDRDSASQKPTEVKPRTEGNNFATLPPKSPSHGITGDEDSFGTRKARSSFGRGFFKIKNNKRTASAPNLDRSRSASAPTLAETEKGSADHLDLAGLPPRPKETDSLQMTPPSPDSRKKARGIKKLFGRLKRSQSTTFNPDDMSEMEFKRGGTRATAGPRLGWSRDLGQSRNELDMPFAKWTKEQVCNWLQDQGLGSYISNGRHWILSGQTLLQASQQDLEKELGIKHPLHRKKLQLALQALGSEEENNHGKLDYHWVTRWLDDIGLPQYKTQFDEGKVDGRMLHYMTVDDLLSLKVVSVLHHLSIKRAIQVLRINNFEPNCLRRRPSDENNVTPSEVTQWTNHRVMEWLRSVDLAEYAPNLRGSGVHGGLMVLEPRFNVETMAQLLNIPPNKTLLRRHLATHFNLLIGQEAQQQKREAMESPDYVLLTATAKVKPKKLAFSNFGSLRKKKQDDVEEYVCPMELGRASGSASKKGFKAGLDIRVYDDDDLDRLEQMEDSEGTVRQIGAFSEGINNLTHMLKEDEMFKDFATRSPSTSITDEDSNV", "length": 1039, "header": "tr|A0A8V0YIL8-1|A0A8V0YIL8_CHICK Isoform 1 of PPFIA binding protein 1 OS=Gallus gallus OX=9031 GN=PPFIBP1 PE=1 SV=1 CANONICAL=A0A8V0YIL8-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YC68-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIL8/entry#A0A8V0YC68-1", "sequence": { "sequence": "MKIAASSMEYSWDIHGHCVWLNKTNGHISGNGDVYQERLARLENDKESLVLQVSVLTDQVEAQGEKIRDLEFCLEEHREKLNATEEMLQQELLSRTSLETQKLDLMAEISNLKLKLTSVEKDRLDYEDRFRDTEDELSALKEKLEQKEAEVKRLQEKLVCKLKGEGIEILDRDIEVQKMKKAVESLMAANEEKDRKIEELRQSLNRYKKVQDMVILAQGKKGKDSDSEDFLNSGSISTVLLDTPSLTDPEKSPSLTPVTASPIHDEFNTNIHDENSLQIHKSILQISIPSFSSASMSSETAAEKVKTQPRPDPTSDLSEVRSTRSSPETQLCDSPVTSSLQKSSSLSSLKKETSETDRDSASQKPTEVKPRTEGNNFATLPPKSPSHGITGDEDSFGTRKARSSFGRGFFKIKNNKRTASAPNLAETEKGSADHLDLAGLPPRPKETDSLQMTPPSPDSRKKARGIKKLFGRLKRSQSTTFNPDDMSEMEFKRGGTRATAGPRLGWSRDLGQSRNELDMPFAKWTKEQVCNWLQDQGLGSYISNGRHWILSGQTLLQASQQDLEKELGIKHPLHRKKLQLALQALGSEEENNHGKLDYHWVTRWLDDIGLPQYKTQFDEGKVDGRMLHYMTVDDLLSLKVVSVLHHLSIKRAIQVLRINNFEPNCLRRRPSDENNVTPSEVTQWTNHRVMEWLRSVDLAEYAPNLRGSGVHGGLMVLEPRFNVETMAQLLNIPPNKTLLRRHLATHFNLLIGQEAQQQKREAMESPDYVLLTATAKVKPKKLAFSNFGSLRKKKQDDVEEYVCPMELGRASGSASKKGFKAGLDIRVYDDDDLDRLEQMEDSEGTVRQIGAFSEGINNLTHMLKEDEMFKDFATRSPSTSITDEDSNV", "length": 888, "header": "tr|A0A8V0YC68-1|A0A8V0YC68_CHICK Computationally mapped isoform of PPFIA binding protein 1 OS=Gallus gallus OX=9031 GN=PPFIBP1 PE=1 SV=1 CANONICAL=A0A8V0YIL8-1" }, "locus": { "chromosome": "1", "start_pos": 68372219, "end_pos": 68334421, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031473.1", "url": "https://www.ensembl.org/id/ENSGALT00010031473.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018377.1", "url": "https://www.ensembl.org/id/ENSGALP00010018377.1" } ] } }, { "isoform_ac": "A0A8V0YC71-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIL8/entry#A0A8V0YC71-1", "sequence": { "sequence": "MKIAASSMEYSWDIHGHCVWLNKTNGHISGNGDVYQERLARLENDKESLVLQVSVLTDQVEAQGEKIRDLEFCLEEHREKLNATEEMLQQELLSRTSLETQKLDLMAEISNLKLKLTSVEKDRLDYEDRFRDTEDLIQEINELRLRVGEMDNERLQYEKKLKTTKSLMAKLSSMKIKVGQMQYEKQRMEQKCQMLKDELSALKEKLEQKEAEVKRLQEKLVCKLKGEGIEILDRDENCKKKLKDKNIEVQKMKKAVESLMAANEEKDRKIEELRQSLNRYKKVQDMVILAQGKKGKDSDSEDFLNSGSISTVLLDTPSLTDPEKSPSLTPVTASPIHDEFNTNIHDENSLQIHKSILQISIPSFSSASMSSETAAEKVKTQPRPDPTSDLSEVRSTRSSPETQLCDSPVTSSLQKSSSLSSLKKETSETDRDSASQKPTEVKPRTEGNNFATLPPKSPSHGITGDEDSFGTRKARSSFGRGFFKIKNNKRTASAPNLDRSRSASAPTLAETEKGSADHLDLAGLPPRPKETDSLQMTPPSPDSRKKARGIKKLFGRLKRSQSTTFNPDDMSEMEFKRGGTRATAGPRLGWSRDLGQSRNELDMPFAKWTKEQVCNWLQDQGLGSYISNGRHWILSGQTLLQASQQDLEKELGIKHPLHRKKLQLALQALGSEEENNHGKLDYHWVTRWLDDIGLPQYKTQFDEGKVDGRMLHYMTVDDLLSLKVVSVLHHLSIKRAIQVLRINNFEPNCLRRRPSDENNVTPSEVTQWTNHRVMEWLRSVDLAEYAPNLRGSGVHGGLMVLEPRFNVETMAQLLNIPPNKTLLRRHLATHFNLLIGQEAQQQKREAMESPDYVLLTATAKVKPKKLAFSNFGSLRKKKQDDVEEYVCPMELGRASGSASKKGFKAGLDIRVYDDDDLDRLEQMEDSEGTVRQIGAFSEGINNLTHMLKEDEMFKDFATRSPSTSITDEDSNV", "length": 972, "header": "tr|A0A8V0YC71-1|A0A8V0YC71_CHICK Computationally mapped isoform of PPFIA binding protein 1 OS=Gallus gallus OX=9031 GN=PPFIBP1 PE=1 SV=1 CANONICAL=A0A8V0YIL8-1" }, "locus": { "chromosome": "1", "start_pos": 68372219, "end_pos": 68334421, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031482.1", "url": "https://www.ensembl.org/id/ENSGALT00010031482.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018382.1", "url": "https://www.ensembl.org/id/ENSGALP00010018382.1" } ] } }, { "isoform_ac": "A0A8V0YC80-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIL8/entry#A0A8V0YC80-1", "sequence": { "sequence": "MMSDASDMLAAALEQMDGIIAGSKALEYSNGIFDCQSPTSPFMGGLRALHLVEDLRGLLEMMEADEREGLRCQVPDSTAEALIEWLQSQMTNGHISGNGDVYQERLARLENDKESLVLQVSVLTDQVEAQGEKIRDLEFCLEEHREKLNATEEMLQQELLSRTSLETQKLDLMAEISNLKLKLTSVEKDRLDYEDRFRDTEDLIQEINELRLRVGEMDNERLQYEKKLKTTKSLMAKLSSMKIKVGQMQYEKQRMEQKCQMLKDELSALKEKLEQKEAEVKRLQEKLVCKLKGEGIEILDRDENCKKKLKDKNIEVQKMKKAVESLMAANEEKDRKIEELRQSLNRYKKVQDMVILAQGKKGKDSDSEDFLNSGSISTVLLDTPSLTDPEKSPSLTPVTASPIHDEFNTNIHDENSLQIHKSILQISIPSFSSASMSSETAAEKVKTQPRPDPTSDLSEVRSTRSSPETQLCDSPVTSSLQKSSSLSSLKKETSETDRDSASQKPTEQVKPRTEGNNFATLPPKSPSHGITGDEDSFGTRKARSSFGRGFFKIKNNKRTASAPNLAETEKGSADHLDLAGLPPRPKETDSLQMTPPSPDSRKKARGIKKLFGRLKRSQSTTFNPDDMSEMEFKRGGTRATAGPRLGWSRDLGQSRNELDMPFAKWTKEQVCNWLQDQGLGSYISNGRHWILSGQTLLQASQQDLEKELGIKHPLHRKKLQLALQALGSEEENNHGKLDYHWVTRWLDDIGLPQYKTQFDEGKVDGRMLHYMTVDDLLSLKVVSVLHHLSIKRAIQVLRINNFEPNCLRRRPSDENNVTPSEVTQWTNHRVMEWLRSVDLAEYAPNLRGSGVHGGLMVLEPRFNVETMAQLLNIPPNKTLLRRHLATHFNLLIGQEAQQQKREAMESPDYVLLTATAKVKPKKLAFSNFGSLRKKKQDDVEEYVCPMELGRASGSASKKGFKAGLDIRVYDDDDLDRLEQMEDSEGTVRQIGAFSEGINNLTHMLKEDEMFKDFATRSPSTSITDEDSNV", "length": 1029, "header": "tr|A0A8V0YC80-1|A0A8V0YC80_CHICK Computationally mapped isoform of PPFIA binding protein 1 OS=Gallus gallus OX=9031 GN=PPFIBP1 PE=1 SV=1 CANONICAL=A0A8V0YIL8-1" }, "locus": { "chromosome": "1", "start_pos": 68372219, "end_pos": 68326258, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031505.1", "url": "https://www.ensembl.org/id/ENSGALT00010031505.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018400.1", "url": "https://www.ensembl.org/id/ENSGALP00010018400.1" } ] } }, { "isoform_ac": "A0A8V0YHN0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIL8/entry#A0A8V0YHN0-1", "sequence": { "sequence": "MKIAASSMEYSWDIHGHCVWLNKTNGHISGNGDVYQERLARLENDKESLVLQVSVLTDQVEAQGEKIRDLEFCLEEHREKLNATEEMLQQELLSRTSLETQKLDLMAEISNLKLKLTSVEKDRLDYEDRFRDTEDLIQEINELRLRVGEMDNERLQYEKKLKTTKDELSALKEKLEQKEAEVKRLQEKLVCKLKGEGIEILDRDIEVQKMKKAVESLMAANEEKDRKIEELRQSLNRYKKVQDMVILAQGKKGKDSDSEDFLNSGSISTVLLDTPSLTDPEKSPSLTPVTASPIHDEFNTNIHDENSLQIHKSILQISIPSFSSASMSSETAAEKVKTQPRPDPTSDLSEVRSTRSSPETQLCDSPVTSSLQKSSSLSSLKKETSETDRDSASQKPTEVKPRTEGNNFATLPPKSPSHGITGDEDSFGTRKARSSFGRGFFKIKNNKRTASAPNLAETEKGSADHLDLAGLPPRPKETDSLQMTPPSPDSRKKARGIKKLFGRLKRSQSTTFNPDDMSEMEFKRGGTRATAGPRLGWSRDLGQSRNELDMPFAKWTKEQVCNWLQDQGLGSYISNGRHWILSGQTLLQASQQDLEKELGIKHPLHRKKLQLALQALGSEEENNHGKLDYHWVTRWLDDIGLPQYKTQFDEGKVDGRMLHYMTVDDLLSLKVVSVLHHLSIKRAIQVLRINNFEPNCLRRRPSDENNVTPSEVTQWTNHRVMEWLRSVDLAEYAPNLRGSGVHGGLMVLEPRFNVETMAQLLNIPPNKTLLRRHLATHFNLLIGQEAQQQKREAMESPDYVLLTATAKVKPKKLAFSNFGSLRKKKQDDVEEYVCPMELGRASGSASKKGFKAGLDIRVYDDDDLDRLEQMEDSEGTVRQIGAFSEGINNLTHMLKEDEMFKDFATRSPSTSITDEDSNV", "length": 919, "header": "tr|A0A8V0YHN0-1|A0A8V0YIL8_CHICK Computationally mapped isoform of PPFIA binding protein 1 OS=Gallus gallus OX=9031 GN=PPFIBP1 PE=1 SV=1 CANONICAL=A0A8V0YIL8-1" }, "locus": { "chromosome": "1", "start_pos": 68372219, "end_pos": 68334421, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031466.1", "url": "https://www.ensembl.org/id/ENSGALT00010031466.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018371.1", "url": "https://www.ensembl.org/id/ENSGALP00010018371.1" } ] } }, { "isoform_ac": "A0A8V0YHP7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIL8/entry#A0A8V0YHP7-1", "sequence": { "sequence": "MMSDASDMLAAALEQMDGIIAGSKALEYSNGIFDCQSPTSPFMGGLRALHLVEDLRGLLEMMEADEREGLRCQVPDSTAEALIEWLQSQMTNGHISGNGDVYQERLARLENDKESLVLQVSVLTDQVEAQGEKIRDLEFCLEEHREKLNATEEMLQQELLSRTSLETQKLDLMAEISNLKLKLTSVEKDRLDYEDRFRDTEDLIQEINELRLRVGEMDNERLQYEKKLKTTKSLMAKLSSMKIKVGQMQYEKQRMEQKCQMLKDELSALKEKLEQKEAEVKRLQEKLVCKLKGEGIEILDRDIEVQKMKKAVESLMAANEEKDRKIEELRQSLNRYKKVQDMVILAQGKKGKDSDSEDFLNSGSISTVLLDTPSLTDPEKSPSLTPVTASPIHDEFNTNIHDENSLQIHKSILQISIPSFSSASMSSETAAEKVKTQPRPDPTSDLSEVRSTRSSPETQLCDSPVTSSLQKSSSLSSLKKETSETDRDSASQKPTEVKPRTEGNNFATLPPKSPSHGITGDEDSFGTRKARSSFGRGFFKIKNNKRTASAPNLAETEKGSADHLDLAGLPPRPKETDSLQMTPPSPDSRKKARGIKKLFGRLKRSQSTTFNPDDMSEMEFKRGGTRATAGPRLGWSRDLGQSRNELDMPFAKWTKEQVCNWLQDQGLGSYISNGRHWILSGQTLLQASQQDLEKELGIKHPLHRKKLQLALQALGSEEENNHGKLDYHWVTRWLDDIGLPQYKTQFDEGKVDGRMLHYMTVDDLLSLKVVSVLHHLSIKRAIQVLRINNFEPNCLRRRPSDENNVTPSEVTQWTNHRVMEWLRSVDLAEYAPNLRGSGVHGGLMVLEPRFNVETMAQLLNIPPNKTLLRRHLATHFNLLIGQEAQQQKREAMESPDYVLLTATAKVKPKKLAFSNFGSLRKKKQDDVEEYVCPMELGRASGSASKKGFKAGLDIRVYDDDDLDRLEQMEDSEGTVRQIGAFSEGINNLTHMLKEDEMFKDFATRSPSTSITDEDSNV", "length": 1017, "header": "tr|A0A8V0YHP7-1|A0A8V0YIL8_CHICK Computationally mapped isoform of PPFIA binding protein 1 OS=Gallus gallus OX=9031 GN=PPFIBP1 PE=1 SV=1 CANONICAL=A0A8V0YIL8-1" }, "locus": { "chromosome": "1", "start_pos": 68372219, "end_pos": 68326258, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031489.1", "url": "https://www.ensembl.org/id/ENSGALT00010031489.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018389.1", "url": "https://www.ensembl.org/id/ENSGALP00010018389.1" } ] } }, { "isoform_ac": "A0A8V0YIJ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIL8/entry#A0A8V0YIJ8-1", "sequence": { "sequence": "MKIAASSMEYSWDIHGHCVWLNKTNGHISGNGDVYQERLARLENDKESLVLQVSVLTDQVEAQGEKIRDLEFCLEEHREKLNATEEMLQQELLSRTSLETQKLDLMAEISNLKLKLTSVEKDRLDYEDRFRDTEDLIQEINELRLRVGEMDNERLQYEKKLKTTKDELSALKEKLEQKEAEVKRLQEKLVCKLKGEGIEILDRDIEVQKMKKAVESLMAANEEKDRKIEELRQSLNRYKKVQDMVILAQGKKGKDSDSEDFLNSGSISTVLLDTPSLTDPEKSPSLTPVTASPIHDEFNTNIHDENSLQIHKSILQISIPSFSSASMSSETAAEKVKTQPRPDPTSDLSEVRSTRSSPETQLCDSPVTSSLQKSSSLSSLKKETSETVGQVKPRTEGNNFATLPPKSPSHGITGDEDSFGTRKARSSFGRGFFKIKNNKRTASAPNLAETEKGSADHLDLAGLPPRPKETDSLQMTPPSPDSRKKARGIKKLFGRLKRSQSTTFNPDDMSEMEFKRGGTRATAGPRLGWSRDLGQSRNELDMPFAKWTKEQVCNWLQDQGLGSYISNGRHWILSGQTLLQASQQDLEKELGIKHPLHRKKLQLALQALGSEEENNHGKLDYHWVTRWLDDIGLPQYKTQFDEGKVDGRMLHYMTVDDLLSLKVVSVLHHLSIKRAIQVLRINNFEPNCLRRRPSDENNVTPSEVTQWTNHRVMEWLRSVDLAEYAPNLRGSGVHGGLMVLEPRFNVETMAQLLNIPPNKTLLRRHLATHFNLLIGQEAQQQKREAMESPDYVLLTATAKVKPKKLAFSNFGSLRKKKQDDVEEYVCPMELGRASGSASKKGFKAGLDIRVYDDDDLDRLEQMEDSEGTVRQIGAFSEGINNLTHMLKEDEMFKDFATRSPSTSITDEDSNV", "length": 911, "header": "tr|A0A8V0YIJ8-1|A0A8V0YIJ8_CHICK Computationally mapped isoform of PPFIA binding protein 1 OS=Gallus gallus OX=9031 GN=PPFIBP1 PE=1 SV=1 CANONICAL=A0A8V0YIL8-1" }, "locus": { "chromosome": "1", "start_pos": 68372219, "end_pos": 68334421, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031470.1", "url": "https://www.ensembl.org/id/ENSGALT00010031470.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018374.1", "url": "https://www.ensembl.org/id/ENSGALP00010018374.1" } ] } }, { "isoform_ac": "A0A8V0YIL8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIL8/entry#A0A8V0YIL8-1", "sequence": { "sequence": "MMSDASDMLAAALEQMDGIIAGSKALEYSNGIFDCQSPTSPFMGGLRALHLVEDLRGLLEMMEADEREGLRCQVPDSTAEALIEWLQSQMTNGHISGNGDVYQERLARLENDKESLVLQVSVLTDQVEAQGEKIRDLEFCLEEHREKLNATEEMLQQELLSRTSLETQKLDLMAEISNLKLKLTSVEKDRLDYEDRFRDTEDLIQEINELRLRVGEMDNERLQYEKKLKTTKSLMAKLSSMKIKVGQMQYEKQRMEQKCQMLKDELSALKEKLEQKEAEVKRLQEKLVCKLKGEGIEILDRDENCKKKLKDKNIEVQKMKKAVESLMAANEEKDRKIEELRQSLNRYKKVQDMVILAQGKKGKDSDSEDFLNSGSISTVLLDTPSLTDPEKSPSLTPVTASPIHDEFNTNIHDENSLQIHKSILQISIPSFSSASMSSETAAEKVKTQPRPDPTSDLSEVRSTRSSPETQLCDSPVTSSLQKSSSLSSLKKETSETDRDSASQKPTEVKPRTEGNNFATLPPKSPSHGITGDEDSFGTRKARSSFGRGFFKIKNNKRTASAPNLDRSRSASAPTLAETEKGSADHLDLAGLPPRPKETDSLQMTPPSPDSRKKARGIKKLFGRLKRSQSTTFNPDDMSEMEFKRGGTRATAGPRLGWSRDLGQSRNELDMPFAKWTKEQVCNWLQDQGLGSYISNGRHWILSGQTLLQASQQDLEKELGIKHPLHRKKLQLALQALGSEEENNHGKLDYHWVTRWLDDIGLPQYKTQFDEGKVDGRMLHYMTVDDLLSLKVVSVLHHLSIKRAIQVLRINNFEPNCLRRRPSDENNVTPSEVTQWTNHRVMEWLRSVDLAEYAPNLRGSGVHGGLMVLEPRFNVETMAQLLNIPPNKTLLRRHLATHFNLLIGQEAQQQKREAMESPDYVLLTATAKVKPKKLAFSNFGSLRKKKQDDVEEYVCPMELGRASGSASKKGFKAGLDIRVYDDDDLDRLEQMEDSEGTVRQIGAFSEGINNLTHMLKEDEMFKDFATRSPSTSITDEDSNV", "length": 1039, "header": "tr|A0A8V0YIL8-1|A0A8V0YIL8_CHICK Isoform 1 of PPFIA binding protein 1 OS=Gallus gallus OX=9031 GN=PPFIBP1 PE=1 SV=1 CANONICAL=A0A8V0YIL8-1" }, "locus": { "chromosome": "1", "start_pos": 68372219, "end_pos": 68326258, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031507.1", "url": "https://www.ensembl.org/id/ENSGALT00010031507.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018402.1", "url": "https://www.ensembl.org/id/ENSGALP00010018402.1" } ] } }, { "isoform_ac": "A0A8V0YQD2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIL8/entry#A0A8V0YQD2-1", "sequence": { "sequence": "MKIAASSMEYSWDIHGHCVWLNKTNGHISGNGDVYQERLARLENDKESLVLQVSVLTDQVEAQGEKIRDLEFCLEEHREKLNATEEMLQQELLSRTSLETQKLDLMAEISNLKLKLTSVEKDRLDYEDRFRDTEDLIQEINELRLRVGEMDNERLQYEKKLKTTKDELSALKEKLEQKEAEVKRLQEKLVCKLKGEGIEILDRDENCKKKLKDKNIEVQKMKKAVESLMAANEEKDRKIEELRQSLNRYKKVQDMVILAQGKKGKDSDSEDFLNSGSISTVLLDTPSLTDPEKSPSLTPVTASPIHDEFNTNIHDENSLQIHKSILQISIPSFSSASMSSETAAEKVKTQPRPDPTSDLSEVRSTRSSPETQLCDSPVTSSLQKSSSLSSLKKETSETDRDSASQKPTEVKPRTEGNNFATLPPKSPSHGITGDEDSFGTRKARSSFGRGFFKIKNNKRTASAPNLAETEKGSADHLDLAGLPPRPKETDSLQMTPPSPDSRKKARGIKKLFGRLKRSQSTTFNPDDMSEMEFKRGGTRATAGPRLGWSRDLGQSRNELDMPFAKWTKEQVCNWLQDQGLGSYISNGRHWILSGQTLLQASQQDLEKELGIKHPLHRKKLQLALQALGSEEENNHGKLDYHWVTRWLDDIGLPQYKTQFDEGKVDGRMLHYMTVDDLLSLKVVSVLHHLSIKRAIQVLRINNFEPNCLRRRPSDENNVTPSEVTQWTNHRVMEWLRSVDLAEYAPNLRGSGVHGGLMVLEPRFNVETMAQLLNIPPNKTLLRRHLATHFNLLIGQEAQQQKREAMESPDYVLLTATAKVKPKKLAFSNFGSLRKKKQDDVEEYVCPMELGRASGSASKKGFKAGLDIRVYDDDDLDRLEQMEDSEGTVRQIGAFSEGINNLTHMLKEDEMFKDFATRSPSTSITDEDSNV", "length": 930, "header": "tr|A0A8V0YQD2-1|A0A8V0YQD2_CHICK Computationally mapped isoform of PPFIA binding protein 1 OS=Gallus gallus OX=9031 GN=PPFIBP1 PE=1 SV=1 CANONICAL=A0A8V0YIL8-1" }, "locus": { "chromosome": "1", "start_pos": 68372219, "end_pos": 68334421, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031462.1", "url": "https://www.ensembl.org/id/ENSGALT00010031462.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018368.1", "url": "https://www.ensembl.org/id/ENSGALP00010018368.1" } ] } }, { "isoform_ac": "A0A8V0YQG1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIL8/entry#A0A8V0YQG1-1", "sequence": { "sequence": "MMSDASDMLAAALEQMDGIIAGSKALEYSNGIFDCQSPTSPFMGGLRALHLVEDLRGLLEMMEADEREGLRCQVPDSTAEALIEWLQSQMTNGHISGNGDVYQERLARLENDKESLVLQVSVLTDQVEAQGEKIRDLEFCLEEHREKLNATEEMLQQELLSRTSLETQKLDLMAEISNLKLKLTSVEKDRLDYEDRFRDTEDLIQEINELRLRVGEMDNERLQYEKKLKTTKDELSALKEKLEQKEAEVKRLQEKLVCKLKGEGIEILDRDIEVQKMKKAVESLMAANEEKDRKIEELRQSLNRYKKVQDMVILAQGKKGKDSDSEDFLNSGSISTVLLDTPSLTDPEKSPSLTPVTASPIHDEFNTNIHDENSLQIHKSILQISIPSFSSASMSSETAAEKVKTQPRPDPTSDLSEVRSTRSSPETQLCDSPVTSSLQKSSSLSSLKKETSETDRDSASQKPTEQVKPRTEGNNFATLPPKSPSHGITGDEDSFGTRKARSSFGRGFFKIKNNKRTASAPNLAETEKGSADHLDLAGLPPRPKETDSLQMTPPSPDSRKKARGIKKLFGRLKRSQSTTFNPDDMSEMEFKRGGTRATAGPRLGWSRDLGQSRNELDMPFAKWTKEQVCNWLQDQGLGSYISNGRHWILSGQTLLQASQQDLEKELGIKHPLHRKKLQLALQALGSEEENNHGKLDYHWVTRWLDDIGLPQYKTQFDEGKVDGRMLHYMTVDDLLSLKVVSVLHHLSIKRAIQVLRINNFEPNCLRRRPSDENNVTPSEVTQWTNHRVMEWLRSVDLAEYAPNLRGSGVHGGLMVLEPRFNVETMAQLLNIPPNKTLLRRHLATHFNLLIGQEAQQQKREAMESPDYVLLTATAKVKPKKLAFSNFGSLRKKKQDDVEEYVCPMELGRASGSASKKGFKAGLDIRVYDDDDLDRLEQMEDSEGTVRQIGAFSEGINNLTHMLKEDEMFKDFATRSPSTSITDEDSNV", "length": 987, "header": "tr|A0A8V0YQG1-1|A0A8V0YQG1_CHICK Computationally mapped isoform of PPFIA binding protein 1 OS=Gallus gallus OX=9031 GN=PPFIBP1 PE=1 SV=1 CANONICAL=A0A8V0YIL8-1" }, "locus": { "chromosome": "1", "start_pos": 68372219, "end_pos": 68326258, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031514.1", "url": "https://www.ensembl.org/id/ENSGALT00010031514.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018406.1", "url": "https://www.ensembl.org/id/ENSGALP00010018406.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:418219", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418219", "resource": "KEGG Pathway" }, { "id": "R-GGA-388844", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-388844", "resource": "Reactome", "description": "Receptor-type tyrosine-protein phosphatases" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIL8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIL8" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIL8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIL8" } ], "pmid": "" }, { "name": "cell cortex", "id": "GO:0005938", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005938", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIL8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIL8" } ], "pmid": "" }, { "name": "presynaptic active zone", "id": "GO:0048786", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048786", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIL8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIL8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "neuromuscular junction development", "id": "GO:0007528", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007528", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIL8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIL8" } ], "pmid": "" }, { "name": "cortical microtubule organization", "id": "GO:0043622", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043622", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIL8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIL8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1009, "end_pos": 1011, "annotation": "n_glycosylation_sequon" }, { "start_pos": 149, "end_pos": 151, "annotation": "n_glycosylation_sequon" }, { "start_pos": 826, "end_pos": 828, "annotation": "n_glycosylation_sequon" }, { "start_pos": 886, "end_pos": 888, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YIL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIL8" }, { "id": "PS50105", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50105" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SAM", "eco_id": "ECO_0000259", "start_pos": 675, "end_pos": 739, "start_aa": "Trp", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1009, "end_pos": 1011 }, { "start_pos": 149, "end_pos": 151 }, { "start_pos": 826, "end_pos": 828 }, { "start_pos": 886, "end_pos": 888 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YIV0-1", "uniprot_ac": "A0A8V0YIV0", "uniprot_id": "A0A8V0YIV0_CHICK", "mass": { "chemical_mass": 36186.0, "monoisotopic_mass": 36186.0 }, "refseq": {}, "gene_names": [ { "name": "NR0B2", "type": "recommended", "evidence": [ { "id": "A0A8V0YIV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV0" } ] } ], "protein_names": [ { "name": "Nuclear receptor subfamily 0 group B member 2", "type": "synonym", "evidence": [ { "id": "A0A8V0YIV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV0/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIV0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "NR0B2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV0", "locus": { "chromosome": "23", "start_pos": 2182872, "end_pos": 2186912, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013182", "url": "https://www.ensembl.org/id/ENSGALG00010013182" } ] } } ], "crossref": [ { "id": "A0A8V0YIV0", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YIV0", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd07349", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07349", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000536", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000536", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001723", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001723", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033544", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033544", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035500", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035500", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YHZ8", "url": "https://www.orthodb.org/?gene=A0A8V0YHZ8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YIV0", "url": "https://www.orthodb.org/?gene=A0A8V0YIV0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24081", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24081", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24081:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24081:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00104", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00104", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-383280", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-383280", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YHZ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHZ8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHZ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHZ8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YIV0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YIV0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MARRMPSKRSSCSAASSALNPILPATGLLRALTLLLTGTGSKLGGSGKAGIRAPTSALVTSSTDMDCERCQCQHEDKHSAILYTLLSQNLSHSPPHQRCLCHQRWTVCLRTPHITCQAASDVLVKTISFMKNLPSFHLLPRGDQLLLLDSCWVPLFLLGLVQEMVTFEVMETPAPSMLEKILLDGQSKRQEPEWTQPMLAAVQWLQCSLNTFWSLDLSPKEYAYLKGAILFNPDVPGLTASLYIESLQREAERALQEVVQILHPKDQDRFALILLITSTLKSIPPALITDLFFRPIIGNADIVELIVDMLYEITSWQPAPSPRMAL", "length": 326, "header": "tr|A0A8V0YIV0-1|A0A8V0YIV0_CHICK Isoform 1 of Nuclear receptor subfamily 0 group B member 2 OS=Gallus gallus OX=9031 GN=NR0B2 PE=3 SV=1 CANONICAL=A0A8V0YIV0-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YHZ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV0/entry#A0A8V0YHZ8-1", "sequence": { "sequence": "MKSIIVCCHFLSADQNIQIPEQFKGIRAPTSALVTSSTDMDCERCQCQHEDKHSAILYTLLSQNLSHSPPHQRCLCHQRWTVCLRTPHITCQAASDVLVKTISFMKNLPSFHLLPRGDQLLLLDSCWVPLFLLGLVQEMVTFEVMETPAPSMLEKILLDGQSKRQEPEWTQPMLAAVQWLQCSLNTFWSLDLSPKEYAYLKGAILFNPDVPGLTASLYIESLQREAERALQEVVQILHPKDQDRFALILLITSTLKSIPPALITDLFFRPIIGNADIVELIVDMLYEITSWQPAPSPRMAL", "length": 301, "header": "tr|A0A8V0YHZ8-1|A0A8V0YIV0_CHICK Computationally mapped isoform of Nuclear receptor subfamily 0 group B member 2 OS=Gallus gallus OX=9031 GN=NR0B2 PE=3 SV=1 CANONICAL=A0A8V0YIV0-1" }, "locus": { "chromosome": "23", "start_pos": 2186047, "end_pos": 2184005, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031618.1", "url": "https://www.ensembl.org/id/ENSGALT00010031618.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018484.1", "url": "https://www.ensembl.org/id/ENSGALP00010018484.1" } ] } }, { "isoform_ac": "A0A8V0YIV0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV0/entry#A0A8V0YIV0-1", "sequence": { "sequence": "MARRMPSKRSSCSAASSALNPILPATGLLRALTLLLTGTGSKLGGSGKAGIRAPTSALVTSSTDMDCERCQCQHEDKHSAILYTLLSQNLSHSPPHQRCLCHQRWTVCLRTPHITCQAASDVLVKTISFMKNLPSFHLLPRGDQLLLLDSCWVPLFLLGLVQEMVTFEVMETPAPSMLEKILLDGQSKRQEPEWTQPMLAAVQWLQCSLNTFWSLDLSPKEYAYLKGAILFNPDVPGLTASLYIESLQREAERALQEVVQILHPKDQDRFALILLITSTLKSIPPALITDLFFRPIIGNADIVELIVDMLYEITSWQPAPSPRMAL", "length": 326, "header": "tr|A0A8V0YIV0-1|A0A8V0YIV0_CHICK Isoform 1 of Nuclear receptor subfamily 0 group B member 2 OS=Gallus gallus OX=9031 GN=NR0B2 PE=3 SV=1 CANONICAL=A0A8V0YIV0-1" }, "locus": { "chromosome": "23", "start_pos": 2186831, "end_pos": 2184005, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031621.1", "url": "https://www.ensembl.org/id/ENSGALT00010031621.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018487.1", "url": "https://www.ensembl.org/id/ENSGALP00010018487.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-383280", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-383280", "resource": "Reactome", "description": "Nuclear Receptor transcription pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIV0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV0" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIV0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV0" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIV0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV0" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIV0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIV0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV0" } ], "pmid": "" }, { "name": "negative regulation of DNA-templated transcription", "id": "GO:0045892", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045892", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIV0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV0" } ], "pmid": "" }, { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIV0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV0" } ], "pmid": "" }, { "name": "positive regulation of gene expression", "id": "GO:0010628", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010628", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIV0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV0" } ], "pmid": "" }, { "name": "negative regulation of gene expression", "id": "GO:0010629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010629", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIV0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV0" } ], "pmid": "" }, { "name": "circadian regulation of gene expression", "id": "GO:0032922", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032922", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIV0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "protein domain specific binding", "id": "GO:0019904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019904", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIV0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV0" } ], "pmid": "" }, { "name": "protein homodimerization activity", "id": "GO:0042803", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042803", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIV0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV0" } ], "pmid": "" }, { "name": "transcription corepressor activity", "id": "GO:0003714", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003714", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIV0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV0" } ], "pmid": "" }, { "name": "nuclear receptor binding", "id": "GO:0016922", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016922", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIV0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV0" } ], "pmid": "" }, { "name": "transcription regulator inhibitor activity", "id": "GO:0140416", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140416", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIV0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 89, "end_pos": 91, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YIV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV0" }, { "id": "PS51843", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51843" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "NR LBD", "eco_id": "ECO_0000259", "start_pos": 77, "end_pos": 313, "start_aa": "Lys", "end_aa": "Ile", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 89, "end_pos": 91 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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{ "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YJ37-1", "uniprot_ac": "A0A8V0YJ37", "uniprot_id": "A0A8V0YJ37_CHICK", "mass": { "chemical_mass": 33349.0, "monoisotopic_mass": 33349.0 }, "refseq": {}, "gene_names": [ { "name": "CRIP2", "type": "recommended", "evidence": [ { "id": "A0A8V0YJ37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ37" } ] } ], "protein_names": [ { "name": "Cysteine rich protein 2", "type": "synonym", "evidence": [ { "id": "A0A8V0YJ37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ37/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJ37", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ37" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CRIP2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ37", "locus": {} } ], "crossref": [ { "id": "A0A8V0YJ37", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YJ37", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd09476", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09476", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "424374", "url": "https://www.ncbi.nlm.nih.gov/gene/424374", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001781", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001781", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:424374", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424374", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YEKPCAE", "url": "https://omabrowser.org/oma/group/YEKPCAE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YI88", "url": "https://www.orthodb.org/?gene=A0A8V0YI88", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YI95", "url": "https://www.orthodb.org/?gene=A0A8V0YI95", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YIA0", "url": "https://www.orthodb.org/?gene=A0A8V0YIA0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YJ22", "url": "https://www.orthodb.org/?gene=A0A8V0YJ22", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YJ27", "url": "https://www.orthodb.org/?gene=A0A8V0YJ27", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YJ37", "url": "https://www.orthodb.org/?gene=A0A8V0YJ37", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YQX5", "url": "https://www.orthodb.org/?gene=A0A8V0YQX5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46074", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46074", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46074:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46074:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46074:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46074:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00412", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00412", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YI88", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI88", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YI88-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI88-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YI95", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI95", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YI95-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI95-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YIA0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIA0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YIA0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIA0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJ22", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ22", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJ22-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ22-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJ27", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ27", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJ27-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ27-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJ37", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ37", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJ37-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ37-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQX5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQX5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQX5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQX5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASKCPKCDKTVYFAEKVSSLGKDWHKFCLKCERCNKTLTPGGHAEHDGKPFCHKPCYATLFGPKGMCGPCLYPAAAPIPTAPNASQELGCHELSGSQNHSCCVQRGRGASGGGSVPTAGPPFLPSFSFLPFPSFLFLPSFLFLPSFLFLPSFLFLPSFLFLPSFLFLPSFLFLPSFSFLPSFSFLPFPSFLFLPSFSFLPFPSFLFLPSFLPSFLPSFLPSFLPSFLPSFLPSFLPSFLPSFLFLPSFSFLPSFLFLPPSLPPSLPPSLPPFPPSLFIYKLQKANSSSNRRWSCSPVPDTAT", "length": 303, "header": "tr|A0A8V0YJ37-1|A0A8V0YJ37_CHICK Isoform 1 of Cysteine rich protein 2 OS=Gallus gallus OX=9031 GN=CRIP2 PE=1 SV=1 CANONICAL=A0A8V0YJ37-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YI88-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ37/entry#A0A8V0YI88-1", "sequence": { "sequence": "RRSPAEKVSSLGKDWHKFCLKCERCNKTLTPGGHAEHDGKPFCHKPCYATLFGPKGVNIGGAGSYIYEKPQIEGQSAPGPIEHPARVEERKVNAAPPKGPSKASSVTTFTGEPNMCPRCGKRVYFAEKVTSLGKDWHRPCLRCERCSKTLTPGGHAEHDGQPYCHKPCYGILFGPKGVNTGAVGSYIYDKDPEAKNQP", "length": 198, "header": "tr|A0A8V0YI88-1|A0A8V0YJ37_CHICK Computationally mapped isoform of Cysteine rich protein 2 OS=Gallus gallus OX=9031 GN=CRIP2 PE=1 SV=1 CANONICAL=A0A8V0YJ37-1" }, "locus": { "chromosome": "8", "start_pos": 4004369, "end_pos": 4000310, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031712.1", "url": "https://www.ensembl.org/id/ENSGALT00010031712.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018560.1", "url": "https://www.ensembl.org/id/ENSGALP00010018560.1" } ] } }, { "isoform_ac": "A0A8V0YI95-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ37/entry#A0A8V0YI95-1", "sequence": { "sequence": "MQPLPRVLGRPLREHAWALQNVNRGHSAPRGVRCGGRTRPWEAAHCSEKVSSLGKDWHKFCLKCERCNKTLTPGGHAEHDGKPFCHKPCYATLFGPKGVNIGGAGSYIYEKPQIEGQSAPGPIEHPARVEERKVNAAPPKGPSKASSVTTFTGEPNMCPRCGKRVYFAEKVTSLGKDWHRPCLRCERCSKTLTPGGHAEHDGQPYCHKPCYGILFGPKGVNTGAVGSYIYDKDPEAKNQP", "length": 240, "header": "tr|A0A8V0YI95-1|A0A8V0YJ37_CHICK Computationally mapped isoform of Cysteine rich protein 2 OS=Gallus gallus OX=9031 GN=CRIP2 PE=1 SV=1 CANONICAL=A0A8V0YJ37-1" }, "locus": { "chromosome": "8", "start_pos": 4006770, "end_pos": 4000310, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031717.1", "url": "https://www.ensembl.org/id/ENSGALT00010031717.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018565.1", "url": "https://www.ensembl.org/id/ENSGALP00010018565.1" } ] } }, { "isoform_ac": "A0A8V0YIA0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ37/entry#A0A8V0YIA0-1", "sequence": { "sequence": "LLSDGFWKLSFQAQRGTQPPPLGRGSAALAAEKVSSLGKDWHKFCLKCERCNKTLTPGGHAEHDGKPFCHKPCYATLFGPKGVNIGGAGSYIYEKPQIEGQSAPGPIEHPARVEERKVNAAPPKGPSKASSVTTFTGEPNMCPRCGKRVYFAEKVTSLGKDWHRPCLRCERCSKTLTPGGHAEHDGQPYCHKPCYGILFGPKGVNTGAVGSYIYDKDPEAKNQP", "length": 224, "header": "tr|A0A8V0YIA0-1|A0A8V0YJ37_CHICK Computationally mapped isoform of Cysteine rich protein 2 OS=Gallus gallus OX=9031 GN=CRIP2 PE=1 SV=1 CANONICAL=A0A8V0YJ37-1" }, "locus": { "chromosome": "8", "start_pos": 4007353, "end_pos": 4000310, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031722.1", "url": "https://www.ensembl.org/id/ENSGALT00010031722.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018570.1", "url": "https://www.ensembl.org/id/ENSGALP00010018570.1" } ] } }, { "isoform_ac": "A0A8V0YJ22-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ37/entry#A0A8V0YJ22-1", "sequence": { "sequence": "MGWCCFPAVPAADPPAGKEPPGTAVLVLTGPIEKQGWHHVDGDVAEKVSSLGKDWHKFCLKCERCNKTLTPGGHAEHDGKPFCHKPCYATLFGPKGVNIGGAGSYIYEKPQIEGQSAPGPIEHPARVEERKVNAAPPKGPSKASSVTTFTGEPNMCPRCGKRVYFAEKVTSLGKDWHRPCLRCERCSKTLTPGGHAEHDGQPYCHKPCYGILFGPKGVNTGAVGSYIYDKDPEAKNQP", "length": 238, "header": "tr|A0A8V0YJ22-1|A0A8V0YJ22_CHICK Computationally mapped isoform of Cysteine-rich protein 2 OS=Gallus gallus OX=9031 GN=CRIP2 PE=1 SV=1 CANONICAL=A0A8V0YJ37-1" }, "locus": { "chromosome": "8", "start_pos": 4003992, "end_pos": 4000310, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031710.1", "url": "https://www.ensembl.org/id/ENSGALT00010031710.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018558.1", "url": "https://www.ensembl.org/id/ENSGALP00010018558.1" } ] } }, { "isoform_ac": "A0A8V0YJ27-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ37/entry#A0A8V0YJ27-1", "sequence": { "sequence": "RGQGGGWKGQERWSRNAPVRAEKVSSLGKDWHKFCLKCERCNKTLTPGGHAEHDGKPFCHKPCYATLFGPKGVNIGGAGSYIYEKPQIEGQSAPGPIEHPARVEERKVNAAPPKGPSKASSVTTFTGEPNMCPRCGKRVYFAEKVTSLGKDWHRPCLRCERCSKTLTPGGHAEHDGQPYCHKPCYGILFGPKGVNTGAVGSYIYDKDPEAKNQP", "length": 214, "header": "tr|A0A8V0YJ27-1|A0A8V0YJ27_CHICK Computationally mapped isoform of Cysteine-rich protein 2 OS=Gallus gallus OX=9031 GN=CRIP2 PE=1 SV=1 CANONICAL=A0A8V0YJ37-1" }, "locus": { "chromosome": "8", "start_pos": 4006419, "end_pos": 4000310, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031715.1", "url": "https://www.ensembl.org/id/ENSGALT00010031715.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018563.1", "url": "https://www.ensembl.org/id/ENSGALP00010018563.1" } ] } }, { "isoform_ac": "A0A8V0YJ37-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ37/entry#A0A8V0YJ37-1", "sequence": { "sequence": "MASKCPKCDKTVYFAEKVSSLGKDWHKFCLKCERCNKTLTPGGHAEHDGKPFCHKPCYATLFGPKGMCGPCLYPAAAPIPTAPNASQELGCHELSGSQNHSCCVQRGRGASGGGSVPTAGPPFLPSFSFLPFPSFLFLPSFLFLPSFLFLPSFLFLPSFLFLPSFLFLPSFLFLPSFSFLPSFSFLPFPSFLFLPSFSFLPFPSFLFLPSFLPSFLPSFLPSFLPSFLPSFLPSFLPSFLPSFLFLPSFSFLPSFLFLPPSLPPSLPPSLPPFPPSLFIYKLQKANSSSNRRWSCSPVPDTAT", "length": 303, "header": "tr|A0A8V0YJ37-1|A0A8V0YJ37_CHICK Isoform 1 of Cysteine rich protein 2 OS=Gallus gallus OX=9031 GN=CRIP2 PE=1 SV=1 CANONICAL=A0A8V0YJ37-1" }, "locus": { "chromosome": "8", "start_pos": 4008904, "end_pos": 4001342, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031726.1", "url": "https://www.ensembl.org/id/ENSGALT00010031726.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018573.1", "url": "https://www.ensembl.org/id/ENSGALP00010018573.1" } ] } }, { "isoform_ac": "A0A8V0YQX5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ37/entry#A0A8V0YQX5-1", "sequence": { "sequence": "LISNRCPRLGAAHPAEKVSSLGKDWHKFCLKCERCNKTLTPGGHAEHDGKPFCHKPCYATLFGPKGVNIGGAGSYIYEKPQIEGQSAPGPIEHPARVEERKVNAAPPKGPSKASSVTTFTGEPNMCPRCGKRVYFAEKVTSLGKDWHRPCLRCERCSKTLTPGGHAEHDGQPYCHKPCYGILFGPKGVNTGAVGSYIYDKDPEAKNQP", "length": 208, "header": "tr|A0A8V0YQX5-1|A0A8V0YQX5_CHICK Computationally mapped isoform of Cysteine-rich protein 2 OS=Gallus gallus OX=9031 GN=CRIP2 PE=1 SV=1 CANONICAL=A0A8V0YJ37-1" }, "locus": { "chromosome": "8", "start_pos": 4006892, "end_pos": 4000310, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031719.1", "url": "https://www.ensembl.org/id/ENSGALT00010031719.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018567.1", "url": "https://www.ensembl.org/id/ENSGALP00010018567.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:424374", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424374", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "P36201-1", "protein_name": "Cysteine-rich protein 2", "gene_name": "Crip2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASKCPKCDKTVYFAEKVSSLGKDWHKFCLKCERCNKTLTPGGHAEHDGKPFCHKPCYATLFGPKGVNIGGAGSYIYEKPPTEAPQVTGPIEVPVVRTEERKTSGPPKGPSKASSVTTFTGEPNMCPRCNKRVYFAEKVTSLGKDWHRPCLRCERCSKTLTPGGHAEHDGQPYCHKPCYGILFGPKGVNTGAVGSYIYDKDPEGTVQP", "length": 208 }, "evidence": [ { "id": "A0A8V0YJ37", "url": "https://omabrowser.org/oma/group/A0A8V0YJ37/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P52943-1", "protein_name": "Cysteine-rich protein 2", "gene_name": "CRIP2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MASKCPKCDKTVYFAEKVSSLGKDWHKFCLKCERCSKTLTPGGHAEHDGKPFCHKPCYATLFGPKGVNIGGAGSYIYEKPLAEGPQVTGPIEVPAARAEERKASGPPKGPSRASSVTTFTGEPNTCPRCSKKVYFAEKVTSLGKDWHRPCLRCERCGKTLTPGGHAEHDGQPYCHKPCYGILFGPKGVNTGAVGSYIYDRDPEGKVQP", "length": 208 }, "evidence": [ { "id": "A0A8V0YJ37", "url": "https://omabrowser.org/oma/group/A0A8V0YJ37/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9DCT8-1", "protein_name": "Cysteine-rich protein 2", "gene_name": "Crip2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASKCPKCDKTVYFAEKVSSLGKDWHKFCLKCERCNKTLTPGGHAEHDGKPFCHKPCYATLFGPKGVNIGGAGSYIYEKPQTEAPQVTGPIEVPVVRTEERKTSGPPKGPSKASSVTTFTGEPNMCPRCNKRVYFAEKVTSLGKDWHRPCLRCERCSKTLTPGGHAEHDGQPYCHKPCYGILFGPKGVNTGAVGSYIYDKDPEGTVQP", "length": 208 }, "evidence": [ { "id": "A0A8V0YJ37", "url": "https://omabrowser.org/oma/group/A0A8V0YJ37/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJ37", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ37" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJ37", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ37" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "intrinsic apoptotic signaling pathway in response to DNA damage", "id": "GO:0008630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008630", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJ37", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ37" } ], "pmid": "" }, { "name": "regulation of gene expression", "id": "GO:0010468", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010468", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJ37", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ37" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 286, "end_pos": 288, "annotation": "n_glycosylation_sequon" }, { "start_pos": 36, "end_pos": 38, "annotation": "n_glycosylation_sequon" }, { "start_pos": 84, "end_pos": 86, "annotation": "n_glycosylation_sequon" }, { "start_pos": 99, "end_pos": 101, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YJ37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ37" }, { "id": "PS50023", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50023" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "LIM zinc-binding", "eco_id": "ECO_0000259", "start_pos": 3, "end_pos": 64, "start_aa": "Ser", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 286, "end_pos": 288 }, { "start_pos": 36, "end_pos": 38 }, { "start_pos": 84, "end_pos": 86 }, { "start_pos": 99, "end_pos": 101 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YIJ2-1", "uniprot_ac": "A0A8V0YIJ2", "uniprot_id": "A0A8V0YIJ2_CHICK", "mass": { "chemical_mass": 194486.0, "monoisotopic_mass": 194486.0 }, "refseq": { "ac": "XP_015149114", "name": "arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015149114" }, "gene_names": [ { "name": "ARAP3", "type": "recommended", "evidence": [ { "id": "A0A8V0YIJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIJ2" } ] }, { "name": "ARAP3", "type": "synonym", "evidence": [ { "id": "XP_015149114", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015149114" } ] } ], "protein_names": [ { "name": "ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3", "type": "synonym", "evidence": [ { "id": "A0A8V0YIJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIJ2/entry#names_and_taxonomy" } ] }, { "name": "arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015149114", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015149114" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052544.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015149114.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015149114", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015149114" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIJ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIJ2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ARAP3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIJ2", "locus": { "chromosome": "13", "start_pos": 1579575, "end_pos": 1597325, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010011564", "url": "https://www.ensembl.org/id/ENSGALG00010011564" } ] } } ], "crossref": [ { "id": "cd04385", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04385", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd13253", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13253", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd13259", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13259", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd17228", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd17228", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd17902", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd17902", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "416196", "url": "https://www.ncbi.nlm.nih.gov/gene/416196", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000159", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000159", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000198", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000198", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001164", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001164", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001660", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001660", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001849", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001849", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008936", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008936", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013761", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013761", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029071", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029071", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037278", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037278", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037858", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037858", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038508", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038508", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052227", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052227", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:416196", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416196", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "TLNTMEM", "url": "https://omabrowser.org/oma/group/TLNTMEM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YBL6", "url": "https://www.orthodb.org/?gene=A0A8V0YBL6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YIJ2", "url": "https://www.orthodb.org/?gene=A0A8V0YIJ2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45899", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45899", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45899:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45899:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00169", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00169", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00620", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00620", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00788", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00788", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01412", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01412", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07647", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07647", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-8980692", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8980692", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9013148", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013148", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9013149", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013149", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9013423", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013423", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_015149114", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015149114", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YBL6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBL6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YBL6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBL6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YIJ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIJ2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YIJ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIJ2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSSPCTPDSDIADWLATIHLERYRDLFKQHGFHLARDVAALDNKQLQQLGITATGHRKRILNLAEKTRLLGDPHPRAPQMGEDATKAEPGVAADAFGMQKCNAVPRQVMLLQKDLDPPLVRPVPKPRTVFYRPKLEQGSAATPAAHSQDRDGTAGAFVVLEGFVPGESSTDLESPGATMGTGTSRLGAQEEAQLPAVPDHGETQETPEKPCLCVPSVPPRLRHRVPVAELSAVGATVRPPSVPGVGQGRMEMVSNVIYEGFKQPLAPVEDSGQEDSPRGQALTQDPSPQELTQLAEKPNRASWPGGGLPPIPQRPASKPEFSEPPISPYSETTFGNTVPAREQKGTDVPSGQSYEAVTELEQETQRTSSEYSSEGRSEDEETRTRLIERIVQNDTEGYSTVDAPRAKGTPFSLPPHLYPDEVLDDLTISPYASYTSLSEPRPAMLSGWLDKLSPQGNYVFQRRYVRFDGKNLMYFSSEKEPYPKGVIPLPVIEMVRSTKDNKFQVVTSHRIFVFRAENEAQRNEWCSTLQQKVMDQHLVGTRPRPLNTAHCQKSGTLELKGQKSKVFAVLSLPEMWLYKSEQFFKMGIGICMIEMRGSTIREAKNRTFELITPSKIFSFVAESEREKREWMEALQEAIAETLYDYEVAEKIWSNKANRYCADCWAHSPDWASINLCVVICKQCAGQHRSLGSNISKVQSLKLDTSVWSNEIVQLFIVLGNDRANRFWAARIPATEVLHPDASTEQRRDFISRKYRDGRYRLPHPHYASHEDVLQALCTAVAGPSLLKTILQFFSAAEAGLAADPTAPDITPVAEPWWDLESKRNHAGVPGPEGVYNEITQPVAHSGYLHRSMAHPRLPGAKKSRDDFQRVWCSLERALLIFETEKCTEPLSHIQSGDLLSLGVSRAQPISSPGPTERFHFILELFLTGEKVQQLGADSADTLQAWASAIGKWFTPVSCHCLLGYEFQRVGQLRYKCMLNPERWQRAFFILQKAHLFICPAEEDGAEDSINLRRLQELSLVPPAEMPEKKEMLVLVEMGRTFYLQGLSRADTAAWYADIQASAGGRGNALRDQQLSRGDIPIIVDSCIAFITQYGLRHEGIYRKNGAKSRIKVLMEEFRRDARNVKLRISDNFIEDVTDVLKRFFRELEDPVFTLELHPQWKEAAAISSKPQRLERYKELIHRLPRLNRKTLAALIGHLYRVQKCADLNQMSTKNLSLLFAPSLFQTDGKGEHEVKVMEDLIDNYVTIFNIDEDQVSQMDLENSLITTWKDTQLSQAGDLIIEVYLEQKLPDCCVTLKVSPTMTAEELTNQVLEMRNVAASLDIWLTFEVLENGELERPLHPKEKVLEQALQWCKLPEPSAAYLLVRKVPIGEGSCLFTGAKRESPKCGLLKCREEPPKLLGNKFHERYFVIRDRQLLLLKEKRSAKPEREWPLDVAKVYMGIRKKLKPPAPWGFTLSMDKQQLYLVCTGQAELWDWITSILKAQHDDQRPVIMRRRSSSDLAKQKFGTMPLVPLHGDSTDATMLSANQTLRRLHTRRTLSMFFPMKVHQDSLEEQQEKEVDTEPVYEEVGNFPELATLELQRGLLADPSPVPTMDRSQKPSSSPEQPPAPVLRSSLPPSPAQRLPAPSVTKAVSLERGLNLECDKAPSCGLRATLTASLERNLEPPTVLARDQEQTAVLGHSSSPETSISTKKRSAQPSSPISDKLIQELSSIILKKSDGQTQGTGTGTGSGQPVT", "length": 1736, "header": "tr|A0A8V0YIJ2-1|A0A8V0YIJ2_CHICK Isoform 1 of ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3 OS=Gallus gallus OX=9031 GN=ARAP3 PE=4 SV=1 CANONICAL=A0A8V0YIJ2-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YBL6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIJ2/entry#A0A8V0YBL6-1", "sequence": { "sequence": "MSSPCTPDSDIADWLATIHLERYRDLFKQHGFHLARDVAALDNKQLQQLGITATGHRKRILNLAEKTRLLGDPHPRAPQMGEDATKAEPGVAADAFGMQKCNAVPRQVMLLQKDLDPPLVRPVPKPRTVFYRPKLEQGSAATPAAHSQDRDGTAGAFVVLEGFVPGESSTDLESPGATMGTGTSRLGAQEEAQLPAVPDHGETQETPEKPCLCVPSVPPRLRHRVPVAELSAVGATVRPPSVPGVGQGRMEMVSNVIYEGFKQPLAPVEDSGQEDSPRGQALTQDPSPQELTQLAEKPKASWPGGGLPPIPQRPASKPEFSEPPISPYSETTFGNTVPAREQKGTDVPSGQSYEAVTELEQETQRTSSEYSSEGRSEDEETRTRLIERIVQNDTEGYSTVDAPRAKGTPFSLPPHLYPDEVLDDLTISPYASYTSLSEPRPAMLSGWLDKLSPQGNYVFQRRYVRFDGKNLMYFSSEKEPYPKGVIPLPVIEMVRSTKDNKFQVVTSHRIFVFRAENEAQRNEWCSTLQQKVMDQHLVGTRPRPLNTAHCQKSGTLELKGQKSKVFAVLSLPEMWLYKSEQFFKMGIGICMIEMRGSTIREAKNRTFELITPSKIFSFVAESEREKREWMEALQEAIAETLYDYEVAEKIWSNKANRYCADCWAHSPDWASINLCVVICKQCAGQHRSLGSNISKVQSLKLDTSVWSNEIVQLFIVLGNDRANRFWAARIPATEVLHPDASTEQRRDFISRKYRDGRYRLPHPHYASHEDVLQALCTAVAGPSLLKTILQFFSAAEAGLAADPTAPDITPVAEPWWDLESKRNHAGVPGPEGVYNEITQPVAHSGYLHRSMAHPRLPGAKKSRDDFQRVWCSLERALLIFETEKCTEPLSHIQSGDLLSLGVSRAQPISSPGPTERFHFILELFLTGEKVQQLGADSADTLQAWASAIGKWFTPVSCHCLLGYEFQRVGQLRYKCMLNPERWQRAFFILQKAHLFICPAEEDGAEDSINLRRLQELSLVPPAEMPEKKEMLVLVEMGRTFYLQGLSRADTAAWYADIQASAGGRGNALRDQQLSRGDIPIIVDSCIAFITQYGLRHEGIYRKNGAKSRIKVLMEEFRRDARNVKLRISDNFIEDVTDVLKRFFRELEDPVFTLELHPQWKEAAAISSKPQRLERYKELIHRLPRLNRKTLAALIGHLYRVQKCADLNQMSTKNLSLLFAPSLFQTDGKGEHEVKVMEDLIDNYVTIFNIDEDQVSQMDLENSLITTWKDTQLSQAGDLIIEVYLEQKLPDCCVTLKVSPTMTAEELTNQVLEMRNVAASLDIWLTFEVLENGELERPLHPKEKVLEQALQWCKLPEPSAAYLLVRKVPIGEGSCLFTGAKRESPKCGLLKCREEPPKLLGNKFHERYFVIRDRQLLLLKEKRSAKPEREWPLDVAKVYMGIRKKLKPPAPWGFTLSMDKQQLYLVCTGQAELWDWITSILKAQHDDQRPVIMRRRSSSDLAKQKFGTMPLVPLHGDSTDATMLSANQTLRRLHTRRTLSMFFPMKVHQDSLEEQQEKEVDTEPVYEEVGNFPELATLELQRGLLADPSPVPTMDRSQKPSSSPEQPPAPVLRSSLPPSPAQRLPAPSVTKAVSLERGLNLECDKAPSCGLRATLTASLERNLEPPTVLARDQEQTAVLGHSSSPETSISTKKRSAQPSSPISDKLIQELSSIILKKSDGQTQGTGTGTGSGQPVT", "length": 1735, "header": "tr|A0A8V0YBL6-1|A0A8V0YBL6_CHICK Computationally mapped isoform of ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3 OS=Gallus gallus OX=9031 GN=ARAP3 PE=4 SV=1 CANONICAL=A0A8V0YIJ2-1" }, "locus": { "chromosome": "13", "start_pos": 1594269, "end_pos": 1580119, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027673.1", "url": "https://www.ensembl.org/id/ENSGALT00010027673.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015858.1", "url": "https://www.ensembl.org/id/ENSGALP00010015858.1" } ] } }, { "isoform_ac": "A0A8V0YIJ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIJ2/entry#A0A8V0YIJ2-1", "sequence": { "sequence": "MSSPCTPDSDIADWLATIHLERYRDLFKQHGFHLARDVAALDNKQLQQLGITATGHRKRILNLAEKTRLLGDPHPRAPQMGEDATKAEPGVAADAFGMQKCNAVPRQVMLLQKDLDPPLVRPVPKPRTVFYRPKLEQGSAATPAAHSQDRDGTAGAFVVLEGFVPGESSTDLESPGATMGTGTSRLGAQEEAQLPAVPDHGETQETPEKPCLCVPSVPPRLRHRVPVAELSAVGATVRPPSVPGVGQGRMEMVSNVIYEGFKQPLAPVEDSGQEDSPRGQALTQDPSPQELTQLAEKPNRASWPGGGLPPIPQRPASKPEFSEPPISPYSETTFGNTVPAREQKGTDVPSGQSYEAVTELEQETQRTSSEYSSEGRSEDEETRTRLIERIVQNDTEGYSTVDAPRAKGTPFSLPPHLYPDEVLDDLTISPYASYTSLSEPRPAMLSGWLDKLSPQGNYVFQRRYVRFDGKNLMYFSSEKEPYPKGVIPLPVIEMVRSTKDNKFQVVTSHRIFVFRAENEAQRNEWCSTLQQKVMDQHLVGTRPRPLNTAHCQKSGTLELKGQKSKVFAVLSLPEMWLYKSEQFFKMGIGICMIEMRGSTIREAKNRTFELITPSKIFSFVAESEREKREWMEALQEAIAETLYDYEVAEKIWSNKANRYCADCWAHSPDWASINLCVVICKQCAGQHRSLGSNISKVQSLKLDTSVWSNEIVQLFIVLGNDRANRFWAARIPATEVLHPDASTEQRRDFISRKYRDGRYRLPHPHYASHEDVLQALCTAVAGPSLLKTILQFFSAAEAGLAADPTAPDITPVAEPWWDLESKRNHAGVPGPEGVYNEITQPVAHSGYLHRSMAHPRLPGAKKSRDDFQRVWCSLERALLIFETEKCTEPLSHIQSGDLLSLGVSRAQPISSPGPTERFHFILELFLTGEKVQQLGADSADTLQAWASAIGKWFTPVSCHCLLGYEFQRVGQLRYKCMLNPERWQRAFFILQKAHLFICPAEEDGAEDSINLRRLQELSLVPPAEMPEKKEMLVLVEMGRTFYLQGLSRADTAAWYADIQASAGGRGNALRDQQLSRGDIPIIVDSCIAFITQYGLRHEGIYRKNGAKSRIKVLMEEFRRDARNVKLRISDNFIEDVTDVLKRFFRELEDPVFTLELHPQWKEAAAISSKPQRLERYKELIHRLPRLNRKTLAALIGHLYRVQKCADLNQMSTKNLSLLFAPSLFQTDGKGEHEVKVMEDLIDNYVTIFNIDEDQVSQMDLENSLITTWKDTQLSQAGDLIIEVYLEQKLPDCCVTLKVSPTMTAEELTNQVLEMRNVAASLDIWLTFEVLENGELERPLHPKEKVLEQALQWCKLPEPSAAYLLVRKVPIGEGSCLFTGAKRESPKCGLLKCREEPPKLLGNKFHERYFVIRDRQLLLLKEKRSAKPEREWPLDVAKVYMGIRKKLKPPAPWGFTLSMDKQQLYLVCTGQAELWDWITSILKAQHDDQRPVIMRRRSSSDLAKQKFGTMPLVPLHGDSTDATMLSANQTLRRLHTRRTLSMFFPMKVHQDSLEEQQEKEVDTEPVYEEVGNFPELATLELQRGLLADPSPVPTMDRSQKPSSSPEQPPAPVLRSSLPPSPAQRLPAPSVTKAVSLERGLNLECDKAPSCGLRATLTASLERNLEPPTVLARDQEQTAVLGHSSSPETSISTKKRSAQPSSPISDKLIQELSSIILKKSDGQTQGTGTGTGSGQPVT", "length": 1736, "header": "tr|A0A8V0YIJ2-1|A0A8V0YIJ2_CHICK Isoform 1 of ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3 OS=Gallus gallus OX=9031 GN=ARAP3 PE=4 SV=1 CANONICAL=A0A8V0YIJ2-1" }, "locus": { "chromosome": "13", "start_pos": 1594269, "end_pos": 1580119, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027679.1", "url": "https://www.ensembl.org/id/ENSGALT00010027679.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015862.1", "url": "https://www.ensembl.org/id/ENSGALP00010015862.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 142, "start_aa": "Thr", "end_pos": 142, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr142", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 805, "start_aa": "Thr", "end_pos": 805, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr805", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 915, "start_aa": "Thr", "end_pos": 915, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr915", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:416196", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416196", "resource": "KEGG Pathway" }, { "id": "R-GGA-8980692", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8980692", "resource": "Reactome", "description": "RHOA GTPase cycle" }, { "id": "R-GGA-9013148", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013148", "resource": "Reactome", "description": "CDC42 GTPase cycle" }, { "id": "R-GGA-9013149", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013149", "resource": "Reactome", "description": "RAC1 GTPase cycle" }, { "id": "R-GGA-9013423", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013423", "resource": "Reactome", "description": "RAC3 GTPase cycle" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2JUX2-1", "protein_name": "Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3", "gene_name": "Arap3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAAPQDLDIAVWLAAVHLEQYADTFRRHGLATAGAAQRLGHEELRHLGISATGHRKRILRLLQSGSAEGFLDSQLDSTMEPTPSPAPDAQPSKPVPKPRTVFGLSNPANAQKPGLNPIFWNPEVSRNSECTQRSPPVLPSSSEQPSALNTMEMMPNAIYFGLDLRGRAQAAQDLTPDSSQATVPTPAFRPTTGTVHIMDPGCLYYGVQPVGVPGVPDRRDGRGVCQERAEHSRQDQETREDAGYASLELPGDSILSLPTQDAETSDDLISPYASFSSTADRPVPLLSGWLDKLSPQGNYVFQRRFVQFNGRSLMYFGSDKDPFPKGVIPLTAIEMTRSSKDNKFQVITGQRVFVFRTESEAQRDIWCSTLQSCLKEQRLLGHPRPPHPPRPLRTGMLELRGHKAKVFAALIPGELALYKSEQAFSLGIGICFIELQGCSVRETKSRSFDLLTPHRCFSFTAESGGARQSWAVALQEAVTETLSDYEVAEKVWSNPANRHCADCRASRPDWAAVNLGVVICKQCAGQHRALGSGISKVQSLKLDTSVWTNEIVQLFIVLGNDRANCFWAGALPPGEGLHPDAAPGPRGEFISRKYKLGLYRKPHPRHPDHSQLLQALCAAMVGPNLLKNMTQLLCVEASEGEEPLSPSALNGSLLSLLPSDSSPGVYNEVVVPATYRGFLYCGPISNKAGAPPLRRGRDAPPRLWCVLGAALEMFASESSSEPLSLLQPQDVVCLGISPPPADSGDLDRFPFSFELILTGGRIQHFATDGADSLEAWISAVGKWFSPLSCHQLLGPGLLRMGRLWLRSPSHAGLAPGLWLSGFGLLRGDHLFLCPAPGPGPPAPEDMVHLRRLQEISVVSAADTPDKKEHLVLVETGRTLYLQGEGRLDFAAWNTAIGGAAGGGGTGLQEQQMSRGDIPIIVDACISFVTQHGLRLEGVYRKGGARARSLRLLAEFRRDARSVKLRPREHFVEDVTDTLKRFFRELDDPVTSARLLPRWREAAELPQKNQRLEKYKEVISCLPRVNRRTLATLIGHLYRVQKCAALNQMCTRNLALLFAPSVFQTDGRGEHEVRVLQELIDGYISVFDIDSDQAAQIDLEVSLITTWKDVQLSQAGDLIMEVYIEQQLPDNCVTLKVSPTLTAEELTNQVLEMRGAASGTDLWVTFEILDHGELERPLHPKEKVLEQALQWCQLPEPCSASLLLRKVSMAHAGCLFTGVRRESPRVGLLRCREEPPRLLGSRFQERFFLVRGRCLLLLKEKKSSKPEREWSLEGAKVYLGIRKKLKPPTLWGFTLILEKMHLCLSCTDEEEMWDWTTSILKAQHDDQQSVVLRRHSSSDLARQKFGTMPLLPIRGDDSGATLLSANQTLRRLHNRRTLSMFFPMKSSQGSVEEQDELEEPVYEEPVYEEVGAFPELTKDMTSTWEWSTKSDTPLTSQRSFDQTPLTKASMLVQEERIPEPPPGPPSKSSPQARGSLEEQLLQELNNLILRKGEPATCPESPSQPTSPQSPSPTSLPTQTPSLPTQIPCASNPPSSQPLT", "length": 1538 }, "evidence": [ { "id": "A0A8V0YIJ2", "url": "https://omabrowser.org/oma/group/A0A8V0YIJ2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A480KQN9-1", "protein_name": "Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3", "gene_name": "ARAP3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAAPQDLDIAVWLAAVHLEQYADAFRRQGLATAGAARGLGHEELRQLGISATGHRKRILRLLQAGAAEGSPDPRPDSAMEPSPSPAAQAQPAKPVPKPRTVFGGLSGSTPTQRPGLTSALWRPEAAGSAESSPKSPSVPAFSAEQSSALNTVEMMPNAIYFGLDLRGGAQAAQDTAPDSAQAAAPTPALRPATGTVHIMDPGCLYYGVQPVGVPGAPDRREGRGVCQERAEHRLSRQDLEAREDAGYASLELPGAAPLSLPALDTDPSDDLISPYASFSSTADRPMPLLSGWLDKLSPQGNYVFQRRFVQFNGRSLMYFGSDKDPFPKGVIPLTAIEMTRSSKDNKFQVITGQRVFVFRTESEAQRDTWCSTLQSCLKEQRLLGHPRSPQPPRPLRTGMLELRGHKAKVFAALSPGELALYKSEQAFSLGIGICFIELQGCSVRETKSRSFDLLTPHRCFSFTAESGGARQSWAAALQEAVTETLSDYEVAEKIWSNRANRHCADCGASRPDWAAVNLGVVICKQCAGQHRALGSGISKVQSLKLDTSVWSNEIVQLFIVLGNDRANRFWAGALPAGEGLHPDSTPGSRGEFISRKYRLGLFRKPHPQHPDHSQLLQALCAAVAGPNLLKNMTQLLCVEAFEGEESWSPSALDGSFPGVLSSDPSPGVYNEVVVPATYSSFLYCSPISNKAGPPPPRRGRDAPPRLWCVLGAALEMFVSESSPEPLSLIQPQDVVCLGVSPPPTDPGDLDRFPFAFELILTGGRIQHFGTDGADSLEAWTSAVGKWFSPLSCHQLLGPGLLRLGRLWLRSPSHTALAPGLWLAGFGLLRGDHLFLCPAPGPGPPAPEDMVHLRRLQEISVVSAADTPEKKEHLVLVETGRTLYLQAEGRLDFSAWSAAIGGAAGGGGTGLQEQQMSRGDIPIIVDACISFVTQHGLRLEGVYRKGGARARSLRLLAEFRRDARSVKLRPGEHFVEDVTDTLKRFFRELDDPVTSARLLPRWREAAELPQKHQRLEKYKEVIGSLPRVNRRTLATLIGHLYRVQKCAALNQMCTRNLALLFAPSIFQTDGRGEHEVRVLQELIDGYISVFDIDPDQVAQIDLEVSLITTWKDVQLSQAGDLIMEVFIEQQLPDNCVTLKVSPTLTAEELTNQVLEIRGTAAGTDLWVTFEIREHGELERPLHPKERVLEQALQWCQLPEPCSASLLLRKVSLAQAGCLFTGIRRESPRVGLLRCREEPPRLLGNRFQERFFLLRGRCLLLLKEKKSSKPEREWPLEGAKVYLGIRKKFKPPTPWGFTLILEKMHLQLSCTDEDEMWDWTTSILKAQYDDQQPVVLRRRSSSDLARQKFGTMPLLPIRGDDSGATLLSANQTLRRLHNRRTLSMFFPMKSSQGSVEEQEELEEPVYEEPVYEEVGAFPELTEDPFASFSTRREQTAKPETPLASQRSFDQPFLPKAGPLGWEERRPEPPPGPPSKSSPQAQGSLEEQLLQELSSLILRKGEATVGLGNPSQPSSPQPPSPSGLATQTPGFSTPAPCTSSPPPGQPLT", "length": 1545 }, "evidence": [ { "id": "A0A8V0YIJ2", "url": "https://omabrowser.org/oma/group/A0A8V0YIJ2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0AC58H7L2-1", "protein_name": "Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 isoform X1", "gene_name": "arap3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MHTMATIGPCSDAEDLLASIHLERYLDHFRQAGFLLARDFCHVDNAALNRVGVAATGHRKRILKLVEHIQLICQHQSKEPSLDRCNSESAIHDVTPVKAKPLSPSKPPGTTFQALRNSSAPNLCAQVKRSFSERSTSVVKPVPKPRTVFHKLRGDKFSLATQHEHRKSSQDPVVIDSSSLSSSTDTVKTATESKKGHLEPSLSCTALSPESEGPLPPVPPRLNRGIPPSTFRRMSGQERLSTPPLCTPPDSPSSYQCSPFTNTPGSPPSPPCSGLEMVSNEIYCGTLPDTPHVFWSRSVPVPPPRQEPSPSTENHSTLEKSNSSESSKRTSASAEEDDDMINPYCETVFHSKRQYQHSEVERSESKEKTSNKEDKLRDHGHHNHSWLKRLDSPGYCTVGESSHSFSLPHNLCSSEADEDIISPYASFTSLSERAAPILSGWLDKLSPQGYEPPPGLLLLISSRLCISFSGFSFCFLSVLYGRNYVFQKRYVKFDGKNLMYFGSEKDAYPKGVIPLAAIQMARLAKDNKFEIVTSHRTFVFRADNDVQRSKWCSTLQERVKEQLVFGRPRFGPGSHCQKSGFLELKGTKSKIYTAIIMEQIWLYKSEQCFKNGIGITVIEARGATIRDGKGKSFDLITPYKTFSFTAETDREKRDWMEALQESIAETLSDYEVAEKIWSNRSNKICADCKAINPDWASINLCVVICKNCAGQHRGLGTMVSKVQSLKLDTSVWSNEIVQLFIMLGNDRANEFWAARLPVSEELDCDATPEQRREFISHKYKEGRYRHPHPSFSSQEELLKALCTAVTEQNLLKTVTQIFAEAEAARLADANGNDKRVSPHYSYTQSADSCVYDEIMQPILYSGFLYKSGSLNKGTLSRRTRDADFQKYWCSVEKSILFYESDRCHEPSMKIDVKDIICLGVSRPDSSNNSGFIDKFRYTFELYLMSDKLVQFGLETPDALHSWARAIGKATTPLSCHCLLAREFERVGVLRYKAMLDPQQWKEGFFVLQKSNLFICPGNDGAAEDIINLKRLQELSIASEMENHEKKDILVLVEKGRTLHLQGTGRTDFSLWYADIQKAAGGKGNTLKDQQLSRNDIPIIVDSCIAFITQYGLGHEGIYRKNGAKSRIKLLMEEFRKDARNVKLRIGDNFIEDVTDVLKRFFREIDDPIFMADLHPFWKEAAKIPLKTQRLDRYKELIRGLPRVNRTTLAALISHLYRVQKCADLNQMCTKNLSLLFAPSLFQTDGKGEHEVKIIEDLIDNYLYIFDVDEEHQTQIDLEISLITTWRDTQLSQAGDLIIEVYLEEKIPDCCITLKVSPTMCAEELTNQVLYMRNIPAGEKDVWMTFEAIEDGELERPLHPKEKVLEQALQWCKMADPSSAYLVVKKVPRGEAIDIFTAYKSEIVKSGVLKCREEPPKLLQGNKFQERSFQIKDHKLLLMKDKKSNKPEKEWQLKTLKIYMGIRKKLKPPTKWGLTVLLDKQQLYLSCSCETELWDWMTNLLKAQNDDLRPPVMRRHSSSDISKQKFGTMPLVPIRGEESNTNSTMLSANQTLRKLHTRRALSMFFPMKIQQQDSFEERIEIPEPLYEEVGDFGLQVLKSLETSFLSSGHAETQEVPMRPISLGQRKTTSLDRMLGSRPFVSSGESLDALSHDGSSDSLPIPGRHRAHRSCSPQQELLLQELSTMFCKKPESDEPESLT", "length": 1697 }, "evidence": [ { "id": "A0A8V0YIJ2", "url": "https://omabrowser.org/oma/group/A0A8V0YIJ2/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q8R5G7-1", "protein_name": "Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3", "gene_name": "Arap3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAPQDLDIAVWLALVHLEQYADTFRRHGLATAGAAQHLGHEELRHLGISATGHRKRILRLLRAGSAEGFLDSHLDNTMEPTPSPAPDAQPPKPVPKPRTVFGLSNPATAQRPGLSPIFWDPEVSRNSECTQRSSPLLPSSSEQPSVPNTMEMMPNAIYFGLDLRGRAQAAQDVTPDSSQATVPTPAFRPTTGTVHIMDPGCLYYGVQPVGIPGASDRRDGRGVCQERAEHRQDLETREDAGYASLELPGDSILSLPTQDAETSDDLISPYASFSSTADRPVPLLSGWLDKLSPQGNYVFQRRFVQFNGRSLMYFGSDKDPFPKGVIPLTAIEMTRSSKDNKFQVITGQRVFVFRTESEAQRDLWCSTLQSCLKEQRLLGHPRPPHPPRPLRTGTLELRGHKAKVFAALIPGELALYKSEQAFSLGIGICFIELQGCSVRETKSRSFDLLTPHRCFSFTAESGGARQSWAAALQEAVTETLSDYEVAEKVWSNPANRHCADCRASRPDWAAVNLGVVICKQCAGQHRALGSGISKVQSLKLDTSVWSNEIVQLFIVLGNDRANCFWAGALPPGEGLHPDSAPGPRGEFISRKYKLGLFRKPHPRHPDHSQLLQALCAAMAGPNLLKNMAQLLCVETSEGEEPLSPSALNGSLLSLLPSDSPGVYNEVVVPATYRGFLYCGSISNKAGAPPLRRGRDAPPRLWCVLGAALEMFASESSPEPLSLLQPQDIVCLGVSPPPADPGDLDRFPFSFELILTGGRIQHFATDGADSLEAWISAVGKWFSPLSCHQLLGPGLLRMGRLWLRSPSHAGLAPGLWLSGFGLLRGDHLFLCPAPGPGPPAPEDMVHLRRLQEISVVSAADTPDKKEHLVLVETGRTLYLQGEGRLDFAAWNTAIGGAAGGGGTGLQEQQMSRGDIPIIVDACISFVTQHGLRLEGVYRKGGARARSLRLLAEFRRDARSVKLRPREHFVEDVTDTLKRFFRELDDPVTSARLLPRWREAAELSQKNQRLEKYKEVISCLPRVNRRTLATLIGHLYRVQKCASLNQMCTRNLALLFAPSVFQTDGRGEHEVRVLQELIDGYISVFDIDSDQAAQIDLEVSLITTWKDVQLSQAGDLIMEVYIEQQLPDNCVTLKVSPTLTAEELTNQVLEMRGAASGTDLWVTFEILEHGELERPLHPKEKVLEQALQWCQLPEPCSASLLLRKVSMAHAGCLFTGVRRESPRVGLLRCREEPPRLLGNRFQERFFLVRGRCLLLLKEKKSSKPEREWSLEGAKVYLGIRKKLKPPTLWGFTLILEKMHLCLSCMDEEEMWDWTTSILKAQHDDQQSVVLRRRSSSDLARQKFGTMPLLPIRGDDSGATLLSANQTLRRLHNRRTLSMFFPMKSPQGSVEEQDELEEPVYEEPVYEEVGAFPELTKDTTFSSTWEWSAKSDPSLTSQRSFDQPPLSKASMLGHEERIPDPPPGPPSKSSSQARGSLEEQLLQELNNLILRKGEPASCPESSSQPTSPQAPSPTSLPTPTPSLPTQPPCTSNPPSSQPLT", "length": 1538 }, "evidence": [ { "id": "A0A8V0YIJ2", "url": "https://omabrowser.org/oma/group/A0A8V0YIJ2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8WWN8-1", "protein_name": "Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3", "gene_name": "ARAP3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAPQDLDIAVWLATVHLEQYADTFRRHGLATAGAARGLGHEELKQLGISATGHRKRILRLLQTGTEEGSLDPKSDSAMEPSPSPAPQAQPPKPVPKPRTVFGGLSGPATTQRPGLSPALGGPGVSRSPEPSPRPPPLPTSSSEQSSALNTVEMMPNSIYFGLDSRGRAQAAQDKAPDSSQISAPTPALRPTTGTVHIMDPGCLYYGVQPVGTPGAPDRRESRGVCQGRAEHRLSRQDLEAREDAGYASLELPGDSTLLSPTLETEETSDDLISPYASFSFTADRLTPLLSGWLDKLSPQGNYVFQRRFVQFNGRSLMYFGSDKDPFPKGVIPLTAIEMTRSSKDNKFQVITGQRVFVFRTESEAQRDMWCSTLQSCLKEQRLLGHPRPPQPPRPLRTGMLELRGHKAKVFAALSPGELALYKSEQAFSLGIGICFIELQGCSVRETKSRSFDLLTPHRCFSFTAESGGARQSWAAALQEAVTETLSDYEVAEKIWSNRANRQCADCGSSRPDWAAVNLGVVICKQCAGQHRALGSGISKVQSLKLDTSVWSNEIVQLFIVLGNDRANRFWAGTLPPGEGLHPDATPGPRGEFISRKYRLGLFRKPHPQYPDHSQLLQALCAAVARPNLLKNMTQLLCVEAFEGEEPWFPPAPDGSCPGLLPSDPSPGVYNEVVVRATYSGFLYCSPVSNKAGPSPPRRGRDAPPRLWCVLGAALEMFASENSPEPLSLIQPQDIVCLGVSPPPTDPGDRFPFSFELILAGGRIQHFGTDGADSLEAWTSAVGKWFSPLSCHQLLGPGLLRLGRLWLRSPSHTAPAPGLWLSGFGLLRGDHLFLCSAPGPGPPAPEDMVHLRRLQEISVVSAADTPDKKEHLVLVETGRTLYLQGEGRLDFTAWNAAIGGAAGGGGTGLQEQQMSRGDIPIIVDACISFVTQHGLRLEGVYRKGGARARSLRLLAEFRRDARSVKLRPGEHFVEDVTDTLKRFFRELDDPVTSARLLPRWREAAELPQKNQRLEKYKDVIGCLPRVNRRTLATLIGHLYRVQKCAALNQMCTRNLALLFAPSVFQTDGRGEHEVRVLQELIDGYISVFDIDSDQVAQIDLEVSLITTWKDVQLSQAGDLIMEVYIEQQLPDNCVTLKVSPTLTAEELTNQVLEMRGTAAGMDLWVTFEIREHGELERPLHPKEKVLEQALQWCQLPEPCSASLLLKKVPLAQAGCLFTGIRRESPRVGLLRCREEPPRLLGSRFQERFFLLRGRCLLLLKEKKSSKPEREWPLEGAKVYLGIRKKLKPPTPWGFTLILEKMHLYLSCTDEDEMWDWTTSILKAQHDDQQPVVLRRHSSSDLARQKFGTMPLLPIRGDDSGATLLSANQTLRRLHNRRTLSMFFPMKSSQGSVEEQEELEEPVYEEPVYEEVGAFPELIQDTSTSFSTTREWTVKPENPLTSQKSLDQPFLSKSSTLGQEERPPEPPPGPPSKSSPQARGSLEEQLLQELSSLILRKGETTAGLGSPSQPSSPQSPSPTGLPTQTPGFPTQPPCTSSPPSSQPLT", "length": 1544 }, "evidence": [ { "id": "A0A8V0YIJ2", "url": "https://omabrowser.org/oma/group/A0A8V0YIJ2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIJ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIJ2" } ], "pmid": "" }, { "name": "phosphatidylinositol-3,4,5-trisphosphate binding", "id": "GO:0005547", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005547", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIJ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIJ2" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIJ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIJ2" } ], "pmid": "" }, { "name": "phosphatidylinositol-3,4-bisphosphate binding", "id": "GO:0043325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043325", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIJ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIJ2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIJ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIJ2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIJ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIJ2" } ], "pmid": "" }, { "name": "regulation of actin cytoskeleton organization", "id": "GO:0032956", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032956", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIJ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIJ2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1214, "end_pos": 1216, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1527, "end_pos": 1529, "annotation": "n_glycosylation_sequon" }, { "start_pos": 393, "end_pos": 395, "annotation": "n_glycosylation_sequon" }, { "start_pos": 605, "end_pos": 607, "annotation": "n_glycosylation_sequon" }, { "start_pos": 693, "end_pos": 695, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YIJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIJ2" }, { "id": "PS50115", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50115" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Arf-GAP", "eco_id": "ECO_0000259", "start_pos": 636, "end_pos": 767, "start_aa": "Glu", "end_aa": "Ala", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0YIJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIJ2" }, { "id": "PS50003", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50003" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PH", "eco_id": "ECO_0000259", "start_pos": 442, "end_pos": 534, "start_aa": "Pro", "end_aa": "Met", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0YIJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIJ2" }, { "id": "PS50200", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50200" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ras-associating", "eco_id": "ECO_0000259", "start_pos": 1277, "end_pos": 1370, "start_aa": "Gly", "end_aa": "Ile", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0YIJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIJ2" }, { "id": "PS50238", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50238" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Rho-GAP", "eco_id": "ECO_0000259", "start_pos": 1067, "end_pos": 1248, "start_aa": "Asn", "end_aa": "Phe", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0YIJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIJ2" }, { "id": "PS50105", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50105" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SAM", "eco_id": "ECO_0000259", "start_pos": 6, "end_pos": 70, "start_aa": "Thr", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 142, 805, 915 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1214, "end_pos": 1216 }, { "start_pos": 1527, "end_pos": 1529 }, { "start_pos": 393, "end_pos": 395 }, { "start_pos": 605, "end_pos": 607 }, { "start_pos": 693, "end_pos": 695 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 3 }, { "field": "total_sites", "count": 3 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 3 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 3 }, { "field": "exact_o_linked_sites", "count": 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"https://www.uniprot.org/uniprotkb/A0A8V0YR88-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C4P2", "url": "https://www.uniprot.org/uniprotkb/E1C4P2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C4P2-1", "url": "https://www.uniprot.org/uniprotkb/E1C4P2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPSRRGRAVCCGQGCPDYVYFENSSSNPYLIRRIEELNKTANGNVEAKVVCFYRRRDISSTLIVLADKHAREMEEEMENPEMVDLPEKQKHQLRHRELFLSRQLESLPATHIRGKCSVTLLNETESLKSYLEREDFFFYSLVYDPQQKTLLADKGEIRVGNRYQADITDLLKEGEDDGRDQSKLETKVWEAFNPLVDKQIDQFLVVARSVGTFARALDCSSSVRQPSLHMSAAAASRDITLFHAMDTLHKNVYDISKAISALVPQGGPVLCRDEMEEWSASEANLFEEALEKYGKDFTDIQQDFLPWKSLTSIIEYYYMWKTTDRYVQQKRLKAAEAESKLKQVYIPNYNKPNPNQINVNNVKPGVVNGTGVQAQNAAAGRACESCYTTQSYQWYSWGPPNMQCRLCASCWTYWKKYGGLKMPTRLDGERPGPNRNNLSPHGVPVRNSGSPKFAMKTRQAFYLHTTKLTRIARRLCRDILRPWHAARHPYLPINSAAIKAECTARLPEASENPLLLKQVVRKPLEAVLRYLESHPCPPKPDPAKSLSSSLNNLTPAKFTPVINNGSPTILGKRSYEQHNGMDGNMKKRLLMPSRGLPNHGQTRQMGPSRNLLLNGKSYPTKVRLIRGGSMPPVKRRRMNWIDAPDDVFYMATEETRKIRKLLSSSEAKRAARRPYKPIILRPIQAVQLRQPMNDEPIIIED", "length": 701, "header": "tr|A0A8V0YIL2-1|A0A8V0YIL2_CHICK Isoform 1 of Metastasis associated 1 OS=Gallus gallus OX=9031 GN=MTA1 PE=1 SV=1 CANONICAL=A0A8V0YIL2-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YIL2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIL2/entry#A0A8V0YIL2-1", "sequence": { "sequence": "MPSRRGRAVCCGQGCPDYVYFENSSSNPYLIRRIEELNKTANGNVEAKVVCFYRRRDISSTLIVLADKHAREMEEEMENPEMVDLPEKQKHQLRHRELFLSRQLESLPATHIRGKCSVTLLNETESLKSYLEREDFFFYSLVYDPQQKTLLADKGEIRVGNRYQADITDLLKEGEDDGRDQSKLETKVWEAFNPLVDKQIDQFLVVARSVGTFARALDCSSSVRQPSLHMSAAAASRDITLFHAMDTLHKNVYDISKAISALVPQGGPVLCRDEMEEWSASEANLFEEALEKYGKDFTDIQQDFLPWKSLTSIIEYYYMWKTTDRYVQQKRLKAAEAESKLKQVYIPNYNKPNPNQINVNNVKPGVVNGTGVQAQNAAAGRACESCYTTQSYQWYSWGPPNMQCRLCASCWTYWKKYGGLKMPTRLDGERPGPNRNNLSPHGVPVRNSGSPKFAMKTRQAFYLHTTKLTRIARRLCRDILRPWHAARHPYLPINSAAIKAECTARLPEASENPLLLKQVVRKPLEAVLRYLESHPCPPKPDPAKSLSSSLNNLTPAKFTPVINNGSPTILGKRSYEQHNGMDGNMKKRLLMPSRGLPNHGQTRQMGPSRNLLLNGKSYPTKVRLIRGGSMPPVKRRRMNWIDAPDDVFYMATEETRKIRKLLSSSEAKRAARRPYKPIILRPIQAVQLRQPMNDEPIIIED", "length": 701, "header": "tr|A0A8V0YIL2-1|A0A8V0YIL2_CHICK Isoform 1 of Metastasis associated 1 OS=Gallus gallus OX=9031 GN=MTA1 PE=1 SV=1 CANONICAL=A0A8V0YIL2-1" }, "locus": { "chromosome": "8", "start_pos": 4074282, "end_pos": 4016563, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031857.1", "url": "https://www.ensembl.org/id/ENSGALT00010031857.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018661.1", "url": "https://www.ensembl.org/id/ENSGALP00010018661.1" } ] } }, { "isoform_ac": "A0A8V0YJD9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIL2/entry#A0A8V0YJD9-1", "sequence": { "sequence": "MEMWKQRWCVSTEEETFQAHLLYWQINTQKWKKRWKTQKWSTCQRNRSISYDIVSYFSRDSWNPCQPHTLGKCSVTLLNETESLKSYLEREDFFFYSLVYDPQQKTLLADKGEIRVGNRYQADITDLLKEGEDDGRDQSKLETKVWEAFNPLVDKQIDQFLVVARSVGTFARALDCSSSVRQPSLHMSAAAASRDITLFHAMDTLHKNVYDISKAISALVPQGGPVLCRDEMEEWSASEANLFEEALEKYGKDFTDIQQDFLPWKSLTSIIEYYYMWKTTDRYVQQKRLKAAEAESKLKQVYIPNYNKPNPNQINVNNVKPGVVNGTGVQAQNAAAGRACESCYTTQSYQWYSWGPPNMQCRLCASCWTYWKKYGGLKMPTRLDGERPGPNRNNLSPHGVPVRNSGSPKFAMKTRQAFYLHTTKLTRIARRLCRDILRPWHAARHPYLPINSAAIKAECTARLPEASENPLLLKQVVRKPLEAVLRYLESHPCPPKPDPAKSLSSSLNNLTPAKFTPVINNGSPTILGKRSYEQHNGMDGLPNHGQTRQMGPSRNLLLNGKSYPTKVRLIRGGSMPPVKRRRMNWIDAPDDVFYMATEETRKIRKLLSSSEAKRAARRPYKPIILRPIQAVQLRQPMNDEPIIIED", "length": 646, "header": "tr|A0A8V0YJD9-1|A0A8V0YJD9_CHICK Computationally mapped isoform of Metastasis associated 1 OS=Gallus gallus OX=9031 GN=MTA1 PE=1 SV=1 CANONICAL=A0A8V0YIL2-1" }, "locus": { "chromosome": "8", "start_pos": 4069478, "end_pos": 4016563, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031876.1", "url": "https://www.ensembl.org/id/ENSGALT00010031876.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018679.1", "url": "https://www.ensembl.org/id/ENSGALP00010018679.1" } ] } }, { "isoform_ac": "A0A8V0YLB2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIL2/entry#A0A8V0YLB2-1", "sequence": { "sequence": "MFTSGDYVYFENSSSNPYLIRRIEELNKTANGNVEAKVVCFYRRRDISSTLIVLADKHAREMEEEMENPEMVDLPEKQKHQLRHRELFLSRQLESLPATHIRGKCSVTLLNETESLKSYLEREDFFFYSLVYDPQQKTLLADKGEIRVGNRYQADITDLLKEGEDDGRDQSKLETKVWEAFNPLVDKQIDQFLVVARSVGTFARALDCSSSVRQPSLHMSAAAASRDITLFHAMDTLHKNVYDISKAISALVPQGGPVLCRDEMEEWSASEANLFEEALEKYGKDFTDIQQDFLPWKSLTSIIEYYYMWKTTDRYVQQKRLKAAEAESKLKQVYIPNYNKPNPNQINVNNVKPGVVNGTGVQAQNAAAGRACESCYTTQSYQWYSWGPPNMQCRLCASCWTYWKKYGGLKMPTRLDGERPGPNRNNLSPHGVPVRNSGSPKFAMKTRQAFYLHTTKLTRIARRLCRDILRPWHAARHPYLPINSAAIKAECTARLPEASENPLLLKQVVRKPLEAVLRYLESHPCPPKPDPAKSLSSSLNNLTPAKFTPVINNGSPTILGKRSYEQHNGMDGLPNHGQTRQMGPSRNLLLNGKSYPTKVRLIRGGSMPPVKRRRMNWIDAPDDVFYMATEETRKIRKLLSSSEAKRAARRPYKPIILRPIQAVQLRQPMNDEPIIIED", "length": 678, "header": "tr|A0A8V0YLB2-1|A0A8V0YLB2_CHICK Computationally mapped isoform of Metastasis associated 1 OS=Gallus gallus OX=9031 GN=MTA1 PE=1 SV=1 CANONICAL=A0A8V0YIL2-1" }, "locus": { "chromosome": "8", "start_pos": 4078119, "end_pos": 4016563, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031866.1", "url": "https://www.ensembl.org/id/ENSGALT00010031866.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018670.1", "url": "https://www.ensembl.org/id/ENSGALP00010018670.1" } ] } }, { "isoform_ac": "A0A8V0YR78-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIL2/entry#A0A8V0YR78-1", "sequence": { "sequence": "MAANMYRVGDYVYFENSSSNPYLIRRIEELNKTANGNVEAKVVCFYRRRDISSTLIVLADKHAREMEEEMENPEMVDLPEKQKHQLRHRELFLSRQLESLPATHIRGKCSVTLLNETESLKSYLEREDFFFYSLVYDPQQKTLLADKGEIRVGNRYQADITDLLKEGEDDGRDQSKLETKVWEAFNPLVDKQIDQFLVVARSVGTFARALDCSSSVRQPSLHMSAAAASRDITLFHAMDTLHKNVYDISKAISALVPQGGPVLCRDEMEEWSASEANLFEEALEKYGKDFTDIQQDFLPWKSLTSIIEYYYMWKTTDRYVQQKRLKAAEAESKLKQVYIPNYNKPNPNQINVNNVKPGVVNGTGVQAQNAAAGRACESCYTTQSYQWYSWGPPNMQCRLCASCWTYWKKYGGLKMPTRLDGERPGPNRNNLSPHGVPVRNSGSPKFAMKTRQAFYLHTTKLTRIARRLCRDILRPWHAARHPYLPINSAAIKAECTARLPEASENPLLLKQVVRKPLEAVLRYLESHPCPPKPDPAKSLSSSLNNLTPAKFTPVINNGSPTILGKRSYEQHNGMDGNMKKRLLMPSRGLPNHGQTRQMEVGVRVCLLRMLLLLCSFIIIIFFWSNNDSFHPRC", "length": 633, "header": "tr|A0A8V0YR78-1|A0A8V0YR78_CHICK Computationally mapped isoform of Metastasis associated 1 OS=Gallus gallus OX=9031 GN=MTA1 PE=1 SV=1 CANONICAL=A0A8V0YIL2-1" }, "locus": { "chromosome": "8", "start_pos": 4081161, "end_pos": 4022749, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031864.1", "url": "https://www.ensembl.org/id/ENSGALT00010031864.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018668.1", "url": "https://www.ensembl.org/id/ENSGALP00010018668.1" } ] } }, { "isoform_ac": "A0A8V0YR88-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIL2/entry#A0A8V0YR88-1", "sequence": { "sequence": "MAANMYRVGDYVYFENSSSNPYLIRRIEELNKTANGNVEAKVVCFYRRRDISSTLIVLADKHAREMEEEMENPEMVDLPEKQKHQLRHRELFLSRQLESLPATHIRGKCSVTLLNETESLKSYLEREDFFFYSLVYDPQQKTLLADKGEIRVGNRYQADITDLLKEGEDDGRDQSKLETKVWEAFNPLVDKQIDQFLVVARSVGTFARALDCSSSVRQPSLHMSAAAASRDITLFHAMDTLHKNVYDISKAISALVPQGGPVLCRDEMEEWSASEANLFEEALEKYGKDFTDIQQDFLPWKSLTSIIEYYYMWKTTDRYVQQVRKSESPLAFQENNKPNPNQINVNNVKPGVVNGTGVQAQNAAAGRACESCYTTQSYQWYSWGPPNMQCRLCASCWTYWKKYGGLKMPTRLDGERPGPNRNNLSPHGVPVRNSGSPKFAMKTRQAFYLHTTKLTRIARRLCRDILRPWHAARHPYLPINSAAIKAECTARLPEASENPLLLKQVVRKPLEAVLRYLESHPCPPKPDPAKSLSSSLNNLTPAKFTPVINNGSPTILGKRSYEQHNGMDGNMKKRLLMPSRGTKPKLAAQWEIIPNKSPINSWWIHASSEKEEDELD", "length": 616, "header": "tr|A0A8V0YR88-1|A0A8V0YR88_CHICK Computationally mapped isoform of Metastasis associated 1 OS=Gallus gallus OX=9031 GN=MTA1 PE=1 SV=1 CANONICAL=A0A8V0YIL2-1" }, "locus": { "chromosome": "8", "start_pos": 4081161, "end_pos": 4020301, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031875.1", "url": "https://www.ensembl.org/id/ENSGALT00010031875.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018678.1", "url": "https://www.ensembl.org/id/ENSGALP00010018678.1" } ] } }, { "isoform_ac": "E1C4P2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIL2/entry#E1C4P2-1", "sequence": { "sequence": "MAANMYRVGDYVYFENSSSNPYLIRRIEELNKTANGNVEAKVVCFYRRRDISSTLIVLADKHAREMEEEMENPEMVDLPEKQKHQLRHRELFLSRQLESLPATHIRGKCSVTLLNETESLKSYLEREDFFFYSLVYDPQQKTLLADKGEIRVGNRYQADITDLLKEGEDDGRDQSKLETKVWEAFNPLVDKQIDQFLVVARSVGTFARALDCSSSVRQPSLHMSAAAASRDITLFHAMDTLHKNVYDISKAISALVPQGGPVLCRDEMEEWSASEANLFEEALEKYGKDFTDIQQDFLPWKSLTSIIEYYYMWKTTDRYVQQKRLKAAEAESKLKQVYIPNYNKPNPNQINVNNVKPGVVNGTGVQAQNAAAGRACESCYTTQSYQWYSWGPPNMQCRLCASCWTYWKKYGGLKMPTRLDGERPGPNRNNLSPHGVPVRNSGSPKFAMKTRQAFYLHTTKLTRIARRLCRDILRPWHAARHPYLPINSAAIKAECTARLPEASENPLLLKQVVRKPLEAVLRYLESHPCPPKPDPAKSLSSSLNNLTPAKFTPVINNGSPTILGKRSYEQHNGMDGNMKKRLLMPSRGTKPKLAAQWEIIPNKSPINSWWIHASSEKEEDELD", "length": 623, "header": "tr|E1C4P2-1|E1C4P2_CHICK Computationally mapped isoform of Metastasis associated 1 OS=Gallus gallus OX=9031 GN=MTA1 PE=1 SV=3 CANONICAL=A0A8V0YIL2-1" }, "locus": { "chromosome": "8", "start_pos": 4081161, "end_pos": 4020301, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031872.1", "url": "https://www.ensembl.org/id/ENSGALT00010031872.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018675.1", "url": "https://www.ensembl.org/id/ENSGALP00010018675.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:429060", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:429060", "resource": "KEGG Pathway" }, { "id": "R-GGA-3232118", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3232118", "resource": "Reactome", "description": "SUMOylation of transcription factors" }, { "id": "R-GGA-73762", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-73762", "resource": "Reactome", "description": "RNA Polymerase I Transcription Initiation" }, { "id": "R-GGA-8943724", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8943724", "resource": "Reactome", "description": "Regulation of PTEN gene transcription" }, { "id": "R-GGA-9937850", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9937850", "resource": "Reactome", "description": "NuRD complex assembly" }, { "id": "R-GGA-9940951", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9940951", "resource": "Reactome", "description": "Interaction of NuRD complexes with transcription factors" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 7, "go_terms": [ { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIL2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIL2" } ], "pmid": "" }, { "name": "proteasome-mediated ubiquitin-dependent protein catabolic process", "id": "GO:0043161", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043161", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIL2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIL2" } ], "pmid": "" }, { "name": "double-strand break repair", "id": "GO:0006302", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006302", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIL2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIL2" } ], "pmid": "" }, { "name": "response to ionizing radiation", "id": "GO:0010212", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010212", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIL2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIL2" } ], "pmid": "" }, { "name": "negative regulation of gene expression, epigenetic", "id": "GO:0045814", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045814", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIL2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIL2" } ], "pmid": "" }, { "name": "positive regulation of protein autoubiquitination", "id": "GO:1902499", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902499", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIL2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIL2" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIL2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIL2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 8, "go_terms": [ { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIL2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIL2" } ], "pmid": "" }, { "name": "transcription coactivator activity", "id": "GO:0003713", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003713", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIL2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIL2" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIL2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIL2" } ], "pmid": "" }, { "name": "transcription corepressor activity", "id": "GO:0003714", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003714", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIL2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIL2" } ], "pmid": "" }, { "name": "histone deacetylase binding", "id": "GO:0042826", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042826", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIL2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIL2" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIL2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIL2" } ], "pmid": "" }, { "name": "RNA polymerase II-specific DNA-binding transcription factor binding", "id": "GO:0061629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061629", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIL2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIL2" } ], "pmid": "" }, { "name": "sequence-specific DNA binding", "id": "GO:0043565", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043565", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIL2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIL2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "nuclear envelope", "id": "GO:0005635", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005635", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIL2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIL2" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIL2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIL2" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIL2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIL2" } ], "pmid": "" }, { "name": "microtubule", "id": "GO:0005874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005874", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIL2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIL2" } ], "pmid": "" }, { "name": "NuRD complex", "id": "GO:0016581", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016581", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIL2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIL2" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIL2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIL2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 122, "end_pos": 124, "annotation": "n_glycosylation_sequon" }, { "start_pos": 23, "end_pos": 25, "annotation": "n_glycosylation_sequon" }, { "start_pos": 368, "end_pos": 370, "annotation": "n_glycosylation_sequon" }, { "start_pos": 38, "end_pos": 40, "annotation": "n_glycosylation_sequon" }, { "start_pos": 437, "end_pos": 439, "annotation": "n_glycosylation_sequon" }, { "start_pos": 552, "end_pos": 554, "annotation": "n_glycosylation_sequon" }, { "start_pos": 564, "end_pos": 566, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], 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"table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YJE4-1", "uniprot_ac": "A0A8V0YJE4", "uniprot_id": "A0A8V0YJE4_CHICK", "mass": { "chemical_mass": 97088.0, "monoisotopic_mass": 97088.0 }, "refseq": { "ac": "XP_015149577", "name": "E3 ubiquitin-protein ligase Jade-2 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015149577" }, "gene_names": [ { "name": "JADE2", "type": "recommended", "evidence": [ { "id": "A0A8V0YJE4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJE4" } ] }, { "name": "JADE2", "type": "synonym", "evidence": [ { "id": "XP_015149577", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015149577" } ] } ], "protein_names": [ { "name": "E3 ubiquitin-protein ligase Jade-2 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015149577", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015149577" } ] }, { "name": "Jade family PHD finger 2", "type": "synonym", "evidence": [ { "id": "A0A8V0YJE4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJE4/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 3% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052544.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015149577.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015149577", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015149577" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJE4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJE4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "JADE2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJE4", "locus": { "chromosome": "13", "start_pos": 15366208, "end_pos": 15420532, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013261", "url": "https://www.ensembl.org/id/ENSGALG00010013261" } ] } } ], "crossref": [ { "id": "A0A8V0YJE4", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YJE4", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15680", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15680", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd15705", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15705", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "416315", "url": "https://www.ncbi.nlm.nih.gov/gene/416315", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001965", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001965", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011011", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011011", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019542", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019542", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019786", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019786", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019787", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019787", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034732", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034732", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039548", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039548", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039549", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039549", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050701", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050701", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:416315", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416315", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "SMASCIT", "url": "https://omabrowser.org/oma/group/SMASCIT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YIN0", "url": "https://www.orthodb.org/?gene=A0A8V0YIN0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YJE4", "url": "https://www.orthodb.org/?gene=A0A8V0YJE4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13793", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13793", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13793:SF84", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13793:SF84", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10513", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10513", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13831", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13831", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13832", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13832", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015149577", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015149577", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YIN0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIN0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YIN0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIN0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJE4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJE4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJE4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJE4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLVPSPVLKCARRERRGCKHELFQMEEKRRKYSISSDNSDTTDSHTTSTSRCSKIPSTKSSWSRQKEKKPSEVFRTDLITAMKIPDSFQLSPEEYYVLADPWRQEWEKGVQVPASAEAIPEPVVRIIPQLENLPSPVSPSSLQGSEISEATRTYLQGMSRYDLDELDACWLELVNMELKEMEKPELDEITLERVLEELETMCYENMNIAIETEEGLGIEYDEDVVCDVCRSPEGEDGNEMVFCDKCNVCVHQACYGILKVPIGSWLCRTCALGVQPKCLLCPKRGGALKPTRSGTKWVHVSCALWIPEVSIGCPEKMEPITKISHIPASRWALSCSLCKECTGTCIQCSMPACVTAFHVTCAFDHNLDMRTILADNDEVKFKSFCLEHSTGATKLPEEARTEPDQAQLDLEKVTLRKQKLQQLEEDFYELVKPSEVAENLDLSESLVDFVYQYWKLKRKANSNKPLLTPKTDEVDNLAQQEQDVLYRRLKLFTHLRQDLERVRNLCYMVTRREKMKHTICKLQEQIFHLQMILIEKDLYPEQTGKKTKGKKSDPRRKGRDGRKNSPEKKEKRKSVNETVLGQLGLSTSFPIDGTFFNSWLAQSVQITAENMAMSEWSLNNAHHEDSTPGLSEELLQDEETLLSFMMDHSLRSPFKQSEAAKKVKSKTRTNTKKKPPRSGLTAVFRSQQEGSERWTNHGSDLSDDAAKPCAQESRPGRSEKGAARPADRRGSGEAKRAARRGPGPKGNDPPAPRGCAGEEEAVVAANGARPEPNPAAQVPDPVGSPKTVVRFKLPKESRGTRRSQPPKTDGPGGPPLRRFEAETDGYFSDAEMSDSDGEPRGGRAQRGQLEPGGEEIVRMSILAS", "length": 864, "header": "tr|A0A8V0YJE4-1|A0A8V0YJE4_CHICK Isoform 1 of Jade family PHD finger 2 OS=Gallus gallus OX=9031 GN=JADE2 PE=3 SV=1 CANONICAL=A0A8V0YJE4-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YIN0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJE4/entry#A0A8V0YIN0-1", "sequence": { "sequence": "MEEKRRKYSISSDNSDTTDSHTTSTSRCSKIPSTKSSWSRQKEKKPSEVFRTDLITAMKIPDSFQLSPEEYYVLADPWRQEWEKGVQVPASAEAIPEPVVRIIPQLENLPSPVSPSSLQGSEISEATRTYLQGMSRYDLDELDACWLELVNMELKEMEKPELDEITLERVLEELETMCYENMNIAIETEEGLGIEYDEDVVCDVCRSPEGEDGNEMVFCDKCNVCVHQACYGILKVPIGSWLCRTCALGVQPKCLLCPKRGGALKPTRSGTKWVHVSCALWIPEVSIGCPEKMEPITKISHIPASRWALSCSLCKECTGTCIQCSMPACVTAFHVTCAFDHNLDMRTILADNDEVKFKSFCLEHSTGATKLPEEARTEPDQAQLDLEKVTLRKQKLQQLEEDFYELVKPSEVAENLDLSESLVDFVYQYWKLKRKANSNKPLLTPKTDEVDNLAQQEQDVLYRRLKLFTHLRQDLERVRNLCYMVTRREKMKHTICKLQEQIFHLQMILIEKDLYPGLSTSFPIDGTFFNSWLAQSVQITAENMAMSEWSLNNAHHEDSTPGLSEELLQDEETLLSFMMDHSLRSPFKQSEAAKKVKSKTRTNTKKKPPRSGLTAVFRSQQEGSERWTNHGSDLSDDAAKPCAQESRPGRSEKGAARPADRRGSGEAKRAARRGPGPKGNDPPAPRGCAGEEEAVVAANGARPEPNPAAQVPDPVGSPKTVVRFKLPKESRGTRRSQPPKTDGPGGPPLRRFEAETDGYFSDAEMSDSDGEPRGGRAQRGQLEPGGEEIVRMSILAS", "length": 797, "header": "tr|A0A8V0YIN0-1|A0A8V0YJE4_CHICK Computationally mapped isoform of Jade family PHD finger 2 OS=Gallus gallus OX=9031 GN=JADE2 PE=3 SV=1 CANONICAL=A0A8V0YJE4-1" }, "locus": { "chromosome": "13", "start_pos": 15414699, "end_pos": 15367212, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031878.1", "url": "https://www.ensembl.org/id/ENSGALT00010031878.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018681.1", "url": "https://www.ensembl.org/id/ENSGALP00010018681.1" } ] } }, { "isoform_ac": "A0A8V0YJE4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJE4/entry#A0A8V0YJE4-1", "sequence": { "sequence": "MLVPSPVLKCARRERRGCKHELFQMEEKRRKYSISSDNSDTTDSHTTSTSRCSKIPSTKSSWSRQKEKKPSEVFRTDLITAMKIPDSFQLSPEEYYVLADPWRQEWEKGVQVPASAEAIPEPVVRIIPQLENLPSPVSPSSLQGSEISEATRTYLQGMSRYDLDELDACWLELVNMELKEMEKPELDEITLERVLEELETMCYENMNIAIETEEGLGIEYDEDVVCDVCRSPEGEDGNEMVFCDKCNVCVHQACYGILKVPIGSWLCRTCALGVQPKCLLCPKRGGALKPTRSGTKWVHVSCALWIPEVSIGCPEKMEPITKISHIPASRWALSCSLCKECTGTCIQCSMPACVTAFHVTCAFDHNLDMRTILADNDEVKFKSFCLEHSTGATKLPEEARTEPDQAQLDLEKVTLRKQKLQQLEEDFYELVKPSEVAENLDLSESLVDFVYQYWKLKRKANSNKPLLTPKTDEVDNLAQQEQDVLYRRLKLFTHLRQDLERVRNLCYMVTRREKMKHTICKLQEQIFHLQMILIEKDLYPEQTGKKTKGKKSDPRRKGRDGRKNSPEKKEKRKSVNETVLGQLGLSTSFPIDGTFFNSWLAQSVQITAENMAMSEWSLNNAHHEDSTPGLSEELLQDEETLLSFMMDHSLRSPFKQSEAAKKVKSKTRTNTKKKPPRSGLTAVFRSQQEGSERWTNHGSDLSDDAAKPCAQESRPGRSEKGAARPADRRGSGEAKRAARRGPGPKGNDPPAPRGCAGEEEAVVAANGARPEPNPAAQVPDPVGSPKTVVRFKLPKESRGTRRSQPPKTDGPGGPPLRRFEAETDGYFSDAEMSDSDGEPRGGRAQRGQLEPGGEEIVRMSILAS", "length": 864, "header": "tr|A0A8V0YJE4-1|A0A8V0YJE4_CHICK Isoform 1 of Jade family PHD finger 2 OS=Gallus gallus OX=9031 GN=JADE2 PE=3 SV=1 CANONICAL=A0A8V0YJE4-1" }, "locus": { "chromosome": "13", "start_pos": 15419926, "end_pos": 15367212, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031881.1", "url": "https://www.ensembl.org/id/ENSGALT00010031881.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018684.1", "url": "https://www.ensembl.org/id/ENSGALP00010018684.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:416315", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416315", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0AAA9SLA8-1", "protein_name": "Jade family PHD finger 2", "gene_name": "JADE2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MHSTGEIAHVGQSCFKEYIAGRLRGAHATTTFGRMEEKRRKYSISSDNSDTTDSHATSASRCSKLPSSTKSGWPRQNEKKPSEVFRTDLITAMKIPDSYQLSPDDYYILADPWRQEWEKGVQVPAGAEAIPEPVVRILPPLEGPPTQVSPSGSELGEGSQPDWAGGSRYDLDEIDAYWLELINSELKEMEKPELDELTLERVLEELETLCHQNMARAIETQEGLGIEYDEDVVCDVCRSPEGEDGNEMVFCDKCNVCVHQACYGILKVPTGSWLCRTCALGVQPKCLLCPKRGGALKPTRSGTKWVHVSCALWIPEVSIGCPEKMEPITKISHIPASRWALSCSLCKECTGTCIQCSMPSCVTAFHVTCAFDHSLEMRTILADNDEVKFKSFCQEHSDGGPRGEAPSEPVEPSPASEDLEKVTLRKQRLQQLEEDFYELVEPAEVAERLDLAEALVDFIYQYWKLKRKANSNQPLLTPKTDEVDNLAQQEQDVLYRRLKLFTHLRQDLERVRNLCYMVTRRERTKHAICKLQEQIFHLQMKLIEQDLCRERSGRKTKGKKSDSKRKGREGPKGSPEKKEKVKAGSDSVLGQLGLSTSFPIDGTFFNSWLAQSVQITAENMAMSEWSLNNGHREDPAPGLLSEELLQDEETLLSFMREPSLRPGDPARKARGRTRLPAKKKPPQDGPGSRTTPDKPPKKPWGQDTGSSKGGQGPPARKPPRRTPSHLPSSPTAGDCPIPAAPESPPPLAPETPEEAAPVAADSNVQVPGPTASPKPLGRLRLPRESKGTRRSPGARPDAGTGPPSAVAERPKVSLHFDTETDGYFSDGEMSDSDVEAEDSGVQPGPREAGAEEVVRMGVLAS", "length": 861 }, "evidence": [ { "id": "A0A8V0YJE4", "url": "https://omabrowser.org/oma/group/A0A8V0YJE4/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0ABK0LGP6-1", "protein_name": "Jade family PHD finger 2", "gene_name": "Jade2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFPDLLISLKGNWDLSRHYHHSVCVCWPPCGPLTPIGRLLFVHVPPRGLLSKKLALWMEEKRRKYSISSDNSDTTDGHVTSTSASRCSKLPSSTKSGWPRQNEKKPSEVFRTDLITAMKIPDSYQLSPDDYYILADPWRQEWEKGVQVPAGAEAIPEPVVRILPPLKGPPTLMSPESPTLGEGAHPDWPGGSRYDLDEIDAYWLELLNSELKEMEKPELDELTLERVLEELETLCHQNMAQAIETQEGLGIEYDEDVVCDVCRSPEGEDGNEMVFCDKCNVCVHQACYGILKVPTGSWLCRTCALGVQPKCLLCPKRGGALKPTRSGTKWVHVSCALWIPEVSIGCPEKMEPITKISHIPASRWALSCSLCKECTGTCIQCSTPSCLTAFHVTCAFDRGLEMRTILADNDEVKFKSLCQEHSDGGPRSEPSSEPVEPSQAVEDLEKVTLRKQRLQQLEENFYELVEPAEVAERLDLAEALVDFIYQYWKLKRRANANQPLLTPKTDEVDNLAQQEQDVLYRRLKLFTHLRQDLERVRNLCYMVTRRERTKHTICKLQEQIFHLQMKLIEQDLCREPSGRRSKGKKNDSKRKGREGPKGSSPEKKEKMKAGPESVLGQLGLSTSFPIDGTFFNSWLAQSVQITAEDMAMSEWSLNSGHREDPAPGLLSEELLQDEETLLSFMRDPSLRPGDPARKARGRTRLPAKKKPPPLQDGPSARTTPEKPAKKAWAQDGKGTQGPPARKPPRRTSSHLPSSPAAGDCPVPATLESPPTLASEILDETVPAASDLNVQVPGPTVSPKPLGRLRPPREMKVSRKSPGARSDAGTGLPSTVAERPKVSLHFDTEADGYFSDEEMSDSDVEAENRGVQRASREAGAEEVVRMGVLAS", "length": 886 }, "evidence": [ { "id": "A0A8V0YJE4", "url": "https://omabrowser.org/oma/group/A0A8V0YJE4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6ZQF7-1", "protein_name": "E3 ubiquitin-protein ligase Jade-2", "gene_name": "Jade2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEEKRRKYSISSDNSDTTDGHVTSTSASRCSKLPSSTKSGWPRQNEKKPSEVFRTDLITAMKIPDSYQLSPDDYYILADPWRQEWEKGVQVPAGAEAIPEPVVRLLPPLKGPPTQMSPDSPTLGEGAHPDWPGGSRYDLDEIDAYWLELLNSELKEMEKPELDELTLERVLEELETLCHQNMAQAIETQEGLGIEYDEDVVCDVCRSPEGEDGNEMVFCDKCNVCVHQACYGILKVPTGSWLCRTCALGVQPKCLLCPKRGGALKPTRSGTKWVHVSCALWIPEVSIGCPEKMEPITKISHIPASRWALSCSLCKECTGTCIQCSMPSCITAFHVTCAFDRGLEMRTILADNDEVKFKSLCQEHSDGGPRSEPTSEPVEPSQAVEDLEKVTLRKQRLQQLEENFYELVEPAEVAERLDLAEALVDFIYQYWKLKRRANANQPLLTPKTDEVDNLAQQEQDVLYRRLKLFTHLRQDLERVRNLCYMVTRRERTKHTICKLQEQIFHLQMKLIEQDLCREPSGRRSKGKKNDSKRKGREGPKGSSPEKKEKVKAGPESVLGQLGLSTSFPIDGTFFNSWLAQSVQITAEDMAMSEWSLNSGHREDPAPGLLSEELLQDEETLLSFMRDPSLRPGDPARKARGRTRLPAKKKPSPLQDGPSARTTPDKQPKKAWAQDGKGTQGPPMRKPPRRTSSHLPSSPAAGDCPVPATLESPPPLASEILDKTAPMASDLNVQVPGPTVSPKPLGRLRPPREMKVSRKSPGARSDAGTGLPSAVAERPKVSLHFDTEADGYFSDEEMSDSEVEAEDSGVQRASREAGAEEVVRMGVLAS", "length": 829 }, "evidence": [ { "id": "A0A8V0YJE4", "url": "https://omabrowser.org/oma/group/A0A8V0YJE4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9NQC1-1", "protein_name": "E3 ubiquitin-protein ligase Jade-2", "gene_name": "JADE2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEEKRRKYSISSDNSDTTDSHATSTSASRCSKLPSSTKSGWPRQNEKKPSEVFRTDLITAMKIPDSYQLSPDDYYILADPWRQEWEKGVQVPAGAEAIPEPVVRILPPLEGPPAQASPSSTMLGEGSQPDWPGGSRYDLDEIDAYWLELINSELKEMERPELDELTLERVLEELETLCHQNMARAIETQEGLGIEYDEDVVCDVCRSPEGEDGNEMVFCDKCNVCVHQACYGILKVPTGSWLCRTCALGVQPKCLLCPKRGGALKPTRSGTKWVHVSCALWIPEVSIGCPEKMEPITKISHIPASRWALSCSLCKECTGTCIQCSMPSCVTAFHVTCAFDHGLEMRTILADNDEVKFKSFCQEHSDGGPRNEPTSEPTEPSQAGEDLEKVTLRKQRLQQLEEDFYELVEPAEVAERLDLAEALVDFIYQYWKLKRKANANQPLLTPKTDEVDNLAQQEQDVLYRRLKLFTHLRQDLERVRNLCYMVTRRERTKHAICKLQEQIFHLQMKLIEQDLCRGLSTSFPIDGTFFNSWLAQSVQITAENMAMSEWPLNNGHREDPAPGLLSEELLQDEETLLSFMRDPSLRPGDPARKARGRTRLPAKKKPPPPPPQDGPGSRTTPDKAPKKTWGQDAGSGKGGQGPPTRKPPRRTSSHLPSSPAAGDCPILATPESPPPLAPETPDEAASVAADSDVQVPGPAASPKPLGRLRPPRESKVTRRLPGARPDAGMGPPSAVAERPKVSLHFDTETDGYFSDGEMSDSDVEAEDGGVQRGPREAGAEEVVRMGVLAS", "length": 790 }, "evidence": [ { "id": "A0A8V0YJE4", "url": "https://omabrowser.org/oma/group/A0A8V0YJE4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJE4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJE4" } ], "pmid": "" }, { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJE4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJE4" } ], "pmid": "" }, { "name": "histone reader activity", "id": "GO:0140566", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140566", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJE4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJE4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJE4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJE4" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJE4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJE4" } ], "pmid": "" }, { "name": "histone acetyltransferase complex", "id": "GO:0000123", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000123", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJE4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJE4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "chromatin remodeling", "id": "GO:0006338", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006338", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJE4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJE4" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJE4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJE4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 576, "end_pos": 578, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YJE4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJE4" }, { "id": "PS50016", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50016" }, { "id": "PS51805", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51805" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PHD-type", "eco_id": "ECO_0000259", "start_pos": 223, "end_pos": 273, "start_aa": "Asp", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 576, "end_pos": 578 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": 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"total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YIN1-1", "uniprot_ac": "A0A8V0YIN1", "uniprot_id": "A0A8V0YIN1_CHICK", "mass": { "chemical_mass": 19943.0, "monoisotopic_mass": 19943.0 }, "refseq": { "ac": "XP_422291", "name": "tRNA-splicing endonuclease subunit Sen15 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_422291" }, "gene_names": [ { "name": "TSEN15", "type": "recommended", "evidence": [ { "id": "A0A8V0YIN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIN1" } ] }, { "name": "TSEN15", "type": "synonym", "evidence": [ { "id": "XP_422291", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_422291" } ] } ], "protein_names": [ { "name": "tRNA splicing endonuclease subunit 15", "type": "synonym", "evidence": [ { "id": "A0A8V0YIN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIN1/entry#names_and_taxonomy" } ] }, { "name": "tRNA-splicing endonuclease subunit Sen15 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_422291", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_422291" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052539.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_422291", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_422291" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIN1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIN1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TSEN15", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIN1", "locus": { "chromosome": "8", "start_pos": 7773711, "end_pos": 7764270, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010011607", "url": "https://www.ensembl.org/id/ENSGALG00010011607" } ] } } ], "crossref": [ { "id": "A0A8V0YIN1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YIN1", "database": "AlphaFoldDB", "categories": [] }, { "id": "424448", "url": "https://www.ncbi.nlm.nih.gov/gene/424448", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011856", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011856", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018593", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018593", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036167", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036167", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:424448", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424448", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "ICHPSYY", "url": "https://omabrowser.org/oma/group/ICHPSYY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YBQ7", "url": "https://www.orthodb.org/?gene=A0A8V0YBQ7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YIN1", "url": "https://www.orthodb.org/?gene=A0A8V0YIN1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR28582", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28582", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR28582:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28582:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF09631", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09631", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_422291", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_422291", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YBQ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBQ7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YBQ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBQ7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YIN1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIN1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YIN1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIN1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEEQAAGRAEEPCGPAEGGSGAERGWAGGGGGDWMATHPTFTAMMSLDISDSSQIYAAFLVYLDLLEGRSWHEVKHVGLAELQLVCLHAREREQGDLQVMVPIPADVLVSHERLREIMKKAALPHDDPDTPLSITLAIVETDSTIVYYKMTDGFVLPEPPDDTEDVDNKQWKRKRRKLSK", "length": 180, "header": "tr|A0A8V0YIN1-1|A0A8V0YIN1_CHICK Isoform 1 of tRNA splicing endonuclease subunit 15 OS=Gallus gallus OX=9031 GN=TSEN15 PE=3 SV=1 CANONICAL=A0A8V0YIN1-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YBQ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIN1/entry#A0A8V0YBQ7-1", "sequence": { "sequence": "MRSLRVNLMRVNTAKCKVLGQSQIRVRTGRTTPCAAGLGFTAMMSLDISDSSQIYAAFLVYLDLLEGRSWHEVKHVGLAELQLVCLHAREREQGDLQVMVPIPADVLVSHERLREIMKKAALPHDDPDTPLSITLAIVETDSTIVYYKMTDGFVLPEPPDDTEDVDNKQWKRKRRKLSK", "length": 179, "header": "tr|A0A8V0YBQ7-1|A0A8V0YBQ7_CHICK Computationally mapped isoform of tRNA splicing endonuclease subunit 15 OS=Gallus gallus OX=9031 GN=TSEN15 PE=3 SV=1 CANONICAL=A0A8V0YIN1-1" }, "locus": { "chromosome": "8", "start_pos": 7773373, "end_pos": 7764321, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027748.1", "url": "https://www.ensembl.org/id/ENSGALT00010027748.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015903.1", "url": "https://www.ensembl.org/id/ENSGALP00010015903.1" } ] } }, { "isoform_ac": "A0A8V0YIN1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIN1/entry#A0A8V0YIN1-1", "sequence": { "sequence": "MEEQAAGRAEEPCGPAEGGSGAERGWAGGGGGDWMATHPTFTAMMSLDISDSSQIYAAFLVYLDLLEGRSWHEVKHVGLAELQLVCLHAREREQGDLQVMVPIPADVLVSHERLREIMKKAALPHDDPDTPLSITLAIVETDSTIVYYKMTDGFVLPEPPDDTEDVDNKQWKRKRRKLSK", "length": 180, "header": "tr|A0A8V0YIN1-1|A0A8V0YIN1_CHICK Isoform 1 of tRNA splicing endonuclease subunit 15 OS=Gallus gallus OX=9031 GN=TSEN15 PE=3 SV=1 CANONICAL=A0A8V0YIN1-1" }, "locus": { "chromosome": "8", "start_pos": 7773373, "end_pos": 7764611, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027746.1", "url": "https://www.ensembl.org/id/ENSGALT00010027746.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015902.1", "url": "https://www.ensembl.org/id/ENSGALP00010015902.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:424448", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424448", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2K1V3-1", "protein_name": "tRNA-splicing endonuclease subunit SEN15", "gene_name": "Tsen15", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEERSDSEPTPGCSGPGPGPVRDGGAAHKWAPEDAWMGTHPKYLEMMELDIGDATQVYIAFLVYLDLMESKSWHEVNCVGIPELQLICLLGTEIEGEGVQTVVPTPISASLSHNRIREILKASRKLQGDPELPMSFTLAIVESDSTIVYYKLTDGFMLPDPQNISLRR", "length": 168 }, "evidence": [ { "id": "A0A8V0YIN1", "url": "https://omabrowser.org/oma/group/A0A8V0YIN1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A3S5ZPS1-1", "protein_name": "tRNA-splicing endonuclease subunit SEN15", "gene_name": "TSEN15", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MEERGESQPTAGCGDVLPGDDRGGGSAHPWAPEDAWMGTHPKYLEMMELDIGDATQVYIAFLVYLDLMESKSWHEVNCVGLPDLQLICLLGTEIEGEGLQTVVPTPISASLSHNRIREILKASRKLQGDPDSPTSFTLAIVESDSTIVYYKLTDGFMLPDPQNISLRR", "length": 168 }, "evidence": [ { "id": "A0A8V0YIN1", "url": "https://omabrowser.org/oma/group/A0A8V0YIN1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q8R3W5-1", "protein_name": "tRNA-splicing endonuclease subunit Sen15", "gene_name": "Tsen15", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEERSDSEPTPGCSGPGPAPVRDGGGAHTWAPEDAWMGTHPKYLEMMELDIGDATQVYIAFLVYLDLMESKSWHEVNCVGIPELQLICLLGTEIEGEGLQTVVPTPISASLSHNRIREILKASRKLQGDPELPMSFTLAIVESDSTIVYYKLTDGFMLPDPQNISLRR", "length": 168 }, "evidence": [ { "id": "A0A8V0YIN1", "url": "https://omabrowser.org/oma/group/A0A8V0YIN1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8WW01-1", "protein_name": "tRNA-splicing endonuclease subunit Sen15", "gene_name": "TSEN15", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEERGDSEPTPGCSGLGPGGVRGFGDGGGAPSWAPEDAWMGTHPKYLEMMELDIGDATQVYVAFLVYLDLMESKSWHEVNCVGLPELQLICLVGTEIEGEGLQTVVPTPITASLSHNRIREILKASRKLQGDPDLPMSFTLAIVESDSTIVYYKLTDGFMLPDPQNISLRR", "length": 171 }, "evidence": [ { "id": "A0A8V0YIN1", "url": "https://omabrowser.org/oma/group/A0A8V0YIN1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIN1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIN1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "nucleic acid binding", "id": "GO:0003676", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003676", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIN1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIN1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "tRNA-type intron splice site recognition and cleavage", "id": "GO:0000379", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000379", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIN1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIN1" } ], "pmid": "" }, { "name": "tRNA splicing, via endonucleolytic cleavage and ligation", "id": "GO:0006388", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006388", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIN1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIN1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YIN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIN1" }, { "id": "PF09631", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09631" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "tRNA-splicing endonuclease subunit Sen15", "eco_id": "ECO_0000259", "start_pos": 60, "end_pos": 159, "start_aa": "Leu", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YIN7-1", "uniprot_ac": "A0A8V0YIN7", "uniprot_id": "A0A8V0YIN7_CHICK", "mass": { "chemical_mass": 92922.0, "monoisotopic_mass": 92922.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "RBP2 ligase", "type": "recommended", "evidence": [ { "id": "A0A8V0YIN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIN7/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIN7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIN7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIN7", "locus": {} } ], "crossref": [ { "id": "A0A8V0YIN7", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YIN7", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR011990", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011990", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019734", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019734", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YIN7", "url": "https://www.orthodb.org/?gene=A0A8V0YIN7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YIN7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIN7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YIN7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIN7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "RSLKGFLFAKLYFEIEEYELAKRYLSIYLSVQERDPKAHRFLGQIYEAQDNIEKAFGCYKRSVELNPVQKDLVLKMAELLCSNDITDGRAKYWVEKAAGLFPGNPAAYRLKEQLLEREGEDGWNQLLDMIQTELCARPDDIYLNIRLVALYRSNNRLRDAVLHCQEAEKKIPVDSSLEWCSCVVKTLEEYLESARDLEPDKNNWRAVKKDHLLAYSSLVKLTLASRDVCESRGALESFDRVLHSVKPYVNGPDELSRTFLEMKGHFYMHAGTFLLKMAQNNEARWRDARELAALCYLKSFYVSPKSKLIEGDASGQDMLEMLACDRKSQSGHMLLNLSHGKADFLKEIVESFANKSGLFTLFESLFGSGASRERSFLGTDDMGDVSTQAPAQGELSKYDIGAVRMHCGSLQHLVWLGLQWNSMSVLFPLRKLLKQLFHLPQETSRLETDAPESICLLDLEVFLLGMVFTCNLQLQEKCTTHDGTHQPPFLPLLLCKQYSTERQRSWWDAVRFFSLEIILETLLVQRGLSTLRAREKHGLQPALMIHWARSLQKAGISLNSRDQKEYTRRSVYYWRKTLLSLKTITKHQSIPEPTDRLFKHFGSVDIQVFEVAAYEEEAHVAIAMLDAVEGKTDDALLSFEAIKNVVAYWNLALCQRKAEELEKDDMLPEEQEERKTYLLKRKHYLMKIIDESSSDPSVADKLPVSVKTVTEMLNAVIQELGENEEKQSLASRNIAQAAHLEVKYSVPSPKKLPFSPTNTYEFSSKTLLQWAEDQKSLLLKLCQQVEALKVNNFCLYIQCRTGDLFVVVSTL", "length": 811, "header": "tr|A0A8V0YIN7-1|A0A8V0YIN7_CHICK Isoform 1 of RBP2 ligase OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0YIN7-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YIN7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIN7/entry#A0A8V0YIN7-1", "sequence": { "sequence": "RSLKGFLFAKLYFEIEEYELAKRYLSIYLSVQERDPKAHRFLGQIYEAQDNIEKAFGCYKRSVELNPVQKDLVLKMAELLCSNDITDGRAKYWVEKAAGLFPGNPAAYRLKEQLLEREGEDGWNQLLDMIQTELCARPDDIYLNIRLVALYRSNNRLRDAVLHCQEAEKKIPVDSSLEWCSCVVKTLEEYLESARDLEPDKNNWRAVKKDHLLAYSSLVKLTLASRDVCESRGALESFDRVLHSVKPYVNGPDELSRTFLEMKGHFYMHAGTFLLKMAQNNEARWRDARELAALCYLKSFYVSPKSKLIEGDASGQDMLEMLACDRKSQSGHMLLNLSHGKADFLKEIVESFANKSGLFTLFESLFGSGASRERSFLGTDDMGDVSTQAPAQGELSKYDIGAVRMHCGSLQHLVWLGLQWNSMSVLFPLRKLLKQLFHLPQETSRLETDAPESICLLDLEVFLLGMVFTCNLQLQEKCTTHDGTHQPPFLPLLLCKQYSTERQRSWWDAVRFFSLEIILETLLVQRGLSTLRAREKHGLQPALMIHWARSLQKAGISLNSRDQKEYTRRSVYYWRKTLLSLKTITKHQSIPEPTDRLFKHFGSVDIQVFEVAAYEEEAHVAIAMLDAVEGKTDDALLSFEAIKNVVAYWNLALCQRKAEELEKDDMLPEEQEERKTYLLKRKHYLMKIIDESSSDPSVADKLPVSVKTVTEMLNAVIQELGENEEKQSLASRNIAQAAHLEVKYSVPSPKKLPFSPTNTYEFSSKTLLQWAEDQKSLLLKLCQQVEALKVNNFCLYIQCRTGDLFVVVSTL", "length": 811, "header": "tr|A0A8V0YIN7-1|A0A8V0YIN7_CHICK Isoform 1 of RBP2 ligase OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0YIN7-1" }, "locus": { "chromosome": "1", "start_pos": 140130533, "end_pos": 140121148, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031537.1", "url": "https://www.ensembl.org/id/ENSGALT00010031537.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018422.1", "url": "https://www.ensembl.org/id/ENSGALP00010018422.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 336, "end_pos": 338, "annotation": "n_glycosylation_sequon" }, { "start_pos": 354, "end_pos": 356, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 336, "end_pos": 338 }, { "start_pos": 354, "end_pos": 356 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YIP1-1", "uniprot_ac": "A0A8V0YIP1", "uniprot_id": "A0A8V0YIP1_CHICK", "mass": { "chemical_mass": 123676.0, "monoisotopic_mass": 123676.0 }, "refseq": { "ac": "XP_004947245", "name": "uncharacterized protein KIAA1755 homolog isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004947245" }, "gene_names": [ { "name": "KIAA1755", "type": "recommended", "evidence": [ { "id": "A0A8V0YIP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIP1" } ] }, { "name": "KIAA1755", "type": "synonym", "evidence": [ { "id": "XP_004947245", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004947245" } ] } ], "protein_names": [ { "name": "KIAA1755", "type": "synonym", "evidence": [ { "id": "A0A8V0YIP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIP1/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein KIAA1755 homolog isoform X1", "type": "synonym", "evidence": [ { "id": "XP_004947245", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004947245" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052551.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_004947245.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004947245", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004947245" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIP1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIP1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "KIAA1755", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIP1", "locus": { "chromosome": "20", "start_pos": 10705335, "end_pos": 10695108, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013266", "url": "https://www.ensembl.org/id/ENSGALG00010013266" } ] } } ], "crossref": [ { "id": "A0A8V0YIP1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YIP1", "database": "AlphaFoldDB", "categories": [] }, { "id": "101750666", "url": "https://www.ncbi.nlm.nih.gov/gene/101750666", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR052231", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052231", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR060650", "url": "https://www.ebi.ac.uk/interpro/entry/IPR060650", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR060651", "url": "https://www.ebi.ac.uk/interpro/entry/IPR060651", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:101750666", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:101750666", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "EMGTEDW", "url": "https://omabrowser.org/oma/group/EMGTEDW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YIP1", "url": "https://www.orthodb.org/?gene=A0A8V0YIP1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45845", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45845", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45845:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45845:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF27628", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF27628", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF27632", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF27632", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_004947245", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004947245", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YIP1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIP1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YIP1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIP1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDSQSLDAAVQSALRALYPPFEATAPAVLGQVFRLLESSYQGDGLCCLLDFLIPAKRLFEHVRRAACAPYSNCIFLHEGWPLCLHEKVVVHLAPLNPLLLRAGDFYLQAEPCQEHAARIALKHLSPDLDSVQETPVPESTYALLFTNEWLEEINCNYAGPPLHTCLVATENGVTPLPWSKIATPEFVDKPKAEPSGTLMGAPGGPGPEPAALTEPMASITPTPHGTAESSVPYSNIAGIAPGCRDSWKPNQGRYPGLIKVEQAGMRQNPTTLAVPSLQEIISQNLGGEYVELLQLSQQDLGLLATSRSVAAQPWVGSWPCRGALSSQDGPCTPCQRRRRLSGEPGPHGPRCRHRDSYLAALQNPVSFGPALMAAILEEPDSSAPLAEPPVQGGSGASTPCSRRARARGSGGQAVGQRSPHLPTAPTRSEAVGSGHKFSFLKGPRLGESAGSQHESGWRKVSAIYSPRMGRAKPAGKGADVAAAAPAEERSPQSTTSQNGPSVPWQELHAGLLHSGIICLPGGTDKLGRALLQVTTSSSAWGAAWCSAAELARLLLCLCSLPRKDAKDSGLTAVVDARKQPPSPTLYSALRSIQNISPGCIHTVLLLAEKEPSAPREKLPGLQVETLTSLKALGRFVDSSQVTAELEGTFPYCHGEWVQFFQRLQPFTASLGRASELLQSCIQELQSTDGAAGMQDAAARIERHQELMRRVLSDPQLVCLQREGGAVLARLRRDAARLRASPHVRAGMDAAEARYAQLEEELHLLVALSNSRLERLSALRKVQELEAELGELTQWLDGEGAARLREMGAEECSPDSCERFTERWSQFLLQAAARHRHGLALCQQADKLQDSVFPEAEPLQAAVALFRTKLMSFQQRMERRQAELEMLHELHRFSGKITCLNAGCRQCSEQTKHGGIPAGRPEALQRLESSFQRLSVEFSTEKLQEMRAQLRRMQSSSGMGAWTAAWHKYQQTRQSLEAMLAELWEGSAASAPCHGAVQASGQPSASSARGRAAGTERRDAARSPAGSPRPRCSSLPTRGGGTPPRPKGNPSQLRSPPRRVSPSPPRAPLCGEPPAHGSAHPRGDAAQYFQVSSHSSFSSEDSDTQNSADETPAAVPAAPQDLGPPGSPKKPSPIVYLENHRAAGLGRADTK", "length": 1150, "header": "tr|A0A8V0YIP1-1|A0A8V0YIP1_CHICK Isoform 1 of KIAA1755 OS=Gallus gallus OX=9031 GN=KIAA1755 PE=4 SV=1 CANONICAL=A0A8V0YIP1-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YIP1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIP1/entry#A0A8V0YIP1-1", "sequence": { "sequence": "MDSQSLDAAVQSALRALYPPFEATAPAVLGQVFRLLESSYQGDGLCCLLDFLIPAKRLFEHVRRAACAPYSNCIFLHEGWPLCLHEKVVVHLAPLNPLLLRAGDFYLQAEPCQEHAARIALKHLSPDLDSVQETPVPESTYALLFTNEWLEEINCNYAGPPLHTCLVATENGVTPLPWSKIATPEFVDKPKAEPSGTLMGAPGGPGPEPAALTEPMASITPTPHGTAESSVPYSNIAGIAPGCRDSWKPNQGRYPGLIKVEQAGMRQNPTTLAVPSLQEIISQNLGGEYVELLQLSQQDLGLLATSRSVAAQPWVGSWPCRGALSSQDGPCTPCQRRRRLSGEPGPHGPRCRHRDSYLAALQNPVSFGPALMAAILEEPDSSAPLAEPPVQGGSGASTPCSRRARARGSGGQAVGQRSPHLPTAPTRSEAVGSGHKFSFLKGPRLGESAGSQHESGWRKVSAIYSPRMGRAKPAGKGADVAAAAPAEERSPQSTTSQNGPSVPWQELHAGLLHSGIICLPGGTDKLGRALLQVTTSSSAWGAAWCSAAELARLLLCLCSLPRKDAKDSGLTAVVDARKQPPSPTLYSALRSIQNISPGCIHTVLLLAEKEPSAPREKLPGLQVETLTSLKALGRFVDSSQVTAELEGTFPYCHGEWVQFFQRLQPFTASLGRASELLQSCIQELQSTDGAAGMQDAAARIERHQELMRRVLSDPQLVCLQREGGAVLARLRRDAARLRASPHVRAGMDAAEARYAQLEEELHLLVALSNSRLERLSALRKVQELEAELGELTQWLDGEGAARLREMGAEECSPDSCERFTERWSQFLLQAAARHRHGLALCQQADKLQDSVFPEAEPLQAAVALFRTKLMSFQQRMERRQAELEMLHELHRFSGKITCLNAGCRQCSEQTKHGGIPAGRPEALQRLESSFQRLSVEFSTEKLQEMRAQLRRMQSSSGMGAWTAAWHKYQQTRQSLEAMLAELWEGSAASAPCHGAVQASGQPSASSARGRAAGTERRDAARSPAGSPRPRCSSLPTRGGGTPPRPKGNPSQLRSPPRRVSPSPPRAPLCGEPPAHGSAHPRGDAAQYFQVSSHSSFSSEDSDTQNSADETPAAVPAAPQDLGPPGSPKKPSPIVYLENHRAAGLGRADTK", "length": 1150, "header": "tr|A0A8V0YIP1-1|A0A8V0YIP1_CHICK Isoform 1 of KIAA1755 OS=Gallus gallus OX=9031 GN=KIAA1755 PE=4 SV=1 CANONICAL=A0A8V0YIP1-1" }, "locus": { "chromosome": "20", "start_pos": 10704331, "end_pos": 10695248, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031889.1", "url": "https://www.ensembl.org/id/ENSGALT00010031889.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018691.1", "url": "https://www.ensembl.org/id/ENSGALP00010018691.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1041, "start_aa": "Thr", "end_pos": 1041, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1041", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:101750666", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:101750666", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "F1MPM8-1", "protein_name": "KIAA1755", "gene_name": "KIAA1755", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MDPPSLDAAIQHALAGLYPPFEATAPTILGQVFRLLDSDFRGDGLNFLLDFLIPAKRLCEQVREAACAPYSHRLFLHEGWPLCLRDEVVVHLAPLNPLLLRQGDFYLQVEPREEQSVCLTIKCLSVDLRTVDAKPVPESSYPLLFTQAWLEAINSDSEGSPLHNCLVASEDGMAPVPWTKITSPEFVDDKPPAVHLLSPAWESLQLEALDLSSSQELHQARCPDRQVLLVQSLGKGRTHRNKYPGLIKVEQAGPGEVGFRVEDLEGEYVALLDFSQESREGSPSKEVAMPSGCPLGTPEELSGTKEIPFSQRMLPLSGANGEPSLEKWACEKPESLGEKPCVWGLGRKANDKVPTQDSEHQPREPYLSIFVNPLHCASGLGTGGSEEPPASKTQGIQGNSENVVQLKPGPKQAPSPRLCPASPLAAPASKTKMEERTKQGNGRLAKPVTKAGRNTSSSGSPTPGLKFSFLKGQRQAPAAPEKASLQHDGPWKVLCSLYSPKPNRAKCLGKAGTTQTETSGLDADSDPVTEEKADFPEASAGPPEKSPALDEDPPGLEPRIGALSVEIFHSRIACLPGGRDRAGRPLLLVSTTKGPWEAPWCTASEVTKLFSYLCTIPRPEDKTKGLAVVIDARKQPPHPGLVSALQATQALVPASIRAMLFLGEKEAALQLEALPDIQVEVLTSLKALSHHVDPSQLPTALEGPFPYCHGEWVQFFQKLDPFLVDLRQASCLLKASIKEFEKGEPPGGVQEASRCLSKSKELMEAVLRDPGLMSLQREGGATLARLRQEGSRLNFNPDVRSHLAEAAALYSLVDEQLHVLATVSNHLLRRLELRVRLGRLEAAIHQVSHWMEQEGSRCLQVLTPKDGSLDTVEKAHAEFEDFFLQAAAQYRRGLELCKQAAQLAAAARAGEAGGTELPELAAFAFTQRAFQAKLTHFYMAAERQRTDLETLLHLHHFCKKVTWFHMDCQDLMAQLRLGKAQRTSPGDQRRLHRYLQRLASEFPAEKLTAMGLQVASLSREGLGRDLWEEAQARHEDIQMLLKKALAHCPCPAGSPAHPTCPELRGAATKDQGLNGEVTSKGRWDLPLQDSLGSDRSPKSRWPPWAPRRGQNRNLQAAPPTQEAGQAVEADEGRTPHGPLDPAPERFLTTLFSWQRLPRQTQISQPAGDSFSSEGTGSQTSLEDSPHTSPPASL", "length": 1193 }, "evidence": [ { "id": "A0A8V0YIP1", "url": "https://omabrowser.org/oma/group/A0A8V0YIP1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1SDX5-1", "protein_name": "KIAA1755", "gene_name": "KIAA1755", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDSPSLDTAIQHALAGLYPPFEATAPTILGQVFRLLDSDFQGDGLSFLLDFLIPAKRLCEQVREAACAPYSHCLFLHEGWPLCLRDEVVVHLAPLNPLLLRQGDFYLQVEPQEEQSVCIMIKCLSVDLRTVDTKPVPMSAYAMLFTQAWLEAINSDFEGGPLHNCLVASEDGVVSVPWTKIASPEFVDDRPQTENVLSPAWGSLQLEALDLSSSQELHQARSPGSQVLLTRSLAKGKSRTRGNKYPGLIKVEPAGPGEVAFRMDDVTSQDLEGDYVALVDFSQESRGGSPIQEVGTSNGYPLGALEELAGTKEIPFCERMLPLSWAKGGSSLEKWACEKPESLEEELCVWGLRRKPNDKVPTQDSEHQPQDPYLHVLVNPLHCVSGLGAGVSEEPAATKTQRLLGNPESMVQLRPKPKQASSPRLRPASPCPAPAPENRMEDRTKQGRGRLPKPVTSPGQNTSSCRSPTSRPKFSFLKGLRQAAVPTEKASLQPDGPWKILCSLYSPKPSRDRCLGKAGTTQTKTSGPDADSDPLTEEKTGFPEASADPPEKSPALDEEPPGLEPRIGALSVEILHSRIASLPGGRDRAGRPLLLVSTSNGLWEAPWCTASEVAKLFSCLCTIPRPEDKTQGLAVVIDARKQPPHPGLVSALQATQALIPTSIGALLFLGEKEAALQLEALPGIQVEVLPSLKALSHHVDPSQLPTALEGPFPYCPSEWVQFFQKLDPFLADLRRASSLLKASIKELEKGDPPGGVQEAARCLSKSKELMEAVLRDPGLLSLQREGGATLAQLQQEGSRLNFNPDVRSHLAEATALYSLVDEQLHVLVTVSNHLLRRLGLRVRLGRLEAAIHQVSNWMEQEGSQYLQVLTPKDGSLETVEKNHAMFEDFFLQAAAQYRRGLELSKQAAQLEAAARGAGEAGGSELPELAAFAFTQRAFQAKLTHFYMAAERQRTDLETLLHLHRFCKKVTWFHMDCQDLMTQLRLGKAQRASPGDQRRLHRYLQRLASEFPAEKLTAMGLQVASLSQEGLGQDLWEEARERHEEIQTLLKKALARCPCPTGPPVLPARLEVREAAAKRQGPNGEVTPEGGRGLPLPDSPGLDRSAKSYWPPWAPRRGQNRNVQAAPPPQEAGQALEADGGKSPHGPLDPAPEGFLTTLFSWQRLPRQSRGPHAAGGSFSSEGTGSLTSLEDSPHTSPPASL", "length": 1201 }, "evidence": [ { "id": "A0A8V0YIP1", "url": "https://omabrowser.org/oma/group/A0A8V0YIP1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q5JYT7-1", "protein_name": "Uncharacterized protein KIAA1755", "gene_name": "KIAA1755", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDPPSLDTAIQHALAGLYPPFEATAPTVLGQVFRLLDSGFQGDGLSFLLDFLIPAKRLCEQVREAACAPYSHCLFLHEGWPLCLRDEVVVHLAPLNPLLLRQGDFYLQVEPQEEQSVCIMIKCLSLDLCTVDKKPVPEPAYPILFTQEWLEAINSDFEGNPLHNCLVASENGIAPVPWTKITSPEFVDDRPQVVNALCQAWGPLPLEALDLSSPQELHQASSPDNQVLPAQSLAKGKGRTYGSKYPGLIKVEQARCGEVAFRMDEVVSQDFEGDYVALLGFSQESRGESPSREAGTSSGCTSGALEEIAGTKETPLFQKILPLSEANEGPSLGNRACTKPESSEERPYNLGFRRKVNLKAPTHNSERPPQGSYMNVLEDALDCASGLRAGVSQEPAASKMQGPLGNPENMVQLRPGPRQASSPRLSPASPAAAASETKIEVKTKERNGRLPKPMPCPSRNTSSPEPPTPGLKFSFLRGQRQPSVTPEKASLQHNGPWKVLCSLYSPKPNRAKSLGKAGTTQTKTSGPATAPSPLTEEKAALPEASAGSPERGPTLEEEPPGPEPRIGALGVKVFRSRIACLPGGRDRAGRPLLLVSTTEGAWEAPWCTVSEVTKLLSYLCTIPRPEDKAKGLAVLIDARRQPPQPGLVSALQATQAQVPASIRAILFLGEKEAALQLQTLPDVQVEVLTSLKALSHHVDPSQLPAVLEGPFPYCHTEWVHFFQKLDPFLADLHQASSLLQASIEEFEKADPPGGMQEATRCLSKSKELMEAVLRDPGLLGLQREGGATLARLQHDASRLDFSPDVRSHLAAATALYSLVDEQLHVLVTASNSLLGKLELRVRLGRLEAAIHQVSDWMEQEGRRCLQSLTPKDGSLETVEKAHAEFENFFLQAAAQYRRGLELSKQAAQLGATARGAGEAERAEFPELAAFASTQRAFQAELTHFYMAAERQRTDLETLLHLHRFCKRMTWFHMDCQDLMAQLRLDKTSRVSPGDQRRLHRYLQRLASEFPAEKLAAVGLQVASLSRAGLGQELWEEARIRHEEIRMLLEKALTHSSCPEAPAAHSARPERRGVAAKGQGVSVEVTSKGRWDQPPLDSLGMDHLPKSYWPPGPPRGEQNRTFQAGSPPQEAGQAAEAEDGKGSHKLPDPAREHLLATTFFRQQPPRQSQVPRLTGGSFSSEGTDSQTSLEDSPQTSPLASL", "length": 1200 }, "evidence": [ { "id": "A0A8V0YIP1", "url": "https://omabrowser.org/oma/group/A0A8V0YIP1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8BWG4-1", "protein_name": "Uncharacterized protein KIAA1755 homolog", "gene_name": "", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDPSALDMAIQHALAGLYPPFEATAPTVLGQVFRLLDSDFRGDGLSFLLDFLIPAKRLCEQVREAACALYTHCLFLHEGWPLCLRDEVVVHLAPLNPLLLRQGDFYLQVESWEEQSVHMTLKCLSSDLREVDKKPIPESSYSLIFTPEWLEAINNDFEGRPLHNCLVASENGITPVPWTKITSPEFVDDRPPIVKVPSSDGDSCPLEDLHLSRPQEPYQAGDLGGKGSVAQIWDKGKGKLSGDKYPGLIKVEPARSGQLAFRTDSEASQSLEGDYVALLGFPQEYRGASPDSEVVTLSVDIQKSQETRPRTKGAPLLGKTLPLSGPAGAPPLGRWACERPAGSGEKPCSGGSRRKARHKASGHTAVRQPQQPHTSVPEKLPDCTSGLVEDTEEEPAASEMQKPVGMPEAMVRLRPGPRQAFSPLLSSAGPGSPAAETKTEETTLGHGRASKPEDCLNKNASFHGSPAPGLQFSFLKEQRVPHVTPEKALLQHARPRKALCPLYSLQPCEAKAPGKDGTTLPTTSGSGPLSGEPPGFRRDSAGPPGGGLRLEECSRTKPRIETLGVKLLQSGIACLPGGRDKVGRPLLLVSTAEDAWEAPWCTTSEVAELLSYLCSVPRLEDKAKGLLVVIDARKGTQRPGLVSALQGIQALAPASVSKVLLLGEKASIPQLSVLPAQVEVLTSLKALRNHVDPSQLPEALEGPFPYHHSEWVQFFQKLDPFLTDLRQASSLLQASIQEFEKGEPPGGVQEATRCLSKSKELMETVLRDPGLLALQREGGTTLASLQQEASGLNANPDVRSHLTEAAALYNLVDGQLHDLVTASNQLLRRLELRVRLGHLETAIHQVSDWMAGEGSQSLQALAPVHVCAETVEKVHAEFEDFFLQVAAQYRQGLDLSKQAAQLGAAEEGAGEMGLPDLAAFASTQQAFQARLTHFYMAAERQRTDLETLLHLHRFRRKMSRFHMDCQNLLTQLSLGKAVKASPGDQLHLRLHCYLKRLASEFQTEKLLAMKLQVASLSRPGLGQEVWEEAQERHQEIQSLLRKALAYCPCPEVPATQVALIDRSRPVAKGQGLPREVGSKWDRSLQDSLAVDHVFKSQRTPQGEQSRNMWAGLLSPEPGQSGDTEEVRGTPKLPDPTLERLLASLFSWPHLPKQSKASRPTGGSFSSEGTGSQTSLEDSPHTSPPASL", "length": 1187 }, "evidence": [ { "id": "A0A8V0YIP1", "url": "https://omabrowser.org/oma/group/A0A8V0YIP1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9WVJ6-1", "protein_name": "Protein-glutamine gamma-glutamyltransferase 2", "gene_name": "Tgm2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAEELNLERCDLEIQANGRDHHTADLCQQKLVLRRGQRFRLTLYFEGRGYEASVDRLTFGAVTGPDPSEEAGTKARFSLSDDVEEGSWSASVLDQQDNVLSLQLCTPANAPVGQYRLSLETSTGYQGSSFMLGHFILLFNAWCPADDVYLDSEAERREYVLTQQGFIYQGSVKFIKSVPWNFGQFEDGILDACLMLLDVNPKFLKDRSRDCSRRSSPIYVGRVVSGMVNCNDDQGVLLGRWDNNYGDGISPMAWIGSVDILRRWKEHGCQQVKYGQCWVFAAVACTVLRCLGIPTRVVTNYNSAHDQNSNLLIEYFRNEYGELESNKSEMIWNFHCWVESWMTRPDLQPGYEGWQAIDPTPQEKSEGTYCCGPVSVRAIKEGDLSTKYDASFVFAEVNADVVDWIRQSDGSVLKSINNSLVVGQKISTKSVGRDDREDITYTYKYPEGSPEEREVFTRANHLNKLAEKEETGVAMRIRVGDGMSLGNDFDVFAHIGNDTSESRECRLLLCARTVSYNGVLGPECGTEDINLTLDPYSENSIPLRILYEKYSGCLTESNLIKVRGLLVEPAANSYLLAERDLYLENPEIKIRILGEPKQNRKLVAEVSLKNPLSDSLYDCVFTVEGAGLTKEQKSVEVSDPVPAGDAVKVRVDLFPTDIGLHKLVVNFQCDKLKSVKGYRNIIIGPA", "length": 686 }, "evidence": [ { "id": "A0A8V0YIP1", "url": "https://omabrowser.org/oma/group/A0A8V0YIP1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 594, "end_pos": 596, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YIP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIP1" }, { "id": "PF27632", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF27632" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Rho guanine nucleotide exchange factor 40-like C-terminal", "eco_id": "ECO_0000259", "start_pos": 924, "end_pos": 980, "start_aa": "Gln", "end_aa": "Ala", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0YIP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIP1" }, { "id": "PF27628", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF27628" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Rho guanine nucleotide exchange factor 40-like N-terminal", "eco_id": "ECO_0000259", "start_pos": 4, "end_pos": 182, "start_aa": "Gln", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 1041 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 594, "end_pos": 596 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { 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"MRENSTVTYPRVRAPPGPPAPVPAPPRYSAPPRHCEMADAGSLFCFLMASCAAFALSSLAAAVPRLRTRRTAGPGGAAGPGTGDGMNVLFIVVDDLRPVLGCYGDNLVKSPNIDQLASQSIVFSNAYAQQAVCAPSRVSFLTGRRPDTTRLYDFYSYWRVHSGNYSTMPQYFKENGYVTMSVGKVFHPGISSNYSDDYPYSWSIPPFHPSTEKYENDKTCRGKDGRLYANLVCPIDVTEMPGGTLPDIETTEEAIRLLNVMKTKKQKFFLAVGYHKPHIPLRYPQEFLKLYPLENITLAPDPWVPEKLPPVAYNPWVDIRQRDDVKALNVTFPYGPLPDDFQRLIRQSYYAAVSYLDMQVGLLLNALDYVGLSNSTIVVFTADHGWSLGEHGEWAKYSNFDVATQVPLMFYVPRMTTSSASQGERVFPYLDPFSHIVGLVPQGQRKKMVELVSLFSTLAELAGLQVPPACPETSFHVALCTEGASIVRYFKSSEQKVQKKENGCNDTNKYYSEEPVAFSQYPRPADTPQWDSDKPKLKDIRIMGYSMRTIDYRYTVWVQFNPENFSADFEDVHAGELYMMETDPNQDNNIYNNTLHGHLFKKIVDFLKH", "length": 609, "header": "tr|A0A8V0YIQ1-1|A0A8V0YIQ1_CHICK Isoform 1 of Iduronate 2-sulfatase OS=Gallus gallus OX=9031 GN=IDS PE=3 SV=1 CANONICAL=A0A8V0YIQ1-1" }, "isoforms": [ { "isoform_ac": "A0A1L1RU31-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIQ1/entry#A0A1L1RU31-1", "sequence": { "sequence": "MNVLFIVVDDLRPVLGCYGDNLVKSPNIDQLASQSIVFSNAYAQQAVCAPSRVSFLTGRRPDTTRLYDFYSYWRVHSGNYSTMPQYFKENGYVTMSVGKVFHPGISSNYSDDYPYSWSIPPFHPSTEKYENDKTCRGKDGRLYANLVCPIDVTEMPGGTLPDIETTEEAIRLLNVMKTKKQKFFLAVGYHKPHIPLRYPQEFLKLYPLENITLAPDPWVPEKLPPVAYNPWVDIRQRDDVKALNVTFPYGPLPDDFQRLIRQSYYAAVSYLDMQVGLLLNALDYVGLSNSTIVVFTADHGWSLGEHGEWAKYSNFDVATQVPLMFYVPRMTTSSASQGERVFPYLDPFSHIVGLVPQGQRKKMVELVSLFSTLAELAGLQVPPACPETSFHVALCTEGASIVRYFKSSEQKVQKKENGCNDTNKYYSEEPVAFSQYPRPADTPQWDSDKPKLKDIRIMGYSMRTIDYRYTVWVQFNPENFSADFEDVHAGELYMMETDPNQDNNIYNNTLHGHLFKKIVDFLKH", "length": 524, "header": "tr|A0A1L1RU31-1|A0A1L1RU31_CHICK Computationally mapped isoform of Iduronate 2-sulfatase OS=Gallus gallus OX=9031 GN=IDS PE=3 SV=2 CANONICAL=A0A8V0YIQ1-1" }, "locus": { "chromosome": "4", "start_pos": 18040791, "end_pos": 18033540, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031567.1", "url": "https://www.ensembl.org/id/ENSGALT00010031567.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018443.1", "url": "https://www.ensembl.org/id/ENSGALP00010018443.1" } ] } }, { "isoform_ac": "A0A8V0YCB4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIQ1/entry#A0A8V0YCB4-1", "sequence": { "sequence": "MADAGSLFCFLMASCAAFALSSLAAAVPRLRTRRTAGPGDGMNVLFIVVDDLRPVLGCYGDNLVKSPNIDQLASQSIVFSNAYAQQAVCAPSRVSFLTGRRPDTTRLYDFYSYWRVHSGNYSTMPQYFKENGYVTMSVGKVFHPGISSNYSDDYPYSWSIPPFHPSTEKYENDKTCRGKDGRLYANLVCPIDVTEMPGGTLPDIETTEEAIRLLNVMKTKKQKFFLAVGYHKPHIPLRYPQEFLKLYPLENITLAPDPWVPEKLPPVAYNPWVDIRQRDDVKALNVTFPYGPLPDDFQRLIRQSYYAAVSYLDMQVGLLLNALDYVGLSNSTIVVFTADHGWSLGEHGEWAKYSNFDVATQVPLMFYVPRMTTSSASQGERVFPYLDPFSHIVGLVPQGNKMMKEMFYDWTQTSTMVSYTLAVDVCTNTAGQRKKMVELVSLFSTLAELAGLQVPPACPETSFHVALCTEGASIVRYFKSSEQKVQKKENGCNDTNKYYSEEPVAFSQYPRPADTPQWDSDKPKLKDIRIMGYSMRTIDYRYTVWVQFNPENFSADFEDVHAGELYMMETDPNQDNNIYNNTLHGHLFKKIVDFLKH", "length": 597, "header": "tr|A0A8V0YCB4-1|A0A8V0YCB4_CHICK Computationally mapped isoform of Iduronate 2-sulfatase OS=Gallus gallus OX=9031 GN=IDS PE=3 SV=1 CANONICAL=A0A8V0YIQ1-1" }, "locus": { "chromosome": "4", "start_pos": 18040791, "end_pos": 18026252, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031559.1", "url": "https://www.ensembl.org/id/ENSGALT00010031559.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018435.1", "url": "https://www.ensembl.org/id/ENSGALP00010018435.1" } ] } }, { "isoform_ac": "A0A8V0YCB7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIQ1/entry#A0A8V0YCB7-1", "sequence": { "sequence": "MRENSTVTYPRVRAPPGPPAPVPAPPRYSAPPRHCEMADAGSLFCFLMASCAAFALSSLAAAVPRLRTRRTAGPGDGMNVLFIVVDDLRPVLGCYGDNLVKSPNIDQLASQSIVFSNAYAQQAVCAPSRVSFLTGRRPDTTRLYDFYSYWRVHSGNYSTMPQYFKENGYVTMSVGKVFHPGISSNYSDDYPYSWSIPPFHPSTEKYENDKTCRGKDGRLYANLVCPIDVTEMPGGTLPDIETTEEAIRLLNVMKTKKQKFFLAVGYHKPHIPLRYPQEFLKLYPLENITLAPDPWVPEKLPPVAYNPWVDIRQRDDVKALNVTFPYGPLPDDFQRLIRQSYYAAVSYLDMQVGLLLNALDYVGLSNSTIVVFTADHGWSLGEHGEWAKYSNFDVATQVPLMFYVPRMTTSSASQGERVFPYLDPFSHIVGLVPQGQRKKMVELVSLFSTLAELAGLQVPPACPETSFHVALCTEGASIVRYFKSSEQKVQKKENGCNDTNKYYSEEPVAFSQYPRPADTPQWDSDKPKLKDIRIMGYSMRTIDYRYTVWVQFNPENFSADFEDVHAGELYMMETDPNQDNNIYNNTLHGHLFKKIVDFLKH", "length": 601, "header": "tr|A0A8V0YCB7-1|A0A8V0YCB7_CHICK Computationally mapped isoform of Iduronate 2-sulfatase OS=Gallus gallus OX=9031 GN=IDS PE=3 SV=1 CANONICAL=A0A8V0YIQ1-1" }, "locus": { "chromosome": "4", "start_pos": 18040791, "end_pos": 18026144, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031564.1", "url": "https://www.ensembl.org/id/ENSGALT00010031564.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018440.1", "url": "https://www.ensembl.org/id/ENSGALP00010018440.1" } ] } }, { "isoform_ac": "A0A8V0YIQ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIQ1/entry#A0A8V0YIQ1-1", "sequence": { "sequence": "MRENSTVTYPRVRAPPGPPAPVPAPPRYSAPPRHCEMADAGSLFCFLMASCAAFALSSLAAAVPRLRTRRTAGPGGAAGPGTGDGMNVLFIVVDDLRPVLGCYGDNLVKSPNIDQLASQSIVFSNAYAQQAVCAPSRVSFLTGRRPDTTRLYDFYSYWRVHSGNYSTMPQYFKENGYVTMSVGKVFHPGISSNYSDDYPYSWSIPPFHPSTEKYENDKTCRGKDGRLYANLVCPIDVTEMPGGTLPDIETTEEAIRLLNVMKTKKQKFFLAVGYHKPHIPLRYPQEFLKLYPLENITLAPDPWVPEKLPPVAYNPWVDIRQRDDVKALNVTFPYGPLPDDFQRLIRQSYYAAVSYLDMQVGLLLNALDYVGLSNSTIVVFTADHGWSLGEHGEWAKYSNFDVATQVPLMFYVPRMTTSSASQGERVFPYLDPFSHIVGLVPQGQRKKMVELVSLFSTLAELAGLQVPPACPETSFHVALCTEGASIVRYFKSSEQKVQKKENGCNDTNKYYSEEPVAFSQYPRPADTPQWDSDKPKLKDIRIMGYSMRTIDYRYTVWVQFNPENFSADFEDVHAGELYMMETDPNQDNNIYNNTLHGHLFKKIVDFLKH", "length": 609, "header": "tr|A0A8V0YIQ1-1|A0A8V0YIQ1_CHICK Isoform 1 of Iduronate 2-sulfatase OS=Gallus gallus OX=9031 GN=IDS PE=3 SV=1 CANONICAL=A0A8V0YIQ1-1" }, "locus": { "chromosome": "4", "start_pos": 18040791, "end_pos": 18026144, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031561.1", "url": "https://www.ensembl.org/id/ENSGALT00010031561.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018437.1", "url": "https://www.ensembl.org/id/ENSGALP00010018437.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "R-GGA-2024096", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2024096", "resource": "Reactome", "description": "HS-GAG degradation" }, { "id": "R-GGA-2024101", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2024101", "resource": "Reactome", "description": "CS/DS degradation" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "iduronate-2-sulfatase activity", "id": "GO:0004423", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004423", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIQ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIQ1" } ], "pmid": "" }, { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIQ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIQ1" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIQ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIQ1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "dermatan sulfate proteoglycan catabolic process", "id": "GO:0030209", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030209", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIQ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIQ1" } ], "pmid": "" }, { "name": "glycosaminoglycan catabolic process", "id": "GO:0006027", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006027", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIQ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIQ1" } ], "pmid": "" }, { "name": "heparan sulfate proteoglycan catabolic process", "id": "GO:0030200", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030200", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIQ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIQ1" } ], "pmid": "" }, { "name": "carbohydrate derivative catabolic process", "id": "GO:1901136", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901136", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIQ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIQ1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "lysosome", "id": "GO:0005764", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005764", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIQ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIQ1" } ], "pmid": "" }, { "name": "lysosomal lumen", "id": "GO:0043202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043202", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIQ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIQ1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 164, "end_pos": 166, "annotation": "n_glycosylation_sequon" }, { "start_pos": 193, "end_pos": 195, "annotation": "n_glycosylation_sequon" }, { "start_pos": 295, "end_pos": 297, "annotation": "n_glycosylation_sequon" }, { "start_pos": 329, "end_pos": 331, "annotation": "n_glycosylation_sequon" }, { "start_pos": 374, "end_pos": 376, "annotation": "n_glycosylation_sequon" }, { "start_pos": 4, "end_pos": 6, "annotation": "n_glycosylation_sequon" }, { "start_pos": 505, "end_pos": 507, "annotation": "n_glycosylation_sequon" }, { "start_pos": 564, "end_pos": 566, "annotation": "n_glycosylation_sequon" }, { "start_pos": 592, "end_pos": 594, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-GGA-1678650", "name": "IDS hydrolyses Heparan sulfate chain(5)", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "lysosomal lumen", "input_participant_list": [ "R-ALL-2090080" ], "output_participant_list": [], "enzyme_list": [ "A0A8V0YIQ1-1" ], "evidence": [ { "id": "R-GGA-1678650", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1678650" } ] }, { "id": "R-GGA-1793182", "name": "IDS hydrolyses dermatan sulfate (Chebi:63517 chain)", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "lysosomal lumen", "input_participant_list": [ "R-ALL-2065213" ], "output_participant_list": [], "enzyme_list": [ "A0A8V0YIQ1-1" ], "evidence": [ { "id": "R-GGA-1793182", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1793182" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-2065213", "participant_name": "ChEBI:63517 chain [lysosomal lumen]", "crossref": [ { "id": "747397", "database": "ChEBI", "url": "" } ] }, { "participant_id": "R-ALL-2090080", "participant_name": "IdoA2S-GlcNS3S- group [lysosomal lumen]", "crossref": [ { "id": "63808", "database": "ChEBI", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A0A8V0YIQ1", "gene_name": "IDS", "activity": [ { "ec_number": "3.1.6.13", "activity": "Hydrolysis of the 2-sulfate groups of the L-iduronate 2-sulfate units of dermatan sulfate, heparan sulfate and heparin.", "evidence": [ { "id": "A0A8V0YIQ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIQ1" } ] }, { "ec_number": "3.1.6.13", "activity": "", "evidence": [ { "id": "A0A8V0YIQ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIQ1" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YIQ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIQ1" }, { "id": "PF00884", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00884" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Sulfatase N-terminal", "eco_id": "ECO_0000259", "start_pos": 87, "end_pos": 463, "start_aa": "Asn", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "3.1.6.13", "ec_name": "Hydrolysis of the 2-sulfate groups of the L-iduronate 2-sulfate units of dermatan sulfate, heparan sulfate and heparin.", "evidence": [ { "id": "3.1.6.13", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=3.1.6.13" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 164, "end_pos": 166 }, { "start_pos": 193, "end_pos": 195 }, { "start_pos": 295, "end_pos": 297 }, { "start_pos": 329, "end_pos": 331 }, { "start_pos": 374, "end_pos": 376 }, { "start_pos": 4, "end_pos": 6 }, { "start_pos": 505, "end_pos": 507 }, { "start_pos": 564, "end_pos": 566 }, { "start_pos": 592, "end_pos": 594 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": 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"n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YIQ5-1", "uniprot_ac": "A0A8V0YIQ5", "uniprot_id": "A0A8V0YIQ5_CHICK", "mass": { "chemical_mass": 43114.0, "monoisotopic_mass": 43114.0 }, "refseq": { "ac": "XP_015137679", "name": "leukocyte elastase inhibitor isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015137679" }, "gene_names": [ { "name": "SERPINB1", "type": "recommended", "evidence": [ { "id": "A0A8V0YIQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIQ5" } ] }, { "name": "SERPINB1", "type": "synonym", "evidence": [ { "id": "XP_015137679", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015137679" } ] } ], "protein_names": [ { "name": "Serpin family B member 1", "type": "synonym", "evidence": [ { "id": "A0A8V0YIQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIQ5/entry#names_and_taxonomy" } ] }, { "name": "leukocyte elastase inhibitor isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015137679", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015137679" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052533.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015137679.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015137679", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015137679" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIQ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIQ5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SERPINB1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIQ5", "locus": { "chromosome": "2", "start_pos": 67364149, "end_pos": 67372288, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010011626", "url": "https://www.ensembl.org/id/ENSGALG00010011626" } ] } } ], "crossref": [ { "id": "A0A8V0YIQ5", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YIQ5", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd19560", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd19560", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "420894", "url": "https://www.ncbi.nlm.nih.gov/gene/420894", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000215", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000215", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023795", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023795", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023796", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023796", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036186", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036186", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042178", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042178", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042185", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042185", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:420894", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420894", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YFNAAWA", "url": "https://omabrowser.org/oma/group/YFNAAWA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y5L4", "url": "https://www.orthodb.org/?gene=A0A8V0Y5L4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YIQ5", "url": "https://www.orthodb.org/?gene=A0A8V0YIQ5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11461", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11461", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11461:SF180", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11461:SF180", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00079", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00079", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-6798695", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6798695", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_015137679", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015137679", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Y5L4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5L4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y5L4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5L4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YIQ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIQ5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YIQ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIQ5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MESLSNANSRFALDLFRKVNETNPSGNIFFSPLSISTALAMVLLGSRGNTETQVLKTFHFDEVENIHSRFRALTADINRRDSSCLLRIANRLYGEKSYSFLPEFLTNTQKSYGADLAAVDFLHAYGEARKEINQWVEEKTEGKIPDLLSEGSVNSMTKLVLVNAIYFKGNWAEKFEEANTADMPFRLNKNERKTVKMMYQKKKFRFGYISDMKTRVLELPYDEREFSMIILLPDDIEDDSTGLQKLEQQLTLEKLQEWTRPEHLYSTDVHVHLPKFKLEESYDLKSDLSAMGLLDIFDSAKADLSGMSGAHDLFLSKIVHKAFVEVNEEGTEAAAATAGIAMLCMVIEEDFNADHPFLFFLRHNPTKSIVFFGRYASP", "length": 378, "header": "tr|A0A8V0YIQ5-1|A0A8V0YIQ5_CHICK Isoform 1 of Serpin family B member 1 OS=Gallus gallus OX=9031 GN=SERPINB1 PE=1 SV=1 CANONICAL=A0A8V0YIQ5-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Y5L4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIQ5/entry#A0A8V0Y5L4-1", "sequence": { "sequence": "MESLSNANSSISTALAMVLLGSRGNTETQVLKTFHFDEVENIHSRFRALTADINRRDSSCLLRIANRLYGEKSYSFLPEFLTNTQKSYGADLAAVDFLHAYGEARKEINQWVEEKTEGKIPDLLSEGSVNSMTKLVLVNAIYFKGNWAEKFEEANTADMPFRLNKNERKTVKMMYQKKKFRFGYISDMKTRVLELPYDEREFSMIILLPDDIEDDSTGLQKLEQQLTLEKLQEWTRPEHLYSTDVHVHLPKFKLEESYDLKSDLSAMGLLDIFDSAKADLSGMSGAHDLFLSKIVHKAFVEVNEEGTEAAAATAGIAMLCMVIEEDFNADHPFLFFLRHNPTKSIVFFGRYASP", "length": 354, "header": "tr|A0A8V0Y5L4-1|A0A8V0Y5L4_CHICK Computationally mapped isoform of Serpin family B member 1 OS=Gallus gallus OX=9031 GN=SERPINB1 PE=1 SV=1 CANONICAL=A0A8V0YIQ5-1" }, "locus": { "chromosome": "2", "start_pos": 67371851, "end_pos": 67365335, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027784.1", "url": "https://www.ensembl.org/id/ENSGALT00010027784.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015926.1", "url": "https://www.ensembl.org/id/ENSGALP00010015926.1" } ] } }, { "isoform_ac": "A0A8V0YIQ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIQ5/entry#A0A8V0YIQ5-1", "sequence": { "sequence": "MESLSNANSRFALDLFRKVNETNPSGNIFFSPLSISTALAMVLLGSRGNTETQVLKTFHFDEVENIHSRFRALTADINRRDSSCLLRIANRLYGEKSYSFLPEFLTNTQKSYGADLAAVDFLHAYGEARKEINQWVEEKTEGKIPDLLSEGSVNSMTKLVLVNAIYFKGNWAEKFEEANTADMPFRLNKNERKTVKMMYQKKKFRFGYISDMKTRVLELPYDEREFSMIILLPDDIEDDSTGLQKLEQQLTLEKLQEWTRPEHLYSTDVHVHLPKFKLEESYDLKSDLSAMGLLDIFDSAKADLSGMSGAHDLFLSKIVHKAFVEVNEEGTEAAAATAGIAMLCMVIEEDFNADHPFLFFLRHNPTKSIVFFGRYASP", "length": 378, "header": "tr|A0A8V0YIQ5-1|A0A8V0YIQ5_CHICK Isoform 1 of Serpin family B member 1 OS=Gallus gallus OX=9031 GN=SERPINB1 PE=1 SV=1 CANONICAL=A0A8V0YIQ5-1" }, "locus": { "chromosome": "2", "start_pos": 67371851, "end_pos": 67365335, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027785.1", "url": "https://www.ensembl.org/id/ENSGALT00010027785.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015927.1", "url": "https://www.ensembl.org/id/ENSGALP00010015927.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:420894", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420894", "resource": "KEGG Pathway" }, { "id": "R-GGA-6798695", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6798695", "resource": "Reactome", "description": "Neutrophil degranulation" } ], "orthologs": [ { "uniprot_canonical_ac": "G3GWX6-1", "protein_name": "Leukocyte elastase inhibitor", "gene_name": "Serpinb1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MEQLSTANNLFALELFRSLNENNSTGNIFISPFSISSALAMVFLGTRGNTAAQLSKTFHFDAVEDVHSRFQSLNAEVGKRGASHILKLANRLYGEKTYNFLPEFLDSTQKMYGADLAQVDFQHASEDARKAINQWVKGQTEGKIPELLAEGVVDSMTKLVLVNAIYFKGMWREKFRKKDTTDAPFRLNKKDTKTVKMMYQKEKFPFGYIRDLKCKVLEMPYQGEELSMVILLPEDIEDESTGLKKIEEQLTLEKLREWTKHENLENIDVHVKLPRFKLEESYTLNSNLGSLGVQDLFSSSKADLSGMSGSRDLFISKIIHKSFVEVNEEGTEAAAATGGIATFAMLMPEEEFTVDHPFIFFIRHNPTANVLFLGRVCSP", "length": 379 }, "evidence": [ { "id": "A0A8V0YIQ5", "url": "https://omabrowser.org/oma/group/A0A8V0YIQ5/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P30740-1", "protein_name": "Leukocyte elastase inhibitor", "gene_name": "SERPINB1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEQLSSANTRFALDLFLALSENNPAGNIFISPFSISSAMAMVFLGTRGNTAAQLSKTFHFNTVEEVHSRFQSLNADINKRGASYILKLANRLYGEKTYNFLPEFLVSTQKTYGADLASVDFQHASEDARKTINQWVKGQTEGKIPELLASGMVDNMTKLVLVNAIYFKGNWKDKFMKEATTNAPFRLNKKDRKTVKMMYQKKKFAYGYIEDLKCRVLELPYQGEELSMVILLPDDIEDESTGLKKIEEQLTLEKLHEWTKPENLDFIEVNVSLPRFKLEESYTLNSDLARLGVQDLFNSSKADLSGMSGARDIFISKIVHKSFVEVNEEGTEAAAATAGIATFCMLMPEENFTADHPFLFFIRHNSSGSILFLGRFSSP", "length": 379 }, "evidence": [ { "id": "A0A8V0YIQ5", "url": "https://omabrowser.org/oma/group/A0A8V0YIQ5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q1JPB0-1", "protein_name": "Leukocyte elastase inhibitor", "gene_name": "SERPINB1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MEQLSAANTRFAVDLFLTLTEHNPAGNIFISPFSISSALAMVFLGARGDTAAQMSKALHFEGVEIHSGFQSLNADINKCGAPYTLKLANRLFGEKSYDFLPEFLASTQEMYSAELASVDFLRAPEDARKTINAWVKEQTGGKIPELLASGMVDSLTKLVLVNAIYFKGKWQEKFMVEATKDAPFRLNKKETKTVKMMYQKKKFPFGYIKDLKCRVLELPYEGKDLSMVILLPDDIQDEATGLKKIEQQLTLEKLREWTRPESLDLLEVRVQLPRFKLEESYDLQEPLARLGVRDLFSSKADLSGMSGAKDLFISKVVHKSVVDVNEEGTEAAAATGAIAEFAMLVPEEEFVADHPFIFFIRHKPSSNILFLGRLSSP", "length": 377 }, "evidence": [ { "id": "A0A8V0YIQ5", "url": "https://omabrowser.org/oma/group/A0A8V0YIQ5/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q4G075-1", "protein_name": "Leukocyte elastase inhibitor A", "gene_name": "Serpinb1a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEQLSSANSLFALELFHTLSESSPTGNIFFSPFSISSALAMVFLGTKGTTAAQLSKTFHFDSVEDVHSRFQSLNAEVSKRGASHTLKLANRLYGEKTYNFLPEFLTSTQKMYGADLAPVDFQHASEDARKEINQWVKGQTEGKIPELLAVGVVDSMTKLVLVNAIYFKGMWEEKFMKQDTTDAPFRLNKKNTKSVKMMYQKKKFFFGYISDLKCKVLEMPYQGGELSMVILLPEDIEDESTGLKKIEEQITLEKLREWTKRENLENIDVHVKLPRFKIEESYILNSNLGRLGLQDLFNSSKADLSGMSGSRDLFISKIVHKAFVEVNEEGTEAAAATAGIATFCMLLPEEEFTADHPFIFFIRHNPTANVLFLGRVCSP", "length": 379 }, "evidence": [ { "id": "A0A8V0YIQ5", "url": "https://omabrowser.org/oma/group/A0A8V0YIQ5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9D154-1", "protein_name": "Leukocyte elastase inhibitor A", "gene_name": "Serpinb1a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEQLSSANTLFALELFQTLNESSPTGNIFFSPFSISSALAMVILGAKGSTAAQLSKTFHFDSVEDIHSRFQSLNAEVSKRGASHTLKLANRLYGEKTYNFLPEYLASTQKMYGADLAPVDFLHASEDARKEINQWVKGQTEGKIPELLSVGVVDSMTKLVLVNAIYFKGMWEEKFMTEDTTDAPFRLSKKDTKTVKMMYQKKKFPFGYISDLKCKVLEMPYQGGELSMVILLPKDIEDESTGLKKIEKQITLEKLLEWTKRENLEFIDVHVKLPRFKIEESYTLNSNLGRLGVQDLFSSSKADLSGMSGSRDLFISKIVHKSFVEVNEEGTEAAAATGGIATFCMLLPEEEFTVDHPFIFFIRHNPTSNVLFLGRVCSP", "length": 379 }, "evidence": [ { "id": "A0A8V0YIQ5", "url": "https://omabrowser.org/oma/group/A0A8V0YIQ5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "serine-type endopeptidase inhibitor activity", "id": "GO:0004867", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004867", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIQ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIQ5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIQ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIQ5" } ], "pmid": "" }, { "name": "cytoplasmic ribonucleoprotein granule", "id": "GO:0036464", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036464", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIQ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIQ5" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIQ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIQ5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "negative regulation of cell migration", "id": "GO:0030336", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030336", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIQ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIQ5" } ], "pmid": "" }, { "name": "negative regulation of interleukin-1 beta production", "id": "GO:0032691", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032691", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIQ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIQ5" } ], "pmid": "" }, { "name": "type B pancreatic cell proliferation", "id": "GO:0044342", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044342", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIQ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIQ5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 20, "end_pos": 22, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YIQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIQ5" }, { "id": "SM00093", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00093" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Serpin", "eco_id": "ECO_0000259", "start_pos": 13, "end_pos": 378, "start_aa": "Leu", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 20, "end_pos": 22 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YIR5-1", "uniprot_ac": "A0A8V0YIR5", "uniprot_id": "A0A8V0YIR5_CHICK", "mass": { "chemical_mass": 114280.0, "monoisotopic_mass": 114280.0 }, "refseq": { "ac": "NP_001383172", "name": "beta-alanine-activating enzyme isoform 2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001383172" }, "gene_names": [ { "name": "AASDH", "type": "recommended", "evidence": [ { "id": "A0A8V0YIR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIR5" } ] }, { "name": "AASDH", "type": "synonym", "evidence": [ { "id": "NP_001383172", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001383172" } ] } ], "protein_names": [ { "name": "Aminoadipate-semialdehyde dehydrogenase", "type": "synonym", "evidence": [ { "id": "A0A8V0YIR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIR5/entry#names_and_taxonomy" } ] }, { "name": "beta-alanine-activating enzyme isoform 2", "type": "synonym", "evidence": [ { "id": "NP_001383172", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001383172" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: SRR13267649.228681.1, SRR13267655.201561.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000074.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001383172", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001383172" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIR5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIR5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "AASDH", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIR5", "locus": { "chromosome": "4", "start_pos": 64327346, "end_pos": 64305487, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010014902", "url": "https://www.ensembl.org/id/ENSGALG00010014902" } ] } } ], "crossref": [ { "id": "A0A8V0YIR5", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YIR5", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd17654", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd17654", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "422744", "url": "https://www.ncbi.nlm.nih.gov/gene/422744", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000873", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000873", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002372", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002372", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009081", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009081", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011047", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011047", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018391", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018391", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020845", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020845", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042099", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042099", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045851", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045851", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048005", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048005", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052091", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052091", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "NGNVICC", "url": "https://omabrowser.org/oma/group/NGNVICC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YIR5", "url": "https://www.orthodb.org/?gene=A0A8V0YIR5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YWW8", "url": "https://www.orthodb.org/?gene=A0A8V0YWW8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR44394", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR44394", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR44394:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR44394:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00501", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00501", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13570", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13570", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001383172", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001383172", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YIR5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIR5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YIR5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIR5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YWW8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YWW8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YWW8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YWW8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRKSNLQYILVENDKIKQFQTAHIDWLSHSSSTVEHIGLTLFHMSRSSTDVNLQADNVKSKLEAFKVMGNSQLGNTVCPEHLKLKTSEGGYRDVGQRCSLAYVLHTSGTTGTPKVVRVPHTCIVPNIQHLKSIFEITQDDVLFLASPLTFDPSVVELFIALTSGASILIVPNAVKMMPVELSTALFNHHHVTVLQATPTLLRRFGAHIIKSTVLSANTSLRVLALGGEAFPVLNLWKSWKHKENKTSIFNLYGITEVSSWATCYRIPEEVFSADFRSDFPVPLGSPLLGTTVEIRDANGSAVLEGEGQIFIGGEERICFLDDEIIVPQGTMRATGDFVRVQNAEIFFLGRKDNQIKRHGKRFNMECLQQAAEDLCQVEACAVTWYQQEKLILFVVPRGDLEERETLHELQKRLPTHGIPDELVQIKALPLTSHGKVDISELNKIYHYHLNSRRRDSKLSGVEELWKRLQYLWKVVLGLLGDSSGISKDAVFLYSGGDSLKALQFYDEIEMLVGRGVPGLLEVILSRSIEEVYKHILKTLFPDEDQLINDDSVLKRKLSKNSGEEIHRKYAKLKSEGYLKVAPGLISFIALSRGNHFFSMNFTKSFIQPSSTVQVEGESLQQPSFLHAVTPSITKSHVRGYEKENRTLTITNKVNKTDCCSVQQTCAECSHVTTAELALRTRWKSNTRKCVDASPLIVISSKDEESASVFVGSHSHAMQAIDLDTGEVKWEKKLGDRIESSACISKCGNFIVVGCYDGLVYVLQSSDGEAYWTFATEDTVKSSAVVDPSSGLVYIGSHDQHMYALDIYEKMCVWKLHCEGGAVFSSPCISSFPHHVYVATLGGLLLAVNPVTGNKIWKSFLGKPLFSSPHCNEKCVCIGCVDGNLYCYTHSGEKVWQFSTNGPVFSSPCISSLTKQEVFFGSHDHFIYCCNTEGNLLWKFEATSSVYGTPFVFQSDDSKNKVLLAAVSTDGKVWILNARSGTAEGIDTLPGEVFSSPIVWGTKLVVGCRNDYVYCLDLYITGKKEQEGC", "length": 1028, "header": "tr|A0A8V0YIR5-1|A0A8V0YIR5_CHICK Isoform 1 of Aminoadipate-semialdehyde dehydrogenase OS=Gallus gallus OX=9031 GN=AASDH PE=3 SV=1 CANONICAL=A0A8V0YIR5-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YIR5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIR5/entry#A0A8V0YIR5-1", "sequence": { "sequence": "MRKSNLQYILVENDKIKQFQTAHIDWLSHSSSTVEHIGLTLFHMSRSSTDVNLQADNVKSKLEAFKVMGNSQLGNTVCPEHLKLKTSEGGYRDVGQRCSLAYVLHTSGTTGTPKVVRVPHTCIVPNIQHLKSIFEITQDDVLFLASPLTFDPSVVELFIALTSGASILIVPNAVKMMPVELSTALFNHHHVTVLQATPTLLRRFGAHIIKSTVLSANTSLRVLALGGEAFPVLNLWKSWKHKENKTSIFNLYGITEVSSWATCYRIPEEVFSADFRSDFPVPLGSPLLGTTVEIRDANGSAVLEGEGQIFIGGEERICFLDDEIIVPQGTMRATGDFVRVQNAEIFFLGRKDNQIKRHGKRFNMECLQQAAEDLCQVEACAVTWYQQEKLILFVVPRGDLEERETLHELQKRLPTHGIPDELVQIKALPLTSHGKVDISELNKIYHYHLNSRRRDSKLSGVEELWKRLQYLWKVVLGLLGDSSGISKDAVFLYSGGDSLKALQFYDEIEMLVGRGVPGLLEVILSRSIEEVYKHILKTLFPDEDQLINDDSVLKRKLSKNSGEEIHRKYAKLKSEGYLKVAPGLISFIALSRGNHFFSMNFTKSFIQPSSTVQVEGESLQQPSFLHAVTPSITKSHVRGYEKENRTLTITNKVNKTDCCSVQQTCAECSHVTTAELALRTRWKSNTRKCVDASPLIVISSKDEESASVFVGSHSHAMQAIDLDTGEVKWEKKLGDRIESSACISKCGNFIVVGCYDGLVYVLQSSDGEAYWTFATEDTVKSSAVVDPSSGLVYIGSHDQHMYALDIYEKMCVWKLHCEGGAVFSSPCISSFPHHVYVATLGGLLLAVNPVTGNKIWKSFLGKPLFSSPHCNEKCVCIGCVDGNLYCYTHSGEKVWQFSTNGPVFSSPCISSLTKQEVFFGSHDHFIYCCNTEGNLLWKFEATSSVYGTPFVFQSDDSKNKVLLAAVSTDGKVWILNARSGTAEGIDTLPGEVFSSPIVWGTKLVVGCRNDYVYCLDLYITGKKEQEGC", "length": 1028, "header": "tr|A0A8V0YIR5-1|A0A8V0YIR5_CHICK Isoform 1 of Aminoadipate-semialdehyde dehydrogenase OS=Gallus gallus OX=9031 GN=AASDH PE=3 SV=1 CANONICAL=A0A8V0YIR5-1" }, "locus": { "chromosome": "4", "start_pos": 64325782, "end_pos": 64309908, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010035862.1", "url": "https://www.ensembl.org/id/ENSGALT00010035862.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020800.1", "url": "https://www.ensembl.org/id/ENSGALP00010020800.1" } ] } }, { "isoform_ac": "A0A8V0YWW8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIR5/entry#A0A8V0YWW8-1", "sequence": { "sequence": "MTLHDMVAQAASLHSGRKAVWFDECNDGPPTFYTYATVIKHATELTAFLQKYCDPQGRCEIGLYCCPGINLPSWILGILQVPAAYCPIDPDAPPLLSAYFMRKSNLQYILVENDKIKQFQTAHIDWLSHSSSTVEHIGLTLFHMSRSSTDVNLQADNVKSKLEAFKVMGNSQLGNTVCPEHLKLKTSEGGYRDVGQRCSLAYVLHTSGTTGTPKVVRVPHTCIVPNIQHLKSIFEITQDDVLFLASPLTFDPSVVELFIALTSGASILIVPNAVKMMPVELSTALFNHHHVTVLQATPTLLRRFGAHIIKSTVLSANTSLRVLALGGEAFPVLNLWKSWKHKENKTSIFNLYGITEVSSWATCYRIPEEVFSADFRW", "length": 377, "header": "tr|A0A8V0YWW8-1|A0A8V0YWW8_CHICK Computationally mapped isoform of Aminoadipate-semialdehyde dehydrogenase OS=Gallus gallus OX=9031 GN=AASDH PE=4 SV=1 CANONICAL=A0A8V0YIR5-1" }, "locus": { "chromosome": "4", "start_pos": 64316831, "end_pos": 64307538, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010035858.1", "url": "https://www.ensembl.org/id/ENSGALT00010035858.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020796.1", "url": "https://www.ensembl.org/id/ENSGALP00010020796.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 629, "start_aa": "Thr", "end_pos": 629, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr629", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A3Q1NC05-1", "protein_name": "Beta-alanine-activating enzyme", "gene_name": "AASDH", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MRSDCIEFLLQTSPPPPATNSMKLLVPLTFLDIEFSATSDVQISVSEMTLQELVHQAASLYSDKIAVCFDECNNQPPVYYTYKTVIHAASALSNFLLLHCEFQGIREIGLYCHPTINLPSWILGILQVPAAYVPVDPDSPPALSVHFMKKCNLKYILVEKVHISKFKSSYEALLNYDMLKVEHNDLVLFRLHWKNVEVSLVLNDRKEKYEKGKMPKSMHSESSSEEKSEEHMDMRQKHCLAYVLHTSGTTGIPKIVRVPHACIVPNIQHFRVLFEITHEDVLFLASPLTFDPSVVEIFVALSSGASLLIVPTSVKMVPSKLAAVLFSHHRVTILQATPTLLRRFGSQLIKSTVLSASTSLRILALGGEAFPSLTVLKSWRGVGNKTQIFNIYGITEVSSWATFYRIPEKILNSTLKCELPVQLGFPLLGTVVEVRDTNGFTIQEGNGQVFLGGRNRVCFLDGEVTVPLGTMRATGDFVTIKDGEIFFLGRKDSQIKRHGKRLNIELVQQIAEGLQQVESCAVTWYNQEKLILFMVTKNDLVKDHIFEELQKHLPSHAIPDELVLINSLPFTSHGKIDVSELNKIYLNYRDLKSECKLSGKEELWEKLHHLWKSVLSLSEDALKIPDESLFLNSGGDSLKSIRLLNEIENLVGTSVPGLLEIILSSSILRIYNHILQTVFSDKDMTLSKNHAMKRKFNVTQEETSGKSLHQETVMPLNCDKEINAFIALSRGNQILSLNTDKYLTKLGHCPSTYSSDLNSQTDIQNRESLNTPPLIGKSEDPSCVVEVSEEETPVIRAEKMEFRVRWRSDTGKCVDASPLVVIPAIDKSSATVYIGSHSHRMIAVDLYSGKVKWEQILGDRIESSACVSKCGNFIVVGCYNGLVYVLKSNSGEKYWMFSTEDAVKSSATMDPTTGLLYIGSHDQHAYALDIYKKKCVWKLKCGGTVFSSPCLSLIPSHLYFATLGGLLLAINPATGDRLWKHSCGKPLFSSPRCCLQYVFIGCVDGNLLCFTHFGEQVWQFSTNEPIFSSPCTSASEQEIFFGSHDCFIYCCSMKGHLQWKFETTSRVYSTPFVFRNHNHNSEMLLAAASTDGKLWILESKSGQLQSVYELPGEVFSSPVVWESMLIIGCRNNYVYCLDVLGDKGNEVQSLEYT", "length": 1153 }, "evidence": [ { "id": "A0A8V0YIR5", "url": "https://omabrowser.org/oma/group/A0A8V0YIR5/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "D4A5F5-1", "protein_name": "Beta-alanine-activating enzyme", "gene_name": "Aasdh", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTLQELVHQAASIYLDRTAVCFDEGNNQPPVCYTYKALLSEASELSAFLLAHCDLGGIREIGLYCQPGINLPSWILGILQIPAAYAPIDPDSLPSLATHFMKKCGLKYVLVEKRQITKFKSSHETVLNYDTVSVEHKDLVLLRLHWEDGAVNSVLSDRTDKCKVNDREERVNGENGSQEKGHMDMRREGCLAYVLHTSGTTGTPKIVRVPHACILPNIQHFRSLFDITQEDVLFLASPLTFDPSVVEIFVALSSGACLLISPTSVKVLPSKLADVLFSRHRVTVLQATPTLLRRFGSELMKSTVLSAHTSLRVLALGGEAFPSLTVLQSWRGKSNRTQIFNIYGITEVSSWATFYRIPEEILNSSVRLESPVQLGSPLLGTVVEVRDKNGSPVHEGTGQVFLGGKNRICFLDEEMTVPLGTMRATGDFVTVKGGEIFFLGRKDSQIKRHGKRLSIALVQQVAEELRQVESCAVTWYNQEKLILFIVSKVDLVKDYIFKELQKHLPAHALPDDMVLIGSLPVTCHGKVDVSELNKIYLDYISSQPRNKLHGKEELWGKLQCLWKSILCLPEDPELKVPDNSVFLDSGGDSLKSLWLLGEVEKLTGAPVPGLLEVILSSSFLDVYNHIIQAVLTREDLKGDRRYTTKRKFSDPDSEETSGKPARLEAAWPWHRDSETNSVVALSRGSQTLYLGTGRLLTELGLCPNAVHPPDLIPQTNTEILKSLSPPALDETLEKPPLSQERSPGTGAEPMVLRERWRSDTGKCVDASPLLVVAAVGDTSSTTVYIGSHSHTVKAVDLHSGEMRWERRVGDRIESSACVSKCGNFIVVGCYDGLVYVLKSNSGEKHWTFPTEDAVKSSPAVDPTTGLIYVGSHDQHAYALDIYEKKCVWKLKCEGALFSSPCLSLGPHHLYCATLGGLLLAVNPATGSLIWKRPCGKPLFSSPRCYQHYVCIGCVDGSLLCFSHSGEQVWRFSAGGPIFSSPCISASEQDIYFGSHDCFLYCCSTEGGLRWKFETTARVYSTPFAFPNHLCGSGTLLAAASTDGKLWVLESQSGELRSVYELPGEVFSSPVVWESMLVIGCRNNYIYCLDLSCGDKNNQV", "length": 1099 }, "evidence": [ { "id": "A0A8V0YIR5", "url": "https://omabrowser.org/oma/group/A0A8V0YIR5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F4K1G2-1", "protein_name": "Putative acyl-activating enzyme 19", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MPKVVALYMPPSVEYVISVFSVLRCGEAFLPLDPSWPRERVLSLISSSNISLVIACGLSSVESHWLVERNVCPVLLFSMDEKLSVETGCSSFVWPCKKERQRKFCYLMYTSGSTGKPKGVCGTEQGLLNRFLWMQELYPVVGEQRFAFKTSVGFIDHIQEFLGAILSSTALVIPPFTLLKENMISIIDFLEEYSISRLLAVPSMIRAILPTLQHRGHNNKLQSCLKLVVLSGEPFPVSLWDSLHSLLPETCFLNLYGSTEVSGDCTYFDCSELPRLLKTEEIGSVPIGKSISNCKVVLLGDEDKPYEGEICVSGLCLSQGYMHSSIESEGYVKLHNNSLCNHLTNDCGSQLYYRTGDYGRQLSSGDLIFIGRRDRTVKLNGKRMALEEIETTLELNPDIAEAVVLLSRDETELASLKAFVVLNKESNSSDGIIFSIRNWMGGKLPPVMIPNHFVLVEKLPLTSSGKVDYEALARLKCPTTGAQDMMQSNGTNSLLQNIKKAVCDALLVKEVSDDDDFFAIGGDSLAAAHLSHSLGIDMRLIYQFRSPSRLLIYLSEKEGKLREDMQHNTTQKLDHKIESQNGNGLVSRTVPLHSGVTSGPTPSKLQCEKNNSPKRLKIDYEKFSPKRMKENKLWDSGFSQIQCAFSRCNKVHSPESCSNEEANREYWSLEIPRNQMVSMQEIWKVHMESCVDASPLVVLKDSKTYLFIGSHSRKFSCIDAKSGSMYWETILEGRIEGSAMVVGDFSQVVIGCYKGKLYFLDFSTGSLCWKFQACGEIKCQPVVDTSSQLIWCGSHDHTLYALDYRSQCCVYKLQCGGSIFASPAIDEGHSSLYVASTSGRVIAVSIKDSPFHTLWLFELEAPIFGSLCITPSTQNVICCLVDGQVIAMSPSGTIIWRYRTGGPIFAGPCMSHVLPSQVLVCCRNGCVYSLEPESGCLVWEDNIGDPITASAYIDENLHFESHELLASDRLVTVCSSSGRVHVLRVRPSILSRDSHDSKVGEITRMELQADIFSSPVMIGGRIFVGCRDDYVHCLSLESCR", "length": 1040 }, "evidence": [ { "id": "A0A8V0YIR5", "url": "https://omabrowser.org/oma/group/A0A8V0YIR5/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q4L235-1", "protein_name": "Beta-alanine-activating enzyme", "gene_name": "AASDH", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTLQELVHKAASCYMDRVAVCFDECNNQLPVYYTYKTVVNAASELSNFLLLHCDFQGIREIGLYCQPGIDLPSWILGILQVPAAYVPIEPDSPPSLSTHFMKKCNLKYILVEKKQINKFKSFHETLLNYDTFTVEHNDLVLFRLHWKNTEVNLMLNDGKEKYEKEKIKSISSEHVNEEKAEEHMDLRLKHCLAYVLHTSGTTGIPKIVRVPHKCIVPNIQHFRVLFDITQEDVLFLASPLTFDPSVVEIFLALSSGASLLIVPTSVKLLPSKLASVLFSHHRVTVLQATPTLLRRFGSQLIKSTVLSATTSLRVLALGGEAFPSLTVLRSWRGEGNKTQIFNVYGITEVSSWATIYRIPEKTLNSTLKCELPVQLGFPLLGTVVEVRDTNGFTIQEGSGQVFLGGRNRVCFLDDEVTVPLGTMRATGDFVTVKDGEIFFLGRKDSQIKRHGKRLNIELVQQVAEELQQVESCAVTWYNQEKLILFMVSKDASVKEYIFKELQKYLPSHAVPDELVLIDSLPFTSHGKIDVSELNKIYLNYINLKSENKLSGKEDLWEKLQYLWKSTLNLPEDLLRVPDESLFLNSGGDSLKSIRLLSEIEKLVGTSVPGLLEIILSSSILEIYNHILQTVVPDEDVTFRKSCATKRKLSDINQEEASGTSLHQKAIMTFTCHNEINAFVVLSRGSQILSLNSTRFLTKLGHCSSACPSDSVSQTNIQNLKGLNSPVLIGKSKDPSCVAKVSEEGKPAIGTQKMELHVRWRSDTGKCVDASPLVVIPTFDKSSTTVYIGSHSHRMKAVDFYSGKVKWEQILGDRIESSACVSKCGNFIVVGCYNGLVYVLKSNSGEKYWMFTTEDAVKSSATMDPTTGLIYIGSHDQHAYALDIYRKKCVWKSKCGGTVFSSPCLNLIPHHLYFATLGGLLLAVNPATGNVIWKHSCGKPLFSSPQCCSQYICIGCVDGNLLCFTHFGEQVWQFSTSGPIFSSPCTSPSEQKIFFGSHDCFIYCCNMKGHLQWKFETTSRVYATPFAFHNYNGSNEMLLAAASTDGKVWILESQSGQLQSVYELPGEVFSSPVVLESMLIIGCRDNYVYCLDLLGGNQK", "length": 1098 }, "evidence": [ { "id": "A0A8V0YIR5", "url": "https://omabrowser.org/oma/group/A0A8V0YIR5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q5RG49-1", "protein_name": "Beta-alanine-activating enzyme", "gene_name": "aasdh", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTAKLLYELVHEAARAHGDKRAVAFDSSIAARVSLTYDELIFMSDELTAQLRVSVQNHEGAIGLFCHPDVLLPVWIIGILQFPAAYLPLDPASPPQCSLRMINNCRLSFCLIQNELLHSAFSILISVEVCATFCSHRLTLIKIKSEQKENSQANDAPFSSAVTKNIQQGEPLAYILHTSGTTGLPKIVKVPHRCIVPNIIHLRSVFKMTPEDVVFLSSPLTFDPSVVEVFLALSSGACLLIVPSAVKKMPRRLAHVLFKRNTTTVLQATPTLVRRFGKVVLQEEVLSADSSLRILAFGGEPCPSLNLVKSWRQEGNRTHIYNLYGTTEVSCWASWYKVPDEHLCLEDITDAPVPLGEPMLDTVMEVRDETGHLVTEGEGQLFIGGQNRVCLLDDEETVVKGTMRATGDWVQVQNSNLYFLGRKDRLVKRFGQRVHLDALQQMIESFSGVEACAVNLSKDDRLLAFIVLTSGHAGAPLSSEIHHDKHLTQPSEISVSVSPKASPPSLRVTEGEIRHQLSKRLSSHSIPDMMVFIPALPLTSHGKIAIDELMKTCETQRQDKNKQAPQKDTASVRLKLQNLWKECLGLQDDVVVEENAHFMFSGGDSLQALRLFDDITVAMGTTSVGLLEVILDGSFSDLLSHIMTETHDDAVLPSKKRTADYSDSEASGKRQHKEMTTSSDTESPFVVPSLRRTMGFVVVRRAAEVFKWGFQKIPQGIFSDAPDKNYVTNNSVGNDTGLISNPSLELSKSSAVTNMADHLQAQEETLLASESPSSHGGVREDSTGVLPLALRVLWRSDTGRCVDASPMLLVAPDRTTVFIGSHSHRLQALDLSRGEVIWERILGDRLESSAAISSCGGLVAIGCYDRQMYFLDVSCGDTVWTFETGDVVKSSPTVDPKTGLVFAGSHDGHVYALNPLTKTCTWQHYCGGGAVFSSPCVHLSPRQLYCSSLGGHLHCLNPDSGKVLWKYSSSAPFFSSPHCSDSSVFIGSVNGHIIGISHSGNTLWDFSTDGPVFSSPCISSLTLLTNQPPSTTPSSSVTTSPNHIVTCGSHDGHVYCLNAQNGSLLWQFQTTGKVFSTPFVFSGALWGLRTLAAVCSTDGKVWVLDGETGIQKATLSLPGELFSSPVIWGSKLVVGCRNDYVYCLELTTQ", "length": 1149 }, "evidence": [ { "id": "A0A8V0YIR5", "url": "https://omabrowser.org/oma/group/A0A8V0YIR5/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q80WC9-1", "protein_name": "Beta-alanine-activating enzyme", "gene_name": "Aasdh", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTLQELVLRTASVYMDRTAVCFDEGNNQPPVCYSYKALLSAASELSHFLIAHCDFGGIREIGLYCQPGINLPSWILGILQVPAAYAPIDPDSPPSLSTYFMKKCDLKYVLVEKQQLSKFKSSHETVLNYDTVSVEHKDLALFRLHWEDGRVSTVLGDRADQHKVTDREDRVSAESRTPEKEHMDMRHDGCLAYVLHTSGTTGTPKIVRVPHACILPNIQHFRSLFDITQEDILFLASPLTFDPSVVEIFVSLSSGACLLIVPTSVKVLPSKLADILFSRHRVTVLQATPTLLRRFGSELIKSTVLSAHTSLRVLALGGEAFPSLTILKSWRGKGNRTQIFNIYGITEVSSWATFYRIPEEILNSAVKHESPVQLGSPLLGTVIEVRDQNGSPVLEGTGQVFLGGKNRVCFLDDEMTVPLGTMRATGDFVTVKDGEIFFLGRKDSQIKRHGKRLNIALVQQVAEELRQVESCAVTWYNQERLILFIVSKVDLVKDCIFKELQKHLPAHALPDDMVLIDTLPFTCHGKVDVSELNKIYLDYISSQPRNELHGKEELWGKLQYLWKSILCLPEDPEDTLKVPANSVFLDSGGDSLKSMRLLSEIERLTGTAIPGLLEVILSSSLLDVYNHIVQAVFTPEDRKANRSYTTKRKFSDADPEEASGKPARLESAWPSNHAGETNSVIALSRGSQVLSLGAGRLLTQLGLCLPVCSLDLIPQTNTQILKSLSPPAPDENLEKPPLFQQGSPVVGAMAMALRERWRSDTGKCVDASPLLVRAAVQDKPSTTVYIGSHSHTVKAVDLSSGETRWEQLLGDRIESSACVSKCGNFIVVGCYNGLVYVLKSNSGEKYWTFTTEDAVKSSPAVDPTTGLIYVGSHDQHAYALDIYEKKCVWKLNCEGALFSSPCVSLSPHHLYCATLGGLLLALNPASGSTVWKRSCGKPLFSSPRCYQQYICIGCVDGSLLCFTHSGEQVWRFAAGGPIFSSPCVSAAEQEIFFGSHDCFIYCCSKEGHLRWKFETTARVYATPFAFSNHPRSDDALLAAASTDGKLWVLESRSGELRSVYELPGEVFSSPVVWESMLVIGCRNNYIYCLDLLCGDKNNQV", "length": 1100 }, "evidence": [ { "id": "A0A8V0YIR5", "url": "https://omabrowser.org/oma/group/A0A8V0YIR5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VLL0-1", "protein_name": "Beta-alanine-activating enzyme", "gene_name": "Aasdh", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MIPSDMDLIESTAEQPDKLYNINRIRAFKDVPFLIRRTESKDTIVSYADAADEIQVLMNFLRKNGVPDEAGIALRVTEHTPASSLMILAILNNKCHFFPTDKMMLSQDLYSQMSTAGVDYLVANKHLTVAPLYFTFLGSILVFKEDCRLYRVKLKSADETVQSKKPLPANMCYTISTTGTTGKPKLIHVPYECIAPNIVGLSQKLNVSMADIIYLGTPITFDPFVVEFFLALQNGATLLTSRHSMRDSPSKVLSALFPDNLATPGITVLQMTPSLFRQFGASSIKDRVLSGSSSLRVLLLGGEPFPSNVELVTWMHPSVLMQKHICNIYGITEISCWSLLHIVQSLQSPVPLGTPIEEDTVLRIESEDNETSQQGELFLGSVKRRCYIPEVDDQANASQDDSGICFRATGDLVTRQQDGTLFYSERSNDVVKRAGNRISLGLITRKIQKCLPSSELTTCLWLEDLQKLICCIRTLESKTRVQQRVQTFDILSKVSIAEQPDRFVYLQHFPCNVHGKLDKQQLLKMCIPLAQPAQQILKSYLHDRLECVEEPDDSASKKQRLDDAAPCGYDLSFRQAGGTSFHAITICREIGLQMCIDDEQRHLFEMLLDENIPLRTVLRFLDTAKLVANNIKRKNVETAVVVSACQSGLIIKRIEQPVLKLQIYWKVNFEKCIDSPVTEYEGRFICVGAHSKILRTLNPQTGSEYSVVKLPERIECKVTFLTEQLAMVGCYDGCLYGFNPQTGNIVFRVGIGGLIKSQPMLTADGRRIIVCSYADDYNVYCLSAERQEVLWCLRIGEKPIFASPLELPREQSLIVCTLDGSYSRVAITDGSVEWTQKFREPVFSTPVLLESVSNIFLSAEVAGRVHACHVGNGKILATFSTEGNIFSSLVVKTPPTFMGHSFAIFGCIDQHLYCLRCKTGPGGKSVELELHWKVDVGAPIYATPTLLTVQPNGLLVWCAATDGRVMLINFRNGEIQWSDKLPGQVFSSACFIEDLRRVFVGCRDNFLYCLGI", "length": 1012 }, "evidence": [ { "id": "A0A8V0YIR5", "url": "https://omabrowser.org/oma/group/A0A8V0YIR5/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "lipid metabolic process", "id": "GO:0006629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006629", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIR5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIR5" } ], "pmid": "" }, { "name": "amino acid activation for nonribosomal peptide biosynthetic process", "id": "GO:0043041", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043041", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIR5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIR5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 217, "end_pos": 219, "annotation": "n_glycosylation_sequon" }, { "start_pos": 244, "end_pos": 246, "annotation": "n_glycosylation_sequon" }, { "start_pos": 298, "end_pos": 300, "annotation": "n_glycosylation_sequon" }, { "start_pos": 600, "end_pos": 602, "annotation": "n_glycosylation_sequon" }, { "start_pos": 644, "end_pos": 646, "annotation": "n_glycosylation_sequon" }, { "start_pos": 654, "end_pos": 656, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YIR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIR5" }, { "id": "PS50075", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50075" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Carrier", "eco_id": "ECO_0000259", "start_pos": 462, "end_pos": 539, "start_aa": "Glu", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 629 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 217, "end_pos": 219 }, { "start_pos": 244, "end_pos": 246 }, { "start_pos": 298, "end_pos": 300 }, { "start_pos": 600, "end_pos": 602 }, { "start_pos": 644, "end_pos": 646 }, { "start_pos": 654, "end_pos": 656 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YIS7-1", "uniprot_ac": "A0A8V0YIS7", "uniprot_id": "A0A8V0YIS7_CHICK", "mass": { "chemical_mass": 22799.0, "monoisotopic_mass": 22799.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "RNase H type-1 domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A8V0YIS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIS7/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIS7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIS7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIS7", "locus": {} } ], "crossref": [ { "id": "A0A8V0YIS7", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YIS7", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR002156", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002156", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012337", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012337", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036397", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036397", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR41694", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR41694", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR41694:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR41694:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00075", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00075", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YIS7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIS7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YIS7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIS7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVEKQLLATYSALQAVEPITQTAEVIVKTTLPIQGWVKDLTHIPKTRVAQSQTVARWVAYLSRRSRLSSSPLKEELQKILGPVTYRSETPEEIVVTCPEKSPVLEGKYPIPEDAWYTDGSSRGNPSRWRAVAYHPSTETIWFEEGDGQSSQWAELRAVWMVITQEPGNSALNICTDSWAVYRGLTLWIAQWATQDWTIHAR", "length": 201, "header": "tr|A0A8V0YIS7-1|A0A8V0YIS7_CHICK Isoform 1 of RNase H type-1 domain-containing protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0YIS7-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YIS7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIS7/entry#A0A8V0YIS7-1", "sequence": { "sequence": "MVEKQLLATYSALQAVEPITQTAEVIVKTTLPIQGWVKDLTHIPKTRVAQSQTVARWVAYLSRRSRLSSSPLKEELQKILGPVTYRSETPEEIVVTCPEKSPVLEGKYPIPEDAWYTDGSSRGNPSRWRAVAYHPSTETIWFEEGDGQSSQWAELRAVWMVITQEPGNSALNICTDSWAVYRGLTLWIAQWATQDWTIHAR", "length": 201, "header": "tr|A0A8V0YIS7-1|A0A8V0YIS7_CHICK Isoform 1 of RNase H type-1 domain-containing protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0YIS7-1" }, "locus": { "chromosome": "W", "start_pos": 2031878, "end_pos": 2031276, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027818.1", "url": "https://www.ensembl.org/id/ENSGALT00010027818.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015952.1", "url": "https://www.ensembl.org/id/ENSGALP00010015952.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "RNA-directed DNA polymerase activity", "id": "GO:0003964", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003964", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIS7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIS7" } ], "pmid": "" }, { "name": "nucleic acid binding", "id": "GO:0003676", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003676", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIS7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIS7" } ], "pmid": "" }, { "name": "RNA-DNA hybrid ribonuclease activity", "id": "GO:0004523", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004523", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIS7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIS7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YIS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIS7" }, { "id": "PS50879", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50879" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RNase H type-1", "eco_id": "ECO_0000259", "start_pos": 109, "end_pos": 201, "start_aa": "Pro", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YIW3-1", "uniprot_ac": "A0A8V0YIW3", "uniprot_id": "A0A8V0YIW3_CHICK", "mass": { "chemical_mass": 50992.0, "monoisotopic_mass": 50992.0 }, "refseq": {}, "gene_names": [ { "name": "NEMP2", "type": "recommended", "evidence": [ { "id": "A0A8V0YIW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIW3" } ] } ], "protein_names": [ { "name": "Nuclear envelope integral membrane protein 2", "type": "synonym", "evidence": [ { "id": "A0A8V0YIW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIW3/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIW3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIW3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "NEMP2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIW3", "locus": { "chromosome": "7", "start_pos": 201766, "end_pos": 188068, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012769", "url": "https://www.ensembl.org/id/ENSGALG00010012769" } ] } } ], "crossref": [ { "id": "A0A8V0YIW3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YIW3", "database": "AlphaFoldDB", "categories": [] }, { "id": "423977", "url": "https://www.ncbi.nlm.nih.gov/gene/423977", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR019358", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019358", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:423977", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423977", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "IWSTLQV", "url": "https://omabrowser.org/oma/group/IWSTLQV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YIW3", "url": "https://www.orthodb.org/?gene=A0A8V0YIW3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13598", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13598", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13598:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13598:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10225", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10225", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001026413", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026413", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YIW3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIW3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YIW3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIW3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGPRRLPWARPGPALGLLLLALAGAVPAAGGSCSLLEEGNAIQKLHEDCFCYVQNRTMHLQYIWSTVQVKINSTRTFRFVPTPEKSNCRNSETVFEFAACAVQILWRPETSTETFLKIKQYGEDFCFRIQPFKEELYTVSMTREMLDGKLLFLFAAGIFLFHFANSLSRSTNFFYLSGIILGVLALLVFVLLALKRFIPRRSTFWILLSGCWMSSLYLIYCFKENMQWLWSEHRIYVLGYFVAVGTLSFATCYQHGPLTSELSITLFTWTLQLTAFVFIYCGVTIPQVAYAIIAVMLCSKGLGYPLAAAWHIGRKMKNDFQSKKVVVRCLTEEEYREQGETETVRALEELRSFCKNPDFSSWLAVSKLQSPHRFAGFVLGSPHVSPAETKAHDEEYGIGSSFLEEQLFETRTESEQDETTSYIHEGDDENEDEIHEPISFPYATELL", "length": 447, "header": "tr|A0A8V0YIW3-1|A0A8V0YIW3_CHICK Isoform 1 of Nuclear envelope integral membrane protein 2 OS=Gallus gallus OX=9031 GN=NEMP2 PE=3 SV=1 CANONICAL=A0A8V0YIW3-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YIW3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIW3/entry#A0A8V0YIW3-1", "sequence": { "sequence": "MGPRRLPWARPGPALGLLLLALAGAVPAAGGSCSLLEEGNAIQKLHEDCFCYVQNRTMHLQYIWSTVQVKINSTRTFRFVPTPEKSNCRNSETVFEFAACAVQILWRPETSTETFLKIKQYGEDFCFRIQPFKEELYTVSMTREMLDGKLLFLFAAGIFLFHFANSLSRSTNFFYLSGIILGVLALLVFVLLALKRFIPRRSTFWILLSGCWMSSLYLIYCFKENMQWLWSEHRIYVLGYFVAVGTLSFATCYQHGPLTSELSITLFTWTLQLTAFVFIYCGVTIPQVAYAIIAVMLCSKGLGYPLAAAWHIGRKMKNDFQSKKVVVRCLTEEEYREQGETETVRALEELRSFCKNPDFSSWLAVSKLQSPHRFAGFVLGSPHVSPAETKAHDEEYGIGSSFLEEQLFETRTESEQDETTSYIHEGDDENEDEIHEPISFPYATELL", "length": 447, "header": "tr|A0A8V0YIW3-1|A0A8V0YIW3_CHICK Isoform 1 of Nuclear envelope integral membrane protein 2 OS=Gallus gallus OX=9031 GN=NEMP2 PE=3 SV=1 CANONICAL=A0A8V0YIW3-1" }, "locus": { "chromosome": "7", "start_pos": 199549, "end_pos": 188105, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030592.1", "url": "https://www.ensembl.org/id/ENSGALT00010030592.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017748.1", "url": "https://www.ensembl.org/id/ENSGALP00010017748.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:423977", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423977", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A6NFY4-1", "protein_name": "Nuclear envelope integral membrane protein 2", "gene_name": "NEMP2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGPRQGRWWLLLWLPPLATLPVRGEAAAAALSVRRCKALKEKDLIRTSESDCYCYNQNSQVEWKYIWSTMQVKITSPGLFRIVYIAERHNCQYPENILSFIKCVIHNFWIPKESNEITIIINPYRETVCFSVEPVKKIFNYMIHVNRNIMDFKLFLVFVAGVFLFFYARTLSQSPTFYYSSGTVLGVLMTLVFVLLLVKRFIPKYSTFWALMVGCWFASVYIVCQLMEDLKWLWYENRIYVLGYVLIVGFFSFVVCYKHGPLADDRSRSLLMWMLRLLSLVLVYAGVAVPQFAYAAIILLMSSWSLHYPLRACSYMRWKMEQWFTSKELVVKYLTEDEYREQADAETNSALEELRRACRKPDFPSWLVVSRLHTPSKFADFVLGGSHLSPEEISLHEEQYGLGGAFLEEQLFNPSTA", "length": 417 }, "evidence": [ { "id": "A0A8V0YIW3", "url": "https://omabrowser.org/oma/group/A0A8V0YIW3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "F1MML1-1", "protein_name": "Nuclear envelope integral membrane protein 2", "gene_name": "NEMP2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MRLTPETCWLLLWLPPLAAQPAGGERGEEEAAAVSVSTCQVLKEMKIIKASLSGCYCYNQNSQVQWKYIWSTVQVKINSSDLFNVVYITERYNCQYPETILSIIRCMIHNFWTPEESNDITITIHPYGQTVCFSVKPARKIFIYTISVKQNIVDFKLVFVFVVGIFLFFYAKTLSRSPVFFYSSGTVLGVLMTLVFVLLLVKKFIPKYSTFWALMLGCWFASVYILGQLMEELKRLWYEGRICVLGYILTVGCVSFAVCYKHGPLVEERSVVLLAWLLRLLSLLLVYMGVSAPQFACTAALLLFLSSGSRCYPRSVLACVGRKMKKWFTSEKPAVKFLTEDEYREQADAATTCALEELRQACRSPGFPSWLAVSRLQEPKKFADFVLGGSHLSPEEVRLHEEQYGLGGAFLEEQLFHLRTPDSLPAQ", "length": 427 }, "evidence": [ { "id": "A0A8V0YIW3", "url": "https://omabrowser.org/oma/group/A0A8V0YIW3/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1QYC4-1", "protein_name": "Nuclear envelope integral membrane protein 2", "gene_name": "nemp2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEKLAAFILVLTLLCAYWQSAEGIREYSYADCTDVKGDSAHRYSGSRCFCYSPGTVIKWKDIWSTFKVNVSSNVDVVVVFPMETINCHHPDDLLTVMNCFVEHYWPSTVQRETSLEIPLVDVDICFMIKSPRSNTEYTLHVSNKRLNRMCFLLFVCGLILFFGARNICRSSLFFYTTGVSLGIIATFVFLTLLLRNFVPKRGLFLVLLGAGSGLSYMGIQRVLNEWDDIVTEHWMELLAYVLISGLFSFAVCYKHGPITNKHTLNFMTCSMQAVGIVLLYYGITFPPAYFVLVAVLLCWKILPLAWSLLMGICSLFYSFLALFRRRRRPTVRLLTEEEYREQGEIHTRASLDELREYCNRPGFPAWETVLRLRSPQRFAEFLRQGSHITQEEHQNHENHYGLGGAYYENVIFNNSSSSDTQSHREEAEDNSEDEIVGNSPPVLNNLPSPTIYPPTICPYPPVTYTPQPEPLDPEDQDFF", "length": 479 }, "evidence": [ { "id": "A0A8V0YIW3", "url": "https://omabrowser.org/oma/group/A0A8V0YIW3/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "P0C8N6-1", "protein_name": "Nuclear envelope integral membrane protein 2", "gene_name": "Nemp2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPPGSWWLVLWLPPLATLPAGAVPQEEAAMSVPRCKSLKETDLIKTSVSDCYCYNQHSQIEWTYMWSTVQVTVTSPGLLSIVYITGRHTCQHTETILSFLKCVTHNFWTAEEAKEVTIVFSPYGETVCFSVKPVGSLLTYAVSVNRNVVDFRLFLVFATGIFLFFYAKTLSQSPVFYYSSGTVLGILMTLVFVLLMTKKHIPKYSTFGALMIGCWFASVYVLCQLMENLKWLWCGNRIYVLGYVLVVGLCSFSACYSRGPPADEGSRDLLMWALRFLSLVLVYTGMAISQFAYAVMILLLLSWTRHYLLRAFSCLRWKVRQWFATRALVVRYLTDDEYREQAEAETASALEELRQACCRPDFPSWLAVSRLQAPKKFAEFVLGASHLSPEEVSTHEKQYGLGGAFLEEQLFSLQTESLPAS", "length": 421 }, "evidence": [ { "id": "A0A8V0YIW3", "url": "https://omabrowser.org/oma/group/A0A8V0YIW3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8CB65-1", "protein_name": "Nuclear envelope integral membrane protein 2", "gene_name": "Nemp2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLPRLWWLVLWLQPLATLPASAVHDEEAAMSVPRCKSLKETDLIKTSVSDCYCYNQHSQIQWTYMWSTVQVTVTSPGLLNIVYITGSHNCQHTESILSFIKCVTHNFWAPEEAEEITIVFSPYGETVCFSVKPVGRLLPYIVSVSRNIVDFKLFLVFVTGIFLFLYAKTLSQSPVFYYSSGTVLGILMTLVFVLLMAKKHIPKYSTFGALMIGCWFASVYVLCQLMEDLKWLWYGNRMYILGYVVVVGLCSFAACYSHGPLADEGSRDLLMWTLRLFSLALVYTGVAAPQFAYAVLIVLLFSWSLHYLLRAFSYLRWKMRPWFTAEPQVARYLTDDEYREQAEAATARALEELRQACCRPDFPSWLAVSRLQAPKKFAEFVLGASHLSPEEVSTHEKQYGLGGAFLEEQLFSLQTDSLPAS", "length": 421 }, "evidence": [ { "id": "A0A8V0YIW3", "url": "https://omabrowser.org/oma/group/A0A8V0YIW3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nuclear envelope", "id": "GO:0005635", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005635", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YIW3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIW3" } ], "pmid": "" }, { "name": "nuclear inner membrane", "id": "GO:0005637", 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"sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YJ12-1", "uniprot_ac": "A0A8V0YJ12", "uniprot_id": "A0A8V0YJ12_CHICK", "mass": { "chemical_mass": 57642.0, "monoisotopic_mass": 57642.0 }, "refseq": {}, "gene_names": [ { "name": "HNRNPH1", "type": "recommended", "evidence": [ { "id": "A0A8V0YJ12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ12" } ] } ], "protein_names": [ { "name": "Heteroous nuclear ribonucleoprotein H1", "type": "synonym", "evidence": [ { "id": "A0A8V0YJ12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ12/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJ12", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ12" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "HNRNPH1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ12", "locus": { "chromosome": "13", "start_pos": 13196571, "end_pos": 13179904, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010014967", "url": "https://www.ensembl.org/id/ENSGALG00010014967" } ] } } ], "crossref": [ { "id": "A0A8V0YJ12", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YJ12", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd12729", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12729", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd12731", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12731", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd12734", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12734", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "395157", "url": "https://www.ncbi.nlm.nih.gov/gene/395157", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000504", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000504", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012677", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012677", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012996", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012996", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050666", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050666", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "SKWDWRA", "url": "https://omabrowser.org/oma/group/SKWDWRA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YJ12", "url": "https://www.orthodb.org/?gene=A0A8V0YJ12", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YJ34", "url": "https://www.orthodb.org/?gene=A0A8V0YJ34", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YS69", "url": "https://www.orthodb.org/?gene=A0A8V0YS69", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YX91", "url": "https://www.orthodb.org/?gene=A0A8V0YX91", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13976", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13976", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF08080", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08080", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF28441", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF28441", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-72163", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-72163", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9770562", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9770562", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YJ12", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ12", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJ12-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ12-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJ34", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ34", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJ34-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ34-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YS69", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YS69", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YS69-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YS69-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YX91", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YX91", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YX91-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YX91-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDPCHTEETEGEIPGLGFSDRSEQIVSRGVASAFEAATTETEAEPNLTSNVMLNTESSEGYVVKVRGLPWSCSTEEVQRFFSDCKILNGALGIRFIYTREGRPSGEAFAELESEEDVKLALKKDRETMGHRYVEVFKSNNVEMDWVLKHTGPNSPDTANDGFVRLRGLPFGCSKEEIVQFFSGLEIVPNGITLPVDFQGRSTGEAFVQFASQEIAEKALKKHKERIGHRYIEIFKSSRAEVRTHYDPPRKLMAMQRPGPYDRPGLTRGYNSLGRGSGLERMRRGAYGGGYGGYDDYNGYNDGYGFGSDRFGRDLEWTLFSAGMSDHRYGDGTSTFQSTTGHCVHMRGLPYRATENDIYNFFSPLNPVRVHIEIGPDGRVTGEADVEFATHEDAVAAMSKDKANMQHRYVELFLNSTAGGTGGAYGSQMMGAMAFYLNHTVKESEGVVQDWNTSTLAGSQSSYGGPANQQLSGGYGGGYGGQSSMSGYDPGSQGAMNSSYYSSGNRASMGVNGMGGMSNMSNMSGGWGM", "length": 528, "header": "tr|A0A8V0YJ12-1|A0A8V0YJ12_CHICK Isoform 1 of Heteroous nuclear ribonucleoprotein H1 OS=Gallus gallus OX=9031 GN=HNRNPH1 PE=1 SV=1 CANONICAL=A0A8V0YJ12-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YJ12-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ12/entry#A0A8V0YJ12-1", "sequence": { "sequence": "MDPCHTEETEGEIPGLGFSDRSEQIVSRGVASAFEAATTETEAEPNLTSNVMLNTESSEGYVVKVRGLPWSCSTEEVQRFFSDCKILNGALGIRFIYTREGRPSGEAFAELESEEDVKLALKKDRETMGHRYVEVFKSNNVEMDWVLKHTGPNSPDTANDGFVRLRGLPFGCSKEEIVQFFSGLEIVPNGITLPVDFQGRSTGEAFVQFASQEIAEKALKKHKERIGHRYIEIFKSSRAEVRTHYDPPRKLMAMQRPGPYDRPGLTRGYNSLGRGSGLERMRRGAYGGGYGGYDDYNGYNDGYGFGSDRFGRDLEWTLFSAGMSDHRYGDGTSTFQSTTGHCVHMRGLPYRATENDIYNFFSPLNPVRVHIEIGPDGRVTGEADVEFATHEDAVAAMSKDKANMQHRYVELFLNSTAGGTGGAYGSQMMGAMAFYLNHTVKESEGVVQDWNTSTLAGSQSSYGGPANQQLSGGYGGGYGGQSSMSGYDPGSQGAMNSSYYSSGNRASMGVNGMGGMSNMSNMSGGWGM", "length": 528, "header": "tr|A0A8V0YJ12-1|A0A8V0YJ12_CHICK Isoform 1 of Heteroous nuclear ribonucleoprotein H1 OS=Gallus gallus OX=9031 GN=HNRNPH1 PE=1 SV=1 CANONICAL=A0A8V0YJ12-1" }, "locus": { "chromosome": "13", "start_pos": 13195475, "end_pos": 13180640, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010036011.1", "url": "https://www.ensembl.org/id/ENSGALT00010036011.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020905.1", "url": "https://www.ensembl.org/id/ENSGALP00010020905.1" } ] } }, { "isoform_ac": "A0A8V0YJ34-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ12/entry#A0A8V0YJ34-1", "sequence": { "sequence": "MDPCHTEETEGEIPGLGFSDRSEQIVSRGVASAFEAATTETEAEPNLTSNVMLNTESSEGYVVKVRGLPWSCSTEEVQRFFSDCKILNGALGIRFIYTREGRPSGEAFAELESEEDVKLALKKDRETMGHRYVEVFKSNNVEMDWVLKHTGPNSPDTANDGFVRLRGLPFGCSKEEIVQFFSGLEIVPNGITLPVDFQGRSTGEAFVQFASQEIAEKALKKHKERIGHRYIEIFKSSRAEVRTHYDPPRKLMAMQRPGPYDRPGLTRGYNSLGRGSGLERMRRGAYGGGYGGYDDYNGYNDGYGFGSDRFGRDLEWTLFSAGMSDHRYGDGTSTFQSTTGHCVHMRGLPYRATENDIYNFFSPLNPVRVHIEIGPDGRVTGEADVEFATHEDAVAAMSKDKANMQHRYVELFLNSTAGGTGGAYGSQMMGAMVKESEGVVQDWNTSTLAGSQSSYGGPANQQLSGGYGGGYGGQSSMSGYDPGSQGAMNSSYYSSGNRASMGVNGMGGMSNMSNMSGGWGM", "length": 521, "header": "tr|A0A8V0YJ34-1|A0A8V0YJ34_CHICK Computationally mapped isoform of Heteroous nuclear ribonucleoprotein H1 OS=Gallus gallus OX=9031 GN=HNRNPH1 PE=1 SV=1 CANONICAL=A0A8V0YJ12-1" }, "locus": { "chromosome": "13", "start_pos": 13195475, "end_pos": 13180640, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010036049.1", "url": "https://www.ensembl.org/id/ENSGALT00010036049.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020930.1", "url": "https://www.ensembl.org/id/ENSGALP00010020930.1" } ] } }, { "isoform_ac": "A0A8V0YS69-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ12/entry#A0A8V0YS69-1", "sequence": { "sequence": "MSTTETEAEPNLTSNVMLNTESSEGYVVKVRGLPWSCSTEEVQRFFSDCKILNGALGIRFIYTREGRPSGEAFAELESEEDVKLALKKDRETMGHRYVEVFKSNNVEMDWVLKHTGPNSPDTANDGFVRLRGLPFGCSKEEIVQFFSGLEIVPNGITLPVDFQGRSTGEAFVQFASQEIAEKALKKHKERIGHRYIEIFKSSRAEVRTHYDPPRKLMAMQRPGPYDRPGLTRGYNSLGRGSGLERMRRGAYGGGYGGYDDYNGYNDGYGFGSDRFGREWTLFSAGMSDHRYGDGTSTFQSTTGHCVHMRGLPYRATENDIYNFFSPLNPVRVHIEIGPDGRVTGEADVEFATHEDAVAAMSKDKANMQHRYVELFLNSTAGGTGGAYGSQMMGAMVKESEGVVQDWNTSTLAGSQSSYGGPANQQLSGGYGGGYGGQSSMSGYDPGSQGAMNSSYYSSGNRASMGVNGMGGMSNMSNMSGGWGM", "length": 484, "header": "tr|A0A8V0YS69-1|A0A8V0YS69_CHICK Computationally mapped isoform of Heteroous nuclear ribonucleoprotein H1 OS=Gallus gallus OX=9031 GN=HNRNPH1 PE=1 SV=1 CANONICAL=A0A8V0YJ12-1" }, "locus": { "chromosome": "13", "start_pos": 13195475, "end_pos": 13188146, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010036029.1", "url": "https://www.ensembl.org/id/ENSGALT00010036029.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020918.1", "url": "https://www.ensembl.org/id/ENSGALP00010020918.1" } ] } }, { "isoform_ac": "A0A8V0YX91-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ12/entry#A0A8V0YX91-1", "sequence": { "sequence": "MDPCHTEETEGEIPGLATTETEAEPNLTSNVMLNTESSEGYVVKVRGLPWSCSTEEVQRFFSDCKILNGALGIRFIYTREGRPSGEAFAELESEEDVKLALKKDRETMGHRYVEVFKSNNVEMDWVLKHTGPNSPDTANDGFVRLRGLPFGCSKEEIVQFFSGLEIVPNGITLPVDFQGRSTGEAFVQFASQEIAEKALKKHKERIGHRYIEIFKSSRAEVRTHYDPPRKLMAMQRPGPYDRPGLTRGYNSLGRGSGLERMRRGAYGGGYGGYDDYNGYNDGYGFGSDRFGRGMSDHRYGDGTSTFQSTTGHCVHMRGLPYRATENDIYNFFSPLNPVRVHIEIGPDGRVTGEADVEFATHEDAVAAMSKDKANMQHRYVELFLNSTAGGTGGAYGSQMMGAMVKESEGVVQDWNTSTLAGSQSSYGGPANQQLSGGYGGGYGGQSSMSGYDPGSQGAMNSSYYSSGNRASMGVNGMGGMSNMSNMSGGWGM", "length": 492, "header": "tr|A0A8V0YX91-1|A0A8V0YX91_CHICK Computationally mapped isoform of Heteroous nuclear ribonucleoprotein H1 OS=Gallus gallus OX=9031 GN=HNRNPH1 PE=1 SV=1 CANONICAL=A0A8V0YJ12-1" }, "locus": { "chromosome": "13", "start_pos": 13195475, "end_pos": 13180640, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010036042.1", "url": "https://www.ensembl.org/id/ENSGALT00010036042.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020926.1", "url": "https://www.ensembl.org/id/ENSGALP00010020926.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-72163", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-72163", "resource": "Reactome", "description": "mRNA Splicing - Major Pathway" }, { "id": "R-GGA-9770562", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9770562", "resource": "Reactome", "description": "mRNA Polyadenylation" } ], "orthologs": [ { "uniprot_canonical_ac": "O35737-1", "protein_name": "Heterogeneous nuclear ribonucleoprotein H", "gene_name": "Hnrnph1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MMLGAEGGEGFVVKVRGLPWSCSADEVQRFFSDCKIQNGAQGIRFIYTREGRPSGEAFVELESEDEVKLALKKDRETMGHRYVEVFKSNNVEMDWVLKHTGPNSPDTANDGFVRLRGLPFGCSKEEIVQFFSGLEIVPNGITLPVDFQGRSTGEAFVQFASQEIAEKALKKHKERIGHRYIEIFKSSRAEVRTHYDPPRKLMAMQRPGPYDRPGAGRGYNSIGRGAGFERMRRGAYGGGYGGYDDYNGYNDGYGFGSDRFGRDLNYCFSGMSDHRYGDGGSTFQSTTGHCVHMRGLPYRATENDIYNFFSPLNPVRVHIEIGPDGRVTGEADVEFATHEDAVAAMSKDKANMQHRYVELFLNSTAGASGGAYEHRYVELFLNSTAGASGGAYGSQMMGGMGLSNQSSYGGPASQQLSGGYGGGYGGQSSMSGYDQVLQENSSDFQSNIA", "length": 449 }, "evidence": [ { "id": "A0A8V0YJ12", "url": "https://omabrowser.org/oma/group/A0A8V0YJ12/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P31943-1", "protein_name": "Heterogeneous nuclear ribonucleoprotein H", "gene_name": "HNRNPH1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MMLGTEGGEGFVVKVRGLPWSCSADEVQRFFSDCKIQNGAQGIRFIYTREGRPSGEAFVELESEDEVKLALKKDRETMGHRYVEVFKSNNVEMDWVLKHTGPNSPDTANDGFVRLRGLPFGCSKEEIVQFFSGLEIVPNGITLPVDFQGRSTGEAFVQFASQEIAEKALKKHKERIGHRYIEIFKSSRAEVRTHYDPPRKLMAMQRPGPYDRPGAGRGYNSIGRGAGFERMRRGAYGGGYGGYDDYNGYNDGYGFGSDRFGRDLNYCFSGMSDHRYGDGGSTFQSTTGHCVHMRGLPYRATENDIYNFFSPLNPVRVHIEIGPDGRVTGEADVEFATHEDAVAAMSKDKANMQHRYVELFLNSTAGASGGAYEHRYVELFLNSTAGASGGAYGSQMMGGMGLSNQSSYGGPASQQLSGGYGGGYGGQSSMSGYDQVLQENSSDFQSNIA", "length": 449 }, "evidence": [ { "id": "A0A8V0YJ12", "url": "https://omabrowser.org/oma/group/A0A8V0YJ12/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q6AY09-1", "protein_name": "Heterogeneous nuclear ribonucleoprotein H2", "gene_name": "Hnrnph2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MMLSTEGREGFVVKVRGLPWSCSAEEVMRFFSDCKIQNGTSGVRFIYTREGRPSGEAFVELESEDEVKLALKKDRETMGHRYVEVFKSNSVEMDWVLKHTGPNSPDTANDGFVRLRGLPFGCSKEEIVQFFSGLEIVPNGMTLPVDFQGRSTGEAFVQFASQEIAEKALKKHKERIGHRYIEIFKSSRAEVRTHYDPPRKLMTMQRPGPYDRPGAGRGYNSIGRGAGFERMRRGAYGGGYGGYDDYGGYNDGYGFGSDRFGRDLNYCFSGMSDHRYGDGGSSFQSTTGHCVHMRGLPYRATENDIYNFFSPLNPMRVHIEIGPDGRVTGEADVEFATHEDAVAAMAKDKANMQHRYVELFLNSTAGTSGGAYDHSYVELFLNSTAGASGGAYGSQMMGGMGLSNQSSYGGPASQQLSAGYGGGYGGQSSMSGYDQVLQENSSDYQSNLA", "length": 449 }, "evidence": [ { "id": "A0A8V0YJ12", "url": "https://omabrowser.org/oma/group/A0A8V0YJ12/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJ12", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ12" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJ12", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ12" } ], "pmid": "" }, { "name": "ribonucleoprotein complex", "id": "GO:1990904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990904", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJ12", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ12" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "regulation of RNA splicing", "id": "GO:0043484", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043484", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJ12", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ12" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 414, "end_pos": 416, "annotation": "n_glycosylation_sequon" }, { "start_pos": 437, "end_pos": 439, "annotation": 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"id": "IPR024606", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024606", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:100857885", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100857885", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YTWCASC", "url": "https://omabrowser.org/oma/group/YTWCASC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YCM7", "url": "https://www.orthodb.org/?gene=A0A8V0YCM7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YCN2", "url": "https://www.orthodb.org/?gene=A0A8V0YCN2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YJ32", "url": "https://www.orthodb.org/?gene=A0A8V0YJ32", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YL04", "url": "https://www.orthodb.org/?gene=A0A8V0YL04", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YL08", "url": "https://www.orthodb.org/?gene=A0A8V0YL08", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21590", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21590", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21590:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21590:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF12877", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12877", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015143070", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015143070", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YCM7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCM7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YCM7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCM7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YCN2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCN2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YCN2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCN2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJ32", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ32", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJ32-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ32-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YL04", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL04", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YL04-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL04-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YL08", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL08", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YL08-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL08-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAGMTRFAARWRSALPALLPLLLAVPALRGSPAADEMSSEQRNFSFFSMDSKVHQSISGSRTQMALAESTLESQESHFLQTLLSSVTTPIDATSFNQEETARTSEGKSTPLIDFSVTSNEAFLSDDKFISPFPKVQWTPPLKSFAILTDHHSDNTVEAPRETLETPLLTPSLSIFSSPYDILGTAQQKTPLSAVLDYSTSLTELEPFVPDSGILTASRHLPLYPPDTGIYFTPVPSEEVDAMWENINRSVTSLPSGATSEGSPVHLKLLGENSHAAAGATARSGDIYTRMSSRATEAVGVRTDPAPSVPWAIVAATVSAESALFSISLPFATFPGHSAAMSTYPDTVLNAGLFTQKFSSTAPNLPADSEIPSQSELDTELISPVPFTRSYSSCLYCDSVSLLPEAGFSPEHDVGSGDYVETLSFTASEVQGVTPFTTVITDKYELEEPTPEIFDTSFPSRPVVSFSSRFAEIHDSTLFLLSTVDTALDDRKPESSPSYHELPGETSLDISGFQFSLPVAGTVSLAPNTRVEDPATSTVLLETATIPSHLVASHAVSPTTWLESPELKPSESVFLFDKTSTREELSLNISDFSSNLLSTPFLIEPSYLLVSSAVLTSHSVMQSDFSTLLPQTSLTGTSLLSEDVSSWDLATAVSSATDSEVSLFSVGQISYFYSNASSVPGAPVPEIIPSSGFPSGSSVFLEASSVLPVGSEAMFTSAVSGATSQLEPSPSSLQYVAPTLVLPASDTGPLRSSVLLDETNLISVFTTFPTTPILNASSSLLSTGLASDEDIGATVKASLLLTSLSESSTHTTALLTADPDGPTQHADASSILPSPTESLSATTLFVPTQFPLTSLPPTGYDVPTGAGDADTSVAASTIPTTAATSTTGRSSVSSSPPLVTSTRPGATILPSATSTTRQPYVCDIAVPDVYLVTAVLARRAVLQNVSESIREVLRAQFRRSVELEVYKISPKFAFLVTSGPFVYTAIAVINVLVNSSLLRGSAPPILSLQPSFTVPDSRFQVQTVLQFVPRNMDIGFCNFSQRIEKGLTMAFMEVSKQHQEFYNFTVQILNITLSRPGAAFRQGPVSIIFAIRDRYGFLNGSEVSEQLRNLSVVEFSFYLGFPVQQIAEPFHYPKLNVSQLMKSSWVRTVLLGVVDQRIQEEVFQAEMERKLAHLLNEALARGRIWRRASFAGSNIVQIVNVSRLDGVDNPVELIYFVEDQDGERFSALKCSDLMNRVDIQRAAIILGYRIDGTVAQPVEKLKESSSEAQNSNLWIIVGVAVPVAVVLLIVIILYWKLCRTDKLEFQPDTISNIQQRQKLQAPSVKGFDFAKQHLGQHNKDDVLIIHEPAPLPGPIKDTTPSENGDVPSPKSKTSSKPSKTVRHRGRVSPSDADSTASEQSSGRETGEETARPSAVANEGKPRRATKKGPPQSSSGNEQHSSASIFEHVDRMSRSSDASRRVPSKIQLIAMQPMAAPPVQNSVLSDRVAETNKINKEIQTALRHKSEIEHHRNKIRLRAKRKGHYEFPVVDDVVVVDSKEQHRIYRKAQMQIDKILDPGGSVPTVFIEPRKSSRAKRSPKQRRRHQINGSPIDAEKDRLITTDSDGTYKRPPGVNNSAYISDPDLPPEPQTSSSADLGKFPGLPSHPVSQYVPPQPSIEEARQTMHSLLDDAFALVAPSSQAASSTAVTPPGVSAGQPRYVEFGMTPPAAPGLLPRQNFGPGFLQPAELMHPDQQPPEVQYSSRGIYSEEMPSMARPRPVGSTAGSQIQHLTQVGIASRIGGQQVEIPSGRAGHGQPGGPGWPQYRGEDEYARRDAMHMHGHQEYSSSPVFQMPRTSARQPSVPPAQLPHNNLQGQGLCYTTSSTEDLQPGHSSASLIKAIREELLRLSQKQTTVQNFHS", "length": 1898, "header": "tr|A0A8V0YJ32-1|A0A8V0YJ32_CHICK Isoform 1 of KIAA1549 OS=Gallus gallus OX=9031 GN=KIAA1549 PE=4 SV=1 CANONICAL=A0A8V0YJ32-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YCM7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ32/entry#A0A8V0YCM7-1", "sequence": { "sequence": "MFSDEMSSEQRNFSFFSMDSKVHQSISGSRTQMALAESTLESQESHFLQTLLSSVTTPIDATSFNQEETARTSEGKSTPLIDFSVTSNEAFLSDDKFISPFPKVQWTPPLKSFAILTDHHSDNTVEAPRETLETPLLTPSLSIFSSPYDILGTAQQKTPLSAVLDYSTSLTELEPFVPDSGILTASRHLPLYPPDTGIYFTPVPSEEVDAMWENINRSVTSLPSGATSEGSPVHLKLLGENSHAAAGATARSGDIYTRMSSRATEAVGVRTDPAPSVPWAIVAATVSAESALFSISLPFATFPGHSAAMSTYPDTVLNAGLFTQKFSSTAPNLPADSEIPSQSELDTELISPVPFTRSYSSCLYCDSVSLLPEAGFSPEHDVGSGDYVETLSFTASEVQGVTPFTTVITDKYELEEPTPEIFDTSFPSRPVVSFSSRFAEIHDSTLFLLSTVDTALDDRKPESSPSYHELPGETSLDISGFQFSLPVAGTVSLAPNTRVEDPATSTVLLETATIPSHLVASHAVSPTTWLESPELKPSESVFLFDKTSTREELSLNISDFSSNLLSTPFLIEPSYLLVSSAVLTSHSVMQSDFSTLLPQTSLTGTSLLSEDVSSWDLATAVSSATDSEVSLFSVGQISYFYSNASSVPGAPVPEIIPSSGFPSGSSVFLEASSVLPVGSEAMFTSAVSGATSQLEPSPSSLQYVAPTLVLPASDTGPLRSSVLLDETNLISVFTTFPTTPILNASSSLLSTGLASDEDIGATVKASLLLTSLSESSTHTTALLTADPDGPTQHADASSILPSPTESLSATTLFVPTQFPLTSLPPTGYDVPTGAGDADTSVAASTIPTTAATSTTGRSSVSSSPPLVTSTRPGATILPSATSTTRQPYVCDIAVPDVYLVTAVLARRAVLQNVSESIREVLRAQFRRSVELEVYKISPKFAFLVTSGPFVYTAIAVINVLVNSSLLRGSAPPILSLQPSFTVPDSRFQVQTVLQFVPRNMDIGFCNFSQRIEKGLTMAFMEVSKQHQEFYNFTVQILNITLSRPGAAFRQGPVSIIFAIRDRYGFLNGSEVSEQLRNLSVVEFSFYLGFPVQQIAEPFHYPKLNVSQLMKSSWVRTVLLGVVDQRIQEEVFQAEMERKLAHLLNEALARGRIWRRASFAGSNIVQIVNVSRLDGVDNPVELIYFVEDQDGERFSALKCSDLMNRVDIQRAAIILGYRIDGTVAQPVEKLKESSSEAQNSNLWIIVGVAVPVAVVLLIVIILYWKLCRTDKLEFQPDTISNIQQRQKLQAPSVKGFDFAKQHLGQHNKDDVLIIHEPAPLPGPIKDTTPSENGDVPSPKSKTSSKPSKTVRHRGRVSPSDADSTASEQSSGRETGEETARPSAVANEGKPRRATKKGPPQSSSGNEQHSSASIFEHVDRMSRSSDASRRVPSKIQLIAMQPMAAPPVQNSVLSDRVAETNKINKEIQTALRHKSEIEHHRNKIRLRAKRKGHYEFPVVDDVVVVDSKEQHRIYRKAQMQIDKILDPGGSVPTVFIEPRKSSRAKRSPKQRRRHQINGSPIDAEKDRLITTDSDGTYKRPPGVNNSAYISDPDLPPEPQTSSSADLGKFPGLPSHPVSQYVPPQPSIEEARQTMHSLLDDAFALVAPSSQAASSTAVTPPGVSAGQPRYVEFGMTPPAAPGLLPRQNFGPGFLQPAELMHPDQQPPEVQYSSRGIYSEEMPSMARPRPVGSTAGSQIQHLTQVGIASRIGGQQVEIPSGRAGHGQPGGPGWPQYRGEDEYARRDAMHMHGHQEYSSSPVFQMPRTSARQPSVPPAQLPHNNLQGQGLCYTTSSTEDLQPGHSSASLIKAIREELLRLSQKQTTVQNFHS", "length": 1867, "header": "tr|A0A8V0YCM7-1|A0A8V0YCM7_CHICK Computationally mapped isoform of KIAA1549 OS=Gallus gallus OX=9031 GN=KIAA1549 PE=4 SV=1 CANONICAL=A0A8V0YJ32-1" }, "locus": { "chromosome": "1", "start_pos": 56354133, "end_pos": 56249292, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031708.1", "url": "https://www.ensembl.org/id/ENSGALT00010031708.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018556.1", "url": "https://www.ensembl.org/id/ENSGALP00010018556.1" } ] } }, { "isoform_ac": "A0A8V0YCN2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ32/entry#A0A8V0YCN2-1", "sequence": { "sequence": "MKPSSFEYEMSSEQRNFSFFSMDSKVHQSISGSRTQMALAESTLESQESHFLQTLLSSVTTPIDATSFNQEETARTSEGKSTPLIDFSVTSNEAFLSDDKFISPFPKVQWTPPLKSFAILTDHHSDNTVEAPRETLETPLLTPSLSIFSSPYDILGTAQQKTPLSAVLDYSTSLTELEPFVPDSGILTASRHLPLYPPDTGIYFTPVPSEEVDAMWENINRSVTSLPSGATSEGSPVHLKLLGENSHAAAGATARSGDIYTRMSSRATEAVGVRTDPAPSVPWAIVAATVSAESALFSISLPFATFPGHSAAMSTYPDTVLNAGLFTQKFSSTAPNLPADSEIPSQSELDTELISPVPFTRSYSSCLYCDSVSLLPEAGFSPEHDVGSGDYVETLSFTASEVQGVTPFTTVITDKYELEEPTPEIFDTSFPSRPVVSFSSRFAEIHDSTLFLLSTVDTALDDRKPESSPSYHELPGETSLDISGFQFSLPVAGTVSLAPNTRVEDPATSTVLLETATIPSHLVASHAVSPTTWLESPELKPSESVFLFDKTSTREELSLNISDFSSNLLSTPFLIEPSYLLVSSAVLTSHSVMQSDFSTLLPQTSLTGTSLLSEDVSSWDLATAVSSATDSEVSLFSVGQISYFYSNASSVPGAPVPEIIPSSGFPSGSSVFLEASSVLPVGSEAMFTSAVSGATSQLEPSPSSLQYVAPTLVLPASDTGPLRSSVLLDETNLISVFTTFPTTPILNASSSLLSTGLASDEDIGATVKASLLLTSLSESSTHTTALLTADPDGPTQHADASSILPSPTESLSATTLFVPTQFPLTSLPPTGYDVPTGAGDADTSVAASTIPTTAATSTTGRSSVSSSPPLVTSTRPGATILPSATSTTRQPYVCDIAVPDVYLVTAVLARRAVLQNVSESIREVLRAQFRRSVELEVYKISPKFAFLVTSGPFVYTAIAVINVLVNSSLLRGSAPPILSLQPSFTVPDSRFQVQTVLQFVPRNMDIGFCNFSQRIEKGLTMAFMEVSKQHQEFYNFTVQILNITLSRPGAAFRQGPVSIIFAIRDRYGFLNGSEVSEQLRNLSVVEFSFYLGFPVQQIAEPFHYPKLNVSQLMKSSWVRTVLLGVVDQRIQEEVFQAEMERKLAHLLNEALARGRIWRRASFAGSNIVQIVNVSRLDGVDNPVELIYFVEDQDGERFSALKCSDLMNRVDIQRAAIILGYRIDGTVAQPVEKLKESSSEAQNSNLWIIVGVAVPVAVVLLIVIILYWKLCRTDKLEFQPDTISNIQQRQKLQAPSVKGFDFAKQHLGQHNKDDVLIIHEPAPLPGPIKDTTPSENGDVPSPKSKTSSKPSKTVRHRGRVSPSDADSTASEQSSGRETGEETARPSAVANEGKPRRATKKGPPQSSSGNEQHSSASIFEHVDRMSRSSDASRRVPSKIQLIAMQPMAAPPVQNSVLSDRVAETNKINKEIQTALRHKSEIEHHRNKIRLRAKRKGHYEFPVVDDVVVVDSKEQHRIYRKAQMQIDKILDPGGSVPTVFIEPRKSSRAKRSPKQRRRHQINGSPIDAEKDRLITTDSDGTYKRPPGVNNSAYISDPDLPPEPQTSSSADLGKFPGLPSHPVSQYVPPQPSIEEARQTMHSLLDDAFALVAPSSQAASSTAVTPPGVSAGQPRYVEFGMTPPAAPGLLPRQNFGPGFLQPAELMHPDQQPPEVQYSSRGIYSEEMPSMARPRPVGSTAGSQIQHLTQVGIASRIGGQQVEIPSGRAGHGQPGGPGWPQYRGEDEYARRDAMHMHGHQEYSSSPVFQMPRTSARQPSVPPAQLPHNNLQGQGLCYTTSSTEDLQPGHSSASLIKAIREELLRLSQKQTTVQNFHS", "length": 1871, "header": "tr|A0A8V0YCN2-1|A0A8V0YCN2_CHICK Computationally mapped isoform of KIAA1549 OS=Gallus gallus OX=9031 GN=KIAA1549 PE=4 SV=1 CANONICAL=A0A8V0YJ32-1" }, "locus": { "chromosome": "1", "start_pos": 56354133, "end_pos": 56233867, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031713.1", "url": "https://www.ensembl.org/id/ENSGALT00010031713.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018561.1", "url": "https://www.ensembl.org/id/ENSGALP00010018561.1" } ] } }, { "isoform_ac": "A0A8V0YJ32-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ32/entry#A0A8V0YJ32-1", "sequence": { "sequence": "MAGMTRFAARWRSALPALLPLLLAVPALRGSPAADEMSSEQRNFSFFSMDSKVHQSISGSRTQMALAESTLESQESHFLQTLLSSVTTPIDATSFNQEETARTSEGKSTPLIDFSVTSNEAFLSDDKFISPFPKVQWTPPLKSFAILTDHHSDNTVEAPRETLETPLLTPSLSIFSSPYDILGTAQQKTPLSAVLDYSTSLTELEPFVPDSGILTASRHLPLYPPDTGIYFTPVPSEEVDAMWENINRSVTSLPSGATSEGSPVHLKLLGENSHAAAGATARSGDIYTRMSSRATEAVGVRTDPAPSVPWAIVAATVSAESALFSISLPFATFPGHSAAMSTYPDTVLNAGLFTQKFSSTAPNLPADSEIPSQSELDTELISPVPFTRSYSSCLYCDSVSLLPEAGFSPEHDVGSGDYVETLSFTASEVQGVTPFTTVITDKYELEEPTPEIFDTSFPSRPVVSFSSRFAEIHDSTLFLLSTVDTALDDRKPESSPSYHELPGETSLDISGFQFSLPVAGTVSLAPNTRVEDPATSTVLLETATIPSHLVASHAVSPTTWLESPELKPSESVFLFDKTSTREELSLNISDFSSNLLSTPFLIEPSYLLVSSAVLTSHSVMQSDFSTLLPQTSLTGTSLLSEDVSSWDLATAVSSATDSEVSLFSVGQISYFYSNASSVPGAPVPEIIPSSGFPSGSSVFLEASSVLPVGSEAMFTSAVSGATSQLEPSPSSLQYVAPTLVLPASDTGPLRSSVLLDETNLISVFTTFPTTPILNASSSLLSTGLASDEDIGATVKASLLLTSLSESSTHTTALLTADPDGPTQHADASSILPSPTESLSATTLFVPTQFPLTSLPPTGYDVPTGAGDADTSVAASTIPTTAATSTTGRSSVSSSPPLVTSTRPGATILPSATSTTRQPYVCDIAVPDVYLVTAVLARRAVLQNVSESIREVLRAQFRRSVELEVYKISPKFAFLVTSGPFVYTAIAVINVLVNSSLLRGSAPPILSLQPSFTVPDSRFQVQTVLQFVPRNMDIGFCNFSQRIEKGLTMAFMEVSKQHQEFYNFTVQILNITLSRPGAAFRQGPVSIIFAIRDRYGFLNGSEVSEQLRNLSVVEFSFYLGFPVQQIAEPFHYPKLNVSQLMKSSWVRTVLLGVVDQRIQEEVFQAEMERKLAHLLNEALARGRIWRRASFAGSNIVQIVNVSRLDGVDNPVELIYFVEDQDGERFSALKCSDLMNRVDIQRAAIILGYRIDGTVAQPVEKLKESSSEAQNSNLWIIVGVAVPVAVVLLIVIILYWKLCRTDKLEFQPDTISNIQQRQKLQAPSVKGFDFAKQHLGQHNKDDVLIIHEPAPLPGPIKDTTPSENGDVPSPKSKTSSKPSKTVRHRGRVSPSDADSTASEQSSGRETGEETARPSAVANEGKPRRATKKGPPQSSSGNEQHSSASIFEHVDRMSRSSDASRRVPSKIQLIAMQPMAAPPVQNSVLSDRVAETNKINKEIQTALRHKSEIEHHRNKIRLRAKRKGHYEFPVVDDVVVVDSKEQHRIYRKAQMQIDKILDPGGSVPTVFIEPRKSSRAKRSPKQRRRHQINGSPIDAEKDRLITTDSDGTYKRPPGVNNSAYISDPDLPPEPQTSSSADLGKFPGLPSHPVSQYVPPQPSIEEARQTMHSLLDDAFALVAPSSQAASSTAVTPPGVSAGQPRYVEFGMTPPAAPGLLPRQNFGPGFLQPAELMHPDQQPPEVQYSSRGIYSEEMPSMARPRPVGSTAGSQIQHLTQVGIASRIGGQQVEIPSGRAGHGQPGGPGWPQYRGEDEYARRDAMHMHGHQEYSSSPVFQMPRTSARQPSVPPAQLPHNNLQGQGLCYTTSSTEDLQPGHSSASLIKAIREELLRLSQKQTTVQNFHS", "length": 1898, "header": "tr|A0A8V0YJ32-1|A0A8V0YJ32_CHICK Isoform 1 of KIAA1549 OS=Gallus gallus OX=9031 GN=KIAA1549 PE=4 SV=1 CANONICAL=A0A8V0YJ32-1" }, "locus": { "chromosome": "1", "start_pos": 56354133, "end_pos": 56218208, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031720.1", "url": "https://www.ensembl.org/id/ENSGALT00010031720.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018568.1", "url": "https://www.ensembl.org/id/ENSGALP00010018568.1" } ] } }, { "isoform_ac": "A0A8V0YL04-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ32/entry#A0A8V0YL04-1", "sequence": { "sequence": "MSSEQRNFSFFSMDSKVHQSISGSRTQMALAESTLESQESHFLQTLLSSVTTPIDATSFNQEETARTSEGKSTPLIDFSVTSNEAFLSDDKFISPFPKVQWTPPLKSFAILTDHHSDNTVEAPRETLETPLLTPSLSIFSSPYDILGTAQQKTPLSAVLDYSTSLTELEPFVPDSGILTASRHLPLYPPDTGIYFTPVPSEEVDAMWENINRSVTSLPSGATSEGSPVHLKLLGENSHAAAGATARSGDIYTRMSSRATEAVGVRTDPAPSVPWAIVAATVSAESALFSISLPFATFPGHSAAMSTYPDTVLNAGLFTQKFSSTAPNLPADSEIPSQSELDTELISPVPFTRSYSSCLYCDSVSLLPEAGFSPEHDVGSGDYVETLSFTASEVQGVTPFTTVITDKYELEEPTPEIFDTSFPSRPVVSFSSRFAEIHDSTLFLLSTVDTALDDRKPESSPSYHELPGETSLDISGFQFSLPVAGTVSLAPNTRVEDPATSTVLLETATIPSHLVASHAVSPTTWLESPELKPSESVFLFDKTSTREELSLNISDFSSNLLSTPFLIEPSYLLVSSAVLTSHSVMQSDFSTLLPQTSLTGTSLLSEDVSSWDLATAVSSATDSEVSLFSVGQISYFYSNASSVPGAPVPEIIPSSGFPSGSSVFLEASSVLPVGSEAMFTSAVSGATSQLEPSPSSLQYVAPTLVLPASDTGPLRSSVLLDETNLISVFTTFPTTPILNASSSLLSTGLASDEDIGATVKASLLLTSLSESSTHTTALLTADPDGPTQHADASSILPSPTESLSATTLFVPTQFPLTSLPPTGYDVPTGAGDADTSVAASTIPTTAATSTTGRSSVSSSPPLVTSTRPGATILPSATSTTRQPYVCDIAVPDVYLVTAVLARRAVLQNVSESIREVLRAQFRRSVELEVYKISPKFAFLVTSGPFVYTAIAVINVLVNSSLLRGSAPPILSLQPSFTVPDSRFQVQTVLQFVPRNMDIGFCNFSQRIEKGLTMAFMEVSKQHQEFYNFTVQILNITLSRPGAAFRQGPVSIIFAIRDRYGFLNGSEVSEQLRNLSVVEFSFYLGFPVQQIAEPFHYPKLNVSQLMKSSWVRTVLLGVVDQRIQEEVFQAEMERKLAHLLNEALARGRIWRRASFAGSNIVQIVNVSRLDGVDNPVELIYFVEDQDGERFSALKCSDLMNRVDIQRAAIILGYRIDGTVAQPVEKLKESSSEAQNSNLWIIVGVAVPVAVVLLIVIILYWKLCRTDKLEFQPDTISNIQQRQKLQAPSVKGFDFAKQHLGQHNKDDVLIIHEPAPLPGPIKDTTPSENGDVPSPKSKTSSKPSKTVRHRGRVSPSDADSTASEQSSGRETGEETARPSAVANEGKPRRATKKGPPQSSSGNEQHSSASIFEHVDRMSRSSDASRRVPSKIQLIAMQPMAAPPVQNSVLSDRVAETNKINKEIQTALRHKSEIEHHRNKIRLRAKRKGHYEFPVVDDVVVVDSKEQHRIYRKAQMQIDKILDPGGSVPTVFIEPRKSSRAKRSPKQRRRHQINGSPIDAEKDRLITTDSDGTYKRPPGVNNSAYISDPDLPPEPQTSSSADLGKFPGLPSHPVSQYVPPQPSIEEARQTMHSLLDDAFALVAPSSQAASSTAVTPPGVSAGQPRYVEFGMTPPAAPGLLPRQNFGPGFLQPAELMHPDQQPPEVQYSSRGIYSEEMPSMARPRPVGSTAGSQIQHLTQVGIASRIGGQQVEIPSGRAGHGQPGGPGWPQYRGEDEYARRDAMHMHGHQEYSSSPVFQMPRTSARQPSVPPAQLPHNNLQGQGLCYTTSSTEDLQPGHSSASLIKAIREELLRLSQKQTTVQNFHS", "length": 1862, "header": "tr|A0A8V0YL04-1|A0A8V0YL04_CHICK Computationally mapped isoform of KIAA1549 OS=Gallus gallus OX=9031 GN=KIAA1549 PE=4 SV=1 CANONICAL=A0A8V0YJ32-1" }, "locus": { "chromosome": "1", "start_pos": 56354133, "end_pos": 56284323, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031711.1", "url": "https://www.ensembl.org/id/ENSGALT00010031711.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018559.1", "url": "https://www.ensembl.org/id/ENSGALP00010018559.1" } ] } }, { "isoform_ac": "A0A8V0YL08-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ32/entry#A0A8V0YL08-1", "sequence": { "sequence": "MGYRKTYYCSCTDEMSSEQRNFSFFSMDSKVHQSISGSRTQMALAESTLESQESHFLQTLLSSVTTPIDATSFNQEETARTSEGKSTPLIDFSVTSNEAFLSDDKFISPFPKVQWTPPLKSFAILTDHHSDNTVEAPRETLETPLLTPSLSIFSSPYDILGTAQQKTPLSAVLDYSTSLTELEPFVPDSGILTASRHLPLYPPDTGIYFTPVPSEEVDAMWENINRSVTSLPSGATSEGSPVHLKLLGENSHAAAGATARSGDIYTRMSSRATEAVGVRTDPAPSVPWAIVAATVSAESALFSISLPFATFPGHSAAMSTYPDTVLNAGLFTQKFSSTAPNLPADSEIPSQSELDTELISPVPFTRSYSSCLYCDSVSLLPEAGFSPEHDVGSGDYVETLSFTASEVQGVTPFTTVITDKYELEEPTPEIFDTSFPSRPVVSFSSRFAEIHDSTLFLLSTVDTALDDRKPESSPSYHELPGETSLDISGFQFSLPVAGTVSLAPNTRVEDPATSTVLLETATIPSHLVASHAVSPTTWLESPELKPSESVFLFDKTSTREELSLNISDFSSNLLSTPFLIEPSYLLVSSAVLTSHSVMQSDFSTLLPQTSLTGTSLLSEDVSSWDLATAVSSATDSEVSLFSVGQISYFYSNASSVPGAPVPEIIPSSGFPSGSSVFLEASSVLPVGSEAMFTSAVSGATSQLEPSPSSLQYVAPTLVLPASDTGPLRSSVLLDETNLISVFTTFPTTPILNASSSLLSTGLASDEDIGATVKASLLLTSLSESSTHTTALLTADPDGPTQHADASSILPSPTESLSATTLFVPTQFPLTSLPPTGYDVPTGAGDADTSVAASTIPTTAATSTTGRSSVSSSPPLVTSTRPGATILPSATSTTRQPYVCDIAVPDVYLVTAVLARRAVLQNVSESIREVLRAQFRRSVELEVYKISPKFAFLVTSGPFVYTAIAVINVLVNSSLLRGSAPPILSLQPSFTVPDSRFQVQTVLQFVPRNMDIGFCNFSQRIEKGLTMAFMEVSKQHQEFYNFTVQILNITLSRPGAAFRQGPVSIIFAIRDRYGFLNGSEVSEQLRNLSVVEFSFYLGFPVQQIAEPFHYPKLNVSQLMKSSWVRTVLLGVVDQRIQEEVFQAEMERKLAHLLNEALARGRIWRRASFAGSNIVQIVNVSRLDGVDNPVELIYFVEDQDGERFSALKCSDLMNRVDIQRAAIILGYRIDGTVAQPVEKLKESSSEAQNSNLWIIVGVAVPVAVVLLIVIILYWKLCRTDKLEFQPDTISNIQQRQKLQAPSVKGFDFAKQHLGQHNKDDVLIIHEPAPLPGPIKDTTPSENGDVPSPKSKTSSKPSKTVRHRGRVSPSDADSTASEQSSGRETGEETARPSAVANEGKPRRATKKGPPQSSSGNEQHSSASIFEHVDRMSRSSDASRRVPSKIQLIAMQPMAAPPVQNSVLSDRVAETNKINKEIQTALRHKSEIEHHRNKIRLRAKRKGHYEFPVVDDVVVVDSKEQHRIYRKAQMQIDKILDPGGSVPTVFIEPRKSSRAKRSPKQRRRHQINGSPIDAEKDRLITTDSDGTYKRPPGVNNSAYISDPDLPPEPQTSSSADLGKFPGLPSHPVSQYVPPQPSIEEARQTMHSLLDDAFALVAPSSQAASSTAVTPPGVSAGQPRYVEFGMTPPAAPGLLPRQNFGPGFLQPAELMHPDQQPPEVQYSSRGIYSEEMPSMARPRPVGSTAGSQIQHLTQVGIASRIGGQQVEIPSGRAGHGQPGGPGWPQYRGEDEYARRDAMHMHGHQEYSSSPVFQMPRTSARQPSVPPAQLPHNNLQGQGLCYTTSSTEDLQPGHSSASLIKAIREELLRLSQKQTTVQNFHS", "length": 1876, "header": "tr|A0A8V0YL08-1|A0A8V0YL08_CHICK Computationally mapped isoform of KIAA1549 OS=Gallus gallus OX=9031 GN=KIAA1549 PE=4 SV=1 CANONICAL=A0A8V0YJ32-1" }, "locus": { "chromosome": "1", "start_pos": 56354133, "end_pos": 56232017, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031716.1", "url": "https://www.ensembl.org/id/ENSGALT00010031716.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018564.1", "url": "https://www.ensembl.org/id/ENSGALP00010018564.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1687, "start_aa": "Thr", "end_pos": 1687, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1687", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:100857885", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100857885", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D3Z9D0-1", "protein_name": "KIAA1549 homolog", "gene_name": "Kiaa1549", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEREPRAGVALVPGRCGRGPSSRHRRPGLLLPGLWLLLLAGPASCASDELSLEQHSHSLRPSEFQPETSIMHSAAQVTLSETVPRSQPSISVLVLSSPSPPSFDTAFLSQRQQTRSTVEHSIFEANYISVTSNEVALDEEEMDNFLPDAHWTSSRVVSPVRYITPSPLDPPQETLEPGSTPSLPTISLQDEVLSGCQNTVPQATVHVESTYFGTSWSAFLTSEGIVPTPSGNSVLHPTESHSQLSRKALPETVASVTEGAENLLFSSWISVSQPSGDGMTQQPSVPLWEVSQSLVGALATSTDRYPNETTAWSEHPEKAIALRAHPSETTSPTDPAFSSPPSDLFSTPLSSVSFATQLPGFSDNSFLSSEATEALESRYSSMVPSFTDHPLVLSPEASLRPHTRCVSCVVSLSQQELARSLTEKEMGSGDRLETLSTASVEATHLFPLSSVGTDPSELEDPQEFNTLFPSRPVVSFSSRPVGLWKASTDVSPEVDVSSIATTRVYPPHSRLSTLSSLDSTFGFSVTNDVVMSSGVTHLFSSVIPSTHFDSSFSLTGNQNTPSLPAGNPSLLTSYSLLPSAQSKVFSDGTPPSSLELESGLDFTSSFYSTPPLDFSTPAPSLSEVLAFPSLMSSDPSAFFSQPFSTVAETFSLSNSMDLQSPQLSVLNPTSLEPSQSRSSADLPLNTITVLPSHSEMPSLPSSLSESLKFTEASRVSLRESDVYVVTSAFSETTSAFEFSPIPHESTVSTLVPSSSEPTLGVSTTGIHLTSLTTVFHSTPMLTESPPFLTLAPSDGSVRETDHHMPVLTTPSSVIPASTESISDPYLSASSSLVSEVSSSPLPTKPVMDSSLTLTDLPPNTSPEPSTSQEPSMPNTSTAPGDTVDSALDSEPMSQNPQGNSVPPPQPSLGPVTTSTIEATVGTPALATAKPPYVCDITVPDVYLITTVLARRAVQEYIITSIKEVLRIHFNRAVELKVYELFTDFTFLVTSGPFVYTAISVINVLINSKLVRDQTPLILSVKPSFLVPDPRFQVQTVLQFVPPSVDTGFCNFTQSIEKGLVTALFEVRKHQGTYNLTVQIVNVTIASPRVAPRRGPVNIIFAVKGSKGFLNGSEVSDLLRNLTVVEFSFYLGYPVLQIAEPFQYPQLNLSHLLKSSWVRTVLLGVVEKQLHNEVFPAEMERKLAQLLSEVPTRRRMWRRATVAAGNSVVQVVNVSRLEGEDNPVQLIYFVENQDGERLSAARSSDLINKVDLQRAAIILGYRIQGAIAQPVDRVKRPSPESQSSNLWVVVGVVIPVLVVTVIVVILYWKLCRTDKLDFQPDTVANIQQRQKLQIPSVKGFDFAKQHLGQHNKDDILIIHEPAPLPGPVKDHTTPSENGDVPSPKSKMPSKNLRHRGRVSPSDADSTVSEESSERDVGEKTTATAPENKAHRAPQSGAPLPSSTNEQHSSASIFEHVDRISRTSEASRRVPSKIQLIAMQPIPAPPVPHPVLADRVAETNKINKEIQSALRHKSEIEHHRNKIRLRAKRRGHYEFPVVDDLSSGDTKERHRVYRRAQMQIDKILDPAASVPSVFIEPRKSSRMKRSPKPRRKHQVNGCPADAEKDRLITTDSDGTYKRPPGVHNSAYIGCPSDPDLPADVQTPSSAELGRYPGLPFSASQYIPPQPSIEEARQTMHSLLDDAFALVAPSSQPTNAMGVGTGVPASLPVNSTPSREERRATQWGSFYSPAQTANNPCSRYEDYGMTPPSGPLPSRPSFGPGLLPSSELVPPEPPQPQSSSDTPYAARGIYSEEMPSVARPRPVGGTTGSQIQHLTQVGIASRIGAQPVEIPPGRGSQYGGPGWPVYGEEEAGRREATHMLGHQEYSSSPLFQVPRTSGREPSAPPGNLAHRGLQGPGLGYPTSSTEDLQPGHSSASLIKAIREELLRLSQKQGSVQNFHS", "length": 1937 }, "evidence": [ { "id": "A0A8V0YJ32", "url": "https://omabrowser.org/oma/group/A0A8V0YJ32/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1SR15-1", "protein_name": "KIAA1549", "gene_name": "KIAA1549", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MLKESIMHSTAHVALTETTPGSQQSRSLQVRPSPSATTFDTAFFNQGQWTQSTAEHSVFLANYVSVTSNEVTEDEDMDNFLPETPWTTSREVSPARYITVRPPGPPRDMSDPMPTPSLPIIAFQDEEVTSAWQNTVQQPATSAGSPGRFSAFPSALPTSKGIIAAPSGSWVFYPTDAYGHVSSRTLPEITSSGVEGAETLLLGLPSSEPQTPGDGVTKQPPRPSGEVLPPPEDALATGRDRFPDVTADWGQSLDETISPKTYRPAGVSPVVLAFSSSTHLALFSTPLAFGPFSTQSADNPFLPSNSGEVSELPGRSLVPGHEADTHIRSLVSLFSPHTWCTSCTMVSPQYELSASLTEDVGSGDGAETLSLTLLEASSISPRSSIMADVPEFEEDAPAFNTLFPSRPIVPLSSPSVEISATGVAVSVERRMSSVLTSQVYSPHGHLPGSGSLDPAPAGSPSIAESHVMPSGVTAVVSSVSPRLPLDSSFRITANRNTPSPDVRGPGLFTSYGLDPSVDSSPFPAQGPASFSRHESARISDFASSVFSTPPLESSSWVPPSPTSRAKSTFSPQAFSALVETLTLTSSVNSPLPQLSVPNSTHLDLSQLRPSSELLLNTFTLLPASSEVSPRSSVPSESLKVLEASTVSQTDSEAPFTSAFTESTSSFEFSHTSRTSAVAPLVPSSPEPILPSETHFTPLWTAVQTTPALTESSLVSTLTPSEGDISAVQDHTSVPASSSEVIPTPTLPVTAGYPTPASSFVPELSPSPLPTEPDPLHGPSFVPTDVPRNTSTELIVSDTSVAPGNSVDTTPNSRTSSQNPHEGSTALPPPSLHPVTAPVPESEVHTPALLTTKPPYVCDISVPDAYLITTVLARRAVQEYIITSIKEVLKSHFNRVVELKVYELFADFTFLVTSGPFVYTAISVINVLINSKLVRDQTPLILAVKPSFLVPDSRFQVQTVLQFVPQSVDTGFCNFTQRIEKGLMVALSEVRKHHQGAYNLTVQILNITVGSSRLAPRRGPVNIVFAIKGVQGFLNGSEVSELLRNLSVVEFSFYLGYPVLQIAEPFQYPQLNLSQLLKSSWVRTVLLGVVEKQLQNEVFQAEMERKLAQLLSEVSTRRRMWRRATVAAGNSMVQVVNVSRLEGDDNPVQLIYFVEDQDGERLSAVKSSDLINRIDIQRAAIILGYRIQGAVAQPVDRVKRPEPESQSSNLWVIVGVVIPGLLVALIVVILYWKLCRTDKLDFQPDTVANIQQRQKLQIPSVKGFDFAKQHLGQHNKDDILIIHEPAPLPGPMKDHTTPSENGDVPSPKAKIPSKNIRHRGRVSPSDADSTVSEESSEREAGDKTPGAVTDGAPPSSGNEQHSSASIFEHVDRISRSSEASRRVPSKIQLIAMQPIPAPPVPHPILADRVAETNKINKEIQTALRHKSEIEHHRNKIRLRAKRRGHYEFPVVDDLSSGDTRERHRVYRRAQMQIDKILDPTASVPSVFIEPRKSSRIKRSPKPRRKHQVNGCPGDAERDRLITTDSDGTYKRPPGVHNSAYMGCPSDPDLPAEVQTPSSAELGRYPGLPFPASQYVPPQPSIEEARQTMHSLLDDAFALVAPSSQPPNAAAAGPGLPAGLPVNSTPSGEERRTTQWGSFYSPAQTANNPCSRYEDYGMTPPLGPLSRPGFGPGLLPSAELVPPEAHQPQASSEVTSFAARGIYSEEGPSVARPRPVGGTTGSQIQHLTQVGIASRIGAQPVEIPPGRGGQYGGPGWPSYGEDEAGRREATHVLGHQEYSSSPLFQAPRTSGREPSAPPGNLPPRGLPGAGLAYPASSTEDLQPGHSSASLIKAIREELLRLSQKQSAVQNFYS", "length": 1851 }, "evidence": [ { "id": "A0A8V0YJ32", "url": "https://omabrowser.org/oma/group/A0A8V0YJ32/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q68FD9-1", "protein_name": "UPF0606 protein KIAA1549", "gene_name": "Kiaa1549", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEREPRARVALVPERCGRGPSSRHRRPGLLLPGLWLLLLAGPASCAPDDLSLAQHSHPVRPSDFLPERSILHSAAQVTLSETVPRSQPSISALVLSSPSATAFDTAFLSQRQQTQSTAEPSFFEANYGSVTSNEVALDDEEMDNFLPDAHWTSSRGVSPMRYITPSPPEPPQEMLEPGTTPSLPTISLPDEVLSGCQNTVQQATVYVEPSTYFGTSWSAFLTSEGIIPTPSRNSVLHPIEIHSQLSSKALPETVASVTEGAENLLFSSRISVSQPSGNGMTQQPSVPLWEVSQPLVGVLATSSDRYPNETTAWIEHPEEAIALRAHPGITTSPTDPTFSSQPSALFSTPLSSVSFATQLPGVSEDSFLSSEARGALESWHSSPVPSFTDHPYVLSPESSLRPHTGCVSCVVSSFQQELARSLTEKDMGSGDRLETLSTASVEASHVSPLSSVGTDLSELEEPQEFNTLFPSRPVFSFSSRPVGLWKASMDVSPEVDVSGIAITQVYPSHGRLSTPSSLDSTFGFSVTSDLVMSSSMIHLLSSVIPSTHFDSSFSLTANQNSPSFPAGKPSLLTSPSLVPSAQSSAFSHGAPTSSLELQSGSRLDFTSGFYSTPPLDFSTPAPSRSDELAFPSLMSSDPSTFFSQTFSTMAETFSLSNSMNLQSPQLSVLNPTSLEPSQPQSSADLLLNTVTVLPSPPERPPLSSSPSDSLEFTEVSRVSLRESHVHLTSAFSETTSAFEFSPIPHESTISTLVPSSSEPSLGIYAAGTHLTSLPTTVFHLTPILTESSPFSTLTPSDGSVRVTDHHTPVLPTPSSVIPSSTESISDPYLSASSSLVSEVSPSPPPTKPVMGSSLTSTDFPPSTSPELSTSLELSMPSASTAPGDTVDSALNSEPMSQNPQGNSVPPPQPSLGPATTSTLEATVGTPALATAKPPYVCDITVPDVYLITTVLARRAVQEYIITSIKEVLRIHFNRAVELKVYELFTDFTFLVTSGPFVYTAISVINVLINSKLVRGQTPLILSVKPSFLVPDPRFQVQTVLQFVPPSVDTGFCNFTQSIEKGLVTALFEVRKHQGTYNLTVQIVNVTIASSRVAPRRGPVNIIFAVKGSQGFLNGSEVSDLLRNLTVVEFSFYLGYPVLQIAEPFQYPQLNLSQLLKSSWVRTVLLGVVEKQLHNEVFPAEMERKLAQLLSEVPTRRRVWRRATVAAGNSVVQVVNVSRLEGDDNPVQLIYFVENQDGERLSAVKSSDLINKVDLQRAAIILGYRIQGVIAQPVDRVKRPSPESQSNNLWVVVGVVIPVLVVTVIVVILYWKLCRTDKLDFQPDTVANIQQRQKLQIPSVKGFDFAKQHLGQHNKDDILIIHEPAPLPGPVKDHTTPSENGDVPSPKSKLPSKNIRLRGRVSPSDADSTVSEESSERDAGEKAPAAAPENKALRAPQSGAPLPSSGNEQHSSASIFEHVDRVSRTSEASRRVPSKIQLIAMQPIPAPPAQHPVLADRVAETNKINKEIQSALRHKSEIEHHRNKIRLRAKRRGHYEFPVVDDLSSGDTKERHRVYRRAQMQIDKILDPAASVPSVFIEPRKSSRMKRSPKPRRKHQVNGCPADAEKDRLITTDSDGTYKRPPGVHNSAYIGCPSDPDLPADVQTPSSTELGRYPGLPFSASQYIPPQPSIEEARQTMHSLLDDAFALVAPSSQPTNAMGAGTGVPASLPVNSTPSREERRATQWGSFYSPAQTANNPCSRYEDYGMTPPSGPLPSRPSFGPGLLPSSELVPPEPPQPQSSTDAPYAARGIYSEEMPSVARPRPVGGTTGSQIQHLTQVGIASRIGAQPVEIPAGRGSQYGGPGWPVYGEEEAGRREATHMLGHQEYSSSPLFQVPRTSGREPSAPPGNLAHRGLQGPGLGYPTSSTEDLQPGHSSASLIKAIREELLRLSQKQGSVQNFHS", "length": 1940 }, "evidence": [ { "id": "A0A8V0YJ32", "url": "https://omabrowser.org/oma/group/A0A8V0YJ32/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9HCM3-1", "protein_name": "UPF0606 protein KIAA1549", "gene_name": "KIAA1549", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPGARRRRRGAAMEGKPRAGVALAPGPSGRRPSARCARRRRPGLLLPGLWLLLLARPASCAPDELSPEQHNLSLYSMELVLKKSTGHSAAQVALTETAPGSQHSSPLHVTAPPSATTFDTAFFNQGKQTKSTADPSIFVATYVSVTSKEVAVNDDEMDNFLPDTHWTTPRMVSPIQYITVSPPGLPREALEPMLTPSLPMVSLQDEEVTSGWQNTTRQPAAYAESASHFHTFRSAFRTSEGIVPTPGRNLVLYPTDAYSHLSSRTLPEIVASLTEGVETTLFLSSRSLMPQPLGDGITIPLPSLGEVSQPPEEVWATSADRYTDVTTVLSQSLEETISPRTYPTVTASHAALAFSRTHSPLLSTPLAFASSASPTDVSSNPFLPSDSSKTSELHSNSALPGPVDNTHILSPVSSFRPYTWCAACTVPSPQQVLATSLMEKDVGSGDGAETLCMTVLEESSISLMSSVVADFSEFEEDPQVFNTLFPSRPIVPLSSRSMEISETSVGISAEVDMSSVTTTQVPPAHGRLSVPASLDPTAGSLSVAETQVTPSSVTTAFFSVITSILLDSSFSVIANKNTPSLAVRDPSVFTPYSLVPSVESSLFSDQERSSFSEHKPRGALDFASSFFSTPPLELSGSISSPSEAPASLSLMPSDLSPFTSQSFSPLVETFTLFDSSDLQSSQLSLPSSTNLEFSQLQPSSELPLNTIMLLPSRSEVSPWSSFPSDSLEFVEASTVSLTDSEAHFTSAFIETTSYLESSLISHESAVTALVPPGSESFDILTAGIQATSPLTTVHTTPILTESSLFSTLTPPDDQISALDGHVSVLASFSKAIPTGTVLITDAYLPSGSSFVSEATPFPLPTELTVVGPSLTPTEVPLNTSTEVSTTSTGAATGGPLDSTLMGDAASQSPPESSAAPPLPSLRPVTAFTLEATVDTPTLATAKPPYVCDITVPDAYLITTVLARRAVQEYIITAIKEVLRIHFNRAVELKVYELFTDFTFLVTSGPFVYTAISVINVLINSKLVRDQTPLILSVKPSFLVPESRFQVQTVLQFVPPSVDTGFCNFTQRIEKGLMTALFEVRKHHQGTYNLTVQILNITISSSRVTPRRGPVNIIFAVKSTQGFLNGSEVSELLRNLSVVEFSFYLGYPVLQIAEPFQYPQLNLSQLLKSSWVRTVLLGVMEKQLQNEVFQAEMERKLAQLLSEVSTRRRMWRRATVAAGNSVVQVVNVSRLEGDDNPVQLIYFVEDQDGERLSAVKSSDLINKMDLQRAAIILGYRIQGVIAQPVDRVKRPSPESQSNNLWVIVGVVIPVLVVMVIVVILYWKLCRTDKLDFQPDTVANIQQRQKLQIPSVKGFDFAKQHLGQHNKDDILIIHEPAPLPGPLKDHTTPSENGDVPSPKSKIPSKNVRHRGRVSPSDADSTVSEESSERDAGDKTPGAVNDGRSHRAPQSGPPLPSSGNEQHSSASIFEHVDRISRPPEASRRVPSKIQLIAMQPIPAPPVQRPSPADRVAESNKINKEIQTALRHKSEIEHHRNKIRLRAKRRGHYEFPVVDDLSSGDTKERHRVYRRAQMQIDKILDPTASVPSVFIEPRKSSRIKRSPKPRRKHQVNGCPADAEKDRLITTDSDGTYRRPPGVHNSAYIGCPSDPDLPADVQTPSSVELGRYPALPFPASQYIPPQPSIEEARQTMHSLLDDAFALVAPSSQPASTAGVGPGVPPGLPANSTPSQEERRATQWGSFYSPAQTANNPCSRYEDYGMTPPTGPLPRPGFGPGLLQSTELVPPDPQQPQASAEAPFAARGIYSEEMPSVARPRPVGGTTGSQIQHLTQVGIASRIGAQPVEIPPSRGSQYGGPGWPSYGEDEAGRREATHMLGHQEYSSSPLFQVPRTSGREPSAPSGNLPHRGLQGPGLGYPTSSTEDLQPGHSSASLIKAIREELLRLSQKQSTVQNFHS", "length": 1950 }, "evidence": [ { "id": "A0A8V0YJ32", "url": "https://omabrowser.org/oma/group/A0A8V0YJ32/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 1037, "end_pos": 1039, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1062, "end_pos": 1064, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1069, "end_pos": 1071, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1098, "end_pos": 1100, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1108, "end_pos": 1110, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1135, "end_pos": 1137, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1199, "end_pos": 1201, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1586, "end_pos": 1588, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1613, "end_pos": 1615, "annotation": "n_glycosylation_sequon" }, { "start_pos": 247, "end_pos": 249, "annotation": "n_glycosylation_sequon" }, { "start_pos": 43, "end_pos": 45, "annotation": "n_glycosylation_sequon" }, { "start_pos": 587, "end_pos": 589, "annotation": "n_glycosylation_sequon" }, { "start_pos": 674, "end_pos": 676, "annotation": "n_glycosylation_sequon" }, { "start_pos": 774, "end_pos": 776, "annotation": "n_glycosylation_sequon" }, { "start_pos": 943, "end_pos": 945, "annotation": "n_glycosylation_sequon" }, { "start_pos": 993, "end_pos": 995, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 1687 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1037, "end_pos": 1039 }, { "start_pos": 1062, "end_pos": 1064 }, { "start_pos": 1069, "end_pos": 1071 }, { "start_pos": 1098, "end_pos": 1100 }, { "start_pos": 1108, "end_pos": 1110 }, { "start_pos": 1135, "end_pos": 1137 }, { "start_pos": 1199, "end_pos": 1201 }, { "start_pos": 1586, "end_pos": 1588 }, { "start_pos": 1613, "end_pos": 1615 }, { "start_pos": 247, "end_pos": 249 }, { "start_pos": 43, "end_pos": 45 }, { "start_pos": 587, "end_pos": 589 }, { "start_pos": 674, "end_pos": 676 }, { "start_pos": 774, "end_pos": 776 }, { "start_pos": 943, "end_pos": 945 }, { "start_pos": 993, "end_pos": 995 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YJ42-1", "uniprot_ac": "A0A8V0YJ42", "uniprot_id": "A0A8V0YJ42_CHICK", "mass": { "chemical_mass": 98218.0, "monoisotopic_mass": 98218.0 }, "refseq": { "ac": "XP_040513312", "name": "transforming growth factor-beta receptor-associated protein 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040513312" }, "gene_names": [ { "name": "TGFBRAP1", "type": "recommended", "evidence": [ { "id": "A0A8V0YJ42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ42" } ] }, { "name": "TGFBRAP1", "type": "synonym", "evidence": [ { "id": "XP_040513312", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040513312" } ] } ], "protein_names": [ { "name": "Transforming growth factor beta receptor associated protein 1", "type": "synonym", "evidence": [ { "id": "A0A8V0YJ42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ42/entry#names_and_taxonomy" } ] }, { "name": "transforming growth factor-beta receptor-associated protein 1", "type": "synonym", "evidence": [ { "id": "XP_040513312", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040513312" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040513312", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040513312" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJ42", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ42" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TGFBRAP1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ42", "locus": { "chromosome": "1", "start_pos": 135207970, "end_pos": 135238405, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013217", "url": "https://www.ensembl.org/id/ENSGALG00010013217" } ] } } ], "crossref": [ { "id": "A0A8V0YJ42", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YJ42", "database": "AlphaFoldDB", "categories": [] }, { "id": "418724", "url": "https://www.ncbi.nlm.nih.gov/gene/418724", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000547", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000547", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001180", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001180", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019453", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019453", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032914", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032914", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:418724", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418724", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MFVTSEG", "url": "https://omabrowser.org/oma/group/MFVTSEG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YJ42", "url": "https://www.orthodb.org/?gene=A0A8V0YJ42", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12894", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12894", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12894:SF27", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12894:SF27", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00780", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00780", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF10366", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10366", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF10367", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10367", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_040513312", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040513312", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YJ42", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ42", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJ42-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ42-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSVKAFKLVSAVEREMLMGDKNHINIECIECCGKNLYIGTNDCFIYHFMLDEKVSTSGKITFAATKQLHKYLGFKKPVSELKAASALTRLLVLCDNTITLVNMMNLEPVPSGARIKGAVTFTLNENPVSGDPFCVEVCIISVKRRTIQMFMVFEDRVQIVKEVVTPEQPCAVAVDGYYLCLALTTQYIILNYNTGISQDLFPYCSDEKRPIVKRIGRQEFLLAGPGGLGMFATVDGISQRAPVHWSENVIGAALCFPYVVALDEEFITVHSMLDQQQKQTLPFKEGHILQDFEGKVIVATNKGVYILVPLPLEKQIQDLLASHRVEEALVLAKGARRNIPKEKFQVMYKRILQQAGFIQFAQLQFLEAKELFRSGQLDVRELISLYPFLLPTSSSFIRSHPPLHEYADLNQLTQGDQEKMIKCKQFLMSYLNEVRSTEVANGYKEDIDTALLKLYAEANHESLLDLLVSENFCLLTDSAAWLEKHKKYFALGLLYHYNGQDAAALQLWVQIVDGDIEDSTRSDLYEYVVDFLTFCSDQDLVWKYSEWVLQKNEEVGVQIFTKRPLEEQEKNNMNPDDVISCLNKYPKARIKYLEHLVLERKIEKEKYHTHLAALYLEAILQLKSGTTDNCMETIELLLKLRSLLQKSDLYRIHFILDKIRGTDLHMESAILYGKLEEHEKALHILVHELKDFRAAEEYCIWNSENRDLQYRRRLFHMLLSVYLNPDSSDCALVMAAVDLLNNHAAEFDAALVLQLVPDSWSVQLLSPFLAGAVRQSIHTKRMTQVALGLAQAENLIYKYEKVKHKGAPILLSDKKVCQVCQNPFCEPAFVRYPNGGVVHTHCAANRHQNSNVTPHSSSSSSET", "length": 863, "header": "tr|A0A8V0YJ42-1|A0A8V0YJ42_CHICK Isoform 1 of Transforming growth factor beta receptor associated protein 1 OS=Gallus gallus OX=9031 GN=TGFBRAP1 PE=1 SV=1 CANONICAL=A0A8V0YJ42-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YJ42-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ42/entry#A0A8V0YJ42-1", "sequence": { "sequence": "MSVKAFKLVSAVEREMLMGDKNHINIECIECCGKNLYIGTNDCFIYHFMLDEKVSTSGKITFAATKQLHKYLGFKKPVSELKAASALTRLLVLCDNTITLVNMMNLEPVPSGARIKGAVTFTLNENPVSGDPFCVEVCIISVKRRTIQMFMVFEDRVQIVKEVVTPEQPCAVAVDGYYLCLALTTQYIILNYNTGISQDLFPYCSDEKRPIVKRIGRQEFLLAGPGGLGMFATVDGISQRAPVHWSENVIGAALCFPYVVALDEEFITVHSMLDQQQKQTLPFKEGHILQDFEGKVIVATNKGVYILVPLPLEKQIQDLLASHRVEEALVLAKGARRNIPKEKFQVMYKRILQQAGFIQFAQLQFLEAKELFRSGQLDVRELISLYPFLLPTSSSFIRSHPPLHEYADLNQLTQGDQEKMIKCKQFLMSYLNEVRSTEVANGYKEDIDTALLKLYAEANHESLLDLLVSENFCLLTDSAAWLEKHKKYFALGLLYHYNGQDAAALQLWVQIVDGDIEDSTRSDLYEYVVDFLTFCSDQDLVWKYSEWVLQKNEEVGVQIFTKRPLEEQEKNNMNPDDVISCLNKYPKARIKYLEHLVLERKIEKEKYHTHLAALYLEAILQLKSGTTDNCMETIELLLKLRSLLQKSDLYRIHFILDKIRGTDLHMESAILYGKLEEHEKALHILVHELKDFRAAEEYCIWNSENRDLQYRRRLFHMLLSVYLNPDSSDCALVMAAVDLLNNHAAEFDAALVLQLVPDSWSVQLLSPFLAGAVRQSIHTKRMTQVALGLAQAENLIYKYEKVKHKGAPILLSDKKVCQVCQNPFCEPAFVRYPNGGVVHTHCAANRHQNSNVTPHSSSSSSET", "length": 863, "header": "tr|A0A8V0YJ42-1|A0A8V0YJ42_CHICK Isoform 1 of Transforming growth factor beta receptor associated protein 1 OS=Gallus gallus OX=9031 GN=TGFBRAP1 PE=1 SV=1 CANONICAL=A0A8V0YJ42-1" }, "locus": { "chromosome": "1", "start_pos": 135235283, "end_pos": 135208819, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031738.1", "url": "https://www.ensembl.org/id/ENSGALT00010031738.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018578.1", "url": "https://www.ensembl.org/id/ENSGALP00010018578.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:418724", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418724", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2JV19-1", "protein_name": "Transforming growth factor, beta receptor associated protein 1", "gene_name": "Tgfbrap1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSGNVVPSPCSTTCLCGFLDPPFKLRLQTLHLQKVVTANLKIESLNWGAFQQEHFMPDYAVDMMNIKAFTLVSAVERELLMGDRDHISIECVECCGRNLYVGTNDCFIYHFLLEEKAMPTGTATFIATKQLHRHLGFKKPVNELCAASALNRLLVLCDNSITLVNMLNLEPVPSGARIKGATTFAVNENPVNGDPFCVEVCIISVKRRTVQMFLVYEDRVQIVKEVSTTEQPLAVAVDGYFLCLALTTQYIILNYSTGFSQDLFPYCSEEKPPIVKRIGRQEFLLAGPGGLGMFATVAGISQRAPVHWSENVIGAAVCFPYVIALDDEFITVHSMLDQQQKQTLPFKEGHILQDFEGRVIVATSKGVYILVPLPLEKQIQDLLANRRVEEALVLAKGARRNIPKEKFQVMYRRILQQAGFIQFAQLQFLEAKELFRSSQLDVRELISLYPFLLPTSSSFTRSHPPLHEYADLNQLTQGDQEKMAKCKRFLMSYLNEIRSTEVANGYKEDIDTALLKLYAEADHDSLLDLLVTENSCLLTDSAAWLEKHKKYFALGLLYHYNKQDASAVQLWVNIVNGDIQDSTRSDLYEYIVDFLTYCLDQELVWTHADWLLQKSQEVGVQVFTKRPLDEQQQTSFNPDDIISCLKKYPKALVKYLEHLVIDRRLQKEEYHTHLALLYLEEVLRQRAPTGGKDVEATETQAKLRRLLQKSDLYRVHLLKEKIQGAGLPMESAILHGKLGEHEKALHILVHEMGDFSAAEDYCLWSSEGQDAACRQRLFHTLLAMYLRAGPSAHDLTVAAVDLLNHHAREFDATQVLQLLPDTWSVQLLCPFLTGAMRDSIHARRTTQVALGLAKSENLIYMYDKMKLKGSAIWLSEKKLCQLCQNPFGEPVFVRYPNGGLVHTHCAASRHTNPSSPSPGTRT", "length": 922 }, "evidence": [ { "id": "A0A8V0YJ42", "url": "https://omabrowser.org/oma/group/A0A8V0YJ42/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A286ZTX8-1", "protein_name": "Transforming growth factor beta receptor associated protein 1", "gene_name": "TGFBRAP1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": 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"glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8C2LAI4-1", "protein_name": "Transforming growth factor-beta receptor-associated protein 1", "gene_name": "Tgfbrap1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": 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"glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q3UR70-1", "protein_name": "Transforming growth factor-beta receptor-associated protein 1", "gene_name": "Tgfbrap1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": 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"glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8WUH2-1", "protein_name": "Transforming growth factor-beta receptor-associated protein 1", "gene_name": "TGFBRAP1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": 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"glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJ42", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ42" } ], "pmid": "" }, { "name": "early endosome", "id": "GO:0005769", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005769", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJ42", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ42" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJ42", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ42" } ], "pmid": "" }, { "name": "CORVET complex", "id": "GO:0033263", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033263", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJ42", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ42" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "intracellular protein transport", "id": "GO:0006886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJ42", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ42" } ], "pmid": "" }, { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJ42", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ42" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJ42", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ42" } ], "pmid": "" }, { "name": "endosome to lysosome transport", "id": "GO:0008333", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008333", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJ42", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ42" } ], "pmid": "" }, { "name": "endosomal vesicle fusion", "id": "GO:0034058", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034058", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJ42", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ42" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "transforming growth factor beta receptor binding", "id": "GO:0005160", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005160", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJ42", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ42" } ], "pmid": "" }, { "name": "SMAD binding", "id": "GO:0046332", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046332", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJ42", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ42" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 851, "end_pos": 853, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YJ42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ42" }, { "id": "PS50219", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50219" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CNH", "eco_id": "ECO_0000259", "start_pos": 23, "end_pos": 296, "start_aa": "His", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], 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"sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YLS1-1", "uniprot_ac": "A0A8V0YLS1", "uniprot_id": "A0A8V0YLS1_CHICK", "mass": { "chemical_mass": 36172.0, "monoisotopic_mass": 36172.0 }, "refseq": { "ac": "XP_416460", "name": "gamma-parvin", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_416460" }, "gene_names": [ { "name": "PARVG", "type": "recommended", "evidence": [ { "id": "A0A8V0YLS1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLS1" } ] }, { "name": "PARVG", "type": "synonym", "evidence": [ { "id": "XP_416460", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_416460" } ] } ], "protein_names": [ { "name": "Gamma-parvin", "type": "recommended", "evidence": [ { "id": "A0A8V0YLS1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLS1/entry#names_and_taxonomy" } ] }, { "name": "gamma-parvin", "type": "synonym", "evidence": [ { "id": "XP_416460", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_416460" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_416460.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_416460", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_416460" } ] }, { "annotation": "Plays a role with ILK in promoting the cell adhesion and spreading of leukocytes.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLS1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLS1#function" }, { "database": "UniProtKB", "id": "ARBA00057182", "url": "https://www.uniprot.org/uniprotkb/ARBA00057182#function" }, { "database": "UniProtKB", "id": "A0A8V0YRR5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRR5#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLS1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLS1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PARVG", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLS1", "locus": { "chromosome": "1", "start_pos": 69280548, "end_pos": 69259275, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013324", "url": "https://www.ensembl.org/id/ENSGALG00010013324" } ] } } ], "crossref": [ { "id": "A0A8V0YLS1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YLS1", "database": "AlphaFoldDB", "categories": [] }, { "id": "418236", "url": "https://www.ncbi.nlm.nih.gov/gene/418236", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001715", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001715", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028433", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028433", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036872", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036872", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "SEHIVVQ", "url": "https://omabrowser.org/oma/group/SEHIVVQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YJ66", "url": "https://www.orthodb.org/?gene=A0A8V0YJ66", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YLS1", "url": "https://www.orthodb.org/?gene=A0A8V0YLS1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YRR5", "url": "https://www.orthodb.org/?gene=A0A8V0YRR5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12114", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12114", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12114:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12114:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00307", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00307", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_416460", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_416460", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YJ66", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ66", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJ66-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ66-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLS1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLS1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLS1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLS1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YRR5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRR5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YRR5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRR5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDADFLNAFTQPAAVNQFLVENVITPGEKRKLIKPTSSNNPKLEQLKLLLIDWINTTLKEEHIVVKSLEEDLYDGLVLHHLLENLGSLKLDVDKIALTEKKQRQKLSVILEAVAKCLQLEESQLKWSVEAILAKDLLSTLHLLVAIAKHFQPSLAFPPNVHVETITIENTSKGLKTANGVEYITGSKENSEEQSTDDAFDELFSRAPERLDDVKKVFLQFVNQHVGKLGLNVKDMESQFADGVILLLLIGHLEGYFLNLRDFFLTPASTTEMLHNVNLALDLLTDGGLLNFSVNSEDIVKGDLKTTMRVLYCLYSKYKAKET", "length": 322, "header": "tr|A0A8V0YLS1-1|A0A8V0YLS1_CHICK Isoform 1 of Gamma-parvin OS=Gallus gallus OX=9031 GN=PARVG PE=3 SV=1 CANONICAL=A0A8V0YLS1-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YJ66-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLS1/entry#A0A8V0YJ66-1", "sequence": { "sequence": "MDADFLNAFTQPAAVNQFLVENVITPGEKRKLIKPTSSNNPKLEQLKLLLIDWINTTLKEEHIVVKSLEEDLYDGLVLHHLLENLGSLKLDVDKIALTEKKQRQKLSVILEAVAKCLQLEESQLKWSVEAILAKDLLSTLHLLVAIAKHFQPSLAFPPNVHVETITIENTSKGLKTANGVEYITGSKENSEEQSTDDAFDELFSRAPERLDDVKKFADGVILLLLIGHLEGYFLNLRDFFLTPASTTEMLHNVNLALDLLTDGGLLNFSVNSEDIVKGDLKTTMRVLYCLYSKYKAKET", "length": 299, "header": "tr|A0A8V0YJ66-1|A0A8V0YLS1_CHICK Computationally mapped isoform of Gamma-parvin OS=Gallus gallus OX=9031 GN=PARVG PE=3 SV=1 CANONICAL=A0A8V0YLS1-1" }, "locus": { "chromosome": "1", "start_pos": 69279347, "end_pos": 69263965, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032070.1", "url": "https://www.ensembl.org/id/ENSGALT00010032070.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018860.1", "url": "https://www.ensembl.org/id/ENSGALP00010018860.1" } ] } }, { "isoform_ac": "A0A8V0YLS1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLS1/entry#A0A8V0YLS1-1", "sequence": { "sequence": "MDADFLNAFTQPAAVNQFLVENVITPGEKRKLIKPTSSNNPKLEQLKLLLIDWINTTLKEEHIVVKSLEEDLYDGLVLHHLLENLGSLKLDVDKIALTEKKQRQKLSVILEAVAKCLQLEESQLKWSVEAILAKDLLSTLHLLVAIAKHFQPSLAFPPNVHVETITIENTSKGLKTANGVEYITGSKENSEEQSTDDAFDELFSRAPERLDDVKKVFLQFVNQHVGKLGLNVKDMESQFADGVILLLLIGHLEGYFLNLRDFFLTPASTTEMLHNVNLALDLLTDGGLLNFSVNSEDIVKGDLKTTMRVLYCLYSKYKAKET", "length": 322, "header": "tr|A0A8V0YLS1-1|A0A8V0YLS1_CHICK Isoform 1 of Gamma-parvin OS=Gallus gallus OX=9031 GN=PARVG PE=3 SV=1 CANONICAL=A0A8V0YLS1-1" }, "locus": { "chromosome": "1", "start_pos": 69279347, "end_pos": 69263965, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032059.1", "url": "https://www.ensembl.org/id/ENSGALT00010032059.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018849.1", "url": "https://www.ensembl.org/id/ENSGALP00010018849.1" } ] } }, { "isoform_ac": "A0A8V0YRR5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLS1/entry#A0A8V0YRR5-1", "sequence": { "sequence": "MDADFLNAFTQPAAVNQFLVENVITPGEKRKLIKPTSSNNPKLEQLKLLLIDWINTTLKEEHIVVKSLEEDLYDGLVLHHLLGSLKLDVDKIALTEKKQRQKLSVILEAVAKCLQLEESQLKWSVEAILAKDLLSTLHLLVAIAKHFQPSLAFPPNVHVETITIENTSKGLKTANGVEYITGSKENSEEQSTDDAFDELFSRAPERLDDVKKVFLQFVNQHVGKLGLNVKDMESQFADGVILLLLIGHLEGYFLNLRDFFLTPASTTEMLHNVNLALDLLTDGGLLNFSVNSEDIVKGDLKTTMRVLYCLYSKYKAKET", "length": 319, "header": "tr|A0A8V0YRR5-1|A0A8V0YRR5_CHICK Computationally mapped isoform of Gamma-parvin OS=Gallus gallus OX=9031 GN=PARVG PE=3 SV=1 CANONICAL=A0A8V0YLS1-1" }, "locus": { "chromosome": "1", "start_pos": 69279347, "end_pos": 69263965, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032078.1", "url": "https://www.ensembl.org/id/ENSGALT00010032078.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018868.1", "url": "https://www.ensembl.org/id/ENSGALP00010018868.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 36, "start_aa": "Thr", "end_pos": 36, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr36", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A9J7GV03-1", "protein_name": "Gamma-parvin", "gene_name": "Parvg", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MESEPLYNLLQLPKEVDQPTEEELPRGEKKKYLPPSSRKDPKFEELQKVLMEWINTTLLPEHIVVRSLEEDMFDGLILHHLFQKLAALKLEVEEISLTSASQRRKLGVILEAVNQSLQVEEQQAKWSVETIFNKDLLATLHLLVALAKHFQPELPLPDNVQVEVIHIESTKTGLKSDKLVEQLTEECSSHKDQPSQDTFDELFKLAPEKVHTVKEAIVSFVNQKVESLGLSVQSLDTQFADGVILLLLIGQLEGFFLHLKEFYLTPSSPTEMLHNVTLALELLKDEGLLNHPINPEDIVNKDAKSTLRILYSLFQKHALRTEGAGVPHGTPN", "length": 332 }, "evidence": [ { "id": "A0A8V0YLS1", "url": "https://omabrowser.org/oma/group/A0A8V0YLS1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0ABK0M1T9-1", "protein_name": "Gamma-parvin", "gene_name": "Parvg", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MESEFLYDLLQLPKEVAQPTEEELPRGGKKRYLSPNSKRNPKFEQLQKVLMEWINATLLPEHIVVRSLEEDMFDGLILHHLFQKLSSLKLEVEEISLTSASQRRKLGVILEAVNQSLQVEEQQAKWSVETIFNKDLLATLHLLVALAKRFQPDLPLPDNIQVEVIHIESTKMGLKSDKQVEQLTECNSHKDQPSQDAFDELFRLAPEKVHAVKEAIVSFVNQKLEGLGLSVQSLDTQFADGVILLLLIGQLEGFFLHLKEFYLTPSSPTEMLHNVTLALELLKDEGLCSYPINPEDIVNKDTKSTLRILYGLFQKHSLRAVGDRAHHGLLNFQLRDVCLCACSACDSQKRAPNPLEQDLQALVSCPTEMLRTELGSFRRTVSPFVCLFV", "length": 389 }, "evidence": [ { "id": "A0A8V0YLS1", "url": "https://omabrowser.org/oma/group/A0A8V0YLS1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9ERD8-1", "protein_name": "Gamma-parvin", "gene_name": "Parvg", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MELEFLYDLLQLPKEVAQPTEEELPRGGKKKYLSPNSKRNPKFEELQKVLMEWINTTLLPEHIVVRSLEEDMFDGLILHHLFQKLASLKLEVEEISLTSASQRHKLGVILEAVNQNLQVEEKQAKWSVETIFNKDLLATLHLLVALAKRFQPDLPLPDNVQVEVIHIESTKTGLKSDKQVEQLTECKSHKDQPLQDAFDELFKLAPEKVHAVQEAIVSFVNQKLERLGLSVQSLDTQFADGVILLLLIGQLEGFFLHLKEFYLTPSSPTEMLHNVTLALDLLKDEGLFSYPVNPEDIVNKDAKSTLRILYSLFQKHSLRAEGGGAHHATPN", "length": 331 }, "evidence": [ { "id": "A0A8V0YLS1", "url": "https://omabrowser.org/oma/group/A0A8V0YLS1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9HBI0-1", "protein_name": "Gamma-parvin", "gene_name": "PARVG", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEPEFLYDLLQLPKGVEPPAEEELSKGGKKKYLPPTSRKDPKFEELQKVLMEWINATLLPEHIVVRSLEEDMFDGLILHHLFQRLAALKLEAEDIALTATSQKHKLTVVLEAVNRSLQLEEWQAKWSVESIFNKDLLSTLHLLVALAKRFQPDLSLPTNVQVEVITIESTKSGLKSEKLVEQLTEYSTDKDEPPKDVFDELFKLAPEKVNAVKEAIVNFVNQKLDRLGLSVQNLDTQFADGVILLLLIGQLEGFFLHLKEFYLTPNSPAEMLHNVTLALELLKDEGLLSCPVSPEDIVNKDAKSTLRVLYGLFCKHTQKAHRDRTPHGAPN", "length": 331 }, "evidence": [ { "id": "A0A8V0YLS1", "url": "https://omabrowser.org/oma/group/A0A8V0YLS1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "actin binding", "id": "GO:0003779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003779", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLS1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLS1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLS1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLS1" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLS1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLS1" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLS1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLS1" } ], "pmid": "" }, { "name": "focal adhesion", "id": "GO:0005925", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005925", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLS1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLS1" } ], "pmid": "" }, { "name": "actin cytoskeleton", "id": "GO:0015629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015629", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLS1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLS1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "cell adhesion", "id": "GO:0007155", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007155", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLS1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLS1" } ], "pmid": "" }, { "name": "actin cytoskeleton organization", "id": "GO:0030036", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030036", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLS1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLS1" } ], "pmid": "" }, { "name": "substrate adhesion-dependent cell spreading", "id": "GO:0034446", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034446", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLS1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLS1" } ], "pmid": "" }, { "name": "establishment or maintenance of cell polarity regulating cell shape", "id": "GO:0071963", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071963", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLS1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLS1" } ], "pmid": "" }, { "name": "cell projection assembly", "id": "GO:0030031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030031", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLS1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLS1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 169, "end_pos": 171, "annotation": "n_glycosylation_sequon" }, { "start_pos": 290, "end_pos": 292, "annotation": "n_glycosylation_sequon" }, { "start_pos": 55, "end_pos": 57, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YLS1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLS1" }, { "id": "PS50021", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50021" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Calponin-homology (CH)", "eco_id": "ECO_0000259", "start_pos": 44, "end_pos": 151, "start_aa": "Glu", "end_aa": "Gln", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 36 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 169, "end_pos": 171 }, { "start_pos": 290, "end_pos": 292 }, { "start_pos": 55, "end_pos": 57 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YJ86-1", "uniprot_ac": "A0A8V0YJ86", "uniprot_id": "A0A8V0YJ86_CHICK", "mass": { "chemical_mass": 170538.0, "monoisotopic_mass": 170538.0 }, "refseq": {}, "gene_names": [ { "name": "CRACD", "type": "recommended", "evidence": [ { "id": "A0A8V0YJ86", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ86" } ] } ], "protein_names": [ { "name": "Capping protein inhibiting regulator of actin dynamics", "type": "synonym", "evidence": [ { "id": "A0A8V0YJ86", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ86/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJ86", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ86" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CRACD", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ86", "locus": { "chromosome": "4", "start_pos": 64326822, "end_pos": 64438181, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010015024", "url": "https://www.ensembl.org/id/ENSGALG00010015024" } ] } } ], "crossref": [ { "id": "422745", "url": "https://www.ncbi.nlm.nih.gov/gene/422745", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR028030", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028030", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052853", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052853", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ECKFAKD", "url": "https://omabrowser.org/oma/group/ECKFAKD/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YJ81", "url": "https://www.orthodb.org/?gene=A0A8V0YJ81", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YJ86", "url": "https://www.orthodb.org/?gene=A0A8V0YJ86", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YQN4", "url": "https://www.orthodb.org/?gene=A0A8V0YQN4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YQR7", "url": "https://www.orthodb.org/?gene=A0A8V0YQR7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YQS8", "url": "https://www.orthodb.org/?gene=A0A8V0YQS8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YSC5", "url": "https://www.orthodb.org/?gene=A0A8V0YSC5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YXF5", "url": "https://www.orthodb.org/?gene=A0A8V0YXF5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47574", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47574", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47574:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47574:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15262", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15262", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YJ81", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ81", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJ81-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ81-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJ86", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ86", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJ86-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ86-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQN4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQN4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQN4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQN4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQR7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQR7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQR7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQR7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQS8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQS8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQS8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQS8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YSC5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSC5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YSC5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSC5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YXF5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXF5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YXF5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXF5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MCHVTLVIIQHCLSVTFTPHKKKAGKFQPFKKLFGKRKKREPVSDCEEAKLKPSHSFGNVCNGTFSSDEEPNTGLRSSHYSMGSRAFSHDSIFIPDGRTESEQAIQAMSQENVLGKVKTLQQQLAKNIKFGQPPQMTISGRTMGEANASVEEDAFLGSLMEIDSQQDTVLSESGNKSADTPDLLRPMNLPGTGQMEEKVTPVKSSRPKRQFSCSGTIETINLDAVPQAVARLDNSAAKHKLSVKPKKQRMSRKHKRLTKGSQSLTITEFEPEDLETELFVDRYPGYNGHVTADKLIQNRDEPKQLQLAEEKRIEDHWGILEAEKIRQIVEMEEQRELEEQRCQELEEQMQKEQERRDSEKESSQYLLKGEISLKIEVQICQEEERRLLEAEKKQELENQTCQELEEQRQRELEEQQGPELEQQKSEEQDEQQRQELEEQKHQEWEKQEREKLEEQKHWVWDEQQRQELEEQKRQEHRQELQQHWEQEEQQRQELEEQKCQEQEQQRQKLEERKHWELEKQKRQELEEQKHQEWEEQKHKELEEQQRNELEEQERLELEELRQHETEKWCQEEEERNQLEEQKELVEQNKEEKQRQELEEEELPEAEIKLKQEKEVEGPSQQKKDEEEMQHLKEREKTEEDQPQQLPEKKQKQEEPRKHKLTKQMHLESTDIVQQDELKQQKEQEWNKLEEQKIDTEGQNLHRKQQEKSLEQQNDKNELWSGGADRNPANDKLQERPRPQKIKQPEKGNKTTEEILSQKLKREVDAQEQQRIGEELRWQEVDERQTASRPFTFQVSSGDKQIIFQKVNLSPVMPAKGAGLSSPSVKDSRMHASSKGSHTLPSSVCVPHTAILVTGAQLCGTAVNLNQIKDTACKSLLGLTEEKKNVDIPSPEKAQKKSPGPKPSSSKMKYTQEALDQATLAEWASIRSRILKNKENGKYNEKDRVNVCRHSDDWTPRGRGSPHGNLRKTLSANAKFSITPAWQKFSEASKTNSGTENISAAKGNEKVAVGRNIGLSTDANEDAVSTFKDNLSEMAKEKIETHSEITDNTEGCKFAKDLPSFLVPSFPRSPGKELPQPELPGALENQQSNSTKKPDKPAPNGEENVSPFGIKLRRTNYSLRFHYDQQVEQRKKKRYSAGDSFDGVPDPLLTTEGEKESAVFAPQESTSPGTGRANVHGSLKDSKDSSVIVLEISQPVGAPLPPPSQSALPPREKQACKSLFPQKPALAPKPASQTPPSSPLSKMNRSHLADTLGQRFVKAESDGGWRKDDRAVPPVALNESKNEEEEIREKKSFFPSLSIPWREKNDKKPEPLKKEKPVLQSRHSLDGSKLMEKVETSQPLWITLALQKQKGFREQQATREERRQAREAKQAEKLAKENAAVSNQSDNKSSSSSKTSALQKPTPQEGEKKIETAVSRLERREQLKKSNTLPTSVTVEISDSVPPPPLAKEVAKRFSTPDANPVSTEPAWLALAKRKAKAWSDCPQIIK", "length": 1486, "header": "tr|A0A8V0YJ86-1|A0A8V0YJ86_CHICK Isoform 1 of Capping protein inhibiting regulator of actin dynamics OS=Gallus gallus OX=9031 GN=CRACD PE=4 SV=1 CANONICAL=A0A8V0YJ86-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YJ81-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ86/entry#A0A8V0YJ81-1", "sequence": { "sequence": "MGSRAFSHDSIFIPDGRTESEQAIQAMSQENVLGKVKTLQSADTPDLLRPMNLPGTGQMEEKVTPVKSSRPKRQFSCSGTIETINLDAVPQAVARLDNSAAKHKLSVKPKKQRMSRKHKRLTKGSQSLTITEFEPEDLETELFVDRYPGYNGHVTADKLIQNRDEPKQLQLAEEKRIEDHWGILEAEKIRQIVEMEEQRELEEQRCQELEEQMQKEQERRDSEKESSQYLLKGEISLKIEVQICQEEERRLLEAEKKQELENQTCQELEEQRQRELEEQQGPELEQQKSEEQDEQQRQELEEQKHQEWEKQEREKLEEQKHWVWDEQQRQELEEQKRQEHRQELQQHWEQEEQQRQELEEQKCQEQEQQRQKLEERKHWELEKQKRQELEEQKHQEWEEQKHKELEEQQRNELEEQERLELEELRQHETEKWCQEEEERNQLEEQKELVEQNKEEKQRQELEEEELPEAEIKLKQEKEVEGPSQQKKDEEEMQHLKEREKTEEDQPQQLPEKKQKQEEPRKHKLTKQMHLESTDIVQQDELKQQKEQEWNKLEEQKIDTEGQNLHRKQQEKSLEQQNDKNELWSGGADRNPANDKLQERPRPQKIKQPEKGNKTTEEILSQKLKREVDAQEQQRIGEELRWQEVDERQTASRPFTFQVSSGDKQIIFQKVNLSPVMPAKGAGLSSPSVKDSRMHASSKGSHTLPSSVCVPHTAILVTGAQLCGTAVNLNQIKDTACKSLLGLTEEKKNVDIPSPEKAQKKSPGPKPSSSKMKYTQEALDQATLAEWASIRSRILKNKENGKYNEKDRVNVCRHSDDWTPRGRGSPHGNLRKTLSANAKFSITPAWQKFSEASKTNSGTENISAAKGNEKVAVGRNIGLSTDANEDAVSTFKDNLSEMAKEKIETHSEITDNTEGCKFAKDLPSFLVPSFPRSPGKELPQPELPGALENQQSNSTKKPDKPAPNGEENVSPFGIKLRRTNYSLRFHYDQQVEQRKKKRYSAGDSFDGVPDPLLTTEGEKESAVFAPQESTSPGTGRANVHGSLKDSKDSSVIVLEISQPVGAPLPPPSQSALPPREKQACKSLFPQKPALAPKPASQTPPSSPLSKMNRSHLADTLGQRFVKAESDGGWRKDDRAVPPVALNESKNEEEEIREKKSFFPSLSIPWREKNDKKPEPLKKEKPVLQSRHSLDGSKLMEKVETSQPLWITLALQKQKGFREQQATREERRQAREAKQAEKLAKENAAVSNQSDNKSSSSSKTSALQKPTPQEGEKKIETAVSRLERREQLKKSNTLPTSVTVEISDSVPPPPLAKEVAKRFSTPDANPVSTEPAWLALAKRKAKAWSDCPQIIK", "length": 1350, "header": "tr|A0A8V0YJ81-1|A0A8V0YJ86_CHICK Computationally mapped isoform of Capping protein inhibiting regulator of actin dynamics OS=Gallus gallus OX=9031 GN=CRACD PE=4 SV=1 CANONICAL=A0A8V0YJ86-1" }, "locus": { "chromosome": "4", "start_pos": 64350863, "end_pos": 64329871, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010036122.1", "url": "https://www.ensembl.org/id/ENSGALT00010036122.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020981.1", "url": "https://www.ensembl.org/id/ENSGALP00010020981.1" } ] } }, { "isoform_ac": "A0A8V0YJ86-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ86/entry#A0A8V0YJ86-1", "sequence": { "sequence": "MCHVTLVIIQHCLSVTFTPHKKKAGKFQPFKKLFGKRKKREPVSDCEEAKLKPSHSFGNVCNGTFSSDEEPNTGLRSSHYSMGSRAFSHDSIFIPDGRTESEQAIQAMSQENVLGKVKTLQQQLAKNIKFGQPPQMTISGRTMGEANASVEEDAFLGSLMEIDSQQDTVLSESGNKSADTPDLLRPMNLPGTGQMEEKVTPVKSSRPKRQFSCSGTIETINLDAVPQAVARLDNSAAKHKLSVKPKKQRMSRKHKRLTKGSQSLTITEFEPEDLETELFVDRYPGYNGHVTADKLIQNRDEPKQLQLAEEKRIEDHWGILEAEKIRQIVEMEEQRELEEQRCQELEEQMQKEQERRDSEKESSQYLLKGEISLKIEVQICQEEERRLLEAEKKQELENQTCQELEEQRQRELEEQQGPELEQQKSEEQDEQQRQELEEQKHQEWEKQEREKLEEQKHWVWDEQQRQELEEQKRQEHRQELQQHWEQEEQQRQELEEQKCQEQEQQRQKLEERKHWELEKQKRQELEEQKHQEWEEQKHKELEEQQRNELEEQERLELEELRQHETEKWCQEEEERNQLEEQKELVEQNKEEKQRQELEEEELPEAEIKLKQEKEVEGPSQQKKDEEEMQHLKEREKTEEDQPQQLPEKKQKQEEPRKHKLTKQMHLESTDIVQQDELKQQKEQEWNKLEEQKIDTEGQNLHRKQQEKSLEQQNDKNELWSGGADRNPANDKLQERPRPQKIKQPEKGNKTTEEILSQKLKREVDAQEQQRIGEELRWQEVDERQTASRPFTFQVSSGDKQIIFQKVNLSPVMPAKGAGLSSPSVKDSRMHASSKGSHTLPSSVCVPHTAILVTGAQLCGTAVNLNQIKDTACKSLLGLTEEKKNVDIPSPEKAQKKSPGPKPSSSKMKYTQEALDQATLAEWASIRSRILKNKENGKYNEKDRVNVCRHSDDWTPRGRGSPHGNLRKTLSANAKFSITPAWQKFSEASKTNSGTENISAAKGNEKVAVGRNIGLSTDANEDAVSTFKDNLSEMAKEKIETHSEITDNTEGCKFAKDLPSFLVPSFPRSPGKELPQPELPGALENQQSNSTKKPDKPAPNGEENVSPFGIKLRRTNYSLRFHYDQQVEQRKKKRYSAGDSFDGVPDPLLTTEGEKESAVFAPQESTSPGTGRANVHGSLKDSKDSSVIVLEISQPVGAPLPPPSQSALPPREKQACKSLFPQKPALAPKPASQTPPSSPLSKMNRSHLADTLGQRFVKAESDGGWRKDDRAVPPVALNESKNEEEEIREKKSFFPSLSIPWREKNDKKPEPLKKEKPVLQSRHSLDGSKLMEKVETSQPLWITLALQKQKGFREQQATREERRQAREAKQAEKLAKENAAVSNQSDNKSSSSSKTSALQKPTPQEGEKKIETAVSRLERREQLKKSNTLPTSVTVEISDSVPPPPLAKEVAKRFSTPDANPVSTEPAWLALAKRKAKAWSDCPQIIK", "length": 1486, "header": "tr|A0A8V0YJ86-1|A0A8V0YJ86_CHICK Isoform 1 of Capping protein inhibiting regulator of actin dynamics OS=Gallus gallus OX=9031 GN=CRACD PE=4 SV=1 CANONICAL=A0A8V0YJ86-1" }, "locus": { "chromosome": "4", "start_pos": 64367230, "end_pos": 64329871, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010036127.1", "url": "https://www.ensembl.org/id/ENSGALT00010036127.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020986.1", "url": "https://www.ensembl.org/id/ENSGALP00010020986.1" } ] } }, { "isoform_ac": "A0A8V0YQN4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ86/entry#A0A8V0YQN4-1", "sequence": { "sequence": "MGSRAFSHDSIFIPDGRTESEQAIQAMSQENVLGKVKTLQQQLAKNIKFGQPPQMTISGRTMGEANASVEEDAFLGSLMEIDSQQDTVLSESGNKSADTPDLLRPMNLPGTGQMEEKVTPVKSSRPKRQFSCSGTIETINLDAVPQAVARLDNSAAKHKLSVKPKKQRMSRKHKRLTKGSQSLTITEFEPEDLETELFVDRYPGYNGHVTADKLIQNRDEPKQLQLAEEKRIEDHWGILEAEKIRQIVEMEEQRELEEQRCQELEEQMQKEQERRDSEKESSQYLLKGEISLKIEVQICQEEERRLLEAEKKQELENQTCQELEEQRQRELEEQQGPELEQQKSEEQDEQQRQELEEQKHQEWEKQEREKLEEQKHWVWDEQQRQELEEQKRQEHRQELQQHWEQEEQQRQELEEQKCQEQEQQRQKLEERKHWELEKQKRQELEEQKHQEWEEQKHKELEEQQRNELEEQERLELEELRQHETEKWCQEEEERNQLEEQKELVEQNKEEKQRQELEEEELPEAEIKLKQEKEVEGPSQQKKDEEEMQHLKEREKTEEDQPQQLPEKKQKQEEPRKHKLTKQMHLESTDIVQQDELKQQKEQEWNKLEEQKIDTEGQNLHRKQQEKSLEQQNDKNELWSGGADRNPANDKLQERPRPQKIKQPEKGNKTTEEILSQKLKREVDAQEQQRIGEELRWQEVDERQTASRPFTFQVSSGDKQIIFQKVNLSPVMPAKGAGLSSPSVKDSRMHASSKGSHTLPSSVCVPHTAILVTGAQLCGTAVNLNQIKDTACKSLLGLTEEKKNVDIPSPEKAQKKSPGPKPSSSKMKYTQEALDQATLAEWASIRSRILKNKENGKYNEKDRVNVCRHSDDWTPRGRGSPHGNLRKTLSANAKFSITPAWQKFSEASKTNSGTENISAAKGNEKVAVGRNIGLSTDANEDAVSTFKDNLSEMAKEKIETHSEITDNTEGCKFAKDLPSFLVPSFPRSPGKELPQPELPGALENQQSNSTKKPDKPAPNGEENVSPFGIKLRRTNYSLRFHYDQQVEQRKKKRYSAGDSFDGVPDPLLTTEGEKESAVFAPQESTSPGTGRANVHGSLKDSKDSSVIVLEISQPVGAPLPPPSQSALPPREKQACKSLFPQKPALAPKPASQTPPSSPLSKMNRSHLADTLGQRFVKAESDGGWRKDDRAVPPVALNESKNEEEEIREKKSFFPSLSIPWREKNDKKPEPLKKEKPVLQSRHSLDGSKLMEKVETSQPLWITLALQKQKGFREQQATREERRQAREAKQAEKLAKENAAVSNQSDNKSSSSSKTSALQKPTPQEGEKKIETAVSRLERREQLKKSNTLPTSVTVEISDSVPPPPLAKEVAKRFSTPDANPVSTEPAWLALAKRKAKAWSDCPQIINIIVLIFP", "length": 1412, "header": "tr|A0A8V0YQN4-1|A0A8V0YQN4_CHICK Computationally mapped isoform of Capping protein inhibiting regulator of actin dynamics OS=Gallus gallus OX=9031 GN=CRACD PE=4 SV=1 CANONICAL=A0A8V0YJ86-1" }, "locus": { "chromosome": "4", "start_pos": 64350863, "end_pos": 64329260, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010036134.1", "url": "https://www.ensembl.org/id/ENSGALT00010036134.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020993.1", "url": "https://www.ensembl.org/id/ENSGALP00010020993.1" } ] } }, { "isoform_ac": "A0A8V0YQR7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ86/entry#A0A8V0YQR7-1", "sequence": { "sequence": "MGKAVTLVAGSLSVAEIMLTLQSSHYSMGSRAFSHDSIFIPDGRTESEQAIQAMSQENVLGKVKTLQQQLAKNIKFGQPPQMTISGRTMGEANASVEEDAFLGSLMEIDSQQDTVLSESGNKSADTPDLLRPMNLPGTGQMEEKVTPVKSSRPKRQFSCSGTIETINLDAVPQAVARLDNSAAKHKLSVKPKKQRMSRKHKRLTKGSQSLTITEFEPEDLETELFVDRYPGYNGHVTADKLIQNRDEPKQLQLAEEKRIEDHWGILEAEKIRQIVEMEEQRELEEQRCQELEEQMQKEQERRDSEKESSQYLLKGEISLKIEVQICQEEERRLLEAEKKQELENQTCQELEEQRQRELEEQQGPELEQQKSEEQDEQQRQELEEQKHQEWEKQEREKLEEQKHWVWDEQQRQELEEQKRQEHRQELQQHWEQEEQQRQELEEQKCQEQEQQRQKLEERKHWELEKQKRQELEEQKHQEWEEQKHKELEEQQRNELEEQERLELEELRQHETEKWCQEEEERNQLEEQKELVEQNKEEKQRQELEEEELPEAEIKLKQEKEVEGPSQQKKDEEEMQHLKEREKTEEDQPQQLPEKKQKQEEPRKHKLTKQMHLESTDIVQQDELKQQKEQEWNKLEEQKIDTEGQNLHRKQQEKSLEQQNDKNELWSGGADRNPANDKLQERPRPQKIKQPEKGNKTTEEILSQKLKREVDAQEQQRIGEELRWQEVDERQTASRPFTFQVSSGDKQIIFQKVNLSPVMPAKGAGLSSPSVKDSRMHASSKGSHTLPSSVCVPHTAILVTGAQLCGTAVNLNQIKDTACKSLLGLTEEKKNVDIPSPEKAQKKSPGPKPSSSKMKYTQEALDQATLAEWASIRSRILKNKENGKYNEKDRVNVCRHSDDWTPRGRGSPHGNLRKTLSANAKFSITPAWQKFSEASKTNSGTENISAAKGNEKVAVGRNIGLSTDANEDAVSTFKDNLSEMAKEKIETHSEITDNTEGCKFAKDLPSFLVPSFPRSPGKELPQPELPGALENQQSNSTKKPDKPAPNGEENVSPFGIKLRRTNYSLRFHYDQQVEQRKKKRYSAGDSFDGVPDPLLTTEGEKESAVFAPQESTSPGTGRANVHGSLKDSKDSSVIVLEISQPVGAPLPPPSQSALPPREKQACKSLFPQKPALAPKPASQTPPSSPLSKMNRSHLADTLGQRFVKAESDGGWRKDDRAVPPVALNESKNEEEEIREKKSFFPSLSIPWREKNDKKPEPLKKEKPVLQSRHSLDGSKLMEKVETSQPLWITLALQKQKGFREQQATREERRQAREAKQAEKLAKENAAVSNQSDNKSSSSSKTSALQKPTPQEGEKKIETAVSRLERREQLKKSNTLPTSVTVEISDSVPPPPLAKEVAKRFSTPDANPVSTEPAWLALAKRKAKAWSDCPQIIK", "length": 1432, "header": "tr|A0A8V0YQR7-1|A0A8V0YQR7_CHICK Computationally mapped isoform of Capping protein inhibiting regulator of actin dynamics OS=Gallus gallus OX=9031 GN=CRACD PE=4 SV=1 CANONICAL=A0A8V0YJ86-1" }, "locus": { "chromosome": "4", "start_pos": 64377030, "end_pos": 64329871, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010036131.1", "url": "https://www.ensembl.org/id/ENSGALT00010036131.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020990.1", "url": "https://www.ensembl.org/id/ENSGALP00010020990.1" } ] } }, { "isoform_ac": "A0A8V0YQS8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ86/entry#A0A8V0YQS8-1", "sequence": { "sequence": "MGSRAFSHDSIFIPDGRTESEQAIQAMSQENVLGKVKTLQQQLAKNIKFGQPPQMTISGRTMGEANASVEEDAFLGSLMEIDSQQDTVLSESGNKSADTPDLLRPMNLPGTGQMEEKVTPVKSSRPKRQFSCSGTIETINLDAVPQAVARLDNSAAKHKLSVKPKKQRMSRKHKRLTKGSQSLTITEFEPEDLETELFVDRYPGYNGHVTADKLIQNRDEPKQLQLAEEKRIEDHWGILEAEKIRQIVEMEEQRELEEQRCQELEEQMQKEQERRDSEKESSQYLLKGEISLKIEVQICQEEERRLLEAEKKQELENQTCQELEEQRQRELEEQQGPELEQQKSEEQDEQQRQELEEQKHQEWEKQEREKLEEQKHWVWDEQQRQELEEQKRQEHRQELQQHWEQEEQQRQELEEQKCQEQEQQRQKLEERKHWELEKQKRQELEEQKHQEWEEQKHKELEEQQRNELEEQERLELEELRQHETEKWCQEEEERNQLEEQKELVEQNKEEKQRQELEEEELPEAEIKLKQEKEVEGPSQQKKDEEEMQHLKEREKTEEDQPQQLPEKKQKQEEPRKHKLTKQMHLESTDIVQQDELKQQKEQEWNKLEEQKIDTEGQNLHRKQQEKSLEQQNDKNELWSGGADRNPANDKLQERPRPQKIKQPEKGNKTTEEILSQKLKREVDAQEQQRIGEELRWQEVDERQTASRPFTFQVSSGDKQIIFQKVNLSPVMPAKGAGLSSPSVKDSRMHASSKGSHTLPSSVCVPHTAILVTGAQLCGTAVNLNQIKDTACKSLLGLTEEKKNVDIPSPEKAQKKSPGPKPSSSKMKYTQEALDQATLAEWASIRSRILKNKENGKYNEKDRVNVCRHSDDWTPRGRGSPHGNLRKTLSANAKFSITPAWQKFSEASKTNSGTENISAAKGNEKVAVGRNIGLSTDANEDAVSTFKDNLSEMAKEKIETHSEITDNTEGCKFAKDLPSFLVPSFPRSPGKELPQPELPGALENQQSNSTKKPDKPAPNGEENVSPFGIKLRRTNYSLRFHYDQQVEQRKKKRYSAGDSFDGVPDPLLTTEGEKESAVFAPQESTSPGTGRANVHGSLKDSKDSSVIVLEISQPVGAPLPPPSQSALPPREKQACKSLFPQKPALAPKPASQTPPSSPLSKMNRSHLADTLGQRFVKAESDGGWRKDDRAVPPVALNESKNEEEEIREKKSFFPSLSIPWREKNDKKPEPLKKEKPVLQSRHSLDGSKLMEKVETSQPLWITLALQKQKGFREQQATREERRQAREAKQAEKLAKENAAVSNQSDNKSSSSSKTSALQKPTPQEGEKKIETAVSRLERREQLKKSNTLPTSVTVEISDSVPPPPLAKEVAKRFSTPDANPVSTEPAWLALAKRKAKAWSDCPQIIK", "length": 1405, "header": "tr|A0A8V0YQS8-1|A0A8V0YQS8_CHICK Computationally mapped isoform of Capping protein inhibiting regulator of actin dynamics OS=Gallus gallus OX=9031 GN=CRACD PE=4 SV=1 CANONICAL=A0A8V0YJ86-1" }, "locus": { "chromosome": "4", "start_pos": 64350863, "end_pos": 64329871, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010036143.1", "url": "https://www.ensembl.org/id/ENSGALT00010036143.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021000.1", "url": "https://www.ensembl.org/id/ENSGALP00010021000.1" } ] } }, { "isoform_ac": "A0A8V0YSC5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ86/entry#A0A8V0YSC5-1", "sequence": { "sequence": "MSADTPDLLRPMNLPGTGQMEEKVTPVKSSRPKRQFSCSGTIETINLDAVPQAVARLDNSAAKHKLSVKPKKQRMSRKHKRLTKGSQSLTITEFEPEDLETELFVDRYPGYNGHVTADKLIQNRDEPKQLQLAEEKRIEDHWGILEAEKIRQIVEMEEQRELEEQRCQELEEQMQKEQERRDSEKESSQYLLKGEISLKIEVQICQEEERRLLEAEKKQELENQTCQELEEQRQRELEEQQGPELEQQKSEEQDEQQRQELEEQKHQEWEKQEREKLEEQKHWVWDEQQRQELEEQKRQEHRQELQQHWEQEEQQRQELEEQKCQEQEQQRQKLEERKHWELEKQKRQELEEQKHQEWEEQKHKELEEQQRNELEEQERLELEELRQHETEKWCQEEEERNQLEEQKELVEQNKEEKQRQELEEEELPEAEIKLKQEKEVEGPSQQKKDEEEMQHLKEREKTEEDQPQQLPEKKQKQEEPRKHKLTKQMHLESTDIVQQDELKQQKEQEWNKLEEQKIDTEGQNLHRKQQEKSLEQQNDKNELWSGGADRNPANDKLQERPRPQKIKQPEKGNKTTEEILSQKLKREVDAQEQQRIGEELRWQEVDERQTASRPFTFQVSSGDKQIIFQKVNLSPVMPAKGAGLSSPSVKDSRMHASSKGSHTLPSSVCVPHTAILVTGAQLCGTAVNLNQIKDTACKSLLGLTEEKKNVDIPSPEKAQKKSPGPKPSSSKMKYTQEALDQATLAEWASIRSRILKNKENGKYNEKDRVNVCRHSDDWTPRGRGSPHGNLRKTLSANAKFSITPAWQKFSEASKTNSGTENISAAKGNEKVAVGRNIGLSTDANEDAVSTFKDNLSEMAKEKIETHSEITDNTEGCKFAKDLPSFLVPSFPRSPGKELPQPELPGALENQQSNSTKKPDKPAPNGEENVSPFGIKLRRTNYSLRFHYDQQVEQRKKKRYSAGDSFDGVPDPLLTTEGEKESAVFAPQESTSPGTGRANVHGSLKDSKDSSVIVLEISQPVGAPLPPPSQSALPPREKQACKSLFPQKPALAPKPASQTPPSSPLSKMNRSHLADTLGQRFVKAESDGGWRKDDRAVPPVALNESKNEEEEIREKKSFFPSLSIPWREKNDKKPEPLKKEKPVLQSRHSLDGSKLMEKVETSQPLWITLALQKQKGFREQQATREERRQAREAKQAEKLAKENAAVSNQSDNKSSSSSKTSALQKPTPQEGEKKIETAVSRLERREQLKKSNTLPTSVTVEISDSVPPPPLAKEVAKRFSTPDANPVSTEPAWLALAKRKAKAWSDCPQIIK", "length": 1311, "header": "tr|A0A8V0YSC5-1|A0A8V0YSC5_CHICK Computationally mapped isoform of Capping protein inhibiting regulator of actin dynamics OS=Gallus gallus OX=9031 GN=CRACD PE=4 SV=1 CANONICAL=A0A8V0YJ86-1" }, "locus": { "chromosome": "4", "start_pos": 64340865, "end_pos": 64329871, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010036120.1", "url": "https://www.ensembl.org/id/ENSGALT00010036120.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020979.1", "url": "https://www.ensembl.org/id/ENSGALP00010020979.1" } ] } }, { "isoform_ac": "A0A8V0YXF5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ86/entry#A0A8V0YXF5-1", "sequence": { "sequence": "MINLFKKPYKKKAGKFQPFKKLFGKRKKREPVSDCEEAKLKPSHSFGNVCNGTFSSDEEPNTGLRSSHYSMGSRAFSHDSIFIPDGRTESEQAIQAMSQENVLGKVKTLQQQLAKNIKFGQPPQMTISGRTMGEANASVEEDAFLGSLMEIDSQQDTVLSESGNKSADTPDLLRPMNLPGTGQMEEKVTPVKSSRPKRQFSCSGTIETINLDAVPQAVARLDNSAAKHKLSVKPKKQRMSRKHKRLTKGSQSLTITEFEPEDLETELFVDRYPGYNGHVTADKLIQNRDEPKQLQLAEEKRIEDHWGILEAEKIRQIVEMEEQRELEEQRCQELEEQMQKEQERRDSEKESSQYLLKGEISLKIEVQICQEEERRLLEAEKKQELENQTCQELEEQRQRELEEQQGPELEQQKSEEQDEQQRQELEEQKHQEWEKQEREKLEEQKHWVWDEQQRQELEEQKRQEHRQELQQHWEQEEQQRQELEEQKCQEQEQQRQKLEERKHWELEKQKRQELEEQKHQEWEEQKHKELEEQQRNELEEQERLELEELRQHETEKWCQEEEERNQLEEQKELVEQNKEEKQRQELEEEELPEAEIKLKQEKEVEGPSQQKKDEEEMQHLKEREKTEEDQPQQLPEKKQKQEEPRKHKLTKQMHLESTDIVQQDELKQQKEQEWNKLEEQKIDTEGQNLHRKQQEKSLEQQNDKNELWSGGADRNPANDKLQERPRPQKIKQPEKGNKTTEEILSQKLKREVDAQEQQRIGEELRWQEVDERQTASRPFTFQVSSGDKQIIFQKVNLSPVMPAKGAGLSSPSVKDSRMHASSKGSHTLPSSVCVPHTAILVTGAQLCGTAVNLNQIKDTACKSLLGLTEEKKNVDIPSPEKAQKKSPGPKPSSSKMKYTQEALDQATLAEWASIRSRILKNKENGKYNEKDRVNVCRHSDDWTPRGRGSPHGNLRKTLSANAKFSITPAWQKFSEASKTNSGTENISAAKGNEKVAVGRNIGLSTDANEDAVSTFKDNLSEMAKEKIETHSEITDNTEGCKFAKDLPSFLVPSFPRSPGKELPQPELPGALENQQSNSTKKPDKPAPNGEENVSPFGIKLRRTNYSLRFHYDQQVEQRKKKRYSAGDSFDGVPDPLLTTEGEKESAVFAPQESTSPGTGRANVHGSLKDSKDSSVIVLEISQPVGAPLPPPSQSALPPREKQACKSLFPQKPALAPKPASQTPPSSPLSKMNRSHLADTLGQRFVKAESDGGWRKDDRAVPPVALNESKNEEEEIREKKSFFPSLSIPWREKNDKKPEPLKKEKPVLQSRHSLDGSKLMEKVETSQPLWITLALQKQKGFREQQATREERRQAREAKQAEKLAKENAAVSNQSDNKSSSSSKTSALQKPTPQEGEKKIETAVSRLERREQLKKSNTLPTSVTVEISDSVPPPPLAKEVAKRFSTPDANPVSTEPAWLALAKRKAKAWSDCPQIIK", "length": 1475, "header": "tr|A0A8V0YXF5-1|A0A8V0YXF5_CHICK Computationally mapped isoform of Capping protein inhibiting regulator of actin dynamics OS=Gallus gallus OX=9031 GN=CRACD PE=4 SV=1 CANONICAL=A0A8V0YJ86-1" }, "locus": { "chromosome": "4", "start_pos": 64374630, "end_pos": 64329871, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010036138.1", "url": "https://www.ensembl.org/id/ENSGALT00010036138.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020997.1", "url": "https://www.ensembl.org/id/ENSGALP00010020997.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0ABK0LCY4-1", "protein_name": "Capping protein inhibiting regulator of actin dynamics", "gene_name": "Cracd", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTVFLSLMGEQKVSRQFKQCHRTASWAKSKLFRCVLFFSRLSSMFLRQLGKNIKFGQRPSNVIPMKKAGSADASSEEDFVLTSPMEIVTQQDIVLSDTENKSSDTPSSSSPLNLPEAGSDMEEKVAPVKPSRPKRHISSAGTIESVNLDAIPLAIARLDNSAAKHKLSVKPKNQRVSRKHRWLAQDRQNAPGSFESQSSLDQNGQLGEDKHIGQGEEPEPLESHEEKRLQEDYWRELEAKCKKQKAEAAEKRRLEEQRRQALERRLWEESLRQELLEEEEEEAEEVGLLLQAGKAPPEEGPQSGLEEQRGSEQELGEADDPTRLEAEERRREQEKAERQAEKLRQREEAERQEEELRQREEAERQAEELRQREEAERQEEELRQREAENQEEKLRQREAEKQEEEVRQREVEGQEEELKQREAKRQEEELRQLEEAERQEKLRQREAQKQEEEELRQREAERHEKLRQHEAERQEEELRQRERQRAQEEEAKRMLQEEEEAKHIEELKGREKEAPEPLVEEGSQGPEGESQPWLTDDADQQSPLQRDLEKPGEREDLVSAGQRDIPEDQRGEVEMAIEPVEQSGDWGAHFGGVDGVDVEGKEASQIDNPQPQERQKEGTPAREEKEATAADIDRKVEELRWQEVDERPRPYTFQVSSGSRQILFPKVNLSPVTPAKDASLAPAAQEPPAPRGAASHALPSALSIPHTAILVTGAQLCGPAVNLSQIKDSACKSLLGLSEEKRPADVPTVEPRAGGGKSKPAPESPSNAVALAEWASIRSRILKNSEGDQRGDREPARVGDEPAPRARCDSRGNVRKTPPVNAKFSIMPAWQKFSDSGAETFKQSTDGESVRKKPGPAPSEETTPTPQPLPAGAPELQKNLEKQEVSQEPPDTTDGCKFAKDLPSFLVPSLPSPQKAASRTESTTSLDSETTSDVGSPDPAMPGGEEKASPFGIKLRRTNYSLRFHCDQQAEQKKKKRHSSTGDSVDGDAPPGERNPEATFLKHGPSLPQERRPALAPRRDSAESHPSGHCVAAAVHPGLPPASGQTPAPEQDKVASKTPLSMQKPALAPKPASQTPPSSPLSKLSRPHIVELLTRRAGKLDSEPSEPAKENQESRDSQPPSPSLLEEPKGQKRDEKDVLEKKPASPPLPSSQQERPSLTPETGRKEKPMLQSRHSLDGSKLTEKAETAQPLWITLALQKQKGFREQQATREERKQAREAKQAEKLSKETASVSQQPGSSRVSKAGSVHKPAAPSEEKKPETAVSKLQRREQLKKSNTLPTSVTVEISDSAPSAPLVKEVTKRFSTPDAAPVSTEPAWLALAKRKAKAWSDCPQIIK", "length": 1336 }, "evidence": [ { "id": "A0A8V0YJ86", "url": "https://omabrowser.org/oma/group/A0A8V0YJ86/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5PR69-3", "protein_name": "Capping protein-inhibiting regulator of actin dynamics", "gene_name": "Cracd", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": 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"https://www.ebi.ac.uk/interpro/entry/pfam/PF02060", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YJ84", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ84", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJ84-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ84-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAFSNHTNGSSIMPKLFHMYVEQKKTLRFNNHSNPALEMQEEIMASFYILIIVGFFGFLLFVMMLSNIVSSKPENYIDYLYSGKLNPQRSRVELSGKETALFPHTEPLP", "length": 109, "header": "tr|A0A8V0YJ84-1|A0A8V0YJ84_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=3 SV=1 CANONICAL=A0A8V0YJ84-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YJ84-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ84/entry#A0A8V0YJ84-1", "sequence": { "sequence": "MAFSNHTNGSSIMPKLFHMYVEQKKTLRFNNHSNPALEMQEEIMASFYILIIVGFFGFLLFVMMLSNIVSSKPENYIDYLYSGKLNPQRSRVELSGKETALFPHTEPLP", "length": 109, "header": "tr|A0A8V0YJ84-1|A0A8V0YJ84_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=3 SV=1 CANONICAL=A0A8V0YJ84-1" }, "locus": { "chromosome": "1", "start_pos": 105959727, "end_pos": 105958669, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030828.1", "url": "https://www.ensembl.org/id/ENSGALT00010030828.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017887.1", "url": "https://www.ensembl.org/id/ENSGALP00010017887.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJ84", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ84" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, 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"sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YM16-1", "uniprot_ac": "A0A8V0YM16", "uniprot_id": "A0A8V0YM16_CHICK", "mass": { "chemical_mass": 25825.0, "monoisotopic_mass": 25825.0 }, "refseq": {}, "gene_names": [ { "name": "NDFIP1", "type": "recommended", "evidence": [ { "id": "A0A8V0YM16", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM16" } ] } ], "protein_names": [ { "name": "Nedd4 family interacting protein 1", "type": "synonym", "evidence": [ { "id": "A0A8V0YM16", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM16/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YM16", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM16" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "NDFIP1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM16", "locus": { "chromosome": "13", "start_pos": 16802417, "end_pos": 16783742, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013353", "url": "https://www.ensembl.org/id/ENSGALG00010013353" } ] } } ], "crossref": [ { "id": "A0A8V0YM16", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YM16", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd22305", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22305", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR019325", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019325", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YJD5", "url": "https://www.orthodb.org/?gene=A0A8V0YJD5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YJE1", "url": "https://www.orthodb.org/?gene=A0A8V0YJE1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YJH5", "url": "https://www.orthodb.org/?gene=A0A8V0YJH5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YM06", "url": "https://www.orthodb.org/?gene=A0A8V0YM06", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YM16", "url": "https://www.orthodb.org/?gene=A0A8V0YM16", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YRW6", "url": "https://www.orthodb.org/?gene=A0A8V0YRW6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YRX5", "url": "https://www.orthodb.org/?gene=A0A8V0YRX5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YRZ7", "url": "https://www.orthodb.org/?gene=A0A8V0YRZ7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13396", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13396", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13396:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13396:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10176", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10176", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YJD5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJD5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJD5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJD5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJE1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJE1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJE1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJE1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJH5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJH5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJH5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJH5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YM06", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM06", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YM06-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM06-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YM16", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM16", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YM16-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM16-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YRW6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRW6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YRW6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRW6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YRX5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRX5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YRX5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRX5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YRZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRZ7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YRZ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRZ7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "RRHPSPAWGALNFRIASDRNLPSTALALQNEEEPGEAAPVVSDAPPPYSSISAENTAYFDYKDESGFPKPPSYNVATTLPSYDEAERTKAEATIPLVPGREEDFVTRDDFDDSDQLRIGNDGIFMLTFFMAFLFNWIGFFLSFCLTTSAAGRYGAISGFGLSLIKWILIVRFSTYFPGYFDGQYWLWWVFLVLGFLLFLRGFINYAKVRKMPDTFSTLPRTRVLFIY", "length": 227, "header": "tr|A0A8V0YM16-1|A0A8V0YM16_CHICK Isoform 1 of Nedd4 family interacting protein 1 OS=Gallus gallus OX=9031 GN=NDFIP1 PE=4 SV=1 CANONICAL=A0A8V0YM16-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YJD5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM16/entry#A0A8V0YJD5-1", "sequence": { "sequence": "MLISCRVIYTKLWEAWCTKHTVFSEVLRCEELQNEEEPGEAAPVVSDAPPPYSSISAENTAYFDYKDESGFPKPPSYNVATTLPSYDEAERTKAEATIPLVPGREEDFVTRDDFDDSDQLRIGNDGIFMLTFFMAFLFNWIGFFLSFCLTTSAAGRYGAISGFGLSLIKWILIVRFSTYFPGYFDGQYWLWWVFLVLGFLLFLRGFINYAKVRKMPDTFSTLPRTRVLFIY", "length": 231, "header": "tr|A0A8V0YJD5-1|A0A8V0YM16_CHICK Computationally mapped isoform of Nedd4 family interacting protein 1 OS=Gallus gallus OX=9031 GN=NDFIP1 PE=4 SV=2 CANONICAL=A0A8V0YM16-1" }, "locus": { "chromosome": "13", "start_pos": 16799640, "end_pos": 16794970, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032139.1", "url": "https://www.ensembl.org/id/ENSGALT00010032139.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018929.1", "url": "https://www.ensembl.org/id/ENSGALP00010018929.1" } ] } }, { "isoform_ac": "A0A8V0YJE1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM16/entry#A0A8V0YJE1-1", "sequence": { "sequence": "GLELNAVSLQNEEEPGEAAPVVSDAPPPYSSISAENTAYFDYKDESGFPKPPSYNVATTLPSYDEAERTKAEATIPLVPGREEDFVTRDDFDDSDQLRIGNDGIFMLTFFMAFLFNWIGFFLSFCLTTSAAGRYGAISGFGLSLIKWILIVRFSTYFPGYFDGQYWLWWVFLVLGFLLFLRGFINYAKVRKMPDTFSTLPRTRVLFIY", "length": 208, "header": "tr|A0A8V0YJE1-1|A0A8V0YJE1_CHICK Computationally mapped isoform of Nedd4 family interacting protein 1 OS=Gallus gallus OX=9031 GN=NDFIP1 PE=4 SV=1 CANONICAL=A0A8V0YM16-1" }, "locus": { "chromosome": "13", "start_pos": 16799640, "end_pos": 16789930, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032144.1", "url": "https://www.ensembl.org/id/ENSGALT00010032144.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018934.1", "url": "https://www.ensembl.org/id/ENSGALP00010018934.1" } ] } }, { "isoform_ac": "A0A8V0YJH5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM16/entry#A0A8V0YJH5-1", "sequence": { "sequence": "MRLQNEEEPGEAAPVVSDAPPPYSSISAENTAYFDYKDESGFPKPPSYNVATTLPSYDEAERTKAEATIPLVPGREEDFVTRDDFDDSDQLRIGNDGIFMLTFFMAFLFNWIGFFLSFCLTTSAAGRYGAISGFGLSLIKWILIVRFSTYFPGYFDGQYWLWWVFLVLGFLLFLRGFINYAKVRKMPDTFSTLPRTRVLFIY", "length": 202, "header": "tr|A0A8V0YJH5-1|A0A8V0YJH5_CHICK Computationally mapped isoform of Nedd4 family interacting protein 1 OS=Gallus gallus OX=9031 GN=NDFIP1 PE=4 SV=1 CANONICAL=A0A8V0YM16-1" }, "locus": { "chromosome": "13", "start_pos": 16799640, "end_pos": 16787750, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032175.1", "url": "https://www.ensembl.org/id/ENSGALT00010032175.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018965.1", "url": "https://www.ensembl.org/id/ENSGALP00010018965.1" } ] } }, { "isoform_ac": "A0A8V0YM06-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM16/entry#A0A8V0YM06-1", "sequence": { "sequence": "DGNHLLVYRAIKHPDTRTAPAELQNEEEPGEAAPVVSDAPPPYSSISAENTAYFDYKDESGFPKPPSYNVATTLPSYDEAERTKAEATIPLVPGREEDFVTRDDFDDSDQLRIGNDGIFMLTFFMAFLFNWIGFFLSFCLTTSAAGRYGAISGFGLSLIKWILIVRFSTYFPGYFDGQYWLWWVFLVLGFLLFLRGFINYAKVRKMPDTFSTLPRTRVLFIY", "length": 222, "header": "tr|A0A8V0YM06-1|A0A8V0YM06_CHICK Computationally mapped isoform of Nedd4 family interacting protein 1 OS=Gallus gallus OX=9031 GN=NDFIP1 PE=4 SV=1 CANONICAL=A0A8V0YM16-1" }, "locus": { "chromosome": "13", "start_pos": 16799640, "end_pos": 16792109, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032159.1", "url": "https://www.ensembl.org/id/ENSGALT00010032159.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018949.1", "url": "https://www.ensembl.org/id/ENSGALP00010018949.1" } ] } }, { "isoform_ac": "A0A8V0YM16-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM16/entry#A0A8V0YM16-1", "sequence": { "sequence": "RRHPSPAWGALNFRIASDRNLPSTALALQNEEEPGEAAPVVSDAPPPYSSISAENTAYFDYKDESGFPKPPSYNVATTLPSYDEAERTKAEATIPLVPGREEDFVTRDDFDDSDQLRIGNDGIFMLTFFMAFLFNWIGFFLSFCLTTSAAGRYGAISGFGLSLIKWILIVRFSTYFPGYFDGQYWLWWVFLVLGFLLFLRGFINYAKVRKMPDTFSTLPRTRVLFIY", "length": 227, "header": "tr|A0A8V0YM16-1|A0A8V0YM16_CHICK Isoform 1 of Nedd4 family interacting protein 1 OS=Gallus gallus OX=9031 GN=NDFIP1 PE=4 SV=1 CANONICAL=A0A8V0YM16-1" }, "locus": { "chromosome": "13", "start_pos": 16799640, "end_pos": 16788002, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032169.1", "url": "https://www.ensembl.org/id/ENSGALT00010032169.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018959.1", "url": "https://www.ensembl.org/id/ENSGALP00010018959.1" } ] } }, { "isoform_ac": "A0A8V0YRW6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM16/entry#A0A8V0YRW6-1", "sequence": { "sequence": "MIRMLQNEEEPGEAAPVVSDAPPPYSSISAENTAYFDYKDESGFPKPPSYNVATTLPSYDEAERTKAEATIPLVPGREEDFVTRDDFDDSDQLRIGNDGIFMLTFFMAFLFNWIGFFLSFCLTTSAAGRYGAISGFGLSLIKWILIVRFSTYFPGYFDGQYWLWWVFLVLGFLLFLRGFINYAKVRKMPDTFSTLPRTRVLFIY", "length": 204, "header": "tr|A0A8V0YRW6-1|A0A8V0YRW6_CHICK Computationally mapped isoform of Nedd4 family interacting protein 1 OS=Gallus gallus OX=9031 GN=NDFIP1 PE=4 SV=1 CANONICAL=A0A8V0YM16-1" }, "locus": { "chromosome": "13", "start_pos": 16799640, "end_pos": 16791487, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032141.1", "url": "https://www.ensembl.org/id/ENSGALT00010032141.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018931.1", "url": "https://www.ensembl.org/id/ENSGALP00010018931.1" } ] } }, { "isoform_ac": "A0A8V0YRX5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM16/entry#A0A8V0YRX5-1", "sequence": { "sequence": "FCLVCSARRSPSRVEIPLGRAVCLRSSQLQNEEEPGEAAPVVSDAPPPYSSISAENTAYFDYKDESGFPKPPSYNVATTLPSYDEAERTKAEATIPLVPGREEDFVTRDDFDDSDQLRIGNDGIFMLTFFMAFLFNWIGFFLSFCLTTSAAGRYGAISGFGLSLIKWILIVRFSTYFPGYFDGQYWLWWVFLVLGFLLFLRGFINYAKVRKMPDTFSTLPRTRVLFIY", "length": 228, "header": "tr|A0A8V0YRX5-1|A0A8V0YRX5_CHICK Computationally mapped isoform of Nedd4 family interacting protein 1 OS=Gallus gallus OX=9031 GN=NDFIP1 PE=4 SV=1 CANONICAL=A0A8V0YM16-1" }, "locus": { "chromosome": "13", "start_pos": 16799640, "end_pos": 16788698, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032151.1", "url": "https://www.ensembl.org/id/ENSGALT00010032151.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018941.1", "url": "https://www.ensembl.org/id/ENSGALP00010018941.1" } ] } }, { "isoform_ac": "A0A8V0YRZ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM16/entry#A0A8V0YRZ7-1", "sequence": { "sequence": "MDNTLPPFFLSLPVAACLQMIKLLQWRVSELQNEEEPGEAAPVVSDAPPPYSSISAENTAYFDYKDESGFPKPPSYNVATTLPSYDEAERTKAEATIPLVPGREEDFVTRDDFDDSDQLRIGNDGIFMLTFFMAFLFNWIGFFLSFCLTTSAAGRYGAISGFGLSLIKWILIVRFSTYFPGYFDGQYWLWWVFLVLGFLLFLRGFINYAKVRKMPDTFSTLPRTRVLFIY", "length": 230, "header": "tr|A0A8V0YRZ7-1|A0A8V0YRZ7_CHICK Computationally mapped isoform of Nedd4 family interacting protein 1 OS=Gallus gallus OX=9031 GN=NDFIP1 PE=4 SV=1 CANONICAL=A0A8V0YM16-1" }, "locus": { "chromosome": "13", "start_pos": 16799640, "end_pos": 16786041, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032177.1", "url": "https://www.ensembl.org/id/ENSGALT00010032177.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018967.1", "url": "https://www.ensembl.org/id/ENSGALP00010018967.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "vacuolar transport", "id": "GO:0007034", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007034", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YM16", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM16" } ], "pmid": "" }, { "name": "intracellular iron ion homeostasis", "id": "GO:0006879", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006879", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YM16", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM16" } ], "pmid": "" }, { "name": "proteasome-mediated ubiquitin-dependent protein catabolic process", "id": "GO:0043161", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043161", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YM16", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM16" } ], "pmid": "" }, { "name": "positive regulation of protein ubiquitination", "id": "GO:0031398", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031398", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YM16", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM16" } ], "pmid": "" }, { "name": "ubiquitin-dependent protein catabolic process", "id": "GO:0006511", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006511", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YM16", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM16" } ], "pmid": "" }, { "name": "metal ion transport", "id": "GO:0030001", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030001", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YM16", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM16" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YM16", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM16" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": 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binding", "id": "GO:0050699", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050699", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YM16", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM16" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": 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"o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YJD8-1", "uniprot_ac": "A0A8V0YJD8", "uniprot_id": "A0A8V0YJD8_CHICK", "mass": { "chemical_mass": 26772.0, "monoisotopic_mass": 26772.0 }, "refseq": {}, "gene_names": [ { "name": "GRPEL2", "type": "recommended", "evidence": [ { "id": "A0A8V0YJD8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJD8" } ] } ], "protein_names": [ { "name": "GrpE protein homolog 2, mitochondrial", "type": "recommended", "evidence": [ { "id": "A0A8V0YJD8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJD8/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. Seems to control the nucleotide-dependent binding of mitochondrial HSP70 to substrate proteins. Stimulates ATPase activity of mt-HSP70. May also serve to modulate the interconversion of oligomeric (inactive) and monomeric (active) forms of mt-HSP70.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCG1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCG1#function" }, { "database": "UniProtKB", "id": "ARBA00055238", "url": "https://www.uniprot.org/uniprotkb/ARBA00055238#function" }, { "database": "UniProtKB", "id": "A0A8V0YJD8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJD8#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJD8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJD8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "GRPEL2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJD8", "locus": { "chromosome": "13", "start_pos": 8133156, "end_pos": 8143138, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010011784", "url": "https://www.ensembl.org/id/ENSGALG00010011784" } ] } } ], "crossref": [ { "id": "A0A8V0YJD8", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YJD8", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00446", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00446", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000740", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000740", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009012", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009012", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013805", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013805", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YCG1", "url": "https://www.orthodb.org/?gene=A0A8V0YCG1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YJD8", "url": "https://www.orthodb.org/?gene=A0A8V0YJD8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21237", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21237", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21237:SF10", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21237:SF10", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01025", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01025", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YCG1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCG1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YCG1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCG1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJD8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJD8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJD8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJD8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "KELKSCLESCVPAFSNDAKLKLFHLTVLEVNFPFLVTSLYFRESLCVFSTAAQQRSTGDECGPEDPRDEPKHPLSDCALEHKAIKLEEQVRDLTERYRKALADSENVRRRTQKFVEDAKLFGIQSFCRDLVEVADILEKTAESAAEEAEPTNPNPTLQKIYEGLSLIEAKLQSVFAKHGLQKMSPVGDKYDPYDHEIVCHVPAEGMQPGTIALVTQDGYKLHGRTIRHALVGVAVESQE", "length": 239, "header": "tr|A0A8V0YJD8-1|A0A8V0YJD8_CHICK Isoform 1 of GrpE protein homolog 2, mitochondrial OS=Gallus gallus OX=9031 GN=GRPEL2 PE=3 SV=1 CANONICAL=A0A8V0YJD8-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YCG1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJD8/entry#A0A8V0YCG1-1", "sequence": { "sequence": "GQQAARGAWPSARCGPGLGCPSARRGRAGATAAQQRSTGDECGPEDPRDEPKHPLSDCALEHKAIKLEEQVRDLTERYRKALADSENVRRRTQKFVEDAKLFGIQSFCRDLVEVADILEKTAESAAEEAEPTNPNPTLQKIYEGLSLIEAKLQSVFAKHGLQKMSPVGDKYDPYDHEIVCHVPAEGMQPGTIALVTQDGYKLHGRTIRHALVGVAVESQE", "length": 220, "header": "tr|A0A8V0YCG1-1|A0A8V0YCG1_CHICK Computationally mapped isoform of GrpE protein homolog 2, mitochondrial OS=Gallus gallus OX=9031 GN=GRPEL2 PE=3 SV=1 CANONICAL=A0A8V0YJD8-1" }, "locus": { "chromosome": "13", "start_pos": 8143138, "end_pos": 8136923, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028180.1", "url": "https://www.ensembl.org/id/ENSGALT00010028180.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016155.1", "url": "https://www.ensembl.org/id/ENSGALP00010016155.1" } ] } }, { "isoform_ac": "A0A8V0YJD8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJD8/entry#A0A8V0YJD8-1", "sequence": { "sequence": "KELKSCLESCVPAFSNDAKLKLFHLTVLEVNFPFLVTSLYFRESLCVFSTAAQQRSTGDECGPEDPRDEPKHPLSDCALEHKAIKLEEQVRDLTERYRKALADSENVRRRTQKFVEDAKLFGIQSFCRDLVEVADILEKTAESAAEEAEPTNPNPTLQKIYEGLSLIEAKLQSVFAKHGLQKMSPVGDKYDPYDHEIVCHVPAEGMQPGTIALVTQDGYKLHGRTIRHALVGVAVESQE", "length": 239, "header": "tr|A0A8V0YJD8-1|A0A8V0YJD8_CHICK Isoform 1 of GrpE protein homolog 2, mitochondrial OS=Gallus gallus OX=9031 GN=GRPEL2 PE=3 SV=1 CANONICAL=A0A8V0YJD8-1" }, "locus": { "chromosome": "13", "start_pos": 8139451, "end_pos": 8136923, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028176.1", "url": "https://www.ensembl.org/id/ENSGALT00010028176.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016154.1", "url": "https://www.ensembl.org/id/ENSGALP00010016154.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "protein homodimerization activity", "id": "GO:0042803", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042803", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJD8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJD8" } ], "pmid": "" }, { "name": "unfolded protein binding", "id": "GO:0051082", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051082", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJD8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJD8" } ], "pmid": "" }, { "name": "protein-folding chaperone binding", "id": "GO:0051087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051087", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJD8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJD8" } ], "pmid": "" }, { "name": "adenyl-nucleotide exchange factor activity", "id": "GO:0000774", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000774", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJD8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJD8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "protein folding", "id": "GO:0006457", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006457", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJD8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJD8" } ], "pmid": "" }, { "name": "protein import into mitochondrial matrix", "id": "GO:0030150", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030150", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJD8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJD8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "PAM complex, Tim23 associated import motor", "id": "GO:0001405", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001405", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJD8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJD8" } ], "pmid": "" }, { "name": "mitochondrial matrix", "id": "GO:0005759", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005759", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJD8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJD8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", 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"refseq": { "ac": "XP_015147043", "name": "PHD finger protein 13 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015147043" }, "gene_names": [ { "name": "LOC101747338", "type": "recommended", "evidence": [ { "id": "A0A8V0YJF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJF0" } ] }, { "name": "LOC101747338", "type": "synonym", "evidence": [ { "id": "XP_015147043", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015147043" } ] } ], "protein_names": [ { "name": "PHD finger protein 13", "type": "recommended", "evidence": [ { "id": "A0A8V0YJF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJF0/entry#names_and_taxonomy" } ] }, { "name": "PHD finger protein 13 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_015147043", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015147043" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052540.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015147043.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015147043", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015147043" } ] }, { "annotation": "Modulates chromatin structure and DNA damage response by regulating key determinants of chromatin compaction and DNA damage response. Binds H3K4me3-containing chromatin and promotes DNA condensation by recruiting corepressors such as TRIM28 and H3K9 methyltransferase SETDB1. Required for normal chromosome condensation during the early stages of mitosis. Required for normal chromosome separation during mitosis. Increases both chromatin-associated levels and activity of H3K9 methyltransferases, such as SETDB1, thus enhancing H3K9 trimethylation. 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{ "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YJG7-1", "uniprot_ac": "A0A8V0YJG7", "uniprot_id": "A0A8V0YJG7_CHICK", "mass": { "chemical_mass": 28277.0, "monoisotopic_mass": 28277.0 }, "refseq": { "ac": "XP_040561634", "name": "EEF1A lysine methyltransferase 4", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040561634" }, "gene_names": [ { "name": "LOC431092", "type": "recommended", "evidence": [ { "id": "A0A8V0YJG7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJG7" } ] }, { "name": "LOC431092", "type": "synonym", "evidence": [ { "id": "XP_040561634", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040561634" } ] } ], "protein_names": [ { "name": "EEF1A lysine methyltransferase 4", "type": "recommended", "evidence": [ { "id": "A0A8V0YJG7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJG7/entry#names_and_taxonomy" } ] }, { "name": "EEF1A lysine methyltransferase 4", "type": "synonym", "evidence": [ { "id": "XP_040561634", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040561634" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052540.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040561634", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040561634" } ] }, { "annotation": "Protein-lysine methyltransferase that efficiently catalyzes three successive methylations on 'Lys-36' in eukaryotic translation elongation factor 1 alpha (EEF1A1 or EEF1A2).", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJG7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJG7#function" }, { "database": "UniProtKB", "id": "ARBA00059299", "url": "https://www.uniprot.org/uniprotkb/ARBA00059299#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJG7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJG7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LOC431092", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJG7", "locus": {} } ], "crossref": [ { "id": "A0A8V0YJG7", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YJG7", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd02440", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02440", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "431092", "url": "https://www.ncbi.nlm.nih.gov/gene/431092", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013216", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013216", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029063", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029063", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051419", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051419", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "HWAVMDA", "url": "https://omabrowser.org/oma/group/HWAVMDA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YJG7", "url": "https://www.orthodb.org/?gene=A0A8V0YJG7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12176", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12176", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12176:SF80", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12176:SF80", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF08241", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08241", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_040561634", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040561634", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "51736", "url": "https://www.rhea-db.org/rhea/51736", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "54196", "url": "https://www.rhea-db.org/rhea/54196", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "54200", "url": "https://www.rhea-db.org/rhea/54200", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YJG7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJG7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJG7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJG7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MERRPPPAAANRCYAQRRFWEERYRRAGAEPREWLGDFERFRALLEPELRPDDRILVLGCGTSALSYELHELGYPDVTSIDFSPACVEAMRSRYAHCPQLRWAVMDMRSLTFPDASFDVVLEKGTLDVLLVEEADPWHVSPRGAAAMRRVLAEVSRVLRPGGRFLSITFAQPHFRAPHYAQEAFGWLLRHAACGDAFHYFVYIMCKGQPLAPRDLALGRQLGRPPPAPPPPVTMAEDEDEDFLRAIEL", "length": 248, "header": "tr|A0A8V0YJG7-1|A0A8V0YJG7_CHICK Isoform 1 of EEF1A lysine methyltransferase 4 OS=Gallus gallus OX=9031 GN=LOC431092 PE=3 SV=1 CANONICAL=A0A8V0YJG7-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YJG7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJG7/entry#A0A8V0YJG7-1", "sequence": { "sequence": "MERRPPPAAANRCYAQRRFWEERYRRAGAEPREWLGDFERFRALLEPELRPDDRILVLGCGTSALSYELHELGYPDVTSIDFSPACVEAMRSRYAHCPQLRWAVMDMRSLTFPDASFDVVLEKGTLDVLLVEEADPWHVSPRGAAAMRRVLAEVSRVLRPGGRFLSITFAQPHFRAPHYAQEAFGWLLRHAACGDAFHYFVYIMCKGQPLAPRDLALGRQLGRPPPAPPPPVTMAEDEDEDFLRAIEL", "length": 248, "header": "tr|A0A8V0YJG7-1|A0A8V0YJG7_CHICK Isoform 1 of EEF1A lysine methyltransferase 4 OS=Gallus gallus OX=9031 GN=LOC431092 PE=3 SV=1 CANONICAL=A0A8V0YJG7-1" }, "locus": { "chromosome": "9", "start_pos": 15570531, "end_pos": 15567147, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010036244.1", "url": "https://www.ensembl.org/id/ENSGALT00010036244.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021071.1", "url": "https://www.ensembl.org/id/ENSGALP00010021071.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "D4ADU7-1", "protein_name": "EEF1A lysine methyltransferase 4", "gene_name": "Eef1akmt4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASPRTPVSPPELPERNLQYRQVQYWDQRYKDAADSGPYEWFGDFASFRALLEPELCPEDRILVLGCGNSALSYELFLGGFPNVTSVDYSPVVVAAMQVRYAHVPSLRWETMDIRALDFPSGSFDVVLEKGTLDALLAGEPDPWNVSSEGVHTVDQVLSEVSRVLVPGGRFISMTPAGPHFRIRHYAQPCYDWSLRHTTYSSGFHFHFYVMHKGRELTVSQLALGAQILSPPSPPAPPCFLQDSDNEDFLSAIQL", "length": 255 }, "evidence": [ { "id": "A0A8V0YJG7", "url": "https://omabrowser.org/oma/group/A0A8V0YJG7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P0DPD7-4", "protein_name": "EEF1A lysine methyltransferase 4", "gene_name": "EEF1AKMT4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MASPGAGRAPPELPERNCGYREVEYWDQRYQGAADSAPYDWFGDFSSFRALLEPELRPEDRILVLGCGNSALSYELFLGGFPNVTSVDYSSVVVAAMQARHAHVPQLRWETMDVRKLDFPSASFDVVLEKGTLDALLAGERDPWTVSSEGVHTVDQVLSEVSRVLVPGGRFISMTSAAPHFRTRHYAQAYYGWSLRHATYGSGFHFHLYLMHKGGKLSVAQLALGAQILSPPRPPTSPCFLQDSDHEDFLSAIQL", "length": 255 }, "evidence": [ { "id": "A0A8V0YJG7", "url": "https://omabrowser.org/oma/group/A0A8V0YJG7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0DPE0-1", "protein_name": "EEF1A lysine methyltransferase 4", "gene_name": "Eef1akmt4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASPRTPVSPPELPEKNFQYRQVQYWDQRYKDAADSGPYEWFGDFASFRALLEPELCPEDRILVLGCGNSALSYELFLGGFPNVTSVDYSPVVVAAMQVRYAHVPSLRWETMDVRALDFPSGSFDVVLEKGTLDAMLAGEPDPWNVSSEGVHTVDQVLSEVSRLLVPGGRFISMTSAGPHFRIRHYAQSRYDWSLRHTTYSSGFHFHFYIMHKGRALSVSQLALGAQILSSPSPPASPCFLQDSDNEDFLSAIQL", "length": 255 }, "evidence": [ { "id": "A0A8V0YJG7", "url": "https://omabrowser.org/oma/group/A0A8V0YJG7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P0DPE2-1", "protein_name": "EEF1AKMT4-ECE2 readthrough transcript protein", "gene_name": "EEF1AKMT4-ECE2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MACLGPSAQVPELPEKNCGYREVQYWDQRYQGAADSAPYEWFGDFSCFRDLLEPELRPLDRILVLGCGNSALSYEIFLGGFPDVTSVDYSSVVVAAMRARYAHVPTLRWETMDVRALGFPSGSFDVVLEKGTLDALLTGEQDPWTVSSEGVHTVDQVLNEAGFRKRTSRLLGLHTQLELVLAGVSLLLAALLLGCLVALGVQYHRDPSHSTCLTEACIRVAGKILESLDRGVSPCEDFYQFSCGGWIRRNPLPDGRSRWNTFNSLWDQNQAILKHLLENTTFNSSSEAERKTQRFYLSCLQVERIEELGAQPLRDLIDKIGGWNVTGPWDQDNFMEVLKAVAGTYRATPFFTVYVSADSKSSNSNIIQVDQSGLFLPSRDYYLNRTANEKVLTAYLDYMEELGMLLGGQPTSTREQMRQVLELEIQLANITVPQDQRRDEEKIYHKMSIAELQALAPSMDWLEFLSFLLSPLELGDSEPVVVYGTDYLQQVSELINRTEPSVLNNYLIWNLVQKTTSSLDHRFESAQEKLLETLYGTKKSCTPRWQTCISNTDDALGFALGSLFVKATFDRQSKEIAEGMISEIRAAFEEALGHLVWMDEKTRQAAKEKADAIYDMIGFPDFILEPKELDDVYDGYEVSEDSFFQNMLNLYNFSAKVMADQLRKPPSRDQWSMTPQTVNAYYLPTKNEIVFPAGILQAPFYTCNHPKALNFGGIGVVMGHELTHAFDDQGREYDKEGNLRPWWQNESLAAFRNHTACIEEQYSQYQVNGEKLNGRQTLGENIADNGGLKAAYNAYKAWLRKHGEEQQLPAVGLTNHQLFFVGFAQVWCSVRTPESSHEGLVTDPHSPARFRVLGTLSNSRDFLRHFGCPVGSPMNSGQLCEVW", "length": 883 }, "evidence": [ { "id": "A0A8V0YJG7", "url": "https://omabrowser.org/oma/group/A0A8V0YJG7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "methylation", "id": "GO:0032259", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032259", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJG7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJG7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "protein-lysine N-methyltransferase activity", "id": "GO:0016279", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016279", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJG7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJG7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "51736", "name": "", "equation": "L-lysyl-[protein] + S-adenosyl-L-methionine = N(6)-methyl-L-lysyl-[protein] + S-adenosyl-L-homocysteine + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A0A0MQ47-1", "A0A8V0Y4K0-1", "E1C5V0-1", "A0A8V0ZUS5-1", "Q5F3V0-1" ], "evidence": [ { "id": "51736", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/51736" } ] }, { "id": "54196", "name": "", "equation": "N(6)-methyl-L-lysyl-[protein] + S-adenosyl-L-methionine = N(6),N(6)-dimethyl-L-lysyl-[protein] + S-adenosyl-L-homocysteine + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "54196", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/54196" } ] }, { "id": "54200", "name": "", "equation": "N(6),N(6)-dimethyl-L-lysyl-[protein] + S-adenosyl-L-methionine = N(6),N(6),N(6)-trimethyl-L-lysyl-[protein] + S-adenosyl-L-homocysteine + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "54200", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/54200" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A0A0MQ47", "gene_name": "SMYD2", "activity": [ { "ec_number": "2.1.1.354", "activity": "L-lysyl(4)-[histone H3] + 3 S-adenosyl-L-methionine = N(6),N(6),N(6)-trimethyl-L-lysyl(4)-[histone H3] + 3 S-adenosyl-L-homocysteine + 3 H(+).", "evidence": [ { "id": "A0A0A0MQ47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A0A0MQ47" } ] }, { "ec_number": "2.1.1.354", "activity": "", "evidence": [ { "id": "A0A0A0MQ47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A0A0MQ47" } ] } ] }, { "uniprot_ac": "A0A8V0Y4K0", "gene_name": "SETD7", "activity": [ { "ec_number": "2.1.1.364", "activity": "L-lysyl(4)-[histone H3] + S-adenosyl-L-methionine = N(6)-methyl-L-lysyl(4)-[histone H3] + S-adenosyl-L-homocysteine + H(+).", "evidence": [ { "id": "A0A8V0Y4K0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y4K0" } ] }, { "ec_number": "2.1.1.364", "activity": "", "evidence": [ { "id": "A0A8V0Y4K0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y4K0" } ] } ] }, { "uniprot_ac": "A0A8V0ZUS5", "gene_name": "KMT5A", "activity": [ { "ec_number": "2.1.1.361", "activity": "L-lysyl(20)-[histone H4] + S-adenosyl-L-methionine = N(6)-methyl-L-lysyl(20)-[histone H4] + S-adenosyl-L-homocysteine + H(+).", "evidence": [ { "id": "A0A8V0ZUS5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUS5" } ] }, { "ec_number": "2.1.1.361", "activity": "", "evidence": [ { "id": "A0A8V0ZUS5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUS5" } ] } ] }, { "uniprot_ac": "E1C5V0", "gene_name": "SMYD2", "activity": [ { "ec_number": "2.1.1.-", "activity": "", "evidence": [ { "id": "E1C5V0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C5V0" } ] }, { "ec_number": "2.1.1.354", "activity": "L-lysyl(4)-[histone H3] + 3 S-adenosyl-L-methionine = N(6),N(6),N(6)-trimethyl-L-lysyl(4)-[histone H3] + 3 S-adenosyl-L-homocysteine + 3 H(+).", "evidence": [ { "id": "E1C5V0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C5V0" } ] } ] }, { "uniprot_ac": "Q5F3V0", "gene_name": "SMYD4", "activity": [ { "ec_number": "2.1.1.-", "activity": "", "evidence": [ { "id": "Q5F3V0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F3V0" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YJG7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJG7" }, { "id": "PF08241", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08241" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Methyltransferase type 11", "eco_id": "ECO_0000259", "start_pos": 57, "end_pos": 165, "start_aa": "Val", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YJH4-1", "uniprot_ac": "A0A8V0YJH4", "uniprot_id": "A0A8V0YJH4_CHICK", "mass": { "chemical_mass": 49685.0, "monoisotopic_mass": 49685.0 }, "refseq": { "ac": "XP_015134050", "name": "Krueppel-like factor 5 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015134050" }, "gene_names": [ { "name": "LOC430697", "type": "recommended", "evidence": [ { "id": "A0A8V0YJH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJH4" } ] }, { "name": "LOC430697", "type": "synonym", "evidence": [ { "id": "XP_015134050", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015134050" } ] } ], "protein_names": [ { "name": "C2H2-type domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A8V0YJH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJH4/entry#names_and_taxonomy" } ] }, { "name": "Krueppel-like factor 5 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015134050", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015134050" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052535.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015134050.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015134050", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015134050" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJH4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJH4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LOC430697", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJH4", "locus": {} } ], "crossref": [ { "id": "A0A8V0YJH4", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YJH4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000007570", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000007570", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd21579", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd21579", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "430697", "url": "https://www.ncbi.nlm.nih.gov/gene/430697", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:430697", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:430697", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YSVNINL", "url": "https://omabrowser.org/oma/group/YSVNINL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YJH4", "url": "https://www.orthodb.org/?gene=A0A8V0YJH4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1BZV5", "url": "https://www.orthodb.org/?gene=E1BZV5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23235", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23235", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23235:SF77", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23235:SF77", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015134050", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015134050", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Y6B8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y6B8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y6B8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y6B8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YB51", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB51", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YB51-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB51-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YB56", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB56", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YB56-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB56-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YCJ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCJ0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YCJ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCJ0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJH4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJH4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJH4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJH4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BZV5", "url": "https://www.uniprot.org/uniprotkb/E1BZV5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BZV5-1", "url": "https://www.uniprot.org/uniprotkb/E1BZV5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSSGLVLCAPLPDDSSAFTPLKPVTMSGEPGEDTSVFEDIKPPARAPDNPPDLAQLHPMRMEQRMPLTLEGRSEMDKYLSSQLPPIPMIPDKKYRRESASVVDEFFSTEKPNSTPYSVNINVILPDTTHLRTGLYRSPKPMTPFTQIKTEPGTSFSQPCSSTSGSTQTLPDFTSVFSMPQSVAVNNIFIKQEMPSDIPLSSSSQQAQFYQMPLGNGNADLTNLTPSSNSTTAINSLSGVTMSTGNAMSSVLHRHVQAGGPVKQYPHISQGQENFNISGQFYAVPGVNLPPSPPNSQPGSPENQPELINTISPPPSYEATFGLKLVQSSQVPPVPNSLGTLCQGPTVMQTLKYNRRNNPELEKRRIHHCDYPGCTKVYTKSSHLKAHQRTHTGEKPYKCTWDGCDWRFARSDELTRHYRKHTGAKPFKCLACGRCFSRSDHLALHMKRHQN", "length": 450, "header": "tr|A0A8V0YJH4-1|A0A8V0YJH4_CHICK Isoform 1 of C2H2-type domain-containing protein OS=Gallus gallus OX=9031 GN=LOC430697 PE=4 SV=1 CANONICAL=A0A8V0YJH4-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Y6B8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJH4/entry#A0A8V0Y6B8-1", "sequence": { "sequence": "MSSGLVLCAPLPDDSSAFTPLKPVTMSGEPGEDTSVFEDIKPPARAPDNPPDLAQLHPMRMEQRMPLTLEGRSEMDKYLSSQLPPIPMIPDKKYRRESASVVDEFFSTEKPNSTPYSVNINVILPDTTHLRTGLYRSPKPMTPFTQIKTEPGTSFSQPCSSTSGSTQTLPDFTSVFSMPQSVAVNNIFIKQEMPSDIPLSSSSQQAQFYQMPLGNGNADLTNLTPSSNSTTAINSLSGVTMSTGNAMSSVLHRHVQAGGPVKQYPHISQGQENFNISGQFYAVPGVNLPPSPPNSQPGSPENQPELINTISPPPSYEATFGLKLVQSSQVPPVPNSLGTLCQGPTVMQTLKYNRRNNPELEKRRIHHCDYPGEKPYKCTWDGCDWRFARSDELTRHYRKHTGAKPFKCLACGRCFSRSDHLALHMKRHQN", "length": 430, "header": "tr|A0A8V0Y6B8-1|A0A8V0Y6B8_CHICK Computationally mapped isoform of C2H2-type domain-containing protein OS=Gallus gallus OX=9031 GN=LOC430697 PE=4 SV=1 CANONICAL=A0A8V0YJH4-1" }, "locus": { "chromosome": "4", "start_pos": 11417681, "end_pos": 11398829, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028257.1", "url": "https://www.ensembl.org/id/ENSGALT00010028257.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016188.1", "url": "https://www.ensembl.org/id/ENSGALP00010016188.1" } ] } }, { "isoform_ac": "A0A8V0YB51-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJH4/entry#A0A8V0YB51-1", "sequence": { "sequence": "MSSGLVLCAPLPDDSSAFTPLKPVTMSGEPGEDTSVFEDIKPPARAPDNPPDLAQGRSEMDKYLSSQLPPIPMIPDKKYRRESASVVDEFFSTEKPNSTPYSVNINVILPDTTHLRTGLYRSPKPMTPFTQIKTEPGTSFSQPCSSTSGSTQTLPDFTSVFSMPQSVAVNNIFIKQEMPSDIPLSSSSQQAQFYQMPLGNGNADLTNLTPSSNSTTAINSLSGVTMSTGNAMSSVLHRHVQAGGPVKQYPHISQGQENFNISGQFYAVPGVNLPPSPPNSQPGSPENQPELINTISPPPSYEATFGLKLVQSSQVPPVPNSLGTLCQGPTVMQTLKYNRRNNPELEKRRIHHCDYPGCTKVYTKSSHLKAHQRTHTGEKPYKCTWDGCDWRFARSDELTRHYRKHTGAKPFKCLACGRCFSRSDHLALHMKRHQN", "length": 435, "header": "tr|A0A8V0YB51-1|A0A8V0YB51_CHICK Computationally mapped isoform of C2H2-type domain-containing protein OS=Gallus gallus OX=9031 GN=LOC430697 PE=4 SV=1 CANONICAL=A0A8V0YJH4-1" }, "locus": { "chromosome": "4", "start_pos": 11417681, "end_pos": 11398829, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028263.1", "url": "https://www.ensembl.org/id/ENSGALT00010028263.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016192.1", "url": "https://www.ensembl.org/id/ENSGALP00010016192.1" } ] } }, { "isoform_ac": "A0A8V0YB56-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJH4/entry#A0A8V0YB56-1", "sequence": { "sequence": "MRMEQRMPLTLEGRSEMDKYLSSQLPPIPMIPDKKYRRESASVVDEFFSTEKPNSTPYSVNINVILPDTTHLRTGLYRSPKPMTPFTQIKTEPGTSFSQPCSSTSGSTQTLPDFTSVFSMPQSVAVNNIFIKQEMPSDIPLSSSSQQAQFYQMPLGNGNADLTNLTPSSNSTTAINSLSGVTMSTGNAMSSVLHRHVQAGGPVKQYPHISQGQENFNISGQFYAVPGVNLPPSPPNSQPGSPENQPELINTISPPPSYEATFGLKLVQSSQVPPVPNSLGTLCQGPTVMQTLKYNRRNNPELEKRRIHHCDYPGCTKVYTKSSHLKAHQRTHTGEKPYKCTWDGCDWRFARSDELTRHYRKHTGAKPFKCLACGRCFSRSDHLALHMKRHQN", "length": 392, "header": "tr|A0A8V0YB56-1|A0A8V0YB56_CHICK Computationally mapped isoform of C2H2-type domain-containing protein OS=Gallus gallus OX=9031 GN=LOC430697 PE=4 SV=1 CANONICAL=A0A8V0YJH4-1" }, "locus": { "chromosome": "4", "start_pos": 11408119, "end_pos": 11398829, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028272.1", "url": "https://www.ensembl.org/id/ENSGALT00010028272.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016197.1", "url": "https://www.ensembl.org/id/ENSGALP00010016197.1" } ] } }, { "isoform_ac": "A0A8V0YCJ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJH4/entry#A0A8V0YCJ0-1", "sequence": { "sequence": "MGDVRISTKGRICKYADVFNDLAPCSISSASRRMARDRSHWSQLHPMRMEQRMPLTLEGRSEMDKYLSSQLPPIPMIPDKKYRRESASVVDEFFSTEKPNSTPYSVNINVILPDTTHLRTGLYRSPKPMTPFTQIKTEPGTSFSQPCSSTSGSTQTLPDFTSVFSMPQSVAVNNIFIKQEMPSDIPLSSSSQQAQFYQMPLGNGNADLTNLTPSSNSTTAINSLSGVTMSTGNAMSSVLHRHVQAGGPVKQYPHISQGQENFNISGQFYAVPGVNLPPSPPNSQPGSPENQPELINTISPPPSYEATFGLKLVQSSQVPPVPNSLGTLCQGPTVMQTLKYNRRNNPELEKRRIHHCDYPGCTKVYTKSSHLKAHQRTHTGEKPYKCTWDGCDWRFARSDELTRHYRKHTGAKPFKCLACGRCFSRSDHLALHMKRHQN", "length": 438, "header": "tr|A0A8V0YCJ0-1|A0A8V0YCJ0_CHICK Computationally mapped isoform of C2H2-type domain-containing protein OS=Gallus gallus OX=9031 GN=LOC430697 PE=4 SV=1 CANONICAL=A0A8V0YJH4-1" }, "locus": { "chromosome": "4", "start_pos": 11413946, "end_pos": 11398829, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028252.1", "url": "https://www.ensembl.org/id/ENSGALT00010028252.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016185.1", "url": "https://www.ensembl.org/id/ENSGALP00010016185.1" } ] } }, { "isoform_ac": "A0A8V0YJH4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJH4/entry#A0A8V0YJH4-1", "sequence": { "sequence": "MSSGLVLCAPLPDDSSAFTPLKPVTMSGEPGEDTSVFEDIKPPARAPDNPPDLAQLHPMRMEQRMPLTLEGRSEMDKYLSSQLPPIPMIPDKKYRRESASVVDEFFSTEKPNSTPYSVNINVILPDTTHLRTGLYRSPKPMTPFTQIKTEPGTSFSQPCSSTSGSTQTLPDFTSVFSMPQSVAVNNIFIKQEMPSDIPLSSSSQQAQFYQMPLGNGNADLTNLTPSSNSTTAINSLSGVTMSTGNAMSSVLHRHVQAGGPVKQYPHISQGQENFNISGQFYAVPGVNLPPSPPNSQPGSPENQPELINTISPPPSYEATFGLKLVQSSQVPPVPNSLGTLCQGPTVMQTLKYNRRNNPELEKRRIHHCDYPGCTKVYTKSSHLKAHQRTHTGEKPYKCTWDGCDWRFARSDELTRHYRKHTGAKPFKCLACGRCFSRSDHLALHMKRHQN", "length": 450, "header": "tr|A0A8V0YJH4-1|A0A8V0YJH4_CHICK Isoform 1 of C2H2-type domain-containing protein OS=Gallus gallus OX=9031 GN=LOC430697 PE=4 SV=1 CANONICAL=A0A8V0YJH4-1" }, "locus": { "chromosome": "4", "start_pos": 11417681, "end_pos": 11398829, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028267.1", "url": "https://www.ensembl.org/id/ENSGALT00010028267.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016194.1", "url": "https://www.ensembl.org/id/ENSGALP00010016194.1" } ] } }, { "isoform_ac": "E1BZV5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJH4/entry#E1BZV5-1", "sequence": { "sequence": "MEWDQAHLDLQVEGRSEMDKYLSSQLPPIPMIPDKKYRRESASVVDEFFSTEKPNSTPYSVNINVILPDTTHLRTGLYRSPKPMTPFTQIKTEPGTSFSQPCSSTSGSTQTLPDFTSVFSMPQSVAVNNIFIKQEMPSDIPLSSSSQQAQFYQMPLGNGNADLTNLTPSSNSTTAINSLSGVTMSTGNAMSSVLHRHVQAGGPVKQYPHISQGQENFNISGQFYAVPGVNLPPSPPNSQPGSPENQPELINTISPPPSYEATFGLKLVQSSQVPPVPNSLGTLCQGPTVMQTLKYNRRNNPELEKRRIHHCDYPGCTKVYTKSSHLKAHQRTHTGEKPYKCTWDGCDWRFARSDELTRHYRKHTGAKPFKCLACGRCFSRSDHLALHMKRHQN", "length": 393, "header": "tr|E1BZV5-1|E1BZV5_CHICK Computationally mapped isoform of C2H2-type domain-containing protein OS=Gallus gallus OX=9031 GN=LOC430697 PE=4 SV=4 CANONICAL=A0A8V0YJH4-1" }, "locus": { "chromosome": "4", "start_pos": 11407323, "end_pos": 11398829, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028259.1", "url": "https://www.ensembl.org/id/ENSGALT00010028259.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016190.1", "url": "https://www.ensembl.org/id/ENSGALP00010016190.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:430697", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:430697", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJH4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJH4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJH4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJH4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJH4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJH4" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJH4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJH4" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJH4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJH4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 112, "end_pos": 114, "annotation": "n_glycosylation_sequon" }, { "start_pos": 222, "end_pos": 224, "annotation": "n_glycosylation_sequon" }, { "start_pos": 228, "end_pos": 230, "annotation": "n_glycosylation_sequon" }, { "start_pos": 275, "end_pos": 277, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YJH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJH4" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 366, "end_pos": 395, "start_aa": "His", "end_aa": "Pro", 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"id": "PTHR14739", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14739", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14739:SF9", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14739:SF9", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YJI1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJI1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJI1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJI1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YSN0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSN0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YSN0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSN0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YXN2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXN2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YXN2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXN2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEDIELSRSERKITPRNVLSLFWTQLSIATLNARASPKKTVLARNSGPEGPCLESTSLSFSSTPHNERSGDSNSLLCEEAPPEKDEKKDISISDMKLEDKSSKTTAVIEAMTMTVHEKTKLEKSTDDSSYKERIVQEPVITARIQELSVDGQSEHGEAKNTSQDSVQKRSGTMKAVLQSSKSSSCKHLSSAQFKEKVKAVPPHYLGTLKVLEDKHLQKNSTEFDKADSLRAAVFQNWMEKKRTFLLELKRTEKKNAEELRNDAEKKEAVKREEANASFKTWKAMKAREAKKLNEKKKLEKLKEKEAAEQNAERAEAAQKAFEKWKEKKIEYLREQGRQEKQSERIRKKKEEELAAKKKRDSISAVEKWNGKKKECMKQKKAEKILERRKKEIQQAKKDEKDKMAREEYERWLGNIKRRELKKQQKSLQAVHRNEVSFPWIPPGKVTYTKSY", "length": 451, "header": "tr|A0A8V0YJI1-1|A0A8V0YJI1_CHICK Isoform 1 of Microtubule associated protein 9 OS=Gallus gallus OX=9031 GN=MAP9 PE=4 SV=1 CANONICAL=A0A8V0YJI1-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YJI1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJI1/entry#A0A8V0YJI1-1", "sequence": { "sequence": 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"database": "Ensembl Peptide", "id": "ENSGALP00010021090.1", "url": "https://www.ensembl.org/id/ENSGALP00010021090.1" } ] } }, { "isoform_ac": "A0A8V0YXN2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJI1/entry#A0A8V0YXN2-1", "sequence": { "sequence": "MSWDGASAEGPCLESTSLSFSSTPHNERSGDSNSLLCEEAPPEKDEKKDISISDMKLEDKSSKTTAVIEAMTMTVHEKTKLEKSTDDSSYKERIVQEPVITARIQELSVDGQSEHGEAKNTSQDSVQKRSGTMKAVLQSSKSSSCKHLSSAQFKEKVKAVPPHYLGTLKVLEDKHLQKNSTEFDKADSLRAAVFQNWMEKKRTFLLELKRTEKKNAEELRNDAEKKEAVKREEANASFKTWKAMKAREAKKLNEKKKLEKLKEKEAAEQNAERAEAAQKAFEKWKEKKIEYLREQGRQEKQSERIRKKKEEELAAKKKRDSISAVEKWNGKKKECMKQKKAEKILERRKKEIQQAKKDEKDKMAREEYERWLGNIKRRELKKQQKSLQAVHRNEVSFPWIPPGKVTYTKSY", "length": 411, "header": "tr|A0A8V0YXN2-1|A0A8V0YXN2_CHICK Computationally mapped isoform of Microtubule associated protein 9 OS=Gallus gallus OX=9031 GN=MAP9 PE=4 SV=1 CANONICAL=A0A8V0YJI1-1" }, "locus": { "chromosome": "4", "start_pos": 20091337, "end_pos": 20078881, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010036268.1", "url": "https://www.ensembl.org/id/ENSGALT00010036268.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021087.1", "url": "https://www.ensembl.org/id/ENSGALP00010021087.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:422406", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422406", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "regulation of mitotic centrosome separation", "id": "GO:0046602", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046602", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJI1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJI1" } ], "pmid": "" }, { "name": "mitotic spindle assembly", "id": "GO:0090307", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090307", "evidence": [ { "database": 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introns :: single sample supports all introns SAMEA103992290, SAMEA103992559 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000012.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. 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Regulates retrieval of proteins from endosomes to the trans-Golgi network through interaction with the dynein-dynactin complex. Dual effector of RAB4B and RAB14, mediates a cooperative interaction allowing endosomal tethering and fusion. Binds phospholipid vesicles containing phosphatidylinositol 3-phosphate and participates in early endosomal trafficking. In oocytes, self-assembles to form a protein matrix which hold together endolysosomes, autophagosomes and proteasomes and generate non-membrane-bound compartments called endo-lysosomal vesicular assemblies (ELVAs). 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"glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RUFY1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJI6", "locus": { "chromosome": "13", "start_pos": 13197183, "end_pos": 13210628, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010015066", "url": "https://www.ensembl.org/id/ENSGALG00010015066" } ] } } ], "crossref": [ { "id": "A0A8V0YJI6", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YJI6", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15758", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15758", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd17694", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd17694", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "426519", "url": "https://www.ncbi.nlm.nih.gov/gene/426519", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000306", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000306", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004012", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004012", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011011", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011011", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017455", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017455", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037213", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037213", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047330", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047330", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047331", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047331", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047335", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047335", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YJI6", "url": "https://www.orthodb.org/?gene=A0A8V0YJI6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YQW1", "url": "https://www.orthodb.org/?gene=A0A8V0YQW1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YQW6", "url": "https://www.orthodb.org/?gene=A0A8V0YQW6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YR01", "url": "https://www.orthodb.org/?gene=A0A8V0YR01", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45956", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45956", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45956:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45956:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01363", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01363", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02759", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02759", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-1660499", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1660499", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YJI6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJI6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJI6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJI6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQW1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQW1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQW1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQW1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQW6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQW6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQW6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQW6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YR01", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YR01", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YR01-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YR01-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAGERCAAAAAGMKEDFEIIDKTQVPDTAELKNVEKEKEEAKWSAPILSLAKKASENLALSYGSALKSAASVGLISKAVSNDSTAKTTARHHAMEERANLMNMMKLSIKTLIQSALSLGRTLDSDFPPLQQFFVVLEHCLKHGLKAKKTFIGQNKSFFGPLELVEKLCPEASDIATSVKNLPELKTAVGRGRAWLYLALMQKKLADYLKVLLDHKHLLSEFYEPDALMMEEEGAVIVGLLVGLNVIDANLCLKGEDLDSQVGVIDFSLYLKETQDSDGKQEVSSQSVISCFTIRDGDITAVLDQKHYVEELNRHLSCTVTDLQNKIDCLEKTNSKLQEELAAATDRIGSLQEEQQQLKQQNELIRERSEKSVEVTKEDTKVELDTYRQSRQGLDEMYSDVWKQLKEEKKIRLELEKELELQIGMKTEMEIAMKLLEKDTHEKQDTLVALRQQLEEVKAINLQMFHKSQNAECSLQQKTEAISSFEGKTNEMMSAMKQMEERLQHAEKARQAAEERCNKMKQELASRLDTCRQQMSQLDSKCSTLEKELKSEKEQRQTLQRELHREKDATSLLKTELEQMEGLKKELRKLQDEKQQLEKVCEEQEQALQEMGLHLSQSKLKMEDIKEVNKALKGHTWLKDDEATHCKQCEKEFSISRRKHHCRNCGDIFCNACSSNELALPSYPKPVRVCDTCHTLLLQRCSSNSS", "length": 706, "header": "tr|A0A8V0YJI6-1|A0A8V0YJI6_CHICK Isoform 1 of RUN and FYVE domain-containing protein 1 OS=Gallus gallus OX=9031 GN=RUFY1 PE=1 SV=1 CANONICAL=A0A8V0YJI6-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YJI6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJI6/entry#A0A8V0YJI6-1", "sequence": { "sequence": "MAAGERCAAAAAGMKEDFEIIDKTQVPDTAELKNVEKEKEEAKWSAPILSLAKKASENLALSYGSALKSAASVGLISKAVSNDSTAKTTARHHAMEERANLMNMMKLSIKTLIQSALSLGRTLDSDFPPLQQFFVVLEHCLKHGLKAKKTFIGQNKSFFGPLELVEKLCPEASDIATSVKNLPELKTAVGRGRAWLYLALMQKKLADYLKVLLDHKHLLSEFYEPDALMMEEEGAVIVGLLVGLNVIDANLCLKGEDLDSQVGVIDFSLYLKETQDSDGKQEVSSQSVISCFTIRDGDITAVLDQKHYVEELNRHLSCTVTDLQNKIDCLEKTNSKLQEELAAATDRIGSLQEEQQQLKQQNELIRERSEKSVEVTKEDTKVELDTYRQSRQGLDEMYSDVWKQLKEEKKIRLELEKELELQIGMKTEMEIAMKLLEKDTHEKQDTLVALRQQLEEVKAINLQMFHKSQNAECSLQQKTEAISSFEGKTNEMMSAMKQMEERLQHAEKARQAAEERCNKMKQELASRLDTCRQQMSQLDSKCSTLEKELKSEKEQRQTLQRELHREKDATSLLKTELEQMEGLKKELRKLQDEKQQLEKVCEEQEQALQEMGLHLSQSKLKMEDIKEVNKALKGHTWLKDDEATHCKQCEKEFSISRRKHHCRNCGDIFCNACSSNELALPSYPKPVRVCDTCHTLLLQRCSSNSS", "length": 706, "header": "tr|A0A8V0YJI6-1|A0A8V0YJI6_CHICK Isoform 1 of RUN and FYVE domain-containing protein 1 OS=Gallus gallus OX=9031 GN=RUFY1 PE=1 SV=1 CANONICAL=A0A8V0YJI6-1" }, "locus": { "chromosome": "13", "start_pos": 13210603, "end_pos": 13197721, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010036273.1", "url": "https://www.ensembl.org/id/ENSGALT00010036273.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021092.1", "url": "https://www.ensembl.org/id/ENSGALP00010021092.1" } ] } }, { "isoform_ac": "A0A8V0YQW1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJI6/entry#A0A8V0YQW1-1", "sequence": { "sequence": "MQSAGQRRGKHIINPFSAIEETVLLGWEGRRCKLKECKSRKTVLNTKRWRTVTFSSWYAETHFKVCGAVYAARHHAMEERANLMNMMKLSIKTLIQSALSLGRTLDSDFPPLQQFFVVLEHCLKHGLKAKKTFIGQNKSFFGPLELVEKLCPEASDIATSVKNLPELKTAVGRGRAWLYLALMQKKLADYLKVLLDHKHLLSEFYEPDALMMEEEGAVIVGLLVGLNVIDANLCLKGEDLDSQVGVIDFSLYLKETQDSDGKQDGDITAVLDQKHYVEELNRHLSCTVTDLQNKIDCLEKTNSKLQEELAAATDRIGSLQEEQQQLKQQNELIRERSEKSVEVTKEDTKVELDTYRQSRQGLDEMYSDVWKQLKEEKKIRLELEKELELQIGMKTEMEIAMKLLEKDTHEKQDTLVALRQQLEEVKAINLQMFHKSQNAECSLQQKTEAISSFEGKTNEMMSAMKQMEERLQHAEKARQAAEERCNKMKQELASRLDTCRQQMSQLDSKCSTLEKELKSEKEQRQTLQRELHREKDATSLLKTELEQMEGLKKELRKLQDEKQQLEKVCEEQEQALQEMGLHLSQSKLKMEDIKEVNKALKGHTWLKDDEATHCKQCEKEFSISRRKHHCRNCGDIFCNACSSNELALPSYPKPVRVCDTCHTLLLQRCSSNSS", "length": 674, "header": "tr|A0A8V0YQW1-1|A0A8V0YQW1_CHICK Computationally mapped isoform of RUN and FYVE domain-containing protein 1 OS=Gallus gallus OX=9031 GN=RUFY1 PE=1 SV=1 CANONICAL=A0A8V0YJI6-1" }, "locus": { "chromosome": "13", "start_pos": 13209191, "end_pos": 13197721, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010036261.1", "url": "https://www.ensembl.org/id/ENSGALT00010036261.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021083.1", "url": "https://www.ensembl.org/id/ENSGALP00010021083.1" } ] } }, { "isoform_ac": "A0A8V0YQW6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJI6/entry#A0A8V0YQW6-1", "sequence": { "sequence": "MAAGERCAAAAAGMKEDFEIIDKTQVPDTAELKNVEKEKEEAKWSAPILSLAKKASENLALSYGSALKSAASVGLISKAVSNDSTAKTTARHHAMEERANLMNMMKLSIKTLIQSALSLGRTLDSDFPPLQQFFVVLEHCLKHGLKAKKTFIGQNKSFFGPLELVEKLCPEASDIATSVKNLPELKTAVGRGRAWLYLALMQKKLADYLKVLLDHKHLLSEFYEPDALMMEEEGAVIVGLLVGLNVIDANLCLKGEDLDSQVGVIDFSLYLKETQDSDGKQDGDITAVLDQKHYVEELNRHLSCTVTDLQNKIDCLEKTNSKLQEELAAATDRIGSLQEEQQQLKQQNELIRERSEKSVEVTKEDTKVELDTYRQSRQGLDEMYSDVWKQLKEEKKIRLELEKELELQIGMKTEMEIAMKLLEKDTHEKQDTLVALRQQLEEVKAINLQMFHKSQNAECSLQQKTEAISSFEGKTNEMMSAMKQMEERLQHAEKARQAAEERCNKMKQELASRLDTCRQQMSQLDSKCSTLEKELKSEKEQRQTLQRELHREKDATSLLKTELEQMEGLKKLRKLQDEKQQLEKVCEEQEQALQEMGLHLSQSKLKMEDIKEVNKALKGHTWLKDDEATHCKQCEKEFSISRRKHHCRNCGDIFCNACSSNELALPSYPKPVRVCDTCHTLLLQRCSSNSS", "length": 691, "header": "tr|A0A8V0YQW6-1|A0A8V0YQW6_CHICK Computationally mapped isoform of RUN and FYVE domain-containing protein 1 OS=Gallus gallus OX=9031 GN=RUFY1 PE=1 SV=1 CANONICAL=A0A8V0YJI6-1" }, "locus": { "chromosome": "13", "start_pos": 13210603, "end_pos": 13197721, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010036269.1", "url": "https://www.ensembl.org/id/ENSGALT00010036269.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021088.1", "url": "https://www.ensembl.org/id/ENSGALP00010021088.1" } ] } }, { "isoform_ac": "A0A8V0YR01-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJI6/entry#A0A8V0YR01-1", "sequence": { "sequence": "MAPGARGPRSISREFRIVGGCCCCAARHHAMEERANLMNMMKLSIKTLIQSALSLGRTLDSDFPPLQQFFVVLEHCLKHGLKAKKTFIGQNKSFFGPLELVEKLCPEASDIATSVKNLPELKTAVGRGRAWLYLALMQKKLADYLKVLLDHKHLLSEFYEPDALMMEEEGAVIVGLLVGLNVIDANLCLKGEDLDSQVGVIDFSLYLKETQDSDGKQDGDITAVLDQKHYVEELNRHLSCTVTDLQNKIDCLEKTNSKLQEELAAATDRIGSLQEEQQQLKQQNELIRERSEKSVEVTKEDTKVELDTYRQSRQGLDEMYSDVWKQLKEEKKIRLELEKELELQIGMKTEMEIAMKLLEKDTHEKQDTLVALRQQLEEVKAINLQMFHKSQNAECSLQQKTEAISSFEGKTNEMMSAMKQMEERLQHAEKARQAAEERCNKMKQELASRLDTCRQQMSQLDSKCSTLEKELKSEKEQRQTLQRELHREKDATSLLKTELEQMEGLKKELRKLQDEKQQLEKVCEEQEQALQEMGLHLSQSKLKMEDIKEVNKALKGHTWLKDDEATHCKQCEKEFSISRRKHHCRNCGDIFCNACSSNELALPSYPKPVRVCDTCHTLLLQRCSSNSS", "length": 628, "header": "tr|A0A8V0YR01-1|A0A8V0YR01_CHICK Computationally mapped isoform of RUN and FYVE domain-containing protein 1 OS=Gallus gallus OX=9031 GN=RUFY1 PE=1 SV=1 CANONICAL=A0A8V0YJI6-1" }, "locus": { "chromosome": "13", "start_pos": 13207806, "end_pos": 13197721, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010036256.1", "url": "https://www.ensembl.org/id/ENSGALT00010036256.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021080.1", "url": "https://www.ensembl.org/id/ENSGALP00010021080.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-1660499", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1660499", "resource": "Reactome", "description": "Synthesis of PIPs at the plasma membrane" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJI6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJI6" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJI6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJI6" } ], "pmid": "" }, { "name": "early endosome membrane", "id": "GO:0031901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031901", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJI6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJI6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "endocytosis", "id": "GO:0006897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006897", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJI6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJI6" } ], "pmid": "" }, { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJI6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJI6" } ], "pmid": "" }, { "name": "regulation of endocytosis", "id": "GO:0030100", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030100", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJI6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJI6" } ], "pmid": "" }, { "name": "endosomal vesicle fusion", "id": "GO:0034058", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034058", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJI6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJI6" } ], "pmid": "" }, { "name": "early endosome to Golgi transport", "id": "GO:0034498", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034498", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJI6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJI6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJI6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJI6" } ], "pmid": "" }, { "name": "SH3 domain binding", "id": "GO:0017124", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017124", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJI6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJI6" } ], "pmid": "" }, { "name": "protein-macromolecule adaptor activity", "id": "GO:0030674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030674", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJI6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJI6" } ], "pmid": "" }, { "name": "lipid binding", "id": "GO:0008289", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008289", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJI6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJI6" } ], "pmid": "" }, { "name": "SH2 domain binding", "id": "GO:0042169", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042169", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJI6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJI6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 155, "end_pos": 157, "annotation": "n_glycosylation_sequon" }, { "start_pos": 704, "end_pos": 706, "annotation": "n_glycosylation_sequon" }, { "start_pos": 82, "end_pos": 84, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YJI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJI6" }, { "id": "PS50178", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50178" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "FYVE-type", "eco_id": "ECO_0000259", "start_pos": 640, "end_pos": 698, "start_aa": "Asp", "end_aa": "Leu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0YJI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJI6" }, { "id": "PS50826", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50826" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RUN", "eco_id": "ECO_0000259", "start_pos": 124, "end_pos": 256, "start_aa": "Asp", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 155, "end_pos": 157 }, { "start_pos": 704, "end_pos": 706 }, { "start_pos": 82, "end_pos": 84 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", 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"field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YJL5-1", "uniprot_ac": "A0A8V0YJL5", "uniprot_id": "A0A8V0YJL5_CHICK", "mass": { "chemical_mass": 17920.0, "monoisotopic_mass": 17920.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Uncharacterized protein", "type": "synonym", "evidence": [ { "id": "A0A8V0YJL5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJL5/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJL5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJL5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJL5", "locus": {} } ], "crossref": [ { "id": "A0A8V0YJL5", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YJL5", "database": "AlphaFoldDB", "categories": [] }, { "id": "A0A8V0YJL5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJL5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJL5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJL5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MHSIILGSISVQKIADFKELQNMVLGFMFLNYKYCWASALHLLKSSCSPAVQIKIQEPVVLPKSWCRYPSSSPTDPVWDIAGIHPLPSALVTPQFPSLPVTFVLLQDTKAHFEMQQPSPSIPPAHPDIQLKSLPFYNVLDVLLLNKPTSLKIITLTVCALK", "length": 161, "header": "tr|A0A8V0YJL5-1|A0A8V0YJL5_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0YJL5-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YJL5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJL5/entry#A0A8V0YJL5-1", "sequence": { "sequence": "MHSIILGSISVQKIADFKELQNMVLGFMFLNYKYCWASALHLLKSSCSPAVQIKIQEPVVLPKSWCRYPSSSPTDPVWDIAGIHPLPSALVTPQFPSLPVTFVLLQDTKAHFEMQQPSPSIPPAHPDIQLKSLPFYNVLDVLLLNKPTSLKIITLTVCALK", "length": 161, "header": "tr|A0A8V0YJL5-1|A0A8V0YJL5_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0YJL5-1" }, "locus": { "chromosome": "Z", "start_pos": 8115002, "end_pos": 8113325, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028343.1", "url": "https://www.ensembl.org/id/ENSGALT00010028343.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016241.1", "url": "https://www.ensembl.org/id/ENSGALP00010016241.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YJM1-1", "uniprot_ac": "A0A8V0YJM1", "uniprot_id": "A0A8V0YJM1_CHICK", "mass": { "chemical_mass": 125908.0, "monoisotopic_mass": 125908.0 }, "refseq": { "ac": "XP_025011777", "name": "DENN domain-containing protein 2A isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025011777" }, "gene_names": [ { "name": "DENND2A", "type": "recommended", "evidence": [ { "id": "A0A8V0YJM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJM1" } ] }, { "name": "DENND2A", "type": "synonym", "evidence": [ { "id": "XP_025011777", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025011777" } ] } ], "protein_names": [ { "name": "DENN domain containing 2A", "type": "synonym", "evidence": [ { "id": "A0A8V0YJM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJM1/entry#names_and_taxonomy" } ] }, { "name": "DENN domain-containing protein 2A isoform X3", "type": "synonym", "evidence": [ { "id": "XP_025011777", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025011777" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_025011777", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025011777" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJM1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJM1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "DENND2A", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJM1", "locus": { "chromosome": "1", "start_pos": 56877487, "end_pos": 56934921, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013381", "url": "https://www.ensembl.org/id/ENSGALG00010013381" } ] } } ], "crossref": [ { "id": "A0A8V0YJM1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YJM1", "database": "AlphaFoldDB", "categories": [] }, { "id": "418115", "url": "https://www.ncbi.nlm.nih.gov/gene/418115", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001194", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001194", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005112", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005112", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005113", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005113", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037516", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037516", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043153", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043153", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051942", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051942", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:418115", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418115", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YJL6", "url": "https://www.orthodb.org/?gene=A0A8V0YJL6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YJM1", "url": "https://www.orthodb.org/?gene=A0A8V0YJM1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YK97", "url": "https://www.orthodb.org/?gene=A0A8V0YK97", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15288", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15288", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15288:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15288:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02141", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02141", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF03455", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03455", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF03456", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03456", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-8876198", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8876198", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_025011777", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025011777", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YJL6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJL6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJL6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJL6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJM1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJM1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJM1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJM1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YK97", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK97", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YK97-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK97-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAGRAGSLQPRVRRPPARRRATPPCRGTAPRRRRGRIKLADKNSTAAVKELGRLLCGFSSERCSEGASVTLSLTPEAEPVSCVVKNPLGALENLMLDPRLDCFQQNMLSPKMIISDPSVDLNVKESSRIIRKQIGGTQSTRTPGKIGLRNKSFSIKDKISEWEGKKEMQSAPRREEEQGTKEERKIPCVVEKTSGEALTSRKVETKRLMNWELECKGASKENERKAGTPKGTEQGAQRKGEVEKDEEVQSSLGKCKEVKGGKWEVQKENLSVLSQVKKLEQALKDGSAELQPQLPGTYYSPQCLQEKSAQGHAAPEGHESICGTELNKRLLGLDSEISEPIFGTLEEVRTSHVKSKDCTTENVYTEPGVPEKKPFINPLPKPRRTFKHEGEEDWVPAARNKRNLPPLPSIPPPPLPSSPPPSAVSRRLWSGKHKNNADHRKSYEFEDLLQSSSENGRVDWYAQTKLALTRTLSEENVYEDILDPPSKENPYEDIETNSRCLGKKCVLTFPASPTSSVPGTPTKLLSKPTFFRQNSERRSFKLPDIRKLSRDGTGSPSKISPPSTPSSPDDTFFSLGDPQNGKRRRKIPKLVLKINAIYEARRGKKRVKRLSQSTESNSGKVTDENSESDSDTEEKLKAHSQRLVHVKSRLKQTPRYQTLERDLIEYQERQLFEYFVVVSLHKKQAGAAYIPEVTQQFPLKLERSFKFMREAEDQLKAIPQFCFPDAKDWAPIHQFASETFSFVLTGEDGSRRFGYCRRLLPSGKGKRLPEVYCIVSRLGCFNLFSKILDEVEKRRGISPALVQPLMRSVMEAPFPALGRTITVKNFLPGSGTEVIELRRPLDSRLEHVDFESLFASLSVRHLSRVFASLLLERRVIFIADKLSTLSKCCHATVALLYPFTWQHTYIPVLPPSMIDIVCSPTPFLIGLLSSSLPRLKELPVEEVLVVDLVNNRFLRQMEDEDSILPRKLQAALEHILEQRNELASDKEEGSVNGKQETSPLNEVVSEAFVRFFVEIVGHYSLFLTPNEREERTLQREAFRKSVSSKSLRRFLEVFMETQMFGGFIQEREMRKQGVRGLFEVRAQEYLETLPSGEQSGVNRFLKGLGSKMKFLHKK", "length": 1114, "header": "tr|A0A8V0YJM1-1|A0A8V0YJM1_CHICK Isoform 1 of DENN domain containing 2A OS=Gallus gallus OX=9031 GN=DENND2A PE=4 SV=1 CANONICAL=A0A8V0YJM1-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YJL6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJM1/entry#A0A8V0YJL6-1", "sequence": { "sequence": 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"length": 1091, "header": "tr|A0A8V0YJL6-1|A0A8V0YJM1_CHICK Computationally mapped isoform of DENN domain containing 2A OS=Gallus gallus OX=9031 GN=DENND2A PE=4 SV=1 CANONICAL=A0A8V0YJM1-1" }, "locus": { "chromosome": "1", "start_pos": 56915436, "end_pos": 56878149, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032215.1", "url": "https://www.ensembl.org/id/ENSGALT00010032215.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019005.1", "url": "https://www.ensembl.org/id/ENSGALP00010019005.1" } ] } }, { "isoform_ac": "A0A8V0YJM1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJM1/entry#A0A8V0YJM1-1", "sequence": { "sequence": "MAGRAGSLQPRVRRPPARRRATPPCRGTAPRRRRGRIKLADKNSTAAVKELGRLLCGFSSERCSEGASVTLSLTPEAEPVSCVVKNPLGALENLMLDPRLDCFQQNMLSPKMIISDPSVDLNVKESSRIIRKQIGGTQSTRTPGKIGLRNKSFSIKDKISEWEGKKEMQSAPRREEEQGTKEERKIPCVVEKTSGEALTSRKVETKRLMNWELECKGASKENERKAGTPKGTEQGAQRKGEVEKDEEVQSSLGKCKEVKGGKWEVQKENLSVLSQVKKLEQALKDGSAELQPQLPGTYYSPQCLQEKSAQGHAAPEGHESICGTELNKRLLGLDSEISEPIFGTLEEVRTSHVKSKDCTTENVYTEPGVPEKKPFINPLPKPRRTFKHEGEEDWVPAARNKRNLPPLPSIPPPPLPSSPPPSAVSRRLWSGKHKNNADHRKSYEFEDLLQSSSENGRVDWYAQTKLALTRTLSEENVYEDILDPPSKENPYEDIETNSRCLGKKCVLTFPASPTSSVPGTPTKLLSKPTFFRQNSERRSFKLPDIRKLSRDGTGSPSKISPPSTPSSPDDTFFSLGDPQNGKRRRKIPKLVLKINAIYEARRGKKRVKRLSQSTESNSGKVTDENSESDSDTEEKLKAHSQRLVHVKSRLKQTPRYQTLERDLIEYQERQLFEYFVVVSLHKKQAGAAYIPEVTQQFPLKLERSFKFMREAEDQLKAIPQFCFPDAKDWAPIHQFASETFSFVLTGEDGSRRFGYCRRLLPSGKGKRLPEVYCIVSRLGCFNLFSKILDEVEKRRGISPALVQPLMRSVMEAPFPALGRTITVKNFLPGSGTEVIELRRPLDSRLEHVDFESLFASLSVRHLSRVFASLLLERRVIFIADKLSTLSKCCHATVALLYPFTWQHTYIPVLPPSMIDIVCSPTPFLIGLLSSSLPRLKELPVEEVLVVDLVNNRFLRQMEDEDSILPRKLQAALEHILEQRNELASDKEEGSVNGKQETSPLNEVVSEAFVRFFVEIVGHYSLFLTPNEREERTLQREAFRKSVSSKSLRRFLEVFMETQMFGGFIQEREMRKQGVRGLFEVRAQEYLETLPSGEQSGVNRFLKGLGSKMKFLHKK", "length": 1114, "header": "tr|A0A8V0YJM1-1|A0A8V0YJM1_CHICK Isoform 1 of DENN domain containing 2A OS=Gallus gallus OX=9031 GN=DENND2A PE=4 SV=1 CANONICAL=A0A8V0YJM1-1" }, "locus": { "chromosome": "1", "start_pos": 56934890, "end_pos": 56878149, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032220.1", "url": "https://www.ensembl.org/id/ENSGALT00010032220.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019010.1", "url": "https://www.ensembl.org/id/ENSGALP00010019010.1" } ] } }, { "isoform_ac": "A0A8V0YK97-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJM1/entry#A0A8V0YK97-1", "sequence": { "sequence": "MMTASKAADASSRSESSVCKSAERIKLADKNSTAAVKELGRLLCGFSSERCSEGASVTLSLTPEAEPVSCVVKNPLGALENLMLDPRLDCFQQNMLSPKMIISDPSVDLNVKESSRIIRKQIGGTQSTRTPGKIGLRNKSFSIKDKISEWEGKKEMQSAPRREEEQGTKEERKIPCVVEKTSGEALTSRKVETKRLMNWELECKGASKENERKAGTPKGTEQGAQRKGEVEKDEEVQSSLGKCKEVKGGKWEVQKENLSVLSQVKKLEQALKDGSAELQPQLPGTYYSPQCLQEKSAQGHAAPEGHESICGTELNKRLLGLDSEISEPIFGTLEEVRTSHVKSKDCTTENVYTEPGVPEKKPFINPLPKPRRTFKHEGEEDWVPAARNKRNLPPLPSIPPPPLPSSPPPSAVSRRLWSGKHKNNADHRKSYEFEDLLQSSSENGRVDWYAQTKLALTRTLSEENVYEDILDPPSKENPYEDIETNSRCLGKKCVLTFPASPTSSVPGTPTKLLSKPTFFRQNSERRSFKLPDIRKLSRDGTGSPSKISPPSTPSSPDDTFFSLGDPQNGKRRRKIPKLVLKINAIYEARRGKKRVKRLSQSTESNSGKVTDENSESDSDTEEKLKAHSQRLVHVKSRLKQTPRYQTLERDLIEYQERQLFEYFVVVSLHKKQAGAAYIPEVTQQFPLKLERSFKFMREAEDQLKAIPQFCFPDAKDWAPIHQFASFSFCSETFSFVLTGEDGSRRFGYCRRLLPSGKGKRLPEVYCIVSRLGCFNLFSKILDEVEKRRGISPALVQPLMRSVMEAPFPALGRTITVKNFLPGSGTEVIELRRPLDSRLEHVDFESLFASLSVRHLSRVFASLLLERRVIFIADKLSTLSKCCHATVALLYPFTWQHTYIPVLPPSMIDIVCSPTPFLIGLLSSSLPRLKELPVEEVLVVDLVNNRFLRQMEDEDSILPRKLQAALEHILEQRNELASDKEEGSVNGKQETSPLNEVVSEAFVRFFVEIVGHYSLFLTPNEREERTLQREAFRKSVSSKSLRRFLEVFMETQMFGGFIQEREMRKQGVRGLFEVRAQEYLETLPSGEQSGVNRFLKGLGSKMKFLHKK", "length": 1107, "header": "tr|A0A8V0YK97-1|A0A8V0YK97_CHICK Computationally mapped isoform of DENN domain containing 2A OS=Gallus gallus OX=9031 GN=DENND2A PE=4 SV=1 CANONICAL=A0A8V0YJM1-1" }, "locus": { "chromosome": "1", "start_pos": 56915436, "end_pos": 56878149, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032218.1", "url": "https://www.ensembl.org/id/ENSGALT00010032218.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019008.1", "url": "https://www.ensembl.org/id/ENSGALP00010019008.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 564, "start_aa": "Thr", "end_pos": 564, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr564", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:418115", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418115", "resource": "KEGG Pathway" }, { "id": "R-GGA-8876198", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8876198", "resource": "Reactome", "description": "RAB GEFs exchange GTP for GDP on RABs" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "guanyl-nucleotide exchange factor activity", "id": "GO:0005085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005085", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJM1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJM1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJM1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJM1" } ], "pmid": "" }, { "name": "actin cytoskeleton", "id": "GO:0015629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015629", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJM1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJM1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "retrograde transport, endosome to Golgi", "id": "GO:0042147", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042147", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJM1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJM1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 150, "end_pos": 152, "annotation": "n_glycosylation_sequon" }, { "start_pos": 269, "end_pos": 271, "annotation": "n_glycosylation_sequon" }, { "start_pos": 43, "end_pos": 45, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YJM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJM1" }, { "id": "PS50211", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50211" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "UDENN", "eco_id": "ECO_0000259", "start_pos": 673, "end_pos": 1074, "start_aa": "Glu", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 564 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 150, "end_pos": 152 }, { "start_pos": 269, "end_pos": 271 }, { "start_pos": 43, "end_pos": 45 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", 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"phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YJL9-1", "uniprot_ac": "A0A8V0YJL9", "uniprot_id": "A0A8V0YJL9_CHICK", "mass": { "chemical_mass": 48222.0, "monoisotopic_mass": 48222.0 }, "refseq": {}, "gene_names": [ { "name": "KLF8", "type": "recommended", "evidence": [ { "id": "A0A8V0YJL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJL9" } ] } ], "protein_names": [ { "name": "KLF transcription factor 8", "type": "synonym", "evidence": [ { "id": "A0A8V0YJL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJL9/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJL9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJL9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "KLF8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJL9", "locus": { "chromosome": "4", "start_pos": 11420790, "end_pos": 11428004, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010011866", "url": "https://www.ensembl.org/id/ENSGALG00010011866" } ] } } ], "crossref": [ { "id": "A0A8V0YJL9", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YJL9", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd21440", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd21440", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "101749773", "url": "https://www.ncbi.nlm.nih.gov/gene/101749773", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:101749773", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:101749773", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "KMTSPPF", "url": "https://omabrowser.org/oma/group/KMTSPPF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y6G3", "url": "https://www.orthodb.org/?gene=A0A8V0Y6G3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YCN7", "url": "https://www.orthodb.org/?gene=A0A8V0YCN7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YJL9", "url": "https://www.orthodb.org/?gene=A0A8V0YJL9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23235", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23235", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23235:SF46", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23235:SF46", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0Y6G3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y6G3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y6G3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y6G3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YCN7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCN7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YCN7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCN7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJL9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJL9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJL9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJL9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPRMEPSVLLVPSKRGLWIWSVIQSSTGPCSKMVGTDPLCQAPYGCMNSLAQLDCGLPTHGCFHRASSCPILPFLCPTQPSSCQGRVLLGLKHDGAVPWSSWVKATEGTLEDHHVFRRTGQSQGSAVFWQAGGSGRGKAAPRMSSSSLLAEAPLEPPVLLSDIKTEPPEELLASDCSQPQAEPVDLSLNKSKAPPPPPPVQSSPLLVAPPVPASTISIASSGLGTTSAIPAVLSPGSILASSQGSGGQQILHVIHTIPSVNLPSKMGNLQTIPVVVQSLPVVYTTMPTDGVTAITVPLIGGDGKNTGSVKMDPGAMYPMDMPSDSEDSASESGPAPFQDLQRESATPRLPRSDSPDLKKRRIHQCDFEGCNKVYTKSSHLKAHRRIHTGEKPYKCTWEGCTWKFARSDELTRHFRKHTGIKPFRCSDCDRSFSRSDHLALHRRRHIMM", "length": 448, "header": "tr|A0A8V0YJL9-1|A0A8V0YJL9_CHICK Isoform 1 of KLF transcription factor 8 OS=Gallus gallus OX=9031 GN=KLF8 PE=4 SV=1 CANONICAL=A0A8V0YJL9-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Y6G3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJL9/entry#A0A8V0Y6G3-1", "sequence": { "sequence": "MHCEEARGKSALTPLCSPQFWQAGGSGRGKAAPRMSSSSLLAEAPLEPPVLLSDIKTEPPEELLASDCSQPQAEPVDLSLNKSKAPPPPPPVQSSPLLVAPPVPASTISIASSGLGTTSAIPAVLSPGSILASSQGSGGQQILHVIHTIPSVNLPSKMGNLQTIPVVVQSLPVVYTTMPTDGVTAITVPLIGGDGKNTGSVKMDPGAMYPMDMPSDSEDSASESGPAPFQDLQRESATPRLPRSDSPDLKKRRIHQCDFEGCNKVYTKSSHLKAHRRIHTGEKPYKCTWEGCTWKFARSDELTRHFRKHTGIKPFRCSDCDRSFSRSDHLALHRRRHIMM", "length": 340, "header": "tr|A0A8V0Y6G3-1|A0A8V0Y6G3_CHICK Computationally mapped isoform of KLF transcription factor 8 OS=Gallus gallus OX=9031 GN=KLF8 PE=4 SV=1 CANONICAL=A0A8V0YJL9-1" }, "locus": { "chromosome": "4", "start_pos": 11426369, "end_pos": 11421347, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028349.1", "url": "https://www.ensembl.org/id/ENSGALT00010028349.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016245.1", "url": "https://www.ensembl.org/id/ENSGALP00010016245.1" } ] } }, { "isoform_ac": "A0A8V0YCN7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJL9/entry#A0A8V0YCN7-1", "sequence": { "sequence": "MILPAEGMSAAHSRRSPPREAWRFWQAGGSGRGKAAPRMSSSSLLAEAPLEPPVLLSDIKTEPPEELLASDCSQPQAEPVDLSLNKSKAPPPPPPVQSSPLLVAPPVPASTISIASSGLGTTSAIPAVLSPGSILASSQGSGGQQILHVIHTIPSVNLPSKMGNLQTIPVVVQSLPVVYTTMPTDGVTAITVPLIGGDGKNTGSVKMDPGAMYPMDMPSDSEDSASESGPAPFQDLQRESATPRLPRSDSPDLKKRRIHQCDFEGCNKVYTKSSHLKAHRRIHTGEKPYKCTWEGCTWKFARSDELTRHFRKHTGIKPFRCSDCDRSFSRSDHLALHRRRHIMM", "length": 344, "header": "tr|A0A8V0YCN7-1|A0A8V0YCN7_CHICK Computationally mapped isoform of KLF transcription factor 8 OS=Gallus gallus OX=9031 GN=KLF8 PE=4 SV=1 CANONICAL=A0A8V0YJL9-1" }, "locus": { "chromosome": "4", "start_pos": 11424876, "end_pos": 11421347, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028346.1", "url": "https://www.ensembl.org/id/ENSGALT00010028346.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016242.1", "url": "https://www.ensembl.org/id/ENSGALP00010016242.1" } ] } }, { "isoform_ac": "A0A8V0YJL9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJL9/entry#A0A8V0YJL9-1", "sequence": { "sequence": "MPRMEPSVLLVPSKRGLWIWSVIQSSTGPCSKMVGTDPLCQAPYGCMNSLAQLDCGLPTHGCFHRASSCPILPFLCPTQPSSCQGRVLLGLKHDGAVPWSSWVKATEGTLEDHHVFRRTGQSQGSAVFWQAGGSGRGKAAPRMSSSSLLAEAPLEPPVLLSDIKTEPPEELLASDCSQPQAEPVDLSLNKSKAPPPPPPVQSSPLLVAPPVPASTISIASSGLGTTSAIPAVLSPGSILASSQGSGGQQILHVIHTIPSVNLPSKMGNLQTIPVVVQSLPVVYTTMPTDGVTAITVPLIGGDGKNTGSVKMDPGAMYPMDMPSDSEDSASESGPAPFQDLQRESATPRLPRSDSPDLKKRRIHQCDFEGCNKVYTKSSHLKAHRRIHTGEKPYKCTWEGCTWKFARSDELTRHFRKHTGIKPFRCSDCDRSFSRSDHLALHRRRHIMM", "length": 448, "header": "tr|A0A8V0YJL9-1|A0A8V0YJL9_CHICK Isoform 1 of KLF transcription factor 8 OS=Gallus gallus OX=9031 GN=KLF8 PE=4 SV=1 CANONICAL=A0A8V0YJL9-1" }, "locus": { "chromosome": "4", "start_pos": 11427805, "end_pos": 11421347, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028350.1", "url": "https://www.ensembl.org/id/ENSGALT00010028350.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016246.1", "url": "https://www.ensembl.org/id/ENSGALP00010016246.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:101749773", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:101749773", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0AAA9T3N2-1", "protein_name": "KLF transcription factor 8", "gene_name": "KLF8", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGDMDQLINNWEVQLNSEGGSMHMFKQVTGPVQIRDSLKRADRGNMTSPPLLDANSMKNPALLNDIKIEPPEELLANDFNLPQVEPVDLSFHKPKAPLQPASMLQSPIRSPKPQPASQTLVVSTSTSDTGSSASIRTVLTPGSILASSQGTGGHQILHVIHTIPSVNLPNKMGSLKAIPVVVQSLPMVYTTLPADGNPAAITVPLIGGDGKNVGSVKVEPTSLSPLEIPSDNEENAIESGSLQGIQGLQQEPAAMTQMQEESLDLKRRRIHQCDFAGCSKVYTKSSHLKAHRRIHTGEKPYKCTWDGCSWKFARSDELTRHFRKHTGIKPFRCTDCNRSFSRSDHLSLHRRRHDTV", "length": 356 }, "evidence": [ { "id": "A0A8V0YJL9", "url": "https://omabrowser.org/oma/group/A0A8V0YJL9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0ABK0M341-1", "protein_name": "KLF transcription factor 8", "gene_name": "Klf8", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDKFINNMDVRIKTESDSMEVFKQVTGPVPTRDPSVRGDRRNMTSPPFLAASPMENPALFNDIKIEPPEELLESDFNTPQVEPVDLSFHKPKAPLQPASMLQAPIRPPKPPTAPQAIMVSTSADTVTSAAIPTVLTPGSILASSQGTGGQPILHVIHTIPSVSLPNKMSGLKTIPLVVQSLPMVYTSLPADGSPAAITVPLIGGDGKSAGSVKVDPASMCPLEFPSDSDESAIESGSSALQSLQGFHHEPATMVHMQGEESLDLKRRRIHQCDFAGCSKVYTKSSHLKAHRRIHTGEKPYKCTWDGCSWKFARSDELTRHFRKHTGIKPFRCTDCNRSFSRSDHLSLHRRRHDTM", "length": 355 }, "evidence": [ { "id": "A0A8V0YJL9", "url": "https://omabrowser.org/oma/group/A0A8V0YJL9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1RTR0-1", "protein_name": "KLF transcription factor 8", "gene_name": "KLF8", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGDMDQLINNLEVQLNSETGSMHVFKQVTGSVQIRDSLKTTGRGDMTSPPLLDINPMENPALLNDIKIEPPEELLANDFNLPQVEPVDLSFHKPKAPLQPASMLQAPIRPPKPEPVSQTLVESTSTSNTGTSANIPTVLTSGSILASSQGTGGQQILHVIHTIPSVSLPNKMSGLKAIPVVVQSLPMVYTTLPADGGPAAITVPLIGGDGKNAGSVKVDPTSMSPLEIPSDSEENAIESGSSALQGIQGLQQEPAVMTQMQGEESLDLKRRRIHQCDFAGCSKVYTKSSHLKAHRRIHTGEKPYKCTWDGCSWKFARSDELTRHFRKHTGIKPFRCADCNRSFSRSDHLSLHRRRHDTM", "length": 359 }, "evidence": [ { "id": "A0A8V0YJL9", "url": "https://omabrowser.org/oma/group/A0A8V0YJL9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3HWU8-1", "protein_name": "Krueppel-like factor 8", "gene_name": "Klf8", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MDRFINNLEAQLNSESDSMQVYKQVTGPVQTRNRSVTADRSNMTSPLLDASSMENPALFNDIKIEPPEELLASDFNLPQVEPVDLSFHKPKAPLQPASMLQAPIRPPKPPSAAQAIVVSTSSDTGTSATIPTVLTPGSILASSQGTGGQPILHVIHTIPSVGLPNKMGGLKTIPLVVQSLPMVYTSLPADGSPAAITVPLIGGDGKNAGSVKVDPTSMSPLEFPSDSDESAIESGSSALQGLHGLHQEPATMAQMQGEDSLDLKRRRIHQCDFAGCSKVYTKSSHLKAHRRIHTGEKPYKCTWDGCSWKFARSDELTRHFRKHTGIKPFRCTDCNRSFSRSDHLSLHRRRHDTM", "length": 354 }, "evidence": [ { "id": "A0A8V0YJL9", "url": "https://omabrowser.org/oma/group/A0A8V0YJL9/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "O95600-1", "protein_name": "Krueppel-like factor 8", "gene_name": "KLF8", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVDMDKLINNLEVQLNSEGGSMQVFKQVTASVRNRDPPEIEYRSNMTSPTLLDANPMENPALFNDIKIEPPEELLASDFSLPQVEPVDLSFHKPKAPLQPASMLQAPIRPPKPQSSPQTLVVSTSTSDMSTSANIPTVLTPGSVLTSSQSTGSQQILHVIHTIPSVSLPNKMGGLKTIPVVVQSLPMVYTTLPADGGPAAITVPLIGGDGKNAGSVKVDPTSMSPLEIPSDSEESTIESGSSALQSLQGLQQEPAAMAQMQGEESLDLKRRRIHQCDFAGCSKVYTKSSHLKAHRRIHTGEKPYKCTWDGCSWKFARSDELTRHFRKHTGIKPFRCTDCNRSFSRSDHLSLHRRRHDTM", "length": 359 }, "evidence": [ { "id": "A0A8V0YJL9", "url": "https://omabrowser.org/oma/group/A0A8V0YJL9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8BLM0-1", "protein_name": "Krueppel-like factor 8", "gene_name": "Klf8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDKFIDNMDVRIKSESGSMQVFKQVTGPVPTRDPSARADRRNMTSPSFLAASPMENPALFNDIKIEPPEELLESDFNMPQVEPVDLSFHKPKAPLQPASMLQAPIRPPKPPTAPQAIMVPTSADTVTSAAIPTVLTPGSILASSQGTGGQPILHVIHTIPSVSLPNKMSGLKTIPLVVQSLPMVYTSLPTDGSPAAITVPLIGGDGKSAGSVKVDPASMCPLEFPSDSDESAIESGSSALQSLQGFHHEPATMVHMQGEESLDLKRRRIHQCDFAGCSKVYTKSSHLKAHRRIHTGEKPYKCTWDGCSWKFARSDELTRHFRKHTGIKPFRCTDCNRSFSRSDHLSLHRRRHDTM", "length": 355 }, "evidence": [ { "id": "A0A8V0YJL9", "url": "https://omabrowser.org/oma/group/A0A8V0YJL9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJL9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJL9" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJL9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJL9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJL9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJL9" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJL9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJL9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJL9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJL9" } ], "pmid": "" }, { "name": "DNA-binding transcription repressor activity, RNA polymerase II-specific", "id": "GO:0001227", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001227", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJL9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJL9" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJL9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJL9" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJL9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJL9" } ], "pmid": "" }, { "name": "sequence-specific double-stranded DNA binding", "id": "GO:1990837", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990837", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJL9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJL9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 189, "end_pos": 191, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YJL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJL9" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 363, "end_pos": 392, "start_aa": "His", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 189, "end_pos": 191 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YJN8-1", "uniprot_ac": "A0A8V0YJN8", "uniprot_id": "A0A8V0YJN8_CHICK", "mass": { "chemical_mass": 76619.0, "monoisotopic_mass": 76619.0 }, "refseq": { "ac": "XP_040502830", "name": "clathrin interactor 1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040502830" }, "gene_names": [ { "name": "CLINT1", "type": "recommended", "evidence": [ { "id": "A0A8V0YJN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJN8" } ] }, { "name": "CLINT1", "type": "synonym", "evidence": [ { "id": "XP_040502830", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040502830" } ] } ], "protein_names": [ { "name": "Clathrin interactor 1", "type": "synonym", "evidence": [ { "id": "A0A8V0YJN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJN8/entry#names_and_taxonomy" } ] }, { "name": "clathrin interactor 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_040502830", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040502830" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052544.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 1, 2022 this sequence version replaced XP_040502830.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040502830", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040502830" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJN8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJN8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CLINT1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJN8", "locus": { "chromosome": "13", "start_pos": 10885269, "end_pos": 10838228, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012945", "url": "https://www.ensembl.org/id/ENSGALG00010012945" } ] } } ], "crossref": [ { "id": "A0A8V0YJN8", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YJN8", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd16989", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16989", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "416240", "url": "https://www.ncbi.nlm.nih.gov/gene/416240", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR008942", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008942", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013809", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013809", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "AMPTMPH", "url": "https://omabrowser.org/oma/group/AMPTMPH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YJN8", "url": "https://www.orthodb.org/?gene=A0A8V0YJN8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YJP5", "url": "https://www.orthodb.org/?gene=A0A8V0YJP5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12276", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12276", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12276:SF45", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12276:SF45", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01417", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01417", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-432722", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-432722", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_040502830", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040502830", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YJN8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJN8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJN8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJN8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJP5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJP5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJP5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJP5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAGCLPGPAGLLGAFHAPGELCFPFRCPPYLLRSRGRVPLSTCEPSMLACAALGTGKDRTPHCRRRKGTNVVMNYSEIESKVREATNDDPWGPSGQLMGEIAKATFMYEQFPELMNMLWTRMLKDNKKNWRRVYKSLLLLAYLIRNGSERVVTSAREHIYDLRSLENYHFVDENGKDQGINIRQKVKEMVEFAQDDDRLREERKKAKKNKDKYIGVSSDSVGGFRYSERYDPEPKSKWDEDWDKKSTFPFSDKLGELSDKIGSTIDDTISKFRRKDREDSPERCSDSDEEKSRRSKSPKAEFKNEEETVTTKHIHITQATEIITSRHKRSANPSKTIDLGAAAHYTGDKASPEQNAASHAGQPTAKASVSSGSKSSNDLVDLLFDGASQPVATDASADPFGGFADFSSAAASASFPSSQGTTSGNGDFGDWSAFNQASPCPSASSGELFSSTAQQPAIELFSVSQPASGQPPAASNSTDLFDLMGPSQTTMTSSQSMNFSMMSSNAVGIGLPMSRSQPLQSVNTMMPKPNSLYNASTEVVQKSASKTLPSTWSDPSVNISLDNLVPGMQPSKPQQPSLNTMMQQQNMQQPMNVMTQNFAAVNLNPQPNMMPVRPQTSPLMGGSIPVGMGMPSVMPGTMGMTSMGPMPMLNQGTMGMNMNMGVPATGMGLTGAIGMGITNISMTSMTPGTVQPKQDAFANFANFSK", "length": 705, "header": "tr|A0A8V0YJN8-1|A0A8V0YJN8_CHICK Isoform 1 of Clathrin interactor 1 OS=Gallus gallus OX=9031 GN=CLINT1 PE=1 SV=1 CANONICAL=A0A8V0YJN8-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YJN8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJN8/entry#A0A8V0YJN8-1", "sequence": { "sequence": "MAGCLPGPAGLLGAFHAPGELCFPFRCPPYLLRSRGRVPLSTCEPSMLACAALGTGKDRTPHCRRRKGTNVVMNYSEIESKVREATNDDPWGPSGQLMGEIAKATFMYEQFPELMNMLWTRMLKDNKKNWRRVYKSLLLLAYLIRNGSERVVTSAREHIYDLRSLENYHFVDENGKDQGINIRQKVKEMVEFAQDDDRLREERKKAKKNKDKYIGVSSDSVGGFRYSERYDPEPKSKWDEDWDKKSTFPFSDKLGELSDKIGSTIDDTISKFRRKDREDSPERCSDSDEEKSRRSKSPKAEFKNEEETVTTKHIHITQATEIITSRHKRSANPSKTIDLGAAAHYTGDKASPEQNAASHAGQPTAKASVSSGSKSSNDLVDLLFDGASQPVATDASADPFGGFADFSSAAASASFPSSQGTTSGNGDFGDWSAFNQASPCPSASSGELFSSTAQQPAIELFSVSQPASGQPPAASNSTDLFDLMGPSQTTMTSSQSMNFSMMSSNAVGIGLPMSRSQPLQSVNTMMPKPNSLYNASTEVVQKSASKTLPSTWSDPSVNISLDNLVPGMQPSKPQQPSLNTMMQQQNMQQPMNVMTQNFAAVNLNPQPNMMPVRPQTSPLMGGSIPVGMGMPSVMPGTMGMTSMGPMPMLNQGTMGMNMNMGVPATGMGLTGAIGMGITNISMTSMTPGTVQPKQDAFANFANFSK", "length": 705, "header": "tr|A0A8V0YJN8-1|A0A8V0YJN8_CHICK Isoform 1 of Clathrin interactor 1 OS=Gallus gallus OX=9031 GN=CLINT1 PE=1 SV=1 CANONICAL=A0A8V0YJN8-1" }, "locus": { "chromosome": "13", "start_pos": 10883880, "end_pos": 10838697, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031057.1", "url": "https://www.ensembl.org/id/ENSGALT00010031057.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018055.1", "url": "https://www.ensembl.org/id/ENSGALP00010018055.1" } ] } }, { "isoform_ac": "A0A8V0YJP5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJN8/entry#A0A8V0YJP5-1", "sequence": { "sequence": "MNYSEIESKVREATNDDPWGPSGQLMGEIAKATFMYEQFPELMNMLWTRMLKDNKKNWRRVYKSLLLLAYLIRNGSERVVTSAREHIYDLRSLENYHFVDENGKDQGINIRQKVKEMVEFAQDDDRLREERKKAKKNKDKYIGVSSDSVGGFRYSERYDPEPKSKWDEDWDKKSTFPFSDKLGELSDKIGSTIDDTISKFRRKDREDSPERCSDSDEEKSRRSKSPKAEFKNEEETVTTKHIHITQATEIITSRHKRSANPSKTIDLGAAAHYTGDKASPEQNAASHAGQPTAKASVSSGSKSSNDLVDLLFDGASQPVATDASADPFGGFADFSSAAASASFPSSQGTTSGNGDFGDWSAFNQASPCPSASSGELFSSTAQQPAIELFSVSQPASGQPPAASNSTDLFDLMGPSQTTMTSSQSMNFSMMSSNAVGIGLPMSRSQPLQSVNTMMPKPNSLYNASTEVVQKSASKTLPSTWSDPSVNISLDNLVPGMQPSKPQQPSLNTMMQQQNMQQPMNVMTQNFAAVNLNPQPNMMPVRPQTSPLMGGSIPVGMGMPSVMPGTMGMTSMGPMPMLNQGTMGMNMNMGVPATGMGLTGAIGMGITNISMTSMTPGTVQPKQDAFANFANFSK", "length": 633, "header": "tr|A0A8V0YJP5-1|A0A8V0YJP5_CHICK Computationally mapped isoform of Clathrin interactor 1 OS=Gallus gallus OX=9031 GN=CLINT1 PE=1 SV=1 CANONICAL=A0A8V0YJN8-1" }, "locus": { "chromosome": "13", "start_pos": 10883880, "end_pos": 10861327, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031064.1", "url": "https://www.ensembl.org/id/ENSGALT00010031064.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018060.1", "url": "https://www.ensembl.org/id/ENSGALP00010018060.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-432722", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-432722", "resource": "Reactome", "description": "Golgi Associated Vesicle Biogenesis" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "clathrin vesicle coat", "id": "GO:0030125", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030125", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJN8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJN8" } ], "pmid": "" }, { "name": "endosome", "id": "GO:0005768", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005768", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJN8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJN8" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJN8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJN8" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJN8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJN8" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJN8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJN8" } ], "pmid": "" }, { "name": "endomembrane system", "id": "GO:0012505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0012505", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJN8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJN8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "phospholipid binding", "id": "GO:0005543", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005543", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJN8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJN8" } ], "pmid": "" }, { "name": "clathrin binding", "id": "GO:0030276", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030276", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJN8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJN8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "endocytosis", "id": "GO:0006897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006897", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJN8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJN8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 146, "end_pos": 148, "annotation": "n_glycosylation_sequon" }, { "start_pos": 476, "end_pos": 478, "annotation": "n_glycosylation_sequon" }, { "start_pos": 498, "end_pos": 500, "annotation": "n_glycosylation_sequon" }, { "start_pos": 534, "end_pos": 536, "annotation": "n_glycosylation_sequon" }, { "start_pos": 558, "end_pos": 560, "annotation": "n_glycosylation_sequon" }, { "start_pos": 679, "end_pos": 681, "annotation": "n_glycosylation_sequon" }, { "start_pos": 702, "end_pos": 704, "annotation": "n_glycosylation_sequon" }, { "start_pos": 74, "end_pos": 76, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YJN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJN8" }, { "id": "PS50942", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50942" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "ENTH", "eco_id": "ECO_0000259", "start_pos": 70, "end_pos": 203, "start_aa": "Asn", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 146, "end_pos": 148 }, { "start_pos": 476, "end_pos": 478 }, { "start_pos": 498, "end_pos": 500 }, { "start_pos": 534, "end_pos": 536 }, { "start_pos": 558, "end_pos": 560 }, { "start_pos": 679, "end_pos": 681 }, { "start_pos": 702, "end_pos": 704 }, { "start_pos": 74, "end_pos": 76 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YJP0-1", "uniprot_ac": "A0A8V0YJP0", "uniprot_id": "A0A8V0YJP0_CHICK", "mass": { "chemical_mass": 34886.0, "monoisotopic_mass": 34886.0 }, "refseq": { "ac": "NP_001025788", "name": "hepatitis A virus cellular receptor 2 isoform 3 precursor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025788" }, "gene_names": [ { "name": "HAVCR1", "type": "recommended", "evidence": [ { "id": "A0A8V0YJP0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJP0" } ] }, { "name": "HAVCR1", "type": "synonym", "evidence": [ { "id": "NP_001025788", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025788" } ] }, { "name": "HAVCR", "type": "synonym", "evidence": [ { "id": "NP_001025788", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025788" } ] } ], "protein_names": [ { "name": "Hepatitis A virus cellular receptor 1", "type": "synonym", "evidence": [ { "id": "A0A8V0YJP0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJP0/entry#names_and_taxonomy" } ] }, { "name": "hepatitis A virus cellular receptor 1", "type": "synonym", "evidence": [ { "id": "NP_001025788", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025788" } ] }, { "name": "hepatitis A virus cellular receptor 2 isoform 3 precursor", "type": "synonym", "evidence": [ { "id": "NP_001025788", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025788" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: ERR2365565.68234.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000256.1. On Sep 23, 2021 this sequence version replaced NP_001025788.2. Transcript Variant: This variant (3) lacks an exon in the 3' coding region, compared to variant 1, which results in a frameshift and an isoform (3) with a longer and distinct C-terminus, compared to isoform 1.", "evidence": [ { "database": "RefSeq", "id": "NP_001025788", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025788" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJP0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJP0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "HAVCR1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJP0", "locus": { "chromosome": "13", "start_pos": 11071522, "end_pos": 11060703, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010015098", "url": "https://www.ensembl.org/id/ENSGALG00010015098" } ] } } ], "crossref": [ { "id": "A0A8V0YJP0", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YJP0", "database": "AlphaFoldDB", "categories": [] }, { "id": "416249", "url": "https://www.ncbi.nlm.nih.gov/gene/416249", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013106", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013106", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:416249", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416249", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WCNNILA", "url": "https://omabrowser.org/oma/group/WCNNILA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YJP0", "url": "https://www.orthodb.org/?gene=A0A8V0YJP0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YR26", "url": "https://www.orthodb.org/?gene=A0A8V0YR26", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YR76", "url": "https://www.orthodb.org/?gene=A0A8V0YR76", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46608", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46608", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46608:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46608:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07686", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07686", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001025788", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025788", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YJP0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJP0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJP0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJP0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YR26", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YR26", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YR26-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YR26-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YR76", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YR76", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YR76-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YR76-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSSHFFLDWILLIWLTGPTVSGLLVKGEVGQNVTVPCFYRVKTEYDITSMCWGRDACPASKCSQPIIWTDGRKVTERHHTKYVLKGDLLKGNVSLTILNAQETDSGTYCCRVEIPGWFNDETTNLQVVVERARVSTASPLTHTSPPTSAPGSASEESFTVSTWPPVSVSEAPETASGSYSSTSDYPEVTSSLQNSSISTHSQQYSEKTVYLRTGLCVAFLVILVVGLFLGRPLLHFGEQNVLGTKVPWKLRSTQRKTFTQYTKDCMRAHLCHLWDFKYFPKMIAAPSALQLSVSGLLKHHSYHSSKANKSYNSN", "length": 314, "header": "tr|A0A8V0YJP0-1|A0A8V0YJP0_CHICK Isoform 1 of Hepatitis A virus cellular receptor 1 OS=Gallus gallus OX=9031 GN=HAVCR1 PE=3 SV=1 CANONICAL=A0A8V0YJP0-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YJP0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJP0/entry#A0A8V0YJP0-1", "sequence": { "sequence": "MSSHFFLDWILLIWLTGPTVSGLLVKGEVGQNVTVPCFYRVKTEYDITSMCWGRDACPASKCSQPIIWTDGRKVTERHHTKYVLKGDLLKGNVSLTILNAQETDSGTYCCRVEIPGWFNDETTNLQVVVERARVSTASPLTHTSPPTSAPGSASEESFTVSTWPPVSVSEAPETASGSYSSTSDYPEVTSSLQNSSISTHSQQYSEKTVYLRTGLCVAFLVILVVGLFLGRPLLHFGEQNVLGTKVPWKLRSTQRKTFTQYTKDCMRAHLCHLWDFKYFPKMIAAPSALQLSVSGLLKHHSYHSSKANKSYNSN", "length": 314, "header": "tr|A0A8V0YJP0-1|A0A8V0YJP0_CHICK Isoform 1 of Hepatitis A virus cellular receptor 1 OS=Gallus gallus OX=9031 GN=HAVCR1 PE=3 SV=1 CANONICAL=A0A8V0YJP0-1" }, "locus": { "chromosome": "13", "start_pos": 11069017, "end_pos": 11062685, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010036361.1", "url": "https://www.ensembl.org/id/ENSGALT00010036361.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021150.1", "url": "https://www.ensembl.org/id/ENSGALP00010021150.1" } ] } }, { "isoform_ac": "A0A8V0YR26-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJP0/entry#A0A8V0YR26-1", "sequence": { "sequence": "MSSHFFLDWILLIWLTGPTVSGLLVKGEVGQNVTVPCFYRVKTEYDITSMCWGRDACPASKCSQPIIWTDGRKVTERHHTKYVLKGDLLKGNVSLTILNAQETDSGTYCCRVEIPGWFNDETTNLQVVVERAPGSASEESFTVSTWPPVSVSEAPETASGSYSSTSDYPEVTSSLQNSSISTHSQQYSEKTVYLRTGLCVAFLVILVVGLFLGRRKYFSEVVIQVWVG", "length": 228, "header": "tr|A0A8V0YR26-1|A0A8V0YR26_CHICK Computationally mapped isoform of Hepatitis A virus cellular receptor 1 OS=Gallus gallus OX=9031 GN=HAVCR1 PE=3 SV=1 CANONICAL=A0A8V0YJP0-1" }, "locus": { "chromosome": "13", "start_pos": 11067889, "end_pos": 11062685, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010036357.1", "url": "https://www.ensembl.org/id/ENSGALT00010036357.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021147.1", "url": "https://www.ensembl.org/id/ENSGALP00010021147.1" } ] } }, { "isoform_ac": "A0A8V0YR76-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJP0/entry#A0A8V0YR76-1", "sequence": { "sequence": "MAVLPELFFSQNGPTVSGLLVKGEVGQNVTVPCFYRVKTEYDITSMCWGRDACPASKCSQPIIWTDGRKVTERHHTKYVLKGDLLKGNVSLTILNAQETDSGTYCCRVEIPGWFNDETTNLQVVVERARVSTASPLTHTSPPTSAPGSASEESFTVSTWPPVSVSEAPETASGSYSSTSDYPEVTSSLQNSSISTHSQQYSEKTVYLRTGLCVAFLVILVVGLFLGRRYLRNMKKLSKFASSVAFWRTERAGNQSALEVEIHAEENIYTIH", "length": 271, "header": "tr|A0A8V0YR76-1|A0A8V0YR76_CHICK Computationally mapped isoform of Hepatitis A virus cellular receptor 1 OS=Gallus gallus OX=9031 GN=HAVCR1 PE=3 SV=1 CANONICAL=A0A8V0YJP0-1" }, "locus": { "chromosome": "13", "start_pos": 11068860, "end_pos": 11060902, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010036373.1", "url": "https://www.ensembl.org/id/ENSGALT00010036373.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021160.1", "url": "https://www.ensembl.org/id/ENSGALP00010021160.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 19, "start_aa": "Thr", "end_pos": 19, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr19", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:416249", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416249", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJP0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJP0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "phosphatidylserine binding", "id": "GO:0001786", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001786", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJP0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJP0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "apoptotic cell clearance", "id": "GO:0043277", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043277", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJP0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJP0" } ], "pmid": "" }, { "name": "cytoskeletal rearrangement involved in phagocytosis, engulfment", "id": "GO:0060097", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060097", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJP0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJP0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 194, "end_pos": 196, "annotation": "n_glycosylation_sequon" }, { "start_pos": 308, "end_pos": 310, "annotation": "n_glycosylation_sequon" }, { "start_pos": 32, "end_pos": 34, "annotation": "n_glycosylation_sequon" }, { "start_pos": 92, "end_pos": 94, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YJP0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJP0" }, { "id": "PS50835", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50835" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ig-like", "eco_id": "ECO_0000259", "start_pos": 18, "end_pos": 130, "start_aa": "Pro", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 19 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 194, "end_pos": 196 }, { "start_pos": 308, "end_pos": 310 }, { "start_pos": 32, "end_pos": 34 }, { "start_pos": 92, "end_pos": 94 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": 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"uniprot_ac": "A0A8V0YJQ7", "uniprot_id": "A0A8V0YJQ7_CHICK", "mass": { "chemical_mass": 229027.0, "monoisotopic_mass": 229027.0 }, "refseq": { "ac": "XP_004949130", "name": "uncharacterized protein KIAA2026 homolog isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004949130" }, "gene_names": [ { "name": "KIAA2026", "type": "recommended", "evidence": [ { "id": "A0A8V0YJQ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJQ7" } ] }, { "name": "KIAA2026", "type": "synonym", "evidence": [ { "id": "XP_004949130", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004949130" } ] } ], "protein_names": [ { "name": "Bromodomain containing 10", "type": "synonym", "evidence": [ { "id": "A0A8V0YJQ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJQ7/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein KIAA2026 homolog isoform X1", "type": "synonym", "evidence": [ { "id": "XP_004949130", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004949130" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052572.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_004949130.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004949130", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004949130" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJQ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJQ7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "KIAA2026", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJQ7", "locus": {} } ], "crossref": [ { "id": "cd04369", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04369", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "427227", "url": "https://www.ncbi.nlm.nih.gov/gene/427227", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR036427", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036427", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040214", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040214", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056522", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056522", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:427227", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427227", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DAQENAY", "url": "https://omabrowser.org/oma/group/DAQENAY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YJQ1", "url": "https://www.orthodb.org/?gene=A0A8V0YJQ1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YJQ7", "url": "https://www.orthodb.org/?gene=A0A8V0YJQ7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31095", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31095", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31095:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31095:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF23450", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23450", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_004949130", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004949130", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YJQ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJQ1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJQ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJQ1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJQ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJQ7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJQ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJQ7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLRSRPAAGGAPAAAEALCARGAADMDSARPADVAEQTAGHAAGGDLSVERASACPPQRREEQRDEDGSDAGGESGGCSWEQSLSPELQQGYRILREFLLEKYRPLTAPFLKPLADQECVRAEGGAGSLSGHNSSHSAQQSPAGMWLLKMEEKFSSGQYAGIADFVGDFRQMLETCYRLHGVDHWLSKQAQKLEMMLEQKLALLSRHLREKTSLAVTSRGSYGLEDEKGTPCTSTRRRSTPRNLVGLSTGMFESVMVQVLRQEEQLRAKEEKRMREQERKEAEEASQKEIEEWEKSLLAQAAPTRMETMWEIPAIGHFLCLAQQILNLPEIVFYELERCLLMPQCNAFLSKIMTSLLSPPHRRSTLHRRPTLSYRAWEAALRQKVQHWYNVVGQTDNPNSSAEKLGLCPQFFKVLGEVNPLQEKPFHELPFYQKVWLLKGLCDFVYETQKDVQDAVLGQPIHECREVILGYDYLENAYVHFPQFCGADVRIYKQKPFQAPEFPSPPIKVKKVPRTKIEKVKYEYVSKSNGAVSSGGRGDLLPRSKSEVGKSMGSIAGCPEKDTHLDSFSVTTEIKINCEMKTSGVCDIKKAGCYKENLRHLISSGEIVSMADRFSSGERRPAENGQGCAEMARVKVEISPFKENTLKACQMLVNGTHNDNQDTDYNRSAKEIMLENSLRSNNNKLIKLRAKKKKKKKKKLKDILNENLQKKLDDLQRRREVHLYPFKSYKSEIQSKLFKKKAKHKKHKSGKKSVSKKAITKKRKGVTKSAIPEFQLICTNLDELRELITKIENELKDLEDIKKKSGRWYHRKQAVKELHGTLIRLLNELLPWEPKLMKAFQRNRSRLKKDYDEFKRHPDHDKFTRELWSNDESEVDAGKDCFAIVSSKSSESAEYVEIPRKDHPDNDEMKLLEMNLPAGKSKLLKKESTSKEIHKTLLKSFKRQSKQNSCLDQNTNELSPRKKAKLSTSEAAVQSSESSLQTDSCLTDLKQLEGSSPESFSLTDPATSVSSFLKGTKPIQALLAKNIGNKVTLTNQLSPPPGINVSTSEKPVLSPVESSLIKPALPCQTGSKTPLQMVYKMPNGHCVPVDLHNSSVKIQMQPVIDPKTGEKVMQQVLILPKNFLLQQKEGKVMSKDSNLLQQNSSELHCATFPEITNVTVSLTPVLVTAPANVTSHSTSTIFNKNICNLSQGTVSTNSTQTLPTTTSSLVSSTVKVCQTEHDKLRTEVSTTTFPVFLSSPSISTASQSLISATALSASTNTATAFHCLASQQATESFETRQELKTVCIRESQSILVTTRGGNTGIVKVQTNPDQISPTSISSGSVLTYASQFKAFLVPKTTALSSSTLPSVATATSSLPHFGQSSVSGFAPSTGSSFNTPPFPADFNQAVDKSIKFTLQQPATGSSLGQVVENTCQVSCPSSSCISSASSSISATPNSPISVTSTSQNNTVVTPNSSVQQQCDTKTKTNSVIQSESSSVINGDFISGTPVQKLTLVTNPPILSPCGASGVSVIPSLAPTGVSAQKLVFINTPIPNGPSATTLVAESLKHNLPSSISKTFVSATEQPQLVLIPSTMGAPIRINSSPTIAQVKDVKIGLNIGQTIVNTKGSAQQTPPVNILHSAVSKGEDKKNIGLALSLTSTNSLVPVCSSFISQSAVSINESLCVAAKATNSFSVPTANACPESVSVAPSGTSGTRPTVLSGGNDPSKVRPVLGSRLCTANIGNTVGISTVKTGHLASSVLISTTQPMVSSQNLTSALQFPVISLSGSVATPRKVLHTVPQLAAVPAPPPVPKSQLPTLLQFQSSGVTAAGPSNAGTQKPQSLLTPASPNTGKVVSFPSFSSLQCKQVPPSLEKQSPAYSVASTIQMCVASPAITSKTGGQLNEPCIQQKIVINTCMPLAPGTQIMINGTCFVVPPQGLGAGSHVLLLSYNTKQTPPLNINHGQEAQGVPVVNPITSKIILAPSNSLSWQTSQRLLKNSTKIVNSFGSADALPIVHATPQILSTPSSSCTPLPAATLSVSSVIKSPAYVPTTSSVVSAVHPSNSHLPSNTSVFQLDTSIKKLLVSPEGAILNAINTPASKVSSLSSSLPPVVVSTSRISTTVFPISQSSCLDKPDNAAS", "length": 2119, "header": "tr|A0A8V0YJQ7-1|A0A8V0YJQ7_CHICK Isoform 1 of Bromodomain containing 10 OS=Gallus gallus OX=9031 GN=KIAA2026 PE=4 SV=1 CANONICAL=A0A8V0YJQ7-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YJQ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJQ7/entry#A0A8V0YJQ1-1", "sequence": { "sequence": "MLRSRPAAGGAPAAAEALCARGAADMDSARPADVAEQTAGHAAGGDLSVERASACPPQRREEQRDEDGSDAGGESGGCSWEQSLSPELQQGYRILREFLLEKYRPLTAPFLKPLADQECVRAEGGAGSLSGHNSSHSAQQSPAGMWLLKMEEKFSSGQYAGIADFVGDFRQMLETCYRLHGVDHWLSKQAQKLEMMLEQKLALLSRHLREKTSLAVTSRGSYGLEDEKGTPCTSTRRRSTPRNLVGLSTGMFESVMVQVLRQEEQLRAKEEKRMREQERKEAEEASQKEIEEWEKSLLAQAAPTRMETMWEIPAIGHFLCLAQQILNLPEIVFYELERCLLMPQCNAFLSKIMTSLLSPPHRRSTLHRRPTLSYRAWEAALRQKVQHWYNVVGQTDNPNSSAEKLGLCPQFFKVLGEVNPLQEKPFHELPFYQKVWLLKGLCDFVYETQKDVQDAVLGQPIHECREVILGYDYLENAYVHFPQFCGADVRIYKQKPFQAPEFPSPPIKVKKVPRTKIEKVKYEYVSKSNGAVSSGGRGDLLPRSKSEVGKSMGSIAGCPEKDTHLDSFSVTTEIKINCEMKTSGVCDIKKAGCYKENLRHLISSGEIVSMADRFSSGERRPAENGQGCAEMARVKVEISPFKENTLKACQMLVNGTHNDNQDTDYNRSAKEIMLENSLRSNNNKLIKLRAKKKKKKKKKLKDILNENLQKKLDDLQRRREVHLYPFKSYKSEIQSKLFKKKAKHKKHKSGKKSVSKKAITKKRKGVTKSAIPEFQGRWYHRKQAVKELHGTLIRLLNELLPWEPKLMKAFQRNRSRLKKDYDEFKRHPDHDKFTRELWSNDESEVDAGKDCFAIVSSKSSESAEYVEIPRKDHPDNDEMKLLEMNLPAGKSKLLKKESTSKEIHKTLLKSFKRQSKQNSCLDQNTNELSPRKKAKLSTSEAAVQSSESSLQTDSCLTDLKQLEGSSPESFSLTDPATSVSSFLKGTKPIQALLAKNIGNKVTLTNQLSPPPGINVSTSEKPVLSPVESSLIKPALPCQTGSKTPLQMVYKMPNGHCVPVDLHNSSVKIQMQPVIDPKTGEKVMQQVLILPKNFLLQQKEGKVMSKDSNLLQQNSSELHCATFPEITNVTVSLTPVLVTAPANVTSHSTSTIFNKNICNLSQGTVSTNSTQTLPTTTSSLVSSTVKVCQTEHDKLRTEVSTTTFPVFLSSPSISTASQSLISATALSASTNTATAFHCLASQQATESFETRQELKTVCIRESQSILVTTRGGNTGIVKVQTNPDQISPTSISSGSVLTYASQFKAFLVPKTTALSSSTLPSVATATSSLPHFGQSSVSGFAPSTGSSFNTPPFPADFNQAVDKSIKFTLQQPATGSSLGQVVENTCQVSCPSSSCISSASSSISATPNSPISVTSTSQNNTVVTPNSSVQQQCDTKTKTNSVIQSESSSVINGDFISGTPVQKLTLVTNPPILSPCGASGVSVIPSLAPTGVSAQKLVFINTPIPNGPSATTLVAESLKHNLPSSISKTFVSATEQPQLVLIPSTMGAPIRINSSPTIAQVKDVKIGLNIGQTIVNTKGSAQQTPPVNILHSAVSKGEDKKNIGLALSLTSTNSLVPVCSSFISQSAVSINESLCVAAKATNSFSVPTANACPESVSVAPSGTSGTRPTVLSGGNDPSKVRPVLGSRLCTANIGNTVGISTVKTGHLASSVLISTTQPMVSSQNLTSALQFPVISLSGSVATPRKVLHTVPQLAAVPAPPPVPKSQLPTLLQFQSSGVTAAGPSNAGTQKPQSLLTPASPNTGKVVSFPSFSSLQCKQVPPSLEKQSPAYSVASTIQMCVASPAITSKTGGQLNEPCIQQKIVINTCMPLAPGTQIMINGTCFVVPPQGLGAGSHVLLLSYNTKQTPPLNINHGQEAQGVPVVNPITSKIILAPSNSLSWQTSQRLLKNSTKIVNSFGSADALPIVHATPQILSTPSSSCTPLPAATLSVSSVIKSPAYVPTTSSVVSAVHPSNSHLPSNTSVFQLDTSIKKLLVSPEGAILNAINTPASKVSSLSSSLPPVVVSTSRISTTVFPISQSSCLDKPDNAAS", "length": 2089, "header": "tr|A0A8V0YJQ1-1|A0A8V0YJQ7_CHICK Computationally mapped isoform of Bromodomain containing 10 OS=Gallus gallus OX=9031 GN=KIAA2026 PE=4 SV=1 CANONICAL=A0A8V0YJQ7-1" }, "locus": { "chromosome": "Z", "start_pos": 28301941, "end_pos": 28240039, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031070.1", "url": "https://www.ensembl.org/id/ENSGALT00010031070.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018065.1", "url": "https://www.ensembl.org/id/ENSGALP00010018065.1" } ] } }, { "isoform_ac": "A0A8V0YJQ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJQ7/entry#A0A8V0YJQ7-1", "sequence": { "sequence": "MLRSRPAAGGAPAAAEALCARGAADMDSARPADVAEQTAGHAAGGDLSVERASACPPQRREEQRDEDGSDAGGESGGCSWEQSLSPELQQGYRILREFLLEKYRPLTAPFLKPLADQECVRAEGGAGSLSGHNSSHSAQQSPAGMWLLKMEEKFSSGQYAGIADFVGDFRQMLETCYRLHGVDHWLSKQAQKLEMMLEQKLALLSRHLREKTSLAVTSRGSYGLEDEKGTPCTSTRRRSTPRNLVGLSTGMFESVMVQVLRQEEQLRAKEEKRMREQERKEAEEASQKEIEEWEKSLLAQAAPTRMETMWEIPAIGHFLCLAQQILNLPEIVFYELERCLLMPQCNAFLSKIMTSLLSPPHRRSTLHRRPTLSYRAWEAALRQKVQHWYNVVGQTDNPNSSAEKLGLCPQFFKVLGEVNPLQEKPFHELPFYQKVWLLKGLCDFVYETQKDVQDAVLGQPIHECREVILGYDYLENAYVHFPQFCGADVRIYKQKPFQAPEFPSPPIKVKKVPRTKIEKVKYEYVSKSNGAVSSGGRGDLLPRSKSEVGKSMGSIAGCPEKDTHLDSFSVTTEIKINCEMKTSGVCDIKKAGCYKENLRHLISSGEIVSMADRFSSGERRPAENGQGCAEMARVKVEISPFKENTLKACQMLVNGTHNDNQDTDYNRSAKEIMLENSLRSNNNKLIKLRAKKKKKKKKKLKDILNENLQKKLDDLQRRREVHLYPFKSYKSEIQSKLFKKKAKHKKHKSGKKSVSKKAITKKRKGVTKSAIPEFQLICTNLDELRELITKIENELKDLEDIKKKSGRWYHRKQAVKELHGTLIRLLNELLPWEPKLMKAFQRNRSRLKKDYDEFKRHPDHDKFTRELWSNDESEVDAGKDCFAIVSSKSSESAEYVEIPRKDHPDNDEMKLLEMNLPAGKSKLLKKESTSKEIHKTLLKSFKRQSKQNSCLDQNTNELSPRKKAKLSTSEAAVQSSESSLQTDSCLTDLKQLEGSSPESFSLTDPATSVSSFLKGTKPIQALLAKNIGNKVTLTNQLSPPPGINVSTSEKPVLSPVESSLIKPALPCQTGSKTPLQMVYKMPNGHCVPVDLHNSSVKIQMQPVIDPKTGEKVMQQVLILPKNFLLQQKEGKVMSKDSNLLQQNSSELHCATFPEITNVTVSLTPVLVTAPANVTSHSTSTIFNKNICNLSQGTVSTNSTQTLPTTTSSLVSSTVKVCQTEHDKLRTEVSTTTFPVFLSSPSISTASQSLISATALSASTNTATAFHCLASQQATESFETRQELKTVCIRESQSILVTTRGGNTGIVKVQTNPDQISPTSISSGSVLTYASQFKAFLVPKTTALSSSTLPSVATATSSLPHFGQSSVSGFAPSTGSSFNTPPFPADFNQAVDKSIKFTLQQPATGSSLGQVVENTCQVSCPSSSCISSASSSISATPNSPISVTSTSQNNTVVTPNSSVQQQCDTKTKTNSVIQSESSSVINGDFISGTPVQKLTLVTNPPILSPCGASGVSVIPSLAPTGVSAQKLVFINTPIPNGPSATTLVAESLKHNLPSSISKTFVSATEQPQLVLIPSTMGAPIRINSSPTIAQVKDVKIGLNIGQTIVNTKGSAQQTPPVNILHSAVSKGEDKKNIGLALSLTSTNSLVPVCSSFISQSAVSINESLCVAAKATNSFSVPTANACPESVSVAPSGTSGTRPTVLSGGNDPSKVRPVLGSRLCTANIGNTVGISTVKTGHLASSVLISTTQPMVSSQNLTSALQFPVISLSGSVATPRKVLHTVPQLAAVPAPPPVPKSQLPTLLQFQSSGVTAAGPSNAGTQKPQSLLTPASPNTGKVVSFPSFSSLQCKQVPPSLEKQSPAYSVASTIQMCVASPAITSKTGGQLNEPCIQQKIVINTCMPLAPGTQIMINGTCFVVPPQGLGAGSHVLLLSYNTKQTPPLNINHGQEAQGVPVVNPITSKIILAPSNSLSWQTSQRLLKNSTKIVNSFGSADALPIVHATPQILSTPSSSCTPLPAATLSVSSVIKSPAYVPTTSSVVSAVHPSNSHLPSNTSVFQLDTSIKKLLVSPEGAILNAINTPASKVSSLSSSLPPVVVSTSRISTTVFPISQSSCLDKPDNAAS", "length": 2119, "header": "tr|A0A8V0YJQ7-1|A0A8V0YJQ7_CHICK Isoform 1 of Bromodomain containing 10 OS=Gallus gallus OX=9031 GN=KIAA2026 PE=4 SV=1 CANONICAL=A0A8V0YJQ7-1" }, "locus": { "chromosome": "Z", "start_pos": 28301941, "end_pos": 28240039, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031075.1", "url": "https://www.ensembl.org/id/ENSGALT00010031075.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018070.1", "url": "https://www.ensembl.org/id/ENSGALP00010018070.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:427227", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427227", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "F1LRC7-1", "protein_name": "Bromodomain containing 10", "gene_name": "Brd10", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSVPETPGEMERAAEEERPPPPTGEGNEEEVVAAAARASGLVRRRSASSVDDEEEEAAAETTVVAGGGCKEQELTYELQQGYRILGEFLQEKHRGLTAPFLQPLGGVAAGEEEVAEGRRSGGRGSRVPPQQPGQGMCLLKMEEKFSSGQYRGITEFVADFRLMLETCYRLHGVDHWISKQGQKLEMLLEQKLALLSRHLREKTTIAVTSRGYYGLEEEKGTACTSTRRRSTPRSLAGLTSGVFESIMVQVLRQEEQLRAKEEKRLREQERKEAEEACQKEVEEWERKLLAQAAPACMENMWEIPAIGHFLCLAQQILNLPEIVFYELERCLLMPQCNAFLSKIMTSLLSPPHRRPTLHRRPTLPYRTWEAVLRQKVRQWYTAVGQTENPGNCAEKLGLCPQFFKVLGEVNPLEERPFHELPFYQKVWLLKGLCDFVYETQKEVQDAVLGQPIHECREVILGYDYLENAYVHFPQFCGADVRIYKQRPFQAPEFPVPPIKVKRVPRIKLEKFKCDYVNTSNGEHRCNREGLPLTFKKEQEIDFDPAYCPAKMNFDNHDITVEVEVKANCDIKVHRPCEIEKTDCCKENLQKPRSPGEVTGFGEPLSPGEIRFIENQEKYGEASKIKTESNPLKENALKSCQIHINGSHIDHPDINCRKAVRDILLEHSLQSHKKLKLTKMRAKKKKKKKKKLKDVLSENLQRKREGLHSLPFKSYKPEIQSKLLIIKKKGKHKKHKSGKKSISKKAITKKRKTVTKSPAVPEFQLICTNLDELRELITKIENELKDLENSRKKSGRWYHRRQAVKELHSTLIRLLNELLPWEPKLMKAFQRNRSRLKKDYDDFRRQPDHGQFTRELWTTEESEGHPEREAPKAELSKSVDAAEPLDSLDKEREDSDDMKLSDIGFPMARSKLLKKELPSKDTVKTLPKALKRQSKQSSCPDDSAEELSPRKRARLSTSEPSAENLDVEMPIDCLSECKPAELPFQESFASKDSVPVSTLQKGTKPIQALLAKNIGNKVTLTNQLPPSTGRSVPAVEKPAPSPAETSPIKPALTCLTSTKGPLQMVYKIPCGQWLPVDLHSSSVKIQMQPVVDSKTGEKIMQQVLILPKNFVIQHKEGKAVAKEIAAPQQKGAEHCSPCPQTTSVNCSLVSVPVTSVCTQLPDTVLNKTVTLSSNVSARSQPLSPVTSVSNVLISPVKTSQSEAGKVKSTVSSNTFPQSNTSPTISSTVQPLLPATTLNEFTDPGSSLPCFSQQTVDSSEAKQELKTVCIRDSQSILVRTRGGNTGVVKVQTNPEQNSPNSLSSSSVFTFAPQFQAFLVPKSTSCPTSSQVAGVTATSSLPSFSQAPTSMSITCGSHPPVGKNLKSTVGQTFSSGYAGPMIEKMPCMPSSPLKPSISSSSLLPPPTNSSVSVISISAGNFGQSNASVIHTSTKPQQVDCITKSYPVTGSEATTAINGDVLSVVSAPPLPPPGSAPSAAVAPAPASAGASTQKVVFINAPAPSGTSSSALVAESLKQTLPSPLSKTYVKNPEQPQIVLIPSTVGAPRKVNSSPAVSQIKDVKIGLNIGQAIINPPGNLPAVSSINILQSVMPKAEDKSNKGCISPISPSSNSVPASSNIVSQTLPPASESARAANTFSGIAANVPLSSLSVTSSPASVGTRPPVLVSGNDTSSRIMPVLSNRLCTSNLGNTVAISTVKTGHLASSVLISTTQPAVSPRCLTSALQIPVTVALPPPVTTSPKIINTAPQSAAVPGATHPVSLPKKQSRTSLQFQSPGTTATVPTNANTTKPPAEFSSPSPSPGKIVSISNVPSVPNQHVPPSLVKTTLSNNSLAGGSAIHTCSPPSNITGLAGAPFTEPCIQQKIVINTSTPLAPGTQIMMNGARFIVPPQGLGAGSHVLLIATNPKYGPPLLLNSGQSILATPVDNPVQKIIQTSNSSLSGQPLKHSVRNSTKIVNSFGSPSSLSAVHTAPHIVNTPAKACVPPAPPAPLTSVIKASPAALLAKTSLVSAVSPSNPPLPSSTSVFHLDTSVKKLLVSPEGAILNTINTPAAKAPSLSSSLPPVVTASQNPAPVFPAFPSSGLEKPDTAAS", "length": 2087 }, "evidence": [ { "id": "A0A8V0YJQ7", "url": "https://omabrowser.org/oma/group/A0A8V0YJQ7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3MZW1-1", "protein_name": "Bromodomain containing 10", "gene_name": "BRD10", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSVPGKPGEMKPAGEEERPPPAAEEEDDDELVAAAPALRPARRSASLREDADDDEEEEEMVVGGGGCKEQELTYELQQGYRILGEFLQEKHRGLTAPFLQPLGGVATREEEAAEGPRGGGRGSRALPQQPGQGMCLLKMEEKFASGQYGGITEFVADFRLMLETCYRQHGVDHWISKQGQKLEMMLEQKLALLSRLREQERKEAEEASQKEIEEWERKLLAQAAPTCMETMWEIPAIGHFLCLAQQILNLPEIVFYELERCLLMPQCNAFLSKIMTSLLSPPHRRPTLHRRPTLPYRTWEAALRQKVQQWYTAVGQTENPDNCAEKLGLCPQFFKVLGEVNPLEEKPFHELPFYQKVWILKGLCDFVYETQKEVQDAVLGQPIHECREVILGYDYLENAYVHFPQFCGADVRIYKQRPFQAPEFPIPPIKIQRVPRIKLEKLKCDYVSASNGEHRCSREGLPSAFRKEQEINFDPTCCPAKMNLDNHDISVETEVNSNCEIRIRRPCEMNITDCCKENLEKPGSPGEVTSFGEPLSPGEIRFIENQEKYGEASRVKPEPSPLKENALKSCQIHVNGSHSDHPDINCHKVVRDILLEQSLQSHKKLKLTKMRAKKKKKKKKKLKDILNENLQRKRESLHSLAFKSYKPEIQNKLLIIKKKAKHKKHKSGKKSISKKAITKKRKTVTKSPTVPEFQLICTNLDELRELITKIENELKDLENNRKKSGKWYHRRQAVKELHSTLIRLLNELLPWEPKLMKAFQRNRSRLKKDYDDFRRQPDHDKFARELWTSEEGEGDPGRETPKVEISSKSVDTTEPLDILEKDHFDLDDMKLSEIDFPMARSKLLKKELPSKDVLKTLPKTLKRQSKQISYLDDSTKELSPRKKAKLSTNETVVENAEGDVQMDCLNESKHTEPLCPESFASLDSTPVSTLQKGTKPIQALLAKNIGNKVTLTNQLPPSTGRSAPAVEKPVISPPEASPIKPALTCHTSTKGPLQMVYKMPCGQWLPLDLHNSSVKIQMQPMLDPKSGEKIMQQVLILPKNFVIQHKEGKAVAKEIPPLQQKGTEQHGSSFPQTANVNSSLPSVLVNPTGTVSTQLPNTAFNKTVTPLSNVSSARPQSLTSVTSISNLLAPPVKTSQSEAGKFKNTVSATAFPQPIASPTISSTVQPQLSATTLNGSTNSSSSLNCFAQQTADSSEAKQELKTVCIRDSQSILVRTRGGNTGVVKVQTNPDQNSPNSLSSSSVFTIAPQLQAFLVPKSTASSSSAFSSVAGTTATSSLPSFGQALTSVSIPAGFNPSTGKNLKFTLSQPSCSGNLGHMIDKTSPMPSSPLKSSVSSSPLLSTANSSVSVINVSTGNCGQTSSNVIRTPAKHQQVDYVTKSYPVTRSEATANGDTISGTPVQKLMLVSAPSVLSSGSGTSINVAPAPTSPGVSAQKLVFINAAIPSGTSTPTIVAEPLKQALPSPLSKTYVKPPEQPQIVLIPSTVGTPIKINSSPTVSQIKDVKIGLNIGQAIVNTSGSVPALPSINILQNVTSKGEEKSSKGYVLPLSTSGSSIPVSSNFMSQNITPVNESVVSASRTVNMFSGTGANVSLGSVSVTSTPASVGTRPPVLVSGNDTSSRIMPSLSNRLCTSNLGNTVAISTVKTGHLASSVLISATQPTVSPKCLTSALQIPVTVALPTPVTISPKIINTVAQAATVPGTTRSVSLSKRQSRTSVQFQSPGVSTTVPTNINTNKPQTELPSLSPNPGKIINISNFASLPNQQMSPAFLKSIPSYSSTPGVTAIHTATAPSNVTSLIGSQFSEPCIQQKIVINTSTPLAPGTQIMINGARFIVPPQGLGAGSHVLLISTNPKYGPPLVVNSGQGAQPTPVDNLAQKITLASNNSLSGQPVKHCLKSSTKIVNSLGNASSLSTIPAAPQIINPTAKVSVPPPVPTVSLTSVIKSPPATLLAKTSLVSAICSSNPPLPSNTSVFHLDTSVKKLLVSPEGAILNTINTPASKVSSVSPSLSQIVSASRNPASVFPAFQSSGLEKPDTAAS", "length": 2036 }, "evidence": [ { "id": "A0A8V0YJQ7", "url": "https://omabrowser.org/oma/group/A0A8V0YJQ7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "H3BKP8-1", "protein_name": "Bromodomain containing 10", "gene_name": "Brd10", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSVPEPPGEMERAAEEERPPPPTGEGNEEEVVVAAAARASGLVRRRSASSVDEEEEAAASETTVVAGGGCKEQELTYELQQGYRILGEFLQEKHRGLTAPFLQPLGGVAAGEEEVAEGRRSGGRGSRVPPQQPSQGMCLLKMEEKFSSGQYRGITEFVADFRLMLETCYRLHGVDHWISKQGQKLEMLLEQKLALLSRLREQERKEAEEACQKEVEEWERKLLAQAAPACMENMWEIPAIGHFLCLAQQILNLPEIVFYELERCLLMPQCNAFLSKIMTSLLSPPHRRPTLHRRPTLPYRTWEAVLRQKVQQWYTAVGQTENPDNCAEKLGLCPQFFKVLGEVNPLEERPFHELPFYQKVWLLKGLCDFVYETQKEVQDAVLGQPIHECREVILGYDYLENAYVHFPQFCGADVRIYKQRPFQAPEFPVPPIKVKRVPRIKLEKFKCDYANTSNGEHRCTKEGLPLAFKKEQEIDFDPACCPTKMNFDNHDITLEMEVKSNCDIKVHRPCEIEKTDCCKENLQKPRSPGEVTGFGEPLSPGEIRFIENQEKYGEASKIKTESNPLKENALKSCQIHINGSHIDHPDINCHKVVRDILLEHSLQSHKKLKLTKMRAKKKKKKKKKLKDVLNENLQRKREGLHSLPFKSYKPEIQNKLLIIKKKGKHKKHKSGKKSISKKAITKKRKTVTKSPAVPEFQLICTNLDELRELITKIENELKDLENSRKKSGKWYHRRQAVKELHSTLIRLLNELLPWEPKLMKAFQRNRSRLKKDYDDFRRQPDHGQFTRELWATDECEGNPEREAPKAEVSKSVDAAEPLDTLEKEQEGSDDMKLSEIGFPMARSKLLKKELPSKDIVKTLPKTLKRQSKQSSYLDDSTKELSPRKKAKLSTNETSVENLEVNMQIECLKESKPPELPTPESFASKASVPVSTLQKGTKPIQALLAKNIGNKVTLTNQLPPSTGRSVPAVEKPALSPEDTSPLKPALTCLTSTKGPLQMVYKMPCGQWLPVDLHSSSVKIQMQPMVDSKTGEKIMQQVLILPKNFVIQHKEGKAVEKEIAAPQQKGPEHCSPGPQTSASCSLVSVPVTSVSTQLPNTVLSKTSTPSSNVSARSQPLSPVASVSNALTSPVKTSQSEAGKVKSTASSTTLPQPHTSPTISSTVQPLLPATTLNESTDPGSSIPCFSQQTVDSSEAKQELKTVCIRDSQSILVRTRGGNTGVVKVQTNPEQNSPNSLSSSSVFTFTPQFQAFLVPKSTSCSASSQVAGVTTTSSLPSFSQASTSVSISCGFHPPMGKNLKSTQGQTLSSGYVGPMIEKTSYMPSSPLKPSVSSSSLLPSTTNSSVSVISISTGNFGQTNTNVIHTSTKPQQVDCITKSYPVTRSEATTAVNGDVLGETPGQKLMLVSAPSGLPSGSVPSVNTAPEPTSAGVSTQKVVFINAPVPGGASSSAIVAESLRQSLPSPLNKTYIKNPEQPQIVLIPSTVGAPIKINSSPTVSQIKDVKIGLNIGQAIINPPGNLPAMSSINILQSVMPKGEDKSSKSCISPISPNSNSAPASSNIVNHSLPAASESARTANTFSGIGASVPLSSLSVASSPASAGTRPPVLVSGNDTSSRIMPVLSNRLCPSNLGNTVAISTVKTGHLASSVLISTTQPTVSPKCLTPALQIPVTVALPTPVTTSPKIINTVPQSATIPGATRPVSLSKRQSQTSLQFQSPGTTTIVPTNANTNKPPAELSPSASPGKIVNISNVTSMPNQHMSPSLVKSTLGNNSIAGGSAIHTCSPPSNITSLAGAPFSEPCIQQKIVINTSTPLAPGTQIMMNGARFIVPPQGLGAGSHVLLISTNPKYGPPLVLNSGQSILATPVDNPVQKIIQTSNSSLSGQPLKPSVRNSPKTVNSLGSPSSLSAVHTPPHIINTPAKVCVPPAPPAALTSVIKSSPATLLAKTSLVSAISSSNPPLPSSTSVLHLDTSVKKLLVSPEGAILNTINTAAAKVSSLPSPLPPVVSASQNPASVFPAFPSSALEKPDTAAS", "length": 2027 }, "evidence": [ { "id": "A0A8V0YJQ7", "url": "https://omabrowser.org/oma/group/A0A8V0YJQ7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q5HYC2-1", "protein_name": "Uncharacterized bromodomain-containing protein 10", "gene_name": "BRD10", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSVPGTPGAMEPAGEEERPPPAAEGEDDEEEVAAAAQTSGPAHGRSASSLEDADDQEEEMEAMVIGGGCCKEQELTYELQQGYRILGEFLQEKHRGLTAPFLQPLGGVATAEEEVAEGPRSGGRGGRAFPQQPGQGMCLLQMEEKFASGQYGGITEFVADFRLMLETCYRLHGVDHWISKQGQKLEMMLEQKLALLSRHLREKTTIAVTSRGYYGLEDEKGTACTSTRRRSTPRSLAGLTSGVFESIMVQVLRQEEQLRAKEEKRLREQERKEAEEASQKEIEEWERKLLAQAAPTCMETMWEIPAIGHFLCLAQQILNLPEIVFYELERCLLMPQCNAFLSKIMTSLLSPPHRRPTLHRRPTLPYRTWEAALRQKVQQWYTAVGQTENPDNCAEKLGLCPQFFKVLGEVNPLEEKPFHELPFYQKVWLLKGLCDFVYETQKEVQDAVLGQPIHECREVILGYDYLENAYVHFPQFCGADVRIYKQRPFQAPEFPIPPIKIQRVPRIKLEKLKCDYVSTSNGEHRCSRDSLPSSFKKEQENNFDPACCPAKMILDNHDISVEMGVKSNYEIRIRRPCEIKKTDCCKENLEKPRSPGEVTGFGEPLSPGEIRFIENQEKYGEASRIKIEPSPLKENTLKSCQIHVNGSHSDHPEINCHKVVRDILLEQSLQSHKKLKLTKMRAKKKKKKKKKLKDVLNENLQRKREGLHSLAFKSYKPEIQNKLLIIKKKAKHKKHKSGKKSVSKKAITKKRKTVIKSPTVPEFQLICTNLDELRELITKIENELKDLENSRKKSGKWYHRRQAVKELHSTLIRLLNELLPWEPKLMKAFQRNRSRLKKDYDDFRRQPDHDTFNRELWTTDEGEGDLGKDSPKGEISKSIDSTEPLDILEKDHFDSDDMKLSEIDFPMARSKLLKKELPSKDLPKTLLKTLKRQSKQTDYVDDSTKELSPRKKAKLSTNETTVENLESDVQIDCFSESKHTEPSFPESFASLDSVPVSTLQKGTKPIQALLAKNIGNKVTLTNQLPPSTGRNALAVEKPVLSPPEASPIKPALTCHTNTKGPLQMVYKMPCGQWLPIDLQNSSVKIQVQPMVDPKTGEKIMQQVLILPKNFVIQHKEGKAVAKEVPPLQQKGTEQHCSSFPQTTNINSSLASVFVNSPGTVSTQLPNTAFNKTITPLSNISSARPQPLSPVTSVSNLLTPSVKTSQSEAGKAKNAVSAATFSLPSASPTISSTGQPLSSTTTLNGSTNPGSSFNCFAQQTADSSEAKQELKTVCIRDSQSILVRTRGGNTGVVKVQTNPDQNSPNTVSSSSVFTFAPQLQAFLVPKSTTSSSAFSPVAGTTTTSSLSPFSQTPTSVSIPASFAPSMGKNLKLTLGHTTGSGDLGHVIDKTSHMPSSPLKSSICSSTLLPSTTSSSVSVISISAANFGQNNANIIHTPTKQQQVDYITKSYPVTRSEATAATNGDVISGTPVQKLMLVSAPSILSSGNGTAINMTPALTSTGVSAQKLVFINAPVPSGTSTPTLVAESLKQTLPPPLHKAYVKTPEQPQIVLIPSTVGTPIKINSSPAVSQIKDVKIGLNIGQAIVNTSGTVPAIPSINILQNVTPKGEDKSSKGYILPLSTSGNSVPVSSNFVSQNITPVNESVVSSARAVNVLSVTGANLSLGSFPVTSASASAGAQPPVLVSGNDTSSRIMPILSNRLCSSSLGNTVAISTVKTGHLASSVLISTTQPVVSPKCLTSALQIPVTVALPTPATTSPKIINTVPHSAAVPGATRSVSISKRQSRTSLQFHSPGISTTVPTNVNTNKPQTELSSLSTSPGKITNTSNFASLPNQQALVKTPSYSSAPGGTTIHTASAPSNVTSLVGSQFSEPCIQQKIVINTSTPLAPGTQIMINGTRFIVPPQGLGAGSHVLLISTNPKYGAPLVLNSGQGIQSTPIDNSAQKITLASNNSLSGQPLQHPLRSPTKFINSFGNASSIPTVHTSPQLINTTAKVPVPPPVPTVSLTSVIKSPATLLAKTSLVSAICPSNPPLPSSTSVFHLDPPVKKLLVSPEGAILNTINTPASKVSSLSPSLSQIVVSASRSPASVFPAFQSSGLEKPDRAAS", "length": 2103 }, "evidence": [ { "id": "A0A8V0YJQ7", "url": "https://omabrowser.org/oma/group/A0A8V0YJQ7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 1044, "end_pos": 1046, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1093, "end_pos": 1095, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1143, "end_pos": 1145, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1157, "end_pos": 1159, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1172, "end_pos": 1174, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1188, "end_pos": 1190, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1197, "end_pos": 1199, "annotation": "n_glycosylation_sequon" }, { "start_pos": 133, "end_pos": 135, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1448, "end_pos": 1450, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1455, "end_pos": 1457, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1582, "end_pos": 1584, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1660, "end_pos": 1662, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1753, "end_pos": 1755, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1908, "end_pos": 1910, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1978, "end_pos": 1980, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2049, "end_pos": 2051, "annotation": "n_glycosylation_sequon" }, { "start_pos": 399, "end_pos": 401, "annotation": "n_glycosylation_sequon" }, { "start_pos": 654, "end_pos": 656, "annotation": "n_glycosylation_sequon" }, { "start_pos": 666, "end_pos": 668, "annotation": "n_glycosylation_sequon" }, { "start_pos": 843, "end_pos": 845, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YJQ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJQ7" }, { "id": "PF23450", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23450" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Uncharacterized bromodomain-containing protein 10 helical", "eco_id": "ECO_0000259", "start_pos": 311, "end_pos": 452, "start_aa": "Glu", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1044, "end_pos": 1046 }, { "start_pos": 1093, "end_pos": 1095 }, { "start_pos": 1143, "end_pos": 1145 }, { "start_pos": 1157, "end_pos": 1159 }, { "start_pos": 1172, "end_pos": 1174 }, { "start_pos": 1188, "end_pos": 1190 }, { "start_pos": 1197, "end_pos": 1199 }, { "start_pos": 133, "end_pos": 135 }, { "start_pos": 1448, "end_pos": 1450 }, { "start_pos": 1455, "end_pos": 1457 }, { "start_pos": 1582, "end_pos": 1584 }, { "start_pos": 1660, "end_pos": 1662 }, { "start_pos": 1753, "end_pos": 1755 }, { "start_pos": 1908, "end_pos": 1910 }, { "start_pos": 1978, "end_pos": 1980 }, { "start_pos": 2049, "end_pos": 2051 }, { "start_pos": 399, "end_pos": 401 }, { "start_pos": 654, "end_pos": 656 }, { "start_pos": 666, "end_pos": 668 }, { "start_pos": 843, "end_pos": 845 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YJR0-1", "uniprot_ac": "A0A8V0YJR0", "uniprot_id": "A0A8V0YJR0_CHICK", "mass": { "chemical_mass": 55426.0, "monoisotopic_mass": 55426.0 }, "refseq": {}, "gene_names": [ { "name": "CDC20B", "type": "recommended", "evidence": [ { "id": "A0A8V0YJR0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJR0" } ] } ], "protein_names": [ { "name": "Cell division cycle 20B", "type": "synonym", "evidence": [ { "id": "A0A8V0YJR0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJR0/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJR0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJR0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CDC20B", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJR0", "locus": { "chromosome": "Z", "start_pos": 17211059, "end_pos": 17245551, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010015114", "url": "https://www.ensembl.org/id/ENSGALG00010015114" } ] } } ], "crossref": [ { "id": "A0A8V0YJR0", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YJR0", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR001680", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001680", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020472", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020472", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033010", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033010", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036322", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036322", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056150", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056150", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YJR0", "url": "https://www.orthodb.org/?gene=A0A8V0YJR0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR19918", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19918", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19918:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19918:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF24807", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24807", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YJR0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJR0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJR0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJR0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSVLGKDPEWGREQNLQKVAEALDSDRTTYSGFKSSIKRKLKAGAPVASSPVVTRWQQRHAGGLAAVPRRALSSELCALRSAPLVGARGRTPVTNQMLKKPSIMKSAVTLSSRHTAAGLEGRNDRKTEIRKKRKCTTQLLMIQETGYSMAESDMKICENTSCIWKGCREGMQNEFRTVTIMKPSVTLEPELRLHITGLRNDYYLNILDWNLENLIAVALGSAAYIWNGRTLQGIESIELNSSSKYISSLAWIKEGTCLAVGTSDGEVQLWDIERKRRLRSMFGHLSVVGALSWNHYILSSGSRLGSIHHHDVRVAQHHIGTLCQNKQSICSLKWSLTNQLLASGSSDGTVNIWHSDPGVNVKSQPLKTIPHSSAVKAMNWCPWQSNVLATGGGMKDGILRVWDINHEKLLQSAATDSQICSLLWLPKTSELMTGQGLPENQIKIWQHPALISSSELYGHKGRVLHMALSPDQRRLFSVAADGIACLWKCHEYEESNEKK", "length": 499, "header": "tr|A0A8V0YJR0-1|A0A8V0YJR0_CHICK Isoform 1 of Cell division cycle 20B OS=Gallus gallus OX=9031 GN=CDC20B PE=3 SV=1 CANONICAL=A0A8V0YJR0-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YJR0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJR0/entry#A0A8V0YJR0-1", "sequence": { "sequence": "MSVLGKDPEWGREQNLQKVAEALDSDRTTYSGFKSSIKRKLKAGAPVASSPVVTRWQQRHAGGLAAVPRRALSSELCALRSAPLVGARGRTPVTNQMLKKPSIMKSAVTLSSRHTAAGLEGRNDRKTEIRKKRKCTTQLLMIQETGYSMAESDMKICENTSCIWKGCREGMQNEFRTVTIMKPSVTLEPELRLHITGLRNDYYLNILDWNLENLIAVALGSAAYIWNGRTLQGIESIELNSSSKYISSLAWIKEGTCLAVGTSDGEVQLWDIERKRRLRSMFGHLSVVGALSWNHYILSSGSRLGSIHHHDVRVAQHHIGTLCQNKQSICSLKWSLTNQLLASGSSDGTVNIWHSDPGVNVKSQPLKTIPHSSAVKAMNWCPWQSNVLATGGGMKDGILRVWDINHEKLLQSAATDSQICSLLWLPKTSELMTGQGLPENQIKIWQHPALISSSELYGHKGRVLHMALSPDQRRLFSVAADGIACLWKCHEYEESNEKK", "length": 499, "header": "tr|A0A8V0YJR0-1|A0A8V0YJR0_CHICK Isoform 1 of Cell division cycle 20B OS=Gallus gallus OX=9031 GN=CDC20B PE=3 SV=1 CANONICAL=A0A8V0YJR0-1" }, "locus": { "chromosome": "Z", "start_pos": 17245120, "end_pos": 17211747, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010036391.1", "url": "https://www.ensembl.org/id/ENSGALT00010036391.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021172.1", "url": "https://www.ensembl.org/id/ENSGALP00010021172.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "anaphase-promoting complex", "id": "GO:0005680", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005680", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJR0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJR0" } ], "pmid": "" }, { "name": "deuterosome", "id": "GO:0098536", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098536", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJR0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJR0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "anaphase-promoting complex-dependent catabolic process", "id": "GO:0031145", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031145", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJR0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJR0" } ], "pmid": "" }, { "name": "positive regulation of anaphase-promoting complex-dependent catabolic process", "id": "GO:1905786", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905786", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJR0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJR0" } ], "pmid": "" }, { "name": "de novo centriole assembly", "id": "GO:0097742", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097742", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJR0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJR0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "anaphase-promoting complex binding", "id": "GO:0010997", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010997", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJR0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJR0" } ], "pmid": "" }, { "name": "ubiquitin ligase activator activity", "id": "GO:1990757", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990757", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJR0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJR0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 159, "end_pos": 161, "annotation": "n_glycosylation_sequon" }, { "start_pos": 240, "end_pos": 242, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YJR0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJR0" }, { "id": "PF24807", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24807" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CDC20/Fizzy WD40", "eco_id": "ECO_0000259", "start_pos": 195, "end_pos": 487, "start_aa": "Ile", "end_aa": "Trp", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 159, "end_pos": 161 }, { "start_pos": 240, "end_pos": 242 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YJR4-1", "uniprot_ac": "A0A8V0YJR4", "uniprot_id": "A0A8V0YJR4_CHICK", "mass": { "chemical_mass": 61058.0, "monoisotopic_mass": 61058.0 }, "refseq": {}, "gene_names": [ { "name": "PGM5", "type": "recommended", "evidence": [ { "id": "A0A8V0YJR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJR4" } ] } ], "protein_names": [ { "name": "Phosphoglucomutase 5", "type": "synonym", "evidence": [ { "id": "A0A8V0YJR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJR4/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJR4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJR4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PGM5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJR4", "locus": { "chromosome": "Z", "start_pos": 26071191, "end_pos": 26138065, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010011887", "url": "https://www.ensembl.org/id/ENSGALG00010011887" } ] } } ], "crossref": [ { "id": "A0A8V0YJR4", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YJR4", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR005841", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005841", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005844", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005844", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005845", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005845", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005846", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005846", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016055", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016055", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036900", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036900", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045244", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045244", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YBG4", "url": "https://www.orthodb.org/?gene=A0A8V0YBG4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YJR4", "url": "https://www.orthodb.org/?gene=A0A8V0YJR4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22573", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22573", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22573:SF27", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22573:SF27", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02878", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02878", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02879", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02879", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02880", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02880", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24947", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24947", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YBG4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBG4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YBG4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBG4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJR4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJR4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJR4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJR4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MERNPIPVLTVQTTPYEDQRPTGGGGLRRPTGLFESERNYLPNFVQSLLSSVDLRDRQGCTMVVGSDGRYFSKTAIEIVVQMAAANGIGRLVIGQNGILSTPAVSCIIRKIKAAGGIILTASHSPGGPGGEFGVKFEVANGGPAPDVVSDKIYQISKTLEEYAICPDLRVDLSRLGRQEFDLENKFKPFRVEIVDSVDIYLNLLRNIFDFNAIRNLLTGPNQIKIRIDAMNGGAPANSAINCIPLEDFGGQRPDPNLTYATALLEAMRGGEYGFGAAFDADGDRYMILGQNGFFVNASDSLAVIAANLSCIPYFCQMGVRGFGRSMPTSTALDKVAKVMKVPVYETPTGWRYFSNLMDSGRCSLCGEESFGTGSDHLREKDGLWAVLVWLSILAARKQSVEEIVRDHWAKFGRHYYCRFDYEALEPRTAYFIMRDLEALITDKSFSHQQFAVGSSIYSVERTDSFEYIDPVDGTVTKRQGLRIVFSDASRLIFRMSASSHVRATLRIYAESYEKDPSQHNKEPQAVLSPLIAIALKISQIHERTGRKGPTVIT", "length": 553, "header": "tr|A0A8V0YJR4-1|A0A8V0YJR4_CHICK Isoform 1 of Phosphoglucomutase 5 OS=Gallus gallus OX=9031 GN=PGM5 PE=1 SV=1 CANONICAL=A0A8V0YJR4-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YBG4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJR4/entry#A0A8V0YBG4-1", "sequence": { "sequence": "MERNPIPVLTVQTTPYEDQRPTGGGGLRRPTGLFESERNYLPNFVQSLLSSVDLRDRQGCTMVVGSDGRYFSKTAIEIVVQMAAANGIGRLVIGQNGILSTPAVSCIIRKIKAAGGIILTASHSPGGPGGEFGVKFEVANGGPAPDVVSDKIYQISKTLEEYAICPDLRVDLSRLGRQEFDLENKFKPFRVEIVDSVDIYLNLLRNIFDFNAIRNLLTGPNQIKIRIDAMNGVMGPYVRRILCDELGAPANSAINCIPLEDFGGQRPDPNLTYATALLEAMRGGEYGFGAAFDADGDRYMILGQNGFFVNASDSLAVIAANLSCIPYFCQMGVRGFGRSMPTSTALDKVAKVMKVPVYETPTGWRYFSNLMDSGRCSLCGEESFGTGSDHLREKDGLWAVLVWLSILAARKQSVEEIVRDHWAKFGRHYYCRFDYEALEPRTAYFIMRDLEALITDKSFSHQQFAVGSSIYSVERTDSFEYIDPVDGTVTKRQAVLSPLIAIALKISQIHERTGRKGPTVIT", "length": 522, "header": "tr|A0A8V0YBG4-1|A0A8V0YBG4_CHICK Computationally mapped isoform of Phosphoglucomutase 5 OS=Gallus gallus OX=9031 GN=PGM5 PE=1 SV=1 CANONICAL=A0A8V0YJR4-1" }, "locus": { "chromosome": "Z", "start_pos": 26137908, "end_pos": 26072656, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028412.1", "url": "https://www.ensembl.org/id/ENSGALT00010028412.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016290.1", "url": "https://www.ensembl.org/id/ENSGALP00010016290.1" } ] } }, { "isoform_ac": "A0A8V0YJR4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJR4/entry#A0A8V0YJR4-1", "sequence": { "sequence": "MERNPIPVLTVQTTPYEDQRPTGGGGLRRPTGLFESERNYLPNFVQSLLSSVDLRDRQGCTMVVGSDGRYFSKTAIEIVVQMAAANGIGRLVIGQNGILSTPAVSCIIRKIKAAGGIILTASHSPGGPGGEFGVKFEVANGGPAPDVVSDKIYQISKTLEEYAICPDLRVDLSRLGRQEFDLENKFKPFRVEIVDSVDIYLNLLRNIFDFNAIRNLLTGPNQIKIRIDAMNGGAPANSAINCIPLEDFGGQRPDPNLTYATALLEAMRGGEYGFGAAFDADGDRYMILGQNGFFVNASDSLAVIAANLSCIPYFCQMGVRGFGRSMPTSTALDKVAKVMKVPVYETPTGWRYFSNLMDSGRCSLCGEESFGTGSDHLREKDGLWAVLVWLSILAARKQSVEEIVRDHWAKFGRHYYCRFDYEALEPRTAYFIMRDLEALITDKSFSHQQFAVGSSIYSVERTDSFEYIDPVDGTVTKRQGLRIVFSDASRLIFRMSASSHVRATLRIYAESYEKDPSQHNKEPQAVLSPLIAIALKISQIHERTGRKGPTVIT", "length": 553, "header": "tr|A0A8V0YJR4-1|A0A8V0YJR4_CHICK Isoform 1 of Phosphoglucomutase 5 OS=Gallus gallus OX=9031 GN=PGM5 PE=1 SV=1 CANONICAL=A0A8V0YJR4-1" }, "locus": { "chromosome": "Z", "start_pos": 26137908, 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"url": "https://www.uniprot.org/uniprotkb/A0A8V0YJS9/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein LOC100858131", "type": "synonym", "evidence": [ { "id": "XP_015142870", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015142870" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015142870.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015142870", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015142870" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJS9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJS9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LOC100858131", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJS9", "locus": {} } ], "crossref": [ { "id": "A0A8V0YJS9", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YJS9", "database": "AlphaFoldDB", "categories": [] }, { "id": "100858131", "url": "https://www.ncbi.nlm.nih.gov/gene/100858131", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR032770", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032770", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "KASAWNA", "url": "https://omabrowser.org/oma/group/KASAWNA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YJS3", "url": "https://www.orthodb.org/?gene=A0A8V0YJS3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YJS9", "url": "https://www.orthodb.org/?gene=A0A8V0YJS9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14343", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14343", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14343:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14343:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15057", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15057", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015142870", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015142870", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YJS3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJS3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJS3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJS3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJS9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJS9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJS9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJS9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEEVARQSGGSSQAIRAPSAASAKIISMPTSRVPCCHTASKALCGSVLPRCPLTHFPVCAWNPDSVCMPLISSARRTFIHSSPEASSFIRGARVLARREADGYYYLGHIAQEVKGSRERFLIEFDKSCTLKGKVQFRMQETPLYDILHYEDASQRSLAPGDRVLAPWEANAERFGPGTVLKVMENKKTPLAHNRKGVLVNFWNGQTKEVSSDQALWIPLPLSERIILELQMPLAARQMVVESSLDYPYIVTPGYRASGYYRWGRSGLDCWPGGLCSVQPCTKCSCRYTLVPHCCLAACKSPQPTEHQVQQDNSFIPGTCLSKEELSKKIEEQLSEVRISPSGGVSREEEENEEKSLMTENLPKDAQSCLEEDSELLGPKKSPQREMAHATMVDTAVNTDSWLMESVHKEEAGSRQQDAGTEARFEHKHGLCESRVADAPIQPSQKSTSVGASALCPFQRQSFFDQVHQSLKKDSLAIESALRVQRPRSTSSAQTGRFTNLNLLKDKSISKSVRNSASQERWKEVDLNKAKIEHKRRQEEERQLKRQQQREADAVQCQLRRNNQRQRLYQRTLQGLEKKLEHKNRALQHVALLQTARSERSKKESFLSEEENRKLSQRLQFLHTQRLKRENLLAELSERSFEREKERLNFLRSRMQSRQAVLTQDSEEQDRQQKQRQAAKRKVFQNRDHLHEKMEKEAQRHCDLQQYLREQNLLMLRALLLE", "length": 721, "header": "tr|A0A8V0YJS9-1|A0A8V0YJS9_CHICK Isoform 1 of DUF4537 domain-containing protein OS=Gallus gallus OX=9031 GN=LOC100858131 PE=4 SV=1 CANONICAL=A0A8V0YJS9-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YJS3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJS9/entry#A0A8V0YJS3-1", "sequence": { "sequence": "MEEVARQSGGSSQAIRAPSAASAKIISMPTSRVPCCHTASKALCGSVLPRCPLTHFPVCAWNPDSVCMPLISSARRTFIHSSPEASSFIRGARVLARREADGYYYLGHIAQEVKGSRERFLIEFDKSCTLKGKVQFRMQETPLYDILHYEDASQRSLAPGDRVLAPWEANAERFGPGTVLKVMENKKTPLAHNRKGVLVNFWNGQTKEVSSDQALWIPLPLSERIILELQMPLAARQMVVESSLDYPYIVTPGYRASGYYRWGRSGLDCWPGGLCSVQPCTKCSCRYTLVPHCCLAACKSPQPTEHQVQQDNSFIPGTCLSKEELSKKIEEQLSEVRISPSGGVSREEEENEEKSLMTENLPKDAQSCLEEDSELLGPKKVFVSPEWQMLQFNLPKRALLWEPVPCVLSSDKASLIKCISH", "length": 421, "header": "tr|A0A8V0YJS3-1|A0A8V0YJS9_CHICK Computationally mapped isoform of DUF4537 domain-containing protein OS=Gallus gallus OX=9031 GN=LOC100858131 PE=4 SV=1 CANONICAL=A0A8V0YJS9-1" }, "locus": { "chromosome": "1", "start_pos": 56961919, "end_pos": 56955543, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032272.1", "url": "https://www.ensembl.org/id/ENSGALT00010032272.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019062.1", "url": "https://www.ensembl.org/id/ENSGALP00010019062.1" } ] } }, { "isoform_ac": "A0A8V0YJS9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJS9/entry#A0A8V0YJS9-1", "sequence": { "sequence": "MEEVARQSGGSSQAIRAPSAASAKIISMPTSRVPCCHTASKALCGSVLPRCPLTHFPVCAWNPDSVCMPLISSARRTFIHSSPEASSFIRGARVLARREADGYYYLGHIAQEVKGSRERFLIEFDKSCTLKGKVQFRMQETPLYDILHYEDASQRSLAPGDRVLAPWEANAERFGPGTVLKVMENKKTPLAHNRKGVLVNFWNGQTKEVSSDQALWIPLPLSERIILELQMPLAARQMVVESSLDYPYIVTPGYRASGYYRWGRSGLDCWPGGLCSVQPCTKCSCRYTLVPHCCLAACKSPQPTEHQVQQDNSFIPGTCLSKEELSKKIEEQLSEVRISPSGGVSREEEENEEKSLMTENLPKDAQSCLEEDSELLGPKKSPQREMAHATMVDTAVNTDSWLMESVHKEEAGSRQQDAGTEARFEHKHGLCESRVADAPIQPSQKSTSVGASALCPFQRQSFFDQVHQSLKKDSLAIESALRVQRPRSTSSAQTGRFTNLNLLKDKSISKSVRNSASQERWKEVDLNKAKIEHKRRQEEERQLKRQQQREADAVQCQLRRNNQRQRLYQRTLQGLEKKLEHKNRALQHVALLQTARSERSKKESFLSEEENRKLSQRLQFLHTQRLKRENLLAELSERSFEREKERLNFLRSRMQSRQAVLTQDSEEQDRQQKQRQAAKRKVFQNRDHLHEKMEKEAQRHCDLQQYLREQNLLMLRALLLE", "length": 721, "header": "tr|A0A8V0YJS9-1|A0A8V0YJS9_CHICK Isoform 1 of DUF4537 domain-containing protein OS=Gallus gallus OX=9031 GN=LOC100858131 PE=4 SV=1 CANONICAL=A0A8V0YJS9-1" }, "locus": { "chromosome": "1", "start_pos": 56961919, "end_pos": 56951571, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032277.1", "url": "https://www.ensembl.org/id/ENSGALT00010032277.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019067.1", "url": "https://www.ensembl.org/id/ENSGALP00010019067.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 251, "start_aa": "Thr", "end_pos": 251, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr251", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YJS9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJS9" }, { "id": "PF15057", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15057" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "DUF4537", "eco_id": "ECO_0000259", "start_pos": 91, "end_pos": 218, "start_aa": "Gly", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 251 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YJS4-1", "uniprot_ac": "A0A8V0YJS4", "uniprot_id": "A0A8V0YJS4_CHICK", "mass": { "chemical_mass": 30829.0, "monoisotopic_mass": 30829.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Uncharacterized protein", "type": "synonym", "evidence": [ { "id": "A0A8V0YJS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJS4/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJS4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJS4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJS4", "locus": {} } ], "crossref": [ { "id": "A0A8V0YJS4", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YJS4", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR018154", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018154", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR10424", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10424", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10424:SF73", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10424:SF73", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YJS4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJS4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJS4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJS4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MHYDAWGGRMDLPIMGVLVPFTNWSWPYDNFQTQPLDEAGTEIWWKVSDSGCLLGQLESKLPTGETLCWETAAHPLPTPSQPISKYSCGENSSFPKFELQLPWDILVIEVKEEDTDVGKFPDMNITRCPEDLGCPTPIKIAMNYSFWFKFSCTPDGLWWLCGDGRARKFLPPRWKGSCTLGALVSYMYISIHNHTLPLSGILRTPWKRVKRVLNPLVEKPTGFHSFVRWYIPSLGVSELEKAVVNISATLEMIENATTDAIKALQVEVSTLR", "length": 272, "header": "tr|A0A8V0YJS4-1|A0A8V0YJS4_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0YJS4-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YJS4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJS4/entry#A0A8V0YJS4-1", "sequence": { "sequence": "MHYDAWGGRMDLPIMGVLVPFTNWSWPYDNFQTQPLDEAGTEIWWKVSDSGCLLGQLESKLPTGETLCWETAAHPLPTPSQPISKYSCGENSSFPKFELQLPWDILVIEVKEEDTDVGKFPDMNITRCPEDLGCPTPIKIAMNYSFWFKFSCTPDGLWWLCGDGRARKFLPPRWKGSCTLGALVSYMYISIHNHTLPLSGILRTPWKRVKRVLNPLVEKPTGFHSFVRWYIPSLGVSELEKAVVNISATLEMIENATTDAIKALQVEVSTLR", "length": 272, "header": "tr|A0A8V0YJS4-1|A0A8V0YJS4_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0YJS4-1" }, "locus": { "chromosome": "W", "start_pos": 2305239, "end_pos": 2304424, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028429.1", "url": "https://www.ensembl.org/id/ENSGALT00010028429.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016302.1", "url": "https://www.ensembl.org/id/ENSGALP00010016302.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 78, "start_aa": "Thr", "end_pos": 78, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr78", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 124, "end_pos": 126, "annotation": "n_glycosylation_sequon" }, { "start_pos": 143, "end_pos": 145, "annotation": "n_glycosylation_sequon" }, { "start_pos": 193, "end_pos": 195, "annotation": "n_glycosylation_sequon" }, { "start_pos": 23, "end_pos": 25, "annotation": "n_glycosylation_sequon" }, { "start_pos": 245, "end_pos": 247, "annotation": "n_glycosylation_sequon" }, { "start_pos": 255, "end_pos": 257, "annotation": "n_glycosylation_sequon" }, { "start_pos": 91, "end_pos": 93, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 78 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 124, "end_pos": 126 }, { "start_pos": 143, "end_pos": 145 }, { "start_pos": 193, "end_pos": 195 }, { "start_pos": 23, "end_pos": 25 }, { "start_pos": 245, "end_pos": 247 }, { 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"database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "LLATYSALQAVEPITQTAEVIVKTTLPIQGWVKDLTHIPKTGVAQSQTVARWVAYLSQRSRLSSSPLKEELQKILGPVTYHSETPEEIVVTCPEKSPVQEGKYPIPEDAWYTDGSSRGNPSRWRAVAYHPSTETIWLKSSYWLPILHCRQ", "length": 150, "header": "tr|A0A8V0YJT7-1|A0A8V0YJT7_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0YJT7-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YJT7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJT7/entry#A0A8V0YJT7-1", "sequence": { "sequence": "LLATYSALQAVEPITQTAEVIVKTTLPIQGWVKDLTHIPKTGVAQSQTVARWVAYLSQRSRLSSSPLKEELQKILGPVTYHSETPEEIVVTCPEKSPVQEGKYPIPEDAWYTDGSSRGNPSRWRAVAYHPSTETIWLKSSYWLPILHCRQ", "length": 150, "header": "tr|A0A8V0YJT7-1|A0A8V0YJT7_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0YJT7-1" }, "locus": { "chromosome": "W", "start_pos": 2524650, "end_pos": 2348920, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028445.1", "url": "https://www.ensembl.org/id/ENSGALT00010028445.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016318.1", "url": "https://www.ensembl.org/id/ENSGALP00010016318.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": 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0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YJU0-1", "uniprot_ac": "A0A8V0YJU0", "uniprot_id": "A0A8V0YJU0_CHICK", "mass": { "chemical_mass": 28560.0, "monoisotopic_mass": 28560.0 }, "refseq": { "ac": "XP_420702", "name": "phosducin-like protein 2 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_420702" }, "gene_names": [ { "name": "PDCL2", "type": "recommended", "evidence": [ { "id": "A0A8V0YJU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJU0" } ] }, { "name": "PDCL2", "type": "synonym", "evidence": [ { "id": "XP_420702", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_420702" } ] } ], "protein_names": [ { "name": "Phosducin like 2", "type": "synonym", "evidence": [ { "id": "A0A8V0YJU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJU0/entry#names_and_taxonomy" } ] }, { "name": "phosducin-like protein 2 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_420702", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_420702" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052535.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_420702.3. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_420702", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_420702" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJU0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJU0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PDCL2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJU0", "locus": { "chromosome": "4", "start_pos": 64574372, "end_pos": 64569032, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013321", "url": "https://www.ensembl.org/id/ENSGALG00010013321" } ] } } ], "crossref": [ { "id": "A0A8V0YJU0", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YJU0", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd02988", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02988", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "422749", "url": "https://www.ncbi.nlm.nih.gov/gene/422749", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR024253", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024253", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036249", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036249", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051498", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051498", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "DSCIQHY", "url": "https://omabrowser.org/oma/group/DSCIQHY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YJU0", "url": "https://www.orthodb.org/?gene=A0A8V0YJU0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45809", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45809", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45809:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45809:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02114", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02114", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_420702", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_420702", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YJU0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJU0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJU0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJU0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQDPNEDTEWNDVLRKFGILPPKEEPKDEIEEMVLRLQKEAEVKPYERMSLEELKEAEDDFDEADRKAIEMYRQQRLQEWKCLQRRQKYGELREISGEQYVKEVTNAPEDVWVIIHLYRSSIPMCLLVNEHLSHLAKKFPEAKFVKAAVNSCIQRYHDRCLPTILVYKSGEIKARFIGVAECGGAYLKVEELEWKLAEVGAIESDLEENPKKDIINMMTLSMQNISVHENMDTKSSDVLKPRIT", "length": 244, "header": "tr|A0A8V0YJU0-1|A0A8V0YJU0_CHICK Isoform 1 of Phosducin like 2 OS=Gallus gallus OX=9031 GN=PDCL2 PE=3 SV=1 CANONICAL=A0A8V0YJU0-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YJU0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJU0/entry#A0A8V0YJU0-1", "sequence": { "sequence": "MQDPNEDTEWNDVLRKFGILPPKEEPKDEIEEMVLRLQKEAEVKPYERMSLEELKEAEDDFDEADRKAIEMYRQQRLQEWKCLQRRQKYGELREISGEQYVKEVTNAPEDVWVIIHLYRSSIPMCLLVNEHLSHLAKKFPEAKFVKAAVNSCIQRYHDRCLPTILVYKSGEIKARFIGVAECGGAYLKVEELEWKLAEVGAIESDLEENPKKDIINMMTLSMQNISVHENMDTKSSDVLKPRIT", "length": 244, "header": "tr|A0A8V0YJU0-1|A0A8V0YJU0_CHICK Isoform 1 of Phosducin like 2 OS=Gallus gallus OX=9031 GN=PDCL2 PE=3 SV=1 CANONICAL=A0A8V0YJU0-1" }, "locus": { "chromosome": "4", "start_pos": 64574262, "end_pos": 64569088, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032042.1", "url": "https://www.ensembl.org/id/ENSGALT00010032042.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018832.1", "url": "https://www.ensembl.org/id/ENSGALP00010018832.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6B5E6-1", "protein_name": "Phosducin-like 2", "gene_name": "Pdcl2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQDPNEDTEWNEILRNFGILPPKEEPKDEIEEMVLRLQEEAMVKPYEKMTLAQLKEAEDEFDEEDIKAIEIYREKRLQEWKALTKKQKFGELREISGNQYVNEVTNAEKDLWVIIHLYRSSVPMCLVVNQHLSVLARKFPETKFVKAIVNSCIEHYHDNCLPTIFVYKNGQIEGKFIGVIECGGINLKLEELEWKLSQVGAIQTDLEENPKKGIADMMVSSIRNVSIYDSDSSGSDAEAK", "length": 240 }, "evidence": [ { "id": "A0A8V0YJU0", "url": "https://omabrowser.org/oma/group/A0A8V0YJU0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q32LN3-1", "protein_name": "Phosducin-like protein 2", "gene_name": "PDCL2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MQDPNEDTEWNEILRDFGILPPKEEPKDEIEEMVLRLQKEAMVKPYEKMTLAELKEAEDEFDDEDMKAIEIYREKRLQEWKALKKKQKFGELREISGNQYVNEVTNAEKDVWVIIHLYRSSIPLCLLVNQHLSLLARKFPETKFVKAIANSCIEHYHDNCLPTIFVYKNGQIEGKFIGIIECGGINLKLEELEWKLAEVGAIQTDLEENPKKAIVDVMVSSIRNTSIYGDSDSSNSDSEDTK", "length": 242 }, "evidence": [ { "id": "A0A8V0YJU0", "url": "https://omabrowser.org/oma/group/A0A8V0YJU0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q78Y63-1", "protein_name": "Phosducin-like protein 2", "gene_name": "Pdcl2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MQDPNEDTEWNEILRNFGILPPKEEPKDEIEEMVLRLQQEAMVKPYEKMTLAQLKEAEDEFDEEDIKAIEIYREKRLQEWKALKKKQKFGELREISGNQYVNEVTNAEKDLWVVIHLYRSSVPMCLVVNQHLSVLARKFPETKFVKAIVNSCIEHYHDNCLPTIFVYKNGQIEGKFIGIIECGGINLKLEELEWKLSEVGAIQSDLEENPKKGIADMMVSSIRNISIYDSDSSGSDTEAK", "length": 240 }, "evidence": [ { "id": "A0A8V0YJU0", "url": "https://omabrowser.org/oma/group/A0A8V0YJU0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8N4E4-1", "protein_name": "Phosducin-like protein 2", "gene_name": "PDCL2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MQDPNEDTEWNDILRDFGILPPKEESKDEIEEMVLRLQKEAMVKPFEKMTLAQLKEAEDEFDEEDMQAVETYRKKRLQEWKALKKKQKFGELREISGNQYVNEVTNAEEDVWVIIHLYRSSIPMCLLVNQHLSLLARKFPETKFVKAIVNSCIQHYHDNCLPTIFVYKNGQIEAKFIGIIECGGINLKLEELEWKLAEVGAIQTDLEENPRKDMVDMMVSSIRNTSIHDDSDSSNSDNDTK", "length": 241 }, "evidence": [ { "id": "A0A8V0YJU0", "url": "https://omabrowser.org/oma/group/A0A8V0YJU0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJU0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJU0" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJU0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJU0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "spermatid development", "id": "GO:0007286", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007286", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJU0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJU0" } ], "pmid": "" }, { "name": "protein folding", "id": "GO:0006457", "url": 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"cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 224, "end_pos": 226 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { 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"https://www.ncbi.nlm.nih.gov/protein/XP_004947735" } ] } ], "protein_names": [ { "name": "Lysosomal protein transmembrane 5", "type": "synonym", "evidence": [ { "id": "A0A8V0YKH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKH4/entry#names_and_taxonomy" } ] }, { "name": "lysosomal-associated transmembrane protein 5 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_004947735", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004947735" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052554.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004947735", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004947735" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKH4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKH4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LAPTM5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKH4", "locus": { "chromosome": "23", "start_pos": 643953, "end_pos": 658399, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013414", "url": "https://www.ensembl.org/id/ENSGALG00010013414" } ] } } ], "crossref": [ { "id": "A0A8V0YKH4", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YKH4", "database": "AlphaFoldDB", "categories": [] }, { "id": "419552", "url": "https://www.ncbi.nlm.nih.gov/gene/419552", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004687", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004687", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018396", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018396", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051115", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051115", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:419552", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419552", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YJU3", "url": "https://www.orthodb.org/?gene=A0A8V0YJU3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YKH4", "url": "https://www.orthodb.org/?gene=A0A8V0YKH4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12479", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12479", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12479:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12479:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03821", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03821", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_004947735", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004947735", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YJU3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJU3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJU3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJU3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YKH4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKH4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YKH4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKH4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTAQTKPPKCCFFNIKTATLALGIFHMVMSILLLIEYSLEVASGKGYCKDLSKDYYRIADVTTSFLLIIMLFVISFNLLFGVVKKRERLLIPFLALQVMDFLLSLLTMFSSYIQVPAMVSVSSLRHTEHLKTPFLALQLLDFCLSILTLCSSYMEVPTYLSLKSADNRGFLPALEKLPTEEYAKVMVTFTVAFIAVLFLKAYMFKCVLSCFKYIKASKREEVKVDTQAVEKAVLPSYEEALELPSKECPPPYVAV", "length": 255, "header": "tr|A0A8V0YKH4-1|A0A8V0YKH4_CHICK Isoform 1 of Lysosomal protein transmembrane 5 OS=Gallus gallus OX=9031 GN=LAPTM5 PE=3 SV=1 CANONICAL=A0A8V0YKH4-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YJU3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKH4/entry#A0A8V0YJU3-1", "sequence": { "sequence": 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"MTAQTKPPKCCFFNIKTATLALGIFHMVMSILLLIEYSLEVASGKGYCKDLSKDYYRIADVTTSFLLIIMLFVISFNLLFGVVKKRERLLIPFLALQVMDFLLSLLTMFSSYIQVPAMVSVSSLRHTEHLKTPFLALQLLDFCLSILTLCSSYMEVPTYLSLKSADNRGFLPALEKLPTEEYAKVMVTFTVAFIAVLFLKAYMFKCVLSCFKYIKASKREEVKVDTQAVEKAVLPSYEEALELPSKECPPPYVAV", "length": 255, "header": "tr|A0A8V0YKH4-1|A0A8V0YKH4_CHICK Isoform 1 of Lysosomal protein transmembrane 5 OS=Gallus gallus OX=9031 GN=LAPTM5 PE=3 SV=1 CANONICAL=A0A8V0YKH4-1" }, "locus": { "chromosome": "23", "start_pos": 658284, "end_pos": 644666, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032297.1", "url": "https://www.ensembl.org/id/ENSGALT00010032297.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019085.1", "url": "https://www.ensembl.org/id/ENSGALP00010019085.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:419552", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419552", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 8, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKH4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKH4" } ], "pmid": "" }, { "name": "endomembrane system", "id": "GO:0012505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0012505", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKH4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKH4" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKH4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKH4" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKH4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKH4" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKH4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKH4" } ], "pmid": "" }, { "name": "lysosomal membrane", "id": "GO:0005765", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005765", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKH4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKH4" } ], "pmid": "" }, { "name": "transport vesicle", "id": "GO:0030133", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030133", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKH4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKH4" } ], "pmid": "" }, { "name": "protein-containing complex", "id": "GO:0032991", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032991", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKH4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKH4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 22, "go_terms": [ { "name": "positive regulation of receptor catabolic process", "id": "GO:2000646", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000646", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKH4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKH4" } ], "pmid": "" }, { "name": "negative regulation of interleukin-2 production", "id": "GO:0032703", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032703", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKH4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKH4" } ], "pmid": "" }, { "name": "positive regulation of lysosomal membrane permeability", "id": "GO:0097214", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097214", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKH4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKH4" } ], "pmid": "" }, { "name": "positive regulation of MAPK cascade", "id": "GO:0043410", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043410", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKH4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKH4" } ], "pmid": "" }, { "name": "positive regulation of non-canonical NF-kappaB signal transduction", "id": "GO:1901224", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901224", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKH4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKH4" } ], "pmid": "" }, { "name": "negative regulation of type II interferon production", "id": "GO:0032689", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032689", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKH4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKH4" } ], "pmid": "" }, { "name": "positive regulation of interleukin-6 production", "id": "GO:0032755", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032755", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKH4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKH4" } ], "pmid": "" }, { "name": "positive regulation of protein ubiquitination", "id": "GO:0031398", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031398", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKH4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKH4" } ], "pmid": "" }, { "name": "protein targeting to lysosome", "id": "GO:0006622", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006622", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKH4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKH4" } ], "pmid": "" }, { "name": "intrinsic apoptotic signaling pathway", "id": "GO:0097193", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097193", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKH4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKH4" } ], "pmid": "" }, { "name": "Golgi to lysosome transport", "id": "GO:0090160", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090160", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKH4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKH4" } ], "pmid": "" }, { "name": "negative regulation of activated T cell proliferation", "id": "GO:0046007", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046007", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKH4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKH4" } ], "pmid": "" }, { "name": "positive regulation of tumor necrosis factor-mediated signaling pathway", "id": "GO:1903265", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903265", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKH4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKH4" } ], "pmid": "" }, { "name": "positive regulation of macrophage cytokine production", "id": "GO:0060907", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060907", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKH4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKH4" } ], "pmid": "" }, { "name": "negative regulation of T cell receptor signaling pathway", "id": "GO:0050860", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050860", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKH4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKH4" } ], "pmid": "" }, { "name": "negative regulation of B cell activation", "id": "GO:0050869", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050869", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKH4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKH4" } ], "pmid": "" }, { "name": "positive regulation of ubiquitin-dependent protein catabolic process", "id": "GO:2000060", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000060", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKH4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKH4" } ], "pmid": "" }, { "name": "positive regulation of interleukin-12 production", "id": "GO:0032735", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032735", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKH4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKH4" } ], "pmid": "" }, { "name": "regulation of lysosomal membrane permeability", "id": "GO:0097213", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097213", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKH4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKH4" } ], "pmid": "" }, { "name": "negative regulation of autophagic cell death", "id": "GO:1904093", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904093", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKH4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKH4" } ], "pmid": "" }, { "name": "defense response to tumor cell", "id": "GO:0002357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002357", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKH4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKH4" } ], "pmid": "" }, { "name": "induction of programmed cell death", "id": "GO:0012502", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0012502", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKH4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKH4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "ubiquitin protein ligase binding", "id": "GO:0031625", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031625", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKH4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKH4" } ], "pmid": "" }, { "name": "protein sequestering activity", "id": "GO:0140311", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140311", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKH4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKH4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": 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{ "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YJU4-1", "uniprot_ac": "A0A8V0YJU4", "uniprot_id": "A0A8V0YJU4_CHICK", "mass": { "chemical_mass": 38461.0, "monoisotopic_mass": 38461.0 }, "refseq": { "ac": "XP_015149384", "name": "U7 snRNA-associated Sm-like protein LSm11", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015149384" }, "gene_names": [ { "name": "LSM11", "type": "recommended", "evidence": [ { "id": "A0A8V0YJU4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJU4" } ] }, { "name": "LSM11", "type": "synonym", "evidence": [ { "id": "XP_015149384", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015149384" } ] } ], "protein_names": [ { "name": "LSM11, U7 small nuclear RNA associated", "type": "synonym", "evidence": [ { "id": "A0A8V0YJU4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJU4/entry#names_and_taxonomy" } ] }, { "name": "U7 snRNA-associated Sm-like protein LSm11", "type": "synonym", "evidence": [ { "id": "XP_015149384", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015149384" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052544.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015149384.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015149384", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015149384" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJU4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJU4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LSM11", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJU4", "locus": { "chromosome": "13", "start_pos": 10899179, "end_pos": 10906083, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012968", "url": "https://www.ensembl.org/id/ENSGALG00010012968" } ] } } ], "crossref": [ { "id": "A0A8V0YJU4", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YJU4", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd01739", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01739", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "416241", "url": "https://www.ncbi.nlm.nih.gov/gene/416241", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001163", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001163", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR010920", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010920", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034109", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034109", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039267", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039267", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047575", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047575", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR060343", "url": "https://www.ebi.ac.uk/interpro/entry/IPR060343", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:416241", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416241", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QETSECA", "url": "https://omabrowser.org/oma/group/QETSECA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YJU4", "url": "https://www.orthodb.org/?gene=A0A8V0YJU4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21415", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21415", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21415:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21415:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF28412", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF28412", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-111367", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-111367", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-73856", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-73856", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-77588", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-77588", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_015149384", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015149384", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YJU4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJU4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJU4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJU4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEEDEGAAGGAEQRHPRRRPGAERSPSPSRLDVSSSRFDPLLALYSADTPLPFPAAPCFNNLAEYESFQRGLLRPRGRRGPSARRGPSAGRSARRGPPAADPERIQRLRSLMVNAGPEQDAAGSGTARRRRAPRNVLTRMPLHEGSPLGELHRCVRDGVKINVHIRTFKGLRGVCTGFLVAFDKFWNMALTDVDETYRKPVLGKAFYAEPQLSLTRLFDRLKLQDASVKKGADSKTLSGELALTNDSQTSGWKVGSGRGREEDEREKQKRLGRGGEKKVPGDGLHLAARGEADVGSGTAHTGGATAGGTRTRSQARRKRRPKVDYQQVFTRHINQIFIRGENVLLVHLAH", "length": 350, "header": "tr|A0A8V0YJU4-1|A0A8V0YJU4_CHICK Isoform 1 of LSM11, U7 small nuclear RNA associated OS=Gallus gallus OX=9031 GN=LSM11 PE=4 SV=1 CANONICAL=A0A8V0YJU4-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YJU4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJU4/entry#A0A8V0YJU4-1", "sequence": { "sequence": "MEEDEGAAGGAEQRHPRRRPGAERSPSPSRLDVSSSRFDPLLALYSADTPLPFPAAPCFNNLAEYESFQRGLLRPRGRRGPSARRGPSAGRSARRGPPAADPERIQRLRSLMVNAGPEQDAAGSGTARRRRAPRNVLTRMPLHEGSPLGELHRCVRDGVKINVHIRTFKGLRGVCTGFLVAFDKFWNMALTDVDETYRKPVLGKAFYAEPQLSLTRLFDRLKLQDASVKKGADSKTLSGELALTNDSQTSGWKVGSGRGREEDEREKQKRLGRGGEKKVPGDGLHLAARGEADVGSGTAHTGGATAGGTRTRSQARRKRRPKVDYQQVFTRHINQIFIRGENVLLVHLAH", "length": 350, "header": "tr|A0A8V0YJU4-1|A0A8V0YJU4_CHICK Isoform 1 of LSM11, U7 small nuclear RNA associated OS=Gallus gallus OX=9031 GN=LSM11 PE=4 SV=1 CANONICAL=A0A8V0YJU4-1" }, "locus": { "chromosome": "13", "start_pos": 10906054, "end_pos": 10902129, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031112.1", "url": "https://www.ensembl.org/id/ENSGALT00010031112.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018106.1", "url": "https://www.ensembl.org/id/ENSGALP00010018106.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:416241", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416241", "resource": "KEGG Pathway" }, { "id": "R-GGA-111367", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-111367", "resource": "Reactome", "description": "SLBP independent Processing of Histone Pre-mRNAs" }, { "id": "R-GGA-73856", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-73856", "resource": "Reactome", "description": "RNA Polymerase II Transcription Termination" }, { "id": "R-GGA-77588", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-77588", "resource": "Reactome", "description": "SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs" } ], "orthologs": [ { "uniprot_canonical_ac": "E9QIK5-1", "protein_name": "U7 snRNA-associated Sm-like protein LSm11", "gene_name": "lsm11", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEEGERKSESVRCPASSQTSDQQNTTESTGQNPETDEDDVETKLDIRSDKFDPLLALYSPQVPLPYPNIKCFNNIAEYESFMKGGRGRAKPENVEKRLRKAQKGKADPERIERLKRLMVNNPVPEEGEGSGVKRPPRQRKTAKNVLTRMPLHTGSPLGQLNRCVQEKIRVKVHIRTFKGLRGVCSGFVVAFDKFWNLAMVDVDETYREPLLGQALYHEKALTITRLFEKLKVQETAALSAVERKQGDKLLKSDPRSGSSQLKDQSRRSDSRHNKEKPELSEIDKSTSSREMQKPESRPKVEYGRVHTRHVNQLFIRGENVLLVNIQQD", "length": 328 }, "evidence": [ { "id": "A0A8V0YJU4", "url": "https://omabrowser.org/oma/group/A0A8V0YJU4/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1MKH0-1", "protein_name": "U7 snRNA-associated Sm-like protein LSm11", "gene_name": "LSM11", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MEERERGARSARAGSPARPPSPRLDVSSDSFDPLLALYAPHLPPIPYPNAPCFNNVAEYESFLRTGLRSGGRGRARGAAAGSGGPAAAAGPSGRTRRRPDAPAPDPERIQRLRRLMVAKEEGDEAADARRRGPGRSRKAPRNVLTRMPLHEGSPLGELHRCIREGVKVNVHIRTFKGLRGVCTGFLVAFDKFWNMALTDVDETYRKPVLGKAYERDSSLTLTRLFDRLKLQDSSKKETDSKSAVEDSTLSRYSQTSTWKVASVWGRGDTDRSSRRRSRSVPSSLQASAREESRSELSGRTTRTEGSSAGGTFSRATTLSRGPSRKKKRKPKVDYQQVFTRHINQIFIRGENVLLVHLAQ", "length": 359 }, "evidence": [ { "id": "A0A8V0YJU4", "url": "https://omabrowser.org/oma/group/A0A8V0YJU4/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P83369-1", "protein_name": "U7 snRNA-associated Sm-like protein LSm11", "gene_name": "LSM11", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEERERGARSAGAGSPARPPSPRLDVSSDSFDPLLALYAPRLPPIPYPNAPCFNNVAEYESFLRTGVRGGGRGRGRARGAAAGSGVPAAPGPSGRTRRRPDAPAPDPERIQRLRRLMVAKEEGDGAAGAGRRGPGRSRKAPRNVLTRMPLHEGSPLGELHRCIREGVKVNVHIRTFKGLRGVCTGFLVAFDKFWNMALTDVDETYRKPVLGKAYERDSSLTLTRLFDRLKLQDSSKKEADSKSAVEDSTLSRYSQTSTWKLASVWGRADTGRGSHKRSRSVPSSLQASAREESRSELSGRTTRTDGSSVGGTFSRATTLSRGQSRKKKRKPKVDYQQVFTRHINQIFIRGENVLLVHLAQ", "length": 360 }, "evidence": [ { "id": "A0A8V0YJU4", "url": "https://omabrowser.org/oma/group/A0A8V0YJU4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8BUV6-1", "protein_name": "U7 snRNA-associated Sm-like protein LSm11", "gene_name": "Lsm11", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": 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"sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YJV2-1", "uniprot_ac": "A0A8V0YJV2", "uniprot_id": "A0A8V0YJV2_CHICK", "mass": { "chemical_mass": 39599.0, "monoisotopic_mass": 39599.0 }, "refseq": {}, "gene_names": [ { "name": "DOK5", "type": "recommended", "evidence": [ { "id": "A0A8V0YJV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJV2" } ] } ], "protein_names": [ { "name": "Docking protein 5", "type": "synonym", "evidence": [ { "id": "A0A8V0YJV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJV2/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJV2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJV2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], 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"database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037816", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037816", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050996", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050996", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YJV2", "url": "https://www.orthodb.org/?gene=A0A8V0YJV2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YRC7", "url": "https://www.orthodb.org/?gene=A0A8V0YRC7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YSY9", "url": "https://www.orthodb.org/?gene=A0A8V0YSY9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21258", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21258", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21258:SF45", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21258:SF45", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02174", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02174", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-8853659", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8853659", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YJV2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJV2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJV2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJV2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YRC7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRC7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YRC7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRC7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YSY9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSY9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YSY9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSY9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASNFNDIVKQGYVRIRSRRLGIYQRCWLVFKKASSKGPKRLEKFSDERAAYFRCYHKILCHEWSWDGMTVLYLPVNIPWWDCDVPPTALCWVTELNNVKNISRMPKSTKKHAVGIYFNDDTSKTFACESELEADEWCKVLQMECLGTRINDISLGEPDLLASGVEREQNERFNVYLMPSPNLDVHGECTLQITFENICLWDIQNPRVKLISWPLSALRRYGRDPSWFTFEAGRMCDTGEGLFIFQTRDGEAIYQKVHSAALAIAEQHERLLQSVKNSMLQMKMSERAVSLSTMVPLPRSAYWQHITRQHSTGQLYGLQDVSSPVKLHRTDTFPVYRSDHR", "length": 341, "header": "tr|A0A8V0YJV2-1|A0A8V0YJV2_CHICK Isoform 1 of Docking protein 5 OS=Gallus gallus OX=9031 GN=DOK5 PE=3 SV=1 CANONICAL=A0A8V0YJV2-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YJV2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJV2/entry#A0A8V0YJV2-1", "sequence": { "sequence": "MASNFNDIVKQGYVRIRSRRLGIYQRCWLVFKKASSKGPKRLEKFSDERAAYFRCYHKILCHEWSWDGMTVLYLPVNIPWWDCDVPPTALCWVTELNNVKNISRMPKSTKKHAVGIYFNDDTSKTFACESELEADEWCKVLQMECLGTRINDISLGEPDLLASGVEREQNERFNVYLMPSPNLDVHGECTLQITFENICLWDIQNPRVKLISWPLSALRRYGRDPSWFTFEAGRMCDTGEGLFIFQTRDGEAIYQKVHSAALAIAEQHERLLQSVKNSMLQMKMSERAVSLSTMVPLPRSAYWQHITRQHSTGQLYGLQDVSSPVKLHRTDTFPVYRSDHR", "length": 341, "header": "tr|A0A8V0YJV2-1|A0A8V0YJV2_CHICK Isoform 1 of Docking protein 5 OS=Gallus gallus OX=9031 GN=DOK5 PE=3 SV=1 CANONICAL=A0A8V0YJV2-1" }, "locus": { "chromosome": "20", "start_pos": 12630720, "end_pos": 12597044, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010036451.1", "url": "https://www.ensembl.org/id/ENSGALT00010036451.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021212.1", "url": "https://www.ensembl.org/id/ENSGALP00010021212.1" } ] } }, { "isoform_ac": "A0A8V0YRC7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJV2/entry#A0A8V0YRC7-1", "sequence": { "sequence": "MASNFNDIVKQGYVRIRSRRLGIYQRCWLVFKKASSKGPKRLEKFSDERAAYFRCYHKVTELNNVKNISRMPKSTKKHAVGIYFNDDTSKTFACESELEADEWCKVLQMECLGTRINDISLGEPDLLASGVEREQNERFNVYLMPSPNLDVHGECTLQITFENICLWDIQNPRVKLISWPLSALRRYGRDPSWFTFEAGRMCDTGEGLFIFQTRDGEAIYQKVHSAALAIAEQHERLLQSVKNSMLQMKMSERAVSLSTMVPLPRSAYWQHITRQHSTGQLYGLQAPQM", "length": 289, "header": "tr|A0A8V0YRC7-1|A0A8V0YRC7_CHICK Computationally mapped isoform of Docking protein 5 OS=Gallus gallus OX=9031 GN=DOK5 PE=3 SV=1 CANONICAL=A0A8V0YJV2-1" }, "locus": { "chromosome": "20", "start_pos": 12630720, "end_pos": 12597987, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010036448.1", "url": "https://www.ensembl.org/id/ENSGALT00010036448.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021211.1", "url": "https://www.ensembl.org/id/ENSGALP00010021211.1" } ] } }, { "isoform_ac": "A0A8V0YSY9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJV2/entry#A0A8V0YSY9-1", "sequence": { "sequence": "MASNFNDIVKQGYVRIRSRRLGIYQRCWLVFKKASSKGPKRLEKFSDERAAYFRCYHKVTELNNVKNISRMPKSTKKHAVGIYFNDDTSKTFACESELEADEWCKVLQMECLGTRINDISLGEPDLLASGVEREQNERFNVYLMPSPNLDVHGECTLQITFENICLWDIQNPRVKLISWPLSALRRYGRDPSWFTFEAGRMCDTGEGLFIFQTRDGEAIYQKVHSAALAIAEQHERLLQSVKNSMLLELDLPAGAAVLAQEQGSTKLQMKMSERAVSLSTMVPLPRSAYWQHITRQHSTGQLYGLQAPQM", "length": 310, "header": "tr|A0A8V0YSY9-1|A0A8V0YSY9_CHICK Computationally mapped isoform of Docking protein 5 OS=Gallus gallus OX=9031 GN=DOK5 PE=3 SV=1 CANONICAL=A0A8V0YJV2-1" }, "locus": { "chromosome": "20", "start_pos": 12630720, "end_pos": 12597987, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010036446.1", "url": "https://www.ensembl.org/id/ENSGALT00010036446.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021210.1", "url": "https://www.ensembl.org/id/ENSGALP00010021210.1" } ] } } ], "glycosylation": [], "phosphorylation": [], 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"UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJX1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJX1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTHASTGTGARGLASLETRKRKQRNCGNYSLLQKSLLSSSPSAAENGLKPHEEPLLRKNPRRFVIFPIQHPDIWKMYKQAQASFWTAEEVDLSKDLPHWNKLKADEKYFISHVLAFFAASDGIVNENLVARFSQEVQIPEARCFYGFQILIENVHSEMYSLLIDTYIKDPEKRDFLFNAIETMPCVKKKADWALKWIEDRESTFGERVVAFAAVEGIFFSGSFAAIFWLKKRGLMPGLTFSNELISRDEGLHCDFACLMFHYLVNRPSEERVREIIVNAVEIEQEFLTEALPVGLIGMNCTLMKQYIEFVADRLLMELGFSKVFHAENPFDFMENISLEGKTNFFEKRVSEYQRFAVMAETMDNVFTLDADF", "length": 372, "header": "tr|A0A8V0YJX1-1|A0A8V0YJX1_CHICK Isoform 1 of ribonucleoside-diphosphate reductase OS=Gallus gallus OX=9031 GN=RRM2B PE=3 SV=1 CANONICAL=A0A8V0YJX1-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YBM4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJX1/entry#A0A8V0YBM4-1", "sequence": { "sequence": 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"https://www.uniprot.org/uniprotkb/A0A8V0YJX1/entry#A0A8V0YBM9-1", "sequence": { "sequence": "MEGEGESTPEKGDAAACGEWSSSPSAAENGLKPHEEPLLRKNPRRFVIFPIQHPDIWKMYKQAQASFWTAEEVDLSKDLPHWNKLKADEKYFISHVLAFFAASDGIVNENLVARFSQEVQIPEARCFYGFQILIENVHSEMYSLLIDTYIKDPEKRDFLFNAIETMPCVKKKADWALKWIEDRESTFGERVVAFAAVEGIFFSGSFAAIFWLKKRGLMPGLTFSNELISRDEGLHCDFACLMFHYLVNRPSEERVREIIVNAVEIEQEFLTEALPVGLIGMNCTLMKQYIEFVADRLLMELGFSKVFHAENPFDFMENISLEGKTNFFEKRVSEYQRFAVMAETMDNVFTLDADF", "length": 355, "header": "tr|A0A8V0YBM9-1|A0A8V0YBM9_CHICK Computationally mapped isoform of ribonucleoside-diphosphate reductase OS=Gallus gallus OX=9031 GN=RRM2B PE=3 SV=1 CANONICAL=A0A8V0YJX1-1" }, "locus": { "chromosome": "2", "start_pos": 128675434, "end_pos": 128664616, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028495.1", "url": "https://www.ensembl.org/id/ENSGALT00010028495.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016351.1", "url": "https://www.ensembl.org/id/ENSGALP00010016351.1" } ] } }, { "isoform_ac": "A0A8V0YJX1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJX1/entry#A0A8V0YJX1-1", "sequence": { "sequence": "MTHASTGTGARGLASLETRKRKQRNCGNYSLLQKSLLSSSPSAAENGLKPHEEPLLRKNPRRFVIFPIQHPDIWKMYKQAQASFWTAEEVDLSKDLPHWNKLKADEKYFISHVLAFFAASDGIVNENLVARFSQEVQIPEARCFYGFQILIENVHSEMYSLLIDTYIKDPEKRDFLFNAIETMPCVKKKADWALKWIEDRESTFGERVVAFAAVEGIFFSGSFAAIFWLKKRGLMPGLTFSNELISRDEGLHCDFACLMFHYLVNRPSEERVREIIVNAVEIEQEFLTEALPVGLIGMNCTLMKQYIEFVADRLLMELGFSKVFHAENPFDFMENISLEGKTNFFEKRVSEYQRFAVMAETMDNVFTLDADF", "length": 372, "header": "tr|A0A8V0YJX1-1|A0A8V0YJX1_CHICK Isoform 1 of ribonucleoside-diphosphate reductase OS=Gallus gallus OX=9031 GN=RRM2B PE=3 SV=1 CANONICAL=A0A8V0YJX1-1" }, "locus": { "chromosome": "2", "start_pos": 128679736, "end_pos": 128664616, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028498.1", "url": "https://www.ensembl.org/id/ENSGALT00010028498.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016353.1", "url": "https://www.ensembl.org/id/ENSGALP00010016353.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "gga:420253", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420253", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D4ADQ1-1", "protein_name": "ribonucleoside-diphosphate reductase", "gene_name": "Rrm2b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGDPERPEAARPEEGEQLCPETKENEVRSNEEPLLRKSSRRFVIFPIQYPDIWKMYKQAQASFWTAEEVDLSKDLPHWNKLKSEEKYFISHILAFFAASDGIVNENLVERFSQEVQVPEARCFYGFQILIENVHSEMYSLLIDTYIRDPKKREFLFNAIETMPYVKKKADWALRWIADRKSTFGERVVAFAAVEGIFFSGSFAAIFWLKKRGLMPGLTFSNELISRDEGLHCDFACLMFQYLVNKPSEERVMEIIVDAVKIEQEFLTEALPVGLIGMNCVLMKQYIEFVADRLLGELGFSKIFQAENPFDFMENISLEGKTNFFEKRVSEYQRFAVMAETTDNVFTLDADF", "length": 351 }, "evidence": [ { "id": "A0A8V0YJX1", "url": "https://omabrowser.org/oma/group/A0A8V0YJX1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E1BFQ8-1", "protein_name": "ribonucleoside-diphosphate reductase", "gene_name": "RRM2B", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGDPERPEAARPQPEERLSSDTNENEAKSDEEPLLRKSSRRFVIFPIQYPDIWKMYKKAQASFWTAEEVDLSKDLPHWNKLKSEEKYFISHILAFFAASDGIVNENLVERFSQEVQVPEARCFYGFQILIENVHSEMYSLLIDTYIRDPKKREFLFNAIETMPYVKKKADWALRWIADRKSTFGERVVAFAAVEGIFFSGSFAAIFWLKKRGLMPGLTFSNELISRDEGLHCDFACLMFQYLVNKPSEERVREIIVNAVEIEQEFLTEALPVGLIGMNCVLMKQYIEFVADRLLTELGFSKVFQAENPFDFMENISLEGKTNFFEKRVSEYQRFAVMAETTDNVFTLDADF", "length": 351 }, "evidence": [ { "id": "A0A8V0YJX1", "url": "https://omabrowser.org/oma/group/A0A8V0YJX1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P50651-1", "protein_name": "Ribonucleoside-diphosphate reductase small chain A", "gene_name": "RNR2A", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MGSLKEGQGRDMEEGESEEPLLMAQNQRFTMFPIRYKSIWEMYKKAEASFWTAEEVDLSTDVQQWEALTDSEKHFISHILAFFAASDGIVLENLAARFLNDVQVPEARAFYGFQIAMENIHSEMYSLLLETFIKDSKEKDRLFNAIETIPCISKKAKWCLDWIQSPMSFAVRLVAFACVEGIFFSGSFCAIFWLKKRGLMPGLTFSNELISRDEGLHCDFACLLYSLLQKQLPLEKVYQIVHEAVEIETEFVCKALPCDLIGMNSNLMSQYIQFVADRLLVTLGCERTYKAENPFDWMEFISLQGKTNFFEKRVGEYQKASVMSNLQNGNQNYEFTTEEDF", "length": 341 }, "evidence": [ { "id": "A0A8V0YJX1", "url": "https://omabrowser.org/oma/group/A0A8V0YJX1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q6PEE3-1", "protein_name": "Ribonucleoside-diphosphate reductase subunit M2 B", "gene_name": "Rrm2b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGDPERPEAARPEKGEQLCSETEENVVRSNEEPLLRKSSRRFVIFPIQYPDIWRMYKQAQASFWTAEEVDLSKDLPHWNKLKSDEKYFISHILAFFAASDGIVNENLVERFSQEVQVPEARCFYGFQILIENVHSEMYSLLIDTYIRDPKKREFLFNAIETMPYVKKKADWALRWIADRKSTFGERVVAFAAVEGIFFSGSFAAIFWLKKRGLMPGLTFSNELISRDEGLHCDFACLMFQYLVNKPSEDRVREIIADAVQIEQEFLTEALPVGLIGMNCVLMKQYIEFVADRLLGELGFSKIFQAENPFDFMENISLEGKTNFFEKRVSEYQRFAVMAETTDNVFTLDADF", "length": 351 }, "evidence": [ { "id": "A0A8V0YJX1", "url": "https://omabrowser.org/oma/group/A0A8V0YJX1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q7LG56-1", "protein_name": "Ribonucleoside-diphosphate reductase subunit M2 B", "gene_name": "RRM2B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGDPERPEAAGLDQDERSSSDTNESEIKSNEEPLLRKSSRRFVIFPIQYPDIWKMYKQAQASFWTAEEVDLSKDLPHWNKLKADEKYFISHILAFFAASDGIVNENLVERFSQEVQVPEARCFYGFQILIENVHSEMYSLLIDTYIRDPKKREFLFNAIETMPYVKKKADWALRWIADRKSTFGERVVAFAAVEGVFFSGSFAAIFWLKKRGLMPGLTFSNELISRDEGLHCDFACLMFQYLVNKPSEERVREIIVDAVKIEQEFLTEALPVGLIGMNCILMKQYIEFVADRLLVELGFSKVFQAENPFDFMENISLEGKTNFFEKRVSEYQRFAVMAETTDNVFTLDADF", "length": 351 }, "evidence": [ { "id": "A0A8V0YJX1", "url": "https://omabrowser.org/oma/group/A0A8V0YJX1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q7ZYW0-1", "protein_name": "1.17.4.1", "gene_name": "rrm2b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MNSCTSNTPTVITGYQNGHKDVDPNSVEDEPLLRENPKRFVIFPIQYPDIWKMYKQAQASFWTVEEVDLSKDLTHWDGLKSEEKHFISHVLAFFAASDGIVNENLVQRFSQEVQLPEARSFYGFQILIENVHSEMYSMLINTYIRDLKERDYLFNAVQTMPCVRRKADWALQWISDTNSTFGERLVAFAAVEGIFFSGSFAAIYWLKKRGLMPGLTYSNELISRDEGLHCNFACLIYSYLVKKPSVDRVNDIIAKAVSIEQEFLTEALPVNLIGMNCSLMKQYIEFVADRLLTDLGLPKAYCSENPFDFMESISLEGKTNFFEKRVAEYQRLGVMSNVKDCEFTLDADF", "length": 349 }, "evidence": [ { "id": "A0A8V0YJX1", "url": "https://omabrowser.org/oma/group/A0A8V0YJX1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJX1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJX1" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJX1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJX1" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJX1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJX1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 7, "go_terms": [ { "name": "DNA repair", "id": "GO:0006281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006281", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJX1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJX1" } ], "pmid": "" }, { "name": "positive regulation of G2/M transition of mitotic cell cycle", "id": "GO:0010971", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010971", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJX1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJX1" } ], "pmid": "" }, { "name": "deoxyribonucleotide biosynthetic process", "id": "GO:0009263", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009263", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJX1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJX1" } ], "pmid": "" }, { "name": "positive regulation of G0 to G1 transition", "id": "GO:0070318", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070318", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJX1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJX1" } ], "pmid": "" }, { "name": "mitochondrial DNA replication", "id": "GO:0006264", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006264", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJX1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJX1" } ], "pmid": "" }, { "name": "ribonucleoside diphosphate metabolic process", "id": "GO:0009185", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009185", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJX1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJX1" } ], "pmid": "" }, { "name": "2'-deoxyribonucleotide biosynthetic process", "id": "GO:0009265", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009265", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJX1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJX1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJX1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJX1" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJX1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJX1" } ], "pmid": "" }, { "name": "ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor", "id": "GO:0004748", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004748", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJX1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJX1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 28, "end_pos": 30, "annotation": "n_glycosylation_sequon" }, { "start_pos": 299, "end_pos": 301, "annotation": "n_glycosylation_sequon" }, { "start_pos": 335, "end_pos": 337, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "1.17.4.1", "ec_name": "dADP + [thioredoxin]-disulfide + H2O = [thioredoxin]-dithiol + ADP.", "evidence": [ { "id": "1.17.4.1", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:1.17.4.1" }, { "id": "1.17.4.1", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=1.17.4.1" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 28, "end_pos": 30 }, { "start_pos": 299, "end_pos": 301 }, { "start_pos": 335, "end_pos": 337 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YJX7-1", "uniprot_ac": "A0A8V0YJX7", "uniprot_id": "A0A8V0YJX7_CHICK", "mass": { "chemical_mass": 104314.0, "monoisotopic_mass": 104314.0 }, "refseq": { "ac": "XP_004936079", "name": "exocyst complex component 1 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004936079" }, "gene_names": [ { "name": "EXOC1", "type": "recommended", "evidence": [ { "id": "A0A8V0YJX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJX7" } ] }, { "name": "EXOC1", "type": "synonym", "evidence": [ { "id": "XP_004936079", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004936079" } ] } ], "protein_names": [ { "name": "Exocyst complex component 1", "type": "recommended", "evidence": [ { "id": "A0A8V0YJX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJX7/entry#names_and_taxonomy" } ] }, { "name": "Exocyst complex component Sec3", "type": "synonym", "evidence": [ { "id": "A0A8V0YJX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJX7/entry#names_and_taxonomy" } ] }, { "name": "exocyst complex component 1 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_004936079", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004936079" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052535.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004936079", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004936079" } ] }, { "annotation": "Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJX7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJX7#function" }, { "database": "UniProtKB", "id": "ARBA00002660", "url": "https://www.uniprot.org/uniprotkb/ARBA00002660#function" }, { "database": "UniProtKB", "id": "A0A8V0YRB9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRB9#function" }, { "database": "UniProtKB", "id": "E1BS87", "url": "https://www.uniprot.org/uniprotkb/E1BS87#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJX7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJX7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "EXOC1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJX7", "locus": { "chromosome": "4", "start_pos": 64475080, "end_pos": 64500041, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010015143", "url": "https://www.ensembl.org/id/ENSGALG00010015143" } ] } } ], "crossref": [ { "id": "A0A8V0YJX7", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YJX7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000013778", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000013778", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd14683", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14683", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "422747", "url": "https://www.ncbi.nlm.nih.gov/gene/422747", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR019160", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019160", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028258", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028258", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048628", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048628", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YJX7", "url": "https://www.orthodb.org/?gene=A0A8V0YJX7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YRB9", "url": "https://www.orthodb.org/?gene=A0A8V0YRB9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1BS87", "url": "https://www.orthodb.org/?gene=E1BS87", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16092", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16092", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16092:SF33", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16092:SF33", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF09763", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09763", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF15277", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15277", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF20654", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF20654", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-264876", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-264876", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-5620916", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5620916", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_004936079", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004936079", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YJX7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJX7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJX7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJX7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YRB9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRB9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YRB9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRB9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BS87", "url": "https://www.uniprot.org/uniprotkb/E1BS87", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BS87-1", "url": "https://www.uniprot.org/uniprotkb/E1BS87-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTAIKHALQRDIFTPNDERLLSIVNVCKAGKKKRNCFLCATVTTERPVQVNVVKVKKSDKGDFYKRQTAWALRDLAVVDAKDAVKENPEFDLHFDKVYKWVASSAVEKNTFISCIWKLNQRYLRKKIDFINVSSQLLEESVPSGENQSVAGGDEEAVDEYQELNAREEQDIEIMMEGCEYAISNAEAFAEKLSRELQVLDGANIQSIMASEKQVNILMKLLDEALKEVDQIEIKLSSYEEMLQSVKEQMDQISESNYLIHLSYTNNVKLLSEIEFLVNHMDLAKGHIKALQEGDLTSSRGIEACTNAADALLQCMNVALHPGHDMLHAVKQQQQRFSDLREQFARRLTNHLNSVFVQQFTQTLLQLYNKSSYLSVPGHDQSSTLAQHSVELTLPNHHPFHRDLLRYAKLMEWLKNTDYGKYEGLTKNYMDYLSRLYEREIKDFFEVAKIKMTGTTKEGKKFATLPRKESAVKQETESLHGSSGKLTGSTSSLNKLSVQSSGNRRSQSSSLLDMGNMSASDLDVADRTKFDKIFEQVLSELEPLCLAEQDFISKFFKLQQHQSISGTTTNETEEMDGGNLSRSYIPGVPQTVSSEKDMIRQMMTKIFRCIEPELNNLIALGDKIDSFNSLYMLVKMSHHVWTAQNVDPASFLSTTLGNVLVTVKRNFDKCISNQMKQMDEVKISKKSKVGILPFVAEFEEFAALAESIFKNAERRGDLDKAYTKLIRAVFISVEKVANESQKTPRDVVMMENFHHIFATLSRLKISCLEAEKKEAKLKYTEHLQSYVVYSLGQPLEKLNHFFEGVEARVAQGIREEEVSYQLAFNKQELRKVIKEYPGKEVKKGLDNLYKKVDKHLCEEENLLQVVWHSMQDEFIRQYKHFEGLIARCYPGSGITMEFTIQDILDYCSSIAQSH", "length": 913, "header": "tr|A0A8V0YJX7-1|A0A8V0YJX7_CHICK Isoform 1 of Exocyst complex component 1 OS=Gallus gallus OX=9031 GN=EXOC1 PE=1 SV=1 CANONICAL=A0A8V0YJX7-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YJX7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJX7/entry#A0A8V0YJX7-1", "sequence": { "sequence": "MTAIKHALQRDIFTPNDERLLSIVNVCKAGKKKRNCFLCATVTTERPVQVNVVKVKKSDKGDFYKRQTAWALRDLAVVDAKDAVKENPEFDLHFDKVYKWVASSAVEKNTFISCIWKLNQRYLRKKIDFINVSSQLLEESVPSGENQSVAGGDEEAVDEYQELNAREEQDIEIMMEGCEYAISNAEAFAEKLSRELQVLDGANIQSIMASEKQVNILMKLLDEALKEVDQIEIKLSSYEEMLQSVKEQMDQISESNYLIHLSYTNNVKLLSEIEFLVNHMDLAKGHIKALQEGDLTSSRGIEACTNAADALLQCMNVALHPGHDMLHAVKQQQQRFSDLREQFARRLTNHLNSVFVQQFTQTLLQLYNKSSYLSVPGHDQSSTLAQHSVELTLPNHHPFHRDLLRYAKLMEWLKNTDYGKYEGLTKNYMDYLSRLYEREIKDFFEVAKIKMTGTTKEGKKFATLPRKESAVKQETESLHGSSGKLTGSTSSLNKLSVQSSGNRRSQSSSLLDMGNMSASDLDVADRTKFDKIFEQVLSELEPLCLAEQDFISKFFKLQQHQSISGTTTNETEEMDGGNLSRSYIPGVPQTVSSEKDMIRQMMTKIFRCIEPELNNLIALGDKIDSFNSLYMLVKMSHHVWTAQNVDPASFLSTTLGNVLVTVKRNFDKCISNQMKQMDEVKISKKSKVGILPFVAEFEEFAALAESIFKNAERRGDLDKAYTKLIRAVFISVEKVANESQKTPRDVVMMENFHHIFATLSRLKISCLEAEKKEAKLKYTEHLQSYVVYSLGQPLEKLNHFFEGVEARVAQGIREEEVSYQLAFNKQELRKVIKEYPGKEVKKGLDNLYKKVDKHLCEEENLLQVVWHSMQDEFIRQYKHFEGLIARCYPGSGITMEFTIQDILDYCSSIAQSH", "length": 913, "header": "tr|A0A8V0YJX7-1|A0A8V0YJX7_CHICK Isoform 1 of Exocyst complex component 1 OS=Gallus gallus OX=9031 GN=EXOC1 PE=1 SV=1 CANONICAL=A0A8V0YJX7-1" }, "locus": { "chromosome": "4", "start_pos": 64497240, "end_pos": 64475605, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010036483.1", "url": "https://www.ensembl.org/id/ENSGALT00010036483.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021238.1", "url": "https://www.ensembl.org/id/ENSGALP00010021238.1" } ] } }, { "isoform_ac": "A0A8V0YRB9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJX7/entry#A0A8V0YRB9-1", "sequence": { "sequence": "MTAIKHALQRDIFTPNDERLLSIVNVCKAGKKKRNCFLCATVTTERPVQVNVVKVKKSDKGDFYKRQTAWALRDLAVVDAKDAVKENPEFDLHFDKVYKWVASSAVEKNTFISCIWKLNQRYLRKKIDFINVSSQLLEESVPSGENQSVAGGDEEAVDEYQELNAREEQDIEIMMEGCEYAISNAEAFAEKLSRELQVLDGANIQSIMASEKQVNILMKLLDEALKEVDQIEIKLSSYEEMLQSVKEQMDQISESNYLIHLSYTNNVKLLSEIEFLVNHMDLAKGHIKALQEGDLTSSRGIEACTNAADALLQCMNVALHPGHDMLHAVKQQQQRFSDLREQFARRLTNHLNSVFVQQFTQTLLQLYNKSSYLSVPGHDQSSTLAQHSVELTLPNHHPFHRDLLRYAKLMEWLKNTDYGKYEGLTKNYMDYLSRLYEREIKDFFEVAKIKMTGTTKEGKKFGLHGSSGKLTGSTSSLNKLSVQSSGNRRSQSSSLLDMGNMSASDLDVADRTKFDKIFEQVLSELEPLCLAEQDFISKFFKLQQHQSISGTTTNETEEMDGGNLSRSYIPGVPQTVSSEKDMIRQMMTKIFRCIEPELNNLIALGDKIDSFNSLYMLVKMSHHVWTAQNVDPASFLSTTLGNVLVTVKRNFDKCISNQMKQMDEVKISKKSKVGILPFVAEFEEFAALAESIFKNAERRGDLDKAYTKLIRAVFISVEKVANESQKTPRDVVMMENFHHIFATLSRLKISCLEAEKKEAKLKYTEHLQSYVVYSLGQPLEKLNHFFEGVEARVAQGIREEEVSYQLAFNKQELRKVIKEYPGKEVKKGLDNLYKKVDKHLCEEENLLQVVWHSMQDEFIRQYKHFEGLIARCYPGSGITMEFTIQDILDYCSSIAQSH", "length": 898, "header": "tr|A0A8V0YRB9-1|A0A8V0YRB9_CHICK Computationally mapped isoform of Exocyst complex component 1 OS=Gallus gallus OX=9031 GN=EXOC1 PE=1 SV=1 CANONICAL=A0A8V0YJX7-1" }, "locus": { "chromosome": "4", "start_pos": 64497240, "end_pos": 64475605, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010036485.1", "url": "https://www.ensembl.org/id/ENSGALT00010036485.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021240.1", "url": "https://www.ensembl.org/id/ENSGALP00010021240.1" } ] } }, { "isoform_ac": "E1BS87-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJX7/entry#E1BS87-1", "sequence": { "sequence": "MTAIKHALQRDIFTPNDERLLSIVNVCKAGKKKRNCFLCATVTTERPVQVNVVKVKKSDKGDFYKRQTAWALRDLAVVDAKDAVKENPEFDLHFDKVYKWVASSAVEKNTFISCIWKLNQRYLRKKIDFINVSSQLLEELPKVAEESVPSGENQSVAGGDEEAVDEYQELNAREEQDIEIMMEGCEYAISNAEAFAEKLSRELQVLDGANIQSIMASEKQVNILMKLLDEALKEVDQIEIKLSSYEEMLQSVKEQMDQISESNYLIHLSYTNNVKLLSEIEFLVNHMDLAKGHIKALQEGDLTSSRGIEACTNAADALLQCMNVALHPGHDMLHAVKQQQQRFSDLREQFARRLTNHLNSVFVQQGHDQSSTLAQHSVELTLPNHHPFHRDLLRYAKLMEWLKNTDYGKYEGLTKNYMDYLSRLYEREIKDFFEVAKIKMTGTTKEGKKFATLPRKESAVKQETESLHGSSGKLTGSTSSLNKLSVQSSGNRRSQSSSLLDMGNMSASDLDVADRTKFDKIFEQVLSELEPLCLAEQDFISKFFKLQQHQSISGTTTNETEEMDGGNLSRSYIPGVPQTVSSEKDMIRQMMTKIFRCIEPELNNLIALGDKIDSFNSLYMLVKMSHHVWTAQNVDPASFLSTTLGNVLVTVKRNFDKCISNQMKQMDEVKISKKSKVGILPFVAEFEEFAALAESIFKNAERRGDLDKAYTKLIRAVFISVEKVANESQKTPRDVVMMENFHHIFATLSRLKISCLEAEKKEAKLKYTEHLQSYVVYSLGQPLEKLNHFFEGVEARVAQGIREEEVSYQLAFNKQELRKVIKEYPGKEVKKGLDNLYKKVDKHLCEEENLLQVVWHSMQDEFIRQYKHFEGLIARCYPGSGITMEFTIQDILDYCSSIAQSH", "length": 902, "header": "tr|E1BS87-1|E1BS87_CHICK Computationally mapped isoform of Exocyst complex component 1 OS=Gallus gallus OX=9031 GN=EXOC1 PE=1 SV=3 CANONICAL=A0A8V0YJX7-1" }, "locus": { "chromosome": "4", "start_pos": 64497240, "end_pos": 64475605, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010036487.1", "url": "https://www.ensembl.org/id/ENSGALT00010036487.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021242.1", "url": "https://www.ensembl.org/id/ENSGALP00010021242.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-264876", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-264876", "resource": "Reactome", "description": "Insulin processing" }, { "id": "R-GGA-5620916", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5620916", "resource": "Reactome", "description": "VxPx cargo-targeting to cilium" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "phosphatidylinositol-4,5-bisphosphate binding", "id": "GO:0005546", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005546", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJX7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJX7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJX7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJX7" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJX7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJX7" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJX7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJX7" } ], "pmid": "" }, { "name": "Flemming body", "id": "GO:0090543", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090543", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJX7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJX7" } ], "pmid": "" }, { "name": "exocyst", "id": "GO:0000145", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000145", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJX7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJX7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJX7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJX7" } ], "pmid": "" }, { "name": "exocytosis", "id": "GO:0006887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006887", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJX7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJX7" } ], "pmid": "" }, { "name": "Golgi to plasma membrane transport", "id": "GO:0006893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006893", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YJX7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJX7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 131, "end_pos": 133, "annotation": "n_glycosylation_sequon" }, { "start_pos": 146, "end_pos": 148, "annotation": "n_glycosylation_sequon" }, { "start_pos": 368, "end_pos": 370, "annotation": "n_glycosylation_sequon" }, { "start_pos": 515, "end_pos": 517, "annotation": "n_glycosylation_sequon" }, { "start_pos": 569, "end_pos": 571, "annotation": "n_glycosylation_sequon" }, { "start_pos": 578, "end_pos": 580, "annotation": "n_glycosylation_sequon" }, { "start_pos": 737, "end_pos": 739, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YJX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJX7" }, { "id": "SM01313", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM01313" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Exocyst complex component Sec3 PIP2-binding N-terminal", "eco_id": "ECO_0000259", "start_pos": 31, "end_pos": 122, "start_aa": "Lys", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 131, "end_pos": 133 }, { "start_pos": 146, "end_pos": 148 }, { "start_pos": 368, "end_pos": 370 }, { "start_pos": 515, "end_pos": 517 }, { "start_pos": 569, "end_pos": 571 }, { "start_pos": 578, "end_pos": 580 }, { "start_pos": 737, "end_pos": 739 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YK04-1", "uniprot_ac": "A0A8V0YK04", "uniprot_id": "A0A8V0YK04_CHICK", "mass": { "chemical_mass": 58122.0, "monoisotopic_mass": 58122.0 }, "refseq": { "ac": "XP_003641719", "name": "UDP-N-acetylhexosamine pyrophosphorylase isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003641719" }, "gene_names": [ { "name": "UAP1", "type": "recommended", "evidence": [ { "id": "A0A8V0YK04", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK04" } ] }, { "name": "UAP1", "type": "synonym", "evidence": [ { "id": "XP_003641719", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003641719" } ] } ], "protein_names": [ { "name": "UDP-N-acetylhexosamine pyrophosphorylase", "type": "recommended", "evidence": [ { "id": "A0A8V0YK04", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK04/entry#names_and_taxonomy" } ] }, { "name": "2.7.7.23", "type": "synonym", "evidence": [ { "id": "A0A8V0YK04", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK04/entry#names_and_taxonomy" } ] }, { "name": "2.7.7.83", "type": "synonym", "evidence": [ { "id": "A0A8V0YK04", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK04/entry#names_and_taxonomy" } ] }, { "name": "Protein-pyrophosphorylation enzyme", "type": "synonym", "evidence": [ { "id": "A0A8V0YK04", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK04/entry#names_and_taxonomy" } ] }, { "name": "UDP-N-acetylgalactosamine pyrophosphorylase", "type": "synonym", "evidence": [ { "id": "A0A8V0YK04", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK04/entry#names_and_taxonomy" } ] }, { "name": "UDP-N-acetylglucosamine pyrophosphorylase", "type": "synonym", "evidence": [ { "id": "A0A8V0YK04", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK04/entry#names_and_taxonomy" } ] }, { "name": "UDP-N-acetylhexosamine pyrophosphorylase isoform X1", "type": "synonym", "evidence": [ { "id": "XP_003641719", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003641719" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052539.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_003641719.4. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003641719", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003641719" } ] }, { "annotation": "Isoform AGX1 has 2 to 3 times higher activity towards galactosamine 1-phosphate (GalNAc-1-P).", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YK04", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK04#function" }, { "database": "UniProtKB", "id": "ARBA00055754", "url": "https://www.uniprot.org/uniprotkb/ARBA00055754#function" } ] }, { "annotation": "Isoform AGX2 has 8 times more activity towards glucosamine 1-phosphate (GlcNAc-1-P).", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YK04", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK04#function" }, { "database": "UniProtKB", "id": "ARBA00056409", "url": "https://www.uniprot.org/uniprotkb/ARBA00056409#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YK04", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK04" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "UAP1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK04", "locus": { "chromosome": "8", "start_pos": 3822323, "end_pos": 3827024, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013004", "url": "https://www.ensembl.org/id/ENSGALG00010013004" } ] } } ], "crossref": [ { "id": "A0A8V0YK04", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YK04", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd04193", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04193", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "424368", "url": "https://www.ncbi.nlm.nih.gov/gene/424368", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002618", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002618", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029044", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029044", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039741", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039741", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:424368", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424368", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "EREXYIM", "url": "https://omabrowser.org/oma/group/EREXYIM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YBM5", "url": "https://www.orthodb.org/?gene=A0A8V0YBM5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YK04", "url": "https://www.orthodb.org/?gene=A0A8V0YK04", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11952", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11952", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11952:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11952:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01704", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01704", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-446210", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-446210", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_003641719", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003641719", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "13509", "url": "https://www.rhea-db.org/rhea/13509", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "34363", "url": "https://www.rhea-db.org/rhea/34363", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "64104", "url": "https://www.rhea-db.org/rhea/64104", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YBM5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBM5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YBM5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBM5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YK04", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK04", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YK04-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK04-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEAAGEEDVAALRQRLAAGGQGHVLRFWPELGAAERRALAAELSAMDVAEINRFFRRARGGGGGTAAAAAAGPDARLEPVPRDVLGSASRDRRLLPGWESRGLAEIAAGRVGALLLAGGQGTRLGVPYPKGMCDVGLPSRKSLFHLQAQRLRRLQQLAEERHGTACSIPWYIMTSGRTMESTKEFFQKHRYFGLKKENVIFFQQGMLPALGFDGKILLEEKGKIAMAPDGNGGLYRALGVHGIVDDMERRGVQSVHVYCVDNILVKVADPRFIGFCLEKGADCGAKVVEKTNPTEPVGVVCRVDGVYQVVEYSEISLDTAQKRGPDGRLLFNAGNIANHYFTTSFLKDVVNTYEPQLQHHVAEKKIPHVDIETGQLVQPEKPNGIKMEKFVFDIFQFSKKFVVYEVLREDEFSPLKNADSQNGKDNPTTARHALMSLHHRWVLNAGGHFVDENGTRLPAIPRVTNGRSDAAPADGNDNLKDASDVPIQCEISPLVSYGGEGLEELVKEREFRAPLVIDEDGTHELVHNGM", "length": 530, "header": "tr|A0A8V0YK04-1|A0A8V0YK04_CHICK Isoform 1 of UDP-N-acetylhexosamine pyrophosphorylase OS=Gallus gallus OX=9031 GN=UAP1 PE=1 SV=1 CANONICAL=A0A8V0YK04-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YBM5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK04/entry#A0A8V0YBM5-1", "sequence": { "sequence": "MEAAGEEDVAALRQRLAAGGQGHVLRFWPELGAAERRALAAELSAMDVAEINRFFRRARGGGGGTAAAAAAGPDARLEPVPRDVLGSASRDRRLLPGWESRGLAEIAAGRVGALLLAGGQGTRLGVPYPKGMCDVGLPSRKSLFHLQAQRLRRLQQLAEERHGTACSIPWYIMTSGRTMESTKEFFQKHRYFGLKKENVIFFQQGMLPALGFDGKILLEEKGKIAMAPDGNGGLYRALGVHGIVDDMERRGVQSVHVYCVDNILVKVADPRFIGFCLEKGADCGAKVVEKTNPTEPVGVVCRVDGVYQVVEYSEISLDTAQKRGPDGRLLFNAGNIANHYFTTSFLKDVVNTYEPQLQHHVAEKKIPHVDIETGQLVQPEKPNGIKMEKFVFDIFQFSKKFVVYEVLREDEFSPLKNADSQNGKDNPTTARHALMSLHHRWVLNAGGHFVDENGTRLPAIPRLKDASDVPIQCEISPLVSYGGEGLEELVKEREFRAPLVIDEDGTHELVHNGM", "length": 514, "header": "tr|A0A8V0YBM5-1|A0A8V0YBM5_CHICK Computationally mapped isoform of UDP-N-acetylglucosamine pyrophosphorylase 1 OS=Gallus gallus OX=9031 GN=UAP1 PE=1 SV=1 CANONICAL=A0A8V0YK04-1" }, "locus": { "chromosome": "8", "start_pos": 3827015, "end_pos": 3822693, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031191.1", "url": "https://www.ensembl.org/id/ENSGALT00010031191.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018169.1", "url": "https://www.ensembl.org/id/ENSGALP00010018169.1" } ] } }, { "isoform_ac": "A0A8V0YK04-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK04/entry#A0A8V0YK04-1", "sequence": { "sequence": "MEAAGEEDVAALRQRLAAGGQGHVLRFWPELGAAERRALAAELSAMDVAEINRFFRRARGGGGGTAAAAAAGPDARLEPVPRDVLGSASRDRRLLPGWESRGLAEIAAGRVGALLLAGGQGTRLGVPYPKGMCDVGLPSRKSLFHLQAQRLRRLQQLAEERHGTACSIPWYIMTSGRTMESTKEFFQKHRYFGLKKENVIFFQQGMLPALGFDGKILLEEKGKIAMAPDGNGGLYRALGVHGIVDDMERRGVQSVHVYCVDNILVKVADPRFIGFCLEKGADCGAKVVEKTNPTEPVGVVCRVDGVYQVVEYSEISLDTAQKRGPDGRLLFNAGNIANHYFTTSFLKDVVNTYEPQLQHHVAEKKIPHVDIETGQLVQPEKPNGIKMEKFVFDIFQFSKKFVVYEVLREDEFSPLKNADSQNGKDNPTTARHALMSLHHRWVLNAGGHFVDENGTRLPAIPRVTNGRSDAAPADGNDNLKDASDVPIQCEISPLVSYGGEGLEELVKEREFRAPLVIDEDGTHELVHNGM", "length": 530, "header": "tr|A0A8V0YK04-1|A0A8V0YK04_CHICK Isoform 1 of UDP-N-acetylhexosamine pyrophosphorylase OS=Gallus gallus OX=9031 GN=UAP1 PE=1 SV=1 CANONICAL=A0A8V0YK04-1" }, "locus": { "chromosome": "8", "start_pos": 3827015, "end_pos": 3822693, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031189.1", "url": "https://www.ensembl.org/id/ENSGALT00010031189.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018167.1", "url": "https://www.ensembl.org/id/ENSGALP00010018167.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "gga:424368", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424368", "resource": "KEGG Pathway" }, { "id": "R-GGA-446210", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-446210", "resource": "Reactome", "description": "Synthesis of UDP-N-acetyl-glucosamine" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZF39-1", "protein_name": "UDP-N-acetylhexosamine pyrophosphorylase", "gene_name": "Uap1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MNVNDLRQRLSAAGQQHLLQFWSELSEAQQGELYMELQAMNFEELNSFFQKAVGEFDRSSHQEKVDARMEPVPRQVLGSATRDQDQLQAWESEGLSQISQNKVAVLLLAGGQGTRLGVTYPKGMYDVGLPSHKTLFQIQAERILKLQQLAEKQYGNKCTIPWYIMTSGRTMESTKEFFTKHKFFGLKKENVVFFQQGMLPAMSFDGKVILEEKNKVSMAPDGNGGLYRALAAQNIVEDMEQRGIWSIHVYCVDNILVKVADPRFIGFCIQKGADCGAKVVEKTNPTEPVGVVCRVDGVYQVVEYSEISLATAQKRSSDGRLLFNAGNIANHFFTVPFLKDVVNVYEPQLQHHVAQKKIPYVDSQGHLIKPDKPNGIKMEKFVFDIFQFAKKFVVYEVLREDEFSPLKNADSQNGKDNPTTARHALMSLHHCWVLNAGGHFIDENGSRLPAIPRSATNGKSETITADVNHNLKDANDVPIQCEISPLISYAGEGLEGYVADKDFHAPLIIDENGVHELVKNGI", "length": 522 }, "evidence": [ { "id": "A0A8V0YK04", "url": "https://omabrowser.org/oma/group/A0A8V0YK04/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YK04", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK04" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YK04", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK04" } ], "pmid": "" }, { "name": "UDP-N-acetylglucosamine diphosphorylase activity", "id": "GO:0003977", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003977", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YK04", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK04" } ], "pmid": "" }, { "name": "UDP-N-acetylgalactosamine diphosphorylase activity", "id": "GO:0052630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0052630", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YK04", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK04" } ], "pmid": "" }, { "name": "protein serine pyrophosphorylase activity", "id": "GO:0141090", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0141090", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YK04", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK04" } ], "pmid": "" }, { "name": "uridylyltransferase activity", "id": "GO:0070569", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070569", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YK04", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK04" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "UDP-N-acetylglucosamine biosynthetic process", "id": "GO:0006048", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006048", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YK04", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK04" } ], "pmid": "" }, { "name": "positive regulation of type I interferon production", "id": "GO:0032481", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032481", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YK04", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK04" } ], "pmid": "" }, { "name": "antiviral innate immune response", "id": "GO:0140374", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140374", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YK04", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK04" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 453, "end_pos": 455, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "13509", "name": "", "equation": "N-acetyl-alpha-D-glucosamine 1-phosphate + UTP + H(+) = UDP-N-acetyl-alpha-D-glucosamine + diphosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YK04-1" ], "evidence": [ { "id": "13509", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/13509" } ] }, { "id": "34363", "name": "", "equation": "N-acetyl-alpha-D-galactosamine 1-phosphate + UTP + H(+) = UDP-N-acetyl-alpha-D-galactosamine + diphosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YK04-1" ], "evidence": [ { "id": "34363", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/34363" } ] }, { "id": "64104", "name": "", "equation": "5-diphospho-1D-myo-inositol 1,2,3,4,6-pentakisphosphate + O-phospho-L-seryl-[protein] = O-diphospho-L-seryl-[protein] + 1D-myo-inositol hexakisphosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YK04-1" ], "evidence": [ { "id": "64104", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/64104" } ] }, { "id": "R-GGA-446204", "name": "GlcNAc1P is dephosphorylated to UDP-N-acetyl-glucosamine", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [ "R-ALL-532204" ], "output_participant_list": [], "enzyme_list": [ "A0A8V0YK04-1" ], "evidence": [ { "id": "R-GGA-446204", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-446204" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-532204", "participant_name": "AcGlcN1P [cytosol]", "crossref": [ { "id": "57776", "database": "ChEBI", "url": "" }, { "id": "ZINC000004096361", "database": "ZINC", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A0A8V0YK04", "gene_name": "UAP1", "activity": [ { "ec_number": "2.7.7.23", "activity": "N-acetyl-alpha-D-glucosamine 1-phosphate + UTP + H(+) = UDP-N-acetyl-alpha-D-glucosamine + diphosphate.", "evidence": [ { "id": "A0A8V0YK04", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK04" } ] }, { "ec_number": "2.7.7.83", "activity": "N-acetyl-alpha-D-galactosamine 1-phosphate + UTP + H(+) = UDP-N-acetyl-alpha-D-galactosamine + diphosphate.", "evidence": [ { "id": "A0A8V0YK04", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK04" } ] }, { "ec_number": "2.7.7.83", "activity": "", "evidence": [ { "id": "A0A8V0YK04", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK04" } ] }, { "ec_number": "2.7.7.23", "activity": "", "evidence": [ { "id": "A0A8V0YK04", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK04" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.7.7.23", "ec_name": "N-acetyl-alpha-D-glucosamine 1-phosphate + UTP + H(+) = UDP-N-acetyl-alpha-D-glucosamine + diphosphate.", "evidence": [ { "id": "2.7.7.23", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.23" }, { "id": "2.7.7.23", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.7.7.23" } ] }, { "ec_number": "2.7.7.83", "ec_name": "N-acetyl-alpha-D-galactosamine 1-phosphate + UTP + H(+) = UDP-N-acetyl-alpha-D-galactosamine + diphosphate.", "evidence": [ { "id": "2.7.7.83", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.83" }, { "id": "2.7.7.83", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.7.7.83" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 453, "end_pos": 455 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YK27-1", "uniprot_ac": "A0A8V0YK27", "uniprot_id": "A0A8V0YK27_CHICK", "mass": { "chemical_mass": 684795.0, "monoisotopic_mass": 684795.0 }, "refseq": { "ac": "XP_040511910", "name": "adhesion G-protein coupled receptor V1 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040511910" }, "gene_names": [ { "name": "ADGRV1", "type": "recommended", "evidence": [ { "id": "A0A8V0YK27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK27" } ] }, { "name": "ADGRV1", "type": "synonym", "evidence": [ { "id": "XP_040511910", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040511910" } ] } ], "protein_names": [ { "name": "Adhesion G-protein coupled receptor V1", "type": "recommended", "evidence": [ { "id": "A0A8V0YK27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK27/entry#names_and_taxonomy" } ] }, { "name": "G-protein coupled receptor 98", "type": "synonym", "evidence": [ { "id": "A0A8V0YK27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK27/entry#names_and_taxonomy" } ] }, { "name": "Very large G-protein coupled receptor 1", "type": "synonym", "evidence": [ { "id": "A0A8V0YK27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK27/entry#names_and_taxonomy" } ] }, { "name": "adhesion G-protein coupled receptor V1 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_040511910", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040511910" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052572.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040511910", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040511910" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YK27", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK27" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ADGRV1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK27", "locus": { "chromosome": "Z", "start_pos": 60230457, "end_pos": 60499020, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013001", "url": "https://www.ensembl.org/id/ENSGALG00010013001" } ] } } ], "crossref": [ { "id": "431566", "url": "https://www.ncbi.nlm.nih.gov/gene/431566", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000832", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000832", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003644", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003644", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009039", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009039", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013320", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013320", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017981", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017981", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR026919", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026919", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038081", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038081", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046338", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046338", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057244", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057244", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YBN0", "url": "https://www.orthodb.org/?gene=A0A8V0YBN0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YK19", "url": "https://www.orthodb.org/?gene=A0A8V0YK19", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YK27", "url": "https://www.orthodb.org/?gene=A0A8V0YK27", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46682", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46682", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46682:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46682:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00002", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00002", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF03160", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03160", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13385", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13385", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_040511910", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040511910", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YBN0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBN0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YBN0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBN0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YK19", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK19", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YK19-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK19-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YK27", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK27", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YK27-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK27-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSMSLGLGMHSDSLLVYLLLALVIHFTSGETEVKFSGQTEFVVNETSTTVIRLVIERTGKPANVTAIVSIHGEDTGDFFDTYAAAFIPDTETNRTVYISVCDDDLPEADETFTFYLTLPKQSAKIKLGSPKTVTVTILSNDNAFGIISFNMSALITVNEPRGRNEFVPLTLIRERGTYGIVIVTFEIKDGPNPAEEDFSPARGNITFTPGRSIVIYNLTVLDDQIPENDELFVVYLRSVEGGAEINTTKNSIQINIKKNDSPVRFIQSTYMVPEEVDILRIQVVRGKDDSGKLIGPDDCEVSVTYAIITGNSTSHAQLNLDFLDLQPNTTIVFPPLVHEIYMKFKILDDAIPEIAESFQIVLLKDTLQGDAVLVNPSTVHVTIQPNDKPYGVLSINSILFAQTVVIDEDKVSRFEGITIVRNGGTHGNVSVTWVIIRNSSDPSPVTVDLIPETGEIYFDQGQMLVTLPLNILNDDMPEEAEPYLLKLLAHTVQGGAEVSEPSELLFYIQDSDDVYGLIKFYPLENQKIQSNPTGRFLSLSFARERGTVGDVQLIYTALYIPAGDLDPDRAKDGILNISRNNILTFPEGKTHESLNIPIRNDAFLQNGAHFLIQLKGVELVNKIPLVPSVSPRLGEIRNISLRITPDIANGEIGFISNLPIILSEPEDSPATEVSIALHRDGTDGQATVFWSLKPSGVNQKAVTHDDISPFNGSVVFLSGQSDTTINITVKADDIPEMNETVLLTLDRVSVENQILKYGFTTREIIILENDDPGGVFEFSSSSRGPYSIKEGESVELQIVRARGSLVRQFLRYTVEPRDNNEFYGSTGILEFKPGEREIIITLLTRMDGIPELDEIYSVVLSSHSEMPGKLGNATMVNITILKNDDPHGIIEFLPDELTVTINESKGEDIYTAVYRVIRNQGNYGNVNVSWVVDPACTNDVYPEGGTIFFDNLEFSKNITIYSLPDEVPEEREVFLISLFSVTGGARLGNVTTAILQITGNDDPIYFAEPLTVTVQEGSVANFTVLRNGSADVAVAVHYITVNGDATAEEGDFVPSGKSSIIWFDIGEREQNLSVYINDDDIPETDETFYVLLLNSTGDTVIFKAGMATVIIEANDDSNGIFSLEPLEKAVEEGKSNTFLILRHRGHFGNVSLSWQLFDNNSALQPGEEFYETYGTVFFMDGERSKPVTLHAISDRIPEFNEFYILKLVNASGGSPGPGGQLSETNLSVIIMIPFNDDPFGVFVIDPDSQEREIVEDTLSEDDLSYITDFTIWRQQGTFGVVRLGWEILSSMFPDGLPAMIDFLLLGSFTSSVKSQPHMRRHHSGTDALYFSGKEDAFGIIGPEDPYNGNTALTSFTFSAWLIPDVRTDGYIVEKDNDNGTLYYGVKIQTNDSHVCVVLHYTAIGSYMTYMAKTAVMKYLDENTWLHLLITLDESIIEFYIDGILVLGGMKSLKGEAIVDGPGIVRIGAGINGSSRYIGLMQDVRLYERKLTHAEIYELHATPAKNDVHPVSGYLEYRQGETNKSFIVSAKDDNEEEGEELFILKLICVRGGARISQENATARLRIQKSDNANGLFGFTGSCIPETSDEGSTISCVVERTRGALDYVYIKYIISQVDSTGINYSVTDFSNSSGTITFLPWQRSEVLNLHVIDDDIPELNEYFRVTLVSAVSGDGKLGSTPTSGASIDPEKETTDISIRASDHPYGLLQFSVGLPPQPGDKMILPASSVPHITIKEEVGHIRLLVVRAQGLLGTVLVEYRTVPLTAFSPKDYQAVMGTLEFQPGERYKYITVNITDNSIPELEKTFEVELLNPGGGVAELFRNDGSGSGDGNMDFFLQTAYQHASLGIASHIIVTIEASDDAHGVFEFSAESLSVNGTEPEDGDSNIVLQIVRTHGALSEVTLHWIVDCDVSEDLISTYGNITFDVGQVRANITVQVSPDDIPELDKMFSVLIINVSSGRLGNHTNATLTVLANDDPYGLFIFSEKNRPIKVEEETKNISLTIIRLGGLLGTVVVTYRTLGDDEKPSFLPPNVVRAIQGKDYIPITGYTVFAANEREATISLPILDDDDPERSESVFVELNNTVLIEKVQDRPIVNSPRLGSASETIAHVIINANDDAFGTLQLSASTVRVAENYVGPIINVTRTGGIFADVSVKFKAMPITATAGEDYSVASSDVVLLEGETSKAVPIYIINDINPEIEESFYVQLLNQTTGGALLGSLTRAIIIIEASDDPFGSFVFQITEFTVEEPEFGSVPIDLPVIRNAGTLGNVTVHWIATIDGHLAHADLQFATGNITFAPGETFQMLLLEILADDVPEIDEVVLVVLTQASNGGAIGVDGMAKITIPANDNPYGTVFFHQSLYRIQEPLERNLLANITVRRSEGRFGQLQIFYSTSETDIVALAVEQGQDILAYYESPVQGIPDQPSKTRVNVSAASDPVYVCATQCLKEQACSAFTFSNTSGIPLCLWLTSEISPLTNTSGFWTYKKNCTSAFTLLSTQAIAGSDYQPVTRQWAIMEEGEEFANLTVIILPDDLPELDEKFTITLLKVELMNISASLKNQPTIGQPNTSTVIIMMNGDAFGVFKIYSVSPNASEKGLYVEVEERPQASVQLMIHRTEGSLGQVTVQWHVTGGTATPNVDFIGVGETLVFAEGETKKMAVLTILDDPEPEDNESIKISLIHTEGGSRILPSFDTVTVIILASDNVAGIISFHTASRSVIGREGEQLQFHIVRTAPGLGNVTVEWKIVGHNVKQNFETYSGILFFAEGMLNTTLYIHLLDDHIPEEKEEYQIILYNIKTEGVSPTGAAVLDSQGYEAVLTVEASDEPHGVLNFASTSRVVLSPEENKTIQLFINREFGSLGTINVTYATVTGLLSVSNQTEPTLAEPGDDYIPTSGSLILEEGETSAAINITILEDDIPEVQEFFLVNLTSVELIMNHSISSPPRLDVEGLASQIIIDANDGVRGVIEWEGTNFEVSESHGNLTIMAYRNRGSYGNVSVFFYAQNLEAQLGLDFYVTSRTLFFADGERNKSIVVVIFDDETPEGDEKFQLILTNPSLGLELGENTTATITILANDDAHGVLSFNNSDHFFLREQTAIHLMESVAVLNIIREPPQGIFGTVTVQYLVSEINSSEPSVDLTPSQGYVVLEEGVRLKTLHISAILDEEPEMDEHFIVTLFNPTGGARLGTRVETMITVLQNQAPLGLFSIYPVSNRTNFLIVEEANTTAYLKVSRTNGLNTSVSIEWETQSNTAFGIRDGISVLSVLQSFVEELVSGWCFFTSGEILYGVLLHEPPATFSTVYQWKGVFIPVENFTVWNPKSCMSYQISGSSYLVVSHGGAGQGASDNSVYTFMPGRRLLWMQTLSVLDTRHVKHFAVEEEDYLIIVSHPTSSSSIQIFQWNKNTFLLHHQLPLYGVLNIDLFPRGGFMYMLVSLSNTSQNMLLYQWLNNEFRRLREVPEKEVKHMESWISGSDIYLITAKESGNSSEIFIWETGQSTFRHFQSLPMHDVRIIHVFMPPSGLVHILLAGKNVTALYSWNSEANSFSIMLEAPYADHITSVIARSLNSSKSLIVLSMESKSQIYELTTVSNQSDFIPSSGELIFDPGDMAVVIAVNILDDIIPEEEECFRVWLKNPKGGAEIGSHGFVDIIIPSNDNAYGVIAFAQNSLFKQVEEMEQDSLITLNIERLVGTYGRVTVEWIANGSISDVFPASGMITFSEGQALSTITLTILADSAAELSETVAITLTRVTTVGVQDTTRGATIDPKRSRAVLTILPSDSPHGVIGWHTNSLFVKVTEPEGEMNSTTVTLQIVREQGFVGEIAVQLSTEPNLDLPLSNQATENEDYIVEKKTIVMMDNATTASVMITILPDDVPELQEGFIINITDVQLIDSLARGQPSVKRIGLEIAEITIEENDDARGIFSFSVTKDKTGTVAGYEVPPPHNILKLPVVRQAGRFGSAVLYWEAILLTAGFEDFTPSSGNLTFTDGQATGEIEITIIDDSEVEFLEIFKIVLVRVTGGARLGDETLVTVAIPPNDSPVGVFGFEEKNITVKEPQTLDDSAAIALLTVSRSPGGQGAVKVIWILEEAAEHDLTPLNGTLHFNETESQKFIVIRAVEDGILEGNETFTIQLVSAGDAEISPVNGLATIIILGDEGASGVVGIAHSFKHVLIGEPSGNYNGTALISLTRGPGIFGEIIIYWNITPPHYTEFTEISGALTMKDRQSAAVVLIQALDDDHPEEKSYYQFQLTGISDGALINESSNIANITMAASDLPYGEFTFSRELFQTTEEERWVNITIVRSRGCYGKVRLWFQIINGTAEEGIDFTPTVRELLFEPDEENKMILIEIHDDDIPEGPEDFLVMITKVELQGSGFDFTIKENGLQVDQPPIIGNISTIRVTIAKSDNAEGIIEFDPQYLLLQVEEDAGVITIPVVRKRGTYGYVTADFLSRSISALPNGVDYVIHNNSVTFHHGQNQTFIYISIIDDEESEFAEQFEIQLTGATGGAVLGLHLVSQITIAKSDSPLGIVRFLNKSRIILPNPDTPTTVSLVLERTGRLLGDTQINWDILGPNSEEILSPLNSDIGDPVNGSFYFGEGEGGLRTIHLQIYPHEDIEVQEIFVIRLSLVKGETEIDPKSNNITLIIQKFGDPNGIVQFAPESLFERNFTEPSAVEGPQNITLFLRRVQGTLGNITVHWKLYSEFDITSDFLTTEGSVVIADQQSTGEIIIYLLPDDVPELDENYIVQLISVEGGADLDEDKRISKINVFANDDPHGVFALYSDHQSILVEKDLDRYVQINVTRHAGTFGEVVIEYHIFSHQEEELIAPENERGYFTIKDGASFAVKRVPISSQAFLLLDLNFTLELINVSLVRESAKYVPKILEKAKSAVVLVPAEAANSQVGFESVILQLTNIVAGTGQAVITRKGVYGSVTVNWISGYPPELTTDFVQPGNITPSFGIVLFSSGEQSKVITFRATPNINKRESFAISLTEVHSNVSGGAQLRSGFTIAEIEPMGIFQFAFNSTFISVEEDVESVTLHVQKLFGFRSNVTKLTYQTTPGSAKPLEDFRPIHNGELIFAHFQTNAMIEISIIDDTLSEIEEYFFVNLTAVEILDFQPAKLDWSPRLNPAFSVATINILANDILHGILSLGPEFIYVEEDANNNTPNTVIINIRRTQGFTGDIEVTIKTFGGISAQNGVGLYPFENVYGKSNFTWAMEGEDFEEQSVSLTLLDGERESKVSIKIFDDDEPEGQEFFYVFLSDPKHGAQIVKGKDEYGFAAFATVIIAGSDLQNGILGFIPEVQSGLILDEDSENREVLLVVARQPNRAFEDVKVFWRVTFNETSAVLLKDGVNLENELVSVLGVTTCMAGQTMCNISIEIKPDNVPEFETYFFVELYDVSAGAALNSSARFAFVTVLESDAPHGLVYFAVGSRFAVAHKKTTLISLQVLRDSSTSVTTKVSYNMQELQKPETVGRTFISPAVAGQDFARSEGLLTFEPGQRNKFLDVTLTPETASLNPFPKRFQVVLSNPTGGARVDDVYGVANVTIVSDLGSLPFWMLIDQLHQPLDDMILQRVLQNLNVKVATETTEEQLTAVMHVIDKVTDVGEKHLLTGKSRSLFYEILCALASPKRKDTRGYSLLAEVTEKFAFSLLTEIMCGSPGERGKNILDTCPYIAIMAHNWYPQQINGHRFDGRDGDSIQVPEHLLKVSLVLSPPQEENCESIQFTEYSSQQWFLTGDKELALKNKVFSMSLKSQSSHPLKDSNEVIYRIYATGSRIVPQKSLCLLWNQAAESWLSDSGFCRVIDDTSDYVECACSHMSIYAVYAQTDDLSSYNEAFFSSGFICISGFTLAIISHLFCTRCAMFAAKLLTHMMVACLGTQISFLASAYLSQHLSEESCSALASITHYLYLCQFSWMLIQAVNFWYVLVMNDEHTERRYLLYFLLSWGLPAFIVILLLIILRGIYHHSTAQIYGLVYSDLCFIPNAYAALFTAALMPLMCLVVVFVVFVHAYQVTPQWKAYDDIFRGRTNAAEIPLVLYLFALISITWLWGGLHMAYRHLWMLVFFIIFNSLQGLYVFVVYFILHNQLCCPVKASYTVDMNGHSTPGSAFFTHGSGLPAAGGEISKSTQNLISAMEEVPADWERASLQPASQASSAFKQSPQNGNVFHPSGGFSNSSLVADEESQEFDDLIFALKTGAGLSVSDNESCHGSQDGGSMANSQIVELRRIPIADTHL", "length": 6220, "header": "tr|A0A8V0YK27-1|A0A8V0YK27_CHICK Isoform 1 of Adhesion G-protein coupled receptor V1 OS=Gallus gallus OX=9031 GN=ADGRV1 PE=3 SV=1 CANONICAL=A0A8V0YK27-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YBN0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK27/entry#A0A8V0YBN0-1", "sequence": { "sequence": "MSMSLGLGMHSDSLLVYLLLALVIHFTSGETEVKFSGQTEFVVNETSTTVIRLVIERTGKPANVTAIVSIHGEDTGDFFDTYAAAFIPDTETNRTVYISVCDDDLPEADETFTFYLTLPKQSAKIKLGSPKTVTVTILSNDNAFGIISFNMSALITVNEPRGRNEFVPLTLIRERGTYGIVIVTFEIKDGPNPAEEDFSPARGNITFTPGRSIVIYNLTVLDDQIPENDELFVVYLRSVEGGAEINTTKNSIQINIKKNDSPVRFIQSTYMVPEEVDILRIQVVRGKDDSGKLIGPDDCEVSVTYAIITGNSTSHAQLNLDFLDLQPNTTIVFPPLVHEIYMKFKILDDAIPEIAESFQIVLLKDTLQGDAVLVNPSTVHVTIQPNDKPYGVLSINSILFAQTVVIDEDKVSRFEGITIVRNGGTHGNVSVTWVIIRNSSDPSPVTVDLIPETGEIYFDQGQMLVTLPLNILNDDMPEEAEPYLLKLLAHTVQGGAEVSEPSELLFYIQDSDDVYGLIKFYPLENQKIQSNPTGRFLSLSFARERGTVGDVQLIYTALYIPAGDLDPDRAKDGILNISRNNILTFPEGKTHESLNIPIRNDAFLQNGAHFLIQLKGVELVNKIPLVPSVSPRLGEIRNISLRITPDIANGEIGFISNLPIILSEPEDSPATEVSIALHRDGTDGQATVFWSLKPSGVNQKAVTHDDISPFNGSVVFLSGQSDTTINITVKADDIPEMNETVLLTLDRVETERFVVYFGVSVENQILKYGFTTREIIILENDDPGGVFEFSSSSRGPYSIKEGESVELQIVRARGSLVRQFLRYTVEPRDNNEFYGSTGILEFKPGEREIIITLLTRMDGIPELDEIYSVVLSSHSEMPGKLGNATMVNITILKNDDPHGIIEFLPDELTVTINESKGEDIYTAVYRVIRNQGNYGNVNVSWVVDPACTNDVYPEGGTIFFDNLEFSKNITIYSLPDEVPEEREVFLISLFSVTGGARLGNVTTAILQITGNDDPIYFAEPLTVTVQEGSVANFTVLRNGSADVAVAVHYITVNGDATAEEGDFVPSGKSSIIWFDIGEREQNLSVYINDDDIPETDETFYVLLLNSTGDTVIFKAGMATVIIEANDDSNGIFSLEPLEKAVEEGKSNTFLILRHRGHFGNVSLSWQLFDNNSALQPGEEFYETYGTVFFMDGERSKPVTLHAISDRIPEFNEFYILKLVNASGGSPGPGGQLSETNLSVIIMIPFNDDPFGVFVIDPDSQEREIVEDTLSEDDLSYITDFTIWRQQGTFGVVRLGWEILSSMFPDGLPAMIDFLLLGSFTSSVKSQPHMRRHHSGTDALYFSGKEDAFGIIGPEDPYNGNTALTSFTFSAWLIPDVRTDGYIVEKDNDNGTLYYGVKIQTNDSHVCVVLHYTAIGSYMTYMAKTAVMKYLDENTWLHLLITLDESIIEFYIDGILVLGGMKSLKGEAIVDGPGIVRIGAGINGSSRYIGLMQDVRLYERKLTHAEIYELHATPAKNDVHPVSGYLEYRQGETNKSFIVSAKDDNEEEGEELFILKLICVRGGARISQENATARLRIQKSDNANGLFGFTGSCIPETSDEGSTISCVVERTRGALDYVYIKYIISQVDSTGINYSVTDFSNSSGTITFLPWQRSEVLNLHVIDDDIPELNEYFRVTLVSAVSGDGKLGSTPTSGASIDPEKETTDISIRASDHPYGLLQFSVGLPPQPGDKMILPASSVPHITIKEEVGHIRLLVVRAQGLLGTVLVEYRTVPLTAFSPKDYQAVMGTLEFQPGERYKYITVNITDNSIPELEKTFEVELLNPGGGVAELFRNDGSGSGDGNMDFFLQTAYQHASLGIASHIIVTIEASDDAHGVFEFSAESLSVNGTEPEDGDSNIVLQIVRTHGALSEVTLHWIVDCDVSEDLISTYGNITFDVGQVRANITVQVSPDDIPELDKMFSVLIINVSSGRLGNHTNATLTVLANDDPYGLFIFSEKNRPIKVEEETKNISLTIIRLGGLLGTVVVTYRTLGDDEKPSFLPPNVVRAIQGKDYIPITGYTVFAANEREATISLPILDDDDPERSESVFVELNNTVLIEKVQDRPIVNSPRLGSASETIAHVIINANDDAFGTLQLSASTVRVAENYVGPIINVTRTGGIFADVSVKFKAMPITATAGEDYSVASSDVVLLEGETSKAVPIYIINDINPEIEESFYVQLLNQTTGGALLGSLTRAIIIIEASDDPFGSFVFQITEFTVEEPEFGSVPIDLPVIRNAGTLGNVTVHWIATIDGHLAHADLQFATGNITFAPGETFQMLLLEILADDVPEIDEVVLVVLTQASNGGAIGVDGMAKITIPANDNPYGTVFFHQSLYRIQEPLERNLLANITVRRSEGRFGQLQIFYSTSETDIVALAVEQGQDILAYYESPVQGIPDQPSKTRVNVSAASDPVYVCATQCLKEQACSAFTFSNTSGIPLCLWLTSEISPLTNTSGFWTYKKNCTSAFTLLSTQAIAGSDYQPVTRQWAIMEEGEEFANLTVIILPDDLPELDEKFTITLLKVELMNISASLKNQPTIGQPNTSTVIIMMNGDAFGVFKIYSVSPNASEKGLYVEVEERPQASVQLMIHRTEGSLGQVTVQWHVTGGTATPNVDFIGVGETLVFAEGETKKMAVLTILDDPEPEDNESIKISLIHTEGGSRILPSFDTVTVIILASDNVAGIISFHTASRSVIGREGEQLQFHIVRTAPGLGNVTVEWKIVGHNVKQNFETYSGILFFAEGMLNTTLYIHLLDDHIPEEKEEYQIILYNIKTEGVSPTGAAVLDSQGYEAVLTVEASDEPHGVLNFASTSRVVLSPEENKTIQLFINREFGSLGTINVTYATVTGLLSVSNQTEPTLAEPGDDYIPTSGSLILEEGETSAAINITILEDDIPEVQEFFLVNLTSVELIMNHSISSPPRLDVEGLASQIIIDANDGVRGVIEWEGTNFEVSESHGNLTIMAYRNRGSYGNVSVFFYAQNLEAQLGLDFYVTSRTLFFADGERNKSIVVVIFDDETPEGDEKFQLILTNPSLGLELGENTTATITILANDDAHGVLSFNNSDHFFLREQTAIHLMESVAVLNIIREPPQGIFGTVTVQYLVSEINSSEPSVDLTPSQGYVVLEEGVRLKTLHISAILDEEPEMDEHFIVTLFNPTGGARLGTRVETMITVLQNQAPLGLFSIYPVSNRTNFLIVEEANTTAYLKVSRTNGLNTSVSIEWETQSNTAFGIRDGISVLSVLQSFVEELVSGWCFFTSGEILYGVLLHEPPATFSTVYQWKGVFIPVENFTVWNPKSCMSYQISGSSYLVVSHGGAGQGASDNSVYTFMPGRRLLWMQTLSVLDTRHVKHFAVEEEDYLIIVSHPTSSSSIQIFQWNKNTFLLHHQLPLYGVLNIDLFPRGGFMYMLVSLSNTSQNMLLYQWLNNEFRRLREVPEKEVKHMESWISGSDIYLITAKESGNSSEIFIWETGQSTFRHFQSLPMHDVRIIHVFMPPSGLVHILLAGKNVTALYSWNSEANSFSIMLEAPYADHITSVIARSLNSSKSLIVLSMESKSQIYELTTVSNQSDFIPSSGELIFDPGDMAVVIAVNILDDIIPEEEECFRVWLKNPKGGAEIGSHGFVDIIIPSNDNAYGVIAFAQNSLFKQVEEMEQDSLITLNIERLVGTYGRVTVEWIANGSISDVFPASGMITFSEGQALSTITLTILADSAAELSETVAITLTRVTTVGVQDTTRGATIDPKRSRAVLTILPSDSPHGVIGWHTNSLFVKVTEPEGEMNSTTVTLQIVREQGFVGEIAVQLSTEPNLDLPLSNQATENEDYIVEKKTIVMMDNATTASVMITILPDDVPELQEGFIINITDVQLIDSLARGQPSVKRIGLEIAEITIEENDDARGIFSFSVTKDKTGTVAGYEVPPPHNILKLPVVRQAGRFGSAVLYWEAILLTAGFEDFTPSSGNLTFTDGQATGEIEITIIDDSEVEFLEIFKIVLVRVTGGARLGDETLVTVAIPPNDSPVGVFGFEEKNITVKEPQTLDDSAAIALLTVSRSPGGQGAVKVIWILEEAAEHDLTPLNGTLHFNETESQKFIVIRAVEDGILEGNETFTIQLVSAGDAEISPVNGLATIIILGDEGASGVVGIAHSFKHVLIGEPSGNYNGTALISLTRGPGIFGEIIIYWNITPPHYTEFTEISGALTMKDRQSAAVVLIQALDDDHPEEKSYYQFQLTGISDGALINESSNIANITMAASDLPYGEFTFSRELFQTTEEERWVNITIVRSRGCYGKVRLWFQIINGTAEEGIDFTPTVRELLFEPDEENKMILIEIHDDDIPEGPEDFLVMITKVELQGSGFDFTIKENGLQVDQPPIIGNISTIRVTIAKSDNAEGIIEFDPQYLLLQVEEDAGVITIPVVRKRGTYGYVTADFLSRSISALPNGVDYVIHNNSVTFHHGQNQTFIYISIIDDEESEFAEQFEIQLTGATGGAVLGLHLVSQITIAKSDSPLGIVRFLNKSRIILPNPDTPTTVSLVLERTGRLLGDTQINWDILGPNSEEILSPLNSDIGDPVNGSFYFGEGEGGLRTIHLQIYPHEDIEVQEIFVIRLSLVKGETEIDPKSNNITLIIQKFGDPNGIVQFAPESLFERNFTEPSAVEGPQNITLFLRRVQGTLGNITVHWKLYSEFDITSDFLTTEGSVVIADQQSTGEIIIYLLPDDVPELDENYIVQLISVEGGADLDEDKRISKINVFANDDPHGVFALYSDHQSILVEKDLDRYVQINVTRHAGTFGEVVIEYHIFSHQEEELIAPENERGYFTIKDGASFAVKRVPISSQAFLLLDLNFTLELINVSLVRESAKYVPKILEKAKSAVVLVPAEAANSQVGFESVILQLTNIVAGTGQAVITRKGVYGSVTVNWISGYPPELTTDFVQPGNITPSFGIVLFSSGEQSKVITFRATPNINKRESFAISLTEVHSNVSGGAQLS", "length": 5002, "header": "tr|A0A8V0YBN0-1|A0A8V0YBN0_CHICK Computationally mapped isoform of Adhesion G-protein coupled receptor V1 OS=Gallus gallus OX=9031 GN=ADGRV1 PE=3 SV=1 CANONICAL=A0A8V0YK27-1" }, "locus": { "chromosome": "Z", "start_pos": 60491049, "end_pos": 60385435, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031196.1", "url": "https://www.ensembl.org/id/ENSGALT00010031196.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018174.1", "url": "https://www.ensembl.org/id/ENSGALP00010018174.1" } ] } }, { "isoform_ac": "A0A8V0YK19-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK27/entry#A0A8V0YK19-1", "sequence": { "sequence": "MSMSLGLGMHSDSLLVYLLLALVIHFTSGETEVKFSGQTEFVVNETSTTVIRLVIERTGKPANVTAIVSIHGEDTGDFFDTYAAAFIPDTETNRTVYISVCDDDLPEADETFTFYLTLPKQSAKIKLGSPKTVTVTILSNDNAFGIISFNMSALITVNEPRGRNEFVPLTLIRERGTYGIVIVTFEIKDGPNPAEEDFSPARGNITFTPGRSIVIYNLTVLDDQIPENDELFVVYLRSVEGGAEINTTKNSIQINIKKNDSPVRFIQSTYMVPEEVDILRIQVVRGKDDSGKLIGPDDCEVSVTYAIITGNSTSHAQLNLDFLDLQPNTTIVFPPLVHEIYMKFKILDDAIPEIAESFQIVLLKDTLQGDAVLVNPSTVHVTIQPNDKPYGVLSINSILFAQTVVIDEDKVSRFEGITIVRNGGTHGNVSVTWVIIRNSSDPSPVTVDLIPETGEIYFDQGQMLVTLPLNILNDDMPEEAEPYLLKLLAHTVQGGAEVSEPSELLFYIQDSDDVYGLIKFYPLENQKIQSNPTGRFLSLSFARERGTVGDVQLIYTALYIPAGDLDPDRAKDGILNISRNNILTFPEGKTHESLNIPIRNDAFLQNGAHFLIQLKGVELVNKIPLVPSVSPRLGEIRNISLRITPDIANGEIGFISNLPIILSEPEDSPATEVSIALHRDGTDGQATVFWSLKPSGVNQKAVTHDDISPFNGSVVFLSGQSDTTINITVKADDIPEMNETVLLTLDRVETERFVVYFGVSVENQILKYGFTTREIIILENDDPGGVFEFSSSSRGPYSIKEGESVELQIVRARGSLVRQFLRYTVEPRDNNEFYGSTGILEFKPGEREIIITLLTRMDGIPELDEIYSVVLSSHSEMPGKLGNATMVNITILKNDDPHGIIEFLPDELTVTINESKGEDIYTAVYRVIRNQGNYGNVNVSWVVDPACTNDVYPEGGTIFFDNLEFSKNITIYSLPDEVPEEREVFLISLFSVTGGARLGNVTTAILQITGNDDPIYFAEPLTVTVQEGSVANFTVLRNGSADVAVAVHYITVNGDATAEEGDFVPSGKSSIIWFDIGEREQNLSVYINDDDIPETDETFYVLLLNSTGDTVIFKAGMATVIIEANDDSNGIFSLEPLEKAVEEGKSNTFLILRHRGHFGNVSLSWQLFDNNSALQPGEEFYETYGTVFFMDGERSKPVTLHAISDRIPEFNEFYILKLVNASGGSPGPGGQLSETNLSVIIMIPFNDDPFGVFVIDPDSQEREIVEDTLSEDDLSYITDFTIWRQQGTFGVVRLGWEILSSMFPDGLPAMIDFLLLGSFTSSVKSQPHMRRHHSGTDALYFSGKEDAFGIIGPEDPYNGNTALTSFTFSAWLIPDVRTDGYIVEKDNDNGTLYYGVKIQTNDSHVCVVLHYTAIGSYMTYMAKTAVMKYLDENTWLHLLITLDESIIEFYIDGILVLGGMKSLKGEAIVDGPGIVRIGAGINGSSRYIGLMQDVRLYERKLTHAEIYELHATPAKNDVHPVSGYLEYRQGETNKSFIVSAKDDNEEEGEELFILKLICVRGGARISQENATARLRIQKSDNANGLFGFTGSCIPETSDEGSTISCVVERTRGALDYVYIKYIISQVDSTGINYSVTDFSNSSGTITFLPWQRSEVLNLHVIDDDIPELNEYFRVTLVSAVSGDGKLGSTPTSGASIDPEKETTDISIRASDHPYGLLQFSVGLPPQPGDKMILPASSVPHITIKEEVGHIRLLVVRAQGLLGTVLVEYRTVPLTAFSPKDYQAVMGTLEFQPGERYKYITVNITDNSIPELEKTFEVELLNPGGGVAELFRNDGSGSGDGNMDFFLQTAYQHASLGIASHIIVTIEASDDAHGVFEFSAESLSVNGTEPEDGDSNIVLQIVRTHGALSEVTLHWIVDCDVSEDLISTYGNITFDVGQVRANITVQVSPDDIPELDKMFSVLIINVSSGRLGNHTNATLTVLANDDPYGLFIFSEKNRPIKVEEETKNISLTIIRLGGLLGTVVVTYRTLGDDEKPSFLPPNVVRAIQGKDYIPITGYTVFAANEREATISLPILDDDDPERSESVFVELNNTVLIEKVQDRPIVNSPRLGSASETIAHVIINANDDAFGTLQLSASTVRVAENYVGPIINVTRTGGIFADVSVKFKAMPITATAGEDYSVASSDVVLLEGETSKAVPIYIINDINPEIEESFYVQLLNQTTGGALLGSLTRAIIIIEASDDPFGSFVFQITEFTVEEPEFGSVPIDLPVIRNAGTLGNVTVHWIATIDGHLAHADLQFATGNITFAPGETFQMLLLEILADDVPEIDEVVLVVLTQASNGGAIGVDGMAKITIPANDNPYGTVFFHQSLYRIQEPLERNLLANITVRRSEGRFGQLQIFYSTSETDIVALAVEQGQDILAYYESPVQGIPDQPSKTRVNVSAASDPVYVCATQCLKEQACSAFTFSNTSGIPLCLWLTSEISPLTNTSGFWTYKKNCTSAFTLLSTQAIAGSDYQPVTRQWAIMEEGEEFANLTVIILPDDLPELDEKFTITLLKVELMNISASLKNQPTIGQPNTSTVIIMMNGDAFGVFKIYSVSPNASEKGLYVEVEERPQASVQLMIHRTEGSLGQVTVQWHVTGGTATPNVDFIGVGETLVFAEGETKKMAVLTILDDPEPEDNESIKISLIHTEGGSRILPSFDTVTVIILASDNVAGIISFHTASRSVIGREGEQLQFHIVRTAPGLGNVTVEWKIVGHNVKQNFETYSGILFFAEGMLNTTLYIHLLDDHIPEEKEEYQIILYNIKTEGVSPTGAAVLDSQGYEAVLTVEASDEPHGVLNFASTSRVVLSPEENKTIQLFINREFGSLGTINVTYATVTGLLSVSNQTEPTLAEPGDDYIPTSGSLILEEGETSAAINITILEDDIPEVQEFFLVNLTSVELIMNHSISSPPRLDVEGLASQIIIDANDGVRGVIEWEGTNFEVSESHGNLTIMAYRNRGSYGNVSVFFYAQNLEAQLGLDFYVTSRTLFFADGERNKSIVVVIFDDETPEGDEKFQLILTNPSLGLELGENTTATITILANDDAHGVLSFNNSDHFFLREQTAIHLMESVAVLNIIREPPQGIFGTVTVQYLVSEINSSEPSVDLTPSQGYVVLEEGVRLKTLHISAILDEEPEMDEHFIVTLFNPTGGARLGTRVETMITVLQNQAPLGLFSIYPVSNRTNFLIVEEANTTAYLKVSRTNGLNTSVSIEWETQSNTAFGIRDGISVLSVLQSFVEELVSGWCFFTSGEILYGVLLHEPPATFSTVYQWKGVFIPVENFTVWNPKSCMSYQISGSSYLVVSHGGAGQGASDNSVYTFMPGRRLLWMQTLSVLDTRHVKHFAVEEEDYLIIVSHPTSSSSIQIFQWNKNTFLLHHQLPLYGVLNIDLFPRGGFMYMLVSLSNTSQNMLLYQWLNNEFRRLREVPEKEVKHMESWISGSDIYLITAKESGNSSEIFIWETGQSTFRHFQSLPMHDVRIIHVFMPPSGLVHILLAGKNVTALYSWNSEANSFSIMLEAPYADHITSVIARSLNSSKSLIVLSMESKSQIYELTTVSNQSDFIPSSGELIFDPGDMAVVIAVNILDDIIPEEEECFRVWLKNPKGGAEIGSHGFVDIIIPSNDNAYGVIAFAQNSLFKQVEEMEQDSLITLNIERLVGTYGRVTVEWIANGSISDVFPASGMITFSEGQALSTITLTILADSAAELSETVAITLTRVTTVGVQDTTRGATIDPKRSRAVLTILPSDSPHGVIGWHTNSLFVKVTEPEGEMNSTTVTLQIVREQGFVGEIAVQLSTEPNLDLPLSNQATENEDYIVEKKTIVMMDNATTASVMITILPDDVPELQEGFIINITDVQLIDSLARGQPSVKRIGLEIAEITIEENDDARGIFSFSVTKDKTGTVAGYEVPPPHNILKLPVVRQAGRFGSAVLYWEAILLTAGFEDFTPSSGNLTFTDGQATGEIEITIIDDSEVEFLEIFKIVLVRVTGGARLGDETLVTVAIPPNDSPVGVFGFEEKNITVKEPQTLDDSAAIALLTVSRSPGGQGAVKVIWILEEAAEHDLTPLNGTLHFNETESQKFIVIRAVEDGILEGNETFTIQLVSAGDAEISPVNGLATIIILGDEGASGVVGIAHSFKHVLIGEPSGNYNGTALISLTRGPGIFGEIIIYWNITPPHYTEFTEISGALTMKDRQSAAVVLIQALDDDHPEEKSYYQFQLTGISDGALINESSNIANITMAASDLPYGEFTFSRELFQTTEEERWVNITIVRSRGCYGKVRLWFQIINGTAEEGIDFTPTVRELLFEPDEENKMILIEIHDDDIPEGPEDFLVMITKVELQGSGFDFTIKENGLQVDQPPIIGNISTIRVTIAKSDNAEGIIEFDPQYLLLQVEEDAGVITIPVVRKRGTYGYVTADFLSRSISALPNGVDYVIHNNSVTFHHGQNQTFIYISIIDDEESEFAEQFEIQLTGATGGAVLGLHLVSQITIAKSDSPLGIVRFLNKSRIILPNPDTPTTVSLVLERTGRLLGDTQINWDILGPNSEEILSPLNSDIGDPVNGSFYFGEGEGGLRTIHLQIYPHEDIEVQEIFVIRLSLVKGETEIDPKSNNITLIIQKFGDPNGIVQFAPESLFERNFTEPSAVEGPQNITLFLRRVQGTLGNITVHWKLYSEFDITSDFLTTEGSVVIADQQSTGEIIIYLLPDDVPELDENYIVQLISVEGGADLDEDKRISKINVFANDDPHGVFALYSDHQSILVEKDLDRYVQINVTRHAGTFGEVVIEYHIFSHQEEELIAPENERGYFTIKDGASFAVKRVPISSQAFLLLDLNFTLELINVSLVRESAKYVPKILEKAKSAVVLVPAEAANSQVGFESVILQLTNIVAGTGQAVITRKGVYGSVTVNWISGYPPELTTDFVQPGNITPSFGIVLFSSGEQSKVITFRATPNINKRESFAISLTEVHSNVSGGAQLRSGFTIAEIEPMGIFQFAFNSTFISVEEDVESVTLHVQKLFGFRSNVTKLTYQTTPGSAKPLEDFRPIHNGELIFAHFQTNAMIEISIIDDTLSEIEEYFFVNLTAVEILDFQPAKLDWSPRLNPAFSVATINILANDILHGILSLGPEFIYVEEDANNNTPNTVIINIRRTQGFTGDIEVTIKTFGGISAQNGVGLYPFENVYGKSNFTWAMEGEDFEEQSVSLTLLDGERESKVSIKIFDDDEPEGQEFFYVFLSDPKHGAQIVKGKDEYGFAAFATVIIAGSDLQNGILGFIPEVQSGLILDEDSENREVLLVVARQPNRAFEDVKVFWRVTFNETSAVLLKDGVNLENELVSVLGVTTCMAGQTMCNISIEIKPDNVPEFETYFFVELYDVSAGAALNSSARFAFVTVLESDAPHGLVYFAVGSRFAVAHKKTTLISLQVLRDSSTSVTTKVSYNMQELQKPETVGRTFISPAVAGQDFARSEGLLTFEPGQRNKFLDVTLTPETASLNPFPKRFQVVLSNPTGGARVDDVYGVANVTIVSDLGSLPFWMLIDQLHQPLDDMILQRVLQNLNVKVATETTEEQLTAVMHVIDKVTDVGEKHLLTGKSRSLFYEILCALASPKRKDTRGYSLLAEVTEKFAFSLLTEIMCGSPGERGKNILDTCPYIAIMAHNWYPQQINGHRFDGRDGDSIQVPEHLLKVSLVLSPPQEENCESIQFTEYSSQQWFLTGDKELALKNKVFSMSLKSQSSHPLKDSNEVIYRIYATGSRIVPQKSLCLLWNQAAESWLSDSGFCRVIDDTSDYVECACSHMSIYAVYAQTDDLSSYNEAFFSSGFICISGFTLAIISHLFCTRCAMFAAKLLTHMMVACLGTQISFLASAYLSQHLSEESCSALASITHYLYLCQFSWMLIQVSLLVLFHPFPKTFKRTVTEIVSVFFLLLLFVCFVCVC", "length": 5954, "header": "tr|A0A8V0YK19-1|A0A8V0YK27_CHICK Computationally mapped isoform of Adhesion G-protein coupled receptor V1 OS=Gallus gallus OX=9031 GN=ADGRV1 PE=3 SV=1 CANONICAL=A0A8V0YK27-1" }, "locus": { "chromosome": "Z", "start_pos": 60491049, "end_pos": 60315557, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031207.1", "url": "https://www.ensembl.org/id/ENSGALT00010031207.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018182.1", "url": "https://www.ensembl.org/id/ENSGALP00010018182.1" } ] } }, { "isoform_ac": "A0A8V0YK27-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK27/entry#A0A8V0YK27-1", "sequence": { "sequence": "MSMSLGLGMHSDSLLVYLLLALVIHFTSGETEVKFSGQTEFVVNETSTTVIRLVIERTGKPANVTAIVSIHGEDTGDFFDTYAAAFIPDTETNRTVYISVCDDDLPEADETFTFYLTLPKQSAKIKLGSPKTVTVTILSNDNAFGIISFNMSALITVNEPRGRNEFVPLTLIRERGTYGIVIVTFEIKDGPNPAEEDFSPARGNITFTPGRSIVIYNLTVLDDQIPENDELFVVYLRSVEGGAEINTTKNSIQINIKKNDSPVRFIQSTYMVPEEVDILRIQVVRGKDDSGKLIGPDDCEVSVTYAIITGNSTSHAQLNLDFLDLQPNTTIVFPPLVHEIYMKFKILDDAIPEIAESFQIVLLKDTLQGDAVLVNPSTVHVTIQPNDKPYGVLSINSILFAQTVVIDEDKVSRFEGITIVRNGGTHGNVSVTWVIIRNSSDPSPVTVDLIPETGEIYFDQGQMLVTLPLNILNDDMPEEAEPYLLKLLAHTVQGGAEVSEPSELLFYIQDSDDVYGLIKFYPLENQKIQSNPTGRFLSLSFARERGTVGDVQLIYTALYIPAGDLDPDRAKDGILNISRNNILTFPEGKTHESLNIPIRNDAFLQNGAHFLIQLKGVELVNKIPLVPSVSPRLGEIRNISLRITPDIANGEIGFISNLPIILSEPEDSPATEVSIALHRDGTDGQATVFWSLKPSGVNQKAVTHDDISPFNGSVVFLSGQSDTTINITVKADDIPEMNETVLLTLDRVSVENQILKYGFTTREIIILENDDPGGVFEFSSSSRGPYSIKEGESVELQIVRARGSLVRQFLRYTVEPRDNNEFYGSTGILEFKPGEREIIITLLTRMDGIPELDEIYSVVLSSHSEMPGKLGNATMVNITILKNDDPHGIIEFLPDELTVTINESKGEDIYTAVYRVIRNQGNYGNVNVSWVVDPACTNDVYPEGGTIFFDNLEFSKNITIYSLPDEVPEEREVFLISLFSVTGGARLGNVTTAILQITGNDDPIYFAEPLTVTVQEGSVANFTVLRNGSADVAVAVHYITVNGDATAEEGDFVPSGKSSIIWFDIGEREQNLSVYINDDDIPETDETFYVLLLNSTGDTVIFKAGMATVIIEANDDSNGIFSLEPLEKAVEEGKSNTFLILRHRGHFGNVSLSWQLFDNNSALQPGEEFYETYGTVFFMDGERSKPVTLHAISDRIPEFNEFYILKLVNASGGSPGPGGQLSETNLSVIIMIPFNDDPFGVFVIDPDSQEREIVEDTLSEDDLSYITDFTIWRQQGTFGVVRLGWEILSSMFPDGLPAMIDFLLLGSFTSSVKSQPHMRRHHSGTDALYFSGKEDAFGIIGPEDPYNGNTALTSFTFSAWLIPDVRTDGYIVEKDNDNGTLYYGVKIQTNDSHVCVVLHYTAIGSYMTYMAKTAVMKYLDENTWLHLLITLDESIIEFYIDGILVLGGMKSLKGEAIVDGPGIVRIGAGINGSSRYIGLMQDVRLYERKLTHAEIYELHATPAKNDVHPVSGYLEYRQGETNKSFIVSAKDDNEEEGEELFILKLICVRGGARISQENATARLRIQKSDNANGLFGFTGSCIPETSDEGSTISCVVERTRGALDYVYIKYIISQVDSTGINYSVTDFSNSSGTITFLPWQRSEVLNLHVIDDDIPELNEYFRVTLVSAVSGDGKLGSTPTSGASIDPEKETTDISIRASDHPYGLLQFSVGLPPQPGDKMILPASSVPHITIKEEVGHIRLLVVRAQGLLGTVLVEYRTVPLTAFSPKDYQAVMGTLEFQPGERYKYITVNITDNSIPELEKTFEVELLNPGGGVAELFRNDGSGSGDGNMDFFLQTAYQHASLGIASHIIVTIEASDDAHGVFEFSAESLSVNGTEPEDGDSNIVLQIVRTHGALSEVTLHWIVDCDVSEDLISTYGNITFDVGQVRANITVQVSPDDIPELDKMFSVLIINVSSGRLGNHTNATLTVLANDDPYGLFIFSEKNRPIKVEEETKNISLTIIRLGGLLGTVVVTYRTLGDDEKPSFLPPNVVRAIQGKDYIPITGYTVFAANEREATISLPILDDDDPERSESVFVELNNTVLIEKVQDRPIVNSPRLGSASETIAHVIINANDDAFGTLQLSASTVRVAENYVGPIINVTRTGGIFADVSVKFKAMPITATAGEDYSVASSDVVLLEGETSKAVPIYIINDINPEIEESFYVQLLNQTTGGALLGSLTRAIIIIEASDDPFGSFVFQITEFTVEEPEFGSVPIDLPVIRNAGTLGNVTVHWIATIDGHLAHADLQFATGNITFAPGETFQMLLLEILADDVPEIDEVVLVVLTQASNGGAIGVDGMAKITIPANDNPYGTVFFHQSLYRIQEPLERNLLANITVRRSEGRFGQLQIFYSTSETDIVALAVEQGQDILAYYESPVQGIPDQPSKTRVNVSAASDPVYVCATQCLKEQACSAFTFSNTSGIPLCLWLTSEISPLTNTSGFWTYKKNCTSAFTLLSTQAIAGSDYQPVTRQWAIMEEGEEFANLTVIILPDDLPELDEKFTITLLKVELMNISASLKNQPTIGQPNTSTVIIMMNGDAFGVFKIYSVSPNASEKGLYVEVEERPQASVQLMIHRTEGSLGQVTVQWHVTGGTATPNVDFIGVGETLVFAEGETKKMAVLTILDDPEPEDNESIKISLIHTEGGSRILPSFDTVTVIILASDNVAGIISFHTASRSVIGREGEQLQFHIVRTAPGLGNVTVEWKIVGHNVKQNFETYSGILFFAEGMLNTTLYIHLLDDHIPEEKEEYQIILYNIKTEGVSPTGAAVLDSQGYEAVLTVEASDEPHGVLNFASTSRVVLSPEENKTIQLFINREFGSLGTINVTYATVTGLLSVSNQTEPTLAEPGDDYIPTSGSLILEEGETSAAINITILEDDIPEVQEFFLVNLTSVELIMNHSISSPPRLDVEGLASQIIIDANDGVRGVIEWEGTNFEVSESHGNLTIMAYRNRGSYGNVSVFFYAQNLEAQLGLDFYVTSRTLFFADGERNKSIVVVIFDDETPEGDEKFQLILTNPSLGLELGENTTATITILANDDAHGVLSFNNSDHFFLREQTAIHLMESVAVLNIIREPPQGIFGTVTVQYLVSEINSSEPSVDLTPSQGYVVLEEGVRLKTLHISAILDEEPEMDEHFIVTLFNPTGGARLGTRVETMITVLQNQAPLGLFSIYPVSNRTNFLIVEEANTTAYLKVSRTNGLNTSVSIEWETQSNTAFGIRDGISVLSVLQSFVEELVSGWCFFTSGEILYGVLLHEPPATFSTVYQWKGVFIPVENFTVWNPKSCMSYQISGSSYLVVSHGGAGQGASDNSVYTFMPGRRLLWMQTLSVLDTRHVKHFAVEEEDYLIIVSHPTSSSSIQIFQWNKNTFLLHHQLPLYGVLNIDLFPRGGFMYMLVSLSNTSQNMLLYQWLNNEFRRLREVPEKEVKHMESWISGSDIYLITAKESGNSSEIFIWETGQSTFRHFQSLPMHDVRIIHVFMPPSGLVHILLAGKNVTALYSWNSEANSFSIMLEAPYADHITSVIARSLNSSKSLIVLSMESKSQIYELTTVSNQSDFIPSSGELIFDPGDMAVVIAVNILDDIIPEEEECFRVWLKNPKGGAEIGSHGFVDIIIPSNDNAYGVIAFAQNSLFKQVEEMEQDSLITLNIERLVGTYGRVTVEWIANGSISDVFPASGMITFSEGQALSTITLTILADSAAELSETVAITLTRVTTVGVQDTTRGATIDPKRSRAVLTILPSDSPHGVIGWHTNSLFVKVTEPEGEMNSTTVTLQIVREQGFVGEIAVQLSTEPNLDLPLSNQATENEDYIVEKKTIVMMDNATTASVMITILPDDVPELQEGFIINITDVQLIDSLARGQPSVKRIGLEIAEITIEENDDARGIFSFSVTKDKTGTVAGYEVPPPHNILKLPVVRQAGRFGSAVLYWEAILLTAGFEDFTPSSGNLTFTDGQATGEIEITIIDDSEVEFLEIFKIVLVRVTGGARLGDETLVTVAIPPNDSPVGVFGFEEKNITVKEPQTLDDSAAIALLTVSRSPGGQGAVKVIWILEEAAEHDLTPLNGTLHFNETESQKFIVIRAVEDGILEGNETFTIQLVSAGDAEISPVNGLATIIILGDEGASGVVGIAHSFKHVLIGEPSGNYNGTALISLTRGPGIFGEIIIYWNITPPHYTEFTEISGALTMKDRQSAAVVLIQALDDDHPEEKSYYQFQLTGISDGALINESSNIANITMAASDLPYGEFTFSRELFQTTEEERWVNITIVRSRGCYGKVRLWFQIINGTAEEGIDFTPTVRELLFEPDEENKMILIEIHDDDIPEGPEDFLVMITKVELQGSGFDFTIKENGLQVDQPPIIGNISTIRVTIAKSDNAEGIIEFDPQYLLLQVEEDAGVITIPVVRKRGTYGYVTADFLSRSISALPNGVDYVIHNNSVTFHHGQNQTFIYISIIDDEESEFAEQFEIQLTGATGGAVLGLHLVSQITIAKSDSPLGIVRFLNKSRIILPNPDTPTTVSLVLERTGRLLGDTQINWDILGPNSEEILSPLNSDIGDPVNGSFYFGEGEGGLRTIHLQIYPHEDIEVQEIFVIRLSLVKGETEIDPKSNNITLIIQKFGDPNGIVQFAPESLFERNFTEPSAVEGPQNITLFLRRVQGTLGNITVHWKLYSEFDITSDFLTTEGSVVIADQQSTGEIIIYLLPDDVPELDENYIVQLISVEGGADLDEDKRISKINVFANDDPHGVFALYSDHQSILVEKDLDRYVQINVTRHAGTFGEVVIEYHIFSHQEEELIAPENERGYFTIKDGASFAVKRVPISSQAFLLLDLNFTLELINVSLVRESAKYVPKILEKAKSAVVLVPAEAANSQVGFESVILQLTNIVAGTGQAVITRKGVYGSVTVNWISGYPPELTTDFVQPGNITPSFGIVLFSSGEQSKVITFRATPNINKRESFAISLTEVHSNVSGGAQLRSGFTIAEIEPMGIFQFAFNSTFISVEEDVESVTLHVQKLFGFRSNVTKLTYQTTPGSAKPLEDFRPIHNGELIFAHFQTNAMIEISIIDDTLSEIEEYFFVNLTAVEILDFQPAKLDWSPRLNPAFSVATINILANDILHGILSLGPEFIYVEEDANNNTPNTVIINIRRTQGFTGDIEVTIKTFGGISAQNGVGLYPFENVYGKSNFTWAMEGEDFEEQSVSLTLLDGERESKVSIKIFDDDEPEGQEFFYVFLSDPKHGAQIVKGKDEYGFAAFATVIIAGSDLQNGILGFIPEVQSGLILDEDSENREVLLVVARQPNRAFEDVKVFWRVTFNETSAVLLKDGVNLENELVSVLGVTTCMAGQTMCNISIEIKPDNVPEFETYFFVELYDVSAGAALNSSARFAFVTVLESDAPHGLVYFAVGSRFAVAHKKTTLISLQVLRDSSTSVTTKVSYNMQELQKPETVGRTFISPAVAGQDFARSEGLLTFEPGQRNKFLDVTLTPETASLNPFPKRFQVVLSNPTGGARVDDVYGVANVTIVSDLGSLPFWMLIDQLHQPLDDMILQRVLQNLNVKVATETTEEQLTAVMHVIDKVTDVGEKHLLTGKSRSLFYEILCALASPKRKDTRGYSLLAEVTEKFAFSLLTEIMCGSPGERGKNILDTCPYIAIMAHNWYPQQINGHRFDGRDGDSIQVPEHLLKVSLVLSPPQEENCESIQFTEYSSQQWFLTGDKELALKNKVFSMSLKSQSSHPLKDSNEVIYRIYATGSRIVPQKSLCLLWNQAAESWLSDSGFCRVIDDTSDYVECACSHMSIYAVYAQTDDLSSYNEAFFSSGFICISGFTLAIISHLFCTRCAMFAAKLLTHMMVACLGTQISFLASAYLSQHLSEESCSALASITHYLYLCQFSWMLIQAVNFWYVLVMNDEHTERRYLLYFLLSWGLPAFIVILLLIILRGIYHHSTAQIYGLVYSDLCFIPNAYAALFTAALMPLMCLVVVFVVFVHAYQVTPQWKAYDDIFRGRTNAAEIPLVLYLFALISITWLWGGLHMAYRHLWMLVFFIIFNSLQGLYVFVVYFILHNQLCCPVKASYTVDMNGHSTPGSAFFTHGSGLPAAGGEISKSTQNLISAMEEVPADWERASLQPASQASSAFKQSPQNGNVFHPSGGFSNSSLVADEESQEFDDLIFALKTGAGLSVSDNESCHGSQDGGSMANSQIVELRRIPIADTHL", "length": 6220, "header": "tr|A0A8V0YK27-1|A0A8V0YK27_CHICK Isoform 1 of Adhesion G-protein coupled receptor V1 OS=Gallus gallus OX=9031 GN=ADGRV1 PE=3 SV=1 CANONICAL=A0A8V0YK27-1" }, "locus": { "chromosome": "Z", "start_pos": 60491049, "end_pos": 60230802, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031214.1", "url": "https://www.ensembl.org/id/ENSGALT00010031214.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018187.1", "url": "https://www.ensembl.org/id/ENSGALP00010018187.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1680, "start_aa": "Thr", "end_pos": 1680, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1680", "evidence": [ { "id": 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[ "Protein Classification" ] }, { "id": "IPR012337", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012337", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036397", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036397", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PF00075", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00075", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YK31", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK31", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YK31-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK31-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLYLYTDSWMVANALWGWLQQWEQNNWQRRGKPVSAAELWKDIAAQIKNMVVKVHHVDAHVPKSWTTEEQQNNHLLDRAAKIEVAQIDLDWQNKSELFLARWAHETSGHQGRDATYKWARDRGVDLTMDAIAQVIHDCEMCAIIQQAKRMKPLWEEGRWQKYKYGEAW", "length": 168, "header": "tr|A0A8V0YK31-1|A0A8V0YK31_CHICK Isoform 1 of RNase H type-1 domain-containing protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0YK31-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YK31-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK31/entry#A0A8V0YK31-1", "sequence": { "sequence": "MLYLYTDSWMVANALWGWLQQWEQNNWQRRGKPVSAAELWKDIAAQIKNMVVKVHHVDAHVPKSWTTEEQQNNHLLDRAAKIEVAQIDLDWQNKSELFLARWAHETSGHQGRDATYKWARDRGVDLTMDAIAQVIHDCEMCAIIQQAKRMKPLWEEGRWQKYKYGEAW", "length": 168, "header": "tr|A0A8V0YK31-1|A0A8V0YK31_CHICK Isoform 1 of RNase H type-1 domain-containing protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0YK31-1" }, "locus": { "chromosome": "W", "start_pos": 2769713, "end_pos": 2769210, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028590.1", "url": "https://www.ensembl.org/id/ENSGALT00010028590.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016419.1", "url": "https://www.ensembl.org/id/ENSGALP00010016419.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "nucleic acid binding", "id": "GO:0003676", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003676", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YK31", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK31" } ], "pmid": "" }, { "name": "RNA-DNA hybrid ribonuclease activity", "id": "GO:0004523", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004523", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YK31", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK31" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 93, "end_pos": 95, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YK31", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK31" }, { "id": "PS50879", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50879" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RNase H type-1", "eco_id": "ECO_0000259", "start_pos": 1, "end_pos": 85, "start_aa": "Met", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 93, "end_pos": 95 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YLZ2-1", "uniprot_ac": "A0A8V0YLZ2", "uniprot_id": "A0A8V0YLZ2_CHICK", "mass": { "chemical_mass": 125038.0, "monoisotopic_mass": 125038.0 }, "refseq": { "ac": "XP_004940836", "name": "APC membrane recruitment protein 1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004940836" }, "gene_names": [ { "name": "AMER1", "type": "recommended", "evidence": [ { "id": "A0A8V0YLZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLZ2" } ] }, { "name": "AMER1", "type": "synonym", "evidence": [ { "id": "XP_004940836", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004940836" } ] } ], "protein_names": [ { "name": "APC membrane recruitment protein 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_004940836", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004940836" } ] }, { "name": "APC membrane recruitment protein 1", "type": "synonym", "evidence": [ { "id": "A0A8V0YLZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLZ2/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052535.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_004940836.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004940836", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004940836" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLZ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLZ2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "AMER1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLZ2", "locus": { "chromosome": "4", "start_pos": 11636868, "end_pos": 11619119, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013356", "url": "https://www.ensembl.org/id/ENSGALG00010013356" } ] } } ], "crossref": [ { "id": "A0A8V0YLZ2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YLZ2", "database": "AlphaFoldDB", "categories": [] }, { "id": "422314", "url": "https://www.ncbi.nlm.nih.gov/gene/422314", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR019003", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019003", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:422314", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422314", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WRDFPGT", "url": "https://omabrowser.org/oma/group/WRDFPGT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YK33", "url": "https://www.orthodb.org/?gene=A0A8V0YK33", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YLZ2", "url": "https://www.orthodb.org/?gene=A0A8V0YLZ2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YRX0", "url": "https://www.orthodb.org/?gene=A0A8V0YRX0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22237", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22237", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22237:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22237:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF09422", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09422", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-195253", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-195253", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-196299", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-196299", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_004940836", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004940836", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YK33", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK33", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YK33-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK33-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLZ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLZ2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLZ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLZ2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YRX0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRX0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YRX0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRX0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "METGCTEEAARTQSQSAACRQCKGGEQQPEENVERLSQRSDASATAAEQQQPQAPSGKLKKTAFKLFGGKRSICTLPSFFSSRNKGQGKGASKKGLSKSKTHDGISGTAYDEGSGVQLESPSDGSRDSHPCLLPSSQSVHVAIDTSVKFDFGRQDGSPPGSIEGYEKKPNGDKSSFPRPKKGLKGLLNSIRRHRKSKVAECEKTELSEWPGDSEETSKAQGTKAETPGAVEEGGPGSVPLAAACPGSSEDNCLVRTVADFGEAAEPDWLQADKGSCEGDVVAVPGGKDDLDAKSEVDAVVYTESNYSHLPVALHPDLADNDPPSLHSGDQLSLLFGDVTSLKSFDSLTGCGDIIAEPDILSIAESTISVERSRDTAKRSPCLVTYQGGGEEMAMSEEEYLQQIWDSTAEEGRSYEAPLPPVVSSPELQAVSSKLETCGLHEGEVHPYASGAVDGVEILTPQSDQQESAPNSDEGYYDSTTPGPEDETGDGLCEIKKDRLPRDSYSGDALYEFYEPDDTLMSPSHGEQSLFESKVSHPEIFSYFLDFCLPPEKSLIQMMDQKRGVMETEEERLAAIQKELLFWELQREPGLKRLDVPSKEKCPREKQHVECNTRAANLIGKSQSCLGSEQIASQALNRSVNGGILVARAENPEWSDFPGPLCPENCYNSQKAQGSCLIQLMKNNPGFDSDPDCALFGGSLHGSAALAKPGMFPSRRPLEHEGCLQSEHHSGVEAAGREPQADSECEPEHAMSFSQALVEFTSSGTLFSSLSESLGSSDSGSSFTQNLPVLPTMVTFDIVDVEQEGEGECEQHLEMNADEDMAASFEAFDESYVQKESFAECDERMFLGYPQGSFQSCNWGVASLPRHLHLHGLSPAMPAPLSLNRRSRSLDTESLEFELADLQVSKNGLKPCQLWSKWDKKYSDGARRSRSKEEAELSAPEGGETNGVLSWPGLQHLQYDAELAPGGIKHWGFAPAAGMPSSWEPSERSDADPPFFPLSRSCARETLERQPQDPEPNRLLVRPSNLPLQPDTRQPQEASGSYRYHGEAPAKKLARVLPLGEPEPPQSISFAQSPEKPAKCKPVGVTQGMPQCHDSDDTETLKSSACFAERYGSASKELLKARAAPGNVLPSGCLNTAVNCDPPLSNTIHDAKCGSSPSA", "length": 1158, "header": "tr|A0A8V0YLZ2-1|A0A8V0YLZ2_CHICK Isoform 1 of APC membrane recruitment protein 1 OS=Gallus gallus OX=9031 GN=AMER1 PE=3 SV=1 CANONICAL=A0A8V0YLZ2-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YK33-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLZ2/entry#A0A8V0YK33-1", "sequence": { "sequence": "METGCTEEAARTQSQSAACRQCKGGEQQPEENVERLSQRSDASATAAEQQQPQAPSGKLKKTAFKLFGGKRSICTLPSFFSSRNKGQGKGASKKGLSKSKTHDGISGTAYDEGSGVQLESPSDGSRDSHPCLLPSSQSVHVAIDTSVKFDFGRQDGSPPGSIEGYEKKPNGDKSSFPRPKKGLKGLLNSIRRHRKSKVAECEKTELSEWPGDSEETSKAQGTKAETPGAVEEGGPGSVPLAAACPGSSEDNCLVRTVADFGEAAEPDWLQADKGSCEGDVVAVPGGKDDLDAKSEVDAVVYTESNYSHLPVALHPDLADNDPPSLHSGDQLSLLFGDVTSLKSFDSLTGCGDIIAEPDILSIAESTISVERSRDTAKRSPCLVTYQGGGEEMAMSEEEYLQQIWDSTAEEGRSYEAPLPPVVSSPELQAVSSKLETCGLHEGEVHPYASGAVDGVEILTPQSDQQESAPNSDEGYYDSTTPGPEDETGDGLCEIKKDRLPRDSYSGDALYEFYEPDDTLMSPSHGEQSLFESKVSHPEIFSYFLDFCLPPEKSLIQMMDQKRGVMETEEERLAAIQKELLFWELQREPGLKRLDVPSKEKCPREKQHVECNTRAANLIGKSQSCLGSEQIASQALNRSVNGGILVARAENPEWSDFPGPLCPENCYNSQKAQGSCLIQLMKNNPGFDSDPDCALFGGSLHGSAALAKPGMFPSRRPLEHEGCLQSEHHSGVEAAGREPQADSECEPEHAMSFSQALVEFTSSGTLFSSLSESLGSSDSGSSFTQNLPVLPTMVTFDIVDVEQEGEGECEQHLEMNADEDMAASFEAFDESYVQKESFAECDERMFLGYPQGSFQSCNWGVASLPRHLHLHGLSPAMPAPLSLNRRSRSLDTESLEFELADLQVSKNGLKPCQLWSKWDKKYSDGARRSRSKEEAELSAPEGGETNGVLSWPGLQHLQYDAELAPGGIKHWGFAPAAGMPSSWEPSERSDADPPFFPLSRSCARETLERQPQDPEPNRLLVRPSNLPLQPDTRQPQEASGSYRYHGEAPAKKLARVLPLGEPEPPQSISFAQSPEKPAKCKPVGVTQGMPQCHDSDDTETLKSSACFAERYGSASKELLKARAAPGNVLPSGCLNTAVNVMGAK", "length": 1143, "header": "tr|A0A8V0YK33-1|A0A8V0YLZ2_CHICK Computationally mapped isoform of APC membrane recruitment protein 1 OS=Gallus gallus OX=9031 GN=AMER1 PE=3 SV=1 CANONICAL=A0A8V0YLZ2-1" }, "locus": { "chromosome": "4", "start_pos": 11631629, "end_pos": 11630632, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032149.1", "url": "https://www.ensembl.org/id/ENSGALT00010032149.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018939.1", "url": "https://www.ensembl.org/id/ENSGALP00010018939.1" } ] } }, { "isoform_ac": "A0A8V0YLZ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLZ2/entry#A0A8V0YLZ2-1", "sequence": { "sequence": "METGCTEEAARTQSQSAACRQCKGGEQQPEENVERLSQRSDASATAAEQQQPQAPSGKLKKTAFKLFGGKRSICTLPSFFSSRNKGQGKGASKKGLSKSKTHDGISGTAYDEGSGVQLESPSDGSRDSHPCLLPSSQSVHVAIDTSVKFDFGRQDGSPPGSIEGYEKKPNGDKSSFPRPKKGLKGLLNSIRRHRKSKVAECEKTELSEWPGDSEETSKAQGTKAETPGAVEEGGPGSVPLAAACPGSSEDNCLVRTVADFGEAAEPDWLQADKGSCEGDVVAVPGGKDDLDAKSEVDAVVYTESNYSHLPVALHPDLADNDPPSLHSGDQLSLLFGDVTSLKSFDSLTGCGDIIAEPDILSIAESTISVERSRDTAKRSPCLVTYQGGGEEMAMSEEEYLQQIWDSTAEEGRSYEAPLPPVVSSPELQAVSSKLETCGLHEGEVHPYASGAVDGVEILTPQSDQQESAPNSDEGYYDSTTPGPEDETGDGLCEIKKDRLPRDSYSGDALYEFYEPDDTLMSPSHGEQSLFESKVSHPEIFSYFLDFCLPPEKSLIQMMDQKRGVMETEEERLAAIQKELLFWELQREPGLKRLDVPSKEKCPREKQHVECNTRAANLIGKSQSCLGSEQIASQALNRSVNGGILVARAENPEWSDFPGPLCPENCYNSQKAQGSCLIQLMKNNPGFDSDPDCALFGGSLHGSAALAKPGMFPSRRPLEHEGCLQSEHHSGVEAAGREPQADSECEPEHAMSFSQALVEFTSSGTLFSSLSESLGSSDSGSSFTQNLPVLPTMVTFDIVDVEQEGEGECEQHLEMNADEDMAASFEAFDESYVQKESFAECDERMFLGYPQGSFQSCNWGVASLPRHLHLHGLSPAMPAPLSLNRRSRSLDTESLEFELADLQVSKNGLKPCQLWSKWDKKYSDGARRSRSKEEAELSAPEGGETNGVLSWPGLQHLQYDAELAPGGIKHWGFAPAAGMPSSWEPSERSDADPPFFPLSRSCARETLERQPQDPEPNRLLVRPSNLPLQPDTRQPQEASGSYRYHGEAPAKKLARVLPLGEPEPPQSISFAQSPEKPAKCKPVGVTQGMPQCHDSDDTETLKSSACFAERYGSASKELLKARAAPGNVLPSGCLNTAVNCDPPLSNTIHDAKCGSSPSA", "length": 1158, "header": "tr|A0A8V0YLZ2-1|A0A8V0YLZ2_CHICK Isoform 1 of APC membrane recruitment protein 1 OS=Gallus gallus OX=9031 GN=AMER1 PE=3 SV=1 CANONICAL=A0A8V0YLZ2-1" }, "locus": { "chromosome": "4", "start_pos": 11630603, "end_pos": 11626870, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032143.1", "url": "https://www.ensembl.org/id/ENSGALT00010032143.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018933.1", "url": "https://www.ensembl.org/id/ENSGALP00010018933.1" } ] } }, { "isoform_ac": "A0A8V0YRX0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLZ2/entry#A0A8V0YRX0-1", "sequence": { "sequence": "METGCTEEAARTQSQSAACRQCKGGEQQPEENVERLSQRSDASATAAEQQQPQAPSGKLKKTAFKLFGGKRSICTLPSFFSSRNKGQGKGASKKGLSKSKTHDGISGTAYDEGSGVQLESPSDGSRDSHPCLLPSSQSVHVAIDTSVKFDFGRQDGSPPGSIEGYEKKPNGDKSSFPRPKKGLKGLLNSIRRHRKSKVAECEKTELSEWPGDSEETSKAQGTKAETPGAVEEGGPGSVPLAAACPGSSEDNCLVRTVADFGEAAEPDWLQADKGSCEGDVVAVPGGKDDLDAKSEVDAVVYTESNYSHLPVALHPDLADNDPPSLHSGDQLSLLFGDVTSLKSFDSLTGCGDIIAEPDILSIAESTISVERSRDTAKRSPCLVTYQGGGEEMAMSEEEYLQQIWDSTAEEGRSYEAPLPPVVSSPELQAVSSKLETCGLHEGEVHPYASGAVDGVEILTPQSDQQESAPNSDEGYYDSTTPGPEDETGDGLCEIKKDRLPRDSYSGDALYEFYEPDDTLMSPSHGEQSLFESKVSHPEIFSYFLDFCLPPEKSLIQMMDQKRGVMETEEERLAAIQKELLFWELQREPGLKRLDVPSKEKCPREKQHVECNTRAANLIGKSQSCLGSEQIASQALNRSVNGGILVARAENPEWSDFPGPLCPENCYNSQKAQGSCLIQLMKNNPGFDSDPDCALFGGSLHGSAALAKPGMFPSRRPLEHEGCLQSEHHSGVEAAGREPQADSECEPEHAMSFSQALVEFTSSGTLFSSLSESLGSSDSGSSFTQNLPVLPTMVTFDIVDVEQEGEGECEQHLEMNADEDMAASFEAFDESYVQKESFAECDERMFLGYPQGSFQSCNWGVASLPRHLHLHGLSPAMPAPLSLNRRSRSLDTESLEFELADLQVSKNGLKPCQLWSKWDKKYSDGARRSRSKEEAELSAPEGGETNGVLSWPGLQHLQYDAELAPGGIKHWGFAPAAGMPSSWEPSERSDADPPFFPLSRSCARETLERQPQDPEPNRLLVRPSNLPLQPDTRQPQEASGSYRYHGEAPAKKLARVLPLGEPEPPQSISFAQSPEKPAKCKPVGVTQGMPQCHDSDDTETLKSSACFAERYGSASKELLKARAAPGNVLPSGCLNTAVNVRSGKTYWTTVPRL", "length": 1152, "header": "tr|A0A8V0YRX0-1|A0A8V0YRX0_CHICK Computationally mapped isoform of APC membrane recruitment protein 1 OS=Gallus gallus OX=9031 GN=AMER1 PE=3 SV=1 CANONICAL=A0A8V0YLZ2-1" }, "locus": { "chromosome": "4", "start_pos": 11633756, "end_pos": 11626870, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032146.1", "url": "https://www.ensembl.org/id/ENSGALT00010032146.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018936.1", "url": "https://www.ensembl.org/id/ENSGALP00010018936.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:422314", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422314", "resource": "KEGG Pathway" }, { "id": "R-GGA-195253", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-195253", "resource": "Reactome", "description": "Degradation of beta-catenin by the destruction complex" }, { "id": "R-GGA-196299", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-196299", "resource": "Reactome", "description": "Beta-catenin phosphorylation cascade" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A5K1UCI1-1", "protein_name": "APC membrane recruitment protein 1", "gene_name": "AMER1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "METRKDESPQAKGAAVSVDTQDQGAENGAKNKAAEMIEGPASEPPSSGPGRLKKTAMKLFGGKKGICTLPSFFGGGRSKCSGKGNSKKGLSKSKTHDGLSEADHGLEDIVSEGTGLSLPLPESSCQLLSSQSAHGSLEIGSRCKISVAGTTEKVPFVTKPKKGLKGFFSSIRRHRKSKVSGAEQSDPGAKEPEGARARLYEHVSSALLPHTEQTLQAPREENTKSQDPPGPKVSSLSEPSPTATEKTACKDPEKNTKACASALLQPKPALEASSPEEPHSPETGEKVVAEEVNPPGGPVGDQLSLLFGDVTSLKSFDSLTGCGDIIAEQDMDSMTDSMASGGQRANRDGTKRSSCLVTYQGGGEEMALPDDDDEEEEEVELEEEEEEVKEEEDDDLEYMRASAQVYPRPNLNPGYHSTTSPGHHGYMLLDPVRSYPGLAPGDLLTPQSDQQESAPNSDEGYYDSTTPGLEDDSGEALGLVHRDCLPRDSYSGDALYEFYEPDDSLENSPPGDDCLYDLHGHSSEMFDPFLNFDPFSSSRPPGAMETEEERLVTIQKQLLYWELRREQLEAQEAHAREAHAREAYTQETHTREAHAQEAYAREACVREVRAREAQVREVQARQEKPIMEYQKRPLGPSVMGLVEGASGASQTSHKGTTSAFPATESSQPDWRDFRPLEKRFEGTCSKKDQSACLMQLFQSDAMFEPDMQEANFGGSPRRAYPTYSPPEEPEEEEVEKEGNATVSFSQALVEFTSNGNLFSSMSCSSDSDSSFTQNLPELPPMVTFDIADVERDGEGKCEENLEFHNDEDLAASLEAYELGYYQKHAFNNYCSRFYQGLPWGVSSLPRYLGLPGMHPRPPPAAMALNRRSRSLDTAETLELELSNSHLAQGYMESDELHAQQEDSDEEEEEEWGRDSPLSLYTEPPGTYDWPAWAPCPLPVRLGPAWISPSQLDGPSSQSQHGKTACCVSPVAMSMLLSVSGPEPKAPGESKAQLARPSHLPLPMGPCYNLQPKVSQSARARPRDMLLPVDEPSCSFSSGGFSPSPLPQAKPVGITHGIPQLPRVRPEPPEPQSIHCGASTLDLSKERAEEGASLPTIYSSTAMDGNLAE", "length": 1108 }, "evidence": [ { "id": "A0A8V0YLZ2", "url": "https://omabrowser.org/oma/group/A0A8V0YLZ2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "D3ZCP6-1", "protein_name": "APC membrane recruitment protein 1", "gene_name": "Amer1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEIQQDETVQIKRTSTSSDAQDQGAEKGAKNKTAETTEGSTSEPPLSGPGRLKKTALKLFGGKKGICTLPSFFGGGRSKGSGKGSSKKGLNKSKTHDGLSESSHGPEDVVVEETELSTPLSKSPSQFPSSQSAHGALEIGSRHKTSVTEAVEKAGVEKVPSVHKPKKGLKGFLNSIRRHRKSKVSGADQSGLGAKELEGTRTMSQEHVSSISLPSSEEIFRDAIKENTKPQDAPGPKMSPAREHFSLTTEKTACKNPEKLTMTCASEFMQPKPILEASSLEEPHTSETEGKVVTGDANPPNGPVGDQLSLLFGDVTSLKSFDSLTGCGDIIAEQDMDSMTDSMASGGQRANRDGTKRSSCLVTYQGGGEEMALPDDDDNEEEEEEDEEVELEDEEEEVKDGEEDDDLEYLWASAQIYPRFNMNLGYHTAISPSHQGYMLLDPVQSYPNLGLGELLTPQSDQQESAPNSDEGYYDSTTPGFEDDSGEALGLVHRDCLPRDSYSGDALYEFYEPDDSLEHSPPGDDCLYDLRGRNSEMLDPFLNLEPFSSRPPGAMETEEERLVTIQKQLLYWELRREQREAQEACAREAHAREAYSRDTHTRESYGKNTRARETQALEVHSQEGRVQETKVRQEKPALEYQMRPLGPSVMGLVPGTPGGSQTSHRGTTSAFPATSSSEPDWRDFRPLEKRFEGTCSKKDQSTCLMQLFQSDAMFEPDMQEANFGGSPRKAYPSYSPPEEPEEEEDENEGNATVSFSQALVEFTSNGNLFTSMSYSSDSDSSFTQNLPELPPMVTFDIADVERDGEGKCEENPEFNNDEDLTASLEAFELGYYHKHAFNSYHSRFYQGLPWGVSSLPRYLGLPGVHPRPPPAAMALNRRSRSLDNAETLELELSSSHLAQGYVESDELQDHQEDSDEEGEEEEGEWGRDSPLSLYTEPPGVYDWPPWAHCPVPVGPGLAWLSPNQLDEPFNQSSYVQATCCVPPVAMSVPGRAPGDSVSQPARPSHLPLPMGPCYNLQSQASQSGRARPRDVLLPVDEPSCSSISGANSLSQAKPVGITHGIPQLPRVRPEPLQLQPNHYRASNLDLSKERGEQGASLSTSYSSTAMNGNLAK", "length": 1111 }, "evidence": [ { "id": "A0A8V0YLZ2", "url": "https://omabrowser.org/oma/group/A0A8V0YLZ2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1RDM5-1", "protein_name": "APC membrane recruitment protein 1", "gene_name": "amer1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEIATRCEVGAMRGPSSDSVSHDIPQPQSPPSVKIRKTAFKFFGGRKSICVLPSFFGGRGRSQRKGSSKTGVTKSQTYDGVSRACWDDLGRSSSEVASGDFEFCSEPQKSQEDHGKSQSLPRQRRGLRGLFSSIRRHRKNKNVEVEKREALEMSSSFHAKTVPGALPSVSDRGDYHGDSQGEELVPDVPNQTTGSECELPLAATECTIDVTLVPEKRRSRVEMDKRRRAEEEGIGEDEKTGRQEGLMTYHQPLSAESELDRLAEQNVDVPDGEPPVASCSSENLVFGDVSSLKSFDSLTGCGDIIADQDDVSVAESSVSADRGSRNAGKRSSCFVTYQGGGEEMATPDEIDADYLQSLWESETSNEVCYIPSDRGSDSPSLTPDQQLSSIRATSSSSPMGITETALTPADLLSPQSDRQESVPNSDEGYYDSTTPGMEEESRERPHQERLPRDSYSGDALYELFEPDDRLLSPSLPPKDAHSFVGAPLQADKSPTNPLYSLASTAIETGAMETEEERLSKIQHALLCCELQNLRSPSKNQLLFHSDCFYDDSNLPVDDSKQDLQEVINQRYPQSPPRSQAVKEGVPRIRGQVQESSLFAPCADSVLNPQVIETTRPQPQSDDQGSLRPSRGCSQSQEELMVCFSQALVDFTKNTRLYRNSTESLDGSESSSPFGPSLRALPAIVTFDVVDMENEGECEQQTDLAEEEEELASPYEPFEDDGCYLQQDAFAECDQRTFDAYEQSLLLSNAWGIASLPRHLSLGRPCPPVPAPLALNRRSRSLDTDSLEFQTSEIYTSVTKYDSKGTAFSQSRTVDCNDMDFPRQPCRITVDSWRRGYRQNFDSSNASQQELKLPHLSQSTVRPSHLPLKNNCRSRNLPAATRVDGEGEILFGGGDALYPCSYPPMGTQWKNRPVGVTQGVPHLRSEQSADH", "length": 930 }, "evidence": [ { "id": "A0A8V0YLZ2", "url": "https://omabrowser.org/oma/group/A0A8V0YLZ2/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q5JTC6-1", "protein_name": "APC membrane recruitment protein 1", "gene_name": "AMER1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "METQKDEAAQAKGAAASGSTREQTAEKGAKNKAAEATEGPTSEPSSSGPGRLKKTAMKLFGGKKGICTLPSFFGGGRSKGSGKGSSKKGLSKSKTHDGLSEAAHGPEDVVSEGTGFSLPLPELPCQFPSSQSAHGALETGSRCKTSVAGATEKAVAEKFPSMPKPKKGLKGFFSSIRRHRKSKVTGAEQSEPGAKGPERVRARPHEHVSSAPQVPCFEETFQAPRKENANPQDAPGPKVSPTPEPSPPATEKMACKDPEKPMEACASAHVQPKPAPEASSLEEPHSPETGEKVVAGEVNPPNGPVGDPLSLLFGDVTSLKSFDSLTGCGDIIAEQDMDSMTDSMASGGQRANRDGTKRSSCLVTYQGGGEEMALPDDDDEEEEEEEEVELEEEEEEVKEEEEDDDLEYLWETAQMYPRPNMNLGYHPTTSPGHHGYMLLDPVRSYPGLAPGELLTPQSDQQESAPNSDEGYYDSTTPGFEDDSGEALGLVRRDCLPRDSYSGDALYEFYEPDDSLENSPPGDDCLYDLHGRSSEMFDPFLNFEPFLSSRPPGAMETEEERLVTIQKQLLYWELRREQLEAQEARAREAHAREAHAREAYTREAYGREAYAREAHTWEAHGREARTREAQAREVRCRETQVRETQARQEKPVLEYQMRPLGPSVMGLAAGVSGTSQISHRGITSAFPTTASSEPDWRDFRPLEKRYEGTCSKKDQSTCLMQLFQSDAMFEPDMQEANFGGSPRRAYPTYSPPEDPEEEEVEKEGNATVSFSQALVEFTSNGNLFSSMSCSSDSDSSFTQNLPELPPMVTFDIADVERDGEGKCEENPEFHNDEDLAASLEAFELGYYHKHAFNNYHSRFYQGLPWGVSSLPRYLGLPGLHPRPPPAAMALNRRSRSLDTAETLEMELSNSHLVQGYLESDELQAQQEDSDEEDEEEEEGEWSRDSPLSLYTEPPGAYDWPAWAPCPLPVGPGPAWISPNQLDRPSSQSPYRQATCCIPPMTMSISLSVPESRAPGESGPQLARPSHLHLPMGPCYNLQPQASQSMRARPRDVLLPVDEPSCSSSSGGFSPSPLPQAKPVGITHGIPQLPRVRPEHPQPQPTHYGPSSLDLSKERAEQGASLATSYSSTAMNGNLAK", "length": 1135 }, "evidence": [ { "id": "A0A8V0YLZ2", "url": "https://omabrowser.org/oma/group/A0A8V0YLZ2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q7TS75-1", "protein_name": "APC membrane recruitment protein 1", "gene_name": "Amer1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MESQQDEAVQTKGASTSSDAQDQGAEKGAKNKTTEATEGPTSEPPLSGPGRLKKTAMKLFGGKKGICTLPSFFGGGRSKGSGKVSSKKSLNKSKTHDGLSEASQGPEDVVIEETDLSTPLSKSSAQFPSSQSANGALEIGSKHKTSGTEAIEKAGVEKVPSVHKPKKSLKSFFSSIRRHRKGKTSGADQSVPGAKELEGARTRSHEHVSSISLPSSEEIFRDTRKENAKPQDAPGPKMSPAQVHFSPTTEKAACKNPEKLTRTCASEFMQPKPVLEGGSLEEPHTSETEGKVVAGEVNPPNGPVGDQLSLLFGDVTSLKSFDSLTGCGDIIAEQDMDSMTDSMASGGQRANRDGTKRSSCLVTYQGGGEEMALPDDDDNDDEEEEEEEEEEEEEEEEEEEEEEEEEEEELLEDEEEVKDGEENDDLEYLWASAQIYPRFNMNLGYHTAISPSHQGYMLLDPVQSYPNLGLGELLTPQSDQQESAPNSDEGYYDSTTPGFEDDSGEALGLAHRDCLPRDSYSGDALYEFYEPDDSLEHSPPGDDCLYDLRGRNSEMLDPFLNLEPFSSRPPGAMETEEERLVTIQKQLLYWELRREQREAQEACAREAHAREAYARDTHTRESYGRNVRARETQALEAHSQEGRVQETKVRQEKPALEYQMRPLGPSVMGLVAGTSGGSQTSHRGTTSAFPATSSSEPDWRDFRPLEKRFEGTCSKKDQSTCLMQLFQSDAMFEPDMQEANFGGSPRKAYPSYSPPEEPEEEEEEKEGNATVSFSQALVEFTSNGNLFTSMSYSSDSDSSFTQNLPELPPMVTFDIADVERDGEGKCEENPEFNNDEDLTASLEAFELGYYHKHAFNSYHSRFYQGLPWGVSSLPRYLGLPGVHPRPPPAAMALNRRSRSLDNAESLELELSSSHLAQGYMESDELQAHQEDSDEEGEEEEGEWGRDSPLSLYTEPPGVYDWPPWAHCPLPVGPGLAWMSPNQLYEPFNQSSYVQATCCVPPVAMPVSVPGRTPGDSVSQLARPSHLPLPMGPCYNLQSQASQSGRAKPRDVLLPVDEPSCSSISGANSQSQAKPVGITHGIPQLPRVRPEPFQLQPNHYRASNLDLSKERGEQGASLSTSYSSTAMNGNLAK", "length": 1132 }, "evidence": [ { "id": "A0A8V0YLZ2", "url": "https://omabrowser.org/oma/group/A0A8V0YLZ2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLZ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLZ2" } ], "pmid": "" }, { "name": "nuclear body", "id": "GO:0016604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016604", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLZ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLZ2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "lipid binding", "id": "GO:0008289", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008289", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLZ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLZ2" } ], "pmid": "" }, { "name": "phosphatidylinositol-4,5-bisphosphate binding", "id": "GO:0005546", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005546", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLZ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLZ2" } ], "pmid": "" }, { "name": "beta-catenin binding", "id": "GO:0008013", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008013", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLZ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLZ2" } ], "pmid": "" }, { "name": "beta-catenin destruction complex binding", "id": "GO:1904713", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904713", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLZ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLZ2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "Wnt signaling pathway", "id": "GO:0016055", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016055", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLZ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLZ2" } ], "pmid": "" }, { "name": "negative regulation of canonical Wnt signaling pathway", "id": "GO:0090090", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090090", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLZ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLZ2" } ], "pmid": "" }, { "name": "positive regulation of protein ubiquitination", "id": "GO:0031398", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031398", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLZ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLZ2" } ], "pmid": "" }, { "name": "positive regulation of protein catabolic process", "id": "GO:0045732", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045732", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLZ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLZ2" } ], "pmid": "" }, { "name": "regulation of canonical Wnt signaling pathway", "id": "GO:0060828", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060828", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLZ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLZ2" } ], "pmid": "" }, { "name": "positive regulation of canonical Wnt signaling pathway", "id": "GO:0090263", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090263", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLZ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLZ2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 305, "end_pos": 307, "annotation": "n_glycosylation_sequon" }, { "start_pos": 636, "end_pos": 638, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 305, "end_pos": 307 }, { "start_pos": 636, "end_pos": 638 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": 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0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YK56-1", "uniprot_ac": "A0A8V0YK56", "uniprot_id": "A0A8V0YK56_CHICK", "mass": { "chemical_mass": 37882.0, "monoisotopic_mass": 37882.0 }, "refseq": { "ac": "XP_420343", "name": "solute carrier family 25 member 43", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_420343" }, "gene_names": [ { "name": "SLC25A43", "type": "recommended", "evidence": [ { "id": "A0A8V0YK56", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK56" } ] }, { "name": "SLC25A43", "type": "synonym", "evidence": [ { "id": "XP_420343", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_420343" } ] } ], "protein_names": [ { "name": "Solute carrier family 25 member 43", "type": "recommended", "evidence": [ { "id": "A0A8V0YK56", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK56/entry#names_and_taxonomy" } ] }, { "name": "solute carrier family 25 member 43", "type": "synonym", "evidence": [ { "id": "XP_420343", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_420343" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052535.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_420343.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_420343", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_420343" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YK56", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK56" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SLC25A43", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK56", "locus": { "chromosome": "4", "start_pos": 16520662, "end_pos": 16538342, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013040", "url": "https://www.ensembl.org/id/ENSGALG00010013040" } ] } } ], "crossref": [ { "id": "A0A8V0YK56", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YK56", "database": "AlphaFoldDB", "categories": [] }, { "id": "422371", "url": "https://www.ncbi.nlm.nih.gov/gene/422371", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002067", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002067", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018108", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018108", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023395", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023395", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:422371", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422371", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QSFMCVG", "url": "https://omabrowser.org/oma/group/QSFMCVG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YK56", "url": "https://www.orthodb.org/?gene=A0A8V0YK56", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24089", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24089", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00153", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00153", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_420343", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_420343", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YK56", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK56", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YK56-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK56-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MATWRRDGRLSGPQRLCCAGLAGALSLSLTAPLELLTVLAQVGTWHCGRGLLGAGRSLCRTEGVRALWKGNLTACLRLCPYSALQLAASRRLVILFTDELGHISHWRAIIAGSLAGMVATVVTYPTDLIKTRLIVQNRLEPSYEGILHAFYKIYHQEGLLALYRGVTPAILGAVPFSAGSFFVYINLDKIWQEPIVCFTPLQNFINGCVAAGVAQTLSFPFETVKRKMQAQSPWLPHCGTVDVHFTGMADCFRQTMKNKGVLGLWSGLTPSLLKIVPYFGVMFSTFEFCKRVCLYRNGYIESPLSYKLTPGVDQSLLPQELRELKHLRRENFEPRKSAVEN", "length": 341, "header": "tr|A0A8V0YK56-1|A0A8V0YK56_CHICK Isoform 1 of Solute carrier family 25 member 43 OS=Gallus gallus OX=9031 GN=SLC25A43 PE=3 SV=1 CANONICAL=A0A8V0YK56-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YK56-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK56/entry#A0A8V0YK56-1", "sequence": { "sequence": "MATWRRDGRLSGPQRLCCAGLAGALSLSLTAPLELLTVLAQVGTWHCGRGLLGAGRSLCRTEGVRALWKGNLTACLRLCPYSALQLAASRRLVILFTDELGHISHWRAIIAGSLAGMVATVVTYPTDLIKTRLIVQNRLEPSYEGILHAFYKIYHQEGLLALYRGVTPAILGAVPFSAGSFFVYINLDKIWQEPIVCFTPLQNFINGCVAAGVAQTLSFPFETVKRKMQAQSPWLPHCGTVDVHFTGMADCFRQTMKNKGVLGLWSGLTPSLLKIVPYFGVMFSTFEFCKRVCLYRNGYIESPLSYKLTPGVDQSLLPQELRELKHLRRENFEPRKSAVEN", "length": 341, "header": "tr|A0A8V0YK56-1|A0A8V0YK56_CHICK Isoform 1 of Solute carrier family 25 member 43 OS=Gallus gallus OX=9031 GN=SLC25A43 PE=3 SV=1 CANONICAL=A0A8V0YK56-1" }, "locus": { "chromosome": "4", "start_pos": 16538303, "end_pos": 16522360, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031259.1", "url": "https://www.ensembl.org/id/ENSGALT00010031259.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018217.1", "url": "https://www.ensembl.org/id/ENSGALP00010018217.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 167, "start_aa": "Thr", "end_pos": 167, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr167", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:422371", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422371", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A2A3V2-1", "protein_name": "Solute carrier family 25 member 43", "gene_name": "Slc25a43", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MATWRRDGRLTGSQRLLCAGLAGAFSLSLTAPLELATVLAQVGKVQSHSLGLWATGRRVWLSEGPRALWKGNGVACLRLFPCSMVQLAAYRKFVVLFMDDLGRISQWSSIVTGSLAGMVSTIVTYPTDLIKTRLMVQNVLEPSYRGLIHAFSTIYQQEGFLALYRGVSLTVLGAVPFSAGSLLVYMNLEKVWNGPRDRFSHLQNFANVCVAAAVSQTLSFPFDTVKRKMQAQSPYLPHYGGVDVHFSGAADCFRQIVKTQGVLGLWNGLTANLLKVVPYFGVMFSMFEFCKRIFLYQNGYTLSPLTYKLTPGVDQSLKPQELRELKKFFKRRKLHSKTPPW", "length": 341 }, "evidence": [ { "id": "A0A8V0YK56", "url": "https://omabrowser.org/oma/group/A0A8V0YK56/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3ZG94-1", "protein_name": "Solute carrier family 25 member 43", "gene_name": "Slc25a43", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MATWRRDGRLTGSQRFLCAGLAGAFSLSLTAPLELATVLAQVGRVQSHSQGLWATGRRVWLSEGPRALWKGNGVACLRLFPCSVVQLAAYRKFVVLFMDDLGRISQWSSIVAGSLAGMVSTIVTYPTDLIKTRLIVQNMLEPSYRGLIHALSTIYQQEGFLALYRGASLTVLGAVPFSAGSLLVYMNLEKIWTGPRDRFSHLQNFATVCVAAAVSQAVSFPFDTVKRKMQAQSPYLPHYGGVDIHFSGAVDCFRQIVKTQGVLGLWNGLTANLLKVVPYFGVMFGMFEFCKRIFLYQNGYTLSPLTYKLTPGVDQSLKPQELRELKKLF", "length": 329 }, "evidence": [ { "id": "A0A8V0YK56", "url": "https://omabrowser.org/oma/group/A0A8V0YK56/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3N0T6-1", "protein_name": "Solute carrier family 25 member 43", "gene_name": "SLC25A43", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MATWRRDGRLTGSQRLLCAGLAGALSLSLTAPLELATVLAQVGVVRGRARGPWAAGLRVWRTEGPRALWKGNAVACLRLFPCSAVQLAAYRKFVVLFMDDLGHISQWSSIMAGSLAGMVSTIVTYPTDLIKTRLIVQNMLEPSYRGILHAFSTIYQQEGFLALYRGVSLTVLGALPFSAGSLLVYMNLEKIWNGPRDQFSLFQNFANVCLAAAVTQTLSFPFDTVKRKMQAQSPYLPHGGGVDVHFSGAMDCFRQIVKAQGVLGLWNGLAANLLKIVPYFGVMFGTFEFCKRICLYQNGYIMSPLSYKLTPGVDQSLKPQELRELNKFFKTGQLKSKKPTL", "length": 341 }, "evidence": [ { "id": "A0A8V0YK56", "url": "https://omabrowser.org/oma/group/A0A8V0YK56/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "K7GPX4-1", "protein_name": "Solute carrier family 25 member 43", "gene_name": "SLC25A43", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MATWRRDGRLTGSQRLLCAGLAGALSLSLTAPLELATVLAQVGVVRGRARGPWAAGLRVWRAEGPRALWKGNAVACLRLFPCSAVQLAAYRKFVVLFTDDLGHISQWRSVMAGSLAGMVSTVVTYPTDLIKTRLIVQNMLEPSYRGIFHAFSTIYQQEGLLAFYRGVSLTVLGALPFSVGSLLVYMNLEKIWNGPRDRFSLLQNFANICLAAAVTQTLSFPFDTVKRKMQAQSPYLPHGGGVDVHFSGAVDCFRQIVKAQGVLGLWNGLAANLLKIVPYFGVMFGTFEFCKRICLYQNGYIMSPLSYKLTPGVDQSLKPQELRELKKFFKTGQLKSKKPTL", "length": 341 }, "evidence": [ { "id": "A0A8V0YK56", "url": "https://omabrowser.org/oma/group/A0A8V0YK56/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q8WUT9-1", "protein_name": "Solute carrier family 25 member 43", "gene_name": "SLC25A43", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MATWRRDGRLTGGQRLLCAGLAGTLSLSLTAPLELATVLAQVGVVRGHARGPWATGHRVWRAEGLRALWKGNAVACLRLFPCSAVQLAAYRKFVVLFTDDLGHISQWSSIMAGSLAGMVSTIVTYPTDLIKTRLIMQNILEPSYRGLLHAFSTIYQQEGFLALYRGVSLTVVGALPFSAGSLLVYMNLEKIWNGPRDQFSLPQNFANVCLAAAVTQTLSFPFETVKRKMQAQSPYLPHSGGVDVHFSGAVDCFRQIVKAQGVLGLWNGLTANLLKIVPYFGIMFSTFEFCKRICLYQNGYILSPLSYKLTPGVDQSLQPQELRELKKFFKTRKPKPKKPTL", "length": 341 }, "evidence": [ { "id": "A0A8V0YK56", "url": "https://omabrowser.org/oma/group/A0A8V0YK56/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9M024-1", "protein_name": "Thylakoid ADP,ATP carrier protein, chloroplastic", "gene_name": "TAAC", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MGEEKSLLQFRSFPSLKTSDFALTEEPSWRLENNVSSNRRRGNKRSGGVFTNFASLSVAIRRDRRESTFNGRNGGGGGAFASVSVVIPKEEDEFAPTSAQLLKNPIALLSIVPKDAALFFAGAFAGAAAKSVTAPLDRIKLLMQTHGVRAGQQSAKKAIGFIEAITLIGKEEGIKGYWKGNLPQVIRIVPYSAVQLFAYETYKKLFRGKDGQLSVLGRLGAGACAGMTSTLITYPLDVLRLRLAVEPGYRTMSQVALNMLREEGVASFYNGLGPSLLSIAPYIAINFCVFDLVKKSLPEKYQQKTQSSLLTAVVAAAIATGTCYPLDTIRRQMQLKGTPYKSVLDAFSGIIAREGVVGLYRGFVPNALKSMPNSSIKLTTFDIVKKLIAASEKEIQRIADDNRKKASPNTIDEQT", "length": 415 }, "evidence": [ { "id": "A0A8V0YK56", "url": "https://omabrowser.org/oma/group/A0A8V0YK56/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YK56", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK56" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "transmembrane transport", "id": "GO:0055085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055085", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YK56", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK56" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 71, "end_pos": 73, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 167 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 71, "end_pos": 73 } ] }, "class_list": [], "section_stats": [ { "table_id": 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{ "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YK62-1", "uniprot_ac": "A0A8V0YK62", "uniprot_id": "A0A8V0YK62_CHICK", "mass": { "chemical_mass": 299372.0, "monoisotopic_mass": 299372.0 }, "refseq": { "ac": "XP_015138787", "name": "otogelin-like protein isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015138787" }, "gene_names": [ { "name": "OTOGL", "type": "recommended", "evidence": [ { "id": "A0A8V0YK62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK62" } ] }, { "name": "OTOGL", "type": "synonym", "evidence": [ { "id": "XP_015138787", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015138787" } ] } ], "protein_names": [ { "name": "Otogelin like", "type": "synonym", "evidence": [ { "id": "A0A8V0YK62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK62/entry#names_and_taxonomy" } ] }, { "name": "otogelin-like protein isoform X2", "type": "synonym", "evidence": [ { "id": "XP_015138787", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015138787" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015138787.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015138787", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015138787" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YK62", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK62" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "OTOGL", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK62", "locus": { "chromosome": "1", "start_pos": 39949196, "end_pos": 39853230, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013364", "url": "https://www.ensembl.org/id/ENSGALG00010013364" } ] } } ], "crossref": [ { "id": "cd19941", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd19941", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "772154", "url": "https://www.ncbi.nlm.nih.gov/gene/772154", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000742", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000742", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001007", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001007", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001846", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001846", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002919", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002919", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006207", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006207", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007934", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007934", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014853", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014853", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036084", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036084", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036195", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036195", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050780", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050780", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR058753", "url": "https://www.ebi.ac.uk/interpro/entry/IPR058753", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR058754", "url": "https://www.ebi.ac.uk/interpro/entry/IPR058754", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR058755", "url": "https://www.ebi.ac.uk/interpro/entry/IPR058755", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YK62", "url": "https://www.orthodb.org/?gene=A0A8V0YK62", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11339", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11339", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11339:SF225", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11339:SF225", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00094", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00094", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01826", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01826", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF05270", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05270", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08742", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08742", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25960", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25960", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25961", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25961", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25962", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25962", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015138787", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015138787", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YK62", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK62", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YK62-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK62-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNFLLLSYTEMNIVGKLNLMIPWSIFLLHSLLSSLQGTYCKLSLLRRTSRNEFNATRQKRDLLTTEVRAASPQSHLNGTLTWSPPRGLCPQKCLNGAGCTEAGDCDCQLFQAQGSRCQIVPNNGKDRDGICKSWGQYHFETFDGIYYYFPGNCSYIFAKDCGTPEPHYTVWVHNSPHCHGSVYSCQRSISLFFSNQEEITISGHEVRKEGNRLMLPQTVGNVFFERLADYILVKTTFGFSLAWDGNSGIYIKLTEDHHGKPCGLCGNFNGDKYDDLILQNRGEYTEDIAEFANSWAVQISDDAACVPTALDFSSPCSANAESTEDIFFKCQIFLQFPFLSCHESIDPYSYISSCMNDLCRVDDDETYCRAVTEYARACSHAGSPVRDWRDDFPACTEKCEDSFVHRDCISCCPPTCTFEKDCLGSNLHCLDGCYCPDGLIMENGTCISVSNCPCIYHGTAFPVGSKIEQECSNCVCIGGIWNCTDHDCPAECSVTGNSHFTTFDGRHFTFLGICQYILVKGTGKNKFTVTLQKTPCGHNFDHACIESITLVLEDDVSKQVTLTRYGQVQTGPNQGLNINGAIEIQNISSLFVQLKTTFGLKILFAKDGERIYVQVDINWKRRTLGLCGTYNGNLRDDFLSPAGMIEGTPQLHANAWKVSSACSVPINVPVVDPCNINQQNIGYASHCDIINEEVFAPCHAYISPGLYYQLCRFDACKCGSSCMCNSLAHYAYVCGKHGIAVDFRSHISYCAAMCHSGMLYHQCSSFCKHSCASLSMANICGDDCAEGCNCPDGKYFEESVNFCVSISACHCHYKGKVLQPGEILPLPTGSCQCLNGTVKCIEATSENTVHICPEGKIYYDCRSPVPGLPAAGVNCGISCANLAMNFSCVPSPPCASGCICPPGMAEHRGKCYIPDSCPCTWKDREFLSGEVISTPCYTCVCRRGVFNCTSYPCPAVCTIYGDRHYYTFDGLEYDYASDCQAYLLKSTDNSNISVIAQNKKCFDNDIVCSKNIFIAVGDSEIYFSELSEKQSTLRGQENKSNYQVWMAGYYTVIHFPEQDITILWDKKTMMHVKVGPQWKGKLAGLCGNFDKYTSNDLTTSNNMEVRNAQVFGDSWVLGQCKSPNGTLRPCEVHQSKFPYAKKECSILYSDVFAPCRNVIDVTSFVKNCHTDTCNCNLAGDCECLCTSIAAYAHKCCQHGAVIHWRSPSLCAYDCESYNQGLGEGPYILASSGENDTIIGANISSRRIFPLPRNTAYGNVFFSFMITPGLFKDKDLSLSLVSLECAERPNYFLYVHADETVGLEQWQASTSFQRRATFFHHQGLWSPGLSAFELHSKKGFFIILTSSGVKVAKYDDSEEFKRMSSFSIEELSASVPYRKMCEWRYESCANPCFKTCSDPEGTACKFLPPVEGCLPYCPKNMILDEVTLKCVYPEDCIPVKPMGSATGTKPSLLISHPVATTERFPTTPPIHVTSWTESSGTDMTVKITMKTNTTLARMNISAQSVTDLYSLEDATYSAYSLPRKHSSSVSSSAEDGTVSVISAGIITQSTTSVIVNTTVNATSLKTPYTFAKILPSSSASVLVASDTTVDPRITAKTTDDFADSKLHMASASVPTTIETPTYESHKSLLTFAPSEVSQSSKEIPKTTVMKMSTTSPPLSKTKSTSFTTSEFKYVTSFERTVGILESSQTSYVQRNVTKAKSTTTEKPFLPYLTVSASRSSPFSSVRITSAKNLSEVLDAKASDWSKILTQTTIKPYFNLTEHSELQDRTLIDFSHSSGEMALSSPSPMETQTSLASTDTVTTIADKTLFGTVMHTLMSSSSECVPRYLEPVDKCSQYVCVHTSWMLYNLSKNCLKDVQKPDCGFRGMPVQVNNDSCCPEWECPCQCSVLSELSVITFDGNNIALCNMASYVLVKLPGEIIVAHIEKCPANQSANSIRKIVPPASTSGLCFKKLNVTTQTSELLINRLERKVVVDSVIPSLPFSKEGLSIQDTGAMYVINTPAGISIKWAHITGIIDIQYGLHSNTSIKTEGLCGVCNGDPTDDLKMQNRTIITNMEEIEVFIKSWEIEKSLDVTTRRPVRNCTEDNCTYCMELLNKSVFIHCHNKVSPQEFCEKMWINSTYFWNYECDALSAYVALCNKHNICIKWRTPDYCPLSCPEGKEYQPCVKPCEAKTCLNKWLYEDSPCSYLREDCVCKSGTVLHRTDSDLCIPEEKCTCTDNRGQPRSAGEIWNGSMRGCCIYSCLENGSIVAVEPECNEDPPPACEREGEMIVLVMEVEDCCPKKVCECNMSLCDAIIPTCKRSEKLIVGYSPLSCCPQYRCECDPSVCFNSSQLDCREDQFIVEAKLEDPCCFSYLCVCESCIEPVPLCNEGEILTVDLHTIHYCCPHYYCVCDENFCPEPPMNCTDDMMVVKEKVPGQCCPEWHCECSCENITTRTCKLGEVQKIDSSISSACGCTHYICEKDDVCIFQEVTVLNPGQSVIQYLDGDLCYTVQCLREKDQNTGYNAMHFTTVNCSQQCEAHQLYIPSSSHHSCCGTCQNVSCSFLTENGTRIVYEEGSTWISNCTNYTCAKTVLGAMIVGSGVVCPPFNDTECTKNGGIVQTYNDGCCKTCKKEERICQKMTIRTTIRKNDCISQSPINVASCDGKCPSATIFNVNIDSHLRFCKCCREHGTRNLTVPLHCSGNGTEIMYVIQEPVDCSCQWN", "length": 2702, "header": "tr|A0A8V0YK62-1|A0A8V0YK62_CHICK Isoform 1 of Otogelin like OS=Gallus gallus OX=9031 GN=OTOGL PE=3 SV=1 CANONICAL=A0A8V0YK62-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YK62-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK62/entry#A0A8V0YK62-1", "sequence": { "sequence": "MNFLLLSYTEMNIVGKLNLMIPWSIFLLHSLLSSLQGTYCKLSLLRRTSRNEFNATRQKRDLLTTEVRAASPQSHLNGTLTWSPPRGLCPQKCLNGAGCTEAGDCDCQLFQAQGSRCQIVPNNGKDRDGICKSWGQYHFETFDGIYYYFPGNCSYIFAKDCGTPEPHYTVWVHNSPHCHGSVYSCQRSISLFFSNQEEITISGHEVRKEGNRLMLPQTVGNVFFERLADYILVKTTFGFSLAWDGNSGIYIKLTEDHHGKPCGLCGNFNGDKYDDLILQNRGEYTEDIAEFANSWAVQISDDAACVPTALDFSSPCSANAESTEDIFFKCQIFLQFPFLSCHESIDPYSYISSCMNDLCRVDDDETYCRAVTEYARACSHAGSPVRDWRDDFPACTEKCEDSFVHRDCISCCPPTCTFEKDCLGSNLHCLDGCYCPDGLIMENGTCISVSNCPCIYHGTAFPVGSKIEQECSNCVCIGGIWNCTDHDCPAECSVTGNSHFTTFDGRHFTFLGICQYILVKGTGKNKFTVTLQKTPCGHNFDHACIESITLVLEDDVSKQVTLTRYGQVQTGPNQGLNINGAIEIQNISSLFVQLKTTFGLKILFAKDGERIYVQVDINWKRRTLGLCGTYNGNLRDDFLSPAGMIEGTPQLHANAWKVSSACSVPINVPVVDPCNINQQNIGYASHCDIINEEVFAPCHAYISPGLYYQLCRFDACKCGSSCMCNSLAHYAYVCGKHGIAVDFRSHISYCAAMCHSGMLYHQCSSFCKHSCASLSMANICGDDCAEGCNCPDGKYFEESVNFCVSISACHCHYKGKVLQPGEILPLPTGSCQCLNGTVKCIEATSENTVHICPEGKIYYDCRSPVPGLPAAGVNCGISCANLAMNFSCVPSPPCASGCICPPGMAEHRGKCYIPDSCPCTWKDREFLSGEVISTPCYTCVCRRGVFNCTSYPCPAVCTIYGDRHYYTFDGLEYDYASDCQAYLLKSTDNSNISVIAQNKKCFDNDIVCSKNIFIAVGDSEIYFSELSEKQSTLRGQENKSNYQVWMAGYYTVIHFPEQDITILWDKKTMMHVKVGPQWKGKLAGLCGNFDKYTSNDLTTSNNMEVRNAQVFGDSWVLGQCKSPNGTLRPCEVHQSKFPYAKKECSILYSDVFAPCRNVIDVTSFVKNCHTDTCNCNLAGDCECLCTSIAAYAHKCCQHGAVIHWRSPSLCAYDCESYNQGLGEGPYILASSGENDTIIGANISSRRIFPLPRNTAYGNVFFSFMITPGLFKDKDLSLSLVSLECAERPNYFLYVHADETVGLEQWQASTSFQRRATFFHHQGLWSPGLSAFELHSKKGFFIILTSSGVKVAKYDDSEEFKRMSSFSIEELSASVPYRKMCEWRYESCANPCFKTCSDPEGTACKFLPPVEGCLPYCPKNMILDEVTLKCVYPEDCIPVKPMGSATGTKPSLLISHPVATTERFPTTPPIHVTSWTESSGTDMTVKITMKTNTTLARMNISAQSVTDLYSLEDATYSAYSLPRKHSSSVSSSAEDGTVSVISAGIITQSTTSVIVNTTVNATSLKTPYTFAKILPSSSASVLVASDTTVDPRITAKTTDDFADSKLHMASASVPTTIETPTYESHKSLLTFAPSEVSQSSKEIPKTTVMKMSTTSPPLSKTKSTSFTTSEFKYVTSFERTVGILESSQTSYVQRNVTKAKSTTTEKPFLPYLTVSASRSSPFSSVRITSAKNLSEVLDAKASDWSKILTQTTIKPYFNLTEHSELQDRTLIDFSHSSGEMALSSPSPMETQTSLASTDTVTTIADKTLFGTVMHTLMSSSSECVPRYLEPVDKCSQYVCVHTSWMLYNLSKNCLKDVQKPDCGFRGMPVQVNNDSCCPEWECPCQCSVLSELSVITFDGNNIALCNMASYVLVKLPGEIIVAHIEKCPANQSANSIRKIVPPASTSGLCFKKLNVTTQTSELLINRLERKVVVDSVIPSLPFSKEGLSIQDTGAMYVINTPAGISIKWAHITGIIDIQYGLHSNTSIKTEGLCGVCNGDPTDDLKMQNRTIITNMEEIEVFIKSWEIEKSLDVTTRRPVRNCTEDNCTYCMELLNKSVFIHCHNKVSPQEFCEKMWINSTYFWNYECDALSAYVALCNKHNICIKWRTPDYCPLSCPEGKEYQPCVKPCEAKTCLNKWLYEDSPCSYLREDCVCKSGTVLHRTDSDLCIPEEKCTCTDNRGQPRSAGEIWNGSMRGCCIYSCLENGSIVAVEPECNEDPPPACEREGEMIVLVMEVEDCCPKKVCECNMSLCDAIIPTCKRSEKLIVGYSPLSCCPQYRCECDPSVCFNSSQLDCREDQFIVEAKLEDPCCFSYLCVCESCIEPVPLCNEGEILTVDLHTIHYCCPHYYCVCDENFCPEPPMNCTDDMMVVKEKVPGQCCPEWHCECSCENITTRTCKLGEVQKIDSSISSACGCTHYICEKDDVCIFQEVTVLNPGQSVIQYLDGDLCYTVQCLREKDQNTGYNAMHFTTVNCSQQCEAHQLYIPSSSHHSCCGTCQNVSCSFLTENGTRIVYEEGSTWISNCTNYTCAKTVLGAMIVGSGVVCPPFNDTECTKNGGIVQTYNDGCCKTCKKEERICQKMTIRTTIRKNDCISQSPINVASCDGKCPSATIFNVNIDSHLRFCKCCREHGTRNLTVPLHCSGNGTEIMYVIQEPVDCSCQWN", "length": 2702, "header": "tr|A0A8V0YK62-1|A0A8V0YK62_CHICK Isoform 1 of Otogelin like OS=Gallus gallus OX=9031 GN=OTOGL PE=3 SV=1 CANONICAL=A0A8V0YK62-1" }, "locus": { "chromosome": "1", "start_pos": 39948192, "end_pos": 39856804, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032183.1", "url": "https://www.ensembl.org/id/ENSGALT00010032183.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018973.1", "url": "https://www.ensembl.org/id/ENSGALP00010018973.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YK62", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK62" } ], "pmid": "" }, { "name": 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"table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YK70-1", "uniprot_ac": "A0A8V0YK70", "uniprot_id": "A0A8V0YK70_CHICK", "mass": { "chemical_mass": 50774.0, "monoisotopic_mass": 50774.0 }, "refseq": { "ac": "XP_040503156", "name": "5-phosphohydroxy-L-lysine phospho-lyase isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040503156" }, "gene_names": [ { "name": "PHYKPL", "type": "recommended", "evidence": [ { "id": "A0A8V0YK70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK70" } ] }, { "name": "PHYKPL", "type": "synonym", "evidence": [ { "id": "XP_040503156", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040503156" } ] } ], "protein_names": [ { "name": "5-phosphohydroxy-L-lysine phospho-lyase isoform X1", "type": "synonym", "evidence": [ { "id": "XP_040503156", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040503156" } ] }, { "name": "5-phosphohydroxy-L-lysine phospho-lyase", "type": "synonym", "evidence": [ { "id": "A0A8V0YK70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK70/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052544.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040503156", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040503156" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YK70", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK70" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PHYKPL", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK70", "locus": { "chromosome": "13", "start_pos": 13903717, "end_pos": 13895366, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010015182", "url": "https://www.ensembl.org/id/ENSGALG00010015182" } ] } } ], "crossref": [ { "id": "A0A8V0YK70", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YK70", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00610", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00610", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "416374", "url": "https://www.ncbi.nlm.nih.gov/gene/416374", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR005814", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005814", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015421", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015421", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015422", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015422", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015424", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015424", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR049704", "url": "https://www.ebi.ac.uk/interpro/entry/IPR049704", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "REGLNQH", "url": "https://omabrowser.org/oma/group/REGLNQH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YK70", "url": "https://www.orthodb.org/?gene=A0A8V0YK70", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YRP9", "url": "https://www.orthodb.org/?gene=A0A8V0YRP9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45688", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45688", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45688:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45688:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00202", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00202", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-1442490", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1442490", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-71064", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-71064", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_040503156", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040503156", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YK70", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK70", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YK70-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK70-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YRP9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRP9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YRP9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRP9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRRAQRSRQETLTLRRQLIGSSCKLFYPNDPLKIVKARGQYMYDENGRQYLDCINNVAHVGHCHPDVVKAAHEQNQLLNTNSRYLHDNLTDYAERLSEKLPEKLCTFYFLNSGSEANDLALRMARQFTKHEDVIVLDHAYHGHLTSLIDISPYKFRNLEGQKEWVHVAPVPDTYRGLYREDHEDPATAYATEVKNIIERAHKKGREIAAFFAESLPSVGGQIIPPEGYFQKVAEHVHKAGGVFVADEIQVGFGRVGKHFWAFQLQGEEFIPDIVTMGKPIGNGHPIACVATTKEIAEAFAATGVEYFNTFGGNPVSCAIGLAVLDVIEKEQLQIHATEVGNFLMKLLTEQKVKHPIIGDVRGSGLFIGVDLIKDQAKRTPATEEAEYLITRLKEEYILLSTDGPGRNVLKFKPPMCFTMEDAKFVVDTIDKLLTDMEKEHMNQEKTSTGST", "length": 451, "header": "tr|A0A8V0YK70-1|A0A8V0YK70_CHICK Isoform 1 of 5-phosphohydroxy-L-lysine phospho-lyase OS=Gallus gallus OX=9031 GN=PHYKPL PE=1 SV=1 CANONICAL=A0A8V0YK70-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YK70-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK70/entry#A0A8V0YK70-1", "sequence": { "sequence": "MRRAQRSRQETLTLRRQLIGSSCKLFYPNDPLKIVKARGQYMYDENGRQYLDCINNVAHVGHCHPDVVKAAHEQNQLLNTNSRYLHDNLTDYAERLSEKLPEKLCTFYFLNSGSEANDLALRMARQFTKHEDVIVLDHAYHGHLTSLIDISPYKFRNLEGQKEWVHVAPVPDTYRGLYREDHEDPATAYATEVKNIIERAHKKGREIAAFFAESLPSVGGQIIPPEGYFQKVAEHVHKAGGVFVADEIQVGFGRVGKHFWAFQLQGEEFIPDIVTMGKPIGNGHPIACVATTKEIAEAFAATGVEYFNTFGGNPVSCAIGLAVLDVIEKEQLQIHATEVGNFLMKLLTEQKVKHPIIGDVRGSGLFIGVDLIKDQAKRTPATEEAEYLITRLKEEYILLSTDGPGRNVLKFKPPMCFTMEDAKFVVDTIDKLLTDMEKEHMNQEKTSTGST", "length": 451, "header": "tr|A0A8V0YK70-1|A0A8V0YK70_CHICK Isoform 1 of 5-phosphohydroxy-L-lysine phospho-lyase OS=Gallus gallus OX=9031 GN=PHYKPL PE=1 SV=1 CANONICAL=A0A8V0YK70-1" }, "locus": { "chromosome": "13", "start_pos": 13902286, "end_pos": 13895391, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010036585.1", "url": "https://www.ensembl.org/id/ENSGALT00010036585.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021329.1", "url": "https://www.ensembl.org/id/ENSGALP00010021329.1" } ] } }, { "isoform_ac": "A0A8V0YRP9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK70/entry#A0A8V0YRP9-1", "sequence": { "sequence": "MRRAQRSRQETLTLRRQLIGSSCKLFYPNDPLKIVKARGQYMYDENGRQYLDCINNVAHVGHCHPDVVKAAHEQNQLLNTNSRYLHDNLTDYAERLSEKLPEKLCTFYFLNSGSEANDLALRMARQFTKHEDVIVLDHAYHGHLTSLIDISPYKFRNLEGQKEWVHVAPVPDTYRGLYREDHEDPATAYATEVKNIIERAHKKGREIAAFFAESLPSVGGQIIPPEGYFQKVAEHVHKAGGVFVADEIQVGFGRVGKHFWAFQLQGEEFIPDIVTMGKPIGNGHPIACVATTKEIAEAFAATGVEYFNTFGGNPVSCAIGLAVLDVIEKEQLQIHATEVGNFLMKLLTEQKVKHPIIGDVRGSGLFIGVDLIKDQAKRTPATEEAEYLITRYMRQSCGFAVC", "length": 402, "header": "tr|A0A8V0YRP9-1|A0A8V0YRP9_CHICK Computationally mapped isoform of 5-phosphohydroxy-L-lysine phospho-lyase OS=Gallus gallus OX=9031 GN=PHYKPL PE=1 SV=1 CANONICAL=A0A8V0YK70-1" }, "locus": { "chromosome": "13", "start_pos": 13901553, "end_pos": 13895391, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010036584.1", "url": "https://www.ensembl.org/id/ENSGALT00010036584.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021328.1", "url": "https://www.ensembl.org/id/ENSGALP00010021328.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-1442490", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1442490", "resource": "Reactome", "description": "Collagen degradation" }, { "id": "R-GGA-71064", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-71064", "resource": "Reactome", "description": "Lysine catabolism" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287BCJ7-1", "protein_name": "5-phosphohydroxy-L-lysine phospho-lyase", "gene_name": "PHYKPL", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAADPREKAATLALRRRLLSNSCKLFFPEDPIKIVRGQGQYMYDEEGAEYIDCINNVAHVGHCHPLVVQAAHEQNQVLNTNSRYLHDNIVDYAQRLSETLPEKLCVFYFLNSGSEANDLALRLARQYTGHWDVVVLDHAYHGHLSSLIDISPYKFRDLDGQKEWVHVAPLPDTYRGLYREDHPNPAVAYASEVKRVVSSAQEKGRKIAAFFAESLPSVGGQIVPPAGFFPEVAEHIHKAGGVFVADEIQVGFGRVGKHFWAFQLQGEDFVPDIVTMGKSIGNGHPVACVATTQAVARAFEATGVEYFNTFGGSPVSCAVGLAVLDVLEKEQLQAHAACVGSFLMELLRQQKAKHPILGDIRGVGLFIGVDLIKDEATRMPATEEADYVVSRLKENYILLSTDGPGRNVLKFKPPMCFSLDNARHVVAKLDTILTDMEEKVRSCKTLRRVL", "length": 450 }, "evidence": [ { "id": "A0A8V0YK70", "url": "https://omabrowser.org/oma/group/A0A8V0YK70/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8J8XD81-1", "protein_name": "5-phosphohydroxy-L-lysine phospho-lyase", "gene_name": "Phykpl", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAADRRAKAATLDLRRRLLSSSCRLFFPENPVKIIRGQGQYLYDEQGREYLDCINNVAHVGHCHPTVVQAAHEQNLVLNTNSRYLHDNIVDYAQRLSETLPEKLSVFYFLNSGSEANDLALRLARQYTGHQDVVVLDHAYHGHLSSLIDISPYKFRNLDGQKEWVHVAPLPDTYRGPYREDHPDPAGAYASEVKHVISSAQKKGRKIAAFFAESLPSVSGQIIPPAGYFSQVAEHIRRAGGLFVADEIQVGFGRVGKHFWAFQLEGEDFVPDIVTMGKSIGNGHPVACLATTQAVSRAFEATGVEYFNTFGGNPVSCAVGLAVLDVLKTEQLQAHATNVGSFLMEHLSQQKAKHPIIGDVRGTGLFIGVDLIKDETLRTPATEEAEYLVSRLKENYILLSTDGPGRNILKFKPPMCFSLDNAQHVVAKLDDILTDMEEKVRSCETLRIKHPPGSTGPGCRAAAGSRPSNLEQGNLVIKSAP", "length": 481 }, "evidence": [ { "id": "A0A8V0YK70", "url": "https://omabrowser.org/oma/group/A0A8V0YK70/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E1B8R9-1", "protein_name": "5-phosphohydroxy-L-lysine phospho-lyase", "gene_name": "PHYKPL", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAADQRGKAATLALRRRLLSNSCRLFFPEDPIKIVRGQGQYMYDEQGAEYIDCINNVAHVGHCHPLVVQAAHEQNQVLNTNSRYLHDNIVDYAQRLSETLPEKLCVFYFLNSGSEANDLALRLARQYTGHWDVVVLDHAYHGHLSSLIDISPYKFRDLDGQKEWVHVAPLPDTYRGPYREDHPNPAVAYASEVKRVVSSAQEKGRKIAAFFAESLPSVGGQIIPPAGYFPEVAGHIRRAGGVFVADEIQVGFGRVGKHFWAFQLQGEDFVPDIVTMGKSIGNGHPVACVATTQAVARAFEATGVEYFNTFGGSPVSCAVGLAVLDVLEKEQLQAHAACVGSFLMELLGQQKAKHPILGDIRGVGLFIGVDLIKDEATRMPATEEADYVVSRLKENYILLSTDGPGRNVLKFKPPMCFSLDNARHVVAKLDAILTDMEAKVRSCETLRLHS", "length": 450 }, "evidence": [ { "id": "A0A8V0YK70", "url": "https://omabrowser.org/oma/group/A0A8V0YK70/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q1ZXC3-1", "protein_name": "Aminotransferase class-III", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MITRGVIKNIKTTSVLINNSIKSTQCSFSSKVNYDEIYKKHLKISEKKFNKKEIIQTIKDNTLFSWNPTEAAANKALIMEKGEGVYFYDTDGKKYIDFNSQAMCSNLGHTVPEEVIKAIEEQLRSAAYAYPCSIVTPIKAKLSMLLADLFPGDINHFYYTSGGAESNETAMRMARLFTGRHKILARYRSYHGATLGAMTLTGDPRRWNSEPGASGVVHFMDPYPYSFKWGETEEQITEISLKYLRETISYEGAKNIAAIFIEPVTGTNGILKPPKGYLEGIRKICDETGILMVCDEVMNGFGRTGEMFGFMNSQEEVIPDIVTMAKGINGAYLPLGAVGCRDRIADHFKVNPIGIGSTYNSHPVTLASAYAALQYFLKNRVLDNVKTLEPVMKKHMEQLKQRHPTVKGYRSLGLFGIVELQKNSNGDPFIEYNGPPHPAMTKLSSDFVENGLYTLCRWSSFFTNPPLTINEKELKEGFEILDKSLTNLDKHFEK", "length": 494 }, "evidence": [ { "id": "A0A8V0YK70", "url": "https://omabrowser.org/oma/group/A0A8V0YK70/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q8IUZ5-1", "protein_name": "5-phosphohydroxy-L-lysine phospho-lyase", "gene_name": "PHYKPL", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAADQRPKADTLALRQRLISSSCRLFFPEDPVKIVRAQGQYMYDEQGAEYIDCISNVAHVGHCHPLVVQAAHEQNQVLNTNSRYLHDNIVDYAQRLSETLPEQLCVFYFLNSGSEANDLALRLARHYTGHQDVVVLDHAYHGHLSSLIDISPYKFRNLDGQKEWVHVAPLPDTYRGPYREDHPNPAMAYANEVKRVVSSAQEKGRKIAAFFAESLPSVGGQIIPPAGYFSQVAEHIRKAGGVFVADEIQVGFGRVGKHFWAFQLQGKDFVPDIVTMGKSIGNGHPVACVAATQPVARAFEATGVEYFNTFGGSPVSCAVGLAVLNVLEKEQLQDHATSVGSFLMQLLGQQKIKHPIVGDVRGVGLFIGVDLIKDEATRTPATEEAAYLVSRLKENYVLLSTDGPGRNILKFKPPMCFSLDNARQVVAKLDAILTDMEEKVRSCETLRLQP", "length": 450 }, "evidence": [ { "id": "A0A8V0YK70", "url": "https://omabrowser.org/oma/group/A0A8V0YK70/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8R1K4-1", "protein_name": "5-phosphohydroxy-L-lysine phospho-lyase", "gene_name": "Phykpl", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAADTRAKAVTLDLRRRLLSSSCRLFFPEDPVKIIRGQGQYLYDEQGREYLDCINNVAHVGHCHPTVVQAAHEQNLVLNTNSRYLHDNIVDYAQRLSETLPEQLSVFYFLNSGSEANDLALRLARQYTGHQDVVVLDHAYHGHLSSLIDISPYKFRNLGGQKEWVHVAPLPDTYRGPYREDHPNPAEAYANEVKHVISSAQQKGRKIAAFFAESLPSVSGQIIPPAGYFSQVAEHIHRAGGLFVADEIQVGFGRIGKHFWAFQLEGEDFVPDIVTMGKSIGNGHPVACMATTQAVSRAFEATGVEYFNTFGGNPVSCAVGLAVLDVLKTEQLQAHATNVGSFLLEHLTQQKAKHPIIGDVRGTGLFIGVDLIKDETLRTPATEEAEYLVSRLKENYILLSIDGPGKNILKFKPPMCFNVDNAQHVVAKLDDILTDMEEKVRSCETLRIKHPPEDTHPTQILLTRQQD", "length": 467 }, "evidence": [ { "id": "A0A8V0YK70", "url": "https://omabrowser.org/oma/group/A0A8V0YK70/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "pyridoxal phosphate binding", "id": "GO:0030170", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030170", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YK70", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK70" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YK70", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK70" } ], "pmid": "" }, { "name": "lyase activity", "id": "GO:0016829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YK70", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK70" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 88, "end_pos": 90, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" 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"PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00094", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00094", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF06119", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06119", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23263", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23263", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-913709", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-913709", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-977068", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-977068", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YK63", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK63", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YK63-1", "url": 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"MVTAVSLPDGVPGGGYSTRTQVSTGVSAAQPSGSTFGWAAERVTSRFGSNPYGPGTATLSPVSHSPTEKGMGTSVPSGSSTTPMKSVGSPRALQSTAGQPTLGTAVPLQEITVTEEHVSAISMLTGGIPTPTGSLSPAVIDVSAAPLVLGTEAPSSATSTANDDNGLGQPHSAVTAEGTPGTAQGTVLSDVQHSTGTSPHSLTWIPAELHTAAVRLSQEVMPGLAEATSPLVTAASVTAGDTEPASTMSDRVTSPTVPATTGSPHHDGIQKSDTTILPGSVSATITPSPATDGVSEATAPGLPAPGTAGDGLHRDTAVTHSRVTSQLHVTTAPALGTSTTAVDVTTASHVPTTPFPALGSAETVSITAEATSGYDVLQTEGTPMELGMGTVPSVVPSVSLRDGSTAGQMMGSAALGLGSSTQASTGSIPSENPTVGVPAATANTESTSMVSALPAPHPSSASTTAHLGTATPNHSHSTAQVTVNTDSSSATNPVAGGAEPGVRRVTPLSPSALDSQRPPISLASVTALSPALSRSAAEQDVSVSPSVFQNSSLAVVASSVTPTVVASITPSASVTAPAMVSPSITPSVSATNPALGTRDASQSMVTTPSFAAPSISLGPHSPHVTRGTPINATSSPSAPTLRDSSTRAWEATALSWKDTVPSSNAITPSGSPSIDTPTVTRHTTVSPPTAKATSSAQSPSAMHNVPTALRVTNRKATSAFAAMSSPSKGTPAASSPTSTAPGLGAQSGPVTAPGTPTYATSRNAVFKPGTELGKSVFFPFPNMKERRGPSALFSQLKGENSLNICSHSRPAPGHALTPGAMSICRHPPTHTIRTSPINALPVSVPAVSLYPFGAAEGDTECVQRTVDFNSPLLRPEIGFPLGKALRDTLYFTDNGQIIFPPTDSHMPSSPHPPSQGFSSHEALPMVAAFWDDADFSRGVGTTWYQEYPTLGSIQYPIIRDVEAKIQKYLQVPYSAKWTLKVTWEKAPAFPSQLDDTNTYQAVLSTDGSRSFALLLYQDGGMRWDYARLAARDALIGFSSGDGYAQNSELTKEPPAVRYRPDQQRSSGMDVRGLWLFRLDRHSRVNYRLQCLTWLQAQPPPSTWSMELPPCPCSQPQADTQPLSAHRWGAGGICATYPCDAHTSFVLQGRMARTGTAQATNFMAFVAQYTSSTTTTVEWTLGSRNEIHVLLNYETIQFSYSQDMGAEVYYSPSVLLVNTSSITAVFNGTISISVSASSGMLSAVCSLLEQYRNGTRGLLGVWNDNPADDFQMPNGTNIPVNSSEEDVFCYGMTWAVGEHSLFAQPLAAPVRTFNPIFLSQLRQENESQYQLAASQCGGCRECIYDMLSTGDVALGLATQSLVEDFQKRKAALSKWGVGNVEETEQVTRQYRATGPGVRFVPHVSPELNDGMLTWEPRGTAPLSITLQAVSPHLPPALLQLSFTLCSCRSIQQCDYNSTTTIASSSLQVAKCDDGYWGPFCQHEPDPCAQGCFPGVGCDPHTGCGPCPPGLTGDGRHCAGESLGCGTACRSRSCPEGFCSNGGHSFTDRHCVVAGGDFQPQANLPQRSVLLWVRALQSVTAEEVNATVCSGGGRAVAWGALALPPQGSTDGLTFAVVAEFTYNSSSFVIRFLNEELTAAITTAFNGRRARRDVGAYLLFALSVPELQHYFSCTLSGYEGYQLDYVGTVGLICISPCKKGYCQHSGRCQHLPEGPTCSCVPFSIFSPGGARCEQLAVSLTAFISIMVGALALLCLLFSIARNGVCAGAVWLFLLNPCPTAPCSVTAPHMGG", "length": 1788, "header": "tr|A0A8V0YK80-1|A0A8V0YK80_CHICK Isoform 1 of Mucin-4 OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0YK80-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YK63-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK80/entry#A0A8V0YK63-1", "sequence": { "sequence": "MVTTPSFAAPSISLGPHSPHVTRGTPINATSSPSAPTLRDSSTRAWEATALSWKDTVPSSNAITPSGSPSIDTPTVTRHTTVSPPTAKATSSAQSPSAMHNVPTALRVTNLPAVSLYPFGAAEGDTECVQRTVDFNSPLLRPEIGFPLGKALRDTLYFTDNGQIIFPPTDSHMPSSPHPPSQGFSSHEALPMVAAFWDDADFSRGVGTTWYQEYPTLGSIQYPIIRDVEAKIQKYLQVPYSAKWTLKVTWEKAPAFPSQLDDTNTYQAVLSTDGSRSFALLLYQDGGMRWDYARLAARDALIGFSSGDGYAQNSELTKEPPAVRYRPDQQRSSGMDVRGLWLFRLDRHSRVNYRLQCLTWLQAQPPPSTWSMELPPCPCSQPQAELDPRYRRSRSADRMGAGVRCVYRGTGLLEGWLERFWNGELEAFEWCCRQVGKPHFCTRYSEKRPRAGCEEYVPPTPANAFGDPHVTTLDGLTYTFNALGDFVLLLASDAHTSFVLQGRMARTGTAQATNFMAFVAQYTSSTTTTVEWTLGSRNEIHVLLNYETIQFSYSQDMGAEVYYSPSVLLVNTSSITAVFNGTISISVSASSGMLSAVCSLLEQYRNGTRGLLGVWNDNPADDFQMPNGTNIPVNSSEEDVFCYGMTCKSELGNQPVRTFNPIFLSQLRQENESQYQLAASQCGGCRECIYDMLSTGDVALGLATQSLVEDFQKRKAALSKWGVGNVEETEQVTRQYRATGPGVRFVPHVSPELNDGMLTWEPRGTAPLSITLQAVSPHLPPALLQLSFTLCSCRSIQQCDYNSTTTIASSSLQVAKCDDGYWGPFCQHEPDPCAQGCFPGVGCDPHTGCGPCPPGLTGDGRHCAGESLGCGTACRSRSCPEGFCSNGGHCHLHPPSCTPTCECPPSVYRPALCGGRRGLPAPGQCRWVLCPTWGLSVPELQHYFSCTLSGYEGYQLDYVGTVGLICISPCKKGYCQHSGRCQHLPEGPTCSCVPFSIFSPGGARCEQLAVSLTAFISIMVGALALLCLLFSIARNGVCAGAVWLFLLNPCPTAPCSVTAPHMGG", "length": 1064, "header": "tr|A0A8V0YK63-1|A0A8V0YK63_CHICK Computationally mapped isoform of Mucin-4 OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0YK80-1" }, "locus": { "chromosome": "9", "start_pos": 14683919, "end_pos": 14675660, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010036580.1", "url": "https://www.ensembl.org/id/ENSGALT00010036580.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021324.1", "url": "https://www.ensembl.org/id/ENSGALP00010021324.1" } ] } }, { "isoform_ac": "A0A8V0YK80-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK80/entry#A0A8V0YK80-1", "sequence": { "sequence": "MVTAVSLPDGVPGGGYSTRTQVSTGVSAAQPSGSTFGWAAERVTSRFGSNPYGPGTATLSPVSHSPTEKGMGTSVPSGSSTTPMKSVGSPRALQSTAGQPTLGTAVPLQEITVTEEHVSAISMLTGGIPTPTGSLSPAVIDVSAAPLVLGTEAPSSATSTANDDNGLGQPHSAVTAEGTPGTAQGTVLSDVQHSTGTSPHSLTWIPAELHTAAVRLSQEVMPGLAEATSPLVTAASVTAGDTEPASTMSDRVTSPTVPATTGSPHHDGIQKSDTTILPGSVSATITPSPATDGVSEATAPGLPAPGTAGDGLHRDTAVTHSRVTSQLHVTTAPALGTSTTAVDVTTASHVPTTPFPALGSAETVSITAEATSGYDVLQTEGTPMELGMGTVPSVVPSVSLRDGSTAGQMMGSAALGLGSSTQASTGSIPSENPTVGVPAATANTESTSMVSALPAPHPSSASTTAHLGTATPNHSHSTAQVTVNTDSSSATNPVAGGAEPGVRRVTPLSPSALDSQRPPISLASVTALSPALSRSAAEQDVSVSPSVFQNSSLAVVASSVTPTVVASITPSASVTAPAMVSPSITPSVSATNPALGTRDASQSMVTTPSFAAPSISLGPHSPHVTRGTPINATSSPSAPTLRDSSTRAWEATALSWKDTVPSSNAITPSGSPSIDTPTVTRHTTVSPPTAKATSSAQSPSAMHNVPTALRVTNRKATSAFAAMSSPSKGTPAASSPTSTAPGLGAQSGPVTAPGTPTYATSRNAVFKPGTELGKSVFFPFPNMKERRGPSALFSQLKGENSLNICSHSRPAPGHALTPGAMSICRHPPTHTIRTSPINALPVSVPAVSLYPFGAAEGDTECVQRTVDFNSPLLRPEIGFPLGKALRDTLYFTDNGQIIFPPTDSHMPSSPHPPSQGFSSHEALPMVAAFWDDADFSRGVGTTWYQEYPTLGSIQYPIIRDVEAKIQKYLQVPYSAKWTLKVTWEKAPAFPSQLDDTNTYQAVLSTDGSRSFALLLYQDGGMRWDYARLAARDALIGFSSGDGYAQNSELTKEPPAVRYRPDQQRSSGMDVRGLWLFRLDRHSRVNYRLQCLTWLQAQPPPSTWSMELPPCPCSQPQADTQPLSAHRWGAGGICATYPCDAHTSFVLQGRMARTGTAQATNFMAFVAQYTSSTTTTVEWTLGSRNEIHVLLNYETIQFSYSQDMGAEVYYSPSVLLVNTSSITAVFNGTISISVSASSGMLSAVCSLLEQYRNGTRGLLGVWNDNPADDFQMPNGTNIPVNSSEEDVFCYGMTWAVGEHSLFAQPLAAPVRTFNPIFLSQLRQENESQYQLAASQCGGCRECIYDMLSTGDVALGLATQSLVEDFQKRKAALSKWGVGNVEETEQVTRQYRATGPGVRFVPHVSPELNDGMLTWEPRGTAPLSITLQAVSPHLPPALLQLSFTLCSCRSIQQCDYNSTTTIASSSLQVAKCDDGYWGPFCQHEPDPCAQGCFPGVGCDPHTGCGPCPPGLTGDGRHCAGESLGCGTACRSRSCPEGFCSNGGHSFTDRHCVVAGGDFQPQANLPQRSVLLWVRALQSVTAEEVNATVCSGGGRAVAWGALALPPQGSTDGLTFAVVAEFTYNSSSFVIRFLNEELTAAITTAFNGRRARRDVGAYLLFALSVPELQHYFSCTLSGYEGYQLDYVGTVGLICISPCKKGYCQHSGRCQHLPEGPTCSCVPFSIFSPGGARCEQLAVSLTAFISIMVGALALLCLLFSIARNGVCAGAVWLFLLNPCPTAPCSVTAPHMGG", "length": 1788, "header": "tr|A0A8V0YK80-1|A0A8V0YK80_CHICK Isoform 1 of Mucin-4 OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0YK80-1" }, "locus": { "chromosome": "9", "start_pos": 14683919, "end_pos": 14673851, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010036602.1", "url": "https://www.ensembl.org/id/ENSGALT00010036602.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021339.1", "url": "https://www.ensembl.org/id/ENSGALP00010021339.1" } ] } }, { "isoform_ac": "A0A8V0YRK0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK80/entry#A0A8V0YRK0-1", "sequence": { "sequence": "MAFGGGGGRRHPWQKLIDELFLSSPINALPVSVPAVSLYPFGAAEGDTECVQRTVDFNSPLLRPEIGFPLGKALRDTLYFTDNGQIIFPPTDSHMPSSPHPPSQGFSSHEALPMVAAFWDDADFSRGVGTTWYQEYPTLGSIQYPIIRDVEAKIQKYLQVPYSAKWTLKVTWEKAPAFPSQLDDTNTYQAVLSTDGSRSFALLLYQDGGMRWDYARLAARDALIGFSSGDGYAQNSELTKEPPAVRYRPDQQRSSGMDVRGLWLFRLDRHSRVNYRLQCLTWLQAQPPPSTWSMELPPCPCSQPQAELDPRYRRSRSADRMGAGVRCVYRGTGLLEGWLERFWNGELEAFEWCCRQVGKPHFCTRYSEKRPRAGCEEYVPPTPANAFGDPHVTTLDGLTYTFNALGDFVLLLASDAHTSFVLQGRMARTGTAQATNFMAFVAQYTSSTTTTVEWTLGSRNEIHVLLNYETIQFSYSQDMGAEVYYSPSVLLVNTSSITAVFNGTISISVSASSGMLSAVCSLLEQYRNGTRGLLGVWNDNPADDFQMPNGTNIPVNSSEEDVFCYGMTCKSELGNQPVRTFNPIFLSQLRQENESQYQLAASQCGGCRECIYDMLSTGDVALGLATQSLVEDFQKRKAALSKWGVGNVEETEQVTRQYRATGPGVRFVPHVSPELNDGMLTWEPRGTAPLSITLQAVSPHLPPALLQLSFTLCSCRSIQQCDYNSTTTIASSSLQVAKCDDGYWGPFCQHEPDPCAQGCFPGVGCDPHTGCGPCPPGLTGDGRHCAGESLGCGTACRSRSCPEGFCSNGGHCHLHPPSCTPTCECPPSVYRPALCGGRRGLPAPGQCRWVLCPTWGLSVPELQHYFSCTLSGYEGYQLDYVGTVGLICISPCKKGYCQHSGRCQHLPEGPTCSCVPFSIFSPGGARCEQLAVSLTAFISIMVGALALLCLLFSIARNGVCAGAVWLFLLNPCPTAPCSVTAPHMGG", "length": 986, "header": "tr|A0A8V0YRK0-1|A0A8V0YRK0_CHICK Computationally mapped isoform of Mucin-4 OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0YK80-1" }, "locus": { "chromosome": "9", "start_pos": 14683919, "end_pos": 14676496, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010036575.1", "url": "https://www.ensembl.org/id/ENSGALT00010036575.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021321.1", "url": "https://www.ensembl.org/id/ENSGALP00010021321.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1713, "start_aa": "Thr", "end_pos": 1713, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1713", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1776, "start_aa": "Thr", "end_pos": 1776, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1776", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 179, "start_aa": "Thr", "end_pos": 179, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr179", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "R-GGA-913709", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-913709", "resource": "Reactome", "description": "O-linked glycosylation of mucins" }, { "id": "R-GGA-977068", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-977068", "resource": "Reactome", "description": "Termination of O-glycan biosynthesis" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YK80", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK80" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YK80", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK80" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "maintenance of gastrointestinal epithelium", "id": "GO:0030277", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030277", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YK80", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK80" } ], "pmid": "" }, { "name": "cell-matrix adhesion", "id": "GO:0007160", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007160", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YK80", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK80" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1217, "end_pos": 1219, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1226, "end_pos": 1228, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1252, "end_pos": 1254, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1273, "end_pos": 1275, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1280, "end_pos": 1282, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1324, "end_pos": 1326, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1455, "end_pos": 1457, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1583, "end_pos": 1585, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1621, "end_pos": 1623, "annotation": "n_glycosylation_sequon" }, { "start_pos": 473, "end_pos": 475, "annotation": "n_glycosylation_sequon" }, { "start_pos": 550, "end_pos": 552, "annotation": "n_glycosylation_sequon" }, { "start_pos": 631, "end_pos": 633, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YK80", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK80" }, { "id": "PS50026", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50026" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "EGF-like", "eco_id": "ECO_0000259", "start_pos": 1691, "end_pos": 1730, "start_aa": "Ile", "end_aa": "Glu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0YK80", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK80" }, { "id": "PS51220", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51220" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "NIDO", "eco_id": "ECO_0000259", "start_pos": 928, "end_pos": 1081, "start_aa": "Ala", "end_aa": "His", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0YK80", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK80" }, { "id": "PS51233", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51233" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "VWFD", "eco_id": "ECO_0000259", "start_pos": 1088, "end_pos": 1303, "start_aa": "Leu", "end_aa": "Gln", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 179, 1713, 1776 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1217, "end_pos": 1219 }, { "start_pos": 1226, "end_pos": 1228 }, { "start_pos": 1252, "end_pos": 1254 }, { "start_pos": 1273, "end_pos": 1275 }, { "start_pos": 1280, "end_pos": 1282 }, { "start_pos": 1324, "end_pos": 1326 }, { "start_pos": 1455, "end_pos": 1457 }, { "start_pos": 1583, "end_pos": 1585 }, { "start_pos": 1621, "end_pos": 1623 }, { "start_pos": 473, "end_pos": 475 }, { "start_pos": 550, "end_pos": 552 }, { "start_pos": 631, "end_pos": 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annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052535.1) annotated using gene prediction method: Gnomon, supported by EST evidence. 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327, "header": "tr|A0A8V0YK92-1|A0A8V0YK92_CHICK Isoform 1 of Ankyrin repeat and SOCS box protein 12 OS=Gallus gallus OX=9031 GN=ASB12 PE=4 SV=1 CANONICAL=A0A8V0YK92-1" }, "locus": { "chromosome": "4", "start_pos": 11617468, "end_pos": 11615370, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032213.1", "url": "https://www.ensembl.org/id/ENSGALT00010032213.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019003.1", "url": "https://www.ensembl.org/id/ENSGALP00010019003.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-8951664", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8951664", "resource": "Reactome", "description": "Neddylation" }, { "id": "R-GGA-983168", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983168", "resource": "Reactome", "description": "Antigen processing: Ubiquitination & Proteasome degradation" 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"A0A8V0YK96-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKA1/entry#A0A8V0YK96-1", "sequence": { "sequence": "MAVPCMELNNKMKMPVLGLGTWQAPPGKVEEVVKHAIDAGYRHIDCAYFYQNEHEIGNAIKQKIKEGAVKREDLFVVTKLWNTFHEKSLVKEGCKRSLTALQLDYVDLYLMHYPMGFKAGEELLPEDDKGMIIPSDTDFLDTWEAMEELVDCGKVKAIGISNFNHEQIERLLNKPGLKYKPVVNQIECHPYLTQEKLIKYCHSKGIAVTAYSPLGSPNRPWAKPGEPMLLEDPKIKEIAARYHKTPAQVRGVDRGSCSSSLVSLQVLPSLDIQYNGVELHLSLCTDPILIGIHMYYHIFSMRS", "length": 303, "header": "tr|A0A8V0YK96-1|A0A8V0YKA1_CHICK Computationally mapped isoform of aldose reductase OS=Gallus gallus OX=9031 GN=AKR1B10 PE=1 SV=1 CANONICAL=A0A8V0YKA1-1" }, "locus": { "chromosome": "1", "start_pos": 62525533, "end_pos": 62519825, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032490.1", "url": "https://www.ensembl.org/id/ENSGALT00010032490.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019234.1", "url": "https://www.ensembl.org/id/ENSGALP00010019234.1" } ] } }, { "isoform_ac": "A0A8V0YKA1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKA1/entry#A0A8V0YKA1-1", "sequence": { "sequence": "MAVPCMELNNKMKMPVLGLGTWQAPPGKVEEVVKHAIDAGYRHIDCAYFYQNEHEIGNAIKQKIKEGAVKREDLFVVTKLWNTFHEKSLVKEGCKRSLTALQLDYVDLYLMHYPMGFKAGEELLPEDDKGMIIPSDTDFLDTWEAMEELVDCGKVKAIGISNFNHEQIERLLNKPGLKYKPVVNQIECHPYLTQEKLIKYCHSKGIAVTAYSPLGSPNRPWAKPGEPMLLEDPKIKEIAARYHKTPAQVLIRFIIQRNLAVIPKSDKQQRIKENMQVFDFELSKKEMDVILSFNRNWRAIPVPQYAPYYLYYPLGLLVSVFSYPVS", "length": 326, "header": "tr|A0A8V0YKA1-1|A0A8V0YKA1_CHICK Isoform 1 of aldose reductase OS=Gallus gallus OX=9031 GN=AKR1B10 PE=1 SV=1 CANONICAL=A0A8V0YKA1-1" }, "locus": { "chromosome": "1", "start_pos": 62525533, "end_pos": 62517604, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032494.1", "url": "https://www.ensembl.org/id/ENSGALT00010032494.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019239.1", "url": "https://www.ensembl.org/id/ENSGALP00010019239.1" } ] } } ], "glycosylation": [], "phosphorylation": [], 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] }, { "id": "15937", "name": "", "equation": "a primary alcohol + NADP(+) = an aldehyde + NADPH + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q5ZK84-1", "A0A8V1A5L2-1", "Q9PWR1-1", "A0A8V0YKA1-1" ], "evidence": [ { "id": "15937", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/15937" } ] }, { "id": "45312", "name": "", "equation": "prostaglandin F2alpha + NADP(+) = prostaglandin H2 + NADPH + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1BVD1-1", "A0A8V0YKB8-1", "A0A8V0YJV4-1", "A0A8V0YKA1-1" ], "evidence": [ { "id": "45312", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/45312" } ] }, { "id": "63500", "name": "", "equation": "S-nitrosoglutathione + NADPH + H(+) = S-(hydroxysulfenamide)glutathione + NADP(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": 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The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
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The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. 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"MEVQDGGQEMVASPATPGSGKSKLDTLPKEDLIKFAKKQMMLIQKVKSRCTELEREIEELRSKPATGGADDIIQALTERLDVVLLEKAESQQQCVALKKENLQRKQEAEAAVARTEELQKQLEQSNTDSLEEIKALKNELINAQSKYNEDLTKLKTELEEKEKKQMELVEQIKCCSDNQEEVKRLQDYVQKIKSTYEDQILCLNKQLETVNDDKNKEIATLQETIRSNSQCYHNEISSLSEELKQLKIAHQEEVSELMHHIEISSKENEEKQNQINQLQHSLAEADLIKEKNVKDEAYGHTEQHKHDFEQLKQVLNKNIEDKVNVLDMQEEPCVEAKMEEKIRHLECSLGDLQSQHSILKDELTYMSNVKLKLEEEIHRIKDEYFHEREDLDFKINELQLIKEDYCCVIEKLKLELQTARHHYETTAEEHKLETQNLREQHEREISELNKTLLSSSEKEKMALVLEMQELKDQLEKLTLEKEDAVLSYDSLRETLETIQTELGESAGKISQQFESMKQQQASDVSELQQKLRAAFNEKDGLLETVNRLQAETQKLSSYQLEIEELKHKIVSLQEENDTITSCVHQKEASIKELEEKTIALANQNKDILNEVKCSGEEREALQERCKQEQGKVQELQQEVDVVNQYNSDLKKKLEELTERLNDALTGKNENTKMLEQLENQIDTLVRERENLSSEVSALREENKKIVQEKEELSKELEKITYEKDGWLVLKEQFENLEKKLQMVTAEKDHISSLLESEQVHKSLVRTQLYHILEQVGYSISDSNEECDFLNLLQIANEHLIKMKEKQCFALQNEEKVLHLQREIERLEEENATQYTEHRSLIQDFGREKDHLKEELEEVLSEKEALQHDIQELRSAGEKATIENQDLLAKIEEMSEKLAFYESQIQEQQKGSKAQEELNFILEQKETELRNVKDELSSLKTVMESLTGKNDEQSSVAELQEKIERLEKESAEKGEKLNKMKAVAVRAKKELDTSRKEMQALREELEVVRSEKDQLSASMKDVIQGAESYKNLLMEYDKQGEELDSEKGRANSLERQIDDLTRQLQVSSQQHDQLHSANEDLLARVETLQCNSKLLEAQILELQKVKAKAEKELEAEKLLKEQKMKEHSGTVRELEELQMQLQKEKKYLQKIMQELELAKKDAQKSTLMDMEIADYEKLVKELNQKITDKDSRIEDLEQETGIQKQKQETLQEEIKSLQSTMQEDEERNAKIKQLLVKTKKELADSKRAENDHLMLQASLKGELEASQQQVEAFKIQVAALTSEKHKVQEHLRTSSEQHQRTLNAYQQKIATLREECRAAQAEQASVTSEFESYKVRVHNVLKQQKNKTASQTETEGAKQEREQLETVIEQLKAKLQETQHNLQINAAEFQALQSEHDTLLERHNKMLQETVAKEAELREKFCTIQSENMVMKTEHAQALSQLTAQNEALRNNFRDQVRNLQEEHRKTVETLQQQLSRVEAQLFQLKSEPSTRGPAVSNPVPKNLRERRNTDLPVLDVHAIAREEGEGMETTDTESVSSASTYIPSLEQLLNSPETKPETSQWQTELTKDELIEKLSTTTKSADHLNELLRESEATNAILMEQIKLLKSEIRRLERNQEREKSVANLEYLKNVLLQFIFLKSGSERERLLPVIDTMLQLSPEEKGKLVAIAQGPKYTRSTLSMQDTEAVRTLAFTIPLVFHCASLTLSYISSFLTASASEVK", "length": 1720, "header": "tr|A0A8V0YKB0-1|A0A8V0YKB0_CHICK Isoform 1 of GRIP and coiled-coil domain containing 2 OS=Gallus gallus OX=9031 GN=GCC2 PE=1 SV=1 CANONICAL=A0A8V0YKB0-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YKB0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKB0/entry#A0A8V0YKB0-1", "sequence": { "sequence": "MEVQDGGQEMVASPATPGSGKSKLDTLPKEDLIKFAKKQMMLIQKVKSRCTELEREIEELRSKPATGGADDIIQALTERLDVVLLEKAESQQQCVALKKENLQRKQEAEAAVARTEELQKQLEQSNTDSLEEIKALKNELINAQSKYNEDLTKLKTELEEKEKKQMELVEQIKCCSDNQEEVKRLQDYVQKIKSTYEDQILCLNKQLETVNDDKNKEIATLQETIRSNSQCYHNEISSLSEELKQLKIAHQEEVSELMHHIEISSKENEEKQNQINQLQHSLAEADLIKEKNVKDEAYGHTEQHKHDFEQLKQVLNKNIEDKVNVLDMQEEPCVEAKMEEKIRHLECSLGDLQSQHSILKDELTYMSNVKLKLEEEIHRIKDEYFHEREDLDFKINELQLIKEDYCCVIEKLKLELQTARHHYETTAEEHKLETQNLREQHEREISELNKTLLSSSEKEKMALVLEMQELKDQLEKLTLEKEDAVLSYDSLRETLETIQTELGESAGKISQQFESMKQQQASDVSELQQKLRAAFNEKDGLLETVNRLQAETQKLSSYQLEIEELKHKIVSLQEENDTITSCVHQKEASIKELEEKTIALANQNKDILNEVKCSGEEREALQERCKQEQGKVQELQQEVDVVNQYNSDLKKKLEELTERLNDALTGKNENTKMLEQLENQIDTLVRERENLSSEVSALREENKKIVQEKEELSKELEKITYEKDGWLVLKEQFENLEKKLQMVTAEKDHISSLLESEQVHKSLVRTQLYHILEQVGYSISDSNEECDFLNLLQIANEHLIKMKEKQCFALQNEEKVLHLQREIERLEEENATQYTEHRSLIQDFGREKDHLKEELEEVLSEKEALQHDIQELRSAGEKATIENQDLLAKIEEMSEKLAFYESQIQEQQKGSKAQEELNFILEQKETELRNVKDELSSLKTVMESLTGKNDEQSSVAELQEKIERLEKESAEKGEKLNKMKAVAVRAKKELDTSRKEMQALREELEVVRSEKDQLSASMKDVIQGAESYKNLLMEYDKQGEELDSEKGRANSLERQIDDLTRQLQVSSQQHDQLHSANEDLLARVETLQCNSKLLEAQILELQKVKAKAEKELEAEKLLKEQKMKEHSGTVRELEELQMQLQKEKKYLQKIMQELELAKKDAQKSTLMDMEIADYEKLVKELNQKITDKDSRIEDLEQETGIQKQKQETLQEEIKSLQSTMQEDEERNAKIKQLLVKTKKELADSKRAENDHLMLQASLKGELEASQQQVEAFKIQVAALTSEKHKVQEHLRTSSEQHQRTLNAYQQKIATLREECRAAQAEQASVTSEFESYKVRVHNVLKQQKNKTASQTETEGAKQEREQLETVIEQLKAKLQETQHNLQINAAEFQALQSEHDTLLERHNKMLQETVAKEAELREKFCTIQSENMVMKTEHAQALSQLTAQNEALRNNFRDQVRNLQEEHRKTVETLQQQLSRVEAQLFQLKSEPSTRGPAVSNPVPKNLRERRNTDLPVLDVHAIAREEGEGMETTDTESVSSASTYIPSLEQLLNSPETKPETSQWQTELTKDELIEKLSTTTKSADHLNELLRESEATNAILMEQIKLLKSEIRRLERNQEREKSVANLEYLKNVLLQFIFLKSGSERERLLPVIDTMLQLSPEEKGKLVAIAQGPKYTRSTLSMQDTEAVRTLAFTIPLVFHCASLTLSYISSFLTASASEVK", "length": 1720, "header": "tr|A0A8V0YKB0-1|A0A8V0YKB0_CHICK Isoform 1 of GRIP and coiled-coil domain containing 2 OS=Gallus gallus OX=9031 GN=GCC2 PE=1 SV=1 CANONICAL=A0A8V0YKB0-1" }, "locus": { "chromosome": "1", "start_pos": 136323925, "end_pos": 136294537, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010036641.1", "url": "https://www.ensembl.org/id/ENSGALT00010036641.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021372.1", "url": "https://www.ensembl.org/id/ENSGALP00010021372.1" } ] } }, { "isoform_ac": "A0A8V0YYG0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKB0/entry#A0A8V0YYG0-1", "sequence": { "sequence": "MEVQDGGQEMVASPATPGSGKSKLDTLPKEDLIKFAKKQMMLIQKVKSRCTELEREIEELRSKPATGGADDIIQALTERLDVVLLEKAESQQQCVALKKENLQRKQEAEAAVARTEELQKQLEQSNTDSLEEIKALKNELINAQSKYNEDLTKLKTELEEKEKKQMELVEQIKCCSDNQEEVKRLQDYVQKIKSTYEDQILCLNKQLETVNDDKNKEIATLQETIRSNSQCYHNEISSLSEELKQLKIAHQEEVSELMHHIEISSKENEEKQNQINQLQHSLAEADLIKEKNVKDEAYGHTEQHKHDFEQLKQVLNKNIEDKVNVLDMQEEPCVEAKMEEKIRHLECSLGDLQSQHSILKDELTYMSNVKLKLEEEIHRIKDEYFHEREDLDFKINELQLIKEDYCCVIEKLKLELQTARHHYETTAEEHKLETQNLREQHEREISELNKTLLSSSEKEKMALVLEMQELKDQLEKLTLEKEDAVLSYDSLRETLETIQTELGESAGKISQQFESMKQQQASDVSELQQKLRAAFNEKDGLLETVNRLQAETQKLSSYQLEIEELKHKIVSLQEENDTITSCVHQKEASIKELEEKTIALANQNKDILNEVKCSGEEREALQERCKQEQGKVQELQQEVDVVNQYNSDLKKKLEELTERLNDALTGKNENTKMLEQLENQIDTLVRERENLSSEVSALREENKKIVQEKEELSKELEKITYEKDGWLVLKEQFENLEKKLQMVTAEKDHISSLLESEQVHKSLVRTQLYHILEQVGYSISDSNEECDFLNLLQIANEHLIKMKEKQCFALQNEEKVLHLQREIERLEEENATQYTEHRSLIQDFGREKDHLKEELEEVLSEKEALQHDIQELRSAGEKATIENQDLLAKIEEMSEKLAFYESQIQEQQKGSKAQEELNFILEQKETELRNVKDELSSLKTVMESLTGKNDEQSSVAELQEKIERLEKESAEKGEKLNKMKAVAVRAKKELDTSRKEMQALREELEVVRSEKDQLSASMKDVIQGAESYKNLLMEYDKQGEELDSEKGRANSLERQIDDLTRQLQVSSQQHDQLHSANEDLLARVETLQCNSKLLEAQILELQKVKAKAEKELEAEKLLKEQKMKEHSGTVRELEELQMQLQKEKKYLQKIMQELELAKKDAQKSTLMDMEIADYEKLVKELNQKITDKDSRIEDLEQETGIQKQKQETLQEEIKSLQSTMQEDEERNAKIKQLLVKTKKELADSKRAENDHLMLQASLKGELEASQQQVEAFKIQVAALTSEKHKVQEHLRTSSEQHQRTLNAYQQKIATLREECRAAQAEQASVTSEFESYKVRVHNVLKQQKNKTASQTETEGAKQEREQLETVIEQLKAKLQETQHNLQINAAEFQALQSEHDTLLERHNKMLQETVAKEAELREKFCTIQSENMVMKTEHAQALSQLTAQNEALRNNFRDQVRNLQEEHRKTVETLQQQLSRVEAQLFQLKSEPSTRGPAVSNPVPKNLRERRNTDLPVLDVHAIAREEGEGMETTDTESVSSASTYIPSLEQLLNSPETKPETSQWQTELTKDELIEKLSTTTKSADHLNELLRESEATNAILMEQIKLLKSEIRRLERNQEREKSVANLEYLKNVLLQFIFLKSGSERERLLPVIDTMLQLSPEEKGKLVAIAQGEEESSSRPSGWASYLHSWSGLR", "length": 1693, "header": "tr|A0A8V0YYG0-1|A0A8V0YYG0_CHICK Computationally mapped isoform of GRIP and coiled-coil domain containing 2 OS=Gallus gallus OX=9031 GN=GCC2 PE=1 SV=1 CANONICAL=A0A8V0YKB0-1" }, "locus": { "chromosome": "1", "start_pos": 136319493, "end_pos": 136294537, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010036636.1", "url": "https://www.ensembl.org/id/ENSGALT00010036636.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021368.1", "url": "https://www.ensembl.org/id/ENSGALP00010021368.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 16, "start_aa": "Thr", "end_pos": 16, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr16", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:428014", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:428014", "resource": "KEGG Pathway" }, { "id": "R-GGA-6811440", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6811440", "resource": "Reactome", "description": "Retrograde transport at the Trans-Golgi-Network" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZZL9-1", "protein_name": "GRIP and coiled-coil domain-containing protein 2", "gene_name": "Gcc2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEDSAQDAVTAAPSGTPKSKLETLPREDLIKFAKKQMMLLQKAKARCTELDKEVEELKSKPVDGGTDDMIKVLTERLDALLLEKAETEQQCLCLKKENIKMKQEVEDSVTKLEETQKEFEQSHRNYVREMESVKNELIAVHSEHSKEKAALQRDLEGAVHRQAELLEQLKSQSDSEDNVKKLQEEIQNITAAFEEQTSCLQKQLEATSDEKQQEIIHLQKVIEDNAQHYQKDINTFQEEIVQLRATHKEEVNELMSQMETLAKEHEAAVNKLKENRVTLCETSETIPENYQCESESLNEDTSDASQENQKCSVALQEDPFAEHTVYDKVRQLEDSLKELESQHSILKDEVTYMNNLKLKLEMDAQHIKDEFFHEREDLEFKINELLLAKEEQSYVVEKLKYEREDLNRQLCCTVEQHNKEIQRLQEHHQKEISELSETFMSGSEKEKLALMFEIQGLKEQCENLQHEKQEVVLNYESLREMMEILQTELGESAGKISQEFETMKQQQASDVHELQQKLRTAFNEKDALLETINRLQGENEKLLSQELVSELESTMKNLKADNSMYLASLGQKDTLLQELEAKISSLAEEKDDFISKIKTSREEIDDLHQKWEREQKLSVELREAAEQAAQHNSELRQRVSELTGKLDEILREKSQNDQNIMVQMKTMTEDQEALSSKIKSLYEENNRLHSEKVQLSRDLEALQSQQDFAYKEHVAEFEKKLQLMVEERDDLNKLLENEQLQKSFVKTQLYEFLKQMRPSILEDNEEEDVVTVLKAVGESLVTVKEEKHNLVFEYDARVLELERRIKCLQEESVVQCEELRALVRDSEQEKILLRKELDEVTSTKEALQCDILEMKNTNEKTSLENQTLSTRVEELSRSLHSKNEVHNEKDLVIEHENLRLSLEQRESELQDVRAELMLLKDSLEKSPSVKNDQLSLVKELEEKIESLEKESKDKDEKISKIKLVAVRAKKELDSNRKEAQTLRDELESVQSEKDRLSASMKEFIQGAESYKNLLLEYDKQSEQLDVEKERANNFEHHIEDLTKQLRDSTCQYEKLTSDNEDLLARIETLQANARLLEAQILEVQRAKGVVEKELEAEKLQKEQKIKEHVSTTNELEELQLQFQKEKKQLQKTMQELELVKKDAQQTTLMNMEIADYERLMKELNQKLTNKNSKIEDLEQEMKIQKQKQETLQEEMTSLQSSVQHYEEKNAQIKQLLVKTKKELADAKQAETDHLLLQASLKGELEASQQQVEVYKIQLAEMTSEKHKIHEHLKTSAEQHQRTLSAYQQRVVALQEESRTAKAEQAAVTSEFENYKVRVHNVLKQQKNKSVSQAETEGAKQEREHLEMLIDQLKIKLQDSQNSLQISVSEFQTLQSEHDTLLERHNRMLQETVTKEAELREKLCSAQSENTMLKSEHAQTMCQLTSQNEALRNSFRDQVRHLQDEHRKTVETLQHQLSKVETQLFQLKSEPPTKSPASSHQPSKSLRERRTTDLPLLDMHTVTREEGEGMETTDSESVSSAGTHIQSLEQLLSSPDSKLERLTEASLWHTEFTKEELAEKLSSTTKSADHLNGLLRETEATNAILMEQIKLLKSEIRRLERNQEREKSVANLEYLKNVLLRFIFLKPGSERERLLPVIDTMLQLSPEEKGKLATVAQGEEESASRSSGWASYLHSWSGLR", "length": 1679 }, "evidence": [ { "id": "A0A8V0YKB0", "url": "https://omabrowser.org/oma/group/A0A8V0YKB0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E1BB16-1", "protein_name": "GRIP and coiled-coil domain containing 2", "gene_name": "GCC2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MEEPVHEGVASPAARGTGKSKLEALPKEDLIKFAKKQMMLIQKTKLRCTELEKEVEELKSKLVAGGADIIKALTERLDAVLLEKAETEQHCVSLKKENIKMKQEVEDSVTKLEDVQKELEQSQRSYGKEIENLRNELTTVHSKYSNDKADWQKEVEEAAKKQLELSEQLRFQSDSEDSVKKLQEEIQKIKLAFEDQILCLQKQLETATNEKEQEITHLQGVIEANCQQYQKDINSLQEELVRLKSTHQEEVKELMCQIETSAKEHEAEVNYLIQLKDNLVRKCEAGEMNIQKYKCELENEGKASGAGQENQVCSLLLQEDSLVEQAVNEKVRHLEDALKELESQHSILKDELTYMNNLKLKLEIDAQHIKDEFFHEREDLEFKINELLLAKEEQGYIIEKLKSELEDANKQFCCTIEQHNKEVQSLKKQHQKEITELNETFLSDSEKEKLTLMFEIQGLKEQCEKLQQEKQEAMLNYEGLREIMEILQTELGESAEKISQEFESMKQQQAFNINELQQKLQTAFNEKDALLETVNYLQKENDNLLSQQECVPELENTIKNLQEKNELYLVSLSQRDTMLQEFEAKISSLTEEKYDFISKMRSSHEEMDNLHKKCEREERLTVELREKVDQTAQYNSELEQKVNELTAGLEETLKEKDEKNRKLEKLTAQLKILSKDQEATSLEVRSLREENSRLSSEKNLLSRDLEALLSQKEGDVTFQEQINKLEEELRLAVRERDNLNKLLENEQVQKLFVKAQLCGFLEQMESKVSQEREEQDVVNILQAMGKSLDKINEEKHNLAFQYDKRIVELEEEIKLLQEEHMVQCEELRSLLTDYEQKKIVLRKELEEALLEKEALQSDLLEMKNASEQTRFENQNLLIQVEEMSQKLCRENENHHKKEKDLIKELENLRPLLEQKESELQDVKAELISLKDSFKKSTSVESDQPSVKEFEEKIGYLEKEAKEKEEKINKLKLVAVKAKKELDSSRKEAQTLQEELQSVRSERDQLSTSMRDLIQGAENYKNLLSEYDKQSEQLDAEKERANNFEHQVEDLTRQLRNLTFQCEKLTSDNEDFLARIETLQSNACLLEAQILEVHKAKAMADKELEAEKLQKEQKIKEHASSVNELEELQLQLQKEKKQLQKTMQELELVRKDAQQTTLMNMEIADYERLMRELNQKLSNKNSKIEDLEQEIKIQKQKQETLQEEMTSLQAVLQQYEEKNTKIKQLLVKTKKELADLRQAETDHLMLQASLKGELEASQQQVEVYKIQLAEVTAEKHKAHEHLKASADQHQRTLGAYQQRVSALQEECREARAEQAAVTSEFESYKVRVHNVLKQQKNKSVSQTEAEGAKQEREHLEMLIDQLKLKLQDTQNSLQISTSELQALQCEHCALLERHNRVLQEAVGKEAELREKLCSVQSENSALKAEHAQIVDQLTAQHEALRAGFREQVRQLQEEHRRTVETLQQQLCRLEAQLLEPRSEPATRSPASSQQPLRSLRERRSADLPFLDVQVTAREEGEGMETTDLEHGSPASTPAQSLEQLLSSPEARLEPPAWHNEFTKEELVQKLNSTTKSADHLNGLLRETEATNAILMEQIKLLKSEVRRLERNQEREKSAANLEYLKNVLLQFILLKPGSERARLLPVVDTMLQLSPEEKTRLAAAAQGEEESGSRSSGWASYLHSWSGLR", "length": 1684 }, "evidence": [ { "id": "A0A8V0YKB0", "url": "https://omabrowser.org/oma/group/A0A8V0YKB0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "G3HJ09-1", "protein_name": "GRIP and coiled-coil domain-containing protein 2", "gene_name": "Gcc2", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MEDPVQDGVAAAPSGTGKSKLETLPREDLIKFAKKQMMLLQKAKARCTELDKEIEELKSKPVDGGTDDIIKVLTERLDTLLLDKAETEQQCLCLKKENIKMKQEVEDSVTKLEDTHKEFEQSQRNYVNEIESLKNELMAVQSEHSKEKASLQQELEEAANKQLELLEQLKSQSDSEDRVKQLQEEIHNITARFEEQVLCLQKQLEATNDEKKQEIIHLQKVIEENTRQYQKDIDTFQEEILQLRAAHKEEVNELMSQMEILAKEHEAEINKLKDNRVQQCEGSENNQEKYHCELENLNEGTSDSKQENQHHSLPLQEDTFAEQTVNDKVRQLEDSLKELESQHSILKDEVTYMNNLKLKLEMEAQHIKDEFFHEREDLEFKINELLLAKEEQGYIVEKLKYEQEDLNRQLCCAVEQHNKEIQHLREVHQKEISELSETFMSGSEKEKLALMFEIQGLKEQCENLHHEKQEAILNYESLREMMEILQTELGESAGKISQEFETMKQQQASDVHELQQKLRTAFNEKDALLETVNCLQRENKKLLSHQELVPELESTIKSLKADNSMYLASLGQKDTVLQELEAKISSLAEEKDEFVSKMKTCHAEIDNLHQKWEREQRLTIELREAAEQTTQHNSELRQRVDELTGKLDEILRERSQNDQSIMVQIKTMTEDQEALSSKIQSLYEENDKLLTEKVQLSRDLETLQSQKDFAHKEHVTELEEKLQLMVEERDNLNKVFENEQVQKSFVKTQLYGYLKQMGPNILEENEEEDVVKVLQAVGESLAKIKEEKHNLVFEYDERVLELERKIKCLQEESVAQHEELTALLKDSEQEKILLRKELEETTSSKETLQLDLLEMKNANEKTSLENQTLLAQVEELFQTLHSQNEVRNEKLLVIEHENLKLLLEQRESELQDLRAELIQLKDSLEKSPSVKNDQLSLVKELEEKIGSLEKESKDKDEKISKIKLVAVKAKKELDSNKKEAQTLREELESVRSEKDRLSASMKEFIQGAENYKNLLLEYDKQSEQLDVEKERANNFEHHIEDLTKQLRNSTCQCEKLNSDNEDLLARIETLQSNAKLLEAQILEVQKAKGIVDKELEAEKLQKEQKIKEHVSTVNELEGLQLQFEKEKKQLQKTMQELELVKKDAQQTTLMNMEIADYERLMKELNQKLTNKNSKIEDLEQEIKIQKQKQENLQEEMTSLQTSVQHSEEKNTKIKQLLVKTKKELADSKQAEADHLLLQASLKGELEASQQQVEVYKIQLAEITSEKHKIHEHLKTSAEQHQRTLSAYQQRVAALQEESRTAKAEQAAVTSEFESYKVRVHNVLKQQKNKSVSQAETEGAKQEREHLEMLIDQLKIKLQDSQNSLQINVSELQTLQSEHDTLLERHNRMLQETVTKEAELREKLCSVQSENTVMKSEHAQTVCQLTAQNEALRNSFRDQVRHLQDEHRKTVETLQHQLSKVEAQLFQLKSEPSTRSPASSHQPLKNPRERRNTDLPLLDMHTVAREEGEGMETTDSESVSSAGTHIPSLEQLLSSPDTKLEQHLAEPSLWHAEFTKEELAEKLSSTTKSADHLNGLLRETEATNAILMEQIKLLKSEIRRLERNQEREKSVANLEYLKNVLLRFIFLKPGSERERLLPVIDTMLQLSPEEKGKLATVAQGEEESASRSSGWASYLHSWSGLR", "length": 1681 }, "evidence": [ { "id": "A0A8V0YKB0", "url": "https://omabrowser.org/oma/group/A0A8V0YKB0/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q8CHG3-1", "protein_name": "GRIP and coiled-coil domain-containing protein 2", "gene_name": "Gcc2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEDSAPDAVAAAPSGTPKSKLETLPREDLIKFAKKQMMLLQKAKARCTELDKEVEELKSKPVDGGTDDIIKVLTERLDALLLEKAETEQQCLCLKKENVKMKQEVEDSVTKLEETHKEFEQSHRNYVKEIESCKNELMAVHSEHSKETAILQKELEEAVHKQVELREQLKSQSDSEDNVRKLQEEIQNITAAFEEQISCLEKKLEATSDEKQQEIIHLQKVIEDKAQHYQKDINTFQAEILQLRATHKEEVTELMSQIETSAKEHEAEINKLKENRVTQCEASENIPEKYQCESENLNEVASDASPESQNCSVALQEDPSAEQTVCDKVRQLEDSLKELESQHSILKDEVTYMNNLKLKLEMDAQHIKDEFFHEREDLEFKINELLLAKEEQGYVVEKLKYEREDLNRQLCCAVEQHNKEIQRLQEHHQKEVSELSETFISGSEKEKLALMFEIQGLKEQCENLQHEKQEVVLNYESLREMMEILQTELGESAGKISQEFETMKQQQASDVHELQQKLRSAFNEKDALLETVNRLQGENEKLLSQQELVPELESTIKNLQADNSMYLASLGQKDTMLQELEAKISSLAKEKDDFISKIKTSHEEMDDLHQKWEREQRLSVELREAAGQAAQHNSELRQRVSELTGKLDELVREKSQNDQSITVQMKTMTEDQEALSSKIKSLYEENNRLHSEKAQLSRDLEALQAQQDFAHKEHVAEFEKKLQLMVEERDDLNKLLENEQVQKSFVKTQLYEYLKQLRASILEENEEEDVVKLIQAVGESLVKVKEEEHNLVFEYDARVLELENKIKCLQEDSAVQCEELRTLVRDSEQEKILLRKELDAVTSAKEALQLDLLEMKNTNEKASLENQTLSTQVEELSQTLHSRNEVHDEKVLVIEHENLRLLLKQRESELQDVRAELILLKDSLEKSPSVKNDQLSLVKELEEKIESLEKESKDKDEKISKIKLVAVKAKKELDSNRKEAQTLREELESVRSEKDRLSASMKEFLQGAESYKSLLLEYDKQSEQLDVEKERAHNFERHIEDLTKQLRNSTCQYERLTSDNEDLLARIETLQANAKLLEAQILEVQKAKGVVEKELDAEKLQKEQKIKEHVSTVNELEELQLQFQKEKKQLQKTMQELELVKKDAQQTTLMNMEIADYERLMKELNQKLTNKNSTIEDLEQEMKIQKEKQETLQEEITSLQSSVQHYEEKNTKIKQLLVKTKKELADAKQAETDHLLLQASLKGELEASQQQVEVYKIQLAEMTSEKHKIHEHLKTSAEQHQRTLSAYQQRVVALQEESRAAKAEQAAVTSEFESYKVRVHNVLKQQKNKSVSQVETEGAKQEREHLEMLIDQLKIKLQDSQNSLQISVSEYQTLQAEHDTLLERHNRMLQETVTKEAELREKLCSVQSENTMMKSEHSQTMCQLTSQNEALRTSFRDQVRHLQDEHRKTVETLQHQLSKLEAQLFQLKSEPSTRSPASSHQPSKSLRERRTTDLPLLDMHTVAREEGEGMETTDSESVSSAGTHIQSLEQLLSSPDTKLERLAETSLWHNEFTKEELAEKLSSTTKSADHLNGLLRETEATNAILMEQIKLLKSEIRRLERNQEREKSVANLEYLKNVLLRFIFLKPGSERERLLPVIDTMLQLSPEEKGKLATVAQGEEESASRSSGWASYLHSWSGLR", "length": 1680 }, "evidence": [ { "id": "A0A8V0YKB0", "url": "https://omabrowser.org/oma/group/A0A8V0YKB0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8IWJ2-1", "protein_name": "GRIP and coiled-coil domain-containing protein 2", "gene_name": "GCC2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEDLVQDGVASPATPGTGKSKLETLPKEDLIKFAKKQMMLIQKAKSRCTELEKEIEELRSKPVTEGTGDIIKALTERLDALLLEKAETEQQCLSLKKENIKMKQEVEDSVTKMGDAHKELEQSHINYVKEIENLKNELMAVRSKYSEDKANLQKQLEEAMNTQLELSEQLKFQNNSEDNVKKLQEEIEKIRPGFEEQILYLQKQLDATTDEKKETVTQLQNIIEANSQHYQKNINSLQEELLQLKAIHQEEVKELMCQIEASAKEHEAEINKLNELKENLVKQCEASEKNIQKKYECELENLRKATSNANQDNQICSILLQENTFVEQVVNEKVKHLEDTLKELESQHSILKDEVTYMNNLKLKLEMDAQHIKDEFFHEREDLEFKINELLLAKEEQGCVIEKLKSELAGLNKQFCYTVEQHNREVQSLKEQHQKEISELNETFLSDSEKEKLTLMFEIQGLKEQCENLQQEKQEAILNYESLREIMEILQTELGESAGKISQEFESMKQQQASDVHELQQKLRTAFTEKDALLETVNRLQGENEKLLSQQELVPELENTIKNLQEKNGVYLLSLSQRDTMLKELEGKINSLTEEKDDFINKLKNSHEEMDNFHKKCEREERLILELGKKVEQTIQYNSELEQKVNELTGGLEETLKEKDQNDQKLEKLMVQMKVLSEDKEVLSAEVKSLYEENNKLSSEKKQLSRDLEVFLSQKEDVILKEHITQLEKKLQLMVEEQDNLNKLLENEQVQKLFVKTQLYGFLKEMGSEVSEDSEEKDVVNVLQAVGESLAKINEEKCNLAFQRDEKVLELEKEIKCLQEESVVQCEELKSLLRDYEQEKVLLRKELEEIQSEKEALQSDLLEMKNANEKTRLENQNLLIQVEEVSQTCSKSEIHNEKEKCFIKEHENLKPLLEQKELRDRRAELILLKDSLAKSPSVKNDPLSSVKELEEKIENLEKECKEKEEKINKIKLVAVKAKKELDSSRKETQTVKEELESLRSEKDQLSASMRDLIQGAESYKNLLLEYEKQSEQLDVEKERANNFEHRIEDLTRQLRNSTLQCETINSDNEDLLARIETLQSNAKLLEVQILEVQRAKAMVDKELEAEKLQKEQKIKEHATTVNELEELQVQLQKQKKQLQKTMQELELVKKDAQQTTLMNMEIADYERLMKELNQKLTNKNNKIEDLEQEIKIQKQKQETLQEEITSLQSSVQQYEEKNTKIKQLLVKTKKELADSKQAETDHLILQASLKGELEASQQQVEVYKIQLAEITSEKHKIHEHLKTSAEQHQRTLSAYQQRVTALQEECRAAKAEQATVTSEFESYKVRVHNVLKQQKNKSMSQAETEGAKQEREHLEMLIDQLKIKLQDSQNNLQINVSELQTLQSEHDTLLERHNKMLQETVSKEAELREKLCSIQSENMMMKSEHTQTVSQLTSQNEVLRNSFRDQVRHLQEEHRKTVETLQQQLSKMEAQLFQLKNEPTTRSPVSSQQSLKNLRERRNTDLPLLDMHTVTREEGEGMETTDTESVSSASTYTQSLEQLLNSPETKLEPPLWHAEFTKEELVQKLSSTTKSADHLNGLLRETEATNAILMEQIKLLKSEIRRLERNQEREKSAANLEYLKNVLLQFIFLKPGSERERLLPVINTMLQLSPEEKGKLAAVAQGEEENASRSSGWASYLHSWSGLR", "length": 1684 }, "evidence": [ { "id": "A0A8V0YKB0", "url": "https://omabrowser.org/oma/group/A0A8V0YKB0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKB0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKB0" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKB0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKB0" } ], "pmid": "" }, { "name": "trans-Golgi network", "id": "GO:0005802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005802", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKB0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKB0" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKB0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKB0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKB0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKB0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 8, "go_terms": [ { "name": "protein targeting to lysosome", "id": "GO:0006622", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006622", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKB0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKB0" } ], "pmid": "" }, { "name": "Golgi ribbon formation", "id": "GO:0090161", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090161", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKB0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKB0" } ], "pmid": "" }, { "name": "protein localization to Golgi apparatus", "id": "GO:0034067", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034067", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKB0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKB0" } ], "pmid": "" }, { "name": "microtubule anchoring", "id": "GO:0034453", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034453", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKB0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKB0" } ], "pmid": "" }, { "name": "microtubule organizing center organization", "id": "GO:0031023", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031023", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKB0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKB0" } ], "pmid": "" }, { "name": "late endosome to Golgi transport", "id": "GO:0034499", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034499", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKB0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKB0" } ], "pmid": "" }, { "name": "regulation of protein exit from endoplasmic reticulum", "id": "GO:0070861", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070861", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKB0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKB0" } ], "pmid": "" }, { "name": "recycling endosome to Golgi transport", "id": "GO:0071955", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071955", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKB0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKB0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1345, "end_pos": 1347, "annotation": "n_glycosylation_sequon" }, { "start_pos": 449, "end_pos": 451, "annotation": "n_glycosylation_sequon" }, { "start_pos": 576, "end_pos": 578, "annotation": "n_glycosylation_sequon" }, { "start_pos": 690, "end_pos": 692, "annotation": "n_glycosylation_sequon" }, { "start_pos": 830, "end_pos": 832, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YKB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKB0" }, { "id": "PS50913", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50913" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "GRIP", "eco_id": "ECO_0000259", "start_pos": 1618, "end_pos": 1668, "start_aa": "Arg", "end_aa": "Ile", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 16 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1345, "end_pos": 1347 }, { "start_pos": 449, "end_pos": 451 }, { "start_pos": 576, "end_pos": 578 }, { "start_pos": 690, "end_pos": 692 }, { "start_pos": 830, "end_pos": 832 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YKB4-1", "uniprot_ac": "A0A8V0YKB4", "uniprot_id": "A0A8V0YKB4_CHICK", "mass": { "chemical_mass": 41410.0, "monoisotopic_mass": 41410.0 }, "refseq": { "ac": "XP_046791757", "name": "guanine nucleotide-binding protein subunit alpha-14 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046791757" }, "gene_names": [ { "name": "GNA14", "type": "recommended", "evidence": [ { "id": "A0A8V0YKB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKB4" } ] }, { "name": "GNA14", "type": "synonym", "evidence": [ { "id": "XP_046791757", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046791757" } ] } ], "protein_names": [ { "name": "Guanine nucleotide-binding protein subunit alpha", "type": "recommended", "evidence": [ { "id": "A0A8V0YKB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKB4/entry#names_and_taxonomy" } ] }, { "name": "guanine nucleotide-binding protein subunit alpha-14 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_046791757", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046791757" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_059536) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_046791757", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046791757" } ] }, { "annotation": "Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKB4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKB4#function" }, { "database": "UniProtKB", "id": "RU369122", "url": "https://www.uniprot.org/uniprotkb/RU369122#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKB4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKB4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": 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"A0A8V0YKC1-1", "uniprot_ac": "A0A8V0YKC1", "uniprot_id": "A0A8V0YKC1_CHICK", "mass": { "chemical_mass": 46561.0, "monoisotopic_mass": 46561.0 }, "refseq": {}, "gene_names": [ { "name": "RTN4IP1", "type": "recommended", "evidence": [ { "id": "A0A8V0YKC1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKC1" } ] } ], "protein_names": [ { "name": "NAD(P)H oxidoreductase RTN4IP1, mitochondrial", "type": "recommended", "evidence": [ { "id": "A0A8V0YKC1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKC1/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKC1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKC1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RTN4IP1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKC1", "locus": { "chromosome": "3", "start_pos": 67826550, "end_pos": 67804349, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013076", "url": "https://www.ensembl.org/id/ENSGALG00010013076" } ] } } ], "crossref": [ { "id": "A0A8V0YKC1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YKC1", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd08248", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd08248", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "421782", "url": "https://www.ncbi.nlm.nih.gov/gene/421782", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002364", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002364", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011032", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011032", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013149", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013149", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013154", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013154", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020843", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020843", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036291", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036291", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037397", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037397", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050700", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050700", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "TSWQALK", "url": "https://omabrowser.org/oma/group/TSWQALK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YBY5", "url": "https://www.orthodb.org/?gene=A0A8V0YBY5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YKB6", "url": "https://www.orthodb.org/?gene=A0A8V0YKB6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YKC1", "url": "https://www.orthodb.org/?gene=A0A8V0YKC1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YQ62", "url": "https://www.orthodb.org/?gene=A0A8V0YQ62", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11695", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11695", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11695:SF294", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11695:SF294", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00107", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00107", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08240", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08240", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13602", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13602", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "83235", "url": "https://www.rhea-db.org/rhea/83235", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "83239", "url": "https://www.rhea-db.org/rhea/83239", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "83243", "url": "https://www.rhea-db.org/rhea/83243", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "83247", "url": "https://www.rhea-db.org/rhea/83247", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YBY5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBY5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YBY5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBY5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YKB6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKB6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YKB6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKB6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YKC1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKC1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YKC1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKC1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQ62", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ62", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQ62-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ62-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLARRALQWAARRGGQRPPVRGLRGSPRARSAMPSWVIDRYGRNEVLRFTRDMVFPVIQYPNEVIVKVHAASLNPIDLSMRSGYGATALNMKRDPLKIKSMDTEFPLTLGRDASGVIMECGLSVSYFKPGDEVWAAIPPWKQGTLSEFVVASANEVSFKPKCLSHVEAASLPYVGLTAWSAINKVGGLNQSNCSGKRVLILGASGGVGTFAVQLVKAWGAHVTAVCSHDAGTLMRKLGADDVIDYKSGSLEQQLKTLPSFDFILDNVGGSTEKWALDLLKKWSGATYVTLVTPFLINVDRLGVADGMLQTGVTIGSKTVKHLLKGVHYRWAFFMPSGPSLDEIAQLVDSGKQSTCPTERAITGSRSAKQDKCACWYLQQKGLNIFFSDIQPVIEQVFPFSEVPKAFQKLEEGHARGKTVIDVVNKK", "length": 426, "header": "tr|A0A8V0YKC1-1|A0A8V0YKC1_CHICK Isoform 1 of NAD(P)H oxidoreductase RTN4IP1, mitochondrial OS=Gallus gallus OX=9031 GN=RTN4IP1 PE=1 SV=1 CANONICAL=A0A8V0YKC1-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YBY5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKC1/entry#A0A8V0YBY5-1", "sequence": { "sequence": "MLARRALQWAARRGGQRPPVRGLRGSPRARSAMPSWVIDRYGRNEVLRFTRDMVFPVIQYPNEVIVKVHAASLNPIDLSMRSGYGATALNMKRDPLKIKSMDTEFPLTLGRDASGVIMECGLSVSYFKPGDEVSFKPKCLSHVEAASLPYVGLTAWSAINKVGGLNQSNCSGKRVLILGASGGVGTFAVQLVKAWGAHVTAVCSHDAGTLMRKLGADDVIDYKSGSLEQQLKTLPSFDFILDNVGGSTEKWALDLLKKWSGATYVTLVTPFLINVDRLGVADGMLQTGVTIGSKTVKHLLKGVHYRWAFFMPSGPSLDEIAQLVDSGKIQPVIEQVFPFSEVPKAFQKLEEGHARGKTVIDVVNKK", "length": 366, "header": "tr|A0A8V0YBY5-1|A0A8V0YBY5_CHICK Computationally mapped isoform of Reticulon 4 interacting protein 1 OS=Gallus gallus OX=9031 GN=RTN4IP1 PE=1 SV=1 CANONICAL=A0A8V0YKC1-1" }, "locus": { "chromosome": "3", "start_pos": 67824396, "end_pos": 67804427, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031351.1", "url": "https://www.ensembl.org/id/ENSGALT00010031351.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018285.1", "url": "https://www.ensembl.org/id/ENSGALP00010018285.1" } ] } }, { "isoform_ac": "A0A8V0YKB6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKC1/entry#A0A8V0YKB6-1", "sequence": { "sequence": "MLARRALQWAARRGGQRPPVRGLRGSPRARSAMPSWVIDRYGRNEVLRFTRDMVFPVIQYPNEVIVKVHAASLNPIDLSMRSGYGATALNMKRDPLKIKSMDTEFPLTLGRDASGVIMECGLSVSYFKPGDEVWAAIPPWKQGTLSEFVVASANEVSFKPKCLSHVEAASLPYVGLTAWSAINKVGGLNQSNCSGKRVCYFIVLSDENFNVSIGCNNS", "length": 218, "header": "tr|A0A8V0YKB6-1|A0A8V0YKC1_CHICK Computationally mapped isoform of NAD(P)H oxidoreductase RTN4IP1, mitochondrial OS=Gallus gallus OX=9031 GN=RTN4IP1 PE=1 SV=1 CANONICAL=A0A8V0YKC1-1" }, "locus": { "chromosome": "3", "start_pos": 67808188, "end_pos": 67804427, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031349.1", "url": "https://www.ensembl.org/id/ENSGALT00010031349.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018283.1", "url": "https://www.ensembl.org/id/ENSGALP00010018283.1" } ] } }, { "isoform_ac": "A0A8V0YKC1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKC1/entry#A0A8V0YKC1-1", "sequence": { "sequence": "MLARRALQWAARRGGQRPPVRGLRGSPRARSAMPSWVIDRYGRNEVLRFTRDMVFPVIQYPNEVIVKVHAASLNPIDLSMRSGYGATALNMKRDPLKIKSMDTEFPLTLGRDASGVIMECGLSVSYFKPGDEVWAAIPPWKQGTLSEFVVASANEVSFKPKCLSHVEAASLPYVGLTAWSAINKVGGLNQSNCSGKRVLILGASGGVGTFAVQLVKAWGAHVTAVCSHDAGTLMRKLGADDVIDYKSGSLEQQLKTLPSFDFILDNVGGSTEKWALDLLKKWSGATYVTLVTPFLINVDRLGVADGMLQTGVTIGSKTVKHLLKGVHYRWAFFMPSGPSLDEIAQLVDSGKQSTCPTERAITGSRSAKQDKCACWYLQQKGLNIFFSDIQPVIEQVFPFSEVPKAFQKLEEGHARGKTVIDVVNKK", "length": 426, "header": "tr|A0A8V0YKC1-1|A0A8V0YKC1_CHICK Isoform 1 of NAD(P)H oxidoreductase RTN4IP1, mitochondrial OS=Gallus gallus OX=9031 GN=RTN4IP1 PE=1 SV=1 CANONICAL=A0A8V0YKC1-1" }, "locus": { "chromosome": "3", "start_pos": 67824396, "end_pos": 67804427, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031355.1", "url": "https://www.ensembl.org/id/ENSGALT00010031355.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018288.1", "url": "https://www.ensembl.org/id/ENSGALP00010018288.1" } ] } }, { "isoform_ac": "A0A8V0YQ62-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKC1/entry#A0A8V0YQ62-1", "sequence": { "sequence": "MLARRALQWAARRGGQRPPVRGLRGSPRARSAMPSWVIDRYGRNEVLRFTRDMVFPVIQYPNEVIVKVHAASLNPIDLSMRSGYGATALNMKRDPLKIKSMDTEFPLTLGRDASGVIMECGLSVSYFKPGDEVWAAIPPWKQGTLSEFVVASANEVSFKPKCLSHVEAASLPYVGLTAWSAINKVGGLNQSNCSGKRVLILGASGGVGTFAVQLVKAWGAHVTAVCSHDAGTLMRKLGADDVIDYKSGSLEQQLKTLPSFDFILDNVGGSTEKWALDLLKKWSGATYVTLVTPFLINVDRLGVADGMLQTGVTIGSKTVKHLLKGVHYRWAFFMPSGPSLDEIAQLVDSGKIQPVIEQVFPFSEVPKAFQKLEEGHARGKTVIDVVNKK", "length": 389, "header": "tr|A0A8V0YQ62-1|A0A8V0YQ62_CHICK Computationally mapped isoform of NAD(P)H oxidoreductase RTN4IP1, mitochondrial OS=Gallus gallus OX=9031 GN=RTN4IP1 PE=1 SV=1 CANONICAL=A0A8V0YKC1-1" }, "locus": { "chromosome": "3", "start_pos": 67824396, "end_pos": 67804427, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031352.1", "url": "https://www.ensembl.org/id/ENSGALT00010031352.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018286.1", "url": "https://www.ensembl.org/id/ENSGALP00010018286.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A5K1VV69-1", "protein_name": "NAD(P)H oxidoreductase RTN4IP1, mitochondrial", "gene_name": "RTN4IP1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGFLKICVLRRNACTALCFWRNQIVEKPLVRKITTTSPRSTVMPAWVIDKYGNNEVLRFTQNMMLPMIHYPNEVVIKVHAASINPIDVNMRSGYGATALNMKRDPLHIRIKGEEFPLTLGRDVSGVVMECGLDVKYFKPGDEVWAAVPPWKQGTLSEFVVVSGNEVSHKPKSLTHTQAASLPYVALTAWSAINKVGGLNDKNCRGKRVLILGASGGVGTFAIQVMKAWDAHVTAVCSQDASELVRKLGADDVIDYKSGNMEEQLKSFKPFDFILDNVGGSTETWALNFLKKWSGATYVTLVTPFLLNMDRLGIADGMLQTGVTVGSKTLKHFWQGVHYRWAFFMASGPYLDDIAELVDAGKIQPVIEKTFPFSKVPEAFLKVERGHARGKTVIKVV", "length": 396 }, "evidence": [ { "id": "A0A8V0YKC1", "url": "https://omabrowser.org/oma/group/A0A8V0YKC1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3GXJ0-1", "protein_name": "NAD(P)H oxidoreductase RTN4IP1, mitochondrial", "gene_name": "Rtn4ip1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MEVLKSCVLTRSVCAAAACFWRSKAIPKRPIREISTTPARSTVMPAWVIDKYGKNEVLRFNQNMMLPIIHYPNEVIIKVHAASVNPIDVNMRSGYGATALNMKRDPLHMRTKGEEFPLTLGRDVSGVVMECGLDVKYFQPGDEVWAAVPPWKQGTLSEFVVVSGNEVSYKPKSLTHTQAASLPYVALTAWSAINKVGGLNAKNCMGKRALILGASGGVGTFAIQIMKAWGAHVTAVCSQDASKLVRKLGADEVVDYTSGSVEEQLKSLKLFDFILDNVGGSTETWALNFLKKWSGATYVTLVTPFLLNMDQLGIADGMLQTGVTMGTKTLKHFWQGVHYRWAFFMASGPYLDEICELVDEGKIRPVIEQTFPFSEVPEAFLKVERGHARGKTVVKVI", "length": 397 }, "evidence": [ { "id": "A0A8V0YKC1", "url": "https://omabrowser.org/oma/group/A0A8V0YKC1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q0VC50-1", "protein_name": "NAD(P)H oxidoreductase RTN4IP1, mitochondrial", "gene_name": "RTN4IP1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGFLKTCVFRRNACTAVCFWRSQVVQKPSVRKISTTSPRSTVMPAWVIDKYGSNEVLRFTQNMMIPMIHYPNEVIIKVHAASINPIDVNMRSGYGATALNMKRDPLHVKIKGEEFPLTLGRDVSGVVMECGLDVRYFKPGDEVWAAVPPWKQGTLSEFVVVSGNEVSHKPRSLTHTQAASLPYVALTAWSAINKVGGLNDRNCTGKRVLILGASGGVGTFAIQVMKAWDAHVTAVCSQDASELVRKLGADDVIDYKSGNVEAQLKSSKPFDFILDNVGGSTETWALKFLKKWSGATYVTLVTPFLLNMDRLGIADGMLQTGVTVGSKTLKHFWQGVHYRWAFFMASGPCLDDIAELVEAGKIQPVIEKTFPFSKVPEAFLKVERGHARGKTVINVV", "length": 396 }, "evidence": [ { "id": "A0A8V0YKC1", "url": "https://omabrowser.org/oma/group/A0A8V0YKC1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q8WWV3-1", "protein_name": "NAD(P)H oxidoreductase RTN4IP1, mitochondrial", "gene_name": "RTN4IP1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEFLKTCVLRRNACTAVCFWRSKVVQKPSVRRISTTSPRSTVMPAWVIDKYGKNEVLRFTQNMMMPIIHYPNEVIVKVHAASVNPIDVNMRSGYGATALNMKRDPLHVKIKGEEFPLTLGRDVSGVVMECGLDVKYFKPGDEVWAAVPPWKQGTLSEFVVVSGNEVSHKPKSLTHTQAASLPYVALTAWSAINKVGGLNDKNCTGKRVLILGASGGVGTFAIQVMKAWDAHVTAVCSQDASELVRKLGADDVIDYKSGSVEEQLKSLKPFDFILDNVGGSTETWAPDFLKKWSGATYVTLVTPFLLNMDRLGIADGMLQTGVTVGSKALKHFWKGVHYRWAFFMASGPCLDDIAELVDAGKIRPVIEQTFPFSKVPEAFLKVERGHARGKTVINVV", "length": 396 }, "evidence": [ { "id": "A0A8V0YKC1", "url": "https://omabrowser.org/oma/group/A0A8V0YKC1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q924D0-1", "protein_name": "NAD(P)H oxidoreductase RTN4IP1, mitochondrial", "gene_name": "Rtn4ip1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGVLKTCVLRRSACAAACFWRRTVIPKPPFRGISTTSARSTVMPAWVIDKYGKNEVLRFTQNMMLPIIHYPNEVIIKVHAASVNPIDVNMRSGYGATALNMKRDPLHMKTKGEEFPLTLGRDVSGVVMECGLDVKYFQPGDEVWAAVPPWKQGTLSEFVVVSGNEVSHKPKSLTHTQAASLPYVALTAWSAINKVGGLSDKNCKGKRALILGASGGVGTFAIQVMKAWGAHVTAVCSKDASELVRKLGADEVIDYTLGSVEEQLKSLKLFDFILDNVGGSTETWALNFLKKWSGATYVTLVTPFLLNMDRLGVADGMLQTGVTVGTKALKHLWQGVHYRWAFFMASGPYLDEIAELVDAGKIRPVIERTFPFSEVPEAFLKVERGHARGKTVVNVV", "length": 396 }, "evidence": [ { "id": "A0A8V0YKC1", "url": "https://omabrowser.org/oma/group/A0A8V0YKC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9ZUC1-1", "protein_name": "NADPH-dependent alkenal/one oxidoreductase, chloroplastic", "gene_name": "AOR", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MNAALATTTATTPVLRRETPLLHYCSLTTKSPVYQINRVRFGSCVQTVSKKFLKISASSQSASAAVNVTADASIPKEMKAWVYSDYGGVDVLKLESNIVVPEIKEDQVLIKVVAAALNPVDAKRRQGKFKATDSPLPTVPGYDVAGVVVKVGSAVKDLKEGDEVYANVSEKALEGPKQFGSLAEYTAVEEKLLALKPKNIDFAQAAGLPLAIETADEGLVRTEFSAGKSILVLNGAGGVGSLVIQLAKHVYGASKVAATASTEKLELVRSLGADLAIDYTKENIEDLPDKYDVVFDAIGMCDKAVKVIKEGGKVVALTGAVTPPGFRFVVTSNGDVLKKLNPYIESGKVKPVVDPKGPFPFSRVADAFSYLETNHATGKVVVYPIP", "length": 386 }, "evidence": [ { "id": "A0A8V0YKC1", "url": "https://omabrowser.org/oma/group/A0A8V0YKC1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 6, "go_terms": [ { "name": "alcohol dehydrogenase [NAD(P)+] activity", "id": "GO:0018455", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0018455", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKC1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKC1" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", 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], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "nervous system development", "id": "GO:0007399", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007399", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKC1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKC1" } ], "pmid": "" }, { "name": "ubiquinone biosynthetic process", "id": "GO:0006744", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006744", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKC1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKC1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 189, "end_pos": 191, "annotation": "n_glycosylation_sequon" }, { "start_pos": 192, "end_pos": 194, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "83235", "name": "", "equation": "a 3-demethylubiquinone + NADH + 2 H(+) = a 3-demethylubiquinol + NAD(+)", "summary": "", 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predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052551.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015151956.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015151956", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015151956" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKB9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKB9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LOC771545", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKB9", "locus": {} } ], "crossref": [ { "id": "A0A8V0YKB9", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YKB9", "database": "AlphaFoldDB", "categories": [] }, { "id": "771545", "url": "https://www.ncbi.nlm.nih.gov/gene/771545", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003598", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003598", "database": 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"categories": [ "Enzyme and Pathway" ] }, { "id": "XP_015151956", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015151956", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YKB9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKB9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YKB9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKB9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YKZ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKZ8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YKZ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKZ8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": 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"evidence": [ { "id": "A0A8V0YKD9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKD9/entry#names_and_taxonomy" } ] }, { "name": "DNA-binding protein RFX8 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_416912", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_416912" } ] }, { "name": "Regulatory factor X 8", "type": "synonym", "evidence": [ { "id": "A0A8V0YKD9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKD9/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_416912.4. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_416912", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_416912" } ] }, { "annotation": "May be a transcription factor.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKD9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKD9#function" }, { "database": "UniProtKB", "id": "ARBA00054388", "url": "https://www.uniprot.org/uniprotkb/ARBA00054388#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKD9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKD9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RFX8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKD9", "locus": { "chromosome": "1", "start_pos": 133612229, "end_pos": 133644653, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013525", "url": "https://www.ensembl.org/id/ENSGALG00010013525" } ] } } ], "crossref": [ { "id": "A0A8V0YKD9", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YKD9", "database": "AlphaFoldDB", "categories": [] }, { "id": "418713", "url": "https://www.ncbi.nlm.nih.gov/gene/418713", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003150", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003150", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036388", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036388", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036390", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036390", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039779", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039779", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057321", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057321", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:418713", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418713", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YKD9", "url": "https://www.orthodb.org/?gene=A0A8V0YKD9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12619", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12619", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12619:SF24", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12619:SF24", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02257", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02257", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25340", "url": 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"sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YKE2-1", "uniprot_ac": "A0A8V0YKE2", "uniprot_id": "A0A8V0YKE2_CHICK", "mass": { "chemical_mass": 227293.0, "monoisotopic_mass": 227293.0 }, "refseq": { "ac": "XP_421324", "name": "thyroid receptor-interacting protein 11", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_421324" }, "gene_names": [ { "name": "TRIP11", "type": "recommended", "evidence": [ { "id": "A0A8V0YKE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKE2" } ] }, { "name": "TRIP11", "type": "synonym", "evidence": [ { "id": "XP_421324", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_421324" } ] } ], "protein_names": [ { "name": "Thyroid hormone receptor interactor 11", "type": "synonym", "evidence": [ { "id": "A0A8V0YKE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKE2/entry#names_and_taxonomy" } ] }, { "name": "thyroid receptor-interacting protein 11", "type": "synonym", "evidence": [ { "id": "XP_421324", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_421324" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052536.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_421324.3. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_421324", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_421324" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKE2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKE2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TRIP11", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKE2", "locus": { "chromosome": "5", "start_pos": 44047249, "end_pos": 44077050, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010015234", "url": "https://www.ensembl.org/id/ENSGALG00010015234" } ] } } ], "crossref": [ { "id": "423414", "url": "https://www.ncbi.nlm.nih.gov/gene/423414", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000237", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000237", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019459", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019459", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:423414", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423414", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "RHIAQIS", "url": "https://omabrowser.org/oma/group/RHIAQIS/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YKE2", "url": "https://www.orthodb.org/?gene=A0A8V0YKE2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YRZ0", "url": "https://www.orthodb.org/?gene=A0A8V0YRZ0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YYI9", "url": "https://www.orthodb.org/?gene=A0A8V0YYI9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR18921", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR18921", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR18921:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR18921:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10375", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10375", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-5620924", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5620924", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_421324", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_421324", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YKE2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKE2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YKE2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKE2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YRZ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRZ0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YRZ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRZ0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YYI9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYI9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YYI9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYI9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASWLGGLGSGLGQSLGQVGGSLSSLTGQISSFTKDILLEGAEEVGDAATELHVSNSRLREIESINAAQKSENERLKKVCSDLEEKHEAAELQIKQLSVEYRNQLQQKEVEISHLKARQNALQEQLQKLQTAAQSAQLGGGVSQPATTSASFVPVLRHSSGFEGDDMDFGDIIWSQQEINRLSNEVSRLESEVDHWKQIAQSSKVQGANDAEQSEICKLQNIIKELKQNLSREIDEHQHELSVLQDAHRQKLVEISRRHREELSEYEERIEELEHQLQQDGVSADAMVDSKISEEKKITQNLEGRKAEDLQIIKDLEDEIRKLNQKLSSAKEENKILLKEQELLKVEKIQLTQEYESLKSDFSMLQSSVTEQMKEQKSQSKTPLPEDVVSLQQALLEAEREIARLSSLNQADNPAYMAEDVQAFILDLQLLKEENLKLRNEKEELEKELLNAQHKDENVISAYTEDQNSELRLLKQDLERKEHELNESIAERETLIAELEELDKQNQEATQHMITLKEKLSKQHIETDSITKQLKFDIDVERKKVAKLEMEKMETIKELDTQKEKLSQCSYALNDLHISKQQLQDNVRNLQEQLKKAQDCNLHNKKEIRELQQRLKEREEELSLSLSKSTENIKQESSHSSQDLILKESDVEIVELQKKQLENKQLNEDLEKSLSDLKTENGKLMAAFEELKQELNDTISEKNKICLEKDTVVEALKLEKRHLETELNQTEKRLFEQAQKYEQTIEELSNARSMNTTALQLEHERLVKLNQEKDFKIAELKRSMEQMEVDHQETKEMLTTSLGGQKQLTELLKEKEEFIEKLKNQASLVKQELEEYMEVSKKQDVLKQNVEEKDKSLAIMKEENNHLKEEIERLKDQQSRATPVVEPKTLDIIIELESEVTQLKVIKNSLEEEIEVHKKTIEDQNQKTVQLQQSLQEQRKEIDESKFQCEQMNVAHERLSLEKDEEIKKLQKTIEQIKTQLHKERQVIQTDSTDLFQETKVQTLNGENGNEKHDLSKAEIERLVKGIKEREMEIKLLNEKNVSLSQQIDQLSKDEVGKLTRIIQEKDLEIQALSARVSSASYRQDVLGLQQQLQAYVMEREQVLAVLSEKTRENSQLKTEYHKIMDMVAAKEAALVRLQEENQKLSNRFENSGQDMFRETIQNLSRIIREKDIEIDALSQKCQTLLTVLQTSSTGTDNGSGGVNSNQFEELLQERDKLKQQVKKMEEWKQQVITTVQNMQHESAHLQEELQKLQAQISVESDSNSKLQVDYNGLIQSYEQNEKKLRSFSQELAQVQHTIGQLHNTRDLLLGKLDLVTPSATMASIISQPSVMQSSAPEVLSDESKLLQKELEQLKKKLQEKDSTIRTLQENNQRLSDSVATASEFERRSQEETDSEMRQIREKHDVLQKSLREKDILIKSKSDQLLSVSENLSNKENENELLKQAVTNLKERNLILEMDIRKLKEENEKIVVRCREKETEFRALQETNMQFSMMLKEKEFESHSMKEKALAFEKLLKEKEQGKTGELNQLLNEVKSMQEKAVTFQQERDQVMVALKQKQMESSALQSEIQHLHEKEQRLNQELERLRNHLIEMEDSYTREALAAEDRETKLRKKVSILEEKLVSSSTAVENASHQANLQVESLQEQLNLVSKQRDETVLQLAISQDQVKQYALSLTNLQMVLEQFQQEEKAMYSAELEKHQKETAEWKKKAKNLEEKVISLQENLEEANAALDAASRLTEQLDVKEEQIEELKKEGEIRREMLEDVQNKLMNLINSTEGKVDKLLMRNLFIGHFHTPKNKRNEVLRLMGSILGMKKEELDQLLSEDQRGVTRWVTGWLGGGTGSKSVPSTPLRPTHQTGFNSSFSELFVKFLETESCPSLPPPKLSVHDMKPLGAAGTGKTSSTPSSGQISDSGVSGISRRPDTNPFIAPRSAAVPLITPAPSSGHLLMKPISDALPTFTPLPVSPDASAGAVLKDLLKQ", "length": 1980, "header": "tr|A0A8V0YKE2-1|A0A8V0YKE2_CHICK Isoform 1 of Thyroid hormone receptor interactor 11 OS=Gallus gallus OX=9031 GN=TRIP11 PE=1 SV=1 CANONICAL=A0A8V0YKE2-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YKE2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKE2/entry#A0A8V0YKE2-1", "sequence": { "sequence": "MASWLGGLGSGLGQSLGQVGGSLSSLTGQISSFTKDILLEGAEEVGDAATELHVSNSRLREIESINAAQKSENERLKKVCSDLEEKHEAAELQIKQLSVEYRNQLQQKEVEISHLKARQNALQEQLQKLQTAAQSAQLGGGVSQPATTSASFVPVLRHSSGFEGDDMDFGDIIWSQQEINRLSNEVSRLESEVDHWKQIAQSSKVQGANDAEQSEICKLQNIIKELKQNLSREIDEHQHELSVLQDAHRQKLVEISRRHREELSEYEERIEELEHQLQQDGVSADAMVDSKISEEKKITQNLEGRKAEDLQIIKDLEDEIRKLNQKLSSAKEENKILLKEQELLKVEKIQLTQEYESLKSDFSMLQSSVTEQMKEQKSQSKTPLPEDVVSLQQALLEAEREIARLSSLNQADNPAYMAEDVQAFILDLQLLKEENLKLRNEKEELEKELLNAQHKDENVISAYTEDQNSELRLLKQDLERKEHELNESIAERETLIAELEELDKQNQEATQHMITLKEKLSKQHIETDSITKQLKFDIDVERKKVAKLEMEKMETIKELDTQKEKLSQCSYALNDLHISKQQLQDNVRNLQEQLKKAQDCNLHNKKEIRELQQRLKEREEELSLSLSKSTENIKQESSHSSQDLILKESDVEIVELQKKQLENKQLNEDLEKSLSDLKTENGKLMAAFEELKQELNDTISEKNKICLEKDTVVEALKLEKRHLETELNQTEKRLFEQAQKYEQTIEELSNARSMNTTALQLEHERLVKLNQEKDFKIAELKRSMEQMEVDHQETKEMLTTSLGGQKQLTELLKEKEEFIEKLKNQASLVKQELEEYMEVSKKQDVLKQNVEEKDKSLAIMKEENNHLKEEIERLKDQQSRATPVVEPKTLDIIIELESEVTQLKVIKNSLEEEIEVHKKTIEDQNQKTVQLQQSLQEQRKEIDESKFQCEQMNVAHERLSLEKDEEIKKLQKTIEQIKTQLHKERQVIQTDSTDLFQETKVQTLNGENGNEKHDLSKAEIERLVKGIKEREMEIKLLNEKNVSLSQQIDQLSKDEVGKLTRIIQEKDLEIQALSARVSSASYRQDVLGLQQQLQAYVMEREQVLAVLSEKTRENSQLKTEYHKIMDMVAAKEAALVRLQEENQKLSNRFENSGQDMFRETIQNLSRIIREKDIEIDALSQKCQTLLTVLQTSSTGTDNGSGGVNSNQFEELLQERDKLKQQVKKMEEWKQQVITTVQNMQHESAHLQEELQKLQAQISVESDSNSKLQVDYNGLIQSYEQNEKKLRSFSQELAQVQHTIGQLHNTRDLLLGKLDLVTPSATMASIISQPSVMQSSAPEVLSDESKLLQKELEQLKKKLQEKDSTIRTLQENNQRLSDSVATASEFERRSQEETDSEMRQIREKHDVLQKSLREKDILIKSKSDQLLSVSENLSNKENENELLKQAVTNLKERNLILEMDIRKLKEENEKIVVRCREKETEFRALQETNMQFSMMLKEKEFESHSMKEKALAFEKLLKEKEQGKTGELNQLLNEVKSMQEKAVTFQQERDQVMVALKQKQMESSALQSEIQHLHEKEQRLNQELERLRNHLIEMEDSYTREALAAEDRETKLRKKVSILEEKLVSSSTAVENASHQANLQVESLQEQLNLVSKQRDETVLQLAISQDQVKQYALSLTNLQMVLEQFQQEEKAMYSAELEKHQKETAEWKKKAKNLEEKVISLQENLEEANAALDAASRLTEQLDVKEEQIEELKKEGEIRREMLEDVQNKLMNLINSTEGKVDKLLMRNLFIGHFHTPKNKRNEVLRLMGSILGMKKEELDQLLSEDQRGVTRWVTGWLGGGTGSKSVPSTPLRPTHQTGFNSSFSELFVKFLETESCPSLPPPKLSVHDMKPLGAAGTGKTSSTPSSGQISDSGVSGISRRPDTNPFIAPRSAAVPLITPAPSSGHLLMKPISDALPTFTPLPVSPDASAGAVLKDLLKQ", "length": 1980, "header": "tr|A0A8V0YKE2-1|A0A8V0YKE2_CHICK Isoform 1 of Thyroid hormone receptor interactor 11 OS=Gallus gallus OX=9031 GN=TRIP11 PE=1 SV=1 CANONICAL=A0A8V0YKE2-1" }, "locus": { "chromosome": "5", "start_pos": 44076851, "end_pos": 44049160, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010036710.1", "url": "https://www.ensembl.org/id/ENSGALT00010036710.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021407.1", "url": "https://www.ensembl.org/id/ENSGALP00010021407.1" } ] } }, { "isoform_ac": "A0A8V0YRZ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKE2/entry#A0A8V0YRZ0-1", "sequence": { "sequence": "MASWLGGLGSGLGQSLGQVGGSLSSLTGQISSFTKDILLEGAEEVGDAATELHVSNSRLREIESINAAQKSENERLKKVCSDLEEKHEAAELQIKQLSVEYRNQLQQKEVEISHLKARQNALQEQLQKLQTAAQSAQLGGGVSQPATTSASFVPVLRHSSGFEGDDMDFGDIIWSQQEINRLSNEVSRLESEVDHWKQIAQSSKVQGANDAEQSEICKLQNIIKELKQNLSREIDEHQHELSVLQDAHRQKLVEISRRHREELSEYEERIEELEHQLQQDGVSADAMVDSKISEEKKITQNLEGRKAEDLQIIKDLEDEIRKLNQKLSSAKEENKILLKEQELLKVEKIQLTQEYESLKSDFSMLQSSVTEQMKEQKSQSKTPLPEDVVSLQQALLEAEREIARLSSLNQADNPAYMAEDVQAFILDLQLLKEENLKLRNEKEELEKELLNAQHKDENVISAYTEDQNSELRLLKQDLERKEHELNESIAERETLIAELEELDKQNQEATQHMITLKEKLSKQHIETDSITKQLKFDIDVERKKVAKLEMEKMETIKELDTQKEKLSQCSYALNDLHISKQQLQDNVRNLQEQLKKAQDCNLHNKKEIRELQQRLKEREEELSLSLSKSTENIKQESSHSSQDLILKESDVEIVELQKKQLENKQLNEDLEKSLSDLKTENGKLMAAFEELKQELNDTISEKNKICLEKDTVVEALKLEKRHLETELNQTEKRLFEQAQKYEQTIEELSNARSMNTTALQLEHERLVKLNQEKDFKIAELKRSMEQMEVDHQETKEMLTTSLGGQKQLTELLKEKEEFIEKLKNQASLVKQELEEYMEVSKKQDVLKQNVEEKDKSLAIMKEENNHLKEEIERLKDQQSRATPVVEPKTLDIIIELESEVTQLKVIKNSLEEEIEVHKKTIEDQNQKTVQLQQSLQEQRKEIDESKFQCEQMNVAHERLSLEKDEEIKKLQKTIEQIKTQLHKERQVIQTDSTDLFQETKVQTLNGENGNEKHDLSKAEIERLVKGIKEREMEIKLLNEKNVSLSQQIDQLSKDEVGKLTRIIQEKDLEIQALSARVSSASYRQDVLGLQQQLQAYVMEREQVLAVLSEKTRENSQLKTEYHKIMDMVAAKEAALVRLQEENQKLSNRFENSGQDMFRETIQNLSRIIREKDIEIDALSQKCQTLLTVLQTSSTGTDNGSGGVNSNQFEELLQERDKLKQQVITTVQNMQHESAHLQEELQKLQAQISVESDSNSKLQVDYNGLIQSYEQNEKKLRSFSQELAQVQHTIGQLHNTRDLLLGKLDLVTPSATMASIISQPSVMQSSAPEVLSDESKLLQKELEQLKKKLQEKDSTIRTLQENNQRLSDSVATASEFERRSQEETDSEMRQIREKHDVLQKSLREKDILIKSKSDQLLSVSENLSNKENENELLKQAVTNLKERNLILEMDIRKLKEENEKIVVRCREKETEFRALQETNMQFSMMLKEKEFESHSMKEKALAFEKLLKEKEQGKTGELNQLLNEVKSMQEKAVTFQQERDQVMVALKQKQMESSALQSEIQHLHEKEQRLNQELERLRNHLIEMEDSYTREALAAEDRETKLRKKVSILEEKLVSSSTAVENASHQANLQVESLQEQLNLVSKQRDETVLQLAISQDQVKQYALSLTNLQMVLEQFQQEEKAMYSAELEKHQKETAEWKKKAKNLEEKVISLQENLEEANAALDAASRLTEQLDVKEEQIEELKKEGEIRREMLEDVQNKLMNLINSTEGKVDKLLMRNLFIGHFHTPKNKRNEVLRLMGSILGMKKEELDQLLSEDQRGVTRWVTGWLGGGTGSKSVPSTPLRPTHQTGFNSSFSELFVKFLETESCPSLPPPKLSVHDMKPLGAAGTGKTSSTPSSGQISDSGVSGISRRPDTNPFIAPRSAAVPLITPAPSSGHLLMKPISDALPTFTPLPVSPDASAGAVLKDLLKQ", "length": 1970, "header": "tr|A0A8V0YRZ0-1|A0A8V0YRZ0_CHICK Computationally mapped isoform of Thyroid hormone receptor interactor 11 OS=Gallus gallus OX=9031 GN=TRIP11 PE=1 SV=1 CANONICAL=A0A8V0YKE2-1" }, "locus": { "chromosome": "5", "start_pos": 44076851, "end_pos": 44049160, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010036707.1", "url": "https://www.ensembl.org/id/ENSGALT00010036707.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021406.1", "url": "https://www.ensembl.org/id/ENSGALP00010021406.1" } ] } }, { "isoform_ac": "A0A8V0YYI9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKE2/entry#A0A8V0YYI9-1", "sequence": { "sequence": "MYKQMLKQCKEKILDAATELHVSNSRLREIESINAAQKSENERLKKVCSDLEEKHEAAELQIKQLSVEYRNQLQQKEVEISHLKARQNALQEQLQKLQTAAQSAQLGGGVSQPATTSASFVPVLRHSSGFEGDDMDFGDIIWSQQEINRLSNEVSRLESEVDHWKQIAQSSKVQGANDAEQSEICKLQNIIKELKQNLSREIDEHQHELSVLQDAHRQKLVEISRRHREELSEYEERIEELEHQLQQDGVSADAMVDSKISEEKKITQNLEGRKAEDLQIIKDLEDEIRKLNQKLSSAKEENKILLKEQELLKVEKIQLTQEYESLKSDFSMLQSSVTEQMKEQKSQSKTPLPEDVVSLQQALLEAEREIARLSSLNQADNPAYMAEDVQAFILDLQLLKEENLKLRNEKEELEKELLNAQHKDENVISAYTEDQNSELRLLKQDLERKEHELNESIAERETLIAELEELDKQNQEATQHMITLKEKLSKQHIETDSITKQLKFDIDVERKKVAKLEMEKMETIKELDTQKEKLSQCSYALNDLHISKQQLQDNVRNLQEQLKKAQDCNLHNKKEIRELQQRLKEREEELSLSLSKSTENIKQESSHSSQDLILKESDVEIVELQKKQLENKQLNEDLEKSLSDLKTENGKLMAAFEELKQELNDTISEKNKICLEKDTVVEALKLEKRHLETELNQTEKRLFEQAQKYEQTIEELSNARSMNTTALQLEHERLVKLNQEKDFKIAELKRSMEQMEVDHQETKEMLTTSLGGQKQLTELLKEKEEFIEKLKNQASLVKQELEEYMEVSKKQDVLKQNVEEKDKSLAIMKEENNHLKEEIERLKDQQSRATPVVEPKTLDIIIELESEVTQLKVIKNSLEEEIEVHKKTIEDQNQKTVQLQQSLQEQRKEIDESKFQCEQMNVAHERLSLEKDEEIKKLQKTIEQIKTQLHKERQVIQTDSTDLFQETKVQTLNGENGNEKHDLSKAEIERLVKGIKEREMEIKLLNEKNVSLSQQIDQLSKDEVGKLTRIIQEKDLEIQALSARVSSASYRQDVLGLQQQLQAYVMEREQVLAVLSEKTRENSQLKTEYHKIMDMVAAKEAALVRLQEENQKLSNRFENSGQDMFRETIQNLSRIIREKDIEIDALSQKCQTLLTVLQTSSTGTDNGSGGVNSNQFEELLQERDKLKQQVKKMEEWKQQVITTVQNMQHESAHLQEELQKLQAQISVESDSNSKLQVDYNGLIQSYEQNEKKLRSFSQELAQVQHTIGQLHNTRDLLLGKLDLVTPSATMASIISQPSVMQSSAPEVLSDESKLLQKELEQLKKKLQEKDSTIRTLQENNQRLSDSVATASEFERRSQEETDSEMRQIREKHDVLQKSLREKDILIKSKSDQLLSVSENLSNKENENELLKQAVTNLKERNLILEMDIRKLKEENEKIVVRCREKETEFRALQETNMQFSMMLKEKEFESHSMKEKALAFEKLLKEKEQGKTGELNQLLNEVKSMQEKAVTFQQERDQVMVALKQKQMESSALQSEIQHLHEKEQRLNQELERLRNHLIEMEDSYTREALAAEDRETKLRKKVSILEEKLVSSSTAVENASHQANLQVESLQEQLNLVSKQRDETVLQLAISQDQVKQYALSLTNLQMVLEQFQQEEKAMYSAELEKHQKETAEWKKKAKNLEEKVISLQENLEEANAALDAASRLTEQLDVKEEQIEELKKEGEIRREMLEDVQNKLMNLINSTEGKVDKLLMRNLFIGHFHTPKNKRNEVLRLMGSILGMKKEELDQLLSEDQRGVTRWVTGWLGGGTGSKSVPSTPLRPTHQTGFNSSFSELFVKFLETESCPSLPPPKLSVHDMKPLGAAGTGKTSSTPSSGQISDSGVSGISRRPDTNPFIAPRSAAVPLITPAPSSGHLLMKPISDALPTFTPLPVSPDASAGAVLKDLLKQ", "length": 1948, "header": "tr|A0A8V0YYI9-1|A0A8V0YYI9_CHICK Computationally mapped isoform of Thyroid hormone receptor interactor 11 OS=Gallus gallus OX=9031 GN=TRIP11 PE=1 SV=1 CANONICAL=A0A8V0YKE2-1" }, "locus": { "chromosome": "5", "start_pos": 44074661, "end_pos": 44049160, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010036703.1", "url": "https://www.ensembl.org/id/ENSGALT00010036703.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021403.1", "url": "https://www.ensembl.org/id/ENSGALP00010021403.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:423414", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423414", "resource": "KEGG Pathway" }, { "id": "R-GGA-5620924", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5620924", "resource": "Reactome", "description": "Intraflagellar transport" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I5ZKA2-1", "protein_name": "Thyroid hormone receptor interactor 11", "gene_name": "Trip11", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSSWLGGLGSGLGQSLGQVGGSLASLTGQISNFTKDMLMEGTEDVPADLPNSGREENGATHSVLRSENERLKKLYTDLEEKHEASELQIKQQSSSYRSQLQQKEEEINHLKARQTALQDELLRLQVAAQSAHSGAATAPAATAPASFSYGISHPVSAFHEDDMDFGDVISSQQEINRLSNEVSRLESELGHWRHIAQVQGAQSSDQTEICKLQNIIKELKQNRSQEIDDHQHEMSVLQNAHQQKLTEISRRHREELRDYEERIEELENLLQQGGSGVTVTDHSKVYEMQNTIQSLQMERVESSRKIEDLENKIKEIHKRLSSAEHDREVCKKEQERLEMEKRQMAEQCERLKLDCREAQQSALRLTDAVTEDERSLSQSASVAEVLRLQLLSCKLNILYFKEELQTSLSRLSHEYEVIKSTATRDSDLSSQVHDLKHNLEAKEQELNQSIHENEILMAELEELDKQNQEATKHVILIKEQLSKQQSEGDSVIKRLKEELDDEKKRTHQLEDDKMNIIKELNVQKEKLTHSEQVLSDLQLTKQKLEGKVEDLVDQLSKSEKNNFDIQKENRELREHIRQNEEELSTVRSELTQSQTQGSNSNLKDDLLREKETEVQSLKQNLSEIEQLNEHLKQVAFDLRIENEKLVVACEDVRNQLEESVAGNNQISLEKAAILEWEKAQLEAEPCRAEKRLLEEGRKYRQTVQGPSSTHSPDASALQLEQERLIQLNQEKDFEIAELKKSIEQMDTDHKQTKETLSSSLEEQKQLAQLINEKEICIVKLKEKSSELQRELDRCSQALRKNETLRQTIEEKDRSLGSMKEENNHLQEELERLREQQSRAVPVPEPRTLDSTTELESELSQLHTIKDHLEEEIKHHQKMIEDQNQNKMQLLQSLQEQKKAMDEFKYQHEQMSITHSRLFLEKDEEIKNLQKTIEQIKAQLQEERQDSQTENSDIFQETKVQSLNIEIGSEKHDLSKAETERLVKGIKERELEIKLLNEKNISLTKQIDQLSKDEVGKLTQIIQQKDVEIQALHARISSASYSQDVVYLQQQVQAYAMEREKVMVVLSEKTRENSKLKSEYHKMIDILSAKEAALIKLQDENKKMSTRFESSGQDMFKETIQNLSRIIREKDIEIDALSQKCQTLLTVLQTSGTGSEVGGVNSNQFEELLQERDKLKQQVKKMEEWKQQVMTTVQNMQHESAQLQEELHQLQAQVSVDSDNNTKLQVNYTGLIQSYEQNETKLKNFGQELAQVQHSIGQLCTTKDLLLGKLDSMSPQLSPGSSLTTQAAEPLKASQCSGPHESSHLLQQEVDDLRKSLQEKDATIRTLQENNHRLSDSMAASSEGERKEHEQTDSEVKQLKEKQEVLQNLLKEKDLLIKAKSDQLHSSNENFANKVSENELLRQAVTNLKERILILEMDISKLKGENEKVIEASKGKETEYQALQETNMKFSMMLREKEFECHSMREKALAFEQLLKEKEQGKAGELNQLLNAVKSMQEKTVTFQQERDQVMLALKQKQMETSTLQNEVQRLRDKEARLNQELQRLRDHLLESEDSHTREALAAEDREAKLRKKVSVLEEKLVSSSNAMENASHQASVQVESLQEQLNMVSKQRDETALQLSVSQEQVKQYAMSLTNLQMVLEHFQQEEKAMYSAELEKQNQLLTEWKKKAESLEGKVLSLQERLDEANAALDSASRLTEQLDLKEEQIEELKKQNELHQEMLDDAQKKLMSLVNSTEGKVDKVLMRNLFIGHFHTPKNQRHEVLRLMGSILGVKREEMEQLFAEDQGGVTRWMAGWLGGGSKSVPNTPLRPNQQSVFNSVRPTEGHPQLLGVHEGKSLSYLLDTAESRAGRRTDMNPFLAPRSAAVPLINPAGHGPGGPGHLLLKPISDVLPTFTPLPVSPDNSAGVVLKDLLKQ", "length": 1914 }, "evidence": [ { "id": "A0A8V0YKE2", "url": "https://omabrowser.org/oma/group/A0A8V0YKE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8M1P007-1", "protein_name": "Thyroid receptor-interacting protein 11", "gene_name": "trip11", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSSWLGGLGSGLGQSLGQVGGSLSSFTGQISNFTKDILLESAEEVGDAASELQVSNSRLHELESSYTAQRSEYDRLRRINSELEEKLEAAEIQVKQQSVEYRTLLQQKEVEISHLKARQSGLQEEVQKLQQRTQTAINSSSHDAAVLPVTTAATTTTSSSFLHQSSAVHQGFHSDEVDLSDVLWSQQEINRLSNEVHRLEADVSHWRRVAQVSKLPGADGNGDQGEVLKMQRIIKELRDKMAREVDEHQHELAALQDAQRQKMSDISKRHRQELAEYEERIEELEEQLQSEGGNAVQKSSTMQDSIKLQELESTIRSLQEEAELQRKQHRELLATLEEAEHHKTKLEREKEEATAENAELLQNYSRLQKSVNELQARVQEQEGKSMLKAQHDNEIQVLKKALAGAEKEVARLKSFSESGPMEEVEHADILELNTIIDTLRKEKEEVEKEKLVLLDRIALVEERHRSGEPESVGELSLEVSDLKSQLDQREEALKQAHLDIETLTAELEELDKQNQEATQHVIAVKDQLSLQKTQTEAEKARLQSDLNSLLDQRQSLQLELEAHVEKLSQSAFSLNELHMAKQQLEATVKELREKLCKSQDLGKELRQESSELKRALQQRETELTALHEELSHTGEQRNELEVHRKILEARDKDIHDLKAELAEVKVSYERAVSEDFELKIDNRKLTEERTRTLEKTDSLERHIQECQASLSRMSLEKDTRIEALKLEKSQLESELSQTEKRLSDQAKQYQQTIDELTRARSMDASALQTEHERMVKLNQEKDLTISELRREIEQMISDQKDTSEMLDITVAGQNQLTELLQEKDAFAETLKTQAVETQQELETRILRASQECDSLRKSVEEKDKQLGAMKEENSHLKEEIDRLRDQQSRPQLMSEPRTLDIITELENEVAQLKAARDQLKEEVQALRRLSEEQQTTALQSQRSLQSELEQARSRNEQSALNYERLISAKDEEIARLQSEVEGLSTQGRSQIQSVEILQEDKTQSLNGENGNEKHDLSKVEIEKLVKGIKEKETEINQLNEKNLCLTKQLDQLVVSQNELGKLSQMVRQKDLEIQALHARVSGGHGQDVVFLQQQLQAYAVEREQVLAVLNEKTRENSQLRSDYHRIMDIVAAKEAALLKLQQENQRLSTMSDPSGSQEMFRETIQNLSRIIREKDIEIDALTQKCQTLVSVLQTSGCSDPVSGGSGGVSSNQFEELLQERDTLKQQVKKMEEWKQQVITTVRNMQHESAQLHEELLKLQGQVSADSDSSSKLSVDYARLIQSYEQKEKKLGLLSQELAQVQQTISQLTSTKDVLLGKLGSVKQSPELSAMVPSQALAPSNLRGAAPSAQDDHIHQDMQALQRTLAEKESMIRTLQENNHRLSNSASLSESEQRSHAEELKQAREKQESLQRSLREKDLLIKTKGDQLGQVSETLRNRENDNEVLKQAVTNLKERALILELDVKKLKDENEAIASKAREKETEFRALQETNMQVSLLLREREFQFSAVNEKATAMEKMLKDKEQGKSGELNQLLNEVRSMQEKAVLFQQERDQVMMALKQKQMETSALQSELQHTRDKEQRLKQEVERLRNHLLEIEDSYTREALSAQDREAELRRRVTLLDERLTSSSNAVESASQQASFQVESLQEQLNGAVRQRDEALIQLRASQDQVNQYAVSLSNLQMVLEQFQQEEKAMYSAELEKHKREKMEWRNKAESLEEIAAALRINLDEANAALESASRLTDQLDLKDEQIEDLNKQVEVRQEMLEEAQRKLMNLLNTTEGKVDKVLMKNLYLGYFHTPQNKRGEVLRLMGNVLGLDRDEVGQLLKEEVKSGMTGWVSSWLGGRAVQSVPNTPQRPTQAQSLNSSFSEMFVKFLEVESSPALPAPKLPMYDIKPLSAPPPGRSTANTPASGVSGPGKRSGDSNPFLAPRSAAVPLLNPTGAGSTAGAGGHLLMKPISDALPTFTPVPVSAEASGGAVLKDLLKQ", "length": 1984 }, "evidence": [ { "id": "A0A8V0YKE2", "url": "https://omabrowser.org/oma/group/A0A8V0YKE2/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "E9Q512-1", "protein_name": "Thyroid hormone receptor interactor 11", "gene_name": "Trip11", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSWLGGLGSGLGQSLGQVGGSLASLTGQISNFTKDMLLEGTEDVPADFPNSGREENEATHSVLRSENERLKKLYTDLEEKHEASELQIKQQSSSYRSQLQQKEEEINHLKARQLALQDELLRLQSAAQSAHLGSGSAPAASASSSFSYGVSHRVSAFHEDDMDFGDVISSQQEINRLSNEVSRLESELGHWRHIAQTKVQGAQSSDQTEICKLQNIIKELKQNRSQDLDDHQHELSALQNAHQQKLTEISRRHREELSDYEERIEELENLLQQGGSGVTVTDHSKVYEMQNTIQILQMEKVESTKQIEDLENKIKEIHKRLSSAEHDQEVWKKEQERLEVEKREMTEQCERLKLELSEAQQSALRQSDAAVEEETILPHSSSVAEVLRLQQALTDAENEIMRLRSLNQDISLAEDNQKLQMCVQTLEKEKSLLSQEKEELQISLSKLSSEYEVIKSTATRDLDLFSQVHDLKHNLEAKEQELNQSIHENEILMAELEELDKQNQEATKHVILIKDQLSKQQSEGDSVIKKLKEELAGEKQRTHQLEDDKMNIIKELTVQKEKLTHSEQALSDLQLTKQKLEDKVEDLVDQLSKSEKNNFDIQKENHELREHIRQNEEELSTVRSELTQSQTQGSSRNVKDDLLKERETQVQNLKQNLSEVEQLNEHLEQVAFDLRTENEELLEAYEEVRNQLEESVAGNKQISLEKTAMLEWEKAPLETELCRAEKRVLEEERKYEQTVQELSSACSPDTSALQLEQERLIQLNQEKDFEIAELKKSIEQMDTDHKRTKETLSSSLEEQKQLTQLINEKEICIVKLKEKSSELQKELDKCAQTLRKNETLRQTIEEKDRSLGSMKEENNHLQEELERLREQQSRVVPAPEPRTLDSTTELESELSQLHRIKGHLEEEIKHHQKMIEDQNQSKLQLLQSLQEQKKELDEFKYQHEQMSISHTRLFLEKDEEIKNLQKTIEQIKAQLHEERQDSQTENSDIFQETKVQSLSIEHGSEKHDLSKAETERLVKGIKERELEIKLLNEKNTSLTKQIDQLSKDEVGKLTQIIQQKDLEIQALHARISSASYSQDVVYLQQQLHAYAMEREKVMVILNEKTRENSQLKTEYHKVIDIISAKEAALIKLQDENKKMSTRFESSGQDMFKETIQNLSRIIREKDIEIDALSQKCQTLLTVLQTSGTGSEAGGVNSNQFEELLQERDKLKQQVKKMEEWKQQVMTTVQNMQHESAQLQEELHQLQAQVSVDSDNNSKLQVDYTGLIQSYEQNETKLKNFGQELAQVQHSIGQLCNTKDLLLGKLDIMSPQLSSGSSLTSQAAEPLRASQSSEPHESSQLLQQEVDDLRKSLQEKDATIRTLQENNHRLSDSVAASSEVERKEHEQADSEIKQLKEKQEVLQNLLKEKDLLIKAKSDQLHSSNENLANKVNENELLRQAVTNLKERILILEMDISKLKGENEKIVDASKGKETEYQALQETNMKFSMMLREKEFECHSMREKALAFEQLLKEKEQGKAGELNQLLNAVKSMQEKTVTFQQERDQVMLALKQKQMETSTLQNEVQRLRDKESRLNQELQRLRDHLLESEDSHTREALAAEDREAKLRKKVSVLEEKLVSSSNAMENASHQASVQVESLQEQLNMVSKQRDETALQLSVSQEQVKQYALSLANLQMVLEHFQQEEKAMYSAELEKQNHLLAEWKKKAESLEGKVLSLQERLDEANAALDSASRLTEQLDLKEEQIEELKKQNELHQEMLDDAQKKLMSLVNSTEGKVDKVLMRNLFIGHFHTPKHQRHEVLRLMGSILGVKREEMEQLFAEDQGGVTRWMAGWLGGGSKSVPNTPLRPNQQSVFNSSFSELFVKFLETESHPSVPPPKLSVHGLKPLDSPGRRKADTGIPESFRDTAESRAGRRTDVNPFLAPRSAAVPLINPAGHGPGGPGHLLLKPISDVLPTFTPLPVSPDNSAGVVLKDLLKQ", "length": 1976 }, "evidence": [ { "id": "A0A8V0YKE2", "url": "https://omabrowser.org/oma/group/A0A8V0YKE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q15643-1", "protein_name": "Thyroid receptor-interacting protein 11", "gene_name": "TRIP11", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSSWLGGLGSGLGQSLGQVGGSLASLTGQISNFTKDMLMEGTEEVEAELPDSRTKEIEAIHAILRSENERLKKLCTDLEEKHEASEIQIKQQSTSYRNQLQQKEVEISHLKARQIALQDQLLKLQSAAQSVPSGAGVPATTASSSFAYGISHHPSAFHDDDMDFGDIISSQQEINRLSNEVSRLESEVGHWRHIAQTSKAQGTDNSDQSEICKLQNIIKELKQNRSQEIDDHQHEMSVLQNAHQQKLTEISRRHREELSDYEERIEELENLLQQGGSGVIETDLSKIYEMQKTIQVLQIEKVESTKKMEQLEDKIKDINKKLSSAENDRDILRREQEQLNVEKRQIMEECENLKLECSKLQPSAVKQSDTMTEKERILAQSASVEEVFRLQQALSDAENEIMRLSSLNQDNSLAEDNLKLKMRIEVLEKEKSLLSQEKEELQMSLLKLNNEYEVIKSTATRDISLDSELHDLRLNLEAKEQELNQSISEKETLIAEIEELDRQNQEATKHMILIKDQLSKQQNEGDSIISKLKQDLNDEKKRVHQLEDDKMDITKELDVQKEKLIQSEVALNDLHLTKQKLEDKVENLVDQLNKSQESNVSIQKENLELKEHIRQNEEELSRIRNELMQSLNQDSNSNFKDTLLKEREAEVRNLKQNLSELEQLNENLKKVAFDVKMENEKLVLACEDVRHQLEECLAGNNQLSLEKNTIVETLKMEKGEIEAELCWAKKRLLEEANKYEKTIEELSNARNLNTSALQLEHEHLIKLNQKKDMEIAELKKNIEQMDTDHKETKDVLSSSLEEQKQLTQLINKKEIFIEKLKERSSKLQEELDKYSQALRKNEILRQTIEEKDRSLGSMKEENNHLQEELERLREEQSRTAPVADPKTLDSVTELASEVSQLNTIKEHLEEEIKHHQKIIEDQNQSKMQLLQSLQEQKKEMDEFRYQHEQMNATHTQLFLEKDEEIKSLQKTIEQIKTQLHEERQDIQTDNSDIFQETKVQSLNIENGSEKHDLSKAETERLVKGIKERELEIKLLNEKNISLTKQIDQLSKDEVGKLTQIIQQKDLEIQALHARISSTSHTQDVVYLQQQLQAYAMEREKVFAVLNEKTRENSHLKTEYHKMMDIVAAKEAALIKLQDENKKLSTRFESSGQDMFRETIQNLSRIIREKDIEIDALSQKCQTLLAVLQTSSTGNEAGGVNSNQFEELLQERDKLKQQVKKMEEWKQQVMTTVQNMQHESAQLQEELHQLQAQVLVDSDNNSKLQVDYTGLIQSYEQNETKLKNFGQELAQVQHSIGQLCNTKDLLLGKLDIISPQLSSASLLTPQSAECLRASKSEVLSESSELLQQELEELRKSLQEKDATIRTLQENNHRLSDSIAATSELERKEHEQTDSEIKQLKEKQDVLQKLLKEKDLLIKAKSDQLLSSNENFTNKVNENELLRQAVTNLKERILILEMDIGKLKGENEKIVETYRGKETEYQALQETNMKFSMMLREKEFECHSMKEKALAFEQLLKEKEQGKTGELNQLLNAVKSMQEKTVVFQQERDQVMLALKQKQMENTALQNEVQRLRDKEFRSNQELERLRNHLLESEDSYTREALAAEDREAKLRKKVTVLEEKLVSSSNAMENASHQASVQVESLQEQLNVVSKQRDETALQLSVSQEQVKQYALSLANLQMVLEHFQQEEKAMYSAELEKQKQLIAEWKKNAENLEGKVISLQECLDEANAALDSASRLTEQLDVKEEQIEELKRQNELRQEMLDDVQKKLMSLANSSEGKVDKVLMRNLFIGHFHTPKNQRHEVLRLMGSILGVRREEMEQLFHDDQGGVTRWMTGWLGGGSKSVPNTPLRPNQQSVVNSSFSELFVKFLETESHPSIPPPKLSVHDMKPLDSPGRRKRDTNAPESFKDTAESRSGRRTDVNPFLAPRSAAVPLINPAGLGPGGPGHLLLKPISDVLPTFTPLPALPDNSAGVVLKDLLKQ", 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}, { "isoform_ac": "A0A8V0YS07-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKF8/entry#A0A8V0YS07-1", "sequence": { "sequence": "MMDPCECASQRKPSLSFSIEEILKKPSASTTSNETRNRNKYAETSPALKAESPWAFGREHLEGKRKHEEEEDQLCDFPVDHPLHVERKGKRRIRTTFTAEQLQELEKIFQVTHYPDVHIRNQLAAKINLPEARVQIWFQNQRAKWRKHEKFGNFGGLQHLTEVDFIPAPKPDITAPSLIPRKLAATIPSIGYYSPLQGQLTTTWLPSTLSYIPHHLELLPFPKPCLLFNILPAYSAPRSHKLEQSSICASST", "length": 252, "header": "tr|A0A8V0YS07-1|A0A8V0YS07_CHICK Computationally mapped isoform of Intestine-specific homeobox OS=Gallus gallus OX=9031 GN=ISX PE=4 SV=1 CANONICAL=A0A8V0YKF8-1" }, "locus": { "chromosome": "1", "start_pos": 52308137, "end_pos": 52282858, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010036735.1", "url": "https://www.ensembl.org/id/ENSGALT00010036735.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021421.1", "url": "https://www.ensembl.org/id/ENSGALP00010021421.1" } ] } }, { "isoform_ac": "A0A8V0YTJ5-1", "url": 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"name": "neuron development", "id": "GO:0048666", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048666", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKF8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKF8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "RNA polymerase II transcription regulatory region sequence-specific DNA binding", "id": "GO:0000977", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000977", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKF8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKF8" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKF8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKF8" } ], "pmid": "" }, { "name": "sequence-specific DNA binding", "id": "GO:0043565", "url": 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"end_pos": 271, "start_aa": "Lys", "end_aa": "His", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 103, "end_pos": 105 }, { "start_pos": 5, "end_pos": 7 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": 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"evidence": [ { "id": "A0A8V0YL41", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL41/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YL41", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL41" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "IDUA", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL41", "locus": { "chromosome": "Z", "start_pos": 54204258, "end_pos": 54269565, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013546", "url": "https://www.ensembl.org/id/ENSGALG00010013546" } ] } } ], "crossref": [ { "id": "A0A8V0YL41", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YL41", "database": "AlphaFoldDB", "categories": [] }, { "id": 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"Protein Classification" ] }, { "id": "IPR051923", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051923", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR12631", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12631", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12631:SF8", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12631:SF8", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01229", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01229", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21200", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21200", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-2024096", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2024096", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": 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"MGLLLWLMVQLGAGSAAYVVYVDVRRAERPLRHFWRSTGFCPPLPHSSADLFDLSKDQEMNLAYISSVPHDGIEQVRIHWLLELITVRMMNEKLYYNFTALDNLMDRLWENKLIPGFELMGNPSGYFPNFEDKEQVVRWRNLVTLLASRYIDRYGLEHVAKWNFETWNEPDHHDFDNVSMTVKGFLNYYDACSEGLRAASTLLKFGGPGDSFHPFPKSPICWSLLCHCYNGTNFFTGETGVRLDYISLHKKGGGRSLYILQQEVETVDQIQKLFPNFASIPIYNDEADPMVGWSVPQLWRADVTYAAMVVKVITQHQNLLISKANNTINYTLLSNDNAFLSYYPHYFTQRTLTARFQMNNTKPPHVQMVRKPVLTVMGLLALLEKQIFAEVNSSEGESTGNNTFGVLASVHTPSELQPSDSWQATLLMYSSEDNSSSSNISTITVNATHFPKLREPVYVTYYLDNNQTNPYQQWKKLGSPDFPSAKQFQQIRDAEDPVVTGPLPFPESGTLTLKQDFPIPSVFLIHICSRPSSVPDQVTGVHFIPLTKGQVVVLWDDGCVNSKCIKTFEVEFSPNGKVYKRINAKDTIFTLYVYSPGSSVSGFYRVRAIDYWGKAGLSSVPVEYVEALK", "length": 629, "header": "tr|A0A8V0YL41-1|A0A8V0YL41_CHICK Isoform 1 of Iduronidase, alpha-L- OS=Gallus gallus OX=9031 GN=IDUA PE=3 SV=1 CANONICAL=A0A8V0YL41-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YKG1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL41/entry#A0A8V0YKG1-1", "sequence": { "sequence": 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"https://www.ensembl.org/id/ENSGALT00010032582.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019303.1", "url": "https://www.ensembl.org/id/ENSGALP00010019303.1" } ] } }, { "isoform_ac": "A0A8V0YL41-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL41/entry#A0A8V0YL41-1", "sequence": { "sequence": "MGLLLWLMVQLGAGSAAYVVYVDVRRAERPLRHFWRSTGFCPPLPHSSADLFDLSKDQEMNLAYISSVPHDGIEQVRIHWLLELITVRMMNEKLYYNFTALDNLMDRLWENKLIPGFELMGNPSGYFPNFEDKEQVVRWRNLVTLLASRYIDRYGLEHVAKWNFETWNEPDHHDFDNVSMTVKGFLNYYDACSEGLRAASTLLKFGGPGDSFHPFPKSPICWSLLCHCYNGTNFFTGETGVRLDYISLHKKGGGRSLYILQQEVETVDQIQKLFPNFASIPIYNDEADPMVGWSVPQLWRADVTYAAMVVKVITQHQNLLISKANNTINYTLLSNDNAFLSYYPHYFTQRTLTARFQMNNTKPPHVQMVRKPVLTVMGLLALLEKQIFAEVNSSEGESTGNNTFGVLASVHTPSELQPSDSWQATLLMYSSEDNSSSSNISTITVNATHFPKLREPVYVTYYLDNNQTNPYQQWKKLGSPDFPSAKQFQQIRDAEDPVVTGPLPFPESGTLTLKQDFPIPSVFLIHICSRPSSVPDQVTGVHFIPLTKGQVVVLWDDGCVNSKCIKTFEVEFSPNGKVYKRINAKDTIFTLYVYSPGSSVSGFYRVRAIDYWGKAGLSSVPVEYVEALK", "length": 629, "header": "tr|A0A8V0YL41-1|A0A8V0YL41_CHICK Isoform 1 of Iduronidase, alpha-L- OS=Gallus gallus OX=9031 GN=IDUA PE=3 SV=1 CANONICAL=A0A8V0YL41-1" }, "locus": { "chromosome": "Z", "start_pos": 54269492, "end_pos": 54225424, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032586.1", "url": "https://www.ensembl.org/id/ENSGALT00010032586.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019306.1", "url": "https://www.ensembl.org/id/ENSGALP00010019306.1" } ] } }, { "isoform_ac": "A0A8V0YMZ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL41/entry#A0A8V0YMZ0-1", "sequence": { "sequence": "MNLAYISSVPHDGIEQVRIHWLLELITVRMMNEKLYYNFTALDNLMDRLWENKLIPGFELMGNPSGYFPNFEDKEQVVRWRNLVTLLASRYIDRYGLEHVAKWNFETWNEPDHHDFDNVSMTVKGFLNYYDACSEGLRAASTLLKFGGPGDSFHPFPKSPICWSLLCHCYNGTNFFTGETGVRLDYISLHKKGGGRSLYILQQEVETVDQIQKLFPNFASIPIYNDEADPMVGWSVPQLWRADVTYAAMVVKVITQHQNLLISKANNTINYTLLSNDNAFLSYYPHYFTQRTLTARFQMNNTKPPHVQMVRKPVLTVMGLLALLGEKQIFAEVNSSEGESTGNNTFGVLASVHTPSELQPSDSWQATLLMYSSEDNSSSSNISTITVNATHFPKLREPVYVTYYLDNNQTNPYQQWKKLGSPDFPSAKQFQQIRDAEDPVVTGPLPFPESGTLTLKQDFPIPSVFLIHICSRPSSVPDQVTGVHFIPLTKGQVVVLWDDGCVNSKCIKTFEVEFSPNGKVYKRINAKDTIFTLYVYSPGSSVSGFYRVRAIDYWGKAGLSSVPVEYRMTKSWHFTACWKVPSWC", "length": 584, "header": "tr|A0A8V0YMZ0-1|A0A8V0YMZ0_CHICK Computationally mapped isoform of Iduronidase, alpha-L- OS=Gallus gallus OX=9031 GN=IDUA PE=3 SV=1 CANONICAL=A0A8V0YL41-1" }, "locus": { "chromosome": "Z", "start_pos": 54266678, "end_pos": 54204622, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032587.1", "url": "https://www.ensembl.org/id/ENSGALT00010032587.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019307.1", "url": "https://www.ensembl.org/id/ENSGALP00010019307.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-2024096", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2024096", "resource": "Reactome", "description": "HS-GAG degradation" }, { "id": "R-GGA-2024101", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2024101", "resource": "Reactome", "description": "CS/DS degradation" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "hydrolase activity, hydrolyzing O-glycosyl compounds", "id": "GO:0004553", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004553", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YL41", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL41" } ], "pmid": "" }, { "name": "L-iduronidase activity", "id": "GO:0003940", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003940", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YL41", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL41" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "carbohydrate metabolic process", "id": "GO:0005975", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005975", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YL41", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL41" } ], "pmid": "" }, { "name": "dermatan sulfate proteoglycan catabolic process", "id": "GO:0030209", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030209", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YL41", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL41" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 177, "end_pos": 179, "annotation": "n_glycosylation_sequon" }, { "start_pos": 230, "end_pos": 232, "annotation": "n_glycosylation_sequon" 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"https://www.uniprot.org/uniprotkb/A0A8V0YKG3", "locus": {} } ], "crossref": [ { "id": "ENSGALG00000042073", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000042073", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd02440", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02440", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "107048987", "url": "https://www.ncbi.nlm.nih.gov/gene/107048987", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "424014", "url": "https://www.ncbi.nlm.nih.gov/gene/424014", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013216", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013216", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029063", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029063", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051052", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051052", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:107048987", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:107048987", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "gga:424014", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424014", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "FSAVHWF", "url": "https://omabrowser.org/oma/group/FSAVHWF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5P5L5", "url": "https://www.orthodb.org/?gene=A0A1D5P5L5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YKG3", "url": "https://www.orthodb.org/?gene=A0A8V0YKG3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR44942", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR44942", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR44942:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR44942:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF08241", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08241", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A1D5P5L5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P5L5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5P5L5-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P5L5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YKG3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKG3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YKG3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKG3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MATQMFEGTQHAAVYLKYRFAPGKELKDIILAYLQEKAPSCTQLAVDVGCGSGQGTAFLADRFAKVVGTDISQAQIQEAKAAPSPPNISYLITRCYSSPPICRVCPAEELPFEDGSVDLLASFTAAHWFDIGKFMNEVKRVLRPGGCVAISTYTIDMSLHYRDCSEKLTQIFREAWDQLLKYSHSRIKHVLEDYKEIFEALPFPDKKRITNIYDKIPMTVAGVVGYLESASPYQVFMKNDPEAAKTLLPGMEKRLLETMGAPSRDTPLEFWVRHVCILGHKEA", "length": 283, "header": "tr|A0A8V0YKG3-1|A0A8V0YKG3_CHICK Isoform 1 of Methyltransferase type 11 domain-containing protein OS=Gallus gallus OX=9031 GN=LOC424014 PE=1 SV=1 CANONICAL=A0A8V0YKG3-1" }, "isoforms": [ { "isoform_ac": "A0A1D5P5L5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKG3/entry#A0A1D5P5L5-1", "sequence": { "sequence": "MATQMFEGTQHAAVYLKYRFAPGKELKDIILAYLQEKAPSCTQLAVDVGCGSGQGTAFLADRFAKVVGTDISQAQIQEAKAAPSPPNISYLVCPAEELPFEDGSVDLLASFTAAHWFDIGKFMNEVKRVLRPGGCVAISTYTIDMSLHYRDCSEKLTQIFREAWDQLLKYSHSRIKHVLEDYKEIFEALPFPDKKRITNIYDKIPMTVAGVVGYLESASPYQVFMKNDPEAAKTLLPGMEKRLLETMGAPSRDTPLEFWVRHVCILGHKEA", "length": 271, "header": "tr|A0A1D5P5L5-1|A0A1D5P5L5_CHICK Computationally mapped isoform of Methyltransferase type 11 domain-containing protein OS=Gallus gallus OX=9031 GN=LOC424014 PE=1 SV=1 CANONICAL=A0A8V0YKG3-1" }, "locus": { "chromosome": "7", "start_pos": 4620303, "end_pos": 4618553, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028771.1", "url": "https://www.ensembl.org/id/ENSGALT00010028771.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016552.1", "url": "https://www.ensembl.org/id/ENSGALP00010016552.1" } ] } }, { "isoform_ac": "A0A8V0YKG3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKG3/entry#A0A8V0YKG3-1", "sequence": { "sequence": "MATQMFEGTQHAAVYLKYRFAPGKELKDIILAYLQEKAPSCTQLAVDVGCGSGQGTAFLADRFAKVVGTDISQAQIQEAKAAPSPPNISYLITRCYSSPPICRVCPAEELPFEDGSVDLLASFTAAHWFDIGKFMNEVKRVLRPGGCVAISTYTIDMSLHYRDCSEKLTQIFREAWDQLLKYSHSRIKHVLEDYKEIFEALPFPDKKRITNIYDKIPMTVAGVVGYLESASPYQVFMKNDPEAAKTLLPGMEKRLLETMGAPSRDTPLEFWVRHVCILGHKEA", "length": 283, "header": "tr|A0A8V0YKG3-1|A0A8V0YKG3_CHICK Isoform 1 of Methyltransferase type 11 domain-containing protein OS=Gallus gallus OX=9031 GN=LOC424014 PE=1 SV=1 CANONICAL=A0A8V0YKG3-1" }, "locus": { "chromosome": "7", "start_pos": 4639446, "end_pos": 4637696, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028851.1", "url": "https://www.ensembl.org/id/ENSGALT00010028851.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016610.1", "url": "https://www.ensembl.org/id/ENSGALP00010016610.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:107048987", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:107048987", "resource": "KEGG Pathway" }, { "id": "gga:424014", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424014", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "Q54JJ5-1", "protein_name": "Methyltransferase type 11 domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MTSEKPKEFQDKFGTVGKSYKTFRPTYTEELYSIIDSYCDSKRDLAIDCGCGSGQATVKLAKYFKKVIGFEPSQGQIENAVKTENVDFRLSPAEKIDLPSGSVDLITVATAVHWFDLPVFYQEAKRLLRDNGSLILFTTGFIQILNNDEAQKINDNFRSGTLGDYWAPIVKYVIDGYVDIKPPFENVERKTISLPKLMSVNDVIGIYSSWSGYASFIKAGNNDVLPGVKENLMSAFKTTDPNAEIVETNFPVYMVLSKK", "length": 259 }, "evidence": [ { "id": "A0A8V0YKG3", "url": "https://omabrowser.org/oma/group/A0A8V0YKG3/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q9M2E3-1", "protein_name": "S-adenosyl-L-methionine-dependent methyltransferases superfamily protein", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MAQLAALSGKQADEYLNARPKYPTIWYKVLAGRTSNHKVAWDVGTGNGQAAIGVAEYYQKVVATDINESQLQRAMKHPKVTYYHTPSSMSDDDLVTLLGGENSIDIIIAAQALHYFDLKRFYPIVKRVLRKQGGIIVVWVYNDLIITPKVDSIMKRLVDSTLPYRNPTMNLAFDGYKTIEFPFKNIRMGTQGRPKALDIPHMLSLDGFLGFLKSWQPLVKAKEQGEDLLTSYMIDEFKEAWGDDEQVKDVHYKAFMLAGKL", "length": 261 }, "evidence": [ { "id": "A0A8V0YKG3", "url": "https://omabrowser.org/oma/group/A0A8V0YKG3/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "S-adenosylmethionine-dependent methyltransferase activity", "id": "GO:0008757", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008757", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKG3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKG3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "methylation", "id": "GO:0032259", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032259", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKG3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKG3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 87, "end_pos": 89, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YKG3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKG3" }, { "id": "PF08241", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08241" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Methyltransferase type 11", "eco_id": "ECO_0000259", "start_pos": 46, "end_pos": 150, "start_aa": "Val", "end_aa": "Ile", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 87, "end_pos": 89 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": 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{ "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YMC1-1", "uniprot_ac": "A0A8V0YMC1", "uniprot_id": "A0A8V0YMC1_CHICK", "mass": { "chemical_mass": 60410.0, "monoisotopic_mass": 60410.0 }, "refseq": { "ac": "XP_046793440", "name": "copine-3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046793440" }, "gene_names": [ { "name": "CPNE3", "type": "recommended", "evidence": [ { "id": "A0A8V0YMC1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMC1" } ] }, { "name": "CPNE3", "type": "synonym", "evidence": [ { "id": "XP_046793440", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046793440" } ] } ], "protein_names": [ { "name": "Copine-3", "type": "recommended", "evidence": [ { "id": "A0A8V0YMC1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMC1/entry#names_and_taxonomy" } ] }, { "name": "Copine III", "type": "synonym", "evidence": [ { "id": "A0A8V0YMC1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMC1/entry#names_and_taxonomy" } ] }, { "name": "copine-3", "type": "synonym", "evidence": [ { "id": "XP_046793440", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046793440" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052533.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_046793440", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046793440" } ] }, { "annotation": "Calcium-dependent phospholipid-binding protein that plays a role in ERBB2-mediated tumor cell migration in response to growth factor heregulin stimulation.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMC1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMC1#function" }, { "database": "UniProtKB", "id": "ARBA00058857", "url": "https://www.uniprot.org/uniprotkb/ARBA00058857#function" }, { "database": "UniProtKB", "id": "A0A8V0YKG4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKG4#function" }, { "database": "UniProtKB", "id": "A0A8V0YS92", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YS92#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMC1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMC1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CPNE3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMC1", "locus": { "chromosome": "2", "start_pos": 122760057, "end_pos": 122734052, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013403", "url": "https://www.ensembl.org/id/ENSGALG00010013403" } ] } } ], "crossref": [ { "id": "A0A8V0YMC1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YMC1", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd01459", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01459", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd04047", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04047", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd04048", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04048", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "420214", "url": "https://www.ncbi.nlm.nih.gov/gene/420214", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000008", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000008", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002035", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002035", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR010734", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010734", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035892", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035892", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036465", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036465", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037768", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037768", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045052", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045052", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "EMAAQCV", "url": "https://omabrowser.org/oma/group/EMAAQCV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YKG4", "url": "https://www.orthodb.org/?gene=A0A8V0YKG4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YMC1", "url": "https://www.orthodb.org/?gene=A0A8V0YMC1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YS92", "url": "https://www.orthodb.org/?gene=A0A8V0YS92", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10857", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10857", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10857:SF22", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10857:SF22", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00168", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00168", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07002", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07002", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-1483206", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1483206", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-6798695", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6798695", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_046793440", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046793440", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YKG4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKG4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YKG4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKG4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YMC1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMC1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YMC1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMC1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YS92", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YS92", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YS92-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YS92-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAQCVTKVELTIACTNLLDKDVGSKSDPLCVLLQNTSGQQWYEVDRTERIKNSLNPKFSKKFLIDYYFELVQKLKFGIYDIDNKTIELSDDDFLGEFECTLGQIVSSKTLTKPLVLKNGRPAGKGSITITAEEVKDNRVVLFEVEARKLDNKDFFGKSDPYLEFHKQTTDGNWVMVHRTEVIKNNLNPVWRPFKISLNSLCYTDMDKPIKVECYDYDSDGSHDVIGSFQTTMSKLKEASRSSPVEFECINEKKRQKKKNYKNSGIVSVKHCEIIVECTFLDYVMGGCQLNFTVGIDFTGSNGDPRSPDSLHYLSPDGVNEYLTAIWSVGMVIQDYDTDKMFPVFGFGAQIPPSYQVSHEFPINFNPSNPFCNGIQGIVDAYRACLPQVRLYGPTNFSPIINHVARFAAAATQQQTASQYFILLIITDGVITDLDQTRTAIVNASKLPMSIIIVGVGGADFDAMEFLDGDNGVLRSSSGEPAVRDIVQFVPFRKFQNSPKEALAQCVLAEIPQQVVNYFSTFKLQPPKNPAANNRGQRE", "length": 539, "header": "tr|A0A8V0YMC1-1|A0A8V0YMC1_CHICK Isoform 1 of Copine-3 OS=Gallus gallus OX=9031 GN=CPNE3 PE=1 SV=1 CANONICAL=A0A8V0YMC1-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YKG4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMC1/entry#A0A8V0YKG4-1", "sequence": { "sequence": "MAAQCVTKVELTIACTNLLDKDVGSKSDPLCVLLQNTSGQQWYEVDRTERIKNSLNPKFSKKFLIDYYFELVQKLKFGIYDIDNKTIELSDDDFLGEFECTLGQIVSSKTLTKPLVLKNGRPAGKGSITITAEEVKDNRVVLFEVEARKLDNKDFFGKSDPYLEFHKQTTDGNWVMVHRTEVIKNNLNPVWRPFKISLNSLCYTDMDKPIKVECYDYDSDGSHDVIGSFQTTMSKLKEASRSSPVEFECINEKKRQKKKNYKNSGIVSVKHCEIIVECTFLDYVMGGCQLNFTVGIDFTGSNGDPRSPDSLHYLSPDGVNEYLTAIWSVGMVIQDYDTDKMFPVFGFGAQIPPSYQVSHEFPINFNPSNPFCNGIQGIVDAYRACLPQVRLYGPTNFSPIINHVARFAAAATQQQTASQYFILLIITDGVITDLDQTRTAIVNASKLPMSIIIVGVGGADFDAMEFLDGDNGVLRSSSGEPAVRDIVQFVPFRKFQNLWHSVSWQKSLSKW", "length": 511, "header": "tr|A0A8V0YKG4-1|A0A8V0YMC1_CHICK Computationally mapped isoform of Copine-3 OS=Gallus gallus OX=9031 GN=CPNE3 PE=1 SV=1 CANONICAL=A0A8V0YMC1-1" }, "locus": { "chromosome": "2", "start_pos": 122757530, "end_pos": 122740860, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032285.1", "url": "https://www.ensembl.org/id/ENSGALT00010032285.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019075.1", "url": "https://www.ensembl.org/id/ENSGALP00010019075.1" } ] } }, { "isoform_ac": "A0A8V0YMC1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMC1/entry#A0A8V0YMC1-1", "sequence": { "sequence": "MAAQCVTKVELTIACTNLLDKDVGSKSDPLCVLLQNTSGQQWYEVDRTERIKNSLNPKFSKKFLIDYYFELVQKLKFGIYDIDNKTIELSDDDFLGEFECTLGQIVSSKTLTKPLVLKNGRPAGKGSITITAEEVKDNRVVLFEVEARKLDNKDFFGKSDPYLEFHKQTTDGNWVMVHRTEVIKNNLNPVWRPFKISLNSLCYTDMDKPIKVECYDYDSDGSHDVIGSFQTTMSKLKEASRSSPVEFECINEKKRQKKKNYKNSGIVSVKHCEIIVECTFLDYVMGGCQLNFTVGIDFTGSNGDPRSPDSLHYLSPDGVNEYLTAIWSVGMVIQDYDTDKMFPVFGFGAQIPPSYQVSHEFPINFNPSNPFCNGIQGIVDAYRACLPQVRLYGPTNFSPIINHVARFAAAATQQQTASQYFILLIITDGVITDLDQTRTAIVNASKLPMSIIIVGVGGADFDAMEFLDGDNGVLRSSSGEPAVRDIVQFVPFRKFQNSPKEALAQCVLAEIPQQVVNYFSTFKLQPPKNPAANNRGQRE", "length": 539, "header": "tr|A0A8V0YMC1-1|A0A8V0YMC1_CHICK Isoform 1 of Copine-3 OS=Gallus gallus OX=9031 GN=CPNE3 PE=1 SV=1 CANONICAL=A0A8V0YMC1-1" }, "locus": { "chromosome": "2", "start_pos": 122757849, "end_pos": 122740860, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032281.1", "url": "https://www.ensembl.org/id/ENSGALT00010032281.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019071.1", "url": "https://www.ensembl.org/id/ENSGALP00010019071.1" } ] } }, { "isoform_ac": "A0A8V0YS92-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMC1/entry#A0A8V0YS92-1", "sequence": { "sequence": "MAAQCVTKVELTIACTNLLDKDVGSKSDPLCVLLQNTSGQQWYEVDRTERIKNSLNPKFSKKFLIDYYFELVQKLKFGIYDIDNKTIELSDDDFLGEFECTLGQIVSSKTLTKPLVLKNGRPAGKGSITITAEEVKDNRVVLFEVEARKLDNKDFFGKSDPYLEFHKQTTDGNWVMVHRTEVIKNNLNPVWRPFKISLNSLCYTDMDKPIKVECYDYDSDGSHDVIGSFQTTMSKLKEASRSSPVEFECINEKKRQKKKNYKNSGIVSVKHCEIIVECTFLDYVMGGCQLNFTVGIDFTGSNGDPRSPDSLHYLSPDGVNEYLTAIWSVGMVIQDYDTDKMFPVFGFGAQIPPSYQVSHEFPINFNPSNPFCNGIQGIVDAYRACLPQVRLYGPTNFSPIINHVARFAAAATQQQTASQYFILLIITDGVITDLDQTRTAIVNASKLPMSIIIVGVGGADFDAMEFLDGDNGVLRSSSGEPAVRDIVQFVPFRKFQNSPKEALAQCVLAEIPQQVVNYFSTFKLQPPKNPAAK", "length": 533, "header": "tr|A0A8V0YS92-1|A0A8V0YS92_CHICK Computationally mapped isoform of Copine-3 OS=Gallus gallus OX=9031 GN=CPNE3 PE=1 SV=1 CANONICAL=A0A8V0YMC1-1" }, "locus": { "chromosome": "2", "start_pos": 122757583, "end_pos": 122740860, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032274.1", "url": "https://www.ensembl.org/id/ENSGALT00010032274.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019064.1", "url": "https://www.ensembl.org/id/ENSGALP00010019064.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-1483206", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1483206", "resource": "Reactome", "description": "Glycerophospholipid biosynthesis" }, { "id": "R-GGA-6798695", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6798695", "resource": "Reactome", "description": "Neutrophil degranulation" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A4X1UBQ4-1", "protein_name": "Copine-3", "gene_name": "CPNE3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAAQCVTKVELNISCDNLLDKDVGSKSDPLCVLFLNTSGQQWYEVERTERIKNCLNPKFSKTFIIDYYFEVVQKLKFGIYDIDNKTIELSDDDFLGEFECTLGQIVSSKKLTRPLVLKNGRPAGKGSITISAEEIKDNRVVLFEMEARKLDNKDLFGKSDPYLEFHKQTSDGNWLMVHRTEVIKNNLNPVWRPFKISLNSLCYGDMDKTIKVECYDYDNDGSHDLIGTFQTTMTKLKEASRNSPIEFECINEKKKQKKKSYKNSGIISVKQCEITVECTFLDYVMGGCQLNFTVGVDFTGSNGDPRSPNSLHYISPNGVNEYLTAIWSVGLVIQDYDADKMFPAFGFGAQIPPQWQVSHEFPINFNPSNPYCNGIQGIIEAYRACLPQIKLYGPTNFSPIINHVAKFAAAATQQHTASQYFVLLIITDGVITDLDETRQAIVNAAKLPMSIIIVGVGGADFSAMEFLDADGGSLRSPSGEVAIRDIVQFVPFRQFQNAPKEALAQCVLAEIPQQVVGYFNAYKLLPPKNPAAK", "length": 533 }, "evidence": [ { "id": "A0A8V0YMC1", "url": "https://omabrowser.org/oma/group/A0A8V0YMC1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "D3ZLA3-1", "protein_name": "Copine-3", "gene_name": "Cpne3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGRVANSLPHTHTHHTHTHTHTHTHTHTHTHTHTHTHNHLGPSHKLRPRPGRARTPPTSPAPPVPVKPLRSHRLAVLLAGSPPSLDFLGDLVAEDMAAQCVTKVELNISCNSLLDTDLTSKSDPLCVLFLNTSGQQWYEVERTERIKNSLNPKFSKTFVIDYYFEVVQKLKFGIYDIDNKTIELSDDDFLGECEVTLGQIVSSKKLTRPLVLKNGKPAGQGSITILAEEIKDNRVVLFEMEARKLDNKDLFGKSDPYLEFHKQTSDGHWLMVHRTEVIKNNLNPMWKPFKISLNSLCYGDMDKTIKVECYDYDNDGSHDLIGTFQTTMTKLKEASRSSPVEFECINEKKRQKKKSYKNSGVIVVKHCEITVECTFLDYIMGGCQLNFTVGVDFTGSNGDPSSPDSLHYISPNGVNEYLTAIWSVGLVVQDYDADKMFPAFGFGAQVPPQWQVSHEFPMNFNPSNPYCNGIQGIIEAYRTCLPQIRLYGPTNFSPIINHVARFAAAATQQQTASQYFVLLIITDGVITDLDQTRQAIVSAAKLPMSIIIVGVGGADFSAMEFLDGDNGSLRAPSGEVAIRDIVQFVPFRQFQNAPKEALAQCVLAEIPQQVVGYFNTYRLLPPKNPAVK", "length": 628 }, "evidence": [ { "id": "A0A8V0YMC1", "url": "https://omabrowser.org/oma/group/A0A8V0YMC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1Q9D2-1", "protein_name": "Copine-3", "gene_name": "cpne3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MATACVSKVELTVSCENLLDMDVGSKSDPLCVLLMNTSGNQWFEVDRTERVKNCLNPKFAKKFVVDYHFEIVQKLRFAVYDIDNKTIDLSDDDFLGELECSLGQIVSSSRLSRPLLLKNKKPAGKGVIMISAEEIKDNRVVNFEVEARKLDNKDFFGKSDPFLEFYRQTETGWQLAHRTEVVKNNLNPCWRPFKIPLRSLCAGDMEKPIKVECHDYDNDGSHDLIGIFETNMKRLEAASRSAPAEFECINSKKKQKKKSYKNSGVVSVKVCQITREYTFLDYIMGGCQINFTVGIDFTGSNGDPRSPDSLHYISPQGVNEYLSAIWSVGLVVQDYDSDKMFPAFGFGAQIPPSWQVSHEFPLNFNPTNPFCAGVEGVIEAYRMCLPQVKLYGPTNFAPIINHMARFAQQALQQKTASQYFVLLIITDGVITDMDQTRGAIVAASRLPMSIIIVGVGKADFTDMEILDGDDGRLKSVTGEPAVRDIVQFVPFRKFQNSPKEELAKCVLAEVPGQVVTFFNMMKYPPPNSNTPVDASNGVKN", "length": 540 }, "evidence": [ { "id": "A0A8V0YMC1", "url": "https://omabrowser.org/oma/group/A0A8V0YMC1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "G3I9G3-1", "protein_name": "Copine-3", "gene_name": "Cpne3", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAAQCVTKVELHVSCDNLLDTDLTSKSDPLCVLFLNTSGQQWYEVERTERIKNSLSPKFSKTFIIDYYFEVVQKLKFGIYDIDNKTIELSDDDFLGEFEVTLGQIVSSKKLTRPLVLRNGRPAGKGTITISAEEIKDNRVVLFEMEARKLDNKDLFGKSDPYLEFHKQTSDGNWLMVHRTEVIKNNLNPVWKPFKISLNSLCYGDMDKTIKVECYDYDNDGSHDLIGTFQTTMTKLKEASRNSPVEYECINEKKRQKKKSYKNSGVISVKHCEITVECTFLDYIMGGCQLNFTVGVDFTGSNGDPSSSDSLHYISPNGVNEYLTAIWSVGLVIQDYDADKMFPAFGFGAQVPPQWQVSHEFPMNFNPSNPYCNGIQGIIEAYRTCLPQIRLYGPTNFSPIINHVARFAAAATQQQTASQYFVLLIITDGVITDLDETRHAIVNASKLPMSIIIVGVGGADFSAMEFLDGDGGSLRSPSGEVAIRDIVQFVPFRQFQNAPKEALAQCVLAEIPQQVVGYFNTYKLLPPKNPAAK", "length": 533 }, "evidence": [ { "id": "A0A8V0YMC1", "url": "https://omabrowser.org/oma/group/A0A8V0YMC1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "O75131-1", "protein_name": "Copine-3", "gene_name": "CPNE3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAQCVTKVALNVSCANLLDKDIGSKSDPLCVLFLNTSGQQWYEVERTERIKNCLNPQFSKTFIIDYYFEVVQKLKFGVYDIDNKTIELSDDDFLGECECTLGQIVSSKKLTRPLVMKTGRPAGKGSITISAEEIKDNRVVLFEMEARKLDNKDLFGKSDPYLEFHKQTSDGNWLMVHRTEVVKNNLNPVWRPFKISLNSLCYGDMDKTIKVECYDYDNDGSHDLIGTFQTTMTKLKEASRSSPVEFECINEKKRQKKKSYKNSGVISVKQCEITVECTFLDYIMGGCQLNFTVGVDFTGSNGDPRSPDSLHYISPNGVNEYLTALWSVGLVIQDYDADKMFPAFGFGAQIPPQWQVSHEFPMNFNPSNPYCNGIQGIVEAYRSCLPQIKLYGPTNFSPIINHVARFAAAATQQQTASQYFVLLIITDGVITDLDETRQAIVNASRLPMSIIIVGVGGADFSAMEFLDGDGGSLRSPLGEVAIRDIVQFVPFRQFQNAPKEALAQCVLAEIPQQVVGYFNTYKLLPPKNPATKQQKQ", "length": 537 }, "evidence": [ { "id": "A0A8V0YMC1", "url": "https://omabrowser.org/oma/group/A0A8V0YMC1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q5XQC7-1", "protein_name": "Protein BONZAI 3", "gene_name": "BON3", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MGGCLSGDVKGGKQAIGGVQQRPTSSTIANNAAHNDAVDFFFRSRGQYPLFSQIELTLSASNLLDCDITSKSDPMAVMYLRKKDGRLEEIGRTEVILNNLNPKWIEKITVSFQFEAVQTLVFHVYDVDTRYHNVPVKTLKLKDQDFLGEGTCVLSEIMTRQNRTLTLTLTGNVRAGVNRNLGTLSIQAEETVASKTVAEINFRCVNLDNKDLFSKSDPFLRISRVVETSAAVPICRTEVVDNNLNPMWRPVCLTMQQFGSKDTPLVIECLDFNTSGNHELIGKTEKSVAELERLCLQKEAANFVYPSLSHGRNKVLKGQLIVDRYVEKVQYSFLDYISSGFELNFMVAVDFTASNGDPRTPSSLHYIDPSGRLNSYQQAIMEVGEVIQFYDSDKRFPAWGFGGRTSDGSVSHAFNLNGASYGDEVVGVEGIMVAYASALRNVSLAGPTLFSNVVDKAAHTASQSLSQNSPKYFVLLIITDGVLTDMAGTVDALVRASDLPLSVLIVGVGNTDFKQMEMLDADNGRRLESSTGRIATRDIVQFVPMKDIHSGLVSVVQALLEELPGQFLTYVRSRKINPIGAPAI", "length": 584 }, "evidence": [ { "id": "A0A8V0YMC1", "url": "https://omabrowser.org/oma/group/A0A8V0YMC1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q7YXU4-1", "protein_name": "Copine-A", "gene_name": "cpnA", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNLKPPTSKVELRIKCHKILDKDTLSKSDPRASVYEKDRAGQFRLIGKTETIQNQLNPEFKTPIVIDYRFEEIQVLKFEIHDVDKNDEDFIGDASCTLTSILSKPGQTVCLQLLTKSGKHAGSMTVIAEEIKNTLQTIKFNLIGKKFDKKDLFGAGCDPYLIISRKVPSTNTFVKIYESQVQKGTLNPVFSGIEMKLEELCGGDMQREIKFEFYDWDRIGKHDYIGEFHTNAQELLQPNQAFNVINSHKQEKKSGYKNSGTVSVSDAVIEREYNFLEYIMGGCQMNLIVGIDCTASNGDSNDPNSLHYKNAQGLNQYANAICSVGNVIVPYTTTPLIPVYGFGGIMPGQSEVSHCFPMTLNASNTLCCGVNGVLDCYYDNISKIQLHGPTYFAPLINMAARYASQGQSQSNQKYTILMIITDGEILDADNTIDAIVKSSGLPLSIIIVGVGNANFTNMNILDGDDAALQSGGVRAERDIVQFVAMRDYLNRPNELAAEVLREIPTQFLSFMKKYKFRPNPPPPPPPVIIGAPPQYDNPTTTTTATSPSTGIDLNKGSNVGLNLTKTESSPSPSGGAGIDLNKGSVVDITKGVSNVSLEKN", "length": 600 }, "evidence": [ { "id": "A0A8V0YMC1", "url": "https://omabrowser.org/oma/group/A0A8V0YMC1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q8BT60-1", "protein_name": "Copine-3", "gene_name": "Cpne3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAQCVTKVELNVSCNNLLDADVTSKSDPLCVLFLNTSGHQWYEVERTERIKNSLNPKFSKTFVIDYYFEVVQKLKFGIYDIDNKTIELSDDDFLGECEVTLGQIVSSKKLTRPLVLKNGKPAGKGSITISAEEIKDNRVVLFEMEARKLDNKDLFGKSDPYLEFHKQTSDGHWLMVHRTEVIKNNLNPMWKPFKISLNSLCYGDMDKTIKVECYDYDNDGSHDLIGTFQTTMTKLKEASRSSPVEYECINEKKRQKKKSYKNSGVISVKHCEITVECTFLDYIMGGCQLNFTVGVDFTGSNGDPSSPDSLHYISPNGVNEYLTAIWSVGLVIQDYDADKMFPAFGFGAQVPPQWQVSHEFPMNFNPSNPYCNGIQGIVEAYRTCLPQIRLYGPTNFSPIINHVARFAAAATQQQTASQYFVLLIITDGVITDLDETRQAIVNAAKLPMSIIIVGVGGADFSAMEFLDGDGGSLRAPSGEVAIRDIVQFVPFRQFQNAPKEALAQCVLAEIPQQVVGYFNTYKLLPPKNPAVK", "length": 533 }, "evidence": [ { "id": "A0A8V0YMC1", "url": "https://omabrowser.org/oma/group/A0A8V0YMC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMC1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMC1" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMC1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMC1" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMC1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMC1" } ], "pmid": "" }, { "name": "focal adhesion", "id": "GO:0005925", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005925", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMC1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMC1" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMC1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMC1" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMC1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMC1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMC1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMC1" } ], "pmid": "" }, { "name": "calcium-dependent phospholipid binding", "id": "GO:0005544", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005544", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMC1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMC1" } ], "pmid": "" }, { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMC1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMC1" } ], "pmid": "" }, { "name": "calcium-dependent protein binding", "id": "GO:0048306", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048306", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMC1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMC1" } ], "pmid": "" }, { "name": "receptor tyrosine kinase binding", "id": "GO:0030971", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030971", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMC1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMC1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "cellular response to calcium ion", "id": "GO:0071277", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071277", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMC1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMC1" } ], "pmid": "" }, { "name": "positive regulation of cell migration", "id": "GO:0030335", "url": 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"end_pos": 445, "annotation": "n_glycosylation_sequon" }, { "start_pos": 84, "end_pos": 86, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YMC1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMC1" }, { "id": "PS50004", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50004" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2", "eco_id": "ECO_0000259", "start_pos": 1, "end_pos": 115, "start_aa": "Met", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], 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"field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YKH5-1", "uniprot_ac": "A0A8V0YKH5", "uniprot_id": "A0A8V0YKH5_CHICK", "mass": { "chemical_mass": 81258.0, "monoisotopic_mass": 81258.0 }, "refseq": { "ac": "XP_015132933", "name": "myogenesis-regulating glycosidase isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015132933" }, "gene_names": [ { "name": "LOC431653", "type": "recommended", "evidence": [ { "id": "A0A8V0YKH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKH5" } ] }, { "name": "LOC431653", "type": "synonym", "evidence": [ { "id": "XP_015132933", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015132933" } ] } ], "protein_names": [ { "name": "Myogenesis-regulating glycosidase", "type": "recommended", "evidence": [ { "id": "A0A8V0YKH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKH5/entry#names_and_taxonomy" } ] }, { "name": "myogenesis-regulating glycosidase isoform X2", "type": "synonym", "evidence": [ { "id": "XP_015132933", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015132933" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052572.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015132933.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015132933", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015132933" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKH5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKH5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LOC431653", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKH5", "locus": {} } ], "crossref": [ { "id": "cd06592", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06592", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "431653", "url": "https://www.ncbi.nlm.nih.gov/gene/431653", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000322", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000322", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013780", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013780", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017853", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017853", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048395", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048395", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050985", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050985", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:431653", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:431653", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PTHR43053", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43053", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR43053:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43053:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01055", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01055", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21365", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21365", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015132933", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015132933", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YKH5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKH5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YKH5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKH5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MESQITHRKEKHGNIQTGEDKEIHWTRNFTPVKQKPSKELRPMLGAVTLGLILFIAAVVAWCYYTVSLRKAERLKTELMDLRADGFVIRNQHGEVVFRLAFRSGSLDLESCSKEGEILSCTRSDRGPLNFFIQTVKPKDTVMCYRVRWEELAAGPAVEHTMFWEDAHWYGGSEMSTQHWPIRLAGYQEPVPYVTSDVYSFRDSFGGILERYWLSSKAAAIKINDSVPFHLGFNATERSLFFQARYKDSPYKPPPGQQPFPELSYRVCVGSDVTSIHKYMVRRYFNKPFKIPAENAFRYPIWSTWALYKKDIDQDKVLHFARNIKKYRFNCSHIEIDDMYTQAYGDFDFDPVKFPNVTEMFAKLREDGFKVTLWIHPFIHVYSSNFGVGIERQLFIKEPSGRLPAMVEWWNGIGAILDFTNPAARDWFQSHLRQLRHKYGISSFKFDAGETSYLPKQFSTFRPLSDPSIWSRRYTEMAIPFYELAEVRVGYQSQNISCFFRIIDRDSVWGYELGLKSLIPTVLTISMLGYPFVLPDMIGGNFLPNKTDGAVEIPDRELYIRWLELSAFMPSMQFSIPPWLYDKEVVEIAQKFTELHESLVAPLLLELAREVTDTGDPIIRPIWWISPRDEATHRIDSQFLIGDTLMVAPVLEMGKQERDVYLPVGKWRSYKRELFEKTPVLLTDYPVDLDEVAYFLWVS", "length": 698, "header": "tr|A0A8V0YKH5-1|A0A8V0YKH5_CHICK Isoform 1 of Myogenesis-regulating glycosidase OS=Gallus gallus OX=9031 GN=LOC431653 PE=3 SV=1 CANONICAL=A0A8V0YKH5-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YKH5-1", "url": 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"ac": "NP_001269200", "name": "transmembrane protein 174", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001269200" }, "gene_names": [ { "name": "TMEM174", "type": "recommended", "evidence": [ { "id": "A0A8V0YKI0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKI0" } ] }, { "name": "TMEM174", "type": "synonym", "evidence": [ { "id": "NP_001269200", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001269200" } ] } ], "protein_names": [ { "name": "Transmembrane protein 174", "type": "synonym", "evidence": [ { "id": "A0A8V0YKI0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKI0/entry#names_and_taxonomy" } ] }, { "name": "transmembrane protein 174", "type": "synonym", "evidence": [ { "id": "NP_001269200", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001269200" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: SRR13267656.5675.1, DR410673.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992323, SAMEA103992393 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000089.1. On Dec 3, 2021 this sequence version replaced NP_001269200.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001269200", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001269200" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKI0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKI0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TMEM174", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKI0", "locus": { "chromosome": "Z", "start_pos": 25450038, "end_pos": 25454699, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012023", "url": "https://www.ensembl.org/id/ENSGALG00010012023" } ] } } ], "crossref": [ { "id": "A0A8V0YKI0", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YKI0", "database": 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"http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31020:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15029", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15029", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001269200", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001269200", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YKI0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKI0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YKI0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKI0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEQNNSSVEDFSLNVFSVTPYPPSRSDALVSDGDKAGATLLFSGVFLGLVGITFTVMGWIKYDGLTHLEWTQLLGPILLSVGVTFILIAVCKFNMLTCKPCKEREENMLDIDQSSSGQSFVFTGINQPITFHGATVVQYIPPPYPALDSAAASPGYLHPVLSCCGAVSPGVSPIPSPSSAHFCPAYSLDNPAFTWDESCASYLAESTRNTRPEDSSDEPEELLEDPCEELSPPRYEEIYPLSS", "length": 243, "header": "tr|A0A8V0YKI0-1|A0A8V0YKI0_CHICK Isoform 1 of Transmembrane protein 174 OS=Gallus gallus OX=9031 GN=TMEM174 PE=4 SV=1 CANONICAL=A0A8V0YKI0-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YKI0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKI0/entry#A0A8V0YKI0-1", "sequence": { "sequence": "MEQNNSSVEDFSLNVFSVTPYPPSRSDALVSDGDKAGATLLFSGVFLGLVGITFTVMGWIKYDGLTHLEWTQLLGPILLSVGVTFILIAVCKFNMLTCKPCKEREENMLDIDQSSSGQSFVFTGINQPITFHGATVVQYIPPPYPALDSAAASPGYLHPVLSCCGAVSPGVSPIPSPSSAHFCPAYSLDNPAFTWDESCASYLAESTRNTRPEDSSDEPEELLEDPCEELSPPRYEEIYPLSS", "length": 243, "header": "tr|A0A8V0YKI0-1|A0A8V0YKI0_CHICK Isoform 1 of Transmembrane protein 174 OS=Gallus gallus OX=9031 GN=TMEM174 PE=4 SV=1 CANONICAL=A0A8V0YKI0-1" }, "locus": { "chromosome": "Z", "start_pos": 25454664, "end_pos": 25452788, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028791.1", "url": "https://www.ensembl.org/id/ENSGALT00010028791.1" }, { "database": "Ensembl Peptide", "id": 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"protein_name": "Transmembrane protein 174", "gene_name": "TMEM174", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRTMEQGHNRVEDFPLNVFSVTPYTPSTADIQVSDDDKAGATLLFSGIFLGLVGITFTIMGWIKYQGVSHFEWTQLLGPILLSVGVTFILIAVCKFKMLSCQLCKESEERVPDLEQTAGGQSFVFTGINQPITFHGATVVQYIPPPYGSQEPLGMTTTYLQPVVSPCGLVPPGGLAAAMPSPPQYYTIYPPENAAFVHDQDYPSFVDAGDDRSSPDAEQLEETQLGDEDSTCFSPPPYEEICSLPR", "length": 246 }, "evidence": [ { "id": "A0A8V0YKI0", "url": "https://omabrowser.org/oma/group/A0A8V0YKI0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3I0G3-1", "protein_name": "Transmembrane protein 174", "gene_name": "Tmem174", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MEHNTSSSEDFPLNVFSVTPYTPSTADIQVSDDDKAGATLLFSGIFLGLVGITFTVMGWIKYQGVSHFEWTQLLGPILLSVGVTFILIAVCKFKMLSCQLCTESEERVLDSDQTSGGQSFVFTGINQPITFHGATVVQYIPPPYASQEPLGMNAAYLQPMMNPCGLVPSSGAVAAAPSPPQYYTIYPQDNAAFVENEGYPPFVAVGNDRPSSDADQLEGMQMEEEDCVHFSPPPYEEIYALPR", "length": 243 }, "evidence": [ { "id": "A0A8V0YKI0", "url": "https://omabrowser.org/oma/group/A0A8V0YKI0/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q68FU0-1", "protein_name": "Transmembrane protein 174", "gene_name": "Tmem174", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEQSSNRPEDFPLNVFSVTPYTPSTADIQVSDDDKAGATLLFSGIFLGLVGITFTVMGWIKYQGVSHFEWTQLLGPILLSVGVTFILISVCKFKMLSCQLCTDNEERVLDSDQTSGGQSFVFTGINQPITFHGATVVQYIPPPYGSQEPLGMNTTYLQPMMNPCGLVPSSGAVAATPSPPQYYTIYPQDNAAFVESEGFSPFVGAGHDRPSSDADQLEGTQMGEEERVCFSPPPYEEIYALPR", "length": 243 }, "evidence": [ { "id": "A0A8V0YKI0", "url": "https://omabrowser.org/oma/group/A0A8V0YKI0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8WUU8-1", "protein_name": "Transmembrane protein 174", "gene_name": "TMEM174", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEQGSGRLEDFPVNVFSVTPYTPSTADIQVSDDDKAGATLLFSGIFLGLVGITFTVMGWIKYQGVSHFEWTQLLGPVLLSVGVTFILIAVCKFKMLSCQLCKESEERVPDSEQTPGGPSFVFTGINQPITFHGATVVQYIPPPYGSPEPMGINTSYLQSVVSPCGLITSGGAAAAMSSPPQYYTIYPQDNSAFVVDEGCLSFTDGGNHRPNPDVDQLEETQLEEEACACFSPPPYEEIYSLPR", "length": 243 }, "evidence": [ { "id": "A0A8V0YKI0", "url": "https://omabrowser.org/oma/group/A0A8V0YKI0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9DCX7-1", "protein_name": "Transmembrane protein 174", "gene_name": "Tmem174", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEHSSNRPEDFPLNVFSVTPYTPSTADIQVSDDDKAGATLLFSGIFLGLVGITFTVMGWIKYQGVSHFEWTQLLGPILLSVGVTFILIAVCKFKMLSCQLCSDNEERVPDSDQTSGGQSFVFTGINQPITFHGATVVQYIPPPYGSQEPLGMNATYLQPMMNPCGLIPPSGAAAAAPSPPQYYTIYPQDNAAFVESEGFSPFVGTGYDRPDSDADQLEGTELEEEDCVCFSPPPYEEIYALPR", "length": 243 }, "evidence": [ { "id": "A0A8V0YKI0", "url": "https://omabrowser.org/oma/group/A0A8V0YKI0/", "database": "OMA" } ], "glygen_name": 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"start_pos": 4, "end_pos": 6, "annotation": "n_glycosylation_sequon" }, { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 4, "end_pos": 6 }, { "start_pos": 5, "end_pos": 7 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", 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}, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YKJ1-1", "uniprot_ac": "A0A8V0YKJ1", "uniprot_id": "A0A8V0YKJ1_CHICK", "mass": { "chemical_mass": 65417.0, "monoisotopic_mass": 65417.0 }, "refseq": {}, "gene_names": [ { "name": "PGM2", "type": "recommended", "evidence": [ { "id": "A0A8V0YKJ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKJ1" } ] } ], "protein_names": [ { "name": "Phosphoglucomutase 2", "type": "synonym", "evidence": [ { "id": "A0A8V0YKJ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKJ1/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKJ1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PGM2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKJ1", "locus": { "chromosome": "4", "start_pos": 69293827, "end_pos": 69343654, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010015310", "url": "https://www.ensembl.org/id/ENSGALG00010015310" } ] } } ], "crossref": [ { "id": "A0A8V0YKJ1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YKJ1", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd05799", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05799", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "426435", "url": "https://www.ncbi.nlm.nih.gov/gene/426435", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR005841", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005841", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005844", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005844", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005845", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005845", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005846", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005846", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016055", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016055", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016066", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016066", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036900", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036900", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:426435", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:426435", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "GYCVDPE", "url": "https://omabrowser.org/oma/group/GYCVDPE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YKJ1", "url": "https://www.orthodb.org/?gene=A0A8V0YKJ1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YKL1", "url": "https://www.orthodb.org/?gene=A0A8V0YKL1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YKL6", "url": "https://www.orthodb.org/?gene=A0A8V0YKL6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YRZ4", "url": "https://www.orthodb.org/?gene=A0A8V0YRZ4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YS76", "url": "https://www.orthodb.org/?gene=A0A8V0YS76", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YYP7", "url": "https://www.orthodb.org/?gene=A0A8V0YYP7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45745", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45745", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45745:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45745:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02878", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02878", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02879", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02879", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02880", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02880", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-6798695", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6798695", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-71336", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-71336", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YKJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKJ1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YKJ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKJ1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YKL1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKL1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YKL1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKL1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YKL6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKL6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YKL6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKL6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YRZ4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRZ4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YRZ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRZ4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YS76", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YS76", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YS76-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YS76-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YYP7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYP7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YYP7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYP7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNPKTSAIVKELVAEGNVEELQKYFGSRMEFGTAGLRAAMGAGISHMNDLTIIQTTQGFCRYLEKNFSDLKNRGVVIGFDARAHLSSGGSSKRFARLAANTFISQGVPVYLFSDVTPTPFVPYTVTHLKLCAGIMVTASHNPKQDNGYKVYWENGAQIISPHDKGISQAIEENKEPWPQAWDDKQIDSSALLHDPYATINKEYFKDIQKQCFHRNINKETNLKFVHTSVHGVGHKFVQLAFKAFDLRPPFAVPEQKDPDPEFPTVKYPNPEEGKGVLTLSFALAEKDGAKIILANDPDADRLAVAEKQESGEWKVFSGNELGALLGWWIFTCWKKQNRDACAIKDVYMLSSTVSSKILRAIALKEGFHFEETLTGFKWMGNRAKQLMDQGKAVLFAFEEAIGYMCCPAVLDKDGVSAAVITAEMASFLATRNLSLSQQLKAVYDEYGFHITKASYFICHDPKVIQQLFDNLRNYDGKDTYPKSCGRFKVSGIRDLTTGYDSSQPDLKAILPTSKSSQMITFTFANGGVATMRTSGTEPKIKYYSELCAPPGNSDVEQLKKELDELVSALEKHFFQPEKNNLQRKTE", "length": 586, "header": "tr|A0A8V0YKJ1-1|A0A8V0YKJ1_CHICK Isoform 1 of Phosphoglucomutase 2 OS=Gallus gallus OX=9031 GN=PGM2 PE=1 SV=1 CANONICAL=A0A8V0YKJ1-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YKJ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKJ1/entry#A0A8V0YKJ1-1", "sequence": { "sequence": "MNPKTSAIVKELVAEGNVEELQKYFGSRMEFGTAGLRAAMGAGISHMNDLTIIQTTQGFCRYLEKNFSDLKNRGVVIGFDARAHLSSGGSSKRFARLAANTFISQGVPVYLFSDVTPTPFVPYTVTHLKLCAGIMVTASHNPKQDNGYKVYWENGAQIISPHDKGISQAIEENKEPWPQAWDDKQIDSSALLHDPYATINKEYFKDIQKQCFHRNINKETNLKFVHTSVHGVGHKFVQLAFKAFDLRPPFAVPEQKDPDPEFPTVKYPNPEEGKGVLTLSFALAEKDGAKIILANDPDADRLAVAEKQESGEWKVFSGNELGALLGWWIFTCWKKQNRDACAIKDVYMLSSTVSSKILRAIALKEGFHFEETLTGFKWMGNRAKQLMDQGKAVLFAFEEAIGYMCCPAVLDKDGVSAAVITAEMASFLATRNLSLSQQLKAVYDEYGFHITKASYFICHDPKVIQQLFDNLRNYDGKDTYPKSCGRFKVSGIRDLTTGYDSSQPDLKAILPTSKSSQMITFTFANGGVATMRTSGTEPKIKYYSELCAPPGNSDVEQLKKELDELVSALEKHFFQPEKNNLQRKTE", "length": 586, "header": "tr|A0A8V0YKJ1-1|A0A8V0YKJ1_CHICK Isoform 1 of Phosphoglucomutase 2 OS=Gallus gallus OX=9031 GN=PGM2 PE=1 SV=1 CANONICAL=A0A8V0YKJ1-1" }, "locus": { "chromosome": "4", "start_pos": 69341099, "end_pos": 69315882, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010036830.1", "url": "https://www.ensembl.org/id/ENSGALT00010036830.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021457.1", "url": "https://www.ensembl.org/id/ENSGALP00010021457.1" } ] } }, { "isoform_ac": "A0A8V0YKL1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKJ1/entry#A0A8V0YKL1-1", "sequence": { "sequence": "MAAQGSAGDAALRREAEQWLQWDQNPKTSAIVKELVAEGNVEELQKYFGSRMEFGTAGLRAAMGAGISHMNDLTIIQTTQGFCRYLEKNFSDLKNRGVVIGFDARAHLSSGGSSKRFARLAANTFISQGVPVYLFSDVTPTPFVPYTVTHLKLCAGIMVTASHNPKQDNGYKVYWENGAQIISPHDKGISQAIEENKEPWPQAWDDKQIDSSALLHDPYATINKEYFKDIQKQCFHRNINKETNLKFVHTSVHGVGHKFVQLAFKAFDLRPPFAVPEQKDPDPEFPTVKYPNPEEGKGVLTLSFALAEKDGAKIILANDPDADRLAVAEKQESGEWKVFSGNELGALLGWWIFTCWKKQNRDACAIKDVYMLSSTVSSKILRAIALKEGFHFEETLTGFKWMGNRAKQLMDQGKAVLFAFEEAIGYMCCPAVLDKDGVSAAVITAEMASFLATRNLSLSQQLKAVYDEYGFHITKASYFICHDPKVIQQLFDNLRNYDGKDTYPKSCGRFKVSGIRDLTTGYDSSQPDLKAILPTSKSSQMITFTFANGGVATMRTSGTEPKIKYYSELCAPPGNSDVEQLKKELDELVSALEKHFFQPEKNNLQRKTE", "length": 609, "header": "tr|A0A8V0YKL1-1|A0A8V0YKL1_CHICK Computationally mapped isoform of Phosphoglucomutase 2 OS=Gallus gallus OX=9031 GN=PGM2 PE=1 SV=1 CANONICAL=A0A8V0YKJ1-1" }, "locus": { "chromosome": "4", "start_pos": 69332632, "end_pos": 69315882, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010036871.1", "url": "https://www.ensembl.org/id/ENSGALT00010036871.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021478.1", "url": "https://www.ensembl.org/id/ENSGALP00010021478.1" } ] } }, { "isoform_ac": "A0A8V0YKL6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKJ1/entry#A0A8V0YKL6-1", "sequence": { "sequence": "MAAQGSAGDAALRREAEQWLQWDQNPKTSAIVKELVAEGNVEELQKYFGSRMEFGTAGLRAAMGAGISHMNDLTIIQTTQGFCRYLEKNFSDLKNRGVVIGFDARAHLSSGGSSKRFARLAANTFISQGVPVYLFSDVTPTPFVVYWENGAQIISPHDKGISQAIEENKEPWPQAWDDKQIDSSALLHDPYATINKEYFKDIQKQCFHRNINKETNLKFVHTSVHGVGHKFVQLAFKAFDLRPPFAVPEQKDPDPEFPTVKYPNPEEGKGVLTLSFALAEKDGAKIILANDPDADRLAVAEKQESGEWKVFSGNELGALLGWWIFTCWKKQNRDACAIKDVYMLSSTVSSKILRAIALKEGFHFEETLTGFKWMGNRAKQLMDQGKAVLFAFEEAIGYMCCPAVLDKDGVSAAVITAEMASFLATRNLSLSQQLKAVYDEYGFHITKASYFICHDPKVIQQLFDNLRNYDGKDTYPKSCGRFKVSGIRDLTTGYDSSQPDLKAILPTSKSSQMITFTFANGGVATMRTSGTEPKIKYYSELCAPPGNSDVEQLKKELDELVSALEKHFFQPEKNNLQRKTE", "length": 581, "header": "tr|A0A8V0YKL6-1|A0A8V0YKL6_CHICK Computationally mapped isoform of Phosphoglucomutase 2 OS=Gallus gallus OX=9031 GN=PGM2 PE=1 SV=1 CANONICAL=A0A8V0YKJ1-1" }, "locus": { "chromosome": "4", "start_pos": 69332632, "end_pos": 69315882, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010036884.1", "url": "https://www.ensembl.org/id/ENSGALT00010036884.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021483.1", "url": "https://www.ensembl.org/id/ENSGALP00010021483.1" } ] } }, { "isoform_ac": "A0A8V0YRZ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKJ1/entry#A0A8V0YRZ4-1", "sequence": { "sequence": "MAAQGSAGDAALRREAEQWLQWDQNPKTSAIVKELVAEGNVEELQKYFGSRMEFGTAGLRAAMGAGISHMNDLTIIQTTQGFCRYLEKNFSDLKNRGVVIGFDARAHLSSGGSSKRFARLAANTFISQGVPVYLFSDVTPTPFVPYTVTHLKLCAGIMVTASHNPKQDNGYKVYWENGAQIISPHDKGISQAWDDKQIDSSALLHDPYATINKEYFKDIQKQCFHRNINKETNLKFVHTSVHGVGHKFVQLAFKAFDLRPPFAVPEQKDPDPEFPTVKYPNPEEGKGVLTLSFALAEKDGAKIILANDPDADRLAVAEKQESGEWKVFSGNELGALLGWWIFTCWKKQNRDACAIKDVYMLSSTVSSKILRAIALKEGFHFEETLTGFKWMGNRAKQLMDQGKAVLFAFEEAIGYMCCPAVLDKDGVSAAVITAEMASFLATRNLSLSQQLKAVYDEYGFHITKASYFICHDPKVIQQLFDNLRNYDGKDTYPKSCGRFKVSGIRDLTTGYDSSQPDLKAILPTSKSSQMITFTFANGGVATMRTSGTEPKIKYYSELCAPPGNSDVEQLKKELDELVSALEKHFFQPEKNNLQRKTE", "length": 598, "header": "tr|A0A8V0YRZ4-1|A0A8V0YRZ4_CHICK Computationally mapped isoform of Phosphoglucomutase 2 OS=Gallus gallus OX=9031 GN=PGM2 PE=1 SV=1 CANONICAL=A0A8V0YKJ1-1" }, "locus": { "chromosome": "4", "start_pos": 69332632, "end_pos": 69315882, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010036875.1", "url": "https://www.ensembl.org/id/ENSGALT00010036875.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021480.1", "url": "https://www.ensembl.org/id/ENSGALP00010021480.1" } ] } }, { "isoform_ac": "A0A8V0YS76-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKJ1/entry#A0A8V0YS76-1", "sequence": { "sequence": "MAAQGSAGDAALRREAEQWLQWDQNPKTSAIVKELVAEGNVEELQKYFGSRMEFGTAGLRAAMGAGISHMNDLTIIQTTQGFCRYLEKNFSDLKNRGVVIGFDARAHLSSGGSSKRFARLAANTFISQGVPVYLFSDVTPTPFVPYTVTHLKLCAGIMVTASHNPKQDNGYKVYWENGAQIISPHDKGISQAIEENKEPWPQAWDDKQIDSSALLHDPYATINKEYFKDIQKQCFHRNINKETNLKFVHTSVHGVGHKFVQLAFKAFDLRPPFAVPEQKDPDPEFPTVKYPNPEEGKGVLTLSFALAEKDGAKIILANDPDADRLAVAEKQESGEWKVFSGNELGALLGWWIFTCWKKQNRDACAIKDVYMLSSTVSSKILRAIALKEGFHFESVGFWYMCCPAVLDKDGVSAAVITAEMASFLATRNLSLSQQLKAVYDEYGFHITKASYFICHDPKVIQQLFDNLRNYDGKDTYPKSCGRFKVSGIRDLTTGYDSSQPDLKAILPTSKSSQMITFTFANGGVATMRTSGTEPKIKYYSELCAPPGNSDVEQLKKELDELVSALEKHFFQPEKNNLQRKTE", "length": 582, "header": "tr|A0A8V0YS76-1|A0A8V0YS76_CHICK Computationally mapped isoform of Phosphoglucomutase 2 OS=Gallus gallus OX=9031 GN=PGM2 PE=1 SV=1 CANONICAL=A0A8V0YKJ1-1" }, "locus": { "chromosome": "4", "start_pos": 69332632, "end_pos": 69315882, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010036880.1", "url": "https://www.ensembl.org/id/ENSGALT00010036880.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021482.1", "url": "https://www.ensembl.org/id/ENSGALP00010021482.1" } ] } }, { "isoform_ac": "A0A8V0YYP7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKJ1/entry#A0A8V0YYP7-1", "sequence": { "sequence": "MEFGTAGLRAAMGAGISHMNDLTIIQTTQGFCRYLEKNFSDLKNRGVVIGFDARAHLSSGGSSKRFARLAANTFISQGVPVYLFSDVTPTPFVPYTVTHLKLCAGIMVTASHNPKQDNGYKVYWENGAQIISPHDKGISQAIEENKEPWPQAWDDKQIDSSALLHDPYATINKEYFKDIQKQCFHRNINKETNLKFVHTSVHGVGHKFVQLAFKAFDLRPPFAVPEQKDPDPEFPTVKYPNPEEGKGVLTLSFALAEKDGAKIILANDPDADRLAVAEKQESGEWKVFSGNELGALLGWWIFTCWKKQNRDACAIKDVYMLSSTVSSKILRAIALKEGFHFEETLTGFKWMGNRAKQLMDQGKAVLFAFEEAIGYMCCPAVLDKDGVSAAVITAEMASFLATRNLSLSQQLKAVYDEYGFHITKASYFICHDPKVIQQLFDNLRNYDGKDTYPKSCGRFKVSGIRDLTTGYDSSQPDLKAILPTSKSSQMITFTFANGGVATMRTSGTEPKIKYYSELCAPPGNSDVEQLKKELDELVSALEKHFFQPEKNNLQRKTE", "length": 558, "header": "tr|A0A8V0YYP7-1|A0A8V0YYP7_CHICK Computationally mapped isoform of Phosphoglucomutase 2 OS=Gallus gallus OX=9031 GN=PGM2 PE=1 SV=1 CANONICAL=A0A8V0YKJ1-1" }, "locus": { "chromosome": "4", "start_pos": 69329545, "end_pos": 69315882, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010036843.1", "url": "https://www.ensembl.org/id/ENSGALT00010036843.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021463.1", "url": "https://www.ensembl.org/id/ENSGALP00010021463.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 118, "start_aa": "Thr", "end_pos": 118, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr118", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:426435", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:426435", "resource": "KEGG Pathway" }, { "id": "R-GGA-6798695", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6798695", "resource": "Reactome", "description": "Neutrophil degranulation" }, { "id": "R-GGA-71336", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-71336", "resource": "Reactome", "description": "Pentose phosphate pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "F7FLB2-1", "protein_name": "Phosphoglucomutase 2", "gene_name": "Pgm2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEDNGRLLERVTGPPPLGCGSDRMAAATPTQTPAPEASGLGMDARLDQETAQWLRWDRNPLTSESVKQLLAEGNKEELEKCFGARMEFGTAGLRAPMGAGISRMNDLTIIQTTQGFCRYLEKQFSDLKQRGVVISFDGRAHPASGGSSRRFARLAATAFISQGVPVHLFSDITPTPFVPYTVSHLKLCAGIMITASHNPKQDNGYKVYWDNGAQIISPHDRGISQAIEENLEPWPQAWDESLIDSSSLLHNPSTSISNDYFEDLKKYCFHRTVNRESQVKFVHTSVHGVGHEFVQSAFKAFDLNPPEAVPQQKDPDPEFPTVKYPNPEEGKGVLTLSFELADKIKAKIVLANDPDADRLAVAEKQDSGEWRVFSGNELGALLGWWLFTSWKEKNQGQSNLKDTYMLSSTVSSKILRAIALKEGFHFEETLTGFKWMGNRAKQLIDQGKTVLFAFEEAIGYMCCPFVLDKDGVSAAVISAELVSFLATKNLSLSLQLKAIYLEYGYHITTASYFICHDQGTIQKLFENLRNYDGKNKYPKTCGKFEISAVRDLTTGYDSNQPDKKAVLPTSKSSQMITFTFVNGGVATMRTSGTEPKIKYYAELCAPPGNSDPEQLKRELDELVGAIEEHFFQPQKYNLQPKAE", "length": 643 }, "evidence": [ { "id": "A0A8V0YKJ1", "url": "https://omabrowser.org/oma/group/A0A8V0YKJ1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3IFE7-1", "protein_name": "Phosphoglucomutase-2", "gene_name": "Pgm2", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAEAMATPIPAPGVSGSGMDTRLEQETAQWLRWDRNPLTSESVKQLIAEGNNEELQKCFGARMEFGTAGLRAPMGAGISRMNDLTIIQTTQGFCRYLEKQFSDLKQRGVVISFDARAHPASGGSSRRFARLAATAFISQGVPVHLFSDITPTPFVPYTVSHLKLCAGIMITASHNPKQDNGYKVYWDNGAQIISPHDRGISQAIEENLEPWPQAWDESLIDSSSLLHNPSTSISHDYFEDLKKYCFHRSVNRESDVKFVHTSVHGVGHEFVQLAFKAFDLAPPEAVPEQKDPDPEFPTVKYPNPEEGKGVLTLSFALADKIKAKIILANDPDADRLAVAEKQDSGEWRVFSGNELGALLGWWLFTSWKEKNRDRSTLKDTYMLSSTVSSKILRAIALKEGFHFEETLTGFKWMGNRTKQLVDQGKTVLFAFEEAIGYMCCPFVLDKDGVSAAVISAELASFLATKNLSLSQQLKAIYVEYGYHITKASYFICHDQGTIQKLFGNLRNYDGKNNYPKTCGRFEISAIRDLTTGYDDSQPDKKAILPTSKSSQMITFTFANGGVATIRTSGTEPKIKYYAELCAPPGNSDLEQLKKELDELVSAIEENFFQPQKYNLQPKSE", "length": 620 }, "evidence": [ { "id": "A0A8V0YKJ1", "url": "https://omabrowser.org/oma/group/A0A8V0YKJ1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q03262-1", "protein_name": "Phosphoribomutase", "gene_name": "PRM15", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MLQGILETVPSDLKDPISLWFKQDRNPKTIEEVTALCKKSDWNELHKRFDSRIQFGTAGLRSQMQAGFSRMNTLVVIQASQGLATYVRQQFPDNLVAVVGHDHRFHSKEFARATAAAFLLKGFKVHYLNPDHEFVHTPLVPFAVDKLKASVGVMITASHNPKMDNGYKVYYSNGCQIIPPHDHAISDSIDANLEPWANVWDFDDVLNKALKQGKLMYSREEMLKLYLEEVSKNLVEINPLKLEVKAKPWFVYTPMHGVGFDIFSTIVKKTLCLVEGKDYLCVPEQQNPDPSFPTVGFPNPEEKGALDIGINLAEKHDIDLLVANDPDADRFSVAVKDMQSGEWRQLTGNEIGFLFAFYEYQKYKSMDKEFQHVHPLAMLNSTVSSQMIKKMAEIEGFHYEDTLTGFKWIGNRAILLEKKGYYVPFGFEEAIGYMFPAMEHDKDGISASIVFLQAYCKWKIDHNLDPLNVLENGFKKYGVFKEYNGYYVVPNPTVTKDIFDYIRNVYTPEGASYPSSIGEEIEVLYYRDLTTGYQSDTINHKPTLPVDPTSQMITVSARPSNGSENEHIRFTIRGSGTEPKLKVYIEACANEEQRASFLAKLTWNVLRREWFRPDEMNIVTKF", "length": 622 }, "evidence": [ { "id": "A0A8V0YKJ1", "url": "https://omabrowser.org/oma/group/A0A8V0YKJ1/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q7TSV4-1", "protein_name": "Phosphopentomutase", "gene_name": "Pgm2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAATPTETPAPEGSGLGMDARLDQETAQWLRWDQNPLTSESVKQLIAGGNKEELRKCFGARMEFGTAGLRAPMGAGISRMNDLTIIQTTQGFCRYLEKQFSDLKQRGVVISFDARAHPASGGSSRRFARLAATAFITQGVPVYLFSDITPTPFVPYTVSHLKLCAGIMITASHNPKQDNGYKVYWDNGAQIISPHDRGISQAIEENLEPWPQAWEESLVDSSPLLHNPSASIGNDYFEDLKKYCFHRTVNKESKVKFVHTSVHGVGHEFVQLAFKAFDLAPPEAVPQQKDPDPEFPTVKYPNPEEGKGVLTLSFALADKIKAKIVLANDPDADRLAVAEKQDSGEWRVFSGNELGALLGWWLFTSWKEKNQDQSNLKDTYMLSSTVSSKILRAIALKEGFHFEETLTGFKWMGNRAQQLGDQGKTVLFAFEEAIGYMCCPFVLDKDGVSAAVICAELASFLATKNLSLSQQLNAIYVEYGYHITTASYFICHDQGTIQNLFGNLRNYDGKNNYPKMCGKFEISAIRDLTTGYDDSQPDKKAVLPTSKSSQMITFTFANGGVATMRTSGTEPKIKYYAELCAPPGNSDPEHLKKELDELVGAIEEHFFQPQKYNLQPKAE", "length": 620 }, "evidence": [ { "id": "A0A8V0YKJ1", "url": "https://omabrowser.org/oma/group/A0A8V0YKJ1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "magnesium ion binding", "id": "GO:0000287", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000287", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKJ1" } ], "pmid": "" }, { "name": "intramolecular phosphotransferase activity", "id": "GO:0016868", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016868", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKJ1" } ], "pmid": "" }, { "name": "phosphoglucomutase activity", "id": "GO:0004614", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004614", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKJ1" } ], "pmid": "" }, { "name": "phosphopentomutase activity", "id": "GO:0008973", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008973", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKJ1" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKJ1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKJ1" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKJ1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "glucose metabolic process", "id": "GO:0006006", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006006", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKJ1" } ], "pmid": "" }, { "name": "glycogen biosynthetic process", "id": "GO:0005978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005978", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKJ1" } ], "pmid": "" }, { "name": "purine ribonucleoside salvage", "id": "GO:0006166", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006166", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKJ1" } ], "pmid": "" }, { "name": "glycogen catabolic process", "id": "GO:0005980", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005980", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKJ1" } ], "pmid": "" }, { "name": "carbohydrate metabolic process", "id": "GO:0005975", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005975", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKJ1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 432, "end_pos": 434, "annotation": "n_glycosylation_sequon" }, { "start_pos": 66, "end_pos": 68, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YKJ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKJ1" }, { "id": "PF02878", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02878" }, { "id": "PF02879", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02879" }, { "id": "PF02880", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02880" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Alpha-D-phosphohexomutase alpha/beta/alpha", "eco_id": "ECO_0000259", "start_pos": 29, "end_pos": 175, "start_aa": "Met", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 118 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 432, "end_pos": 434 }, { "start_pos": 66, "end_pos": 68 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YKL2-1", "uniprot_ac": "A0A8V0YKL2", "uniprot_id": "A0A8V0YKL2_CHICK", "mass": { "chemical_mass": 13271.0, "monoisotopic_mass": 13271.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Uncharacterized protein", "type": "synonym", "evidence": [ { "id": "A0A8V0YKL2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKL2/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKL2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKL2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKL2", "locus": {} } ], "crossref": [ { "id": "A0A8V0YKL2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YKL2", "database": "AlphaFoldDB", "categories": [] }, { "id": "A0A8V0YKL2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKL2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YKL2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKL2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSFSTSPAGWDWGPPGCLRGHYPPHAREGAGGPVSCPETLQPSELPPYLSAGATPGAEPSRRPQRHAGEASGHRADSGQVQAHSPPRASFLDDLFPRWPSHRCFHREESEGWRALLEAPSCVP", "length": 123, "header": "tr|A0A8V0YKL2-1|A0A8V0YKL2_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0YKL2-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YKL2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKL2/entry#A0A8V0YKL2-1", "sequence": { "sequence": 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Classification", "Other" ] }, { "id": "A0A8V0YKL9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKL9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YKL9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKL9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAPPAASGIPSIAPSLGPTAVWLGNRSDLGDVQALASRDLPTTTVTAGNNNKPEHLEYVAFVLVPVFFIMGLLGILICHVLKKKGYRCTTEAEEVEEEEKPDEKIEMNETAHENSDTVGQIINYIMKNEANADVLKAMVADSSVFEPESPMSPNAPGSPTSPGSPLSPGAASLKHNCKGHHLHTVGGVIEKDVCSRCSHKRWHHIKPAHKSKEHRRSRLGEVTVLSVGRVTKVEHKSNSKERKSLMSVTGVEGLNGDMPATPVKQEAKEAPATPVKEGTQERRSSE", "length": 286, "header": "tr|A0A8V0YKL9-1|A0A8V0YKL9_CHICK Isoform 1 of RELT like 1 OS=Gallus gallus OX=9031 GN=RELL1 PE=3 SV=1 CANONICAL=A0A8V0YKL9-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YKL9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKL9/entry#A0A8V0YKL9-1", "sequence": { "sequence": "MAPPAASGIPSIAPSLGPTAVWLGNRSDLGDVQALASRDLPTTTVTAGNNNKPEHLEYVAFVLVPVFFIMGLLGILICHVLKKKGYRCTTEAEEVEEEEKPDEKIEMNETAHENSDTVGQIINYIMKNEANADVLKAMVADSSVFEPESPMSPNAPGSPTSPGSPLSPGAASLKHNCKGHHLHTVGGVIEKDVCSRCSHKRWHHIKPAHKSKEHRRSRLGEVTVLSVGRVTKVEHKSNSKERKSLMSVTGVEGLNGDMPATPVKQEAKEAPATPVKEGTQERRSSE", "length": 286, "header": "tr|A0A8V0YKL9-1|A0A8V0YKL9_CHICK Isoform 1 of RELT like 1 OS=Gallus gallus OX=9031 GN=RELL1 PE=3 SV=1 CANONICAL=A0A8V0YKL9-1" }, "locus": { "chromosome": "4", "start_pos": 69366840, "end_pos": 69351205, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010036900.1", "url": "https://www.ensembl.org/id/ENSGALT00010036900.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021488.1", "url": "https://www.ensembl.org/id/ENSGALP00010021488.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKL9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKL9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "positive regulation of p38MAPK cascade", "id": "GO:1900745", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1900745", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKL9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKL9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 108, "end_pos": 110, "annotation": "n_glycosylation_sequon" }, { "start_pos": 25, "end_pos": 27, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 108, "end_pos": 110 }, { "start_pos": 25, "end_pos": 27 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YKM2-1", "uniprot_ac": "A0A8V0YKM2", "uniprot_id": "A0A8V0YKM2_CHICK", "mass": { "chemical_mass": 81894.0, "monoisotopic_mass": 81894.0 }, "refseq": {}, "gene_names": [ { "name": "MCTP1", "type": "recommended", "evidence": [ { "id": "A0A8V0YKM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKM2" } ] } ], "protein_names": [ { "name": "Multiple C2 and transmembrane domain-containing protein 1", "type": "recommended", "evidence": [ { "id": "A0A8V0YKM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKM2/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKM2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKM2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MCTP1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKM2", "locus": { "chromosome": "Z", "start_pos": 58613032, "end_pos": 58381384, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013149", "url": "https://www.ensembl.org/id/ENSGALG00010013149" } ] } } ], "crossref": [ { "id": "A0A8V0YKM2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YKM2", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd04042", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04042", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd08376", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd08376", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd08377", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd08377", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000008", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000008", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013583", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013583", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035892", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035892", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YKM2", "url": "https://www.orthodb.org/?gene=A0A8V0YKM2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45911", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45911", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45911:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45911:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00168", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00168", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08372", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08372", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YKM2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKM2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YKM2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKM2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNTYGSIGVYSPLRKCMKKTVLLRGVSALNTYSEKTSLVGPSNVDFPSGDPGMYQLDITLRRGQNLAARDRGGTSDPYVKFKLGGKEVFRSKTIHKNLNPVWEEKTCILIENPREPLYIKVFDYDFGLQDDFIGSAFLNLASLELNRQTDVTLSLKDPHYPDHDLGNILLSVLLAPREEQREVFQTQSLRLSDLHRKSQLWRGIVSITLIEGRELKAMDANGLSDPYVKFRLGHQKYKSKIMPKTLNPQWREQFDFHLYEERGGIIDITVWDKDAGKKDDFIGRCQVDLSTLSKEQTHKLEMLLEEGEGCLVLLVTLTASAAVTISDLSVNSLEDPKEREEILKRYSLMRMFHNMKDVGFLQVKVIRAEALMAADVTGKSDPFCVVELNNDRLLTHTVYKNLNPEWNKIFTFNIKDIHSVLEVTVYDEDRDRSADFLGKVAIPLLSIQNGEQKAYVLKNKQLTGPTKGVIYLEIDVIFNAVKASIRTLMPKEQKYIEEENRLSKQLLLRNFIRMKRCVMVLINAAYYVNSCFDWDSPPRSLAAFLVVEDMLEDEEEEDDRDDKSLPRSDKITWLWYCTSGILQEDSEKKGFMDKLYAIQEVCVSVQNILDEVASFGERIKNTFNWTVPFLSWLAIVALCVFTVILYFIPLRYIVLVWGINKFTKKLRSPYAIDNNELLDFLSRVPSDVQVVQYHELKQDPSHSPSKRKKNNPG", "length": 713, "header": "tr|A0A8V0YKM2-1|A0A8V0YKM2_CHICK Isoform 1 of Multiple C2 and transmembrane domain-containing protein 1 OS=Gallus gallus OX=9031 GN=MCTP1 PE=1 SV=1 CANONICAL=A0A8V0YKM2-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YKM2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKM2/entry#A0A8V0YKM2-1", "sequence": { "sequence": "MNTYGSIGVYSPLRKCMKKTVLLRGVSALNTYSEKTSLVGPSNVDFPSGDPGMYQLDITLRRGQNLAARDRGGTSDPYVKFKLGGKEVFRSKTIHKNLNPVWEEKTCILIENPREPLYIKVFDYDFGLQDDFIGSAFLNLASLELNRQTDVTLSLKDPHYPDHDLGNILLSVLLAPREEQREVFQTQSLRLSDLHRKSQLWRGIVSITLIEGRELKAMDANGLSDPYVKFRLGHQKYKSKIMPKTLNPQWREQFDFHLYEERGGIIDITVWDKDAGKKDDFIGRCQVDLSTLSKEQTHKLEMLLEEGEGCLVLLVTLTASAAVTISDLSVNSLEDPKEREEILKRYSLMRMFHNMKDVGFLQVKVIRAEALMAADVTGKSDPFCVVELNNDRLLTHTVYKNLNPEWNKIFTFNIKDIHSVLEVTVYDEDRDRSADFLGKVAIPLLSIQNGEQKAYVLKNKQLTGPTKGVIYLEIDVIFNAVKASIRTLMPKEQKYIEEENRLSKQLLLRNFIRMKRCVMVLINAAYYVNSCFDWDSPPRSLAAFLVVEDMLEDEEEEDDRDDKSLPRSDKITWLWYCTSGILQEDSEKKGFMDKLYAIQEVCVSVQNILDEVASFGERIKNTFNWTVPFLSWLAIVALCVFTVILYFIPLRYIVLVWGINKFTKKLRSPYAIDNNELLDFLSRVPSDVQVVQYHELKQDPSHSPSKRKKNNPG", "length": 713, "header": "tr|A0A8V0YKM2-1|A0A8V0YKM2_CHICK Isoform 1 of Multiple C2 and transmembrane domain-containing protein 1 OS=Gallus gallus OX=9031 GN=MCTP1 PE=1 SV=1 CANONICAL=A0A8V0YKM2-1" }, "locus": { "chromosome": "Z", "start_pos": 58611063, "end_pos": 58381428, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031517.1", "url": "https://www.ensembl.org/id/ENSGALT00010031517.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018408.1", "url": "https://www.ensembl.org/id/ENSGALP00010018408.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 466, "start_aa": "Thr", "end_pos": 466, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr466", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "recycling endosome", "id": "GO:0055037", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055037", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKM2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKM2" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKM2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKM2" } ], "pmid": "" }, { "name": "synaptic vesicle membrane", "id": "GO:0030672", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030672", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKM2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKM2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKM2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKM2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "regulation of neurotransmitter secretion", "id": "GO:0046928", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046928", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKM2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKM2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 624, "end_pos": 626, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YKM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKM2" }, { "id": "PS50004", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50004" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2", "eco_id": "ECO_0000259", "start_pos": 35, "end_pos": 153, "start_aa": "Lys", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 466 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 624, "end_pos": 626 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YKP7-1", "uniprot_ac": "A0A8V0YKP7", "uniprot_id": "A0A8V0YKP7_CHICK", "mass": { "chemical_mass": 5815.0, "monoisotopic_mass": 5815.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Uncharacterized protein", "type": "synonym", "evidence": [ { "id": "A0A8V0YKP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKP7/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKP7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKP7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKP7", "locus": {} } ], "crossref": [ { "id": "A0A8V0YKP7", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YKP7", "database": "AlphaFoldDB", "categories": [] }, { "id": "A0A8V0YKP7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKP7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YKP7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKP7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "IFKTDPYRPDRFNCANCGILFVPNVKSHSWVTVIMREKAWHIVRPTTIR", "length": 49, "header": "tr|A0A8V0YKP7-1|A0A8V0YKP7_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0YKP7-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YKP7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKP7/entry#A0A8V0YKP7-1", "sequence": { "sequence": "IFKTDPYRPDRFNCANCGILFVPNVKSHSWVTVIMREKAWHIVRPTTIR", "length": 49, "header": "tr|A0A8V0YKP7-1|A0A8V0YKP7_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0YKP7-1" }, "locus": { "chromosome": "1", "start_pos": 140178269, "end_pos": 140177307, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031562.1", "url": "https://www.ensembl.org/id/ENSGALT00010031562.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018438.1", "url": "https://www.ensembl.org/id/ENSGALP00010018438.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YKQ9-1", "uniprot_ac": "A0A8V0YKQ9", "uniprot_id": "A0A8V0YKQ9_CHICK", "mass": { "chemical_mass": 108372.0, "monoisotopic_mass": 108372.0 }, "refseq": {}, "gene_names": [ { "name": "FAM13B", "type": "recommended", "evidence": [ { "id": "A0A8V0YKQ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKQ9" } ] } ], "protein_names": [ { "name": "Protein FAM13B", "type": "recommended", "evidence": [ { "id": "A0A8V0YKQ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKQ9/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKQ9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKQ9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "FAM13B", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKQ9", "locus": { "chromosome": "13", "start_pos": 14006156, "end_pos": 13965469, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010015409", "url": "https://www.ensembl.org/id/ENSGALG00010015409" } ] } } ], "crossref": [ { "id": "A0A8V0YKQ9", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YKQ9", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd04393", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04393", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000198", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000198", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008936", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008936", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039102", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039102", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR059029", "url": "https://www.ebi.ac.uk/interpro/entry/IPR059029", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YKQ9", "url": "https://www.orthodb.org/?gene=A0A8V0YKQ9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YKR3", "url": "https://www.orthodb.org/?gene=A0A8V0YKR3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YS45", "url": "https://www.orthodb.org/?gene=A0A8V0YS45", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YYV8", "url": "https://www.orthodb.org/?gene=A0A8V0YYV8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15904", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15904", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15904:SF16", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15904:SF16", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00620", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00620", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF26116", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF26116", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-9013148", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013148", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9013149", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013149", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YKQ9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKQ9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YKQ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKQ9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YKR3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKR3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YKR3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKR3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YS45", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YS45", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YS45-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YS45-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YYV8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYV8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YYV8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYV8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRKSSSPSLSNCNSVLANKIFGIPLDELQQEGQPDNEVPFIVRHVVDYIEEHGGLEQEGLFQVNGNAETVEWLRQRYDNGEDVDLVKEADVPSAISLLRFFLQELPEPVIPGSLHIHLMQLSQDYNNEDEFGRKLRFLLQQLPPVNYSLLKFLCKFLANVASHHEEIWSASSLAAVFGPDVFHIYTDVEDLKEQEIVSRIMAGLLENYYEFFENEEEDFSSTNDLSSITEQINDLLEEEEDIKLEQSEELPEDGTEKPIERPAVVHLDVTGSISDSRSVTASTSAHISPISILPASADILERTIRAAVEQHLFDLQSSLDNDLKQIQQHRLGCNNDANNPSGDEEGSNNQNDVIENNDIGSSENVEDCSEVSVSTDLGNEDMKHDTVTEEEESVQVLALPSAEPADGLLKQCDKDADVDGENNSERQNSILVDGNDRISSEMFLDSSTKACDLNANTDSEVSGDGDVFVPEEALSVQVPRLDLKNASDGDKWEAPCPITFPLIDFKTMHLQREGEDPFPAFKSWQEDSESGEAQLSPQAGRMTNHPLEEDCHPILSHRSLDFGQSQRFLHDPETLDSSSKALSFVRTRRASFSSKDDKREDKTPYQLVKKLQKKIKQFEEQFEKERNSKPSYSDIAANPKVLKWMTDLTKLRKQIKDAKQKSSDGEFIPQTRPRSNTLPKSFGSSLDQEDEENGDEMRIVQKEKKPTKEATLELILKRLKEKRVERCLPEDIKKMTKDHLVEEKTSLQKSLLFYESQHGRPVTREERHIVKPLYDRYRLVKQMLTRASITPILGSPSTKRRGQMLQPIIEGETAHFFEEIKEEEEESDGLSADLNDILKSAVQTQSVLSPVENSESDVEDGQEKLTRDLRLSSTRAASMPELLEQLWKARAEKKKLRKTLREFEEEFYQQNGRNVQKEDRVPMLDEYREYKKIKAKLRLLEVLISKQDSSKSI", "length": 953, "header": "tr|A0A8V0YKQ9-1|A0A8V0YKQ9_CHICK Isoform 1 of Protein FAM13B OS=Gallus gallus OX=9031 GN=FAM13B PE=3 SV=1 CANONICAL=A0A8V0YKQ9-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YKQ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKQ9/entry#A0A8V0YKQ9-1", "sequence": { "sequence": "MRKSSSPSLSNCNSVLANKIFGIPLDELQQEGQPDNEVPFIVRHVVDYIEEHGGLEQEGLFQVNGNAETVEWLRQRYDNGEDVDLVKEADVPSAISLLRFFLQELPEPVIPGSLHIHLMQLSQDYNNEDEFGRKLRFLLQQLPPVNYSLLKFLCKFLANVASHHEEIWSASSLAAVFGPDVFHIYTDVEDLKEQEIVSRIMAGLLENYYEFFENEEEDFSSTNDLSSITEQINDLLEEEEDIKLEQSEELPEDGTEKPIERPAVVHLDVTGSISDSRSVTASTSAHISPISILPASADILERTIRAAVEQHLFDLQSSLDNDLKQIQQHRLGCNNDANNPSGDEEGSNNQNDVIENNDIGSSENVEDCSEVSVSTDLGNEDMKHDTVTEEEESVQVLALPSAEPADGLLKQCDKDADVDGENNSERQNSILVDGNDRISSEMFLDSSTKACDLNANTDSEVSGDGDVFVPEEALSVQVPRLDLKNASDGDKWEAPCPITFPLIDFKTMHLQREGEDPFPAFKSWQEDSESGEAQLSPQAGRMTNHPLEEDCHPILSHRSLDFGQSQRFLHDPETLDSSSKALSFVRTRRASFSSKDDKREDKTPYQLVKKLQKKIKQFEEQFEKERNSKPSYSDIAANPKVLKWMTDLTKLRKQIKDAKQKSSDGEFIPQTRPRSNTLPKSFGSSLDQEDEENGDEMRIVQKEKKPTKEATLELILKRLKEKRVERCLPEDIKKMTKDHLVEEKTSLQKSLLFYESQHGRPVTREERHIVKPLYDRYRLVKQMLTRASITPILGSPSTKRRGQMLQPIIEGETAHFFEEIKEEEEESDGLSADLNDILKSAVQTQSVLSPVENSESDVEDGQEKLTRDLRLSSTRAASMPELLEQLWKARAEKKKLRKTLREFEEEFYQQNGRNVQKEDRVPMLDEYREYKKIKAKLRLLEVLISKQDSSKSI", "length": 953, "header": "tr|A0A8V0YKQ9-1|A0A8V0YKQ9_CHICK Isoform 1 of Protein FAM13B OS=Gallus gallus OX=9031 GN=FAM13B PE=3 SV=1 CANONICAL=A0A8V0YKQ9-1" }, "locus": { "chromosome": "13", "start_pos": 14006055, "end_pos": 13976022, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010037012.1", "url": "https://www.ensembl.org/id/ENSGALT00010037012.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021529.1", "url": "https://www.ensembl.org/id/ENSGALP00010021529.1" } ] } }, { "isoform_ac": "A0A8V0YKR3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKQ9/entry#A0A8V0YKR3-1", "sequence": { "sequence": "MRKSSSPSLSNCNSVLANKIFGIPLDELQQEGQPDNEVPFIVRHVVDYIEEHGGLEQEGLFQVNGNAETVEWLRQRYDNGEDVDLVKEADVPSAISLLRFFLQELPEPVIPGSLHIHLMQLSQDYNNEDEFGRKLRFLLQQLPPVNYSLLKFLCKFLANVASHHEEIWSASSLAAVFGPDVFHIYTDVEDLKEQEIVSRIMAGLLENYYEFFENEEEDFSSTNDLSSITEQINDLLEEEEDIKLEQSEELPEDGTEKPIERPAVVHLDVTGSISDSRSVTASTSAHISPISILPASADILERTIRAAVEQHLFDLQSSLDNDLKQIQQHRLGCNNDANNPSGDEEGSNNQNDVIENNDIGSSENVEDCSEVSVSTDLGNEDMKHDTVTEEEESVQVLALPSAEPADGLLKQCDKDADVDGENNSERQNSILVDGNDRISSEMFLDSSTKACDLNANTDSEVSGDGDVFVPEEALSVQVPRLDLKNASDGDKWEDPFPAFKSWQEDSESGEAQLSPQAGRMTNHPLEEDCHPILSHRSLDFGQSQRFLHDPETLDSSSKALSFVRTRRASFSSKDDKREDKTPYQLVKKLQKKIKQFEEQFEKERNSKPSYSDIAANPKVLKWMTDLTKLRKQIKDAKQKSSDGEFIPQTRPRSNTLPKSFGSSLDQEDEENGDEMRIVQKEKKPTKEATLELILKRLKEKRVERCLPEDIKKMTKDHLVEEKTSLQKSLLFYESQHGRPVTREERHIVKPLYDRYRLVKQMLTRASITPILGSPSTKRRGQMLQPIIEGETAHFFEEIKEEEEESDGLSADLNDILKSAVQTQSVLSPVENSESDVEDGQEKLTRDLRLSSTRAASMPELLEQLWKARAEKKKLRKTLREFEEEFYQQNGRNVQKEDRVPMLDEYREYKKIKAKLRLLEVLISKQDSSKSI", "length": 931, "header": "tr|A0A8V0YKR3-1|A0A8V0YKR3_CHICK Computationally mapped isoform of Protein FAM13B OS=Gallus gallus OX=9031 GN=FAM13B PE=3 SV=1 CANONICAL=A0A8V0YKQ9-1" }, "locus": { "chromosome": "13", "start_pos": 14006055, "end_pos": 13976022, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010037026.1", "url": "https://www.ensembl.org/id/ENSGALT00010037026.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021535.1", "url": "https://www.ensembl.org/id/ENSGALP00010021535.1" } ] } }, { "isoform_ac": "A0A8V0YS45-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKQ9/entry#A0A8V0YS45-1", "sequence": { "sequence": "MRKSSSPSLSNCNSVLANKIFGIPLDELQQEGQPDNEVPFIVRHVVDYIEEHGGLEQEGLFQVNGNAETVEWLRQRYDNGEDVDLVKEADVPSAISLLRFFLQELPEPVIPGSLHIHLMQLSQDYNNEDEFGRKLRFLLQQLPPVNYSLLKFLCKFLANVASHHEEIWSASSLAAVFGPDVFHIYTDVEDLKEQEIVSRIMAGLLENYYEFFENEEEDFSSTNDLSSITEQPTAHFALFQMKHFYMKCSFGIAKIIRMACKVLLHSAHISPISILPASADILERTIRAAVEQHLFDLQSSLDNDLKQIQQHRLGCNNDANNPSGDEEGSNNQNDVIENNDIGSSENVEDCSEVSVSTDLGNEDMKHDTVTEEEESVQVLALPSAEPADGLLKQCDKDADVDGENNSERQNSILVDGNDRISSEMFLDSSTKACDLNANTDSEVSGDGDVFVPEEALSVQVPRLDLKNASDGDKWEDPFPAFKSWQEDSESGEAQLSPQAGRMTNHPLEEDCHPILSHRSLDFGQSQRFLHDPETLDSSSKALSFVRTRRASFSSKDDKREDKTPYQLVKKLQKKIKQFEEQFEKERNSKPSYSDIAANPKVLKWMTDLTKLRKQIKDAKQKSSDGEFIPQTRPRSNTLPKSFGSSLDQEDEENGDEMRIVQKEKKPTKEATLELILKRLKEKRVERCLPEDIKKMTKDHLVEEKTSLQKSLLFYESQHGRPVTREERHIVKPLYDRYRLVKQMLTRASITPILGSPSTKRRGQMLQPIIEGETAHFFEEIKEEEEESDGLSADLNDILKSAVQTQSVLSPVENSESDVEDGQEKLTRDLRLSSTRAASMPELLEQLWKARAEKKKLRKTLREFEEEFYQQNGRNVQKEDRVPMLDEYREYKKIKAKLRLLEVLISKQDSSKSI", "length": 913, "header": "tr|A0A8V0YS45-1|A0A8V0YS45_CHICK Computationally mapped isoform of Protein FAM13B OS=Gallus gallus OX=9031 GN=FAM13B PE=3 SV=1 CANONICAL=A0A8V0YKQ9-1" }, "locus": { "chromosome": "13", "start_pos": 14006055, "end_pos": 13976022, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010037032.1", "url": "https://www.ensembl.org/id/ENSGALT00010037032.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021537.1", "url": "https://www.ensembl.org/id/ENSGALP00010021537.1" } ] } }, { "isoform_ac": "A0A8V0YYV8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKQ9/entry#A0A8V0YYV8-1", "sequence": { "sequence": "MRKSSSPSLSNCNSVLANKIFGIPLDELQQEGQPDNEVPFIVRHVVDYIEEHGGLEQEGLFQVNGNAETVEWLRQRYDNGEDVDLVKEADVPSAISLLRFFLQELPEPVIPGSLHIHLMQLSQDYNNEDEFGRKLRFLLQQLPPVNYSLLKFLCKFLANVASHHEEIWSASSLAAVFGPDVFHIYTDVEDLKEQEIVSRIMAGLLENYYEFFENEEEDFSSTNDLSSITEQINDLLEEEEDIKLEQSEELPEDGTEKPIERPAVVHLDVTGSISDSRSVTASTSAHISPISILPASADILERTIRAAVEQHLFDLQSSLDNDLKQIQQHRLGCNNDANNPSGDEEGSNNQNDVIENNDIGSSENVEDCSEVSVSTDLGNEDMKHDTVTEEEESVQVLALPSAEPADGLLKQCDKDADVDGENNSERQNSILVDGNDRISSEMFLDSSTKACDLNANTDSEVSGDGDVFVPEEALSVQVPRLDLKNASDGDKWEAPCPITFPLIDFKTMHLQREGEDPFPAFKSWQEDSESGEAQLSPQAGRMTNHPLEEDCHPILSHRSLDFGQSQRFLHDPETLDSSSKALSFVRTRRASFSSKDDKREDKTPYQLVKKLQKKIKQFEEQFEKERNSKPSYSDIAANPKVLKWMTDLTKLRKQIKDAKQKSSDGEFIPQTRPRSNTLPKSFGSSLDQEDEENGDEMRIVQKEKKPTKEATLELILKRLKEKRVERCLPEDIKKMTKDHLVEEKTSLQKSLLFYESQHGRPGSPSTKRRGQMLQPIIEGETAHFFEEIKEEEEESDGLSADLNDILKSAVQTQSVLSPVENSESDVEDGQEKLTRDLRLSSTRAASMPELLEQLWKARAEKKKLRKTLREFEEEFYQQNGRNVQKEDRVPMLDEYREYKKIKAKLRLLEVLISKQDSSKSI", "length": 921, "header": "tr|A0A8V0YYV8-1|A0A8V0YYV8_CHICK Computationally mapped isoform of Protein FAM13B OS=Gallus gallus OX=9031 GN=FAM13B PE=3 SV=1 CANONICAL=A0A8V0YKQ9-1" }, "locus": { "chromosome": "13", "start_pos": 14006055, "end_pos": 13976022, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010037028.1", "url": "https://www.ensembl.org/id/ENSGALT00010037028.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021536.1", "url": "https://www.ensembl.org/id/ENSGALP00010021536.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-9013148", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013148", "resource": "Reactome", "description": "CDC42 GTPase cycle" }, { "id": "R-GGA-9013149", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013149", "resource": "Reactome", "description": "RAC1 GTPase cycle" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKQ9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKQ9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKQ9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKQ9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 146, "end_pos": 148, "annotation": "n_glycosylation_sequon" }, { "start_pos": 422, "end_pos": 424, "annotation": "n_glycosylation_sequon" }, { "start_pos": 485, "end_pos": 487, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YKQ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKQ9" }, { "id": "PS50238", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50238" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Rho-GAP", "eco_id": "ECO_0000259", "start_pos": 23, "end_pos": 212, "start_aa": "Ile", "end_aa": "Phe", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 146, "end_pos": 148 }, { "start_pos": 422, "end_pos": 424 }, { "start_pos": 485, "end_pos": 487 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YKR6-1", "uniprot_ac": "A0A8V0YKR6", "uniprot_id": "A0A8V0YKR6_CHICK", "mass": { "chemical_mass": 84506.0, "monoisotopic_mass": 84506.0 }, "refseq": { "ac": "XP_015153246", "name": "exostosin-like 1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015153246" }, "gene_names": [ { "name": "EXTL1", "type": "recommended", "evidence": [ { "id": "A0A8V0YKR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKR6" } ] }, { "name": "EXTL1", "type": "synonym", "evidence": [ { "id": "XP_015153246", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015153246" } ] } ], "protein_names": [ { "name": "Exostosin-like 1", "type": "recommended", "evidence": [ { "id": "A0A8V0YKR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKR6/entry#names_and_taxonomy" } ] }, { "name": "2.4.1.224", "type": "synonym", "evidence": [ { "id": "A0A8V0YKR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKR6/entry#names_and_taxonomy" } ] }, { "name": "Exostosin-L", "type": "synonym", "evidence": [ { "id": "A0A8V0YKR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKR6/entry#names_and_taxonomy" } ] }, { "name": "Glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase", "type": "synonym", "evidence": [ { "id": "A0A8V0YKR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKR6/entry#names_and_taxonomy" } ] }, { "name": "Multiple exostosis-like protein", "type": "synonym", "evidence": [ { "id": "A0A8V0YKR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKR6/entry#names_and_taxonomy" } ] }, { "name": "exostosin-like 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015153246", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015153246" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052554.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015153246.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015153246", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015153246" } ] }, { "annotation": "Glycosyltransferase required for the biosynthesis of heparan-sulfate (HS). Transfers N-acetyl-alpha-D-glucosamine to the nascent HS chain (GlcNAcT-II activity). Appears to lack GlcNAcT I and GlcAT-II activities.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKR6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKR6#function" }, { "database": "UniProtKB", "id": "ARBA00057834", "url": "https://www.uniprot.org/uniprotkb/ARBA00057834#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKR6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKR6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "EXTL1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKR6", "locus": {} } ], "crossref": [ { "id": "A0A8V0YKR6", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YKR6", "database": "AlphaFoldDB", "categories": [] }, { "id": "100859367", "url": "https://www.ncbi.nlm.nih.gov/gene/100859367", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004263", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004263", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015338", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015338", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029044", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029044", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040911", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040911", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:100859367", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100859367", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QWNGGKN", "url": "https://omabrowser.org/oma/group/QWNGGKN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YKR6", "url": "https://www.orthodb.org/?gene=A0A8V0YKR6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48261", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48261", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR48261:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48261:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03016", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03016", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF09258", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09258", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015153246", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015153246", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "16213", "url": "https://www.rhea-db.org/rhea/16213", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YKR6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKR6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YKR6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKR6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQTRKKYLFLTFLASWLLLFFFGREQLRRFTFFPRRNVAVRRSWPRWADRTLLHSFAEPWELQGSTDTAQPSPRARRVAQLSTSQGSRCRMESCFDASRCQNGFKVFTYPREHGEPMSESYSKILSSIERSRYYTPRPEEACLFVLSIDTLDRDPLSAHYVRGVEQRIRSFPLWNSGRNHLIFNLYAGTWPNYTEELGFDIGHAMLAKASFHSKNFRPGFDVSIPLFPREHPQRGGQRGWLHHNSVPPKKKYLLVFKGKRYLTGIGSGTRNALHHIHNGQDIVSLTTCRHGKDWERHKDTRCDQDNVDYEKFDYQELLHNSTFCIVPRGRRLGSFRFLEALQAACIPVLLSDGWELPFSEAIDWGKAAVVGSERLLLQIPSAVRCIRPERVLAFQQQTQFLWDAYFSSVDKIVHTTLEIIRDRLLPHRSRSHFLWNTLPGGLLALPDFSTHLGDFPFYYLQHGSGPSDKFTALLRAAPPLGSLSQPTLRLIQAVSRSQYCAQILVLWSCEKPPPPSGTWPQTAVPLTIIQGRTKLSDRFFPYAAIGTDAVLSLDEHSSLSTSEVDFAFVVWRSFPERIVGFSAWSHFWDPEQKRWGYTSRWTNKLSIVLTTAAFYHRYYHSLFTEYLPTGLQELVDSLAACEDILMNLLVAAVTKLPPIKVTQWKQHKEAASQPVKGTAAGSSRRFSQQQDCLNQLVDWFGSMPLVSSQLRLDPVLFKDQVSVLRKKYRYLEKP", "length": 734, "header": "tr|A0A8V0YKR6-1|A0A8V0YKR6_CHICK Isoform 1 of Exostosin-like 1 OS=Gallus gallus OX=9031 GN=EXTL1 PE=3 SV=1 CANONICAL=A0A8V0YKR6-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YKR6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKR6/entry#A0A8V0YKR6-1", "sequence": { "sequence": "MQTRKKYLFLTFLASWLLLFFFGREQLRRFTFFPRRNVAVRRSWPRWADRTLLHSFAEPWELQGSTDTAQPSPRARRVAQLSTSQGSRCRMESCFDASRCQNGFKVFTYPREHGEPMSESYSKILSSIERSRYYTPRPEEACLFVLSIDTLDRDPLSAHYVRGVEQRIRSFPLWNSGRNHLIFNLYAGTWPNYTEELGFDIGHAMLAKASFHSKNFRPGFDVSIPLFPREHPQRGGQRGWLHHNSVPPKKKYLLVFKGKRYLTGIGSGTRNALHHIHNGQDIVSLTTCRHGKDWERHKDTRCDQDNVDYEKFDYQELLHNSTFCIVPRGRRLGSFRFLEALQAACIPVLLSDGWELPFSEAIDWGKAAVVGSERLLLQIPSAVRCIRPERVLAFQQQTQFLWDAYFSSVDKIVHTTLEIIRDRLLPHRSRSHFLWNTLPGGLLALPDFSTHLGDFPFYYLQHGSGPSDKFTALLRAAPPLGSLSQPTLRLIQAVSRSQYCAQILVLWSCEKPPPPSGTWPQTAVPLTIIQGRTKLSDRFFPYAAIGTDAVLSLDEHSSLSTSEVDFAFVVWRSFPERIVGFSAWSHFWDPEQKRWGYTSRWTNKLSIVLTTAAFYHRYYHSLFTEYLPTGLQELVDSLAACEDILMNLLVAAVTKLPPIKVTQWKQHKEAASQPVKGTAAGSSRRFSQQQDCLNQLVDWFGSMPLVSSQLRLDPVLFKDQVSVLRKKYRYLEKP", "length": 734, "header": "tr|A0A8V0YKR6-1|A0A8V0YKR6_CHICK Isoform 1 of Exostosin-like 1 OS=Gallus gallus OX=9031 GN=EXTL1 PE=3 SV=1 CANONICAL=A0A8V0YKR6-1" }, "locus": { "chromosome": "23", "start_pos": 3592522, "end_pos": 3587277, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032411.1", "url": "https://www.ensembl.org/id/ENSGALT00010032411.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019176.1", "url": "https://www.ensembl.org/id/ENSGALP00010019176.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 135, "start_aa": "Thr", "end_pos": 135, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr135", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:100859367", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100859367", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZLU1-1", "protein_name": "Exostosin-like 1", "gene_name": "Extl1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLWRRKSFWLALSAFWLLLILLGVFPLRLAVSPRPLPGRSQGWPRWLDATFLQSFSQPETNPEEDVQQLPRVSRGSSCTWGACFDTSKCRGKVLKIFVHSAAGPTTEAQRRILDSLEGSRYYALSPAEACLLLFLPSQDRRGACGPLPPNWNGGRNHLVLSLYPAPCTRLGQAMVAEASPSLDIFRPGFDVALPYLPEAHPLKGGAPGSLQRHGPQPGATLVAVAEERGRWRITTTHASACPWDRNCEQDPGPQQTYPGEILPNVTFCLIPGHRSATSCFLQALQAGCIPVLLSPRWELPFSEVIDWTKAAIVADERLPLQVLAALREMLPSRVLALRQQTQFLWTAYFSSVEKVVHTTLEIIQDRIWGASAHPSLMWNSPPGALLALPTFSTSLQDFPFYHLQLGSSPGSSFSAVIWVGVSEESPPKLIQEVAGSRHCAQILILWNSEKPPPDRWPKTAVPLTVIEGHRKVSDRFFLYSNISTNVILSLDAQSTLSTSEVDFAFVVWQSFPERMVGFVTWSHFWDEARQGWGYSAEMANEFSMVLTTAAFYHRYYHTLFTHSLPKALRSIADETPTCVDILMNFLVATVTKLPPIKVPYSRQHQEAAPMASEGPRPVPEPQALDQDCINRLAAGLGHMPLVSSRVRLDPVLFKDPVSVQRKKYRSLEKP", "length": 670 }, "evidence": [ { "id": "A0A8V0YKR6", "url": "https://omabrowser.org/oma/group/A0A8V0YKR6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q92935-1", "protein_name": "Exostosin-like 1", "gene_name": "EXTL1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MQSWRRRKSLWLALSASWLLLVLLGGFSLLRLALPPRPRPGASQGWPRWLDAELLQSFSQPGELPEDAVSPPQAPHGGSCNWESCFDTSKCRGDGLKVFVYPAVGTISETHRRILASIEGSRFYTFSPAGACLLLLLSLDAQTGECSSMPLQWNRGRNHLVLRLHPAPCPRTFQLGQAMVAEASPTVDSFRPGFDVALPFLPEAHPLRGGAPGQLRQHSPQPGVALLALEEERGGWRTADTGSSACPWDGRCEQDPGPGQTQRQETLPNATFCLISGHRPEAASRFLQALQAGCIPVLLSPRWELPFSEVIDWTKAAIVADERLPLQVLAALQEMSPARVLALRQQTQFLWDAYFSSVEKVIHTTLEVIQDRIFGTSAHPSLLWNSPPGALLALSTFSTSPQDFPFYYLQQGSRPEGRFSALIWVGPPGQPPLKLIQAVAGSQHCAQILVLWSNERPLPSRWPETAVPLTVIDGHRKVSDRFYPYSTIRTDAILSLDARSSLSTSEVDFAFLVWQSFPERMVGFLTSSHFWDEAHGGWGYTAERTNEFSMVLTTAAFYHRYYHTLFTHSLPKALRTLADEAPTCVDVLMNFIVAAVTKLPPIKVPYGKQRQEAAPLAPGGPGPRPKPPAPAPDCINQIAAAFGHMPLLSSRLRLDPVLFKDPVSVQRKKYRSLEKP", "length": 676 }, "evidence": [ { "id": "A0A8V0YKR6", "url": "https://omabrowser.org/oma/group/A0A8V0YKR6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9JKV7-1", "protein_name": "Exostosin-like 1", "gene_name": "Extl1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLWRRKSFWLALSAFWLLLVLLGVFPLRLAVLPGPLPGRSQGWPRWLDAAFLQSFSQSETNPEDVAQLPRVSRGSSCTWGACFDTSKCRGKVLKIFVHSPAGPTSEAQRRILDSLEGSRYSALSPADACLLLFLPSQDRRGACGPLPPNWNGGRNHLVLSLYPAPCTRLGQAMVAEASPSSDIFRPGFDLALPYLPEAHPLRGGAPGKLQQHSPQPGATLLAVAEEKGRWRITSTHASACLWDRHCEQDPGPQQTYPGETLPNATFCLIPGHRSATSCFLQALQAGCIPVLLSPRWELPFSEVIDWTKAAIIADERLPLQVLAALREMLPSRVLALRQQTQFLWTAYFSSVEKVIHTTLEIIQDRIWGASGHPSLMWNSPPGALLALPTFSTSLQDFPFYHLQLGSGPGSSFSAVIWVGASGESLLKLIQEVAGSRHCAQILILWNSEKLPPDRWPETAVPLTVIKGHRKVSNRFFPYSNISTNVILSLDAQSTLSTSEVDFAFVVWQSFPERMVGFLSGSHFWDEAQGGWGYRTGMTNEFSMVLTTAAFYHRYYHTLFTHSLPKALRTIADETPTCVDVLMNFLVATVTKLPPIKVPYGRQHPEAVPMDSGDPRPVPEPQPLDQDCINRLAAGFGHMPLVSSQVRLDPVLFKDPVSVQRKKYRSLEKP", "length": 669 }, "evidence": [ { "id": "A0A8V0YKR6", "url": "https://omabrowser.org/oma/group/A0A8V0YKR6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKR6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKR6" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKR6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKR6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "acetylglucosaminyltransferase activity", "id": "GO:0008375", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008375", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKR6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKR6" } ], "pmid": "" }, { "name": "glucuronosyltransferase activity", "id": "GO:0015020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKR6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKR6" } ], "pmid": "" }, { "name": "glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity", "id": "GO:0050508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050508", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKR6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKR6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "heparan sulfate proteoglycan biosynthetic process", "id": "GO:0015012", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015012", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKR6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKR6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 192, "end_pos": 194, "annotation": "n_glycosylation_sequon" }, { "start_pos": 320, "end_pos": 322, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "16213", "name": "", "equation": "3-O-{[(1->4)-beta-D-GlcA-(1->4)-alpha-D-GlcNAc](n)-(1->4)-beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl}-L-seryl-[protein] + UDP-N-acetyl-alpha-D-glucosamine = 3-O-{alpha-D-GlcNAc-[(1->4)-beta-D-GlcA-(1->4)-alpha-D-GlcNAc](n)-(1->4)-beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl}-L-seryl-[protein] + UDP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YKR6-1", "A0A8V0ZI75-1" ], "evidence": [ { "id": "16213", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/16213" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A8V0YKR6", "gene_name": "EXTL1", "activity": [ { "ec_number": "2.4.1.224", "activity": "3-O-{[(1->4)-beta-D-GlcA-(1->4)-alpha-D-GlcNAc](n)-(1->4)-beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl}-L-seryl-[protein] + UDP-N-acetyl-alpha-D-glucosamine = 3-O-{alpha-D-GlcNAc-[(1->4)-beta-D-GlcA-(1->4)-alpha-D-GlcNAc](n)-(1->4)-beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl}-L-seryl-[protein] + UDP + H(+).", "evidence": [ { "id": "A0A8V0YKR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKR6" } ] }, { "ec_number": "2.4.1.224", "activity": "", "evidence": [ { "id": "A0A8V0YKR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKR6" } ] } ] }, { "uniprot_ac": "A0A8V0ZI75", "gene_name": "EXT2", "activity": [ { "ec_number": "2.4.1.224", "activity": "3-O-{[(1->4)-beta-D-GlcA-(1->4)-alpha-D-GlcNAc](n)-(1->4)-beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl}-L-seryl-[protein] + UDP-N-acetyl-alpha-D-glucosamine = 3-O-{alpha-D-GlcNAc-[(1->4)-beta-D-GlcA-(1->4)-alpha-D-GlcNAc](n)-(1->4)-beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl}-L-seryl-[protein] + UDP + H(+).", "evidence": [ { "id": "A0A8V0ZI75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI75" } ] }, { "ec_number": "2.4.1.224", "activity": "", "evidence": [ { "id": "A0A8V0ZI75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI75" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YKR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKR6" }, { "id": "PF03016", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03016" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Exostosin GT47", "eco_id": "ECO_0000259", "start_pos": 102, "end_pos": 383, "start_aa": "Asn", "end_aa": "Val", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0YKR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKR6" }, { "id": "PF09258", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09258" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Glycosyl transferase 64", "eco_id": "ECO_0000259", "start_pos": 484, "end_pos": 717, "start_aa": "Ser", "end_aa": "Phe", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.4.1.224", "ec_name": "3-O-{[(1->4)-beta-D-GlcA-(1->4)-alpha-D-GlcNAc](n)-(1->4)-beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl}-L-seryl-[protein] + UDP-N-acetyl-alpha-D-glucosamine = 3-O-{alpha-D-GlcNAc-[(1->4)-beta-D-GlcA-(1->4)-alpha-D-GlcNAc](n)-(1->4)-beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl}-L-seryl-[protein] + UDP + H(+).", "evidence": [ { "id": "2.4.1.224", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.1.224" }, { "id": "2.4.1.224", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.4.1.224" } ] } ], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 135 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 192, "end_pos": 194 }, { "start_pos": 320, "end_pos": 322 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YKU0-1", "uniprot_ac": "A0A8V0YKU0", "uniprot_id": "A0A8V0YKU0_CHICK", "mass": { "chemical_mass": 17051.0, "monoisotopic_mass": 17051.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "RNase H type-1 domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A8V0YKU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKU0/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKU0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKU0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKU0", "locus": {} } ], "crossref": [ { "id": "IPR012337", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012337", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036397", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036397", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YKU0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKU0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YKU0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKU0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEKKEHCILRGINALNAQIFSTDSIFHQTYSSRADLKEMPMENADWDLFVDSSNFVQDGKWKVGNAVVTVKEMTEAKALLSNTLVQKAKLIALLRVLELSKDRTVYTWTDSEFDSGVFHAHGHICRQKGLLTSQESPVKYGSTTFTSYRSA", "length": 151, "header": "tr|A0A8V0YKU0-1|A0A8V0YKU0_CHICK Isoform 1 of RNase H type-1 domain-containing protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0YKU0-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YKU0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKU0/entry#A0A8V0YKU0-1", "sequence": { "sequence": "MEKKEHCILRGINALNAQIFSTDSIFHQTYSSRADLKEMPMENADWDLFVDSSNFVQDGKWKVGNAVVTVKEMTEAKALLSNTLVQKAKLIALLRVLELSKDRTVYTWTDSEFDSGVFHAHGHICRQKGLLTSQESPVKYGSTTFTSYRSA", "length": 151, "header": "tr|A0A8V0YKU0-1|A0A8V0YKU0_CHICK Isoform 1 of RNase H type-1 domain-containing protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0YKU0-1" }, "locus": { "chromosome": "Z", "start_pos": 54269606, "end_pos": 54269472, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032788.1", "url": "https://www.ensembl.org/id/ENSGALT00010032788.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019420.1", "url": "https://www.ensembl.org/id/ENSGALP00010019420.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "nucleic acid binding", "id": "GO:0003676", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003676", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKU0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKU0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YKU7-1", "uniprot_ac": "A0A8V0YKU7", "uniprot_id": "A0A8V0YKU7_CHICK", "mass": { "chemical_mass": 30059.0, "monoisotopic_mass": 30059.0 }, "refseq": {}, "gene_names": [ { "name": "UPRT", "type": "recommended", "evidence": [ { "id": "A0A8V0YKU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKU7" } ] } ], "protein_names": [ { "name": "Uracil phosphoribosyltransferase homolog", "type": "recommended", "evidence": [ { "id": "A0A8V0YKU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKU7/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKU7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKU7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "UPRT", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKU7", "locus": { "chromosome": "4", "start_pos": 12529025, "end_pos": 12517016, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013488", "url": "https://www.ensembl.org/id/ENSGALG00010013488" } ] } } ], "crossref": [ { "id": "A0A8V0YKU7", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YKU7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000007793", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000007793", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd06223", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06223", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "422327", "url": "https://www.ncbi.nlm.nih.gov/gene/422327", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000836", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000836", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029057", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029057", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:422327", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422327", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "NLFCTPM", "url": "https://omabrowser.org/oma/group/NLFCTPM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YKU7", "url": "https://www.orthodb.org/?gene=A0A8V0YKU7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NP42", "url": "https://www.orthodb.org/?gene=F1NP42", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PF14681", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14681", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YKU7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKU7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YKU7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKU7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NP42", "url": "https://www.uniprot.org/uniprotkb/F1NP42", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NP42-1", "url": "https://www.uniprot.org/uniprotkb/F1NP42-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "AWRPRSARGEGAPAHGGDAVPQPAARRGRRPAAPGRADGAGGRLLPADPLRRALRGQQQRQPQPGQQQRQQRGGGGPQPRGGGLRVAARSAAEAAAHERSDPGAADHHQGQIRLVVEEGLNQLPYTECTVTTPTGYKYEGVKFEKGNCGVSIMRSGEAMEQGLRDCCRSIRIGKILIQSDEETQRAKVYYAKFPPDIYRRKVLLMYPILSTGNTVIEAVKVLIEHGVQPSVIILLSLFSTPHGAKSIIQEFPEITILTTEVHPVAPTHFGQKYFGTD", "length": 277, "header": "tr|A0A8V0YKU7-1|A0A8V0YKU7_CHICK Isoform 1 of Uracil phosphoribosyltransferase homolog OS=Gallus gallus OX=9031 GN=UPRT PE=3 SV=1 CANONICAL=A0A8V0YKU7-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YKU7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKU7/entry#A0A8V0YKU7-1", "sequence": { "sequence": "AWRPRSARGEGAPAHGGDAVPQPAARRGRRPAAPGRADGAGGRLLPADPLRRALRGQQQRQPQPGQQQRQQRGGGGPQPRGGGLRVAARSAAEAAAHERSDPGAADHHQGQIRLVVEEGLNQLPYTECTVTTPTGYKYEGVKFEKGNCGVSIMRSGEAMEQGLRDCCRSIRIGKILIQSDEETQRAKVYYAKFPPDIYRRKVLLMYPILSTGNTVIEAVKVLIEHGVQPSVIILLSLFSTPHGAKSIIQEFPEITILTTEVHPVAPTHFGQKYFGTD", "length": 277, "header": "tr|A0A8V0YKU7-1|A0A8V0YKU7_CHICK Isoform 1 of Uracil phosphoribosyltransferase homolog OS=Gallus gallus OX=9031 GN=UPRT PE=3 SV=1 CANONICAL=A0A8V0YKU7-1" }, "locus": { "chromosome": "4", "start_pos": 12528669, "end_pos": 12517018, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032455.1", "url": "https://www.ensembl.org/id/ENSGALT00010032455.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019206.1", "url": "https://www.ensembl.org/id/ENSGALP00010019206.1" } ] } }, { "isoform_ac": "F1NP42-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKU7/entry#F1NP42-1", "sequence": { "sequence": "MEAMPCHNQRLGAAGGPRPQDEQTAPAGGCSRLIRFAEPSEGSSSGSPSPDSSSGSNGAAAAPSPAAEDCASPLGAQLKLLPMNDQIRELQTIIRDKTASRGDFVFSADRLIRLVVEEGLNQLPYTECTVTTPTGYKYEGVKFEKGNCGVSIMRSGEAMEQGLRDCCRSIRIGKILIQSDEETQRAKVYYAKFPPDIYRRKVLLMYPILSTGNTVIEAVKVLIEHGVQPSVIILLSLFSTPHGAKSIIQEFPEITILTTEVHPVAPTHFGQKYFGTD", "length": 277, "header": "tr|F1NP42-1|F1NP42_CHICK Computationally mapped isoform of Uracil phosphoribosyltransferase homolog OS=Gallus gallus OX=9031 GN=UPRT PE=3 SV=3 CANONICAL=A0A8V0YKU7-1" }, "locus": { "chromosome": "4", "start_pos": 12528669, "end_pos": 12517061, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032469.1", "url": "https://www.ensembl.org/id/ENSGALT00010032469.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019217.1", "url": "https://www.ensembl.org/id/ENSGALP00010019217.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:422327", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422327", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6G3Q5-1", "protein_name": "Uracil phosphoribosyltransferase homolog", "gene_name": "Uprt", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MATELQRPDSMPCHNRQVNSTSSPSPERLLAEDPVLDHAEENNAAMAKLTLLPGHAHSSVLSERDSPACCSTNLHCENHSDSSDSGNYEAPVGDSLLGDCELYPQIGAQLKLLPMNDQIRELQTIIRDKTASRGDFMFSADRLIRLVVEEGLNQLPYKECMVTTPTGHKYEGVKFEKGNCGVSIMRSGEAMEQGLRDCCRSIRIGKILIQSDEETQRAKVYYAKFPPDIHRRKVLLMYPILSTGNTVIEAVKVLIEHGVQPSVIILLSLFSTPHGAKSIIQEFPEITILTTEVHPVAPTHFGQKYFGTD", "length": 309 }, "evidence": [ { "id": "A0A8V0YKU7", "url": "https://omabrowser.org/oma/group/A0A8V0YKU7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "B1AVZ0-1", "protein_name": "Uracil phosphoribosyltransferase homolog", "gene_name": "Uprt", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASELQRPDSMPCHNRQVNSTSSPSPEHLLAEDRVLDHAEENNAAMAKLTLLPGHAHSSVLSERDSPACCSTNLHSENHSDSSDSGNYDAPVGGDSLLGDCELSRQIGAQLKLLPMNDQIRELQTIIRDKTASRGDFMFSADRLIRLVVEEGLNQLPYKECMVTTPTGHKYEGVKFEKGNCGVSIMRSGEAMEQGLRDCCRSIRIGKILIQSDEETQRAKVYYAKFPPDIHRRKVLLMYPILSTGNTVIEAVKVLIEHGVQPSVIILLSLFSTPHGAKSIIQEFPEITILTTEVHPVAPTHFGQKYFGTD", "length": 310 }, "evidence": [ { "id": "A0A8V0YKU7", "url": "https://omabrowser.org/oma/group/A0A8V0YKU7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F1N6Q4-1", "protein_name": "Uracil phosphoribosyltransferase homolog", "gene_name": "UPRT", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MATELRCPDSMPCHNQQVNSASTQNPEPQQAGDLILAHAGGNSDSAATLTLLSGHAHSSVPAELDPQASGGATFNSENNGGTGNYDAPASDSLLGDCEISRQIGAQLKLLPMNDQIRELQTIIRDKTASRGDFMFSADRLIRLVVEEGLNQLPYEECMVTTPTGYKYEGVKFEKGNCGVSIMRSGEAMEQGLRDCCRSIRIGKILIQSDEETQRAKVYYAKFPPDIYRRKVLLMYPILSTGNTVIEAVKVLIEHGVQPSVIILLSLFSTPHGAKSIIQEFPEITILTTEVHPVAPTHFGQKYFGTD", "length": 306 }, "evidence": [ { "id": "A0A8V0YKU7", "url": "https://omabrowser.org/oma/group/A0A8V0YKU7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1RPJ7-1", "protein_name": "Uracil phosphoribosyltransferase homolog", "gene_name": "UPRT", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MATELRCPDSMPCHNQQVNSASTPSLEPQQPGDLMPDHAGANSDSTAKQTLLSVHAHSIVTAERDPKACGSASFNSESNGGNYDASASDSLLGDCELFRQIGAQLKLLPMNDQIRELQTIIRDKTASRGDFMFSADRLIRLVVEEGLNQLPYKECMVTTPTGYKYEGVKFEKGNCGVSIMRSGEAMEQGLRDCCRSIRIGKILIQSDEETQRAKVYYAKFPPDIYRRKVLLMYPILSTGNTVIEAVKVLIEHGVQPSVIILLSLFSTPHGAKSIIQEFPEITILTTEVHPVAPTHFGQKYFGTD", "length": 304 }, "evidence": [ { "id": "A0A8V0YKU7", "url": "https://omabrowser.org/oma/group/A0A8V0YKU7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "M9PHI7-1", "protein_name": "Uracil phosphoribosyltransferase homolog", "gene_name": "kri", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MRTGSPSSSGSQSEEGSSSSDHQQPQQEAQEQEQQLHTPTHAHAAVPAATSEEILAEYGSNLKLLECNSQVAELLTILRDKNTTRSDFKFYADRLIRLVIEESLNQLPYTHCDVETPTGAIYEGLKYRSGNCGVSIIRSGEAMEQGLRDCCRSIRIGKILVESDANTHEARVVYARFPDDIGSRQVLLMYPIMSTGNTVLQAVNVLREHGVPESCIILSNLFCTPIAARTVVNAFPKLKILTSELHPVAPNHFGQKYFDCI", "length": 261 }, "evidence": [ { "id": "A0A8V0YKU7", "url": "https://omabrowser.org/oma/group/A0A8V0YKU7/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q96BW1-1", "protein_name": "Uracil phosphoribosyltransferase homolog", "gene_name": "UPRT", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MATELQCPDSMPCHNQQVNSASTPSPEQLRPGDLILDHAGGNRASRAKVILLTGYAHSSLPAELDSGACGGSSLNSEGNSGSGDSSSYDAPAGNSFLEDCELSRQIGAQLKLLPMNDQIRELQTIIRDKTASRGDFMFSADRLIRLVVEEGLNQLPYKECMVTTPTGYKYEGVKFEKGNCGVSIMRSGEAMEQGLRDCCRSIRIGKILIQSDEETQRAKVYYAKFPPDIYRRKVLLMYPILSTGNTVIEAVKVLIEHGVQPSVIILLSLFSTPHGAKSIIQEFPEITILTTEVHPVAPTHFGQKYFGTD", "length": 309 }, "evidence": [ { "id": "A0A8V0YKU7", "url": "https://omabrowser.org/oma/group/A0A8V0YKU7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKU7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKU7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKU7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKU7" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKU7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKU7" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKU7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKU7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YKU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKU7" }, { "id": "PF14681", "database": "Pfam", "url": 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43274.0, "monoisotopic_mass": 43274.0 }, "refseq": { "ac": "XP_004934562", "name": "dnaJ homolog subfamily C member 28", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004934562" }, "gene_names": [ { "name": "DNAJC28", "type": "recommended", "evidence": [ { "id": "A0A8V0YKV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKV1" } ] }, { "name": "DNAJC28", "type": "synonym", "evidence": [ { "id": "XP_004934562", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004934562" } ] } ], "protein_names": [ { "name": "DnaJ heat shock protein family (Hsp40) member C28", "type": "synonym", "evidence": [ { "id": "A0A8V0YKV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKV1/entry#names_and_taxonomy" } ] }, { "name": "dnaJ homolog subfamily C member 28", "type": "synonym", "evidence": [ { "id": "XP_004934562", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004934562" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_004934562.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004934562", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004934562" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKV1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKV1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "DNAJC28", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKV1", "locus": { "chromosome": "1", "start_pos": 105417583, "end_pos": 105421491, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012070", "url": "https://www.ensembl.org/id/ENSGALG00010012070" } ] } } ], "crossref": [ { "id": "cd06257", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06257", "database": "CDD", "categories": [ "Protein 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"categories": [ "Protein Classification" ] }, { "id": "A0A8V0YKV1", "url": "https://www.orthodb.org/?gene=A0A8V0YKV1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR39158", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR39158", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR39158:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR39158:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00226", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00226", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF09350", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09350", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_004934562", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004934562", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YKV1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKV1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YKV1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKV1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLTNTIGHHLMVHQAMIPRSLKPFSYICGKRMLSGYKPKRNVKDSYKILELEEGCSLDDIRNSYRSLAKKYHPDSGSITADSAAFVKVEEAYRVVLDDVANKKKPSENKEEEEEDQLKSNAPQHRHYLSFEGVGYGTPSQREKQYMQFRVDRATEQVLAYRTRKLESQYVATDLMRAKDVRQSKKVKITQAVERLVEDLIQESMAKGDFDNLSGKGKPLQKFSDCPHIDPMTHNLNRILIDNGYQPEWILLQKEIRETIERLRKSLVVSRSKLGEPMAPHRLKEWNHICQQFVEDIRKLNKRIDSFNLVVPILSRQMVHFSADKEIIRAQKTYEALMENTEASGSHTKEDKGEGVKRFGWKSSLLKWFNTTLK", "length": 373, "header": "tr|A0A8V0YKV1-1|A0A8V0YKV1_CHICK Isoform 1 of DnaJ heat shock protein family (Hsp40) member C28 OS=Gallus gallus OX=9031 GN=DNAJC28 PE=4 SV=1 CANONICAL=A0A8V0YKV1-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YKV1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKV1/entry#A0A8V0YKV1-1", "sequence": { "sequence": "MLTNTIGHHLMVHQAMIPRSLKPFSYICGKRMLSGYKPKRNVKDSYKILELEEGCSLDDIRNSYRSLAKKYHPDSGSITADSAAFVKVEEAYRVVLDDVANKKKPSENKEEEEEDQLKSNAPQHRHYLSFEGVGYGTPSQREKQYMQFRVDRATEQVLAYRTRKLESQYVATDLMRAKDVRQSKKVKITQAVERLVEDLIQESMAKGDFDNLSGKGKPLQKFSDCPHIDPMTHNLNRILIDNGYQPEWILLQKEIRETIERLRKSLVVSRSKLGEPMAPHRLKEWNHICQQFVEDIRKLNKRIDSFNLVVPILSRQMVHFSADKEIIRAQKTYEALMENTEASGSHTKEDKGEGVKRFGWKSSLLKWFNTTLK", "length": 373, "header": "tr|A0A8V0YKV1-1|A0A8V0YKV1_CHICK Isoform 1 of DnaJ heat shock protein family (Hsp40) member C28 OS=Gallus gallus OX=9031 GN=DNAJC28 PE=4 SV=1 CANONICAL=A0A8V0YKV1-1" }, "locus": { "chromosome": "1", "start_pos": 105420001, "end_pos": 105418883, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028916.1", "url": "https://www.ensembl.org/id/ENSGALT00010028916.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016674.1", "url": "https://www.ensembl.org/id/ENSGALP00010016674.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:770607", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:770607", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A9J7FYK6-1", "protein_name": "DnaJ homolog subfamily C member 28", "gene_name": "Dnajc28", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MNMMCTKMAQTLRPRLISASLTPRGVTLLSGPGSRMISTHKPKKKIKEYYSLLNLREGCSVDDVRESFHKLAKVYHPDSGSNDANSATFIKIEEAYRNVLSHVIKQTQARQKAEDTEEEDKFKYNTPQHRHYLSFEGVGFGTPSQREKQYRQFRADRATEQVMEYQRQKLERELFANSITVKDVRQSKELKITQAMERLVEDLIQESMAKGDFDNLSGKGKPLKKFSGCSYIDPMTHNLNRILIDNGYQPEWILMQKEIKDTIEQLREALLVSRKKLGNPLTPGGQKQWNQVCEKFQENIRKLNKRISDFNLIVPILTRQKVHFDAQKEVIRVQKMYEAFIEAKEITEENPTDISKEEEKTPRVKTGFLNWLNLWKFIKI", "length": 380 }, "evidence": [ { "id": "A0A8V0YKV1", "url": "https://omabrowser.org/oma/group/A0A8V0YKV1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "F1MFP4-1", "protein_name": "DnaJ heat shock protein family (Hsp40) member C28", "gene_name": "DNAJC28", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MMAQILRPHLRSASVIPNRMKMGPYLVVIRTRMMSTHKSKRNIREYYGLLNLDEGCSADDVRESFRKLAKQYHPDGGSSTADSATFIRIEEAYRKVLSHVIEQTNARQSKVEDTEEEEEKFKYKTPQHRHYLSFEGIGFGTPSQREKQYRQFRADRATEQVMEYQKQKLQSQYFTDSVTVKDVRHSKERKITRAIERLVEDLIQESMAKGDFDNLSGKGKPLKKFSGCSYIDPMTHNLNRILIDNGYQPEWILMQKEIKDTIDQLREAILASRKKLGNPMTSAEQKQWNQVCEQFQEDIKKLNKRINDFNLIVPLLTRQKVHFDAQKEIARTQEIYTTLIKIKEITNKNPNNTDPGEGEKTPGVKTVFFNWMNVWKFIKI", "length": 380 }, "evidence": [ { "id": "A0A8V0YKV1", "url": "https://omabrowser.org/oma/group/A0A8V0YKV1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q6AYG2-1", "protein_name": "DnaJ heat shock protein family (Hsp40) member C28", "gene_name": "Dnajc28", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVNTVCAKMARILRLHLTNASLIPPGVKLLSDPGSRMISTHKPKELSEYYRLLNLNEGCSADNIREAFHRLAKQYHPDSGSADADSATFIKIEEAYRNVLSHVIKQMQARQNKAEDAEEEAEKFKYNTPQHRHYLSFEGVGFGTPSQREKQYRQFRADRATEQVMEYQRQKLQREYFANSITVKDVWQSKQQKITQAMDRLVEDLIQESMAKGDFDNLSGKGKPLKKFSGCSYIDPMTHNLNRILIDNGYQPEWILMQKEIKDTIEQLREGLLVSRKKLGSPLSPVGQKQWTHVCEQFQEDIRKLNKRISDFNLIVPILTRQKVHFDAQKEITRVQEIYRAFIEAKEVAEDKQTDISQGEEEKTPSIKAGFLNWLNLWKFIKI", "length": 383 }, "evidence": [ { "id": "A0A8V0YKV1", "url": "https://omabrowser.org/oma/group/A0A8V0YKV1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8VCE1-1", "protein_name": "DnaJ homolog subfamily C member 28", "gene_name": "Dnajc28", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MINTVCMKTTRILRLHLTNASLIPPGIKMLSDPRSRMISTHESQKLREYYRLLNLDEGCSVDDVRESFHKLARQYHPDSGSSDADSATFIKIEEAYRNVLSHAIKRMHAGQDKAEDAAEDEEEGKFKYNTPQHRHYLSFEGVGFGTPSQREKQYRQFRADRATEQVMEYQRQKLQREFFANSITVKDVRQSKQQKITQAIERLVEDLIQESMAKGDFDNLSGKGKPLKKFSGCSYIDPMTHNLNRILIDNGYQPEWILMQKEIKDTIEQLREALLMSRKKLGNPLSPTEQKQWAQVCEQFQEKIRKLNKRINDFNLIVPILTRQKVHFDAQKEIIRVQEMYGAFVEANEVTEENQTDVSQGEESKTPRVKAGFLNWLNLWKSIKI", "length": 385 }, "evidence": [ { "id": "A0A8V0YKV1", "url": "https://omabrowser.org/oma/group/A0A8V0YKV1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9NX36-1", "protein_name": "DnaJ homolog subfamily C member 28", "gene_name": "DNAJC28", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNTMYVMMAQILRSHLIKATVIPNRVKMLPYFGIIRNRMMSTHKSKKKIREYYRLLNVEEGCSADEVRESFHKLAKQYHPDSGSNTADSATFIRIEKAYRKVLSHVIEQTNASQSKGEEEEDVEKFKYKTPQHRHYLSFEGIGFGTPTQREKHYRQFRADRAAEQVMEYQKQKLQSQYFPDSVIVKNIRQSKQQKITQAIERLVEDLIQESMAKGDFDNLSGKGKPLKKFSDCSYIDPMTHNLNRILIDNGYQPEWILKQKEISDTIEQLREAILVSRKKLGNPMTPTEKKQWNHVCEQFQENIRKLNKRINDFNLIVPILTRQKVHFDAQKEIVRAQKIYETLIKTKEVTDRNPNNLDQGEGEKTPEIKKGFLNWMNLWKFIKIRSF", "length": 388 }, "evidence": [ { "id": "A0A8V0YKV1", "url": "https://omabrowser.org/oma/group/A0A8V0YKV1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VM54-1", "protein_name": "J domain-containing protein", "gene_name": "Dmel\\CG43322", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MWLAGNLFKGSVAIRFGRLLHLKRKEVYMECFRILGVHESADQNTVRHAYLDLVKRVHPDSGTEEASAERFQQVDEAFRVLQEKFAKGRRNIQEDEEGAMEFDIKHTAPQHRQYLSNEGIGVGTPFQRQKQYQQVRAMKAQERVLEHRIDKAAAGEKTLMSKGGSHFRKHAIKTKYGIDRVVEDLIQEAMSKGDFNNLNGSGKPLSSAQSQNPYLDFTTHKLNKIMLDNGFTPEWISLGKDIRDAIAQLKTKLRQERKYYGEWPLQRPDDLAAWKIFTLNHQDDVKQLNKLIDKYNLIVPILENQFFRLHLDRMAEPIFKDPELQRNVIRPEMKSKPSSNLENQGSASTSLFSLISKLL", "length": 359 }, "evidence": [ { "id": "A0A8V0YKV1", "url": "https://omabrowser.org/oma/group/A0A8V0YKV1/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 211, "end_pos": 213, "annotation": "n_glycosylation_sequon" }, { "start_pos": 369, "end_pos": 371, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YKV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKV1" }, { "id": "PS50076", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50076" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "J", "eco_id": "ECO_0000259", "start_pos": 44, "end_pos": 118, "start_aa": "Asp", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 211, "end_pos": 213 }, { "start_pos": 369, "end_pos": 371 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YKY3-1", "uniprot_ac": "A0A8V0YKY3", "uniprot_id": "A0A8V0YKY3_CHICK", "mass": { "chemical_mass": 60766.0, "monoisotopic_mass": 60766.0 }, "refseq": { "ac": "XP_040524489", "name": "sodium-dependent glucose transporter 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040524489" }, "gene_names": [ { "name": "MFSD4B", "type": "recommended", "evidence": [ { "id": "A0A8V0YKY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKY3" } ] }, { "name": "MFSD4B", "type": "synonym", "evidence": [ { "id": "XP_040524489", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040524489" } ] } ], "protein_names": [ { "name": "Major facilitator superfamily domain containing 4B", "type": "synonym", "evidence": [ { "id": "A0A8V0YKY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKY3/entry#names_and_taxonomy" } ] }, { "name": "sodium-dependent glucose transporter 1", "type": "synonym", "evidence": [ { "id": "XP_040524489", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040524489" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052575.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040524489", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040524489" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKY3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKY3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MFSD4B", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKY3", "locus": { "chromosome": "3", "start_pos": 65892883, "end_pos": 65900413, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013679", "url": "https://www.ensembl.org/id/ENSGALG00010013679" } ] } } ], "crossref": [ { "id": "A0A8V0YKY3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YKY3", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd17454", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd17454", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "428623", "url": "https://www.ncbi.nlm.nih.gov/gene/428623", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011701", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011701", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036259", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036259", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:428623", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:428623", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "IPWCKKA", "url": "https://omabrowser.org/oma/group/IPWCKKA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YKY3", "url": "https://www.orthodb.org/?gene=A0A8V0YKY3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23121", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23121", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23121:SF9", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23121:SF9", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07690", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07690", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-189200", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-189200", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_040524489", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040524489", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YKY3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKY3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YKY3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKY3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAGAERKKHVRFAGSAQVAAGPGPGPGPGPGPRLPAAPHAEVAVVGGRRCGEGAALRWCVSAALCAAFLGLGTSIAVLGPTFQNLADNVHKNVTDIYYIFVGRSLGYLGGSVLGGILFDHVNAHLLLAFSMLGTTAGLFAIPWCKRSLLLTALMSLIGAAMGVLDTGGNVLALNTWGTEAGPHLQALHFSFAMGAFVAPILAKMAMGNSEPRDLQAGENASQSVLSPVPTASATLALKHHLGVDFLWSYIVIGTYLLFVSFFFFILYSKSSSVRDKSKASAQKCKVAKYHHVLIILLFLFFLCYVGAEVTYGSYIFTYAKVFAEMKESEAAALNSVFWGAFAVCRAVSVFCAACLYPGTMIVLSLIGSAVSSSSLAFFAHYPISLWAGTAVYGASMATIFPSGISWIEQYTVIQGKSASLFVVGAALGEMCIPAVVGYLQGRFHHVPVVMYTALGTSAMTAVLFPVMYKLATASGESSREMSESEDRKALLSSSGLNEDEEDEEDAGEWNEADFEVIEMNDTLRNSVVETSLKAAGDSSSEASLQPHPADAGGDFPVAAGSSPGRKSMNVDREKND", "length": 576, "header": "tr|A0A8V0YKY3-1|A0A8V0YKY3_CHICK Isoform 1 of Major facilitator superfamily domain containing 4B OS=Gallus gallus OX=9031 GN=MFSD4B PE=1 SV=1 CANONICAL=A0A8V0YKY3-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YKY3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKY3/entry#A0A8V0YKY3-1", "sequence": { "sequence": "MAGAERKKHVRFAGSAQVAAGPGPGPGPGPGPRLPAAPHAEVAVVGGRRCGEGAALRWCVSAALCAAFLGLGTSIAVLGPTFQNLADNVHKNVTDIYYIFVGRSLGYLGGSVLGGILFDHVNAHLLLAFSMLGTTAGLFAIPWCKRSLLLTALMSLIGAAMGVLDTGGNVLALNTWGTEAGPHLQALHFSFAMGAFVAPILAKMAMGNSEPRDLQAGENASQSVLSPVPTASATLALKHHLGVDFLWSYIVIGTYLLFVSFFFFILYSKSSSVRDKSKASAQKCKVAKYHHVLIILLFLFFLCYVGAEVTYGSYIFTYAKVFAEMKESEAAALNSVFWGAFAVCRAVSVFCAACLYPGTMIVLSLIGSAVSSSSLAFFAHYPISLWAGTAVYGASMATIFPSGISWIEQYTVIQGKSASLFVVGAALGEMCIPAVVGYLQGRFHHVPVVMYTALGTSAMTAVLFPVMYKLATASGESSREMSESEDRKALLSSSGLNEDEEDEEDAGEWNEADFEVIEMNDTLRNSVVETSLKAAGDSSSEASLQPHPADAGGDFPVAAGSSPGRKSMNVDREKND", "length": 576, "header": "tr|A0A8V0YKY3-1|A0A8V0YKY3_CHICK Isoform 1 of Major facilitator superfamily domain containing 4B OS=Gallus gallus OX=9031 GN=MFSD4B PE=1 SV=1 CANONICAL=A0A8V0YKY3-1" }, "locus": { "chromosome": "3", "start_pos": 65900214, "end_pos": 65893887, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032865.1", "url": "https://www.ensembl.org/id/ENSGALT00010032865.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019458.1", "url": "https://www.ensembl.org/id/ENSGALP00010019458.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:428623", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:428623", "resource": "KEGG Pathway" }, { "id": "R-GGA-189200", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-189200", "resource": "Reactome", "description": "Cellular hexose transport" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2MLY3-1", "protein_name": "Sodium-dependent glucose transporter 1", "gene_name": "Mfsd4b", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MIGGVLFGCINHFLLLGVSLSATTVGLYLTPFCKTAVLLVIMMSVFGISMGLLDTGGNVLILDLWGDEGAPHMQALHFSFALGAFLAPLLAKLAWGTSASTQNHTEPDFDLLMLNGSSEATSDSLFAVPEDMNLLWAYASIGTYVLVVSVFLFGLFCKKSSRQEKATVSAQEARRAKYHWALLCLLFIFFFFYVGAEVTYGSYVFSFATTHVGMKESEAAGLNSIFWGTFAACRGLAIFFATFLKPGTMIVLCNIGSLTSSLFLVLFDKSPLCLWIATSVYGASMAATFPSGISWIEQYTSISGKSAAFFVIGAALGEMAIPAIIGILQGHYPDLPVVLYTGLGSATFTAVLFPVMYKLATLPLGHQPKGRKSEDQRALLSSSELNDCEEESEEEDAEKWNEMDFEVVEMSDPMQESARDTTGEVLREPTPEASDHFLSKAYFSVSSSDPLVNHQDKRD", "length": 459 }, "evidence": [ { "id": "A0A8V0YKY3", "url": "https://omabrowser.org/oma/group/A0A8V0YKY3/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0AAA9TA10-1", "protein_name": "Major facilitator superfamily domain containing 4B", "gene_name": "MFSD4B", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSLNKILFLNLLHAGGMSVAILGPTFQDLATNVNRNISRLSLIFVGRAFGYLGGSVIGGVLFDSMNHFLLLGVSMFATTVGLYLVPFCKTAVLLIVMMSTFGVSIGILDTGGNVLILAIWGDKGAPHMQALHFSFALGAFLAPLLAKLALGTTVSAENRTEADFNQSAFNQSSEADSESLFGIPDDMNLLWAYAVIGTYIFVVALFFFALFLKKSSKQEKARVSAQRFRRAKYHNALLCLLFLFFFFYVGAEVTYGSYVFSFATTHAGMKEREAAGLNSIFWGTFAACRGMAIFFATCLQPGTMIVLSNIGSLTSSLFLVLFNKSPVCLWIATSVYGASMATTFPSGVSWIEQYTTIHGKAAAFFVVGAALGEMAIPAVIGILQGKYPDLPVVLYTSLGSSIATAILFPVLYKLATLPLDRQRKEHRKSEDQKALLSSSGLNDYEEENEEDDAEKWNEMDFEVIEMNDTMRNSVIETSRNILMEPTAEVPNHSYSNVLMFESSPVNTGNSSVNYLARNQDKRD", "length": 523 }, "evidence": [ { "id": "A0A8V0YKY3", "url": "https://omabrowser.org/oma/group/A0A8V0YKY3/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1LTM4-1", "protein_name": "Major facilitator superfamily domain containing 4B1", "gene_name": "Mfsd4b4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPGARSSAGGAATLELELEFGGAGGQRLLQAGPGAENESEAVASVRSGSAQSVLRWFTTVVLCAAFLGLGLSVAILGPTFPDLARNVNRNISSLSLIFVGRASGYLCGSMIGGVLFDCINHFLLLGMSLSATTVGLYLMPFCKIAALLIVLMSVFGVSMGILDTGGNVLILDLWGDKGAPHMQALHFSFALGAFLAPLLAKLAWGTTASAQNHTESDFISLMLNRTSEAATDSVFAVPDDMNLLWTYASIGTYVLVVSVFLFALFCKKRSRQKKSSASAQGTRRAKYHRALLCLLFLFFFFYVGAEVTYGSYVFSFATTHVGMEESEAAGLNSIFWGTFAACRGLAIFFATCLQPGTMIVVSNIGSLASSFFLVLFDKSPLCLWIASSVYGASMAATFPSGISWIEQYTTLTGKSASFFVIGAALGEMAIPAVIGILQGHYPDLPVVLYTGLGSAIFTAVLFPVMYKLATLPLERQRKGRRKSEDQKALLSSSELHDCEEEIEEEEDAEKWNEMDFEVVEMNDPVQGSVRGTSGDVMGPTAEGSDQFLPDALSFEPLSASSSNSLANH", "length": 568 }, "evidence": [ { "id": "A0A8V0YKY3", "url": "https://omabrowser.org/oma/group/A0A8V0YKY3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "J3QNS5-1", "protein_name": "Major facilitator superfamily domain containing 4B4", "gene_name": "Mfsd4b4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDFNAEGLSVAILGPTFPDLAKNVNRNISSLSLIFVGRASGYLCGSMIGGVLFGCINHFLLLGVSLSATTVGLYLMPFCKTAALLIVMMSVFGVSMGILDTGGNVLILDLWGDKGAPHMQALHFSFALGAFLAPLLAKLAWGTTTSAQNYTEPQSDRLALNQSFEATSDSVFAVPDDMNLLWTYASIGTYVLVVSVFLFGLFCKKHSRQKKPRASAEGARRAKYHRALLCLLFLFFFFYVGAEVTYGSFVFSFAITHVGMEESEAAGLNSIFWGTFAACRGLAIFFATFLQPGTMIVLCNIGSLVSCFFLVLFDKSPLCLWIATSVYGASMAATFPSGISWIEQYTTLTGKSAAFFVIGAALGEMAIPAVIGILQGQYPDLPVVLYTCLGSAIFTAVLFPVMYKLATLPLECQHKGTRKREDQKALLSSSELHDCEEENEEDDAEKWNEMDFEVVEMSDPVQESARETCREEGSGQVLLDGLIAEPFSANSSNSLGNHQDKRD", "length": 503 }, "evidence": [ { "id": "A0A8V0YKY3", "url": "https://omabrowser.org/oma/group/A0A8V0YKY3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q5TF39-1", "protein_name": "Solute carrier family 60 member 2", "gene_name": "SLC60A2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLCASFLGLGLSVAIVGPTFQDLATNVNRNISSLSFIFVGRALGYLSGSVIGGFLVDVMNYFLLLGISMSATTVGLYLVPFCKTAILLTVMMSIFGVSIGILDTGGNVLILAIWGDKGAPHMQALHFSFALGAFLAPLLAKLALGPTASAENHTESDFHPALNQSSDADSEALFGVPNDKNLLWAYAVIGTYMFLVSVIFFCLFLKNSSKQEKARASAETFRRAKYHNALLCLLFLFFFFYVGAEVTYGSYVFSFATTHAGMKESEAAGLNSIFWGTFAACRGLAIFFATCLQPGTMIVLSNIGSLTSSLFLVLFDKNPICLWIATSVYGASMATTFPSGVSWIEQYTTIHGKSAAFFVIGASLGEMAIPAVIGILQGKYPDLPVVLYTSLGASIATGILFPVLYKLATSPLDRQRKEDRKSEDQKALLSSSGLNEYEEENEEEDAEKWNEMDFEMIETNDTMRHSIIETSRSSLTEPTAEVYNQYPSNALVFESSPFNTGSAHVKHLPETRTKGTNV", "length": 518 }, "evidence": [ { "id": "A0A8V0YKY3", "url": "https://omabrowser.org/oma/group/A0A8V0YKY3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKY3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKY3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "transmembrane transporter activity", "id": "GO:0022857", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022857", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YKY3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKY3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 219, "end_pos": 221, "annotation": "n_glycosylation_sequon" }, { "start_pos": 520, "end_pos": 522, "annotation": "n_glycosylation_sequon" }, { "start_pos": 92, "end_pos": 94, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 219, "end_pos": 221 }, { "start_pos": 520, "end_pos": 522 }, { "start_pos": 92, "end_pos": 94 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YL15-1", "uniprot_ac": "A0A8V0YL15", "uniprot_id": "A0A8V0YL15_CHICK", "mass": { "chemical_mass": 114837.0, "monoisotopic_mass": 114837.0 }, "refseq": {}, "gene_names": [ { "name": "TCOF1", "type": "recommended", "evidence": [ { "id": "A0A8V0YL15", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL15" } ] } ], "protein_names": [ { "name": "Treacle ribosome biosis factor 1", "type": "synonym", "evidence": [ { "id": "A0A8V0YL15", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL15/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YL15", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL15" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TCOF1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL15", "locus": { "chromosome": "13", "start_pos": 12754144, "end_pos": 12786511, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013484", "url": "https://www.ensembl.org/id/ENSGALG00010013484" } ] } } ], "crossref": [ { "id": "A0A8V0YL15", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YL15", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR006594", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006594", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017859", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017859", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YL15", "url": "https://www.orthodb.org/?gene=A0A8V0YL15", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YMR5", "url": "https://www.orthodb.org/?gene=A0A8V0YMR5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YSV2", "url": "https://www.orthodb.org/?gene=A0A8V0YSV2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR20787", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR20787", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR20787:SF10", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR20787:SF10", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YL15", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL15", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YL15-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL15-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YMR5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMR5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YMR5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMR5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YSV2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSV2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YSV2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSV2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MARTSLLNLPYGRTWHRTGGLEAHTAHSTQQIQRPSLSSNFRHYISQEAARQEADVTSVSAARGARGSAELGRAMAAEGRGRRELLALIHQHLLRAGYARAARELQAQLGQKLLPSLATSLEEIFTHWEKTPSKARRRKLSDEEAAIPEKIRVPDPVSSSESSEKEEDEKEKTKTGNATSITPVTNSAVNVESSEDDDSSSEEEMPSGKGAITVTPAVASGKAANSLHSPVKPTASGSKAAVPCAANRTVLLNKQQPSASVVTPAKAGQKLPSPGKPGRDAAAVSQAGQSKAPVMTKAPESSSSSSSSESEEEKETPTVKAPAPKVELKQAAGESESSSEESSDETSSEEELATAAVQAKPAVKAVQVNSTPVKSAPATSVSTKKSTVKKRAVTLNQTKHGSVTVPVAAKPDDTSESSDSSDSENEEPPSVTQSKPSLKTSQAILSPVKTTPAASISSKAAPAKTLPLSQGKPTPKPAVLKQAKATPGRTAAPAKPAESANPAESTDSSGSEEDLPVPVSQKRLPEQPGPVPSLNQAAKAMTPEKAVGSTLKNETSESGSSDSSDSEEETPVSQTQPALPAAKSNAVPQPTSVKKVPAPTPAPAPPLHMDSSDDSSEESDSDEEIVPPTQTLSQQNIKPTKVSSTGAAKANATPPSGKGIKAPPIPPISRVSESSNSDSSESSTVVGEAVPPPCPKQTAPMGKAPASPAAPHAASILRSPTAKSKKPGQQPAQDARLSQTAPLTQAEESSDSSSSSDSDEETSKQPPKPGMLQKPGGTEANDSSSSDSSEDEEAVSQSLLTGYMSLSKSPAAPQTPKTVPPQPVGNAGQGKAAVNATSSLAKASVKAAPADSSSSDSSDSDTDVEQVSANHKAESKPPPDEDATGASKKEKGAGKIDVSHANPKPSPVKKALAAKENDVEAKELQANPLPSALLSTPQPEESSLGSKSEVTTAAGVPAVQTPEGLEEKKKKKKEKKEKKEKKKHSSTADKAVKTSKGKDKENKKQKASQKRKRPGEDGAVGQPKEKKRKGQTSEEVPKKKKKKAADDPEKLPGSKEKKKSSKKKKAGKEKKNKKMPTEGESTADGSAEVHKKKKKKKKTAEPEGLL", "length": 1106, "header": "tr|A0A8V0YL15-1|A0A8V0YL15_CHICK Isoform 1 of Treacle ribosome biosis factor 1 OS=Gallus gallus OX=9031 GN=TCOF1 PE=1 SV=1 CANONICAL=A0A8V0YL15-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YL15-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL15/entry#A0A8V0YL15-1", "sequence": { "sequence": "MARTSLLNLPYGRTWHRTGGLEAHTAHSTQQIQRPSLSSNFRHYISQEAARQEADVTSVSAARGARGSAELGRAMAAEGRGRRELLALIHQHLLRAGYARAARELQAQLGQKLLPSLATSLEEIFTHWEKTPSKARRRKLSDEEAAIPEKIRVPDPVSSSESSEKEEDEKEKTKTGNATSITPVTNSAVNVESSEDDDSSSEEEMPSGKGAITVTPAVASGKAANSLHSPVKPTASGSKAAVPCAANRTVLLNKQQPSASVVTPAKAGQKLPSPGKPGRDAAAVSQAGQSKAPVMTKAPESSSSSSSSESEEEKETPTVKAPAPKVELKQAAGESESSSEESSDETSSEEELATAAVQAKPAVKAVQVNSTPVKSAPATSVSTKKSTVKKRAVTLNQTKHGSVTVPVAAKPDDTSESSDSSDSENEEPPSVTQSKPSLKTSQAILSPVKTTPAASISSKAAPAKTLPLSQGKPTPKPAVLKQAKATPGRTAAPAKPAESANPAESTDSSGSEEDLPVPVSQKRLPEQPGPVPSLNQAAKAMTPEKAVGSTLKNETSESGSSDSSDSEEETPVSQTQPALPAAKSNAVPQPTSVKKVPAPTPAPAPPLHMDSSDDSSEESDSDEEIVPPTQTLSQQNIKPTKVSSTGAAKANATPPSGKGIKAPPIPPISRVSESSNSDSSESSTVVGEAVPPPCPKQTAPMGKAPASPAAPHAASILRSPTAKSKKPGQQPAQDARLSQTAPLTQAEESSDSSSSSDSDEETSKQPPKPGMLQKPGGTEANDSSSSDSSEDEEAVSQSLLTGYMSLSKSPAAPQTPKTVPPQPVGNAGQGKAAVNATSSLAKASVKAAPADSSSSDSSDSDTDVEQVSANHKAESKPPPDEDATGASKKEKGAGKIDVSHANPKPSPVKKALAAKENDVEAKELQANPLPSALLSTPQPEESSLGSKSEVTTAAGVPAVQTPEGLEEKKKKKKEKKEKKEKKKHSSTADKAVKTSKGKDKENKKQKASQKRKRPGEDGAVGQPKEKKRKGQTSEEVPKKKKKKAADDPEKLPGSKEKKKSSKKKKAGKEKKNKKMPTEGESTADGSAEVHKKKKKKKKTAEPEGLL", "length": 1106, "header": "tr|A0A8V0YL15-1|A0A8V0YL15_CHICK Isoform 1 of Treacle ribosome biosis factor 1 OS=Gallus gallus OX=9031 GN=TCOF1 PE=1 SV=1 CANONICAL=A0A8V0YL15-1" }, "locus": { "chromosome": "13", "start_pos": 12786056, "end_pos": 12755780, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032539.1", "url": "https://www.ensembl.org/id/ENSGALT00010032539.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019275.1", "url": "https://www.ensembl.org/id/ENSGALP00010019275.1" } ] } }, { "isoform_ac": "A0A8V0YMR5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL15/entry#A0A8V0YMR5-1", "sequence": { "sequence": "MAAEGRGRRELLALIHQHLLRAGYARAARELQAQLGQKLLPSLATSLEEIFTHWEKTPSKARRRKLSDEEAAIPEKIRVPDPVSSSESSEKEEDEKEKTKTGNATSITPVTNSAVNVESSEDDDSSSEEEMPSGKGAITVTPAVASGKAANSLHSPVKPTASGSKAAVPCAANRTVLLNKQQPSASVVTPAKAGQKLPSPGKPGRDAAAVSQAGQSKAPVMTKAPESSSSSSSSESEEEKETPTVKAPAPKVELKQAAGESESSSEESSDETSSEEELATAAVQAKPAVKAVQVNSTPVKSAPATSVSTKKSTVKKRAVTLNQTKHGSVTVPVAAKPDDTSESSDSSDSENEEPPSVTQSKPSLKTSQAILSPVKTTPAASISSKAAPAKTLPLSQGKPTPKPAVLKQAKATPGRTAAPAKPAESANPAESTDSSGSEEDLPVPVSQKRLPEQPGPVPSLNQAAKAMTPEKAVGSTLKNETSESGSSDSSDSEEETPVSQTQPDPLPSSSWFLFLPSKSNAVPQPTSVKKVPAPTPAPAPPLHMDSSDDSSEESDSDEEIVPPTQAVPPPCPKQTAPMGKAPASPAAPHAASILRSPTAKSKKPGQQPAQDARLSQTAPLTQAEESSDSSSSSDSDEETSKQPPKPGMLQKPGGTEANDSSSSDSSEDEEAVSQSLLTGYMSLSKSPAAPQTPKTVPPQPVGNAGQGKAAVNATSSLAKASVKAAPADSSSSDSSDSDTDVEQVSANHKAESKPPPDEDATGASKKEKGAGKIDVSHANPKPSPVKKALAAKENDVEAKELQANPLPSALLSTPQPEESSLGSKSEVTTAAGVPAVQTPEGLEEKKKKKKEKKEKKEKKKHSSTADKAVKTSKGKDKENKKQKASQKRKRPGEDGAVGQPKEKKRKGQTSEEVKEEQKDAHRRGVDSRWLC", "length": 931, "header": "tr|A0A8V0YMR5-1|A0A8V0YMR5_CHICK Computationally mapped isoform of Treacle ribosome biosis factor 1 OS=Gallus gallus OX=9031 GN=TCOF1 PE=1 SV=1 CANONICAL=A0A8V0YL15-1" }, "locus": { "chromosome": "13", "start_pos": 12772356, "end_pos": 12756352, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032475.1", "url": "https://www.ensembl.org/id/ENSGALT00010032475.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019222.1", "url": "https://www.ensembl.org/id/ENSGALP00010019222.1" } ] } }, { "isoform_ac": "A0A8V0YSV2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL15/entry#A0A8V0YSV2-1", "sequence": { "sequence": "MFAAEVSPGRMPHALVPWSCSCKSRRKPGSRTPSKARRRKLSDEEAAIPEKIRVPDPVSSSESSEKEEDEKEKTKTGNATSITPVTNSAVNVESSEDDDSSSEEEMPSGKGAITVTPAVASGKAANSLHSPVKPTASGSKAAVPCAANRTVLLNKQQPSASVVTPAKAGQKLPSPGKPGRDAAAVSQAGQSKAPVMTKAPESSSSSSSSESEEEKETPTVKAPAPKVELKQAAGESESSSEESSDETSSEEELATAAVQAKPAVKAVQVNSTPVKSAPATSVSTKKSTVKKRAVTLNQTKHGSVTVPVAAKPDDTSESSDSSDSENEEPPSVTQSKPSLKTSQAILSPVKTTPAASISSKAAPAKTLPLSQGKPTPKPAVLKQAKATPGRTAAPAKPAESANPAESTDSSGSEEDLPVPVSQKRLPEQPGPVPSLNQAAKAMTPEKAVGSTLKNETSESGSSDSSDSEEETPVSQTQPALPAAKSNAVPQPTSVKKVPAPTPAPAPPLHMDSSDDSSEESDSDEEIVPPTQAVPPPCPKQTAPMGKAPASPAAPHAASILRSPTAKSKKPGQQPAQDARLSQTAPLTQAEESSDSSSSSDSDEETSKQPPKPGMLQKPGGTEANDSSSSDSSEDEEAVSQSLLTGYMSLSKSPAAPQTPKTVPPQPVGNAGQGKAAVNATSSLAKASVKAAPADSSSSDSSDSDTDVEQVSANHKAESKPPPDEDATGASKKEKGAGKIDVSHANPKPSPVKKALAAKENDVEAKELQANPLPSALLSTPQPEESSLGSKSEVTTAAGVPAVQTPEGLEEKKKKKKEKKEKKEKKKHSSTADKAVKTSKGKDKENKKQKASQKRKRPGEDGAVGQPKEKKRKGQTSEEVPKKKKKKAADDPEKLPGSKEKKKSSKKKKAGKEKKNKKMPTEGESTADGSAEVHKKKKKKKKTAEPEGLL", "length": 949, "header": "tr|A0A8V0YSV2-1|A0A8V0YSV2_CHICK Computationally mapped isoform of Treacle ribosome biosis factor 1 OS=Gallus gallus OX=9031 GN=TCOF1 PE=1 SV=1 CANONICAL=A0A8V0YL15-1" }, "locus": { "chromosome": "13", "start_pos": 12771173, "end_pos": 12755780, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032529.1", "url": "https://www.ensembl.org/id/ENSGALT00010032529.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019269.1", "url": "https://www.ensembl.org/id/ENSGALP00010019269.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 215, "start_aa": "Thr", "end_pos": 215, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr215", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 234, "start_aa": "Thr", "end_pos": 234, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr234", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 600, "start_aa": "Thr", "end_pos": 600, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr600", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YL15", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL15" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "scaffold protein binding", "id": "GO:0097110", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097110", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YL15", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL15" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "nucleolar large rRNA transcription by RNA polymerase I", "id": "GO:0042790", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042790", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YL15", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL15" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 177, "end_pos": 179, "annotation": "n_glycosylation_sequon" }, { "start_pos": 247, "end_pos": 249, "annotation": "n_glycosylation_sequon" }, { "start_pos": 369, "end_pos": 371, "annotation": "n_glycosylation_sequon" }, { "start_pos": 396, "end_pos": 398, "annotation": "n_glycosylation_sequon" }, { "start_pos": 553, "end_pos": 555, "annotation": "n_glycosylation_sequon" }, { "start_pos": 651, "end_pos": 653, "annotation": "n_glycosylation_sequon" }, { "start_pos": 781, "end_pos": 783, "annotation": "n_glycosylation_sequon" }, { "start_pos": 835, "end_pos": 837, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 215, 234, 600 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 177, "end_pos": 179 }, { "start_pos": 247, "end_pos": 249 }, { "start_pos": 369, "end_pos": 371 }, { "start_pos": 396, "end_pos": 398 }, { "start_pos": 553, "end_pos": 555 }, { "start_pos": 651, "end_pos": 653 }, { "start_pos": 781, "end_pos": 783 }, { "start_pos": 835, "end_pos": 837 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 3 }, { "field": "total_sites", "count": 3 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 3 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 3 }, { "field": "exact_o_linked_sites", "count": 3 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 3 }, { "field": "total_sites", "count": 3 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 3 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 3 }, { "field": "exact_o_linked_sites", "count": 3 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YL20-1", "uniprot_ac": "A0A8V0YL20", "uniprot_id": "A0A8V0YL20_CHICK", "mass": { "chemical_mass": 65041.0, "monoisotopic_mass": 65041.0 }, "refseq": { "ac": "XP_004945003", "name": "arylsulfatase I", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004945003" }, "gene_names": [ { "name": "ARSI", "type": "recommended", "evidence": [ { "id": "A0A8V0YL20", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL20" } ] }, { "name": "ARSI", "type": "synonym", "evidence": [ { "id": "XP_004945003", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004945003" } ] } ], "protein_names": [ { "name": "Arylsulfatase family member I", "type": "synonym", "evidence": [ { "id": "A0A8V0YL20", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL20/entry#names_and_taxonomy" } ] }, { "name": "arylsulfatase I", "type": "synonym", "evidence": [ { "id": "XP_004945003", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004945003" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052544.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_004945003.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004945003", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004945003" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YL20", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL20" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ARSI", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL20", "locus": { "chromosome": "13", "start_pos": 12792738, "end_pos": 12786642, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013531", "url": "https://www.ensembl.org/id/ENSGALG00010013531" } ] } } ], "crossref": [ { "id": "A0A8V0YL20", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YL20", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd16029", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16029", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "427639", "url": "https://www.ncbi.nlm.nih.gov/gene/427639", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000917", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000917", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017850", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017850", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024607", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024607", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047115", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047115", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:427639", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427639", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WDWMKPS", "url": "https://omabrowser.org/oma/group/WDWMKPS/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YL20", "url": "https://www.orthodb.org/?gene=A0A8V0YL20", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10342", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10342", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10342:SF68", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10342:SF68", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00884", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00884", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-1663150", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1663150", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9840310", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9840310", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_004945003", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004945003", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YL20", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL20", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YL20-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL20-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAVYALTGFSLVSLLSFGYLSWDWMKPGLVADVPTGPMEKSLPPAFARPPHIIFILTDDQGYHDVGYHGSDIQTPTLDRLAAEGVKLENYYIQPICTPSRSQLITGRYQIHTGLQHSIIRPRQPNCLPLDQVTLPQKLQEAGYSTHMVGKWHLGFYKKECLPTRRGFDTFLGSLTGNVDYYTYDNCDGPGVCGYDLHEGENVAWDQSGKYSTFLYAQRVSKILASHSPKEPIFIYVAFQAVHTPLQSPKEYIYRYRSMGNVARRKYAAMVTCMDEAVKNITWALKKYGYYDNSVIVFSTDNGGQTFSGGSNWPLRGRKGTYWEGGVRGIGFVHSPLIKRKRRTSWALVHITDWYPTLVSLARGNLSNVPGLDGYNVWPAISEGKESPRTEILHNIDPLYNHAKYGSLEDGFGIWNTAVQASIRVGEWKLLTGDPGYSDWIPPQTLTNFPGSWWNLERLTDGLRKSVWLFNITADPYERYDLSEQRPDVVRALLTRLVHYNRTAIPVRYPAENPRAHPDFNGGAWGPWASEDEVEEWEGGGGDPPKSQGKKKKCKICKLRSFFRKLNTRLMSNRI", "length": 574, "header": "tr|A0A8V0YL20-1|A0A8V0YL20_CHICK Isoform 1 of Arylsulfatase family member I OS=Gallus gallus OX=9031 GN=ARSI PE=3 SV=1 CANONICAL=A0A8V0YL20-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YL20-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL20/entry#A0A8V0YL20-1", "sequence": { "sequence": "MAVYALTGFSLVSLLSFGYLSWDWMKPGLVADVPTGPMEKSLPPAFARPPHIIFILTDDQGYHDVGYHGSDIQTPTLDRLAAEGVKLENYYIQPICTPSRSQLITGRYQIHTGLQHSIIRPRQPNCLPLDQVTLPQKLQEAGYSTHMVGKWHLGFYKKECLPTRRGFDTFLGSLTGNVDYYTYDNCDGPGVCGYDLHEGENVAWDQSGKYSTFLYAQRVSKILASHSPKEPIFIYVAFQAVHTPLQSPKEYIYRYRSMGNVARRKYAAMVTCMDEAVKNITWALKKYGYYDNSVIVFSTDNGGQTFSGGSNWPLRGRKGTYWEGGVRGIGFVHSPLIKRKRRTSWALVHITDWYPTLVSLARGNLSNVPGLDGYNVWPAISEGKESPRTEILHNIDPLYNHAKYGSLEDGFGIWNTAVQASIRVGEWKLLTGDPGYSDWIPPQTLTNFPGSWWNLERLTDGLRKSVWLFNITADPYERYDLSEQRPDVVRALLTRLVHYNRTAIPVRYPAENPRAHPDFNGGAWGPWASEDEVEEWEGGGGDPPKSQGKKKKCKICKLRSFFRKLNTRLMSNRI", "length": 574, "header": "tr|A0A8V0YL20-1|A0A8V0YL20_CHICK Isoform 1 of Arylsulfatase family member I OS=Gallus gallus OX=9031 GN=ARSI PE=3 SV=1 CANONICAL=A0A8V0YL20-1" }, "locus": { "chromosome": "13", "start_pos": 12790500, "end_pos": 12787493, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032549.1", "url": "https://www.ensembl.org/id/ENSGALT00010032549.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019280.1", "url": "https://www.ensembl.org/id/ENSGALP00010019280.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:427639", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427639", "resource": "KEGG Pathway" }, { "id": "R-GGA-1663150", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1663150", "resource": "Reactome", "description": "The activation of arylsulfatases" }, { "id": "R-GGA-9840310", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9840310", "resource": "Reactome", "description": "Glycosphingolipid catabolism" } ], "orthologs": [ { "uniprot_canonical_ac": "E1BIN3-1", "protein_name": "Arylsulfatase family member I", "gene_name": "ARSI", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAMQALTGFSLVSLLGFGYLSWDWAKPSLVADAPAEAGVEHPSAAPPQPPHIIFILTDDQGYHDVGYHGSDIETPTLDRLAAEGVKLENYYIQPICTPSRSQLLTGRYQIHTGLQHSIIRPRQPNCLPLDQVTLPQKLQELGYSTHMVGKWHLGFYRKECLPTRRGFDTFLGSLTGNVDYYTYDNCDGPGVCGFDLHEGENVAWGLSGQYSTLLYAQRVSHILASHSPRQPLFLYVAFQAVHTPLQSPREYLYRYRTMGNVARRKYAAMVTCMDEAVRNITWALKRHGFYNNSVIIFSSDNGGQTFSGGSNWPLRGRKGTYWEGGVRGLGFVHSPLLKRKRRTSRALVHITDWYPTLVALAGGTASAADGLDGYDVWPAISEGRASPRTEILHNIDPLYNHARHGSLEGGFGIWNTAVQAAIRVGEWKLLTGDPGYGDWIPPQTLAAFPGSWWNLERMASARQAVWLFNISADPYEREDLAGQRPDVVRALLARLVDYNRTAIPVRYPAENPRAHPDFNGGAWGPWASDEEEDEEEEEGRAQSQSRGRRKKKCKICKLRSFFRKLNTRLMSHRI", "length": 574 }, "evidence": [ { "id": "A0A8V0YL20", "url": "https://omabrowser.org/oma/group/A0A8V0YL20/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "E7F4Z7-1", "protein_name": "Arylsulfatase I", "gene_name": "arsia", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAVRALLALSVLAYLGAADLTQDWTGPNQVEQPNHARPHIIFIMTDDQGFNDIGYHNTDIHTPTLDRLAAAGVKLENYYIQPICTPSRSQFITGRYQIHTGLQHSIIRSRQPSCLPFGLRTLPQRLQEAGYATHMVGKWHLGFYKRDCLPTRRGFNTYFGSLTGSVDYYTYKSCDGPKVCGFDLHDGERVAWGQGGRYSTHLYTQRVRKILAAHDPSSQPLFIFLSFQAVHTPLQSPKEYVYPYRRMGNMFRRKYAGMVSAVDEAVRNVTYALRKYGYYKNTVIFFSTDNGGQPLFGGSNWPLRGRKGTYWEGGVRGIGFVHSPLLRRRRRVSRALIHITDWYPTLMRLAGGNVSQAEGLDGFDMWDTISDGKESPRFEILHNIDPLYNAARHGSLKNGYGIWNTAVQAAVRVGDWKLLTGNPGYGDWIPPQMLGNFPESWWSLERHTEAKKSLWLFNVADDPYERFDLAERRPDVVKQLLARLSFYNRTAVPVRYPSEDPRADPSRNGGAWGPWEGDGENWEPFYIKKKKAKKQKRKFCKMKSFFRRLNIRIMSNRI", "length": 558 }, "evidence": [ { "id": "A0A8V0YL20", "url": "https://omabrowser.org/oma/group/A0A8V0YL20/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q32KI9-1", "protein_name": "Arylsulfatase I", "gene_name": "Arsi", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MHALSGFSLVSLLSLGYLSWDWAKPGLVADGPAEAGDQPSVAPPQPPHIIFILTDDQGYHDVGYHGSDIETPTLDRLAAEGVKLENYYIQPICTPSRSQLLTGRYQIHTGLQHSIIRPRQPNCLPLDQVTLPQKLQEAGYSTHMVGKWHLGFYRKECLPTRRGFDTFLGSLTGNVDYYTYDNCDGPGVCGFDLHEGESVAWGLSGQYSTMLYAQRASHILASHNPQNPLFLYVAFQAVHTPLQSPREYLYRYRTMGNVARRKYAAMVTCMDEAVRNITWALKRYGFYNNSVIIFSSDNGGQTFSGGSNWPLRGRKGTYWEGGVRGLGFVHSPLLKKKRRTSRALVHITDWYPTLVGLAGGTTSAADGLDGYDVWPAISEGRASPRTEILHNIDPLYNHARHGSLEGGFGIWNTAVQAAIRVGEWKLLTGDPGYGDWIPPQTLASFPGSWWNLERMASIRQAVWLFNISADPYEREDLAGQRPDVVRTLLARLADYNRTAIPVRYPAANPRAHPDFNGGAWGPWASEEEEEEEEEEEEGRARSFSRGRRKKKCKICKLRSFFRKLNTRLMSHRI", "length": 573 }, "evidence": [ { "id": "A0A8V0YL20", "url": "https://omabrowser.org/oma/group/A0A8V0YL20/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q32KJ8-1", "protein_name": "Arylsulfatase I", "gene_name": "Arsi", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MHALSGFSLVSLLSLGYLSWDWAKPGLVADGPAEAEDQPSAAPPQPPHIIFILTDDQGYHDVGYHGSDIETPTLDRLAAEGVKLENYYIQPICTPSRSQLLTGRYQIHTGLQHSIIRPRQPNCLPLDQVTLPQKLQEAGYSTHMVGKWHLGFYRKECLPTRRGFDTFLGSLTGNVDYYTYDNCDGPGVCGFDLHEGESVAWGLSGQYSTMLYAQRASHILASHSPQKPLFLYVAFQAVHTPLQSPREYLYRYRTMGNVARRKYAAMVTCMDEAVRNITWALKRYGFYNNSVIIFSSDNGGQTFSGGSNWPLRGRKGTYWEGGVRGLGFVHSPLLKKKRRTSRALVHITDWYPTLVGLAGGTTSAADGLDGYDVWPAISEGRASPRTEILHNIDPLYNHARHGSLEGGFGIWNTAVQAAIRVGEWKLLTGDPGYGDWIPPQTLASFPGSWWNLERMASIRQAVWLFNISADPYEREDLADQRPDVVRTLLARLADYNRTAIPVRYPAANPRAHPDFNGGAWGPWASDEDEEEEDEEEEGRARSFPRGRRKKKCKICKLRSFFRKLNTRLMSHRI", "length": 573 }, "evidence": [ { "id": "A0A8V0YL20", "url": "https://omabrowser.org/oma/group/A0A8V0YL20/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5FYB1-1", "protein_name": "Arylsulfatase I", "gene_name": "ARSI", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MHTLTGFSLVSLLSFGYLSWDWAKPSFVADGPGEAGEQPSAAPPQPPHIIFILTDDQGYHDVGYHGSDIETPTLDRLAAKGVKLENYYIQPICTPSRSQLLTGRYQIHTGLQHSIIRPQQPNCLPLDQVTLPQKLQEAGYSTHMVGKWHLGFYRKECLPTRRGFDTFLGSLTGNVDYYTYDNCDGPGVCGFDLHEGENVAWGLSGQYSTMLYAQRASHILASHSPQRPLFLYVAFQAVHTPLQSPREYLYRYRTMGNVARRKYAAMVTCMDEAVRNITWALKRYGFYNNSVIIFSSDNGGQTFSGGSNWPLRGRKGTYWEGGVRGLGFVHSPLLKRKQRTSRALMHITDWYPTLVGLAGGTTSAADGLDGYDVWPAISEGRASPRTEILHNIDPLYNHAQHGSLEGGFGIWNTAVQAAIRVGEWKLLTGDPGYGDWIPPQTLATFPGSWWNLERMASVRQAVWLFNISADPYEREDLAGQRPDVVRTLLARLAEYNRTAIPVRYPAENPRAHPDFNGGAWGPWASDEEEEEEEGRARSFSRGRRKKKCKICKLRSFFRKLNTRLMSQRI", "length": 569 }, "evidence": [ { "id": "A0A8V0YL20", "url": "https://omabrowser.org/oma/group/A0A8V0YL20/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YL20", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL20" } ], "pmid": "" }, { "name": "sulfuric ester hydrolase activity", "id": "GO:0008484", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008484", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YL20", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL20" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 279, "end_pos": 281, "annotation": "n_glycosylation_sequon" }, { "start_pos": 364, "end_pos": 366, "annotation": "n_glycosylation_sequon" }, { "start_pos": 470, "end_pos": 472, "annotation": "n_glycosylation_sequon" }, { "start_pos": 500, "end_pos": 502, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YL20", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL20" }, { "id": "PF00884", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00884" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Sulfatase N-terminal", "eco_id": "ECO_0000259", "start_pos": 50, "end_pos": 361, "start_aa": "Pro", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 279, "end_pos": 281 }, { "start_pos": 364, "end_pos": 366 }, { "start_pos": 470, "end_pos": 472 }, { "start_pos": 500, "end_pos": 502 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YL29-1", "uniprot_ac": "A0A8V0YL29", "uniprot_id": "A0A8V0YL29_CHICK", "mass": { "chemical_mass": 61331.0, "monoisotopic_mass": 61331.0 }, "refseq": { "ac": "XP_040517941", "name": "protein downstream neighbor of Son", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040517941" }, "gene_names": [ { "name": "DONSON", "type": "recommended", "evidence": [ { "id": "A0A8V0YL29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL29" } ] }, { "name": "DONSON", "type": "synonym", "evidence": [ { "id": "XP_040517941", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040517941" } ] } ], "protein_names": [ { "name": "DNA replication fork stabilization factor DONSON", "type": "synonym", "evidence": [ { "id": "A0A8V0YL29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL29/entry#names_and_taxonomy" } ] }, { "name": "protein downstream neighbor of Son", "type": "synonym", "evidence": [ { "id": "XP_040517941", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040517941" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052573.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040517941", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040517941" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YL29", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL29" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "DONSON", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL29", "locus": { "chromosome": "1", "start_pos": 105527678, "end_pos": 105533327, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012105", "url": "https://www.ensembl.org/id/ENSGALG00010012105" } ] } } ], "crossref": [ { "id": "A0A8V0YL29", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YL29", "database": "AlphaFoldDB", "categories": [] }, { "id": "418504", "url": "https://www.ncbi.nlm.nih.gov/gene/418504", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR024861", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024861", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:418504", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418504", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WCLKTRV", "url": "https://omabrowser.org/oma/group/WCLKTRV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YL29", "url": "https://www.orthodb.org/?gene=A0A8V0YL29", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12972", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12972", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12972:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12972:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF27662", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF27662", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_040517941", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040517941", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YL29", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL29", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YL29-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL29-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDATVPGYSPGFKKPPATLRLKRKRPRRSEPAAPQPCGAAPRAPSAPARRNPFSSLDNAPRQPGRRHQGEPAPPGGGPASAAPFWQFLESAGEDEPARSVGLSEGTNVLALPEDLHLPVPTPTVPTSPKHEFPADWSIKTRLLFTSSQPFTWAEHLKAQEEAQGFAQHCRAAEINLPQSVQEPKLSTELRCAFQQSLVYWLHPSLPWLQLFPRIGADRKIAGKACPWAQDEALQQALMSDWSVSFTSLYNLLKAKLCPYFYVCTYQFTVLFRAAGLAGSDVITAVLSPTTRGLREAMRNEGIEFSLPLVEESRSKKQKNSEGNLETEVAHGPEVDRSPEDGKEAAPSDDDDDGFSWLEEMGVQDKVKKPDAISIKLRKEKHEVQVDHRPESLAVVKGTNTFTLLNFLINCKSLVAVAGPQAGLPPTLLSPVAFRGGTMQTLKARSMNAKARVRLAYEDIFSLEIVGPVLPHSLHSLTMLLQSAQQGAFSAVLYTYEPTAVFNTHLDNASAALKKETISKDLLKCGLHSKTLDQLSQVPTLGKSSLRSLEMKDYAYAWKS", "length": 559, "header": "tr|A0A8V0YL29-1|A0A8V0YL29_CHICK Isoform 1 of DNA replication fork stabilization factor DONSON OS=Gallus gallus OX=9031 GN=DONSON PE=3 SV=1 CANONICAL=A0A8V0YL29-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YL29-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL29/entry#A0A8V0YL29-1", "sequence": { "sequence": "MDATVPGYSPGFKKPPATLRLKRKRPRRSEPAAPQPCGAAPRAPSAPARRNPFSSLDNAPRQPGRRHQGEPAPPGGGPASAAPFWQFLESAGEDEPARSVGLSEGTNVLALPEDLHLPVPTPTVPTSPKHEFPADWSIKTRLLFTSSQPFTWAEHLKAQEEAQGFAQHCRAAEINLPQSVQEPKLSTELRCAFQQSLVYWLHPSLPWLQLFPRIGADRKIAGKACPWAQDEALQQALMSDWSVSFTSLYNLLKAKLCPYFYVCTYQFTVLFRAAGLAGSDVITAVLSPTTRGLREAMRNEGIEFSLPLVEESRSKKQKNSEGNLETEVAHGPEVDRSPEDGKEAAPSDDDDDGFSWLEEMGVQDKVKKPDAISIKLRKEKHEVQVDHRPESLAVVKGTNTFTLLNFLINCKSLVAVAGPQAGLPPTLLSPVAFRGGTMQTLKARSMNAKARVRLAYEDIFSLEIVGPVLPHSLHSLTMLLQSAQQGAFSAVLYTYEPTAVFNTHLDNASAALKKETISKDLLKCGLHSKTLDQLSQVPTLGKSSLRSLEMKDYAYAWKS", "length": 559, "header": "tr|A0A8V0YL29-1|A0A8V0YL29_CHICK Isoform 1 of DNA replication fork stabilization factor DONSON OS=Gallus gallus OX=9031 GN=DONSON PE=3 SV=1 CANONICAL=A0A8V0YL29-1" }, "locus": { "chromosome": "1", "start_pos": 105533275, "end_pos": 105527955, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029014.1", "url": "https://www.ensembl.org/id/ENSGALT00010029014.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016773.1", "url": "https://www.ensembl.org/id/ENSGALP00010016773.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 121, "start_aa": "Thr", "end_pos": 121, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr121", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 123, "start_aa": "Thr", "end_pos": 123, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr123", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:418504", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418504", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287BJG1-1", "protein_name": "DNA replication fork stabilization factor DONSON", "gene_name": "DONSON", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MALSVPGYSPSFKRPPETLRLRRKRGRSLGAAPPPKERPEQTTRRAALAAGLPLRPFPAAASRGGGAPAAARRNPFARLDNRPRAASEPPDGPPRSQQEAPGPRLDSNQENDLLWEEKFSERRAISEFLQIPHVSFSESDIPSSESTELPVDWSIKTRLLFTSSQPFTWADHLKAQEEAQGVIQHCRATEVTLPQSIQDPKLCTELRCAFQQSLIYWIHPAFPWLPLFPRIGADRKMAGKANPWSNDETLQHNLLSDWSVSLTSLYNLLKTKLCPYFYVCTYQFTILFRAAGLAGNDVMTALISPTTRGIREAMKTEGIEFSLPLIKENGHEKKEASGTGLGHGEGQAVSDEDEEESFSWLEEMGVQDKIKKPDVLSIKLRKEKHEVQMDHRPESVVLVKGMNTFTLLNFLINCKSLVASSGPQAGLPPTLLSPIAFRGATMQMLKARSVNVKTQALSGYKDQFSLEITGPVMPHSLHSVTMLLKSSQSGSFSAGLYTHEPTAVFNTCLPTDKVLDREAVLEELSNCGLHPKTLDHLSQTPVLGKSSLRHVEMSDCMYNWRS", "length": 562 }, "evidence": [ { "id": "A0A8V0YL29", "url": "https://omabrowser.org/oma/group/A0A8V0YL29/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "E9PSU2-1", "protein_name": "DNA replication fork stabilization factor DONSON", "gene_name": "Donson", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAVSVPGYSPSFKRPPEVVRLRRKRPRDHGTAVSSALPEPALRRAALAAGLPLRPFPTAGGRGGATTTIARRNPFARLDNRPRVADEAPEEPLRGPQGAPGPLLDSNGENNLLWEEASHERTVTELSQSQQVTLSESDTWSSDGTELPVDWSIKTRLLFTSSQPFSWAEHLKAQEEAQGLVQHCRATEVTLPQSIPDPKLSTVLRCAFQQTLVYWLHPAFSWLPLFPRIGADRKMAAKTSPWSTDESLQHALMSDWSVSFTSLYNLLKTKLCPYFYVCSYQFTVLFRAAGLAGSSVITALITPTTRGLREAMKSEGIEFSLPLLEESGHKEKVREPSLESEEEQAVSDEDEEESLSWLEEIGVQDQIKKPDLISVKLRKEKHEVQMDHRPESVVLVKGLNTFKLLNFLINCKSLVATSGAQAGLPPTLLSPVAFRGASMQMLKARSINVKTQALFGYRDKFSLEITGPVMPHALHSVAMLLRSSQRGSFSAGLYAHEPTAVFNVGLPLDKELDRKGAHKDLANCGLHPKTLEQLSQMPVLGKSSLRNVEMSDYIVNWRS", "length": 559 }, "evidence": [ { "id": "A0A8V0YL29", "url": "https://omabrowser.org/oma/group/A0A8V0YL29/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F6RSI9-1", "protein_name": "DNA replication fork stabilization factor DONSON", "gene_name": "DONSON", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAWMTRANAPPRTRRERLGDGPARGPHRARAMSGSGAGSRGGGARTRGNLLPGCPPRPPPGVMDLSVPGYSPSFKRPPETLRLRRKRGRSLGAAERPEPATRRAARAAGLPLRPFPAAGRGGGGGPAGARRNPFARLDNRPRAASEPPEGPPRGQQEAPGRFLDSNQENDLLWEEKVPERTAITELHQTPHVSFSESDIPPSESTELPVDWSIKTRLLFTSSQPFTWADHLKAQEEAQGIIQHCRATEVTLPQSIQDPKLSTELRCAFQRSLIYWLHPALSWLPLFPRIGADRKMAGKTTPWSNDETLQHVLMSDWSVSFTSLYNLLKTKLCPYFYVCTYQFTILFRAAGLAGDDVITALISPTTRGIREAMKNEGIEFSLPLIKENGPEKRKASGTGLRHGEEQAISDEDEEESFSWLEEMGVQDKIKKPDVLSIKLRKEIHEVQMDHRPESVVLVKGMNTFTLLNFLINCKSLIATSGPQAGLPPTLLSPVAFRGATMQMLKARSVNVKTQALSGYRNQFSLEITGPIMPHSLHSVTMLLQSSQNGSFSAGLYTHEPTAVFNICPPKDNVLDKEAVHEELANCGLHPKTLDHLCRTPVLGKLSLRHVEMSDYIYNWRS", "length": 620 }, "evidence": [ { "id": "A0A8V0YL29", "url": "https://omabrowser.org/oma/group/A0A8V0YL29/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q9NYP3-1", "protein_name": "Protein downstream neighbor of Son", "gene_name": "DONSON", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MALSVPGYSPGFRKPPEVVRLRRKRARSRGAAASPPRELTEPAARRAALVAGLPLRPFPAAGGRGGGSGGGPAAARRNPFARLDNRPRVAAEPPDGPAREQPEAPVPFLDSNQENDLLWEEKFPERTTVTELPQTSHVSFSEPDIPSSKSTELPVDWSIKTRLLFTSSQPFTWADHLKAQEEAQGLVQHCRATEVTLPKSIQDPKLSSELRCTFQQSLIYWLHPALSWLPLFPRIGADRKMAGKTSPWSNDATLQHVLMSDWSVSFTSLYNLLKTKLCPYFYVCTYQFTVLFRAAGLAGSDLITALISPTTRGLREAMRNEGIEFSLPLIKESGHKKETASGTSLGYGEEQAISDEDEEESFSWLEEMGVQDKIKKPDILSIKLRKEKHEVQMDHRPESVVLVKGINTFTLLNFLINSKSLVATSGPQAGLPPTLLSPVAFRGATMQMLKARSVNVKTQALSGYRDQFSLEITGPIMPHSLHSLTMLLKSSQSGSFSAVLYPHEPTAVFNICLQMDKVLDMEVVHKELTNCGLHPNTLEQLSQIPLLGKSSLRNVVLRDYIYNWRS", "length": 566 }, "evidence": [ { "id": "A0A8V0YL29", "url": "https://omabrowser.org/oma/group/A0A8V0YL29/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9QXP4-1", "protein_name": "Protein downstream neighbor of Son", "gene_name": "Donson", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAVSVPGYSPSFKRPPETVRLRRKRSRDHGAAVPASLPEPAPRRAALAAGLPLRPFPTAGGRGGAAATIARRNPFARLDNRPRVSDEASEEPLRGPQGASGPLLDSNEENNLLWEDTSSHERTGTELSQSQRVSLSESDTWSSDGTELPVDWSIKTRLLFTSSQPFSWADHLKAQEEAQGLVQHCRATEVTLPQSIQDPKLSTALRCAFQQALVYWLHPAFSWLPLFPRIGADRKMAAKTSPWSADETLQHALMSDWSVSFTSLYNLLKTKLCPYFYVCSYQFTVLFRAAGLAGSSVITALISPTTRGLREAMRNEGIEFSLPLLEEIGHKKKVRDPSLESEEEQAVSDEDEEESFSWLEEIGVQDQIKKPDVISIKLRKEKHEVQMDHRPESVVLVKGLNTFKLLNFLINCKSLVATSGAQAGLPPTLLSPIAFRGASMQMLKARSSNVKTQALSGYRDKFSLDITGPVMPHALHSMSMLLRSSQRGSFSAGLYAHEPTAVFNVGLSLDKELDRKVAREDLANCGLHPKTLEQLSQRPVLGKSSLRSVEMSDYILSWRS", "length": 560 }, "evidence": [ { "id": "A0A8V0YL29", "url": "https://omabrowser.org/oma/group/A0A8V0YL29/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VNA8-1", "protein_name": "Protein downstream neighbor of son homolog", "gene_name": "hd", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSTEASVASKWTRPDDFIKLQRLKQKKNKLAARVSNNNNRRPRHQVDETDKSKLLEAKLAQKRKNPFAKSTADAKKLRVDPQLADLEPVVTASSCFVRETPTRPAPAKFVLQKYDPQAFAKLFQHPQINAEDEDDAELAARQKHTAHLPVDWSLKTRARFFCPTELPAIQLKTSQLASGLTSFVRCMDPQRTESTLDISDATRFNQCNYYWQHPHLPWLTLYPRTAKENVGVVVGERERKALAEEWDFSFRGLFQLLRARQCPYFYLCANTFTVLFRAAGVGGRPESHALVTPSTRGMRQALRQEGIEFSMPLKSDNSGNAHDNSFNEESTTTSLGPEAGEDAPPPAQEDEDDDEDWLESLGVDERELRRIQSSHARKQQAAEMREDFSDNSLLLVDGVECQGFFSYLLNAKSAISTVGRLAGVPPTLLSPVAFPKATMQHLVPRSKKVRLDGVDYFSIDIKGLILPTFLPSVAELLSETRQMFSSTLASSINTLAFSKATQKLLETPETPQSDAEGEDAAGQVFGEQNLSECGLLPAVVGSICRTGQHAVGLLERVCYQRDEGYAWS", "length": 568 }, "evidence": [ { "id": "A0A8V0YL29", "url": "https://omabrowser.org/oma/group/A0A8V0YL29/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "replisome", "id": "GO:0030894", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030894", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YL29", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL29" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YL29", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL29" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "mitotic G2 DNA damage checkpoint signaling", "id": "GO:0007095", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007095", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YL29", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL29" } ], "pmid": "" }, { "name": "nuclear DNA replication", "id": "GO:0033260", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033260", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YL29", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL29" } ], "pmid": "" }, { "name": "replication fork processing", "id": "GO:0031297", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031297", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YL29", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL29" } ], "pmid": "" }, { "name": "mitotic DNA replication checkpoint signaling", "id": "GO:0033314", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033314", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YL29", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL29" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 507, "end_pos": 509, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 121, 123 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 507, "end_pos": 509 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YL30-1", "uniprot_ac": "A0A8V0YL30", "uniprot_id": "A0A8V0YL30_CHICK", "mass": { "chemical_mass": 127836.0, "monoisotopic_mass": 127836.0 }, "refseq": { "ac": "XP_004945087", "name": "AF4/FMR2 family member 4 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004945087" }, "gene_names": [ { "name": "AFF4", "type": "recommended", "evidence": [ { "id": "A0A8V0YL30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL30" } ] }, { "name": "AFF4", "type": "synonym", "evidence": [ { "id": "XP_004945087", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004945087" } ] } ], "protein_names": [ { "name": "AF4/FMR2 family member 4 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_004945087", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004945087" } ] }, { "name": "ALF transcription elongation factor 4", "type": "synonym", "evidence": [ { "id": "A0A8V0YL30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL30/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052544.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004945087", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004945087" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YL30", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL30" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "AFF4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL30", "locus": { "chromosome": "13", "start_pos": 16688518, "end_pos": 16732631, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013737", "url": "https://www.ensembl.org/id/ENSGALG00010013737" } ] } } ], "crossref": [ { "id": "A0A8V0YL30", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YL30", "database": "AlphaFoldDB", "categories": [] }, { "id": "416337", "url": "https://www.ncbi.nlm.nih.gov/gene/416337", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR007797", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007797", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043639", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043639", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043640", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043640", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:416337", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416337", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HTREPQK", "url": "https://omabrowser.org/oma/group/HTREPQK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YL30", "url": "https://www.orthodb.org/?gene=A0A8V0YL30", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YLL1", "url": "https://www.orthodb.org/?gene=A0A8V0YLL1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10528", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10528", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10528:SF15", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10528:SF15", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05110", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05110", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF18875", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18875", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF18876", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18876", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-112382", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-112382", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-674695", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-674695", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-75955", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-75955", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_004945087", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004945087", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YL30", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL30", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YL30-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL30-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLL1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLL1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLL1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLL1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNREDRNVLRMKERERRNQEIQQGEEAFPPNSPLFAEPYKVTSKEDKLSSRIQSMLGNYDEMDDLIGDRSLPKLVGIPKPTVPSTADEKSNQSFFGDQRHNASSHQSSKWTPVGPAPSTSSQSQKRSSGLQSGHSGQRGGGNNTSSGGQRHDRDSYSSSSSRKKSQHGSEHSKSRSSSPGKPPAVSSLSSSHSRSHGSDHHSKEHQRSKSPRDPDANWDSPSRVPSFSSGQHSNQSFPPSLMSKSSSMLQKPTAYVRPMDGQESMEPKLSSEHYSSQTHSSGVNELKPSSKAHLTKLKIPSQPLDASASGDVSCVDEILKEMTHSWPPPLTAIHTPCKTEPSKFPFPTKESQQSSFGTGEQKRYNPSSKTSNGHQSKSCESNQTDMLKDDLKLSSSEDSDGEQDCDKTVPRSTPGSSSEPSQHNSEGADNSRDDSSSHSGSESSSGSDSESESSSSDSEANEPSQSASPEPEPPPTNKWQLDNWLNKVNSHKVSPASSVDSNIPSSQGYKKEGRDQGTGSGYTDQSGSKDSISSTPGRDSKPTQKGSESSRGRQKSPAQSDSSTQRRTVGKKQPKKAEKTSVEEPRGGLKIESETPVDMATNIPSNRHKAATKGSRKPNIKKEPKSSPRPTTEKKKYKASSKSAQKSREFIETDTSSSDSDENESLPPSSQTPKYSESNRTPVKSSMEEDDSFFRQRMFSPMEEKELLSPLSDPDERYPLIVKIDLSLLSRIPGKPYKDADVPKVEKKNVPEKHARESQKQPSDKSSTKGKRKHKQNEDENRASESKKTKLEEKAPSGHKTSSSRESLKPSAVKEKDLLPSPAAPVLQKDSKQEHGSRKRTVSQSSSLKSSSNVSKDSSSGSKSSSSSKQKKMEGKGSGSAKETKEKILNNSSNCPPVSAPSTESSKSRRAKLVFDDRTYSADHYLQEAKKLKHNADALSDRFEKAVYYLDAVVSFIECGNALEKNAQESKSPFPMYSETVELIKYTMKLKNYLAPDATAADKRLAVLCLRCQSLLYLRLFKLKKESALKYSKTLTEHLKNSYNNSQAPSPGMGSKPVGMPSPVSPKLSPGNSGNYSSGTANPSGSGSSVMIPQRIHQMAASYVQVTSNFLYATEIWDQAEQLSKEQKEFFAELDKAMGPLVFNSSIMTDLVRYTRQGLHWLRLDAK", "length": 1167, "header": "tr|A0A8V0YL30-1|A0A8V0YL30_CHICK Isoform 1 of ALF transcription elongation factor 4 OS=Gallus gallus OX=9031 GN=AFF4 PE=3 SV=1 CANONICAL=A0A8V0YL30-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YL30-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL30/entry#A0A8V0YL30-1", "sequence": { "sequence": "MNREDRNVLRMKERERRNQEIQQGEEAFPPNSPLFAEPYKVTSKEDKLSSRIQSMLGNYDEMDDLIGDRSLPKLVGIPKPTVPSTADEKSNQSFFGDQRHNASSHQSSKWTPVGPAPSTSSQSQKRSSGLQSGHSGQRGGGNNTSSGGQRHDRDSYSSSSSRKKSQHGSEHSKSRSSSPGKPPAVSSLSSSHSRSHGSDHHSKEHQRSKSPRDPDANWDSPSRVPSFSSGQHSNQSFPPSLMSKSSSMLQKPTAYVRPMDGQESMEPKLSSEHYSSQTHSSGVNELKPSSKAHLTKLKIPSQPLDASASGDVSCVDEILKEMTHSWPPPLTAIHTPCKTEPSKFPFPTKESQQSSFGTGEQKRYNPSSKTSNGHQSKSCESNQTDMLKDDLKLSSSEDSDGEQDCDKTVPRSTPGSSSEPSQHNSEGADNSRDDSSSHSGSESSSGSDSESESSSSDSEANEPSQSASPEPEPPPTNKWQLDNWLNKVNSHKVSPASSVDSNIPSSQGYKKEGRDQGTGSGYTDQSGSKDSISSTPGRDSKPTQKGSESSRGRQKSPAQSDSSTQRRTVGKKQPKKAEKTSVEEPRGGLKIESETPVDMATNIPSNRHKAATKGSRKPNIKKEPKSSPRPTTEKKKYKASSKSAQKSREFIETDTSSSDSDENESLPPSSQTPKYSESNRTPVKSSMEEDDSFFRQRMFSPMEEKELLSPLSDPDERYPLIVKIDLSLLSRIPGKPYKDADVPKVEKKNVPEKHARESQKQPSDKSSTKGKRKHKQNEDENRASESKKTKLEEKAPSGHKTSSSRESLKPSAVKEKDLLPSPAAPVLQKDSKQEHGSRKRTVSQSSSLKSSSNVSKDSSSGSKSSSSSKQKKMEGKGSGSAKETKEKILNNSSNCPPVSAPSTESSKSRRAKLVFDDRTYSADHYLQEAKKLKHNADALSDRFEKAVYYLDAVVSFIECGNALEKNAQESKSPFPMYSETVELIKYTMKLKNYLAPDATAADKRLAVLCLRCQSLLYLRLFKLKKESALKYSKTLTEHLKNSYNNSQAPSPGMGSKPVGMPSPVSPKLSPGNSGNYSSGTANPSGSGSSVMIPQRIHQMAASYVQVTSNFLYATEIWDQAEQLSKEQKEFFAELDKAMGPLVFNSSIMTDLVRYTRQGLHWLRLDAK", "length": 1167, "header": "tr|A0A8V0YL30-1|A0A8V0YL30_CHICK Isoform 1 of ALF transcription elongation factor 4 OS=Gallus gallus OX=9031 GN=AFF4 PE=3 SV=1 CANONICAL=A0A8V0YL30-1" }, "locus": { "chromosome": "13", "start_pos": 16715611, "end_pos": 16688976, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032963.1", "url": "https://www.ensembl.org/id/ENSGALT00010032963.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019493.1", "url": "https://www.ensembl.org/id/ENSGALP00010019493.1" } ] } }, { "isoform_ac": "A0A8V0YLL1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL30/entry#A0A8V0YLL1-1", "sequence": { "sequence": "MNREDRNVLRMKERERRNQEIQQGEEAFPPNSPLFAEPYKVTSKEDKLSSRIQSMLGNYDEMDDLIGDRSLPKLVGIPKPTVPSTADEKSNQSFFGDQRHNASSHQSSKWTPVGPAPSTSSQSQKRSSGLQSGHSGQRGGGNNTSSGGQRHDRDSYSSSSSRKKSQHGSEHSKSRSSSPGKPPAVSSLSSSHSRSHGSDHHSKEHQRSKSPRDPDANWDSPSRVPSFSSGQHSNQSFPPSLMSKSSSMLQKPTAYVRPMDGQESMEPKLSSEHYSSQTHSSGVNELKPSSKAHLTKLKIPSQPLDASASGDVSCVDEILKEMTHSWPPPLTAIHTPCKTEPSKFPFPTKESQQSSFGTGEQKRYNPSSKTSNGHQSKSCESNQTDMLKDDLKLSSSEDSDGEQDCDKTVPRSTPGSSEPSQHNSEGADNSRDDSSSHSGSESSSGSDSESESSSSDSEANEPSQSASPEPEPPPTNKWQLDNWLNKVNSHKVSPASSVDSNIPSSQGYKKEGRDQGTGSGYTDQSGSKDSISSTPGRDSKPTQKGSESSRGRQKSPAQSDSSTQRRTVGKKQPKKAEKTSVEEPRGGLKIESETPVDMATNIPSNRHKAATKGSRKPNIKKEPKSSPRPTTEKKKYKASSKSAQKSREFIETDTSSSDSDENESLPPSSQTPKYSESNRTPVKSSMEEDDSFFRQRMFSPMEEKELLSPLSDPDERYPLIVKIDLSLLSRIPGKPYKDADVPKVEKKNVPEKHARESQKQPSDKSSTKGKRKHKQNEDENRASESKKTKLEEKAPSGHKTSSSRESLKPSAVKEKDLLPSPAAPVLQKDSKQEHGSRKRTVSQSSSLKSSSNVSKDSSSGSKSSSSSKQKKMEGKGSGSAKETKEKILNNSSNCPPVSAPSTESSKSRRAKLVFDDRTYSADHYLQEAKKLKHNADALSDRFEKAVYYLDAVVSFIECGNALEKNAQESKSPFPMYSETVELIKYTMKLKNYLAPDATAADKRLAVLCLRCQSLLYLRLFKLKKESALKYSKTLTEHLKNSYNNSQAPSPGMGSKPVGMPSPVSPKLSPGNSGNYSSGTANPSGSGSSVMIPQRIHQMAASYVQVTSNFLYATEIWDQAEQLSKEQKEFFAELDKAMGPLVFNSSIMTDLVRYTRQGLHWLRLDAK", "length": 1166, "header": "tr|A0A8V0YLL1-1|A0A8V0YLL1_CHICK Computationally mapped isoform of ALF transcription elongation factor 4 OS=Gallus gallus OX=9031 GN=AFF4 PE=3 SV=1 CANONICAL=A0A8V0YL30-1" }, "locus": { "chromosome": "13", "start_pos": 16715611, "end_pos": 16688976, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032971.1", "url": "https://www.ensembl.org/id/ENSGALT00010032971.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019496.1", "url": "https://www.ensembl.org/id/ENSGALP00010019496.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 413, "start_aa": "Thr", "end_pos": 413, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr413", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 535, "start_aa": "Thr", "end_pos": 535, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr535", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:416337", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416337", "resource": "KEGG Pathway" }, { "id": "R-GGA-112382", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-112382", "resource": "Reactome", "description": "Formation of RNA Pol II elongation complex" }, { "id": "R-GGA-674695", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-674695", "resource": "Reactome", "description": "RNA Polymerase II Pre-transcription Events" }, { "id": "R-GGA-75955", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-75955", "resource": "Reactome", "description": "RNA Polymerase II Transcription Elongation" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6GGV9-1", "protein_name": "ALF transcription elongation factor 4", "gene_name": "Aff4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEISNMNREDRNVLRMKERERRNQEIQQGEDAFPPSSPLFAEPYKVTSKEDKLSSRIQSMLGNYDEMKDYIGDRSIPKLVAIPKPAVPTTTDEKANPNFFEQRHGGSHQSSKWTPVGPAPSTSQSQKRSSGLQSGHSSQRSSAGGSGASGSGQRHDRDSYSSSRKKGQHGSEHSKSRSSSPGKPQAVSSLSSSHSRSHGNDHHSKEHQRSKSPRDPDANWDSPSRVPFSSGQHSSQSFPPSLMSKSSSMLQKPTAYVRPMDGQESVEPKLSSEHYSSQSHGSNMTELKPSSKAHLTKLKIPSRPLDASVSGDVSCVDEILKEMTHSWPPPLTAIHTPCKTEPSKFPFPTKESQQSNFGSGEQKRYSTSAKTSNGHQSKSMLKDDLKLSSSEDSDGEQDCDKTMPRSTPGSNSEPSHHNSEGADNSRDDSSSHSGSESSSGSDSESESSSSDSEANEPSQSASPEPEPPPTNKWQLDNWLNKVNPHKVSPASSVDSNIPSSQAYKKEGREQGTASNYTDPGGAKEASSATPGRDSKTIQKGSESGRGRQKSPAQSDSTTQRRTVGKKQPKKTEKSAAEEPRGGLKIESETPVDMATSMPSSRHKAATKGSRKPNIKKESKSSPRPTAEKKKYKSASKSSQKSREIIETDSSSSDSDERESLPPSSQTPKYPESNRTPVKPSSAEEDDSFFRQRMFSPMEEKELLSPLSDPDDRYPLIVKIDLNLLTRIPGKPYKETEPPKGEKKNVPEKHSREVQKQASEKASNKGKRKHKNDDDNRASESKKPKTEDKNSSAHKPSSSKESSKQSSTKEKDLLPSPAGPVPSKDSKTEHGSRKRTVSQSSSLKSSSTSNKENSGSSKSTSSTAKQKKTEGKVSSSSKEAKEKAPNSSSNCPPSTPTPDSSKPRRTKLAFDDRNYSADHYLQEAKKLKHNADALSDRFEKAVYYLDAVVSFIECGNALEKNAQESKSPFPMYSDTVELIKYTMKLKNYLAPDATAADKRLTVLCLRCQSLLYLRLFKLKKENALKYSKTLTEHLKNSYSNSQAPSPGLGSKAVGMPSPVSPKLSPGNSGSYSSGGSSASASGSSVTIPQKIHQMAASYVQVTSNFLYATEIWDQAEQLSKEQKEFFAELDKVMGPLIFNASIMTDLARYTRQGLHWLRQDAKLIS", "length": 1164 }, "evidence": [ { "id": "A0A8V0YL30", "url": "https://omabrowser.org/oma/group/A0A8V0YL30/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0AAA9TGC5-1", "protein_name": "ALF transcription elongation factor 4", "gene_name": "AFF4", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MNREDRNVLRMKERERRNQEIQQGDDAFPPSSPLFAEPYKVTSKEDKLSSRIQSMLGNYDEMKDFIGDRSIPKLVAIPKPTVPPTADEKSNPNFFEQRHGSSHQSSKWTPVGPAPSTSQSQKRSSGLQSGHSSQRASAGASGGTNSSGQRHDRDSYSSGGSSSRKKGQHGSEHSKSRSSSPGKPQAVSSLSSSHSRSHGNDHHSKEHQRSKSPRDPDANWDSPSRVPFSSGQHSNQSFPPSLMSKSSSMLQKPTAYVRPMDGQESMEPKLSSEHYSSQSHGNSMTELKPSSKAHLTKLKIPSQPLDASASGDVSCVDEILKESQQSSFGPGEQKRYNPSSKTSNAHQSKSMLKDDLKLSSSEDSDGEQDCDKTMPRSTPGSNSEPSHHNSEGADNSRDDSSSHSGSESSSGSDSESESSSSDSEANEPSQSASPEPEPPPTNKWQLDNWLNKVNPHKVSPASSVDSNIPSSQGYKKEGREQGTGNSYTDPGGPKETSSATPGRDSKTVQKGSESGRGRQKSPAQSDSTAQRRTVGKKQPKKTEKAAAEEPRGGLKIESETPVDMATSMPSSRHKAATKGSRKPNIKKESKSSPRPSAEKKKYKSTSKSSQKSREIIETDTSSSDSDESESLPPSSQTPKYPESNRTPVKPSSVEEEDSFFRQRMFSPMEEKELLSPLSEPDDRYPLIVKIDLNLLTRIPGKPYKETEPPKGEKKNVPEKHTREAQKQASEKVSNKGKRKHKNEDDNRANESKKPKTEDKNMAGHKPSSNKESSKQSASKEKDLLPSPAGPVPSKDPKTEHGSRKRTVSQSSSLKSSNNSNKENSASSKNSSSASKQKRTEGKTSSSSKEVKEKAPNSSSNCPPSAPTPDASKPRRTKLAFDDRNYSADHYLQEAKKLKHNADALSDRFEKAVYYLDAVVSFIECGNALEKNAQESKSPFLMYSETVELIKYTMKLKNYLAPDATAADKRLTVLCLRCQSLLYLRLFKLKKETALKYSKTLTEHLKNSYNNSQAPSPGLGSKAVGMPSPVSPKLSPGNSGNYSSGASSASASGSSVTIPQRIHHMAASYVQVTSNFLYATEIWDQAEQLSKEQKEFFAELDKVMGPLIFNASIMTDLVRYTRQGLHWLRQDAKLIS", "length": 1135 }, "evidence": [ { "id": "A0A8V0YL30", "url": "https://omabrowser.org/oma/group/A0A8V0YL30/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q9ESC8-1", "protein_name": "AF4/FMR2 family member 4", "gene_name": "Aff4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNREDRNVLRMKERERRNQEIQQGEDAFPPSSPLFAEPYKVTSKEDKLSSRIQSMLGNYDEMKDYIGDRSIPKLVAIPKPAVPTTTDEKANPNFFEQRHGGSHQSSKWTPVGPAPSTSQSQKRSSALQSGHSSQRSGAGGSGASSSGQRHDRDSYSSSRKKGQHGSEHSKSRSSSPGKPQAVSSLSSSHSRSHGNDHHSKEHQRSKSPRDPDANWDSPSRGPFSSGQHSSQSFPPSLMSKSSSMLQKPTAYVRPMDGQESVEPKLSSEHYSSQSHGNSMTELKPSSKAHLTKLKIPSRPLDASVSGDVSCVDEILKEMTHSWPPPLTAIHTPCKTEPSKFPFPTKESQQSNFGPGEQKRYSTAKTSNGHQSKSMLKDDLKLSSSEDSDGEQDCDKTMPRSTPGSNSEPSHHNSEGADNSRDDSSSHSGSESSSGSDSESESSSSDSEANEPSQSASPEPEPPPTNKWQLDNWLNKVNPHKVSPASSVDSNIPSSQAYKKEGREQGTASNYTDPGGTKETSSATPGRDSKTIQKGSESGRGRQKSPAQSDSTTQRRTVGKKQPKKPEKSAAEEPRGGLKIESETPVDMAASMPSSRHKAATKGSRKPNIKKESKSSPRPTAEKKKYKSASKPSQKSREIIETDTSSSDSDGSESLPPSSQTPKYPESNRTPVKPSSVEEEDSFFRQRMFSPMEEKELLSPLSEPDDRYPLIVKIDLNLLTRIPGKPYKETEPPKGEKKNVPEKHSREVQKQASEKASNKGKRKHKNDDDTRASESKKPKTEDKNSSGHKPSSSRESSKQSSTKEKDLLPSPAGPILSKDSKTEHGSRKRTVSQSSSLKSSGTSSKENSGSSSKSSSSSTAKQKKTEGKGPSSSKEAKEKAPNSSSNCPPSTPTSESSKPRRTKLAFDDRNYSADHYLQEAKKLKHNADALSDRFEKAVYYLDAVVSFIECGNALEKNAQESKSPFPMYSDTVELIKYTMKLKNYLAPDATAADKRLTVLCLRCQSLLYLRLFKLKKENALKYSKTLTEHLKNSYSNSQAPSPGLGSKAVGMPSPVSPKLSPGNSGSYSSGGSSASASGSSVTIPQKIHQMAASYVQVTSNFLYATEIWDQAEQLSKEQKEFFAELDKVMGPLIFNASIMTDLARYTRQGLHWLRQDAKLIS", "length": 1160 }, "evidence": [ { "id": "A0A8V0YL30", "url": "https://omabrowser.org/oma/group/A0A8V0YL30/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9UHB7-1", "protein_name": "AF4/FMR2 family member 4", "gene_name": "AFF4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": 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"UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL35/entry#names_and_taxonomy" } ] }, { "name": "insulin receptor substrate 4", "type": "synonym", "evidence": [ { "id": "XP_003641132", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003641132" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052535.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_003641132.3. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003641132", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003641132" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YL35", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL35" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "IRS4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL35", "locus": { "chromosome": "4", "start_pos": 13856522, "end_pos": 13834941, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010015557", "url": "https://www.ensembl.org/id/ENSGALG00010015557" } ] } } ], "crossref": [ { "id": "A0A8V0YL35", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YL35", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd01204", 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"MASGMNGPGGGGGGAGAAVRGGEEEPGARHAGGGAVPQQREPGAAGEGEPAAGDGGRCPSPQPHHLLLLLRRSPSASLCPPAEGPAGRAALGRGGQPPPAGRAAPPASSSGGDDVRKCGYLRKQKHGHKRYFVLRADSPLAPARLEYYDSEKKFKSSLRAGGGGAAPVCCPPPKRVIPLYQCFTVSRRADAKHKHIIALYTKDEYFAMLAENEAEQEAWYEAISELMSQTKRGCLEQEDQAEQQVDEDDEHYGTSLRPGTVFKEVWQVNVKPKGLGQTKNLTGVYRLCLSSKAIHLVKLNSEVPSVHLQLMNIRRCGHSENFFFIEVGRSASIGPGELWMQVDDSVVAQNMHETFLETMKALKAFAEFRPRSKSQSSGGGGGTNPISFITTRRHLGNLPPSQTGLQRRSRTESVVGGTPPTTKSSNSYRFRTSSEGEGTMTRPFRSVTGSLIHLNTARMNLGRQEGSGRYVRAAFSSSYHTRSASLPVSHFPSTTSPISVSSSSGHGSASDMLTRPSSSSVCGSPSDGGFISSDEYGSSPGDFRYFRVRSNTPDSLGNTPPIREENCLSEYMSMSKQQADDNSRDDYMEAEKCFRKRTYSLTKPTSVAVQQKTTQTTALLDEDSVGNHGRLLYSETSKLKGNHELEYSDSNLDSICNQSRSKARDDGYMPMMPGVASSLSSNSDYLPMTPKSMSVPKQINNSWSPSQVDSRGYMMMFPKASSSPVRSPLTGFISKGSNEKIVNNEYMDMSPGNSAPKHPGDSNYIHTSSASKGFSSYFSLPRSFKALTGQNGDHSEYVPMSSPGKLLYGGPENVKSTNSEVLSNGISKSPVAKGSDEGLVQNRATRPTRLPLGTRGSNTIPRMYDRTVPPEPASPGEYINIDFNEKASNTPYSLSAEGSPSSLGSSSDHRQSPLSDYMSVDLDVQSPKVAKELSNSLTDISIYASSSIPRNQQNPDYARLSFGTACVSAANNRTDDYTEMTFNMAATPPRPFAAESDDGVKMDSPSSIVNRLCIVDRYAGSSSFSVPSAEPPMGPKVIRADPQGRRRHSSETFSSAGTVTTSSSFFTDSSKRHSSASFDNVWLKPDESISDGQESKMSRDTSTGFQNGLNYIALNLCDDPISCEASTGTPTCHLQNGTSSLDSGAYVSIDFTRSDGLKCNAARKD", "length": 1165, "header": "tr|A0A8V0YL35-1|A0A8V0YL35_CHICK Isoform 1 of Insulin receptor substrate 4 OS=Gallus gallus OX=9031 GN=IRS4 PE=4 SV=1 CANONICAL=A0A8V0YL35-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YL35-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL35/entry#A0A8V0YL35-1", "sequence": { "sequence": "MASGMNGPGGGGGGAGAAVRGGEEEPGARHAGGGAVPQQREPGAAGEGEPAAGDGGRCPSPQPHHLLLLLRRSPSASLCPPAEGPAGRAALGRGGQPPPAGRAAPPASSSGGDDVRKCGYLRKQKHGHKRYFVLRADSPLAPARLEYYDSEKKFKSSLRAGGGGAAPVCCPPPKRVIPLYQCFTVSRRADAKHKHIIALYTKDEYFAMLAENEAEQEAWYEAISELMSQTKRGCLEQEDQAEQQVDEDDEHYGTSLRPGTVFKEVWQVNVKPKGLGQTKNLTGVYRLCLSSKAIHLVKLNSEVPSVHLQLMNIRRCGHSENFFFIEVGRSASIGPGELWMQVDDSVVAQNMHETFLETMKALKAFAEFRPRSKSQSSGGGGGTNPISFITTRRHLGNLPPSQTGLQRRSRTESVVGGTPPTTKSSNSYRFRTSSEGEGTMTRPFRSVTGSLIHLNTARMNLGRQEGSGRYVRAAFSSSYHTRSASLPVSHFPSTTSPISVSSSSGHGSASDMLTRPSSSSVCGSPSDGGFISSDEYGSSPGDFRYFRVRSNTPDSLGNTPPIREENCLSEYMSMSKQQADDNSRDDYMEAEKCFRKRTYSLTKPTSVAVQQKTTQTTALLDEDSVGNHGRLLYSETSKLKGNHELEYSDSNLDSICNQSRSKARDDGYMPMMPGVASSLSSNSDYLPMTPKSMSVPKQINNSWSPSQVDSRGYMMMFPKASSSPVRSPLTGFISKGSNEKIVNNEYMDMSPGNSAPKHPGDSNYIHTSSASKGFSSYFSLPRSFKALTGQNGDHSEYVPMSSPGKLLYGGPENVKSTNSEVLSNGISKSPVAKGSDEGLVQNRATRPTRLPLGTRGSNTIPRMYDRTVPPEPASPGEYINIDFNEKASNTPYSLSAEGSPSSLGSSSDHRQSPLSDYMSVDLDVQSPKVAKELSNSLTDISIYASSSIPRNQQNPDYARLSFGTACVSAANNRTDDYTEMTFNMAATPPRPFAAESDDGVKMDSPSSIVNRLCIVDRYAGSSSFSVPSAEPPMGPKVIRADPQGRRRHSSETFSSAGTVTTSSSFFTDSSKRHSSASFDNVWLKPDESISDGQESKMSRDTSTGFQNGLNYIALNLCDDPISCEASTGTPTCHLQNGTSSLDSGAYVSIDFTRSDGLKCNAARKD", "length": 1165, "header": "tr|A0A8V0YL35-1|A0A8V0YL35_CHICK Isoform 1 of Insulin receptor substrate 4 OS=Gallus gallus OX=9031 GN=IRS4 PE=4 SV=1 CANONICAL=A0A8V0YL35-1" }, "locus": { "chromosome": "4", "start_pos": 13854192, "end_pos": 13835140, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010037390.1", "url": "https://www.ensembl.org/id/ENSGALT00010037390.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021661.1", "url": "https://www.ensembl.org/id/ENSGALP00010021661.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 418, "start_aa": "Thr", "end_pos": 418, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr418", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:422347", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422347", "resource": "KEGG Pathway" }, { "id": "R-GGA-2428928", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2428928", "resource": "Reactome", "description": "IRS-related events triggered by IGF1R" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "insulin receptor binding", "id": "GO:0005158", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005158", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YL35", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL35" } ], "pmid": "" }, { "name": "phosphatidylinositol 3-kinase binding", "id": "GO:0043548", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043548", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YL35", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL35" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YL35", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL35" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YL35", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL35" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "insulin receptor signaling pathway", "id": "GO:0008286", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008286", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YL35", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL35" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1136, "end_pos": 1138, "annotation": "n_glycosylation_sequon" }, { "start_pos": 280, "end_pos": 282, "annotation": "n_glycosylation_sequon" }, { "start_pos": 657, "end_pos": 659, "annotation": "n_glycosylation_sequon" }, { "start_pos": 700, "end_pos": 702, "annotation": "n_glycosylation_sequon" }, { "start_pos": 972, "end_pos": 974, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YL35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL35" }, { "id": "PS51064", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51064" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "IRS-type PTB", "eco_id": "ECO_0000259", "start_pos": 262, "end_pos": 366, "start_aa": "Phe", "end_aa": "Ala", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0YL35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL35" }, { "id": "PS50003", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50003" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PH", "eco_id": "ECO_0000259", "start_pos": 114, "end_pos": 228, "start_aa": "Asp", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 418 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1136, "end_pos": 1138 }, { "start_pos": 280, "end_pos": 282 }, { "start_pos": 657, "end_pos": 659 }, { "start_pos": 700, "end_pos": 702 }, { "start_pos": 972, "end_pos": 974 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YL52-1", "uniprot_ac": "A0A8V0YL52", "uniprot_id": "A0A8V0YL52_CHICK", "mass": { "chemical_mass": 49817.0, "monoisotopic_mass": 49817.0 }, "refseq": { "ac": "XP_001231953", "name": "beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 7", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001231953" }, "gene_names": [ { "name": "GCNT7", "type": "recommended", "evidence": [ { "id": "A0A8V0YL52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL52" } ] }, { "name": "GCNT7", "type": "synonym", "evidence": [ { "id": "XP_001231953", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001231953" } ] } ], "protein_names": [ { "name": "Glucosaminyl (N-acetyl) transferase family member 7", "type": "synonym", "evidence": [ { "id": "A0A8V0YL52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL52/entry#names_and_taxonomy" } ] }, { "name": "beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 7", "type": "synonym", "evidence": [ { "id": "XP_001231953", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001231953" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052551.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_001231953.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_001231953", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001231953" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YL52", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL52" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "GCNT7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL52", "locus": { "chromosome": "20", "start_pos": 12325602, "end_pos": 12322300, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013235", "url": "https://www.ensembl.org/id/ENSGALG00010013235" } ] } } ], "crossref": [ { "id": "A0A8V0YL52", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YL52", "database": "AlphaFoldDB", "categories": [] }, { "id": "769120", "url": "https://www.ncbi.nlm.nih.gov/gene/769120", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003406", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003406", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:769120", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:769120", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "TCLERWH", "url": "https://omabrowser.org/oma/group/TCLERWH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YL52", "url": "https://www.orthodb.org/?gene=A0A8V0YL52", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR19297", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19297", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19297:SF178", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19297:SF178", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02485", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02485", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-913709", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-913709", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_001231953", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001231953", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YL52", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL52", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YL52-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL52-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNPLDVTKSGFLLCIAVCMFIYTFIYLKDTLSAEPDEQKCSTNRAECGFYPDELCSALFVGKTAALKIGSICQNTNRPAALSCVQTPCNCSVVLKALHFITRPLSAEEGNFSLAYIITIHKELEMFVKLLRAIYMPQNIYCIHVDEKSPTDYKAAVQNIVNCFENIFISSKRENVVYAGFSRLQADINCMRDLVHSKIQWNYVINLCGQDYPIKTNKDIIKYIKSKWNGKNMTPGVVQPLHMKHRTQVSYREYVHSGMSYVYPTKNAKTKPPYNLTIYFGSAYYILTKEFVEFTLTDVRAKDLLEWSRDTYSPDEHYWVTLNRLHDAPGATPNAEWEGNIRAIKWKDQEGTVHKGCKGHYIRDICVYGLGDLQWIIESPHLFANKFEPATYPLVTDCLERRHRLKVLHQAEVPIEDDWRFQKDNSFNMKLNV", "length": 432, "header": "tr|A0A8V0YL52-1|A0A8V0YL52_CHICK Isoform 1 of Glucosaminyl (N-acetyl) transferase family member 7 OS=Gallus gallus OX=9031 GN=GCNT7 PE=3 SV=1 CANONICAL=A0A8V0YL52-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YL52-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL52/entry#A0A8V0YL52-1", "sequence": { "sequence": "MNPLDVTKSGFLLCIAVCMFIYTFIYLKDTLSAEPDEQKCSTNRAECGFYPDELCSALFVGKTAALKIGSICQNTNRPAALSCVQTPCNCSVVLKALHFITRPLSAEEGNFSLAYIITIHKELEMFVKLLRAIYMPQNIYCIHVDEKSPTDYKAAVQNIVNCFENIFISSKRENVVYAGFSRLQADINCMRDLVHSKIQWNYVINLCGQDYPIKTNKDIIKYIKSKWNGKNMTPGVVQPLHMKHRTQVSYREYVHSGMSYVYPTKNAKTKPPYNLTIYFGSAYYILTKEFVEFTLTDVRAKDLLEWSRDTYSPDEHYWVTLNRLHDAPGATPNAEWEGNIRAIKWKDQEGTVHKGCKGHYIRDICVYGLGDLQWIIESPHLFANKFEPATYPLVTDCLERRHRLKVLHQAEVPIEDDWRFQKDNSFNMKLNV", "length": 432, "header": "tr|A0A8V0YL52-1|A0A8V0YL52_CHICK Isoform 1 of Glucosaminyl (N-acetyl) transferase family member 7 OS=Gallus gallus OX=9031 GN=GCNT7 PE=3 SV=1 CANONICAL=A0A8V0YL52-1" }, "locus": { "chromosome": "20", "start_pos": 12325245, "end_pos": 12322792, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031791.1", "url": "https://www.ensembl.org/id/ENSGALT00010031791.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018610.1", "url": "https://www.ensembl.org/id/ENSGALP00010018610.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:769120", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:769120", "resource": "KEGG Pathway" }, { "id": "R-GGA-913709", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-913709", "resource": "Reactome", "description": "O-linked glycosylation of mucins" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8M2BG25-1", "protein_name": "N-acetyllactosaminide beta-1,6-N-acetylglucosaminyl-transferase", "gene_name": "gcnt7", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MVQLENTKCSFLFCLGICTLICSAIYLKAKVASDPLPINDLTTLSPTPPPLPCPPSNTCDILPPATPGFKWQRKDCEKISYHIQPDTNCDLLLSQLHFITAPLSKEEEDYPLAFIITIHKELATFVRLLRAIYAPQNVYCIHIDQKASEKYKSSVRNLSRCFPNVFLSSVNVKVTYAGFSRLQADINCMKDLVESPIQWKKVINLCGQDYPIQTNLELVRYMQTPEWKDRNMTPGIKQPPSMRYRTAFQYVEVKNTHVAQTGRKKGPPPHNLKIYFGTAYYSLTRPFVEYVLDNPVAKDLLSWSKDSYSPDEHYWVTLNHIKEAPGSNVEGEWEGNVRAVKWSDQQGTAHQGCKGQYIRGICVYGIGDLPWLIEKESMFANKFEMASFPEALDCMELWHRHKVLQQATVPIQPSWHLTTEVEVVNRTLILTPGDCV", "length": 436 }, "evidence": [ { "id": "A0A8V0YL52", "url": "https://omabrowser.org/oma/group/A0A8V0YL52/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A5GFW8-1", "protein_name": "Probable beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 7", "gene_name": "GCNT7", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSQLRATKPGILVCAAIGIFVFLYLRNPTSEDPEEGPTHPAVVECGFYPDELCSALFEGKEAALQIAKFCKDPHGSEIVARLHRPGNCSRISRELHFITRPLSAEEGTFPLAYIVTIHKELALFVQLLRAIYLPQNVYCIHVDAKAPKKYKTAVQSLVNCFENIFISSKREKVAYTGFRRLQAEINCMKDLVHSKFQWSHVINLCGQDFPIKTNKDIIRYIRSKWNDKNITPGVIQPPSNKSKTSQTHREFTPEGNIYASPNERFRDDPPHNLTIYFGSASYVLTRKFVEFVLTDTRAKDMLRWSQDIHGPERHYWVTLNRLKDAPGSTPNAGWEGNVRAVKWRSEEGTVRDGCKGRYVQDSCVYGPGDLPWIIQSPSLFASQFDSAEPLVVTCLERWHRLRVLGQAEVPEEPHWHFQRESHLNRRLNP", "length": 429 }, "evidence": [ { "id": "A0A8V0YL52", "url": "https://omabrowser.org/oma/group/A0A8V0YL52/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "D3ZBX5-1", "protein_name": "Glucosaminyl (N-acetyl) transferase family member 7", "gene_name": "Gcnt7", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSRLWTTKAGLVACGMICAFIFLYLRSPGPEEADAEPTRPAVVECGFYPDELCSALFEGKKAAPQIAQFCRPPRNSEVLAHLSTPGNCSRMAQGLHFITRPLSAEEGNFSLAYVIHAPKELAMLVRLLRAIYAPQNVYCIHTDDKAPTKFKSAMQTFVGCFRNVFLSSKTQKVAHDNLRRLQAEIDCMRDLVRSPLQWRYVMNLGGQEFPIKTNKEIIHYIRTRWKGKNITPGVTPPSNTKPKTGQSPPKPSSNENSYTSPNTRFKPKPPRNLTIHSGSAYYALTRNFVEFVLTDPRAKDMLQWSKDILSPEQHYWVTLNRLKDAPGATAGAGWEGHIRATKQRTEAGDGHTGCTGHDAQDTCVYGLGDLPWLVQLPAFFATMEPSTDPLVVVCIERRHRLKALQQAKVPPEPHWQFPQESHFSSQAHD", "length": 429 }, "evidence": [ { "id": "A0A8V0YL52", "url": "https://omabrowser.org/oma/group/A0A8V0YL52/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q3V3K7-1", "protein_name": "Probable beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 7", "gene_name": "Gcnt7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSQLRTTKAGLVACGMICAFIFLYLRNPGPEEAEAEAEAEPTNPAVVECGFYPDELCSALFDGKKAAPQIAQFCKPPQNSEVPARLRTPGNCSRLARGLHFITRPLSAEEGNFSLAYVIHAPRELVMFVRLLRAIYAPQNVYCIHSDENAPKKFKSAMQTFVDCFGNIFLSSKTQKVAHDNLRRLQAEIDCMRDLVHSPFQWHYVMNLCGQEFPIKTNKEIIYDIRTRWKGKNITPGVTPPANSKPKTGQGPPKPSPDENSYTAPNTIFKQSPPHNLTISSGSAHYALTRKFVEFVLTDPRAKDMLQWSKDIQSPEKHYWVTLNRLKDAPGATPDAGWEGHIRATKWRTEAGDGRKGCTDHDAQDTCVYGLGDLPGLIRLPAFFATLEPSSDPLVGVCLERRHRLRALQQAEVPPEPHWQFPQQSHFNSQPHH", "length": 433 }, "evidence": [ { "id": "A0A8V0YL52", "url": "https://omabrowser.org/oma/group/A0A8V0YL52/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YL52", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL52" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "acetylglucosaminyltransferase activity", "id": "GO:0008375", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008375", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YL52", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL52" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 110, "end_pos": 112, "annotation": "n_glycosylation_sequon" }, { "start_pos": 231, "end_pos": 233, "annotation": "n_glycosylation_sequon" }, { "start_pos": 274, "end_pos": 276, "annotation": "n_glycosylation_sequon" }, { "start_pos": 89, "end_pos": 91, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 110, "end_pos": 112 }, { "start_pos": 231, "end_pos": 233 }, { "start_pos": 274, "end_pos": 276 }, { "start_pos": 89, "end_pos": 91 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YL61-1", "uniprot_ac": "A0A8V0YL61", "uniprot_id": "A0A8V0YL61_CHICK", "mass": { "chemical_mass": 25187.0, "monoisotopic_mass": 25187.0 }, "refseq": { "ac": "XP_025010728", "name": "single-pass membrane and coiled-coil domain-containing protein 3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025010728" }, "gene_names": [ { "name": "SMCO3", "type": "recommended", "evidence": [ { "id": "A0A8V0YL61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL61" } ] }, { "name": "SMCO3", "type": "synonym", "evidence": [ { "id": "XP_025010728", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025010728" } ] } ], "protein_names": [ { "name": "Single-pass membrane protein with coiled-coil domains 3", "type": "synonym", "evidence": [ { "id": "A0A8V0YL61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL61/entry#names_and_taxonomy" } ] }, { "name": "single-pass membrane and coiled-coil domain-containing protein 3", "type": "synonym", "evidence": [ { "id": "XP_025010728", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025010728" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_025010728.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_025010728", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025010728" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YL61", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL61" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SMCO3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL61", "locus": { "chromosome": "1", "start_pos": 48095484, "end_pos": 48090209, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012117", "url": "https://www.ensembl.org/id/ENSGALG00010012117" } ] } } ], "crossref": [ { "id": "769813", "url": "https://www.ncbi.nlm.nih.gov/gene/769813", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR027895", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027895", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040004", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040004", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:769813", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:769813", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MSTNFHA", "url": "https://omabrowser.org/oma/group/MSTNFHA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YL61", "url": "https://www.orthodb.org/?gene=A0A8V0YL61", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR35972", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR35972", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR35972:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR35972:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15047", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15047", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_025010728", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025010728", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YL61", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL61", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YL61-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL61-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MALSDLLYPENPRRRQELIHLHRELLDCMSMNFHATNELAGVLNAHLGCTITHIKMRESSTVKENCDIIIRAMHEIQCQVQKIDGDMKEKLEPVLYQKLYDIKEPELEKIAIAHKVFSIVLGEVTSTAGMVAVKLLSSNLITITVCKLISLLAQIGASVLGGISITILGLGMEMILHAILGAVERNQLLAAVRSYEEHLAEFKEASEKYQRAIHEVTSLVRHQVQ", "length": 225, "header": "tr|A0A8V0YL61-1|A0A8V0YL61_CHICK Isoform 1 of Single-pass membrane protein with coiled-coil domains 3 OS=Gallus gallus OX=9031 GN=SMCO3 PE=4 SV=1 CANONICAL=A0A8V0YL61-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YL61-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL61/entry#A0A8V0YL61-1", "sequence": { "sequence": "MALSDLLYPENPRRRQELIHLHRELLDCMSMNFHATNELAGVLNAHLGCTITHIKMRESSTVKENCDIIIRAMHEIQCQVQKIDGDMKEKLEPVLYQKLYDIKEPELEKIAIAHKVFSIVLGEVTSTAGMVAVKLLSSNLITITVCKLISLLAQIGASVLGGISITILGLGMEMILHAILGAVERNQLLAAVRSYEEHLAEFKEASEKYQRAIHEVTSLVRHQVQ", "length": 225, "header": "tr|A0A8V0YL61-1|A0A8V0YL61_CHICK Isoform 1 of Single-pass membrane protein with coiled-coil domains 3 OS=Gallus gallus OX=9031 GN=SMCO3 PE=4 SV=1 CANONICAL=A0A8V0YL61-1" }, "locus": { "chromosome": "1", "start_pos": 48094660, "end_pos": 48093986, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029049.1", "url": "https://www.ensembl.org/id/ENSGALT00010029049.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016808.1", "url": "https://www.ensembl.org/id/ENSGALP00010016808.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:769813", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:769813", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0AAA9S718-1", "protein_name": "NAD(P)(+)--arginine ADP-ribosyltransferase", "gene_name": "SMCO3", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MELRGQRNALHTNKCCPLTNHCRRILLANTAASAVRIWLLRGQLLLLLLCSGLQRPTIAVKIDFDLTPNSFDDQYRGCSQQVMEMLLQGDYFMEELESSKHYRKVWHQTHLNWLNQEKPLPGNMTITHALAVSVYLSDDRVHLDFSRAMASAAGSPQQYKHSFRFKYLHYFLTSAIQLLRKEIVSRKDSLCYEVQHELKGVYLRAPVGSIVRFGQFLSTSPAREQAQRFGNQTLFTMLTCLGAPVQDFSLKKEVLVPPYELFKVVNVSYHPRGNWLQLLSNGTQSTYNCQLLKASSRKCIPTPLVVASLSFLTSVIIFSKSGA", "length": 323 }, "evidence": [ { "id": "A0A8V0YL61", "url": "https://omabrowser.org/oma/group/A0A8V0YL61/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0ABK0L6I4-1", "protein_name": "Single-pass membrane protein with coiled-coil domains 3 like 1", "gene_name": "Smco3l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAQSDFLYPQNPRRRQEVNRLHQQLLDCLSDCFQVTNKLTGLLNAHLGCRLAFIEMRSDETIKRNCDLIIQAVTKIQKELQKVDEALKDKLEPTLYRKLRDIKERETEKIAIVQKVISVILGEATAAASAVAVKLVGSNVTTGIISKLASVLTHIGTSILGSIGVAVLSLGIDMVVQAILGAVERTQLQSAIQSYEKHLTEFKAASEKYHHAIAEVTDAVKRQLR", "length": 225 }, "evidence": [ { "id": "A0A8V0YL61", "url": "https://omabrowser.org/oma/group/A0A8V0YL61/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A2RU48-1", "protein_name": "Single-pass membrane and coiled-coil domain-containing protein 3", "gene_name": "SMCO3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAQSDFLYPENPKRREEVNRLHQQLLDCLSDSFDVTNKLTEVLNMHLGCRLASIEMKRDGTIKENCDLIIQAIMKIQKELQKVDEALKDKLEPTLYRKLQDIKEKETDKIAIVQKVISVILGEATSAASAVAVKLVGSNVTTGIINKLVTVLAQIGASLLGSIGVAVLGLGIDMIVRAILGAVEKTQLQAAIKSYEKHLVEFKSASEKYNHAITEVINTVKHQMK", "length": 225 }, "evidence": [ { "id": "A0A8V0YL61", "url": "https://omabrowser.org/oma/group/A0A8V0YL61/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "F1SQV4-1", "protein_name": "Single-pass membrane protein with coiled-coil domains 3", "gene_name": "SMCO3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAQSDFLYPENPRRRQEVNRLHQELLDCLSDSFQATNKLIGVLNMHLGCRLASIEMKRDGTIKENCDIIIQAMMKIQKELQKVDEALKDKLEPTLYRKLQDIKERETEKIAIVQKVISVILGEATSAASAVAVKLVGSNVTTGIINKLVTVLAQIGASLLGSIGVAVLGLGIDMIFRAILGAVEKTQLQAAIKSYEKHLVEFKSASEKYHHAITEVTNTVKHQMK", "length": 225 }, "evidence": [ { "id": "A0A8V0YL61", "url": "https://omabrowser.org/oma/group/A0A8V0YL61/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3H4P7-1", "protein_name": "Single-pass membrane and coiled-coil domain-containing protein 3", "gene_name": "Smco3", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAQSDFLYPENPRRRQEVNRLHQQLLDCLSDSFQVTNKLTGVLNTHLGCRLAFIEMKRDGTIKENCDIIIQAVVKIQKELQKVDEALKDKLEPTLYRKLQDIKERETEKMAIVQKVISVILGEATSAASAVAVKLLGSNVTTGIMNKLVTVLAHIGTSLLGSIGVAVLGLGIDIIFRAILGAVERSQLQAAIKSYEKHLVEFKAASERYHHAITEVTRAVTRQIR", "length": 225 }, "evidence": [ { "id": "A0A8V0YL61", "url": "https://omabrowser.org/oma/group/A0A8V0YL61/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q8BQM7-1", "protein_name": "Single-pass membrane and coiled-coil domain-containing protein 3", "gene_name": "Smco3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAQSDFLYPQNPRRRQEVNRLHQQLLDCLSDSFQVTNKLTGVLNTHLGCRLAFIEMKSDGTIKENCDIIIQAMTKIQKELQKIDEALKDQLEPTLYRKLQDIKERETEKIAIVQKVISVILGEATSAASAVAVKLVGSSVTTGIISKLVSVLAHIGTSLLGSIGVAVLSLGIDMIIQAILGAVERTQLQAAIKSYEKHLEEFKAASAKYHHAITEVATAVKRQLR", "length": 225 }, "evidence": [ { "id": "A0A8V0YL61", "url": "https://omabrowser.org/oma/group/A0A8V0YL61/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YLP6-1", "uniprot_ac": "A0A8V0YLP6", "uniprot_id": "A0A8V0YLP6_CHICK", "mass": { "chemical_mass": 33216.0, "monoisotopic_mass": 33216.0 }, "refseq": {}, "gene_names": [ { "name": "FAM3B", "type": "recommended", "evidence": [ { "id": "A0A8V0YLP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLP6" } ] } ], "protein_names": [ { "name": "FAM3 metabolism regulating signaling molecule B", "type": "synonym", "evidence": [ { "id": "A0A8V0YLP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLP6/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLP6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLP6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "FAM3B", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLP6", "locus": { "chromosome": "1", "start_pos": 108989296, "end_pos": 108973371, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013758", "url": "https://www.ensembl.org/id/ENSGALG00010013758" } ] } } ], "crossref": [ { "id": "A0A8V0YLP6", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YLP6", "database": "AlphaFoldDB", "categories": [] }, { "id": "418527", "url": "https://www.ncbi.nlm.nih.gov/gene/418527", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR039220", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039220", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039477", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039477", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "LIMVATH", "url": "https://omabrowser.org/oma/group/LIMVATH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YL67", "url": "https://www.orthodb.org/?gene=A0A8V0YL67", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YL74", "url": "https://www.orthodb.org/?gene=A0A8V0YL74", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YL85", "url": "https://www.orthodb.org/?gene=A0A8V0YL85", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YLN0", "url": "https://www.orthodb.org/?gene=A0A8V0YLN0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YLP1", "url": "https://www.orthodb.org/?gene=A0A8V0YLP1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YLP6", "url": "https://www.orthodb.org/?gene=A0A8V0YLP6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YLR2", "url": "https://www.orthodb.org/?gene=A0A8V0YLR2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YNJ1", "url": "https://www.orthodb.org/?gene=A0A8V0YNJ1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YTH1", "url": "https://www.orthodb.org/?gene=A0A8V0YTH1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14592", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14592", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15711", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15711", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YL67", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL67", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YL67-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL67-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YL74", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL74", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YL74-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL74-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YL85", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL85", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YL85-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL85-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLN0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLN0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLN0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLN0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLP1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLP1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLP1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLP1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLP6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLP6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLP6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLP6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLR2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLR2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLR2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLR2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YNJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNJ1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YNJ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNJ1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YTH1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTH1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YTH1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTH1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "PARRGCAVTAAGGERRREEEEEEQRGTATGRGRVVHPRPERCGRGGTVSSSPPAFLCLVPSVCSFTRLSAACDFVKLSGLLLASLFAWYLGYIFAAHVPQESLSTSIAYLQDIGKKPVLKAPLPKRQKCDHWSPCSPGSYAYRVLSGGGKEKLAKICFEDELLISEEKGNVGRGINIAIVNYETGELTSANFFDMWEGDHSEEMVAFIENAPQGSLLFMVTHDDGSARLKSNAKKLVEALGSKEIQNMKFRSSWVFIAAKGFKLPDDIEREKINHSDSKKNRYNGWPAEIQIEGCIPRNLM", "length": 301, "header": "tr|A0A8V0YLP6-1|A0A8V0YLP6_CHICK Isoform 1 of FAM3 metabolism regulating signaling molecule B OS=Gallus gallus OX=9031 GN=FAM3B PE=3 SV=1 CANONICAL=A0A8V0YLP6-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YL67-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLP6/entry#A0A8V0YL67-1", "sequence": { "sequence": "SIPVPSDVAEAALSAQFNLKLPDFVKLSGLLLASLFAWYLGYIFAAHVPQESLSTSIAYLQDIGKKPVLKAPLPKRQKCDHWSPCSPGSYAYRVLSGGGKEKLAKICFEDELLISEEKGNVGRGINIAIVNYETGELTSANFFDMWEGDHSEEMVAFIENAPQGSLLFMVTHDDGSARLKSNAKKLVEALGSKEIQNMKFRSSWVFIAAKGFKLPDDIEREKINHSDSKKNRYNGWPAEIQIEGCIPRNLM", "length": 251, "header": "tr|A0A8V0YL67-1|A0A8V0YLP6_CHICK Computationally mapped isoform of FAM3 metabolism regulating signaling molecule B OS=Gallus gallus OX=9031 GN=FAM3B PE=3 SV=1 CANONICAL=A0A8V0YLP6-1" }, "locus": { "chromosome": "1", "start_pos": 108987557, "end_pos": 108977918, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033024.1", "url": "https://www.ensembl.org/id/ENSGALT00010033024.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019525.1", "url": "https://www.ensembl.org/id/ENSGALP00010019525.1" } ] } }, { "isoform_ac": "A0A8V0YL74-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLP6/entry#A0A8V0YL74-1", "sequence": { "sequence": "AQPCFHFVKLSGLLLASLFAWYLGYIFAAHVPQESLSTSIAYLQDIGKKPVLKAPLPKRQKCDHWSPCSPGSYAYRVLSGGGKEKLAKICFEDELLISEEKGNVGRGINIAIVNYETGELTSANFFDMWEGDHSEEMVAFIENAPQGSLLFMVTHDDGSARLKSNAKKLVEALGSKEIQNMKFRSSWVFIAAKGFKLPDDIEREKINHSDSKKNRYNGWPAEIQIEGCIPRNLM", "length": 234, "header": "tr|A0A8V0YL74-1|A0A8V0YL74_CHICK Computationally mapped isoform of FAM3 metabolism regulating signaling molecule B OS=Gallus gallus OX=9031 GN=FAM3B PE=3 SV=1 CANONICAL=A0A8V0YLP6-1" }, "locus": { "chromosome": "1", "start_pos": 108987557, "end_pos": 108978569, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033034.1", "url": "https://www.ensembl.org/id/ENSGALT00010033034.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019530.1", "url": "https://www.ensembl.org/id/ENSGALP00010019530.1" } ] } }, { "isoform_ac": "A0A8V0YL85-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLP6/entry#A0A8V0YL85-1", "sequence": { "sequence": "MWQRRHYFVKLSGLLLASLFAWYLGYIFAAHVPQESLSTSIAYLQDIGKKPVLKAPLPKRQKCDHWSPCSPGSYAYRVLSGGGKEKLAKICFEDELLISEEKGNVGRGINIAIVNYETGELTSANFFDMWEGDHSEEMVAFIENAPQGSLLFMVTHDDGSARLKSNAKKLVEALGSKEIQNMKFRSSWVFIAAKGFKLPDDIEREKINHSDSKKNRYNGWPAEIQIEGYEVCLDHPSLLFDSPVVHKPPIRQIPQLKLCPVAFQRYPAILQTKN", "length": 274, "header": "tr|A0A8V0YL85-1|A0A8V0YL85_CHICK Computationally mapped isoform of FAM3 metabolism regulating signaling molecule B OS=Gallus gallus OX=9031 GN=FAM3B PE=3 SV=1 CANONICAL=A0A8V0YLP6-1" }, "locus": { "chromosome": "1", "start_pos": 108988405, "end_pos": 108977937, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033048.1", "url": "https://www.ensembl.org/id/ENSGALT00010033048.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019540.1", "url": "https://www.ensembl.org/id/ENSGALP00010019540.1" } ] } }, { "isoform_ac": "A0A8V0YLN0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLP6/entry#A0A8V0YLN0-1", "sequence": { "sequence": "CVIFTKDFVKLSGLLLASLFAWYLGYIFAAHVPQESLSTSIAYLQDIGKKPVLKAPLPKRQKCDHWSPCSPGSYAYRVLSGGGKEKLAKICFEDELLISEEKGNVGRGINIAIVNYETGELTSANFFDMWEGDHSEEMVAFIENAPQGSLLFMVTHDDGSARLKSNAKKLVEALGSKEIQNMKFRSSWVFIAAKGFKLPDDIEREKINHSDSKKNRYNGWPAEIQIEGCIPRNLM", "length": 235, "header": "tr|A0A8V0YLN0-1|A0A8V0YLN0_CHICK Computationally mapped isoform of FAM3 metabolism regulating signaling molecule B OS=Gallus gallus OX=9031 GN=FAM3B PE=3 SV=1 CANONICAL=A0A8V0YLP6-1" }, "locus": { "chromosome": "1", "start_pos": 108987557, "end_pos": 108980192, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033013.1", "url": "https://www.ensembl.org/id/ENSGALT00010033013.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019518.1", "url": "https://www.ensembl.org/id/ENSGALP00010019518.1" } ] } }, { "isoform_ac": "A0A8V0YLP1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLP6/entry#A0A8V0YLP1-1", "sequence": { "sequence": "MVWDFMHVCVGTQKICAVCVTSVSEEYPVDPADAFSVVPCWLLNPQRQSQKFIGNVLQHFSELHPWRRSRPDFVKLSGLLLASLFAWYLGYIFAAHVPQESLSTSIAYLQDIGKKPVLKAPLPKRQKCDHWSPCSPGSYAYRVLSGGGKEKLAKICFEDELLISEEKGNVGRGINIAIVNYETGELTSANFFDMWEGDHSEEMVAFIENAPQGSLLFMVTHDDGSARLKSNAKKLVEALGSKEIQNMKFRSSWVFIAAKGFKLPDDIEREKINHSDSKKNRYNGWPAEIQIEGCIPRNLM", "length": 300, "header": "tr|A0A8V0YLP1-1|A0A8V0YLP1_CHICK Computationally mapped isoform of FAM3 metabolism regulating signaling molecule B OS=Gallus gallus OX=9031 GN=FAM3B PE=3 SV=1 CANONICAL=A0A8V0YLP6-1" }, "locus": { "chromosome": "1", "start_pos": 108987557, "end_pos": 108978680, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033028.1", "url": "https://www.ensembl.org/id/ENSGALT00010033028.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019528.1", "url": "https://www.ensembl.org/id/ENSGALP00010019528.1" } ] } }, { "isoform_ac": "A0A8V0YLP6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLP6/entry#A0A8V0YLP6-1", "sequence": { "sequence": "PARRGCAVTAAGGERRREEEEEEQRGTATGRGRVVHPRPERCGRGGTVSSSPPAFLCLVPSVCSFTRLSAACDFVKLSGLLLASLFAWYLGYIFAAHVPQESLSTSIAYLQDIGKKPVLKAPLPKRQKCDHWSPCSPGSYAYRVLSGGGKEKLAKICFEDELLISEEKGNVGRGINIAIVNYETGELTSANFFDMWEGDHSEEMVAFIENAPQGSLLFMVTHDDGSARLKSNAKKLVEALGSKEIQNMKFRSSWVFIAAKGFKLPDDIEREKINHSDSKKNRYNGWPAEIQIEGCIPRNLM", "length": 301, "header": "tr|A0A8V0YLP6-1|A0A8V0YLP6_CHICK Isoform 1 of FAM3 metabolism regulating signaling molecule B OS=Gallus gallus OX=9031 GN=FAM3B PE=3 SV=1 CANONICAL=A0A8V0YLP6-1" }, "locus": { "chromosome": "1", "start_pos": 108987557, "end_pos": 108977815, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033039.1", "url": "https://www.ensembl.org/id/ENSGALT00010033039.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019533.1", "url": "https://www.ensembl.org/id/ENSGALP00010019533.1" } ] } }, { "isoform_ac": "A0A8V0YLR2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLP6/entry#A0A8V0YLR2-1", "sequence": { "sequence": "LLTCCCASAFWTTLSPDFVKLSGLLLASLFAWYLGYIFAAHVPQESLSTSIAYLQDIGKKPVLKAPLPKRQKCDHWSPCSPGSYAYRVLSGGGKEKLAKICFEDELLISEEKGNVGRGINIAIVNYETGELTSANFFDMWEGDHSEEMVAFIENAPQGSLLFMVTHDDGSARLKSNAKKLVEALGSKEIQNMKFRSSWVFIAAKGFKLPDDIEREKINHSDSKKNRYNGWPAEIQIEGCIPRNLM", "length": 245, "header": "tr|A0A8V0YLR2-1|A0A8V0YLR2_CHICK Computationally mapped isoform of FAM3 metabolism regulating signaling molecule B OS=Gallus gallus OX=9031 GN=FAM3B PE=3 SV=1 CANONICAL=A0A8V0YLP6-1" }, "locus": { "chromosome": "1", "start_pos": 108987557, "end_pos": 108976790, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033056.1", "url": "https://www.ensembl.org/id/ENSGALT00010033056.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019548.1", "url": "https://www.ensembl.org/id/ENSGALP00010019548.1" } ] } }, { "isoform_ac": "A0A8V0YNJ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLP6/entry#A0A8V0YNJ1-1", "sequence": { "sequence": "QQGPAAYDFVKLSGLLLASLFAWYLGYIFAAHVPQESLSTSIAYLQDIGKKPVLKAPLPKRQKCDHWSPCSPGSYAYRVLSGGGKEKLAKICFEDELLISEEKGNVGRGINIAIVNYETGELTSANFFDMWEGDHSEEMVAFIENAPQGSLLFMVTHDDGSARLKSNAKKLVEALGSKEIQNMKFRSSWVFIAAKGFKLPDDIEREKINHSDSKKNRYNGWPAEIQIEGCIPRNLM", "length": 236, "header": "tr|A0A8V0YNJ1-1|A0A8V0YNJ1_CHICK Computationally mapped isoform of FAM3 metabolism regulating signaling molecule B OS=Gallus gallus OX=9031 GN=FAM3B PE=3 SV=1 CANONICAL=A0A8V0YLP6-1" }, "locus": { "chromosome": "1", "start_pos": 108987557, "end_pos": 108973633, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033052.1", "url": "https://www.ensembl.org/id/ENSGALT00010033052.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019544.1", "url": "https://www.ensembl.org/id/ENSGALP00010019544.1" } ] } }, { "isoform_ac": "A0A8V0YTH1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLP6/entry#A0A8V0YTH1-1", "sequence": { "sequence": "MPIGFLVAVAKKSWLKSVLRMSYHSEEMVAFIENAPQGSLLFMVTHDDGSARLKSNAKKLVEALGSKEIQNMKFRSSWVFIAAKGFKLPDDIEREKINHSDSKKNRYNGWPAEIQIEGCIPRNLM", "length": 125, "header": "tr|A0A8V0YTH1-1|A0A8V0YTH1_CHICK Computationally mapped isoform of FAM3 metabolism regulating signaling molecule B OS=Gallus gallus OX=9031 GN=FAM3B PE=3 SV=1 CANONICAL=A0A8V0YLP6-1" }, "locus": { "chromosome": "1", "start_pos": 108987557, "end_pos": 108981998, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033019.1", "url": "https://www.ensembl.org/id/ENSGALT00010033019.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019522.1", "url": "https://www.ensembl.org/id/ENSGALP00010019522.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 9, "start_aa": "Thr", "end_pos": 9, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr9", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLP6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLP6" } ], "pmid": "" }, { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLP6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLP6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "carbohydrate binding", "id": "GO:0030246", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030246", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLP6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLP6" } ], "pmid": "" }, { "name": "cytokine activity", "id": "GO:0005125", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005125", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLP6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLP6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLP6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLP6" } ], "pmid": "" }, { "name": "insulin secretion", "id": "GO:0030073", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030073", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLP6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLP6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 274, "end_pos": 276, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YLP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLP6" }, { "id": "PF15711", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15711" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "ILEI/PANDER", "eco_id": "ECO_0000259", "start_pos": 173, "end_pos": 261, "start_aa": "Arg", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 9 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 274, "end_pos": 276 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YL87-1", "uniprot_ac": "A0A8V0YL87", "uniprot_id": "A0A8V0YL87_CHICK", "mass": { "chemical_mass": 46435.0, "monoisotopic_mass": 46435.0 }, "refseq": {}, "gene_names": [ { "name": "SDCBP2", "type": "recommended", "evidence": [ { "id": "A0A8V0YL87", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL87" } ] } ], "protein_names": [ { "name": "Syndecan binding protein 2", "type": "synonym", "evidence": [ { "id": "A0A8V0YL87", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL87/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YL87", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL87" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SDCBP2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL87", "locus": { "chromosome": "20", "start_pos": 10177952, "end_pos": 10172263, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013596", "url": "https://www.ensembl.org/id/ENSGALG00010013596" } ] } } ], "crossref": [ { "id": "A0A8V0YL87", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YL87", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd06721", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06721", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd06794", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06794", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001478", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001478", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036034", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036034", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051230", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051230", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YL87", "url": "https://www.orthodb.org/?gene=A0A8V0YL87", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YN36", "url": "https://www.orthodb.org/?gene=A0A8V0YN36", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YT32", "url": "https://www.orthodb.org/?gene=A0A8V0YT32", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12345", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12345", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12345:SF13", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12345:SF13", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00595", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00595", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YL87", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL87", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YL87-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL87-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YN36", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN36", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YN36-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN36-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YT32", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YT32", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YT32-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YT32-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MATLYPSLEDMKGHQVLQAQAAAGIGTPPTTVLTEKPKLPEKPKVTSSTVPSAPPALYPNLAELEDYMGLALSSEEIQKNLFPDSSTALTPVGSVPGQLVAPLSGNSAGLRRAEIKPGVREIHLCKDERGKTGLQLKNVDQGIFVQLVKANSPAALVGLRFGDQILQIDGKNCAGWSSDKAQRALKKASPEKIVMVVRDRPFQRTVTVHKDSTGHVGVVVKKGKIVSLAKDSSAARNGLLTHHYICEVNGQNVIGMKAVTRTDEVVHGPLHPRPLMPSLLFQHLGADAGVGAPMAKPGRGEGAQRKRWRYSAPPLSPPKRTHESYWCDTTPRPPALSTQTRAGERAPAPSASPCPHVPPPCPPYPPQGRRQRPSPAKQTQTQRRLLHPPQYRTAETREERRGEVYSFVGLFFFFFFFFLFFHFCI", "length": 425, "header": "tr|A0A8V0YL87-1|A0A8V0YL87_CHICK Isoform 1 of Syndecan binding protein 2 OS=Gallus gallus OX=9031 GN=SDCBP2 PE=1 SV=1 CANONICAL=A0A8V0YL87-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YL87-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL87/entry#A0A8V0YL87-1", "sequence": { "sequence": "MATLYPSLEDMKGHQVLQAQAAAGIGTPPTTVLTEKPKLPEKPKVTSSTVPSAPPALYPNLAELEDYMGLALSSEEIQKNLFPDSSTALTPVGSVPGQLVAPLSGNSAGLRRAEIKPGVREIHLCKDERGKTGLQLKNVDQGIFVQLVKANSPAALVGLRFGDQILQIDGKNCAGWSSDKAQRALKKASPEKIVMVVRDRPFQRTVTVHKDSTGHVGVVVKKGKIVSLAKDSSAARNGLLTHHYICEVNGQNVIGMKAVTRTDEVVHGPLHPRPLMPSLLFQHLGADAGVGAPMAKPGRGEGAQRKRWRYSAPPLSPPKRTHESYWCDTTPRPPALSTQTRAGERAPAPSASPCPHVPPPCPPYPPQGRRQRPSPAKQTQTQRRLLHPPQYRTAETREERRGEVYSFVGLFFFFFFFFLFFHFCI", "length": 425, "header": "tr|A0A8V0YL87-1|A0A8V0YL87_CHICK Isoform 1 of Syndecan binding protein 2 OS=Gallus gallus OX=9031 GN=SDCBP2 PE=1 SV=1 CANONICAL=A0A8V0YL87-1" }, "locus": { "chromosome": "20", "start_pos": 10177776, "end_pos": 10175446, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032665.1", "url": "https://www.ensembl.org/id/ENSGALT00010032665.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019358.1", "url": "https://www.ensembl.org/id/ENSGALP00010019358.1" } ] } }, { "isoform_ac": "A0A8V0YN36-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL87/entry#A0A8V0YN36-1", "sequence": { "sequence": "MPHLARGGGCQLRPLGPSPGMGSAIKAQGGVKGSAQEPEISAGSATAMATLYPSLEDMKGHQVLQAQAAAGIGTPPTTVLTEKPKLPEKPKVTSSTVPSAPPALYPNLAELEDYMGLALSSEEIQKNLFPDSSTALTPVGSVPGQLVAPLSGNSAGLRRAEIKPGVREIHLCKDERGKTGLQLKNVDQGIFVQLVKANSPAALVGLRFGDQILQIDGKNCAGWSSDKAQRALKKASPEKIVMVVRDRPFQRTVTVHKDSTGHVGVVVKKGKIVSLAKDSSAARNGLLTHHYICEVNGQNVIGMKDKQLMEVLTGAGNVITLTIIPAVIYEHMVKRLSPGQMKSSMDHSIPDL", "length": 352, "header": "tr|A0A8V0YN36-1|A0A8V0YN36_CHICK Computationally mapped isoform of Syndecan binding protein 2 OS=Gallus gallus OX=9031 GN=SDCBP2 PE=1 SV=1 CANONICAL=A0A8V0YL87-1" }, "locus": { "chromosome": "20", "start_pos": 10177324, "end_pos": 10174721, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032675.1", "url": "https://www.ensembl.org/id/ENSGALT00010032675.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019364.1", "url": "https://www.ensembl.org/id/ENSGALP00010019364.1" } ] } }, { "isoform_ac": "A0A8V0YT32-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL87/entry#A0A8V0YT32-1", "sequence": { "sequence": "MHRFPRRCPSPARCRGSATAMATLYPSLEDMKGHQVLQAQAAAGIGTPPTTVLTEKPKLPEKPKVTSSTVPSAPPALYPNLAELEDYMGLALSSEEIQKNLFPDSSTALTPVGSVPGQLVAPLSGNSAGLRRAEIKPGVREIHLCKDERGKTGLQLKNVDQGIFVQLVKANSPAALVGLRFGDQILQIDGKNCAGWSSDKAQRALKKASPEKIVMVVRDRPFQRTVTVHKDSTGHVGVVVKKGKIVSLAKDSSAARNGLLTHHYICEVNGQNVIGMKDKQLMEVLTGAGNVITLTIIPAVIYEHMVKRLSPGQMKSSMDHSIPDL", "length": 325, "header": "tr|A0A8V0YT32-1|A0A8V0YT32_CHICK Computationally mapped isoform of Syndecan binding protein 2 OS=Gallus gallus OX=9031 GN=SDCBP2 PE=1 SV=1 CANONICAL=A0A8V0YL87-1" }, "locus": { "chromosome": "20", "start_pos": 10177324, "end_pos": 10172462, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032681.1", "url": "https://www.ensembl.org/id/ENSGALT00010032681.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019367.1", "url": "https://www.ensembl.org/id/ENSGALP00010019367.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "phosphatidylinositol-4,5-bisphosphate binding", "id": "GO:0005546", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005546", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YL87", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL87" } ], "pmid": "" }, { "name": "protein homodimerization activity", "id": "GO:0042803", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042803", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YL87", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL87" } ], "pmid": "" }, { "name": "protein heterodimerization activity", "id": "GO:0046982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046982", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YL87", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL87" } ], "pmid": "" }, { "name": "lipid binding", "id": "GO:0008289", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008289", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YL87", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL87" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YL87", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL87" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YL87", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL87" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YL87", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL87" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YL87", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL87" } ], "pmid": "" }, { "name": "nuclear speck", "id": "GO:0016607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016607", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YL87", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL87" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YL87", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL87" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "cell population proliferation", "id": "GO:0008283", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008283", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YL87", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL87" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YL87", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL87" }, { "id": "PS50106", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50106" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PDZ", "eco_id": "ECO_0000259", "start_pos": 121, "end_pos": 200, "start_aa": "Glu", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YL91-1", "uniprot_ac": "A0A8V0YL91", "uniprot_id": "A0A8V0YL91_CHICK", "mass": { "chemical_mass": 171905.0, "monoisotopic_mass": 171905.0 }, "refseq": {}, "gene_names": [ { "name": "GEMIN5", "type": "recommended", "evidence": [ { "id": "A0A8V0YL91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL91" } ] } ], "protein_names": [ { "name": "Gem nuclear organelle associated protein 5", "type": "synonym", "evidence": [ { "id": "A0A8V0YL91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL91/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YL91", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL91" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "GEMIN5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL91", "locus": { "chromosome": "13", "start_pos": 11642490, "end_pos": 11619198, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010015580", "url": "https://www.ensembl.org/id/ENSGALG00010015580" } ] } } ], "crossref": [ { "id": "416254", "url": "https://www.ncbi.nlm.nih.gov/gene/416254", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001680", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001680", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011043", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011043", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019775", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019775", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020472", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020472", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036322", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036322", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052640", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052640", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056420", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056420", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056421", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056421", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056424", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056424", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056432", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056432", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:416254", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416254", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YWFNRND", "url": "https://omabrowser.org/oma/group/YWFNRND/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YL91", "url": "https://www.orthodb.org/?gene=A0A8V0YL91", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YZD1", "url": "https://www.orthodb.org/?gene=A0A8V0YZD1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46362", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46362", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46362:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46362:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00400", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00400", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23770", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23770", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23774", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23774", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23775", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23775", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23777", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23777", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-191859", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-191859", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YL91", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL91", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YL91-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL91-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YZD1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZD1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YZD1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZD1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAAVRVLPASPNWYCSRCSDTSGDGRLFGFAARHRISVLDVSTATPTFHGELIGHTERIAAFAFCPHREHGALCASGSDDGSVRLWDAAGLVLRGEHGLHQNAITALHWSPLVKDLIVSGDEKGVIVCYWHSRSDSQQFFPEPRTIFCLTCSPHHENLVAVGYKDGMVVIIDISRKKEVLHRLRGHDDEIHCLAWCPVPGEGRLPAWQDELQEESDVPNGELKQDTAMKKSCYLASGSKDQTIRIWSCTRGRSVMTLKLPPTKRRGGAVDPAVKERIWLTVHWPCGRPTEIVSSSFGGELLHWDLTQPGKRKWTLLGSSEGQNHSRIVFNLCPLKHQDKELLLSISMDRDVKCWDLSTLDCSWTMPSLGGFVYSLAFSPVDPGCLAIGVGDSMIRVWNTLSMSNMFDVKTYWQSIKSKVTALAWHPTKEGCLAFGTDDGKVGIFDTLSSSAKNKPPQISSTYHKRTVYTLAWGPPTPPLSSGEEGEHPSVTLYSCAGEGIVFQHNPWKLSGEANDINKTIRDTNSIKHKLPARTEISWKPDGKLLALGNEDGSIEIFQAPNLKLLCTIQQHHKLINAIRWHHEHGSDPELSYLIASGSVNAIIYVHNLKSVIESTSESPLTITEPFRTLAGHTSKVTSLSWSPHHEGRLVSACYDGTAQVWDVMKEEPLCNYRGHQGRLLCVQWSPVDSDSIYTGADDFSVHKWLISKQEHTRPPQGKKSIELEKKRSIQPKVKAKKKKKPVGRSPAKQDQSDAVNGDESMKDTLLEENGVSDHEGEKEAQETELPDKDSIAVSKDTSLSAYDYSSLSSSKPFVTQKATPVKKDPPKEKPAPDASLKKRKPRSLLPFSTSMDHRSKDELHQDCLRLATCLKTKDHNEDVSPDLQNRIHLGLFTDRASLHNMIDVEGKYHLENGHPELFQQLMLWKGDMKGVLQAAAERGELTDQLVAMSPMVGYQAWVWTVEAFAKQLCFQEQYVKAASHLLSIHKVYEAVELLKVNNFYREAIVIAKARLRPEDPILKDLYTSWAALLEKDGHYSMAAKCYLGASSPYDAVKVMAKKGDAASLKTAAELALISGEEELSASLSFRCAQEMLLSRNWVGAQEVLQQQKTLFGQRLVFCLNELLCKCLSERNPCNRRSPVPPCYHSWELKRDASFFDMVIEVWQKVLGMDTTEKATCAWEQLHSIEHPPSTSNTHPKQVLFYISHDLTLAALSYQAAAWDEVVKSILGAVARSYDAGNFTLMQEICSIFLPEGCENLRDKLDSTNSQSMDACRSLEGFVACGLLYDLWWNPPKDPPAIQKACLDPALCPTEQTVLEQSCIPDHSSPEETPDQTAVETDENLNSTTEFNRCKTESDSKTNSVSLADRQSKLNGCKVLLSEAIAALQSTQRDIAEVQKILADMIHQHQQQRNNLQESTNGSIHENNVQQSSENELDEPLSDSSQIKRKDEVKETVTLPELTKRLMEAKQKLAEFPDSLKVFPFPDVLECCLVLLHIGAQCPPELHEQALDLLRKHEPTTDDEHMDFCISKDKHTSALEGGITP", "length": 1541, "header": "tr|A0A8V0YL91-1|A0A8V0YL91_CHICK Isoform 1 of Gem nuclear organelle associated protein 5 OS=Gallus gallus OX=9031 GN=GEMIN5 PE=1 SV=1 CANONICAL=A0A8V0YL91-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YL91-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL91/entry#A0A8V0YL91-1", "sequence": { "sequence": "MAAAVRVLPASPNWYCSRCSDTSGDGRLFGFAARHRISVLDVSTATPTFHGELIGHTERIAAFAFCPHREHGALCASGSDDGSVRLWDAAGLVLRGEHGLHQNAITALHWSPLVKDLIVSGDEKGVIVCYWHSRSDSQQFFPEPRTIFCLTCSPHHENLVAVGYKDGMVVIIDISRKKEVLHRLRGHDDEIHCLAWCPVPGEGRLPAWQDELQEESDVPNGELKQDTAMKKSCYLASGSKDQTIRIWSCTRGRSVMTLKLPPTKRRGGAVDPAVKERIWLTVHWPCGRPTEIVSSSFGGELLHWDLTQPGKRKWTLLGSSEGQNHSRIVFNLCPLKHQDKELLLSISMDRDVKCWDLSTLDCSWTMPSLGGFVYSLAFSPVDPGCLAIGVGDSMIRVWNTLSMSNMFDVKTYWQSIKSKVTALAWHPTKEGCLAFGTDDGKVGIFDTLSSSAKNKPPQISSTYHKRTVYTLAWGPPTPPLSSGEEGEHPSVTLYSCAGEGIVFQHNPWKLSGEANDINKTIRDTNSIKHKLPARTEISWKPDGKLLALGNEDGSIEIFQAPNLKLLCTIQQHHKLINAIRWHHEHGSDPELSYLIASGSVNAIIYVHNLKSVIESTSESPLTITEPFRTLAGHTSKVTSLSWSPHHEGRLVSACYDGTAQVWDVMKEEPLCNYRGHQGRLLCVQWSPVDSDSIYTGADDFSVHKWLISKQEHTRPPQGKKSIELEKKRSIQPKVKAKKKKKPVGRSPAKQDQSDAVNGDESMKDTLLEENGVSDHEGEKEAQETELPDKDSIAVSKDTSLSAYDYSSLSSSKPFVTQKATPVKKDPPKEKPAPDASLKKRKPRSLLPFSTSMDHRSKDELHQDCLRLATCLKTKDHNEDVSPDLQNRIHLGLFTDRASLHNMIDVEGKYHLENGHPELFQQLMLWKGDMKGVLQAAAERGELTDQLVAMSPMVGYQAWVWTVEAFAKQLCFQEQYVKAASHLLSIHKVYEAVELLKVNNFYREAIVIAKARLRPEDPILKDLYTSWAALLEKDGHYSMAAKCYLGASSPYDAVKVMAKKGDAASLKTAAELALISGEEELSASLSFRCAQEMLLSRNWVGAQEVLQQQKTLFGQRLVFCLNELLCKCLSERNPCNRRSPVPPCYHSWELKRDASFFDMVIEVWQKVLGMDTTEKATCAWEQLHSIEHPPSTSNTHPKQVLFYISHDLTLAALSYQAAAWDEVVKSILGAVARSYDAGNFTLMQEICSIFLPEGCENLRDKLDSTNSQSMDACRSLEGFVACGLLYDLWWNPPKDPPAIQKACLDPALCPTEQTVLEQSCIPDHSSPEETPDQTAVETDENLNSTTEFNRCKTESDSKTNSVSLADRQSKLNGCKVLLSEAIAALQSTQRDIAEVQKILADMIHQHQQQRNNLQESTNGSIHENNVQQSSENELDEPLSDSSQIKRKDEVKETVTLPELTKRLMEAKQKLAEFPDSLKVFPFPDVLECCLVLLHIGAQCPPELHEQALDLLRKHEPTTDDEHMDFCISKDKHTSALEGGITP", "length": 1541, "header": "tr|A0A8V0YL91-1|A0A8V0YL91_CHICK Isoform 1 of Gem nuclear organelle associated protein 5 OS=Gallus gallus OX=9031 GN=GEMIN5 PE=1 SV=1 CANONICAL=A0A8V0YL91-1" }, "locus": { "chromosome": "13", "start_pos": 11642229, "end_pos": 11619226, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010037523.1", "url": "https://www.ensembl.org/id/ENSGALT00010037523.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021717.1", "url": "https://www.ensembl.org/id/ENSGALP00010021717.1" } ] } }, { "isoform_ac": "A0A8V0YZD1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL91/entry#A0A8V0YZD1-1", "sequence": { "sequence": "MAAAVRVLPASPNWYCSRCSDTSGDGRLFGFAARHRISVLDVSTATPTFHGELIGHTERIAAFAFCPHREHGALCASGSDDGSVRLWDAAGLVLRGEHGLHQNAITALHWSPLVKDLIVSGDEKGVIVCYWHSRSDSQQFFPEPRTIFCLTCSPHHENLVAVGYKDGMVVIIDISRKKEVLHRLRGHDDEIHCLAWCPVPGEGRLPAWQDELQEESDVPNGELKQDTAMKKSCYLASGSKDQTIRIWSCTRGRSVMTLKLPPTKRRGGAVDPAVKERIWLTVHWPCGRPTEIVSSSFGGELLHWDLTQPGKRKWTLLGSSEGQNHSRIVFNLCPLKHQDKELLLSISMDRDVKCWDLSTLDCSWTMPSLGGFVYSLAFSPVDPGCLAIGVGDSMIRVWNTLSMSNMFDVKTYWQSIKSKVTALAWHPTKEGCLAFGTDDGKVGIFDTLSSSAKNKPPQISSTYHKRTVYTLAWGPPTPPLSSGEEGEHPSVTLYSCAGEGIVFQHNPWKLSGEANDINKTIRDTNSIKHKLPARTEISWKPDGKLLALGNEDGSIEIFQAPNLKLLCTIQQHHKLINAIRWHHEHGSDPELSYLIASGSVNAIIYVHNLKSVIESTSESPLTITEPFRTLAGHTSKVTSLSWSPHHEGRLVSACYDGTAQVWDVMKEEPLCNYRGHQGRLLCVQWSPVDSDSIYTGADDFSVHKWLISKQEHTRPPQGKKSIELEKKRSIQPKVKAKKKKKPVGRSPAKQDQSDAVNGDESMKDTLLEENGVSDHEGEKEAQETELPDKDSIAVSKDTSLSAYDYSSLSSSKPFVTQKATPVKKDPPKEKPAPDASLKKRKPRSLLPFSTSMDHRSKDELHQDCLRLATCLKTKDHNEDVSPDLQNRIHLGLFTDRASLHNMIDVEGKYHLENGHPELFQQLMLWKGDMKGVLQAAAERGELTDQLVAMSPMVGYQAWVWTVEAFAKQLCFQEQYVKAASHLLSIHKVYEAVELLKVNNFYREAIVIAKARLRPEDPILKDLYTSWAALLEKDGHYSMAAKCYLGASSPYDAVKVMAKKGDAASLKTAAELALISGEEELSASLSFRCAQEMLLSRNWVGAQEVLQQQKTLFGQRLVFCLNELLCKCLSERNPCNRRSPVPPCYHSWELKRDASFFDMVIEVWQKVLGMDTTEKATCAWEQLHSIEHPPSTSNTHPKQVLFYISHDLTLAALSYQAAAWDEVVKSILGAVARSYDAGNFTLMQEICSIFLPEGCENLRDKLDSTNSQSMDACRSLEGFVACGLLYDLWWNPPKDPPAIQKACLDPALCPTEQTVLEQSCIPDHSSPEETPDQTAVETDENLNSTTEFNRCKTESDSKTNSVSLADRQSKLNGCKVLLSEAIAALQSTQRDIAEVQKILADMIHQHQQQRNNLQESTNGSIHENNVQQSSENELDEPLSDSSQIKRKDEVKETVTLPELTKRLMEAKQKLAEFPDSLKVFPFPDVLECCLVLLHIGAQCPPELHEQALDLLRKHGSGDIYEKAVRKFLT", "length": 1528, "header": "tr|A0A8V0YZD1-1|A0A8V0YZD1_CHICK Computationally mapped isoform of Gem nuclear organelle associated protein 5 OS=Gallus gallus OX=9031 GN=GEMIN5 PE=1 SV=1 CANONICAL=A0A8V0YL91-1" }, "locus": { "chromosome": "13", "start_pos": 11636571, "end_pos": 11619226, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010037516.1", "url": "https://www.ensembl.org/id/ENSGALT00010037516.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021713.1", "url": "https://www.ensembl.org/id/ENSGALP00010021713.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 477, "start_aa": "Thr", "end_pos": 477, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr477", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:416254", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416254", "resource": "KEGG Pathway" }, { "id": "R-GGA-191859", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-191859", "resource": "Reactome", "description": "snRNP Assembly" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZGD0-1", "protein_name": "Gem-associated protein 5", "gene_name": "Gemin5", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKPEPRTLPPSPNWYCARCSDAAPGGIFGFAARTSVFLVRVGPGAGASPGAPPFRVVGELVGHTERVSGFTFSHHPGQYNLCATSSDDGTVKIWDVETKAVVTEHALHQHTISALHWSPTVKDLIVSGDEKGVVFCYWLNRSDSQHLFTEPRAIFCLTCSPHHENLVAIGYKDGIVIIIDISKKGEVVHRLRGHDDEIHSIAWCPLSGEDCLSINQEENSEEPDIPNGKLIAETPITKGCYLATGSKDQTIRIWSCSRGRGVMVLKLPFLKRRSGGVDPTVKERLWLTLHWPKNQPTQLVSSCFGGELLLWDLTQSWRRKYTLFSTSAEGHNHSRIVFNLCPLKTEDGKQLLLSTSMDRDVKCWDMATLECCWTLPSLGGFAYSLAFSPVDVGSLAIGVGDGMIRVWNTLSIKNNYDVKNFWQGVKSKVTALCWHPNKEGCLAFGTDDGKVGLYDTCSNKPPQISSTYHKKTVYRLAWGPPVPPMSLGGEGDRPSLTLYSCGGEGIVLQHNPWKLSGEAFDINKLMRDTNSIRYKLPVHTEISWKGDGKVMALGNEDGSIEIFQVPNLKLLCTIQQHHKLVNAIVWHHEHGSRPELSCLLASGSNNAVIYVHNLKAVLESNPESPITITEPYRTLSGHTAKVTSLAWSPHHDGRLVSACYDGTAQVWDALREEPLFNFRGHRGRLLCVAWSPVDPECIYSGADDFCVYRWLTSMQDHSRPPQGKKCIELEKKRLSQFKPKLKKKKKPTLRLPIKQDSSIGNEDESVRENLAPVENGLSDQDGEEEAQEPELPPSPVVCGEPVSCTAVSLGLEKSKVTVTSKVASLKKEPPKEKPEALLKKRKARSMLPLSTSLDHRSKEELHRDCLVLATATHARAELHEDVSADLEERFHLGLFTDRAALYRMMETEGKGHLESGHPELFHQLMLWKGDLKGVLQAAAERGELTDSLVAVAPVAGYSVWLWAVEAFAKQLCFQDQYVKAASYLLSIHRVYEAVELLRSNHLYREAIAVAKARLRPEDPVLKDLYLSWGSILERDGHYAIAAKCYLGATSAYDAAKVLARKGDAASLRTAAELAAIAGESELAASLALRCAQELLLLKNWVGAQEALGLHESLQGQRLVFCLLELLCRHLEEKQPPEVRGPSSIYHQWATGSEGTLVQRVTGVWRSAFSVDTPEQCRAALQKLQDVKYPSATSNTPFRQLLLHVCHDLTLAMLSQQAASWEEAVPALLQAVVRSYTSGNFTLMQEIYSAFLPGGCDHLRDKLGDLSPTMAAFKSLEAFFIYGQLYEVWWSLCGPGSESSIWVWSAESTVSDKQSKPGDSASAEDMEQPLGPGLRLSAESERLLSACKELFSERHASLQTSQRTVAEVQETLAEMIRQHQKSQLCKATANGPNRDEPSQQAERAPSQPPSPTREERNAPVSLPELTRRLTEANERIAEFPESVKAWPFPDVLECCLVLLHIGSQCPGAVNPEMQQQAQKLLQKYGHTRAYRRHCQIRHT", "length": 1498 }, "evidence": [ { "id": "A0A8V0YL91", "url": "https://omabrowser.org/oma/group/A0A8V0YL91/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E1BJG3-1", "protein_name": "Gem-associated protein 5", "gene_name": "GEMIN5", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGQEPRTLPPSPNWYCSRCSDAVPGGLFGFAARTSVFLVRVGPGADAIPGTPPFRVIGELVGHTEKVSGFTFCHHPGQYNLCATSSDDGTVKIWDVGTKTVVTEHALHQHTISALHWSPRVKDLIVSGDEKGVVFCYWLNRNDSQHLFIEPRTIFCLTCSPHHEDLVAIGYKDGIVVIIDISKKGEVMHRLRGHDDEIHSIAWCPLSGEDCLSINQEENSEEPEMPNGKVITQTPVTKGCYLATGSKDQTIRIWSCSRGRGVMTLKLPFLKRRGGGVDPTVKERLWLTLHWPKDQPTQLVSSCFGGELLLWDLTQSWRRKYTLFSGSSEGQNHSRIVFNLCPLQTEDDKQLLLSISMDRDVKCWDMATLECCWSLPSLGGFAYSLAFSPVDTGCLAIGVGDGMIRVWNTLSIKNNYDVKHFWQGVKSKVTALCWHPTKEGCLAFGTDDGKVGLYDTYSNKPPQISSTYHKKTVYSLAWGPPVPAMALGEGDRPSLTLYSCGGEGIVLQHNPWKLSGEAFDINKLIRDTNSIKYKLPVHTEISWKADGKIMALGNEDGSIEIFKLPNLKLICSIQQHHKLVNTISWHHEHGSQPELSYLMASGSNNAVIYVHNLQTVIESNPQSPVTITEPYRTLSGHTAKITSLAWSPHHDGRLVSASYDGTAQVWDTLQEEPLCNFRGHRGRLLCVVWSPLDPDCIYSGADDFCVYKWLTSMQEHSRPPQGKKSIELEKKRLSQPKPKPKKKKKPTLRVPVRQELCDGNEEESVKESLGPIENGVSDQETEEEAREPEPPCGVTAAVSKEPIICTPAALGFEKSKSTINNKVTLLKKEVPKEKPEALIKKRKARSMLPLSTSLDHRSKEELHQDCLVLATAKHSTAGPNEDVSTDLEERFHLGLFTDRATLYRMIEVEGKSHLENGHPELFHQLMLWKGDLKGVLQTAAERGELTDNLVAMAPVAGYHVWVWAVEAFAKQLCFQDQYVKAASHLLSIHKVYEAVELLKSNHFYREAIAIAKARLRPEDPIIKDLYLSWGAILEKDGHYALAAKCYLGATSAYDAAKVLAKKGDAASLRTAAELASIVGENELSASLALRCAQELLLARNWVGAQEALQLHTSLKGQRLVFCLLELLSKHLEEKQLSEGKSSFSSYNDWPTDSEGSFVERVTAVWKSTFGLDSPEQYQAAFQQLQNIKYPSATSNTPSKQLLLHICHDLTLAVLSQEAGSWDAAVEGLLRAVIRSYDSANFTIMQEVHSAFLPQGCDHLRDKLGDHQSPTTPAFKSLKAFFIYGCLYEFWWSLSGPCPESSVWLRAAHRSKTSTEQSQEVDSVSPEETDPKPSQPEPSRTPELDVRLSEEGEQMQNACKELLSEKHAGLQNAQRTVAEVQETLAEMIRQHQKSQLCKSTANGPDKNEPEQEGQSLSHPQNQCKEEKNEPVSLPELTKRLTEANERIAKLPESIKTWPFPDVLECCLILLHIGSQCPSFVTQEMQQQAQEFLQKYGNTKVYKRHYQTLCT", "length": 1509 }, "evidence": [ { "id": "A0A8V0YL91", "url": "https://omabrowser.org/oma/group/A0A8V0YL91/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q54IY5-1", "protein_name": "Component of gems protein 5", "gene_name": "gemin5", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNIDSNIIKNENLINANNHTDRRDVHDSLAEAPEKITELKKNHWEELLPSSSNWYCTSVADCNENQIYIYACKSNVSIFNIKSKKFIGELNGHTDRVTSVGFFKRFESKNDESYKWCITGSDDKTVRIWKFNSNDDDHNEDTEIGDDFKHGSGGGGSDGGGGDDVNNFYGNKSSNFCIYYHQEHKAGVTCVVASPLVPDLVLSGDKAGALVIYRTLTNHVFPIPPIIGNNISISTLAFSPNHSDLVAIGYLNGIVLIYNFVIRSTVCKISAHSADVLSIVWFDSTIIQKNNIFHDNNINDQDDNNSNHRNRIFLATCSKDKAIKIWKQVGEKIESGFTNIYQFNPSKYSIQHSSSSGGGGINQNDKQRVWLTLSWSPESPQYLLSNSLTADVLIWDLINFKSPPEKFQSSHQRLIFNITQIPNSDGSLAKTTATTETTTKNKIKNKDKKQSQIKLNNKVITVSLDRQIIIWENLKAKIKIQGLGGFVYSIDTCSYSPNTFAIGCGDNTIRLWSPTENSKDAYESKTLWKGIQSKVTSLSICKDYGFSNSNLIAFGMDDGRVGVYNINTNQSKIFPGGHKNEIYEIIWKPPPTPTPQKNINNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNINNNNNNNSNNEQQPNKLYSIGNNEIYEWDYNDFNKSFTNMTPIIQQLNPKETFSKHKTDINFNLNGDMISIGYSDGTIDIFTSEFLFLTRIREHKKLINRVQWNHFKENEMILASASTDKKVIIYKLSKIGNQNENEKKIDNEKGKENENEKGKENENENENENENENENENENEIENIVNNNNENDTEIEIKNINKNENVDKEEMVENNNNNNIKYKIEILHQFIGHKNNVCSVSWSNVDPNLLGSASADGTVQVWNIKSKEAISNMRGHDGRVFTVCWSLLDPNLLVSGGEDQTVRLWNYSTQPFKTVTESQIKKSPQPELSISLNKKITEQQQQQQQPQSPIKSNPDQSNNPSLVPPILLTSVTSTSNTTATATTITQITESLPKKRPIFLLNKDIVQRQDSSQYVVPLAKYFTTNDQDSINTNETKQEYEFGSNSENNNSKIEAIFSEKKEIINKLVQKESLELLKIDDVENYISLNSWNPANLKQALYQVIKNGKLTGNIVSLSIQAGREIFESICNLYSQQLICIGDYHLAVSYLLMIGKVNEAIEVYRNTLLFQEAIILAKSRFLPDDPIINKLFTEWAKQTETSHPIHSIKCYLATINDQSLNSKQELLKLLSSVQTKQIIKIQSDLEQILK", "length": 1276 }, "evidence": [ { "id": "A0A8V0YL91", "url": "https://omabrowser.org/oma/group/A0A8V0YL91/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q8BX17-1", "protein_name": "Gem-associated protein 5", "gene_name": "Gemin5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKPEPRTLPPSPNWYCSRCSDAAPGGIFGFAARTSVFLVRVGPGAGASPGAPPFRVVGELVGHTERVSGFTFSHHPGQYNLCATSSDDGTVKVWDVETKTVVTEHTLHQHTISALHWSPTVKDLIVSGDEKGVVFCYWLNRNDSQHLFTEPRTIFCLTCSPHHENLVAIGYKDGIVVIIDISKKGEVIHRLRGHDDEIHSIAWCPLSGEDCLSISQEENSEEPDIPNGKLIAETPITKGCYLATGSKDQTIRIWSCSRGRGVMVLKLPFLKRRSGGVDPTVKERLWLTLHWPKNQPTQLVSSCFGGELLLWDLTQSWRRKYTLFSTSAEGHNHSRIVFNLCSLKTEDGKQLLLSTSMDRDVKCWDMATLECCWTLPSLGGFAYSLAFSPVDVGSLAIGVGDGMIRVWNTLSIKNNYDVKNFWQGVKSKVTALCWHPNKEGCLAFGTDDGKVGLYDTCSNKPPQISSTYHKKTVYRLAWGPPVPPMSLGGEGDRPSLTLYSCGGEGVVLQHNPWKLSGEAFDINKLVRDTNSIRYKLPVHTEISWKGDGKVLALGNEDGSIEIFQVPNLRLLCTIQQHHKLVNAIVWHHEHGSRPELSCLLASGSNNAVIYVHNLKAVLESNPESPITITEPYRTLSGHTAKITSLAWSPHHDGRLVSACYDGTAQVWDALREEPLFNFRGHRGRLLCVAWSPVDPECIYSGADDFCVYRWLTSMQDHSRPPQGKKCIELEKKRLSQFKPKLKKKKKPTLRLPVKQDSSVGNEDESVKENSGPAENGLSDQDGEEEAQEPELPPSPVVCVEPVSCTDICSGFEKSKVTVSSKATSLKKEPAKEKPEALLKKRKARSMLPLSTSLDHRSKEELHRDCLVLATATHAKAELNEDVSADLEERFHLGLFTDRATLYRMMETEGKGHLESGHPELFHQLMLWKGDLKGVLQAAAERGELTDSLVAVAPVAGYSVWLWAVEAFAKQLCFQDQYVKAASYLLSIHKVYEAVELLKSNHLYREAIAVAKARLRPEDPVLKELYLSWGSILERDGHYAIAAKCYLGATSAYDAAKVLARKGDAASLRTAAELAAIAGEHELAASLALRCAQELLLMKNWVGAQEALGLHESLQGQRLVFCLLELLCRHLEEKQPLEVRGPSSIYHQWATGSEGTLVQRVTGVWRSAFSVDTPEQCQAALQKLQDVKYPSATSNTPFRQLLLHVCHDLTLAMLSQQAAAWEEAVPALLQAVVRSYTSGNFTLMQEIYSAFLPGGCDHLRDKLGDLSPAMAAYKSLEAFCIYGQLYEVWWSLCGPGPESSVWVLSAESTVSDKQSKPEDSASAEDMEQPPGPGPRLSAESERLLSACKELFSERHASLQTSQRTVAEVQETLAEMIRQHQKSQLCKATTNGPSRDEPSRDEPSQEAERAPSQPPSPTEERNAPVSLPELTRRLTEANERIAEFPESVKAWPFPDVLECCLVLLHIGSQCPDAVDPEMQQQAQELLHKYGHTRAYRRHCQSRHT", "length": 1502 }, "evidence": [ { "id": "A0A8V0YL91", "url": "https://omabrowser.org/oma/group/A0A8V0YL91/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8TEQ6-1", "protein_name": "Gem-associated protein 5", "gene_name": "GEMIN5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGQEPRTLPPSPNWYCARCSDAVPGGLFGFAARTSVFLVRVGPGAGESPGTPPFRVIGELVGHTERVSGFTFSHHPGQYNLCATSSDDGTVKIWDVETKTVVTEHALHQHTISTLHWSPRVKDLIVSGDEKGVVFCYWFNRNDSQHLFIEPRTIFCLTCSPHHEDLVAIGYKDGIVVIIDISKKGEVIHRLRGHDDEIHSIAWCPLPGEDCLSINQEETSEEAEITNGNAVAQAPVTKGCYLATGSKDQTIRIWSCSRGRGVMILKLPFLKRRGGGIDPTVKERLWLTLHWPSNQPTQLVSSCFGGELLQWDLTQSWRRKYTLFSASSEGQNHSRIVFNLCPLQTEDDKQLLLSTSMDRDVKCWDIATLECSWTLPSLGGFAYSLAFSSVDIGSLAIGVGDGMIRVWNTLSIKNNYDVKNFWQGVKSKVTALCWHPTKEGCLAFGTDDGKVGLYDTYSNKPPQISSTYHKKTVYTLAWGPPVPPMSLGGEGDRPSLALYSCGGEGIVLQHNPWKLSGEAFDINKLIRDTNSIKYKLPVHTEISWKADGKIMALGNEDGSIEIFQIPNLKLICTIQQHHKLVNTISWHHEHGSQPELSYLMASGSNNAVIYVHNLKTVIESSPESPVTITEPYRTLSGHTAKITSVAWSPHHDGRLVSASYDGTAQVWDALREEPLCNFRGHRGRLLCVAWSPLDPDCIYSGADDFCVHKWLTSMQDHSRPPQGKKSIELEKKRLSQPKAKPKKKKKPTLRTPVKLESIDGNEEESMKENSGPVENGVSDQEGEEQAREPELPCGLAPAVSREPVICTPVSSGFEKSKVTINNKVILLKKEPPKEKPETLIKKRKARSLLPLSTSLDHRSKEELHQDCLVLATAKHSRELNEDVSADVEERFHLGLFTDRATLYRMIDIEGKGHLENGHPELFHQLMLWKGDLKGVLQTAAERGELTDNLVAMAPAAGYHVWLWAVEAFAKQLCFQDQYVKAASHLLSIHKVYEAVELLKSNHFYREAIAIAKARLRPEDPVLKDLYLSWGTVLERDGHYAVAAKCYLGATCAYDAAKVLAKKGDAASLRTAAELAAIVGEDELSASLALRCAQELLLANNWVGAQEALQLHESLQGQRLVFCLLELLSRHLEEKQLSEGKSSSSYHTWNTGTEGPFVERVTAVWKSIFSLDTPEQYQEAFQKLQNIKYPSATNNTPAKQLLLHICHDLTLAVLSQQMASWDEAVQALLRAVVRSYDSGSFTIMQEVYSAFLPDGCDHLRDKLGDHQSPATPAFKSLEAFFLYGRLYEFWWSLSRPCPNSSVWVRAGHRTLSVEPSQQLDTASTEETDPETSQPEPNRPSELDLRLTEEGERMLSTFKELFSEKHASLQNSQRTVAEVQETLAEMIRQHQKSQLCKSTANGPDKNEPEVEAEQPLCSSQSQCKEEKNEPLSLPELTKRLTEANQRMAKFPESIKAWPFPDVLECCLVLLLIRSHFPGCLAQEMQQQAQELLQKYGNTKTYRRHCQTFCM", "length": 1508 }, "evidence": [ { "id": "A0A8V0YL91", "url": "https://omabrowser.org/oma/group/A0A8V0YL91/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 6, "go_terms": [ { "name": "U4 snRNA binding", "id": "GO:0030621", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030621", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YL91", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL91" } ], "pmid": "" }, { "name": "ribosome binding", "id": "GO:0043022", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043022", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YL91", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL91" } ], "pmid": "" }, { "name": "RNA 7-methylguanosine cap binding", "id": "GO:0000340", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000340", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YL91", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL91" } ], "pmid": "" }, { "name": "mRNA 3'-UTR binding", "id": "GO:0003730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003730", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YL91", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL91" } ], "pmid": "" }, { "name": "U4atac snRNA binding", "id": "GO:0030622", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030622", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YL91", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL91" } ], "pmid": "" }, { "name": "U1 snRNA binding", "id": "GO:0030619", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030619", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YL91", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL91" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YL91", "url": 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"pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "regulation of translation", "id": "GO:0006417", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006417", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YL91", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL91" } ], "pmid": "" }, { "name": "spliceosomal snRNP assembly", "id": "GO:0000387", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000387", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YL91", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL91" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1238, "end_pos": 1240, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1342, "end_pos": 1344, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1417, "end_pos": 1419, "annotation": "n_glycosylation_sequon" }, { "start_pos": 324, "end_pos": 326, "annotation": "n_glycosylation_sequon" }, { "start_pos": 518, "end_pos": 520, "annotation": 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] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YLA5-1", "uniprot_ac": "A0A8V0YLA5", "uniprot_id": "A0A8V0YLA5_CHICK", "mass": { "chemical_mass": 123515.0, "monoisotopic_mass": 123515.0 }, "refseq": { "ac": "XP_004947826", "name": "dyslexia-associated protein KIAA0319-like protein homolog isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004947826" }, "gene_names": [ { "name": "KIAA0319L", "type": "recommended", "evidence": [ { "id": "A0A8V0YLA5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLA5" } ] }, { "name": "KIAA0319L", "type": "synonym", "evidence": [ { "id": "XP_004947826", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004947826" } ] } ], "protein_names": [ { "name": "KIAA0319 like", "type": "synonym", "evidence": [ { "id": "A0A8V0YLA5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLA5/entry#names_and_taxonomy" } ] }, { "name": "dyslexia-associated protein KIAA0319-like protein homolog isoform X1", "type": "synonym", "evidence": [ { "id": "XP_004947826", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004947826" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 1% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052554.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_004947826.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004947826", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004947826" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLA5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLA5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "KIAA0319L", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLA5", "locus": { "chromosome": "23", "start_pos": 4699946, "end_pos": 4673342, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013772", "url": "https://www.ensembl.org/id/ENSGALG00010013772" } ] } } ], "crossref": [ { "id": "A0A8V0YLA5", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YLA5", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00146", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00146", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "419634", "url": "https://www.ncbi.nlm.nih.gov/gene/419634", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000601", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000601", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003961", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003961", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013980", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013980", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR022409", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022409", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029865", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029865", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035986", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035986", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056502", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056502", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:419634", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419634", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "AYVIPDE", "url": "https://omabrowser.org/oma/group/AYVIPDE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YLA5", "url": "https://www.orthodb.org/?gene=A0A8V0YLA5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YNJ6", "url": "https://www.orthodb.org/?gene=A0A8V0YNJ6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YNK4", "url": "https://www.orthodb.org/?gene=A0A8V0YNK4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46182", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46182", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46182:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46182:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF22352", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22352", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23597", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23597", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23620", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23620", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_004947826", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004947826", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YLA5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLA5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLA5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLA5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YNJ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNJ6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YNJ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNJ6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YNK4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNK4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YNK4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNK4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEKRLEAKLSISAPFLPRYCWGRHVRELRSLQLLYLCACLCALCSSTDANWNRSKCEPGKILLGGRLQSWEDHHLRLLEGFHTVQSCQTACCQSPACDAFWFLENMCIQVNCTVPATCQANRTGTSDSVLVFLKKSKSTEHFLKLQMENDVKAWLRRWSDWDIPVQGKKRLRRSFQKQSLAINRVQLLQGDTAARPSGEAAARASHSTSRSSRSDAERLKDQVLKHLGEDRPVPEAHPNQKKDVLKNGQNPQEQKTKSPFPPKSNNVNGSGDADSVGFPQIHVGTSAPESPVLATLSSPVALSLTAAGKTEKPELLDDASVQTHSSDTLPTVSPAQGKSTMKMQAATSVPSGVPTNSSVSPVQANTAVSLSTTATTPVMKELVVSAGDSVEVTLPKNEVQLNAFVLPEPPPGTTYSYEWELITHPKDYSGEMEGKHSQTLKLSKLTVGLYEFKVVVDGENAHGEGYVNVTVNPKPRVNRPPVAIVSPQFQEISLPTISTVIDGSQSTDDDKIVSYHWEELKGPLREEKVSSDTAILTLTNLVPGNYTFSLTVVDSDGASNSTTANLTVNKAVDYPPVANAGPNQVITLPQNSITLYGNQSTDDHSIVSYEWLLSPNSKGKVMEMQGVRTPVLQLSAMQEGDYTYQLIVTDSAGHQSTAEVTVIVQPENNKPPKADAGPDKELTLPVDSTTLDGSKSSDDQKIVSFLWEKTRGPDGVKLENANSSIATVTGLQVGTYEFTLTVKDERNLQSQSSVNVIVKEEINKPPVAKIAGNVVITLPTNTAELDGSKSSDDKGIVSYLWTRDEGSPAAGEVLNNSDHHPVLLLSNLVEGTYTFHLRVTDAKGESDVERTTVEVKPDPRKNNLVEIILDVNVSQLTERQKGMFIRQIGVLLGVLDSDITVQKIQPYTEQSTKMVFFVQNQPPHQIFKGREVAWTLKNELRKQQSDFLIFRALEINTVTCQLNCSEHGRCDSFTKRCVCDPFWMENFIKVQMGDGESNCEWSVLYVIIASFVIVVAFGILSWMVICCCKRRKGKSKRKSKYKILDATDQESLELKPNPKAGGRQKAQVLNTSLMHSESELDSDEAIFTWPDREKGKLLRSQNGSLRNGQVALKAKSQREEIL", "length": 1122, "header": "tr|A0A8V0YLA5-1|A0A8V0YLA5_CHICK Isoform 1 of KIAA0319 like OS=Gallus gallus OX=9031 GN=KIAA0319L PE=4 SV=1 CANONICAL=A0A8V0YLA5-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YLA5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLA5/entry#A0A8V0YLA5-1", "sequence": { "sequence": "MEKRLEAKLSISAPFLPRYCWGRHVRELRSLQLLYLCACLCALCSSTDANWNRSKCEPGKILLGGRLQSWEDHHLRLLEGFHTVQSCQTACCQSPACDAFWFLENMCIQVNCTVPATCQANRTGTSDSVLVFLKKSKSTEHFLKLQMENDVKAWLRRWSDWDIPVQGKKRLRRSFQKQSLAINRVQLLQGDTAARPSGEAAARASHSTSRSSRSDAERLKDQVLKHLGEDRPVPEAHPNQKKDVLKNGQNPQEQKTKSPFPPKSNNVNGSGDADSVGFPQIHVGTSAPESPVLATLSSPVALSLTAAGKTEKPELLDDASVQTHSSDTLPTVSPAQGKSTMKMQAATSVPSGVPTNSSVSPVQANTAVSLSTTATTPVMKELVVSAGDSVEVTLPKNEVQLNAFVLPEPPPGTTYSYEWELITHPKDYSGEMEGKHSQTLKLSKLTVGLYEFKVVVDGENAHGEGYVNVTVNPKPRVNRPPVAIVSPQFQEISLPTISTVIDGSQSTDDDKIVSYHWEELKGPLREEKVSSDTAILTLTNLVPGNYTFSLTVVDSDGASNSTTANLTVNKAVDYPPVANAGPNQVITLPQNSITLYGNQSTDDHSIVSYEWLLSPNSKGKVMEMQGVRTPVLQLSAMQEGDYTYQLIVTDSAGHQSTAEVTVIVQPENNKPPKADAGPDKELTLPVDSTTLDGSKSSDDQKIVSFLWEKTRGPDGVKLENANSSIATVTGLQVGTYEFTLTVKDERNLQSQSSVNVIVKEEINKPPVAKIAGNVVITLPTNTAELDGSKSSDDKGIVSYLWTRDEGSPAAGEVLNNSDHHPVLLLSNLVEGTYTFHLRVTDAKGESDVERTTVEVKPDPRKNNLVEIILDVNVSQLTERQKGMFIRQIGVLLGVLDSDITVQKIQPYTEQSTKMVFFVQNQPPHQIFKGREVAWTLKNELRKQQSDFLIFRALEINTVTCQLNCSEHGRCDSFTKRCVCDPFWMENFIKVQMGDGESNCEWSVLYVIIASFVIVVAFGILSWMVICCCKRRKGKSKRKSKYKILDATDQESLELKPNPKAGGRQKAQVLNTSLMHSESELDSDEAIFTWPDREKGKLLRSQNGSLRNGQVALKAKSQREEIL", "length": 1122, "header": "tr|A0A8V0YLA5-1|A0A8V0YLA5_CHICK Isoform 1 of KIAA0319 like OS=Gallus gallus OX=9031 GN=KIAA0319L PE=4 SV=1 CANONICAL=A0A8V0YLA5-1" }, "locus": { "chromosome": "23", "start_pos": 4698637, "end_pos": 4674539, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033071.1", "url": "https://www.ensembl.org/id/ENSGALT00010033071.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019555.1", "url": "https://www.ensembl.org/id/ENSGALP00010019555.1" } ] } }, { "isoform_ac": "A0A8V0YNJ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLA5/entry#A0A8V0YNJ6-1", "sequence": { "sequence": "MHIFSAGLPYHANWNRSKCEPGKILLGGRLQSWEDHHLRLLEGFHTVQSCQTACCQSPACDAFWFLENMCIQVNCTVPATCQANRTGTSDSVLVFLKKSKSTEHFLKLQMENDVKAWLRRWSDWDIPVQGKKRLRRSFQKQSLAINRVQLLQGDTAARPSGEAAARASHSTSRSSRSDAERLKDQVLKHLGEDRPVPEAHPNQKKDVLKNGQNPQEQKTKSPFPPKSNNVNGSGDADSVGFPQIHVGTSAPESPVLATLSSPVALSLTAAGKTEKPELLDDASVQTHSSDTLPTVSPAQGKSTMKMQAATSVPSGVPTNSSVSPVQANTAVSLSTTATTPVMKELVVSAGDSVEVTLPKNEVQLNAFVLPEPPPGTTYSYEWELITHPKDYSGEMEGKHSQTLKLSKLTVGLYEFKVVVDGENAHGEGYVNVTVNPKPRVNRPPVAIVSPQFQEISLPTISTVIDGSQSTDDDKIVSYHWEELKGPLREEKVSSDTAILTLTNLVPGNYTFSLTVVDSDGASNSTTANLTVNKAVDYPPVANAGPNQVITLPQNSITLYGNQSTDDHSIVSYEWLLSPNSKGKVMEMQGVRTPVLQLSAMQEGDYTYQLIVTDSAGHQSTAEVTVIVQPENNKPPKADAGPDKELTLPVDSTTLDGSKSSDDQKIVSFLWEKTRGPDGVKLENANSSIATVTGLQVGTYEFTLTVKDERNLQSQSSVNVIVKEEINKPPVAKIAGNVVITLPTNTAELDGSKSSDDKGIVSYLWTRDEGSPAAGEVLNNSDHHPVLLLSNLVEGTYTFHLRVTDAKGESDVERTTVEVKPDPRKNNLVEIILDVNVSQLTERQKGMFIRQIGVLLGVLDSDITVQKIQPYTEQSTKMVFFVQNQPPHQIFKGREVAWTLKNELRKQQSDFLIFRALEINTVTCQLNCSEHGRCDSFTKRCVCDPFWMENFIKVQMGDGESNCEWSVLYVIIASFVIVVAFGILSWMVICCCKRRKGKSKRKSKYKILDATDQESLELKPNPKAGGRQKAQVLNTSLMHSESELDSDEAIFTWPDREKGKLLRSQNGSLRNGQVALKAKSQREEIL", "length": 1085, "header": "tr|A0A8V0YNJ6-1|A0A8V0YNJ6_CHICK Computationally mapped isoform of KIAA0319 like OS=Gallus gallus OX=9031 GN=KIAA0319L PE=4 SV=1 CANONICAL=A0A8V0YLA5-1" }, "locus": { "chromosome": "23", "start_pos": 4698637, "end_pos": 4677037, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033057.1", "url": "https://www.ensembl.org/id/ENSGALT00010033057.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019549.1", "url": "https://www.ensembl.org/id/ENSGALP00010019549.1" } ] } }, { "isoform_ac": "A0A8V0YNK4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLA5/entry#A0A8V0YNK4-1", "sequence": { "sequence": "MEKRLEAKLSISAPFLPRYCWGRHVRELRSLQLLYLCACLCALCSSTDANWNRSKCEPGKILLGGRLQSWEDHHLRLLEGFHTVQSCQTACCQSPACDAFWFLENMCIQVNCTVPATCQANRTGTSDSVLVFLKKSKSTEHFLKLQMENDVKAWLRRWSDWDIPVQGKKRLRRSFQKQSLAINRVQLLQGDTAARPSGEAAARASHSTSRSSRSDAERLKDQVLKHLGEDRPVPEAHPNQKKDVLKNGQNPQEQKTKSPFPPKSNNVNGSGDADSVGFPQIHVGTSAPESPVLATLSSPVALSLTAAGKTEKPELLDDASVQTHSSDTLPTVSPAQGKSTMKMQAATSVPSGVPTNSSVSPVQANTAVSLSTTATTPVMKELVVSAGDSVEVTLPKNEVQLNAFVLPEPPPGTTYSYEWELITHPKDYSGEMEGKHSQTLKLSKLTVGLYEFKVVVDGENAHGEGYVNVTVNPKPRVNRPPVAIVSPQFQEISLPTISTVIDGSQSTDDDKIVSYHWEELKGPLREEKVSSDTAILTLTNLVPGNYTFSLTVVDSDGASNSTTANLTVNKAVDYPPVANAGPNQVITLPQNSITLYGNQSTDDHSIVSYEWLLSPNSKGKVMEMQGVRTPVLQLSAMQEGDYTYQLIVTDSAGHQSTAEVTVIVQPENNKPPKADAGPDKELTLPVDSTTLDGSKSSDDQKIVSFLWEKTRGPDGVKLENANSSIATVTGLQVGTYEFTLTVKDERNLQSQSSVNVIVKEEINKPPVAKIAGNVVITLPTNTAELDGSKSSDDKGIVSYLWTRDEGSPAAGEVLNNSDHHPVLLLSNLVEGTYTFHLRVTDAKGESDVERTTVEVKPDPRKNNLVEIILDVNVSQLTERQKGMFIRQIGVLLGVLDSDITVQKIQPYTEQSTKMVFFVQNQPPHQIFKGREVAWTLKNELRKQQSDFLIFRALEINTVKWSVLYVIIASFVIVVAFGILSWMVICCCKRRKGKSKRKSKYKILDATDQESLELKPNPKAGGRQKAQVLNTSLMHSESELDSDEAIFTWPDREKGKLLRSQNGSLRNGQVALKAKSQREEIL", "length": 1081, "header": "tr|A0A8V0YNK4-1|A0A8V0YNK4_CHICK Computationally mapped isoform of KIAA0319 like OS=Gallus gallus OX=9031 GN=KIAA0319L PE=4 SV=1 CANONICAL=A0A8V0YLA5-1" }, "locus": { "chromosome": "23", "start_pos": 4698637, "end_pos": 4674539, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033078.1", "url": "https://www.ensembl.org/id/ENSGALT00010033078.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019559.1", "url": "https://www.ensembl.org/id/ENSGALP00010019559.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:419634", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419634", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6APE1-1", "protein_name": "KIAA0319 like", "gene_name": "Kiaa0319l", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPESGAWVLVQRRKGAGRPTRARSKRLRAWTSSLVRSSLSATPPPTLGSRLELRFRRVGAGGLAQHEGVLVPPLWKAMEKRLGVKPSTTSWVLPGYCWQISVKPPRSLYLVYSFFCLSVLWLSTDANESRCHQGKTLYGAGLKTEGENHLRLLPGSLSFQACWAACCQDPACHALWWLEGMCLQADCSKPQSCQPFRTDSSHSVLIVFQKSQTAKDLGLLPEDGEPHLRRGWGRTSWRRQSLPGAPLTLSIPSSDHQSLLRERQKRDHPSVVPTRVVIQQAKANHSEEASAASPRASAEVRKTITVPSSFTSNHTTQTPEWPKNVSIPTEPSGHFTLASSTQQVKSTEHSPTDTPLPVAPSYSSATPTAQTSSQSTSAPRPVVKELVVSAGKSVQITLPKNEVQLNAFALPEPEPGETYTYDWQLITHPTDYSGEVERKHSQSLQLSKLTPGLYEFKVIVDGQNAHGEGYVNVTVKPEPRKNRPPVAVVSPQFQEISLPTTSTIIDGSQSTDDDKIVQYHWEELKGPLREEKISEDTAILKLSKLVPGNYTFSLTVVDSDGATNSTTASLTVNKAVDYPPVANAGPNQVITLPQNSITLFGNQSTDDHGISSYEWSLSPSSKGKVVEMQGVRTPALQLSAMQEGDYTYQLTVTDTAGQQATAQVTVIVQPENNKPPQADAGPDKELTLPVDSTTLDGSKSTDDQRVVSYLWEQSRGPDGVQLENANSSVATVTGLQVGTYVFTLTVKDERNLQSQSSVSVIVKEEINKPPVAKITGNVVVTLPTSTVELDGSRSSDDKGIVSYLWTRDEASPAAGEVLNHSDHHPVLFLSNLVEGSYTFHLKVTDAKGESDTDRTTVEVKPDPRKSNLVEIILDVNVSQLTERLKGMFIRQIGVLLGVLDSDIIVQKIQPYTEQSTKMLFFVQNDPPHQFFKGREVAAMLKSELRKQKADFLIFRALEINTVTCQLNCSDHGHCDSFTKRCVCDPFWMENFIKVQLRDGDSNCEWSVLYVIIASFVIVVALGILSWTTVCCCKRQDGKPKRKSRYKILDATDQESLELKPTSRAGSKQKGPTMSSSLMHSESELDSDDAIFTWPDREKGKLLHGQNGSVPNGQTPLKTRSPREEIL", "length": 1126 }, "evidence": [ { "id": "A0A8V0YLA5", "url": "https://omabrowser.org/oma/group/A0A8V0YLA5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1ML49-1", "protein_name": "KIAA0319 like", "gene_name": "KIAA0319L", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MEKLGIKPSRASWLLSRFCWQTSVKQLKSLYLFYFCFCFSALWLSTDAKESRCQRVKTQFGVGLRSRGENHLRLLEGTPSLQSCWAACCQDSACHAFWWLEGMCLQADCSRPQSCQAFRTDSSSSMLVFFKKFQIEDDLDFLPEDDVPHILGLDWSRASWRRESPPQTPLRPTLSSDQWSLIRKLRKRENPSEEVAAVTQPSKTNELGDLNSTGSAEVHSTDTIFNPLTTDLSVKIPGRSDVSVQREASEDPGATPSIQQVKSPEKVQIAHPLPVAPSYSYATPTPQASFQSTSTPLPVIKELVVSAGNSVQITLPKNEVQLNAFVLPEPDAGEAYTYDWQLITHPRDYSGEMEGEHSKILKLSKLTPGLYEFKVIVDGQNAHGEGYVNVTVKPEPRKNRPPVAIVSPQYQEISLPTTSTVIDGSQSTDDDKIVQYHWEELKGPLREKKISEDTAILKLSKLVPGNYTFSLTVVDSDGATNSTTARLTVNKAVDYPPVANAGPNQVITLPQNSITLFGNQSTDDHGITSYEWSLSPNSKGKVMEMQGVRTPTLQLSAMQEGDYTYQLTVTDTVGQQATAQVTVIVQPENNKPPQADAGPDKELTLPVDSTTLDGSKSSDDQKIISYLWEKTQGPDGVQLENANSSVATVTGLQVGTYVFTLTVKDERNLQSQSSVNVIVKEEMNKAPVAKIAGNVVITLPTDTAELDGSKSSDDKGIVSYLWTRDEGSPAAGEVLNRSDHHPVLFLSNLVEGTYTFHLKVTDAKGESDVDRTTVEVKPDPRKNSLVELILDVNVSQLTERLKGMFIRQIGVLLGVLDSDIIVQKIQPYTEQSTKMVFFVQNEPPHQIFKGHEVAAMLKSELQKQKADFLIFRALEISTVTCQLNCSDHGHCDSFTKRCVCDPFWMENFIKVQLRDGDSNCEWSVLYVIIASFLIVVALGILSWTVICCCKRQKGKPKRKSKYKILDATDQESLELKPTSRAGVKQKGPALSSSLMHSESELDSDDAIFTWPDREKGKLLHGQNGSVPNGQTPLKVRSPREEIL", "length": 1043 }, "evidence": [ { "id": "A0A8V0YLA5", "url": "https://omabrowser.org/oma/group/A0A8V0YLA5/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q8IZA0-1", "protein_name": "Dyslexia-associated protein KIAA0319-like protein", "gene_name": "KIAA0319L", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEKRLGVKPNPASWILSGYYWQTSAKWLRSLYLFYTCFCFSVLWLSTDASESRCQQGKTQFGVGLRSGGENHLWLLEGTPSLQSCWAACCQDSACHVFWWLEGMCIQADCSRPQSCRAFRTHSSNSMLVFLKKFQTADDLGFLPEDDVPHLLGLGWNWASWRQSPPRAALRPAVSSSDQQSLIRKLQKRGSPSDVVTPIVTQHSKVNDSNELGGLTTSGSAEVHKAITISSPLTTDLTAELSGGPKNVSVQPEISEGLATTPSTQQVKSSEKTQIAVPQPVAPSYSYATPTPQASFQSTSAPYPVIKELVVSAGESVQITLPKNEVQLNAYVLQEPPKGETYTYDWQLITHPRDYSGEMEGKHSQILKLSKLTPGLYEFKVIVEGQNAHGEGYVNVTVKPEPRKNRPPIAIVSPQFQEISLPTTSTVIDGSQSTDDDKIVQYHWEELKGPLREEKISEDTAILKLSKLVPGNYTFSLTVVDSDGATNSTTANLTVNKAVDYPPVANAGPNQVITLPQNSITLFGNQSTDDHGITSYEWSLSPSSKGKVVEMQGVRTPTLQLSAMQEGDYTYQLTVTDTIGQQATAQVTVIVQPENNKPPQADAGPDKELTLPVDSTTLDGSKSSDDQKIISYLWEKTQGPDGVQLENANSSVATVTGLQVGTYVFTLTVKDERNLQSQSSVNVIVKEEINKPPIAKITGNVVITLPTSTAELDGSKSSDDKGIVSYLWTRDEGSPAAGEVLNHSDHHPILFLSNLVEGTYTFHLKVTDAKGESDTDRTTVEVKPDPRKNNLVEIILDINVSQLTERLKGMFIRQIGVLLGVLDSDIIVQKIQPYTEQSTKMVFFVQNEPPHQIFKGHEVAAMLKSELRKQKADFLIFRALEVNTVTCQLNCSDHGHCDSFTKRCICDPFWMENFIKVQLRDGDSNCEWSVLYVIIATFVIVVALGILSWTVICCCKRQKGKPKRKSKYKILDATDQESLELKPTSRAGIKQKGLLLSSSLMHSESELDSDDAIFTWPDREKGKLLHGQNGSVPNGQTPLKARSPREEIL", "length": 1049 }, "evidence": [ { "id": "A0A8V0YLA5", "url": "https://omabrowser.org/oma/group/A0A8V0YLA5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLA5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLA5" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLA5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLA5" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLA5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLA5" } ], "pmid": "" }, { "name": "trans-Golgi network membrane", "id": "GO:0032588", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032588", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLA5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLA5" } ], "pmid": "" }, { "name": "cytoplasmic vesicle", "id": "GO:0031410", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031410", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLA5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLA5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "neuron migration", "id": "GO:0001764", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001764", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLA5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLA5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1070, "end_pos": 1072, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1102, "end_pos": 1104, "annotation": "n_glycosylation_sequon" }, { "start_pos": 111, "end_pos": 113, "annotation": "n_glycosylation_sequon" }, { "start_pos": 121, "end_pos": 123, "annotation": "n_glycosylation_sequon" }, { "start_pos": 268, "end_pos": 270, "annotation": "n_glycosylation_sequon" }, { "start_pos": 356, "end_pos": 358, "annotation": "n_glycosylation_sequon" }, { "start_pos": 468, "end_pos": 470, "annotation": "n_glycosylation_sequon" }, { "start_pos": 52, "end_pos": 54, "annotation": "n_glycosylation_sequon" }, { "start_pos": 545, "end_pos": 547, "annotation": "n_glycosylation_sequon" }, { "start_pos": 560, "end_pos": 562, "annotation": "n_glycosylation_sequon" }, { "start_pos": 565, "end_pos": 567, "annotation": "n_glycosylation_sequon" }, { "start_pos": 598, "end_pos": 600, "annotation": "n_glycosylation_sequon" }, { "start_pos": 722, "end_pos": 724, "annotation": "n_glycosylation_sequon" }, { "start_pos": 815, "end_pos": 817, "annotation": "n_glycosylation_sequon" }, { "start_pos": 872, "end_pos": 874, "annotation": 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Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052533.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015137671.2. 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"MKLEVFSQHYEDKLSAGSDQEGSGSLSPAPADSELGSDGDCAANSPGGSAGSSGRPPPPTPAPQPPPPPPAPTEGGKGKPYTRRPKPPYSYIALIAMAIRDSAGGRLTLAEINDYLMSRFPFFRGAYTGWRNSVRHNLSLNDCFVKVLRDPARPWGKDNYWMLNPSSEYTFADGVFRRRRKRLSRAAPPPPPPPSARPAAAPQPPPPQPPQEAAGAGAASPAATEEEEEAAAGGGGAAGGGAKFSSSFAIESLLRRPAGPRAAPQPPPPARLLWPPPAGPHLLPAHHYPLLPYAQPSPPAAALYGGGLVQLCAYGLGEPPLLLGGPHGHPQGQPPAERPRAPLFAGAAFPGGSPPYVPLRAPRPTAGSSTPFRPYAVETPLA", "length": 382, "header": "tr|A0A8V0YLB3-1|A0A8V0YLB3_CHICK Isoform 1 of Forkhead box Q1 OS=Gallus gallus OX=9031 GN=FOXQ1 PE=4 SV=1 CANONICAL=A0A8V0YLB3-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YLB3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLB3/entry#A0A8V0YLB3-1", "sequence": { "sequence": 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"prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 365, "start_aa": "Thr", "end_pos": 365, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr365", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 60, "start_aa": "Thr", "end_pos": 60, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr60", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 73, "start_aa": "Thr", "end_pos": 73, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr73", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:107052626", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:107052626", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3Q1M7S9-1", "protein_name": "Forkhead box Q1", "gene_name": "FOXQ1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MKLEVFGPRAGLGDKPGSDLEGAGGSDAPSPLSAAGDDSLGSDGDCAANSPAAGSGERSAGGGPGAEEAGAAGAAGATAGPRAGGAGSGGAGGGEGARGKPYTRRPKPPYSYIALIAMAIRDSAGGRLTLAEINEYLMGKFPFFRGSYTGWRNSVRHNLSLNDCFVKVLRDPSRPWGKDNYWMLNPNSEYTFADGVFRRRRKRLSHRAAAPGPALRPPDGAPPPPAPAAAAPASPRARSPARPEGRASPAGRFSGPFAIDSILSKPFRSRRAGDAGPGARPPWGAAPCPPPPAYPALLQAAPAGALLPLCAFGAAEPPGLLARGAEAPPLLLAPLAAPAPAKPLRGPAAGAHLYCPVRLPDALLAASARAPGPHLPNRPETLLA", "length": 384 }, "evidence": [ { "id": "A0A8V0YLB3", "url": "https://omabrowser.org/oma/group/A0A8V0YLB3/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1RXP2-1", "protein_name": "Forkhead box Q1", "gene_name": "FOXQ1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MKLEVFGPRAALGDKPGSDVEGAGGSDAPSPLSAAGDDSLGSDGDCAANSPAAAGGGAGTLAGGGERSAGGGPGAQEAGAAAAAAAAAPEAGAAGPSEGGAGGGEGARGKPYTRRPKPPYSYIALIAMAIRDSAGGRLTLAEINEYLMGKFPFFRGSYTGWRNSVRHNLSLNDCFVKVLRDPSRPWGKDNYWMLNPNSEYTFADGVFRRRRKRLGHRTALPGPGPRPSDAAAPPSPSPAASAPGPASPRARSPARPEGRASPAGRFSGPFAIDSILSKPFRSRRTGDAGPGPRLPWGAAPCPPLPAFPALLPGAPGGALLPLCAYGAAEPPRLGARGAEAPPLLLAPLAAPAPAKPLRGPAGGAHLYCPVRLPDAPHAASARAPGQHLPCALETLLA", "length": 397 }, "evidence": [ { "id": "A0A8V0YLB3", "url": "https://omabrowser.org/oma/group/A0A8V0YLB3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "O70220-1", "protein_name": "Forkhead box protein Q1", "gene_name": "Foxq1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKLEVFVPRAAHGDKMGSDLEGAGSSDVPSPLSAAGDDSLGSDGDCAANSPAAGSGAGDLEGGGGERNSSGGPSAQDGPEATDDSRTQASAAGPCAGGVGGGEGARSKPYTRRPKPPYSYIALIAMAIRDSAGGRLTLAEINEYLMGKFPFFRGSYTGWRNSVRHNLSLNDCFVKVLRDPSRPWGKDNYWMLNPNSEYTFADGVFRRRRKRLSHRTTVSASGLRPEEAPPGPAGTPQPAPAARSSPIARSPARQEERSSPASKFSSSFAIDSILSKPFRSRRDGDSALGVQLPWGAAPCPPLRAYPALLPAAPGGALLPLCAYGASEPTLLASRGTEVQPAAPLLLAPLSTAAPAKPFRGPETAGAAHLYCPLRLPTALQAAAACGPGPHLSYPVETLLA", "length": 400 }, "evidence": [ { "id": "A0A8V0YLB3", "url": "https://omabrowser.org/oma/group/A0A8V0YLB3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q63244-1", "protein_name": "Forkhead box protein Q1", "gene_name": "Foxq1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKLEVFAPRAAHGDKMGSDLEGAGSSDVPSPLSAAGDDSLGSDGDCAANSPAAGSGAGDLEGGGGERNSSGGASTQDDPEVTDGSRTQASPVGPCAGSVGGGEGARSKPYTRRPKPPYSYIALIAMAIRDSAGGRLTLAEINEYLMGKFPFFRGSYTGWRNSVRHNLSLNDCFVKVLRDPSRPWGKDNYWMLNPNSEYTFADGVFRRRRKRLSHRTTVSASGYGGGSPPGPAGTPQPAPTAGSSPIARSPARQEEGSSPASKFSSSFAIDSILSKPFRSRRDGTPALGVQLPWSAAPCPPLRAYPALLPASSGGALLPLCAYGAAEPTLLASRGAEVQPAAPLFVAPLSTAAPAKPFRGPETAGAAHLYCPLRLPTALQAAAACGPGPHLSYRVETLLA", "length": 399 }, "evidence": [ { "id": "A0A8V0YLB3", "url": "https://omabrowser.org/oma/group/A0A8V0YLB3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9C009-1", "protein_name": "Forkhead box protein Q1", "gene_name": "FOXQ1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKLEVFVPRAAHGDKQGSDLEGAGGSDAPSPLSAAGDDSLGSDGDCAANSPAAGGGARDTQGDGEQSAGGGPGAEEAIPAAAAAAVVAEGAEAGAAGPGAGGAGSGEGARSKPYTRRPKPPYSYIALIAMAIRDSAGGRLTLAEINEYLMGKFPFFRGSYTGWRNSVRHNLSLNDCFVKVLRDPSRPWGKDNYWMLNPNSEYTFADGVFRRRRKRLSHRAPVPAPGLRPEEAPGLPAAPPPAPAAPASPRMRSPARQEERASPAGKFSSSFAIDSILRKPFRSRRLRDTAPGTTLQWGAAPCPPLPAFPALLPAAPCRALLPLCAYGAGEPARLGAREAEVPPTAPPLLLAPLPAAAPAKPLRGPAAGGAHLYCPLRLPAALQAASVRRPGPHLPYPVETLLA", "length": 403 }, "evidence": [ { "id": "A0A8V0YLB3", "url": "https://omabrowser.org/oma/group/A0A8V0YLB3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLB3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLB3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLB3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLB3" } ], "pmid": "" }, { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLB3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLB3" } ], "pmid": "" }, { "name": "anatomical structure morphogenesis", "id": "GO:0009653", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009653", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLB3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLB3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "DNA-binding transcription repressor activity, RNA polymerase II-specific", "id": "GO:0001227", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001227", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLB3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLB3" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLB3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLB3" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLB3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLB3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 137, "end_pos": 139, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YLB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLB3" }, { "id": "PS50039", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50039" }, { "id": "PRU00089", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00089" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Fork-head", "eco_id": "ECO_0000259", "start_pos": 86, "end_pos": 181, "start_aa": "Lys", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 60, 73, 365 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 137, "end_pos": 139 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 3 }, { "field": "total_sites", "count": 3 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 3 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 3 }, { "field": "exact_o_linked_sites", "count": 3 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 3 }, { "field": "total_sites", "count": 3 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 3 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 3 }, { "field": "exact_o_linked_sites", "count": 3 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YLB7-1", "uniprot_ac": "A0A8V0YLB7", "uniprot_id": "A0A8V0YLB7_CHICK", "mass": { "chemical_mass": 31821.0, "monoisotopic_mass": 31821.0 }, "refseq": {}, "gene_names": [ { "name": "SREK1IP1", "type": "recommended", "evidence": [ { "id": "A0A8V0YLB7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLB7" } ] } ], "protein_names": [ { "name": "SREK1 interacting protein 1", "type": "synonym", "evidence": [ { "id": "A0A8V0YLB7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLB7/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLB7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLB7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SREK1IP1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLB7", "locus": {} } ], "crossref": [ { "id": "IPR000477", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000477", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YLB7", "url": "https://www.orthodb.org/?gene=A0A8V0YLB7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR33332", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR33332", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00078", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00078", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YLB7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLB7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLB7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLB7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVPHHILLSKLERCGFEGWTVQWIRNWLSGCSRRVVINGSVSGWRPVRSGIPQWSVLGPVLFNIFIRDTNGGIECTLSKFADDTELSGAVDTLEGREAIQRDLDMLEKWAHENLMKFNKAKCRVLHLGWGNCRCFYNLGEDLIESSPAEKDLGVLMDEKLDVSQQCALAAQKANCVLGCIKKEVASREREVIVPLYSALVRPHLEYSVQVWGPQYKKDTDLLEQVQRRATKMIRGLEHLSYQESLRELGLFSLEKRRFWGDLMVAFQYLKGAYKQEGE", "length": 278, "header": "tr|A0A8V0YLB7-1|A0A8V0YLB7_CHICK Isoform 1 of SREK1 interacting protein 1 OS=Gallus gallus OX=9031 GN=SREK1IP1 PE=4 SV=1 CANONICAL=A0A8V0YLB7-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YLB7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLB7/entry#A0A8V0YLB7-1", "sequence": { "sequence": "MVPHHILLSKLERCGFEGWTVQWIRNWLSGCSRRVVINGSVSGWRPVRSGIPQWSVLGPVLFNIFIRDTNGGIECTLSKFADDTELSGAVDTLEGREAIQRDLDMLEKWAHENLMKFNKAKCRVLHLGWGNCRCFYNLGEDLIESSPAEKDLGVLMDEKLDVSQQCALAAQKANCVLGCIKKEVASREREVIVPLYSALVRPHLEYSVQVWGPQYKKDTDLLEQVQRRATKMIRGLEHLSYQESLRELGLFSLEKRRFWGDLMVAFQYLKGAYKQEGE", "length": 278, "header": "tr|A0A8V0YLB7-1|A0A8V0YLB7_CHICK Isoform 1 of SREK1 interacting protein 1 OS=Gallus gallus OX=9031 GN=SREK1IP1 PE=4 SV=1 CANONICAL=A0A8V0YLB7-1" }, "locus": { "chromosome": "Z", "start_pos": 20751954, "end_pos": 20751121, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029124.1", "url": "https://www.ensembl.org/id/ENSGALT00010029124.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016882.1", "url": "https://www.ensembl.org/id/ENSGALP00010016882.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 38, "end_pos": 40, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YLB7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLB7" }, { "id": "PF00078", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00078" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Reverse transcriptase", "eco_id": "ECO_0000259", "start_pos": 2, "end_pos": 131, "start_aa": "Val", "end_aa": "Asn", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 38, "end_pos": 40 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YLB9-1", "uniprot_ac": "A0A8V0YLB9", "uniprot_id": "A0A8V0YLB9_CHICK", "mass": { "chemical_mass": 351624.0, "monoisotopic_mass": 351624.0 }, "refseq": {}, "gene_names": [ { "name": "CPLANE1", "type": "recommended", "evidence": [ { "id": "A0A8V0YLB9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLB9" } ] } ], "protein_names": [ { "name": "Ciliosis and planar polarity effector complex subunit 1", "type": "synonym", "evidence": [ { "id": "A0A8V0YLB9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLB9/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLB9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLB9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CPLANE1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLB9", "locus": { "chromosome": "Z", "start_pos": 12019508, "end_pos": 12083480, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013777", "url": "https://www.ensembl.org/id/ENSGALG00010013777" } ] } } ], "crossref": [ { "id": "IPR028236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YLB9", "url": "https://www.orthodb.org/?gene=A0A8V0YLB9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14492", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14492", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14492:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14492:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15392", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15392", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YLB9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLB9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLB9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLB9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRMEVKLDVLVSTSIKQRKPWTRITWIGQEKEAVFLLDDKHINEINLASGKTKKKIPQLQSLLKNVVVLTTSINGAWLAGLLTTGELFLWNKDQDCLKLIPAIEEARKVVAVAQECLMRLYLYVSEDGRRALLTTPTACVFLWESTEYENTLSYKNFSGRWTQILPSESVTLPSTEEKEVGVHATFLQNEVLGDCCLCSFVFYSGECLLLTFLILRWHENGFKYASSLPYQIHWVQQTCSLVNLVPQCVSIKSRGALLSAFARDGLFLAVAVNQIDPKATQILFLNTLNFLTVSGSVKGCSSKSSTIPSKFIRSYWVGDMSWTPDSLFLACMLKRGSLILLTGMGELLTLITSGCSVEFGPAEFIPIHPLITYRQHNSLCQDSSQTLGSSASESDLMRQRFSVASHSRLPYLIVSDGFMITVLRFHNNVSPVGFLRSLLLDSTQRLENIRRNVMNSQSKGRHLCLRSLLSLKDSLLKHTQNHTSFFFNVPKFLEEDTTETNQKTTDLLDYEDESDDEKLFHNSSSSLFSQRVHSFVDKADQGHIEFASMFDTIHAKDNTEEKDKLPAELNSVQRSLLTAWQIGISKNIEERDTFLNYTISCITHYFNILQFVECSSLNQDAFLNKSVKNSHWIHCVLKYFQLCLSVLHWHSRAGMTGHVAKLTLQTLKLMLVQKQDQLFSKNLLACFCLLKMVSHTLSSTCIPQYENLFASPGVNSLVELDSFIVPIFLFLDESATQEFSSLKSLLRELPQALNCDEKTEKRLIVLWRFLYKRVVSYWIQLNKNAYKNTEEETVVSLLLSHIQATLQSSGVLLEQHFKINSIAGEEKFLLGSYRESVDVWKRCLCEIKAKGGRRACFLQSRYYLAILFCHLYHYNLCEAQGLCDHLVGEILRRSQLSVSQMENFSDTKYSQHELWMITNVHTETAMAVIRSMARFMAAYFTNQLLYIFPPHSVDILHPLHIKPDVSPRIIPLQRHLVTRAVRDQNLSSVWTVEYALDLFFVGGLMPEAVWLTHRLGDWKLSVSIGVAYALYCQNSDEFTRLKITEHHLPLNLSPVQTFQEKLQSLLGQPATSETTTEEYIKYKQFTDPIEEEDADVLYSSVQELLKAAVMADADILSETFQLLIDSVKDLSRKFCGLIPDGLYLPAPPLYCPQPASLSEEDCNDIALKTERENRQKVSGVLQRIILLFRATCCSFPAAQWYISQLKWGRKIMQKIRMKGSLPSLSPFPETLLRYCNFHTAFWSESTSSGDHQLDDISCKILGWFRELCALCWMFHVRERLSDSCRRYQAARENANSHKDLKKNEYDASTVEHCLNAAEWACRMLPFCRFMNVEELIQDVILSLLGELPPVKKVAEIFVKAFPNPEDVRVPLKDKYHSLQQRFRHCTVQGPESEETMSVVIQAMEKARMKNLRLVIRNIGPIEINVWEPAEEGADYQEEHCYDNVSLGTSISRSTLTDLGNPQLHSEAETVDTLSDALLAEETRVQTPLPQREKEYQRQGEIGSKNATCKTRALSWKTEHMEKACRKDTQNQCNLPIVGAWEFERDDEEYVNFLELFLSYVLERDLVKYSDLRIPFLTSFSGLLRKHELNSLFFDIHTTLKRRQAKTRSRSVFRAGSCYTVTLTSYNPETVSVHSVNQNVLENPNIVQSTVKTTEPSVHNSIKELKEGLFGLKRKSIYRAQSDSQGVTVASPSQTVPKDASCTLQTLETAKYVYKTTHFPDTVPGEELAIELTGKFSNIGRLLEWMIRWSDRRLLRGSKKQDSIDESLPMMHVKTSAAAVLTSLWLLEQLCKDGTQARSVTFKNPSNQCLKESTSLSEAQPRTKRECGVDEGTSANPPADVHSIQAYDYLCENSLGISTKSKYFDKKEIKHGNCYLPHVTEDLNKVEPFLQEELDITSESEEFFEEPFETPKSSNSSVRIKPGKDISSSAVDSPQGDQTVKKAKERKAEQNVVTEVATSTISQSFSLEQNSEVPSNIEISVSHGQPSLAAVSSISSVISSTSICAKKEDINKEVPTEEKLNTSETVRQMLQDEMFKLVQLQQINFMSLMQIVQSSFANLPNVQQTLQQYQSAHLEGIQPVPPAEGNGSGRPSCSAGASLKTQLPTGDNRGKYDQKSSDFQPTNSLRDEGNDVHIENHQNVSLSLLESHNRETGFMPSSQDLHSSAPVKPFHLLAPSSDVQKAPKFIPVEKNTNFSDGFPLLKLESGYHSKPAFLHPIEMSSAFARPPPIPRVAWNSSDSLWNHQSSYKERRSKSTAHLNMSRYKPEISRKMQEEEKRWAETVHKPPSKHRCSGQYEEREVSLEEQFSGNVKMDSTVTTSNVAGIPLLHLNLDPVSKLPPVIRQTISTALIPVKPVTKETDCRETLQHTGISLLHANLPQQKKVPKFIPPQDLIAFEQYCYHHTVASTSFGQDQTKPIQLLKTDLKPFEPRGVQNSTKRQKRRDRKQMKEELEKEKRSVSFCPDDSIINISDTVMAVEPKTDPETKCTSYLQDNSFISMDKAAEAVTTPDLHYMASTSKKIAETQDASTNTHPVPKSYKDIGISTEIEISDLGKNESDMSVPVSESSSVPKLSSPDMYLNLRFSSEVKERILPSTLSDVPDLSEHKYVSVTDIEDNDILNDLPMIPESADEIVTTEQNEKFEIPSTAELHHVAASVTNAIPSELLLKKDNHLKDVSSQKQKEHTETGSPRESVTWDIELEDARAFPSTRLMSKVIDKEYLSTKHQEIDMQLRMLQSITKNMEEDFRNTRQLVQIIEDLEMDANSDSHDPLSFSEDSRVMDDGFHLNGKLSESSVEDPLQITGLSDVTDIIRNLVTEGGISPMELGFPKTQAKKFSRYSQKTEKEKKEIRAWMKRKQKERMREYMKKVDEQRQKEHNPFNFKKYTHCRLTSKDIQLLKKKKEEKDKRLYAEHHRMRVSQALSLMNEMLSESVMLPASEHRPWSRARSPQECRKHHIVSTKGGHPNNRVMSERSRTAVRPRFGQKGHHFTPALGSAQSKAAEYRMSRVSEQKYPAVSTAFETEGFDHETGRDVESPWTVPDDIQRLLEDSHDTLFQDSAPLSFSPVVNHETDRISESTGSILSRLDWNAIEAMIADVEDT", "length": 3096, "header": "tr|A0A8V0YLB9-1|A0A8V0YLB9_CHICK Isoform 1 of Ciliosis and planar polarity effector complex subunit 1 OS=Gallus gallus OX=9031 GN=CPLANE1 PE=4 SV=1 CANONICAL=A0A8V0YLB9-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YLB9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLB9/entry#A0A8V0YLB9-1", "sequence": { "sequence": "MRMEVKLDVLVSTSIKQRKPWTRITWIGQEKEAVFLLDDKHINEINLASGKTKKKIPQLQSLLKNVVVLTTSINGAWLAGLLTTGELFLWNKDQDCLKLIPAIEEARKVVAVAQECLMRLYLYVSEDGRRALLTTPTACVFLWESTEYENTLSYKNFSGRWTQILPSESVTLPSTEEKEVGVHATFLQNEVLGDCCLCSFVFYSGECLLLTFLILRWHENGFKYASSLPYQIHWVQQTCSLVNLVPQCVSIKSRGALLSAFARDGLFLAVAVNQIDPKATQILFLNTLNFLTVSGSVKGCSSKSSTIPSKFIRSYWVGDMSWTPDSLFLACMLKRGSLILLTGMGELLTLITSGCSVEFGPAEFIPIHPLITYRQHNSLCQDSSQTLGSSASESDLMRQRFSVASHSRLPYLIVSDGFMITVLRFHNNVSPVGFLRSLLLDSTQRLENIRRNVMNSQSKGRHLCLRSLLSLKDSLLKHTQNHTSFFFNVPKFLEEDTTETNQKTTDLLDYEDESDDEKLFHNSSSSLFSQRVHSFVDKADQGHIEFASMFDTIHAKDNTEEKDKLPAELNSVQRSLLTAWQIGISKNIEERDTFLNYTISCITHYFNILQFVECSSLNQDAFLNKSVKNSHWIHCVLKYFQLCLSVLHWHSRAGMTGHVAKLTLQTLKLMLVQKQDQLFSKNLLACFCLLKMVSHTLSSTCIPQYENLFASPGVNSLVELDSFIVPIFLFLDESATQEFSSLKSLLRELPQALNCDEKTEKRLIVLWRFLYKRVVSYWIQLNKNAYKNTEEETVVSLLLSHIQATLQSSGVLLEQHFKINSIAGEEKFLLGSYRESVDVWKRCLCEIKAKGGRRACFLQSRYYLAILFCHLYHYNLCEAQGLCDHLVGEILRRSQLSVSQMENFSDTKYSQHELWMITNVHTETAMAVIRSMARFMAAYFTNQLLYIFPPHSVDILHPLHIKPDVSPRIIPLQRHLVTRAVRDQNLSSVWTVEYALDLFFVGGLMPEAVWLTHRLGDWKLSVSIGVAYALYCQNSDEFTRLKITEHHLPLNLSPVQTFQEKLQSLLGQPATSETTTEEYIKYKQFTDPIEEEDADVLYSSVQELLKAAVMADADILSETFQLLIDSVKDLSRKFCGLIPDGLYLPAPPLYCPQPASLSEEDCNDIALKTERENRQKVSGVLQRIILLFRATCCSFPAAQWYISQLKWGRKIMQKIRMKGSLPSLSPFPETLLRYCNFHTAFWSESTSSGDHQLDDISCKILGWFRELCALCWMFHVRERLSDSCRRYQAARENANSHKDLKKNEYDASTVEHCLNAAEWACRMLPFCRFMNVEELIQDVILSLLGELPPVKKVAEIFVKAFPNPEDVRVPLKDKYHSLQQRFRHCTVQGPESEETMSVVIQAMEKARMKNLRLVIRNIGPIEINVWEPAEEGADYQEEHCYDNVSLGTSISRSTLTDLGNPQLHSEAETVDTLSDALLAEETRVQTPLPQREKEYQRQGEIGSKNATCKTRALSWKTEHMEKACRKDTQNQCNLPIVGAWEFERDDEEYVNFLELFLSYVLERDLVKYSDLRIPFLTSFSGLLRKHELNSLFFDIHTTLKRRQAKTRSRSVFRAGSCYTVTLTSYNPETVSVHSVNQNVLENPNIVQSTVKTTEPSVHNSIKELKEGLFGLKRKSIYRAQSDSQGVTVASPSQTVPKDASCTLQTLETAKYVYKTTHFPDTVPGEELAIELTGKFSNIGRLLEWMIRWSDRRLLRGSKKQDSIDESLPMMHVKTSAAAVLTSLWLLEQLCKDGTQARSVTFKNPSNQCLKESTSLSEAQPRTKRECGVDEGTSANPPADVHSIQAYDYLCENSLGISTKSKYFDKKEIKHGNCYLPHVTEDLNKVEPFLQEELDITSESEEFFEEPFETPKSSNSSVRIKPGKDISSSAVDSPQGDQTVKKAKERKAEQNVVTEVATSTISQSFSLEQNSEVPSNIEISVSHGQPSLAAVSSISSVISSTSICAKKEDINKEVPTEEKLNTSETVRQMLQDEMFKLVQLQQINFMSLMQIVQSSFANLPNVQQTLQQYQSAHLEGIQPVPPAEGNGSGRPSCSAGASLKTQLPTGDNRGKYDQKSSDFQPTNSLRDEGNDVHIENHQNVSLSLLESHNRETGFMPSSQDLHSSAPVKPFHLLAPSSDVQKAPKFIPVEKNTNFSDGFPLLKLESGYHSKPAFLHPIEMSSAFARPPPIPRVAWNSSDSLWNHQSSYKERRSKSTAHLNMSRYKPEISRKMQEEEKRWAETVHKPPSKHRCSGQYEEREVSLEEQFSGNVKMDSTVTTSNVAGIPLLHLNLDPVSKLPPVIRQTISTALIPVKPVTKETDCRETLQHTGISLLHANLPQQKKVPKFIPPQDLIAFEQYCYHHTVASTSFGQDQTKPIQLLKTDLKPFEPRGVQNSTKRQKRRDRKQMKEELEKEKRSVSFCPDDSIINISDTVMAVEPKTDPETKCTSYLQDNSFISMDKAAEAVTTPDLHYMASTSKKIAETQDASTNTHPVPKSYKDIGISTEIEISDLGKNESDMSVPVSESSSVPKLSSPDMYLNLRFSSEVKERILPSTLSDVPDLSEHKYVSVTDIEDNDILNDLPMIPESADEIVTTEQNEKFEIPSTAELHHVAASVTNAIPSELLLKKDNHLKDVSSQKQKEHTETGSPRESVTWDIELEDARAFPSTRLMSKVIDKEYLSTKHQEIDMQLRMLQSITKNMEEDFRNTRQLVQIIEDLEMDANSDSHDPLSFSEDSRVMDDGFHLNGKLSESSVEDPLQITGLSDVTDIIRNLVTEGGISPMELGFPKTQAKKFSRYSQKTEKEKKEIRAWMKRKQKERMREYMKKVDEQRQKEHNPFNFKKYTHCRLTSKDIQLLKKKKEEKDKRLYAEHHRMRVSQALSLMNEMLSESVMLPASEHRPWSRARSPQECRKHHIVSTKGGHPNNRVMSERSRTAVRPRFGQKGHHFTPALGSAQSKAAEYRMSRVSEQKYPAVSTAFETEGFDHETGRDVESPWTVPDDIQRLLEDSHDTLFQDSAPLSFSPVVNHETDRISESTGSILSRLDWNAIEAMIADVEDT", "length": 3096, "header": "tr|A0A8V0YLB9-1|A0A8V0YLB9_CHICK Isoform 1 of Ciliosis and planar polarity effector complex subunit 1 OS=Gallus gallus OX=9031 GN=CPLANE1 PE=4 SV=1 CANONICAL=A0A8V0YLB9-1" }, "locus": { "chromosome": "Z", "start_pos": 12083083, "end_pos": 12019942, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033090.1", "url": "https://www.ensembl.org/id/ENSGALT00010033090.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019565.1", "url": "https://www.ensembl.org/id/ENSGALP00010019565.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "cilium assembly", "id": "GO:0060271", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060271", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLB9", "url": 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] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036869", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036869", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051964", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051964", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR054076", "url": "https://www.ebi.ac.uk/interpro/entry/IPR054076", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "RANHEES", "url": "https://omabrowser.org/oma/group/RANHEES/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YLC8", "url": "https://www.orthodb.org/?gene=A0A8V0YLC8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR44029", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR44029", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR44029:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR44029:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00226", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00226", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12171", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12171", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21884", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21884", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_425006", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_425006", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YLC8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLC8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLC8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLC8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRCHYEVLGVRRDAAEEELKRAYRRLALRWHPDKNLENAEEAAEQFKLIQAAYDVLSDPQERAWYDNHREALLRGVNGDYQDDSLDLLRYFTVSCYSGYGDDEKGFFTVYRHVFEQIAKEEMEYITHEDIEEFPTFGYSHSDYDTIVHPFYAYWQSFCTQKNFAWKEEYDTRQASNRWEKRAMEKENKKTRDKAKKERNELVRQLVAFIRKRDRRVQAHRKLVEEQNAEKLRKAEEIRRQQKLKQAKLAEQYKEQSWITMSDLEKELKEMEAQYEKEFGDGSDAEVELEGQETKEGTEDKLNDVAEEAEYADDLYCPACDKLLKTEKAMKNHEKSKKHREMVALLRQQLEEEEEKFPASSDDVNGMHTKEEEETGEVSKQKLSKKQKRKQKTMMTYEDSFDKSADEETIEQKELPCVDKDSGPTEQSADDDQRCAVSEEASATEDGSQVNEAHSEVKSSTKPKGKKAKDAKKSAKGSSEHQTMNEVPIHCVTCNCTFPSRNKLFEHLKATGHAKATQAPSVNGAVHTRSKKEKRKNR", "length": 537, "header": "tr|A0A8V0YLC8-1|A0A8V0YLC8_CHICK Isoform 1 of DnaJ homolog subfamily C member 21 OS=Gallus gallus OX=9031 GN=DNAJC21 PE=4 SV=1 CANONICAL=A0A8V0YLC8-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YLC8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLC8/entry#A0A8V0YLC8-1", "sequence": { "sequence": "MRCHYEVLGVRRDAAEEELKRAYRRLALRWHPDKNLENAEEAAEQFKLIQAAYDVLSDPQERAWYDNHREALLRGVNGDYQDDSLDLLRYFTVSCYSGYGDDEKGFFTVYRHVFEQIAKEEMEYITHEDIEEFPTFGYSHSDYDTIVHPFYAYWQSFCTQKNFAWKEEYDTRQASNRWEKRAMEKENKKTRDKAKKERNELVRQLVAFIRKRDRRVQAHRKLVEEQNAEKLRKAEEIRRQQKLKQAKLAEQYKEQSWITMSDLEKELKEMEAQYEKEFGDGSDAEVELEGQETKEGTEDKLNDVAEEAEYADDLYCPACDKLLKTEKAMKNHEKSKKHREMVALLRQQLEEEEEKFPASSDDVNGMHTKEEEETGEVSKQKLSKKQKRKQKTMMTYEDSFDKSADEETIEQKELPCVDKDSGPTEQSADDDQRCAVSEEASATEDGSQVNEAHSEVKSSTKPKGKKAKDAKKSAKGSSEHQTMNEVPIHCVTCNCTFPSRNKLFEHLKATGHAKATQAPSVNGAVHTRSKKEKRKNR", "length": 537, "header": "tr|A0A8V0YLC8-1|A0A8V0YLC8_CHICK Isoform 1 of DnaJ homolog subfamily C member 21 OS=Gallus gallus OX=9031 GN=DNAJC21 PE=4 SV=1 CANONICAL=A0A8V0YLC8-1" }, "locus": { "chromosome": "Z", "start_pos": 11138020, "end_pos": 11123965, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031882.1", "url": "https://www.ensembl.org/id/ENSGALT00010031882.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018685.1", "url": "https://www.ensembl.org/id/ENSGALP00010018685.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2QC19-1", "protein_name": "DnaJ homolog subfamily C member 21", "gene_name": "Dnajc21", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRSRRRRPLRASACRSPRCPPPRASSVPRRCRRRRRARWLAGCWRRAPTGGEDSQRRRCRFCPGPGVGPAPGPGPVSSPAMKCHYEALGVRRDASEEELKKAYRKLALRWHPDKNLDNAAEAAEQFKLIQAAYDVLSDPQERAWYDNHREALLKGGLDGEYQDDSLDLLHYFTVTCYSGYGDDEKGFYAVYRDVFALIAKEELECMSEGGAEDFPTFGDSQSDYDTVVHPFYAYWQSFCTQKNFAWKEEYDTRQASNRWEKRAMEKENKKIRDKARKEKNELVRQLVAFIRKRDKRVQAHRKLVEEQNAEKARKAEEMRRQQKLKQAKLAEQYREQSWMTMANLEKELREMEARYEKEFGDGSDENEVEEQEAKDAVDGKDSEEAEETELYGDLYCPACDKSFKTEKAMKNHEKSKKHREMVALLKQQLEEEEEQFSGAQMDENLLNANSEEETEDIPRQKRSKKQKKRKQKSVQNFDDNFNENGTEEGGKIDPKETKSNEDNAKELENRPQENICITETTEACEDPKSEAKSVPKSKGKKTKDVKKSVKVPAEPQPVSDVLISCATCHSEFPSRNKLFDHLKATGHARAPSAAASLDSVSSSRNKKEKRRNR", "length": 613 }, "evidence": [ { "id": "A0A8V0YLC8", "url": "https://omabrowser.org/oma/group/A0A8V0YLC8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A452DIP3-1", "protein_name": "DnaJ homolog subfamily C member 21", "gene_name": "DNAJC21", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MRSRRRRRPLRAPACRNQRRLSPPRAAVAPSRRRCRRARWLARCGRRAPAAGEDHQGRRHHFGPGPGSGPAPGPGPGPSPLPCRAMKCHYEALGVRRDASEEELKKAYRKLALKWHPDKNLDNAAEAAEQFKLIQAAYDVLSDPQERAWYDNHREALLKGGLDGEYQDDSLDLLHYFTVTCYSGYGDDEKGFYTVYRNVFEMIAKEELESALEEDMEDFPTFGDSQSDYDTVVHPFYAYWQSFCTQKNFAWKEEYDTRQASNRWEKRAMEKENKKIRDKARKEKNELVRQLVAFIRKRDRRVQAHRKLVEEQNAEKARKAEAMRRQQKLKQAKLAEQYREQSWMAVADLEKELREMEAQYEKQFGDGSGEDEAEDQELRDGQDGKDSDEAEDAELYDGLYCPACDKSFKTEKAMRNHEKSKKHREMVALLKQQLEEEEANFSGPQTDENSLNANSEEEMEDAPKQKLSRKQKKKKQKPAQNYDDNFNENGIGEGVKIDPEDTNLNQNSAKESEDSLQENVGVTETVELCDDPKTEAKSVSKPKGKKAKDTKKSVRVPAEPQTMSDVLISCTTCHSEFPSRNKLFDHLKATGHARAPSSSTSLNSVTNSRNKKEKRKNR", "length": 618 }, "evidence": [ { "id": "A0A8V0YLC8", "url": "https://omabrowser.org/oma/group/A0A8V0YLC8/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "E9Q8D0-1", "protein_name": "DnaJ homolog subfamily C member 21", "gene_name": "Dnajc21", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKCHYEALGVRRDASEEELKKAYRKLALRWHPDKNLDNAAEAAEQFKLIQAAYDVLSDPQERAWYDNHREALLKGGLDGEYQDDSLDLLHYFTVTCYSGYGDDERGFYAVYRVVFELIAKEELECMSEGDVEDFPTFGDSQSDYDTVVHPFYAHWQSFCTQKNFSWKEEYDTRQASNRWEKRAMEKENKKIRDRARKEKNELVRQLVAFIRKRDKRVQAHRKLVEEQNAEKARKAEEMRRQQKLKQAKLAEQYREQSWMTMANLEKELQEMEARYEKEFGDGSDENEVEDQEPRNGLDGKDSEEAEEAELYQDLYCPACDKSFKTEKAMKNHEKSKKHREMVALLKQQLEEEEEQFSGVQMDENVLNANSEEEMEDTPKQKLSKKQKKKKQKSAQNFDDNFNENGTEEGGKIAPEKTKSNEDNAKELENRPQENTCITETTEACEDPKSEAKSVPKSKGKKTKDVKKSVKAPAEAQPVSDVLISCATCHSEFPSRNKLFDHLKATGHARAPSATASLNSVTRNKKEKRRSR", "length": 531 }, "evidence": [ { "id": "A0A8V0YLC8", "url": "https://omabrowser.org/oma/group/A0A8V0YLC8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P53863-1", "protein_name": "J protein JJJ1", "gene_name": "JJJ1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MKTCYYELLGVETHASDLELKKAYRKKALQYHPDKNPDNVEEATQKFAVIRAAYEVLSDPQERAWYDSHKEQILNDTPPSTDDYYDYEVDATVTGVTTDELLLFFNSALYTKIDNSAAGIYQIAGKIFAKLAKDEILSGKRLGKFSEYQDDVFEQDINSIGYLKACDNFINKTDKLLYPLFGYSPTDYEYLKHFYKTWSAFNTLKSFSWKDEYMYSKNYDRRTKREVNRRNEKARQQARNEYNKTVKRFVVFIKKLDKRMKEGAKIAEEQRKLKEQQRKNELNNRRKFGNDNNDEEKFHLQSWQTVKEENWDELEKVYDNFGEFENSKNDKEGEVLIYECFICNKTFKSEKQLKNHINTKLHKKNMEEIRKEMEEENITLGLDNLSDLEKFDSADESVKEKEDIDLQALQAELAEIERKLAESSSEDESEDDNLNIEMDIEVEDVSSDENVHVNTKNKKKRKKKKKAKVDTETEESESFDDTKDKRSNELDDLLASLGDKGLQTDDDEDWSTKAKKKKGKQPKKNSKSTKSTPSLSTLPSSMSPTSAIEVCTTCGESFDSRNKLFNHVKIAGHAAVKNVVKRKKVKTKRI", "length": 590 }, "evidence": [ { "id": "A0A8V0YLC8", "url": "https://omabrowser.org/oma/group/A0A8V0YLC8/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q5F1R6-1", "protein_name": "DnaJ homolog subfamily C member 21", "gene_name": "DNAJC21", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKCHYEALGVRRDASEEELKKAYRKLALKWHPDKNLDNAAEAAEQFKLIQAAYDVLSDPQERAWYDNHREALLKGGFDGEYQDDSLDLLRYFTVTCYSGYGDDEKGFYTVYRNVFEMIAKEELESVLEEEVDDFPTFGDSQSDYDTVVHPFYAYWQSFCTQKNFAWKEEYDTRQASNRWEKRAMEKENKKIRDKARKEKNELVRQLVAFIRKRDKRVQAHRKLVEEQNAEKARKAEEMRRQQKLKQAKLVEQYREQSWMTMANLEKELQEMEARYEKEFGDGSDENEMEEHELKDEEDGKDSDEAEDAELYDDLYCPACDKSFKTEKAMKNHEKSKKHREMVALLKQQLEEEEENFSRPQIDENPLDDNSEEEMEDAPKQKLSKKQKKKKQKPAQNYDDNFNVNGPGEGVKVDPEDTNLNQDSAKELEDSPQENVSVTEIIKPCDDPKSEAKSVPKPKGKKTKDMKKPVRVPAEPQTMSVLISCTTCHSEFPSRNKLFDHLKATGHARAPSSSSLNSATSSQSKKEKRKNR", "length": 531 }, "evidence": [ { "id": "A0A8V0YLC8", "url": "https://omabrowser.org/oma/group/A0A8V0YLC8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9W0X8-1", "protein_name": "DnaJ homolog subfamily C member 21", "gene_name": "BcDNA:GH03108", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MRCYYEELELQRNANDGDIKSAYRKMALRWHPDKNPDRLAEAKERFQLIQQAYEVLSDPQERSWYDNHREQILRGKNSDYAENCLDVFQFFTSSCYKGYGDNEHGFYRVYTDVFVQIASEDLEFMDKDDRLGMAPDFGHSNSSYEDVVGPFYAFWQAYSTRKTYDWLCPYDVREIKERFILRKVEKEMKKIVQAARKERNEEVRNLVNFVRKRDPRVQAYRRMLEERVEANRLKQEEKRKEQLRKRQEELAAVRKNNVFNEGYEEQLKQLEQQYDSKSEDYTDEDENDDDGEDFDHEGGQEAEEYEVEYVDDLYCVACNKTFKNAKARANHEESKKHNENVDRLCQEMEEEEDAFHNEPHEDSLMGVQESLEELQVSEDQISFDGVPSEEESSLAKRTKKNKKARKSAVKQAQAEGSDEPDEPIEKKAIKSESEDEDWSKGKKASKKSKSKKTTTRKVKLLEQTVSEPNTKEATVAPKSGDEDLDPTKSQHTCVTCRLVFDSKNKLFAHLKKTNHGVYIPKAKPNVEGKPPGKAKGKRNK", "length": 540 }, "evidence": [ { "id": "A0A8V0YLC8", "url": "https://omabrowser.org/oma/group/A0A8V0YLC8/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLC8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLC8" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLC8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLC8" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLC8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLC8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLC8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLC8" } ], "pmid": "" }, { "name": "nucleic acid binding", "id": "GO:0003676", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003676", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLC8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLC8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 494, "end_pos": 496, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YLC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLC8" }, { "id": "PS50076", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50076" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "J", "eco_id": "ECO_0000259", "start_pos": 3, "end_pos": 69, "start_aa": "Cys", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 494, "end_pos": 496 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { 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This record is derived from a genomic sequence (NC_052544.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015149558.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015149558", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015149558" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLG3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLG3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SOWAHA", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLG3", "locus": { "chromosome": "13", "start_pos": 16645991, "end_pos": 16632995, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013667", "url": "https://www.ensembl.org/id/ENSGALG00010013667" } ] } } ], "crossref": [ { "id": "A0A8V0YLG3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YLG3", "database": "AlphaFoldDB", "categories": [] }, { "id": "416334", 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"biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YLG3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLG3" }, { "id": "PF25877", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25877" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SOWAHA-C winged helix-turn-helix", "eco_id": "ECO_0000259", "start_pos": 6, "end_pos": 87, "start_aa": "Leu", "end_aa": "Asp", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 155 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YLX2-1", "uniprot_ac": "A0A8V0YLX2", "uniprot_id": "A0A8V0YLX2_CHICK", "mass": { "chemical_mass": 61781.0, "monoisotopic_mass": 61781.0 }, "refseq": { "ac": "NP_989606", "name": "interleukin-1 receptor-like 1 isoform L precursor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989606" }, "gene_names": [ { "name": "IL1RL1", "type": "recommended", "evidence": [ { "id": "A0A8V0YLX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLX2" } ] }, { "name": "IL1RL1", "type": "synonym", "evidence": [ { "id": "NP_989606", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989606" } ] }, { "name": "ST2", "type": "synonym", "evidence": [ { "id": "NP_989606", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989606" } ] } ], "protein_names": [ { "name": "Interleukin 1 receptor like 1", "type": "synonym", "evidence": [ { "id": "A0A8V0YLX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLX2/entry#names_and_taxonomy" } ] }, { "name": "interleukin-1 receptor-like 1 isoform L precursor", "type": "synonym", "evidence": [ { "id": "NP_989606", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989606" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: SRR13267655.31382.1, SRR12888513.159679.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000025.1. On Sep 23, 2021 this sequence version replaced NP_989606.1. Transcript Variant: This variant (1) represents the longest transcript and encodes the longest protein (isoform 1, also known as ST2L). Sequence Note: This RefSeq record was created from transcript and genomic sequence data from different strains because no single transcript from the same strain was available for the full length of the gene. The extent of this transcript is supported by transcript alignments and orthologous data.", "evidence": [ { "database": "RefSeq", "id": "NP_989606", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989606" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLX2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLX2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "IL1RL1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLX2", "locus": { "chromosome": "1", "start_pos": 134005547, "end_pos": 133978131, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013797", "url": "https://www.ensembl.org/id/ENSGALG00010013797" } ] } } ], "crossref": [ { "id": "A0A8V0YLX2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YLX2", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd05757", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05757", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "374136", "url": "https://www.ncbi.nlm.nih.gov/gene/374136", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000157", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000157", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003598", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003598", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004074", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004074", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013151", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013151", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015621", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015621", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035897", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035897", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:374136", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:374136", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HQSTYYI", "url": "https://omabrowser.org/oma/group/HQSTYYI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YLG5", "url": "https://www.orthodb.org/?gene=A0A8V0YLG5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YLX2", "url": "https://www.orthodb.org/?gene=A0A8V0YLX2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YNN7", "url": "https://www.orthodb.org/?gene=A0A8V0YNN7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YTP3", "url": "https://www.orthodb.org/?gene=A0A8V0YTP3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YTQ3", "url": "https://www.orthodb.org/?gene=A0A8V0YTQ3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11890", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11890", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11890:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11890:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00047", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00047", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01582", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01582", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_989606", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989606", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YLG5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLG5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLG5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLG5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLX2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLX2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLX2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLX2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YNN7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNN7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YNN7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNN7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YTP3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTP3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YTP3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTP3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YTQ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTQ3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YTQ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTQ3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MMVYVHLIFLSVFLPVSVISESYDTMEGEALVVRCPHSVLSAKVTWHHTGTRKRIPEEEEGSRVFSKGIFLWFLPTSLEDSGNYTCVINYPDGSKKERKMNVQVHPYKQGTCFPSRILYANETRKGKISCPTFRNYENATIIQWYKDCRPLQGERYFMYDPYIFIENLNKEDDGYYTCQFTYTHRGRVFNVSATRIFVSEAKHSSLPVQILFPKDEDVLEVELGAAFSLKCQARLGIKKQPIAVVTWDVNKMPAEYANEEKIRQEFSYFEGQHQEYYGEATLTISNIEHTDLQSSFSCVAMNEMGNTRTTVTLRLKKKSGPNVLMIAGFLVFLMSVAVSVVLYQSFRVDIVLLYRDLFQAYSVKDDGKIYDAYVIYPRSHSTEATFVEYFVYQIMPDILENKCGYTLCIYGRDTYPGEDKANAIEKRIQKSRRLIILLTQQLINCQELNYDQHIALYNALIQNDTKVILLEMEKMGSYENLQESLRYIIKQQGTVKWKEQHTVHPQSSNSKFWKHVRYHMPVTLRSSDSANAG", "length": 533, "header": "tr|A0A8V0YLX2-1|A0A8V0YLX2_CHICK Isoform 1 of Interleukin 1 receptor like 1 OS=Gallus gallus OX=9031 GN=IL1RL1 PE=3 SV=1 CANONICAL=A0A8V0YLX2-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YLG5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLX2/entry#A0A8V0YLG5-1", "sequence": { "sequence": "MSRRNMMVYVHLIFLSVFLPVSVISESYDTMEGEALVVRCPHSVLSAKVTWHHTGTRKRIPEEEEGSRVFSKGIFLWFLPTSLEDSGNYTCVINYPDGSKKERKMNVQVHPYKQGTCFPSRILYANETRKGKISCPTFRNYENATIIQWYKDCRPLQGERYFMYDPYIFIENLNKEDDGYYTCQFTYTHRGRVFNVSATRIFVSEAKHSSLPVQILFPKDEDVLEVELGAAFSLKCQARLGIKKQPIAVVTWDVNKMPAEYANEEKIRQEFSYFEGQHQEYYGEATLTISNIEHTDLQSSFSCVAMNEMGNTRTTVTLRLKKKCPQ", "length": 326, "header": "tr|A0A8V0YLG5-1|A0A8V0YLX2_CHICK Computationally mapped isoform of Interleukin 1 receptor like 1 OS=Gallus gallus OX=9031 GN=IL1RL1 PE=3 SV=1 CANONICAL=A0A8V0YLX2-1" }, "locus": { "chromosome": "1", "start_pos": 133992601, "end_pos": 133978234, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033164.1", "url": "https://www.ensembl.org/id/ENSGALT00010033164.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019600.1", "url": "https://www.ensembl.org/id/ENSGALP00010019600.1" } ] } }, { "isoform_ac": "A0A8V0YLX2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLX2/entry#A0A8V0YLX2-1", "sequence": { "sequence": "MMVYVHLIFLSVFLPVSVISESYDTMEGEALVVRCPHSVLSAKVTWHHTGTRKRIPEEEEGSRVFSKGIFLWFLPTSLEDSGNYTCVINYPDGSKKERKMNVQVHPYKQGTCFPSRILYANETRKGKISCPTFRNYENATIIQWYKDCRPLQGERYFMYDPYIFIENLNKEDDGYYTCQFTYTHRGRVFNVSATRIFVSEAKHSSLPVQILFPKDEDVLEVELGAAFSLKCQARLGIKKQPIAVVTWDVNKMPAEYANEEKIRQEFSYFEGQHQEYYGEATLTISNIEHTDLQSSFSCVAMNEMGNTRTTVTLRLKKKSGPNVLMIAGFLVFLMSVAVSVVLYQSFRVDIVLLYRDLFQAYSVKDDGKIYDAYVIYPRSHSTEATFVEYFVYQIMPDILENKCGYTLCIYGRDTYPGEDKANAIEKRIQKSRRLIILLTQQLINCQELNYDQHIALYNALIQNDTKVILLEMEKMGSYENLQESLRYIIKQQGTVKWKEQHTVHPQSSNSKFWKHVRYHMPVTLRSSDSANAG", "length": 533, "header": "tr|A0A8V0YLX2-1|A0A8V0YLX2_CHICK Isoform 1 of Interleukin 1 receptor like 1 OS=Gallus gallus OX=9031 GN=IL1RL1 PE=3 SV=1 CANONICAL=A0A8V0YLX2-1" }, "locus": { "chromosome": "1", "start_pos": 134003708, "end_pos": 133984566, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033183.1", "url": "https://www.ensembl.org/id/ENSGALT00010033183.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019608.1", "url": "https://www.ensembl.org/id/ENSGALP00010019608.1" } ] } }, { "isoform_ac": "A0A8V0YNN7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLX2/entry#A0A8V0YNN7-1", "sequence": { "sequence": "MMVYVHLIFLSVFLPVSVISESYDTMEGEALVVRCPHSVLSAKVTWHHTGTRKRIPEEEEGSRVFSKGIFLWFLPTSLEDSGNYTCVINYPDGSKKERKMNVQVHPYKQGTCFPSRILYANETRKGKISCPTFRNYENATIIQWYKDCRPLQGERYFMYDPYIFIENLNKEDDGYYTCQFTYTHRGRVFNVSATRIFVSEAKHSSLPVQILFPKDEDVLEVELGAAFSLKCQARLGIKKQPIAVVTWDVNKMPAEYANEEKIRQEFSYFEGQHQEYYGEATLTISNIEHTDLQSSFSCVAMNEMGNTRTTVTLRLKKKCPQ", "length": 321, "header": "tr|A0A8V0YNN7-1|A0A8V0YNN7_CHICK Computationally mapped isoform of Interleukin 1 receptor like 1 OS=Gallus gallus OX=9031 GN=IL1RL1 PE=3 SV=1 CANONICAL=A0A8V0YLX2-1" }, "locus": { "chromosome": "1", "start_pos": 133992601, "end_pos": 133984566, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033154.1", "url": "https://www.ensembl.org/id/ENSGALT00010033154.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019594.1", "url": "https://www.ensembl.org/id/ENSGALP00010019594.1" } ] } }, { "isoform_ac": "A0A8V0YTP3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLX2/entry#A0A8V0YTP3-1", "sequence": { "sequence": "MMVYVHLIFLSVFLPVSVISESYDTMEGEALVVRCPHSVLSAKVTWHHTGTRKRIPEEEEGSRVFSKGIFLWFLPTSLEDSGNYTCVINYPDGSKKERKMNVQVHPYKQGTCFPSRILYANETRKGKISCPTFRNYENATIIQWYKDCRPLQGERYFIGRVFNVSATRIFVSEAKHSSLPVQILFPKDEDVLEVELGAAFSLKCQARLGIKKQPIAVVTWDVNKMPAEYANEEKIRQEFSYFEGQHQEYYGEATLTISNIEHTDLQSSFSCVAMNEMGNTRTTVTLRLKKKCPQ", "length": 294, "header": "tr|A0A8V0YTP3-1|A0A8V0YTP3_CHICK Computationally mapped isoform of Interleukin 1 receptor like 1 OS=Gallus gallus OX=9031 GN=IL1RL1 PE=4 SV=1 CANONICAL=A0A8V0YLX2-1" }, "locus": { "chromosome": "1", "start_pos": 133992601, "end_pos": 133984566, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033146.1", "url": "https://www.ensembl.org/id/ENSGALT00010033146.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019592.1", "url": "https://www.ensembl.org/id/ENSGALP00010019592.1" } ] } }, { "isoform_ac": "A0A8V0YTQ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLX2/entry#A0A8V0YTQ3-1", "sequence": { "sequence": "MMVYVHLIFLSVFLPVSVISESYDTMEGEALVVRCPHSVLSAKVTWHHTGTRKRIPEEEEGSRVFSKGIFLWFLPTSLEDSGNYTCVINYPDGSKKERKMNVQVHPYKQGTCFPSRILYANETRKGKISCPTFRNYENATIIQWYKDCRPLQGERYFMYDPYIFIENLNKEDDGYYTCQFTYTHRGRVFNVSATRIFVSEAKHSSLPVQILFPKDEDVLEVELGAAFSLKCQARLGIKKQPIAVVTWDVNKMPAEYANEEKIRQEFSYFEGQHQEYYGEATLTISNIEHTDLQSSFSCVAMNEMGNTRTTVTLRLKKKYGKIYDAYVIYPRSHSTEATFVEYFVYQIMPDILENKCGYTLCIYGRDTYPGEDKANAIEKRIQKSRRLIILLTQQLINCQELNYDQHIALYNALIQNDTKVILLEMEKMGSYENLQESLRYIIKQQGTVKWKEQHTVHPQSSNSKFWKHVRYHMPVTLRSSDSANAG", "length": 486, "header": "tr|A0A8V0YTQ3-1|A0A8V0YTQ3_CHICK Computationally mapped isoform of Interleukin 1 receptor like 1 OS=Gallus gallus OX=9031 GN=IL1RL1 PE=3 SV=1 CANONICAL=A0A8V0YLX2-1" }, "locus": { "chromosome": "1", "start_pos": 134003708, "end_pos": 133984566, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033174.1", "url": "https://www.ensembl.org/id/ENSGALT00010033174.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019602.1", "url": "https://www.ensembl.org/id/ENSGALP00010019602.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:374136", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:374136", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2QC31-1", "protein_name": "Interleukin-1 receptor-like 1", "gene_name": "Il1rl1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MGLWALAILTVLMYFTVTKSSQPFWGLENEALIVRCPQSAGSLYPVEWYHSNTNESIPTQKRSRIFVLRDRLKFLPARVDDSGMYACVIRSPDLNTTGYMNVTIHKRPPGCSIPSYLMYSTVAGSEKNSKITCPTIGLYNWTAPVQWFKNCKPLQGPKYRAHRSYLFINDVRQEDEGDYTCKFTHTENGTNYTVTATRSFTVEEKGFSVFPVIKAPPHNRTIAVEIGKPVTITCLACFGKGSQFLMNVRWQINKRNVETFGEARIQEEKEQNQSSSNGMDCLTSVLRITDVRDKDLSLKYDCLALSHHGMIRHTVHLRRKQPINHQSTYYIVAGCSLLLMLINVLMIVLKVFWIEVALFWRDIVTPYRTQNDGKLYDAYVIYPRVFRGNSAGTSSLEYFVHHTLPDVLENKCGYKLCIYGRDLLPGQDAATVVESSIQNSRRHMFVLAPLMMHSKEFAYEQEVALHSALIQNNSKVILIEMEPLGGASPLQVGDLQDSLQHLVKMQGTIKWREDHVANKQSLSSKFWKHVRYQMPVPNRLPKTASLSDKTCLDLKQF", "length": 557 }, "evidence": [ { "id": "A0A8V0YLX2", "url": "https://omabrowser.org/oma/group/A0A8V0YLX2/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "F1MRU1-1", "protein_name": "Interleukin-1 receptor-like 1", "gene_name": "IL1RL1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MRLWVSVILTALIPSTSARFSRPFLGLENEALIVTCSRQEKYPYPVDWYYSKTNKSISTQRGNRIVASGKHLKFLPAKVSDSGFYTCIVRRPTSNKTGYVNVTIFEKQPDCNIPDYLIYSTTSGSEKNSLIFCPTINRYNWTQPVEWFKNCEVLQGPRYLVHKSFLLIDDATNKDTGHYTCKFIHNEYGVKYIVTATKSFTVTEEKGFSLPPVIKAPPQNEIKEVEIGKPINITCLACFGKGPQVMAEAFWRVNGSEVKNFGETRIQVVQEQTQSDELTCRNTVLKIEDVKEEDLTSKYDCLAMNFHGFITHTVTLRRKNPMDQQSTYYMLAGFTLLLLLINALVIILKVFWIEIILFWRDIVRPSKTRNDGKIYDAYVIYPRSCKNSPEGASSVEYFVHQILPDVLENKCGYNLCIYGRDLLPGQDVASAVESSIRMSRRHLFILTPEIVHSKEFTYEREIALHSALIQQDSKAILIEMEALCPPGGLQFEELQDSLKHLIKVQGTIKWREDHVANKRSLNSKFWKHVRYHMPQVPSRLPRKTPSLASLSAQG", "length": 554 }, "evidence": [ { "id": "A0A8V0YLX2", "url": "https://omabrowser.org/oma/group/A0A8V0YLX2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P14719-1", "protein_name": "Interleukin-1 receptor-like 1", "gene_name": "Il1rl1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MIDRQRMGLWALAILTLPMYLTVTEGSKSSWGLENEALIVRCPQRGRSTYPVEWYYSDTNESIPTQKRNRIFVSRDRLKFLPARVEDSGIYACVIRSPNLNKTGYLNVTIHKKPPSCNIPDYLMYSTVRGSDKNFKITCPTIDLYNWTAPVQWFKNCKALQEPRFRAHRSYLFIDNVTHDDEGDYTCQFTHAENGTNYIVTATRSFTVEEKGFSMFPVITNPPYNHTMEVEIGKPASIACSACFGKGSHFLADVLWQINKTVVGNFGEARIQEEEGRNESSSNDMDCLTSVLRITGVTEKDLSLEYDCLALNLHGMIRHTIRLRRKQPIDHRSIYYIVAGCSLLLMFINVLVIVLKVFWIEVALFWRDIVTPYKTRNDGKLYDAYIIYPRVFRGSAAGTHSVEYFVHHTLPDVLENKCGYKLCIYGRDLLPGQDAATVVESSIQNSRRQVFVLAPHMMHSKEFAYEQEIALHSALIQNNSKVILIEMEPLGEASRLQVGDLQDSLQHLVKIQGTIKWREDHVADKQSLSSKFWKHVRYQMPVPERASKTASVAAPLSGKACLDLKHF", "length": 567 }, "evidence": [ { "id": "A0A8V0YLX2", "url": "https://omabrowser.org/oma/group/A0A8V0YLX2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q01638-1", "protein_name": "Interleukin-1 receptor-like 1", "gene_name": "IL1RL1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGFWILAILTILMYSTAAKFSKQSWGLENEALIVRCPRQGKPSYTVDWYYSQTNKSIPTQERNRVFASGQLLKFLPAAVADSGIYTCIVRSPTFNRTGYANVTIYKKQSDCNVPDYLMYSTVSGSEKNSKIYCPTIDLYNWTAPLEWFKNCQALQGSRYRAHKSFLVIDNVMTEDAGDYTCKFIHNENGANYSVTATRSFTVKDEQGFSLFPVIGAPAQNEIKEVEIGKNANLTCSACFGKGTQFLAAVLWQLNGTKITDFGEPRIQQEEGQNQSFSNGLACLDMVLRIADVKEEDLLLQYDCLALNLHGLRRHTVRLSRKNPIDHHSIYCIIAVCSVFLMLINVLVIILKMFWIEATLLWRDIAKPYKTRNDGKLYDAYVVYPRNYKSSTDGASRVEHFVHQILPDVLENKCGYTLCIYGRDMLPGEDVVTAVETNIRKSRRHIFILTPQITHNKEFAYEQEVALHCALIQNDAKVILIEMEALSELDMLQAEALQDSLQHLMKVQGTIKWREDHIANKRSLNSKFWKHVRYQMPVPSKIPRKASSLTPLAAQKQ", "length": 556 }, "evidence": [ { "id": "A0A8V0YLX2", "url": "https://omabrowser.org/oma/group/A0A8V0YLX2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q62611-1", "protein_name": "Interleukin-1 receptor-like 1", "gene_name": "Il1rl1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MIGKWRMGLWALAILTVPMYFIVTEGRKTSWGLENEALIVRCPQRGGAINPVEWYYSNTNERIPTQKRNRIFVSRDRLKFLPAKVEDSGIYTCVIRSPESIKTGSLNVTIYKRPPNCKIPDYMMYSTVDGSDKNSKITCPTIALYNWTAPVQWFKNCKALQGPRFRAHMSYLFIDKVSHVDEGDYTCRFTHTENGTNYIVTATRSFTVEEKGFSTFPVITNPPHNYTVEVEIGKTANIACSACFGTASQFVAVLWQINKTRIGSFGKARIQEEKGPNKSSSNGMICLTSLLRITGVTDKDFSLKYDCVAMNHHGVIRHPVRLRRKQPIDHQSTYYIVAGCSLLLMFINVLVIVLKVFWIEVALFWRDIMAPYKTQNDGKLYDAYIIYPRVFRGSAAGTGSVEYFVHYTLPDVLENKCGYKLCIYGRDLLPGQDAATVVESSIQNSRRQVFVLAPHMMHSKEFAYEQEIALHSALIQNNSKVILIEMEPMGEASRLQLGDLQDSLQHLVKMQGTIKWREDHVADKQSLSSKFWKHVRYQMPVPKRPPKMASVAAPLSGKVCLDLKHF", "length": 566 }, "evidence": [ { "id": "A0A8V0YLX2", "url": "https://omabrowser.org/oma/group/A0A8V0YLX2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLX2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLX2" } ], "pmid": "" }, { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLX2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLX2" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLX2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLX2" } ], "pmid": "" }, { "name": "cell surface", "id": "GO:0009986", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009986", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLX2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLX2" } ], "pmid": "" }, { "name": "external side of plasma membrane", "id": "GO:0009897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009897", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLX2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLX2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLX2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLX2" } ], "pmid": "" }, { "name": "interleukin-1 receptor activity", "id": "GO:0004908", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004908", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLX2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLX2" } ], "pmid": "" }, { "name": "interleukin-33 binding", "id": "GO:0002113", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002113", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLX2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLX2" } ], "pmid": "" }, { "name": "interleukin-33 receptor activity", "id": "GO:0002114", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002114", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLX2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLX2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 9, "go_terms": [ { "name": "positive regulation of interleukin-5 production", "id": "GO:0032754", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032754", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLX2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLX2" } ], "pmid": "" }, { "name": "positive regulation of macrophage activation", "id": "GO:0043032", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043032", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLX2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLX2" } ], "pmid": "" }, { "name": "inflammatory response", "id": "GO:0006954", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006954", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLX2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLX2" } ], "pmid": "" }, { "name": "negative regulation of type II interferon production", "id": "GO:0032689", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032689", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLX2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLX2" } ], "pmid": "" }, { "name": "positive regulation of chemokine production", "id": "GO:0032722", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032722", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLX2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLX2" } ], "pmid": "" }, { "name": "positive regulation of inflammatory response", "id": "GO:0050729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050729", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLX2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLX2" } ], "pmid": "" }, { "name": "macrophage differentiation", "id": "GO:0030225", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030225", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLX2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLX2" } ], "pmid": "" }, { "name": "interleukin-33-mediated signaling pathway", "id": "GO:0038172", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038172", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLX2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLX2" } ], "pmid": "" }, { "name": "negative regulation of T-helper 1 type immune response", "id": "GO:0002826", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002826", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLX2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLX2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 121, "end_pos": 123, "annotation": "n_glycosylation_sequon" }, { "start_pos": 138, "end_pos": 140, "annotation": "n_glycosylation_sequon" }, { "start_pos": 190, "end_pos": 192, "annotation": "n_glycosylation_sequon" }, { "start_pos": 463, "end_pos": 465, "annotation": "n_glycosylation_sequon" }, { "start_pos": 83, "end_pos": 85, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YLX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLX2" }, { "id": "PS50835", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50835" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ig-like", "eco_id": "ECO_0000259", "start_pos": 15, "end_pos": 103, "start_aa": "Pro", "end_aa": "Gln", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0YLX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLX2" }, { "id": "PS50104", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50104" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "TIR", "eco_id": "ECO_0000259", "start_pos": 368, "end_pos": 520, "start_aa": "Lys", "end_aa": "Met", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 121, "end_pos": 123 }, { "start_pos": 138, "end_pos": 140 }, { "start_pos": 190, "end_pos": 192 }, { "start_pos": 463, "end_pos": 465 }, { "start_pos": 83, "end_pos": 85 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": 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"total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YLI1-1", "uniprot_ac": "A0A8V0YLI1", "uniprot_id": "A0A8V0YLI1_CHICK", "mass": { "chemical_mass": 29547.0, "monoisotopic_mass": 29547.0 }, "refseq": {}, "gene_names": [ { "name": "PAWR", "type": "recommended", "evidence": [ { "id": "A0A8V0YLI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLI1" } ] } ], "protein_names": [ { "name": "Pro-apoptotic WT1 regulator", "type": "synonym", "evidence": [ { "id": "A0A8V0YLI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLI1/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLI1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLI1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PAWR", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLI1", "locus": { "chromosome": "1", "start_pos": 39569524, "end_pos": 39642252, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013283", "url": "https://www.ensembl.org/id/ENSGALG00010013283" } ] } } ], "crossref": [ { "id": "A0A8V0YLI1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YLI1", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR026117", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026117", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YLI1", "url": "https://www.orthodb.org/?gene=A0A8V0YLI1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15093", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15093", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15093:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15093:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YLI1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLI1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLI1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLI1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "HHHLPAALPPERGAPPSGGAANCLGPGRAAPGKEPPPGPAAGREPAKQPPAAAAAVPGPTEGEEKPTGKGKSSGPSARKGKGQIEKRKLREKRRSTGVVNIPAAESLDEYEDDEAGQKERKKEDAITQQNTIQNESSSADSTGSYLIQDSSRMVSSRYKSTGNAPGDDALNRYSLTERTTYSRYSRDANSSGSSVPSNALEKRIEELERELAKERQENVRLMKMTQDKEEVIGKLKEEIDLLNRDLDDIEDENEQLKQENKTLLKVVGQLTR", "length": 272, "header": "tr|A0A8V0YLI1-1|A0A8V0YLI1_CHICK Isoform 1 of Pro-apoptotic WT1 regulator OS=Gallus gallus OX=9031 GN=PAWR PE=1 SV=1 CANONICAL=A0A8V0YLI1-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YLI1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLI1/entry#A0A8V0YLI1-1", "sequence": { "sequence": "HHHLPAALPPERGAPPSGGAANCLGPGRAAPGKEPPPGPAAGREPAKQPPAAAAAVPGPTEGEEKPTGKGKSSGPSARKGKGQIEKRKLREKRRSTGVVNIPAAESLDEYEDDEAGQKERKKEDAITQQNTIQNESSSADSTGSYLIQDSSRMVSSRYKSTGNAPGDDALNRYSLTERTTYSRYSRDANSSGSSVPSNALEKRIEELERELAKERQENVRLMKMTQDKEEVIGKLKEEIDLLNRDLDDIEDENEQLKQENKTLLKVVGQLTR", "length": 272, "header": "tr|A0A8V0YLI1-1|A0A8V0YLI1_CHICK Isoform 1 of Pro-apoptotic WT1 regulator OS=Gallus gallus OX=9031 GN=PAWR PE=1 SV=1 CANONICAL=A0A8V0YLI1-1" }, "locus": { "chromosome": "1", "start_pos": 39642250, "end_pos": 39574230, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031943.1", "url": "https://www.ensembl.org/id/ENSGALT00010031943.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018736.1", "url": "https://www.ensembl.org/id/ENSGALP00010018736.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": 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"https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLI1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLI1" } ], "pmid": "" }, { "name": "positive regulation of gene expression", "id": "GO:0010628", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010628", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLI1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLI1" } ], "pmid": "" }, { "name": "negative regulation of gene expression", "id": "GO:0010629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010629", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLI1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLI1" } ], "pmid": "" }, { "name": "apoptotic signaling pathway", "id": "GO:0097190", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097190", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLI1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLI1" } ], "pmid": "" }, { "name": "negative regulation of fibroblast proliferation", "id": "GO:0048147", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048147", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLI1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLI1" } ], "pmid": "" }, { "name": "positive regulation of neuron apoptotic process", "id": "GO:0043525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043525", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLI1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLI1" } ], "pmid": "" }, { "name": "positive regulation of cellular senescence", "id": "GO:2000774", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000774", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLI1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLI1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLI1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLI1" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLI1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLI1" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLI1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLI1" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLI1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLI1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "enzyme binding", "id": "GO:0019899", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019899", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLI1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLI1" } ], "pmid": "" }, { "name": "leucine zipper domain binding", "id": "GO:0043522", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043522", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLI1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLI1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 134, "end_pos": 136, "annotation": "n_glycosylation_sequon" }, { "start_pos": 189, "end_pos": 191, "annotation": "n_glycosylation_sequon" }, { "start_pos": 260, "end_pos": 262, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 60 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 134, "end_pos": 136 }, { "start_pos": 189, "end_pos": 191 }, { "start_pos": 260, "end_pos": 262 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YLI3-1", "uniprot_ac": "A0A8V0YLI3", "uniprot_id": "A0A8V0YLI3_CHICK", "mass": { "chemical_mass": 112558.0, "monoisotopic_mass": 112558.0 }, "refseq": { "ac": "XP_040502941", "name": "transcription elongation regulator 1 isoform X8", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040502941" }, "gene_names": [ { "name": "TCERG1", "type": "recommended", "evidence": [ { "id": "A0A8V0YLI3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLI3" } ] }, { "name": "TCERG1", "type": "synonym", "evidence": [ { "id": "XP_040502941", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040502941" } ] } ], "protein_names": [ { "name": "Transcription elongation regulator 1", "type": "recommended", "evidence": [ { "id": "A0A8V0YLI3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLI3/entry#names_and_taxonomy" } ] }, { "name": "TATA box-binding protein-associated factor 2S", "type": "synonym", "evidence": [ { "id": "A0A8V0YLI3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLI3/entry#names_and_taxonomy" } ] }, { "name": "Transcription factor CA150", "type": "synonym", "evidence": [ { "id": "A0A8V0YLI3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLI3/entry#names_and_taxonomy" } ] }, { "name": "transcription elongation regulator 1 isoform X8", "type": "synonym", "evidence": [ { "id": "XP_040502941", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040502941" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052544.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040502941", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040502941" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLI3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLI3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TCERG1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLI3", "locus": { "chromosome": "13", "start_pos": 17502889, "end_pos": 17470092, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013831", "url": "https://www.ensembl.org/id/ENSGALG00010013831" } ] } } ], "crossref": [ { "id": "A0A8V0YLI3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YLI3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000007528", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000007528", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00201", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00201", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "416349", "url": "https://www.ncbi.nlm.nih.gov/gene/416349", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001202", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001202", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002713", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002713", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036020", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036020", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036517", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036517", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045148", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045148", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057565", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057565", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5NTY1", "url": "https://www.orthodb.org/?gene=A0A1D5NTY1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YLI3", "url": "https://www.orthodb.org/?gene=A0A8V0YLI3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15377", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15377", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15377:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15377:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00397", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00397", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01846", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01846", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23517", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23517", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-9770562", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9770562", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_040502941", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040502941", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5NTY1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NTY1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5NTY1-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NTY1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLI3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLI3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLI3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLI3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAERGGGGGAGAGGGEGEAAAERFGGELRMAQQQALRFRGPAPPPNAVMRGPPPLMRPPPPFGMMRGPPPPPRPPFGRPPFDPNMPPMPPPGGIPPPMGPPHLQRPPFMPPPMGSMPPPPGMMFPPGMPPVTAPGTPAMPPAEEIWVENKTPDGKVYFYNARTRESAWTKPDGVKVIQQSELTPMLAAQAQVGASTPTTSSAAAAASPSTSSSTQSSTTSTTTTATSVSQTNSTPTTQDQTPSSGVSVATPSVSVSTSAPSATPVQTVPQPVPQTLPPAVPHAVPQPTAAIPAFPPVMVPPFRVPLPGMPIPLPGVLPGMAPPIVPMIHPQVAIAASPATLAGATAVSEWTEYKTADGKTYYYNNRTLESTWEKPQELKEKEKLEEKIKETIKEPTEEPLPMETEEEEPKEEPIKELIKEEPKEEEMTEEEKAAQKAKPVATTPIPGTPWCVVWTGDERVFFYNPTTRLSMWDRPDDLIGRADVDKIIQEPPHKKGMEEGKKLIREEHETTEEANEDEPIKIKKRKKDDNKDIDSEKEAAMEAEIKAARERAIVPLEARMKQFKDMLLERGVSAFSTWEKELHKIVFDPRYLLLNPKERKQVFDQYVKTRAEEERKEKKNKIMQAKEDFKKMMEESKINPRTTFSEFAAKHAKDSRFKAIEKMKDREALFNEFITAARKKEKEDSKTRGEKIKMDFFELLANHHLDSQSRWSKVKDKVETDPRYKAVDSSSQREDLFKQYIEKIAKNLDSEKEKELERQARIEASLREREREVQKARSEQTKEIDREREQHKREEAIQNFKALLSDMVRSSDVSWSDTRRTLRKDHRWESGSLLEREEKEKLFNEHIEALTKKKREHFRQLLDETSAITLTSTWKEVKKIIKEDPRCIKFSSSDRKKQREFEEYIRDKYITAKADFRTLLKETKFITYRSKKLIQESDQHLKDVEKILQNDKRYLVLDCVPEERRKLIVSYVDDLDRRGPPPPPTASEPTRRTTK", 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987, "header": "tr|A0A1D5NTY1-1|A0A1D5NTY1_CHICK Computationally mapped isoform of Transcription elongation regulator 1 OS=Gallus gallus OX=9031 GN=TCERG1 PE=1 SV=1 CANONICAL=A0A8V0YLI3-1" }, "locus": { "chromosome": "13", "start_pos": 17501874, "end_pos": 17471073, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033203.1", "url": "https://www.ensembl.org/id/ENSGALT00010033203.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019617.1", "url": "https://www.ensembl.org/id/ENSGALP00010019617.1" } ] } }, { "isoform_ac": "A0A8V0YLI3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLI3/entry#A0A8V0YLI3-1", "sequence": { "sequence": "MAERGGGGGAGAGGGEGEAAAERFGGELRMAQQQALRFRGPAPPPNAVMRGPPPLMRPPPPFGMMRGPPPPPRPPFGRPPFDPNMPPMPPPGGIPPPMGPPHLQRPPFMPPPMGSMPPPPGMMFPPGMPPVTAPGTPAMPPAEEIWVENKTPDGKVYFYNARTRESAWTKPDGVKVIQQSELTPMLAAQAQVGASTPTTSSAAAAASPSTSSSTQSSTTSTTTTATSVSQTNSTPTTQDQTPSSGVSVATPSVSVSTSAPSATPVQTVPQPVPQTLPPAVPHAVPQPTAAIPAFPPVMVPPFRVPLPGMPIPLPGVLPGMAPPIVPMIHPQVAIAASPATLAGATAVSEWTEYKTADGKTYYYNNRTLESTWEKPQELKEKEKLEEKIKETIKEPTEEPLPMETEEEEPKEEPIKELIKEEPKEEEMTEEEKAAQKAKPVATTPIPGTPWCVVWTGDERVFFYNPTTRLSMWDRPDDLIGRADVDKIIQEPPHKKGMEEGKKLIREEHETTEEANEDEPIKIKKRKKDDNKDIDSEKEAAMEAEIKAARERAIVPLEARMKQFKDMLLERGVSAFSTWEKELHKIVFDPRYLLLNPKERKQVFDQYVKTRAEEERKEKKNKIMQAKEDFKKMMEESKINPRTTFSEFAAKHAKDSRFKAIEKMKDREALFNEFITAARKKEKEDSKTRGEKIKMDFFELLANHHLDSQSRWSKVKDKVETDPRYKAVDSSSQREDLFKQYIEKIAKNLDSEKEKELERQARIEASLREREREVQKARSEQTKEIDREREQHKREEAIQNFKALLSDMVRSSDVSWSDTRRTLRKDHRWESGSLLEREEKEKLFNEHIEALTKKKREHFRQLLDETSAITLTSTWKEVKKIIKEDPRCIKFSSSDRKKQREFEEYIRDKYITAKADFRTLLKETKFITYRSKKLIQESDQHLKDVEKILQNDKRYLVLDCVPEERRKLIVSYVDDLDRRGPPPPPTASEPTRRTTK", "length": 995, "header": "tr|A0A8V0YLI3-1|A0A8V0YLI3_CHICK Isoform 1 of Transcription elongation regulator 1 OS=Gallus gallus OX=9031 GN=TCERG1 PE=1 SV=1 CANONICAL=A0A8V0YLI3-1" }, "locus": { "chromosome": "13", "start_pos": 17501874, "end_pos": 17470301, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033198.1", "url": "https://www.ensembl.org/id/ENSGALT00010033198.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019615.1", "url": "https://www.ensembl.org/id/ENSGALP00010019615.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 136, "start_aa": "Thr", "end_pos": 136, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr136", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 250, "start_aa": "Thr", "end_pos": 250, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr250", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 288, "start_aa": "Thr", "end_pos": 288, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr288", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 985, "start_aa": "Thr", "end_pos": 985, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr985", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "R-GGA-9770562", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9770562", "resource": "Reactome", "description": "mRNA Polyadenylation" } ], "orthologs": [], "go_annotation": { 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{ "uniprot_canonical_ac": "A0A8V0YLI9-1", "uniprot_ac": "A0A8V0YLI9", "uniprot_id": "A0A8V0YLI9_CHICK", "mass": { "chemical_mass": 11791.0, "monoisotopic_mass": 11791.0 }, "refseq": {}, "gene_names": [ { "name": "IFI27L2", "type": "recommended", "evidence": [ { "id": "A0A8V0YLI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLI9" } ] } ], "protein_names": [ { "name": "Interferon, alpha-inducible protein 27-like 2", "type": "synonym", "evidence": [ { "id": "A0A8V0YLI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLI9/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLI9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLI9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "IFI27L2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLI9", "locus": { "chromosome": "23", "start_pos": 4712757, "end_pos": 4702310, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013837", "url": "https://www.ensembl.org/id/ENSGALG00010013837" } ] } } ], "crossref": [ { "id": "A0A8V0YLI9", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YLI9", "database": "AlphaFoldDB", "categories": [] }, { "id": "403121", "url": "https://www.ncbi.nlm.nih.gov/gene/403121", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR009311", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009311", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038213", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038213", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:403121", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:403121", "database": "KEGG Pathway", 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"https://www.uniprot.org/uniprotkb/A0A8V0YLI9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLJ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLJ5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLJ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLJ5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YNR0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNR0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YNR0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNR0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YTS5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTS5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YTS5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTS5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTGGGRRPGDTEGTRRAMNPNIIKAAIGGGVATGVALVAAPLIVGAMGFTASGISAGSVAAKMMSAAAIANGGGVAAGSIVAVLQSIGAAGLSFGAKVGLASVCGLLGALIGLKIPSGMDGEAQKR", "length": 126, "header": "tr|A0A8V0YLI9-1|A0A8V0YLI9_CHICK Isoform 1 of Interferon, alpha-inducible protein 27-like 2 OS=Gallus gallus OX=9031 GN=IFI27L2 PE=3 SV=1 CANONICAL=A0A8V0YLI9-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YLI9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLI9/entry#A0A8V0YLI9-1", "sequence": { "sequence": "MTGGGRRPGDTEGTRRAMNPNIIKAAIGGGVATGVALVAAPLIVGAMGFTASGISAGSVAAKMMSAAAIANGGGVAAGSIVAVLQSIGAAGLSFGAKVGLASVCGLLGALIGLKIPSGMDGEAQKR", "length": 126, "header": "tr|A0A8V0YLI9-1|A0A8V0YLI9_CHICK Isoform 1 of Interferon, alpha-inducible protein 27-like 2 OS=Gallus gallus OX=9031 GN=IFI27L2 PE=3 SV=1 CANONICAL=A0A8V0YLI9-1" }, "locus": { "chromosome": "23", "start_pos": 4705768, "end_pos": 4704538, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033208.1", "url": "https://www.ensembl.org/id/ENSGALT00010033208.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019621.1", "url": "https://www.ensembl.org/id/ENSGALP00010019621.1" } ] } }, { "isoform_ac": "A0A8V0YLJ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLI9/entry#A0A8V0YLJ5-1", "sequence": { "sequence": "MNPNIIKAAIGGGVATGVALVAAPLIVGAMGFTASGISAGSVAAKMMSAAAIANGGGVAAGSIVAVLQSIDTVLQLSYDPHWTPILESLYD", "length": 91, "header": "tr|A0A8V0YLJ5-1|A0A8V0YLJ5_CHICK Computationally mapped isoform of Interferon, alpha-inducible protein 27-like 2 OS=Gallus gallus OX=9031 GN=IFI27L2 PE=3 SV=1 CANONICAL=A0A8V0YLI9-1" }, "locus": { "chromosome": "23", "start_pos": 4710528, "end_pos": 4705001, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033217.1", "url": "https://www.ensembl.org/id/ENSGALT00010033217.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019626.1", "url": "https://www.ensembl.org/id/ENSGALP00010019626.1" } ] } }, { "isoform_ac": "A0A8V0YNR0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLI9/entry#A0A8V0YNR0-1", "sequence": { "sequence": "MLQPAAMNPNIIKAAIGGGVATGVALVAAPLIVGAMGFTASGISAGSVAAKMMSAAAIANGGGVAAGSIVAVLQSIGAAGLSFGAKVGLASVCGLLGALIGLKIPSGMDGEAQKR", "length": 115, "header": "tr|A0A8V0YNR0-1|A0A8V0YNR0_CHICK Computationally mapped isoform of Interferon, alpha-inducible protein 27-like 2 OS=Gallus gallus OX=9031 GN=IFI27L2 PE=3 SV=1 CANONICAL=A0A8V0YLI9-1" }, "locus": { "chromosome": "23", "start_pos": 4705768, "end_pos": 4704909, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033206.1", "url": "https://www.ensembl.org/id/ENSGALT00010033206.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019620.1", "url": "https://www.ensembl.org/id/ENSGALP00010019620.1" } ] } }, { "isoform_ac": "A0A8V0YTS5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLI9/entry#A0A8V0YTS5-1", "sequence": { "sequence": "MNPNIIKAAIGGGVATGVALVAAPLIVGAMGFTASGISAGSVAAKMMSAAAIANGGGVAAGSIVAVLQSIGAAGLSFGAKVGLASVCGLLGALIGLKIPSGMDGEAQKR", "length": 109, "header": "tr|A0A8V0YTS5-1|A0A8V0YTS5_CHICK Computationally mapped isoform of Interferon, alpha-inducible protein 27-like 2 OS=Gallus gallus OX=9031 GN=IFI27L2 PE=3 SV=1 CANONICAL=A0A8V0YLI9-1" }, "locus": { "chromosome": "23", "start_pos": 4705768, "end_pos": 4705001, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033211.1", "url": "https://www.ensembl.org/id/ENSGALT00010033211.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019623.1", "url": "https://www.ensembl.org/id/ENSGALP00010019623.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:403121", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:403121", "resource": "KEGG Pathway" }, { "id": "R-GGA-9909505", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9909505", "resource": "Reactome", "description": "Modulation of host responses by IFN-stimulated genes" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "molecular adaptor activity", "id": "GO:0060090", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060090", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLI9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLI9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "mitochondrial membrane", "id": "GO:0031966", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031966", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLI9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLI9" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLI9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLI9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "intrinsic apoptotic signaling pathway", "id": "GO:0097193", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097193", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLI9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLI9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YLK4-1", "uniprot_ac": "A0A8V0YLK4", "uniprot_id": "A0A8V0YLK4_CHICK", "mass": { "chemical_mass": 73817.0, "monoisotopic_mass": 73817.0 }, "refseq": { "ac": "XP_015143316", "name": "exocyst complex component 3-like protein isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015143316" }, "gene_names": [ { "name": "EXOC3L", "type": "recommended", "evidence": [ { "id": "A0A8V0YLK4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLK4" } ] }, { "name": "EXOC3L", "type": "synonym", "evidence": [ { "id": "XP_015143316", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015143316" } ] } ], "protein_names": [ { "name": "Exocyst complex component Sec6", "type": "recommended", "evidence": [ { "id": "A0A8V0YLK4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLK4/entry#names_and_taxonomy" } ] }, { "name": "exocyst complex component 3-like protein isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015143316", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015143316" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052536.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015143316.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015143316", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015143316" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLK4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLK4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "EXOC3L", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLK4", "locus": {} } ], "crossref": [ { "id": "A0A8V0YLK4", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YLK4", "database": "AlphaFoldDB", "categories": [] }, { "id": "423478", "url": "https://www.ncbi.nlm.nih.gov/gene/423478", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR010326", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010326", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042532", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042532", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:423478", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423478", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CCLLRTV", "url": "https://omabrowser.org/oma/group/CCLLRTV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YLK4", "url": "https://www.orthodb.org/?gene=A0A8V0YLK4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21292", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21292", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21292:SF12", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21292:SF12", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF06046", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06046", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015143316", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015143316", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YLK4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLK4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLK4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLK4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKKIKCPYGASMGRGHKREKGAGENAKMLPKAKEREKQETKWVDKLKCSVSNLVETVSDRKKAAVKKDKSKNEAGNLLEMETNMKEEEGEMPAEEIIRGLIEQGKFSQACLYISRLEQSGNDGVGKSESLYTLLAERMLSAVSKALGGSDEMLLQTLQSVGEPLKWQKQKKEEWLSSEQGMEPSSTWRPNFWGKDLEKELTQYWTAQIPHFIPTGDTDETALKQHLSQLETTFLPKLEHRSGFFKEAGLLIPYARCCHASLSSHFSALTDSEHCTFSQGLLVYEWCLKAYRRGSGTWLGHRQSSEHIDVQSLMWIILKTEEKLLAVARKEVGKALNEAFDAGKTPCTDAAIIQILTEKTKAAHHISESLREKVEAVCLEEYLSFLDSYENKVKSLLQHDGFHGISSSLRTIENFCILRNVWYNLTYLCSASTDQDVKIKGIIDRTEDKITEHLLQTVTAEVKGTLKDHFRKSDSGFGRILEFLQQSFLVFKKKKTEKYQGLVKSVNNIITEEYVQALLATSRKSSVRRRRQIVSKMEEDHRMLQTTFKECLGPTADALKDPIKIILGLIQAPDAEGTKIALLPMLSQFPDLREEHLSAVLDIKESLRQEDRIALLKIFHDNCRKPDIESNLLFEDIEVEGGMCARCCCFCS", "length": 651, "header": "tr|A0A8V0YLK4-1|A0A8V0YLK4_CHICK Isoform 1 of Exocyst complex component Sec6 OS=Gallus gallus OX=9031 GN=EXOC3L PE=3 SV=1 CANONICAL=A0A8V0YLK4-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YLK4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLK4/entry#A0A8V0YLK4-1", "sequence": { "sequence": "MKKIKCPYGASMGRGHKREKGAGENAKMLPKAKEREKQETKWVDKLKCSVSNLVETVSDRKKAAVKKDKSKNEAGNLLEMETNMKEEEGEMPAEEIIRGLIEQGKFSQACLYISRLEQSGNDGVGKSESLYTLLAERMLSAVSKALGGSDEMLLQTLQSVGEPLKWQKQKKEEWLSSEQGMEPSSTWRPNFWGKDLEKELTQYWTAQIPHFIPTGDTDETALKQHLSQLETTFLPKLEHRSGFFKEAGLLIPYARCCHASLSSHFSALTDSEHCTFSQGLLVYEWCLKAYRRGSGTWLGHRQSSEHIDVQSLMWIILKTEEKLLAVARKEVGKALNEAFDAGKTPCTDAAIIQILTEKTKAAHHISESLREKVEAVCLEEYLSFLDSYENKVKSLLQHDGFHGISSSLRTIENFCILRNVWYNLTYLCSASTDQDVKIKGIIDRTEDKITEHLLQTVTAEVKGTLKDHFRKSDSGFGRILEFLQQSFLVFKKKKTEKYQGLVKSVNNIITEEYVQALLATSRKSSVRRRRQIVSKMEEDHRMLQTTFKECLGPTADALKDPIKIILGLIQAPDAEGTKIALLPMLSQFPDLREEHLSAVLDIKESLRQEDRIALLKIFHDNCRKPDIESNLLFEDIEVEGGMCARCCCFCS", "length": 651, "header": "tr|A0A8V0YLK4-1|A0A8V0YLK4_CHICK Isoform 1 of Exocyst complex component Sec6 OS=Gallus gallus OX=9031 GN=EXOC3L PE=3 SV=1 CANONICAL=A0A8V0YLK4-1" }, "locus": { "chromosome": "5", "start_pos": 49696346, "end_pos": 49680512, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010037812.1", 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], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "SNARE binding", "id": "GO:0000149", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000149", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLK4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLK4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "exocyst", "id": "GO:0000145", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000145", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLK4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLK4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 423, "end_pos": 425, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], 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"MSEDTVHNLPTALDSVSYEIQNRAGSENSLLDDDDDDDYFLNSGDLASIPVVGSDNEDDQNFTPKDTLPSEDHLEEGKRITEHELDSEKDIQIENAIQKDLTSPFEQGPVFKSIRKDFSITRDNGKETFSTKDKNREGNLQEHEKRLEKIPKDTDSRLKSSFLDKAVHNQVEETLRTQLAPQTPETNFRESSYLFSSKESIGQELGNSFAPNIRIKEEPLDDEYDKAMAPQQGLLDKIKDEPDNSEEYGQQPKTQEGELKISAVFSVSGSPLAPQLSSGFQPAVASSGMSKMLPSVPGTAVRVSCSGCKKILQKGQTAYQRKGSTQLFCSTLCLTGYTVPACRPPASTKKTCSSCSKEILNPKDVITAQFDNTNSSKDFCSQSCLSTYEMKRKPIITIHTNSISTKCSMCQKNAVIRHEVNYQNVVHKLCSDACFSKFRSANNLTMNCCENCGGYCYSGSGQCRMLQIEGQSKKFCSSTCVTLYKQKSAKITPCALCKSLRSSAEMIESTNNSGKTELFCSVNCLSAYRVKMVTSSGVQVQCNSCKTSANPQYHLAMSDGSVRNFCSYNCVVAFQNLFNKPAGVNSSVVPLSQGQVIVSIPSGTTVSAGGTTSTASPSSGSSSAAAGLQRLAAQSQQVTFARKVVKLWCQHCNRLFATKPELLDFKGKMFQFCGKTCCDEYKKRRSVTALCEYCRTEKIIKETVRIAGIDKPFCSEGCKLLYKHDLAKRWGNHCKMCSYCLQTSPKLVQNLFGGRMEEFCSEECMSKFTVLFYQMAKCDGCKRQGKLSESLKWQGEVKHFCNLLCILMFCKQQRIPDPPASNNTANPSTAPASSSGPPSLRKDSTPVIANVVSLASTPAAQPTVNSNNVLQGAVPTVTAKIIGDASTQTDALKLPSSQPPRLLKNKALLCKPITQTKATSCKPHTQNKECQTEEEEVQPKIIVVPVPVPVFVPVPLHLYTQYTPVPLGMPVPVPVPMLFPTTLDNADKILETIQDIKEKIPISPFEADLLQMAEMIAEDEEKDKTHSHGGSQTSEHELFLDPKMFEKDQGSTYSGDLESEAVSTPHSWEEELNHYALRSNALPEPDPEPKQISKGEVEQDLEADFPSDSFDPLSKGLGLHSRSRARRRHRDGFPQPKRRGRKKSVVAVEPRNLMQGSYPGCSVSGMTLKYMYGVNAWKNWVQWKNAQEEQGDLKFSVRPVKLKEDILSCTFAELSFGLCQFIQEVRRPNGEKYDPDSILYLCLGIQQYLFENGRIDNIFTEPYSRFMIELTKLLKIWEPTILPNGYMFSRIEEEHLWECKQLGAYSPIVLLNTLLFFNTKYFQLKNVSEHLKLSFAHVMRRTRTLKYNTKTTYLRFFPPFQKQEVESDKLSVGKRKRGEDEEISTAVEMAENADNPLRCPVRLYEFYLSKCSESVKQRSDVFYLQPERSCVPNSPMWYSTLPIDPGTLDIMLTRILMVREVHEELAKVKSEDSDIELSD", "length": 1479, "header": "tr|A0A8V0YLL5-1|A0A8V0YM13_CHICK Computationally mapped isoform of Zinc finger MYM-type containing 4 OS=Gallus gallus OX=9031 GN=ZMYM4 PE=4 SV=1 CANONICAL=A0A8V0YM13-1" }, "locus": { "chromosome": "23", "start_pos": 4734420, "end_pos": 4710004, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033281.1", "url": "https://www.ensembl.org/id/ENSGALT00010033281.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019647.1", "url": "https://www.ensembl.org/id/ENSGALP00010019647.1" } ] } }, { "isoform_ac": "A0A8V0YM13-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM13/entry#A0A8V0YM13-1", "sequence": { "sequence": "MASWCWIRRWGHSQGCEGSHDAKLGVRHGARRGLRWCETQHEAKLEFEDKSDAVFDITEKCSEILDAEMSEDTVHNLPTALDSVSYEIQNRAGSENSLLDDDDDDDYFLNSGDLASIPVVGSDNEDDQNFTPKDTLPSEDHLEEGKRITEHELDSEKDIQIENAIQKDLTSPFEQGPVFKSIRKDFSITRDNGKETFSTKDKNREGNLQEHEKRLEKIPKDTDSRLKSSFLDKAVHNQVEETLRTQLAPQTPETNFREYGQQPKTQEGELKISAVFSVSGSPLAPQLSSGFQPAVASSGMSKMLPSVPGTAVRVSCSGCKKILQKGQTAYQRKGSTQLFCSTLCLTGYTVPACRPPASTKKTCSSCSKEILNPKDVITAQFDNTNSSKDFCSQSCLSTYEMKRKPIITIHTNSISTKCSMCQKNAVIRHEVNYQNVVHKLCSDACFSKFRSANNLTMNCCENCGGYCYSGSGQCRMLQIEGQSKKFCSSTCVTLYKQKSAKITPCALCKSLRSSAEMIESTNNSGKTELFCSVNCLSAYRVKMVTSSGVQVQCNSCKTSANPQYHLAMSDGSVRNFCSYNCVVAFQNLFNKPAGVNSSVVPLSQGQVIVSIPSGTTVSAGGTTSTASPSSGSSSAAAGLQRLAAQSQQVTFARKVVKLWCQHCNRLFATKPELLDFKGKMFQFCGKTCCDEYKKRRSVTALCEYCRTEKIIKETVRIAGIDKPFCSEGCKLLYKHDLAKRWGNHCKMCSYCLQTSPKLVQNLFGGRMEEFCSEECMSKFTVLFYQMAKCDGCKRQGKLSESLKWQGEVKHFCNLLCILMFCKQQRIPDPPASNNTANPSTAPASSSGPPSLRKDSTPVIANVVSLASTPAAQPTVNSNNVLQGAVPTVTAKIIGDASTQTDALKLPSSQPPRLLKNKALLCKPITQTKATSCKPHTQNKECQTEEEEVQPKIIVVPVPVPVFVPVPLHLYTQYTPVPLGMPVPVPVPMLFPTTLDNADKILETIQDIKEKIPISPFEADLLQMAEMIAEDEEKDKTHSHGGSQTSEHELFLDPKMFEKDQGSTYSGDLESEAVSTPHSWEEELNHYALRSNALPEPDPEPKQISKGEVEQDLEADFPSDSFDPLSKGLGLHSRSRARRRHRDGFPQPKRRGRKKSVVAVEPRNLMQGSYPGCSVSGMTLKYMYGVNAWKNWVQWKNAQEEQGDLKFSVRPVKLKEDILSCTFAELSFGLCQFIQEVRRPNGEKYDPDSILYLCLGIQQYLFENGRIDNIFTEPYSRFMIELTKLLKIWEPTILPNGYMFSRIEEEHLWECKQLGAYSPIVLLNTLLFFNTKYFQLKNVSEHLKLSFAHVMRRTRTLKYNTKTTYLRFFPPFQKQEVESDKLSVGKRKRGEDEEISTAVEMAENADNPLRCPVRLYEFYLSKCSESVKQRSDVFYLQPERSCVPNSPMWYSTLPIDPGTLDIMLTRILMVREVHEELAKVKSEDSDIELSD", "length": 1490, "header": "tr|A0A8V0YM13-1|A0A8V0YM13_CHICK Isoform 1 of Zinc finger MYM-type containing 4 OS=Gallus gallus OX=9031 GN=ZMYM4 PE=4 SV=1 CANONICAL=A0A8V0YM13-1" }, "locus": { "chromosome": "23", "start_pos": 4743956, "end_pos": 4710004, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033286.1", "url": "https://www.ensembl.org/id/ENSGALT00010033286.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019650.1", "url": "https://www.ensembl.org/id/ENSGALP00010019650.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YM13", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM13" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 129, "end_pos": 131, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1337, "end_pos": 1339, "annotation": "n_glycosylation_sequon" }, { "start_pos": 385, "end_pos": 387, "annotation": "n_glycosylation_sequon" }, { "start_pos": 454, "end_pos": 456, "annotation": "n_glycosylation_sequon" }, { "start_pos": 522, "end_pos": 524, "annotation": "n_glycosylation_sequon" }, { "start_pos": 596, "end_pos": 598, "annotation": "n_glycosylation_sequon" }, { "start_pos": 833, "end_pos": 835, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YM13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM13" }, { "id": "SM00746", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00746" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "TRASH", "eco_id": "ECO_0000259", "start_pos": 316, "end_pos": 352, "start_aa": "Cys", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 129, "end_pos": 131 }, { "start_pos": 1337, "end_pos": 1339 }, { "start_pos": 385, "end_pos": 387 }, { "start_pos": 454, "end_pos": 456 }, { "start_pos": 522, "end_pos": 524 }, { "start_pos": 596, "end_pos": 598 }, { "start_pos": 833, "end_pos": 835 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YLM1-1", "uniprot_ac": "A0A8V0YLM1", "uniprot_id": "A0A8V0YLM1_CHICK", "mass": { "chemical_mass": 40562.0, "monoisotopic_mass": 40562.0 }, "refseq": {}, "gene_names": [ { "name": "PARVB", "type": "recommended", "evidence": [ { "id": "A0A8V0YLM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLM1" } ] } ], "protein_names": [ { "name": "Parvin beta", "type": "synonym", "evidence": [ { "id": "A0A8V0YLM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLM1/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLM1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLM1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PARVB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLM1", "locus": { "chromosome": "1", "start_pos": 69257381, "end_pos": 69198524, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013301", "url": "https://www.ensembl.org/id/ENSGALG00010013301" } ] } } ], "crossref": [ { "id": "A0A8V0YLM1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YLM1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000014201", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000014201", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd21336", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd21336", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd21338", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd21338", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "418235", "url": "https://www.ncbi.nlm.nih.gov/gene/418235", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001715", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001715", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028433", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028433", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036872", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036872", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:418235", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418235", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A1L1RKB6", "url": "https://www.orthodb.org/?gene=A0A1L1RKB6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q2TSL7", "url": "https://www.orthodb.org/?gene=A0A3Q2TSL7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YLM1", "url": "https://www.orthodb.org/?gene=A0A8V0YLM1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12114", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12114", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12114:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12114:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00307", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00307", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-446388", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-446388", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A1L1RKB6", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RKB6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1L1RKB6-1", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RKB6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2TSL7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TSL7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2TSL7-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TSL7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLM1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLM1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLM1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLM1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSSAPIRSPTLRPHRMKKDESFLGKLGGTLARKKKAKEVSDLQEEGKNAINAPMNPSAVDIHPEDTLLEENEERTMIDPNSKEDPKFKELIKVLIDWINDVLVEERIIVKQLEEDLYDGQVLQKLLEKLADRKLNVAEVTQSEIGQKQKLQTVLEAVHDLLRPHGWTIKWNVDSIHGKNLISILHLLVALAMHFRAPIRLPEHVSVQVVVVRKREGLLQTTHVTEELTTTTEMMMGRFERDAFDTLFDHAPDKLSVVKKSLITFVNKHLNKLNLEVTELETQFADGVYLVLLMGLLEDYFVPLHNFYLTPESFDQKVHNVSFAFELMQDGGLKKPKARPEGMDVTRVFELHMKT", "length": 354, "header": "tr|A0A8V0YLM1-1|A0A8V0YLM1_CHICK Isoform 1 of Parvin beta OS=Gallus gallus OX=9031 GN=PARVB PE=1 SV=1 CANONICAL=A0A8V0YLM1-1" }, "isoforms": [ { "isoform_ac": "A0A1L1RKB6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLM1/entry#A0A1L1RKB6-1", "sequence": { "sequence": "MGRWIAVSDLQEEGKNAINAPMNPSAVDIHPEDTLLEENEERTMIDPNSKEDPKFKELIKVLIDWINDVLVEERIIVKQLEEDLYDGQVLQKLLEKLADRKLNVAEVTQSEIGQKQKLQTVLEAVHDLLRPHGWTIKWNVDSIHGKNLISILHLLVALAMHFRAPIRLPEHVSVQVVVVRKREGLLQTTHVTEELTTTTEMMMGRFERDAFDTLFDHAPDKLSVVKKSLITFVNKHLNKLNLEVTELETQFADGVYLVLLMGLLEDYFVPLHNFYLTPESFDQKVHNVSFAFELMQDGGLKKPKARPEDVVNLDLKSTLRVLYNLFTKYKNVE", "length": 333, "header": "tr|A0A1L1RKB6-1|A0A1L1RKB6_CHICK Computationally mapped isoform of Parvin beta OS=Gallus gallus OX=9031 GN=PARVB PE=1 SV=2 CANONICAL=A0A8V0YLM1-1" }, "locus": { "chromosome": "1", "start_pos": 69254436, "end_pos": 69216825, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031995.1", "url": "https://www.ensembl.org/id/ENSGALT00010031995.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018785.1", "url": "https://www.ensembl.org/id/ENSGALP00010018785.1" } ] } }, { "isoform_ac": "A0A3Q2TSL7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLM1/entry#A0A3Q2TSL7-1", "sequence": { "sequence": "MAGLLCKRRKKGVSDLQEEGKNAINAPMNPSAVDIHPEDTLLEENEERTMIDPNSKEDPKFKELIKVLIDWINDVLVEERIIVKQLEEDLYDGQVLQKLLEKLADRKLNVAEVTQSEIGQKQKLQTVLEAVHDLLRPHGWTIKWNVDSIHGKNLISILHLLVALAMHFRAPIRLPEHVSVQVVVVRKREGLLQTTHVTEELTTTTEMMMGRFERDAFDTLFDHAPDKLSVVKKSLITFVNKHLNKLNLEVTELETQFADGVYLVLLMGLLEDYFVPLHNFYLTPESFDQKVHNVSFAFELMQDGGLKKPKARPEDVVNLDLKSTLRVLYNLFTKYKNVE", "length": 339, "header": "tr|A0A3Q2TSL7-1|A0A3Q2TSL7_CHICK Computationally mapped isoform of Parvin beta OS=Gallus gallus OX=9031 GN=PARVB PE=1 SV=1 CANONICAL=A0A8V0YLM1-1" }, "locus": { "chromosome": "1", "start_pos": 69254436, "end_pos": 69217400, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031994.1", "url": "https://www.ensembl.org/id/ENSGALT00010031994.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018784.1", "url": "https://www.ensembl.org/id/ENSGALP00010018784.1" } ] } }, { "isoform_ac": "A0A8V0YLM1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLM1/entry#A0A8V0YLM1-1", "sequence": { "sequence": "MSSAPIRSPTLRPHRMKKDESFLGKLGGTLARKKKAKEVSDLQEEGKNAINAPMNPSAVDIHPEDTLLEENEERTMIDPNSKEDPKFKELIKVLIDWINDVLVEERIIVKQLEEDLYDGQVLQKLLEKLADRKLNVAEVTQSEIGQKQKLQTVLEAVHDLLRPHGWTIKWNVDSIHGKNLISILHLLVALAMHFRAPIRLPEHVSVQVVVVRKREGLLQTTHVTEELTTTTEMMMGRFERDAFDTLFDHAPDKLSVVKKSLITFVNKHLNKLNLEVTELETQFADGVYLVLLMGLLEDYFVPLHNFYLTPESFDQKVHNVSFAFELMQDGGLKKPKARPEGMDVTRVFELHMKT", "length": 354, "header": "tr|A0A8V0YLM1-1|A0A8V0YLM1_CHICK Isoform 1 of Parvin beta OS=Gallus gallus OX=9031 GN=PARVB PE=1 SV=1 CANONICAL=A0A8V0YLM1-1" }, "locus": { "chromosome": "1", "start_pos": 69250045, "end_pos": 69198706, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031997.1", "url": "https://www.ensembl.org/id/ENSGALT00010031997.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018787.1", "url": "https://www.ensembl.org/id/ENSGALP00010018787.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:418235", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418235", "resource": "KEGG Pathway" }, { "id": "R-GGA-446388", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-446388", "resource": "Reactome", "description": "Regulation of cytoskeletal remodeling and cell spreading by IPP complex components" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "actin binding", "id": "GO:0003779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003779", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLM1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLM1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 7, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLM1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLM1" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLM1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLM1" } ], "pmid": "" }, { "name": "focal adhesion", "id": "GO:0005925", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005925", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLM1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLM1" } ], "pmid": "" }, { "name": "actin cytoskeleton", "id": "GO:0015629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015629", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLM1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLM1" } ], "pmid": "" }, { "name": "lamellipodium", "id": "GO:0030027", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030027", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLM1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLM1" } ], "pmid": "" }, { "name": "Z disc", "id": "GO:0030018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030018", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLM1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLM1" } ], "pmid": "" }, { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLM1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLM1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "actin cytoskeleton organization", "id": "GO:0030036", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030036", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLM1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLM1" } ], "pmid": "" }, { "name": "lamellipodium 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], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 319, "end_pos": 321, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YLM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLM1" }, { "id": "PS50021", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50021" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Calponin-homology (CH)", "eco_id": "ECO_0000259", "start_pos": 88, "end_pos": 195, "start_aa": "Lys", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], 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"database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLM3/entry#names_and_taxonomy" } ] }, { "name": "5'-3' exoribonuclease 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_040535308", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040535308" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052581.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040535308", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040535308" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLM3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLM3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "XRN1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLM3", "locus": { "chromosome": "9", "start_pos": 10090871, "end_pos": 10123442, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010015719", "url": "https://www.ensembl.org/id/ENSGALG00010015719" } ] } } ], "crossref": [ { "id": "cd18673", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18673", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "424778", "url": "https://www.ncbi.nlm.nih.gov/gene/424778", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004859", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004859", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016494", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016494", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027073", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027073", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040992", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040992", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041106", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041106", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041385", "url": 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Classification" ] }, { "id": "PTHR12341:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12341:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03159", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03159", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17846", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17846", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF18129", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18129", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF18332", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18332", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF18334", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18334", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-450385", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-450385", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_040535308", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040535308", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YLM3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLM3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLM3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLM3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGVPKFYRWISERYPCLSQVLKEHQIPEFDNLYLDMNGIIHQCSHPNDDDVHFRISEDKIFADIFHYLEVLFRIIKPRKVFFMAVDGVAPRAKMNQQRGRRFRSAKEAEDKIKKALEKGEILPTEARFDSNCITPGTEFMARLHEHLKYFVNMKISTDKSWQGITVYLSGHETPGEGEHKIMEFIRSEKAKPHHDPNTRHCLYGLDADLIMLGLTTHEAHFALLREEVRFGGKKSQRACAPEETTFHLLHLSLMREYIDYEFSPVKDKISFDYDIEKIIDDWILMGFLVGNDFIPHLPHLHINHDALPLLYRTYMAILPELGGYINENGHLNLKRFEKYLTRLSDFDREHFSEVFVDLKWFESKVGNKYLNEAAGIAAEEARNNKQKKRKAQENSLCLAALEKNEDEVVTSKTVLEDEPEDDDLFETEFRQYKRTYYMTKMGIEVVSDDFLADQAECYVQAIQWILHYYYHGVQSWSWYYPYHYAPYLSDIRNISELKIQFELGKPFMPFEQLLAVLPAASKDLLPRCYQHLMVSQDSPIIEYYPLDFKTDLNGKQQEWEAVVLIPFIDEKRLLEAMESCNKCLKEEEKRRNVHSACLMYWYDKDAEFPYTSPWPEKFPAIERCHTRYKTIPLDAWHVEITHNKITKINKSALYFCGFPTLKHIKHKFYLKKSGVQVFQQSSHGENMMLEILTDENSKEQTVENVASSVLGKVVFVNWPHLEEARVVAVSDGETKFYLEEPHGTQKLYMGNAVPPTKVTFVGDKEQSMWLKEVQGVSEHYQRRKGIIIHETSVVVYAQLLTGNRYQLNQNGQVYLEKQWSKQALPFVYQTVVKDIKAFDSRFSNIRTLDDLFPPGSTAFMLGSPYYGCMGEVQDSRDVIPEGRIRVVFSIPCEPQLDRLIQNQHKYSVKYNPAYILASRLGVSGYLVSRFTGSIFIGRGSKKNPHGDHKANVGLNLKFNKKNEEVPGYTKKVGNEWMYSSAVEQLLAEYLERVPELFSYIAKNSQEDIFYEDDIWPGEDENGAEKVQEIVAWLKAHPVSALSRSSCDLQILDAAIVEKIEEEIEKCKQRKSNKKVRVTVKPHLLYRPLEQQNGVVPDRDAEYRLFDRVVNVRENFSVPVGLRGTIIGIKGASRETDVLFEVLFDEEFLGGLTIRCSPARGYRLPSSALINLSHGVRSEMGNQKLTAIVKPQPAVNNYNSYASDLSSVCSQKVHLGGLNHSPRSLFVPTQQLNGRQHYNLRAENQGTSNSPHKGSFLSSNQKNKAQNKQDDEFCSIWQSLQGSGKSHHVQQNIHEKGAVLPQEIKLGSGNQFYKPGFNDGSFRSQQRKQEPYKKFKEDSRFTRGESQPHNKIPNKQNFAGVNKHNVKLLKRNESVPVIQKAASDSPCTSGKKDSELESLLASLKISKENEVQTSSKEARATNEEHLSPQSFAMKGTQMLKEILKIDGSDLETRNEAKSHVNDVPASPGRQDCHGAALQYRQTKKMAAYMNNPHSTGGPQSTPALGTGGHPFVGPQPTLSTPVSELSRICSLVGMSQPDFSFIKTPQTMTVCHIKLSNGLLVHGPQCHSEAEAKEKAALSALQRLSSVGVNLPFPPPVFPNYQPLGVPVPPGSLPPVFSQPPANIMPPSSHMFGPVSWGTPVPIHGKHYYPGSYPGNVSLAGTIPVGSHNQFIPLQVTKKRAASKKNFEFKEFQSSPQAAPLKNEQPVSSDHIQQDSSSAPLKSPQAAQSTVSFQDNAATPSVPRNKSAPNTSSKRKPRKLAVNFGTPKSAE", "length": 1770, "header": "tr|A0A8V0YLM3-1|A0A8V0YLM3_CHICK Isoform 1 of 5'-3' exoribonuclease 1 OS=Gallus gallus OX=9031 GN=XRN1 PE=1 SV=1 CANONICAL=A0A8V0YLM3-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YLM3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLM3/entry#A0A8V0YLM3-1", "sequence": { "sequence": "MGVPKFYRWISERYPCLSQVLKEHQIPEFDNLYLDMNGIIHQCSHPNDDDVHFRISEDKIFADIFHYLEVLFRIIKPRKVFFMAVDGVAPRAKMNQQRGRRFRSAKEAEDKIKKALEKGEILPTEARFDSNCITPGTEFMARLHEHLKYFVNMKISTDKSWQGITVYLSGHETPGEGEHKIMEFIRSEKAKPHHDPNTRHCLYGLDADLIMLGLTTHEAHFALLREEVRFGGKKSQRACAPEETTFHLLHLSLMREYIDYEFSPVKDKISFDYDIEKIIDDWILMGFLVGNDFIPHLPHLHINHDALPLLYRTYMAILPELGGYINENGHLNLKRFEKYLTRLSDFDREHFSEVFVDLKWFESKVGNKYLNEAAGIAAEEARNNKQKKRKAQENSLCLAALEKNEDEVVTSKTVLEDEPEDDDLFETEFRQYKRTYYMTKMGIEVVSDDFLADQAECYVQAIQWILHYYYHGVQSWSWYYPYHYAPYLSDIRNISELKIQFELGKPFMPFEQLLAVLPAASKDLLPRCYQHLMVSQDSPIIEYYPLDFKTDLNGKQQEWEAVVLIPFIDEKRLLEAMESCNKCLKEEEKRRNVHSACLMYWYDKDAEFPYTSPWPEKFPAIERCHTRYKTIPLDAWHVEITHNKITKINKSALYFCGFPTLKHIKHKFYLKKSGVQVFQQSSHGENMMLEILTDENSKEQTVENVASSVLGKVVFVNWPHLEEARVVAVSDGETKFYLEEPHGTQKLYMGNAVPPTKVTFVGDKEQSMWLKEVQGVSEHYQRRKGIIIHETSVVVYAQLLTGNRYQLNQNGQVYLEKQWSKQALPFVYQTVVKDIKAFDSRFSNIRTLDDLFPPGSTAFMLGSPYYGCMGEVQDSRDVIPEGRIRVVFSIPCEPQLDRLIQNQHKYSVKYNPAYILASRLGVSGYLVSRFTGSIFIGRGSKKNPHGDHKANVGLNLKFNKKNEEVPGYTKKVGNEWMYSSAVEQLLAEYLERVPELFSYIAKNSQEDIFYEDDIWPGEDENGAEKVQEIVAWLKAHPVSALSRSSCDLQILDAAIVEKIEEEIEKCKQRKSNKKVRVTVKPHLLYRPLEQQNGVVPDRDAEYRLFDRVVNVRENFSVPVGLRGTIIGIKGASRETDVLFEVLFDEEFLGGLTIRCSPARGYRLPSSALINLSHGVRSEMGNQKLTAIVKPQPAVNNYNSYASDLSSVCSQKVHLGGLNHSPRSLFVPTQQLNGRQHYNLRAENQGTSNSPHKGSFLSSNQKNKAQNKQDDEFCSIWQSLQGSGKSHHVQQNIHEKGAVLPQEIKLGSGNQFYKPGFNDGSFRSQQRKQEPYKKFKEDSRFTRGESQPHNKIPNKQNFAGVNKHNVKLLKRNESVPVIQKAASDSPCTSGKKDSELESLLASLKISKENEVQTSSKEARATNEEHLSPQSFAMKGTQMLKEILKIDGSDLETRNEAKSHVNDVPASPGRQDCHGAALQYRQTKKMAAYMNNPHSTGGPQSTPALGTGGHPFVGPQPTLSTPVSELSRICSLVGMSQPDFSFIKTPQTMTVCHIKLSNGLLVHGPQCHSEAEAKEKAALSALQRLSSVGVNLPFPPPVFPNYQPLGVPVPPGSLPPVFSQPPANIMPPSSHMFGPVSWGTPVPIHGKHYYPGSYPGNVSLAGTIPVGSHNQFIPLQVTKKRAASKKNFEFKEFQSSPQAAPLKNEQPVSSDHIQQDSSSAPLKSPQAAQSTVSFQDNAATPSVPRNKSAPNTSSKRKPRKLAVNFGTPKSAE", "length": 1770, "header": "tr|A0A8V0YLM3-1|A0A8V0YLM3_CHICK Isoform 1 of 5'-3' exoribonuclease 1 OS=Gallus gallus OX=9031 GN=XRN1 PE=1 SV=1 CANONICAL=A0A8V0YLM3-1" }, "locus": { "chromosome": "9", "start_pos": 10123410, "end_pos": 10091291, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010037843.1", "url": "https://www.ensembl.org/id/ENSGALT00010037843.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021849.1", "url": "https://www.ensembl.org/id/ENSGALP00010021849.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1500, "start_aa": "Thr", "end_pos": 1500, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1500", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "R-GGA-450385", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-450385", "resource": "Reactome", "description": "Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA" } ], "orthologs": [ { "uniprot_canonical_ac": "D4ABN8-1", "protein_name": "5'-3' exoribonuclease 1", "gene_name": "Xrn1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGVPKFYRWISERYPCLSEVVKEHQIPEFDNLYLDMNGIIHQCSHPNDDDVHFRISDDKIFTDIFHYLEVLFRIIKPRKVFFMAVDGVAPRAKMNQQRGRRFRSAKEAEDKIKKAIEKGETLPTEARFDSNCITPGTEFMARLHEHLKYFVNMKISTDKSWQGVTIYFSGHETPGEGEHKIMEFIRSEKAKPDHDPNTRHCLYGLDADLIMLGLTSHEAHFSLLREEVRFGGKKTQRVCAPEETTFHLLHLSLMREYIDYEFSALKEKITFKYDIEKIIDDWILMGFLVGNDFIPHLPHLHINHDALPLLYGTYIAILPELGGYINESGHLNLPRFERYLVKLSDFDREHFSEVFVDLKWFESKVGNKYLNEAAGAAAEEAKSCKDKRKVKGQENSLSWAALDKREGEGVASRDNFEDETEDDDLFETEFRQYKRTYYMTKMGVDVVSDEFLADQAACYVQAIQWILHYYYHGVQSWSWYYPYHYAPFLSDIRNISTLKIHFELGKPFKPFEQLLAVLPSASKTLLPTCYQHLMTSEDSPIIEYYPPDFKTDLNGKQQEWEAVVLIPFIDEKRLLEAMETCNHSLKKEERKRNQHSECLMCWYDSDTEFTYSSPWPEKFPAIERCSTRYKIISLDAWRVDINKNKITRVDQKALYFCGFPTLKHIKHKFFLKKSGVQVFQQSSRGENMMLEITVNAEPDELSIENIASSVLGKSVFVNWPHLEEARVVAVSDGETKFYMEEPPGTQKVYLGKTAPPCKVIQLSDKEQSNWTKEIQGISEQYLRRKGIMINETSAVVYAQLLTGRRYQVNQNGEVRLEKQWSKQSLPFVYQTIVKDVRAFDSRFSNIKTLDDLFPPRSVVFMLGTPYYGCTGEVQDSGDVITEGRIRVVFSIPCEPNLDALIQNQHKYSIKYNPGYVLAGRLGVSGYLVSRFTGSIFIGRGSRRNPHGDHKANVGLNLKFNKKNEEVPGYTKRVGSEWMYSSAAEQLLAEYIERAPELFSYIAQNSQEDVFYEDDIWPGESESGAEKVQEIITWLKGHPVSTLSRSSCDLHILDAAIVEKIEEEVEKCKQRKNNKKVRVTVKPHLLFRPLEQQHGAIPDRDAEFRLFDRVVNVRENFSVPVGLRGTIIGIKGANREADVLFEVLFDEEFPGGLTIRCSPGRGYRLPTSALVNLSHGSRCETGNQKLTAIVKPQPAVSHCSVNSSVSSGHMGGLNHSPQSLFLPTQVPTKGDDEFCNIWQSLQGSGKIQHLQPTVQEKGAVLPQEISQVTESHKSGFNDHSVRHQQRKHDPHRKFKEEYKSPKAECQNQKLSNKQTSGASARCNIKLLKRNESPGTSEAQKVVTSYPNAVHKPHSGIESFLASLNISKESEVQLPHGEPPDEAHLSPQSFAMKGTRMLKEILKIDSPDTTDSKNDVKKFDNEVMVSSSRRDEHGPSSHPKPTSHVSQPHSTNEYQSVDSVCWPGHMPPVSTPVTELSRICSLVGMPQPDFSFLRTTQTMTVCQVKLSNGLLVHGPQCHSESEAKERAALFALQQLGSLGVNFPLPPPIFTNYPPAVPPGAVPPVFPQPTANMMPSSSHLFGSVPWRPPVPVPGNAYHYPSYPATMPLAGGMPGGVHNQFIPLQVTKKRVANKKNFENKEAQSSQATPLQTNKPGSSEATRMTPQEGSPASSASSQATQPVSSHVETASQGHVVSHQRSAPSSSRRKSRKLAVNFSVSKPSE", "length": 1719 }, "evidence": [ { "id": "A0A8V0YLM3", "url": "https://omabrowser.org/oma/group/A0A8V0YLM3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E1BMZ8-1", "protein_name": "5'-3' exoribonuclease 1", "gene_name": "XRN1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGVPKFYRWISERYPCLSEVVKEHQIPEFDNLYLDMNGIIHQCSHPNDDDVHFRISDDKIFTDIFHYLEVLFRIIKPRKVFFMAVDGVAPRAKMNQQRGRRFRSAKEAEEKIKKAIEKGETLPAEARFDSNCITPGTEFMARLHEHLKYFVNMKISTDKSWQGVTIYFSGHETPGEGEHKIMEFIRSEKAKPDHDPNTRHCLYGLDADLIMLGLTSHEAHFSLLREEVRFGGKKTQRVCAPEETTFHLLHLSLMREYIDYEFSALKDKITFKYDIERIIDDWILMGFLVGNDFIPHLPHLHINHDALPLLYGTYITILPELGGYINESGHLNLPRFEKYLVKLSDFDREHFSEVFVDLKWFESKVGNKYLNEAAGVAAEEAKSYKEKKKSKGQENSICWAALDKNGEEVVTSKDNVEEEMEDDDLFETEFRQYKRTYYMTKMGVDVVSDDFLADQAACYVQAIQWILHYYYHGVQSWSWFYPYHYAPFLSDIRNISTLKIHFELGKPFKPFEQLLAVLPAASKNLLPACYQHLMTSDDSPIIEYYPPDFKTDLNGKQQEWEAVVLIPFIDEKRLLEAMETCNHSLKKEERKRNQHSECLMCWFDSNTEFTYPSPWPEKFPPVERCCARYKIISLDAWRIDISKNNITKVDQKALYFCGFPTLKHIKHKFFLKKSGVQVFQQSSRGENMMLEILVNAESDELSVENIASSVLGKSVFVNWPHLEEARVVGVSDGETKFYLEEPPGTQKLYLGRTAPPSKVVHLGDKEQCNWTKEVQGISEYYLRRKGIIINETSAVVYGQLLTGRKYQINQNGEVRLEKQWSKQVLPFVYQTIVKDIRAFDSRFSSIKTLDDLFPPRSMVFMLGTPYYGCTGEVQDSGDVITEGRIRVVFSIPCEPNLDALIQNQHKYSIKYNPGYVLASRLGVSGYLVSRFTGSIFIGRGSRRNPHGDHKANVGLNLKFNKKNEEVPGYTKKVGNEWMYSSAAEQLLAEYLERAPELFSYIAKNSQEDVFYEDDIWPGENENGAEKVQEIITWLKGHPVSTLSRSSCDLQILDAAIVEKIEEEIEKCKQRKNNKKVRVTVKPHLLYRPLEQQHGVIPDRDAEFRLFDRVVNVRENFSVPVGLRGTIIGIKGANREADVLFEVLFDEEFPGGLTIRCSPGRGYRLPTSALVNLSHGSRSETGNQKLTAIVKPQPAVNHYSSNSSVSSGHLGGLNHSPQSLFVPTQVPARDDDEFCNIWQSLQGSGKVQHFQPLLQEKGAVLPQEISQVTQHHKTGFNDNSVKPRKHEPHRKFKEECKSPKTESRSQKMSNRQPNPGIENFLASLNISKESEIQSSHHEEPPSEEHLSPQSFAMKGTRMLKEILKIDSSDSMDHKNEMKQFGNEVTVSSSRRDEYGSSSQPKQNKKLTSYMNKPHSASEYHNVQSMDSVCWPTGQIPPMSTPVTELSRICSLVGMPQPDFSFLRTPQTMTVCQVKLSNGLLVHGPQCHSENEAKEKAAFFAIQQLGSLGVNFPLPPPVFPSYPPAVPPGTIPPVFPQPTGWDHYGSNLALGAANIMPSSSHLFGSVPWGPPMPVPGKPFHHTSYAGTMPMAGGMPAGVHNQFIPLQVTKKRVANKKNFENKEAQSYQVTPLHTSQSASSDVTKGIPQETSSASLPSSQIPQPASSFQVAAASPGHSMPHQKSAPSSSRRKSRKLAVNFGVSKPSE", "length": 1703 }, "evidence": [ { "id": "A0A8V0YLM3", "url": "https://omabrowser.org/oma/group/A0A8V0YLM3/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "E1JJR3-1", "protein_name": "5'-3' exoribonuclease 1", "gene_name": "pcm", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MGVPKFFRYISERYPCLSELAREHCIPEFDNLYLDMNGIVHNCSHPDDNNIHFHLEEEQIFQEIFNYVDKLFYLIKPQRLFFLSVDGVAPRAKMNQQRSRRFRTAREAEQQEAKAAQRGELREHERFDSNCITPGTEFMVRLQEGLRAFLKTKISTDPLWQRCTVILSGQEAPGEGEHKIMDYIRYMKTQPDYDPNTRHCLYGLDADLIILGLCTHELHFVVLREEVKFGRNVKRTSVEETRFFLLHLGLLREYLELEFDALRTDEHKLDIAQLIDDWVLMGFLVGNDFIPHLPCLHISSNALPLLYRTYIGIYPTLGGNINENGKLNLRRLQIFISALTEVELDHFKEHADDLKYMNNKSEAFDMDVGEITESQNLDSDLGALINKSMLLYDDDSEEDCSDENAVLLKEFQNYKRNFYRNKFKRDPNDELIEELCHHYVNALQWVLDYYYRGVQSWDWYYPFHYTPFISDLKNIEQVEIAFHMGTPFLPFQQLLAVLPAASAKLLPVAYHDLMLLPTSPLAEFYPLEFESDLNGKKHDWEAVVLIPFIDEGRLLAAMLPCEAQLSLEERERNRHGPMYVYKYSTVAQGPMPAYPPLRALPVLYCTEVAKWSHEIAVNLPYSVCIELPNAARTVFFPGFPTMQHLPFDFELRNDRVKVFEQVSRNQNIVLKPRKRQLEDTLTAVASQYLGKVIHVGWPHLVKAIVVRVATRDQRVDSEGITLNDSRRFDSECKALQEHFINRMGIQFANYDVLVYVRTFAGNSTEFRDKGALMVRDSWSSSVTGYPAQGVVADLTVWERMRKNFLNVEHYFPVGSTIFLITDPYYGSEGTVQDPRLAYTNGRIQVSIMVRPEPKVNAARQLQEERDRDYLSTFQVCNLLRISGRTLGRLSGTVWVVLGPRRQKMENVTKHNIGLQLKYPRQNEERAGYCFRTNNQWYYSSLAVDLMRNYCQRYPDVIDFFGDSNDRAEFVFEQDVFPNAVGHRRVEELANWVRQQPHMKVERISCGSKTVCRETIELLIAAVDDLRSLPVKHVKLQVKPHLLIKPNVTLPDVYRSKRPVRLFDRVVIVRTIYMVPVGTKGTVIGIHPVTDPNPVRLECVHAVDTFCKVLFDSPVPNCNNIHGIAEDRVYKVPEIALVIIKTDEEGKKQNDCELPVRDPQPNQAQDEPVRATSSRYVTAAGSTSVPITMKTQISDEFVKTRSDPIARTDSYKPSSEPKPVPVPEQITNWRERVSTPTNKPQPAPNNWRINRSSSRQQGGSIFVAPPTKTPDAAASTASTAFTAASSATLTPLDQTLALMSVLGVGEDQSSPPLQEAVQQQRPPLLQQQRAPFPGQMPNLPKPPLFWQQEAQKQEALQQEAQQQEAQKKQQQAHAQMEPERINSQHFYRSGQTGAALNQPPLGAPSKRQWHEWVHPRMQHANAFHAGVNNGYQMRPKKNIAAQSTFNNNVHMHLQQPYYPNQQQQQQQQQPLQLTEINNAPPRYSTIQDFVPIQAYRPKKLNRVQPAGRQDVDATKNPSRSPVLQQPTNETIDTKASSSLPVQSAGEQVIGLMQTLEIKQPAASQSESDGVSTGSANAPTATTSSQAVNRRKHRVPRIGAKFDLEYILPDSPHPT", "length": 1613 }, "evidence": [ { "id": "A0A8V0YLM3", "url": "https://omabrowser.org/oma/group/A0A8V0YLM3/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "F1Q4U5-1", "protein_name": "5'-3' exoribonuclease 1", "gene_name": "xrn1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MGVPKFYRWISERYPCLSEVVKEHQIPEFDNLYLDMNGIIHQCSHPNDEDVHFRISEEKIFADIFHYLEVLFRIIKPRKVFFMAVDGVAPRAKMNQQRGRRFRSAKEAEEKIKKALEKGEVLPTEARFDSNCITPGTDFMARLQEQLKYFVHNKLSTDKTWQGVNVYLSGHETPGEGEHKIMEFIRSESTKPGHNPNTRHCLYGLDADLIMLGLTSHEPHFSLLREEVRFGGKKSQKRITAPEETTFHLLHLSLMREYIDYEFSELRKKISFEYDLERIIDDWVLMGFLVGNDFIPHLPHLHINHDALPLLYRTYINVLPSLGGYLNENGHLNLTHFEKYLEKLSDFDREHFSEVFVDLKWFESKVGNKYVNEAAGLAAEEADGRDLKKSKSSDDSLCLAALDGVRDSHSTAGRAEGAEEDGEDDDMFETEFRQYKRTYYMTKMGVEVVSDEFLANQAKCYVEGIQWILHYYYHGVQSWSWYYPYHYAPFLSDVRNISGLSLTFDLAKPFMPFEQLLAVLPSASKDLLPQCYQHLMTSLSSPIVEYYPQDFKTDLNGKQQEWEAVVLIPFIDEKCLLAAMEPYTHNLTPSEKARNRHTECAVYCYDKDLDYPYNSPDPQIFPNIVHCHARQTPVPMDAWRVSPDHVRCRIDRGALYFCGFPTLQHIRHKFYKKKSGVMVFQQSSRGENMILDILPSHEMVQVEEVAALVLGRSLFVNWPHLMEARVVAVSDGETKFSLEEPAGSQVLYMENNPPPTKVSRVTDKEQKDWVKEVQGLTEHFSKRKGIAINETDVLVYGQLLTGRKYVIGQNGKVHLEKQFAKQVLPFPYQTIVKDIKAFDSSLARFKTLEELFPLGTTVFMVGNPYYGAMGEVQDSSDVISEGRVRVVFSVPCEPQLDALIQNQHKYSVKYSPGYVLASRLGITGYLVSRFSGSIFIGRGSKKNPHGEQKVNVGLNLKFNKKNEEVPGYTKRTEKEWLYSAAVEELIAEYLERFSEVFDHVARNSHDDIFYEDDIWPGEDENGVEKVQEIQGWLKTHPVSSISRASCDLQILDAGIVEKIEEELEKTKAKKMNKKVRVTVKPHLLFRPLEQQHGVVPDPDSEYHLFDRVVNVRESFSVPLGLRGTIIGIKGADREAEILYEVIFDEEFAGGLTIRCSPGRGYRLPPSALINLSHGSRKELGSHKLTAIVKPQPSSSSQISNKSQLGGLNHSPRSPFIPTQQQNGRQSFNLRGDTQGNRNSPHKALNQRNQQKGSSNEKEFSNVWQSLQNSAMPQKPPAHWQNNAGKSQMPHQNQLEGQNKQSQGNDTSIKLGLGGNIRLLKRNEDLNTALQGPSNKASTEFEELIANLKISKDPEPPQHEPPKEPKAPSAEPLSPQSFAMKGTLVLKEMLKIDSSGASSSAPDSGGPNAQQQCKRRSSKKLAARINTPQPETAPAAAAAPPPPPPPHPLAGQPPLLPSMATELGRVCMGLRMGPPEFAFLRNRQSLILCQVKLSNGLMVHGPQCQSETEAKEKAALFTLQRLNSLGSFPLPPPIFPGVQQMRPLAPHPSMFGQPGGGFLMPPQGYGPLPWGMQFPHQGQPFFGGTFPGARGPVPSAAGGSHNQFVPLQVTKKRVSGRTKNQESNQAQSGSPYGVQTPAVPPSAPKTPPSTNAHEHAEKPTATTPKTPKQNANPHTPGSASKRKHRKLAVNFEAAKVTD", "length": 1697 }, "evidence": [ { "id": "A0A8V0YLM3", "url": "https://omabrowser.org/oma/group/A0A8V0YLM3/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "P22147-1", "protein_name": "5'-3' exoribonuclease 1", "gene_name": "XRN1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MGIPKFFRYISERWPMILQLIEGTQIPEFDNLYLDMNSILHNCTHGNDDDVTKRLTEEEVFAKICTYIDHLFQTIKPKKIFYMAIDGVAPRAKMNQQRARRFRTAMDAEKALKKAIENGDEIPKGEPFDSNSITPGTEFMAKLTKNLQYFIHDKISNDSKWREVQIIFSGHEVPGEGEHKIMNFIRHLKSQKDFNQNTRHCIYGLDADLIMLGLSTHGPHFALLREEVTFGRRNSEKKSLEHQNFYLLHLSLLREYMELEFKEIADEMQFEYNFERILDDFILVMFVIGNDFLPNLPDLHLNKGAFPVLLQTFKEALLHTDGYINEHGKINLKRLGVWLNYLSQFELLNFEKDDIDVEWFNKQLENISLEGERKRQRVGKKLLVKQQKKLIGSIKPWLMEQLQEKLSPDLPDEEIPTLELPKDLDMKDHLEFLKEFAFDLGLFITHSKSKGSYSLKMDLDSINPDETEEEFQNRVNSIRKTIKKYQNAIIVEDKEELETEKTIYNERFERWKHEYYHDKLKFTTDSEEKVRDLAKDYVEGLQWVLYYYYRGCPSWSWYYPHHYAPRISDLAKGLDQDIEFDLSKPFTPFQQLMAVLPERSKNLIPPAFRPLMYDEQSPIHDFYPAEVQLDKNGKTADWEAVVLISFVDEKRLIEAMQPYLRKLSPEEKTRNQFGKDLIYSFNPQVDNLYKSPLGGIFSDIEHNHCVEKEYITIPLDSSEIRYGLLPNAKLGAEMLAGFPTLLSLPFTSSLEYNETMVFQQPSKQQSMVLQITDIYKTNNVTLEDFSKRHLNKVIYTRWPYLRESKLVSLTDGKTIYEYQESNDKKKFGFITKPAETQDKKLFNSLKNSMLRMYAKQKAVKIGPMEAIATVFPVTGLVRDSDGGYIKTFSPTPDYYPLQLVVESVVNEDERYKERGPIPIEEEFPLNSKVIFLGDYAYGGETTIDGYSSDRRLKITVEKKFLDSEPTIGKERLQMDHQAVKYYPSYIVSKNMHLHPLFLSKITSKFMITDATGKHINVGIPVKFEARHQKVLGYARRNPRGWEYSNLTLNLLKEYRQTFPDFFFRLSKVGNDIPVLEDLFPDTSTKDAMNLLDGIKQWLKYVSSKFIAVSLESDSLTKTSIAAVEDHIMKYAANIEGHERKQLAKVPREAVLNPRSSFALLRSQKFDLGDRVVYIQDSGKVPIFSKGTVVGYTTLSSSLSIQVLFDHEIVAGNNFGGRLRTNRGLGLDASFLLNITNRQFIYHSKASKKALEKKKQSNNRNNNTKTAHKTPSKQQSEEKLRKERAHDLLNFIKKDTNEKNSESVDNKSMGSQKDSKPAKKVLLKRPAQKSSENVQVDLANFEKAPLDNPTVAGSIFNAVANQYSDGIGSNLNIPTPPHPMNVVGGPIPGANDVADVGLPYNIPPGFMTHPNGLHPLHPHQMPYPNMNGMSIPPPAPHGFGQPISFPPPPPMTNVSDQGSRIVVNEKESQDLKKFINGKQHSNGSTIGGETKNSRKGEIKPSSGTNSTECQSPKSQSNAADRDNKKDEST", "length": 1528 }, "evidence": [ { "id": "A0A8V0YLM3", "url": "https://omabrowser.org/oma/group/A0A8V0YLM3/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P97789-1", "protein_name": "5'-3' exoribonuclease 1", "gene_name": "Xrn1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGVPKFYRWISERYPCLSEVVKEHQIPEFDNLYLDMNGIIHQCSHPNDDDVHFRISDDKIFTDIFHYLEVLFRIIKPRKVFFMAVDGVAPRAKMNQQRGRRFRSAKEAEDKIKKAIEKGETLPTEARFDSNCITPGTEFMARLHEHLKYFVNMKISTDKSWQGVTIYFSGHETPGEGEHKIMEFIRSEKAKPDHDPNTRHCLYGLDADLIMLGLTSHEAHFSLLREEVRFGGKKTQRVCAPEETTFHLLHLSLMREYIDYEFSALKEKITFKYDIEKIIDDWILMGFLVGNDFIPHLPHLHINHDALPLLYGTYIAILPELGGYINESGHLNLPRFERYLVKLSDFDREHFSEVFVDLKWFESKVGNKYLNEAAGAAAEEAKNCKEKRKPKGQENSLSWAALDKSEGEGVASRDNFEDETEDDDLFETEFRQYKRTYYMTKMGVDVVSDEFLANQAACYVQAIQWILHYYYHGVQSWSWYYPYHYAPFLSDIRSISTLKIHFELGKPFKPFEQLLAVLPSASKNLLPTCYQHLMTSEDSPIIEYYPPDFKTDLNGKQQEWEAVVLIPFIDETRLLEAMETCNHSLKKEERKRNQHSECLMCWYDRDTEFTYSSPWPEKFPAIERCCTRYKMISLDAWRVDINKNKITRVDQKALYFCGFPTLKHIKHKFFLKKSGVQVFQQSSRGENLMLEISVNAEPDELRIENIASAVLGKAVFVNWPHLEEARVVAVSDGETKFYIEEPPGTQKVYLGKTAPPSKVIQLTDKEQSNWTKEIQGISEQYLRRKGIIINETSAVVYAQLLTGRKYQISQNGEVRLEKQWSKQILPFVYQTIVKDIRAFDSRFSNIKTLDDLFPPRTMVFMLGTPYYGCTGEVQDSGDLITEGRIRVVFSIPCEPNLDALIQNQHKYSIKYNPGYVLAGRLGVSGYLVSRFTGSIFIGRGSRRNPHGDHKANVGLNLKFNKKNEEVPGYTKKVGNEWMYSSAAEQLLAEYIERAPELFSYIAKNSQEDVFYEDDIWPGENENGAEKVQEIITWLKGHPVSTLSRSSCDLHILDAAIVEKIEEEVEKCKQRKSNKKVRVTVKPHLMYRPLEQQHGVIPDRDAEFRLFDRVVNVRESFSVPVGLRGTVIGIKGASREADVLFEVLFDEEFPGGLTIRCSPGRGYRLPTSALVNLSHGSRCETGNQKLTAIVKPQPSVSHCSAAPSGHLGGLNHSPQSPFLPTQVPTKGDDEFCNIWQSLQGAGKTQHLQPTVQEKGAVLPQEISQVTEGHKSGFTDHSVRHQQRKHDSQRKFKEEYKSPKAECQSQKLSSKQTSGGSARCSIKLLKRNESPGTSEAQKVVTSYPNAVHKPPSGIENFLASLNLSKENEAQLPHHGEPPDEADLSPQSFAMKGTRMLKEILKIDSPDTRDSKNDMKKSDNEATVSSRRDERGVSAHPKPTCHMNKPHGTNEFQNVASVDSVCWPGQMPPVSTPVTELSRICSLVGMPQPDFSFLRTTQTMTVCQVKLSNGLLVHGPQCHSESEAKERAALFALQQLGSLGVSFPLPPPIFTNYPPAVPPGAVPPVFTQPTANIMPSSSHLFGSVSWRPPVPVAGNAFHYPSYPGTMPLAGGVPGGVHSQFIPLQVTKKRVANRKNFENKEAQSSQATPLQTNKPGSSEATKMTPQESPPASSSSSQAAQPVSSHVETASQGHVGSQPRSAPSSSKRKSRKLAVNFSVSKPSE", "length": 1719 }, "evidence": [ { "id": "A0A8V0YLM3", "url": "https://omabrowser.org/oma/group/A0A8V0YLM3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8IZH2-1", "protein_name": "5'-3' exoribonuclease 1", "gene_name": "XRN1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGVPKFYRWISERYPCLSEVVKEHQIPEFDNLYLDMNGIIHQCSHPNDDDVHFRISDDKIFTDIFHYLEVLFRIIKPRKVFFMAVDGVAPRAKMNQQRGRRFRSAKEAEDKIKKAIEKGETLPTEARFDSNCITPGTEFMARLHEHLKYFVNMKISTDKSWQGVTIYFSGHETPGEGEHKIMEFIRSEKAKPDHDPNTRHCLYGLDADLIMLGLTSHEAHFSLLREEVRFGGKKTQRVCAPEETTFHLLHLSLMREYIDYEFSVLKEKITFKYDIERIIDDWILMGFLVGNDFIPHLPHLHINHDALPLLYGTYVTILPELGGYINESGHLNLPRFEKYLVKLSDFDREHFSEVFVDLKWFESKVGNKYLNEAAGVAAEEARNYKEKKKLKGQENSLCWTALDKNEGEMITSKDNLEDETEDDDLFETEFRQYKRTYYMTKMGVDVVSDDFLADQAACYVQAIQWILHYYYHGVQSWSWYYPYHYAPFLSDIHNISTLKIHFELGKPFKPFEQLLAVLPAASKNLLPACYQHLMTNEDSPIIEYYPPDFKTDLNGKQQEWEAVVLIPFIDEKRLLEAMETCNHSLKKEERKRNQHSECLMCWYDRDTEFIYPSPWPEKFPAIERCCTRYKIISLDAWRVDINKNKITRIDQKALYFCGFPTLKHIRHKFFLKKSGVQVFQQSSRGENMMLEILVDAESDELTVENVASSVLGKSVFVNWPHLEEARVVAVSDGETKFYLEEPPGTQKLYSGRTAPPSKVVHLGDKEQSNWAKEVQGISEHYLRRKGIIINETSAVVYAQLLTGRKYQINQNGEVRLEKQWSKQVVPFVYQTIVKDIRAFDSRFSNIKTLDDLFPLRSMVFMLGTPYYGCTGEVQDSGDVITEGRIRVIFSIPCEPNLDALIQNQHKYSIKYNPGYVLASRLGVSGYLVSRFTGSIFIGRGSRRNPHGDHKANVGLNLKFNKKNEEVPGYTKKVGSEWMYSSAAEQLLAEYLERAPELFSYIAKNSQEDVFYEDDIWPGENENGAEKVQEIITWLKGHPVSTLSRSSCDLQILDAAIVEKIEEEVEKCKQRKNNKKVRVTVKPHLLYRPLEQQHGVIPDRDAEFCLFDRVVNVRENFSVPVGLRGTIIGIKGANREADVLFEVLFDEEFPGGLTIRCSPGRGYRLPTSALVNLSHGSRSETGNQKLTAIVKPQPAVHQHSSSSSVSSGHLGALNHSPQSLFVPTQVPTKDDDEFCNIWQSLQGSGKMQYFQPTIQEKGAVLPQEISQVNQHHKSGFNDNSVKYQQRKHDPHRKFKEECKSPKAECWSQKMSNKQPNSGIENFLASLNISKENEVQSSHHGEPPSEEHLSPQSFAMGTRMLKEILKIDGSNTVDHKNEIKQIANEIPVSSNRRDEYGLPSQPKQNKKLASYMNKPHSANEYHNVQSMDNMCWPAPSQIPPVSTPVTELSRICSLVGMPQPDFSFLRMPQTMTVCQVKLSNGLLVHGPQCHSENEAKEKAALFALQQLGSLGMNFPLPSQVFANYPSAVPPGTIPPAFPPPTGWDHYGSNYALGAANIMPSSSHLFGSMPWGPSVPVPGKPFHHTLYSGTMPMAGGIPGGVHNQFIPLQVTKKRVANKKNFENKEAQSSQATPVQTSQPDSSNIVKVSPRESSSASLKSSPIAQPASSFQVETASQGHSISHHKSTPISSSRRKSRKLAVNFGVSKPSE", "length": 1706 }, "evidence": [ { "id": "A0A8V0YLM3", "url": "https://omabrowser.org/oma/group/A0A8V0YLM3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "nuclear mRNA surveillance", "id": "GO:0071028", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071028", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLM3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLM3" } ], "pmid": "" }, { "name": "nuclear-transcribed mRNA catabolic process", "id": "GO:0000956", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000956", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLM3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLM3" } ], "pmid": "" }, { "name": "rRNA catabolic process", "id": "GO:0016075", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016075", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLM3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLM3" } ], "pmid": "" }, { "name": "histone mRNA catabolic process", "id": "GO:0071044", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071044", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLM3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLM3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLM3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLM3" } ], "pmid": "" }, { "name": "5'-3' RNA exonuclease activity", "id": "GO:0004534", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004534", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLM3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLM3" } ], "pmid": "" }, { "name": "telomerase RNA binding", "id": "GO:0070034", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070034", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLM3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLM3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLM3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLM3" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLM3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLM3" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLM3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLM3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1114, "end_pos": 1116, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1170, "end_pos": 1172, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1218, "end_pos": 1220, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1371, "end_pos": 1373, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1655, "end_pos": 1657, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1744, "end_pos": 1746, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1749, "end_pos": 1751, "annotation": "n_glycosylation_sequon" }, { "start_pos": 493, "end_pos": 495, "annotation": "n_glycosylation_sequon" }, { "start_pos": 649, "end_pos": 651, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YLM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLM3" }, { "id": "PF18332", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18332" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "5'-3' exoribonuclease 1 D1", "eco_id": "ECO_0000259", "start_pos": 655, "end_pos": 843, "start_aa": "Phe", "end_aa": "Ser", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0YLM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLM3" }, { "id": "PF18129", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18129" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "5'-3' exoribonuclease 1 SH3-like", "eco_id": "ECO_0000259", "start_pos": 1101, "end_pos": 1170, "start_aa": "Glu", "end_aa": "Asn", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0YLM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLM3" }, { "id": "PF18334", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18334" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Exoribonuclease Xrn1 D2/D3", "eco_id": "ECO_0000259", "start_pos": 849, "end_pos": 1074, "start_aa": "Asp", "end_aa": "Lys", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0YLM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLM3" }, { "id": "PF03159", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03159" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Xrn1 N-terminal", "eco_id": "ECO_0000259", "start_pos": 1, "end_pos": 227, "start_aa": "Met", "end_aa": "Glu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0YLM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLM3" }, { "id": "PF17846", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17846" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Xrn1 helical", "eco_id": "ECO_0000259", "start_pos": 273, "end_pos": 604, "start_aa": "Tyr", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 1500 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1114, "end_pos": 1116 }, { "start_pos": 1170, "end_pos": 1172 }, { "start_pos": 1218, "end_pos": 1220 }, { "start_pos": 1371, "end_pos": 1373 }, { "start_pos": 1655, "end_pos": 1657 }, { "start_pos": 1744, "end_pos": 1746 }, { "start_pos": 1749, "end_pos": 1751 }, { "start_pos": 493, "end_pos": 495 }, { "start_pos": 649, "end_pos": 651 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 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"XP_003642960", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003642960" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052572.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_003642960.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003642960", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003642960" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLN5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLN5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ARSB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLN5", "locus": { "chromosome": "Z", "start_pos": 23110528, "end_pos": 23041861, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013306", "url": "https://www.ensembl.org/id/ENSGALG00010013306" } ] } } ], "crossref": [ { "id": "A0A8V0YLN5", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YLN5", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd16029", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16029", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "771459", "url": "https://www.ncbi.nlm.nih.gov/gene/771459", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000917", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000917", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017850", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017850", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024607", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024607", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047115", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047115", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:771459", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:771459", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HEHCVFI", "url": "https://omabrowser.org/oma/group/HEHCVFI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YLN5", "url": "https://www.orthodb.org/?gene=A0A8V0YLN5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YRK6", "url": "https://www.orthodb.org/?gene=A0A8V0YRK6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10342", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10342", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10342:SF274", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10342:SF274", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00884", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00884", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-1663150", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1663150", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-2024101", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2024101", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-6798695", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6798695", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9840310", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9840310", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_003642960", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003642960", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YLN5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLN5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLN5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLN5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YRK6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRK6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YRK6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRK6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MERLRALWCLLWCLLRPAAARPPPHLVLVLADDLGWGDVGWHGSAIRTPRLDALGAGGVRLERYYTQPLCTPSRSQLLSGRYQIHTGLQHQIIWPCQPSCLPLDEKLLPELLKDAGYVTHMVGKWHLGMYRKECLPTRRGFDTYFGYLLGSEDYYSHDHCVLIKAKNVTRCALDFRDGEEVATGFKNMYSTNLFTERAIDLIANHKTEKPLFLYLAFQSVHEPLEVSAEYMKPYSSIKDVKRRRYAGMVSLMDEAVGNLTDALKEYGLWNNTVLVFSTDNGGQTMAGGNNWPLRGRKWTLWEGGVRGVGFVASPLLKQKGVESHELIHISDWLPTLVHLAGGHTNGTKPLDGFDVWKTISEGRPSPRVELLHNIDPMFVDDYPCLGIDNRTSLPQTNSFPWDNTLFNISVHAAIRHGKWKLLTGYPGCGHWFPPPSLSSESQIQSYDPPMKRLWLFDIVRDPEEKYELSEKYPHVVKKLLSRLQYYYKRSVPVFYPDEDPQCDPAATGVWGPWA", "length": 514, "header": "tr|A0A8V0YLN5-1|A0A8V0YLN5_CHICK Isoform 1 of Arylsulfatase B OS=Gallus gallus OX=9031 GN=ARSB PE=1 SV=1 CANONICAL=A0A8V0YLN5-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YLN5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLN5/entry#A0A8V0YLN5-1", "sequence": { "sequence": "MERLRALWCLLWCLLRPAAARPPPHLVLVLADDLGWGDVGWHGSAIRTPRLDALGAGGVRLERYYTQPLCTPSRSQLLSGRYQIHTGLQHQIIWPCQPSCLPLDEKLLPELLKDAGYVTHMVGKWHLGMYRKECLPTRRGFDTYFGYLLGSEDYYSHDHCVLIKAKNVTRCALDFRDGEEVATGFKNMYSTNLFTERAIDLIANHKTEKPLFLYLAFQSVHEPLEVSAEYMKPYSSIKDVKRRRYAGMVSLMDEAVGNLTDALKEYGLWNNTVLVFSTDNGGQTMAGGNNWPLRGRKWTLWEGGVRGVGFVASPLLKQKGVESHELIHISDWLPTLVHLAGGHTNGTKPLDGFDVWKTISEGRPSPRVELLHNIDPMFVDDYPCLGIDNRTSLPQTNSFPWDNTLFNISVHAAIRHGKWKLLTGYPGCGHWFPPPSLSSESQIQSYDPPMKRLWLFDIVRDPEEKYELSEKYPHVVKKLLSRLQYYYKRSVPVFYPDEDPQCDPAATGVWGPWA", "length": 514, "header": "tr|A0A8V0YLN5-1|A0A8V0YLN5_CHICK Isoform 1 of Arylsulfatase B OS=Gallus gallus OX=9031 GN=ARSB PE=1 SV=1 CANONICAL=A0A8V0YLN5-1" }, "locus": { "chromosome": "Z", "start_pos": 23107701, "end_pos": 23041886, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032017.1", "url": "https://www.ensembl.org/id/ENSGALT00010032017.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018807.1", "url": "https://www.ensembl.org/id/ENSGALP00010018807.1" } ] } }, { "isoform_ac": "A0A8V0YRK6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLN5/entry#A0A8V0YRK6-1", "sequence": { "sequence": "MARPSGRRGWTRWGRAACGWSATTRSRCARRPAASSSAAATRQASKRGKREEKERERGKKKKKEGKKSKPPLQILGCPIHTGLQHQIIWPCQPSCLPLDEKLLPELLKDAGYVTHMVGKWHLGMYRKECLPTRRGFDTYFGYLLGSEDYYSHDHCVLIKAKNVTRCALDFRDGEEVATGFKNMYSTNLFTERAIDLIANHKTEKPLFLYLAFQSVHEPLEVSAEYMKPYSSIKDVKRRRYAGMVSLMDEAVGNLTDALKEYGLWNNTVLVFSTDNGGQTMAGGNNWPLRGRKWTLWEGGVRGVGFVASPLLKQKGVESHELIHISDWLPTLVHLAGGHTNGTKPLDGFDVWKTISEGRPSPRVELLHNIDPMFVDDYPCLGIDNRTSLPQTNSFPWDNTLFNISVHAAIRHGKWKLLTGYPGCGHWFPPPSLSSESQIQSYDPPMKRLWLFDIVRDPEEKYELSEKYPHVVKKLLSRLQYYYKRSVPVFYPDEDPQCDPAATGVWGPWA", "length": 509, "header": "tr|A0A8V0YRK6-1|A0A8V0YRK6_CHICK Computationally mapped isoform of Arylsulfatase B OS=Gallus gallus OX=9031 GN=ARSB PE=1 SV=1 CANONICAL=A0A8V0YLN5-1" }, "locus": { "chromosome": "Z", "start_pos": 23107701, "end_pos": 23042010, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032010.1", "url": "https://www.ensembl.org/id/ENSGALT00010032010.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018800.1", "url": "https://www.ensembl.org/id/ENSGALP00010018800.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:771459", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:771459", "resource": "KEGG Pathway" }, { "id": "R-GGA-1663150", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1663150", "resource": "Reactome", "description": "The activation of arylsulfatases" }, { "id": "R-GGA-2024101", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2024101", "resource": "Reactome", "description": "CS/DS degradation" }, { "id": "R-GGA-6798695", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6798695", "resource": "Reactome", "description": "Neutrophil degranulation" }, { "id": "R-GGA-9840310", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9840310", "resource": "Reactome", "description": "Glycosphingolipid catabolism" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287A1K2-1", "protein_name": "Arylsulfatase B", "gene_name": "ARSB", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGRRGAESWPRGPGQRRPLLPTVLPLGLLLLLLPPLGSSIGAGRPPHLVFVLADDLGWNDVGFHGSEIRTPHLDALAAGGVLLDNYYTQPLCTPSRSQLLTGRYQIHTGLQHQIIWPCQPSCIPLDEKLLPQLLKEAGYATHMVGKWHLGMYRKECLPTRRGFDTYFGYLLGSEDYYSHERCTLINALNVTRCALDFRDGEEVATGYKNMYSTNVFTERATALITNHPPEKPLFLYLALQSVHEPLQVPEEYLKPYDFIQNKNRHYYAGMVSLMDEAVGNVTAALKSRGLWNNTVFIFSTDNGGQTLAGGNNWPLRGRKWSLWEGGVRGVGFVAGPLLKRKGVKNRELIHISDWLPTLVKLAGGSTHGTKPLDGFDVWKTISEGSPSPRMELLHNIDPNFVDVSPCLGNSTAPAKDDFSLPEHSAFNTSVHAAIRYRNWKLLTGYPGCGHWFPPPSQYNVSEIPSSDPPTKTTWLFDLERDPEERHDLSRDHPHIVQLLLTRLQFYQKHSVPVYFPAQDPRCDPKATGAWGPWM", "length": 534 }, "evidence": [ { "id": "A0A8V0YLN5", "url": "https://omabrowser.org/oma/group/A0A8V0YLN5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P15848-1", "protein_name": "Arylsulfatase B", "gene_name": "ARSB", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGPRGAASLPRGPGPRRLLLPVVLPLLLLLLLAPPGSGAGASRPPHLVFLLADDLGWNDVGFHGSRIRTPHLDALAAGGVLLDNYYTQPLCTPSRSQLLTGRYQIRTGLQHQIIWPCQPSCVPLDEKLLPQLLKEAGYTTHMVGKWHLGMYRKECLPTRRGFDTYFGYLLGSEDYYSHERCTLIDALNVTRCALDFRDGEEVATGYKNMYSTNIFTKRAIALITNHPPEKPLFLYLALQSVHEPLQVPEEYLKPYDFIQDKNRHHYAGMVSLMDEAVGNVTAALKSSGLWNNTVFIFSTDNGGQTLAGGNNWPLRGRKWSLWEGGVRGVGFVASPLLKQKGVKNRELIHISDWLPTLVKLARGHTNGTKPLDGFDVWKTISEGSPSPRIELLHNIDPNFVDSSPCPRNSMAPAKDDSSLPEYSAFNTSVHAAIRHGNWKLLTGYPGCGYWFPPPSQYNVSEIPSSDPPTKTLWLFDIDRDPEERHDLSREYPHIVTKLLSRLQFYHKHSVPVYFPAQDPRCDPKATGVWGPWM", "length": 533 }, "evidence": [ { "id": "A0A8V0YLN5", "url": "https://omabrowser.org/oma/group/A0A8V0YLN5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P50429-1", "protein_name": "Arylsulfatase B", "gene_name": "Arsb", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGKLSPCTGRSRPGGPGPQLPLLLLLLQLLLLLLSPARASGATQPPHVVFVLADDLGWNDLGFHGSVIRTPHLDALAAGGVVLDNYYVQPLCTPSRSQLLTGRYQIHLGLQHYLIMTCQPSCVPLDEKLLPQLLKEAGYATHMVGKWHLGMYRKECLPTRRGFDTYFGYLLGSEDYYTHEACAPIESLNGTRCALDLRDGEEPAKEYNNIYSTNIFTKRATTVIANHPPEKPLFLYLAFQSVHDPLQVPEEYMEPYGFIQDKHRRIYAGMVSLMDEAVGNVTKALKSHGLWNNTVFIFSTDNGGQTRSGGNNWPLRGRKGTLWEGGIRGTGFVASPLLKQKGVKSRELMHITDWLPTLVDLAGGSTNGTKPLDGFNMWKTISEGHPSPRVELLHNIDQDFFDGLPCPGKNMTPAKDDSFPLEHSAFNTSIHAGIRYKNWKLLTGHPGCGYWFPPPSQSNVSEIPPVGPPTKTLWLFDINQDPEERHDVSREHPHIVQNLLSRLQYYHEHSVPSHFPPLDPRCDPKSTGVWSPWM", "length": 534 }, "evidence": [ { "id": "A0A8V0YLN5", "url": "https://omabrowser.org/oma/group/A0A8V0YLN5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P50430-1", "protein_name": "Arylsulfatase B", "gene_name": "Arsb", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGELSGCTGGSRAGGPGPRLPLLLLLLLWPARASDAAPPPHVVFVLADDLGWNDLGFHGSVIRTPHLDALAAGGVVLDNYYVQPLCTPSRSQLLTGRYQIHMGLQHYLIMTCQPNCVPLDEKLLPQLLKDAGYATHMVGKWHLGMYRKECLPTRRGFDTYFGYLLGSEDYYTHEACAPIECLNGTRCALDLRDGEEPAKEYTDIYSTNIFTKRATTLIANHPPEKPLFLYLAFQSVHDPLQVPEEYMEPYDFIQDKHRRIYAGMVSLLDEAVGNVTKALKSRGLWNNTVLIFSTDNGGQTRSGGNNWPLRGRKGTLWEGGIRGAGFVASPLLKQKGVKSRELMHITDWLPTLVNLAGGSTHGTKPLDGFDVWETISEGSPSPRVELLLNIDPDFFDGLPCPGKNTTPEKNDSFPLEHSAFNTSIHAGIRYKNWKLLTGYPGCGYWFPPPSQSNISEVPSVDSPTKTLWLFDINRDPEERHDVSREHPHIVQNLLSRLQYYHEHSVPSYFPPLDPRCDPKGTGVWSPWM", "length": 528 }, "evidence": [ { "id": "A0A8V0YLN5", "url": "https://omabrowser.org/oma/group/A0A8V0YLN5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLN5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLN5" } ], "pmid": "" }, { "name": "N-acetylgalactosamine-4-sulfatase activity", "id": "GO:0003943", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003943", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLN5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLN5" } ], "pmid": "" }, { "name": "sulfuric ester hydrolase activity", "id": "GO:0008484", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008484", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLN5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLN5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "regulation of epithelial cell migration", "id": "GO:0010632", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010632", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLN5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLN5" } ], "pmid": "" }, { "name": "chondroitin sulfate proteoglycan catabolic process", "id": "GO:0030207", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030207", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLN5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLN5" } ], "pmid": "" }, { "name": "colon epithelial cell migration", "id": "GO:0061580", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061580", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLN5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLN5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 167, "end_pos": 169, "annotation": "n_glycosylation_sequon" }, { "start_pos": 258, "end_pos": 260, "annotation": "n_glycosylation_sequon" }, { "start_pos": 270, "end_pos": 272, "annotation": "n_glycosylation_sequon" }, { "start_pos": 345, "end_pos": 347, "annotation": "n_glycosylation_sequon" }, { "start_pos": 389, "end_pos": 391, "annotation": "n_glycosylation_sequon" }, { "start_pos": 407, "end_pos": 409, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YLN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLN5" }, { "id": "PF00884", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00884" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Sulfatase N-terminal", "eco_id": "ECO_0000259", "start_pos": 24, "end_pos": 341, "start_aa": "Pro", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 167, "end_pos": 169 }, { "start_pos": 258, "end_pos": 260 }, { "start_pos": 270, "end_pos": 272 }, { "start_pos": 345, "end_pos": 347 }, { "start_pos": 389, "end_pos": 391 }, { "start_pos": 407, "end_pos": 409 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YLP9-1", "uniprot_ac": "A0A8V0YLP9", "uniprot_id": "A0A8V0YLP9_CHICK", "mass": { "chemical_mass": 45643.0, "monoisotopic_mass": 45643.0 }, "refseq": { "ac": "XP_015153053", "name": "UBX domain-containing protein 11 isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015153053" }, "gene_names": [ { "name": "UBXN11", "type": "recommended", "evidence": [ { "id": "A0A8V0YLP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLP9" } ] }, { "name": "UBXN11", "type": "synonym", "evidence": [ { "id": "XP_015153053", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015153053" } ] } ], "protein_names": [ { "name": "UBX domain-containing protein 11", "type": "recommended", "evidence": [ { "id": "A0A8V0YLP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLP9/entry#names_and_taxonomy" } ] }, { "name": "Socius", "type": "synonym", "evidence": [ { "id": "A0A8V0YLP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLP9/entry#names_and_taxonomy" } ] }, { "name": "UBX domain-containing protein 11 isoform X3", "type": "synonym", "evidence": [ { "id": "XP_015153053", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015153053" } ] }, { "name": "UBX domain-containing protein 5", "type": "synonym", "evidence": [ { "id": "A0A8V0YLP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLP9/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052554.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015153053.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015153053", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015153053" } ] }, { "annotation": "May be involved in the reorganization of actin cytoskeleton mediated by RND1, RND2 and RND3. Promotes RHOA activation mediated by GNA12 and GNA13.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLP9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLP9#function" }, { "database": "UniProtKB", "id": "ARBA00059434", "url": "https://www.uniprot.org/uniprotkb/ARBA00059434#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLP9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLP9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "UBXN11", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLP9", "locus": { "chromosome": "23", "start_pos": 590454, "end_pos": 580074, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013315", "url": "https://www.ensembl.org/id/ENSGALG00010013315" } ] } } ], "crossref": [ { "id": "A0A8V0YLP9", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YLP9", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd17077", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd17077", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "419546", "url": "https://www.ncbi.nlm.nih.gov/gene/419546", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000626", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000626", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001012", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001012", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029071", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029071", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036241", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036241", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:419546", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419546", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DFELMSA", "url": "https://omabrowser.org/oma/group/DFELMSA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YLP9", "url": "https://www.orthodb.org/?gene=A0A8V0YLP9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23333", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23333", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23333:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23333:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00789", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00789", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08059", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08059", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-9696264", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9696264", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9696270", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9696270", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_015153053", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015153053", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YLP9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLP9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLP9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLP9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MELMSSMMQKISLLEQKIDKQAQEIQLKDRKIAELEEKMKTLQKGEDAPDSSTAEDLETRCLQLQTQVWEMERFLNDYGLVWVGDRHEEQEDLESLRDDELLAKRKPGEAVVSKHQVDFDLILENVKSLNMLAGDCISHIEHTPGGARLRQPEPLPLTLYQNGIVMLDGPFRSYEELSVQQCLQDIMDGYFPSELQARYPDGVPLQVTDKRDVVFQERDLPGSFPGHGQVVGHSKLSKVEEPAKIPGPKPSLEQFWNKYSKSSMHSEAMATRDTVGAMQQGSDGVWSSKEIVVGTPRLSVLQRLETSEEAEASAPDVCTLRIKSESGEQMYVIKMLSSETIGDLRQHLAHARGGDSDSYEIISTFPQRVYADNSRSLQECGLIPNASLLLRRRDPFPPEGTALQTA", "length": 406, "header": "tr|A0A8V0YLP9-1|A0A8V0YLP9_CHICK Isoform 1 of UBX domain-containing protein 11 OS=Gallus gallus OX=9031 GN=UBXN11 PE=4 SV=1 CANONICAL=A0A8V0YLP9-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YLP9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLP9/entry#A0A8V0YLP9-1", "sequence": { "sequence": "MELMSSMMQKISLLEQKIDKQAQEIQLKDRKIAELEEKMKTLQKGEDAPDSSTAEDLETRCLQLQTQVWEMERFLNDYGLVWVGDRHEEQEDLESLRDDELLAKRKPGEAVVSKHQVDFDLILENVKSLNMLAGDCISHIEHTPGGARLRQPEPLPLTLYQNGIVMLDGPFRSYEELSVQQCLQDIMDGYFPSELQARYPDGVPLQVTDKRDVVFQERDLPGSFPGHGQVVGHSKLSKVEEPAKIPGPKPSLEQFWNKYSKSSMHSEAMATRDTVGAMQQGSDGVWSSKEIVVGTPRLSVLQRLETSEEAEASAPDVCTLRIKSESGEQMYVIKMLSSETIGDLRQHLAHARGGDSDSYEIISTFPQRVYADNSRSLQECGLIPNASLLLRRRDPFPPEGTALQTA", "length": 406, "header": "tr|A0A8V0YLP9-1|A0A8V0YLP9_CHICK Isoform 1 of UBX domain-containing protein 11 OS=Gallus gallus OX=9031 GN=UBXN11 PE=4 SV=1 CANONICAL=A0A8V0YLP9-1" }, "locus": { "chromosome": "23", "start_pos": 590361, "end_pos": 581569, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032033.1", "url": "https://www.ensembl.org/id/ENSGALT00010032033.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018823.1", "url": "https://www.ensembl.org/id/ENSGALP00010018823.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:419546", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419546", "resource": "KEGG Pathway" }, { "id": "R-GGA-9696264", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9696264", "resource": "Reactome", "description": "RND3 GTPase cycle" }, { "id": "R-GGA-9696270", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9696270", "resource": "Reactome", "description": "RND2 GTPase cycle" } ], "orthologs": [ { "uniprot_canonical_ac": "E1BHW8-1", "protein_name": "UBX domain-containing protein 11", "gene_name": "UBXN11", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSSPLASLGKTRRVPLQSEPVNPGRRGIKIYGNEDEVDMLNGAHGSEERISVPSCYGGIGAPVSRQVPVYNDSELVATLTRKLRDLERQVKAQTDEILSKTRKIQALEEMVETLEKHQGKVSLQRQEELETVCAKLQRQVGEMERFLGDYGLQWVGEPMDQEDSEDGERDWMTAKKFWKPGDSLVPPEVDFDRLLASLKDLSELVEDSDTQVMPVPDRVPHQTLEPIPLRLYRNGIVMFDGPFRPFHDPSTQRCLRDILDGFFPSELQRLYPDGVPFKVSDLRSQVYPEHGLDPFPGEGRVVGLQRIRKPLDSIEHSGSRMTAEKFLNRLPKFVIRQGEVIDIRGPIRDTLQNCCPLPVRIQEIVVETPALAAERVRSRESPESPAPLLSMLRIKSENGEQAFLLMMRPEDRVGDVRALLAQARAVEPSTFEIFSTFPPTVYNDDALTLQAAGLVPNATLLLRVRRASPPAPGPK", "length": 475 }, "evidence": [ { "id": "A0A8V0YLP9", "url": "https://omabrowser.org/oma/group/A0A8V0YLP9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1R1A5-1", "protein_name": "UBX domain-containing protein 11", "gene_name": "ubxn11", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTSPLSILRKNRRAPLPDLHTDGERKPHKERSDSDYEEKLFQDIFPQNQPVPRVPDHLSTLRSKFMQKKKAKAAVPSDFELMSSMMQKICHLERKVKTQAVDIEQKARRIAVLEEKLNILREAKVLEESASNENQDEGLVQFCLKLQKQVWEMENFLNDYGMIWVGGYEENQDERAESQLTGASSGRKRFEMNFDLVMQNVKELNLEAGEGESHVTAIPGGAKLTQKPPIPLWLYKNGIVMFNGPFRSYQDPTTQECMQDLMDGFFPSELQERFPNGVPFQVNDRREEEFIVRRPRAEFPGRGQTIDGGQQMMDSSEISSTIPKQSQIAGRKLSMEQFLRKLPETVVKAGKVISIRDSVKAHLLGLSDDAKSRSAIIVETSALQSSRECENDSSKSAKDVSTLRVKSEDGTDTFIIKMYFTETIGDLRQYLDVKRGPSAASYDIISAFPQRRYSDDTQTLLACGLTPNAALLLRAQAPAHRH", "length": 482 }, "evidence": [ { "id": "A0A8V0YLP9", "url": "https://omabrowser.org/oma/group/A0A8V0YLP9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q5T124-1", "protein_name": "UBX domain-containing protein 11", "gene_name": "UBXN11", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSSPLASLSKTRKVPLPSEPMNPGRRGIRIYGDEDEVDMLSDGCGSEEKISVPSCYGGIGAPVSRQVPASHDSELMAFMTRKLWDLEQQVKAQTDEILSKDQKIAALEDLVQTLRPHPAEATLQRQEELETMCVQLQRQVREMERFLSDYGLQWVGEPMDQEDSESKTVSEHGERDWMTAKKFWKPGDSLAPPEVDFDRLLASLQDLSELVVEGDTQVTPVPGGARLRTLEPIPLKLYRNGIMMFDGPFQPFYDPSTQRCLRDILDGFFPSELQRLYPNGVPFKVSDLRNQVYLEDGLDPFPGEGRVVGRQLMHKALDRVEEHPGSRMTAEKFLNRLPKFVIRQGEVIDIRGPIRDTLQNCCPLPARIQEIVVETPTLAAERERSQESPNTPAPPLSMLRIKSENGEQAFLLMMQPDNTIGDVRALLAQARVMDASAFEIFSTFPPTLYQDDTLTLQAAGLVPKAALLLRARRAPKSSLKFSPGPCPGPGPGPSPGPGPGPSPGPGPGPSPCPGPSPSPQ", "length": 520 }, "evidence": [ { "id": "A0A8V0YLP9", "url": "https://omabrowser.org/oma/group/A0A8V0YLP9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8R512-1", "protein_name": "UBX domain-containing protein 11", "gene_name": "Ubxn11", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSSPLASLSKTRKVPLESEPVNPGRRGIRIYGDEDEVDMVNDGQDSEEKISLPSCYGGIGRQGLMIHDSELLTSMARKLQELEQQLKARNEEMLSKEQKILALEDLVQTLQQHQSSTTREEELETQCIQLQRQVGEMERFLNDYGLQWVGEPMDQENSEGKIISESDERDWMKAKKFWKPGDSIVPPEVDFDRLLSSLQDLSELVVEGEAQVTPVPGGAQFRTLEPIPLKLYRNGIMMFDGPFRPFYDPYTQRCLRDILDGFFPSELQRLYPDGVPFKVSDLRNQVYPEDGLGPFPGEGRVVGRQKIRKVTDRVEETSGSRMTAEKFLNRLPKCVIRQGEVIDIRGPIRDTLQNCCPMPVRIQEIIVETPALASERQRTQESPNMPVPPLSMLRIKSENGEQAFLLMMRPEDTIGDVRNLLAQARDMDSAAFEILSTFPPTVYRDDTVTLQAAGLVPNATLLLRTRRVLPANPSFGTDSGPGSLP", "length": 485 }, "evidence": [ { "id": "A0A8V0YLP9", "url": "https://omabrowser.org/oma/group/A0A8V0YLP9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9D572-1", "protein_name": "UBX domain-containing protein 11", "gene_name": "Ubxn11", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSPLASLSKTRKVPLESESVNPGRRGIRVYGNEDEVDMWNDGQDSEEKISLPSCYGGIGAPVSRQGPHDSELMASMTRKLQELEQQLQAQNDEMLSKERKILDLEDLVQTLQQHQNNAALQRQEELETQCIQLQRQIGEMERFLSDYGLQWVGEPMDQENSEEKTVSENDERDWMKAKKFWKPGDSFVPPEVDFDKLMASLQDLSELVEGEAQVTPVPGGARFRTLEPIPLKVYRNGIMMFDGPFRPFYDPSTQRCLRDILDGFFPSELQRLYPDGVPFKVSDLRNQIYPEDGLGQFPGEGRVVGRQKMRKVTDRVEETSGSRMTAEQFLNRLPKCIIRQGEVIDIRGPIRDTLQNCCPMPARIQEIIVETPALASERQRSQESPDMPMPLLSMLRIKSENGEQAFLLMMWPEDTIGDVRKLLAQARDMDSAAFEILSTFPPTVYQDDTVTLQAAGLVPNATLLLRTRRALLSNPISRPGSLP", "length": 484 }, "evidence": [ { "id": "A0A8V0YLP9", "url": "https://omabrowser.org/oma/group/A0A8V0YLP9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLP9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLP9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "proteasome-mediated ubiquitin-dependent protein catabolic process", "id": "GO:0043161", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043161", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLP9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLP9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "ubiquitin binding", "id": "GO:0043130", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043130", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLP9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLP9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 385, "end_pos": 387, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YLP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLP9" }, { "id": "PS51399", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51399" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SEP", "eco_id": "ECO_0000259", "start_pos": 152, "end_pos": 216, "start_aa": "Pro", "end_aa": "Gln", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0YLP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLP9" }, { "id": "PS50033", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50033" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "UBX", "eco_id": "ECO_0000259", "start_pos": 313, "end_pos": 390, "start_aa": "Ser", "end_aa": "Leu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0YLP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLP9" }, { "id": "PS50053", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50053" } ], 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{ "database": "Ensembl Peptide", "id": "ENSGALP00010017029.1", "url": "https://www.ensembl.org/id/ENSGALP00010017029.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:424018", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424018", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "hormone activity", "id": "GO:0005179", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005179", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLQ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLQ8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": 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}, { "id": "ENSGALG00000036598", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000036598", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100857276", "url": "https://www.ncbi.nlm.nih.gov/gene/100857276", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR026910", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026910", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR053891", "url": "https://www.ebi.ac.uk/interpro/entry/IPR053891", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:100857276", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100857276", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "ICRVYLA", "url": "https://omabrowser.org/oma/group/ICRVYLA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PB49", "url": "https://www.orthodb.org/?gene=A0A1D5PB49", "database": "OrthoDB", "categories": [ 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like 1 OS=Gallus gallus OX=9031 GN=KIAA1644 PE=4 SV=1 CANONICAL=A0A8V0YLW9-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PB49-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLW9/entry#A0A1D5PB49-1", "sequence": { "sequence": "MTSCGQQSLNVLMVLLSLLLSAVLSAHFRVCEPYTDYKGRYHFGFHCPRLSDNKSYIFCCHHNNTVFKYCCNETEFQTVMQMNLTGNADGYMHNNYSALLGVWIYGFFVVILLVLDLLYYSSMNYDICKFYLARWGIQGKWMTQGQSRWISSAQDPSQVQTQPQPETQPQTQPQPQPQTSQTVHTLKGDALSPPLMSFQSTSACMETI", "length": 208, "header": "tr|A0A1D5PB49-1|A0A1D5PB49_CHICK Computationally mapped isoform of Shisa like 1 OS=Gallus gallus OX=9031 GN=KIAA1644 PE=4 SV=2 CANONICAL=A0A8V0YLW9-1" }, "locus": { "chromosome": "1", "start_pos": 69400322, "end_pos": 69377096, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032117.1", "url": "https://www.ensembl.org/id/ENSGALT00010032117.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018907.1", "url": "https://www.ensembl.org/id/ENSGALP00010018907.1" } ] } }, { "isoform_ac": "A0A8V0YLW9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLW9/entry#A0A8V0YLW9-1", "sequence": { "sequence": "MEHLHFTAMLIKVLGQGEREVSTCSNKYMYLYSFGNHSIPQALQIPNDIVCEAIFSVVKVIMTVLSAHFRVCEPYTDYKGRYHFGFHCPRLSDNKSYIFCCHHNNTVFKYCCNETEFQTVMQMNLTGNADGYMHNNYSALLGVWIYGFFVVILLVLDLLYYSSMNYDICKFYLARWGIQGKWMTQGQSRWISSAQDPSQVQTQPQPETQPQTQPQPQPQTSQTVHTLKGDALSPPLMSFQSTSA", "length": 244, "header": "tr|A0A8V0YLW9-1|A0A8V0YLW9_CHICK Isoform 1 of Shisa like 1 OS=Gallus gallus OX=9031 GN=KIAA1644 PE=4 SV=1 CANONICAL=A0A8V0YLW9-1" }, "locus": { "chromosome": "1", "start_pos": 69392437, "end_pos": 69381709, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032115.1", "url": "https://www.ensembl.org/id/ENSGALT00010032115.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018905.1", "url": "https://www.ensembl.org/id/ENSGALP00010018905.1" } ] } }, { "isoform_ac": "A0A8V0YRU7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLW9/entry#A0A8V0YRU7-1", "sequence": { "sequence": "MTSCGQQSLNVLMVLLSLLLSAVLSAHFRVCEPYTDYKGRYHFGFHCPRLSDNKSYIFCCHHNNTVFKYCCNETEFQTVMQMNLTGNADGYMHNNYSALLGVWIYGFFVVILLVLDLLYYSSMNYDICKFYLARWGIQGKWMTQGQSRWISSAQDPSQVQTQPQPETQPQTQPQPQPQTSQTVHTLKGDALSPPLMSFQSTSA", "length": 203, "header": "tr|A0A8V0YRU7-1|A0A8V0YRU7_CHICK Computationally mapped isoform of Shisa like 1 OS=Gallus gallus OX=9031 GN=KIAA1644 PE=4 SV=1 CANONICAL=A0A8V0YLW9-1" }, "locus": { "chromosome": "1", "start_pos": 69400322, "end_pos": 69381709, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032119.1", "url": "https://www.ensembl.org/id/ENSGALT00010032119.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018909.1", "url": "https://www.ensembl.org/id/ENSGALP00010018909.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:100857276", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100857276", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZJY8-1", "protein_name": "Shisa N-terminal domain-containing protein", "gene_name": "Shisal1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MMTSCGQRSRNVLAVFSLLFPAVLSAHFRVCEPYTDHKGRYHFGFHCPRLSDNKTFVLCCHHNNTVFKYCCNETEFQAVMQANLTAGPEGYMHNNYTALLGVWIYGFFVLTLLVLDLLYYSAMNYDICKVYLTRWGIQGRWMKQDPRRWGNPARAPRPGQPAPQPQPPPGALPQAPQAVHTLRGDTHSPPLMAFQSSSA", "length": 199 }, "evidence": [ { "id": "A0A8V0YLW9", "url": "https://omabrowser.org/oma/group/A0A8V0YLW9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3MZN0-1", "protein_name": "Shisa like 1", "gene_name": "SHISAL1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MLVITASGNQCPGLGRSDLACGHTVGSARRIDASQTMTSCGQQPLNVLAVLSLLISAVLSAHFRVCEPYTDHKGRYHFGFHCPRLSDNKTFILCCHHNNTVFKYCCNETEFQAVMQANLTAGSEGYMHNNYTALLGVWIYGFFVLMLLVLDLLYYSAMNYDICKVYLARWGIHGRWMKQDPRRWGNPARAPRPGQPAPQPQPPPGPLPQAPQAVHTLQRDSHTPPLMTFQSSSA", "length": 234 }, "evidence": [ { "id": "A0A8V0YLW9", "url": "https://omabrowser.org/oma/group/A0A8V0YLW9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q0VBP7-1", "protein_name": "Protein shisa-like-1", "gene_name": "Shisal1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTSCGQRSRNVLAVFSLLFPAVLSAHFRVCEPYTDHKGRYHFGFHCPRLSDNKTFVLCCHHNNTVFKYCCNETEFQAVMQANLTAGPEGYMHNNYTALLGVWIYGFFVLTLLVLDLLYYSAMNYDICKVYLTRWGIQGRWMKQDPRRWGNPARAPRPGQPAPQPQPPPGTLPQAPQAVHTLRGDTHSPPLMTFQSSSA", "length": 198 }, "evidence": [ { "id": "A0A8V0YLW9", "url": "https://omabrowser.org/oma/group/A0A8V0YLW9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q1RMB5-1", "protein_name": "Protein shisa-like-1a", "gene_name": "shisal1a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MIMNGRWSFNTLAIIFILLSTAALSAHFRVCEPYSDHKGRYHFGFHCPRLSDNKTYIFCCHHNNTAFKYCCNETEFQSVMQLNLTANSDSFAHNNYTALIGVWIYGFFVMVLLALDFLYYSAMNYELCRVYLEKWGLGGRWLKQARSQWHSTVQEGELNTGPGLSQQQQLHLHHHHHHHHPRHSLRGDTQSPTLLSFQTSTAW", "length": 203 }, "evidence": [ { "id": "A0A8V0YLW9", "url": "https://omabrowser.org/oma/group/A0A8V0YLW9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q3SXP7-1", "protein_name": "Protein shisa-like-1", "gene_name": "SHISAL1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTSCGQQSLNVLAVLFSLLFSAVLSAHFRVCEPYTDHKGRYHFGFHCPRLSDNKTFILCCHHNNTVFKYCCNETEFQAVMQANLTASSEGYMHNNYTALLGVWIYGFFVLMLLVLDLLYYSAMNYDICKVYLARWGIQGRWMKQDPRRWGNPARAPRPGQRAPQPQPPPGPLPQAPQAVHTLRGDAHSPPLMTFQSSSA", "length": 199 }, "evidence": [ { "id": "A0A8V0YLW9", "url": "https://omabrowser.org/oma/group/A0A8V0YLW9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLW9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLW9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 104, "end_pos": 106, "annotation": "n_glycosylation_sequon" }, { "start_pos": 113, "end_pos": 115, "annotation": "n_glycosylation_sequon" }, { "start_pos": 124, "end_pos": 126, "annotation": "n_glycosylation_sequon" }, { "start_pos": 136, "end_pos": 138, "annotation": "n_glycosylation_sequon" }, { "start_pos": 36, "end_pos": 38, "annotation": "n_glycosylation_sequon" }, { "start_pos": 94, "end_pos": 96, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YLW9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLW9" }, { "id": "PF13908", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13908" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Shisa N-terminal", "eco_id": "ECO_0000259", "start_pos": 71, "end_pos": 118, "start_aa": "Val", "end_aa": "Gln", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 104, "end_pos": 106 }, { "start_pos": 113, "end_pos": 115 }, { "start_pos": 124, "end_pos": 126 }, { "start_pos": 136, "end_pos": 138 }, { "start_pos": 36, "end_pos": 38 }, { "start_pos": 94, "end_pos": 96 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YLY1-1", "uniprot_ac": "A0A8V0YLY1", "uniprot_id": "A0A8V0YLY1_CHICK", "mass": { "chemical_mass": 45812.0, "monoisotopic_mass": 45812.0 }, "refseq": { "ac": "XP_015132449", "name": "procollagen C-endopeptidase enhancer 2 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015132449" }, "gene_names": [ { "name": "PCOLCE2", "type": "recommended", "evidence": [ { "id": "A0A8V0YLY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLY1" } ] }, { "name": "PCOLCE2", "type": "synonym", "evidence": [ { "id": "XP_015132449", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015132449" } ] } ], "protein_names": [ { "name": "Procollagen C-endopeptidase enhancer 2", "type": "synonym", "evidence": [ { "id": "A0A8V0YLY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLY1/entry#names_and_taxonomy" } ] }, { "name": "procollagen C-endopeptidase enhancer 2 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015132449", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015132449" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052540.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015132449", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015132449" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLY1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLY1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PCOLCE2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLY1", "locus": { "chromosome": "9", "start_pos": 10224992, "end_pos": 10245942, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010015809", "url": "https://www.ensembl.org/id/ENSGALG00010015809" } ] } } ], "crossref": [ { "id": "A0A8V0YLY1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YLY1", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00041", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00041", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd03576", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03576", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "429124", "url": "https://www.ncbi.nlm.nih.gov/gene/429124", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000859", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000859", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001134", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001134", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018933", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018933", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035814", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035814", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035914", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035914", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:429124", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:429124", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DVYNGHV", "url": "https://omabrowser.org/oma/group/DVYNGHV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YLY1", "url": "https://www.orthodb.org/?gene=A0A8V0YLY1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YV70", "url": "https://www.orthodb.org/?gene=A0A8V0YV70", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z027", "url": "https://www.orthodb.org/?gene=A0A8V0Z027", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24251", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24251", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24251:SF31", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24251:SF31", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00431", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00431", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01759", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01759", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015132449", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015132449", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YLY1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLY1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLY1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLY1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YV70", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YV70", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YV70-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YV70-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z027", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z027", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z027-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z027-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPPAAPRPLPLLLPLLLLLPGARPAAQPPRPTFTCGGVVSGESGFIGSEGFPGVYPPNSKCTWKITVPEGKVVVLSFRYLDLESDNLCRYDFVDIYSGHANGQRIGRFCGTVKPGALVSSSNKMLVQMTSDANTAGNGFIAKFSAAEPHERGDQYCGGRLEKPSGSFQTPNWPERDYPAGVTCSWHIVAPKNQLIELKFEKFDVERDNYCRYDYVAVFNGGEINDAKRIGKYCGDSPPAPIVSEKNELFIQFLSDLSLTADGFIGHYKFRPKKLPTTTVPPTTTTVPATSIPKPTVALCQQKCKRSGTPESNYCSSNFVITGTVISTTTRAGSLHATISIINVYKEGNLAIQQAGKNMSAKIIVVCKQCPLLRRGLNYIIMGQVEEDGRGKIFPNSFVMSFKTKNQKILNSLKNKTCYN", "length": 419, "header": "tr|A0A8V0YLY1-1|A0A8V0YLY1_CHICK Isoform 1 of Procollagen C-endopeptidase enhancer 2 OS=Gallus gallus OX=9031 GN=PCOLCE2 PE=4 SV=1 CANONICAL=A0A8V0YLY1-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YLY1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLY1/entry#A0A8V0YLY1-1", "sequence": { "sequence": "MPPAAPRPLPLLLPLLLLLPGARPAAQPPRPTFTCGGVVSGESGFIGSEGFPGVYPPNSKCTWKITVPEGKVVVLSFRYLDLESDNLCRYDFVDIYSGHANGQRIGRFCGTVKPGALVSSSNKMLVQMTSDANTAGNGFIAKFSAAEPHERGDQYCGGRLEKPSGSFQTPNWPERDYPAGVTCSWHIVAPKNQLIELKFEKFDVERDNYCRYDYVAVFNGGEINDAKRIGKYCGDSPPAPIVSEKNELFIQFLSDLSLTADGFIGHYKFRPKKLPTTTVPPTTTTVPATSIPKPTVALCQQKCKRSGTPESNYCSSNFVITGTVISTTTRAGSLHATISIINVYKEGNLAIQQAGKNMSAKIIVVCKQCPLLRRGLNYIIMGQVEEDGRGKIFPNSFVMSFKTKNQKILNSLKNKTCYN", "length": 419, "header": "tr|A0A8V0YLY1-1|A0A8V0YLY1_CHICK Isoform 1 of Procollagen C-endopeptidase enhancer 2 OS=Gallus gallus OX=9031 GN=PCOLCE2 PE=4 SV=1 CANONICAL=A0A8V0YLY1-1" }, "locus": { "chromosome": "9", "start_pos": 10245846, "end_pos": 10226001, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010038070.1", "url": "https://www.ensembl.org/id/ENSGALT00010038070.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021969.1", "url": "https://www.ensembl.org/id/ENSGALP00010021969.1" } ] } }, { "isoform_ac": "A0A8V0YV70-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLY1/entry#A0A8V0YV70-1", "sequence": { "sequence": "MKSLSEVTENCKHSSFVLRPTFTCGGVVSGESGFIGSEGFPGVYPPNSKCTWKITVPEGKVVVLSFRYLDLESDNLCRYDFVDIYSGHANGQRIGRFCGTVKPGALVSSSNKMLVQMTSDANTAGNGFIAKFSAAEPHERGDQYCGGRLEKPSGSFQTPNWPERDYPAGVTCSWHIVAPKNQLIELKFEKFDVERDNYCRYDYVAVFNGGEINDAKRIGKYCGDSPPAPIVSEKNELFIQFLSDLSLTADGFIGHYKFRPKKLPTTTVPPTTTTVPATSIPKPTVALCQQKCKRSGTPESNYCSSNFVITGTVISTTTRAGSLHATISIINVYKEGNLAIQQAGKNMSAKIIVVCKQCPLLRRGLNYIIMGQVEEDGRGKIFPNSFVMSFKTKNQKILNSLKNKTCYN", "length": 408, "header": "tr|A0A8V0YV70-1|A0A8V0YV70_CHICK Computationally mapped isoform of Procollagen C-endopeptidase enhancer 2 OS=Gallus gallus OX=9031 GN=PCOLCE2 PE=4 SV=1 CANONICAL=A0A8V0YLY1-1" }, "locus": { "chromosome": "9", "start_pos": 10245235, "end_pos": 10226001, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010038068.1", "url": "https://www.ensembl.org/id/ENSGALT00010038068.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021967.1", "url": "https://www.ensembl.org/id/ENSGALP00010021967.1" } ] } }, { "isoform_ac": "A0A8V0Z027-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLY1/entry#A0A8V0Z027-1", "sequence": { "sequence": "MPPAAPRPLPLLLPLLLLLPGARPAAQPPRPTFTCGGVVSGESGFIGSEGFPGVYPPNSKCTWKITVPEGKVVVLSFRYLDLESDNLCRYDFVDIYSGHANGQRIGRFCGTVKPGALVSSSNKMLVQMTSDANTAGNGFIAKFSAAEPHERGDQYCGGRLEKPSGSFQTPNWPERDYPAGVTCSWHIVAPKNQLIELKFEKFDVERDNYCRYDYVAVFNGGEINDAKRIGKYCGDSPPAPIVSEKNELFIQFLSDLSLTADGFIGHYKFRPKKLPTTTVPPTTTTVPATSIPKPTVALCQQKCKRSGTPESNYCSSNFVITGTVISTTTRAGSLHATISIINVYKEGNLAIQQAGKNMSAKIIVVCKQCPLLRRVIQSGKTTS", "length": 383, "header": "tr|A0A8V0Z027-1|A0A8V0Z027_CHICK Computationally mapped isoform of Procollagen C-endopeptidase enhancer 2 OS=Gallus gallus OX=9031 GN=PCOLCE2 PE=4 SV=1 CANONICAL=A0A8V0YLY1-1" }, "locus": { "chromosome": "9", "start_pos": 10245846, "end_pos": 10227292, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010038066.1", "url": "https://www.ensembl.org/id/ENSGALT00010038066.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021965.1", "url": "https://www.ensembl.org/id/ENSGALP00010021965.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:429124", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:429124", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "F1SKE7-1", "protein_name": "Procollagen C-endopeptidase enhancer 2", "gene_name": "PCOLCE2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRGAGAWAPLCLLLAAAAQPSQPQPPERPVFTCGGILTGESGFIGSEGFPGVYPPNSKCTWKITVPEGKVVVLNFRFIDLESDNLCRYDFVDVYNGHANGQRIGRFCGTFRPGALVSSGNKMMVQMISDANTAGNGFMAMFTAAEPNERGDRYCGGRLERPSGSFKTPNWPDRDYPAGVACVWHIVAPKNQLIELEFEKFDVERDNYCRYDYVAVFNGGEINDAERIGKYCGDSPPAPIVSERNELLIQFLSDLSLTADGFIGHYKFRPKKLPTTIAPPVTTTYPVTTSVKPTVALCQQKCKRTGTPESNYCSSNFVLAGTVITTIPRGGSLHATISIINIYKEGNLAVQQAGKNMSAKVIVVCKQCPLLRRGLNYIIMGQVGEDGRGRIMPNSFIMMFKTKNQKLLNALKNKQC", "length": 415 }, "evidence": [ { "id": "A0A8V0YLY1", "url": "https://omabrowser.org/oma/group/A0A8V0YLY1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q8R4W6-1", "protein_name": "Procollagen C-endopeptidase enhancer 2", "gene_name": "Pcolce2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGGASACIPLCLLLATARMARPQTPERPVFTCGGILTGESGFIGSEGFPGMYPPNSKCTWKITVPEGKVVVLNFRFIDLENDNLCRYDFVDVYNGHANGQRIGRFCGTFRPGSLVASGNKMTVQMISDANTAGSGFMATYSAAAPDGKGDRYCGGRLEKPSGTFKTPNWPDRDYPVGVTCVWHIIAPKNQLIELKFEKFDVERDNYCRYDYVAVFNGGEVNDAKRIGKYCGDSPPVPIVSERNELLIQFLSDLSLTADGFIGHYKFRPKKFPTTTTTPVTTTLPVTTGLKPTVALCQQKCRRMGTLESNYCSSNFVLAGTVITTVTRGGSLHATVSIISIYREGNLAIQQAGKNMSVKLTVVCRQCPLLRRGLNYIIMGQVGEDGRGKIMPNSFVKMFKNKNQKPMNALKNKQC", "length": 414 }, "evidence": [ { "id": "A0A8V0YLY1", "url": "https://omabrowser.org/oma/group/A0A8V0YLY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9UKZ9-1", "protein_name": "Procollagen C-endopeptidase enhancer 2", "gene_name": "PCOLCE2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRGANAWAPLCLLLAAATQLSRQQSPERPVFTCGGILTGESGFIGSEGFPGVYPPNSKCTWKITVPEGKVVVLNFRFIDLESDNLCRYDFVDVYNGHANGQRIGRFCGTFRPGALVSSGNKMMVQMISDANTAGNGFMAMFSAAEPNERGDQYCGGLLDRPSGSFKTPNWPDRDYPAGVTCVWHIVAPKNQLIELKFEKFDVERDNYCRYDYVAVFNGGEVNDARRIGKYCGDSPPAPIVSERNELLIQFLSDLSLTADGFIGHYIFRPKKLPTTTEQPVTTTFPVTTGLKPTVALCQQKCRRTGTLEGNYCSSDFVLAGTVITTITRDGSLHATVSIINIYKEGNLAIQQAGKNMSARLTVVCKQCPLLRRGLNYIIMGQVGEDGRGKIMPNSFIMMFKTKNQKLLDALKNKQC", "length": 415 }, "evidence": [ { "id": "A0A8V0YLY1", "url": "https://omabrowser.org/oma/group/A0A8V0YLY1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLY1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLY1" } ], "pmid": "" }, { "name": "transport vesicle", "id": "GO:0030133", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030133", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLY1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLY1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "heparin binding", "id": "GO:0008201", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008201", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLY1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLY1" } ], "pmid": "" }, { "name": "peptidase activator activity", "id": "GO:0016504", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016504", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLY1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLY1" } ], "pmid": "" }, { "name": "collagen binding", "id": "GO:0005518", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005518", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLY1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLY1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 357, "end_pos": 359, "annotation": "n_glycosylation_sequon" }, { "start_pos": 414, "end_pos": 416, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YLY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLY1" }, { "id": "PS01180", "database": "PROSITE", "url": "https://prosite.expasy.org/PS01180" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CUB", "eco_id": "ECO_0000259", "start_pos": 35, "end_pos": 146, "start_aa": "Cys", "end_aa": "Ala", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0YLY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLY1" }, { "id": "PS50189", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50189" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "NTR", "eco_id": "ECO_0000259", "start_pos": 299, "end_pos": 417, "start_aa": "Cys", "end_aa": "Cys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 357, "end_pos": 359 }, { "start_pos": 414, "end_pos": 416 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YLY2-1", "uniprot_ac": "A0A8V0YLY2", "uniprot_id": "A0A8V0YLY2_CHICK", "mass": { "chemical_mass": 11722.0, "monoisotopic_mass": 11722.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Mitochondrial import inner membrane translocase subunit TIM14", "type": "recommended", "evidence": [ { "id": "A0A8V0YLY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLY2/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLY2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLY2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLY2", "locus": {} } ], "crossref": [ { "id": "A0A8V0YLY2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YLY2", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR036869", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036869", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR12763", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12763", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12763:SF56", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12763:SF56", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YLY2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLY2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLY2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLY2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MARDIEAVQLIIAAVGFASHYALRILPKLDFSSCYRGGFEHKMTKQEEALIVEVSPTASRIKIREAYRWIMILNHPDKGAKHLLKITLKNDLEIKSESKKWN", "length": 102, "header": "tr|A0A8V0YLY2-1|A0A8V0YLY2_CHICK Isoform 1 of Mitochondrial import inner membrane translocase subunit TIM14 OS=Gallus gallus OX=9031 GN= PE=3 SV=1 CANONICAL=A0A8V0YLY2-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YLY2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLY2/entry#A0A8V0YLY2-1", "sequence": { "sequence": "MARDIEAVQLIIAAVGFASHYALRILPKLDFSSCYRGGFEHKMTKQEEALIVEVSPTASRIKIREAYRWIMILNHPDKGAKHLLKITLKNDLEIKSESKKWN", "length": 102, "header": "tr|A0A8V0YLY2-1|A0A8V0YLY2_CHICK Isoform 1 of Mitochondrial import inner membrane translocase subunit TIM14 OS=Gallus gallus OX=9031 GN= PE=3 SV=1 CANONICAL=A0A8V0YLY2-1" }, "locus": { "chromosome": "3", "start_pos": 64232241, "end_pos": 64230608, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032132.1", "url": "https://www.ensembl.org/id/ENSGALT00010032132.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018922.1", "url": "https://www.ensembl.org/id/ENSGALP00010018922.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 57, "start_aa": "Thr", "end_pos": 57, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr57", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLY2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLY2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLY2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLY2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 57 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 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The reference sequence was derived from JAENSK010000025.1. 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"MTLMVFLLIFITETATEKLCPLRASIDVLEGEYFFLCFPKSKQQHSWKEEHTINWHKESAGRQKQIQETQRIVSQMNFLEFWPVELGDSGNYFVTQSNGSLTIQNWTLNVLERNKSSCFNQNHLTTEIQSAGIGHSLKCSDLSVNENDSITWYKDCKRYENERGRELDFKTLSVQHSGIYTCKISISREGKIYHSTNTIRLVVEEDAPETVTLEIVGRNEEIQTEIGKEETLNCTGFLGYYIQEDASLYWWFNDTFPKKCSGIPEADPPICEEDLKKSHLGNKFYITRLLRIKKVREEDLHHNFTCKLQADEITHIKVVKLKKGNTRDLSMHVFTTGMILAVLFPCVAMAVVVVCVIFRVDLVLFYRNISQRDDTAGDGKEYDAFVSYLKDCVSTSEEEREFALRILPMILEENFGYKLCIFERDVSPGGAVVDDIHSFIDKSRRLIIILSQNYISDRAIYELESGLHKALVERKMKIILIEYMPISDYDFLPESLSLLPSKRVVKWKKDKSLPVNSRFWKTLRYLMPAKPTKSNTKGHCMNLDLGSEGTQPWTGDCDFSTVI", "length": 563, "header": "tr|A0A8V0YLY8-1|A0A8V0YLY8_CHICK Isoform 1 of Interleukin 18 receptor 1 OS=Gallus gallus OX=9031 GN=IL18R1 PE=3 SV=1 CANONICAL=A0A8V0YLY8-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YLY8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLY8/entry#A0A8V0YLY8-1", "sequence": { "sequence": "MTLMVFLLIFITETATEKLCPLRASIDVLEGEYFFLCFPKSKQQHSWKEEHTINWHKESAGRQKQIQETQRIVSQMNFLEFWPVELGDSGNYFVTQSNGSLTIQNWTLNVLERNKSSCFNQNHLTTEIQSAGIGHSLKCSDLSVNENDSITWYKDCKRYENERGRELDFKTLSVQHSGIYTCKISISREGKIYHSTNTIRLVVEEDAPETVTLEIVGRNEEIQTEIGKEETLNCTGFLGYYIQEDASLYWWFNDTFPKKCSGIPEADPPICEEDLKKSHLGNKFYITRLLRIKKVREEDLHHNFTCKLQADEITHIKVVKLKKGNTRDLSMHVFTTGMILAVLFPCVAMAVVVVCVIFRVDLVLFYRNISQRDDTAGDGKEYDAFVSYLKDCVSTSEEEREFALRILPMILEENFGYKLCIFERDVSPGGAVVDDIHSFIDKSRRLIIILSQNYISDRAIYELESGLHKALVERKMKIILIEYMPISDYDFLPESLSLLPSKRVVKWKKDKSLPVNSRFWKTLRYLMPAKPTKSNTKGHCMNLDLGSEGTQPWTGDCDFSTVI", "length": 563, "header": "tr|A0A8V0YLY8-1|A0A8V0YLY8_CHICK Isoform 1 of Interleukin 18 receptor 1 OS=Gallus gallus OX=9031 GN=IL18R1 PE=3 SV=1 CANONICAL=A0A8V0YLY8-1" }, "locus": { "chromosome": "1", "start_pos": 134028742, "end_pos": 134013072, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033212.1", "url": "https://www.ensembl.org/id/ENSGALT00010033212.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019624.1", "url": "https://www.ensembl.org/id/ENSGALP00010019624.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6A1C2-1", "protein_name": "Interleukin-18 receptor 1", "gene_name": "Il18r1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MHHEELILILCVLVVKSAPKSCIRRSQIHVVEGEPFYLKPCDMSAPMHNNETATMRWFKGNASHGYRELNMRSSPRIAFHGHALEFWPVELEDKGTYFSQVGNDRQNWTLNVTKRNKHSCFSEKLVTNRDVEVKKSLWITCENPSYGELINHTLLYKNCKEISKTPMILKDAEFGDEGYYSCVFSVHHNGQQYNITKTVNITVIEGNSKITPAIFGSKSAKVGVELGEDVELNCSAVLNRNDLFYWSIRKEDSLDPNVHEDRNETTWTFEGKLHASKILRIQKVTEKYLNVLYNCTVANEEATDTKSFILVRKETPDIQGHVFMRGITMVVLTSVAAVCVVILCIIYKVDLVLFYRRVAERDETLTDGKTYDAFVSYLRECHPENGEEYTFAVETLPRVLEKQFGYKLCIFERDVVPGGAVVDEIHSLIEKSRRLIIVLSKSYMTNGSRLELESGLHQALVERKIKIILIEFTPASNITFLPPSLKLLKSYRVLRWKADKPLSSKSRFWKNLLYLMPAKAVKPWREESEARPVLSAP", "length": 537 }, "evidence": [ { "id": "A0A8V0YLY8", "url": "https://omabrowser.org/oma/group/A0A8V0YLY8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q13478-1", "protein_name": "Interleukin-18 receptor 1", "gene_name": "IL18R1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNCRELPLTLWVLISVSTAESCTSRPHITVVEGEPFYLKHCSCSLAHEIETTTKSWYKSSGSQEHVELNPRSSSRIALHDCVLEFWPVELNDTGSYFFQMKNYTQKWKLNVIRRNKHSCFTERQVTSKIVEVKKFFQITCENSYYQTLVNSTSLYKNCKKLLLENNKNPTIKKNAEFEDQGYYSCVHFLHHNGKLFNITKTFNITIVEDRSNIVPVLLGPKLNHVAVELGKNVRLNCSALLNEEDVIYWMFGEENGSDPNIHEEKEMRIMTPEGKWHASKVLRIENIGESNLNVLYNCTVASTGGTDTKSFILVRKADMADIPGHVFTRGMIIAVLILVAVVCLVTVCVIYRVDLVLFYRHLTRRDETLTDGKTYDAFVSYLKECRPENGEEHTFAVEILPRVLEKHFGYKLCIFERDVVPGGAVVDEIHSLIEKSRRLIIVLSKSYMSNEVRYELESGLHEALVERKIKIILIEFTPVTDFTFLPQSLKLLKSHRVLKWKADKSLSYNSRFWKNLLYLMPAKTVKPGRDEPEVLPVLSES", "length": 541 }, "evidence": [ { "id": "A0A8V0YLY8", "url": "https://omabrowser.org/oma/group/A0A8V0YLY8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q61098-1", "protein_name": "Interleukin-18 receptor 1", "gene_name": "Il18r1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MHHEELILTLCILIVKSASKSCIHRSQIHVVEGEPFYLKPCGISAPVHRNETATMRWFKGSASHEYRELNNRSSPRVTFHDHTLEFWPVEMEDEGTYISQVGNDRRNWTLNVTKRNKHSCFSDKLVTSRDVEVNKSLHITCKNPNYEELIQDTWLYKNCKEISKTPRILKDAEFGDEGYYSCVFSVHHNGTRYNITKTVNITVIEGRSKVTPAILGPKCEKVGVELGKDVELNCSASLNKDDLFYWSIRKEDSSDPNVQEDRKETTTWISEGKLHASKILRFQKITENYLNVLYNCTVANEEAIDTKSFVLVRKEIPDIPGHVFTGGVTVLVLASVAAVCIVILCVIYKVDLVLFYRRIAERDETLTDGKTYDAFVSYLKECHPENKEEYTFAVETLPRVLEKQFGYKLCIFERDVVPGGAVVEEIHSLIEKSRRLIIVLSQSYLTNGARRELESGLHEALVERKIKIILIEFTPASNITFLPPSLKLLKSYRVLKWRADSPSMNSRFWKNLVYLMPAKAVKPWREESEARSVLSAP", "length": 537 }, "evidence": [ { "id": "A0A8V0YLY8", "url": "https://omabrowser.org/oma/group/A0A8V0YLY8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "interleukin-18 receptor complex", "id": "GO:0045092", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045092", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLY8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLY8" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLY8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLY8" } ], "pmid": "" }, { "name": "cell surface", "id": "GO:0009986", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009986", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLY8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLY8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLY8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLY8" } ], "pmid": "" }, { "name": "interleukin-1 receptor activity", "id": "GO:0004908", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004908", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLY8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLY8" } ], "pmid": "" }, { "name": "interleukin-18 binding", "id": "GO:0042007", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042007", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLY8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLY8" } ], "pmid": "" }, { "name": "interleukin-18 receptor activity", "id": "GO:0042008", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042008", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLY8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLY8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "positive regulation of non-canonical NF-kappaB signal transduction", "id": "GO:1901224", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901224", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLY8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLY8" } ], "pmid": "" }, { "name": "adaptive immune response", "id": "GO:0002250", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002250", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLY8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLY8" } ], "pmid": "" }, { "name": "positive regulation of type II interferon production", "id": "GO:0032729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032729", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLY8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLY8" } ], "pmid": "" }, { "name": "interleukin-18-mediated signaling pathway", "id": "GO:0035655", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035655", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLY8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLY8" } ], "pmid": "" }, { "name": "positive regulation of T-helper 1 cell cytokine production", "id": "GO:2000556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000556", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLY8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLY8" } ], "pmid": "" }, { "name": "negative regulation of cold-induced thermogenesis", "id": "GO:0120163", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120163", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLY8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLY8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 105, "end_pos": 107, "annotation": "n_glycosylation_sequon" }, { "start_pos": 114, "end_pos": 116, "annotation": "n_glycosylation_sequon" }, { "start_pos": 147, "end_pos": 149, "annotation": "n_glycosylation_sequon" }, { "start_pos": 233, "end_pos": 235, "annotation": "n_glycosylation_sequon" }, { "start_pos": 253, "end_pos": 255, "annotation": "n_glycosylation_sequon" }, { "start_pos": 303, "end_pos": 305, "annotation": "n_glycosylation_sequon" }, { "start_pos": 368, "end_pos": 370, "annotation": "n_glycosylation_sequon" }, { "start_pos": 98, "end_pos": 100, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YLY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLY8" }, { "id": "PS50835", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50835" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ig-like", "eco_id": "ECO_0000259", "start_pos": 136, "end_pos": 193, "start_aa": "Ser", "end_aa": "Tyr", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0YLY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLY8" }, { "id": "PS50104", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50104" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "TIR", "eco_id": "ECO_0000259", "start_pos": 380, "end_pos": 527, "start_aa": "Lys", "end_aa": "Met", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 105, "end_pos": 107 }, { "start_pos": 114, "end_pos": 116 }, { "start_pos": 147, "end_pos": 149 }, { "start_pos": 233, "end_pos": 235 }, { "start_pos": 253, "end_pos": 255 }, { "start_pos": 303, "end_pos": 305 }, { "start_pos": 368, "end_pos": 370 }, { "start_pos": 98, "end_pos": 100 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YLZ0-1", "uniprot_ac": "A0A8V0YLZ0", "uniprot_id": "A0A8V0YLZ0_CHICK", "mass": { "chemical_mass": 48502.0, "monoisotopic_mass": 48502.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "RNase H type-1 domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A8V0YLZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLZ0/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLZ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLZ0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLZ0", "locus": {} } ], "crossref": [ { "id": "A0A8V0YLZ0", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YLZ0", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR001584", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001584", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002156", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002156", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012337", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012337", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036397", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036397", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PF00075", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00075", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YLZ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLZ0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLZ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLZ0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YU63", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YU63", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YU63-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YU63-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MFKGKVPSTHHATDATWSKWIALITQRARMGNLSRPGILEVIMDWPEGKKFGASPGEEVSRAKEAPPYNELSENEKKYALFTGGSCHIVGKYRRWKAAVWSPMRQVAEATEGKGESSQFAEVKAVQLALDVTEGEGWPVLYLYTDSWMVANALWGWLQQWEQNNWQRRGKPIWSAELWKDIAAQIKNVVVKARHIDAHVPKSQATEEQKNNHQVDQAARIEVAQIDLDWQNKGELFLARWAHETSGHQRRDATYKWARDREVDLAMDAITQVIHDCETCAIIKQAKRMKPLWEEGQWQKYKYGEAWQIDYITLPRSCNEKNYVSQRTSRSEKEDTSRKIRHLVACSLLHFCLLPGEEWVCFPSRAPSSSKVFGFGNSLTLSVSLSLSLSLSLFRSLSFHLIYYPYSQLDCIISCHLAFQHRS", "length": 422, "header": "tr|A0A8V0YLZ0-1|A0A8V0YLZ0_CHICK Isoform 1 of RNase H type-1 domain-containing protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0YLZ0-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YLZ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLZ0/entry#A0A8V0YLZ0-1", "sequence": { "sequence": "MFKGKVPSTHHATDATWSKWIALITQRARMGNLSRPGILEVIMDWPEGKKFGASPGEEVSRAKEAPPYNELSENEKKYALFTGGSCHIVGKYRRWKAAVWSPMRQVAEATEGKGESSQFAEVKAVQLALDVTEGEGWPVLYLYTDSWMVANALWGWLQQWEQNNWQRRGKPIWSAELWKDIAAQIKNVVVKARHIDAHVPKSQATEEQKNNHQVDQAARIEVAQIDLDWQNKGELFLARWAHETSGHQRRDATYKWARDREVDLAMDAITQVIHDCETCAIIKQAKRMKPLWEEGQWQKYKYGEAWQIDYITLPRSCNEKNYVSQRTSRSEKEDTSRKIRHLVACSLLHFCLLPGEEWVCFPSRAPSSSKVFGFGNSLTLSVSLSLSLSLSLFRSLSFHLIYYPYSQLDCIISCHLAFQHRS", "length": 422, "header": "tr|A0A8V0YLZ0-1|A0A8V0YLZ0_CHICK Isoform 1 of RNase H type-1 domain-containing protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0YLZ0-1" }, "locus": { "chromosome": "4", "start_pos": 18625733, "end_pos": 18623741, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033505.1", "url": "https://www.ensembl.org/id/ENSGALT00010033505.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019760.1", "url": "https://www.ensembl.org/id/ENSGALP00010019760.1" } ] } }, { "isoform_ac": "A0A8V0YU63-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLZ0/entry#A0A8V0YU63-1", "sequence": { "sequence": "MRKWHDQDTPVLRALVRELQNRPTTSVVPPVTTGGSCHIVGKYRRWKAAVWSPMRQVAEATEGKGESSQFAEVKAVQLALDVTEGEGWPVLYLYTDSWMVANALWGWLQQWEQNNWQRRGKPIWSAELWKDIAAQIKNVVVKARHIDAHVPKSQATEEQKNNHQVDQAARIEVAQIDLDWQNKGELFLARWAHETSGHQRRDATYKWARDREVDLAMDAITQVIHDCETCAIIKQAKRMKPLWEEGQWQKYKYGEAWQIDYITLPRSCNGKHYVLIMVEATTGWLETYAVPHATARNTILGLEKQVLW", "length": 308, "header": "tr|A0A8V0YU63-1|A0A8V0YU63_CHICK Computationally mapped isoform of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0YLZ0-1" }, "locus": { "chromosome": "4", "start_pos": 18624811, "end_pos": 18622024, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033509.1", "url": "https://www.ensembl.org/id/ENSGALT00010033509.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019762.1", "url": "https://www.ensembl.org/id/ENSGALP00010019762.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "nucleic acid binding", "id": "GO:0003676", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003676", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLZ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLZ0" } ], "pmid": "" }, { "name": "RNA-DNA hybrid ribonuclease activity", "id": "GO:0004523", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004523", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLZ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLZ0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "DNA integration", "id": "GO:0015074", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015074", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLZ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLZ0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 32, "end_pos": 34, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YLZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLZ0" }, { "id": "PS50879", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50879" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RNase H type-1", "eco_id": "ECO_0000259", "start_pos": 74, "end_pos": 223, "start_aa": "Asn", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 32, "end_pos": 34 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YM04-1", "uniprot_ac": "A0A8V0YM04", "uniprot_id": "A0A8V0YM04_CHICK", "mass": { "chemical_mass": 151608.0, "monoisotopic_mass": 151608.0 }, "refseq": { "ac": "XP_025010675", "name": "SH3 domain and tetratricopeptide repeat-containing protein 2 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025010675" }, "gene_names": [ { "name": "SH3TC2", "type": "recommended", "evidence": [ { "id": "A0A8V0YM04", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM04" } ] }, { "name": "SH3TC2", "type": "synonym", "evidence": [ { "id": "XP_025010675", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025010675" } ] } ], "protein_names": [ { "name": "SH3 domain and tetratricopeptide repeat-containing protein 2 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_025010675", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025010675" } ] }, { "name": "SH3 domain and tetratricopeptide repeats 2", "type": "synonym", "evidence": [ { "id": "A0A8V0YM04", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM04/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 1% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052544.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_025010675.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_025010675", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025010675" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YM04", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM04" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SH3TC2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM04", "locus": { "chromosome": "13", "start_pos": 8220629, "end_pos": 8206471, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012312", "url": "https://www.ensembl.org/id/ENSGALG00010012312" } ] } } ], "crossref": [ { "id": "426627", "url": "https://www.ncbi.nlm.nih.gov/gene/426627", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011990", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011990", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019734", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019734", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036028", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036028", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042772", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042772", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:426627", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:426627", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HLETMYL", "url": "https://omabrowser.org/oma/group/HLETMYL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YM04", "url": "https://www.orthodb.org/?gene=A0A8V0YM04", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22647", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22647", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22647:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22647:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07653", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07653", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_025010675", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025010675", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YM04", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM04", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YM04-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM04-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQERMEGAGGAAGGASSTAAACRLGAGGDAGHMGCCLGAPWHQDLALGCTAEECESCCPHSPLLLPRWDSLQHSTAERRGRWWWEKTMASGKAGASEPSSPAEAAEGSPDPSSVLLAAGEDFPPEISLFFSIESRSSRCRNAQLQEAARRKLWALESDDRDVCALFKELSARLLCIQAQEDRFLLTFKTLEEVWKFSTYLTLGYVGRCLEQLLFEQEYWLNCALVEDTEIRVSMDENRLATIYLGLLLQEGHFFSRAVPGVCQPGGEGQEGLQLCRNELVHVKNIGGESKWEGMSLLTGQRGLVPVTALEPVSHPFYQWFLKNYAMSFGISQEISGTTSQPIAKGKCTATADHRGAAWDELSFSKGDSIEVVGFFLPGLPWFVGRSLSSGNIGFVPVRFVNAEACEPLEKGLVFLSEEENLPFLRMPCNGGEQHFATLLGELARTDITSVYRLDGFEPTAMFPKAPSEAVARGCKDTQLLQSWEEINSLVTASTSEQSSPGSESAPATWEDVLLDKLNDFDDPKFFIDLNAGHMEDADVFEPILTFLNQDSYMPCFQSLYDLSFSFLNSTFYGFSDEDELVLYLETSRNWAKRTHSVWAHVRLCFLLGKLCMKKVKFSQARVYFEEAMSTLDRGLEDLPLLAALHVNLASIYLKQNMKNKFFSLLGKMVALLVCLPGRSFSSEHELRVMMYVLREAIVVGNAPLEARVCFLIVKLFLQLGKNDEVLPFIEHLQCLCTTSLSQDTSAVLLDATPILSYLYDKKYLPNIALASARSFVPSGIKGAATPIWKAGFILQNMSKLLGSQLERSSIPALACSYLKQALHFSCESRALTTQRSLCTVLSRMYLQHGVLDGAVCYAAQAVAFSRLIGEEEAFESSLSLGWMYLLSSQSGPAADIMGQLLHSLHGTDSVTQGGAVHNLLAIALKGAGQVQKAAENYLRALHKAKETGNKRNQAIALANLGQLSQSRGASQLSELYLLQAAQLYAELQGSEELELESVHVMLWLAQAMVSRQRMEDGKLCYELALVFALKWHNVRSQLHVTEALCHFYSQVCPSLQACITYHEHRVSLAQKLQDRELEGNVRQTLSQLYQALGTPEALRQSLDCTKQSLRIFIDLEETGKAAEAWLQAGRLYYLMQEDELVEMYFQAAIETALKAENFSLAMDLYEKAGDNFFNGTRHRDQAVEFYRGGAVPLARKLQAIQTELRLFNKLTELQMGLQGYEKALEFATLAARLSIRVGDQLQELVAFHRLATVYYFLQMYEMAEDCYLKTLALRPPMLQCSGEALYYCKVYCHLGNLTLHKLKDEQDAAAYFLLALAAATELGDAELQSLIGAKLANIPRAPRRPVDMPGCATYRARWLSEGGHVV", "length": 1366, "header": "tr|A0A8V0YM04-1|A0A8V0YM04_CHICK Isoform 1 of SH3 domain and tetratricopeptide repeats 2 OS=Gallus gallus OX=9031 GN=SH3TC2 PE=4 SV=1 CANONICAL=A0A8V0YM04-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YM04-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM04/entry#A0A8V0YM04-1", "sequence": { "sequence": "MQERMEGAGGAAGGASSTAAACRLGAGGDAGHMGCCLGAPWHQDLALGCTAEECESCCPHSPLLLPRWDSLQHSTAERRGRWWWEKTMASGKAGASEPSSPAEAAEGSPDPSSVLLAAGEDFPPEISLFFSIESRSSRCRNAQLQEAARRKLWALESDDRDVCALFKELSARLLCIQAQEDRFLLTFKTLEEVWKFSTYLTLGYVGRCLEQLLFEQEYWLNCALVEDTEIRVSMDENRLATIYLGLLLQEGHFFSRAVPGVCQPGGEGQEGLQLCRNELVHVKNIGGESKWEGMSLLTGQRGLVPVTALEPVSHPFYQWFLKNYAMSFGISQEISGTTSQPIAKGKCTATADHRGAAWDELSFSKGDSIEVVGFFLPGLPWFVGRSLSSGNIGFVPVRFVNAEACEPLEKGLVFLSEEENLPFLRMPCNGGEQHFATLLGELARTDITSVYRLDGFEPTAMFPKAPSEAVARGCKDTQLLQSWEEINSLVTASTSEQSSPGSESAPATWEDVLLDKLNDFDDPKFFIDLNAGHMEDADVFEPILTFLNQDSYMPCFQSLYDLSFSFLNSTFYGFSDEDELVLYLETSRNWAKRTHSVWAHVRLCFLLGKLCMKKVKFSQARVYFEEAMSTLDRGLEDLPLLAALHVNLASIYLKQNMKNKFFSLLGKMVALLVCLPGRSFSSEHELRVMMYVLREAIVVGNAPLEARVCFLIVKLFLQLGKNDEVLPFIEHLQCLCTTSLSQDTSAVLLDATPILSYLYDKKYLPNIALASARSFVPSGIKGAATPIWKAGFILQNMSKLLGSQLERSSIPALACSYLKQALHFSCESRALTTQRSLCTVLSRMYLQHGVLDGAVCYAAQAVAFSRLIGEEEAFESSLSLGWMYLLSSQSGPAADIMGQLLHSLHGTDSVTQGGAVHNLLAIALKGAGQVQKAAENYLRALHKAKETGNKRNQAIALANLGQLSQSRGASQLSELYLLQAAQLYAELQGSEELELESVHVMLWLAQAMVSRQRMEDGKLCYELALVFALKWHNVRSQLHVTEALCHFYSQVCPSLQACITYHEHRVSLAQKLQDRELEGNVRQTLSQLYQALGTPEALRQSLDCTKQSLRIFIDLEETGKAAEAWLQAGRLYYLMQEDELVEMYFQAAIETALKAENFSLAMDLYEKAGDNFFNGTRHRDQAVEFYRGGAVPLARKLQAIQTELRLFNKLTELQMGLQGYEKALEFATLAARLSIRVGDQLQELVAFHRLATVYYFLQMYEMAEDCYLKTLALRPPMLQCSGEALYYCKVYCHLGNLTLHKLKDEQDAAAYFLLALAAATELGDAELQSLIGAKLANIPRAPRRPVDMPGCATYRARWLSEGGHVV", "length": 1366, "header": "tr|A0A8V0YM04-1|A0A8V0YM04_CHICK Isoform 1 of SH3 domain and tetratricopeptide repeats 2 OS=Gallus gallus OX=9031 GN=SH3TC2 PE=4 SV=1 CANONICAL=A0A8V0YM04-1" }, "locus": { "chromosome": "13", "start_pos": 8220315, "end_pos": 8206782, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029475.1", "url": "https://www.ensembl.org/id/ENSGALT00010029475.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017132.1", "url": "https://www.ensembl.org/id/ENSGALP00010017132.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:426627", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:426627", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0AB32T7U2-1", "protein_name": "SH3 domain and tetratricopeptide repeat-containing protein 2 isoform X1", "gene_name": "sh3tc2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MACCCCCCCPVPCLRNCFLFSAISPAELDALWNDPPYTLAAVSELFPPNDAMTADEEAEAEAEAEVEAEGISREIYWRRKETFSGSSTVSSSGERLSPDVVLLFSGRWRSSVAPDDQLQEALRTRLRVVESNSQDVVQLFKDLSARLLSVHAEKDSFVITFKTVEEIWKFSTYLALGYVARCLENFLCDQSFWLDPALLSDVEISVTVDEDHLATLYLGLLLQEGTFFGKTLYKSDCKEEEEELNYRRNDLVMVKDIGQEAIWEGTLLSTGKHGLVPVHDMQPLPYPFYQWFLKKYPGNAGGISVTEGLFDHPVVVGTCVAVVDHYPVVKDELHLRIGDQIKIEGFLFNTLSMFIGRHLTSGETGFVHKAHVKPESTERLNGQLVFLSEEERTALSKLNPCLEPSQADVLTNLFSTDISTVYRLDRLDDSDFTYIRNHPIPEQKTTVDQRKRTVSEKSDATPYHSSPRQSFSASRNHLDRDSEVLSFNLEDTFREMDEYEEDPPNFMDEGIWETEEAERCDPILTLLNLEYFQDTFRTLYDLSYSFLDTFFNGLPEDEVLQHLENLREGAKKGRMLWAHRRACFLLGRLCAKKLKYSQARVYFEEASKVPVNGFNDKPLLIALYTNLTSVYLKQKMMDKLPFTLEKASALILCLPCHNFCSVDEFELLQPIMRRAIIEKDKYLEARTCYLSVCLFLHLRKIEEALPFVERLQFLIITLSVEEGRQIAPVDLNWLLCRLYHKKYLPFLALASLSLDSGQDHSLNDAFQKIELFIKNSVRLNPHWKENISVLPAQVVVYLQQALAIASQGEDLKTQRDLCLSLASVYQQHGALKKAVPYAQHAAKTGNQINEEEGFEASILLAWLLVMTDEPIQAQNNLRPLLKSLNETDSPTQRGVVYNLLALCLRKQARVQEAARNFYCALQISRENGNKRNEALALANLGCLSLSIGASGLAECFLLKSFHLFQFLSESPTDQEHVQVLLWLGRSYKDRGGSQEVRLWFEMGLLIAISANNLHSQMVVAKVLSRHYADLLLYGQCIVYYEHCVSLCRRLKNKQLEGEYLELLSSLYLSLNTEKSSRKSLDCSKQSLRISIDLGKRQEESETWLQVGRIYYLINEDELADMYLQAAVKTALRMNDPCFAMSIYEEAGDVFFKGHRNQIAALPFYRDGSLPFARSIKDVHSEFRLLSKLTELLMKQKQYEEALQYATLAVQVSATTGVLLNERASFHRLASVYFSLGKYEMAENYYLKSLSLCPTALEHAIEVRYYVKVYCRLADLTLYRLKDAFDAMGYFHLALAAALEDKESLSTLYIIYMKLAEIHANYMPDAELSKSYMDRAQSLRNELAGYTDSKDTEETDEADADIDNKSAHSDASSGTSTLTESSMINTSLTINAQKEPEHSNGSHKDDTNTNRSDETDSGPADHTNPETSCEDNANHSNGSTLKEGLTFVI", "length": 1448 }, "evidence": [ { "id": "A0A8V0YM04", "url": "https://omabrowser.org/oma/group/A0A8V0YM04/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1M9P6-1", "protein_name": "SH3 domain and tetratricopeptide repeats 2", "gene_name": "Sh3tc2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGGSQGSPDWRSQGPWPREDGAHMGGCFCIPGERSLPWGPGKEGSSKDPPGLTEDISSLENKRKCFLPQNMTQDLVLSFWVRSRSRRCVNAALQEAARRRLWALENEAHEVHALFKDLSARLVSVQSQKDQFLITFKTLEEIWKFSTYLNLGYVSTCLEHLFFDHTYWLNSRLVDDTEIQVSVDDTHLENIYLGLLLQEGHFFCRAMCSVTQPADKEGEYLTLCKNELISVLSGGESDWEGMSLVTGQRGLVPVSALEPLPVSFHQWFLKNHPGICGLPRKKDWTGSCQIGRGRCKALMDYQQEERDELGFLQGESIDVIGFVIPGLRWFIGKSMSSGKVGFVPTRSIDLDSCSPVSKNSVFFSDEERCSLWSPGGDRKAECSGFLSALAHTDITSVYRLSEFESIQNLQNDLSASQPEGFREARSGGTWMERKTMGSRRSSSSLDSSLEDELISASSDSYHLPEPDDLDDPELFMDLSTSLEEDEMEHFAPILAFLDHEGYTDHFKSLYDFSFSFLTSSFYSFSEEDELVAYLETSRKWAKMTHRTWAHARLCFLLGRLSIRKTKLSQARVYFEEAIRVLDGAFEDLSLVAALYINLAAIYLRQRLRHKGPILLEKAGALLACLPDREFSAKNELDVVTYVLRQGIVAGSGPLEARSCFLAIRLLLNLGRHEEVLPFAERLQLLSGHSPASEVTATMLSSLYDKKYLPHLAVASVQKRGPQSARGMSVAIWQAYLVLQNATKILGVPFSSWCEVSALACPTLRQALAACEEQTDLNIQRTLCLLLSKMYLQHRSPDGSVQYLSQAHVLGKLLGEEEAFESSLCLAWAYLLARQTKKALEILEPLLCSLRETECVTQRGVVHNLLGLAFQDEGRTSRAAKSYLRALIRAREMGNIRNQAVSMANLGHLTLKSCMQQSARGYLLQAVRLYSEIQASKETDMELVQVLLWLGQALVSGHQLVHSRLCYEMALLFGLRHRHLNSQLQVTKSLCHFYSSVSPNPDACITYHEHWLALAQQLRDREMEGRLLESLGQLYRNLNTSRSLRRSLACIKESLRIFVDLGERDKAAEAWLGAGRLHYLMQEDELVEVYLQEAIQTALRSEELSLALKLYEEAGDVFFNGTRHRHRAVEYYRAGAVPLARRMKALRTELRIFNKLTELQISLRGYEKALEFATLAARLSVLTGDQKQELVAFHRLATVYFSLNMYEMAEDCYLKTLSLCPPWLQSPKEALYYAKVYCRLGRLTFYQLKDAHDATEYFLLALAAAVLVGDEELQDTIKNRLDSICQSPLWHSKPLGCSSERSRWLSGGSLAL", "length": 1311 }, "evidence": [ { "id": "A0A8V0YM04", "url": "https://omabrowser.org/oma/group/A0A8V0YM04/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q80VA5-1", "protein_name": "SH3 domain and tetratricopeptide repeat-containing protein 2", "gene_name": "Sh3tc2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGGCFCIPGERSLPWGPGKEGSSKDPPGLAEDTSSLENKRKCFLPQNMTQDLVLSFCVKSRSRRCVNAALQEAARRRLWALENEAQEVHALFKDLSARLVSVQSQKDQFLITFKTLEEIWKFSTYLNLGYVSICLEHLFFDHTYWLNSRLVDDTEIQVSVDDNHLENIYLGLLLQEGHFFCRAVCSVAQPADKEGEYLTLCKNELISVLSGGESECEAMSLVTGQRGLVPMSALEPLPVPFHQWFLKNHPGICGLPRKRDWTGSGQIGRGRCKALMDYEQEERDELCFLQGESIDVIGFVIPGLQWFIGKSVSSGEVGFVPTRSIDLDSCSPMSKNSAFFSDEERSSLWSPGSERKAECSGFLCSLAHTDITSIYRLSEFEAIQNLQNDLSASQPEGFREARSGGTWMERQTIGSRRSSGSGDSSPEEDELISASSDSYHLPEPEDLDDPELFMDLSTSLEEDDVEHFAPILAFLDHEGYTDHFKSLYDFSFSFLTSSFYSFSEEDELVAYLETSRKWAKMSHMTWAHARLCFLLGRLSIRKTKLSQARVYFEEAIRVLDGAFEDLSLVAALYINLAAIYLRQRLRHKGPTLLEKAGALLACLPDHEFSTKNELDVVTYVLRQGIVVGSGLLEARSCFLAIRLLLSLGRHEEVVPFAERLQLLSGHPPASEATATMLSSLYDKKYLPHLAVASVQKRGPQSARGMSLSIWQAYLVLQNATKILGVPSSNWCEVSALACPTLRQALAACEELSDQDIQRTLCLILSKMYLQHQSPDGSVHYLSQAHVLGKLLGEEEAFESSLCLAWAYLLGRQTEKALEILEPLLCSLRETECVTQRGVVHNLLGLAFEDEGRTSRAAKSYLRALIRAREMGNIRNQAVSMANLGHLTLKSCMQQSARGYLLQAVRLYSELQASKETDMELVQVLLWLGQASVSGHQLVHSRLCYEMALLFGLRHQHLSSQLQVTKSLCHFYSSVSPNPDACITYHEHWLALAQQLRDREMEGQLLESLGQLYRNLNTSRSLRRSLACIKESLRIFVDLGERDKAAEAWLGAGRLHYLMQEDELVELYLQEAIQTALRSEEPSLALKLYEEAGDVFFNGTRHRHRAVEYYRAGAVPLARRMKALRTELRIFNKLTELQISLEGYEKALEFATLAARLSVLTGDQKQELVAFHRLATVYFSLNMYEMAEDCYLKTLSLCPPWLQSPKEALYYAKVYCRLGRLTFYQLKDAHDATEYFLLALAAAVLMGDEELQNTIKNRLDSICQSPLWHSNPFGCSSERARWLSGGSLAL", "length": 1289 }, "evidence": [ { "id": "A0A8V0YM04", "url": "https://omabrowser.org/oma/group/A0A8V0YM04/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8TF17-1", "protein_name": "SH3 domain and tetratricopeptide repeat-containing protein 2", "gene_name": "SH3TC2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGGCFCIPRERSLTRGPGKETPSKDPTVSSECIASSEYKEKCFLPQNINPDLTLSFCVKSRSRRCVNGPLQEAARRRLWALENEDQEVRMLFKDLSARLVSIQSQRAQFLITFKTMEEIWKFSTYLNLGYVSMCLEHLLFDHKYWLNCILVEDTEIQVSVDDKHLETIYLGLLIQEGHFFCRALCSVTPPAEKEGECLTLCKNELISVKMAEAGSELEGVSLVTGQRGLVLVSALEPLPLPFHQWFLKNYPGSCGLSRKRDWTGSYQIGRGRCKALTGYEPGEKDELNFYQGESIEIIGFVIPGLQWFIGKSTSSGQVGFVPTRNIDPDSYSPMSRNSAFLSDEERCSLLALGSDKQTECSSFLHTLARTDITSVYRLSGFESIQNPPNDLSASQPEGFKEVRPGRAWEEHQAVGSRQSSSSEDSSLEEELLSATSDSYRLPEPDDLDDPELLMDLSTGQEEEAENFAPILAFLDHEGYADHFKSLYDFSFSFLTSSFYSFSEEDEFVAYLEASRKWAKKSHMTWAHARLCFLLGRLSIRKVKLSQARVYFEEAIHILNGAFEDLSLVATLYINLAAIYLKQRLRHKGSALLEKAGALLACLPDRESSAKHELDVVAYVLRQGIVVGSSPLEARACFLAIRLLLSLGRHEEVLPFAERLQLLSGHPPASEAVASVLSFLYDKKYLPHLAVASVQQHGIQSAQGMSLPIWQVHLVLQNTTKLLGFPSPGWGEVSALACPMLRQALAACEELADRSTQRALCLILSKVYLEHRSPDGAIHYLSQALVLGQLLGEQESFESSLCLAWAYLLASQAKKALDVLEPLLCSLKETESLTQRGVIYNLLGLALQGEGRVNRAAKSYLRALNRAQEVGDVHNQAVAMANLGHLSLKSWAQHPARNYLLQAVRLYCELQASKETDMELVQVFLWLAQVLVSGHQLTHGLLCYEMALLFGLRHRHLKSQLQATKSLCHFYSSVSPNPEACITYHEHWLALAQQLRDREMEGRLLESLGQLYRNLNTARSLRRSLTCIKESLRIFIDLGETDKAAEAWLGAGRLHYLMQEDELVELCLQAAIQTALKSEEPLLALKLYEEAGDVFFNGTRHRHHAVEYYRAGAVPLARRLKAVRTELRIFNKLTELQISLEGYEKALEFATLAARLSTVTGDQRQELVAFHRLATVYYSLHMYEMAEDCYLKTLSLCPPWLQSPKEALYYAKVYYRLGRLTFCQLKDAHDATEYFLLALAAAVLLGDEELQDTIRSRLDNICQSPLWHSRPSGCSSERARWLSGGGLAL", "length": 1288 }, "evidence": [ { "id": "A0A8V0YM04", "url": "https://omabrowser.org/oma/group/A0A8V0YM04/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YM04", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM04" } ], "pmid": "" }, { "name": "recycling endosome", "id": "GO:0055037", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055037", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YM04", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM04" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "regulation of intracellular protein transport", "id": "GO:0033157", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033157", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YM04", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM04" } ], "pmid": "" }, { "name": "regulation of ERBB signaling pathway", "id": "GO:1901184", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901184", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YM04", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM04" } ], "pmid": "" }, { "name": "regulation of endocytic recycling", "id": "GO:2001135", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2001135", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YM04", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM04" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1157, "end_pos": 1159, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1174, "end_pos": 1176, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1296, "end_pos": 1298, "annotation": "n_glycosylation_sequon" }, { "start_pos": 568, "end_pos": 570, "annotation": "n_glycosylation_sequon" }, { "start_pos": 796, "end_pos": 798, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YM04", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM04" }, { "id": "PS50002", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50002" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SH3", "eco_id": "ECO_0000259", "start_pos": 250, "end_pos": 314, "start_aa": "Glu", "end_aa": "His", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1157, "end_pos": 1159 }, { "start_pos": 1174, "end_pos": 1176 }, { "start_pos": 1296, "end_pos": 1298 }, { "start_pos": 568, "end_pos": 570 }, { "start_pos": 796, "end_pos": 798 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YM11-1", "uniprot_ac": "A0A8V0YM11", "uniprot_id": "A0A8V0YM11_CHICK", "mass": { "chemical_mass": 25775.0, "monoisotopic_mass": 25775.0 }, "refseq": {}, "gene_names": [ { "name": "SFN", "type": "recommended", "evidence": [ { "id": "A0A8V0YM11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM11" } ] } ], "protein_names": [ { "name": "Stratifin", "type": "synonym", "evidence": [ { "id": "A0A8V0YM11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM11/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YM11", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM11" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SFN", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM11", "locus": { "chromosome": "23", "start_pos": 2168500, "end_pos": 2166991, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010014011", "url": "https://www.ensembl.org/id/ENSGALG00010014011" } ] } } ], "crossref": [ { "id": "A0A8V0YM11", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YM11", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR000308", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000308", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023409", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023409", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023410", "url": 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4", "type": "synonym", "evidence": [ { "id": "A0A8V0YM52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM52/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YM52", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM52" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SLC38A4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM52", "locus": { "chromosome": "1", "start_pos": 31242303, "end_pos": 31274484, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010014033", "url": "https://www.ensembl.org/id/ENSGALG00010014033" } ] } } ], "crossref": [ { "id": "A0A8V0YM52", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YM52", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000009730", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000009730", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "417809", "url": "https://www.ncbi.nlm.nih.gov/gene/417809", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013057", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013057", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:417809", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417809", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QFANDDA", "url": "https://omabrowser.org/oma/group/QFANDDA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YM52", "url": "https://www.orthodb.org/?gene=A0A8V0YM52", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YMH9", "url": "https://www.orthodb.org/?gene=A0A8V0YMH9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YPB2", "url": "https://www.orthodb.org/?gene=A0A8V0YPB2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YUB4", "url": "https://www.orthodb.org/?gene=A0A8V0YUB4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1C7L9", "url": "https://www.orthodb.org/?gene=E1C7L9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22950", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22950", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22950:SF222", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22950:SF222", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01490", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01490", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-352230", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-352230", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YM52", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM52", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YM52-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM52-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YMH9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMH9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YMH9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMH9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YPB2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPB2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YPB2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPB2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YUB4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUB4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YUB4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUB4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C7L9", "url": "https://www.uniprot.org/uniprotkb/E1C7L9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C7L9-1", "url": "https://www.uniprot.org/uniprotkb/E1C7L9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLESADHSVDLMEQQKVNIELEEQSNSGESLEDNYTELIDSEKAAIRSPFASDDAESQKFLTNGYLDKKKLEDYNEEYHRGRASFGMSSFNLSNAIMGSGILGLSYAMANTGIILFVVLLLSVAVLSLYSVHLLLKTSKEGGSLIYEKLGEKAFGWPGKCSVFISVTMQNIGAMSSYLFIIKYELPEVIRAFMKLEENSGEWYLNGNYLVILVTVVIILPLSLLKTLGYLGYTSGFSLTCMVFFVSVVIFKKFQIPCPLPIMDHGVGNWTATNITLPMHLVMLPNESLSSGVNFMMDNTVGHVPGLEEPRDTFLKSGVEYEAHSDSSDTCQPKYFVFNSRTAYAIPILAFAFVCHPEVLPIYSELKDRSRKRMQNVSNISITGMLIMYLLAGLFGYLTFYGEVEDELLHTYTRVYTFDALLLSVRLAVLVAVTLTVPLVLFPIRSSISALLFPKRPFSWIRHLLIAAVILAFNSMLVIFVPTIKDIFGFIGASSATMLIFILPSAFYLRLVKKEPMRSPQKIGALIFLIVGIIFMIGIKKVTSPHGLVYQKGDSFGKPVDKAEHQICCPCLSPSTCDGCRME", "length": 582, "header": "tr|A0A8V0YM52-1|A0A8V0YM52_CHICK Isoform 1 of Solute carrier family 38 member 4 OS=Gallus gallus OX=9031 GN=SLC38A4 PE=1 SV=1 CANONICAL=A0A8V0YM52-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YM52-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM52/entry#A0A8V0YM52-1", "sequence": { "sequence": "MLESADHSVDLMEQQKVNIELEEQSNSGESLEDNYTELIDSEKAAIRSPFASDDAESQKFLTNGYLDKKKLEDYNEEYHRGRASFGMSSFNLSNAIMGSGILGLSYAMANTGIILFVVLLLSVAVLSLYSVHLLLKTSKEGGSLIYEKLGEKAFGWPGKCSVFISVTMQNIGAMSSYLFIIKYELPEVIRAFMKLEENSGEWYLNGNYLVILVTVVIILPLSLLKTLGYLGYTSGFSLTCMVFFVSVVIFKKFQIPCPLPIMDHGVGNWTATNITLPMHLVMLPNESLSSGVNFMMDNTVGHVPGLEEPRDTFLKSGVEYEAHSDSSDTCQPKYFVFNSRTAYAIPILAFAFVCHPEVLPIYSELKDRSRKRMQNVSNISITGMLIMYLLAGLFGYLTFYGEVEDELLHTYTRVYTFDALLLSVRLAVLVAVTLTVPLVLFPIRSSISALLFPKRPFSWIRHLLIAAVILAFNSMLVIFVPTIKDIFGFIGASSATMLIFILPSAFYLRLVKKEPMRSPQKIGALIFLIVGIIFMIGIKKVTSPHGLVYQKGDSFGKPVDKAEHQICCPCLSPSTCDGCRME", "length": 582, "header": "tr|A0A8V0YM52-1|A0A8V0YM52_CHICK Isoform 1 of Solute carrier family 38 member 4 OS=Gallus gallus OX=9031 GN=SLC38A4 PE=1 SV=1 CANONICAL=A0A8V0YM52-1" }, "locus": { "chromosome": "1", "start_pos": 31259937, "end_pos": 31244165, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033676.1", "url": "https://www.ensembl.org/id/ENSGALT00010033676.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019831.1", "url": "https://www.ensembl.org/id/ENSGALP00010019831.1" } ] } }, { "isoform_ac": "A0A8V0YMH9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM52/entry#A0A8V0YMH9-1", "sequence": { "sequence": "MLESADHSVDLMEQQKVNIELEEQSNSGESLEDNYTELIDSEKAAIRSPFASDDAESQKFLTNGYLDKKKLEDYNEEYHRGRASFGMSSFNLSNAIMGSGILGLSYAMANTGIILFVVLLLSVAVLSLYSVHLLLKTSKEGGSLIYEKLGEKAFGWPGKCSVFISVTMQNIGAMSSYLFIIKYELPEVIRAFMKLEENSGEWYLNGNYLVILVTVVIILPLSLLKTLGYLQEISNTLSSPHHGSWGWKLDSHQHHTANAPGHVTK", "length": 265, "header": "tr|A0A8V0YMH9-1|A0A8V0YMH9_CHICK Computationally mapped isoform of Solute carrier family 38 member 4 OS=Gallus gallus OX=9031 GN=SLC38A4 PE=1 SV=1 CANONICAL=A0A8V0YM52-1" }, "locus": { "chromosome": "1", "start_pos": 31259937, "end_pos": 31252436, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033665.1", "url": "https://www.ensembl.org/id/ENSGALT00010033665.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019824.1", "url": "https://www.ensembl.org/id/ENSGALP00010019824.1" } ] } }, { "isoform_ac": "A0A8V0YPB2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM52/entry#A0A8V0YPB2-1", "sequence": { "sequence": "MLESADHSVDLMEQQKVNIELEEQSNSGESLEDNYTELIDSEKAAIRSPFASDDAESQKFLTNGYLDKKKLEDYNEEYHRGRASFGMSSFNLSNAIMGSGILGLSYAMANTGIILFVVLLLSVAVLSLYSVHLLLKTSKEGGSLIYEKLGEKAFGWPGKCSVFISVTMQNIGAMSSYLFIIKYELPEVIRAFMKLEENSGEWYLNGNYLVILVTVVIILPLSLLKTLGYLGYTSGFSLTCMVFFVSVVIFKKFQIPCPLPIMDHGVGNWTATNITLPMHLVMLPNESLSSGVNFMMDNTVGHVPGLEEPRDTFLKSGVEYEAHSDSSDTCQPKYFVFNSRTAYAIPILAFAFVCHPEVLPIYSELKDRSRKRMQNVSNISITGMLIMYLLAGLFGYLTFYGEVEDELLHTYTRVYTFDALLLSVRLAVLVAVTLTVPLVLFPIRSSISALLFPKRPFSWIRHLLIAAVILAFNSMLVIFVPTIKDIFGFIGASSATMLIFILPSAFYLRLVKKEPMRSPQKIGLA", "length": 525, "header": "tr|A0A8V0YPB2-1|A0A8V0YPB2_CHICK Computationally mapped isoform of Solute carrier family 38 member 4 OS=Gallus gallus OX=9031 GN=SLC38A4 PE=1 SV=1 CANONICAL=A0A8V0YM52-1" }, "locus": { "chromosome": "1", "start_pos": 31259937, "end_pos": 31244826, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033685.1", "url": "https://www.ensembl.org/id/ENSGALT00010033685.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019835.1", "url": "https://www.ensembl.org/id/ENSGALP00010019835.1" } ] } }, { "isoform_ac": "A0A8V0YUB4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM52/entry#A0A8V0YUB4-1", "sequence": { "sequence": "MLESADHSVDLMEQQKVNIELEEQSNSGESLEDNYTELIDSEKAAIRSPFASDDAESQKFLTNGYLDKKKLEDYNEEYHRGRASFGMSSFNLSNAIMGSGILGLSYAMANTGIILFVVLLLSVAVLSLYSVHLLLKTSKEGGSLIYEKLGEKAFGWPGKCSVFISVTMQNIGAMSSYLFIIKYELPEVIRAFMKLEENSGEWYLNGNYLVILVTVVIILPLSLLKTLGYLGYTSGFSLTCMVFFVSVVIFKKFQIPCPLPIMDHGVGNWTATNITLPMHLVMLPNESLSSGVNFMMDNTVGHVPGLEEPRDTFLKSGVEYEAHSDSSDTCQPKYFVFNSRTAYAIPILAFAFVCHPEVLPIYSELKDRSRKRMQNVSNISITGMLIMYLLAGLFGYLTFYGEVEDELLHTYTRVYTFDALLLSVRLAVLVAVTLTVPLVLFPIRSSISALLFPKRPFSWIRHLLIAAVILAFNSMLVIFVPTIKDIFGFIGASSATMLIFILPSAFYLRLVKKEPMRSPQKIG", "length": 523, "header": "tr|A0A8V0YUB4-1|A0A8V0YUB4_CHICK Computationally mapped isoform of Solute carrier family 38 member 4 OS=Gallus gallus OX=9031 GN=SLC38A4 PE=1 SV=1 CANONICAL=A0A8V0YM52-1" }, "locus": { "chromosome": "1", "start_pos": 31259937, "end_pos": 31246310, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033671.1", "url": "https://www.ensembl.org/id/ENSGALT00010033671.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019828.1", "url": "https://www.ensembl.org/id/ENSGALP00010019828.1" } ] } }, { "isoform_ac": "E1C7L9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM52/entry#E1C7L9-1", "sequence": { "sequence": "MLESADHSVDLMEQQKVNIELEEQSNSGESLEDNYTELIDSEKAAIRSPFASDDAESQKFLTNGYLDKKKLEDYNEEYHRGRASFGMSSFNLSNAIMGSGILGLSYAMANTGIILFVVLLLSVAVLSLYSVHLLLKTSKEGGSLIYEKLGEKAFGWPGKCSVFISVTMQNIGAMSSYLFIIKYELPEVIRAFMKLEENSGEWYLNGNYLVILVTVVIILPLSLLKTLGYLGYTSGFSLTCMVFFVSVVIFKKFQIPCPLPIMDHGVGNWTATNITLPMHLVMLPNESLSSGVNFMMDNTVGHVPGLEEPRDTFLKSGVEYEAHSDSSDTCQPKYFVFNSRTAYAIPILAFAFVCHPEVLPIYSELKDRSRKRMQNVSNISITGMLIMYLLAGLFGYLTFYGEVEDELLHTYTRVYTFDALLLSVRLAVLVAVTLTVPLVLFPIRSSISALLFPKRPFSWIRHLLIAAVILAFNSMLVIFVPTIKDIFGFIGASSATMLIFILPSAFYLRLVKKEPMRSPQKIGALIFLIVGIIFMIVSMTLIVMDWIYNPPRSRHH", "length": 556, "header": "tr|E1C7L9-1|E1C7L9_CHICK Computationally mapped isoform of Solute carrier family 38 member 4 OS=Gallus gallus OX=9031 GN=SLC38A4 PE=1 SV=1 CANONICAL=A0A8V0YM52-1" }, "locus": { "chromosome": "1", "start_pos": 31259937, "end_pos": 31244752, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033692.1", "url": "https://www.ensembl.org/id/ENSGALT00010033692.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019839.1", "url": "https://www.ensembl.org/id/ENSGALP00010019839.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:417809", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417809", "resource": "KEGG Pathway" }, { "id": "R-GGA-352230", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-352230", "resource": "Reactome", "description": "Amino acid transport across the plasma membrane" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8M6YZH0-1", "protein_name": "Sodium-coupled neutral amino acid transporter 4", "gene_name": "slc38a4", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MERMELKKVSAEMEDESSVDDSYRENMDSEKATINSQFLDEDDAESQKFLTNGLMKKKKYEEYNEEYHPGHASFGMSVFNLSNAIMGSGILGLSFAMANTGIILFVILLLGVAILSLYSVHLLLVTAKEGGSLIYEKLGERAFGWPGKMAAFGSITLQNIGAMSSYLFIVKYELPEVIRAFLGLEESSGEWYLNGNYVVVLVSIGIILPLSLLKNLGYLGYTSGFSLSCMVFFLGVLIYKKTILPCPLPFFFEHGSNVSINGSDAIALYGLHNASALAYMSETAANAVDPHTPLHDSVQFSAHPEDHQDMCTPKYFIFNSQTVYTVPILAFAFVCHPEVLPIYSELKNRSRRRMQSVSNLSILAMLVMYLLSALFGYLTFYDHVEAELLHTFTKVYKFDTMLLMVRLAVLTAVTLTVPIVLFPIRSSVITLCFAGKEFSWIRHFLIAAAILAFNNLLVIFVPTIRDIFGFIGSSAATMLIFILPAAFYLRLVKSLPMKSPQKISALIFLVVGIFFMIGSLSLIVLDWIHNPPGSKGAH", "length": 538 }, "evidence": [ { "id": "A0A8V0YM52", "url": "https://omabrowser.org/oma/group/A0A8V0YM52/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0ABI0NXQ0-1", "protein_name": "Solute carrier family 38 member 4", "gene_name": "SLC38A4", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MDPMELSNVNIEPDDESISGESIQDSYTRMGNLEKAAMSSQFTNEDAESQKFLTNGFLGKKKLADYDDEHHPGTTSFGMSSFNLSNAIMGSGILGLSYAMANTGIILFIIMLLAVAVLSLYSVHLLLKTAKEGGSLIYEKLGEKAFGWPGKIGAFISITMQNIGAMSSYLFIIKYELPEVIRAFMGLEENTGEWYLNGNYLVIFVSVGIILPLSLLKNLGYLGYTSGFSLTCMVFFVSVVIYKKFQIPCPLPILDHSVGNLTFNNTVPMHVVMLLNNTESSGVNFMMDYTHQNAAGLDENQAKGSLHGSGVEFEAHSDDKCQPKYFVFNSRTAYAIPILAFAFVCHPEVLPIYSELKDRSRRKMQTVSNVSITGMLVMYLLAALFGYLTFYGEVEDELLHAYSKVYTFDTPLLMVRLAVLMAVTLTVPIVLFPIRTSVTTLLFPKRPFSWIRHFLIAAIIIALNNVLVILVPTIKYIFGFIGASSATMLIFILPAVFYLKLVKKEPFRSPQKVGALIFLVVGIIFMMGSMALIIIDWIYDPPNSKHH", "length": 547 }, "evidence": [ { "id": "A0A8V0YM52", "url": "https://omabrowser.org/oma/group/A0A8V0YM52/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q8R1S9-1", "protein_name": "Sodium-coupled neutral amino acid transporter 4", "gene_name": "Slc38a4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDPMELNNVSIEPDGDSCSGDSIQDSYTGMENSDKDAMNSQFANEDAESQKFLTNGFLGKKKLADYADEHHPGMTSFGMSSFNLSNAIMGSGILGLSYAMANTGIILFIIMLLTVAILSLYSVHLLLKTAKEGGSLIYEKLGEKAFGWPGKIGAFISITMQNIGAMSSYLFIIKYELPEVIRAFMGLEENTGEWYLNGNYLVLFVSVGIILPLSLLKNLGYLGYTSGFSLSCMVFFVSVVIYKKFQIPCPLPALDHNNGNLTFNNTLPIHMISLPNDSESSGVNFMMDYAHHNPAGLDEKQVAGPLHSNGVEYEAQGAEKCQPKYFVFNSRTAYAIPILAFAFVCHPEVLPIYSELKDRSRRKMQTVSNISISGMLVMYLLAALFGYLSFYGDVEDELLHAYSKVYTFDTALLMVRLAVLVAVTLTVPIVLFPIRTSVITLLFPRKPFSWLKHFGIAAIIIALNNILVILVPTIKYIFGFIGASSATMLIFILPAAFYLKLVKKEPLRSPQKIGALVFLVTGIIFMMGSMALIILDWIYNPPNPNHH", "length": 547 }, "evidence": [ { "id": "A0A8V0YM52", "url": "https://omabrowser.org/oma/group/A0A8V0YM52/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q969I6-1", "protein_name": "Sodium-coupled neutral amino acid transporter 4", "gene_name": "SLC38A4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDPMELRNVNIEPDDESSSGESAPDSYIGIGNSEKAAMSSQFANEDTESQKFLTNGFLGKKKLADYADEHHPGTTSFGMSSFNLSNAIMGSGILGLSYAMANTGIILFIIMLLAVAILSLYSVHLLLKTAKEGGSLIYEKLGEKAFGWPGKIGAFVSITMQNIGAMSSYLFIIKYELPEVIRAFMGLEENTGEWYLNGNYLIIFVSVGIILPLSLLKNLGYLGYTSGFSLTCMVFFVSVVIYKKFQIPCPLPVLDHSVGNLSFNNTLPMHVVMLPNNSESSDVNFMMDYTHRNPAGLDENQAKGSLHDSGVEYEAHSDDKCEPKYFVFNSRTAYAIPILVFAFVCHPEVLPIYSELKDRSRRKMQTVSNISITGMLVMYLLAALFGYLTFYGEVEDELLHAYSKVYTLDIPLLMVRLAVLVAVTLTVPIVLFPIRTSVITLLFPKRPFSWIRHFLIAAVLIALNNVLVILVPTIKYIFGFIGASSATMLIFILPAVFYLKLVKKETFRSPQKVGALIFLVVGIFFMIGSMALIIIDWIYDPPNSKHH", "length": 547 }, "evidence": [ { "id": "A0A8V0YM52", "url": "https://omabrowser.org/oma/group/A0A8V0YM52/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9EQ25-1", "protein_name": "Sodium-coupled neutral amino acid transporter 4", "gene_name": "Slc38a4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDPIELRSVNIEPYEDSCSVDSIQSCYTGMGNSEKGAMDSQFANEDAESQKFLTNGFLGKKTLTDYADEHHPGTTSFGMSSFNLSNAIMGSGILGLSYAMANTGIVLFVIMLLTVAILSLYSVHLLLKTAKEGGSLIYEKLGEKAFGWPGKIGAFISITMQNIGAMSSYLFIIKYELPEVIRVFMGLEENTGEWYLNGNYLVLFVSVGIILPLSLLKNLGYLGYTSGFSLTCMVFFVSVVIYKKFQIPCPLPVLDHNNGNLTFNNTLPMHVIMLPNNSESTGMNFMVDYTHRDPEGLDEKPAAGPLHGSGVEYEAHSGDKCQPKYFVFNSRTAYAIPILAFAFVCHPEVLPIYSELKDRSRRKMQTVSNISITGMLVMYLLAALFGYLSFYGEVEDELLHAYSKVYTFDTALLMVRLAVLVAVTLTVPIVLFPIRTSVITLLFPRRPFSWVKHFGIAAIIIALNNVLVILVPTIKYIFGFIGASSATMLIFILPAAFYLKLVKKEPLRSPQKIGALVFLVTGIIFMMGSMALIIIDWIYNPPNPDHH", "length": 547 }, "evidence": [ { "id": "A0A8V0YM52", "url": "https://omabrowser.org/oma/group/A0A8V0YM52/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "L-amino acid transmembrane transporter activity", "id": "GO:0015179", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015179", "evidence": [ { "database": "UniProtKB", 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"length": 1029, "header": "tr|A0A8V0YM92-1|A0A8V0YMA3_CHICK Computationally mapped isoform of Calcium voltage-gated channel auxiliary subunit alpha2delta 4 OS=Gallus gallus OX=9031 GN= PE=3 SV=1 CANONICAL=A0A8V0YMA3-1" }, "locus": { "chromosome": "1", "start_pos": 61145467, "end_pos": 61031527, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033441.1", "url": "https://www.ensembl.org/id/ENSGALT00010033441.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019727.1", "url": "https://www.ensembl.org/id/ENSGALP00010019727.1" } ] } }, { "isoform_ac": "A0A8V0YM98-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMA3/entry#A0A8V0YM98-1", "sequence": { "sequence": 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"length": 1040, "header": "tr|A0A8V0YM98-1|A0A8V0YM98_CHICK Computationally mapped isoform of Calcium voltage-gated channel auxiliary subunit alpha2delta 4 OS=Gallus gallus OX=9031 GN= PE=3 SV=1 CANONICAL=A0A8V0YMA3-1" }, "locus": { "chromosome": "1", "start_pos": 61145467, "end_pos": 61031102, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033453.1", "url": "https://www.ensembl.org/id/ENSGALT00010033453.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019732.1", "url": "https://www.ensembl.org/id/ENSGALP00010019732.1" } ] } }, { "isoform_ac": "A0A8V0YMA3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMA3/entry#A0A8V0YMA3-1", "sequence": { "sequence": "MTGTWRMDRGAIPLLLLSFLCLLPAAQLQTKIPLETVKSWADAFGGELYSIVTKYSGSLLLQKKYKDVEPTLKIKEVDGLELVKKFSEQMESMLRRKVEAVERLVEAAEDADLNHEYNSSLEFDYYNSLLINEKDENDNYVELGDEFILEPNEHFNNLLVNTTYSDIQLPTNVYNKDPDILNGVYMSEALNPVFVDNFERDPTLTWQYFGSSTGFFRLYPGIKWLPDENGVISFDCRNRGWYIQAATSPKDIVIIVDVSGSMKGLRMTIAKHTIVTILDTLGENDFVNIIAYNDYVHFIEPCFKGILVQADRDNREHFKQLVDELQAKGVGTVNKALTESFKILREFRDAGQGGLCNQAIMLITDGAVEDYEAVFEKYNWPDRKVRVFTYLIGREVTFAPNVKWIACNNKGYYTQISTLADVQENVMEYLHVLSRPMVINHDHDIIWTEAYMDSALFASQAQSLLLMTTVAMPVFSKKNETRSHGILLGVVGSDVPLRELLKLAPRYKLGVHGYAFLNTNNGYILSHPDLRPLYKEGKKLKPKPNYNSVDLSEVEWEDQDEILRTAMINGETGYLSMDVKVPVDKGKRVLFLTNDYFFTDISGTPFSLGVVLSRGHGEYILLGNTSVEEGLHDLLQPDLSLANEWIYCITDIDPDHRKLSQLEAVIRFLTGEEPDLECDEELVQEVLFDAVVTAPMEAYWTTLALNMSTESEAGVEMAFLGTRAGLMRSALYVGSEKLSNRKFLTRKDKESIFTMDHFPLWYRRAAEHPPGSFIYSIVSEDDSEGGGLPKVVTVSTAVAVSVDGKMGIAAAVGVQIKLELLQRKFWMAMQQPNDTDCSAFDGACPLSCQDDVLNCFLIDNNGFILVSKRPPEIGKFLGVVDGSVMTQLLNMGMFRRVTMYDYQAMCKVPYHHHSGARPLLSPIYAFLAALKWLISDFLIFLLEFNMSSFWHSENVADAHKHKKHDTLQPCDTEYPVFVYEPAIKETNGLIECGDCQKMFVAQQIASSNLLLLVTDATCDCSIFPPVLLDAKEVKYILLLRAFGLRADEGGKPAPLAVPMGEGVEGTACPWDSRRQGNGAACRRRGKQCCCWALCMHFCHPQPLVIPCLLLAPAGLPAHTPATCGWEAAALSWPTLL", "length": 1136, "header": "tr|A0A8V0YMA3-1|A0A8V0YMA3_CHICK Isoform 1 of Calcium voltage-gated channel auxiliary subunit alpha2delta 4 OS=Gallus gallus OX=9031 GN= PE=3 SV=1 CANONICAL=A0A8V0YMA3-1" }, "locus": { "chromosome": "1", "start_pos": 61145467, "end_pos": 61031221, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033463.1", "url": "https://www.ensembl.org/id/ENSGALT00010033463.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019737.1", "url": "https://www.ensembl.org/id/ENSGALP00010019737.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "calcium channel activity", "id": "GO:0005262", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005262", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMA3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMA3" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMA3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMA3" } ], "pmid": "" }, { "name": "voltage-gated calcium channel activity", "id": "GO:0005245", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005245", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMA3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMA3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "monoatomic ion channel complex", "id": "GO:0034702", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034702", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMA3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMA3" } ], "pmid": "" }, { "name": "voltage-gated calcium channel complex", "id": "GO:0005891", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005891", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMA3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMA3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "detection of light stimulus involved in visual perception", "id": "GO:0050908", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050908", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMA3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMA3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 118, "end_pos": 120, "annotation": "n_glycosylation_sequon" }, { "start_pos": 161, "end_pos": 163, "annotation": "n_glycosylation_sequon" }, { "start_pos": 479, "end_pos": 481, "annotation": "n_glycosylation_sequon" }, { "start_pos": 624, "end_pos": 626, "annotation": "n_glycosylation_sequon" }, { "start_pos": 706, "end_pos": 708, "annotation": "n_glycosylation_sequon" }, { "start_pos": 833, "end_pos": 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0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YM97-1", "uniprot_ac": "A0A8V0YM97", "uniprot_id": "A0A8V0YM97_CHICK", "mass": { "chemical_mass": 105344.0, "monoisotopic_mass": 105344.0 }, "refseq": { "ac": "XP_015133396", "name": "chromosome alignment-maintaining phosphoprotein 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015133396" }, "gene_names": [ { "name": "CHAMP1", "type": "recommended", "evidence": [ { "id": "A0A8V0YM97", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM97" } ] }, { "name": "CHAMP1", "type": "synonym", "evidence": [ { "id": "XP_015133396", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015133396" } ] } ], "protein_names": [ { "name": "Chromosome alignment-maintaining phosphoprotein 1", "type": "recommended", "evidence": [ { "id": "A0A8V0YM97", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM97/entry#names_and_taxonomy" } ] }, { "name": "Zinc finger protein 828", "type": "synonym", "evidence": [ { "id": "A0A8V0YM97", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM97/entry#names_and_taxonomy" } ] }, { "name": "chromosome alignment-maintaining phosphoprotein 1", "type": "synonym", "evidence": [ { "id": "XP_015133396", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015133396" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015133396.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015133396", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015133396" } ] }, { "annotation": "Required for proper alignment of chromosomes at metaphase and their accurate segregation during mitosis. Involved in the maintenance of spindle microtubules attachment to the kinetochore during sister chromatid biorientation. May recruit CENPE and CENPF to the kinetochore.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YM97", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM97#function" }, { "database": "UniProtKB", "id": "ARBA00054834", "url": "https://www.uniprot.org/uniprotkb/ARBA00054834#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YM97", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM97" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CHAMP1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM97", "locus": { "chromosome": "1", "start_pos": 136910295, "end_pos": 136921996, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013398", "url": "https://www.ensembl.org/id/ENSGALG00010013398" } ] } } ], "crossref": [ { "id": "418733", "url": "https://www.ncbi.nlm.nih.gov/gene/418733", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039330", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039330", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:418733", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418733", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WKPIPSI", "url": "https://omabrowser.org/oma/group/WKPIPSI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YM97", "url": "https://www.orthodb.org/?gene=A0A8V0YM97", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR37354", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR37354", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR37354:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR37354:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "XP_015133396", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015133396", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YM97", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM97", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YM97-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM97-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDMLQILRKTTERLECDHCSFRGTDYENIQIHMGTIHPEYCDEMDAAGLGKLIFYQKSAKLFHCHKCFFTSKMYCNVYYHITAQHAAPEKWNEERKGQVEGGSDSSKKNGAAEPQKCTPPPESLKPALSPEVPKPESKLQKSSVSPESQKSAQTSSSEPERSAQIMSPDSEKSVQAVSPDPEKLVSAVSSDSEKSSPDASPDPQKQSPDASPDPQKPAPAVSPDPQKPAVAVSPEPRRHSPAVSPEPRRHSPAMSPEPRRHSPAVSPEPRRHSPAVSPEPRRYSPGVSPEPKKPTPAVSPEPRRYSPAVSPEPRRHASQMRRPASASSPEIRRPAPAVSPESWRPGPTVSPEPWRSTPHEMQKSSTVSPWAPKASIESRRSAPESRRSGPVASPESRRLVSDSWKSTSFSESQKSTLVSTEPWKPISSVYPEGWKPVLSPDTWKHSSSVSPELRKSSHAVSSDSWKPSFFPEVRKPATSVSPESWKLSESRKSMFFSETQKSTSAASFEVQKRSHFPEPRKRALFPESRKSNPAVSTDVQKRAVFSETQNKVSASLASTEGQKHALCSEAQKSALVSPEVQKHALFSEAQKLAPISPEVQDHTSFLESQKSASPEIQKHGLFNEAHKQAHSASPDTQKQALFPDSQKSAVSPDIQKQAVFSEMQKPAASMSSDIQRHTETTVPSELPKNILFSESHKCVPGFSSEPQTPSESGESDFLSHTLDDQKPLDDLFSPDEQSILAKESPEDMLYSCPKKKPRKENQDNSDSELNSSECGKAEMDSMEMKEQESNSDQEQYDMESSDYSRESKIDAATPTQPQCVLQFTEEKEAFISEEEIAKYMKRGKGKYYCKICCCRAMKKGAVLHHLVNKHNVQSPYKCKICGKAFLLESLLKNHVAAHGQSLLKCPRCNFESNFPRGFKKHLTHCQSRHNDDTPKKHLDSLEPLEEQI", "length": 948, "header": "tr|A0A8V0YM97-1|A0A8V0YM97_CHICK Isoform 1 of Chromosome alignment-maintaining phosphoprotein 1 OS=Gallus gallus OX=9031 GN=CHAMP1 PE=1 SV=1 CANONICAL=A0A8V0YM97-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YM97-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM97/entry#A0A8V0YM97-1", "sequence": { "sequence": "MDMLQILRKTTERLECDHCSFRGTDYENIQIHMGTIHPEYCDEMDAAGLGKLIFYQKSAKLFHCHKCFFTSKMYCNVYYHITAQHAAPEKWNEERKGQVEGGSDSSKKNGAAEPQKCTPPPESLKPALSPEVPKPESKLQKSSVSPESQKSAQTSSSEPERSAQIMSPDSEKSVQAVSPDPEKLVSAVSSDSEKSSPDASPDPQKQSPDASPDPQKPAPAVSPDPQKPAVAVSPEPRRHSPAVSPEPRRHSPAMSPEPRRHSPAVSPEPRRHSPAVSPEPRRYSPGVSPEPKKPTPAVSPEPRRYSPAVSPEPRRHASQMRRPASASSPEIRRPAPAVSPESWRPGPTVSPEPWRSTPHEMQKSSTVSPWAPKASIESRRSAPESRRSGPVASPESRRLVSDSWKSTSFSESQKSTLVSTEPWKPISSVYPEGWKPVLSPDTWKHSSSVSPELRKSSHAVSSDSWKPSFFPEVRKPATSVSPESWKLSESRKSMFFSETQKSTSAASFEVQKRSHFPEPRKRALFPESRKSNPAVSTDVQKRAVFSETQNKVSASLASTEGQKHALCSEAQKSALVSPEVQKHALFSEAQKLAPISPEVQDHTSFLESQKSASPEIQKHGLFNEAHKQAHSASPDTQKQALFPDSQKSAVSPDIQKQAVFSEMQKPAASMSSDIQRHTETTVPSELPKNILFSESHKCVPGFSSEPQTPSESGESDFLSHTLDDQKPLDDLFSPDEQSILAKESPEDMLYSCPKKKPRKENQDNSDSELNSSECGKAEMDSMEMKEQESNSDQEQYDMESSDYSRESKIDAATPTQPQCVLQFTEEKEAFISEEEIAKYMKRGKGKYYCKICCCRAMKKGAVLHHLVNKHNVQSPYKCKICGKAFLLESLLKNHVAAHGQSLLKCPRCNFESNFPRGFKKHLTHCQSRHNDDTPKKHLDSLEPLEEQI", "length": 948, "header": "tr|A0A8V0YM97-1|A0A8V0YM97_CHICK Isoform 1 of Chromosome alignment-maintaining phosphoprotein 1 OS=Gallus gallus OX=9031 GN=CHAMP1 PE=1 SV=1 CANONICAL=A0A8V0YM97-1" }, "locus": { "chromosome": "1", "start_pos": 136914790, "end_pos": 136911947, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032261.1", "url": "https://www.ensembl.org/id/ENSGALT00010032261.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019051.1", "url": "https://www.ensembl.org/id/ENSGALP00010019051.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 295, "start_aa": "Thr", "end_pos": 295, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr295", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 348, "start_aa": "Thr", "end_pos": 348, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr348", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:418733", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418733", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0AAA9SEB0-1", "protein_name": "Chromosome alignment-maintaining phosphoprotein 1", "gene_name": "CHAMP1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MEVFQELRKTSARLECDHCNFRGTDYENVQIHMGTIHPEFCDEMDAGGLGKMIFYQKSAKLFHCHKCFFTSKMYSNVYYHITAKHSAAEKWNEKPKNQFNKEGEPVKSPPLPEHQKTASSSAELLKPAPALSIETQKLGPVASPESPEPAPLPSLDSQKPGPVVSPEPQTPSLPSPEPPKPAPVSSPELPKPAPLVSESQKLVPVPSPEPQKLAPVSPEPIKATLTNPKPQKHSHFPETLVPPSAPSPESPVLAASPEPWGPSPTASPESRKPAQTVSPEPRKLSPSVSPEPWKLFSAVSSEPRRPAPSVSPGSWKPGPPGSPRSWKSSPSAASGPWKPAKPAPSVSPGPWKPTPSMSSASWKSSSVSSGSWKSPPASPESWKSGPPELRKTATTLSPEHWKTVPPESPELRKPGPTLSPEIRSPAGSPELRKPSGSPEIWKFSPDQRKTSPASVDYPESQKSSRGGSPDLWKSSFFIEPQKPVFPEIRKPGPSGPSESPKAASDIWKPVLSVSTEPRKPSLFSEPTKTAPPASPEPRKRALFPEPRKHALFPELPKSAIFSESQKVVELGDEPQADAIDDQKCDVLVQEELMATPKKLLEDTLFPSSKKLKKDSQENSDAELSSSECIKADLDAVDGKGQESSSDQEQVDVESIDFSKENKMDITSPEQSKNVLQFTEEKEAFISEEEIAKYMKRGKGKYYCKICCCRAMKKGAVLHHLVNKHNVHSPYKCTICGKAFLLESLLKNHVAAHGQSLLKCPRCNFESNFPRGFKKHLTHCQSRHNEEANKKLMEALEPPLEEQQI", "length": 804 }, "evidence": [ { "id": "A0A8V0YM97", "url": "https://omabrowser.org/oma/group/A0A8V0YM97/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q8K327-1", "protein_name": "Chromosome alignment-maintaining phosphoprotein 1", "gene_name": "Champ1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEVCQELRKPALSLECGHCSFRGTDYENVQLHMGSIHPEFCDDMDAGGLGKLIFYQKSAKLFHCHKCFFTSKLYANVYYHITARHAASDKWSEQPKEQPSKDTESGKSPSPPERQNPAFDPAEARPTPALPMEAQKTSPSLCPESQASGPPVLEPQGAGPLISPEPQAPCLPAEASKAAPVPCPERVDPPCELPELEKPERGPSPESVKSALVSSKPPKHSSFADTGAAPSALSPESPVLATSPEPWGPSLSASPESRKPARTASPEPRKPSPAESPELWKPFPAIASEPRRPTPAVSPGSWKPGPPGSPRPWKSSPSATSGPWKSSKPVQPMSPGPWKPIPSVSPGPWKPAPSMSTASWKSSVSSGSWKTPPTSPESWKSGPPELRKTALPLSPEHWKAVPPVSPELRRPGPPLSPEIRSPAGSPELKKPSSSPDLWKVSPDQRKTSPASLDFPEPQKSSCGSPPDLWKSSFIMESQKPNVFSETRKHTASGSSESPKVASDIWKPVLSIDAEPRKSTLFPEPTKAVLPASPEPRKRALFPESRKHVFLPELPKSAVFSDAQKAPELSEEIQLEAVDNAKCDSLAQEGLLATPKKLLDEALSPSSKKLKKDSQENSDAELSSSEYIRADLDTLDTKGQESSSDQEQVDVESIDFSKENKMEMGSTEQAKNVLQFTEEKEAFISEEEIAKYMKRGKGKYYCKICCCRAMKKGAVLHHLVNKHNVHSPYKCTICGKAFLLESLLKNHVAAHGQSLLKCPRCNFESNFPRGFKKHLTHCQSRHNEEVNKKLMEALESPLEEQQI", "length": 802 }, "evidence": [ { "id": "A0A8V0YM97", "url": "https://omabrowser.org/oma/group/A0A8V0YM97/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96JM3-1", "protein_name": "Chromosome alignment-maintaining phosphoprotein 1", "gene_name": "CHAMP1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEAFQELRKPSARLECDHCSFRGTDYENVQIHMGTIHPEFCDEMDAGGLGKMIFYQKSAKLFHCHKCFFTSKMYSNVYYHITSKHASPDKWNDKPKNQLNKETDPVKSPPLPEHQKIPCNSAEPKSIPALSMETQKLGSVLSPESPKPTPLTPLEPQKPGSVVSPELQTPLPSPEPSKPASVSSPEPPKSVPVCESQKLAPVPSPEPQKPAPVSPESVKATLSNPKPQKQSHFPETLGPPSASSPESPVLAASPEPWGPSPAASPESRKSARTTSPEPRKPSPSESPEPWKPFPAVSPEPRRPAPAVSPGSWKPGPPGSPRPWKSNPSASSGPWKPAKPAPSVSPGPWKPIPSVSPGPWKPTPSVSSASWKSSSVSPSSWKSPPASPESWKSGPPELRKTAPTLSPEHWKAVPPVSPELRKPGPPLSPEIRSPAGSPELRKPSGSPDLWKLSPDQRKTSPASLDFPESQKSSRGGSPDLWKSSFFIEPQKPVFPETRKPGPSGPSESPKAASDIWKPVLSIDTEPRKPALFPEPAKTAPPASPEARKRALFPEPRKHALFPELPKSALFSESQKAVELGDELQIDAIDDQKCDILVQEELLASPKKLLEDTLFPSSKKLKKDNQESSDAELSSSEYIKTDLDAMDIKGQESSSDQEQVDVESIDFSKENKMDMTSPEQSRNVLQFTEEKEAFISEEEIAKYMKRGKGKYYCKICCCRAMKKGAVLHHLVNKHNVHSPYKCTICGKAFLLESLLKNHVAAHGQSLLKCPRCNFESNFPRGFKKHLTHCQSRHNEEANKKLMEALEPPLEEQQI", "length": 812 }, "evidence": [ { "id": "A0A8V0YM97", "url": "https://omabrowser.org/oma/group/A0A8V0YM97/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "attachment of mitotic spindle microtubules to kinetochore", "id": "GO:0051315", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051315", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YM97", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM97" } ], "pmid": "" }, { "name": "protein localization to kinetochore", "id": "GO:0034501", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034501", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YM97", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM97" } ], "pmid": "" }, { "name": "sister chromatid biorientation", "id": "GO:0031134", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031134", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YM97", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM97" } ], "pmid": "" }, { "name": "protein localization to microtubule", "id": "GO:0035372", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035372", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YM97", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM97" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "spindle", "id": "GO:0005819", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005819", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YM97", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM97" } ], "pmid": "" }, { "name": "nuclear body", "id": "GO:0016604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016604", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YM97", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM97" } ], "pmid": "" }, { "name": "kinetochore", "id": "GO:0000776", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000776", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YM97", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM97" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YM97", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM97" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 770, "end_pos": 772, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YM97", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM97" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 876, "end_pos": 898, "start_aa": "Tyr", "end_aa": "His", "glycosite_overlap": "" } ], "binding_sites": 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"id": "A0A8V0X1Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X1Q7" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0X1Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X1Q7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0X1Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X1Q7" } ] } ] }, { "uniprot_ac": "A0A8V0X2Y2", "gene_name": "MAPK12", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X2Y2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X2Y2" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0X2Y2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X2Y2" } ] } ] }, { "uniprot_ac": "A0A8V0X3D6", "gene_name": "LOC100858386", "activity": [ { "ec_number": 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O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X4Q3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X4Q3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0X4Q3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X4Q3" } ] } ] }, { "uniprot_ac": "A0A8V0X5Z8", "gene_name": "NEK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X5Z8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X5Z8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0X5Z8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X5Z8" } ] } ] }, { "uniprot_ac": "A0A8V0X6T4", "gene_name": "LOC107050692", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X6T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X6T4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0X6T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X6T4" } ] } ] }, { "uniprot_ac": "A0A8V0X7R2", "gene_name": "SBK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X7R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X7R2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0X7R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X7R2" } ] } ] }, { "uniprot_ac": "A0A8V0X8M1", "gene_name": "TRIO", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X8M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X8M1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0X8M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X8M1" } ] } ] }, { "uniprot_ac": "A0A8V0XAH9", "gene_name": "NEK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XAH9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XAH9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XAH9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XAH9" } ] } ] }, { "uniprot_ac": "A0A8V0XB58", "gene_name": "CAMK2D", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XB58", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XB58" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V0XB58", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XB58" } ] } ] }, { "uniprot_ac": "A0A8V0XBZ0", "gene_name": "STK32C", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XBZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XBZ0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XBZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XBZ0" } ] } ] }, { "uniprot_ac": "A0A8V0XCS0", "gene_name": "PRKG2", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XCS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCS0" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "A0A8V0XCS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCS0" } ] } ] }, { "uniprot_ac": "A0A8V0XCV5", "gene_name": "MAP3K7", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XCV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCV5" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0XCV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCV5" } ] } ] }, { "uniprot_ac": "A0A8V0XCY6", "gene_name": "TTK", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XCY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCY6" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V0XCY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCY6" } ] } ] }, { "uniprot_ac": "A0A8V0XDR5", "gene_name": "IRAK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XDR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XDR5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XDR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XDR5" } ] } ] }, { "uniprot_ac": "A0A8V0XE48", "gene_name": "ROCK2", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XE48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XE48" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "A0A8V0XE48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XE48" } ] } ] }, { "uniprot_ac": "A0A8V0XEA3", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XEA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEA3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XEA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEA3" } ] } ] }, { "uniprot_ac": "A0A8V0XFW1", "gene_name": "SGK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XFW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XFW1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XFW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XFW1" } ] } ] }, { "uniprot_ac": "A0A8V0XFX2", "gene_name": "NEK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XFX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XFX2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XFX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XFX2" } ] } ] }, { "uniprot_ac": "A0A8V0XG21", "gene_name": "LOC107050335", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XG21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XG21" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XG21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XG21" } ] } ] }, { "uniprot_ac": "A0A8V0XI18", "gene_name": "ATM", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XI18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XI18" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XI18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XI18" } ] } ] }, { "uniprot_ac": "A0A8V0XKG0", "gene_name": "NEK9", "activity": [ { "ec_number": "2.7.11.38", "activity": "L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XKG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XKG0" } ] }, { "ec_number": "2.7.11.38", "activity": "", "evidence": [ { "id": "A0A8V0XKG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XKG0" } ] } ] }, { "uniprot_ac": "A0A8V0XLV6", "gene_name": "MAPK10", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XLV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XLV6" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0XLV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XLV6" } ] } ] }, { "uniprot_ac": "A0A8V0XMT1", "gene_name": "MOS", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XMT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMT1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XMT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMT1" } ] } ] }, { "uniprot_ac": "A0A8V0XMX8", "gene_name": "MASTL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XMX8", "database": "UniProtKB", "url": 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"ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XNJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNJ2" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0XNJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNJ2" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A8V0XNJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNJ2" } ] } ] }, { "uniprot_ac": "A0A8V0XNK8", "gene_name": "PRKCQ", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XNK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNK8" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V0XNK8", "database": "UniProtKB", "url": 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"uniprot_ac": "A0A8V0XQQ4", "gene_name": "NME7", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQQ4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQQ4" } ] } ] }, { "uniprot_ac": "A0A8V0XQS0", "gene_name": "STK24", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XQS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQS0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XQS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQS0" } ] } ] }, { "uniprot_ac": "A0A8V0XS42", "gene_name": "MAP3K4", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XS42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XS42" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0XS42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XS42" } ] } ] }, { "uniprot_ac": "A0A8V0XU71", "gene_name": "MYO3A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XU71", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XU71" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XU71", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XU71" } ] } ] }, { "uniprot_ac": "A0A8V0XU96", "gene_name": "PRKD1", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XU96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XU96" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V0XU96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XU96" } ] } ] }, { "uniprot_ac": "A0A8V0XUM6", "gene_name": "LATS1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XUM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XUM6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XUM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XUM6" } ] } ] }, { "uniprot_ac": "A0A8V0XW11", "gene_name": "RPS6KA2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XW11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XW11" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XW11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XW11" } ] } ] }, { "uniprot_ac": "A0A8V0XW29", "gene_name": "CDKL2", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XW29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XW29" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0XW29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XW29" } ] } ] }, { "uniprot_ac": "A0A8V0XXB8", "gene_name": "MAPK15", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XXB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XXB8" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0XXB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XXB8" } ] } ] }, { "uniprot_ac": "A0A8V0Y074", "gene_name": "NEK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y074", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y074" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y074", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y074" } ] } ] }, { "uniprot_ac": "A0A8V0Y241", "gene_name": "LOC426385", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y241", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y241" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y241", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y241" } ] } ] }, { "uniprot_ac": "A0A8V0Y2I5", "gene_name": "CDK7", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] }, { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] } ] }, { "uniprot_ac": "A0A8V0Y3D1", "gene_name": "LRRK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y3D1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y3D1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y3D1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y3D1" } ] } ] }, { "uniprot_ac": "A0A8V0Y3L2", "gene_name": "MLK4", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y3L2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y3L2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0Y3L2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y3L2" } ] } ] }, { "uniprot_ac": "A0A8V0Y457", "gene_name": "PRPF4B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y457", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y457" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y457", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y457" } ] } ] }, { "uniprot_ac": "A0A8V0Y4L8", "gene_name": "HUNK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y4L8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y4L8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y4L8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y4L8" } ] } ] }, { "uniprot_ac": "A0A8V0Y6K1", "gene_name": "MAK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y6K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y6K1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y6K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y6K1" } ] } ] }, { "uniprot_ac": "A0A8V0Y7C3", "gene_name": "DAPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y7C3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y7C3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y7C3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y7C3" } ] } ] }, { "uniprot_ac": "A0A8V0Y823", "gene_name": "SRPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y823", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y823" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y823", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y823" } ] } ] }, { "uniprot_ac": "A0A8V0Y8X9", "gene_name": "PRKACA", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y8X9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y8X9" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "A0A8V0Y8X9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y8X9" } ] } ] }, { "uniprot_ac": "A0A8V0Y935", "gene_name": "MAST4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y935", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y935" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y935", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y935" } ] } ] }, { "uniprot_ac": "A0A8V0Y955", "gene_name": "PAK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y955", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y955" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y955", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y955" } ] } ] }, { "uniprot_ac": "A0A8V0Y9Q1", "gene_name": "LOC107055388", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y9Q1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9Q1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y9Q1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9Q1" } ] } ] }, { "uniprot_ac": "A0A8V0YCV9", "gene_name": "SIK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YCV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCV9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YCV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCV9" } ] } ] }, { "uniprot_ac": "A0A8V0YCY4", "gene_name": "AURKB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YCY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCY4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YCY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCY4" } ] } ] }, { "uniprot_ac": "A0A8V0YCY8", "gene_name": "RIOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YCY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCY8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YCY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCY8" } ] } ] }, { "uniprot_ac": "A0A8V0YDH4", "gene_name": "ALPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YDH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDH4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YDH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDH4" } ] } ] }, { "uniprot_ac": "A0A8V0YF83", "gene_name": "WNK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YF83", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF83" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YF83", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF83" } ] } ] }, { "uniprot_ac": "A0A8V0YFH4", "gene_name": "NRK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YFH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFH4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YFH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFH4" } ] } ] }, { "uniprot_ac": "A0A8V0YFL1", "gene_name": "CDK19", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YFL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFL1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0YFL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFL1" } ] } ] }, { "uniprot_ac": "A0A8V0YFP8", "gene_name": "RIPK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YFP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFP8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YFP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFP8" } ] } ] }, { "uniprot_ac": "A0A8V0YFR6", "gene_name": "TNIK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YFR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFR6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YFR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFR6" } ] } ] }, { "uniprot_ac": "A0A8V0YGW2", "gene_name": "STK32B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YGW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGW2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YGW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGW2" } ] } ] }, { "uniprot_ac": "A0A8V0YHH2", "gene_name": "STK38L", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YHH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHH2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YHH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHH2" } ] } ] }, { "uniprot_ac": "A0A8V0YHN2", "gene_name": "RPS6KA1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YHN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHN2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YHN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHN2" } ] } ] }, { "uniprot_ac": "A0A8V0YIV6", "gene_name": "DYRK1A", "activity": [ { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] }, { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] } ] }, { "uniprot_ac": "A0A8V0YJP9", "gene_name": "RIOK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YJP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJP9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YJP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJP9" } ] } ] }, { "uniprot_ac": "A0A8V0YK18", "gene_name": "CDC42BPB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YK18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK18" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YK18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK18" } ] } ] }, { "uniprot_ac": "A0A8V0YKK3", "gene_name": "MAP4K4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YKK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKK3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YKK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKK3" } ] } ] }, { "uniprot_ac": "A0A8V0YLV1", "gene_name": "MARK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YLV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLV1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YLV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLV1" } ] } ] }, { "uniprot_ac": "A0A8V0YM22", "gene_name": "MYO3AL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YM22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM22" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YM22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM22" } ] } ] }, { "uniprot_ac": "A0A8V0YM96", "gene_name": "STK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YM96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM96" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YM96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM96" } ] } ] }, { "uniprot_ac": "A0A8V0YMB3", "gene_name": "STK32A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YMB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMB3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YMB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMB3" } ] } ] }, { "uniprot_ac": "A0A8V0YMN5", "gene_name": "BRAF", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YMN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMN5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YMN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMN5" } ] } ] }, { "uniprot_ac": "A0A8V0YNI5", "gene_name": "NIM1K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YNI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNI5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YNI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNI5" } ] } ] }, { "uniprot_ac": "A0A8V0YRC9", "gene_name": "TNK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YRC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRC9" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YRC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRC9" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0YRC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRC9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YRC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRC9" } ] } ] }, { "uniprot_ac": "A0A8V0YRN4", "gene_name": "GAK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YRN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRN4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YRN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRN4" } ] } ] }, { "uniprot_ac": "A0A8V0YSH3", "gene_name": "RPS6KA6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YSH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSH3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YSH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSH3" } ] } ] }, { "uniprot_ac": "A0A8V0YTI1", "gene_name": "TSSK6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTI1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTI1" } ] } ] }, { "uniprot_ac": "A0A8V0YTL9", "gene_name": "VRK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTL9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTL9" } ] } ] }, { "uniprot_ac": "A0A8V0YTN5", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTN5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTN5" } ] } ] }, { "uniprot_ac": "A0A8V0YTP2", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTP2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTP2" } ] } ] }, { "uniprot_ac": "A0A8V0YXZ5", "gene_name": "CDC42BPA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YXZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXZ5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YXZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXZ5" } ] } ] }, { "uniprot_ac": "A0A8V0YYX2", "gene_name": "PAK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YYX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYX2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YYX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYX2" } ] } ] }, { "uniprot_ac": "A0A8V0YYZ3", "gene_name": "SPEG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YYZ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYZ3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YYZ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYZ3" } ] } ] }, { "uniprot_ac": "A0A8V0YZ74", "gene_name": "MAP2K5", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZ74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZ74" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V0YZ74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZ74" } ] } ] }, { "uniprot_ac": "A0A8V0YZF2", "gene_name": "PAK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZF2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YZF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZF2" } ] } ] }, { "uniprot_ac": "A0A8V0YZK0", "gene_name": "MAP3K6", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZK0" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0YZK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZK0" } ] } ] }, { "uniprot_ac": "A0A8V0YZM1", "gene_name": "MOK", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZM1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0YZM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZM1" } ] }, { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZM1" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0YZM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZM1" } ] } ] }, { "uniprot_ac": "A0A8V0YZV9", "gene_name": "ATR", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZV9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YZV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZV9" } ] } ] }, { "uniprot_ac": "A0A8V0YZY4", "gene_name": "SBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZY4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YZY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZY4" } ] } ] }, { "uniprot_ac": "A0A8V0Z124", "gene_name": "VRK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z124", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z124" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z124", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z124" } ] } ] }, { "uniprot_ac": "A0A8V0Z157", "gene_name": "MARK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z157", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z157" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z157", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z157" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A8V0Z157", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z157" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": 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O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z6K4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6K4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z6K4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6K4" } ] } ] }, { "uniprot_ac": "A0A8V0Z6T1", "gene_name": "ERN2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z6T1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6T1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z6T1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6T1" } ] } ] }, { "uniprot_ac": "A0A8V0Z807", "gene_name": "NEK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": 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} ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZFM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFM2" } ] } ] }, { "uniprot_ac": "A0A8V0ZFP1", "gene_name": "TTBK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZFP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFP1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZFP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFP1" } ] } ] }, { "uniprot_ac": "A0A8V0ZFT3", "gene_name": "LRRK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZFT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFT3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZFT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFT3" } ] } ] }, { "uniprot_ac": "A0A8V0ZGY3", "gene_name": "HIPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZGY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGY3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZGY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGY3" } ] } ] }, { "uniprot_ac": "A0A8V0ZH91", "gene_name": "WNK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZH91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH91" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZH91", "database": "UniProtKB", "url": 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"uniprot_ac": "A0A8V0ZKA2", "gene_name": "EIF2AK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZKA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKA2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZKA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKA2" } ] } ] }, { "uniprot_ac": "A0A8V0ZKM9", "gene_name": "STK36", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZKM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKM9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZKM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKM9" } ] } ] }, { "uniprot_ac": "A0A8V0ZLU3", "gene_name": "TLK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZLU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLU3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZLU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLU3" } ] } ] }, { "uniprot_ac": "A0A8V0ZMK1", "gene_name": "PIKFYVE", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZMK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMK1" } ] }, { "ec_number": "2.7.1.150", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,5-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZMK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMK1" } ] }, { "ec_number": "2.7.1.150", "activity": "", "evidence": [ { "id": "A0A8V0ZMK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMK1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZMK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMK1" } ] } ] }, { "uniprot_ac": "A0A8V0ZNP7", "gene_name": "SGK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZNP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNP7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZNP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNP7" } ] } ] }, { "uniprot_ac": "A0A8V0ZPX2", "gene_name": "ALPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZPX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPX2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZPX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPX2" } ] } ] }, { "uniprot_ac": "A0A8V0ZQJ2", "gene_name": "RPS6KB2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZQJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQJ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZQJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQJ2" } ] } ] }, { "uniprot_ac": "A0A8V0ZQT5", "gene_name": "SLC13A3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZQT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQT5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZQT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQT5" } ] } ] }, { "uniprot_ac": "A0A8V0ZRX1", "gene_name": "SETD6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZRX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRX1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZRX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRX1" } ] }, { "ec_number": "2.1.1.-", "activity": "", "evidence": [ { "id": "A0A8V0ZRX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRX1" } ] } ] }, { "uniprot_ac": "A0A8V0ZSB4", "gene_name": "SIK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZSB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSB4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZSB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSB4" } ] } ] }, { "uniprot_ac": "A0A8V0ZSP4", "gene_name": "PKN2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZSP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSP4" } ] }, { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZSP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSP4" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V0ZSP4", "database": 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} ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZUC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUC6" } ] } ] }, { "uniprot_ac": "A0A8V0ZUL0", "gene_name": "PASK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZUL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUL0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZUL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUL0" } ] } ] }, { "uniprot_ac": "A0A8V0ZUU8", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZUU8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUU8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": 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"uniprot_ac": "A0A8V0ZYU6", "gene_name": "TNNI3K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZYU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZYU6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZYU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZYU6" } ] } ] }, { "uniprot_ac": "A0A8V0ZZE4", "gene_name": "OBSCN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZZE4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZE4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZZE4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZE4" } ] } ] }, { "uniprot_ac": "A0A8V0ZZK5", "gene_name": "STK38", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZZK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZK5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZZK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZK5" } ] } ] }, { "uniprot_ac": "A0A8V0ZZV3", "gene_name": "MYO3B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZZV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZV3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZZV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZV3" } ] } ] }, { "uniprot_ac": "A0A8V1A069", "gene_name": "TESK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A069", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A069" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V1A069", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A069" } ] } ] }, { "uniprot_ac": "A0A8V1A0W4", "gene_name": "ULK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A0W4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0W4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A0W4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0W4" } ] } ] }, { "uniprot_ac": "A0A8V1A0Y8", "gene_name": "MAST2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A0Y8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0Y8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A0Y8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0Y8" } ] } ] }, { "uniprot_ac": "A0A8V1A1P3", "gene_name": "SRPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A1P3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1P3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A1P3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1P3" } ] } ] }, { "uniprot_ac": "A0A8V1A1Y7", "gene_name": "CDK2", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A1Y7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1Y7" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V1A1Y7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1Y7" } ] } ] }, { "uniprot_ac": "A0A8V1A2T9", "gene_name": "MAP3K14", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A2T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2T9" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V1A2T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2T9" } ] } ] }, { "uniprot_ac": "A0A8V1A3T8", "gene_name": "MAST3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A3T8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3T8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A3T8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3T8" } ] } ] }, { "uniprot_ac": "A0A8V1A4A1", "gene_name": "CAMKK2", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4A1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4A1" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V1A4A1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4A1" } ] } ] }, { "uniprot_ac": "A0A8V1A4J8", "gene_name": "MAPKAPK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4J8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4J8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A4J8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4J8" } ] } ] }, { "uniprot_ac": "A0A8V1A4Q4", "gene_name": "MAPK3", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4Q4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4Q4" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V1A4Q4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4Q4" } ] } ] }, { "uniprot_ac": "A0A8V1A4V7", "gene_name": "HIPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4V7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4V7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A4V7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4V7" } ] } ] }, { "uniprot_ac": "A0A8V1A513", "gene_name": "DAPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A513", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A513" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A513", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A513" } ] } ] }, { "uniprot_ac": "A0A8V1A675", "gene_name": "CSNK1G2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A675", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A675" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A675", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A675" } ] } ] }, { "uniprot_ac": "A0A8V1A7E0", "gene_name": "DYRK3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7E0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E0" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V1A7E0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E0" } ] } ] }, { "uniprot_ac": "A0A8V1A7E9", "gene_name": "SIK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7E9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A7E9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E9" } ] } ] }, { "uniprot_ac": "A0A8V1A7M0", "gene_name": "STK39", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7M0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7M0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A7M0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7M0" } ] } ] }, { "uniprot_ac": "A0A8V1A7P9", "gene_name": "DCAF1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A7P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P9" } ] } ] }, { "uniprot_ac": "A0A8V1A9S5", "gene_name": "NUAK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A9S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9S5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A9S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9S5" } ] } ] }, { "uniprot_ac": "A0A8V1ABF3", "gene_name": "PRKAA2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] } ] }, { "uniprot_ac": "A0A8V1ABP4", "gene_name": "DSTYK", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABP4" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V1ABP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABP4" } ] } ] }, { "uniprot_ac": "A0A8V1ABR8", "gene_name": "CAMK4L", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABR8" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V1ABR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABR8" } ] } ] }, { "uniprot_ac": "A0A8V1AC40", "gene_name": "CDK18", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AC40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC40" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V1AC40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC40" } ] } ] }, { "uniprot_ac": "A0A8V1ACB5", "gene_name": "MAPK13", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACB5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V1ACB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACB5" } ] } ] }, { "uniprot_ac": "A0A8V1ACF6", "gene_name": "PIM1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACF6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ACF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACF6" } ] } ] }, { "uniprot_ac": "A0A8V1ACK0", "gene_name": "MAPKAPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACK0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ACK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACK0" } ] } ] }, { "uniprot_ac": "A0A8V1ACW2", "gene_name": "WNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACW2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ACW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACW2" } ] } ] }, { "uniprot_ac": "A0A8V1ADF0", "gene_name": "MAP2K2", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ADF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADF0" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V1ADF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADF0" } ] } ] }, { "uniprot_ac": "A0A8V1ADN9", "gene_name": "NLK", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ADN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADN9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V1ADN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADN9" } ] } ] }, { "uniprot_ac": "A0A8V1ADT4", "gene_name": "MKNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ADT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADT4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ADT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADT4" } ] } ] }, { "uniprot_ac": "A0A8V1AE45", "gene_name": "ERN1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AE45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE45" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AE45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE45" } ] } ] }, { "uniprot_ac": "A0A8V1AEH4", "gene_name": "STK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AEH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEH4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AEH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEH4" } ] } ] }, { "uniprot_ac": "A0A8V1AFS4", "gene_name": "STKLD1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AFS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFS4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AFS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFS4" } ] } ] }, { "uniprot_ac": "A0A8V1AG70", "gene_name": "LOC100857512", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AG70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AG70" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AG70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AG70" } ] } ] }, { "uniprot_ac": "A0A8V1AH12", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AH12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH12" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AH12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH12" } ] } ] }, { "uniprot_ac": "A0A8V1AHA8", "gene_name": "NEK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AHA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHA8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AHA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHA8" } ] } ] }, { "uniprot_ac": "A0A8V1AIY7", "gene_name": "AATK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AIY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIY7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AIY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIY7" } ] } ] }, { "uniprot_ac": "A0A8V1AJA4", "gene_name": "RPS6KB1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AJA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJA4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AJA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJA4" } ] } ] }, { "uniprot_ac": "A0A8V1AKW4", "gene_name": "MAP2K4", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AKW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKW4" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V1AKW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKW4" } ] } ] }, { "uniprot_ac": "A0A8V1AM12", "gene_name": "GSG2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AM12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM12" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AM12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM12" } ] } ] }, { "uniprot_ac": "A0A8V1AMK5", "gene_name": "PRKCA", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AMK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMK5" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V1AMK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMK5" } ] } ] }, { "uniprot_ac": "A0A8V1AMQ2", "gene_name": "CAMKK1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AMQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMQ2" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V1AMQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMQ2" } ] } ] }, { "uniprot_ac": "A0A8V1AP60", "gene_name": "KSR1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AP60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP60" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AP60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP60" } ] } ] }, { "uniprot_ac": "E1BQN6", "gene_name": "PRKCZ", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BQN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQN6" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1BQN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQN6" } ] } ] }, { "uniprot_ac": "E1BQV7", "gene_name": "SLK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BQV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQV7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BQV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQV7" } ] } ] }, { "uniprot_ac": "E1BUG0", "gene_name": "CDK12", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] } ] }, { "uniprot_ac": "E1BW33", "gene_name": "SMG1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BW33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BW33" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BW33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BW33" } ] } ] }, { "uniprot_ac": "E1BWA3", "gene_name": "PRKCI", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BWA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWA3" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1BWA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWA3" } ] } ] }, { "uniprot_ac": "E1BWT0", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BWT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWT0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BWT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWT0" } ] } ] }, { "uniprot_ac": "E1BX69", "gene_name": "EIF2AK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BX69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BX69" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BX69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BX69" } ] } ] }, { "uniprot_ac": "E1BY69", "gene_name": "PIM3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BY69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BY69" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BY69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BY69" } ] } ] }, { "uniprot_ac": "E1BYH2", "gene_name": "TAOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BYH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BYH2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BYH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BYH2" } ] } ] }, { "uniprot_ac": "E1C093", "gene_name": "PIK3CG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.154", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.154", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] } ] }, { "uniprot_ac": "E1C2I2", "gene_name": "MASTL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C2I2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C2I2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C2I2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C2I2" } ] } ] }, { "uniprot_ac": "E1C581", "gene_name": "TBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C581", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C581" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C581", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C581" } ] } ] }, { "uniprot_ac": "E1C6T4", "gene_name": "PRKD3", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C6T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C6T4" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1C6T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C6T4" } ] } ] }, { "uniprot_ac": "E1C764", "gene_name": "BMP2K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C764", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C764" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C764", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C764" } ] } ] }, { "uniprot_ac": "E1C848", "gene_name": "MAP3K8", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C848", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C848" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1C848", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C848" } ] } ] }, { "uniprot_ac": "F1NA68", "gene_name": "CDK3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NA68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NA68" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1NA68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NA68" } ] } ] }, { "uniprot_ac": "F1NB57", "gene_name": "PLK2", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NB57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NB57" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "F1NB57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NB57" } ] } ] }, { "uniprot_ac": "F1NBT0", "gene_name": "STK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NBT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NBT0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1NBT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NBT0" } ] } ] }, { "uniprot_ac": "F1NCX7", "gene_name": "PLK1", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NCX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCX7" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "F1NCX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCX7" } ] } ] }, { "uniprot_ac": "F1NCY7", "gene_name": "MAPKAPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NCY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCY7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1NCY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCY7" } ] } ] }, { "uniprot_ac": "F1NJH1", "gene_name": "PRKCH", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NJH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NJH1" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1NJH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NJH1" } ] } ] }, { "uniprot_ac": "F1NKW3", "gene_name": "MAP3K15", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NKW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NKW3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1NKW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NKW3" } ] } ] }, { "uniprot_ac": "F1NLR7", "gene_name": "CLK3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NLR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NLR7" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "F1NLR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NLR7" } ] } ] }, { "uniprot_ac": "F1NUX4", "gene_name": "MTOR", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NUX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NUX4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1NUX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NUX4" } ] } ] }, { "uniprot_ac": "F1NVF2", "gene_name": "MAP2K6", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NVF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NVF2" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "F1NVF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NVF2" } ] } ] }, { "uniprot_ac": "F1P011", "gene_name": "CAMK2A", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1P011", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P011" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "F1P011", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P011" } ] } ] }, { "uniprot_ac": "F1P356", "gene_name": "NUAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1P356", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P356" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1P356", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P356" } ] } ] }, { "uniprot_ac": "F1P4G3", "gene_name": "HIPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1P4G3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P4G3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1P4G3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P4G3" } ] } ] }, { "uniprot_ac": "P05625", "gene_name": "RAF1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P05625", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05625" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P05625", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05625" } ] } ] }, { "uniprot_ac": "P10741", "gene_name": "MOS", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P10741", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P10741" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P10741", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P10741" } ] } ] }, { "uniprot_ac": "P13863", "gene_name": "CDK1", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P13863", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13863" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "P13863", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13863" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "P13863", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13863" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "P13863", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13863" } ] } ] }, { "uniprot_ac": "P18652", "gene_name": "RPS6KA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P18652", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P18652" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P18652", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P18652" } ] } ] }, { "uniprot_ac": "P21868", "gene_name": "CSNK2A1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P21868", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P21868" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P21868", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P21868" } ] } ] }, { "uniprot_ac": "P21869", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P21869", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P21869" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P21869", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P21869" } ] } ] }, { "uniprot_ac": "P53666", "gene_name": "LIMK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P53666", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P53666" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P53666", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P53666" } ] } ] }, { "uniprot_ac": "P67962", "gene_name": "CSNK1A1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P67962", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P67962" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P67962", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P67962" } ] } ] }, { "uniprot_ac": "P79996", "gene_name": "MAPK9", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P79996", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P79996" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "P79996", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P79996" } ] } ] }, { "uniprot_ac": "Q04982", "gene_name": "BRAF", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q04982", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q04982" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q04982", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q04982" } ] } ] }, { "uniprot_ac": "Q0GGW5", "gene_name": "STK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q0GGW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0GGW5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q0GGW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0GGW5" } ] } ] }, { "uniprot_ac": "Q5F3L1", "gene_name": "RPS6KA5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5F3L1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F3L1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q5F3L1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F3L1" } ] } ] }, { "uniprot_ac": "Q5F3W3", "gene_name": "MAPK6", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5F3W3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F3W3" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "Q5F3W3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F3W3" } ] } ] }, { "uniprot_ac": "Q5ZIU3", "gene_name": "DYRK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5ZIU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZIU3" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "Q5ZIU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZIU3" } ] } ] }, { "uniprot_ac": "Q5ZJH6", "gene_name": "ULK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5ZJH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJH6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q5ZJH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJH6" } ] } ] }, { "uniprot_ac": "Q5ZJK4", "gene_name": "STK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5ZJK4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJK4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q5ZJK4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJK4" } ] } ] }, { "uniprot_ac": "Q5ZJS0", "gene_name": "CSNK1G1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5ZJS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJS0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q5ZJS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJS0" } ] } ] }, { "uniprot_ac": "Q5ZKI0", "gene_name": "CAMK2D", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5ZKI0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKI0" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "Q5ZKI0", "database": "UniProtKB", "url": 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"activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5ZLL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZLL1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q5ZLL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZLL1" } ] } ] }, { "uniprot_ac": "Q6U1I9", "gene_name": "SGK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q6U1I9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6U1I9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q6U1I9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6U1I9" } ] } ] }, { "uniprot_ac": "Q6XUX0", "gene_name": "DSTYK", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q6XUX0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6XUX0" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "Q6XUX0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6XUX0" } ] } ] }, { "uniprot_ac": "Q7T0B1", "gene_name": "STK40", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q7T0B1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q7T0B1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q7T0B1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q7T0B1" } ] } ] }, { "uniprot_ac": "Q8AYC9", "gene_name": "CHEK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q8AYC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8AYC9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8AYC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8AYC9" } ] } ] }, { "uniprot_ac": "Q8QFP8", "gene_name": "LIMK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q8QFP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8QFP8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8QFP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8QFP8" } ] } ] }, { "uniprot_ac": "Q8QGX4", "gene_name": "PRKDC", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q8QGX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8QGX4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8QGX4", "database": "UniProtKB", "url": 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COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015133023", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015133023" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMC5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMC5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "DAB2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMC5", "locus": { "chromosome": "Z", "start_pos": 12897413, "end_pos": 12921411, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013409", "url": "https://www.ensembl.org/id/ENSGALG00010013409" } ] } } ], "crossref": [ { "id": "A0A8V0YMC5", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YMC5", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd01215", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01215", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "427449", "url": "https://www.ncbi.nlm.nih.gov/gene/427449", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006020", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006020", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048559", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048559", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048561", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048561", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:427449", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427449", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "FMSHEPI", "url": "https://omabrowser.org/oma/group/FMSHEPI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YMC5", "url": "https://www.orthodb.org/?gene=A0A8V0YMC5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YSA7", "url": "https://www.orthodb.org/?gene=A0A8V0YSA7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47695", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47695", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47695:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47695:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF21792", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21792", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-190873", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-190873", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-196025", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-196025", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_015133023", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015133023", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YMC5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMC5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YMC5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMC5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YSA7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSA7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YSA7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSA7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSTEAETTSTVNSQPEHQAPPKAQTSKKEKKKGPEKTDESLLARFKGDGVRYKAKLIGIDDVPEARGDKMSQDSMMKLKGMAVAARSQGQHKQRIWVNISLSGIKIIDEKTGVIEHEHPVTKISFIARDVTDNRAFGYICGGEGQHQFFAIKTAQQAEPLVVDLKDLFQLIYNMKKKEEEEDKKKSEEANKTQNGSEALAAGQADKLKLGVDQMDLFGDMSTPPDLSSPSEAKEILLVDLNSEIETKQTFTKEDLFLNGITPSLPQPKPRPPFLPESSFSTNLNFFPTPNPDPFSDDPFAQPDQSAPPSFDSLKSADQKKENLSTLTSVGNGASNGDVDYFGKQFDQISNRVGKREALTSQWPFDSKPPTARTPNGVPEREQNGFLKVPSNLFVEDPSKGVILQNGVKLDSESNIQLLSHESITISPPPQSNKPGRGRRSVKTASNDLFSSDFFAPTTENVGLNSSVQTGLVQTNRLDLFKTNPTTAPPLAGLGGMPSPWSTEIPAFTQATSVFPGSMMRTQSPGFTQQLTFGTQAVPSWSQPGSFGPTVSQSSGLWAQPAQVPPAPWVQPSSAVNPFQSSVFAPSTLPAQTQSVLPPVSTTSPPQPPPRTAPQKELSKKESDAFIALDPLGDREMKDVKEMFKDFQLTKPPAVPARRGEQQSLSEPLKPVPRQSALPIDGLFESQPKPDLFSVSSESQKQPSCPFGGHSGNPFV", "length": 715, "header": "tr|A0A8V0YMC5-1|A0A8V0YMC5_CHICK Isoform 1 of DAB adaptor protein 2 OS=Gallus gallus OX=9031 GN=DAB2 PE=1 SV=1 CANONICAL=A0A8V0YMC5-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YMC5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMC5/entry#A0A8V0YMC5-1", "sequence": { "sequence": "MSTEAETTSTVNSQPEHQAPPKAQTSKKEKKKGPEKTDESLLARFKGDGVRYKAKLIGIDDVPEARGDKMSQDSMMKLKGMAVAARSQGQHKQRIWVNISLSGIKIIDEKTGVIEHEHPVTKISFIARDVTDNRAFGYICGGEGQHQFFAIKTAQQAEPLVVDLKDLFQLIYNMKKKEEEEDKKKSEEANKTQNGSEALAAGQADKLKLGVDQMDLFGDMSTPPDLSSPSEAKEILLVDLNSEIETKQTFTKEDLFLNGITPSLPQPKPRPPFLPESSFSTNLNFFPTPNPDPFSDDPFAQPDQSAPPSFDSLKSADQKKENLSTLTSVGNGASNGDVDYFGKQFDQISNRVGKREALTSQWPFDSKPPTARTPNGVPEREQNGFLKVPSNLFVEDPSKGVILQNGVKLDSESNIQLLSHESITISPPPQSNKPGRGRRSVKTASNDLFSSDFFAPTTENVGLNSSVQTGLVQTNRLDLFKTNPTTAPPLAGLGGMPSPWSTEIPAFTQATSVFPGSMMRTQSPGFTQQLTFGTQAVPSWSQPGSFGPTVSQSSGLWAQPAQVPPAPWVQPSSAVNPFQSSVFAPSTLPAQTQSVLPPVSTTSPPQPPPRTAPQKELSKKESDAFIALDPLGDREMKDVKEMFKDFQLTKPPAVPARRGEQQSLSEPLKPVPRQSALPIDGLFESQPKPDLFSVSSESQKQPSCPFGGHSGNPFV", "length": 715, "header": "tr|A0A8V0YMC5-1|A0A8V0YMC5_CHICK Isoform 1 of DAB adaptor protein 2 OS=Gallus gallus OX=9031 GN=DAB2 PE=1 SV=1 CANONICAL=A0A8V0YMC5-1" }, "locus": { "chromosome": "Z", "start_pos": 12909424, "end_pos": 12899656, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032286.1", "url": "https://www.ensembl.org/id/ENSGALT00010032286.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019076.1", "url": "https://www.ensembl.org/id/ENSGALP00010019076.1" } ] } }, { "isoform_ac": "A0A8V0YSA7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMC5/entry#A0A8V0YSA7-1", "sequence": { "sequence": "MSTEAETTSTVNSQPEHQAPPKAQTSKKEKKKGPEKTDESLLARFKGDGVRYKAKLIGIDDVPEARGDKMSQDSMMKLKGMAVAARSQGQHKQRIWVNISLSGIKIIDEKTGVIEHEHPVTKISFIARDVTDNRAFGYICGGEGQHQFFAIKTAQQAEPLVVDLKDLFQLIYNMKKKEEEEDKKKNGSEALAAGQADKLKLGVDQMDLFGDMSTPPDLSSPSEAKEILLVDLNSEIETKQTFTKEDLFLNGITPSLPQPKPRPPFLPESSFSTNLNFFPTPNPDPFSDDPFAQPDQSAPPSFDSLKSADQKKENLSTLTSVGNGASNGDVDYFGKQFDQISNRVGKREALTSQWPFDSKPPTARTPNGVPEREQNGFLKVPSNLFVEDPSKGVILQNGVKLDSESNIQLLSHESITISPPPQSNKPGRGRRSVKTASNDLFSSDFFAPTTENVGLNSSVQTGLVQTNRLDLFKTNPTTAPPLAGLGGMPSPWSTEIPAFTQATSVFPGSMMRTQSPGFTQQLTFGTQAVPSWSQPGSFGPTVSQSSGLWAQPAQVPPAPWVQPSSAVNPFQSSVFAPSTLPAQTQSVLPPVSTTSPPQPPPRTAPQKELSKKESDAFIALDPLGDREMKDVKEMFKDFQLTKPPAVPARRGEQQSLSEPLKPVPRQSALPIDGLFESQPKPDLFSVSSESQKQPSCPFGGHSGNPFV", "length": 707, "header": "tr|A0A8V0YSA7-1|A0A8V0YSA7_CHICK Computationally mapped isoform of DAB adaptor protein 2 OS=Gallus gallus OX=9031 GN=DAB2 PE=1 SV=1 CANONICAL=A0A8V0YMC5-1" }, "locus": { "chromosome": "Z", "start_pos": 12909424, "end_pos": 12899656, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032289.1", "url": "https://www.ensembl.org/id/ENSGALT00010032289.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019079.1", "url": "https://www.ensembl.org/id/ENSGALP00010019079.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 549, "start_aa": "Thr", "end_pos": 549, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr549", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:427449", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427449", "resource": "KEGG Pathway" }, { "id": "R-GGA-190873", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-190873", "resource": "Reactome", "description": "Gap junction degradation" }, { "id": "R-GGA-196025", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-196025", "resource": "Reactome", "description": "Formation of annular gap junctions" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3Q1LSX5-1", "protein_name": "DAB adaptor protein 2", "gene_name": "DAB2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSNEVETSATNGQPDQQAAPKAPSKKEKKKGTEKTDEYLLARFKGDGVKYKAKLIGIDDVPDARGDKMSQDSMMKLKGMAAAARSQGQHKQRIWVNISLSGIKIIDEKTGVIEHEHPVNKISFIARDVTDNRAFGYVCGGEGQHQFFAIKTGQQAEPLVIDLKDLFQVIYNTKKKEEEKKKMEEANKTVENGSDALMNLDDPPCKLKLESKDILLVDLNSEIDTNQNSLQENLFLTNGITSCSLPRPKPQASFLPENAFSANLNFFPTPNPDPFRDDPFAQPDQSTPSSSDSLKSPDQKKENLSSSSTPLSNGPLNGDVDYFGQQFDQISNRTGKQEAQAGPWPLSSTQTQPAVRTHNEVSEREQNGFHIKSSPNPFVGSPPKGLPVPNGVKQDLESSVQSSPHDSIAIIPPPQSTKPGRGRRTAKSPAKDLLAADIFAPPISEPPGQSPGQPATLQTNPLDLFKTSAPAPLGPLPGLGGVPVLSAQAAPWSPAPLVFSQSPSMVPGAMMAGQPSGFSQPIVFTTSPSVPGWNQPSSFAVSVSSPPPVAWGTSASITPNTWSANSPLGNPFQSNVFPAPAVSTPPPSMLSSLLATPPQPPPRTGPPKDVPSDAFIALDPLGDREVKEVKEMFKDFQLRQPPTVPARKGEQNSSGTSSAFSNYFNSKVGIPQENADHDDLDANQLLRKINDLPKPAPRHSAPPVTKSADNAFENPFSKDSFHSSPASMASLQPTSSDIYRDPFGNPFA", "length": 747 }, "evidence": [ { "id": "A0A8V0YMC5", "url": "https://omabrowser.org/oma/group/A0A8V0YMC5/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A8C2MQT1-1", "protein_name": "Disabled homolog 2 isoform X1", "gene_name": "Dab2", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSNEVETSTTNGQPDQQAAPKVPSKKEKKKGSEKTDEYLLARFKGDGVKYKAKLIGIDDVPDARGDKMSQDSMMKLKGMAAAGRSQGQHKQRIWVNISLSGIKIIDEKTGVIEHEHPVNKISFIARDVTDNRAFGYVCGGEGQHQFFAIKTGQQAEPLVVDLKDLFQVIYNVKKKEEEKKKVEEASKAEENGSEALMNLDDQANKLKLGVDQMDLFGDMSTPPDLNSPTESKDILLVDLNSEIDTNQNSLRENPFLTNGVTSCSLPRPKPQASFLPENAFSANLNFFPTPNPDPFRDDPFAQPDQSAPSSFDSLTSSDQKKANLSSLSTPLSKGPLNGDTDYFGQQFDQISNRTGKQEAQAGPWPYPSSQTQQAVRTQNGVSEREQNGFHNKSSPNPFVESPPPKGLSVPNGVKPDLESSVQSSAHDSIAIIPPPQSTKPGRGRRTAKSSANDLLASDIFASEPPGQTSPTGQPAAPQTNPLDLFKTSAPAPMGPLAGLGGVSVTPPQAGPWTPVVFSPSTSVVPGAIISGQPSGFGQPIVFSATPAVQVWNQPSSFAAPASPPPPAVWCSPAPVAPNAWSSTSPLGNPFQSTTFPPPAMPSQATPMLSSVLATPPQPPPRNGPLKDIPSDAFTGLDPLGDKEVKEVKEMFKDFQLRQPPVVPSRKGETPPTGTSSAFSSYFNSKVGIPQEHVDHDDYDANQLLSKINEPPKPVPRQGLLSSTKSADNSLENPFSKGCFSSPQPSVASQPASSDAHRSPFGNPFA", "length": 765 }, "evidence": [ { "id": "A0A8V0YMC5", "url": "https://omabrowser.org/oma/group/A0A8V0YMC5/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "O88797-1", "protein_name": "Disabled homolog 2", "gene_name": "Dab2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSNEVETSTTNGQPDQQAAPKAPSKKEKKKGSEKTDEYLLARFKGDGVKYKAKLIGIDDVPDARGDKMSQDSMMKLKGMAAAGRSQGQHKQRIWVNISLSGIKIIDEKTGVIEHEHPVNKISFIARDVTDNRAFGYVCGGEGQHQFFAIKTGQQAEPLVVDLKDLFQVIYNVKKKEEEKKKVEEANKAEENGSEALMTLDDQANKLKLGVDQMDLFGDMSTPPDLNNPTESRDILLVDLNSEIDTNQNSLRENPFLTNGVTSCSLPRPKPQASFLPESAFSANLNFFPTPNPDPFRDDPFAQPDQSAPSSFHSLTSADQKKANPGSLSTPQSKGPLNGDTDYFGQQFDQISNRTGKQEAQGGPWPYPSSQTQQAVRTQNGVSEKEQNGFHIKSSPNPFVGSPPKGLSVPNGVKQDLESSVQSSAHDSIAIIPPPQSTKPGRGRRTAKSSANDLLASDIFASEPPGQMSPTGQPAVPQANFMDLFKTSAPAPMGSGPLVGLGTVPVTPPQAGPWTPVVFTPSTTVVPGAIISGQPSGFGQPLVFGTTPAVQVWNQPSSFATAASPPPPAVWCPTTSVAPNTWSSTSPLGNPFQSSNIFPPSTISTQSFPQPMMSSVLVTPPQPPPRNGPLKDTLSDAFTGLDPLGDKEVKEVKEMFKDFQLRQPPLVPSRKGETPSSGTSSAFSSYFNNKVGIPQEHVDHDDFDANQLLNKINEPPKPAPRQGVLSGTKSADNSLENPFSKGFSSTNPSVVSQPASSDAHRSPFGNPFA", "length": 768 }, "evidence": [ { "id": "A0A8V0YMC5", "url": "https://omabrowser.org/oma/group/A0A8V0YMC5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P98078-1", "protein_name": "Disabled homolog 2", "gene_name": "Dab2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSNEVETSTTNGQPDQQAAPKAPSKKEKKKGSEKTDEYLLARFKGDGVKYKAKLIGIDDVPDARGDKMSQDSMMKLKGMAAAGRSQGQHKQRIWVNISLSGIKIIDEKTGVIEHEHPVNKISFIARDVTDNRAFGYVCGGEGQHQFFAIKTGQQAEPLVVDLKDLFQVIYNVKKKEEDKKKVEEANKAEENGSEALMTLDDQANKLKLGVDQMDLFGDMSTPPDLNSPTESKDILLVDLNSEIDTNQNSLRENPFLTNGVTSCSLPRPKPQASFLPENAFSANLNFFPTPNPDPFRDDPFAQPDQSAPSSFDSLTSPDQKKASLSSSSTPQSKGPLNGDTDYFGQQFDQLSNRTGKPEAQGGPWPYPSSQTQQAVRTQNGVSEREQNGFHIKSSPNPFVGSPPKGLSVPNGVKQDLESSVQSSAHDSIAIIPPPQSTKPGRGRRTAKSSANDLLASDIFASEPPGQMSPTGQPAVPQSNFLDLFKGNAPAPVGPLVGLGTVPVTPPQAGPWTPVVYSPSTTVVPGAIISGQPPSFRQPLVFGTTPAVQVWNQSPSFATPASPPPPTVWCPTTSVAPNAWSSTSPLGNPFQSNNIFPPPTMSTQSSPQPMMSSVLATPPQPPPRNGPLKDIPSDAFTGLDPLGDKEVKEVKEMFKDFQLRQPPLVPSRKGETPPSGTSSAFSSYFNNKVGIPQEHVDHDDFDANQLLNKINEPPKPAPRQGVLLGTKSADNSLENPFSKGFSSSNPSVVSQPASSDPHRSPFGNPFA", "length": 766 }, "evidence": [ { "id": "A0A8V0YMC5", "url": "https://omabrowser.org/oma/group/A0A8V0YMC5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P98082-1", "protein_name": "Disabled homolog 2", "gene_name": "DAB2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSNEVETSATNGQPDQQAAPKAPSKKEKKKGPEKTDEYLLARFKGDGVKYKAKLIGIDDVPDARGDKMSQDSMMKLKGMAAAGRSQGQHKQRIWVNISLSGIKIIDEKTGVIEHEHPVNKISFIARDVTDNRAFGYVCGGEGQHQFFAIKTGQQAEPLVVDLKDLFQVIYNVKKKEEEKKKIEEASKAVENGSEALMILDDQTNKLKSGVDQMDLFGDMSTPPDLNSPTESKDILLVDLNSEIDTNQNSLRENPFLTNGITSCSLPRPTPQASFLPENAFSANLNFFPTPNPDPFRDDPFTQPDQSTPSSFDSLKSPDQKKENSSSSSTPLSNGPLNGDVDYFGQQFDQISNRTGKQEAQAGPWPFSSSQTQPAVRTQNGVSEREQNGFSVKSSPNPFVGSPPKGLSIQNGVKQDLESSVQSSPHDSIAIIPPPQSTKPGRGRRTAKSSANDLLASDIFAPPVSEPSGQASPTGQPTALQPNPLDLFKTSAPAPVGPLVGLGGVTVTLPQAGPWNTASLVFNQSPSMAPGAMMGGQPSGFSQPVIFGTSPAVSGWNQPSPFAASTPPPVPVVWGPSASVAPNAWSTTSPLGNPFQSNIFPAPAVSTQPPSMHSSLLVTPPQPPPRAGPPKDISSDAFTALDPLGDKEIKDVKEMFKDFQLRQPPAVPARKGEQTSSGTLSAFASYFNSKVGIPQENADHDDFDANQLLNKINEPPKPAPRQVSLPVTKSTDNAFENPFFKDSFGSSQASVASSQPVSSEMYRDPFGNPFA", "length": 770 }, "evidence": [ { "id": "A0A8V0YMC5", "url": "https://omabrowser.org/oma/group/A0A8V0YMC5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 18, "go_terms": [ { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMC5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMC5" } ], "pmid": "" }, { "name": "positive regulation of cell migration", "id": "GO:0030335", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030335", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMC5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMC5" } ], "pmid": "" }, { "name": "negative regulation of apoptotic process", "id": "GO:0043066", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043066", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMC5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMC5" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMC5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMC5" } ], "pmid": "" }, { "name": "negative regulation of canonical Wnt signaling pathway", "id": "GO:0090090", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090090", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMC5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMC5" } ], "pmid": "" }, { "name": "transforming growth factor beta receptor signaling pathway", "id": "GO:0007179", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007179", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMC5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMC5" } ], "pmid": "" }, { "name": "positive regulation of Wnt signaling pathway, planar cell polarity pathway", "id": "GO:2000096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000096", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMC5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMC5" } ], "pmid": "" }, { "name": "receptor-mediated endocytosis", "id": "GO:0006898", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006898", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMC5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMC5" } ], "pmid": "" }, { "name": "negative regulation of protein localization to plasma membrane", "id": "GO:1903077", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903077", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMC5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMC5" } ], "pmid": "" }, { "name": "positive regulation of proteasomal ubiquitin-dependent protein catabolic process", "id": "GO:0032436", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032436", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMC5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMC5" } ], "pmid": "" }, { "name": "positive regulation of epithelial to mesenchymal transition", "id": "GO:0010718", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010718", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMC5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMC5" } ], "pmid": "" }, { "name": "positive regulation of endocytosis", "id": "GO:0045807", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045807", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMC5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMC5" } ], "pmid": "" }, { "name": "positive regulation of SMAD protein signal transduction", "id": "GO:0060391", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060391", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMC5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMC5" } ], "pmid": "" }, { "name": "leading edge cell differentiation", "id": "GO:0035026", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035026", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMC5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMC5" } ], "pmid": "" }, { "name": "negative regulation of androgen receptor signaling pathway", "id": "GO:0060766", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060766", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMC5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMC5" } ], "pmid": "" }, { "name": "positive regulation of clathrin-dependent endocytosis", "id": "GO:2000370", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000370", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMC5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMC5" } ], "pmid": "" }, { "name": "positive regulation of early endosome to late endosome transport", "id": "GO:2000643", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000643", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMC5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMC5" } ], "pmid": "" }, { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMC5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMC5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMC5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMC5" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMC5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMC5" } ], "pmid": "" }, { "name": "clathrin-coated pit", "id": "GO:0005905", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005905", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMC5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMC5" } ], "pmid": "" }, { "name": "clathrin-coated vesicle", "id": "GO:0030136", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030136", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMC5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMC5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "SMAD binding", "id": "GO:0046332", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046332", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMC5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMC5" } ], "pmid": "" }, { "name": "clathrin adaptor activity", "id": "GO:0035615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035615", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMC5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMC5" } ], "pmid": "" }, { "name": "cargo receptor activity", "id": "GO:0038024", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038024", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMC5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMC5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 190, "end_pos": 192, "annotation": "n_glycosylation_sequon" }, { "start_pos": 194, "end_pos": 196, "annotation": "n_glycosylation_sequon" }, { "start_pos": 322, "end_pos": 324, "annotation": "n_glycosylation_sequon" }, { "start_pos": 464, "end_pos": 466, "annotation": "n_glycosylation_sequon" }, { "start_pos": 98, "end_pos": 100, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YMC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMC5" }, { "id": "PS01179", "database": "PROSITE", "url": "https://prosite.expasy.org/PS01179" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PID", "eco_id": "ECO_0000259", "start_pos": 47, "end_pos": 180, "start_aa": "Gly", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 549 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 190, "end_pos": 192 }, { "start_pos": 194, "end_pos": 196 }, { "start_pos": 322, "end_pos": 324 }, { "start_pos": 464, "end_pos": 466 }, { "start_pos": 98, "end_pos": 100 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { 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"publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YMC8-1", "uniprot_ac": "A0A8V0YMC8", "uniprot_id": "A0A8V0YMC8_CHICK", "mass": { "chemical_mass": 36983.0, "monoisotopic_mass": 36983.0 }, "refseq": { "ac": "XP_004943908", "name": "apoptosis-enhancing nuclease", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004943908" }, "gene_names": [ { "name": "AEN", "type": "recommended", "evidence": [ { "id": "A0A8V0YMC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMC8" } ] }, { "name": "AEN", "type": "synonym", "evidence": [ { "id": "XP_004943908", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004943908" } ] } ], "protein_names": [ { "name": "Apoptosis enhancing nuclease", "type": "synonym", "evidence": [ { "id": "A0A8V0YMC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMC8/entry#names_and_taxonomy" } ] }, { "name": "apoptosis-enhancing nuclease", "type": "synonym", "evidence": [ { "id": "XP_004943908", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004943908" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052541.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_004943908.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004943908", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004943908" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMC8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMC8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "AEN", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMC8", "locus": {} } ], "crossref": [ { "id": "A0A8V0YMC8", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YMC8", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd06149", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06149", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "415496", "url": "https://www.ncbi.nlm.nih.gov/gene/415496", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR012337", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012337", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013520", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013520", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036397", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036397", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037433", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037433", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047021", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047021", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:415496", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:415496", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "TDTEQYM", "url": 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[ "Protein" ] }, { "id": "A0A8V0YMC8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMC8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSPGKGQMTPLLLPKASAPTPKRTHGPAGPPSPRMTPQGPGSKKKSRRHQRFMERRALLERRGLLRPRRRLGTQGPPGGLSSVTPRGWKVSKLGLSVSPSASPNGIVGRCCGTSVGNAVTGVQLCPPRPNKYVAIDCEMVGTGPRGRQSELARCSIVSYDGDVIYDKYVLPLLPVVDFRTRWSGITKRHMESAIPFRAAQEEILKILKDRIVVGHAIHNDFQALKYFHPKEKTRDTSRIPLLNQRAGLPPGANASLKSLARHLLQKKIQVGCKGHSSVEDARTAMELYRLVEVPWEAELARSQPPRPPSPTDPITDSHQYMDDQYWPQDLMVGTL", "length": 335, "header": "tr|A0A8V0YMC8-1|A0A8V0YMC8_CHICK Isoform 1 of Apoptosis enhancing nuclease OS=Gallus gallus OX=9031 GN=AEN PE=4 SV=1 CANONICAL=A0A8V0YMC8-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YMC8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMC8/entry#A0A8V0YMC8-1", "sequence": { "sequence": "MSPGKGQMTPLLLPKASAPTPKRTHGPAGPPSPRMTPQGPGSKKKSRRHQRFMERRALLERRGLLRPRRRLGTQGPPGGLSSVTPRGWKVSKLGLSVSPSASPNGIVGRCCGTSVGNAVTGVQLCPPRPNKYVAIDCEMVGTGPRGRQSELARCSIVSYDGDVIYDKYVLPLLPVVDFRTRWSGITKRHMESAIPFRAAQEEILKILKDRIVVGHAIHNDFQALKYFHPKEKTRDTSRIPLLNQRAGLPPGANASLKSLARHLLQKKIQVGCKGHSSVEDARTAMELYRLVEVPWEAELARSQPPRPPSPTDPITDSHQYMDDQYWPQDLMVGTL", "length": 335, "header": "tr|A0A8V0YMC8-1|A0A8V0YMC8_CHICK Isoform 1 of Apoptosis enhancing nuclease OS=Gallus gallus OX=9031 GN=AEN PE=4 SV=1 CANONICAL=A0A8V0YMC8-1" }, "locus": { "chromosome": "10", "start_pos": 13147032, "end_pos": 13145291, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010038318.1", "url": "https://www.ensembl.org/id/ENSGALT00010038318.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010022133.1", "url": "https://www.ensembl.org/id/ENSGALP00010022133.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 311, "start_aa": "Thr", "end_pos": 311, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr311", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:415496", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:415496", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A4X1WCN6-1", "protein_name": "Apoptosis enhancing nuclease", "gene_name": "AEN", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MVPREAPESTQCLCPSLGSSNAKDVLRRKHKRKSRQHQRFMARKALLQEQGLLSAPPEPGSSPLPMLLDAPPGTEASSSVRQRPKAESGGAPCSRKPTPRESAGPLPSKCVAIDCEMVGTGPRGRVSELARCSVVSYYGDVLYDKYIRPEMPIVDYRTRWSGITRQHMRKAIPFQVAQKEILKLLKGKVVVGHALHNDFQALKYVHPRGQTRDTTYVPNLLSQPGLHTRTRVSLKDLALQLLHKKIQVGQHGHSSVEDAVTAMELYRLVEVQWEQQEASSPRSHPEDREPDSSTDMEQYMEDQYWPEDLAPGTSSGSGEAQGRRE", "length": 325 }, "evidence": [ { "id": "A0A8V0YMC8", "url": "https://omabrowser.org/oma/group/A0A8V0YMC8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "B2GUW6-1", "protein_name": "Apoptosis-enhancing nuclease", "gene_name": "Aen", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVPREVPESSLTSLKTKDVARRRHKRRSRQHQRFMARKALLQEQESLSMVPGPGLCPLPSPTQTPAGTEASGNRKQRTKARSGSKGLCSKRPVPREAPSSGPSKYVAIDCEMVGTGPQGRVSELARCSVVSYSGDVLYDKYIRPEMPIVDYRTRWSGITRQHMHKAIPFQVAQKEILKLLKGKVVVGHALHNDFQALKYVHPGSQIRDTTYVPNLLSQPSSLTRARVSLKDLALNLLHKKIQVGHHGHSSVEDAMTAMELYQLVEVQWEQQVASTAKAHPEDRGPDSSTDVEQYMDDQYWPEDLAQSTRGDTREAQDRQEGEEGQGARSAPP", "length": 332 }, "evidence": [ { "id": "A0A8V0YMC8", "url": "https://omabrowser.org/oma/group/A0A8V0YMC8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3ICD7-1", "protein_name": "Apoptosis-enhancing nuclease", "gene_name": "Aen", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MVLGEVPESTQCPSLTSLNTKDVVRKRHKRRSRQHQRFMARKALLQGNMAPGPESCPLSSPSQTPADTQASGSRRQRSKATPGGGGPCSKRPVTREAQRPGPSKCVAIDCEMVGTGPRGRVSELARCSVVSYNGDVLYDKYIRPEMPIVDYRTRWSGITRQHMLKAIPFQVAQKEILKLLKGKVVVGHALHNDFQALKYVHPRSQTRDTTYVPNLLSQPSFHTRARVSLKDLALHLLHKKIQVGHQGHSSVEDAMTAMELYQLVEVQWEQQEANNAKALPEDRGSDSSTDMEQYMEDQYWPDELAQSTSGEIREAQEGRE", "length": 320 }, "evidence": [ { "id": "A0A8V0YMC8", "url": "https://omabrowser.org/oma/group/A0A8V0YMC8/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q8WTP8-1", "protein_name": "Apoptosis-enhancing nuclease", "gene_name": "AEN", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVPREAPESAQCLCPSLTIPNAKDVLRKRHKRRSRQHQRFMARKALLQEQGLLSMPPEPGSSPLPTPFGAATATEAASSGKQCLRAGSGSAPCSRRPAPGKASGPLPSKCVAIDCEMVGTGPRGRVSELARCSIVSYHGNVLYDKYIRPEMPIADYRTRWSGITRQHMRKAVPFQVAQKEILKLLKGKVVVGHALHNDFQALKYVHPRSQTRDTTYVPNFLSEPGLHTRARVSLKDLALQLLHKKIQVGQHGHSSVEDATTAMELYRLVEVQWEQQEARSLWTCPEDREPDSSTDMEQYMEDQYWPDDLAHGSRGGAREAQDRRN", "length": 325 }, "evidence": [ { "id": "A0A8V0YMC8", "url": "https://omabrowser.org/oma/group/A0A8V0YMC8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9CZI9-1", "protein_name": "Apoptosis-enhancing nuclease", "gene_name": "Aen", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVAGEVPESTQCPSLTSLNTKDVVRRRHKRRSRQHQRFMARKALLQEQELLSTAPGPGLCLLPSPSQMPAVTEASDSRRQRPKARSGSNGLCSKKSVPREAPRPGPIKCVAIDCEMVGTGPQGRVSELARCSVVSYSGDVLYDKYIRPEMPIVDYRTRWSGITRQHMHKAIPFQVAQKEILKLLKGKVVVGHALHNDFQALKYVHPRSQTRDTTYVPNLLSQPSSLIRTRVSLKDLALNLLHKKIQVGHQGHSSVEDAMTAMELYQLVEVQWEQQVASSAQAPAEDRGPDSSTDVEQYMDDQYWPEDLTQSTGAETNGGPDRQEGEEGQGARSAPP", "length": 336 }, "evidence": [ { "id": "A0A8V0YMC8", "url": "https://omabrowser.org/oma/group/A0A8V0YMC8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMC8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMC8" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMC8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMC8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "RNA processing", "id": "GO:0006396", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006396", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMC8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMC8" } ], "pmid": "" }, { "name": "intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator", "id": "GO:0042771", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042771", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMC8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMC8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "nucleic acid binding", "id": "GO:0003676", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003676", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMC8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMC8" } ], "pmid": "" }, { "name": "exonuclease activity", "id": "GO:0004527", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004527", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMC8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMC8" } ], "pmid": "" }, { "name": "3'-5'-RNA exonuclease activity", "id": "GO:0000175", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000175", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMC8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMC8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 253, "end_pos": 255, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YMC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMC8" }, { "id": "SM00479", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00479" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Exonuclease", "eco_id": "ECO_0000259", "start_pos": 131, "end_pos": 297, "start_aa": "Lys", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 311 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 253, "end_pos": 255 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YMD9-1", "uniprot_ac": "A0A8V0YMD9", "uniprot_id": "A0A8V0YMD9_CHICK", "mass": { "chemical_mass": 24169.0, "monoisotopic_mass": 24169.0 }, "refseq": {}, "gene_names": [ { "name": "COMMD7", "type": "recommended", "evidence": [ { "id": "A0A8V0YMD9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMD9" } ] } ], "protein_names": [ { "name": "COMM domain containing 7", "type": "synonym", "evidence": [ { "id": "A0A8V0YMD9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMD9/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMD9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMD9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "COMMD7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMD9", "locus": { "chromosome": "20", "start_pos": 10581766, "end_pos": 10587826, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013412", "url": "https://www.ensembl.org/id/ENSGALG00010013412" } ] } } ], "crossref": [ { "id": "A0A8V0YMD9", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YMD9", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd04755", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04755", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR017920", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017920", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037358", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037358", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047155", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047155", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YMC9", "url": "https://www.orthodb.org/?gene=A0A8V0YMC9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YMD4", "url": "https://www.orthodb.org/?gene=A0A8V0YMD4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YMD9", "url": "https://www.orthodb.org/?gene=A0A8V0YMD9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16231", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16231", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16231:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16231:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07258", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07258", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21672", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21672", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-8951664", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8951664", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YMC9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMC9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YMC9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMC9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YMD4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMD4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YMD4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMD4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YMD9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMD9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YMD9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMD9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLRLSRAVRCGVGGGPGGAGAAMGLLSVGRDAGPEAGSGDVQHLNQLSAEQFSALTEVLFSFLTEPKEVERFLTQLSDFAAMNKISLGPLKNIVKSILLVPNGALKRNLSPEQVRADFVALGLSEEKASYFAEQWKLNAPTLTRLAVGQTLMINQLIDMEWKFGVTAGSSELEKVGSIFLQLKLVIKKGSQMENVYVELTLPQFYSFLHEMERAKTTLESFS", "length": 222, "header": "tr|A0A8V0YMD9-1|A0A8V0YMD9_CHICK Isoform 1 of COMM domain containing 7 OS=Gallus gallus OX=9031 GN=COMMD7 PE=1 SV=1 CANONICAL=A0A8V0YMD9-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YMC9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMD9/entry#A0A8V0YMC9-1", "sequence": { "sequence": "MGLLSVGRDAGPEAGSGDVQHLNQLSAEQFSALTEVLFSFLTEPKEVERFLTQLSDFAAMNKISLGPLKNIVKSILLVPNGLSEEKASYFAEQWKLNAPTLTRLAVGQTLMINQLIDMEWKFGVTAGSSELEKVGSIFLQLKLVIKKGSQMENVYVELTLPQFYSFLHEMERAKTTLESFS", "length": 181, "header": "tr|A0A8V0YMC9-1|A0A8V0YMD9_CHICK Computationally mapped isoform of COMM domain containing 7 OS=Gallus gallus OX=9031 GN=COMMD7 PE=1 SV=1 CANONICAL=A0A8V0YMD9-1" }, "locus": { "chromosome": "20", "start_pos": 10587691, "end_pos": 10583039, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032291.1", "url": "https://www.ensembl.org/id/ENSGALT00010032291.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019081.1", "url": "https://www.ensembl.org/id/ENSGALP00010019081.1" } ] } }, { "isoform_ac": "A0A8V0YMD4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMD9/entry#A0A8V0YMD4-1", "sequence": { "sequence": "MGLLSVGRDAGPEAGSGDVQHLNQLSAEVERFLTQLSDFAAMNKISLGPLKNIVKSILLVPNGALKRNLSPEQVRADFVALGLSEEKASYFAEQWKLNAPTLTRLAVGQTLMINQLIDMEWKFGVTAGSSELEKVGSIFLQLKLVIKKGSQMENVYVELTLPQFYSFLHEMERAKTTLESFS", "length": 182, "header": "tr|A0A8V0YMD4-1|A0A8V0YMD4_CHICK Computationally mapped isoform of COMM domain containing 7 OS=Gallus gallus OX=9031 GN=COMMD7 PE=1 SV=1 CANONICAL=A0A8V0YMD9-1" }, "locus": { "chromosome": "20", "start_pos": 10587691, "end_pos": 10583039, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032296.1", "url": "https://www.ensembl.org/id/ENSGALT00010032296.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019086.1", "url": "https://www.ensembl.org/id/ENSGALP00010019086.1" } ] } }, { "isoform_ac": "A0A8V0YMD9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMD9/entry#A0A8V0YMD9-1", "sequence": { "sequence": "MLRLSRAVRCGVGGGPGGAGAAMGLLSVGRDAGPEAGSGDVQHLNQLSAEQFSALTEVLFSFLTEPKEVERFLTQLSDFAAMNKISLGPLKNIVKSILLVPNGALKRNLSPEQVRADFVALGLSEEKASYFAEQWKLNAPTLTRLAVGQTLMINQLIDMEWKFGVTAGSSELEKVGSIFLQLKLVIKKGSQMENVYVELTLPQFYSFLHEMERAKTTLESFS", "length": 222, "header": "tr|A0A8V0YMD9-1|A0A8V0YMD9_CHICK Isoform 1 of COMM domain containing 7 OS=Gallus gallus OX=9031 GN=COMMD7 PE=1 SV=1 CANONICAL=A0A8V0YMD9-1" }, "locus": { "chromosome": "20", "start_pos": 10587757, "end_pos": 10583039, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032301.1", "url": "https://www.ensembl.org/id/ENSGALT00010032301.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019091.1", "url": "https://www.ensembl.org/id/ENSGALP00010019091.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-8951664", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8951664", "resource": "Reactome", "description": "Neddylation" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "negative regulation of DNA-templated transcription", "id": "GO:0045892", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045892", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMD9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMD9" } ], "pmid": "" }, { "name": "tumor necrosis factor-mediated signaling pathway", "id": "GO:0033209", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033209", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMD9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMD9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "NF-kappaB binding", "id": "GO:0051059", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051059", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMD9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMD9" } ], "pmid": "" } ] }, { 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gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052535.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015134074", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015134074" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMF7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMF7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "KIAA2022", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMF7", "locus": {} } ], "crossref": [ { "id": "ENSGALG00000007755", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000007755", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "422325", "url": "https://www.ncbi.nlm.nih.gov/gene/422325", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": 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Classification" ] }, { "id": "PTHR46946:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46946:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15735", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15735", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015134074", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015134074", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YMF7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMF7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YMF7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMF7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NRB4", "url": "https://www.uniprot.org/uniprotkb/F1NRB4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NRB4-1", "url": "https://www.uniprot.org/uniprotkb/F1NRB4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDDQQEQDCASEDQETILINGVKENEPRTSDGEERPYSAADTTDAFPALTAAPKETQACHRVLPPLPAKKPCSLSPPSPLRLTDVPEHTSDDSSAHAISLTSCVTKGMSSWSLPGDCEKAPFSMMEPGGMSALTGDCLMQPSRTCLGCFIESKDGIDAEPGISLKVGDINRDYDTCSVSDIGIHCMSTGETMRYGDQLLSDQLLSFPMHKSRAADKRDAEKSDSDSEDPTQKNYYEGLLLDKCNGEEPLLTNPNQEWGYFESFISESKIELLDLCSKNELSVNLFSEEDVDNYMFDDDDSTLGSDVCSLKIRYESFQDNVREKTTALQEDAQFNFFPSVFGNCTKRDSRSTLKRGPGGATDPSQFKSEEGIIWGEEEEDGEEEDGEEEEKAALNKSCNSTEVVQYVGPKRSHFLDSVNSTEDSGEFSDDSTCTESSYDVLRDIKDCSRYLSRDHSSSFIQQNYGLRAKRKVRYSDDYLYDVDSIENEKILDKKEWLPDGPKEEDDDEWCPKKRRKVSRKEPPVIIKYIIINRFKGEKHMLVKLSKVDANETTVTLNEELLSKYEKLAPLKGFWQERQQSRLDLLRSSLYHKQNFYLNGSDASFLPHPRKRKCKLANRHRIQRIKAIEQSVNKLGSCSSDHKQPCSSKEDAGLKGLQALAIATPSCANGLHVNDITDIAAVKCKSQEREYKGTERKVLRRIKFKSEARLKCKKIKADASVVEGCPALGDQDSAVHLKDDNIPCASDSSHHPECHEDKIAKNSPFLPSTSSSDKPLPSANITTNVPLIPGGYLQTLLDASDLSSSTGISYFAQHPSEQQHPLPSIIPADKPFTALQPSQSCVLSPPSESELQQSPGHLEMEQSTFGSVWPASKAAGSNRQEFTGELQDTAALTGEFGGAAGTDGLPASGYPQVNLNSSKLLYQKNYMPDSQQVQPDDSYQSCHFNNGEGRFHFQRGTLSTDDGRLISFDSVGSLSVSSSNYSSLKSCEKDGDDDINDDFLAHCSPKLVIQQSIDEITPLKESTDLLDISNFTPDKFRQSSLSEMSPPDTPNLSPQIAGSDTKPLGTLKGFPESAQAALSSSEKVKWNCGVLQTEEQADNGFTLNNHQFQFHMFNDEDSVSLLEKRPCLSTFNEPSGQISTNSKVSKSKRKSSSSKNAGTNQSSSQKTTRKKSPKTNKGTDKPQGKNSRQAPKSTRKGKNAASLSSEKAQVGGSRAVSQLASPASAPKGLAEGIQHSSQATGKLGKHNGLAGEWALGKDSGTAWSETSLGSTTGLLDDDQREFEEPSNILSNIASGMADVQRFMMASIEPLWGPVNHNSVPDIFRSPESNSLKLKTLKILAGTPQESKKKANSSSPGMAKNHKSNNKGSSKNSKAATCDPGRPNCSAGYNTDIHSPFFDKNYSNLSTLGNNGPTHKKLYRHKSSSKSLRDENCKIKRTDREQTHKDPPVTASFEKLRESDSILLKAETTFLVFPVFEEETPFSRKKTFDVSFFCLFVFVHSFQNMPCGMLKCKC", "length": 1511, "header": "tr|A0A8V0YMF7-1|A0A8V0YMF7_CHICK Isoform 1 of Neurite extension and migration factor OS=Gallus gallus OX=9031 GN=KIAA2022 PE=4 SV=1 CANONICAL=A0A8V0YMF7-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YMF7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMF7/entry#A0A8V0YMF7-1", "sequence": { "sequence": "MDDQQEQDCASEDQETILINGVKENEPRTSDGEERPYSAADTTDAFPALTAAPKETQACHRVLPPLPAKKPCSLSPPSPLRLTDVPEHTSDDSSAHAISLTSCVTKGMSSWSLPGDCEKAPFSMMEPGGMSALTGDCLMQPSRTCLGCFIESKDGIDAEPGISLKVGDINRDYDTCSVSDIGIHCMSTGETMRYGDQLLSDQLLSFPMHKSRAADKRDAEKSDSDSEDPTQKNYYEGLLLDKCNGEEPLLTNPNQEWGYFESFISESKIELLDLCSKNELSVNLFSEEDVDNYMFDDDDSTLGSDVCSLKIRYESFQDNVREKTTALQEDAQFNFFPSVFGNCTKRDSRSTLKRGPGGATDPSQFKSEEGIIWGEEEEDGEEEDGEEEEKAALNKSCNSTEVVQYVGPKRSHFLDSVNSTEDSGEFSDDSTCTESSYDVLRDIKDCSRYLSRDHSSSFIQQNYGLRAKRKVRYSDDYLYDVDSIENEKILDKKEWLPDGPKEEDDDEWCPKKRRKVSRKEPPVIIKYIIINRFKGEKHMLVKLSKVDANETTVTLNEELLSKYEKLAPLKGFWQERQQSRLDLLRSSLYHKQNFYLNGSDASFLPHPRKRKCKLANRHRIQRIKAIEQSVNKLGSCSSDHKQPCSSKEDAGLKGLQALAIATPSCANGLHVNDITDIAAVKCKSQEREYKGTERKVLRRIKFKSEARLKCKKIKADASVVEGCPALGDQDSAVHLKDDNIPCASDSSHHPECHEDKIAKNSPFLPSTSSSDKPLPSANITTNVPLIPGGYLQTLLDASDLSSSTGISYFAQHPSEQQHPLPSIIPADKPFTALQPSQSCVLSPPSESELQQSPGHLEMEQSTFGSVWPASKAAGSNRQEFTGELQDTAALTGEFGGAAGTDGLPASGYPQVNLNSSKLLYQKNYMPDSQQVQPDDSYQSCHFNNGEGRFHFQRGTLSTDDGRLISFDSVGSLSVSSSNYSSLKSCEKDGDDDINDDFLAHCSPKLVIQQSIDEITPLKESTDLLDISNFTPDKFRQSSLSEMSPPDTPNLSPQIAGSDTKPLGTLKGFPESAQAALSSSEKVKWNCGVLQTEEQADNGFTLNNHQFQFHMFNDEDSVSLLEKRPCLSTFNEPSGQISTNSKVSKSKRKSSSSKNAGTNQSSSQKTTRKKSPKTNKGTDKPQGKNSRQAPKSTRKGKNAASLSSEKAQVGGSRAVSQLASPASAPKGLAEGIQHSSQATGKLGKHNGLAGEWALGKDSGTAWSETSLGSTTGLLDDDQREFEEPSNILSNIASGMADVQRFMMASIEPLWGPVNHNSVPDIFRSPESNSLKLKTLKILAGTPQESKKKANSSSPGMAKNHKSNNKGSSKNSKAATCDPGRPNCSAGYNTDIHSPFFDKNYSNLSTLGNNGPTHKKLYRHKSSSKSLRDENCKIKRTDREQTHKDPPVTASFEKLRESDSILLKAETTFLVFPVFEEETPFSRKKTFDVSFFCLFVFVHSFQNMPCGMLKCKC", "length": 1511, "header": "tr|A0A8V0YMF7-1|A0A8V0YMF7_CHICK Isoform 1 of Neurite extension and migration factor OS=Gallus gallus OX=9031 GN=KIAA2022 PE=4 SV=1 CANONICAL=A0A8V0YMF7-1" }, "locus": { "chromosome": "4", "start_pos": 12343422, "end_pos": 12334758, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032327.1", "url": "https://www.ensembl.org/id/ENSGALT00010032327.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019111.1", "url": "https://www.ensembl.org/id/ENSGALP00010019111.1" } ] } }, { "isoform_ac": "F1NRB4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMF7/entry#F1NRB4-1", "sequence": { "sequence": "MDDQQEQDCASEDQETILINGVKENEPRTSDGEERPYSAADTTDAFPALTAAPKETQACHRVLPPLPAKKPCSLSPPSPLRLTDVPEHTSDDSSAHAISLTSCVTKGMSSWSLPGDCEKAPFSMMEPGGMSALTGDCLMQPSRTCLGCFIESKDGIDAEPGISLKVGDINRDYDTCSVSDIGIHCMSTGETMRYGDQLLSDQLLSFPMHKSRAADKRDAEKSDSDSEDPTQKNYYEGLLLDKCNGEEPLLTNPNQEWGYFESFISESKIELLDLCSKNELSVNLFSEEDVDNYMFDDDDSTLGSDVCSLKIRYESFQDNVREKTTALQEDAQFNFFPSVFGNCTKRDSRSTLKRGPGGATDPSQFKSEEGIIWGEEEEDGEEEDGEEEEKAALNKSCNSTEVVQYVGPKRSHFLDSVNSTEDSGEFSDDSTCTESSYDVLRDIKDCSRYLSRDHSSSFIQQNYGLRAKRKVRYSDDYLYDVDSIENEKILDKKEWLPDGPKEEDDDEWCPKKRRKVSRKEPPVIIKYIIINRFKGEKHMLVKLSKVDANETTVTLNEELLSKYEKLAPLKGFWQERQQSRLDLLRSSLYHKQNFYLNGSDASFLPHPRKRKCKLANRHRIQRIKAIEQSVNKLGSCSSDHKQPCSSKEDAGLKGLQALAIATPSCANGLHVNDITDIAAVKCKSQEREYKGTERKVLRRIKFKSEARLKCKKIKADASVVEGCPALGDQDSAVHLKDDNIPCASDSSHHPECHEDKIAKNSPFLPSTSSSDKPLPSANITTNVPLIPGGYLQTLLDASDLSSSTGISYFAQHPSEQQHPLPSIIPADKPFTALQPSQSCVLSPPSESELQQSPGHLEMEQSTFGSVWPASKAAGSNRQEFTGELQDTAALTGEFGGAAGTDGLPASGYPQVNLNSSKLLYQKNYMPDSQQVQPDDSYQSCHFNNGEGRFHFQRGTLSTDDGRLISFDSVGSLSVSSSNYSSLKSCEKDGDDDINDDFLAHCSPKLVIQQSIDEITPLKESTDLLDISNFTPDKFRQSSLSEMSPPDTPNLSPQIAGSDTKPLGTLKGFPESAQAALSSSEKVKWNCGVLQTEEQADNGFTLNNHQFQFHMFNDEDSVSLLEKRPCLSTFNEPSGQISTNSKVSKSKRKSSSSKNAGTNQSSSQKTTRKKSPKTNKGTDKPQGKNSRQAPKSTRKGKNAASLSSEKAQVGGSRAVSQLASPASAPKGLAEGIQHSSQATGKLGKHNGLAGEWALGKDSGTAWSETSLGSTTGLLDDDQREFEEPSNILSNIASGMADVQRFMMASIEPLWGPVNHNSVPDIFRSPESNSLKLKTLKILAGTPQESKKKANSSSPGMAKNHKSNNKGSSKNSKAATCDPGRPNCSAGYNTDIHSPFFDKNYSNLSTLGNNGPTHKKLYRHKSSSKSLRDENCKIKRTDREQTHKDPPVTASFEKLR", "length": 1454, "header": "tr|F1NRB4-1|F1NRB4_CHICK Computationally mapped isoform of Neurite extension and migration factor OS=Gallus gallus OX=9031 GN=KIAA2022 PE=4 SV=4 CANONICAL=A0A8V0YMF7-1" }, "locus": { "chromosome": "4", "start_pos": 12343422, "end_pos": 12335619, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032326.1", "url": "https://www.ensembl.org/id/ENSGALT00010032326.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019110.1", "url": "https://www.ensembl.org/id/ENSGALP00010019110.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:422325", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422325", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0AAA9TAX8-1", "protein_name": "Neurite extension and migration factor", "gene_name": "NEXMIF", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MDNQQDKAIVASTNGENTMINGVKENDSEDQDVAMKSFAALEAAAPIQSIPVAQKENLMYPRGLLPLPSKKPCMQSPPSPLGLIEAPEHAANSASVNAISLTSGVAKGLNTWSLPNECEKAPFAIMEPAGMSALNGDCLMQPSRTCLGCFMESKDSVDPEPGISLKVSDLNRDYETCAVSDIGIQCINAGENMKYGEQLLSDQLLGFPLHKSRAGDRREAEKPDIDLEDPGQKSYYEALLLDKCNTEEALLANSNQDWGYFETFISESKIELLDLCSKNELSVNLFSEEDVDNYMFDDDESTLGSDVCSLKIRYESFQDNVRDKTTLLMQEDAQFNFFPSVFTTCPKRESKTGALKQSSDFSQFKVPDVSIIWGEEDKNLDKKKGKEEGQEEKGAEKKDGKDNDEKSALNKPCSGTEVGQFKNLKQGHLANSLEASGNFSDGSSFIEVSFDTMGEIKDCSRYMARDTNSGSSSSQQNYGLRAKRKVRYSEDYLYDVDSLEGEKVNERKEWLPGGSIEEDDDEWCPKKRRKVTRKEPPVIIKYIIINRFKGEKNMLVKLGRVDASETTVNLSENQLNKYAKLAPLKGFWQKKKKQRNSNADSSKTSLCQKQSFEPGSFEMSFLPPARKRKSKLGNRHRIQRIPSIETSASGKQVSFCNDERQANNRKEDGGLKGTLKSAPLAASSCANGSHLNDITGPDSEKVKAQDGQFKAPERKVLNKIKFKSEARLKSKKIKAGQESKPVVQMSPLLENQSSKANSKNEPIAGTSNSSHLSEFHETKVAKNSTFLPTSCSSEMPLSSAHVANNIPVIPGGYLQTLLDASDLSNNTGISYFNHHSPEQNEDRLTQTEKSFVPLQPSQDCVLSSPSESELLQSSQNFKMESSSYGDVWHNKPTSGSQEFMAEVSREIAPTQSSEFGVSQVVSMENSLTATTYSPICLNSGGSSCNKVIYTSVQDTQLSSDDSYQLCHFNNGEVCFPFQQGPVNMDNVRLFSFDSIAPLSVNSSNYCSLSLKSCEKDGDDDIADDFLAHCSPKLVIQQSIDEIAPLKESTDLLDISNFTPDKFRHSSLSEISPPDTPSLSPQITRCENIKTLGTLKGFQEGVPGTLGNMEKIKWDCSTLSQQVQVDDGFTLHNHQFQFHMFNDEDSVSLLQKAPCLSTFNDPSSQISTSNKVSKSRKKSSPSKSGAMNQSSSQKNNRKKSPKSNNKGMEKPPGKTSRQVPKSAKKGKFMAAINGEKMQIGISRGGGQINSISSTGKTLAECIQHGPVASMKMPSQKGLSGDWSLGKESSPGWNDMNMGTSTNNLLDDDQREFQEPSYILSNIASGMADVQRFMMASIEPLWEPMEHHGDPNIFYSPESNSLKLKTLKILAGTPQESKKKVNSGSPGATKNHRSIKGVSKSNGKAAIGDPGRASMSGYNEDSRSAFFDKKLNNLSTLGNNVPTHKKLYRHKTSSKALREEKCKGKRMEREQVHKDEAGTASFEKLR", "length": 1484 }, "evidence": [ { "id": "A0A8V0YMF7", "url": "https://omabrowser.org/oma/group/A0A8V0YMF7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "D3ZGX1-1", "protein_name": "Neurite extension and migration factor", "gene_name": "Nexmif", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDNQQDKVIAASANGENNLINGVKENDSEEQDVAMKSFAALEASTPIQPIPVVQKESPMFPRGLLPLPSKKPCMQSPPSPLGLIEAPDHSATGASVNAISLTSGVAKGLNTWSLPNECEKAPFAIMEPAGISALNGDCLMQPSRTCLGCFMESKEAVDPEPGISLKVGDLNRDYETCAVSDIGIQCINAGENLKYGEQLLSDQLLGFPLHKSRAGDRRESEKPDIDLEDPTQKSYYEALLLDKCNTEEALLANSNQDWGYFETFISESKIELLDLCSKNELSVNLFSEEDVENYMFDDDESTLGSDVCSLKIRYESFQDNVRDKTTLLMQEDAQFNFFPSVFTTCPKRESKSGVLKQSSDLSQFKVPDVSIIWGDEDKNLDKKKGKEEVHEDKSIEKKDEKDNGEKPALNNKPCSGLEVEQFKNLKPDHLTNSLETSGNFSDDSSFIEVSYDAMGEIKDCSRYMARDTNSGSSSSQQNYGLRAKRKVRYSEDYLYDVDSLEGEKVNERKEWPPGGSKEEDDDEWCPKKRRKVTRKEPPVIIKYIIINRFKGEKNMLVKLGKVDASETTVNLSESQLSKYAKLSPLKGFWQKKKKQKNGNTDSVKTPFCQKQSFEPGSFEVSFLPPARKRKSKLGNRHRIQRIQSMEASASSKQVSFGSDQKQASNRKEEGGLKGTPKSALLAAPSSANGSHLRGLIGPDSAKVKAQDTEFKGPERKVLNKIKFKSEARLKSKKIKTGQENKPVVQMSPVSEDPSSKANLKNEVTPGTSNSSHMSEFHETKVVKNSTFLPTTCSSEMPLSSANVATNIPVIPGGYLQTLLDASDLSNNTSISYFTNHSAEQNEASLSQTEKAFAPLQSAQDCVLSSSSDSQLQQSSQNFKMEASNYGSLWPDKDTSGSQEFMTEVSGEIATSQSSEFEATQVVSMENNLTAITYSPVCLNSGGSGCNKVLYASVQDSHLAPDDSYQLCHFNNGEICFPFQQGPISTEDDGQLFSFDSMTPLSVSSSSYCPLSLKSCEKDGDDDINDDFLAHCSPKLVIQQSIDEIAPLKESTDLLDISNFTPDKFRHSSLSEMSPPDTPSLSPQSTRCESIKTLGTMKGFQEGVPGSLSSMEKIKWDCSTLSQQVQADDGFTLNNHQFQFHMFNDEDSVGLLQKNPCLSTFDEPAGQISANNKVSKSRKKTSPGKSGAVSQSSSQKNTRKKSPKASNKGVEKPPSKTSRQVPKSAKKGKYVAAVNGEKMQIGIGHSGGQPNSTSSNGKTLTECIQHGGPVAPMKIPSQKGLSGDWALGKESRPGWNDMSVVTNTNNLLDDDQREFQEPSYILSNIASGMADVQRFMMASMEPLWEPMEHQGESNTFYSPDSNSLKLKTLKILAGTPQESKKKINNGSSGATKNHRSIKAVSKSSGKAAVGDPGHADVSGSSEDSRSAFFDKKYSNMNTLGNNGPTHKKLYRHKSSSKTLRDEKYKGKRVEREQIHKDEAGTTCFEKLRGSSYNLLKAETAFGVLPVFEEETHIFQKDI", "length": 1517 }, "evidence": [ { "id": "A0A8V0YMF7", "url": "https://omabrowser.org/oma/group/A0A8V0YMF7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5DTT1-1", "protein_name": "Neurite extension and migration factor", "gene_name": "Nexmif", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDNQQDKVIAASANGDNNLINGVKNNDSEDQEVAMKSFVALEATTPIQPIPVIQKESPMFPRGLLPPPSKKPCMQSPPSPLALIEAPDHSANSASVNAISLTSGVAKGLNTWSLPNECEKAPFAIMEPAGMSALNGDCLMQPSRTCLGCFMESKEAVDPEPGISLKVSDLNRDYETCAVSDIGIQCINAGENIKYGEQLLSDQLLGFPLHKSRAGDRRESEKPDIDLEDPTQKSYYEALLLDKCNTEEALLANSNQDWGYFETFISESKIELLDLCSKNELSVNLFSEEDVENYMFDDDESTLGSDVCSLKIRYESFQDNVRDKTTLLMQEDAQFNFFPSVFTTCPKRESKSGILKQSSDLSQFKVPDVSIIWGEEDKNLDKKKGKEEVHEDKSIETKDEKDNGEKPALNNKPCGGLEVEQFKNLKADQLTNSLETSGNFSDDSSFIEVSYDAMGEIKDCSRYMARDTNSGSSSSQQNYGLRAKRKVRYSEDYLYDVDSLEGEKVNERKEWPPGGSKEEDDDEWCPKKRRKVTRKEPPVIIKYIIINRFKGEKNMLVKLSKVDASETTVNLSENQLSKYAKLSPLKGFWQKKKKQKNSNTDSVKTPLCQKQSFEPGSFEVSFLPPARKRKSKLGNRHRIQRIQSVETSASSKQVSFCSDQKQACNRKEDGVKGTPKSALLTDPSCANGSHLRGLIVSDSVKVKAQDTEFKGPERKVLNKIKFKSEARLKSKKIKAGQENKPVVQMSPVSEDTSSKANLKNEVTPGTSNSSHMSEFHETKVKNSTFLPTTCSSEMPLSSANVATNIPVIPGGYLQTLLDASDLSNNTSISYFTNHSAEQNEGSLTQTEKAFVPLQSAQDCVLSSSSDSQLQQSSQNFKMEASNFGSLWPDKDTSGSQEFMTEVSREIATNQSSEFEASQVVSMENNLTAITYSPVCLNSDASGCNKVLYASLQDSHLPPEDLYQLCHFNNGEICFPFQQGPLSTDDDGRLFSFDSMTSLTVSSSNYCSLSLKSCEKDGDDEINDDFLAHCSPKLVIQQSIDEIAPLKESTDLLDISNFTPDKFRHSSLLEMSPPDTPSLSPQSTRCESIKTLGTMKGFQEGVPGSLSTVEKIKWDCNTLSQQAQADDGFTLNSHQFQFHMFNDEDSVGLLQKSPCLSTFDEPAGQINTNSKVSKSRKKTSPGKSGAVSQSSSQKNSRKKSPKASNKGVEKPPSKTSRQVPKSTKKGKYVAAVNGEKMQIGIGHSGGQPNSTSSNAKTLTECIQHGGPVASMKIPSQKGLSGDWALGKESRPGWNDMSVVTNTNNLLDDDQREFQEPSYILSNIASGMADVQRFMMASMEPLWEPMEHQGESNTFYSPDSNSLKLKTLKILAGTPQESKKKVTNGSSGATKNHRSVKAVSKSNGKAAIGEPGHADMPGSSEDSRSAFFDKKYSNVNTLGNNGPTHKKLYRHKSSSKGLRDEKYKGKRVEREQAHKDEAGTTSFEKLRDSNYNLLKAETAFGVLPVFEEETHIFQKDI", "length": 1515 }, "evidence": [ { "id": "A0A8V0YMF7", "url": "https://omabrowser.org/oma/group/A0A8V0YMF7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q5QGS0-1", "protein_name": "Neurite extension and migration factor", "gene_name": "NEXMIF", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDNQQDKAIVASANGENTLINGVKENDSEDQDVAMKSFAALEAAAPIQPTPVAQKETLMYPRGLLPLPSKKPCMQSPPSPLGLIEAPEHAANSASVNAISLTSGIAKGLNTWSLPNECEKAPFAIMEPAGMSALNGDCLMQPSRTCLGCFMESKDAVDPEPGISLKVGDLNRDYETCAVSDIGIQCINAGENMKYGEQLLSDQLLGFPLHKSRAGDRRETEKPDIDLEDPAQKSYYEALLLDKCNTEEALLANSNQDWGYFETFISESKIELLDLCSKNELSVNLFSEEDVDNYMFDDDESTLGSDVCSLKIRYESFQDNVRDKTTLLMQEDAQFNFFPSVFTTCPKRESKSGALKQSSDFSQFKVPDVSIIWGEEDKNLDKKKGKEEGQEDKGVEKKDGKDNGEKPALNKPCSGTEVEQLKNPKQGHLANSLETSGSFSDDSSFIEISYDAMGEIKDCSRYMARDTNSGSSSSQQNYGLRAKRKVRYSEDYLYDVDSLEGEKVNERKEWLPVGSKEEDDDEWCPKKRRKVTRKEPPVIIKYIIINRFKGEKNMLVKLGKVDASETTVNLSENQLNKYAKLAPLKGFWQKKKKQRNTNTDSIKTPFSQKQSFEPGSFEVSFLPPARKRKSKLGNRHRIQRIPSIEISASSKQISLCNDQRHASNHKEDGGLKGTLKSAPLGAPSCANGSHLNDITGPDSVKVKAQDTEFKGPERKVLNKIKFKSEARLKSKKVKAAGQESKPIVQMSPLLENQSSKANLKNEVIPGTSNSSRLSEFHEAKAAKSSTFLPTTCSSEMPLSSANVTTNIPVIPGGYLQTLLDASDLSNNTSISYFSHHSPEQNEGSLTQTEKSFVPLQPTQDCVLTSSSDSELQQSSHNFKMESSNYRNVWPNKATSGTQEFMAEVSREIAPTQSSEFGASQVVSMENNLTPTTYNPICLNSGGSNCNKVLYDSMQDTQLPSDDSYQLCHFNNGEICFPFQQGPVNMDDGRLFSFDSMAPLSVSSSNYCSLSLKSCEKDGDDDITDDFLAHCSPKLVIQQSIDEIAPLKESTDLLDISNFTPDKFRHSSLSEMSPPDTPSLSPQITRCESMKTLGTLKGFQEGVPGPLDSVEKIKWDCSTLSRQVQMEDGFTLNNHQFQFHMFNDEDSVSLLQKNPCLSTFNDPSGQISTNNKVSKSRKKSSPSKSGAMNQSSSQKNTRKKSLKGNNKGIEKPPGKNSRQVPKSTKKGKYMAAINGEKMQIGIGRGGSQTNTISSTGKTLAECIQHGGPMASMKMPSQKGLSGDWALGKESSPGWSDMSMGTNTNSLLDDDQREFQEPSYILSNIASGMADVQRFMMASIEPLWEPMEHHGDPNIFYSPESNSLKLKTLKILAGTPQESKKKINSGSQGATKNHRSIKGVSKSNGKTAIGDPGRANMPGYNEDSRSTFFDKKYSNMSTLGNNGPTHKKLYRHKSSSKALRDEKCKGKHMEREQVHKDESGTASFEKLRDSDYNLLKAETTFWVLPVFEEETRIFQKDI", "length": 1516 }, "evidence": [ { "id": "A0A8V0YMF7", "url": "https://omabrowser.org/oma/group/A0A8V0YMF7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMF7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMF7" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMF7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMF7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "negative regulation of cell-matrix adhesion", "id": "GO:0001953", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001953", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMF7", 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"UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLKKLRRVPGNQSKHRVVCKISILQTTIQEETVRDLLLQLDCHKSMGPDEIHPRVLKELVEVIAEPLSIIYQRSLLTGEVPEDWRLANVTPIYKKGCREDPGNYRPVSLTSVLGKIMEQIVLREIMQHVRDNRGIKPSQHGFTKGRSCLTNLIFYDPVTRLVDEGKAVDVVYLDFSKAFDTVSHSILLQKLADRSLDRYILCWVRNWLEGRAQRVVVNGVKSSWRPVTSGVPQGSVLGPVLFNIFIDDLDEGIECTLSKFADDTKLAGSVDLPEGSEALQRDLDRLDSWAEANGMGFNKTKCRVLHFGCNNPRQRYRLGAEWLEDCVEEMDLGVLIDARLNMSQQCTQVAKKANGILACIRNSVASRNREVIIPLYSALVRPHLEYCVQFWGPHCKKDIEALERVQRRATKLVRGLEHRPYEERLKELGLFSLEKRRLRGDLIALYNYLKGGCGELGVSLFSRVTSDRTRGNGFKLRQGRFRLDVRKYYFSERVVRHWNGLPREVVESPSLVVFKERLDVVLRDMV", "length": 526, "header": "tr|A0A8V0YMG2-1|A0A8V0YMG2_CHICK Isoform 1 of Reverse transcriptase domain-containing protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0YMG2-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YMG2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMG2/entry#A0A8V0YMG2-1", "sequence": { "sequence": 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"ENSGALP00010019116.1", "url": "https://www.ensembl.org/id/ENSGALP00010019116.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 11, "end_pos": 13, "annotation": "n_glycosylation_sequon" }, { "start_pos": 298, "end_pos": 300, "annotation": "n_glycosylation_sequon" }, { "start_pos": 341, "end_pos": 343, "annotation": "n_glycosylation_sequon" }, { "start_pos": 88, "end_pos": 90, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YMG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMG2" }, { "id": "PS50878", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50878" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Reverse transcriptase", "eco_id": "ECO_0000259", "start_pos": 73, "end_pos": 327, "start_aa": "Arg", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 11, "end_pos": 13 }, { "start_pos": 298, "end_pos": 300 }, { "start_pos": 341, "end_pos": 343 }, { "start_pos": 88, "end_pos": 90 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": 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"table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YMG5-1", "uniprot_ac": "A0A8V0YMG5", "uniprot_id": "A0A8V0YMG5_CHICK", "mass": { "chemical_mass": 113248.0, "monoisotopic_mass": 113248.0 }, "refseq": { "ac": "XP_004937940", "name": "protein bicaudal D homolog 1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004937940" }, "gene_names": [ { "name": "BICD1", "type": "recommended", "evidence": [ { "id": "A0A8V0YMG5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMG5" } ] }, { "name": "BICD1", "type": "synonym", "evidence": [ { "id": "XP_004937940", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004937940" } ] } ], "protein_names": [ { "name": "BICD cargo adaptor 1", "type": "synonym", "evidence": [ { "id": "A0A8V0YMG5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMG5/entry#names_and_taxonomy" } ] }, { "name": "protein bicaudal D homolog 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_004937940", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004937940" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004937940", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004937940" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMG5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMG5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "BICD1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMG5", "locus": { "chromosome": "1", "start_pos": 59126656, "end_pos": 59320047, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010015918", "url": "https://www.ensembl.org/id/ENSGALG00010015918" } ] } } ], "crossref": [ { "id": "A0A8V0YMG5", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YMG5", "database": "AlphaFoldDB", "categories": [] }, { "id": "427919", "url": "https://www.ncbi.nlm.nih.gov/gene/427919", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR018477", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018477", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:427919", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427919", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "KAEHDCE", "url": "https://omabrowser.org/oma/group/KAEHDCE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YMG5", "url": "https://www.orthodb.org/?gene=A0A8V0YMG5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YMH5", "url": "https://www.orthodb.org/?gene=A0A8V0YMH5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YU86", "url": "https://www.orthodb.org/?gene=A0A8V0YU86", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YU91", "url": "https://www.orthodb.org/?gene=A0A8V0YU91", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YVT0", "url": "https://www.orthodb.org/?gene=A0A8V0YVT0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z0M1", "url": "https://www.orthodb.org/?gene=A0A8V0Z0M1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31233", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31233", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31233:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31233:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF09730", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09730", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-6811436", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6811436", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_004937940", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004937940", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YMG5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMG5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YMG5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMG5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YMH5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMH5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YMH5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMH5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YU86", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YU86", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YU86-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YU86-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YU91", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YU91", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YU91-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YU91-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YVT0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YVT0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YVT0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YVT0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z0M1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z0M1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z0M1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z0M1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAEEVLQGADHYKSEIERLTRELSETTHEKIQAAEYGLVVLEEKLTLKQQYDELEAEYDGLKQELEQLKEAFGQSFSIHRKVAEDGETREETLLQESASKEAYYLGKILEMQNELKQSKAVVTNVQAENERLTAIVQDLKENNEMVELQRIRMKDEIREYKFREARLLQDYTELEEENITLQKLVSTLKQNQVEYEGLKHEIKRFEEETVLLNSQLEDAIRLKEIAEHQLEEALETLKNEREQKNNLRKELSQYINLNDSMYNNHINISVDGLKFAEDTSEPNNDDKMNGHIHGSLVKLNGDYRTPTSRKGESLHPVSDLFSELNISEIQKLKQQLMQVEREKAILLANLQESQTQLEHTKGALTEQHERVHRLTEHVNAMRGLQSNKEMKTEHDCEKGRDPSEEAHDYEVDINGLEILECKYKVAVTEVIDLKAEIKALKEKYNNYVENYTEEKAKYESRIQTYNEQVTSLEKSTKESQEKMVHMEKELQRMTSIANENHNTLNTAQDELVTFSEELAQLYHHVCLCNNETPNRVMLDYYRQSRVTRSGSLKGPDDPRGLLSPRLARRGMASPVEARTPTEQVTKEAAEPGKEQSPTKTPTISPVITAPPSSPVSDSSDIRKEPMNIYNLNAIIRDQIKHLQKAVDRSLQLSRQRAAARELAPMIDKDKEALMEEILKLKSLLSTKREQIATLRAVLKANKQTAEVALANLKNKYENEKAMVTETMTKLRNELKALKEDAATFSSLRAMFATRCDEYVTQLDEMQRQLAAAEDEKKTLNSLLRMAIQQKLALTQRLEDLEFDHEQSRRSKGKLGKSKIGSPKVSEEASATVPTIDTFLLHSQGPQQPNLLVSSGTQRKRLFSPSLCDQSHPRTSGTYLQKLLRAPPHPASTESYLLRGPPSMSEFIHGHRLSKEKRLTVATPVLVLFQKSSHIPALSVPLSTVSLSLLLTPNLHMQRKRKRKQSGVHATKVRVVPSERVDNPALLPHR", "length": 990, "header": "tr|A0A8V0YMG5-1|A0A8V0YMG5_CHICK Isoform 1 of BICD cargo adaptor 1 OS=Gallus gallus OX=9031 GN=BICD1 PE=3 SV=1 CANONICAL=A0A8V0YMG5-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YMG5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMG5/entry#A0A8V0YMG5-1", "sequence": { "sequence": "MAAEEVLQGADHYKSEIERLTRELSETTHEKIQAAEYGLVVLEEKLTLKQQYDELEAEYDGLKQELEQLKEAFGQSFSIHRKVAEDGETREETLLQESASKEAYYLGKILEMQNELKQSKAVVTNVQAENERLTAIVQDLKENNEMVELQRIRMKDEIREYKFREARLLQDYTELEEENITLQKLVSTLKQNQVEYEGLKHEIKRFEEETVLLNSQLEDAIRLKEIAEHQLEEALETLKNEREQKNNLRKELSQYINLNDSMYNNHINISVDGLKFAEDTSEPNNDDKMNGHIHGSLVKLNGDYRTPTSRKGESLHPVSDLFSELNISEIQKLKQQLMQVEREKAILLANLQESQTQLEHTKGALTEQHERVHRLTEHVNAMRGLQSNKEMKTEHDCEKGRDPSEEAHDYEVDINGLEILECKYKVAVTEVIDLKAEIKALKEKYNNYVENYTEEKAKYESRIQTYNEQVTSLEKSTKESQEKMVHMEKELQRMTSIANENHNTLNTAQDELVTFSEELAQLYHHVCLCNNETPNRVMLDYYRQSRVTRSGSLKGPDDPRGLLSPRLARRGMASPVEARTPTEQVTKEAAEPGKEQSPTKTPTISPVITAPPSSPVSDSSDIRKEPMNIYNLNAIIRDQIKHLQKAVDRSLQLSRQRAAARELAPMIDKDKEALMEEILKLKSLLSTKREQIATLRAVLKANKQTAEVALANLKNKYENEKAMVTETMTKLRNELKALKEDAATFSSLRAMFATRCDEYVTQLDEMQRQLAAAEDEKKTLNSLLRMAIQQKLALTQRLEDLEFDHEQSRRSKGKLGKSKIGSPKVSEEASATVPTIDTFLLHSQGPQQPNLLVSSGTQRKRLFSPSLCDQSHPRTSGTYLQKLLRAPPHPASTESYLLRGPPSMSEFIHGHRLSKEKRLTVATPVLVLFQKSSHIPALSVPLSTVSLSLLLTPNLHMQRKRKRKQSGVHATKVRVVPSERVDNPALLPHR", "length": 990, "header": "tr|A0A8V0YMG5-1|A0A8V0YMG5_CHICK Isoform 1 of BICD cargo adaptor 1 OS=Gallus gallus OX=9031 GN=BICD1 PE=3 SV=1 CANONICAL=A0A8V0YMG5-1" }, "locus": { "chromosome": "1", "start_pos": 59320032, "end_pos": 59132464, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010038359.1", "url": "https://www.ensembl.org/id/ENSGALT00010038359.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010022174.1", "url": "https://www.ensembl.org/id/ENSGALP00010022174.1" } ] } }, { "isoform_ac": "A0A8V0YMH5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMG5/entry#A0A8V0YMH5-1", "sequence": { "sequence": "MAAEEVLQGADHYKSEIERLTRELSETTHEKIQAAEYGLVVLEEKLTLKQQYDELEAEYDGLKQELEQLKEAFGQSFSIHRKVAEDGETREETLLQESASKEAYYLGKILEMQNELKQSKAVVTNVQAENERLTAIVQDLKENNEMVELQRIRMKDEIREYKFREARLLQDYTELEEENITLQKLVSTLKQNQVEYEGLKHEIKRFEEETVLLNSQLEDAIRLKEIAEHQLEEALETLKNEREQKNNLRKELSQYINLNDSMYNNHINISVDGLKFAEDTSEPNNDDKMNGHIHGSLVKLNGDYRTPTSRKGESLHPVSDLFSELNISEIQKLKQQLMQVEREKAILLANLQESQTQLEHTKGALTEQHERVHRLTEHVNAMRGLQSNKEMKTEHDCEKGRDPSEEAHDYEVDINGLEILECKYKVAVTEVIDLKAEIKALKEKYNNYVENYTEEKAKYESRIQTYNEQVTSLEKSTKESQEKMVHMEKELQRMTSIANENHNTLNTAQDELVTFSEELAQLYHHVCLCNNETPNRVMLDYYRQSRVTRSGSLKGPDDPRGLLSPRLARRGMASPVEARTPTEQVTKEAAEPGKEQSPTKTPTISPVITAPPSSPVSDSSDIRKEPMNIYNLNAIIRDQIKHLQKAVDRSLQLSRQRAAARELAPMIDKDKEALMEEILKLKSLLSTKREQIATLRAVLKANKQTAEVALANLKNKYENEKAMVTETMTKLRNELKALKEDAATFSSLRAMFATRCDEYVTQLDEMQRQLAAAEDEKKTLNSLLRMAIQQKLALTQRLEDLEFDHEQSRRSKGKLGKSKIGSPKDFNLFPVEFFGRPFMKSNKNQVTNEQKIKEKI", "length": 856, "header": "tr|A0A8V0YMH5-1|A0A8V0YMH5_CHICK Computationally mapped isoform of BICD cargo adaptor 1 OS=Gallus gallus OX=9031 GN=BICD1 PE=3 SV=1 CANONICAL=A0A8V0YMG5-1" }, "locus": { "chromosome": "1", "start_pos": 59320032, "end_pos": 59127660, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010038369.1", "url": "https://www.ensembl.org/id/ENSGALT00010038369.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010022184.1", "url": "https://www.ensembl.org/id/ENSGALP00010022184.1" } ] } }, { "isoform_ac": "A0A8V0YU86-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMG5/entry#A0A8V0YU86-1", "sequence": { "sequence": "MAAEEVLQGADHYKSEIERLTRELSETTHEKIQAAEYGLVVLEEKLTLKQQYDELEAEYDGLKQELEQLKEAFGQSFSIHRKVAEDGETREETLLQESASKEAYYLGKILEMQNELKQSKAVVTNVQAENERLTAIVQDLKENNEMVELQRIRMKDEIREYKFREARLLQDYTELEEENITLQKLVSTLKQNQVEYEGLKHEIKRFEEETVLLNSQLEDAIRLKEIAEHQLEEALETLKNEREQKNNLRKELSQYINLNDSMYNNHINISVDGLKFAEDTSEPNNDDKMNGHIHGSLVKLNGDYRTPTSRKGESLHPVSDLFSELNISEIQKLKQQLMQVEREKAILLANLQESQTQLEHTKGALTEQHERVHRLTEHVNAMRGLQSNKEMKTEHDCEKGRDPSEEAHDYEVDINGLEILECKYKVAVTEVIDLKAEIKALKEKYNNYVENYTEEKAKYESRIQTYNEQVTSLEKSTKESQEKMVHMEKELQRMTSIANENHNTLNTAQDELVTFSEELAQLYHHVCLCNNETPNRVMLDYYRQSRVTRSGSLKGPDDPRGLLSPRLARRGMASPVEARTPTEQVTKEAAEPGKEQSPTKTPTISPVITAPPSSPVSDSSDIRKEPMNIYNLNAIIRDQIKHLQKAVDRSLQLSRQRAAARELAPMIDKDKEALMEEILKLKSLLSTKREQIATLRAVLKANKQTAEVALANLKNKYENEKAMVTETMTKLRNELKALKEDAATFSSLRAMFATRCDEYVTQLDEMQRQLAAAEDEKKTLNSLLRMAIQQKLALTQRLEDLEFDHEQSRRSKGKLGKSKIGSPKVSEEASATVPTIDTFLLHSQGPQQPNLLVSSGTQRKSPSALPEEQPHSSSQCAPLNCLSKPPPYP", "length": 889, "header": "tr|A0A8V0YU86-1|A0A8V0YU86_CHICK Computationally mapped isoform of BICD cargo adaptor 1 OS=Gallus gallus OX=9031 GN=BICD1 PE=3 SV=1 CANONICAL=A0A8V0YMG5-1" }, "locus": { "chromosome": "1", "start_pos": 59320032, "end_pos": 59132576, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010038363.1", "url": "https://www.ensembl.org/id/ENSGALT00010038363.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010022178.1", "url": "https://www.ensembl.org/id/ENSGALP00010022178.1" } ] } }, { "isoform_ac": "A0A8V0YU91-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMG5/entry#A0A8V0YU91-1", "sequence": { "sequence": "MAAEEVLQGADHYKSEIERLTRELSETTHEKIQAAEYGLVVLEEKLTLKQQYDELEAEYDGLKQELEQLKEAFGQSFSIHRKVAEDGETREETLLQESASKEAYYLGKILEMQNELKQSKAVVTNVQAENERLTAIVQDLKENNEMVELQRIRMKDEIREYKFREARLLQDYTELEEENITLQKLVSTLKQNQVEYEGLKHEIKRFEEETVLLNSQLEDAIRLKEIAEHQLEEALETLKNEREQKNNLRKELSQYINLNDSMYNNHINISVDGLKFAEDTSEPNNDDKMNGHIHGSLVKLNGDYRTPTSRKGESLHPVSDLFSELNISEIQKLKQQLMQVEREKAILLANLQESQTQLEHTKGALTEQHERVHRLTEHVNAMRGLQSNKEMKTEHDCEKGRDPSEEAHDYEVDINGLEILECKYKVAVTEVIDLKAEIKALKEKYNNYVENYTEEKAKYESRIQTYNEQVTSLEKSTKESQEKMVHMEKELQRMTSIANENHNTLNTAQDELVTFSEELAQLYHHVCLCNNETPNRVMLDYYRQSRVTRSGSLKGPDDPRGLLSPRLARRGMASPVEARTPTEQVTKEAAEPGKEQSPTKTPTISPVITAPPSSPVSDSSDIRKEPMNIYNLNAIIRDQIKHLQKAVDRSLQLSRQRAAARELAPMIDKDKEALMEEILKLKSLLSTKREQIATLRAVLKANKQTAEVALANLKNKYENEKAMVTETMTKLRNELKALKEDAATFSSLRAMFATRCDEYVTQLDEMQRQLAAAEDEKKTLNSLLRMAIQQKLALTQRLEDLEFDHEQSRRSKGKLGKSKIGSPKVSEEASATVPTIDTFLLHSQGPQQPNLLVSSGTQRKRLSAACCLHTATRLTTSQGARLPECQS", "length": 887, "header": "tr|A0A8V0YU91-1|A0A8V0YU91_CHICK Computationally mapped isoform of BICD cargo adaptor 1 OS=Gallus gallus OX=9031 GN=BICD1 PE=3 SV=1 CANONICAL=A0A8V0YMG5-1" }, "locus": { "chromosome": "1", "start_pos": 59320032, "end_pos": 59132658, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010038368.1", "url": "https://www.ensembl.org/id/ENSGALT00010038368.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010022183.1", "url": "https://www.ensembl.org/id/ENSGALP00010022183.1" } ] } }, { "isoform_ac": "A0A8V0YVT0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMG5/entry#A0A8V0YVT0-1", "sequence": { "sequence": "MAAEEVLQGADHYKSEIERLTRELSETTHEKIQAAEYGLVVLEEKLTLKQQYDELEAEYDGLKQELEQLKEAFGQSFSIHRKVAEDGETREETLLQESASKEAYYLGKILEMQNELKQSKAVVTNVQAENERLTAIVQDLKENNEMVELQRIRMKDEIREYKFREARLLQDYTELEEENITLQKLVSTLKQNQVEYEGLKHEIKRFEEETVLLNSQLEDAIRLKEIAEHQLEEALETLKNEREQKNNLRKELSQYINLNDSMYNNHINISVDGLKFAEDTSEPNNDDKMNGHIHGSLVKLNGDYRTPTSRKGESLHPVSDLFSELNISEIQKLKQQLMQVEREKAILLANLQESQTQLEHTKGALTEQHERVHRLTEHVNAMRGLQSNKEMKTEHDCEKGRDPSEEAHDYEVDINGLEILECKYKVAVTEVIDLKAEIKALKEKYNNYVENYTEEKAKYESRIQTYNEQVTSLEKSTKESQEKMVHMEKELQRMTSIANENHNTLNTAQDELVTFSEELAQLYHHVCLCNNETPNRVMLDYYRQSRVTRSGSLKGPDDPRGLLSPRLARRGMASPVEARTPTEQVTKEAAEPGKEQSPTKTPTISPVITAPPSSPVSDSSDIRKEPMNIYNLNAIIRDQIKHLQKAVDRSLQLSRQRAAARELAPMIDKDKEALMEEILKLKSLLSTKREQIATLRAVLKANKQTAEVALANLKNKYENEKAMVTETMTKLRNELKALKEDAATFSSLRAMFATRCDEYVTQLDEMQRQLAAAEDEKKTLNSLLRMAIQQKLALTQRLEDLEFDHEQSRRSKGKLGKSKIGSPKFLVDCQQPAASIPPHGSQLARGPDCQNVRTW", "length": 855, "header": "tr|A0A8V0YVT0-1|A0A8V0YVT0_CHICK Computationally mapped isoform of BICD cargo adaptor 1 OS=Gallus gallus OX=9031 GN=BICD1 PE=3 SV=1 CANONICAL=A0A8V0YMG5-1" }, "locus": { "chromosome": "1", "start_pos": 59320032, "end_pos": 59134771, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010038357.1", "url": "https://www.ensembl.org/id/ENSGALT00010038357.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010022172.1", "url": "https://www.ensembl.org/id/ENSGALP00010022172.1" } ] } }, { "isoform_ac": "A0A8V0Z0M1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMG5/entry#A0A8V0Z0M1-1", "sequence": { "sequence": "MAAEEVLQGADHYKSEIERLTRELSETTHEKIQAAEYGLVVLEEKLTLKQQYDELEAEYDGLKQELEQLKEAFGQSFSIHRKVAEDGETREETLLQESASKEAYYLGKILEMQNELKQSKAVVTNVQAENERLTAIVQDLKENNEMVELQRIRMKDEIREYKFREARLLQDYTELEEENITLQKLVSTLKQNQVEYEGLKHEIKRFEEETVLLNSQLEDAIRLKEIAEHQLEEALETLKNEREQKNNLRKELSQYINLNDSMYNNHINISVDGLKFAEDTSEPNNDDKMNGHIHGSLVKLNGDYRTPTSRKGESLHPVSDLFSELNISEIQKLKQQLMQVEREKAILLANLQESQTQLEHTKGALTEQHERVHRLTEHVNAMRGLQSNKEMKTEHDCEKGRDPSEEAHDYEVDINGLEILECKYKVAVTEVIDLKAEIKALKEKYNNYVENYTEEKAKYESRIQTYNEQVTSLEKSTKESQEKMVHMEKELQRMTSIANENHNTLNTAQDELVTFSEELAQLYHHVCLCNNETPNRVMLDYYRQSRVTRSGSLKGPDDPRGLLSPRLARRGMASPVEARTPTEQVTKEAAEPGKEQSPTKTPTISPVITAPPSSPVSDSSDIRKEPMNIYNLNAIIRDQIKHLQKAVDRSLQLSRQRAAARELAPMIDKDKEALMEEILKLKSLLSTKREQIATLRAVLKANKQTAEVALANLKNKYENEKAMVTETMTKLRNELKALKEDAATFSSLRAMFATRCDEYVTQLDEMQRQLAAAEDEKKTLNSLLRMAIQQKLALTQRLEDLEFDHEQSRRSKGKLGKSKIGSPKVSEEASATVPTIDTFLLHSQGPQQPNLLVSSGTQRKRLFSPSLCDQSHPRTSGTYLQKLLRAPPHPASTESYLLRGPPSMSEFIHGHRLSKEKRLTVATPDCQQPAASIPPHGSQLARGPDCQNVSPSALPEEQPHSSSQCAPLNCLSKPPPYP", "length": 978, "header": "tr|A0A8V0Z0M1-1|A0A8V0Z0M1_CHICK Computationally mapped isoform of BICD cargo adaptor 1 OS=Gallus gallus OX=9031 GN=BICD1 PE=3 SV=1 CANONICAL=A0A8V0YMG5-1" }, "locus": { "chromosome": "1", "start_pos": 59320032, "end_pos": 59132576, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010038365.1", "url": "https://www.ensembl.org/id/ENSGALT00010038365.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010022180.1", "url": "https://www.ensembl.org/id/ENSGALP00010022180.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:427919", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427919", "resource": "KEGG Pathway" }, { "id": "R-GGA-6811436", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6811436", "resource": "Reactome", "description": "COPI-independent Golgi-to-ER retrograde traffic" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A4X1VQ10-1", "protein_name": "BICD cargo adaptor 1", "gene_name": "BICD1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAAEEVLQTVDHYKTEIERLTKELTETTHEKIQAAEYGLVVLEEKLTLKQQYDELEAEYDSLKQELEQLKEAFGQSFSIHRKVAEDGETREETLLQESASKEAYYLGKILEMQNELKQSRAVVTNVQAENERLTAVVQDLKENNEMVELQRIRMKDEIREYKFREARLLQDYTELEEENITLQKLVSTLKQNQVEYEGLKHEIKRFEEETVLLNSQLEDAIRLKEIAEHQLEEALETLKNEREQKNSLRKELSQYITLNDNHISISVDGLKFAEDGSEPNNDDKMNGHIHGPLVKLNGDYRTPTLRKGESLHPVSDLFSELNISEIQKLKQQLMQVEREKAILLANLQESQTQLEHTKGALTEQHERVHRLTEHVNAMRGLQSSKELKELDGEKGRDSGEEAHDYEVDINGLEILECKYRVAVTEVIDLKAEIKALKEKYNKSVENYTEEKAKYESKIQTYDEQVTSLEKTTKESGEKMAHMEKELQKMTSIANENHNTLNTAQDELVTFSEELAQLYHHVCLCNNETPNRVMLDYYRQSRVTRSGSLKGPDDPRGLLSPRLARRGVSSPVETRTSPEPVPKENPEASKEPSPTKTPTISPVITAPPSSPVLDTSDIRKEPMNIYNLNAIIRDQIKHLQKAVDRSLQLSRQRAAARELAPMIDKDKEALMEEILKLKSLLSTKREQIATLRAVLKANKQTAEVALANLKNKYENEKAMVTETMTKLRNELKALKEDAATFSSLRAMFATRCDEYVTQLDEMQRQLAAAEDEKKTLNTLLRMAIQQKLALTQRLEDLEFDHEQSRRSKGKLGKSKIGSPKVSGEASVTVPTIDTYLLHSQGPQTPNIRVSSGTQRKRQFSPSLCDQSRPRTSGASYLQNLLRVPPDPTSTESFLLKGPPSMSEFIQGHRLSKEKRLTVAPPDCQQPAASVPPQCSQLAGRQDCPTVSPDVALPEEQPHSSSQCAPLHCLSKPPYP", "length": 974 }, "evidence": [ { "id": "A0A8V0YMG5", "url": "https://omabrowser.org/oma/group/A0A8V0YMG5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8I5ZKI9-1", "protein_name": "BICD cargo adaptor 1", "gene_name": "Bicd1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAAEEALKTVDHYKTEIERLTKELTETTHEKIQAAEYGLVVLEEKLTLKQQYDELEAEYDGLKQELEQLKEAFGQSFSIHRKVAEDGETREETLLQESASKEAYYLNKILEMQNELKQSRAVVTNVQAENERLSAVVQELKENNEMVELQRIRMKDEIREYKFREARLLQDYTELEEENITLQKLVSTLKQNQVEYEGLKHEIKRFEEETVLLNSQLEDAIRLKEIAEHQLEEALETLKNEREQKNNLRKELSQYISLSDNHISISVEGLKFAEDGSEPNNDDKMNGHLHGPLGKLNGDYRAPTARKGESLHPVSDLFSELNISEIQKLKQQLIQVEREKAILLANLQESQTQLEHTKGALTEQHERVHRLTEHVNAMRGLQNSKELKAELDCEKGRNSAEEAHDYEVDINGLEILECKYRVAVTEVIDLKAEIKALKEKYNKSVENYTEEKTKYESKIQMYDEQVTNLEKTSKESGEKMAHMEKELQKMTGIANENHNTLNTAQDELVTFSEELAQLYHHVCLCNNETPNRVMLDYYRQSRVTRSGSLKGPDDPRGLLSPRLSRRGVSSPVESRTSSEPVSKENTETSKEPSPTKTPTISPVITAPPSSPVLDTSDIRKEPMNIYNLNAIIRDQIKHLQKAVDRSLQLSRQRAAARELAPMIDKDKEALMEEILKLKSLLSTKREQIATLRAVLKANKQTAEVALANLKNKYENEKAMVTETMTKLRNELKALKEDAATFSSLRAMFATRCDEYVTQLDEMQRQLAAAEDEKKTLNTLLRMAIQQKLALTQRLEDLEFDHEQSRRSKGKLGKSKIGSPKVSGEAPATVPTIDTYLLHSQGPQIPTIRVSSGTQRKRQFSPSLCDQSRPRTSGASYLQNLLSVPPDPTSTESFLLKGSPSMSELIQGHRLSKEKRLTVAPPAKRDCQQPAASVPPQCSQLAGRQDYPTVSPDIALSKEQPHSSSQCAPLHCLAKPPYP", "length": 978 }, "evidence": [ { "id": "A0A8V0YMG5", "url": "https://omabrowser.org/oma/group/A0A8V0YMG5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8BR07-1", "protein_name": "Protein bicaudal D homolog 1", "gene_name": "Bicd1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAEEALKTVDQYKTEIERLTKELTETTHEKIQAAEYGLVVLEEKLTLKQQYDELEAEYDGLKQELEQLREAFGQSFSIHRKVAEDGETREETLLQESASKEAYYLNKILEMQNELKQSRAVVTNVQAENERLSAVVQELKENNEMVELQRIRMKDEIREYKFREARLLQDYTELEEENITLQKLVSTLKQNQVEYEGLKHEIKRFEEETVLLNSQLEDAIRLKEIAEHQLEEALETLKNEREQKNNLRKELSQYINLSDSHISISVDGLKFAEDGSEPNNDDKMNGHIHGPLGKLNGDYRTPTTRKGESLHPVSDLFSELNISEIQKLKQQLIQVEREKAILLANLQESQTQLEHTKGALTEQHERVHRLTEHVNAMRGLQNSKEIKAELDCEKGRNSAEEAHDYEVDINGLEILECKYRVAVTEVIDLKAEIKALKEKYNKSVENYTEEKTKYESKIQMYDEQVTNLEKTSKESGEKMAHMEKELQKMTGIANENHNTLNTAQDELVTFSEELAQLYHHVCLCNNETPNRVMLDYYRQSRVTRSGSLKGPDDPRGLLSPRLSRRGVSSPVESRTSSEPVSKENTETSKEPSPTKTPTISPVITAPPSSPVLDTSDIRKEPMNIYNLNAIIRDQIKHLQKAVDRSLQLSRQRAAARELAPMIDKDKEALMEEILKLKSLLSTKREQIATLRAVLKANKQTAEVALANLKNKYENEKAMVTETMTKLRNELKALKEDAATFSSLRAMFATRCDEYVTQLDEMQRQLAAAEDEKKTLNTLLRMAIQQKLALTQRLEDLEFDHEQSRRSKGKLGKSKIGSPKIVSSLLPPYRHSAHN", "length": 835 }, "evidence": [ { "id": "A0A8V0YMG5", "url": "https://omabrowser.org/oma/group/A0A8V0YMG5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96G01-1", "protein_name": "Protein bicaudal D homolog 1", "gene_name": "BICD1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAEEVLQTVDHYKTEIERLTKELTETTHEKIQAAEYGLVVLEEKLTLKQQYDELEAEYDSLKQELEQLKEAFGQSFSIHRKVAEDGETREETLLQESASKEAYYLGKILEMQNELKQSRAVVTNVQAENERLTAVVQDLKENNEMVELQRIRMKDEIREYKFREARLLQDYTELEEENITLQKLVSTLKQNQVEYEGLKHEIKRFEEETVLLNSQLEDAIRLKEIAEHQLEEALETLKNEREQKNNLRKELSQYISLNDNHISISVDGLKFAEDGSEPNNDDKMNGHIHGPLVKLNGDYRTPTLRKGESLNPVSDLFSELNISEIQKLKQQLMQVEREKAILLANLQESQTQLEHTKGALTEQHERVHRLTEHVNAMRGLQSSKELKAELDGEKGRDSGEEAHDYEVDINGLEILECKYRVAVTEVIDLKAEIKALKEKYNKSVENYTDEKAKYESKIQMYDEQVTSLEKTTKESGEKMAHMEKELQKMTSIANENHSTLNTAQDELVTFSEELAQLYHHVCLCNNETPNRVMLDYYRQSRVTRSGSLKGPDDPRGLLSPRLARRGVSSPVETRTSSEPVAKESTEASKEPSPTKTPTISPVITAPPSSPVLDTSDIRKEPMNIYNLNAIIRDQIKHLQKAVDRSLQLSRQRAAARELAPMIDKDKEALMEEILKLKSLLSTKREQIATLRAVLKANKQTAEVALANLKNKYENEKAMVTETMTKLRNELKALKEDAATFSSLRAMFATRCDEYVTQLDEMQRQLAAAEDEKKTLNTLLRMAIQQKLALTQRLEDLEFDHEQSRRSKGKLGKSKIGSPKVSGEASVTVPTIDTYLLHSQGPQTPNIRVSSGTQRKRQFSPSLCDQSRPRTSGASYLQNLLRVPPDPTSTESFLLKGPPSMSEFIQGHRLSKEKRLTVAPPDCQQPAASVPPQCSQLAGRQDCPTVSPDTALPEEQPHSSSQCAPLHCLSKPPHP", "length": 975 }, "evidence": [ { "id": "A0A8V0YMG5", "url": "https://omabrowser.org/oma/group/A0A8V0YMG5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 8, "go_terms": [ { "name": "secretory vesicle", "id": "GO:0099503", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099503", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMG5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMG5" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMG5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMG5" } ], "pmid": "" }, { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMG5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMG5" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMG5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMG5" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMG5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMG5" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMG5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMG5" } ], "pmid": "" }, { "name": "trans-Golgi network", "id": "GO:0005802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005802", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMG5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMG5" } ], "pmid": "" }, { "name": "cytoplasmic microtubule", "id": "GO:0005881", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005881", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMG5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMG5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 6, "go_terms": [ { "name": "protein kinase binding", "id": "GO:0019901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019901", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMG5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMG5" } ], "pmid": "" }, { "name": "cytoskeletal anchor activity", "id": "GO:0008093", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008093", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMG5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMG5" } ], "pmid": "" }, { "name": "small GTPase binding", "id": "GO:0031267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031267", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMG5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMG5" } ], "pmid": "" }, { "name": "dynein complex binding", "id": "GO:0070840", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070840", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMG5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMG5" } ], "pmid": "" }, { "name": "dynactin binding", "id": "GO:0034452", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034452", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMG5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMG5" } ], "pmid": "" }, { "name": "dynein intermediate chain binding", "id": "GO:0045505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045505", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMG5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMG5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "positive regulation of protein localization to centrosome", "id": "GO:1904781", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904781", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMG5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMG5" } ], "pmid": "" }, { "name": "positive regulation of receptor-mediated endocytosis", "id": "GO:0048260", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048260", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMG5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMG5" } ], "pmid": "" }, { "name": "virion assembly", "id": "GO:0019068", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019068", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMG5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMG5" } ], "pmid": "" }, { "name": "regulation of microtubule cytoskeleton organization", "id": "GO:0070507", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070507", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMG5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMG5" } ], "pmid": "" }, { "name": "minus-end-directed organelle transport along microtubule", "id": "GO:0072385", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072385", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMG5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMG5" } ], "pmid": "" }, { "name": "microtubule anchoring at microtubule organizing center", "id": "GO:0072393", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072393", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMG5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMG5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 179, "end_pos": 181, "annotation": "n_glycosylation_sequon" }, { "start_pos": 259, "end_pos": 261, "annotation": "n_glycosylation_sequon" }, { "start_pos": 268, "end_pos": 270, "annotation": "n_glycosylation_sequon" }, { "start_pos": 326, "end_pos": 328, "annotation": "n_glycosylation_sequon" }, { "start_pos": 451, "end_pos": 453, "annotation": "n_glycosylation_sequon" }, { "start_pos": 531, "end_pos": 533, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 179, "end_pos": 181 }, { "start_pos": 259, "end_pos": 261 }, { "start_pos": 268, "end_pos": 270 }, { "start_pos": 326, "end_pos": 328 }, { "start_pos": 451, "end_pos": 453 }, { "start_pos": 531, "end_pos": 533 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": 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"categories": [ "Protein" ] } ], "sequence": { "sequence": "MFSAASPVIGDSRTQSSGGPGLQPHGRDFLLLRAAAGCVCRRCRFRVAAEMAAPGDGGTGPGPGPGSGSGLKRLAAAGDLRSVLITSVLNLERLEVDLFRGQHHWVPATRRLFGGQIVGQALVAAARAVSRDLQAHSLHCYFVRAGDPKVPVLYEVERTRTGKSFSVRSVKAIQHGKPIFICQASFQLAQQSPVQHQFTMPTVPPPEELLTQEELIEKFLQNPNLAERYRKHLNKIQAEDVPIDIKPVNPPDIFCAQPQEPKQFFWVRARGYIGETDMKVHCCVAAYISDYAFLGTALLPHRQYNIKFMVSLDHSMWFHAPFRSDHWMLYECESPWAGGCRGLVHGRLWRRDGVLAVTCTQEGVIRVEENPNQSKL", "length": 376, "header": "tr|A0A8V0YMJ0-1|A0A8V0YMJ0_CHICK Isoform 1 of Acyl-coenzyme A thioesterase 8 OS=Gallus gallus OX=9031 GN=ACOT8 PE=1 SV=1 CANONICAL=A0A8V0YMJ0-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YMJ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMJ0/entry#A0A8V0YMJ0-1", "sequence": { "sequence": "MFSAASPVIGDSRTQSSGGPGLQPHGRDFLLLRAAAGCVCRRCRFRVAAEMAAPGDGGTGPGPGPGSGSGLKRLAAAGDLRSVLITSVLNLERLEVDLFRGQHHWVPATRRLFGGQIVGQALVAAARAVSRDLQAHSLHCYFVRAGDPKVPVLYEVERTRTGKSFSVRSVKAIQHGKPIFICQASFQLAQQSPVQHQFTMPTVPPPEELLTQEELIEKFLQNPNLAERYRKHLNKIQAEDVPIDIKPVNPPDIFCAQPQEPKQFFWVRARGYIGETDMKVHCCVAAYISDYAFLGTALLPHRQYNIKFMVSLDHSMWFHAPFRSDHWMLYECESPWAGGCRGLVHGRLWRRDGVLAVTCTQEGVIRVEENPNQSKL", "length": 376, "header": "tr|A0A8V0YMJ0-1|A0A8V0YMJ0_CHICK Isoform 1 of Acyl-coenzyme A thioesterase 8 OS=Gallus gallus OX=9031 GN=ACOT8 PE=1 SV=1 CANONICAL=A0A8V0YMJ0-1" }, "locus": { "chromosome": "20", "start_pos": 10861173, "end_pos": 10859050, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010038391.1", "url": "https://www.ensembl.org/id/ENSGALT00010038391.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010022199.1", "url": "https://www.ensembl.org/id/ENSGALP00010022199.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "R-GGA-193368", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-193368", "resource": "Reactome", "description": "Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol" }, { "id": "R-GGA-2046106", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2046106", "resource": "Reactome", "description": "alpha-linolenic acid (ALA) metabolism" }, { "id": "R-GGA-389887", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-389887", "resource": "Reactome", "description": "Beta-oxidation of pristanoyl-CoA" }, { "id": "R-GGA-390247", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-390247", "resource": "Reactome", "description": "Beta-oxidation of very long chain fatty acids" }, { "id": "R-GGA-9033241", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9033241", "resource": "Reactome", "description": "Peroxisomal protein import" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 9, "go_terms": [ { "name": "acetyl-CoA hydrolase activity", "id": "GO:0003986", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003986", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMJ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMJ0" } ], "pmid": "" }, { "name": "succinyl-CoA hydrolase activity", "id": "GO:0004778", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004778", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMJ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMJ0" } ], "pmid": "" }, { "name": "choloyl-CoA hydrolase activity", "id": "GO:0033882", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033882", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMJ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMJ0" } ], "pmid": "" }, { "name": "fatty acyl-CoA hydrolase activity", "id": "GO:0047617", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0047617", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMJ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMJ0" } ], "pmid": "" }, { "name": "carboxylic ester hydrolase activity", "id": "GO:0052689", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0052689", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMJ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMJ0" } ], "pmid": "" }, { "name": "medium-chain fatty acyl-CoA hydrolase activity", "id": "GO:0052815", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0052815", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMJ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMJ0" } ], "pmid": "" }, { "name": "long-chain fatty acyl-CoA hydrolase activity", "id": "GO:0052816", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0052816", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMJ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMJ0" } ], "pmid": "" }, { "name": "acetoacetyl-CoA hydrolase activity", "id": "GO:0047603", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0047603", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMJ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMJ0" } ], "pmid": "" }, { "name": "hydroxymethylglutaryl-CoA hydrolase activity", "id": "GO:0047994", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0047994", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMJ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMJ0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "peroxisomal matrix", "id": "GO:0005782", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005782", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMJ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMJ0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "acyl-CoA metabolic process", "id": "GO:0006637", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006637", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMJ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMJ0" } ], "pmid": "" }, { "name": "fatty acid catabolic process", "id": "GO:0009062", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009062", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMJ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMJ0" } ], "pmid": "" }, { "name": "peroxisome fission", "id": "GO:0016559", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016559", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMJ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMJ0" } ], "pmid": "" }, { "name": "dicarboxylic acid catabolic process", "id": "GO:0043649", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043649", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMJ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMJ0" } ], "pmid": "" }, { "name": "fatty acid biosynthetic process", "id": "GO:0006633", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006633", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMJ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMJ0" } ], "pmid": "" }, { "name": "negative regulation of glycoprotein biosynthetic process", "id": "GO:0010561", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010561", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMJ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMJ0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 372, "end_pos": 374, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "11516", "name": "", "equation": "succinyl-CoA + H2O = succinate + CoA + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YMJ0-1" ], "evidence": [ { "id": "11516", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/11516" } ] }, { "id": "14541", "name": "", "equation": "choloyl-CoA + H2O = cholate + CoA + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YMJ0-1" ], "evidence": [ { "id": "14541", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/14541" } ] }, { "id": "15673", "name": "", "equation": "acetoacetyl-CoA + H2O = acetoacetate + CoA + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YMJ0-1" ], "evidence": [ { "id": "15673", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/15673" } ] }, { "id": "16305", "name": "", "equation": "(3S)-3-hydroxy-3-methylglutaryl-CoA + H2O = 3-hydroxy-3-methylglutarate + CoA + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YMJ0-1" ], "evidence": [ { "id": "16305", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/16305" } ] }, { "id": "16645", "name": "", "equation": "hexadecanoyl-CoA + H2O = hexadecanoate + CoA + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q5F336-1", "A0A8V1AEQ0-1", "A0A8V1A396-1", "A0A8V0YR47-1", "A0A8V0YMJ0-1" ], "evidence": [ { "id": "16645", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/16645" } ] }, { "id": "20289", "name": "", "equation": "acetyl-CoA + H2O = acetate + CoA + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1NDD5-1", "A0A8V0YMJ0-1" ], "evidence": [ { "id": "20289", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/20289" } ] }, { "id": "30135", "name": "", "equation": "dodecanoyl-CoA + H2O = dodecanoate + CoA + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q5F336-1", "A0A8V1AEQ0-1", "A0A8V1A396-1", "A0A8V0YMJ0-1" ], "evidence": [ { "id": "30135", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/30135" } ] }, { "id": "30139", "name": "", "equation": "octadecanoyl-CoA + H2O = octadecanoate + CoA + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q5F336-1", "A0A8V0YMJ0-1" ], "evidence": [ { "id": "30139", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/30139" } ] }, { "id": "30143", "name": "", "equation": "octanoyl-CoA + H2O = octanoate + CoA + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V1AEQ0-1", "A0A8V0YMJ0-1" ], "evidence": [ { "id": "30143", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/30143" } ] }, { "id": "31511", "name": "", "equation": "chenodeoxycholoyl-CoA + H2O = chenodeoxycholate + CoA + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YMJ0-1" ], "evidence": [ { "id": "31511", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/31511" } ] }, { "id": "40059", "name": "", "equation": "decanoyl-CoA + H2O = decanoate + CoA + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V1AEQ0-1", "A0A8V0YMJ0-1" ], "evidence": [ { "id": "40059", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/40059" } ] }, { "id": "40103", "name": "", "equation": "propanoyl-CoA + H2O = propanoate + CoA + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YMJ0-1" ], "evidence": [ { "id": "40103", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/40103" } ] }, { "id": "40111", "name": "", "equation": "butanoyl-CoA + H2O = butanoate + CoA + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V1A396-1", "F1NDD5-1", "A0A8V0YMJ0-1" ], "evidence": [ { "id": "40111", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/40111" } ] }, { "id": "40115", "name": "", "equation": "hexanoyl-CoA + H2O = hexanoate + CoA + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1NDD5-1", "A0A8V0YMJ0-1" ], "evidence": [ { "id": "40115", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/40115" } ] }, { "id": "40119", "name": "", "equation": "tetradecanoyl-CoA + H2O = tetradecanoate + CoA + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q5F336-1", "A0A8V1AEQ0-1", "A0A8V1A396-1", "A0A8V0YMJ0-1" ], "evidence": [ { "id": "40119", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/40119" } ] }, { "id": "40131", "name": "", "equation": "(9Z)-hexadecenoyl-CoA + H2O = (9Z)-hexadecenoate + CoA + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YMJ0-1" ], "evidence": [ { "id": "40131", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/40131" } ] }, { "id": "40135", "name": "", "equation": "(9Z)-tetradecenoyl-CoA + H2O = (9Z)-tetradecenoate + CoA + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YMJ0-1" ], "evidence": [ { "id": "40135", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/40135" } ] }, { "id": "40139", "name": "", "equation": "(9Z)-octadecenoyl-CoA + H2O = (9Z)-octadecenoate + CoA + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V1AEQ0-1", "A0A8V0YMJ0-1" ], "evidence": [ { "id": "40139", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/40139" } ] }, { "id": "40143", "name": "", "equation": "(9Z,12Z)-octadecadienoyl-CoA + H2O = (9Z,12Z)-octadecadienoate + CoA + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YMJ0-1" ], "evidence": [ { "id": "40143", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/40143" } ] }, { "id": "40147", "name": "", "equation": "eicosanoyl-CoA + H2O = eicosanoate + CoA + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YMJ0-1" ], "evidence": [ { "id": "40147", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/40147" } ] }, { "id": "40151", "name": "", "equation": "(5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + H2O = (5Z,8Z,11Z,14Z)-eicosatetraenoate + CoA + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V1AEQ0-1", "A0A8V0YMJ0-1" ], "evidence": [ { "id": "40151", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/40151" } ] }, { "id": "40219", "name": "", "equation": "malonyl-CoA + H2O = malonate + CoA + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YMJ0-1" ], "evidence": [ { "id": "40219", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/40219" } ] }, { "id": "40223", "name": "", "equation": "4,8-dimethylnonanoyl-CoA + H2O = 4,8-dimethylnonanoate + CoA + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YMJ0-1" ], "evidence": [ { "id": "40223", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/40223" } ] }, { "id": "40575", "name": "", "equation": "glutaryl-CoA + H2O = glutarate + CoA + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YMJ0-1" ], "evidence": [ { "id": "40575", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/40575" } ] }, { "id": "40583", "name": "", "equation": "hexanedioyl-CoA + H2O = hexanedioate + CoA + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YMJ0-1" ], "evidence": [ { "id": "40583", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/40583" } ] }, { "id": "40587", "name": "", "equation": "octanedioyl-CoA + H2O = octanedioate + CoA + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YMJ0-1" ], "evidence": [ { "id": "40587", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/40587" } ] }, { "id": "40591", "name": "", "equation": "decanedioyl-CoA + H2O = decanedioate + CoA + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YMJ0-1" ], "evidence": [ { "id": "40591", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/40591" } ] }, { "id": "40595", "name": "", "equation": "dodecanedioyl-CoA + H2O = dodecanedioate + CoA + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YMJ0-1" ], "evidence": [ { "id": "40595", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/40595" } ] }, { "id": "59936", "name": "", "equation": "3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oyl-CoA + H2O = 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oate + CoA + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YMJ0-1" ], "evidence": [ { "id": "59936", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/59936" } ] }, { "id": "59940", "name": "", "equation": "2-methyloctadecanoyl-CoA + H2O = 2-methyloctadecanoate + CoA + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YMJ0-1" ], "evidence": [ { "id": "59940", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/59940" } ] }, { "id": "59948", "name": "", "equation": "prostaglandin F2alpha-CoA + H2O = prostaglandin F2alpha + CoA + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YMJ0-1" ], "evidence": [ { "id": "59948", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/59948" } ] }, { "id": "59952", "name": "", "equation": "2,6-dimethylheptanoyl-CoA + H2O = 2,6-dimethylheptanoate + CoA + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YMJ0-1" ], "evidence": [ { "id": "59952", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/59952" } ] }, { "id": "R-GGA-193385", "name": "Hydrolysis of choloyl-CoA to cholate and CoASH", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "peroxisomal matrix", "input_participant_list": [], "output_participant_list": [ "R-ALL-193451" ], "enzyme_list": [ "A0A8V0YMJ0-1" ], "evidence": [ { "id": "R-GGA-193385", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-193385" } ] }, { "id": "R-GGA-2066779", "name": "Conversion of DHA-CoA to docosahexaenoic acid (DHA)", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "peroxisomal matrix", "input_participant_list": [], "output_participant_list": [ "R-ALL-2066763" ], "enzyme_list": [ "A0A8V0YMJ0-1" ], "evidence": [ { "id": "R-GGA-2066779", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2066779" } ] }, { "id": "R-GGA-390304", "name": "acetyl-CoA + H2O => acetate + CoASH + H+", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "peroxisomal matrix", "input_participant_list": [ "R-ALL-353123" ], "output_participant_list": [ "R-ALL-390305" ], "enzyme_list": [ "A0A8V0YMJ0-1" ], "evidence": [ { "id": "R-GGA-390304", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-390304" } ] }, { "id": "R-GGA-5690042", "name": "Peroxisomal ACOT4,6,8 hydrolyse MCFA-CoA, LCFA-CoA", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "peroxisomal matrix", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YMJ0-1" ], "evidence": [ { "id": "R-GGA-5690042", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5690042" } ] }, { "id": "R-GGA-9033235", "name": "Cargo of PEX5S,L translocates from the cytosol to the peroxisomal matrix", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "peroxisomal membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XEK2-1", "A0A8V0XIT0-1", "A0A8V1ANC5-1", "E1BRR7-1", "F1N9G6-1", "A0A8V0YMJ0-1", "A0A1D5P3W4-1", "A0A1L1RJ90-1", "A0A8V0Y1Q3-1", "A0A8V0XXY0-1", "A0A8V0Y2T0-1", "A0A8V1AJL7-1", "F1NKY1-1", "A0A8V0ZLD0-1", "A0A8V0ZPK4-1", "A0A8V1A097-1", "A0A8V0YAP6-1", "A0A8V0ZIT7-1", "A0A8V0ZRI7-1", "A0A8V0ZVL2-1", "F1NG68-1", "A0A8V0ZC97-1", "A0A8V1A124-1", "A0A1D5PZB7-1", "A0A8V1A248-1", "A0A8V1A8Z1-1", "Q5ZL13-1", "A0A8V0ZI42-1", "A0A8V0ZQU7-1" ], "evidence": [ { "id": "R-GGA-9033235", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9033235" } ] }, { "id": "R-GGA-9033236", "name": "PEX5S,L:Cargo binds PEX13:PEX14:PEX2:PEX10:PEX12 (Docking and Translocation Module)", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "peroxisomal membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XEK2-1", "A0A8V0XIT0-1", "A0A8V1ANC5-1", "E1BRR7-1", "F1N9G6-1", "A0A8V0YMJ0-1", "A0A1D5P3W4-1", "A0A1L1RJ90-1", "A0A8V0Y1Q3-1", "A0A8V0XXY0-1", "A0A8V0Y2T0-1", "A0A8V1AJL7-1", "F1NKY1-1", "A0A8V0ZLD0-1", "A0A8V0ZPK4-1", "A0A8V1A097-1", "A0A8V0YAP6-1", "A0A8V0ZIT7-1", "A0A8V0ZRI7-1", "A0A8V0ZVL2-1", "F1NG68-1", "A0A8V0ZC97-1", "A0A8V1A124-1", "A0A1D5PZB7-1", "A0A8V1A248-1", "A0A8V1A8Z1-1", "Q5ZL13-1", "A0A8V0ZI42-1", "A0A8V0ZQU7-1" ], "evidence": [ { "id": "R-GGA-9033236", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9033236" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-193451", "participant_name": "CCA [peroxisomal matrix]", "crossref": [ { "id": "29747", "database": "ChEBI", "url": "" }, { "id": "ZINC000006858022", "database": "ZINC", "url": "" } ] }, { "participant_id": "R-ALL-2066763", "participant_name": "DHA [peroxisomal matrix]", "crossref": [ { "id": "77016", "database": "ChEBI", "url": "" }, { "id": "ZINC000004474564", "database": "ZINC", "url": "" } ] }, { "participant_id": "R-ALL-353123", "participant_name": "Ac-CoA [peroxisomal matrix]", "crossref": [ { "id": "57288", "database": "ChEBI", "url": "" }, { "id": "ZINC000008551095", "database": "ZINC", "url": "" }, { "id": "C00024", "database": "COMPOUND", "url": "" } ] }, { "participant_id": "R-ALL-390305", "participant_name": "CH3COO- [peroxisomal matrix]", "crossref": [ { "id": "30089", "database": "ChEBI", "url": "" }, { "id": "C00033", "database": "COMPOUND", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A0A1D5P3W4", "gene_name": "SLC27A2", "activity": [ { "ec_number": "6.2.1.3", "activity": "a long-chain fatty acid + ATP + CoA = a long-chain fatty acyl-CoA + AMP + diphosphate.", "evidence": [ { "id": "A0A1D5P3W4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P3W4" } ] }, { "ec_number": "6.2.1.3", "activity": "", "evidence": [ { "id": "A0A1D5P3W4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P3W4" } ] } ] }, { "uniprot_ac": "A0A1D5PZB7", "gene_name": "NOS2", "activity": [ { "ec_number": "1.14.13.39", "activity": "2 L-arginine + 3 NADPH + 4 O2 + H(+) = 2 L-citrulline + 2 nitric oxide + 3 NADP(+) + 4 H2O.", "evidence": [ { "id": "A0A1D5PZB7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PZB7" } ] }, { "ec_number": "1.14.13.39", "activity": "", "evidence": [ { "id": "A0A1D5PZB7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PZB7" } ] } ] }, { "uniprot_ac": "A0A1L1RJ90", "gene_name": "HMGCL", "activity": [ { "ec_number": "4.1.3.4", "activity": "(3S)-3-hydroxy-3-methylglutaryl-CoA = acetoacetate + acetyl-CoA.", "evidence": [ { "id": "A0A1L1RJ90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RJ90" } ] }, { "ec_number": "4.1.3.4", "activity": "", "evidence": [ { "id": "A0A1L1RJ90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RJ90" } ] } ] }, { "uniprot_ac": "A0A8V0XEK2", "gene_name": "HACL1", "activity": [ { "ec_number": "4.1.2.63", "activity": "2-hydroxy-3-methylhexadecanoyl-CoA = 2-methylpentadecanal + formyl-CoA.", "evidence": [ { "id": "A0A8V0XEK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEK2" } ] }, { "ec_number": "4.1.2.63", "activity": "", "evidence": [ { "id": "A0A8V0XEK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEK2" } ] } ] }, { "uniprot_ac": "A0A8V0XIT0", "gene_name": "CROT", "activity": [ { "ec_number": "2.3.1.137", "activity": "octanoyl-CoA + (R)-carnitine = O-octanoyl-(R)-carnitine + CoA.", "evidence": [ { "id": "A0A8V0XIT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XIT0" } ] }, { "ec_number": "2.3.1.137", "activity": "", "evidence": [ { "id": "A0A8V0XIT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XIT0" } ] } ] }, { "uniprot_ac": "A0A8V0XXY0", "gene_name": "MLYCD", "activity": [ { "ec_number": "4.1.1.9", "activity": "malonyl-CoA + H(+) = acetyl-CoA + CO2.", "evidence": [ { "id": "A0A8V0XXY0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XXY0" } ] }, { "ec_number": "4.1.1.9", "activity": "", "evidence": [ { "id": "A0A8V0XXY0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XXY0" } ] } ] }, { "uniprot_ac": "A0A8V0Y1Q3", "gene_name": "NUDT7", "activity": [ { "ec_number": "3.6.1.77", "activity": "CoA + H2O = (R)-4'-phosphopantetheine + adenosine 3',5'-bisphosphate + 2 H(+).", "evidence": [ { "id": "A0A8V0Y1Q3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y1Q3" } ] }, { "ec_number": "3.6.1.77", "activity": "", "evidence": [ { "id": "A0A8V0Y1Q3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y1Q3" } ] } ] }, { "uniprot_ac": "A0A8V0Y2T0", "gene_name": "ECH1", "activity": [ { "ec_number": "5.3.3.21", "activity": "a (3E,5Z)-dienoyl-CoA = a (2E,4E)-(5,6-saturated)-dienoyl-CoA.", "evidence": [ { "id": "A0A8V0Y2T0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2T0" } ] }, { "ec_number": "5.3.3.21", "activity": "", "evidence": [ { "id": "A0A8V0Y2T0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2T0" } ] } ] }, { "uniprot_ac": "A0A8V0YAP6", "gene_name": "GNPAT", "activity": [ { "ec_number": "2.3.1.42", "activity": "dihydroxyacetone phosphate + an acyl-CoA = a 1-acylglycerone 3-phosphate + CoA.", "evidence": [ { "id": "A0A8V0YAP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAP6" } ] }, { "ec_number": "2.3.1.42", "activity": "", "evidence": [ { "id": "A0A8V0YAP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAP6" } ] } ] }, { "uniprot_ac": "A0A8V0YMJ0", "gene_name": "ACOT8", "activity": [ { "ec_number": "3.1.2.2", "activity": "hexadecanoyl-CoA + H2O = hexadecanoate + CoA + H(+).", "evidence": [ { "id": "A0A8V0YMJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMJ0" } ] }, { "ec_number": "3.1.2.27", "activity": "(3S)-3-hydroxy-3-methylglutaryl-CoA + H2O = 3-hydroxy-3-methylglutarate + CoA + H(+).", "evidence": [ { "id": "A0A8V0YMJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMJ0" } ] }, { "ec_number": "3.1.2.1", "activity": "acetyl-CoA + H2O = acetate + CoA + H(+).", "evidence": [ { "id": "A0A8V0YMJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMJ0" } ] }, { "ec_number": "3.1.2.11", "activity": "acetoacetyl-CoA + H2O = acetoacetate + CoA + H(+).", "evidence": [ { "id": "A0A8V0YMJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMJ0" } ] }, { "ec_number": "3.1.2.3", "activity": "succinyl-CoA + H2O = succinate + CoA + H(+).", "evidence": [ { "id": "A0A8V0YMJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMJ0" } ] }, { "ec_number": "3.1.2.5", "activity": "(3S)-3-hydroxy-3-methylglutaryl-CoA + H2O = 3-hydroxy-3-methylglutarate + CoA + H(+).", "evidence": [ { "id": "A0A8V0YMJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMJ0" } ] }, { "ec_number": "3.1.2.1", "activity": "", "evidence": [ { "id": "A0A8V0YMJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMJ0" } ] }, { "ec_number": "3.1.2.3", "activity": "", "evidence": [ { "id": "A0A8V0YMJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMJ0" } ] }, { "ec_number": "3.1.2.2", "activity": "", "evidence": [ { "id": "A0A8V0YMJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMJ0" } ] }, { "ec_number": "3.1.2.11", "activity": "", "evidence": [ { "id": "A0A8V0YMJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMJ0" } ] }, { "ec_number": "3.1.2.5", "activity": "", "evidence": [ { "id": "A0A8V0YMJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMJ0" } ] }, { "ec_number": "3.1.2.27", "activity": "", "evidence": [ { "id": "A0A8V0YMJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMJ0" } ] } ] }, { "uniprot_ac": "A0A8V0YR47", "gene_name": "PPT1", "activity": [ { "ec_number": "3.1.2.22", "activity": "S-hexadecanoyl-L-cysteinyl-[protein] + H2O = L-cysteinyl-[protein] + hexadecanoate + H(+).", "evidence": [ { "id": "A0A8V0YR47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YR47" } ] }, { "ec_number": "3.1.2.2", "activity": "hexadecanoyl-CoA + H2O = hexadecanoate + CoA + H(+).", "evidence": [ { "id": "A0A8V0YR47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YR47" } ] }, { "ec_number": "3.1.2.22", "activity": "", "evidence": [ { "id": "A0A8V0YR47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YR47" } ] }, { "ec_number": "3.1.2.2", "activity": "", "evidence": [ { "id": "A0A8V0YR47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YR47" } ] } ] }, { "uniprot_ac": "A0A8V0ZC97", "gene_name": "PEX10", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZC97", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC97" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0ZC97", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC97" } ] } ] }, { "uniprot_ac": "A0A8V0ZI42", "gene_name": "IDE", "activity": [ { "ec_number": "3.4.24.56", "activity": "Degradation of insulin, glucagon and other polypeptides. No action on proteins.", "evidence": [ { "id": "A0A8V0ZI42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI42" } ] }, { "ec_number": "3.4.24.56", "activity": "", "evidence": [ { "id": "A0A8V0ZI42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI42" } ] } ] }, { "uniprot_ac": "A0A8V0ZIT7", "gene_name": "PECR", "activity": [ { "ec_number": "1.3.1.38", "activity": "a (2E)-enoyl-CoA + NADPH + H(+) = a 2,3-saturated acyl-CoA + NADP(+).", "evidence": [ { "id": "A0A8V0ZIT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIT7" } ] }, { "ec_number": "1.3.1.38", "activity": "", "evidence": [ { "id": "A0A8V0ZIT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIT7" } ] } ] }, { "uniprot_ac": "A0A8V0ZLD0", "gene_name": "TYSND1", "activity": [ { "ec_number": "3.4.21.-", "activity": "", "evidence": [ { "id": "A0A8V0ZLD0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLD0" } ] } ] }, { "uniprot_ac": "A0A8V0ZPK4", "gene_name": "IDH1", "activity": [ { "ec_number": "1.1.1.42", "activity": "D-threo-isocitrate + NADP(+) = 2-oxoglutarate + CO2 + NADPH.", "evidence": [ { "id": "A0A8V0ZPK4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPK4" } ] }, { "ec_number": "1.1.1.42", "activity": "", "evidence": [ { "id": "A0A8V0ZPK4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPK4" } ] } ] }, { "uniprot_ac": "A0A8V0ZQU7", "gene_name": "PAOX", "activity": [ { "ec_number": "1.5.3.13", "activity": "N(1)-acetylspermine + O2 + H2O = 3-acetamidopropanal + spermidine + H2O2.", "evidence": [ { "id": "A0A8V0ZQU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQU7" } ] }, { "ec_number": "1.5.3.13", "activity": "", "evidence": [ { "id": "A0A8V0ZQU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQU7" } ] } ] }, { "uniprot_ac": "A0A8V0ZRI7", "gene_name": "LONP2", "activity": [ { "ec_number": "3.4.21.-", "activity": "", "evidence": [ { "id": "A0A8V0ZRI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRI7" } ] } ] }, { "uniprot_ac": "A0A8V0ZVL2", "gene_name": "CAT", "activity": [ { "ec_number": "1.11.1.6", "activity": "2 H2O2 = O2 + 2 H2O.", "evidence": [ { "id": "A0A8V0ZVL2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVL2" } ] }, { "ec_number": "1.11.1.6", "activity": "", "evidence": [ { "id": "A0A8V0ZVL2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVL2" } ] } ] }, { "uniprot_ac": "A0A8V1A097", "gene_name": "HAO2", "activity": [ { "ec_number": "1.1.3.15", "activity": "glycolate + O2 = glyoxylate + H2O2.", "evidence": [ { "id": "A0A8V1A097", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A097" } ] }, { "ec_number": "1.1.3.15", "activity": "", "evidence": [ { "id": "A0A8V1A097", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A097" } ] } ] }, { "uniprot_ac": "A0A8V1A124", "gene_name": "AGXT", "activity": [ { "ec_number": "2.6.1.51", "activity": "L-serine + pyruvate = 3-hydroxypyruvate + L-alanine.", "evidence": [ { "id": "A0A8V1A124", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A124" } ] }, { "ec_number": "2.6.1.44", "activity": "2-oxobutanoate + L-alanine = (2S)-2-aminobutanoate + pyruvate.", "evidence": [ { "id": "A0A8V1A124", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A124" } ] }, { "ec_number": "2.6.1.44", "activity": "", "evidence": [ { "id": "A0A8V1A124", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A124" } ] }, { "ec_number": "2.6.1.51", "activity": "", "evidence": [ { "id": "A0A8V1A124", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A124" } ] } ] }, { "uniprot_ac": "A0A8V1A248", "gene_name": "EHHADH", "activity": [ { "ec_number": "1.1.1.35", "activity": "a (3S)-3-hydroxyacyl-CoA + NAD(+) = a 3-oxoacyl-CoA + NADH + H(+).", "evidence": [ { "id": "A0A8V1A248", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A248" } ] }, { "ec_number": "4.2.1.17", "activity": "(3S)-3-hydroxyadipyl-CoA = (E)-2,3-didehydroadipoyl-CoA + H2O.", "evidence": [ { "id": "A0A8V1A248", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A248" } ] }, { "ec_number": "5.3.3.8", "activity": "a (3Z)-enoyl-CoA = a 4-saturated (2E)-enoyl-CoA.", "evidence": [ { "id": "A0A8V1A248", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A248" } ] }, { "ec_number": "5.3.3.8", "activity": "", "evidence": [ { "id": "A0A8V1A248", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A248" } ] }, { "ec_number": "4.2.1.17", "activity": "", "evidence": [ { "id": "A0A8V1A248", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A248" } ] }, { "ec_number": "1.1.1.35", "activity": "", "evidence": [ { "id": "A0A8V1A248", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A248" } ] } ] }, { "uniprot_ac": "A0A8V1A396", "gene_name": "ACOT11", "activity": [ { "ec_number": "3.1.2.2", "activity": "hexadecanoyl-CoA + H2O = hexadecanoate + CoA + H(+).", "evidence": [ { "id": "A0A8V1A396", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A396" } ] }, { "ec_number": "3.1.2.2", "activity": "", "evidence": [ { "id": "A0A8V1A396", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A396" } ] } ] }, { "uniprot_ac": "A0A8V1A8Z1", "gene_name": "SCP2", "activity": [ { "ec_number": "2.3.1.176", "activity": "4,8,12-trimethyltridecanoyl-CoA + propanoyl-CoA = 3-oxopristanoyl-CoA + CoA.", "evidence": [ { "id": "A0A8V1A8Z1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8Z1" } ] }, { "ec_number": "2.3.1.16", "activity": "an acyl-CoA + acetyl-CoA = a 3-oxoacyl-CoA + CoA.", "evidence": [ { "id": "A0A8V1A8Z1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8Z1" } ] }, { "ec_number": "2.3.1.155", "activity": "tetradecanoyl-CoA + acetyl-CoA = 3-oxohexadecanoyl-CoA + CoA.", "evidence": [ { "id": "A0A8V1A8Z1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8Z1" } ] }, { "ec_number": "2.3.1.16", "activity": "", "evidence": [ { "id": "A0A8V1A8Z1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8Z1" } ] }, { "ec_number": "2.3.1.155", "activity": "", "evidence": [ { "id": "A0A8V1A8Z1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8Z1" } ] }, { "ec_number": "2.3.1.176", "activity": "", "evidence": [ { "id": "A0A8V1A8Z1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8Z1" } ] } ] }, { "uniprot_ac": "A0A8V1AEQ0", "gene_name": "THEM4", "activity": [ { "ec_number": "3.1.2.2", "activity": "hexadecanoyl-CoA + H2O = hexadecanoate + CoA + H(+).", "evidence": [ { "id": "A0A8V1AEQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEQ0" } ] }, { "ec_number": "3.1.2.2", "activity": "", "evidence": [ { "id": "A0A8V1AEQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEQ0" } ] } ] }, { "uniprot_ac": "A0A8V1AJL7", "gene_name": "CRAT", "activity": [ { "ec_number": "2.3.1.137", "activity": "octanoyl-CoA + (R)-carnitine = O-octanoyl-(R)-carnitine + CoA.", "evidence": [ { "id": "A0A8V1AJL7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJL7" } ] }, { "ec_number": "2.3.1.7", "activity": "(R)-carnitine + acetyl-CoA = O-acetyl-(R)-carnitine + CoA.", "evidence": [ { "id": "A0A8V1AJL7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJL7" } ] }, { "ec_number": "2.3.1.137", "activity": "", "evidence": [ { "id": "A0A8V1AJL7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJL7" } ] }, { "ec_number": "2.3.1.7", "activity": "", "evidence": [ { "id": "A0A8V1AJL7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJL7" } ] } ] }, { "uniprot_ac": "A0A8V1ANC5", "gene_name": "PIPOX", "activity": [ { "ec_number": "1.5.3.1", "activity": "sarcosine + O2 + H2O = formaldehyde + glycine + H2O2.", "evidence": [ { "id": "A0A8V1ANC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANC5" } ] }, { "ec_number": "1.5.3.7", "activity": "L-pipecolate + O2 = L-1-piperideine-6-carboxylate + H2O2 + H(+).", "evidence": [ { "id": "A0A8V1ANC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANC5" } ] }, { "ec_number": "1.5.3.7", "activity": "", "evidence": [ { "id": "A0A8V1ANC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANC5" } ] }, { "ec_number": "1.5.3.1", "activity": "", "evidence": [ { "id": "A0A8V1ANC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANC5" } ] } ] }, { "uniprot_ac": "E1BRR7", "gene_name": "HAO1", "activity": [ { "ec_number": "1.1.3.15", "activity": "glycolate + O2 = glyoxylate + H2O2.", "evidence": [ { "id": "E1BRR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BRR7" } ] }, { "ec_number": "1.1.3.15", "activity": "", "evidence": [ { "id": "E1BRR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BRR7" } ] } ] }, { "uniprot_ac": "F1N9G6", "gene_name": "GSTK1", "activity": [ { "ec_number": "2.5.1.18", "activity": "RX + glutathione = an S-substituted glutathione + a halide anion + H(+).", "evidence": [ { "id": "F1N9G6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N9G6" } ] }, { "ec_number": "2.5.1.18", "activity": "", "evidence": [ { "id": "F1N9G6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N9G6" } ] } ] }, { "uniprot_ac": "F1NDD5", "gene_name": "ACOT12", "activity": [ { "ec_number": "3.1.2.1", "activity": "acetyl-CoA + H2O = acetate + CoA + H(+).", "evidence": [ { "id": "F1NDD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NDD5" } ] }, { "ec_number": "3.1.2.1", "activity": "", "evidence": [ { "id": "F1NDD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NDD5" } ] } ] }, { "uniprot_ac": "F1NG68", "gene_name": "DECR2", "activity": [ { "ec_number": "1.3.1.124", "activity": "a (2E,4E)-dienoyl-CoA + NADPH + H(+) = a 4,5-saturated-(3E)-enoyl-CoA + NADP(+).", "evidence": [ { "id": "F1NG68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NG68" } ] }, { "ec_number": "1.3.1.124", "activity": "", "evidence": [ { "id": "F1NG68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NG68" } ] } ] }, { "uniprot_ac": "F1NKY1", "gene_name": "AMACR", "activity": [ { "ec_number": "5.1.99.4", "activity": "a (2S)-2-methylacyl-CoA = a (2R)-2-methylacyl-CoA.", "evidence": [ { "id": "F1NKY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NKY1" } ] }, { "ec_number": "5.1.99.4", "activity": "", "evidence": [ { "id": "F1NKY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NKY1" } ] } ] }, { "uniprot_ac": "Q5F336", "gene_name": "MBLAC2", "activity": [ { "ec_number": "3.1.2.2", "activity": "hexadecanoyl-CoA + H2O = hexadecanoate + CoA + H(+).", "evidence": [ { "id": "Q5F336", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F336" } ] }, { "ec_number": "3.5.2.6", "activity": "a beta-lactam + H2O = a substituted beta-amino acid.", "evidence": [ { "id": "Q5F336", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F336" } ] }, { "ec_number": "3.1.2.2", "activity": "", "evidence": [ { "id": "Q5F336", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F336" } ] } ] }, { "uniprot_ac": "Q5ZL13", "gene_name": "NUDT19", "activity": [ { "ec_number": "3.6.1.-", "activity": "", "evidence": [ { "id": "Q5ZL13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZL13" } ] }, { "ec_number": "3.6.1.77", "activity": "CoA + H2O = (R)-4'-phosphopantetheine + adenosine 3',5'-bisphosphate + 2 H(+).", "evidence": [ { "id": "Q5ZL13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZL13" } ] }, { "ec_number": "3.6.1.77", "activity": "", "evidence": [ { "id": "Q5ZL13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZL13" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YMJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMJ0" }, { "id": "PF02551", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02551" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Acyl-CoA thioesterase 2 C-terminal", "eco_id": "ECO_0000259", "start_pos": 259, "end_pos": 364, "start_aa": "Gln", "end_aa": "Val", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0YMJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMJ0" }, { "id": "PF13622", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13622" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Acyl-CoA thioesterase-like N-terminal HotDog", "eco_id": "ECO_0000259", "start_pos": 105, "end_pos": 187, "start_aa": "Trp", "end_aa": "Gln", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "3.1.2.2", "ec_name": "hexadecanoyl-CoA + H2O = hexadecanoate + CoA + H(+).", "evidence": [ { "id": "3.1.2.2", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.2.2" }, { "id": "3.1.2.2", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=3.1.2.2" } ] }, { "ec_number": "3.1.2.27", "ec_name": "(3S)-3-hydroxy-3-methylglutaryl-CoA + H2O = 3-hydroxy-3-methylglutarate + CoA + H(+).", "evidence": [ { "id": "3.1.2.27", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.2.27" }, { "id": "3.1.2.27", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=3.1.2.27" } ] }, { "ec_number": "3.1.2.1", "ec_name": "acetyl-CoA + H2O = acetate + CoA + H(+).", "evidence": [ { "id": "3.1.2.1", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.2.1" }, { "id": "3.1.2.1", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=3.1.2.1" } ] }, { "ec_number": "3.1.2.11", "ec_name": "acetoacetyl-CoA + H2O = acetoacetate + CoA + H(+).", "evidence": [ { "id": "3.1.2.11", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.2.11" } ] }, { "ec_number": "3.1.2.3", "ec_name": "succinyl-CoA + H2O = succinate + CoA + H(+).", "evidence": [ { "id": "3.1.2.3", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.2.3" } ] }, { "ec_number": "3.1.2.5", "ec_name": "(3S)-3-hydroxy-3-methylglutaryl-CoA + H2O = 3-hydroxy-3-methylglutarate + CoA + H(+).", "evidence": [ { "id": "3.1.2.5", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.2.5" } ] } ], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 372, "end_pos": 374 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YMJ4-1", "uniprot_ac": "A0A8V0YMJ4", "uniprot_id": "A0A8V0YMJ4_CHICK", "mass": { "chemical_mass": 80484.0, "monoisotopic_mass": 80484.0 }, "refseq": {}, "gene_names": [ { "name": "RPAP3", "type": "recommended", "evidence": [ { "id": "A0A8V0YMJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMJ4" } ] } ], "protein_names": [ { "name": "RNA polymerase II-associated protein 3", "type": "recommended", "evidence": [ { "id": "A0A8V0YMJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMJ4/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMJ4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMJ4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RPAP3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMJ4", "locus": { "chromosome": "1", "start_pos": 31568897, "end_pos": 31583839, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010014134", "url": "https://www.ensembl.org/id/ENSGALG00010014134" } ] } } ], "crossref": [ { "id": "A0A8V0YMJ4", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YMJ4", "database": "AlphaFoldDB", "categories": [] }, { "id": "417811", "url": "https://www.ncbi.nlm.nih.gov/gene/417811", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011990", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011990", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019734", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019734", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR025986", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025986", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051966", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051966", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "NFTPDRP", "url": "https://omabrowser.org/oma/group/NFTPDRP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YMJ4", "url": "https://www.orthodb.org/?gene=A0A8V0YMJ4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YMU2", "url": "https://www.orthodb.org/?gene=A0A8V0YMU2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46423", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46423", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46423:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46423:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00515", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00515", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13181", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13181", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13432", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13432", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13877", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13877", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YMJ4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMJ4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YMJ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMJ4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YMU2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMU2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YMU2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMU2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRHLLPRSRRRALQPGRRSGCAAASGAGEAETGSGVMAGRDGITMTASNKALELQLQMKQNAEELQDFMRELESWEKDIKEVDSELRKQSGVSEENLPPIRNKTFKKKKKSKTKVPSKTTTEENKKNKIKSYDYEAWGKLDVDKILEELDKDDSTHDSVSPESDSEEDGIHVDKEKALAEKEKGNKYFKQGNFDEAIKCYTRGMHSDPFNPVLPTNRASAFYRMKKFSVAESDCNLALALDKNYTKAYARRGAARFALKNFQGAKEDYEKVLELDANNYEAKNELKKIEQALSSESSEQKEFEEAVRSELTENERRCIEEEQLKQKAVTEKDLGNGYFKEGKYEAAIECYTRGIAADGTNALLPANRAMAYLKIQKYEEAENDCTQALLLDASYSKAFARRGAARVALGKLKEAMQDFEAVLKLEPGNKQAINELTKIRNELAEKEQSCHEEYPAVLIKESEIKNIVKLTHNPLNLKSTKPLRRIAVEEVDDDVLNSDFSSSTSLVNNWKNSVNIETTENLDQDDQLTSMDIPKAKQLKIEEITDVSSPQLPAGAKGVSSVLHPSMNKQIERENKASFRSASPVPAIPANSFQLESDFRKLKDCPEKMYLYLKQIEPSIYPKLFQKSLDPDLFNQILRILHDFYIEKEEPSLILEILQRLSELKRFDMAVMFMSGSEKKITQVLFSHMKHMGLKDTSVEQLEKKYAVFS", "length": 709, "header": "tr|A0A8V0YMJ4-1|A0A8V0YMJ4_CHICK Isoform 1 of RNA polymerase II-associated protein 3 OS=Gallus gallus OX=9031 GN=RPAP3 PE=3 SV=1 CANONICAL=A0A8V0YMJ4-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YMJ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMJ4/entry#A0A8V0YMJ4-1", "sequence": { "sequence": "MRHLLPRSRRRALQPGRRSGCAAASGAGEAETGSGVMAGRDGITMTASNKALELQLQMKQNAEELQDFMRELESWEKDIKEVDSELRKQSGVSEENLPPIRNKTFKKKKKSKTKVPSKTTTEENKKNKIKSYDYEAWGKLDVDKILEELDKDDSTHDSVSPESDSEEDGIHVDKEKALAEKEKGNKYFKQGNFDEAIKCYTRGMHSDPFNPVLPTNRASAFYRMKKFSVAESDCNLALALDKNYTKAYARRGAARFALKNFQGAKEDYEKVLELDANNYEAKNELKKIEQALSSESSEQKEFEEAVRSELTENERRCIEEEQLKQKAVTEKDLGNGYFKEGKYEAAIECYTRGIAADGTNALLPANRAMAYLKIQKYEEAENDCTQALLLDASYSKAFARRGAARVALGKLKEAMQDFEAVLKLEPGNKQAINELTKIRNELAEKEQSCHEEYPAVLIKESEIKNIVKLTHNPLNLKSTKPLRRIAVEEVDDDVLNSDFSSSTSLVNNWKNSVNIETTENLDQDDQLTSMDIPKAKQLKIEEITDVSSPQLPAGAKGVSSVLHPSMNKQIERENKASFRSASPVPAIPANSFQLESDFRKLKDCPEKMYLYLKQIEPSIYPKLFQKSLDPDLFNQILRILHDFYIEKEEPSLILEILQRLSELKRFDMAVMFMSGSEKKITQVLFSHMKHMGLKDTSVEQLEKKYAVFS", "length": 709, "header": "tr|A0A8V0YMJ4-1|A0A8V0YMJ4_CHICK Isoform 1 of RNA polymerase II-associated protein 3 OS=Gallus gallus OX=9031 GN=RPAP3 PE=3 SV=1 CANONICAL=A0A8V0YMJ4-1" }, "locus": { "chromosome": "1", "start_pos": 31583831, "end_pos": 31569311, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033951.1", "url": "https://www.ensembl.org/id/ENSGALT00010033951.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019953.1", "url": "https://www.ensembl.org/id/ENSGALP00010019953.1" } ] } }, { "isoform_ac": "A0A8V0YMU2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMJ4/entry#A0A8V0YMU2-1", "sequence": { "sequence": "MTASNKALELQLQMKQNAEELQDFMRELESWEKDIKEVDSELRKQSGVSEENLPPIRNKTFKKKKKSKTKVPSKTTTEENKKNKIKSYDYEAWGKLDVDKILEELDKDDSTHDSVSPESDSEEDGIHVDKEKALAEKEKGNKYFKQGNFDEAIKCYTRGMHSDPFNPVLPTNRASAFYRMKKFSVAESDCNLALALDKNYTKAYARRGAARFALKNFQGAKEDYEKVLELDANNYEAKNELKKIEQALSSESSEQKEFEEAVRSELTENERRCIEEEQLKQKAVTEKDLGNGYFKEGKYEAAIECYTRGIAADGTNALLPANRAMAYLKIQKYEEAENDCTQALLLDASYSKAFARRGAARVALGKLKEAMQDFEAVLKLEPGNKQAINELTKIRNELAEKEQSCHEEYPAVLIKESEIKNIVKLTHNPLNLKSTKPLRRIAVEEVDDDVLNSDFSSSTSLVNNWKNSVNIETTENLDQDDQLTSMDIPKAKQLKIEEITDVSSPQLPAGAKGVSSVLHPSMNKQIERENKASFRSASPVPAIPANSFQLESDFRKLKDCPEKMYLYLKQIEPSIYPKLFQKSLDPDLFNQILRILHDFYIEKEEPSLILEILQRLSELKRFDMAVMFMSGSEKKI", "length": 636, "header": "tr|A0A8V0YMU2-1|A0A8V0YMU2_CHICK Computationally mapped isoform of RNA polymerase II-associated protein 3 OS=Gallus gallus OX=9031 GN=RPAP3 PE=3 SV=1 CANONICAL=A0A8V0YMJ4-1" }, "locus": { "chromosome": "1", "start_pos": 31582901, "end_pos": 31569912, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033944.1", "url": "https://www.ensembl.org/id/ENSGALT00010033944.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019951.1", "url": "https://www.ensembl.org/id/ENSGALP00010019951.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "F1R498-1", "protein_name": "RNA polymerase II-associated protein 3", "gene_name": "rpap3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSGNKALELQIQMRHNAEDLQSFMRDLDSWEDEIKQKDQQLRSENTGDTQKTLPPVRNKDYKKTKKRAKRQTNSLKEQKETQRIKSYDYQTWDKFDVEKALESMDAEESPVQSNESDSECVNVDRDLALAEKEKGNQFFKDGRFDSAIECYTKAMDADPYNPVPPTNRATCFYRLKKFAVAESDCNLAIALDSKYVKAYIRRAATRTALQKHREALEDYEMVLKLDPGNSEAQTEVQKLQQELNSSKQTEETEEKRESITEPTAEQQQRLQEQQRKQEAVMHKDRGNAYFKEGRYEVAVESYTRGMEADETNALLPANRAMAFLKLNRFAEAEQDCSAALALDPSYTKAFARRATARAALGKCRDARDDFEQVLKLEPGNKQAISEIEKLTAEMRSSLAPQEDTLRKTVQPIHKPEHLRSTKPLRRMEIEEVGGAIAQTPLTSSPHHKIQKMEEKPDASCPAVARSAEDEVIPPPPCTSFQLEADLRKISHNPQSTYSYLKQISPDSYPKIFQNSLESDVLNRILQTFHRCHTRPEEASLLLDVLRNLASVKRFDMAVMFMSNTEKKMVQELFERIHNAGLTDSTVQDLQKKYGL", "length": 595 }, "evidence": [ { "id": "A0A8V0YMJ4", "url": "https://omabrowser.org/oma/group/A0A8V0YMJ4/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q68FQ7-1", "protein_name": "RNA polymerase II-associated protein 3", "gene_name": "Rpap3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTSTSKAVELQLQVKHNAEELQDFMRDLEHWEKTMRQKDLELRRQSGVPEENLPPIRNGSFRKKKKRKTKDSSKKTKEENTKNRIKSFDYDAWAKLDVDSILDELDKEDSTHDSVSQESESDEDGVRVDSQKALVLKEKGNKYFKQGKYDEAIECYTKGMDADPYNPVLPTNRASAYFRLKKFAVAESDCNLAIALSRSYTKAYARRGAARFALQKLEDARKDYVKVLELEPDNFEATNELRKIDQALTSKENSHPKDIAAVIKPAEGERKANEDQRGRQKAIAEKDLGNGFFKEGKYEQAIECYTRGIAADSTNALLPANRAMAYLKVQKYEEAERDCTQAILLDGSYSKAFARRGTARTFLGKINEAKQDFETVLLLEPGNKQAVTELSRIKKELIEKGRWDDVFLDSTQRHNVVKPVDSPHRGSPKALKKVFIEETGNLIESVDAPESSATVPESDRAAVAVDTGRKKDFSQGDSVSSGETPRAKVLKIEAVGDSSAPQAQVDVKQGVRQSVSEKTSVRVAQTPGQLAAVVLPPVPANSFQLESDFRQLRSSPEMLYQYVKKIEPSLYPKLFQKNLDPDVFNQIIKILHDFYVEREKPALIFEVLERLSQLRRFDMAVMFMSGTERELTKVLFNHLEKSELKEDSVEELKKRYGGG", "length": 659 }, "evidence": [ { "id": "A0A8V0YMJ4", "url": "https://omabrowser.org/oma/group/A0A8V0YMJ4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9D706-1", "protein_name": "RNA polymerase II-associated protein 3", "gene_name": "Rpap3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTSASKAVELQLQVKHNAEELQDFMRDLEHWEKDMKEKDLELRRQGGVAEENLPPIRNGNFRKKKKKGKAKESSRKTKEENTKNRIKSYDYDAWAKLDVDRILDELDKEDSTHDSLSQESESDEDGIRVDSQKALVLKEKGNKYFKQGKYDEAIECYTKGMDADPYNPVLPTNRASAYFRLKKFAVAESDCNLAIALSRTYTKAYARRGAARFALQKLEDARKDYEKVLELEPDNFEATNELRKINQALTSKENSGPGAAAAAESKPAAGESKPTGGQQGRQKAIAEKDLGNGFFKEGKYEQAIECYTRGIAADRTNALLPANRAMAYLKIQRYEEAERDCTQAIVLDGSYSKAFARRGTARTFLGKINEAKQDFETVLLLEPGNKQAATELSRIKKELIEKGHWDDVFLDSTQRHHVVKAVDNPPRGSPKALKKVFIEETGNLIETVDAPDSSATVPESDRATAAVGTGTKKNPSEGVSLPAGDRPRAKVLKIEAVSDTSAPQAQVGVKQDARQPGSEKASVRAEQMPGQLAAAGLPPVPANSFQLESDFRQLRSSPEMLYQYVKNIEPSLYPKLFQKNLDPDVFNQIIKILHDFYIEREKPALIFEVLERLSQLRRFDMAVMFMSGPERKLTNVLFNHLEKSDLKEDSVEELKKRYGG", "length": 660 }, "evidence": [ { "id": "A0A8V0YMJ4", "url": "https://omabrowser.org/oma/group/A0A8V0YMJ4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9H6T3-1", "protein_name": "RNA polymerase II-associated protein 3", "gene_name": "RPAP3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTSANKAIELQLQVKQNAEELQDFMRDLENWEKDIKQKDMELRRQNGVPEENLPPIRNGNFRKKKKGKAKESSKKTREENTKNRIKSYDYEAWAKLDVDRILDELDKDDSTHESLSQESESEEDGIHVDSQKALVLKEKGNKYFKQGKYDEAIDCYTKGMDADPYNPVLPTNRASAYFRLKKFAVAESDCNLAVALNRSYTKAYSRRGAARFALQKLEEAKKDYERVLELEPNNFEATNELRKISQALASKENSYPKEADIVIKSTEGERKQIEAQQNKQQAISEKDRGNGFFKEGKYERAIECYTRGIAADGANALLPANRAMAYLKIQKYEEAEKDCTQAILLDGSYSKAFARRGTARTFLGKLNEAKQDFETVLLLEPGNKQAVTELSKIKKELIEKGHWDDVFLDSTQRQNVVKPIDNPPHPGSTKPLKKVIIEETGNLIQTIDVPDSTTAAAPENNPINLANVIAATGTTSKKNSSQDDLFPTSDTPRAKVLKIEEVSDTSSLQPQASLKQDVCQSYSEKMPIEIEQKPAQFATTVLPPIPANSFQLESDFRQLKSSPDMLYQYLKQIEPSLYPKLFQKNLDPDVFNQIVKILHDFYIEKEKPLLIFEILQRLSELKRFDMAVMFMSETEKKIARALFNHIDKSGLKDSSVEELKKRYGG", "length": 665 }, "evidence": [ { "id": "A0A8V0YMJ4", "url": "https://omabrowser.org/oma/group/A0A8V0YMJ4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9V3E9-1", "protein_name": "RNA polymerase II-associated protein 3", "gene_name": "spag", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSAQEKAFELQRQVRQNAREYENSVKDLYSWEQDIKNKEKELQKSPLSAANKDLPVRSHVQTDKSRKESPSSSAASSPTEKQDLPVDPVAQQYKKANDIKDRGNTYVKQGEYEKAIVAYSTAIAVYPHDPIYHINRALCYLKQESFDQCVEDCEAAIALDKLCVKAYYRRMQANESLGNNMEALKDCTTVLAIEPKNIEAKRSLARINDRLRKIATKSGPNFTPDRPGMIEILPIEKPAYKRSKKAMRSVPVVDVVSPRATIDDSNQLRISDEDIDKIFNSNCGIIEEVKKTNPKPTPMPDTSGPPKAETIAKTSKEVKPTKQTAVKVAPAVETPKETETRKDTKIVPESDNEAKPSAPKKTAVEVPKVQTQVSPPKTTIERSPEVNTVQTEKIEQASSNNAMSPSPIERFLPPAPTSTAQFHVTWKELSGPQKYQYLKSIEVPNLCKILGAGFDSDTFADLLRTIHDFFVPNKEPNTAAVLLEISKNDEFTILAMLMSAEEKKMVSSILNAIKNWPSKNPAVLDNLFKEYGVA", "length": 534 }, "evidence": [ { "id": "A0A8V0YMJ4", "url": "https://omabrowser.org/oma/group/A0A8V0YMJ4/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "R2TP complex", "id": "GO:0097255", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097255", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMJ4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMJ4" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMJ4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMJ4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 102, "end_pos": 104, "annotation": "n_glycosylation_sequon" }, { "start_pos": 243, "end_pos": 245, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YMJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMJ4" }, { "id": "PF13877", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13877" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RNA-polymerase II-associated protein 3-like C-terminal", "eco_id": "ECO_0000259", "start_pos": 588, "end_pos": 678, "start_aa": "Pro", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 102, "end_pos": 104 }, { "start_pos": 243, "end_pos": 245 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YMK5-1", "uniprot_ac": "A0A8V0YMK5", "uniprot_id": "A0A8V0YMK5_CHICK", "mass": { "chemical_mass": 77429.0, "monoisotopic_mass": 77429.0 }, "refseq": { "ac": "XP_015144116", "name": "SUN domain-containing protein 2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015144116" }, "gene_names": [ { "name": "SUN2", "type": "recommended", "evidence": [ { "id": "A0A8V0YMK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMK5" } ] }, { "name": "SUN2", "type": "synonym", "evidence": [ { "id": "XP_015144116", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015144116" } ] } ], "protein_names": [ { "name": "SUN domain-containing protein 2", "type": "synonym", "evidence": [ { "id": "XP_015144116", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015144116" } ] }, { "name": "Sad1 and UNC84 domain containing 2", "type": "synonym", "evidence": [ { "id": "A0A8V0YMK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMK5/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015144116.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015144116", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015144116" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMK5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMK5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SUN2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMK5", "locus": { "chromosome": "1", "start_pos": 50855566, "end_pos": 50848541, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010015939", "url": "https://www.ensembl.org/id/ENSGALG00010015939" } ] } } ], "crossref": [ { "id": "A0A8V0YMK5", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YMK5", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd21438", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd21438", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "418021", "url": "https://www.ncbi.nlm.nih.gov/gene/418021", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR012919", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012919", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040994", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040994", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045119", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045119", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:418021", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418021", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WAASCFW", "url": "https://omabrowser.org/oma/group/WAASCFW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YMK5", "url": "https://www.orthodb.org/?gene=A0A8V0YMK5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12911", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12911", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12911:SF22", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12911:SF22", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07738", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07738", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF18580", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18580", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015144116", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015144116", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YMK5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMK5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YMK5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMK5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSRRSQRLVTSRLYAEDEDGSSSLLGGPQLPFKESTARTAARRKSSGTKRPSPGPSTQTSYYSESLVSESYLGGSRGLAALDDALDGGTYWGRELSSRRRRDTGDTESSKVNGLLESRTYDTYASSSGYSSEDDYAGQLYSAHSSSGSGLRTAASRVGSFLWQVFTAPARFVGWLLSCIATAWHHVTGRSPQLQRVPLSRRYPRLKKSLWWLLLLLLLAAVTYGAWYLYPYGLSAHSFPVFSWWGVGRLSSSDMPGVRDMTALDQGLRGKQQLLARFQALEKRFEALEAAVSRWELGVAGGEPPPTGDVLGLLDGLLGRRQAGMEERLRSDVTGHLQGELDALRTQLQADMDKRLGKMAQASQEMEARLQELSREWQRSVQEELQGSWQRATGELQQEVSALRRELAGLRSDQEAMGKHLEAVLEQIKATRADVEAQMPAWISRFLAQPRQDTGTAGLLLQREDLQAELRALELRILAQMREERGLAARDSIGVALRQGGAGGVTEEQVHLIVDQALKRYSEDRVGMVDYALESAGASVINTRCSETYETKTALLSLFGIPLWYHSQSPRVILQPDVNPGNCWAFRGSQGFAVIRLSSLIRPTAVTLEHVPKALSPQGTIPSAPKDFTVYGLKEEREEEGLLLGRFTYNQDGDPIQTFYIKGDDVGAFQLVELRVLSNWGHPEYTCIYRFRVHGEPAL", "length": 698, "header": "tr|A0A8V0YMK5-1|A0A8V0YMK5_CHICK Isoform 1 of Sad1 and UNC84 domain containing 2 OS=Gallus gallus OX=9031 GN=SUN2 PE=1 SV=1 CANONICAL=A0A8V0YMK5-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YMK5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMK5/entry#A0A8V0YMK5-1", "sequence": { "sequence": "MSRRSQRLVTSRLYAEDEDGSSSLLGGPQLPFKESTARTAARRKSSGTKRPSPGPSTQTSYYSESLVSESYLGGSRGLAALDDALDGGTYWGRELSSRRRRDTGDTESSKVNGLLESRTYDTYASSSGYSSEDDYAGQLYSAHSSSGSGLRTAASRVGSFLWQVFTAPARFVGWLLSCIATAWHHVTGRSPQLQRVPLSRRYPRLKKSLWWLLLLLLLAAVTYGAWYLYPYGLSAHSFPVFSWWGVGRLSSSDMPGVRDMTALDQGLRGKQQLLARFQALEKRFEALEAAVSRWELGVAGGEPPPTGDVLGLLDGLLGRRQAGMEERLRSDVTGHLQGELDALRTQLQADMDKRLGKMAQASQEMEARLQELSREWQRSVQEELQGSWQRATGELQQEVSALRRELAGLRSDQEAMGKHLEAVLEQIKATRADVEAQMPAWISRFLAQPRQDTGTAGLLLQREDLQAELRALELRILAQMREERGLAARDSIGVALRQGGAGGVTEEQVHLIVDQALKRYSEDRVGMVDYALESAGASVINTRCSETYETKTALLSLFGIPLWYHSQSPRVILQPDVNPGNCWAFRGSQGFAVIRLSSLIRPTAVTLEHVPKALSPQGTIPSAPKDFTVYGLKEEREEEGLLLGRFTYNQDGDPIQTFYIKGDDVGAFQLVELRVLSNWGHPEYTCIYRFRVHGEPAL", "length": 698, "header": "tr|A0A8V0YMK5-1|A0A8V0YMK5_CHICK Isoform 1 of Sad1 and UNC84 domain containing 2 OS=Gallus gallus OX=9031 GN=SUN2 PE=1 SV=1 CANONICAL=A0A8V0YMK5-1" }, "locus": { "chromosome": "1", "start_pos": 50853774, "end_pos": 50848562, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010038410.1", "url": "https://www.ensembl.org/id/ENSGALT00010038410.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010022214.1", "url": "https://www.ensembl.org/id/ENSGALP00010022214.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:418021", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418021", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "G3I2J5-1", "protein_name": "SUN domain-containing protein 2 isoform X2", "gene_name": "Sun2", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSRRSQRLTRYSQDDNDGSSSSGASSVAGSQSTLFKDSPLRTLKRKSSNMKRLSPAPQLGPSSDSHTSYYSESVVRESYIGSPRAASLARSALLDDRLHSEPYWSGDLRGRRRRGTGGSESSKANGLTTESKVSEDFFGSSSGYSSEDDFAGYMESDQHGSGSGLRSAASRAGSFVWTLVTFPGRLFGLLYWWVGTTWYRLTTAASLLDVFVLTRSRHFSLNLKTFLWFLLFLLLLTVLTYGAWYFYPFGLHTLQPTLASWWAAKESKRQPEVWESRDASPHFQAEQRILSRVYSLERRLEALAAEFSSNWQKEAIRLERLELRQGATGHGGGSGLSHEDTLTLLEGLVSRREAALKEDLRRDTMSRIQEELATLRAEHHQDSEDLFRKIVQASQESEAHVQQLKTEWQRMTQEAFQESSVKELGQLEAQLASLRQELAALTLRQNSVADEVGLLPQKIQAARADVESQFPDWVSRFLLRDKGASSGLLQRDELHAQLQELESKILASMAEMQGKSAREAAASLGQTLQKEGVVGVTEEQVHQIVKQALQRYSEDRIGMVDYALESGGASVISTRCSETYETKTALLSLFGIPLWYHSQSPRVILQPDVHPGNCWAFQGPQGFAVVRLSARIRPTAVTLEHVPKALSPNSTISSAPKDFAIFGFDEDLQQEGTLLGTFAYDQDGEPIQTFYFQTSKMATYQVVELRILTNWGHPEYTCIYRFRVHGEPAH", "length": 730 }, "evidence": [ { "id": "A0A8V0YMK5", "url": "https://omabrowser.org/oma/group/A0A8V0YMK5/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q8BJS4-1", "protein_name": "SUN domain-containing protein 2", "gene_name": "Sun2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSRRSQRLTRYSQDDNDGGSSSSGASSVAGSQGTVFKDSPLRTLKRKSSNMKHLSPAPQLGPSSDSHTSYYSESVVRESYIGSPRAVSLARSALLDDHLHSEPYWSGDLRGRRRRGTGGSESSKANGLTAESKASEDFFGSSSGYSSEDDLAGYTDSDQHSSGSRLRSAASRAGSFVWTLVTFPGRLFGLLYWWIGTTWYRLTTAASLLDVFVLTRSRHFSLNLKSFLWFLLLLLLLTGLTYGAWHFYPLGLQTLQPAVVSWWAAKESRKQPEVWESRDASQHFQAEQRVLSRVHSLERRLEALAADFSSNWQKEAIRLERLELRQGAAGHGGGSSLSHEDALSLLEGLVSRREATLKEDLRRDTVAHIQEELATLRAEHHQDSEDLFKKIVQASQESEARVQQLKTEWKSMTQEAFQESSVKELGRLEAQLASLRQELAALTLKQNSVADEVGLLPQKIQAARADVESQFPDWIRQFLLGDRGARSGLLQRDEMHAQLQELENKILTKMAEMQGKSAREAAASLGQILQKEGIVGVTEEQVHRIVKQALQRYSEDRIGMVDYALESGGASVISTRCSETYETKTALLSLFGIPLWYHSQSPRVILQPDVHPGNCWAFQGPQGFAVVRLSARIRPTAVTLEHVPKALSPNSTISSAPKDFAIFGFDEDLQQEGTLLGTFAYDQDGEPIQTFYFQASKMATYQVVELRILTNWGHPEYTCIYRFRVHGEPAH", "length": 731 }, "evidence": [ { "id": "A0A8V0YMK5", "url": "https://omabrowser.org/oma/group/A0A8V0YMK5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9UH99-1", "protein_name": "SUN domain-containing protein 2", "gene_name": "SUN2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSRRSQRLTRYSQGDDDGSSSSGGSSVAGSQSTLFKDSPLRTLKRKSSNMKRLSPAPQLGPSSDAHTSYYSESLVHESWFPPRSSLEELHGDANWGEDLRVRRRRGTGGSESSRASGLVGRKATEDFLGSSSGYSSEDDYVGYSDVDQQSSSSRLRSAVSRAGSLLWMVATSPGRLFRLLYWWAGTTWYRLTTAASLLDVFVLTRRFSSLKTFLWFLLPLLLLTCLTYGAWYFYPYGLQTFHPALVSWWAAKDSRRPDEGWEARDSSPHFQAEQRVMSRVHSLERRLEALAAEFSSNWQKEAMRLERLELRQGAPGQGGGGGLSHEDTLALLEGLVSRREAALKEDFRRETAARIQEELSALRAEHQQDSEDLFKKIVRASQESEARIQQLKSEWQSMTQESFQESSVKELRRLEDQLAGLQQELAALALKQSSVAEEVGLLPQQIQAVRDDVESQFPAWISQFLARGGGGRVGLLQREEMQAQLRELESKILTHVAEMQGKSAREAAASLSLTLQKEGVIGVTEEQVHHIVKQALQRYSEDRIGLADYALESGGASVISTRCSETYETKTALLSLFGIPLWYHSQSPRVILQPDVHPGNCWAFQGPQGFAVVRLSARIRPTAVTLEHVPKALSPNSTISSAPKDFAIFGFDEDLQQEGTLLGKFTYDQDGEPIQTFHFQAPTMATYQVVELRILTNWGHPEYTCIYRFRVHGEPAH", "length": 717 }, "evidence": [ { "id": "A0A8V0YMK5", "url": "https://omabrowser.org/oma/group/A0A8V0YMK5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "nucleokinesis involved in cell motility in cerebral cortex radial glia guided migration", "id": "GO:0021817", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021817", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMK5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMK5" } ], "pmid": "" }, { "name": "nuclear migration along microfilament", "id": "GO:0031022", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031022", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMK5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMK5" } ], "pmid": "" }, { "name": "nuclear matrix anchoring at nuclear membrane", "id": "GO:0090292", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090292", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMK5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMK5" } ], "pmid": "" }, { "name": "positive regulation of cell migration", "id": "GO:0030335", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030335", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMK5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMK5" } ], "pmid": "" }, { "name": "centrosome localization", "id": "GO:0051642", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051642", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMK5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMK5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "condensed nuclear chromosome", "id": "GO:0000794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000794", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMK5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMK5" } ], "pmid": "" }, { "name": "nuclear envelope", "id": "GO:0005635", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005635", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMK5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMK5" } ], "pmid": "" }, { "name": "nuclear inner membrane", "id": "GO:0005637", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005637", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMK5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMK5" } ], "pmid": "" }, { "name": "chromosome, telomeric region", "id": "GO:0000781", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000781", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMK5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMK5" } ], "pmid": "" }, { "name": "meiotic nuclear membrane microtubule tethering complex", "id": "GO:0034993", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034993", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMK5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMK5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMK5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMK5" } ], "pmid": "" }, { "name": "protein-membrane adaptor activity", "id": "GO:0043495", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043495", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMK5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMK5" } ], "pmid": "" }, { "name": "lamin binding", "id": "GO:0005521", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005521", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMK5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMK5" } ], "pmid": "" }, { "name": "cytoskeleton-nuclear membrane anchor activity", "id": "GO:0140444", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140444", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMK5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMK5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YMK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMK5" }, { "id": "PS51469", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51469" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SUN", "eco_id": "ECO_0000259", "start_pos": 536, "end_pos": 697, "start_aa": "Gly", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YMM6-1", "uniprot_ac": "A0A8V0YMM6", "uniprot_id": "A0A8V0YMM6_CHICK", "mass": { "chemical_mass": 129607.0, "monoisotopic_mass": 129607.0 }, "refseq": {}, "gene_names": [ { "name": "CHRD", "type": "recommended", "evidence": [ { "id": "A0A8V0YMM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMM6" } ] } ], "protein_names": [ { "name": "Chordin", "type": "recommended", "evidence": [ { "id": "A0A8V0YMM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMM6/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMM6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMM6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CHRD", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMM6", "locus": { "chromosome": "9", "start_pos": 15631546, "end_pos": 15640316, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010015908", "url": "https://www.ensembl.org/id/ENSGALG00010015908" } ] } } ], "crossref": [ { "id": "A0A8V0YMM6", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YMM6", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR001007", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001007", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR010895", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010895", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016353", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016353", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052278", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052278", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YMM2", "url": "https://www.orthodb.org/?gene=A0A8V0YMM2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YMM6", "url": "https://www.orthodb.org/?gene=A0A8V0YMM6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YUA2", "url": "https://www.orthodb.org/?gene=A0A8V0YUA2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YUD4", "url": "https://www.orthodb.org/?gene=A0A8V0YUD4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z0R4", "url": "https://www.orthodb.org/?gene=A0A8V0Z0R4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46526", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46526", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46526:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46526:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00093", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00093", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07452", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07452", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YMM2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMM2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YMM2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMM2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YMM6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMM6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YMM6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMM6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YUA2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUA2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YUA2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUA2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YUD4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUD4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YUD4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUD4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z0R4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z0R4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z0R4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z0R4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPQFPPCQGRGSPSFPSFPGKGRELPLLLPHIPAAEPGDCDELRVRGASGGFLAPAGRPTAIARLLLPALPRSLPAVPPGLRHGGGHRAVTLARPRSPQPSPATGSQANRDNGREEQGQAFPWCLLPAHHRCCPHQPGHMWVKSRIRAGCCSRTLGRGTSLGPQVLSPRSWERSCGPALGLPSAPGFGDAKGTCCGGSQLPLAHAAAYKAGPGPAAGQRRWQRRQQAAPGPPSPPPAARFPRFPGTMRTALLLLALLALPVRTARPKLALPIRPDSEPLPPGGAAGCAFGGRFYALEETWHPDLGEPFGVMRCVICHCETQRNRRGKPVGKVNCKNMKQDCPVPTCPRATLLPGHCCHTCPKALPGAPEKSYKPPFDTFEYFQDKEDELDKPYNDRSYLSSEGSARDDARTEFVALLTSGPEPWHPTSSAVAKARFTLLRSYLLFSISYERLGRPSRVRFSDPEGTVLFEHPVQKSAAPEDGMLCGMWRTVSKANIQLLRAEQLRVSLVTRAQPSGEVHGHILKHRALFAETFGAILTSSDPVHLGAGGMAMLTLSDTENNLHFILMARGLLEPGAEESPWVPLRVRILHQGQTLREAHANITMEDPDFAEVLSDLSAHELQWLAQGQLRIVADTQGRHPRQLEGTITARRSCDTIQSVLCGADALQPTKTGAVGSAKLALHENGTLEYQVRVVGTGSEVVGVTLETKPRRKNRRNVLFDMTPSYRAGMAQGVWHSPSARDVHMLLQNELFLNVATKDWAEGELRGQVISLPYSGLLARYTEMPVPLAGQLVSPPVSSGAGGHAWLSLDEHCHLHYEIVVAGLGRPADGTVSAQLHGVAELGEMGTRPHLHKRMLKGFYGTEAQGVVKDLDAELLQHLAQGTAFLQVSTKAHPRGEMRGWVHIPNRCQPGGARLSTGEAELSEGPKGRNVEQLKKDPNSCFFEGQHHAHGTRWAPDYDKKCSICSCQKRTVICDPILCQPLNCTRQVHPEELCCPICEEKKMEQEELKLERARDSSEGCYFDGDKTWRGSGTRWHPVVPPFGLIKCAICTCKGTTGEVHCEKVQCPRLTCANPVRVSPSDCCKQCPAPEKSIPELTDGMQADGPRACRFGRRWYLNNESWHPSVPPFGEMKCILCWCVSGETHCQRQECPPDACASPTRRDNPCCAKCRAPDAPSEKMHEATAEAWSR", "length": 1188, "header": "tr|A0A8V0YMM6-1|A0A8V0YMM6_CHICK Isoform 1 of Chordin OS=Gallus gallus OX=9031 GN=CHRD PE=4 SV=1 CANONICAL=A0A8V0YMM6-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YMM2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMM6/entry#A0A8V0YMM2-1", "sequence": { "sequence": "MVSAPCPPPLLPSSARAHVGEEQDPCWVLFPYPRPRHLPGTPGLVPTLVGTVLWSCSGIAICTRIWGCQRHMLWGCAFGGRFYALEETWHPDLGEPFGVMRCVICHCETQRNRRGKPVGKVNCKNMKQDCPVPTCPRATLLPGHCCHTCPKALPGAPEKSYKPPFDTFEYFQDKEDELDKPYNDRSYLSSEGSARDDARTEFVALLTSGPEPWHPTSSAVAKARFTLLRSYLLFSISYERLGRPSRVRFSDPEGTVLFEHPVQKSAAPEDGMLCGMWRTVSKANIQLLRAEQLRVSLVTRAQPSGEVHGHILKHRALFAETFGAILTSSDPVHLGAGGMAMLTLSDTENNLHFILMARGLLEPGAEESPWVPLRVRILHQGQTLREAHANITMEDPDFAEVLSDLSAHELQWLAQGQLRIVADTQGRHPRQLEGTITARRSCDTIQSVLCGADALQPTKTGAVGSAKLALHENGTLEYQVRVVGTGSEVVGVTLETKPRRKNRRNVLFDMTPSYRAGMAQGVWHSPSARDVHMLLQNELFLNVATKDWAEGELRGQVISLPYSGLLARYTEMPVPLAGQLVSPPVSSGAGGHAWLSLDEHCHLHYEIVVAGLGRPADGTVSAQLHGVAELGEMGTRPHLHKRMLKGFYGTEAQGVVKDLDAELLQHLAQGTAFLQVSTKAHPRGEMRGWVHIPNRCQPGGARLSTGEAELSEGPKGRNVEQLKKDPNSCFFEGQHHAHGTRWAPDYDKKCSICSCQKRTVICDPILCQPLNCTRQVHPEELCCPICEEKKMEQEELKLERARDSSEGCYFDGDKTWRGSGTRWHPVVPPFGLIKCAICTCKGTTGEVHCEKVQCPRLTCANPVRVSPSDCCKQCPAPEKSIPELTDGMQADGPRACRFGRRWYLNNESWHPSVPPFGEMKCILCWCVSGETHCQRQECPPDACASPTRRDNPCCAKCRAPDAPSEKMHEATAEAWSR", "length": 977, "header": "tr|A0A8V0YMM2-1|A0A8V0YMM2_CHICK Computationally mapped isoform of Chordin OS=Gallus gallus OX=9031 GN=CHRD PE=3 SV=1 CANONICAL=A0A8V0YMM6-1" }, "locus": { "chromosome": "9", "start_pos": 15639188, "end_pos": 15631912, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010038437.1", "url": "https://www.ensembl.org/id/ENSGALT00010038437.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010022229.1", "url": "https://www.ensembl.org/id/ENSGALP00010022229.1" } ] } }, { "isoform_ac": "A0A8V0YMM6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMM6/entry#A0A8V0YMM6-1", "sequence": { "sequence": 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"length": 1188, "header": "tr|A0A8V0YMM6-1|A0A8V0YMM6_CHICK Isoform 1 of Chordin OS=Gallus gallus OX=9031 GN=CHRD PE=4 SV=1 CANONICAL=A0A8V0YMM6-1" }, "locus": { "chromosome": "9", "start_pos": 15640117, "end_pos": 15631912, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010038443.1", "url": "https://www.ensembl.org/id/ENSGALT00010038443.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010022234.1", "url": "https://www.ensembl.org/id/ENSGALP00010022234.1" } ] } }, { "isoform_ac": "A0A8V0YUA2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMM6/entry#A0A8V0YUA2-1", "sequence": { "sequence": "MLHSPPSPPRRRPPLQHPPERNRRGKPVGKVNCKNMKQDCPVPTCPRATLLPGHCCHTCPKALPGAPEKSYKPPFDTFEYFQDKEDELDKPYNDRSYLSSEGSARDDARTEFVALLTSGPEPWHPTSSAVAKARFTLLRSYLLFSISYERLGRPSRVRFSDPEGTVLFEHPVQKSAAPEDGMLCGMWRTVSKANIQLLRAEQLRVSLVTRAQPSGEVHGHILKHRALFAETFGAILTSSDPVHLGAGGMAMLTLSDTENNLHFILMARGLLEPGAEESPWVPLRVRILHQGQTLREAHANITMEDPDFAEVLSDLSAHELQWLAQGQLRIVADTQGRHPRQLEGTITARRSCDTIQSVLCGADALQPTKTGAVGSAKLALHENGTLEYQVRVVGTGSEVVGVTLETKPRRKNRRNVLFDMTPSYRAGMAQGVWHSPSARDVHMLLQNELFLNVATKDWAEGELRGQVISLPYSGLLARYTEMPVPLAGQLVSPPVSSGAGGHAWLSLDEHCHLHYEIVVAGLGRPADGTVSAQLHGVAELGEMGTRPHLHKRMLKGFYGTEAQGVVKDLDAELLQHLAQGTAFLQVSTKAHPRGEMRGWVHIPNRCQPGGARLSTGEAELSEGPKGRNVEQLKKDPNSCFFEGQHHAHGTRWAPDYDKKCSICSCQKRTVICDPILCQPLNCTRQVHPEELCCPICEEKKMEQEELKLERARDSSEGCYFDGDKTWRGSGTRWHPVVPPFGLIKCAICTCKGTTGEVHCEKVQCPRLTCANPVRVSPSDCCKQCPAPEKSIPELTDGMQADGPRACRFGRRWYLNNESWHPSVPPFGEMKCILCWCVSGETHCQRQECPPDACASPTRRDNPCCAKCRAPDAPSEKMHEATAEAWSR", "length": 887, "header": "tr|A0A8V0YUA2-1|A0A8V0YUA2_CHICK Computationally mapped isoform of Chordin OS=Gallus gallus OX=9031 GN=CHRD PE=3 SV=1 CANONICAL=A0A8V0YMM6-1" }, "locus": { "chromosome": "9", "start_pos": 15637415, "end_pos": 15631912, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010038382.1", "url": "https://www.ensembl.org/id/ENSGALT00010038382.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010022193.1", "url": "https://www.ensembl.org/id/ENSGALP00010022193.1" } ] } }, { "isoform_ac": "A0A8V0YUD4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMM6/entry#A0A8V0YUD4-1", "sequence": { "sequence": "MWVKSRIRAGCCSRTLGRGTSLGPQVLSPRSWERSCGPALGLPSAPGFGDAKGTCCGQRNRRGKPVGKVNCKNMKQDCPVPTCPRATLLPGHCCHTCPKALPGAPEKSYKPPFDTFEYFQDKEDELDKPYNDRSYLSSEGSARDDARTEFVALLTSGPEPWHPTSSAVAKARFTLLRSYLLFSISYERLGRPSRVRFSDPEGTVLFEHPVQKSAAPEDGMLCGMWRTVSKANIQLLRAEQLRVSLVTRAQPSGEVHGHILKHRALFAETFGAILTSSDPVHLGAGGMAMLTLSDTENNLHFILMARGLLEPGAEESPWVPLRVRILHQGQTLREAHANITMEDPDFAEVLSDLSAHELQWLAQGQLRIVADTQGRHPRQLEGTITARRSCDTIQSVLCGADALQPTKTGAVGSAKLALHENGTLEYQVRVVGTGSEVVGVTLETKPRRKNRRNVLFDMTPSYRAGMAQGVWHSPSARDVHMLLQNELFLNVATKDWAEGELRGQVISLPYSGLLARYTEMPVPLAGQLVSPPVSSGAGGHAWLSLDEHCHLHYEIVVAGLGRPADGTVSAQLHGVAELGEMGTRPHLHKRMLKGFYGTEAQGVVKDLDAELLQHLAQGTAFLQVSTKAHPRGEMRGWVHIPNRCQPGGARLSTGEAELSEGPKGRNVEQLKKDPNSCFFEGQHHAHGTRWAPDYDKKCSICSCQKRTVICDPILCQPLNCTRQVHPEELCCPICEEKKMEQEELKLERARDSSEGCYFDGDKTWRGSGTRWHPVVPPFGLIKCAICTCKGTTGEVHCEKVQCPRLTCANPVRVSPSDCCKQCPAPEKSIPELTDGMQADGPRACRFGRRWYLNNESWHPSVPPFGEMKCILCWCVSGETHCQRQECPPDACASPTRRDNPCCAKCRAPDAPSEKMHEATAEAWSR", "length": 925, "header": "tr|A0A8V0YUD4-1|A0A8V0YUD4_CHICK Computationally mapped isoform of Chordin OS=Gallus gallus OX=9031 GN=CHRD PE=3 SV=1 CANONICAL=A0A8V0YMM6-1" }, "locus": { "chromosome": "9", "start_pos": 15639136, "end_pos": 15631912, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010038427.1", "url": "https://www.ensembl.org/id/ENSGALT00010038427.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010022223.1", "url": "https://www.ensembl.org/id/ENSGALP00010022223.1" } ] } }, { "isoform_ac": "A0A8V0Z0R4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMM6/entry#A0A8V0Z0R4-1", "sequence": { "sequence": "MRTALLLLALLALPVRTARPKLALPIRPDSEPLPPGGAAGCAFGGRFYALEETWHPDLGEPFGVMRCVICHCETQRNRRGKPVGKVNCKNMKQDCPVPTCPRATLLPGHCCHTCPKALPGAPEKSYKPPFDTFEYFQDKEDELDKPYNDRSYLSSEGSARDDARTEFVALLTSGPEPWHPTSSAVAKARFTLLRSYLLFSISYERLGRPSRVRFSDPEGTVLFEHPVQKSAAPEDGMLCGMWRTVSKANIQLLRAEQLRVSLVTRAQPSGEVHGHILKHRALFAETFGAILTSSDPVHLGAGGMAMLTLSDTENNLHFILMARGLLEPGAEESPWVPLRVRILHQGQTLREAHANITMEVQPSPSPAQRAIQSVLCGADALQPTKTGAVGSAKLALHENGTLEYQVRVVGTGSEVVGVTLETKPRRKNRRNVLFDMTPSYRAQGVWHSPSARDVHMLLQNELFLNVATKDWAEGELRGQVISLPYSGLLARYTEMPVPLAGQLVSPPVSSGAGGHAWLSLDEHCHLHYEIVVAGLGRPADGTVSAQLHGVAELGEMGTRPHLHKRMLKGFYGTEAQGVVKDLDAELLQHLAQGTAFLQVSTKAHPRGEMRGWVHIPNRCQPGGARLSTGEAELSEGPKGRNVEQLKKDPNSCFFEGQHHAHGTRWAPDYDKKCSICSCQKRTVICDPILCQPLNCTRQVHPEELCCPICEEKKMEQEELKLERARDSSEGEFPGHRHGEPCACSPQGTTGEVHCEKVQCPRLTCANPVRVSPSDCCKQCPAPEKSIPELTDGMQADGPRACRFGRRWYLNNESWHPSVPPFGEMKCILCWCVSGETHCQRQECPPDACASPTRRDNPCCAKCRAPDAPSEKMHEATAEAWSR", "length": 882, "header": "tr|A0A8V0Z0R4-1|A0A8V0Z0R4_CHICK Computationally mapped isoform of Chordin OS=Gallus gallus OX=9031 GN=CHRD PE=3 SV=1 CANONICAL=A0A8V0YMM6-1" }, "locus": { "chromosome": "9", "start_pos": 15638151, "end_pos": 15631912, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010038423.1", "url": "https://www.ensembl.org/id/ENSGALT00010038423.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010022220.1", "url": "https://www.ensembl.org/id/ENSGALP00010022220.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 10, "go_terms": [ { "name": "spinal cord dorsal/ventral patterning", "id": "GO:0021513", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021513", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMM6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMM6" } ], "pmid": "" }, { "name": "positive regulation of cell adhesion", "id": "GO:0045785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045785", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMM6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMM6" } ], "pmid": "" }, { "name": "negative regulation of cell migration", "id": "GO:0030336", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030336", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMM6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMM6" } ], "pmid": "" }, { "name": "BMP signaling pathway", "id": "GO:0030509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030509", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMM6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMM6" } ], "pmid": "" }, { "name": "negative regulation of BMP signaling pathway", "id": "GO:0030514", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030514", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMM6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMM6" } ], "pmid": "" }, { "name": "dorsal/ventral pattern formation", "id": "GO:0009953", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009953", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMM6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMM6" } ], "pmid": "" }, { "name": "negative regulation of osteoblast differentiation", "id": "GO:0045668", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045668", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMM6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMM6" } ], "pmid": "" }, { "name": "positive regulation of mesenchymal cell proliferation", "id": "GO:0002053", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002053", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMM6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMM6" } ], "pmid": "" }, { "name": "system development", "id": "GO:0048731", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048731", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMM6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMM6" } ], "pmid": "" }, { "name": "pattern specification process", "id": "GO:0007389", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007389", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMM6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMM6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMM6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMM6" } ], "pmid": "" }, { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMM6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMM6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "BMP binding", "id": "GO:0036122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036122", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMM6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMM6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1117, "end_pos": 1119, "annotation": "n_glycosylation_sequon" }, { "start_pos": 601, "end_pos": 603, "annotation": "n_glycosylation_sequon" }, { "start_pos": 684, "end_pos": 686, "annotation": "n_glycosylation_sequon" }, { "start_pos": 982, "end_pos": 984, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YMM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMM6" }, { "id": "PS50933", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50933" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CHRD", "eco_id": "ECO_0000259", "start_pos": 409, "end_pos": 527, "start_aa": "Ala", "end_aa": "Ala", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0YMM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMM6" }, { "id": "PS50184", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50184" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "VWFC", "eco_id": "ECO_0000259", "start_pos": 285, "end_pos": 361, "start_aa": "Ala", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1117, "end_pos": 1119 }, { "start_pos": 601, "end_pos": 603 }, { "start_pos": 684, "end_pos": 686 }, { "start_pos": 982, "end_pos": 984 } ] }, "class_list": [], "section_stats": [ { 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"count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YMN1-1", "uniprot_ac": "A0A8V0YMN1", "uniprot_id": "A0A8V0YMN1_CHICK", "mass": { "chemical_mass": 126732.0, "monoisotopic_mass": 126732.0 }, "refseq": {}, "gene_names": [ { "name": "CTSA", "type": "recommended", "evidence": [ { "id": "A0A8V0YMN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMN1" } ] } ], "protein_names": [ { "name": "Lysosomal protective protein", "type": "recommended", "evidence": [ { "id": "A0A8V0YMN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMN1/entry#names_and_taxonomy" } ] }, { "name": "3.4.16.5", "type": "synonym", "evidence": [ { "id": "A0A8V0YMN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMN1/entry#names_and_taxonomy" } ] }, { "name": "Cathepsin A", "type": "synonym", "evidence": [ { "id": "A0A8V0YMN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMN1/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Protective protein appears to be essential for both the activity of beta-galactosidase and neuraminidase, it associates with these enzymes and exerts a protective function necessary for their stability and activity. This protein is also a carboxypeptidase and can deamidate tachykinins.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z0S9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z0S9#function" }, { "database": "UniProtKB", "id": "ARBA00054649", "url": "https://www.uniprot.org/uniprotkb/ARBA00054649#function" }, { "database": "UniProtKB", "id": "A0A8V0YMN1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMN1#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMN1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMN1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CTSA", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMN1", "locus": { "chromosome": "20", "start_pos": 10874955, "end_pos": 10861288, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010015954", "url": "https://www.ensembl.org/id/ENSGALG00010015954" } ] } } ], "crossref": [ { "id": "A0A8V0YMN1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YMN1", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR001563", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001563", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006564", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006564", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007527", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007527", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018202", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018202", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029058", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029058", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033124", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033124", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045563", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045563", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048324", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048324", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048325", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048325", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048326", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048326", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052579", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052579", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR11802", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11802", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11802:SF502", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11802:SF502", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31569", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31569", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31569:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31569:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00450", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00450", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF04434", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04434", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF19286", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19286", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21056", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21056", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21599", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21599", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21600", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21600", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YMN1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMN1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YMN1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMN1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z0S9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z0S9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z0S9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z0S9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MELGACFRTYREFKESLCAYQQAYGSHYSLRSCTSVRFHNREHGTAVREDVMFMQVKFGCTRTQKYSKKRKKQPNLCPAYFVLEYNEDIDQLMISELCSDHVHVDTEFFLTEGITRGASTTADGSPAVKLRRQQADGTESSNEVGENLPEADQFVDGASALCRVPALSEAGKENDSSSAAARVTEVVKNCLNADSGALASVDVGSDQGLERLNFQTSKMKSLFMKFPASLLLHRARSERGHVLYVLLVESKERVGKIVHWSALKADTGESISKMLTVFKEFNPEWQKVKVVFVDVSFLHKAVLQELFPLAQVLLSVYHTVRLLEENVNAAGMPECAKHEMKLALKKAVFSTSADSLDTLSQMMKSVVNTELYNYLQANWFSCELLWYMHTKKGLHSCSAHIDSLDLITHRLSALFGQHSSLEASVLHLLECAECLDSKLLEGSNWSPSCTKDCQRGFQEKPEAQVCAATKPDPPVVSQVPTERPEPPRHVVPSVVVEGQGCMLEALRDSCTALDYQLCSSEWEVVQMSTQLISAVPGGVEVRLLEDAHRVRADRWSCSCYFHHRYRLPCRHVLAVLHADRRSVESGMVGHRWQRKYQQSAAPAEMPQHGGTPVEEEGRRDRIQALSKELANLLLQSDGTQLEERSSALRAIVDAWAEMLPLLCALLLALGPAHAAPAGHEVTYLPGLPKQPSFRHFSGHLCIGPTQRLHYWFVEAQNNPQGSPLVLWLNGGPGCSSMEGFLKEHGPFLVQPDGVTLKYNDYAWNKIANMLYLESPAGVGFSYSEDKKYATNDTEVAHNNYLALKEFLRLFPEYSKNDLFLTGESYGGVYIPTLAEWVMQDPSLNLKGIAVGNGLSSYEINDNSLVYFAYYHGLLGTQLWKDLQTFCCSEGKCNFHDNSNLNCTLKMAEMIEIVEESGLNIYNLYAPCAGGVPGSMRYEGDYLVTHDLGNSFIRMPMRFSWRQNLFRMPVARNKVRMDPPCTNSTAPTMYLNSPEVRKALHISPDAPEWQVCSFEVNRSYKRLYMQMNDQYLKLLGAMKYRILVYNGDVDMACNFLGDEWFVDSLCQKVQVARRPWLYTVGGENQIGGFVKEFTNIAFLTVKGAGHMVPTDQPLAAFTMFSRFIKNEPY", "length": 1128, "header": "tr|A0A8V0YMN1-1|A0A8V0YMN1_CHICK Isoform 1 of Lysosomal protective protein OS=Gallus gallus OX=9031 GN=CTSA PE=1 SV=1 CANONICAL=A0A8V0YMN1-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YMN1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMN1/entry#A0A8V0YMN1-1", "sequence": { "sequence": "MELGACFRTYREFKESLCAYQQAYGSHYSLRSCTSVRFHNREHGTAVREDVMFMQVKFGCTRTQKYSKKRKKQPNLCPAYFVLEYNEDIDQLMISELCSDHVHVDTEFFLTEGITRGASTTADGSPAVKLRRQQADGTESSNEVGENLPEADQFVDGASALCRVPALSEAGKENDSSSAAARVTEVVKNCLNADSGALASVDVGSDQGLERLNFQTSKMKSLFMKFPASLLLHRARSERGHVLYVLLVESKERVGKIVHWSALKADTGESISKMLTVFKEFNPEWQKVKVVFVDVSFLHKAVLQELFPLAQVLLSVYHTVRLLEENVNAAGMPECAKHEMKLALKKAVFSTSADSLDTLSQMMKSVVNTELYNYLQANWFSCELLWYMHTKKGLHSCSAHIDSLDLITHRLSALFGQHSSLEASVLHLLECAECLDSKLLEGSNWSPSCTKDCQRGFQEKPEAQVCAATKPDPPVVSQVPTERPEPPRHVVPSVVVEGQGCMLEALRDSCTALDYQLCSSEWEVVQMSTQLISAVPGGVEVRLLEDAHRVRADRWSCSCYFHHRYRLPCRHVLAVLHADRRSVESGMVGHRWQRKYQQSAAPAEMPQHGGTPVEEEGRRDRIQALSKELANLLLQSDGTQLEERSSALRAIVDAWAEMLPLLCALLLALGPAHAAPAGHEVTYLPGLPKQPSFRHFSGHLCIGPTQRLHYWFVEAQNNPQGSPLVLWLNGGPGCSSMEGFLKEHGPFLVQPDGVTLKYNDYAWNKIANMLYLESPAGVGFSYSEDKKYATNDTEVAHNNYLALKEFLRLFPEYSKNDLFLTGESYGGVYIPTLAEWVMQDPSLNLKGIAVGNGLSSYEINDNSLVYFAYYHGLLGTQLWKDLQTFCCSEGKCNFHDNSNLNCTLKMAEMIEIVEESGLNIYNLYAPCAGGVPGSMRYEGDYLVTHDLGNSFIRMPMRFSWRQNLFRMPVARNKVRMDPPCTNSTAPTMYLNSPEVRKALHISPDAPEWQVCSFEVNRSYKRLYMQMNDQYLKLLGAMKYRILVYNGDVDMACNFLGDEWFVDSLCQKVQVARRPWLYTVGGENQIGGFVKEFTNIAFLTVKGAGHMVPTDQPLAAFTMFSRFIKNEPY", "length": 1128, "header": "tr|A0A8V0YMN1-1|A0A8V0YMN1_CHICK Isoform 1 of Lysosomal protective protein OS=Gallus gallus OX=9031 GN=CTSA PE=1 SV=1 CANONICAL=A0A8V0YMN1-1" }, "locus": { "chromosome": "20", "start_pos": 10874381, "end_pos": 10861300, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010038450.1", "url": "https://www.ensembl.org/id/ENSGALT00010038450.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010022239.1", "url": "https://www.ensembl.org/id/ENSGALP00010022239.1" } ] } }, { "isoform_ac": "A0A8V0Z0S9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMN1/entry#A0A8V0Z0S9-1", "sequence": { "sequence": "MGAGHVPRGAATAGSGCGVSGMLPLLCALLLALGPAHAAPAGHEVTYLPGLPKQPSFRHFSGHLCIGPTQRLHYWFVEAQNNPQGSPLVLWLNGGPGCSSMEGFLKEHGPFLVQPDGVTLKYNDYAWNKIANMLYLESPAGVGFSYSEDKKYATNDTEVAHNNYLALKEFLRLFPEYSKNDLFLTGESYGGVYIPTLAEWVMQDPSLNLKGIAVGNGLSSYEINDNSLVYFAYYHGLLGTQLWKDLQTFCCSEGKCNFHDNSNLNCTLKMAEMIEIVEESGLNIYNLYAPCAGGVPGSMRYEGDYLVTHDLGNSFIRMPMRFSWRQNLFRMPVARNKVRMDPPCTNSTAPTMYLNSPEVRKALHISPDAPEWQVCSFEVNRSYKRLYMQMNDQYLKLLGAMKYRILVYNGDVDMACNFLGDEWFVDSLCQKVQVARRPWLYTVGGENQIGGFVKEFTNIAFLTVKGAGHMVPTDQPLAAFTMFSRFIKNEPY", "length": 492, "header": "tr|A0A8V0Z0S9-1|A0A8V0Z0S9_CHICK Computationally mapped isoform of Carboxypeptidase OS=Gallus gallus OX=9031 GN=CTSA PE=1 SV=1 CANONICAL=A0A8V0YMN1-1" }, "locus": { "chromosome": "20", "start_pos": 10874381, "end_pos": 10871007, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010038445.1", "url": "https://www.ensembl.org/id/ENSGALT00010038445.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010022235.1", "url": "https://www.ensembl.org/id/ENSGALP00010022235.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 705, "start_aa": "Thr", "end_pos": 705, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr705", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "negative regulation of chaperone-mediated autophagy", "id": "GO:1904715", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904715", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMN1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMN1" } ], "pmid": "" }, { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMN1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMN1" } ], "pmid": "" }, { "name": "regulation of protein stability", "id": "GO:0031647", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031647", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMN1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMN1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMN1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMN1" } ], "pmid": "" }, { "name": "serine-type carboxypeptidase activity", "id": "GO:0004185", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004185", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMN1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMN1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1016, "end_pos": 1018, "annotation": "n_glycosylation_sequon" }, { "start_pos": 174, "end_pos": 176, "annotation": "n_glycosylation_sequon" }, { "start_pos": 444, "end_pos": 446, "annotation": "n_glycosylation_sequon" }, { "start_pos": 791, "end_pos": 793, "annotation": "n_glycosylation_sequon" }, { "start_pos": 901, "end_pos": 903, "annotation": "n_glycosylation_sequon" }, { "start_pos": 982, "end_pos": 984, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YMN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMN1" }, { "id": "PS50966", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50966" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SWIM-type", "eco_id": "ECO_0000259", "start_pos": 539, "end_pos": 580, "start_aa": "Val", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "3.4.16.5", "ec_name": "Release of a C-terminal amino acid with broad specificity.", "evidence": [ { "id": "3.4.16.5", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=3.4.16.5" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 705 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1016, "end_pos": 1018 }, { "start_pos": 174, "end_pos": 176 }, { "start_pos": 444, "end_pos": 446 }, { "start_pos": 791, "end_pos": 793 }, { "start_pos": 901, "end_pos": 903 }, { "start_pos": 982, "end_pos": 984 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", 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"field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YMN6-1", "uniprot_ac": "A0A8V0YMN6", "uniprot_id": "A0A8V0YMN6_CHICK", "mass": { "chemical_mass": 110850.0, "monoisotopic_mass": 110850.0 }, "refseq": { "ac": "XP_001234609", "name": "cytokine receptor common subunit beta isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001234609" }, "gene_names": [ { "name": "CRCBL", "type": "recommended", "evidence": [ { "id": "A0A8V0YMN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMN6" } ] }, { "name": "CRCBL", "type": "synonym", "evidence": [ { "id": "XP_001234609", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001234609" } ] } ], "protein_names": [ { "name": "Fibronectin type-III domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A8V0YMN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMN6/entry#names_and_taxonomy" } ] }, { "name": "cytokine receptor common subunit beta isoform X1", "type": "synonym", "evidence": [ { "id": "XP_001234609", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001234609" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 1% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_001234609.5. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_001234609", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001234609" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMN6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMN6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CRCBL", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMN6", "locus": {} } ], "crossref": [ { "id": "A0A8V0YMN6", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YMN6", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00063", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00063", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "771315", "url": "https://www.ncbi.nlm.nih.gov/gene/771315", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003961", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003961", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036116", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036116", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048668", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048668", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:771315", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:771315", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "LRFCGMY", "url": "https://omabrowser.org/oma/group/LRFCGMY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YMN6", "url": "https://www.orthodb.org/?gene=A0A8V0YMN6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23037", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23037", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23037:SF22", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23037:SF22", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00041", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00041", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21460", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21460", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_001234609", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001234609", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YMN6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMN6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YMN6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMN6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YU27", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YU27", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YU27-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YU27-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEGGLSECHSKTVQRLSSLIQFYFPLQEMKTRSSTVRQKEALAMKTFIFDKNICSKDSMKMMRGFFIFLLNLPVVFSDQAIKESVPMKSLRCHNDYKSLMTCTWKEHSEAHALLGLTLYHTRVTENVSEEMHCEKELGEDLHEASDPYTHWICGKTVKYFGIGVDDYYSFKPQQILEAHLEVHPFQNVQPLPPQNLSIRESSGDFLLTWTSPDGSQGLGSALEYEVAYKREWESWEKAASRLLSNTTRCHLSHLIPGSRYVARVRARPEQGRGFSGHYSEWSTDVSWETPEGGIHPRNLRCLFNGAYLMCSWEVKKVIATSVIFGLFFRPTPASVEKECSPVYEKNLPHVPYVVQSCGIPVSNISSRSQYQVSVRTKTEEKLIEAYKNIKVLPPANVSVELMKSQEYELRWKKHSLRYGFIKQKYQVQFWIHNQYEKTVQTINITNDEPPFIFTDQMLSPSAKYRGRMRAMVNNQDYQGYWSEWSEEFIWETENVLSPVVLPLMLPVIIITLLVVAYCSFKYFLRQKKLWEEKIPNPSKSLLIQSYLKKVSLGNRHASSQLDVNKCSLAENMDQPSFLQVVDRQTKTLAEPPEAQTERTEVSSAALDPQNPYHALNVPEHAPVVCPSQIPGHSFSVSRTNGADASITSQTAITCFAFNGPYLYSPVMSSQPEMHQTLEVTSNPMGKQEKAVSLQYVTLPDKASPQAAQRQEQPGAGPLQPFLLPDQKEVMRYLNDEKEVSPLPTTCEKSTDVRTEEQKSPEAPGCPTFLQQCPLEYITTDRLLLPSDSDTTHLPLVTAGGKPCDPQEPQLSSDCSCHEVSPGKFGVTLPPSGQISVSPEMHLDAFGDYLDVHSGLHGPSELSKISLPFQQKGSPLPKEQPLSEGNLVVLNPDSTEPVFLCQVGDYCFHSLKSGEKTCMSQGYPQIKKPSEGRTAPGKSVPDDESIIGKEADVSKMQAIQLFKSLKSDDYFSWQQSLRITEIC", "length": 982, "header": "tr|A0A8V0YMN6-1|A0A8V0YMN6_CHICK Isoform 1 of Fibronectin type-III domain-containing protein OS=Gallus gallus OX=9031 GN=CRCBL PE=4 SV=1 CANONICAL=A0A8V0YMN6-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YMN6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMN6/entry#A0A8V0YMN6-1", "sequence": { "sequence": "MEGGLSECHSKTVQRLSSLIQFYFPLQEMKTRSSTVRQKEALAMKTFIFDKNICSKDSMKMMRGFFIFLLNLPVVFSDQAIKESVPMKSLRCHNDYKSLMTCTWKEHSEAHALLGLTLYHTRVTENVSEEMHCEKELGEDLHEASDPYTHWICGKTVKYFGIGVDDYYSFKPQQILEAHLEVHPFQNVQPLPPQNLSIRESSGDFLLTWTSPDGSQGLGSALEYEVAYKREWESWEKAASRLLSNTTRCHLSHLIPGSRYVARVRARPEQGRGFSGHYSEWSTDVSWETPEGGIHPRNLRCLFNGAYLMCSWEVKKVIATSVIFGLFFRPTPASVEKECSPVYEKNLPHVPYVVQSCGIPVSNISSRSQYQVSVRTKTEEKLIEAYKNIKVLPPANVSVELMKSQEYELRWKKHSLRYGFIKQKYQVQFWIHNQYEKTVQTINITNDEPPFIFTDQMLSPSAKYRGRMRAMVNNQDYQGYWSEWSEEFIWETENVLSPVVLPLMLPVIIITLLVVAYCSFKYFLRQKKLWEEKIPNPSKSLLIQSYLKKVSLGNRHASSQLDVNKCSLAENMDQPSFLQVVDRQTKTLAEPPEAQTERTEVSSAALDPQNPYHALNVPEHAPVVCPSQIPGHSFSVSRTNGADASITSQTAITCFAFNGPYLYSPVMSSQPEMHQTLEVTSNPMGKQEKAVSLQYVTLPDKASPQAAQRQEQPGAGPLQPFLLPDQKEVMRYLNDEKEVSPLPTTCEKSTDVRTEEQKSPEAPGCPTFLQQCPLEYITTDRLLLPSDSDTTHLPLVTAGGKPCDPQEPQLSSDCSCHEVSPGKFGVTLPPSGQISVSPEMHLDAFGDYLDVHSGLHGPSELSKISLPFQQKGSPLPKEQPLSEGNLVVLNPDSTEPVFLCQVGDYCFHSLKSGEKTCMSQGYPQIKKPSEGRTAPGKSVPDDESIIGKEADVSKMQAIQLFKSLKSDDYFSWQQSLRITEIC", "length": 982, "header": "tr|A0A8V0YMN6-1|A0A8V0YMN6_CHICK Isoform 1 of Fibronectin type-III domain-containing protein OS=Gallus gallus OX=9031 GN=CRCBL PE=4 SV=1 CANONICAL=A0A8V0YMN6-1" }, "locus": { "chromosome": "1", "start_pos": 51612107, "end_pos": 51602233, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010038458.1", "url": "https://www.ensembl.org/id/ENSGALT00010038458.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010022244.1", "url": "https://www.ensembl.org/id/ENSGALP00010022244.1" } ] } }, { "isoform_ac": "A0A8V0YU27-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMN6/entry#A0A8V0YU27-1", "sequence": { "sequence": "MKTRSSTVRQKEALAMKTFIFDKNICSKDSMKMMRGFFIFLLNLPVVFSDQAIKESVPMKSLRCHNDYKSLMTCTWKEHSEAHALLGLTLYHTRVTENVSEEMHCEKELGEDLHEASDPYTHWICGKTVKYFGIGVDDYYSFKPQQILEAHLEVHPFQNVQPLPPQNLSIRESSGDFLLTWTSPDGSQGLGSALEYEVAYKREWESWEKAASRLLSNTTRCHLSHLIPGSRYVARVRARPEQGRGFSGHYSEWSTDVSWETPEGGIHPRNLRCLFNGAYLMCSWEVKKVIATSVIFGLFFRPTPASVEKECSPVYEKNLPHVPYVVQSCGIPVSNISSRSQYQVSVRTKTEEKLIEAYKNIKVLPPANVSVELMKSQEYELRWKKHSLRYGFIKQKYQVQFWIHNQYEKTVQTINITNDEPPFIFTDQMLSPSAKYRGRMRAMVNNQDYQGYWSEWSEEFIWETENVLSPVVLPLMLPVIIITLLVVAYCSFKYFLRQKKLWEEKIPNPSKSLLIQSYLKKVSLGNRHASSQLDVNKCSLAENMDQPSFLQVVDRQTKTLAEPPEAQTERTEVSSAALDPQNPYHALNVPEHAPVVCPSQIPGHSFSVSRTNGADASITSQTAITCFAFNGPYLYSPVMSSQPEMHQTLEVTSNPMGKQEKAVSLQYVTLPDKASPQAAQRQEQPGAGPLQPFLLPDQKEVMRYLNDEKEVSPLPTTCEKSTDVRTEEQKSPEAPGCPTFLQQCPLEYITTDRLLLPSDSDTTHLPLVTAGGKPCDPQEPQLSSDCSCHEVSPGKFGVTLPPSGQISVSPEMHLDAFGDYLDVHSGLHGPSELSKISLPFQQKGSPLPKEQPLSEGNLVVLNPDSTEPVFLCQVGDYCFHSLKSGEKTCMSQGYPQIKKPSEGRTAPGKSVPDDESIIGKEADVSKMQAIQLFKSLKSDDYFSWQQSLRITEIC", "length": 954, "header": "tr|A0A8V0YU27-1|A0A8V0YU27_CHICK Computationally mapped isoform of Fibronectin type-III domain-containing protein OS=Gallus gallus OX=9031 GN=CRCBL PE=4 SV=1 CANONICAL=A0A8V0YMN6-1" }, "locus": { "chromosome": "1", "start_pos": 51612023, "end_pos": 51602233, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010038453.1", "url": "https://www.ensembl.org/id/ENSGALT00010038453.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010022241.1", "url": "https://www.ensembl.org/id/ENSGALP00010022241.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:771315", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:771315", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "G3V608-1", "protein_name": "Colony stimulating factor 2 receptor subunit beta", "gene_name": "Csf2rb", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDQHMAFIWGLCYMALVALCWRHGVTKAEETVPLKTLQCYNDYIERIICSWADTEDAQGLVNLTLYHWLDKKQPMSCELSEDLMWSECPSSHRCVPRRCVLPYTQFSVSKEDYYSLQPDRDLSIHLVVPLAQHVQPPPPKDISISPSGDHFLLKWSVPHGDAQVSLLSQKDIQFEVAYKRLQDSWEDASSLHTSNLWVTLEPKLFLPNSIYVARVRTQLAPGSSLSGRPSRWSPEVHWDSPTGDKARPQNLQCFFDGIQSLNCSWEVWTKVTDSVSFGLFYSSSPKAGEKKCSPVVKELQASRYTRYHCSLNVSDPAAHSQYTVSVKRLEQGKFIESFNHIQMNPPTLNLTKNRDSYSLHWETQKMSYPFIQHAFQVQYKKKLDSWEDSKTENLNHAHSMDLPQLEPGTSYCARVRVKTIPEYKGLWSEWSNECTWTTDWVMPTLWIVLILVFLILTFLLALRFGCIYGCKLYRKWKEKIPNPSKSLLFQDGGKGLWPPGSTVTFSSKNPTPQGPQSNLFSELQGVSYTHLEDNEVSPLTIEDPNIIRDPSSGPDTTPAASSEPMEQSSNVQVDPPTLSGRPRKQLPSFDFNGPYLGPPQSHSLPDLPGQLVSPQGGGSLKPALPGSLEYMCLPPGGQVQLVPLSQVMGQGRDVDVQCGSSLETTESPSMESRESPPVELKEEEQEPRDNPVTLPISSGGPKDSKVASEYVTPADLVLTLPTEPLSTSLGPSLEVSSAQSPSLCLKLPRVPSESPALAPAVFEDYVELPPSMSQPAKSLPGNPAPPGPSSPAVSPGEPREEVGAAPTHPEGLLVLQQVGDYCFLPGLGPSPLSPPSKPPSPGLCLETEDLDKDLSVKKLPYQPIPQVPAIQFFKSLKHQDYLSLPPWDNSQPGKVC", "length": 896 }, "evidence": [ { "id": "A0A8V0YMN6", "url": "https://omabrowser.org/oma/group/A0A8V0YMN6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P26955-1", "protein_name": "Cytokine receptor common subunit beta", "gene_name": "Csf2rb", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDQQMALTWGLCYMALVALCWGHGVTEAEETVPLKTLQCYNDYTNHIICSWADTEDAQGLINMTLYHQLEKKQPVSCELSEELMWSECPSSHRCVPRRCVIPYTRFSITNEDYYSFRPDSDLGIQLMVPLAQNVQPPLPKNVSISSSEDRFLLEWSVSLGDAQVSWLSSKDIEFEVAYKRLQDSWEDAYSLHTSKFQVNFEPKLFLPNSIYAARVRTRLSPGSSLSGRPSRWSPEVHWDSQPGDKAQPQNLQCFFDGIQSLHCSWEVWTQTTGSVSFGLFYRPSPVAPEEKCSPVVKEPPGASVYTRYHCSLPVPEPSAHSQYTVSVKHLEQGKFIMSYNHIQMEPPTLNLTKNRDSYSLHWETQKMAYSFIEHTFQVQYKKKSDSWEDSKTENLDRAHSMDLSQLEPDTSYCARVRVKPISNYDGIWSKWSEEYTWKTDWVMPTLWIVLILVFLILTLLLILRFGCVSVYRTYRKWKEKIPNPSKSLLFQDGGKGLWPPGSMAAFATKNPALQGPQSRLLAEQQGESYAHLEDNNVSPLTIEDPNIIRVPPSGPDTTPAASSESTEQLPNVQVEGPTPNRPRKQLPSFDFNGPYLGPPQSHSLPDLPDQLGSPQVGGSLKPALPGSLEYMCLPPGGQAQLVPLSQVMGQGQAMDVQCGSSLETSGSPSVEPKENPPVELSMEEQEARDNPVTLPISSGGPEGSMMASDYVTPGDPVLTLPTGPLSTSLGPSLGLPSAQSPSLCLKLPRVPSGSPALGPPGFEDYVELPPSVSQAAKSPPGHPAPPVASSPTVIPGEPREEVGPASPHPEGLLVLQQVGDYCFLPGLGPGSLSPHSKPPSPSLCSETEDLVQDLSVKKFPYQPMPQAPAIQFFKSLKHQDYLSLPPWDNSQSGKVC", "length": 896 }, "evidence": [ { "id": "A0A8V0YMN6", "url": "https://omabrowser.org/oma/group/A0A8V0YMN6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P32927-1", "protein_name": "Cytokine receptor common subunit beta", "gene_name": "CSF2RB", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVLAQGLLSMALLALCWERSLAGAEETIPLQTLRCYNDYTSHITCRWADTQDAQRLVNVTLIRRVNEDLLEPVSCDLSDDMPWSACPHPRCVPRRCVIPCQSFVVTDVDYFSFQPDRPLGTRLTVTLTQHVQPPEPRDLQISTDQDHFLLTWSVALGSPQSHWLSPGDLEFEVVYKRLQDSWEDAAILLSNTSQATLGPEHLMPSSTYVARVRTRLAPGSRLSGRPSKWSPEVCWDSQPGDEAQPQNLECFFDGAAVLSCSWEVRKEVASSVSFGLFYKPSPDAGEEECSPVLREGLGSLHTRHHCQIPVPDPATHGQYIVSVQPRRAEKHIKSSVNIQMAPPSLNVTKDGDSYSLRWETMKMRYEHIDHTFEIQYRKDTATWKDSKTETLQNAHSMALPALEPSTRYWARVRVRTSRTGYNGIWSEWSEARSWDTESVLPMWVLALIVIFLTIAVLLALRFCGIYGYRLRRKWEEKIPNPSKSHLFQNGSAELWPPGSMSAFTSGSPPHQGPWGSRFPELEGVFPVGFGDSEVSPLTIEDPKHVCDPPSGPDTTPAASDLPTEQPPSPQPGPPAASHTPEKQASSFDFNGPYLGPPHSRSLPDILGQPEPPQEGGSQKSPPPGSLEYLCLPAGGQVQLVPLAQAMGPGQAVEVERRPSQGAAGSPSLESGGGPAPPALGPRVGGQDQKDSPVAIPMSSGDTEDPGVASGYVSSADLVFTPNSGASSVSLVPSLGLPSDQTPSLCPGLASGPPGAPGPVKSGFEGYVELPPIEGRSPRSPRNNPVPPEAKSPVLNPGERPADVSPTSPQPEGLLVLQQVGDYCFLPGLGPGPLSLRSKPSSPGPGPEIKNLDQAFQVKKPPGQAVPQVPVIQLFKALKQQDYLSLPPWEVNKPGEVC", "length": 897 }, "evidence": [ { "id": "A0A8V0YMN6", "url": "https://omabrowser.org/oma/group/A0A8V0YMN6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "interleukin-5-mediated signaling pathway", "id": "GO:0038043", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038043", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMN6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMN6" } ], "pmid": "" }, { "name": "interleukin-3-mediated signaling pathway", "id": "GO:0038156", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038156", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMN6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMN6" } ], "pmid": "" }, { "name": "immunoglobulin mediated immune response", "id": "GO:0016064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016064", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMN6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMN6" } ], "pmid": "" }, { "name": "cell surface receptor signaling pathway via JAK-STAT", "id": "GO:0007259", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007259", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMN6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMN6" } ], "pmid": "" }, { "name": "positive regulation of leukocyte proliferation", "id": "GO:0070665", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070665", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMN6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMN6" } ], "pmid": "" }, { "name": "granulocyte-macrophage colony-stimulating factor signaling pathway", "id": "GO:0038157", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038157", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMN6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMN6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "external side of plasma membrane", "id": "GO:0009897", "url": 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"https://www.ebi.ac.uk/interpro/entry/IPR050149", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050938", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050938", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YMR4", "url": "https://www.orthodb.org/?gene=A0A8V0YMR4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YMR9", "url": "https://www.orthodb.org/?gene=A0A8V0YMR9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YPS5", "url": "https://www.orthodb.org/?gene=A0A8V0YPS5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YUS9", "url": "https://www.orthodb.org/?gene=A0A8V0YUS9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YUT4", "url": "https://www.orthodb.org/?gene=A0A8V0YUT4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24023", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24023", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24023:SF1034", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24023:SF1034", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24023:SF1060", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24023:SF1060", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24023:SF1118", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24023:SF1118", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR37456", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR37456", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR37456:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR37456:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01391", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01391", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01392", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01392", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF06482", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06482", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF20010", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF20010", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-1442490", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1442490", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-1592389", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1592389", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-1650814", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1650814", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-216083", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-216083", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-8948216", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8948216", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YMR4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMR4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YMR4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMR4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YMR9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMR9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YMR9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMR9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YPS5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPS5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YPS5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPS5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YUS9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUS9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YUS9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUS9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YUT4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUT4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YUT4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUT4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRALQAPRWGQAPTSAPDPLCLRSQGARFPLPMALLHLGLWLLLASCCFSSSDAQLLDWIWGRPKTTGTPTAPSTAETLPTLSTPLSSAAAGDVATTQRRWEPEPSMAVPTGEESTESTDGTEQGDRSTAGITLPTGTAWTATPPRSTSPTHSPTETPLPLGTGNPNTTELPQQQEGAGGSPQRPAAARPGRAPFPFPSGDSAHHPTAQRHGASPTPRAADRAGTRGWGPWATPRPSPAAPSAATPGDGDPKRSTNGKGLALLGVSGSQSPSAPKLRAVSGVDSPPAGPPEFDLLTSTLRVVGAGLAPSFPRLLPAGGRCLPLPAHLPFCSVLGTSHLRLPNYLSHGSEAEIWAALHEWEGLLVSRCHRYLEWFLCLLLVPGCSALVPVTPPPCQGFCEAVRDLCWMHSAGGHLPLPCDSLPKEDGGYSCVFVNVSAENLSTEVSLLELIGDPPPEEILKIYGPDNNPGYVFGPSANTGQVARYHLPSPFYRDFSLLFHIQPTTPRAGMLFAITDSTQSIIYVGVKLSDLQMGKQQIIFYYTEPGSQSSYAAATFTVPTLLNQWTRFAISVEEDEVILYLDCEEHERVRFERSPDEMELEEGSGLFVAQAGGADPDKYQGVIADLRLRGDPRAAEHQCEEEEDDAEASGDFGSGAEDRHHPSGKDKGIPGLLDAVPVTSPPVVEGSGTRSSAGSPQQAERTRVEERLQVSTGGTGPKGEKGEKGERGPKGDSGTSGILGTGATKGEKGEKGELGIKGSAGFGYPGSKGQKGEPGEPGPPGPLSRHTDSMSLEQVTGPPGPTGPPGKDGAPGRDGEPGDPGEDGKPGEMGPQGFPGTPGESGQKGEKGDPGVGPRGPPGPPGPPGPPGRSSKQDGLTFIDMEGSGFGGDLETLRGPRGPPGPPGPPGVPGLPGEPGRFGMNSTDLPGPPGLPGRDGTPGAPGPEGPLGPPGKDGMPGPPGPKGERGDVGDLGLPGAPGPKGSKGEAGPAGPPGETGLAGLPGPVGPRGPPGPPGPPGPPGPGYEAGFGDMEGSGLPLATGSPGPRGPSGPQGVPGLPGIKGEVGSLGQPGPPGPKGDAGVPGVDGRPGLEGFPGPQGPKGNRGSPGEKGERGQDGVGLPGPPGPPGPPGQVIYMSSEDRPLVALPGPEGRSGHAGFPGPVGPKGDPGSPGIQGAPGIKGEKGEPGVIISPDGTIVAANVKGQKGEPGLPGPMGPSGPHGRAGMKGEIGFPGRPGRPGMNGLKGEKGDPVDISSVLSLRGPPGPPGPPGPPGPPGSVVYDSNNGFSDASRPAFPGFHQFPGQKGEKGDVGAPGPPGQFPYDLSRFSASLRGDKGEAGPKGEKGEPGSSTLYGPSVTGPPGPQGYPGPPGPKGDSIVGPPGPPGPQGPPGIGYEGRQGPPGPPGPPGPPSFPGPHRQAISIPGPPGPPGPPGPPGTSGTSLGLRTMPTYQAMLSAAHELPEGGLIFLADRQELYIRLRGGFRRVLLEEHTLVPSSALDNEVYDKLPSIHYGGAQQPVHPLRNHNPPPTARPWRGDEVVANQHHLPQPPLLQQHELLNSYYIHRWPDPAPVAAHVHQDFQPALHLVALNTPLSGGMRGIRGADFQCFQQARQVGLAGTFRAFLSSRLQDLYSIVRRADRTAVPIVNLRDEVLFSNWEALFTGSEAPLRAGARILSFDGRDILQDSAWPQKSIWHGSDAKGRRLPESYCEAWRTDERGTSGQASSLSSGKLLEQSASSCQHAFVVLCIENSFMTAAKK", "length": 1753, "header": "tr|A0A8V0YMR4-1|A0A8V0YMR4_CHICK Isoform 1 of Collagen alpha-1(XVIII) chain OS=Gallus gallus OX=9031 GN=COL18A1 PE=1 SV=1 CANONICAL=A0A8V0YMR4-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YMR4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMR4/entry#A0A8V0YMR4-1", "sequence": { "sequence": "MRALQAPRWGQAPTSAPDPLCLRSQGARFPLPMALLHLGLWLLLASCCFSSSDAQLLDWIWGRPKTTGTPTAPSTAETLPTLSTPLSSAAAGDVATTQRRWEPEPSMAVPTGEESTESTDGTEQGDRSTAGITLPTGTAWTATPPRSTSPTHSPTETPLPLGTGNPNTTELPQQQEGAGGSPQRPAAARPGRAPFPFPSGDSAHHPTAQRHGASPTPRAADRAGTRGWGPWATPRPSPAAPSAATPGDGDPKRSTNGKGLALLGVSGSQSPSAPKLRAVSGVDSPPAGPPEFDLLTSTLRVVGAGLAPSFPRLLPAGGRCLPLPAHLPFCSVLGTSHLRLPNYLSHGSEAEIWAALHEWEGLLVSRCHRYLEWFLCLLLVPGCSALVPVTPPPCQGFCEAVRDLCWMHSAGGHLPLPCDSLPKEDGGYSCVFVNVSAENLSTEVSLLELIGDPPPEEILKIYGPDNNPGYVFGPSANTGQVARYHLPSPFYRDFSLLFHIQPTTPRAGMLFAITDSTQSIIYVGVKLSDLQMGKQQIIFYYTEPGSQSSYAAATFTVPTLLNQWTRFAISVEEDEVILYLDCEEHERVRFERSPDEMELEEGSGLFVAQAGGADPDKYQGVIADLRLRGDPRAAEHQCEEEEDDAEASGDFGSGAEDRHHPSGKDKGIPGLLDAVPVTSPPVVEGSGTRSSAGSPQQAERTRVEERLQVSTGGTGPKGEKGEKGERGPKGDSGTSGILGTGATKGEKGEKGELGIKGSAGFGYPGSKGQKGEPGEPGPPGPLSRHTDSMSLEQVTGPPGPTGPPGKDGAPGRDGEPGDPGEDGKPGEMGPQGFPGTPGESGQKGEKGDPGVGPRGPPGPPGPPGPPGRSSKQDGLTFIDMEGSGFGGDLETLRGPRGPPGPPGPPGVPGLPGEPGRFGMNSTDLPGPPGLPGRDGTPGAPGPEGPLGPPGKDGMPGPPGPKGERGDVGDLGLPGAPGPKGSKGEAGPAGPPGETGLAGLPGPVGPRGPPGPPGPPGPPGPGYEAGFGDMEGSGLPLATGSPGPRGPSGPQGVPGLPGIKGEVGSLGQPGPPGPKGDAGVPGVDGRPGLEGFPGPQGPKGNRGSPGEKGERGQDGVGLPGPPGPPGPPGQVIYMSSEDRPLVALPGPEGRSGHAGFPGPVGPKGDPGSPGIQGAPGIKGEKGEPGVIISPDGTIVAANVKGQKGEPGLPGPMGPSGPHGRAGMKGEIGFPGRPGRPGMNGLKGEKGDPVDISSVLSLRGPPGPPGPPGPPGPPGSVVYDSNNGFSDASRPAFPGFHQFPGQKGEKGDVGAPGPPGQFPYDLSRFSASLRGDKGEAGPKGEKGEPGSSTLYGPSVTGPPGPQGYPGPPGPKGDSIVGPPGPPGPQGPPGIGYEGRQGPPGPPGPPGPPSFPGPHRQAISIPGPPGPPGPPGPPGTSGTSLGLRTMPTYQAMLSAAHELPEGGLIFLADRQELYIRLRGGFRRVLLEEHTLVPSSALDNEVYDKLPSIHYGGAQQPVHPLRNHNPPPTARPWRGDEVVANQHHLPQPPLLQQHELLNSYYIHRWPDPAPVAAHVHQDFQPALHLVALNTPLSGGMRGIRGADFQCFQQARQVGLAGTFRAFLSSRLQDLYSIVRRADRTAVPIVNLRDEVLFSNWEALFTGSEAPLRAGARILSFDGRDILQDSAWPQKSIWHGSDAKGRRLPESYCEAWRTDERGTSGQASSLSSGKLLEQSASSCQHAFVVLCIENSFMTAAKK", "length": 1753, "header": "tr|A0A8V0YMR4-1|A0A8V0YMR4_CHICK Isoform 1 of Collagen alpha-1(XVIII) chain OS=Gallus gallus OX=9031 GN=COL18A1 PE=1 SV=1 CANONICAL=A0A8V0YMR4-1" }, "locus": { "chromosome": "7", "start_pos": 6714881, "end_pos": 6699157, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034043.1", "url": "https://www.ensembl.org/id/ENSGALT00010034043.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020008.1", "url": "https://www.ensembl.org/id/ENSGALP00010020008.1" } ] } }, { "isoform_ac": "A0A8V0YMR9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMR4/entry#A0A8V0YMR9-1", "sequence": { "sequence": "MRPGCAPRRLLLLGLFVLLLLPAASQEPENLSTEVSLLELIGDPPPEEILKIYGPDNNPGYVFGPSANTGQVARYHLPSPFYRDFSLLFHIQPTTPRAGMLFAITDSTQSIIYVGVKLSDLQMGKQQIIFYYTEPGSQSSYAAATFTVPTLLNQWTRFAISVEEDEVILYLDCEEHERVRFERSPDEMELEEGSGLFVAQAGGADPDKYQGVIADLRLRGDPRAAEHQCEEEEDDAEASGDFGSGAEDRHHPSGKDKGIPGLLDAVPVTSPPVVEGSGTRSSAGSPQQAERTRVEERLQVSTGGTGPKGEKGEKGERGPKGDSGTSGILGTGATKGEKGSAGFGYPGSKGQKGEPGEPGPPGPLSRHTDSMSLEQVTGPPGPTGPPGKDGAPGRDGEPGDPGEDGKPGEMGPQGFPGTPGESGQKGEKGDPGVGPRGPPGPPGPPGPPGRSSKQDGLGPRGPPGPPGPPGVPGLPGEPGRFGMNSTDLPGPPGLPGRDGTPGAPGPEGPLGPPGKDGMPGPPGPKGERGDVGDLGLPGAPGPKGSKGEAGPAGPPGETGLAGLPGPVGPRGPPGPPGPPGPPGPGYEAGFGDMEGSGLPLATGSPGPRGPSGPQGVPGLPGIKGEVGSLGQPGPPGPKGDAGVPGVDGRPGLEGFPGPQGPKGNRGSPGEKGERGQDGVGLPGPPGPPGPPGQVIYMSSEDRPLVALPGPEGRSGHAGFPGPVGPKGDPGSPGIQGAPGIKGEKGEPGVIISPDGTIVAANVKGQKGEPGLPGPMGPSGPHGRAGMKGEIGFPGRPGRPGMNGLKGEKGDPVDISSVLSLRGPPGPPGPPGPPGPPGSVVYDSNNGFSDASRPAFPGFHQFPGQKGEKGDVGAPGPPGQFPYDLSRFSASLRGDKGEAGPKGEKGEPGSSTLYGPSVTGPPGPQGYPGPPGPKGDSIVGPPGPPGPQGPPGIGYEGRQGPPGPPGPPGPPSFPGPHRQAISIPGPPGPPGPPGPPGTSGTSLGLRTMPTYQAMLSAAHELPEGGLIFLADRQELYIRLRGGFRRVLLEEHTLVPSSALDNEVYDKLPSIHYGGAQQPVHPLRNHNPPPTARPWRGDEVVANQHHLPQPPLLQQHELLNSYYIHRWPDPAPVAAHVHQDFQPALHLVALNTPLSGGMRGIRGADFQCFQQARQVGLAGTFRAFLSSRLQDLYSIVRRADRTAVPIVNLRDEVLFSNWEALFTGSEAPLRAGARILSFDGRDILQDSAWPQKSIWHGSDAKGRRLPESYCEAWRTDERGTSGQASSLSSGKLLEQSASSCQHAFVVLCIENSFMTAAKK", "length": 1317, "header": "tr|A0A8V0YMR9-1|A0A8V0YMR9_CHICK Computationally mapped isoform of Collagen, type XVIII, alpha 1 OS=Gallus gallus OX=9031 GN=COL18A1 PE=1 SV=1 CANONICAL=A0A8V0YMR4-1" }, "locus": { "chromosome": "7", "start_pos": 6714881, "end_pos": 6685061, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034050.1", "url": "https://www.ensembl.org/id/ENSGALT00010034050.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020013.1", "url": "https://www.ensembl.org/id/ENSGALP00010020013.1" } ] } }, { "isoform_ac": "A0A8V0YPS5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMR4/entry#A0A8V0YPS5-1", "sequence": { "sequence": "MRPGCAPRRLLLLGLFVLLLLPAASQEPENLSTEVSLLELIGDPPPEEILKIYGPDNNPGYVFGPSANTGQVARYHLPSPFYRDFSLLFHIQPTTPRAGMLFAITDSTQSIIYVGVKLSDLQMGKQQIIFYYTEPGSQSSYAAATFTVPTLLNQWTRFAISVEEDEVILYLDCEEHERVRFERSPDEMELEEGSGLFVAQAGGADPDKYQGVIADLRLRGDPRAAEHQCEEEEDDAEASGDFGSGAEDRHHPSGKDKGIPGLLDAVPVTSPPVVEGSGTRSSAGSPQQAERTRVEERLQVSTGGTGPKGEKGEKGERGPKGDSGTSGILGTGATKGEKGEKGELGIKGSAGFGYPGSKGQKGEPGEPGPPGPLSRHTDSMSLEQVTGPPGPTGPPGKDGAPGRDGEPGDPGEDGKPGEMGPQGFPGTPGESGQKGEKGDPGVGPRGPPGPPGPPGPPGRSSKQDGLTFIDMEGSGFGGDLETLRGPRGPPGPPGETGLAGLPGPVGPRGPPGPPGPPGPPGPGYEAGFGDMEGSGLPLATGSPGPRGPSGPQGVPGLPGIKGEVGSLGQPGPPGPKGDAGVPGVDGRPGLEGFPGPQGPKGNRGSPGEKGERGQDGVGLPGPPGPPGPPGQVIYMSSEDRPLVALPGPEGRSGHAGFPGPVGPKGDPGSPGIQGAPGIKGEKGEPGVIISPDGTIVAANVKGQKGEPGLPGPMGPSGPHGRAGMKGEIGFPGRPGRPGMNGLKGEKGDPVDISSVLSLRGPPGPPGPPGPPGPPGSVVYDSNNGFSDASRPAFPGFHQFPGQKGEKGDVGAPGPPGQFPYDLSRFSASLRGDKGEAGPKGEKGEPGSSTLYGPSVTGPPGPQGYPGPPGPKGDSIVGPPGPPGPQGPPGIGYEGRQGPPGPPGPPGPPSFPGPHRQAISIPGPPGPPGPPGPPGTSGTSLGLRTMPTYQAMLSAAHELPEGGLIFLADRQELYIRLRGGFRRVLLEEHTLVPSSALDNEVYDKLPSIHYGGAQQPVHPLRNHNPPPTARPWRGDEVVANQHHLPQPPLLQQHELLNSYYIHRWPDPAPVAAHVHQDFQPALHLVALNTPLSGGMRGIRGADFQCFQQARQVGLAGTFRAFLSSRLQDLYSIVRRADRTAVPIVNLRDEVLFSNWEALFTGSEAPLRAGARILSFDGRDILQDSAWPQKSIWHGSDAKGRRLPESYCEAWRTDERGTSGQASSLSSGKLLEQSASSCQHAFVVLCIENSFMTAAKK", "length": 1255, "header": "tr|A0A8V0YPS5-1|A0A8V0YPS5_CHICK Computationally mapped isoform of Collagen, type XVIII, alpha 1 OS=Gallus gallus OX=9031 GN=COL18A1 PE=1 SV=1 CANONICAL=A0A8V0YMR4-1" }, "locus": { "chromosome": "7", "start_pos": 6714881, "end_pos": 6685061, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034061.1", "url": "https://www.ensembl.org/id/ENSGALT00010034061.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020017.1", "url": "https://www.ensembl.org/id/ENSGALP00010020017.1" } ] } }, { "isoform_ac": "A0A8V0YUS9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMR4/entry#A0A8V0YUS9-1", "sequence": { "sequence": "MRPGCAPRRLLLLGLFVLLLLPAASQEPENLSTEVSLLELIGDPPPEEILKIYGPDNNPGYVFGPSANTGQVARYHLPSPFYRDFSLLFHIQPTTPRAGMLFAITDSTQSIIYVGVKLSDLQMGKQQIIFYYTEPGSQSSYAAATFTVPTLLNQWTRFAISVEEDEVILYLDCEEHERVRFERSPDEMELEEGSGLFVAQAGGADPDKYQGVIADLRLRGDPRAAEHQCEEEEDDAEASGDFGSGAEDRHHPSGKDKGIPGLLDAVPVTSPPVVEGSGTRSSAGSPQQAERTRVEERLQVSTGGTGPKGEKGEKGERGPKGDSGTSGILGTGATKGEKGEKGELGIKGSAGFGYPGSKGQKGEPGEPGPPGPLSRHTDSMSLEQVTGPPGPTGPPGKDGAPGRDGEPGDPGEDGKPGEMGPQGFPGTPGESGQKGEKGDPGVGPRGPPGPPGPPGPPGRSSKQDGLTFIDMEGSGFGGDLETLRGPRGPPGPPGPPGVPGLPGEPGRFGMNSTDLPGLPGIKGEVGSLGQPGPPGPKGDAGVPGVDGRPGLEGFPGPQGPKGNRGSPGEKGERGQDGVGLPGPPGPPGPPGQVIYMSSEDRPLVALPGPEGRSGHAGFPGPVGPKGDPGSPGIQGAPGIKGEKGEPGVIISPDGTIVAANVKGQKGEPGLPGPMGPSGPHGRAGMKGEIGFPGRPGRPGMNGLKGEKGDPVDISSVLSLRGPPGPPGPPGPPGPPGSVVYDSNNGFSDASRPAFPGFHQFPGQKGEKGDVGAPGPPGQFPYDLSRFSASLRGDKGEAGPKGEKGEPGSSTLYGPSVTGPPGPQGYPGPPGPKGDSIVGPPGPPGPQGPPGIGYEGRQGPPGPPGPPGPPSFPGPHRQAISIPGPPGPPGPPGPPGTSGTSLGLRTMPTYQAMLSAAHELPEGGLIFLADRQELYIRLRGGFRRVLLEEHTLVPSSALDNEVYDKLPSIHYGGAQQPVHPLRNHNPPPTARPWRGDEVVANQHHLPQPPLLQQHELLNSYYIHRWPDPAPVAAHVHQDFQPALHLVALNTPLSGGMRGIRGADFQCFQQARQVGLAGTFRAFLSSRLQDLYSIVRRADRTAVPIVNLRDEVLFSNWEALFTGSEAPLRAGARILSFDGRDILQDSAWPQKSIWHGSDAKGRRLPESYCEAWRTDERGTSGQASSLSSGKLLEQSASSCQHAFVVLCIENSFMTAAKK", "length": 1216, "header": "tr|A0A8V0YUS9-1|A0A8V0YUS9_CHICK Computationally mapped isoform of Collagen, type XVIII, alpha 1 OS=Gallus gallus OX=9031 GN=COL18A1 PE=1 SV=1 CANONICAL=A0A8V0YMR4-1" }, "locus": { "chromosome": "7", "start_pos": 6714881, "end_pos": 6685061, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034054.1", "url": "https://www.ensembl.org/id/ENSGALT00010034054.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020015.1", "url": "https://www.ensembl.org/id/ENSGALP00010020015.1" } ] } }, { "isoform_ac": "A0A8V0YUT4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMR4/entry#A0A8V0YUT4-1", "sequence": { "sequence": 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Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015138406", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015138406" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YML2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YML2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CCNE2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YML2", "locus": { "chromosome": "2", "start_pos": 125964119, "end_pos": 125977970, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012428", "url": "https://www.ensembl.org/id/ENSGALG00010012428" } ] } } ], "crossref": [ { "id": "A0A8V0YML2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YML2", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd20580", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd20580", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd20582", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd20582", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "420231", "url": "https://www.ncbi.nlm.nih.gov/gene/420231", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004367", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004367", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006671", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006671", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013763", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013763", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036915", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036915", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039361", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039361", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048258", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048258", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "WPPTISG", "url": "https://omabrowser.org/oma/group/WPPTISG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y9G0", "url": "https://www.orthodb.org/?gene=A0A8V0Y9G0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YEJ9", "url": "https://www.orthodb.org/?gene=A0A8V0YEJ9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YHU5", "url": "https://www.orthodb.org/?gene=A0A8V0YHU5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YML2", "url": "https://www.orthodb.org/?gene=A0A8V0YML2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10177", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10177", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00134", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00134", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02984", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02984", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-1538133", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1538133", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-187577", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-187577", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-2559586", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2559586", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-6804116", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6804116", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-69017", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-69017", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-69200", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-69200", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-69202", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-69202", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-69231", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-69231", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-69563", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-69563", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_015138406", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015138406", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Y9G0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9G0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y9G0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9G0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YEJ9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEJ9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YEJ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEJ9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHU5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHU5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHU5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHU5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YML2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YML2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YML2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YML2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSRRSSRLQAKQQQQPPLPCQEETPRELQAPEHLQTRKRRTAEQEIKKKEDGKIAKKHQYEIKSCWPPTITGGISPCIIIETPHKESVTTDFSRFKKYRFRNLFINPSPLPELTWGNSKDVWLNILKKENRYAHCKHFTSLHSSLQPHMRSILLDWLLEVCEVYALHRETFYLAQDFFDRFMLTQKNINKSMLQLIGITSLFIASKLEEIYAPKIQEFAYVTDGACSEDDIVRMELIMLKALKWELCPVTIISWLNLYLQVDALKDVPKVLLPQYSQEKFIQIAQLLDLCILDVNSLDFQYRTLAAAALCHYTSTEVVKKASGLDWDNISECVEWMVPFVNVARKVSVKLKHFKKVAVEDCHNIQTHTNYLDMLEEVNSGVASTAPGQLSPVSTAGIITPPKSTEKK", "length": 407, "header": "tr|A0A8V0YML2-1|A0A8V0YML2_CHICK Isoform 1 of Cyclin E2 OS=Gallus gallus OX=9031 GN=CCNE2 PE=3 SV=1 CANONICAL=A0A8V0YML2-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Y9G0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YML2/entry#A0A8V0Y9G0-1", "sequence": { "sequence": "MGERGGCGGGSAGRRCGAAGVERSYRPKMSRRSSRLQAKQQQQPPLPCQEETPRELQAPEHLQTRKRRTAEQEIKKKEDGKIAKKHQYEIKSCWPPTITGGISPCIIIETPHKESVTTDFSRFKKYRFRNLFINPSPLPELTWGNSKDVWLNILKKENRYAHCKHFTSLHSSLQPHMRSILLDWLLEVCEVYALHRETFYLAQDFFDRFMLTQKNINKSMLQLIGITSLFIASKLEEIYAPKIQEFAYVTDGACSEDDIVRMELIMLKALKWELCPVTIISWLNLYLQVDALKDVPKVLLPQYSQEKFIQIAQLLDLCILDVNSLDFQYRTLAAAALCHYTSTEVVKKASGLDWDNISECVEWMVPFVNVARKVSVKLKHFKKVAVEDCHNIQTHTNYLDMLEEVNSGVASTAPGQLSPVSTAGIITPPKSTEKK", "length": 435, "header": "tr|A0A8V0Y9G0-1|A0A8V0Y9G0_CHICK Computationally mapped isoform of Cyclin E2 OS=Gallus gallus OX=9031 GN=CCNE2 PE=3 SV=1 CANONICAL=A0A8V0YML2-1" }, "locus": { "chromosome": "2", "start_pos": 125976831, "end_pos": 125965443, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029807.1", "url": "https://www.ensembl.org/id/ENSGALT00010029807.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017354.1", "url": "https://www.ensembl.org/id/ENSGALP00010017354.1" } ] } }, { "isoform_ac": "A0A8V0YEJ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YML2/entry#A0A8V0YEJ9-1", "sequence": { "sequence": "MCSISWIQKVLCRELNACDVQCYHLEDNLFVLQSCWPPTITGGISPCIIIETPHKESVTTDFSRFKKYRFRNLFINPSPLPELTWGNSKDVWLNILKKENRYAHCKHFTSLHSSLQPHMRSILLDWLLEVCEVYALHRETFYLAQDFFDRFMLTQKNINKSMLQLIGITSLFIASKLEEIYAPKIQEFAYVTDGACSEDDIVRMELIMLKALKWELCPVTIISWLNLYLQVDALKDVPKVLLPQYSQEKFIQIAQLLDLCILDVNSLDFQYRTLAAAALCHYTSTEVVKKASGLDWDNISECVEWMVPFVNVARKVSVKLKHFKKVAVEDCHNIQTHTNYLDMLEEVNSGVASTAPGQLSPVSTAGIITPPKSTEKK", "length": 377, "header": "tr|A0A8V0YEJ9-1|A0A8V0YML2_CHICK Computationally mapped isoform of Cyclin E2 OS=Gallus gallus OX=9031 GN=CCNE2 PE=3 SV=1 CANONICAL=A0A8V0YML2-1" }, "locus": { "chromosome": "2", "start_pos": 125973691, "end_pos": 125965443, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029794.1", "url": "https://www.ensembl.org/id/ENSGALT00010029794.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017348.1", "url": "https://www.ensembl.org/id/ENSGALP00010017348.1" } ] } }, { "isoform_ac": "A0A8V0YHU5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YML2/entry#A0A8V0YHU5-1", "sequence": { "sequence": "MASLPAQPPFKKEKKERSYRPKMSRRSSRLQAKQQQQPPLPCQEETPRELQAPEHLQTRKRRTAEEIKKKEDGKIAKKHQYEIKSCWPPTITGGISPCIIIETPHKESVTTDFSRFKKYRFRNLFINPSPLPELTWGNSKDVWLNILKKENRYAHCKHFTSLHSSLQPHMRSILLDWLLEVCEVYALHRETFYLAQDFFDRFMLTQKNINKSMLQLIGITSLFIASKLEEIYAPKIQEFAYVTDGACSEDDIVRMELIMLKALKWELCPVTIISWLNLYLQVDALKDVPKVLLPQYSQEKFIQIAQLLDLCILDVNSLDFQYRTLAAAALCHYTSTEVVKKASGLDWDNISECVEWMVPFVNVARKVSVKLKHFKKVAVEDCHNIQTHTNYLDMLEEVNSGVASTAPGQLSPVSTAGIITPPKSTEKK", "length": 428, "header": "tr|A0A8V0YHU5-1|A0A8V0YML2_CHICK Computationally mapped isoform of Cyclin E2 OS=Gallus gallus OX=9031 GN=CCNE2 PE=3 SV=1 CANONICAL=A0A8V0YML2-1" }, "locus": { "chromosome": "2", "start_pos": 125977843, "end_pos": 125965443, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029817.1", "url": "https://www.ensembl.org/id/ENSGALT00010029817.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017362.1", "url": "https://www.ensembl.org/id/ENSGALP00010017362.1" } ] } }, { "isoform_ac": "A0A8V0YML2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YML2/entry#A0A8V0YML2-1", "sequence": { "sequence": "MSRRSSRLQAKQQQQPPLPCQEETPRELQAPEHLQTRKRRTAEQEIKKKEDGKIAKKHQYEIKSCWPPTITGGISPCIIIETPHKESVTTDFSRFKKYRFRNLFINPSPLPELTWGNSKDVWLNILKKENRYAHCKHFTSLHSSLQPHMRSILLDWLLEVCEVYALHRETFYLAQDFFDRFMLTQKNINKSMLQLIGITSLFIASKLEEIYAPKIQEFAYVTDGACSEDDIVRMELIMLKALKWELCPVTIISWLNLYLQVDALKDVPKVLLPQYSQEKFIQIAQLLDLCILDVNSLDFQYRTLAAAALCHYTSTEVVKKASGLDWDNISECVEWMVPFVNVARKVSVKLKHFKKVAVEDCHNIQTHTNYLDMLEEVNSGVASTAPGQLSPVSTAGIITPPKSTEKK", "length": 407, "header": "tr|A0A8V0YML2-1|A0A8V0YML2_CHICK Isoform 1 of Cyclin E2 OS=Gallus gallus OX=9031 GN=CCNE2 PE=3 SV=1 CANONICAL=A0A8V0YML2-1" }, "locus": { "chromosome": "2", "start_pos": 125975061, "end_pos": 125965443, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029798.1", "url": "https://www.ensembl.org/id/ENSGALT00010029798.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017350.1", "url": "https://www.ensembl.org/id/ENSGALP00010017350.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-1538133", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1538133", "resource": "Reactome", "description": "G0 and Early G1" }, { "id": "R-GGA-187577", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-187577", "resource": "Reactome", "description": "SCF(Skp2)-mediated degradation of p27/p21" }, { "id": "R-GGA-2559586", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2559586", "resource": "Reactome", "description": "DNA Damage/Telomere Stress Induced Senescence" }, { "id": "R-GGA-6804116", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6804116", "resource": "Reactome", "description": "TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest" }, { "id": "R-GGA-69017", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-69017", "resource": "Reactome", "description": "CDK-mediated phosphorylation and removal of Cdc6" }, { "id": "R-GGA-69200", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-69200", "resource": "Reactome", "description": "Phosphorylation of proteins involved in G1/S transition by active Cyclin E:Cdk2 complexes" }, { "id": "R-GGA-69202", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-69202", "resource": "Reactome", "description": "Cyclin E associated events during G1/S transition" }, { "id": "R-GGA-69231", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-69231", "resource": "Reactome", "description": "Cyclin D associated events in G1" }, { "id": "R-GGA-69563", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-69563", "resource": "Reactome", "description": "p53-Dependent G1 DNA Damage Response" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZQ41-1", "protein_name": "Cyclin E2", "gene_name": "Ccne2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSRRSSRLQAKQQHARPNQPDSPQEAQIIQAKKRKTAQDVKKRTEEITKKHQYEIRNCWPPVLSGGISPCIIIETPHKEIGTSDFSRFTNYRFKNLFINPSPLPDLSWACSQEVWQNMLQKESRYVHDKHFEVLHSDLEPQMRSILLDWLLEVCEVYTLHRETFYLAQDFFDRFMLTQKDVNKNMLQLIGITSLFIASKLEEIYAPKLQEFAYVTDGACSEVDILKMELNILKALKWELCPVTVISWLNLFLQVDAVKDIPKVLLPQYSQETFIQIAQLLDLCILAIDSLEFQYRILAAAALCHFTSIEVVKKASGLEWDDISECVDWMVPFVSVVKSVSPVKLKTFKKIPMEDRHNIQTHTNYLALLNEVNYVNIFRKGGQLSPVCNGGIMTPPKSTEKPPVKF", "length": 405 }, "evidence": [ { "id": "A0A8V0YML2", "url": "https://omabrowser.org/oma/group/A0A8V0YML2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1RY56-1", "protein_name": "Cyclin E2", "gene_name": "CCNE2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSRRSSRLQAKQQPQSSQTDSPQEAQIIQTKKRKTTQDVKKRKEEKVTKKHQYEIRNCWPPVLSGGISPCIIIETPHKEIGTSDFSRFTNYRFKNLFINPSPLPDLSWGCSQDVWLNMLKKETRYVHDKHFEVLHSDLEPQMRSILLDWLLEVCEVYTLHRETFYLAQDFFDRFMLTQKDINKNMLQLIGITSLFIASKLEEIYAPKLQEFAYVTDGACSEEDILRMELIILKALKWELCPVTVISWLNLFLQVDALKDAPKVLLPQYSQEKFIQIAQLLDLCILAIDSLEFQYRILAAAALCHFTSIEVVKKASGLEWDNISECVDWMVPFVSVVKSTSPVKLKIFKKISMEDRHNIQTHTNYLAMLDEANYVNTFRKGGQLSPVCNGGIMTPPKSTEKPPAKH", "length": 405 }, "evidence": [ { "id": "A0A8V0YML2", "url": "https://omabrowser.org/oma/group/A0A8V0YML2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "O96020-1", "protein_name": "G1/S-specific cyclin-E2", "gene_name": "CCNE2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSRRSSRLQAKQQPQPSQTESPQEAQIIQAKKRKTTQDVKKRREEVTKKHQYEIRNCWPPVLSGGISPCIIIETPHKEIGTSDFSRFTNYRFKNLFINPSPLPDLSWGCSKEVWLNMLKKESRYVHDKHFEVLHSDLEPQMRSILLDWLLEVCEVYTLHRETFYLAQDFFDRFMLTQKDINKNMLQLIGITSLFIASKLEEIYAPKLQEFAYVTDGACSEEDILRMELIILKALKWELCPVTIISWLNLFLQVDALKDAPKVLLPQYSQETFIQIAQLLDLCILAIDSLEFQYRILTAAALCHFTSIEVVKKASGLEWDSISECVDWMVPFVNVVKSTSPVKLKTFKKIPMEDRHNIQTHTNYLAMLEEVNYINTFRKGGQLSPVCNGGIMTPPKSTEKPPGKH", "length": 404 }, "evidence": [ { "id": "A0A8V0YML2", "url": "https://omabrowser.org/oma/group/A0A8V0YML2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q5E9K7-1", "protein_name": "G1/S-specific cyclin-E2", "gene_name": "CCNE2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSRRSSRLQAKQQPQASQTDSPQEAQIIQAKKRKTAQDVKKRKEEVTKKHQYEIRNCWPPVLSGGISPCIIIETPHKEIGTSDFSRFTNYRFKNLFINPSPLPDLSWGCSQDVWLNMLKKETRYVHDKHFEVLHSELEPQMRSILLDWLLEVCEVYTLHRETFYLAQDFFDRFMLTQKDINKNMLQLIGITSLFIASKLEEIYAPKLQEFAYVTDGACSEEDILRMELAILKALKWELCPVTVISWLNLFLQVDALKDAPKVLLPQYSQEKFIQIAQLLDLCILAIDSLEFQYRILAAAALCHFTSIEVVKKASGLEWDNISECVDWMVPFVSVVKSTSPAKLKIFKKISMEDRHNIQTHTNYLAMLDEVNYVNTFRKEGQLSPVCNGGIMTPPKSTEKPPGKH", "length": 404 }, "evidence": [ { "id": "A0A8V0YML2", "url": "https://omabrowser.org/oma/group/A0A8V0YML2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q9Z238-1", "protein_name": "G1/S-specific cyclin-E2", "gene_name": "Ccne2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSRRSSRLQAKQHAQPNQPDSPQETQIIQAKKRKTAQDVKKRKEEITKKHQYEIRNCWPPVLSGGISPCIIIETPHKEIGTSDFSRFTNYRFKNLFINPSPLPDLSWACSQEVWQNMLQKENRYVHDKHFQVLHSDLEPQMRSILLDWLLEVCEVYTLHRETFYLAQDFFDRFMLTQKDVNKNMLQLIGITSLFIASKLEEIYAPKLQEFAYVTDGACSEVDILKMELNILKALKWELCPVTVISWLNLFLQVDAVKDVPKVLLPQYSQETFIQIAQLLDLCILAIDSLEFQYRILAAAALCHFTSIEVVKKASGLEWDDISECVDWMVPFVSVVKSVSPVKLKTFKKIPMEDRHNIQTHTNYLALLNEVNYVNIYRKGGQLSPVCNGGIMTPPKSTEKPPGKH", "length": 404 }, "evidence": [ { "id": "A0A8V0YML2", "url": "https://omabrowser.org/oma/group/A0A8V0YML2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YML2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YML2" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YML2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YML2" } ], "pmid": "" }, { "name": "microtubule organizing center", "id": "GO:0005815", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005815", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YML2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YML2" } ], "pmid": "" }, { "name": "cyclin E1-CDK2 complex", "id": "GO:0097134", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097134", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YML2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YML2" } ], "pmid": "" }, { "name": "cyclin E2-CDK2 complex", "id": "GO:0097135", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097135", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YML2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YML2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YML2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YML2" } ], "pmid": "" }, { "name": "G1/S transition of mitotic cell cycle", "id": "GO:0000082", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000082", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YML2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YML2" } ], "pmid": "" }, { "name": "positive regulation of G1/S transition of mitotic cell cycle", "id": "GO:1900087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1900087", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YML2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YML2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "cyclin-dependent protein serine/threonine kinase regulator activity", "id": "GO:0016538", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016538", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YML2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YML2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 189, "end_pos": 191, "annotation": "n_glycosylation_sequon" }, { "start_pos": 328, "end_pos": 330, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YML2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YML2" }, { "id": "SM01332", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM01332" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Cyclin C-terminal", "eco_id": "ECO_0000259", "start_pos": 249, "end_pos": 370, "start_aa": "Val", "end_aa": "Tyr", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0YML2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YML2" }, { "id": "SM00385", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00385" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Cyclin-like", "eco_id": "ECO_0000259", "start_pos": 155, "end_pos": 240, "start_aa": "Asp", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 189, "end_pos": 191 }, { "start_pos": 328, "end_pos": 330 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YPL8-1", "uniprot_ac": "A0A8V0YPL8", "uniprot_id": "A0A8V0YPL8_CHICK", "mass": { "chemical_mass": 80260.0, "monoisotopic_mass": 80260.0 }, "refseq": { "ac": "XP_416439", "name": "integrator complex subunit 13", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_416439" }, "gene_names": [ { "name": "INTS13", "type": "recommended", "evidence": [ { "id": "A0A8V0YPL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPL8" } ] }, { "name": "INTS13", "type": "synonym", "evidence": [ { "id": "XP_416439", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_416439" } ] } ], "protein_names": [ { "name": "Integrator complex subunit 13", "type": "synonym", "evidence": [ { "id": "A0A8V0YPL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPL8/entry#names_and_taxonomy" } ] }, { "name": "integrator complex subunit 13", "type": "synonym", "evidence": [ { "id": "XP_416439", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_416439" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Dec 16, 2011 this sequence version replaced XP_416439.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_416439", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_416439" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPL8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPL8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "INTS13", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPL8", "locus": { "chromosome": "1", "start_pos": 68045295, "end_pos": 68065772, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010014728", "url": "https://www.ensembl.org/id/ENSGALG00010014728" } ] } } ], "crossref": [ { "id": "A0A8V0YPL8", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YPL8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000014083", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000014083", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "418213", "url": "https://www.ncbi.nlm.nih.gov/gene/418213", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR019355", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019355", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:418213", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418213", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "NCTAMHR", "url": "https://omabrowser.org/oma/group/NCTAMHR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YPL8", "url": "https://www.orthodb.org/?gene=A0A8V0YPL8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1P1V8", "url": "https://www.orthodb.org/?gene=F1P1V8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12955", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12955", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12955:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12955:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10221", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10221", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-6807505", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6807505", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_416439", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_416439", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YPL8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPL8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YPL8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPL8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1P1V8", "url": "https://www.uniprot.org/uniprotkb/F1P1V8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1P1V8-1", "url": "https://www.uniprot.org/uniprotkb/F1P1V8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKIFSESHKTVFVVDHCPYMAESCRQHVEFDMLVKNRTQGIIPLAPISKSLWTCSVESSMEYCRIMYDIFPFKKLVNFIVSDSGARVLNSWTQEDQNLQELMAALAAVGPPNPRADPECCSILHGLVAAVEALCKITEYQHEARTMLMENAERVGNRGRIICITNAKSDSHVRMLEDYVQETIHEHNKLAANSDHLMQIQKCELVLIHTYPVGEDSLVSDRPKKELSPVLTSEVHSVRAGRHLATKLNVLVQQHFDLASTTITNIPMKEEQHANTSANYDVELLHHKEAHVDFLKSGDNHVGGNSREGAFKETVTLKWCTPRTNSVELHYCTGAYRISPVDVNSRPSSCLTNFLLNGRSVLLEQPRKSGSKVISHMLSSHGGEIFLHVLSSSRSILEDPPSISEGCGGRVTDYRITDFGEFMRENRLTPFLEPRYKIDGSLEIPLERAKDQLEKHTRYWPMIISQTTIFNMQAVVPLASVIVKEAMTDEDVLNCQKTIYNLVDMERKNDPLPISTVGTRGKGPKRDEQYRIMWNELETLVRAHIGNSDKHQRVLECLMACRSKPPEEEERKKRGRKREDKEDKSEKSGKDYEPDKPWQESERLKGLLDREKEELAEAEVIKDSPDSPEPPNKKPLITMDEMPVVEKAKGPMSLLSLWSNRINTANSRKHQEFIGRLNSVNNKAELYQHLKEENGMETTENGKTGRQ", "length": 706, "header": "tr|A0A8V0YPL8-1|A0A8V0YPL8_CHICK Isoform 1 of Integrator complex subunit 13 OS=Gallus gallus OX=9031 GN=INTS13 PE=1 SV=1 CANONICAL=A0A8V0YPL8-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YPL8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPL8/entry#A0A8V0YPL8-1", "sequence": { "sequence": "MKIFSESHKTVFVVDHCPYMAESCRQHVEFDMLVKNRTQGIIPLAPISKSLWTCSVESSMEYCRIMYDIFPFKKLVNFIVSDSGARVLNSWTQEDQNLQELMAALAAVGPPNPRADPECCSILHGLVAAVEALCKITEYQHEARTMLMENAERVGNRGRIICITNAKSDSHVRMLEDYVQETIHEHNKLAANSDHLMQIQKCELVLIHTYPVGEDSLVSDRPKKELSPVLTSEVHSVRAGRHLATKLNVLVQQHFDLASTTITNIPMKEEQHANTSANYDVELLHHKEAHVDFLKSGDNHVGGNSREGAFKETVTLKWCTPRTNSVELHYCTGAYRISPVDVNSRPSSCLTNFLLNGRSVLLEQPRKSGSKVISHMLSSHGGEIFLHVLSSSRSILEDPPSISEGCGGRVTDYRITDFGEFMRENRLTPFLEPRYKIDGSLEIPLERAKDQLEKHTRYWPMIISQTTIFNMQAVVPLASVIVKEAMTDEDVLNCQKTIYNLVDMERKNDPLPISTVGTRGKGPKRDEQYRIMWNELETLVRAHIGNSDKHQRVLECLMACRSKPPEEEERKKRGRKREDKEDKSEKSGKDYEPDKPWQESERLKGLLDREKEELAEAEVIKDSPDSPEPPNKKPLITMDEMPVVEKAKGPMSLLSLWSNRINTANSRKHQEFIGRLNSVNNKAELYQHLKEENGMETTENGKTGRQ", "length": 706, "header": "tr|A0A8V0YPL8-1|A0A8V0YPL8_CHICK Isoform 1 of Integrator complex subunit 13 OS=Gallus gallus OX=9031 GN=INTS13 PE=1 SV=1 CANONICAL=A0A8V0YPL8-1" }, "locus": { "chromosome": "1", "start_pos": 68064685, "end_pos": 68045967, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010035391.1", "url": "https://www.ensembl.org/id/ENSGALT00010035391.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020597.1", "url": "https://www.ensembl.org/id/ENSGALP00010020597.1" } ] } }, { "isoform_ac": "F1P1V8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPL8/entry#F1P1V8-1", "sequence": { "sequence": "MCLSPTLFLSNSNICFRKKMKIFSESHKTVFVVDHCPYMAESCRQHVEFDMLVKNRTQGIIPLAPISKSLWTCSVESSMEYCRIMYDIFPFKKLVNFIVSDSGARVLNSWTQEDQNLQELMAALAAVGPPNPRADPECCSILHGLVAAVEALCKITEYQHEARTMLMENAERVGNRGRIICITNAKSDSHVRMLEDYVQETIHEHNKLAANSDHLMQIQKCELVLIHTYPVGEDSLVSDRPKKELSPVLTSEVHSVRAGRHLATKLNVLVQQHFDLASTTITNIPMKEEQHANTSANYDVELLHHKEAHVDFLKSGDNHVGGNSREGAFKETVTLKWCTPRTNSVELHYCTGAYRISPVDVNSRPSSCLTNFLLNGRSVLLEQPRKSGSKVISHMLSSHGGEIFLHVLSSSRSILEDPPSISEGCGGRVTDYRITDFGEFMRENRLTPFLEPRYKIDGSLEIPLERAKDQLEKHTRYWPMIISQTTIFNMQAVVPLASVIVKEAMTDEDVLNCQKTIYNLVDMERKNDPLPISTVGTRGKGPKRDEQYRIMWNELETLVRAHIGNSDKHQRVLECLMACRSKPPEEEERKKRGRKREDKEDKSEKSGKDYEPDKPWQESERLKGLLDREKEELAEAEVIKDSPDSPEPPNKKPLITMDEMPVVEKAKGPMSLLSLWSNRINTANSRKHQEFIGRLNSVNNKAELYQHLKEENGMETTENGKTGRQ", "length": 725, "header": "tr|F1P1V8-1|A0A8V0YPL8_CHICK Computationally mapped isoform of Integrator complex subunit 13 OS=Gallus gallus OX=9031 GN=INTS13 PE=1 SV=5 CANONICAL=A0A8V0YPL8-1" }, "locus": { "chromosome": "1", "start_pos": 68064742, "end_pos": 68045967, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010035379.1", "url": "https://www.ensembl.org/id/ENSGALT00010035379.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020590.1", "url": "https://www.ensembl.org/id/ENSGALP00010020590.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:418213", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418213", "resource": "KEGG Pathway" }, { "id": "R-GGA-6807505", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6807505", "resource": "Reactome", "description": "RNA polymerase II transcribes snRNA genes" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I5ZWB2-1", "protein_name": "Integrator complex subunit 13", "gene_name": "Ints13", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKIFSESHKTVFVVDHCPYMAESCRQHVEFDMLVKNRTQGIIPLAPISKSLWTCSVESSMEYCRIMYDIFPFKKLVNFIVSDSGAHVLNSWTQEDQNLQELMAALATVGPPNPRADPECCSILHGLVAAVETLCKITEYQHEARTLLMENAERVGNRGRIICITNAKSDSHVRMLEDCVQETIHEHNKLAANSDHLMQIQKCELVLIHTYPVGEDSLVSDRPKKELSPVLTSEVHSVRAGRHLATKLNVLVQQHFDLASTTITNIPMKEEQHANTSANYDVELLHHKDAHVDFLRSGDGHSGGSSREGPFKETVTLKWCTPRTNSIELHYCTGAYRISPVDVNSRPSSCLTNFLLNGRSVLLEQPRKSGSKVISHMLSSHGGEIFLHVLSSSRSILEDPPSISEGCGGRVTDYRITDFGEFMRENRLTPFLDPRYKMDASLEIPLERAKDQLEKHTRYWPMIISQTTIFNMQAVVPLAGVIVKESLTEEDVLNCQKTIYNLVDMERKNDPLPVSTVGTRGKGPKRDEQYRIMWNELETLVRAHISNSEKHQRVLECLMACRSKPPEEEERKKRGRKREDREDKSEQAGKEHGSEKPRPDADRLKGILERGKEELAEAEVIKDSPDSPEPPNKKPLVEMDETPHMEKSKGPVSLLSLWSNRINTANSRKHQEFAGRLNSVNNRAELYQHLKEENGEEVGLTGGPRTSIPFLKCPRSPVVNRMETTENGKASRQ", "length": 732 }, "evidence": [ { "id": "A0A8V0YPL8", "url": "https://omabrowser.org/oma/group/A0A8V0YPL8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3I0X3-1", "protein_name": "Integrator complex subunit 13 isoform X2", "gene_name": "Ints13", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MRIFSESHKTVFVVDHCPYMAESCRQHVEFDMLVKNRTPGIIPLAPISKSLWTCSVESSMEYCRIMYDIFPFKKLVNFIVSDSGAHVLNSWTQEDQNLQELMAALATVGPPNPRADPECCSILHGLVAAVETLCKITEYQHEARTLLMENAERVGNRGRIICITNAKSDSHVRMLEDCVQETIHEHNKLAANSDHLMQIQKCELVLIHTYPVGEDSLVSDRPKKELSPVLTSEVHSVRAGRHLATKLNVLVQQHFDLASTTITNIPMKEEQHANTSANYDVELLHHKDAHVDFLRSGDTHSGGSSREGPFKETVTLKWCTPRTNSIELHYCTGAYRISPVDVNSRPSSCLTNFLLNGRSVLLEQPRKSGSKVISHMLSSHGGEIFLHVLSSSRSILEDPPSISEGCGGRVTDYRITDFGEFMRENRLTPFLDPRYKMDASLEIPLERAKDQLEKHTRYWPMIISQTTIFNMQAVVPLASVIVKESLTEEDVLNCQKTIYNLVDMERKNDPLPISTVGTRGKGPKRDEQYRIMWNELETLVRAHVSNSEKHQRVLECLMACRSKPPEEEERKKRGRKREDREDKSEQAAKEHGPEKPRPDSDRLKGILERGKEELAEAEVIKDSPDSPEPPNKKPLVEMDETPHMEKSKGPMSLLSLWSNRINTANSRKHQEFAGRLNSVNNRAELYQHLKEENGMETTENGKASRQ", "length": 706 }, "evidence": [ { "id": "A0A8V0YPL8", "url": "https://omabrowser.org/oma/group/A0A8V0YPL8/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "I3LTH2-1", "protein_name": "Integrator complex subunit 13", "gene_name": "INTS13", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MKIFSESHKTVFVVDHCPYMAESCRQHVEFDMLVKNRTQGIIPLAPISKSLWTCSVESSMEYCRIMYDIFPFKKLVNFIVSDSGAHVLNSWTQEDQNLQELMAALAAVGPPNPRADPECCSILHGLVAAVETLCKITEYQHEARTLLMENAERVGNRGRIICITNAKSDSHVRMLEDCVQETIHEHNKLAANSDHLMQIQKCELVLIHTYPVGEDSLVSDRPKKELSPVLTSEVHSVRAGRHLATKLNILVQQHFDLASTTITNIPMKEEQHANTSANYDVELLHHKDAHVDFLKSGDNHLGSSSREGSFKETITLKWCTPRTNNIELHYCTGAYRISPVDVNSRPSSCLTNFLLNGRSVLLEQPRKSGSKVISHMLSSHGGEIFLHVLSSSRSILEDPPSISEGCGGRVTDYRITDFGEFMRENRLTPFLDPRYKIDGSLEIPLERAKDQLEKHTRYWPMIISQTTIFNMQAVVPLASVIVKESLTEEDVLNCQKTIYNLVDMERKNDPLPISTVGTRGKGPKRDEQYRIMWNELETLVRAHINNSEKHQRVLECLMACRSKPPEEEERKKRGRKREDKEDKSEKAVKDYEQEKSWQDSERLKGILERGKEELAEAEIIKDSPDSPEPPNKKPLVEMDETPPIEKSKGPVSLLSLWSNRINTANSRKHQEFAGRLNSVNNRAELYQHLKEENGMETTENGKASRQ", "length": 706 }, "evidence": [ { "id": "A0A8V0YPL8", "url": "https://omabrowser.org/oma/group/A0A8V0YPL8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q8QZV7-1", "protein_name": "Integrator complex subunit 13", "gene_name": "IntS13", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKIFSESHKTVFVVDHCPYMAESCRQHVEFDMLVKNRTQGIIPLAPISKSLWTCSVESSMEYCRIMYDIFPFKKLVNFIVSDSGAHVLNSWTQEDQNLQELMAALATVGPPNPRADPECCSILHGLVAAVETLCKITEYQHEARTLLMENAERVGNRGRIICITNAKSDSHVRMLEDCVQETIHEHNKLAANSDHLMQIQKCELVLIHTYPVGEDSLVSDRPKKELSPVLTSEVHSVRAGRHLATKLNVLVQQHFDLASTTITNIPMKEEQHANTSANYDVELLHHKDAHVDFLRSGDSHSGSSSREGPFKETVTLKWCTPRTNSIELHYCTGAYRISPVDVNSRPSSCLTNFLLNGRSVLLEQPRKSGSKVISHMLSSHGGEIFLHVLSSSRSILEDPPSISEGCGGRVTDYRITDFGEFMRENRLTPFLDPRYKIDASLEIPLERAKDQLEKHTRYWPMIISQTTIFNMQAVVPLAGVIVKESLTEEDVLNCQKTIYNLVDMERKNDPLPVSTVGTRGKGPKRDEQYRIMWNELETLVRAHISNSEKHQRVLECLMACRSKPPEEEERKKRGRKREDREDKSEQAGKEHGTEKARPDADRLKGILERGKEELAEAEVIKDSPDSPEPPNKKPLVETDETPHMEKSKGPVSLLSLWSNRINTANSRKHQEFAGRLNSVNNRAELYQHLKEENGEEVGLTGGPRTAIPFLKCPRSPVVNRMETTENGKASRQ", "length": 732 }, "evidence": [ { "id": "A0A8V0YPL8", "url": "https://omabrowser.org/oma/group/A0A8V0YPL8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9NVM9-1", "protein_name": "Integrator complex subunit 13", "gene_name": "INTS13", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKIFSESHKTVFVVDHCPYMAESCRQHVEFDMLVKNRTQGIIPLAPISKSLWTCSVESSMEYCRIMYDIFPFKKLVNFIVSDSGAHVLNSWTQEDQNLQELMAALAAVGPPNPRADPECCSILHGLVAAVETLCKITEYQHEARTLLMENAERVGNRGRIICITNAKSDSHVRMLEDCVQETIHEHNKLAANSDHLMQIQKCELVLIHTYPVGEDSLVSDRSKKELSPVLTSEVHSVRAGRHLATKLNILVQQHFDLASTTITNIPMKEEQHANTSANYDVELLHHKDAHVDFLKSGDSHLGGGSREGSFKETITLKWCTPRTNNIELHYCTGAYRISPVDVNSRPSSCLTNFLLNGRSVLLEQPRKSGSKVISHMLSSHGGEIFLHVLSSSRSILEDPPSISEGCGGRVTDYRITDFGEFMRENRLTPFLDPRYKIDGSLEVPLERAKDQLEKHTRYWPMIISQTTIFNMQAVVPLASVIVKESLTEEDVLNCQKTIYNLVDMERKNDPLPISTVGTRGKGPKRDEQYRIMWNELETLVRAHINNSEKHQRVLECLMACRSKPPEEEERKKRGRKREDKEDKSEKAVKDYEQEKSWQDSERLKGILERGKEELAEAEIIKDSPDSPEPPNKKPLVEMDETPQVEKSKGPVSLLSLWSNRINTANSRKHQEFAGRLNSVNNRAELYQHLKEENGMETTENGKASRQ", "length": 706 }, "evidence": [ { "id": "A0A8V0YPL8", "url": "https://omabrowser.org/oma/group/A0A8V0YPL8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VEX5-1", "protein_name": "Protein asunder", "gene_name": "Asun", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MFERNQKTIFVLDHTRYFSIASEEYISMDFLKGKPSADGGATGAAGNATGSGGSQFSKSLWTCACESSIEYCRVVWDLFPGKKHVRFIVSDTAAHIVNTWRPSTQNMAHVMNAMLIVGVPSRNVPTSSDYSVIHGLRAAIEALAEPTDEQLAAMADFGTDELPRIPNKGRVICITSARDNTSMKSLEDIFNTVLVQQNTLAAPPSKKGLVIDHCHLVILNIVPLGVESLVTNRSLLKISPLLDVEIHTVSAPDISYKLTHLILNHYDLASTTVTNIPMKEEQNANSSANYDVEILHSRRAHSITCGPDFSLPTSIKQGATYETVTLKWCTPRGCGSADLQPCLGQFLVTPVDVTSRPSSCLINFLLNGRSVLLEMPRKTGSKATSHMLSARGGEIFVHSLCITRSCMDEAPSITDGPGGRVSDYRTAELGQLIKMSRVVPLKVKDPSAPPLTRRLPRYFPLTTSSSILFHLQRHISWLPHFLHLLVKEDMDKQDEVRCQQHIHELYKSASRGDVLPFTHTNGARLKLSKAKDQYRLLYRELEQLIQLNATTMHHKNLLESLQSLRAAYGDAPLKSEPGASLLRTYTESPLSPERLEPISSVGASGSSSSNSLLKASKRRMSSCGQRSLLDIISSAERSQSNKRLDFSGRLCTPLGQVAKLYPDFGTKDKDTVTTGASITPNVKEESVRS", "length": 689 }, "evidence": [ { "id": "A0A8V0YPL8", "url": "https://omabrowser.org/oma/group/A0A8V0YPL8/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPL8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPL8" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPL8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPL8" } ], "pmid": "" }, { "name": "nuclear body", "id": "GO:0016604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016604", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPL8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPL8" } ], "pmid": "" }, { "name": "integrator complex", "id": "GO:0032039", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032039", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPL8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPL8" } ], "pmid": "" }, { "name": "INTAC complex", "id": "GO:0160232", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160232", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPL8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPL8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPL8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPL8" } ], "pmid": "" }, { "name": "regulation of transcription elongation by RNA polymerase II", "id": "GO:0034243", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034243", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPL8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPL8" } ], "pmid": "" }, { "name": "regulation of mitotic cell cycle", "id": "GO:0007346", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007346", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPL8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPL8" } ], "pmid": "" }, { "name": "snRNA processing", "id": "GO:0016180", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016180", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPL8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPL8" } ], "pmid": "" }, { "name": "centrosome localization", "id": "GO:0051642", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051642", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPL8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPL8" } ], "pmid": "" }, { "name": "RNA polymerase II transcription initiation surveillance", "id": "GO:0160240", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160240", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPL8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPL8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "DNA-binding transcription factor binding", "id": "GO:0140297", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140297", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPL8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPL8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 274, "end_pos": 276, "annotation": "n_glycosylation_sequon" }, { "start_pos": 36, "end_pos": 38, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 274, "end_pos": 276 }, { "start_pos": 36, "end_pos": 38 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": 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"count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { 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"https://bgee.org/?page=gene&gene_id=ENSGALG00000007493", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "422302", "url": "https://www.ncbi.nlm.nih.gov/gene/422302", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002225", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002225", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036291", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036291", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050177", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050177", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:422302", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422302", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "STAHWFD", "url": "https://omabrowser.org/oma/group/STAHWFD/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YH80", "url": "https://www.orthodb.org/?gene=A0A8V0YH80", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YP23", "url": "https://www.orthodb.org/?gene=A0A8V0YP23", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1C279", "url": "https://www.orthodb.org/?gene=E1C279", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR43245", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43245", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR43245:SF51", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43245:SF51", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01073", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01073", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-6807047", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6807047", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-6807062", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6807062", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "33447", "url": "https://www.rhea-db.org/rhea/33447", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "33455", "url": "https://www.rhea-db.org/rhea/33455", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "34771", "url": "https://www.rhea-db.org/rhea/34771", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "34775", "url": "https://www.rhea-db.org/rhea/34775", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "46828", "url": "https://www.rhea-db.org/rhea/46828", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "46848", "url": "https://www.rhea-db.org/rhea/46848", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "47160", "url": "https://www.rhea-db.org/rhea/47160", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "47164", "url": "https://www.rhea-db.org/rhea/47164", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "47168", "url": "https://www.rhea-db.org/rhea/47168", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "47172", "url": "https://www.rhea-db.org/rhea/47172", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YH80", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH80", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YH80-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH80-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YP23", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP23", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YP23-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP23-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C279", "url": "https://www.uniprot.org/uniprotkb/E1C279", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C279-1", "url": "https://www.uniprot.org/uniprotkb/E1C279-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MATHFRSTGKKCVVIGGSGFLGQHMVEKLLDKGYSVNVFDIQKRFDHDRVQFFLGDLCNKEALLPALQDVSVAFHCASPAPSSDNKELFYKVNFMGTKAVIEACKEAGVQKLVLTSSASVVFEGTDIKNGTEDLPYAKKPIDYYTETKILQEKEVLSANDPDNNFFTTAIRPHGIFGPRDPQLVPILIQAAKSGKMKFIIGDGKNLVDFTYVENVVHGHILAAEHLRKDSPVCGKAFHITNDEPIPFWAFMSRILTGLNYDAPKYYIPYWLAYYLALFLSLVLWLLSPLIIIKPTFTPMRVALAGTFHYYSCERAKRDMGYKPVVSLDGFYFYLIVLIILTSLHEH", "length": 346, "header": "tr|A0A8V0YP23-1|A0A8V0YP23_CHICK Isoform 1 of Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating OS=Gallus gallus OX=9031 GN=NSDHL PE=1 SV=1 CANONICAL=A0A8V0YP23-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YH80-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP23/entry#A0A8V0YH80-1", "sequence": { "sequence": "MVEKLLDKGYSVNVFDIQKRFDHDRVQFFLGDLCNKEALLPALQDVSVAFHCASPAPSSDNKELFYKVNFMGTKAVIEACKEAGVQKLVLTSSASVVFEGTDIKNGTEDLPYAKKPIDYYTETKILQEKEVLSANDPDNNFFTTAIRPHGIFGPRDPQLVPILIQAAKSGKMKFIIGDGKNLVDFTYVENVVHGHILAAEHLRKDSPVCGKAFHITNDEPIPFWAFMSRILTGLNYDAPKYYIPYWLAYYLALFLSLVLWLLSPLIIIKPTFTPMRVALAGTFHYYSCERAKRDMGYKPVVSLDEAIDRTLQSYPHLRRVKA", "length": 322, "header": "tr|A0A8V0YH80-1|A0A8V0YP23_CHICK Computationally mapped isoform of Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating OS=Gallus gallus OX=9031 GN=NSDHL PE=1 SV=1 CANONICAL=A0A8V0YP23-1" }, "locus": { "chromosome": "4", "start_pos": 11238228, "end_pos": 11232088, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030837.1", "url": "https://www.ensembl.org/id/ENSGALT00010030837.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017893.1", "url": "https://www.ensembl.org/id/ENSGALP00010017893.1" } ] } }, { "isoform_ac": "A0A8V0YP23-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP23/entry#A0A8V0YP23-1", "sequence": { "sequence": "MATHFRSTGKKCVVIGGSGFLGQHMVEKLLDKGYSVNVFDIQKRFDHDRVQFFLGDLCNKEALLPALQDVSVAFHCASPAPSSDNKELFYKVNFMGTKAVIEACKEAGVQKLVLTSSASVVFEGTDIKNGTEDLPYAKKPIDYYTETKILQEKEVLSANDPDNNFFTTAIRPHGIFGPRDPQLVPILIQAAKSGKMKFIIGDGKNLVDFTYVENVVHGHILAAEHLRKDSPVCGKAFHITNDEPIPFWAFMSRILTGLNYDAPKYYIPYWLAYYLALFLSLVLWLLSPLIIIKPTFTPMRVALAGTFHYYSCERAKRDMGYKPVVSLDGFYFYLIVLIILTSLHEH", "length": 346, "header": "tr|A0A8V0YP23-1|A0A8V0YP23_CHICK Isoform 1 of Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating OS=Gallus gallus OX=9031 GN=NSDHL PE=1 SV=1 CANONICAL=A0A8V0YP23-1" }, "locus": { "chromosome": "4", "start_pos": 11240367, "end_pos": 11232019, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030834.1", "url": "https://www.ensembl.org/id/ENSGALT00010030834.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017892.1", "url": "https://www.ensembl.org/id/ENSGALP00010017892.1" } ] } }, { "isoform_ac": "E1C279-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP23/entry#E1C279-1", "sequence": { "sequence": "MATHFRSTGKKCVVIGGSGFLGQHMVEKLLDKGYSVNVFDIQKRFDHDRVQFFLGDLCNKEALLPALQDVSVAFHCASPAPSSDNKELFYKVNFMGTKAVIEACKEAGVQKLVLTSSASVVFEGTDIKNGTEDLPYAKKPIDYYTETKILQEKEVLSANDPDNNFFTTAIRPHGIFGPRDPQLVPILIQAAKSGKMKFIIGDGKNLVDFTYVENVVHGHILAAEHLRKDSPVCGKAFHITNDEPIPFWAFMSRILTGLNYDAPKYYIPYWLAYYLALFLSLVLWLLSPLIIIKPTFTPMRVALAGTFHYYSCERAKRDMGYKPVVSLDEAIDRTLQSYPHLRRVKA", "length": 346, "header": "tr|E1C279-1|A0A8V0YP23_CHICK Computationally mapped isoform of Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating OS=Gallus gallus OX=9031 GN=NSDHL PE=1 SV=1 CANONICAL=A0A8V0YP23-1" }, "locus": { "chromosome": "4", "start_pos": 11240367, "end_pos": 11232088, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030829.1", "url": "https://www.ensembl.org/id/ENSGALT00010030829.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017888.1", "url": "https://www.ensembl.org/id/ENSGALP00010017888.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "gga:422302", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422302", "resource": "KEGG Pathway" }, { "id": "R-GGA-6807047", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6807047", "resource": "Reactome", "description": "Cholesterol biosynthesis via desmosterol (Bloch pathway)" }, { "id": "R-GGA-6807062", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6807062", "resource": "Reactome", "description": "Zymostenol biosynthesis via lathosterol (Kandutsch-Russell pathway)" } ], "orthologs": [ { "uniprot_canonical_ac": "F1S2D0-1", "protein_name": "Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating", "gene_name": "NSDHL", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEQAAGEPIKDQVTQTHLTEDIPKDRKCTVIGGSGFLGQHMVEQLLERGYAVNVFDKRQGFDNPRVQFFLGDLCNQQDLYPALKGVSTVFHCASPAPSSNNKELFYRVNYIGTKNVIETCREAGVQKLILTSSASVIFEGVDIKNGTEDLPYAMKPIDYYTETKILQEKTVLGANDPDKNFLTTAIRPHGIFGPRDPQLVPILIEAARKGKMKFVIGNGKNLVDFTFVENVVHGHILAAERLSRDTGLGGKAFHITNDEPVPFWTFLSRILTGLNYEAPKYHIPYWVAYYLALLVSLFVMVISPVIQLQPTFTPMRVALAGTFHYYSCEKAKKLLGYQPLVTMDDAVERTVQSFHHLRKAQ", "length": 361 }, "evidence": [ { "id": "A0A8V0YP23", "url": "https://omabrowser.org/oma/group/A0A8V0YP23/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P53199-1", "protein_name": "Sterol-4-alpha-carboxylate 3-dehydrogenase ERG26, decarboxylating", "gene_name": "ERG26", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSKIDSVLIIGGSGFLGLHLIQQFFDINPKPDIHIFDVRDLPEKLSKQFTFNVDDIKFHKGDLTSPDDMENAINESKANVVVHCASPMHGQNPDIYDIVNVKGTRNVIDMCKKCGVNILVYTSSAGVIFNGQDVHNADETWPIPEVPMDAYNETKAIAEDMVLKANDPSSDFYTVALRPAGIFGPGDRQLVPGLRQVAKLGQSKFQIGDNNNLFDWTYAGNVADAHVLAAQKLLDPKTRTAVSGETFFITNDTPTYFWALARTVWKADGHIDKHVIVLKRPVAICAGYLSEWVSKMLGKEPGLTPFRVKIVCAYRYHNIAKAKKLLGYTPRVGIEEGINKTLAWMDEGL", "length": 349 }, "evidence": [ { "id": "A0A8V0YP23", "url": "https://omabrowser.org/oma/group/A0A8V0YP23/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q15738-1", "protein_name": "Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating", "gene_name": "NSDHL", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEPAVSEPMRDQVARTHLTEDTPKVNADIEKVNQNQAKRCTVIGGSGFLGQHMVEQLLARGYAVNVFDIQQGFDNPQVRFFLGDLCSRQDLYPALKGVNTVFHCASPPPSSNNKELFYRVNYIGTKNVIETCKEAGVQKLILTSSASVIFEGVDIKNGTEDLPYAMKPIDYYTETKILQERAVLGANDPEKNFLTTAIRPHGIFGPRDPQLVPILIEAARNGKMKFVIGNGKNLVDFTFVENVVHGHILAAEQLSRDSTLGGKAFHITNDEPIPFWTFLSRILTGLNYEAPKYHIPYWVAYYLALLLSLLVMVISPVIQLQPTFTPMRVALAGTFHYYSCERAKKAMGYQPLVTMDDAMERTVQSFRHLRRVK", "length": 373 }, "evidence": [ { "id": "A0A8V0YP23", "url": "https://omabrowser.org/oma/group/A0A8V0YP23/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q3ZBE9-1", "protein_name": "Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating", "gene_name": "NSDHL", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MEQAAGEPTRTCLTEDIPKAKRCTVIGGCGFLGQHMVEQLLARGYAVNVFDIRQGFDNPRVQFFLGDLCSQQDLYPALKGVSTVFHCASPPPFNNNKELFYRVNYIGTKNVIETCKEAGVQKLILTSSASVIFEGVDIKNGTEDLPYATKPIDYYTETKILQERAVLGAHDPEKNFLTTAIRPHGIFGPRDPQLVPILIEAAKKGKMKFMIGNGKNLVDFTFVENVVHGHILAAEHLSQDTALGGKAFHITNDEPIPFWTFLSRILTGLNYEAPKYHIPYWLAYYLALLVSLLVMVISPVIQLQPTFTPMRVALAGTFHYYSCEKAKKLMGYRPLVTMDDAVDKTVRSFHHLRKVM", "length": 356 }, "evidence": [ { "id": "A0A8V0YP23", "url": "https://omabrowser.org/oma/group/A0A8V0YP23/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q5PPL3-1", "protein_name": "Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating", "gene_name": "Nsdhl", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEQAVRSESKKGQVTGTDLINEVSKAKKCTVIGGSGFLGQHMVEQLLSRGYAVNVFDVRQGFDNPRVQFFIGDLCNQQDLYPALKGVSTVFHCASPPSNSNNKELFYRVNSTGTKTVIETCKEAGVQKLILTSSASVVFEGVDIKNGTEDLPYAMKPIDYYTETKILQERAVLDANDPKKNFLTAAIRPHGIFGPRDPQLVPVLIDAARKGKMKFMIGNGKNLVDFTFVENVVHGHILAAEHLSRDAGLGGKAFHITNDEPIPFWTFLSRILTGLNYEAPKYHIPYRVAYYLAFLLSLLVMVLSPLIQIQTTFTPFRVALAGTFHYYSCEKAKKLIGYRPLVTMDDAVERTVQSFHHLRKDK", "length": 362 }, "evidence": [ { "id": "A0A8V0YP23", "url": "https://omabrowser.org/oma/group/A0A8V0YP23/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9FX01-1", "protein_name": "3beta-hydroxysteroid-dehydrogenase/decarboxylase isoform 1", "gene_name": "D1", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MVMEVTETERWCVVTGGRGFAARHLVEMLVRYQMFHVRIADLAPAIVLNPHEETGILGEAIRSGRVQYVSADLRNKTQVVKGFQGAEVVFHMAAPDSSINNHQLQYSVNVQGTTNVIDACIEVGVKRLIYTSSPSVVFDGVHGTLNADESLPYPPKHNDSYSATKAEGEALILKANGRSGLLTCCIRPSSIFGPGDKLMVPSLVTAARAGKSKFIIGDGSNFYDFTYVENVVHAHVCAERALASGGEVCAKAAGQAYFITNMEPIKFWEFMSQLLEGLGYERPSIKIPASLMMPIAYLVELAYKLLGPYGMKVPVLTPSRVRLLSCNRTFDSSKAKDRLGYSPVVPLQEGIKRTIDSFSHLKAQNQPKTEVTETIQWKKQTLIAIVILITLYHNFVATTGSSSVIITAVSKVLLVSSIFMFINGILPEKMKVFGSKKID", "length": 439 }, "evidence": [ { "id": "A0A8V0YP23", "url": "https://omabrowser.org/oma/group/A0A8V0YP23/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9R1J0-1", "protein_name": "Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating", "gene_name": "Nsdhl", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEQAVHGESKRGQVTGTHLTNDISKAKKCTVIGGSGFLGQHMVEQLLERGYTVNVFDIHQGFDNPRVQFFIGDLCNQQDLYPALKGVSTVFHCASPPPYSNNKELFYRVNFIGTKTVIETCREAGVQKLILTSSASVVFEGVDIKNGTEDLPYAMKPIDYYTETKILQERAVLDANDPKKNFLTAAIRPHGIFGPRDPQLVPILIDAARKGKMKFMIGNGENLVDFTFVENVVHGHILAAEHLSQDAALGGKAFHITNDEPIPFWTFLSRILTGLNYEAPKYHIPYWMAYYLAFLLSLLVMVVSPLIQIQPTFTPIRVALAGTFHYYSCEKAKKLFGYRPLVTMDEAVERTVQSFHHLRKDK", "length": 362 }, "evidence": [ { "id": "A0A8V0YP23", "url": "https://omabrowser.org/oma/group/A0A8V0YP23/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "lipid droplet", "id": "GO:0005811", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005811", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YP23", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP23" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YP23", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP23" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YP23", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP23" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "cholesterol biosynthetic process", "id": "GO:0006695", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006695", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YP23", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP23" } ], "pmid": "" }, { "name": "cholesterol metabolic process", "id": "GO:0008203", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008203", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YP23", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP23" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "3-beta-hydroxysteroid dehydrogenase [NAD(P)+]/C4-decarboxylase activity", "id": "GO:0000252", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000252", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YP23", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP23" } ], "pmid": "" }, { "name": "oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor", "id": "GO:0016616", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016616", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YP23", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP23" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 129, "end_pos": 131, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "33447", "name": "", "equation": "4beta-methylzymosterol-4alpha-carboxylate + NADP(+) = 3-dehydro-4-methylzymosterol + CO2 + NADPH", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YP23-1" ], "evidence": [ { "id": "33447", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/33447" } ] }, { "id": "33455", "name": "", "equation": "4alpha-carboxyzymosterol + NADP(+) = zymosterone + CO2 + NADPH", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YP23-1" ], "evidence": [ { "id": "33455", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/33455" } ] }, { "id": "34771", "name": "", "equation": "a 3beta-hydroxysteroid-4alpha-carboxylate + NADP(+) = a 3-oxosteroid + CO2 + NADPH", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YP23-1" ], "evidence": [ { "id": "34771", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/34771" } ] }, { "id": "34775", "name": "", "equation": "a 3beta-hydroxysteroid-4alpha-carboxylate + NAD(+) = a 3-oxosteroid + CO2 + NADH", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YP23-1" ], "evidence": [ { "id": "34775", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/34775" } ] }, { "id": "46828", "name": "", "equation": "4alpha-carboxy-4beta-methyl-5alpha-cholest-8-en-3beta-ol + NADP(+) = 4alpha-methyl-5alpha-cholest-8-en-3-one + CO2 + NADPH", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YP23-1" ], "evidence": [ { "id": "46828", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/46828" } ] }, { "id": "46848", "name": "", "equation": "4alpha-carboxy-5alpha-cholest-8-ene-3beta-ol + NADP(+) = 5alpha-cholest-8-en-3-one + CO2 + NADPH", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YP23-1" ], "evidence": [ { "id": "46848", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/46848" } ] }, { "id": "47160", "name": "", "equation": "4beta-methylzymosterol-4alpha-carboxylate + NAD(+) = 3-dehydro-4-methylzymosterol + CO2 + NADH", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YP23-1" ], "evidence": [ { "id": "47160", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/47160" } ] }, { "id": "47164", "name": "", "equation": "4alpha-carboxyzymosterol + NAD(+) = zymosterone + CO2 + NADH", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YP23-1" ], "evidence": [ { "id": "47164", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/47164" } ] }, { "id": "47168", "name": "", "equation": "4alpha-carboxy-4beta-methyl-5alpha-cholest-8-en-3beta-ol + NAD(+) = 4alpha-methyl-5alpha-cholest-8-en-3-one + CO2 + NADH", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YP23-1" ], "evidence": [ { "id": "47168", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/47168" } ] }, { "id": "47172", "name": "", "equation": "4alpha-carboxy-5alpha-cholest-8-ene-3beta-ol + NAD(+) = 5alpha-cholest-8-en-3-one + CO2 + NADH", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YP23-1" ], "evidence": [ { "id": "47172", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/47172" } ] }, { "id": "R-GGA-194642", "name": "4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form 4-methylcholesta-8(9),24-dien-3-one", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, endoplasmic reticulum membrane", "input_participant_list": [ "R-ALL-194735" ], "output_participant_list": [ "R-ALL-194667" ], "enzyme_list": [ "A0A8V0YP23-1" ], "evidence": [ { "id": "R-GGA-194642", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-194642" } ] }, { "id": "R-GGA-194718", "name": "4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form cholesta-8(9),24-dien-3-one (zymosterone)", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, endoplasmic reticulum membrane", "input_participant_list": [ "R-ALL-194657" ], "output_participant_list": [ "R-ALL-194661" ], "enzyme_list": [ "A0A8V0YP23-1" ], "evidence": [ { "id": "R-GGA-194718", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-194718" } ] }, { "id": "R-GGA-9945787", "name": "NSDHL decarboxylates 4a-carboxy-5a-cholest-8-ene-3b-ol to 5a-cholest-8-en-3-one", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, endoplasmic reticulum membrane", "input_participant_list": [ "R-ALL-9945792" ], "output_participant_list": [], "enzyme_list": [ "A0A8V0YP23-1" ], "evidence": [ { "id": "R-GGA-9945787", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9945787" } ] }, { "id": "R-GGA-9945822", "name": "NSDHL decarboxylates 4a-carboxy-4b-methyl-5a-cholest-8-en-3b-ol to 4a-methyl-5a-cholest-8-en-3b-ol", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. 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"id": "ZINC000030729904", "database": "ZINC", "url": "" }, { "id": "50593", "database": "ChEBI", "url": "" }, { "id": "ZINC000030729909", "database": "ZINC", "url": "" } ] }, { "participant_id": "R-ALL-194735", "participant_name": "4C4MZYMOL [endoplasmic reticulum membrane]", "crossref": [ { "id": "64925", "database": "ChEBI", "url": "" }, { "id": "ZINC000030729894", "database": "ZINC", "url": "" } ] }, { "participant_id": "R-ALL-9945792", "participant_name": "4a-carboxy-5a-cholest-8-en-3b-ol [endoplasmic reticulum membrane]", "crossref": [ { "id": "87055", "database": "ChEBI", "url": "" }, { "id": "ZINC000040165479", "database": "ZINC", "url": "" } ] }, { "participant_id": "R-ALL-9945802", "participant_name": "4a-me-5a-cholest-8-en-3-one [endoplasmic reticulum membrane]", "crossref": [ { "id": "ZINC000059789269", "database": "ZINC", "url": "" }, { "id": "87050", "database": "ChEBI", "url": "" }, { "id": "HMDB0062393", "database": "HMDB Metabolite", "url": "" } ] }, { "participant_id": 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"OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14826", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14826", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14826:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14826:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF12240", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12240", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-2028269", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2028269", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9762292", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9762292", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_046796460", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046796460", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YFQ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFQ6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YFQ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFQ6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLN9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLN9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLN9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLN9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLP4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLP4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLP4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLP4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YM36", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM36", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YM36-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM36-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YNW6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNW6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YNW6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNW6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YTW6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTW6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YTW6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTW6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C5Z2", "url": "https://www.uniprot.org/uniprotkb/E1C5Z2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C5Z2-1", "url": "https://www.uniprot.org/uniprotkb/E1C5Z2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRVCQLFWKRGEYQVICPTEEETEAISEWKFWTCGRKAVSPHVPEPLLLTKEVKVKDVGQGQLLHSTQKAPQFEMRNSEEQAATTVLQRLLQEQLRYGNPNDNRNLLALHQQATGNAPPFNSTGNPASQNEGLSSQDHQLVTHAARQEPQGQEIQVDNSIMEKQLSPRLQNSEDLPTYEEAKVQSQYFRGQPHASVGAAFYVTGVTNQKMRTEGRPTVQRVSPGKVHQDEGLKDLKQGHVRSLSERLMQLSLATSGVKAHAPVTSAPLSPLSPLSPQQSSDPYKNSGSSEFYKNSVQPPSQPSMKGMEQRGPPPEYPYKNVSTPSMNCKPQDSGHFYSDHRVSQQGRSDGPMMRYQHPPEYGSVRQNPDVQLQLQQRPPHHHSPTSSLTSLGSLTLLQSPPPSRLSPSQHQQPLTPSQGDPGILPRTQQPFLSNQVHQGDLYRLCQPFLGPQQQQGDSYSVMSRAQQIPSPYQQMQVDPFAIVSRAQQMVEILSEENRSLRQELDGCYEKVARLQKLETEIQQVSEAYKNLEKSSSKRDALEKAMRNKLEGEIRRLHDFNRDLRERMETANKQLAEKEFEGSEDNRKTISQLFAQNKETQREKEKLEIELAAARSTNEDQRRHIEIRDQALNNAQAKVVKLEEELKKKQVYVEKVEKMQQALVQLQAACEKREQLEHRLRTRLERELESLRMQQRQGTSQAANVSEYNATALMELLREKEERILALEADMTKWEQKYLEESVMRQFALDAAATVAAQRDTTVISHSPNPSYDTSLEARIQKEEEEILLANRRCLDMEGRIKTLHAQIIEKDAMIKVLQQRSRKEPGKTDQLSSMRPAKSLMSISNAGSGLLSHSSTLSSTPILEEKREDKSWKGSLGVLLGTEYRSESIPSTPSPVLPSTPLLSAHSKTGSRDCSTQTDRGNEQSKAAPSPAAPTPGRLPTASLPYSADKTDGPLFHSSTLERKAPVQTMGQDLPDGEMVEYLI", "length": 984, "header": "tr|A0A8V0YNW6-1|A0A8V0YNW6_CHICK Isoform 1 of Angiomotin OS=Gallus gallus OX=9031 GN=AMOT PE=3 SV=1 CANONICAL=A0A8V0YNW6-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YFQ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNW6/entry#A0A8V0YFQ6-1", "sequence": { "sequence": "MRNSEEQAATTVLQRLLQEQLRYGNPNDNRNLLALHQQATGNAPPFNSTGNPASQNEGLSSQDHQLVTHAARQEPQGQEIQVDNSIMEKQLSPRLQNSEDLPTYEEAKVQSQYFRGQPHASVGAAFYVTGVTNQKMRTEGRPTVQRVSPGKVHQDEGLKDLKQGHVRSLSERLMQLSLATSGVKAHAPVTSAPLSPLSPLSPQQSSDPYKNSGSSEFYKNSVQPPSQPSMKGMEQRGPPPEYPYKNVSTPSMNCKPQDSGHFYSDHRVSQQGRSDGPMMRYQHPPEYGSVRQNPDVQLQLQQRPPHHHSPTSSLTSLGSLTLLQSPPPSRLSPSQHQQPLTPSQGDPGILPRTQQPFLSNQVHQGDLYRLCQPFLGPQQQQGDSYSVMSRAQQIPSPYQQMQVDPFAIVSRAQQMVEILSEENRSLRQELDGCYEKVARLQKLETEIQQVSEAYKNLEKSSSKRDALEKAMRNKLEGEIRRLHDFNRDLRERMETANKQLAEKEFEGSEDNRKTISQLFAQNKETQREKEKLEIELAAARSTNEDQRRHIEIRDQALNNAQAKVVKLEEELKKKQVYVEKVEKMQQALVQLQAACEKREQLEHRLRTRLERELESLRMQQGTSQAANVSEYNATALMELLREKEERILALEADMTKWEQKYLEESVMRQFALDAAATVAAQRDTTVISHSPNPSYDTSLEARIQKEEEEILLANRRCLDMEGRIKTLHAQIIEKDAMIKVLQQRSRKEPGKTDQLSSMRPAKSLMSISNAGSGLLSHSSTLSSTPILEEKREDKSWKGSLGVLLGTEYRSESIPSTPSPVLPSTPLLSAHSKTGSRDCSTQTDRGNEQSKAAPSPAAPTPGRLPTASLPYSADKTDGPLFHSSTLERKAPVQTMGQDLPDGEMVEYLI", "length": 908, "header": "tr|A0A8V0YFQ6-1|A0A8V0YNW6_CHICK Computationally mapped isoform of Angiomotin OS=Gallus gallus OX=9031 GN=AMOT PE=3 SV=1 CANONICAL=A0A8V0YNW6-1" }, "locus": { "chromosome": "4", "start_pos": 12970891, "end_pos": 12937521, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033347.1", "url": "https://www.ensembl.org/id/ENSGALT00010033347.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019678.1", "url": "https://www.ensembl.org/id/ENSGALP00010019678.1" } ] } }, { "isoform_ac": "A0A8V0YLN9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNW6/entry#A0A8V0YLN9-1", "sequence": { "sequence": "MRAPRVASALPRPAPPRSAGSGQGQLLHSTQKAPQFEMRNSEEQAATTVLQRLLQEQLRYGNPNDNRNLLALHQQATGNAPPFNSTGNPASQNEGLSSQDHQLVTHAARQEPQGQEIQVDNSIMEKQLSPRLQNSEDLPTYEEAKVQSQYFRGQPHASVGAAFYVTGVTNQKMRTEGRPTVQRVSPGKVHQDEGLKDLKQGHVRSLSERLMQLSLATSGVKAHAPVTSAPLSPLSPLSPQQSSDPYKNSGSSEFYKNSVQPPSQPSMKGMEQRGPPPEYPYKNVSTPSMNCKPQDSGHFYSDHRVSQQGRSDGPMMRYQHPPEYGSVRQNPDVQLQLQQRPPHHHSPTSSLTSLGSLTLLQSPPPSRLSPSQHQQPLTPSQGDPGILPRTQQPFLSNQVHQGDLYRLCQPFLGPQQQQGDSYSVMSRAQQIPSPYQQMQVDPFAIVSRAQQMVEILSEENRSLRQELDGCYEKVARLQKLETEIQQVSEAYKNLEKSSSKRDALEKAMRNKLEGEIRRLHDFNRDLRERMETANKQLAEKEFEGSEDNRKTISQLFAQNKETQREKEKLEIELAAARSTNEDQRRHIEIRDQALNNAQAKVVKLEEELKKKQVYVEKVEKMQQALVQLQAACEKREQLEHRLRTRLERELESLRMQQRQGTSQAANVSEYNATALMELLREKEERILALEADMTKWEQKYLEESVMRQFALDAAATVAAQRDTTVISHSPNPSYDTSLEARIQKEEEEILLANRRCLDMEGRIKTLHAQIIEKDAMIKVLQQRSRKEPGKTDQLSSMRPAKSLMSISNAGSGLLSHSSTLSSTPILEEKREDKSWKGSLGVLLGTEYRSESIPSTPSPVLPSTPLLSAHSKTGSRDCSTQTDRGNEQSKAAPSPAAPTPGRLPTASLPYSADKTDGPLFHSSTLERKAPVQTMGQDLPDGEMVEYLI", "length": 947, "header": "tr|A0A8V0YLN9-1|A0A8V0YNW6_CHICK Computationally mapped isoform of Angiomotin OS=Gallus gallus OX=9031 GN=AMOT PE=3 SV=1 CANONICAL=A0A8V0YNW6-1" }, "locus": { "chromosome": "4", "start_pos": 12970891, "end_pos": 12922564, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033323.1", "url": "https://www.ensembl.org/id/ENSGALT00010033323.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019667.1", "url": "https://www.ensembl.org/id/ENSGALP00010019667.1" } ] } }, { "isoform_ac": "A0A8V0YLP4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNW6/entry#A0A8V0YLP4-1", "sequence": { "sequence": "MRNSEEQAATTVLQRLLQEQLRYGNPNDNRNLLALHQQATGNAPPFNSTGNPASQNEGLSSQDHQLVTHAARQEPQGQEIQVDNSIMEKQLSPRLQNSEDLPTYEEAKVQSQYFRGQPHASVGAAFYVTGVTNQKMRTEGRPTVQRVSPGKVHQDEGLKDLKQGHVRSLSERLMQLSLATSGVKAHAPVTSAPLSPLSPLSPQQSSDPYKNSGSSEFYKNSVQPPSQPSMKGMEQRGPPPEYPYKNVSTPSMNCKPQDSGHFYSDHRVSQQGRSDGPMMRYQHPPEYGSVRQNPDVQLQLQQRPPHHHSPTSSLTSLGSLTLLQSPPPSRLSPSQHQQPLTPSQGDPGILPRTQQPFLSNQVHQGDLYRLCQPFLGPQQQQGDSYSVMSRAQQIPSPYQQMQVDPFAIVSRAQQMVEILSEENRSLRQELDGCYEKVARLQKLETEIQQVSEAYKNLEKSSSKRDALEKAMRNKLEGEIRRLHDFNRDLRERMETANKQLAEKEFEGSEDNRKTISQLFAQNKETQREKEKLEIELAAARSTNEDQRRHIEIRDQALNNAQAKVVKLEEELKKKQVYVEKVEKMQQALVQLQAACEKREQLEHRLRTRLERELESLRMQQAANVSEYNATALMELLREKEERILALEADMTKWEQKYLEESVMRQFALDAAATVAAQRDTTVISHSPNPSYDTSLEARIQKEEEEILLANRRCLDMEGRIKTLHAQIIEKDAMIKVLQQRSRKEPGKTDQLSSMRPAKSLMSISNAGSGLLSHSSTLSSTPILEEKREDKSWKGSLGVLLGTEYRSESIPSTPSPVLPSTPLLSAHSKTGSRDCSTQTDRGNEQSKAAPSPAAPTPGRLPTASLPYSADKTDGPLFHSSTLERKAPVQTMGQDLPDGEMVEYLI", "length": 904, "header": "tr|A0A8V0YLP4-1|A0A8V0YNW6_CHICK Computationally mapped isoform of Angiomotin OS=Gallus gallus OX=9031 GN=AMOT PE=3 SV=1 CANONICAL=A0A8V0YNW6-1" }, "locus": { "chromosome": "4", "start_pos": 12970891, "end_pos": 12937521, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033331.1", "url": "https://www.ensembl.org/id/ENSGALT00010033331.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019672.1", "url": "https://www.ensembl.org/id/ENSGALP00010019672.1" } ] } }, { "isoform_ac": "A0A8V0YM36-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNW6/entry#A0A8V0YM36-1", "sequence": { "sequence": "MRNSEEQAATTVLQRLLQEQLRYGNPNDNRNLLALHQQATGNAPPFNSTGNPASQNEGLSSQDHQLVTHAARQEPQGQEIQVDNSIMEKQLSPRLQNSEDLPTYEEAKVQSQYFRGQPHASVGAAFYVTGVTNQKMRTEGRPTVQRVSPGKVHQDEGLKDLKQGHVRSLSERLMQLSLATSGVKAHAPVTSAPLSPLSPLSPQQSSDPYKNSGSSEFYKNSVQPPSQPSMKGMEQRGPPPEYPYKNVSTPSMNCKPQDSGHFYSDHRVSQQGRSDGPMMRYQHPPEYGSVRQNPDVQLQLQQRPPHHHSPTSSLTSLGSLTLLQSPPPSRLSPSQHQQPLTPSQGDPGILPRTQQPFLSNQVHQGDLYRLCQPFLGPQQQQGDSYSVMSRAQQIPSPYQQMQVDPFAIVSRAQQMVEILSEENRSLRQELDGCYEKVARLQKLETEIQQVSEAYKNLEKSSSKRDALEKAMRNKLEGEIRRLHDFNRDLRERMETANKQLAEKEFEGSEDNRKTISQLFAQNKETQREKEKLEIELAAARSTNEDQRRHIEIRDQALNNAQAKVVKLEEELKKKQVYVEKVEKMQQALVQLQAACEKREQLEHRLRTRLERELESLRMQQRQGTSQAANVSEYNATALMELLREKEERILALEADMTKWEQKYLEESVMRQFALDAAATVAAQRDTTVISHSPNPSYDTSLEARIQKEEEEILLANRRCLDMEGRIKTLHAQIIEKDAMIKVLQQRSRKEPGKTDQLSSMRPAKSLMSISNAGSGLLSHSSTLSSTPILEEKREDKSWKGSLVGTEYRSESIPSTPSPVLPSTPLLSAHSKTGSRDCSTQTDRGNEQSKAAPSPAAPTPGRLPTASLPYSADKTDGPLFHSSTLERKAPVQTMGQDLPDGEMVEYLI", "length": 907, "header": "tr|A0A8V0YM36-1|A0A8V0YNW6_CHICK Computationally mapped isoform of Angiomotin OS=Gallus gallus OX=9031 GN=AMOT PE=3 SV=1 CANONICAL=A0A8V0YNW6-1" }, "locus": { "chromosome": "4", "start_pos": 12970891, "end_pos": 12937521, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033327.1", "url": "https://www.ensembl.org/id/ENSGALT00010033327.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019670.1", "url": "https://www.ensembl.org/id/ENSGALP00010019670.1" } ] } }, { "isoform_ac": "A0A8V0YNW6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNW6/entry#A0A8V0YNW6-1", "sequence": { "sequence": "MRVCQLFWKRGEYQVICPTEEETEAISEWKFWTCGRKAVSPHVPEPLLLTKEVKVKDVGQGQLLHSTQKAPQFEMRNSEEQAATTVLQRLLQEQLRYGNPNDNRNLLALHQQATGNAPPFNSTGNPASQNEGLSSQDHQLVTHAARQEPQGQEIQVDNSIMEKQLSPRLQNSEDLPTYEEAKVQSQYFRGQPHASVGAAFYVTGVTNQKMRTEGRPTVQRVSPGKVHQDEGLKDLKQGHVRSLSERLMQLSLATSGVKAHAPVTSAPLSPLSPLSPQQSSDPYKNSGSSEFYKNSVQPPSQPSMKGMEQRGPPPEYPYKNVSTPSMNCKPQDSGHFYSDHRVSQQGRSDGPMMRYQHPPEYGSVRQNPDVQLQLQQRPPHHHSPTSSLTSLGSLTLLQSPPPSRLSPSQHQQPLTPSQGDPGILPRTQQPFLSNQVHQGDLYRLCQPFLGPQQQQGDSYSVMSRAQQIPSPYQQMQVDPFAIVSRAQQMVEILSEENRSLRQELDGCYEKVARLQKLETEIQQVSEAYKNLEKSSSKRDALEKAMRNKLEGEIRRLHDFNRDLRERMETANKQLAEKEFEGSEDNRKTISQLFAQNKETQREKEKLEIELAAARSTNEDQRRHIEIRDQALNNAQAKVVKLEEELKKKQVYVEKVEKMQQALVQLQAACEKREQLEHRLRTRLERELESLRMQQRQGTSQAANVSEYNATALMELLREKEERILALEADMTKWEQKYLEESVMRQFALDAAATVAAQRDTTVISHSPNPSYDTSLEARIQKEEEEILLANRRCLDMEGRIKTLHAQIIEKDAMIKVLQQRSRKEPGKTDQLSSMRPAKSLMSISNAGSGLLSHSSTLSSTPILEEKREDKSWKGSLGVLLGTEYRSESIPSTPSPVLPSTPLLSAHSKTGSRDCSTQTDRGNEQSKAAPSPAAPTPGRLPTASLPYSADKTDGPLFHSSTLERKAPVQTMGQDLPDGEMVEYLI", "length": 984, "header": "tr|A0A8V0YNW6-1|A0A8V0YNW6_CHICK Isoform 1 of Angiomotin OS=Gallus gallus OX=9031 GN=AMOT PE=3 SV=1 CANONICAL=A0A8V0YNW6-1" }, "locus": { "chromosome": "4", "start_pos": 12970891, "end_pos": 12913201, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033342.1", "url": "https://www.ensembl.org/id/ENSGALT00010033342.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019676.1", "url": "https://www.ensembl.org/id/ENSGALP00010019676.1" } ] } }, { "isoform_ac": "A0A8V0YTW6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNW6/entry#A0A8V0YTW6-1", "sequence": { "sequence": "MRNSEEQAATTVLQRLLQEQLRYGNPNDNRNLLALHQQATGNAPPFNSTGNPASQNEGLSSQDHQLVTHAARQEPQGQEIQVDNSIMEKQLSPRLQNSEDLPTYEEAKVQSQYFRGQPHASVGAAFYVTGVTNQKMRTEGRPTVQRVSPGKVHQDEGLKDLKQGHVRSLSERLMQLSLATSGVKAHAPVTSAPLSPLSPLSPQQSSDPYKNSGSSEFYKNSVQPPSQPSMKGMEQRGPPPEYPYKNVSTPSMNCKPQDSGHFYSDHRVSQQGRSDGPMMRYQHPPEYGSVRQNPDVQLQLQQRPPHHHSPTSSLTSLGSLTLLQSPPPSRLSPSQHQQPLTPSQGDPGILPRTQQPFLSNQVHQGDLYRLCQPFLGPQQQQGDSYSVMSRAQQIPSPYQQMQVDPFAIVSRAQQMVEILSEENRSLRQELDGCYEKVARLQKLETEIQQVSEAYKNLEKSSSKRDALEKAMRNKLEGEIRRLHDFNRDLRERMETANKQLAEKEFEGSEDNRKTISQLFAQNKETQREKEKLEIELAAARSTNEDQRRHIEIRDQALNNAQAKVVKLEEELKKKQVYVEKVEKMQQALVQLQAACEKREQLEHRLRTRLERELESLRMQQRQGTSQAANVSEYNATALMELLREKEERILALEADMTKWEQKYLEESVMRQFALDAAATVAAQRDTTVISHSPNPSYDTSLEARIQKEEEEILLANRRCLDMEGRKRIKTLHAQIIEKDAMIKVLQQRSRKEPGKTDQLSSMRPAKSLMSISNAGSGLLSHSSTLSSTPILEEKREDKSWKGSLGVLLGTEYRSESIPSTPSPVLPSTPLLSAHSKTGSRDCSTQTDRGNEQSKAAPSPAAPTPGRLPTASLPYSADKTDGPLFHSSTLERKAPVQTMGQDLPDGEMVEYLI", "length": 912, "header": "tr|A0A8V0YTW6-1|A0A8V0YTW6_CHICK Computationally mapped isoform of Angiomotin OS=Gallus gallus OX=9031 GN=AMOT PE=3 SV=1 CANONICAL=A0A8V0YNW6-1" }, "locus": { "chromosome": "4", "start_pos": 12970891, "end_pos": 12937521, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033316.1", "url": "https://www.ensembl.org/id/ENSGALT00010033316.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019664.1", "url": "https://www.ensembl.org/id/ENSGALP00010019664.1" } ] } }, { "isoform_ac": "E1C5Z2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNW6/entry#E1C5Z2-1", "sequence": { "sequence": "MRNSEEQAATTVLQRLLQEQLRYGNPNDNRNLLALHQQATGNAPPFNSTGNPASQNEGLSSQDHQLVTHAARQEPQGQEIQVDNSIMEKQLSPRLQNSEDLPTYEEAKVQSQYFRGQPHASVGAAFYVTGVTNQKMRTEGRPTVQRVSPGKVHQDEGLKDLKQGHVRSLSERLMQLSLATSGVKAHAPVTSAPLSPLSPLSPQQSSDPYKNSGSSEFYKNSVQPPSQPSMKGMEQRGPPPEYPYKNVSTPSMNCKPQDSGHFYSDHRVSQQGRSDGPMMRYQHPPEYGSVRQNPDVQLQLQQRPPHHHSPTSSLTSLGSLTLLQSPPPSRLSPSQHQQPLTPSQGDPGILPRTQQPFLSNQVHQGDLYRLCQPFLGPQQQQGDSYSVMSRAQQIPSPYQQMQVDPFAIVSRAQQMVEILSEENRSLRQELDGCYEKVARLQKLETEIQQVSEAYKNLEKSSSKRDALEKAMRNKLEGEIRRLHDFNRDLRERMETANKQLAEKEFEGSEDNRKTISQLFAQNKETQREKEKLEIELAAARSTNEDQRRHIEIRDQALNNAQAKVVKLEEELKKKQVYVEKVEKMQQALVQLQAACEKREQLEHRLRTRLERELESLRMQQRQGTSQAANVSEYNATALMELLREKEERILALEADMTKWEQKYLEESVMRQFALDAAATVAAQRDTTVISHSPNPSYDTSLEARIQKEEEEILLANRRCLDMEGRIKTLHAQIIEKDAMIKVLQQRSRKEPGKTDQLSSMRPAKSLMSISNAGSGLLSHSSTLSSTPILEEKREDKSWKGSLGVLLGTEYRSESIPSTPSPVLPSTPLLSAHSKTGSRDCSTQTDRGNEQSKAAPSPAAPTPGRLPTASLPYSADKTDGPLFHSSTLERKAPVQTMGQDLPDGEMVEYLI", "length": 910, "header": "tr|E1C5Z2-1|A0A8V0YNW6_CHICK Computationally mapped isoform of Angiomotin OS=Gallus gallus OX=9031 GN=AMOT PE=3 SV=3 CANONICAL=A0A8V0YNW6-1" }, "locus": { "chromosome": "4", "start_pos": 12970891, "end_pos": 12937521, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033336.1", "url": "https://www.ensembl.org/id/ENSGALT00010033336.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019674.1", "url": "https://www.ensembl.org/id/ENSGALP00010019674.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 892, "start_aa": "Thr", "end_pos": 892, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr892", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 935, "start_aa": "Thr", "end_pos": 935, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr935", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:422336", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422336", "resource": "KEGG Pathway" }, { "id": "R-GGA-2028269", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2028269", "resource": "Reactome", "description": "Signaling by Hippo" }, { "id": "R-GGA-9762292", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9762292", "resource": "Reactome", "description": "Regulation of CDH11 function" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2JX94-1", "protein_name": "Angiomotin", "gene_name": "Amot", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRNSEDQPSGGTTVLQRLLQEQLRYGNPSENRSLLAIHQQATGNSSPFSTGSGNPVPQNDVLSSQDHHQQLVAHPARQEPQGQEIQSENGVMEKQVSPRMQNNEELPTYEEAKVQSQYFRGQQHASVGAAFYVTGVTNQKMRTEGRPSVQRLTPGKMHQDEGLRDLKQGHVRSLSERLMQMSLATSGVKAHPPVTSAPLSPPQPNDLYKNPTSSSEFYKAQGPPPSQHSLKSMEHRGPPPEYPFKGVPSQSVVCKSQEPGHFYSEHRLNQPGRTEGQLMRYQHPPEYGAARATQDIASLSFSARNSQPHSPTSSLTAGAASLPLLQSPPSTRLSSGQHGLVSNQGDHSAHLPRHQQHLLPNQSHQGDHYRHPQPSLTPAQQQPGEAYSAMPRAQQAAAYQPMPADPFAIVSRAQQMVEILSDENRNLRQELDGCYEKVARLQKVETEIQRVSEAYETLVKSSSKREALEKAMRNKLEGEIRRMHDFNRDLRDRLETANKQLAEKEYEGSEDTRKTISQLFAKHKENQREKEKLEAELATARSTNEDQRRHIEIRDQALSNAQAKVVKLEEELKKKQVYVDKVEKMQQALVQLQAACEKREQLEHRLRTRLERELESLRIQQRQGNSQPTNASEYNAAALMELLREKEERILALEADMTKWEQKYLEENVMRHFALDAAATVAAQRDTTVISHSPNTSYDTALEARIQKEEEEILMANKRCLDMEGRIKTLHAQIIEKDAMIKVLQQRSRKEPSKTEQLSSMRPAKSLMSISNAGSGLLVHSSTLTGVPIMEEKRDDKSWKGSLGILLGGDYRAEPVPSTPSPVPPSTPLLSAHSKTGSRDCSTQTERGSESTKTAAVTPISVPMAGPVAAAAPAAAINATAATNTATAATNTTIMVAAAPVAVAAAAAPAAATATPSPANAAALAAAAAAAVTPATPVSAATSVSAATSISQAAPVSPAAPVSPAAPVSPAAAGQIAVAASLTSATVSPTPAAATAAGAAAGAGAGAGAGAAAGAAVATVAAAATTTAIQVAPATSAPVPSPASIPAPATAQASAPTPTQASTPAPIEPPTAVPTPTPALVQAEGPASPGASSGPRRLSTPNLMCNPDKPDGPAFHSSTLERKTPIQILGQEPDAEMVEYLI", "length": 1142 }, "evidence": [ { "id": "A0A8V0YNW6", "url": "https://omabrowser.org/oma/group/A0A8V0YNW6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A3Q1M4X1-1", "protein_name": "Angiomotin", "gene_name": "AMOT", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MNFLLSALQVGTSDPGAVYYKVSIKGQGQPRCPISLSLHKAPPAIEMRNSDEQPSGGTTVLQRLLQEQLRYGNPNENRNLLAIHQQATGNGPPFPSGSGNPGPQNDVLSPQDHHQQLVAHAARQEPQGQEIQSENIIMEKQLSPRMQNNEELPTYEEAKVQSQYFRGQQHASVGAAFYVTGVTNQKMRTEGRPSVQRLNPGKMHQDEGLRDLKQGHVRSLSERLMQMSLATSGVKAHPPVTSAPLSPPQPNDLYKNPTSSSDFYKAQGPPPSQHSLKGMEHRGPPPEYPFKGMPPQSIVCKPQEPGHYYSEHRLNQPGRTEGQLMRYQHPPEYGAARPTQDISLPLSARNSQPHSPTSSLTSGGSLPLLQSPPSTRLSPAQHPLVPNQGDHSAHLPRPQQHFLPNQAHQGDHYRLPQPGLSQQQPQQPQPHHHHHHQQQQQPGEGYSAMPRAQQSSASYQPMPADPFAIVSRAQQMVEILSDENRNLRQELEGCYEKVARLQKVETEIQRVSEAYENLVKSSSKREALEKAMRNKLEGEIRRMHDFNRDLRERLETANKQLAEKEYEGSEDTRKTISQLFAKNKESQREKEKLEAELATARSTNEDQRRHIEIRDQALSNAQAKVVKLEEELKKKQVYVDKVEKMQQALVQLQAACEKREQLEHRLRTRLERELESLRIQQRQGNSQPTNVSEYNAAALMEILREKEERILALEADMTKWEQKYLEENVMRHFALDAAATVAAQRDTTVISHSPNTSYDTALEARIQKEEEEILMANKRCLDMEGRIKTLHAQIIEKDAMIKVLQQRSRKEPSKTEQLSSMRPAKSLMSISNAGSGLLSHSSTLTGTPIMEEKRDDKSWKGSLGILLAGDYRAESVPSTPSPVPPSTPLLSAHSKTGSRDCSTQTERGVESNKTNVVAPISVPAPVAAAAAAATITAAAATNTTTMVAAAPVAVAAATAPATAAATTPSPATAAATLAAAVSPAATAAPVPATASAVTATVVAPVAATAIQVAPAVPAPVPAPAPTPVPAPVAAQASAPAQTQAPTPAPAAAAPPAPTPAPALAQSEAPASPATGSGPRRLSTPSLSCNPDKPDGSVFHSNTLERKTPIQILGQEPDTEMVEYLI", "length": 1125 }, "evidence": [ { "id": "A0A8V0YNW6", "url": "https://omabrowser.org/oma/group/A0A8V0YNW6/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A8M2BL72-1", "protein_name": "Angiomotin isoform X1", "gene_name": "amot", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MFRKKASSSLRMRGISENNRRSVDRARSSSFHEVGRSRDLEMRAAASVSEDTSANNSGGSGHTVLQRLLQEQMRYGEGRNYLALQQQQQQGPVSGYPGPGSPADEHSMVPHIARQEPQGQELQVDSGMEKLSTRTAGGGGGSGGTGSLGGSCVSGQMQNPEDLPTYDQAKVQSQYFRGHQPQQPQPQMPPTVGAAFYVTGVTNSKVRPPEGRSTVQRMNGGKVHQDDGLKDLKQGHVRSLSERLMQLSLATSGVKAHAPVTSSPLSPQLPPPGLPGDYYKPTGPPHRGPPPDYPFKGMPSPPKQQQHHQPQHQEPGHFHPDHRGTSQPARTDIPHVRYQPPPEYGSFRSSKESSSHSQRSVHHHSPSSSVTSGGSLSRAQSSTLSSILAASHALPPMGHSGEPPFPIGARSSQGPGSHQGDPYGPGHPPHQRSHVFPHDHYGSAPRGLHMLQHQYHQQGPQQQQQQSPAQHYSHPLSMQGDPYAMLARAQQMVDMLSEENRLLKQELEVCGEKVSKLQKMETEIQMVSEAYENLAKSSTKREALEKTMRNKLEMEVRRVHDFNRDLRERMETANKQLAAKECEGTEDNRKTISQLLVQVKENQREKEKLEIELNSLRSTTEDQRRHIEIRDQALNNAQAKVVKLEEELKKKQVYVEKVERMQQALAQLQAACEKREQLEHRLRTRLERELESLRMQQRQGGSQSTVGPEFSTAALMEHLREKEERILALEADMTKWEQKYLEESVMRQFALDAAASVATQRDTSSAIISHSPSSSYDTSVEARIQKEEEEILMANRRCLDMESRIKNLHAQIIEKDAMIKVLHQRSRKEPASKLDTPAMRPSKSLMSIATGTGGSSGSGLLSHSLGLSGSSPITEERREDRSWKGSLGVLLGPEFRGDSLRTESISSSPSPVLPSTPMPLATHSKTGSRDSCTQTEKSQENSKPSTPALQNVPGPSRISSPSPVYIPDRIADVPVFHSSTLERRAPVQSLPPASVAAQDMDSDMVEILI", "length": 1009 }, "evidence": [ { "id": "A0A8V0YNW6", "url": "https://omabrowser.org/oma/group/A0A8V0YNW6/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q4VCS5-1", "protein_name": "Angiomotin", "gene_name": "AMOT", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRNSEEQPSGGTTVLQRLLQEQLRYGNPSENRSLLAIHQQATGNGPPFPSGSGNPGPQSDVLSPQDHHQQLVAHAARQEPQGQEIQSENLIMEKQLSPRMQNNEELPTYEEAKVQSQYFRGQQHASVGAAFYVTGVTNQKMRTEGRPSVQRLNPGKMHQDEGLRDLKQGHVRSLSERLMQMSLATSGVKAHPPVTSAPLSPPQPNDLYKNPTSSSEFYKAQGPLPNQHSLKGMEHRGPPPEYPFKGMPPQSVVCKPQEPGHFYSEHRLNQPGRTEGQLMRYQHPPEYGAARPAQDISLPLSARNSQPHSPTSSLTSGGSLPLLQSPPSTRLSPARHPLVPNQGDHSAHLPRPQQHFLPNQAHQGDHYRLSQPGLSQQQQQQQQQHHHHHHHQQQQQQQPQQQPGEAYSAMPRAQPSSASYQPVPADPFAIVSRAQQMVEILSDENRNLRQELEGCYEKVARLQKVETEIQRVSEAYENLVKSSSKREALEKAMRNKLEGEIRRMHDFNRDLRERLETANKQLAEKEYEGSEDTRKTISQLFAKNKESQREKEKLEAELATARSTNEDQRRHIEIRDQALSNAQAKVVKLEEELKKKQVYVDKVEKMQQALVQLQAACEKREQLEHRLRTRLERELESLRIQQRQGNCQPTNVSEYNAAALMELLREKEERILALEADMTKWEQKYLEENVMRHFALDAAATVAAQRDTTVISHSPNTSYDTALEARIQKEEEEILMANKRCLDMEGRIKTLHAQIIEKDAMIKVLQQRSRKEPSKTEQLSCMRPAKSLMSISNAGSGLLSHSSTLTGSPIMEEKRDDKSWKGSLGILLGGDYRAEYVPSTPSPVPPSTPLLSAHSKTGSRDCSTQTERGTESNKTAAVAPISVPAPVAAAATAAAITATAATITTTMVAAAPVAVAAAAAPAAAAAPSPATAAATAAAVSPAAAGQIPAAASVASAAAVAPSAAAAAAVQVAPAAPAPVPAPALVPVPAPAAAQASAPAQTQAPTSAPAVAPTPAPTPTPAVAQAEVPASPATGPGPHRLSIPSLTCNPDKTDGPVFHSNTLERKTPIQILGQEPDAEMVEYLI", "length": 1084 }, "evidence": [ { "id": "A0A8V0YNW6", "url": "https://omabrowser.org/oma/group/A0A8V0YNW6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8VHG2-1", "protein_name": "Angiomotin", "gene_name": "Amot", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRSSDDQPSGGTTVLQRLLQEQLRYGNPSENRSLLAIHQQATGNSSPFSTGSGNQGPQNDVLSSQDHHQQQLVAHPARQEPQGQEIQSENGVMEKQLSPRMQNNEELPTYEEAKVQSQYFRGQQHASVGAAFYVTGVTNQKMRTEGRPSVQRLTPGKMHQDEGLRDLKQGHVRSLSERLMQMSLATSGVKAHPPVTSAPLSPPQPNDLYKNATSSSEFYKAQGPPPSQHSLKGMEHRGPPPEYPFKGVPSQSVVCKSQEPGHFYSEHRLNQPGRTEGQLMRYQHPPEYGAARATQDISSLSLSARNSQPHSPTSSLTAGASSLPLLQSPPSTRLPPGQHLVSNQGDHSAHLSRHQQHLLSSQSHQGDHYRHAQASLTSAQQQPGEAYSAMPRAQQSASYQPMPADPFAMVSRAQQMVEILSDENRNLRQELDGCYEKVARLQKVETEIQRVSEAYENLVKSSSKREALEKAMRNKLEGEIRRMHDFNRDLRDRLETANKQLAEKEYEGSEDTRKTISQLFAKHKENQREKEKLEAELATARSTNEDQRRHIEIRDQALSNAQAKVVKLEEELKKKQVYVDKVEKMQQALVQLQAACEKREQLEHRLRTRLERELESLRIQQRQGNSQPTNASEYNAAALMELLREKEERILALEADMTKWEQKYLEENVMRHFALDAAATVAAQRDTTVISHSPNTSYDTALEARIQKEEEEILMANKRCLDMEGRIKTLHAQIIEKDAMIKVLQQRSRKEPSKTEQLSSMRPAKSLMSISNAGSGLLAHSSTLTGAPIMEEKRDDKSWKGSLGVLLGGDYRVEPVPSTPSPVPPSTPLLSAHSKTGSRDCSTQTERGPESTKTAAVTPISAPMAGPVAAAAPAAAINATAATNTATAATNTTIMVAAAPVAVAAVAAPAAAAATPSPANAAALAAAAAPATSVSAATSVSAANSISPAAPVAPAAVVPPAAPVSPAAAVQIPAAASLTPATVSPTAATATAAVAAATTAAITAAAAAATTAIQVAPATSAPVPSPASIPAPATAQASAPTPTQASTPAPTEPPSPVPTPTPALVQTEGPANPGASSGPRRLSTPNLMCNPDKPDAPAFHSSTLERKTPIQILGQEPDAEMVEYLI", "length": 1126 }, "evidence": [ { "id": "A0A8V0YNW6", "url": "https://omabrowser.org/oma/group/A0A8V0YNW6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 10, "go_terms": [ { "name": "anchoring junction", "id": "GO:0070161", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070161", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNW6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNW6" } ], "pmid": "" }, { "name": "actin filament", "id": "GO:0005884", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005884", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNW6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNW6" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNW6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNW6" } ], "pmid": "" }, { "name": "bicellular tight junction", "id": "GO:0005923", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005923", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNW6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNW6" } ], "pmid": "" }, { "name": "lamellipodium", "id": "GO:0030027", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030027", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNW6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNW6" } ], "pmid": "" }, { "name": "external side of plasma membrane", "id": "GO:0009897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009897", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNW6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNW6" } ], "pmid": "" }, { "name": "cytoplasmic vesicle", "id": "GO:0031410", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031410", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNW6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNW6" } ], "pmid": "" }, { "name": "endocytic vesicle", "id": "GO:0030139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030139", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNW6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNW6" } ], "pmid": "" }, { "name": "ruffle", "id": "GO:0001726", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001726", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNW6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNW6" } ], "pmid": "" }, { "name": "COP9 signalosome", "id": "GO:0008180", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008180", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNW6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNW6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNW6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNW6" } ], "pmid": "" }, { "name": "angiogenesis", "id": "GO:0001525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001525", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNW6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNW6" } ], "pmid": "" }, { "name": "hippo signaling", "id": "GO:0035329", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035329", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNW6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNW6" } ], "pmid": "" }, { "name": "actin cytoskeleton organization", "id": "GO:0030036", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030036", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNW6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNW6" } ], "pmid": "" }, { "name": "regulation of cell migration", "id": "GO:0030334", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030334", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNW6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNW6" } ], "pmid": "" }, { "name": "establishment of cell polarity involved in ameboidal cell migration", "id": "GO:0003365", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003365", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNW6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNW6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "angiostatin binding", "id": "GO:0043532", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043532", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNW6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNW6" } ], "pmid": "" }, { "name": "signaling receptor activity", "id": "GO:0038023", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038023", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNW6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNW6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 121, "end_pos": 123, "annotation": "n_glycosylation_sequon" }, { "start_pos": 320, "end_pos": 322, "annotation": "n_glycosylation_sequon" }, { "start_pos": 497, "end_pos": 499, "annotation": "n_glycosylation_sequon" }, { "start_pos": 703, "end_pos": 705, "annotation": "n_glycosylation_sequon" }, { "start_pos": 708, "end_pos": 710, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YNW6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNW6" }, { "id": "PF12240", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12240" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Angiomotin C-terminal", "eco_id": "ECO_0000259", "start_pos": 651, "end_pos": 855, "start_aa": "Tyr", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 892, 935 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 121, "end_pos": 123 }, { "start_pos": 320, "end_pos": 322 }, { "start_pos": 497, "end_pos": 499 }, { "start_pos": 703, "end_pos": 705 }, { "start_pos": 708, "end_pos": 710 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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"glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YPV0-1", "uniprot_ac": "A0A8V0YPV0", "uniprot_id": "A0A8V0YPV0_CHICK", "mass": { "chemical_mass": 56213.0, "monoisotopic_mass": 56213.0 }, "refseq": {}, "gene_names": [ { "name": "TRIT1", "type": "recommended", "evidence": [ { "id": "A0A8V0YPV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPV0" } ] } ], "protein_names": [ { "name": "tRNA dimethylallyltransferase", "type": "recommended", "evidence": [ { "id": "A0A8V0YPV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPV0/entry#names_and_taxonomy" } ] }, { "name": "2.5.1.75", "type": "synonym", "evidence": [ { "id": "A0A8V0YPV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPV0/entry#names_and_taxonomy" } ] }, { "name": "Isopentenyl-diphosphate:tRNA isopentenyltransferase", "type": "synonym", "evidence": [ { "id": "A0A8V0YPV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPV0/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 of both cytosolic and mitochondrial tRNAs, leading to the formation of N6-(dimethylallyl)adenosine (i6A37). Mediates modification of a limited subset of tRNAs: tRNA(Ser)(AGA), tRNA(Ser)(CGA), tRNA(Ser)(UGA), as well as partial modification of the selenocysteine tRNA(Ser)(UCA). TRIT1 is therefore required for selenoprotein expression.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPV0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPV0#function" }, { "database": "UniProtKB", "id": "ARBA00057810", "url": "https://www.uniprot.org/uniprotkb/ARBA00057810#function" }, { "database": "UniProtKB", "id": "E1C6R1", "url": "https://www.uniprot.org/uniprotkb/E1C6R1#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPV0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPV0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TRIT1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPV0", "locus": { "chromosome": "23", "start_pos": 5879826, "end_pos": 5893824, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010016534", "url": "https://www.ensembl.org/id/ENSGALG00010016534" } ] } } ], "crossref": [ { "id": "A0A8V0YPV0", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YPV0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000003851", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000003851", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "419678", "url": "https://www.ncbi.nlm.nih.gov/gene/419678", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR018022", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018022", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR030666", "url": "https://www.ebi.ac.uk/interpro/entry/IPR030666", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039657", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039657", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:419678", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419678", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YPV0", "url": "https://www.orthodb.org/?gene=A0A8V0YPV0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z354", "url": "https://www.orthodb.org/?gene=A0A8V0Z354", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1C6R1", "url": "https://www.orthodb.org/?gene=E1C6R1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11088", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11088", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11088:SF89", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11088:SF89", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01715", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01715", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "26482", "url": "https://www.rhea-db.org/rhea/26482", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YPV0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPV0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YPV0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPV0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z354", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z354", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z354-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z354-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C6R1", "url": "https://www.uniprot.org/uniprotkb/E1C6R1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C6R1-1", "url": "https://www.uniprot.org/uniprotkb/E1C6R1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MATAGPGRVMAAALCLGRVSPPRPLVVILGATGTGKSALAVQLGLRLGGEIVSADSMQVYKGLDIITNKVSPQEQRLCRHHMISFVDPLVSNYTVVDFRDKAVALIEDIFARDKIPIVVGGTNYYIESLLWKVLVNTKEKSTMVSGTFTDRKVELEQLDAVDLHRRLSQVDPEMAAKLHPNDKRKVARSLQVFEETGIPHSEILQQQQEEEGGGPLGGPLKYPHSCILWLHADQAALDQRLEQRVDDMLAAGLLEELRDFHQRYNQAKVTENRQDYQHGIFQSIGFKEFHEYLVSEGNCSPETSALLLQKGIQALKQVSKRYARRQNKWVRNRFLKRPGPNVPPVYGLEVSDLLRWEEDVLKPALEIVESFIQGRKPPVEPVKMECDVNENKRSHRVCELCNRVIIGDREWAAHTRSKAHLHHLKKRKKLEAAGHAAETVRDSQKVESEPLHVAPSCCVLCFSCPACGGLALGQGCWGILCPVFTPATDAALSLERWSFSFGM", "length": 503, "header": "tr|A0A8V0YPV0-1|A0A8V0YPV0_CHICK Isoform 1 of tRNA dimethylallyltransferase OS=Gallus gallus OX=9031 GN=TRIT1 PE=3 SV=1 CANONICAL=A0A8V0YPV0-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YPV0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPV0/entry#A0A8V0YPV0-1", "sequence": { "sequence": "MATAGPGRVMAAALCLGRVSPPRPLVVILGATGTGKSALAVQLGLRLGGEIVSADSMQVYKGLDIITNKVSPQEQRLCRHHMISFVDPLVSNYTVVDFRDKAVALIEDIFARDKIPIVVGGTNYYIESLLWKVLVNTKEKSTMVSGTFTDRKVELEQLDAVDLHRRLSQVDPEMAAKLHPNDKRKVARSLQVFEETGIPHSEILQQQQEEEGGGPLGGPLKYPHSCILWLHADQAALDQRLEQRVDDMLAAGLLEELRDFHQRYNQAKVTENRQDYQHGIFQSIGFKEFHEYLVSEGNCSPETSALLLQKGIQALKQVSKRYARRQNKWVRNRFLKRPGPNVPPVYGLEVSDLLRWEEDVLKPALEIVESFIQGRKPPVEPVKMECDVNENKRSHRVCELCNRVIIGDREWAAHTRSKAHLHHLKKRKKLEAAGHAAETVRDSQKVESEPLHVAPSCCVLCFSCPACGGLALGQGCWGILCPVFTPATDAALSLERWSFSFGM", "length": 503, "header": "tr|A0A8V0YPV0-1|A0A8V0YPV0_CHICK Isoform 1 of tRNA dimethylallyltransferase OS=Gallus gallus OX=9031 GN=TRIT1 PE=3 SV=1 CANONICAL=A0A8V0YPV0-1" }, "locus": { "chromosome": "23", "start_pos": 5893817, "end_pos": 5880017, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010039817.1", "url": "https://www.ensembl.org/id/ENSGALT00010039817.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023037.1", "url": "https://www.ensembl.org/id/ENSGALP00010023037.1" } ] } }, { "isoform_ac": "A0A8V0Z354-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPV0/entry#A0A8V0Z354-1", "sequence": { "sequence": "HGGGVVLGPAAGLLEELRDFHQRYNQAKVTENRQDYQHGIFQSIGFKEFHEYLVSEGNCSPETSALLLQKGIQALKQVSKRYARRQNKWVRNRFLKRPGPNVPPVYGLEVSDLLRWEEDVLKPALEIVESFIQGRKPPVEPVKMECDVNENKRSHRVCELCNRVIIGDREWAGRVLAGGFDTVITAMHREQCEAVSLAGSAWPDDPQHMILGFQGLFTACA", "length": 221, "header": "tr|A0A8V0Z354-1|A0A8V0Z354_CHICK Computationally mapped isoform of tRNA isopentenyltransferase 1 OS=Gallus gallus OX=9031 GN=TRIT1 PE=3 SV=1 CANONICAL=A0A8V0YPV0-1" }, "locus": { "chromosome": "23", "start_pos": 5893791, "end_pos": 5882527, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010039810.1", "url": "https://www.ensembl.org/id/ENSGALT00010039810.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023033.1", "url": "https://www.ensembl.org/id/ENSGALP00010023033.1" } ] } }, { "isoform_ac": "E1C6R1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPV0/entry#E1C6R1-1", "sequence": { "sequence": "MATAGPGRVMAAALCLGRVSPPRPLVVILGATGTGKSALAVQLGLRLGGEIVSADSMQVYKGLDIITNKVSPQEQRLCRHHMISFVDPLVSNYTVVDFRDKAVALIEDIFARDKIPIVVGGTNYYIESLLWKVLVNTKEKSTMVSGTFTDRKVELEQLDAVDLHRRLSQVDPEMAAKLHPNDKRKVARSLQVFEETGIPHSEILQQQQEEEGGGPLGGPLKYPHSCILWLHADQAALDQRLEQRVDDMLAAGLLEELRDFHQRYNQAKVTENRQDYQHGIFQSIGFKEFHEYLVSEGNCSPETSALLLQKGIQALKQVSKRYARRQNKWVRNRFLKRPGPNVPPVYGLEVSDLLRWEEDVLKPALEIVESFIQGRKPPVEPVKMECDVNENKRSHRVCELCNRVIIGDREWAAHTRSKAHLHHLKKRKKLEAAGHAAETVRDSRSAETAGKDSSMPLL", "length": 458, "header": "tr|E1C6R1-1|A0A8V0YPV0_CHICK Computationally mapped isoform of tRNA dimethylallyltransferase OS=Gallus gallus OX=9031 GN=TRIT1 PE=3 SV=4 CANONICAL=A0A8V0YPV0-1" }, "locus": { "chromosome": "23", "start_pos": 5893817, "end_pos": 5880335, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010039821.1", "url": "https://www.ensembl.org/id/ENSGALT00010039821.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023041.1", "url": "https://www.ensembl.org/id/ENSGALP00010023041.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "gga:419678", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419678", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPV0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPV0" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPV0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPV0" } ], "pmid": "" }, { "name": "tRNA dimethylallyltransferase activity", "id": "GO:0052381", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0052381", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPV0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPV0" } ], "pmid": "" }, { "name": "transferase activity", "id": "GO:0016740", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016740", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPV0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPV0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPV0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPV0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "tRNA modification", "id": "GO:0006400", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006400", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPV0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPV0" } ], "pmid": "" }, { "name": "mitochondrial tRNA modification", "id": "GO:0070900", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070900", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPV0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPV0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 298, "end_pos": 300, "annotation": "n_glycosylation_sequon" }, { "start_pos": 92, "end_pos": 94, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "26482", "name": "", "equation": "adenosine(37) in tRNA + dimethylallyl diphosphate = N(6)-dimethylallyladenosine(37) in tRNA + diphosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YPV0-1" ], "evidence": [ { "id": "26482", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/26482" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A8V0YPV0", "gene_name": "TRIT1", "activity": [ { "ec_number": "2.5.1.75", "activity": "adenosine(37) in tRNA + dimethylallyl diphosphate = N(6)-dimethylallyladenosine(37) in tRNA + diphosphate.", "evidence": [ { "id": "A0A8V0YPV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPV0" } ] }, { "ec_number": "2.5.1.75", "activity": "", "evidence": [ { "id": "A0A8V0YPV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPV0" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.5.1.75", "ec_name": "adenosine(37) in tRNA + dimethylallyl diphosphate = N(6)-dimethylallyladenosine(37) in tRNA + diphosphate.", "evidence": [ { "id": "2.5.1.75", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:2.5.1.75" }, { "id": "2.5.1.75", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.5.1.75" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 298, "end_pos": 300 }, { "start_pos": 92, "end_pos": 94 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { 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"field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YR97-1", "uniprot_ac": "A0A8V0YR97", "uniprot_id": "A0A8V0YR97_CHICK", "mass": { "chemical_mass": 97279.0, "monoisotopic_mass": 97279.0 }, "refseq": {}, "gene_names": [ { "name": "PACS2", "type": "recommended", "evidence": [ { "id": "A0A8V0YR97", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YR97" } ] } ], "protein_names": [ { "name": "Phosphofurin acidic cluster sorting protein 2", "type": "synonym", "evidence": [ { "id": "A0A8V0YR97", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YR97/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YR97", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YR97" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PACS2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YR97", "locus": { "chromosome": "8", "start_pos": 4085466, "end_pos": 4149691, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013265", "url": "https://www.ensembl.org/id/ENSGALG00010013265" } ] } } ], "crossref": [ { "id": "A0A8V0YR97", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YR97", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR019381", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019381", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057541", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057541", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YD29", "url": "https://www.orthodb.org/?gene=A0A8V0YD29", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YLD3", "url": "https://www.orthodb.org/?gene=A0A8V0YLD3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YR97", "url": "https://www.orthodb.org/?gene=A0A8V0YR97", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13280", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13280", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13280:SF15", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13280:SF15", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10254", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10254", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25332", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25332", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YD29", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD29", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YD29-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD29-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLD3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLD3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLD3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLD3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YR97", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YR97", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YR97-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YR97-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLSPSKCSLLEGRSANSVNQNNAALPGQRMLCSLTLKKLVVLKELDKELISVVIAVKMQGSKRILRSHEIVLPPSGHVETELALTFSLQYPHFLKREGNKLQIMLQRRKRYKNRTILGYKTLAVGSINMAEVMQHPTEGGQVLSLFSNIKEAAVKVAEIWIFSLSSQPIDHEDSTMQASQKIKSTDNYSEEEYESFSSEQEASDDAVQGQDLDDDEYELGKPKKQRRSIVRTTSITRQQNFKQKVVALLKRFKVSDEVLDSEQDPAEHVPEVEEDLDLLYDTLDIENPSDSGPEMEDDDSVLSTPKPKLKPYFEGLSHSSSQTEIGSIHSIRSQREPSSPQVEVPEKTKSLGTKHTDDSISDTVSFESNQQAEVQEAELPAPDVFVEKLPPSGKITKTESLIIPSTSRSEGKQTGRRGRSTSLKERQPVRPQNERANSLDNERSPDTRHHLQIPRKTVYDQLNHILVSDDQLPENIILVNTSDWQGQYLSDVLQKHTLPVVCTCSSADIQAAFSTIVSRIQRYCNCNSQPPSPIKIAVAGAQNYLSAVLRLFVEQLSHKTPDWLGYMRFLIIPLGSHPVAKYLGSVDYRYNNFFQDVAWRDLFNKLEAQTTVTETLDVVSRITQYIAGANCAHQLPIAEAMLTYKQKSPDEESSQKFIPFVGVVKVGIVEQSSATSGDSDDAAPSSSSVLSSTPPSVSPAVKEASPTPPSSPSVTGSFSSSSQGLGAELMGLQVDYWIAAPPVDRKRDPEKKDPSTTKNTLKCTFRSLQVSRLPASGEIATTPTMSMTVVTKEKNKKVMFLPKKTKDKEVESKSQCIEGISRLICTAKHQQNMLRVLIDGVEWNDVKFFQLAAQWSSHVKHFPICIFGHSKSNF", "length": 874, "header": "tr|A0A8V0YR97-1|A0A8V0YR97_CHICK Isoform 1 of Phosphofurin acidic cluster sorting protein 2 OS=Gallus gallus OX=9031 GN=PACS2 PE=1 SV=1 CANONICAL=A0A8V0YR97-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YD29-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YR97/entry#A0A8V0YD29-1", "sequence": { "sequence": "MAAAAERGRLSFPGGAGALGRPVPMNLFATWEIDGSSPSCVPRLCSLTLKKLVVLKELDKELISVVIAVKMQGSKRILRSHEIVLPPSGHVETELALTFSLQYPHFLKREGNKLQIMLQRRKRYKNRTILGYKTLAVGSINMAEVMQHPTEGGQVLSLFSNIKEAAVKVAEIWIFSLSSQPIDHEDSTMQASQKIKSTDNYSEEEYESFSSEQEASDDAVQGQDLDDDEYELGKPKKQRRSIVRTTSITRQQNFKQKVVALLKRFKVSDEVLDSEQDPAEHVPEVEEDLDLLYDTLDIENPSDSGPEMEDDDSVLSTPKPKLKPYFEGLSHSSSQTEIGSIHSIRSQREPSSPQVEVPEKTKSLGTKHTDDSISDTVSFESNQQAEVQEAELPAPDVFVEKLPPSGKITKTESLIIPSTSRSEGKQTGRRGRSTSLKERQPVRPQNERANSLDNERSPDTRHHLQIPRKTVYDQLNHILVSDDQLPENIILVNTSDWQGQYLSDVLQKHTLPVVCTCSSADIQAAFSTIVSRIQRYCNCNSQPPSPIKIAVAGAQNYLSAVLRLFVEQLSHKTPDWLGYMRFLIIPLVTETLDVVSRITQYIAGANCAHQLPIAEAMLTYKQKSPDEESSQKFIPFVGVVKVGIVEQSSATSGDSDDAAPSSSSVLSSTPPSVSPAVKEASPTPPSSPSVTGSFSSSSQGLGAELMGLQVDYWIAAPPVDRKRDPEKKDPSTTKNTLKCTFRSLQVSRLPASGEIATTPTMSMTVVTKEKNKKVMFLPKKTKDKEVESKSQCIEGISRLICTAKHQQNMLRVLIDGVEWNDVKFFQLAAQWSSHVKHFPICIFGHSKSNF", "length": 850, "header": "tr|A0A8V0YD29-1|A0A8V0YR97_CHICK Computationally mapped isoform of Phosphofurin acidic cluster sorting protein 2 OS=Gallus gallus OX=9031 GN=PACS2 PE=1 SV=1 CANONICAL=A0A8V0YR97-1" }, "locus": { "chromosome": "8", "start_pos": 4149636, "end_pos": 4085663, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031890.1", "url": "https://www.ensembl.org/id/ENSGALT00010031890.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018692.1", "url": "https://www.ensembl.org/id/ENSGALP00010018692.1" } ] } }, { "isoform_ac": "A0A8V0YLD3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YR97/entry#A0A8V0YLD3-1", "sequence": { "sequence": "MWLLSNRVPALLGTGRLCCCRLCSLTLKKLVVLKELDKELISVVIAVKMQGSKRILRSHEIVLPPSGHVETELALTFSLQYPHFLKREGNKLQIMLQRRKRYKNRTILGYKTLAVGSINMAEVMQHPTEGGQVLSLFSNIKEAAVKVAEIWIFSLSSQPIDHEDSTMQASQKIKSTDNYSEEEYESFSSEQEASDDAVQGQDLDDDEYELGKPKKQRRSIVRTTSITRQQNFKQKVVALLKRFKVSDEVLDSEQDPAEHVPEVEEDLDLLYDTLDIENPSDSGPEMEDDDSVLSTPKPKLKPYFEGLSHSSSQTEIGSIHSIRSQREPSSPQVEVPEKTKSLGTKHTDDSISDTVSFESNQQAEVQEAELPAPDVFVEKLPPSGKITKTESLIIPSTSRSEGKQTGRRGRSTSLKERQPVRPQNERANSLDNERSPDTRHHLQIPRKTVYDQLNHILVSDDQLPENIILVNTSDWQGQYLSDVLQKHTLPVVCTCSSADIQAAFSTIVSRIQRYCNCNSQPPSPIKIAVAGAQNYLSAVLRLFVEQLSHKTPDWLGYMRFLIIPLGSHPVAKYLGSVDYRYNNFFQDVAWRDLFNKLEAQTTVTETLDVVSRITQYIAGANCAHQLPIAEAMLTYKQKSPDEESSQKFIPFVGVVKVGIVEQSSATSGDSDDAAPSSSSVLSSTPPSVSPAVKEASPTPPSSPSVTGSFSSSSQGLGAELMGLQVDYWIAAPPVDRKRDPEKKDPSTTKNTLKCTFRSLQVSRLPASGEIATTPTMSMTVVTKEKNKKVMFLPKKTKDKEVESKSQCIEGISRLICTAKHQQNMLRVLIDGVEWNDVKFFQLAAQWSSHVKHFPICIFGHSKSNF", "length": 865, "header": "tr|A0A8V0YLD3-1|A0A8V0YR97_CHICK Computationally mapped isoform of Phosphofurin acidic cluster sorting protein 2 OS=Gallus gallus OX=9031 GN=PACS2 PE=1 SV=1 CANONICAL=A0A8V0YR97-1" }, "locus": { "chromosome": "8", "start_pos": 4134532, "end_pos": 4085663, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031888.1", "url": "https://www.ensembl.org/id/ENSGALT00010031888.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018690.1", "url": "https://www.ensembl.org/id/ENSGALP00010018690.1" } ] } }, { "isoform_ac": "A0A8V0YR97-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YR97/entry#A0A8V0YR97-1", "sequence": { "sequence": "MLSPSKCSLLEGRSANSVNQNNAALPGQRMLCSLTLKKLVVLKELDKELISVVIAVKMQGSKRILRSHEIVLPPSGHVETELALTFSLQYPHFLKREGNKLQIMLQRRKRYKNRTILGYKTLAVGSINMAEVMQHPTEGGQVLSLFSNIKEAAVKVAEIWIFSLSSQPIDHEDSTMQASQKIKSTDNYSEEEYESFSSEQEASDDAVQGQDLDDDEYELGKPKKQRRSIVRTTSITRQQNFKQKVVALLKRFKVSDEVLDSEQDPAEHVPEVEEDLDLLYDTLDIENPSDSGPEMEDDDSVLSTPKPKLKPYFEGLSHSSSQTEIGSIHSIRSQREPSSPQVEVPEKTKSLGTKHTDDSISDTVSFESNQQAEVQEAELPAPDVFVEKLPPSGKITKTESLIIPSTSRSEGKQTGRRGRSTSLKERQPVRPQNERANSLDNERSPDTRHHLQIPRKTVYDQLNHILVSDDQLPENIILVNTSDWQGQYLSDVLQKHTLPVVCTCSSADIQAAFSTIVSRIQRYCNCNSQPPSPIKIAVAGAQNYLSAVLRLFVEQLSHKTPDWLGYMRFLIIPLGSHPVAKYLGSVDYRYNNFFQDVAWRDLFNKLEAQTTVTETLDVVSRITQYIAGANCAHQLPIAEAMLTYKQKSPDEESSQKFIPFVGVVKVGIVEQSSATSGDSDDAAPSSSSVLSSTPPSVSPAVKEASPTPPSSPSVTGSFSSSSQGLGAELMGLQVDYWIAAPPVDRKRDPEKKDPSTTKNTLKCTFRSLQVSRLPASGEIATTPTMSMTVVTKEKNKKVMFLPKKTKDKEVESKSQCIEGISRLICTAKHQQNMLRVLIDGVEWNDVKFFQLAAQWSSHVKHFPICIFGHSKSNF", "length": 874, "header": "tr|A0A8V0YR97-1|A0A8V0YR97_CHICK Isoform 1 of Phosphofurin acidic cluster sorting protein 2 OS=Gallus gallus OX=9031 GN=PACS2 PE=1 SV=1 CANONICAL=A0A8V0YR97-1" }, "locus": { "chromosome": "8", "start_pos": 4129170, "end_pos": 4085663, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031886.1", "url": "https://www.ensembl.org/id/ENSGALT00010031886.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018688.1", "url": "https://www.ensembl.org/id/ENSGALP00010018688.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 707, "start_aa": "Thr", "end_pos": 707, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr707", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YR97", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YR97" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "protein localization to plasma membrane", "id": "GO:0072659", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072659", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YR97", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YR97" } ], "pmid": "" }, { "name": "endoplasmic reticulum calcium ion homeostasis", "id": "GO:0032469", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032469", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YR97", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YR97" } ], "pmid": "" }, { "name": "mitochondrion-endoplasmic reticulum membrane tethering", "id": "GO:1990456", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990456", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YR97", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YR97" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "transmembrane transporter binding", "id": "GO:0044325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044325", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YR97", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YR97" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 113, "end_pos": 115, "annotation": "n_glycosylation_sequon" }, { "start_pos": 187, "end_pos": 189, "annotation": "n_glycosylation_sequon" }, { "start_pos": 480, "end_pos": 482, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YR97", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YR97" }, { "id": "PF10254", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10254" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Phosphofurin acidic cluster sorting protein 1/2 C-terminal", "eco_id": "ECO_0000259", "start_pos": 458, "end_pos": 870, "start_aa": "Val", "end_aa": "Ser", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0YR97", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YR97" }, { "id": "PF25332", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25332" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Phosphofurin acidic cluster sorting protein 1/2 N-terminal C2", "eco_id": "ECO_0000259", "start_pos": 28, "end_pos": 169, "start_aa": "Gln", "end_aa": "Ile", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 707 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 113, "end_pos": 115 }, { "start_pos": 187, "end_pos": 189 }, { "start_pos": 480, "end_pos": 482 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", 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"http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10910", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10910:SF58", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10910:SF58", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00035", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00035", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02137", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02137", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-75102", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-75102", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-77042", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-77042", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YEP2", "url": 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"MDNVPPKDGSAQGTGEGAQLSNGGSSSSSSRKRPLEEGNNGHSKFRPKKRKKTPGPVLPKNALMQLNEIKPGLQYKLLSQTGPVHAPVFVMAVEVNGQVFEGSGPTKKKAKLHAAEKALRSFVQFPNASEAHLAMGRTLSVNTDFTSDQADFPDTLFNGFETPVPSDASFYLGSNGDGSFGSSREYGLSSAAVASSLTQLPLPASLPYPTASGKNPVMILNELRPGLKYEFLSESGESHAKNFVMAVAVDGQTFEGSGRNKKLAKARAAQSALASLFNMQLDQTPSRQPIPSEGLQLHLPQVLADAVARLVVDKFSDLTENFTSPHARRKVLAGIVMTTGTDVKDALVISVSTGTKCINGEYMSDRGLALNDCHAEIISRRCLLKFLYTQLELYLSNKDDQEKSIFIKSERGGFKLKENVQFHLYISTSPCGDARIFSPHEAAQEDQGDRHPNRKARGQLRTKIESGEGTIPVRSTTTIQTWDGVLQGERLLTMSCSDKIARWNVLGIQGALLSLFVEPIYFSSIILGSLYHGDHLSRAVYQRIAEIEDLPPLYTLNRPLLSGKYLMERAVPVTNNIVKALKLKSLILPITVCIALFCRARLLSSLFIFQEKKKKDWYFKACLKFDMDFKNKHSELVIYLIYFIRIP", "length": 647, "header": "tr|A0A8V0YMW8-1|A0A8V0YMW8_CHICK Isoform 1 of Adenosine deaminase, RNA specific B1 OS=Gallus gallus OX=9031 GN=ADARB1 PE=4 SV=1 CANONICAL=A0A8V0YMW8-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YEP2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMW8/entry#A0A8V0YEP2-1", "sequence": { "sequence": "MDVDDEENMSSSSTDVKENRNMDNVPPKDGSAQGTGEGAQLSNGGSSSSSSRKRPLEEGNNGHSKFRPKKRKKTPGPVLPKNALMQLNEIKPGLQYKLLSQTGPVHAPVFVMAVEVNGQVFEGSGPTKKKAKLHAAEKALRSFVQFPNASEAHLAMGRTLSVNTDFTSDQADFPDTLFNGFETPVPSDASFYLGSNGDGSFGSSREYGLSSAAVASSLTQLPLPASLPYPTASGKNPVMILNELRPGLKYEFLSESGESHAKNFVMAVAVDGQTFEGSGRNKKLAKARAAQSALASLFNMQLDQTPSRQPIPSEGLQLHLPQVLADAVARLVVDKFSDLTENFTSPHARRKVLAGIVMTTGTDVKDALVISVSTGTKCINGEYMSDRGLALNDCHAEIISRRCLLKFLYTQLELYLSNKDDQEKSIFIKSERGGFKLKENVQFHLYISTSPCGDARIFSPHEAAQEDQGDRHPNRKARGQLRTKIESGEGTIPVRSTTTIQTWDGVLQGERLLTMSCSDKIARTESISRLRS", "length": 532, "header": "tr|A0A8V0YEP2-1|A0A8V0YMW8_CHICK Computationally mapped isoform of Adenosine deaminase, RNA specific B1 OS=Gallus gallus OX=9031 GN=ADARB1 PE=4 SV=1 CANONICAL=A0A8V0YMW8-1" }, "locus": { "chromosome": "7", "start_pos": 7348435, "end_pos": 7322318, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032568.1", "url": "https://www.ensembl.org/id/ENSGALT00010032568.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019293.1", "url": "https://www.ensembl.org/id/ENSGALP00010019293.1" } ] } }, { "isoform_ac": "A0A8V0YMW8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMW8/entry#A0A8V0YMW8-1", "sequence": { "sequence": "MDNVPPKDGSAQGTGEGAQLSNGGSSSSSSRKRPLEEGNNGHSKFRPKKRKKTPGPVLPKNALMQLNEIKPGLQYKLLSQTGPVHAPVFVMAVEVNGQVFEGSGPTKKKAKLHAAEKALRSFVQFPNASEAHLAMGRTLSVNTDFTSDQADFPDTLFNGFETPVPSDASFYLGSNGDGSFGSSREYGLSSAAVASSLTQLPLPASLPYPTASGKNPVMILNELRPGLKYEFLSESGESHAKNFVMAVAVDGQTFEGSGRNKKLAKARAAQSALASLFNMQLDQTPSRQPIPSEGLQLHLPQVLADAVARLVVDKFSDLTENFTSPHARRKVLAGIVMTTGTDVKDALVISVSTGTKCINGEYMSDRGLALNDCHAEIISRRCLLKFLYTQLELYLSNKDDQEKSIFIKSERGGFKLKENVQFHLYISTSPCGDARIFSPHEAAQEDQGDRHPNRKARGQLRTKIESGEGTIPVRSTTTIQTWDGVLQGERLLTMSCSDKIARWNVLGIQGALLSLFVEPIYFSSIILGSLYHGDHLSRAVYQRIAEIEDLPPLYTLNRPLLSGKYLMERAVPVTNNIVKALKLKSLILPITVCIALFCRARLLSSLFIFQEKKKKDWYFKACLKFDMDFKNKHSELVIYLIYFIRIP", "length": 647, "header": "tr|A0A8V0YMW8-1|A0A8V0YMW8_CHICK Isoform 1 of Adenosine deaminase, RNA specific B1 OS=Gallus gallus OX=9031 GN=ADARB1 PE=4 SV=1 CANONICAL=A0A8V0YMW8-1" }, "locus": { "chromosome": "7", "start_pos": 7359147, "end_pos": 7327352, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032550.1", "url": "https://www.ensembl.org/id/ENSGALT00010032550.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019281.1", "url": "https://www.ensembl.org/id/ENSGALP00010019281.1" } ] } }, { "isoform_ac": "A0A8V0YSW9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMW8/entry#A0A8V0YSW9-1", "sequence": { "sequence": "MDVDDEENMSSSSTDVKENRNMDNVPPKDGSAQGTGEGAQLSNGGSSSSSSRKRPLEEGNNGHSKFRPKKRKKTPGPVLPKNALMQLNEIKPGLQYKLLSQTGPVHAPVFVMAVEVNGQVFEGSGPTKKKAKLHAAEKALRSFVQFPNASEAHLAMGRTLSVNTDFTSDQADFPDTLFNGFETPVPSDASFYLGSNGDGSFGSSREYGLSSAAVASSLTQLPLPASLPYPTASGKNPVMILNELRPGLKYEFLSESGESHAKNFVMAVAVDGQTFEGSGRNKKLAKARAAQSALASLFNMQLDQTPSRQPIPSEGLQLHLPQVLADAVARLVVDKFSDLTENFTSPHARRKVLAGIVMTTGTDVKDALVISVSTGTKCINGEYMSDRGLALNDCHAEIISRRCLLKFLYTQLELYLSNKDDQEKSIFIKSERGGFKLKENVQFHLYISTSPCGDARIFSPHEAAQEDQGDRHPNRKARGQLRTKIESGEGTIPVRSTTTIQTWDGVLQGERLLTMSCSDKIARWNVLGIQGALLSLFVEPIYFSSIILGSLYHGDHLSRAVYQRIAEIEDLPPLYTLNRPLLSG", "length": 584, "header": "tr|A0A8V0YSW9-1|A0A8V0YSW9_CHICK Computationally mapped isoform of Adenosine deaminase, RNA specific B1 OS=Gallus gallus OX=9031 GN=ADARB1 PE=4 SV=1 CANONICAL=A0A8V0YMW8-1" }, "locus": { "chromosome": "7", "start_pos": 7358069, "end_pos": 7322318, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032563.1", "url": "https://www.ensembl.org/id/ENSGALT00010032563.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019289.1", "url": "https://www.ensembl.org/id/ENSGALP00010019289.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 210, "start_aa": "Thr", "end_pos": 210, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr210", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "R-GGA-75102", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-75102", "resource": "Reactome", "description": "C6 deamination of adenosine" }, { "id": "R-GGA-77042", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-77042", "resource": "Reactome", "description": "Formation of editosomes by ADAR proteins" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 6, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMW8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMW8" } ], "pmid": "" }, { "name": "adenosine deaminase activity", "id": "GO:0004000", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004000", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMW8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMW8" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMW8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMW8" } ], "pmid": "" }, { "name": "tRNA-specific adenosine deaminase activity", "id": "GO:0008251", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008251", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMW8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMW8" } ], "pmid": "" }, { "name": "double-stranded RNA binding", "id": "GO:0003725", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003725", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMW8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMW8" } ], "pmid": "" }, { "name": "double-stranded RNA adenosine deaminase activity", "id": "GO:0003726", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003726", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMW8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMW8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMW8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMW8" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMW8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMW8" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMW8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMW8" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMW8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMW8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 7, "go_terms": [ { "name": "RNA processing", "id": "GO:0006396", "url": 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"tr|A0A8V0YN09-1|A0A8V0YN09_CHICK Isoform 1 of peptidylprolyl isomerase OS=Gallus gallus OX=9031 GN=FKBP1A PE=1 SV=1 CANONICAL=A0A8V0YN09-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YES6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN09/entry#A0A8V0YES6-1", "sequence": { "sequence": "MGVHVETIAPGDGRTFPKRGQTCVVHYTGMLEDGKKFDSSRDRNKPFKFVMGKQEVIRGWEEGVAQVPHIPLPRRDLRGTGQKSLRAALQISTPSVMGGVGVNITFCIATCQMAGTEQGRAEEHLRHVGDSALTFLY", "length": 137, "header": "tr|A0A8V0YES6-1|A0A8V0YN09_CHICK Computationally mapped isoform of peptidylprolyl isomerase OS=Gallus gallus OX=9031 GN=FKBP1A PE=1 SV=1 CANONICAL=A0A8V0YN09-1" }, "locus": { "chromosome": "20", "start_pos": 10170563, "end_pos": 10164690, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032618.1", "url": "https://www.ensembl.org/id/ENSGALT00010032618.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019329.1", "url": "https://www.ensembl.org/id/ENSGALP00010019329.1" } ] } }, { "isoform_ac": "A0A8V0YN09-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN09/entry#A0A8V0YN09-1", "sequence": { "sequence": "MGVHVETIAPGDGEPRPALPLSLSPHPPLLSVRCRSRCRSADGPCLPAGRTFPKRGQTCVVHYTGMLEDGKKFDSSRDRNKPFKFVMGKQEVIRGWEEGVAQMSVGQRAKMTISPDYAYGSTGHPGIIPPNATLIFDVELMKLE", "length": 144, "header": "tr|A0A8V0YN09-1|A0A8V0YN09_CHICK Isoform 1 of peptidylprolyl isomerase OS=Gallus gallus OX=9031 GN=FKBP1A PE=1 SV=1 CANONICAL=A0A8V0YN09-1" }, "locus": { "chromosome": "20", "start_pos": 10171132, "end_pos": 10164690, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032622.1", "url": "https://www.ensembl.org/id/ENSGALT00010032622.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019332.1", "url": "https://www.ensembl.org/id/ENSGALP00010019332.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "R-GGA-166208", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-166208", "resource": "Reactome", "description": "mTORC1-mediated signalling" }, { "id": "R-GGA-2025928", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2025928", "resource": "Reactome", "description": "Calcineurin activates NFAT" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "peptidyl-prolyl cis-trans isomerase activity", "id": "GO:0003755", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003755", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YN09", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN09" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YN09", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN09" } ], "pmid": "" }, { "name": "transmembrane transporter binding", "id": "GO:0044325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044325", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YN09", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN09" } ], "pmid": "" }, { "name": "FK506 binding", "id": "GO:0005528", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005528", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YN09", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN09" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "synapse", "id": "GO:0045202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045202", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YN09", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN09" } ], "pmid": "" }, { "name": "sarcoplasmic reticulum membrane", "id": "GO:0033017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033017", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YN09", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN09" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "protein folding", "id": "GO:0006457", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006457", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YN09", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN09" } ], "pmid": "" }, { "name": "heart trabecula formation", "id": "GO:0060347", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060347", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YN09", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN09" } ], "pmid": "" }, { "name": "regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion", "id": "GO:0010881", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010881", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YN09", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN09" } ], "pmid": "" }, { "name": "ventricular cardiac muscle tissue morphogenesis", "id": "GO:0055010", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055010", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YN09", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN09" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 131, "end_pos": 133, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "16237", "name": "", "equation": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V1ALG1-1", "F1NCD7-1", "A0A1D5NWE1-1", "A0A8V1A0X8-1", "A0A8V0YZ11-1", "A0A8V0X6B3-1", "A0A8V1AE18-1", "P24367-1", "E1C487-1", "A0A8V0X7D8-1", "A0A1D5PW44-1", "Q5ZLV2-1", "E1BXG9-1", "A0A3Q2U9P1-1", "A0A8V0XUB5-1", "A0A8V0XB51-1", "A0A8V0Y6V0-1", "A0A8V0Z0N7-1", "A0A8V0Z1Z7-1", "A0A8V0Z3A2-1", "A0A8V0ZS95-1", "A0A8V0ZU13-1", "A0A8V0ZEN0-1", "A0A8V0ZIR3-1", "A0A8V0ZPE3-1", "A0A8V0ZGR2-1", "A0A8V1A2D9-1", "A0A8V1AED8-1", "A0A8V1AII9-1", "A0A8V0YN09-1", "A0A8V0XMH4-1", "F1NAJ2-1" ], "evidence": [ { "id": "16237", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/16237" } ] }, { "id": "R-GGA-165692", "name": "Phosphorylation of 4E-BP1 by activated mTORC1", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, lysosomal membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YN09-1", "F1NUX4-1" ], "evidence": [ { "id": "R-GGA-165692", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-165692" } ] }, { "id": "R-GGA-165718", "name": "mTORC1 phosphorylation of RPS6KB1 (S6K)", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, lysosomal membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YN09-1", "A0A8V1AJA4-1", "F1NUX4-1" ], "evidence": [ { "id": "R-GGA-165718", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-165718" } ] }, { "id": "R-GGA-9679044", "name": "FKBP1A binds sirolimus", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YN09-1" ], "evidence": [ { "id": "R-GGA-9679044", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9679044" } ] }, { "id": "R-GGA-9690461", "name": "FKBP1A binds tacrolimus", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YN09-1" ], "evidence": [ { "id": "R-GGA-9690461", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9690461" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A1D5NWE1", "gene_name": "FKBP6", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "A0A1D5NWE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NWE1" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "A0A1D5NWE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NWE1" } ] } ] }, { "uniprot_ac": "A0A1D5PW44", "gene_name": "PPIL1", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "A0A1D5PW44", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PW44" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "A0A1D5PW44", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PW44" } ] } ] }, { "uniprot_ac": "A0A3Q2U9P1", "gene_name": "FKBP4", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "A0A3Q2U9P1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U9P1" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "A0A3Q2U9P1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U9P1" } ] } ] }, { "uniprot_ac": "A0A8V0X6B3", "gene_name": "", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "A0A8V0X6B3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X6B3" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "A0A8V0X6B3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X6B3" } ] } ] }, { "uniprot_ac": "A0A8V0X7D8", "gene_name": "PPIC", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "A0A8V0X7D8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X7D8" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "A0A8V0X7D8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X7D8" } ] } ] }, { "uniprot_ac": "A0A8V0XB51", "gene_name": "PIN1", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "A0A8V0XB51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XB51" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "A0A8V0XB51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XB51" } ] } ] }, { "uniprot_ac": "A0A8V0XMH4", "gene_name": "", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "A0A8V0XMH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMH4" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "A0A8V0XMH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMH4" } ] } ] }, { "uniprot_ac": "A0A8V0XUB5", "gene_name": "PPIL4", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "A0A8V0XUB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XUB5" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "A0A8V0XUB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XUB5" } ] } ] }, { "uniprot_ac": "A0A8V0Y6V0", "gene_name": "FKBP1B", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "A0A8V0Y6V0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y6V0" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "A0A8V0Y6V0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y6V0" } ] } ] }, { "uniprot_ac": "A0A8V0YN09", "gene_name": "FKBP1A", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "A0A8V0YN09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN09" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "A0A8V0YN09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN09" } ] } ] }, { "uniprot_ac": "A0A8V0YZ11", "gene_name": "FKBP3", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "A0A8V0YZ11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZ11" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "A0A8V0YZ11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZ11" } ] } ] }, { "uniprot_ac": "A0A8V0Z0N7", "gene_name": "PPIA", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "A0A8V0Z0N7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z0N7" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "A0A8V0Z0N7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z0N7" } ] } ] }, { "uniprot_ac": "A0A8V0Z1Z7", "gene_name": "PPIH", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "A0A8V0Z1Z7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1Z7" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "A0A8V0Z1Z7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1Z7" } ] } ] }, { "uniprot_ac": "A0A8V0Z3A2", "gene_name": "PPIE", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "A0A8V0Z3A2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3A2" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "A0A8V0Z3A2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3A2" } ] } ] }, { "uniprot_ac": "A0A8V0ZEN0", "gene_name": "PPIF", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "A0A8V0ZEN0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEN0" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "A0A8V0ZEN0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEN0" } ] } ] }, { "uniprot_ac": "A0A8V0ZGR2", "gene_name": "FKBP9", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "A0A8V0ZGR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGR2" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "A0A8V0ZGR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGR2" } ] } ] }, { "uniprot_ac": "A0A8V0ZIR3", "gene_name": "FKBP11", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "A0A8V0ZIR3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIR3" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "A0A8V0ZIR3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIR3" } ] } ] }, { "uniprot_ac": "A0A8V0ZPE3", "gene_name": "FKBP10", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "A0A8V0ZPE3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPE3" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "A0A8V0ZPE3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPE3" } ] } ] }, { "uniprot_ac": "A0A8V0ZS95", "gene_name": "", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "A0A8V0ZS95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS95" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "A0A8V0ZS95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS95" } ] } ] }, { "uniprot_ac": "A0A8V0ZU13", "gene_name": "PPIG", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "A0A8V0ZU13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU13" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "A0A8V0ZU13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU13" } ] } ] }, { "uniprot_ac": "A0A8V1A0X8", "gene_name": "FKBP7", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "A0A8V1A0X8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0X8" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "A0A8V1A0X8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0X8" } ] } ] }, { "uniprot_ac": "A0A8V1A2D9", "gene_name": "FKBP8", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "A0A8V1A2D9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2D9" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "A0A8V1A2D9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2D9" } ] } ] }, { "uniprot_ac": "A0A8V1AE18", "gene_name": "FKBP5", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "A0A8V1AE18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE18" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "A0A8V1AE18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE18" } ] } ] }, { "uniprot_ac": "A0A8V1AED8", "gene_name": "NKTR", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "A0A8V1AED8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AED8" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "A0A8V1AED8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AED8" } ] } ] }, { "uniprot_ac": "A0A8V1AII9", "gene_name": "FKBP15", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "A0A8V1AII9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AII9" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "A0A8V1AII9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AII9" } ] } ] }, { "uniprot_ac": "A0A8V1AJA4", "gene_name": "RPS6KB1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AJA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJA4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AJA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJA4" } ] } ] }, { "uniprot_ac": "A0A8V1ALG1", "gene_name": "PTPA", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "A0A8V1ALG1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALG1" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "A0A8V1ALG1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALG1" } ] } ] }, { "uniprot_ac": "E1BXG9", "gene_name": "PPID", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "E1BXG9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BXG9" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "E1BXG9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BXG9" } ] } ] }, { "uniprot_ac": "E1C487", "gene_name": "FKBP14", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "E1C487", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C487" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "E1C487", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C487" } ] } ] }, { "uniprot_ac": "F1NAJ2", "gene_name": "PPWD1", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "F1NAJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NAJ2" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "F1NAJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NAJ2" } ] } ] }, { "uniprot_ac": "F1NCD7", "gene_name": "PIN4", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "F1NCD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCD7" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "F1NCD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCD7" } ] } ] }, { "uniprot_ac": "F1NUX4", "gene_name": "MTOR", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NUX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NUX4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1NUX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NUX4" } ] } ] }, { "uniprot_ac": "P24367", "gene_name": "PPIB", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "P24367", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P24367" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "P24367", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P24367" } ] } ] }, { "uniprot_ac": "Q5ZLV2", "gene_name": "PPIL3", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "Q5ZLV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZLV2" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "Q5ZLV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZLV2" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YN09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN09" }, { "id": "PS50059", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50059" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PPIase FKBP-type", "eco_id": "ECO_0000259", "start_pos": 56, "end_pos": 144, "start_aa": "Gly", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "5.2.1.8", "ec_name": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "5.2.1.8", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:5.2.1.8" }, { "id": "5.2.1.8", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=5.2.1.8" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 131, "end_pos": 133 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YN22-1", "uniprot_ac": "A0A8V0YN22", "uniprot_id": "A0A8V0YN22_CHICK", "mass": { "chemical_mass": 64853.0, "monoisotopic_mass": 64853.0 }, "refseq": {}, "gene_names": [ { "name": "RANBP3L", "type": "recommended", "evidence": [ { "id": "A0A8V0YN22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN22" } ] } ], "protein_names": [ { "name": "Ran-binding protein 3-like", "type": "recommended", "evidence": [ { "id": "A0A8V0YN22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN22/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Nuclear export factor for BMP-specific SMAD1/5/8 that plays a critical role in terminating BMP signaling and regulating mesenchymal stem cell differentiation by blocking osteoblast differentiation to promote myogenic differention. Directly recognizes dephosphorylated SMAD1/5/8 and mediates their nuclear export in a Ran-dependent manner.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YEU1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEU1#function" }, { "database": "UniProtKB", "id": "ARBA00059866", "url": "https://www.uniprot.org/uniprotkb/ARBA00059866#function" }, { "database": "UniProtKB", "id": "A0A8V0YL73", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL73#function" }, { "database": "UniProtKB", "id": "A0A8V0YKL4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKL4#function" }, { "database": "UniProtKB", "id": "A0A8V0YN22", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN22#function" }, { "database": "UniProtKB", "id": "F1NGF7", "url": "https://www.uniprot.org/uniprotkb/F1NGF7#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YN22", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN22" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RANBP3L", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN22", "locus": { "chromosome": "Z", "start_pos": 11577616, "end_pos": 11618070, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013580", "url": "https://www.ensembl.org/id/ENSGALG00010013580" } ] } } ], "crossref": [ { "id": "A0A8V0YN22", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YN22", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000021304", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000021304", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd13180", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13180", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "770629", "url": "https://www.ncbi.nlm.nih.gov/gene/770629", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000156", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000156", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045255", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045255", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:770629", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:770629", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QMRFSSI", "url": "https://omabrowser.org/oma/group/QMRFSSI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YEU1", "url": "https://www.orthodb.org/?gene=A0A8V0YEU1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YKL4", "url": "https://www.orthodb.org/?gene=A0A8V0YKL4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YL73", "url": "https://www.orthodb.org/?gene=A0A8V0YL73", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YN22", "url": "https://www.orthodb.org/?gene=A0A8V0YN22", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NGF7", "url": "https://www.orthodb.org/?gene=F1NGF7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23138", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23138", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23138:SF88", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23138:SF88", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00638", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00638", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YEU1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEU1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YEU1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEU1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YKL4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKL4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YKL4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKL4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YL73", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL73", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YL73-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL73-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YN22", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN22", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YN22-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN22-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NGF7", "url": "https://www.uniprot.org/uniprotkb/F1NGF7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NGF7-1", "url": "https://www.uniprot.org/uniprotkb/F1NGF7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRNQEISACVGNVSYKDVRQCAGFDAAAGSRCFGKIKPGLPKGRDPQAAPPAAGLQAQTMHSTLNPAEEHCTERSVLAQPRFVFGKKDRPLKRPAEDPVCKAENDFICSSKKRARSSSFAFQKSISESNRDTTLAEKRGRSSSFTILPRFPPSQPAKNNNIFMTSAPLRRNIDIKSTKEGSLSESQLRNVIRPAILQPPQALTCPENPVVSLVTKKQAHIQLSENNCYSSPENPANSKTAVKSSITENISSSKTARSQLLEDRSVLSSSNSDFVFGENMVERVVSPEKHSMSCNEADSYKREIASLYIESFHVTKTALLKNATPTEAAAAHISKPGEKILLDKVEVITGEEEEHNVLQINCKLFVFNKLSLTWIEKGRGSLRLNDTSSNKCGMLQSRLIMRNQGSLRLILNTRLWGQMVIKRANSKSLCFTATDQEDHSVQVFLIQARSKDAGYLYAAIHHRLVALRSCAEQESDANQIDTESETAFQLLNCDSDEDDEKITQVSSSGSEICDTNIRMASSKQILKYECQVFMSVKPFSLSFCLLFVFKQFLSAVLTIPFKCFLDDFYHSLLISSIILRAMRF", "length": 583, "header": "tr|A0A8V0YN22-1|A0A8V0YN22_CHICK Isoform 1 of Ran-binding protein 3-like OS=Gallus gallus OX=9031 GN=RANBP3L PE=4 SV=1 CANONICAL=A0A8V0YN22-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YEU1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN22/entry#A0A8V0YEU1-1", "sequence": { "sequence": "MRNQEISACVGNVSYKDVRQCAGFDAAAGSRCFGKIKPGLPKGRDPQAAPPAAGLQAQTMHSTLNPAEEHCTERSVLAQPRFVFGKKDRPLKRPAEDPVCKAENDFICSSKKRARSSSFAFQKSISESNRDTTLAEKRGRSSSFTILPRFPPSQPAKNNNIFMTSAPLRRNIDIKSTKEGSLSESQLRNVIRPAILQPPQALTCPENPVVSLVTKKQAHIQLSENNCYSSPENPANSKTAVKSSITENISSSKTARSQLLEDRSVLSSSNSDFVFGENMVERVVSPEKHSMSCNEADSYKREIASLYIESFHVTKTALLKNATPTEAAAAHISKPGEKILLDKVEVITGEEEEHNVLQINCKLFVFNKLSLTWIEKGRGSLRLNDTSSNKCGMLQSRLIMRNQGSLRLILNTRLWGQMVIKRANSKSLCFTATDQEDHSVQVFLIQARSKDAGYLYAAIHHRLVALRSCAEQESDANQIDTESETAFQLLNCDSDEDDEKITQVSSSGSDLSARPLIPPGSQQHLSVFVSLANVLGMHSSPASLHPDHHQC", "length": 551, "header": "tr|A0A8V0YEU1-1|A0A8V0YN22_CHICK Computationally mapped isoform of Ran-binding protein 3-like OS=Gallus gallus OX=9031 GN=RANBP3L PE=4 SV=1 CANONICAL=A0A8V0YN22-1" }, "locus": { "chromosome": "Z", "start_pos": 11617820, "end_pos": 11585520, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032645.1", "url": "https://www.ensembl.org/id/ENSGALT00010032645.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019345.1", "url": "https://www.ensembl.org/id/ENSGALP00010019345.1" } ] } }, { "isoform_ac": "A0A8V0YKL4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN22/entry#A0A8V0YKL4-1", "sequence": { "sequence": "MRNQEISACVGNVSYKDVRQCAGFDAAAGSRCFGKIKPGLPKGRDPQAAPPAAGLQAQTMHSTLNPAEEHCTERSVLAQPRFVFGKKDRPLKRPAEDPVCKAENDTTLAEKRGRSSSFTILPRFPPSQPAKNNNIFMTSAPLRRNIDIKSTKEGSLSESQLRNVIRPAILQPPQALTCPENPVVSLVTKKQAHIQLSENNCYSSPENPANSKTAVKSSITENISSSKTARSQLLEDRSVLSSSNSDFVFGENMVERVVSPEKHSMSCNEADSYKREIASLYIESFHVTKTALLKNATPTEAAAAHISKPGEKILLDKVEVITGEEEEHNVLQINCKLFVFNKLSLTWIEKGRGSLRLNDTSSNKCGMLQSRLIMRNQGSLRLILNTRLWGQMVIKRANSKSLCFTATDQEDHSVQVFLIQARSKDAGYLYAAIHHRLVALRSCAEQESDANQIDTESETAFQLLNCDSDEDDEKITQVSSSGSDHSRWKRRQPVVCS", "length": 497, "header": "tr|A0A8V0YKL4-1|A0A8V0YN22_CHICK Computationally mapped isoform of Ran-binding protein 3-like OS=Gallus gallus OX=9031 GN=RANBP3L PE=4 SV=1 CANONICAL=A0A8V0YN22-1" }, "locus": { "chromosome": "Z", "start_pos": 11617820, "end_pos": 11580116, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032661.1", "url": "https://www.ensembl.org/id/ENSGALT00010032661.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019355.1", "url": "https://www.ensembl.org/id/ENSGALP00010019355.1" } ] } }, { "isoform_ac": "A0A8V0YL73-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN22/entry#A0A8V0YL73-1", "sequence": { "sequence": "MRNQEISACVGNVSYKDVRQCAGFDAAAGSRCFGKIKPGLPKGRDPQAAPPAAGLQAQTMHSTLNPAEEHCTERSVLAQPRFVFGKKDRPLKRPAEDPVCKAENDFICSSKKRARSSSFAFQKSISESNRDTTLAEKRGRSSSFTILPRFPPSQPAKNNNIFMTSAPLRRNIDIKSTKEGSLSESQLRNVIRPAILQPPQALTCPENPVVSLVTKKQAHIQLSENNCYSSPENPANSKTAVKSSITENISSSKTARSQLLEDRSVLSSSNSDFVFGENMVERVVSPEKHSMSCNEADSYKREIASLYIESFHVTKTALLKNATPTEAAAAHISKPGEKILLDKVEVITGEEEEHNVLQINCKLFVFNKLSLTWIEKGRGSLRLNDTSSNKCGMLQSRLIMRNQGSLRLILNTRLWGQMVIKRANSKSLCFTATDQEDHSVQVFLIQARSKDAGYLYAAIHHRLVALRSCAEQESDANQIDTESETAFQLLNCDSDEDDEKITQVSSSGSGSYGEP", "length": 515, "header": "tr|A0A8V0YL73-1|A0A8V0YN22_CHICK Computationally mapped isoform of Ran-binding protein 3-like OS=Gallus gallus OX=9031 GN=RANBP3L PE=4 SV=1 CANONICAL=A0A8V0YN22-1" }, "locus": { "chromosome": "Z", "start_pos": 11617820, "end_pos": 11586123, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032640.1", "url": "https://www.ensembl.org/id/ENSGALT00010032640.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019342.1", "url": "https://www.ensembl.org/id/ENSGALP00010019342.1" } ] } }, { "isoform_ac": "A0A8V0YN22-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN22/entry#A0A8V0YN22-1", "sequence": { "sequence": "MRNQEISACVGNVSYKDVRQCAGFDAAAGSRCFGKIKPGLPKGRDPQAAPPAAGLQAQTMHSTLNPAEEHCTERSVLAQPRFVFGKKDRPLKRPAEDPVCKAENDFICSSKKRARSSSFAFQKSISESNRDTTLAEKRGRSSSFTILPRFPPSQPAKNNNIFMTSAPLRRNIDIKSTKEGSLSESQLRNVIRPAILQPPQALTCPENPVVSLVTKKQAHIQLSENNCYSSPENPANSKTAVKSSITENISSSKTARSQLLEDRSVLSSSNSDFVFGENMVERVVSPEKHSMSCNEADSYKREIASLYIESFHVTKTALLKNATPTEAAAAHISKPGEKILLDKVEVITGEEEEHNVLQINCKLFVFNKLSLTWIEKGRGSLRLNDTSSNKCGMLQSRLIMRNQGSLRLILNTRLWGQMVIKRANSKSLCFTATDQEDHSVQVFLIQARSKDAGYLYAAIHHRLVALRSCAEQESDANQIDTESETAFQLLNCDSDEDDEKITQVSSSGSEICDTNIRMASSKQILKYECQVFMSVKPFSLSFCLLFVFKQFLSAVLTIPFKCFLDDFYHSLLISSIILRAMRF", "length": 583, "header": "tr|A0A8V0YN22-1|A0A8V0YN22_CHICK Isoform 1 of Ran-binding protein 3-like OS=Gallus gallus OX=9031 GN=RANBP3L PE=4 SV=1 CANONICAL=A0A8V0YN22-1" }, "locus": { "chromosome": "Z", "start_pos": 11617820, "end_pos": 11584103, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032649.1", "url": "https://www.ensembl.org/id/ENSGALT00010032649.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019348.1", "url": "https://www.ensembl.org/id/ENSGALP00010019348.1" } ] } }, { "isoform_ac": "F1NGF7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN22/entry#F1NGF7-1", "sequence": { "sequence": "MRNQEISACVGNVSYKDVRQCAGFDAAAGSRCFGKIKPGLPKGRDPQAAPPAAGLQAQTMHSTLNPAEEHCTERSVLAQPRFVFGKKDRPLKRPAEDPVCKAENDFICSSKKRARSSSFAFQKSISESNRDTTLAEKRGRSSSFTILPRFPPSQPAKNNNIFMTSAPLRRNIDIKSTKEGSLSESQLRNVIRPAILQPPQALTCPENPVVSLVTKKQAHIQLSENNCYSSPENPANSKTAVKSSITENISSSKTARSQLLEDRSVLSSSNSDFVFGENMVERVVSPEKHSMSCNEADSYKREIASLYIESFHVTKTALLKNATPTEAAAAHISKPGEKILLDKVEVITGEEEEHNVLQINCKLFVFNKLSLTWIEKGRGSLRLNDTSSNKCGMLQSRLIMRNQGSLRLILNTRLWGQMVIKRANSKSLCFTATDQEDHSVQVFLIQARSKDAGYLYAAIHHRLVALRSCAEQESDANQIDTESETAFQLLNCDSDEDDEKITQVSSSGSDHSRWKRRQPVVCS", "length": 523, "header": "tr|F1NGF7-1|F1NGF7_CHICK Computationally mapped isoform of Ran-binding protein 3-like OS=Gallus gallus OX=9031 GN=RANBP3L PE=4 SV=3 CANONICAL=A0A8V0YN22-1" }, "locus": { "chromosome": "Z", "start_pos": 11617820, "end_pos": 11580116, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032653.1", "url": "https://www.ensembl.org/id/ENSGALT00010032653.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019351.1", "url": "https://www.ensembl.org/id/ENSGALP00010019351.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:770629", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:770629", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I5YCF1-1", "protein_name": "Ran-binding protein 3-like", "gene_name": "Ranbp3l", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSTTPRKDDSHLFTSVRPCQLKVQEEQQPQEKYVIAQPIFVFEKGEHNFKRPAEDSLDEAAELEFTGFLRKRVRSSSVTLRTTDSQSLGDLNCSPNNRVPVELDKRPSSLMTCICNLLLVAALSQARLRSSSFTDVPTFPPSRPVRKNNVFMTSRLLQRNDDMNNVGQGPPVRPSDHVLRPAVLQPSRTQSCQKGGTTLGPGASKTCETKENTEHKISEADSSLLSENLSNARSSVQMSTDPCISEAPSGGHPKEDECSFTSCSSDFVFGENMVERVLGTQKLTQHPLQNLSYAKEKSFKSLLKFPNVASNSEPIKNISLIESAAAFSSKPSQKCLLEKIDVITGEETEHNVLKINCKIFVFNKATQSWSERGQGVLRLNDTAGSECGTLQSRLIMRNQGSLRLVLNSRLWAQMRTQRASHKSLRITATDLEDDRIKIFLIQASAKDIGFLYAAIHHRLVALRSLGQQGDGGPAGKQADTVLPQVSGGSCDEDEDDITQVTKTGPDPSRWNHRQSIVCL", "length": 519 }, "evidence": [ { "id": "A0A8V0YN22", "url": "https://omabrowser.org/oma/group/A0A8V0YN22/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6PDH4-1", "protein_name": "Ran-binding protein 3-like", "gene_name": "Ranbp3l", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSTTQRKDDSHLFTSSCTRQLQVQEDRQQQEKYVIAQPIFVFEKGEHNFKRPAEDSLEETAEPEFTGFLRKRVRSSSVTLHTTDPQSQGVATLSQTRLRSSSFTDVPTFPPCRPVRKNNVFMTSRLLQRSDDMNNVEQGPPMRSSEQVLRPAVLQPSQTQSCQKAGTTFGPGALKSYKTKEKAEHEISEVGSSSSLLSENLPNARSSIQLSTDPCISEAPSGCQPKEDKCSFTSCSSDFVFGENMVERVLGTQKLTQPPLQNLSYAKEKTFKSVLKFPNAVSNSDSIENISLVESAAAFSSKPSQKCLLEKIDVITGEETEHNVLKINCKIFVFNKATESWSERGQGILRLNDTAGRECGTLQSRLIMRNQGSLRLVLNSRLWAQMKIQRASQKNLRITATDLEDDGIKIFLIQASAKDTGFLYAAIHHRLVALRSLAKQGDGGPAESQSDTALPQLNGESCDEDEDEIAQVTKNGSDPSRWSHRQSIVCS", "length": 491 }, "evidence": [ { "id": "A0A8V0YN22", "url": "https://omabrowser.org/oma/group/A0A8V0YN22/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q86VV4-1", "protein_name": "Ran-binding protein 3-like", "gene_name": "RANBP3L", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTTIPRKGSSHLPGSLHTCKLKLQEDRRQQEKSVIAQPIFVFEKGEQTFKRPAEDTLYEAAEPECNGFPTKRVRSSSFTFHITDSQSQGVRKNNVFMTSALVQSSVDIKSAEQGPVKHSKHVIRPAILQLPQARSCAKVRKTFGHKALESCKTKEKTNNKISEGNSYLLSENLSRARISVQLSTNQDFLGATSVGCQPNEDKCSFKSCSSNFVFGENMVERVLGTQKLTQPQLENDSYAKEKPFKSIPKFPVNFLSSRTDSIKNTSLIESAAAFSSQPSRKCLLEKIDVITGEETEHNVLKINCKLFIFNKTTQSWIERGRGTLRLNDTASTDCGTLQSRLIMRNQGSLRLILNSKLWAQMKIQRANHKNVRITATDLEDYSIKIFLIQASAQDTAYLYAAIHHRLVALQSFNKQRDVNQAESLSETAQQLNCESCDENEDDFIQVTKNGSDPSSWTHRQSVACS", "length": 465 }, "evidence": [ { "id": "A0A8V0YN22", "url": "https://omabrowser.org/oma/group/A0A8V0YN22/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YN22", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN22" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YN22", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN22" } ], "pmid": "" }, { "name": "nuclear pore", "id": "GO:0005643", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005643", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YN22", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN22" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "SMAD binding", "id": "GO:0046332", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046332", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YN22", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN22" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "mesenchymal cell differentiation involved in bone development", "id": "GO:1901706", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901706", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YN22", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN22" } ], "pmid": "" }, { "name": "negative regulation of osteoblast differentiation", "id": "GO:0045668", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045668", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YN22", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN22" } ], "pmid": "" }, { "name": "protein export from nucleus", "id": "GO:0006611", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006611", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YN22", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN22" } ], "pmid": "" }, { "name": "positive regulation of myoblast differentiation", "id": "GO:0045663", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045663", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YN22", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN22" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 12, "end_pos": 14, "annotation": "n_glycosylation_sequon" }, { "start_pos": 248, "end_pos": 250, "annotation": "n_glycosylation_sequon" }, { "start_pos": 321, "end_pos": 323, "annotation": "n_glycosylation_sequon" }, { "start_pos": 384, "end_pos": 386, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YN22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN22" }, { "id": "PS50196", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50196" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RanBD1", "eco_id": "ECO_0000259", "start_pos": 340, "end_pos": 451, "start_aa": "Leu", "end_aa": "Asp", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 12, "end_pos": 14 }, { "start_pos": 248, "end_pos": 250 }, { "start_pos": 321, "end_pos": 323 }, { "start_pos": 384, "end_pos": 386 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YMX6-1", "uniprot_ac": "A0A8V0YMX6", "uniprot_id": "A0A8V0YMX6_CHICK", "mass": { "chemical_mass": 134893.0, "monoisotopic_mass": 134893.0 }, "refseq": { "ac": "XP_015145869", "name": "potassium channel subfamily T member 2 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015145869" }, "gene_names": [ { "name": "KCNT2", "type": "recommended", "evidence": [ { "id": "A0A8V0YMX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMX6" } ] }, { "name": "KCNT2", "type": "synonym", "evidence": [ { "id": "XP_015145869", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015145869" } ] } ], "protein_names": [ { "name": "Potassium sodium-activated channel subfamily T member 2", "type": "synonym", "evidence": [ { "id": "A0A8V0YMX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMX6/entry#names_and_taxonomy" } ] }, { "name": "potassium channel subfamily T member 2 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015145869", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015145869" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052539.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015145869.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015145869", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015145869" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMX6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMX6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "KCNT2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMX6", "locus": { "chromosome": "8", "start_pos": 2811071, "end_pos": 2702523, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012498", "url": "https://www.ensembl.org/id/ENSGALG00010012498" } ] } } ], "crossref": [ { "id": "A0A8V0YMX6", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YMX6", "database": "AlphaFoldDB", "categories": [] }, { "id": "429058", "url": "https://www.ncbi.nlm.nih.gov/gene/429058", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003148", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003148", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003929", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003929", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013099", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013099", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036291", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036291", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047871", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047871", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:429058", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:429058", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "SDVHPTY", "url": "https://omabrowser.org/oma/group/SDVHPTY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y9T1", "url": "https://www.orthodb.org/?gene=A0A8V0Y9T1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YF02", "url": "https://www.orthodb.org/?gene=A0A8V0YF02", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YI44", "url": "https://www.orthodb.org/?gene=A0A8V0YI44", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YI58", "url": "https://www.orthodb.org/?gene=A0A8V0YI58", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YMW2", "url": "https://www.orthodb.org/?gene=A0A8V0YMW2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YMX6", "url": "https://www.orthodb.org/?gene=A0A8V0YMX6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YMY1", "url": "https://www.orthodb.org/?gene=A0A8V0YMY1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10027", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10027", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10027:SF9", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10027:SF9", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03493", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03493", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07885", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07885", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF22614", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22614", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015145869", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015145869", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "29463", "url": "https://www.rhea-db.org/rhea/29463", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0Y9T1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9T1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y9T1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9T1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YF02", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF02", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YF02-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF02-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YI44", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI44", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YI44-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI44-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YI58", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI58", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YI58-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI58-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YMW2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMW2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YMW2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMW2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YMX6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMX6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YMX6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMX6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YMY1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMY1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YMY1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMY1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVDLDSEVPPLPPRYRFRDLLLGDQGWQSDDRVQVEFYMNENTFKERLKLFFIKNQRSSLRIRLFNFSLKLLSCFLYIIRVLLDDPTQGHGCKELNRDCYNQNYTPGTIDWSPIIWVNRSLPLWGLQVSVALISLFETLLLSYLSYKGNIWEQILRIPFLLEIINAVPFIITIFWPVLRNLFIPVFLNCWLAKHALENMINDLHRAIQRTQSAMFNQVLILISTLLCLIFTCICGIQHLERAGNKLTLFDSLYFCIVTFSTVGFGDVTPKIWPSKLLVVIMICVALVVLPIQFEQLAYLWMERQKSGGNYSRHRAQTEKHVVLCVSSLKIDLLMDFLNEFYAHPRLQDYYVVILCPTEMDAQVRRVLQIPMWSQRVIYLQGSALKDQDLLRAKMDDAEACFILSSRCEVDRTAADHQTILRAWAVKDFAPNCPLYVQILKPENKFHIKFADHVVCEEEFKYAMLALNCICPATSTLITLLVHTSRGQTAPWEAFRQLTGTKQTLNRESQQSSEQWQKMYGRCSGNEVFHINLEESTFFAEYEGKSFTYASFHAHKKFGVCLIGVRKEDNKNILLNPGPRYIMSSTDICFYINITKEENSAFKKQEKHRKRHESKLSYHGASRLPVHSIIASMGTVAIDLQDTGCRTSSGPTLALPSEEGKEGRRPSIAPVLEVADSSSLQACDLLSDQSEDETTPSDDEVSAGLEYAKGYPPYSPYIGSSPTFCHLLHEKVPFCCLRLDKGCQHNYYEDAKAYGFKNKLIIVAAETAGNGLYNFIVPLRAYYRPKKELNPIVLLLDNPPDMHFLDAICWFPMVYYMVGSIDNLDDLLRCGVTFAANMVVVDKESTMSAEEDYMADAKTIVNVQTLFRLFSSLSIITELTHPANMRFMQFRAKDCYSLALSKLEKKEREKGSNLAFMFRLPFAAGRVFSISMLDTLLYQSFVKDYMISITRLLLGLDTTPGSGFLCSMKITEEDLWIRTYARLYQKLCSSTGDIPIGVYRTESQKLTTSESQISISVEEWEDTKDTREQVNYRSNHRNSTSSDQSDHPLLRRKSMQWARRLSRRVPRHSGKTAERISQQRMNLYRRSERQELAELVKNRMKHLGLSPAGYDEMNDHQNNLSYILINPSPDTRLELNDIVYLIRPDPLAYVPNTASSRKDSFCNTVGQDTREETQL", "length": 1174, "header": "tr|A0A8V0YMX6-1|A0A8V0YMX6_CHICK Isoform 1 of Potassium sodium-activated channel subfamily T member 2 OS=Gallus gallus OX=9031 GN=KCNT2 PE=4 SV=1 CANONICAL=A0A8V0YMX6-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Y9T1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMX6/entry#A0A8V0Y9T1-1", "sequence": { "sequence": "MVDLDSEVPPLPPRYRFRDLLLGDQGWQSDDRVQVEFYMNENTFKERLKLFFIKNQRSSLRIRLFNFSLKLLSCFLYIIRVLLDDPTQGHGCKELNRDCYNQNYTPGTIDWSPIIWVNRSLPLWGLQVSVALISLFETLLLSYLSYKGNIWEQILRIPFLLEIINAVPFIITIFWPVLRNLFIPVFLNCWLAKHALENMINDLHRAIQRTQSAMFNQVLILISTLLCLIFTCICGIQHLERAGNKLTLFDSLYFCIVTFSTVGFGDVTPKIWPSKLLVVIMICVALVVLPIQFEQLAYLWMERQKSGGNYSRHRAQTEKHVVLCVSSLKIDLLMDFLNEFYAHPRLQDYYVVILCPTEMDAQVRRVLQIPMWSQRVIYLQGSALKDQDLLRAKMDDAEACFILSSRCEVDRTAADHQTILRAWAVKDFAPNCPLYVQILKPENKFHIKFADHVVCEEEFKYAMLALNCICPATSTLITLLVHTSRGQTAPWEAFRQLTGTKQTLNRESQQSSEQWQKMYGRCSGNEVFHINLEESTFFAEYEGKSFTYASFHAHKKFGVCLIGVRKEDNKNILLNPGPRYIMSSTDICFYINITKEENSAFKKQEKHRKRHESKLSYHGASRLPVHSIIASMGTVAIDLQDTGCRTSSGPTLALPSEEGKEGRRPSIAPVLEVADSSSLQACDLLSDQSEDETTPSDDEVSAGLEYAKGYPPYSPYIGSSPTFCHLLHEKVPFCCLRLDKGCQHNYYEDAKAYGFKNKLIIVAAETAGNGLYNFIVPLRAYYRPKKELNPIVLLLDNPPDMHFLDAICWFPMVYYMVGSIDNLDDLLRCGVTFAANMVVVDKESTMSAEEDYMADAKTIVNVQTLFRLFSSLSIITELTHPANMRFMQFRAKDCYSLALSKLEKMKITEEDLWIRTYARLYQKLCSSTGDIPIGVYRTESQKLTTSESQISISVEEWEDTKDTREQVNYRSNHRNSTSSDQSDHPLLRRKSMQWARRLSRRVPRHSGKTAERISQQRMNLYRRSERQELAELVKNRMKHLGLSPAGYDEMNDHQNNLSYILINPSPDTRLELNDIVYLIRPDPLAYVPNTASSRKDSFCNTVGQDTREETQL", "length": 1112, "header": "tr|A0A8V0Y9T1-1|A0A8V0Y9T1_CHICK Computationally mapped isoform of Potassium sodium-activated channel subfamily T member 2 OS=Gallus gallus OX=9031 GN=KCNT2 PE=4 SV=1 CANONICAL=A0A8V0YMX6-1" }, "locus": { "chromosome": "8", "start_pos": 2809802, "end_pos": 2702586, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030091.1", "url": "https://www.ensembl.org/id/ENSGALT00010030091.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017482.1", "url": "https://www.ensembl.org/id/ENSGALP00010017482.1" } ] } }, { "isoform_ac": "A0A8V0YF02-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMX6/entry#A0A8V0YF02-1", "sequence": { "sequence": "MVDLDSEVPPLPPRYRFRDLLLGDQGWQSDDRVQVEFYMNENTFKERLKLFFIKNQRSSLRIRLFNFSLKLLSCFLYIIRVLLDDPTQGHGCKELNRDCYNQNYTPGTIDWSPIIWVNRSLPLWGLQVSVALISLFETLLLSYLSYKGNIWEQILRIPFLLEIINAVPFIITIFWPVLRNLFIPVFLNCWLAKHALENMINDLHRAIQRTQSAMFNQVLILISTLLCLIFTCICGIQHLERAGNKLTLFDSLYFCIVTFSTVGFGDVTPKIWPSKLLVVIMICVALVVLPIQFEQLAYLWMERQKSGGNYSRHRAQTEKHVVLCVSSLKIDLLMDFLNEFYAHPRLQDYYVVILCPTEMDAQVRRVLQIPMWSQRVIYLQGSALKDQDLLRAKMDDAEACFILSSRCEVDRTAADHQTILRAWAVKDFAPNCPLYVQILKPENKFHIKFADHVVCEEEFKYAMLALNCICPATSTLITLLVHTSRGQTAPWEAFRQLTGTKQTLNRESQQSSEQWQKMYGRCSGNEVFHINLEESTFFAEYEGKSFTYASFHAHKKFGVCLIGVRKEDNKNILLNPGPRYIMSSTDICFYINITKEENSAFKKQEKHRKRHESKLSYHGASRLPVHSIIASMGTVAIDLQDTGCRTSSGPTLALPSEEGKEGRRPSIAPVLEVADSSSLQACDLLSDQSEDETTPSDDEVSAGLEYAKGYPPYSPYIGSSPTFCHLLHEKVPFCCLRLDKGCQHNYYEDAKAYGFKNKLIIVAAETAGNGLYNFIVPLRAYYRPKKELNPIVLLLDNPPDMHFLDAICWFPMVYYMVGSIDNLDDLLRCGVTFAANMVVVDKESTMSAEEDYMADAKTIVNVQTLFRLFSSLSIITELTHPANMRFMQFRAKDCYSLALSKLEKSQISISVEEWEDTKDTREQVNYRSNHRNSTSSDQSDHPLLRRKSMQWARRLSRRVPRHSGKTAERISQQRMNLYRRSERQELAELVKNRMKHLGLSPAGYDEMNDHQNNLSYILINPSPDTRLELNDIVYLIRPDPLAYVPNTASSRKDSFCNTVGQDTREETQL", "length": 1069, "header": "tr|A0A8V0YF02-1|A0A8V0YMX6_CHICK Computationally mapped isoform of Potassium sodium-activated channel subfamily T member 2 OS=Gallus gallus OX=9031 GN=KCNT2 PE=4 SV=1 CANONICAL=A0A8V0YMX6-1" }, "locus": { "chromosome": "8", "start_pos": 2809802, "end_pos": 2702586, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030108.1", "url": "https://www.ensembl.org/id/ENSGALT00010030108.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017491.1", "url": "https://www.ensembl.org/id/ENSGALP00010017491.1" } ] } }, { "isoform_ac": "A0A8V0YI44-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMX6/entry#A0A8V0YI44-1", "sequence": { "sequence": "MLIQLFHKHIPLIIACRVQVEFYMNENTFKERLKLFFIKNQRSSLRIRLFNFSLKLLSCFLYIIRVLLDDPTQGHGCKELNRDCYNQNYTPGTIDWSPIIWVNRSLPLWGLQVSVALISLFETLLLSYLSYKGNIWEQILRIPFLLEIINAVPFIITIFWPVLRNLFIPVFLNCWLAKHALENMINDLHRAIQRTQSAMFNQVLILISTLLCLIFTCICGIQHLERAGNKLTLFDSLYFCIVTFSTVGFGDVTPKIWPSKLLVVIMICVALVVLPIQFEQLAYLWMERQKSGGNYSRHRAQTEKHVVLCVSSLKIDLLMDFLNEFYAHPRLQDYYVVILCPTEMDAQVRRVLQIPMWSQRVIYLQGSALKDQDLLRAKMDDAEACFILSSRCEVDRTAADHQTILRAWAVKDFAPNCPLYVQILKPENKFHIKFADHVVCEEEFKYAMLALNCICPATSTLITLLVHTSRGQTAPWEAFRQLTGTKQTLNRESQQSSEQWQKMYGRCSGNEVFHINLEESTFFAEYEGKSFTYASFHAHKKFGVCLIGVRKEDNKNILLNPGPRYIMSSTDICFYINITKEENSAFKKQEKHRKRHESKLSYHGASRLPVHSIIASMGTVAIDLQDTGCRTSSGPTLALPSEEGKEGRRPSIAPVLEVADSSSLQACDLLSDQSEDETTPSDDEVSAGLEYAKGYPPYSPYIGSSPTFCHLLHEKVPFCCLRLDKGCQHNYYEDAKAYGFKNKLIIVAAETAGNGLYNFIVPLRAYYRPKKELNPIVLLLDNPLDDLLRCGVTFAANMVVVDKESTMSAEEDYMADAKTIVNVQTLFRLFSSLSIITELTHPANMRFMQFRAKDCYSLALSKLEKKEREKGSNLAFMFRLPFAAGRVFSISMLDTLLYQSFVKDYMISITRLLLGLDTTPGSGFLCSMKITEEDLWIRTYARLYQKLCSSTGDIPIGVYRTESQKLTTSESQISISVEEWEDTKDTREQVNYRSNHRNSTSSDQSDHPLLRRKSMQWARRLSRRVPRHSGKTAERISQQRMNLYRRSERQELAELVKNRMKHLGLSPAGYDEMNDHQNNLSYILINPSPDTRLELNDIVYLIRPDPLAYVPNTASSRKDSFCNTVGQDTREETQL", "length": 1135, "header": "tr|A0A8V0YI44-1|A0A8V0YMX6_CHICK Computationally mapped isoform of Potassium sodium-activated channel subfamily T member 2 OS=Gallus gallus OX=9031 GN=KCNT2 PE=4 SV=1 CANONICAL=A0A8V0YMX6-1" }, "locus": { "chromosome": "8", "start_pos": 2809802, "end_pos": 2712356, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030068.1", "url": "https://www.ensembl.org/id/ENSGALT00010030068.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017470.1", "url": "https://www.ensembl.org/id/ENSGALP00010017470.1" } ] } }, { "isoform_ac": "A0A8V0YI58-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMX6/entry#A0A8V0YI58-1", "sequence": { "sequence": "MVDLDSEVPPLPPRYRFRDLLLGDQGWQSDDRVQVEFYMNENTFKERLKLFFIKNQRSSLRIRLFNFSLKLLSCFLYIIRVLLDDPTQGHGCKELNRDCYNQNYTPGTIDWSPIIWVNRSLPLWGLQVSVALISLFETLLLSYLSYKGNIWEQILRIPFLLEIINAVPFIITIFWPVLRNLFIPVFLNCWLAKHALENMINDLHRAIQRTQSAMFNQVLILISTLLCLIFTCICGIQHLERAGNKLTLFDSLYFCIVTFSTVGFGDVTPKIWPSKLLVVIMICVALVVLPIQDYYVVILCPTEMDAQVRRVLQIPMWSQRVIYLQGSALKDQDLLRAKMDDAEACFILSSRCEVDRTAADHQTILRAWAVKDFAPNCPLYVQILKPENKFHIKFADHVVCEEEFKYAMLALNCICPATSTLITLLVHTSRGQTAPWEAFRQLTGTKQTLNRESQQSSEQWQKMYGRCSGNEVFHINLEESTFFAEYEGKSFTYASFHAHKKFGVCLIGVRKEDNKNILLNPGPRYIMSSTDICFYINITKEENSAFKKQEKHRKRHESKLSYHGASRLPVHSIIASMGTVAIDLQDTGCRTSSGPTLALPSEEGKEGRRPSIAPVLEVADSSSLQACDLLSDQSEDETTPSDDEVSAGLEYAKGYPPYSPYIGSSPTFCHLLHEKVPFCCLRLDKGCQHNYYEDAKAYGFKNKLIIVAAETAGNGLYNFIVPLRAYYRPKKELNPIVLLLDNPLDDLLRCGVTFAANMVVVDKESTMSAEEDYMADAKTIVNVQTLFRLFSSLSIITELTHPANMRFMQFRAKDCYSLALSKLEKKEREKGSNLAFMFRLPFAAGRVFSISMLDTLLYQSFVKDYMISITRLLLGLDTTPGSGFLCSMKITEEDLWIRTYARLYQKLCSSTGDIPIGVYRTESQKLTTSESQISISVEEWEDTKDTREQVNYRSNHRNSTSSDQSDHPLLRRKSMQWARRLSRRVPRHSGKTAERISQQRMNLYRRSERQELAELVKNRMKHLGLSPAGYDEMNDHQNNLSYILINPSPDTRLELNDIVYLIRPDPLAYVPNTASSRKDSFCNTVGQDTREETQL", "length": 1095, "header": "tr|A0A8V0YI58-1|A0A8V0YMX6_CHICK Computationally mapped isoform of Potassium sodium-activated channel subfamily T member 2 OS=Gallus gallus OX=9031 GN=KCNT2 PE=4 SV=1 CANONICAL=A0A8V0YMX6-1" }, "locus": { "chromosome": "8", "start_pos": 2809802, "end_pos": 2702586, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030099.1", "url": "https://www.ensembl.org/id/ENSGALT00010030099.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017485.1", "url": "https://www.ensembl.org/id/ENSGALP00010017485.1" } ] } }, { "isoform_ac": "A0A8V0YMW2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMX6/entry#A0A8V0YMW2-1", "sequence": { "sequence": "SMKSSLQRFEFYMNENTFKERLKLFFIKNQRSSLRIRLFNFSLKLLSCFLYIIRVLLDDPTQGHGWSPIIWVNRSLPLWGLQVINAYHCNMLFIFFPFSLKGNIWEQILRIPFLLEIINAVPFIITIFWPVLRNLFIPVFLNCWLAKHALENMINDLHRAIQRTQSAMFNQVLILISTLLCLIFTCICGIQHLERAGNKLTLFDSLYFCIVTFSTVGFGDVTPKIWPSKLLVVIMICVALVVLPIQFEQLAYLWMERQKSGGNYSRHRAQTEKHVVLCVSSLKIDLLMDFLNEFYAHPRLQDYYVVILCPTEMDAQVRRVLQIPMWSQRVIYLQGSALKDQDLLRAKMDDAEACFILSSRCEVDRTAADHQTILRAWAVKDFAPNCPLYVQILKPENKFHIKFADHVVCEEEFKYAMLALNCICPATSTLITLLVHTSRGQESQQSSEQWQKMYGRCSGNEVFHINLEESTFFAEYEGKSFTYASFHAHKKFGVCLIGVRKEDNKNILLNPGPRYIMSSTDICFYINITKEENSAFKKQEKHRKRHESKLSYHGASRLPVHSIIASMGTVAIDLQDTGCRTSSGPTLALPSEEGKEGRRPSIAPVLEVADSSSLQACDLLSDQSEDETTPSDDEVSAGLEYAKGYPPYSPYIGSSPTFCHLLHEKVPFCCLRLDKGCQHNYYEDAKAYGFKNKLIIVAAETAGNGLYNFIVPLRAYYRPKKELNPIVLLLDNPPDMHFLDAICWFPMVYYMVGSIDNLDDLLRCGVTFAANMVVVDKESTMSAEEDYMADAKTIVNVQTLFRLFSSLSIITELTHPANMRFMQFRAKDCYSLALSKLEKKEREKGSNLAFMFRLPFAAGRVFSISMLDTLLYQSFVKDYMISITRLLLGLDTTPGSGFLCSMKITEEDLWIRTYARLYQKLCSSTGDIPIGVYRTESQKLTTSESQISISVEEWEDTKDTREQVNYRSNHRNSTSSDQSDHPLLRRKSMQWARRLSRRVPRHSGKTAERISQQRMNLYRRSERQELAELVKNRMKHLGLSPAGYDEMNDHQNNLSYILINPSPDTRLELNDIVYLIRPDPLAYVPNTASSRKDSFCNTVGQDTREETQL", "length": 1109, "header": "tr|A0A8V0YMW2-1|A0A8V0YMW2_CHICK Computationally mapped isoform of Potassium sodium-activated channel subfamily T member 2 OS=Gallus gallus OX=9031 GN=KCNT2 PE=4 SV=1 CANONICAL=A0A8V0YMX6-1" }, "locus": { "chromosome": "8", "start_pos": 2809802, "end_pos": 2725329, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030041.1", "url": "https://www.ensembl.org/id/ENSGALT00010030041.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017458.1", "url": "https://www.ensembl.org/id/ENSGALP00010017458.1" } ] } }, { "isoform_ac": "A0A8V0YMX6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMX6/entry#A0A8V0YMX6-1", "sequence": { "sequence": "MVDLDSEVPPLPPRYRFRDLLLGDQGWQSDDRVQVEFYMNENTFKERLKLFFIKNQRSSLRIRLFNFSLKLLSCFLYIIRVLLDDPTQGHGCKELNRDCYNQNYTPGTIDWSPIIWVNRSLPLWGLQVSVALISLFETLLLSYLSYKGNIWEQILRIPFLLEIINAVPFIITIFWPVLRNLFIPVFLNCWLAKHALENMINDLHRAIQRTQSAMFNQVLILISTLLCLIFTCICGIQHLERAGNKLTLFDSLYFCIVTFSTVGFGDVTPKIWPSKLLVVIMICVALVVLPIQFEQLAYLWMERQKSGGNYSRHRAQTEKHVVLCVSSLKIDLLMDFLNEFYAHPRLQDYYVVILCPTEMDAQVRRVLQIPMWSQRVIYLQGSALKDQDLLRAKMDDAEACFILSSRCEVDRTAADHQTILRAWAVKDFAPNCPLYVQILKPENKFHIKFADHVVCEEEFKYAMLALNCICPATSTLITLLVHTSRGQTAPWEAFRQLTGTKQTLNRESQQSSEQWQKMYGRCSGNEVFHINLEESTFFAEYEGKSFTYASFHAHKKFGVCLIGVRKEDNKNILLNPGPRYIMSSTDICFYINITKEENSAFKKQEKHRKRHESKLSYHGASRLPVHSIIASMGTVAIDLQDTGCRTSSGPTLALPSEEGKEGRRPSIAPVLEVADSSSLQACDLLSDQSEDETTPSDDEVSAGLEYAKGYPPYSPYIGSSPTFCHLLHEKVPFCCLRLDKGCQHNYYEDAKAYGFKNKLIIVAAETAGNGLYNFIVPLRAYYRPKKELNPIVLLLDNPPDMHFLDAICWFPMVYYMVGSIDNLDDLLRCGVTFAANMVVVDKESTMSAEEDYMADAKTIVNVQTLFRLFSSLSIITELTHPANMRFMQFRAKDCYSLALSKLEKKEREKGSNLAFMFRLPFAAGRVFSISMLDTLLYQSFVKDYMISITRLLLGLDTTPGSGFLCSMKITEEDLWIRTYARLYQKLCSSTGDIPIGVYRTESQKLTTSESQISISVEEWEDTKDTREQVNYRSNHRNSTSSDQSDHPLLRRKSMQWARRLSRRVPRHSGKTAERISQQRMNLYRRSERQELAELVKNRMKHLGLSPAGYDEMNDHQNNLSYILINPSPDTRLELNDIVYLIRPDPLAYVPNTASSRKDSFCNTVGQDTREETQL", "length": 1174, "header": "tr|A0A8V0YMX6-1|A0A8V0YMX6_CHICK Isoform 1 of Potassium sodium-activated channel subfamily T member 2 OS=Gallus gallus OX=9031 GN=KCNT2 PE=4 SV=1 CANONICAL=A0A8V0YMX6-1" }, "locus": { "chromosome": "8", "start_pos": 2809802, "end_pos": 2702586, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030076.1", "url": "https://www.ensembl.org/id/ENSGALT00010030076.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017473.1", "url": "https://www.ensembl.org/id/ENSGALP00010017473.1" } ] } }, { "isoform_ac": "A0A8V0YMY1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMX6/entry#A0A8V0YMY1-1", "sequence": { "sequence": "MVDLDSEVPPLPPRYRFRDLLLGDQGWQSDDRVQVEFYMNENTFKERLKLFFIKNQRSSLRIRLFNFSLKLLSCFLYIIRVLLDDPTQGHGCKELNRDCYNQNYTPGTIDWSPIIWVNRSLPLWGLQVSVALISLFETLLLSYLSYKGNIWEQILRIPFLLEIINAVPFIITIFWPVLRNLFIPVFLNCWLAKHALENMINDLHRAIQRTQSAMFNQVLILISTLLCLIFTCICGIQHLERAGNKLTLFDSLYFCIVTFSTVGFGDVTPKIWPSKLLVVIMICVALVVLPIQFEQLAYLWMERQKSGGNYSRHRAQTEKHVVLCVSSLKIDLLMDFLNEFYAHPRLQDYYVVILCPTEMDAQVRRVLQIPMWSQRVIYLQGSALKDQDLLRAKMDDAEACFILSSRCEVDRTAADHQTILRAWAVKDFAPNCPLYVQILKPENKFHIKFADHVVCEEEFKYAMLALNCICPATSTLITLLVHTSRGQTAPWEAFRQLTGTKQTLNRESQQSSEQWQKMYGRCSGNEVFHINLEESTFFAEYEGKSFTYASFHAHKKFGVCLIGVRKEDNKNILLNPGPRYIMSSTDICFYINITKEENSAFKKQEKHRKRHESKLSYHGASRLPVHSIIASMGTVAIDLQDTGCRTSSGPTLALPSEEGKEGRRPSIAPVLEVADSSSLQACDLLSDQSEDETTPSDDEVSAGLEYAKGYPPYSPYIGSSPTFCHLLHEKVPFCCLRLDKGCQHNYYEDAKAYGFKNKLIIVAAETAGNGLYNFIVPLRAYYRPKKELNPIVLLLDNPLDDLLRCGVTFAANMVVVDKESTMSAEEDYMADAKTIVNVQTLFRLFSSLSIITELTHPANMRFMQFRAKDCYSLALSKLEKKEREKGSNLAFMFRLPFAAGRVFSISMLDTLLYQSFVKDYMISITRLLLGLDTTPGSGFLCSMKITEEDLWIRTYARLYQKLCSSTGDIPIGVYRTESQKLTTSESQISISVEEWEDTKDTREQVNYRSNHRNSTSSDQSDHPLLRRKSMQWARRLSRRVPRHSGKTAERISQQRMNLYRRSERQELAELVKNRMKHLGLSPAGYDEMNDHQNNLSYILINPSPDTRLELNDIVYLIRPDPLAYVPNTASSRKDSFCNTVGQDTREETQL", "length": 1150, "header": "tr|A0A8V0YMY1-1|A0A8V0YMY1_CHICK Computationally mapped isoform of Potassium sodium-activated channel subfamily T member 2 OS=Gallus gallus OX=9031 GN=KCNT2 PE=4 SV=1 CANONICAL=A0A8V0YMX6-1" }, "locus": { "chromosome": "8", "start_pos": 2809802, "end_pos": 2702586, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030083.1", "url": "https://www.ensembl.org/id/ENSGALT00010030083.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017478.1", "url": "https://www.ensembl.org/id/ENSGALP00010017478.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:429058", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:429058", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287AQJ0-1", "protein_name": "Potassium sodium-activated channel subfamily T member 2", "gene_name": "KCNT2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MVDLESEVPPLPPRYRFRDLLLGDQGWQNDDRVQVEFYMNENTFKERLKLFFIKNQRSSLRIRLFNFSLKLLSCLLYIIRVLLENPSQGNEWSHIFWVNRSLPLWGLQVSVALISLFETILLGYLSYKGNIWEQILRIPFILEIINAVPFIISIFWPSLRNLFVPVFLNCWLAKHALENMINDLHRAIQRTQSAMFNQVLILISTLLCLIFTCICGIQHLERIGKKLNLFDSLYFCIVTFSTVGFGDVTPETWSSKLFVVAMICVALVVLPIQFEQLAYLWMERQKSGGNYSRHRAQTEKHVVLCVSSLKIDLLMDFLNEFYAHPRLQDYYVVILCPTEMDVQVRRVLQIPMWSQRVIYLQGSALKDQDLLRAKMDDAEACFILSSRCEVDRTSSDHQTILRAWAVKDFAPNCPLYVQILKPENKFHIKFADHVVCEEEFKYAMLALNCICPATSTLITLLVHTSRGQEGQQSPEQWQKMYGRCSGNEVYHIVLEESTFFAEYEGKSFTYASFHAHKKFGVCLIGIRREDNKNILLNPGPRCIMNATDICFYINITKEENSAFKNQDQQKKNNVSRSFYHGPSRLPVHSIIASMGTVAIDLQDTSCRSASGPTLSLPTEGSKEIRRPSIAPVLEVADTSSIQTCDLLSDQSEDETTPDEEVSSNLDYAKGYPPYSPYIGSSPTFCHLLHEKVPFCCLRLDKSCQHNYYEDAKAYGFKNKLIIVAAETAGNGLYNFIVPLRAYYRPKKELNPIVLLLDNPPDMHFLDAICWFPMVYYMVGSIDNLDDLLRCGVTFAANMVVVDKESTMSAEEDYMADAKTIVNVQTLFRLFSSLSIITELTHPANMRFMQFRAKDCYSLALSKLEKKERERGSNLAFMFRLPFAAGRVFSISMLDTLLYQSFVKDYMISITRLLLGLDTTPGSGFLCSMKVTEDDLWIRTYARLYQKLCSSTGDVPIGIYRTESQKLATSEYREIASQSQISISVEEWEDTRDAKEQGHPRGNHRNSTSSDQSDHPLLRRKSLQWARRLSRKGPKHSGKTAEKITQQRLNLYRRSERQELAELVKNRMKHLGLSTVGYDEMNDHQSTLSYILINPSPDTRLELNDVVYLIRPDPLAYLPNNEPSRKNSICNTTGQDSREETQL", "length": 1142 }, "evidence": [ { "id": "A0A8V0YMX6", "url": "https://omabrowser.org/oma/group/A0A8V0YMX6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "D3Z649-1", "protein_name": "Potassium channel subfamily T member 2", "gene_name": "Kcnt2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVDLESEVPPLPPRYRFRDLLLGDQGWQNDDRVQVEFYMNENTFKERLKLFFIKNQRSSLRIRLFNFSLKLLSCLLYIIRVLLEKPSQGSEWSHIFWVNRSLPLWGLQVSVALISLFETILLGYLSYKGNIWEQILRIPFILEIINAVPFIISIFWPTLRNLFVPVFLNCWLAKHALENMINDLHRAIQRTQSAMFNQVLILISTLLCLIFTCICGIQHLERIGKKLNLFDSLYFCIVTFSTVGFGDVTPETWSSKLFVVAMICVALVVLPIQFEQLAYLWMERQKSGGNYSRHRAQTEKHVVLCVSSLKIDLLMDFLNEFYAHPRLQDYYVVILCPTEMDVQVRRVLQIPMWSQRVIYLQGSALKDQDLLRAKMDNAEACFILSSRCEVDRTSSDHQTILRAWAVKDFAPNCPLYVQILKPENKFHIKFADHVVCEEEFKYAMLALNCICPATSTLITLLVHTSRGQEGQQSPEQWQKTYGRCSGNEVYHIVLEESTFFAEYEGKSFTYASFHAHKKFGVCLVGVRREDNKNILLNPGPRYIMNASDICFYINITKEENSAFKNQDQQRKSNVSRSFYHGPSRLPVHSIIASMGTVAIDLQDTSCRATSGPTLALPSEGGKELRRPSIAPVLEVADTSSIQTCDLLSDQSEDETTPDEETSSNLEYAKGYPPYSPYIGSSPTFCHLLQEKVPFCCLRLDKSCQHNYYEDAKAYGFKNKLIIVAAETAGNGLYNFIVPLRAYYRPKKELNPIVLLLDNPPDMHFLDAICWFPMVYYMVGSIDNLDDLLRCGVTFAANMVVVDKESTMSAEEDYMADAKTIVNVQTLFRLFSSLSIITELTHPANMRFMQFRAKDCYSLALSKLEKKERERGSNLAFMFRLPFAAGRVFSISMLDTLLYQSFVKDYMISITRLLLGLDTIPGSGFLCSMKITEDDLWIRTYARLYQKLCSSTGDVPIGIYRTESQKLTTSESQISISVEEWEDTKDVKDPGHHRSLHRNSTSSDQSDHPLLRRKSMQWARRLSRKGPKHSGKTAEKITQQRLNLYRRSERQELAELVKNRMKHLGLSTVGYDEMNDHQSTLSYILINPSPDTRLELNDVVYLIRPDPLSYLPNSEPSRKNSICNAAVQDSREETQL", "length": 1135 }, "evidence": [ { "id": "A0A8V0YMX6", "url": "https://omabrowser.org/oma/group/A0A8V0YMX6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q6UVM3-1", "protein_name": "Potassium channel subfamily T member 2", "gene_name": "KCNT2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVDLESEVPPLPPRYRFRDLLLGDQGWQNDDRVQVEFYMNENTFKERLKLFFIKNQRSSLRIRLFNFSLKLLSCLLYIIRVLLENPSQGNEWSHIFWVNRSLPLWGLQVSVALISLFETILLGYLSYKGNIWEQILRIPFILEIINAVPFIISIFWPSLRNLFVPVFLNCWLAKHALENMINDLHRAIQRTQSAMFNQVLILISTLLCLIFTCICGIQHLERIGKKLNLFDSLYFCIVTFSTVGFGDVTPETWSSKLFVVAMICVALVVLPIQFEQLAYLWMERQKSGGNYSRHRAQTEKHVVLCVSSLKIDLLMDFLNEFYAHPRLQDYYVVILCPTEMDVQVRRVLQIPMWSQRVIYLQGSALKDQDLLRAKMDDAEACFILSSRCEVDRTSSDHQTILRAWAVKDFAPNCPLYVQILKPENKFHIKFADHVVCEEEFKYAMLALNCICPATSTLITLLVHTSRGQEGQQSPEQWQKMYGRCSGNEVYHIVLEESTFFAEYEGKSFTYASFHAHKKFGVCLIGVRREDNKNILLNPGPRYIMNSTDICFYINITKEENSAFKNQDQQRKSNVSRSFYHGPSRLPVHSIIASMGTVAIDLQDTSCRSASGPTLSLPTEGSKEIRRPSIAPVLEVADTSSIQTCDLLSDQSEDETTPDEEMSSNLEYAKGYPPYSPYIGSSPTFCHLLHEKVPFCCLRLDKSCQHNYYEDAKAYGFKNKLIIVAAETAGNGLYNFIVPLRAYYRPKKELNPIVLLLDNPPDMHFLDAICWFPMVYYMVGSIDNLDDLLRCGVTFAANMVVVDKESTMSAEEDYMADAKTIVNVQTLFRLFSSLSIITELTHPANMRFMQFRAKDCYSLALSKLEKKERERGSNLAFMFRLPFAAGRVFSISMLDTLLYQSFVKDYMISITRLLLGLDTTPGSGFLCSMKITADDLWIRTYARLYQKLCSSTGDVPIGIYRTESQKLTTSESQISISVEEWEDTKDSKEQGHHRSNHRNSTSSDQSDHPLLRRKSMQWARRLSRKGPKHSGKTAEKITQQRLNLYRRSERQELAELVKNRMKHLGLSTVGYDEMNDHQSTLSYILINPSPDTRIELNDVVYLIRPDPLAYLPNSEPSRRNSICNVTGQDSREETQL", "length": 1135 }, "evidence": [ { "id": "A0A8V0YMX6", "url": "https://omabrowser.org/oma/group/A0A8V0YMX6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q6UVM4-1", "protein_name": "Potassium channel subfamily T member 2", "gene_name": "Kcnt2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVDLESEVPPLPPRYRFRDLLLGDQGWQNDDRVQVEFYMNENTFKERLKLFFIKNQRSSLRIRLFNFSLKLLSCLLYIIRVLLEKPSQGNDWSHIFWVNRSLPLWGLQVSVALISLFETILLGYLSYKGNIWEQILRVPFILEIINAVPFIISIFWPTLRNLFVPVFLNCWLAKHALENMINDLHRAIQRTQSAMFNQVLILISTLLCLIFTCICGIQHLERIGKKLNLFDSLYFCIVTFSTVGFGDVTPETWSSKLFVVAMICVALVVLPIQFEQLAYLWMERQKSGGNYSRHRAQTEKHVVLCVSSLKIDLLMDFLNEFYAHPRLQDYYVVILCPTEMDVQVRRVLQIPMWSQRVIYLQGSALKDQDLLRAKMDNAEACFILSSRCEVDRTSSDHQTILRAWAVKDFAPNCPLYVQILKPENKFHIKFADHVVCEEEFKYAMLALNCICPATSTLITLLVHTSRGQCVCLCCREGQQSPEQWQKTYGRCSGNEVYHIVLEESTFFAEYEGKSFTYASFHAHKKFGVCLVGVRREDNKNILLNPGPRYIMNASDICFYINITKEENSAFKNQDQQRKSNVSRSFYHGPSRLPVHSIIASMGTVAIDLQDTSCRAASGPTLALPSEGGKELRRPSIAPVLEVADTSSIQTCDLLSDQSEDETTPDEETSSNLEYAKGYPPYSPYIGSSPTFCHLLQEKVPFCCLRLDKSCQHNYYEDAKAYGFKNKLIIVAAETAGNGLYNFIVPLRAYYRPKKELNPIVLLLDNPPDMHFLDAICWFPMVYYMVGSIDNLDDLLRCGVTFAANMVVVDKESTMSAEEDYMADAKTIVNVQTLFRLFSSLSIITELTHPANMRFMQFRAKDCYSLALSKLEKKERERGSNLAFMFRLPFAAGRVFSISMLDTLLYQSFVKDYMISITRLLLGLDTIPGSGFLCSMKITEDDLWIRTYARLYQKLCSSTGDVPIGIYRTESQKLTTSESQISISVEEWEDTKDVKDPGHHRSIHRNSTSSDQSDHPLLRRKSMQWARRLSRKGPKHSGKTAEKITQQRLNLYRRSERQELAELVKNRMKHLGLSTVGYDEMNDHQSTLSYILINPSPDTRLELNDVVYLIRPDPLSYLPNSEPSRKNSICNAAVQDSREETQL", "length": 1142 }, "evidence": [ { "id": "A0A8V0YMX6", "url": "https://omabrowser.org/oma/group/A0A8V0YMX6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMX6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMX6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "potassium channel activity", "id": "GO:0005267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005267", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMX6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMX6" } ], "pmid": "" }, { "name": "outward rectifier potassium channel activity", "id": "GO:0015271", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015271", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMX6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMX6" } ], "pmid": "" }, { "name": "intracellular sodium-activated potassium channel activity", "id": "GO:0005228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005228", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMX6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMX6" } ], "pmid": "" }, { "name": "chloride-activated potassium channel activity", "id": "GO:0070089", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070089", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMX6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMX6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "potassium ion transmembrane transport", "id": "GO:0071805", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071805", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMX6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMX6" } ], "pmid": "" }, { "name": "potassium ion export across plasma membrane", "id": "GO:0097623", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097623", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMX6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMX6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1037, "end_pos": 1039, "annotation": "n_glycosylation_sequon" }, { "start_pos": 103, "end_pos": 105, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1118, "end_pos": 1120, "annotation": "n_glycosylation_sequon" }, { "start_pos": 118, "end_pos": 120, "annotation": "n_glycosylation_sequon" }, { "start_pos": 309, "end_pos": 311, "annotation": "n_glycosylation_sequon" }, { "start_pos": 592, "end_pos": 594, "annotation": "n_glycosylation_sequon" }, { "start_pos": 66, "end_pos": 68, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "29463", "name": "", "equation": "K(+)(in) = K(+)(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "29463", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/29463" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YMX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMX6" }, { "id": "PS51201", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51201" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RCK N-terminal", "eco_id": "ECO_0000259", "start_pos": 318, "end_pos": 454, "start_aa": "Glu", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1037, "end_pos": 1039 }, { "start_pos": 103, "end_pos": 105 }, { "start_pos": 1118, "end_pos": 1120 }, { "start_pos": 118, "end_pos": 120 }, { "start_pos": 309, "end_pos": 311 }, { "start_pos": 592, "end_pos": 594 }, { "start_pos": 66, "end_pos": 68 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YNM0-1", "uniprot_ac": "A0A8V0YNM0", "uniprot_id": "A0A8V0YNM0_CHICK", "mass": { "chemical_mass": 28544.0, "monoisotopic_mass": 28544.0 }, "refseq": { "ac": "XP_046800168", "name": "regulator of G-protein signaling 4 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046800168" }, "gene_names": [ { "name": "RGS4", "type": "recommended", "evidence": [ { "id": "A0A8V0YNM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNM0" } ] }, { "name": "RGS4", "type": 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##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. 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"GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR016137", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016137", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034953", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034953", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036305", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036305", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044926", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044926", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:378901", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:378901", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YNM0", "url": "https://www.orthodb.org/?gene=A0A8V0YNM0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10845", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10845", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10845:SF184", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10845:SF184", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00615", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00615", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-416476", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-416476", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-418594", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-418594", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_046800168", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046800168", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YAE8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAE8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YAE8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAE8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YFQ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFQ8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YFQ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFQ8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YGQ9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGQ9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YGQ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGQ9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YNM0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNM0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YNM0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNM0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NHZ4", "url": "https://www.uniprot.org/uniprotkb/F1NHZ4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NHZ4-1", "url": "https://www.uniprot.org/uniprotkb/F1NHZ4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQGCLHGHHVSGFILKARQAEVAWHTQEPPRFHLAGMGSWCQEQPYLCAGRQGLVQGAKDMKHRLGVLLQKSESCDYGSSQGKKEKVSPSQRVSQEEVKKWAESLENLIHHDRGLAAFRAFLKSEYSEENIEFWVSCEDYKKTKSPAKLSTKARKIYDEFISVQATKEVNLDSCTREKTSHNMLEPTLSCFDEAQRKIFTLMEKDSYRRFLKSPYYLDLVSPPRAGCGPENCKRAHAHALDCNSNIISQCA", "length": 251, "header": "tr|A0A8V0YNM0-1|A0A8V0YNM0_CHICK Isoform 1 of Regulator of G-protein signaling 4 OS=Gallus gallus OX=9031 GN=RGS4 PE=4 SV=1 CANONICAL=A0A8V0YNM0-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YAE8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNM0/entry#A0A8V0YAE8-1", "sequence": { "sequence": 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"MQHWRGQKGNVQKGSIYSAKDMKHRLGVLLQKSESCDYGSSQGKKEKVSPSQRVSQEEVKKWAESLENLIHHDRGLAAFRAFLKSEYSEENIEFWVSCEDYKKTKSPAKLSTKARKIYDEFISVQATKEVNLDSCTREKTSHNMLEPTLSCFDEAQRKIFTLMEKDSYRRFLKSPYYLDLVSPPRAGCGPENCKRAHAHALDCNSNIISQCA", "length": 212, "header": "tr|A0A8V0YFQ8-1|A0A8V0YNM0_CHICK Computationally mapped isoform of Regulator of G-protein signaling 4 OS=Gallus gallus OX=9031 GN=RGS4 PE=4 SV=1 CANONICAL=A0A8V0YNM0-1" }, "locus": { "chromosome": "8", "start_pos": 3690606, "end_pos": 3599119, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030529.1", "url": "https://www.ensembl.org/id/ENSGALT00010030529.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017708.1", "url": "https://www.ensembl.org/id/ENSGALP00010017708.1" } ] } }, { "isoform_ac": "A0A8V0YGQ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNM0/entry#A0A8V0YGQ9-1", "sequence": { "sequence": 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"MQGCLHGHHVSGFILKARQAEVAWHTQEPPRFHLAGMGSWCQEQPYLCAGRQGLVQGAKDMKHRLGVLLQKSESCDYGSSQGKKEKVSPSQRVSQEEVKKWAESLENLIHHDRGLAAFRAFLKSEYSEENIEFWVSCEDYKKTKSPAKLSTKARKIYDEFISVQATKEVNLDSCTREKTSHNMLEPTLSCFDEAQRKIFTLMEKDSYRRFLKSPYYLDLVSPPRAGCGPENCKRAHAHALDCNSNIISQCA", "length": 251, "header": "tr|A0A8V0YNM0-1|A0A8V0YNM0_CHICK Isoform 1 of Regulator of G-protein signaling 4 OS=Gallus gallus OX=9031 GN=RGS4 PE=4 SV=1 CANONICAL=A0A8V0YNM0-1" }, "locus": { "chromosome": "8", "start_pos": 3690606, "end_pos": 3615847, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030540.1", "url": "https://www.ensembl.org/id/ENSGALT00010030540.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017715.1", "url": "https://www.ensembl.org/id/ENSGALP00010017715.1" } ] } }, { "isoform_ac": "F1NHZ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNM0/entry#F1NHZ4-1", "sequence": { "sequence": "MCKGLAALPATCLKSAKDMKHRLGVLLQKSESCDYGSSQGKKEKVSPSQRVSQEEVKKWAESLENLIHHDRGLAAFRAFLKSEYSEENIEFWVSCEDYKKTKSPAKLSTKARKIYDEFISVQATKEVNLDSCTREKTSHNMLEPTLSCFDEAQRKIFTLMEKDSYRRFLKSPYYLDLVSPPRAGCGPENCKRAHAHALDCNSNIISQCA", "length": 209, "header": "tr|F1NHZ4-1|F1NHZ4_CHICK Computationally mapped isoform of Regulator of G-protein signaling 4 OS=Gallus gallus OX=9031 GN=RGS4 PE=4 SV=1 CANONICAL=A0A8V0YNM0-1" }, "locus": { "chromosome": "8", "start_pos": 3690606, "end_pos": 3686815, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030554.1", "url": "https://www.ensembl.org/id/ENSGALT00010030554.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017727.1", "url": "https://www.ensembl.org/id/ENSGALP00010017727.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:378901", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:378901", "resource": "KEGG Pathway" }, { "id": "R-GGA-416476", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-416476", "resource": "Reactome", "description": "G alpha (q) signalling events" }, { "id": "R-GGA-418594", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-418594", "resource": "Reactome", "description": "G alpha (i) signalling events" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "negative regulation of signal transduction", "id": "GO:0009968", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009968", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNM0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNM0" } ], "pmid": "" }, { "name": "negative regulation of G protein-coupled receptor signaling pathway", "id": "GO:0045744", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045744", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNM0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNM0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNM0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNM0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNM0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNM0" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNM0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNM0" } ], "pmid": "" }, { "name": "cytoplasmic side of plasma membrane", "id": "GO:0009898", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009898", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNM0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNM0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YNM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNM0" }, { "id": "PS50132", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50132" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RGS", "eco_id": "ECO_0000259", "start_pos": 104, "end_pos": 220, "start_aa": "Ser", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YP40-1", "uniprot_ac": "A0A8V0YP40", "uniprot_id": "A0A8V0YP40_CHICK", "mass": { "chemical_mass": 293187.0, "monoisotopic_mass": 293187.0 }, "refseq": {}, "gene_names": [ { "name": "PRRC2C", "type": "recommended", "evidence": [ { "id": "A0A8V0YP40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP40" } ] } ], "protein_names": [ { "name": "Flavin containing dimethylaniline monoxygenase 4", "type": "synonym", "evidence": [ { "id": "A0A8V0YP40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP40/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YP40", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP40" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PRRC2C", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP40", "locus": { "chromosome": "8", "start_pos": 4732389, "end_pos": 4799379, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013949", "url": "https://www.ensembl.org/id/ENSGALG00010013949" } ] } } ], "crossref": [ { "id": "424393", "url": "https://www.ncbi.nlm.nih.gov/gene/424393", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR009738", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009738", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033184", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033184", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YFV8", "url": "https://www.orthodb.org/?gene=A0A8V0YFV8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YLV9", "url": "https://www.orthodb.org/?gene=A0A8V0YLV9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YLW5", "url": "https://www.orthodb.org/?gene=A0A8V0YLW5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YLX1", "url": "https://www.orthodb.org/?gene=A0A8V0YLX1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YP40", "url": "https://www.orthodb.org/?gene=A0A8V0YP40", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14038", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14038", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14038:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14038:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07001", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07001", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YFV8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFV8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YFV8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFV8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLV9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLV9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLV9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLV9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLW5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLW5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLW5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLW5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLX1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLX1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLX1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLX1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YP40", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP40", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YP40-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP40-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSEKSGQSTKAKDGKTKYATLSLFNTYKGKSLETQKTTVATRHGLQSLGKVAISRRMPPPANLPSLKAENKGNDPNVNIVPKDGTGWASKQEQHEEEKQPEVPQTQPKPAVPAPPEAAPVAKSWANTKPGGQDGPALPVNSYFQQEFPSLPAAGDQEKSGKDKDASEEAHGPSLRPQNQDAKALGQEDGNATPAEQSDGQKAAEKRDVRLPQIPQPKMNGQQQPPISSQYRAMMPPYMFNQYPRMAYPPSMQGPTRFPNSEPSRGPRGRGPPSWCSEPIERPSILSASELKELDKFDNLDAEADEGWAGAQSEVDYTEQLNFSDDDEQGSSQKEKESGDEQTPSKDSQSPDGQKEAEEQTNAKSATQASAAATKGSYGKSSQLDQDRGPAQPSIHERGGPPLHPKSILPPHPPPPDRQLGPGRQGPFPPKPVPDEDEIWKQRRRQQSEISAAVERARKRREEEERRMEEQRKAACAEKLKRLNEKFGCMTKPSREDPLKEREREREREREREREREREREREREREREKEREREREREKEKEREREREKEEKEKLEKAKEQEREKEKENEREKEEKEREKEKEEEKPVHEAPEPVEPVVTPAVEKQESESRNNKEEKEDQAVFTRQDSGRNEKEISQVTHESEPESGSQPRPAVSSGYSKQFQKSLPPRFQRQQEQMKQQQWQQQQQGVIPQSAPSQPSSGPVPPPQHRPLYQPMQPHPQHLASMGFDPRWLMMQSYMDPRMMSGRPAMDMPPIHPGIMPPKPLMRRDQLEGSATSSDSFEHIARSAREHAVPLSEPRIMWGSDPYPHAEPQQASSPPKVLEEPDNLRSEAHLEQERVAVPAAAYPVEHNQLDSHPKTDFFREPGEVEVQKFPSRPLEDAQSLQTDTSNTKVNFEGIDENVSRSSAEELMPVGESHSSLKRSISHGSSHSLKSEEQRNETTANIPKISSRPVESKETIERIEIKPKKEVLINNRTSEGPKLEKTFKPKSETRWGPRPGYGRREEGSDRPIRRSGPIKKPVLRDMKEEREQREEREQRKEKEGEKMASEKPSKSEKSDKKEAHQVPVPQAEPETSASSSAPLAKKIVQDAAPTSASPESTQTETAAKVPVQPPTPPVSQQLPAAQPAVPQLPPAVLQQPPTQPAAQQQPQAQQPVTTVKEEKQTEKVVNKEVVEKPRLETRPVKREPGLPPRTYWKEARDRDWFPDQGYRGRGRGEYYSRGRSYRGSYGGRGRGSRGHNREYPHYRDTKPRTDHVPSGPVRQREESETRSESSDFEVIPKRRRQHGSETDSDSEVHESASDTLLSDKDSLIKGKHPKREERADGKRPTKPLSFKPENNIRVDNRSLEKTYIRDDENKPKPGFLPKGEPSRRGRGGMYRRGGRDPGGRPPRPSTIRRPAYRDNQWNPRQTEIIKPEDGEPPRRNEHYGPIPVDKRPPKFERKFDPTRERPRRQRPARPPRQDKPPRFRRLKEREAASKINEAVTSSSTTAAVTNVVTEPSNTALDVSGSKTPDLSNQNSSDQANEEWETASESSDFNERRERDEKKTADIAAQVAAKAGENTGAPKREIAKRSFSSQRPGIDRQNRRGNSGPAKPGRTFSGPRSDRRSGPPPRSGKRGPFEDQTASVPGVDPSNNNSLHQEEGGVNAAGQKTTKDASGKKREEPKAGPKKPKEKVDALSQFDLNNYASVVIIDDHPEVTVVEDSQSNLNDDGFTEVVSKKQQKRLQDEERRKKEEQTVQVWTKKGSSEKGRGQNSKLPPRFAKKQQQAAAAAAQQAQAQAQTPCTAQTAGQPPASVQPQNQAAGGATASTEFTVSGKVLQNTQAHNGLGTELWENKVPPTAVLNDISKKLGPISPPQPPSVSAWNKPLTSFGSATSPEGTKPGQEGGVELGIETIQFGAPASSGSDNEVGPVLSEKSADKLPEPKEQRQKQPRAGPIKAQKLPDLSPVENKEYKPGPIGKERSLKNRKVKDAQQGEPEGQEKSSPTSVRSPEPVTAKETKAASELSTEIGTMISVSAPEFGTSTKESVTDYTTPSHPNTVATSSTKMEETLVTNVPLPHTLPLPRRETLQQSSSLTPVSPATVDLTLKMESARKAWENSPNMGEKSSPVTSAASPIAGGSSSNSSSSNAVPSSGTYSSFSSASMPPIPVASVTPTTSLSGAGTYTTSSLSTKTASTSDPPNICKVKPQQLQTSSLASASHFSQLSCMPSLIAQQQQSPQVYVSQSAAGTAAQIPAFYMDTSHLFNTQHARLAPPSLAQQQGFQPGLSQPASVQQIPIPIYAPLQGQHQAQLSLGAAPAVSQAQELFNSSLQPYRSQQAFMQSGLSQPSPVVLSGTALHNFPTVQHQELAKAQSSLAFQQTSNTQPIPILYEHQLSQASGLGGSQLLDTHILQARATLTQASNLYSGQVQQPGQSNFYNTAQSPSALQQVTVPLPGSQLSLPNFGSTAQPLIALPQSLQPPLQHTPPQAQAQNLSRPAQVTQPFRGLIPAGTQHSMIAATGKISEMELKAFGGGIDVKPGTPPVSGRSTTPTSSPFRASSTSPNNQSNKMNSIVYQKQFQSAAAAVRMTQPFPAQFAPQAKQRAEVLQSTQRFFSEQQQSKPIGGKAQKVDENGSKPSEAIADSSGVCQDKAEEKPAPAPPAATKPVRTGPIKPQAIKTEETKS", "length": 2661, "header": "tr|A0A8V0YP40-1|A0A8V0YP40_CHICK Isoform 1 of Flavin containing dimethylaniline monoxygenase 4 OS=Gallus gallus OX=9031 GN=PRRC2C PE=1 SV=1 CANONICAL=A0A8V0YP40-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YFV8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP40/entry#A0A8V0YFV8-1", "sequence": { "sequence": "MSEKSGQSTKAKDGKTKYATLSLFNTYKGKSLETQKTTVATRHGLQSLGKVAISRRMPPPANLPSLKAENKGNDPNVNIVPKDGTGWASKQEQHEEEKQPEVPQTQPKPAVPAPPEAAPVAKSWANTKPGGQDGPALPVNSYFQQEFPSLPAAGDQEKSGKDKDASEEAHGPSLRPQNQDAKALGQEDGNATPAEQSDGQKAAEKRDVRLPQIPQPKMNGQQQPPISSQYRHPPPPDRQLGPGRQGPFPPKPVPDEDEIWKQRRRQQSEISAAVERARKRREEEERRMEEQRKAACAEKLKRLNEKFGCMTKPSREDPLKEREREREREREREREREREREREREREREKEREREREREKEKEREREREKEEKEKLEKAKEQEREKEKENEREKEEKEREKEKEEEKPVHEAPEPVEPVVTPAVEKQESESRNNKEEKEDQAVFTRQDSGRNEKEISQVTHESEPESGSQPRPAVSSGYSKQFQKSLPPRFQRQQVTS", "length": 498, "header": "tr|A0A8V0YFV8-1|A0A8V0YP40_CHICK Computationally mapped isoform of Flavin containing dimethylaniline monoxygenase 4 OS=Gallus gallus OX=9031 GN=PRRC2C PE=1 SV=1 CANONICAL=A0A8V0YP40-1" }, "locus": { "chromosome": "8", "start_pos": 4783911, "end_pos": 4770901, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033445.1", "url": "https://www.ensembl.org/id/ENSGALT00010033445.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019730.1", "url": "https://www.ensembl.org/id/ENSGALP00010019730.1" } ] } }, { "isoform_ac": "A0A8V0YLV9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP40/entry#A0A8V0YLV9-1", "sequence": { "sequence": "MSEKSGQSTKAKDGKTKYATLSLFNTYKGKSLETQKTTVATRHGLQSLGKVAISRRMPPPANLPSLKAENKGNDPNVNIVPKDGTGWASKQEQHEEEKQPEVPQTQPKPAVPAPPEAAPVAKSWANTKPGGQDGPALPVNSYFQQEFPSLPAAGDQEKSGKDKDASEEAHGPSLRPQNQDAKALGQEDGNATPAEQSDGQKAAEKRDVRLPQIPQPKMNGQQQPPISSQYRAMMPPYMFNQYPRMAYPPSMQGPTRFPNSEPSRGPRGRGPPSWCSEPIERPSILSASELKELDKFDNLDAEADEGWAGAQSEVDYTEQLNFSDDDEQGSSQKEKESGDEQTPSKDSQSPDGQKEAEEQTNAKSATQASAAATKGSYGKSSQLDQDRGPAQPSIHERGGPPLHPKSILPPHPPPPDRQLGPGRQGPFPPKPVPDEDEIWKQRRRQQSEISAAVERARKRREEEERRMEEQRKAACAEKLKRLNEKFGCMTKPSREDPLKEREREREREREREREREREREREREREREKEREREREREKEKEREREREKEEKEKLEKAKEQEREKEKENEREKEEKEREKEKEEEKPVHEAPEPVEPVVTPAVEKQESESRNNKEEKEDQAVFTRQDSGRNEKEISQVTHESEPESGSQPRPAVSSGYSKQFQKSLPPRFQRQQEQMKQQQWQQQQQGVIPQSAPSQPSSGPVPPPQHRPLYQPMQPHPQHLASMGFDPRWLMMQSYMDPRMMSGRPAMDMPPIHPGIMPPKPLMRRDQLEGSATSSDSFEHIARSAREHAVPLSEPRIMWGSDPYPHAEPQQASSPPKVLEEPDNLRSEAHLEQERVAVPAAAYPVEHNQLDSHPKTDFFREPGEVEVQKFPSRPLEDAQSLQTDTSNTKVNFEGIDENVSRSSAEELMPVGESHSSLKRSISHGSSHSLKSEEQRNETTANIPKISSRPVESKETIERIEIKPKKEVLINNRTSEGPKLEKTFKPKSETRWGPRPGYGRREEGSDRPIRRSGPIKKPVLRDMKEEREQREEREQRKEKEGEKMASEKPSKSEKSDKKEAHQVPVPQAEPETSASSSAPLAKKIVQDAAPTSASPESTQTETAAKVPVQPPTPPVSQQLPAAQPAVPQLPPAVLQQPPTQPAAQQQPQAQQPVTTVKEEKQTEKVVNKEVVEKPRLETRPVKREPGLPPRTYWKEARDRDWFPDQGYRGRGRGEYYSRGRSYRGSYGGRGRGSRGHNREYPHYRDTKPRTDHVPSGPVRQREESETRSESSDFEVIPKRRRQHGSETDSDSEVHESASDTLLSDKDSLIKGKHPKREERADGKRPTKPLSFKPENNIRVDNRSLEKTYIRDDENKPKPGFLPKGEPSRRGRGGMYRRGGRDPGGRPPRPSTIRRPAYRDNQWNPRQTEIIKPEDGEPPRRNEHYGPIPVDKRPPKFERKFDPTRERPRRQRPARPPRQDKPPRFRRLKEREAASKINEAVTSSSTTAAVTNVVTEPSNTALDVSGSKTPDLSNQNSSDQANEEWETASESSDFNERRERDEKKTADIAAQVAAKAGENTGAPKREIAKRSFSSQRPGIDRQNRRGNSGPAKPGRTFSGPRSDRRSGPPPRSGKRGPFEDQTASVPGVDPSNNNSLHQEEGGVNAAGQKTTKDASGKKREEPKAGPKKPKEKVDALSQFDLNNYASVVIIDDHPEVTVVEDSQSNLNDDGFTEVVSKKQQKRLQDEERRKKEEQTVQVWTKKGSSEKGRGQNSKLPPRFAKKQQQAAAAAAQQAQAQAQTPCTAQTAGQPPASVQPQNQAAGGATASTEFTVSGKVLQNTQAHNGLGTELWENKVPPTAVLNDISKKLGPISPPQPPSVSAWNKPLTSFGSATSPEGTKPGQEGGVELGIETIQFGAPASSGSDNEVGPVLSEKSADKLPEPKEQRQKQPRAGPIKAQKLPDLSPVENKEYKPGPIGKERSLKNRKVKDAQQGEPEGQEKSSPTSVRSPEPVTAKETKAASELSTEIGTMISVSAPEFGTSTKVPLPHTLPLPRRETLQQSSSLTPVSPATVDLTLKMESARKAWENSPNMGEKSSPVTSAASPIAGGSSSNSSSSNAVPSSGTYSSFSSASMPPIPVASVTPTTSLSGAGTYTTSSLSTKTASTSDPPNICKVKPQQLQTSSLASASHFSQLSCMPSLIAQQQQSPQVYVSQSAAAQIPAFYMDTSHLFNTQHARLAPPSLAQQQGFQPGLSQPASVQQIPIPIYAPLQGQHQAQLSLGAAPAVSQAQELFNSSLQPYRSQQAFMQSGLSQPSPVVLSGTALHNFPTVQHQELAKAQSSLAFQQTSNTQPIPILYEHQLSQASGLGGSQLLDTHILQARATLTQASNLYSGQVQQPGQSNFYNTAQSPSALQQVTVPLPGSQLSLPNFGSTAQPLIALPQSLQPPLQHTPPQAQAQNLSRPAQVTQPFRGLIPAGTQHSMIAATGKISEMELKAFGGGIDVKPGTPPVSGRSTTPTSSPFRASSTSPNNQSNKMNSIVYQKQFQSAAAAVRMTQPFPAQFAPQAKQRAEVLQSTQRFFSEQQQSKPIGGKAQKVDENGSKPSEAIADSSGVCQDKAEEKPAPAPPAATKPVRTGPIKPQAIKTEETKS", "length": 2629, "header": "tr|A0A8V0YLV9-1|A0A8V0YP40_CHICK Computationally mapped isoform of Flavin containing dimethylaniline monoxygenase 4 OS=Gallus gallus OX=9031 GN=PRRC2C PE=1 SV=1 CANONICAL=A0A8V0YP40-1" }, "locus": { "chromosome": "8", "start_pos": 4783911, "end_pos": 4734003, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033459.1", "url": "https://www.ensembl.org/id/ENSGALT00010033459.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019734.1", "url": "https://www.ensembl.org/id/ENSGALP00010019734.1" } ] } }, { "isoform_ac": "A0A8V0YLW5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP40/entry#A0A8V0YLW5-1", "sequence": { "sequence": "MSEKSGQSTKAKDGKTKYATLSLFNTYKGKSLETQKTTVATRHGLQSLGKVAISRRMPPPANLPSLKAENKGNDPNVNIVPKDGTGWASKQEQHEEEKQPEVPQTQPKPAVPAPPEAAPVAKSWANTKPGGQDGPALPVNSYFQQEFPSLPAAGDQEKSGKDKDASEEAHGPSLRPQNQDAKALGQEDGNATPAEQSDGQKAAEKRDVRLPQIPQPKMNGQQQPPISSQYRAMMPPYMFNQYPRMAYPPSMQGPTRFPNSEPSRGPRGRGPPSWCSEPIERPSILSASELKELDKFDNLDAEADEGWAGAQSEVDYTEQLNFSDDDEQGSSQKEKESGDEQTPSKDSQSPDGQKEAEEQTNAKSATQASAAATKGSYGKSSQLDQDRGPAQPSIHERGGPPLHPKSILPPHPPPPDRQLGPGRQGPFPPKPVPDEDEIWKQRRRQQSEISAAVERARKRREEEERRMEEQRKAACAEKLKRLNEKFGCMTKPSREDPLKEREREREREREREREREREREREREREREKEREREREREKEKEREREREKEEKEKLEKAKEQEREKEKENEREKEEKEREKEKEEEKPVHEAPEPVEPVVTPAVEKQESESRNNKEEKEDQAVFTRQDSGRNEKEISQVTHESEPESGSQPRPAVSSGYSKQFQKSLPPRFQRQQEQMKQQQWQQQQQGVIPQSAPSQPSSGPVPPPQHRPLYQPMQPHPQHLASMGFDPRWLMMQSYMDPRMMSGRPAMDMPPIHPGIMPPKPLMRRDQLEGSATSSDSFEHIARSAREHAVPLSEPRIMWGSDPYPHAEPQQASSPPKVLEEPDNLRSEAHLEQERVAVPAAAYPVEHNQLDSHPKTDFFREPGEVEVQKFPSRPLEDAQSLQTDTSNTKVNFEGIDENVSRSSAEELMPVGESHSSLKRSISHGSSHSLKSEEQRNETTANIPKISSRPVESKETIERIEIKPKKEVLINNRTSEGPKLEKTFKPKSETRWGPRPGYGRREEGSDRPIRRSGPIKKPVLRDMKEEREQREEREQRKEKEGEKMASEKPSKSEKSDKKEAHQVPVPQAEPETSASSSAPLAKKIVQDAAPTSASPESTQTETAAKVPVQPPTPPVSQQLPAAQPAVPQLPPAVLQQPPTQPAAQQQPQAQQPVTTVKEEKQTEKVVNKEVVEKPRLETRPVKREPGLPPRTYWKEARDRDWFPDQGYRGRGRGEYYSRGRSYRGSYGGRGRGSRGHNREYPHYRDTKPRTDHVPSGPVRQREESETRSESSDFEVIPKRRRQHGSETDSDSEVHESASDTLLSDKDSLIKGKHPKREERADGKRPTKPLSFKPENNIRVDNRSLEKTYIRDDENKPKPGFLPKGEPSRRGRGGMYRRGGRDPGGRPPRPSTIRRPAYRDNQWNPRQTEIIKPEDGEPPRRNEHYGPIPVDKRPPKFERKFDPTRERPRRQRPARPPRQDKPPRFRRLKEREAASKINEAVTSSSTTAAVTNVVTEPSNTALDVSGSKTPDLSNQNSSDQANEEWETASESSDFNERRERDEKKTADIAAQVAAKAGENTGAPKREIAKRSFSSQRPGIDRQNRRGNSGPAKPGRTFSGPRSDRRSGPPPRSGKRGPFEDQTASVPGVDPSNNNSLHQEEGGVNAAGQKTTKDASGKKREEPKAGPKKPKEKVDALSQFDLNNYASVVIIDDHPEVTVVEDSQSNLNDDGFTEVVSKKQQKRLQDEERRKKEEQTVQVWTKKGSSEKGRGQNSKLPPRFAKKQQQAAAAAAQQAQAQAQTPCTAQTAGQPPASVQPQNQAAGGATASTEFTVSGKVLQNTQAHNGLGTELWENKVPPTAVLNDISKKLGPISPPQPPSVSAWNKPLTSFGSATSPEGTKPGQEGGVELGIETIQFGAPASSGSDNEVGPVLSEKSADKLPEPKEQRQKQPRAGPIKAQKLPDLSPVENKEYKPGPIGKERSLKNRKVKDAQQGEPEGQEKSSPTSVRSPEPVTAKETKAASELSTEIGTMISVSAPEFGTSTKESVTDYTTPSHPNTVATSSTKMEETLVTNMESARKAWENSPNMGEKSSPVTSAASPIAGGSSSNSSSSNAVPSSGTYSSFSSASMPPIPVASVTPTTSLSGAGTYTTSSLSTKTASTSDPPNICKVKPQQLQTSSLASASHFSQLSCMPSLIAQQQQSPQVYVSQSAAAQIPAFYMDTSHLFNTQHARLAPPSLAQQQGFQPGLSQPASVQQIPIPIYAPLQGQHQAQLSLGAAPAVSQAQELFNSSLQPYRSQQAFMQSGLSQPSPVVLSGTALHNFPTVQHQELAKAQSSLAFQQTSNTQPIPILYEHQLSQASGLGGSQLLDTHILQARATLTQASNLYSGQVQQPGQSNFYNTAQSPSALQQVTVPLPGSQLSLPNFGSTAQPLIALPQSLQPPLQHTPPQAQAQNLSRPAQVTQPFRGLIPAGTQHSMIAATGKISEMELKAFGGGIDVKPGTPPVSGRSTTPTSSPFRASSTSPNNQSNKMNSIVYQKQFQSAAAAVRMTQPFPAQFAPQAKQRAEVLQSTQRFFSEQQQSKPIGGKAQKVDENGSKPSEAIADSSGVCQDKAEEKPAPAPPAATKPVRTGPIKPQAIKTEETKS", "length": 2624, "header": "tr|A0A8V0YLW5-1|A0A8V0YP40_CHICK Computationally mapped isoform of Flavin containing dimethylaniline monoxygenase 4 OS=Gallus gallus OX=9031 GN=PRRC2C PE=1 SV=1 CANONICAL=A0A8V0YP40-1" }, "locus": { "chromosome": "8", "start_pos": 4783911, "end_pos": 4734003, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033467.1", "url": "https://www.ensembl.org/id/ENSGALT00010033467.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019739.1", "url": "https://www.ensembl.org/id/ENSGALP00010019739.1" } ] } }, { "isoform_ac": "A0A8V0YLX1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP40/entry#A0A8V0YLX1-1", "sequence": { "sequence": "MSEKSGQSTKAKDGKTKYATLSLFNTYKGKSLETQKTTVATRHGLQSLGKVAISRRMPPPANLPSLKAENKGNDPNVNIVPKDGTGWASKQEQHEEEKQPEVPQTQPKPAVPAPPEAAPVAKSWANTKPGGQDGPALPVNSYFQQEFPSLPAAGDQEKSGKDKDASEEAHGPSLRPQNQDAKALGQEDGNATPAEQSDGQKAAEKRDVRLPQIPQPKMNGQQQPPISSQYRAMMPPYMFNQYPRMAYPPSMQGPTRFPNSEPSRGPRGRGPPSWCSEPIERPSILSASELKELDKFDNLDAEADEGWAGAQSEVDYTEQLNFSDDDEQGSSQKEKESGDEQTPSKDSQSPDGQKEAEEQTNAKSATQASAAATKGSYGKSSQLDQDRGPAQPSIHERGGPPLHPKSILPPHPPPPDRQLGPGRQGPFPPKPVPDEDEIWKQRRRQQSEISAAVERARKRREEEERRMEEQRKAACAEKLKRLNEKFGCMTKPSREDPLKEREREREREREREREREREREREREREREKEREREREREKEKEREREREKEEKEKLEKAKEQEREKEKENEREKEEKEREKEKEEEKPVHEAPEPVEPVVTPAVEKQESESRNNKEEKEDQAVFTRQDSGRNEKEISQVTHESEPESGSQPRPAVSSGYSKQFQKSLPPRFQRQQEQMKQQQWQQQQQGVIPQSAPSQPSSGPVPPPQHRPLYQPMQPHPQHLASMGFDPRWLMMQSYMDPRMMSGRPAMDMPPIHPGIMPPKPLMRRDQLEGSATSSDSFEHIARSAREHAVPLSEPRIMWGSDPYPHAEPQQASSPPKVLEEPDNLRSEAHLEQERVAVPAAAYPVEHNQLDSHPKTDFFREPGEVEVQKFPSRPLEDAQSLQTDTSNTKVNFEGIDENVSRSSAEELMPVGESHSSLKRSISHGSSHSLKSEEQRNETTANIPKISSRPVESKETIERIEIKPKKEVLINNRTSEGPKLEKTFKPKSETRWGPRPGYGRREEGSDRPIRRSGPIKKPVLRDMKEEREQREEREQRKEKEGEKMASEKPSKSEKSDKKEAHQVPVPQAEPETSASSSAPLAKKIVQDAAPTSASPESTQTETAAKVPVQPPTPPVSQQLPAAQPAVPQLPPAVLQQPPTQPAAQQQPQAQQPVTTVKEEKQTEKVVNKEVVEKPRLETRPVKREPGLPPRTYWKEARDRDWFPDQGYRGRGRGEYYSRGRSYRGSYGGRGRGSRGHNREYPHYRDTKPRTDHVPSGPVRQREESETRSESSDFEVIPKRRRQHGSETDSDSEVHESASDTLLSDKDSLIKGKHPKREERADGKRPTKPLSFKPENNIRVDNRSLEKTYIRDDENKPKPGFLPKGEPSRRGRGGMYRRGGRDPGGRPPRPSTIRRPAYRDNQWNPRQTEIIKPEDGEPPRRNEHYGPIPVDKRPPKFERKFDPTRERPRRQRPARPPRQDKPPRFRRLKEREAASKINEAVTSSSTTAAVTNVVTEPSNTALDVSGSKTPDLSNQNSSDQANEEWETASESSDFNERRERDEKKTADIAAQVAAKAGENTGAPKREIAKRSFSSQRPGIDRQNRRGNSGPAKPGRTFSGPRSDRRSGPPPRSGKRGPFEDQTASVPGVDPSNNNSLHQEEGGVNAAGQKTTKDASGKKREEPKAGPKKPKEKVDALSQFDLNNYASVVIIDDHPEVTVVEDSQSNLNDDGFTEVVSKKQQKRLQDEERRKKEEQTVQVWTKKGSSEKGRGQNSKLPPRFAKKQQQAAAAAAQQAQAQAQTPCTAQTAGQPPASVQPQNQAAGGATASTEFTVSGKVLQNTQAHNGLGTELWENKVPPTAVLNDISKKLGPISPPQPPSVSAWNKPLTSFGSATSPEGTKPGQEGGVELGIETIQFGAPASSGSDNEVGPVLSEKSADKLPEPKEQRQKQPRAGPIKAQKLPDLSPVENKEYKPGPIGKERSLKNRKVKDAQQGEPEGQEKSSPTSVRSPEPVTAKETKAASELSTEIGTMISVSAPEFGTSTKESVTDYTTPSHPNTVATSSTKMEETLVTNVPLPHTLPLPRRETLQQSSSLTPVSPATVDLTLKMESARKAWENSPNMGEKSSPVTSAASPIAGGSSSNSSSSNAVPSSGTYSSFSSASMPPIPVASVTPTTSLSGAGTYTTSSLSTKTASTSDPPNICKVKPQQLQTSSLASASHFSQLSCMPSLIAQQQQSPQVYVSQSAAAQIPAFYMDTSHLFNTQHARLAPPSLAQQQGFQPGLSQPASVQQIPIPIYAPLQGQHQAQLSLGAAPAVSQAQELFNSSLQPYRSQQAFMQSGLSQPSPVVLSGTALHNFPTVQHQELAKAQSSLAFQQTSNTQPIPILYEHQLSQASGLGGSQLLDTHILQARATLTQASNLYSGQVQQPGQSNFYNTAQSPSALQQVTVPLPGSQLSLPNFGSTAQPLIALPQSLQPPLQHTPPQAQAQNLSRPAQVTQPFRGLIPAGTQHSMIAATGKISEMELKAFGGGIDVKPGTPPVSGRSTTPTSSPFRASSTSPNNQSNKMNSIVYQKQFQSAAAAVRMTQPFPAQFAPQAKQRAEVLQSTQRFFSEQQQSKPIGGKAQKVDENGSKPSEAIADSSGVCQDKAEEKPAPAPPAATKPVRTGPIKPQAIKTEETKS", "length": 2658, "header": "tr|A0A8V0YLX1-1|A0A8V0YP40_CHICK Computationally mapped isoform of Flavin containing dimethylaniline monoxygenase 4 OS=Gallus gallus OX=9031 GN=PRRC2C PE=1 SV=1 CANONICAL=A0A8V0YP40-1" }, "locus": { "chromosome": "8", "start_pos": 4783911, "end_pos": 4734003, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033471.1", "url": "https://www.ensembl.org/id/ENSGALT00010033471.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019744.1", "url": "https://www.ensembl.org/id/ENSGALP00010019744.1" } ] } }, { "isoform_ac": "A0A8V0YP40-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP40/entry#A0A8V0YP40-1", "sequence": { "sequence": "MSEKSGQSTKAKDGKTKYATLSLFNTYKGKSLETQKTTVATRHGLQSLGKVAISRRMPPPANLPSLKAENKGNDPNVNIVPKDGTGWASKQEQHEEEKQPEVPQTQPKPAVPAPPEAAPVAKSWANTKPGGQDGPALPVNSYFQQEFPSLPAAGDQEKSGKDKDASEEAHGPSLRPQNQDAKALGQEDGNATPAEQSDGQKAAEKRDVRLPQIPQPKMNGQQQPPISSQYRAMMPPYMFNQYPRMAYPPSMQGPTRFPNSEPSRGPRGRGPPSWCSEPIERPSILSASELKELDKFDNLDAEADEGWAGAQSEVDYTEQLNFSDDDEQGSSQKEKESGDEQTPSKDSQSPDGQKEAEEQTNAKSATQASAAATKGSYGKSSQLDQDRGPAQPSIHERGGPPLHPKSILPPHPPPPDRQLGPGRQGPFPPKPVPDEDEIWKQRRRQQSEISAAVERARKRREEEERRMEEQRKAACAEKLKRLNEKFGCMTKPSREDPLKEREREREREREREREREREREREREREREKEREREREREKEKEREREREKEEKEKLEKAKEQEREKEKENEREKEEKEREKEKEEEKPVHEAPEPVEPVVTPAVEKQESESRNNKEEKEDQAVFTRQDSGRNEKEISQVTHESEPESGSQPRPAVSSGYSKQFQKSLPPRFQRQQEQMKQQQWQQQQQGVIPQSAPSQPSSGPVPPPQHRPLYQPMQPHPQHLASMGFDPRWLMMQSYMDPRMMSGRPAMDMPPIHPGIMPPKPLMRRDQLEGSATSSDSFEHIARSAREHAVPLSEPRIMWGSDPYPHAEPQQASSPPKVLEEPDNLRSEAHLEQERVAVPAAAYPVEHNQLDSHPKTDFFREPGEVEVQKFPSRPLEDAQSLQTDTSNTKVNFEGIDENVSRSSAEELMPVGESHSSLKRSISHGSSHSLKSEEQRNETTANIPKISSRPVESKETIERIEIKPKKEVLINNRTSEGPKLEKTFKPKSETRWGPRPGYGRREEGSDRPIRRSGPIKKPVLRDMKEEREQREEREQRKEKEGEKMASEKPSKSEKSDKKEAHQVPVPQAEPETSASSSAPLAKKIVQDAAPTSASPESTQTETAAKVPVQPPTPPVSQQLPAAQPAVPQLPPAVLQQPPTQPAAQQQPQAQQPVTTVKEEKQTEKVVNKEVVEKPRLETRPVKREPGLPPRTYWKEARDRDWFPDQGYRGRGRGEYYSRGRSYRGSYGGRGRGSRGHNREYPHYRDTKPRTDHVPSGPVRQREESETRSESSDFEVIPKRRRQHGSETDSDSEVHESASDTLLSDKDSLIKGKHPKREERADGKRPTKPLSFKPENNIRVDNRSLEKTYIRDDENKPKPGFLPKGEPSRRGRGGMYRRGGRDPGGRPPRPSTIRRPAYRDNQWNPRQTEIIKPEDGEPPRRNEHYGPIPVDKRPPKFERKFDPTRERPRRQRPARPPRQDKPPRFRRLKEREAASKINEAVTSSSTTAAVTNVVTEPSNTALDVSGSKTPDLSNQNSSDQANEEWETASESSDFNERRERDEKKTADIAAQVAAKAGENTGAPKREIAKRSFSSQRPGIDRQNRRGNSGPAKPGRTFSGPRSDRRSGPPPRSGKRGPFEDQTASVPGVDPSNNNSLHQEEGGVNAAGQKTTKDASGKKREEPKAGPKKPKEKVDALSQFDLNNYASVVIIDDHPEVTVVEDSQSNLNDDGFTEVVSKKQQKRLQDEERRKKEEQTVQVWTKKGSSEKGRGQNSKLPPRFAKKQQQAAAAAAQQAQAQAQTPCTAQTAGQPPASVQPQNQAAGGATASTEFTVSGKVLQNTQAHNGLGTELWENKVPPTAVLNDISKKLGPISPPQPPSVSAWNKPLTSFGSATSPEGTKPGQEGGVELGIETIQFGAPASSGSDNEVGPVLSEKSADKLPEPKEQRQKQPRAGPIKAQKLPDLSPVENKEYKPGPIGKERSLKNRKVKDAQQGEPEGQEKSSPTSVRSPEPVTAKETKAASELSTEIGTMISVSAPEFGTSTKESVTDYTTPSHPNTVATSSTKMEETLVTNVPLPHTLPLPRRETLQQSSSLTPVSPATVDLTLKMESARKAWENSPNMGEKSSPVTSAASPIAGGSSSNSSSSNAVPSSGTYSSFSSASMPPIPVASVTPTTSLSGAGTYTTSSLSTKTASTSDPPNICKVKPQQLQTSSLASASHFSQLSCMPSLIAQQQQSPQVYVSQSAAGTAAQIPAFYMDTSHLFNTQHARLAPPSLAQQQGFQPGLSQPASVQQIPIPIYAPLQGQHQAQLSLGAAPAVSQAQELFNSSLQPYRSQQAFMQSGLSQPSPVVLSGTALHNFPTVQHQELAKAQSSLAFQQTSNTQPIPILYEHQLSQASGLGGSQLLDTHILQARATLTQASNLYSGQVQQPGQSNFYNTAQSPSALQQVTVPLPGSQLSLPNFGSTAQPLIALPQSLQPPLQHTPPQAQAQNLSRPAQVTQPFRGLIPAGTQHSMIAATGKISEMELKAFGGGIDVKPGTPPVSGRSTTPTSSPFRASSTSPNNQSNKMNSIVYQKQFQSAAAAVRMTQPFPAQFAPQAKQRAEVLQSTQRFFSEQQQSKPIGGKAQKVDENGSKPSEAIADSSGVCQDKAEEKPAPAPPAATKPVRTGPIKPQAIKTEETKS", "length": 2661, "header": "tr|A0A8V0YP40-1|A0A8V0YP40_CHICK Isoform 1 of Flavin containing dimethylaniline monoxygenase 4 OS=Gallus gallus OX=9031 GN=PRRC2C PE=1 SV=1 CANONICAL=A0A8V0YP40-1" }, "locus": { "chromosome": "8", "start_pos": 4783911, "end_pos": 4734003, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033476.1", "url": "https://www.ensembl.org/id/ENSGALT00010033476.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019749.1", "url": "https://www.ensembl.org/id/ENSGALP00010019749.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1113, "start_aa": "Thr", "end_pos": 1113, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1113", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 2153, "start_aa": "Thr", "end_pos": 2153, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr2153", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YP40", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP40" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "hematopoietic progenitor cell differentiation", "id": "GO:0002244", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002244", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YP40", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP40" } ], "pmid": "" }, { "name": "stress granule assembly", "id": "GO:0034063", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034063", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YP40", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP40" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1342, "end_pos": 1344, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1516, "end_pos": 1518, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1633, "end_pos": 1635, "annotation": "n_glycosylation_sequon" }, { "start_pos": 190, "end_pos": 192, 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Acts by mediating the incorporation of 2 sulfur atoms from thiocarboxylated MOCS2A into precursor Z to generate a dithiolene group. 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"A0A8V0YNT7", "url": "https://www.orthodb.org/?gene=A0A8V0YNT7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23404", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23404", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02391", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02391", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "26333", "url": "https://www.rhea-db.org/rhea/26333", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A140T8H0", "url": "https://www.uniprot.org/uniprotkb/A0A140T8H0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A140T8H0-1", "url": "https://www.uniprot.org/uniprotkb/A0A140T8H0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YFX8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFX8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": 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"MAECTHLFRNLSVFLPISSGLLSSGIKWFLLFGRSTCFLEISFWSCRQETKLPSSHQLVEAESVHVLLGTTRNNFEGKKVIHLEYEAYTSMAEMEIKKICRDVRQKWPSVKHIALHHRLGVVPVTEASVIIAVSSPHRAESLEAVTHCINTLKAIVPIWKKEIYEDEYSWKENKECFWTNSEK", "length": 183, "header": "tr|A0A8V0YFX8-1|A0A8V0YNT7_CHICK Computationally mapped isoform of Molybdenum cofactor synthesis 2 OS=Gallus gallus OX=9031 GN=MOCS2 PE=4 SV=1 CANONICAL=A0A8V0YNT7-1" }, "locus": { "chromosome": "Z", "start_pos": 16477112, "end_pos": 16471950, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030687.1", "url": "https://www.ensembl.org/id/ENSGALT00010030687.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017792.1", "url": "https://www.ensembl.org/id/ENSGALP00010017792.1" } ] } }, { "isoform_ac": "A0A8V0YNT7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNT7/entry#A0A8V0YNT7-1", "sequence": { "sequence": "ACAPRASLCRSGSPPCSSGKRSLRFIPGLLSSGIKWFLLFGRSTCFLEISFWSCRQETKLPSSHQLVEAESVHVLLGTTRNNFEGKKVIHLEYEAYTSMAEMEIKKICRDVRQKWPSVKHIALHHRLGVVPVTEASVIIAVSSPHRAESLEAVTHCINTLKAIVPIWKKEIYEDEYSWKENKECFWTNSEK", "length": 191, "header": "tr|A0A8V0YNT7-1|A0A8V0YNT7_CHICK Isoform 1 of Molybdenum cofactor synthesis 2 OS=Gallus gallus OX=9031 GN=MOCS2 PE=4 SV=1 CANONICAL=A0A8V0YNT7-1" }, "locus": { "chromosome": "Z", "start_pos": 16479753, "end_pos": 16471950, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030692.1", "url": "https://www.ensembl.org/id/ENSGALT00010030692.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017799.1", "url": "https://www.ensembl.org/id/ENSGALP00010017799.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "gga:427199", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427199", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A4X1SNL9-1", "protein_name": "Molybdopterin synthase catalytic subunit", "gene_name": "MOCS2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSSLEISSSCCNQEMKLPLSPPLVEGSAFVPPGKDMNEVEEKSKDIIKFTSEKLSIDEASQLVISPVCGAVSLFVGTTRNNFEGKKVISLEYEAYLPMAENEVRKICSDIRQKWPVRHIAVFHRLGLVPVSEASIIIAVSSAHRAASLEAVSYAIDNLKAKVPIWKKEMYEESPSSWKRNKECFWATSDSTT", "length": 192 }, "evidence": [ { "id": "A0A8V0YNT7", "url": "https://omabrowser.org/oma/group/A0A8V0YNT7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8M6Z1C5-1", "protein_name": "Molybdopterin synthase catalytic subunit", "gene_name": "mocs2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAADGGRDLITLTTDKLFADRVSESVTCPSCGAVSLFIGTTRDNFEGKKVVRLEYEAYAPMAESKLKKICSHIRTKWPSVRHINIQHRLGLVSVTEASVIIGISSPHRSDSLEALKYCIDTLKATVPIWKKEIYESGEPCWKENKECLWADGGKHPKES", "length": 159 }, "evidence": [ { "id": "A0A8V0YNT7", "url": "https://omabrowser.org/oma/group/A0A8V0YNT7/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A4FUY7-1", "protein_name": "Molybdopterin synthase catalytic subunit", "gene_name": "MOCS2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSSLEISSSCFNQETKLPLSLPLVEGSTFEPPGKDMNEVEEKSKDIIKFTSEKLSVDEVSQLVISPLCGAISLFVGTTRNNFEGKKVISLEYEAYLPMAENEIRKICSDMRQKWPVRHIAVFHRLGLVPVTEASVIIAVSSAHRAASLEAVSYAIDALKARVPIWKKEIYEESSSSWKRNKECFWATSD", "length": 189 }, "evidence": [ { "id": "A0A8V0YNT7", "url": "https://omabrowser.org/oma/group/A0A8V0YNT7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "O96007-1", "protein_name": "Molybdopterin synthase catalytic subunit", "gene_name": "MOCS2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSSLEISSSCFSLETKLPLSPPLVEDSAFEPSRKDMDEVEEKSKDVINFTAEKLSVDEVSQLVISPLCGAISLFVGTTRNNFEGKKVISLEYEAYLPMAENEVRKICSDIRQKWPVKHIAVFHRLGLVPVSEASIIIAVSSAHRAASLEAVSYAIDTLKAKVPIWKKEIYEESSTWKGNKECFWASNS", "length": 188 }, "evidence": [ { "id": "A0A8V0YNT7", "url": "https://omabrowser.org/oma/group/A0A8V0YNT7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q6AY59-1", "protein_name": "Molybdopterin synthase catalytic subunit", "gene_name": "Mocs2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSSLEINNSCFSLETKLPSSHQSVEDSASEPSGYEAKDPPQDTLKDVDDVLEKPKDIIQFTAKKLSVGEVSQLVVSPLCGAVSLFVGTTRNNFEGKKVISLEYEAYLPMAENEIRKICNDIRQKWPVRHIAVFHRLGLVPVSEASTVIAVSSAHRAASLEAVSYAIDSLKAKVPIWKKEIYEESTSSWKRNKECFWAADD", "length": 200 }, "evidence": [ { "id": "A0A8V0YNT7", "url": "https://omabrowser.org/oma/group/A0A8V0YNT7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q86HF4-1", "protein_name": "Molybdopterin synthase catalytic subunit", "gene_name": "mocs2l", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSKESRIFIEISENIIDLNYWYKIVSDDSSGATSSFLGTTRNEFKGKSVERLEYETYEPMAIKEIEKICKTILNGFENDIKKIGIVHRIGNVPVGESSILIVISSGHRKSSLEAVHYAIDTIKSTVPIWKKEFYTDGSENQWKGNCESCHFNNNNHPH", "length": 158 }, "evidence": [ { "id": "A0A8V0YNT7", "url": "https://omabrowser.org/oma/group/A0A8V0YNT7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "transferase activity", "id": "GO:0016740", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016740", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNT7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNT7" } ], "pmid": "" }, { "name": "molybdopterin synthase activity", "id": "GO:0030366", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030366", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNT7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNT7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "Mo-molybdopterin cofactor biosynthetic process", "id": "GO:0006777", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006777", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNT7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNT7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNT7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNT7" } ], "pmid": "" }, { "name": "molybdopterin synthase complex", "id": "GO:1990140", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990140", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNT7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNT7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "26333", "name": "", "equation": "2 [molybdopterin-synthase sulfur-carrier protein]-C-terminal-Gly-aminoethanethioate + cyclic pyranopterin phosphate + H2O = molybdopterin + 2 [molybdopterin-synthase sulfur-carrier protein]-C-terminal Gly-Gly + 2 H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YNT7-1" ], "evidence": [ { "id": "26333", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/26333" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A8V0YNT7", "gene_name": "MOCS2", "activity": [ { "ec_number": "2.8.1.12", "activity": "2 [molybdopterin-synthase sulfur-carrier protein]-C-terminal-Gly-aminoethanethioate + cyclic pyranopterin phosphate + H2O = molybdopterin + 2 [molybdopterin-synthase sulfur-carrier protein]-C-terminal Gly-Gly + 2 H(+).", "evidence": [ { "id": "A0A8V0YNT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNT7" } ] }, { "ec_number": "2.8.1.12", "activity": "", "evidence": [ { "id": "A0A8V0YNT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNT7" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.8.1.12", "ec_name": "2 [molybdopterin-synthase sulfur-carrier protein]-C-terminal-Gly-aminoethanethioate + cyclic pyranopterin phosphate + H2O = molybdopterin + 2 [molybdopterin-synthase sulfur-carrier protein]-C-terminal Gly-Gly + 2 H(+).", "evidence": [ { "id": "2.8.1.12", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:2.8.1.12" }, { "id": "2.8.1.12", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.8.1.12" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YP54-1", "uniprot_ac": "A0A8V0YP54", "uniprot_id": "A0A8V0YP54_CHICK", "mass": { "chemical_mass": 44545.0, "monoisotopic_mass": 44545.0 }, "refseq": { "ac": "XP_417446", "name": "uncharacterized protein C20orf96 homolog isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_417446" }, "gene_names": [ { "name": "C20orf96", "type": "recommended", "evidence": [ { "id": "A0A8V0YP54", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP54" } ] }, { "name": "C20orf96", "type": "synonym", "evidence": [ { "id": "XP_417446", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_417446" } ] } ], "protein_names": [ { "name": "Uncharacterized protein", "type": "synonym", "evidence": [ { "id": "A0A8V0YP54", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP54/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein C20orf96 homolog isoform X1", "type": "synonym", "evidence": [ { "id": "XP_417446", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_417446" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052551.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_417446.3. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_417446", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_417446" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YP54", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP54" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "C20orf96", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP54", "locus": {} } ], "crossref": [ { "id": "A0A8V0YP54", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YP54", "database": "AlphaFoldDB", "categories": [] }, { "id": "419273", "url": "https://www.ncbi.nlm.nih.gov/gene/419273", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR029236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:419273", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419273", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CNHEDFL", "url": "https://omabrowser.org/oma/group/CNHEDFL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YFY5", "url": "https://www.orthodb.org/?gene=A0A8V0YFY5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YP54", "url": "https://www.orthodb.org/?gene=A0A8V0YP54", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR28574", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28574", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR28574:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28574:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15397", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15397", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_417446", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_417446", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YFY5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFY5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YFY5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFY5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YP54", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP54", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YP54-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP54-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDAKGPGPSAAAEAKRRVGSTWQKAAAERKLAAHELVLPPITDGAKKKGQKNKSAVFVSSKTTPLVLKASPQEKYRTYTERKSALKEAELAEMLEEIRVTTHLTKLKTKAIEELKQCSDHLAKTNCWLMKDIQHTDDSTAKQARDLLHQYEVYQMIEAMTQTVSQNQLDMARAELQEMEKTMEKNVGKLQQQLDEVTSKVQVLQDELSTLRAYTEVQYLNQAMQIVLLLSNIQNLKKQQQDEIEQTEKMGQAILEELEKKAQLEQEEILQKVVEEVLLHQDGLKQMVINNHVLRREIIRQKEIIKDLEEEISELKRSVQTLRQSARDPREMIFADVFLHRPKCTPDTEVVLRIPTEKTPLPRCPQRSDEEPTNAALPSPAALLPPGPARLL", "length": 391, "header": "tr|A0A8V0YP54-1|A0A8V0YP54_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN=C20orf96 PE=4 SV=1 CANONICAL=A0A8V0YP54-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YFY5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP54/entry#A0A8V0YFY5-1", "sequence": { "sequence": "MDAKGPGPSAAAEAKRRVGSTWQKAAAERKLAAHELVLPPITDGAKKKGQKNKSAVFVSSKTTPLVLKASPQEKYRTYTERKSALKEAELAEMLEEIRVTTMIEAMTQTVSQNQLDMARAELQEMEKTMEKNVGKLQQQLDEVTSKVQVLQDELSTLRAYTEVQYLNQAMQIVLLLSNIQNLKKQQQDEIEQTEKMGQAILEELEKKAQLEQEEILQKVVEEVLLHQDGLKQMVINNHVLRREIIRQKEIIKDLEEEISELKRSVQTLRQSARDPREMIFADVFLHRPKCTPDTEVVLRIPTEKTPLPRCPQRSDEEPTNAALPSPAALLPPGPARLL", "length": 338, "header": "tr|A0A8V0YFY5-1|A0A8V0YP54_CHICK Computationally mapped isoform of Uncharacterized protein OS=Gallus gallus OX=9031 GN=C20orf96 PE=4 SV=1 CANONICAL=A0A8V0YP54-1" }, "locus": { "chromosome": "20", "start_pos": 10325074, "end_pos": 10318457, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033499.1", "url": "https://www.ensembl.org/id/ENSGALT00010033499.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019756.1", "url": "https://www.ensembl.org/id/ENSGALP00010019756.1" } ] } }, { "isoform_ac": "A0A8V0YP54-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP54/entry#A0A8V0YP54-1", "sequence": { "sequence": "MDAKGPGPSAAAEAKRRVGSTWQKAAAERKLAAHELVLPPITDGAKKKGQKNKSAVFVSSKTTPLVLKASPQEKYRTYTERKSALKEAELAEMLEEIRVTTHLTKLKTKAIEELKQCSDHLAKTNCWLMKDIQHTDDSTAKQARDLLHQYEVYQMIEAMTQTVSQNQLDMARAELQEMEKTMEKNVGKLQQQLDEVTSKVQVLQDELSTLRAYTEVQYLNQAMQIVLLLSNIQNLKKQQQDEIEQTEKMGQAILEELEKKAQLEQEEILQKVVEEVLLHQDGLKQMVINNHVLRREIIRQKEIIKDLEEEISELKRSVQTLRQSARDPREMIFADVFLHRPKCTPDTEVVLRIPTEKTPLPRCPQRSDEEPTNAALPSPAALLPPGPARLL", "length": 391, "header": "tr|A0A8V0YP54-1|A0A8V0YP54_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN=C20orf96 PE=4 SV=1 CANONICAL=A0A8V0YP54-1" }, "locus": { "chromosome": "20", "start_pos": 10325074, "end_pos": 10318457, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033503.1", "url": "https://www.ensembl.org/id/ENSGALT00010033503.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019759.1", "url": "https://www.ensembl.org/id/ENSGALP00010019759.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:419273", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419273", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A5G2QVU6-1", "protein_name": "Chromosome 17 C20orf96 homolog", "gene_name": "C17H20orf96", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MARVFPKPDHDGICSTVHQFQILDYVPWQRSKPKAKTSSLPPISQTTDTKKSKMKILTTVQPGVQARPTLWMTSQPRNPLELRRGKLDSGKTHNKIRLLRTMLRHRQASHQELCNHEDFLTQLNRELIKAIQDTEDSSALKVRVMLQQHDVFMTIISILEYSNKKRLQQMEHELQEWEEKEESKMHSLEQQVEQLNAKIEKVHEKVSFVSTYKDHEYPIKSVQVASLVRQLQQTKDSQQDELDDLGEMCRMVLASISSQIQKKKKALLGSLVLKIQHAHQETLLQKTLDSQAMLTYMDKVQKFMDQFEEEIPLLRAQMEQLQFQIWEPREIVFADVLLRRSKCTPDTDVILNIPVEELLPF", "length": 361 }, "evidence": [ { "id": "A0A8V0YP54", "url": "https://omabrowser.org/oma/group/A0A8V0YP54/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0AAA9T159-1", "protein_name": "Chromosome 13 C20orf96 homolog", "gene_name": "C13H20orf96", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGVFSRPNTLQTQPLWDRLHSPPVPGSGWQSKPTLWMTSQPRNPLELRRGKLDSGKTQATIRLMRTMLRNRRTSYQELCDHEEFLTNHCGELIKTIQDTEDSAALKVRMLLQQQDVYMTITDILEYSNKKKLHQMKCELQEWEEKEEAKIRNLEQQVEQLDAQIEKVREQVSFVSTYKDHEYPIKLVQVGNLVRQLQQVKDSQLDELDELSEMCRMVLASMSNQIQNKKKNLLRSLVVKIQRANQETLLQKTWNTRVILKYMDKFQEFIDRFEEEIPRLRAEMEQLEFQIWEPREIVFADVLLRRSKCTPDMDVVLNIPVEEPLPF", "length": 326 }, "evidence": [ { "id": "A0A8V0YP54", "url": "https://omabrowser.org/oma/group/A0A8V0YP54/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0ABK0M1F2-1", "protein_name": "Similar to human chromosome 20 open reading frame 96", "gene_name": "C3h20orf96", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAQKRINSRTQFAGHKLQVHMSSGAEKNLKPSTLPPLRQAKGHSKRKTKSVTKIQPVAQSQVSVDMTTATKTPRALRRRDQPHHGKVQAKVRLMKSMLRNQRTSLQELYSHEGYLSKLNQELIKTILETEDSTALSVREMLQQQNILGNIIDILEYSNKKRVQELRSEFQEWKEKEESKTNTLQWEVEQLNSEIRKANEEVNLLSTYMDHEYPIRLVQIANHVRLVQQAKDSQQDELDNLREMREKVLAFFSNIIQEKKRRILKSLVVKTQEPHENRLLLKTRDSRRLQRCVLWFEELIKQLKEEIPMLISEVEQMYAEIWNPREAVFKDVLLQRPKCTPDMAVELNIPTQELFPF", "length": 356 }, "evidence": [ { "id": "A0A8V0YP54", "url": "https://omabrowser.org/oma/group/A0A8V0YP54/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9NUD7-1", "protein_name": "Uncharacterized protein C20orf96", "gene_name": "C20orf96", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAHVLQKPKHSGTHSIVQEFQVPDYVPWQQSKQETKPSTLPPVQQANSLHTSKMKTLTRVQPVFHFKPTTVVTSCQPKNPRELHRRRKLDPGKMHAKIWLMKTSLRSGRAALRELRSRENFLSKLNRELIETIQEMENSTTLHVRALLQQQDTLATIIDILEYSNKKRLQQLKSELQEWEEKKKCKMSYLEQQAEQLNAKIEKTQEEVNFLSTYMDHEYSIKSVQISTLMRQLQQVKDSQQDELDDLGEMRRKVLESLSDKIQKKKKKILSSVVAETQRPYEEALLQKMWESQDFLKCMQRFREIIDQFEENMPVLRAEVEELQAQTREPREVIFEDVLLRRPKCTPDMDVILNIPVEEPLPF", "length": 363 }, "evidence": [ { "id": "A0A8V0YP54", "url": "https://omabrowser.org/oma/group/A0A8V0YP54/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 52, "end_pos": 54, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 52, "end_pos": 54 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YMX1-1", "uniprot_ac": "A0A8V0YMX1", "uniprot_id": "A0A8V0YMX1_CHICK", "mass": { "chemical_mass": 71650.0, "monoisotopic_mass": 71650.0 }, "refseq": {}, "gene_names": [ { "name": "C5orf51", "type": "recommended", "evidence": [ { "id": "A0A8V0YMX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMX1" } ] } ], "protein_names": [ { "name": "F-box protein 4", "type": "synonym", "evidence": [ { "id": "A0A8V0YMX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMX1/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMX1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMX1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "C5orf51", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMX1", "locus": {} } ], "crossref": [ { "id": "A0A8V0YMX1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YMX1", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd11656", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11656", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd22085", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22085", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001810", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001810", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036047", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036047", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037657", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037657", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YG10", "url": "https://www.orthodb.org/?gene=A0A8V0YG10", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YMX1", "url": "https://www.orthodb.org/?gene=A0A8V0YMX1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR28494", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28494", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR28494:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28494:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF12937", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12937", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17716", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17716", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YG10", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG10", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YG10-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG10-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YMX1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMX1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YMX1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMX1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASEGGKGCNATLRLCSPQLPREGAVRRELLRVCTALPLRLWRRPVAFASRGAERGDVRRRWGMAEAGSVVSALEPRLEALGRRLAAPRGAGGDGIFLAKGSAALEKLKDLCKEGKEKARHSTLLQLYTQAVLDVTYFEESQLVDEDFAGESSLQKVKELICILSDPEDLVRECSINEEPINILGTDLVECLYWRKGALLYMYCHTAKERSEWLRGNIALFKKCLNDGVHYLKRMLSFRCPLHLDGDVLLQDKDTARLLSEGVFSDTHLLAMMYSGEMCYWGLKYCGEGKQESLKMMDSVSDGDLGSRSQGALIDVQLYIMSFLTPQDLCRLGCTSCYWRVAVQDPLLWRNFLLRDLPIWTSVDWKSLPATEIFNKAFSQGSDEAMYDYMAVYKKSCPQTRRSLKSSRPRYGAVTSFLQSLVTQTEPRFAMFGPGLEELDDSLVRKMMTCPEILLVAGLPQRRIHGIGSGVSFQINNNQKFNIVTLYSTTSVERKRAREEQAAVVNKMFYQENSTVGNQQAVQYNVIAQVKKVCEVVDGFIYVANAEAHKKHDREEELAHILAMIDPALGPPNRPLLVLSCVSHFGVERIPCVYMAHQLQLNLLPRPWMVQDTVAATLSGLLSGIEWLLEEADCKNAQ", "length": 638, "header": "tr|A0A8V0YMX1-1|A0A8V0YMX1_CHICK Isoform 1 of F-box protein 4 OS=Gallus gallus OX=9031 GN=C5orf51 PE=1 SV=1 CANONICAL=A0A8V0YMX1-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YG10-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMX1/entry#A0A8V0YG10-1", "sequence": { "sequence": "MQFSFRQVRRESWRNNVWKHIIAVLTQNNKCQLPSFGIFLAKGSAALEKLKDLCKEGKEKARHSTLLQLYTQAVLDVTYFEESQLVDEDFAGESSLQKVKELICILSDPEDLVRECSINEEPINILGTDLVECLYWRKGALLYMYCHTAKERSEWLRGNIALFKKCLNDGVHYLKRMLSFRCPLHLDGDVLLQDKDTARLLSEGVFSDTHLLAMMYSGEMCYWGLKYCGEGKQESLKMMDSVSDGDLGSRSQGALVDFRELGKTMLTKYVAVCEGPLKDQGWNTISANEMLCYLRKVHS", "length": 299, "header": "tr|A0A8V0YG10-1|A0A8V0YMX1_CHICK Computationally mapped isoform of F-box protein 4 OS=Gallus gallus OX=9031 GN=C5orf51 PE=1 SV=1 CANONICAL=A0A8V0YMX1-1" }, "locus": { "chromosome": "Z", "start_pos": 13809021, "end_pos": 13805800, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030052.1", "url": "https://www.ensembl.org/id/ENSGALT00010030052.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017464.1", "url": "https://www.ensembl.org/id/ENSGALP00010017464.1" } ] } }, { "isoform_ac": "A0A8V0YMX1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMX1/entry#A0A8V0YMX1-1", "sequence": { "sequence": "MASEGGKGCNATLRLCSPQLPREGAVRRELLRVCTALPLRLWRRPVAFASRGAERGDVRRRWGMAEAGSVVSALEPRLEALGRRLAAPRGAGGDGIFLAKGSAALEKLKDLCKEGKEKARHSTLLQLYTQAVLDVTYFEESQLVDEDFAGESSLQKVKELICILSDPEDLVRECSINEEPINILGTDLVECLYWRKGALLYMYCHTAKERSEWLRGNIALFKKCLNDGVHYLKRMLSFRCPLHLDGDVLLQDKDTARLLSEGVFSDTHLLAMMYSGEMCYWGLKYCGEGKQESLKMMDSVSDGDLGSRSQGALIDVQLYIMSFLTPQDLCRLGCTSCYWRVAVQDPLLWRNFLLRDLPIWTSVDWKSLPATEIFNKAFSQGSDEAMYDYMAVYKKSCPQTRRSLKSSRPRYGAVTSFLQSLVTQTEPRFAMFGPGLEELDDSLVRKMMTCPEILLVAGLPQRRIHGIGSGVSFQINNNQKFNIVTLYSTTSVERKRAREEQAAVVNKMFYQENSTVGNQQAVQYNVIAQVKKVCEVVDGFIYVANAEAHKKHDREEELAHILAMIDPALGPPNRPLLVLSCVSHFGVERIPCVYMAHQLQLNLLPRPWMVQDTVAATLSGLLSGIEWLLEEADCKNAQ", "length": 638, "header": "tr|A0A8V0YMX1-1|A0A8V0YMX1_CHICK Isoform 1 of F-box protein 4 OS=Gallus gallus OX=9031 GN=C5orf51 PE=1 SV=1 CANONICAL=A0A8V0YMX1-1" }, "locus": { "chromosome": "Z", "start_pos": 13817459, "end_pos": 13806111, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030065.1", "url": "https://www.ensembl.org/id/ENSGALT00010030065.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017468.1", "url": "https://www.ensembl.org/id/ENSGALP00010017468.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "mitophagy", "id": "GO:0000423", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000423", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMX1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMX1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 10, "end_pos": 12, "annotation": "n_glycosylation_sequon" }, { "start_pos": 513, "end_pos": 515, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YMX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMX1" }, { "id": "PF12937", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12937" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "F-box", "eco_id": "ECO_0000259", "start_pos": 315, "end_pos": 354, "start_aa": "Asp", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 10, "end_pos": 12 }, { "start_pos": 513, "end_pos": 515 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YPB8-1", "uniprot_ac": "A0A8V0YPB8", "uniprot_id": "A0A8V0YPB8_CHICK", "mass": { "chemical_mass": 40416.0, "monoisotopic_mass": 40416.0 }, "refseq": { "ac": "XP_040526061", "name": "zeta-sarcoglycan isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040526061" }, "gene_names": [ { "name": "SGCZ", "type": "recommended", "evidence": [ { "id": "A0A8V0YPB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPB8" } ] }, { "name": "SGCZ", "type": "synonym", "evidence": [ { "id": "XP_040526061", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040526061" } ] } ], "protein_names": [ { "name": "Sarcoglycan zeta", "type": "synonym", "evidence": [ { "id": "A0A8V0YPB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPB8/entry#names_and_taxonomy" } ] }, { "name": "zeta-sarcoglycan isoform X2", "type": "synonym", "evidence": [ { "id": "XP_040526061", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040526061" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052576.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040526061", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040526061" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPB8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPB8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SGCZ", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPB8", "locus": { "chromosome": "4", "start_pos": 63734268, "end_pos": 63377306, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010014042", "url": "https://www.ensembl.org/id/ENSGALG00010014042" } ] } } ], "crossref": [ { "id": "A0A8V0YPB8", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YPB8", "database": "AlphaFoldDB", "categories": [] }, { "id": "422739", "url": "https://www.ncbi.nlm.nih.gov/gene/422739", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006875", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006875", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039972", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039972", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YG60", "url": "https://www.orthodb.org/?gene=A0A8V0YG60", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YM74", "url": "https://www.orthodb.org/?gene=A0A8V0YM74", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YMK3", "url": "https://www.orthodb.org/?gene=A0A8V0YMK3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YPB8", "url": "https://www.orthodb.org/?gene=A0A8V0YPB8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YUC0", "url": "https://www.orthodb.org/?gene=A0A8V0YUC0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YUD2", "url": "https://www.orthodb.org/?gene=A0A8V0YUD2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12939", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12939", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12939:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12939:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04790", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04790", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-9913351", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9913351", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_040526061", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040526061", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YG60", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG60", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YG60-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG60-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YM74", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM74", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YM74-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM74-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YMK3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMK3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YMK3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMK3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YPB8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPB8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YPB8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPB8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YUC0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUC0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YUC0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUC0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YUD2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUD2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YUD2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUD2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDRSGNLATEELKMDEKWIIVNEEVRRPGAMTREQYILATQQNSLPRTENPQFYPVGIYGWRKRCLYFFVLLLLVTMIVNLAMTIWILKVMNFTVRLLLHFEQNFWFKFIQKESPSNAEKLPHSLSQHGDGMGNLRVTKKGIRLEGISEFLLPLYVKEINSRKDSPLVLQSDRNVTVNARNHMGQLTGQLTVGADAVEAQCKRFEVRASEGGKVLFSADEDEIVIGADRLKVTGTEGAVFGHSVETPHIRAEPSQDLKLESPTRSLVMEAPRGVQINAAAGDLKATCRKELHLQSTEGEIFLNADTIRLGNLPVGSFSSSSPSSSIPRQTIYELCVCPNGKLYLSPAGAGSTCQSSSNICLWS", "length": 363, "header": "tr|A0A8V0YPB8-1|A0A8V0YPB8_CHICK Isoform 1 of Sarcoglycan zeta OS=Gallus gallus OX=9031 GN=SGCZ PE=3 SV=1 CANONICAL=A0A8V0YPB8-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YG60-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPB8/entry#A0A8V0YG60-1", "sequence": { "sequence": "MKLYGCMDEKWIIVNEEVRRPGAMTREQYILATQQNSLPRTENPQFYPVGIYGWRKRCLYFFVLLLLVTMIVNLAMTIWILKVMNFTVRLLLHFEQNFWFKFIQKESPSNAEKLPHSLSQHGDGMGNLRVTKKGIRLEGISEFLLPLYVKEINSRKDSPLVLQSDRNVTVNARNHMGQLTGQLTVGADAVEAQCKRFEVRASEGGKVLFSADEDEIVIGADRLKVTGTEGAVFGHSVETPHIRAEPSQDLKLESPTRSLVMEAPRGVQINAAAGDLKATCRKELHLQSTEGEIFLNADTIRLGNLPVGSFSSSSPSSSIPRQTIYELCVCPNGKLYLSPAGAGSTCQSSSNICLWS", "length": 356, "header": "tr|A0A8V0YG60-1|A0A8V0YPB8_CHICK Computationally mapped isoform of Sarcoglycan zeta OS=Gallus gallus OX=9031 GN=SGCZ PE=3 SV=1 CANONICAL=A0A8V0YPB8-1" }, "locus": { "chromosome": "4", "start_pos": 63727723, "end_pos": 63380164, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033697.1", "url": "https://www.ensembl.org/id/ENSGALT00010033697.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019842.1", "url": "https://www.ensembl.org/id/ENSGALP00010019842.1" } ] } }, { "isoform_ac": "A0A8V0YM74-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPB8/entry#A0A8V0YM74-1", "sequence": { "sequence": "MDRSGNLATEELKMDEKWIIVNEEVRRPGARLLLHFEQNFWFKFIQKESPSNAEKLPHSLSQHGDGMGNLRVTKKGIRLEGISEFLLPLYVKEINSRKDSPLVLQSDRNVTVNARNHMGQLTGQLTVGADAVEAQCKRFEVRASEGGKVLFSADEDEIVIGADRLKVTGTEGAVFGHSVETPHIRAEPSQDLKLESPTRSLVMEAPRGVQINAAAGDLKATCRKELHLQSTEGEIFLNADTIRLGNLPVGSFSSSSPSSSIPRQTIYELCVCPNGKLYLSPAGAGSTCQSSSNICLWS", "length": 298, "header": "tr|A0A8V0YM74-1|A0A8V0YPB8_CHICK Computationally mapped isoform of Sarcoglycan zeta OS=Gallus gallus OX=9031 GN=SGCZ PE=3 SV=1 CANONICAL=A0A8V0YPB8-1" }, "locus": { "chromosome": "4", "start_pos": 63727723, "end_pos": 63377505, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033712.1", "url": "https://www.ensembl.org/id/ENSGALT00010033712.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019851.1", "url": "https://www.ensembl.org/id/ENSGALP00010019851.1" } ] } }, { "isoform_ac": "A0A8V0YMK3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPB8/entry#A0A8V0YMK3-1", "sequence": { "sequence": "MDRSGNLATEELKMDEKWIIVNEEVRRPGAMTREQYILATQQNSLPRTENPQFYPVGIYGWRKRCLYFFVLLLLVTMIVNLAMTIWILKVMNFTVDGMGNLRVTKKGIRLEGISEFLLPLYVKEINSRKDSPLVLQSDRNVTVNARNHMGQLTGQLTVGADAVEAQCKRFEVRASEGGKVLFSADEDEIVIGADRLKVTGTEGAVFGHSVETPHIRAEPSQDLKLESPTRSLVMEAPRGVQINAAAGDLKATCRKELHLQSTEGEIFLNADTIRLGNLPVGSFSSSSPSSSIPRQTIYELCVCPNGKLYLSPAGAGSTCQSSSNICLWS", "length": 329, "header": "tr|A0A8V0YMK3-1|A0A8V0YPB8_CHICK Computationally mapped isoform of Sarcoglycan zeta OS=Gallus gallus OX=9031 GN=SGCZ PE=3 SV=1 CANONICAL=A0A8V0YPB8-1" }, "locus": { "chromosome": "4", "start_pos": 63727723, "end_pos": 63377505, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033707.1", "url": "https://www.ensembl.org/id/ENSGALT00010033707.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019849.1", "url": "https://www.ensembl.org/id/ENSGALP00010019849.1" } ] } }, { "isoform_ac": "A0A8V0YPB8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPB8/entry#A0A8V0YPB8-1", "sequence": { "sequence": "MDRSGNLATEELKMDEKWIIVNEEVRRPGAMTREQYILATQQNSLPRTENPQFYPVGIYGWRKRCLYFFVLLLLVTMIVNLAMTIWILKVMNFTVRLLLHFEQNFWFKFIQKESPSNAEKLPHSLSQHGDGMGNLRVTKKGIRLEGISEFLLPLYVKEINSRKDSPLVLQSDRNVTVNARNHMGQLTGQLTVGADAVEAQCKRFEVRASEGGKVLFSADEDEIVIGADRLKVTGTEGAVFGHSVETPHIRAEPSQDLKLESPTRSLVMEAPRGVQINAAAGDLKATCRKELHLQSTEGEIFLNADTIRLGNLPVGSFSSSSPSSSIPRQTIYELCVCPNGKLYLSPAGAGSTCQSSSNICLWS", "length": 363, "header": "tr|A0A8V0YPB8-1|A0A8V0YPB8_CHICK Isoform 1 of Sarcoglycan zeta OS=Gallus gallus OX=9031 GN=SGCZ PE=3 SV=1 CANONICAL=A0A8V0YPB8-1" }, "locus": { "chromosome": "4", "start_pos": 63727723, "end_pos": 63377505, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033701.1", "url": "https://www.ensembl.org/id/ENSGALT00010033701.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019845.1", "url": "https://www.ensembl.org/id/ENSGALP00010019845.1" } ] } }, { "isoform_ac": "A0A8V0YUC0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPB8/entry#A0A8V0YUC0-1", "sequence": { "sequence": "MPGRAHSMGDESHLIFISSFRKMTREQYILATQQNSLPRTENPQFYPVGIYGWRKRCLYFFVLLLLVTMIVNLAMTIWILKVMNFTVDGMGNLRVTKKGIRLEGISEFLLPLYVKEINSRKDSPLVLQSDRNVTVNARNHMGQLTGQLTVGADAVEAQCKRFEVRASEGGKVLFSADEDEIVIGADRLKVTGTEGAVFGHSVETPHIRAEPSQDLKLESPTRSLVMEAPRGVQINAAAGDLKATCRKELHLQSTEGEIFLNADTIRLGNLPVGSFSSSSPSSSIPRQTIYELCVCPNGKLYLSPAGAGSTCQSSSNICLWS", "length": 321, "header": "tr|A0A8V0YUC0-1|A0A8V0YUC0_CHICK Computationally mapped isoform of Sarcoglycan zeta OS=Gallus gallus OX=9031 GN=SGCZ PE=3 SV=1 CANONICAL=A0A8V0YPB8-1" }, "locus": { "chromosome": "4", "start_pos": 63727723, "end_pos": 63573141, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033691.1", "url": "https://www.ensembl.org/id/ENSGALT00010033691.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019838.1", "url": "https://www.ensembl.org/id/ENSGALP00010019838.1" } ] } }, { "isoform_ac": "A0A8V0YUD2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPB8/entry#A0A8V0YUD2-1", "sequence": { "sequence": "MDRSGNLATEELKMTREQYILATQQNSLPRTENPQFYPVGIYGWRKRCLYFFVLLLLVTMIVNLAMTIWILKVMNFTVRLLLHFEQNFWFKFIQKESPSNAEKLPHSLSQHGDGMGNLRVTKKGIRLEGISEFLLPLYVKEINSRKDSPLVLQSDRNVTVNARNHMGQLTGQLTVGADAVEAQCKRFEVRASEGGKVLFSADEDEIVIGADRLKVTGTEGAVFGHSVETPHIRAEPSQDLKLESPTRSLVMEAPRGVQINAAAGDLKATCRKELHLQSTEGEIFLNADTIRLGNLPVGSFSSSSPSSSIPRQTIYELCVCPNGKLYLSPAGAGSTCQSSSNICLWS", "length": 346, "header": "tr|A0A8V0YUD2-1|A0A8V0YUD2_CHICK Computationally mapped isoform of Sarcoglycan zeta OS=Gallus gallus OX=9031 GN=SGCZ PE=3 SV=1 CANONICAL=A0A8V0YPB8-1" }, "locus": { "chromosome": "4", "start_pos": 63727723, "end_pos": 63377505, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033719.1", "url": "https://www.ensembl.org/id/ENSGALT00010033719.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019853.1", "url": "https://www.ensembl.org/id/ENSGALP00010019853.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-9913351", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9913351", "resource": "Reactome", "description": "Formation of the dystrophin-glycoprotein complex (DGC)" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPB8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPB8" } ], "pmid": "" }, { "name": "sarcolemma", "id": "GO:0042383", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042383", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPB8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPB8" } ], "pmid": "" }, { "name": "sarcoglycan complex", "id": "GO:0016012", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016012", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPB8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPB8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "heart contraction", "id": "GO:0060047", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060047", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPB8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPB8" } ], "pmid": "" }, { "name": "cardiac muscle tissue development", "id": "GO:0048738", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048738", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPB8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPB8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 174, "end_pos": 176, "annotation": "n_glycosylation_sequon" }, { "start_pos": 92, "end_pos": 94, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 174, "end_pos": 176 }, { "start_pos": 92, "end_pos": 94 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YPC3-1", "uniprot_ac": "A0A8V0YPC3", "uniprot_id": "A0A8V0YPC3_CHICK", "mass": { "chemical_mass": 46181.0, "monoisotopic_mass": 46181.0 }, "refseq": {}, "gene_names": [ { "name": "HM13", "type": "recommended", "evidence": [ { "id": "A0A8V0YPC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPC3" } ] } ], "protein_names": [ { "name": "Histocompatibility minor 13", "type": "synonym", "evidence": [ { "id": "A0A8V0YPC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPC3/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPC3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPC3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "HM13", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPC3", "locus": { "chromosome": "20", "start_pos": 10345584, "end_pos": 10332888, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010014047", "url": "https://www.ensembl.org/id/ENSGALG00010014047" } ] } } ], "crossref": [ { "id": "A0A8V0YPC3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YPC3", "database": "AlphaFoldDB", "categories": [] }, { "id": "100859573", "url": "https://www.ncbi.nlm.nih.gov/gene/100859573", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006639", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006639", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007369", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007369", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042524", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042524", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:100859573", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100859573", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "FLYDIWW", "url": "https://omabrowser.org/oma/group/FLYDIWW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YG64", "url": "https://www.orthodb.org/?gene=A0A8V0YG64", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YG69", "url": "https://www.orthodb.org/?gene=A0A8V0YG69", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YMK7", "url": "https://www.orthodb.org/?gene=A0A8V0YMK7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YPC3", "url": "https://www.orthodb.org/?gene=A0A8V0YPC3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12174", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12174", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12174:SF23", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12174:SF23", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04258", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04258", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-9707587", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9707587", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YG64", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG64", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YG64-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG64-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YG69", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG69", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YG69-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG69-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YMK7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMK7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YMK7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMK7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YPC3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPC3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YPC3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPC3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAEAQNGSAGPQAVPAASARPPATPEGIALAYGSLVLMALLPIFFGALRSVSCAKSKNSSEMPETITSRDAARFPIVASCTLLGLYLFFKIFSQEYINLLLSMYFFVLGILALSHTISPMMNRFFPANFPNKQYQLLFTQGSGESKEEIVNYEFDTKDLVCLALSSVVGVWYLLRKHWIANNLFGLAFSLNGVELLHLNNVSTGCILLGGLFIYDVFWVFGTNVMVTVAKSFEAPIKLVFPQDLLEKGLEADNFAMLGLGDIVIPGIFIALLLRFDISLKKNTHTYFYTSFVAYIFGLGLTIFIMHIFKHAQPALLYLVPACIGFPLLVALAKGEVTEMFRLQLSGSMHASRSCLFPESQPSQHGTGPAWSYESSAEILPHTPRLTHFPTVSGSPASLADSMQQKLSCPRRRRQQSPSAM", "length": 420, "header": "tr|A0A8V0YPC3-1|A0A8V0YPC3_CHICK Isoform 1 of Histocompatibility minor 13 OS=Gallus gallus OX=9031 GN=HM13 PE=1 SV=1 CANONICAL=A0A8V0YPC3-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YG64-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPC3/entry#A0A8V0YG64-1", "sequence": { "sequence": "MAEAQNGSAGPQAVPAASARPPATPEGIALAYGSLVLMALLPIFFGALRSVSCAKSKNSSEMPETITSRDAARFPIVASCTLLGLYLFFKIFSQEYINLLLSMYFFVLGILALSHTISPMMNRFFPANFPNKQYQLLFTQGSGESKEEIVNYEFDTKDLVCLALSSVVGVWYLLRKHWIANNLFGLAFSLNGVELLHLNNVSTGCILLGGLFIYDVFWVFGTNVMVTVAKSFEAPIKLVFPQDLLEKGLEADNFAMLGLGDIVIPGIFIALLLRFDISLKKNTHTYFYTSFVAYIFGLGLTIFIMHIFKHAQPALLYLVPACIGFPLLVALAKGEVTEMFR", "length": 341, "header": "tr|A0A8V0YG64-1|A0A8V0YPC3_CHICK Computationally mapped isoform of Histocompatibility minor 13 OS=Gallus gallus OX=9031 GN=HM13 PE=1 SV=1 CANONICAL=A0A8V0YPC3-1" }, "locus": { "chromosome": "20", "start_pos": 10342072, "end_pos": 10332966, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033704.1", "url": "https://www.ensembl.org/id/ENSGALT00010033704.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019847.1", "url": "https://www.ensembl.org/id/ENSGALP00010019847.1" } ] } }, { "isoform_ac": "A0A8V0YG69-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPC3/entry#A0A8V0YG69-1", "sequence": { "sequence": "MAEAQNGSAGPQAVPAASARPPATPEGIALAYGSLVLMALLPIFFGALRSVSCAKSKNSSEMPETITSRDAARFPIVASCTLLGLYLFFKIFSQEYINLLLSMYFFVLGILALSHTISPMMNRFFPANFPNKQYQLLFTQGSGESKEEIVNYEFDTKDLVCLALSSVVGVWYLLRKHWIANNLFGLAFSLNGVELLHLNNVSTGCILLGGLFIYDVFWVFGTNVMVTVAKSFEAPIKLVFPQDLLEKGLEADNFAMLGLGDIVIPGIFIALLLRFDISLKKNTHTYFYTSFVAYIFGLGLTIFIMHIFKHAQPALLYLVPACIGFPLLVALAKGEVTEMFSYESSAEILPHTPRLTHFPTVSGSPASLADSMQQKLSCPRRRRQQSPSAM", "length": 390, "header": "tr|A0A8V0YG69-1|A0A8V0YG69_CHICK Computationally mapped isoform of Histocompatibility minor 13 OS=Gallus gallus OX=9031 GN=HM13 PE=1 SV=1 CANONICAL=A0A8V0YPC3-1" }, "locus": { "chromosome": "20", "start_pos": 10344191, "end_pos": 10332966, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033714.1", "url": "https://www.ensembl.org/id/ENSGALT00010033714.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019852.1", "url": "https://www.ensembl.org/id/ENSGALP00010019852.1" } ] } }, { "isoform_ac": "A0A8V0YMK7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPC3/entry#A0A8V0YMK7-1", "sequence": { "sequence": "MAEAQNGSAGPQAVPAASARPPATPEGIALAYGSLVLMALLPIFFGALRSVSCAKSKNSSEMPETITSRDAARFPIVASCTLLGLYLFFKIFSQEYINLLLSMYFFVLGILALSHTISPMMNRFFPANFPNKQYQLLFTQGSGESKEEIVNYEFDTKDLVCLALSSVVGVWYLLRKHWIANNLFGLAFSLNGVELLHLNNVSTGCILLGGLFIYDVFWVFGTNVMVTVAKSFEAPIKLVFPQDLLEKGLEADNFAMLGLGDIVIPGIFIALLLRFDISLKKNTHTYFYTSFVAYIFGLGLTIFIMHIFKHAQPALLYLVPACIGFPLLVALAKGEVTEMFSYEESSTPKEAPKASKEETTEADKKEK", "length": 367, "header": "tr|A0A8V0YMK7-1|A0A8V0YMK7_CHICK Computationally mapped isoform of Histocompatibility minor 13 OS=Gallus gallus OX=9031 GN=HM13 PE=1 SV=1 CANONICAL=A0A8V0YPC3-1" }, "locus": { "chromosome": "20", "start_pos": 10344732, "end_pos": 10332966, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033720.1", "url": "https://www.ensembl.org/id/ENSGALT00010033720.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019854.1", "url": "https://www.ensembl.org/id/ENSGALP00010019854.1" } ] } }, { "isoform_ac": "A0A8V0YPC3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPC3/entry#A0A8V0YPC3-1", "sequence": { "sequence": "MAEAQNGSAGPQAVPAASARPPATPEGIALAYGSLVLMALLPIFFGALRSVSCAKSKNSSEMPETITSRDAARFPIVASCTLLGLYLFFKIFSQEYINLLLSMYFFVLGILALSHTISPMMNRFFPANFPNKQYQLLFTQGSGESKEEIVNYEFDTKDLVCLALSSVVGVWYLLRKHWIANNLFGLAFSLNGVELLHLNNVSTGCILLGGLFIYDVFWVFGTNVMVTVAKSFEAPIKLVFPQDLLEKGLEADNFAMLGLGDIVIPGIFIALLLRFDISLKKNTHTYFYTSFVAYIFGLGLTIFIMHIFKHAQPALLYLVPACIGFPLLVALAKGEVTEMFRLQLSGSMHASRSCLFPESQPSQHGTGPAWSYESSAEILPHTPRLTHFPTVSGSPASLADSMQQKLSCPRRRRQQSPSAM", "length": 420, "header": "tr|A0A8V0YPC3-1|A0A8V0YPC3_CHICK Isoform 1 of Histocompatibility minor 13 OS=Gallus gallus OX=9031 GN=HM13 PE=1 SV=1 CANONICAL=A0A8V0YPC3-1" }, "locus": { "chromosome": "20", "start_pos": 10344191, "end_pos": 10332966, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033709.1", "url": "https://www.ensembl.org/id/ENSGALT00010033709.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019850.1", "url": "https://www.ensembl.org/id/ENSGALP00010019850.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:100859573", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100859573", "resource": "KEGG Pathway" }, { "id": "R-GGA-9707587", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9707587", "resource": "Reactome", "description": "Regulation of HMOX1 expression and activity" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZP98-1", "protein_name": "MCTS family member 2", "gene_name": "Hm13", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDSALSDPHNGSSEAGTPANGTTRPPSTPEGIALAYGSLLLMALLPIFFGALRSVRCARGKSSSDMPETITSRDAARFPIIASCTLLGLYLFFKLFSQEYINLLLSMYFFVLGILALSHTISPFMNKFFPANFPNRQYQLLFTQGSGENKEEIINYEFDTKDLVCLGLSSVVGVWYLLRKHWIANNLFGLAFSLNGVELLHLNNVSTGCILLGGLFIYDIFWVFGTNVMVTVAKSFEAPIKLVFPQDLLEKGLEADNFAMLGLGDIVIPGIFIALLLRFDISLKKNTHTYFYTSFAAYIFGLGLTIFIMHIFKHAQPALLYLVPACIGFPVLVALVKGEVAEMFSYEESNPKDPAAVTESKEESTEASASKRLEKKEK", "length": 378 }, "evidence": [ { "id": "A0A8V0YPC3", "url": "https://omabrowser.org/oma/group/A0A8V0YPC3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O81062-1", "protein_name": "Signal peptide peptidase", "gene_name": "SPP", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MKNCERFANLALAGLTLAPLVVRVNPNLNVILTACITVYVGCFRSVKDTPPTETMSKEHAMRFPLVGSAMLLSLFLLFKFLSKDLVNAVLTAYFFVLGIVALSATLLPAIRRFLPNPWNDNLIVWRFPYFKSLEVEFTKSQVVAGIPGTFFCAWYAWKKHWLANNILGLSFCIQGIEMLSLGSFKTGAILLAGLFFYDIFWVFFTPVMVSVAKSFDAPIKLLFPTGDALRPYSMLGLGDIVIPGIFVALALRFDVSRRRQPQYFTSAFIGYAVGVILTIVVMNWFQAAQPALLYIVPAVIGFLASHCIWNGDIKPLLAFDESKTEEATTDESKTSEEVNKAHDE", "length": 344 }, "evidence": [ { "id": "A0A8V0YPC3", "url": "https://omabrowser.org/oma/group/A0A8V0YPC3/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q54CN9-1", "protein_name": "Peptidase A22B family protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEAVIESFKNLKMDLTIPDNGLLIAYISIWIMAIVPIYIGSFLSLKETKSESMSMSDAYTFPIIGSVFLFGLYLCFKYFDKDLINLILSYYFLLIGAIAMTNVLSSLFKYMFVGSSGSGKNKKQNEVKPLISFKIPAIKFITDAKDVKIDIYDIVSFIFAIGFSLWYIKTKHWIANNIFGLTFSIQGISFISLTEYSVGVMLLVGLFFYDIFWVFGTDVMVTVAKSFDAPIKLLFPKDIFADVYQFSMLGLGDIVLPGIFIALLLRFDRHIHQESRSKGPMKKTYFNSTLIAYALGLFTTIFVMHTFKAAQPALLYLVPFCVGSSMIVSAIKGQFKKLLWSNLDTAKDNTKKTN", "length": 354 }, "evidence": [ { "id": "A0A8V0YPC3", "url": "https://omabrowser.org/oma/group/A0A8V0YPC3/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q8TCT9-1", "protein_name": "Signal peptide peptidase", "gene_name": "HM13", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDSALSDPHNGSAEAGGPTNSTTRPPSTPEGIALAYGSLLLMALLPIFFGALRSVRCARGKNASDMPETITSRDAARFPIIASCTLLGLYLFFKIFSQEYINLLLSMYFFVLGILALSHTISPFMNKFFPASFPNRQYQLLFTQGSGENKEEIINYEFDTKDLVCLGLSSIVGVWYLLRKHWIANNLFGLAFSLNGVELLHLNNVSTGCILLGGLFIYDVFWVFGTNVMVTVAKSFEAPIKLVFPQDLLEKGLEANNFAMLGLGDVVIPGIFIALLLRFDISLKKNTHTYFYTSFAAYIFGLGLTIFIMHIFKHAQPALLYLVPACIGFPVLVALAKGEVTEMFSYEESNPKDPAAVTESKEGTEASASKGLEKKEK", "length": 377 }, "evidence": [ { "id": "A0A8V0YPC3", "url": "https://omabrowser.org/oma/group/A0A8V0YPC3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9D8V0-1", "protein_name": "Signal peptide peptidase", "gene_name": "Hm13", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDSAVSDPHNGSAEAGTPANGTTRPPSTPEGIALAYGSLLLMALLPIFFGALRSVRCARGKSSSDMPETITSRDAARFPIIASCTLLGLYLFFKIFSQEYINLLLSMYFFVLGILALSHTISPFMNKFFPANFPNRQYQLLFTQGSGENKEEIINYEFDTKDLVCLGLSSVVGVWYLLRKHWIANNLFGLAFSLNGVELLHLNNVSTGCILLGGLFIYDIFWVFGTNVMVTVAKSFEAPIKLVFPQDLLEKGLEADNFAMLGLGDIVIPGIFIALLLRFDISLKKNTHTYFYTSFAAYIFGLGLTIFIMHIFKHAQPALLYLVPACIGFPVLVALAKGEVAEMFSYEESNPKDPAAETESKEESTEASASKRLEKKEK", "length": 378 }, "evidence": [ { "id": "A0A8V0YPC3", "url": "https://omabrowser.org/oma/group/A0A8V0YPC3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VPQ7-1", "protein_name": "Signal peptide peptidase", "gene_name": "Spp", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MAEEVIGTVKEVLKGIIENVNAPKNESAPGEKKPSTPEGMAVAYSSLVVMAMLPIIFGSIRSVKLHKLKKSTGEKADTMTKKDAMYFPLIASAALFGLYLFFKIFQKVHINYLLTGYFFVLGVIALAHLLSPVINSLMPAAVPKVPFHILFTKGEGKHKEDIVNYKFSTHDIVCLVISSAIGVWYLLKKHWIANNLFGLAFAINGVEMLHLNNFVTGVILLSGLFFYDIFWVFGTNVMVTVAKSFEAPIKLVFPQDLIENGLNASNFAMLGLGDIVIPGIFIALLLRFDDSKKRKTRIYFYSTLIAYFLGLLATIFVMHVFKHAQPALLYLVPACMGTPLLVALIRGELKVLFAYEDHPEEKPEKKEKKEKDEGVSSSGSKKKESKKGK", "length": 389 }, "evidence": [ { "id": "A0A8V0YPC3", "url": "https://omabrowser.org/oma/group/A0A8V0YPC3/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPC3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPC3" } ], "pmid": "" }, { "name": "cytoplasmic side of endoplasmic reticulum membrane", "id": "GO:0098554", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098554", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPC3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPC3" } ], "pmid": "" }, { "name": "rough endoplasmic reticulum", "id": "GO:0005791", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005791", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPC3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPC3" } ], "pmid": "" }, { "name": "Derlin-1 retrotranslocation complex", "id": "GO:0036513", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036513", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPC3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPC3" } ], "pmid": "" }, { "name": "lumenal side of endoplasmic reticulum membrane", "id": "GO:0098553", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098553", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPC3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPC3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "aspartic endopeptidase activity, intramembrane cleaving", "id": "GO:0042500", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042500", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPC3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPC3" } ], "pmid": "" }, { "name": "protein homodimerization activity", "id": "GO:0042803", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042803", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPC3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPC3" } ], "pmid": "" }, { "name": "ubiquitin protein ligase binding", "id": "GO:0031625", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031625", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPC3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPC3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "membrane protein proteolysis involved in retrograde protein transport, ER to cytosol", 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protein 4", "type": "synonym", "evidence": [ { "id": "NP_001025965", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025965" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ720687.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA103992290, SAMEA103992323 [ECO:0006172] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000020.1. On Sep 23, 2021 this sequence version replaced NP_001025965.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001025965", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025965" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPK3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPK3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SETD4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPK3", "locus": { "chromosome": "1", "start_pos": 106654936, "end_pos": 106665201, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012925", "url": "https://www.ensembl.org/id/ENSGALG00010012925" } ] } } ], "crossref": [ { "id": "A0A8V0YPK3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YPK3", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd19177", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd19177", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "418511", "url": "https://www.ncbi.nlm.nih.gov/gene/418511", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001214", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001214", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015353", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015353", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016852", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016852", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036464", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036464", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044429", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044429", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046341", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046341", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050600", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050600", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:418511", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418511", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "ISHMKDE", "url": "https://omabrowser.org/oma/group/ISHMKDE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YGR2", "url": "https://www.orthodb.org/?gene=A0A8V0YGR2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YPK3", "url": "https://www.orthodb.org/?gene=A0A8V0YPK3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13271", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13271", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13271:SF151", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13271:SF151", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00856", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00856", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF09273", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09273", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001025965", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025965", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "60264", "url": "https://www.rhea-db.org/rhea/60264", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "60268", "url": "https://www.rhea-db.org/rhea/60268", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "60344", "url": "https://www.rhea-db.org/rhea/60344", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "60348", "url": "https://www.rhea-db.org/rhea/60348", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "61992", "url": "https://www.rhea-db.org/rhea/61992", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YGR2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGR2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YGR2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGR2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YPK3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPK3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YPK3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPK3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKKSRGRTSRKRRRKRLQKFMYGVNCSHKLEYIKLKKWLKDRGFGDSSLRPAQFWGTGRGLMTTKALQAGELVISLPEKCLVTTTTVLNSCLGEYIMKWKPPVSPLIALCTFLIAEKHAGERSLWKPYLDVLPKTYSCPVCLEQDVVQLLPEPLRKQAQEQRTAVHELYMSSKAFFSSLQSLFAENTATIFNYSALEWAWCTINTRTIYMKHSQRECFSLEPDVYALAPYLDLLNHSPNVQVKAAFNEQSRNYEIQTNSQCKKHEEVFICYGPHDNQRLLLEYGFVAVDNPHSSVYVSSDTLLKYFPPLDKQKNAKLSILKDHDLLENLTFGWDGPSWRLLTALKVLSLGGDEFTCWRRALLGDVISARNEQQALNITTKICHFLIEETQHVLLQISQMKRDKENLKEQLTLVEALRLEDLKILQKSAEILCNLNVTTI", "length": 439, "header": "tr|A0A8V0YPK3-1|A0A8V0YPK3_CHICK Isoform 1 of SET domain-containing protein 4 OS=Gallus gallus OX=9031 GN=SETD4 PE=3 SV=1 CANONICAL=A0A8V0YPK3-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YGR2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPK3/entry#A0A8V0YGR2-1", "sequence": { "sequence": "MKKSRGRTSRKRRRKRLQKFMYGVNCSHKLEYIKLKKWLKDRGFGDSSLRPAQFWGTGRGLMTTKALQAGELVISLPEKCLVTTTTVLNSCLGEYIMKWKPPVSPLIALCTFLIAEKHAGERSLWKPYLDVLPKTYSCPVCLEQDVVQLLPEPLRKQAQEQRTAVHELYMSSKAFFSSLQSLFAENTATIFNYSALEWAWCTINTRTIYMKHSQRECFSLEPDVYALAPYLDLLNHSPNVQVKAAFNEQSRNYEIQTNSQCKKHEEVFICYGPHDNQRLLLEYGFVAVDNPHSSVYVSSDTLLKYFPPLDKQKNAKLSILKDHDLLDTCWRRALLGDVISARNEQQALNITTKICHFLIEETQHVLLQISQMKRDKENLKEQLTLVEALRLEDLKILQKSAEILCNLNVTTI", "length": 412, "header": "tr|A0A8V0YGR2-1|A0A8V0YPK3_CHICK Computationally mapped isoform of SET domain-containing protein 4 OS=Gallus gallus OX=9031 GN=SETD4 PE=3 SV=1 CANONICAL=A0A8V0YPK3-1" }, "locus": { "chromosome": "1", "start_pos": 106664210, "end_pos": 106656084, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031071.1", "url": "https://www.ensembl.org/id/ENSGALT00010031071.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018066.1", "url": "https://www.ensembl.org/id/ENSGALP00010018066.1" } ] } }, { "isoform_ac": "A0A8V0YPK3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPK3/entry#A0A8V0YPK3-1", "sequence": { "sequence": "MKKSRGRTSRKRRRKRLQKFMYGVNCSHKLEYIKLKKWLKDRGFGDSSLRPAQFWGTGRGLMTTKALQAGELVISLPEKCLVTTTTVLNSCLGEYIMKWKPPVSPLIALCTFLIAEKHAGERSLWKPYLDVLPKTYSCPVCLEQDVVQLLPEPLRKQAQEQRTAVHELYMSSKAFFSSLQSLFAENTATIFNYSALEWAWCTINTRTIYMKHSQRECFSLEPDVYALAPYLDLLNHSPNVQVKAAFNEQSRNYEIQTNSQCKKHEEVFICYGPHDNQRLLLEYGFVAVDNPHSSVYVSSDTLLKYFPPLDKQKNAKLSILKDHDLLENLTFGWDGPSWRLLTALKVLSLGGDEFTCWRRALLGDVISARNEQQALNITTKICHFLIEETQHVLLQISQMKRDKENLKEQLTLVEALRLEDLKILQKSAEILCNLNVTTI", "length": 439, "header": "tr|A0A8V0YPK3-1|A0A8V0YPK3_CHICK Isoform 1 of SET domain-containing protein 4 OS=Gallus gallus OX=9031 GN=SETD4 PE=3 SV=1 CANONICAL=A0A8V0YPK3-1" }, "locus": { "chromosome": "1", "start_pos": 106664210, "end_pos": 106656084, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031085.1", "url": "https://www.ensembl.org/id/ENSGALT00010031085.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018079.1", "url": "https://www.ensembl.org/id/ENSGALP00010018079.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "gga:418511", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418511", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "E1B906-1", "protein_name": "SET domain-containing protein 4", "gene_name": "SETD4", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MKNGGGRTSRIRRRKLFTSSESRGVNESYKPEFIELKKWLKDRRFEDTTLIPAHFPGTGRGLMSKTSLQEGQTIISLPESCLLTTDTVIRSYLGAYIAKWQPPPSPLLALCTFLVSEKHAGDRSPWKPYLEVLPKAYTCPVCLEPEVVNLLPNPLKTKAWEQRSHVWEFFSSSRGFFSSLQPLFSEAVETIFSYRALRWAWCAVNTRAVYMKRPPLLCLSPEPDTCALAPYLDLLNHSPDVQVKAAFNEETRCYEIRTATRCGKHKEVFICYGPHDNHRLLLEYGFVCVSNPHACVYVSKDILVKYLPSTAKQMNKKISILEDHDFTENLTFGWDGPSWRLLTALKLLCLEAEEFTCWKKVLLGEIISDTNEKASLDVAQKICHYFIEETHAVLRKVSRMKDEEVALMNQLTLVETLRTEELKILQASAKALTTLQTAFS", "length": 440 }, "evidence": [ { "id": "A0A8V0YPK3", "url": "https://omabrowser.org/oma/group/A0A8V0YPK3/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "I3LLN1-1", "protein_name": "SET domain-containing protein 4", "gene_name": "SETD4", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MKKGGGRTSRIRRRKRFGKAESRGVNESYKPEFIELKKWLKDRNFEDTNLIPARFPGTGRGLMSKTSLQEGQLVIALPESCLLTTDTVLRSYLGPYIAKWQPPPSPLLALCTFLVSEKHAGDQSPWKPYLEVLPKTYTCPVCLEPEVVNLLPGPLKSKAREQRTRVWEFFSSSRDFFSSLQPLFPEAVESIFSYSALLWAWCTVNTRAVYMKQRPRQCFSTEPDTCALAPYLDLLNHSPAVQVKAAFNEESRCYEIRTGTSCRKHEEVFICYGPHGSHRLLLEYGFVSPRNPHACVYVPKDILVKYLPSTDKQMNKKISILKDHDFIENLTFGWDGPSWRLLTALKLLCLGAEDFTCWKKVLLGEVISDAHEKTSLDIAQKICHYFIEETNAMLQKISHMKDEDVALINQLTLVETLRTEELKILQASTEILAGLQTAFM", "length": 440 }, "evidence": [ { "id": "A0A8V0YPK3", "url": "https://omabrowser.org/oma/group/A0A8V0YPK3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P58467-1", "protein_name": "SET domain-containing protein 4", "gene_name": "Setd4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MQRRRGRTERARKRRRRSSGSRAVNESYRSEFIELRKWLKERKFEDTDLVPASFPGTGRGLMSKASLQEGQVMISLPESCLLTTDTVIRSSLGPYIKKWKPPVSPLLALCTFLVSEKHAGCRSLWKSYLDILPKSYTCPVCLEPEVVDLLPSPLKAKAEEQRARVQDLFTSARGFFSTLQPLFAEPVDSVFSYRAFLWAWCTVNTRAVYLRSRRQECLSAEPDTCALAPFLDLLNHSPHVQVKAAFNEKTRCYEIRTASRCRKHQEVFICYGPHDNQRLLLEYGFVSVRNPHACVPVSADMLVKFLPAADKQLHRKITILKDHGFTGNLTFGWDGPSWRLLTALKLLCLEAERFTSWKKVLLGEVISDTNEKTSLGVAQKICSDVIEETHAVLRKVSDMKEGTVSLRSQLSLVEALRMEELRILQASAEILSGLLAPFS", "length": 439 }, "evidence": [ { "id": "A0A8V0YPK3", "url": "https://omabrowser.org/oma/group/A0A8V0YPK3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9NVD3-1", "protein_name": "SET domain-containing protein 4", "gene_name": "SETD4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MQKGKGRTSRIRRRKLCGSSESRGVNESHKSEFIELRKWLKARKFQDSNLAPACFPGTGRGLMSQTSLQEGQMIISLPESCLLTTDTVIRSYLGAYITKWKPPPSPLLALCTFLVSEKHAGHRSLWKPYLEILPKAYTCPVCLEPEVVNLLPKSLKAKAEEQRAHVQEFFASSRDFFSSLQPLFAEAVDSIFSYSALLWAWCTVNTRAVYLRPRQRECLSAEPDTCALAPYLDLLNHSPHVQVKAAFNEETHSYEIRTTSRWRKHEEVFICYGPHDNQRLFLEYGFVSVHNPHACVYVSREILVKYLPSTDKQMDKKISILKDHGYIENLTFGWDGPSWRLLTALKLLCLEAEKFTCWKKVLLGEVISDTNEKTSLDIAQKICYYFIEETNAVLQKVSHMKDEKEALINQLTLVESLWTEELKILRASAETLHSLQTAFT", "length": 440 }, "evidence": [ { "id": "A0A8V0YPK3", "url": "https://omabrowser.org/oma/group/A0A8V0YPK3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 6, "go_terms": [ { "name": "protein-lysine N-methyltransferase activity", "id": "GO:0016279", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016279", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPK3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPK3" } ], "pmid": "" }, { "name": "transcription coactivator activity", "id": "GO:0003713", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003713", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPK3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPK3" } ], "pmid": "" }, { "name": "histone H3K4 methyltransferase activity", "id": "GO:0042800", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042800", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPK3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPK3" } ], "pmid": "" }, { "name": "histone H3K36 methyltransferase activity", "id": "GO:0046975", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046975", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPK3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPK3" } ], "pmid": "" }, { "name": "histone H4K20 methyltransferase activity", "id": "GO:0042799", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042799", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPK3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPK3" } ], "pmid": "" }, { "name": "histone H3K4 monomethyltransferase activity", "id": "GO:0140945", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140945", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPK3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPK3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPK3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPK3" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPK3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPK3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 8, "go_terms": [ { "name": "chromatin remodeling", "id": "GO:0006338", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006338", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPK3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPK3" } ], "pmid": "" }, { "name": "inflammatory response", "id": "GO:0006954", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006954", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPK3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPK3" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPK3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPK3" } ], "pmid": "" }, { "name": "positive regulation of interleukin-6 production", "id": "GO:0032755", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032755", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPK3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPK3" } ], "pmid": "" }, { "name": "positive regulation of inflammatory response", "id": "GO:0050729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050729", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPK3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPK3" } ], "pmid": "" }, { "name": "positive regulation of tumor necrosis factor production", "id": "GO:0032760", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032760", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPK3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPK3" } ], "pmid": "" }, { "name": "methylation", "id": "GO:0032259", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032259", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPK3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPK3" } ], "pmid": "" }, { "name": "regulation of cell proliferation in bone marrow", "id": "GO:0071863", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071863", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPK3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPK3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 192, "end_pos": 194, "annotation": "n_glycosylation_sequon" }, { "start_pos": 235, "end_pos": 237, "annotation": "n_glycosylation_sequon" }, { "start_pos": 25, "end_pos": 27, "annotation": "n_glycosylation_sequon" }, { "start_pos": 328, "end_pos": 330, "annotation": "n_glycosylation_sequon" }, { "start_pos": 376, "end_pos": 378, "annotation": "n_glycosylation_sequon" }, { "start_pos": 435, "end_pos": 437, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "60264", "name": "", "equation": "L-lysyl(4)-[histone H3] + S-adenosyl-L-methionine = N(6)-methyl-L-lysyl(4)-[histone H3] + S-adenosyl-L-homocysteine + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0Y4K0-1", "A0A8V0ZWT3-1", "A0A8V0ZTY1-1", "A0A8V1AA15-1", "A0A8V0YPK3-1" ], "evidence": [ { "id": "60264", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/60264" } ] }, { "id": "60268", "name": "", "equation": "N(6)-methyl-L-lysyl(4)-[histone H3] + S-adenosyl-L-methionine = N(6),N(6)-dimethyl-L-lysyl(4)-[histone H3] + S-adenosyl-L-homocysteine + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0ZWT3-1", "A0A8V0YPK3-1" ], "evidence": [ { "id": "60268", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/60268" } ] }, { "id": "60344", "name": "", "equation": "L-lysyl(20)-[histone H4] + S-adenosyl-L-methionine = N(6)-methyl-L-lysyl(20)-[histone H4] + S-adenosyl-L-homocysteine + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0ZUS5-1", "A0A8V0ZYQ2-1", "A0A8V0XA22-1", "A0A8V0YPK3-1" ], "evidence": [ { "id": "60344", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/60344" } ] }, { "id": "60348", "name": "", "equation": "N(6)-methyl-L-lysyl(20)-[histone H4] + S-adenosyl-L-methionine = N(6),N(6)-dimethyl-L-lysyl(20)-[histone H4] + S-adenosyl-L-homocysteine + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0ZYQ2-1", "A0A8V0YPK3-1" ], "evidence": [ { "id": "60348", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/60348" } ] }, { "id": "61992", "name": "", "equation": "N(6),N(6)-dimethyl-L-lysyl(20)-[histone H4] + S-adenosyl-L-methionine = N(6),N(6),N(6)-trimethyl-L-lysyl(20)-[histone H4] + S-adenosyl-L-homocysteine + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0ZYQ2-1", "A0A8V0YPK3-1" ], "evidence": [ { "id": "61992", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/61992" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A8V0XA22", "gene_name": "PRDM6", "activity": [ { "ec_number": "2.1.1.361", "activity": "L-lysyl(20)-[histone H4] + S-adenosyl-L-methionine = N(6)-methyl-L-lysyl(20)-[histone H4] + S-adenosyl-L-homocysteine + H(+).", "evidence": [ { "id": "A0A8V0XA22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XA22" } ] }, { "ec_number": "2.1.1.361", "activity": "", "evidence": [ { "id": "A0A8V0XA22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XA22" } ] } ] }, { "uniprot_ac": "A0A8V0Y4K0", "gene_name": "SETD7", "activity": [ { "ec_number": "2.1.1.364", "activity": "L-lysyl(4)-[histone H3] + S-adenosyl-L-methionine = N(6)-methyl-L-lysyl(4)-[histone H3] + S-adenosyl-L-homocysteine + H(+).", "evidence": [ { "id": "A0A8V0Y4K0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y4K0" } ] }, { "ec_number": "2.1.1.364", "activity": "", "evidence": [ { "id": "A0A8V0Y4K0", "database": "UniProtKB", "url": 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gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YN44", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN44" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CTBPL", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN44", "locus": { "chromosome": "13", "start_pos": 17760050, "end_pos": 17745170, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010014179", "url": "https://www.ensembl.org/id/ENSGALG00010014179" } ] } } ], "crossref": [ { "id": "A0A8V0YN44", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YN44", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd05299", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05299", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "416354", "url": "https://www.ncbi.nlm.nih.gov/gene/416354", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006139", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006139", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006140", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006140", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029752", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029752", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029753", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029753", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036291", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036291", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043322", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043322", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051638", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051638", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PMDRHKV", "url": "https://omabrowser.org/oma/group/PMDRHKV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YGR7", "url": "https://www.orthodb.org/?gene=A0A8V0YGR7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46029", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46029", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46029:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46029:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00389", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00389", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02826", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02826", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YGR7", "url": 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"MDRHKVKRQRLDRICEGIRPPAVNGPMPSRPLVALLDGRDCTVEMPILKDVATVAFCDAQSTQEIHEKVLNEAVGALMYHTITLSRQDLEKFKALRVIVRIGSGYDNVDIKSAAELGIAVCNIPSSSVEETADSTLCHILNLYRRVTWLHQAMREGNRASSVEQIREVAGGAVRIRGETLGIIGLGRVGQAVALRAKSFGFNVIFYDPYLPDGVERSLGLQRVGTLQDLLMHSDCITLHCSLNEHNHHLINDFTIKQMRQGCFLVNTARGGLVDEKALAQALKEGRIRGTALDVHESEPFSFAQGPLKDAPNVICTPHTAWYSEQASIESREDAAKEIRRAITGVPTGHIPDALRNCVNKEYLLLAAQWSGIDPASVHPELNGAAAYRFPPGVVGVTTPGLPEPPVVEGIVAHGIPSVSHSAPRTPSPGETSKLDADREIPADQ", "length": 444, "header": "tr|A0A8V0YN44-1|A0A8V0YN44_CHICK Isoform 1 of C-terminal binding protein-like OS=Gallus gallus OX=9031 GN=CTBPL PE=1 SV=1 CANONICAL=A0A8V0YN44-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YGR7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN44/entry#A0A8V0YGR7-1", "sequence": { "sequence": "MFTLHLINSVTYFRVYQERPRYEPLPHGRTLDYSRAFVSRCLYLFRPWQQGIRPPAVNGPMPSRPLVALLDGRDCTVEMPILKDVATVAFCDAQSTQEIHEKVLNEAVGALMYHTITLSRQDLEKFKALRVIVRIGSGYDNVDIKSAAELGIAVCNIPSSSVEETADSTLCHILNLYRRVTWLHQAMREGNRASSVEQIREVAGGAVRIRGETLGIIGLGRVGQAVALRAKSFGFNVIFYDPYLPDGVERSLGLQRVGTLQDLLMHSDCITLHCSLNEHNHHLINDFTIKQMRQGCFLVNTARGGLVDEKALAQALKEGRIRGTALDVHESEPFSFAQGPLKDAPNVICTPHTAWYSEQASIESREDAAKEIRRAITGHIPDALRNCVNKEYLLLAAQWSGIDPASVHPELNGAAAYRFPPGVVGVTTPGLPEPPVVEGIVAHGIPSVSHSAPRTPSPGETSKLDADREIPADQ", "length": 474, "header": "tr|A0A8V0YGR7-1|A0A8V0YN44_CHICK Computationally mapped isoform of C-terminal binding protein-like OS=Gallus gallus OX=9031 GN=CTBPL PE=1 SV=1 CANONICAL=A0A8V0YN44-1" }, "locus": { "chromosome": "13", "start_pos": 17756650, "end_pos": 17745369, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034153.1", "url": "https://www.ensembl.org/id/ENSGALT00010034153.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020065.1", "url": "https://www.ensembl.org/id/ENSGALP00010020065.1" } ] } }, { "isoform_ac": "A0A8V0YMX2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN44/entry#A0A8V0YMX2-1", "sequence": { "sequence": "MCLQVYRIRPPAVNGPMPSRPLVALLDGRDCTVEMPILKDVATVAFCDAQSTQEIHEKVLNEAVGALMYHTITLSRQDLEKFKALRVIVRIGSGYDNVDIKSAAELGIAVCNIPSSSVEETADSTLCHILNLYRRVTWLHQAMREGNRASSVEQIREVAGGAVRIRGETLGIIGLGRVGQAVALRAKSFGFNVIFYDPYLPDGVERSLGLQRVGTLQDLLMHSDCITLHCSLNEHNHHLINDFTIKQMRQGCFLVNTARGGLVDEKALAQALKEGRIRGTALDVHESEPFSFAQGPLKDAPNVICTPHTAWYSEQASIESREDAAKEIRRAITGHIPDALRNCVNKEYLLLAAQWSGIDPASVHPELNGAAAYRFPPGVVGVTTPGLPEPPVVEGIVAHGIPSVSHSAPRTPSPGETSKLDADREIPADQ", "length": 430, "header": "tr|A0A8V0YMX2-1|A0A8V0YMX2_CHICK Computationally mapped isoform of C-terminal binding protein-like OS=Gallus gallus OX=9031 GN=CTBPL PE=1 SV=1 CANONICAL=A0A8V0YN44-1" }, "locus": { "chromosome": "13", "start_pos": 17756650, "end_pos": 17749353, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034141.1", "url": "https://www.ensembl.org/id/ENSGALT00010034141.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020059.1", "url": "https://www.ensembl.org/id/ENSGALP00010020059.1" } ] } }, { "isoform_ac": "A0A8V0YN44-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN44/entry#A0A8V0YN44-1", "sequence": { "sequence": "MDRHKVKRQRLDRICEGIRPPAVNGPMPSRPLVALLDGRDCTVEMPILKDVATVAFCDAQSTQEIHEKVLNEAVGALMYHTITLSRQDLEKFKALRVIVRIGSGYDNVDIKSAAELGIAVCNIPSSSVEETADSTLCHILNLYRRVTWLHQAMREGNRASSVEQIREVAGGAVRIRGETLGIIGLGRVGQAVALRAKSFGFNVIFYDPYLPDGVERSLGLQRVGTLQDLLMHSDCITLHCSLNEHNHHLINDFTIKQMRQGCFLVNTARGGLVDEKALAQALKEGRIRGTALDVHESEPFSFAQGPLKDAPNVICTPHTAWYSEQASIESREDAAKEIRRAITGVPTGHIPDALRNCVNKEYLLLAAQWSGIDPASVHPELNGAAAYRFPPGVVGVTTPGLPEPPVVEGIVAHGIPSVSHSAPRTPSPGETSKLDADREIPADQ", "length": 444, "header": "tr|A0A8V0YN44-1|A0A8V0YN44_CHICK Isoform 1 of C-terminal binding protein-like OS=Gallus gallus OX=9031 GN=CTBPL PE=1 SV=1 CANONICAL=A0A8V0YN44-1" }, "locus": { "chromosome": "13", "start_pos": 17756650, "end_pos": 17748919, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034146.1", "url": "https://www.ensembl.org/id/ENSGALT00010034146.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020062.1", "url": "https://www.ensembl.org/id/ENSGALP00010020062.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 6, "go_terms": [ { "name": "transcription coactivator activity", "id": "GO:0003713", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003713", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YN44", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN44" } ], "pmid": "" }, { "name": "transcription corepressor activity", "id": "GO:0003714", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003714", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YN44", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN44" } ], "pmid": "" }, { "name": "NAD binding", "id": "GO:0051287", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051287", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YN44", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN44" } ], "pmid": "" }, { "name": "oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor", "id": "GO:0016616", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016616", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YN44", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN44" } ], "pmid": "" }, { "name": "transcription coregulator binding", "id": "GO:0001221", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001221", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YN44", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN44" } ], "pmid": "" }, { "name": "DNA-binding transcription factor binding", "id": "GO:0140297", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140297", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YN44", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN44" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YN44", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN44" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YN44", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN44" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YN44", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN44" }, { "id": "PF02826", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02826" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding", "eco_id": "ECO_0000259", "start_pos": 138, "end_pos": 320, "start_aa": "His", "end_aa": "Ala", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0YN44", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN44" }, { "id": "PF00389", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00389" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "D-isomer specific 2-hydroxyacid dehydrogenase catalytic", "eco_id": "ECO_0000259", "start_pos": 41, "end_pos": 346, "start_aa": "Cys", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YPS0-1", "uniprot_ac": "A0A8V0YPS0", "uniprot_id": "A0A8V0YPS0_CHICK", "mass": { "chemical_mass": 57322.0, "monoisotopic_mass": 57322.0 }, "refseq": {}, "gene_names": [ { "name": "TMEM184B", "type": "recommended", "evidence": [ { "id": "A0A8V0YPS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPS0" } ] } ], "protein_names": [ { "name": "Transmembrane protein 184B", "type": "synonym", "evidence": [ { "id": "A0A8V0YPS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPS0/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPS0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPS0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TMEM184B", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPS0", "locus": { "chromosome": "1", "start_pos": 51015298, "end_pos": 50989851, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012986", "url": "https://www.ensembl.org/id/ENSGALG00010012986" } ] } } ], "crossref": [ { "id": "A0A8V0YPS0", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YPS0", "database": "AlphaFoldDB", "categories": [] }, { "id": "418027", "url": "https://www.ncbi.nlm.nih.gov/gene/418027", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR005178", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005178", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YBK0", "url": "https://www.orthodb.org/?gene=A0A8V0YBK0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YGZ8", "url": "https://www.orthodb.org/?gene=A0A8V0YGZ8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YHZ0", "url": "https://www.orthodb.org/?gene=A0A8V0YHZ0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YJY0", "url": "https://www.orthodb.org/?gene=A0A8V0YJY0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YJY5", "url": "https://www.orthodb.org/?gene=A0A8V0YJY5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YJZ0", "url": "https://www.orthodb.org/?gene=A0A8V0YJZ0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YPS0", "url": "https://www.orthodb.org/?gene=A0A8V0YPS0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YPS7", "url": "https://www.orthodb.org/?gene=A0A8V0YPS7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23423", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23423", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03619", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03619", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YBK0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBK0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YBK0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBK0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YGZ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGZ8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YGZ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGZ8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHZ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHZ0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHZ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHZ0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJY0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJY0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJY0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJY0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJY5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJY5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJY5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJY5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJZ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJZ0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJZ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJZ0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YPS0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPS0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YPS0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPS0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YPS7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPS7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YPS7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPS7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKVFFASTCARSLLFTVLSLFLVEEAAVLVLGTEGLCFQKSQGWQSVSDRERLRCCSPVAAGRMGAAGERQNCSCAGWSPFPVLSLGQFFSNPRWNLTLKGTMMVMTDVTAAPRLGSAATTPAVAPNFSWLPEDGSPTAVEQPIFLMTTAAQAISGFFVWTALLITCHQIYMHLRCYSCPNEQRYIVRILFIVPIYAFDSWLSLLFFTNDQYYVYFGTVRDCYEAFVIYNFLSLCYEYLGGESSIMSEIRGKPIESSCVYGTCCLWGKTYSIGFLRFCKQATLQFCVVKPLMAISTVILQAFDKYQDGDFDVTSGYLYVTIIYNISVSLALYALFLFYFATRELLSPYSPVLKFFMVKSVIFLSFWQGMLLAILEKCGAIPKIHSANVSVGEGTVAAGYQDFIICVEMFFAAIALRHAFTYKVYADKRLDAQGRCAPMKSISSSLKETMNPHDIVQDAIHNFSPAYQQYTQQSTLEHGPPWRNGSHVISRSHSCSGARDNEKTLLLSSDDEF", "length": 512, "header": "tr|A0A8V0YPS0-1|A0A8V0YPS0_CHICK Isoform 1 of Transmembrane protein 184B OS=Gallus gallus OX=9031 GN=TMEM184B PE=4 SV=1 CANONICAL=A0A8V0YPS0-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YBK0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPS0/entry#A0A8V0YBK0-1", "sequence": { "sequence": "MEVLSLGQFFSNPRWNLTLKGTMMVMTDVTAAPRLGSAATTPAVAPNFSWLPEDGSPTAVEQPIFLMTTAAQAISGFFVWTALLITCHQIYMHLRCYSCPNEQRYIVRILFIVPIYAFDSWLSLLFFTNDQYYVYFGTVRDCYEAFVIYNFLSLCYEYLGGESSIMSEIRGKPIESSCVYGTCCLWGKTYSIGFLRFCKQATLQFCVVKPLMAISTVILQAFDKYQDGDFDVTSGYLYVTIIYNISVSLALYALFLFYFATRELLSPYSPVLKFFMVKSVIFLSFWQGMLLAILEKCGAIPKIHSANVSVGEGTVAAGYQDFIICVEMFFAAIALRHAFTYKVYADKRLDAQGRCAPMKSISSSLKETMNPHDIVQDAIHNFSPAYQQYTQQSTLEHGPPWRNGSHVISRSHSCSGARDNEKTLLLSSDDEF", "length": 432, "header": "tr|A0A8V0YBK0-1|A0A8V0YBK0_CHICK Computationally mapped isoform of Transmembrane protein 184B OS=Gallus gallus OX=9031 GN=TMEM184B PE=4 SV=1 CANONICAL=A0A8V0YPS0-1" }, "locus": { "chromosome": "1", "start_pos": 51012987, "end_pos": 50998102, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031157.1", "url": "https://www.ensembl.org/id/ENSGALT00010031157.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018143.1", "url": "https://www.ensembl.org/id/ENSGALP00010018143.1" } ] } }, { "isoform_ac": "A0A8V0YGZ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPS0/entry#A0A8V0YGZ8-1", "sequence": { "sequence": "MSTAFHPWVLSLGQFFSNPRWNLTLKGTMMVMTDVTAAPRLGSAATTPAVAPNFSWLPEDGSPTAVEQPIFLMTTAAQAISGFFVWTALLITCHQIYMHLRCYSCPNEQRYIVRILFIVPIYAFDSWLSLLFFTNDQYYVYFGTVRDCYEAFVIYNFLSLCYEYLGGESSIMSEIRGKPIESSCVYGTCCLWGKTYSIGFLRFCKQATLQFCVVKPLMAISTVILQAFDKYQDGDFDVTSGYLYVTIIYNISVSLALYALFLFYFATRELLSPYSPVLKFFMVKSVIFLSFWQGMLLAILEKCGAIPKIHSANVSVGEGTVAAGYQDFIICVEMFFAAIALRHAFTYKVYADKRLDAQGRCAPMKSISSSLKETMNPHDIVQDAIHNFSPAYQQYTQQSTLEHGPPWRNGSHVISRSHSCSGARDNEKTLLLSSDDEF", "length": 438, "header": "tr|A0A8V0YGZ8-1|A0A8V0YPS0_CHICK Computationally mapped isoform of Transmembrane protein 184B OS=Gallus gallus OX=9031 GN=TMEM184B PE=4 SV=1 CANONICAL=A0A8V0YPS0-1" }, "locus": { "chromosome": "1", "start_pos": 51012987, "end_pos": 50999263, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031155.1", "url": "https://www.ensembl.org/id/ENSGALT00010031155.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018142.1", "url": "https://www.ensembl.org/id/ENSGALP00010018142.1" } ] } }, { "isoform_ac": "A0A8V0YHZ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPS0/entry#A0A8V0YHZ0-1", "sequence": { "sequence": "MMVMTDVTAAPRLGSAATTPAVAPNFSWLPEDGSPTAVEQPIFLMTTAAQAISGFFVWTALLITCHQIYMHLRCYSCPNEQRYIVRILFIVPIYAFDSWLSLLFFTNDQYYVYFGTVRDCYEAFVIYNFLSLCYEYLGGESSIMSEIRGKPIESSCVYGTCCLWGKTYSIGFLRFCKQATLQFCVVKPLMAISTVILQAFDKYQDGDFDVTSGYLYVTIIYNISVSLALYALFLFYFATRELLSPYSPVLKFFMVKSVIFLSFWQGMLLAILEKCGAIPKIHSANVSVGEGTVAAGYQDFIICVEMFFAAIALRHAFTYKVYADKRLDAQAVPSYGPYGRCAPMKSISSSLKETMNPHDIVQDAIHNFSPAYQQYTQQSTLEHGPPWRNGSHVISRSHSCSGARDNEKTLLLSSDDEF", "length": 418, "header": "tr|A0A8V0YHZ0-1|A0A8V0YPS0_CHICK Computationally mapped isoform of Transmembrane protein 184B OS=Gallus gallus OX=9031 GN=TMEM184B PE=4 SV=1 CANONICAL=A0A8V0YPS0-1" }, "locus": { "chromosome": "1", "start_pos": 51012987, "end_pos": 50999925, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031170.1", "url": "https://www.ensembl.org/id/ENSGALT00010031170.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018155.1", "url": "https://www.ensembl.org/id/ENSGALP00010018155.1" } ] } }, { "isoform_ac": "A0A8V0YJY0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPS0/entry#A0A8V0YJY0-1", "sequence": { "sequence": "MALGEVLSLGQFFSNPRWNLTLKGTMMVMTDVTAAPRLGSAATTPAVAPNFSWLPEDGSPTAVEQPIFLMTTAAQAISGFFVWTALLITCHQIYMHLRCYSCPNEQRYIVRILFIVPIYAFDSWLSLLFFTNDQYYVYFGTVRDCYEAFVIYNFLSLCYEYLGGESSIMSEIRGKPIESSCVYGTCCLWGKTYSIGFLRFCKQATLQFCVVKPLMAISTVILQAFDKYQDGDFDVTSGYLYVTIIYNISVSLALYALFLFYFATRELLSPYSPVLKFFMVKSVIFLSFWQGMLLAILEKCGAIPKIHSANVSVGEGTVAAGYQDFIICVEMFFAAIALRHAFTYKVYADKRLDAQGRCAPMKSISSSLKETMNPHDIVQDAIHNFSPAYQQYTQQSTLEHGPPWRNGSHVISRSHSCSGARDNEKTLLLSSDDEF", "length": 435, "header": "tr|A0A8V0YJY0-1|A0A8V0YPS0_CHICK Computationally mapped isoform of Transmembrane protein 184B OS=Gallus gallus OX=9031 GN=TMEM184B PE=4 SV=1 CANONICAL=A0A8V0YPS0-1" }, "locus": { "chromosome": "1", "start_pos": 51012987, "end_pos": 50999551, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031152.1", "url": "https://www.ensembl.org/id/ENSGALT00010031152.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018141.1", "url": "https://www.ensembl.org/id/ENSGALP00010018141.1" } ] } }, { "isoform_ac": "A0A8V0YJY5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPS0/entry#A0A8V0YJY5-1", "sequence": { "sequence": "MVSVESGVRRSSSSPCSHPGGPRSQVLSLGQFFSNPRWNLTLKGTMMVMTDVTAAPRLGSAATTPAVAPNFSWLPEDGSPTAVEQPIFLMTTAAQAISGFFVWTALLITCHQIYMHLRCYSCPNEQRYIVRILFIVPIYAFDSWLSLLFFTNDQYYVYFGTVRDCYEAFVIYNFLSLCYEYLGGESSIMSEIRGKPIESSCVYGTCCLWGKTYSIGFLRFCKQATLQFCVVKPLMAISTVILQAFDKYQDGDFDVTSGYLYVTIIYNISVSLALYALFLFYFATRELLSPYSPVLKFFMVKSVIFLSFWQGMLLAILEKCGAIPKIHSANVSVGEGTVAAGYQDFIICVEMFFAAIALRHAFTYKVYADKRLDAQGRCAPMKSISSSLKETMNPHDIVQDAIHNFSPAYQQYTQQSTLEHGPPWRNGSHVISRSHSCSGARDNEKTLLLSSDDEF", "length": 455, "header": "tr|A0A8V0YJY5-1|A0A8V0YPS0_CHICK Computationally mapped isoform of Transmembrane protein 184B OS=Gallus gallus OX=9031 GN=TMEM184B PE=4 SV=1 CANONICAL=A0A8V0YPS0-1" }, "locus": { "chromosome": "1", "start_pos": 51012987, "end_pos": 50996213, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031161.1", "url": "https://www.ensembl.org/id/ENSGALT00010031161.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018146.1", "url": "https://www.ensembl.org/id/ENSGALP00010018146.1" } ] } }, { "isoform_ac": "A0A8V0YJZ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPS0/entry#A0A8V0YJZ0-1", "sequence": { "sequence": "MLTYYNVLSLGQFFSNPRWNLTLKGTMMVMTDVTAAPRLGSAATTPAVAPNFSWLPEDGSPTAVEQPIFLMTTAAQAISGFFVWTALLITCHQIYMHLRCYSCPNEQRYIVRILFIVPIYAFDSWLSLLFFTNDQYYVYFGTVRDCYEAFVIYNFLSLCYEYLGGESSIMSEIRGKPIESSCVYGTCCLWGKTYSIGFLRFCKQATLQFCVVKPLMAISTVILQAFDKYQDGDFDVTSGYLYVTIIYNISVSLALYALFLFYFATRELLSPYSPVLKFFMVKSVIFLSFWQGMLLAILEKCGAIPKIHSANVSVGEGTVAAGYQDFIICVEMFFAAIALRHAFTYKVYADKRLDAQGRCAPMKSISSSLKETMNPHDIVQDAIHNFSPAYQQYTQQSTLEHGPPWRNGSHVISRSHSCSGARDNEKTLLLSSDDEF", "length": 436, "header": "tr|A0A8V0YJZ0-1|A0A8V0YPS0_CHICK Computationally mapped isoform of Transmembrane protein 184B OS=Gallus gallus OX=9031 GN=TMEM184B PE=4 SV=1 CANONICAL=A0A8V0YPS0-1" }, "locus": { "chromosome": "1", "start_pos": 51012987, "end_pos": 50994869, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031166.1", "url": "https://www.ensembl.org/id/ENSGALT00010031166.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018151.1", "url": "https://www.ensembl.org/id/ENSGALP00010018151.1" } ] } }, { "isoform_ac": "A0A8V0YPS0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPS0/entry#A0A8V0YPS0-1", "sequence": { "sequence": "MKVFFASTCARSLLFTVLSLFLVEEAAVLVLGTEGLCFQKSQGWQSVSDRERLRCCSPVAAGRMGAAGERQNCSCAGWSPFPVLSLGQFFSNPRWNLTLKGTMMVMTDVTAAPRLGSAATTPAVAPNFSWLPEDGSPTAVEQPIFLMTTAAQAISGFFVWTALLITCHQIYMHLRCYSCPNEQRYIVRILFIVPIYAFDSWLSLLFFTNDQYYVYFGTVRDCYEAFVIYNFLSLCYEYLGGESSIMSEIRGKPIESSCVYGTCCLWGKTYSIGFLRFCKQATLQFCVVKPLMAISTVILQAFDKYQDGDFDVTSGYLYVTIIYNISVSLALYALFLFYFATRELLSPYSPVLKFFMVKSVIFLSFWQGMLLAILEKCGAIPKIHSANVSVGEGTVAAGYQDFIICVEMFFAAIALRHAFTYKVYADKRLDAQGRCAPMKSISSSLKETMNPHDIVQDAIHNFSPAYQQYTQQSTLEHGPPWRNGSHVISRSHSCSGARDNEKTLLLSSDDEF", "length": 512, "header": "tr|A0A8V0YPS0-1|A0A8V0YPS0_CHICK Isoform 1 of Transmembrane protein 184B OS=Gallus gallus OX=9031 GN=TMEM184B PE=4 SV=1 CANONICAL=A0A8V0YPS0-1" }, "locus": { "chromosome": "1", "start_pos": 51012987, "end_pos": 50996687, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031159.1", "url": "https://www.ensembl.org/id/ENSGALT00010031159.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018144.1", "url": "https://www.ensembl.org/id/ENSGALP00010018144.1" } ] } }, { "isoform_ac": "A0A8V0YPS7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPS0/entry#A0A8V0YPS7-1", "sequence": { "sequence": "MVLSLGQFFSNPRWNLTLKGTMMVMTDVTAAPRLGSAATTPAVAPNFSWLPEDGSPTAVEQPIFLMTTAAQAISGFFVWTALLITCHQIYMHLRCYSCPNEQRYIVRILFIVPIYAFDSWLSLLFFTNDQYYVYFGTVRDCYEAFVIYNFLSLCYEYLGGESSIMSEIRGKPIESSCVYGTCCLWGKTYSIGFLRFCKQATLQFCVVKPLMAISTVILQAFDKYQDGDFDVTSGYLYVTIIYNISVSLALYALFLFYFATRELLSPYSPVLKFFMVKSVIFLSFWQGMLLAILEKCGAIPKIHSANVSVGEGTVAAGYQDFIICVEMFFAAIALRHAFTYKVYADKRLDAQGRCAPMKSISSSLKETMNPHDIVQDAIHNFSPAYQQYTQQSTLEHGPPWRNGSHVISRSHSCSGARDNEKTLLLSSDDEF", "length": 431, "header": "tr|A0A8V0YPS7-1|A0A8V0YPS7_CHICK Computationally mapped isoform of Transmembrane protein 184B OS=Gallus gallus OX=9031 GN=TMEM184B PE=4 SV=1 CANONICAL=A0A8V0YPS0-1" }, "locus": { "chromosome": "1", "start_pos": 51012987, "end_pos": 50996213, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031164.1", "url": "https://www.ensembl.org/id/ENSGALT00010031164.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018149.1", "url": "https://www.ensembl.org/id/ENSGALP00010018149.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPS0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPS0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "transmembrane transporter activity", "id": "GO:0022857", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022857", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPS0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPS0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 127, "end_pos": 129, "annotation": "n_glycosylation_sequon" }, { "start_pos": 324, "end_pos": 326, "annotation": "n_glycosylation_sequon" }, { "start_pos": 387, "end_pos": 389, "annotation": "n_glycosylation_sequon" }, { "start_pos": 461, "end_pos": 463, "annotation": "n_glycosylation_sequon" }, { "start_pos": 483, "end_pos": 485, "annotation": "n_glycosylation_sequon" }, { "start_pos": 72, "end_pos": 74, "annotation": "n_glycosylation_sequon" }, { "start_pos": 96, "end_pos": 98, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 127, "end_pos": 129 }, { "start_pos": 324, "end_pos": 326 }, { "start_pos": 387, "end_pos": 389 }, { "start_pos": 461, "end_pos": 463 }, { "start_pos": 483, "end_pos": 485 }, { "start_pos": 72, "end_pos": 74 }, { "start_pos": 96, "end_pos": 98 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YNF3-1", "uniprot_ac": "A0A8V0YNF3", "uniprot_id": "A0A8V0YNF3_CHICK", "mass": { "chemical_mass": 139667.0, "monoisotopic_mass": 139667.0 }, "refseq": {}, "gene_names": [ { "name": "ADNP", "type": "recommended", "evidence": [ { "id": "A0A8V0YNF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNF3" } ] } ], "protein_names": [ { "name": "Activity dependent neuroprotector homeobox", "type": "synonym", "evidence": [ { "id": "A0A8V0YNF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNF3/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNF3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNF3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ADNP", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNF3", "locus": { "chromosome": "20", "start_pos": 13770963, "end_pos": 13745450, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010014260", "url": "https://www.ensembl.org/id/ENSGALG00010014260" } ] } } ], "crossref": [ { "id": "A0A8V0YNF3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YNF3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000007989", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000007989", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00086", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00086", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "419350", "url": "https://www.ncbi.nlm.nih.gov/gene/419350", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001356", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001356", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009057", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009057", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038861", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038861", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045762", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045762", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PYCTFNG", "url": "https://omabrowser.org/oma/group/PYCTFNG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PL01", "url": "https://www.orthodb.org/?gene=A0A1D5PL01", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YH19", "url": "https://www.orthodb.org/?gene=A0A8V0YH19", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YNF3", "url": "https://www.orthodb.org/?gene=A0A8V0YNF3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YNF7", "url": "https://www.orthodb.org/?gene=A0A8V0YNF7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YNG2", "url": "https://www.orthodb.org/?gene=A0A8V0YNG2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15740", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15740", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15740:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15740:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00046", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00046", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF19627", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19627", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF26748", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF26748", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-9940465", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9940465", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A1D5PL01", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PL01", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PL01-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PL01-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YH19", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH19", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YH19-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH19-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YNF3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNF3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YNF3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNF3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YNF7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNF7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YNF7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNF7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YNG2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNG2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YNG2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNG2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLATFNQILCKWGSEKVQQQLMMPRKAFLSQKEKQARARERDMLKKRRRRQDYLKRSVDPQKNAETIKWHRDDEKRRENEQVKDKDIKKRWRQDERERRKNVDAMNWRREDEKRENERETMFQLPVNNLGSLRKARKTVKKILSDIGLEYCKEHIEDFKQFEPNDFYLKNTTWEDVGLWDPSLTKNQDYRTKPFCCSACPFSSKFFSAYKSHFRNVHSEDFENRILLNCPYCTFNADKKTLETHIKIFHAPNANTPSGGISTFKDKNKHDSLKPKQADSVEQAVYYCKKCTYRDPLYEIVRKHIYREHFQHVAAPYVAKGGEKSLNGAVPLSSSTREEGSIHCKRCLFMPKSYEALVQHVIEDHERIGYQVTAMIGHTNVVVPRSKPLMLIAPKPQDKKPMGLPQRMGPLSPGSVRSLSSQQMMNRLTIPKPTLNSAGVNMMSNVHLQQNNYGVKSVPPSYVGQPGGRLSLSGNAPVSIPQQSQTMKQFSSGNGRPYALGEQRSQASARYSLQSANSTSLSSAQLKQTSLSQSQAASRVLGQSGSKSPVAATGPSSVNTSSTQKWKICTICNELFPENVYSVHFEKEHKAEKVPAVANYIMKIHNFTSKCLYCNRYLPTDTLLNHMLIHGLSCPYCRSTFNDVEKMAAHMRMVHVDEEMGPKTDSTLTFDLTLQQGSLTNIHLLVTTYNLRDAPAESVAYHAQNTPPVPPKPQPKIQEKSDVPVKSSPQAAVPYKKDVGKTLCPLCFSILKGPISDALAHHLRERHQVIQTVHPVEKKLTYKCIHCLGVYTSNMTASTITLHLVHCRGVGKTQNGQDKGTSSSRLSQSAGVAPVKRTYEHMEFSLMKRRKMDDDDSPSAFEEKPEEPVVLALDPKGHEDDSYEARKTFLTKYFNKQPYPTRREIEKLAASLWLWKSDIASHFSNKRKKCVRDCEKYKPGVLLGFNMKELNKVKHEMDFDAEWLFENHDEKNSRVNVSKTVDKKINIEKDNESSSDSYENIEEEYNESSSPFGPHISDIGEKASPDSIAENPDDGISKEIIEENTLPSPEKSDQKQEESSKYEEMISAEEQTKLVGDVSDSEGYQDDQDDAVEWKDGASQSESGPGSQQVSDFEDNTSEVKPEVWTDESSQSEDAGSSKPTAETKGGGSESDEEQSKWKNRSYGKVEEFWAKDQSQWKNASEIEESLTNQQMEWQNSTIDSEDGDQFDSVTDGVADPMHSSLSGVELSSQQA", "length": 1231, "header": "tr|A0A8V0YNF3-1|A0A8V0YNF3_CHICK Isoform 1 of Activity dependent neuroprotector homeobox OS=Gallus gallus OX=9031 GN=ADNP PE=1 SV=1 CANONICAL=A0A8V0YNF3-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PL01-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNF3/entry#A0A1D5PL01-1", "sequence": { "sequence": "MSLRRPSTINFGETMFQLPVNNLGSLRKARKTVKKILSDIGLEYCKEHIEDFKQFEPNDFYLKNTTWEDVGLWDPSLTKNQDYRTKPFCCSACPFSSKFFSAYKSHFRNVHSEDFENRILLNCPYCTFNADKKTLETHIKIFHAPNANTPSGGISTFKDKNKHDSLKPKQADSVEQAVYYCKKCTYRDPLYEIVRKHIYREHFQHVAAPYVAKGGEKSLNGAVPLSSSTREEGSIHCKRCLFMPKSYEALVQHVIEDHERIGYQVTAMIGHTNVVVPRSKPLMLIAPKPQDKKPMGLPQRMGPLSPGSVRSLSSQQMMNRLTIPKPTLNSAGVNMMSNVHLQQNNYGVKSVPPSYVGQPGGRLSLSGNAPVSIPQQSQTMKQFSSGNGRPYALGEQRSQASARYSLQSANSTSLSSAQLKQTSLSQSQAASRVLGQSGSKSPVAATGPSSVNTSSTQKWKICTICNELFPENVYSVHFEKEHKAEKVPAVANYIMKIHNFTSKCLYCNRYLPTDTLLNHMLIHGLSCPYCRSTFNDVEKMAAHMRMVHVDEEMGPKTDSTLTFDLTLQQGSLTNIHLLVTTYNLRDAPAESVAYHAQNTPPVPPKPQPKIQEKSDVPVKSSPQAAVPYKKDVGKTLCPLCFSILKGPISDALAHHLRERHQVIQTVHPVEKKLTYKCIHCLGVYTSNMTASTITLHLVHCRGVGKTQNGQDKGTSSSRLSQSAGVAPVKRTYEHMEFSLMKRRKMDDDDSPSAFEEKPEEPVVLALDPKGHEDDSYEARKTFLTKYFNKQPYPTRREIEKLAASLWLWKSDIASHFSNKRKKCVRDCEKYKPGVLLGFNMKELNKVKHEMDFDAEWLFENHDEKNSRVNVSKTVDKKINIEKDNESSSDSYENIEEEYNESSSPFGPHISDIGEKASPDSIAENPDDGISKEIIEENTLPSPEKSDQKQEESSKYEEMISAEEQTKLVGDVSDSEGYQDDQDDAVEWKDGASQSESGPGSQQVSDFEDNTSEVKPEVWTDESSQSEDAGSSKPTAETKGGGSESDEEQSKWKNRSYGKVEEFWAKDQSQWKNASEIEESLTNQQMEWQNSTIDSEDGDQFDSVTDGVADPMHSSLSGVELSSQQA", "length": 1125, "header": "tr|A0A1D5PL01-1|A0A1D5PL01_CHICK Computationally mapped isoform of Activity dependent neuroprotector homeobox OS=Gallus gallus OX=9031 GN=ADNP PE=1 SV=1 CANONICAL=A0A8V0YNF3-1" }, "locus": { "chromosome": "20", "start_pos": 13769882, "end_pos": 13753492, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034341.1", "url": "https://www.ensembl.org/id/ENSGALT00010034341.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020169.1", "url": "https://www.ensembl.org/id/ENSGALP00010020169.1" } ] } }, { "isoform_ac": "A0A8V0YH19-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNF3/entry#A0A8V0YH19-1", "sequence": { "sequence": "MKGQPNVLIKETMFQLPVNNLGSLRKARKTVKKILSDIGLEYCKEHIEDFKQFEPNDFYLKNTTWEDVGLWDPSLTKNQDYRTKPFCCSACPFSSKFFSAYKSHFRNVHSEDFENRILLNCPYCTFNADKKTLETHIKIFHAPNANTPSGGISTFKDKNKHDSLKPKQADSVEQAVYYCKKCTYRDPLYEIVRKHIYREHFQHVAAPYVAKGGEKSLNGAVPLSSSTREEGSIHCKRCLFMPKSYEALVQHVIEDHERIGYQVTAMIGHTNVVVPRSKPLMLIAPKPQDKKPMGLPQRMGPLSPGSVRSLSSQQMMNRLTIPKPTLNSAGVNMMSNVHLQQNNYGVKSVPPSYVGQPGGRLSLSGNAPVSIPQQSQTMKQFSSGNGRPYALGEQRSQASARYSLQSANSTSLSSAQLKQTSLSQSQAASRVLGQSGSKSPVAATGPSSVNTSSTQKWKICTICNELFPENVYSVHFEKEHKAEKVPAVANYIMKIHNFTSKCLYCNRYLPTDTLLNHMLIHGLSCPYCRSTFNDVEKMAAHMRMVHVDEEMGPKTDSTLTFDLTLQQGSLTNIHLLVTTYNLRDAPAESVAYHAQNTPPVPPKPQPKIQEKSDVPVKSSPQAAVPYKKDVGKTLCPLCFSILKGPISDALAHHLRERHQVIQTVHPVEKKLTYKCIHCLGVYTSNMTASTITLHLVHCRGVGKTQNGQDKGTSSSRLSQSAGVAPVKRTYEHMEFSLMKRRKMDDDDSPSAFEEKPEEPVVLALDPKGHEDDSYEARKTFLTKYFNKQPYPTRREIEKLAASLWLWKSDIASHFSNKRKKCVRDCEKYKPGVLLGFNMKELNKVKHEMDFDAEWLFENHDEKNSRVNVSKTVDKKINIEKDNESSSDSYENIEEEYNESSSPFGPHISDIGEKASPDSIAENPDDGISKEIIEENTLPSPEKSDQKQEESSKYEEMISAEEQTKLVGDVSDSEGYQDDQDDAVEWKDGASQSESGPGSQQVSDFEDNTSEVKPEVWTDESSQSEDAGSSKPTAETKGGGSESDEEQSKWKNRSYGKVEEFWAKDQSQWKNASEIEESLTNQQMEWQNSTIDSEDGDQFDSVTDGVADPMHSSLSGVELSSQQA", "length": 1123, "header": "tr|A0A8V0YH19-1|A0A8V0YNF3_CHICK Computationally mapped isoform of Activity dependent neuroprotector homeobox OS=Gallus gallus OX=9031 GN=ADNP PE=1 SV=1 CANONICAL=A0A8V0YNF3-1" }, "locus": { "chromosome": "20", "start_pos": 13769882, "end_pos": 13756807, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034333.1", "url": "https://www.ensembl.org/id/ENSGALT00010034333.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020165.1", "url": "https://www.ensembl.org/id/ENSGALP00010020165.1" } ] } }, { "isoform_ac": "A0A8V0YNF3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNF3/entry#A0A8V0YNF3-1", "sequence": { "sequence": "MLATFNQILCKWGSEKVQQQLMMPRKAFLSQKEKQARARERDMLKKRRRRQDYLKRSVDPQKNAETIKWHRDDEKRRENEQVKDKDIKKRWRQDERERRKNVDAMNWRREDEKRENERETMFQLPVNNLGSLRKARKTVKKILSDIGLEYCKEHIEDFKQFEPNDFYLKNTTWEDVGLWDPSLTKNQDYRTKPFCCSACPFSSKFFSAYKSHFRNVHSEDFENRILLNCPYCTFNADKKTLETHIKIFHAPNANTPSGGISTFKDKNKHDSLKPKQADSVEQAVYYCKKCTYRDPLYEIVRKHIYREHFQHVAAPYVAKGGEKSLNGAVPLSSSTREEGSIHCKRCLFMPKSYEALVQHVIEDHERIGYQVTAMIGHTNVVVPRSKPLMLIAPKPQDKKPMGLPQRMGPLSPGSVRSLSSQQMMNRLTIPKPTLNSAGVNMMSNVHLQQNNYGVKSVPPSYVGQPGGRLSLSGNAPVSIPQQSQTMKQFSSGNGRPYALGEQRSQASARYSLQSANSTSLSSAQLKQTSLSQSQAASRVLGQSGSKSPVAATGPSSVNTSSTQKWKICTICNELFPENVYSVHFEKEHKAEKVPAVANYIMKIHNFTSKCLYCNRYLPTDTLLNHMLIHGLSCPYCRSTFNDVEKMAAHMRMVHVDEEMGPKTDSTLTFDLTLQQGSLTNIHLLVTTYNLRDAPAESVAYHAQNTPPVPPKPQPKIQEKSDVPVKSSPQAAVPYKKDVGKTLCPLCFSILKGPISDALAHHLRERHQVIQTVHPVEKKLTYKCIHCLGVYTSNMTASTITLHLVHCRGVGKTQNGQDKGTSSSRLSQSAGVAPVKRTYEHMEFSLMKRRKMDDDDSPSAFEEKPEEPVVLALDPKGHEDDSYEARKTFLTKYFNKQPYPTRREIEKLAASLWLWKSDIASHFSNKRKKCVRDCEKYKPGVLLGFNMKELNKVKHEMDFDAEWLFENHDEKNSRVNVSKTVDKKINIEKDNESSSDSYENIEEEYNESSSPFGPHISDIGEKASPDSIAENPDDGISKEIIEENTLPSPEKSDQKQEESSKYEEMISAEEQTKLVGDVSDSEGYQDDQDDAVEWKDGASQSESGPGSQQVSDFEDNTSEVKPEVWTDESSQSEDAGSSKPTAETKGGGSESDEEQSKWKNRSYGKVEEFWAKDQSQWKNASEIEESLTNQQMEWQNSTIDSEDGDQFDSVTDGVADPMHSSLSGVELSSQQA", "length": 1231, "header": "tr|A0A8V0YNF3-1|A0A8V0YNF3_CHICK Isoform 1 of Activity dependent neuroprotector homeobox OS=Gallus gallus OX=9031 GN=ADNP PE=1 SV=1 CANONICAL=A0A8V0YNF3-1" }, "locus": { "chromosome": "20", "start_pos": 13769882, "end_pos": 13755560, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034336.1", "url": "https://www.ensembl.org/id/ENSGALT00010034336.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020167.1", "url": "https://www.ensembl.org/id/ENSGALP00010020167.1" } ] } }, { "isoform_ac": "A0A8V0YNF7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNF3/entry#A0A8V0YNF7-1", "sequence": { "sequence": "MSGLWPHTVQQQLMMPRKAFLSQKEKQARARERDMLKKRRRRQDYLKRSVDPQKNAETIKWHRDDEKRRENEQVKDKDIKKRWRQDERERRKNVDAMNWRREDEKRENERETMFQLPVNNLGSLRKARKTVKKILSDIGLEYCKEHIEDFKQFEPNDFYLKNTTWEDVGLWDPSLTKNQDYRTKPFCCSACPFSSKFFSAYKSHFRNVHSEDFENRILLNCPYCTFNADKKTLETHIKIFHAPNANTPSGGISTFKDKNKHDSLKPKQADSVEQAVYYCKKCTYRDPLYEIVRKHIYREHFQHVAAPYVAKGGEKSLNGAVPLSSSTREEGSIHCKRCLFMPKSYEALVQHVIEDHERIGYQVTAMIGHTNVVVPRSKPLMLIAPKPQDKKPMGLPQRMGPLSPGSVRSLSSQQMMNRLTIPKPTLNSAGVNMMSNVHLQQNNYGVKSVPPSYVGQPGGRLSLSGNAPVSIPQQSQTMKQFSSGNGRPYALGEQRSQASARYSLQSANSTSLSSAQLKQTSLSQSQAASRVLGQSGSKSPVAATGPSSVNTSSTQKWKICTICNELFPENVYSVHFEKEHKAEKVPAVANYIMKIHNFTSKCLYCNRYLPTDTLLNHMLIHGLSCPYCRSTFNDVEKMAAHMRMVHVDEEMGPKTDSTLTFDLTLQQGSLTNIHLLVTTYNLRDAPAESVAYHAQNTPPVPPKPQPKIQEKSDVPVKSSPQAAVPYKKDVGKTLCPLCFSILKGPISDALAHHLRERHQVIQTVHPVEKKLTYKCIHCLGVYTSNMTASTITLHLVHCRGVGKTQNGQDKGTSSSRLSQSAGVAPVKRTYEHMEFSLMKRRKMDDDDSPSAFEEKPEEPVVLALDPKGHEDDSYEARKTFLTKYFNKQPYPTRREIEKLAASLWLWKSDIASHFSNKRKKCVRDCEKYKPGVLLGFNMKELNKVKHEMDFDAEWLFENHDEKNSRVNVSKTVDKKINIEKDNESSSDSYENIEEEYNESSSPFGPHISDIGEKASPDSIAENPDDGISKEIIEENTLPSPEKSDQKQEESSKYEEMISAEEQTKLVGDVSDSEGYQDDQDDAVEWKDGASQSESGPGSQQVSDFEDNTSEVKPEVWTDESSQSEDAGSSKPTAETKGGGSESDEEQSKWKNRSYGKVEEFWAKDQSQWKNASEIEESLTNQQMEWQNSTIDSEDGDQFDSVTDGVADPMHSSLSGVELSSQQA", "length": 1223, "header": "tr|A0A8V0YNF7-1|A0A8V0YNF7_CHICK Computationally mapped isoform of Activity dependent neuroprotector homeobox OS=Gallus gallus OX=9031 GN=ADNP PE=1 SV=1 CANONICAL=A0A8V0YNF3-1" }, "locus": { "chromosome": "20", "start_pos": 13769882, "end_pos": 13753390, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034345.1", "url": "https://www.ensembl.org/id/ENSGALT00010034345.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020172.1", "url": "https://www.ensembl.org/id/ENSGALP00010020172.1" } ] } }, { "isoform_ac": "A0A8V0YNG2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNF3/entry#A0A8V0YNG2-1", "sequence": { "sequence": "MEYCMLGTSAFHKVQQQLMMPRKAFLSQKEKQARARERDMLKKRRRRQDYLKRSVDPQKNAETIKWHRDDEKRRENEQVKDKDIKKRWRQDERERRKNVDAMNWRREDEKRENERETMFQLPVNNLGSLRKARKTVKKILSDIGLEYCKEHIEDFKQFEPNDFYLKNTTWEDVGLWDPSLTKNQDYRTKPFCCSACPFSSKFFSAYKSHFRNVHSEDFENRILLNCPYCTFNADKKTLETHIKIFHAPNANTPSGGISTFKDKNKHDSLKPKQADSVEQAVYYCKKCTYRDPLYEIVRKHIYREHFQHVAAPYVAKGGEKSLNGAVPLSSSTREEGSIHCKRCLFMPKSYEALVQHVIEDHERIGYQVTAMIGHTNVVVPRSKPLMLIAPKPQDKKPMGLPQRMGPLSPGSVRSLSSQQMMNRLTIPKPTLNSAGVNMMSNVHLQQNNYGVKSVPPSYVGQPGGRLSLSGNAPVSIPQQSQTMKQFSSGNGRPYALGEQRSQASARYSLQSANSTSLSSAQLKQTSLSQSQAASRVLGQSGSKSPVAATGPSSVNTSSTQKWKICTICNELFPENVYSVHFEKEHKAEKVPAVANYIMKIHNFTSKCLYCNRYLPTDTLLNHMLIHGLSCPYCRSTFNDVEKMAAHMRMVHVDEEMGPKTDSTLTFDLTLQQGSLTNIHLLVTTYNLRDAPAESVAYHAQNTPPVPPKPQPKIQEKSDVPVKSSPQAAVPYKKDVGKTLCPLCFSILKGPISDALAHHLRERHQVIQTVHPVEKKLTYKCIHCLGVYTSNMTASTITLHLVHCRGVGKTQNGQDKGTSSSRLSQSAGVAPVKRTYEHMEFSLMKRRKMDDDDSPSAFEEKPEEPVVLALDPKGHEDDSYEARKTFLTKYFNKQPYPTRREIEKLAASLWLWKSDIASHFSNKRKKCVRDCEKYKPGVLLGFNMKELNKVKHEMDFDAEWLFENHDEKNSRVNVSKTVDKKINIEKDNESSSDSYENIEEEYNESSSPFGPHISDIGEKASPDSIAENPDDGISKEIIEENTLPSPEKSDQKQEESSKYEEMISAEEQTKLVGDVSDSEGYQDDQDDAVEWKDGASQSESGPGSQQVSDFEDNTSEVKPEVWTDESSQSEDAGSSKPTAETKGGGSESDEEQSKWKNRSYGKVEEFWAKDQSQWKNASEIEESLTNQQMEWQNSTIDSEDGDQFDSVTDGVADPMHSSLSGVELSSQQA", "length": 1228, "header": "tr|A0A8V0YNG2-1|A0A8V0YNG2_CHICK Computationally mapped isoform of Activity dependent neuroprotector homeobox OS=Gallus gallus OX=9031 GN=ADNP PE=1 SV=1 CANONICAL=A0A8V0YNF3-1" }, "locus": { "chromosome": "20", "start_pos": 13769882, "end_pos": 13754874, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034351.1", "url": "https://www.ensembl.org/id/ENSGALT00010034351.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020177.1", "url": "https://www.ensembl.org/id/ENSGALP00010020177.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-9940465", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9940465", "resource": "Reactome", "description": "ChAHP complex assembly" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8M3B615-1", "protein_name": "Activity-dependent neuroprotector homeobox b isoform X1", "gene_name": "adnpb", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MRAHTHLCTSGRRMFQLPVNNLSSLRKARKNVKKVLGDIGLDFCKEHVDDYKDFVPNEFYLKNTTWDDVCMWDPSMTKSQDYRSKPFCCSGCTFSSKFFSAYKSHFRNVHSEDFENRILLNCPYCTYNGNKKTLETHIRLFHMPNVVRQNTGGLHGAGVGLKDGARLEKTRDNIEQAVYYCKKCTYRDPLYNVVRKHIYREHFQHVAAPYLVRPGEKTTTPNGTTAGSGTGSTTDGGVANSMSTAIHCKRCLFVPRTYEALVQHVIEDHERIGYQVTAMIGHTNVVVPRAKPVIMVSPKSQSEKTVGGVMPKSAVVTGVRPLSTQQLSRIVIPKGSLNSSGLLSGVHLKQGVFGLKPGATQSLSIGGQQVQLSIPQQSQTSKPQLSASLRSAVSASASTSILKIPQLNSRVQAAATTVSAVTSKKGNSVIGTSYTQKWKICTICNELFPENVYSSHFEKEHKAEKVPAVANYIMKIHNFTSKCLYCNRYLPSDTLLNHMLIHGLSCPHCRATFNDVEKMVTHMRGVHPNESVGPRTDSPLTFDLTLQQGNPKNVQLIVTTYNMRDAPEESVAFHAQNNALPPSLQGNKQVTPTIPKIPSDASGAMPVKATPQAAVPYKKDIGKTLCPLCFSILKGPISDSLAHHLRDRHQVIQTVHPVEKKLTYKCIHCLGVYTSNMTASTITLHLVHCRGVSKTQNGRPAPSARVVQAQGAGLKRAGLANFDQTEPKRKKPDDQTGQSPSPSTEKHEEPVVFALDPKGYENESYETRKAFLTQYFNKQPYPTRREVEKLASSLWLWKSDIASHFSNRRRRCLLNCETLNTRVLMGFKMEDVLNLDHPLNFDSKCYFQNHKHDHKRRTTRFRIGRSANAILLRQKATTNGDLQQKHEMLPRVSSKALLYSNGQNAIIGSNCFDSVKSTLKSGALVNSEPISVDSDSDNEGNVQDASLTALSLSHEEPATNDKVEGSDSDVRENAHSENGYGSTDLLNETSQQDDECQSGITNKLEQSETQLTEQQV", "length": 1016 }, "evidence": [ { "id": "A0A8V0YNF3", "url": "https://omabrowser.org/oma/group/A0A8V0YNF3/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "E1BCZ9-1", "protein_name": "Activity-dependent neuroprotector homeobox protein", "gene_name": "ADNP", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MFQLPVNNLGSLRKARKTVKKILSDIGLEYCKEHIEDFKQFEPNDFYLKNTTWEDVGLWDPSLTKNQDYRTKPFCCSACPFSSKFFSAYKSHFRNVHSEDFENRILLNCPYCTFNADKKTLETHIKIFHAPNASAPSSSLSTFKDKSKSDGLKPKQADSVEQAVYYCKKCTYRDPLYEIVRKHIYREHFQHVAAPYIAKAGEKSLNGAVPLGTNAREESSIHCKRCLFMPKSYEALVQHVIEDHERIGYQVTAMIGHTNVVVPRSKPLMLIAPKPQEKKGMGLQSRIGSLASGNVRSLPSQQMVNRLSIPKPNVNSTGVNMMSNVHLQQNNYGVKSVGQGYGVGQSMRLGLGGNAPVSIPQQSQSVKQLLPSGNGRSYGLGSEQRTQAPARYSLQSPNAPSLSSGQLKSPSLSQSQASRVLGQSSSKPTAAATGPPPPNTSSTQKWKICTICNELFPENVYSVHFEKEHKAEKVPAVANYIMKIHNFTSKCLYCNRYLPTDTLLNHMLIHGLSCPYCRSTFNDVEKMAAHMRMVHVDEEMGPKTDSTLSFDLTLQQGSHTNIHLLVTTYNLRDAPAESVAYHAQNNPPIPPKPQPKVQEKADIPVKSSPQAAVPYKKDVGKTLCPLCFSILKGPISDALAHHLRERHQVIQTVHPVEKKLTYKCIHCLGVYTSNMTASTITLHLVHCRGVGKTQNGQDKTNAPSRLNQSPGLAPVKRTYEQMEFPLLKKRKLDEDSDSPGFFEEKPEEPVVLALDPKGHEDDSYEARKSFLTKYFNKQPYPTRREIEKLAASLWLWKSDIASHFSNKRKKCVRDCEKYKPGVLLGFNMKELNKVKHEMDFDAEWLFENHDEKDSRVNASKTADKKLNLGKEDDSSSDSFENLEEESNGSDSPFDPVFEVEPKIPNDNPEEHIPKVISEDALESEKLDQKAEDGSKYETIHLTEEPTKLMHDASDSEVDQDDVVEWKDGASPSESGPGSQQVSDFEDNTCEMKAGTWSDESSQSEDARSSKPAAKKKATVQGDREQLKWKNSSYGKVEGFWSKDQSQWKNATENDERLSTPQIEWQNSTIDSEDGEQFDSMADGVADPMHGSLTGVKLSSQQA", "length": 1102 }, "evidence": [ { "id": "A0A8V0YNF3", "url": "https://omabrowser.org/oma/group/A0A8V0YNF3/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "G3HEU6-1", "protein_name": "Activity-dependent neuroprotector homeobox protein", "gene_name": "Adnp", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MFQLPVNNLGSLRKARKTVKKILSDIGLEYCKEHIEDFKQFEPNDFYLKNTTWEDVGLWDPSLTKNQDYRTKPFCCSACPFSSKFFSAYKSHFRNVHSEDFENRILLNCPYCTFNADKKTLETHIKIFHAPNSSAPSSSLSTFKDKNKNDGLKPKQADSVEQAVYYCKKCTYRDPLYEIVRKHIYREHFQHVAAPYIAKAGEKSLNGAVPLGTNAREECNIHCKRCLFMPKSYEALVQHVIEDHERIGYQVTAMIGHTNVVVPRAKPLMLIAPKPQEKKGMGLPPRISSLTSGNVRSLPSQQMVNRLSIPKPNLNSAGVNMMSNVHLQQNNYGVKSVGQSYGVGQSVRLGLGGNAPVSIPQQSQSVKQLLPSGNGRSYGLGAEQRPPAAARYSLQTANTSLPPGQVKSPSVSQSQASRVLGQSGSKPPPAATGPPPSNHCATQKWKICTICNELFPENVYSVHFEKEHKAEKVPAVANYIMKIHNFTSKCLYCNRYLPTDTLLNHMLIHGLSCPYCRSTFNDVEKMAAHMRMVHIDEEMGPKTDSTLSFDLTLQQGSHTNIHLLVTTYNLRDAPAESVAYHAQNNAPVPPKPQPKVQEKADVPVKSSPQAAVPYKKDVGKTLCPLCFSILKGPISDALAHHLRERHQVIQTVHPVEKKLTYKCIHCLGVYTSNMTASTITLHLVHCRGVGKTQNGQDKTNAPSRLNQSPGLAPVKRTYEQVEFPLLKKRKLEDDSDSPSCIEEKPEEPVVLALDPKGHEDDSYEARKSFLTKYFNKQPYPTRREIEKLAASLWLWKSDIASHFSNKRKKCVRDCEKYKPGVLLGFNMKELNKVKHEMDFDAEWLFENHDEKDSRVNASKTVDKKLNLGKEDDSFSDSFEHLEEESNGSGSPFDPVFEVEPKIPSDNPEEHVPKVIPEDALDSEKLDQKEEEDGSKYETVHLTEEPTKLMHDASDSEVDQDDVVEWKDGASPSVSGPGSQQISDFEDNTCEMKTGTWSDESSQSEDARSSKPASKKKATVQEDTEQLKWKNSSYGKVEGFWSKDQSQWENASENAERLPNPQIEWQNSTIDSEDGEQFDSMTDGVADPMHGSLTGVKLSSQQA", "length": 1102 }, "evidence": [ { "id": "A0A8V0YNF3", "url": "https://omabrowser.org/oma/group/A0A8V0YNF3/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q9H2P0-1", "protein_name": "Activity-dependent neuroprotector homeobox protein", "gene_name": "ADNP", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MFQLPVNNLGSLRKARKTVKKILSDIGLEYCKEHIEDFKQFEPNDFYLKNTTWEDVGLWDPSLTKNQDYRTKPFCCSACPFSSKFFSAYKSHFRNVHSEDFENRILLNCPYCTFNADKKTLETHIKIFHAPNASAPSSSLSTFKDKNKNDGLKPKQADSVEQAVYYCKKCTYRDPLYEIVRKHIYREHFQHVAAPYIAKAGEKSLNGAVPLGSNAREESSIHCKRCLFMPKSYEALVQHVIEDHERIGYQVTAMIGHTNVVVPRSKPLMLIAPKPQDKKSMGLPPRIGSLASGNVRSLPSQQMVNRLSIPKPNLNSTGVNMMSSVHLQQNNYGVKSVGQGYSVGQSMRLGLGGNAPVSIPQQSQSVKQLLPSGNGRSYGLGSEQRSQAPARYSLQSANASSLSSGQLKSPSLSQSQASRVLGQSSSKPAAAATGPPPGNTSSTQKWKICTICNELFPENVYSVHFEKEHKAEKVPAVANYIMKIHNFTSKCLYCNRYLPTDTLLNHMLIHGLSCPYCRSTFNDVEKMAAHMRMVHIDEEMGPKTDSTLSFDLTLQQGSHTNIHLLVTTYNLRDAPAESVAYHAQNNPPVPPKPQPKVQEKADIPVKSSPQAAVPYKKDVGKTLCPLCFSILKGPISDALAHHLRERHQVIQTVHPVEKKLTYKCIHCLGVYTSNMTASTITLHLVHCRGVGKTQNGQDKTNAPSRLNQSPSLAPVKRTYEQMEFPLLKKRKLDDDSDSPSFFEEKPEEPVVLALDPKGHEDDSYEARKSFLTKYFNKQPYPTRREIEKLAASLWLWKSDIASHFSNKRKKCVRDCEKYKPGVLLGFNMKELNKVKHEMDFDAEWLFENHDEKDSRVNASKTADKKLNLGKEDDSSSDSFENLEEESNESGSPFDPVFEVEPKISNDNPEEHVLKVIPEDASESEEKLDQKEDGSKYETIHLTEEPTKLMHNASDSEVDQDDVVEWKDGASPSESGPGSQQVSDFEDNTCEMKPGTWSDESSQSEDARSSKPAAKKKATMQGDREQLKWKNSSYGKVEGFWSKDQSQWKNASENDERLSNPQIEWQNSTIDSEDGEQFDNMTDGVAEPMHGSLAGVKLSSQQA", "length": 1102 }, "evidence": [ { "id": "A0A8V0YNF3", "url": "https://omabrowser.org/oma/group/A0A8V0YNF3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9JKL8-1", "protein_name": "Activity-dependent neuroprotector homeobox protein", "gene_name": "Adnp", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFQLPVNNLGSLRKARKTVKKILSDIGLEYCKEHIEDFKQFEPNDFYLKNTTWEDVGLWDPSLTKNQDYRTKPFCCSACPFSSKFFSAYKSHFRNVHSEDFENRILLNCPYCTFNADKKTLETHIKIFHAPNSSAPSSSLSTFKDKNKNDGLKPKQADNVEQAVYYCKKCTYRDPLYEIVRKHIYREHFQHVAAPYIAKAGEKSLNGAVSLGTNAREECNIHCKRCLFMPKSYEALVQHVIEDHERIGYQVTAMIGHTNVVVPRAKPLMLIAPKPQEKKSMGLPPRISSLASGNVRSLPSQQMVNRLSIPKPNLNSTGVNMMSNVHLQQNNYGVKSVGQSYGVGQSVRLGLGGNAPVSIPQQSQSVKQLLPSGNGRSYGLGAEQRPPAAARYSLQTANTSSLPPGQVKSPSVSQSQASRVLGQSSSKPPPAATGPPPSNHCATQKWKICTICNELFPENVYSVHFEKEHKAEKVPAVANYIMKIHNFTSKCLYCNRYLPTDTLLNHMLIHGLSCPYCRSTFNDVEKMAAHMRMVHIDEEMGPKTDSTLSFDLTLQQGSHTNIHLLVTTYNLRDAPAESVAYHAQNNAPVPPKPQPKVQEKADVPVKSSPQAAVPYKKDVGKTLCPLCFSILKGPISDALAHHLRERHQVIQTVHPVEKKLTYKCIHCLGVYTSNMTASTITLHLVHCRGVGKTQNGQDKTNAPSRLNQSPGLAPVKRTYEQMEFPLLKKRKLEDENDSPGCFEEKPEEPVVLALDPKGHEDDSYEARKSFLTKYFNKQPYPTRREIEKLAASLWLWKSDIASHFSNKRKKCVRDCEKYKPGVLLGFNMKELNKVKHEMDFDAEWLFENHDEKASRVNASKTVDKKLNLGKEDDSFSDSFEHLEEESNGSGGPFDPVFEVEPKIPSDNAEEPVPKVIPEGALESEKLDQKEEEDGSKYETIHLTEERAKLMHDASDSEVDQDDVVEWKDGASPSESGPGSRQVSDFEDNTCEMKPGTWSDESSQSEDARSSKPAAKKKATVQDDTEQLKWKNSSYGKVEGFWSKDQSQWENASENAERLPNPQIEWQNSTIDSEDGEQFDSMTDGVADPMHGSLTGVKLSSQQA", "length": 1103 }, "evidence": [ { "id": "A0A8V0YNF3", "url": "https://omabrowser.org/oma/group/A0A8V0YNF3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9Z103-1", "protein_name": "Activity-dependent neuroprotector homeobox protein", "gene_name": "Adnp", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFQLPVNNLGSLRKARKTVKKILSDIGLEYCKEHIEDFKQFEPNDFYLKNTTWEDVGLWDPSLTKNQDYRTKPFCCSACPFSSKFFSAYKSHFRNVHSEDFENRILLNCPYCTFNADKKTLETHIKIFHAPNSSAPSSSLSTFKDKNKNDGLKPKQADNVEQAVYYCKKCTYRDPLYEIVRKHIYREHFQHVAAPYIAKAGEKSLNGAVSLGTNAREECNIHCKRCLFMPKSYEALVQHVIEDHERIGYQVTAMIGHTNVVVPRAKPLMLIAPKPQDKKGMGLPPRISSLASGNVRSLPSQQMVNRLSIPKPNLNSTGVNMMSNVHLQQNNYGVKSVGQSYGVGQSVRLGLGGNAPVSIPQQSQSVKQLLPSGNGRSFGLGAEQRPPAAARYSLQTANTSLPPGQVKSPSVSQSQASRVLGQSSSKPPPAATGPPPSNHCATQKWKICTICNELFPENVYSVHFEKEHKAEKVPAVANYIMKIHNFTSKCLYCNRYLPTDTLLNHMLIHGLSCPYCRSTFNDVEKMAAHMRMVHIDEEMGPKTDSTLSFDLTLQQGSHTNIHLLVTTYNLRDAPAESVAYHAQNNAPVPPKPQPKVQEKADVPVKSSPQAAVPYKKDVGKTLCPLCFSILKGPISDALAHHLRERHQVIQTVHPVEKKLTYKCIHCLGVYTSNMTASTITLHLVHCRGVGKTQNGQDKTNAPSRLNQSPGLAPVKRTYEQMEFPLLKKRKLEEDADSPSCFEEKPEEPVVLALDPKGHEDDSYEARKSFLTKYFNKQPYPTRREIEKLAASLWLWKSDIASHFSNKRKKCVRDCEKYKPGVLLGFNMKELNKVKHEMDFDAEWLFENHDEKDSRVNASKTVDKKHNLGKEDDSFSDSFEHLEEESNGSGSPFDPVFEVEPKIPSDNLEEPVPKVIPEGALESEKLDQKEEEEEEEEEDGSKYETIHLTEEPAKLMHDASDSEVDQDDVVEWKDGASPSESGPGSQQISDFEDNTCEMKPGTWSDESSQSEDARSSKPAAKKKATVQDDTEQLKWKNSSYGKVEGFWSKDQSQWENASENAERLPNPQIEWQNSTIDSEDGEQFDSMTDGVADPMHGSLTGVKLSSQQA", "length": 1108 }, "evidence": [ { "id": "A0A8V0YNF3", "url": "https://omabrowser.org/oma/group/A0A8V0YNF3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 6, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNF3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNF3" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNF3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNF3" } ], "pmid": "" }, { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNF3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNF3" } ], "pmid": "" }, { "name": "RNA polymerase II transcription regulatory region sequence-specific DNA binding", "id": "GO:0000977", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000977", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNF3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNF3" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNF3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNF3" } ], "pmid": "" }, { "name": "beta-catenin binding", "id": "GO:0008013", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008013", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNF3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNF3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNF3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNF3" } ], "pmid": "" }, { "name": "chromosome", "id": "GO:0005694", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005694", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNF3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNF3" } ], "pmid": "" }, { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNF3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNF3" } ], "pmid": "" }, { "name": "RNA polymerase II transcription regulator complex", "id": "GO:0090575", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090575", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNF3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNF3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNF3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNF3" } ], "pmid": "" }, { "name": "neuron differentiation", "id": "GO:0030182", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030182", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNF3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNF3" } ], "pmid": "" }, { "name": "positive regulation of canonical Wnt signaling pathway", "id": "GO:0090263", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090263", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNF3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNF3" } ], "pmid": "" }, { "name": "regulation of gene expression", "id": "GO:0010468", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010468", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNF3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNF3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1005, "end_pos": 1007, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1115, "end_pos": 1117, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1159, "end_pos": 1161, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1178, "end_pos": 1180, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1195, "end_pos": 1197, "annotation": "n_glycosylation_sequon" }, { "start_pos": 170, "end_pos": 172, "annotation": "n_glycosylation_sequon" }, { "start_pos": 516, "end_pos": 518, "annotation": "n_glycosylation_sequon" }, { "start_pos": 558, "end_pos": 560, "annotation": "n_glycosylation_sequon" }, { "start_pos": 605, "end_pos": 607, "annotation": "n_glycosylation_sequon" }, { "start_pos": 793, "end_pos": 795, "annotation": "n_glycosylation_sequon" }, { "start_pos": 975, "end_pos": 977, "annotation": "n_glycosylation_sequon" }, { "start_pos": 990, "end_pos": 992, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YNF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNF3" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 631, "end_pos": 659, "start_aa": "Leu", "end_aa": "Met", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0YNF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNF3" }, { "id": "PS50071", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50071" }, { "id": "PRU00108", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00108" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Homeobox", "eco_id": "ECO_0000259", "start_pos": 889, "end_pos": 932, "start_aa": "Leu", "end_aa": "Asp", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1005, "end_pos": 1007 }, { "start_pos": 1115, "end_pos": 1117 }, { "start_pos": 1159, "end_pos": 1161 }, { "start_pos": 1178, "end_pos": 1180 }, { "start_pos": 1195, "end_pos": 1197 }, { "start_pos": 170, "end_pos": 172 }, { "start_pos": 516, "end_pos": 518 }, { "start_pos": 558, "end_pos": 560 }, { "start_pos": 605, "end_pos": 607 }, { "start_pos": 793, "end_pos": 795 }, { "start_pos": 975, "end_pos": 977 }, { "start_pos": 990, "end_pos": 992 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YQ79-1", "uniprot_ac": "A0A8V0YQ79", "uniprot_id": "A0A8V0YQ79_CHICK", "mass": { "chemical_mass": 38491.0, "monoisotopic_mass": 38491.0 }, "refseq": {}, "gene_names": [ { "name": "PCBP3", "type": "recommended", "evidence": [ { "id": "A0A8V0YQ79", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ79" } ] } ], "protein_names": [ { "name": "Poly(rC) binding protein 3", "type": "synonym", "evidence": [ { "id": "A0A8V0YQ79", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ79/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQ79", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ79" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PCBP3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ79", "locus": {} } ], "crossref": [ { "id": "A0A8V0YQ79", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YQ79", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd22516", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22516", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd22519", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22519", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd22522", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22522", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100858906", "url": "https://www.ncbi.nlm.nih.gov/gene/100858906", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004088", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004088", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036612", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036612", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:100858906", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100858906", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YH23", "url": "https://www.orthodb.org/?gene=A0A8V0YH23", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YNA6", "url": "https://www.orthodb.org/?gene=A0A8V0YNA6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YNB8", "url": "https://www.orthodb.org/?gene=A0A8V0YNB8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YNE7", "url": "https://www.orthodb.org/?gene=A0A8V0YNE7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YQ79", "url": "https://www.orthodb.org/?gene=A0A8V0YQ79", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YV79", "url": "https://www.orthodb.org/?gene=A0A8V0YV79", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YV85", "url": "https://www.orthodb.org/?gene=A0A8V0YV85", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10288", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10288", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00013", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00013", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YH23", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH23", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YH23-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH23-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YNA6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNA6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YNA6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNA6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YNB8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNB8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YNB8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNB8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YNE7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNE7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YNE7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNE7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQ79", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ79", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQ79-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ79-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YV79", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YV79", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YV79-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YV79-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YV85", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YV85", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YV85-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YV85-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MESKVSEGGLNVTLTIRLLMHGKEVGSIIGKKGETVKKMREESGARINISEGNCPERIVTITGPTDAIFKAFAMIAYKFEEDITNSMSNSTATSKPPVTLRLVVPASQCGSLIGKGGSKIKEIRESTGAQVQVAGDMLPNSTERAVTISGTPDAIIQCVKQICVVMLESPPKGATIPYRPKPASTPVIFAGGQVRADPLAASTANLSLLLQHQPLPAYTIQGQYAIPHPDLTKLHQLAMQQTPFTPLGQTTPAFPGEKLPLHSSEEAQNLMGQSSGLDASPPASTHELTIPNDLIGCIIGRQGTKINEIRQMSGAQIKIANATEGSSERQITITGTPANISLAQYLINASFPDPEPHGRTFPA", "length": 363, "header": "tr|A0A8V0YQ79-1|A0A8V0YQ79_CHICK Isoform 1 of Poly(rC) binding protein 3 OS=Gallus gallus OX=9031 GN=PCBP3 PE=4 SV=1 CANONICAL=A0A8V0YQ79-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YH23-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ79/entry#A0A8V0YH23-1", "sequence": { "sequence": "MESKVSEGGLNVTLTIRLLMHGKEVGSIIGKKGETVKKMREESGARINISEGNCPERIVTITGPTDAIFKAFAMIAYKFEEDITNSMSNSTATSKPPVTLRLVVPASQCGSLIGKGGSKIKEIRESTGAQVQVAGDMLPNSTERAVTISGTPDAIIQCVKQICVVMLESPPKGATIPYRPKPASTPVIFAGGQVRADPLAASTANLSLLLQHQPLPAYTIQGQYAIPHPDVWMPVPRPVLMNSPFPMI", "length": 248, "header": "tr|A0A8V0YH23-1|A0A8V0YQ79_CHICK Computationally mapped isoform of Poly(rC) binding protein 3 OS=Gallus gallus OX=9031 GN=PCBP3 PE=4 SV=1 CANONICAL=A0A8V0YQ79-1" }, "locus": { "chromosome": "7", "start_pos": 6761595, "end_pos": 6746034, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034342.1", "url": "https://www.ensembl.org/id/ENSGALT00010034342.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020170.1", "url": "https://www.ensembl.org/id/ENSGALP00010020170.1" } ] } }, { "isoform_ac": "A0A8V0YNA6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ79/entry#A0A8V0YNA6-1", "sequence": { "sequence": "MESKVSEGGLNVTLTIRLLMHGKEVGSIIGKKGETVKKMREESGARINISEGNCPERIVTITGPTDAIFKAFAMIAYKFEEDITNSMSNSTATSKPPVTLRLVVPASQCGSLIGKGGSKIKEIRESTGAQVQVAGDMLPNSTERAVTISGTPDAIIQCVKQICVVMLESPPKGATIPYRPKPASTPVIFAGGQAYTIQGQYAIPHPDLSRSRAPREDLPCVTSCSSSHPQCPRCPGATCFCHQPHFSIPWPPAAL", "length": 255, "header": "tr|A0A8V0YNA6-1|A0A8V0YNA6_CHICK Computationally mapped isoform of Poly(rC) binding protein 3 OS=Gallus gallus OX=9031 GN=PCBP3 PE=4 SV=1 CANONICAL=A0A8V0YQ79-1" }, "locus": { "chromosome": "7", "start_pos": 6769754, "end_pos": 6746034, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034330.1", "url": "https://www.ensembl.org/id/ENSGALT00010034330.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020164.1", "url": "https://www.ensembl.org/id/ENSGALP00010020164.1" } ] } }, { "isoform_ac": "A0A8V0YNB8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ79/entry#A0A8V0YNB8-1", "sequence": { "sequence": "MESKVSEGGLNVTLTIRLLMHGKEVGSIIGKKGETVKKMREESGARINISEGNCPERIVTITGPTDAIFKAFAMIAYKFEEDITNSMSNSTATSKPPVTLRLVVPASQCGSLIGKGGSKIKEIRESTGAQVQVAGDMLPNSTERAVTISGTPDAIIQCVKQICVVMLESPPKGATIPYRPKPASTPVIFAGGQAYTIQGQYAIPHPDQLTKLHQLAMQQTPFTPLGQTTPAFPGEKLPLHSSEEAQNLMGQSSGLDASPPASTHELTIPNDLIGCIIGRQGTKINEIRQMSGAQIKIANATEGSSERQITITGTPANISLAQYLINARLTSEVTGMGAL", "length": 339, "header": "tr|A0A8V0YNB8-1|A0A8V0YNB8_CHICK Computationally mapped isoform of Poly(rC) binding protein 3 OS=Gallus gallus OX=9031 GN=PCBP3 PE=4 SV=1 CANONICAL=A0A8V0YQ79-1" }, "locus": { "chromosome": "7", "start_pos": 6763143, "end_pos": 6746034, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034347.1", "url": "https://www.ensembl.org/id/ENSGALT00010034347.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020174.1", "url": "https://www.ensembl.org/id/ENSGALP00010020174.1" } ] } }, { "isoform_ac": "A0A8V0YNE7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ79/entry#A0A8V0YNE7-1", "sequence": { "sequence": "MESKVSEGGLNVTLTIRLLMHGKEVGSIIGKKGETVKKMREESGARINISEGNCPERIVTITGPTDAIFKAFAMIAYKFEEDITNSMSNSTATSKPPVTLRLVVPASQCGSLIGKGGSKIKEIRESTGAQVQVAGDMLPNSTERAVTISGTPDAIIQCVKQICVVMLESPPKGATIPYRPKPASTPVIFAGGQAYTIQGQYAIPHPDQLTKLHQLAMQQTPFTPLGQTTPAFPGLDASPPASTHELTIPNDLSRSRAPREDLPCVTSCSSSHPQCPRCPGATCFCHQPHFSIPWPPAAL", "length": 299, "header": "tr|A0A8V0YNE7-1|A0A8V0YNE7_CHICK Computationally mapped isoform of Poly(rC) binding protein 3 OS=Gallus gallus OX=9031 GN=PCBP3 PE=4 SV=1 CANONICAL=A0A8V0YQ79-1" }, "locus": { "chromosome": "7", "start_pos": 6769754, "end_pos": 6746034, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034327.1", "url": "https://www.ensembl.org/id/ENSGALT00010034327.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020162.1", "url": "https://www.ensembl.org/id/ENSGALP00010020162.1" } ] } }, { "isoform_ac": "A0A8V0YQ79-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ79/entry#A0A8V0YQ79-1", "sequence": { "sequence": "MESKVSEGGLNVTLTIRLLMHGKEVGSIIGKKGETVKKMREESGARINISEGNCPERIVTITGPTDAIFKAFAMIAYKFEEDITNSMSNSTATSKPPVTLRLVVPASQCGSLIGKGGSKIKEIRESTGAQVQVAGDMLPNSTERAVTISGTPDAIIQCVKQICVVMLESPPKGATIPYRPKPASTPVIFAGGQVRADPLAASTANLSLLLQHQPLPAYTIQGQYAIPHPDLTKLHQLAMQQTPFTPLGQTTPAFPGEKLPLHSSEEAQNLMGQSSGLDASPPASTHELTIPNDLIGCIIGRQGTKINEIRQMSGAQIKIANATEGSSERQITITGTPANISLAQYLINASFPDPEPHGRTFPA", "length": 363, "header": "tr|A0A8V0YQ79-1|A0A8V0YQ79_CHICK Isoform 1 of Poly(rC) binding protein 3 OS=Gallus gallus OX=9031 GN=PCBP3 PE=4 SV=1 CANONICAL=A0A8V0YQ79-1" }, "locus": { "chromosome": "7", "start_pos": 6769650, "end_pos": 6746034, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034353.1", "url": "https://www.ensembl.org/id/ENSGALT00010034353.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020178.1", "url": "https://www.ensembl.org/id/ENSGALP00010020178.1" } ] } }, { "isoform_ac": "A0A8V0YV79-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ79/entry#A0A8V0YV79-1", "sequence": { "sequence": "MESKVSEGGLNVTLTIRLLMHGKEVGSIIGKKGETVKKMREESGARINISEGNCPERIVTITGPTDAIFKAFAMIAYKFEEDITNSMSNSTATSKPPVTLRLVVPASQCGSLIGKGGSKIKEIRESTGAQVQVAGDMLPNSTERAVTISGTPDAIIQCVKQICVVMLESPPKGATIPYRPKPASTPVIFAGGQAYTIQGQYAIPHPDQLTKLHQLAMQQTPFTPLGQTTPAFPGLDASPPASTHELTIPNDLIGCIIGRQGTKINEIRQMSGAQIKIANATEGSSERQITITGTPANISLAQYLINAR", "length": 308, "header": "tr|A0A8V0YV79-1|A0A8V0YV79_CHICK Computationally mapped isoform of Poly(rC) binding protein 3 OS=Gallus gallus OX=9031 GN=PCBP3 PE=4 SV=1 CANONICAL=A0A8V0YQ79-1" }, "locus": { "chromosome": "7", "start_pos": 6761765, "end_pos": 6746034, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034324.1", "url": "https://www.ensembl.org/id/ENSGALT00010034324.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020161.1", "url": "https://www.ensembl.org/id/ENSGALP00010020161.1" } ] } }, { "isoform_ac": "A0A8V0YV85-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ79/entry#A0A8V0YV85-1", "sequence": { "sequence": "MESKVSEGGLNVTLTIRLLMHGKEVGSIIGKKGETVKKMREESGARINISEGNCPERIVTITGPTDAIFKAFAMIAYKFEEDITNSMSNSTATSKPPVTLRLVVPASQCGSLIGKGGSKIKEIRESTGAQVQVAGDMLPNSTERAVTISGTPDAIIQCVKQICVVMLESPPKGATIPYRPKPASTPVIFAGGQVRADPLAASTANLSLLLQHQPLPAYTIQGQYAIPHPDLTKLHQLAMQQTPFTPLGQTTPAFPGEKLPLHSSEEAQNLMGQSSGLDASPPASTHELTIPNDLIGCIIGRQGTKINEIRQMSGAQIKIANATEGSSERQITITGTPANISLAQYLINARLTSEVTGMGAL", "length": 361, "header": "tr|A0A8V0YV85-1|A0A8V0YV85_CHICK Computationally mapped isoform of Poly(rC) binding protein 3 OS=Gallus gallus OX=9031 GN=PCBP3 PE=4 SV=1 CANONICAL=A0A8V0YQ79-1" }, "locus": { "chromosome": "7", "start_pos": 6763143, "end_pos": 6746034, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034335.1", "url": "https://www.ensembl.org/id/ENSGALT00010034335.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020166.1", "url": "https://www.ensembl.org/id/ENSGALP00010020166.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:100858906", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100858906", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQ79", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ79" } ], "pmid": "" }, { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQ79", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ79" } ], "pmid": "" }, { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQ79", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ79" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQ79", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ79" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQ79", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ79" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQ79", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ79" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 11, "end_pos": 13, "annotation": "n_glycosylation_sequon" }, { "start_pos": 140, "end_pos": 142, "annotation": "n_glycosylation_sequon" }, { "start_pos": 205, "end_pos": 207, "annotation": "n_glycosylation_sequon" }, { "start_pos": 321, "end_pos": 323, "annotation": "n_glycosylation_sequon" }, { "start_pos": 339, "end_pos": 341, "annotation": "n_glycosylation_sequon" }, { "start_pos": 348, "end_pos": 350, "annotation": "n_glycosylation_sequon" }, { "start_pos": 48, "end_pos": 50, "annotation": "n_glycosylation_sequon" }, { "start_pos": 89, "end_pos": 91, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YQ79", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ79" }, { "id": "SM00322", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00322" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "K Homology", "eco_id": "ECO_0000259", "start_pos": 12, "end_pos": 80, "start_aa": "Val", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 11, "end_pos": 13 }, { "start_pos": 140, "end_pos": 142 }, { "start_pos": 205, "end_pos": 207 }, { "start_pos": 321, "end_pos": 323 }, { "start_pos": 339, "end_pos": 341 }, { "start_pos": 348, "end_pos": 350 }, { "start_pos": 48, "end_pos": 50 }, { "start_pos": 89, "end_pos": 91 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YNX0-1", "uniprot_ac": "A0A8V0YNX0", "uniprot_id": "A0A8V0YNX0_CHICK", "mass": { "chemical_mass": 82393.0, "monoisotopic_mass": 82393.0 }, "refseq": {}, "gene_names": [ { "name": "ZBTB33", "type": "recommended", "evidence": [ { "id": "A0A8V0YNX0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNX0" } ] } ], "protein_names": [ { "name": "Transcriptional regulator Kaiso", "type": "recommended", "evidence": [ { "id": "A0A8V0YNX0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNX0/entry#names_and_taxonomy" } ] }, { "name": "Zinc finger and BTB domain-containing protein 33", "type": "synonym", "evidence": [ { "id": "A0A8V0YNX0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNX0/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNX0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNX0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ZBTB33", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNX0", "locus": { "chromosome": "4", "start_pos": 16431174, "end_pos": 16439945, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012821", "url": "https://www.ensembl.org/id/ENSGALG00010012821" } ] } } ], "crossref": [ { "id": "A0A8V0YNX0", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YNX0", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd18219", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18219", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "422367", "url": "https://www.ncbi.nlm.nih.gov/gene/422367", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000210", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000210", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011333", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011333", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050457", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050457", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:422367", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422367", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "VTQVQPN", "url": "https://omabrowser.org/oma/group/VTQVQPN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YAQ4", "url": "https://www.orthodb.org/?gene=A0A8V0YAQ4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YAQ9", "url": "https://www.orthodb.org/?gene=A0A8V0YAQ9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YH25", "url": "https://www.orthodb.org/?gene=A0A8V0YH25", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YH30", "url": "https://www.orthodb.org/?gene=A0A8V0YH30", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YJ44", "url": "https://www.orthodb.org/?gene=A0A8V0YJ44", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YNX0", "url": "https://www.orthodb.org/?gene=A0A8V0YNX0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46105", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46105", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46105:SF27", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46105:SF27", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00651", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00651", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YAQ4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAQ4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YAQ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAQ4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YAQ9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAQ9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YAQ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAQ9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YH25", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH25", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YH25-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH25-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YH30", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH30", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YH30-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH30-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJ44", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ44", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJ44-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ44-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YNX0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNX0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YNX0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNX0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEAAAPPLEACVSRGPSAPEGCRSLSGRGAEGCRARSGGAPGPQGRAARRSAPCRPRSGSGARARRAAAAAGAGARGRGAGRRVPGMEGEKLISATDTQYSSSLLQSLNEQRGHGLFCDVTVIVEDRKFRAHRNILSASSTYFHQLLSVAGQVVELSFVRADIFAEILNYMYSSKIISVRADLIDELIKSGQQLGVKFLADLSVAPSDGRSVPGEVKDGASGTSGSAPTQKDAETQVPAIRQEGREVTGWMPVITESFSLHGIAYETPKITVTDSDDDDDVIFCSEIVPPKECTKDSSAAIQNQPCPNASGASDQKSCGSGGSPLLTSTTSTQKLTSSANQLNPNQTLSSAESLVPVAPQHSTTELILLNRPPVNAPPSVSSSHQTHVPPTIDLVEESQKPSDKGSSTERGTAAVDVEEVVEDSDDVISSSSPSSVSNSSSVQQPSVPKVAPSEGSGVQKKQVVTFPQEQSSKPGEFKIKISDVLSGNNKEFGPGIASKHAGEGQKIITLDTATEIEGLSTGCKVYANIGEDTYDIVIPIKDDPEEGEAKPNEAPRTSDGDSTSRKRMKVKHDDHYELIVDGRVYYICIVCKRSYVCLTSLRRHFNVHSWEKKYPCRYCDKVFPLAEYRTKHEIHHTGERRYQCLTCGKSFINYQIMASHIRSVHSQDPSGDNKLYRLHPCKSLQIRQYAYISDRSSSLPVINENRIVYRVDAAKDGTEGTTSNSPGKQMSWDDIFVPQGNDAIFKQNQSEGSTEFEFVIPESY", "length": 764, "header": "tr|A0A8V0YNX0-1|A0A8V0YNX0_CHICK Isoform 1 of Transcriptional regulator Kaiso OS=Gallus gallus OX=9031 GN=ZBTB33 PE=4 SV=1 CANONICAL=A0A8V0YNX0-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YAQ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNX0/entry#A0A8V0YAQ4-1", "sequence": { "sequence": "MEGEKLISATDTQYSSSLLQSLNEQRGHGLFCDVTVIVEDRKFRAHRNILSASSTYFHQLLSVAGQVVELSFVRADIFAEILNYMYSSKIISVRADLIDELIKSGQQLGVKFLADLSVAPSDGRSVPGEVKDGASGTSGSAPTQKDAETQVPAIRQEGREVTGWMPVITESFSLHGIAYETPKITVTDSDDDDDVIFCSEIVPPKECTKDSSAAIQNQPCPNASGASDQKSCGSGGSPLLTSTTSTQKLTSSANQLNPNQTLSSAESLVPVAPQHSTTELILLNRPPVNAPPSVSSSHQTHVPPTIDLVEESQKPSDKGSSTERGTAAVDVEEVVEDSDDVISSSSPSSVSNSSSVQQPSVPKVAPSEGSGVQKKQVVTFPQEQSSKPGEFKIKISDVLSGNNKEFGPGIASKHAGEGQKIITLDTATEIEGLSTGCKVYANIGEDTYDIVIPIKDDPEEGEAKPNEAPRTSDGDSTSRKRMKVKHDDHYELIVDGRVYYICIVCKRSYVCLTSLRRHFNVHSWEKKYPCRYCDKVFPLAEYRTKHEIHHTGERRYQCLTCGKSFINYQIMASHIRSVHSQDPSGDNKLYRLHPCKSLQIRQYAYISDRSSSLPVINENRIVYRVDAAKDGTEGTTSNSPGKQMSWDDIFVPQGNDAIFKQNQSEGSTEFEFVIPESY", "length": 678, "header": "tr|A0A8V0YAQ4-1|A0A8V0YAQ4_CHICK Computationally mapped isoform of Transcriptional regulator Kaiso OS=Gallus gallus OX=9031 GN=ZBTB33 PE=4 SV=1 CANONICAL=A0A8V0YNX0-1" }, "locus": { "chromosome": "4", "start_pos": 16436053, "end_pos": 16434020, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030752.1", "url": "https://www.ensembl.org/id/ENSGALT00010030752.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017833.1", "url": "https://www.ensembl.org/id/ENSGALP00010017833.1" } ] } }, { "isoform_ac": "A0A8V0YAQ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNX0/entry#A0A8V0YAQ9-1", "sequence": { "sequence": "MEARAKPRPGMEGEKLISATDTQYSSSLLQSLNEQRGHGLFCDVTVIVEDRKFRAHRNILSASSTYFHQLLSVAGQVVELSFVRADIFAEILNYMYSSKIISVRADLIDELIKSGQQLGVKFLADLSVAPSDGRSVPGEVKDGASGTSGSAPTQKDAETQVPAIRQEGREVTGWMPVITESFSLHGIAYETPKITVTDSDDDDDVIFCSEIVPPKECTKDSSAAIQNQPCPNASGASDQKSCGSGGSPLLTSTTSTQKLTSSANQLNPNQTLSSAESLVPVAPQHSTTELILLNRPPVNAPPSVSSSHQTHVPPTIDLVEESQKPSDKGSSTERGTAAVDVEEVVEDSDDVISSSSPSSVSNSSSVQQPSVPKVAPSEGSGVQKKQVVTFPQEQSSKPGEFKIKISDVLSGNNKEFGPGIASKHAGEGQKIITLDTATEIEGLSTGCKVYANIGEDTYDIVIPIKDDPEEGEAKPNEAPRTSDGDSTSRKRMKVKHDDHYELIVDGRVYYICIVCKRSYVCLTSLRRHFNVHSWEKKYPCRYCDKVFPLAEYRTKHEIHHTGERRYQCLTCGKSFINYQIMASHIRSVHSQDPSGDNKLYRLHPCKSLQIRQYAYISDRSSSLPTESEKSLA", "length": 632, "header": "tr|A0A8V0YAQ9-1|A0A8V0YAQ9_CHICK Computationally mapped isoform of Transcriptional regulator Kaiso OS=Gallus gallus OX=9031 GN=ZBTB33 PE=4 SV=1 CANONICAL=A0A8V0YNX0-1" }, "locus": { "chromosome": "4", "start_pos": 16439808, "end_pos": 16431740, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030762.1", "url": "https://www.ensembl.org/id/ENSGALT00010030762.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017838.1", "url": "https://www.ensembl.org/id/ENSGALP00010017838.1" } ] } }, { "isoform_ac": "A0A8V0YH25-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNX0/entry#A0A8V0YH25-1", "sequence": { "sequence": "MVSVGVGGRTHGLGMEGEKLISATDTQYSSSLLQSLNEQRGHGLFCDVTVIVEDRKFRAHRNILSASSTYFHQLLSVAGQVVELSFVRADIFAEILNYMYSSKIISVRADLIDELIKSGQQLGVKFLADLSVAPSDGRSVPGEVKDGASGTSGSAPTQKDAETQVPAIRQEGREVTGWMPVITESFSLHGIAYETPKITVTDSDDDDDVIFCSEIVPPKECTKDSSAAIQNQPCPNASGASDQKSCGSGGSPLLTSTTSTQKLTSSANQLNPNQTLSSAESLVPVAPQHSTTELILLNRPPVNAPPSVSSSHQTHVPPTIDLVEESQKPSDKGSSTERGTAAVDVEEVVEDSDDVISSSSPSSVSNSSSVQQPSVPKVAPSEGSGVQKKQVVTFPQEQSSKPGEFKIKISDVLSGNNKEFGPGIASKHAGEGQKIITLDTATEIEGLSTGCKVYANIGEDTYDIVIPIKDDPEEGEAKPNEAPRTSDGDSTSRKRMKVKHDDHYELIVDGRVYYICIVCKRSYVCLTSLRRHFNVHSWEKKYPCRYCDKVFPLAEYRTKHEIHHTGERRYQCLTCGKSFINYQIMASHIRSVHSQDPSGDNKLYRLHPCKSLQIRQYAYISDRSSSLPVINENRIVYRVDAAKDGTEGTTSNSPGKQMSWDDIFVPQGNDAIFKQNQSEGSTEFEFVIPESY", "length": 692, "header": "tr|A0A8V0YH25-1|A0A8V0YNX0_CHICK Computationally mapped isoform of Transcriptional regulator Kaiso OS=Gallus gallus OX=9031 GN=ZBTB33 PE=4 SV=1 CANONICAL=A0A8V0YNX0-1" }, "locus": { "chromosome": "4", "start_pos": 16437418, "end_pos": 16434020, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030747.1", "url": "https://www.ensembl.org/id/ENSGALT00010030747.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017830.1", "url": "https://www.ensembl.org/id/ENSGALP00010017830.1" } ] } }, { "isoform_ac": "A0A8V0YH30-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNX0/entry#A0A8V0YH30-1", "sequence": { "sequence": "MTREQAEVLDRALSPVPAGCSPRAALAATPGLSGPRRCRNGCQRGPASFPQPAAAAGMEGEKLISATDTQYSSSLLQSLNEQRGHGLFCDVTVIVEDRKFRAHRNILSASSTYFHQLLSVAGQVVELSFVRADIFAEILNYMYSSKIISVRADLIDELIKSGQQLGVKFLADLSVAPSDGRSVPGEVKDGASGTSGSAPTQKDAETQVPAIRQEGREVTGWMPVITESFSLHGIAYETPKITVTDSDDDDDVIFCSEIVPPKECTKDSSAAIQNQPCPNASGASDQKSCGSGGSPLLTSTTSTQKLTSSANQLNPNQTLSSAESLVPVAPQHSTTELILLNRPPVNAPPSVSSSHQTHVPPTIDLVEESQKPSDKGSSTERGTAAVDVEEVVEDSDDVISSSSPSSVSNSSSVQQPSVPKVAPSEGSGVQKKQVVTFPQEQSSKPGEFKIKISDVLSGNNKEFGPGIASKHAGEGQKIITLDTATEIEGLSTGCKVYANIGEDTYDIVIPIKDDPEEGEAKPNEAPRTSDGDSTSRKRMKVKHDDHYELIVDGRVYYICIVCKRSYVCLTSLRRHFNVHSWEKKYPCRYCDKVFPLAEYRTKHEIHHTGERRYQCLTCGKSFINYQIMASHIRSVHSQDPSGDNKLYRLHPCKSLQIRQYAYISDRSSSLPVINENRIVYRVDAAKDGTEGTTSNSPGKQMSWDDIFVPQGNDAIFKQNQSEGSTEFEFVIPESY", "length": 735, "header": "tr|A0A8V0YH30-1|A0A8V0YNX0_CHICK Computationally mapped isoform of Transcriptional regulator Kaiso OS=Gallus gallus OX=9031 GN=ZBTB33 PE=4 SV=1 CANONICAL=A0A8V0YNX0-1" }, "locus": { "chromosome": "4", "start_pos": 16439633, "end_pos": 16434020, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030759.1", "url": "https://www.ensembl.org/id/ENSGALT00010030759.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017835.1", "url": "https://www.ensembl.org/id/ENSGALP00010017835.1" } ] } }, { "isoform_ac": "A0A8V0YJ44-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNX0/entry#A0A8V0YJ44-1", "sequence": { "sequence": "MEARAKPRPGMEGEKLISATDTQYSSSLLQSLNEQRGHGLFCDVTVIVEDRKFRAHRNILSASSTYFHQLLSVAGQVVELSFVRADIFAEILNYMYSSKIISVRADLIDELIKSGQQLGVKFLADLSVAPSDGRSVPGEVKDGASGTSGSAPTQKDAETQVPAIRQEGREVTGWMPVITESFSLHGIAYETPKITVTDSDDDDDVIFCSEIVPPKECTKDSSAAIQNQPCPNASGASDQKSCGSGGSPLLTSTTSTQKLTSSANQLNPNQTLSSAESLVPVAPQHSTTELILLNRPPVNAPPSVSSSHQTHVPPTIDLVEESQKPSDKGSSTERGTAAVDVEEVVEDSDDVISSSSPSSVSNSSSVQQPSVPKVAPSEGSGVQKKQVVTFPQEQSSKPGEFKIKISDVLSGNNKEFGPGIASKHAGEGQKIITLDTATEIEGLSTGCKVYANIGEDTYDIVIPIKDDPEEGEAKPNEAPRTSDGDSTSRKRMKVKHDDHYELIVDGRVYYICIVCKRSYVCLTSLRRHFNVHSWEKKYPCRYCDKVFPLAEYRTKHEIHHTGERRYQCLTCGKSFINYQIMASHIRSVHSQDPSGDNKLYRLHPCKSLQIRQYAYISDRSSSLPVINENRIVYRVDAAKDGTEGTTSNSPGKQMSWDDIFVPQGNDAIFKQNQSEGSTEFEFVIPESY", "length": 688, "header": "tr|A0A8V0YJ44-1|A0A8V0YNX0_CHICK Computationally mapped isoform of Transcriptional regulator Kaiso OS=Gallus gallus OX=9031 GN=ZBTB33 PE=4 SV=1 CANONICAL=A0A8V0YNX0-1" }, "locus": { "chromosome": "4", "start_pos": 16439808, "end_pos": 16434020, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030766.1", "url": "https://www.ensembl.org/id/ENSGALT00010030766.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017841.1", "url": "https://www.ensembl.org/id/ENSGALP00010017841.1" } ] } }, { "isoform_ac": "A0A8V0YNX0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNX0/entry#A0A8V0YNX0-1", "sequence": { "sequence": "MEAAAPPLEACVSRGPSAPEGCRSLSGRGAEGCRARSGGAPGPQGRAARRSAPCRPRSGSGARARRAAAAAGAGARGRGAGRRVPGMEGEKLISATDTQYSSSLLQSLNEQRGHGLFCDVTVIVEDRKFRAHRNILSASSTYFHQLLSVAGQVVELSFVRADIFAEILNYMYSSKIISVRADLIDELIKSGQQLGVKFLADLSVAPSDGRSVPGEVKDGASGTSGSAPTQKDAETQVPAIRQEGREVTGWMPVITESFSLHGIAYETPKITVTDSDDDDDVIFCSEIVPPKECTKDSSAAIQNQPCPNASGASDQKSCGSGGSPLLTSTTSTQKLTSSANQLNPNQTLSSAESLVPVAPQHSTTELILLNRPPVNAPPSVSSSHQTHVPPTIDLVEESQKPSDKGSSTERGTAAVDVEEVVEDSDDVISSSSPSSVSNSSSVQQPSVPKVAPSEGSGVQKKQVVTFPQEQSSKPGEFKIKISDVLSGNNKEFGPGIASKHAGEGQKIITLDTATEIEGLSTGCKVYANIGEDTYDIVIPIKDDPEEGEAKPNEAPRTSDGDSTSRKRMKVKHDDHYELIVDGRVYYICIVCKRSYVCLTSLRRHFNVHSWEKKYPCRYCDKVFPLAEYRTKHEIHHTGERRYQCLTCGKSFINYQIMASHIRSVHSQDPSGDNKLYRLHPCKSLQIRQYAYISDRSSSLPVINENRIVYRVDAAKDGTEGTTSNSPGKQMSWDDIFVPQGNDAIFKQNQSEGSTEFEFVIPESY", "length": 764, "header": "tr|A0A8V0YNX0-1|A0A8V0YNX0_CHICK Isoform 1 of Transcriptional regulator Kaiso OS=Gallus gallus OX=9031 GN=ZBTB33 PE=4 SV=1 CANONICAL=A0A8V0YNX0-1" }, "locus": { "chromosome": "4", "start_pos": 16437217, "end_pos": 16434020, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030757.1", "url": "https://www.ensembl.org/id/ENSGALT00010030757.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017834.1", "url": "https://www.ensembl.org/id/ENSGALP00010017834.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:422367", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422367", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZAN8-1", "protein_name": "Transcriptional regulator Kaiso", "gene_name": "Zbtb33", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MESRKLISATDIQYSASLLNSLNEQRGHGLFCDVTVIVEDRKFRAHRNILSASSTYFHQLFSVAGQVVELSFIRAEIFAEILNYIYSSKIVRVRADLLDELIKSGQLLGVKFIAELGVPLSQVKSISGTVQDGTAETLPSSSNDKSPEIEKSKDEAQDNGAPVMPIITESFSLSAEDYEMKKIIVTDSDDDDDDDVIFCSEILPAKEDLPSNNTATQVQPNPASVAISEVTPCTSSNSPPVTNITPPQLPTPVNQSTLSQAQGSEELLVSSASTHLTPNIILLNQAPLTAPPSVSSSLPNHMSSSVNVLVQNQQAPNSAVTGNKAEEEEEILDDDDDIISSSPDSAVSNTSLVPQADASKSTTFDGSLTQKMQAPILPQEPPSNSLKISDVITRNTNDPGLRSKHVMEGQKIITLDTATEIEGLSTGCKVYANIGEDTYDIVIPVKDDPDGGEAKLENELPKTSGSEPSNKRMKVKHDDHYELIVDGRVYYICIVCKRSYVCLTSLRRHFNIHSWEKKYQCRYCDKVFPLAEYRTKHEIHHTGERRYQCLACGKSFINYQFMSSHIKSVHSQDPSGDSKLYRLHPCKSLQIRQYAYLSNKPSAMPVMKDDAVGYKVDAGKEPPVGTTSAPPQNKSTFWEDIFIQQENDSIFKQNVTDGSTEFEFIIPESY", "length": 670 }, "evidence": [ { "id": "A0A8V0YNX0", "url": "https://omabrowser.org/oma/group/A0A8V0YNX0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1RUB7-1", "protein_name": "Transcriptional regulator Kaiso", "gene_name": "ZBTB33", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MESRKLISATDIQYSGSLLNSLNEQRGHGLFCDVTVIVEDRKFRAHRNILSASSTYFHQLFSVAGQVVELSFIRAEIFAEILNYIYSSKIVRVRSDLLDELIKSGQLLGVKFIAELGVPLSQVKSISGTPQDGNAETLPPGSSDKNLEIQKSKDEAQDNGATIMPIITESFSLSAEDYETKKIIVTDSDDDDDDVIFCSEILPAKETLPSNNAVAQAQPNPGSVAISDVAPCASSSSPPLTSITPPQKLPTSVNQATLSQTQGSEKLLVSSAPTHLTPNIILLNQTPLTNPPNVSSSLPNHMSPSINLLVPNQQPPNNAVLTGNKANEEEEEEIIDDDDDTISSSPDSAVSNTSLVPQAEIPQNTTFDGSLIQKMQVPTLLQEPLSNSLKISDIITRNTNDPGLGSKHLTEGQKIITLDTATEIEGLSTGCKVYANIGEDTYDIVIPVKDDPDEGEARLENEIPKTSSSETANKRMKVKHDDHYELIVDGRVYYICIVCKRSYVCLTSLRRHFNIHSWEKKYPCRYCEKVFPLAEYRTKHEIHHTGERRYQCLACGKSFINYQFMSSHIKSVHSQDPSGDSKLYRLHPCRSLQIRQYAYLSDRSGTMPVMKDDGIGYKVDAGKEPPVGTTSAPQNKPMTWEDIFIQQENDSIFKQNVTDGSTEFEFIIPESY", "length": 672 }, "evidence": [ { "id": "A0A8V0YNX0", "url": "https://omabrowser.org/oma/group/A0A8V0YNX0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q86T24-1", "protein_name": "Transcriptional regulator Kaiso", "gene_name": "ZBTB33", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MESRKLISATDIQYSGSLLNSLNEQRGHGLFCDVTVIVEDRKFRAHKNILSASSTYFHQLFSVAGQVVELSFIRAEIFAEILNYIYSSKIVRVRSDLLDELIKSGQLLGVKFIAELGVPLSQVKSISGTAQDGNTEPLPPDSGDKNLVIQKSKDEAQDNGATIMPIITESFSLSAEDYEMKKIIVTDSDDDDDDVIFCSEILPTKETLPSNNTVAQVQSNPGPVAISDVAPSASNNSPPLTNITPTQKLPTPVNQATLSQTQGSEKLLVSSAPTHLTPNIILLNQTPLSTPPNVSSSLPNHMPSSINLLVQNQQTPNSAILTGNKANEEEEEEIIDDDDDTISSSPDSAVSNTSLVPQADTSQNTSFDGSLIQKMQIPTLLQEPLSNSLKISDIITRNTNDPGVGSKHLMEGQKIITLDTATEIEGLSTGCKVYANIGEDTYDIVIPVKDDPDEGEARLENEIPKTSGSEMANKRMKVKHDDHYELIVDGRVYYICIVCKRSYVCLTSLRRHFNIHSWEKKYPCRYCEKVFPLAEYRTKHEIHHTGERRYQCLACGKSFINYQFMSSHIKSVHSQDPSGDSKLYRLHPCRSLQIRQYAYLSDRSSTIPAMKDDGIGYKVDTGKEPPVGTTTSTQNKPMTWEDIFIQQENDSIFKQNVTDGSTEFEFIIPESY", "length": 672 }, "evidence": [ { "id": "A0A8V0YNX0", "url": "https://omabrowser.org/oma/group/A0A8V0YNX0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8BN78-1", "protein_name": "Transcriptional regulator Kaiso", "gene_name": "Zbtb33", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MESRKLISATDIQYSASLLNSLNEQRGHGLFCDVTVIVEDRKFRAHRNILSASSTYFHQLFSVAGQVVELSFIRAEIFAEILNYIYSSKVVRVRADLLDELIKSGQLLGVKFIAELGVPLSQVKSISGTEQDGTAETLPSSSSDKSLDMEKSKDEAQDNGATVMPIITESFSLSAEDNEMKKIIVTDSDDDDDDDVIFCSEILPAKEDLPSNNTATQVQPNPASVAISEVTPCASNNSPPVTNITPTQLPTPVNQATLSQTQGSEELLVSSASTHLTPNIILLNQAPLTAPPSASSSLPNHMSSSVNVLVQNQQTPNSAVLTGNKAEEEEEIIDDDDDIISSSPDSAVSNTSLVPQADNSKSTTLDGSLTQKMQIPVLPQEPPSNSLKISDVITRNTNDPGLRSKHVMEGQKIITLDTATEIEGLSTGCKVYANIGEDTYDIVIPVKDDPDGGEAKLDNELPKTSGSEPPNKRMKVKHDDHYELIVDGRVYYICIVCKRSYVCLTSLRRHFNIHSWEKKYQCRYCDKVFPLAEYRTKHEIHHTGERRYQCLTCGKSFINYQFMSSHIKSVHSQDPSGDSKLYRLHPCKSLQIRQYAYLSNKSSAMPVMKDDAVGYKVDAGKEPPVGTTSTPPQNKSTFWEDIFIQQENDSIFKQNVTDGSTEFEFIIPESY", "length": 671 }, "evidence": [ { "id": "A0A8V0YNX0", "url": "https://omabrowser.org/oma/group/A0A8V0YNX0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNX0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNX0" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNX0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNX0" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNX0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNX0" } ], "pmid": "" }, { "name": "methyl-CpG binding", "id": "GO:0008327", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008327", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNX0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNX0" } ], "pmid": "" }, { "name": "sequence-specific double-stranded DNA binding", "id": "GO:1990837", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990837", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNX0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNX0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNX0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNX0" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNX0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNX0" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNX0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNX0" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNX0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNX0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNX0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNX0" } ], "pmid": "" }, { "name": "Wnt signaling pathway", "id": "GO:0016055", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016055", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNX0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNX0" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNX0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNX0" } ], "pmid": "" }, { "name": "negative regulation of DNA-templated transcription", "id": "GO:0045892", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045892", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNX0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNX0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 308, "end_pos": 310, "annotation": "n_glycosylation_sequon" }, { "start_pos": 345, "end_pos": 347, "annotation": "n_glycosylation_sequon" }, { "start_pos": 438, "end_pos": 440, "annotation": "n_glycosylation_sequon" }, { "start_pos": 748, "end_pos": 750, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YNX0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNX0" }, { "id": "PS50097", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50097" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "BTB", "eco_id": "ECO_0000259", "start_pos": 118, "end_pos": 176, "start_aa": "Cys", "end_aa": "Ile", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0YNX0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNX0" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 586, "end_pos": 613, "start_aa": "Tyr", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 308, "end_pos": 310 }, { "start_pos": 345, "end_pos": 347 }, { "start_pos": 438, "end_pos": 440 }, { "start_pos": 748, "end_pos": 750 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YQ69-1", "uniprot_ac": "A0A8V0YQ69", "uniprot_id": "A0A8V0YQ69_CHICK", "mass": { "chemical_mass": 71230.0, "monoisotopic_mass": 71230.0 }, "refseq": {}, "gene_names": [ { "name": "ZNF131", "type": "recommended", "evidence": [ { "id": "A0A8V0YQ69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ69" } ] } ], "protein_names": [ { "name": "Zinc finger protein 131", "type": "recommended", "evidence": [ { "id": "A0A8V0YQ69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ69/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQ69", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ69" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ZNF131", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ69", "locus": { "chromosome": "Z", "start_pos": 14162903, "end_pos": 14145561, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010014263", "url": "https://www.ensembl.org/id/ENSGALG00010014263" } ] } } ], "crossref": [ { "id": "A0A8V0YQ69", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YQ69", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd18221", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18221", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "431588", "url": "https://www.ncbi.nlm.nih.gov/gene/431588", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000210", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000210", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011333", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011333", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:431588", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:431588", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "NQMQMEV", "url": "https://omabrowser.org/oma/group/NQMQMEV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YH28", "url": "https://www.orthodb.org/?gene=A0A8V0YH28", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YH33", "url": "https://www.orthodb.org/?gene=A0A8V0YH33", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YQ69", "url": "https://www.orthodb.org/?gene=A0A8V0YQ69", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YV90", "url": "https://www.orthodb.org/?gene=A0A8V0YV90", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24394", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24394", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24394:SF55", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24394:SF55", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00651", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00651", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12874", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12874", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-3899300", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3899300", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YH28", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH28", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YH28-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH28-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YH33", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH33", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YH33-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH33-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQ69", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ69", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQ69-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ69-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YV90", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YV90", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YV90-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YV90-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKCFPCSVWILSEGSFAYAAEVQLCVSTGSFDKPPQVSLSAMEAEEKMECIQEFPEHYKVILDRLNEQREQDQFTDITLIVDGHHFKAHKAVLAACSQFFYRFFQDFTQEPLVEIEGVSNMAFRHLIEFTYTAKLMVQGEEEANDVWKAAEYLQMLEAIKALEIRNKENSSALESNRTEGKTKPKKRKIAETSNVITESLPSAESEPVEIEVEIAEGTIEVEEDSIETLEEVASAEQSIKYIQTTGTSDESALALLADITSKYRQGERKCQIQEKVDSAADPSCKQEHMKTHSTESYKCDICNKRYLRENALKQHLTCYHLDEGGAPKKQRPGKKIHICQYCDKQFDHFGHFKEHLRKHTGEKPFECPNCHERFARNSTLKCHLTACQSGAGAKKGRKKLYECQVCNSVFNSWDQFKDHLVIHTGDKPNHCTLCDLWFMQGSELRRHLKDTHNISERLVTEEVLPVEAVEGEPVTSMTIIEQVEQVHVLPVIQVQVDPAQVTVEQMHQDLIQDNQVKGTQMDELQEQVQISYLEVEHIQTEQGAEVHMEQLHVEHVNQIQMEEVQAELIDGTDLEQVEYESVDQGDPGEKEPSCVDDAGKEVHEQAEDLKTQQLVDIKNQKVDN", "length": 624, "header": "tr|A0A8V0YQ69-1|A0A8V0YQ69_CHICK Isoform 1 of Zinc finger protein 131 OS=Gallus gallus OX=9031 GN=ZNF131 PE=3 SV=1 CANONICAL=A0A8V0YQ69-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YH28-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ69/entry#A0A8V0YH28-1", "sequence": { "sequence": "MEAEEKMECIQEFPEHYKVILDRLNEQREQDQFTDITLIVDGHHFKAHKAVLAACSQFFYRFFQDFTQEPLVEIEGVSNMAFRHLIEFTYTAKLMVQGEEEANDVWKAAEYLQMLEAIKALEIRNKENSSALESNRTEGKTKPKKRKIAETSNVITESLPSAESEPVEIEVEIAEGTIEVEEDSIETLEEVASAEQSIKYIQTTGTSDESALALLADITSKYRQGERKCQIQEKVDSAADPSCKQVEGIEIVELQLSHMNNLFHCEKCNRSFKLFYHFKEHMKTHSTESYKCDICNKRYLRENALKQHLTCYHLDEGGAPKKQRPGKKIHICQYCDKQFDHFGHFKEHLRKHTGEKPFECPNCHERFARNSTLKCHLTACQSGAGAKKGRKKLYECQVCNSVFNSWDQFKDHLVIHTGDKPNHCTLCDLWFMQGSELRRHLKDTHNISERLVTEEVLPVEAVEGEPVTSMTIIEQVEQVHVLPVIQVQVDPAQVTVEQMHQDLIQDNQVKGTQMDELQEQVQISYLEVEHIQTEQGAEVHMEQLHVEHVNQIQMEEVQAELIDGTDLEQVEYESVDQGDPGEKEPSCVDDAGKEVHEQAEDLKTQQLVDIKNQKVDN", "length": 617, "header": "tr|A0A8V0YH28-1|A0A8V0YQ69_CHICK Computationally mapped isoform of Zinc finger protein 131 OS=Gallus gallus OX=9031 GN=ZNF131 PE=3 SV=1 CANONICAL=A0A8V0YQ69-1" }, "locus": { "chromosome": "Z", "start_pos": 14160791, "end_pos": 14149107, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034349.1", "url": "https://www.ensembl.org/id/ENSGALT00010034349.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020175.1", "url": "https://www.ensembl.org/id/ENSGALP00010020175.1" } ] } }, { "isoform_ac": "A0A8V0YH33-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ69/entry#A0A8V0YH33-1", "sequence": { "sequence": "MEAEEKMECIQEFPEHYKVILDRLNEQREQDQFTDITLIVDGHHFKAHKAVLAACSQFFYRFFQDFTQEPLVEIEGVSNMAFRHLIEFTYTAKLMVQGEEEANDVWKAAEYLQMLEAIKALEIRNKENSSALESNRTEGKTKPKKRKIAETSNVITESLPSAESEPVEIEVEIAEGTIEVEEDSIETLEEVASAEQSIKYIQTTGTSDESALALLADITSKYRQGERKCQIQEKVDSAADPSCKQEHMKTHSTESYKCDICNKRYLRENALKQHLTCYHLDEGGAPKKQRPGKKIHICQYCDKQFDHFGHFKEHLRKHTGEKPFECPNCHERFARNSTLKCHLTACQSGAGAKKGRKKLYECQVCNSVFNSWDQFKDHLVIHTGDKPNHCTLCDLWFMQGSELRRHLKDTHNISERLVTEEVLPVEAVEGEPVTSMTIIEQVEQVHVLPVIQVQVDPAQVTVEQMHQDLIQDNQVKGTQMDELQEQVQISYLEVEHIQTEQGAEVHMEQLHVEHVNQIQMEEVQAELIDGTDLEQVEYESVDQGDPGEKEPSCVDDAGKEVHEQAEDLKTQQLVDIKNQKVDN", "length": 583, "header": "tr|A0A8V0YH33-1|A0A8V0YQ69_CHICK Computationally mapped isoform of Zinc finger protein 131 OS=Gallus gallus OX=9031 GN=ZNF131 PE=3 SV=1 CANONICAL=A0A8V0YQ69-1" }, "locus": { "chromosome": "Z", "start_pos": 14160791, "end_pos": 14149107, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034355.1", "url": "https://www.ensembl.org/id/ENSGALT00010034355.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020180.1", "url": "https://www.ensembl.org/id/ENSGALP00010020180.1" } ] } }, { "isoform_ac": "A0A8V0YQ69-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ69/entry#A0A8V0YQ69-1", "sequence": { "sequence": "MKCFPCSVWILSEGSFAYAAEVQLCVSTGSFDKPPQVSLSAMEAEEKMECIQEFPEHYKVILDRLNEQREQDQFTDITLIVDGHHFKAHKAVLAACSQFFYRFFQDFTQEPLVEIEGVSNMAFRHLIEFTYTAKLMVQGEEEANDVWKAAEYLQMLEAIKALEIRNKENSSALESNRTEGKTKPKKRKIAETSNVITESLPSAESEPVEIEVEIAEGTIEVEEDSIETLEEVASAEQSIKYIQTTGTSDESALALLADITSKYRQGERKCQIQEKVDSAADPSCKQEHMKTHSTESYKCDICNKRYLRENALKQHLTCYHLDEGGAPKKQRPGKKIHICQYCDKQFDHFGHFKEHLRKHTGEKPFECPNCHERFARNSTLKCHLTACQSGAGAKKGRKKLYECQVCNSVFNSWDQFKDHLVIHTGDKPNHCTLCDLWFMQGSELRRHLKDTHNISERLVTEEVLPVEAVEGEPVTSMTIIEQVEQVHVLPVIQVQVDPAQVTVEQMHQDLIQDNQVKGTQMDELQEQVQISYLEVEHIQTEQGAEVHMEQLHVEHVNQIQMEEVQAELIDGTDLEQVEYESVDQGDPGEKEPSCVDDAGKEVHEQAEDLKTQQLVDIKNQKVDN", "length": 624, "header": "tr|A0A8V0YQ69-1|A0A8V0YQ69_CHICK Isoform 1 of Zinc finger protein 131 OS=Gallus gallus OX=9031 GN=ZNF131 PE=3 SV=1 CANONICAL=A0A8V0YQ69-1" }, "locus": { "chromosome": "Z", "start_pos": 14160791, "end_pos": 14148308, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034338.1", "url": "https://www.ensembl.org/id/ENSGALT00010034338.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020168.1", "url": "https://www.ensembl.org/id/ENSGALP00010020168.1" } ] } }, { "isoform_ac": "A0A8V0YV90-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ69/entry#A0A8V0YV90-1", "sequence": { "sequence": "MEAEEKMECIQEFPEHYKVILDRLNEQREQDQFTDITLIVDGHHFKAHKAVLAACSQFFYRFFQDFTQEPLVEIEGVSNMAFRHLIEFTYTAKLMVQGEEEANDVWKAAEYLQMLEAIKALEIRNKENSSALESNRTEGKTKPKKRKIAETSNVITESLPSAESEPVEIEVEIAEGTIEVEEDSIETLEEVASAEQSIKYIQTTGTSDESALALLADITSKYRQGERKCQIQEKVDSAADPSCKQEHMKTHSTESYKCDICNKRYLRENALKQHLTCYHLDEGGAPKKQRPGKKIHICQYCDKQFDHFGHFKEHLRKHTGEKPFECPNCHERFARNSTLKCHLTACQSGAGAKKGRKKLYECQVCNSVFNSWDQFKDHLVIHTGDKPNHCTLCDLWFMQGSELRRHLKDTHNISERLVTEEVLPVEAVEGEPVTSMTIIEQVEQVHVLPVIQVQVDPAQVTVEQMHQDLIQDNQVKGTQMDELQEQVQISYLEVEHIQTEQGAEVHMEQLHVEHVNQIQMEEVQAELIDGTDLEQVEYESVDQGDPGEKEPSCVDDAEANCCYRFAGCL", "length": 569, "header": "tr|A0A8V0YV90-1|A0A8V0YV90_CHICK Computationally mapped isoform of Zinc finger protein 131 OS=Gallus gallus OX=9031 GN=ZNF131 PE=3 SV=1 CANONICAL=A0A8V0YQ69-1" }, "locus": { "chromosome": "Z", "start_pos": 14161160, "end_pos": 14149107, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034344.1", "url": "https://www.ensembl.org/id/ENSGALT00010034344.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020171.1", "url": "https://www.ensembl.org/id/ENSGALP00010020171.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:431588", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:431588", "resource": "KEGG Pathway" }, { "id": "R-GGA-3899300", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3899300", "resource": "Reactome", "description": "SUMOylation of transcription cofactors" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2JX21-1", "protein_name": "Zinc finger protein 131", "gene_name": "Zfp131", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEAEETMECLQEFPEHHKMILDRLNEQREQDRFTDITLIVDGHHFKAHKAVLAACSKFFYKFFQEFTQEPLVEIEGVSKMAFRHLIEFTYTAKLMIQGEEEANDVWKAAEFLQMLEAIKALEVRNKENSAPLEETTTGKNEAKKRKIAETSNVITESLPSAESEPVEIEVEIAEGTIEVEDEGIAALEEMASGKQSIKYIQSTGSSDDSALALLADITSKYRPGESKGQISEDDCASDPISKQEHMKSHSTESFKCEICNKRYLRESAWKHHLNCYHLEEGGVSKKQRTGKKIHTCQYCEKQFDHFGHFKEHLRKHTGEKPFECSNCHERFARNSTLKCHLTACQTGVGAKKGRKKLYECQVCNSVFNSWDQFKDHLVIHTGDKPNHCTLCDLWFMQGNELRRHLSDAHNISERIVTEEVLSVETHLQTEPVTSMTIIEQVGKVHVLPLLQVQVDSAQVTVEQVHPDLLQDGQVHDSQMSALPEQVQVSYLEVGRIQTEEGTEVHVEELHVERVNQMPVEVQTELLEADLDHMTPEMMSQEESEPNHADAAMEEYEDTEGLETKPGEHSHAVKVDHDRTSMPVLE", "length": 585 }, "evidence": [ { "id": "A0A8V0YQ69", "url": "https://omabrowser.org/oma/group/A0A8V0YQ69/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A2R8QJR9-1", "protein_name": "Zinc finger protein 131", "gene_name": "znf131", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSVDGDVDYGHEFPAHYKVMLDKLNEQRQLDQFTDITLIVDGHQFRAHKAVLAACSQFFHKFFQDFTQEPLVEIEGVSNSAFRHLMEFTYTATLAVNGEEEVSDVWRAAEYLQMQEAIKALNNRRNGTTSPQPGKSKAKKRKISETSNVITESLPSADTEAVEIEVEVGEEHIEVEESGLVEVVDVARGTTVPSSDDSALALLADITSKYQQGEQTLHVIKKVDETVVVQEEAVVASKTLENIEVVEVQISQLDNLFRCDKCDRCFKLYYHLKQHMKTHIASPERGFVCRHCGKAYAREGALKQHLNNYHFDAEEQSRRQKKKVHVCEYCEKQFDHFGHFKEHLRKHTGEKPFECPECHERFARNSTLKCHMSACQNGSGAKKGRKKLYECQVCSSVFNSWEQFKDHLVTHTGEKPNHCTLCDLWFTSPRDLHTHLQEHHSLQEKVIVAEDILISDPANVLSMEEGEERVILEDGIRVEHVTVEPVDVVAVEETLVVEEETQIQPSQPEGGVAETVVLQVDSEKLKEQVMGIQVERETVAEPAEAKQEPASCEKTENV", "length": 558 }, "evidence": [ { "id": "A0A8V0YQ69", "url": "https://omabrowser.org/oma/group/A0A8V0YQ69/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "G3HMY2-1", "protein_name": "Zinc finger protein 131", "gene_name": "Znf131", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MEAEETMECLQEFPEHHKMILDRLNEQREQDRFTDITLIVDGHHFKAHKAVLAACSKFFYKFFQEFTQEPLVEIEGVSKMAFRHLIEFTYTAKLMIQGEEEANDVWKAAEFLQMLEAIKALEVRNKENSAPLEENTTGKNEAKKRKIAETSNVITESLPSAESEPVEIEVEIAEGTIEVEDDTMETLEEVASTKQSIKYIQSTGSSDDSALALLADITSKYRQGESKEQISEDDCASDPISKQVEGIEIVELQLSHVKDLFHCEKCNRSFKLFYHFKEHMKSHSTESYKCEICNKRYLRESAWKQHLNCYHLEEGGVSKKQRTGKKIHICQYCDKQFDHFGHFKEHLRKHTGEKPFECSNCHERFARNSTLKCHLTACQTGVGAKKGRKKLYECQVCNSVFNSWDQFKDHLVIHTGDKPNHCTLCDLWFMQGNELRRHLSDAHNISERIVTEEVLSVETRVQTEPVTSMTIIEQVGKVHVLPLLQVQVDSAQVTVEQVHPDLLQDGQVHDSPMSELPEQVQVSYLEVGRIQTEEGTEVHVEELHVERVNQMPVEVQTELLEADLDHMTPEIMSQEESEPSHADAAEAAVEDHEDAEGLETKPREYSQAGKAEDDRTSVPVLE", "length": 622 }, "evidence": [ { "id": "A0A8V0YQ69", "url": "https://omabrowser.org/oma/group/A0A8V0YQ69/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P52739-1", "protein_name": "Zinc finger protein 131", "gene_name": "ZNF131", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEAEETMECLQEFPEHHKMILDRLNEQREQDRFTDITLIVDGHHFKAHKAVLAACSKFFYKFFQEFTQEPLVEIEGVSKMAFRHLIEFTYTAKLMIQGEEEANDVWKAAEFLQMLEAIKALEVRNKENSAPLEENTTGKNEAKKRKIAETSNVITESLPSAESEPVEIEVEIAEGTIEVEDEGIETLEEVASAKQSVKYIQSTGSSDDSALALLADITSKYRQGDRKGQIKEDGCPSDPTSKQVEGIEIVELQLSHVKDLFHCEKCNRSFKLFYHFKEHMKSHSTESFKCEICNKRYLRESAWKQHLNCYHLEEGGVSKKQRTGKKIHVCQYCEKQFDHFGHFKEHLRKHTGEKPFECPNCHERFARNSTLKCHLTACQTGVGAKKGRKKLYECQVCNSVFNSWDQFKDHLVIHTGDKPNHCTLCDLWFMQGNELRRHLSDAHNISERLVTEEVLSVETRVQTEPVTSMTIIEQVGKVHVLPLLQVQVDSAQVTVEQVHPDLLQDSQVHDSHMSELPEQVQVSYLEVGRIQTEEGTEVHVEELHVERVNQMPVEVQTELLEADLDHVTPEIMNQEERESSQADAAEAAREDHEDAEDLETKPTVDSEAEKAENEDRTALPVLE", "length": 623 }, "evidence": [ { "id": "A0A8V0YQ69", "url": "https://omabrowser.org/oma/group/A0A8V0YQ69/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8K3J5-1", "protein_name": "Zinc finger protein 131", "gene_name": "Znf131", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEAEETMECLQEFPEHHKMILDRLNEQREQDRFTDITLIVDGHHFKAHKAVLAACSKFFYKFFQEFTQEPLVEIEGVSKMAFRHLIEFTYTAKLMIQGEEEANDVWKAAEFLQMLEAIKALEVRNKENSAPLEENTTGKNEAKKRKIAETSNVITESLPSAESEPVEIEVEIAEGTIEVEDEGIEALEEMASAKQSIKYIQSTGSSDDSALALLADITSKYRQGESKGQISEDDCASDPISKQVEGIEIVELQLSHVKDLFHCEKCNRSFKLFYHFKEHMKSHSTESFKCEICNKRYLRESAWKQHLNCYHLEEGGVSKKQRTGKKIHICQYCDKQFDHFGHFKEHLRKHTGEKPFECSNCHERFARNSTLKCHLTACQTGVGAKKGRKKLYECQVCNSVFNSWDQFKDHLVIHTGDKPNHCTLCDLWFMQGNELRRHLSDAHNISERIVTEEVLSVETHLQTEPVTSMTIIEQVGKVHVLPLLQVQVDSAQVTVEQVHPDLLQDSQVHDSQMTGLPEQVQVSYLEVGRIQTEEGTEVHVEELHVERVNQMPVEVQTELLEADLDHMTPEIMSQEEREPNHADAAMEEHEDAEGLETKPSEYSQARKTENDRTSLPVLE", "length": 619 }, "evidence": [ { "id": "A0A8V0YQ69", "url": "https://omabrowser.org/oma/group/A0A8V0YQ69/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQ69", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ69" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQ69", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ69" } ], "pmid": "" }, { "name": "DNA-binding transcription repressor activity, RNA polymerase II-specific", "id": "GO:0001227", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001227", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQ69", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ69" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQ69", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ69" } ], "pmid": "" }, { "name": "DNA-binding transcription activator activity, RNA polymerase II-specific", "id": "GO:0001228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001228", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQ69", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ69" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQ69", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ69" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQ69", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ69" } ], "pmid": "" }, { "name": "intermediate filament cytoskeleton", "id": "GO:0045111", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045111", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQ69", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ69" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQ69", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ69" } ], "pmid": "" }, { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQ69", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ69" } ], "pmid": "" }, { "name": "regulation of immune system process", "id": "GO:0002682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002682", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQ69", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ69" } ], "pmid": "" }, { "name": "regulation of cytokine production", "id": "GO:0001817", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001817", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQ69", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ69" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 169, "end_pos": 171, "annotation": "n_glycosylation_sequon" }, { "start_pos": 176, "end_pos": 178, "annotation": "n_glycosylation_sequon" }, { "start_pos": 377, "end_pos": 379, "annotation": "n_glycosylation_sequon" }, { "start_pos": 453, "end_pos": 455, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YQ69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ69" }, { "id": "PS50097", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50097" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "BTB", "eco_id": "ECO_0000259", "start_pos": 75, "end_pos": 139, "start_aa": "Thr", "end_aa": "Gly", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0YQ69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ69" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 297, "end_pos": 325, "start_aa": "Tyr", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 169, "end_pos": 171 }, { "start_pos": 176, "end_pos": 178 }, { "start_pos": 377, "end_pos": 379 }, { "start_pos": 453, "end_pos": 455 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YNC3-1", "uniprot_ac": "A0A8V0YNC3", "uniprot_id": "A0A8V0YNC3_CHICK", "mass": { "chemical_mass": 284095.0, "monoisotopic_mass": 284095.0 }, "refseq": {}, "gene_names": [ { "name": "ZNF462", "type": "recommended", "evidence": [ { "id": "A0A8V0YNC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNC3" } ] } ], "protein_names": [ { "name": "Zinc finger protein 462", "type": "recommended", "evidence": [ { "id": "A0A8V0YNC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNC3/entry#names_and_taxonomy" } ] }, { "name": "Zinc finger PBX1-interacting protein", "type": "synonym", "evidence": [ { "id": "A0A8V0YNC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNC3/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Zinc finger nuclear factor involved in transcription by regulating chromatin structure and organization. Involved in the pluripotency and differentiation of embryonic stem cells by regulating SOX2, POU5F1/OCT4, and NANOG. By binding PBX1, prevents the heterodimerization of PBX1 and HOXA9 and their binding to DNA. Regulates neuronal development and neural cell differentiation.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YH43", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH43#function" }, { "database": "UniProtKB", "id": "ARBA00057412", "url": "https://www.uniprot.org/uniprotkb/ARBA00057412#function" }, { "database": "UniProtKB", "id": "A0A8V0YNC3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNC3#function" }, { "database": "UniProtKB", "id": "A0A8V0YND1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YND1#function" }, { "database": "UniProtKB", "id": "A0A8V0YNG7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNG7#function" }, { "database": "UniProtKB", "id": "A0A8V0YNH2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNH2#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNC3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNC3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ZNF462", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNC3", "locus": { "chromosome": "Z", "start_pos": 56239424, "end_pos": 56150642, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010014265", "url": "https://www.ensembl.org/id/ENSGALG00010014265" } ] } } ], "crossref": [ { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050688", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050688", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057830", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057830", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057831", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057831", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057832", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057832", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR059058", "url": "https://www.ebi.ac.uk/interpro/entry/IPR059058", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR059059", "url": "https://www.ebi.ac.uk/interpro/entry/IPR059059", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YH43", "url": "https://www.orthodb.org/?gene=A0A8V0YH43", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YNC3", "url": "https://www.orthodb.org/?gene=A0A8V0YNC3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YND1", "url": "https://www.orthodb.org/?gene=A0A8V0YND1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YNG7", "url": "https://www.orthodb.org/?gene=A0A8V0YNG7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YNH2", "url": "https://www.orthodb.org/?gene=A0A8V0YNH2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YQ73", "url": "https://www.orthodb.org/?gene=A0A8V0YQ73", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24403", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24403", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24403:SF105", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24403:SF105", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24403:SF58", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24403:SF58", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13894", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13894", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23075", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23075", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23077", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23077", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23223", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23223", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23224", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23224", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23225", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23225", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YH43", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH43", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YH43-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH43-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YNC3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNC3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YNC3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNC3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YND1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YND1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YND1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YND1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YNG7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNG7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YNG7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNG7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YNH2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNH2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YNH2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNH2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQ73", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ73", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQ73-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ73-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEVLQCDGCDFRAPSYEDLKAHIQDVHTAFLQPTDVSEESPSQPRSGSMNASNQTEVEFSSVKDEFTIADEIAGQNATSQMGTGSYYSQSQTFYGQHMAPNPKPTNKFFQCKFCVRYFRSKNLLIEHTRKVHGAQAGGSSVGPPSASSLNYNIMMHEGFGKVFSCQFCTYKSPRRARIIKHQKMYHKNNLKESSTPPAASTAISESTSASVPVQEPCKELPAEVVERSILESMVKPLTKSRGNFCCEWCSYQTPRRERWCDHMMKKHRSMVKILSSLRQQQEGTSAPDVQNKSAQNASPNSNYISMNTTGREMSNANVSNFRSSMGNSLIRPNSSTSSKFSSVSYPQMKPKSPHNSSIVNLSDRSRYGIADMTNSSADLETNSMLNDSSSDEELNEMDSENGLNSMDHQTTGMSAEQLMGSDGNKLLETKGIPFRRYMNRFQCPFCPFLTMHRRSISRHIENIHLSGKTAVYKCDECPFTCKSSLKLGAHKQCHTGTTSDWDTVNSQAESIASSLNDSTVSYESGNINGRKSAGMMEPVQQQQQQQQQQQSPQPHSQHPYKCTMCNYSTTTLKGLRVHQQHKHSFCDNLPKYDGPPSNTPQESEADAHTSASTVKKSQTSILGLSSKNNFVAKAPRKVSNDFPLDLSPVKKRTRIDEIASNLQSKISQNKQQEDAVINVEDDEEEEEDNEVEIEVELDREEEQTEPMIEVSSSYAPQQMWGREANDSQKETNFRSLQHDYNSANGAEIELTLSEDEEDYYSSVSMKEHQSPNASVLGGQSNMYGTDQNNENAEFSDSGRLYYCKHCDFSNKSARSVSTHYQRMHPYIKFSFRYILDPNDHSAVYRCLECYIDYTNFEDLQQHYGEHHPEAMNVLNFDHSDLIYRCRFCSYTSPNVRSLMPHYQRMHPTVKINNAMIFSSYVVEQQEGLNTESQTLREILNSAPKTMATSTPVARGAGVPAGFNKSAAKSFSPECENQKEPSVNSVVVYDCDVCSFASPNMHSVLVHYQKKHPEEKASYFRIQKTMRVVSVDRGSALAQMSFEMGTPVSPKLSNLASPPPPPPPPDLATELYYCKHCSYSNRSVVGVLVHYQKRHPEIKVTAKYIRQAPPTAAMMRAGELPPGIQRPPVSMQQLSRGGSETSVNPPENEMFFCQHCDYGNRTVKGVLIHYQKKHRDFKANADVIRQHTATIRSLCDRSQKKSSGSVSAHTSSTERDKSKLRALKCRQCSYTSPYFYALRKHIKKDHPNLKATVTSILRWAFLDGLIEAGYHCEWCIYSHTEPSGLLVHYQRRHPEHYVDYTYMATKLWAGPDPSPPALVLPAEAKTYKCRDCIFEASSIWDITNHYQAFHPWAMNGDESVLLDIIKEKDAAEKSGTQPDEAGVRMDSEDQITTSQMDQEPECAEDPSLSQEKTVQLASANPAISSTPYQCTVCQSEYNNLHGLLTHYGKKHPGMKVKAADFAQDIDINPGAVYKCRHCPYINTRIHGVLTHYQKRHPSIKVTAEDFVHDVEQSTDIAQNDVEETSRIFKQGYGAYRCKLCPYTHGTLEKLKIHYEKYHNQPEFDVFAQSPPKVSASLEPDMVTEIKASPEIAAEDVGEISVAAPHFSSSHLVSHTVFRCQLCKYFCSTRKGIARHYRIKHNNVRAQPEGKNNLFKCALCSYTNPIRKGLAAHYQKRHDIDAYYTHCLAASRTVSDKPNKVIIPSPPKDDTPQLSEELRRAVEKKKCSLCSFQSFSKKGIVSHYMKRHPGVFPKKQHASKLGGYFTAVYADEHEKLTPAEERNEFEKPEVESEAQEIEWLPFRCIKCFKLSFSTAELLCMHYTDHHSKDLKRDFTILGSGTRSQNAVYQCKHCDMKLHSTAELTAHLNGHNEEFQKRAKRQERRKQLLSKQKYADGAFADFKQERAFGHLEDVSKLKERKVVGYKCKFCVEVHPTLRAICNHLRKHVQYGNVSSVSATVKQEAEDSSNTTLEGFEGAKDPGILEFAEAESGASLEDETRPGGYHCSQCDRVLMSMQGLRSHERSHLALAMFTREDKYSCQYCSFVSAFRHNLDRHMQTHHGHHKPFRCKLCPFKSSYNSRLKTHILKAHAGEHAYKCSSCSFSTMTISQLKEHSLKVHGKALTLPRPRIVNLAASHAHHTSKNHTPAEEVEDSNDSSYSEPPDVQQQLNHYQSAALARNNNVSPIPLSGSAAGMEKTEAILNCEFCEFSSGYIQSIRRHYRDKHGGKKLFKCKDCSFYTGFKSAFTMHVEAGHSAVPEEGPKDLRCPLCLYHTKYKRNMIDHIVLHREERVVPIEVCRSKLSKYLQGVVFRCDKCTFTCSSDESLQQHIEKHNELKPYKCQLCYYETKHTEELDAHLRDEHKVSRNFELVGRVNLDQLEQMKGKTESSSSDEEEKEEELSPKTEERDSMMFPDSGPPEKRFPCEFCGRSFTEGSEWERHVLRHGMALNESKHGTSEDSQPKEDVEETVSTLPEEKEGIEKMVLDYSHNSETVVSVVTPDKPLQENSEAKNE", "length": 2509, "header": "tr|A0A8V0YNC3-1|A0A8V0YNC3_CHICK Isoform 1 of Zinc finger protein 462 OS=Gallus gallus OX=9031 GN=ZNF462 PE=1 SV=1 CANONICAL=A0A8V0YNC3-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YH43-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNC3/entry#A0A8V0YH43-1", "sequence": { "sequence": "MEVLQCDGCDFRAPSYEDLKAHIQDVHTAFLQPTDVSEESPSQPRSGSMNASNQTEVEFSSVKDEFTIADEIAVQEPCKELPAEVVERSILESMVKPLTKSRGNFCCEWCSYQTPRRERWCDHMMKKHRSMVKILSSLRQQQEGTSAPDVQNKSAQNASPNSNYISMNTTGREMSNANVSNFRSSMGNSLIRPNSSTSSKFSSVSYPQMKPKSPHNSSIVNLSDRSRYGIADMTNSSADLETNSMLNDSSSDEELNEMDSENGLNSMDHQTTGMSAEQLMGSDGNKLLETKGIPFRRYMNRFQCPFCPFLTMHRRSISRHIENIHLSGKTAVYKCDECPFTCKSSLKLGAHKQCHTGTTSDWDTVNSQAESIASSLNDSTVSYESGNINGRKSAGMMEPVQQQQQQQQQQQSPQPHSQHPYKCTMCNYSTTTLKGLRVHQQHKHSFCDNLPKYDGPPSNTPQESEADAHTSASTVKKSQTSILGLSSKNNFVAKAPRKVSNDFPLDLSPVKKRTRIDEIASNLQSKISQNKQQEDAVINVEDDEEEEEDNEVEIEVELDREEEQTEPMIEVSSSYAPQQMWGREANDSQKETNFRSLQHDYNSANGAEIELTLSEDEEDYYSSVSMKEHQSPNASVLGGQSNMYGTDQNNENAEFSDSGRLYYCKHCDFSNKSARSVSTHYQRMHPYIKFSFRYILDPNDHSAVYRCLECYIDYTNFEDLQQHYGEHHPEAMNVLNFDHSDLIYRCRFCSYTSPNVRSLMPHYQRMHPTVKINNAMIFSSYVVEQQEGLNTESQTLREILNSAPKTMATSTPVARGAGVPAGFNKSAAKSFSPECENQKEPSVNSVVVYDCDVCSFASPNMHSVLVHYQKKHPEEKASYFRIQKTMRVVSVDRGSALAQMSFEMGTPVSPKLSNLASPPPPPPPPDLATELYYCKHCSYSNRSVVGVLVHYQKRHPEIKVTAKYIRQAPPTAAMMRAGELPPGIQRPPVSMQQLSRGGSETSVNPPENEMFFCQHCDYGNRTVKGVLIHYQKKHRDFKANADVIRQHTATIRSLCDRSQKKSSGSVSAHTSSTERDKSKLRALKCRQCSYTSPYFYALRKHIKKDHPNLKATVTSILRWAFLDGLIEAGYHCEWCIYSHTEPSGLLVHYQRRHPEHYVDYTYMATKLWAGPDPSPPALVLPAEAKTYKCRDCIFEASSIWDITNHYQAFHPWAMNGDESVLLDIIKEKDAAEKSGTQPDEAGVRMDSEDQITTSQMDQEPECAEDPSLSQEKTVQLASANPAISSTPYQCTVCQSEYNNLHGLLTHYGKKHPGMKVKAADFAQDIDINPGAVYKCRHCPYINTRIHGVLTHYQKRHPSIKVTAEDFVHDVEQSTDIAQNDVEETSRIFKQGYGAYRCKLCPYTHGTLEKLKIHYEKYHNQPEFDVFAQSPPKVSASLEPDMVTEIKASPEIAAEDVGEISVAAPHFSSSHLVSHTVFRCQLCKYFCSTRKGIARHYRIKHNNVRAQPEGKNNLFKCALCSYTNPIRKGLAAHYQKRHDIDAYYTHCLAASRTVSDKPNKVIIPSPPKDDTPQLSEELRRAVEKKKCSLCSFQSFSKKGIVSHYMKRHPGVFPKKQHASKLGGYFTAVYADEHEKLTPAEERNEFEKPEVESEAQEIEWLPFRCIKCFKLSFSTAELLCMHYTDHHSKDLKRDFTILGSGTRSQNAVYQCKHCDMKLHSTAELTAHLNGHNEEFQKRAKRQERRKQLLSKQKYADGAFADFKQERAFGHLEDVSKLKERKVVGYKCKFCVEVHPTLRAICNHLRKHVQYGNVSSVSATVKGLRSHERSHLALAMFTREDKYSCQYCSFVSAFRHNLDRHMQTHHGHHKPFRCKLCPFKSSYNSRLKTHILKAHADSSYSEPPDVQQQLNHYQSAALARNNNVSPIPLSGSAAGMEKTEAILNCEFCEFSSGYIQSIRRHYRDKHGGKKLFKCKDCSFYTGFKSAFTMHVEAGHSAVPEEGPKDLRCPLCLYHTKYKRNMIDHIVLHREERVVPIEVCRSKLSKYLQGVVFRCDKCTFTCSSDESLQQHIEKHNELKPYKCQLCYYETKHTEELDAHLRDEHKVSRNFELVGRVNLDQLEQMKGKTESSSSDEEEKEEELSPKTEERDSMMFPDSGPPEKRFPCEFCGRSFTEGSEWERHVLRHGMALNESKHGTSEDSQPKEDVEETVSTLPEEKEGIEKMVLDYSHNSETVVSVVTPDKPLQENSEAKNE", "length": 2250, "header": "tr|A0A8V0YH43-1|A0A8V0YNC3_CHICK Computationally mapped isoform of Zinc finger protein 462 OS=Gallus gallus OX=9031 GN=ZNF462 PE=1 SV=1 CANONICAL=A0A8V0YNC3-1" }, "locus": { "chromosome": "Z", "start_pos": 56238797, "end_pos": 56188794, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034376.1", "url": "https://www.ensembl.org/id/ENSGALT00010034376.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020190.1", "url": "https://www.ensembl.org/id/ENSGALP00010020190.1" } ] } }, { "isoform_ac": "A0A8V0YNC3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNC3/entry#A0A8V0YNC3-1", "sequence": { "sequence": "MEVLQCDGCDFRAPSYEDLKAHIQDVHTAFLQPTDVSEESPSQPRSGSMNASNQTEVEFSSVKDEFTIADEIAGQNATSQMGTGSYYSQSQTFYGQHMAPNPKPTNKFFQCKFCVRYFRSKNLLIEHTRKVHGAQAGGSSVGPPSASSLNYNIMMHEGFGKVFSCQFCTYKSPRRARIIKHQKMYHKNNLKESSTPPAASTAISESTSASVPVQEPCKELPAEVVERSILESMVKPLTKSRGNFCCEWCSYQTPRRERWCDHMMKKHRSMVKILSSLRQQQEGTSAPDVQNKSAQNASPNSNYISMNTTGREMSNANVSNFRSSMGNSLIRPNSSTSSKFSSVSYPQMKPKSPHNSSIVNLSDRSRYGIADMTNSSADLETNSMLNDSSSDEELNEMDSENGLNSMDHQTTGMSAEQLMGSDGNKLLETKGIPFRRYMNRFQCPFCPFLTMHRRSISRHIENIHLSGKTAVYKCDECPFTCKSSLKLGAHKQCHTGTTSDWDTVNSQAESIASSLNDSTVSYESGNINGRKSAGMMEPVQQQQQQQQQQQSPQPHSQHPYKCTMCNYSTTTLKGLRVHQQHKHSFCDNLPKYDGPPSNTPQESEADAHTSASTVKKSQTSILGLSSKNNFVAKAPRKVSNDFPLDLSPVKKRTRIDEIASNLQSKISQNKQQEDAVINVEDDEEEEEDNEVEIEVELDREEEQTEPMIEVSSSYAPQQMWGREANDSQKETNFRSLQHDYNSANGAEIELTLSEDEEDYYSSVSMKEHQSPNASVLGGQSNMYGTDQNNENAEFSDSGRLYYCKHCDFSNKSARSVSTHYQRMHPYIKFSFRYILDPNDHSAVYRCLECYIDYTNFEDLQQHYGEHHPEAMNVLNFDHSDLIYRCRFCSYTSPNVRSLMPHYQRMHPTVKINNAMIFSSYVVEQQEGLNTESQTLREILNSAPKTMATSTPVARGAGVPAGFNKSAAKSFSPECENQKEPSVNSVVVYDCDVCSFASPNMHSVLVHYQKKHPEEKASYFRIQKTMRVVSVDRGSALAQMSFEMGTPVSPKLSNLASPPPPPPPPDLATELYYCKHCSYSNRSVVGVLVHYQKRHPEIKVTAKYIRQAPPTAAMMRAGELPPGIQRPPVSMQQLSRGGSETSVNPPENEMFFCQHCDYGNRTVKGVLIHYQKKHRDFKANADVIRQHTATIRSLCDRSQKKSSGSVSAHTSSTERDKSKLRALKCRQCSYTSPYFYALRKHIKKDHPNLKATVTSILRWAFLDGLIEAGYHCEWCIYSHTEPSGLLVHYQRRHPEHYVDYTYMATKLWAGPDPSPPALVLPAEAKTYKCRDCIFEASSIWDITNHYQAFHPWAMNGDESVLLDIIKEKDAAEKSGTQPDEAGVRMDSEDQITTSQMDQEPECAEDPSLSQEKTVQLASANPAISSTPYQCTVCQSEYNNLHGLLTHYGKKHPGMKVKAADFAQDIDINPGAVYKCRHCPYINTRIHGVLTHYQKRHPSIKVTAEDFVHDVEQSTDIAQNDVEETSRIFKQGYGAYRCKLCPYTHGTLEKLKIHYEKYHNQPEFDVFAQSPPKVSASLEPDMVTEIKASPEIAAEDVGEISVAAPHFSSSHLVSHTVFRCQLCKYFCSTRKGIARHYRIKHNNVRAQPEGKNNLFKCALCSYTNPIRKGLAAHYQKRHDIDAYYTHCLAASRTVSDKPNKVIIPSPPKDDTPQLSEELRRAVEKKKCSLCSFQSFSKKGIVSHYMKRHPGVFPKKQHASKLGGYFTAVYADEHEKLTPAEERNEFEKPEVESEAQEIEWLPFRCIKCFKLSFSTAELLCMHYTDHHSKDLKRDFTILGSGTRSQNAVYQCKHCDMKLHSTAELTAHLNGHNEEFQKRAKRQERRKQLLSKQKYADGAFADFKQERAFGHLEDVSKLKERKVVGYKCKFCVEVHPTLRAICNHLRKHVQYGNVSSVSATVKQEAEDSSNTTLEGFEGAKDPGILEFAEAESGASLEDETRPGGYHCSQCDRVLMSMQGLRSHERSHLALAMFTREDKYSCQYCSFVSAFRHNLDRHMQTHHGHHKPFRCKLCPFKSSYNSRLKTHILKAHAGEHAYKCSSCSFSTMTISQLKEHSLKVHGKALTLPRPRIVNLAASHAHHTSKNHTPAEEVEDSNDSSYSEPPDVQQQLNHYQSAALARNNNVSPIPLSGSAAGMEKTEAILNCEFCEFSSGYIQSIRRHYRDKHGGKKLFKCKDCSFYTGFKSAFTMHVEAGHSAVPEEGPKDLRCPLCLYHTKYKRNMIDHIVLHREERVVPIEVCRSKLSKYLQGVVFRCDKCTFTCSSDESLQQHIEKHNELKPYKCQLCYYETKHTEELDAHLRDEHKVSRNFELVGRVNLDQLEQMKGKTESSSSDEEEKEEELSPKTEERDSMMFPDSGPPEKRFPCEFCGRSFTEGSEWERHVLRHGMALNESKHGTSEDSQPKEDVEETVSTLPEEKEGIEKMVLDYSHNSETVVSVVTPDKPLQENSEAKNE", "length": 2509, "header": "tr|A0A8V0YNC3-1|A0A8V0YNC3_CHICK Isoform 1 of Zinc finger protein 462 OS=Gallus gallus OX=9031 GN=ZNF462 PE=1 SV=1 CANONICAL=A0A8V0YNC3-1" }, "locus": { "chromosome": "Z", "start_pos": 56238797, "end_pos": 56188794, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034354.1", "url": "https://www.ensembl.org/id/ENSGALT00010034354.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020179.1", "url": "https://www.ensembl.org/id/ENSGALP00010020179.1" } ] } }, { "isoform_ac": "A0A8V0YND1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNC3/entry#A0A8V0YND1-1", "sequence": { "sequence": "MEVLQCDGCDFRAPSYEDLKAHIQDVHTAFLQPTDVSEESPSQPRSGSMNASNQTEVEFSSVKDEFTIADEIAGQNATSQMGTGSYYSQSQTFYGQHMAPNPKPTNKFFQCKFCVRYFRSKNLLIEHTRKVHGAQAGGSSVGPPSASSLNYNIMMHEGFGKVFSCQFCTYKSPRRARIIKHQKMYHKNNLKESSTPPAASTAISESTSASVPVQEPCKELPAEVVERSILESMVKPLTKSRGNFCCEWCSYQTPRRERWCDHMMKKHRSMVKILSSLRQQQEGTSAPDVQNKSAQNASPNSNYISMNTTGREMSNANVSNFRSSMGNSLIRPNSSTSSKFSSVSYPQMKPKSPHNSSIVNLSDRSRYGIADMTNSSADLETNSMLNDSSSDEELNEMDSENGLNSMDHQTTGMSAEQLMGSDGNKLLETKGIPFRRYMNRFQCPFCPFLTMHRRSISRHIENIHLSGKTAVYKCDECPFTCKSSLKLGAHKQCHTGTTSDWDTVNSQAESIASSLNDSTVSYESGNINGRKSAGMMEPVQQQQQQQQQQQSPQPHSQHPYKCTMCNYSTTTLKGLRVHQQHKHSFCDNLPKYDGPPSNTPQESEADAHTSASTVKKSQTSILGLSSKNNFVAKAPRKVSNDFPLDLSPVKKRTRIDEIASNLQSKISQNKQQEDAVINVEDDEEEEEDNEVEIEVELDREEEQTEPMIEVSSSYAPQQMWGREANDSQKETNFRSLQHDYNSANGAEIELTLSEDEEDYYSSVSMKEHQSPNASVLGGQSNMYGTDQNNENAEFSDSGRLYYCKHCDFSNKSARSVSTHYQRMHPYIKFSFRYILDPNDHSAVYRCLECYIDYTNFEDLQQHYGEHHPEAMNVLNFDHSDLIYRCRFCSYTSPNVRSLMPHYQRMHPTVKINNAMIFSSYVVEQQEGLNTESQTLREILNSAPKTMATSTPVARGAGVPAGFNKSAAKSFSPECENQKEPSVNSVVVYDCDVCSFASPNMHSVLVHYQKKHPEEKASYFRIQKTMRVVSVDRGSALAQMSFEMGTPVSPKLSNLASPPPPPPPPDLATELYYCKHCSYSNRSVVGVLVHYQKRHPEIKVTAKYIRQAPPTAAMMRAGELPPGIQRPPVSMQQLSRGGSETSVNPPENEMFFCQHCDYGNRTVKGVLIHYQKKHRDFKANADVIRQHTATIRSLCDRSQKKSSGSVSAHTSSTERDKSKLRALKCRQCSYTSPYFYALRKHIKKDHPNLKATVTSILRWAFLDGLIEAGYHCEWCIYSHTEPSGLLVHYQRRHPEHYVDYTYMATKLWAGPDPSPPALVLPAEAKTYKCRDCIFEASSIWDITNHYQAFHPWAMNGDESVLLDIIKEKDAAEKSGTQPDEAGVRMDSEDQITTSQMDQEPECAEDPSLSQEKTVQLASANPAISSTPYQCTVCQSEYNNLHGLLTHYGKKHPGMKVKAADFAQDIDINPGAVYKCRHCPYINTRIHGVLTHYQKRHPSIKVTAEDFVHDVEQSTDIAQNDVEETSRIFKQGYGAYRCKLCPYTHGTLEKLKIHYEKYHNQPEFDVFAQSPPKVSASLEPDMVTEIKASPEIAAEDVGEISVAAPHFSSSHLVSHTVFRCQLCKYFCSTRKGIARHYRIKHNNVRAQPEGKNNLFKCALCSYTNPIRKGLAAHYQKRHDIDAYYTHCLAASRTVSDKPNKVIIPSPPKDDTPQLSEELRRAVEKKKCSLCSFQSFSKKGIVSHYMKRHPGVFPKKQHASKLGGYFTAVYADEHEKLTPAEERNEFEKPEVESEAQEIEWLPFRCIKCFKLSFSTAELLCMHYTDHHSKDLKRDFTILGSGTRSQNAVYQCKHCDMKLHSTAELTAHLNGHNEEFQKRAKRQERRKQLLSKQKYADGAFADFKQERAFGHLEDVSKLKERKVVGYKCKFCVEVHPTLRAICNHLRKHVQYGNVSSVSATVKQEAEDSSNTTLEGFEGAKDPGILEFAEAESGASLEDETRPGGYHCSQCDRVLMSMQGLRSHERSHLALAMFTREDKYSCQYCSFVSAFRHNLDRHMQTHHGHHKPFRCKLCPFKSSYNSRLKTHILKAHADSSYSEPPDVQQQLNHYQSAALARNNNVSPIPLSGSAAGMEKTEAILNCEFCEFSSGYIQSIRRHYRDKHGGKKLFKCKDCSFYTGFKSAFTMHVEAGHSAVPEEGPKDLRCPLCLYHTKYKRNMIDHIVLHREERVVPIEVCRSKLSKYLQGVVFRCDKCTFTCSSDESLQQHIEKHNELKPYKCQLCYYETKHTEELDAHLRDEHKVSRNFELVGRVNLDQLEQMKGKTESSSSDEEEKEEELSPKTEERDSMMFPDSGPPEKRFPCEFCGRSFTEGSEWERHVLRHGMALNESKHGTSEDSQPKEDVEETVSTLPEEKEGIEKMVLDYSHNSETVVSVVTPDKPLQENSEAKNE", "length": 2445, "header": "tr|A0A8V0YND1-1|A0A8V0YND1_CHICK Computationally mapped isoform of Zinc finger protein 462 OS=Gallus gallus OX=9031 GN=ZNF462 PE=1 SV=1 CANONICAL=A0A8V0YNC3-1" }, "locus": { "chromosome": "Z", "start_pos": 56238797, "end_pos": 56188794, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034361.1", "url": "https://www.ensembl.org/id/ENSGALT00010034361.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020184.1", "url": "https://www.ensembl.org/id/ENSGALP00010020184.1" } ] } }, { "isoform_ac": "A0A8V0YNG7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNC3/entry#A0A8V0YNG7-1", "sequence": { "sequence": "MEVLQCDGCDFRAPSYEDLKAHIQDVHTAFLQPTDVSEESPSQPRSGSMNASNQTEVEFSSVKDEFTIADEIAGQNATSQMGTGSYYSQSQTFYGQHMAPNPKPTNKFFQCKFCVRYFRSKNLLIEHTRKVHGAQAGGSSVGPPSASSLNYNIMMHEGFGKVFSCQFCTYKSPRRARIIKHQKMYHKNNLKESSTPPAASTAISESTSASVPVQEPCKELPAEVVERSILESMVKPLTKSRGNFCCEWCSYQTPRRERWCDHMMKKHRSMVKILSSLRQQQEGTSAPDVQNKSAQNASPNSNYISMNTTGREMSNANVSNFRSSMGNSLIRPNSSTSSKFSSVSYPQMKPKSPHNSSIVNLSDRSRYGIADMTNSSADLETNSMLNDSSSDEELNEMDSENGLNSMDHQTTGMSAEQLMGSDGNKLLETKGIPFRRYMNRFQCPFCPFLTMHRRSISRHIENIHLSGKTAVYKCDECPFTCKSSLKLGAHKQCHTGTTSDWDTVNSQAESIASSLNDSTVSYESGNINGRKSAGMMEPVQQQQQQQQQQQSPQPHSQHPYKCTMCNYSTTTLKGLRVHQQHKHSFCDNLPKYDGPPSNTPQESEADAHTSASTVKKSQTSILGLSSKNNFVAKAPRKVSNDFPLDLSPVKKRTRIDEIASNLQSKISQNKQQEDAVINVEDDEEEEEDNEVEIEVELDREEEQTEPMIEVSSSYAPQQMWGREANDSQKETNFRSLQHDYNSANGAEIELTLSEDEEDYYSSVSMKEHQSPNASVLGGQSNMYGTDQNNENAEFSDSGRLYYCKHCDFSNKSARSVSTHYQRMHPYIKFSFRYILDPNDHSAVYRCLECYIDYTNFEDLQQHYGEHHPEAMNVLNFDHSDLIYRCRFCSYTSPNVRSLMPHYQRMHPTVKINNAMIFSSYVVEQQEGLNTESQTLREILNSAPKTMATSTPVARGAGVPAGFNKSAAKSFSPECENQKEPSVNSVVVYDCDVCSFASPNMHSVLVHYQKKHPEEKASYFRIQKTMRVVSVDRGSALAQMSFEMGTPVSPKLSNLASPPPPPPPPDLATELYYCKHCSYSNRSVVGVLVHYQKRHPEIKVTAKYIRQAPPTAAMMRAGELPPGIQRPPVSMQQLSRGGSETSVNPPENEMFFCQHCDYGNRTVKGVLIHYQKKHRDFKANADVIRQHTATIRSLCDRSQKKSSGSVSAHTSSTERDKSKLRALKCRQCSYTSPYFYALRKHIKKDHPNLKATVTSILRWAFLDGLIEAGYHCEWCIYSHTEPSGLLVHYQRRHPEHYVDYTYMATKLWAGPDPSPPALVLPAEAKTYKCRDCIFEASSIWDITNHYQAFHPWAMNGDESVLLDIIKEKDAAEKSGTQPDEAGVRMDSEDQITTSQMDQEPECAEDPSLSQEKTVQLASANPAISSTPYQCTVCQSEYNNLHGLLTHYGKKHPGMKVKAADFAQDIDINPGAVYKCRHCPYINTRIHGVLTHYQKRHPSIKVTAEDFVHDVEQSTDIAQNDVEETSRIFKQGYGAYRCKLCPYTHGTLEKLKIHYEKYHNQPEFDVFAQSPPKVSASLEPDMVTEIKASPEIAAEDVGEISVAAPHFSSSHLVSHTVFRCQLCKYFCSTRKGIARHYRIKHNNVRAQPEGKNNLFKCALCSYTNPIRKGLAAHYQKRHDIDAYYTHCLAASRTVSDKPNKVIIPSPPKDDTPQLSEELRRAVEKKKCSLCSFQSFSKKGIVSHYMKRHPGVFPKKQHASKLGGYFTAVYADEHEKLTPAEERNEFEKPEVESEAQEIEWLPFRCIKCFKLSFSTAELLCMHYTDHHSKDLKRDFTILGSGTRSQNAVYQCKHCDMKLHSTAELTAHLNGHNEEFQKRAKRQERRKQLLSKQKYADGAFADFKQERAFGHLEDVSKLKERKVVGYKCKFCVEVHPTLRAICNHLRKHVQYGNVSSVSATVKGLRSHERSHLALAMFTREDKYSCQYCSFVSAFRHNLDRHMQTHHGHHKPFRCKLCPFKSSYNSRLKTHILKAHAGEHAYKCSSCSFSTMTISQLKEHSLKVHGKALTLPRPRIVNLAASHAHHTSKNHTPAEEVEDSNACAYCLSSCHWTSLKRAQLQLPCTFPSDSSYSEPPDVQQQLNHYQSAALARNNNVSPIPLSGSAAGMEKTEAILNCEFCEFSSGYIQSIRRHYRDKHGGKKLFKCKDCSFYTGFKSAFTMHVEAGHSAVPEEGPKDLRCPLCLYHTKYKRNMIDHIVLHREERVVPIEVCRSKLSKYLQGVVFRCDKCTFTCSSDESLQQHIEKHNELKPYKCQLCYYETKHTEELDAHLRDEHKVSRNFELVGRVNLDQLEQMKGKTESSSSDEEEKEEELSPKTEERDSMMFPDSGPPEKRFPCEFCGRSFTEGSEWERHVLRHGMALNESKHGTSEDSQPKEDVEETVSTLPEEKEGIEKMVLDYSHNSETVVSVVTPDKPLQENSEAKNE", "length": 2480, "header": "tr|A0A8V0YNG7-1|A0A8V0YNG7_CHICK Computationally mapped isoform of Zinc finger protein 462 OS=Gallus gallus OX=9031 GN=ZNF462 PE=1 SV=1 CANONICAL=A0A8V0YNC3-1" }, "locus": { "chromosome": "Z", "start_pos": 56238797, "end_pos": 56188794, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034357.1", "url": "https://www.ensembl.org/id/ENSGALT00010034357.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020182.1", "url": "https://www.ensembl.org/id/ENSGALP00010020182.1" } ] } }, { "isoform_ac": "A0A8V0YNH2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNC3/entry#A0A8V0YNH2-1", "sequence": { "sequence": "MEVLQCDGCDFRAPSYEDLKAHIQDVHTAFLQPTDVSEESPSQPRSGSMNASNQTEVEFSSVKDEFTIADEIAVQEPCKELPAEVVERSILESMVKPLTKSRGNFCCEWCSYQTPRRERWCDHMMKKHRSMVKILSSLRQQQEGTSAPDVQNKSAQNASPNSNYISMNTTGREMSNANVSNFRSSMGNSLIRPNSSTSSKFSSVSYPQMKPKSPHNSSIVNLSDRSRYGIADMTNSSADLETNSMLNDSSSDEELNEMDSENGLNSMDHQTTGMSAEQLMGSDGNKLLETKGIPFRRYMNRFQCPFCPFLTMHRRSISRHIENIHLSGKTAVYKCDECPFTCKSSLKLGAHKQCHTGTTSDWDTVNSQAESIASSLNDSTVSYESGNINGRKSAGMMEPVQQQQQQQQQQQSPQPHSQHPYKCTMCNYSTTTLKGLRVHQQHKHSFCDNLPKYDGPPSNTPQESEADAHTSASTVKKSQTSILGLSSKNNFVAKAPRKVSNDFPLDLSPVKKRTRIDEIASNLQSKISQNKQQEDAVINVEDDEEEEEDNEVEIEVELDREEEQTEPMIEVSSSYAPQQMWGREANDSQKETNFRSLQHDYNSANGAEIELTLSEDEEDYYSSVSMKEHQSPNASVLGGQSNMYGTDQNNENAEFSDSGRLYYCKHCDFSNKSARSVSTHYQRMHPYIKFSFRYILDPNDHSAVYRCLECYIDYTNFEDLQQHYGEHHPEAMNVLNFDHSDLIYRCRFCSYTSPNVRSLMPHYQRMHPTVKINNAMIFSSYVVEQQEGLNTESQTLREILNSAPKTMATSTPVARGAGVPAGFNKSAAKSFSPECENQKEPSVNSVVVYDCDVCSFASPNMHSVLVHYQKKHPEEKASYFRIQKTMRVVSVDRGSALAQMSFEMGTPVSPKLSNLASPPPPPPPPDLATELYYCKHCSYSNRSVVGVLVHYQKRHPEIKVTAKYIRQAPPTAAMMRAGELPPGIQRPPVSMQQLSRGGSETSVNPPENEMFFCQHCDYGNRTVKGVLIHYQKKHRDFKANADVIRQHTATIRSLCDRSQKKSSGSVSAHTSSTERDKSKLRALKCRQCSYTSPYFYALRKHIKKDHPNLKATVTSILRWAFLDGLIEAGYHCEWCIYSHTEPSGLLVHYQRRHPEHYVDYTYMATKLWAGPDPSPPALVLPAEAKTYKCRDCIFEASSIWDITNHYQAFHPWAMNGDESVLLDIIKEKDAAEKSGTQPDEAGVRMDSEDQITTSQMDQEPECAEDPSLSQEKTVQLASANPAISSTPYQCTVCQSEYNNLHGLLTHYGKKHPGMKVKAADFAQDIDINPGAVYKCRHCPYINTRIHGVLTHYQKRHPSIKVTAEDFVHDVEQSTDIAQNDVEETSRIFKQGYGAYRCKLCPYTHGTLEKLKIHYEKYHNQPEFDVFAQSPPKVSASLEPDMVTEIKASPEIAAEDVGEISVAAPHFSSSHLVSHTVFRCQLCKYFCSTRKGIARHYRIKHNNVRAQPEGKNNLFKCALCSYTNPIRKGLAAHYQKRHDIDAYYTHCLAASRTVSDKPNKVIIPSPPKDDTPQLSEELRRAVEKKKCSLCSFQSFSKKGIVSHYMKRHPGVFPKKQHASKLGGYFTAVYADEHEKLTPAEERNEFEKPEVESEAQEIEWLPFRCIKCFKLSFSTAELLCMHYTDHHSKDLKRDFTILGSGTRSQNAVYQCKHCDMKLHSTAELTAHLNGHNEEFQKRAKRQERRKQLLSKQKYADGAFADFKQERAFGHLEDVSKLKERKVVGYKCKFCVEVHPTLRAICNHLRKHVQYGNVSSVSATVKGLRSHERSHLALAMFTREDKYSCQYCSFVSAFRHNLDRHMQTHHGHHKPFRCKLCPFKSSYNSRLKTHILKAHAGEHAYKCSSCSFSTMTISQLKEHSLKVHGKALTLPRPRIVNLAASHAHHTSKNHTPAEEVEDSNDSSYSEPPDVQQQLNHYQSAALARNNNVSPIPLSGSAAGMEKTEAILNCEFCEFSSGYIQSIRRHYRDKHGGKKLFKCKDCSFYTGFKSAFTMHVEAGHSAVPEEGPKDLRCPLCLYHTKYKRNMIDHIVLHREERVVPIEVCRSKLSKYLQGVVFRCDKCTFTCSSDESLQQHIEKHNELKPYKCQLCYYETKHTEELDAHLRDEHKVSRNFELVGRVNLDQLEQMKGKTESSSSDEEEKEEELSPKTEERDSMMFPDSGPPEKRFPCEFCGRSFTEGSEWERHVLRHGMALNESKHGTSEDSQPKEDVEETVSTLPEEKEGIEKMVLDYSHNSETVVSVVTPDKPLQENSEAKNE", "length": 2314, "header": "tr|A0A8V0YNH2-1|A0A8V0YNH2_CHICK Computationally mapped isoform of Zinc finger protein 462 OS=Gallus gallus OX=9031 GN=ZNF462 PE=1 SV=1 CANONICAL=A0A8V0YNC3-1" }, "locus": { "chromosome": "Z", "start_pos": 56238797, "end_pos": 56188794, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034367.1", "url": "https://www.ensembl.org/id/ENSGALT00010034367.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020187.1", "url": "https://www.ensembl.org/id/ENSGALP00010020187.1" } ] } }, { "isoform_ac": "A0A8V0YQ73-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNC3/entry#A0A8V0YQ73-1", "sequence": { "sequence": "MQTHHGHHKPFRCKLCPFKSSYNSRLKTHILKAHAACAYCLSSCHWTSLKRAQLQLPCTFPSDSSYSEPPDVQQQLNHYQSAALARNNNVSPIPLSGSAAGMEKTEAILNCEFCEFSSGYIQSIRRHYRDKHGGKKLFKCKDCSFYTGFKSAFTMHVEAGHSAVPEEGPKDLRCPLCLYHTKYKRNMIDHIVLHREERVVPIEVCRSKLSKYLQGVVFRCDKCTFTCSSDESLQQHIEKHNELKPYKCQLCYYETKHTEELDAHLRDEHKVSRNFELVGRVNLDQLEQMKGKTESSSSDEEEKEEELSPKTEERDSMMFPDSGPPEKRFPCEFCGRSFTEGSEWERHVLRHGMALNESKHGTSEDSQPKEDVEETVSTLPEEKEGIEKMVLDYSHNSETVVSVVTPDKPLQENSEAKNE", "length": 419, "header": "tr|A0A8V0YQ73-1|A0A8V0YQ73_CHICK Computationally mapped isoform of Zinc finger protein 462 OS=Gallus gallus OX=9031 GN=ZNF462 PE=4 SV=1 CANONICAL=A0A8V0YNC3-1" }, "locus": { "chromosome": "Z", "start_pos": 56238797, "end_pos": 56201303, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034346.1", "url": "https://www.ensembl.org/id/ENSGALT00010034346.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020173.1", "url": "https://www.ensembl.org/id/ENSGALP00010020173.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNC3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNC3" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNC3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNC3" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNC3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNC3" } ], "pmid": "" }, { "name": "transcription cis-regulatory region binding", "id": "GO:0000976", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000976", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNC3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNC3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNC3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNC3" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNC3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNC3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNC3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNC3" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNC3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNC3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1080, "end_pos": 1082, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1159, "end_pos": 1161, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1949, "end_pos": 1951, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1966, "end_pos": 1968, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2141, "end_pos": 2143, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2152, "end_pos": 2154, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2179, "end_pos": 2181, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2446, "end_pos": 2448, "annotation": "n_glycosylation_sequon" }, { "start_pos": 291, "end_pos": 293, "annotation": "n_glycosylation_sequon" }, { "start_pos": 296, "end_pos": 298, "annotation": "n_glycosylation_sequon" }, { "start_pos": 307, "end_pos": 309, "annotation": "n_glycosylation_sequon" }, { "start_pos": 317, "end_pos": 319, "annotation": "n_glycosylation_sequon" }, { "start_pos": 333, "end_pos": 335, "annotation": "n_glycosylation_sequon" }, { "start_pos": 355, "end_pos": 357, "annotation": "n_glycosylation_sequon" }, { "start_pos": 360, "end_pos": 362, "annotation": "n_glycosylation_sequon" }, { "start_pos": 374, "end_pos": 376, "annotation": "n_glycosylation_sequon" }, { "start_pos": 386, "end_pos": 388, "annotation": "n_glycosylation_sequon" }, { "start_pos": 50, "end_pos": 52, "annotation": "n_glycosylation_sequon" }, { "start_pos": 516, "end_pos": 518, "annotation": "n_glycosylation_sequon" }, { "start_pos": 53, "end_pos": 55, "annotation": "n_glycosylation_sequon" }, { "start_pos": 566, "end_pos": 568, "annotation": "n_glycosylation_sequon" }, { "start_pos": 725, "end_pos": 727, "annotation": "n_glycosylation_sequon" }, { "start_pos": 76, "end_pos": 78, "annotation": "n_glycosylation_sequon" }, { "start_pos": 772, "end_pos": 774, "annotation": "n_glycosylation_sequon" }, { "start_pos": 810, "end_pos": 812, "annotation": "n_glycosylation_sequon" }, { "start_pos": 963, "end_pos": 965, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YNC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNC3" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 109, "end_pos": 137, "start_aa": "Phe", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1080, "end_pos": 1082 }, { "start_pos": 1159, "end_pos": 1161 }, { "start_pos": 1949, "end_pos": 1951 }, { "start_pos": 1966, "end_pos": 1968 }, { "start_pos": 2141, "end_pos": 2143 }, { "start_pos": 2152, "end_pos": 2154 }, { "start_pos": 2179, "end_pos": 2181 }, { "start_pos": 2446, "end_pos": 2448 }, { "start_pos": 291, "end_pos": 293 }, { "start_pos": 296, "end_pos": 298 }, { "start_pos": 307, "end_pos": 309 }, { "start_pos": 317, "end_pos": 319 }, { "start_pos": 333, "end_pos": 335 }, { "start_pos": 355, "end_pos": 357 }, { "start_pos": 360, "end_pos": 362 }, { "start_pos": 374, "end_pos": 376 }, { "start_pos": 386, "end_pos": 388 }, { "start_pos": 50, "end_pos": 52 }, { "start_pos": 516, "end_pos": 518 }, { "start_pos": 53, "end_pos": 55 }, { "start_pos": 566, "end_pos": 568 }, { "start_pos": 725, "end_pos": 727 }, { "start_pos": 76, "end_pos": 78 }, { "start_pos": 772, "end_pos": 774 }, { "start_pos": 810, "end_pos": 812 }, { "start_pos": 963, "end_pos": 965 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YNF8-1", "uniprot_ac": "A0A8V0YNF8", "uniprot_id": "A0A8V0YNF8_CHICK", "mass": { "chemical_mass": 95781.0, "monoisotopic_mass": 95781.0 }, "refseq": { "ac": "XP_004940390", "name": "armadillo repeat-containing protein 2 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004940390" }, "gene_names": [ { "name": "ARMC2", "type": "recommended", "evidence": [ { "id": "A0A8V0YNF8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNF8" } ] }, { "name": "ARMC2", "type": "synonym", "evidence": [ { "id": "XP_004940390", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004940390" } ] } ], "protein_names": [ { "name": "Armadillo repeat containing 2", "type": "synonym", "evidence": [ { "id": "A0A8V0YNF8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNF8/entry#names_and_taxonomy" } ] }, { "name": "armadillo repeat-containing protein 2 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_004940390", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004940390" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052534.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_004940390.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004940390", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004940390" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNF8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNF8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ARMC2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNF8", "locus": { "chromosome": "3", "start_pos": 66840880, "end_pos": 66902747, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010014288", "url": "https://www.ensembl.org/id/ENSGALG00010014288" } ] } } ], "crossref": [ { "id": "A0A8V0YNF8", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YNF8", "database": "AlphaFoldDB", "categories": [] }, { "id": "421767", "url": "https://www.ncbi.nlm.nih.gov/gene/421767", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000225", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000225", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038905", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038905", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:421767", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:421767", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "EACIYAY", "url": "https://omabrowser.org/oma/group/EACIYAY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YH49", "url": "https://www.orthodb.org/?gene=A0A8V0YH49", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YNF8", "url": "https://www.orthodb.org/?gene=A0A8V0YNF8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YNJ0", "url": "https://www.orthodb.org/?gene=A0A8V0YNJ0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YVB4", "url": "https://www.orthodb.org/?gene=A0A8V0YVB4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21356", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21356", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21356:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21356:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "XP_004940390", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004940390", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YH49", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH49", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YH49-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH49-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YNF8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNF8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YNF8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNF8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YNJ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNJ0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YNJ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNJ0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YVB4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YVB4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YVB4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YVB4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEKPEPFYRLSVSKQKTSSEIINEARSVLRTLRTQRPFTPAEDQRKLFGSGSSRAPQNRPPSVFSLHASSFDLAESRPASGVRLSPLDYKPILVISSKDEDSSVSLPKPAVDAAEVRKVSDARAQLFRRTSQGDAFPAKMAPLDHHEEKLDCEEPAMMSSLHGTNDNCLAEQRAYTPFNDKSEQLICNEHSGKPEREDVLKGTAGKHLFQLKGESNQMKKHGIVASQPSSIGWKRRLTGLEDDMRTDESEEEKSFWHMKVLPILHELESEDNVESLCLACTKLYQVLNEGNMLGKRFKRRSMLLKTLYKLVEIDSDPLCLKLAKIILSMKVDGKNLLGACKLAFKVCRNGINDYLIQNDTLLDCLLEVLRTEDLQKNNEALLYCLGAIKFMSGNAVLLNEMVNKGAVEMLLQLMKQINSIKENDSHFSSLGHLLVQLTATLRNLADLPQTRCQLVCSGAVSELCVALEQRMNDKDVCTYIVRIFSKLSSYNDFCAALADCSRCYILFLALLNKHQKQQDLVIRIIFILGNLTAKNNQAREQFFKEEGSVNTLMSLFQTYHELDLKEEKWYHERGREEKKNPQHPSKAEDVLIKLIRVLANLSIHPSVGAALAAAHHVVELLVTVLEYKSIEVCEELVINAATTINNLSFYKVKSSAVQDKKLRIAEMLLKLLMSNNMDGVVEAVRVFGNLSQYHEICDFIIQKKIHKFVIALLDAKNQDVCFSACGVLLNLTVDKDRRALLMEEGGIGKLVDCLRDFGPADLQLACLICKTLWNYSENITSAASCFGEDTDTLLMLLTSLLDEELALGYGLDRGDHHKLYWEMEFKPVAEKLLERIQTHRSSVSAAIITAF", "length": 851, "header": "tr|A0A8V0YNF8-1|A0A8V0YNF8_CHICK Isoform 1 of Armadillo repeat containing 2 OS=Gallus gallus OX=9031 GN=ARMC2 PE=4 SV=1 CANONICAL=A0A8V0YNF8-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YH49-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNF8/entry#A0A8V0YH49-1", "sequence": { "sequence": "MEKPEPFYRLSVSKQKTSSEIINEARSVLRTLRTQRPFTPAEDQRKLFGSGSSRAPQNRPPSVFSLHASSFDLAESRPASGVRLSPLDYKPILVISSKDEDSSVSLPKPAVDAAEVRKVSDARAQLFRRTSQGDAFPAKMAPLDHHEEKLDCEEPAMMSSLHGTNDNCLAEQRAYTPFNDKSEQLICNEHSGKPEREDVLKGTAGKHLFQLKGERSELLHGEDRSAL", "length": 227, "header": "tr|A0A8V0YH49-1|A0A8V0YNF8_CHICK Computationally mapped isoform of Armadillo repeat containing 2 OS=Gallus gallus OX=9031 GN=ARMC2 PE=4 SV=1 CANONICAL=A0A8V0YNF8-1" }, "locus": { "chromosome": "3", "start_pos": 66898107, "end_pos": 66892118, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034392.1", "url": "https://www.ensembl.org/id/ENSGALT00010034392.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020195.1", "url": "https://www.ensembl.org/id/ENSGALP00010020195.1" } ] } }, { "isoform_ac": "A0A8V0YNF8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNF8/entry#A0A8V0YNF8-1", "sequence": { "sequence": "MEKPEPFYRLSVSKQKTSSEIINEARSVLRTLRTQRPFTPAEDQRKLFGSGSSRAPQNRPPSVFSLHASSFDLAESRPASGVRLSPLDYKPILVISSKDEDSSVSLPKPAVDAAEVRKVSDARAQLFRRTSQGDAFPAKMAPLDHHEEKLDCEEPAMMSSLHGTNDNCLAEQRAYTPFNDKSEQLICNEHSGKPEREDVLKGTAGKHLFQLKGESNQMKKHGIVASQPSSIGWKRRLTGLEDDMRTDESEEEKSFWHMKVLPILHELESEDNVESLCLACTKLYQVLNEGNMLGKRFKRRSMLLKTLYKLVEIDSDPLCLKLAKIILSMKVDGKNLLGACKLAFKVCRNGINDYLIQNDTLLDCLLEVLRTEDLQKNNEALLYCLGAIKFMSGNAVLLNEMVNKGAVEMLLQLMKQINSIKENDSHFSSLGHLLVQLTATLRNLADLPQTRCQLVCSGAVSELCVALEQRMNDKDVCTYIVRIFSKLSSYNDFCAALADCSRCYILFLALLNKHQKQQDLVIRIIFILGNLTAKNNQAREQFFKEEGSVNTLMSLFQTYHELDLKEEKWYHERGREEKKNPQHPSKAEDVLIKLIRVLANLSIHPSVGAALAAAHHVVELLVTVLEYKSIEVCEELVINAATTINNLSFYKVKSSAVQDKKLRIAEMLLKLLMSNNMDGVVEAVRVFGNLSQYHEICDFIIQKKIHKFVIALLDAKNQDVCFSACGVLLNLTVDKDRRALLMEEGGIGKLVDCLRDFGPADLQLACLICKTLWNYSENITSAASCFGEDTDTLLMLLTSLLDEELALGYGLDRGDHHKLYWEMEFKPVAEKLLERIQTHRSSVSAAIITAF", "length": 851, "header": "tr|A0A8V0YNF8-1|A0A8V0YNF8_CHICK Isoform 1 of Armadillo repeat containing 2 OS=Gallus gallus OX=9031 GN=ARMC2 PE=4 SV=1 CANONICAL=A0A8V0YNF8-1" }, "locus": { "chromosome": "3", "start_pos": 66898107, "end_pos": 66841238, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034410.1", "url": "https://www.ensembl.org/id/ENSGALT00010034410.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020204.1", "url": "https://www.ensembl.org/id/ENSGALP00010020204.1" } ] } }, { "isoform_ac": "A0A8V0YNJ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNF8/entry#A0A8V0YNJ0-1", "sequence": { "sequence": "MEKPEPFYRLSVSKQKTSSEIINEARSVLRTLRTQRPFTPAEDQRKLFGSGSSRAPQNRPPSVFSLHASSFDLAESRPASGVRLSPLDYKPILVISSKDEDSSVSLPKPAVDAAEVRKVSDARAQLFRRTSQGDAFPAKMAPLDHHEEKLDCEEPAMMSSLHGTNDNCLAEQRAYTPFNDKSEQLICNEHSGKPEREDVLKGTAGKHLFQLKGESNQMKKHGIVASQPSSIGWKRRLTGLEDDMRTDESEEEKSFWHMKVLPILHELESEDNVESLCLACTKLYQVLNEGNMLGKRFKRRSMLLKTLYKLVEIDSDPLCLKLAKIILSMKVDGKNLLGACKLAFKVCRNGINDYLIQNDTLLDCLLEVLRTEDLQKNNEALLYCLGAIKFMSGNAVLLNEMVNKGAVEMLLQLMKQINSIKENDSHFSSLGHLLVQLTATLRNLADLPQTRCQLVCSGAVSELCVALEQRMNDKDVCTYIVRIFSKLSSYNDFCAALADCSRCYILFLALLNKHQKQQDLVIRIIFILGNLTAKNNQAREQFFKEEGSVNTLMSLFQTYHELDLKEEKWYHERGREEKKNPQHPSKAEDVLIKLIRVLANLSIHPSVGAALAAAHHVVELLVTVLEYKSIEVCEELVINAATTINNLSFYKVKSSAVQDKKLRIAEIHKFVIALLDAKNQDVCFSACGVLLNLTVDKDRRALLMEEGGIGKLVDCLRDFGPADLQLACLICKTLWNYSENITSAASCFGEDTDTLLMLLTSLLDEELALGYGLDRGDHHKLYWEMEFKPVAEKLLERIQTHRSSVSAAIITAF", "length": 813, "header": "tr|A0A8V0YNJ0-1|A0A8V0YNJ0_CHICK Computationally mapped isoform of Armadillo repeat containing 2 OS=Gallus gallus OX=9031 GN=ARMC2 PE=4 SV=1 CANONICAL=A0A8V0YNF8-1" }, "locus": { "chromosome": "3", "start_pos": 66898107, "end_pos": 66841238, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034405.1", "url": "https://www.ensembl.org/id/ENSGALT00010034405.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020202.1", "url": "https://www.ensembl.org/id/ENSGALP00010020202.1" } ] } }, { "isoform_ac": "A0A8V0YVB4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNF8/entry#A0A8V0YVB4-1", "sequence": { "sequence": "MEKPEPFYRLSVSKQKTSSEIINEARSVLRTLRTQRPFTPAEDQRKLFGSGSSRAPQNRPPSVFSLHASSFDLAESRPASGVRLSPLDYKPILVISSKDEDSSVSLPKPAVDAAEVRKVSDARAQLFRRTSQGDAFPAKMAPLDHHEEKLDCEEPAMMSSLHGTNDNCLAEQRAYTPFNDKSEQLICNEHSGKPEREDVLKGTAGKHLFQLKGEREKNSTEETEWMLLSGRKSVLLCLNFWN", "length": 242, "header": "tr|A0A8V0YVB4-1|A0A8V0YVB4_CHICK Computationally mapped isoform of Armadillo repeat containing 2 OS=Gallus gallus OX=9031 GN=ARMC2 PE=4 SV=1 CANONICAL=A0A8V0YNF8-1" }, "locus": { "chromosome": "3", "start_pos": 66898107, "end_pos": 66888534, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034396.1", "url": "https://www.ensembl.org/id/ENSGALT00010034396.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020196.1", "url": "https://www.ensembl.org/id/ENSGALP00010020196.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:421767", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:421767", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D4AE64-1", "protein_name": "Armadillo repeat containing 2", "gene_name": "Armc2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLRRSALTWTGGEAGFAGSGRAAVRAGGCFYEDHSNLKGKMLSSSEQKLDKLDAFYRLPLAKQKTSAEIISEARNALRTVRTQRPFTPREDQRKLFGPASSRTPENRPPSSFSLHASSFELADPKPISGTRLRPLELKPKAPASPNTEEDANLSFPKAPVDPAKIRRISGARARFYRAASQGTLLPDRSPPAAHSKTPVESRDTVSVGSATAKRNGAHLTASSATRHLKNPPLLPCDQGFRETTEQEASLQPQLGSRGDPGKRRARASSCPSSSDLSRQETRTASRASLQEQEPELEVDETFWKTRIIPILHELEKEEDIEAMCAACTQLHRALEEARMLGKRFKRRSVLLKALYKLVDAGSDALSLKLAKLILALKVSGKNLLNICKLVFKISRSEKNDTLMQKDNILQSLLEVLRDEDLQSNTEAFLYCMGALKFISGSPGFLTEMVNKGTVEILVQLIKETTEDTEKHGACLPNSGHLLVQTTATLRNLVDSPLTRSKLLNIGAFPCLCTVMGQHMNDKDICTNIARVFSKLTSYRDCCAALVSYSRCYALFLSLLNKYQKNQDLVIRIVFILGNLTAKSNQARELFSGESGSVETLLTLFQNFYRLEESSPKLQRSGARPRAEAEDVLVKLTRVLANIAIHPCIGPVLAADPRVVGLLLTTLESKSLGDCEELVINTTAAINNLSFYQVKSSVLQHRKLYVAELLLKLLVSNNMDGILEAVRVFGNLSQDHDVCNFLMQKNVHKFLITLLEAKHQDICFSACGVLLNLTVDKDKRAVLKEGGGIKKLVDCLRDFGPGDWQLACLVCKTLWNFSENITNASECFGDDVTNTLLILLSTFLDEELALDSSFDQDLKSYHRLHWETEFKPVAQELLKRIQSHHTLLEPLPVPSF", "length": 895 }, "evidence": [ { "id": "A0A8V0YNF8", "url": "https://omabrowser.org/oma/group/A0A8V0YNF8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1QBI9-1", "protein_name": "Armadillo repeat-containing protein 2", "gene_name": "armc2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": 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"Zebrafish" }, { "uniprot_canonical_ac": "P0C6R2-1", "protein_name": "Armadillo repeat-containing protein 2", "gene_name": "ARMC2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MLSPNDKKLEKLDPFYLPSLSKQKTSAEIVSEARNALRTVRTQRPFTPREDQRKLFGPASSRTPENRPPSSFSVHASSFEFSDSRPISGTRLSPLEFKPKAPASPDTVEDFCLSFPKPPVDPAKIRRISSARARLFRVASQGALLPARTLLPTQPTRVESEETVTTRDSVVKINGIYLTESKAIGHLKRHPLQLTYDGDFSKITEQEMFKGATSVPFHLRSGGDQGKRRPRASSSSRSPDQSRLDIRAGSKADLQEKNTEIEVDEVFWNTRIVPILHDLEKEENIEMVCATCTQLHHALEEGNMLGNKFKRRSVLLKTLYKLVDVGSDLLSLKLAKIILALKVSGKNLLNVCKLIFKISRSEKNDSLIRNDSILESLLEVLRSEDLQANTEAFLYCMGTIKFISGNPEFLHEMMGKGAVEILMSLIKQVNENTKKSGTCLPNSGHLLVQMTATLRNLVDSPLARSKLLSINALPQLCTVMEQHIGDKDVCTNIARIFSKLTSYHDCCVALASYSRCYALFLNLINKYQKKQDLVVRVVFILGNLTAKNNQAREQFSKEKGSIPTLLSLFHTFYKLDLHSGKRWGEGDERPEARRPAQAEDVLIKLTRVLANLAIHPGVGPAIAAHSHIVGLLLATLESKSIDDCEELVINTTATINNLSYYKVKNSIIQDRKLYIAELLLKLLVSNNMDGILEAVRVFGNLSQDHDICDFIVQKNVHKFMIALLDAKHQDICFSACGVLLNLTVDRDKRLILKEGGGIKKLVDCLRDFGPTDWQLASLVCKTLWNFSENITNAASCFGDEAANTLLALLSSFLDEELALNGSFDQDLKNYHKLHWETEFRPVAQQLLNRIKNHHTFLEPLPIPSF", "length": 865 }, "evidence": [ { "id": "A0A8V0YNF8", "url": "https://omabrowser.org/oma/group/A0A8V0YNF8/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q3URY6-1", "protein_name": "Armadillo repeat-containing protein 2", "gene_name": "Armc2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSSNDQKLEKLDSFYRPPVSKQRTSAEIISEARNALRTVRTQRPFTPREDQRKLFGPASSRSPENRPPSSFSLHASSFELSDSKPISGTRLRPLELKPKAPASPGTEDACLSFPKAPLDPAKIRKISGARARFYRAASQGMLLPDRSPPAAHSKTVDESSKPVSVGSSTARRNGTHLTASSATGQLKSPPLLTCDQGFQETTEQEVSLLSQLRRGGDPGKRRARASSCPSSSDLSRKETRAASRASSQEQETDTEVDEVFWKARIVPILHELENEEDIEEMCAACTQLHRTLEEARMLGKKFKRRTVLLKALYKLVDADSDPLSLKLAKLILALKVSGKNLLNVCKLIFKISRNEKNDTLMQEDNILESLLEVLRAEELQSNTEAFLYCMGALKFVSGSPGFLTEMVNKGAVEILAQLIKEMTEDTEKHGVCLPDSGHLLVQTTATLRNLVDSPLTRSKLLNMGAFPHLCTVMEQHADDKDICTNIARIFSKLTSYRDCCAALASYSRCYALFLSLLNKYQKNQDLVIRIVFILGNLTAKSNQARELFSRETGSVETLLTLFQSFYHHKENSPKLQLSEAKPQAEAEDVLVKLTRVLANIAIHPRIGPVLAANPRVVGLLLRTLESKSLGDCEELVINTIAAINNLSFYQVKSSVLQHRKLYVAELLLRLLVSNNMERILEAVRVFGNLSQDHDVCNFLMQKNVHKFMITLLEAKHQDICFSACGVLLNLTVDKEKRAILKEGGGIKKLVDCLRDFGPSDWQLACLVCKTLWNFSENITNASECFGDDVANTLLILLSTFLDEELALNGSFDQDLESYHRLHWETEFKPVAQQLLQRIQSHHSLLEPLPVPSF", "length": 854 }, "evidence": [ { "id": "A0A8V0YNF8", "url": "https://omabrowser.org/oma/group/A0A8V0YNF8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8IR94-1", "protein_name": "Armadillo repeat-containing protein 2", "gene_name": "Dmel\\CG32668", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": 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"glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q8NEN0-1", "protein_name": "Armadillo repeat-containing protein 2", "gene_name": "ARMC2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": 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], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "cilium organization", "id": "GO:0044782", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044782", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNF8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNF8" } ], "pmid": "" }, { "name": "sperm axoneme assembly", "id": "GO:0007288", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007288", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNF8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNF8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 358, "end_pos": 360, "annotation": "n_glycosylation_sequon" }, { "start_pos": 423, "end_pos": 425, "annotation": "n_glycosylation_sequon" }, { "start_pos": 530, "end_pos": 532, "annotation": "n_glycosylation_sequon" }, { "start_pos": 600, "end_pos": 602, "annotation": "n_glycosylation_sequon" }, { "start_pos": 646, "end_pos": 648, "annotation": "n_glycosylation_sequon" }, { "start_pos": 689, "end_pos": 691, "annotation": "n_glycosylation_sequon" }, { "start_pos": 730, "end_pos": 732, "annotation": "n_glycosylation_sequon" }, { "start_pos": 774, "end_pos": 776, "annotation": "n_glycosylation_sequon" }, { "start_pos": 778, "end_pos": 780, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 358, "end_pos": 360 }, { "start_pos": 423, "end_pos": 425 }, { "start_pos": 530, "end_pos": 532 }, { "start_pos": 600, "end_pos": 602 }, { "start_pos": 646, "end_pos": 648 }, { "start_pos": 689, "end_pos": 691 }, { "start_pos": 730, "end_pos": 732 }, { "start_pos": 774, "end_pos": 776 }, { "start_pos": 778, "end_pos": 780 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", 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0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", 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"type": "synonym", "evidence": [ { "id": "A0A8V0YNK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNK5/entry#names_and_taxonomy" } ] }, { "name": "Ins P4-binding protein", "type": "synonym", "evidence": [ { "id": "A0A8V0YNK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNK5/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNK5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNK5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RASA3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNK5", "locus": { "chromosome": "1", "start_pos": 137147701, "end_pos": 136972899, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010014217", "url": "https://www.ensembl.org/id/ENSGALG00010014217" } ] } } ], "crossref": [ { "id": "A0A8V0YNK5", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YNK5", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd04010", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04010", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd05134", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05134", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd08401", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd08401", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd13371", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13371", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "418736", "url": "https://www.ncbi.nlm.nih.gov/gene/418736", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000008", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000008", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001562", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001562", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001849", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001849", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001936", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001936", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008936", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008936", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023152", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023152", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035892", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035892", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037774", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037774", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039360", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039360", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YH79", "url": "https://www.orthodb.org/?gene=A0A8V0YH79", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YHA5", "url": "https://www.orthodb.org/?gene=A0A8V0YHA5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YNE4", "url": "https://www.orthodb.org/?gene=A0A8V0YNE4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YNF0", "url": "https://www.orthodb.org/?gene=A0A8V0YNF0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YNK5", "url": "https://www.orthodb.org/?gene=A0A8V0YNK5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YNP3", "url": "https://www.orthodb.org/?gene=A0A8V0YNP3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YV99", "url": "https://www.orthodb.org/?gene=A0A8V0YV99", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YVA4", "url": "https://www.orthodb.org/?gene=A0A8V0YVA4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YVA9", "url": "https://www.orthodb.org/?gene=A0A8V0YVA9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YVC4", "url": "https://www.orthodb.org/?gene=A0A8V0YVC4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10194", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10194", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10194:SF53", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10194:SF53", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00168", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00168", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00169", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00169", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00616", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00616", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00779", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00779", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-5658442", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5658442", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YH79", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH79", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YH79-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH79-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHA5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHA5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHA5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHA5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YNE4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNE4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YNE4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNE4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YNF0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNF0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YNF0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNF0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YNK5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNK5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YNK5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNK5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YNP3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNP3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YNP3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNP3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YV99", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YV99", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YV99-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YV99-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YVA4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YVA4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YVA4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YVA4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YVA9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YVA9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YVA9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YVA9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YVC4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YVC4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YVC4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YVC4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGSCLQLTKSKSEMSCIKHSARISEVLTSVLVHVWAASIRQHPCAGILCDVQRSLWNFRAARWDLRCSQRGRAYLKSLLLGQSHWALLDPGEAKNLPTYPGPNKMRDCYCTVNLDQEEVFRTKIVEKSLCPFYGEDFYCEIPRTFRHLSFYIFDRDVFRRDSIIGKVAIQKEDLQKYHNRDTWFQLQHVDADSEVQGKVHLELRLSEVITDTGVVCHKLATRVLECQGLPIVNGQCDPYATVTLAGPSRSEAKKTKVKKKTNNPHFDEVFYFEVTRPSSYNKKSQFDIEDVDEVDKMEIRVDLWNASNLKFGDEFLGELRLPLKFLRQSSSYEAWYFLQPRDNGNKSLKPDDLGSLRLNVVYTEDHVFSSDYYSPLRDLLLKSADVEPVSASAAHILGEVCREKQEAAIPLVRLFLHYGRIVPFISAIASAEVKRTQDPNTIFRGNSLTSKCIDETMKLAGMHYLQVTLKPIIDEICQVHKPCEIDPVKLKDGENLENNRENLRQYVDRIFTVITKSGVSCPTVMCDIFFSLRESAAKRFQGDPDVRYTAVSSFIFLRFFAPAILSPNLFQLTPHHPDPQTSRTLTLISKTIQTLGSLSKSKSANFKESYMATFYDYFNEQKYADAVKNFLDLISSSGRRDHKSIEQPILLKEGFMIKRAQGRKRFGMKNFKKRWFRLTNHEFTYQKSKGDHPLCSIPIENILAVERLEEESFKMKNMFQVIQPERRVLYIQANNCVEAKDWIDILTKVSQCNKKRLTVYHPSAYLNGHWLCCKATADNTPGCTPCTGGLPANIQLDIDGDRETERIYSLFNLYMPKLEKMQEACGSKSVYDGPEEEEYSTFIIDDPKETYKTLKLIIEGVGTLEQEHAQYKRDKFKKTKYGSQEHPIGDKSFQTYIRQQSEISAHSI", "length": 908, "header": "tr|A0A8V0YNK5-1|A0A8V0YNK5_CHICK Isoform 1 of Ras GTPase-activating protein 3 OS=Gallus gallus OX=9031 GN=RASA3 PE=4 SV=1 CANONICAL=A0A8V0YNK5-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YH79-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNK5/entry#A0A8V0YH79-1", "sequence": { "sequence": "MQNRKHLQLINWNFRAARWDLRCSQRGRAYLKSLLLGQSHWALLDPGEAKNLPTYPGPNKMRDCYCTVNLDQEEVFRTKIVEKSLCPFYGEDFYCEIPRTFRHLSFYIFDRDVFRRDSIIGKVAIQKEDLQKYHNRDTWFQLQHVDADSEVQGKVHLELRLSEVITDTGVVCHKLATRVLECQGLPIVNGQCDPYATVTLAGPSRSEAKKTKVKKKTNNPHFDEVFYFEVTRPSSYNKKSQFDIEDVDEVDKMEIRVDLWNASNLKFGDEFLGELRLPLKFLRQSSSYEAWYFLQPRDNGNKSLKPDDLGSLRLNVVYTEDHVFSSDYYSPLRDLLLKSADVEPVSASAAHILGEVCREKQEAAIPLVRLFLHYGRIVPFISAIASAEVKRTQDPNTIFRGNSLTSKCIDETMKLAGMHYLQVTLKPIIDEICQVHKPCEIDPVKLKDGENLENNRENLRQYVDRIFTVITKSGVSCPTVMCDIFFSLRESAAKRFQGDPDVRYTAVSSFIFLRFFAPAILSPNLFQLTPHHPDPQTSRTLTLISKTIQTLGSLSKSKSANFKESYMATFYDYFNEQKYADAVKNFLDLISSSGRRDHKSIEQPILLKEGFMIKRAQGRKRFGMKNFKKRWFRLTNHEFTYQKSKGDHPLCSIPIENILAVERLEEESFKMKNMFQVIQPERRVLYIQANNCVEAKDWIDILTKVSQCNKKRLTVYHPSAYLNGHWLCCKATADNTPGCTPCTGGLPANIQLDIDGDRETERIYSLFNLYMPKLEKMQEACGSKSVYDGPEEEEYSTFIIDDPKETYKTLKLIIEGVGTLEQEHAQYKRDKFKKTKYGSQEHPIGDKSFQTYIRQQSEISAHSI", "length": 864, "header": "tr|A0A8V0YH79-1|A0A8V0YNK5_CHICK Computationally mapped isoform of Ras GTPase-activating protein 3 OS=Gallus gallus OX=9031 GN=RASA3 PE=4 SV=1 CANONICAL=A0A8V0YNK5-1" }, "locus": { "chromosome": "1", "start_pos": 137145911, "end_pos": 136977463, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034435.1", "url": "https://www.ensembl.org/id/ENSGALT00010034435.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020225.1", "url": "https://www.ensembl.org/id/ENSGALP00010020225.1" } ] } }, { "isoform_ac": "A0A8V0YHA5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNK5/entry#A0A8V0YHA5-1", "sequence": { "sequence": "MRDCYCTVNLDQEEVFRTKIVEKSLCPFYGEDFYCEIPRTFRHLSFYIFDRDVFRRDSIIGKVAIQKEDLQKYHNRDTWFQLQHVDADSEVQGKVHLELRLSEVITDTGVVCHKLATRVLECQGLPIVNGQCDPYATVTLAGPSRSEAKKTKVKKKTNNPHFDEVFYFEVTRPSSYNKKSQFDIEDVDEVDKMEIRVDLWNASNLKFGDEFLGELRLPLKFLRQSSSYEAWYFLQPRDNGNKSLKPDDLGSLRLNVVYTEDHVFSSDYYSPLRDLLLKSADVEPVSASAAHILGEVCREKQEAAIPLVRLFLHYGRIVPFISAIASAEVKRTQDPNTIFRGNSLTSKCIDETMKLAGMHYLQVTLKPIIDEICQVHKPCEIDPVKLKDGENLENNRENLRQYVDRIFTVITKSGVSCPTVMCDIFFSLRESAAKRFQGDPDVRYTAVSSFIFLRFFAPAILSPNLFQLTPHHPDPQTSRTLTLISKTIQTLGSLSKSKSANFKESYMATFYDYFNEQKYADAVKNFLDLISSSGRRDHKSIEQPILLKEGFMIKRAQGRKRFGMKNFKKRWFRLTNHEFTYQKSKGDHPLCSIPIENILAVERLEEESFKMKNMFQVIQPERRVLYIQANNCVEAKDWIDILTKVSQCNKKRLTVYHPSAYLNGHWLCCKATADNTPGCTPCTGGLPANIQLDIDGDRETERIYSLFNLYMPKLEKMQEACGSKSVYDGPEEEEYSTFIIDDPKETYKTLKLIIEGVGTLEQEHAQYKRDKFKKTKYGSQEHPIGDKSFQTYIRQQSEISAHSI", "length": 804, "header": "tr|A0A8V0YHA5-1|A0A8V0YNK5_CHICK Computationally mapped isoform of Ras GTPase-activating protein 3 OS=Gallus gallus OX=9031 GN=RASA3 PE=4 SV=1 CANONICAL=A0A8V0YNK5-1" }, "locus": { "chromosome": "1", "start_pos": 137145911, "end_pos": 137052370, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034464.1", "url": "https://www.ensembl.org/id/ENSGALT00010034464.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020245.1", "url": "https://www.ensembl.org/id/ENSGALP00010020245.1" } ] } }, { "isoform_ac": "A0A8V0YNE4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNK5/entry#A0A8V0YNE4-1", "sequence": { "sequence": "MAVEEEGLRVFQSVRIKIGEAKNLPTYPGPNKMRDCYCTVNLDQEEVFRTKIVEKSLCPFYGEDFYCEIPRTFRHLSFYIFDRDVFRRDSIIGKVAIQKEDLQKYHNRDTWFQLQHVDADSEVQGKVHLELRLSEVITDTGVVCHKLATRVLECQGLPIVNGQCDPYATVTLAGPSRSEAKKTKVKKKTNNPHFDEVFYFEVTRPSSYNKKSQFDIEDVDEVDKMEIRVDLWNASNLKFGDEFLGELRLPLKFLRQSSSYEAWYFLQPRDNGNKSLKPDDLGSLRLNVVYTEDHVFSSDYYSPLRDLLLKSADVEPVSASAAHILGEVCREKQEAAIPLVRLFLHYGRIVPFISAIASAEVKRTQDPNTIFRGNSLTSKCIDETMKLAGMHYLQVTLKPIIDEICQVHKPCEIDPVKLKDGENLENNRENLRQYVDRIFTVITKSGVSCPTVMCDIFFSLRESAAKRFQGDPDVRYTAVSSFIFLRFFAPAILSPNLFQLTPHHPDPQTSRTLTLISKTIQTLGSLSKSKSANFKESYMATFYDYFNEQKYADAVKNFLDLISSSGRRDHKSIEQPILLKEGTLKLTVKKVDGNSSCRFMIKRAQGRKRFGMKNFKKRWFRLTNHEFTYQKSKGDHPLCSIPIENILAVERLEEESFKMKNMFQVIQPERRVLYIQANNCVEAKDWIDILTKVSQCNKKRLTVYHPSAYLNGHWLCCKATADNTPGCTPCTGGLPANIQLDIDGDRETERIYSLFNLYMPKLEKMQEACGSKSVYDGPEEEEYSTFIIDDPKETYKTLKLIIEGVGTLEQEHAQYKRDKFKKTKYGSQEHPIGDKSFQTYIRQQSEISAHSI", "length": 852, "header": "tr|A0A8V0YNE4-1|A0A8V0YNE4_CHICK Computationally mapped isoform of RAS p21 protein activator 3 OS=Gallus gallus OX=9031 GN=RASA3 PE=4 SV=1 CANONICAL=A0A8V0YNK5-1" }, "locus": { "chromosome": "1", "start_pos": 137145911, "end_pos": 137016644, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034391.1", "url": "https://www.ensembl.org/id/ENSGALT00010034391.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020194.1", "url": "https://www.ensembl.org/id/ENSGALP00010020194.1" } ] } }, { "isoform_ac": "A0A8V0YNF0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNK5/entry#A0A8V0YNF0-1", "sequence": { "sequence": "MAVEEEGLRVFQSVRIKIGEAKNLPTYPGPNKMRDCYCTVNLDQEEVFRTKIVEKSLCPFYGEDFYCEIPRTFRHLSFYIFDRDVFRRDSIIGKVAIQKEDLQKYHNRDTWFQLQHVDADSEVQGKVHLELRLSEVITDTGVVCHKLATRVLECQGLPIVNGQCDPYATVTLAGPSRSEAKKTKVKKKTNNPHFDEVFYFEVTRPSSYNKKSQFDIEDVDEVDKMEIRVDLWNASNLKFGDEFLGELRLPLKFLRQSSSYEAWYFLQPRDNGNKSLKPDDLGSLRLNVVYTEDHVFSSDYYSPLRDLLLKSADVEPVSASAAHILGEVCREKQEAAIPLVRLFLHYGRIVPFISAIASAEVKRTQDPNTIFRGNSLTSKCIDETMKLAGMHYLQVTLKPIIDEICQVHKPCEIDPVKLKDGENLENNRENLRQYVDRIFTVITKSGVSCPTVMCDIFFSLRESAAKRFQGDPDVRYTAVSSFIFLRFFAPAILSPNLFQLTPHHPDPQTSRTLTLISKTIQTLGSLSKSKSANFKESYMATFYDYFNEQKYADAVKNFLDLISSSGRRDHKSIEQPILLKEGISKWKAIAFMIKRAQGRKRFGMKNFKKRWFRLTNHEFTYQKSKGDHPLCSIPIENILAVERLEEESFKMKNMFQVIQPERRVLYIQANNCVEAKDWIDILTKVSQCNKKRLTVYHPSAYLNGHWLCCKATADNTPGCTPCTGGLPANIQLDIDGDRETERIYSLFNLYMPKLEKMQEACGSKSVYDGPEEEEYSTFIIDDPKETYKTLKLIIEGVGTLEQEHAQYKRDKFKKTKYGSQEHPIGDKSFQTYIRQQSEISAHSI", "length": 844, "header": "tr|A0A8V0YNF0-1|A0A8V0YNF0_CHICK Computationally mapped isoform of Ras GTPase-activating protein 3 OS=Gallus gallus OX=9031 GN=RASA3 PE=4 SV=1 CANONICAL=A0A8V0YNK5-1" }, "locus": { "chromosome": "1", "start_pos": 137145911, "end_pos": 137016644, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034401.1", "url": "https://www.ensembl.org/id/ENSGALT00010034401.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020199.1", "url": "https://www.ensembl.org/id/ENSGALP00010020199.1" } ] } }, { "isoform_ac": "A0A8V0YNK5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNK5/entry#A0A8V0YNK5-1", "sequence": { "sequence": "MGSCLQLTKSKSEMSCIKHSARISEVLTSVLVHVWAASIRQHPCAGILCDVQRSLWNFRAARWDLRCSQRGRAYLKSLLLGQSHWALLDPGEAKNLPTYPGPNKMRDCYCTVNLDQEEVFRTKIVEKSLCPFYGEDFYCEIPRTFRHLSFYIFDRDVFRRDSIIGKVAIQKEDLQKYHNRDTWFQLQHVDADSEVQGKVHLELRLSEVITDTGVVCHKLATRVLECQGLPIVNGQCDPYATVTLAGPSRSEAKKTKVKKKTNNPHFDEVFYFEVTRPSSYNKKSQFDIEDVDEVDKMEIRVDLWNASNLKFGDEFLGELRLPLKFLRQSSSYEAWYFLQPRDNGNKSLKPDDLGSLRLNVVYTEDHVFSSDYYSPLRDLLLKSADVEPVSASAAHILGEVCREKQEAAIPLVRLFLHYGRIVPFISAIASAEVKRTQDPNTIFRGNSLTSKCIDETMKLAGMHYLQVTLKPIIDEICQVHKPCEIDPVKLKDGENLENNRENLRQYVDRIFTVITKSGVSCPTVMCDIFFSLRESAAKRFQGDPDVRYTAVSSFIFLRFFAPAILSPNLFQLTPHHPDPQTSRTLTLISKTIQTLGSLSKSKSANFKESYMATFYDYFNEQKYADAVKNFLDLISSSGRRDHKSIEQPILLKEGFMIKRAQGRKRFGMKNFKKRWFRLTNHEFTYQKSKGDHPLCSIPIENILAVERLEEESFKMKNMFQVIQPERRVLYIQANNCVEAKDWIDILTKVSQCNKKRLTVYHPSAYLNGHWLCCKATADNTPGCTPCTGGLPANIQLDIDGDRETERIYSLFNLYMPKLEKMQEACGSKSVYDGPEEEEYSTFIIDDPKETYKTLKLIIEGVGTLEQEHAQYKRDKFKKTKYGSQEHPIGDKSFQTYIRQQSEISAHSI", "length": 908, "header": "tr|A0A8V0YNK5-1|A0A8V0YNK5_CHICK Isoform 1 of Ras GTPase-activating protein 3 OS=Gallus gallus OX=9031 GN=RASA3 PE=4 SV=1 CANONICAL=A0A8V0YNK5-1" }, "locus": { "chromosome": "1", "start_pos": 137145911, "end_pos": 136986092, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034426.1", "url": "https://www.ensembl.org/id/ENSGALT00010034426.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020217.1", "url": "https://www.ensembl.org/id/ENSGALP00010020217.1" } ] } }, { "isoform_ac": "A0A8V0YNP3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNK5/entry#A0A8V0YNP3-1", "sequence": { "sequence": "MDEHLFGLNHFEKEHHRQPCRSRCGWTFATEAVRAGEAKNLPTYPGPNKMRDCYCTVNLDQEEVFRTKIVEKSLCPFYGEDFYCEIPRTFRHLSFYIFDRDVFRRDSIIGKVAIQKEDLQKYHNRDTWFQLQHVDADSEVQGKVHLELRLSEVITDTGVVCHKLATRVLECQGLPIVNGQCDPYATVTLAGPSRSEAKKTKVKKKTNNPHFDEVFYFEVTRPSSYNKKSQFDIEDVDEVDKMEIRVDLWNASNLKFGDEFLGELRLPLKFLRQSSSYEAWYFLQPRDNGNKSLKPDDLGSLRLNVVYTEDHVFSSDYYSPLRDLLLKSADVEPVSASAAHILGEVCREKQEAAIPLVRLFLHYGRIVPFISAIASAEVKRTQDPNTIFRGNSLTSKCIDETMKLAGMHYLQVTLKPIIDEICQVHKPCEIDPVKLKDGENLENNRENLRQYVDRIFTVITKSGVSCPTVMCDIFFSLRESAAKRFQGDPDVRYTAVSSFIFLRFFAPAILSPNLFQLTPHHPDPQTSRTLTLISKTIQTLGSLSKSKSANFKESYMATFYDYFNEQKYADAVKNFLDLISSSGRRDHKSIEQPILLKEGFMIKRAQGRKRFGMKNFKKRWFRLTNHEFTYQKSKGDHPLCSIPIENILAVERLEEESFKMKNMFQVIQPERRVLYIQANNCVEAKDWIDILTKVSQCNKKRLTVYHPSAYLNGHWLCCKATADNTPGCTPCTGGLPANIQLDIDGDRETERIYSLFNLYMPKLEKMQEACGSKSVYDGPEEEEYSTFIIDDPKETYKTLKLIIEGVGTLEQEHAQYKRDKFKKTKYGSQEHPIGDKSFQTYIRQQSEISAHSI", "length": 853, "header": "tr|A0A8V0YNP3-1|A0A8V0YNP3_CHICK Computationally mapped isoform of Ras GTPase-activating protein 3 OS=Gallus gallus OX=9031 GN=RASA3 PE=4 SV=1 CANONICAL=A0A8V0YNK5-1" }, "locus": { "chromosome": "1", "start_pos": 137145911, "end_pos": 137038463, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034481.1", "url": "https://www.ensembl.org/id/ENSGALT00010034481.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020257.1", "url": "https://www.ensembl.org/id/ENSGALP00010020257.1" } ] } }, { "isoform_ac": "A0A8V0YV99-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNK5/entry#A0A8V0YV99-1", "sequence": { "sequence": "MHEMRYFVLFLHQLKVLVGLVFLCCSSSVVTHTASDLPLNNSAEGKNYAYTEGEAKNLPTYPGPNKMRDCYCTVNLDQEEVFRTKIVEKSLCPFYGEDFYCEIPRTFRHLSFYIFDRDVFRRDSIIGKVAIQKEDLQKYHNRDTWFQLQHVDADSEVQGKVHLELRLSEVITDTGVVCHKLATRVLECQGLPIVNGQCDPYATVTLAGPSRSEAKKTKVKKKTNNPHFDEVFYFEVTRPSSYNKKSQFDIEDVDEVDKMEIRVDLWNASNLKFGDEFLGELRLPLKFLRQSSSYEAWYFLQPRDNGNKSLKPDDLGSLRLNVVYTEDHVFSSDYYSPLRDLLLKSADVEPVSASAAHILGEVCREKQEAAIPLVRLFLHYGRIVPFISAIASAEVKRTQDPNTIFRGNSLTSKCIDETMKLAGMHYLQVTLKPIIDEICQVHKPCEIDPVKLKDGENLENNRENLRQYVDRIFTVITKSGVSCPTVMCDIFFSLRESAAKRFQGDPDVRYTAVSSFIFLRFFAPAILSPNLFQLTPHHPDPQTSRTLTLISKTIQTLGSLSKSKSANFKESYMATFYDYFNEQKYADAVKNFLDLISSSGRRDHKSIEQPILLKEGFMIKRAQGRKRFGMKNFKKRWFRLTNHEFTYQKSKGDHPLCSIPIENILAVERLEEESFKMKNMFQVIQPERRVLYIQANNCVEAKDWIDILTKVSQCNKKRLTVYHPSAYLNGHWLCCKATADNTPGCTPCTGGLPANIQLDIDGDRETERIYSLFNLYMPKLEKMQEACGSKSVYDGPEEEEYSTFIIDDPKETYKTLKLIIEGVGTLEQEHAQYKRDKFKKTKYGSQEHPIGDKSFQTYIRQQSEISAHSI", "length": 870, "header": "tr|A0A8V0YV99-1|A0A8V0YV99_CHICK Computationally mapped isoform of Ras GTPase-activating protein 3 OS=Gallus gallus OX=9031 GN=RASA3 PE=4 SV=1 CANONICAL=A0A8V0YNK5-1" }, "locus": { "chromosome": "1", "start_pos": 137145911, "end_pos": 137051044, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034356.1", "url": "https://www.ensembl.org/id/ENSGALT00010034356.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020181.1", "url": "https://www.ensembl.org/id/ENSGALP00010020181.1" } ] } }, { "isoform_ac": "A0A8V0YVA4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNK5/entry#A0A8V0YVA4-1", "sequence": { "sequence": "MAWVGRDLKDHRAPTPRWLLLCLLSPASCEAKNLPTYPGPNKMRDCYCTVNLDQEEVFRTKIVEKSLCPFYGEDFYCEIPRTFRHLSFYIFDRDVFRRDSIIGKVAIQKEDLQKYHNRDTWFQLQHVDADSEVQGKVHLELRLSEVITDTGVVCHKLATRVLECQGLPIVNGQCDPYATVTLAGPSRSEAKKTKVKKKTNNPHFDEVFYFEVTRPSSYNKKSQFDIEDVDEVDKMEIRVDLWNASNLKFGDEFLGELRLPLKFLRQSSSYEAWYFLQPRDNGNKSLKPDDLGSLRLNVVYTEDHVFSSDYYSPLRDLLLKSADVEPVSASAAHILGEVCREKQEAAIPLVRLFLHYGRIVPFISAIASAEVKRTQDPNTIFRGNSLTSKCIDETMKLAGMHYLQVTLKPIIDEICQVHKPCEIDPVKLKDGENLENNRENLRQYVDRIFTVITKSGVSCPTVMCDIFFSLRESAAKRFQGDPDVRYTAVSSFIFLRFFAPAILSPNLFQLTPHHPDPQTSRTLTLISKTIQTLGSLSKSKSANFKESYMATFYDYFNEQKYADAVKNFLDLISSSGRRDHKSIEQPILLKEGFMIKRAQGRKRFGMKNFKKRWFRLTNHEFTYQKSKGDHPLCSIPIENILAVERLEEESFKMKNMFQVIQPERRVLYIQANNCVEAKDWIDILTKVSQCNKKRLTVYHPSAYLNGHWLCCKATADNTPGCTPCTGGLPANIQLDIDGDRETERIYSLFNLYMPKLEKMQEACGSKSVYDGPEEEEYSTFIIDDPKETYKTLKLIIEGVGTLEQEHAQYKRDKFKKTKYGSQEHPIGDKSFQTYIRQQSEISAHSI", "length": 846, "header": "tr|A0A8V0YVA4-1|A0A8V0YVA4_CHICK Computationally mapped isoform of Ras GTPase-activating protein 3 OS=Gallus gallus OX=9031 GN=RASA3 PE=4 SV=1 CANONICAL=A0A8V0YNK5-1" }, "locus": { "chromosome": "1", "start_pos": 137145911, "end_pos": 137024837, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034363.1", "url": "https://www.ensembl.org/id/ENSGALT00010034363.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020186.1", "url": "https://www.ensembl.org/id/ENSGALP00010020186.1" } ] } }, { "isoform_ac": "A0A8V0YVA9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNK5/entry#A0A8V0YVA9-1", "sequence": { "sequence": "MAVEEEGLRVFQSVRIKIGEAKNLPTYPGPNKMRDCYCTVNLDQEEVFRTKIVEKSLCPFYGEDFYCEIPRTFRHLSFYIFDRDVFRRDSIIGKVAIQKEDLQKYHNRDTWFQLQHVDADSEVQGKVHLELRLSEVITDTGVVCHKLATRVLECQGLPIVNGQCDPYATVTLAGPSRSEAKKTKVKKKTNNPHFDEVFYFEVTRPSSYNKKSQFDIEDVDEVDKMEIRVDLWNASNLKFGDEFLGELRLPLKFLRQSSSYEAWYFLQPRDNGNKSLKPDDLGSLRLNVVYTEDHVFSSDYYSPLRDLLLKSADVEPVSASAAHILGEVCREKQEAAIPLVRLFLHYGRIVPFISAIASAEVKRTQDPNTIFRGNSLTSKCIDETMKLAGMHYLQVTLKPIIDEICQVHKPCEIDPVKLKDGENLENNRENLRQYVDRIFTVITKSGVSCPTVMCDIFFSLRESAAKRFQGDPDVRYTAVSSFIFLRFFAPAILSPNLFQLTPHHPDPQTSRTLTLISKTIQTLGSLSKSKSANFKESYMATFYDYFNEQKYADAVKNFLDLISSSGRRDHKSIEQPILLKEGTLKLTVKKVDGNSSCRISKWKAIAFMIKRAQGRKRFGMKNFKKRWFRLTNHEFTYQKSKGDHPLCSIPIENILAVERLEEESFKMKNMFQVIQPERRVLYIQANNCVEAKDWIDILTKVSQCNKKRLTVYHPSAYLNGHWLCCKATADNTPGCTPCTGGLPANIQLDIDGDRETERIYSLFNLYMPKLEKMQEACGSKSVYDGPEEEEYSTFIIDDPKETYKTLKLIIEGVGTLEQEHAQYKRDKFKKTKYGSQEHPIGDKSFQTYIRQQSEISAHSI", "length": 860, "header": "tr|A0A8V0YVA9-1|A0A8V0YVA9_CHICK Computationally mapped isoform of RAS p21 protein activator 3 OS=Gallus gallus OX=9031 GN=RASA3 PE=4 SV=1 CANONICAL=A0A8V0YNK5-1" }, "locus": { "chromosome": "1", "start_pos": 137145911, "end_pos": 137016644, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034380.1", "url": "https://www.ensembl.org/id/ENSGALT00010034380.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020191.1", "url": "https://www.ensembl.org/id/ENSGALP00010020191.1" } ] } }, { "isoform_ac": "A0A8V0YVC4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNK5/entry#A0A8V0YVC4-1", "sequence": { "sequence": "MVAMGSRVGGFRESSLAGLLQGLQQCHDFCHEMHVINKWNFRAARWDLRCSQRGRAYLKSLLLGQSHWALLDPGEAKNLPTYPGPNKMRDCYCTVNLDQEEVFRTKIVEKSLCPFYGEDFYCEIPRTFRHLSFYIFDRDVFRRDSIIGKVAIQKEDLQKYHNRDTWFQLQHVDADSEVQGKVHLELRLSEVITDTGVVCHKLATRVLECQGLPIVNGQCDPYATVTLAGPSRSEAKKTKVKKKTNNPHFDEVFYFEVTRPSSYNKKSQFDIEDVDEVDKMEIRVDLWNASNLKFGDEFLGELRLPLKFLRQSSSYEAWYFLQPRDNGNKSLKPDDLGSLRLNVVYTEDHVFSSDYYSPLRDLLLKSADVEPVSASAAHILGEVCREKQEAAIPLVRLFLHYGRIVPFISAIASAEVKRTQDPNTIFRGNSLTSKCIDETMKLAGMHYLQVTLKPIIDEICQVHKPCEIDPVKLKDGENLENNRENLRQYVDRIFTVITKSGVSCPTVMCDIFFSLRESAAKRFQGDPDVRYTAVSSFIFLRFFAPAILSPNLFQLTPHHPDPQTSRTLTLISKTIQTLGSLSKSKSANFKESYMATFYDYFNEQKYADAVKNFLDLISSSGRRDHKSIEQPILLKEGFMIKRAQGRKRFGMKNFKKRWFRLTNHEFTYQKSKGDHPLCSIPIENILAVERLEEESFKMKNMFQVIQPERRVLYIQANNCVEAKDWIDILTKVSQCNKKRLTVYHPSAYLNGHWLCCKATADNTPGCTPCTGGLPANIQLDIDGDRETERIYSLFNLYMPKLEKMQEACGSKSVYDGPEEEEYSTFIIDDPKETYKTLKLIIEGVGTLEQEHAQYKRDKFKKTKYGSQEHPIGDKSFQTYIRQQSEISAHSI", "length": 891, "header": "tr|A0A8V0YVC4-1|A0A8V0YVC4_CHICK Computationally mapped isoform of Ras GTPase-activating protein 3 OS=Gallus gallus OX=9031 GN=RASA3 PE=4 SV=1 CANONICAL=A0A8V0YNK5-1" }, "locus": { "chromosome": "1", "start_pos": 137145911, "end_pos": 137002375, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034411.1", "url": "https://www.ensembl.org/id/ENSGALT00010034411.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020206.1", "url": "https://www.ensembl.org/id/ENSGALP00010020206.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-5658442", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5658442", "resource": "Reactome", "description": "Regulation of RAS by GAPs" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "negative regulation of Ras protein signal transduction", "id": "GO:0046580", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046580", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNK5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNK5" } ], "pmid": "" }, { "name": "intracellular signal transduction", "id": "GO:0035556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035556", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNK5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNK5" } ], "pmid": "" }, { "name": "response to stress", "id": "GO:0006950", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006950", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNK5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNK5" } ], "pmid": "" }, { "name": "platelet activation", "id": "GO:0030168", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030168", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNK5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNK5" } ], "pmid": "" }, { "name": "regulation of intracellular signal transduction", "id": "GO:1902531", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902531", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNK5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNK5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNK5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNK5" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNK5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNK5" } ], "pmid": "" }, { "name": "calcium channel regulator activity", "id": "GO:0005246", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005246", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNK5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNK5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasmic side of plasma membrane", "id": "GO:0009898", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009898", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNK5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNK5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 305, "end_pos": 307, "annotation": "n_glycosylation_sequon" }, { "start_pos": 345, "end_pos": 347, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YNK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNK5" }, { "id": "PS50004", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50004" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2", "eco_id": "ECO_0000259", "start_pos": 64, "end_pos": 184, "start_aa": "Asp", "end_aa": "Phe", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0YNK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNK5" }, { "id": "PS50003", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50003" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PH", "eco_id": "ECO_0000259", "start_pos": 649, "end_pos": 751, "start_aa": "Ile", "end_aa": "Gln", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0YNK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNK5" }, { "id": "PS50018", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50018" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ras-GAP", "eco_id": "ECO_0000259", "start_pos": 403, "end_pos": 597, "start_aa": "Glu", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 305, "end_pos": 307 }, { "start_pos": 345, "end_pos": 347 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YQ55-1", "uniprot_ac": "A0A8V0YQ55", "uniprot_id": "A0A8V0YQ55_CHICK", "mass": { "chemical_mass": 105504.0, "monoisotopic_mass": 105504.0 }, "refseq": {}, "gene_names": [ { "name": "MORC4", "type": "recommended", "evidence": [ { "id": "A0A8V0YQ55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ55" } ] } ], "protein_names": [ { "name": "MORC family CW-type zinc finger 4", "type": "synonym", "evidence": [ { "id": "A0A8V0YQ55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ55/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQ55", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ55" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MORC4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ55", "locus": { "chromosome": "1", "start_pos": 106754133, "end_pos": 106726276, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013037", "url": "https://www.ensembl.org/id/ENSGALG00010013037" } ] } } ], "crossref": [ { "id": "A0A8V0YQ55", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YQ55", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000036556", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000036556", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd16931", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16931", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "418513", "url": "https://www.ncbi.nlm.nih.gov/gene/418513", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011124", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011124", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036890", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036890", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041006", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041006", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045261", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045261", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:418513", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418513", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "IPYEKTH", "url": "https://omabrowser.org/oma/group/IPYEKTH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5NTQ9", "url": "https://www.orthodb.org/?gene=A0A1D5NTQ9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YH89", "url": "https://www.orthodb.org/?gene=A0A8V0YH89", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YQ51", "url": "https://www.orthodb.org/?gene=A0A8V0YQ51", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YQ55", "url": "https://www.orthodb.org/?gene=A0A8V0YQ55", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23336", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23336", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23336:SF17", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23336:SF17", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07496", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07496", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13589", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13589", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17942", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17942", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A1D5NTQ9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NTQ9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5NTQ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NTQ9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YH89", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH89", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YH89-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH89-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQ51", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ51", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQ51-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ51-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQ55", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ55", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQ55-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ55-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAKTQGGIRLSALCPKFLHTNSTSHTWPFSAVAELIDNAYDPDVSAKQIWIDKTVINNNICLTFTDNGNGMNSEKLHKMLSFGFSEKSVMNGRVPVGLYGNGFKSGSMRLGKDAIVFTKNGETMSVGLLSQTYLEVTKAEHVMVPIVTFNNQRQISDPAESKNSLKAILTHSLFSTEEKLLAELDAIMGKKGTRIIIWNLRRDKNDKTEFDFDKDKYDIRIPEDLDETGKRGYKKQERLDQIVPESDYSLRAYCSILYLKPRMQIILRGQKVKTQLVSKSLAFIERDIYRPKFLNAKTVRITFGFNCRNKDHYGIMMYHKNRLIKAYERVGCQLKANNMGVGVVGIIECNFLKPTHNKQDFDYTNEYRLTIAALGEKLNDYWNEMKAKKNEEYPLALPVEEIQKQPDQTWVQCDACLKWRKLPDGIEHLPEKWYCSLNPDPQFRDCNVPEEPEDDDLIHPTYEKTYKKKDREKLKKRLEYQISNEMLLKTTVSSSKDFRTFSPVSGREAVPRVLLPETSNASVKRPLLVSNRSVSSPHSDSDNSLKRKILISVTPVTIKTPRLNDRAFNRRDDDDDVIILEESSTPKPSADSEVPVVKTECINVDQEEQKKNSDVREPCSASTSESKSEQLTSATQTEVPNLVVKKEEVEDNIDIQVPSTEMETNRHNVNNLSDTSADLGNELRNQLQLVNKEKEMYQSKCEALTKQVETLEQRILEMNDKYVKKEMCHQSTETVSSFAEENVHERSLAETTHLYEQALEEIAKLKEQCSTLQNLKTECSRCADGESKSEVDEIAVQLDDVFRQLDKCTIERDEYKSQVELLEVEKNKIACQCEELKSEIAELKASIPQAVARANDSTASNVEDTVNFSDGERAGRKEDLNYRLANTTSVPGKTLKQICLEAACKLMIVNMNEGIEKIKPDSSPAQ", "length": 927, "header": "tr|A0A8V0YQ55-1|A0A8V0YQ55_CHICK Isoform 1 of MORC family CW-type zinc finger 4 OS=Gallus gallus OX=9031 GN=MORC4 PE=1 SV=1 CANONICAL=A0A8V0YQ55-1" }, "isoforms": [ { "isoform_ac": "A0A1D5NTQ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ55/entry#A0A1D5NTQ9-1", "sequence": { "sequence": "MAAKTQGGIRLSALCPKFLHTNSTSHTWPFSAVAELIDNAYDPDVSAKQIWIDKTVINNNICLTFTDNGNGMNSEKLHKMLSFGFSEKSVMNGRVPVGLYGNGFKSGSMRLGKDAIVFTKNGETMSVGLLSQTYLEVTKAEHVMVPIVTFNNQRQISDPAESKNSLKAILTHSLFSTEEKLLAELDAIMGKKGTRIIIWNLRRDKNDKTEFDFDKDKYDIRIPEDLDETGKRGYKKQERLDQIVPESDYSLRAYCSILYLKPRMQIILRGQKVKTQLVSKSLAFIERDIYRPKFLNAKTVRITFGFNCRNKDHYGIMMYHKNRLIKAYERVGCQLKANNMGVGVVGIIECNFLKPTHNKQDFDYTNEYRLTIAALGEKLNDYWNEMKAKKNEEYPLALPVEEIQKQPDQTWVQCDACLKWRKLPDGIEHLPEKWYCSLNPDPQFRDCNVPEEPEDDDLIHPTYEKTYKKKDREKLKKRLEYQISNEMLLKTTVSSSKDFRTFSPVSGREAVPRVLLPETSNASVKRPLLVSNRSVSSPHSDSDNSLKRKILISVTPVTIKTPRLNDRAFNRRDDDDDVIILEESSTPKPSADSEVPVVKTECINVDQEEQKKNSDVREPCSASTSESKSEQLTSATQTEVPNLVVKKEEVEDNIDIQVPSTEMETNRHNVNNLSDTSADLGNELRNQLQLVNKEKEMYQSKCEALTKQVETLEQRILEMNDKYVKKEMCHQSTETVSSFAEENVHERSLAETTHLYEQALEEIAKLKEQCSTLQNLKTECSRCADGESKSEVDEIAVQLDDVFRQLDKCTIERDEYKSQVELLEVEKNKIACQCEELKSEIAELKASIPQAVARANDSTASNVEDTVNFSDGESLKLRSLRVNVGQLLATIMPDLDLQQVNYDIDVVDEILGQVVEQMHEISST", "length": 924, "header": "tr|A0A1D5NTQ9-1|A0A1D5NTQ9_CHICK Computationally mapped isoform of MORC family CW-type zinc finger 4 OS=Gallus gallus OX=9031 GN=MORC4 PE=1 SV=2 CANONICAL=A0A8V0YQ55-1" }, "locus": { "chromosome": "1", "start_pos": 106751963, "end_pos": 106726393, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031345.1", "url": "https://www.ensembl.org/id/ENSGALT00010031345.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018280.1", "url": "https://www.ensembl.org/id/ENSGALP00010018280.1" } ] } }, { "isoform_ac": "A0A8V0YH89-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ55/entry#A0A8V0YH89-1", "sequence": { "sequence": "MMHQLCPKFLHTNSTSHTWPFSAVAELIDNAYDPDVSAKQIWIDKTVINNNICLTFTDNGNGMNSEKLHKMLSFGFSEKSVMNGRVPVGLYGNGFKSGSMRLGKDAIVFTKNGETMSVGLLSQTYLEVTKAEHVMVPIVTFNNQRQISDPAESKNSLKAILTHSLFSTEEKLLAELDAIMGKKGTRIIIWNLRRDKNDKTEFDFDKDKYDIRIPEDLDETGKRGYKKQERLDQIVPESDYSLRAYCSILYLKPRMQIILRGQKVKTQLVSKSLAFIERDIYRPKFLNAKTVRITFGFNCRNKDHYGIMMYHKNRLIKAYERVGCQLKANNMGVGVVGIIECNFLKPTHNKQDFDYTNEYRLTIAALGEKLNDYWNEMKAKKNEEYPLALPVEEIQKQPDQTWVQCDACLKWRKLPDGIEHLPEKWYCSLNPDPQFRDCNVPEEPEDDDLIHPTYEKTYKKKDREKLKKRLEYQISNEMLLKTTVSSSKDFRTFSPVSGREAVPRVLLPETSNASVKRPLLVSNRSVSSPHSDSDNSLKRKILISVTPVTIKTPRLNDRAFNRRDDDDDVIILEESSTPKPSADSEVPVVKTECINVDQEEQKKNSDVREPCSASTSESKSEQLTSATQTEVPNLVVKKEEVEDNIDIQVPSTEMETNRHNVNNLSDTSADLGNELRNQLQLVNKEKEMYQSKCEALTKQVETLEQRILEMNDKYVKKEMCHQSTETVSSFAEENVHERSLAETTHLYEQALEEIAKLKEQCSTLQNLKTECSRCADGESKSEVDEIAVQLDDVFRQLDKCTIERDEYKSQVELLEVEKNKIACQCEELKSEIAELKASIPQAVARANDSTASNVEDTVNFSDGERYQFFSF", "length": 871, "header": "tr|A0A8V0YH89-1|A0A8V0YQ55_CHICK Computationally mapped isoform of MORC family CW-type zinc finger 4 OS=Gallus gallus OX=9031 GN=MORC4 PE=1 SV=1 CANONICAL=A0A8V0YQ55-1" }, "locus": { "chromosome": "1", "start_pos": 106748960, "end_pos": 106727147, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031273.1", "url": "https://www.ensembl.org/id/ENSGALT00010031273.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018228.1", "url": "https://www.ensembl.org/id/ENSGALP00010018228.1" } ] } }, { "isoform_ac": "A0A8V0YQ51-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ55/entry#A0A8V0YQ51-1", "sequence": { "sequence": "MISETQSGCFLCHTWPFSAVAELIDNAYDPDVSAKQIWIDKTVINNNICLTFTDNGNGMNSEKLHKMLSFGFSEKSVMNGRVPVGLYGNGFKSGSMRLGKDAIVFTKNGETMSVGLLSQTYLEVTKAEHVMVPILLSLTFCLRQISDPAESKNSLKAILTHSLFSTEEKLLAELDAIMGKKGTRIIIWNLRRDKNDKTEFDFDKDKYDIRIPEDLDETGKRGYKKQERLDQIVPESDYSLRAYCSILYLKPRMQIILRGQKVKTQLVSKSLAFIERDIYRPKFLNAKTVRITFGFNCRNKDHYGIMMYHKNRLIKAYERVGCQLKANNMGVGVVGIIECNFLKPTHNKQDFDYTNEYRLTIAALGEKLNDYWNEMKAKKNEEYPLALPVEEIQKQPDQTWVQCDACLKWRKLPDGIEHLPEKWYCSLNPDPQFRDCNVPEEPEDDDLIHPTYEKTYKKKDREKLKKRLEYQISNEMLLKTTVSSSKDFRTFSPVSGREAVPRVLLPETSNASVKRPLLVSNRSVSSPHSDSDNSLKRKILISVTPVTIKTPRLNDRAFNRRDDDDDVIILEESSTPKPSADSEVPVVKTECINVDQEEQKKNSDVREPCSASTSESKSEQLTSATQTEVPNLVVKKEEVEDNIDIQVPSTEMETNRHNVNNLSDTSADLGNELRNQLQLVNKEKEMYQSKCEALTKQVETLEQRILEMNDKYVKKEMCHQSTETVSSFAEENVHERSLAETTHLYEQALEEIAKLKEQCSTLQNLKTECSRCADGESKSEVDEIAVQLDDVFRQLDKCTIERDEYKSQVELLEVEKNKIACQCEELKSEIAELKASIPQAVARANDSTASNVEDTVNFSDGESLKLRSLRVNVGQLLATIMPDLDLQQVNYDIDVVDEILGQVVEQMHEISST", "length": 913, "header": "tr|A0A8V0YQ51-1|A0A8V0YQ51_CHICK Computationally mapped isoform of MORC family CW-type zinc finger 4 OS=Gallus gallus OX=9031 GN=MORC4 PE=1 SV=1 CANONICAL=A0A8V0YQ55-1" }, "locus": { "chromosome": "1", "start_pos": 106751963, "end_pos": 106730257, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031332.1", "url": "https://www.ensembl.org/id/ENSGALT00010031332.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018271.1", "url": "https://www.ensembl.org/id/ENSGALP00010018271.1" } ] } }, { "isoform_ac": "A0A8V0YQ55-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ55/entry#A0A8V0YQ55-1", "sequence": { "sequence": "MAAKTQGGIRLSALCPKFLHTNSTSHTWPFSAVAELIDNAYDPDVSAKQIWIDKTVINNNICLTFTDNGNGMNSEKLHKMLSFGFSEKSVMNGRVPVGLYGNGFKSGSMRLGKDAIVFTKNGETMSVGLLSQTYLEVTKAEHVMVPIVTFNNQRQISDPAESKNSLKAILTHSLFSTEEKLLAELDAIMGKKGTRIIIWNLRRDKNDKTEFDFDKDKYDIRIPEDLDETGKRGYKKQERLDQIVPESDYSLRAYCSILYLKPRMQIILRGQKVKTQLVSKSLAFIERDIYRPKFLNAKTVRITFGFNCRNKDHYGIMMYHKNRLIKAYERVGCQLKANNMGVGVVGIIECNFLKPTHNKQDFDYTNEYRLTIAALGEKLNDYWNEMKAKKNEEYPLALPVEEIQKQPDQTWVQCDACLKWRKLPDGIEHLPEKWYCSLNPDPQFRDCNVPEEPEDDDLIHPTYEKTYKKKDREKLKKRLEYQISNEMLLKTTVSSSKDFRTFSPVSGREAVPRVLLPETSNASVKRPLLVSNRSVSSPHSDSDNSLKRKILISVTPVTIKTPRLNDRAFNRRDDDDDVIILEESSTPKPSADSEVPVVKTECINVDQEEQKKNSDVREPCSASTSESKSEQLTSATQTEVPNLVVKKEEVEDNIDIQVPSTEMETNRHNVNNLSDTSADLGNELRNQLQLVNKEKEMYQSKCEALTKQVETLEQRILEMNDKYVKKEMCHQSTETVSSFAEENVHERSLAETTHLYEQALEEIAKLKEQCSTLQNLKTECSRCADGESKSEVDEIAVQLDDVFRQLDKCTIERDEYKSQVELLEVEKNKIACQCEELKSEIAELKASIPQAVARANDSTASNVEDTVNFSDGERAGRKEDLNYRLANTTSVPGKTLKQICLEAACKLMIVNMNEGIEKIKPDSSPAQ", "length": 927, "header": "tr|A0A8V0YQ55-1|A0A8V0YQ55_CHICK Isoform 1 of MORC family CW-type zinc finger 4 OS=Gallus gallus OX=9031 GN=MORC4 PE=1 SV=1 CANONICAL=A0A8V0YQ55-1" }, "locus": { "chromosome": "1", "start_pos": 106750723, "end_pos": 106726393, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031340.1", "url": "https://www.ensembl.org/id/ENSGALT00010031340.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018276.1", "url": "https://www.ensembl.org/id/ENSGALP00010018276.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:418513", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418513", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A096MIX0-1", "protein_name": "MORC family CW-type zinc finger 3", "gene_name": "Morc3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAVQPPTGIRLSALCPKFLHTNSTSHTWPFSAVAELIDNAYDPDVNAKQIWIDKTVISDHICLTFTDNGNGMTADKLHKMLSFGFSDKVTVNGHVPVGLYGNGFKSGSMRLGRDAMVFTKNGDTMSVGFLSQTYLEVIKAEHVVVPIVTFNKHRQMIYLTESKASLAAMLEHSLFSTEQKLLAELDAIMGKKGTRIIIWNLRSYKNATEFDFEKDKYDIRIPEDLDEVAGKKGYKKQERMDQIAPESDYSLRAYCSILYLKPRMQIIIRGQKVKTQLVSKSLAYIERDVYRPKFLTKTVRITFGFNCRNKDHYGIMMYHKNRLIKAYEKVGCQLKANNMGVGVVGVIECNFLKPTHNKQDFDYTNEYRLTILALGEKLNDYWNEMKVKKNSEYPLNLPVEDIQKRPDQTWVQCDACLKWRKLPDGIDQLPEKWYCSNNPDPQFRNCEVPEEPEDEDLVHPTYEKTYKKTKEKFRIRQPEMLPRILPRINHEIVYQTSVSSPSFSPVKESVPRPHISEVASPFAARIINNHLVSAQPEPESNSLKRRLSVRSSILNAKTRRLSNPPIENSSYKNDDDEDVIILEENSTPKPAVDLDVRSDIEVKSEQSHAEQTGIEVELVSSPQPGVQASSTSTATSRCDQGTAASTQTEAPGLMVKKEESMEEDMDVRNGRAALSCVSAEVKVQETSAESADAAGHQLQELRSELLLVTQERDDYKRKCQVFADQIQVLQRRLLEMNDQCVKKEMCHQSTEMDAVFLLGSVNGQSESPGHVGSQYQQALEEIERLKKQCSALQHVKGECSQSSCTESKSEMDEMAVQLDDVFRQLDKCTIERDQYRSEVQLLEMEKSHMHSRCEELKTEVEQLKSTSQQAGADVSTSSSAEEAVSYVDGESLKLRSLRVNVGQLLAMIVPDLDLQQVNYDVDVVDEILGQVVEQMSEISSS", "length": 941 }, "evidence": [ { "id": "A0A8V0YQ55", "url": "https://omabrowser.org/oma/group/A0A8V0YQ55/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F7BJB9-1", "protein_name": "MORC family CW-type zinc finger protein 3", "gene_name": "Morc3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAQPPTGIRLSALCPKFLHTNSTSHTWPFSAVAELIDNAYDPDVNAKQIWIDKTVISDHICLTFTDNGNGMTADKLHKMLSFGFSDKVTMNGHVPVGLYGNGFKSGSMRLGKDAMVFTKNGETMSVGFLSQTYLEVIKAEHVVVPIVTFNKHRQMINLTESKASLAAILEHSLFSTEQKLLAELNAIMGKKGTRIIIWNLRSYKNATEFDFEKDKYDIRIPEDLDETAGRKGYKKQERMDQIAPESDYSLRAYCSILYLKPRMQIIIRGQKVKTQLVSKSLAYIERDVYRPKFLTRTVRITFGFNCRNKDHYGIMMYHKNRLIKAYEKVGCQLKANNMGVGVVGIIECNFLKPTHNKQDFDYTNEYRLTILALGEKLNDYWNEMKVKKNAEYPVNLPVEDIQKRPDQTWVQCDACLKWRKLPDGIDQLPEKWYCSNNPDPQFRNCEVPEEPEDEDLVHPTYEKTYKKTSKERFRIRQPEILPRILPQINPELLYQTSVSSQSFSPVKESVPRPHLSEVTSPFAARIINLNLASPASEPENSSMKRKLGVHSSILNAKTRRLSNPPVENSSYKNDDDEDVIILEENSTPKPAVDLEVKSDIEVKSEQSHTEQSGIHVDLVSSPKPCVQASSTSTSTSRSDPGITVSTQTDAPGLTVKKEESMEEDMGVRNGTATLSCVGTEAKVQETSAESVDATSHQLQELRSELLVVTQERDDYKRQCQMFTDQIQVLQQRLLEMNDKCVKKEKCHQSTETDAVFLLDSVNGQAESLDHLGSQYQQALQEIERLKRQCSALQQVKSECSQASCTESKSEVDEMAVQLDDVFRQLDKCTIERDQYKNEVQLLEIEKSHIHSQCEELQTEVEQLKSTGQQAAADGSTASNAEEPVSYVDGESLKLRSLRVNVGQLLAMIVPDLDLQQVNYDVDVVDEILGQVVEQMSEISST", "length": 942 }, "evidence": [ { "id": "A0A8V0YQ55", "url": "https://omabrowser.org/oma/group/A0A8V0YQ55/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q14149-1", "protein_name": "MORC family CW-type zinc finger protein 3", "gene_name": "MORC3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": 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{ "uniprot_canonical_ac": "A0A8V0YNN9-1", "uniprot_ac": "A0A8V0YNN9", "uniprot_id": "A0A8V0YNN9_CHICK", "mass": { "chemical_mass": 121760.0, "monoisotopic_mass": 121760.0 }, "refseq": { "ac": "XP_040559290", "name": "collagen alpha-1(VI) chain isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040559290" }, "gene_names": [ { "name": "COL6A1", "type": "recommended", "evidence": [ { "id": "A0A8V0YNN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNN9" } ] }, { "name": "COL6A1", "type": "synonym", "evidence": [ { "id": "XP_040559290", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040559290" } ] } ], "protein_names": [ { "name": "Collagen alpha-1(VI) chain", "type": "recommended", "evidence": [ { "id": "A0A8V0YNN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNN9/entry#names_and_taxonomy" } ] }, { "name": "collagen alpha-1(VI) chain isoform X1", "type": "synonym", "evidence": [ { "id": "XP_040559290", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040559290" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052538.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040559290", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040559290" } ] }, { "annotation": "Collagen VI acts as a cell-binding protein.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNN9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNN9#function" }, { "database": "UniProtKB", "id": "ARBA00043858", "url": "https://www.uniprot.org/uniprotkb/ARBA00043858#function" }, { "database": "UniProtKB", "id": "A0A8V0YHC1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHC1#function" }, { "database": "UniProtKB", "id": "A0A8V0YQF4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQF4#function" }, { "database": "UniProtKB", "id": "A0A8V0YQG4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQG4#function" }, { "database": "UniProtKB", "id": "A0A8V0YVH3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YVH3#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNN9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNN9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "COL6A1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNN9", "locus": { "chromosome": "7", "start_pos": 6795975, "end_pos": 6774658, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010014310", "url": "https://www.ensembl.org/id/ENSGALG00010014310" } ] } } ], "crossref": [ { "id": "A0A8V0YNN9", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YNN9", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd01480", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01480", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "396000", "url": 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"Protein" ] }, { "id": "A0A8V0YHC1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHC1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHC1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHC1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YNN9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNN9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YNN9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNN9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQF4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQF4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQF4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQF4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQG4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQG4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQG4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQG4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YVH3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YVH3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YVH3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YVH3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQQAAFLQSPLGSAQGSEPPGRSWGTAESFGRSARVQGAQKDSEEKRRLASESARTALVPPSIPAAESPPRPLPPARSSFPGSQALKPPPDPDPASPSFLPSLQLDVNLSPATWGCTTPSWRCCFFWGVPGLSRLKSTPVSSGLRLCRGPSGKRCCATLLCLPSDCPVDLFFVLDTSESVALRVKPFGDLVAQVKDFTNRFIDKLTERYFRCDRFLAWNAGALHYSDSVVIIKDLTAMPSGRAELKNSVSAINYIGKGTHTDCAIKQGIERLLLGGSHLKENKYLIVVTDGHPLEGYKEPCGGLDDAANEAKHLGIKVFSVAISPHHLDQRLNIIATDHAYRRNFTATSLKPTRDLDVEETINNIIEMIKDNMEQSCCSFECHPPRGPPGPPGDPGHEGERGKPGLPGQKGDAGDPGRPGDMGPVGYQGMKGDKGSRGEKGSRGAKGAKGEKGKRGIDGIDGMKGEAGYPGLPGCKGSPGFDGTQGPPGPKGDPGAYGPKGGKGEPGEDGKPGRQGIPGSPGEKGAPGNRGEPGPLGETGDEGSPGADGPPGERGSNGERGPPGSPGDRGPRGDLGEPGPPGDQGREGPLGPPGDQGEPGPPGPKGYRGDDGPRGNEGPKGSPGAPGLPGDPGLMGERGEDGPPGNGTIGFPGAPGQQGDRGDPGINGTKGYVGPKGDEGEAGDPGNDNPTAGPSGIKGAKGHRGPEGRPGPPGPVGPPGPDECEILDIIMKMCSCCECTCGPVDLLFVLDSSESIGLQNFQIAKDFIIKVIDRLSKDERVKFEPGESRVGVVQYSHNNTQELVAMGDANIDNIGALKQAVKNLKWIAGGTHTGEALQFSKENLLRRFTSNNNVAIVITDGRSDTLRDRTPLTSLCEVTPVVSLGIGDIFRNNPNPDQLNDIACLGMPRRQGLSIQRDNYAELLDDSFLQNITSYVCREKKCPDYTCPITFANPADIMLLVDSSTSVGSKNFDTTKNFVKRLAERFLEASKPAEDSVRVSVVQYSGRNQQKVEVPFQRNYTVIAKAVDNMEFMNEATDVNAALQYIMGLYQRSSRAGAKKKVLVFSDGNSQGITARAIERTVQEVQQAGIEVYVLAVGSQVNEPNVRVLVTGKSTNYDVAYGERHLFRVPDYTSLLRGVFYQTVSRKIAVD", "length": 1151, "header": "tr|A0A8V0YNN9-1|A0A8V0YNN9_CHICK Isoform 1 of Collagen alpha-1(VI) chain OS=Gallus gallus OX=9031 GN=COL6A1 PE=3 SV=1 CANONICAL=A0A8V0YNN9-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YHC1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNN9/entry#A0A8V0YHC1-1", "sequence": { "sequence": "MGLHDSFLALLLLLGGAWAQQAEINARVLRAQDCPVDLFFVLDTSESVALRVKPFGDLVAQVKDFTNRFIDKLTERYFRCDRFLAWNAGALHYSDSVVIIKDLTAMPSGRAELKNSVSAINYIGKGTHTDCAIKQGIERLLLGGSHLKENKYLIVVTDGHPLEGYKEPCGGLDDAANEAKHLGIKVFSVAISPHHLDQRLNIIATDHAYRRNFTATSLKPTRDLDVEETINNIIEMIVSADCSPAQLTPGERGKPGLPGQKGDAGDPAVSRMGPMCRGIPQVLLTAALVLSVPQGEAGYPGLPGCKGSPGFDHGDQNPPLGTDVSSCVFVKGEPGEDGKPGRQGIPGSPGEKGAPGNRGEPGPLGETGDEGSPGADGPPGERGSNGERGPPGSPGDRGPRGDLGEPGPPGDQGREGPLGPPGDQGEPGPPGPKGYRGDDGPRGNEGPKGSPGAPGLPGDPGLMGERGEDGPPGNGTIGFPGAPGQQGDRGDPGINGTKGYVGPKGDEGEAGDPGNDNPTAGPSGIKGAKGHRGPEGRPVSKGSRRAPAPATSPHMCFTAECTCGPVDLLFVLDSSESIGLQNFQIAKDFIIKVIDRLSKDERVKFEPGESRVGVVQYSHNNTQELVAMGDANIDNIGALKQAVKNLKWIAGGTHTGEALQFSKENLLRRFTSNNNVAIVITDGRSDTLRDRTPLTSLCEVTPVVSLGIGDIFRNNPNPDQLNDIACLGMPRRQGLSIQRDNYAELLDDSFLQNITSYVCREKKCPDYTCPITFANPADIMLLVDSSTSVGSKNFDTTKNFVKRLAERFLEASKPAEDSVRVSVVQYSGRNQQKVEVPFQRNYTVIAKAVDNMEFMNEATDVNAALQYIMGLYQRSSRAGAKKKVLVFSDGNSQGITARAIERTVQEVQQAGIEVYVLAVGSQVNEPNVRVLVTGKSTNYDVAYGERHLFRVPDYTSLLRGVFYQTVSRKIAVD", "length": 973, "header": "tr|A0A8V0YHC1-1|A0A8V0YNN9_CHICK Computationally mapped isoform of Collagen alpha-1(VI) chain OS=Gallus gallus OX=9031 GN=COL6A1 PE=3 SV=1 CANONICAL=A0A8V0YNN9-1" }, "locus": { "chromosome": "7", "start_pos": 6794550, "end_pos": 6775013, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034484.1", "url": "https://www.ensembl.org/id/ENSGALT00010034484.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020260.1", "url": "https://www.ensembl.org/id/ENSGALP00010020260.1" } ] } }, { "isoform_ac": "A0A8V0YNN9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNN9/entry#A0A8V0YNN9-1", "sequence": { "sequence": "MQQAAFLQSPLGSAQGSEPPGRSWGTAESFGRSARVQGAQKDSEEKRRLASESARTALVPPSIPAAESPPRPLPPARSSFPGSQALKPPPDPDPASPSFLPSLQLDVNLSPATWGCTTPSWRCCFFWGVPGLSRLKSTPVSSGLRLCRGPSGKRCCATLLCLPSDCPVDLFFVLDTSESVALRVKPFGDLVAQVKDFTNRFIDKLTERYFRCDRFLAWNAGALHYSDSVVIIKDLTAMPSGRAELKNSVSAINYIGKGTHTDCAIKQGIERLLLGGSHLKENKYLIVVTDGHPLEGYKEPCGGLDDAANEAKHLGIKVFSVAISPHHLDQRLNIIATDHAYRRNFTATSLKPTRDLDVEETINNIIEMIKDNMEQSCCSFECHPPRGPPGPPGDPGHEGERGKPGLPGQKGDAGDPGRPGDMGPVGYQGMKGDKGSRGEKGSRGAKGAKGEKGKRGIDGIDGMKGEAGYPGLPGCKGSPGFDGTQGPPGPKGDPGAYGPKGGKGEPGEDGKPGRQGIPGSPGEKGAPGNRGEPGPLGETGDEGSPGADGPPGERGSNGERGPPGSPGDRGPRGDLGEPGPPGDQGREGPLGPPGDQGEPGPPGPKGYRGDDGPRGNEGPKGSPGAPGLPGDPGLMGERGEDGPPGNGTIGFPGAPGQQGDRGDPGINGTKGYVGPKGDEGEAGDPGNDNPTAGPSGIKGAKGHRGPEGRPGPPGPVGPPGPDECEILDIIMKMCSCCECTCGPVDLLFVLDSSESIGLQNFQIAKDFIIKVIDRLSKDERVKFEPGESRVGVVQYSHNNTQELVAMGDANIDNIGALKQAVKNLKWIAGGTHTGEALQFSKENLLRRFTSNNNVAIVITDGRSDTLRDRTPLTSLCEVTPVVSLGIGDIFRNNPNPDQLNDIACLGMPRRQGLSIQRDNYAELLDDSFLQNITSYVCREKKCPDYTCPITFANPADIMLLVDSSTSVGSKNFDTTKNFVKRLAERFLEASKPAEDSVRVSVVQYSGRNQQKVEVPFQRNYTVIAKAVDNMEFMNEATDVNAALQYIMGLYQRSSRAGAKKKVLVFSDGNSQGITARAIERTVQEVQQAGIEVYVLAVGSQVNEPNVRVLVTGKSTNYDVAYGERHLFRVPDYTSLLRGVFYQTVSRKIAVD", "length": 1151, "header": "tr|A0A8V0YNN9-1|A0A8V0YNN9_CHICK Isoform 1 of Collagen alpha-1(VI) chain OS=Gallus gallus OX=9031 GN=COL6A1 PE=3 SV=1 CANONICAL=A0A8V0YNN9-1" }, "locus": { "chromosome": "7", "start_pos": 6794550, "end_pos": 6774675, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034496.1", "url": "https://www.ensembl.org/id/ENSGALT00010034496.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020269.1", "url": "https://www.ensembl.org/id/ENSGALP00010020269.1" } ] } }, { "isoform_ac": "A0A8V0YQF4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNN9/entry#A0A8V0YQF4-1", "sequence": { "sequence": "MGLHDSFLALLLLLGGAWAQQAEINARVLRAQDCPVDLFFVLDTSESVALRVKPFGDLVAQVKDFTNRFIDKLTERYFRCDRFLAWNAGALHYSDSVVIIKDLTAMPSGRAELKNSVSAINYIGKGTHTDCAIKQGIERLLLGGSHLKENKYLIVVTDGHPLEGYKEPCGGLDDAANEAKHLGIKVFSVAISPHHLDQRLNIIATDHAYRRNFTATSLKPTRDLDVEETINNIIEMIKDNMEQSCCSFECHPPRGPPGPPGDPGHEGERGKPGLPGQKGDAGDPGRPGDMGPVGYQGMKGDKGSRGEKGSRGAKGAKGEKGKRGIDGIDGMKGEAGYPGLPGCKGSPGFDGTQGPPGPKGDPGAYGPKGGKGEPGEDGKPGRQGIPGSPGEKGAPGNRGEPGPLGETGDEGSPGADGPPGERGSNGERGPPGSPGPKGYRGDDGPRGNEGPKGSPGAPGLPGDPGLMGERGEDGPPGNGTIGFPGAPGQQGDRGDPGINGTKGYVGPKGDEGEAGDPGNDNPTAGPSGIKGAKGHRGPEGRPGPPGPVGPPGPDECEILDIIMKMCSCCECTCGPVDLLFVLDSSESIGLQNFQIAKDFIIKVIDRLSKDERVKFEPGESRVGVVQYSHNNTQELVAMGDANIDNIGALKQAVKNLKWIAGGTHTGEALQFSKENLLRRFTSNNNVAIVITDGRSDTLRDRTPLTSLCEVTPVVSLGIGDIFRNNPNPDQLNDIACLGMPRRQGLSIQRDNYAELLDDSFLQNITSYVCREKKCPDYTCPITFANPADIMLLVDSSTSVGSKNFDTTKNFVKRLAERFLEASKPAEDSVRVSVVQYSGRNQQKVEVPFQRNYTVIAKAVDNMEFMNEATDVNAALQYIMGLYQRSSRAGAKKKVLVFSDGNSQGITARAIERTVQEVQQAGIEVYVLAVGSQVNEPNVRVLVTGKSTNYDVAYGERHLFRVPDYTSLLRGVFYQTVSRKIAVD", "length": 983, "header": "tr|A0A8V0YQF4-1|A0A8V0YQF4_CHICK Computationally mapped isoform of Collagen alpha-1(VI) chain OS=Gallus gallus OX=9031 GN=COL6A1 PE=3 SV=1 CANONICAL=A0A8V0YNN9-1" }, "locus": { "chromosome": "7", "start_pos": 6794550, "end_pos": 6775013, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034475.1", "url": "https://www.ensembl.org/id/ENSGALT00010034475.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020253.1", "url": "https://www.ensembl.org/id/ENSGALP00010020253.1" } ] } }, { "isoform_ac": "A0A8V0YQG4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNN9/entry#A0A8V0YQG4-1", "sequence": { "sequence": "MGLHDSFLALLLLLGGAWAQQAEINARVLRAQDCPVDLFFVLDTSESVALRVKPFGDLVAQVKDFTNRFIDKLTERYFRCDRFLAWNAGALHYSDSVVIIKDLTAMPSGRAELKNSVSAINYIGKGTHTDCAIKQGIERLLLGGSHLKENKYLIVVTDGHPLEGYKEPCGGLDDAANEAKHLGIKVFSVAISPHHLDQRLNIIATDHAYRRNFTATSLKPTRDLDVEETINNIIEMIKDNMEQSCCSFECHPPRGPPGPPGDPGHEGERGKPGLPGQKGDAGDPGRPGDMGPVGYQGMKGDKGSRGEKGSRGAKGAKGEKGKRGIDGIDGMKGEAGYPGLPGCKGSPGFDGTQGPPGPKGDPGAYGPKGGKGEPGEDGKPGRQGIPGSPGEKGAPGNRGEPGPLGETGDEGSPGPKGYRGDDGPRGNEGPKGSPGAPGLPGDPGLMGERGEDGPPGNGTIGFPGAPGQQGDRGDPGINGTKGYVGPKGDEGEAGDPGNDNPTAGPSGIKGAKGHRGPEGRPGPPGPVGPPGPDECEILDIIMKMCSCCECTCGPVDLLFVLDSSESIGLQNFQIAKDFIIKVIDRLSKDERVKFEPGESRVGVVQYSHNNTQELVAMGDANIDNIGALKQAVKNLKWIAGGTHTGEALQFSKENLLRRFTSNNNVAIVITDGRSDTLRDRTPLTSLCEVTPVVSLGIGDIFRNNPNPDQLNDIACLGMPRRQGLSIQRDNYAELLDDSFLQNITSYVCREKKCPDYTCPITFANPADIMLLVDSSTSVGSKNFDTTKNFVKRLAERFLEASKPAEDSVRVSVVQYSGRNQQKVEVPFQRNYTVIAKAVDNMEFMNEATDVNAALQYIMGLYQRSSRAGAKKKVLVFSDGNSQGITARAIERTVQEVQQAGIEVYVLAVGSQVNEPNVRVLVTGKSTNYDVAYGERHLFRVPDYTSLLRGVFYQTVSRKIAVD", "length": 962, "header": "tr|A0A8V0YQG4-1|A0A8V0YQG4_CHICK Computationally mapped isoform of Collagen alpha-1(VI) chain OS=Gallus gallus OX=9031 GN=COL6A1 PE=3 SV=1 CANONICAL=A0A8V0YNN9-1" }, "locus": { "chromosome": "7", "start_pos": 6794550, "end_pos": 6775013, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034487.1", "url": "https://www.ensembl.org/id/ENSGALT00010034487.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020263.1", "url": "https://www.ensembl.org/id/ENSGALP00010020263.1" } ] } }, { "isoform_ac": "A0A8V0YVH3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNN9/entry#A0A8V0YVH3-1", "sequence": { "sequence": "MGLHDSFLALLLLLGGAWAQQAEINARVLRAQDCPVDLFFVLDTSESVALRVKPFGDLVAQVKDFTNRFIDKLTERYFRCDRFLAWNAGALHYSDSVVIIKDLTAMPSGRAELKNSVSAINYIGKGTHTDCAIKQGIERLLLGGSHLKENKYLIVVTDGHPLEGYKEPCGGLDDAANEAKHLGIKVFSVAISPHHLDQRLNIIATDHAYRRNFTATSLKPTRDLDVEETINNIIEMIKDNMEQSCCSFECHPPRGPPGPPGDPGHEGERGKPGLPGQKGDAGDPGRPGDMGPVGYQGMKGDKGSRGEKGSRGAKGAKGEKGKRGIDGIDGMKGEAGYPGLPGCKGSPGFDGTQGPPGPKGDPGAYGPKGGKGEPGEDGKPGRQGIPGSPGEKGAPGNRGEPGPLGETGDEGSPGADGPPGERGSNGERGPPGSPGDRGPRGDLGEPGPPGDQGREGPLGPPGDQGEPGPPGPKGYRGDDGPRGNEGPKGSPGAPGLPGDPGLMGERGEDGPPGNGTIGFPGAPGQQGDRGDPGINGTKGYVGPKGDEGEAGDPGNDNPTAGPSGIKGAKGHRGPEGRPGPPGPVGPPGPDECEILDIIMKMCSCCECTCGPVDLLFVLDSSESIGLQNFQIAKDFIIKVIDRLSKDERVKFEPGESRVGVVQYSHNNTQELVAMGDANIDNIGALKQAVKNLKWIAGGTHTGEALQFSKENLLRRFTSNNNVAIVITDGRSDTLRDRTPLTSLCEVTPVVSLGIGDIFRNNPNPDQLNDIACLGMPRRQGLSIQRDNYAELLDDSFLQNITSYVCREKKCPDYTCPITFANPADIMLLVDSSTSVGSKNFDTTKNFVKRLAERFLEASKPAEDSVRVSVVQYSGRNQQKVEVPFQRNYTVIAKAVDNMEFMNEATDVNAALQYIMGLYQRSSRAGAKKKVLVLRSTCWQWAAKSTSPMSASW", "length": 952, "header": "tr|A0A8V0YVH3-1|A0A8V0YVH3_CHICK Computationally mapped isoform of Collagen alpha-1(VI) chain OS=Gallus gallus OX=9031 GN=COL6A1 PE=3 SV=1 CANONICAL=A0A8V0YNN9-1" }, "locus": { "chromosome": "7", "start_pos": 6794425, "end_pos": 6775013, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034466.1", "url": "https://www.ensembl.org/id/ENSGALT00010034466.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020246.1", "url": "https://www.ensembl.org/id/ENSGALP00010020246.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "D3ZUL3-1", "protein_name": "Collagen alpha-1(VI) chain", "gene_name": "Col6a1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVTRRPAGNMRLAHTLLPLLLQACWVAAQDIQGSRAIAFQDCPVDLFFVLDTSESVALRLKPYGALVDKVKSFTKRFIDNLRDRYYRCDRNLVWNAGALHYSDEVEIIRGLMRMPSGRDELKASIDAVKYFGKGTYTDCAIKKGLEELLIGGSHLKENKYLIVVTDGHPLEGYKEPCGGLEDAVNEAKHLGIKVFSVAITPDHLEPRLSIIATDHTYRRNFTAADWGHSRDAEETISQTIDTIVDMIKNNVEQVCCTFECQAARGPPGPRGDPGYEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGPKGYKGEKGKRGIDGVDGMKGETGYPGLPGCKGSPGFDGIQGPPGPKGDAGAFGLKGEKGEAGAEGEAGRPGNSGPPGDEGEPGEPGPPGEKGEAGDEGNAGPDGAPGERGGPGERGPRGTPGVRGPRGDPGEAGPQGDQGREGPVGIPGDPGESGPIGPKGYRGDEGPPGPEGLRGAPGPVGPPGDPGLMGERGEDGPPGNGTEGFPGFPGYPGNRGPPGINGTKGYPGLKGDEGEAGDPGEDNNDVSPRGVKGAKGYRGPEGPQGPPGHVGPPGPDECEILDIIMKMCSCCECTCGPIDILFVLDSSESIGLQNFEIAKDFIIKVIDRLSKDELVKFEPGQSHAGVVQYSHNQMQEHVDMRSPNVRNAQDFKEAVKKLQWMAGGTFTGEALQYTRDRLLPPTQNNRIALVITDGRSDTQRDTTPLSVLCGSDIQVVSVGIKDVFGFVAGSDQLNVISCQGLSQSRPGISLVKENYAELLDDGFLKNITAQICIDKKCPDYTCPITFSSPTDITILLDSSASVGSHNFETTKVFAKRLAERFLSAGREDPTQVVRVAVVQYSGQGQQQPGRASLQFQQNYTVLASSVDSMDFINDATDVNDALSYVTRFYRENSSGATKKRVLLFSDGNSQGATAEAIEKAVQEAQRGGIEIFVMVVGPQVNEPHIRVLVTGKTAEYDVAFGERHLFRVPNYQALLRGVLYQTVSRKVALG", "length": 1034 }, "evidence": [ { "id": "A0A8V0YNN9", "url": "https://omabrowser.org/oma/group/A0A8V0YNN9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E1BI98-1", "protein_name": "Collagen alpha-1(VI) chain", "gene_name": "COL6A1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MRLPRALLPLLLQACWASAQDDPVASRAIAFQDCPVDLFFVLDTSESVALRLKPYGALVDKVKSFTKRFIDNLNDRYYRCDRNLVWNAGALHYSDEVEIIRGLTRMPSGRDELKSSVDAVKYFGKGTYTDCAIKKGLEELLVGGSHLKENKYLVVVTDGHPLEGYKEPCGGLEDAVNEAKHLGIKVFSVAITPDHLEPRLSIIATDHTYRRNFTAADWGQSRDAEEVISQTIDTITDMIKNNVEQVCCSFECQPARGPPGPRGDPGYEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGPKGYKGEKGKRGMDGVDGMKGETGFPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGQKGEPGADGEPGRPGSTGPPGDEGEPGEPGPPGEKGEAGDEGNAGPDGAPGERGGPGERGPRGTPGARGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDEGPPGTEGPKGAPGPAGPPGDPGLMGERGEDGPPGNGTEGFPGFPGYPGSRGPPGINGTKGYPGLKGDEGEAGDPGEDNNDIAARGAKGAKGYRGPEGPQGPPGHVGPPGPDECEILDIIMKMCSCCECKCGPIDILFVLDSSESIGLQNFEIAKDFIVKVIDRLSKDELVKFEPGQSHAGVVQYSHNQMQEHVDLRDPNIRNAQDLKEAIKKLQWMGGGTFTGEALQYTRSRLLPPTPNNRIALVITDGRSDTQRDTTPLSVLCGPDIQVVSVGIKDVFGLAAGSDQLNVISCQGLAPQGRPGISLVKENYAELLDDGFLKNITAQICIDKKCPDYSCPITFSSPADITILLDGSASVGSHNFDITKRFAKRLAERFLTASRTDPGQDVRVAVVQYSGTGQQRPERAALQFLQNYTVLANTVDSMDFFNDATDVMDALGYVTRFYREASSNAAKKRLLLFSDGNSQGATPAAIEKAVQEAQRAGVEIFAVVVGRQVNEPHVRVLVTGKAAEYDVVFGERHLFRVPSYQALLRGVFYQTVSRKVALD", "length": 1027 }, "evidence": [ { "id": "A0A8V0YNN9", "url": "https://omabrowser.org/oma/group/A0A8V0YNN9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P12109-1", "protein_name": "Collagen alpha-1(VI) chain", "gene_name": "COL6A1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRAARALLPLLLQACWTAAQDEPETPRAVAFQDCPVDLFFVLDTSESVALRLKPYGALVDKVKSFTKRFIDNLRDRYYRCDRNLVWNAGALHYSDEVEIIQGLTRMPGGRDALKSSVDAVKYFGKGTYTDCAIKKGLEQLLVGGSHLKENKYLIVVTDGHPLEGYKEPCGGLEDAVNEAKHLGVKVFSVAITPDHLEPRLSIIATDHTYRRNFTAADWGQSRDAEEAISQTIDTIVDMIKNNVEQVCCSFECQPARGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAGNGTEGFPGFPGYPGNRGAPGINGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPGPDECEILDIIMKMCSCCECKCGPIDLLFVLDSSESIGLQNFEIAKDFVVKVIDRLSRDELVKFEPGQSYAGVVQYSHSQMQEHVSLRSPSIRNVQELKEAIKSLQWMAGGTFTGEALQYTRDQLLPPSPNNRIALVITDGRSDTQRDTTPLNVLCSPGIQVVSVGIKDVFDFIPGSDQLNVISCQGLAPSQGRPGLSLVKENYAELLEDAFLKNVTAQICIDKKCPDYTCPITFSSPADITILLDGSASVGSHNFDTTKRFAKRLAERFLTAGRTDPAHDVRVAVVQYSGTGQQRPERASLQFLQNYTALASAVDAMDFINDATDVNDALGYVTRFYREASSGAAKKRLLLFSDGNSQGATPAAIEKAVQEAQRAGIEIFVVVVGRQVNEPHIRVLVTGKTAEYDVAYGESHLFRVPSYQALLRGVFHQTVSRKVALG", "length": 1028 }, "evidence": [ { "id": "A0A8V0YNN9", "url": "https://omabrowser.org/oma/group/A0A8V0YNN9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q04857-1", "protein_name": "Collagen alpha-1(VI) chain", "gene_name": "Col6a1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRLAHALLPLLLQACWVATQDIQGSKAIAFQDCPVDLFFVLDTSESVALRLKPYGALVDKVKSFTKRFIDNLRDRYYRCDRNLVWNAGALHYSDEVEIIRGLTRMPSGRDELKASVDAVKYFGKGTYTDCAIKKGLEELLIGGSHLKENKYLIVVTDGHPLEGYKEPCGGLEDAVNEAKHLGIKVFSVAITPDHLEPRLSIIATDHTYRRNFTAADWGHSRDAEEVISQTIDTIVDMIKNNVEQVCCSFECQAARGPPGPRGDPGYEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGPKGYKGEKGKRGIDGVDGMKGETGYPGLPGCKGSPGFDGIQGPPGPKGDAGAFGMKGEKGEAGADGEAGRPGNSGSPGDEGDPGEPGPPGEKGEAGDEGNAGPDGAPGERGGPGERGPRGTPGVRGPRGDPGEAGPQGDQGREGPVGIPGDSGEAGPIGPKGYRGDEGPPGPEGLRGAPGPVGPPGDPGLMGERGEDGPPGNGTEGFPGFPGYPGNRGPPGLNGTKGYPGLKGDEGEVGDPGEDNNDISPRGVKGAKGYRGPEGPQGPPGHVGPPGPDECEILDIIMKMCSCCECTCGPIDILFVLDSSESIGLQNFEIAKDFIIKVIDRLSKDELVKFEPGQSHAGVVQYSHNQMQEHVDMRSPNVRNAQDFKEAVKKLQWMAGGTFTGEALQYTRDRLLPPTQNNRIALVITDGRSDTQRDTTPLSVLCGADIQVVSVGIKDVFGFVAGSDQLNVISCQGLSQGRPGISLVKENYAELLDDGFLKNITAQICIDKKCPDYTCPITFSSPADITILLDSSASVGSHNFETTKVFAKRLAERFLSAGRADPSQDVRVAVVQYSGQGQQQPGRAALQFLQNYTVLASSVDSMDFINDATDVNDALSYVTRFYREASSGATKKRVLLFSDGNSQGATAEAIEKAVQEAQRAGIEIFVVVVGPQVNEPHIRVLVTGKTAEYDVAFGERHLFRVPNYQALLRGVLYQTVSRKVALG", "length": 1025 }, "evidence": [ { "id": "A0A8V0YNN9", "url": "https://omabrowser.org/oma/group/A0A8V0YNN9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 9, "go_terms": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNN9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNN9" } ], "pmid": "" }, { "name": "collagen type VI trimer", "id": "GO:0005589", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005589", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNN9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNN9" } ], "pmid": "" }, { "name": "intracellular vesicle", "id": "GO:0097708", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097708", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNN9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNN9" } ], "pmid": "" }, { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNN9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNN9" } ], "pmid": "" }, { "name": "lysosome", "id": "GO:0005764", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005764", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNN9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNN9" } ], "pmid": "" }, { "name": "sarcolemma", "id": "GO:0042383", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042383", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNN9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNN9" } ], "pmid": "" }, { "name": "basement membrane", "id": "GO:0005604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005604", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNN9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNN9" } ], "pmid": "" }, { "name": "myofibril", "id": "GO:0030016", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030016", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNN9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNN9" } ], "pmid": "" }, { "name": "sarcoplasmic reticulum", "id": "GO:0016529", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016529", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNN9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNN9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "cell adhesion", "id": "GO:0007155", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007155", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNN9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNN9" } ], "pmid": "" }, { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNN9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNN9" } ], "pmid": "" }, { "name": "tissue development", "id": "GO:0009888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009888", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNN9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNN9" } ], "pmid": "" }, { "name": "anatomical structure morphogenesis", "id": "GO:0009653", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009653", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNN9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNN9" } ], "pmid": "" }, { "name": "endodermal cell differentiation", "id": "GO:0035987", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035987", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNN9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNN9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "collagen binding", "id": "GO:0005518", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005518", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNN9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNN9" } ], "pmid": "" }, { "name": "platelet-derived growth factor binding", "id": "GO:0048407", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048407", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNN9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNN9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1019, "end_pos": 1021, "annotation": "n_glycosylation_sequon" }, { "start_pos": 108, "end_pos": 110, "annotation": "n_glycosylation_sequon" }, { "start_pos": 344, "end_pos": 346, "annotation": "n_glycosylation_sequon" }, { "start_pos": 646, "end_pos": 648, "annotation": "n_glycosylation_sequon" }, { "start_pos": 667, "end_pos": 669, "annotation": "n_glycosylation_sequon" }, { "start_pos": 798, "end_pos": 800, "annotation": "n_glycosylation_sequon" }, { "start_pos": 931, "end_pos": 933, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YNN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNN9" }, { "id": "PS50234", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50234" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "VWFA", "eco_id": "ECO_0000259", "start_pos": 169, "end_pos": 365, "start_aa": "Asp", "end_aa": "Ile", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1019, "end_pos": 1021 }, { "start_pos": 108, "end_pos": 110 }, { "start_pos": 344, "end_pos": 346 }, { "start_pos": 646, "end_pos": 648 }, { "start_pos": 667, "end_pos": 669 }, { "start_pos": 798, "end_pos": 800 }, { "start_pos": 931, "end_pos": 933 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": 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"o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YNR8-1", "uniprot_ac": "A0A8V0YNR8", "uniprot_id": "A0A8V0YNR8_CHICK", "mass": { "chemical_mass": 65056.0, "monoisotopic_mass": 65056.0 }, "refseq": {}, "gene_names": [ { "name": "AFG1L", "type": "recommended", "evidence": [ { "id": "A0A8V0YNR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNR8" } ] } ], "protein_names": [ { "name": "AFG1 like ATPase", "type": "synonym", "evidence": [ { "id": "A0A8V0YNR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNR8/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNR8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNR8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "AFG1L", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNR8", "locus": { "chromosome": "3", "start_pos": 67087553, "end_pos": 67151746, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010014346", "url": "https://www.ensembl.org/id/ENSGALG00010014346" } ] } } ], "crossref": [ { "id": "A0A8V0YNR8", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YNR8", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR005654", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005654", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YHF5", "url": "https://www.orthodb.org/?gene=A0A8V0YHF5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YHG0", "url": "https://www.orthodb.org/?gene=A0A8V0YHG0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YNR8", "url": "https://www.orthodb.org/?gene=A0A8V0YNR8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12169", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12169", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12169:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12169:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03969", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03969", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YHF5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHF5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHF5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHF5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHG0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHG0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHG0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHG0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YNR8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNR8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YNR8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNR8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVGLLAPDCQCPFTGIYICLFVHCIVPFCQVVWQTEAGGCSGATRPLRCTLRHHSRCQSQRPHPGTPFPSSPRALRRGGRAGKMAAPVSPLVTARCLLRASARRVVRLLPARALPRGIDYSRSCSVVNDFCSLLHNAAYASQAADEKVVLGTLTDANSRALLVCDGPLEHYDFLIKQEELRNDEQQRRVVQHLQKLHESLKGYSISSQNFLSKLFAKNKPPKGLYVYGDVGTGKTMVMDMFYSHLKVERKKRVHFHGFMLDVHQRIHRLKQSLPKRKPGFMAKSYDPIAPVAEEISEEACLLCFDEFQVTDIADAMILKQLFENLFQNGVVVVATSNRPPEDLYKNGLQRANFVPFIAVLKKYCSTVQLDSGIDYRKRVLPAAGKLYYLTSEADVEAVMDKLFDELAQKQNDLTRPRILKVQGRELRLNKACGTIADFTFEELCDRPLGASDYLEISKHFDTVFVRDIPPLTMAKRTQARRFITLIDTFYEHKVRIICSAATPLQSLFVVEAGSIELEDSRVLMDDLDLSQDSAKGLSMFTGEEEIFAFQRTISRLTEMQTEQYWKDGDRNKEQL", "length": 575, "header": "tr|A0A8V0YNR8-1|A0A8V0YNR8_CHICK Isoform 1 of AFG1 like ATPase OS=Gallus gallus OX=9031 GN=AFG1L PE=3 SV=1 CANONICAL=A0A8V0YNR8-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YHF5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNR8/entry#A0A8V0YHF5-1", "sequence": { "sequence": "MILAHFATAYASQAADEKVVLGTLTDANSRALLVCDGPLEHYDFLIKQEELRNDEQQRRVVQHLQKLHESLKGYSISSQNFLSKLFAKNKPPKGLYVYGDVGTGKTMVMDMFYSHLKVERKKRVHFHGFMLDVHQRIHRLKQSLPKRKPGFMAKSYDPIAPVAEEISEEACLLCFDEFQVTDIADAMILKQLFENLFQNGVVVVATSNRPPEDLYKNGLQRANFVPFIAVLKKYCSTVQLDSGIDYRKRVLPAAGKLYYLTSEADVEAVMDKLFDELAQKQNDLTRPRILKVQGRELRLNKACGTIADFTFEELCDRPLGASDYLEISKHFDTVFVRDIPPLTMAKRTQARRFITLIDTFYEHKVRIICSAATPLQSLFVVEAGSIELEDSRVLMDDLDLSQDSAKGLSMFTGEEEIFAFQRTISRLTEMQTEQYWKDGDRNKEQL", "length": 446, "header": "tr|A0A8V0YHF5-1|A0A8V0YNR8_CHICK Computationally mapped isoform of AFG1 like ATPase OS=Gallus gallus OX=9031 GN=AFG1L PE=3 SV=1 CANONICAL=A0A8V0YNR8-1" }, "locus": { "chromosome": "3", "start_pos": 67145313, "end_pos": 67090748, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034549.1", "url": "https://www.ensembl.org/id/ENSGALT00010034549.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020290.1", "url": "https://www.ensembl.org/id/ENSGALP00010020290.1" } ] } }, { "isoform_ac": "A0A8V0YHG0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNR8/entry#A0A8V0YHG0-1", "sequence": { "sequence": "MVGLLAPDCQCPFTGIYICLFVHCIVPFCQVVWQTEAGGCSGATRPLRCTLRHHSRCQSQRPHPGTPFPSSPRALRRGGRAGKMAAPVSPLVTARCLLRASARRVVRLLPARALPRAYASQAADEKVVLGTLTDANSRALLVCDGPLEHYDFLIKQEELRNDEQQRRVVQHLQKLHESLKGYSISSQNFLSKLFAKNKPPKGLYVYGDVGTGKTMVMDMFYSHLKVERKKRVHFHGFMLDVHQRIHRLKQSLPKRKPGFMAKSYDPIAPVAEEISEEACLLCFDEFQVTDIADAMILKQLFENLFQNGVVVVATSNRPPEDLYKNGLQRANFVPFIAVLKKYCSTVQLDSGIDYRKRVLPAAGKLYYLTSEADVEAVMDKLFDELAQKQNDLTRPRILKVQGRELRLNKACGTIADFTFEELCDRPLGASDYLEISKHFDTVFVRDIPPLTMAKRTQARRFITLIDTFYEHKVRIICSAATPLQSLFVVEAGSIELEDSRVLMDDLDLSQDSAKGLSMFTGEEEIFAFQRTISRLTEMQTEQYWKDGDRNKEQL", "length": 554, "header": "tr|A0A8V0YHG0-1|A0A8V0YNR8_CHICK Computationally mapped isoform of AFG1 like ATPase OS=Gallus gallus OX=9031 GN=AFG1L PE=3 SV=1 CANONICAL=A0A8V0YNR8-1" }, "locus": { "chromosome": "3", "start_pos": 67151547, "end_pos": 67090748, "strand": "+", "evidence": [ { "database": "Ensembl 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{ "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": 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"table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YNX3-1", "uniprot_ac": "A0A8V0YNX3", "uniprot_id": "A0A8V0YNX3_CHICK", "mass": { "chemical_mass": 27607.0, "monoisotopic_mass": 27607.0 }, "refseq": {}, "gene_names": [ { "name": "YIPF6", "type": "recommended", "evidence": [ { "id": "A0A8V0YNX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNX3" } ] } ], "protein_names": [ { "name": "Protein YIPF", "type": "recommended", "evidence": [ { "id": "A0A8V0YNX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNX3/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": 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"UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHI9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHI9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YNX3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNX3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YNX3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNX3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTQSRRHVGSAAKMAAAEGSGAAAAAAEPLFAGLADVSISEDIPVEGEITVPVGSHSPEEDYSTLDEPVRDTIVSLRSLPLSVLRDLKAVGKKFVHVMYPKKSSALLRDWDLWGPLVLCVSLALMLQGGSADSKEDGGPQFAEVFVIIWFGAVVITLNSKLLGGTISFFQSLCVLGYCVLPLTVAMLVCRLVLLAGSGTVSFIIRLIVVIAMFAWSTLASTAFLADSQPPHRKALVVYPIFLFYFVISWMILTFTPQ", "length": 257, "header": "tr|A0A8V0YNX3-1|A0A8V0YNX3_CHICK Isoform 1 of Protein YIPF OS=Gallus gallus OX=9031 GN=YIPF6 PE=3 SV=1 CANONICAL=A0A8V0YNX3-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YHI9-1", "url": 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reticulum to Golgi vesicle-mediated transport", "id": "GO:0006888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006888", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNX3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNX3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNX3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNX3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YNX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNX3" }, { "id": "PF04893", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04893" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Yip1", "eco_id": "ECO_0000259", "start_pos": 99, "end_pos": 250, "start_aa": "Tyr", "end_aa": "Met", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YNZ6-1", "uniprot_ac": "A0A8V0YNZ6", "uniprot_id": "A0A8V0YNZ6_CHICK", "mass": { "chemical_mass": 108671.0, "monoisotopic_mass": 108671.0 }, "refseq": {}, "gene_names": [ { "name": "FAM65C", "type": "recommended", "evidence": [ { "id": "A0A8V0YNZ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNZ6" } ] } ], "protein_names": [ { "name": "RIPOR family member 3", "type": "synonym", "evidence": [ { "id": "A0A8V0YNZ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNZ6/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNZ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNZ6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "FAM65C", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNZ6", "locus": {} } ], "crossref": [ { "id": "A0A8V0YNZ6", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YNZ6", "database": "AlphaFoldDB", "categories": [] }, { "id": "428169", "url": "https://www.ncbi.nlm.nih.gov/gene/428169", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR026136", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026136", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR031780", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031780", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:428169", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:428169", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "ELDYLCG", "url": "https://omabrowser.org/oma/group/ELDYLCG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YHJ8", "url": "https://www.orthodb.org/?gene=A0A8V0YHJ8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YHK5", "url": "https://www.orthodb.org/?gene=A0A8V0YHK5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YHL5", "url": "https://www.orthodb.org/?gene=A0A8V0YHL5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YNW9", "url": "https://www.orthodb.org/?gene=A0A8V0YNW9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YNZ6", "url": "https://www.orthodb.org/?gene=A0A8V0YNZ6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YQN1", "url": "https://www.orthodb.org/?gene=A0A8V0YQN1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YVR5", "url": "https://www.orthodb.org/?gene=A0A8V0YVR5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YVT2", "url": "https://www.orthodb.org/?gene=A0A8V0YVT2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15829", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15829", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15829:SF15", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15829:SF15", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15903", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15903", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YHJ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHJ8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHJ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHJ8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHK5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHK5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHK5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHK5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHL5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHL5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHL5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHL5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YNW9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNW9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YNW9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNW9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YNZ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNZ6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YNZ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNZ6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQN1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQN1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQN1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQN1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YVR5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YVR5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YVR5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YVR5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YVT2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YVT2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YVT2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YVT2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSVKLTFVSSGDGGGISRSCSFTGFSTVQSRKLAKSLGRSSVRSRMSLKSPKAYSSLQKGAVIWDPKPLQVKKIFEALKKGLNEYLEAHQTELDYLSDRHKDTKRNSRLAFYYDLDKQIRSVERYIRKLEFHISKVEELYEAYCIQCRLRDGAANMKHAFSLSPSTKASRESLVELYKNFQECTEDMCFIEGALEVHLGEFHLKMKGLVGFARLCPGDQYEVFVRLGRQKWKLKGKIETDDSQTWDEEEKIFIPNLHEQFEIKVTELRGLATVLVGVVTCDSINFFTTKPQAIIVDITELGTIKLQLEVLWNPFDAENLFLSPGTTAKFSVGSRKSSLYNWTPPNTPSFREKYYPSALQQRQNQGDVSGEAQPPSILSYLAACDFGVHERSKPHSPAETSEGDSFSNEDQRGTESRITAPVLDHRTLPLVIIQETCAEEQHPLPNHATLDILKTPCVDTFPSNPSNFLSHGKGGRHLNQTRNHHLTEQESISQKSLNAANGIKLDGCTKSIDKTLQEVLNLLKFHGVGQAQLEKLEYQVSTLRDKLKLRTLNHKHSSVESLMVETVLESFNFLNADCSADEVSLFGSIRTASISTYNDNMFQSLSCDMKTETSDVTTGDDNLDVLLITHLKLCKALLQKLRLPNVAQIVQENILEEVSEQLQVLGDVLDMSVEEIIQKTKKKKHYLKIWSDVAEPGSILFASAERFRHVLKYTLALKVKEKYPGQLEAVLRKLLEQIVTCDGLLPSPCLQTEPVTLFQFYSYLEKHQITSLEKHIGRLAKEVMLIEELQCPGRLKTLKKLKGKRLNRLQPLPQSLWLLGILQLDDNHRVSKAATSCLSRAAANKNFREKALLFYTDVLVGCDARLQQAACLALKNLRGIESIEQVAHLCQSETEDVRNAARETTLSFGEKGRQAFEKMDRICCELRFINKYGTGVPRLGREINIVQCRFASNSKQAPVALWH", "length": 962, "header": "tr|A0A8V0YNZ6-1|A0A8V0YNZ6_CHICK Isoform 1 of RIPOR family member 3 OS=Gallus gallus OX=9031 GN=FAM65C PE=3 SV=1 CANONICAL=A0A8V0YNZ6-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YHJ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNZ6/entry#A0A8V0YHJ8-1", "sequence": { "sequence": "MSVKLTFVSSGDGGGISRSCSFTGFSTVQSRKLAKSLGRSSVRSRMSLKSPKAYSSLQKGAVIWDPKPLQVKKIFEALKKGLNEYLEAHQTELDYLSDRHKDTKRNSRLLQKQIRSVERYIRKLEFHISKVEELYEAYCIQCRLRDGAANMKHAFSLSPSTKASRESLVELYKNFQECTEDMCFIEGALEVHLGEFHLKMKGLVGFARLCPGDQYEVFVRLGRQKWKLKGKIETDDSQTWDEEEKIFIPNLHEQFEIKVTELRGLATVLVGVVTCDSINFFTTKPQAIIVDITELGTIKLQLEVLWNPFDAENLFLSPGTTAKFSVGSRKSSLYNWTPPNTPSFREKYYPSALQQRQNQGDVSGEAQPPSILSYLAACDFGVHERSKPHSPAETSEGDSFSNEDQRGTESRITAPVLDHRTLPLVIIQETCAEEQHPLPNHATLDILKTPCVDTFPSNPSNFLSHGKGGRHLNQTRNHHLTEQESISQKSLNAANGIKLDGCTKSIDKTLQEVLNLLKFHGVGQAQLEKLEYQVSTLRDKLKLRTLNHKHSSVESLMVETVLESFNFLNADCSADEVSLFGSIRTASISTYNDNMFQSLSCDMKTETSDVTTGDDNLDVLLITHLKLCKALLQKLRLPNVAQIVQENILEEVSEQLQVLGDVLDMSVEEIIQKTKKKKHYLKIWSDVAEPGSILFASAERFRHVLKYTLALKVKEKYPGQLEAVLRKLLEQIVTCDGLLPSPCLQTEPVTLFQFYSYLEKHQITSLEKHIGRLAKEVMLIEELQCPGRLKTLKKLKGKRLNRLQPLPQSLWLLGILQLDDNHRVSKAATSCLSRAAANKNFREKALLFYTDVLVGCDARLQQAACLALKNLRGIESIEQVAHLCQSETEDVRNAARETTLSFGEKGRQAFEKMDRICCELRDAVQQEAEIEITVF", "length": 935, "header": "tr|A0A8V0YHJ8-1|A0A8V0YNZ6_CHICK Computationally mapped isoform of RIPOR family member 3 OS=Gallus gallus OX=9031 GN=FAM65C PE=3 SV=1 CANONICAL=A0A8V0YNZ6-1" }, "locus": { "chromosome": "20", "start_pos": 13876123, "end_pos": 13847868, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034668.1", "url": "https://www.ensembl.org/id/ENSGALT00010034668.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020345.1", "url": "https://www.ensembl.org/id/ENSGALP00010020345.1" } ] } }, { "isoform_ac": "A0A8V0YHK5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNZ6/entry#A0A8V0YHK5-1", "sequence": { "sequence": "MSVKLTFVSSGDGGGISRSCSFTGFSTVQSRKLAKSLGRSSVRSRMSLKSPKAYSSLQKGAVIWDPKPLQVKKIFEALKKGLNEYLEAHQTELDYLSDRHKDTKRNSRLAFYYDLDKQIRSVERYIRKLEFHISKVEELYEAYCIQCRLRDGAANMKHAFSLSPSTKASRESLVELYKNFQECTEDMCFIEGALEVHLGEFHLKMKGLVGFARLCPGDQYEVFVRLGRQKWKLKGKIETDDSQTWDEEEKIFIPNLHEQFEIKVTELRGLATVLVGVVTCDSINFFTTKPQAIIVDITELGTIKLQLEVLWNPFDAENLFLSPGTTAKFSVGSRKSSLYNWTPPNTPSFREKYYPSALQQRQNQGDVSGEAQPPSILSYLAACDFGVHERSKPHSPAETSEGDSFSNEDQRGTESRITAPVLDHRTLPLVIIQETCAEEQHPLPNHATLDILKTPCVDTFPSNPSNFLSHGKGGRHLNQTRNHHLTEQESISQKSLNAANGIKLDGCTKSIDKTLQEVLNLLKFHGVGQAQLEKLEYQVSTLRDKLKLRTLNHKHSSVESLMVETVLESFNFLNADCSADEVSLFGSIRTASISTYNDNMFQSLSCDMKTETSDVTTGDDNLDVLLITHLKLCKALLQKLRLPNVAQIVQENILEEVSEQLQVLGDVLDMSVEEIIQKTKKKKHYLKIWSDVAEPGSILFASAERFRHVLKYTLALKVKEKYPGQLEAVLRKLLEQIVTCDGLLPSPCLQTEPVTLFQFYSYLEKHQITSLEKHIGRLAKEVMLIEELQCPGRLKTLKKLKGKRLNRLQPLPQSLWLLGILQLDDNHRVSKAATSCLSRAAANKNFREKALLFYTDVLVGCDARLQQAACLALKNLRGIESIEQVAHLCQSETEDVRNAARETTLSFGKSSCNLKCRFQKVV", "length": 922, "header": "tr|A0A8V0YHK5-1|A0A8V0YNZ6_CHICK Computationally mapped isoform of RIPOR family member 3 OS=Gallus gallus OX=9031 GN=FAM65C PE=3 SV=1 CANONICAL=A0A8V0YNZ6-1" }, "locus": { "chromosome": "20", "start_pos": 13874930, "end_pos": 13847868, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034690.1", "url": "https://www.ensembl.org/id/ENSGALT00010034690.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020355.1", "url": "https://www.ensembl.org/id/ENSGALP00010020355.1" } ] } }, { "isoform_ac": "A0A8V0YHL5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNZ6/entry#A0A8V0YHL5-1", "sequence": { "sequence": "MSVKLTFVSSGDGGGISRSCSFTGFSTVQSRKLAKSLGRSSVRSRMSLKSPKAYSSLQKGAVIWDPKPLQVKKIFEALKKGLNEYLEAHQTELDYLSDRHKDTKRNSRLAFYYDLDKVRIQIRSVERYIRKLEFHISKVEELYEAYCIQCRLRDGAANMKHAFSLSPSTKASRESLVELYKNFQECTEDMCFIEGALEVHLGEFHLKMKGLVGFARLCPGDQYEVFVRLGRQKWKLKGKIETDDSQTWDEEEKIFIPNLHEQFEIKVTELRGLATVLVGVVTCDSINFFTTKPQAIIVDITELGTIKLQLEVLWNPFDAENLFLSPGTTAKFSVGSRKSSLYNWTPPNTPSFREKYYPSALQQRQNQGDVSGEAQPPSILSYLAACDFGVHERSKPHSPAETSEGDSFSNEDQRGTESRITAPVLDHRTLPLVIIQETCAEEQHPLPNHATLDILKTPCVDTFPSNPSNFLSHGKGGRHLNQTRNHHLTEQESISQKSLNAANGIKLDGCTKSIDKTLQEVLNLLKFHGVGQAQLEKLEYQVSTLRDKLKLRTLNHKHSSVESLMVETVLESFNFLNADCSADEVSLFGSIRTASISTYNDNMFQSLSCDMKTETSDVTTGDDNLDVLLITHLKLCKALLQKLRLPNVAQIVQENILEEVSEQLQVLGDVLDMSVEEIIQKTKKKKHYLKIWSDVAEPGSILFASAERFRHVLKYTLALKVKEKYPGQLEAVLRKLLEQIVTCDGLLPSPCLQTEPVTLFQFYSYLEKHQITSLEKHIGRLAKEVMLIEELQCPGRLKTLKKLKGKRLNRLQPLPQSLWLLGILQLDDNHRVSKAATSCLSRAAANKNFREKALLFYTDVLVGCDARLQQAACLALKNLRGIESIEQVAHLCQSETEDVRNAARETTLSFGEKGRQAFEKMDRICCELRDAVQQEAEIEITVF", "length": 943, "header": "tr|A0A8V0YHL5-1|A0A8V0YNZ6_CHICK Computationally mapped isoform of RIPOR family member 3 OS=Gallus gallus OX=9031 GN=FAM65C PE=3 SV=1 CANONICAL=A0A8V0YNZ6-1" }, "locus": { "chromosome": "20", "start_pos": 13876123, "end_pos": 13847868, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034723.1", "url": "https://www.ensembl.org/id/ENSGALT00010034723.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020365.1", "url": "https://www.ensembl.org/id/ENSGALP00010020365.1" } ] } }, { "isoform_ac": "A0A8V0YNW9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNZ6/entry#A0A8V0YNW9-1", "sequence": { "sequence": "MSVKLTFVSSGDGGGISRSCSFTGFSTVQSRKLAKSLGRSSVRSRMSLKSPKAYSSLQKGAVIWDPKPLQVKKIFEALKKGLNEYLEAHQTELDYLSDRHKDTKRNSRLAFYYDLDKQIRSVERYIRKLEFHISKVEELYEAYCIQCRLRDGAANMKHAFSLSPSTKASRESLVELYKNFQECTEDMCFIEGALEVHLGEFHLKMKGLVGFARLCPGDQYEVFVRLGRQKWKLKGKIETDDSQTWDEEEKIFIPNLHEQFEIKVTELRGLATVLVGVVTCDSINFFTTKPQAIIVDITELGTIKLQLEVLWNRGIGLDDLSRSLPVPDVL", "length": 330, "header": "tr|A0A8V0YNW9-1|A0A8V0YNW9_CHICK Computationally mapped isoform of RIPOR family member 3 OS=Gallus gallus OX=9031 GN=FAM65C PE=3 SV=1 CANONICAL=A0A8V0YNZ6-1" }, "locus": { "chromosome": "20", "start_pos": 13864329, "end_pos": 13847868, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034641.1", "url": "https://www.ensembl.org/id/ENSGALT00010034641.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020331.1", "url": "https://www.ensembl.org/id/ENSGALP00010020331.1" } ] } }, { "isoform_ac": "A0A8V0YNZ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNZ6/entry#A0A8V0YNZ6-1", "sequence": { "sequence": "MSVKLTFVSSGDGGGISRSCSFTGFSTVQSRKLAKSLGRSSVRSRMSLKSPKAYSSLQKGAVIWDPKPLQVKKIFEALKKGLNEYLEAHQTELDYLSDRHKDTKRNSRLAFYYDLDKQIRSVERYIRKLEFHISKVEELYEAYCIQCRLRDGAANMKHAFSLSPSTKASRESLVELYKNFQECTEDMCFIEGALEVHLGEFHLKMKGLVGFARLCPGDQYEVFVRLGRQKWKLKGKIETDDSQTWDEEEKIFIPNLHEQFEIKVTELRGLATVLVGVVTCDSINFFTTKPQAIIVDITELGTIKLQLEVLWNPFDAENLFLSPGTTAKFSVGSRKSSLYNWTPPNTPSFREKYYPSALQQRQNQGDVSGEAQPPSILSYLAACDFGVHERSKPHSPAETSEGDSFSNEDQRGTESRITAPVLDHRTLPLVIIQETCAEEQHPLPNHATLDILKTPCVDTFPSNPSNFLSHGKGGRHLNQTRNHHLTEQESISQKSLNAANGIKLDGCTKSIDKTLQEVLNLLKFHGVGQAQLEKLEYQVSTLRDKLKLRTLNHKHSSVESLMVETVLESFNFLNADCSADEVSLFGSIRTASISTYNDNMFQSLSCDMKTETSDVTTGDDNLDVLLITHLKLCKALLQKLRLPNVAQIVQENILEEVSEQLQVLGDVLDMSVEEIIQKTKKKKHYLKIWSDVAEPGSILFASAERFRHVLKYTLALKVKEKYPGQLEAVLRKLLEQIVTCDGLLPSPCLQTEPVTLFQFYSYLEKHQITSLEKHIGRLAKEVMLIEELQCPGRLKTLKKLKGKRLNRLQPLPQSLWLLGILQLDDNHRVSKAATSCLSRAAANKNFREKALLFYTDVLVGCDARLQQAACLALKNLRGIESIEQVAHLCQSETEDVRNAARETTLSFGEKGRQAFEKMDRICCELRFINKYGTGVPRLGREINIVQCRFASNSKQAPVALWH", "length": 962, "header": "tr|A0A8V0YNZ6-1|A0A8V0YNZ6_CHICK Isoform 1 of RIPOR family member 3 OS=Gallus gallus OX=9031 GN=FAM65C PE=3 SV=1 CANONICAL=A0A8V0YNZ6-1" }, "locus": { "chromosome": "20", "start_pos": 13878033, "end_pos": 13847868, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034708.1", "url": "https://www.ensembl.org/id/ENSGALT00010034708.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020362.1", "url": "https://www.ensembl.org/id/ENSGALP00010020362.1" } ] } }, { "isoform_ac": "A0A8V0YQN1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNZ6/entry#A0A8V0YQN1-1", "sequence": { "sequence": "MSVKLTFVSSGDGGGISRSCSFTGFSTVQSRKLAKSLGRSSVRSRMSLKSPKAYSSLQKGAVIWDPKPLQVKKIFEALKKGLNEYLEAHQTELDYLSDRHKDTKRNSRLAFYYDLDKQIRSVERYIRKLEFHISKVEELYEAYCIQCRLRDGAANMKHAFSLSPSTKASRESLVELYKNFQECTEDMCFIEGALEVHLGEFHLKMKGLVGFARLCPGDQYEVFVRLGRQKWKLKGKIETDDSQTWDEEEKIFIPNLHEQFEIKQVTELRGLATVLVGVVTCDSINFFTTKPQAIIVDITELGTIKLQLEVLWNPFDAENLFLSPGTTAKFSVGSRKSSLYNWTPPNTPSFREKYYPSALQQRQNQGDVSGEAQPPSILSYLAACDFGVHERSKPHSPAETSEGDSFSNEDQRGTESRITAPVLDHRTLPLVIIQETCAEEQHPLPNHATLDILKTPCVDTFPSNPSNFLSHGKGGRHLNQTRNHHLTEQESISQKSLNAANGIKLDGCTKSIDKTLQEVLNLLKFHGVGQAQLEKLEYQVSTLRDKLKLRTLNHKHSSVESLMVETVLESFNFLNADCSADEVSLFGSIRTASISTYNDNMFQSLSCDMKTETSDVTTGDDNLDVLLITHLKLCKALLQKLRLPNVAQIVQENILEEVSEQLQVLGDVLDMSVEEIIQKTKKKKHYLKIWSDVAEPGSILFASAERFRHVLKYTLALKVKEKYPGQLEAVLRKLLEQIVTCDGLLPSPCLQTEPVTLFQFYSYLEKHQITSLEKHIGRLAKEVMLIEELQCPGRLKTLKKLKGKRLNRLQPLPQSLWLLGILQLDDNHRVSKAATSCLSRAAANKNFREKALLFYTDVLVGCDARLQQAACLALKNLRGIESIEQVAHLCQSETEDVRNAARETTLSFGEKGRQAFEKMDRICCELRDAVQQEAEIEITVF", "length": 941, "header": "tr|A0A8V0YQN1-1|A0A8V0YQN1_CHICK Computationally mapped isoform of RIPOR family member 3 OS=Gallus gallus OX=9031 GN=FAM65C PE=3 SV=1 CANONICAL=A0A8V0YNZ6-1" }, "locus": { "chromosome": "20", "start_pos": 13876123, "end_pos": 13847868, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034658.1", "url": "https://www.ensembl.org/id/ENSGALT00010034658.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020337.1", "url": "https://www.ensembl.org/id/ENSGALP00010020337.1" } ] } }, { "isoform_ac": "A0A8V0YVR5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNZ6/entry#A0A8V0YVR5-1", "sequence": { "sequence": "MSVKLTFVSSGDGGGISRSCSFTGFSTVQSRKLAKSLGRSSVRSRMSLKSPKAYSSLQKGAVIWDPKPLQVKKIFEALKKGLNEYLEAHQTELDYLSDRHKDTKRNSRLAFYYDLDKQIRSVERYIRKLEFHISKVEELYEAYCIQCRLRDGAANMKHAFSLSPSTKASRESLVELYKNFQECTEDMCFIEGALEVHLGEFHLKMKVGFARLCPGDQYEVFVRLGRQKWKLKGKIETDDSQTWDEEEKIFIPNLHEQFEIKVTELRGLATVLVGVVTCDSINFFTTKPQAIIVDITELGTIKLQLEVLWNPFDAENLFLSPGTTAKFSVGSRKSSLYNWTPPNTPSFREKYYPSALQQRQNQGDVSGEAQPPSILSYLAACDFGVHERSKPHSPAETSEGDSFSNEDQRGTESRITAPVLDHRTLPLVIIQETCAEEQHPLPNHATLDILKTPCVDTFPSNPSNFLSHGKGGRHLNQTRNHHLTEQESISQKSLNAANGIKLDGCTKSIDKTLQEVLNLLKFHGVGQAQLEKLEYQVSTLRDKLKLRTLNHKHSSVESLMVETVLESFNFLNADCSADEVSLFGSIRTASISTYNDNMFQSLSCDMKTETSDVTTGDDNLDVLLITHLKLCKALLQKLRLPNVAQIVQENILEEVSEQLQVLGDVLDMSVEEIIQKTKKKKHYLKIWSDVAEPGSILFASAERFRHVLKYTLALKVKEKYPGQLEAVLRKLLEQIVTCDGLLPSPCLQTEPVTLFQFYSYLEKHQITSLEKHIGRLAKEVMLIEELQCPGRLKTLKKLKGKRLNRLQPLPQSLWLLGILQLDDNHRVSKAATSCLSRAAANKNFREKALLFYTDVLVGCDARLQQAACLALKNLRGIESIEQVAHLCQSETEDVRNAARETTLSFGEKGRQAFEKMDRICCELRDAVQQEAEIEITVF", "length": 938, "header": "tr|A0A8V0YVR5-1|A0A8V0YVR5_CHICK Computationally mapped isoform of RIPOR family member 3 OS=Gallus gallus OX=9031 GN=FAM65C PE=3 SV=1 CANONICAL=A0A8V0YNZ6-1" }, "locus": { "chromosome": "20", "start_pos": 13876123, "end_pos": 13847868, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034677.1", "url": "https://www.ensembl.org/id/ENSGALT00010034677.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020351.1", "url": "https://www.ensembl.org/id/ENSGALP00010020351.1" } ] } }, { "isoform_ac": "A0A8V0YVT2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNZ6/entry#A0A8V0YVT2-1", "sequence": { "sequence": "MSVKLTFVSSGDGGGISRSCSFTGFSTVQSRKLAKSLGRSSVRSRMSLKSPKAYSSLQKGAVIWDPKPLQVKKIFEALKKGLNEYLEAHQTELDYLSDRHKDTKRNSRLAFYYDLDKQIRSVERYIRKLEFHISKVEELYEAYCIQCRLRDGAANMKHAFSLSPSTKASRESLVELYKNFQECTEDMCFIEGALEVHLGEFHLKMKGLVGFARLCPGDQYEVFVRLGRQKWKLKGKIETDDSQTWDEEEKIFIPNLHEQFEIKVTELRGLATVLVGVVTCDSINFFTTKPQAIIVDITELGTIKLQLEVLWNPFDAENLFLSPGTTAKFSVGSRKSSLYNWTPPNTPSFREKYYPSALQQRQNQGDVSGEAQPPSILSYLAACDFGVHERSKPHSPAETSEGDSFSNEDQRGTESRITAPVLDHRTLPLVIIQETCAEEQHPLPNHATLDILKTPCVDTFPSNPSNFLSHGKGGRHLNQTRNHHLTEQESISQKSLNAANGIKLDGCTKSIDKTLQEVLNLLKFHGVGQAQLEKLEYQVSTLRDKLKLRTLNHKHSSVESLMVETVLESFNFLNADCSADEVSLFGSIRTASISTYNDNMFQSLSCDMKTETSDVTTGDDNLDVLLITHLKLCKALLQKLRLPNVAQIVQENILEEVSEQLQVLGDVLDMSVEEIIQKTKKKKHYLKIWSDVAEPGSILFASAERFRHVLKYTLALKVKEKYPGQLEAVLRKLLEQIVTCDGLLPSPCLQTEPVTLFQFYSYLEKHQITSLEKHIGRLAKEVMLIEELQCPGRLKTLKKLKGKRLNRLQPLPQSLWLLGILQLDDNHRVSKAATSCLSRAAANKNFREKALLFYTDVLVGCDARLQQAACLALKNLRRVLSRLPTCANLKQRM", "length": 893, "header": "tr|A0A8V0YVT2-1|A0A8V0YVT2_CHICK Computationally mapped isoform of RIPOR family member 3 OS=Gallus gallus OX=9031 GN=FAM65C PE=3 SV=1 CANONICAL=A0A8V0YNZ6-1" }, "locus": { "chromosome": "20", "start_pos": 13874850, "end_pos": 13847868, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034734.1", "url": "https://www.ensembl.org/id/ENSGALT00010034734.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020371.1", "url": "https://www.ensembl.org/id/ENSGALP00010020371.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:428169", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:428169", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A061HY09-1", "protein_name": "RIPOR family member 3", "gene_name": "Ripor3", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSVRLRFLSPGDVGAVGTVGRSASFAGFSAQSRRVSKSINRNSVRSRLPAKPSKAYGTLRKGSLCLDPRPQQVKKIFDALKRGLREHLCEQQAELDYLCGRHTDSQRSSRLAFYYDLDKQTRLVERHIRKVEFHISKVDELYEGYCIQWRLRDGASNMQRAFSNGTQSRASRESLQELGRSLQECMEDMCLIEGALEVHLGEFHVKMKGLVGYARLCPGDQYEVLMRLGRQRWRLKGRIEPDDSQTWDEEEKAFVPTVHENLEIKVTELRGLSSMVVGAVTCDIADFFTARPQLVVVDITELGTIKLQLELLWNPLDSECRLVSPSPTGRFSMGSRKGSLYTWTPPSTPSFRDKYYLSVLQQPAQQALLLGGPRATSILGYLSDSELQGPCLRSRSQELLEMDSFSSEDPRDTETSTSASTSDVGFLPMPVGPTASIDKGTREEPPPLGLLPGLAHPAGGVLVEQPGWRDLGGERLALLQDAPIHSPMVPRSQKGQEEEDVGDGVERPVQEVLDLLRSANPTQPQLRELEYQVLGLRDRLKPRGVPPEPMSVQSLMDCILESFAFLNADLASDELSLFGGSQAPERDSPPPPRPSLKVSPSELTAGAPELDMLLTVHLQICKALLQKLASPNLSRMVQDCLLEEAEQQRQVLEVLSDLDFEQVSKARSVEEIIPQAPHRNGGLALWRGCTQPGAVLACSASTLLSQLKRTFLHRVRGKYPGQLEIVCRRLLEQVLNCGGLLATAGLQEEQMVTWFQFHSYLQRQSVSDLEKHLNLLCKEVTLIEELHCAGPAKALRKLHGKRLGQLQPLPQTLQAWALLQLDGSPRVCRAARARLASAARNRRFREKALLYYTNALNDSDATLQQAACMALQQLGGVESVEHIASLCRSDLEAVRVSAREATLSFGEKGRLAFEKMDKLQSEQEIYQEADVEITIF", "length": 936 }, "evidence": [ { "id": "A0A8V0YNZ6", "url": "https://omabrowser.org/oma/group/A0A8V0YNZ6/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A1L3T7-1", "protein_name": "RIPOR family member 3", "gene_name": "Ripor3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSVRLRFLSQGDAGAVGTVGRSASFAGFSSAQSRRLSKSINRNSVRSRLPAKSSKAYRTLRKGSLCLDPRPQQVKKIFDALKRGLREHLCEQQAELDYLCGRHTDTQRGSRLAFYYDLDKQLRLVERHIRKVEFHISKVDELYEAYCIQWRLRDGASNMQRAFSNSTQSRASRESLQELGRSLQECLEDMCLIEGTLEGHLGEFQVKMKGLVGYARLCPGDQYEVLMRLGRQRWRLKGRIEPDDSQTWDEEERVFVPTVHENLEIKVTELRGLSSMVVGAVTCDVADFFMARPQLVVVDITELGTIKLQLELLWNPLDSECRLVSPSPTGRFSMGSRKGSLYTWTPPSTPSFRDKYYLSLLQQPVQQSLLLGGPKATSILGYLSDSELQGPRLRSRSQELLEMDSFSSEDPRDTETSTSASTSDVGFLPVPVGSAACTEEETREGPPPLGLLPGLAHPARGVLVERPGWRDLGGERLALLQDAPIHSPMVPRSRKGQEDGDVGDGVEGPVQEVLDLLRSADPAQPQLRELEYQVLGLRERLKPRGVQPEPVSAQSLMDCILESFAFLNADLASDELSLFGGSQAPERDSPPPPRPSLKVSPSELTAGAPELDTLLTVHLQVCKALLQKLASPNLSRMVEDCLLEEAVQQRQVLEVLSDLDLEQVSKARSVEEIIPQASHRKGGLALWQGCTQPGGVLACPASTLLSQLKKTFLHRVRGKYPGQLEIVCRRLLEQVVGCGGLLVPAGLQEEQVVTWFQFHSYLQRQSISDLEKHLAQLTKEVTLIEELSCAGPAKALRKLHGKCLSQLQPLPQTLQAWALLQLDGPPRLCRAARTRLASAARNKRFREKALLYYTNALNDSDAKVQQAACVALQQLGGIESCEQIVSLCQSDLEAVRVAAREATLSFGEKGRLAFEKMDKLHSEQEAFCQEADVEITIF", "length": 938 }, "evidence": [ { "id": "A0A8V0YNZ6", "url": "https://omabrowser.org/oma/group/A0A8V0YNZ6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3ZX40-1", "protein_name": "RIPOR family member 3", "gene_name": "Ripor3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSVRLRFLSPGEAGAVGTVGRSASFAGFSSAQSRRVSKSINRNSVRSRLPAKSSKAYGTLRKGSLCLDPRPQQVKKIFDALKRGLREHLCEQQAELDYLCRCHTDTQRSSRLAFYYDLDKQMRMVERHIRKVEFHISKVDELYEGYCIQWRLRDGASNMQRAFSNSTQSRASRESLQELGRSLQECLEDMCLIEGTLEGHLGEFHVKMKGLVGYARLCPGDQYEVLMRLGRQRWRLKGRIEPDDSQTWDEEERVFVPTVHENLEIKVTELRGLGSMVVGAVTCDVADFFTARPQLVVVDITELGTIKLQLELLWNPLDSECRLVSPSPTGRFSVGSRKGSLYTWTPPSTPSFRDKYYLSVLQQPMQQALLLGGPRATSILGYLSDSELQGPRLRSRSQELLEMDSFSSEDPRDTETSTSASTSDVGFLPMPVAPTACIEEETREEPPPLGLLPGLTHPAGGVLVEQPGWRDLRGERLDLLLDDPIHSPTVPRSRKGQEDGGAGDGVEGPVQEVLDLLRSADPAQPQLRELEYQVLGLRERLKPRGVQPEPVSAQSLMDCILESFAFLNADLASDELSLFGGSQALERDSPPPPRPSLKVSPSELTAGTPELDTLLTVHLQVCKALLQKLASPNLSRMVQDCLLEEAVQQRQVLEVLSDLDLEQVSKAKSVEEIIPQASQRKGGLALWQGCTQPGGVLACPASTLLSQLKKTFLHRVRGKYPGQLEIVCRRLLEQVLGCGGLFVTAGLQDEQVVTWFQFHSYLQRQNISDLEKHLTQLTKEVTLIEELNCAGPAKALRKLHGKRLSQLQPLPQTLQAWARLQLDGPPRLCRAARMRLASAARNKRFREKALLYYTNALNDSDSKLQQAACMALQQLGGVESIEQIVSLCQSDLEAVRAAAREATLSFGEKGRLAFEKMDKLHAEQEAFCQEADVEITIF", "length": 938 }, "evidence": [ { "id": "A0A8V0YNZ6", "url": "https://omabrowser.org/oma/group/A0A8V0YNZ6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q96MK2-1", "protein_name": "RIPOR family member 3", "gene_name": "RIPOR3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSVRLRFLSPGDTGAVGVVGRSASFAGFSSAQSRRIAKSINRNSVRSRMPAKSSKMYGTLRKGSVCADPKPQQVKKIFEALKRGLKEYLCVQQAELDHLSGRHKDTRRNSRLAFYYDLDKQTRCVERHIRKMEFHISKVDELYEDYCIQCRLRDGASSMQRAFARCPPSRAARESLQELGRSLHECAEDMWLIEGALEVHLGEFHIRMKGLVGYARLCPGDHYEVLMRLGRQRWKLKGRIESDDSQTWDEEEKAFIPTLHENLDIKVTELRGLGSLAVGAVTCDIADFFTTRPQVIVVDITELGTIKLQLEVQWNPFDTESFLVSPSPTGKFSMGSRKGSLYNWTPPSTPSFRERYYLSVLQQPTQQALLLGGPRATSILSYLSDSDLRGPSLRSQSQELPEMDSFSSEDPRDTETSTSASTSDVGFLPLTFGPHASIEEEAREDPLPPGLLPEMAHLSGGPFAEQPGWRNLGGESPSLPQGSLFHSGTASSSQNGHEEGATGDREDGPGVALEGPLQEVLELLRPTDSTQPQLRELEYQVLGFRDRLKPCRARQEHTSAESLMECILESFAFLNADFALDELSLFGGSQGLRKDRPLPPPSSLKASSRELTAGAPELDVLLMVHLQVCKALLQKLASPNLSRLVQECLLEEVAQQKHVLETLSVLDFEKVGKATSIEEIIPQASRTKGCLKLWRGCTGPGRVLSCPATTLLNQLKKTFQHRVRGKYPGQLEIACRRLLEQVVSCGGLLPGAGLPEEQIITWFQFHSYLQRQSVSDLEKHFTQLTKEVTLIEELHCAGQAKVVRKLQGKRLGQLQPLPQTLRAWALLQLDGTPRVCRAASARLAGAVRNRSFREKALLFYTNALAENDARLQQAACLALKHLKGIESIDQTASLCQSDLEAVRAAARETTLSFGEKGRLAFEKMDKLCSEQREVFCQEADVEITIF", "length": 946 }, "evidence": [ { "id": "A0A8V0YNZ6", "url": "https://omabrowser.org/oma/group/A0A8V0YNZ6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 340, "end_pos": 342, "annotation": "n_glycosylation_sequon" }, { "start_pos": 478, "end_pos": 480, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YNZ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNZ6" }, { "id": "PF15903", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15903" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "FAM65 N-terminal", "eco_id": "ECO_0000259", "start_pos": 16, "end_pos": 360, "start_aa": "Ile", "end_aa": "Gln", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 340, "end_pos": 342 }, { "start_pos": 478, "end_pos": 480 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { 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:: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052544.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_046756491", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046756491" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YP11", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP11" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SIMC1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP11", "locus": { "chromosome": "13", "start_pos": 10036182, "end_pos": 10042691, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010014465", "url": "https://www.ensembl.org/id/ENSGALG00010014465" } ] } } ], "crossref": [ { "id": "A0A8V0YP11", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YP11", "database": 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gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YP68", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP68" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "VGLL1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP68", "locus": { "chromosome": "4", "start_pos": 4314012, "end_pos": 4305353, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010014555", "url": "https://www.ensembl.org/id/ENSGALG00010014555" } ] } } ], "crossref": [ { "id": "A0A8V0YP68", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YP68", "database": "AlphaFoldDB", "categories": [] }, { "id": "770844", "url": "https://www.ncbi.nlm.nih.gov/gene/770844", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006627", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006627", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011520", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011520", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:770844", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:770844", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "NDSDMPP", "url": "https://omabrowser.org/oma/group/NDSDMPP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YHT0", "url": "https://www.orthodb.org/?gene=A0A8V0YHT0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YP68", "url": "https://www.orthodb.org/?gene=A0A8V0YP68", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15950", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15950", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15950:SF20", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15950:SF20", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07545", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07545", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YHT0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHT0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHT0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHT0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YP68", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP68", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YP68-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP68-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEETRKLSPKPCKSKEPVKTEWGAQSVVFTYFQGDINSVVDEHFSRALSNARNPQDLSTKHKSEVVVPKHDSMSPHQWNFSSHCSKPYPSSSSTSMSNSALDFPAVAMAGQYQPAALRTHPAQPADLWPFPSLGTPSLTSPVYHHAVPDLHVVDEPISDRKYGSLLGLLQQERCLMSMQECAVKQHSSSTCMTGPARLQNISQSSVPGGERKASSYQGSENPSASHATAEMHAAILQLERGKTFC", "length": 245, "header": "tr|A0A8V0YP68-1|A0A8V0YP68_CHICK Isoform 1 of Vestigial like family member 1 OS=Gallus gallus OX=9031 GN=VGLL1 PE=3 SV=1 CANONICAL=A0A8V0YP68-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YHT0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP68/entry#A0A8V0YHT0-1", "sequence": { "sequence": "MEETRKLSPKPCKSKEPVKTEWGAQSVVFTYFQGDINSVVDEHFSRALSNARNPQDLSTKHKSEVVVPKHDSMSPHQWNFSSHCSKPYPSSSSTSMSNSALDFPAVAMAGQYQPAALRTHPAQPADLWPFPSLGTPSLTSPVYHHAVPDLHVVDEPISDRKYGSLLGLLQQERCLMSMQECAVKQHSSSTCMTGPARLQNISQSSVPGGERKASSYQGSENPSASHATAGIQIHDRRRDLYF", "length": 242, "header": "tr|A0A8V0YHT0-1|A0A8V0YP68_CHICK Computationally mapped isoform of Vestigial like family member 1 OS=Gallus gallus OX=9031 GN=VGLL1 PE=3 SV=1 CANONICAL=A0A8V0YP68-1" }, "locus": { "chromosome": "4", "start_pos": 4310502, "end_pos": 4307318, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034934.1", "url": "https://www.ensembl.org/id/ENSGALT00010034934.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020437.1", "url": "https://www.ensembl.org/id/ENSGALP00010020437.1" } ] } }, { "isoform_ac": "A0A8V0YP68-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP68/entry#A0A8V0YP68-1", "sequence": { "sequence": "MEETRKLSPKPCKSKEPVKTEWGAQSVVFTYFQGDINSVVDEHFSRALSNARNPQDLSTKHKSEVVVPKHDSMSPHQWNFSSHCSKPYPSSSSTSMSNSALDFPAVAMAGQYQPAALRTHPAQPADLWPFPSLGTPSLTSPVYHHAVPDLHVVDEPISDRKYGSLLGLLQQERCLMSMQECAVKQHSSSTCMTGPARLQNISQSSVPGGERKASSYQGSENPSASHATAEMHAAILQLERGKTFC", "length": 245, "header": "tr|A0A8V0YP68-1|A0A8V0YP68_CHICK Isoform 1 of Vestigial like family member 1 OS=Gallus gallus OX=9031 GN=VGLL1 PE=3 SV=1 CANONICAL=A0A8V0YP68-1" }, "locus": { "chromosome": "4", "start_pos": 4309957, "end_pos": 4307318, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034929.1", "url": "https://www.ensembl.org/id/ENSGALT00010034929.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020434.1", "url": "https://www.ensembl.org/id/ENSGALP00010020434.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 135, "start_aa": "Thr", "end_pos": 135, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr135", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:770844", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:770844", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "Q99990-1", "protein_name": "Transcription cofactor vestigial-like protein 1", "gene_name": "VGLL1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEEMKKTAIRLPKGKQKPIKTEWNSRCVLFTYFQGDISSVVDEHFSRALSNIKSPQELTPSSQSEGVMLKNDDSMSPNQWRYSSPWTKPQPEVPVTNRAANCNLHVPGPMAVNQFSPSLARRASVRPGELWHFSSLAGTSSLEPGYSHPFPARHLVPEPQPDGKREPLLSLLQQDRCLARPQESAARENGNPGQIAGSTGLLFNLPPGSVHYKKLYVSRGSASTSLPNETLSELETPGKYSLTPPNHWGHPHRYLQHL", "length": 258 }, "evidence": [ { "id": "A0A8V0YP68", "url": "https://omabrowser.org/oma/group/A0A8V0YP68/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YP68", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP68" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YP68", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP68" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YP68", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP68" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YP68", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP68" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YP68", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP68" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 200, "end_pos": 202, "annotation": "n_glycosylation_sequon" }, { "start_pos": 79, "end_pos": 81, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 135 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 200, "end_pos": 202 }, { "start_pos": 79, "end_pos": 81 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YQJ3-1", "uniprot_ac": "A0A8V0YQJ3", "uniprot_id": "A0A8V0YQJ3_CHICK", "mass": { "chemical_mass": 68895.0, "monoisotopic_mass": 68895.0 }, "refseq": {}, "gene_names": [ { "name": "FAM83F", "type": "recommended", "evidence": [ { "id": "A0A8V0YQJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQJ3" } ] } ], "protein_names": [ { "name": "Family with sequence similarity 83 member F", "type": "synonym", "evidence": [ { "id": "A0A8V0YQJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQJ3/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQJ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQJ3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "FAM83F", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQJ3", "locus": { "chromosome": "1", "start_pos": 50290999, "end_pos": 50323034, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013164", "url": "https://www.ensembl.org/id/ENSGALG00010013164" } ] } } ], "crossref": [ { "id": "A0A8V0YQJ3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YQJ3", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd09186", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09186", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR012461", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012461", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050944", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050944", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YHV4", "url": "https://www.orthodb.org/?gene=A0A8V0YHV4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YIQ6", "url": "https://www.orthodb.org/?gene=A0A8V0YIQ6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YQJ3", "url": "https://www.orthodb.org/?gene=A0A8V0YQJ3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16181", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16181", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16181:SF29", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16181:SF29", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07894", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07894", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YHV4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHV4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHV4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHV4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YIQ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIQ6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YIQ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIQ6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQJ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQJ3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQJ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQJ3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MILQQATAAARGWLSPGTAVRDSWPTMLRDHRPHPPMVRAAGRHACEGARMKGTATSPVNQRSVRGRHGAVRLLHLLGRARAGQVRRCRPCLSLLPQPPGTAGAGSMADSQVFLLDELHVNEKVTEAQACFYYSEEQRRALETLVTRGEAAYRETLQKERLQDFLSSQELQALRGSWRAYDDLRETSKVVRGPDGKAISLAYWPELSDTEVPPLDLGWTDKTFYRGISRVALFTHPRKEENVPHLKEVVREMIQQAQKIIAVVMDVFTDQDIFRDIVNAAYKRRIPVYIILDGDGVKLFLEMCRCLDLSDFQIRNIRIRSVTGVGFYMQSGKIRGTLASRFLMVDGEKVATGSYSFTWSSSHIDRNILLVLTGQHVEMFDVEFRELYAISEEVNFFKELGIANSNLHGIGKSGFHSSMVARKNINPKYGLVAGATRGEMLLWASRHRQDNQDNVEREETSESKKRLNQFLNDLITLEQELPEIEPPLENFNKLNRSPQKLLSRLHMELKNKSKSRESIRDVKKEDAQANSKQGKRFASGFFSRKAKRSPGSSIEANSFASEGHSGEDLGNMKLEYERLSTGHASVRSAEGISGNLGPNSTTSDKSKQSTCVLS", "length": 613, "header": "tr|A0A8V0YQJ3-1|A0A8V0YQJ3_CHICK Isoform 1 of Family with sequence similarity 83 member F OS=Gallus gallus OX=9031 GN=FAM83F PE=3 SV=1 CANONICAL=A0A8V0YQJ3-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YHV4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQJ3/entry#A0A8V0YHV4-1", "sequence": { "sequence": "MRSPKCNLSRSMILQQATAAARGWLSPGTAVRDSWPTMLRDHRPHPPMVRAAGRHACEGARMKGTATSPVNQRSVRGRHGAVRLLHLLGRARAGQVRRCRPCLSLLPQPPGTAGAGSMADSQVFLLDELHVNEKVTEAQACFYYSEEQRRALETLVTRGEAAYRETLQKERLQDFLSSQELQALRGSWRAYDDLRETSKVVRGPDGKAISLAYWPELSDTEVPPLDLGWTDKTFYRGISRVALFTHPRKEENVPHLKEVVREMIQQAQKIIAVVMDVFTDQDIFRDIVNAAYKRRIPVYIILDGDGVKLFLEMCRCLDLSDFQIRNIRIRSVTGVGFYMQSGKIRGTLASRFLMVDGEKVATGSYSFTWSSSHIDRNILLVLTGQHVEMFDVEFRELYAISEEVNFFKELGIANSNLHGIGKSGFHSSMVARKNINPKYGLVAGATRGEMLLWASRHRQDNQDNVEREETSESKKRLNQFLNDLITLEQELPEIEPPLENFNKLNRSPQKLLSRLHMELKNKSKSRESIRDVKKEDAQANSKQGKRFASGFFSRKAKRSPGSSIEANSFASEGHSGEDLGNMKLEYERLSTGHASVRSAEGISVCLKEA", "length": 609, "header": "tr|A0A8V0YHV4-1|A0A8V0YQJ3_CHICK Computationally mapped isoform of Family with sequence similarity 83 member F OS=Gallus gallus OX=9031 GN=FAM83F PE=3 SV=1 CANONICAL=A0A8V0YQJ3-1" }, "locus": { "chromosome": "1", "start_pos": 50318543, "end_pos": 50292003, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031568.1", "url": "https://www.ensembl.org/id/ENSGALT00010031568.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018444.1", "url": "https://www.ensembl.org/id/ENSGALP00010018444.1" } ] } }, { "isoform_ac": "A0A8V0YIQ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQJ3/entry#A0A8V0YIQ6-1", "sequence": { "sequence": "MPNHSLPPGTAGAGSMADSQVFLLDELHVNEKVTEAQACFYYSEEQRRALETLVTRGEAAYRETLQKERLQDFLSSQELQALRGSWRAYDDLRETSKVVRGPDGKAISLAYWPELSDTEVPPLDLGWTDKTFYRGISRVALFTHPRKEENVPHLKEVVREMIQQAQKIIAVVMDVFTDQDIFRDIVNAAYKRRIPVYIILDGDGVKLFLEMCRCLDLSDFQIRNIRIRSVTGVGFYMQSGKIRGTLASRFLMVDGEKVATGSYSFTWSSSHIDRNILLVLTGQHVEMFDVEFRELYAISEEVNFFKELGIANSNLHGIGKSGFHSSMVARKNINPKYGLVAGATRGEMLLWASRHRQDNQDNVEREETSESKKRLNQFLNDLITLEQELPEIEPPLENFNKLNRSPQKLLSRLHMELKNKSKSRESIRDVKKEDAQANSKQGKRFASGFFSRKAKRSPGSSIEANSFASEGHSGEDLGNMKLEYERLSTGHASVRSAEGISGNLGPNSTTSDKSKQSTCVLS", "length": 522, "header": "tr|A0A8V0YIQ6-1|A0A8V0YQJ3_CHICK Computationally mapped isoform of Family with sequence similarity 83 member F OS=Gallus gallus OX=9031 GN=FAM83F PE=3 SV=1 CANONICAL=A0A8V0YQJ3-1" }, "locus": { "chromosome": "1", "start_pos": 50323009, "end_pos": 50301122, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031566.1", "url": "https://www.ensembl.org/id/ENSGALT00010031566.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018442.1", "url": "https://www.ensembl.org/id/ENSGALP00010018442.1" } ] } }, { "isoform_ac": "A0A8V0YQJ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQJ3/entry#A0A8V0YQJ3-1", "sequence": { "sequence": "MILQQATAAARGWLSPGTAVRDSWPTMLRDHRPHPPMVRAAGRHACEGARMKGTATSPVNQRSVRGRHGAVRLLHLLGRARAGQVRRCRPCLSLLPQPPGTAGAGSMADSQVFLLDELHVNEKVTEAQACFYYSEEQRRALETLVTRGEAAYRETLQKERLQDFLSSQELQALRGSWRAYDDLRETSKVVRGPDGKAISLAYWPELSDTEVPPLDLGWTDKTFYRGISRVALFTHPRKEENVPHLKEVVREMIQQAQKIIAVVMDVFTDQDIFRDIVNAAYKRRIPVYIILDGDGVKLFLEMCRCLDLSDFQIRNIRIRSVTGVGFYMQSGKIRGTLASRFLMVDGEKVATGSYSFTWSSSHIDRNILLVLTGQHVEMFDVEFRELYAISEEVNFFKELGIANSNLHGIGKSGFHSSMVARKNINPKYGLVAGATRGEMLLWASRHRQDNQDNVEREETSESKKRLNQFLNDLITLEQELPEIEPPLENFNKLNRSPQKLLSRLHMELKNKSKSRESIRDVKKEDAQANSKQGKRFASGFFSRKAKRSPGSSIEANSFASEGHSGEDLGNMKLEYERLSTGHASVRSAEGISGNLGPNSTTSDKSKQSTCVLS", "length": 613, "header": "tr|A0A8V0YQJ3-1|A0A8V0YQJ3_CHICK Isoform 1 of Family with sequence similarity 83 member F OS=Gallus gallus OX=9031 GN=FAM83F PE=3 SV=1 CANONICAL=A0A8V0YQJ3-1" }, "locus": { "chromosome": "1", "start_pos": 50318510, "end_pos": 50301122, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031565.1", "url": "https://www.ensembl.org/id/ENSGALT00010031565.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018441.1", "url": "https://www.ensembl.org/id/ENSGALP00010018441.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQJ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQJ3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "protein kinase binding", "id": "GO:0019901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019901", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQJ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQJ3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 494, "end_pos": 496, "annotation": "n_glycosylation_sequon" }, { "start_pos": 510, "end_pos": 512, "annotation": "n_glycosylation_sequon" }, { "start_pos": 598, "end_pos": 600, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YQJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQJ3" }, { "id": "PF07894", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07894" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Scaffolding anchor of CK1", "eco_id": "ECO_0000259", "start_pos": 121, "end_pos": 391, "start_aa": "Asn", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 494, "end_pos": 496 }, { "start_pos": 510, "end_pos": 512 }, { "start_pos": 598, "end_pos": 600 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": 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"total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YQK3-1", "uniprot_ac": "A0A8V0YQK3", "uniprot_id": "A0A8V0YQK3_CHICK", "mass": { "chemical_mass": 45161.0, "monoisotopic_mass": 45161.0 }, "refseq": {}, "gene_names": [ { "name": "NUDC", "type": "recommended", "evidence": [ { "id": "A0A8V0YQK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQK3" } ] } ], "protein_names": [ { "name": "Nuclear migration protein nudC", "type": "recommended", "evidence": [ { "id": "A0A8V0YQK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQK3/entry#names_and_taxonomy" } ] }, { "name": "Nuclear distribution protein C homolog", "type": "synonym", "evidence": [ { "id": "A0A8V0YQK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQK3/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Plays a role in neurogenesis and neuronal migration. Necessary for correct formation of mitotic spindles and chromosome separation during mitosis. Necessary for cytokinesis and cell proliferation.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCC2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCC2#function" }, { "database": "UniProtKB", "id": "ARBA00046142", "url": "https://www.uniprot.org/uniprotkb/ARBA00046142#function" }, { "database": "UniProtKB", "id": "A0A8V0YHW0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHW0#function" }, { "database": "UniProtKB", "id": "A0A8V0YHW6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHW6#function" }, { "database": "UniProtKB", "id": "A0A8V0YIR1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIR1#function" }, { "database": "UniProtKB", "id": "A0A8V0YIR6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIR6#function" }, { "database": "UniProtKB", "id": "A0A8V0YKQ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKQ5#function" }, { "database": "UniProtKB", "id": "A0A8V0YQJ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQJ8#function" }, { "database": "UniProtKB", "id": "A0A8V0YQK3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQK3#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQK3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQK3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "NUDC", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQK3", "locus": { "chromosome": "23", "start_pos": 2195614, "end_pos": 2181357, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013165", "url": "https://www.ensembl.org/id/ENSGALG00010013165" } ] } } ], "crossref": [ { "id": "A0A8V0YQK3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YQK3", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd06492", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06492", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "419578", "url": "https://www.ncbi.nlm.nih.gov/gene/419578", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR007052", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007052", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008978", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008978", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032572", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032572", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037898", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037898", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YCC2", "url": "https://www.orthodb.org/?gene=A0A8V0YCC2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YHW0", "url": "https://www.orthodb.org/?gene=A0A8V0YHW0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YHW6", "url": "https://www.orthodb.org/?gene=A0A8V0YHW6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YIR1", "url": "https://www.orthodb.org/?gene=A0A8V0YIR1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YIR6", "url": "https://www.orthodb.org/?gene=A0A8V0YIR6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YKQ5", "url": "https://www.orthodb.org/?gene=A0A8V0YKQ5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YQJ8", "url": "https://www.orthodb.org/?gene=A0A8V0YQJ8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YQK3", "url": "https://www.orthodb.org/?gene=A0A8V0YQK3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12356", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12356", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12356:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12356:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04969", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04969", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16273", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16273", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-141430", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-141430", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-141444", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-141444", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-2467813", "url": 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[ "Protein" ] }, { "id": "A0A8V0YHW0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHW0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHW0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHW0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHW6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHW6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHW6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHW6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YIR1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIR1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YIR1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIR1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YIR6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIR6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YIR6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIR6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YKQ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKQ5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YKQ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKQ5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQJ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQJ8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQJ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQJ8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQK3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQK3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQK3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQK3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGCVHSGSCLLLWPSRRIFSSMLGAGVSITSNVTISWTSPRRKRGTQQLSSSRSWSPRGSRWKEGRFFMKLMVFTNTSEAAWQLVNTFFSFLRRKTDFFTGGEDGVAEKLITDSFNHHNKLAQKERKEKKARQEAERREKAERAAKLAKEAKQEANEPRIKELTDEEAERLQLEIDQKKEAQKEVNNVPVKSSEDDGDSSDSNKQETDDEEKDENDKGKLKPNAGNGADLPNYRWTQTLSELDLAIPFKVTFRLKGKDVVVDIQRRRLRVGLKGHPPVIDGELFNEVKVEESSWLIEDGKTVTVHLEKINKMEWWNKLVSTDPEINTKKINPENSKLSDLDSETRSMVEKMMYDQRQKSMGLPTSDEQKKQDILKKFMEQHPEMDFSKAKFN", "length": 392, "header": "tr|A0A8V0YQK3-1|A0A8V0YQK3_CHICK Isoform 1 of Nuclear migration protein nudC OS=Gallus gallus OX=9031 GN=NUDC PE=3 SV=1 CANONICAL=A0A8V0YQK3-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YCC2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQK3/entry#A0A8V0YCC2-1", "sequence": { "sequence": "SGLIVLFFFSHPSPVPLPCSLYQLVNTFFSFLRRKTDFFTGGEDGVAEKLITDSFNHHNKLAQKERKEKKARQEAERREKAERAAKLAKEAKQEANEPRIKELTDEEAERLQLEIDQKKEAQKEVNNVPVKSSEDDGDSSDSNKQETDDEEKDENDKGKLKPNAGNGADLPNYRWTQTLSELDLAIPFKVTFRLKGKDVVVDIQRRRLRVGLKGHPPVIDGELFNEVKVEESSWLIEDGKTVTVHLEKINKMEWWNKLVSTDPEINTKKINPENSKLSDLDSETRSMVEKMMYDQRQKSMGLPTSDEQKKQDILKKFMEQHPEMDFSKAKFN", "length": 332, "header": "tr|A0A8V0YCC2-1|A0A8V0YCC2_CHICK Computationally mapped isoform of Nuclear migration protein nudC OS=Gallus gallus OX=9031 GN=NUDC PE=3 SV=1 CANONICAL=A0A8V0YQK3-1" }, "locus": { "chromosome": "23", "start_pos": 2194541, "end_pos": 2187890, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031569.1", "url": "https://www.ensembl.org/id/ENSGALT00010031569.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018445.1", "url": "https://www.ensembl.org/id/ENSGALP00010018445.1" } ] } }, { "isoform_ac": "A0A8V0YHW0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQK3/entry#A0A8V0YHW0-1", "sequence": { "sequence": "KTKPEAAPHGLQEKCWLVNTFFSFLRRKTDFFTGGEDGVAEKLITDSFNHHNKLAQKERKEKKARQEAERREKAERAAKLAKEAKQEANEPRIKELTDEEAERLQLEIDQKKEAQKEVNNVPVKSSEDDGDSSDSNKQETDDEEKDENDKGKLKPNAGNGADLPNYRWTQTLSELDLAIPFKVTFRLKGKDVVVDIQRRRLRVGLKGHPPVIDGELFNEVKVEESSWLIEDGKTVTVHLEKINKMEWWNKLVSTDPEINTKKINPENSKLSDLDSETRSMVEKMMYDQRQKSMGLPTSDEQKKQDILKKFMEQHPEMDFSKAKFN", "length": 325, "header": "tr|A0A8V0YHW0-1|A0A8V0YQK3_CHICK Computationally mapped isoform of Nuclear migration protein nudC OS=Gallus gallus OX=9031 GN=NUDC PE=3 SV=1 CANONICAL=A0A8V0YQK3-1" }, "locus": { "chromosome": "23", "start_pos": 2194541, "end_pos": 2185897, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031578.1", "url": "https://www.ensembl.org/id/ENSGALT00010031578.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018449.1", "url": "https://www.ensembl.org/id/ENSGALP00010018449.1" } ] } }, { "isoform_ac": "A0A8V0YHW6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQK3/entry#A0A8V0YHW6-1", "sequence": { "sequence": "MGPCAQRSHLGGPDVPVPGLRRTLRTRQRPGNEVPPGPTQRLPEYMRTKRRARPGRTATGQQQLVNTFFSFLRRKTDFFTGGEDGVAEKLITDSFNHHNKLAQKERKEKKARQEAERREKAERAAKLAKEAKQEANEPRIKELTDEEAERLQLEIDQKKEAQKEVNNVPVKSSEDDGDSSDSNKQETDDEEKDENDKGKLKPNAGNGADLPNYRWTQTLSELDLAIPFKVTFRLKGKDVVVDIQRRRLRVGLKGHPPVIDGELFNEVKVEESSWLIEDGKTVTVHLEKINKMEWWNKLVSTDPEINTKKINPENSKLSDLDSETRSMVEKMMYDQRQKSMGLPTSDEQKKQDILKKFMEQHPEMDFSKAKFN", "length": 372, "header": "tr|A0A8V0YHW6-1|A0A8V0YQK3_CHICK Computationally mapped isoform of Nuclear migration protein nudC OS=Gallus gallus OX=9031 GN=NUDC PE=3 SV=1 CANONICAL=A0A8V0YQK3-1" }, "locus": { "chromosome": "23", "start_pos": 2194541, "end_pos": 2181365, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031584.1", "url": "https://www.ensembl.org/id/ENSGALT00010031584.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018454.1", "url": "https://www.ensembl.org/id/ENSGALP00010018454.1" } ] } }, { "isoform_ac": "A0A8V0YIR1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQK3/entry#A0A8V0YIR1-1", "sequence": { "sequence": "DGVERGGSGGAGGSLRWHPPGHGPAAPRRRLVNTFFSFLRRKTDFFTGGEDGVAEKLITDSFNHHNKLAQKERKEKKARQEAERREKAERAAKLAKEAKQEANEPRIKELTDEEAERLQLEIDQKKEAQKEVNNVPVKSSEDDGDSSDSNKQETDDEEKDENDKGKLKPNAGNGADLPNYRWTQTLSELDLAIPFKVTFRLKGKDVVVDIQRRRLRVGLKGHPPVIDGELFNEVKVEESSWLIEDGKTVTVHLEKINKMEWWNKLVSTDPEINTKKINPENSKLSDLDSETRSMVEKMMYDQRQKSMGLPTSDEQKKQDILKKFMEQHPEMDFSKAKFN", "length": 339, "header": "tr|A0A8V0YIR1-1|A0A8V0YQK3_CHICK Computationally mapped isoform of Nuclear migration protein nudC OS=Gallus gallus OX=9031 GN=NUDC PE=3 SV=1 CANONICAL=A0A8V0YQK3-1" }, "locus": { "chromosome": "23", "start_pos": 2194541, "end_pos": 2186766, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031573.1", "url": "https://www.ensembl.org/id/ENSGALT00010031573.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018447.1", "url": "https://www.ensembl.org/id/ENSGALP00010018447.1" } ] } }, { "isoform_ac": "A0A8V0YIR6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQK3/entry#A0A8V0YIR6-1", "sequence": { "sequence": "MYREAVSPGTSAKRKELVNTFFSFLRRKTDFFTGGEDGVAEKLITDSFNHHNKLAQKERKEKKARQEAERREKAERAAKLAKEAKQEANEPRIKELTDEEAERLQLEIDQKKEAQKEVNNVPVKSSEDDGDSSDSNKQETDDEEKDENDKGKLKPNAGNGADLPNYRWTQTLSELDLAIPFKVTFRLKGKDVVVDIQRRRLRVGLKGHPPVIDGELFNEVKVEESSWLIEDGKTVTVHLEKINKMEWWNKLVSTDPEINTKKINPENSKLSDLDSETRSMVEKMMYDQRQKSMGLPTSDEQKKQDILKKFMEQHPEMDFSKAKFN", "length": 325, "header": "tr|A0A8V0YIR6-1|A0A8V0YQK3_CHICK Computationally mapped isoform of Nuclear migration protein nudC OS=Gallus gallus OX=9031 GN=NUDC PE=3 SV=1 CANONICAL=A0A8V0YQK3-1" }, "locus": { "chromosome": "23", "start_pos": 2194541, "end_pos": 2184252, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031581.1", "url": "https://www.ensembl.org/id/ENSGALT00010031581.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018452.1", "url": "https://www.ensembl.org/id/ENSGALP00010018452.1" } ] } }, { "isoform_ac": "A0A8V0YKQ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQK3/entry#A0A8V0YKQ5-1", "sequence": { "sequence": "MGLSAEEAAEQEDRFDGILLAMAQQHQGGVCELITDSFNHHNKLAQKERKEKKARQEAERREKAERAAKLAKEAKQEANEPRIKELTDEEAERLQLEIDQKKEAQKEVNNVPVKSSEDDGDSSDSNKQETDDEEKDENDKGKLKPNAGNGADLPNYRWTQTLSELDLAIPFKVTFRLKGKDVVVDIQRRRLRVGLKGHPPVIDGELFNEVKVEESSWLIEDGKTVTVHLEKINKMEWWNKLVSTDPEINTKKINPENSKLSDLDSETRSMVEKMMYDQRQKSMGLPTSDEQKKQDILKKFMEQHPEMDFSKAKFN", "length": 315, "header": "tr|A0A8V0YKQ5-1|A0A8V0YQK3_CHICK Computationally mapped isoform of Nuclear migration protein nudC OS=Gallus gallus OX=9031 GN=NUDC PE=3 SV=1 CANONICAL=A0A8V0YQK3-1" }, "locus": { "chromosome": "23", "start_pos": 2194541, "end_pos": 2186767, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031576.1", "url": "https://www.ensembl.org/id/ENSGALT00010031576.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018448.1", "url": "https://www.ensembl.org/id/ENSGALP00010018448.1" } ] } }, { "isoform_ac": "A0A8V0YQJ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQK3/entry#A0A8V0YQJ8-1", "sequence": { "sequence": "MGASSAPQNFGETVLKTSCSILRVQLVNTFFSFLRRKTDFFTGGEDGVAEKLITDSFNHHNKLAQKERKEKKARQEAERREKAERAAKLAKEAKQEANEPRIKELTDEEAERLQLEIDQKKEAQKEVNNVPVKSSEDDGDSSDSNKQETDDEEKDENDKGKLKPNAGNGADLPNYRWTQTLSELDLAIPFKVTFRLKGKDVVVDIQRRRLRVGLKGHPPVIDGELFNEVKVEESSWLIEDGKTVTVHLEKINKMEWWNKLVSTDPEINTKKINPENSKLSDLDSETRSMVEKMMYDQRQKSMGLPTSDEQKKQDILKKFMEQHPEMDFSKAKFN", "length": 334, "header": "tr|A0A8V0YQJ8-1|A0A8V0YQJ8_CHICK Computationally mapped isoform of Nuclear migration protein nudC OS=Gallus gallus OX=9031 GN=NUDC PE=3 SV=1 CANONICAL=A0A8V0YQK3-1" }, "locus": { "chromosome": "23", "start_pos": 2194541, "end_pos": 2187282, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031570.1", "url": "https://www.ensembl.org/id/ENSGALT00010031570.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018446.1", "url": "https://www.ensembl.org/id/ENSGALP00010018446.1" } ] } }, { "isoform_ac": "A0A8V0YQK3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQK3/entry#A0A8V0YQK3-1", "sequence": { "sequence": "MGCVHSGSCLLLWPSRRIFSSMLGAGVSITSNVTISWTSPRRKRGTQQLSSSRSWSPRGSRWKEGRFFMKLMVFTNTSEAAWQLVNTFFSFLRRKTDFFTGGEDGVAEKLITDSFNHHNKLAQKERKEKKARQEAERREKAERAAKLAKEAKQEANEPRIKELTDEEAERLQLEIDQKKEAQKEVNNVPVKSSEDDGDSSDSNKQETDDEEKDENDKGKLKPNAGNGADLPNYRWTQTLSELDLAIPFKVTFRLKGKDVVVDIQRRRLRVGLKGHPPVIDGELFNEVKVEESSWLIEDGKTVTVHLEKINKMEWWNKLVSTDPEINTKKINPENSKLSDLDSETRSMVEKMMYDQRQKSMGLPTSDEQKKQDILKKFMEQHPEMDFSKAKFN", "length": 392, "header": "tr|A0A8V0YQK3-1|A0A8V0YQK3_CHICK Isoform 1 of Nuclear migration protein nudC OS=Gallus gallus OX=9031 GN=NUDC PE=3 SV=1 CANONICAL=A0A8V0YQK3-1" }, "locus": { "chromosome": "23", "start_pos": 2194541, "end_pos": 2184822, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031580.1", "url": "https://www.ensembl.org/id/ENSGALT00010031580.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018451.1", "url": "https://www.ensembl.org/id/ENSGALP00010018451.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-141430", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-141430", "resource": "Reactome", "description": "Inactivation of APC/C via direct inhibition of the APC/C complex" }, { "id": "R-GGA-141444", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-141444", "resource": "Reactome", "description": "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" }, { "id": "R-GGA-2467813", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2467813", "resource": "Reactome", "description": "Separation of Sister Chromatids" }, { "id": "R-GGA-2500257", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2500257", "resource": "Reactome", "description": "Resolution of Sister Chromatid Cohesion" }, { "id": "R-GGA-5663220", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5663220", "resource": "Reactome", "description": "RHO GTPases Activate Formins" }, { "id": "R-GGA-9648025", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9648025", "resource": "Reactome", "description": "EML4 and NUDC in mitotic spindle formation" }, { "id": "R-GGA-9696270", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9696270", "resource": "Reactome", "description": "RND2 GTPase cycle" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQK3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQK3" } ], "pmid": "" }, { "name": "microtubule", "id": "GO:0005874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005874", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQK3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQK3" } ], "pmid": "" }, { "name": "midbody", "id": "GO:0030496", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030496", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQK3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQK3" } ], "pmid": "" }, { "name": "mitotic spindle", "id": "GO:0072686", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072686", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQK3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQK3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQK3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQK3" } ], "pmid": "" }, { "name": "protein folding", "id": "GO:0006457", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006457", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQK3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQK3" } ], "pmid": "" }, { "name": "mitotic metaphase chromosome alignment", "id": "GO:0007080", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007080", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQK3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQK3" } ], "pmid": "" }, { "name": "mitotic spindle organization", "id": "GO:0007052", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007052", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQK3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQK3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "unfolded protein binding", "id": "GO:0051082", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051082", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQK3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQK3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 32, "end_pos": 34, "annotation": "n_glycosylation_sequon" }, { "start_pos": 76, "end_pos": 78, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YQK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQK3" }, { "id": "PS51203", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51203" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CS", "eco_id": "ECO_0000259", "start_pos": 228, "end_pos": 319, "start_aa": "Ala", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 32, "end_pos": 34 }, { "start_pos": 76, "end_pos": 78 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YPT1-1", "uniprot_ac": "A0A8V0YPT1", "uniprot_id": "A0A8V0YPT1_CHICK", "mass": { "chemical_mass": 50057.0, "monoisotopic_mass": 50057.0 }, "refseq": {}, "gene_names": [ { "name": "MFSD9", "type": "recommended", "evidence": [ { "id": "A0A8V0YPT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPT1" } ] } ], "protein_names": [ { "name": "Major facilitator superfamily domain containing 9", "type": "synonym", "evidence": [ { "id": "A0A8V0YPT1", "database": "UniProtKB", "url": 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GN=FHL3 PE=1 SV=1 CANONICAL=A0A8V0YPE1-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YHZ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPE1/entry#A0A8V0YHZ6-1", "sequence": { "sequence": "MSGEGGPQTGTMTECFDCDNCKESLYGRKYIQMDNGPYCIPCYDAHFANTCDECKELIGHDCRELYYEDRHYHEHCFRCFRCDRSLADEPFTCQDEELLCNDCYCNEFSSKCIACEKTVMPGSRKLEYNGQTWHEHCFICSSCQQPIGSRSFIPDKKDYYCVPCYESKFAPRCTRCKKTLTKGGVTYRDEPWHKECFVCTGCMTPLAGQQFTSQDDNPYCIKCFGNLYAKKCSACTKPITGFGGGKYISFEDRHWHHNCFNCARCDTSLVGKGFIPDNDEILCRDCSNDL", "length": 290, "header": "tr|A0A8V0YHZ6-1|A0A8V0YPE1_CHICK Computationally mapped isoform of Four and a half LIM domains protein 3 OS=Gallus gallus OX=9031 GN=FHL3 PE=1 SV=1 CANONICAL=A0A8V0YPE1-1" }, "locus": { "chromosome": "23", "start_pos": 3876557, "end_pos": 3856392, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010035175.1", "url": "https://www.ensembl.org/id/ENSGALT00010035175.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020512.1", "url": "https://www.ensembl.org/id/ENSGALP00010020512.1" } ] } }, { "isoform_ac": "A0A8V0YI01-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPE1/entry#A0A8V0YI01-1", "sequence": { "sequence": "MQGEGGPQTGTMTECFDCDNCKESLYGRKYIQMDNGPYCIPCYDAHFANTCDECKELIGHDCRELYYEDRHYHEHCFRCFRCDRSLADEPFTCQDEELLCNDCYCNEFSSKCIACEKTVMPGSRKLEYNGQTWHEHCFICSSCQQPIGSRSFIPDKKDYYCVPCYESKFAPRCTRCKKTLTKGGVTYRDEPWHKECFVCTGCMTPLAGQQFTSQDDNPYCIKCFGNLYAKKCSACTKPITGFGGGKYISFEDRHWHHNCFNCARCDTSLVGKGFIPDNDEILCRDCSNDL", "length": 290, "header": "tr|A0A8V0YI01-1|A0A8V0YPE1_CHICK Computationally mapped isoform of Four and a half LIM domains protein 3 OS=Gallus gallus OX=9031 GN=FHL3 PE=1 SV=1 CANONICAL=A0A8V0YPE1-1" }, "locus": { "chromosome": "23", "start_pos": 3876557, "end_pos": 3864330, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010035191.1", "url": "https://www.ensembl.org/id/ENSGALT00010035191.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020517.1", "url": "https://www.ensembl.org/id/ENSGALP00010020517.1" } ] } }, { "isoform_ac": "A0A8V0YPB0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPE1/entry#A0A8V0YPB0-1", "sequence": { "sequence": "MVAVLAAGEGGPQTGTMTECFDCDNCKESLYGRKYIQMDNGPYCIPCYDAHFANTCDECKELIGHDCRELYYEDRHYHEHCFRCFRCDRSLADEPFTCQDEELLCNDCYCNEFSSKCIACEKTVMPGSRKLEYNGQTWHEHCFICSSCQQPIGSRSFIPDKKDYYCVPCYESKFAPRCTRCKKTLTKGGVTYRDEPWHKECFVCTGCMTPLAGQQFTSQDDNPYCIKCFGNLYAKKCSACTKPITGFGGGKYISFEDRHWHHNCFNCARCDTSLVGKGFIPDNDEILCRDCSNDL", "length": 295, "header": "tr|A0A8V0YPB0-1|A0A8V0YPB0_CHICK Computationally mapped isoform of Four and a half LIM domains protein 3 OS=Gallus gallus OX=9031 GN=FHL3 PE=1 SV=1 CANONICAL=A0A8V0YPE1-1" }, "locus": { "chromosome": "23", "start_pos": 3876557, "end_pos": 3874206, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010035165.1", "url": "https://www.ensembl.org/id/ENSGALT00010035165.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020506.1", "url": "https://www.ensembl.org/id/ENSGALP00010020506.1" } ] } }, { "isoform_ac": "A0A8V0YPE1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPE1/entry#A0A8V0YPE1-1", "sequence": { "sequence": "MDFLLFHLLSAQPVKAIAARQPVDQKSGVLQRAGEGGPQTGTMTECFDCDNCKESLYGRKYIQMDNGPYCIPCYDAHFANTCDECKELIGHDCRELYYEDRHYHEHCFRCFRCDRSLADEPFTCQDEELLCNDCYCNEFSSKCIACEKTVMPGSRKLEYNGQTWHEHCFICSSCQQPIGSRSFIPDKKDYYCVPCYESKFAPRCTRCKKTLTKGGVTYRDEPWHKECFVCTGCMTPLAGQQFTSQDDNPYCIKCFGNLYAKKCSACTKPITGFGGGKYISFEDRHWHHNCFNCARCDTSLVGKGFIPDNDEILCRDCSNDL", "length": 321, "header": "tr|A0A8V0YPE1-1|A0A8V0YPE1_CHICK Isoform 1 of Four and a half LIM domains protein 3 OS=Gallus gallus OX=9031 GN=FHL3 PE=1 SV=1 CANONICAL=A0A8V0YPE1-1" }, "locus": { "chromosome": "23", "start_pos": 3876557, "end_pos": 3856605, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010035182.1", "url": "https://www.ensembl.org/id/ENSGALT00010035182.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020514.1", "url": "https://www.ensembl.org/id/ENSGALP00010020514.1" } ] } }, { "isoform_ac": "A0A8V0YW64-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPE1/entry#A0A8V0YW64-1", "sequence": { "sequence": "MTECFDCDNCKESLYGRKYIQMDNGPYCIPCYDAHFANTCDECKELIGHDCRELYYEDRHYHEHCFRCFRCDRSLADEPFTCQDEELLCNDCYCNEFSSKCIACEKTVMPGSRKLEYNGQTWHEHCFICSSCQQPIGSRSFIPDKKDYYCVPCYESKFAPRCTRCKKPPWLASSSPPRMTTPTASSALGTSMPRSAVHAQSPSQASVVVNISPLRIVTGTITALTVLAVTPLWSGKALSLTMMRSCAVTAATTYEPWRTPWGRGFLYSSESLCQLPLTALQRQGT", "length": 285, "header": "tr|A0A8V0YW64-1|A0A8V0YW64_CHICK Computationally mapped isoform of Four and a half LIM domains 3 OS=Gallus gallus OX=9031 GN=FHL3 PE=1 SV=1 CANONICAL=A0A8V0YPE1-1" }, "locus": { "chromosome": "23", "start_pos": 3876651, "end_pos": 3874629, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010035202.1", "url": "https://www.ensembl.org/id/ENSGALT00010035202.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020523.1", "url": "https://www.ensembl.org/id/ENSGALP00010020523.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPE1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPE1" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPE1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPE1" } ], "pmid": "" }, { "name": "stress fiber", "id": "GO:0001725", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001725", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPE1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPE1" } ], "pmid": "" }, { "name": "Z disc", "id": "GO:0030018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030018", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPE1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPE1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPE1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPE1" } ], "pmid": "" }, { "name": "actin cytoskeleton organization", "id": "GO:0030036", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030036", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPE1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPE1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPE1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPE1" } ], "pmid": "" }, { "name": "actin binding", "id": "GO:0003779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003779", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPE1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPE1" } ], "pmid": "" }, { "name": "transcription coregulator activity", "id": "GO:0003712", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003712", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPE1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPE1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YPE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPE1" }, { "id": "PS50023", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50023" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "LIM zinc-binding", "eco_id": "ECO_0000259", "start_pos": 80, "end_pos": 140, "start_aa": "Asn", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YR84-1", "uniprot_ac": "A0A8V0YR84", "uniprot_id": "A0A8V0YR84_CHICK", "mass": { "chemical_mass": 27303.0, "monoisotopic_mass": 27303.0 }, "refseq": {}, "gene_names": [ { "name": "UBE2V1", "type": "recommended", "evidence": [ { "id": "A0A8V0YR84", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YR84" } ] } ], "protein_names": [ { "name": "Ubiquitin conjugating enzyme E2 V1", "type": "synonym", "evidence": [ { "id": "A0A8V0YR84", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YR84/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YR84", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YR84" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "UBE2V1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YR84", "locus": { "chromosome": "20", "start_pos": 14095549, "end_pos": 14080849, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010014676", "url": "https://www.ensembl.org/id/ENSGALG00010014676" } ] } } ], "crossref": [ { "id": "A0A8V0YR84", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YR84", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd23807", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd23807", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100538349", "url": "https://www.ncbi.nlm.nih.gov/gene/100538349", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000608", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000608", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016135", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016135", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "GPESCSY", "url": "https://omabrowser.org/oma/group/GPESCSY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YI20", "url": "https://www.orthodb.org/?gene=A0A8V0YI20", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YPE9", "url": "https://www.orthodb.org/?gene=A0A8V0YPE9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YR79", "url": "https://www.orthodb.org/?gene=A0A8V0YR79", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YR84", "url": "https://www.orthodb.org/?gene=A0A8V0YR84", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YW76", "url": "https://www.orthodb.org/?gene=A0A8V0YW76", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24068", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24068", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00179", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00179", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YI20", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI20", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YI20-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI20-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YPE9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPE9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YPE9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPE9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YR79", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YR79", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YR79-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YR79-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YR84", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YR84", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YR84-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YR84-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YW76", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YW76", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YW76-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YW76-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLESVSVLQASLEELGLCFPRDKAAADLGGAQTARAPPAKQKTQVNSCMPARATKPGRPPACTTKLSSAAASPLARPPAPRGLTSRVALTRRQGVGLRRQRRKMAATTGAGVKVPRNFRLLEELEEGQKGVGDGTVSWGLEDDEDMTLTRWTGMIIGPPRTIYENRIYSLKIECGPKYPEAPPFVRFVTKINMNGVNSSNGVVDPRAISVLAKWQNSFSIKVVLQELRRLMMSKENMKLPQPPEGQCYSN", "length": 250, "header": "tr|A0A8V0YR84-1|A0A8V0YR84_CHICK Isoform 1 of Ubiquitin conjugating enzyme E2 V1 OS=Gallus gallus OX=9031 GN=UBE2V1 PE=4 SV=1 CANONICAL=A0A8V0YR84-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YI20-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YR84/entry#A0A8V0YI20-1", "sequence": { "sequence": "MESFAFVLLPAITTGVKVPRNFRLLEELEEGQKGVGDGTVSWGLEDDEDMTLTRWTGMIIGPPRTIYENRIYSLKIECGPKYPEAPPFVRFVTKINMNGVNSSNGVVDPRAISVLAKWQNSFSIKVVLQELRRLMMSKENMKLPQPPEGQCYSN", "length": 154, "header": "tr|A0A8V0YI20-1|A0A8V0YR84_CHICK Computationally mapped isoform of Ubiquitin conjugating enzyme E2 V1 OS=Gallus gallus OX=9031 GN=UBE2V1 PE=4 SV=1 CANONICAL=A0A8V0YR84-1" }, "locus": { "chromosome": "20", "start_pos": 14093924, "end_pos": 14089842, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010035251.1", "url": "https://www.ensembl.org/id/ENSGALT00010035251.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020538.1", "url": "https://www.ensembl.org/id/ENSGALP00010020538.1" } ] } }, { "isoform_ac": "A0A8V0YPE9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YR84/entry#A0A8V0YPE9-1", "sequence": { "sequence": "MKSHVAWDQGPSPQMQHCDLKVPRNFRLLEELEEGQKGVGDGTVSWGLEDDEDMTLTRWTGMIIGPPRTIYENRIYSLKIECGPKYPEAPPFVRFVTKINMNGVNSSNGVVDPRAISVLAKWQNSFSIKVVLQELRRLMMSKENMKLPQPPEGQCYSN", "length": 158, "header": "tr|A0A8V0YPE9-1|A0A8V0YPE9_CHICK Computationally mapped isoform of Ubiquitin conjugating enzyme E2 V1 OS=Gallus gallus OX=9031 GN=UBE2V1 PE=4 SV=1 CANONICAL=A0A8V0YR84-1" }, "locus": { "chromosome": "20", "start_pos": 14093924, "end_pos": 14089421, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010035266.1", "url": "https://www.ensembl.org/id/ENSGALT00010035266.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020542.1", "url": "https://www.ensembl.org/id/ENSGALP00010020542.1" } ] } }, { "isoform_ac": "A0A8V0YR79-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YR84/entry#A0A8V0YR79-1", "sequence": { "sequence": "MNKELALVVLIRFHSRPEHPSRVKVPRNFRLLEELEEGQKGVGDGTVSWGLEDDEDMTLTRWTGMIIGPPRTIYENRIYSLKIECGPKYPEAPPFVRFVTKINMNGVNSSNGVVDPRAISVLAKWQNSFSIKVVLQELRRLMMSKENMKLPQPPEGQCYSN", "length": 161, "header": "tr|A0A8V0YR79-1|A0A8V0YR79_CHICK Computationally mapped isoform of Ubiquitin conjugating enzyme E2 V1 OS=Gallus gallus OX=9031 GN=UBE2V1 PE=4 SV=1 CANONICAL=A0A8V0YR84-1" }, "locus": { "chromosome": "20", "start_pos": 14093924, "end_pos": 14083540, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010035275.1", "url": "https://www.ensembl.org/id/ENSGALT00010035275.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020546.1", "url": "https://www.ensembl.org/id/ENSGALP00010020546.1" } ] } }, { "isoform_ac": "A0A8V0YR84-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YR84/entry#A0A8V0YR84-1", "sequence": { "sequence": "MLESVSVLQASLEELGLCFPRDKAAADLGGAQTARAPPAKQKTQVNSCMPARATKPGRPPACTTKLSSAAASPLARPPAPRGLTSRVALTRRQGVGLRRQRRKMAATTGAGVKVPRNFRLLEELEEGQKGVGDGTVSWGLEDDEDMTLTRWTGMIIGPPRTIYENRIYSLKIECGPKYPEAPPFVRFVTKINMNGVNSSNGVVDPRAISVLAKWQNSFSIKVVLQELRRLMMSKENMKLPQPPEGQCYSN", "length": 250, "header": "tr|A0A8V0YR84-1|A0A8V0YR84_CHICK Isoform 1 of Ubiquitin conjugating enzyme E2 V1 OS=Gallus gallus OX=9031 GN=UBE2V1 PE=4 SV=1 CANONICAL=A0A8V0YR84-1" }, "locus": { "chromosome": "20", "start_pos": 14093924, "end_pos": 14081048, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010035294.1", "url": "https://www.ensembl.org/id/ENSGALT00010035294.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020551.1", "url": "https://www.ensembl.org/id/ENSGALP00010020551.1" } ] } }, { "isoform_ac": "A0A8V0YW76-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YR84/entry#A0A8V0YW76-1", "sequence": { "sequence": "MFSGRVKVPRNFRLLEELEEGQKGVGDGTVSWGLEDDEDMTLTRWTGMIIGPPRTIYENRIYSLKIECGPKYPEAPPFVRFVTKINMNGVNSSNGVVDPRAISVLAKWQNSFSIKVVLQELRRLMMSKENMKLPQPPEGQCYSN", "length": 144, "header": "tr|A0A8V0YW76-1|A0A8V0YW76_CHICK Computationally mapped isoform of Ubiquitin conjugating enzyme E2 V1 OS=Gallus gallus OX=9031 GN=UBE2V1 PE=4 SV=1 CANONICAL=A0A8V0YR84-1" }, "locus": { "chromosome": "20", "start_pos": 14093924, "end_pos": 14088978, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010035256.1", "url": "https://www.ensembl.org/id/ENSGALT00010035256.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020539.1", "url": "https://www.ensembl.org/id/ENSGALP00010020539.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A8D0V9S7-1", "protein_name": "Ubiquitin conjugating enzyme E2 V1", "gene_name": "UBE2V1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAATTGSGVKVPRNFRLLEELEEGQKGVGDGTVSWGLEDDEDMTLTRWTGMIIGPPRTIYENRIYSLKIECGPKYPEAPPFVRFVTKINMNGVNSSNGVVDPRAISVLAKWQNSYSIKVVLQELRRLMMSKENMKLPQPPEGQCYSN", "length": 147 }, "evidence": [ { "id": "A0A8V0YR84", "url": "https://omabrowser.org/oma/group/A0A8V0YR84/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0AAA9T5D9-1", "protein_name": "Ubiquitin conjugating enzyme E2 V1", "gene_name": "UBE2V1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MLLSRFSRVRLCATPETAAHQAPRSLGFSRQEHWSGLPFPSPVRESESEIAQSYPTPSDPMDCSLPKLLCPWDLPGVKVPRNFRLLEELEEGQKGVGDGTVSWGLEDDEDMTLTRWTGMIIGPPRTIYENRIYSLKIECGPKYPEAPPFVRFVTKINMNGVNSSNGVVDPRAISVLAKWQNSYSIKVVLQELRRLMMSKENMKLPQPPEGQCYSN", "length": 215 }, "evidence": [ { "id": "A0A8V0YR84", "url": "https://omabrowser.org/oma/group/A0A8V0YR84/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P53152-1", "protein_name": "Ubiquitin-conjugating enzyme variant MMS2", "gene_name": "MMS2", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSKVPRNFRLLEELEKGEKGFGPESCSYGLADSDDITMTKWNGTILGPPHSNHENRIYSLSIDCGPNYPDSPPKVTFISKINLPCVNPTTGEVQTDFHTLRDWKRAYTMETLLLDLRKEMATPANKKLRQPKEGETF", "length": 137 }, "evidence": [ { "id": "A0A8V0YR84", "url": "https://omabrowser.org/oma/group/A0A8V0YR84/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q13404-4", "protein_name": "Ubiquitin-conjugating enzyme E2 variant 1", "gene_name": "UBE2V1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAATTGSGVKVPRNFRLLEELEEGQKGVGDGTVSWGLEDDEDMTLTRWTGMIIGPPRTIYENRIYSLKIECGPKYPEAPPFVRFVTKINMNGVNSSNGVVDPRAISVLAKWQNSYSIKVVLQELRRLMMSKENMKLPQPPEGQCYSN", "length": 147 }, "evidence": [ { "id": "A0A8V0YR84", "url": "https://omabrowser.org/oma/group/A0A8V0YR84/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q54D06-1", "protein_name": "Probable ubiquitin-conjugating enzyme E2 variant", "gene_name": "ube2v", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MTTIPRNFVLLEELESGEKSTGDGTISYGLESPDDILLSSWIGTIIGPQNTPFDNRFYSLKLYCDKDYPNKPPTVRFTTKINIGCVNQQNGVVDPKNLPILSNWTSKNRIQNILSELRREMSSSSNKKLVQPPEGANF", "length": 138 }, "evidence": [ { "id": "A0A8V0YR84", "url": "https://omabrowser.org/oma/group/A0A8V0YR84/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q9CZY3-1", "protein_name": "Ubiquitin-conjugating enzyme E2 variant 1", "gene_name": "Ube2v1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAATTGSGVKVPRNFRLLEELEEGQKGVGDGTVSWGLEDDEDMTLTRWTGMIIGPPRTIYENRIYSLKIECGPKYPEAPPSVRFVTRVNMSGVSSSNGVVDPRATAVLAKWQNSHSIKVILQELRRLMMSKENMKLPQPPEGQCYSN", "length": 147 }, "evidence": [ { "id": "A0A8V0YR84", "url": "https://omabrowser.org/oma/group/A0A8V0YR84/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VRL1-1", "protein_name": "Ubiquitin-conjugating enzyme variant 1A, isoform C", "gene_name": "Uev1A", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MANTSSTGVVVPRNFRLLEELDQGQKGVGDGTISWGLENDDDMTLTYWIGMIIGPPRTPFENRMYSLKIECGERYPDEPPTLRFITKVNINCINQNNGVVDHRSVQMLARWSREYNIKTMLQEIRRIMTMKENLKLAQPPEGSCF", "length": 145 }, "evidence": [ { "id": "A0A8V0YR84", "url": "https://omabrowser.org/oma/group/A0A8V0YR84/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 197, "end_pos": 199, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YR84", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YR84" }, { "id": "PS50127", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50127" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "UBC core", "eco_id": "ECO_0000259", "start_pos": 115, "end_pos": 250, "start_aa": "Pro", "end_aa": "Asn", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 197, "end_pos": 199 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YPJ3-1", "uniprot_ac": "A0A8V0YPJ3", "uniprot_id": "A0A8V0YPJ3_CHICK", "mass": { "chemical_mass": 193745.0, "monoisotopic_mass": 193745.0 }, "refseq": { "ac": "XP_046796640", "name": "arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 2 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046796640" }, "gene_names": [ { "name": "ARAP2", "type": "recommended", "evidence": [ { "id": "A0A8V0YPJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPJ3" } ] }, { "name": "ARAP2", "type": "synonym", "evidence": [ { "id": "XP_046796640", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046796640" } ] } ], "protein_names": [ { "name": "ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2", "type": "synonym", "evidence": [ { "id": "A0A8V0YPJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPJ3/entry#names_and_taxonomy" } ] }, { "name": "arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 2 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_046796640", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046796640" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052535.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_046796640", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046796640" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPJ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPJ3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ARAP2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPJ3", "locus": { "chromosome": "4", "start_pos": 69830550, "end_pos": 69715169, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010014705", "url": "https://www.ensembl.org/id/ENSGALG00010014705" } ] } } ], "crossref": [ { "id": "cd04385", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04385", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd08856", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd08856", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd09490", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09490", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd13253", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13253", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd17227", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd17227", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "428790", "url": "https://www.ncbi.nlm.nih.gov/gene/428790", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000159", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000159", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000198", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000198", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001164", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001164", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001660", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001660", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001849", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001849", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008936", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008936", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013761", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013761", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037278", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037278", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037858", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037858", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038508", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038508", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052227", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052227", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:428790", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:428790", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "FAHSCET", "url": "https://omabrowser.org/oma/group/FAHSCET/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YI51", "url": "https://www.orthodb.org/?gene=A0A8V0YI51", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YPJ0", "url": "https://www.orthodb.org/?gene=A0A8V0YPJ0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YPJ3", "url": "https://www.orthodb.org/?gene=A0A8V0YPJ3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YPK4", "url": "https://www.orthodb.org/?gene=A0A8V0YPK4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45899", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45899", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45899:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45899:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00169", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00169", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00620", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00620", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00788", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00788", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01412", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01412", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07647", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07647", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-8980692", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8980692", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9013148", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013148", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9013149", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013149", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9013423", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013423", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_046796640", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046796640", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YI51", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI51", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YI51-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI51-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YPJ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPJ0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YPJ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPJ0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YPJ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPJ3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YPJ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPJ3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YPK4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPK4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YPK4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPK4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTVRANIRNEAAIMSSTGSDIDIEEFLVNINLGQYLPNFKEHGYNVVTDCVGINNSALQQMGVLPTGHRRRILKQLDTALSKMQGNSLPRDNLKLKVLKGLEKKQYSFSDEDSPVSHLNVDESGLIPATSLVQLPNKAYIGKERSRLGEQYLLEANDESFTNSDFPSLYRGSDSVLKTVSGSMKMNTESNTLLEKAAAYQTDEHLADCVAFCDPLSLTHSYETKYKENKHQMFAVEEDLCDSEPHSPFVKFKGEMIDNDLYDSCTQNCVKVFPRTSRSFILRHRPVPEIPESSKVDTSSSSLQKRRNVDLIDVSCAGRQVSQKKTSSEEKPPVISPYGETYFWDNLKDAKELHRNEFLACENKSDLEMPEEYSSNKNICSLNNQDEKTKECVKNESLSQENKSLPPEDFESEPVYSIVDQCSFSSKKNKNKTQTHSSSCSKNQSGKSNWLVSEQMDSQQFDGGQTSIANESIAPYACFYGSSVKKVKAGWLDKLSPQGKRMFQKRWVKFDGDSISYYNNEKEVFSKGIILLSAIATVRVHGENKFEVVTSHRTFVFRVDKEEERNDWVNKILNAVKSQSDNNPQSRISVAPEKSGYLELKGYKAKIFILLQGNTVWICKNEQDFKTGFGITLIPMNVANVKQVDRAAKPSFEIITPYKSFSFTAESEREKQDWIEALQQSIAETLSDYEVAEKIWFNESNRSCADCKAPNPDWASINLCVVICKKCAGQHRSLGPRDSKVRSLKMDASIWSNELIELFIIIGNKRANSFWAGNLPPDEELHMDAPAEKRIAFITQKYKEGKFRKTPFPYKTKEQLNKALCAAVVKQDVLETLMLLFSGADVMCATGDPVYSTPYLLAKKAGQRLQMEFLYHNKFSDFPNYDTSFESGFSEDSSHSTFLCEFLYKVSSNSTKLLTEKKLKEDCNKRWCTLESGFLSYYENDKATTPNGMLDINEVICLVVHNSEYFLNRGDIFTFEIYLMSERVFLFGAETAYSQRKWTWAIAKHFVPPVAECLLERDCDLIGQLYYKDCHNLDQWRKGWFAIEKSSLHFCLEMENAQEDSIYLRRLQELTISSVMQNGEKIDVLLLVEKGRTLYIHGHTKLDFIVWYTAIEKAAGTDGNALQDQQLSKNDVPIIVNSCIAFVTQYGLGSKHIYLKNGNSSNVAELLESFKKDARSVKLRAGKHQLEDVTDVLKSFLSQIDDAILTKELYPFWISALDMQNEKERVMKYGAFIRTLPPVNKATLAALIEHLYRVQKCSEINHMNPHNLALVFSSCLFQTKGQTSEEVSVIEDLIKNYVQLFDVNEDQVKQMDIENSFITRWKDTQVSQAGDLLIEVYVERKEPDCSIIIRVSPLTEAEELTNDILGIKNITPNKDDIWATFEVLENGELERPLHYTENVLEQVLHWSSLPEPGTAYLIIKRFLTADMMKLYNERNVKGSVKAGYLKYKEEPSKLLSGNKFQERYFVLREGNLLLYKDMKASKPEKVLPVNSLKLYLGVKKKMKPPTNWGIVAISEKHQWHICCDGQEAQIDWMISIFTAKHANIWPPAGKARKQSITKSPKIGGLQLIPIQQEKNTCKIRGSTEDIQLRLGKPKCDEHNEVDLVEERKNLKEKASIVAQCLERKEEKVQNHAKTHRSFVSVEDMGVGMADLRQRSHKPPKKAKNKTNKTTLELDNKLPSNVIQELNTVLQKNRILHDETSS", "length": 1700, "header": "tr|A0A8V0YPJ3-1|A0A8V0YPJ3_CHICK Isoform 1 of ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 OS=Gallus gallus OX=9031 GN=ARAP2 PE=4 SV=1 CANONICAL=A0A8V0YPJ3-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YI51-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPJ3/entry#A0A8V0YI51-1", "sequence": { "sequence": "MTVRANIRNEAAIMSSTGSDIDIEEFLVNINLGQYLPNFKEHGYNVVTDCVGINNSALQQMGVLPTGHRRRILKQLDTALSKMQGNSLPRDNLKLKVLKGLEKKQYSFSDEDSPVSHLNVDESGLIPATSLVQLPNKAYIGKERSRLGEQYLLEANDESFTNSDFPSLYRGSDSVLKTVSGSMKMNTESNTLLEKAAAYQTDEHLADCVAFCDPLSLTHSYETKYKENKHQMFAVEEDLCDSEPHSPFVKFKGEMIDNDLYDSCTQNCVKVFPRTSRSFILRHRPVPEIPESSKVDTSSSSLQKRRNVDLIDVSCAGRQVSQKKTSSEEKPPVISPYGETYFWDNLKDAKELHRNEFLACENKSDLEMPEEYSSNKNICSLNNQDEKTKECVKNESLSQENKSLPPEDFESEPVYSIVDQCSFSSKKNKNKTQTHSSSCSKNQSGKSNWLVSEQMDSQQFDGGQTSIANESIAPYACFYGSSVKKVKAGWLDKLSPQGKRMFQKRWVKFDGDSISYYNNEKEVFSKGIILLSAIATVRVHGENKFEVVTSHRTFVFRVDKEEERNDWVNKILNAVKSQSDNNPQSRISVAPEKSGYLELKGYKAKIFILLQGNTVWICKNEQDFKTGFGITLIPMNVANVKQVDRAAKPSFEIITPYKSFSFTAESEREKQDWIEALQQSIAETLSDYEVAEKIWFNESNRSCADCKAPNPDWASINLCVVICKKCAGQHRSLGPRDSKVRSLKMDASIWSNELIELFIIIGNKRANSFWAGNLPPDEELHMDAPAEKRIAFITQKYKEGKFRKTPFPYKTKEQLNKALCAAVVKQDVLETLMLLFSGADVMCATGDPVYSTPYLLAKKAGQRLQMEFLYHNKFSDFPNYDTSFESGFSEDSSHSTFLCEFLYKVSSNSTKLLTEKKLKEDCNKRWCTLESGFLSYYENDKATTPNGMLDINEVICLVVHNSEYFLNRGDIFTFEIYLMSERVFLFGAETAYSQRKWTWAIAKHFVPPVAECLLERDCDLIGQLYYKDCHNLDQWRKGWFAIEKSSLHFCLEMENAQEDSIYLRRLQELTISSVMQNGEKIDVLLLVEKGRTLYIHGHTKLDFIVWYTAIEKAAGTDGNALQDQQLSKNDVPIIVNSCIAFVTQYGLGSKHIYLKNGNSSNVAELLESFKKDARSVKLRAGKHQLEDVTDVLKSFLSQIDDAILTKELYPFWISALDMQNEKERVMKYGAFIRTLPPVNKATLAALIEHLYRVQKCSEINHMNPHNLALVFSSCLFQTKGQTSEEVSVIEDLIKNYVQLFDVNEDQVKQMDIENSFITRWKDTQVSQAGDLLIEVYVERKEPDCSIIIRVSPLTEAEELTNDILGIKNITPNKDDIWATFEVLENGELERPLHYTENVLEQVLHWSSLPEPGTAYLIIKRFLTADMMKLYNERNVKGSVKAGYLKYKEEPSKLLSGNKFQERYFVLREGNLLLYKDMKASKPEKVLPVNSLKLYLGVKKKMKPPTNWGIVAISEKHQWHICCDGQEAQIDWMISIFTAKDIQLRLGKPKCDEHNEVDLVEERKNLKEKASIVAQCLERKEEKVQNHAKTHRSFVSVEDMGVGMADLRQRSHKPPKKAKNKTNKTTLELDNKLPSNVIQELNTVLQKNRILHDETSS", "length": 1656, "header": "tr|A0A8V0YI51-1|A0A8V0YPJ3_CHICK Computationally mapped isoform of ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 OS=Gallus gallus OX=9031 GN=ARAP2 PE=4 SV=1 CANONICAL=A0A8V0YPJ3-1" }, "locus": { "chromosome": "4", "start_pos": 69829705, "end_pos": 69721220, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010035346.1", "url": "https://www.ensembl.org/id/ENSGALT00010035346.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020573.1", "url": "https://www.ensembl.org/id/ENSGALP00010020573.1" } ] } }, { "isoform_ac": "A0A8V0YPJ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPJ3/entry#A0A8V0YPJ0-1", "sequence": { "sequence": "MTVRANIRNEAAIMSSTGSDIDIEEFLVNINLGQYLPNFKEHGYNVVTDCVGINNSALQQMGVLPTGHRRRILKQLDTALSKMQGNSLPRDNLKLKVLKGLEKKQYSFSDEDSPVSHLNVDESGLIPATSLVQLPNKAYIGKERSRLGEQYLLEANDESFTNSDFPSLYRGSDSVLKTVSGSMKMNTESNTLLEKAAAYQTDEHLADCVAFCDPLSLTHSYETKYKENKHQMFAVEEDLCDSEPHSPFVKFKGEMIDNDLYDSCTQNCVKVFPRTSRSFILRHRPVPEIPESSKVDTSSSSLQKRRNVDLIDVSCAGRQVSQKKTSSEEKPPVISPYGETYFWDNLKDAKELHRNEFLACENKSDLEMPEEYSSNKNICSLNNQDEKTKECVKNESLSQENKSLPPEDFESEPVYSIVDQCSFSSKKNKNKTQTHSSSCSKNQSGKSNWLVSEQMDSQQFDGGQTSIANESIAPYACFYGSSVKKVKAGWLDKLSPQGKRMFQKRWVKFDGDSISYYNNEKEVFSKGIILLSAIATVRVHGENKFEVVTSHRTFVFRVDKEEERNDWVNKILNAVKSQSDNNPQSRISVAPEKSGYLELKGYKAKIFILLQGNTVWICKNEQDFKTGFGITLIPMNVANVKQVDRAAKPSFEIITPYKSFSFTAESEREKQDWIEALQQSIAETLSDYEVAEKIWFNESNRSCADCKAPNPDWASINLCVVICKKCAGQHRSLGPRDSKVRSLKMDASIWSNELIELFIIIGNKRANSFWAGNLPPDEELHMDAPAEKRIAFITQKYKEGKFRKTPFPYKTKEQLNKALCAAVVKQDVLETLMLLFSGADVMCATGDPVYSTPYLLAKKAGQRLQMEFLYHNKFSDFPNYDTSFESGFSEDSSHSTFLCEFLYKVSSNSTKLLTEKKLKEDCNKRWCTLESGFLSYYENDKATTPNGMLDINEVICLVVHNSEYFLNRGDIFTFEIYLMSERVFLFGAETAYSQRKWTWAIAKHFVPPVAECLLERDCDLIGQLYYKDCHNLDQWRKGWFAIEKSSLHFCLEMENAQEDSIYLRRLQELTISSVMQNGEKIDVLLLVEKGRTLYIHGHTKLDFIVWYTAIEKAAGTDGNALQDQQLSKNDVPIIVNSCIAFVTQYGLGSKHIYLKNGNSSNVAELLESFKKDARSVKLRAGKHQLEDVTDVLKSFLSQIDDAILTKELYPFWISALDMQNEKERVMKYGAFIRTLPPVNKATLAALIEHLYRVQKCSEINHMNPHNLALVFSSCLFQTKGQTSEEVSVIEDLIKNYVQLFDVNEDQVKQMDIENSFITRWKDTQVSQAGDLLIEVYVERKEPDCSIIIRVSPLTEAEELTNDILGIKNITPNKDDIWATFEVLENGELERPLHYTENVLEQVLHWSSLPEPGTAYLIIKRFLTADMMKLYNERNVKGSVKAGYLKYKEEPSKLLSGNKFQERYFVLREGNLLLYKDMKASKPEKVLPVNSLKLYLGVKKKMKPPTNWGIVAISEKHQWHICCDGQEAQIDWMISIFTAKHANIWPPAGKARKQSITKSPKIGGLQLIPIQQEKNTCKIRGSTEMAAERQCDRIDV", "length": 1595, "header": "tr|A0A8V0YPJ0-1|A0A8V0YPJ0_CHICK Computationally mapped isoform of ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 OS=Gallus gallus OX=9031 GN=ARAP2 PE=4 SV=1 CANONICAL=A0A8V0YPJ3-1" }, "locus": { "chromosome": "4", "start_pos": 69825060, "end_pos": 69721220, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010035327.1", "url": "https://www.ensembl.org/id/ENSGALT00010035327.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020565.1", "url": "https://www.ensembl.org/id/ENSGALP00010020565.1" } ] } }, { "isoform_ac": "A0A8V0YPJ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPJ3/entry#A0A8V0YPJ3-1", "sequence": { "sequence": "MTVRANIRNEAAIMSSTGSDIDIEEFLVNINLGQYLPNFKEHGYNVVTDCVGINNSALQQMGVLPTGHRRRILKQLDTALSKMQGNSLPRDNLKLKVLKGLEKKQYSFSDEDSPVSHLNVDESGLIPATSLVQLPNKAYIGKERSRLGEQYLLEANDESFTNSDFPSLYRGSDSVLKTVSGSMKMNTESNTLLEKAAAYQTDEHLADCVAFCDPLSLTHSYETKYKENKHQMFAVEEDLCDSEPHSPFVKFKGEMIDNDLYDSCTQNCVKVFPRTSRSFILRHRPVPEIPESSKVDTSSSSLQKRRNVDLIDVSCAGRQVSQKKTSSEEKPPVISPYGETYFWDNLKDAKELHRNEFLACENKSDLEMPEEYSSNKNICSLNNQDEKTKECVKNESLSQENKSLPPEDFESEPVYSIVDQCSFSSKKNKNKTQTHSSSCSKNQSGKSNWLVSEQMDSQQFDGGQTSIANESIAPYACFYGSSVKKVKAGWLDKLSPQGKRMFQKRWVKFDGDSISYYNNEKEVFSKGIILLSAIATVRVHGENKFEVVTSHRTFVFRVDKEEERNDWVNKILNAVKSQSDNNPQSRISVAPEKSGYLELKGYKAKIFILLQGNTVWICKNEQDFKTGFGITLIPMNVANVKQVDRAAKPSFEIITPYKSFSFTAESEREKQDWIEALQQSIAETLSDYEVAEKIWFNESNRSCADCKAPNPDWASINLCVVICKKCAGQHRSLGPRDSKVRSLKMDASIWSNELIELFIIIGNKRANSFWAGNLPPDEELHMDAPAEKRIAFITQKYKEGKFRKTPFPYKTKEQLNKALCAAVVKQDVLETLMLLFSGADVMCATGDPVYSTPYLLAKKAGQRLQMEFLYHNKFSDFPNYDTSFESGFSEDSSHSTFLCEFLYKVSSNSTKLLTEKKLKEDCNKRWCTLESGFLSYYENDKATTPNGMLDINEVICLVVHNSEYFLNRGDIFTFEIYLMSERVFLFGAETAYSQRKWTWAIAKHFVPPVAECLLERDCDLIGQLYYKDCHNLDQWRKGWFAIEKSSLHFCLEMENAQEDSIYLRRLQELTISSVMQNGEKIDVLLLVEKGRTLYIHGHTKLDFIVWYTAIEKAAGTDGNALQDQQLSKNDVPIIVNSCIAFVTQYGLGSKHIYLKNGNSSNVAELLESFKKDARSVKLRAGKHQLEDVTDVLKSFLSQIDDAILTKELYPFWISALDMQNEKERVMKYGAFIRTLPPVNKATLAALIEHLYRVQKCSEINHMNPHNLALVFSSCLFQTKGQTSEEVSVIEDLIKNYVQLFDVNEDQVKQMDIENSFITRWKDTQVSQAGDLLIEVYVERKEPDCSIIIRVSPLTEAEELTNDILGIKNITPNKDDIWATFEVLENGELERPLHYTENVLEQVLHWSSLPEPGTAYLIIKRFLTADMMKLYNERNVKGSVKAGYLKYKEEPSKLLSGNKFQERYFVLREGNLLLYKDMKASKPEKVLPVNSLKLYLGVKKKMKPPTNWGIVAISEKHQWHICCDGQEAQIDWMISIFTAKHANIWPPAGKARKQSITKSPKIGGLQLIPIQQEKNTCKIRGSTEDIQLRLGKPKCDEHNEVDLVEERKNLKEKASIVAQCLERKEEKVQNHAKTHRSFVSVEDMGVGMADLRQRSHKPPKKAKNKTNKTTLELDNKLPSNVIQELNTVLQKNRILHDETSS", "length": 1700, "header": "tr|A0A8V0YPJ3-1|A0A8V0YPJ3_CHICK Isoform 1 of ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 OS=Gallus gallus OX=9031 GN=ARAP2 PE=4 SV=1 CANONICAL=A0A8V0YPJ3-1" }, "locus": { "chromosome": "4", "start_pos": 69829705, "end_pos": 69721220, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010035358.1", "url": "https://www.ensembl.org/id/ENSGALT00010035358.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020577.1", "url": "https://www.ensembl.org/id/ENSGALP00010020577.1" } ] } }, { "isoform_ac": "A0A8V0YPK4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPJ3/entry#A0A8V0YPK4-1", "sequence": { "sequence": "MTVRANIRNEAAIMSSTGSDIDIEEFLVNINLGQYLPNFKEHGYNVVTDCVGINNSALQQMGVLPTGHRRRILKQLDTALSKMQGNSLPRDNLKLKVLKGLEKKQYSFSDEDSPVSHLNVDESGLIPATSLVQLPNKAYIGKERSRLGEQYLLEANDESFTNSDFPSLYRGSDSVLKTVSGSMKMNTESNTLLEKAAAYQTDEHLADCVAFCDPLSLTHSYETKYKENKHQMFAVEEDLCDSEPHSPFVKFKGEMIDNDLYDSCTQNCVKVFPRTSRSFILRHRPVPEIPESSKVDTSSSSLQKRRNVDLIDVSCAGRQVSQKKTSSEEKPPVISPYGETYFWDNLKDAKELHRNEFLACENKSDLEMPEEYSSNKNICSLNNQDEKTKECVKNESLSQENKSLPPEDFESEPVYSIVDQCSFSSKKNKNKTQTHSSSCSKNQSGKSNWLVSEQMDSQQFDGGQTSIANESIAPYACFYGSSVKKVKAGWLDKLSPQGKRMFQKRWVKFDGDSISYYNNEKEVFSKGIILLSAIATVRVHGENKFEVVTSHRTFVFRVDKEEERNDWVNKILNAVKSQSDNNPQSRISVAPEKSGYLELKGYKAKIFILLQGNTVWICKNEQDFKTGFGITLIPMNVANVKQVDRAAKPSFEIITPYKSFSFTAESEREKQDWIEALQQSIAETLSDYEVAEKIWFNESNRSCADCKAPNPDWASINLCVVICKKCAGQHRSLGPRDSKVRSLKMDASIWSNELIELFIIIGNKRANSFWAGNLPPDEELHMDAPAEKRIAFITQKYKEGKFRKTPFPYKTKEQLNKALCAAVVKQDVLETLMLLFSGADVMCATGDPVYSTPYLLAKKAGQRLQMEFLYHNKFSDFPNYDTSFESGFSEDSSHSTFLCEFLYKVSSNSTKLLTEKKLKEDCNKRWCTLESGFLSYYENDKATTPNGMLDINEVICLVVHNSEYFLNRGDIFTFEIYLMSERVFLFGAETAYSQRKWTWAIAKHFVPPVAECLLERDCDLIGQLYYKDCHNLDQWRKGWFAIEKSSLHFCLEMENAQEDSIYLRRLQELTISSVMQNGEKIDVLLLVEKGRTLYIHGHTKLDFIVWYTAIEKAAGTDGNALQDQQLSKNDVPIIVNSCIAFVTQYGLGSKHIYLKNGNSSNVAELLESFKKDARSVKLRAGKHQLEDVTDVLKSFLSQIDDAILTKELYPFWISALDMQNEKERVMKYGAFIRTLPPVNKATLAALIEHLYRVQKCSEINHMNPHNLALVFSSCLFQTKGQTSEEVSVIEDLIKNYVQLFDVNEDQVKQMDIENSFITRWKDTQVSQAGDLLIEVYVERKEPDCSIIIRVSPLTEAEELTNDILGIKNITPNKDDIWATFEVLENGELERNVKGSVKAGYLKYKEEPSKLLSGNKFQERYFVLREGNLLLYKDMKASKPEKVLPVNSLKLYLGVKKKMKPPTNWGIVAISEKHQWHICCDGQEAQIDWMISIFTAKHANIWPPAGKARKQSITKSPKIGGLQLIPIQQEKNTCKIRGSTEDIQLRLGKPKCDEHNEVDLVEERKNLKEKASIVAQCLERKEEKVQNHAKTHRSFVSVEDMGVGMADLRQRSHKPPKKAKNKTNKTTLELDNKLPSNVIQELNTVLQKNRILHDETSS", "length": 1657, "header": "tr|A0A8V0YPK4-1|A0A8V0YPK4_CHICK Computationally mapped isoform of ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 OS=Gallus gallus OX=9031 GN=ARAP2 PE=4 SV=1 CANONICAL=A0A8V0YPJ3-1" }, "locus": { "chromosome": "4", "start_pos": 69829705, "end_pos": 69721220, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010035373.1", "url": "https://www.ensembl.org/id/ENSGALT00010035373.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020587.1", "url": "https://www.ensembl.org/id/ENSGALP00010020587.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:428790", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:428790", "resource": "KEGG Pathway" }, { "id": "R-GGA-8980692", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8980692", "resource": "Reactome", "description": "RHOA GTPase cycle" }, { "id": "R-GGA-9013148", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013148", "resource": "Reactome", "description": "CDC42 GTPase cycle" }, { "id": "R-GGA-9013149", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013149", "resource": "Reactome", "description": "RAC1 GTPase cycle" }, { "id": "R-GGA-9013423", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013423", "resource": "Reactome", "description": "RAC3 GTPase cycle" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3Q1LV13-1", "protein_name": "Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 2", "gene_name": "ARAP2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSSVSEVNVDIRDFLMSINLEQYLLNFREFGFNNVRDCAEINDSVLLKVGISPTGHRRRILKQLQIILSKMQDIPIYANIHKTKKNDETSKDHQAPSSAQNTSLEFSDSHGVQIPSRIQLETVTKNVGENEVCVENSQSLKSDDKLTLPTHNFPIPEDEPHSNSGSFQDSLLRNEITDIESLITEKTVGCTAEEEHTGRDDLISENVGKLPNADLEFLSSHDSSVSEANSGNGTNVLLESSPPSPFFQFQGEMVVNDLYVPSSPVLTPMRSRSKLVSRPSRSFLLRHRPVPEIPGSTKGISGSYFRERRNVATSTGKSVTQQNTNEENSSSILPYGETFLLQRLENSKKRSIKNEFWTQEETLKGETTTERNSFFVKSSIYDNRTENISENKVEDIWIPREDKSNLPIDSASESEYSTVEECFQSLRRKNSKPSKSRTQKAANLDPVNRHSYPLSSTSGNADSPVISSNVISPYACFYGSSTRKVKSGWLDKLCPQGKRMFQKRWVKFDGLSISYYNNDKEKYSKGIIPLSAISTVRVQGDNKFEVVTTQRTFVFRVEKEEERNDWISLLLNALKLQALSSQSQAAIAPEKCGYLELRGYKAKIFTVLSGNSVWLCKNEQDFKSGLGITIIPMNVANVKQVDRTVKQSFEIITPYRSFSFTAESEKEKQEWIEAVQQSIAETLSDYEVAEKIWYNESNRSCADCKAPDPDWASINLCVVICKKCAGQHRSLGPKDSKVRSLKMDASIWSNELIELFIVIGNKRANDFWAGNLQKDEELHMDCSVEKRKNFITQKYKEGRFRKTLLASLTKEELNKALCAAVVKPDVLETMALLFSGADVMCATGDPEHSTPYLLAKKAGQSLQMEFLYHNKFSDFPQHDIYSEGRLNQESSQSTFLCDFLYQAPAGASKLSSEKKLLEETNKKWCVLEGGFLSYYENDKSTTPNGTININEVICLAVHKEDFCLNTGPIFTFEIYLPSERAFLFGAETSQVQRKWTEAIAKHFVPFVAENLTEADYDLIGQLYYKDCHALDQWRKGWFAMDKSNLRFCLPMQEGQEDRMHLRRLQELTISTVVQNGEKLDVLLLVEKGRTLYIHGHTKLDFTVWHTAIEKAAGTDGNALQDQQLGRNDVPIIVNSCIAFVTQYGLGYKNIYQKNGDPLHVSELLESFKKDARSFKLRAGKHQLEDVTGVLKSFLSDIDDALLTKELYPYWISALDTQDDKERIKKYGAFIRTLPGVNRATLAAIIEHLYRVQKCSEINHMSAHNLALVFSSCFFQTKGQTSEEVNVIEDLINNYVEIFEVKEDQVKQMDIENSFITKWKDTQVSQAGDLLIEVYVERKEPDCSIIIRISPVMEAEELTNDILAIKNIIPTKDDIWATFEVIENEELERPLHYTENVLEQVLRWSSLAEPGSAYLVVKRFLTIDTIKHYNERKALENIKEGVLKVKEEPSKILSGNKFQDRYCVLRDGYLLLYKDLKSSKPDKMFSLSSVKFYLGVKKKMKPPTSWGLTAYSEKHHWHLCCESSQTQTEWMANIFIAQHENDIWPPAGKERKRSITKNPKIGGLPLIPIQHDRNATQARRETESAKAELERLRLGAKRDQGGDGTLKEKASIVAQCLEHKDEKLRNRTRKHRSFNCLEDTEAEVFPGRQKGHKGLKTLRKTEDRNGKDTLDCNNKLPPKVIEELSVVLQRSRTLPKELQDEQVVQKEIK", "length": 1708 }, "evidence": [ { "id": "A0A8V0YPJ3", "url": "https://omabrowser.org/oma/group/A0A8V0YPJ3/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0ABK0LIB6-1", "protein_name": "Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 2", "gene_name": "Arap2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSAVSEVNVDIQDFLMSINLEQYLLHFQEFGFYTVKDCTSINDNVLHQIGISPTGHRRRILKQLQMIFSKMQDFPIYANVYKTKNGSTPKEQHSAPSSSSNTCIEFSDSVTVHRPGPAPSEMVTTNVLSEGNCHSSTSHDKLSLSSSDLPCPEEEICQNVDSSQDYLFGRVNVKIDSLITQQAVEHTAGEEQTEKVNLVSEDSSKALNTNTECLPSVDHPASETHCGNGTNGVLESFPPSPFFQFQGEMVVNELYVPSSPIHSPMRSRSKLVSRPSRSFLLRHRPVPEIPGSTKSISGSYFRDRKSITTSAGKSLTLKDANEDNSTSIFPYGETFLFQRLESSKKRSIKNEFWAHEDTVKEEAATSRNSILTKSSIYDSRKEKVSEDKVEDIWIPREDKNNLPQDSASESEYSTVEECFQSLRRKNSKASKSRTQKAFYLDPFNRHSYPLSSTSENTDPSTIANAISPYACFYGSSAAKVKSGWLDKLSPQGKRMFQKRWVKFDGLSISYYNNDREMYSKGIIPLTAISTVRAQGDNKFEIVTTQRTFVFRVEKEEERNDWISVLLSALKSPSLTSQLQAAVAPEKCGYLELRGYKAKIFTVLRGNSVWLCKTEQDFKSGLGITIIPMNVANVKQIDRAVKQSFEIITPYRSFSFTADSEKEKQEWIEAVQQSIAETLSDYEVAEKIWFNESNRSCADCKAPDPDWASINLCVVICKKCAGQHRSLGPKDSKVRSLKMDASIWSNELIELFIVIGNKRANDFWAGNLKKDEEIQMDSPVDKRKIFITQKYKEGKFRKTFLASLTKEELNKALCAAVVKPDVLETMALLFSGADVMCATGDPVHCTPYLLAKKAGQSLQMEFLYHNKFSDFPQYDAHSEGGSSQEATQSTFLCDFLYQATASASRVSTEKKLLEETNKKWCVLEGGFLSYYENDRCTTPNGTINISEVICLTVHKEDFYLNTGPIFIFEIYLPSERVFLFGAKTSQIQRKWTETIAKRFVPFVAENLTEADYDLIGQLFYKDCHALDQWRKGWFAMDKSSLCFCLQTQEAQEERMHLRRLQELTISTVVQNGEKVDVLLLVEKGRTLYIHGYTKLDFTVWRNAIEKAAGTDGNTLQDQQLCKNDVPIIVNSCIAFVTQYGLGCKYIYQKDGDPLSISELLESFKKDARSVKLRVGKHQLEDVTGVLKSFLSDIDDALLTKELYPYWVSALDAQDEKQRTDKYRAFICSLPGVNRATLAALIEHLYRVQKCSEINHMNAHNLALVFSSCLFQTKGQTSEEVNVIEDLINNYVEIFEVKEDQVKQMDIENSFITKWKNTQASVHCLMKSLERLKVSQAGDLLIEVFAERKEPDCSIIIRVSPVMEAEELTNDILAIKNILPTKGDIWATFEVIENEELERPLHYTENVLEQVLQWSSLAEPGSAYLVVKRFLTIDTIKQCREKSIKEGILKLKEEPSKILSGNKFQDRCVVLRDGHLFIYKDPKSTKHEKMFPLRLMKFYLGVKKKMKPPTSWGLTACSEKHHWHLCCDSLQAQMEWMASIFIAQHENDIWPPAGKERKRSITKNPKIGGLPLIPIQHEKNATQARKNIEMARAELERLRLSERHDGDFTDSSLKDRASIIGYCLEHKDEKLRNRARKHRSFNCLEDTEAEVPPGLPKGYKGLKTVKKTEDRNSKATLEPNNKLPSKVIEELSVVLQRSRSHPKELPDEQTL", "length": 1709 }, "evidence": [ { "id": "A0A8V0YPJ3", "url": "https://omabrowser.org/oma/group/A0A8V0YPJ3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8BZ05-1", "protein_name": "Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 2", "gene_name": "Arap2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSVSEVNADIRDFLMSINLEQYLLHFREFGFYTVRDCTSINDSVLHQIGISPTGHRRRILKQLQMIFSKMQDFPIYANVHKAKNGSTTKEQQHSDPSSSTHTGIECSDSITVHRPGPAPSEMVTTSTLSEGNCQSPKSHDKLCLSSHDLLCPEEELHQNVDSSKDSLFGGVNVKIDPLITKRAVEYTAGEEHTEKGNLTSEDSSKALSTNTECLPSGDCPTSGTHSGNGTNGVLESFPPTPFFQFQGEMVVNELYVPSSPVHGPMRSRSKLVSRPSRSFLLRHRPVPEIPGSTKSIPGSYFRDRRSNTTSAGKSLTLKNSNEDNSTSIFPYGETFLFQRLESSKKRSIKNEFWPHENTVKEEAATTRNSILTQSSIYDNRKEKVSEDKVEDIWIPREDKNNLAQDSASESEYSTVEECFQSLRRKNSKASKSRTQKAFYLDPFNRHSYPLSSTSGNTEPSSTISNAISPYACFYGSSAAKEKCGWLDKLSPQGKRMFQKRWVKFDGLSISHYNNDREMYSKGIIPLTAISTVRAQGDNKFEIVTTQRTFVFRVEKEEERNDWISILLSALKSPSLASQLQAAVAPEKCGYLELRGYKAKIFTVLRGNSVWLCKNEQDFKSGLGITIIPMNVANVKQVDRAVKQSFEIITPYRSFSFTADSEREKQEWIEAVQQSIAETLSDYEVAEKIWFNESNRSCADCKAPDPDWASINLCVVICKKCAGQHRSLGPKDCKVRSLKMDASIWSNELIELFIVIGNKRANDFWAGNLQKDEELQVDSPVEKRKNFITQKYKEGKFRKTLLASLTKEELNKALCAAVVKPDVLETMALLFSGADVMCATGDPVHSTPYLLAKKAGQSLQMEFLYHNKFSDFPQYDAHFEGGSSQDAAQSSFLCDFLYQTAAAASRVSSEKKLLEDTNKKWCVLEGGFLSYYENDRCTTPNGTINISEVICLAVHKEDFYLNTGPIFVFEIYLPSERVFLFGAETSQIQRKWTETIAKRFVPFVAENLTEADYDLIGQLFYKDCHALDQWRKGWFAMDKSSLCFCLQTQEAQEERMNLRRLQELTISTMVQNGEKVDVLLLVEKGRTLYIHGHTKLDFTVWHTAIEKAAGTDGNALQDQQLCKNDVPIIVNSCIAFVTQYGLGCKYIYQKDGDPLHISELLESFKKDARSVKLRAGKHQLEDVTGVLKSFLSDIDDALLTKELYPYWVSALDTQDEKERTSKYRAFIRSLPGVNRATLAALIEHLYRVQKCSEINHMNAHNLAMVFSSCLFQTKGQTSEEVNVIEDLINNYVEIFEVKEDQVKQMDIENSFITKWKDTQVSQAGDLLIEVFVERKEPDCSIIIRISPVMEAEELTNDILAIKNIIPMKGDIWATFEVIENEELERPLHYTENVLEQVLQWSSLAEPGSAYLVVKRFLTVDSIKQCREKSIKEGILKLKEEPSKILSGNKFQDRCVVLRDGHLFIYKDPKSSKHDKMFPLRAMKFYLGVKKKMKPPTSWGLTVYSEKHHWHLCCDSLQAQMEWMASIFIAQHENDIWPPAGKERKRSITKNPKIGGLPLIPIQHERNATQARKNIETARAELERLRLSEKHDPRDFTDSSLKDRASLIAHCLEHKDEKLRNRARKHRSFNCLEDTEAEGPHGLPKAYKGPKTLKKTEERNSKATLDADPKLPSKVIEELSVVLQRSRPLHKELPDEQTLQKEVK", "length": 1703 }, "evidence": [ { "id": "A0A8V0YPJ3", "url": "https://omabrowser.org/oma/group/A0A8V0YPJ3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8WZ64-1", "protein_name": "Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 2", "gene_name": "ARAP2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSSVSEVNVDIKDFLMSINLEQYLLHFHESGFTTVKDCAAINDSLLQKIGISPTGHRRRILKQLQIILSKMQDIPIYANVHKTKKNDDPSKDYHVPSSDQNICIELSNSGSVQTSSPPQLETVRKNLEDSDASVERSQYPQSDDKLSPPKRDFPTAEEPHLNLGSLNDSLFGSDNIKIESLITKKTVDHTVEEQQTEKVKLITENLSKLPNADSECLSFVGCSTSGTNSGNGTNGLLEGSPPSPFFKFQGEMIVNDLYVPSSPILAPVRSRSKLVSRPSRSFLLRHRPVPEIPGSTKGVSGSYFRERRNVATSTEKSVAWQNSNEENSSSIFPYGETFLFQRLENSKKRSIKNEFLTQGEALKGEAATATNSFIIKSSIYDNRKEKISEDKVEDIWIPREDKNNFLIDTASESEYSTVEECFQSLRRKNSKASKSRTQKALILDSVNRHSYPLSSTSGNADSSAVSSQAISPYACFYGASAKKVKSGWLDKLSPQGKRMFQKRWVKFDGLSISYYNNEKEMYSKGIIPLSAISTVRVQGDNKFEVVTTQRTFVFRVEKEEERNDWISILLNALKSQSLTSQSQAVVTPEKCGYLELRGYKAKIFTVLSGNSVWLCKNEQDFKSGLGITIIPMNVANVKQVDRTVKQSFEIITPYRSFSFTAETEKEKQDWIEAVQQSIAETLSDYEVAEKIWFNESNRSCADCKAPDPDWASINLCVVICKKCAGQHRSLGPKDSKVRSLKMDASIWSNELIELFIVIGNKRANDFWAGNLQKDEELHMDSPVEKRKNFITQKYKEGKFRKTLLASLTKEELNKALCAAVVKPDVLETMALLFSGADVMCATGDPVHSTPYLLAKKAGQSLQMEFLYHNKFSDFPQHDIHSEGVLSQESSQSTFLCDFLYQAPSAASKLSSEKKLLEETNKKWCVLEGGFLSYYENDKSTTPNGTININEVICLAIHKEDFYLNTGPIFIFEIYLPSERVFLFGAETSQAQRKWTEAIAKHFVPLFAENLTEADYDLIGQLFYKDCHALDQWRKGWFAMDKSSLHFCLQMQEVQGDRMHLRRLQELTISTMVQNGEKLDVLLLVEKGRTLYIHGHTKLDFTVWHTAIEKAAGTDGNALQDQQLSKNDVPIIVNSCIAFVTQYGLGCKYIYQKNGDPLHISELLESFKKDARSFKLRAGKHQLEDVTAVLKSFLSDIDDALLTKELYPYWISALDTQDDKERIKKYGAFIRSLPGVNRATLAAIIEHLYRVQKCSEINHMNAHNLALVFSSCLFQTKGQTSEEVNVIEDLINNYVEIFEVKEDQVKQMDIENSFITKWKDTQVSQAGDLLIEVYVERKEPDCSIIIRISPVMEAEELTNDILAIKNIIPTKGDIWATFEVIENEELERPLHYKENVLEQVLRWSSLAEPGSAYLVVKRFLTADTIKHCSDRSTLGSIKEGILKIKEEPSKILSGNKFQDRYFVLRDGFLFLYKDVKSSKHDKMFSLSSMKFYRGVKKKMKPPTSWGLTAYSEKHHWHLCCDSSRTQTEWMTSIFIAQHEYDIWPPAGKERKRSITKNPKIGGLPLIPIQHEGNATLARKNIESARAELERLRLSEKCDKESVDSSLKERASMVAHCLEHKDDKLRNRPRKHRSFNCLEDTEPEAPLGQPKGHKGLKTLRKTEDRNSKATLDSDHKLPSRVIEELNVVLQRSRTLPKELQDEQILK", "length": 1704 }, "evidence": [ { "id": "A0A8V0YPJ3", "url": "https://omabrowser.org/oma/group/A0A8V0YPJ3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPJ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPJ3" } ], "pmid": "" }, { "name": "phosphatidylinositol-3,4,5-trisphosphate binding", "id": "GO:0005547", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005547", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPJ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPJ3" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPJ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPJ3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPJ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPJ3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPJ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPJ3" } ], "pmid": "" }, { "name": "regulation of actin cytoskeleton organization", "id": "GO:0032956", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032956", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPJ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPJ3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 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} ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LRP12", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ02", "locus": { "chromosome": "2", "start_pos": 129575775, "end_pos": 129628302, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013041", "url": "https://www.ensembl.org/id/ENSGALG00010013041" } ] } } ], "crossref": [ { "id": "A0A8V0YQ02", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YQ02", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000033630", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000033630", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00041", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00041", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd00112", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00112", "database": "CDD", "categories": [ 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"categories": [ "Protein Classification", "Other" ] }, { "id": "PF00431", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00431", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A1D5PIZ5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PIZ5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PIZ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PIZ5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PL81", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PL81", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PL81-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PL81-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YBS8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBS8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YBS8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBS8-1", "database": "UniProtKB", 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receptor-related protein 12 OS=Gallus gallus OX=9031 GN=LRP12 PE=3 SV=1 CANONICAL=A0A8V0YQ02-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PIZ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ02/entry#A0A1D5PIZ5-1", "sequence": { "sequence": "MTKSTCGDIPEQIRSPSGTITSPGWPSEYPARINCSWYIHANPGEIITISFQDFDVQGSRRCSSDWLTIGSYKNIEGYRACGSSIPSPYISSQDHVWIRFHSDDSISRKGFRLAYFAGKSDEPNCDCDQFHCANGKCIPESWKCNNMDECGDNSDEEICAKANPPTISSFQPCASNQFQCLSRFTKLYTCLPESLKCDGNIDCLDLGDEIDCEVPTCGQWLKYFYGTFSSPNYPDFYPPGSNCTWLIDTGDHRKVILRFTDFKLDGTGFGDYVKIYDGLEENPRRLLRVLTAFDSHAPLTVVSSSGQIRVHFCADKVNAARGFNATYQVDGFCLPWEIPCGGNWGCYTEQQRCDGYWHCPNGRDETNCTMCQRDEFPCSRNGVCYPRSDRCNYQNHCPNGSDEKNCFFCQPGNFHCKNNRCVFESWVCDSQDDCGDGSDEENCPVIVPTRVITAAVIGSLICGLLLVIALGCTCKLYSLRMFERRSFETHLSRVEAELLRREAPPSYGQLIAQGLIPPVEDFPVCSPNQASVLENLRLAVRSQLGFTSIRLPITGRSSNIWNRIFNFARSRHSGSLALVSADGDDVASQSTSRDAERSNTHRSLFSVESDDTDTENERRDTAGAVGGVAATLPQKVPPATAIEATVGACGSSSAQSGSGGNTDSGREVTSIEPPGTSPARHQLTSALSRMTQGLRWVRFTLGRSSSVNQNQSPLRQLDNGVSGREEDDDVEMLIPVSDVASDFDMNDCSRPLLDLSSDQEPGLRQPYSATHHGVRSCNRDGPCESCGIVHTAQIPDTCLEATVKNETSDDEALLLC", "length": 816, "header": "tr|A0A1D5PIZ5-1|A0A1D5PIZ5_CHICK Computationally mapped isoform of Low-density lipoprotein receptor-related protein 12 OS=Gallus gallus OX=9031 GN=LRP12 PE=3 SV=2 CANONICAL=A0A8V0YQ02-1" }, "locus": { "chromosome": "2", "start_pos": 129594160, "end_pos": 129578136, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031260.1", "url": "https://www.ensembl.org/id/ENSGALT00010031260.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018218.1", "url": "https://www.ensembl.org/id/ENSGALP00010018218.1" } ] } }, { "isoform_ac": "A0A1D5PL81-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ02/entry#A0A1D5PL81-1", "sequence": { "sequence": "MAPWGSAEGFPAWRSAQLLLLVVSCCGNGALAEHSENVHISGVSTACGDIPEQIRSPSGTITSPGWPSEYPARINCSWYIHANPGEIITISFQDFDVQGSRRCSSDWLTIGSYKNIEGYRACGSSIPSPYISSQDHVWIRFHSDDSISRKGFRLAYFAGKSDEPNCDCDQFHCANGKCIPESWKCNNMDECGDNSDEEICAKANPPTISSFQPCASNQFQCLSRFTKLYTCLPESLKCDGNIDCLDLGDEIDCEVPTCGQWLKYFYGTFSSPNYPDFYPPGSNCTWLIDTGDHRKVILRFTDFKLDGTGFGDYVKIYDGLEENPRRLLRVLTAFDSHAPLTVVSSSGQIRVHFCADKVNAARGFNATYQVDGFCLPWEIPCGGNWGCYTEQQRCDGYWHCPNGRDETNCTMCQRDEFPCSRNGVCYPRSDRCNYQNHCPNGSDEKNCFFCQPGNFHCKNNRCVFESWVCDSQDDCGDGSDEENCPVIVPTRVITAAVIGSLICGLLLVIALGCTCKLYSLRMFERRSFETHLSRVEAELLRREAPPSYGQLIAQGLIPPVEDFPVCSPNQASVLENLRLAVRSQLGFTSIRLPITGRSSNIWNRIFNFARSRHSGSLALVSADGDDVASQSTSRDAERSNTHRSLFSVESDDTDTENERRDTAGAVGGVAATLPQKVPPATAIEATVGACGSSSAQSGSGGNTDSGREVTSIEPPGTSPARHQLTSALSRMTQGLRWVRFTLGRSSSVNQNQSPLRQLDNGVSGREEDDDVEMLIPVSDVASDFDMNDCSRPLLDLSSDQEPGLRQPYSATHHGVRSCNRDGPCESCGIVHTAQIPDTCLEATVKNETSDDEALLLC", "length": 857, "header": "tr|A0A1D5PL81-1|A0A1D5PL81_CHICK Computationally mapped isoform of Low-density lipoprotein receptor-related protein 12 OS=Gallus gallus OX=9031 GN=LRP12 PE=3 SV=3 CANONICAL=A0A8V0YQ02-1" }, "locus": { "chromosome": "2", "start_pos": 129628103, "end_pos": 129578136, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031267.1", "url": "https://www.ensembl.org/id/ENSGALT00010031267.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018223.1", "url": "https://www.ensembl.org/id/ENSGALP00010018223.1" } ] } }, { "isoform_ac": "A0A8V0YBS8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ02/entry#A0A8V0YBS8-1", "sequence": { "sequence": "MVLLQNILKMCIFQECQRLLSVSFGGNKGTDVVTCGDIPEQIRSPSGTITSPGWPSEYPARINCSWYIHANPGEIITISFQDFDVQGSRRCSSDWLTIGSYKNIEGYRACGSSIPSPYISSQDHVWIRFHSDDSISRKGFRLAYFAGKSDEPNCDCDQFHCANGKCIPESWKCNNMDECGDNSDEEICAKANPPTISSFQPCASNQFQCLSRFTKLYTCLPESLKCDGNIDCLDLGDEIDCEVPTCGQWLKYFYGTFSSPNYPDFYPPGSNCTWLIDTGDHRKVILRFTDFKLDGTGFGDYVKIYDGLEENPRRLLRVLTAFDSHAPLTVVSSSGQIRVHFCADKVNAARGFNATYQVDGFCLPWEIPCGGNWGCYTEQQRCDGYWHCPNGRDETNCTMCQRDEFPCSRNGVCYPRSDRCNYQNHCPNGSDEKNCFFCQPGNFHCKNNRCVFESWVCDSQDDCGDGSDEENCPVIVPTRVITAAVIGSLICGLLLVIALGCTCKLYSLRMFERRSFETHLSRVEAELLRREAPPSYGQLIAQGLIPPVEDFPVCSPNQASVLENLRLAVRSQLGFTSIRLPITGRSSNIWNRIFNFARSRHSGSLALVSADGDDVASQSTSRDAERSNTHRSLFSVESDDTDTENERRDTAGAVGGVAATLPQKVPPATAIEATVGACGSSSAQSGSGGNTDSGREVTSIEPPGTSPARHQLTSALSRMTQGLRWVRFTLGRSSSVNQNQSPLRQLDNGVSGREEDDDVEMLIPVSDVASDFDMNDCSRPLLDLSSDQEPGLRQPYSATHHGVRSCNRDGPCESCGIVHTAQIPDTCLEATVKNETSDDEALLLC", "length": 845, "header": "tr|A0A8V0YBS8-1|A0A8V0YBS8_CHICK Computationally mapped isoform of Low-density lipoprotein receptor-related protein 12 OS=Gallus gallus OX=9031 GN=LRP12 PE=3 SV=1 CANONICAL=A0A8V0YQ02-1" }, "locus": { "chromosome": "2", "start_pos": 129598921, "end_pos": 129578136, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031261.1", "url": "https://www.ensembl.org/id/ENSGALT00010031261.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018219.1", "url": "https://www.ensembl.org/id/ENSGALP00010018219.1" } ] } }, { "isoform_ac": "A0A8V0YI61-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ02/entry#A0A8V0YI61-1", "sequence": { "sequence": "MAPWGSAEGFPAWRSAQLLLLVVSCCACGDIPEQIRSPSGTITSPGWPSEYPARINCSWYIHANPGEIITISFQDFDVQGSRRCSSDWLTIGSYKNIEGYRACGSSIPSPYISSQDHVWIRFHSDDSISRKGFRLAYFAGKSDEPNCDCDQFHCANGKCIPESWKCNNMDECGDNSDEEICAKANPPTISSFQPCASNQFQCLSRFTKLYTCLPESLKCDGNIDCLDLGDEIDCEVPTCGQWLKYFYGTFSSPNYPDFYPPGSNCTWLIDTGDHRKVILRFTDFKLDGTGFGDYVKIYDGLEENPRRLLRVLTAFDSHAPLTVVSSSGQIRVHFCADKVNAARGFNATYQVDGFCLPWEIPCGGNWGCYTEQQRCDGYWHCPNGRDETNCTMCQRDEFPCSRNGVCYPRSDRCNYQNHCPNGSDEKNCFFCQPGNFHCKNNRCVFESWVCDSQDDCGDGSDEENCPVIVPTRVITAAVIGSLICGLLLVIALGCTCKLYSLRMFERRSFETHLSRVEAELLRREAPPSYGQLIAQGLIPPVEDFPVCSPNQASVLENLRLAVRSQLGFTSIRLPITGRSSNIWNRIFNFARSRHSGSLALVSADGDDVASQSTSRDAERSNTHRSLFSVESDDTDTENERRDTAGAVGGVAATLPQKVPPATAIEATVGACGSSSAQSGSGGNTDSGREVTSIEPPGTSPARHQLTSALSRMTQGLRWVRFTLGRSSSVNQNQSPLRQLDNGVSGREEDDDVEMLIPVSDVASDFDMNDCSRPLLDLSSDQEPGLRQPYSATHHGVRSCNRDGPCESCGIVHTAQIPDTCLEATVKNETSDDEALLLC", "length": 838, "header": "tr|A0A8V0YI61-1|A0A8V0YQ02_CHICK Computationally mapped isoform of Low-density lipoprotein receptor-related protein 12 OS=Gallus gallus OX=9031 GN=LRP12 PE=3 SV=1 CANONICAL=A0A8V0YQ02-1" }, "locus": { "chromosome": "2", "start_pos": 129628103, "end_pos": 129578136, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031263.1", "url": "https://www.ensembl.org/id/ENSGALT00010031263.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018221.1", "url": "https://www.ensembl.org/id/ENSGALP00010018221.1" } ] } }, { "isoform_ac": "A0A8V0YQ02-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ02/entry#A0A8V0YQ02-1", "sequence": { "sequence": "MAPWGSAEGFPAWRSAQLLLLVVSCCGNSLHSIQLHNYSGCSWNVLQLILIYSCYLCEGRVEGNGALAEHSENVHISGVSTACGDIPEQIRSPSGTITSPGWPSEYPARINCSWYIHANPGEIITISFQDFDVQGSRRCSSDWLTIGSYKNIEGYRACGSSIPSPYISSQDHVWIRFHSDDSISRKGFRLAYFAGKSDEPNCDCDQFHCANGKCIPESWKCNNMDECGDNSDEEICAKANPPTISSFQPCASNQFQCLSRFTKLYTCLPESLKCDGNIDCLDLGDEIDCEVPTCGQWLKYFYGTFSSPNYPDFYPPGSNCTWLIDTGDHRKVILRFTDFKLDGTGFGDYVKIYDGLEENPRRLLRVLTAFDSHAPLTVVSSSGQIRVHFCADKVNAARGFNATYQVDGFCLPWEIPCGGNWGCYTEQQRCDGYWHCPNGRDETNCTMCQRDEFPCSRNGVCYPRSDRCNYQNHCPNGSDEKNCFFCQPGNFHCKNNRCVFESWVCDSQDDCGDGSDEENCPVIVPTRVITAAVIGSLICGLLLVIALGCTCKLYSLRMFERRSFETHLSRVEAELLRREAPPSYGQLIAQGLIPPVEDFPVCSPNQASVLENLRLAVRSQLGFTSIRLPITGRSSNIWNRIFNFARSRHSGSLALVSADGDDVASQSTSRDAERSNTHRSLFSVESDDTDTENERRDTAGAVGGVAATLPQKVPPATAIEATVGACGSSSAQSGSGGNTDSGREVTSIEPPGTSPARHQLTSALSRMTQGLRWVRFTLGRSSSVNQNQSPLRQLDNGVSGREEDDDVEMLIPVSDVASDFDMNDCSRPLLDLSSDQEPGLRQPYSATHHGVRSCNRDGPCESCGIVHTAQIPDTCLEATVKNETSDDEALLLC", "length": 893, "header": "tr|A0A8V0YQ02-1|A0A8V0YQ02_CHICK Isoform 1 of Low-density lipoprotein receptor-related protein 12 OS=Gallus gallus OX=9031 GN=LRP12 PE=3 SV=1 CANONICAL=A0A8V0YQ02-1" }, "locus": { "chromosome": "2", "start_pos": 129628103, "end_pos": 129578136, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031262.1", "url": "https://www.ensembl.org/id/ENSGALT00010031262.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018220.1", "url": "https://www.ensembl.org/id/ENSGALP00010018220.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:420267", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420267", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3Q1LUU5-1", "protein_name": "Low-density lipoprotein receptor-related protein 12", "gene_name": "LRP12", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MARRWNTKESPRWRSALVLLFLAGVYACGETPEQIRAPSGIITSPGWPSEYPARINCSWFIRANPGEIITISFQDFDIQGSRRCSLDWLTIETYKNIESYRACGSTIPPPYISSQDHVWIRFHSDDSISRKGFRLAYFSGKSEEPNCACDQFRCGNGKCIPAAWKCNNMDECGDSSDEEICAREANPPTSASFQPCAYNQFQCLSRFTKVYTCLPESLKCDGNIDCLDLGDEIDCDVPTCGQWLKYFYGTFNSPNYPDFYPPGSNCTWLIDTGDHRKVILRFTDFKLDGTGYGDYVKIYDGLEENPHKLLRVLTAFDSHAPLTVVSSSGQIRVHFCADKVNAARGFNATYQVDGFCLPWEIPCGGNWGCYTEQQRCDGYWHCPNGRDEINCTVCQKEEFPCSRNGVCYPRSDRCNYQNHCPNGSDEKNCFFCQPGNFHCKNNRCVFESWVCDSQDDCGDGSDEENCPVIVPTRVITAAVIGSLICGLLLVIALGCTCKLYSLRMFERRSFETQLSRVEAELLRREAPPSYGQLIAQGLIPPVEDFPVCSPNQASVLENLRLAVRSQLGFTSIRLPMAGRSSNIWNRIFNFARSRHSGSLALVSADGDEVVPSQSTSREPERNHTHRSLFSVESDDTDTENERRDTAGASGGVTAPLPQKVPPTTAVEATVGASGSSSTQSTRGGHTETGRDVTSVEPPSVSPARHQLTSALSRMTQGLRWVRFTLGRSSSSNQNQSPLRQLDNGVNGREEDDDVEMLIPVSEGASDFDVNDCSRPLLDLASDQGQGFRQPYSGTNPGVRPSSRDGPCERCGIVHTAQIPDSCLEATLKTETSDDEALLLC", "length": 840 }, "evidence": [ { "id": "A0A8V0YQ02", "url": "https://omabrowser.org/oma/group/A0A8V0YQ02/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "D3ZCF7-1", "protein_name": "Low-density lipoprotein receptor-related protein 12", "gene_name": "Lrp12", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MARRWSTKESPRRGSAWLLLFLAGVYGNGALAELSENVHISGVSTACGETPEQIRGPTGIITSPGWPSDYPAKINCSWLIRANPGEIITISFQDFDIQGSRRCTLDWLTIETYKNIESYRACGSTIPPPYISSQDHVWIRFHSDDSVSRKGFRLAYFSGKSEEPHCACDQFRCGNGKCIPEAWKCNSMDECGDSSDEEVCVQDAHPPTTTAFQPCAYNQFQCLSRFTKVYTCLPESLKCDGNIDCLDLGDEIDCDMPTCGQWLKYFYGTFSSPNYPDFYPPGSNCTWLIDTGDHRKVILRFTDFKLDGTGYGDYVKIYDGLEENPRKLLRVLTAFDSHAPLTVVSSSGQIRVHFCADKVNAARGFNATYQVDGFCLPWEIPCGGNWGCYTEQQRCDGYWHCPNGRDEINCTMCQKEEFPCSRNGVCYPRSDRCNYQNHCPNGSDEKNCFFCQPGNFHCKNNRCVFESWVCDSQDDCGDGSDEESCPVIVPTRVITAAVIGSLVCGLLLVIALGCTCKLYSLRMFERRSFETQLSRVEAELLRREAPPSYGQLIAQGLIPPVEDFPVCSPNQASVLENLRLAVRSQLGFPSIRLPMTGRSRNIWNRIFNFARSRHSGSLALVSGDGDEVVPSQSSSRETERSHPHRSLFSAESDDTDTENERRDTAGASGGVAAPLPQKVPPTTAVEATVGTGGNSSAQSTRGGHADGREVSSVEAPSVSPARHQLTSALSRMTQGLRWVRFTLGRSSSTNQNRSPLRQLDTGVSGREDDDDVEMLIPVSDGASDIDANECSRPLLDLASDQVQGFRQPHSSGNPGARTSNRDGPCERCGIVHTAQIPDTCLEAAVKTEACDDEALLLC", "length": 858 }, "evidence": [ { "id": "A0A8V0YQ02", "url": "https://omabrowser.org/oma/group/A0A8V0YQ02/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8BUJ9-1", "protein_name": "Low-density lipoprotein receptor-related protein 12", "gene_name": "Lrp12", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MARRWSTKESQRRGSAWLLLFLAGVYGNGALAELSENVHISGVSTACGESPEQIRAPSGIITSPGWPSDYPAQVNCSWLIRANPGEIITISFQDFDIQGSRRCTLDWLTIETYKNIESYRACGSTIPPPYISSQDHVWIRFHSDDSVSRKGFRLAYFSGKSEQPDCACDQFRCGNGKCIPEAWKCNSMDECGDSSDEEVCASDAHPPTTTAFQPCAYNQFQCLSRFTKVYTCLPESLKCDGNIDCLDLGDEIDCDMPTCGQWLKYFYGTFNSPNYPDFYPPGSNCTWLIDTGDHRKVILRFTDFKLDGTGYGDYVKIYDGLEENPRKLLRVLTAFDSHAPLTVVSSSGQIRVHFCADKVNAARGFNATYQVDGFCLPWEIPCGGNWGCYTEQQRCDGYWHCPNGRDEINCTMCQKEEFPCSRNGVCYPRSDRCNYQNHCPNGSDEKNCFFCQPGNFHCKNNRCVFESWVCDSQDDCGDGSDEENCPVIVPTRVITAAVIGSLICGLLLVIALGCTCKLYSLRMFERRSFETQLSRVEAELLRREAPPSYGQLIAQGLIPPVEDFPVCSPNQASVLENLRLAVRSQLGFTSIRLPMTGRSSNIWNRIFNFARSRHSGSLALVSGDGDEVVPSQSSSRETERSRPHRSLFSVESDDTDTENERRDTAGASGGVAAPLPQKVPPTTAVEATVGSGGNSSAQSTRGGHADGREVSSVEAPSVSPARHQLTSALSRMTQGLRWVRFTLGRSSSTTQNRSPLRQLDTAVSGREDDDDVEMLIPVSDGASDIDANDCSRPLLDLASDQVQGFRQPHSAGNPGVRTSNRDGPCERCGIVHTAQIPDTCLEATVKTETSDDEALLLC", "length": 858 }, "evidence": [ { "id": "A0A8V0YQ02", "url": "https://omabrowser.org/oma/group/A0A8V0YQ02/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9Y561-1", "protein_name": "Low-density lipoprotein receptor-related protein 12", "gene_name": "LRP12", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MACRWSTKESPRWRSALLLLFLAGVYGNGALAEHSENVHISGVSTACGETPEQIRAPSGIITSPGWPSEYPAKINCSWFIRANPGEIITISFQDFDIQGSRRCNLDWLTIETYKNIESYRACGSTIPPPYISSQDHIWIRFHSDDNISRKGFRLAYFSGKSEEPNCACDQFRCGNGKCIPEAWKCNNMDECGDSSDEEICAKEANPPTAAAFQPCAYNQFQCLSRFTKVYTCLPESLKCDGNIDCLDLGDEIDCDVPTCGQWLKYFYGTFNSPNYPDFYPPGSNCTWLIDTGDHRKVILRFTDFKLDGTGYGDYVKIYDGLEENPHKLLRVLTAFDSHAPLTVVSSSGQIRVHFCADKVNAARGFNATYQVDGFCLPWEIPCGGNWGCYTEQQRCDGYWHCPNGRDETNCTMCQKEEFPCSRNGVCYPRSDRCNYQNHCPNGSDEKNCFFCQPGNFHCKNNRCVFESWVCDSQDDCGDGSDEENCPVIVPTRVITAAVIGSLICGLLLVIALGCTCKLYSLRMFERRSFETQLSRVEAELLRREAPPSYGQLIAQGLIPPVEDFPVCSPNQASVLENLRLAVRSQLGFTSVRLPMAGRSSNIWNRIFNFARSRHSGSLALVSADGDEVVPSQSTSREPERNHTHRSLFSVESDDTDTENERRDMAGASGGVAAPLPQKVPPTTAVEATVGACASSSTQSTRGGHADNGRDVTSVEPPSVSPARHQLTSALSRMTQGLRWVRFTLGRSSSLSQNQSPLRQLDNGVSGREDDDDVEMLIPISDGSSDFDVNDCSRPLLDLASDQGQGLRQPYNATNPGVRPSNRDGPCERCGIVHTAQIPDTCLEVTLKNETSDDEALLLC", "length": 859 }, "evidence": [ { "id": "A0A8V0YQ02", "url": "https://omabrowser.org/oma/group/A0A8V0YQ02/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "clathrin-coated pit", "id": "GO:0005905", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005905", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQ02", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ02" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQ02", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ02" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "endocytosis", "id": "GO:0006897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006897", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQ02", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ02" } ], "pmid": "" }, { "name": "neuron projection development", "id": "GO:0031175", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031175", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQ02", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ02" } ], "pmid": "" }, { "name": "neuron migration", "id": "GO:0001764", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001764", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQ02", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ02" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "integrin binding", "id": "GO:0005178", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005178", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQ02", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ02" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 111, "end_pos": 113, "annotation": "n_glycosylation_sequon" }, { "start_pos": 319, "end_pos": 321, "annotation": "n_glycosylation_sequon" }, { "start_pos": 37, "end_pos": 39, "annotation": "n_glycosylation_sequon" }, { "start_pos": 401, "end_pos": 403, "annotation": "n_glycosylation_sequon" }, { "start_pos": 444, "end_pos": 446, "annotation": "n_glycosylation_sequon" }, { "start_pos": 476, "end_pos": 478, "annotation": "n_glycosylation_sequon" }, { "start_pos": 787, "end_pos": 789, "annotation": "n_glycosylation_sequon" }, { "start_pos": 882, "end_pos": 884, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YQ02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ02" }, { "id": "PS01180", "database": "PROSITE", "url": "https://prosite.expasy.org/PS01180" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CUB", "eco_id": "ECO_0000259", "start_pos": 83, "end_pos": 195, "start_aa": "Cys", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 111, "end_pos": 113 }, { "start_pos": 319, "end_pos": 321 }, { "start_pos": 37, "end_pos": 39 }, { "start_pos": 401, "end_pos": 403 }, { "start_pos": 444, "end_pos": 446 }, { "start_pos": 476, "end_pos": 478 }, { "start_pos": 787, "end_pos": 789 }, { "start_pos": 882, "end_pos": 884 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": 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"id": "ENSGALG00010013045", "url": "https://www.ensembl.org/id/ENSGALG00010013045" } ] } } ], "crossref": [ { "id": "A0A8V0YQ12", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YQ12", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00063", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00063", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd12901", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12901", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "427302", "url": "https://www.ncbi.nlm.nih.gov/gene/427302", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001870", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001870", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003649", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003649", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003877", 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[ "Protein Classification" ] }, { "id": "A0A8V0YQ17", "url": "https://www.orthodb.org/?gene=A0A8V0YQ17", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24099", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24099", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24099:SF8", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24099:SF8", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00041", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00041", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00622", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00622", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YI66", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI66", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YI66-1", "url": 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"database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQ17-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ17-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MCLARSWVSKYGPVRKVLTQPFGLWAFGLLCFPVPGSCFVSSVLCGLRCSWPTSFGLGIFVIFPIFNYFCAGASYSPVLQKETLQRIISTLASKNDEIHNFIDMLNQTIQNVQINSSNVISELDDEFDALYSVLDEMRGSMASTIQQEQARKIQALQNQLSNCSNALESSEELLELAAQSLDIKDPVKFSEAARQIKDRVTMASAFRISLKPEVSDSMTHLMVDFTRERHALQTVKFLPVPKAPIIDLAACLVIDNCITVSWRMPEEDSRVDHFVLEYRKTNFDGLARVKDEQSWELIDYIKATEYTLSGLKFDTKYINVRVRACNKAVAGEYSDPVTLETKAFVFDLDNTSSHVNLKVEDSYVEWEPTGGRGQEKVKGKENKSRSGASPKRTSIGGKAPVKGSRDRFAGESYTVLGNNAIESGQHYWEVRAQKDCKSYSVGVAYKTLGKYDQLGKTNISWCIHVNNWLQNTLAAKHNNKTKTLDMPVPDRLGVYCNFDGGQLTFYNAISKVPLYTFRMKFTQPLLPAFMIRCGGLAVSTGLQVPSAVKTLQKNENGLSGSTGSLNNIAQ", "length": 570, "header": "tr|A0A8V0YQ12-1|A0A8V0YQ12_CHICK Isoform 1 of Fibronectin type III and SPRY domain containing 1 like OS=Gallus gallus OX=9031 GN=FSD1L PE=4 SV=1 CANONICAL=A0A8V0YQ12-1" }, 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"MEEQRETLQRIISTLASKNDEIHNFIDMLNQTIQNVQINSSNVISELDDEFDALYSVLDEMRGSMASTIQQEQARKIQALQNQLSNCSNALESSEELLELAAQSLDIKDPVKFSEAARQIKDRVTMASAFRISLKPEVSDSMTHLMVDFTRERHALQTVKFLPVPKAPIIDLAACLVIDNCITVSWRMPEEDSRVDHFVLEYRKTNFDGLARVKDEQSWELIDYIKATEYTLSGLKFDTKYINVRVRACNKAVAGEYSDPVTLETKAFVFDLDNTSSHVNLKVEDSYVEWEPTGGRGQEKVKGKENKSRSGASPKRTSIGGKAPVKGSRDRFAGESYTVLGNNAIESGQHYWEVRAQKDCKSYSVGVAYKTLGKYDQLGKTNISWCIHVNNWLQNTLAAKHNNKTKTLDMPVPDRLGVYCNFDGGQLTFYNAISKVPLYTFRMKFTQPLLPAFMIRCGGLAVSTGLQVPSAVKTLQKNENGLSGSTGSLNNIAQ", "length": 494, "header": "tr|A0A8V0YI80-1|A0A8V0YQ12_CHICK Computationally mapped isoform of Fibronectin type III and SPRY domain containing 1 like OS=Gallus gallus OX=9031 GN=FSD1L PE=4 SV=1 CANONICAL=A0A8V0YQ12-1" }, "locus": { "chromosome": "Z", "start_pos": 55725020, "end_pos": 55696697, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031295.1", "url": "https://www.ensembl.org/id/ENSGALT00010031295.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018242.1", "url": "https://www.ensembl.org/id/ENSGALP00010018242.1" } ] } }, { "isoform_ac": "A0A8V0YK64-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ12/entry#A0A8V0YK64-1", "sequence": { "sequence": "MEEQRETLQRIISTLASKNDEIHNFIDMLNQTIQNVQINSSNVISELDDEFDALYSVLDEMRGSMASTIQQEQARKIQALQNQLSNCSNALESSEELLELAAQSLDIKDPVKFSENFMKAMELIFIV", "length": 127, "header": "tr|A0A8V0YK64-1|A0A8V0YQ12_CHICK Computationally mapped isoform of Fibronectin type III and SPRY domain containing 1 like OS=Gallus gallus OX=9031 GN=FSD1L PE=4 SV=1 CANONICAL=A0A8V0YQ12-1" }, "locus": { "chromosome": "Z", "start_pos": 55706357, "end_pos": 55696697, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031266.1", "url": "https://www.ensembl.org/id/ENSGALT00010031266.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018222.1", "url": "https://www.ensembl.org/id/ENSGALP00010018222.1" } ] } }, { "isoform_ac": "A0A8V0YQ12-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ12/entry#A0A8V0YQ12-1", "sequence": { "sequence": "MCLARSWVSKYGPVRKVLTQPFGLWAFGLLCFPVPGSCFVSSVLCGLRCSWPTSFGLGIFVIFPIFNYFCAGASYSPVLQKETLQRIISTLASKNDEIHNFIDMLNQTIQNVQINSSNVISELDDEFDALYSVLDEMRGSMASTIQQEQARKIQALQNQLSNCSNALESSEELLELAAQSLDIKDPVKFSEAARQIKDRVTMASAFRISLKPEVSDSMTHLMVDFTRERHALQTVKFLPVPKAPIIDLAACLVIDNCITVSWRMPEEDSRVDHFVLEYRKTNFDGLARVKDEQSWELIDYIKATEYTLSGLKFDTKYINVRVRACNKAVAGEYSDPVTLETKAFVFDLDNTSSHVNLKVEDSYVEWEPTGGRGQEKVKGKENKSRSGASPKRTSIGGKAPVKGSRDRFAGESYTVLGNNAIESGQHYWEVRAQKDCKSYSVGVAYKTLGKYDQLGKTNISWCIHVNNWLQNTLAAKHNNKTKTLDMPVPDRLGVYCNFDGGQLTFYNAISKVPLYTFRMKFTQPLLPAFMIRCGGLAVSTGLQVPSAVKTLQKNENGLSGSTGSLNNIAQ", "length": 570, "header": "tr|A0A8V0YQ12-1|A0A8V0YQ12_CHICK Isoform 1 of Fibronectin type III and SPRY domain containing 1 like OS=Gallus gallus OX=9031 GN=FSD1L PE=4 SV=1 CANONICAL=A0A8V0YQ12-1" }, "locus": { "chromosome": "Z", "start_pos": 55725020, "end_pos": 55696921, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031280.1", "url": "https://www.ensembl.org/id/ENSGALT00010031280.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018231.1", "url": "https://www.ensembl.org/id/ENSGALP00010018231.1" } ] } }, { "isoform_ac": "A0A8V0YQ17-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ12/entry#A0A8V0YQ17-1", "sequence": { "sequence": "MEEQRETLQRIISTLASKNDEIHNFIDMLNQTIQNVQINSSNVISELDDEFDALYSVLDEMRGSMASTIQQEQARKIQALQNQLSNCSNALESSEELLELAAQSLDIKDPVKFSEAARQIKDRVTMASAFRISLKPEVSDSMTHLMVDFTRERHALQTVKFLPVPKAPIIDLAACLVIDNCITVSWRMPEEDSRVDHFVLEYRKTNFDGLARVKDEQSWELIDYIKATEYTLSGLKFDTKYINVRVRACNKAVAGEYSDPVTLETKAFVFDLDNTSSHVNLKVEDSYVEWEPTGGRGQEKVKGKENKSSGQNTVLKSSKSGASPKRTSIGGKAPVKGSRDRFAGESYTVLGNNAIESGQHYWEVRAQKDCKSYSVGVAYKTLGKYDQLGKTNISWCIHVNNWLQNTLAAKHNNKTKTLDMPVPDRLGVYCNFDGGQLTFYNAISKVPLYTFRMKFTQPLLPAFMIRCGGLAVSTGLQVPSAVKTLQKNENGLSGSTGSLNNIAQ", "length": 504, "header": "tr|A0A8V0YQ17-1|A0A8V0YQ17_CHICK Computationally mapped isoform of Fibronectin type III and SPRY 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[ "Protein" ] }, { "id": "A0A8V0YFY4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFY4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YFY4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFY4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YGA2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGA2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YGA2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGA2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YI98", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI98", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YI98-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI98-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YII9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YII9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YII9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YII9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YIL4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIL4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YIL4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIL4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YIL9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIL9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YIL9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIL9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YNE5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNE5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YNE5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNE5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAECTPQPPSTWPASPQPHNTSAACPLEPMNMGVSEQQMPLEQPPSSPELGEDEEVTSPPDPDVPYPDLAPVVFFCLKQTTSPRSWCIKMCVSMMVILLNCVTLGMYQPCEDMDCLSDRCKILQVFDDFIFIFFAMEMVLKMVALGIFGKKCYLGDTWNRLDFFIVMAGMVEYSLDLQNINLSAIRTVRVLRPLKAINRVPSMRILVNLLLDTLPMLGNVLLLCFFVFFIFGIIGVQLWAGLLRNRCFMEENFTIQGDIVLPPYYQPEEDDEMPFICSLSGDNGIMGCHEIPPLKERGHECCLDKDDYYYYNSVRQEFNVSGMCVNWNQYYNVCRTGNANPHKGAINFDNIGYAWIVIFQVITLEGWVEIMYYVMDAHSFYNFIYFILLIIVGSFFMINLCLVVIATQFSETKQREHQLMQEQRARYLSSSTVASYMEPGDCYEEIFQYVCHIMRKAKRRTLGLYNSIQSRRQGHVEPSEAKRGASRKKQRHYSKDCTGESGNVNSGNRSLVGQQNDHRICQQHNPLDCPPQGLVQPIAVTATSDLTNCPRCHRGEHDTSRRLSVLDSADSDQEDGGDSEAEGEGCRGDHSASALEKEEEEVEEGGRMKLCSDMWREVRVKLRGIVDSKYFNRGIMIAILVNTISMGIEHHEQPEELTNILEISNVVFTSMFALEMILKLAAFGLFDYLRNPYNIFDSIIVIISIWEIIGQSDGGLSVLRTFRLLRVLKLVRFMPALRRQLVVLMKTMDNVATFCMLLMLFIFIFSILGMHIFGCKFSLRTDTGDTVPDRKNFDSLLWAIVTVFQILTQEDWNVVLYNGMASTSPWASLYFVALMTFGNYVLFNLLVAILVEGFQAEGDANRSYSEEDQSSSNMEELDQFQEIQEGSDPKLCAISVTPNGHLDPSLPSSNAPVAAGGVSNSSRNSLQPDQIRVAVGSRKSSVMSLGRMTYDQRSLSSSRSSHYGAWGRSGAWGSRRSSWNSLARGHSLKHKPPSAEHESLLSGDRHRVGDREPDGAERVFHHRRTLSLDNKGSCDLLELASIPSGHRGTCRPGTTSGGSEHQDCNGRMPSIAKEIFPKMNNRKERGEDDEEIDYSLCFRIRKMMEVYKPDWCELREDWSIYLFSPQNRFRLLCQTIIAHKLFDYVVLAFIFLNCITIALERPQIEHRSTERIFLTVSNYIFTAIFVAEMTLKVVSLGLYFGDQAYLRSSWNVLDGFLVFVSLIDIVVSVASAGGAKILGVLRVLRLLRTLRVISRAPGLKLVVETLISSLKPIGNIVLICCAFFIIFGILGVQLFKGKFYHCLGVDIRNITNRSDCVAANYKWVHHKYNFDNLGQALMSLFVLASKDGWVNIMYNGLDAVAVDQQPVTNNNPWMLLYFISFLLIVSFFVLNMFVGVVVENFHKCRQHQEAEEARRREEKRLRRLEKKRRKAQRLPYYATYCPIRLLIHSVCTSHYLDIFITFIICLNVVTMSLEHYNQPVSLETALKYCNYLFTTVFVLEAVLKLVAFGLRRFFKDRWNQLDLAIVLLSVMGITLEEIEINAALPINPTIIRIMRVLRIARVLKLLKMATGMRALLDTVVQALPQVGNLGLLFMLLFFIYAALGVELFGKLVCNDENPCEGMSRHATFENFGMAFLTLFQVSTGDNWNGIMKDTLRDCSHDDRSCLSNLQFISPLYFVSFVLTAQFVLINVVVAVLMKHLDDSNKEAQEDAEMDAEIELEFAHGLCSRKSGSSKSRQGKGAGSGSGGGRTEPEGRLCTRCYSPAQENLWLDSVSLIIKDSFDGELMIIDNLSGSVFHHYSSPAMCEKCNHDKQEVQLAEMEALSLNSDKSSSILLGDESDNRSTSQLSPKETKDGQDSPDSTEAGDVGECLLPISSTDGSTNPDNYLCEIEKTPFNSVQSWLKHEGTKVPPSPFSPGTSCPLLPVPAEFFHPAISATQTGPEKVSCAHNLPKISLQGSWASLRSPSVNCSLLHQAPESDTSLDSRSSSSAGSLQTTLEDSLNLSDSPQCALDLPVALCPMPAASDPRPLAAPLSPTSRRRSLRGRGLFTLRSIRRHQRSHSSGGSTSPGCTHHDSMDPSDEEGAGSSLRGGGNNSEPSETLSSLSLTSLFSPPPPGLTLGKKCSSTSSLHASPSPRRPAAHHTKPFYTVDPKGFLSMPSWVTDFCKDTPPPVQGAEPDGSSRLGTGECGSPLPSELELGDGVSKRNR", "length": 2207, "header": "tr|A0A8V0YNE5-1|A0A8V0YNE5_CHICK Isoform 1 of Calcium voltage-gated channel subunit alpha1 I OS=Gallus gallus OX=9031 GN=CACNA1I PE=4 SV=1 CANONICAL=A0A8V0YNE5-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YF54-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNE5/entry#A0A8V0YF54-1", "sequence": { "sequence": "MAECTPQPPSTWPASPQPHNTSAACPLEPMNMGVSEQQMPLEQPPSSPELGEDEEVTSPPDPDVPYPDLAPVVFFCLKQTTSPRSWCIKMCVSMMVILLNCVTLGMYQPCEDMDCLSDRCKILQVFDDFIFIFFAMEMVLKMVALGIFGKKCYLGDTWNRLDFFIVMAGMVEYSLDLQNINLSAIRTVRVLRPLKAINRVPSMRILVNLLLDTLPMLGNVLLLCFFVFFIFGIIGVQLWAGLLRNRCDIVLPPYYQPEEDDEMPFICSLSGDNGIMGCHEIPPLKERGHECCLDKDDYYYYNSVRQEFNVSGMCVNWNQYYNVCRTGNANPHKGAINFDNIGYAWIVIFQVITLEGWVEIMYYVMDAHSFYNFIYFILLIIVGSFFMINLCLVVIATQFSETKQREHQLMQEQRARYLSSSTVASYMEPGDCYEEIFQYVCHIMRKAKRRTLGLYNSIQSRRQGHVEPSEAKRGASRKKQRHYSKDCTGESGNVNSGNRSVTESISMCYISKGLCTMPSGDTASQCKAPSVQSFISPGICQQHNPLDCPPQGLVQPIAVTATSDLTNCPRCHRGEHDTSRRLSVLDSADSDQEDGGDSEAEGEGCRGDHSASALEKEEEEVEEGGRMKLCSDMWREVRVKLRGIVDSKYFNRGIMIAILVNTISMGIEHHEQPEELTNILEISNVVFTSMFALEMILKLAAFGLFDYLRNPYNIFDSIIVIISIWEIIGQSDGGLSVLRTFRLLRVLKLVRFMPALRRQLVVLMKTMDNVATFCMLLMLFIFIFSILGMHIFGCKFSLRTDTGDTVPDRKNFDSLLWAIVTVFQILTQEDWNVVLYNGMASTSPWASLYFVALMTFGNYVLFNLLVAILVEGFQAEVSHQRCYTCGEKEDRCLKLCAISVTPNGHLDPSLPSSNAPVAAGGVSNSSRNSLQPDQIRVAVGSRKSSVMSLGRMTYDQRSLSSSRSSHYGAWGRSGAWGSRRSSWNSLARGHSLKHKPPSAEHESLLSGDRHRVGDREPDGLASIPSGHRGTCRPGTTSGGSEHQDCNGRMPSIAKEIFPKMNNRKERGEDDEEIDYSLCFRIRKMMEVYKPDWCELREDWSIYLFSPQNRFRLLCQTIIAHKLFDYVVLAFIFLNCITIALERPQIEHRSTERIFLTVSNYIFTAIFVAEMTLKVVSLGLYFGDQAYLRSSWNVLDGFLVFVSLIDIVVSVASAGGAKILGVLRVLRLLRTLRVISRAPGLKLVVETLISSLKPIGNIVLICCAFFIIFGILGVQLFKGKFYHCLGVDIRNITNRSDCVAANYKWVHHKYNFDNLGQALMSLFVLASKDGWVNIMYNGLDAVAVDQQPVTNNNPWMLLYFISFLLIVSFFVLNMFVGVVVENFHKCRQHQEAEEARRREEKRLRRLEKKRRKAQRLPYYATYCPIRLLIHSVCTSHYLDIFITFIICLNVVTMSLEHYNQPVSLETALKYCNYLFTTVFVLEAVLKLVAFGLRRFFKDRWNQLDLAIVLLSVMGITLEEIEINAALPINPTIIRIMRVLRIARVLKLLKMATGMRALLDTVVQALPQVGNLGLLFMLLFFIYAALGVELFGKLVCNDENPCEGMSRHATFENFGMAFLTLFQVSTGDNWNGIMKDTLRDCSHDDRSCLSNLQFISPLYFVSFVLTAQFVLINVVVAVLMKHLDDSNKEAQEDAEMDAEIELEFAHGLCSRKSGSSKSRQGKGAGSGSGGGRTEPEGRLVSLIIKDSFDGELMIIDNLSGSVFHHYSSPAMCEKCNHDKQEVTRVRGCVRGLFPQDLHIHTHAPAGHPVCVPGCSLCRQRAWPVFVIYHVLLRLPLV", "length": 1835, "header": "tr|A0A8V0YF54-1|A0A8V0YF54_CHICK Computationally mapped isoform of Voltage-dependent T-type calcium channel subunit alpha OS=Gallus gallus OX=9031 GN=CACNA1I PE=3 SV=1 CANONICAL=A0A8V0YNE5-1" }, "locus": { "chromosome": "1", "start_pos": 50598740, "end_pos": 50459250, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030219.1", "url": "https://www.ensembl.org/id/ENSGALT00010030219.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017542.1", "url": "https://www.ensembl.org/id/ENSGALP00010017542.1" } ] } }, { "isoform_ac": "A0A8V0YFD7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNE5/entry#A0A8V0YFD7-1", "sequence": { "sequence": "MGGKPMRAEGGEMGSVLCVLVMNTASSAAGWLLLPYDVSEGSFTSPPDPDVPYPDLAPVVFFCLKQTTSPRSWCIKMCVSMMVILLNCVTLGMYQPCEDMDCLSDRCKILQVFDDFIFIFFAMEMVLKMVALGIFGKKCYLGDTWNRLDFFIVMAGMVEYSLDLQNINLSAIRTVRVLRPLKAINRVPSMRILVNLLLDTLPMLGNVLLLCFFVFFIFGIIGVQLWAGLLRNRCFMEENFTIQGDIVLPPYYQPEEDDEMPFICSLSGDNGIMGCHEIPPLKERGHECCLDKDDYYYYNSVRQEFNVSGMCVNWNQYYNVCRTGNANPHKGAINFDNIGYAWIVIFQVITLEGWVEIMYYVMDAHSFYNFIYFILLIIVGSFFMINLCLVVIATQFSETKQREHQLMQEQRARYLSSSTVASYMEPGDCYEEIFQYVCHIMRKAKRRTLGLYNSIQKGVQCIHNLASAFGHDSPHLSAKITRNKRLAHSRDANCIREFCSQAKKQAVRVDVVEVGSHEWLRSSLTAAKEFELDQKGDSVHFRALLVLTLNFPSPQPEELTNILEISNVVFTSMFALEMILKLAAFGLFDYLRNPYNIFDSIIVIISIWEIIGQSDGGLSVLRTFRLLRVLKLVRFMPALRRQLVVLMKTMDNVATFCMLLMLFIFIFSILGMHIFGCKFSLRTDTGDTVPDRKNFDSLLWAIVTVFQILTQEDWNVVLYNGMASTSPWASLYFVALMTFGNYVLFNLLVAILVEGFQAEVRNTRKSGLFYQFQEIQEGSGMIAQTISFAHIPLLLSGKSESRFGPLGGYLMSAARQHFPSPAESQPALLQSSSRSSHYGAWGRSGAWGSRRSSWNSLARGHSLKHKPPSAEHESLLSGDRHRVGDREPDGAERVFHHRRTLSLDNKGSCDLLELASIPSGHRGTCRPGTTSGGSEHQDCNGRMPSIAMRSQPVTLASSASLQSLCFRIRKMMEVYKPDWCELREDWSIYLFSPQNRFRLLCQTIIAHKLFDYVVLAFIFLNCITIALERPQIEHRSTERIFLTVSNYIFTAIFVAEMTLKVVSLGLYFGDQAYLRSSWNVLDGFLVFVSLIDIVVSVASAGGAKILGVLRVLRLLRTLRVISRAPGLKLVVETLISSLKPIGNIVLICCAFFIIFGILGVQLFKGKFYHCLGVDIRNITNRSDCVAANYKWVHHKYNFDNLGQALMSLFVLASKDGWVNIMYNGLDAVAVDQQPVTNNNPWMLLYFISFLLIVSFFVLNMFVGVVVENFHKCRQHQEAEEARRREEKRLRRLEKKRRSKAQPKCLVEAQRLPYYATYCPIRLLIHSVCTSHYLDIFITFIICLNVVTMSLEHYNQPVSLETALKYCNYLFTTVFVLEAVLKLVAFGLRRFFKDRWNQLDLAIVLLSVMGITLEEIEINAALPINPTIIRIMRVLRIARVLKLLKMATGMRALLDTVVQALPQVGNLGLLFMLLFFIYAALGVELFGKLVCNDENPCEGMSRHATFENFGMAFLTLFQVSTGDNWNGIMKDTLRDCSHDDRSCLSNLQFISPLYFVSFVLTAQFVLINVVVAVLMKHLDDSNKEAQEDAEMDAEIELEFAHGLCSRKSGSSKSRQGKGAGSGSGGGRTEPEGRLCTRCYSPAQVGIPLSLPTRLQQAAVGRSQGA", "length": 1664, "header": "tr|A0A8V0YFD7-1|A0A8V0YFD7_CHICK Computationally mapped isoform of Voltage-dependent T-type calcium channel subunit alpha OS=Gallus gallus OX=9031 GN=CACNA1I PE=3 SV=2 CANONICAL=A0A8V0YNE5-1" }, "locus": { "chromosome": "1", "start_pos": 50599780, "end_pos": 50460127, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030369.1", "url": "https://www.ensembl.org/id/ENSGALT00010030369.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017617.1", "url": "https://www.ensembl.org/id/ENSGALP00010017617.1" } ] } }, { "isoform_ac": "A0A8V0YFY4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNE5/entry#A0A8V0YFY4-1", "sequence": { "sequence": "MNHCQNEQGRIAQNEPWILREKSESVCVDYVRLWQQSGSSYQQLFPLIFLMMVILLNCVTLGMYQPCEDMDCLSDRCKILQVFDDFIFIFFAMEMVLKMVALGIFGKKCYLGDTWNRLDFFIVMAGMVEYSLDLQNINLSAIRTVRVLRPLKAINRVPSMRILVNLLLDTLPMLGNVLLLCFFVFFIFGIIGVQLWAGLLRNRCFMEENFTIQGDIVLPPYYQPEEDDEMPFICSLSGDNGIMGCHEIPPLKERGHECCLDKDDYYYYNSVRQEFNVSGMCVNWNQYYNVCRTGNANPHKGAINFDNIGYAWIVIFQVITLEGWVEIMYYVMDAHSFYNFIYFILLIIVGSFFMINLCLVVIATQFSETKQREHQLMQEQRARYLSSSTVASYMEPGDCYEEIFQYVCHIMRKAKRRTLGLYNSIQSRRQGHVEPSEAKRGASRKKQRHYSKDCTGESGNVNSGNRSVTESISMCYISKGLWSTKGEHDTSRRLSVLDSADSDQEDGGDSEAEGEGCRGDHSASALEKEEEEVEEGGRMKLCSDMWREVRVKLRGIVDSKYFNRGIMIAILVNTISMGIEHHEQPEELTNILEISNVVFTSMFALEMILKLAAFGLFDYLRNPYNIFDSIIVIISIWEIIGQSDGGLSVLRTFRLLRVLKLVRFMPALRRQLVVLMKTMDNVATFCMLLMLFIFIFSILGMHIFGCKFSLRTDTGDTVPDRKNFDSLLWAIVTVFQILTQEDWNVVLYNGMASTSPWASLYFVALMTFGNYVLFNLLVAILVEGFQAEVSHQRCYTLVFHRQVVLFFLETEKNISKSWVKKGAHGLGPLGGYLMSAARQHFPSPAESQPALLQSSSRSSHYGAWGRSGAWGSRRSSWNSLARGHSLKHKPPSAEHESLLSGDRHRVGDREPDGAERVFHHRRTLSLDNKGSCDLLELASIPSGHRGTCRPGTTSGGSEHQDCNGRISQPVTLASSASLQSLCFRIRKMMEVYKPDWCELREDWSIYLFSPQNRFRLLCQTIIAHKLFDYVVLAFIFLNCITIALERPQIEHRSTERIFLTVSNYIFTAIFVAEMTLKVVSLGLYFGDQAYLRSSWNVLDGFLVFVSLIDIVVSVASAGGAKILGVLRVLRLLRTLRVISRAPGLKLVVETLISSLKPIGNIVLICCAFFIIFGILGVQLFKGKFYHCLGVDIRNITNRSDCVAANYKWVHHKYNFDNLGQALMSLFVLASKDGWVNIMYNGLDAVAVDQQPVTNNNPWMLLYFISFLLIVSFFVLNMFVGVVVENFHKCRQHQEAEEARRREEKRLRRLEKKRRSKAQPKCLVEAQRLPYYATYCPIRLLIHSVCTSHYLDIFITFIICLNVVTMSLEHYNQPVSLETALKYCNYLFTTVFVLEAVLKLVAFGLRRFFKDRWNQLDLAIVLLSVMGITLEEIEINAALPINPTIIRIMRVLRIARVLKLLKMATGMRALLDTVVQALPQVGNLGLLFMLLFFIYAALGVELFGKLVCNDENPCEGMSRHATFENFGMAFLTLFQVSTGDNWNGIMKDTLRDCSHDDRSCLSNLQFISPLYFVSFVLTAQFVLINVVVAVLMKHLDDSNKEAQEDAEMDAEIELEFAHGLCSRKSGSSKSRQGKGAGSGSGGGRTEPEGRLVSLIIKDSFDGELMIIDNLSGSVFHHYSSPAMCEKCNHDKQEVTRVRGCVRGLFPQDLHIHTHAPAGHPVCVPGCSFTSLHQQQKVEKRALIGRYPHWKMTIFHLALDP", "length": 1759, "header": "tr|A0A8V0YFY4-1|A0A8V0YFY4_CHICK Computationally mapped isoform of Voltage-dependent T-type calcium channel subunit alpha OS=Gallus gallus OX=9031 GN=CACNA1I PE=3 SV=1 CANONICAL=A0A8V0YNE5-1" }, "locus": { "chromosome": "1", "start_pos": 50535521, "end_pos": 50458435, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030003.1", "url": "https://www.ensembl.org/id/ENSGALT00010030003.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017439.1", "url": "https://www.ensembl.org/id/ENSGALP00010017439.1" } ] } }, { "isoform_ac": "A0A8V0YGA2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNE5/entry#A0A8V0YGA2-1", "sequence": { "sequence": "MTSRSTISKQQMPLEQPPSSPELGEDEEVTSPPDPDVPYPDLAPVVFFCLKQTTSPRSWCIKMCVSMMVILLNCVTLGMYQPCEDMDCLSDRCKILQVFDDFIFIFFAMEMVLKMVALGIFGKKCYLGDTWNRLDFFIVMAGMVEYSLDLQNINLSAIRTVRVLRPLKAINRVPSMRILVNLLLDTLPMLGNVLLLCFFVFFIFGIIGVQLWAGLLRNRCFMEENFTIQGDIVLPPYYQPEEDDEMPFICSLSGDNGIMGCHEIPPLKERGHECCLDKDDYYYYNSVRQEFNVSGMCVNWNQYYNVCRTGNANPHKGAINFDNIGYAWIVIFQVITLEGWVEIMYYVMDAHSFYNFIYFILLIIVGSFFMINLCLVVIATQFSETKQREHQLMQEQRARYLSSSTVASYMEPGDCYEEIFQYVCHIMRKAKRRTLGLYNSIQSRRQGHVEPSEAKRGASRKKQRHYRICQQHNPLDCPPQGLVQPIAVTATSDLTNCPRCHRGEHDTSRRLSVLDSADSDQEDGGDSEAEGEGCRGDHSASALEKEEEEVEEGGRMKLCSDMWREVRVKLRGIVDSKYFNRGIMIAILVNTISMGIEHHEQPEELTNILEISNVVFTSMFALEMILKLAAFGLFDYLRNPYNIFDSIIVIISIWEIIGQSDGGLSVLRTFRLLRVLKLVRFMPALRRQLVVLMKTMDNVATFCMLLMLFIFIFSILGMHIFGCKFSLRTDTGDTVPDRKNFDSLLWAIVTVFQILTQEDWNVVLYNGMASTSPWASLYFVALMTFGNYVLFNLLVAILVEGFQAEGDANRSYSEEDQSSSNMEELDQFQEIQEGSDPKLCAISVTPNGHLDPSLPSSNAPVAAGGVSNSSRNSLQPDQIRVAVGSRKSSVMSLGRMTYDQRSLSSSRSSHYGAWGRSGAWGSRRSSWNSLARGHSLKHKPPSAEHESLLSGDRHRVGDREPDGAERVFHHRRTLSLDNKGSCDLLELASIPSGHRGTCRPGTTSGGSEHQDCNGRMPSIAKEIFPKMNNRKERGEDDEEIDYSLCFRIRKMMEVYKPDWCELREDWSIYLFSPQNRFRLLCQTIIAHKLFDYVVLAFIFLNCITIALERPQIEHRSTERIFLTVSNYIFTAIFVAEMTLKVVSLGLYFGDQAYLRSSWNVLDGFLVFVSLIDIVVSVASAGGAKILGVLRVLRLLRTLRVISRAPGLKLVVETLISSLKPIGNIVLICCAFFIIFGILGVQLFKGKFYHCLGVDIRNITNRSDCVAANYKWVHHKYNFDNLGQALMSLFVLASKDGWVNIMYNGLDAVAVDQQPVTNNNPWMLLYFISFLLIVSFFVLNMFVGVVVENFHKCRQHQEAEEARRREEKRLRRLEKKRRKAQRLPYYATYCPIRLLIHSVCTSHYLDIFITFIICLNVVTMSLEHYNQPVSLETALKYCNYLFTTVFVLEAVLKLVAFGLRRFFKDRWNQLDLAIVLLSVMGITLEEIEINAALPINPTIIRIMRVLRIARVLKLLKMATGMRALLDTVVQALPQVGNLGLLFMLLFFIYAALGVELFGKLVCNDENPCEGMSRHATFENFGMAFLTLFQVSTGDNWNGIMKDTLRDCSHDDRSCLSNLQFISPLYFVSFVLTAQFVLINVVVAVLMKHLDDSNKEAQEDAEMDAEIELEFAHGLCSRKSGSSKSRQGKGAGSGSGGGRTEPEGRLCTRCYSPAQENLWLDSVSLIIKDSFDGELMIIDNLSGSVFHHYSSPAMCEKCNHDKQEVTHVPWCWSGRTDRDVDEDNIVFSSARGAEVGAHGIQRTGRFTPQ", "length": 1807, "header": "tr|A0A8V0YGA2-1|A0A8V0YGA2_CHICK Computationally mapped isoform of Voltage-dependent T-type calcium channel subunit alpha OS=Gallus gallus OX=9031 GN=CACNA1I PE=3 SV=1 CANONICAL=A0A8V0YNE5-1" }, "locus": { "chromosome": "1", "start_pos": 50599276, "end_pos": 50459069, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030249.1", "url": "https://www.ensembl.org/id/ENSGALT00010030249.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017550.1", "url": "https://www.ensembl.org/id/ENSGALP00010017550.1" } ] } }, { "isoform_ac": "A0A8V0YI98-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNE5/entry#A0A8V0YI98-1", "sequence": { "sequence": "MAECTPQPPSTWPASPQPHNTSAACPLEPMNMGVSEQQMPLEQPPSSPELGEDEEVTSPPDPDVPYPDLAPVVFFCLKQTTSPRSWCIKMCVSMMVILLNCVTLGMYQPCEDMDCLSDRCKILQVFDDFIFIFFAMEMVLKMVALGIFGKKCYLGDTWNRLDFFIVMAGMVEYSLDLQNINLSAIRTVRVLRPLKAINRVPSMRILVNLLLDTLPMLGNVLLLCFFVFFIFGIIGVQLWAGLLRNRCDIVLPPYYQPEEDDEMPFICSLSGDNGIMGCHEIPPLKERGHECCLDKDDYYYYNSVRQEFNVSGMCVNWNQYYNVCRTGNANPHKGAINFDNIGYAWIVIFQVITLEGWVEIMYYVMDAHSFYNFIYFILLIIVGSFFMINLCLVVIATQFSETKQREHQLMQEQRARYLSSSTVASYMEPGDCYEEIFQYVCHIMRKAKRRTLGLYNSIQSRRQGHVEPSEAKRGASRKKQRHYSKDCTGESGNVNSGNRSVTESISMCYISKGLCRVSPEQWRQFLLMGHNPLDCPPQGLVQPIAVTATSDLTNCPRCHRGEHDTSRRLSVLDSADSDQEDGGDSEAEGEGCRGDHSASALEKEEEEVEEGGRMKLCSDMWREVRVKLRGIVDSKYFNRGIMIAILVNTISMGIEHHEQPEELTNILEISNVVFTSMFALEMILKLAAFGLFDYLRNPYNIFDSIIVIISIWEIIGQSDGGLSVLRTFRLLRVLKLVRFMPALRRQLVVLMKTMDNVATFCMLLMLFIFIFSILGMHIFGCKFSLRTDTGDTVPDRKNFDSLLWAIVTVFQILTQEDWNVVLYNGMASTSPWASLYFVALMTFGNYVLFNLLVAILVEGFQAEVSHQRCYTCGEKEDRCLKLCAISVTPNGHLDPSLPSSNAPVAAGGVSNSSRNSLQPDQIRVAVGSRKSSVMSLGRMTYDQRSLSSSRSSHYGAWGRSGAWGSRRSSWNSLARGHSLKHKPPSAEHESLLSGDRHRVGDREPDGAERVFHHRRTLSLDNKGSCDLLELASIPSDCNGRMPSIAKEIFPKMNNRKERGEDDEEIDYSLCFRIRKMMEVYKPDWCELREDWSIYLFSPQNRFRLLCQTIIAHKLFDYVVLAFIFLNCITIALERPQIEHRSTERIFLTVSNYIFTAIFVAEMTLKVVSLGLYFGDQAYLRSSWNVLDGFLVFVSLIDIVVSVASAGGAKILGVLRVLRLLRTLRVISRAPGLKLVVETLISSLKPIGNIVLICCAFFIIFGILGVQLFKGKFYHCLGVDIRNITNRSDCVAANYKWVHHKYNFDNLGQALMSLFVLASKDGWVNIMYNGLDAVAVDQQPVTNNNPWMLLYFISFLLIVSFFVLNMFVGVVVENFHKCRQHQEAEEARRREEKRLRRLEKKRRSKAQPKCLAQRLPYYATYCPIRLLIHSVCTSHYLDIFITFIICLNVVTMSLEHYNQPVSLETALKYCNYLFTTVFVLEAVLKLVAFGLRRFFKDRWNQLDLAIVLLSVMGITLEEIEINAALPINPTIIRIMRVLRIARVLKLLKMATGMRALLDTVVQALPQVGNLGLLFMLLFFIYAALGVELFGKLVCNDENPCEGMSRHATFENFGMAFLTLFQVSTGDNWNGIMKDTLRDCSHDDRSCLSNLQFISPLYFVSFVLTAQFVLINVVVAVLMKHLDDSNKEAQEDAEMDAEIELEFAHGLCSRKSGSSKSRQGKGAGSGSGGGRTEPEGRLCTRCYSPGWSRLAEAVTPAELKGRHKQCWAALTVSEDSPSFFFALDFGTFTHPKEQMLPL", "length": 1796, "header": "tr|A0A8V0YI98-1|A0A8V0YI98_CHICK Computationally mapped isoform of Voltage-dependent T-type calcium channel subunit alpha OS=Gallus gallus OX=9031 GN=CACNA1I PE=3 SV=1 CANONICAL=A0A8V0YNE5-1" }, "locus": { "chromosome": "1", "start_pos": 50598740, "end_pos": 50459714, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030184.1", "url": "https://www.ensembl.org/id/ENSGALT00010030184.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017526.1", "url": "https://www.ensembl.org/id/ENSGALP00010017526.1" } ] } }, { "isoform_ac": "A0A8V0YII9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNE5/entry#A0A8V0YII9-1", "sequence": { "sequence": "MAECTPQPPSTWPASPQPHNTSAACPLEPMNMGVSEQQMPLEQPPSSPELGEDEEVTSPPDPDVPYPDLAPVVFFCLKQTTSPRSWCIKMVCNPWFECVSMMVILLNCVTLGMYQPCEDMDCLSDRCKILQVFDDFIFIFFAMEMVLKMVALGIFGKKCYLGDTWNRLDFFIVMAGMVEYSLDLQNINLSAIRTVRVLRPLKAINRVPSMRILVNLLLDTLPMLGNVLLLCFFVFFIFGIIGVQLWAGLLRNRCDIVLPPYYQPEEDDEMPFICSLSGDNGIMGCHEIPPLKERGHECCLDKDDYYYYNSVRQEFNVSGMCVNWNQYYNVCRTGNANPHKGAINFDNIGYAWIVIFQVITLEGWVEIMYYVMDAHSFYNFIYFILLIIVGSFFMINLCLVVIATQFSETKQREHQLMQEQRARYLSSSTVASYMEPGDCYEEIFQYVCHIMRKAKRRTLGLYNSIQSRRQGHVEPSEAKRGASRKKQRHYSKDCTGESGNVNSGNRSVTESISMCYISKGLCRVSPEQWRQFLLMGHNPLDCPPQGLVQPIAVTATSDLTNCPRCHRGEHDTSRRLSVLDSADSDQEDGGDSEAEGEGCRGDHSASALEKEEEEVEEGGRMKLCSDMWREVRVKLRGIVDSKYFNRGIMIAILVNTISMGIEHHEQPEELTNILEISNVVFTSMFALEMILKLAAFGLFDYLRNPYNIFDSIIVIISIWEIIGQSDGGLSVLRTFRLLRVLKLVRFMPALRRQLVVLMKTMDNVATFCMLLMLFIFIFSILGMHIFGCKFSLRTDTGDTVPDRKNFDSLLWAIVTVFQILTQEDWNVVLYNGMASTSPWASLYFVALMTFGNYVLFNLLVAILVEGFQAEVSHQRCYTCGEKEDRCLKLCAISVTPNGHLDPSLPSSNAPVAAGGVSNSSRNSLQPDQIRVAVGSRKSSVMSLGRMTYDQRSLSSSRSSHYGAWGRSGAWGSRRSSWNSLARGHSLKHKPPSAEHESLLSGDRHRVGDREPDGLASIPSGHRGTCRPGTTSGGSEHQDCNGRMPSIAKEIFPKMNNRKERGEDDEEIDYSLCFRIRKMMEVYKPDWCELREDWSIYLFSPQNRFRLLCQTIIAHKLFDYVVLAFIFLNCITIALERPQIEHRSTERIFLTVSNYIFTAIFVAEMTLKVVSLGLYFGDQAYLRSSWNVLDGFLVFVSLIDIVVSVASAGGAKILGVLRVLRLLRTLRVISRAPGLKLVVETLISSLKPIGNIVLICCAFFIIFGILGVQLFKGKFYHCLGVDIRNITNRSDCVAANYKWVHHKYNFDNLGQALMSLFVLASKDGWVNIMYNGLDAVAVDQQPVTNNNPWMLLYFISFLLIVSFFVLNMFVGVVVENFHKCRQHQEAEEARRREEKRLRRLEKKRRKAQRLPYYATYCPIRLLIHSVCTSHYLDIFITFIICLNVVTMSLEHYNQPVSLETALKYCNYLFTTVFVLEAVLKLVAFGLRRFFKDRWNQLDLAIVLLSVMGITLEEIEINAALPINPTIIRIMRVLRIARVLKLLKMATGMRALLDTVVQALPQVGNLGLLFMLLFFIYAALGVELFGKLVCNDENPCEGMSRHATFENFGMAFLTLFQVSTGDNWNGIMKDTLRDCSHDDRSCLSNLQFISPLYFVSFVLTAQFVLINVVVAVLMKHLDDSNKEAQEDAEMDAEIELEFAHGLCSRKSGSSKSRQGKGAGSGSGGGRTEPEGRLCTRCYSPAQVGIPLSLPTRLQQAAVGRSQGA", "length": 1762, "header": "tr|A0A8V0YII9-1|A0A8V0YII9_CHICK Computationally mapped isoform of Voltage-dependent T-type calcium channel subunit alpha OS=Gallus gallus OX=9031 GN=CACNA1I PE=3 SV=1 CANONICAL=A0A8V0YNE5-1" }, "locus": { "chromosome": "1", "start_pos": 50598740, "end_pos": 50460127, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030378.1", "url": "https://www.ensembl.org/id/ENSGALT00010030378.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017621.1", "url": "https://www.ensembl.org/id/ENSGALP00010017621.1" } ] } }, { "isoform_ac": "A0A8V0YIL4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNE5/entry#A0A8V0YIL4-1", "sequence": { "sequence": "MAECTPQPPSTWPASPQPHNTSAACPLEPMNMGVSEQQMPLEQPPSSPELGEDEEVTSPPDPDVPYPDLAPVVFFCLKQTTSPRSWCIKMCVSMMVILLNCVTLGMYQPCEDMDCLSDRCKILQVFDDFIFIFFAMEMVLKMVALGIFGKKCYLGDTWNRLDFFIVMAGMVEYSLDLQNINLSAIRTVRVLRPLKAINRVPSMRILVNLLLDTLPMLGNVLLLCFFVFFIFGIIGVQLWAGLLRNRCFMEENFTIQGDIVLPPYYQPEEDDEMPFICSLSGDNGIMGCHEIPPLKERGHECCLDKDDYYYYNSVRQEFNVSGMCVNWNQYYNVCRTGNANPHKGAINFDNIGYAWIVIFQVITLEGWVEIMYYVMDAHSFYNFIYFILLIIVGSFFMINLCLVVIATQFSETKQREHQLMQEQRARYLSSSTVASYMEPGDCYEEIFQYVCHIMRKAKRRTLGLYNSIQSRRQGHVEPSEAKRGASRKKQRHYRICQQHNPLDCPPQGLVQPIAVTATSDLTNCPRCHRGEHDTSRRLSVLDSADSDQEDGGDSEAEGEGCRGDHSASALEKEEEEVEEGGRMKLCSDMWREVRVKLRGIVDSKYFNRGIMIAILVNTISMGIEHHEQPEELTNILEISNVVFTSMFALEMILKLAAFGLFDYLRNPYNIFDSIIVIISIWEIIGQSDGGLSVLRTFRLLRVLKLVRFMPALRRQLVVLMKTMDNVATFCMLLMLFIFIFSILGMHIFGCKFSLRTDTGDTVPDRKNFDSLLWAIVTVFQILTQEDWNVVLYNGMASTSPWASLYFVALMTFGNYVLFNLLVAILVEGFQAEGDANRSYSEEDQSSSNMEELDQFQEIQEGSDPKLCAISVTPNGHLDPSLPSSNAPVAAGGVSNSSRNSLQPDQIRVAVGSRKSSVMSLGRMTYDQRSLSSSRSSHYGAWGRSGAWGSRRSSWNSLARGHSLKHKPPSAEHESLLSGDRHRVGDREPDGAERVFHHRRTLSLDNKGSCDLLELASIPSGHRGTCRPGTTSGGSEHQDCNGRMPSIAKEIFPKMNNRKERGEDDEEIDYSLCFRIRKMMEVYKPDWCELREDWSIYLFSPQNRFRLLCQTIIAHKLFDYVVLAFIFLNCITIALERPQIEHRSTERIFLTVSNYIFTAIFVAEMTLKVVSLGLYFGDQAYLRSSWNVLDGFLVFVSLIDIVVSVASAGGAKILGVLRVLRLLRTLRVISRAPGLKLVVETLISSLKPIGNIVLICCAFFIIFGILGVQLFKGKFYHCLGVDIRNITNRSDCVAANYKWVHHKYNFDNLGQALMSLFVLASKDGWVNIMYNGLDAVAVDQQPVTNNNPWMLLYFISFLLIVSFFVLNMFVGVVVENFHKCRQHQEAEEARRREEKRLRRLEKKRRKAQRLPYYATYCPIRLLIHSVCTSHYLDIFITFIICLNVVTMSLEHYNQPVSLETALKYCNYLFTTVFVLEAVLKLVAFGLRRFFKDRWNQLDLAIVLLSVMGITLEEIEINAALPINPTIIRIMRVLRIARVLKLLKMATGMRALLDTVVQALPQVGNLGLLFMLLFFIYAALGVELFGKLVCNDENPCEGMSRHATFENFGMAFLTLFQVSTGDNWNGIMKDTLRDCSHDDRSCLSNLQFISPLYFVSFVLTAQFVLINVVVAVLMKHLDDSNKEAQEDAEMDAEIELEFAHGLCSRKSGSSKSRQGKGAGSGSGGGRTEPEGRLCTRCYSPAQENLWLDSVSLIIKDSFDGELMIIDNLSGSVFHHYSSPAMCEKCNHDKQEVQLAEMEALSLNSDKSSSILLGDESDNRSTSQLSPKETKDGQDSPDSTEAGDVGECLLPISSTDGSTNPDNYLCEIEKTPFNSVQSWLKHEGTKVPPSPFSPGTSCPLLPVPAEFFHPAISATQTGPEKVSCAHNLPKISLQGSWASLRSPSVNCSLLHQAPESDTSLDSRSSSSAGSLQTTLEDSLNLSDSPQCALDLPVALCPMPAASDPRPLAAPLSPTSRRRSLRGRGLFTLRSIRRHQRSHSSGGSTSPGCTHHDSMDPSDEEGAGSSLRGGGNNSEPSETLSSLSLTSLFSPPPPGLTLGKKCSSTSSLHASPSPRRPAAHHTKPFYTVDPKGFLSMPSWVTDFCKDTPPPVQGAEPDGSSRLGTGECGSPLPSELELGDGVSKRNR", "length": 2182, "header": "tr|A0A8V0YIL4-1|A0A8V0YNE5_CHICK Computationally mapped isoform of Calcium voltage-gated channel subunit alpha1 I OS=Gallus gallus OX=9031 GN=CACNA1I PE=4 SV=1 CANONICAL=A0A8V0YNE5-1" }, "locus": { "chromosome": "1", "start_pos": 50598740, "end_pos": 50450893, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030427.1", "url": "https://www.ensembl.org/id/ENSGALT00010030427.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017647.1", "url": "https://www.ensembl.org/id/ENSGALP00010017647.1" } ] } }, { "isoform_ac": "A0A8V0YIL9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNE5/entry#A0A8V0YIL9-1", "sequence": { "sequence": "MTSRSTISKQQMPLEQPPSSPELGEDEEVTSPPDPDVPYPDLAPVVFFCLKQTTSPRSWCIKMCVSMMVILLNCVTLGMYQPCEDMDCLSDRCKILQVFDDFIFIFFAMEMVLKMVALGIFGKKCYLGDTWNRLDFFIVMAGMVEYSLDLQNINLSAIRTVRVLRPLKAINRVPSMRILVNLLLDTLPMLGNVLLLCFFVFFIFGIIGVQLWAGLLRNRCFMEENFTIQGDIVLPPYYQPEEDDEMPFICSLSGDNGIMGCHEIPPLKERGHECCLDKDDYYYYNSVRQEFNVSGMCVNWNQYYNVCRTGNANPHKGAINFDNIGYAWIVIFQVITLEGWVEIMYYVMDAHSFYNFIYFILLIIVGSFFMINLCLVVIATQFSETKQREHQLMQEQRARYLSSSTVASYMEPGDCYEEIFQYVCHIMRKAKRRTLGLYNSIQSRRQGHVEPSEAKRGASRKKQRHYRICQQHNPLDCPPQGLVQPIAVTATSDLTNCPRCHRGEHDTSRRLSVLDSADSDQEDGGDSEAEGEGCRGDHSASALEKEEEEVEEGGRMKLCSDMWREVRVKLRGIVDSKYFNRGIMIAILVNTISMGIEHHEQPEELTNILEISNVVFTSMFALEMILKLAAFGLFDYLRNPYNIFDSIIVIISIWEIIGQSDGGLSVLRTFRLLRVLKLVRFMPALRRQLVVLMKTMDNVATFCMLLMLFIFIFSILGMHIFGCKFSLRTDTGDTVPDRKNFDSLLWAIVTVFQILTQEDWNVVLYNGMASTSPWASLYFVALMTFGNYVLFNLLVAILVEGFQAEGDANRSYSEEDQSSSNMEELDQFQEIQEGSDPKLCAISVTPNGHLDPSLPSSNAPVAAGGVSNSSRNSLQPDQIRVAVGSRKSSVMSLGRMTYDQRSLSSSRSSHYGAWGRSGAWGSRRSSWNSLARGHSLKHKPPSAEHESLLSGDRHRVGDREPDGAERVFHHRRTLSLDNKGSCDLLELASIPSGHRGTCRPGTTSGGSEHQDCNGRMPSIAKEIFPKMNNRKERGEDDEEIDYSLCFRIRKMMEVYKPDWCELREDWSIYLFSPQNRFRLLCQTIIAHKLFDYVVLAFIFLNCITIALERPQIEHRSTERIFLTVSNYIFTAIFVAEMTLKVVSLGLYFGDQAYLRSSWNVLDGFLVFVSLIDIVVSVASAGGAKILGVLRVLRLLRTLRVISRAPGLKLVVETLISSLKPIGNIVLICCAFFIIFGILGVQLFKGKFYHCLGVDIRNITNRSDCVAANYKWVHHKYNFDNLGQALMSLFVLASKDGWVNIMYNGLDAVAVDQQPVTNNNPWMLLYFISFLLIVSFFVLNMFVGVVVENFHKCRQHQEAEEARRREEKRLRRLEKKRRKAQRLPYYATYCPIRLLIHSVCTSHYLDIFITFIICLNVVTMSLEHYNQPVSLETALKYCNYLFTTVFVLEAVLKLVAFGLRRFFKDRWNQLDLAIVLLSVMGITLEEIEINAALPINPTIIRIMRVLRIARVLKLLKMATGMRALLDTVVQALPQVGNLGLLFMLLFFIYAALGVELFGKLVCNDENPCEGMSRHATFENFGMAFLTLFQVSTGDNWNGIMKDTLRDCSHDDRSCLSNLQFISPLYFVSFVLTAQFVLINVVVAVLMKHLDDSNKEAQEDAEMDAEIELEFAHGLCSRKSGSSKSRQGKGAGSGSGGGRTEPEGRLCTRCYSPAQENLWLDSVSLIIKDSFDGELMIIDNLSGSVFHHYSSPAMCEKCNHDKQEVQLAEMEALSLNSDKSSSILLGDESDNRSTSQLSPKETKVSLSPDSTEAGDVGECLLPISSTDGSTNPDNYLCEIEKTPFNSVQSWLKHEGTKVPPSPFSPGTSCPLLPVPAEFFHPAISATQTGPEKVSCAHNLPKISLQGSWASLRSPSVNCSLLHQAPESDTSLDSRSSSSAGSLQTTLEDSLNLSDSPQCALDLPVALCPMPAASDPRPLAAPLSPTSRRRSLRGRGLFTLRSIRRHQRSHSSGGSTSPGCTHHDSMDPSDEEGAGSSLRGGGNNSEPSETLSSLSLTSLFSPPPPGLTLGKKCSSTSSLHASPSPRRPAAHHTKPFYTVDPKGFLSMPSWVTDFCKDTPPPVQGAEPDGSSRLGTGECGSPLPSELELGDGVSKRNR", "length": 2154, "header": "tr|A0A8V0YIL9-1|A0A8V0YNE5_CHICK Computationally mapped isoform of Calcium voltage-gated channel subunit alpha1 I OS=Gallus gallus OX=9031 GN=CACNA1I PE=4 SV=1 CANONICAL=A0A8V0YNE5-1" }, "locus": { "chromosome": "1", "start_pos": 50599276, "end_pos": 50450893, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030435.1", "url": "https://www.ensembl.org/id/ENSGALT00010030435.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017652.1", "url": "https://www.ensembl.org/id/ENSGALP00010017652.1" } ] } }, { "isoform_ac": "A0A8V0YNE5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNE5/entry#A0A8V0YNE5-1", "sequence": { "sequence": 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"length": 2207, "header": "tr|A0A8V0YNE5-1|A0A8V0YNE5_CHICK Isoform 1 of Calcium voltage-gated channel subunit alpha1 I OS=Gallus gallus OX=9031 GN=CACNA1I PE=4 SV=1 CANONICAL=A0A8V0YNE5-1" }, "locus": { "chromosome": "1", "start_pos": 50598740, "end_pos": 50450893, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030418.1", "url": "https://www.ensembl.org/id/ENSGALT00010030418.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017640.1", "url": "https://www.ensembl.org/id/ENSGALP00010017640.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-445355", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-445355", "resource": "Reactome", "description": "Smooth Muscle Contraction" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "voltage-gated calcium channel activity", "id": "GO:0005245", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005245", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNE5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNE5" } ], "pmid": "" }, { "name": "high voltage-gated calcium channel activity", "id": "GO:0008331", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008331", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNE5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNE5" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNE5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNE5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "voltage-gated calcium channel complex", "id": "GO:0005891", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005891", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNE5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNE5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "calcium ion import across plasma membrane", "id": "GO:0098703", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098703", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNE5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNE5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1309, "end_pos": 1311, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1312, "end_pos": 1314, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1790, "end_pos": 1792, "annotation": "n_glycosylation_sequon" }, { "start_pos": 181, "end_pos": 183, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1841, "end_pos": 1843, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1968, "end_pos": 1970, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2002, "end_pos": 2004, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2093, "end_pos": 2095, "annotation": "n_glycosylation_sequon" }, { "start_pos": 20, "end_pos": 22, "annotation": "n_glycosylation_sequon" }, { "start_pos": 252, "end_pos": 254, "annotation": "n_glycosylation_sequon" }, { "start_pos": 319, "end_pos": 321, "annotation": "n_glycosylation_sequon" }, { "start_pos": 508, "end_pos": 510, "annotation": "n_glycosylation_sequon" }, { "start_pos": 861, "end_pos": 863, "annotation": "n_glycosylation_sequon" }, { "start_pos": 920, "end_pos": 922, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "29671", "name": "", "equation": "Ca(2+)(in) = Ca(2+)(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YTN5-1", "A0A8V0YTP2-1" ], "evidence": [ { "id": "29671", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/29671" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A8V0YTN5", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTN5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTN5" } ] } ] }, { "uniprot_ac": "A0A8V0YTP2", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTP2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTP2" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YNE5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNE5" }, { "id": "PF00520", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00520" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ion transport", "eco_id": "ECO_0000259", "start_pos": 91, "end_pos": 416, "start_aa": "Cys", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [ { "evidence": [ { "id": "A0A8V0YFD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFD7#function" }, { "id": "A0A8V0YFD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFD7" }, { "id": "PIRSR602077-1", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR602077-1" } ], "binding_site_uniprot": 1215, "amino_acid": "Gly", "chebi_lig_id": "CHEBI_29108", "ligand": "Ca(2+)", "ligand_label": "", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 1215, "end_pos": 1215, "start_aa": "Gly", "end_aa": "Gly", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0YFY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFY4#function" }, { "id": "A0A8V0YFY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFY4" }, { "id": "PIRSR602077-1", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR602077-1" } ], "binding_site_uniprot": 1232, "amino_acid": "Ala", "chebi_lig_id": "CHEBI_29108", "ligand": "Ca(2+)", "ligand_label": "", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 1232, "end_pos": 1232, "start_aa": "Ala", "end_aa": "Ala", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0YGA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGA2#function" }, { "id": "A0A8V0YGA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGA2" }, { "id": "PIRSR602077-1", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR602077-1" } ], "binding_site_uniprot": 1295, "amino_acid": "Phe", "chebi_lig_id": "CHEBI_29108", "ligand": "Ca(2+)", "ligand_label": "", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 1295, "end_pos": 1295, "start_aa": "Phe", "end_aa": "Phe", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0YI98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI98#function" }, { "id": "A0A8V0YI98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI98" }, { "id": "PIRSR602077-1", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR602077-1" } ], "binding_site_uniprot": 1320, "amino_acid": "Asn", "chebi_lig_id": "CHEBI_29108", "ligand": "Ca(2+)", "ligand_label": "", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 1320, "end_pos": 1320, "start_aa": "Asn", "end_aa": 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"https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR602077-1" } ], "binding_site_uniprot": 1328, "amino_acid": "Tyr", "chebi_lig_id": "CHEBI_29108", "ligand": "Ca(2+)", "ligand_label": "", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 1328, "end_pos": 1328, "start_aa": "Tyr", "end_aa": "Tyr", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0YFY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFY4#function" }, { "id": "A0A8V0YFY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFY4" }, { "id": "PIRSR602077-1", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR602077-1" } ], "binding_site_uniprot": 322, "amino_acid": "Gly", "chebi_lig_id": "CHEBI_29108", "ligand": "Ca(2+)", "ligand_label": "", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 322, "end_pos": 322, "start_aa": "Gly", "end_aa": "Gly", "glycosite_overlap": 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} ], "sequence": { "sequence": "MEEARMRKLEAGRAKFAHFRERKAKSNVTQSQKKTTKRKGSSVHTHDVPQEEHAAMGQGCDVGKGIESKAEDTNFLETTTETEKVAVHSAAEYSELDDKMRQTRIAELEKRLLEKQQAVGRLTVQMNELQEQLSQHRDSMQLQETTIQEQNEVIRKLTSCLQQTRKDWDDLQEEASHVADQIHGLQLQLHEVNVMLKSKGSGKKEVLEAQQQMSLFQSSLQEQNARLEMLHQRAYDLEVQLESSQKNTKDKECLLAPTEEGMKDTIQQLYESVGEKGDCIKSLQDLLASERFNLSILQRSLSLRDSEIKELKNEITLTKMKEQQHIEELKVNHEKDVCRQIEHLKVELEKCHRKETAEANQIYEEEMILKYKSEPGQLKKELTALNSEERIQNLNRIIINLNNSLHESEISKENLRKELVNQQENFQREKTEVEMQYKVLINDLKSQLSKAKEQVKEAQRYEQEKQCLNEEIQKLHYFIRELNKKRLFEAEKSKDAKQKHDEETVSNKNLREIRTLPDILELQTMKLEKMLNEPHRFKEELDPDKLDFQCQLRIDSVRDESEEIVCSKIREHNESSGDHLYEEPLPELGFFTTDEEILSKYLVFTERPEQSYVSGCSEGYTIEEDKHSRSGLDSNVFSDPSTDFKPPQLNFDLDEKTCHWSLTKETFEETKMEAEALISFLSDGSPLQNKISDYGDVKDDERACVLERCVKLTEQLHKKESALKKSHQETQEAVEKWKKVMAELCEINVELNKEREARLCCEEQLLQKTEREKELENKINLLVKQKDEDGSQSSSVTEPIAQASKSSTWQQMVKDLQEERQKSSAWQEMVKELQEEKEMLMVQLRTQEQLVKEVQEQKIASDSVTSEVQTLFGRQLAALQSQRDRMQNQLDAQKAKNQRITELLGQKTILEETMLKEQALLKAEINNKEQDLALLVKEKTVLGERLSVMEEDLGKAERALAANASIIADLEKNIHEVNAEVQNVKEVQECERLSYEDRLNLNNREINKLHAEIKAKSTEFGEKESQLIEEIAHLKKVHLELENYLRESFQSVQDAKKAQCEMMNYYKEEIVKMESQHLAELTKLSLTHKKEIEELNAEIKDKVEKQKKLEEERVEQLALVKKVHEREHDREISELIAKHKEEMEELRAELHKEKLHLLDELQQQMAATHKAEIEYAQLQSQTLHSLELEALRLSLNNLHTSQLELTQSNLRKEKETALVELREMLNDKRAQEIAILQSRHQLEWEKIKERCLKEKEDLTSKYQQELVDQRKKIELEMEEKHIQILETLKRDWELESEMRLKYTCEELSKKHKAEIAELQKTLEMELEKVKAELGLLSLEKEQSEMKCVDLEKQQQLAITTLTKQLQSEHNQLLEDVKIESQEKEQNLQKELEKLQVMHEEFKTRSQEEVKQLWSQLGSTRANRQELSELKEQLMARASQVEEIEHLKQKFEEQQQQTKSEHEAELEQLRIYFERKLRVTEENYREELTLLHQKLQELKEYSVSGVDVSHNQAGNISSSVIVFGEAVEKERKDFFLDQLNQQLEQHKEEIACLQGQLKEDHRHELDSLKSSLALQYKGDLLKMKMELSDKYIAEIEEMKRKHCLELEQLRARLSEEHIKEITKLRLQSAQDAARQVEMEVAKRVSVLEEEHKVKLSLLHSEEQHIAELSEEIKCLKEEMTKQKDFFVQNEKHLKEQMEQVKFKIAEDHENELKEAREEVLKIETLYKEKEKKWKCESEDQRVQAEEKLSLLHTELQNRLEYEKQNLQKEFEVREAQMNQLQDHQAAKIVELEKLVKEQQNNLKQLEDSLAVAQATRKSQEQYDSDLQAAKELMAKEMEKAELCLQEECALKLMKAQNKFMEEHKALTQKFTAEQEILLQELKKRHVDELELQSQQLQEKHKQEILSLTAEFQRKHQAEIKTLKSTLESKQQIQLEAFVAELQTKHQAQVDALEAKHLSNLDSLESSYLSEIQNIRGEHRLVLEKLQLHHTEQLHEKDKMNQACLAQEIEILKLKHSEELQLAQNNLKIELATVHMEKLKIMAVEAEEAHKDDLKAALQNQRSLLEEEKRLALDMLREEVVHMEEKHRKALQELQDLHEAEIKKHKEEYSRELEKELEKLKAQHKHEQEMYASASASEIETVRTALLSQFEAVKMKQQLQFQEEIELLKCQSEVLLEQQIAQLKDEFEAEKTALIHDQEQVLIQESEKAQAACQKEKETLSAQLQEKAARIIQLEKRVESLNCEIQETNCELETLIERRDRENQEGGNLVAMLRSDIEQSKDERKKMQDSYQCVLKWLVELVKATIAVEDLICSKIGLCLDNSMASADSMESHSIVEEIGFAQYFKAKEKSHLEKVDELLDETLTEHSQLSPVTEEQYELSQYLYESVFAKPEMAYENEEMILKICRRLRTAVERLLELVTESTKQLEKTHEIHAQFEEEFTRRNQETAQVVCQHRELMECLTEESEAKNQLALELHKAEGIIEGYVAEKAALEEALNLKEESERRLVVELENMRERFQELTQEQAILGLLKEVELLAKEKLELECQAEKDHSNLRSQMKVLEMELEEQLHSNQDLTKQLMETAELKQQIEVLEKQLKNQRQFMDEQAIERENERDDFQQEIKKLEEQLKLSAKLQTSGEPREYGNYDLILQVESLQAEVEEKVDDYNKLLLEKEQKHQEIAARDKEIEKLVAQVQELEHSSTEVSKTVNYLQQQLQKMKKVETELKQDKEALQQQQYNNLIQISALQSKLDEVRHGVPVEGTSDQELKEQLQAEQESLERKEGEIASLLDHLEQHKDILTSKNEEILQLKLQLEVQKNLSTSTINQLQIENAQLKDLAKLHVKQNRDSDVGDSSALSFPQALLEEKNQEIDHLNEQLRRLKYDQVNTLENKVVEDQKSEIEELRSVIEYLRGDQERLCKDKDEEVEQLHEVIEKLQKELAQIGPVCHEVSDNQGDIFQFGLEKSVENLQKELKKGLIDCQGDTDLDGRNALLLCKVRELEEDLEFASAAKKDLQQQLEEKESQFKMEVEILEKKCQNLQESSRQHFAELNTLRLQYHALQEEYSLLQTHISQRELEARIASSCVQELKDSMKEREVSILGKDSQIQAMAHQREADEGELRYLTEQASDLETELKKRDASQAQDVHSPELEVSRLDLHVQAMNQKEVSKQREIDELQGSTTKLKDQIKIYTKELEALHLERDELISQLELYKPKEQCDKENANCLELFCWGQRQGEVLKEGMEELESLETHVDQSFASPADNLEKVALFDFTAHDISKQSQVKQSEENISIQKLDMINSSEEQQTLKKHHHQTLDSPKIIVNAGCTEGTLKNFQDFIVDVTSWDSPEIMRKQDISMELPPALNLTPFSEAESTGLEMAHSRSSLQGDNSVLLGFSHLYENGSEEAAGRADVKSPVSSESIYSGADRDQDLKKTTLMSGTDNLTPSDLQDDVRSGASAIDVMSNGCDSSTRSNLEAKLKEQLQTSDHSDANFMAYLQYCGMFPDIMESVREKEILSPQLKTVLKLVYEESHKILALSEHSFGFRELKNVHQTKALMEGWQKEGLALLNAIQSLKDYLSKVADRGDKEEQRQMVVEHLFSSDRNSLLSEIQELRAQLRMTHLQNQEKLQQLQETLTSVEDHGSKQEHQLRRKVELLEYKLQQEKCIVSDLHSTLSEEQKRASETRELLSQEKAAVSTLKSDLYERKQENERLKKSLEEHQREINKLCFELESKEKDLTATLQELEAERLTETELRVLLEEQQLQHKKAEDEKKKALEDLQAALDLQTAQNRKLSVSLEHEQIINDNLRKELRIEYSRCEALLSQEHDKVLELQKNLDAERNRSLELLNSLNHERILTEQLSVQAKEDASCQRRELLLEQAFIRELQAQLEEERSQKTELAVITEKTHQRAIRSKRQLEAEVQMCCEETQKEKEITNKLRVMLDSLQSQKQEQNLELQHQRDEQRIKEMQEIVAILGETERSPPSPSSQQGLLCTSDKDQNAKEPMTIEIGKFNLQQQQKQQLEKIRQQLLFVAAHLIELMCKTVDKTVNDWYVSNDEAVASLLQTLKELKSDLLSPASQIRSTDDSNPVQELERAAWQQERNILQNALKQAESKLAKATAETENKPAMEAFNPKLQRLYRKYLRAESFRKALVYQKKYLLLLLGGFQDCEQATLSLIARMGIYPSPADLQLSASRSRPFTKFRCAVRAVIAVSRLKFLVKKWNKLNRKNAQAETVSQNTGSNTASGARTETLKQQQLTAVHVSSPPTWDTGLCHRTSSARSVSCSSKSSLRSHSRLPPSTSEKSPVPTQDPERSLTEYIHRLEIIQQRLGGMQPGQVPGPPCQRNMKK", "length": 4344, "header": "tr|A0A8V0YQC6-1|A0A8V0YQC6_CHICK Isoform 1 of Pericentrin OS=Gallus gallus OX=9031 GN=PCNT PE=4 SV=1 CANONICAL=A0A8V0YQC6-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YIQ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQC6/entry#A0A8V0YIQ8-1", "sequence": { "sequence": "MQESQARKQCILIYIFAHFRERKAKSNVTQSQKKTTKRKGSSVHTHDVPQEEHAAMGQGCDVGKGIESKAEDTNFLETTTETEKVAVHSAAEYSELDDKMRQTRIAELEKRLLEKQQAVGRLTVQMNELQEQLSQHRDSMQLQETTIQEQNEVIRKLTSCLQQTRKDWDDLQEEASHVADQIHGLQLQLHEVNVMLKSKGSGKKEVLEAQQQMSLFQSSLQEQNARLEMLHQRAYDLEVQLESSQKIEELNAEIKDKVEKQKKLEEERVEQLALVKKVHEREHDREISELIAKHKEEMEELRAELHKEKLHLLDELQQQMAATHKAEIEYAQLQSQTLHSLELEALRLSLNNLHTSQLELTQSNLRKEKETALVELREMLNDKRAQEIAILQSRHQLEWEKIKERCLKEKEDLTSKYQQELVDQRKKIELEMEEKHIQILETLKRDWELESEMRLKYTCEELSKKHKAEIAELQKTLEMELEKVKAELGLLSLEKEQSEMKCVDLEKQQQLAITTLTKQLQSEHNQLLEDVKIESQEKEQNLQKELEKLQVMHEEFKTRSQEEVKQLWSQLGSTRANRQELSELKEQLMARASQVEEIEHLKQKFEEQQQQTKSEHEAELEQLRIYFERKLRVTEENYREELTLLHQKLQELKEYSVSGVDVSHNQAGNISSSVIVFGEAVEKERKDFFLDQLNQQLEQHKEEIACLQGQLKEDHRHELDSLKSSLALQYKGDLLKMKMELSDKYIAEIEEMKRKHCLELEQLRARLSEEHIKEITKLRLQSAQDAARQVEMEVAKRVSVLEEEHKVKLSLLHSEEQHIAELSEEIKCLKEEMTKQKDFFVQNEKHLKEQMEQVKFKIAEDHENELKEAREEVLKIETLYKEKEKKWKCESEDQRVQAEEKLSLLHTELQNRLEYEKQNLQKEFEVREAQMNQLQDHQAAKIVELEKLVKEQQNNLKQLEDSLAVAQATRKSQEQYDSDLQAAKELMAKEMEKAELCLQEECALKLMKAQNKFMEEHKALTQKFTAEQEILLQELKKRHVDELELQSQQLQEKHKQEILSLTAEFQRKHQAEIKTLKSTLESKQQIQLEAFVAELQTKHQAQVDALEAKHLSNLDSLESSYLSEIQNIRGEHRLVLEKLQLHHTEQLHEKDKMNQACLAQEIEILKLKHSEELQLAQNNLKIELATVHMEKLKIMAVEAEEAHKDDLKAALQNQRSLLEEEKRLALDMLREEVVHMEEKHRKALQELQDLHEAEIKKHKEEYSRELEKELEKLKAQHKHEQEMYASASASEIETVRTALLSQFEAVKMKQQLQFQEEIELLKCQSEVLLEQQIAQLKDEFEAEKTALIHDQEQVLIQESEKAQAACQKEKETLSAQLQEKAARIIQLEKRVESLNCEIQETNCELETLIERRDRENQEGGNLVAMLRSDIEQSKDERKKMQDSYQCVLKWLVELVKATIAVEDLICSKIGLCLDNSMASADSMESHSIVEEIGFAQYFKAKEKSHLEKVDELLDETLTEHSQLSPVTEEQYELSQYLYESVFAKPEMAYENEEMILKICRRLRTAVERLLELVTESTKQLEKTHEIHAQFEEEFTRRNQETAQVVCQHRELMECLTEESEAKNQLALELHKAEGIIEGYVAEKAALEEALNLKEESERRLVVELENMRERFQELTQEQAILGLLKEVELLAKEKLELECQAEKDHSNLRSQMKVLEMELEEQLHSNQDLTKQLMETAELKQQIEVLEKQLKNQRQFMDEQAIERENERDDFQQEIKKLEEQLKLSAKLQTSGEPREYGVESLQAEVEEKVDDYNKLLLEKEQKHQEIAARDKEIEKLVAQVQELEHSSTEVSKTVNYLQQQLQKMKKVETELKQDKEALQQQQYNNLIQISALQSKLDEVRHGVPVEGTSDQELKEQLQAEQESLERKEGEIASLLDHLEQHKDILTSKNEEILQLKLQLEVQKNLSTSTINQLQIENAQLKDLAKLHVKQNRDSDVGDSSALSFPQALLEEKNQEIDHLNEQLRRLKYDQVNTLENKVVEDQKSEIEELRSVIEYLRGDQERLCKDKDEEVEQLHEVIEKLQKELAQIGPVCHEVSDNQGDIFQFGLEKSVENLQKELKKGLIDCQGDTDLDGRNALLLCKVRELEEDLEFASAAKKDLQQQLEEKESQFKMEVEILEKKCQNLQESSRQHFAELNTLRLQYHALQEEYSLLQTHISQRELEARIASSCVQELKDSMKEREVSILGKDSQIQAMAHQREADEGELRYLTEQASDLETELKKRDASQAQDVHSPELEVSRLDLHVQAMNQKEVSKQREIDELQGSTTKLKDQIKIYTKELEALHLERDELISQLELYKPKEQCDKENANCLELFCWGQRQGEVLKEGMEELESLETHVDQSFASPADNLEKVALFDFTAHDISKQSQVKQSEENISIQKLDMINSSEEQQTLKKHHHQTLDSPKIIVNAGCTEGTLKNFQDFIVDVTSWDSPEIMRKQDISMELPPALNLTPFSEAESTGLEMAHSRSSLQGDNSVLLGFSHLYENGSEEAAGRADVKSPVSSESIYSGADRDQDLKKTTLMSGTDNLTPSDLQDDVRSGASAIDVMSNGCDSSTRSNLEAKLKEQLQTSDHSDANFMAYLQYCGMFPDIMESVREKEILSPQLKTVLKLVYEESHKILALSEHSFGFRELKNVHQTKALMEGWQKEGLALLNAIQSLKDYLSKVADRGDKEEQRQMVVEHLFSSDRNSLLSEIQELRAQLRMTHLQNQEKLQQLQETLTSVEDHGSKQEHQLRRKVELLEYKLQQEKCIVSDLHSTLSEEQKRASETRELLSQEKAAVSTLKSDLYERKQENERLKKSLEEHQREINKLCFELESKEKDLTATLQELEAERLTETELRVLLEEQQLQHKKAEDEKKKALEDLQAALDLQTAQNRKLSVSLEHEQIINDNLRKELRIEYSRCEALLSQEHDKVLELQKNLDAERNRSLELLNSLNHERILTEQLSVQAKEDASCQRRELLLEQAFIRELQAQLEEERSQKTELAVITEKTHQRAIRSKRQLEAEVQMCCEETQKEKEITNKLRVMLDSLQSQKQEQNLELQHQRDEQRIKEMQEIVAILGETERSPPSPSSQQGLLCTSDKDQNAKEPMTIEIGKFNLQQQQKQQLEKIRQQLLFVAAHLIELMCKTVDKTVNDWYVSNDEAVASLLQTLKELKSDLLSPASQIRSTDDSNPVQELERAAWQQERNILQNALKQAESKLAKATAETENKPAMEAFNPKLQRLYRKYLRAESFRKALVYQKKYLLLLLGGFQDCEQATLSLIARMGIYPSPADLQLSASRSRPFTKFRCAVRAVIAVSRLKFLVKKWNKLNRKNAQAETVSQNTGSNTASGARTETLKQQQLTAVHVSSPPTWDTGLCHRTSSARSVSCSSKSSLRSHSRLPPSTSEKSPVPTQDPERSLTEYIHRLEIIQQRLGGMQPGKRRPGPPGSYSSGVFGMSSP", "length": 3499, "header": "tr|A0A8V0YIQ8-1|A0A8V0YQC6_CHICK Computationally mapped isoform of Pericentrin OS=Gallus gallus OX=9031 GN=PCNT PE=4 SV=2 CANONICAL=A0A8V0YQC6-1" }, "locus": { "chromosome": "7", "start_pos": 7175773, "end_pos": 7084783, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010035857.1", "url": "https://www.ensembl.org/id/ENSGALT00010035857.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020795.1", "url": "https://www.ensembl.org/id/ENSGALP00010020795.1" } ] } }, { "isoform_ac": "A0A8V0YIY5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQC6/entry#A0A8V0YIY5-1", "sequence": { "sequence": "MEEARMRKLEAGRAKFAHFRERKAKSNVTQSQKKTTKRKGSSVHTHDVPQEEHAAMGQGCDVGKGIESKAEDTNFLETTTETEKVAVHSAAEYSELDDKMRQTRIAELEKRLLEKQQAVGRLTVQMNELQEQLSQHRDSMQLQETTIQEQNEVIRKLTSCLQQTRKDWDDLQEEASHVADQIHGLQLQLHEVNVMLKSKGSGKKEVLEAQQQMSLFQSSLQEQNARLEMLHQRAYDLEVQLESSQKNTKDKECLLAPTEEGMKDTIQQLYESVGEKGDCIKSLQDLLASERFNLSILQRSLSLRDSEIKELKNEITLTKMKEQQHIEELKVNHEKDVCRQIEHLKVELEKCHRKETAEANQIYEEEMILKYKSEPGQLKKELTALNSEERIQNLNRIIINLNNSLHESEISKENLRKELVNQQENFQREKTEVEMQYKVLINDLKSQLSKAKEQVKEAQRYEQEKQCLNEEIQKLHYFIRELNKKRLFEAEKSKDAKQKHDEETVSNKNLREIRTLPDILELQTMKLEKMLNEPHRFKEELDPDKLDFQCQLRIDSVRDESEEIVCSKIREHNESSGDHLYEEPLPELGFFTTDEEILSKYLVFTERPEQSYVSGCSEGYTIEEDKHSRSGLDSNVFSDPSTDFKPPQLNFDLDEKTCHWSLTKETFEETKMEAEALISFLSDGSPLQNKISDYGDVKDDERACVLERCVKLTEQLHKKESALKKSHQETQEAVEKWKKVMAELCEINVELNKEREARLCCEEQLLQKTEREKELENKINLLVKQKDEDGSQSSSVTEPIAQASKSSTWQQMVKDLQEERQKSSAWQEMVKELQEEKEMLMVQLRTQEQLVKEVQEQKIASDSVTSEVQTLFGRQLAALQSQRDRMQNQLDAQKAKNQRITELLGQKTILEETMLKEQALLKAEINNKEQDLALLVKEKTVLGERLSVMEEDLGKAERALAANASIIADLEKNIHEVNAEVQNVKEVQECERLSYEDRLNLNNREINKLHAEIKAKSTEFGEKESQLIEEIAHLKKVHLELENYLRESFQSVQDAKKAQCEMMNYYKEEIVKMESQHLAELTKLSLTHKKEIEELNAEIKDKVEKQKKLEEERVEQLALVKKVHEREHDREISELIAKHKEEMEELRAELHKEKLHLLDELQQQMAATHKAEIEYAQLQSQTLHSLELEALRLSLNNLHTSQLELTQSNLRKEKETALVELREMLNDKRAQEIAILQSRHQLEWEKIKERCLKEKEDLTSKYQQELVDQRKKIELEMEEKHIQILETLKRDWELESEMRLKYTCEELSKKHKAEIAELQKTLEMELEKVKAELGLLSLEKEQSEMKCVDLEKQQQLAITTLTKQLQSEHNQLLEDVKIESQEKEQNLQKELEKLQVMHEEFKTRSQEEVKQLWSQLGSTRANRQELSELKEQLMARASQVEEIEHLKQKFEEQQQQTKSEHEAELEQLRIYFERKLRVTEENYREELTLLHQKLQELKEYSVSGVDVSHNQAGNISSSVIVFGEAVEKERKDFFLDQLNQQLEQHKEEIACLQGQLKEDHRHELDSLKSSLALQYKGDLLKMKMELSDKYIAEIEEMKRKHCLELEQLRARLSEEHIKEITKLRLQSAQDAARQVEMEVAKRVSVLEEEHKVKLSLLHSEEQHIAELSEEIKCLKEEMTKQKDFFVQNEKHLKEQMEQVKFKIAEDHENELKEAREEVLKIETLYKEKEKKWKCESEDQRVQAEEKLSLLHTELQNRLEYEKQNLQKEFEVREAQMNQLQDHQAAKIVELEKLVKEQQNNLKQLEDSLAVAQATRKSQEQYDSDLQAAKELMAKEMEKAELCLQEECALKLMKAQNKFMEEHKALTQKFTAEQEILLQELKKRHVDELELQSQQLQEKHKQEILSLTAEFQRKHQAEIKTLKSTLESKQQIQLEAFVAELQTKHQAQVDALEAKHLSNLDSLESSYLSEIQNIRGEHRLVLEKLQLHHTEQLHEKDKMNQACLAQEIEILKLKHSEELQLAQNNLKIELATVHMEKLKIMAVEAEEAHKDDLKAALQNQRSLLEEEKRLALDMLREEVVHMEEKHRKALQELQDLHEAEIKKHKEEYSRELEKELEKLKAQHKHEQEMYASASASEIETVRTALLSQFEAVKMKQQLQFQEEIELLKCQSEVLLEQQIAQLKDEFEAEKTALIHDQEQVLIQESEKAQAACQKEKETLSAQLQEKAARIIQLEKRVESLNCEIQETNCELETLIERRDRENQEGGNLVAMLRSDIEQSKDERKKMQDSYQCVLKWLVELVKATIAVEDLICSKIGLCLDNSMASADSMESHSIVEEIGFAQYFKAKEKSHLEKDELLDETLTEHSQLSPVTEEQYELSQYLYESVFAKPEMAYENEEMILKICRRLRTAVERLLELVTESTKQLEKTHEIHAQFEEEFTRRNQETAQVVCQHRELMECLTEESEAKNQLALELHKAEGIIEGYVAEKAALEEALNLKEESERRLVVELENMRERFQELTQEQAILGLLKEVELLAKEKLELECQAEKDHSNLRSQMKVLEMELEEQLHSNQDLTKQLMETAELKQQIEVLEKQLKNQRQFMDEQAIERENERDDFQQEIKKLEEQLKLSAKLQTSGEPREYGVESLQAEVEEKVDDYNKLLLEKEQKHQEIAARDKEIEKLVAQVQELEHSSTEVSKTVNYLQQQLQKMKKVETELKQDKEALQQQQYNNLIQISALQSKLDEVRHGVPVEGTSDQELKEQLQAEQESLERKEGEIASLLDHLEQHKDILTSKNEEILQLKLQLEVQKNLSTSTINQLQIENAQLKDLAKLHVKQNRDSDVGDSSALSFPQALLEEKNQEIDHLNEQLRRLKYDQVNTLENKVVEDQKSEIEELRSVIEYLRGDQERLCKDKDEEVEQLHEVIEKLQKELAQIGPVCHEVSDNQGDIFQFGLEKSVENLQKELKKGLIDCQGDTDLDGRNALLLCKVRELEEDLEFASAAKKDLQQQLEEKESQFKMEVEILEKKCQNLQESSRQHFAELNTLRLQYHALQEEYSLLQTHISQRELEARIASSCVQELKDSMKEREVSILGKDSQIQAMAHQREADEGELRYLTEQASDLETELKKRDASQAQDVHSPELEVSRLDLHVQAMNQKEVSKQREIDELQGSTTKLKDQIKIYTKELEALHLERDELISQLELYKPKEQCDKENANCLELFCWGQRQGEVLKEGMEELESLETHVDQSFASPADNLEKVALFDFTAHDISKQSQVKQSEENISIQKLDMINSSEEQQTLKKHHHQTLDSPKIIVNAGCTEGTLKNFQDFIVDVTSWDSPEIMRKQDISMELPPALNLTPFSEAESTGLEMAHSRSSLQGDNSVLLGFSHLYENGSEEAAGRADVKSPVSSESIYSGADRDQDLKKTTLMSGTDNLTPSDLQDDVRSGASAIDVMSNGCDSSTRSNLEAKLKEQLQTSDHSDANFMAYLQYCGMFPDIMESVREKEILSPQLKTVLKLVYEESHKILALSEHSFGFRELKNVHQTKALMEGWQKEGLALLNAIQSLKDYLSKVADRGDKEEQRQMVVEHLFSSDRNSLLSEIQELRAQLRMTHLQNQEKLQQLQETLTSVEDHGSKQEHQLRRKVELLEYKLQQEKCIVSDLHSTLSEEQKRASETRELLSQEKAAVSTLKSDLYERKQENERLKKSLEEHQREINKLCFELESKEKDLTATLQELEAERLTETELRVLLEEQQLQHKKAEDEKKKALEDLQAALDLQTAQNRKLSVSLEHEQIINDNLRKELRIEYSRCEALLSQEHDKVLELQKNLDAERNRSLELLNSLNHERILTEQLSVQAKEDASCQRRELLLEQAFIRELQAQLEEERSQKTELAVITEKTHQRAIRSKRQLEAEVQMCCEETQKEKEITNKLRVMLDSLQSQKQEQNLELQHQRDEQRIKEMQEIVAILGETERSPPSPSSQQGLLCTSDKDQNAKEPMTIEIGKFNLQQQQKQQLEKIRQQLLFVAAHLIELMCKTVDKTVNDWYVSNDEAVASLLQTLKELKSDLLSPASQIRSTDDSNPVQELERAAWQQERNILQNALKQAESKLAKATAETENKPAMEAFNPKLQRLYRKYLRAESFRKALVYQKKYLLLLLGGFQDCEQATLSLIARMGIYPSPADLQLSASRSRPFTKFRCAVRAVIAVSRLKFLVKKWNKLNRKNAQAETVSQNTGSNTASGARTETLKQQQLTAVHVSSPPTWDTGLCHRTSSARSVSCSSKSSLRSHSRLPPSTSEKSPVPTQDPERSLTEYIHRLEIIQQRLGGMQPGQVPGPPCQRNMKK", "length": 4336, "header": "tr|A0A8V0YIY5-1|A0A8V0YQC6_CHICK Computationally mapped isoform of Pericentrin OS=Gallus gallus OX=9031 GN=PCNT PE=4 SV=1 CANONICAL=A0A8V0YQC6-1" }, "locus": { "chromosome": "7", "start_pos": 7180631, "end_pos": 7083087, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010035953.1", "url": "https://www.ensembl.org/id/ENSGALT00010035953.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020871.1", "url": "https://www.ensembl.org/id/ENSGALP00010020871.1" } ] } }, { "isoform_ac": "A0A8V0YQ20-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQC6/entry#A0A8V0YQ20-1", "sequence": { "sequence": "MKDTIQQLYESVGEKGDCIKSLQDLLASERFNLSILQRSLSLRDSEIKELKNEITLTKMKEQQHIEELKVNHEKDVCRQIEHLKVELEKCHRKETAEANQIYEEEMILKYKSEPGQLKKELTALNSEERIQNLNRIIINLNNSLHESEISKENLRKELVNQQENFQREKTEVEMQYKVLINDLKSQLSKAKEQVKEAQRYEQEKQCLNEEIQKLHYFIRELNKKRLFEAEKSKDAKQKHDEETVSNKNLREIRTLPDILELQTMKLEKMLNEPHRFKEELDPDKLDFQCQLRIDSVRDESEEIVCSKIREHNESSGDHLYEEPLPELGFFTTDEEILSKYLVFTERPEQSYVSGCSEGYTIEEDKHSRSGLDSNVFSDPSTDFKPPQLNFDLDEKTCHWSLTKETFEETKMEAEALISFLSDGSPLQNKISDYGDVKDDERACVLERCVKLTEQLHKKESALKKSHQETQEAVEKWKKVMAELCEINVELNKEREARLCCEEQLLQKTEREKELENKINLLVKQKDEDGSQSSSVTEPIAQASKSSTWQQMVKDLQEERQKSSAWQEMVKELQEEKEMLMVQLRTQEQLVKEVQEQKIASDSVTSEVQTLFGRQLAALQSQRDRMQNQLDAQKAKNQRITELLGQKTILEETMLKEQALLKAEINNKEQDLALLVKEKTVLGERLSVMEEDLGKAERALAANASIIADLEKNIHEVNAEVQNVKEVQECERLSYEDRLNLNNREINKLHAEIKAKSTEFGEKESQLIEEIAHLKKVHLELENYLRESFQSVQDAKKAQCEMMNYYKEEIVKMESQHLAELTKLSLTHKKEIEELNAEIKDKVEKQKKLEEERVEQLALVKKVHEREHDREISELIAKHKEEMEELRAELHKEKLHLLDELQQQMAATHKAEIEYAQLQSQTLHSLELEALRLSLNNLHTSQLELTQSNLRKEKETALVELREMLNDKRAQEIAILQSRHQLEWEKIKERCLKEKEDLTSKYQQELVDQRKKIELEMEEKHIQILETLKRDWELESEMRLKYTCEELSKKHKAEIAELQKTLEMELEKVKAELGLLSLEKEQSEMKCVDLEKQQQLAITTLTKQLQSEHNQLLEDVKIESQEKEQNLQKELEKLQVMHEEFKTRSQEEVKQLWSQLGSTRANRQELSGGESVWLRMEAHVPELKEQLMARASQVEEIEHLKQKFEEQQQQTKSEHEAELEQLRIYFERKLRVTEENYREELTLLHQKLQELKEYSVSGVDVSHNQAGNISSSVIVFGEAVEKERKDFFLDQLNQQLEQHKEEIACLQGQLKEDHRHELDSLKSSLALQYKGDLLKMKMELSDKYIAEIEEMKRKHCLELEQLRARLSEEHIKEITKLRLQSAQDAARQVEMEVAKRVSVLEEEHKVKLSLLHSEEQHIAELSEEIKCLKEEMTKQKDFFVQNEKHLKEQMEQVKFKIAEDHENELKEAREEVLKIETLYKEKEKKWKCESEDQRVQAEEKLSLLHTELQNRLEYEKQNLQKEFEVREAQMNQLQDHQAAKIVELEKLVKEQQNNLKQLEDSLAVAQATRKSQEQYDSDLQAAKELMAKEMEKAELCLQEECALKLMKAQNKFMEEHKALTQKFTAEQEILLQELKKRHVDELELQSQQLQEKHKQEILSLTAEFQRKHQAEIKTLKSTLESKQQIQLEAFVAELQTKHQAQVDALEAKHLSNLDSLESSYLSEIQNIRGEHRLVLEKLQLHHTEQLHEKDKMNQACLAQEIEILKLKHSEELQLAQNNLKIELATVHMEKLKIMAVEAEEAHKDDLKAALQNQRSLLEEEKRLALDMLREEVVHMEEKHRKALQELQDLHEAEIKKHKEEYSRELEKELEKLKAQHKHEQEMYASASASEIETVRTALLSQFEAVKMKQQLQFQEEIELLKCQSEVLLEQQIAQLKDEFEAEKTALIHDQEQVLIQESEKAQAACQKEKETLSAQLQEKAARIIQLEKRVESLNCEIQETNCELETLIERRDRENQEGGNLVAMLRSDIEQSKDERKKMQDSYQCVLKWLVELVKATIAVEDLICSKIGLCLDNSMASADSMESHSIVEEIGFAQYFKAKEKSHLEKDELLDETLTEHSQLSPVTEEQYELSQYLYESVFAKPEMAYENEEMILKICRRLRTAVERLLELVTESTKQLEKTHEIHAQFEEEFTRRNQETAQVVCQHRELMECLTEESEAKNQLALELHKAEGLLKEVELLAKEKLELECQAEKDHSNLRSQMKVLEMELEEQLHSNQDLTKQLMETAELKQQIEVLEKQLKNQRQFMDEQAIERENERDDFQQEIKKLEEQLKLSAKLQTSGEPREYGNYDLILQVESLQAEVEEKVDDYNKLLLEKEQKHQEIAARDKEIEKLVAQVQELEHSSTEVSKTVNYLQQQLQKMKKVETELKQDKEALQQQQYNNLIQISALQSKLDEVRHGVPVEGTSDQELKEQLQAEQESLERKEGEIASLLDHLEQHKDILTSKNEEILQLKLQLEVQKNLSTSTINQLQIENAQLKDLAKLHVKQNRDSDVGDSSALSFPQALLEEKNQEIDHLNEQLRRLKYDQVNTLENKVVEDQKSEIEELRSVIEYLRGDQERLCKDKDEEVEQLHEVIEKLQKELAQIGPVCHEVSDNQGDIFQFGLEKSVENLQKELKKGLIDCQGDTDLDGRNALLLCKVRELEEDLEFASAAKKDLQQQLEEKESQFKMEVEILEKKCQNLQESSRQHFAELNTLRLQYHALQEEYSLLQTHISQRELEARIASSCVQELKDSMKEREVSILGKDSQIQAMAHQREADEGELRYLTEQASDLETELKKRDASQAQDVHSPELEVSRLDLHVQAMNQKEVSKQREIDELQGSTTKLKDQIKIYTKELEALHLERDELISQLELYKPKEQCDKENANCLELFCWGQRQGEVLKEGMEELESLETHVDQSFASPADNLEKVALFDFTAHDISKQSQVKQSEENISIQKLDMINSSEEQQTLKKHHHQTLDSPKIIVNAGCTEGTLKNFQDFIVDVTSWDSPEIMRKQDISMELPPALNLTPFSEAESTGLEMAHSRSSLQGDNSVLLGFSHLYENGSEEAAGRADVKSPVSSESIYSGADRDQDLKKTTLMSGTDNLTPSDLQDDVRSGASAIDVMSNGCDSSTRSNLEAKLKEQLQTSDHSDANFMAYLQYCGMFPDIMESVREKEILSPQLKTVLKLVYEESHKILALSEHSFGFRELKNVHQTKALMEGWQKEGLALLNAIQSLKDYLSKVADRGDKEEQRQMVVEHLFSSDRNSLLSEIQELRAQLRMTHLQNQEKLQQLQETLTSVEDHGSKQEHQLRRKVELLEYKLQQEKCIVSDLHSTLSEEQKRASETRELLSQEKAAVSTLKSDLYERKQENERLKKSLEEHQREINKLCFELESKEKDLTATLQELEAERLTETELRVLLEEQQLQHKKAEDEKKKALEDLQAALDLQTAQNRKLSVSLEHEQIINDNLRKELRIEYSRCEALLSQEHDKVLELQKNLDAERNRSLELLNSLNHERILTEQLSVQAKEDASCQRRELLLEQAFIRELQAQLEEERSQKTELAVITEKTHQRAIRSKRQLEAEVQMCCEETQKEKEITNKLRVMLDSLQSQKQEQNLELQHQRDEQRIKEMQEIVAILGETERSPPSPSSQQGLLCTSDKDQNAKEPMTIEIGKFNLQQQQKQQLEKIRQQLLFVAAHLIELMCKTVDKTVNDWYVSNDEAVASLLQTLKELKSDLLSPASQVRKMACICSLSGNHSVFF", "length": 3797, "header": "tr|A0A8V0YQ20-1|A0A8V0YQ20_CHICK Computationally mapped isoform of Pericentrin OS=Gallus gallus OX=9031 GN=PCNT PE=4 SV=1 CANONICAL=A0A8V0YQC6-1" }, "locus": { "chromosome": "7", "start_pos": 7164999, "end_pos": 7096593, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010035805.1", "url": "https://www.ensembl.org/id/ENSGALT00010035805.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020762.1", "url": "https://www.ensembl.org/id/ENSGALP00010020762.1" } ] } }, { "isoform_ac": "A0A8V0YQ63-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQC6/entry#A0A8V0YQ63-1", "sequence": { "sequence": "MEEARMRKLEAGRAKFAHFRERKAKSNVTQSQKKTTKRKGSSVHTHDVPQEEHAAMGQGCDVGKGIESKAEDTNFLETTTETEKVAVHSAAEYSELDDKMRQTRIAELEKRLLEKQQAVGRLTVQMNELQEQLSQHRDSMQLQETTIQEQNEVIRKLTSCLQQTRKDWDDLQEEASHVADQIHGLQLQLHEVNVMLKSKGSGKKEVLEAQQQMSLFQSSLQEQNARLEMLHQRAYDLEVQLESSQKNTKDKECLLAPTEEGMKDTIQQLYESVGEKGDCIKSLQDLLASERFNLSILQRSLSLRDSEIKELKNEITLTKMKEQQHIEELKVNHEKDVCRQIEHLKVELEKCHRKETAEANQIYEEEMILKYKSEPGQLKKELTALNSEERIQNLNRIIINLNNSLHESEISKENLRKELVNQQENFQREKTEVEMQYKVLINDLKSQLSKAKEQVKEAQRYEQEKQCLNEEIQKLHYFIRELNKKRLFEAEKSKDAKQKHDEETVSNKNLREIRTLPDILELQTMKLEKMLNEPHRFKEELDPDKLDFQCQLRIDSVRDESEEIVCSKIREHNESSGDHLYEEPLPELGFFTTDEEILSKYLVFTERPEQSYVSGCSEGYTIEEDKHSRSGLDSNVFSDPSTDFKPPQLNFDLDEKTCHWSLTKETFEETKMEAEALISFLSDGSPLQNKISDYGDVKDDERACVLERCVKLTEQLHKKESALKKSHQETQEAVEKWKKVMAELCEINVELNKEREARLCCEEQLLQKTEREKELENKINLLVKQKDEDGSQSSSVTEPIAQASKSSTWQQMVKDLQEERQKSSAWQEMVKELQEEKEMLMVQLRTQEQLVKEVQEQKIASDSVTSEVQTLFGRQLAALQSQRDRMQNQLDAQKAKNQRITELLGQKTILEETMLKEQALLKAEINNKEQDLALLVKEKTVLGERLSVMEEDLGKAERALAANASIIADLEKNIHEVNAEVQNVKEVQECERLSYEDRLNLNNREINKLHAEIKAKSTEFGEKESQLIEEIAHLKKVHLELENYLRESFQSVQDAKKAQCEMMNYYKEEIVKMESQHLAELTKLSLTHKKEIEELNAEIKDKVEKQKKLEEERVEQLALVKKVHEREHDREISELIAKHKEEMEELRAELHKEKLHLLDELQQQMAATHKAEIEYAQLQSQTLHSLELEALRLSLNNLHTSQLELTQSNLRKEKETALVELREMLNDKRAQEIAILQSRHQLEWEKIKERCLKEKEDLTSKYQQELVDQRKKIELEMEEKHIQILETLKRDWELESEMRLKYTCEELSKKHKAEIAELQKTLEMELEKVKAELGLLSLEKEQSEMKCVDLEKQQQLAITTLTKQLQSEHNQLLEDVKIESQEKEQNLQKELEKLQVMHEEFKTRSQEEVKQLWSQLGSTRANRQELSGGESVWLRMEAHVPELKEQLMARASQVEEIEHLKQKFEEQQQQTKSEHEAELEQLRIYFERKLRVTEENYREELTLLHQKLQELKEYSVSGVDVSHNQAGNISSSVIVFGEAVEKERKDFFLDQLNQQLEQHKEEIACLQGQLKEDHRHELDSLKSSLALQYKGDLLKMKMELSDKYIAEIEEMKRKHCLELEQLRARLSEEHIKEITKLRLQSAQDAARQVEMEVAKRVSVLEEEHKVKLSLLHSEEQHIAELSEEIKCLKEEMTKQKDFFVQNEKHLKEQMEQVKFKIAEDHENELKEAREEVLKIETLYKEKEKKWKCESEDQRVQAEEKLSLLHTELQNRLEYEKQNLQKEFEVREAQMNQLQDHQAAKIVELEKLVKEQQNNLKQLEDSLAVAQATRKSQEQYDSDLQAAKELMAKEMEKAELCLQEECALKLMKAQNKFMEEHKALTQKFTAEQEILLQELKKRHVDELELQSQQLQEKHKQEILSLTAEFQRKHQAEIKTLKSTLESKQQIQLEAFVAELQTKHQAQVDALEAKHLSNLDSLESSYLSEIQNIRGEHRLVLEKLQLHHTEQLHEKDKMNQACLAQEIEILKLKHSEELQLAQNNLKIELATVHMEKLKIMAVEAEEAHKDDLKAALQNQRSLLEEEKRLALDMLREEVVHMEEKHRKALQELQDLHEAEIKKHKEEYSRELEKELEKLKAQHKHEQEMYASASASEIETVRTALLSQFEAVKMKQQLQFQEEIELLKCQSEVLLEQQIAQLKDEFEAEKTALIHDQEQVLIQESEKAQAACQKEKETLSAQLQEKAARIIQLEKRVESLNCEIQETNCELETLIERRDRENQEGGNLVAMLRSDIEQSKDERKKMQDSYQCVLKWLVELVKATIAVEDLICSKIGLCLDNSMASADSMESHSIVEEIGFAQYFKAKEKSHLEKDELLDETLTEHSQLSPVTEEQYELSQYLYESVFAKPEMAYENEEMILKICRRLRTAVERLLELVTESTKQLEKTHEIHAQFEEEFTRRNQETAQVVCQHRELMECLTEESEAKNQLALELHKAEGIIEGYVAEKAALEEALNLKEESERRLVVELENMRERFQELTQEQAILGLLKEVELLAKEKLELECQAEKDHSNLRSQMKVLEMELEEQLHSNQDLTKQLMETAELKQQIEVLEKQLKNQRQFMDEQAIERENERDDFQQEIKKLEEQLKLSAKLQTSGEPREYGVESLQAEVEEKVDDYNKLLLEKEQKHQEIAARDKEIEKLVAQVQELEHSSTEVSKTVNYLQQQLQKMKKVETELKQDKEALQQQQYNNLIQISALQSKLDEVRHGVPVEGTSDQELKEQLQAEQESLERKEGEIASLLDHLEQHKDILTSKNEEILQLKLQLEVQKNLSTSTINQLQIENAQLKDLAKLHVKQNRDSDVGDSSALSFPQALLEEKNQEIDHLNEQLRRLKYDQVNTLENKVVEDQKSEIEELRSVIEYLRGDQERLCKDKDEEVEQLHEVIEKLQKELAQIGPVCHEVSDNQGDIFQFGLEKSVENLQKELKKGLIDCQGDTDLDGRNALLLCKVRELEEDLEFASAAKKDLQQQLEEKESQFKMEVEILEKKCQNLQESSRQHFAELNTLRLQYHALQEEYSLLQTHISQRELEARIASSCVQELKDSMKEREVSILGKDSQIQAMAHQREADEGELRYLTEQASDLETELKKRDASQAQDVHSPELEVSRLDLHVQAMNQKEVSKQREIDELQGSTTKLKDQIKIYTKELEALHLERDELISQLELYKPKEQCDKENANCLELFCWGQRQGEVLKEGMEELESLETHVDQSFASPADNLEKVALFDFTAHDISKQSQVKQSEENISIQKLDMINSSEEQQTLKKHHHQTLDSPKIIVNAGCTEGTLKNFQDFIVDVTSWDSPEIMRKQDISMELPPALNLTPFSEAESTGLEMAHSRSSLQGDNSVLLGFSHLYENGSEEAAGRADVKSPVSSESIYSGADRDQDLKKTTLMSGTDNLTPSDLQDDVRSGASAIDVMSNGCDSSTRSNLEAKLKEQLQTSDHSDANFMAYLQYCGMFPDIMESVREKEILSPQLKTVLKLVYEESHKILALSEHSFGFRELKNVHQTKALMEGWQKEGLALLNAIQSLKDYLSKVADRGDKEEQRQMVVEHLFSSDRNSLLSEIQELRAQLRMTHLQNQEKLQQLQETLTSVEDHGSKQEHQLRRKVELLEYKLQQEKCIVSDLHSTLSEEQKRASETRELLSQEKAAVSTLKSDLYERKQENERLKKSLEEHQREINKLCFELESKEKDLTATLQELEAERLTETELRVLLEEQQLQHKKAEDEKKKALEDLQAALDLQTAQNRKLSVSLEHEQIINDNLRKELRIEYSRCEALLSQEHDKVLELQKNLDAERNRSLELLNSLNHERILTEQLSVQAKEDASCQRRELLLEQAFIRELQAQLEEERSQKTELAVITEKTHQRAIRSKRQLEAEVQMCCEETQKEKEITNKLRVMLDSLQSQKQEQNLELQHQRDEQRIKEMQEIVAILGETERSPPSPSSQQGLLCTSDKDQNAKEPMTIEIGKFNLQQQQKQQLEKIRQQLLFVAAHLIELMCKTVDKTVNDWYVSNDEAVASLLQTLKELKSDLLSPASQIRSTDDSNPVQELERAAWQQERNILQNALKQAESKLAKATAETENKPAMEAFNPKLQRLYRKYLRAESFRKALVYQKKYLLLLLGGFQDCEQATLSLIARMGIYPSPADLQLSASRSRPFTKFRCAVRAVIAVSRLKFLVKKWNKLNRKNAQAETVSQNTGSNTASGARTETLKQQQLTAVHVSSPPTWDTGLCHRTSSARSVSCSSKSSLRSHSRSVCSLDGV", "length": 4305, "header": "tr|A0A8V0YQ63-1|A0A8V0YQ63_CHICK Computationally mapped isoform of Pericentrin OS=Gallus gallus OX=9031 GN=PCNT PE=4 SV=1 CANONICAL=A0A8V0YQC6-1" }, "locus": { "chromosome": "7", "start_pos": 7180631, "end_pos": 7087867, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010035865.1", "url": "https://www.ensembl.org/id/ENSGALT00010035865.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020803.1", "url": "https://www.ensembl.org/id/ENSGALP00010020803.1" } ] } }, { "isoform_ac": "A0A8V0YQC6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQC6/entry#A0A8V0YQC6-1", "sequence": { "sequence": "MEEARMRKLEAGRAKFAHFRERKAKSNVTQSQKKTTKRKGSSVHTHDVPQEEHAAMGQGCDVGKGIESKAEDTNFLETTTETEKVAVHSAAEYSELDDKMRQTRIAELEKRLLEKQQAVGRLTVQMNELQEQLSQHRDSMQLQETTIQEQNEVIRKLTSCLQQTRKDWDDLQEEASHVADQIHGLQLQLHEVNVMLKSKGSGKKEVLEAQQQMSLFQSSLQEQNARLEMLHQRAYDLEVQLESSQKNTKDKECLLAPTEEGMKDTIQQLYESVGEKGDCIKSLQDLLASERFNLSILQRSLSLRDSEIKELKNEITLTKMKEQQHIEELKVNHEKDVCRQIEHLKVELEKCHRKETAEANQIYEEEMILKYKSEPGQLKKELTALNSEERIQNLNRIIINLNNSLHESEISKENLRKELVNQQENFQREKTEVEMQYKVLINDLKSQLSKAKEQVKEAQRYEQEKQCLNEEIQKLHYFIRELNKKRLFEAEKSKDAKQKHDEETVSNKNLREIRTLPDILELQTMKLEKMLNEPHRFKEELDPDKLDFQCQLRIDSVRDESEEIVCSKIREHNESSGDHLYEEPLPELGFFTTDEEILSKYLVFTERPEQSYVSGCSEGYTIEEDKHSRSGLDSNVFSDPSTDFKPPQLNFDLDEKTCHWSLTKETFEETKMEAEALISFLSDGSPLQNKISDYGDVKDDERACVLERCVKLTEQLHKKESALKKSHQETQEAVEKWKKVMAELCEINVELNKEREARLCCEEQLLQKTEREKELENKINLLVKQKDEDGSQSSSVTEPIAQASKSSTWQQMVKDLQEERQKSSAWQEMVKELQEEKEMLMVQLRTQEQLVKEVQEQKIASDSVTSEVQTLFGRQLAALQSQRDRMQNQLDAQKAKNQRITELLGQKTILEETMLKEQALLKAEINNKEQDLALLVKEKTVLGERLSVMEEDLGKAERALAANASIIADLEKNIHEVNAEVQNVKEVQECERLSYEDRLNLNNREINKLHAEIKAKSTEFGEKESQLIEEIAHLKKVHLELENYLRESFQSVQDAKKAQCEMMNYYKEEIVKMESQHLAELTKLSLTHKKEIEELNAEIKDKVEKQKKLEEERVEQLALVKKVHEREHDREISELIAKHKEEMEELRAELHKEKLHLLDELQQQMAATHKAEIEYAQLQSQTLHSLELEALRLSLNNLHTSQLELTQSNLRKEKETALVELREMLNDKRAQEIAILQSRHQLEWEKIKERCLKEKEDLTSKYQQELVDQRKKIELEMEEKHIQILETLKRDWELESEMRLKYTCEELSKKHKAEIAELQKTLEMELEKVKAELGLLSLEKEQSEMKCVDLEKQQQLAITTLTKQLQSEHNQLLEDVKIESQEKEQNLQKELEKLQVMHEEFKTRSQEEVKQLWSQLGSTRANRQELSELKEQLMARASQVEEIEHLKQKFEEQQQQTKSEHEAELEQLRIYFERKLRVTEENYREELTLLHQKLQELKEYSVSGVDVSHNQAGNISSSVIVFGEAVEKERKDFFLDQLNQQLEQHKEEIACLQGQLKEDHRHELDSLKSSLALQYKGDLLKMKMELSDKYIAEIEEMKRKHCLELEQLRARLSEEHIKEITKLRLQSAQDAARQVEMEVAKRVSVLEEEHKVKLSLLHSEEQHIAELSEEIKCLKEEMTKQKDFFVQNEKHLKEQMEQVKFKIAEDHENELKEAREEVLKIETLYKEKEKKWKCESEDQRVQAEEKLSLLHTELQNRLEYEKQNLQKEFEVREAQMNQLQDHQAAKIVELEKLVKEQQNNLKQLEDSLAVAQATRKSQEQYDSDLQAAKELMAKEMEKAELCLQEECALKLMKAQNKFMEEHKALTQKFTAEQEILLQELKKRHVDELELQSQQLQEKHKQEILSLTAEFQRKHQAEIKTLKSTLESKQQIQLEAFVAELQTKHQAQVDALEAKHLSNLDSLESSYLSEIQNIRGEHRLVLEKLQLHHTEQLHEKDKMNQACLAQEIEILKLKHSEELQLAQNNLKIELATVHMEKLKIMAVEAEEAHKDDLKAALQNQRSLLEEEKRLALDMLREEVVHMEEKHRKALQELQDLHEAEIKKHKEEYSRELEKELEKLKAQHKHEQEMYASASASEIETVRTALLSQFEAVKMKQQLQFQEEIELLKCQSEVLLEQQIAQLKDEFEAEKTALIHDQEQVLIQESEKAQAACQKEKETLSAQLQEKAARIIQLEKRVESLNCEIQETNCELETLIERRDRENQEGGNLVAMLRSDIEQSKDERKKMQDSYQCVLKWLVELVKATIAVEDLICSKIGLCLDNSMASADSMESHSIVEEIGFAQYFKAKEKSHLEKVDELLDETLTEHSQLSPVTEEQYELSQYLYESVFAKPEMAYENEEMILKICRRLRTAVERLLELVTESTKQLEKTHEIHAQFEEEFTRRNQETAQVVCQHRELMECLTEESEAKNQLALELHKAEGIIEGYVAEKAALEEALNLKEESERRLVVELENMRERFQELTQEQAILGLLKEVELLAKEKLELECQAEKDHSNLRSQMKVLEMELEEQLHSNQDLTKQLMETAELKQQIEVLEKQLKNQRQFMDEQAIERENERDDFQQEIKKLEEQLKLSAKLQTSGEPREYGNYDLILQVESLQAEVEEKVDDYNKLLLEKEQKHQEIAARDKEIEKLVAQVQELEHSSTEVSKTVNYLQQQLQKMKKVETELKQDKEALQQQQYNNLIQISALQSKLDEVRHGVPVEGTSDQELKEQLQAEQESLERKEGEIASLLDHLEQHKDILTSKNEEILQLKLQLEVQKNLSTSTINQLQIENAQLKDLAKLHVKQNRDSDVGDSSALSFPQALLEEKNQEIDHLNEQLRRLKYDQVNTLENKVVEDQKSEIEELRSVIEYLRGDQERLCKDKDEEVEQLHEVIEKLQKELAQIGPVCHEVSDNQGDIFQFGLEKSVENLQKELKKGLIDCQGDTDLDGRNALLLCKVRELEEDLEFASAAKKDLQQQLEEKESQFKMEVEILEKKCQNLQESSRQHFAELNTLRLQYHALQEEYSLLQTHISQRELEARIASSCVQELKDSMKEREVSILGKDSQIQAMAHQREADEGELRYLTEQASDLETELKKRDASQAQDVHSPELEVSRLDLHVQAMNQKEVSKQREIDELQGSTTKLKDQIKIYTKELEALHLERDELISQLELYKPKEQCDKENANCLELFCWGQRQGEVLKEGMEELESLETHVDQSFASPADNLEKVALFDFTAHDISKQSQVKQSEENISIQKLDMINSSEEQQTLKKHHHQTLDSPKIIVNAGCTEGTLKNFQDFIVDVTSWDSPEIMRKQDISMELPPALNLTPFSEAESTGLEMAHSRSSLQGDNSVLLGFSHLYENGSEEAAGRADVKSPVSSESIYSGADRDQDLKKTTLMSGTDNLTPSDLQDDVRSGASAIDVMSNGCDSSTRSNLEAKLKEQLQTSDHSDANFMAYLQYCGMFPDIMESVREKEILSPQLKTVLKLVYEESHKILALSEHSFGFRELKNVHQTKALMEGWQKEGLALLNAIQSLKDYLSKVADRGDKEEQRQMVVEHLFSSDRNSLLSEIQELRAQLRMTHLQNQEKLQQLQETLTSVEDHGSKQEHQLRRKVELLEYKLQQEKCIVSDLHSTLSEEQKRASETRELLSQEKAAVSTLKSDLYERKQENERLKKSLEEHQREINKLCFELESKEKDLTATLQELEAERLTETELRVLLEEQQLQHKKAEDEKKKALEDLQAALDLQTAQNRKLSVSLEHEQIINDNLRKELRIEYSRCEALLSQEHDKVLELQKNLDAERNRSLELLNSLNHERILTEQLSVQAKEDASCQRRELLLEQAFIRELQAQLEEERSQKTELAVITEKTHQRAIRSKRQLEAEVQMCCEETQKEKEITNKLRVMLDSLQSQKQEQNLELQHQRDEQRIKEMQEIVAILGETERSPPSPSSQQGLLCTSDKDQNAKEPMTIEIGKFNLQQQQKQQLEKIRQQLLFVAAHLIELMCKTVDKTVNDWYVSNDEAVASLLQTLKELKSDLLSPASQIRSTDDSNPVQELERAAWQQERNILQNALKQAESKLAKATAETENKPAMEAFNPKLQRLYRKYLRAESFRKALVYQKKYLLLLLGGFQDCEQATLSLIARMGIYPSPADLQLSASRSRPFTKFRCAVRAVIAVSRLKFLVKKWNKLNRKNAQAETVSQNTGSNTASGARTETLKQQQLTAVHVSSPPTWDTGLCHRTSSARSVSCSSKSSLRSHSRLPPSTSEKSPVPTQDPERSLTEYIHRLEIIQQRLGGMQPGQVPGPPCQRNMKK", "length": 4344, "header": "tr|A0A8V0YQC6-1|A0A8V0YQC6_CHICK Isoform 1 of Pericentrin OS=Gallus gallus OX=9031 GN=PCNT PE=4 SV=1 CANONICAL=A0A8V0YQC6-1" }, "locus": { "chromosome": "7", "start_pos": 7180631, "end_pos": 7083087, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010035941.1", "url": "https://www.ensembl.org/id/ENSGALT00010035941.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020860.1", "url": "https://www.ensembl.org/id/ENSGALP00010020860.1" } ] } }, { "isoform_ac": "A0A8V0YQD4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQC6/entry#A0A8V0YQD4-1", "sequence": { "sequence": "MEEARMRKLEAGRAKFAHFRERKAKSNVTQSQKKTTKRKGSSVHTHDVPQEEHAAMGQGCDVGKGIESKAEDTNFLETTTETEKVAVHSAAEYSELDDKMRQTRIAELEKRLLEKQQAVGRLTVQMNELQEQLSQHRDSMQLQETTIQEQNEVIRKLTSCLQQTRKDWDDLQEEASHVADQIHGLQLQLHEVNVMLKSKGSGKKEVLEAQQQMSLFQSSLQEQNARLEMLHQRAYDLEVQLESSQKIEELNAEIKDKVEKQKKLEEERVEQLALVKKVHEREHDREISELIAKHKEEMEELRAELHKEKLHLLDELQQQMAATHKAEIEYAQLQSQTLHSLELEALRLSLNNLHTSQLELTQSNLRKEKETALVELREMLNDKRAQEIAILQSRHQLEWEKIKERCLKEKEDLTSKYQQELVDQRKKIELEMEEKHIQILETLKRDWELESEMRLKYTCEELSKKHKAEIAELQKTLEMELEKVKAELGLLSLEKEQSEMKCVDLEKQQQLAITTLTKQLQSEHNQLLEDVKIESQEKEQNLQKELEKLQVMHEEFKTRSQEEVKQLWSQLGSTRANRQELSELKEQLMARASQVEEIEHLKQKFEEQQQQTKSEHEAELEQLRIYFERKLRVTEENYREELTLLHQKLQELKEYSVSGVDVSHNQAGNISSSVIVFGEAVEKERKDFFLDQLNQQLEQHKEEIACLQGQLKEDHRHELDSLKSSLALQYKGDLLKMKMELSDKYIAEIEEMKRKHCLELEQLRARLSEEHIKEITKLRLQSAQDAARQVEMEVAKRVSVLEEEHKVKLSLLHSEEQHIAELSEEIKCLKEEMTKQKDFFVQNEKHLKEQMEQVKFKIAEDHENELKEAREEVLKIETLYKEKEKKWKCESEDQRVQAEEKLSLLHTELQNRLEYEKQNLQKEFEVREAQMNQLQDHQAAKIVELEKLVKEQQNNLKQLEDSLAVAQATRKSQEQYDSDLQAAKELMAKEMEKAELCLQEECALKLMKAQNKFMEEHKALTQKFTAEQEILLQELKKRHVDELELQSQQLQEKHKQEILSLTAEFQRKHQAEIKTLKSTLESKQQIQLEAFVAELQTKHQAQVDALEAKHLSNLDSLESSYLSEIQNIRGEHRLVLEKLQLHHTEQLHEKDKMNQACLAQEIEILKLKHSEELQLAQNNLKIELATVHMEKLKIMAVEAEEAHKDDLKAALQNQRSLLEEEKRLALDMLREEVVHMEEKHRKALQELQDLHEAEIKKHKEEYSRELEKELEKLKAQHKHEQEMYASASASEIETVRTALLSQFEAVKMKQQLQFQEEIELLKCQSEVLLEQQIAQLKDEFEAEKTALIHDQEQVLIQESEKAQAACQKEKETLSAQLQEKAARIIQLEKRVESLNCEIQETNCELETLIERRDRENQEGGNLVAMLRSDIEQSKDERKKMQDSYQCVLKWLVELVKATIAVEDLICSKIGLCLDNSMASADSMESHSIVEEIGFAQYFKAKEKSHLEKDELLDETLTEHSQLSPVTEEQYELSQYLYESVFAKPEMAYENEEMILKICRRLRTAVERLLELVTESTKQLEKTHEIHAQFEEEFTRRNQETAQVVCQHRELMECLTEESEAKNQLALELHKAEGIIEGYVAEKAALEEALNLKEESERRLVVELENMRERFQELTQEQAILGLLKEVELLAKEKLELECQAEKDHSNLRSQMKVLEMELEEQLHSNQDLTKQLMETAELKQQIEVLEKQLKNQRQFMDEQAIERENERDDFQQEIKKLEEQLKLSAKLQTSGEPREYGNYDLILQVESLQAEVEEKVDDYNKLLLEKEQKHQEIAARDKEIEKLVAQVQELEHSSTEVSKTVNYLQQQLQKMKKVETELKQDKEALQQQQYNNLIQISALQSKLDEVRHGVPVEGTSDQELKEQLQAEQESLERKEGEIASLLDHLEQHKDILTSKNEEILQLKLQLEVQKNLSTSTINQLQIENAQLKDLAKLHVKQNRDSDVGDSSALSFPQALLEEKNQEIDHLNEQLRRLKYDQVNTLENKVVEDQKSEIEELRSVIEYLRGDQERLCKDKDEEVEQLHEVIEKLQKELAQIGPVCHEVSDNQGDIFQFGLEKSVENLQKELKKGLIDCQGDTDLDGRNALLLCKVRELEEDLEFASAAKKDLQQQLEEKESQFKMEVEILEKKCQNLQESSRQHFAELNTLRLQYHALQEEYSLLQTHISQRELEARIASSCVQELKDSMKEREVSILGKDSQIQAMAHQREADEGELRYLTEQASDLETELKKRDASQAQDVHSPELEVSRLDLHVQAMNQKEVSKQREIDELQGSTTKLKDQIKIYTKELEALHLERDELISQLELYKPKEQCDKENANCLELFCWGQRQGEVLKEGMEELESLETHVDQSFASPADNLEKVALFDFTAHDISKQSQVKQSEENISIQKLDMINSSEEQQTLKKHHHQTLDSPKIIVNAGCTEGTLKNFQDFIVDVTSWDSPEIMRKQDISMELPPALNLTPFSEAESTGLEMAHSRSSLQGDNSVLLGFSHLYENGSEEAAGRADVKSPVSSESIYSGADRDQDLKKTTLMSGTDNLTPSDLQDDVRSGASAIDVMSNGCDSSTRSNLEAKLKEQLQTSDHSDANFMAYLQYCGMFPDIMESVREKEILSPQLKTVLKLVYEESHKILALSEHSFGFRELKNVHQTKALMEGWQKEGLALLNAIQSLKDYLSKVADRGDKEEQRQMVVEHLFSSDRNSLLSEIQELRAQLRMTHLQNQEKLQQLQETLTSVEDHGSKQEHQLRRKVELLEYKLQQEKCIVSDLHSTLSEEQKRASETRELLSQEKAAVSTLKSDLYERKQENERLKKSLEEHQREINKLCFELESKEKDLTATLQELEAERLTETELRVLLEEQQLQHKKAEDEKKKALEDLQAALDLQTAQNRKLSVSLEHEQIINDNLRKELRIEYSRCEALLSQEHDKVLELQKNLDAERNRSLELLNSLNHERILTEQLSVQAKEDASCQRRELLLEQAFIRELQAQLEEERSQKTELAVITEKTHQRAIRSKRQLEAEVQMCCEETQKEKEITNKLRVMLDSLQSQKQEQNLELQHQRDEQRIKEMQEIVAILGETERSPPSPSSQQGLLCTSDKDQNAKEPMTIEIGKFNLQQQQKQQLEKIRQQLLFVAAHLIELMCKTVDKTVNDWYVSNDEAVASLLQTLKELKSDLLSPASQIRSTDDSNPVQELERAAWQQERNILQNALKQAESKLAKATAETENKPAMEAFNPKLQRLYRKYLRAESFRKALVYQKKYLLLLLGGFQDCEQATLSLIARMGIYPSPADLQLSASRSRPFTKFRCAVRAVIAVSRLKFLVKKWNKLNRKNAQAETVSQNTGSNTASGARTETLKQQQLTAVHVSSPPTWDTGLCHRTSSARSVSCSSKSSLRSHSRLPPSTSEKSPVPTQDPERSLTEYIHRLEIIQQRLGGMQPGQVPGPPCQRNMKK", "length": 3498, "header": "tr|A0A8V0YQD4-1|A0A8V0YQD4_CHICK Computationally mapped isoform of Pericentrin OS=Gallus gallus OX=9031 GN=PCNT PE=4 SV=1 CANONICAL=A0A8V0YQC6-1" }, "locus": { "chromosome": "7", "start_pos": 7180631, "end_pos": 7083087, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010035946.1", "url": "https://www.ensembl.org/id/ENSGALT00010035946.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020865.1", "url": "https://www.ensembl.org/id/ENSGALP00010020865.1" } ] } }, { "isoform_ac": "A0A8V0YWX7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQC6/entry#A0A8V0YWX7-1", "sequence": { "sequence": "MEEARMRKLEAGRAKFAHFRERKAKSNVTQSQKKTTKRKGSSVHTHDVPQEEHAAMGQGCDVGKGIESKAEDTNFLETTTETEKVAVHSAAEYSELDDKMRQTRIAELEKRLLEKQQAVGRLTVQMNELQEQLSQHRDSMQLQETTIQEQNEVIRKLTSCLQQTRKDWDDLQEEASHVADQIHGLQLQLHEVNVMLKSKGSGKKEVLEAQQQMSLFQSSLQEQNARLEMLHQRAYDLEVQLESSQKVHEREHDREISELIAKHKEEMEELRAELHKEKLHLLDELQQQMAATHKAEIEYAQLQSQTLHSLELEALRLSLNNLHTSQLELTQSNLRKEKETALVELREMLNDKRAQEIAILQSRHQLEWEKIKERCLKEKEDLTSKYQQELVDQRKKIELEMEEKHIQILETLKRDWELESEMRLKYTCEELSKKHKAEIAELQKTLEMELEKVKAELGLLSLEKEQSEMKCVDLEKQQQLAITTLTKQLQSEHNQLLEDVKIESQEKEQNLQKELEKLQVMHEEFKTRSQEEVKQLWSQLGSTRANRQELSELKEQLMARASQVEEIEHLKQKFEEQQQQTKSEHEAELEQLRIYFERKLRVTEENYREELTLLHQKLQELKEYSVSGVDVSHNQAGNISSSVIVFGEAVEKERKDFFLDQLNQQLEQHKEEIACLQGQLKEDHRHELDSLKSSLALQYKGDLLKMKMELSDKYIAEIEEMKRKHCLELEQLRARLSEEHIKEITKLRLQSAQDAARQVEMEVAKRVSVLEEEHKVKLSLLHSEEQHIAELSEEIKCLKEEMTKQKDFFVQNEKHLKEQMEQVKFKIAEDHENELKEAREEVLKIETLYKEKEKKWKCESEDQRVQAEEKLSLLHTELQNRLEYEKQNLQKEFEVREAQMNQLQDHQAAKIVELEKLVKEQQNNLKQLEDSLAVAQATRKSQEQYDSDLQAAKELMAKEMEKAELCLQEECALKLMKAQNKFMEEHKALTQKFTAEQEILLQELKKRHVDELELQSQQLQEKHKQEILSLTAEFQRKHQAEIKTLKSTLESKQQIQLEAFVAELQTKHQAQVDALEAKHLSNLDSLESSYLSEIQNIRGEHRLVLEKLQLHHTEQLHEKDKMNQACLAQEIEILKLKHSEELQLAQNNLKIELATVHMEKLKIMAVEAEEAHKDDLKAALQNQRSLLEEEKRLALDMLREEVVHMEEKHRKALQELQDLHEAEIKKHKEEYSRELEKELEKLKAQHKHEQEMYASASASEIETVRTALLSQFEAVKMKQQLQFQEEIELLKCQSEVLLEQQIAQLKDEFEAEKTALIHDQEQVLIQESEKAQAACQKEKETLSAQLQEKAARIIQLEKRVESLNCEIQETNCELETLIERRDRENQEGGNLVAMLRSDIEQSKDERKKMQDSYQCVLKWLVELVKATIAVEDLICSKIGLCLDNSMASADSMESHSIVEEIGFAQYFKAKEKSHLEKDELLDETLTEHSQLSPVTEEQYELSQYLYESVFAKPEMAYENEEMILKICRRLRTAVERLLELVTESTKQLEKTHEIHAQFEEEFTRRNQETAQVVCQHRELMECLTEESEAKNQLALELHKAEGIIEGYVAEKAALEEALNLKEESERRLVVELENMRERFQELTQEQAILGLLKEVELLAKEKLELECQAEKDHSNLRSQMKVLEMELEEQLHSNQDLTKQLMETAELKQQIEVLEKQLKNQRQFMDEQAIERENERDDFQQEIKKLEEQLKLSAKLQTSGEPREYGNYDLILQVESLQAEVEEKVDDYNKLLLEKEQKHQEIAARDKEIEKLVAQVQELEHSSTEVSKTVNYLQQQLQKMKKVETELKQDKEALQQQQYNNLIQISALQSKLDEVRHGVPVEGTSDQELKEQLQAEQESLERKEGEIASLLDHLEQHKDILTSKNEEILQLKLQLEVQKNLSTSTINQLQIENAQLKDLAKLHVKQNRDSDVGDSSALSFPQALLEEKNQEIDHLNEQLRRLKYDQVNTLENKVVEDQKSEIEELRSVIEYLRGDQERLCKDKDEEVEQLHEVIEKLQKELAQIGPVCHEVSDNQGDIFQFGLEKSVENLQKELKKGLIDCQGDTDLDGRNALLLCKVRELEEDLEFASAAKKDLQQQLEEKESQFKMEVEILEKKCQNLQESSRQHFAELNTLRLQYHALQEEYSLLQTHISQRELEARIASSCVQELKDSMKEREVSILGKDSQIQAMAHQREADEGELRYLTEQASDLETELKKRDASQAQDVHSPELEVSRLDLHVQAMNQKEVSKQREIDELQGSTTKLKDQIKIYTKELEALHLERDELISQLELYKPKEQCDKENANCLELFCWGQRQGEVLKEGMEELESLETHVDQSFASPADNLEKVALFDFTAHDISKQSQVKQSEENISIQKLDMINSSEEQQTLKKHHHQTLDSPKIIVNAGCTEGTLKNFQDFIVDVTSWDSPEIMRKQDISMELPPALNLTPFSEAESTGLEMAHSRSSLQGDNSVLLGFSHLYENGSEEAAGRADVKSPVSSESIYSGADRDQDLKKTTLMSGTDNLTPSDLQDDVRSGASAIDVMSNGCDSSTRSNLEAKLKEQLQTSDHSDANFMAYLQYCGMFPDIMESVREKEILSPQLKTVLKLVYEESHKILALSEHSFGFRELKNVHQTKALMEGWQKEGLALLNAIQSLKDYLSKVADRGDKEEQRQMVVEHLFSSDRNSLLSEIQELRAQLRMTHLQNQEKLQQLQETLTSVEDHGSKQEHQLRRKVELLEYKLQQEKCIVSDLHSTLSEEQKRASETRELLSQEKAAVSTLKSDLYERKQENERLKKSLEEHQREINKLCFELESKEKDLTATLQELEAERLTETELRVLLEEQQLQHKKAEDEKKKALEDLQAALDLQTAQNRKLSVSLEHEQIINDNLRKELRIEYSRCEALLSQEHDKVLELQKNLDAERNRSLELLNSLNHERILTEQLSVQAKEDASCQRRELLLEQAFIRELQAQLEEERSQKTELAVITEKTHQRAIRSKRQLEAEVQMCCEETQKEKEITNKLRVMLDSLQSQKQEQNLELQHQRDEQRIKEMQEIVAILGETERSPPSPSSQQGLLCTSDKDQNAKEPMTIEIGKFNLQQQQKQQLEKIRQQLLFVAAHLIELMCKTVDKTVNDWYVSNDEAVASLLQTLKELKSDLLSPASQIRSTDDSNPVQELERAAWQQERNILQNALKQAESKLAKATAETENKPAMEAFNPKLQRLYRKYLRAESFRKALVYQKKYLLLLLGGFQDCEQATLSLIARMGIYPSPADLQLSASRSRPFTKFRCAVRAVIAVSRLKFLVKKWNKLNRKNAQAETVSQNTGSNTASGARTETLKQQQLTAVHVSSPPTWDTGLCHRTSSARSVSCSSKSSLRSHSRLPPSTSEKSPVPTQDPERSLTEYIHRLEIIQQRLGGMQPVLCAWQVWMIRC", "length": 3465, "header": "tr|A0A8V0YWX7-1|A0A8V0YWX7_CHICK Computationally mapped isoform of Pericentrin OS=Gallus gallus OX=9031 GN=PCNT PE=4 SV=1 CANONICAL=A0A8V0YQC6-1" }, "locus": { "chromosome": "7", "start_pos": 7180631, "end_pos": 7083661, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010035869.1", "url": "https://www.ensembl.org/id/ENSGALT00010035869.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020807.1", "url": "https://www.ensembl.org/id/ENSGALP00010020807.1" } ] } }, { "isoform_ac": "A0A8V0YWY7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQC6/entry#A0A8V0YWY7-1", "sequence": { "sequence": "MEEARMRKLEAGRAKFAHFRERKAKSNVTQSQKKTTKRKGSSVHTHDVPQEEHAAMGQGCDVGKGIESKAEDTNFLETTTETEKVAVHSAAEYSELDDKMRQTRIAELEKRLLEKQQAVGRLTVQMNELQEQLSQHRDSMQLQETTIQEQNEVIRKLTSCLQQTRKDWDDLQEEASHVADQIHGLQLQLHEVNVMLKSKGSGKKEVLEAQQQMSLFQSSLQEQNARLEMLHQRAYDLEVQLESSQKNTKDKECLLAPTEEGMKDTIQQLYESVGEKGDCIKSLQDLLASERFNLSILQRSLSLRDSEIKELKNEITLTKMKEQQHIEELKVNHEKDVCRQIEHLKVELEKCHRKETAEANQIYEEEMILKYKSEPGQLKKELTALNSEERIQNLNRIIINLNNSLHESEISKENLRKELVNQQENFQREKTEVEMQYKVLINDLKSQLSKAKEQVKEAQRYEQEKQCLNEEIQKLHYFIRELNKKRLFEAEKSKDAKQKHDEETVSNKNLREIRTLPDILELQTMKLEKMLNEPHRFKEELDPDKLDFQCQLRIDSVRDESEEIVCSKIREHNESSGDHLYEEPLPELGFFTTDEEILSKYLVFTERPEQSYVSGCSEGYTIEEDKHSRSGLDSNVFSDPSTDFKPPQLNFDLDEKTCHWSLTKETFEETKMEAEALISFLSDGSPLQNKISDYGDVKDDERACVLERCVKLTEQLHKKESALKKSHQETQEAVEKWKKVMAELCEINVELNKEREARLCCEEQLLQKTEREKELENKINLLVKQKDEDGSQSSSVTEPIAQASKSSTWQQMVKDLQEERQKSSAWQEMVKELQEEKEMLMVQLRTQEQLVKEVQEQKIASDSVTSEVQTLFGRQLAALQSQRDRMQNQLDAQKAKNQRITELLGQKTILEETMLKEQALLKAEINNKEQDLALLVKEKTVLGERLSVMEEDLGKAERALAANASIIADLEKNIHEVNAEVQNVKEVQECERLSYEDRLNLNNREINKLHAEIKAKSTEFGEKESQLIEEIAHLKKVHLELENYLRESFQSVQDAKKAQCEMMNYYKEEIVKMESQHLAELTKLSLTHKKEIEELNAEIKDKVEKQKKLEEERVEQLALVKKVHEREHDREISELIAKHKEEMEELRAELHKEKLHLLDELQQQMAATHKAEIEYAQLQSQTLHSLELEALRLSLNNLHTSQLELTQSNLRKEKETALVELREMLNDKRAQEIAILQSRHQLEWEKIKERCLKEKEDLTSKYQQELVDQRKKIELEMEEKHIQILETLKRDWELESEMRLKYTCEELSKKHKAEIAELQKTLEMELEKVKAELGLLSLEKEQSEMKCVDLEKQQQLAITTLTKQLQSEHNQLLEDVKIESQEKEQNLQKELEKLQVMHEEFKTRSQEEVKQLWSQLGSTRANRQELSGGESVWLRMEAHVPELKEQLMARASQVEEIEHLKQKFEEQQQQTKSEHEAELEQLRIYFERKLRVTEENYREELTLLHQKLQELKEYSVSGVDVSHNQAGNISSSVIVFGEAVEKERKDFFLDQLNQQLEQHKEEIACLQGQLKEDHRHELDSLKSSLALQYKGDLLKMKMELSDKYIAEIEEMKRKHCLELEQLRARLSEEHIKEITKLRLQSAQDAARQVEMEVAKRVSVLEEEHKVKLSLLHSEEQHIAELSEEIKCLKEEMTKQKDFFVQNEKHLKEQMEQVKFKIAEDHENELKEAREEVLKIETLYKEKEKKWKCESEDQRVQAEEKLSLLHTELQNRLEYEKQNLQKEFEVREAQMNQLQDHQAAKIVELEKLVKEQQNNLKQLEDSLAVAQATRKSQEQYDSDLQAAKELMAKEMEKAELCLQEECALKLMKAQNKFMEEHKALTQKFTAEQEILLQELKKRHVDELELQSQQLQEKHKQEILSLTAEFQRKHQAEIKTLKSTLESKQQIQLEAFVAELQTKHQAQVDALEAKHLSNLDSLESSYLSEIQNIRGEHRLVLEKLQLHHTEQLHEKDKMNQACLAQEIEILKLKHSEELQLAQNNLKIELATVHMEKLKIMAVEAEEAHKDDLKAALQNQRSLLEEEKRLALDMLREEVVHMEEKHRKALQELQDLHEAEIKKHKEEYSRELEKELEKLKAQHKHEQEMYASASASEIETVRTALLSQFEAVKMKQQLQFQEEIELLKCQSEVLLEQQIAQLKDEFEAEKTALIHDQEQVLIQESEKAQAACQKEKETLSAQLQEKAARIIQLEKRVESLNCEIQETNCELETLIERRDRENQEGGNLVAMLRSDIEQSKDERKKMQDSYQCVLKWLVELVKATIAVEDLICSKIGLCLDNSMASADSMESHSIVEEIGFAQYFKAKEKSHLEKVDELLDETLTEHSQLSPVTEEQYELSQYLYESVFAKPEMAYENEEMILKICRRLRTAVERLLELVTESTKQLEKTHEIHAQFEEEFTRRNQETAQVVCQHRELMECLTEESEAKNQLALELHKAEGIIEGYVAEKAALEEALNLKEESERRLVVELENMRERFQELTQEQAILGLLKEVELLAKEKLELECQAEKDHSNLRSQMKVLEMELEEQLHSNQDLTKQLMETAELKQQIEVLEKQLKNQRQFMDEQAIERENERDDFQQEIKKLEEQLKLSAKLQTSGEPREYGVESLQAEVEEKVDDYNKLLLEKEQKHQEIAARDKEIEKLVAQVQELEHSSTEVSKTVNYLQQQLQKMKKVETELKQDKEALQQQQYNNLIQISALQSKLDEVRHGVPVEGTSDQELKEQLQAEQESLERKEGEIASLLDHLEQHKDILTSKNEEILQLKLQLEVQKNLSTSTINQLQIENAQLKDLAKLHVKQNRDSDVGDSSALSFPQALLEEKNQEIDHLNEQLRRLKYDQVNTLENKVVEDQKSEIEELRSVIEYLRGDQERLCKDKDEEVEQLHEVIEKLQKELAQIGPVCHEVSDNQGDIFQFGLEKSVENLQKELKKGLIDCQGDTDLDGRNALLLCKVRELEEDLEFASAAKKDLQQQLEEKESQFKMEVEILEKKCQNLQESSRQHFAELNTLRLQYHALQEEYSLLQTHISQRELEARIASSCVQELKDSMKEREVSILGKDSQIQAMAHQREADEGELRYLTEQASDLETELKKRDASQAQDVHSPELEVSRLDLHVQAMNQKEVSKQREIDELQGSTTKLKDQIKIYTKELEALHLERDELISQLELYKPKEQCDKENANCLELFCWGQRQGEVLKEGMEELESLETHVDQSFASPADNLEKVALFDFTAHDISKQSQVKQSEENISIQKLDMINSSEEQQTLKKHHHQTLDSPKIIVNAGCTEGTLKNFQDFIVDVTSWDSPEIMRKQDISMELPPALNLTPFSEAESTGLEMAHSRSSLQGDNSVLLGFSHLYENGSEEAAGRADVKSPVSSESIYSGADRDQDLKKTTLMSGTDNLTPSDLQDDVRSGASAIDVMSNGCDSSTRSNLEAKLKEQLQTSDHSDANFMAYLQYCGMFPDIMESVREKEILSPQLKTVLKLVYEESHKILALSEHSFGFRELKNVHQTKALMEGWQKEGLALLNAIQSLKDYLSKVADRGDKEEQRQMVVEHLFSSDRNSLLSEIQELRAQLRMTHLQNQEKLQQLQETLTSVEDHGSKQEHQLRRKVELLEYKLQQEKCIVSDLHSTLSEEQKRASETRELLSQEKAAVSTLKSDLYERKQENERLKKSLEEHQREINKLCFELESKEKDLTATLQELEAERLTETELRVLLEEQQLQHKKAEDEKKKALEDLQAALDLQTAQNRKLSVSLEHEQIINDNLRKELRIEYSRCEALLSQEHDKVLELQKNLDAERNRSLELLNSLNHERILTEQLSVQAKEDASCQRRELLLEQAFIRELQAQLEEERSQKTELAVITEKTHQRAIRSKRQLEAEVQMCCEETQKEKEITNKLRVMLDSLQSQKQEQNLELQHQRDEQRIKEMQEIVAILGETERSPPSPSSQQGLLCTSDKDQNAKEPMTIEIGKFNLQQQQKQQLEKIRQQLLFVAAHLIELMCKTVDKTVNDWYVSNDEAVASLLQTLKELKSDLLSPASQIRSTDDSNPVQELERAAWQQERNILQNALKQAESKLAKATAETENKPAMEAFNPKLQRLYRKYLRAESFRKALVYQKKYLLLLLGGFQDCEQATLSLIARMGIYPSPADLQLSASRSRPFTKFRCAVRAVIAVSRLKFLVKKWNKLNRKNAQAETVSQNTGSNTDCLHPLQKSHLCLLRILNDHLQNISTAWRLSSKD", "length": 4280, "header": "tr|A0A8V0YWY7-1|A0A8V0YWY7_CHICK Computationally mapped isoform of Pericentrin OS=Gallus gallus OX=9031 GN=PCNT PE=4 SV=1 CANONICAL=A0A8V0YQC6-1" }, "locus": { "chromosome": "7", "start_pos": 7180631, "end_pos": 7085410, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010035877.1", "url": "https://www.ensembl.org/id/ENSGALT00010035877.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020812.1", "url": "https://www.ensembl.org/id/ENSGALP00010020812.1" } ] } }, { "isoform_ac": "A0A8V0YX40-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQC6/entry#A0A8V0YX40-1", "sequence": { "sequence": "MEEARMRKLEAGRAKFAHFRERKAKSNVTQSQKKTTKRKGSSVHTHDVPQEEHAAMGQGCDVGKGIESKAEDTNFLETTTETEKVAVHSAAEYSELDDKMRQTRIAELEKRLLEKQQAVGRLTVQMNELQEQLSQHRDSMQLQETTIQEQNEVIRKLTSCLQQTRKDWDDLQEEASHVADQIHGLQLQLHEVNVMLKSKGSGKKEVLEAQQQMSLFQSSLQEQNARLEMLHQRAYDLEVQLESSQKVHEREHDREISELIAKHKEEMEELRAELHKEKLHLLDELQQQMAATHKAEIEYAQLQSQTLHSLELEALRLSLNNLHTSQLELTQSNLRKEKETALVELREMLNDKRAQEIAILQSRHQLEWEKIKERCLKEKEDLTSKYQQELVDQRKKIELEMEEKHIQILETLKRDWELESEMRLKYTCEELSKKHKAEIAELQKTLEMELEKVKAELGLLSLEKEQSEMKCVDLEKQQQLAITTLTKQLQSEHNQLLEDVKIESQEKEQNLQKELEKLQVMHEEFKTRSQEEVKQLWSQLGSTRANRQELSGGESVWLRMEAHVPELKEQLMARASQVEEIEHLKQKFEEQQQQTKSEHEAELEQLRIYFERKLRVTEENYREELTLLHQKLQELKEYSVSGVDVSHNQAGNISSSVIVFGEAVEKERKDFFLDQLNQQLEQHKEEIACLQGQLKEDHRHELDSLKSSLALQYKGDLLKMKMELSDKYIAEIEEMKRKHCLELEQLRARLSEEHIKEITKLRLQSAQDAARQVEMEVAKRVSVLEEEHKVKLSLLHSEEQHIAELSEEIKCLKEEMTKQKDFFVQNEKHLKEQMEQVKFKIAEDHENELKEAREEVLKIETLYKEKEKKWKCESEDQRVQAEEKLSLLHTELQNRLEYEKQNLQKEFEVREAQMNQLQDHQAAKIVELEKLVKEQQNNLKQLEDSLAVAQATRKSQEQYDSDLQAAKELMAKEMEKAELCLQEECALKLMKAQNKFMEEHKALTQKFTAEQEILLQELKKRHVDELELQSQQLQEKHKQEILSLTAEFQRKHQAEIKTLKSTLESKQQIQLEAFVAELQTKHQAQVDALEAKHLSNLDSLESSYLSEIQNIRGEHRLVLEKLQLHHTEQLHEKDKMNQACLAQEIEILKLKHSEELQLAQNNLKIELATVHMEKLKIMAVEAEEAHKDDLKAALQNQRSLLEEEKRLALDMLREEVVHMEEKHRKALQELQDLHEAEIKKHKEEYSRELEKELEKLKAQHKHEQEMYASASASEIETVRTALLSQFEAVKMKQQLQFQEEIELLKCQSEVLLEQQIAQLKDEFEAEKTALIHDQEQVLIQESEKAQAACQKEKETLSAQLQEKAARIIQLEKRVESLNCEIQETNCELETLIERRDRENQEGGNLVAMLRSDIEQSKDERKKMQDSYQCVLKWLVELVKATIAVEDLICSKIGLCLDNSMASADSMESHSIVEEIGFAQYFKAKEKSHLEKDELLDETLTEHSQLSPVTEEQYELSQYLYESVFAKPEMAYENEEMILKICRRLRTAVERLLELVTESTKQLEKTHEIHAQFEEEFTRRNQETAQVVCQHRELMECLTEESEAKNQLALELHKAEGIIEGYVAEKAALEEALNLKEESERRLVVELENMRERFQELTQEQAILGLLKEVELLAKEKLELECQAEKDHSNLRSQMKVLEMELEEQLHSNQDLTKQLMETAELKQQIEVLEKQLKNQRQFMDEQAIERENERDDFQQEIKKLEEQLKLSAKLQTSGEPREYGNYDLILQVESLQAEVEEKVDDYNKLLLEKEQKHQEIAARDKEIEKLVAQVQELEHSSTEVSKTVNYLQQQLQKMKKVETELKQDKEALQQQQYNNLIQISALQSKLDEVRHGVPVEGTSDQELKEQLQAEQESLERKEGEIASLLDHLEQHKDILTSKNEEILQLKLQLEVQKNLSTSTINQLQIENAQLKDLAKLHVKQNRDSDVGDSSALSFPQALLEEKNQEIDHLNEQLRRLKYDQVNTLENKVVEDQKSEIEELRSVIEYLRGDQERLCKDKDEEVEQLHEVIEKLQKELAQIGPVCHEVSDNQGDIFQFGLEKSVENLQKELKKGLIDCQGDTDLDGRNALLLCKVRELEEDLEFASAAKKDLQQQLEEKESQFKMEVEILEKKCQNLQESSRQHFAELNTLRLQYHALQEEYSLLQTHISQRELEARIASSCVQELKDSMKEREVSILGKDSQIQAMAHQREADEGELRYLTEQASDLETELKKRDASQAQDVHSPELEVSRLDLHVQAMNQKEVSKQREIDELQGSTTKLKDQIKIYTKELEALHLERDELISQLELYKPKEQCDKENANCLELFCWGQRQGEVLKEGMEELESLETHVDQSFASPADNLEKVALFDFTAHDISKQSQVKQSEENISIQKLDMINSSEEQQTLKKHHHQTLDSPKIIVNAGCTEGTLKNFQDFIVDVTSWDSPEIMRKQDISMELPPALNLTPFSEAESTGLEMAHSRSSLQGDNSVLLGFSHLYENGSEEAAGRADVKSPVSSESIYSGADRDQDLKKTTLMSGTDNLTPSDLQDDVRSGASAIDVMSNGCDSSTRSNLEAKLKEQLQTSDHSDANFMAYLQYCGMFPDIMESVREKEILSPQLKTVLKLVYEESHKILALSEHSFGFRELKNVHQTKALMEGWQKEGLALLNAIQSLKDYLSKVADRGDKEEQRQMVVEHLFSSDRNSLLSEIQELRAQLRMTHLQNQEKLQQLQETLTSVEDHGSKQEHQLRRKVELLEYKLQQEKCIVSDLHSTLSEEQKRASETRELLSQEKAAVSTLKSDLYERKQENERLKKSLEEHQREINKLCFELESKEKDLTATLQELEAERLTETELRVLLEEQQLQHKKAEDEKKKALEDLQAALDLQTAQNRKLSVSLEHEQIINDNLRKELRIEYSRCEALLSQEHDKVLELQKNLDAERNRSLELLNSLNHERILTEQLSVQAKEDASCQRRELLLEQAFIRELQAQLEEERSQKTELAVITEKTHQRAIRSKRQLEAEVQMCCEETQKEKEITNKLRVMLDSLQSQKQEQNLELQHQRDEQRIKEMQEIVAILGETERSPPSPSSQQGLLCTSDKDQNAKEPMTIEIGKFNLQQQQKQQLEKIRQQLLFVAAHLIELMCKTVDKTVNDWYVSNDEAVASLLQTLKELKSDLLSPASQIRSTDDSNPVQELERAAWQQERNILQNALKQAESKLAKATAETENKPAMEAFNPKLQRLYRKYLRAESFRKALVYQKKYLLLLLGGFQDCEQATLSLIARMGIYPSPADLQLSASRSRPFTKFRCAVRAVIAVSRLKFLVKKWNKLNRKNAQAETVSQNTGSNTASGARTETLKQQQLTAVHVSSPPTWDTGLCHRTSSARSVSCSSKSSLRSHSRLPPSTSEKSPVPTQDPERSLTEYIHRLEIIQQRLGGMQPGQVPGPPCQRNMKK", "length": 3481, "header": "tr|A0A8V0YX40-1|A0A8V0YX40_CHICK Computationally mapped isoform of Pericentrin OS=Gallus gallus OX=9031 GN=PCNT PE=4 SV=1 CANONICAL=A0A8V0YQC6-1" }, "locus": { "chromosome": "7", "start_pos": 7180631, "end_pos": 7083087, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010035948.1", "url": "https://www.ensembl.org/id/ENSGALT00010035948.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020867.1", "url": "https://www.ensembl.org/id/ENSGALP00010020867.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-2565942", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2565942", "resource": "Reactome", "description": "Regulation of PLK1 Activity at G2/M Transition" }, { "id": "R-GGA-380259", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-380259", "resource": "Reactome", "description": "Loss of Nlp from mitotic centrosomes" }, { "id": "R-GGA-380270", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-380270", "resource": "Reactome", "description": "Recruitment of mitotic centrosome proteins and complexes" }, { "id": "R-GGA-380284", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-380284", "resource": "Reactome", "description": "Loss of proteins required for interphase microtubule organization from the centrosome" }, { "id": "R-GGA-380320", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-380320", "resource": "Reactome", "description": "Recruitment of NuMA to mitotic centrosomes" }, { "id": "R-GGA-5620912", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5620912", "resource": "Reactome", "description": "Anchoring of the basal body to the plasma membrane" }, { "id": "R-GGA-8854518", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8854518", "resource": "Reactome", "description": "AURKA Activation by TPX2" }, { "id": "R-GGA-9646399", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9646399", "resource": "Reactome", "description": "Aggrephagy" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "molecular adaptor activity", "id": "GO:0060090", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060090", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQC6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQC6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQC6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQC6" } ], "pmid": "" }, { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQC6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQC6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQC6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQC6" } ], "pmid": "" }, { "name": "microtubule nucleation", "id": "GO:0007020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQC6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQC6" } ], "pmid": "" }, { "name": "mitotic spindle organization", "id": "GO:0007052", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007052", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQC6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQC6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1514, "end_pos": 1516, "annotation": "n_glycosylation_sequon" }, { "start_pos": 27, "end_pos": 29, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2817, "end_pos": 2819, "annotation": "n_glycosylation_sequon" }, { "start_pos": 293, "end_pos": 295, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3286, "end_pos": 3288, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3296, "end_pos": 3298, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3361, "end_pos": 3363, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3398, "end_pos": 3400, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3439, "end_pos": 3441, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3837, "end_pos": 3839, "annotation": "n_glycosylation_sequon" }, { "start_pos": 402, "end_pos": 404, "annotation": "n_glycosylation_sequon" }, { "start_pos": 573, "end_pos": 575, "annotation": "n_glycosylation_sequon" }, { "start_pos": 963, "end_pos": 965, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YQC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQC6" }, { "id": "PF10495", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10495" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Pericentrin/AKAP-450 centrosomal targeting", "eco_id": "ECO_0000259", "start_pos": 4137, "end_pos": 4218, "start_aa": "Lys", "end_aa": "Trp", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1514, "end_pos": 1516 }, { "start_pos": 27, "end_pos": 29 }, { 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"A0A8V0YQ92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ92/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQ92", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ92" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CIMIP1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ92", "locus": { "chromosome": "20", "start_pos": 11613663, "end_pos": 11618666, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010014923", "url": "https://www.ensembl.org/id/ENSGALG00010014923" } ] } } ], "crossref": [ { "id": "A0A8V0YQ92", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YQ92", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR020339", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020339", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YIU6", "url": "https://www.orthodb.org/?gene=A0A8V0YIU6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YQ92", "url": "https://www.orthodb.org/?gene=A0A8V0YQ92", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31909", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31909", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31909:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31909:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF14945", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14945", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YIU6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIU6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YIU6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIU6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQ92", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ92", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQ92-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ92-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "GSSYGSWRTALQAESAARSSAVCGAGGPPRASATRSFPLSAPGRRRAHHRPATVAARDPSRRGNGRAAQRRGRGQLKRYVESELETARRWSHKWGFLKAALEELIEDEKKEKTKPTIQLPEHLRIRPVTPVEKYIKVNPSPPVPKTSQGFIGWRSAVPELQLEHCFQIQSCKGAFFKDLKWPREPSD", "length": 187, "header": "tr|A0A8V0YQ92-1|A0A8V0YQ92_CHICK Isoform 1 of Ciliary microtubule inner protein 1 OS=Gallus gallus OX=9031 GN=CIMIP1 PE=4 SV=1 CANONICAL=A0A8V0YQ92-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YIU6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ92/entry#A0A8V0YIU6-1", "sequence": { "sequence": "GRACEEEAAGVHQPFTCATKRYVESELETARRWSHKWGFLKAALEELIEDEKKEKTKPTIQLPEHLRIRPVTPVEKYIKVNPSPPVPKTSQGFIGWRSAVPELQLEHCFQIQSCKGAFFKDLKWPREPSD", "length": 130, "header": "tr|A0A8V0YIU6-1|A0A8V0YQ92_CHICK Computationally mapped isoform of Ciliary microtubule inner protein 1 OS=Gallus gallus OX=9031 GN=CIMIP1 PE=4 SV=1 CANONICAL=A0A8V0YQ92-1" }, "locus": { "chromosome": "20", "start_pos": 11618354, "end_pos": 11614295, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010035901.1", "url": "https://www.ensembl.org/id/ENSGALT00010035901.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020831.1", "url": "https://www.ensembl.org/id/ENSGALP00010020831.1" } ] } }, { "isoform_ac": "A0A8V0YQ92-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ92/entry#A0A8V0YQ92-1", "sequence": { "sequence": "GSSYGSWRTALQAESAARSSAVCGAGGPPRASATRSFPLSAPGRRRAHHRPATVAARDPSRRGNGRAAQRRGRGQLKRYVESELETARRWSHKWGFLKAALEELIEDEKKEKTKPTIQLPEHLRIRPVTPVEKYIKVNPSPPVPKTSQGFIGWRSAVPELQLEHCFQIQSCKGAFFKDLKWPREPSD", "length": 187, "header": "tr|A0A8V0YQ92-1|A0A8V0YQ92_CHICK Isoform 1 of Ciliary microtubule inner protein 1 OS=Gallus gallus OX=9031 GN=CIMIP1 PE=4 SV=1 CANONICAL=A0A8V0YQ92-1" }, "locus": { "chromosome": "20", "start_pos": 11618296, "end_pos": 11614295, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010035900.1", "url": "https://www.ensembl.org/id/ENSGALT00010035900.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020830.1", "url": "https://www.ensembl.org/id/ENSGALP00010020830.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cilium", "id": "GO:0005929", "url": 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"n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YQA8-1", "uniprot_ac": "A0A8V0YQA8", "uniprot_id": "A0A8V0YQA8_CHICK", "mass": { "chemical_mass": 77145.0, "monoisotopic_mass": 77145.0 }, "refseq": { "ac": "XP_003643063", "name": "MAM domain-containing protein 2 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003643063" }, "gene_names": [ { "name": "MAMDC2", "type": "recommended", "evidence": [ { "id": "A0A8V0YQA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQA8" } ] }, { "name": "MAMDC2", "type": "synonym", "evidence": [ { "id": "XP_003643063", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003643063" } ] } ], "protein_names": [ { "name": "MAM domain containing 2", "type": "synonym", "evidence": [ { "id": "A0A8V0YQA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQA8/entry#names_and_taxonomy" } ] }, { "name": "MAM domain-containing protein 2 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_003643063", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003643063" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052572.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_003643063.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003643063", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003643063" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQA8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQA8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MAMDC2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQA8", "locus": { "chromosome": "Z", "start_pos": 35559760, "end_pos": 35493956, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010014934", "url": "https://www.ensembl.org/id/ENSGALG00010014934" } ] } } ], "crossref": [ { "id": "A0A8V0YQA8", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YQA8", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd06263", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06263", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "427247", "url": "https://www.ncbi.nlm.nih.gov/gene/427247", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000998", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000998", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013320", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013320", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051560", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051560", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:427247", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427247", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YEEIWKI", "url": "https://omabrowser.org/oma/group/YEEIWKI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YIV5", "url": "https://www.orthodb.org/?gene=A0A8V0YIV5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YQA8", "url": "https://www.orthodb.org/?gene=A0A8V0YQA8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23282", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23282", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23282:SF101", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23282:SF101", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00629", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00629", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003643063", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003643063", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YIV5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YIV5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQA8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQA8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQA8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQA8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLRLCLLALHALRLARAAPLSPGSCAFEDSACGYEWDYAHLPWALHGEGHYISVDTSYEGEKAVLVSPDLYSEEWSCIRLIYQIATTSVTSLDPATLNLYMRKEGESFDSLLWSAKEPSDSWLIASLDLTNSTKKYKIVLEAELGQDKSASIAVFEIKITPGYCIECDFEENHLCGFVNRWNPNVNWFVGGGNIRNSQSILPKDHTLNNELGHYMYVDSVYVKHFQEVAQLISPKTTAPMSGCLSFYYQLKQESSIVFTLYLRDMSGFYEEIWKTDSASTGDWVLAEVDFSAPYPMEVVFEVAFNSAKGGYVALDDISFSPVYCSNQTGILFNPADAGCNFEEDLCNFYQDHKDVPGWSRVKVKRNVYRAGDHTTGFGYYLLANTKFTSQPGYIGRLYGPTLPGNLQFCLRFYYALYGFFKMSGTLAVYIFEENHVVQEKIWSVLDSPRGVWTQAEISFKKPMPCKVVFVSWCKSFWDCGLVALDDISLSLGSCQAADLLPPSPGECTFEKDECMFTQKKRGRGSWQRRRGPTPTSYTGPKGDHTTGVGYYMYIEASNMVYGQRAYLISRSLRGTSGKQCLTFFYHMYGAGTGLLSVYLKREGDDEDIPLWRRTGEQSISWLRAVIEYESGRNYQIIFEAIRGVSIRSDTAIDDILFQAGPCLEVEEIQFSSGYPDSLNEIEY", "length": 683, "header": "tr|A0A8V0YQA8-1|A0A8V0YQA8_CHICK Isoform 1 of MAM domain containing 2 OS=Gallus gallus OX=9031 GN=MAMDC2 PE=4 SV=1 CANONICAL=A0A8V0YQA8-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YIV5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQA8/entry#A0A8V0YIV5-1", "sequence": { "sequence": "MPGEVWQPEFTKGHYISVDTSYEGEKAVLVSPDLYSEEWSCIRLIYQIATTSVTSLDPATLNLYMRKEGESFDSLLWSAKEPSDSWLIASLDLTNSTKKYKIVLEAELGQDKSASIAVFEIKITPGYCIECDFEENHLCGFVNRWNPNVNWFVGGGNIRNSQSILPKDHTLNNELGHYMYVDSVYVKHFQEVAQLISPKTTAPMSGCLSFYYQLKQESSIVFTLYLRDMSGFYEEIWKTDSASTGDWVLAEVDFSAPYPMEVVFEVAFNSAKGGYVALDDISFSPVYCSNQTGILFNPADAGCNFEEDLCNFYQDHKDVPGWSRVKVKRNVYRAGDHTTGFGYYLLANTKFTSQPGYIGRLYGPTLPGNLQFCLRFYYALYGFFKMSGTLAVYIFEENHVVQEKIWSVLDSPRGVWTQAEISFKKPMPCKVVFVSWCKSFWDCGLVALDDISLSLGSCQAADLLPPSPGECTFEKDECMFTQKKRGRGSWQRRRGPTPTSYTGPKGDHTTGVGYYMYIEASNMVYGQRAYLISRSLRGTSGKQCLTFFYHMYGAGTGLLSVYLKREGDDEDIPLWRRTGEQSISWLRAVIEYESGRNYQIIFEAIRGVSIRSDTAIDDILFQAGPCLEVEEIQFSSGYPDSLNEIEY", "length": 647, "header": "tr|A0A8V0YIV5-1|A0A8V0YQA8_CHICK Computationally mapped isoform of MAM domain containing 2 OS=Gallus gallus OX=9031 GN=MAMDC2 PE=4 SV=1 CANONICAL=A0A8V0YQA8-1" }, "locus": { "chromosome": "Z", "start_pos": 35558910, "end_pos": 35521521, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010035918.1", "url": "https://www.ensembl.org/id/ENSGALT00010035918.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020841.1", "url": "https://www.ensembl.org/id/ENSGALP00010020841.1" } ] } }, { "isoform_ac": "A0A8V0YQA8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQA8/entry#A0A8V0YQA8-1", "sequence": { "sequence": "MLRLCLLALHALRLARAAPLSPGSCAFEDSACGYEWDYAHLPWALHGEGHYISVDTSYEGEKAVLVSPDLYSEEWSCIRLIYQIATTSVTSLDPATLNLYMRKEGESFDSLLWSAKEPSDSWLIASLDLTNSTKKYKIVLEAELGQDKSASIAVFEIKITPGYCIECDFEENHLCGFVNRWNPNVNWFVGGGNIRNSQSILPKDHTLNNELGHYMYVDSVYVKHFQEVAQLISPKTTAPMSGCLSFYYQLKQESSIVFTLYLRDMSGFYEEIWKTDSASTGDWVLAEVDFSAPYPMEVVFEVAFNSAKGGYVALDDISFSPVYCSNQTGILFNPADAGCNFEEDLCNFYQDHKDVPGWSRVKVKRNVYRAGDHTTGFGYYLLANTKFTSQPGYIGRLYGPTLPGNLQFCLRFYYALYGFFKMSGTLAVYIFEENHVVQEKIWSVLDSPRGVWTQAEISFKKPMPCKVVFVSWCKSFWDCGLVALDDISLSLGSCQAADLLPPSPGECTFEKDECMFTQKKRGRGSWQRRRGPTPTSYTGPKGDHTTGVGYYMYIEASNMVYGQRAYLISRSLRGTSGKQCLTFFYHMYGAGTGLLSVYLKREGDDEDIPLWRRTGEQSISWLRAVIEYESGRNYQIIFEAIRGVSIRSDTAIDDILFQAGPCLEVEEIQFSSGYPDSLNEIEY", "length": 683, "header": "tr|A0A8V0YQA8-1|A0A8V0YQA8_CHICK Isoform 1 of MAM domain containing 2 OS=Gallus gallus OX=9031 GN=MAMDC2 PE=4 SV=1 CANONICAL=A0A8V0YQA8-1" }, "locus": { "chromosome": "Z", "start_pos": 35558910, "end_pos": 35494111, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010035923.1", "url": "https://www.ensembl.org/id/ENSGALT00010035923.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020845.1", "url": "https://www.ensembl.org/id/ENSGALP00010020845.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 533, "start_aa": "Thr", "end_pos": 533, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr533", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:427247", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427247", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "F1M9P7-1", "protein_name": "MAM domain-containing protein 2", "gene_name": "Mamdc2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLLVGVLLVVQALLLANALDLPAGSCAFEEGTCGFDSVFAFLPWILNEEGHYVYVDTSFAKQGEKAVLLSSDLQAEEWNCLRLVYQITTPLGSVSEPSQLNLYVRFEDESFDRLLWSTKEPSDSWLIASLDLQNSSKKFKILIEGVLGQGNTASIALFEIKMTTGYCIDCDFEENHLCGFVNRWNPNVNWFVGGGTAKNTHSILPWDHTFRSEQGHYMYVDSVYVKHFQEVAQLISPMTTAPMSGCLSFYYQLQQGNDNVFSLYTRDMAGLYEEIWKVDSPGNAVWNLAEVEFSAPYPMEVIFEVAFNGPKGGYVALDDISFSPVHCQNQTGLPFSAVGTSCDFEKDLCNFYQDKEGPGWTRVRVKANMYRTGDHTTGTGHYLLANTKFTSQPGYIGRLYGPSLPGNMQYCVRFHYAIIGFLKMSDTLAVYIFEENHVVQEKIWSVLESPRGVWMQAEVSFKKPMPTKVVFMSLCKSFWDCGLVALDDITIQLGNCRSPERLPPPPGECTFDQDECAFTQEKRNRSSWHRGRGETPTSYTGPKGDHTTGVGYYMYIEASHMVYGQKAHLLSQPLRGVPGKHCLIFFYHMYGAGTGLLSVYLKREEDSKESLLWRRKGEQSISWLRALVEYSSRRQHQIIFEAIRGVSIRSDIAIDDVKFQAGPCEEMEDTSQQSSGYSEDLNEIDY", "length": 686 }, "evidence": [ { "id": "A0A8V0YQA8", "url": "https://omabrowser.org/oma/group/A0A8V0YQA8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q7Z304-1", "protein_name": "MAM domain-containing protein 2", "gene_name": "MAMDC2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLLRGVLLALQALQLAGALDLPAGSCAFEESTCGFDSVLASLPWILNEEGHYIYVDTSFGKQGEKAVLLSPDLQAEEWSCLRLVYQITTSSESLSDPSQLNLYMRFEDESFDRLLWSAKEPSDSWLIASLDLQNSSKKFKILIEGVLGQGNTASIALFEIKMTTGYCIECDFEENHLCGFVNRWNPNVNWFVGGGSIRNVHSILPQDHTFKSELGHYMYVDSVYVKHFQEVAQLISPLTTAPMAGCLSFYYQIQQGNDNVFSLYTRDVAGLYEEIWKADRPGNAAWNLAEVEFSAPYPMEVIFEVAFNGPKGGYVALDDISFSPVHCQNQTELLFSAVEASCNFEQDLCNFYQDKEGPGWTRVKVKPNMYRAGDHTTGLGYYLLANTKFTSQPGYIGRLYGPSLPGNLQYCLRFHYAIYGFLKMSDTLAVYIFEENHVVQEKIWSVLESPRGVWMQAEITFKKPMPTKVVFMSLCKSFWDCGLVALDDITIQLGSCSSSEKLPPPPGECTFEQDECTFTQEKRNRSSWHRRRGETPTSYTGPKGDHTTGVGYYMYIEASHMVYGQKARLLSRPLRGVSGKHCLTFFYHMYGGGTGLLSVYLKKEEDSEESLLWRRRGEQSISWLRALIEYSCERQHQIIFEAIRGVSIRSDIAIDDVKFQAGPCGEMEDTTQQSSGYSEDLNEIEY", "length": 686 }, "evidence": [ { "id": "A0A8V0YQA8", "url": "https://omabrowser.org/oma/group/A0A8V0YQA8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8CG85-1", "protein_name": "MAM domain-containing protein 2", "gene_name": "Mamdc2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLLEGVLLVVQALQLASALDLPAGSCAFEEDTCGFDSVFAFLPWILNEEGHYVYMDTSFARQGEKAVLLSSDLQAEEWNCLRLVYQITTPPGSVSDPSQLNLYVRFEDESFDRLLWSTKEPSDSWLIASLDLQNTSKKFKILIEGVLGQGNTASIALFEIKMTAGYCIECDFEENHLCGFVNRWNPNVNWFVGGGTAKNTHSVLPQDHTFRSEHGHYMYVDSVYVKHFQEVAQLISPVTTASMSGCLSFYYQLQQGNDNVFSVYTRDMAGLYEEIWKVDSPGNAAWNLAEVEFSAPYPMEVIFEVAFNGPKGGYVALDDISFSPVHCQNQTGLPFSAVETSCDFEIGLCNFYQDKEGPGWTRVRVKANMYRAGDHTTGTGHYLLANTKFTSQPGYIGRLYGPSLPGNMQYCVRFHYAIFGFLKMSDTLAVYIFEENHVVQEKIWSVLESPRGVWMQAEISFKKPMPTKVVFMSLCKSFWDCGLVALDDITIQLGNCRSPARLPPPPGECTFDQDECAFTQEKRNRSSWHRGRGETPTSYTGPKGDHTTGVGYYMYIEASHMVYGQKAHLLSQPLRGVPGKHCLTFFYHMYGAGTGLLSVYLKREEDSEESLLWRRRGEQSISWLRALVEYSCRRRHQIIFEATRGVSIRSDIAIDDVKLQAGPCAGMEDTTEQSSGYSEDLNEIEY", "length": 686 }, "evidence": [ { "id": "A0A8V0YQA8", "url": "https://omabrowser.org/oma/group/A0A8V0YQA8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQA8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQA8" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQA8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQA8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 131, "end_pos": 133, "annotation": "n_glycosylation_sequon" }, { "start_pos": 326, "end_pos": 328, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YQA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQA8" }, { "id": "PS50060", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50060" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "MAM", "eco_id": "ECO_0000259", "start_pos": 23, "end_pos": 166, "start_aa": "Gly", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 533 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 131, "end_pos": 133 }, { "start_pos": 326, "end_pos": 328 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YQJ4-1", "uniprot_ac": "A0A8V0YQJ4", "uniprot_id": "A0A8V0YQJ4_CHICK", "mass": { "chemical_mass": 26684.0, "monoisotopic_mass": 26684.0 }, "refseq": {}, "gene_names": [ { "name": "ARL15", "type": "recommended", "evidence": [ { "id": "A0A8V0YQJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQJ4" } ] } ], "protein_names": [ { "name": "ADP-ribosylation factor-like protein 15", "type": "recommended", "evidence": [ { "id": "A0A8V0YQJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQJ4/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQJ4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQJ4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ARL15", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQJ4", "locus": { "chromosome": "Z", "start_pos": 16735174, "end_pos": 16955040, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010014992", "url": "https://www.ensembl.org/id/ENSGALG00010014992" } ] } } ], "crossref": [ { "id": "A0A8V0YQJ4", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YQJ4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000014911", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000014911", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd04162", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04162", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "769515", "url": "https://www.ncbi.nlm.nih.gov/gene/769515", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006689", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006689", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042292", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042292", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:769515", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:769515", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "RLCCKGP", "url": "https://omabrowser.org/oma/group/RLCCKGP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5P8X0", "url": "https://www.orthodb.org/?gene=A0A1D5P8X0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YJ38", "url": "https://www.orthodb.org/?gene=A0A8V0YJ38", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YJ43", "url": "https://www.orthodb.org/?gene=A0A8V0YJ43", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YJ56", "url": "https://www.orthodb.org/?gene=A0A8V0YJ56", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YQI2", "url": "https://www.orthodb.org/?gene=A0A8V0YQI2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YQI5", "url": "https://www.orthodb.org/?gene=A0A8V0YQI5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YQJ4", "url": "https://www.orthodb.org/?gene=A0A8V0YQJ4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YS83", "url": "https://www.orthodb.org/?gene=A0A8V0YS83", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YX96", "url": "https://www.orthodb.org/?gene=A0A8V0YX96", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NMW9", "url": "https://www.orthodb.org/?gene=F1NMW9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46693", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46693", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46693:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46693:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00025", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00025", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A1D5P8X0", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P8X0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5P8X0-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P8X0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJ38", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ38", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJ38-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ38-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJ43", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ43", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJ43-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ43-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJ56", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ56", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJ56-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ56-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQI2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQI2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQI2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQI2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQI5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQI5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQI5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQI5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQJ4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQJ4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQJ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQJ4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YS83", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YS83", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YS83-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YS83-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YX96", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YX96", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YX96-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YX96-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NMW9", "url": "https://www.uniprot.org/uniprotkb/F1NMW9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NMW9-1", "url": "https://www.uniprot.org/uniprotkb/F1NMW9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "EDLWDFHFEAIKPPPALSRGTGLSHRAGPAGRCLLCHLCAALGPAPTSLNGESECFRALCCKGPPPPRPEYDLVCIGLTGSGKTSLLSQLCSESPENIVSTTGFSIKAVPFQNAILNVKELGGADNIRKYWSRYYQGSQGVIFVLDSASSEDDLETARNELHSALQHPQLCTLPFLILANHQDKPAARSVQEIKKYFELEPLARGKRWILKPCSLDDMEAVKDSFSLLINLLEERDFEPSRM", "length": 242, "header": "tr|A0A8V0YQJ4-1|A0A8V0YQJ4_CHICK Isoform 1 of ADP-ribosylation factor-like protein 15 OS=Gallus gallus OX=9031 GN=ARL15 PE=1 SV=1 CANONICAL=A0A8V0YQJ4-1" }, "isoforms": [ { "isoform_ac": "A0A1D5P8X0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQJ4/entry#A0A1D5P8X0-1", "sequence": { "sequence": "MDYLCFRALCCKGPPPPRPEYDLVCIGLTGSGKTSLLSQLCSESPENIVSTTGFSIKAVPFQNAILNVKELGGADNIRKYWSRYYQGSQGVIFVLDSASSEDDLETARNELHSALQHPQLCTLPFLILANHQDKPAARSVQEIKKYFELEPLARGKRWILKPCSLDDMEAVKDSFSLLINLLEERDFEPSRM", "length": 192, "header": "tr|A0A1D5P8X0-1|A0A1D5P8X0_CHICK Computationally mapped isoform of ADP-ribosylation factor-like protein 15 OS=Gallus gallus OX=9031 GN=ARL15 PE=1 SV=2 CANONICAL=A0A8V0YQJ4-1" }, "locus": { "chromosome": "Z", "start_pos": 16953982, "end_pos": 16743866, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010036071.1", "url": "https://www.ensembl.org/id/ENSGALT00010036071.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020947.1", "url": "https://www.ensembl.org/id/ENSGALP00010020947.1" } ] } }, { "isoform_ac": "A0A8V0YJ38-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQJ4/entry#A0A8V0YJ38-1", "sequence": { "sequence": "MSQQCALAAQKANGILGCIKRSMTRLRECFRALCCKGPPPPRPEYDLVCIGLTGSGKTSLLSQLCSESPENIVSTTGFSIKAVPFQNAILNVKELGGADNIRKYWSRYYQGSQGVIFVLDSASSEDDLETARNELHSALQHPQLCTLPFLILANHQDKPAARSVQEIKKYFELEPLARGKRWILKPCSLDDMEAVKDSFSLLINLLEERDFEPSRM", "length": 216, "header": "tr|A0A8V0YJ38-1|A0A8V0YQJ4_CHICK Computationally mapped isoform of ADP-ribosylation factor-like protein 15 OS=Gallus gallus OX=9031 GN=ARL15 PE=1 SV=1 CANONICAL=A0A8V0YQJ4-1" }, "locus": { "chromosome": "Z", "start_pos": 16929534, "end_pos": 16743866, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010036056.1", "url": "https://www.ensembl.org/id/ENSGALT00010036056.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020935.1", "url": "https://www.ensembl.org/id/ENSGALP00010020935.1" } ] } }, { "isoform_ac": "A0A8V0YJ43-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQJ4/entry#A0A8V0YJ43-1", "sequence": { "sequence": "MKCFRALCCKGPPPPRPEYDLVCIGLTGSGKTSLLSQLCSESPENIVSTTGFSIKAVPFQNAILNVKELGGADNIRKYWSRYYQGSQGVIFVLDSASSEDDLETARNELHSALQHPQLCTLPFLILANHQDKPAARSVQEIKKYFELEPLARGKRWILKPCSLDDMEAVKDSFSLLINLLEERDFEPSRM", "length": 190, "header": "tr|A0A8V0YJ43-1|A0A8V0YQJ4_CHICK Computationally mapped isoform of ADP-ribosylation factor-like protein 15 OS=Gallus gallus OX=9031 GN=ARL15 PE=1 SV=1 CANONICAL=A0A8V0YQJ4-1" }, "locus": { "chromosome": "Z", "start_pos": 16876404, "end_pos": 16743866, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010036061.1", "url": "https://www.ensembl.org/id/ENSGALT00010036061.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020940.1", "url": "https://www.ensembl.org/id/ENSGALP00010020940.1" } ] } }, { "isoform_ac": "A0A8V0YJ56-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQJ4/entry#A0A8V0YJ56-1", "sequence": { "sequence": "NWHLHATICCCGVCGFRTCPLIREGCSECFRALCCKGPPPPRPEYDLVCIGLTGSGKTSLLSQLCSESPENIVSTTGFSIKAVPFQNAILNVKELGGADNIRKYWSRYYQGSQGVIFVLDSASSEDDLETARNELHSALQHPQLCTLPFLILANHQDKPAARSVQEIKKYFELEPLARGKRWILKPCSLDDMEAVKDSFSLLINLLEERDFEPSRM", "length": 216, "header": "tr|A0A8V0YJ56-1|A0A8V0YQJ4_CHICK Computationally mapped isoform of ADP-ribosylation factor-like protein 15 OS=Gallus gallus OX=9031 GN=ARL15 PE=1 SV=1 CANONICAL=A0A8V0YQJ4-1" }, "locus": { "chromosome": "Z", "start_pos": 16939851, "end_pos": 16743866, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010036082.1", "url": "https://www.ensembl.org/id/ENSGALT00010036082.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020955.1", "url": "https://www.ensembl.org/id/ENSGALP00010020955.1" } ] } }, { "isoform_ac": "A0A8V0YQI2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQJ4/entry#A0A8V0YQI2-1", "sequence": { "sequence": "MTCCKVEKFAQCFRALCCKGPPPPRPEYDLVCIGLTGSGKTSLLSQLCSESPENIVSTTGFSIKAVPFQNAILNVKELGGADNIRKYWSRYYQGSQGVIFVLDSASSEDDLETARNELHSALQHPQLCTLPFLILANHQDKPAARSVQEIKKYFELEPLARGKRWILKPCSLDDMEAVKDSFSLLINLLEERDFEPSRM", "length": 199, "header": "tr|A0A8V0YQI2-1|A0A8V0YQI2_CHICK Computationally mapped isoform of ADP-ribosylation factor-like protein 15 OS=Gallus gallus OX=9031 GN=ARL15 PE=1 SV=1 CANONICAL=A0A8V0YQJ4-1" }, "locus": { "chromosome": "Z", "start_pos": 16932970, "end_pos": 16743866, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010036058.1", "url": "https://www.ensembl.org/id/ENSGALT00010036058.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020937.1", "url": "https://www.ensembl.org/id/ENSGALP00010020937.1" } ] } }, { "isoform_ac": "A0A8V0YQI5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQJ4/entry#A0A8V0YQI5-1", "sequence": { "sequence": "MSQVQPSEEKNIFTHLKTMSECIQLSFAVCRIGIYTCFRALCCKGPPPPRPEYDLVCIGLTGSGKTSLLSQLCSESPENIVSTTGFSIKAVPFQNAILNVKELGGADNIRKYWSRYYQGSQGVIFVLDSASSEDDLETARNELHSALQHPQLCTLPFLILANHQDKPAARSVQEIKKYFELEPLARGKRWILKPCSLDDMEAVKDSFSLLINLLEERDFEPSRM", "length": 224, "header": "tr|A0A8V0YQI5-1|A0A8V0YQI5_CHICK Computationally mapped isoform of ADP-ribosylation factor-like protein 15 OS=Gallus gallus OX=9031 GN=ARL15 PE=1 SV=1 CANONICAL=A0A8V0YQJ4-1" }, "locus": { "chromosome": "Z", "start_pos": 16951610, "end_pos": 16743866, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010036065.1", "url": "https://www.ensembl.org/id/ENSGALT00010036065.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020942.1", "url": "https://www.ensembl.org/id/ENSGALP00010020942.1" } ] } }, { "isoform_ac": "A0A8V0YQJ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQJ4/entry#A0A8V0YQJ4-1", "sequence": { "sequence": "EDLWDFHFEAIKPPPALSRGTGLSHRAGPAGRCLLCHLCAALGPAPTSLNGESECFRALCCKGPPPPRPEYDLVCIGLTGSGKTSLLSQLCSESPENIVSTTGFSIKAVPFQNAILNVKELGGADNIRKYWSRYYQGSQGVIFVLDSASSEDDLETARNELHSALQHPQLCTLPFLILANHQDKPAARSVQEIKKYFELEPLARGKRWILKPCSLDDMEAVKDSFSLLINLLEERDFEPSRM", "length": 242, "header": "tr|A0A8V0YQJ4-1|A0A8V0YQJ4_CHICK Isoform 1 of ADP-ribosylation factor-like protein 15 OS=Gallus gallus OX=9031 GN=ARL15 PE=1 SV=1 CANONICAL=A0A8V0YQJ4-1" }, "locus": { "chromosome": "Z", "start_pos": 16954841, "end_pos": 16743866, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010036078.1", "url": "https://www.ensembl.org/id/ENSGALT00010036078.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020952.1", "url": "https://www.ensembl.org/id/ENSGALP00010020952.1" } ] } }, { "isoform_ac": "A0A8V0YS83-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQJ4/entry#A0A8V0YS83-1", "sequence": { "sequence": "MWISESVSGDRPFLSVLCFRALCCKGPPPPRPEYDLVCIGLTGSGKTSLLSQLCSESPENIVSTTGFSIKAVPFQNAILNVKELGGADNIRKYWSRYYQGSQGVIFVLDSASSEDDLETARNELHSALQHPQLCTLPFLILANHQDKPAARSVQEIKKYFELEPLARGKRWILKPCSLDDMEAVKDSFSLLINLLEERDFEPSRM", "length": 205, "header": "tr|A0A8V0YS83-1|A0A8V0YS83_CHICK Computationally mapped isoform of ADP-ribosylation factor-like protein 15 OS=Gallus gallus OX=9031 GN=ARL15 PE=1 SV=1 CANONICAL=A0A8V0YQJ4-1" }, "locus": { "chromosome": "Z", "start_pos": 16921877, "end_pos": 16743866, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010036054.1", "url": "https://www.ensembl.org/id/ENSGALT00010036054.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020933.1", "url": "https://www.ensembl.org/id/ENSGALP00010020933.1" } ] } }, { "isoform_ac": "A0A8V0YX96-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQJ4/entry#A0A8V0YX96-1", "sequence": { "sequence": "MCFRALCCKGPPPPRPEYDLVCIGLTGSGKTSLLSQLCSESPENIVSTTGFSIKAVPFQNAILNVKELGGADNIRKYWSRYYQGSQGVIFVLDSASSEDDLETARNELHSALQHPQLCTLPFLILANHQDKPAARSVQEIKKYFELEPLARGKRWILKPCSLDDMEAVKDSFSLLINLLEERDFEPSRM", "length": 189, "header": "tr|A0A8V0YX96-1|A0A8V0YX96_CHICK Computationally mapped isoform of ADP-ribosylation factor-like protein 15 OS=Gallus gallus OX=9031 GN=ARL15 PE=1 SV=1 CANONICAL=A0A8V0YQJ4-1" }, "locus": { "chromosome": "Z", "start_pos": 16895994, "end_pos": 16743866, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010036051.1", "url": "https://www.ensembl.org/id/ENSGALT00010036051.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020931.1", "url": "https://www.ensembl.org/id/ENSGALP00010020931.1" } ] } }, { "isoform_ac": "F1NMW9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQJ4/entry#F1NMW9-1", "sequence": { "sequence": "MSECIQLSFAVCRIGIYTCFRALCCKGPPPPRPEYDLVCIGLTGSGKTSLLSQLCSESPENIVSTTGFSIKAVPFQNAILNVKELGGADNIRKYWSRYYQGSQGVIFVLDSASSEDDLETARNELHSALQHPQLCTLPFLILANHQDKPAARSVQEIKKYFELEPLARGKRWILKPCSLDDMEAVKDSFSLLINLLEERDFEPSRM", "length": 206, "header": "tr|F1NMW9-1|F1NMW9_CHICK Computationally mapped isoform of ADP-ribosylation factor-like protein 15 OS=Gallus gallus OX=9031 GN=ARL15 PE=1 SV=2 CANONICAL=A0A8V0YQJ4-1" }, "locus": { "chromosome": "Z", "start_pos": 16939889, "end_pos": 16743866, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010036075.1", "url": "https://www.ensembl.org/id/ENSGALT00010036075.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020950.1", "url": "https://www.ensembl.org/id/ENSGALP00010020950.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:769515", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:769515", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2MRA8-1", "protein_name": "ADP-ribosylation factor-like protein 15", "gene_name": "Arl15", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSDLRITEAFLYMDYLCFRALCCKGPPPARPEYDLVCIGLTGSGKSSLLSKLCSESPDNVVSTTGFSIKAVPFQNAILNVKELGGADNIRKYWSRYYQGSQGVIFVLDSASSEDDLETARNELHSALQHPQLCTLPFLILANHQDKPAARSVQEIKKYFELEPLARGKRWILQPCSLDDMNALKDSFSQLINLLEEKDLEAVRM", "length": 204 }, "evidence": [ { "id": "A0A8V0YQJ4", "url": "https://omabrowser.org/oma/group/A0A8V0YQJ4/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0ABK0LJG8-1", "protein_name": "ADP-ribosylation factor-like protein 15", "gene_name": "Arl15", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLPFGLYLMIYAVCSRPTVSHVFLIGVKLKRFFFSFLVAGKCTQLKTINHLDSMLHLNCDSGRKSRMTTCFRALCCKGPPPARPEYDLVCIGLTGSGKTSLLSKLCSESPENVVSTTGFSIKAVPFQNAVLNVKELGGADNIRKYWSRYYQGSQGVIFVLDSASSEDDLETARNELHSALQHPQLCTLPFLILANHQDKPAARSVQEIKKYFELEPLARGKRWILQPCSLDDVDALKDSFSQLINLLEEKDHEAMRM", "length": 257 }, "evidence": [ { "id": "A0A8V0YQJ4", "url": "https://omabrowser.org/oma/group/A0A8V0YQJ4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1RDR4-1", "protein_name": "ADP-ribosylation factor-like protein 15", "gene_name": "arl15b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MYWKPKAFYQDLFYLHNRAWDLQRRKRSTELTLLASRFIQILFLTSERRGVLSQSREKKSRLWMHSINGSVSFHSRLDSGILFSGENSKKLSRNYMDYLCFRTLCCKGPPPPRPEYDVVCIGLTGSGKTSLLSRLCSEATDNIVPTTGFSIKAVPFQNAILNVKELGGADSIKKYWSRYYQGSQGVVFVLDSASSEEDLEVARTELHSALQHPQLCTLPFLILANHQDKPAARSVQEIKKYFELEPLARGKSWILEGSTVDNMTAVKESFAQLIHLLEEKDQETGRI", "length": 287 }, "evidence": [ { "id": "A0A8V0YQJ4", "url": "https://omabrowser.org/oma/group/A0A8V0YQJ4/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q8BGR6-1", "protein_name": "ADP-ribosylation factor-like protein 15", "gene_name": "Arl15", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSDLRITEAFLYMDYLCFRALCCKGPPPARPEYDLVCIGLTGSGKTSLLSELCSESPENVVSTTGFSIKAVPFQNAVLNVKELGGADNIRKYWSRYYQGSQGVIFVLDSASSEDDLETARNELHSALQHPQLCTLPFLILANHQDKPAARSVQEIKKYFELEPLARGKRWILQPCSLDDVDTLKDSFSQLINLLEEKDHEAVRM", "length": 204 }, "evidence": [ { "id": "A0A8V0YQJ4", "url": "https://omabrowser.org/oma/group/A0A8V0YQJ4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "GTPase activity", "id": "GO:0003924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003924", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQJ4", "url": 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"https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03875", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR007484", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007484", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045175", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045175", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR053973", "url": "https://www.ebi.ac.uk/interpro/entry/IPR053973", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR053974", "url": "https://www.ebi.ac.uk/interpro/entry/IPR053974", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YJH8", "url": "https://www.orthodb.org/?gene=A0A8V0YJH8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YPC4", "url": "https://www.orthodb.org/?gene=A0A8V0YPC4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12147", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12147", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12147:SF22", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12147:SF22", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04389", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04389", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF22248", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22248", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF22249", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22249", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YJH8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJH8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJH8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJH8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YPC4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPC4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YPC4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPC4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLEILYTLSKSSEPLQHAVIFLFNGAEENILQASHGFITQHEWAKSIRAFINLEAAGVGGKELVFQTGPENPWLVQAYVFAAKHPFASVVAQEIFQSGIIPADTDFRIYRDFGNVPGIDLAFIENGYIYHTKYDTSDRILTDSIQRAGDNILAVLKYLATSDMLPKSFEYRHGNVVFFDVLGLFVLAYPARVGTIMNYIIAAIAFLYLAKKVLQPKNKAINNLKKFFTAFGLILLSWISTLVTVLIVAVFISLIGRSLSWYTHFYVSVFLYGTAAVVKLIIVHSLAKKFYYKNMNDQYLGDVFFDASLMIWSIVLAMITHIGLCSAFICTLWVAFPLLTKLMIHKEFRQKGATMKFVLMYMLGMFVPYLYMMYLNWTVFEMFTPIMGRSGSEIPPDVVLAGFIVASTMILSSYFINFIYLVKSTKTTLITLTAVFVVTLILVCSGIFFPYSSDAANPKPKRVFLQHINRRFHDLDGNLVKSDSGIWINGFDYNGISHITPYVPEINDTIRTPCEEWAPFCGLPWILPVHFMFRKNWYLPASEIFPASPIHFKVLTKELTPWNSVRLSFEISGPSHMSLYIRPREGSALSTWSLGDGTPVASVGGDYFVFYSHGLQATPWQFWIELTASEKHSDGIVSLAIAAHYFFGEDQKSPQLYALLERFPNWTFSSGWSCTYDLFVF", "length": 680, "header": "tr|A0A8V0YPC4-1|A0A8V0YPC4_CHICK Isoform 1 of Endoplasmic reticulum metallopeptidase 1 OS=Gallus gallus OX=9031 GN=ERMP1 PE=1 SV=1 CANONICAL=A0A8V0YPC4-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YJH8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPC4/entry#A0A8V0YJH8-1", "sequence": { "sequence": "MEKILFDLFQKEINFIYLVKSTKTTLITLTAVFVVTLILVCSGIFFPYSSDAANPKPKRVFLQHINRRFHDLDGNLVKSDSGIWINGFDYNGISHITPYVPEINDTIRTPCEEWAPFCGLPWILPVHFMFRKNWYLPASEIFPASPIHFKVLTKELTPWNSVRLSFEISGPSHMSLYIRPREGSALSTWSLGDGTPVASVGGDYFVFYSHGLQATPWQFWIELTASEKHSDGIVSLAIAAHYFFGEDQKSPQLYALLERFPNWTFSSGWSCTYDLFVF", "length": 278, "header": "tr|A0A8V0YJH8-1|A0A8V0YPC4_CHICK Computationally mapped isoform of Endoplasmic reticulum metallopeptidase 1 OS=Gallus gallus OX=9031 GN=ERMP1 PE=1 SV=1 CANONICAL=A0A8V0YPC4-1" }, "locus": { "chromosome": "Z", "start_pos": 28191618, "end_pos": 28187635, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030970.1", "url": "https://www.ensembl.org/id/ENSGALT00010030970.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017994.1", "url": "https://www.ensembl.org/id/ENSGALP00010017994.1" } ] } }, { "isoform_ac": "A0A8V0YPC4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPC4/entry#A0A8V0YPC4-1", "sequence": { "sequence": "MLEILYTLSKSSEPLQHAVIFLFNGAEENILQASHGFITQHEWAKSIRAFINLEAAGVGGKELVFQTGPENPWLVQAYVFAAKHPFASVVAQEIFQSGIIPADTDFRIYRDFGNVPGIDLAFIENGYIYHTKYDTSDRILTDSIQRAGDNILAVLKYLATSDMLPKSFEYRHGNVVFFDVLGLFVLAYPARVGTIMNYIIAAIAFLYLAKKVLQPKNKAINNLKKFFTAFGLILLSWISTLVTVLIVAVFISLIGRSLSWYTHFYVSVFLYGTAAVVKLIIVHSLAKKFYYKNMNDQYLGDVFFDASLMIWSIVLAMITHIGLCSAFICTLWVAFPLLTKLMIHKEFRQKGATMKFVLMYMLGMFVPYLYMMYLNWTVFEMFTPIMGRSGSEIPPDVVLAGFIVASTMILSSYFINFIYLVKSTKTTLITLTAVFVVTLILVCSGIFFPYSSDAANPKPKRVFLQHINRRFHDLDGNLVKSDSGIWINGFDYNGISHITPYVPEINDTIRTPCEEWAPFCGLPWILPVHFMFRKNWYLPASEIFPASPIHFKVLTKELTPWNSVRLSFEISGPSHMSLYIRPREGSALSTWSLGDGTPVASVGGDYFVFYSHGLQATPWQFWIELTASEKHSDGIVSLAIAAHYFFGEDQKSPQLYALLERFPNWTFSSGWSCTYDLFVF", "length": 680, "header": "tr|A0A8V0YPC4-1|A0A8V0YPC4_CHICK Isoform 1 of Endoplasmic reticulum metallopeptidase 1 OS=Gallus gallus OX=9031 GN=ERMP1 PE=1 SV=1 CANONICAL=A0A8V0YPC4-1" }, "locus": { "chromosome": "Z", "start_pos": 28198368, "end_pos": 28187635, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030973.1", "url": "https://www.ensembl.org/id/ENSGALT00010030973.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017997.1", "url": "https://www.ensembl.org/id/ENSGALP00010017997.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPC4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPC4" } ], "pmid": "" }, { "name": "cellular response to oxidative stress", "id": "GO:0034599", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034599", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPC4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPC4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPC4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPC4" } ], "pmid": "" }, { "name": "metalloexopeptidase activity", "id": "GO:0008235", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008235", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPC4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPC4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPC4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPC4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 375, "end_pos": 377, "annotation": "n_glycosylation_sequon" }, { "start_pos": 506, "end_pos": 508, "annotation": "n_glycosylation_sequon" }, { "start_pos": 664, "end_pos": 666, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YPC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPC4" }, { "id": "PF22248", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22248" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Endoplasmic reticulum metallopeptidase 1-like C-terminal", "eco_id": "ECO_0000259", "start_pos": 457, "end_pos": 678, "start_aa": "Pro", "end_aa": "Phe", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0YPC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPC4" }, { "id": "PF22249", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22249" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Endoplasmic reticulum metallopeptidase 1/1-A TM", "eco_id": "ECO_0000259", "start_pos": 223, "end_pos": 443, "start_aa": "Leu", "end_aa": "Cys", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0YPC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPC4" }, { "id": "PF04389", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04389" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Peptidase M28", "eco_id": "ECO_0000259", "start_pos": 1, "end_pos": 154, "start_aa": "Met", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 375, "end_pos": 377 }, { "start_pos": 506, "end_pos": 508 }, { "start_pos": 664, "end_pos": 666 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YR31-1", "uniprot_ac": "A0A8V0YR31", "uniprot_id": "A0A8V0YR31_CHICK", "mass": { "chemical_mass": 133699.0, "monoisotopic_mass": 133699.0 }, "refseq": { "ac": "XP_015141033", "name": "centrosomal protein of 135 kDa isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015141033" }, "gene_names": [ { "name": "CEP135", "type": "recommended", "evidence": [ { "id": "A0A8V0YR31", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YR31" } ] }, { "name": "CEP135", "type": "synonym", "evidence": [ { "id": "XP_015141033", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015141033" } ] } ], "protein_names": [ { "name": "Centrosomal protein 135", "type": "synonym", "evidence": [ { "id": "A0A8V0YR31", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YR31/entry#names_and_taxonomy" } ] }, { "name": "centrosomal protein of 135 kDa isoform X3", "type": "synonym", "evidence": [ { "id": "XP_015141033", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015141033" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052535.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015141033.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015141033", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015141033" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YR31", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YR31" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CEP135", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YR31", "locus": { "chromosome": "4", "start_pos": 64443846, "end_pos": 64474653, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010015083", "url": "https://www.ensembl.org/id/ENSGALG00010015083" } ] } } ], "crossref": [ { "id": "A0A8V0YR31", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YR31", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd22292", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22292", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "422746", "url": "https://www.ncbi.nlm.nih.gov/gene/422746", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR051877", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051877", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YJJ9", "url": "https://www.orthodb.org/?gene=A0A8V0YJJ9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YR25", "url": "https://www.orthodb.org/?gene=A0A8V0YR25", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YR31", "url": "https://www.orthodb.org/?gene=A0A8V0YR31", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR20544", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR20544", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR20544:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR20544:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "R-GGA-2565942", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2565942", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-380259", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-380259", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-380270", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-380270", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-380284", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-380284", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-380320", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-380320", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-5620912", "url": 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"https://www.uniprot.org/uniprotkb/A0A8V0YR31", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YR31-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YR31-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTTTAERKFVNLRKRLDQLGYRQPLGVESLPLVEKLFSDLVHTTESLRSAKLSAGKIEKECSNYDAIIEPYKTETAKLTRENNELHLEVLKLKEQSDHHIKDLKASLRRAENEAADLRFLNNQYVHKIKLLEKESKAKTEKIQQLQEKNLQAVVQTPGGRKRNIPFRRQRMQIDQPVPPSAVSAYPVPQPEDPYIADLLQVADNRIQELQSEVTQLQEKLEISENGKKNYSKQVELRDKEIERLMLALDGGRSHEVISLESRSKSNEKLIAQLNLQVEYLQQSNKELENRIQDLLDTKKNVTSEVVHLSNKNEELCQELNEIDHLAQQLERHKEIVLETADKEIGEAKKEIERKDSEIQDLEETITRLKSELSSCRRQNERLSEELFGKADDKENLELLLNQLEQEKQRLTEKTENFEIKERELVLEIERMRLEYGIALGDKSPSRLDAFVKTLEDDRDYYKRELEYLQKMIKRRPSPSRRSPEKSEDLRLITRERDELQSMLDRFEKHMIEIQSNVKLLTAERDRLNILYEQSQSELNRLRREAKHNLVSQSHVGEDGDASLADFRRLMAEKESLREKLKIQQEAANLEKSKMQHDISVLENNIQQFELERCELKSTISILKERIKSLENELKLKSSKLIQTSDDSSQLKAELCSLHLLNEQLQRTVEDLQHRFSLKKDELQSAQEEIVKLEEKIDRLNQKSTSQDEAVNVLRSTISVLDKEKDNLQETVDEKTEKIACLDDNLANKEKTITHLRLTLSELESSTDQLKDLLSSRDREISSLRRQLDASHTEIAETGRVKEIALKENRRLQDDLATMTRENQAVSSELEDAIREKEEMKTRVHNYITEVSRFESLIASKEKENQELLEKFRMLHTQAEDWEIKAHQAEGESSSIRLELLSVDTDRRHLRERVELLEKEIQEHMIAHQAYESQISSITKNMSKLEEDIKREHQDKSSVLADLTSVRELCVKLEASKDLLSRQLASKSMDYEKVLGELEDVKSEAELLKKQLSSERLTIQNLETLLATSRDKEFQNHLTSHEKDSEIQLLKDKLTLAEGKLSSHNREVSMLRSKVAQLQTDYDVLKRQLTTERFERERAIQEMRRHGLSTSSLRASPPLSSTLRSPSHSPDRAVARTADQAAAEKNVSFKE", "length": 1150, "header": "tr|A0A8V0YR31-1|A0A8V0YR31_CHICK Isoform 1 of Centrosomal protein 135 OS=Gallus gallus OX=9031 GN=CEP135 PE=1 SV=1 CANONICAL=A0A8V0YR31-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YJJ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YR31/entry#A0A8V0YJJ9-1", "sequence": { "sequence": "MTTTAERKFVNLRKRLDQLGYRQPLGVESLPLVEKLFSDLVHTTESLRSAKLSAGKIEKECSNYDAIIEPYKTETAKLTRENNELHLEVLKLKEQSDHHIKDLKASLRRAENEAADLRFLNNQYVHKIKLLEKESKAKTEKIQQLQEKNLQAVVQTPGGRKRNIPFRRQRMQIDQPVPPSAVSAYPVPQPEDPYIADLLQVADNRIQELQSEVTQLQEKLEISENGKKNYSKQVEYLQQSNKELENRIQDLLDTKKNVTSEVVHLSNKNEELCQELNEIDHLAQQLERHKEIVLETADKEIGEAKKEIERKDSEIQDLEETITRLKSELSSCRRQNERLSEELFGKADDKENLELLLNQLEQEKQRLTEKTENFEIKERELVLEIERMRLEYGIALGDKSPSRLDAFVKTLEDDRDYYKRELEYLQKMIKRRPSPSRRSPEKSEDLRLITRERDELQSMLDRFEKHMIEIQSNVKLLTAERDRLNILYEQSQSELNRLRREAKHNLVSQSHVGEDGDASLADFRRLMAEKESLREKLKIQQEAANLEKSKMQHDISVLENNIQQFELERCELKSTISILKERIKSLENELKLKSSKLIQTSDDSSQLKAELCSLHLLNEQLQRTVEDLQHRFSLKKDELQSAQEEIVKLEEKIDRLNQKSTSQDEAVNVLRSTISVLDKEKDNLQETVDEKTEKIACLDDNLANKEKTITHLRLTLSELESSTDQLKDLLSSRDREISSLRRQLDASHTEIAETGRVKEIALKENRRLQDDLATMTRENQAVSSELEDAIREKEEMKTRVHNYITEVSRFESLIASKEKENQELLEKFRMLHTQAEDWEIKAHQAEGESSSIRLELLSVDTDRRHLRERVELLEKEIQEHMIAHQAYESQISSITKNMSKLEEDIKREHQDKSSVLADLTSVRELCVKLEASKDLLSRQLASKSMDYEKVLGELEDVKSEAELLKKQLSSERLTIQNLETLLATSRDKEFQNHLTSHEKDSEIQLLKDKLTLAEGKLSSHNREVSMLRSKVAQLQTDYDVLKRQLTTERFERERAIQEMRRHGLSTSSLRASPPLSSTLRSPSHSPDRAVARTADQAAAEKNVSFKE", "length": 1107, "header": "tr|A0A8V0YJJ9-1|A0A8V0YR31_CHICK Computationally mapped isoform of Centrosomal protein 135 OS=Gallus gallus OX=9031 GN=CEP135 PE=1 SV=1 CANONICAL=A0A8V0YR31-1" }, "locus": { "chromosome": "4", "start_pos": 64473377, "end_pos": 64444551, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010036306.1", "url": "https://www.ensembl.org/id/ENSGALT00010036306.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021109.1", "url": "https://www.ensembl.org/id/ENSGALP00010021109.1" } ] } }, { "isoform_ac": "A0A8V0YR25-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YR31/entry#A0A8V0YR25-1", "sequence": { "sequence": "MTTTAERKFVNLRKRLDQLGYRQPLGVESLPLVEKLFSDLVHTTESLRSAKLSAGKIEKECSNYDAIIEPYKTETAKLTRENNELHLEVLKLKEQSDHHIKDLKASLRRAENEAADLRFLNNQYVHKIKLLEKESKAKTEKIQQLQEKNLQAVVQTPGGRKRNIPFRRQRMQIDQPVPPSAVSAYPVPQPEDPYIADLLQVADNRIQELQSEVTQLQEKLEISENGKKNYSKQVELRDKEIERLMLALDGGRSHEVISLESRSKSNEKLIAQLNLQVEYLQQSNKELENRIQDLLDTKKNVTSEVVHLSNKNEELCQELNEIDHLAQQLERHKEIVLETADKEIGEAKKEIERKDSEIQDLEETITRLKSELSSCRRQNERLSEELFGKADDKENLELLLNQLEQEKQRLTEKTENFEIKERELVLEIERMRLEYGIALGDKSPSRLDAFVKTLEDDRDYYKRELEYLQKMIKRRPSPSRRSPEKSEDLRLITRERDELQSMLDRFEKHMIEIQSNVKLLTAERDRLNILYEQSQSELNRLRREAKHNLVSQSHVGEDGDASLADFRRLMAEKESLREKLKIQQEAANLEKSKMQHDISVLENNIQQFELERCELKSTISILKERIKSLENELKLKSSKLIQTSDDSSQLKAELCSLHLLNEQLQRTVEDLQHRFSLKKDELQSAQEEIVKLEEKIDRLNQKSTSQDEAVNVLRSTISVLDKEKDNLQETVDEKTEKIACLDDNLANKEKTITHLRLTLSELESSTDQLKDLLSSRDREISSLRRQLDASHTEIAETGRVKEIALKENRRLQDDLATMTRENQAVSSELEDAIREKEEMKTRVHNYITEVSRFESLIASKEKENQELLEKFRMLHTQAEDWEIKAHQAEGESSSIRLELLSVDTDRRHLRERVELLEKEIQEHMIAHQAYESQISSITKNMSKLEEDIKREHQDKSSVLADLTSVRELCVKLEASKDLLSRQLASKSMDYEKVLGELEDVKSEAELLKKQLSSERLTIQNLETLLATSRDKEFQNHLTSHEKDSEIQLLKDKLTLAEGKLAITKILSSEIKGSGPSPLLSTGEAPPGAQCPVLGSPVQE", "length": 1099, "header": "tr|A0A8V0YR25-1|A0A8V0YR25_CHICK Computationally mapped isoform of Centrosomal protein 135 OS=Gallus gallus OX=9031 GN=CEP135 PE=1 SV=1 CANONICAL=A0A8V0YR31-1" }, "locus": { "chromosome": "4", "start_pos": 64473377, "end_pos": 64450112, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010036305.1", "url": "https://www.ensembl.org/id/ENSGALT00010036305.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021108.1", "url": "https://www.ensembl.org/id/ENSGALP00010021108.1" } ] } }, { "isoform_ac": "A0A8V0YR31-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YR31/entry#A0A8V0YR31-1", "sequence": { "sequence": "MTTTAERKFVNLRKRLDQLGYRQPLGVESLPLVEKLFSDLVHTTESLRSAKLSAGKIEKECSNYDAIIEPYKTETAKLTRENNELHLEVLKLKEQSDHHIKDLKASLRRAENEAADLRFLNNQYVHKIKLLEKESKAKTEKIQQLQEKNLQAVVQTPGGRKRNIPFRRQRMQIDQPVPPSAVSAYPVPQPEDPYIADLLQVADNRIQELQSEVTQLQEKLEISENGKKNYSKQVELRDKEIERLMLALDGGRSHEVISLESRSKSNEKLIAQLNLQVEYLQQSNKELENRIQDLLDTKKNVTSEVVHLSNKNEELCQELNEIDHLAQQLERHKEIVLETADKEIGEAKKEIERKDSEIQDLEETITRLKSELSSCRRQNERLSEELFGKADDKENLELLLNQLEQEKQRLTEKTENFEIKERELVLEIERMRLEYGIALGDKSPSRLDAFVKTLEDDRDYYKRELEYLQKMIKRRPSPSRRSPEKSEDLRLITRERDELQSMLDRFEKHMIEIQSNVKLLTAERDRLNILYEQSQSELNRLRREAKHNLVSQSHVGEDGDASLADFRRLMAEKESLREKLKIQQEAANLEKSKMQHDISVLENNIQQFELERCELKSTISILKERIKSLENELKLKSSKLIQTSDDSSQLKAELCSLHLLNEQLQRTVEDLQHRFSLKKDELQSAQEEIVKLEEKIDRLNQKSTSQDEAVNVLRSTISVLDKEKDNLQETVDEKTEKIACLDDNLANKEKTITHLRLTLSELESSTDQLKDLLSSRDREISSLRRQLDASHTEIAETGRVKEIALKENRRLQDDLATMTRENQAVSSELEDAIREKEEMKTRVHNYITEVSRFESLIASKEKENQELLEKFRMLHTQAEDWEIKAHQAEGESSSIRLELLSVDTDRRHLRERVELLEKEIQEHMIAHQAYESQISSITKNMSKLEEDIKREHQDKSSVLADLTSVRELCVKLEASKDLLSRQLASKSMDYEKVLGELEDVKSEAELLKKQLSSERLTIQNLETLLATSRDKEFQNHLTSHEKDSEIQLLKDKLTLAEGKLSSHNREVSMLRSKVAQLQTDYDVLKRQLTTERFERERAIQEMRRHGLSTSSLRASPPLSSTLRSPSHSPDRAVARTADQAAAEKNVSFKE", "length": 1150, "header": "tr|A0A8V0YR31-1|A0A8V0YR31_CHICK Isoform 1 of Centrosomal protein 135 OS=Gallus gallus OX=9031 GN=CEP135 PE=1 SV=1 CANONICAL=A0A8V0YR31-1" }, "locus": { "chromosome": "4", "start_pos": 64473377, "end_pos": 64444551, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010036310.1", "url": "https://www.ensembl.org/id/ENSGALT00010036310.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021113.1", "url": "https://www.ensembl.org/id/ENSGALP00010021113.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-2565942", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2565942", "resource": "Reactome", "description": "Regulation of PLK1 Activity at G2/M Transition" }, { "id": "R-GGA-380259", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-380259", "resource": "Reactome", "description": "Loss of Nlp from mitotic 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], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "centriole", "id": "GO:0005814", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005814", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YR31", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YR31" } ], "pmid": "" }, { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YR31", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YR31" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "positive regulation of establishment of protein localization", "id": "GO:1904951", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904951", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YR31", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YR31" } ], "pmid": "" }, { "name": "positive regulation of non-motile cilium assembly", "id": "GO:1902857", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902857", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YR31", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YR31" } ], "pmid": "" }, { "name": "centriole-centriole cohesion", "id": "GO:0010457", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010457", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YR31", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YR31" } ], "pmid": "" }, { "name": "centriole replication", "id": "GO:0007099", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007099", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YR31", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YR31" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "microtubule binding", "id": "GO:0008017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008017", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YR31", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YR31" } ], "pmid": 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This record is derived from a genomic sequence (NC_059536) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. 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"InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:100857774", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100857774", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YJS5", "url": "https://www.orthodb.org/?gene=A0A8V0YJS5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YR67", "url": "https://www.orthodb.org/?gene=A0A8V0YR67", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YRA1", "url": "https://www.orthodb.org/?gene=A0A8V0YRA1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YRA6", "url": "https://www.orthodb.org/?gene=A0A8V0YRA6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YXY2", "url": "https://www.orthodb.org/?gene=A0A8V0YXY2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1N8Y9", "url": "https://www.orthodb.org/?gene=F1N8Y9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31075", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31075", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31075:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31075:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF24555", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24555", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YJS5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJS5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJS5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJS5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YR67", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YR67", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YR67-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YR67-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YRA1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRA1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YRA1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRA1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YRA6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRA6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YRA6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRA6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YXY2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXY2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YXY2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXY2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N8Y9", "url": "https://www.uniprot.org/uniprotkb/F1N8Y9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N8Y9-1", "url": "https://www.uniprot.org/uniprotkb/F1N8Y9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MWGGLQPQLGAGPRGYRAGSDYSSVGWLPGTESLWQSATIASSSQSNPVRRHSIASDSGDTGIGTSCSDSVEEGENVWRFSLPGGKQWISSDHSTSSGTSSFKPSRSLVSIPTAHVMPSNASPSLSKHREAFKSDGSKWSTSFVRSGGGRNPDALDNSLDMKAARPVRKWSSLSKLSSPNTFSQDGSSHSVDSRAGTDKAVSPPLRTNGPNCLHDSMELLKIEDKEIGKKRSSLLDCKYKFETCNKDDFVLDSSSRRHALDLNYSALPESKPAAASCEAFGQRYATLGQQAVSGAPIQPAVRTQMWLKEQLRANPLDCRTAEEPYGVASWHVQQLEDFRPGGEEPVQVPTGTSRQSYPATTYQDFSNWESLMKIKEGLLRQKEIVIDRQKQQINNLHQKIRENELRVQHARLSHLVNCEEPYMTNLQQPQYESASLQPHVSERSASHLEELERKIAVAENKELQLSEFLKQISNKSMEEKKKMEEKLKTRDRYINSLKKKCQKESEQNKEKQRRIETLEKYLADLPTLDDIEGQTKQLQILVEKNKQLQESMTELEKKLGEARSQCREREMQLVCQKKKEKELVTTVQSLQQKVEKCLEDGIRLPMLDTKQLQSENECLKEKNEKASKVIDNQQKQIEGLILDMQSMQEKLLQEKRTVLKMTNELEEKERNIEQLNKTLSENQRLTEENASLKEQIRQVEQSRQPVSEKMPVADQLFKEMSHCLFDLKALCSILTQRAQGKEPNLSLLLGIRSLNCSAEENENYHSTETLSKKLSDVCQLRKDIDELRTIMSDRYAQDMGDNCITQ", "length": 806, "header": "tr|A0A8V0YR67-1|A0A8V0YR67_CHICK Isoform 1 of Centrosomal protein 85 like OS=Gallus gallus OX=9031 GN=CEP85L PE=4 SV=1 CANONICAL=A0A8V0YR67-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YJS5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YR67/entry#A0A8V0YJS5-1", "sequence": { "sequence": "MSAWGSDYSSVGWLPGTESLWQSATIASSSQSNPVRRHSIASDSGDTGIGTSCSDSVEDHSTSSGTSSFKPSRSLVSIPTAHVMPSNASPSLSKHREAFKSDGSKWSTSFVRSGGGRNPDALDNSLDMKAARPVRKWSSLSKLSSPNTFSQDGSSHSVDSRAGTDKAVSPPLRTNGPNCLHDSMELLKIEDKEIGKKRSSLLDCKYKFETCNKDDFVLDSSSRRHALDLNYSALPESKPAAASCEAFGQRYATLGQQAVSGAPIQPAVRTQMWLKEQLRANPLDCRTAEEPYGVASWHVQQLEDFRPGGEEPVQVPTGTSRQSYPATTYQDFSNWESLMKIKEGLLRQKEIVIDRQKQQINNLHQKIRENELRVQHARLSHLVNCEEPYMTNLQQPQYESASLQPHVSERSASHLEELERKIAVAENKELQLSEFLKQISNKSMEEKKKMEEKLKTRDRYINSLKKKCQKESEQNKEKQRRIETLEKYLADLPTLDDIEGQTKQLQILVEKNKQLQESMTELEKKLGEARSQCREREMQLVCQKKKEKELVTTVQSLQQKVEKCLEDGIRLPMLDTKQLQSENECLKEKNEKASKVIDNQQKQIEGLILDMQSMQEKLLQEKRTVLKMTNELEEKERNIEQLNKTLSENQRLTEENASLKEQIRQVEQSRQPVSEKMPVADQLFKEMSHCLFDLKALCSILTQRAQGKEPNLSLLLGIRSLNCSAEENENYHSTETLSKKLSDVCQLRKDIDELRTIMSDRYAQDMGDNCITQ", "length": 773, "header": "tr|A0A8V0YJS5-1|A0A8V0YR67_CHICK Computationally mapped isoform of Centrosomal protein 85 like OS=Gallus gallus OX=9031 GN=CEP85L PE=4 SV=1 CANONICAL=A0A8V0YR67-1" }, "locus": { "chromosome": "3", "start_pos": 62645469, "end_pos": 62534735, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010036414.1", "url": "https://www.ensembl.org/id/ENSGALT00010036414.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021187.1", "url": "https://www.ensembl.org/id/ENSGALP00010021187.1" } ] } }, { "isoform_ac": "A0A8V0YR67-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YR67/entry#A0A8V0YR67-1", "sequence": { "sequence": "MWGGLQPQLGAGPRGYRAGSDYSSVGWLPGTESLWQSATIASSSQSNPVRRHSIASDSGDTGIGTSCSDSVEEGENVWRFSLPGGKQWISSDHSTSSGTSSFKPSRSLVSIPTAHVMPSNASPSLSKHREAFKSDGSKWSTSFVRSGGGRNPDALDNSLDMKAARPVRKWSSLSKLSSPNTFSQDGSSHSVDSRAGTDKAVSPPLRTNGPNCLHDSMELLKIEDKEIGKKRSSLLDCKYKFETCNKDDFVLDSSSRRHALDLNYSALPESKPAAASCEAFGQRYATLGQQAVSGAPIQPAVRTQMWLKEQLRANPLDCRTAEEPYGVASWHVQQLEDFRPGGEEPVQVPTGTSRQSYPATTYQDFSNWESLMKIKEGLLRQKEIVIDRQKQQINNLHQKIRENELRVQHARLSHLVNCEEPYMTNLQQPQYESASLQPHVSERSASHLEELERKIAVAENKELQLSEFLKQISNKSMEEKKKMEEKLKTRDRYINSLKKKCQKESEQNKEKQRRIETLEKYLADLPTLDDIEGQTKQLQILVEKNKQLQESMTELEKKLGEARSQCREREMQLVCQKKKEKELVTTVQSLQQKVEKCLEDGIRLPMLDTKQLQSENECLKEKNEKASKVIDNQQKQIEGLILDMQSMQEKLLQEKRTVLKMTNELEEKERNIEQLNKTLSENQRLTEENASLKEQIRQVEQSRQPVSEKMPVADQLFKEMSHCLFDLKALCSILTQRAQGKEPNLSLLLGIRSLNCSAEENENYHSTETLSKKLSDVCQLRKDIDELRTIMSDRYAQDMGDNCITQ", "length": 806, "header": "tr|A0A8V0YR67-1|A0A8V0YR67_CHICK Isoform 1 of Centrosomal protein 85 like OS=Gallus gallus OX=9031 GN=CEP85L PE=4 SV=1 CANONICAL=A0A8V0YR67-1" }, "locus": { "chromosome": "3", "start_pos": 62645469, "end_pos": 62533921, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010036417.1", "url": "https://www.ensembl.org/id/ENSGALT00010036417.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021189.1", "url": "https://www.ensembl.org/id/ENSGALP00010021189.1" } ] } }, { "isoform_ac": "A0A8V0YRA1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YR67/entry#A0A8V0YRA1-1", "sequence": { "sequence": "MWSANMTTSSDYSSVGWLPGTESLWQSATIASSSQSNPVRRHSIASDSGDTGIGTSCSDSVEDHSTSSGTSSFKPSRSLVSIPTAHVMPSNASPSLSKHREAFKSDGSKWSTSFVRSGGGRNPDALDNSLDMKAARPVRKWSSLSKLSSPNTFSQDGSSHSVDSRAGTDKAVSPPLRTNGPNCLHDSMELLKIEDKEIGKKRSSLLDCKYKFETCNKDDFVLDSSSRRHALDLNYSALPESKPAAASCEAFGQRYATLGQQAVSGAPIQPAVRTQMWLKEQLRANPLDCRTAEEPYGVASWHVQQLEDFRPGGEEPVQVPTGTSRQSYPATTYQDFSNWESLMKIKEGLLRQKEIVIDRQKQQINNLHQKIRENELRVQHARLSHLVNCEEPYMTNLQQPQYESASLQPHVSERSASHLEELERKIAVAENKELQLSEFLKQISNKSMEEKKKMEEKLKTRDRYINSLKKKCQKESEQNKEKQRRIETLEKYLADLPTLDDIEGQTKQLQILVEKNKQLQESMTELEKKLGEARSQCREREMQLVCQKKKEKELVTTVQSLQQKVEKCLEDGIRLPMLDTKQLQSENECLKEKNEKASKVIDNQQKQIEGLILDMQSMQEKLLQEKRTVLKMTNELEEKERNIEQLNKTLSENQRLTEENASLKEQIRQVEQSRQPVSEKMPVADQLFKEMSHCLFDLKALCSILTQRAQGKEPNLSLLLGIRSLNCSAEENENYHSTETLSKKLSDVCQLRKDIDELRTIMSDRYAQDMGDNCITQ", "length": 777, "header": "tr|A0A8V0YRA1-1|A0A8V0YRA1_CHICK Computationally mapped isoform of Centrosomal protein 85 like OS=Gallus gallus OX=9031 GN=CEP85L PE=4 SV=1 CANONICAL=A0A8V0YR67-1" }, "locus": { "chromosome": "3", "start_pos": 62645469, "end_pos": 62547419, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010036412.1", "url": "https://www.ensembl.org/id/ENSGALT00010036412.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021186.1", "url": "https://www.ensembl.org/id/ENSGALP00010021186.1" } ] } }, { "isoform_ac": "A0A8V0YRA6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YR67/entry#A0A8V0YRA6-1", "sequence": { "sequence": "MWGGLQPQLGAGPRGYRADHSTSSGTSSFKPSRSLVSIPTAHVMPSNASPSLSKHREAFKSDGSKWSTSFVRSGGGRNPDALDNSLDMKAARPVRKWSSLSKLSSPNTFSQDGSSHSVDSRAGTDKAVSPPLRTNGPNCLHDSMELLKIEDKEIGKKRSSLLDCKYKFETCNKDDFVLDSSSRRHALDLNYSALPESKPAAASCEAFGQRYATLGQQAVSGAPIQPAVRTQMWLKEQLRANPLDCRTAEEPYGVASWHVQQLEDFRPGGEEPVQVPTGTSRQSYPATTYQDFSNWESLMKIKEGLLRQKEIVIDRQKQQINNLHQKIRENELRVQHARLSHLVNCEEPYMTNLQQPQYESASLQPHVSERSASHLEELERKIAVAENKELQLSEFLKQISNKSMEEKKKMEEKLKTRDRYINSLKKKCQKESEQNKEKQRRIETLEKYLADLPTLDDIEGQTKQLQILVEKNKQLQESMTELEKKLGEARSQCREREMQLVCQKKKEKELVTTVQSLQQKVEKCLEDGIRLPMLDTKQLQSENECLKEKNEKASKVIDNQQKQIEGLILDMQSMQEKLLQEKRTVLKMTNELEEKERNIEQLNKTLSENQRLTEENASLKEQIRQVEQSRQPVSEKMPVADQLFKEMSHCLFDLKALCSILTQRAQGKEPNLSLLLGIRSLNCSAEENENYHSTETLSKKLSDVCQLRKDIDELRTIMSDRYAQDMGDNCITQ", "length": 733, "header": "tr|A0A8V0YRA6-1|A0A8V0YRA6_CHICK Computationally mapped isoform of Centrosomal protein 85 like OS=Gallus gallus OX=9031 GN=CEP85L PE=4 SV=1 CANONICAL=A0A8V0YR67-1" }, "locus": { "chromosome": "3", "start_pos": 62645469, "end_pos": 62533921, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010036421.1", "url": "https://www.ensembl.org/id/ENSGALT00010036421.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021191.1", "url": "https://www.ensembl.org/id/ENSGALP00010021191.1" } ] } }, { "isoform_ac": "A0A8V0YXY2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YR67/entry#A0A8V0YXY2-1", "sequence": { "sequence": "MCPMTGVLVGSDYSSVGWLPGTESLWQSATIASSSQSNPVRRHSIASDSGDTGIGTSCSDSVEDHSTSSGTSSFKPSRSLVSIPTAHVMPSNASPSLSKHREAFKSDGSKWSTSFVRSGGGRNPDALDNSLDMKAARPVRKWSSLSKLSSPNTFSQDGSSHSVDSRAGTDKAVSPPLRTNGPNCLHDSMELLKIEDKEIGKKRSSLLDCKYKFETCNKDDFVLDSSSRRHALDLNYSALPESKPAAASCEAFGQRYATLGQQAVSGAPIQPAVRTQMWLKEQLRANPLDCRTAEEPYGVASWHVQQLEDFRPGGEEPVQVPTGTSRQSYPATTYQDFSNWESLMKIKEGLLRQKEIVIDRQKQQINNLHQKIRENELRVQHARLSHLVNCEEPYMTNLQQPQYESASLQPHVSERSASHLEELERKIAVAENKELQLSEFLKQISNKSMEEKKKMEEKLKTRDRYINSLKKKCQKESEQNKEKQRRIETLEKYLADLPTLDDIEGQTKQLQILVEKNKQLQESMTELEKKLGEARSQCREREMQLVCQKKKEKELVTTVQSLQQKVEKCLEDGIRLPMLDTKQLQSENECLKEKNEKASKVIDNQQKQIEGLILDMQSMQEKLLQEKRTVLKMTNELEEKERNIEQLNKTLSENQRLTEENASLKEQIRQVEQSRQPVSEKMPVADQLFKEMSHCLFDLKALCSILTQRAQGKEPNLSLLLGIRSLNCSAEENENYHSTETLSKKLSDVCQLRKDIDELRTIMSDRYAQDMGDNCITQ", "length": 778, "header": "tr|A0A8V0YXY2-1|A0A8V0YXY2_CHICK Computationally mapped isoform of Centrosomal protein 85 like OS=Gallus gallus OX=9031 GN=CEP85L PE=4 SV=1 CANONICAL=A0A8V0YR67-1" }, "locus": { "chromosome": "3", "start_pos": 62645469, "end_pos": 62510876, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010036423.1", "url": "https://www.ensembl.org/id/ENSGALT00010036423.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021193.1", "url": "https://www.ensembl.org/id/ENSGALP00010021193.1" } ] } }, { "isoform_ac": "F1N8Y9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YR67/entry#F1N8Y9-1", "sequence": { "sequence": "MKTASSDYSSVGWLPGTESLWQSATIASSSQSNPVRRHSIASDSGDTGIGTSCSDSVEDHSTSSGTSSFKPSRSLVSIPTAHVMPSNASPSLSKHREAFKSDGSKWSTSFVRSGGGRNPDALDNSLDMKAARPVRKWSSLSKLSSPNTFSQDGSSHSVDSRAGTDKAVSPPLRTNGPNCLHDSMELLKIEDKEIGKKRSSLLDCKYKFETCNKDDFVLDSSSRRHALDLNYSALPESKPAAASCEAFGQRYATLGQQAVSGAPIQPAVRTQMWLKEQLRANPLDCRTAEEPYGVASWHVQQLEDFRPGGEEPVQVPTGTSRQSYPATTYQDFSNWESLMKIKEGLLRQKEIVIDRQKQQINNLHQKIRENELRVQHARLSHLVNCEEPYMTNLQQPQYESASLQPHVSERSASHLEELERKIAVAENKELQLSEFLKQISNKSMEEKKKMEEKLKTRDRYINSLKKKCQKESEQNKEKQRRIETLEKYLADLPTLDDIEGQTKQLQILVEKNKQLQESMTELEKKLGEARSQCREREMQLVCQKKKEKELVTTVQSLQQKVEKCLEDGIRLPMLDTKQLQSENECLKEKNEKASKVIDNQQKQIEGLILDMQSMQEKLLQEKRTVLKMTNELEEKERNIEQLNKTLSENQRLTEENASLKEQIRQVEQSRQPVSEKMPVADQLFKEMSHCLFDLKALCSILTQRAQGKEPNLSLLLGIRSLNCSAEENENYHSTETLSKKLSDVCQLRKDIDELRTIMSDRYAQDMGDNCITQ", "length": 773, "header": "tr|F1N8Y9-1|F1N8Y9_CHICK Computationally mapped isoform of Centrosomal protein 85 like OS=Gallus gallus OX=9031 GN=CEP85L PE=4 SV=3 CANONICAL=A0A8V0YR67-1" }, "locus": { "chromosome": "3", "start_pos": 62645469, "end_pos": 62503497, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010036424.1", "url": "https://www.ensembl.org/id/ENSGALT00010036424.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021194.1", "url": "https://www.ensembl.org/id/ENSGALP00010021194.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:100857774", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100857774", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YR67", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YR67" } ], "pmid": "" }, { "name": "pericentriolar material", "id": "GO:0000242", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000242", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YR67", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YR67" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "neuron migration", "id": "GO:0001764", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001764", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YR67", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YR67" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 120, "end_pos": 122, "annotation": "n_glycosylation_sequon" }, { "start_pos": 263, "end_pos": 265, "annotation": "n_glycosylation_sequon" }, { "start_pos": 474, "end_pos": 476, "annotation": "n_glycosylation_sequon" }, { "start_pos": 676, "end_pos": 678, "annotation": "n_glycosylation_sequon" }, { "start_pos": 689, "end_pos": 691, "annotation": "n_glycosylation_sequon" }, { "start_pos": 744, "end_pos": 746, "annotation": "n_glycosylation_sequon" }, { "start_pos": 755, "end_pos": 757, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YR67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YR67" }, { "id": "PF24555", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24555" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Centrosomal protein of 85 kDa-like CC4 coiled-coil", "eco_id": "ECO_0000259", "start_pos": 613, "end_pos": 693, "start_aa": "Gln", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 120, "end_pos": 122 }, { "start_pos": 263, "end_pos": 265 }, { "start_pos": 474, "end_pos": 476 }, { "start_pos": 676, "end_pos": 678 }, { "start_pos": 689, "end_pos": 691 }, { "start_pos": 744, "end_pos": 746 }, { "start_pos": 755, "end_pos": 757 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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{ "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YQ70-1", "uniprot_ac": "A0A8V0YQ70", "uniprot_id": "A0A8V0YQ70_CHICK", "mass": { "chemical_mass": 63768.0, "monoisotopic_mass": 63768.0 }, "refseq": {}, "gene_names": [ { "name": "CHAF1B", "type": "recommended", "evidence": [ { "id": "A0A8V0YQ70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ70" } ] } ], "protein_names": [ { "name": "Chromatin assembly factor 1 subunit B", "type": "recommended", "evidence": [ { "id": "A0A8V0YQ70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ70/entry#names_and_taxonomy" } ] }, { "name": "Chromatin assembly factor I p60 subunit", "type": "synonym", "evidence": [ { "id": "A0A8V0YQ70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ70/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Acts as a component of the histone chaperone complex chromatin assembly factor 1 (CAF-1), which assembles histone octamers onto DNA during replication and repair. 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"database": "Ensembl Transcript", "id": "ENSGALT00010031380.1", "url": "https://www.ensembl.org/id/ENSGALT00010031380.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018308.1", "url": "https://www.ensembl.org/id/ENSGALP00010018308.1" } ] } }, { "isoform_ac": "A0A8V0YQ70-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ70/entry#A0A8V0YQ70-1", "sequence": { "sequence": "MIFLKLPSSDMKVITCEIAWHNKEPVYSLDFQHGTDGKINRLASAGVDTAVRVWKVEKGPDGKAIVEFLSNLARHTKAVNVVRFSPSGEVLASGGDDAVILLWKLNDSKELEPLAFQDEDEAQLNKENWTVVKTLRGHLEDVYDICWTSDGNYMASASVDNTAIMWDVVKGQKVSILNEHKSYVQGITWDPLGQYIATLSCDRVLRVYNTQTKRVAFNVTKMPSESGAEGEARSYRMFHDDSMKSFFRRLSFTPDGSLLLTPAGCVESGENVTNTTYVFSRNNLKRPMGHLPCPGKATLAVRCCPVYFELRQALNKGEVSQKSSPALLNLPYRLVFAVASEDSVLFYDTEQSFPFGYVSNIHYHTLSDISWSSDGAFLAISSTDGYCSFVTFEKDELGIPLKEKPQIHVRTSVVTEKKVKKSQPNKVISPGSRLTEGTSLSTPTLQPKTPVAAAKDLPSTPVGIKNVPVSSSEERKISQPASQSTKVNQPRRITLNTLQAWSKTPRRVNLIPLKPDTPASVYTDTVPVPPSSEQEHERPLPSDDSLQNPPASKRPRTEEMPLSVSAEDQIGCKPNK", "length": 576, "header": "tr|A0A8V0YQ70-1|A0A8V0YQ70_CHICK Isoform 1 of Chromatin assembly factor 1 subunit B OS=Gallus gallus OX=9031 GN=CHAF1B PE=3 SV=1 CANONICAL=A0A8V0YQ70-1" }, "locus": { "chromosome": "1", "start_pos": 106771134, "end_pos": 106754760, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031364.1", "url": "https://www.ensembl.org/id/ENSGALT00010031364.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018296.1", "url": "https://www.ensembl.org/id/ENSGALP00010018296.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQ70", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ70" } ], "pmid": "" }, { "name": "nucleoplasm", 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replication", "id": "GO:0006260", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006260", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQ70", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ70" } ], "pmid": "" }, { "name": "DNA replication-dependent chromatin assembly", "id": "GO:0006335", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006335", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQ70", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ70" } ], "pmid": "" }, { "name": "nucleosome assembly", "id": "GO:0006334", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006334", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQ70", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ70" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 106, "end_pos": 108, "annotation": "n_glycosylation_sequon" }, { "start_pos": 128, "end_pos": 130, "annotation": "n_glycosylation_sequon" }, { "start_pos": 218, "end_pos": 220, "annotation": 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"chemical_mass": 51193.0, "monoisotopic_mass": 51193.0 }, "refseq": {}, "gene_names": [ { "name": "IL1R2", "type": "recommended", "evidence": [ { "id": "A0A8V0YN49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN49" } ] } ], "protein_names": [ { "name": "Interleukin 1 receptor type 2", "type": "synonym", "evidence": [ { "id": "A0A8V0YN49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN49/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YN49", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN49" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "IL1R2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN49", "locus": { "chromosome": "1", "start_pos": 133871411, "end_pos": 133853445, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013619", "url": "https://www.ensembl.org/id/ENSGALG00010013619" } ] } } ], "crossref": [ { "id": "A0A8V0YN49", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YN49", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd05897", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05897", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "418715", "url": "https://www.ncbi.nlm.nih.gov/gene/418715", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004074", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004074", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004077", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004077", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015621", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015621", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041416", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041416", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "LLWWTAN", "url": "https://omabrowser.org/oma/group/LLWWTAN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YKQ7", "url": "https://www.orthodb.org/?gene=A0A8V0YKQ7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YN49", "url": "https://www.orthodb.org/?gene=A0A8V0YN49", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YT44", "url": "https://www.orthodb.org/?gene=A0A8V0YT44", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11890", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11890", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11890:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11890:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF18452", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18452", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-9020702", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9020702", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YKQ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKQ7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YKQ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKQ7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YN49", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN49", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YN49-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN49-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YT44", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YT44", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YT44-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YT44-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVERMQNHRFQDTFPRSSSHFLWERMHGFFFALVTCTMCASAFKLQQGKSTGKGMALVVLFSISLSFSLMCLANSNDKMSLIHIENCPDHTMFFQYYYELHGEPVVLKCPSPRYKHVDFSALTHNITWYKNDSKTMILGRDEDPRIWAKGDALWFLPARQEDSGVYICTRRNNSYCAEVSIQLTVVQKAAARDIAYPQILFTFTSGKIVCPNLWEFTINRTNMELQWYKDALLLEDDSEKFVFLKESSSLFFTSVLPTDSGYYTCKMAFPYEGVTYEITRTIKLQTVEQEKRITPIIVYPTQKTTTAALGSKMTLPCKVFAGPNSKVYTDVEWLANDTTIDMVYKQNRVMEGERQETTENGENFIEVPLIFKSVEEVDFYTDFKCLAQNRYGSQVLPTRVKQEAVGLPWYIATIPVALACVILAGICIQKRWKQRTDKGYTIAKV", "length": 445, "header": "tr|A0A8V0YN49-1|A0A8V0YN49_CHICK Isoform 1 of Interleukin 1 receptor type 2 OS=Gallus gallus OX=9031 GN=IL1R2 PE=3 SV=1 CANONICAL=A0A8V0YN49-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YKQ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN49/entry#A0A8V0YKQ7-1", "sequence": { "sequence": "MGRRPLHFPEGNHKTRFQDTFPRSSSHFLWERMHGFFFALVTCTMCASAFKLQQGKSTENCPDHTMFFQYYYELHGEPVVLKCPSPRYKHVDFSALTHNITWYKNDSKTMILGRDEDPRIWAKGDALWFLPARQEDSGVYICTRRNNSYCAEVSIQLTVVQKAAARDIAYPQILFTFTSGKIVCPNLWEFTINRTNMELQWYKDALLLEDDSEKFVFLKESSSLFFTSVLPTDSGYYTCKMAFPYEGVTYEITRTIKLQTVEQEKRITPIIVYPTQKTTTAALGSKMTLPCKVFAGPNSKVYTDVEWLANDTTIDMVYKQNRVMEGERQETTENGENFIEVPLIFKSVEEVDFYTDFKCLAQNRYGSQVLPTRVKQEAVGLPWYIATIPVALACVILAGICIQKRWKQRTDKGYTIAKV", "length": 419, "header": "tr|A0A8V0YKQ7-1|A0A8V0YN49_CHICK Computationally mapped isoform of Interleukin 1 receptor type 2 OS=Gallus gallus OX=9031 GN=IL1R2 PE=3 SV=1 CANONICAL=A0A8V0YN49-1" }, "locus": { "chromosome": "1", "start_pos": 133870007, "end_pos": 133854610, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032727.1", "url": "https://www.ensembl.org/id/ENSGALT00010032727.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019390.1", "url": "https://www.ensembl.org/id/ENSGALP00010019390.1" } ] } }, { "isoform_ac": "A0A8V0YN49-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN49/entry#A0A8V0YN49-1", "sequence": { "sequence": "MVERMQNHRFQDTFPRSSSHFLWERMHGFFFALVTCTMCASAFKLQQGKSTGKGMALVVLFSISLSFSLMCLANSNDKMSLIHIENCPDHTMFFQYYYELHGEPVVLKCPSPRYKHVDFSALTHNITWYKNDSKTMILGRDEDPRIWAKGDALWFLPARQEDSGVYICTRRNNSYCAEVSIQLTVVQKAAARDIAYPQILFTFTSGKIVCPNLWEFTINRTNMELQWYKDALLLEDDSEKFVFLKESSSLFFTSVLPTDSGYYTCKMAFPYEGVTYEITRTIKLQTVEQEKRITPIIVYPTQKTTTAALGSKMTLPCKVFAGPNSKVYTDVEWLANDTTIDMVYKQNRVMEGERQETTENGENFIEVPLIFKSVEEVDFYTDFKCLAQNRYGSQVLPTRVKQEAVGLPWYIATIPVALACVILAGICIQKRWKQRTDKGYTIAKV", "length": 445, "header": "tr|A0A8V0YN49-1|A0A8V0YN49_CHICK Isoform 1 of Interleukin 1 receptor type 2 OS=Gallus gallus OX=9031 GN=IL1R2 PE=3 SV=1 CANONICAL=A0A8V0YN49-1" }, "locus": { "chromosome": "1", "start_pos": 133870007, "end_pos": 133859322, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032709.1", "url": "https://www.ensembl.org/id/ENSGALT00010032709.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019379.1", "url": "https://www.ensembl.org/id/ENSGALP00010019379.1" } ] } }, { "isoform_ac": "A0A8V0YT44-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN49/entry#A0A8V0YT44-1", "sequence": { "sequence": "MVERMQNHRFQDTFPRSSSHFLWERMHGFFFALVTCTMCASAFKLQQGKSTENCPDHTMFFQYYYELHGEPVVLKCPSPRYKHVDFSALTHNITWYKNDSKTMILGRDEDPRIWAKGDALWFLPARQEDSGVYICTRRNNSYCAEVSIQLTVVQKAAARDIAYPQILFTFTSGKIVCPNLWEFTINRTNMELQWYKDALLLEDDSEKFVFLKESSSLFFTSVLPTDSGYYTCKMAFPYEGVTYEITRTIKLQTVEQEKRITPIIVYPTQKTTTAALGSKMTLPCKVFAGPNSKVYTDVEWLANDTTIDMVYKQNRVMEGERQETTENGENFIEVPLIFKSVEEVDFYTDFKCLAQNRYGSQVLPTRVKQEAVGLPWYIATIPVALACVILAGICIQKRWKQRTDKGYTIAKV", "length": 412, "header": "tr|A0A8V0YT44-1|A0A8V0YT44_CHICK Computationally mapped isoform of Interleukin 1 receptor type 2 OS=Gallus gallus OX=9031 GN=IL1R2 PE=3 SV=1 CANONICAL=A0A8V0YN49-1" }, "locus": { "chromosome": "1", "start_pos": 133870007, "end_pos": 133859322, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032716.1", "url": "https://www.ensembl.org/id/ENSGALT00010032716.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019382.1", "url": "https://www.ensembl.org/id/ENSGALP00010019382.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-9020702", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9020702", "resource": "Reactome", "description": "Interleukin-1 signaling" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2QGG3-1", "protein_name": "Interleukin-1 receptor type 2", "gene_name": "Il1r2", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MFILCVLVTGVSALTTSSVVPTERASGSPVTSENHTVLEDNCLFRGRDFKSEFRLEGEPVTLRCPLKWPHSDASASFYPFLTWHKMNSSQLIPGDEPRLWVKDATLWVLPAVQKDSGTYICTFRNASHCEEMSIELKVFKNTEASLPLISYSQISSVSTTGLLVCPDLKEFIPNKADGKVQWYKGSVLLDRNSKKFLRVGDGTHILIANTSMEDAGYYRCIATFIHKGKEYNITRNIKLRVEEASTETIPVIISPLETIPASLGSRLIVPCKVFLGTDASSNTIVWWMANSTFISVAYPRGRVTEGLYHEYSENHENYMEVSLIFDPVTREDLNTDFKCVAKNSRSVQSLHTTVKEVSSTFSWGIALAPLSLVFLVVGGIWMHRRCKQTYGLTKLRTDNKDFPSSPDQIKEMK", "length": 413 }, "evidence": [ { "id": "A0A8V0YN49", "url": "https://omabrowser.org/oma/group/A0A8V0YN49/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P27930-1", "protein_name": "Interleukin-1 receptor type 2", "gene_name": "IL1R2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLRLYVLVMGVSAFTLQPAAHTGAARSCRFRGRHYKREFRLEGEPVALRCPQVPYWLWASVSPRINLTWHKNDSARTVPGEEETRMWAQDGALWLLPALQEDSGTYVCTTRNASYCDKMSIELRVFENTDAFLPFISYPQILTLSTSGVLVCPDLSEFTRDKTDVKIQWYKDSLLLDKDNEKFLSVRGTTHLLVHDVALEDAGYYRCVLTFAHEGQQYNITRSIELRIKKKKEETIPVIISPLKTISASLGSRLTIPCKVFLGTGTPLTTMLWWTANDTHIESAYPGGRVTEGPRQEYSENNENYIEVPLIFDPVTREDLHMDFKCVVHNTLSFQTLRTTVKEASSTFSWGIVLAPLSLAFLVLGGIWMHRRCKHRTGKADGLTVLWPHHQDFQSYPK", "length": 398 }, "evidence": [ { "id": "A0A8V0YN49", "url": "https://omabrowser.org/oma/group/A0A8V0YN49/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P27931-1", "protein_name": "Interleukin-1 receptor type 2", "gene_name": "Il1r2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFILLVLVTGVSAFTTPTVVHTGKVSESPITSEKPTVHGDNCQFRGREFKSELRLEGEPVVLRCPLAPHSDISSSSHSFLTWSKLDSSQLIPRDEPRMWVKGNILWILPAVQQDSGTYICTFRNASHCEQMSVELKVFKNTEASLPHVSYLQISALSTTGLLVCPDLKEFISSNADGKIQWYKGAILLDKGNKEFLSAGDPTRLLISNTSMDDAGYYRCVMTFTYNGQEYNITRNIELRVKGTTTEPIPVIISPLETIPASLGSRLIVPCKVFLGTGTSSNTIVWWLANSTFISAAYPRGRVTEGLHHQYSENDENYVEVSLIFDPVTREDLHTDFKCVASNPRSSQSLHTTVKEVSSTFSWSIALAPLSLIILVVGAIWMRRRCKRRAGKTYGLTKLRTDNQDFPSSPN", "length": 410 }, "evidence": [ { "id": "A0A8V0YN49", "url": "https://omabrowser.org/oma/group/A0A8V0YN49/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P43303-1", "protein_name": "Interleukin-1 receptor type 2", "gene_name": "Il1r2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFILLVLVTGVSAFTTPAVVHTGRVSESPVTSEKHPVLGDDCWFRGRDFKSELRLEGEPVVLRCPLVPHSDTSSSSRSLLTWSKSDSSQLIPGDEPRMWVKDDTLWVLPAVQQDSGTYICTFRNASHCEQMSLELKVFKNTEASFPLVSYLQISALSSTGLLVCPDLKEFISSRTDGKIQWYKGSILLDKGNKKFLSAGDPTRLLISNTSMGDAGYYRCVMTFTYEGKEYNITRNIELRVKGITTEPIPVIISPLETIPASLGSRLIVPCKVFLGTGTSSNTIVWWMANSTFISVAYPRGRVTEGLHHQYSENDENYVEVSLIFDPVTKEDLNTDFKCVATNPRSFQSLHTTVKEVSSTFSWGIALAPLSLIILVVGAIWIRRRCKRQAGKTYGLTKLPTDNQDFPSSPNQIKEMK", "length": 416 }, "evidence": [ { "id": "A0A8V0YN49", "url": "https://omabrowser.org/oma/group/A0A8V0YN49/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "inflammatory response", "id": "GO:0006954", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006954", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YN49", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN49" } ], "pmid": "" }, { "name": "cell surface receptor signaling pathway", "id": "GO:0007166", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007166", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YN49", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN49" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YN49", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN49" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YN49", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN49" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YN49", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN49" } ], "pmid": "" }, { "name": "cell surface", "id": "GO:0009986", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009986", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YN49", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN49" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "interleukin-1, type II, blocking receptor activity", "id": "GO:0004910", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004910", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YN49", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN49" } ], "pmid": "" }, { "name": "interleukin-1 binding", "id": "GO:0019966", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019966", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YN49", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN49" } ], "pmid": "" }, { "name": "interleukin-1 receptor activity", "id": "GO:0004908", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004908", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YN49", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN49" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 125, "end_pos": 127, "annotation": "n_glycosylation_sequon" }, { "start_pos": 131, "end_pos": 133, "annotation": "n_glycosylation_sequon" }, { "start_pos": 172, "end_pos": 174, "annotation": "n_glycosylation_sequon" }, { "start_pos": 219, "end_pos": 221, "annotation": "n_glycosylation_sequon" }, { "start_pos": 336, "end_pos": 338, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YN49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN49" }, { "id": "PS50835", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50835" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ig-like", "eco_id": "ECO_0000259", "start_pos": 88, "end_pos": 184, "start_aa": "Pro", "end_aa": "Thr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 125, "end_pos": 127 }, { "start_pos": 131, "end_pos": 133 }, { "start_pos": 172, "end_pos": 174 }, { "start_pos": 219, "end_pos": 221 }, { "start_pos": 336, "end_pos": 338 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": 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"n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YMT1-1", "uniprot_ac": "A0A8V0YMT1", "uniprot_id": "A0A8V0YMT1_CHICK", "mass": { "chemical_mass": 55148.0, "monoisotopic_mass": 55148.0 }, "refseq": {}, "gene_names": [ { "name": "PAFAH2", "type": "recommended", "evidence": [ { "id": "A0A8V0YMT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMT1" } ] } ], "protein_names": [ { "name": "1-alkyl-2-acetylglycerophosphocholine esterase", "type": "recommended", "evidence": [ { "id": "A0A8V0YMT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMT1/entry#names_and_taxonomy" } ] }, { "name": "3.1.1.47", "type": "synonym", "evidence": [ { "id": "A0A8V0YMT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMT1/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMT1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMT1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PAFAH2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMT1", "locus": { "chromosome": "23", "start_pos": 3598397, "end_pos": 3591974, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013502", "url": "https://www.ensembl.org/id/ENSGALG00010013502" } ] } } ], "crossref": [ { "id": "A0A8V0YMT1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YMT1", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR029058", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029058", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YKX3", "url": "https://www.orthodb.org/?gene=A0A8V0YKX3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YMT1", "url": "https://www.orthodb.org/?gene=A0A8V0YMT1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YSS1", "url": "https://www.orthodb.org/?gene=A0A8V0YSS1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10272", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10272", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10272:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10272:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03403", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03403", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-418346", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-418346", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YKX3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKX3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YKX3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKX3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YMT1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMT1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YMT1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMT1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YSS1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSS1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YSS1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSS1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGSPCSRGYVNTLKPFWQREASKQLSMRHRLPWDVLSCATRRARGEGCAVSVLPCSSQGSAKLCSRVRSAQRGQLLRTATFLLGKKVKRRSCSLPKKKSRSQEARKVRKRLGCGAMGGEQSLALPPEKGPHRVGCADIMVGHTQQGLFFRLFYPCVPRDGAERPLWIPRYEYCSGLADFSGHSRRWCAPLLSIAIGSCRVPLSWKAPFKPCSSGYPLIIFSHGLGAFRTVYSSICMQMASWGFVVAALEHRDSSAAMTYFCTAEAVREQWIPHQQVPQGQKEFYFRNNQVHHRANECARALQLFRDISRGNSIPNVLPQGFDLSVLKDSIDLAKAAVMGHSFGGVTAVLALVKEPGFRCAVALDAWMFPLENVLYPEVPKPVLFINTEKFQTPESVAKMKRLSSRNSQTKIITILGSVHQSQTDFAFLTGKLINRVFHARGTLDPSKCLDITSQAALAFLQRHLGVREEFARWDRLLEGIGDSVIPEAPFFLSNL", "length": 495, "header": "tr|A0A8V0YMT1-1|A0A8V0YMT1_CHICK Isoform 1 of 1-alkyl-2-acetylglycerophosphocholine esterase OS=Gallus gallus OX=9031 GN=PAFAH2 PE=1 SV=1 CANONICAL=A0A8V0YMT1-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YKX3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMT1/entry#A0A8V0YKX3-1", "sequence": { "sequence": "MWAWPAAPKGAPRIHFGTPTWPWGFPRCGGGSEGGVPGPSPRVSVPLIHPRSTPISASRVEVGHLRPAYRRLGCGAMGGEQSLALPPEKGPHRVGCADIMVGHTQQGLFFRLFYPCVPRDGAERPLWIPRYEYCSGLADFSGHSRRWCAPLLSIAIGSCRVPLSWKAPFKPCSSGYPLIIFSHGLGAFRTVYSSICMQMASWGFVVAALEHRDSSAAMTYFCTAEAVREQWIPHQQVPQGQKEFYFRNNQVHHRANECARALQLFRDISRGNSIPNVLPQGFDLSVLKDSIDLAKAAVMGHSFGGVTAVLALVKEPGFRCAVALDAWMFPLENVLYPEVPKPVLFINTEKFQTPESVAKMKRLSSRNSQTKIITILGSVHQSQTDFAFLTGKLINRVFHARGTLDPSKCLDITSQAALAFLQRHLATWLPSPGSNWQCLEDVGKCWLGSPWESCWLGLFPAPAK", "length": 464, "header": "tr|A0A8V0YKX3-1|A0A8V0YMT1_CHICK Computationally mapped isoform of 1-alkyl-2-acetylglycerophosphocholine esterase OS=Gallus gallus OX=9031 GN=PAFAH2 PE=1 SV=1 CANONICAL=A0A8V0YMT1-1" }, "locus": { "chromosome": "23", "start_pos": 3597989, "end_pos": 3593493, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032488.1", "url": "https://www.ensembl.org/id/ENSGALT00010032488.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019232.1", "url": "https://www.ensembl.org/id/ENSGALP00010019232.1" } ] } }, { "isoform_ac": "A0A8V0YMT1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMT1/entry#A0A8V0YMT1-1", "sequence": { "sequence": "MGSPCSRGYVNTLKPFWQREASKQLSMRHRLPWDVLSCATRRARGEGCAVSVLPCSSQGSAKLCSRVRSAQRGQLLRTATFLLGKKVKRRSCSLPKKKSRSQEARKVRKRLGCGAMGGEQSLALPPEKGPHRVGCADIMVGHTQQGLFFRLFYPCVPRDGAERPLWIPRYEYCSGLADFSGHSRRWCAPLLSIAIGSCRVPLSWKAPFKPCSSGYPLIIFSHGLGAFRTVYSSICMQMASWGFVVAALEHRDSSAAMTYFCTAEAVREQWIPHQQVPQGQKEFYFRNNQVHHRANECARALQLFRDISRGNSIPNVLPQGFDLSVLKDSIDLAKAAVMGHSFGGVTAVLALVKEPGFRCAVALDAWMFPLENVLYPEVPKPVLFINTEKFQTPESVAKMKRLSSRNSQTKIITILGSVHQSQTDFAFLTGKLINRVFHARGTLDPSKCLDITSQAALAFLQRHLGVREEFARWDRLLEGIGDSVIPEAPFFLSNL", "length": 495, "header": "tr|A0A8V0YMT1-1|A0A8V0YMT1_CHICK Isoform 1 of 1-alkyl-2-acetylglycerophosphocholine esterase OS=Gallus gallus OX=9031 GN=PAFAH2 PE=1 SV=1 CANONICAL=A0A8V0YMT1-1" }, "locus": { "chromosome": "23", "start_pos": 3598169, "end_pos": 3592173, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032495.1", "url": "https://www.ensembl.org/id/ENSGALT00010032495.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019238.1", "url": "https://www.ensembl.org/id/ENSGALP00010019238.1" } ] } }, { "isoform_ac": "A0A8V0YSS1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMT1/entry#A0A8V0YSS1-1", "sequence": { "sequence": "MWAWPAAPKGAPRIHFGTPTWPWGFPRCGGGSEGGVPGPSPRVSVPLIHPRSTPISASRVEVGHLRPAYRRLGCGAMGGEQSLALPPEKGPHRVGCADIMVGHTQQGLFFRLFYPCVPRDGAERPLWIPRYEYCSGLADFSGHSRRWCAPLLSIAIGSCRVPLSWKAPFKPCSSGYPLIIFSHGLGAFRTVYSSICMQMASWGFVVAALEHRDSSAAMTYFCTAEAVREQWIPHQQVPQGQKEFYFRNNQVHHRANECARALQLFRDISRGNSIPNVLPQGFDLSVLKDSIDLAKAAVMGHSFGGVTAVLALVKEPGFRCAVALDAWMFPLENVLYPEVPKPVLFINTEKFQTPESVAKMKRLSSRNSQTKIITILGSVHQSQTDFAFLTGKLINRVFHARGTLDPSKCLDITSQAALAFLQRHLGMAQVELDGAWEGTRLV", "length": 442, "header": "tr|A0A8V0YSS1-1|A0A8V0YSS1_CHICK Computationally mapped isoform of 1-alkyl-2-acetylglycerophosphocholine esterase OS=Gallus gallus OX=9031 GN=PAFAH2 PE=1 SV=1 CANONICAL=A0A8V0YMT1-1" }, "locus": { "chromosome": "23", "start_pos": 3597844, "end_pos": 3593493, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032492.1", "url": "https://www.ensembl.org/id/ENSGALT00010032492.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019236.1", "url": "https://www.ensembl.org/id/ENSGALP00010019236.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "R-GGA-418346", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-418346", "resource": "Reactome", "description": "Platelet homeostasis" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "lipid catabolic process", "id": "GO:0016042", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016042", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMT1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMT1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "1-alkyl-2-acetylglycerophosphocholine esterase activity", "id": "GO:0003847", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003847", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMT1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMT1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-GGA-8869206", "name": "PAFAH2 hydrolyses PAF to lyso-PAF and acetate", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, endoplasmic reticulum membrane", "input_participant_list": [ "R-ALL-8869214" ], "output_participant_list": [ "R-ALL-8869207" ], "enzyme_list": [ "A0A8V0YMT1-1" ], "evidence": [ { "id": "R-GGA-8869206", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8869206" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-8869207", "participant_name": "lyso-PAF [endoplasmic reticulum membrane]", "crossref": [ { "id": "ZINC000008860508", "database": "ZINC", "url": "" }, { "id": "91144", "database": "ChEBI", "url": "" }, { "id": "ZINC000014880842", "database": "ZINC", "url": "" } ] }, { "participant_id": "R-ALL-8869214", "participant_name": "PAF [endoplasmic reticulum membrane]", "crossref": [ { "id": "52450", "database": "ChEBI", "url": "" }, { "id": "ZINC000008214639", "database": "ZINC", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A0A8V0YMT1", "gene_name": "PAFAH2", "activity": [ { "ec_number": "3.1.1.47", "activity": "a 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine + H2O = a 1-O-alkyl-sn-glycero-3-phosphocholine + acetate + H(+).", "evidence": [ { "id": "A0A8V0YMT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMT1" } ] }, { "ec_number": "3.1.1.47", "activity": "", "evidence": [ { "id": "A0A8V0YMT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMT1" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "3.1.1.47", "ec_name": "a 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine + H2O = a 1-O-alkyl-sn-glycero-3-phosphocholine + acetate + H(+).", "evidence": [ { "id": "3.1.1.47", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.47" }, { "id": "3.1.1.47", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=3.1.1.47" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": 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"Protein" ] }, { "id": "A0A8V0YNM7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNM7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAAEGVEGGEREEEDEVEEQLVMVELSGIIDSDFLEKCENKCKILGIETERPILQVDRYVFAGDYEDALGTCVFFEENTEHGNDAEGNQKLQLKYKCHTMKKLNMTRTLLTEKKEGEESIGGVEWLQIKDRDFSYSRPNTICSFLHEQEDAEESAQAQEKLTEEAEGEVSDRGSSDLNCDPEQPRGLEADASSVPVPDSPASEAADSPSGSAALDDAPP", "length": 220, "header": "tr|A0A8V0YNM7-1|A0A8V0YNM7_CHICK Isoform 1 of General transcription factor 3C polypeptide 6 OS=Gallus gallus OX=9031 GN=GTF3C6 PE=1 SV=1 CANONICAL=A0A8V0YNM7-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YLD9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNM7/entry#A0A8V0YLD9-1", "sequence": { "sequence": "MAAAEGVEGGEREEEDEVEEQLVMVELSGIIDSDFLEKCENKCKILGIETERPILQVDRYVFAGDYEDAEGNQKLQLKYKCHTMKKLNMTRTLLTEKKEGEESIGGVEWLQIKDRDFSYSRPNTICSFLHEQEDAEESAQAQEKLTEEAEGEVSDRGSSDLNCDPEQPRGLEADASSVPVPDSPASEAADSPSGSAALDDAPP", "length": 203, "header": "tr|A0A8V0YLD9-1|A0A8V0YNM7_CHICK Computationally mapped isoform of General transcription factor 3C polypeptide 6 OS=Gallus gallus OX=9031 GN=GTF3C6 PE=1 SV=1 CANONICAL=A0A8V0YNM7-1" }, "locus": { "chromosome": "3", "start_pos": 66005969, "end_pos": 66000887, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033119.1", "url": "https://www.ensembl.org/id/ENSGALT00010033119.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019580.1", "url": "https://www.ensembl.org/id/ENSGALP00010019580.1" } ] } }, { "isoform_ac": "A0A8V0YNM7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNM7/entry#A0A8V0YNM7-1", "sequence": { "sequence": "MAAAEGVEGGEREEEDEVEEQLVMVELSGIIDSDFLEKCENKCKILGIETERPILQVDRYVFAGDYEDALGTCVFFEENTEHGNDAEGNQKLQLKYKCHTMKKLNMTRTLLTEKKEGEESIGGVEWLQIKDRDFSYSRPNTICSFLHEQEDAEESAQAQEKLTEEAEGEVSDRGSSDLNCDPEQPRGLEADASSVPVPDSPASEAADSPSGSAALDDAPP", "length": 220, "header": "tr|A0A8V0YNM7-1|A0A8V0YNM7_CHICK Isoform 1 of General transcription factor 3C polypeptide 6 OS=Gallus gallus OX=9031 GN=GTF3C6 PE=1 SV=1 CANONICAL=A0A8V0YNM7-1" }, "locus": { "chromosome": "3", "start_pos": 66005969, "end_pos": 66000887, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033125.1", "url": "https://www.ensembl.org/id/ENSGALT00010033125.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019584.1", "url": "https://www.ensembl.org/id/ENSGALP00010019584.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-76061", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-76061", "resource": "Reactome", "description": "RNA Polymerase III Transcription Initiation From Type 1 Promoter" }, { "id": "R-GGA-76066", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-76066", "resource": "Reactome", "description": "RNA Polymerase III Transcription Initiation From Type 2 Promoter" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "transcription by RNA polymerase III", "id": "GO:0006383", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006383", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNM7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNM7" } ], "pmid": "" }, { "name": "transcription initiation at RNA polymerase III promoter", "id": "GO:0006384", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006384", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNM7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNM7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "transcription factor TFIIIC complex", "id": "GO:0000127", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000127", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNM7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNM7" } ], "pmid": "" }, { "name": "nuclear body", "id": "GO:0016604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016604", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNM7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNM7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNM7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNM7" } ], "pmid": "" }, { "name": "RNA polymerase III general transcription initiation factor activity", "id": "GO:0000995", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000995", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNM7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNM7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 105, "end_pos": 107, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], 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"count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YNN2-1", "uniprot_ac": "A0A8V0YNN2", "uniprot_id": "A0A8V0YNN2_CHICK", "mass": { "chemical_mass": 55147.0, "monoisotopic_mass": 55147.0 }, "refseq": {}, "gene_names": [ { "name": "PYROXD1", "type": "recommended", "evidence": [ { "id": "A0A8V0YNN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNN2" } ] } ], "protein_names": [ { "name": "tRNA ligase complex-associated NAD(P)H dehydrogenase PYROXD1", "type": "recommended", "evidence": [ { "id": "A0A8V0YNN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNN2/entry#names_and_taxonomy" } ] }, { "name": "1.6.99.1", "type": "synonym", "evidence": [ { "id": "A0A8V0YNN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNN2/entry#names_and_taxonomy" } ] }, { "name": "Pyridine nucleotide-disulfide oxidoreductase domain-containing protein 1", "type": "synonym", "evidence": [ { "id": "A0A8V0YNN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNN2/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Flavoprotein whose role is to protect RTCB, the catalytic subunit of the tRNA ligase complex (tRNA-LC) involved in tRNA splicing and unfolded protein response, from oxidative inactivation. It directly binds and shields the catalytic center of RTCB, prior to guanylylation, when it is inactive and its active site is vulnerable to oxidation under aerobic conditions. The interaction of PYROXD1 with RTCB is allosterically regulated by NAD(P)H binding and reduction of its FAD cofactor, while reoxidation of PYROXD1 thanks to its NADPH dehydrogenase activity triggers the timed release of RTCB, enabling its subsequent activation. Thereby, this protective mechanism may also function as a molecular timer, regulating RTCB activation through controlled release.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YLV3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLV3#function" }, { "database": "UniProtKB", "id": "ARBA00094509", "url": "https://www.uniprot.org/uniprotkb/ARBA00094509#function" }, { "database": "UniProtKB", "id": "A0A8V0YNN2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNN2#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNN2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNN2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PYROXD1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNN2", "locus": { "chromosome": "1", "start_pos": 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YPA0-1", "uniprot_ac": "A0A8V0YPA0", "uniprot_id": "A0A8V0YPA0_CHICK", "mass": { "chemical_mass": 164382.0, "monoisotopic_mass": 164382.0 }, "refseq": { "ac": "NP_001335489", "name": "inositol 1,4,5-triphosphate receptor associated 2 isoform 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001335489" }, "gene_names": [ { "name": "IRAG2", "type": "recommended", "evidence": [ { "id": "A0A8V0YPA0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPA0" } ] }, { "name": "IRAG2", "type": "synonym", "evidence": [ { "id": "NP_001335489", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001335489" } ] }, { "name": "LRMP", "type": "synonym", "evidence": [ { "id": "NP_001335489", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001335489" } ] } ], "protein_names": [ { "name": "Inositol 1,4,5-triphosphate receptor associated 2", "type": "synonym", "evidence": [ { "id": "A0A8V0YPA0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPA0/entry#names_and_taxonomy" } ] }, { "name": "inositol 1,4,5-triphosphate receptor associated 2 isoform 1", "type": "synonym", "evidence": [ { "id": "NP_001335489", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001335489" } ] }, { "name": "lymphoid restricted membrane protein", "type": "synonym", "evidence": [ { "id": "NP_001335489", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001335489" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMEA103992290, SAMN06140853 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000012.1. On Dec 3, 2021 this sequence version replaced NP_001335489.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001335489", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001335489" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPA0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPA0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "IRAG2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPA0", "locus": { "chromosome": "1", "start_pos": 67241411, "end_pos": 67203345, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010014019", "url": "https://www.ensembl.org/id/ENSGALG00010014019" } ] } } ], "crossref": [ { "id": "ENSGALG00000014011", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000014011", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "418205", "url": "https://www.ncbi.nlm.nih.gov/gene/418205", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR008677", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008677", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028168", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028168", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039508", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039508", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:418205", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418205", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "EWMAYCG", "url": "https://omabrowser.org/oma/group/EWMAYCG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YPA0", "url": "https://www.orthodb.org/?gene=A0A8V0YPA0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15352", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15352", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15352:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15352:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05781", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05781", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14658", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14658", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14662", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14662", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-6798695", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6798695", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001335489", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001335489", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q2UG37", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UG37", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2UG37-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UG37-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YM18", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM18", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YM18-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM18-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YM23", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM23", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YM23-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM23-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YPA0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPA0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YPA0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPA0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSSERATNKRHHNPVDSICRKIKSIQMMDQVSNPALQIPKFQSRSFDSPQCNVKKNLEEILKKRTFRSRNSTSPPYFSPSSDSVSSADLQLLSPCSRRISDCSSADATYSAIKREERTSNQWLPVCPMDNCSPPYFMSREESAQNQRCALASIESEDVHREQKYITSSPHLLLFTSDKRLESPAVQHPMPKRLPLSERGQKQSSVLQPCDMCDVSLICEEDLLTTIFHACDVKHTGKVAVSKIVDYLRHTTSRGLEDSGLEELCNMLDPDQKDVSVDLETYHAIMKEWIEDCKRKWDDSATEEPTSSIEDLEFKVHRNNFEVKKTPLWMNVTSGSLEAFGGDVSKGDMETSDLITCVADLQYNNLKLQEENNKLKLTLEAVDETNNKLLADNENLCQQIKSIQHSVLKAKSLEEELEEAKNNLNLLEEKGQKMLCQNKQLEKENQSLVIKIASLQEENIRNSMDTDGLQKKILDLSKSAAELQMQVHIYESTVVNKEASLIQKEQDIKELKLTIVECSSIIETLRAEKSKLLEDMRHMQQELISNGLSFPLMSKVNGSIPEEMNSLDCELELAQSSEITKTEWMSLDETLDREVLFLLQGPEHAGEKFKAVMQNLVSGLAYQEEASAAEELVRTSLQWVEDPDVNVQQAWERKLVVLKQELGEKRHLWIQKLNLLEKYKESLDKDFIRMASNLRRTKTEQLHLRKELSARQREIETVKQLQEEAAGQAEALGLELQKATKQLEDASKQREDQAEAFHSACEEAISLKCKLKEAISEQQKLKDVNAALTGTCRLLQEKMEEQKTTVIALRGELLRERLCERLYQLCVGEESVYSLLPTLAEPVKGKQLCYPKRLWSEGPSSCTEFPRTLPSDTSYCGLTPLLDALNLETSCLINFPVHSWNPPCRQSSVTCLSESCGLWHASISDVTSVGCKWKIYSAGGCTDSDLPVSITMMDSSLTEMDHAEPSIPLGLIPSSDRLTSPQEVLASSSESTAPVTGCLAMEEKSPKYSCAKEEVVPASVTMERNNDQDAAGSVSEADLIKKDSTSTMEEHKADPIKKDLEMENEATKEQSEVTPAVVPSRKGSSPAAGGLKGDKAKQNEPDSPSEKEVEAEFLRLSLGFKCDLFTLDKRVRLEERSRELAEENLKKEITNALKMLEALVPLCEEDNQAQEIIKKLQKSLQFLSQYAARVASRAEMLGAINQESRISKAVEVMIQHVENLKRMYTKEHAELEELKQVLLQNERSFSSLGDRDESTNKKLPNSFNFKPSPSLRRVSIATLPRSAGNAGVGVPLAQLHEAGGDEWSDKFNRRSSSWGRLGARQNEKRPSLQRFISTYSWTEYEDEHSETKNEQLELPAEMQEQLARKESTSEKGKCPSKWNLKSACNLVSSWASHFKTSFSNANKTLWVSVSILVLLAAFTSFLTGLSLQRPADAAPVGTGDSWTSLQQLLWPYTGLQHNGPPPV", "length": 1462, "header": "tr|A0A8V0YPA0-1|A0A8V0YPA0_CHICK Isoform 1 of Inositol 1,4,5-triphosphate receptor associated 2 OS=Gallus gallus OX=9031 GN=IRAG2 PE=4 SV=1 CANONICAL=A0A8V0YPA0-1" }, "isoforms": [ { "isoform_ac": "A0A3Q2UG37-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPA0/entry#A0A3Q2UG37-1", "sequence": { "sequence": "MCLRQCISLLFRQYANKMCIARWKIYSAGGCTDSDLPVSITMMDSSLTEMDHAEPSIPLGLIPSSDRLTSPQEVLASSSESTAPVTGCLAMEEKSPKYSCAKEEVVPASVTMERNNDQDAAGSVSEADLIKKDSTSTMEEHKADPIKKDLEMENEATKEQSEVTPAVVPSRKGSSPAAGGLKGDKAKQNEPDSPSEKEVEAEFLRLSLGFKCDLFTLDKRVRLEERSRELAEENLKKEITNALKMLEALVPLCEEDNQAQEIIKKLQKSLQFLSQYAARVASRAEMLGAINQESRISKAVEVMIQHVENLKRMYTKEHAELEELKQVLLQNERSFSSLGDRDESTNKKLPNSFNFKAQLHEAGGDEWSDKFNRRSSSWGRLGARQNEKRPSLQRFISTYSWTEYEDEHSETKNEQLELPAEMQEQLARKESTSEKGKCPSKWNLKSACNLVSSWASHFKTSFSNANKTLWVSVSILVLLAAFTSFLTGLSLQRPADAAPVGTGDSWTSLQQLLWPYTGLQHNGPPPV", "length": 527, "header": "tr|A0A3Q2UG37-1|A0A3Q2UG37_CHICK Computationally mapped isoform of Inositol 1,4,5-triphosphate receptor associated 2 OS=Gallus gallus OX=9031 GN=IRAG2 PE=4 SV=1 CANONICAL=A0A8V0YPA0-1" }, "locus": { "chromosome": "1", "start_pos": 67240965, "end_pos": 67228181, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033644.1", "url": "https://www.ensembl.org/id/ENSGALT00010033644.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019810.1", "url": "https://www.ensembl.org/id/ENSGALP00010019810.1" } ] } }, { "isoform_ac": "A0A8V0YM18-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPA0/entry#A0A8V0YM18-1", "sequence": { "sequence": "MMELSKQSMLLKLFPVKTILCVGEESVYSLLPTLAEPVKGKLCYPKRLWSEGPSSCTEFPRTLPSDTSYCGLTPLLDALNLETSCLINFPVHSWNPPCRQSSVTCLSESCGLWHASISDVTSVGCKWKIYSAGGCTDSDLPVSITMMDSSLTEMDHAEPSIPLGLIPSSDRLTSPQEVLASSSESTAPVTGCLAMEEKSPKYSCAKEEVVPASVTMERNNDQDAAGSVSEADLIKKDSTSTMEEHKADPIKKDLEMENEATKEQSEVTPAVVPSRKGSSPAAGGLKGDKAKQNEPDSPSEKEVEAEFLRLSLGFKCDLFTLDKRVRLEERSRELAEENLKKEITNALKMLEALVPLCEEDNQAQEIIKKLQKSLQFLSQYAARVASRAEMLGAINQESRISKAVEVMIQHVENLKRMYTKEHAELEELKQVLLQNERSFSSLGDRDESTNKKLPNSFNFKAQLHEAGGDEWSDKFNRRSSSWGRLGARQNEKRPSLQRFISTYSWTEYEDEHSETKNEQLELPAEMQEQLARKESTSEKGKCPSKWNLKSACNLVSSWASHFKTSFSNANKTLWVSVSILVLLAAFTSFLTGLSLQRPADAAPVGTGDSWTSLQQLLWPYTGLQHNGPPPV", "length": 631, "header": "tr|A0A8V0YM18-1|A0A8V0YPA0_CHICK Computationally mapped isoform of Inositol 1,4,5-triphosphate receptor associated 2 OS=Gallus gallus OX=9031 GN=IRAG2 PE=4 SV=1 CANONICAL=A0A8V0YPA0-1" }, "locus": { "chromosome": "1", "start_pos": 67240965, "end_pos": 67224135, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033623.1", "url": "https://www.ensembl.org/id/ENSGALT00010033623.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019800.1", "url": "https://www.ensembl.org/id/ENSGALP00010019800.1" } ] } }, { "isoform_ac": "A0A8V0YM23-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPA0/entry#A0A8V0YM23-1", "sequence": { "sequence": "MCLRQCISLLFRQYANKMCIARWKIYSAGGCTDSDLPVSITMMDSSLTEMDHAEPSIPLGLIPSSDRLTSPQEVLASSSESTAPVTGCLAMEEKSPKYSCAKEEVVPASVTMERNNDQDAAGSVSEADLIKKDSTSTMEEHKADPIKKDLEMENEATKEQSEVTPAVVPSRKGSSPAAGGLKGDKAKQNEPDSPSEKEVEAEFLRLSLGFKCDLFTLDKRVRLEERSRELAEENLKKEITNALKMLEALVPLCEEDNQAQEIIKKLQKSLQFLSQYAARVASRAEMLGAINQESRISKAVEVMIQHVENLKRMYTKEHAELEELKQVLLQNERSFSSLGDRDESTNKKLPNSFNFKPSPSLRRVSIATLPRSAGNAGVGVPLAQLHEAGGDEWSDKFNRRSSSWGRLGARQNEKRPSLQRFISTYSWTEYEDEHSETKNEQLELPAEMQEQLARKESTSEKGKCPSKWNLKSACNLVSSWASHFKTSFSNANKTLWVSVSILVLLAAFTSFLTGLSLQRPADAAPVGTGDSWTSLQQLLWPYTGLQHNGPPPV", "length": 553, "header": "tr|A0A8V0YM23-1|A0A8V0YPA0_CHICK Computationally mapped isoform of Inositol 1,4,5-triphosphate receptor associated 2 OS=Gallus gallus OX=9031 GN=IRAG2 PE=4 SV=1 CANONICAL=A0A8V0YPA0-1" }, "locus": { "chromosome": "1", "start_pos": 67240965, "end_pos": 67228181, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033633.1", "url": "https://www.ensembl.org/id/ENSGALT00010033633.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019806.1", "url": "https://www.ensembl.org/id/ENSGALP00010019806.1" } ] } }, { "isoform_ac": "A0A8V0YPA0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPA0/entry#A0A8V0YPA0-1", "sequence": { "sequence": "MSSERATNKRHHNPVDSICRKIKSIQMMDQVSNPALQIPKFQSRSFDSPQCNVKKNLEEILKKRTFRSRNSTSPPYFSPSSDSVSSADLQLLSPCSRRISDCSSADATYSAIKREERTSNQWLPVCPMDNCSPPYFMSREESAQNQRCALASIESEDVHREQKYITSSPHLLLFTSDKRLESPAVQHPMPKRLPLSERGQKQSSVLQPCDMCDVSLICEEDLLTTIFHACDVKHTGKVAVSKIVDYLRHTTSRGLEDSGLEELCNMLDPDQKDVSVDLETYHAIMKEWIEDCKRKWDDSATEEPTSSIEDLEFKVHRNNFEVKKTPLWMNVTSGSLEAFGGDVSKGDMETSDLITCVADLQYNNLKLQEENNKLKLTLEAVDETNNKLLADNENLCQQIKSIQHSVLKAKSLEEELEEAKNNLNLLEEKGQKMLCQNKQLEKENQSLVIKIASLQEENIRNSMDTDGLQKKILDLSKSAAELQMQVHIYESTVVNKEASLIQKEQDIKELKLTIVECSSIIETLRAEKSKLLEDMRHMQQELISNGLSFPLMSKVNGSIPEEMNSLDCELELAQSSEITKTEWMSLDETLDREVLFLLQGPEHAGEKFKAVMQNLVSGLAYQEEASAAEELVRTSLQWVEDPDVNVQQAWERKLVVLKQELGEKRHLWIQKLNLLEKYKESLDKDFIRMASNLRRTKTEQLHLRKELSARQREIETVKQLQEEAAGQAEALGLELQKATKQLEDASKQREDQAEAFHSACEEAISLKCKLKEAISEQQKLKDVNAALTGTCRLLQEKMEEQKTTVIALRGELLRERLCERLYQLCVGEESVYSLLPTLAEPVKGKQLCYPKRLWSEGPSSCTEFPRTLPSDTSYCGLTPLLDALNLETSCLINFPVHSWNPPCRQSSVTCLSESCGLWHASISDVTSVGCKWKIYSAGGCTDSDLPVSITMMDSSLTEMDHAEPSIPLGLIPSSDRLTSPQEVLASSSESTAPVTGCLAMEEKSPKYSCAKEEVVPASVTMERNNDQDAAGSVSEADLIKKDSTSTMEEHKADPIKKDLEMENEATKEQSEVTPAVVPSRKGSSPAAGGLKGDKAKQNEPDSPSEKEVEAEFLRLSLGFKCDLFTLDKRVRLEERSRELAEENLKKEITNALKMLEALVPLCEEDNQAQEIIKKLQKSLQFLSQYAARVASRAEMLGAINQESRISKAVEVMIQHVENLKRMYTKEHAELEELKQVLLQNERSFSSLGDRDESTNKKLPNSFNFKPSPSLRRVSIATLPRSAGNAGVGVPLAQLHEAGGDEWSDKFNRRSSSWGRLGARQNEKRPSLQRFISTYSWTEYEDEHSETKNEQLELPAEMQEQLARKESTSEKGKCPSKWNLKSACNLVSSWASHFKTSFSNANKTLWVSVSILVLLAAFTSFLTGLSLQRPADAAPVGTGDSWTSLQQLLWPYTGLQHNGPPPV", "length": 1462, "header": "tr|A0A8V0YPA0-1|A0A8V0YPA0_CHICK Isoform 1 of Inositol 1,4,5-triphosphate receptor associated 2 OS=Gallus gallus OX=9031 GN=IRAG2 PE=4 SV=1 CANONICAL=A0A8V0YPA0-1" }, "locus": { "chromosome": "1", "start_pos": 67240965, "end_pos": 67204999, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033659.1", "url": "https://www.ensembl.org/id/ENSGALT00010033659.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019820.1", "url": "https://www.ensembl.org/id/ENSGALP00010019820.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:418205", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418205", "resource": "KEGG Pathway" }, { "id": "R-GGA-6798695", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6798695", "resource": "Reactome", "description": "Neutrophil degranulation" } ], "orthologs": [ { "uniprot_canonical_ac": "Q12912-1", "protein_name": "Inositol 1,4,5-triphosphate receptor associated 2", "gene_name": "IRAG2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MESTPFSGVANQIHTLCERPTYGEVKDGALDVKRQHKCPGPTSGPSPGTNLSGCIRMNDDPSMEENGVERVCPESLLQSREYSSLPLPRHTSSTDGTITSSDPGLEILNMASCDLDRNSLCKKEEDTRSASPTIEAQGTSPAHDNIAFQDSTSKDKTILNLEAKEEPETIEEHKKEHASGDSVVSPLPVTTVKSVNLRQSENTSANEKEVEAEFLRLSLGFKCDWFTLEKRVKLEERSRDLAEENLKKEITNCLKLLESLTPLCEDDNQAQEIIKKLEKSIKFLSQCAARVASRAEMLGAINQESRVSKAVEVMIQHVENLKRMYAKEHAELEELKQVLLQNERSFNPLEDDDDCQIKKRSASLNSKPSSLRRVTIASLPRNIGNAGMVAGMENNDRFSRRSSSWRILGSKQSEHRPSLPRFISTYSWADAEEEKCELKTKDDSEPSGEETVERTRKPSLSEKKNNPSKWDVSSVYDTIASWATNLKSSIRKANKALWLSIAFIVLFAALMSFLTGQLFQKSVDAAPTQQEDSWTSLEHILWPFTRLRHNGPPPV", "length": 555 }, "evidence": [ { "id": "A0A8V0YPA0", "url": "https://omabrowser.org/oma/group/A0A8V0YPA0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q5RHB5-1", "protein_name": "Inositol 1,4,5-triphosphate receptor associated 2", "gene_name": "irag2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDVGVTPRRHNPVDSICRKLQTIQRRDQEINSPFQIPKFQTNSYDSPHSGLRFNLEAILKKHTVRPDDSDSASSAGMLTPTASPGPGSSCNTPRAPITPVNATYSITSTLGTLGTIGDRRTSGTYSRPFRRNCSTPSAQTGDNYFNFTPRYSTQSQGPDTDVRTSKIPTPGLFSYNLNFSSDISNMDSELAYPALVVKRLSLGEGSLFTSEPKKESMAEVSLICEEDLLDTIFQACDTQCRGKVYVSHIVDFLRHTTCRSSEDSGLEELCNMLDPERKDISIDLDTYHAIMKEWIEDCRNQGKDLKNDTQQESSKLRDSLSAKRSALLNMTSGSLEAFGGEASRADLETSDLVFCVADLQLNNQKLQEEVRKLKQAVENMEDTNQKLIEENEELKTQAKMGQQLLQKEKMLKEEVEEMKLSLTSSEESRAQAAAQRKQMERENQSLISKIAALQEENMKVTLEAEELQKKMNDLCDLNADLQVQIHSFDAILADKESLIQEKNKQMDELKVAVVEYSSVTELLRADKNKLESQMQMMQPDVTIPGLSLSVAYRLNQTSSGSLQTELALAQNPLEGLEHLSTSVCFASSLDETLDREVLLLLQGPTPEQLSLEFKSLISRLKREFKEDGLTFLTAIRSLTENSETQEANTDLKMQGLEVQLEQRRTDWIRSLEQLDQYRDSLERELLKMASNMRRSRTEILHLSVKVQEQENQKQQLREEVDRLKTPLDNREASSQTPDHLQQVVEELDGPSLEWDEEYVLSESPPLQELGPDQQMLEELCCDEEVLQALKQEEEEPTETVSDKEKITAKSEGEGEATYDSGVENEEPQRDFTLSHMCLPDKKSERESNEAPFVGEGGEQRPCMSLKEEDRLPECTGPEDAHEQAAPLPHTHCECAGDQPLTYDNLEVTSVKDHILSTEPSSLMTCELVSPSTGHPEVGNSITGRTEQLVGTNGEPEEERLTTGADMSDLQRLGEGQLSKVSAKSDKSLLLPVAEEEEAMPEAVEVTSAGVNSPDKHKTGSKKTVVTSDSNSTGSADSLKDPSEKVKDMTFDPAASEDNIPTVPATQSPKKDPLASRNKLKKEMSSMEVIEEQKAQEDGEPTVVTEKEGDTSVSSENASDSTKDDKNSLSPSDKEIEAEFHRLSLGFKCDMFTLEKRLRLEERSRDLAEENVRKEVISCKALLQALIPRCEEDNQSMEIIHRVQKNLEILVQSMTRVSSRSEMLGAIHQETRVGKTVEVMIQHVENLRRMYTKEHAELLELRENLTPNERSFGSHSERDDFRNKKQTTSNIFKTTSRRISIATIPRSIGGQTHFDMPKDMAETEVERLSRRSPWNMAAKRPPLKRFVSSGTWADIDEPTLMNSPTPSPTDNAPPSLMEGRPAVSRGARGIWIWVALFVVLAVLLALLASLMLQPAVDAAPVGTGDSWMTIQQLLWPYTGLRHNGQPPV", "length": 1447 }, "evidence": [ { "id": "A0A8V0YPA0", "url": "https://omabrowser.org/oma/group/A0A8V0YPA0/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPA0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPA0" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPA0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPA0" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPA0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPA0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 130, "end_pos": 132, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1401, "end_pos": 1403, "annotation": "n_glycosylation_sequon" }, { "start_pos": 330, "end_pos": 332, "annotation": "n_glycosylation_sequon" }, { "start_pos": 444, "end_pos": 446, "annotation": "n_glycosylation_sequon" }, { "start_pos": 556, "end_pos": 558, "annotation": "n_glycosylation_sequon" }, { "start_pos": 70, "end_pos": 72, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YPA0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPA0" }, { "id": "PF14662", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14662" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "KASH5-like coiled-coil", "eco_id": "ECO_0000259", "start_pos": 349, "end_pos": 537, "start_aa": "Glu", "end_aa": "His", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0YPA0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPA0" }, { "id": "PF14658", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14658" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Protein KASH5 EF-hand-like", "eco_id": "ECO_0000259", "start_pos": 225, "end_pos": 289, "start_aa": "Thr", "end_aa": "Ile", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 130, "end_pos": 132 }, { "start_pos": 1401, "end_pos": 1403 }, { "start_pos": 330, "end_pos": 332 }, { "start_pos": 444, "end_pos": 446 }, { "start_pos": 556, "end_pos": 558 }, { "start_pos": 70, "end_pos": 72 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YNZ3-1", "uniprot_ac": "A0A8V0YNZ3", "uniprot_id": "A0A8V0YNZ3_CHICK", "mass": { "chemical_mass": 72350.0, "monoisotopic_mass": 72350.0 }, "refseq": {}, "gene_names": [ { "name": "DDO", "type": "recommended", "evidence": [ { "id": "A0A8V0YNZ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNZ3" } ] } ], "protein_names": [ { "name": "Solute carrier family 22 member 16", "type": "recommended", "evidence": [ { "id": "A0A8V0YNZ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNZ3/entry#names_and_taxonomy" } ] }, { "name": "Carnitine transporter 2", "type": "synonym", "evidence": [ { "id": "A0A8V0YNZ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNZ3/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Selectively catalyzes the oxidative deamination of acidic amino acids. Suppresses the level of D-aspartate in the brain, an amino acid that can act as an agonist for glutamate receptors. Protects the organism from the toxicity of D-amino acids. May also function in the intestine.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YTZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTZ7#function" }, { "database": "UniProtKB", "id": "ARBA00046214", "url": "https://www.uniprot.org/uniprotkb/ARBA00046214#function" }, { "database": "UniProtKB", "id": "A0A8V0YNY8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNY8#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNZ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNZ3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "DDO", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNZ3", "locus": {} } ], "crossref": [ { "id": "A0A8V0YNZ3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YNZ3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000015055", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000015055", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd17375", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd17375", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "770953", "url": "https://www.ncbi.nlm.nih.gov/gene/770953", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR005828", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005828", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006076", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006076", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006181", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006181", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011701", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011701", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020846", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020846", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023209", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023209", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036259", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036259", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:421757", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:421757", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "gga:770953", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:770953", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DLWELQP", "url": "https://omabrowser.org/oma/group/DLWELQP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "MEAYMGA", "url": "https://omabrowser.org/oma/group/MEAYMGA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PQX4", "url": "https://www.orthodb.org/?gene=A0A1D5PQX4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YM67", "url": "https://www.orthodb.org/?gene=A0A8V0YM67", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YNY8", "url": "https://www.orthodb.org/?gene=A0A8V0YNY8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YNZ3", "url": "https://www.orthodb.org/?gene=A0A8V0YNZ3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YTZ7", "url": "https://www.orthodb.org/?gene=A0A8V0YTZ7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11530", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11530", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11530:SF11", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11530:SF11", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24064", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24064", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00083", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00083", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01266", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01266", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07690", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07690", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-549127", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-549127", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "10028", "url": "https://www.rhea-db.org/rhea/10028", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "12512", "url": "https://www.rhea-db.org/rhea/12512", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A1D5PQX4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PQX4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PQX4-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PQX4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YM67", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM67", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YM67-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM67-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YNY8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNY8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YNY8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNY8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YNZ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNZ3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YNZ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNZ3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YTZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTZ7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YTZ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTZ7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASGSEQLFDSLGHFGRFQACVYFASVFQAMSCGIHYLASVFMAVTPNFVCGIPGNVSSILFYNSSKASLEDIWTMWTSTENYIVAQLENGEIWELNQCSKSKREVSFDLAYEYKGNKSIFSCSDGFLYDVTKWKSTVVTQWDLVCDREWLAKLIQPTFMLGVLVGAVIFGDIADRLGRQRVMWFTSAGQFVFGITVAFTFDYYSFVIVRFLLAMVSSGYLVVAFVYVTEFVGIKARTWASMHVHAFFALGIMVVALVGFLVRTWWVYQIFLSIATLPFVLCCWMLPETPLWLLSQKRYEDAQKVINIMARWNKVSTPCKVSELCSVQQDDPGTDRTSGNATSSTKKHNILDLFCNWYIARRTITIWLVWFTGSLGYYVFSLSSVNLGGNEYLNLFLIGAVELPCYIIACIGMDKLGRRNTLIPFLILSALICVLIMFIPQDFNVLIILANMAGKFSIGVAFGLIYLYTAELYPTIVRSLAVGSGSMMCRVGSVVAPFCVYLRSVWIFLPLRISSCTIILAKLFLLLFITEGKSATKKQSVLEQQRDNCPLWLGSCGLQQHEQPLPAHTPDSFCSVGISQHQTSSPVKIPSEPGKSAVKPKPLLSCSSPFFPSHREVPVSANPHPTDGSPQGGSSGRGAYRTVHSVTYC", "length": 649, "header": "tr|A0A8V0YNZ3-1|A0A8V0YNZ3_CHICK Isoform 1 of Solute carrier family 22 member 16 OS=Gallus gallus OX=9031 GN=DDO PE=3 SV=1 CANONICAL=A0A8V0YNZ3-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PQX4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNZ3/entry#A0A1D5PQX4-1", "sequence": { "sequence": "MSCGIHYLASVFMAVTPNFVCGIPGNVSSILFYNSSKASLEDIWTMWTSTENYIVAQLENGEIWELNQCSKSKREVSFDLAYEYKGNKSIFSCSDGFLYDVTKWKSTVVTQWDLVCDREWLAKLIQPTFMLGVLVGAVIFGDIADRLGRQRVMWFTSAGQFVFGITVAFTFDYYSFVIVRFLLAMVSSGYLVVAFVYVTEFVGIKARTWASMHVHAFFALGIMVVALVGFLVRTWWVYQIFLSIATLPFVLCCWMLPETPLWLLSQKRYEDAQKVINIMARWNKVSTPCKVSELCSVQQDDPGTDRTSGNATSSTKKHNILDLFCNWYIARRTITIWLVWFTGSLGYYVFSLSSVNLGGNEYLNLFLIGAVELPCYIIACIGMDKLGRRNTLIPFLILSALICVLIMFIPQDFNVLIILANMAGKFSIGVAFGLIYLYTAELYPTIVRSLAVGSGSMMCRVGSVVAPFCVYLRSVWIFLPLLLVGIMALLSGILTLMLPETLGKPLTNTLEEATEMGRKKENYSGKTPPADSGAALEKIEMFGQETVSTEK", "length": 551, "header": "tr|A0A1D5PQX4-1|A0A1D5PQX4_CHICK Computationally mapped isoform of Solute carrier family 22 member 16 OS=Gallus gallus OX=9031 GN=DDO PE=3 SV=1 CANONICAL=A0A8V0YNZ3-1" }, "locus": { "chromosome": "3", "start_pos": 66243293, "end_pos": 66230215, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033394.1", "url": "https://www.ensembl.org/id/ENSGALT00010033394.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019700.1", "url": "https://www.ensembl.org/id/ENSGALP00010019700.1" } ] } }, { "isoform_ac": "A0A8V0YM67-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNZ3/entry#A0A8V0YM67-1", "sequence": { "sequence": "MASGSEQLFDSLGHFGRFQACVYFASVFQAMSCGIHYLASVFMAVTPNFVCGIPGNVSSILFYNSSKASLEDIWTMWTSTENYIVAQLENGEIWELNQCSKSKREVSFDLAYEYKGNKSIFSCSDGFLYDVTKWKSTVVTQWDLVCDREWLAKLIQPTFMLGVLVGAVIFGDIADRLGRQRVMWFTSAGQFVFGITVAFTFDYYSFVIVRFLLAMVSSGYLVVAFVYVTEFVGIKARTWASMHVHAFFALGIMVVALVGFLVRTWWVYQIFLSIATLPFVLCCWMLPETPLWLLSQKRYEDAQKVINIMARWNKVSTPCKVSELCSVQQDDPGTDRTSGNATSSTKKHNILDLFCNWYIARRTITIWLVWFTGSLGYYVFSLSSVNLGGNEYLNLFLIGAVELPCYIIACIGMDKLGRRNTLIPFLILSALICVLIMFIPQDFNVLIILANMAGKFSIGVAFGLIYLYTAELYPTIVRSLAVGSGSMMCRVGSVVAPFCVYLRSVWIFLPLMLEIGLRQFLGICFMI", "length": 527, "header": "tr|A0A8V0YM67-1|A0A8V0YNZ3_CHICK Computationally mapped isoform of Solute carrier family 22 member 16 OS=Gallus gallus OX=9031 GN=DDO PE=3 SV=1 CANONICAL=A0A8V0YNZ3-1" }, "locus": { "chromosome": "3", "start_pos": 66239433, "end_pos": 66212897, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033397.1", "url": "https://www.ensembl.org/id/ENSGALT00010033397.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019702.1", "url": "https://www.ensembl.org/id/ENSGALP00010019702.1" } ] } }, { "isoform_ac": "A0A8V0YNY8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNZ3/entry#A0A8V0YNY8-1", "sequence": { "sequence": "MEYCECLSPPIPTPQMAAPRVAVVGAGLIGLSTALRIAEVNPNCCSITLLSEQFSPNTTSDVAAGMLIPHTYPGTPIHVQKQWFKETFTYLFAISNSAEASEAGIHLVSGWQIFKNPSEAEVPFWSDIVLGFRPMSAAELQKFPQHSHGQAFTTLKCDCPPYLLWLEKRLKANGVQIHTRKVADLWELHSEYDIVVNCTGIGARQLVGDQQLFPIRGQVLKVHAPWVKNFIRDGDGLTYIYPGIDSVTLGGTREKESWRLSPDPGTTKDIFDRCCSLEPSLQRAQDIRVKVGLRPSRSCVRLQREVLSQGGAKLLVVHNYGHGAGGFSVHRGTAEEAAHLVQECIAALQGSSSRAKL", "length": 357, "header": "tr|A0A8V0YNY8-1|A0A8V0YNY8_CHICK Computationally mapped isoform of D-aspartate oxidase OS=Gallus gallus OX=9031 GN=DDO PE=1 SV=1 CANONICAL=A0A8V0YNZ3-1" }, "locus": { "chromosome": "3", "start_pos": 66255518, "end_pos": 66251167, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033392.1", "url": "https://www.ensembl.org/id/ENSGALT00010033392.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019698.1", "url": "https://www.ensembl.org/id/ENSGALP00010019698.1" } ] } }, { "isoform_ac": "A0A8V0YNZ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNZ3/entry#A0A8V0YNZ3-1", "sequence": { "sequence": "MASGSEQLFDSLGHFGRFQACVYFASVFQAMSCGIHYLASVFMAVTPNFVCGIPGNVSSILFYNSSKASLEDIWTMWTSTENYIVAQLENGEIWELNQCSKSKREVSFDLAYEYKGNKSIFSCSDGFLYDVTKWKSTVVTQWDLVCDREWLAKLIQPTFMLGVLVGAVIFGDIADRLGRQRVMWFTSAGQFVFGITVAFTFDYYSFVIVRFLLAMVSSGYLVVAFVYVTEFVGIKARTWASMHVHAFFALGIMVVALVGFLVRTWWVYQIFLSIATLPFVLCCWMLPETPLWLLSQKRYEDAQKVINIMARWNKVSTPCKVSELCSVQQDDPGTDRTSGNATSSTKKHNILDLFCNWYIARRTITIWLVWFTGSLGYYVFSLSSVNLGGNEYLNLFLIGAVELPCYIIACIGMDKLGRRNTLIPFLILSALICVLIMFIPQDFNVLIILANMAGKFSIGVAFGLIYLYTAELYPTIVRSLAVGSGSMMCRVGSVVAPFCVYLRSVWIFLPLRISSCTIILAKLFLLLFITEGKSATKKQSVLEQQRDNCPLWLGSCGLQQHEQPLPAHTPDSFCSVGISQHQTSSPVKIPSEPGKSAVKPKPLLSCSSPFFPSHREVPVSANPHPTDGSPQGGSSGRGAYRTVHSVTYC", "length": 649, "header": "tr|A0A8V0YNZ3-1|A0A8V0YNZ3_CHICK Isoform 1 of Solute carrier family 22 member 16 OS=Gallus gallus OX=9031 GN=DDO PE=3 SV=1 CANONICAL=A0A8V0YNZ3-1" }, "locus": { "chromosome": "3", "start_pos": 66252221, "end_pos": 66212897, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033400.1", "url": "https://www.ensembl.org/id/ENSGALT00010033400.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019703.1", "url": "https://www.ensembl.org/id/ENSGALP00010019703.1" } ] } }, { "isoform_ac": "A0A8V0YTZ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNZ3/entry#A0A8V0YTZ7-1", "sequence": { "sequence": "MAAPRVAVVGAGLIGLSTALRIAEVNPNCCSITLLSEQFSPNTTSDVAAGMLIPHTYPGTPIHVQKQWFKETFTYLFAISNSAEASEAGIHLVSGWQIFKNPSEAEVPFWSDIVLGFRPMSAAELQKFPQHSHGQAFTTLKCDCPPYLLWLEKRLKANGVQIHTRKVADLWELHSEYDIVVNCTGIGARQLVGDQQLFPIRGQVLKVHAPWVKNFIRDGDGLTYIYPGIDSVTLGGTREKESWRLSPDPGTTKDIFDRCCSLEPSLQRAQDIRVKVGLRPSRSCVRLQREVLSQGGAKLLVVHNYGHGAGGFSVHRGTAEEAAHLVQECIAALQGSSSRAKL", "length": 342, "header": "tr|A0A8V0YTZ7-1|A0A8V0YTZ7_CHICK Computationally mapped isoform of D-aspartate oxidase OS=Gallus gallus OX=9031 GN=DDO PE=1 SV=1 CANONICAL=A0A8V0YNZ3-1" }, "locus": { "chromosome": "3", "start_pos": 66255518, "end_pos": 66252154, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033389.1", "url": "https://www.ensembl.org/id/ENSGALT00010033389.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019696.1", "url": "https://www.ensembl.org/id/ENSGALP00010019696.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 626, "start_aa": "Thr", "end_pos": 626, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr626", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:421757", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:421757", "resource": "KEGG Pathway" }, { "id": "gga:770953", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:770953", "resource": "KEGG Pathway" }, { "id": "R-GGA-549127", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-549127", "resource": "Reactome", "description": "SLC-mediated transport of organic cations" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0R4IZE6-1", "protein_name": "D-aspartate oxidase", "gene_name": "ddo", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MKRVKVAVVGAGVVGLSTAVCIAETLPYCSVTLISEKFSPHTTSDGAAGILLPKEFPDIPLEWQQQWFKKSFEYLLAIADSPQASDAGVYLSSGYQIFKDVPRDKKPFWADLVFGFRYMTDHELKRFPDHKFGQAFTTLKCECLSYLPWLEQRFIAVGGRIIHEKVTDLHKLALNYDAIINCSGLGSRALLKDEEVYPVRGQILKLHAPWLKNFIRDGDGNTYIYPGIRFVSVGGTRQADDWRMELDERDREGILERSVRLEPSLRAAAILGEWVGLRPARENLRLEREYVNVGGRAVPLVHNYGHGSCGVTLSWGTALDALHLLRKSLLEKPPQARL", "length": 338 }, "evidence": [ { "id": "A0A8V0YNZ3", "url": "https://omabrowser.org/oma/group/A0A8V0YNZ3/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A3L7I4T7-1", "protein_name": "D-amino-acid oxidase", "gene_name": "Ddo", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MDTVHIAVVGAGVIGLSTAMCISQLVPRSSITVISDKFTPDTTSNVAAGMLIPHKYPDTPVPTLKQWFTETFQHLSEIAKSAEAVDAGVHLVSGWQVFRSVPHEEVPFWADVVLGFRKMTEAELKRFPQHIFGQAFTTLKCETSAYLPWLEKRIKEGGGLLLTRRIEDLWELQPSFDIVVNCSGLGSRQLVGDSTISPVRGQVLRVQAPWVKHFIRDGSGLTYVYPGTSYVTLGGTRQEGDWNLSPDAELSREIFSRCCALEPSLHRAYSIEEKVGLRPSRPDVRLQKELLVQGGQRLLVVHNYGHGSGGISVHWGSALEATRLVMEWIHTLRTPAPMSKM", "length": 341 }, "evidence": [ { "id": "A0A8V0YNZ3", "url": "https://omabrowser.org/oma/group/A0A8V0YNZ3/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A3KCL7-1", "protein_name": "D-aspartate oxidase", "gene_name": "DDO", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDTVRIAVVGAGVMGLSTAVCIFKLVPGCSITVISDKFTPETTSDVAAGMLIPPVYPDTPIHKQKQWFKDTFDHLFAIANSAEAKDAGVLLVSGWQIFQSAPTEEVPFWADVVLGFRKMTKNELKKFPQHVCGQAFTTLKCEGPTYLPWLEKRVKGSGGLVLTRRVEDLWELHPSFNIVVNCSGLGSKQLVGDMEIFPVRGQVLKVQAPWVKHFIRDGSGLTYIYPGIANVTLGGTRQKGDWNLSPNAEISKQILSRCCALEPSLRGACDIREKVGLRPSRPGVRLEKELLVQGSQRLPVVHNYGHGSGGIAMHWGTALEAARLVSECVQALRTPAPKSKL", "length": 341 }, "evidence": [ { "id": "A0A8V0YNZ3", "url": "https://omabrowser.org/oma/group/A0A8V0YNZ3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "D3ZDM7-1", "protein_name": "D-aspartate oxidase", "gene_name": "Ddo", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDTVRIAVVGAGVIGLSTAACVSQLVPRCSVTVISDRFTPDTTSNVAAGMLIPPTYPDTPVPTLKRWFRETFQHLSEIARSAEAVDAGIHLVSGWQIFRSVPTEEVPFWADVVLGFREMTEAELKRFPQYEFGQAFTTLKCETSAYLPWLEKRIKGSGGLLLTRRIEDLWELQPSFDIVVNCSGLGSRRLVGDATVSPVRGQVLQAQAPWVKHFIRDGGGLTYVYPGTSYVTLGGSRQTGDWNLSPDAELSREIFSRCCALEPSLHRACDIKEKVGLRPSRPGVRLQKEILVRGEQRLPVVHNYGHGSGGISVHWGSALEATRLVMECVHTLRTPASLSKL", "length": 341 }, "evidence": [ { "id": "A0A8V0YNZ3", "url": "https://omabrowser.org/oma/group/A0A8V0YNZ3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1RT02-1", "protein_name": "Solute carrier family 22 member 16", "gene_name": "SLC22A16", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEAGNLEVIFDRVGHFGRYQIFLYFMCAFQNISCGIHYLASVFLSVSPQHACRPPGNVSQVLFQDISGVRLEDIWTRFSVGREDRIIVQLQNGEIWELTSCHRFRRDDKSSLNHDYNGHKSSFPCLDGYIYDKSKWRSTVVTEWDLVCNREWFGRLIQPVFMLGVLLGAAVFGYLSDRTGRRVILWTTSIGVFLCGIGVAFTFDYYSFMIARFLLAMVGSGYLVVVFVYVTEFVGMKSRTWASIHLHSFFAFGTMVVALTGYFVRTWWIYQIILSMVTVPFVLCCWMLPETPFWLLSEGRYEEAQKVIDRMAKWNRTRSFKLSELLSLAGSGPAGTKASPVEKHSLSDLFYDCSIGTRTLIVWLIWFTGCFGFYSFSLNSVNLGGNEYLNFFLMGIVEIPAYIFVCVGMDRLGRRCILGFSLLSSAVTNGVIMVIPQDYHVCLMVATMAGKFSIGAAFGLIYLYTAELYPTIVRSLAVGSGSMVSRVGSIMAPFCVYLSSIWIFMPQLLVGTFAFMSGILTFMLPETLRKPLATTWKETEKQSSSDK", "length": 547 }, "evidence": [ { "id": "A0A8V0YNZ3", "url": "https://omabrowser.org/oma/group/A0A8V0YNZ3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P31228-1", "protein_name": "D-aspartate oxidase", "gene_name": "DDO", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MDTVRIAVVGAGVMGLSTAVCISKMVPGCSITVISDKFTPETTSDVAAGMLIPPTYPDTPIQKQKQWFKETFDHLFAIVNSAEAEDAGVILVSGWQIFQSIPTEEVPYWADVVLGFRKMTKDELKKFPQHVFGHAFTTLKCEGPAYLPWLQKRVKGNGGLILTRRIEDLWELHPSFDIVVNCSGLGSRQLAGDSKIFPVRGQVLKVQAPWVKHFIRDSSGLTYIYPGISNVTLGGTRQKGDWNLSPDAEISKEILSRCCALEPSLRGAYDLREKVGLRPTRPGVRLEKELLAQDSRRLPVVHHYGHGSGGIAMHWGTALEATRLVNECVQVLRTPAPKSKL", "length": 341 }, "evidence": [ { "id": "A0A8V0YNZ3", "url": "https://omabrowser.org/oma/group/A0A8V0YNZ3/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q17QN9-1", "protein_name": "Solute carrier family 22 member 16", "gene_name": "SLC22A16", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGSSNLELIFDSVGHFGRYQIFLYFICAFQNISCGIHYLASVFLSVSPQHTCRPPGNVSQVLFQDLSTWQLEDIWTQFSVGREDRILVQLQDGAIWELTSCQRFRRDDQSSLDYEYSGQKSSFPCLDGYIYDRSKWLSTVVTQWDLVCNREWFGRLIQPTFMFGVLLGAVIFGYLSDRAGRRLVLWASSTGVFLFGIAAAFTFDYYSFIVARFLLAISGSGYLVVVFVYVTEFVGMKSRTWASIHLHSFFAFGTMVVALTGYFVRTWWIYQIVLSSVTVPFVLCCWMLPETPFWLISGGKYEEAQKVIDTMAKWNRTRPCKLSEILSLDHDGSAGNKPSQVEKHTLSELFYDWSIGTRTLILWLIWFTGCLGFYTFSLNSVHLGGSEYLNLFLMGVVEIPAYVLVCLGMDRVGRRNILIFSLLSSAVTSGVIMVIPKDYHVWLVVASMAGKFFIGAAFGLIYLYTAELYPTIVRSLAVGSGSTVGRVGSIVAPLCIYLSSVWIFMPQLLVGTLALVSGVLTFLLPETLRRPLTTTWEETEKESSSGKLLSTTSNTVLENVTVENSEDSSLNK", "length": 572 }, "evidence": [ { "id": "A0A8V0YNZ3", "url": "https://omabrowser.org/oma/group/A0A8V0YNZ3/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q497L8-1", "protein_name": "Solute carrier family 22 member 16", "gene_name": "Slc22a16", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MESCNVELIFDHIGHFGRFQIVLYLICAYQSLSCGIHYLSSVFLSIIPEHACKPPGMVRKAVFHNVSAWRLEDILALRSPEHKDHIMVELQDGEIWELTRCSRTWRENTSHLGYEYSGYKHDSPCFDGYVYDQSKWRNSAVRNFNLVCDQKWYARMIQPLIIFGVMLGSITFSYLSDRFGRRMALWCTSIGVFFFGIASLFIFDYLSFMITRFFLVMASSGYFVVVFVYVMEIIGKKARTWASIHLNTFFAIGAMLVALASYLLKTWWLYQIILCIVTTPFILCCWMLPETPFWLLSEGRYKEAQGTVDTMAVWNKSSSCDLVELLSLDVTRSHNKSPHSIRKHRLADLFHNLDVAKMTLIVWLDWFTANLGYYMFGKEVIRRKENEPLYLLLVGAMEIPAYICLCIWLKRVGRRKTMLLFLLVSSLTCMLHVVMPSDYKTAKRMVALLVKSVISSVFAFIYLYTAELYPTTVRCLAVGSSNMVSHVSSIFIPFTSHFSKVWIFLPQILFGILAILSGLLSLKLPETQDTPMKSTWETTEQQVPENKDSLGEGPPDSFERWDSSRALSFAERWGLSRASPDAEKWGSGRVPPDAGKWGAGIAPPVTERGASGRASLEDESGGSGRAPPEKNTEMENEIENMKVSNLGGF", "length": 649 }, "evidence": [ { "id": "A0A8V0YNZ3", "url": "https://omabrowser.org/oma/group/A0A8V0YNZ3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q556W1-1", "protein_name": "D-amino-acid oxidase", "gene_name": "ddo-2", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNQNKNNNNKNPKINLLIIGCGCIGLSTGIIALKSGNYKSVSIWAKDLPPNTTSNKAAALWYPFLCNPLDLVGKWSAETMQYYKDHIINDPKSGTITKKVNEIFRRPHPEDPEWKPYIKSFRRARKDELPDGYVDGYAIDDGFVMDTDMYMDYLVDQFKSLGGIIEQRHLVDIREAFVDHDVVVNCTGLGSRELFNDRTIYPGRGQIIVIKNSTDRSIMDEEDHIAYVIPRLTNTVLGGTNQEHDYNTNPTKKDTEEILKRVAMISPRFAKNRIEIQGVKVGLRPARHEIRLENEFFEGGSKLVVHNYGHGGSGFTVSWGCAIEAIKLVDQGLPKLLHFNKLISKL", "length": 346 }, "evidence": [ { "id": "A0A8V0YNZ3", "url": "https://omabrowser.org/oma/group/A0A8V0YNZ3/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q86VW1-1", "protein_name": "Solute carrier family 22 member 16", "gene_name": "SLC22A16", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGSRHFEGIYDHVGHFGRFQRVLYFICAFQNISCGIHYLASVFMGVTPHHVCRPPGNVSQVVFHNHSNWSLEDTGALLSSGQKDYVTVQLQNGEIWELSRCSRNKRENTSSLGYEYTGSKKEFPCVDGYIYDQNTWKSTAVTQWNLVCDRKWLAMLIQPLFMFGVLLGSVTFGYFSDRLGRRVVLWATSSSMFLFGIAAAFAVDYYTFMAARFFLAMVASGYLVVGFVYVMEFIGMKSRTWASVHLHSFFAVGTLLVALTGYLVRTWWLYQMILSTVTVPFILCCWVLPETPFWLLSEGRYEEAQKIVDIMAKWNRASSCKLSELLSLDLQGPVSNSPTEVQKHNLSYLFYNWSITKRTLTVWLIWFTGSLGFYSFSLNSVNLGGNEYLNLFLLGVVEIPAYTFVCIAMDKVGRRTVLAYSLFCSALACGVVMVIPQKHYILGVVTAMVGKFAIGAAFGLIYLYTAELYPTIVRSLAVGSGSMVCRLASILAPFSVDLSSIWIFIPQLFVGTMALLSGVLTLKLPETLGKRLATTWEEAAKLESENESKSSKLLLTTNNSGLEKTEAITPRDSGLGE", "length": 577 }, "evidence": [ { "id": "A0A8V0YNZ3", "url": "https://omabrowser.org/oma/group/A0A8V0YNZ3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q922Z0-1", "protein_name": "D-aspartate oxidase", "gene_name": "Ddo", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDTVCIAVVGAGVIGLSTAACISQLVPGCTVTVISDRFTPDTTSNVAAGMLIPHTCADTPVPTQKRWFRETFEHLSEIAKSAEAADAGVHLVSGWQIFRSVPAEEVPFWADVVLGFRKMTEAELKRFPQYVFGQAFTTLKCETSAYLPWLERRIKGSGGLLLTRRIEDLWELQPSFDIVVNCSGLGSRRLVGDPMISPVRGQVLQARAPWVKHFIRDGGGLTYVYPGMSYVTLGGTRQKGDWNRSPDAELSREIFSRCCTLEPSLHRAYDIKEKVGLRPSRPGVRLQKEILVRGQQTLPVVHNYGHGSGGISVHWGSALEATRLVMECIHTLRTPASLSKL", "length": 341 }, "evidence": [ { "id": "A0A8V0YNZ3", "url": "https://omabrowser.org/oma/group/A0A8V0YNZ3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q99489-1", "protein_name": "D-aspartate oxidase", "gene_name": "DDO", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDTARIAVVGAGVVGLSTAVCISKLVPRCSVTIISDKFTPDTTSDVAAGMLIPHTYPDTPIHTQKQWFRETFNHLFAIANSAEAGDAGVHLVSGWQIFQSTPTEEVPFWADVVLGFRKMTEAELKKFPQYVFGQAFTTLKCECPAYLPWLEKRIKGSGGWTLTRRIEDLWELHPSFDIVVNCSGLGSRQLAGDSKIFPVRGQVLQVQAPWVEHFIRDGSGLTYIYPGTSHVTLGGTRQKGDWNLSPDAENSREILSRCCALEPSLHGACNIREKVGLRPYRPGVRLQTELLARDGQRLPVVHHYGHGSGGISVHWGTALEAARLVSECVHALRTPIPKSNL", "length": 341 }, "evidence": [ { "id": "A0A8V0YNZ3", "url": "https://omabrowser.org/oma/group/A0A8V0YNZ3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9SA38-1", "protein_name": "Organic cation/carnitine transporter 3", "gene_name": "OCT3", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MADSTRPLLSDFNSSESNLPPPRSLEETIERCIGDFGWAQFLQAALVSFAWFFDAQQTFITVFTDSQPMWHCDNSDRVDSVCNTSSSNLCTLPNQTWSWDLNPHVSIISEWGLQCAGSFLKGFPASSFFLGCLIGGLALSTLADSSLGRKNMLLLSCLIMSLSSMLTAFSTSIWVYAFLRFLNGCGRATIGTCALVLSTELVGKKWRGQVGAMGFFCFTLGFLSLPMLGYINEGNSWRNLYVWTSIPTLIYCCLVRSFVRESPRWLIVKGRKEEAVSILQSIASNAITMSFTNLCFEVENDQSKSNPDVYDALKILVRKSWSFRRLLAAMVVGFGIGMVYYGMPLALTNLNFNLYLGVVFNALSEFPAFLITFFFIDKINRRDALIGFTALSGISSALIAVLGQQLGSLQIVLELVSFFSACTAFNMTLIYTIEMFPTCVRNSAISMVRQALVFGGVFSPVMVAAGRENQFWSYGLFGLIIGLCGLFVFGLPETRGSVLCDTMDEEEYKTLAKRQFIG", "length": 518 }, "evidence": [ { "id": "A0A8V0YNZ3", "url": "https://omabrowser.org/oma/group/A0A8V0YNZ3/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "monoatomic ion transport", "id": "GO:0006811", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006811", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNZ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNZ3" } ], "pmid": "" }, { "name": "D-amino acid catabolic process", "id": "GO:0019478", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019478", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNZ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNZ3" } ], "pmid": "" }, { "name": "acid secretion", "id": "GO:0046717", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046717", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNZ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNZ3" } ], "pmid": "" }, { "name": "organic cation transport", "id": "GO:0015695", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015695", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNZ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNZ3" } ], "pmid": "" }, { "name": "flagellated sperm motility", "id": "GO:0030317", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030317", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNZ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNZ3" } ], "pmid": "" }, { "name": "single fertilization", "id": "GO:0007338", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007338", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNZ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNZ3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNZ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNZ3" } ], "pmid": "" }, { "name": "peroxisomal matrix", "id": "GO:0005782", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005782", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNZ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNZ3" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNZ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNZ3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 6, "go_terms": [ { "name": "transmembrane transporter activity", "id": "GO:0022857", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022857", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNZ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNZ3" } ], "pmid": "" }, { "name": "D-aspartate oxidase activity", "id": "GO:0008445", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008445", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNZ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNZ3" } ], "pmid": "" }, { "name": "FAD binding", "id": "GO:0071949", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071949", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNZ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNZ3" } ], "pmid": "" }, { "name": "amine transmembrane transporter activity", "id": "GO:0005275", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005275", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNZ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNZ3" } ], "pmid": "" }, { "name": "carnitine transmembrane transporter activity", "id": "GO:0015226", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015226", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNZ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNZ3" } ], "pmid": "" }, { "name": "spermidine transmembrane transporter activity", "id": "GO:0015606", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015606", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNZ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNZ3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 117, "end_pos": 119, "annotation": "n_glycosylation_sequon" }, { "start_pos": 340, "end_pos": 342, "annotation": "n_glycosylation_sequon" }, { "start_pos": 56, "end_pos": 58, "annotation": "n_glycosylation_sequon" }, { "start_pos": 64, "end_pos": 66, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "10028", "name": "", "equation": "D-glutamate + O2 + H2O = 2-oxoglutarate + H2O2 + NH4(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YNZ3-1" ], "evidence": [ { "id": "10028", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/10028" } ] }, { "id": "12512", "name": "", "equation": "D-aspartate + O2 + H2O = oxaloacetate + H2O2 + NH4(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YNZ3-1" ], "evidence": [ { "id": "12512", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/12512" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A8V0YNZ3", "gene_name": "DDO", "activity": [ { "ec_number": "1.4.3.1", "activity": "D-aspartate + O2 + H2O = 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NH4(+).", "evidence": [ { "id": "1.4.3.1", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:1.4.3.1" }, { "id": "1.4.3.1", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=1.4.3.1" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 626 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 117, "end_pos": 119 }, { "start_pos": 340, "end_pos": 342 }, { "start_pos": 56, "end_pos": 58 }, { "start_pos": 64, "end_pos": 66 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { 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"count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YPH5-1", "uniprot_ac": "A0A8V0YPH5", "uniprot_id": "A0A8V0YPH5_CHICK", "mass": { "chemical_mass": 113387.0, "monoisotopic_mass": 113387.0 }, "refseq": {}, "gene_names": [ { "name": "AHR1B", "type": "recommended", "evidence": [ { "id": "A0A8V0YPH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPH5" } ] } ], "protein_names": [ { "name": "Aryl hydrocarbon receptor 1 beta", "type": "synonym", "evidence": [ { "id": "A0A8V0YPH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPH5/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPH5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPH5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "AHR1B", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPH5", "locus": { "chromosome": "7", "start_pos": 6670257, "end_pos": 6656032, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010014105", "url": "https://www.ensembl.org/id/ENSGALG00010014105" } ] } } ], "crossref": [ { "id": "A0A8V0YPH5", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YPH5", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00130", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00130", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100859347", "url": "https://www.ncbi.nlm.nih.gov/gene/100859347", "database": "GeneID", "categories": [ "Genome 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"InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039091", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039091", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:100859347", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100859347", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "ISQHQGC", "url": "https://omabrowser.org/oma/group/ISQHQGC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YMQ9", "url": "https://www.orthodb.org/?gene=A0A8V0YMQ9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YPH5", "url": "https://www.orthodb.org/?gene=A0A8V0YPH5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10649", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10649", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10649:SF18", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10649:SF18", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00989", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00989", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08447", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08447", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YMQ9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMQ9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YMQ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMQ9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YPH5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPH5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YPH5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPH5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MYAGRKRRKPAARALHAADSGRSNPSKRHRERLNRELERLAALLPFPEEVAAGLDKLSILRLSAAFLRAKSFFRVALKNHGAEGAERGGDHDSRPALGTAAVPEGELLLQALNGFVLVVTSEGLIFYSSHTIQDYLGFHQTDVMHQSIFKLIHTEDHQEFRRNLHWALNPPHTPEGEPSPEGMKSLSSPAVAYRPDQLPLENSSFLERSFVCRFRCLLDNSSGFLALNLQGRLRFLHGQNKRSEDGSALPPQLALFAISTPLQPPSILEIRTKNMIFRTKHKLDFTPLACDAKGKIVLGYTEAELRMCGTGYQFIHAADMLYCAENHIRMMKTGESGLTVFRLLTKDKHWKWVQANARLVYKNSKPEYIIVTQRPLVDEEGGEHLRKRSMHLPFTFATGEAVLYQSAFPLPGFCDAFQRKGKISKSKKTSHSNGGCFQKDSIAPGSLLSAVLQQDKAAYAPHPAPSPNHTFSSSFLDHLEDTSSLGTGRAWSTSTAPVSSRKDGLKEEWVDLQQEDPLLATLNSLTINGDESCSNSELFSALESLGLNAEDLELLLLDEKMVMVNTDPDHTLSLSDFLTNNEIISYIHTMLGNKYKEGLQVCPLPGTVSCPVGGSAAYQAHAEDKDSQYPSQQIQQPGIVPGQAAALLWEHPLHNALAQLSPLPSKLAEAEEELPAGLQSRPGGEEGLLRFLQLTQVTPWAVAPGSHLGAPCPLEAQQLESDFPAVHPTQEDVLQTSSLSIQGRGRGAAPSQPKHKAGRCLLMDRLCAHHHPSATRLLPTSSNSPWQDYVSPLLTSSAQPDFYGISQDLISQHQGYLGPVPGPAVPAVDSNLNGLCSMDTIDSERSQEEMVPYSGLFPSSSYQFIPEMHPSSIPAMYPFLSSSAEHFGSTDSVLEDPANSYGVYTSMMSQESSHKVWCHDHCPHAEQEPVIYSYAEQEPVIYSLTAAVFCLALTWDSVQMCQRAALLPPASCIAMQKCCRITPTLSAVTSISRGTRLDWAKWDYSLGKELPSSCRQQIFPLPRVSCLCSW", "length": 1030, "header": "tr|A0A8V0YPH5-1|A0A8V0YPH5_CHICK Isoform 1 of Aryl hydrocarbon receptor 1 beta OS=Gallus gallus OX=9031 GN=AHR1B PE=4 SV=1 CANONICAL=A0A8V0YPH5-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YMQ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPH5/entry#A0A8V0YMQ9-1", "sequence": { "sequence": 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"tr|A0A8V0YMQ9-1|A0A8V0YPH5_CHICK Computationally mapped isoform of Aryl hydrocarbon receptor 1 beta OS=Gallus gallus OX=9031 GN=AHR1B PE=4 SV=1 CANONICAL=A0A8V0YPH5-1" }, "locus": { "chromosome": "7", "start_pos": 6669022, "end_pos": 6656121, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033866.1", "url": "https://www.ensembl.org/id/ENSGALT00010033866.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019916.1", "url": "https://www.ensembl.org/id/ENSGALP00010019916.1" } ] } }, { "isoform_ac": "A0A8V0YPH5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPH5/entry#A0A8V0YPH5-1", "sequence": { "sequence": "MYAGRKRRKPAARALHAADSGRSNPSKRHRERLNRELERLAALLPFPEEVAAGLDKLSILRLSAAFLRAKSFFRVALKNHGAEGAERGGDHDSRPALGTAAVPEGELLLQALNGFVLVVTSEGLIFYSSHTIQDYLGFHQTDVMHQSIFKLIHTEDHQEFRRNLHWALNPPHTPEGEPSPEGMKSLSSPAVAYRPDQLPLENSSFLERSFVCRFRCLLDNSSGFLALNLQGRLRFLHGQNKRSEDGSALPPQLALFAISTPLQPPSILEIRTKNMIFRTKHKLDFTPLACDAKGKIVLGYTEAELRMCGTGYQFIHAADMLYCAENHIRMMKTGESGLTVFRLLTKDKHWKWVQANARLVYKNSKPEYIIVTQRPLVDEEGGEHLRKRSMHLPFTFATGEAVLYQSAFPLPGFCDAFQRKGKISKSKKTSHSNGGCFQKDSIAPGSLLSAVLQQDKAAYAPHPAPSPNHTFSSSFLDHLEDTSSLGTGRAWSTSTAPVSSRKDGLKEEWVDLQQEDPLLATLNSLTINGDESCSNSELFSALESLGLNAEDLELLLLDEKMVMVNTDPDHTLSLSDFLTNNEIISYIHTMLGNKYKEGLQVCPLPGTVSCPVGGSAAYQAHAEDKDSQYPSQQIQQPGIVPGQAAALLWEHPLHNALAQLSPLPSKLAEAEEELPAGLQSRPGGEEGLLRFLQLTQVTPWAVAPGSHLGAPCPLEAQQLESDFPAVHPTQEDVLQTSSLSIQGRGRGAAPSQPKHKAGRCLLMDRLCAHHHPSATRLLPTSSNSPWQDYVSPLLTSSAQPDFYGISQDLISQHQGYLGPVPGPAVPAVDSNLNGLCSMDTIDSERSQEEMVPYSGLFPSSSYQFIPEMHPSSIPAMYPFLSSSAEHFGSTDSVLEDPANSYGVYTSMMSQESSHKVWCHDHCPHAEQEPVIYSYAEQEPVIYSLTAAVFCLALTWDSVQMCQRAALLPPASCIAMQKCCRITPTLSAVTSISRGTRLDWAKWDYSLGKELPSSCRQQIFPLPRVSCLCSW", "length": 1030, "header": "tr|A0A8V0YPH5-1|A0A8V0YPH5_CHICK Isoform 1 of Aryl hydrocarbon receptor 1 beta OS=Gallus gallus OX=9031 GN=AHR1B PE=4 SV=1 CANONICAL=A0A8V0YPH5-1" }, "locus": { "chromosome": "7", "start_pos": 6669137, "end_pos": 6656121, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033860.1", "url": "https://www.ensembl.org/id/ENSGALT00010033860.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019912.1", "url": "https://www.ensembl.org/id/ENSGALP00010019912.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:100859347", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100859347", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPH5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPH5" } ], "pmid": "" }, { "name": "protein dimerization activity", "id": "GO:0046983", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046983", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPH5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPH5" } ], "pmid": "" }, { "name": "transcription cis-regulatory region binding", "id": "GO:0000976", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000976", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPH5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPH5" } ], "pmid": "" }, { "name": "nuclear receptor activity", "id": "GO:0004879", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004879", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPH5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPH5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPH5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPH5" } ], "pmid": "" }, { "name": "aryl hydrocarbon receptor complex", "id": "GO:0034751", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034751", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPH5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPH5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPH5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPH5" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPH5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPH5" } ], "pmid": "" }, { "name": "xenobiotic metabolic process", "id": "GO:0006805", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006805", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPH5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPH5" } ], "pmid": "" }, { "name": "intracellular receptor signaling pathway", "id": "GO:0030522", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030522", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPH5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPH5" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPH5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPH5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 202, "end_pos": 204, "annotation": "n_glycosylation_sequon" }, { "start_pos": 220, "end_pos": 222, "annotation": 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"total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YMU1-1", "uniprot_ac": "A0A8V0YMU1", "uniprot_id": "A0A8V0YMU1_CHICK", "mass": { "chemical_mass": 27038.0, "monoisotopic_mass": 27038.0 }, "refseq": {}, "gene_names": [ { "name": "LOC430910", "type": "recommended", "evidence": [ { "id": "A0A8V0YMU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMU1" } ] } ], "protein_names": [ { "name": "Transcription factor BTF3", "type": "recommended", "evidence": [ { "id": "A0A8V0YMU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMU1/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMU1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMU1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LOC430910", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMU1", "locus": {} } ], "crossref": [ { "id": "A0A8V0YMU1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YMU1", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd22055", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22055", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR002715", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002715", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038187", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038187", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039370", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039370", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YMU1", "url": "https://www.orthodb.org/?gene=A0A8V0YMU1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YMU9", "url": "https://www.orthodb.org/?gene=A0A8V0YMU9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10351", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10351", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01849", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01849", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YMU1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMU1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YMU1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMU1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YMU9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMU9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YMU9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMU9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKETIMNQEKLAKLQAEVRIGGKGTARRKKKVVHRTATADEKKLQFSLKKLGVNNISGIEESYRMAWVEKDLKDHLVSTPLPRARSPTTRLSCPELHPALPCFHGWGIHNLFRNFSYFPIKLRKHGKLLELLDYLFIYLQVNMFTNQGTVIHFNNPKVQASLAANTFTITGHAETKQLTEMLPSILNQLGADSFSSLRRLAEALPKQSVNEKAPLATGDDDDEVPDLVENFDEASKNEGN", "length": 240, "header": "tr|A0A8V0YMU1-1|A0A8V0YMU1_CHICK Isoform 1 of Transcription factor BTF3 OS=Gallus 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"o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YMX5-1", "uniprot_ac": "A0A8V0YMX5", "uniprot_id": "A0A8V0YMX5_CHICK", "mass": { "chemical_mass": 36734.0, "monoisotopic_mass": 36734.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "NK1 transcription factor-related protein 1", "type": "recommended", "evidence": [ { "id": "A0A8V0YMX5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMX5/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMX5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMX5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMX5", "locus": {} } ], "crossref": [ { "id": "A0A8V0YMX5", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YMX5", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00086", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00086", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001356", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001356", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009057", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009057", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017970", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017970", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020479", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020479", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050394", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050394", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR24340", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24340", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24340:SF26", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24340:SF26", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00046", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00046", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YMX5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMX5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YMX5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMX5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "RSSRAEAPSRASPRDSVPPLEASNTPGQEGAVAALPIVHRTTSFSVLDILDPNKFNSKRRQCAVFGEPGALGSRGCANAACRAAGRCNCVLGRGTARRGPGAALCYGQSFPCAAPLPAFPIAELVVRGPTAAPGPLSPEQRRGTPAGQGALHGAAAGTGEEAASPPGPTRERLPQPPPPQQPGGGQQQAKPKRKRTGSDSKSGKPRRARTAFTYEQLVALENKFKSTRYLSVCERLNLALSLSLTETQVKIWFQNRRTKWKKQNPGADTSAPTGGGGAGGGAGGALGGGALPGGLSPLSHSPPMGNPLSMHGPGSYAGHPAGGLVCAAQLPFLPSPAVLSPFVLGSQTYGAPAFYTPHL", "length": 359, "header": "tr|A0A8V0YMX5-1|A0A8V0YMX5_CHICK Isoform 1 of NK1 transcription factor-related protein 1 OS=Gallus gallus OX=9031 GN= PE=3 SV=1 CANONICAL=A0A8V0YMX5-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YMX5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMX5/entry#A0A8V0YMX5-1", "sequence": { "sequence": "RSSRAEAPSRASPRDSVPPLEASNTPGQEGAVAALPIVHRTTSFSVLDILDPNKFNSKRRQCAVFGEPGALGSRGCANAACRAAGRCNCVLGRGTARRGPGAALCYGQSFPCAAPLPAFPIAELVVRGPTAAPGPLSPEQRRGTPAGQGALHGAAAGTGEEAASPPGPTRERLPQPPPPQQPGGGQQQAKPKRKRTGSDSKSGKPRRARTAFTYEQLVALENKFKSTRYLSVCERLNLALSLSLTETQVKIWFQNRRTKWKKQNPGADTSAPTGGGGAGGGAGGALGGGALPGGLSPLSHSPPMGNPLSMHGPGSYAGHPAGGLVCAAQLPFLPSPAVLSPFVLGSQTYGAPAFYTPHL", "length": 359, "header": "tr|A0A8V0YMX5-1|A0A8V0YMX5_CHICK Isoform 1 of NK1 transcription factor-related protein 1 OS=Gallus gallus OX=9031 GN= PE=3 SV=1 CANONICAL=A0A8V0YMX5-1" }, "locus": { "chromosome": "4", "start_pos": 83932584, "end_pos": 83927492, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010038599.1", "url": "https://www.ensembl.org/id/ENSGALT00010038599.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010022335.1", "url": "https://www.ensembl.org/id/ENSGALP00010022335.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 130, "start_aa": "Thr", "end_pos": 130, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr130", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 169, "start_aa": "Thr", "end_pos": 169, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr169", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMX5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMX5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMX5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMX5" } ], "pmid": "" }, { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMX5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMX5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMX5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMX5" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMX5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMX5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YMX5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMX5" }, { "id": "PS50071", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50071" }, { "id": "PRU00108", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00108" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Homeobox", "eco_id": "ECO_0000259", "start_pos": 203, "end_pos": 263, "start_aa": "Gly", "end_aa": "Gln", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 130, 169 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YMZ5-1", "uniprot_ac": "A0A8V0YMZ5", "uniprot_id": "A0A8V0YMZ5_CHICK", "mass": { "chemical_mass": 25891.0, "monoisotopic_mass": 25891.0 }, "refseq": { "ac": "NP_001239207", "name": "synaptogyrin-1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001239207" }, "gene_names": [ { "name": "SYNGR1", "type": "recommended", "evidence": [ { "id": "A0A8V0YMZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMZ5" } ] }, { "name": "SYNGR1", "type": "synonym", "evidence": [ { "id": "NP_001239207", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001239207" } ] } ], "protein_names": [ { "name": "Synaptogyrin", "type": "recommended", "evidence": [ { "id": "A0A8V0YMZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMZ5/entry#names_and_taxonomy" } ] }, { "name": "synaptogyrin-1", "type": "synonym", "evidence": [ { "id": "NP_001239207", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001239207" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: SRR12888541.104443.1, SRR12888498.149930.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992437, SAMEA103992533 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000012.1. On Sep 23, 2021 this sequence version replaced NP_001239207.3. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001239207", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001239207" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMZ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMZ5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SYNGR1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMZ5", "locus": { "chromosome": "1", "start_pos": 50713266, "end_pos": 50726987, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012565", "url": "https://www.ensembl.org/id/ENSGALG00010012565" } ] } } ], "crossref": [ { "id": "A0A8V0YMZ5", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YMZ5", "database": "AlphaFoldDB", "categories": [] }, { "id": "418015", "url": "https://www.ncbi.nlm.nih.gov/gene/418015", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR008253", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008253", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016579", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016579", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:418015", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418015", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "FYLWSQW", "url": "https://omabrowser.org/oma/group/FYLWSQW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YMZ5", "url": "https://www.orthodb.org/?gene=A0A8V0YMZ5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10838", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10838", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10838:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10838:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01284", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01284", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-6798695", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6798695", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001239207", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001239207", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YMZ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMZ5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YMZ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMZ5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDGGAFGAGKAGGAFDLQAFLRQPHTLLRLLSWVFSIVVFGSIVNEGYVNRLDESEEHCIFNRNRNACNYGITVGVLAFLSCLLYLALDAYFPQISSVKDRKKAVLSDIGVSAFWAFLWFVGFCFLTNQWQASKEEDNPMNEGGDAARAAITFSFFSIFTWVGQAFLAYQRFLLGADSALFSQDYMDPSQDSGMPYAPYTNEEDATDTVGTYQQPPAADAFDTETQGYQTQNY", "length": 233, "header": "tr|A0A8V0YMZ5-1|A0A8V0YMZ5_CHICK Isoform 1 of Synaptogyrin OS=Gallus gallus OX=9031 GN=SYNGR1 PE=3 SV=1 CANONICAL=A0A8V0YMZ5-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YMZ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMZ5/entry#A0A8V0YMZ5-1", "sequence": { "sequence": "MDGGAFGAGKAGGAFDLQAFLRQPHTLLRLLSWVFSIVVFGSIVNEGYVNRLDESEEHCIFNRNRNACNYGITVGVLAFLSCLLYLALDAYFPQISSVKDRKKAVLSDIGVSAFWAFLWFVGFCFLTNQWQASKEEDNPMNEGGDAARAAITFSFFSIFTWVGQAFLAYQRFLLGADSALFSQDYMDPSQDSGMPYAPYTNEEDATDTVGTYQQPPAADAFDTETQGYQTQNY", "length": 233, "header": "tr|A0A8V0YMZ5-1|A0A8V0YMZ5_CHICK Isoform 1 of Synaptogyrin OS=Gallus gallus OX=9031 GN=SYNGR1 PE=3 SV=1 CANONICAL=A0A8V0YMZ5-1" }, "locus": { "chromosome": "1", "start_pos": 50726888, "end_pos": 50716797, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030112.1", "url": "https://www.ensembl.org/id/ENSGALT00010030112.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017493.1", "url": "https://www.ensembl.org/id/ENSGALP00010017493.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:418015", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418015", "resource": "KEGG Pathway" }, { "id": "R-GGA-6798695", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6798695", "resource": "Reactome", "description": "Neutrophil degranulation" } ], "orthologs": [ { "uniprot_canonical_ac": "I3LLM8-1", "protein_name": "Synaptogyrin", "gene_name": "SYNGR1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEGGAYGAGKAGGAFDPYTLVRQPHTILRVVSWVFSIVVFGSIVNEGYLNSPSESEEFCVYNRNPNACGYGVTVGVLAFLTCLLYLALDVYFPQISSVKDRKKAVLSDIGVSAFWAFLWFVGFCYLANQWQVSKPKDNPLNEGTDAARAAIAFSFFSIFTWAGQAVLAFQRYQIGADSALFSQDYMDPSQDSSMPYAPYVEPSTGPDPAGMGGTYQQPANTFDTEPQGYQSQGY", "length": 234 }, "evidence": [ { "id": "A0A8V0YMZ5", "url": "https://omabrowser.org/oma/group/A0A8V0YMZ5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "O55100-1", "protein_name": "Synaptogyrin-1", "gene_name": "Syngr1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEGGAYGAGKAGGAFDPYTLVRQPHTILRVVSWVFSIVVFGSIVNEGYLNNPEEEEEFCIYNRNPNACSYGVTVGVLAFLTCLLYLALDVYFPQISSVKDRKKAVLSDIGVSAFWAFFWFVGFCFLANQWQVSKPKDNPLNEGTDAARAAIAFSFFSIFTWAGQAVLAFQRYQIGADSALFSQDYMDPSQDSSMPYAPYVEPSAGSDPAGMGGTYQHPANAFDAEPQGYQSQGY", "length": 234 }, "evidence": [ { "id": "A0A8V0YMZ5", "url": "https://omabrowser.org/oma/group/A0A8V0YMZ5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q62876-1", "protein_name": "Synaptogyrin-1", "gene_name": "Syngr1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEGGAYGAGKAGGAFDPYTLVRQPHTILRVVSWVFSIVVFGSIVNEGYLNNPEEEEEFCIYNRNPNACSYGVTVGVLAFLTCLVYLALDVYFPQISSVKDRKKAVLSDIGVSAFWAFFWFVGFCFLANQWQVSKPKDNPLNEGTDAARAAIAFSFFSIFTWAGQAVLAFQRYQIGADSALFSQDYMDPSQDSSMPYAPYVEPSAGSDPTGMGGTYQHPANAFDAEPQGYQSQGY", "length": 234 }, "evidence": [ { "id": "A0A8V0YMZ5", "url": "https://omabrowser.org/oma/group/A0A8V0YMZ5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q7JYV2-1", "protein_name": "Synaptogyrin", "gene_name": "Syngr", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MDMLNQILSINNGGAYGGGKAGGAFDPLTFAMKPQVVIRALCWLFSVVVFGCISSEGWTEKDGKEYCLYNGDGMACKYGNMVGVFGFLASMGFMGGEFLFERMSSVKSRKRYVMADMGFSALWTFMYFVAFLYLWSQWSSSAPPPLGIGAGSMKTAIWFCLFSIVSWALCALMAYKRFLIGAGDEFTSAFETDPANVVHQQAYGYSMDNDNDQYSASPFGQPQQGGMEQQQSGMEYQQPTY", "length": 241 }, "evidence": [ { "id": "A0A8V0YMZ5", "url": "https://omabrowser.org/oma/group/A0A8V0YMZ5/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "regulation of short-term neuronal synaptic plasticity", "id": "GO:0048172", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048172", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMZ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMZ5" } ], "pmid": "" }, { "name": "regulation of long-term neuronal synaptic plasticity", "id": "GO:0048169", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048169", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMZ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMZ5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMZ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMZ5" } ], "pmid": "" }, { "name": "neuromuscular junction", "id": "GO:0031594", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031594", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMZ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMZ5" } ], "pmid": "" }, { "name": "synaptic vesicle membrane", "id": "GO:0030672", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030672", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMZ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMZ5" } ], "pmid": "" }, { "name": "Schaffer collateral - CA1 synapse", "id": "GO:0098685", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098685", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMZ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMZ5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YMZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMZ5" }, { "id": "PS51225", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51225" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "MARVEL", "eco_id": "ECO_0000259", "start_pos": 20, "end_pos": 173, "start_aa": "Phe", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YMZ9-1", "uniprot_ac": "A0A8V0YMZ9", "uniprot_id": "A0A8V0YMZ9_CHICK", "mass": { "chemical_mass": 27660.0, "monoisotopic_mass": 27660.0 }, "refseq": {}, "gene_names": [ { "name": "C6orf203", "type": "recommended", "evidence": [ { "id": "A0A8V0YMZ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMZ9" } ] } ], "protein_names": [ { "name": "C6orf203 homolog", "type": "synonym", "evidence": [ { "id": "A0A8V0YMZ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMZ9/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMZ9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMZ9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "C6orf203", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMZ9", "locus": { "chromosome": "3", "start_pos": 67690060, "end_pos": 67696905, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012569", "url": "https://www.ensembl.org/id/ENSGALG00010012569" } ] } } ], "crossref": [ { "id": "A0A8V0YMZ9", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YMZ9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000015316", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000015316", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "421779", "url": "https://www.ncbi.nlm.nih.gov/gene/421779", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR057896", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057896", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:421779", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:421779", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DIGRNQA", "url": "https://omabrowser.org/oma/group/DIGRNQA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YMZ9", "url": "https://www.orthodb.org/?gene=A0A8V0YMZ9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NMS1", "url": "https://www.orthodb.org/?gene=F1NMS1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13633", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13633", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13633:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13633:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF25818", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25818", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YMZ9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMZ9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YMZ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMZ9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NMS1", "url": "https://www.uniprot.org/uniprotkb/F1NMS1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NMS1-1", "url": "https://www.uniprot.org/uniprotkb/F1NMS1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDPDDNLGWTMTGFRLPVTVFRRLNVWVGLWEKFPSNQLFPSWRRSIFCSCQASTINDRRWFSFSPVKLCALRLSPDYISVLSLRNKSSKSSKRNRQTVQEEEEEEEADEQESDLEDEFENDPNVVKDYKDLEKVVQSLRYDVVMKAGLDIARNKVEDAFYNNELRLNGEKLWKKSRTVKIGDTLDLLVGEDKETGTAVVMRVVLKKVSNKTESEKYRVILRRWKNLKVPKQDVLK", "length": 236, "header": "tr|A0A8V0YMZ9-1|A0A8V0YMZ9_CHICK Isoform 1 of C6orf203 homolog OS=Gallus gallus OX=9031 GN=C6orf203 PE=1 SV=1 CANONICAL=A0A8V0YMZ9-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YMZ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMZ9/entry#A0A8V0YMZ9-1", "sequence": { "sequence": "MDPDDNLGWTMTGFRLPVTVFRRLNVWVGLWEKFPSNQLFPSWRRSIFCSCQASTINDRRWFSFSPVKLCALRLSPDYISVLSLRNKSSKSSKRNRQTVQEEEEEEEADEQESDLEDEFENDPNVVKDYKDLEKVVQSLRYDVVMKAGLDIARNKVEDAFYNNELRLNGEKLWKKSRTVKIGDTLDLLVGEDKETGTAVVMRVVLKKVSNKTESEKYRVILRRWKNLKVPKQDVLK", "length": 236, "header": "tr|A0A8V0YMZ9-1|A0A8V0YMZ9_CHICK Isoform 1 of C6orf203 homolog OS=Gallus gallus OX=9031 GN=C6orf203 PE=1 SV=1 CANONICAL=A0A8V0YMZ9-1" }, "locus": { "chromosome": "3", "start_pos": 67696755, "end_pos": 67690558, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030125.1", "url": "https://www.ensembl.org/id/ENSGALT00010030125.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017498.1", "url": "https://www.ensembl.org/id/ENSGALP00010017498.1" } ] } }, { "isoform_ac": "F1NMS1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMZ9/entry#F1NMS1-1", "sequence": { "sequence": "MTGFRLPVTVFRRLNVWVGLWEKFPSNQLFPSWRRSIFCSCQASTINDRRWFSFSPVKLCALRLSPDYISVLSLRNKSSKSSKRNRQTVQEEEEEEEADEQESDLEDEFENDPNVVKDYKDLEKVVQSLRYDVVMKAGLDIARNKVEDAFYNNELRLNGEKLWKKSRTVKIGDTLDLLVGEDKETGTAVVMRVVLKKVSNKTESEKYRVILRRWKNLKVPKQDVLK", "length": 226, "header": "tr|F1NMS1-1|F1NMS1_CHICK Computationally mapped isoform of C6orf203 homolog OS=Gallus gallus OX=9031 GN=C6orf203 PE=1 SV=2 CANONICAL=A0A8V0YMZ9-1" }, "locus": { "chromosome": "3", "start_pos": 67693002, "end_pos": 67690558, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030116.1", "url": "https://www.ensembl.org/id/ENSGALT00010030116.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017494.1", "url": "https://www.ensembl.org/id/ENSGALP00010017494.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:421779", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:421779", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMZ9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMZ9" } ], "pmid": "" }, { "name": "tRNA binding", "id": "GO:0000049", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000049", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMZ9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMZ9" } ], "pmid": "" }, { "name": "ribosomal large subunit binding", "id": "GO:0043023", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043023", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMZ9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMZ9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMZ9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMZ9" } ], "pmid": "" }, { "name": "mitochondrial matrix", "id": "GO:0005759", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005759", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMZ9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMZ9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "regulation of mitochondrial transcription", "id": "GO:1903108", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903108", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YMZ9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMZ9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 210, "end_pos": 212, "annotation": "n_glycosylation_sequon" }, { "start_pos": 86, "end_pos": 88, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YMZ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMZ9" }, { "id": "PF25818", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25818" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Mitochondrial transcription rescue factor 1 C-terminal", "eco_id": "ECO_0000259", "start_pos": 130, "end_pos": 231, "start_aa": "Lys", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 210, "end_pos": 212 }, { "start_pos": 86, "end_pos": 88 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YN05-1", "uniprot_ac": "A0A8V0YN05", "uniprot_id": "A0A8V0YN05_CHICK", "mass": { "chemical_mass": 106370.0, "monoisotopic_mass": 106370.0 }, "refseq": { "ac": "XP_015133879", "name": "dystrophin-related protein 2 isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015133879" }, "gene_names": [ { "name": "DRP2", "type": "recommended", "evidence": [ { "id": "A0A8V0YN05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN05" } ] }, { "name": "DRP2", "type": "synonym", "evidence": [ { "id": "XP_015133879", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015133879" } ] } ], "protein_names": [ { "name": "Dystrophin related protein 2", "type": "synonym", "evidence": [ { "id": "A0A8V0YN05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN05/entry#names_and_taxonomy" } ] }, { "name": "dystrophin-related protein 2 isoform X3", "type": "synonym", "evidence": [ { "id": "XP_015133879", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015133879" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052535.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015133879", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015133879" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YN05", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN05" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "DRP2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN05", "locus": { "chromosome": "4", "start_pos": 2012112, "end_pos": 2030393, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010016053", "url": "https://www.ensembl.org/id/ENSGALG00010016053" } ] } } ], "crossref": [ { "id": "A0A8V0YN05", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YN05", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00176", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00176", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd00201", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00201", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd02334", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02334", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd16248", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16248", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "422193", "url": "https://www.ncbi.nlm.nih.gov/gene/422193", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000433", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000433", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001202", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001202", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002017", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002017", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011992", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011992", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015153", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015153", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015154", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015154", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018159", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018159", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036020", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036020", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043145", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043145", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050774", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050774", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YN00", "url": "https://www.orthodb.org/?gene=A0A8V0YN00", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YN05", "url": "https://www.orthodb.org/?gene=A0A8V0YN05", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12268", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12268", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12268:SF16", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12268:SF16", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00397", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00397", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00435", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00435", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00569", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00569", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF09068", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09068", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF09069", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09069", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-9913351", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9913351", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_015133879", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015133879", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YN00", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN00", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YN00-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN00-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YN05", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN05", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YN05-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN05-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQPLVMQEWPFVVPRCPEWRVAEQARRASAAHPLSQVKGSQDGTGPSCVTPRAAGSAAGPQAPLEMNLCWNEIKKKSHSLRARLEAFSDHSGKLQVPLQEIIDWLGQKDEELSAQLPLRGDVLLVQQEKETHAAFMEEVKSRGPYIYSVLESAQAFLSQHPFEELEEPTSESKDASPRHRIQNISRFVWKQANVASELWEKLTARCVDQHRHIERTLEQLLEIKGAMEELSTALDQAESVRETWEPIGDLFIDSLPEHIQSTKLFKEELSPMKDGVKVVNDLAHQLAISDVHLSMENSRSLEQINTRWKQLQASINERLKQLQDAHRDFGPGSQHFLSSSVQVPWERAISPNKVPYYINHQAQTTCWDHPKMTELYQTLADLNNIKFSAYRTAMKLRRVQKALRLDMVTLATALEIFNEHDLQPSDRAMDVVEVIHCLTSLYERLEEERGILVNVPLCVDMSLNWLLNVFDSGRSGKMRALSFKTGIACLCGTEVKEKFQYLFSQVANAGGLCDQRHLGVLLHEAIQVPRQLGEVAAFGGSNVEPSIRSCFRFSHGKPAIEAAQFLEWANLEPQSMVWLAVLHRVTMAEQVKHQTKCSVCRQCPIKGFRYRSLKQFNVDICQTCFLTGRASKGNKLHYPIMEYYTPTTSSENMRDFATTLKNKFRSKQYFSKHPQRGYLPVQSVLEADFSETPASSPMLPHADTHSRIEHFASRLAEMENQNCSFFSDSLSPDDSLDEDQYLLRHSSPITDREPAGSQQVPGSLPMDDKGELERILAHLEDENRILQGELRRLKWQHDEAVESPTLATGSPESVQDPRNEELLAEARILRQHKSRLETRMQILEDHNKQLESQLHRLRELLLQPPAESNGNGSAASSLASSPHQSEGGQPRDKEHDTPDTEAAADEVEAKTQEVSVCLEDIMEKLRSAFPNSRGMTSLI", "length": 939, "header": "tr|A0A8V0YN05-1|A0A8V0YN05_CHICK Isoform 1 of Dystrophin related protein 2 OS=Gallus gallus OX=9031 GN=DRP2 PE=4 SV=1 CANONICAL=A0A8V0YN05-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YN00-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN05/entry#A0A8V0YN00-1", "sequence": { "sequence": "MQPLVMQEWPFVVPRCPEWRVAEQARRASAAHPLSQVKGSQDGTGPSCVTPRAAGSAAGPQAPLEMNLCWNEIKKKSHSLRARLEAFSDHSGKLQVPLQEIIDWLGQKDEELSAQLPLRGDVLLVQQEKETHAAFMEEVKSRGPYIYSVLESAQAFLSQHPFEELEEPTSESKDASPRHRIQNISRFVWKQANVASELWEKLTARCVDQHRHIERTLEQLLEIKGAMEELSTALDQAESVRETWEPIGDLFIDSLPEHIQSTKLFKEELSPMKDGVKVVNDLAHQLAISDVHLSMENSRSLEQINTRWKQLQASINERLKQLQDAHRDFGPGSQHFLSSSVQVPWERAISPNKVPYYINHQAQTTCWDHPKMTELYQTLADLNNIKFSAYRTAMKLRRVQKALRLDMVTLATALEIFNEHDLQPSDRAMDVVEVIHCLTSLYERLEEERGILVNVPLCVDMSLNWLLNVFDSGRSGKMRALSFKTGIACLCGTEVKEKFQYLFSQVANAGGLCDQRHLGVLLHEAIQVPRQLGEVAAFGGSNVEPSIRSCFRFSHGKPAIEAAQFLEWANLEPQSMVWLAVLHRVTMAEQVKHQTKCSVCRQCPIKGFRYRSLKQFNVDICQTCFLTGRASKGNKLHYPIMEYYTPTTSSENMRDFATTLKNKFRSKQYFSKHPQRGYLPVQSVLEADFSETLAEMENQNCSFFSDSLSPDDSLDEDQYLLRHSSPITDREPAGSQQVPGSLPMDDKGELERILAHLEDENRILQGELRRLKWQHDEAVESPTLATGSPESVQDPRNEELLAEARILRQHKSRLETRMQILEDHNKQLESQLHRLRELLLQPPAESNGNGSAASSLASSPHQSEGGQPRDKEHDTPDTEAAADEVEAKTQEVSVCLEDIMEKLRSAFPNSRGTRVKSPSLASYCSIR", "length": 927, "header": "tr|A0A8V0YN00-1|A0A8V0YN05_CHICK Computationally mapped isoform of Dystrophin related protein 2 OS=Gallus gallus OX=9031 GN=DRP2 PE=4 SV=1 CANONICAL=A0A8V0YN05-1" }, "locus": { "chromosome": "4", "start_pos": 2024799, "end_pos": 2013969, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010038639.1", "url": "https://www.ensembl.org/id/ENSGALT00010038639.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010022356.1", "url": "https://www.ensembl.org/id/ENSGALP00010022356.1" } ] } }, { "isoform_ac": "A0A8V0YN05-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN05/entry#A0A8V0YN05-1", "sequence": { "sequence": "MQPLVMQEWPFVVPRCPEWRVAEQARRASAAHPLSQVKGSQDGTGPSCVTPRAAGSAAGPQAPLEMNLCWNEIKKKSHSLRARLEAFSDHSGKLQVPLQEIIDWLGQKDEELSAQLPLRGDVLLVQQEKETHAAFMEEVKSRGPYIYSVLESAQAFLSQHPFEELEEPTSESKDASPRHRIQNISRFVWKQANVASELWEKLTARCVDQHRHIERTLEQLLEIKGAMEELSTALDQAESVRETWEPIGDLFIDSLPEHIQSTKLFKEELSPMKDGVKVVNDLAHQLAISDVHLSMENSRSLEQINTRWKQLQASINERLKQLQDAHRDFGPGSQHFLSSSVQVPWERAISPNKVPYYINHQAQTTCWDHPKMTELYQTLADLNNIKFSAYRTAMKLRRVQKALRLDMVTLATALEIFNEHDLQPSDRAMDVVEVIHCLTSLYERLEEERGILVNVPLCVDMSLNWLLNVFDSGRSGKMRALSFKTGIACLCGTEVKEKFQYLFSQVANAGGLCDQRHLGVLLHEAIQVPRQLGEVAAFGGSNVEPSIRSCFRFSHGKPAIEAAQFLEWANLEPQSMVWLAVLHRVTMAEQVKHQTKCSVCRQCPIKGFRYRSLKQFNVDICQTCFLTGRASKGNKLHYPIMEYYTPTTSSENMRDFATTLKNKFRSKQYFSKHPQRGYLPVQSVLEADFSETPASSPMLPHADTHSRIEHFASRLAEMENQNCSFFSDSLSPDDSLDEDQYLLRHSSPITDREPAGSQQVPGSLPMDDKGELERILAHLEDENRILQGELRRLKWQHDEAVESPTLATGSPESVQDPRNEELLAEARILRQHKSRLETRMQILEDHNKQLESQLHRLRELLLQPPAESNGNGSAASSLASSPHQSEGGQPRDKEHDTPDTEAAADEVEAKTQEVSVCLEDIMEKLRSAFPNSRGMTSLI", "length": 939, "header": 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"table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YN17-1", "uniprot_ac": "A0A8V0YN17", "uniprot_id": "A0A8V0YN17_CHICK", "mass": { "chemical_mass": 31143.0, "monoisotopic_mass": 31143.0 }, "refseq": {}, "gene_names": [ { "name": "MND1", "type": "recommended", "evidence": [ { "id": "A0A8V0YN17", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN17" } ] } ], "protein_names": [ { "name": "Meiotic nuclear divisions 1", "type": "synonym", "evidence": [ { "id": "A0A8V0YN17", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN17/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Required for proper homologous chromosome pairing and efficient cross-over and intragenic recombination during meiosis.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YUU5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUU5#function" }, { "database": 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"reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MND1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN17", "locus": { "chromosome": "4", "start_pos": 19392259, "end_pos": 19343070, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010014173", "url": "https://www.ensembl.org/id/ENSGALG00010014173" } ] } } ], "crossref": [ { "id": "A0A8V0YN17", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YN17", "database": "AlphaFoldDB", "categories": [] }, { "id": "422399", "url": "https://www.ncbi.nlm.nih.gov/gene/422399", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR005647", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005647", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040453", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040453", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040661", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040661", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YGP0", "url": "https://www.orthodb.org/?gene=A0A8V0YGP0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YGP5", "url": "https://www.orthodb.org/?gene=A0A8V0YGP5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YN17", "url": "https://www.orthodb.org/?gene=A0A8V0YN17", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YPT5", "url": "https://www.orthodb.org/?gene=A0A8V0YPT5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YPU4", "url": "https://www.orthodb.org/?gene=A0A8V0YPU4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YPU9", "url": "https://www.orthodb.org/?gene=A0A8V0YPU9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YUU5", "url": "https://www.orthodb.org/?gene=A0A8V0YUU5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31398", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31398", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31398:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31398:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03962", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03962", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF18517", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18517", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YGP0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGP0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YGP0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGP0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YGP5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGP5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YGP5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGP5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YN17", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN17", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YN17-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN17-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YPT5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPT5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YPT5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPT5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YPU4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPU4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YPU4-1", 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"tr|A0A8V0YN17-1|A0A8V0YN17_CHICK Isoform 1 of Meiotic nuclear divisions 1 OS=Gallus gallus OX=9031 GN=MND1 PE=4 SV=1 CANONICAL=A0A8V0YN17-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YGP0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN17/entry#A0A8V0YGP0-1", "sequence": { "sequence": "MSKKKGLSFEEKRARMMEIFFETKDVFQLKDIEKIASKDKGITSMSVKEVLQSLVDDGMVDTDRIGTSNYFWAFPSKALHARKRKLEELQTQECFEVRSLYAFCQFHLIFSVTFLELVSGKFAETSQKKEILQKGMEKSKIGRENTAERAALMKELAALQQKKEQLKAEIEKYKEYDPDVVEEMRQTSKVAKEAANRWTDNIFAIKSWAKRKFGFEESRIDKSFGIPEDFDYID", "length": 234, "header": "tr|A0A8V0YGP0-1|A0A8V0YGP0_CHICK Computationally mapped isoform of Meiotic nuclear division protein 1 homolog OS=Gallus gallus OX=9031 GN=MND1 PE=3 SV=1 CANONICAL=A0A8V0YN17-1" }, "locus": { "chromosome": "4", "start_pos": 19381422, "end_pos": 19343172, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034090.1", "url": "https://www.ensembl.org/id/ENSGALT00010034090.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020034.1", "url": "https://www.ensembl.org/id/ENSGALP00010020034.1" } ] } }, { "isoform_ac": "A0A8V0YGP5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN17/entry#A0A8V0YGP5-1", "sequence": { "sequence": "MSKKKGLSFEEKRARMMEIFFETKDVFQLKDIEKIASKDKGITSMSVKEVLQSLVDDGMVDTDRIGTSNYFWAFPSKALHARKRKLEELQTQECFEVRSLYAFCQFHLIFSVFAETSQKKEILQKGMEKSKIGRENTAERAALMKELAALQQKKEQLKAEIEKYKEYDPDVVEEMQMNRQQSIWSCFKTTKTTSNGSDLQIIFIEDKKASVGPNKQSSQGGSQQMD", "length": 226, "header": "tr|A0A8V0YGP5-1|A0A8V0YGP5_CHICK Computationally mapped isoform of Meiotic nuclear division protein 1 homolog OS=Gallus gallus OX=9031 GN=MND1 PE=3 SV=1 CANONICAL=A0A8V0YN17-1" }, "locus": { "chromosome": "4", "start_pos": 19380549, "end_pos": 19343172, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034097.1", "url": "https://www.ensembl.org/id/ENSGALT00010034097.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020039.1", "url": "https://www.ensembl.org/id/ENSGALP00010020039.1" } ] } }, { "isoform_ac": "A0A8V0YN17-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN17/entry#A0A8V0YN17-1", "sequence": { "sequence": "MSKKKGLSFEEKRARMMEIFFETKDVFQLKDIEKIASKDKGITSMSVKEVLQSLVDDGMVDTDRIGTSNYFWAFPSKALHARKRKLEELQTQFAETSQKKEILQKGMEKSKIGRENTAERAALMKELAALQQKKEQLKAEIEKYKEYDPDVVEEMQMNRQQSIWSCFKTTKTTSNGSDLQIIFIEDKKASVGCDVLDAAGRRDPAVELLARIEPDPRAFSSCLRMAKFSIHRHWELYFLKMDNVFPDPSDGKMGDYADCSAILHNNSGSLAR", "length": 272, "header": "tr|A0A8V0YN17-1|A0A8V0YN17_CHICK Isoform 1 of Meiotic nuclear divisions 1 OS=Gallus gallus OX=9031 GN=MND1 PE=4 SV=1 CANONICAL=A0A8V0YN17-1" }, "locus": { "chromosome": "4", "start_pos": 19377868, "end_pos": 19343172, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034085.1", "url": "https://www.ensembl.org/id/ENSGALT00010034085.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020031.1", "url": "https://www.ensembl.org/id/ENSGALP00010020031.1" } ] } }, { "isoform_ac": "A0A8V0YPT5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN17/entry#A0A8V0YPT5-1", "sequence": { "sequence": "MSKKKGLSFEEKRARMMEIFFETKDVFQLKDIEKIASKDKGITSMSVKEVLQSLVDDGMVDTDRIGTSNYFWAFPSKALHARKRKLEELQTQFAETSQKKEILQKGMEKSKIGRENTAERAALMKELAALQQKKEQLKAEIEKYKEYDPDVVEEMQMNRQQSIWSCFKTTKTTSNGSDLQIIFIEDKKASVGSLLCLQMM", "length": 200, "header": "tr|A0A8V0YPT5-1|A0A8V0YPT5_CHICK Computationally mapped isoform of Meiotic nuclear division protein 1 homolog OS=Gallus gallus OX=9031 GN=MND1 PE=3 SV=1 CANONICAL=A0A8V0YN17-1" }, "locus": { "chromosome": "4", "start_pos": 19372977, "end_pos": 19343172, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034078.1", "url": "https://www.ensembl.org/id/ENSGALT00010034078.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020027.1", "url": "https://www.ensembl.org/id/ENSGALP00010020027.1" } ] } }, { "isoform_ac": "A0A8V0YPU4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN17/entry#A0A8V0YPU4-1", "sequence": { "sequence": "MSKKKGLSFEEKRARMMEIFFETKDVFQLKDIEKIASKDKGITSMSVKEVLQSLVDDGMVDTDRIGTSNYFWAFPSKALHARKRKLEELQTQECFEVRSLYAFCQFHLIFSVFAETSQKKEILQKGMEKSKIGRENTAERAALMKELAALQQKKEQLKAEIEKYKEYDPDVVEEMQMNRQQSIWSCFKTTKTTSNGSDLQIIFIEDKKASVGSVKWSLPWPC", "length": 222, "header": "tr|A0A8V0YPU4-1|A0A8V0YPU4_CHICK Computationally mapped isoform of Meiotic nuclear division protein 1 homolog OS=Gallus gallus OX=9031 GN=MND1 PE=3 SV=1 CANONICAL=A0A8V0YN17-1" }, "locus": { "chromosome": "4", "start_pos": 19372337, "end_pos": 19343172, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034095.1", "url": "https://www.ensembl.org/id/ENSGALT00010034095.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020037.1", "url": "https://www.ensembl.org/id/ENSGALP00010020037.1" } ] } }, { "isoform_ac": "A0A8V0YPU9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN17/entry#A0A8V0YPU9-1", "sequence": { "sequence": "MSKKKGLSFEEKRARMMEIFFETKDVFQLKDIEKIASKDKGISKSSMSVKEVLQSLVDDGMVDTDRIGTSNYFWAFPSKALHARKRKLEELQTQFAETSQKKEILQKGMEKSKIGRENTAERAALMKELAALQQKKEQLKAEIEKYKEYDPDVVEEMRQTSKVAKEAANRWTDNIFAIKSWAKRKFGFEESRIDKSFGIPEDFDYID", "length": 207, "header": "tr|A0A8V0YPU9-1|A0A8V0YPU9_CHICK Computationally mapped isoform of Meiotic nuclear division protein 1 homolog OS=Gallus gallus OX=9031 GN=MND1 PE=3 SV=1 CANONICAL=A0A8V0YN17-1" }, "locus": { "chromosome": "4", "start_pos": 19381422, "end_pos": 19343172, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034104.1", "url": "https://www.ensembl.org/id/ENSGALT00010034104.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020043.1", "url": "https://www.ensembl.org/id/ENSGALP00010020043.1" } ] } }, { "isoform_ac": "A0A8V0YUU5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN17/entry#A0A8V0YUU5-1", "sequence": { "sequence": "MSKKKGLSFEEKRARMMEIFFETKDVFQLKDIEKIASKDKGITSMSVKEVLQSLVDDGMVDTDRIGTSNYFWAFPSKALHARKRKLEELQTQECFEVRSLYAFCQFHLIFSVFAETSQKKEILQKGMEKSKIGRENTAERAALMKELAALQQKKEQLKAEIEKYKEYDPDVVEEMQMNRQQSIWSCFKTTKTTSNGSDLQIIFIEDKKASVG", "length": 212, "header": "tr|A0A8V0YUU5-1|A0A8V0YUU5_CHICK Computationally mapped isoform of Meiotic nuclear division protein 1 homolog OS=Gallus gallus OX=9031 GN=MND1 PE=3 SV=1 CANONICAL=A0A8V0YN17-1" }, "locus": { "chromosome": "4", "start_pos": 19372096, "end_pos": 19343172, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034083.1", "url": "https://www.ensembl.org/id/ENSGALT00010034083.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020030.1", "url": "https://www.ensembl.org/id/ENSGALP00010020030.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "homologous chromosome pairing at meiosis", "id": "GO:0007129", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007129", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YN17", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN17" } ], "pmid": "" }, { "name": "reciprocal meiotic recombination", "id": "GO:0007131", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007131", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YN17", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN17" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YN17", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN17" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "double-stranded DNA binding", "id": "GO:0003690", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003690", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YN17", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN17" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 175, "end_pos": 177, "annotation": "n_glycosylation_sequon" }, { "start_pos": 265, "end_pos": 267, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YN17", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN17" }, { "id": "PF03962", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03962" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Mnd1 HTH", "eco_id": "ECO_0000259", "start_pos": 16, "end_pos": 75, "start_aa": "Met", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 175, "end_pos": 177 }, { "start_pos": 265, "end_pos": 267 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YN26-1", "uniprot_ac": "A0A8V0YN26", "uniprot_id": "A0A8V0YN26_CHICK", "mass": { "chemical_mass": 65252.0, "monoisotopic_mass": 65252.0 }, "refseq": {}, "gene_names": [ { "name": "CCDC50", "type": "recommended", "evidence": [ { "id": "A0A8V0YN26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN26" } ] } ], "protein_names": [ { "name": "Coiled-coil domain containing 50", "type": "synonym", "evidence": [ { "id": "A0A8V0YN26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN26/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YN26", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN26" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CCDC50", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN26", "locus": { "chromosome": "9", "start_pos": 13352375, "end_pos": 13397907, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010014209", "url": "https://www.ensembl.org/id/ENSGALG00010014209" } ] } } ], "crossref": [ { "id": "A0A8V0YN26", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YN26", "database": "AlphaFoldDB", "categories": [] }, { "id": "424906", "url": "https://www.ncbi.nlm.nih.gov/gene/424906", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR029311", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029311", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039303", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039303", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "TWNWEKQ", "url": "https://omabrowser.org/oma/group/TWNWEKQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YN26", "url": "https://www.orthodb.org/?gene=A0A8V0YN26", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YN34", "url": "https://www.orthodb.org/?gene=A0A8V0YN34", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YN96", "url": "https://www.orthodb.org/?gene=A0A8V0YN96", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YNA5", "url": "https://www.orthodb.org/?gene=A0A8V0YNA5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YQ01", "url": "https://www.orthodb.org/?gene=A0A8V0YQ01", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YV29", "url": "https://www.orthodb.org/?gene=A0A8V0YV29", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22115", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22115", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22115:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22115:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15295", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15295", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YN26", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN26", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YN26-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN26-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YN34", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN34", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YN34-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN34-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YN96", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN96", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YN96-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN96-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YNA5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNA5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YNA5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNA5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQ01", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ01", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQ01-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ01-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YV29", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YV29", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YV29-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YV29-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MCPLSTDFGLSRAVPLLGSPSVCIDIFSFFSPSFLLILILLALFPHTVCRDFAVLEDHTLAHNLQEQEIEHHLATNIQRNRLVQHDLQVAKQLQEEEDLKARAQIQKRQKDLERQDSEIAQEIQVKLVFEAEQRRRQEEKDEDIARLLQQKELQEEKKRKKHYPESQGHKVYEDSYYSENGEHLRADPREQVSEPRRARGDNRRTHRQREHRKARSPLSDSASQHRHAPLEDRHRSPQPSEATNSHRQECKSASQGGSGRPTSLVLEREADRGAGEHTGNWELQDRSAPGREKSWRPLSLDLESERGLSEQARCSRKPTRRDGAKHLPVLDVELEAEQETWRRGGSQLVHPENRKSRYRGHSSHGMEHESKSQEDHRRGEERDCKRAGHRRPSPSPHAVTQEKVGDYRRDSGTKLRGTKQTVYDKPRREQELSDAEIARKLQEEELLANQADQMAAQVAQDEEIARLLMAEEKKAFKKGKEKEKSSFERKRNDQDWKHDASESPRSRSKEGPETQRHKGDKSSRSQPLLDDFEHARYYTSQPSPLRQFSKPEHSPKGSRRKQ", "length": 562, "header": "tr|A0A8V0YN26-1|A0A8V0YN26_CHICK Isoform 1 of Coiled-coil domain containing 50 OS=Gallus gallus OX=9031 GN=CCDC50 PE=4 SV=1 CANONICAL=A0A8V0YN26-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YN26-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN26/entry#A0A8V0YN26-1", "sequence": { "sequence": "MCPLSTDFGLSRAVPLLGSPSVCIDIFSFFSPSFLLILILLALFPHTVCRDFAVLEDHTLAHNLQEQEIEHHLATNIQRNRLVQHDLQVAKQLQEEEDLKARAQIQKRQKDLERQDSEIAQEIQVKLVFEAEQRRRQEEKDEDIARLLQQKELQEEKKRKKHYPESQGHKVYEDSYYSENGEHLRADPREQVSEPRRARGDNRRTHRQREHRKARSPLSDSASQHRHAPLEDRHRSPQPSEATNSHRQECKSASQGGSGRPTSLVLEREADRGAGEHTGNWELQDRSAPGREKSWRPLSLDLESERGLSEQARCSRKPTRRDGAKHLPVLDVELEAEQETWRRGGSQLVHPENRKSRYRGHSSHGMEHESKSQEDHRRGEERDCKRAGHRRPSPSPHAVTQEKVGDYRRDSGTKLRGTKQTVYDKPRREQELSDAEIARKLQEEELLANQADQMAAQVAQDEEIARLLMAEEKKAFKKGKEKEKSSFERKRNDQDWKHDASESPRSRSKEGPETQRHKGDKSSRSQPLLDDFEHARYYTSQPSPLRQFSKPEHSPKGSRRKQ", "length": 562, "header": "tr|A0A8V0YN26-1|A0A8V0YN26_CHICK Isoform 1 of Coiled-coil domain containing 50 OS=Gallus gallus OX=9031 GN=CCDC50 PE=4 SV=1 CANONICAL=A0A8V0YN26-1" }, "locus": { "chromosome": "9", "start_pos": 13378301, "end_pos": 13358382, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034222.1", "url": "https://www.ensembl.org/id/ENSGALT00010034222.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020104.1", "url": "https://www.ensembl.org/id/ENSGALP00010020104.1" } ] } }, { "isoform_ac": "A0A8V0YN34-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN26/entry#A0A8V0YN34-1", "sequence": { "sequence": "PAGLGVGSLCRDFAVLEDHTLAHNLQEQEIEHHLATNIQRNRLVQHDLQVAKQLQEEEDLKARAQIQKRQKDLERQDSEIAQEIQVKLVFEAEQRRRQEEKDEDIARLLQQKELQEEKKRKKHYPESQGHKVYEDSYYSENGGTKLRGTKQTVYDKPRREQELSDAEIARKLQEEELLANQADQMAAQVAQDEEIARLLMAEEKKAFKKGKEKEKSSFERKRNDQDWKHDASESPRSRSKEGPETQRHKGDKSSRSQPLLDDFEHARYYTSQPSPLRQFSKPEHSPKGSRRKQ", "length": 293, "header": "tr|A0A8V0YN34-1|A0A8V0YN34_CHICK Computationally mapped isoform of Coiled-coil domain containing 50 OS=Gallus gallus OX=9031 GN=CCDC50 PE=4 SV=1 CANONICAL=A0A8V0YN26-1" }, "locus": { "chromosome": "9", "start_pos": 13379302, "end_pos": 13358382, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034227.1", "url": "https://www.ensembl.org/id/ENSGALT00010034227.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020109.1", "url": "https://www.ensembl.org/id/ENSGALP00010020109.1" } ] } }, { "isoform_ac": "A0A8V0YN96-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN26/entry#A0A8V0YN96-1", "sequence": { "sequence": "MAEIGIDQSKLPGVKEVCRDFAVLEDHTLAHNLQEQEIEHHLATNIQRNRLVQHDLQVAKQLQEEEDLKARAQIQKRQKDLERQDSEIAQEIQVKLVFEAEQRRRQEEKDEDIARLLQQKELQEEKKRKKHYPESQGHKVYEDSYYSENGEHLRADPREQVSEPRRARGDNRRTHRQREHRKARSPLSDSASQHRHAPLEDRHRSPQPSEATNSHRQECKSASQGGSGRPTSLVLEREADRGAGEHTGNWELQDRSAPGREKSWRPLSLDLESERGLSEQARCSRKPTRRDGAKHLPVLDVELEAEQETWRRGGSQLVHPENRKSRYRGHSSHGMEHESKSQEDHRRGEERDCKRAGHRRPSPSPHAVTQEKVGDYRRDSGTKLRGTKQTVYDKPRREQELSDAEIARKLQEEELLANQADQMAAQVAQDEEIARLLMAEEKKAFKKGKEKEKSSFERKRNDQDWKHDASESPRSRSKEGPETQRHKGDKSSRSQPLLDDFEHARYYTSQPSPLRQFSKPEHSPKGSRRKQ", "length": 531, "header": "tr|A0A8V0YN96-1|A0A8V0YN96_CHICK Computationally mapped isoform of Coiled-coil domain containing 50 OS=Gallus gallus OX=9031 GN=CCDC50 PE=4 SV=1 CANONICAL=A0A8V0YN26-1" }, "locus": { "chromosome": "9", "start_pos": 13391942, "end_pos": 13358382, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034231.1", "url": "https://www.ensembl.org/id/ENSGALT00010034231.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020112.1", "url": "https://www.ensembl.org/id/ENSGALP00010020112.1" } ] } }, { "isoform_ac": "A0A8V0YNA5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN26/entry#A0A8V0YNA5-1", "sequence": { "sequence": "RGRGFLVFSSTSSEHLKTSPTSCISVCRDFAVLEDHTLAHNLQEQEIEHHLATNIQRNRLVQHDLQVAKQLQEEEDLKARAQIQKRQKDLERQDSEIAQEIQVKLVFEAEQRRRQEEKDEDIARLLQQKELQEEKKRKKHYPESQGHKVYEDSYYSENGGTKLRGTKQTVYDKPRREQELSDAEIARKLQEEELLANQADQMAAQVAQDEEIARLLMAEEKKAFKKGKEKEKSSFERKRNDQDWKHDASESPRSRSKEGPETQRHKGDKSSRSQPLLDDFEHARYYTSQPSPLRQFSKPEHSPKGSRRKQ", "length": 310, "header": "tr|A0A8V0YNA5-1|A0A8V0YNA5_CHICK Computationally mapped isoform of Coiled-coil domain containing 50 OS=Gallus gallus OX=9031 GN=CCDC50 PE=4 SV=1 CANONICAL=A0A8V0YN26-1" }, "locus": { "chromosome": "9", "start_pos": 13397827, "end_pos": 13358382, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034249.1", "url": "https://www.ensembl.org/id/ENSGALT00010034249.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020122.1", "url": "https://www.ensembl.org/id/ENSGALP00010020122.1" } ] } }, { "isoform_ac": "A0A8V0YQ01-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN26/entry#A0A8V0YQ01-1", "sequence": { "sequence": "MQAVFKVCMAENRGSGSEQPSVCRDFAVLEDHTLAHNLQEQEIEHHLATNIQRNRLVQHDLQVAKQLQEEEDLKARAQIQKRQKDLERQDSEIAQEIQVKLVFEAEQRRRQEEKDEDIARLLQQKELQEEKKRKKHYPESQGHKVYEDSYYSENGGTKLRGTKQTVYDKPRREQELSDAEIARKLQEEELLANQADQMAAQVAQDEEIARLLMAEEKKAFKKGKEKEKSSFERKRNDQDWKHDASESPRSRSKEGPETQRHKGDKSSRSQPLLDDFEHARYYTSQPSPLRQFSKPEHSPKGSRRKQ", "length": 306, "header": "tr|A0A8V0YQ01-1|A0A8V0YQ01_CHICK Computationally mapped isoform of Coiled-coil domain containing 50 OS=Gallus gallus OX=9031 GN=CCDC50 PE=4 SV=1 CANONICAL=A0A8V0YN26-1" }, "locus": { "chromosome": "9", "start_pos": 13378398, "end_pos": 13358382, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034214.1", "url": "https://www.ensembl.org/id/ENSGALT00010034214.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020098.1", "url": "https://www.ensembl.org/id/ENSGALP00010020098.1" } ] } }, { "isoform_ac": "A0A8V0YV29-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN26/entry#A0A8V0YV29-1", "sequence": { "sequence": "VCRDFAVLEDHTLAHNLQEQEIEHHLATNIQRNRLVQHDLQVAKQLQEEEDLKARAQIQKRQKDLERQDSEIAQEIQVKLVFEAEQRRRQEEKDEDIARLLQQKELQEEKKRKKHYPESQGHKVYEDSYYSENGGTKLRGTKQTVYDKPRREQELSDAEIARKLQEEELLANQADQMAAQVAQDEEIARLLMAEEKKAFKKGKEKEKSSFERKRNDQDWKHDASESPRSRSKEGPETQRHKGDKSSRSQPLLDDFEHARYYTSQPSPLRQFSKPEHSPKGSRRKQ", "length": 285, "header": "tr|A0A8V0YV29-1|A0A8V0YV29_CHICK Computationally mapped isoform of Coiled-coil domain containing 50 OS=Gallus gallus OX=9031 GN=CCDC50 PE=4 SV=1 CANONICAL=A0A8V0YN26-1" }, "locus": { "chromosome": "9", "start_pos": 13397317, "end_pos": 13358382, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034239.1", "url": "https://www.ensembl.org/id/ENSGALT00010034239.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020116.1", "url": "https://www.ensembl.org/id/ENSGALP00010020116.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A286ZUX4-1", "protein_name": "Coiled-coil domain containing 50", "gene_name": "CCDC50", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSEVSIDQSKLPGVKEVCRDFAVLEDHTLAHSLQEQEIEHHLASNVQRNRLVQHDLQVAKQLQEEDLKAQAQLQKRYKDLEQQDCEIAQEIQEKLTIEAERRRIQEKKDEDIARLLQEKELQEEKKRKKHFPEASGANAYGDSYYYEDGDHPRSRRARELGSGFSRSCRLQSEEKTVKQRKEKCKRPQENLEELEEQCPSEKPLSSSSLGKVRDDPPMNTEQPERKQPGPEKLQRPPLPRISGEVFLSTESDDWEAHHSHRTRSGEKHARHQDRLSPKSSQKAGLPCKEAVYGRDHGQGVHRERKHRPRTRPFSESEERFQLHDPGVKPRVMKDTVSTPSRVTHRDQEWSDAEIARKLQEEEILAIQVDMRAAQVAQDEEIARLLMAEEKKAYKKAREREKSSLDKRKHDPEWKPKTAKSAHSKSKESDEPHRSKNDRPARPPPPTMTDAEDLDYTHFTNQHNSTRHFSKAESSHKGFHYKP", "length": 482 }, "evidence": [ { "id": "A0A8V0YN26", "url": "https://omabrowser.org/oma/group/A0A8V0YN26/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A3Q1MBX8-1", "protein_name": "Coiled-coil domain containing 50", "gene_name": "CCDC50", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAEVTIDQSKLPGVKEVCRDFAVLEDHTLAHSLQEQEIEHHLASNVQRNRLVQHDLQVAKQLQEEDLKAQAQLQKRYKDLEQQDCEIAQEIQEKLAIEAERRRIQEKKDEDIARLLQEKELQEEKKRKKHFPESSGVSAYGDSYYYEDGDQPRSRRAREVGSGSSRPCRLQHEEKTVKHRRERPRHPQENLGEPEEHCASEKPPSSSSSGQVRDDPQGNTEPERKRCGHERLRRPPLPKISGEVLLSTESDDWEAHSSHRTRKWEKQFRQQDQLSPKTSRKAGLPCKEAIYRWDHGQGEHRERNRRPRTPPFSESEEQLPLRDTGMKPRVMKEAVSTPSRVTHRDQEWYDAEIARKLQEEEILATQVDMRAAQVAQDEEIARLLMAEEKKAYKKAREREKSSLDKRKHDPEWKPKTAKSAHSKSKESDEPHRSKNDRPARPPPPPMTDAEGLDFTSSGNQHNSTRHYSKSESSHKGFHYKP", "length": 481 }, "evidence": [ { "id": "A0A8V0YN26", "url": "https://omabrowser.org/oma/group/A0A8V0YN26/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q810U0-1", "protein_name": "Coiled-coil domain-containing protein 50", "gene_name": "Ccdc50", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MADVSVDQSKLPGVKEVCRDFAVLEDHTLAHSLQEQEIEHHLASNIQRNRLVQHDLQVAKQLQEEDLKAQAQLQKRYKALEQHDCEIAQEIQEKLTIEAERRRIQEKKDEDIARLLQEKELQEEKKRKKHTPEFSGGSASGDNYYYEDGGMKSRGINEAVSAPARVSHRDQEWYDAEIARKLQEEELLATHMDIRAAQVAQDEEIARLLMAEEKKAYKKAKDREKSSLDKRKHDYDCKSKAKSAHSKSKEGDETQRAKIDRPSRPPPPAAMAPEDVDPTHFTNQHSNTRHFSKSESSHKGFHNKQ", "length": 305 }, "evidence": [ { "id": "A0A8V0YN26", "url": "https://omabrowser.org/oma/group/A0A8V0YN26/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q810U5-1", "protein_name": "Coiled-coil domain-containing protein 50", "gene_name": "Ccdc50", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MADVSVDQSKLPGVKEVCRDFAVLEDHTLAHSLQEQEIEHHLASNIQRNRLVQHDLQVAKQLQEEDLKAQAQLQKRYKALEQHDCEIAQEIQEKLTIEAERRRIQEKKDEDIARLLQEKELQEEKRRKKHTPEFSGGSVFGDNYYHEDGGMKPRGIKEAVSTPARASHRDQEWYDAEIARKLQEEELLATHVDMRAAQVAQDEEIARLLMAEEKKAYKKAKEREKSSLDKRKHDPECKLKAKSAHSKSKEGDEAHRSKIDRPSRPPPPTMMGLEDTDPTHFTNQHSTTWHLPKSESSQKGFHNKQ", "length": 305 }, "evidence": [ { "id": "A0A8V0YN26", "url": "https://omabrowser.org/oma/group/A0A8V0YN26/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8IVM0-1", "protein_name": "Coiled-coil domain-containing protein 50", "gene_name": "CCDC50", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAEVSIDQSKLPGVKEVCRDFAVLEDHTLAHSLQEQEIEHHLASNVQRNRLVQHDLQVAKQLQEEDLKAQAQLQKRYKDLEQQDCEIAQEIQEKLAIEAERRRIQEKKDEDIARLLQEKELQEEKKRKKHFPEFPATRAYADSYYYEDGGMKPRVMKEAVSTPSRMAHRDQEWYDAEIARKLQEEELLATQVDMRAAQVAQDEEIARLLMAEEKKAYKKAKEREKSSLDKRKQDPEWKPKTAKAANSKSKESDEPHHSKNERPARPPPPIMTDGEDADYTHFTNQQSSTRHFSKSESSHKGFHYKH", "length": 306 }, "evidence": [ { "id": "A0A8V0YN26", "url": "https://omabrowser.org/oma/group/A0A8V0YN26/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YN26", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN26" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YN26", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN26" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "ubiquitin protein ligase binding", "id": "GO:0031625", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031625", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YN26", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN26" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YN26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN26" }, { "id": "PF15295", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15295" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Coiled-coil", "eco_id": "ECO_0000259", "start_pos": 47, "end_pos": 160, "start_aa": "Thr", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YN55-1", "uniprot_ac": "A0A8V0YN55", "uniprot_id": "A0A8V0YN55_CHICK", "mass": { "chemical_mass": 81587.0, "monoisotopic_mass": 81587.0 }, "refseq": {}, "gene_names": [ { "name": "SPATA5L1", "type": "recommended", "evidence": [ { "id": "A0A8V0YN55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN55" } ] } ], "protein_names": [ { "name": "ATPase family gene 2 protein homolog B", "type": "recommended", "evidence": [ { "id": "A0A8V0YN55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN55/entry#names_and_taxonomy" } ] }, { "name": "3.6.4.10", "type": "synonym", "evidence": [ { "id": "A0A8V0YN55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN55/entry#names_and_taxonomy" } ] }, { "name": "AFG2 AAA ATPase homolog B", "type": "synonym", "evidence": [ { "id": "A0A8V0YN55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN55/entry#names_and_taxonomy" } ] }, { "name": "Ribosome biogenesis protein SPATA5L1", "type": "synonym", "evidence": [ { "id": "A0A8V0YN55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN55/entry#names_and_taxonomy" } ] }, { "name": "Spermatogenesis-associated protein 5-like protein 1", "type": "synonym", "evidence": [ { "id": "A0A8V0YN55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN55/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "ATP-dependent chaperone part of the 55LCC heterohexameric ATPase complex which is chromatin-associated and promotes replisome proteostasis to maintain replication fork progression and genome stability. Required for replication fork progression, sister chromatid cohesion, and chromosome stability. The ATPase activity is specifically enhanced by replication fork DNA and is coupled to cysteine protease-dependent cleavage of replisome substrates in response to replication fork damage. Uses ATPase activity to process replisome substrates in S-phase, facilitating their proteolytic turnover from chromatin to ensure DNA replication and mitotic fidelity. Plays an essential role in the cytoplasmic maturation steps of pre-60S ribosomal particles by promoting the release of shuttling protein RSL24D1/RLP24 from the pre-ribosomal particles.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YN55", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN55#function" }, { "database": "UniProtKB", "id": "ARBA00053521", "url": "https://www.uniprot.org/uniprotkb/ARBA00053521#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YN55", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN55" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SPATA5L1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN55", "locus": {} } ], "crossref": [ { "id": "A0A8V0YN55", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YN55", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd19503", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd19503", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR003593", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003593", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003959", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003959", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003960", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003960", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041569", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041569", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050168", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050168", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YN55", "url": "https://www.orthodb.org/?gene=A0A8V0YN55", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23077", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23077", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23077:SF194", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23077:SF194", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00004", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00004", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17862", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17862", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YN55", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN55", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YN55-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN55-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEPAPLKLLPPDPGDEGTQRCRLGPAALSSLGVRLGAPLRISLPAGCCLCTAWPRPDLADGYVQADPACSTGLTAAELRGLTLSPGLLQPLSSRRLRGAAVRAVLRGGAPRRAAGLQEAVRDLLTNVYVSPHYVVTVGPNVRAPVLHVEILSVDPVTEEAGLITPQTSVTIKEVITLERYRLLTEDTAKIPVAGLDDVGESLKEMVDLPFRFPRTFKKLGLSVPNGVLLVGPPGVGKTLLVKAVAREAGAYLLCISGPALYGSRPGESEENLRSVFEKGREMSCEGPTVLFIDEIDALCPKRGSSNSAPEDRLVAQLLTLLDGVGRKDRMVVVAATNRPDALDPALRRPGRFDREVIIGTPTLTQRRSILQMLTCSMPISTDIDLVKLAEMTTGYVGADLTALCREAAMQAVFHSSLDSAEVLINMADFQEAFKKIQPSSFRSAIGLKECKPITWEQIGGLEDVKLKLKQSVEWPMKFPQAFARMGLARPKGVLLYGPSGCAKTTLVKAVATSCHCSFLSVSGAELFSPYVGDSEKILSQVFRQARANTPAIIFLDEIDSILGSRSHSKSGHGVSERVLSVLLNELDGVGLKVTERRGNKLQLEGRCEELSDEERQLEFQETLSRDFMVVAATNRPDMLDDALLRPGRLDRVIYVPPPDLKGRLSILKICTEKIPLDTDVSLQDIAALTDLFSGADIENLCKEAALLALQENGLEATAVKHGHFVKSLETVKPSLSMKDLEFYEKIYSQELTT", "length": 753, "header": "tr|A0A8V0YN55-1|A0A8V0YN55_CHICK Isoform 1 of ATPase family gene 2 protein homolog B OS=Gallus gallus OX=9031 GN=SPATA5L1 PE=1 SV=1 CANONICAL=A0A8V0YN55-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YN55-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN55/entry#A0A8V0YN55-1", "sequence": { "sequence": "MEPAPLKLLPPDPGDEGTQRCRLGPAALSSLGVRLGAPLRISLPAGCCLCTAWPRPDLADGYVQADPACSTGLTAAELRGLTLSPGLLQPLSSRRLRGAAVRAVLRGGAPRRAAGLQEAVRDLLTNVYVSPHYVVTVGPNVRAPVLHVEILSVDPVTEEAGLITPQTSVTIKEVITLERYRLLTEDTAKIPVAGLDDVGESLKEMVDLPFRFPRTFKKLGLSVPNGVLLVGPPGVGKTLLVKAVAREAGAYLLCISGPALYGSRPGESEENLRSVFEKGREMSCEGPTVLFIDEIDALCPKRGSSNSAPEDRLVAQLLTLLDGVGRKDRMVVVAATNRPDALDPALRRPGRFDREVIIGTPTLTQRRSILQMLTCSMPISTDIDLVKLAEMTTGYVGADLTALCREAAMQAVFHSSLDSAEVLINMADFQEAFKKIQPSSFRSAIGLKECKPITWEQIGGLEDVKLKLKQSVEWPMKFPQAFARMGLARPKGVLLYGPSGCAKTTLVKAVATSCHCSFLSVSGAELFSPYVGDSEKILSQVFRQARANTPAIIFLDEIDSILGSRSHSKSGHGVSERVLSVLLNELDGVGLKVTERRGNKLQLEGRCEELSDEERQLEFQETLSRDFMVVAATNRPDMLDDALLRPGRLDRVIYVPPPDLKGRLSILKICTEKIPLDTDVSLQDIAALTDLFSGADIENLCKEAALLALQENGLEATAVKHGHFVKSLETVKPSLSMKDLEFYEKIYSQELTT", "length": 753, "header": "tr|A0A8V0YN55-1|A0A8V0YN55_CHICK Isoform 1 of ATPase family gene 2 protein homolog B OS=Gallus gallus OX=9031 GN=SPATA5L1 PE=1 SV=1 CANONICAL=A0A8V0YN55-1" }, "locus": { "chromosome": "10", "start_pos": 10689599, "end_pos": 10682929, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010038759.1", "url": "https://www.ensembl.org/id/ENSGALT00010038759.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010022418.1", "url": "https://www.ensembl.org/id/ENSGALP00010022418.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 136, "start_aa": "Thr", "end_pos": 136, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr136", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 7, "go_terms": [ { "name": "autophagosome maturation", "id": "GO:0097352", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097352", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YN55", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN55" } ], "pmid": "" }, { "name": "ribosomal large subunit biogenesis", "id": "GO:0042273", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042273", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YN55", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN55" } ], "pmid": "" }, { "name": "DNA replication", "id": "GO:0006260", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006260", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YN55", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN55" } ], "pmid": "" }, { "name": "proteasome-mediated ubiquitin-dependent protein catabolic process", "id": "GO:0043161", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043161", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YN55", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN55" } ], "pmid": "" }, { "name": "mitotic spindle disassembly", "id": "GO:0051228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051228", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YN55", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN55" } ], "pmid": "" }, { "name": "retrograde protein transport, ER to cytosol", "id": "GO:0030970", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030970", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YN55", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN55" } ], "pmid": "" }, { "name": "regulation of ribosome biogenesis", "id": "GO:0090069", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090069", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YN55", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN55" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "preribosome binding", "id": "GO:1990275", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990275", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YN55", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN55" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YN55", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN55" } ], "pmid": "" }, { "name": "polyubiquitin modification-dependent protein binding", "id": "GO:0031593", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031593", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YN55", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN55" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YN55", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN55" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YN55", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN55" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "VCP-NPL4-UFD1 AAA ATPase complex", "id": "GO:0034098", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034098", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YN55", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN55" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YN55", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN55" } ], "pmid": "" }, { "name": "spindle", "id": "GO:0005819", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005819", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YN55", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN55" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YN55", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN55" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YN55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN55" }, { "id": "SM00382", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00382" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "AAA+ ATPase", "eco_id": "ECO_0000259", "start_pos": 223, "end_pos": 362, "start_aa": "Val", "end_aa": "Thr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "3.6.4.10", "ec_name": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "3.6.4.10", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.10" }, { "id": "3.6.4.10", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=3.6.4.10" } ] } ], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 136 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YN72-1", "uniprot_ac": "A0A8V0YN72", "uniprot_id": "A0A8V0YN72_CHICK", "mass": { "chemical_mass": 29061.0, "monoisotopic_mass": 29061.0 }, "refseq": { "ac": "XP_419413", "name": "RRP15-like protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_419413" }, "gene_names": [ { "name": "RRP15", "type": "recommended", "evidence": [ { "id": "A0A8V0YN72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN72" } ] }, { "name": "RRP15", "type": "synonym", "evidence": [ { "id": "XP_419413", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_419413" } ] } ], "protein_names": [ { "name": "RRP15-like protein", "type": "recommended", "evidence": [ { "id": "A0A8V0YN72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN72/entry#names_and_taxonomy" } ] }, { "name": "RRP15-like protein", "type": "synonym", "evidence": [ { "id": "XP_419413", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_419413" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052534.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_419413.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_419413", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_419413" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YN72", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN72" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RRP15", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN72", "locus": { "chromosome": "3", "start_pos": 19110932, "end_pos": 19139744, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010016141", "url": "https://www.ensembl.org/id/ENSGALG00010016141" } ] } } ], "crossref": [ { "id": "A0A8V0YN72", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YN72", "database": "AlphaFoldDB", "categories": [] }, { "id": "421353", "url": "https://www.ncbi.nlm.nih.gov/gene/421353", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR012459", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012459", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:421353", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:421353", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "FVKQRFY", "url": "https://omabrowser.org/oma/group/FVKQRFY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YN72", "url": "https://www.orthodb.org/?gene=A0A8V0YN72", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13245", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13245", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13245:SF14", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13245:SF14", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07890", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07890", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_419413", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_419413", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YN72", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN72", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YN72-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN72-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAAVESSRGQAAAGEEAASDSEISSGLPDDSYSSGDEALDGDDEDEAAVVEHVAEETANSKAGPGSGWADAMAKVLNKKIPQNKSIILAKSKKLEKEREKERQERLEKRRKLDKKREWEMMCRVKPDVVKDRDRERNLQRIATRGVVQLFNAVRTHQKNVDEKVKKGARSERQRAKLLSSVSKKDFINVLRSMEGAKGNRNSARKAAKSKQGEVKSEEGPEWNILRDDFMMGASMKDWDKESDGEGNIEQGGGLKQEDGSD", "length": 262, "header": "tr|A0A8V0YN72-1|A0A8V0YN72_CHICK Isoform 1 of RRP15-like protein OS=Gallus gallus OX=9031 GN=RRP15 PE=1 SV=1 CANONICAL=A0A8V0YN72-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YN72-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN72/entry#A0A8V0YN72-1", "sequence": { "sequence": "MAAAVESSRGQAAAGEEAASDSEISSGLPDDSYSSGDEALDGDDEDEAAVVEHVAEETANSKAGPGSGWADAMAKVLNKKIPQNKSIILAKSKKLEKEREKERQERLEKRRKLDKKREWEMMCRVKPDVVKDRDRERNLQRIATRGVVQLFNAVRTHQKNVDEKVKKGARSERQRAKLLSSVSKKDFINVLRSMEGAKGNRNSARKAAKSKQGEVKSEEGPEWNILRDDFMMGASMKDWDKESDGEGNIEQGGGLKQEDGSD", "length": 262, "header": "tr|A0A8V0YN72-1|A0A8V0YN72_CHICK Isoform 1 of RRP15-like protein OS=Gallus gallus OX=9031 GN=RRP15 PE=1 SV=1 CANONICAL=A0A8V0YN72-1" }, "locus": { "chromosome": "3", "start_pos": 19139727, "end_pos": 19114887, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010038803.1", "url": "https://www.ensembl.org/id/ENSGALT00010038803.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010022438.1", "url": "https://www.ensembl.org/id/ENSGALP00010022438.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:421353", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:421353", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "Q06511-1", "protein_name": "Ribosomal RNA-processing protein 15", "gene_name": "RRP15", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MGSKHRVDTKDKKRTRKNAEFGREKRNSGNQELSNEPEKDTIMEGDEAEEDEQNSSSDESSKIIDNEQSDAEEDDDEEEEDDDFPRKKKSKNSKHDDGSTGFSAAVNAILSSHLKAYDRKDPIMARNKKVLKQSESEKLEYKAKKALLAEKKKLLGKARKTDIIPIASGEDRSENIRKVLEKETALRKIAQKGAVKLFNAILATQVKTEKEVSENLSEIKNKEEKKELITEVSKEKFLDLVKAAAGSDNE", "length": 250 }, "evidence": [ { "id": "A0A8V0YN72", "url": "https://omabrowser.org/oma/group/A0A8V0YN72/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q3T062-1", "protein_name": "RRP15-like protein", "gene_name": "RRP15", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAAAVGDSRVSAGKKLKISLRKKRMKMVVASVASELEDKDKDASDNEGSLGSCGLEKDHFSSGDEAVEADNEDEAEPREDDNDSAAEATAGANAGWADAMARILSKKIPESKPTILVRNKELEKEKEKLKQERLEKRKQLDKKREWEMMCRVKPDVVKDKETERNLQRIATRGVVQLFNAVQKHQKNVDEKVKEAGGSIRKRAKLISSVSKKDFISVLRGMDGSASEKNSAGKNSKAKQTEAKSEEGPGWTILRDDFMMGASMKDWDKESDGPDGSRLGCGSDSDT", "length": 286 }, "evidence": [ { "id": "A0A8V0YN72", "url": "https://omabrowser.org/oma/group/A0A8V0YN72/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q5M947-1", "protein_name": "RRP15-like protein", "gene_name": "Rrp15", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAAAVQDSRVNPGGKLKRSPKKKKKMKKVAKAAVSKLEDELKDSSGGEGSCESEMDDSDDGAAEADSEDNVESCEEENEVAAESSAGTNSGWADAMAKILNKKTPKSKPTILTKNKELEKEKEKLKQERLEKRKQIDKKREWEMLCRVKPDVIKDKEAERNLQRIATRGVVQLFNAVQKHQRNVDEKVKEVGGSIRKRAKLMSTVSKKDFISVLRGMDGASENSSAGKSPKARQTEVKSEEGPGWKILRDDFMMGASMKDWDKESEGEEPADGQAGSASH", "length": 280 }, "evidence": [ { "id": "A0A8V0YN72", "url": "https://omabrowser.org/oma/group/A0A8V0YN72/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9CYX7-1", "protein_name": "RRP15-like protein", "gene_name": "Rrp15", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAAVQDSRVSPGEILKRSPKKKKKMKMVAKAAASKLEDEVKDSSDGEGSCDSEMDHSDDGAAEADSEDNVESCEEDNEDAAESSAGTNSGWADAMAKILNKKTPKSKATILTKNKELEKEKEKLKQERLEKRKQLDKKREWEMLCRVKPDVVKDKEAERNLQRIATRGVVQLFNAVQKHQRNVGEKVKEAGGSVRKRAKLMSTVSKKDFISVLRGMDGTSRNSPAGKSPKARQTEVKSEESPGWKILRDDFMMGASMKDWDKESEGEEPAGGRAEAAASR", "length": 281 }, "evidence": [ { "id": "A0A8V0YN72", "url": "https://omabrowser.org/oma/group/A0A8V0YN72/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9Y3B9-1", "protein_name": "RRP15-like protein", "gene_name": "RRP15", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAAAPDSRVSEEENLKKTPKKKMKMVTGAVASVLEDEATDTSDSEGSCGSEKDHFYSDDDAIEADSEGDAEPCDKENENDGESSVGTNMGWADAMAKVLNKKTPESKPTILVKNKKLEKEKEKLKQERLEKIKQRDKRLEWEMMCRVKPDVVQDKETERNLQRIATRGVVQLFNAVQKHQKNVDEKVKEAGSSMRKRAKLISTVSKKDFISVLRGMDGSTNETASSRKKPKAKQTEVKSEEGPGWTILRDDFMMGASMKDWDKESDGPDDSRPESASDSDT", "length": 282 }, "evidence": [ { "id": "A0A8V0YN72", "url": "https://omabrowser.org/oma/group/A0A8V0YN72/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "preribosome, large subunit precursor", "id": "GO:0030687", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030687", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YN72", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN72" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "maturation of 5.8S rRNA", "id": "GO:0000460", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000460", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YN72", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN72" } ], "pmid": "" }, { "name": "maturation of LSU-rRNA", "id": "GO:0000470", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000470", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YN72", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN72" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 84, "end_pos": 86, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 84, "end_pos": 86 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YNC1-1", "uniprot_ac": "A0A8V0YNC1", "uniprot_id": "A0A8V0YNC1_CHICK", "mass": { "chemical_mass": 252077.0, "monoisotopic_mass": 252077.0 }, "refseq": {}, "gene_names": [ { "name": "CCDC162", "type": "recommended", "evidence": [ { "id": "A0A8V0YNC1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNC1" } ] } ], "protein_names": [ { "name": "DUF4549 domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A8V0YNC1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNC1/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNC1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNC1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CCDC162", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNC1", "locus": {} } ], "crossref": [ { "id": "IPR024957", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024957", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR025913", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025913", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029376", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029376", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040401", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040401", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051756", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051756", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR060517", "url": "https://www.ebi.ac.uk/interpro/entry/IPR060517", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YGU6", "url": "https://www.orthodb.org/?gene=A0A8V0YGU6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YGW4", "url": "https://www.orthodb.org/?gene=A0A8V0YGW4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YN19", "url": "https://www.orthodb.org/?gene=A0A8V0YN19", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YN73", "url": "https://www.orthodb.org/?gene=A0A8V0YN73", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YNC1", "url": "https://www.orthodb.org/?gene=A0A8V0YNC1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YQ21", "url": "https://www.orthodb.org/?gene=A0A8V0YQ21", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YQ35", "url": "https://www.orthodb.org/?gene=A0A8V0YQ35", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR19336", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19336", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19336:SF10", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19336:SF10", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR33331", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR33331", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR33331:SF13", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR33331:SF13", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF06657", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06657", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14073", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14073", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF15082", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15082", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF28523", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF28523", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YGU6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGU6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YGU6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGU6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YGW4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGW4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YGW4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGW4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YN19", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN19", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YN19-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN19-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YN73", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN73", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YN73-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN73-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YNC1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNC1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YNC1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNC1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQ21", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ21", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQ21-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ21-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQ35", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ35", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQ35-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ35-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDEVYHISSTEKVQQLERELAAQLAELKAQIEDNGVLQGTPNRAYSSVPIPKDATYFRKERERILKKVLQVAEAKPLVIQADIMQRELESCWRREHTAASLPLLLHQFFTDRITQLVQSKYLHMLRWKRFCTHSSVIEQLYPLYQKQVSHIMDEYNDAVQRAARLSVARENFLSGKKNPMSLVTQEDLMIYTQWLVCHLHSLKGIHCFLQVLQHLPVSHKLSVVDERCPDVIQDKWDKLRSAFDRNADVFNTDVFCCSTFLRNESCHKDTGFSLPCHSTETKELKAQLQLLLAHFDIDYNLKDLKDPADEMELFYLVVQKFRSIFCKQQTMRTFPVYDTEISRSENWGMSGPTRALKKRANWIPFIKIKPKVDPWQQKLLIKMKQWKKVDKMLDIHSKFVEVSDMERVMEGLQDHAAAVLKPHPLQSGSATCSHASGQQNYDHIWKEVYAFTERHQELNTEDDNKAMACSEEDAGDSNSRKLQGSYRKMNERGYGYMSTWQLLGLEEGPATANKEDAVTRGAYLSFLLLRHLRLRELKRVCLGILNYFRSVERSLTISIAGLNLKAGHLIPSTEDTSWISAAKGGTGASGGLHSQPYVHYTPADYKVHSTQFMEFAEVENHDDFHTHEDGYIHTQDQRGAYIIYDVALEDLKELENHLLLVASQYIEKDKSNVTCGKSSGSNILEWAHASVDRFAVLFDLWTCETALLEKKCQLLDVYLEVYQHALDPEERFALAQAITDIMHKHPRFDLELEYFVNVYKDECICLQLHLQLLRDIVNQQIDVQREYLPKIWRKGQKGGISEFGLPYNVITKQLVSLNTCCPASKNIYLLEFHPSLGLVCSIPKALECIYQKFYSICRPRTASRAIKLEKQMLQVVLDEWLTMEKPECFYSSQVQKDLFAEVLIEDPVLVQEIALSLLEMGANEGRKEGKARQLFVLDSFSMLLELITLRHRLIEVATESARLASLYKAFAMEAGFGEFHLYLRPVHFEFALHKEKADHLPPTFITSLLEDDSCVDRYIPSSLPLSIQEIDSHVGKFSFRTRDGVMQLLCPSGIKNMQLILACQVIQKNALLAAVQQASFCYLVQFTHSLDIKEGNVSLTSQSSSASGRNSVSGSQAEDQLLPAATPATSFSPGRSSYLHPAFHRPPEAFVSIQLEKLGPRDMMLNTFIHKKETLGSRMENPDEVLQLKRDIIAEYCLKMNQRVSQHALRGQLIAFYNSLRSLLDDFPVVRDKYFIIGLSQGKKEQELKENFAADPRSFHPRPRYLLSPDGCTFLNLWFIPHPTEVLIMFKMLPEKAALKALRLSLQIVGAFHDVVAYLLAFAQLGNSPSSFCALNPEPLTPDWGGTGRIGTELQEIQRMIDSLQNPQDPREVAQLLAAHRDIMFLQFDAAIRHRLRETFLSSGNVSAYQSLTDRIYHALPPLSNCVIPSVFAAQLRLPQLLDVQSCRTLMHFPWRTFLMDGGLFPVTINNTINLNYNMQLCLCDLNDADRRVAHGELAAMQFLMEDVLQNHNDSAVNDHADCQALLANSKQNSAEMTDPSANRLQSRKKTCKLLPSHHDPVTSYNLLKSFLVLWKQLEILKAEWGRLKLGTEDIDTVPLYKEFCEQYGMEILRPAMKAMARQMGIEEDFREPVTSTQHVLPPRGVSEIEMKVYQLQKLLESLEIHMIHDVQKKVKQEMTLVISERARQESSLPTELWKHKVMQENFSVVRPQIVETFVQRLMENYEGSDTEVTFKKSHLQQCLTVLGCDIMARERSNFETYSMFYENILQQLHRLLYQKEQELHAVEDGGNQNDMSLTQIAGLSHEMIMEITALRARLTDLEDENAGLKEKIREEVRDEYESLVRNLFGTCVHLKGKLDIYRLSIEQRVLEIISEVRREGVDNMIDLKKKFGSPETNDDLEEHLSKQEQLQVLRDENISLSKLVCKLRALSCWKHTTQKAQLSAKLRYAEKEALQNKKECLNAKMMAEQEVTSLQGQLTSARKALEKSQAENDKRKKQLHKQKQMLLEMEHQKTQEARKRQILSVAKAQNMEKVLEEMEEKKQKLKFLVKEAEKPSKTGQLQQKRPKTAMQQIRSQLTQEFSLNLEAFQNIDELPCQVYDLEAAVSQRNVTAGSAAQLQNNKIATFTQLEDYKQEPLNSDPRSSTVRRRNTQRPKTVPSRWKQSAADRLLPHLNEKSLPTVFTQLQEHRLLQK", "length": 2194, "header": "tr|A0A8V0YNC1-1|A0A8V0YNC1_CHICK Isoform 1 of DUF4549 domain-containing protein OS=Gallus gallus OX=9031 GN=CCDC162 PE=1 SV=1 CANONICAL=A0A8V0YNC1-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YGU6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNC1/entry#A0A8V0YGU6-1", "sequence": { "sequence": "MDSESKDSLIGSFLQPPAKMIPAPFVCGEPKKLAAAGDNGPSICYNQNVVAALRTLQEKIHRLELERPHAEENLYSLSVAAAQYKKALEHESFKNDTAHHKLMQQRKDVSVKLKAAQSRCSLLEKQLDYMRKMVESAELENKMILQQQLYSGLCFLTHLQKEKNQNQMELHAKLEKLDVLEEECLKLTATQRIAELQTEFEINRILMSSDSSKSELKKRSRKKKIPKKKNPITKEMHLPQFHVKAGVLPFVVGKSVSSSHSLSANVQSMLHIMKHRNPHISSQRQIQSTSGISGQTTLSKSVTSSSTVTRRPSDLLLGIQDELSQMRFEHQELLKQIQETQESKIHEDLEQRLNCLVKQMDSKREQISKLKKHQNSVQKLKRKTQKLKKEAARVKPKYGNQKEVKEIAVTVRESMSKSHAGQKSRSSLQLLKNVQKLQSILKKDDIVWEQ", "length": 450, "header": "tr|A0A8V0YGU6-1|A0A8V0YGU6_CHICK Computationally mapped isoform of Centrosomal protein 57kDa-like protein 1 OS=Gallus gallus OX=9031 GN=CCDC162 PE=3 SV=1 CANONICAL=A0A8V0YNC1-1" }, "locus": { "chromosome": "3", "start_pos": 66751902, "end_pos": 66741484, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034208.1", "url": "https://www.ensembl.org/id/ENSGALT00010034208.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020095.1", "url": "https://www.ensembl.org/id/ENSGALP00010020095.1" } ] } }, { "isoform_ac": "A0A8V0YGW4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNC1/entry#A0A8V0YGW4-1", "sequence": { "sequence": "MDSESKDSLIGSFLQPPAKMIPAPFVCGEPKKLAAAGDNGPSICYNQNVVAALRTLQEKIHRLELERPHAEENLYSLSVAAAQYKKALEHESFKNDTAHHKLMQQRKDVSVKLKAAQSRCSLLEKQLDYMRKMVESAELENKMILQQQKEKNQNQMELHAKLEKLDVLEEECLKLTATQRIAEDKIKHLEEKLCKEEHHYKLIQGKAAQLQTEFEINRILMSSDSSKSELKKRSRKKKIPKKKNPITKEMHLPQFHVKAGVLPFVVGKSVSSSHSLSANVQSMLHIMKHRNPHISSQRQIQSTSGISGQTTLSKSVTSSSTVTRRPSDLLLGIQDELSQMRFEHQELLKQIQETQESKIHEDLEQRLNCLVKQMDSKREQISKLKKHQNSVQKLKRKTQKLKKEAARVKPKYEFTGDLFLRRTNMDEVYHISSTEKVQQLERELAAQLAELKAQIEDNGVLQGTPNRAYSSVPIPKDATYFRKERERILKKVLQVAEAKPLVIQADIMQRELESCWRREHTAASLPLLLHQFFTDRITQLVQSKYLHMLRWKRFCTHSSVIEQLYPLYQVGSQTPTSNAF", "length": 580, "header": "tr|A0A8V0YGW4-1|A0A8V0YGW4_CHICK Computationally mapped isoform of Centrosomal protein 57kDa-like protein 1 OS=Gallus gallus OX=9031 GN=CCDC162 PE=3 SV=1 CANONICAL=A0A8V0YNC1-1" }, "locus": { "chromosome": "3", "start_pos": 66751902, "end_pos": 66731818, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034228.1", "url": "https://www.ensembl.org/id/ENSGALT00010034228.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020110.1", "url": "https://www.ensembl.org/id/ENSGALP00010020110.1" } ] } }, { "isoform_ac": "A0A8V0YN19-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNC1/entry#A0A8V0YN19-1", "sequence": { "sequence": "MLDTGCSQNNNAVCLQLYLFILAMDSESKDSLIGSFLQPPAKMIPAPFVCGEPKKLAAAGDNGPSICYNQNVVAALRTLQEKIHRLELERPHAEENLYSLSVAAAQYKKALEHESFKNDTAHHKLMQQRKDVSVKLKAAQSRCSLLEKQLDYMRKMVESAELENKMILQQQKEKNQNQMELHAKLEKLDVLEEECLKLTATQRIAEDKIKHLEEKLCKEEHHYKLIQGKAAQLQTEFEINRILMSSDSSKSELKKRSRKKKIPKKKNPITKEMHLPQFHVKAGVLPFVVGKSVSSSHSLSANVQSMLHIMKHRNPHISSQRQIQSTSGISGQTTLSKSVTSSSTVTRRPSDLLLGIQDELSQMRFEHQELLKQIQETQESKIHEDLEQRLNCLVKQMDSKREQISKLKKHQNSVQKLKRKTQKLKKEAARVKPKYGNQKEVKEIAVTVRESMSKSHAGQKSRSSLQLLKNVQKLQSILKKDDIVWEQ", "length": 487, "header": "tr|A0A8V0YN19-1|A0A8V0YN19_CHICK Computationally mapped isoform of Centrosomal protein 57kDa-like protein 1 OS=Gallus gallus OX=9031 GN=CCDC162 PE=3 SV=1 CANONICAL=A0A8V0YNC1-1" }, "locus": { "chromosome": "3", "start_pos": 66756367, "end_pos": 66741484, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034215.1", "url": "https://www.ensembl.org/id/ENSGALT00010034215.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020099.1", "url": "https://www.ensembl.org/id/ENSGALP00010020099.1" } ] } }, { "isoform_ac": "A0A8V0YN73-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNC1/entry#A0A8V0YN73-1", "sequence": { "sequence": "MACSEEDAGDSNSRKLQGSYRKMNERGYGYMSTWQLLGLEEGPATANKEDAVTRGAYLSFLLLRHLRLRELKRVCLGILNYFRSVERSLTISIAGLNLKAGHLIPSTEDTSWISAAKGGTGASGGLHSQPYVHYTPADYKVHSTQFMEFAEVENHDDFHTHEDGYIHTQDQRGAYIIYDVALEDLKELENHLLLVASQYIEKDKSNVTCGKSSGSNILEWAHASVDRFAVLFDLWTCETALLEKKCQIDVQREYLPKIWRKGQKGGISEFGLPYNVITKQLVSLNTCCPASKNIYLLEFHPSLGLVCSIPKALECIYQKFYSICRPRTASRAIKLEKQMLQVVLDEWLTMEKPECFYSSQVQKDLFAEVLIEDPVLVQEIALSLLEMGANEGRKEGKARQLFVLDSFSMLLELITLRHRLIEVATESARLASLYKAFAMEAGFGEFHLYLRPVHFEFALHKEKADHLPPTFITSLLEDDSCVDRYIPSSLPLSIQEIDSHVGKFSFRTRDGVMQLLCPSGIKNMQLILACQVIQKNALLAAVQQASFCYLVQFTHSLDIKEGNVSLTSQSSSASGRNSVSGSQAEDQLLPAATPATSFSPGRSSYLHPAFHRPPEAFVSIQLEKLGPRDMMLNTFIHKKETLGSRMENPDEVLQLKRDIIAEYCLKMNQRVSQHALRGQLIAFYNSLRSLLDDFPVVRDKYFIIGLSQGKKEQELKENFAADPRSFHPRPRYLLSPDGCTFLNLWFIPHPTEVLIMFKMLPEKAALKALRLSLQIVGAFHDVVAYLLAFAQLGNSPSSFCALNPEPLTPDWGGTGRIGTELQEIQRMIDSLQNPQDPREVAQLLAAHRDIMFLQFDAAIRHRLRETFLSSGNVSAYQSLTDRIYHALPPLSNCVIPSVFAAQLRLPQLLDVQSCRTLMHFPWRTFLMDGGLFPVTINNTINLNYNMQLCLCDLNDADRRVAHGELAAMQFLMEDVLQNHNDSAVNDHADCQALLANSKQQNSAEMTDPSANRLQSRKKTCKLLPSHHDPVTSYNLLKSFLVLWKQLEILKAEWGRLKLGTEDIDTVPLYKEFCEQYGMEILRPAMKAMARQMGIEEDFREPVTSTQHVLPPRGVSEIEMKVYQLQKLLESLEIHMIHDVQKKVKQEMTLVISERARQESSLPTELWKHKVMQENFSVVRPQIVETFVQRLMENYEGSDTEVTFKKSHLQQCLTVLGCDIMARERSNFETYSMFYENILQQLHRLLYQKEQELHAVEDGGNQNDMSLTQIAGLSHEMIMEITALRARLTDLEDENAGLKEKIREEVRDEYESLVRNLFGTCVHLKGKLDIYRLSIEQRVLEIISEVRREGVDNMIDLKKKFGSPETNDDLEEHLSKEALQNKKECLNAKMMAEQEVTSLQGQLTSARKALEKSQAENDKRKKQLHKQKQMLLEMEHQKTQEARKRQILSVAKAQNMEKVLEEMEEKKQKLKFLVKEAEKPSKTGQLQQKRPKTAMQQIRSQLTQEFSLNLEAFQNIDELPCQVYDLEAAVSQRNVTAGSAAQLQNNKIATFTQLEDYKQEPLNSDPRSSTVRRRNTQRPKTVPSRWKQSAADRLLPHLNEKSLPTVFTQLQEHRLLQK", "length": 1617, "header": "tr|A0A8V0YN73-1|A0A8V0YNC1_CHICK Computationally mapped isoform of DUF4549 domain-containing protein OS=Gallus gallus OX=9031 GN=CCDC162 PE=1 SV=1 CANONICAL=A0A8V0YNC1-1" }, "locus": { "chromosome": "3", "start_pos": 66718826, "end_pos": 66650458, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034278.1", "url": "https://www.ensembl.org/id/ENSGALT00010034278.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020139.1", "url": "https://www.ensembl.org/id/ENSGALP00010020139.1" } ] } }, { "isoform_ac": "A0A8V0YNC1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNC1/entry#A0A8V0YNC1-1", "sequence": { "sequence": "MDEVYHISSTEKVQQLERELAAQLAELKAQIEDNGVLQGTPNRAYSSVPIPKDATYFRKERERILKKVLQVAEAKPLVIQADIMQRELESCWRREHTAASLPLLLHQFFTDRITQLVQSKYLHMLRWKRFCTHSSVIEQLYPLYQKQVSHIMDEYNDAVQRAARLSVARENFLSGKKNPMSLVTQEDLMIYTQWLVCHLHSLKGIHCFLQVLQHLPVSHKLSVVDERCPDVIQDKWDKLRSAFDRNADVFNTDVFCCSTFLRNESCHKDTGFSLPCHSTETKELKAQLQLLLAHFDIDYNLKDLKDPADEMELFYLVVQKFRSIFCKQQTMRTFPVYDTEISRSENWGMSGPTRALKKRANWIPFIKIKPKVDPWQQKLLIKMKQWKKVDKMLDIHSKFVEVSDMERVMEGLQDHAAAVLKPHPLQSGSATCSHASGQQNYDHIWKEVYAFTERHQELNTEDDNKAMACSEEDAGDSNSRKLQGSYRKMNERGYGYMSTWQLLGLEEGPATANKEDAVTRGAYLSFLLLRHLRLRELKRVCLGILNYFRSVERSLTISIAGLNLKAGHLIPSTEDTSWISAAKGGTGASGGLHSQPYVHYTPADYKVHSTQFMEFAEVENHDDFHTHEDGYIHTQDQRGAYIIYDVALEDLKELENHLLLVASQYIEKDKSNVTCGKSSGSNILEWAHASVDRFAVLFDLWTCETALLEKKCQLLDVYLEVYQHALDPEERFALAQAITDIMHKHPRFDLELEYFVNVYKDECICLQLHLQLLRDIVNQQIDVQREYLPKIWRKGQKGGISEFGLPYNVITKQLVSLNTCCPASKNIYLLEFHPSLGLVCSIPKALECIYQKFYSICRPRTASRAIKLEKQMLQVVLDEWLTMEKPECFYSSQVQKDLFAEVLIEDPVLVQEIALSLLEMGANEGRKEGKARQLFVLDSFSMLLELITLRHRLIEVATESARLASLYKAFAMEAGFGEFHLYLRPVHFEFALHKEKADHLPPTFITSLLEDDSCVDRYIPSSLPLSIQEIDSHVGKFSFRTRDGVMQLLCPSGIKNMQLILACQVIQKNALLAAVQQASFCYLVQFTHSLDIKEGNVSLTSQSSSASGRNSVSGSQAEDQLLPAATPATSFSPGRSSYLHPAFHRPPEAFVSIQLEKLGPRDMMLNTFIHKKETLGSRMENPDEVLQLKRDIIAEYCLKMNQRVSQHALRGQLIAFYNSLRSLLDDFPVVRDKYFIIGLSQGKKEQELKENFAADPRSFHPRPRYLLSPDGCTFLNLWFIPHPTEVLIMFKMLPEKAALKALRLSLQIVGAFHDVVAYLLAFAQLGNSPSSFCALNPEPLTPDWGGTGRIGTELQEIQRMIDSLQNPQDPREVAQLLAAHRDIMFLQFDAAIRHRLRETFLSSGNVSAYQSLTDRIYHALPPLSNCVIPSVFAAQLRLPQLLDVQSCRTLMHFPWRTFLMDGGLFPVTINNTINLNYNMQLCLCDLNDADRRVAHGELAAMQFLMEDVLQNHNDSAVNDHADCQALLANSKQNSAEMTDPSANRLQSRKKTCKLLPSHHDPVTSYNLLKSFLVLWKQLEILKAEWGRLKLGTEDIDTVPLYKEFCEQYGMEILRPAMKAMARQMGIEEDFREPVTSTQHVLPPRGVSEIEMKVYQLQKLLESLEIHMIHDVQKKVKQEMTLVISERARQESSLPTELWKHKVMQENFSVVRPQIVETFVQRLMENYEGSDTEVTFKKSHLQQCLTVLGCDIMARERSNFETYSMFYENILQQLHRLLYQKEQELHAVEDGGNQNDMSLTQIAGLSHEMIMEITALRARLTDLEDENAGLKEKIREEVRDEYESLVRNLFGTCVHLKGKLDIYRLSIEQRVLEIISEVRREGVDNMIDLKKKFGSPETNDDLEEHLSKQEQLQVLRDENISLSKLVCKLRALSCWKHTTQKAQLSAKLRYAEKEALQNKKECLNAKMMAEQEVTSLQGQLTSARKALEKSQAENDKRKKQLHKQKQMLLEMEHQKTQEARKRQILSVAKAQNMEKVLEEMEEKKQKLKFLVKEAEKPSKTGQLQQKRPKTAMQQIRSQLTQEFSLNLEAFQNIDELPCQVYDLEAAVSQRNVTAGSAAQLQNNKIATFTQLEDYKQEPLNSDPRSSTVRRRNTQRPKTVPSRWKQSAADRLLPHLNEKSLPTVFTQLQEHRLLQK", "length": 2194, "header": "tr|A0A8V0YNC1-1|A0A8V0YNC1_CHICK Isoform 1 of DUF4549 domain-containing protein OS=Gallus gallus OX=9031 GN=CCDC162 PE=1 SV=1 CANONICAL=A0A8V0YNC1-1" }, "locus": { "chromosome": "3", "start_pos": 66734818, "end_pos": 66650458, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034275.1", "url": "https://www.ensembl.org/id/ENSGALT00010034275.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020137.1", "url": "https://www.ensembl.org/id/ENSGALP00010020137.1" } ] } }, { "isoform_ac": "A0A8V0YQ21-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNC1/entry#A0A8V0YQ21-1", "sequence": { "sequence": "MCLVFPMAMDSESKDSLIGSFLQPPAKMIPAPFVCGEPKKLAAAGDNGPSICYNQNVVAALRTLQEKIHRLELERPHAEENLYSLSVAAAQYKKALEHESFKNDTAHHKLMQQRKDVSVKLKAAQSRCSLLEKQLDYMRKMVESAELENKMILQQQKEKNQNQMELHAKLEKLDVLEEECLKLTATQRIAEDKIKHLEEKLCKEEHHYKLIQGKAAQLQTEFEINRILMSSDSSKSELKKRSRKKKIPKKKNPITKEMHLPQFHVKAGVLPFVVGKSVSSSHSLSANVQSMLHIMKHRNPHISSQRQIQSTSGISGQTTLSKSVTSSSTVTRRPSDLLLGIQDELSQMRFEHQELLKQIQETQESKIHEDLEQRLNCLVKQMDSKREQISKLKKHQNSVQKLKRKTQKLKKEAARVKPKYGNQKEVKEIAVTVRESMSKSHAGQKSRSSLQLLKNVQKLQSILKKDDIVWEQ", "length": 472, "header": "tr|A0A8V0YQ21-1|A0A8V0YQ21_CHICK Computationally mapped isoform of Centrosomal protein 57kDa-like protein 1 OS=Gallus gallus OX=9031 GN=CCDC162 PE=3 SV=1 CANONICAL=A0A8V0YNC1-1" }, "locus": { "chromosome": "3", "start_pos": 66762773, "end_pos": 66741484, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034241.1", "url": "https://www.ensembl.org/id/ENSGALT00010034241.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020118.1", "url": "https://www.ensembl.org/id/ENSGALP00010020118.1" } ] } }, { "isoform_ac": "A0A8V0YQ35-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNC1/entry#A0A8V0YQ35-1", "sequence": { "sequence": "MACSEEDAGDSNSRKLQGSYRKMNERGYGYMSTWQLLGLEEGPATANKEDAVTRGAYLSFLLLRHLRLRELKRVCLGILNYFRSVERSLTISIAGLNLKAGHLIPSTEDTSWISAAKGGTGASGGLHSQPYVHYTPADYKVHSTQFMEFAEVENHDDFHTHEDGYIHTQDQRGAYIIYDVALEDLKELENHLLLVASQYIEKDKSNVTCGKSSGSNILEWAHASVDRFAVLFDLWTCETALLEKKCQLLDVYLEVYQHALDPEERFALAQAITDIMHKHPRFDLELEYFVNVYKDECICLQLHLQLLRDIVNQQIDVQREYLPKIWRKGQKGGISEFGLPYNVITKQLVSLNTCCPASKNIYLLEFHPSLGLVCSIPKALECIYQKFYSICRPRTASRAIKLEKQMLQVVLDEWLTMEKPECFYSSQVQKDLFAEVLIEDPVLVQEIALSLLEMGANEGRKEGKARQLFVLDSFSMLLELITLRHRLIEVATESARLASLYKAFAMEAGFGEFHLYLRPVHFEFALHKEKADHLPPTFITSLLEDDSCVDRYIPSSLPLSIQEIDSHVGKFSFRTRDGVMQLLCPSGIKNMQLILACQVIQKNALLAAVQQASFCYLVQFTHSLDIKEGNVSLTSQSSSASGRNSVSGSQAEDQLLPAATPATSFSPGRSSYLHPAFHRPPEAFVSIQLEKLGPRDMMLNTFIHKKETLGSRMENPDEVLQLKRDIIAEYCLKMNQRVSQHALRGQLIAFYNSLRSLLDDFPVVRDKYFIIGLSQGKKEQELKENFAADPRSFHPRPRYLLSPDGCTFLNLWFIPHPTEVLIMFKMLPEKAALKALRLSLQIVGAFHDVVAYLLAFAQLGNSPSSFCALNPEPLTPDWGGTGRIGTELQEIQRMIDSLQNPQDPREVAQLLAAHRDIMFLQFDAAIRHRLRETFLSSGNVSAYQSLTDRIYHALPPLSNCVIPSVFAAQLRLPQLLDVQSCRTLMHFPWRTFLMDGGLFPVTINNTINLNYNMQLCLCDLNDADRRVAHGELAAMQFLMEDVLQNHNDSAVNDHADCQALLANSKQQNSAEMTDPSANRLQSRKKTCKLLPSHHDPVTSYNLLKSFLVLWKQLEILKAEWGRLKLGTEDIDTVPLYKEFCEQYGMEILRPAMKAMARQMGIEEDFREPVTSTQHVLPPRGVSEIEMKVYQLQKLLESLEIHMIHDVQKKVKQEMTLVISERARQESSLPTELWKHKVMQENFSVVRPQIVETFVQRLMENYEGSDTEVTFKKSHLQQCLTVLGCDIMARERSNFETYSMFYENILQQLHRLLYQKEQELHAVEDGGNQNDMSLTQIAGLSHEMIMEITALRARLTDLEDENAGLKEKIREEVRDEYESLVRNLFGTCVHLKGKLDIYRLSIEQRVLEIISEVRREGVDNMIDLKKKFGSPETNDDLEEHLSKEALQNKKECLNAKMMAEQEVTSLQGQLTSARKALEKSQAENDKRKKQLHKQKQMLLEMEHQKTQEARKRQILSVAKAQNMEKVLEEMEEKKQKLKFLVKEAEKPSKTGQLQQKRPKTAMQQIRSQLTQEFSLNLEAFQNIDELPCQVYDLEAAVSQRNVTAGSAAQLQNNKIATFTQLEDYKQEPLNSDPRSSTVRRRNTQRPKTVPSRWKQSAADRLLPHLNEKSLPTVFTQLQEHRLLQK", "length": 1684, "header": "tr|A0A8V0YQ35-1|A0A8V0YQ35_CHICK Computationally mapped isoform of CCDC162 middle domain-containing protein OS=Gallus gallus OX=9031 GN=CCDC162 PE=1 SV=1 CANONICAL=A0A8V0YNC1-1" }, "locus": { "chromosome": "3", "start_pos": 66718826, "end_pos": 66650458, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034265.1", "url": "https://www.ensembl.org/id/ENSGALT00010034265.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020133.1", "url": "https://www.ensembl.org/id/ENSGALP00010020133.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1126, "start_aa": "Thr", "end_pos": 1126, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1126", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 2112, "start_aa": "Thr", "end_pos": 2112, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr2112", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNC1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNC1" } ], "pmid": "" }, { "name": "microtubule", "id": "GO:0005874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005874", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNC1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNC1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "microtubule binding", "id": "GO:0008017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008017", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNC1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNC1" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNC1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNC1" } ], "pmid": "" }, { "name": "gamma-tubulin binding", "id": "GO:0043015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043015", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNC1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNC1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1096, "end_pos": 1098, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1405, "end_pos": 1407, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1470, "end_pos": 1472, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1513, "end_pos": 1515, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1706, "end_pos": 1708, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1918, "end_pos": 1920, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2110, "end_pos": 2112, "annotation": "n_glycosylation_sequon" }, { "start_pos": 263, "end_pos": 265, "annotation": "n_glycosylation_sequon" }, { "start_pos": 672, "end_pos": 674, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YNC1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNC1" }, { "id": "PF28523", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF28523" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CCDC162 middle", "eco_id": "ECO_0000259", "start_pos": 1601, "end_pos": 1686, "start_aa": "Tyr", "end_aa": "Arg", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0YNC1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNC1" }, { "id": "PF15082", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15082" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "DUF4549", "eco_id": "ECO_0000259", "start_pos": 4, "end_pos": 145, "start_aa": "Val", "end_aa": "Gln", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 1126, 2112 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1096, "end_pos": 1098 }, { "start_pos": 1405, "end_pos": 1407 }, { "start_pos": 1470, "end_pos": 1472 }, { "start_pos": 1513, "end_pos": 1515 }, { "start_pos": 1706, "end_pos": 1708 }, { "start_pos": 1918, "end_pos": 1920 }, { "start_pos": 2110, "end_pos": 2112 }, { "start_pos": 263, "end_pos": 265 }, { "start_pos": 672, "end_pos": 674 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YN82-1", "uniprot_ac": "A0A8V0YN82", "uniprot_id": "A0A8V0YN82_CHICK", "mass": { "chemical_mass": 86834.0, "monoisotopic_mass": 86834.0 }, "refseq": {}, "gene_names": [ { "name": "CENPI", "type": "recommended", "evidence": [ { "id": "A0A8V0YN82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN82" } ] } ], "protein_names": [ { "name": "Centromere protein I", "type": "synonym", "evidence": [ { "id": "A0A8V0YN82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN82/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YN82", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN82" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CENPI", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN82", "locus": { "chromosome": "4", "start_pos": 2035207, "end_pos": 2052303, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010016129", "url": "https://www.ensembl.org/id/ENSGALG00010016129" } ] } } ], "crossref": [ { "id": "A0A8V0YN82", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YN82", "database": "AlphaFoldDB", "categories": [] }, { "id": "395207", "url": "https://www.ncbi.nlm.nih.gov/gene/395207", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR012485", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012485", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:395207", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:395207", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "RVFKNYY", "url": "https://omabrowser.org/oma/group/RVFKNYY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YN77", "url": "https://www.orthodb.org/?gene=A0A8V0YN77", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YN82", "url": "https://www.orthodb.org/?gene=A0A8V0YN82", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YUL2", "url": "https://www.orthodb.org/?gene=A0A8V0YUL2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YV09", "url": "https://www.orthodb.org/?gene=A0A8V0YV09", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YWM9", "url": "https://www.orthodb.org/?gene=A0A8V0YWM9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z1D2", "url": "https://www.orthodb.org/?gene=A0A8V0Z1D2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48208", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48208", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR48208:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48208:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07778", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07778", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-141430", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-141430", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-141444", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-141444", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-2467813", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2467813", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-2500257", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2500257", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-5663220", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5663220", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-606279", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-606279", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9648025", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9648025", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_989863", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989863", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YN77", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN77", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YN77-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN77-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YN82", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN82", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YN82-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN82-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YUL2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUL2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YUL2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUL2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YV09", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YV09", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YV09-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YV09-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YWM9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YWM9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YWM9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YWM9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z1D2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1D2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z1D2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1D2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQRRQSSKHSKRPLQVHHSNQTDLSAWRKGGTVDTEKSAQNRQSLSDQKNDNEQDSLEQALSYFEKIQDRVSLKKSEVLQKHLSTMESIALKRGLPPEGFDVLLDVALSGKLADTVNTRLLKSLIPASAIPESSIVSSVSWFCVSKCSSNIQLLFLRWLITMFDFIDHKEQVHALYGIFFSFLNDEKLCPYICHVLYLLTRKENVKPFRVRRLLDLQSKMGMQPHLQALLSLYKLFCPELVSITLPQKMKTYFKNADGPWKAAINAVRQRNQANSTVPQPLLLGTAQPHSRKRKWNTQLIVPASSANAQNLVVGGKMSRADSCSANESFPVEQLRTFPQLLQNIHRLEFPSQMGSVLTNPLLLHYMNCSKDESVYLRLYYWMGQTLQEECTWCVVDNNQYEEEFRGFLETVYKAECFLQEGFPSCEEFLYRSLPLWDGVSCRSQILQLVSWIPLSTFSEMKSQLCDPLAQLFFTSSLYFKCSVLESLKELLQNWLNWHVVQLDSESDSQFSSLNTTLSGLVNGVAELINFVGRISTAALHLEKSHTFLLYFILDFYETVCDIYLKYKLPLLIMPPAGVFYPALLSMDSVNLNQLCYIMYRYRTNLIAAKENEMSKKKIQQFKFSSQTYQEYNQYIIAMVGCLWTSSAFQKDNHPEGIRLDDELLKKTGVREYKNSFNIVYHPALMCYAVDFLQQAWPDDTTFNFNLIKGKKWNWYLRYLYGQGLEGLKLFIESSINRVSKASQSKAEDEDEKV", "length": 753, "header": "tr|A0A8V0YN82-1|A0A8V0YN82_CHICK Isoform 1 of Centromere protein I OS=Gallus gallus OX=9031 GN=CENPI PE=3 SV=1 CANONICAL=A0A8V0YN82-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YN77-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN82/entry#A0A8V0YN77-1", "sequence": { "sequence": "MQRRQSSKHSKRPLQVHHSNQTDLSAWRKGGTVDTEKSAQNRQSLSDQKNDNEQDSLEQALSYFEKIQDRVSLKKSEVLQKHLSTMESIALKRGLPPEGFDVLLDVALSGKLADTVNTRLLKSLIPASAIPESSIVSSVSWFCVSKCSSNIQLLFLRWLITMFDFIDHKEQVHALYGIFFSFLNDEKLCPYICHVLYLLTRKENVKPFRVRRLLDLQSKMTYFKNADGPWKAAINAVRQRNQANSTVPQPLLLGTAQPHSRKRKWNTQLIVPASSANAQNLVVGGKMSRADSCSANESFPVEQLRTFPQLLQNIHRLEFPSQMGSVLTNPLLLHYMNCSKDESVYLRLYYWMGQTLQEECTWCVVDNNQYEEEFRGFLETVYKAECFLQEGFPSCEEFLYRSLPLWDGVSCRSQILQLVSWIPLSTFSEMKSQLCDPLAQLFFTSSLYFKCSVLESLKELLQNWLNWHVVQLDSESDSQFSSLNTTLSGLVNGVAELINFVGRISTAALHLEKSHTFLLYFILDFYETVCDIYLKYKLPLLIMPPAGVFYPALLSMDSVNLNQLCYIMYRYRTNLIAAKENEMSKKKIQQFKFSSQTYQEYNQYIIAMVGCLWTSSAFQKDNHPEGIRLDDELLKKTGVREYKNSFNIVYHPALMCYAVDFLQQAWPDDTTFNFNLIKGKKWNWYLRYLYGQGLEGLKLFIESSINRVSKASQSKAEDEDEKV", "length": 723, "header": "tr|A0A8V0YN77-1|A0A8V0YN82_CHICK Computationally mapped isoform of Centromere protein I OS=Gallus gallus OX=9031 GN=CENPI PE=3 SV=1 CANONICAL=A0A8V0YN82-1" }, "locus": { "chromosome": "4", "start_pos": 2050810, "end_pos": 2037410, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010038816.1", "url": "https://www.ensembl.org/id/ENSGALT00010038816.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010022443.1", "url": "https://www.ensembl.org/id/ENSGALP00010022443.1" } ] } }, { "isoform_ac": "A0A8V0YN82-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN82/entry#A0A8V0YN82-1", "sequence": { "sequence": "MQRRQSSKHSKRPLQVHHSNQTDLSAWRKGGTVDTEKSAQNRQSLSDQKNDNEQDSLEQALSYFEKIQDRVSLKKSEVLQKHLSTMESIALKRGLPPEGFDVLLDVALSGKLADTVNTRLLKSLIPASAIPESSIVSSVSWFCVSKCSSNIQLLFLRWLITMFDFIDHKEQVHALYGIFFSFLNDEKLCPYICHVLYLLTRKENVKPFRVRRLLDLQSKMGMQPHLQALLSLYKLFCPELVSITLPQKMKTYFKNADGPWKAAINAVRQRNQANSTVPQPLLLGTAQPHSRKRKWNTQLIVPASSANAQNLVVGGKMSRADSCSANESFPVEQLRTFPQLLQNIHRLEFPSQMGSVLTNPLLLHYMNCSKDESVYLRLYYWMGQTLQEECTWCVVDNNQYEEEFRGFLETVYKAECFLQEGFPSCEEFLYRSLPLWDGVSCRSQILQLVSWIPLSTFSEMKSQLCDPLAQLFFTSSLYFKCSVLESLKELLQNWLNWHVVQLDSESDSQFSSLNTTLSGLVNGVAELINFVGRISTAALHLEKSHTFLLYFILDFYETVCDIYLKYKLPLLIMPPAGVFYPALLSMDSVNLNQLCYIMYRYRTNLIAAKENEMSKKKIQQFKFSSQTYQEYNQYIIAMVGCLWTSSAFQKDNHPEGIRLDDELLKKTGVREYKNSFNIVYHPALMCYAVDFLQQAWPDDTTFNFNLIKGKKWNWYLRYLYGQGLEGLKLFIESSINRVSKASQSKAEDEDEKV", "length": 753, "header": "tr|A0A8V0YN82-1|A0A8V0YN82_CHICK Isoform 1 of Centromere protein I OS=Gallus gallus OX=9031 GN=CENPI PE=3 SV=1 CANONICAL=A0A8V0YN82-1" }, "locus": { "chromosome": "4", "start_pos": 2050810, "end_pos": 2037410, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010038829.1", "url": "https://www.ensembl.org/id/ENSGALT00010038829.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010022448.1", "url": "https://www.ensembl.org/id/ENSGALP00010022448.1" } ] } }, { "isoform_ac": "A0A8V0YUL2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN82/entry#A0A8V0YUL2-1", "sequence": { "sequence": "MQRRQSSKHSKRPLQVHHSNQTDLSAWRKGGTVDTEKSAQNRQSLSDQKNDNEQDSLEQALSYFEKIQDRVSLKKSEVLQKHLSTMESIALKRGLPPEGFDVLLDVALSGKLADTVNTRLLKSLIPASAIPESSIVSSVSWFCVSKCSSNIQLLFLRWLITMFDFIDHKEQVHALYGIFFSFLNDEKLCPYICHGMQPHLQALLSLYKLFCPELVSITLPQKMKTYFKNADGPWKAAINAVRQRNQANSTVPQPLLLGTAQPHSRKRKWNTQLIVPASSANAQNLVVGGKMSRADSCSANESFPVEQLRTFPQLLQNIHRLEFPSQMGSVLTNPLLLHYMNCSKDESVYLRLYYWMGQTLQEECTWCVVDNNQYEEEFRGFLETVYKAECFLQEGFPSCEEFLYRSLPLWDGVSCRSQILQLVSWIPLSTFSEMKSQLCDPLAQLFFTSSLYFKCSVLESLKELLQNWLNWHVVQLDSESDSQFSSLNTTLSGLVNGVAELINFVGRISTAALHLEKSHTFLLYFILDFYETVCDIYLKYKLPLLIMPPAGVFYPALLSMDSVNLNQLCYIMYRYRTNLIAAKENEMSKKKIQQFKFSSQTYQEYNQYIIAMVGCLWTSSAFQKDNHPEGIRLDDELLKKTGVREYKNSFNIVYHPALMCYAVDFLQQVITKWCSDGKKWNWYLRYLYGQGLEGLKLFIESSINRVSKASQSKAEDEDEKV", "length": 721, "header": "tr|A0A8V0YUL2-1|A0A8V0YUL2_CHICK Computationally mapped isoform of Centromere protein I OS=Gallus gallus OX=9031 GN=CENPI PE=3 SV=1 CANONICAL=A0A8V0YN82-1" }, "locus": { "chromosome": "4", "start_pos": 2050810, "end_pos": 2037410, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010038790.1", "url": "https://www.ensembl.org/id/ENSGALT00010038790.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010022430.1", "url": "https://www.ensembl.org/id/ENSGALP00010022430.1" } ] } }, { "isoform_ac": "A0A8V0YV09-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN82/entry#A0A8V0YV09-1", "sequence": { "sequence": "MQRRQSSKHSKRPLQVHHSNQTDLSAWRKGGTVDTEKSAQNRQSLSDQKNDNEQDSLEQALSYFEKIQDRVSLKKSEVLQKHLSTMESIALKRGLPPEGFDVLLDVALSGKLADTVNTRLLKSLIPASAIPESSIVSSVSWFCVSKCSSNIQLLFLRWLITMFDFIDHKEQVHALYGIFFSFLNDEKLCPYICHVLYLLTRKENVKPFRVRRLLDLQSKMGMQPHLQALLSLYKLFCPELVSITLPQKMKTYFKNADGPWKAAINAVRQRNQANSTVPQPLLLGTAQPHSRKRKWNTQLIVPASSANAQNLVVGGKMSRADSCSANESFPVEQLRTFPQLLQNIHRLEFPSQMGSVLTNPLLLHYMNCSKDESVYLRLYYWMGQTLQEECTWCVVDNNQYEEEFRGFLETVYKAECFLQEGFPSCEEFLYRSLPLWDGVSCRSQILQLVSWIPLSTFSEMKSQLCDPLAQLFFTSSLYFKCSVLESLKELLQNWLNWHVVQLDSESDSQFSSLNTTLSGLVNGVAELINFVGRISTAALHLEKSHTFLLYFILDFYETVCDIYLKYKLPLLIMPPAGVFYPALLSMDSVNLNQLCYIMYRYRTNLIAAKENEMSKKKIQQFKFSSQTYQEYNQYIIAMVGCLWTSSAFQKDNHPEGIRLDDELLKKTGVREYKNSFNIVYHPALMCYAVDFLQQPLKVKQRMRMRKCDSRTCWSLSVIWNRETED", "length": 725, "header": "tr|A0A8V0YV09-1|A0A8V0YV09_CHICK Computationally mapped isoform of Centromere protein I OS=Gallus gallus OX=9031 GN=CENPI PE=3 SV=1 CANONICAL=A0A8V0YN82-1" }, "locus": { "chromosome": "4", "start_pos": 2050810, "end_pos": 2037355, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010038826.1", "url": "https://www.ensembl.org/id/ENSGALT00010038826.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010022447.1", "url": "https://www.ensembl.org/id/ENSGALP00010022447.1" } ] } }, { "isoform_ac": "A0A8V0YWM9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN82/entry#A0A8V0YWM9-1", "sequence": { "sequence": "MQRRQSSKHSKRPLQVHHSNQTDLSAWRKGGTVDTEKSAQNRQSLSDQKNDNEQDSLEQALSYFEKIQDRVSLKKSEVLQKHLSTMESIALKRGLPPEGFDVLLDVALSGKLADTVNTRLLKSLIPASAIPESSIVSSVSWFCVSKCSSNIQLLFLRWLITMFDFIDHKEQVHALYGIFFSFLNDEKLCPYICHVLYLLTRKENVKPFRVRRLLDLQSKMGMQPHLQALLSLYKLFCPELVSITLPQKMKTYFKNADGPWKAAINAVRQRNQANSTVPQPLLLGTAQPHSRKRKWNTQLIVPASSANAQNLVVGGKMSRADSCSANESFPVEQLRTFPQLLQNIHRLEFPSQMGSVLTNPLLLHYMNCSKDESVYLRLYYWMGQTLQEECTWCVVDNNQYEEEFRGFLETVYKAECFLQEGFPSCEEFLYRSLPLWDGVSCRSQILQLVSWIPLSTFSEMKSQLCDPLAQLFFTSSLYFKCSVLESLKELLQNWLNWHVVQLDSESDSQFSSLNTTLSGLVNGVAELINFVGRISTAALHLEKSHTFLLYFILDFYETVCDIYLKYKLPLLIMPPAGVFYPALLSMDSVNLNQLCYIMYRYRTNLIAAKENEMSKKKIQQFKFSSQTYQEYNQYIIAMVGCLWTSSAFQKDNHPEGIRLDDELLKKTGVREYKNSFNIVYHPALMCYAVDFLQQLAR", "length": 697, "header": "tr|A0A8V0YWM9-1|A0A8V0YWM9_CHICK Computationally mapped isoform of Centromere protein I OS=Gallus gallus OX=9031 GN=CENPI PE=3 SV=1 CANONICAL=A0A8V0YN82-1" }, "locus": { "chromosome": "4", "start_pos": 2050810, "end_pos": 2038211, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010038824.1", "url": "https://www.ensembl.org/id/ENSGALT00010038824.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010022446.1", "url": "https://www.ensembl.org/id/ENSGALP00010022446.1" } ] } }, { "isoform_ac": "A0A8V0Z1D2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN82/entry#A0A8V0Z1D2-1", "sequence": { "sequence": "MQRRQSSKHSKRPLQVHHSNQTDLSAWRKGGTVDTEKSAQNRQSLSDQKNDNEQDSLEQALSYFEKIQDRVSLKKSEVLQKHLSTMESIALKRGLPPEGFDVLLDVALSGKLADTVNTRLLKSLIPASAIPESSIVSSVSWFCVSKCSSNIQLLFLRWLITMFDFIDHKEQVHALYGIFFSFLNDEKLCPYICHVLYLLTRKENVKPFRVRRLLDLQSKMGMQPHLQALLSLYKLFCPELVSITLPQKMKTYFKNADGPWKAAINAVRQRNQANSTVPQPLLLGTAQPHSRKRKWNTQLIVPASSANAQNLVVGGKMSRADSCSANESFPVEQLRTFPQLLQNIHRLEFPSQMGSVLTNPLLLHYMNCSKDESVYLRLYYWMGQTLQEECTWCVVDNNQYEEEFRGFLETVYKAECFLQEGFPSCEEFLYRSLPLWDGVSCRSQILQLVSWIPLSTFSEMKSQLCDPLAQLFFTSSLYFKCSVLESLKELLQNWLNWHVVQLDSESDSQFSSLNTTLSGLVNGVAELINFVGRISTAALHLEKSHTFLLYFILDFYETVCDIYLKYKLPLLIMPPAGVFYPALLSMDSVNLNQLCYIMYRYRTNLIAAKENEMSKKKIQQFKFSSQTYQEYNQYIIAMVGCLWTSSAFQKDNHPEGIRLDDELLKKTGVREYKNSFNIVYHPALMCYAVDFLQQGLAR", "length": 698, "header": "tr|A0A8V0Z1D2-1|A0A8V0Z1D2_CHICK Computationally mapped isoform of Centromere protein I OS=Gallus gallus OX=9031 GN=CENPI PE=3 SV=1 CANONICAL=A0A8V0YN82-1" }, "locus": { "chromosome": "4", "start_pos": 2050810, "end_pos": 2038211, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010038807.1", "url": "https://www.ensembl.org/id/ENSGALT00010038807.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010022439.1", "url": "https://www.ensembl.org/id/ENSGALP00010022439.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:395207", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:395207", "resource": "KEGG Pathway" }, { "id": "R-GGA-141430", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-141430", "resource": "Reactome", "description": "Inactivation of APC/C via direct inhibition of the APC/C complex" }, { "id": "R-GGA-141444", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-141444", "resource": "Reactome", "description": "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" }, { "id": "R-GGA-2467813", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2467813", "resource": "Reactome", "description": "Separation of Sister Chromatids" }, { "id": "R-GGA-2500257", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2500257", "resource": "Reactome", "description": "Resolution of Sister Chromatid Cohesion" }, { "id": "R-GGA-5663220", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5663220", "resource": "Reactome", "description": "RHO GTPases Activate Formins" }, { "id": "R-GGA-606279", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-606279", "resource": "Reactome", "description": "Deposition of new CENPA-containing nucleosomes at the centromere" }, { "id": "R-GGA-9648025", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9648025", "resource": "Reactome", "description": "EML4 and NUDC in mitotic spindle formation" } ], "orthologs": [ { "uniprot_canonical_ac": "F1QJK1-1", "protein_name": "Centromere protein I", "gene_name": "cenpi", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAGLSNLTGLVSEPSGEAESSVSSVSNRSLRLAEKEKKKGEADPFTAAAKYLSQFKAGTTVRGNDELERSILVVETVAVSKGLPPEVITVLLDLALSLNAGTPNCSRILKFLIPATVVPQEAIVKGVSWLCVGKMPMNAQVLFLRWVLTVFDLIDCKDDLRSIYGFIFSFVTEETLCPFICHLLYLLTTREHVHPYRVRKLLDIQAKMGRQPFLTQLLALYKVFRPDLVTLSLPSRARTGFKNHNSTWKVALSAVQRKNKGAVLVDQSLSVDVKEKPSSRKRKRHHLAVPPLSSAFDSNSSKKGLRLQELRSFKELLENIHNIELPAQMGSMLGSTLALHYLDCVQDESAFLRLNFWLGHSLQEEFLLCPVDGSSDNTSEACRFLNTILFSQQFLQEGFSSTESFLYKFLSVWDGSLLRPQILDLLSDIPLMPSFYMNKLLFEPLKQLYFTSTVFFKCSVIECLNSMLVKWLTWHSVSASEGSLDISLNSNSTMTMTLSGFMDSVMELVRFVGLLASEGLRLENCHVLLLNQTLAFYETVCDMFLKYSLPLIIMPPAGVFYPALFAIDSISLDRLGYIMYRYRMNLTLAKQQKQQREQTFHISRNAYKEFNRNLQTMVNSMWNSQWCIPGSDLEINKDLIALSKIAEPWCCFDIIHHPALFSYAIEFHQRCWPERKDVDLGSIKTGKYWNWYMEFLFNQGFDGLNNFIRTNTGHGPSSSSQDDRQPLSQNCH", "length": 732 }, "evidence": [ { "id": "A0A8V0YN82", "url": "https://omabrowser.org/oma/group/A0A8V0YN82/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q63517-1", "protein_name": "Centromere protein I", "gene_name": "Cenpi", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MATPRLTRNSQQQNRISQGSNSRQTTLLDWKVKDKAGNSKSVLEESSSLEDSNHADDQTEDALQTAVEYFQKGPKKASLSKDSVLEKHLKTVENVAWNNGLAPEAIDILLNVALSGKFGNALSTRILKCMIPETHISEDSVVKAVSWLCVGKCSGNTKVLFYRWLVAMFDFIDHKKQINSLYGFFFVSLQDDTLCPYVCHLLYLLTKKENVKPFRARKLLDLQAKMGMQPHLQALLSLYKFFAPTLISVSLPVRKKIFFNNSKNLWTPALLAVKLRNQGIFPEPLKLQLGPTSGRSLKRKWNYHSVIPAVNSAKKECREKMSLFDYLSNDRSLPVEQLQSFPQLLENIHCLELPSQMSSVLNSSLLLHYVNCVKDESILLRLSYWLSQTLQEECVWYNMNDYQQEKEFINFLDMVIRVQCFLQEGFYSCEAFLYKSLPLWDGFSCRSQFLKLLAWIPFSSFSEIKPLLLDHLAPLFFTSSIYFKCSLLQCLKDLLQNWLLWLSTEAQVQPMTDSPLETTLGGSMDSVSQLIEYIGWLSMVAIRLESSSTLLVHFILDFYEKVCDIYINYDLPLVVLFPPVVFHSAFLSLDATILNQLCYIMYRYRDNLTAAKKKDLVQKAKSEFSISSKICKEFNYYLTALVHCLWSSRPFETGVYIDPQIIENTGETQYKHNLNFVHHPCLLNYAASFLLQESPEEMPVHLSSIRGKKWNWYLDHLYSEGFQGLNLFIKSSIDHSSVSKTEKNT", "length": 745 }, "evidence": [ { "id": "A0A8V0YN82", "url": "https://omabrowser.org/oma/group/A0A8V0YN82/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8K1K4-1", "protein_name": "Centromere protein I", "gene_name": "Cenpi", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MATQRVTRNSQQQNRISQGSNSRQTSLLDWMVKDKSGNFKSVLKESSSVEDSTRTDDRTEGALQVAVGYFQKGPKKASLSKDKVLEKHLTTVENVALSNGLAPEAIDILLNVALSGKFGNAVNSRILKCMIPESHISEDSVLKAVSWLCVDKCSGNTKVLFYRWLVAMFDFIDHKKQISSLYGFFFASLQDDTLCPYVCHLLYLLTKRENVKPFRVRKLLDLQAKMGMQPHLQALLSLYKFFAPTLISVSLPVRKKIFFNNSKNLWTSASLAVRLRNQGAFPEPLNLPLRPTTGRSLKRKWNSHSVIPALNSANKEYGEKTASLFDYLSSERSLPLEQLQRFPQLLESIHCLELPSQMCSVLNSPLLLHYINCVKDESILLRISYWLSQALQEECVWYNINNYEQEKEFINFLDLVIRVQCFLQEGFYSCEAFLYKSLPLWDGSSCRSQYLQLLAWIPFSSFSEVKPLLSDHLAPLFFTSSIYFKCSVLQSLQELLQNWLLWLSTDAHVQPTTDSPLETTLGGSMSSVSQLIEYTGWLCVVAMRLESSSTLLLHFILDFYEKVCDIYINYDLPIVVLFPPVIFHSALLSLDATILNQLCYIMYRYRNNWTAAKKNRYLQKAKPEFSLSSKICKEYNYYLTAMVCCLWTSRPFKAGVYTDPETIENTGGTQYKSTLNIVYHPSLLSYAASFLLQESPEEMTEHLSSIQGKKWNWYLDYLYSEGFQGLKLFIKSSVHSSVPKPEENTE", "length": 746 }, "evidence": [ { "id": "A0A8V0YN82", "url": "https://omabrowser.org/oma/group/A0A8V0YN82/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q92674-1", "protein_name": "Centromere protein I", "gene_name": "CENPI", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSPQKRVKNVQAQNRTSQGSSSFQTTLSAWKVKQDPSNSKNISKHGQNNPVGDYEHADDQAEEDALQMAVGYFEKGPIKASQNKDKTLEKHLKTVENVAWKNGLASEEIDILLNIALSGKFGNAVNTRILKCMIPATVISEDSVVKAVSWLCVGKCSGSTKVLFYRWLVAMFDFIDRKEQINLLYGFFFASLQDDALCPYVCHLLYLLTKKENVKPFRVRKLLDLQAKMGMQPHLQALLSLYKFFAPALISVSLPVRKKIYFKNSENLWKTALLAVKQRNRGPSPEPLKLMLGPANVRPLKRKWNSLSVIPVLNSSSYTKECGKKEMSLSDCLNRSGSFPLEQLQSFPQLLQNIHCLELPSQMGSVLNNSLLLHYINCVRDEPVLLRFYYWLSQTLQEECIWYKVNNYEHGKEFTNFLDTIIRAECFLQEGFYSCEAFLYKSLPLWDGLCCRSQFLQLVSWIPFSSFSEVKPLLFDHLAQLFFTSTIYFKCSVLQSLKELLQNWLLWLSMDIHMKPVTNSPLETTLGGSMNSVSKLIHYVGWLSTTAMRLESNNTFLLHFILDFYEKVCDIYINYNLPLVVLFPPGIFYSALLSLDTSILNQLCFIMHRYRKNLTAAKKNELVQKTKSEFNFSSKTYQEFNHYLTSMVGCLWTSKPFGKGIYIDPEILEKTGVAEYKNSLNVVHHPSFLSYAVSFLLQESPEERTVNVSSIRGKKWSWYLDYLFSQGLQGLKLFIRSSVHHSSIPRAEGINCNNQY", "length": 756 }, "evidence": [ { "id": "A0A8V0YN82", "url": "https://omabrowser.org/oma/group/A0A8V0YN82/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YN82", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN82" } ], "pmid": "" }, { "name": "kinetochore", "id": "GO:0000776", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000776", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YN82", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN82" } ], "pmid": "" }, { "name": "inner kinetochore", "id": "GO:0000939", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000939", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YN82", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN82" } ], "pmid": "" }, { "name": "nuclear body", "id": "GO:0016604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016604", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YN82", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN82" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "CENP-A containing chromatin assembly", "id": "GO:0034080", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034080", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YN82", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN82" } ], "pmid": "" }, { "name": "mitotic sister chromatid segregation", "id": "GO:0000070", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000070", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YN82", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN82" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 20, "end_pos": 22, "annotation": "n_glycosylation_sequon" }, { "start_pos": 274, "end_pos": 276, "annotation": "n_glycosylation_sequon" }, { "start_pos": 326, "end_pos": 328, "annotation": "n_glycosylation_sequon" }, { "start_pos": 367, "end_pos": 369, "annotation": "n_glycosylation_sequon" }, { "start_pos": 514, "end_pos": 516, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 20, "end_pos": 22 }, { "start_pos": 274, "end_pos": 276 }, { "start_pos": 326, "end_pos": 328 }, { "start_pos": 367, "end_pos": 369 }, { "start_pos": 514, "end_pos": 516 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YN80-1", "uniprot_ac": "A0A8V0YN80", "uniprot_id": "A0A8V0YN80_CHICK", "mass": { "chemical_mass": 79922.0, "monoisotopic_mass": 79922.0 }, "refseq": {}, "gene_names": [ { "name": "BCL6", "type": "recommended", "evidence": [ { "id": "A0A8V0YN80", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN80" } ] } ], "protein_names": [ { "name": "B-cell CLL/lymphoma 6", "type": "synonym", "evidence": [ { "id": "A0A8V0YN80", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN80/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YN80", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN80" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "BCL6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN80", "locus": { "chromosome": "9", "start_pos": 14495600, "end_pos": 14479373, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013635", "url": "https://www.ensembl.org/id/ENSGALG00010013635" } ] } } ], "crossref": [ { "id": "A0A8V0YN80", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YN80", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd18331", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18331", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "424912", "url": "https://www.ncbi.nlm.nih.gov/gene/424912", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000210", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000210", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011333", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011333", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "DARMPMA", "url": "https://omabrowser.org/oma/group/DARMPMA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YN80", "url": "https://www.orthodb.org/?gene=A0A8V0YN80", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YN89", "url": "https://www.orthodb.org/?gene=A0A8V0YN89", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24394", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24394", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24394:SF36", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24394:SF36", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00651", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00651", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-212436", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-212436", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YN80", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN80", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YN80-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN80-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YN89", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN89", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YN89-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN89-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASPADSCIQFTRHASDVLLNLNRLRSRDILTDVVIIVNREQFRAHKTVLMACSGLFYSIFTDQLKCNLNVINLDPEINPEGFCILLDFMYTSRLNLRENNIMAVMATALYLQMEHVVDTCRRFVKSSEAEMVSAVKTPREEFLAGRMLNHPEVMAYRGRDVSENSMPLQNGSLCNGRAFAPGLFNSLPGSSISYPGYSPLPLNGFLVDDELREMRMPLSELSRVSAFPKERIPCDGSRTIPTEYMRTITDISANMCHATIYSPKEGAAEEARSDMHYSVASGPKPVVPSIRNNPYFSCDKVAKEEERTSSEDEISQHFEPTNTPLDRKGLISPQSPQKSDCQPNSPTESSSSKNARISQNSNSLFTKSPTDPKACNWKKYKFIVLNSLNQSTKQDSADQNEMGTLSPRTYMPMSTCQQSMEPEHLNVQSPTKMSVNGEDSNIPQASRLNNIVNRSRDGSPRSSEGQSPLYMHSSKCSSCGCQSPQHTEMCLHTSGSAFGEEMGETQSEYSDSSCENGAFFCNECDCRFSEEASLKRHSLQVHSDKPYKCDRCQASFRYKGNLASHKTVHTGEKPYRCNICGAQFNRPANLKTHTRIHSGEKPYKCETCGARFVQVAHLRAHVLIHTGEKPYPCEICGTRFRHLQTLKSHLRIHTGEKPYHFSVCIYVQCGFARCLSFQWKFSMYGLYMELSFFFKVQPDVAEGVVVELSV", "length": 711, "header": "tr|A0A8V0YN80-1|A0A8V0YN80_CHICK Isoform 1 of B-cell CLL/lymphoma 6 OS=Gallus gallus OX=9031 GN=BCL6 PE=4 SV=1 CANONICAL=A0A8V0YN80-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YN80-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN80/entry#A0A8V0YN80-1", "sequence": { "sequence": "MASPADSCIQFTRHASDVLLNLNRLRSRDILTDVVIIVNREQFRAHKTVLMACSGLFYSIFTDQLKCNLNVINLDPEINPEGFCILLDFMYTSRLNLRENNIMAVMATALYLQMEHVVDTCRRFVKSSEAEMVSAVKTPREEFLAGRMLNHPEVMAYRGRDVSENSMPLQNGSLCNGRAFAPGLFNSLPGSSISYPGYSPLPLNGFLVDDELREMRMPLSELSRVSAFPKERIPCDGSRTIPTEYMRTITDISANMCHATIYSPKEGAAEEARSDMHYSVASGPKPVVPSIRNNPYFSCDKVAKEEERTSSEDEISQHFEPTNTPLDRKGLISPQSPQKSDCQPNSPTESSSSKNARISQNSNSLFTKSPTDPKACNWKKYKFIVLNSLNQSTKQDSADQNEMGTLSPRTYMPMSTCQQSMEPEHLNVQSPTKMSVNGEDSNIPQASRLNNIVNRSRDGSPRSSEGQSPLYMHSSKCSSCGCQSPQHTEMCLHTSGSAFGEEMGETQSEYSDSSCENGAFFCNECDCRFSEEASLKRHSLQVHSDKPYKCDRCQASFRYKGNLASHKTVHTGEKPYRCNICGAQFNRPANLKTHTRIHSGEKPYKCETCGARFVQVAHLRAHVLIHTGEKPYPCEICGTRFRHLQTLKSHLRIHTGEKPYHFSVCIYVQCGFARCLSFQWKFSMYGLYMELSFFFKVQPDVAEGVVVELSV", "length": 711, "header": "tr|A0A8V0YN80-1|A0A8V0YN80_CHICK Isoform 1 of B-cell CLL/lymphoma 6 OS=Gallus gallus OX=9031 GN=BCL6 PE=4 SV=1 CANONICAL=A0A8V0YN80-1" }, "locus": { "chromosome": "9", "start_pos": 14495393, "end_pos": 14488241, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032774.1", "url": "https://www.ensembl.org/id/ENSGALT00010032774.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019414.1", "url": "https://www.ensembl.org/id/ENSGALP00010019414.1" } ] } }, { "isoform_ac": "A0A8V0YN89-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN80/entry#A0A8V0YN89-1", "sequence": { "sequence": "MASPADSCIQFTRHASDVLLNLNRLRSRDILTDVVIIVNREQFRAHKTVLMACSGLFYSIFTDQLKCNLNVINLDPEINPEGFCILLDFMYTSRLNLRENNIMAVMATALYLQMEHVVDTCRRFVKSSEAEMVSAVKTPREEFLAGRMLNHPEVMAYRGRDVSENSMPLQNGSLCNGRAFAPGLFNSLPGSSISYPGYSPLPLNGFLVDDELREMRMPLSELSRVSAFPKERIPCDGSRTIPTEYMRTITDISANMCHATIYSPKEGAAEEARSDMHYSVASGPKPVVPSIRNNPYFSCDKVAKEEERTSSEDEISQHFEPTNTPLDRKGLISPQSPQKSDCQPNSPTESSSSKNARISQNSNSLFTKSPTDPKACNWKKYKFIVLNSLNQSTKQDSADQNEMGTLSPRTYMPMSTCQQSMEPEHLNVQSPTKMSVNGEDSNIPQASRLNNIVNRSRDGSPRSSEGQSPLYMHSSKCSSCGCQSPQHTEMCLHTSGSAFGEEMGETQSEYSDSSCENGAFFCNECDCRFSEEASLKRHSLQVHSDKPYKCDRCQASFRYKGNLASHKTVHTGEKPYRCNICGAQFNRPANLKTHTRIHSGEKPYKCETCGARFVQVAHLRAHVLIHTGEKPYPCEICGTRFRHLQTLKSHLRIHTGEKPYHCEKCNLHFRHKSQLRLHLRQKHGAITNTKVQYRISANEVPPELPKAC", "length": 708, "header": "tr|A0A8V0YN89-1|A0A8V0YN89_CHICK Computationally mapped isoform of B-cell CLL/lymphoma 6 OS=Gallus gallus OX=9031 GN=BCL6 PE=4 SV=1 CANONICAL=A0A8V0YN80-1" }, "locus": { "chromosome": "9", "start_pos": 14494306, "end_pos": 14488241, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032792.1", "url": "https://www.ensembl.org/id/ENSGALT00010032792.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019424.1", "url": "https://www.ensembl.org/id/ENSGALP00010019424.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-212436", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-212436", "resource": "Reactome", "description": "Generic Transcription Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287AXN0-1", "protein_name": "BCL6 transcription repressor", "gene_name": "BCL6", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MASPADSCIQFTRHASDVLLNLNRLRSRDILTDVVIVVSREQFRAHKTVLMACSGLFYSIFTDQLKCNLSVINLDPEINPEGFCILLDFMYTSRLNLREGNIMAVMATAMYLQMEHVVDTCRKFIKASEAEMVPAIKPPREEFLNSRMLMPQDIMAYRGREVVENSLPLRNAPGCESRAFAPSLYNGLSTPPASYPVYGHLPVSSFLFSDEELRDARMPVANPFPKERALPCDSARPIHADYSRPAMEISPSMCHSSIYSPKEAAPEEARSDMHYSVAEGPKPAAPSARGAPYFPCDKAGKEEERPSSEDEIALHFEPPNAPLNRKGLVSPQSPQKSDCQPNSPTESCSSKNACILQTSGSPPAKSPTDPKACNWKKYKFIVLNSLNQNAKPEGPEPAELGRLSPRAYTAPPACQPPMEPETLDLQSPTKLSTNGEDSTIPQASRLNNIVNRSLTGSPRSSSESHSPLYLHPPKCTSCGSQSPQHTEMCLHAAGPTFPEELGETQSEYSDSSCGEKPYRCNICGAQFNRPANLKTHTRIHSGEKPYKCETCGARFVQVAHLRAHVLIHTGEKPYPCEICGTRFRHLQTLKSHLRIHTGEKPYHCEKCNLHFRHKSQLRLHLRQKHGAITNTKVQYRVSATDLPPELPKAC", "length": 650 }, "evidence": [ { "id": "A0A8V0YN80", "url": "https://omabrowser.org/oma/group/A0A8V0YN80/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8M9PZK1-1", "protein_name": "BCL6A transcription repressor a isoform X1", "gene_name": "bcl6aa", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MPHSLQQKHAQQMLLLCQGINGTREDGPAPHSWSHKRSYSDLEKMACAADSCIQFTRHASDVLLNLNRLRSRDILTDVTILVNRQQFRAHKTVLMACSGLFYSIFTDSHKCNLNAISLDPKVDPEGFAILLEFMYTSRLALKESLIMAIMNTAIYLQMDHVVDTCHRFIKSSDSSIKLPREDFLVSPLLLPQDIHSYRPHEVMDNVSGRSATFRDGRPYGVCMFNGVNAPNNSYLYGQFPMQGFPFPLCKLTDTKNTFSDFSKGGIIHHKHCSPSDGNNPVLNDFTRSATSGSSAVCHTGSYSSRELGRDEDMKRETLEGVVHSIGMSSRKHGFISLAQEQQRESGKEQSSLAEEHLSHQHYSMGISSNGRKTLMSSPQSPLKSDCQPNSPTESSSSKNAALAQALQPPTSQGTSDPKARNWKKYKFIVLNQSSKEEETNPPDPGMHSPQRPGLSAFLHHVDSEHPDSKVTTKISEQGEDFPAPQASRLNNIINRSLEGSQRNIDSHSSLYMNHLKCSSCGSQSPQHSDVCPNTSASRLAEEMSEMHSEYSDSSCENGTYFCNECDSKFAEEEALKRHTLQVHSDKPYKCDRCQAAFRYKGNLASHKTVHTGEKPYRCNICGAQFNRPANLKTHTRIHSGEKPYKCETCGARFVQVAHLRAHVLIHTGEKPYPCEICGTRFRHLQTLKSHLRIHTGEKPYHCEKCNLHFRHKSQLRLHLRQKHGAITNTKIQYRMSSTELPTDLTKAC", "length": 748 }, "evidence": [ { "id": "A0A8V0YN80", "url": "https://omabrowser.org/oma/group/A0A8V0YN80/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "E1B8E6-1", "protein_name": "BCL6 transcription repressor", "gene_name": "BCL6", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MASPADSCIQFTRHASDVLLNLNRLRSRDILTDVVIVVSREQFRAHKTVLMACSGLFYSIFTDQLKCNLSVINLDPEINPEGFCILLDFMYTSRLNLREGNIMAVMATAMYLQMEHVVDTCRKFIKASEAEMVPAIKPPREDFLNSRMLMPQDIMAYRGREVVENSLPLRNAPGCESRAFAPSLYNGLSTPPASYPVYGHLPVSSFLFSDEELRDARMPIANPFPKDRALPCDSARPVPSEYSRPAMEISPSVCHSTIYSPKEAAPEEARSDMHYSVAEGPKPAAPSARSAPYFPCDKAGKEEERPSSEDEIALHFEPPNAPLNRKGLVSPQSPQKSDCQPNSPTESCSSKNACILQTSGSPPAKSPTDPKACNWKKYKFIVLNSLNQNAKPEGPEQAELGRLSPRAYAAPPACQPPMEPDSLDLQSPTKLSTSAEDSTIPQASRLNNIVNRSLTGSPRSSSESHSPLYLHPPKCTSCGSQSPQHAEMCLHAAGPTFPEELGETQSEYSDSSCGEKPYRCNICGAQFNRPANLKTHTRIHSGEKPYKCETCGARFVQVAHLRAHVLIHTGEKPYPCEICGTRFRHLQTLKSHLRIHTGEKPYHCEKCNLHFRHKSQLRLHLRQKHGAITNTKVQYRVSATDLPPELPKAC", "length": 650 }, "evidence": [ { "id": "A0A8V0YN80", "url": "https://omabrowser.org/oma/group/A0A8V0YN80/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "G3GT91-1", "protein_name": "B-cell lymphoma 6 protein isoform X1", "gene_name": "Bcl6", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MASPADSCIQFTRHASDVLLNLNRLRSRDILTDVVIVVSREQFRAHKTVLMACSGLFYSIFTDQLKCNLNVINLDPEINPEGFCILLDFMYTSRLNLREGNIMAVMATAMYLQMEHVVDTCRKFIKASEAEMVPALKPPREEFLNSRMLMPHDIMGYRGREVVENNLPLRNTPGCESRAFAPSLYSGLSTPPASYPMYSHLPLSSFLFADEEPRDAHARMPVANPFPKERTLSCDSARPVPSEYSRPAMEVSLSLCHSNIYLPKEAVPEDTRSDMHFSVTEGPKPAAPSARNAPYFPCDKASKEERPSSEDEIALHFEPPNAPLNRKGLVSPQSPQKSDCQPNSPTESCSSKNACILQASGSPPAKSPTDPKACNWKKYKFIVLNSLNQNAKPEGSEQTELGRLSPRAYPVQPAGQPPLEPDNLGLQIPTKLSASGEDSTIPQASRLNNIVNRSLTGSPRSSSESHSPLYMHPPKCTSCDSQSPQHTEMCLHTAGPTFPEEMGETQSEYSDSSCENGAFFCNECDCRFSEEASLKRHTLQTHSDKPYKCDRCQASFRYKGNLASHKTVHTGEKPYRCNICGAQFNRPANLKTHTRIHSGEKPYKCETCGARFVQVAHLRAHVLIHTGEKPYPCEICGTRFRHLQTLKSHLRIHTGEKPYHCEKCNLHFRHKSQLRLHLRQKHGAITNTKVQYRVSAADLPPELPKAC", "length": 707 }, "evidence": [ { "id": "A0A8V0YN80", "url": "https://omabrowser.org/oma/group/A0A8V0YN80/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P41182-1", "protein_name": "B-cell lymphoma 6 protein", "gene_name": "BCL6", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MASPADSCIQFTRHASDVLLNLNRLRSRDILTDVVIVVSREQFRAHKTVLMACSGLFYSIFTDQLKCNLSVINLDPEINPEGFCILLDFMYTSRLNLREGNIMAVMATAMYLQMEHVVDTCRKFIKASEAEMVSAIKPPREEFLNSRMLMPQDIMAYRGREVVENNLPLRSAPGCESRAFAPSLYSGLSTPPASYSMYSHLPVSSLLFSDEEFRDVRMPVANPFPKERALPCDSARPVPGEYSRPTLEVSPNVCHSNIYSPKETIPEEARSDMHYSVAEGLKPAAPSARNAPYFPCDKASKEEERPSSEDEIALHFEPPNAPLNRKGLVSPQSPQKSDCQPNSPTESCSSKNACILQASGSPPAKSPTDPKACNWKKYKFIVLNSLNQNAKPEGPEQAELGRLSPRAYTAPPACQPPMEPENLDLQSPTKLSASGEDSTIPQASRLNNIVNRSMTGSPRSSSESHSPLYMHPPKCTSCGSQSPQHAEMCLHTAGPTFPEEMGETQSEYSDSSCENGAFFCNECDCRFSEEASLKRHTLQTHSDKPYKCDRCQASFRYKGNLASHKTVHTGEKPYRCNICGAQFNRPANLKTHTRIHSGEKPYKCETCGARFVQVAHLRAHVLIHTGEKPYPCEICGTRFRHLQTLKSHLRIHTGEKPYHCEKCNLHFRHKSQLRLHLRQKHGAITNTKVQYRVSATDLPPELPKAC", "length": 706 }, "evidence": [ { "id": "A0A8V0YN80", "url": "https://omabrowser.org/oma/group/A0A8V0YN80/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P41183-1", "protein_name": "B-cell lymphoma 6 protein homolog", "gene_name": "Bcl6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASPADSCIQFTRHASDVLLNLNRLRSRDILTDVVIVVSREQFRAHKTVLMACSGLFYSIFTDQLKCNLSVINLDPEISPEGFCILLDFMYTSRLNLREGNIMAVMTTAMYLQMEHVVDTCRKFIKASEAEMAPALKPPREEFLNSRMLMPHDIMAYRGREVVENNMPLRNTPGCESRAFAPPLYSGLSTPPASYPMYSHLPLSTFLFSDEELRDAPRMPVANPFPKERALPCDSARQVPNEYSRPAMEVSPSLCHSNIYSPKEAVPEEARSDIHYSVPEGPKPAVPSARNAPYFPCDKASKEEERPSSEDEIALHFEPPNAPLNRKGLVSPQSPQKSDCQPNSPTESCSSKNACILQASGSPPAKSPTDPKACNWKKYKFIVLNSLNQNAKPEGSEQAELGRLSPRAYPAPPACQPPMEPANLDLQSPTKLSASGEDSTIPQASRLNNLVNRSLAGSPRSSSESHSPLYMHPPKCTSCGSQSPQHTEMCLHTAGPTFPEEMGETQSEYSDSSCENGTFFCNECDCRFSEEASLKRHTLQTHSDKPYKCDRCQASFRYKGNLASHKTVHTGEKPYRCNICGAQFNRPANLKTHTRIHSGEKPYKCETCGARFVQVAHLRAHVLIHTGEKPYPCEICGTRFRHLQTLKSHLRIHTGEKPYHCEKCNLHFRHKSQLRLHLRQKHGAITNTKVQYRVSAADLPPELPKAC", "length": 707 }, "evidence": [ { "id": "A0A8V0YN80", "url": "https://omabrowser.org/oma/group/A0A8V0YN80/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { 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predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052585.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. 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"https://www.uniprot.org/uniprotkb/A0A8V0YNA7", "locus": { "chromosome": "10", "start_pos": 12964867, "end_pos": 12988651, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010016181", "url": "https://www.ensembl.org/id/ENSGALG00010016181" } ] } } ], "crossref": [ { "id": "cd11720", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11720", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "415491", "url": "https://www.ncbi.nlm.nih.gov/gene/415491", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR026171", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026171", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029305", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029305", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029308", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029308", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029310", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029310", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029312", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029312", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029313", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029313", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029314", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029314", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029315", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029315", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:415491", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:415491", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QSMRMMN", "url": "https://omabrowser.org/oma/group/QSMRMMN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YNA7", "url": "https://www.orthodb.org/?gene=A0A8V0YNA7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YUQ9", "url": "https://www.orthodb.org/?gene=A0A8V0YUQ9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z1G8", "url": "https://www.orthodb.org/?gene=A0A8V0Z1G8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21818", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21818", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21818:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21818:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF14674", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14674", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14675", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14675", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14676", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14676", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14677", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14677", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14678", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14678", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14679", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14679", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14680", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14680", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-6783310", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6783310", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001108323", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001108323", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YNA7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNA7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YNA7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNA7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YUQ9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUQ9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YUQ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUQ9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z1G8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1G8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z1G8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1G8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAQRILQLAAEGSPERLQEALQGLTEGELGDMVTRQALRGRETAALLKGIFKGSPCSQQSGVLRRLQVYKHCVSLVESGDLHVGKVSEIIGLLMLEARQLPGHALAELATLFVEVIKRGSLSNGKSLELFSTVLTALSNSKESLAYGKGELNGEEFKKQLINTLCSSKWDPQCVIHLANMFRDIPLSGEELQFVVEKVLRMFSKLDLQEIPPLVYQLLLLSAKGSKKTVLEGIISFFNQLDKRQKEEQRVPQSADLEVATVPLDQLRHVEGTVILHIVSAINLDQDIGEELIKHLKTEQQKDPGKALCPFSVSLLLSTAVKHRLQEQIFDFLKTSITRSCKDLQILQASKFLQDLCPQQYDVTAVILEVVKNSAFGWDHVTQGLVDLGFSLMESYEPKKSFGGKAAETNLGLSKMPAQQACKLGASILLETFKVHEPIRSDILEQVLNRVLTKAASPVSHFIDLLSNIVVSAPLVLQNSSSRVTETFDNLSFLPIDTVQGLLRAVQPLLKVSMSVRDSLILVLQKAIFSRQLDARKAAVAGFLLLLRNFKILGSLTSSQCSQAIGATQVQADVHACYNSAANEAFCLEILGSLRRCLSQQADVRLMLYEGFYDVLRRNSQLASSIMETLLSQIKQYYLPQQDLLPPLKLEGCIMAQGDQIFLQEPLAHLLCCIQHCLAWYKSTVHLCKGAEDEEEEEDVGFEQNFEEMLESVTRRMIKSELEDFELDKSADFSPSSGVGVKNNIYAIQVMGICEVLIEYNFKIGNFSKNKFEDVLGLFTCYNKLSEILKEKAGKNKSTLGNRIARSFLSMGFVSTLLTALFRDNAQSHEESLAVLRSSTEFMRYAVSVALQKVQQLEEMGQTDGPDGQNPEKMFQNLCKITRVLLWRYTSIPTAVEEPGKKKGKSISLLCLEGLLRIFNTMQQLYAARIPQFLQALDITDGDAEEADINVTEKAAFQIRQFQRSLVNQLSSAEDDFNSKETQLLITILSTLSKLLDPGSQQFLQFLTWTVKICKENALEDLSCCKGLLTLLFSLHVLYKSPVSLLRELAQDIHACLGDIDQDVEIESRSHFAIVNVKTAAPTVCLLVLGQADKVLEEVDWLIKRLTILGSDTSEDSTQASNQTQALEKGVILQLGTLLTVFHELVQTALPAGSCVDSLLRSLSKTYAILTSLIKHYIQACRSTSNTVPGRLEKLVKLSGSHLTPQCYSFITYVQNIHSESLSFAEEKKKKKKEDETAVVSTVMAKVLRDTKPIPNLIFAIEQYEKFLIHLSKKSKVNLMQYMKLSTSRDFRINASMLDSVLQEQNTEDAENEPDNNQSGTAEQPDENQEPQKKRRRKK", "length": 1338, "header": "tr|A0A8V0YNA7-1|A0A8V0YNA7_CHICK Isoform 1 of Fanconi anemia complementation group I OS=Gallus gallus OX=9031 GN=FANCI PE=4 SV=1 CANONICAL=A0A8V0YNA7-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YNA7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNA7/entry#A0A8V0YNA7-1", "sequence": { "sequence": "MAQRILQLAAEGSPERLQEALQGLTEGELGDMVTRQALRGRETAALLKGIFKGSPCSQQSGVLRRLQVYKHCVSLVESGDLHVGKVSEIIGLLMLEARQLPGHALAELATLFVEVIKRGSLSNGKSLELFSTVLTALSNSKESLAYGKGELNGEEFKKQLINTLCSSKWDPQCVIHLANMFRDIPLSGEELQFVVEKVLRMFSKLDLQEIPPLVYQLLLLSAKGSKKTVLEGIISFFNQLDKRQKEEQRVPQSADLEVATVPLDQLRHVEGTVILHIVSAINLDQDIGEELIKHLKTEQQKDPGKALCPFSVSLLLSTAVKHRLQEQIFDFLKTSITRSCKDLQILQASKFLQDLCPQQYDVTAVILEVVKNSAFGWDHVTQGLVDLGFSLMESYEPKKSFGGKAAETNLGLSKMPAQQACKLGASILLETFKVHEPIRSDILEQVLNRVLTKAASPVSHFIDLLSNIVVSAPLVLQNSSSRVTETFDNLSFLPIDTVQGLLRAVQPLLKVSMSVRDSLILVLQKAIFSRQLDARKAAVAGFLLLLRNFKILGSLTSSQCSQAIGATQVQADVHACYNSAANEAFCLEILGSLRRCLSQQADVRLMLYEGFYDVLRRNSQLASSIMETLLSQIKQYYLPQQDLLPPLKLEGCIMAQGDQIFLQEPLAHLLCCIQHCLAWYKSTVHLCKGAEDEEEEEDVGFEQNFEEMLESVTRRMIKSELEDFELDKSADFSPSSGVGVKNNIYAIQVMGICEVLIEYNFKIGNFSKNKFEDVLGLFTCYNKLSEILKEKAGKNKSTLGNRIARSFLSMGFVSTLLTALFRDNAQSHEESLAVLRSSTEFMRYAVSVALQKVQQLEEMGQTDGPDGQNPEKMFQNLCKITRVLLWRYTSIPTAVEEPGKKKGKSISLLCLEGLLRIFNTMQQLYAARIPQFLQALDITDGDAEEADINVTEKAAFQIRQFQRSLVNQLSSAEDDFNSKETQLLITILSTLSKLLDPGSQQFLQFLTWTVKICKENALEDLSCCKGLLTLLFSLHVLYKSPVSLLRELAQDIHACLGDIDQDVEIESRSHFAIVNVKTAAPTVCLLVLGQADKVLEEVDWLIKRLTILGSDTSEDSTQASNQTQALEKGVILQLGTLLTVFHELVQTALPAGSCVDSLLRSLSKTYAILTSLIKHYIQACRSTSNTVPGRLEKLVKLSGSHLTPQCYSFITYVQNIHSESLSFAEEKKKKKKEDETAVVSTVMAKVLRDTKPIPNLIFAIEQYEKFLIHLSKKSKVNLMQYMKLSTSRDFRINASMLDSVLQEQNTEDAENEPDNNQSGTAEQPDENQEPQKKRRRKK", "length": 1338, "header": "tr|A0A8V0YNA7-1|A0A8V0YNA7_CHICK Isoform 1 of Fanconi anemia complementation group I OS=Gallus gallus OX=9031 GN=FANCI PE=4 SV=1 CANONICAL=A0A8V0YNA7-1" }, "locus": { "chromosome": "10", "start_pos": 12988593, "end_pos": 12965740, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010038894.1", "url": "https://www.ensembl.org/id/ENSGALT00010038894.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010022478.1", "url": "https://www.ensembl.org/id/ENSGALP00010022478.1" } ] } }, { "isoform_ac": "A0A8V0YUQ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNA7/entry#A0A8V0YUQ9-1", "sequence": { "sequence": "MAQRILQLAAEGSPERLQEALQGLTEGELGDMVTRQALRGRETAALLKGIFKGSPCSQQSGVLRRLQVYKHCVSLVESGDLHVGKVSEIIGLLMLEARQLPGHALAELATLFVEVIKRGSLSNGKSLELFSTVLTALSNSKESLAYGKGELNGEEFKKQLINTLCSSKYVQCLFLDIPLSGEELQFVVEKVLRMFSKLDLQEIPPLVYQLLLLSAKGSKKTVLEGIISFFNQLDKRQKEEQRVPQSADLEVATVPLDQLRHVEGTVILHIVSAINLDQDIGEELIKHLKTEQQKDPGKALCPFSVSLLLSTAVKHRLQEQIFDFLKTSITRSCKDLQILQASKFLQDLCPQQYDVTAVILEVVKNSAFGWDHVTQGLVDLGFSLMESYEPKKSFGGKAAETNLGLSKMPAQQACKLGASILLETFKVHEPIRSDILEQVLNRVLTKAASPVSHFIDLLSNIVVSAPLVLQNSSSRVTETFDNLSFLPIDTVQGLLRAVQPLLKVSMSVRDSLILVLQKAIFSRQLDARKAAVAGFLLLLRNFKILGSLTSSQCSQAIGATQVQADVHACYNSAANEAFCLEILGSLRRCLSQQADVRLMLYEGFYDVLRRNSQLASSIMETLLSQIKQYYLPQQDLLPPLKLEGCIMAQGDQIFLQEPLAHLLCCIQHCLAWYKSTVHLCKGAEDEEEEEDVGFEQNFEEMLESVTRRMIKSELEDFELDKSADFSPSSGVGVKNNIYAIQVMGICEVLIEYNFKIGNFSKNKFEDVLGLFTCYNKLSEILKEKAGKNKSTLGNRIARSFLSMGFVSTLLTALFRDNAQSHEESLAVLRSSTEFMRYAVSVALQKVQQLEEMGQTDGPDGQNPEKMFQNLCKITRVLLWRYTSIPTAVEEPGKKKGKSISLLCLEGLLRIFNTMQQLYAARIPQFLQALDITDGDAEEADINVTEKAAFQIRQFQRSLVNQLSSAEDDFNSKETQLLITILSTLSKLLDPGSQQFLQFLTWTVKICKENALEDLSCCKGLLTLLFSLHVLYKSPVSLLRELAQDIHACLGDIDQDVEIESRSHFAIVNVKTAAPTVCLLVLGQADKVLEEVDWLIKRLTILGSDTSEDSTQASNQTQALEKGVILQLGTLLTVFHELVQTALPAGSCVDSLLRSLSKTYAILTSLIKHYIQACRSTSNTVPGRLEKLVKLSGSHLTPQCYSFITYVQNIHSESLSFAEEKKKKKKEDETAVVSTVMAKVLRDTKPIPNLIFAIEQYEKFLIHLSKKSKVNLMQYMKLSTSRDFRINASMLDSVLQEQNTEDAENEPDNNQSGTAEQPDENQEPQKKRRRKK", "length": 1331, "header": "tr|A0A8V0YUQ9-1|A0A8V0YUQ9_CHICK Computationally mapped isoform of Fanconi anemia complementation group I OS=Gallus gallus OX=9031 GN=FANCI PE=4 SV=1 CANONICAL=A0A8V0YNA7-1" }, "locus": { "chromosome": "10", "start_pos": 12988593, "end_pos": 12965740, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010038899.1", "url": "https://www.ensembl.org/id/ENSGALT00010038899.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010022480.1", "url": "https://www.ensembl.org/id/ENSGALP00010022480.1" } ] } }, { "isoform_ac": "A0A8V0Z1G8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNA7/entry#A0A8V0Z1G8-1", "sequence": { "sequence": "MAQRILQLAAEGSPERLQEALQGLTEGELGDMVTRQALRGRETAALLKGIFKGSPCSQQSGVLRRLQVYKHCVSLVESGDLHVGKVSEIIGLLMLEARQLPGHALAELATLFVEVIKRGSLSNGKSLELFSTVLTALSNSKESLAYGKGELNGEEFKKQLINTLCSSKWDPQCVIHLANMFRDIPLSGEELQFVVEKVLRMFSKLDLQEIPPLVYQLLLLSAKGSKKTVLEGIISFFNQLDKRQKEEQRVPQSADLEVATVPLDQLRHVEGTVILHIVSAINLDQDIGEELIKHLKTEQQKDPGKALCPFSVSLLLSTAVKHRLQEQIFDFLKTSITRSCKDLQILQASKFLQDLCPQQYDVTAVILEVVKNSAFGWDHVTQGLVDLGFSLMESYEPKKSFGGKAAETNLGLSKMPAQQACKLGASILLETFKVHEPIRSDILEQVLNRVLTKAASPVSHFIDLLSNIVVSAPLVLQNSSSRVTETFDNLSFLPIDTVQGLLRAVQPLLKVSMSVRDSLILVLQKAIFSRQLDARKAAVAGFLLLLRNFKILGSLTSSQCSQAIGATQVQADVHACYNSAANEAFCLEILGSLRRCLSQQADVRLMLYEGFYDVLRRNSQLASSIMETLLSQAHLLCCIQHCLAWYKSTVHLCKGAEDEEEEEDVGFEQNFEEMLESVTRRMIKSELEDFELDKSADFSPSSGVGVKNNIYAIQVMGICEVLIEYNFKIGNFSKNKFEDVLGLFTCYNKLSEILKEKAGKNKSTLGNRIARSFLSMGFVSTLLTALFRDNAQSHEESLAVLRSSTEFMRYAVSVALQKVQQLEEMGQTDGPDGQNPEKMFQNLCKITRVLLWRYTSIPTAVEEPGKKKGKSISLLCLEGLLRIFNTMQQLYAARIPQFLQALDITDGDAEEADINVTEKAAFQIRQFQRSLVNQLSSAEDDFNSKETQLLITILSTLSKLLDPGSQQFLQFLTWTVKICKENALEDLSCCKGLLTLLFSLHVLYKSPVSLLRELAQDIHACLGDIDQDVEIESRSHFAIVNVKTAAPTVCLLVLGQADKVLEEVDWLIKRLTILGSDTSEDSTQASNQTQALEKGVILQLGTLLTVFHELVQTALPAGSCVDSLLRSLSKTYAILTSLIKHYIQACRSTSNTVPGRLEKLVKLSGSHLTPQCYSFITYVQNIHSESLSFAEEKKKKKKEDETAVVSTVMAKVLRDTKPIPNLIFAIEQYEKFLIHLSKKSKVNLMQYMKLSTSRDFRINASMLDSVLQEQNTEDAENEPDNNQSGTAEQPDENQEPQKKRRRKK", "length": 1304, "header": "tr|A0A8V0Z1G8-1|A0A8V0Z1G8_CHICK Computationally mapped isoform of Fanconi anemia complementation group I OS=Gallus gallus OX=9031 GN=FANCI PE=4 SV=1 CANONICAL=A0A8V0YNA7-1" }, "locus": { "chromosome": "10", "start_pos": 12988593, "end_pos": 12965740, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010038885.1", "url": "https://www.ensembl.org/id/ENSGALT00010038885.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010022474.1", "url": "https://www.ensembl.org/id/ENSGALP00010022474.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:415491", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:415491", "resource": "KEGG Pathway" }, { "id": "R-GGA-6783310", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6783310", "resource": "Reactome", "description": "Fanconi Anemia Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A1P8BDX4-1", "protein_name": "Fanconi anemia group I-like protein", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MTVAAAAEEPSQRPLTDKDIIRLAQYHHCQTGFSLPPYLLSPSSHDSLLSYLKSRSSSPSPSKQVSEYVIALLSLISLSPTTPSLCSLLASLLISYTQIFNSCKIPSDSDSLKTIQLFGTLLRYLHVKEVKSVVDSILSGVTRVITVDEAQVFDLLPVCFDLLRREGKASEIDFVNSAIDRVLSCEWNKALLTKMVSLAKEFSFLDKGRKSELVEKVFVGIKLIDLQDLPSLVYQLLVLASKGFCKREVIGGVVGYFGSKAETRVASVVRQIEGTVLLHVNFAVKQDPSLGQEVVALVKSDLRAFNHFTVAVLFSVARVRKFGESSLGMLRTALLTAYNDYRLSKDCKWLPVELKEESFLHAKLVEKSLLRAVSECRYGREHVVPSVIQFGFMLLESVEEGRSNEFGDSKGVLGIEKLSIQILGTLFEVHDMTRNEIIEQCKFRILSLKCAKSKPIVRLLGYLVQRYSLIMLEFVHHLKELLDYFTFMEGHISCFLVSAVIPLIKFSRDLQDYTILVIRKAMFRREDTVRVAATKVITDLILAEKLAKRDSSFTFQDSASQASSSQQTEMSCIVRGNLFTELNGLLQRCLYQQARVKEVVYDGLVKLVLIDPSSGGHVLDFLMPHFLRFFGQDTDFQLGITSCIRVEGDKFTIEEPLDRLLFCVSWILLLQQQNSSDRPSDAAWPCFGFSLSQDNEQQVGRNLSHEAYSSALVKIRSFLLGKKLGDIVGQSQDTVSASLEEDKRKSYCLIILGIVQVLLNYIIVDLEKQPEGKKGSVRKEIVDLIDLYESLEKDVGKSKQSNVGKRVRFSACNDTDLGNTSINEEREKVPFLATSSIYQLFLLSFKLYSSKSVGTQSGSQDHSHSSPAKTEKSIFSFTLHVCVGHINSSLCMKEENPLKPLVCGDMKVLGPPLLKVVYLLKPEPPLATGQTNKEKKGRKDVDGRKQCLHLALLSLKELLNIYSSGSGLTGLLEDLLAVPASEDATLEECREASKIEDPLIKSIEIFMAKIMKPMITDFIAQNSNDVEILCDIMLKLGNNLPDKFKQRHGSWAHQICRSCETSNTTVAKSVLKLAISFTTSPGDLCIAVEVAQELQNIMGLDKSDTLEVSESYMVINQSTSASVTSCILQSIDSAIVDMDWATKKLKNFYVVSQKNIHLSDDTESTVGSVLEEALYSMAESTVRILSSFVLMNLKESQAAQFLRLAVRFYKQLAQIVKLRIAPKGCKQILPSLKFQKLVELTCKSLTVPLYPFLSEMQKEQQESVSHNSKGIINKIKQENKCIPDLIFQIEDCERYLIQLSKVTKLNLLRHAKRSTARDFKIIEDSDPPAGGEDGGNQEEETETQNNNIGEDDLRQESDDDGSEEMLSPRNASSVSSPGLDSDKTIAAATEEDDEEEQEQDEGEEESGDNRPKKMARKSWVVEDSDEDSETF", "length": 1431 }, "evidence": [ { "id": "A0A8V0YNA7", "url": "https://omabrowser.org/oma/group/A0A8V0YNA7/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "A0A8C2MN62-1", "protein_name": "Fanconi anemia group I protein isoform X1", "gene_name": "Fanci", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MDLKILSLATDKTTDKLQEFLQTLKTDDLTDLLQSRAVKGRAVGTFLRAIFKGSPCSEEDGALRRSKVYSCCIQLVESGDLQQEVASEIIGLLMLEVHHFPGPLLVELASEFVGAIREDSLVNGKSLELFPIILTALATKKEVLTCGKGDLNGEEYKRQLIDSLCSVRWAQRYVIQLTSMFKDVRLTTEEMDLVVAKVLSMFSKLNLQEIPPLVYQLLVLSSKGSRRSVLDGIIAFFNELDKQHSEEQSSDELLELVTTPADELYHVEGTVILHIVFAVKLDCELGRELLKHVKAGQQGDPSKSLCPFSIALLLSLTRIQRFEEQVFDLLKTSVIKSFKDLQLLQGSKFLQNLVPQKTCVSSMILEVAKNSVHSWDHVTQGLIELGFILMDSYGPKKILDGRAVEIGSSLSKMTNQHACKLGANILLETFKIHEMIRQEILEQVLNRVVTRTSSPINHFLDLLSDIILYAPLILQSCSKVTETFDYLSFLPLQTVQGLLKAVQPLLKVSMSMRDALILVLRKAMFASQLDSRKSAVAGFLLLLKNFKVLGSLSSSQCSQSIGATQVHVDVHSRYNAVANETFCLEIMDSLKRCLGQQADIRLMLYEGFYDVLRRNSRLANSIMQTLFSQLKQFYEPEPDLLPPLKLGACVLTQGSQVILQEPLDHLLSCIQHCLAWYKSRVIPLQQGDEREEEEGLYHELDDMLESITMRMIKSELEDFELDKSADFSQSTSVGIKNNVCACLIMGVCEVLIEYNFSISNFSKSKFEEILSLFMCYKNFSDILAEKAGKGKTKMTAKTNDSLLSMKFVSDLLTALFRDSIQSHEEALSVLRSSSEFMQYAVNVALQKTQQLIRTGHVSGPDGQNPDKVFQNLCDITRVLLWRYTSIPTSVEESGKKEKGKSISLLCLEGLQKTFNAMQQFYQPKMQQFLRALDVTGTEEEGEEAGVSVTQRATFQIRQFQRSLLNLLSSEEEDFNSKEALLLITILSSLSRLIEPTSPQFVQVLSWTSKICKEYSREDTSFCKSLMNLFFSLHVLYKSPVTLLRDLSQDIHGQLGDIDQDVEIEKTDHYAMVNLRTAAPTVCLLVLSQAEKVLEEVDWLITKIKSSVNQETLSDKMAPDASSQAVPPNLLIEKAIVMQLGTLVTFFHELVQTALPSGSCVDTLLKDLSKIYSTLTAFVKYYLQVCQSARGIPNTVEKLVKLSGSHLTPMCYSFISYVQNKGNDNPKCTEKEKAAGASTIMAKVLRETKPIPNLVFAIEQYEKFLIQLSKKSKVNLMQHMKLSTSRDFKIKGSILDMVLREDEDENEEGAAPAHREQDREPATKKRKICLS", "length": 1330 }, "evidence": [ { "id": "A0A8V0YNA7", "url": "https://omabrowser.org/oma/group/A0A8V0YNA7/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8M9PUU2-1", "protein_name": "Fanconi anemia group I protein isoform X1", "gene_name": "fanci", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSKMKVTVDSILSLSETDDGDELQKHLTLLSDDQLTTMLTNSALKGKDTGILIKAIFKGSPVSVSHGANRRLLVYKHCIPLCESGDLQTEVASDIIGLLMLDTHSLPGPALATLASLYVDAIKVGEMNSGRSLELFPTILTALSATDALAYGKGELTGNEYKKQLINSLCSSRWDPQCVIHLTTMFRDVPLSTEELQFLIEKILRMFLKLDLQEIPPLVYQLLLLSAKGCKKLVLEGIINYFKKQDQLQKEEQRNGECEDVEVQTIPQDQLRHVEGTVILHIVFAIRLDHELGREFFKNLKVAQSDPLCPFSIALLLSVARIQRYEEQVFEFLKGAITKNFKDDQIQNSSKFLQDLLPQFSSVSDMILDTVKNSVFGWDHVTQGLVQLGFILMDSFGPKPGPFGKVTEGTSSTAKTPNQLACRLGGQVLLESFKMHEPIRGEILEQVLNRLVTKTASPVTHFIDLLSSIVLSAPMILLESSSKVTETFDQLSYLPLSTVQGLLKAVQPLLKVSMSMKDALILVLRKAMFSSHLDGRKSAVAGFLLLLKNFRILGSLASSQASQAITSSQVQADVHSRYNTAANEAFCLEILSSLRRCLNQQADVRLMLYEGFHDVLRRNSQLASSITQTLLSQLKRYFEPEQDLLPPVKLESCISAQGDQVFLQEPLAHLLCCTVHCLLWNQNVRSGGNVSDDEDDEEDVGGVESELQAMLESITKRMIKSELEDFELDKCAEFSTGSSVGVKNSIYAVLVMGLNEVLMEYNFITANYSKNHFEDVLELFKRYLKVCDILRERAGKGRPASSKTPRSLLSLGFVSTLLTALFRDSTQSREESLSVLRSNGDFLRYSVSVALQKIQQLEETGHTDGPEGQSPDKTFRHLCDITSVLMWRYTNVPSTVEDAGKKEKGQSVSLLCLEGLLRVFTTVLQRYPTRVSNFLSSLDVSGEGEGDKSDLTEQTAFYIRQFQRALMNQLSGPEEEFNSKEAQLLVSILSVLSRQLSPSSQQFLQMITWTVKICKETNFEDIALTKGLLSLLFSLYVLHKSPVSLLWEMCQDIHSQLGDIDQDVEVEKQSHFAIICMKTAASTTLQVLSQVGKVLDEVDWLIAKKKAQISSDRTISGNTQQPLGQQDPIEKAITIQLGTLLTALHELVQTALPTGACTDTLMRELSRTYCILTTLTKYYIQLCATQPGQLPARLEKLVKLSGSHLTPQCYCFITYVQSGELTAGGSEKLKKKKKEEEAVAAASAKVLRETKAIPNLIFNIEQYEKFLILLSKKSKVNLMQYMKLSTSRDFRINAATLEAALQEQEQDQSQQVSLSKQPHLQTHLQEFSRFQCFFPSVFRVKMLRVKHQRKKGGRSERRSLQSLFCTFPPSYLFISG", "length": 1376 }, "evidence": [ { "id": "A0A8V0YNA7", "url": "https://omabrowser.org/oma/group/A0A8V0YNA7/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A1Z7L1-1", "protein_name": "Fanconi anemia group I protein homolog", "gene_name": "Fanci", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MRSLGEKARFDELELLIQNTPIEKLKETLKSTMTRSEGITYWNYLLRGFNPESKDALAKRFECVRSFMDGLSSTELSYKQTFDLITRLSQDLATFPSEQLAWIVEHCMDGIRQGDAKCVGWKDLLPDALSLLLARPRFLLNGISIDGMEFRDTTVRSIATMQWPASILTPIADMFKTMNLSSGEIVTVLNKFSGALQELSPMELPALCFQLFSMCSTASQLIIPLLALEKYFHRNYYKRLFSDMCSNSTNLDSIDLFSDKELREAEETILHHLNYCTMYKLTEKHLAIMLRNFLHMPDVILTPFMLSAIISMTSINRDPESARISHSILLPFLRNVIKNNEEERTLADYSVWYRDTLQRKQVDLQQVLTVLIDQNKDGKDVITPGLVHLVFYLLKSQSPKMHTLAITFLTKFIRKRFIFGQGIIKLISEWMIVYQEQNQFSECLTLLSVADTYTVSECMKPIQSVLEHMQWLSGEQSMRMMNFILPLLKISNRVRDALIDVLCKAMSSSGIQKRRMAIYGFCMILKQLNNSNAVRQTSSATSFCTQHSISGYSIMTQNTLGSRSNPQRNFDMLTLEIIGMLRNCLQQQFDIRCSLYENLQRAVELNAKLVPHVLQVIDWHFRSFFDTPSAEDAGDDLDTVFRIRYDQLVSSSDDQHMEIQLKDNLGKLIQFVANCLAVFDRAPSGYDTREMNRLMSFCVDRMVANRLPLEEITPPATHLKCALVLQQLNIIEGIICHLLLKSKPQNNAVCQILPLFNQHCKLLESLKALSDASKKAHKQLKQTAKNNSTSTCNLTLNGVPVKTMCTQPDNIWDLAILDKLLHLLLDDVVAFAAPEKTVLLRSNEPLVRYVLSVTASRVESIRLEPDYKQLAYSKRTFKQLTDITKVIYERCIQRLPELWKNFDMQSAALATQCFSECLKTAHETYSKKFEDFVKSFDLASIKGSRNKEVVYTIQDVLDDFMTEYGTDDSICKNEFVSKLPVYLLESLEILLDHIDYQDRAATESYTWLLNFCSKNEILNSEMGLVHRMLFVQRQKTHLGPFFDSVARQLGHVLGVQNEDAPSESVELTLKSISTVTIESCLQHLYAAIQKQLNDVDYFVTKANNLNYKCQVVPEIDQIYWRGNLDSMDRSICTQIIHISRTLLVLTNVCIPLGSLMDGLMKLLIQHYTCLKSLTKHYISSYTSDTSIENIKSTKFELLLRAVGKQLPANIYELITYIEANTLDEEAQQHTKKRKVQAERAKVLRETRLIPKVIMVIEDFNKHIILLSKKTKSKNRLTDYLHLGTMRDFDIKSTDLRAAIERSISDGRNISTEDSNAEDRDEDEDENENVEEDDDAQSTTYPEDLEEKEDECLVIEKKEERRRRRAPSSEAEDPQPKRKRGRKAAEQLEAEDEEQVEEEQPETTLKLRRNKKVEPKTKRSVAIKKPEEQPSHESRTSKRSKGPADKQTAEPAKVDLCVPEVPAEKKKPQPSRRLGIPRTLRK", "length": 1481 }, "evidence": [ { "id": "A0A8V0YNA7", "url": "https://omabrowser.org/oma/group/A0A8V0YNA7/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "D3Z840-1", "protein_name": "FA complementation group I", "gene_name": "Fanci", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDLKILSLATDKTTDKLQEFLQTLKADDLASLLESQAVKGRAVGTFLRAILKGSPCSEEDGALRRYKIYSCCIQLVESGDLQQDVASEIIGLLMLEVHHFPGPLLVDLANDFVGAVREDRLVNGKSLELLPIILTALATKKEGLTCGKGDLNGEECKRQLIDTLCSVRWAQRYVIQLTSVFKDVRLTPEEMKLVVAKVLTMFSRLNLQEIPPLVYQLLVLSSKGSRRSVLDGIIAFFRELDKQHSAEQSSDELSELVTAPADELHHVEGTIILHIVFAIKLDCELGRELLKHLKAGQQGDPSKCLCPFSIALLLSLTRIQRFEEQVFDFLKTSVVKSFKDLQLLQGSKFLQTLVPQRTCVSTMILEVVKNSVHSWDHVTQGLIEFGFILMDSYGPKKILDGKAVEIGSSLSKMTNQHACKLGADILLETFKIHEMIRQEILEQVLNRVVTRTSSPISHFLDLFSDIIMYAPLILQSCSKVTETFDYLSFLPLQTVQGLLKAVQPLLKISMSMRDSLILVLRKALFASQLDARKSAVAGFLLLLKNFKVLGSLPSSQCTQSIGVTQVHVDVHSRYSAVANETFCLEIIDSLKRCLGQQADVRLMLYEGFYDVLRRNSQLASSIMQTLFSQLKQFYEPEPDLLPPLKLGACVLTQGSQTFLQEPLGHLLSCIQHCLAWYKSRVVPLQQGDEGEEEQEEEELYHELDDMLESITIRMIKSELEDFELDKSADFSQNNNVGIKNNICASLVMGVCEVLMEYNFSISNFSKSKSEEILSLFMCYKKFSDILSEKAGKGKAKMASKASDSLLSMKFVSDLLTALFRDSIQSHEESLSVLRSSSEFMHYALNVALQKVQQLTRTGCVSGPDGQNPDRIFQHLCDITRVLFWRYTSIPTSVEESAKKEKGKSISLLCLEALQKTFSAVLQFYQPKVQQFLQALDVMSTEEEEAGVTVTQRASFQIRQFQRSLLNLLSSQEEDFNSKEALLLVTVLSTLSKLLEPTSPQFVQMLSWTSKICKEHSQEDASFCKSLMSLFFSLHVLYKSPVTLLRDLSQDIHGQLGDIDQDVEIEKTDHFAIVNLRTAAPTVCLLVLSQAEKVLEEVDWLITKIKGSVNQETLSDEMTPEDASSQAVPPTVHIEKAITMQLGTLVTFFHELVQTALPSGSCVDTLLKDLSKIYSTLTAFVKYYLQVCQSSRRIPNTVEKLVKLSGSHLTPVCYSFISYVQNKSSNNPKCPEKEKAAVSKSMAKVLRETKPIPNLVFAIEQYEKFLIQLSKKSKVNLMQHMKLSTSRDFKIKGNVLDMVLREEGEDENEEGTASAHTQQDREPAKKRRKKCLS", "length": 1332 }, "evidence": [ { "id": "A0A8V0YNA7", "url": "https://omabrowser.org/oma/group/A0A8V0YNA7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8K368-1", "protein_name": "Fanconi anemia group I protein homolog", "gene_name": "Fanci", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDLKILSLATDKTTDKLQEFLQTLKDDDLASLLQNQAVKGRAVGTLLRAVLKGSPCSEEDGALRRYKIYSCCIQLVESGDLQQDVASEIIGLLMLEVHHFPGPLLVDLASDFVGAVREDRLVNGKSLELLPIILTALATKKEVLACGKGDLNGEEYKRQLIDTLCSVRWPQRYMIQLTSVFKDVCLTPEEMNLVVAKVLTMFSKLNLQEIPPLVYQLLVLSSKGSRRSVLDGIIAFFRELDKQHREEQSSDELSELITAPADELYHVEGTVILHIVFAIKLDCELGRELLKHLKAGQQGDPSKCLCPFSIALLLSLTRIQRFEEQVFDLLKTSVVKSFKDLQLLQGSKFLQTLVPQRTCVSTMILEVVRNSVHSWDHVTQGLIEFGFILMDSYGPKKILDGKAVEIGTSLSKMTNQHACKLGANILLETFKIHEMIRQEILEQVLNRVVTRTSSPINHFLDLFSDIIMYAPLILQNCSKVTETFDYLTFLPLQTVQGLLKAVQPLLKISMSMRDSLILVLRKAMFASQLDARKSAVAGFLLLLKNFKVLGSLPSSQCTQSIGVTQVRVDVHSRYSAVANETFCLEIIDSLKRSLGQQADIRLMLYDGFYDVLRRNSQLASSIMQTLFSQLKQFYEPEPDLLPPLKLGACVLTQGSQIFLQEPLDHLLSCIQHCLAWYKSRVVPLQQGDEGEEEEEELYSELDDMLESITVRMIKSELEDFELDKSADFSQNTNVGIKNNICACLIMGVCEVLMEYNFSISNFSKSKFEEILSLFTCYKKFSDILSEKAGKGKAKMTSKVSDSLLSLKFVSDLLTALFRDSIQSHEESLSVLRSSGEFMHYAVNVTLQKIQQLIRTGHVSGPDGQNPDKIFQNLCDITRVLLWRYTSIPTSVEESGKKEKGKSISLLCLEGLQKTFSVVLQFYQPKVQQFLQALDVMGTEEEEAGVTVTQRASFQIRQFQRSLLNLLSSEEDDFNSKEALLLIAVLSTLSRLLEPTSPQFVQMLSWTSKICKEYSQEDASFCKSLMNLFFSLHVLYKSPVTLLRDLSQDIHGQLGDIDQDVEIEKTDHFAVVNLRTAAPTVCLLVLSQAEKVLEEVDWLIAKIKGSANQETLSDKVTPEDASSQAVPPTLLIEKAIVMQLGTLVTFFHELVQTALPSGSCVDTLLKGLSKIYSTLTAFVKYYLQVCQSSRGIPNTVEKLVKLSGSHLTPVCYSFISYVQNKSSDAPKCSEKEKAAVSTTMAKVLRETKPIPNLVFAIEQYEKFLIQLSKKSKVNLMQHMKLSTSRDFKIKGSVLDMVLREDEEDENEEGTASAHTQQDREPAKKRRKKCLS", "length": 1330 }, "evidence": [ { "id": "A0A8V0YNA7", "url": "https://omabrowser.org/oma/group/A0A8V0YNA7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9NVI1-3", "protein_name": "Fanconi anemia group I protein", "gene_name": "FANCI", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDQKILSLAAEKTADKLQEFLQTLREGDLTNLLQNQAVKGKVAGALLRAIFKGSPCSEEAGTLRRRKIYTCCIQLVESGDLQKEIASEIIGLLMLEAHHFPGPLLVELANEFISAVREGSLVNGKSLELLPIILTALATKKENLAYGKGVLSGEECKKQLINTLCSGRWDQQYVIQLTSMFKDVPLTAEEVEFVVEKALSMFSKMNLQEIPPLVYQLLVLSSKGSRKSVLEGIIAFFSALDKQHNEEQSGDELLDVVTVPSGELRHVEGTIILHIVFAIKLDYELGRELVKHLKVGQQGDSNNNLSPFSIALLLSVTRIQRFQDQVLDLLKTSVVKSFKDLQLLQGSKFLQNLVPHRSYVSTMILEVVKNSVHSWDHVTQGLVELGFILMDSYGPKKVLDGKTIETSPSLSRMPNQHACKLGANILLETFKIHEMIRQEILEQVLNRVVTRASSPISHFLDLLSNIVMYAPLVLQSCSSKVTEAFDYLSFLPLQTVQRLLKAVQPLLKVSMSMRDCLILVLRKAMFANQLDARKSAVAGFLLLLKNFKVLGSLSSSQCSQSLSVSQVHVDVHSHYNSVANETFCLEIMDSLRRCLSQQADVRLMLYEGFYDVLRRNSQLANSVMQTLLSQLKQFYEPKPDLLPPLKLEACILTQGDKISLQEPLDYLLCCIQHCLAWYKNTVIPLQQGEEEEEEEEAFYEDLDDILESITNRMIKSELEDFELDKSADFSQSTSIGIKNNICAFLVMGVCEVLIEYNFSISSFSKNRFEDILSLFMCYKKLSDILNEKAGKAKTKMANKTSDSLLSMKFVSSLLTALFRDSIQSHQESLSVLRSSNEFMRYAVNVALQKVQQLKETGHVSGPDGQNPEKIFQNLCDITRVLLWRYTSIPTSVEESGKKEKGKSISLLCLEGLQKIFSAVQQFYQPKIQQFLRALDVTDKEGEEREDADVSVTQRTAFQIRQFQRSLLNLLSSQEEDFNSKEALLLVTVLTSLSKLLEPSSPQFVQMLSWTSKICKENSREDALFCKSLMNLLFSLHVSYKSPVILLRDLSQDIHGHLGDIDQDVEVEKTNHFAIVNLRTAAPTVCLLVLSQAEKVLEEVDWLITKLKGQVSQETLSEEASSQATLPNQPVEKAIIMQLGTLLTFFHELVQTALPSGSCVDTLLKDLCKMYTTLTALVRYYLQVCQSSGGIPKNMEKLVKLSGSHLTPLCYSFISYVQNKSKSLNYTGEKKEKPAAVATAMARVLRETKPIPNLIFAIEQYEKFLIHLSKKSKVNLMQHMKLSTSRDFKIKGNILDMVLREDGEDENEEGTASEHGGQNKEPAKKKRKK", "length": 1328 }, "evidence": [ { "id": "A0A8V0YNA7", "url": "https://omabrowser.org/oma/group/A0A8V0YNA7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNA7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNA7" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNA7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNA7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "DNA repair", "id": "GO:0006281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006281", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNA7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNA7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "DNA polymerase binding", "id": "GO:0070182", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070182", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNA7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNA7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1121, "end_pos": 1123, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1293, "end_pos": 1295, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1316, "end_pos": 1318, "annotation": "n_glycosylation_sequon" }, { "start_pos": 478, "end_pos": 480, "annotation": "n_glycosylation_sequon" }, { "start_pos": 489, "end_pos": 491, "annotation": "n_glycosylation_sequon" }, { "start_pos": 765, "end_pos": 767, "annotation": "n_glycosylation_sequon" }, { "start_pos": 795, "end_pos": 797, "annotation": "n_glycosylation_sequon" }, { "start_pos": 949, "end_pos": 951, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YNA7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNA7" }, { "id": "PF14679", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14679" }, { "id": "PF14680", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14680" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "FANCI helical", "eco_id": "ECO_0000259", "start_pos": 287, "end_pos": 372, "start_aa": "Ile", "end_aa": "Asn", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0YNA7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNA7" }, { "id": "PF14675", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14675" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "FANCI solenoid 1", "eco_id": "ECO_0000259", "start_pos": 64, "end_pos": 281, "start_aa": "Arg", "end_aa": "Ile", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0YNA7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNA7" }, { "id": "PF14674", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14674" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "FANCI solenoid 1 cap", "eco_id": "ECO_0000259", "start_pos": 1, "end_pos": 53, "start_aa": "Met", "end_aa": "Gly", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0YNA7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNA7" }, { "id": "PF14676", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14676" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "FANCI solenoid 2", "eco_id": "ECO_0000259", "start_pos": 380, "end_pos": 543, "start_aa": "Val", "end_aa": "Leu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0YNA7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNA7" }, { "id": "PF14677", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14677" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "FANCI solenoid 3", "eco_id": "ECO_0000259", "start_pos": 807, "end_pos": 1031, "start_aa": "Phe", "end_aa": "Leu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0YNA7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNA7" }, { "id": "PF14678", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14678" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "FANCI solenoid 4", "eco_id": "ECO_0000259", "start_pos": 1044, "end_pos": 1297, "start_aa": "Leu", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1121, "end_pos": 1123 }, { "start_pos": 1293, "end_pos": 1295 }, { "start_pos": 1316, "end_pos": 1318 }, { "start_pos": 478, "end_pos": 480 }, { "start_pos": 489, "end_pos": 491 }, { "start_pos": 765, "end_pos": 767 }, { "start_pos": 795, "end_pos": 797 }, { "start_pos": 949, "end_pos": 951 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 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"common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SPATA17", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YND7", "locus": { "chromosome": "3", "start_pos": 19225102, "end_pos": 19429859, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010016215", "url": "https://www.ensembl.org/id/ENSGALG00010016215" } ] } } ], "crossref": [ { "id": "A0A8V0YND7", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YND7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000009616", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000009616", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd23767", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd23767", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "421354", "url": "https://www.ncbi.nlm.nih.gov/gene/421354", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000048", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000048", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051185", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051185", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052318", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052318", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:421354", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:421354", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "LHTTSKY", "url": "https://omabrowser.org/oma/group/LHTTSKY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q2U587", "url": "https://www.orthodb.org/?gene=A0A3Q2U587", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YNC8", "url": "https://www.orthodb.org/?gene=A0A8V0YNC8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YND7", "url": "https://www.orthodb.org/?gene=A0A8V0YND7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YUT5", "url": "https://www.orthodb.org/?gene=A0A8V0YUT5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YWU5", "url": "https://www.orthodb.org/?gene=A0A8V0YWU5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z1K6", "url": "https://www.orthodb.org/?gene=A0A8V0Z1K6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z1L9", "url": "https://www.orthodb.org/?gene=A0A8V0Z1L9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1C170", "url": "https://www.orthodb.org/?gene=E1C170", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22590", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22590", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22590:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22590:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22706", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22706", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22706:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22706:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00612", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00612", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A3Q2U587", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U587", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2U587-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U587-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YNC8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNC8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YNC8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNC8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YND7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YND7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YND7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YND7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YUT5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUT5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YUT5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUT5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YWU5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YWU5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YWU5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YWU5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z1K6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1K6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z1K6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1K6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z1L9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1L9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z1L9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1L9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C170", "url": "https://www.uniprot.org/uniprotkb/E1C170", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C170-1", "url": "https://www.uniprot.org/uniprotkb/E1C170-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAALVRLETRLSRLREEYFLKNRSVDEDRKIVYKAAVKIQSWFRGCRVRAYLRYLNKMAISIQKWWRGYQSRRYFRKMIKTAYFIMKMNFYNEMAVRIQKRWRGYYVRKYTHNYYALKKYLEAISLNNEIVRNELQEYAEMNEKKKKKKDLEKKEKEKKYKARKMHYLLSTEQIAGIYNSPFRKFPDPMELLLRQSKPLSHRQQQPKSPFTYDLYDWPTCKRPPAFPTGEPLPPIGRQKPQGPFRDAAEVLRQRYKPLEPTLRVAASISSPLEKAREEMKREEWRKCIHDNEFLPFSSYHKNEKYELSIHASEKIGKETYGIKHFREVQPNKWIAGKIYLLHHCSSSFSLLIYILFEIHLFRGTVEVEFLYFLKMNCPTR", "length": 380, "header": "tr|A0A8V0YND7-1|A0A8V0YND7_CHICK Isoform 1 of Spermatosis associated 17 OS=Gallus gallus OX=9031 GN=SPATA17 PE=4 SV=1 CANONICAL=A0A8V0YND7-1" }, "isoforms": [ { "isoform_ac": "A0A3Q2U587-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YND7/entry#A0A3Q2U587-1", "sequence": { "sequence": "MAALVRLETRLSRLREEYFLKNRSVDEDRKIVYKAAVKIQSWFRGCRVRAYLRYLNKMAISIQKWWRGYQSRRYFRKMIKTAYFIMKMNFYNEMAVRIQKRWRGYYVRKYTHNYYALKKYLEAISLNNEIVRNELQEYAEMNEKKKKKKDLEKKEKEKKYKARKMHYLLSTEQIAGIYNSPFRKFPDPMELLLRQSKPLSHRQQQPKSPFTYDLYDWPTCKRPPAFPTGEPLPPIGRQKPQGPFRDAAEVLRQRYKPLEPTLRVAASISSPLEKAREEMKREEWRKCIHDNEFLPFSSYHKNEKYELSIHASEKIGKETYGIKHFREVQPNKWIAGKDFQTVLPSIVLFEKFGKTYSKAGQIV", "length": 363, "header": "tr|A0A3Q2U587-1|A0A3Q2U587_CHICK Computationally mapped isoform of Spermatosis associated 17 OS=Gallus gallus OX=9031 GN=SPATA17 PE=4 SV=1 CANONICAL=A0A8V0YND7-1" }, "locus": { "chromosome": "3", "start_pos": 19429816, "end_pos": 19340823, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010038958.1", "url": "https://www.ensembl.org/id/ENSGALT00010038958.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010022506.1", "url": "https://www.ensembl.org/id/ENSGALP00010022506.1" } ] } }, { "isoform_ac": "A0A8V0YNC8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YND7/entry#A0A8V0YNC8-1", "sequence": { "sequence": "MAALVRLETRLSRLREEYFLKNRSVDEDRKIVYKAAVKIQSWFRGCRVRAYLRYLNKMAISIQKWWRGYQSRRYFRKMIKTAYFIMKMNFYNEMAVRIQKRWRGYYVRKYTHNYYALKKYLEAISLNNEIVRNELQEYAEMNEKKKKKKDLEKKEKEKKYKARKMHYLLSTEQIAGIYNSPFRKFPDPMELLLRQSKPLSHRQQQPKSPFTYDLYDWPTCKRPPAFPTGEPLPPIGRQKPQGPFRDAAEVLRQRYKPLEPTLRVAASISSPLEKAREEMKREEWRKCIHDNEFLPFSSYHKNEKYELSIHASEKIGKETYGIKHFREVQPNKWIAGKV", "length": 338, "header": "tr|A0A8V0YNC8-1|A0A8V0YND7_CHICK Computationally mapped isoform of Spermatosis associated 17 OS=Gallus gallus OX=9031 GN=SPATA17 PE=4 SV=1 CANONICAL=A0A8V0YND7-1" }, "locus": { "chromosome": "3", "start_pos": 19429816, "end_pos": 19350155, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010038956.1", "url": "https://www.ensembl.org/id/ENSGALT00010038956.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010022505.1", "url": "https://www.ensembl.org/id/ENSGALP00010022505.1" } ] } }, { "isoform_ac": "A0A8V0YND7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YND7/entry#A0A8V0YND7-1", "sequence": { "sequence": "MAALVRLETRLSRLREEYFLKNRSVDEDRKIVYKAAVKIQSWFRGCRVRAYLRYLNKMAISIQKWWRGYQSRRYFRKMIKTAYFIMKMNFYNEMAVRIQKRWRGYYVRKYTHNYYALKKYLEAISLNNEIVRNELQEYAEMNEKKKKKKDLEKKEKEKKYKARKMHYLLSTEQIAGIYNSPFRKFPDPMELLLRQSKPLSHRQQQPKSPFTYDLYDWPTCKRPPAFPTGEPLPPIGRQKPQGPFRDAAEVLRQRYKPLEPTLRVAASISSPLEKAREEMKREEWRKCIHDNEFLPFSSYHKNEKYELSIHASEKIGKETYGIKHFREVQPNKWIAGKIYLLHHCSSSFSLLIYILFEIHLFRGTVEVEFLYFLKMNCPTR", "length": 380, "header": "tr|A0A8V0YND7-1|A0A8V0YND7_CHICK Isoform 1 of Spermatosis associated 17 OS=Gallus gallus OX=9031 GN=SPATA17 PE=4 SV=1 CANONICAL=A0A8V0YND7-1" }, "locus": { "chromosome": "3", "start_pos": 19429816, "end_pos": 19260959, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010038974.1", "url": "https://www.ensembl.org/id/ENSGALT00010038974.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010022515.1", "url": "https://www.ensembl.org/id/ENSGALP00010022515.1" } ] } }, { "isoform_ac": "A0A8V0YUT5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YND7/entry#A0A8V0YUT5-1", "sequence": { "sequence": "MAALVRLETRLSRLREEYFLKNRSVDEDRKIVYKAAVKIQSWFRGCRVRAYLRYLNKMAISIQKWWRGYQSRRYFRKMIKTAYFIMKMNFYNEMAVRIQKRWRGYYVRKYTHNYYALKKYLEAISLNNEIVRNELQEYAEMNEKKKKKKDLEKKEKEKKYKARKMHYLLSTEQIAGIYNSPFRKFPDPMELLLRQSKPLSHRQQQPKSPFTYDLYDWPTCKRPPAFPTGEPLPPIGRQKPQGPFRDAAEVLRQRYKPLEPTLRVAASISSPLEKAREEMKREEWRKCIHDNEFLPFSSYHKNEKYELSIHASEKIGKETYGIKHFREVQPNKWIAGK", "length": 337, "header": "tr|A0A8V0YUT5-1|A0A8V0YUT5_CHICK Computationally mapped isoform of Spermatosis associated 17 OS=Gallus gallus OX=9031 GN=SPATA17 PE=4 SV=1 CANONICAL=A0A8V0YND7-1" }, "locus": { "chromosome": "3", "start_pos": 19429816, "end_pos": 19363941, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010038968.1", "url": "https://www.ensembl.org/id/ENSGALT00010038968.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010022512.1", "url": "https://www.ensembl.org/id/ENSGALP00010022512.1" } ] } }, { "isoform_ac": "A0A8V0YWU5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YND7/entry#A0A8V0YWU5-1", "sequence": { "sequence": "MAALVRLETRLSRLREEYFLKNRSVDEDRKIVYKAAVKIQSWFRGCRVRAYLRYLNKMAISIQKWWRGYQSRRYFRKMIKTAYFIMKMNFYNEMAVRIQKRWRGYYVRKYTHNYYALKKYLEAISLNNEIVRNELQEYAEMNEKKKKKKDLEKKEKEKKYKARKMHYLLSTEQIAGIYNSPFRKFPDPMELLLRQSKPLSHRQQQPKSPFTYDLYDWPTCKRPPAFPTGEPLPPIGRQKPQGPFRDAAEVLRQRYKPLEPTLRVAASISSPLEKAREEMKREEWRKCIHDNEFLPFSSYHKNEKYELSIHASEKIGKETYGIKHFREVQPNKWIAGKNSCIS", "length": 342, "header": "tr|A0A8V0YWU5-1|A0A8V0YWU5_CHICK Computationally mapped isoform of Spermatosis associated 17 OS=Gallus gallus OX=9031 GN=SPATA17 PE=4 SV=1 CANONICAL=A0A8V0YND7-1" }, "locus": { "chromosome": "3", "start_pos": 19429816, "end_pos": 19260982, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010038979.1", "url": "https://www.ensembl.org/id/ENSGALT00010038979.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010022518.1", "url": "https://www.ensembl.org/id/ENSGALP00010022518.1" } ] } }, { "isoform_ac": "A0A8V0Z1K6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YND7/entry#A0A8V0Z1K6-1", "sequence": { "sequence": "MAALVRLETRLSRLREEYFLKNRSVDEDRKIVYKAAVKIQSWFRGCRVRAYLRYLNKMAISIQKWWRGYQSRRYFRKMIKTAYFIMKMNFYNEMAVRIQKRWRGYYVRKYTHNYYALKKYLEAISLNNEIVRNELQEYAEMNEKKKKKKDLEKKEKEKKYKARKMHYLLSTEQIAGIYNSPFRKFPDPMELLLRQSKPLSHRQQQPKSPFTYDLYDWPTCKRPPAFPTGEPLPPIGRQKPQGPFRDAAEVLRQRYKPLEPTLRVAASISSPLEKAREEMKREEWRKCIHDNEFLPFSSYHKNEKYELSIHASEKIGKETYGIKHFREVQPNKWIAGKVENLFSSRRTDISHKMLAYVSDEEEKQPAKKRFTFYFISWSTY", "length": 380, "header": "tr|A0A8V0Z1K6-1|A0A8V0Z1K6_CHICK Computationally mapped isoform of Spermatosis associated 17 OS=Gallus gallus OX=9031 GN=SPATA17 PE=4 SV=1 CANONICAL=A0A8V0YND7-1" }, "locus": { "chromosome": "3", "start_pos": 19429816, "end_pos": 19284090, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010038966.1", "url": "https://www.ensembl.org/id/ENSGALT00010038966.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010022511.1", "url": "https://www.ensembl.org/id/ENSGALP00010022511.1" } ] } }, { "isoform_ac": "A0A8V0Z1L9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YND7/entry#A0A8V0Z1L9-1", "sequence": { "sequence": "MAALVRLETRLSRLREEYFLKNRSVDEDRKIVYKAAVKIQSWFRGCRVRAYLRYLNKMAISIQKWWRGYQSRRYFRKMIKTAYFIMKMNFYNEMAVRIQKRWRGYYVRKYTHNYYALKKYLEAISLNNEIVRNELQEYAEMNEKKKKKKDLEKKEKEKKYKARKMHYLLSTEQIAGIYNSPFRKFPDPMELLLRQSKPLSHRQQQPKSPFTYDLYDWPTCKRPPAFPTGEPLPPIGRQKPQGPFRDAAEVLRQRYKPLEPTLRVAASISSPLEKAREEMKREEWRKCIHDNEFLPFSSYHKNEKYELSIHASEKIGKETYGIKHFREVQPNKWIAGKVSGFLLLKRAWSLRLML", "length": 354, "header": "tr|A0A8V0Z1L9-1|A0A8V0Z1L9_CHICK Computationally mapped isoform of Spermatosis associated 17 OS=Gallus gallus OX=9031 GN=SPATA17 PE=4 SV=1 CANONICAL=A0A8V0YND7-1" }, "locus": { "chromosome": "3", "start_pos": 19429816, "end_pos": 19225198, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010038984.1", "url": "https://www.ensembl.org/id/ENSGALT00010038984.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010022521.1", "url": "https://www.ensembl.org/id/ENSGALP00010022521.1" } ] } }, { "isoform_ac": "E1C170-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YND7/entry#E1C170-1", "sequence": { "sequence": "MAALVRLETRLSRLREEYFLKNRSVDEDRKIVYKAAVKIQSWFRGCRVRAYLRYLNKMAISIQKWWRGYQSRRYFRKMIKIQKRWRGYYVRKYTHNYYALKKYLEAISLNNEIVRNELQEYAEMNEKKKKKKDLEKKEKEKKYKARKMHYLLSTEQIAGIYNSPFRKFPDPMELLLRQSKPLSHRQQQPKSPFTYDLYDWPTCKRPPAFPTGEPLPPIGRQKPQGPFRDAAEVLRQRYKPLEPTLRVAASISSPLEKAREEMKREEWRKCIHDNEFLPFSSYHKNEKYELSIHASEKIGKETYGIKHFREVQPNKWIAGKDFQTVLPSIVLFEKFGKTYSKAGQIV", "length": 346, "header": "tr|E1C170-1|E1C170_CHICK Computationally mapped isoform of Spermatosis associated 17 OS=Gallus gallus OX=9031 GN=SPATA17 PE=4 SV=4 CANONICAL=A0A8V0YND7-1" }, "locus": { "chromosome": "3", "start_pos": 19429816, "end_pos": 19340823, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010038962.1", "url": "https://www.ensembl.org/id/ENSGALT00010038962.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010022508.1", "url": "https://www.ensembl.org/id/ENSGALP00010022508.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:421354", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:421354", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3Q1LVL8-1", "protein_name": "Spermatosis associated 17", "gene_name": "SPATA17", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MATLARLQARSKSIAQQYYYRNSVVDIFRKKENDAAIKIQSWFRGCQVRAYIRYLHRVATIIQKRWRGYLGRQQYQVIVKLAYYTMKMNLYNAMAVRIQRRWRGYKIRKYCFNYYYLKEYLKAVSETNDAIREALEEFAEMKEREEKKADLEREEKERDYQARKMHYLLSTKQIPGIYNSPFRKDPDPWELRLQKAKPLTHRRPEVKRKRSICLSDWLACTSARSFPRSGILPPIDRKRCQGPFRDISEVLEQRYKPLEPTLRVAEPIDGLTEARAQLQKQEWARNVNDNMFLPFSSYHKNKKYVPTMHLSSKYGPDVYGTQHFRDENPKRWICNKDFQTVLPSFDLFSKYGKMYSKAGQIV", "length": 362 }, "evidence": [ { "id": "A0A8V0YND7", "url": "https://omabrowser.org/oma/group/A0A8V0YND7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q96L03-1", "protein_name": "Spermatogenesis-associated protein 17", "gene_name": "SPATA17", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MATLARLQARSSTVGNQYYFRNSVVDPFRKKENDAAVKIQSWFRGCQVRAYIRHLNRIVTIIQKWWRSFLGRKQYQLTVQVAYYTMMMNLYNAMAVRIQRRWRGYRVRKYLFNYYYLKEYLKVVSETNDAIRKALEEFAEMKEREEKKANLEREEKKRDYQARKMHYLLSTKQIPGIYNSPFRKEPDPWELQLQKAKPLTHRRPKVKQKDSTSLTDWLACTSARSFPRSEILPPINRKQCQGPFRDITEVLEQRYRPLEPTLRVAEPIDELKLAREELRREEWLQNVNDNMFLPFSSYHKNEKYIPSMHLSSKYGPISYKEQFRSENPKKWICDKDFQTVLPSFELFSKYGKLYSKAGQIV", "length": 361 }, "evidence": [ { "id": "A0A8V0YND7", "url": "https://omabrowser.org/oma/group/A0A8V0YND7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9D552-1", "protein_name": "Spermatogenesis-associated protein 17", "gene_name": "Spata17", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "METNSNNFGELQELKDMATLAKLLARAPFLESQYYFRNRAVDSFRKFENDAAVMIQSWFRGCQVRAYMRHLNRVVTIIQKWWRSYLGRKFYQLVVEAAYYTMKMNLYNEMAVRIQRRWRGFRIRKYCFNYYYLKEYLRAVSETNDAIREALEEFAEMKEREERKVLLEREEKQKDYQARKMHYLLSTKQISGIYNSPFREHPDPWELRLQKAKPLGHQKYTAEKGKTSQSPSNWLACTSVHSFPQSESLPPISRKRCQGPFRDINEVLEQRYKPLEPTLRVAEPINHLRLAREAFKQEERMRNVQDKMFLPFSSYHKKEKYIPMIHSSSAYNSDSYGQKHFRSQDSKKWISDKDFQTVLPSFQLFSKYGKLYSKAGEIV", "length": 379 }, "evidence": [ { "id": "A0A8V0YND7", "url": "https://omabrowser.org/oma/group/A0A8V0YND7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "calmodulin binding", "id": "GO:0005516", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005516", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YND7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YND7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YND7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YND7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 22, "end_pos": 24, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 22, "end_pos": 24 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YNH9-1", "uniprot_ac": "A0A8V0YNH9", "uniprot_id": "A0A8V0YNH9_CHICK", "mass": { "chemical_mass": 102346.0, "monoisotopic_mass": 102346.0 }, "refseq": {}, "gene_names": [ { "name": "FIRRM", "type": "recommended", "evidence": [ { "id": "A0A8V0YNH9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNH9" } ] } ], "protein_names": [ { "name": "FIGNL1 interacting regulator of recombination and mitosis", "type": "synonym", "evidence": [ { "id": "A0A8V0YNH9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNH9/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNH9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNH9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "FIRRM", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNH9", "locus": { "chromosome": "8", "start_pos": 5071704, "end_pos": 5093048, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010014274", "url": "https://www.ensembl.org/id/ENSGALG00010014274" } ] } } ], "crossref": [ { "id": "A0A8V0YNH9", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YNH9", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR011989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027902", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027902", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YND8", "url": "https://www.orthodb.org/?gene=A0A8V0YND8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YNH9", "url": "https://www.orthodb.org/?gene=A0A8V0YNH9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YQ89", "url": "https://www.orthodb.org/?gene=A0A8V0YQ89", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YQ94", "url": "https://www.orthodb.org/?gene=A0A8V0YQ94", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16071", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16071", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16071:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16071:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF14868", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14868", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-2500257", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2500257", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-5693568", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5693568", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-912446", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-912446", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YND8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YND8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YND8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YND8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YNH9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNH9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YNH9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNH9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQ89", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ89", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQ89-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ89-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQ94", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ94", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQ94-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ94-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSQTDLELLLRELGGWDWELCRRELPAVLPRLLSMYQESEDWTEHIRVLRILTEMFLPHISLGDLEQTFFSKVLPKTLQLYDKLMYELSSEAKGLTGQNTELRSTVRNLLQTIVQLLETLTSCVRYICTLQECVPLDSIRTLPSSVLYVIKSTFTHCKDSESVYCGHLHLISDLLQAVFKETYSLQKQLMELFDQISVGPASTEDDITDMVSVIHTVLEICSVISNMDHALHANTWKFIIKQSLKHHALLQCHLKHSDILSGLCKDTLLSFHSSLQLAEEMKMSDIQDGADLRLFQKTVKLCRFFANSLVYYTKEFLPFLSDLCSQLHQLFLQIYSKFPPSLYAPVISEVHQDEISRVFLVALDPLISQLLPFSPFMEQVLRDTSGLPAEQQLPQCLLLITIMDKLSSQPEEVQTLWNTGKRLSFLSALFQSFQQCSAELSLPVCLPEVISTGQPAVPITLYHYVCVHLCSFIASTLPSQFPHLEYALLDAVLGSSMITSLLAMDSWCFLARYGTAELCAHHCVVIAHLIKSWPNECYQVSVLGVLLKRMLFLMAPDHQVEFAHKFLPEEVENLAVWQHVSLRALSPDLGKRVVRELCMAALAQCRRWLNSRRAWGELQPVNVAFSVLLVACNFSGDALEAELQASILGVLGQFWTFLQAKQVSDEPRLQQTLCLLLHLLEFFIQALDAQLISQVFSLLSSLLRLDPPDHIRLAMLDFLSSVGKVFIPQEVQRQVVPQLSCSFASLLADQTWLIHQRALEAFRHFAEETIHEDVVPQCLNSEEIKNKVVNFMAKVKQGEETTEARIERLKQERITCDAHFLKMARELESTGEPLAKRACHPPSEEQYKSAVGTMEGAVEAVKLLLQKGSPPAWVAAKLEALHTAITILRDSVRKQLLSCCTLAL", "length": 904, "header": "tr|A0A8V0YNH9-1|A0A8V0YNH9_CHICK Isoform 1 of FIGNL1 interacting regulator of recombination and mitosis OS=Gallus gallus OX=9031 GN=FIRRM PE=4 SV=1 CANONICAL=A0A8V0YNH9-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YND8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNH9/entry#A0A8V0YND8-1", "sequence": { "sequence": "MSQTDLELLLRELGGWDWELCRRELPAVLPRLLSMYQESEDWTEHIRVLRILTEMFLPHISLGDLEQTFFSKVLPKTLQLYDKLMYELSSEAKGLTGQNTELRSTVRNLLQTIVQLLETLTSCVRYICTLQECVPLDSIRTLPSSVLYVIKSTFTHCKDSESVYCGHLHLISDLLQAVFKETYSLQKQLMELFDQISVGPASTEDDITDMVSVIHTVLEICSVISNMDHALHANTWKFIIKQSLKHHALLQCHLKHSDILSGLCKDTLLSFHSSLQLAEEMKMSDIQDGADLRLFQKTVKLCRFFANSLVYYTKEFLPFLSDLCSQLHQLFLQIYSKFPPSLYAPVISEVHQDEISRVFLVALDPLISQLLPFSPFMEQVLRDTSGLPAEQQLPQCLLLITIMDKLSSQPEEVQTLWNTGKRLSFLSALFQSFQQCSAELSLPVCLPEVISTGQPAVPITLYHYVCVHLCSFIASTLPSQFPHLEYALLDAVLGSSMITSLLAMDSWCFLARYGTAELCAHHCVVIAHLIKSWPNECYQVSVLGVLLKRMLFLMAPDHQQVEFAHKFLPEEVENLAVWQHVSLRALSPDLGKRVVRELCMAALAQCRRWLNSRRAWGELQPVVKEVSDEPRLQQTLCLLLHLLEFFIQALDAQLISQVFSLLSSLLRLDPPDHIRLAMLDFLSSVGKVFIPQEVQRQVVPQLSCSFASLLADQTWLIHQRALEAFRHFAEETIHEDVVPQCLNSEEIKNKVVNFMAKVKQGEETTEARIERLKQERITCDAHFLKMARELESTGEPLAKRACHPPSEEQYKSAVGTMEGAVEAVKLLLQKGSPPAWVAAKLEALHTAITILRDSVR", "length": 856, "header": "tr|A0A8V0YND8-1|A0A8V0YNH9_CHICK Computationally mapped isoform of FIGNL1 interacting regulator of recombination and mitosis OS=Gallus gallus OX=9031 GN=FIRRM PE=4 SV=1 CANONICAL=A0A8V0YNH9-1" }, "locus": { "chromosome": "8", "start_pos": 5089749, "end_pos": 5074317, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034374.1", "url": "https://www.ensembl.org/id/ENSGALT00010034374.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020189.1", "url": "https://www.ensembl.org/id/ENSGALP00010020189.1" } ] } }, { "isoform_ac": "A0A8V0YNH9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNH9/entry#A0A8V0YNH9-1", "sequence": { "sequence": "MSQTDLELLLRELGGWDWELCRRELPAVLPRLLSMYQESEDWTEHIRVLRILTEMFLPHISLGDLEQTFFSKVLPKTLQLYDKLMYELSSEAKGLTGQNTELRSTVRNLLQTIVQLLETLTSCVRYICTLQECVPLDSIRTLPSSVLYVIKSTFTHCKDSESVYCGHLHLISDLLQAVFKETYSLQKQLMELFDQISVGPASTEDDITDMVSVIHTVLEICSVISNMDHALHANTWKFIIKQSLKHHALLQCHLKHSDILSGLCKDTLLSFHSSLQLAEEMKMSDIQDGADLRLFQKTVKLCRFFANSLVYYTKEFLPFLSDLCSQLHQLFLQIYSKFPPSLYAPVISEVHQDEISRVFLVALDPLISQLLPFSPFMEQVLRDTSGLPAEQQLPQCLLLITIMDKLSSQPEEVQTLWNTGKRLSFLSALFQSFQQCSAELSLPVCLPEVISTGQPAVPITLYHYVCVHLCSFIASTLPSQFPHLEYALLDAVLGSSMITSLLAMDSWCFLARYGTAELCAHHCVVIAHLIKSWPNECYQVSVLGVLLKRMLFLMAPDHQVEFAHKFLPEEVENLAVWQHVSLRALSPDLGKRVVRELCMAALAQCRRWLNSRRAWGELQPVNVAFSVLLVACNFSGDALEAELQASILGVLGQFWTFLQAKQVSDEPRLQQTLCLLLHLLEFFIQALDAQLISQVFSLLSSLLRLDPPDHIRLAMLDFLSSVGKVFIPQEVQRQVVPQLSCSFASLLADQTWLIHQRALEAFRHFAEETIHEDVVPQCLNSEEIKNKVVNFMAKVKQGEETTEARIERLKQERITCDAHFLKMARELESTGEPLAKRACHPPSEEQYKSAVGTMEGAVEAVKLLLQKGSPPAWVAAKLEALHTAITILRDSVRKQLLSCCTLAL", "length": 904, "header": "tr|A0A8V0YNH9-1|A0A8V0YNH9_CHICK Isoform 1 of FIGNL1 interacting regulator of recombination and mitosis OS=Gallus gallus OX=9031 GN=FIRRM PE=4 SV=1 CANONICAL=A0A8V0YNH9-1" }, "locus": { "chromosome": "8", "start_pos": 5089749, "end_pos": 5072708, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034381.1", "url": "https://www.ensembl.org/id/ENSGALT00010034381.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020192.1", "url": "https://www.ensembl.org/id/ENSGALP00010020192.1" } ] } }, { "isoform_ac": "A0A8V0YQ89-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNH9/entry#A0A8V0YQ89-1", "sequence": { "sequence": "MGVLRILTEMFLPHISLGDLEQTFFSKVLPKTLQLYDKLMYELSSEAKGLTGQNTELRSTVRNLLQTIVQLLETLTSCVRYICTLQECVPLDSIRTLPSSVLYVIKSTFTHCKDSESVYCGHLHLISDLLQAVFKETYSLQKQLMELFDQISVGPASTEDDITDMVSVIHTVLEICSVISNMDHALHANTWKFIIKQSLKHHALLQCHLKHSDILSGLCKDTLLSFHSSLQLAEEMKMSDIQDGADLRLFQKTVKLCRFFANSLVYYTKEFLPFLSDLCSQLHQLFLQIYSKFPPSLYAPVISEVHQDEISRVFLVALDPLISQLLPFSPFMEQVLRDTSGLPAEQQLPQCLLLITIMDKLSSQPEEVQTLWNTGKRLSFLSALFQSFQQCSAELSLPVCLPEVISTGQPAVPITLYHYVCVHLCSFIASTLPSQFPHLEYALLDAVLGSSMITSLLAMDSWCFLARYGTAELCAHHCVVIAHLIKSWPNECYQVSVLGVLLKRMLFLMAPDHQVEFAHKFLPEEVENLAVWQHVSLRALSPDLGKRVVRELCMAALAQCRRWLNSRRAWGELQPVNVAFSVLLVACNFSGDALEAELQASILGVLGQFWTFLQAKQVSDEPRLQQTLCLLLHLLEFFIQALDAQLISQVFSLLSSLLRLDPPDHIRLAMLDFLSSVGKVFIPQEVQRQVVPQLSCSFASLLADQTWLIHQRALEAFRHFAEETIHEDVVPQCLNSEEIKNKVVNFMAKVKQGEETTEARIERLKQERITCDAHFLKMARELESTGEPLAKRACHPPSEEQYKSAVGTMEGAVEAVKLLLQKGSPPAWVAAKLEALHTAITILRDSVR", "length": 848, "header": "tr|A0A8V0YQ89-1|A0A8V0YQ89_CHICK Computationally mapped isoform of FIGNL1 interacting regulator of recombination and mitosis OS=Gallus gallus OX=9031 GN=FIRRM PE=4 SV=1 CANONICAL=A0A8V0YNH9-1" }, "locus": { "chromosome": "8", "start_pos": 5088645, "end_pos": 5074317, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034370.1", "url": "https://www.ensembl.org/id/ENSGALT00010034370.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020188.1", "url": "https://www.ensembl.org/id/ENSGALP00010020188.1" } ] } }, { "isoform_ac": "A0A8V0YQ94-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNH9/entry#A0A8V0YQ94-1", "sequence": { "sequence": "MEEGVLRILTEMFLPHISLGDLEQTFFSKVLPKTLQLYDKLMYELSSEAKGLTGQNTELRSTVRNLLQTIVQLLETLTSCVRYICTLQECVPLDSIRTLPSSVLYVIKSTFTHCKDSESVYCGHLHLISDLLQAVFKETYSLQKQLMELFDQISVGPASTEDDITDMVSVIHTVLEICSVISNMDHALHANTWKFIIKQSLKHHALLQCHLKHSDILSGLCKDTLLSFHSSLQLAEEMKMSDIQDGADLRLFQKTVKLCRFFANSLVYYTKEFLPFLSDLCSQLHQLFLQIYSKFPPSLYAPVISEVHQDEISRVFLVALDPLISQLLPFSPFMEQVLRDTSGLPAEQQLPQCLLLITIMDKLSSQPEEVQTLWNTGKRLSFLSALFQSFQQCSAELSLPVCLPEVISTGQPAVPITLYHYVCVHLCSFIASTLPSQFPHLEYALLDAVLGSSMITSLLAMDSWCFLARYGTAELCAHHCVVIAHLIKSWPNECYQVSVLGVLLKRMLFLMAPDHQVEFAHKFLPEEVENLAVWQHVSLRALSPDLGKRVVRELCMAALAQCRRWLNSRRAWGELQPVNVAFSVLLVACNFSGDALEAELQASILGVLGQFWTFLQAKQVSDEPRLQQTLCLLLHLLEFFIQALDAQLISQVFSLLSSLLRLDPPDHIRLAMLDFLSSVGKVFIPQEVQRQVVPQLSCSFASLLADQTWLIHQRALEAFRHFAEETIHEDVVPQCLNSEEIKNKVVNFMAKVKQGEETTEARIERLKQERITCDAHFLKMARELESTGEPLAKRACHPPSEEQYKSAVGTMEGAVEAVKLLLQKGSPPAWVAAKLEALHTAITILRDSVR", "length": 850, "header": "tr|A0A8V0YQ94-1|A0A8V0YQ94_CHICK Computationally mapped isoform of FIGNL1 interacting regulator of recombination and mitosis OS=Gallus gallus OX=9031 GN=FIRRM PE=4 SV=1 CANONICAL=A0A8V0YNH9-1" }, "locus": { "chromosome": "8", "start_pos": 5091801, "end_pos": 5074317, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034386.1", "url": "https://www.ensembl.org/id/ENSGALT00010034386.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020193.1", "url": "https://www.ensembl.org/id/ENSGALP00010020193.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-2500257", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2500257", "resource": "Reactome", "description": "Resolution of Sister Chromatid Cohesion" }, { "id": "R-GGA-5693568", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5693568", "resource": "Reactome", "description": "Resolution of D-loop Structures through Holliday Junction Intermediates" }, { "id": "R-GGA-912446", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-912446", "resource": "Reactome", "description": "Meiotic recombination" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "mitotic cell cycle", "id": "GO:0000278", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000278", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNH9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNH9" } ], "pmid": "" }, { "name": "chromosome segregation", "id": "GO:0007059", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007059", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNH9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNH9" } ], "pmid": "" }, { "name": "interstrand cross-link repair", "id": "GO:0036297", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036297", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNH9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNH9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNH9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNH9" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNH9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNH9" } ], "pmid": "" }, { "name": "spindle midzone", "id": "GO:0051233", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051233", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNH9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNH9" } ], "pmid": "" }, { "name": "kinetochore", "id": "GO:0000776", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000776", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNH9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNH9" } ], "pmid": "" }, { "name": "midbody", "id": "GO:0030496", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030496", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNH9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNH9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "protein kinase binding", "id": "GO:0019901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019901", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNH9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNH9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 633, "end_pos": 635, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 633, "end_pos": 635 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": 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"n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YNE8-1", "uniprot_ac": "A0A8V0YNE8", "uniprot_id": "A0A8V0YNE8_CHICK", "mass": { "chemical_mass": 34088.0, "monoisotopic_mass": 34088.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Arrestin-like N-terminal domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A8V0YNE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNE8/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNE8", "url": 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"MTAVKAINLVLPEIKVCSTDSCVCGQLVLNLSSTLVDPVVKVELVGRGYLSCMTIACTNKAVYISKAKKFHICWAREECCLAFRQLPGFWDPHTFDFHFSFPPEVLCTFTSKVGCISYFVQGICCSHSTVLAKEQRYLLLQGISGDHMGHAKDKLRGTNCLKKHIFPGETVAFTTDIANRTCSYVKKVVFAICCTVLYRGFSNSGEQYSFEDQKEVMRLECQPGTSAFDTMRVISALVLPKPLPVTSALRGNYIMAFRHEQVETSNLPYATSTILGTVLIIIEQADCLSQRDLWEIPSAASMDGWAGG", "length": 308, "header": "tr|A0A8V0YNE8-1|A0A8V0YNE8_CHICK Isoform 1 of Arrestin-like N-terminal domain-containing protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0YNE8-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YNE8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNE8/entry#A0A8V0YNE8-1", "sequence": { "sequence": "MTAVKAINLVLPEIKVCSTDSCVCGQLVLNLSSTLVDPVVKVELVGRGYLSCMTIACTNKAVYISKAKKFHICWAREECCLAFRQLPGFWDPHTFDFHFSFPPEVLCTFTSKVGCISYFVQGICCSHSTVLAKEQRYLLLQGISGDHMGHAKDKLRGTNCLKKHIFPGETVAFTTDIANRTCSYVKKVVFAICCTVLYRGFSNSGEQYSFEDQKEVMRLECQPGTSAFDTMRVISALVLPKPLPVTSALRGNYIMAFRHEQVETSNLPYATSTILGTVLIIIEQADCLSQRDLWEIPSAASMDGWAGG", "length": 308, "header": "tr|A0A8V0YNE8-1|A0A8V0YNE8_CHICK Isoform 1 of Arrestin-like N-terminal domain-containing protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0YNE8-1" }, "locus": { "chromosome": "1", "start_pos": 30465159, "end_pos": 30459605, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032962.1", "url": "https://www.ensembl.org/id/ENSGALT00010032962.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019492.1", "url": "https://www.ensembl.org/id/ENSGALP00010019492.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 179, "end_pos": 181, "annotation": "n_glycosylation_sequon" }, { "start_pos": 30, "end_pos": 32, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 179, "end_pos": 181 }, { "start_pos": 30, "end_pos": 32 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YNG3-1", "uniprot_ac": "A0A8V0YNG3", "uniprot_id": "A0A8V0YNG3_CHICK", "mass": { "chemical_mass": 51814.0, "monoisotopic_mass": 51814.0 }, "refseq": { "ac": "XP_015149269", "name": "ras GTPase-activating protein-binding protein 1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015149269" }, "gene_names": [ { "name": "G3BP1", "type": "recommended", "evidence": [ { "id": "A0A8V0YNG3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNG3" } ] }, { "name": "G3BP1", "type": "synonym", "evidence": [ { "id": "XP_015149269", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015149269" } ] } ], "protein_names": [ { "name": "Ras GTPase-activating protein-binding protein 1", "type": "recommended", "evidence": [ { "id": "A0A8V0YNG3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNG3/entry#names_and_taxonomy" } ] }, { "name": "ras GTPase-activating protein-binding protein 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015149269", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015149269" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052544.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015149269", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015149269" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNG3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNG3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "G3BP1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNG3", "locus": { "chromosome": "13", "start_pos": 12484282, "end_pos": 12506960, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010014278", "url": "https://www.ensembl.org/id/ENSGALG00010014278" } ] } } ], "crossref": [ { "id": "A0A8V0YNG3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YNG3", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00780", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00780", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd12463", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12463", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "416265", "url": "https://www.ncbi.nlm.nih.gov/gene/416265", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000504", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000504", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002075", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002075", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012677", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012677", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018222", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018222", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032710", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032710", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034374", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034374", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039539", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039539", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YNG3", "url": "https://www.orthodb.org/?gene=A0A8V0YNG3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YQ99", "url": "https://www.orthodb.org/?gene=A0A8V0YQ99", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10693", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10693", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10693:SF21", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10693:SF21", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00076", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00076", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02136", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02136", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015149269", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015149269", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "13065", "url": "https://www.rhea-db.org/rhea/13065", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YNG3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNG3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YNG3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNG3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQ99", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ99", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQ99-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ99-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVMEKPSPLLVGREFVRQYYTLLNQAPDYLHRFYGKNSSYVHGGLDSNGKPADAVYGQSDIHKKVLSLNFKDCHTKIRHVDAHATLNDGVVVQVMGELSNNMQPVRRFMQTFVLAPEGSVANKFYVHNDIFRYQDEVFGDSDTEPPEESEEEGEEPEERQQTPEAVPDDTGAYYEQTVSNDIEEHLEETTAEAEPEPEPEPEQEPEPEAQEEKSEPVLEESAPEETVEKSPSPAPADPAPAVQEDSRTFSWASVTSKNLPPSGAVPVSGIPPHVVKVPVSQPRPEAKPESQTPPQRPQRDQRVREQRTSIPPQRGPRPIREGEQGDVETRRIVRYPDSHQLFVGNLPHDVDKSELKDFFQSYGNVVELRINSGGKLPNFGFVVFDDPDPVQKILSNRPIMFRGEVRLNVEEKKTRAAREGDRRDNRPRGPGGTRGGLGGGIRGPPRGGMSQKPGFGAGRGIGQRQ", "length": 465, "header": "tr|A0A8V0YNG3-1|A0A8V0YNG3_CHICK Isoform 1 of Ras GTPase-activating protein-binding protein 1 OS=Gallus gallus OX=9031 GN=G3BP1 PE=1 SV=1 CANONICAL=A0A8V0YNG3-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YNG3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNG3/entry#A0A8V0YNG3-1", "sequence": { "sequence": "MVMEKPSPLLVGREFVRQYYTLLNQAPDYLHRFYGKNSSYVHGGLDSNGKPADAVYGQSDIHKKVLSLNFKDCHTKIRHVDAHATLNDGVVVQVMGELSNNMQPVRRFMQTFVLAPEGSVANKFYVHNDIFRYQDEVFGDSDTEPPEESEEEGEEPEERQQTPEAVPDDTGAYYEQTVSNDIEEHLEETTAEAEPEPEPEPEQEPEPEAQEEKSEPVLEESAPEETVEKSPSPAPADPAPAVQEDSRTFSWASVTSKNLPPSGAVPVSGIPPHVVKVPVSQPRPEAKPESQTPPQRPQRDQRVREQRTSIPPQRGPRPIREGEQGDVETRRIVRYPDSHQLFVGNLPHDVDKSELKDFFQSYGNVVELRINSGGKLPNFGFVVFDDPDPVQKILSNRPIMFRGEVRLNVEEKKTRAAREGDRRDNRPRGPGGTRGGLGGGIRGPPRGGMSQKPGFGAGRGIGQRQ", "length": 465, "header": "tr|A0A8V0YNG3-1|A0A8V0YNG3_CHICK Isoform 1 of Ras GTPase-activating protein-binding protein 1 OS=Gallus gallus OX=9031 GN=G3BP1 PE=1 SV=1 CANONICAL=A0A8V0YNG3-1" }, "locus": { "chromosome": "13", "start_pos": 12495043, "end_pos": 12486784, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034415.1", "url": "https://www.ensembl.org/id/ENSGALT00010034415.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020209.1", "url": "https://www.ensembl.org/id/ENSGALP00010020209.1" } ] } }, { "isoform_ac": "A0A8V0YQ99-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNG3/entry#A0A8V0YQ99-1", "sequence": { "sequence": "MVMEKPSPLLVGREFVRQYYTLLNQAPDYLHRFYGKNSSYVHGGLDSNGKPADAVYGQSDIHKKVLSLNFKDCHTKIRHVDAHATLNDGVVVQVMGELSNNMQPVRRFMQTFVLAPEGSVANKFYVHNDIFRYQDEVFGDSDTEPPEESEEEGEEPEERQQTPEAVPDDTGAYYEQTVSNDIEEHLEETTAEAEPEPEPEPEQEPEPEAQEEKSEPVLEESAPEETVEKSPSPAPADPAPAVQEDSRTFSWASVTSKNLPPSGAVPVSGIPPHVVKVPVSQPRPEAKPESQTPPQRPQRDQRVREQRTSIPPQRGPRPIREGEQGDVETRRIVRYPDSHQLFVGNLPHDVDKSELKDFFQKLGSSLAGYGNVVELRINSGGKLPNFGFVVFDDPDPVQKILSNRPIMFRGEVRLNVEEKKTRAAREGDRRDNRPRGPGGGIRGPPRGGMSQKPGFGAGRGIGQRQ", "length": 465, "header": "tr|A0A8V0YQ99-1|A0A8V0YQ99_CHICK Computationally mapped isoform of G3BP stress granule assembly factor 1 OS=Gallus gallus OX=9031 GN=G3BP1 PE=1 SV=1 CANONICAL=A0A8V0YNG3-1" }, "locus": { "chromosome": "13", "start_pos": 12495043, "end_pos": 12486784, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034399.1", "url": "https://www.ensembl.org/id/ENSGALT00010034399.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020198.1", "url": "https://www.ensembl.org/id/ENSGALP00010020198.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 11, "go_terms": [ { "name": "DNA/RNA helicase activity", "id": "GO:0033677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033677", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNG3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNG3" } ], "pmid": "" }, { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNG3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNG3" } ], "pmid": "" }, { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNG3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNG3" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNG3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNG3" } ], "pmid": "" }, { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNG3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNG3" } ], "pmid": "" }, { "name": "ribosomal small subunit binding", "id": "GO:0043024", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043024", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNG3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNG3" } ], "pmid": "" }, { "name": "endonuclease activity", "id": "GO:0004519", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004519", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNG3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNG3" } ], "pmid": "" }, { "name": "DNA helicase activity", "id": "GO:0003678", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003678", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNG3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNG3" } ], "pmid": "" }, { "name": "RNA helicase activity", "id": "GO:0003724", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003724", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNG3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNG3" } ], "pmid": "" }, { "name": "molecular condensate scaffold activity", "id": "GO:0140693", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140693", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNG3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNG3" } ], "pmid": "" }, { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNG3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNG3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNG3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNG3" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNG3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNG3" } ], "pmid": "" }, { "name": "perikaryon", "id": "GO:0043204", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043204", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNG3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNG3" } ], "pmid": "" }, { "name": "cytoplasmic stress granule", "id": "GO:0010494", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010494", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNG3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNG3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "innate immune response", "id": "GO:0045087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045087", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNG3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNG3" } ], "pmid": "" }, { "name": "defense response to virus", "id": "GO:0051607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051607", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNG3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNG3" } ], "pmid": "" }, { "name": "stress granule assembly", "id": "GO:0034063", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034063", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNG3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNG3" } ], "pmid": "" }, { "name": "positive regulation of type I interferon production", "id": "GO:0032481", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032481", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNG3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNG3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 37, "end_pos": 39, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "13065", "name": "", "equation": "ATP + H2O = ADP + phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0ZC95-1", "A0A1D5PHB6-1", "A0A8V0XJV9-1", "A0A8V0ZFN9-1", "A0A1D5PIN7-1", "A0A8V0XT73-1", "A0A8V0XZB8-1", "A0A8V1AJ43-1", "A0A8V0ZU49-1", "P53478-1", "Q5F485-1", "Q5ZHZ0-1", "Q5ZI74-1", "Q5ZIW1-1", "Q5ZKB9-1", "Q5ZM36-1", "Q5ZMN2-1", "A0A8V0XLC7-1", "F1NFJ0-1", "A0A8V0YT68-1", "A0A1D5NTY5-1", "A0A8V0YU49-1", "A0A8V0YHC8-1", "A0A8V0ZPN6-1", "Q5ZJF6-1", "Q5ZKB7-1", "Q8JFP1-1", "A0A8V0YUW3-1", "Q5ZLN8-1", "E1BY42-1", "F1N8Z4-1", "F1NHI3-1", "A0A8V0XI26-1", "A0A8V0XEC4-1", "A0A8V0Y1J8-1", "A0A8V0Y242-1", "A0A8V0X9Z6-1", "A0A8V0Z289-1", "A0A8V0YFB8-1", "A0A8V0YFG2-1", "A0A8V0YNF9-1", "F1N991-1", "A0A8V0ZZF5-1", "A0A8V1ACD8-1", "A0A8V0ZUT3-1", "A0A8V0ZNU6-1", "A0A1D5P5I0-1", "A0A8V0ZZK3-1", "A0A8V1A3M1-1", "A0A8V1AJY9-1", "A0A8V1A712-1", "A0A8V1A7M6-1", "A0A3S5ZPN3-1", "A0A8V1A4V3-1", "A0A8V1AER6-1", "A0A8V1AL41-1", "A0A8V1A5D6-1", "A0A1D5PRR9-1", "A0A8V0Y0A4-1", "Q5ZKK7-1", "A0A8V1AFG8-1", "A0A8V0ZWH7-1", "A0A8V0YLM0-1", "A0A8V0ZNW3-1", "F1ND48-1", "F1NQJ3-1", "P08023-1", "P60706-1", "P63270-1", "P68034-1", "P68139-1", "Q5ZJT0-1", "Q5ZMQ2-1", "Q90593-1", "Q92058-1", "Q9I920-1", "Q90WU3-1", "A0A8V0ZVY2-1", "A0A8V0ZPM1-1", "Q3YK19-1", "E1BSC0-1", "A0A8V0X9Y7-1", "Q5ZM98-1", "F1NZ23-1", "A0A8V0YUG9-1", "F1NN44-1", "P08110-1", "F1NTD6-1", "A0A8V0Z655-1", "A0A8V1ALH0-1", "B6ZLK2-1", "A0A8V0YLC1-1", "Q06A37-1", "A0A8V0YGQ1-1", "A0A1D5PD32-1", "Q6EE31-1", "A0A8V0XX13-1", "A0A8V0YCY8-1", "A0A8V0Z5P2-1", "A0A8V0ZUQ0-1", "A0A8V1ADZ7-1", "A0A8V0XG98-1", "A0A8V0ZR10-1", "A0A8V1AFJ9-1", "Q5ZJ54-1", "Q5ZJK8-1", "A0A8V0Y005-1", "A0A8V0YAA4-1", "A0A8V0XGV3-1", "A0A8V0X600-1", "Q5ZM73-1", "Q5ZM83-1", "A0A8V0ZUR5-1", "A0A8V0ZE45-1", "A0A8V0ZEN5-1", "F1NA92-1", "A0A8V0ZTR5-1", "A0A8V1A7P4-1", "A0A8V1AIK2-1", "F1P5C0-1", "A0A8V0XHD1-1", "A0A8V0X655-1", "A0A8V0XMP8-1", "A0A8V0YUC5-1", "A0A8V0Z1F9-1", "A0A8V0Z659-1", "A0A8V0YRH6-1", "A0A8V0ZS56-1", "I0IUP3-1", "I0IUP4-1", "O93257-1", "O93295-1", "A0A8V0ZIP8-1", "Q9DG67-1", "P37383-1", "Q5ZKG3-1", "P79784-1", "A0A1D5PS27-1", "A0A1D5PVS9-1", "A0A8V1AE46-1", "A0A8V1A8Y2-1", "A0A8V1AKU6-1", "O12944-1", "A0A8V0YQS3-1", "A0A8V0Z2M8-1" ], "evidence": [ { "id": "13065", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/13065" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A1D5NTY5", "gene_name": "LOC430766", "activity": [ { "ec_number": "3.6.4.6", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5NTY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NTY5" } ] }, { "ec_number": "3.6.4.6", "activity": "", "evidence": [ { "id": "A0A1D5NTY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NTY5" } ] } ] }, { "uniprot_ac": "A0A1D5P5I0", "gene_name": "IFIH1", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5P5I0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P5I0" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A1D5P5I0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P5I0" } ] } ] }, { "uniprot_ac": "A0A1D5PD32", "gene_name": "DDX17", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5PD32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PD32" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A1D5PD32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PD32" } ] } ] }, { "uniprot_ac": "A0A1D5PHB6", "gene_name": "DHX36", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5PHB6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PHB6" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A1D5PHB6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PHB6" } ] } ] }, { "uniprot_ac": "A0A1D5PIN7", "gene_name": "DHX30", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5PIN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PIN7" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A1D5PIN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PIN7" } ] } ] }, { "uniprot_ac": "A0A1D5PRR9", "gene_name": "FANCM", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5PRR9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRR9" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A1D5PRR9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRR9" } ] } ] }, { "uniprot_ac": "A0A1D5PS27", "gene_name": "ENTPD2", "activity": [ { "ec_number": "3.6.1.5", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + 2 H2O = a 2'-deoxyribonucleoside 5'-phosphate + 2 phosphate + 2 H(+).", "evidence": [ { "id": "A0A1D5PS27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PS27" } ] }, { "ec_number": "3.6.1.5", "activity": "", "evidence": [ { "id": "A0A1D5PS27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PS27" } ] } ] }, { "uniprot_ac": "A0A1D5PVS9", "gene_name": "ENTPD3", "activity": [ { "ec_number": "3.6.1.5", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + 2 H2O = a 2'-deoxyribonucleoside 5'-phosphate + 2 phosphate + 2 H(+).", "evidence": [ { "id": "A0A1D5PVS9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PVS9" } ] }, { "ec_number": "3.6.1.5", "activity": "", "evidence": [ { "id": "A0A1D5PVS9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PVS9" } ] } ] }, { "uniprot_ac": "A0A3S5ZPN3", "gene_name": "DDX5", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A3S5ZPN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPN3" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A3S5ZPN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPN3" } ] } ] }, { "uniprot_ac": "A0A8V0X600", "gene_name": "DDX43", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0X600", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X600" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0X600", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X600" } ] } ] }, { "uniprot_ac": "A0A8V0X655", "gene_name": "DHX32", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0X655", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X655" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0X655", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X655" } ] } ] }, { "uniprot_ac": "A0A8V0X9Y7", "gene_name": "CFTR", "activity": [ { "ec_number": "5.6.1.6", "activity": "ATP + H2O + closed Cl(-) channel = ADP + phosphate + open Cl(-) channel.", "evidence": [ { "id": "A0A8V0X9Y7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X9Y7" } ] }, { "ec_number": "5.6.1.6", "activity": "", "evidence": [ { "id": "A0A8V0X9Y7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X9Y7" } ] } ] }, { "uniprot_ac": "A0A8V0X9Z6", "gene_name": "MOV10L1", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0X9Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X9Z6" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0X9Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X9Z6" } ] } ] }, { "uniprot_ac": "A0A8V0XEC4", "gene_name": "DDX10", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XEC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEC4" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0XEC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEC4" } ] } ] }, { "uniprot_ac": "A0A8V0XG98", "gene_name": "HELQ", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XG98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XG98" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "A0A8V0XG98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XG98" } ] } ] }, { "uniprot_ac": "A0A8V0XGV3", "gene_name": "DDX3X", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XGV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XGV3" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0XGV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XGV3" } ] } ] }, { "uniprot_ac": "A0A8V0XHD1", "gene_name": "AQR", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XHD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XHD1" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0XHD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XHD1" } ] } ] }, { "uniprot_ac": "A0A8V0XI26", "gene_name": "DDX1", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XI26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XI26" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0XI26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XI26" } ] } ] }, { "uniprot_ac": "A0A8V0XJV9", "gene_name": "SPATA5", "activity": [ { "ec_number": "3.6.4.6", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XJV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XJV9" } ] }, { "ec_number": "3.6.4.6", "activity": "", "evidence": [ { "id": "A0A8V0XJV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XJV9" } ] }, { "ec_number": "3.6.4.10", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XJV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XJV9" } ] }, { "ec_number": "3.6.4.10", "activity": "", "evidence": [ { "id": "A0A8V0XJV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XJV9" } ] } ] }, { "uniprot_ac": "A0A8V0XLC7", "gene_name": "MCM4", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XLC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XLC7" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "A0A8V0XLC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XLC7" } ] } ] }, { "uniprot_ac": "A0A8V0XMP8", "gene_name": "ZGRF1", "activity": [ { "ec_number": "5.6.2.3", "activity": "Couples ATP hydrolysis with the unwinding of duplex DNA at the replication fork by translocating in the 5'-3' direction.", "evidence": [ { "id": "A0A8V0XMP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMP8" } ] }, { "ec_number": "5.6.2.3", "activity": "", "evidence": [ { "id": "A0A8V0XMP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMP8" } ] } ] }, { "uniprot_ac": "A0A8V0XT73", "gene_name": "FBXO18", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XT73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XT73" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "A0A8V0XT73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XT73" } ] } ] }, { "uniprot_ac": "A0A8V0XX13", "gene_name": "LOC101748706", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XX13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XX13" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "A0A8V0XX13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XX13" } ] } ] }, { "uniprot_ac": "A0A8V0XZB8", "gene_name": "DHX34", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XZB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XZB8" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0XZB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XZB8" } ] } ] }, { "uniprot_ac": "A0A8V0Y005", "gene_name": "HSPA9", "activity": [ { "ec_number": "3.6.4.10", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0Y005", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y005" } ] }, { "ec_number": "3.6.4.10", "activity": "", "evidence": [ { "id": "A0A8V0Y005", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y005" } ] } ] }, { "uniprot_ac": "A0A8V0Y0A4", "gene_name": "AK6", "activity": [ { "ec_number": "2.7.4.3", "activity": "AMP + ATP = 2 ADP.", "evidence": [ { "id": "A0A8V0Y0A4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y0A4" } ] }, { "ec_number": "2.7.4.3", "activity": "", "evidence": [ { "id": "A0A8V0Y0A4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y0A4" } ] } ] }, { "uniprot_ac": "A0A8V0Y1J8", "gene_name": "YTHDC2", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0Y1J8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y1J8" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0Y1J8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y1J8" } ] } ] }, { "uniprot_ac": "A0A8V0Y242", "gene_name": "DDX41", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0Y242", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y242" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0Y242", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y242" } ] } ] }, { "uniprot_ac": "A0A8V0YAA4", "gene_name": "XRCC6", "activity": [ { "ec_number": "4.2.99.18", "activity": "2'-deoxyribonucleotide-(2'-deoxyribose 5'-phosphate)-2'-deoxyribonucleotide-DNA = a 3'-end 2'-deoxyribonucleotide-(2,3-dehydro-2,3-deoxyribose 5'-phosphate)-DNA + a 5'-end 5'-phospho-2'-deoxyribonucleoside-DNA + H(+).", "evidence": [ { "id": "A0A8V0YAA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAA4" } ] }, { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YAA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAA4" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "A0A8V0YAA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAA4" } ] }, { "ec_number": "4.2.99.18", "activity": "", "evidence": [ { "id": "A0A8V0YAA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAA4" } ] } ] }, { "uniprot_ac": "A0A8V0YCY8", "gene_name": "RIOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YCY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCY8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YCY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCY8" } ] } ] }, { "uniprot_ac": "A0A8V0YFB8", "gene_name": "ATP13A4", "activity": [ { "ec_number": "7.2.2.-", "activity": "", "evidence": [ { "id": "A0A8V0YFB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFB8" } ] } ] }, { "uniprot_ac": "A0A8V0YFG2", "gene_name": "ATP13A5", "activity": [ { "ec_number": "7.2.2.-", "activity": "", "evidence": [ { "id": "A0A8V0YFG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFG2" } ] } ] }, { "uniprot_ac": "A0A8V0YGQ1", "gene_name": "DDX59", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YGQ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGQ1" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0YGQ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGQ1" } ] } ] }, { "uniprot_ac": "A0A8V0YHC8", "gene_name": "VCP", "activity": [ { "ec_number": "3.6.4.6", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YHC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHC8" } ] }, { "ec_number": "3.6.4.6", "activity": "", "evidence": [ { "id": "A0A8V0YHC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHC8" } ] } ] }, { "uniprot_ac": "A0A8V0YLC1", "gene_name": "DDX11", "activity": [ { "ec_number": "5.6.2.3", "activity": "Couples ATP hydrolysis with the unwinding of duplex DNA at the replication fork by translocating in the 5'-3' direction.", "evidence": [ { "id": "A0A8V0YLC1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLC1" } ] }, { "ec_number": "5.6.2.3", "activity": "", "evidence": [ { "id": "A0A8V0YLC1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLC1" } ] } ] }, { "uniprot_ac": "A0A8V0YLM0", "gene_name": "RECQL", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YLM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLM0" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "A0A8V0YLM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLM0" } ] } ] }, { "uniprot_ac": "A0A8V0YNF9", "gene_name": "DDX27", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YNF9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNF9" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0YNF9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNF9" } ] } ] }, { "uniprot_ac": "A0A8V0YQS3", "gene_name": "MCM9", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YQS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQS3" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "A0A8V0YQS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQS3" } ] } ] }, { "uniprot_ac": "A0A8V0YRH6", "gene_name": "ERCC6L", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YRH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRH6" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "A0A8V0YRH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRH6" } ] } ] }, { "uniprot_ac": "A0A8V0YT68", "gene_name": "ATRX", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YT68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YT68" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "A0A8V0YT68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YT68" } ] } ] }, { "uniprot_ac": "A0A8V0YU49", "gene_name": "DHX29", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YU49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YU49" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0YU49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YU49" } ] } ] }, { "uniprot_ac": "A0A8V0YUC5", "gene_name": "SKIV2L2", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YUC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUC5" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0YUC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUC5" } ] } ] }, { "uniprot_ac": "A0A8V0YUG9", "gene_name": "TDRD9", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YUG9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUG9" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0YUG9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUG9" } ] } ] }, { "uniprot_ac": "A0A8V0YUW3", "gene_name": "EIF4A2", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YUW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUW3" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0YUW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUW3" } ] } ] }, { "uniprot_ac": "A0A8V0Z1F9", "gene_name": "DHX57", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0Z1F9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1F9" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0Z1F9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1F9" } ] } ] }, { "uniprot_ac": "A0A8V0Z289", "gene_name": "DDX24", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0Z289", "database": "UniProtKB", "url": 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"ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0Z655", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z655" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0Z655", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z655" } ] } ] }, { "uniprot_ac": "A0A8V0Z659", "gene_name": "TWNK", "activity": [ { "ec_number": "5.6.2.3", "activity": "Couples ATP hydrolysis with the unwinding of duplex DNA at the replication fork by translocating in the 5'-3' direction.", "evidence": [ { "id": "A0A8V0Z659", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z659" } ] }, { "ec_number": "5.6.2.3", "activity": "", "evidence": [ { "id": "A0A8V0Z659", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z659" } ] } ] }, { "uniprot_ac": "A0A8V0ZC95", "gene_name": "MCM6", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0ZC95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC95" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "A0A8V0ZC95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC95" } ] } ] }, { "uniprot_ac": "A0A8V0ZE45", "gene_name": "DDX42", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0ZE45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE45" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0ZE45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE45" } ] } ] }, { "uniprot_ac": "A0A8V0ZEN5", "gene_name": "DDX19", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0ZEN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEN5" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0ZEN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEN5" } ] } ] }, { "uniprot_ac": "A0A8V0ZFN9", "gene_name": "DDX54", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0ZFN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFN9" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0ZFN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFN9" } ] } ] }, { "uniprot_ac": "A0A8V0ZIP8", "gene_name": "XRCC5", "activity": [ { "ec_number": "4.2.99.18", "activity": "2'-deoxyribonucleotide-(2'-deoxyribose 5'-phosphate)-2'-deoxyribonucleotide-DNA = a 3'-end 2'-deoxyribonucleotide-(2,3-dehydro-2,3-deoxyribose 5'-phosphate)-DNA + a 5'-end 5'-phospho-2'-deoxyribonucleoside-DNA + H(+).", "evidence": [ { "id": "A0A8V0ZIP8", "database": "UniProtKB", "url": 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"https://www.uniprot.org/uniprotkb/A0A8V0ZNU6" } ] } ] }, { "uniprot_ac": "A0A8V0ZNW3", "gene_name": "ENTPD1", "activity": [ { "ec_number": "3.6.1.5", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + 2 H2O = a 2'-deoxyribonucleoside 5'-phosphate + 2 phosphate + 2 H(+).", "evidence": [ { "id": "A0A8V0ZNW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNW3" } ] }, { "ec_number": "3.6.1.5", "activity": "", "evidence": [ { "id": "A0A8V0ZNW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNW3" } ] } ] }, { "uniprot_ac": "A0A8V0ZPM1", "gene_name": "LOC121108097", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0ZPM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPM1" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0ZPM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPM1" } ] } ] }, { "uniprot_ac": "A0A8V0ZPN6", "gene_name": "INO80", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "A0A8V0ZPN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPN6" } ] } ] }, { "uniprot_ac": "A0A8V0ZR10", "gene_name": "PIF1", "activity": [ { "ec_number": "5.6.2.3", "activity": "Couples ATP hydrolysis with the unwinding of duplex DNA at the replication fork by translocating in the 5'-3' direction.", "evidence": [ { "id": "A0A8V0ZR10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR10" } ] }, { "ec_number": "5.6.2.3", "activity": "", "evidence": [ { "id": "A0A8V0ZR10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR10" } ] } ] }, { "uniprot_ac": "A0A8V0ZS56", "gene_name": "HFM1", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0ZS56", "database": "UniProtKB", "url": 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"activity": "", "evidence": [ { "id": "A0A8V0ZUR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUR5" } ] } ] }, { "uniprot_ac": "A0A8V0ZUT3", "gene_name": "DHX58", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0ZUT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUT3" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0ZUT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUT3" } ] } ] }, { "uniprot_ac": "A0A8V0ZVY2", "gene_name": "RTEL1", "activity": [ { "ec_number": "5.6.2.-", "activity": "", "evidence": [ { "id": "A0A8V0ZVY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVY2" } ] } ] }, { "uniprot_ac": "A0A8V0ZWH7", "gene_name": "DHX35", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0ZWH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWH7" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0ZWH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWH7" } ] } ] }, { "uniprot_ac": "A0A8V0ZZF5", "gene_name": "DHX8", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0ZZF5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZF5" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0ZZF5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZF5" } ] } ] }, { "uniprot_ac": "A0A8V0ZZK3", "gene_name": "SUPV3L1", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0ZZK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZK3" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0ZZK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZK3" } ] } ] }, { "uniprot_ac": "A0A8V1A3M1", "gene_name": "DDX55", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V1A3M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3M1" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V1A3M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3M1" } ] } ] }, { "uniprot_ac": "A0A8V1A4V3", "gene_name": "POLQ", "activity": [ { "ec_number": "2.7.7.7", "activity": "DNA(n) + a 2'-deoxyribonucleoside 5'-triphosphate = DNA(n+1) + diphosphate.", "evidence": [ { "id": "A0A8V1A4V3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4V3" } ] }, { "ec_number": "2.7.7.49", "activity": "DNA(n) + a 2'-deoxyribonucleoside 5'-triphosphate = DNA(n+1) + diphosphate.", "evidence": [ { "id": "A0A8V1A4V3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4V3" } ] }, { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V1A4V3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4V3" } ] }, { "ec_number": "2.7.7.7", "activity": "", "evidence": [ { "id": "A0A8V1A4V3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4V3" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "A0A8V1A4V3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4V3" } ] }, { "ec_number": "2.7.7.49", "activity": "", "evidence": [ { "id": "A0A8V1A4V3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4V3" } ] } ] }, { "uniprot_ac": "A0A8V1A5D6", "gene_name": "DDX51", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V1A5D6", "database": 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"id": "A0A8V1AFG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFG8" } ] } ] }, { "uniprot_ac": "A0A8V1AFJ9", "gene_name": "MCM2", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V1AFJ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFJ9" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "A0A8V1AFJ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFJ9" } ] } ] }, { "uniprot_ac": "A0A8V1AIK2", "gene_name": "DDX25", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V1AIK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIK2" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V1AIK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIK2" } ] } ] }, { "uniprot_ac": "A0A8V1AJ43", "gene_name": "DHX40", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V1AJ43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ43" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V1AJ43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ43" } ] } ] }, { "uniprot_ac": "A0A8V1AJY9", "gene_name": "DDX31", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V1AJY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJY9" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V1AJY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJY9" } ] } ] }, { "uniprot_ac": "A0A8V1AKU6", "gene_name": "HELZ", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V1AKU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKU6" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V1AKU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKU6" } ] } ] }, { "uniprot_ac": "A0A8V1AL41", "gene_name": "DHX33", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V1AL41", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL41" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V1AL41", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL41" } ] } ] }, { "uniprot_ac": "A0A8V1ALH0", "gene_name": "RNF213", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor 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"activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BY42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BY42" } ] }, { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BY42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BY42" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "E1BY42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BY42" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "E1BY42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BY42" } ] } ] }, { "uniprot_ac": "F1N8Z4", "gene_name": "RUVBL1", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1N8Z4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N8Z4" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "F1N8Z4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N8Z4" } ] } ] }, { "uniprot_ac": "F1N991", "gene_name": "DDX4", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1N991", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N991" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1N991", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N991" } ] } ] }, { "uniprot_ac": "F1NA92", "gene_name": "CLPX", "activity": [ { "ec_number": "3.6.4.10", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1NA92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NA92" } ] }, { "ec_number": "3.6.4.10", "activity": "", "evidence": [ { "id": "F1NA92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NA92" } ] } ] }, { "uniprot_ac": "F1ND48", "gene_name": 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"https://www.uniprot.org/uniprotkb/A0A8V0YNI5/entry#names_and_taxonomy" } ] }, { "name": "2.7.11.1", "type": "synonym", "evidence": [ { "id": "A0A8V0YNI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNI5/entry#names_and_taxonomy" } ] }, { "name": "NIM1 serine/threonine-protein kinase", "type": "synonym", "evidence": [ { "id": "A0A8V0YNI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNI5/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNI5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNI5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "NIM1K", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNI5", "locus": { "chromosome": "Z", "start_pos": 14190637, "end_pos": 14176926, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010014292", "url": "https://www.ensembl.org/id/ENSGALG00010014292" } ] } } ], "crossref": [ { "id": "A0A8V0YNI5", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YNI5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000014861", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000014861", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd14075", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14075", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "768482", "url": "https://www.ncbi.nlm.nih.gov/gene/768482", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000719", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000719", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008271", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008271", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011009", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011009", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017441", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017441", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR049571", "url": "https://www.ebi.ac.uk/interpro/entry/IPR049571", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:768482", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:768482", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "IMSNEWM", "url": "https://omabrowser.org/oma/group/IMSNEWM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YNI5", "url": "https://www.orthodb.org/?gene=A0A8V0YNI5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1C6B4", "url": "https://www.orthodb.org/?gene=E1C6B4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24346", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24346", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24346:SF49", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24346:SF49", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00069", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00069", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "17989", "url": "https://www.rhea-db.org/rhea/17989", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "46608", "url": "https://www.rhea-db.org/rhea/46608", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YNI5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNI5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YNI5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNI5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C6B4", "url": "https://www.uniprot.org/uniprotkb/E1C6B4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C6B4-1", "url": "https://www.uniprot.org/uniprotkb/E1C6B4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNQRKTQCSAFGLVPESGATFLSVCYVRDCILTEKYFTSLNSLLGHFVQWRSDYLQTMTTGFVNGGGLGKHRYARWNREDSGEDYGREECCGGDEEGRQQRLTPLEKLMQDMSHNEKVVKELTLGKRIGFYRVRGEIGSGNFSQVKLGIHSLTKEKVAIKILDKTKLDQKTQRLLSREISSMEKLHHPNIIRLYEVVETLSKLHLVMEYAGGGELFTKITTEGKLIETDCKIIFSQIVSAVKHMHENNIIHRDLKAENVFYTSNTCVKVGDFGFSTISKRDETLNTFCGSPPYAAPELFRDENYVGIYVDIWALGILLYFMITGIMPFRADTVAKLKKCILEGTYSLPPCLSEACQKLIKGVLQPVPTERYSVKLIMNSEWMQGIQYPKPLQPFKLDPKYLSEISTLKEEEIEVKNALKDLGITEEHIKNNQGRDARSSITGVYRIVLHKVQKKRALECVPIMSHPDPKEQDIKKGISSCNGVKHTSKLCSIL", "length": 493, "header": "tr|A0A8V0YNI5-1|A0A8V0YNI5_CHICK Isoform 1 of Serine/threonine-protein kinase NIM1 OS=Gallus gallus OX=9031 GN=NIM1K PE=3 SV=1 CANONICAL=A0A8V0YNI5-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YNI5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNI5/entry#A0A8V0YNI5-1", "sequence": { "sequence": "MNQRKTQCSAFGLVPESGATFLSVCYVRDCILTEKYFTSLNSLLGHFVQWRSDYLQTMTTGFVNGGGLGKHRYARWNREDSGEDYGREECCGGDEEGRQQRLTPLEKLMQDMSHNEKVVKELTLGKRIGFYRVRGEIGSGNFSQVKLGIHSLTKEKVAIKILDKTKLDQKTQRLLSREISSMEKLHHPNIIRLYEVVETLSKLHLVMEYAGGGELFTKITTEGKLIETDCKIIFSQIVSAVKHMHENNIIHRDLKAENVFYTSNTCVKVGDFGFSTISKRDETLNTFCGSPPYAAPELFRDENYVGIYVDIWALGILLYFMITGIMPFRADTVAKLKKCILEGTYSLPPCLSEACQKLIKGVLQPVPTERYSVKLIMNSEWMQGIQYPKPLQPFKLDPKYLSEISTLKEEEIEVKNALKDLGITEEHIKNNQGRDARSSITGVYRIVLHKVQKKRALECVPIMSHPDPKEQDIKKGISSCNGVKHTSKLCSIL", "length": 493, "header": "tr|A0A8V0YNI5-1|A0A8V0YNI5_CHICK Isoform 1 of Serine/threonine-protein kinase NIM1 OS=Gallus gallus OX=9031 GN=NIM1K PE=3 SV=1 CANONICAL=A0A8V0YNI5-1" }, "locus": { "chromosome": "Z", "start_pos": 14188296, "end_pos": 14179689, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034400.1", "url": "https://www.ensembl.org/id/ENSGALT00010034400.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020197.1", "url": "https://www.ensembl.org/id/ENSGALP00010020197.1" } ] } }, { "isoform_ac": "E1C6B4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNI5/entry#E1C6B4-1", "sequence": { "sequence": "MTTGFVNGGGLGKHRYARWNREDSGEDYGREECCGGDEEGRQQRLTPLEKLMQDMSHNEKVVKELTLGKRIGFYRVRGEIGSGNFSQVKLGIHSLTKEKVAIKILDKTKLDQKTQRLLSREISSMEKLHHPNIIRLYEVVETLSKLHLVMEYAGGGELFTKITTEGKLIETDCKIIFSQIVSAVKHMHENNIIHRDLKAENVFYTSNTCVKVGDFGFSTISKRDETLNTFCGSPPYAAPELFRDENYVGIYVDIWALGILLYFMITGIMPFRADTVAKLKKCILEGTYSLPPCLSEACQKLIKGVLQPVPTERYSVKLIMNSEWMQGIQYPKPLQPFKLDPKYLSEISTLKEEEIEVKNALKDLGITEEHIKNNQGRDARSSITGVYRIVLHKVQKKRALECVPIMSHPDPKEQDIKKGISSCNGVKHTSKLCSIL", "length": 436, "header": "tr|E1C6B4-1|E1C6B4_CHICK Computationally mapped isoform of Serine/threonine-protein kinase NIM1 OS=Gallus gallus OX=9031 GN=NIM1K PE=3 SV=1 CANONICAL=A0A8V0YNI5-1" }, "locus": { "chromosome": "Z", "start_pos": 14188296, "end_pos": 14180260, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034402.1", "url": "https://www.ensembl.org/id/ENSGALT00010034402.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020200.1", "url": "https://www.ensembl.org/id/ENSGALP00010020200.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "gga:768482", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:768482", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D4A9H8-1", "protein_name": "Serine/threonine-protein kinase NIM1", "gene_name": "Nim1k", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTAVVVNGGGLVNTHCDRWDRRDSAEGSCQTEGSKDGEEDQPRQLTPFEKLTQDMCQDEKVVREITLGKRIGFYRIRGEIGSGNFSQVKLGIHSLTKEKVAIKILDKTKLDQKTQRLLSREISSMEKLHHPNIVRLYEVVETLSKLHLVMEYAGGGELFGKISTEGKLSEPESKLIFSQIVSAVKHMHENQIIHRDLKAENVFYTSSTCVKVGDFGFSTVSKKGEMLNTFCGSPPYAAPELFRDEHYVGVYVDIWALGVLLYFMVTGTMPFRAETVAKLKKSILEGAYSIPQHVSEPCHRLIRGVLQPTPAERYGINYIMSNEWMRGVPYPSPLEPFQLDPKHLSETSTLKEEENEVKSTLEHLGITDEHIRNNQGRDARSSITGVYRIILHRVQRRKALESVPMATLPEPKDKDLKKGSRVYRGIRHTSKFCSIL", "length": 436 }, "evidence": [ { "id": "A0A8V0YNI5", "url": "https://omabrowser.org/oma/group/A0A8V0YNI5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E1BN72-1", "protein_name": "Serine/threonine-protein kinase NIM1", "gene_name": "NIM1K", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MTAVYVNGGGLVNPHCARWGRRESEESGCQTECAKEDEEGEPRQLTPFEKLTQDMSQDEKVVREITLGKRIGFYRIRGEIGSGNFSQVKLGIHSLTKEKVAIKILDKTKLDQKTQRLLSREISSMEKLHHPNIIRLYEVVETLSKLHLVMEYAGGGELFGKISMEGKFSEPESKLIFSQIVSAVKHMHENQIIHRDLKAENVFYTNNTCVKVGDFGFSTVSKKGEMLNTFCGSPPYAAPELFRDEHYVGVYVDIWALGVLLYFMVTGTMPFRAETVAKLKKSILEGTYSVPPHVSEPCLRLIRGVLQPVPAERYGIDSIMNNEWMQGVPYPTPLEPFQLDPKHLSETSSLKEEENEVKSTLEHLGITEEHIRNNQGRDARSSITGVYRIILHRVQKKKALESVPIMILPDPKDKDLKKGSRVYRGIRHTSKFCSIL", "length": 436 }, "evidence": [ { "id": "A0A8V0YNI5", "url": "https://omabrowser.org/oma/group/A0A8V0YNI5/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1SMG7-1", "protein_name": "Serine/threonine-protein kinase NIM1", "gene_name": "NIM1K", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MMTAVYVNGGSLVNSHYARWDRRESVESGCQTECNKEDEEGQPRQLTPFEKLMQDMSQDEKVVREITLGKRIGFYRIRGEIGSGNFSQVKLGIHSLTKEKVAIKILDKTKLDQKTQRLLSREISSMEKLHHPNIIRLYEVVETLSKLHLVMEYAGGGELFGKISTEGKFSESESKLIFSQIVSAVKHMHENQIIHRDLKAENVFYTSNTCVKVGDFGFSTVSKKGEMLNTFCGSPPYAAPELFRDEHYVGIYVDIWALGVLLYFMVTGTMPFRAETVAKLKKSILEGTYSVPPHVSEPCLRLIRGVLQPVPTERYGIDSIMNNEWMQGVPYPTPLEPFQLDPKHLSETSTLKEEENEVKSTLEHLGITEEHIRNNQGRDARSSITGVYRIILHRVQKKKALESVPIMILPDPKERDLKKGSRVYRGIRHTSKFCSIL", "length": 437 }, "evidence": [ { "id": "A0A8V0YNI5", "url": "https://omabrowser.org/oma/group/A0A8V0YNI5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3HMY1-1", "protein_name": "Serine/threonine-protein kinase NIM1", "gene_name": "Nim1k", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MTAVFANGGGLVNTHCDRWDRRDSVESSCQTECGQEGEEDQPRQLTPFEKLTQDMCQDEKVVREITLGKRIGFYRIRGEIGSGNFSQVKLGIHSLTKEKVAIKILDKTKLDQKTQRLLSREISSMEKLHHPNIIRLYEVVETLSKLHLVMEYAGGGELFGKISTEGKLSEPESKLIFSQIVSAVKHMHENQIIHRDLKAENVFYTSSTCVKVGDFGFSTVSKKGEMLNTFCGSPPYAAPELFRDEHYIGVYVDIWALGVLLYFMVTGTMPFRAETVAKLKKSILEGTYSIPQHVSEPCHRLIRGVLQPIPTERYGISYIMNNEWMRGVPYPTPLQPFQLDPKHLSEASSLEEEENEVKSTLEHLGITDEHIRNNPGRDARSSITGVYRIILHRVQRKKALESVPIMILPEPKERDLKKGSRIYRGIRHTSKFCSIL", "length": 436 }, "evidence": [ { "id": "A0A8V0YNI5", "url": "https://omabrowser.org/oma/group/A0A8V0YNI5/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q8BHI9-1", "protein_name": "Serine/threonine-protein kinase NIM1", "gene_name": "Nim1k", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTAVFVNGGGLVNTHCDRWERRDSVESSCQTEGGKDSEEDQQRQLTPFEKLTQDMCQDEKVVREITLGKRIGFYRIRGEIGSGNFSQVKLGIHSLTKEKVAIKILDKTKLDQKTQRLLSREISSMEKLHHPNIVRLYEVVETLSKLHLVMEYAGGGELFGKISTEGKLSEPESKLIFSQILSAVKHMHENQIIHRDLKAENVFYTSRTCVKVGDFGFSTVSKKGEMLNTFCGSPPYAAPELFRDQHYVGVYVDIWALGVLLYFMVTGTMPFRAETVAKLKKSILEGTYTIPQHVSEPCHRLIRGVLQPTPTERYGINYIMSNEWMRGVPYPTPLEPFQLDPKHLSETSTLKEEENEVKSTLEHLGITDEHIRNNQGRDARSSITGVYRIILHRVQRRKALESVPIMILPEPKERDLKKGSRIYRGIRHTSKFCSIL", "length": 436 }, "evidence": [ { "id": "A0A8V0YNI5", "url": "https://omabrowser.org/oma/group/A0A8V0YNI5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8IY84-1", "protein_name": "Serine/threonine-protein kinase NIM1", "gene_name": "NIM1K", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTAVYMNGGGLVNPHYARWDRRDSVESGCQTESSKEGEEGQPRQLTPFEKLTQDMSQDEKVVREITLGKRIGFYRIRGEIGSGNFSQVKLGIHSLTKEKVAIKILDKTKLDQKTQRLLSREISSMEKLHHPNIIRLYEVVETLSKLHLVMEYAGGGELFGKISTEGKLSEPESKLIFSQIVSAVKHMHENQIIHRDLKAENVFYTSNTCVKVGDFGFSTVSKKGEMLNTFCGSPPYAAPELFRDEHYIGIYVDIWALGVLLYFMVTGTMPFRAETVAKLKKSILEGTYSVPPHVSEPCHRLIRGVLQQIPTERYGIDCIMNDEWMQGVPYPTPLEPFQLDPKHLSETSTLKEEENEVKSTLEHLGITEEHIRNNQGRDARSSITGVYRIILHRVQRKKALESVPVMMLPDPKERDLKKGSRVYRGIRHTSKFCSIL", "length": 436 }, "evidence": [ { "id": "A0A8V0YNI5", "url": "https://omabrowser.org/oma/group/A0A8V0YNI5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "magnesium ion binding", "id": "GO:0000287", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000287", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNI5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNI5" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNI5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNI5" } ], "pmid": "" }, { "name": "tau-protein kinase activity", "id": "GO:0050321", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050321", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNI5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNI5" } ], "pmid": "" }, { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNI5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNI5" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNI5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNI5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNI5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNI5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "intracellular signal transduction", "id": "GO:0035556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035556", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNI5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNI5" } ], "pmid": "" }, { "name": "microtubule cytoskeleton organization", "id": "GO:0000226", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000226", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNI5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNI5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 141, "end_pos": 143, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "17989", "name": "", "equation": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q6U1I9-1", "A0A8V0XNJ2-1", "A0A8V0ZUL0-1", "A0A8V0ZT63-1", "A0A8V1ACW2-1", "A0A8V0Z1X0-1", "A0A8V0YHN2-1", "A0A8V0YMN5-1", "A0A8V0Z807-1", "A0A8V0Z930-1", "A0A8V0YFR6-1", "A0A1D5P0M9-1", "A0A8V0ZBN6-1", "A0A3Q2U9U9-1", "A0A8V0YXZ5-1", "A0A8V0ZSP4-1", "A0A8V0ZXQ9-1", "A0A8V0ZZV3-1", "A0A8V1ADF0-1", "A0A8V0ZFT3-1", "A0A8V0ZA45-1", "A0A8V0ZB33-1", "A0A8V0ZD70-1", "A0A8V0Z8T4-1", "R4GIN8-1", "A0A8V0ZK64-1", "A0A8V0ZC16-1", "A0A8V0ZWW1-1", "E1BY69-1", "A0A8V0ZDW9-1", "A0A8V0ZKA2-1", "A0A3Q3B2F1-1", "F1P356-1", "A0A8V1AHA8-1", "Q8QFP8-1", "F1P011-1", "A0A8V0YKK3-1", "A0A1D5NWT4-1", "A0A1D5PMQ7-1", "E1BWA3-1", "F1NVF2-1", "A0A1D5PXN4-1", "A0A3Q2TY19-1", "A0A3Q2U592-1", "A0A8V0XCV5-1", "A0A1D5P8A9-1", "A0A1D5PMG2-1", "A0A8V0X1Q7-1", 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O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XEA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEA3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XEA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEA3" } ] } ] }, { "uniprot_ac": "A0A8V0XFW1", "gene_name": "SGK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XFW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XFW1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XFW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XFW1" } ] } ] }, { "uniprot_ac": "A0A8V0XFX2", "gene_name": "NEK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": 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"ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0XLV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XLV6" } ] } ] }, { "uniprot_ac": "A0A8V0XMT1", "gene_name": "MOS", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XMT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMT1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XMT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMT1" } ] } ] }, { "uniprot_ac": "A0A8V0XMX8", "gene_name": "MASTL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XMX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMX8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": 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"ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YDH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDH4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YDH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDH4" } ] } ] }, { "uniprot_ac": "A0A8V0YF83", "gene_name": "WNK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YF83", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF83" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YF83", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF83" } ] } ] }, { "uniprot_ac": "A0A8V0YFH4", "gene_name": "NRK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YFH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFH4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YFH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFH4" } ] } ] }, { "uniprot_ac": "A0A8V0YFL1", "gene_name": "CDK19", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YFL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFL1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0YFL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFL1" } ] } ] }, { "uniprot_ac": "A0A8V0YFP8", "gene_name": "RIPK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YFP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFP8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YFP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFP8" } ] } ] }, { "uniprot_ac": "A0A8V0YFR6", "gene_name": "TNIK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YFR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFR6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YFR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFR6" } ] } ] }, { "uniprot_ac": "A0A8V0YGW2", "gene_name": "STK32B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YGW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGW2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YGW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGW2" } ] } ] }, { "uniprot_ac": "A0A8V0YHH2", "gene_name": "STK38L", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YHH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHH2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YHH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHH2" } ] } ] }, { "uniprot_ac": "A0A8V0YHN2", "gene_name": "RPS6KA1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YHN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHN2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YHN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHN2" } ] } ] }, { "uniprot_ac": "A0A8V0YIV6", "gene_name": "DYRK1A", "activity": [ { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] }, { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] } ] }, { "uniprot_ac": "A0A8V0YJP9", "gene_name": "RIOK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YJP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJP9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YJP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJP9" } ] } ] }, { "uniprot_ac": "A0A8V0YK18", "gene_name": "CDC42BPB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YK18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK18" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YK18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK18" } ] } ] }, { "uniprot_ac": "A0A8V0YKK3", "gene_name": "MAP4K4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YKK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKK3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YKK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKK3" } ] } ] }, { "uniprot_ac": "A0A8V0YLV1", "gene_name": "MARK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YLV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLV1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YLV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLV1" } ] } ] }, { "uniprot_ac": "A0A8V0YM22", "gene_name": "MYO3AL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YM22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM22" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YM22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM22" } ] } ] }, { "uniprot_ac": "A0A8V0YM96", "gene_name": "STK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YM96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM96" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YM96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM96" } ] } ] }, { "uniprot_ac": "A0A8V0YMB3", "gene_name": "STK32A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YMB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMB3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YMB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMB3" } ] } ] }, { "uniprot_ac": "A0A8V0YMN5", "gene_name": "BRAF", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YMN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMN5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YMN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMN5" } ] } ] }, { "uniprot_ac": "A0A8V0YNI5", "gene_name": "NIM1K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YNI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNI5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YNI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNI5" } ] } ] }, { "uniprot_ac": "A0A8V0YRC9", "gene_name": "TNK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YRC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRC9" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YRC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRC9" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0YRC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRC9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YRC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRC9" } ] } ] }, { "uniprot_ac": "A0A8V0YRN4", "gene_name": "GAK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YRN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRN4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YRN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRN4" } ] } ] }, { "uniprot_ac": "A0A8V0YSH3", "gene_name": "RPS6KA6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YSH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSH3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YSH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSH3" } ] } ] }, { "uniprot_ac": "A0A8V0YTI1", "gene_name": "TSSK6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTI1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTI1" } ] } ] }, { "uniprot_ac": "A0A8V0YTL9", "gene_name": "VRK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTL9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTL9" } ] } ] }, { "uniprot_ac": "A0A8V0YTN5", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTN5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTN5" } ] } ] }, { "uniprot_ac": "A0A8V0YTP2", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTP2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTP2" } ] } ] }, { "uniprot_ac": "A0A8V0YXZ5", "gene_name": "CDC42BPA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YXZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXZ5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YXZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXZ5" } ] } ] }, { "uniprot_ac": "A0A8V0YYX2", "gene_name": "PAK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YYX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYX2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YYX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYX2" } ] } ] }, { "uniprot_ac": "A0A8V0YYZ3", "gene_name": "SPEG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YYZ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYZ3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YYZ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYZ3" } ] } ] }, { "uniprot_ac": "A0A8V0YZ74", "gene_name": "MAP2K5", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZ74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZ74" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V0YZ74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZ74" } ] } ] }, { "uniprot_ac": "A0A8V0YZF2", "gene_name": "PAK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZF2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YZF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZF2" } ] } ] }, { "uniprot_ac": "A0A8V0YZK0", "gene_name": "MAP3K6", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZK0" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0YZK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZK0" } ] } ] }, { "uniprot_ac": "A0A8V0YZM1", "gene_name": "MOK", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZM1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0YZM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZM1" } ] }, { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZM1" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0YZM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZM1" } ] } ] }, { "uniprot_ac": "A0A8V0YZV9", "gene_name": "ATR", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZV9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YZV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZV9" } ] } ] }, { "uniprot_ac": "A0A8V0YZY4", "gene_name": "SBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZY4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YZY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZY4" } ] } ] }, { "uniprot_ac": "A0A8V0Z124", "gene_name": "VRK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z124", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z124" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z124", "database": 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"activity": "", "evidence": [ { "id": "A0A8V0Z283", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z283" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z283", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z283" } ] } ] }, { "uniprot_ac": "A0A8V0Z2E3", "gene_name": "PDIK1L", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z2E3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2E3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z2E3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2E3" } ] } ] }, { "uniprot_ac": "A0A8V0Z2Z3", "gene_name": "AAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z2Z3", "database": 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"ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z807", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z807" } ] } ] }, { "uniprot_ac": "A0A8V0Z8G2", "gene_name": "TTBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z8G2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8G2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z8G2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8G2" } ] } ] }, { "uniprot_ac": "A0A8V0Z8T4", "gene_name": "RPS6KC1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z8T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8T4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": 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O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZKA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKA2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZKA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKA2" } ] } ] }, { "uniprot_ac": "A0A8V0ZKM9", "gene_name": "STK36", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZKM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKM9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZKM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKM9" } ] } ] }, { "uniprot_ac": "A0A8V0ZLU3", "gene_name": "TLK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": 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"ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZPX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPX2" } ] } ] }, { "uniprot_ac": "A0A8V0ZQJ2", "gene_name": "RPS6KB2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZQJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQJ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZQJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQJ2" } ] } ] }, { "uniprot_ac": "A0A8V0ZQT5", "gene_name": "SLC13A3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZQT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQT5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": 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"database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSP4" } ] } ] }, { "uniprot_ac": "A0A8V0ZT63", "gene_name": "STK25", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZT63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT63" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZT63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT63" } ] } ] }, { "uniprot_ac": "A0A8V0ZUC6", "gene_name": "PAK6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZUC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUC6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZUC6", "database": "UniProtKB", "url": 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ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZYU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZYU6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZYU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZYU6" } ] } ] }, { "uniprot_ac": "A0A8V0ZZE4", "gene_name": "OBSCN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZZE4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZE4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZZE4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZE4" } ] } ] }, { "uniprot_ac": "A0A8V0ZZK5", "gene_name": "STK38", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZZK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZK5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZZK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZK5" } ] } ] }, { "uniprot_ac": "A0A8V0ZZV3", "gene_name": "MYO3B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZZV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZV3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZZV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZV3" } ] } ] }, { "uniprot_ac": "A0A8V1A069", "gene_name": "TESK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A069", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A069" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V1A069", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A069" } ] } ] }, { "uniprot_ac": "A0A8V1A0W4", "gene_name": "ULK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A0W4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0W4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A0W4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0W4" } ] } ] }, { "uniprot_ac": "A0A8V1A0Y8", "gene_name": "MAST2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A0Y8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0Y8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A0Y8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0Y8" } ] } ] }, { "uniprot_ac": "A0A8V1A1P3", "gene_name": "SRPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A1P3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1P3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A1P3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1P3" } ] } ] }, { "uniprot_ac": "A0A8V1A1Y7", "gene_name": "CDK2", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A1Y7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1Y7" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V1A1Y7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1Y7" } ] } ] }, { "uniprot_ac": "A0A8V1A2T9", "gene_name": "MAP3K14", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A2T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2T9" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V1A2T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2T9" } ] } ] }, { "uniprot_ac": "A0A8V1A3T8", "gene_name": "MAST3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A3T8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3T8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A3T8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3T8" } ] } ] }, { "uniprot_ac": "A0A8V1A4A1", "gene_name": "CAMKK2", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4A1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4A1" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V1A4A1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4A1" } ] } ] }, { "uniprot_ac": "A0A8V1A4J8", "gene_name": "MAPKAPK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4J8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4J8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A4J8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4J8" } ] } ] }, { "uniprot_ac": "A0A8V1A4Q4", "gene_name": "MAPK3", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4Q4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4Q4" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V1A4Q4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4Q4" } ] } ] }, { "uniprot_ac": "A0A8V1A4V7", "gene_name": "HIPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4V7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4V7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A4V7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4V7" } ] } ] }, { "uniprot_ac": "A0A8V1A513", "gene_name": "DAPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A513", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A513" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A513", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A513" } ] } ] }, { "uniprot_ac": "A0A8V1A675", "gene_name": "CSNK1G2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A675", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A675" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A675", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A675" } ] } ] }, { "uniprot_ac": "A0A8V1A7E0", "gene_name": "DYRK3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7E0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E0" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V1A7E0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E0" } ] } ] }, { "uniprot_ac": "A0A8V1A7E9", "gene_name": "SIK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7E9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A7E9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E9" } ] } ] }, { "uniprot_ac": "A0A8V1A7M0", "gene_name": "STK39", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7M0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7M0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A7M0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7M0" } ] } ] }, { "uniprot_ac": "A0A8V1A7P9", "gene_name": "DCAF1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A7P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P9" } ] } ] }, { "uniprot_ac": "A0A8V1A9S5", "gene_name": "NUAK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A9S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9S5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A9S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9S5" } ] } ] }, { "uniprot_ac": "A0A8V1ABF3", "gene_name": "PRKAA2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] } ] }, { "uniprot_ac": "A0A8V1ABP4", "gene_name": "DSTYK", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABP4" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V1ABP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABP4" } ] } ] }, { "uniprot_ac": "A0A8V1ABR8", "gene_name": "CAMK4L", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABR8" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V1ABR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABR8" } ] } ] }, { "uniprot_ac": "A0A8V1AC40", "gene_name": "CDK18", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AC40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC40" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V1AC40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC40" } ] } ] }, { "uniprot_ac": "A0A8V1ACB5", "gene_name": "MAPK13", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACB5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V1ACB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACB5" } ] } ] }, { "uniprot_ac": "A0A8V1ACF6", "gene_name": "PIM1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACF6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ACF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACF6" } ] } ] }, { "uniprot_ac": "A0A8V1ACK0", "gene_name": "MAPKAPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACK0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ACK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACK0" } ] } ] }, { "uniprot_ac": "A0A8V1ACW2", "gene_name": "WNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACW2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ACW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACW2" } ] } ] }, { "uniprot_ac": "A0A8V1ADF0", "gene_name": "MAP2K2", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ADF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADF0" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V1ADF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADF0" } ] } ] }, { "uniprot_ac": "A0A8V1ADN9", "gene_name": "NLK", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ADN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADN9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V1ADN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADN9" } ] } ] }, { "uniprot_ac": "A0A8V1ADT4", "gene_name": "MKNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ADT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADT4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ADT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADT4" } ] } ] }, { "uniprot_ac": "A0A8V1AE45", "gene_name": "ERN1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AE45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE45" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AE45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE45" } ] } ] }, { "uniprot_ac": "A0A8V1AEH4", "gene_name": "STK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AEH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEH4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AEH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEH4" } ] } ] }, { "uniprot_ac": "A0A8V1AFS4", "gene_name": "STKLD1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AFS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFS4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AFS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFS4" } ] } ] }, { "uniprot_ac": "A0A8V1AG70", "gene_name": "LOC100857512", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AG70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AG70" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AG70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AG70" } ] } ] }, { "uniprot_ac": "A0A8V1AH12", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AH12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH12" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AH12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH12" } ] } ] }, { "uniprot_ac": "A0A8V1AHA8", "gene_name": "NEK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AHA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHA8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AHA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHA8" } ] } ] }, { "uniprot_ac": "A0A8V1AIY7", "gene_name": "AATK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AIY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIY7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AIY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIY7" } ] } ] }, { "uniprot_ac": "A0A8V1AJA4", "gene_name": "RPS6KB1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AJA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJA4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AJA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJA4" } ] } ] }, { "uniprot_ac": "A0A8V1AKW4", "gene_name": "MAP2K4", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AKW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKW4" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V1AKW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKW4" } ] } ] }, { "uniprot_ac": "A0A8V1AM12", "gene_name": "GSG2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AM12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM12" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AM12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM12" } ] } ] }, { "uniprot_ac": "A0A8V1AMK5", "gene_name": "PRKCA", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AMK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMK5" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V1AMK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMK5" } ] } ] }, { "uniprot_ac": "A0A8V1AMQ2", "gene_name": "CAMKK1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AMQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMQ2" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V1AMQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMQ2" } ] } ] }, { "uniprot_ac": "A0A8V1AP60", "gene_name": "KSR1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AP60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP60" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AP60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP60" } ] } ] }, { "uniprot_ac": "E1BQN6", "gene_name": "PRKCZ", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BQN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQN6" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1BQN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQN6" } ] } ] }, { "uniprot_ac": "E1BQV7", "gene_name": "SLK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BQV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQV7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BQV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQV7" } ] } ] }, { "uniprot_ac": "E1BUG0", "gene_name": "CDK12", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] } ] }, { "uniprot_ac": "E1BW33", "gene_name": "SMG1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BW33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BW33" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BW33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BW33" } ] } ] }, { "uniprot_ac": "E1BWA3", "gene_name": "PRKCI", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BWA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWA3" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1BWA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWA3" } ] } ] }, { "uniprot_ac": "E1BWT0", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BWT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWT0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BWT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWT0" } ] } ] }, { "uniprot_ac": "E1BX69", "gene_name": "EIF2AK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BX69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BX69" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BX69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BX69" } ] } ] }, { "uniprot_ac": "E1BY69", "gene_name": "PIM3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BY69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BY69" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BY69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BY69" } ] } ] }, { "uniprot_ac": "E1BYH2", "gene_name": "TAOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BYH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BYH2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BYH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BYH2" } ] } ] }, { "uniprot_ac": "E1C093", "gene_name": "PIK3CG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.154", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.154", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] } ] }, { "uniprot_ac": "E1C2I2", "gene_name": "MASTL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C2I2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C2I2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C2I2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C2I2" } ] } ] }, { "uniprot_ac": "E1C581", "gene_name": "TBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C581", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C581" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C581", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C581" } ] } ] }, { "uniprot_ac": "E1C6T4", "gene_name": "PRKD3", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C6T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C6T4" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1C6T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C6T4" } ] } ] }, { "uniprot_ac": "E1C764", "gene_name": "BMP2K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C764", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C764" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C764", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C764" } ] } ] }, { "uniprot_ac": "E1C848", "gene_name": "MAP3K8", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C848", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C848" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1C848", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C848" } ] } ] }, { "uniprot_ac": "F1NA68", "gene_name": "CDK3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NA68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NA68" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1NA68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NA68" } ] } ] }, { "uniprot_ac": "F1NB57", "gene_name": "PLK2", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NB57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NB57" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "F1NB57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NB57" } ] } ] }, { "uniprot_ac": "F1NBT0", "gene_name": "STK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NBT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NBT0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1NBT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NBT0" } ] } ] }, { "uniprot_ac": "F1NCX7", "gene_name": "PLK1", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NCX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCX7" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "F1NCX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCX7" } ] } ] }, { "uniprot_ac": "F1NCY7", "gene_name": "MAPKAPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NCY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCY7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1NCY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCY7" } ] } ] }, { "uniprot_ac": "F1NJH1", "gene_name": "PRKCH", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NJH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NJH1" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1NJH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NJH1" } ] } ] }, { "uniprot_ac": "F1NKW3", "gene_name": "MAP3K15", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NKW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NKW3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1NKW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NKW3" } ] } ] }, { "uniprot_ac": "F1NLR7", "gene_name": "CLK3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NLR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NLR7" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "F1NLR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NLR7" } ] } ] }, { "uniprot_ac": "F1NUX4", "gene_name": "MTOR", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NUX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NUX4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1NUX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NUX4" } ] } ] }, { "uniprot_ac": "F1NVF2", "gene_name": "MAP2K6", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NVF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NVF2" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "F1NVF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NVF2" } ] } ] }, { "uniprot_ac": "F1P011", "gene_name": "CAMK2A", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1P011", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P011" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "F1P011", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P011" } ] } ] }, { "uniprot_ac": "F1P356", "gene_name": "NUAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1P356", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P356" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1P356", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P356" } ] } ] }, { "uniprot_ac": "F1P4G3", "gene_name": "HIPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1P4G3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P4G3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1P4G3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P4G3" } ] } ] }, { "uniprot_ac": "P05625", "gene_name": "RAF1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P05625", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05625" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P05625", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05625" } ] } ] }, { "uniprot_ac": "P10741", "gene_name": "MOS", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P10741", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P10741" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P10741", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P10741" } ] } ] }, { "uniprot_ac": "P13863", "gene_name": "CDK1", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P13863", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13863" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "P13863", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13863" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "P13863", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13863" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "P13863", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13863" } ] } ] }, { "uniprot_ac": "P18652", "gene_name": "RPS6KA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P18652", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P18652" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P18652", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P18652" } ] } ] }, { "uniprot_ac": "P21868", "gene_name": "CSNK2A1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P21868", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P21868" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P21868", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P21868" } ] } ] }, { "uniprot_ac": "P21869", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P21869", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P21869" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P21869", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P21869" } ] } ] }, { "uniprot_ac": "P53666", "gene_name": "LIMK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P53666", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P53666" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P53666", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P53666" } ] } ] }, { "uniprot_ac": "P67962", "gene_name": "CSNK1A1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P67962", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P67962" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P67962", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P67962" } ] } ] }, { "uniprot_ac": "P79996", "gene_name": "MAPK9", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P79996", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P79996" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "P79996", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P79996" } ] } ] }, { "uniprot_ac": "Q04982", "gene_name": "BRAF", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q04982", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q04982" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q04982", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q04982" } ] } ] }, { "uniprot_ac": "Q0GGW5", "gene_name": "STK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q0GGW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0GGW5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q0GGW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0GGW5" } ] } ] }, { "uniprot_ac": "Q5F3L1", "gene_name": "RPS6KA5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5F3L1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F3L1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q5F3L1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F3L1" } ] } ] }, { "uniprot_ac": "Q5F3W3", "gene_name": "MAPK6", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5F3W3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F3W3" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "Q5F3W3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F3W3" } ] } ] }, { "uniprot_ac": "Q5ZIU3", "gene_name": "DYRK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5ZIU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZIU3" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "Q5ZIU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZIU3" } ] } ] }, { "uniprot_ac": "Q5ZJH6", "gene_name": "ULK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5ZJH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJH6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q5ZJH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJH6" } ] } ] }, { "uniprot_ac": "Q5ZJK4", "gene_name": "STK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5ZJK4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJK4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q5ZJK4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJK4" } ] } ] }, { "uniprot_ac": "Q5ZJS0", "gene_name": "CSNK1G1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5ZJS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJS0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q5ZJS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJS0" } ] } ] }, { "uniprot_ac": "Q5ZKI0", "gene_name": "CAMK2D", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5ZKI0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKI0" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "Q5ZKI0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKI0" } ] } ] }, { "uniprot_ac": "Q5ZKN1", "gene_name": "CDK9", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5ZKN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKN1" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "Q5ZKN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKN1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q5ZKN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKN1" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "Q5ZKN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKN1" } ] } ] }, { "uniprot_ac": "Q5ZLL1", "gene_name": "CSNK1E", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5ZLL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZLL1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q5ZLL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZLL1" } ] } ] }, { "uniprot_ac": "Q6U1I9", "gene_name": "SGK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q6U1I9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6U1I9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q6U1I9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6U1I9" } ] } ] }, { "uniprot_ac": "Q6XUX0", "gene_name": "DSTYK", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q6XUX0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6XUX0" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "Q6XUX0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6XUX0" } ] } ] }, { "uniprot_ac": "Q7T0B1", "gene_name": "STK40", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q7T0B1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q7T0B1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q7T0B1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q7T0B1" } ] } ] }, { "uniprot_ac": "Q8AYC9", "gene_name": "CHEK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q8AYC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8AYC9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8AYC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8AYC9" } ] } ] }, { "uniprot_ac": "Q8QFP8", "gene_name": "LIMK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q8QFP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8QFP8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8QFP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8QFP8" } ] } ] }, { "uniprot_ac": "Q8QGX4", "gene_name": "PRKDC", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q8QGX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8QGX4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8QGX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8QGX4" } ] } ] }, { "uniprot_ac": "Q90771", "gene_name": "CDK6", 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"uniprotkb_annotation": "Protein kinase", "eco_id": "ECO_0000259", "start_pos": 131, "end_pos": 382, "start_aa": "Tyr", "end_aa": "Met", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.7.11.1", "ec_name": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "2.7.11.1", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1" }, { "id": "2.7.11.1", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.7.11.1" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 141, "end_pos": 143 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", 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{ "uniprot_canonical_ac": "A0A8V0YQD7-1", "uniprot_ac": "A0A8V0YQD7", "uniprot_id": "A0A8V0YQD7_CHICK", "mass": { "chemical_mass": 242586.0, "monoisotopic_mass": 242586.0 }, "refseq": { "ac": "XP_417693", "name": "AT-rich interactive domain-containing protein 1A isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_417693" }, "gene_names": [ { "name": "ARID1A", "type": "recommended", "evidence": [ { "id": "A0A8V0YQD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQD7" } ] }, { "name": "ARID1A", "type": "synonym", "evidence": [ { "id": "XP_417693", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_417693" } ] } ], "protein_names": [ { "name": "AT-rich interaction domain 1A", "type": "synonym", "evidence": [ { "id": "A0A8V0YQD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQD7/entry#names_and_taxonomy" } ] }, { "name": "AT-rich interactive domain-containing protein 1A isoform X1", "type": "synonym", "evidence": [ { "id": "XP_417693", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_417693" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052554.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jan 4, 2016 this sequence version replaced XP_417693.4. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_417693", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_417693" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQD7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQD7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ARID1A", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQD7", "locus": { "chromosome": "23", "start_pos": 406681, "end_pos": 464041, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010014301", "url": "https://www.ensembl.org/id/ENSGALG00010014301" } ] } } ], "crossref": [ { "id": "cd16876", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16876", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "419542", "url": "https://www.ncbi.nlm.nih.gov/gene/419542", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001606", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001606", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR021906", "url": "https://www.ebi.ac.uk/interpro/entry/IPR021906", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR030094", "url": "https://www.ebi.ac.uk/interpro/entry/IPR030094", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033388", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033388", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036431", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036431", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "CRPIDMD", "url": "https://omabrowser.org/oma/group/CRPIDMD/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YNI6", "url": "https://www.orthodb.org/?gene=A0A8V0YNI6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YNK6", "url": "https://www.orthodb.org/?gene=A0A8V0YNK6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YNL0", "url": "https://www.orthodb.org/?gene=A0A8V0YNL0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YQD7", "url": "https://www.orthodb.org/?gene=A0A8V0YQD7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YVE2", "url": "https://www.orthodb.org/?gene=A0A8V0YVE2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12656", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12656", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12656:SF12", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12656:SF12", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01388", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01388", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12031", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12031", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-3214858", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3214858", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-8939243", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8939243", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": 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"id": "A0A8V0YNK6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNK6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YNL0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNL0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YNL0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNL0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQD7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQD7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQD7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQD7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YVE2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YVE2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YVE2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YVE2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAQVVPAAASSLGAPAPAELKKAEAQQRDCPPEEAGGEAAAERGGEKQAESEGPPGKELQDAAESNGGGAGAESDLKSSNGNPGPRPAAAAATLNNNLPEPPGGGGISDGVGAPQQQQPPQQPPPSHPAALPPPAYGFGQPYGRGAQAAAAAAAAAAAAAAFHQHGGQQSPGMAALQSGGLEQSYPGPAGAPAGPPPPQNSHGGTEHGFPNHQYNSYYAAGAGRSAGSYPPPPQAYALSSPRGSAQSSAQAAAGAKSPAAAFQQQRFGVMGPSAAGGAGGGGATPQPTATPTLNQLLTSPSSARGYQGYPGGDYSGGPQDGGAAGKGPAAVDMVSQYGGGNSQGWAAAPGGAPPRSHHAPMSPGSSGGGGGGQSLGRSQQPSSPMDQMGKMRPQPYGGNNPYTQQQGPQAGPQQGHGYPGQPYGPQTPQRYPMGMQSRTQSTMGSISYAQQIPPYGQQGPNAYGQQSQTPYYNQQSPHPQQQQPPYSQQTPSQTPHSQPSYQQQQQPQSQAPQLQTSQPAYSQQQSQPPHQQSPTPYPQQQSTAQQHQQNQPPYSQQQSQSPYQQQQQTQQTASSALSQQSSSYPQSQPQQQQSAYSQQRFPPPQELSQESFGSQTSSAPSMASSKGQEDMNLNIQSRPSSLPDLSGSIDDLPMGTEGALSPGVSTSGISSSQGEQSNPAQSPFSPHTSPHLPGIRGPSPSPVGSPASVAQSRSGPLSPAAVPGNQMPPRPPSGQSDSIMHPSMNQSSIAQDRGYLQRNPQMPQYSSPQPGSALSPRQSSGGQMHAGMGPYQQNSMGSYGPQAGQYGPQGGYPRQPNYNALSNANYPSPGMGGSMNPMAAGSQMHGQSGVPPYSGLPPGRMSHAAMGNRPYGPNMANMPPQVGTGMCPPPGSMNRKAQEAAAAAMHAAANSIQNRPAGYPNMNQGGMMGTGPPYGQGINSMAGMINPQGPPYPMGGNMANNSAGMAASPEMMGLADVKLTPATKMNNKADGTPKAESKSKKSSSSTTTNEKITKLYELGGEPERKIWVDRYLAFTEEKAMGMTNLPAVGRKPLDLYRLYISVKEIGGLTQVNKNKKWRELATNLNVGTSSSAASSLKKQYIQCLYAFECKIERGEDPPPDIFAAADSKKSQTKIQPPSPAGSGSMQGPQTPQSTSSSMAEGGDLKPPTPASTPHSQMPPLPGIRSNSVGLQDAFTDGSDPTFQKRNSMTPNPGYQPSMNTSDMMGRMSYEPNKDPYSSMRKAPGSDPFMSSGQGPNSGMGDPYNRAAGPGMGNMAMGQRPHYPYGGPYDRVRTEPGMGPEGNLAAGTPQPNIMPSTSESGMYSPSRYPQQQQQQQRHDSYGNQFSTQGTSSGSPFPSQQTTMYQQQQQNYKRPMDGSYGPPAKRHEGEMYNVPYSAGQGQTQQQLPPAQTQQPSQQQAAQPSPQQDLYNQYGSTYPAADRRSAGGPQNQFPFQFGRDRVSAPPGSNAQQNMPPQMMGGPIQSAPEGPQQGAMWQGRNEIGYSYPNRQSTGSAPQGPAYHGVTRTDDILHSEQRVNHEGPWPSHGNRQPPYGPSAPVPPMTRPPQSNYQTPPSMQNHIPQVSSPAPLPRPLENRTSPSKSPFLHSGMKMQKAGPPVPASHITPAAVQPPMIRRDITFPPGSVEATQPVLKQRRRLTAKDIGTPEAWRVMMSLKSGLLAESTWALDTINILLYDDNSIMTFNLSQLPGLLELLVEYFRRCLIEIFGILKEYEVGDPGQRTLLDPQRFCRSSASSHEEGEEDEELRSLNNEEEEDDEEEEEAAFSSKDKAPLECSEEKLVSKFDKLPIKIVQKNDPFVVDYSDKLGRVQEFESGLLHWRIGGGDTTEHIQTHFESKMELPMIHKRASCNSVSRKRAAAESNPSTREGEALPSDSSSEKRITATMDDMLSARPSSLSGEEEEAKASETEKESKFPFGISPAQSHRNIKILEDEPHSKDETPLCTIQDWQDSLAKRCICVSNIIRSLSFVPGNDFEMSKHPGLLLILGKLILLHHKHPERKQAPLTYEKEEEQDQGVSCNKVEWWWDCLEVLRENTLVTLANISGQLDLSPYPESICLPILDGLLHWAVCPSAEAQDPFPTLGPNAVLSPQRLVLETLSKLSIQDNNVDLILATPPFSRLEKLYSTLVRFLSDRKNPVCREMAVVLLANLAQGDSLAARAIAVQKGSIGNLLGFLEDSLAATQFQQSQAGLMHMQNAPFESTSVDMMRRAARALLALAKVDENHSEFTLYESRLLDISVSPLMNSLVSQVICDVLFLIGQS", "length": 2277, "header": "tr|A0A8V0YQD7-1|A0A8V0YQD7_CHICK Isoform 1 of AT-rich interaction domain 1A OS=Gallus gallus OX=9031 GN=ARID1A PE=1 SV=1 CANONICAL=A0A8V0YQD7-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YNI6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQD7/entry#A0A8V0YNI6-1", "sequence": { "sequence": "MAALQSGGLEQSYPGPAGAPAGPPPPQNSHGGTEHGFPNHQYNSYYAAGAGRSAGSYPPPPQAYALSSPRGSAQSSAQAAAGAKSPAAAFQQQRFGVMGPSAAGGAGGGGATPQPTATPTLNQLLTSPSSARGYQGYPGGDYSGGPQDGGAAGKGPAAVDMVSQYGGGNSQGWAAAPGGAPPRSHHAPMSPGSSGGGGGGQSLGRSQQPSSPMDQMGKMRPQPYGGNNPYTQQQGPQAGPQQGHGYPGQPYGPQTPQRYPMGMQSRTQSTMGSISYAQQAAWETTPGSRRDRCMRICGILPSTRGSSRAIPPYGQQGPNAYGQQSQTPYYNQQSPHPQQQQPPYSQQTPSQTPHSQPSYQQQQQPQSQAPQLQTSQPAYSQQQSQPPHQQSPTPYPQQQSTAQQHQQNQPPYSQQQSQSPYQQQQQTQQTASSALSQQSSSYPQSQPQQQQSAYSQQRFPPPQELSQESFGSQTSSAPSMASSKGQEDMNLNIQSRPSSLPDLSGSIDDLPMGTEGALSPGVSTSGISSSQGEQSNPAQSPFSPHTSPHLPGIRGPSPSPVGSPASVAQSRSGPLSPAAVPGNQMPPRPPSGQSDSIMHPSMNQSSIAQDRGYLQRNPQMPQYSSPQPGSALSPRQSSGGQMHAGMGPYQQNSMGSYGPQAGQYGPQGGYPRQPNYNALSNANYPSPGMGGSMNPMAAGSQMHGQSGVPPYSGLPPGRMSHAAMGNRPYGPNMANMPPQVGTGMCPPPGSMNRKAQEAAAAAMHAAANSIQNRPAGYPNMNQGGMMGTGPPYGQGINSMAGMINPQGPPYPMGGNMANNSAGMAASPEMMGLADVKLTPATKMNNKADGTPKAESKSKKSSSSTTTNEKITKLYELGGEPERKIWVDRYLAFTEEKAMGMTNLPAVGRKPLDLYRLYISVKEIGGLTQVNKNKKWRELATNLNVGTSSSAASSLKKQYIQCLYAFECKIERGEDPPPDIFAAADSKKSQTKIQPPSPAGSGSMQGPQTPQSTSSSMAEGGDLKPPTPASTPHSQMPPLPGIRSNSVGLQDAFTDGSDPTFQKRNSMTPNPGYQPSMNTSDMMGRMSYEPNKDPYSSMRKAPGSDPFMSSGQGPNSGMGDPYNRAAGPGMGNMAMGQRPHYPYGGPYDRVRTEPGMGPEGNLAAGTPQPNIMPSTSESGMYSPSRYPQQQQQQQRHDSYGNQFSTQGTSSGSPFPSQQTTMYQQQQQNYKRPMDGSYGPPAKRHEGEMYNVPYSAGQGQTQQQLPPAQTQQPSQQQAAQPSPQQDLYNQYGSTYPAADRRSAGGPQNQFPFQFGRDRVSAPPGSNAQQNMPPQMMGGPIQSAPEGPQQGAMWQGRNEIGYSYPNRQSTGSAPQGPAYHGVTRTDDILHSEQRVNHEGPWPSHGNRQPPYGPSAPVPPMTRPPQSNYQTPPSMQNHIPQVSSPAPLPRPLENRTSPSKSPFLHSGMKMQKAGPPVPASHITPAAVQPPMIRRDITFPPGSVEATQPVLKQRRRLTAKDIGTPEAWRVMMSLKSGLLAESTWALDTINILLYDDNSIMTFNLSQLPGLLELLVEYFRRCLIEIFGILKEYEVGDPGQRTLLDPQRFCRSSASSHEEGEEDEELRSLNNEEEEDDEEEEEAAFSSKDKAPLECSEEKLVSKFDKLPIKIVQKNDPFVVDYSDKLGRVQEFESGLLHWRIGGGDTTEHIQTHFESKMELPMIHKRASCNSVSRKRAAAESNPSTREGEALPSDSSSEKRITATMDDMLSARPSSLSGEEEEAKASETEKESKFPFGISPAQSHRNIKILEDEPHSKDETPLCTIQDWQDSLAKRCICVSNIIRSLSFVPGNDFEMSKHPGLLLILGKLILLHHKHPERKQAPLTYEKEEEQDQGVSCNKVEWWWDCLEVLRENTLVTLANISGQLDLSPYPESICLPILDGLLHWAVCPSAEAQDPFPTLGPNAVLSPQRLVLETLSKLSIQDNNVDLILATPPFSRLEKLYSTLVRFLSDRKNPVCREMAVVLLANLAQGDSLAARAIAVQKGSIGNLLGFLEDSLAATQFQQSQAGLMHMQNAPFESTSVDMMRRAARALLALAKVDENHSEFTLYESRLLDISVSPLMNSLVSQVICDVLFLIGQS", "length": 2134, "header": "tr|A0A8V0YNI6-1|A0A8V0YQD7_CHICK Computationally mapped isoform of AT-rich interaction domain 1A OS=Gallus gallus OX=9031 GN=ARID1A PE=1 SV=1 CANONICAL=A0A8V0YQD7-1" }, "locus": { "chromosome": "23", "start_pos": 462001, "end_pos": 407210, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034441.1", "url": "https://www.ensembl.org/id/ENSGALT00010034441.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020229.1", "url": "https://www.ensembl.org/id/ENSGALP00010020229.1" } ] } }, { "isoform_ac": "A0A8V0YNK6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQD7/entry#A0A8V0YNK6-1", "sequence": { "sequence": "MRPLRFPPKVGCGSCASAAPGGAPGSSARGYQGYPGGDYSGGPQDGGAAGKGPAAVDMVSQYGGGNSQGWAAAPGGAPPRSHHAPMSPGSSGGGGGGQSLGRSQQPSSPMDQMGKMRPQPYGGNNPYTQQQGPQAGPQQGHGYPGQPYGPQTPQRYPMGMQSRTQSTMGSISYAQQIPPYGQQGPNAYGQQSQTPYYNQQSPHPQQQQPPYSQQTPSQTPHSQPSYQQQQQPQSQAPQLQTSQPAYSQQQSQPPHQQSPTPYPQQQSTAQQHQQNQPPYSQQQSQSPYQQQQQTQQTASSALSQQSSSYPQSQPQQQQSAYSQQRFPPPQELSQESFGSQTSSAPSMASSKGQEDMNLNIQSRPSSLPDLSGSIDDLPMGTEGALSPGVSTSGISSSQGEQSNPAQSPFSPHTSPHLPGIRGPSPSPVGSPASVAQSRSGPLSPAAVPGNQMPPRPPSGQSDSIMHPSMNQSSIAQDRGYLQRNPQMPQYSSPQPGSALSPRQSSGGQMHAGMGPYQQNSMGSYGPQAGQYGPQGGYPRQPNYNALSNANYPSPGMGGSMNPMAAGSQMHGQSGVPPYSGLPPGRMSHAAMGNRPYGPNMANMPPQVGTGMCPPPGSMNRKAQEAAAAAMHAAANSIQNRPAGYPNMNQGGMMGTGPPYGQGINSMAGMINPQGPPYPMGGNMANNSAGMAASPEMMGLADVKLTPATKMNNKADGTPKAESKSKKSSSSTTTNEKITKLYELGGEPERKIWVDRYLAFTEEKAMGMTNLPAVGRKPLDLYRLYISVKEIGGLTQVNKNKKWRELATNLNVGTSSSAASSLKKQYIQCLYAFECKIERGEDPPPDIFAAADSKKSQTKIQPPSPAGSGSMQGPQTPQSTSSSMAEGGDLKPPTPASTPHSQMPPLPGIRSNSVGLQDAFTDGSDPTFQKRNSMTPNPGYQPSMNTSDMMGRMSYEPNKDPYSSMRKAPGSDPFMSSGQGPNSGMGDPYNRAAGPGMGNMAMGQRPHYPYGGPYDRVRTEPGMGPEGNLAAGTPQPNIMPSTSESGMYSPSRYPQQQQQQQRHDSYGNQFSTQGTSSGSPFPSQQTTMYQQQQQNYKRPMDGSYGPPAKRHEGEMYNVPYSAGQGQTQQQLPPAQTQQPSQQQAAQPSPQQDLYNQYGSTYPAADRRSAGGPQNQFPFQFGRDRVSAPPGSNAQQNMPPQMMGGPIQSAPEGPQQGAMWQGRNEIGYSYPNRQSTGSAPQGPAYHGVTRTDDILHSEQRVNHEGPWPSHGNRQPPYGPSAPVPPMTRPPQSNYQTPPSMQNHIPQVSSPAPLPRPLENRTSPSKSPFLHSGMKMQKAGPPVPASHITPAAVQPPMIRRDITFPPGSVEATQPVLKQRRRLTAKDIGTPEAWRVMMSLKSGLLAESTWALDTINILLYDDNSIMTFNLSQLPGLLELLVEYFRRCLIEIFGILKEYEVGDPGQRTLLDPQRFCRSSASSHEEGEEDEELRSLNNEEEEDDEEEEEAAFSSKDKAPLECSEEKLVSKFDKLPIKIVQKNDPFVVDYSDKLGRVQEFESGLLHWRIGGGDTTEHIQTHFESKMELPMIHKRASCNSVSRKRAAAESNPSTREGEALPSDSSSEKRITATMDDMLSARPSSLSGEEEEAKASETEKESKFPFGISPAQSHRNIKILEDEPHSKDETPLCTIQDWQDSLAKRCICVSNIIRSLSFVPGNDFEMSKHPGLLLILGKLILLHHKHPERKQAPLTYEKEEEQDQGVSCNKVEWWWDCLEVLRENTLVTLANISGQLDLSPYPESICLPILDGLLHWAVCPSAEAQDPFPTLGPNAVLSPQRLVLETLSKLSIQDNNVDLILATPPFSRLEKLYSTLVRFLSDRKNPVCREMAVVLLANLAQGDSLAARAIAVQKGSIGNLLGFLEDSLAATQFQQSQAGLMHMQNAPFESTSVDMMRRAARALLALAKVDENHSEFTLYESRLLDISVSPLMNSLVSQVICDVLFLIGQS", "length": 2001, "header": "tr|A0A8V0YNK6-1|A0A8V0YNK6_CHICK Computationally mapped isoform of AT-rich interaction domain 1A OS=Gallus gallus OX=9031 GN=ARID1A PE=1 SV=1 CANONICAL=A0A8V0YQD7-1" }, "locus": { "chromosome": "23", "start_pos": 463415, "end_pos": 407210, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034463.1", "url": "https://www.ensembl.org/id/ENSGALT00010034463.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020244.1", "url": "https://www.ensembl.org/id/ENSGALP00010020244.1" } ] } }, { "isoform_ac": "A0A8V0YNL0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQD7/entry#A0A8V0YNL0-1", "sequence": { "sequence": "MIIVWPSSPMDQMGKMRPQPYGGNNPYTQQQGPQAGPQQGHGYPGQPYGPQTPQRYPMGMQSRTQSTMGSISYAQQIPPYGQQGPNAYGQQSQTPYYNQQSPHPQQQQPPYSQQTPSQTPHSQPSYQQQQQPQSQAPQLQTSQPAYSQQQSQPPHQQSPTPYPQQQSTAQQHQQNQPPYSQQQSQSPYQQQQQTQQTASSALSQQSSSYPQSQPQQQQSAYSQQRFPPPQELSQESFGSQTSSAPSMASSKGQEDMNLNIQSRPSSLPDLSGSIDDLPMGTEGALSPGVSTSGISSSQGEQSNPAQSPFSPHTSPHLPGIRGPSPSPVGSPASVAQSRSGPLSPAAVPGNQMPPRPPSGQSDSIMHPSMNQSSIAQDRGYLQRNPQMPQYSSPQPGSALSPRQSSGGQMHAGMGPYQQNSMGSYGPQAGQYGPQGGYPRQPNYNALSNANYPSPGMGGSMNPMAAGSQMHGQSGVPPYSGLPPGRMSHAAMGNRPYGPNMANMPPQVGTGMCPPPGSMNRKAQEAAAAAMHAAANSIQNRPAGYPNMNQGGMMGTGPPYGQGINSMAGMINPQGPPYPMGGNMANNSAGMAASPEMMGLADVKLTPATKMNNKADGTPKAESKSKKSSSSTTTNEKITKLYELGGEPERKIWVDRYLAFTEEKAMGMTNLPAVGRKPLDLYRLYISVKEIGGLTQVNKNKKWRELATNLNVGTSSSAASSLKKQYIQCLYAFECKIERGEDPPPDIFAAADSKKSQTKIQPPSPAGSGSMQGPQTPQSTSSSMAEGGDLKPPTPASTPHSQMPPLPGIRSNSVGLQDAFTDGSDPTFQKRNSMTPNPGYQPSMNTSDMMGRMSYEPNKDPYSSMRKAPGSDPFMSSGQGPNSGMGDPYNRAAGPGMGNMAMGQRPHYPYGGPYDRVRTEPGMGPEGNLAAGTPQPNIMPSTSESGMYSPSRYPQQQQQQQRHDSYGNQFSTQGTSSGSPFPSQQTTMYQQQQQNYKRPMDGSYGPPAKRHEGEMYNVPYSAGQGQTQQQLPPAQTQQPSQQQAAQPSPQQDLYNQYGSTYPAADRRSAGGPQNQFPFQFGRDRVSAPPGSNAQQNMPPQMMGGPIQSAPEGPQQGAMWQGRNEIGYSYPNRQSTGSAPQGPAYHGVTRTDDILHSEQRVNHEGPWPSHGNRQPPYGPSAPVPPMTRPPQSNYQTPPSMQNHIPQVSSPAPLPRPLENRTSPSKSPFLHSGMKMQKAGPPVPASHITPAAVQPPMIRRDITFPPGSVEATQPVLKQRRRLTAKDIGTPEAWRVMMSLKSGLLAESTWALDTINILLYDDNSIMTFNLSQLPGLLELLVEYFRRCLIEIFGILKEYEVGDPGQRTLLDPQRFCRSSASSHEEGEEDEELRSLNNEEEEDDEEEEEAAFSSKDKAPLECSEEKLVSKFDKLPIKIVQKNDPFVVDYSDKLGRVQEFESGLLHWRIGGGDTTEHIQTHFESKMELPMIHKRASCNSVSRKRAAAESNPSTREGEALPSDSSSEKRITATMDDMLSARPSSLSGEEEEAKASETEKESKFPFGISPAQSHRNIKILEDEPHSKDETPLCTIQDWQDSLAKRCICVSNIIRSLSFVPGNDFEMSKHPGLLLILGKLILLHHKHPERKQAPLTYEKEEEQDQGVSCNKVEWWWDCLEVLRENTLVTLANISGQLDLSPYPESICLPILDGLLHWAVCPSAEAQDPFPTLGPNAVLSPQRLVLETLSKLSIQDNNVDLILATPPFSRLEKLYSTLVRFLSDRKNPVCREMAVVLLANLAQGDSLAARAIAVQKGSIGNLLGFLEDSLAATQFQQSQAGLMHMQNAPFESTSVDMMRRAARALLALAKVDENHSEFTLYESRLLDISVSPLMNSLVSQVICDVLFLIGQS", "length": 1901, "header": "tr|A0A8V0YNL0-1|A0A8V0YNL0_CHICK Computationally mapped isoform of AT-rich interaction domain 1A OS=Gallus gallus OX=9031 GN=ARID1A PE=1 SV=1 CANONICAL=A0A8V0YQD7-1" }, "locus": { "chromosome": "23", "start_pos": 459818, "end_pos": 407210, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034431.1", "url": "https://www.ensembl.org/id/ENSGALT00010034431.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020222.1", "url": "https://www.ensembl.org/id/ENSGALP00010020222.1" } ] } }, { "isoform_ac": "A0A8V0YQD7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQD7/entry#A0A8V0YQD7-1", "sequence": { "sequence": "MAAQVVPAAASSLGAPAPAELKKAEAQQRDCPPEEAGGEAAAERGGEKQAESEGPPGKELQDAAESNGGGAGAESDLKSSNGNPGPRPAAAAATLNNNLPEPPGGGGISDGVGAPQQQQPPQQPPPSHPAALPPPAYGFGQPYGRGAQAAAAAAAAAAAAAAFHQHGGQQSPGMAALQSGGLEQSYPGPAGAPAGPPPPQNSHGGTEHGFPNHQYNSYYAAGAGRSAGSYPPPPQAYALSSPRGSAQSSAQAAAGAKSPAAAFQQQRFGVMGPSAAGGAGGGGATPQPTATPTLNQLLTSPSSARGYQGYPGGDYSGGPQDGGAAGKGPAAVDMVSQYGGGNSQGWAAAPGGAPPRSHHAPMSPGSSGGGGGGQSLGRSQQPSSPMDQMGKMRPQPYGGNNPYTQQQGPQAGPQQGHGYPGQPYGPQTPQRYPMGMQSRTQSTMGSISYAQQIPPYGQQGPNAYGQQSQTPYYNQQSPHPQQQQPPYSQQTPSQTPHSQPSYQQQQQPQSQAPQLQTSQPAYSQQQSQPPHQQSPTPYPQQQSTAQQHQQNQPPYSQQQSQSPYQQQQQTQQTASSALSQQSSSYPQSQPQQQQSAYSQQRFPPPQELSQESFGSQTSSAPSMASSKGQEDMNLNIQSRPSSLPDLSGSIDDLPMGTEGALSPGVSTSGISSSQGEQSNPAQSPFSPHTSPHLPGIRGPSPSPVGSPASVAQSRSGPLSPAAVPGNQMPPRPPSGQSDSIMHPSMNQSSIAQDRGYLQRNPQMPQYSSPQPGSALSPRQSSGGQMHAGMGPYQQNSMGSYGPQAGQYGPQGGYPRQPNYNALSNANYPSPGMGGSMNPMAAGSQMHGQSGVPPYSGLPPGRMSHAAMGNRPYGPNMANMPPQVGTGMCPPPGSMNRKAQEAAAAAMHAAANSIQNRPAGYPNMNQGGMMGTGPPYGQGINSMAGMINPQGPPYPMGGNMANNSAGMAASPEMMGLADVKLTPATKMNNKADGTPKAESKSKKSSSSTTTNEKITKLYELGGEPERKIWVDRYLAFTEEKAMGMTNLPAVGRKPLDLYRLYISVKEIGGLTQVNKNKKWRELATNLNVGTSSSAASSLKKQYIQCLYAFECKIERGEDPPPDIFAAADSKKSQTKIQPPSPAGSGSMQGPQTPQSTSSSMAEGGDLKPPTPASTPHSQMPPLPGIRSNSVGLQDAFTDGSDPTFQKRNSMTPNPGYQPSMNTSDMMGRMSYEPNKDPYSSMRKAPGSDPFMSSGQGPNSGMGDPYNRAAGPGMGNMAMGQRPHYPYGGPYDRVRTEPGMGPEGNLAAGTPQPNIMPSTSESGMYSPSRYPQQQQQQQRHDSYGNQFSTQGTSSGSPFPSQQTTMYQQQQQNYKRPMDGSYGPPAKRHEGEMYNVPYSAGQGQTQQQLPPAQTQQPSQQQAAQPSPQQDLYNQYGSTYPAADRRSAGGPQNQFPFQFGRDRVSAPPGSNAQQNMPPQMMGGPIQSAPEGPQQGAMWQGRNEIGYSYPNRQSTGSAPQGPAYHGVTRTDDILHSEQRVNHEGPWPSHGNRQPPYGPSAPVPPMTRPPQSNYQTPPSMQNHIPQVSSPAPLPRPLENRTSPSKSPFLHSGMKMQKAGPPVPASHITPAAVQPPMIRRDITFPPGSVEATQPVLKQRRRLTAKDIGTPEAWRVMMSLKSGLLAESTWALDTINILLYDDNSIMTFNLSQLPGLLELLVEYFRRCLIEIFGILKEYEVGDPGQRTLLDPQRFCRSSASSHEEGEEDEELRSLNNEEEEDDEEEEEAAFSSKDKAPLECSEEKLVSKFDKLPIKIVQKNDPFVVDYSDKLGRVQEFESGLLHWRIGGGDTTEHIQTHFESKMELPMIHKRASCNSVSRKRAAAESNPSTREGEALPSDSSSEKRITATMDDMLSARPSSLSGEEEEAKASETEKESKFPFGISPAQSHRNIKILEDEPHSKDETPLCTIQDWQDSLAKRCICVSNIIRSLSFVPGNDFEMSKHPGLLLILGKLILLHHKHPERKQAPLTYEKEEEQDQGVSCNKVEWWWDCLEVLRENTLVTLANISGQLDLSPYPESICLPILDGLLHWAVCPSAEAQDPFPTLGPNAVLSPQRLVLETLSKLSIQDNNVDLILATPPFSRLEKLYSTLVRFLSDRKNPVCREMAVVLLANLAQGDSLAARAIAVQKGSIGNLLGFLEDSLAATQFQQSQAGLMHMQNAPFESTSVDMMRRAARALLALAKVDENHSEFTLYESRLLDISVSPLMNSLVSQVICDVLFLIGQS", "length": 2277, "header": "tr|A0A8V0YQD7-1|A0A8V0YQD7_CHICK Isoform 1 of AT-rich interaction domain 1A OS=Gallus gallus OX=9031 GN=ARID1A PE=1 SV=1 CANONICAL=A0A8V0YQD7-1" }, "locus": { "chromosome": "23", "start_pos": 462520, "end_pos": 407210, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034454.1", "url": "https://www.ensembl.org/id/ENSGALT00010034454.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020238.1", "url": "https://www.ensembl.org/id/ENSGALP00010020238.1" } ] } }, { "isoform_ac": "A0A8V0YVE2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQD7/entry#A0A8V0YVE2-1", "sequence": { "sequence": "MHSNRCITPLLPLLTVGLYLMLCPEWWLQRCECTEEQEPSSPMDQMGKMRPQPYGGNNPYTQQQGPQAGPQQGHGYPGQPYGPQTPQRYPMGMQSRTQSTMGSISYAQQIPPYGQQGPNAYGQQSQTPYYNQQSPHPQQQQPPYSQQTPSQTPHSQPSYQQQQQPQSQAPQLQTSQPAYSQQQSQPPHQQSPTPYPQQQSTAQQHQQNQPPYSQQQSQSPYQQQQQTQQTASSALSQQSSSYPQSQPQQQQSAYSQQRFPPPQELSQESFGSQTSSAPSMASSKGQEDMNLNIQSRPSSLPDLSGSIDDLPMGTEGALSPGVSTSGISSSQGEQSNPAQSPFSPHTSPHLPGIRGPSPSPVGSPASVAQSRSGPLSPAAVPGNQMPPRPPSGQSDSIMHPSMNQSSIAQDRGYLQRNPQMPQYSSPQPGSALSPRQSSGGQMHAGMGPYQQNSMGSYGPQAGQYGPQGGYPRQPNYNALSNANYPSPGMGGSMNPMAAGSQMHGQSGVPPYSGLPPGRMSHAAMGNRPYGPNMANMPPQVGTGMCPPPGSMNRKAQEAAAAAMHAAANSIQNRPAGYPNMNQGGMMGTGPPYGQGINSMAGMINPQGPPYPMGGNMANNSAGMAASPEMMGLADVKLTPATKMNNKADGTPKAESKSKKSSSSTTTNEKITKLYELGGEPERKIWVDRYLAFTEEKAMGMTNLPAVGRKPLDLYRLYISVKEIGGLTQVNKNKKWRELATNLNVGTSSSAASSLKKQYIQCLYAFECKIERGEDPPPDIFAAADSKKSQTKIQPPSPAGSGSMQGPQTPQSTSSSMAEGGDLKPPTPASTPHSQMPPLPGIRSNSVGLQDAFTDGSDPTFQKRNSMTPNPGYQPSMNTSDMMGRMSYEPNKDPYSSMRKAPGSDPFMSSGQGPNSGMGDPYNRAAGPGMGNMAMGQRPHYPYGGPYDRVRTEPGMGPEGNLAAGTPQPNIMPSTSESGMYSPSRYPQQQQQQQRHDSYGNQFSTQGTSSGSPFPSQQTTMYQQQQQNYKRPMDGSYGPPAKRHEGEMYNVPYSAGQGQTQQQLPPAQTQQPSQQQAAQPSPQQDLYNQYGSTYPAADRRSAGGPQNQFPFQFGRDRVSAPPGSNAQQNMPPQMMGGPIQSAPEGPQQGAMWQGRNEIGYSYPNRQSTGSAPQGPAYHGVTRTDDILHSEQRVNHEGPWPSHGNRQPPYGPSAPVPPMTRPPQSNYQTPPSMQNHIPQVSSPAPLPRPLENRTSPSKSPFLHSGMKMQKAGPPVPASHITPAAVQPPMIRRDITFPPGSVEATQPVLKQRRRLTAKDIGTPEAWRVMMSLKSGLLAESTWALDTINILLYDDNSIMTFNLSQLPGLLELLVEYFRRCLIEIFGILKEYEVGDPGQRTLLDPQRFCRSSASSHEEGEEDEELRSLNNEEEEDDEEEEEAAFSSKDKAPLECSEEKLVSKFDKLPIKIVQKNDPFVVDYSDKLGRVQEFESGLLHWRIGGGDTTEHIQTHFESKMELPMIHKRASCNSVSRKRAAAESNPSTREGEALPSDSSSEKRITATMDDMLSARPSSLSGEEEEAKASETEKESKFPFGISPAQSHRNIKILEDEPHSKDETPLCTIQDWQDSLAKRCICVSNIIRSLSFVPGNDFEMSKHPGLLLILGKLILLHHKHPERKQAPLTYEKEEEQDQGVSCNKVEWWWDCLEVLRENTLVTLANISGQLDLSPYPESICLPILDGLLHWAVCPSAEAQDPFPTLGPNAVLSPQRLVLETLSKLSIQDNNVDLILATPPFSRLEKLYSTLVRFLSDRKNPVCREMAVVLLANLAQGDSLAARAIAVQKGSIGNLLGFLEDSLAATQFQQSQAGLMHMQNAPFESTSVDMMRRAARALLALAKVDENHSEFTLYESRLLDISVSPLMNSLVSQVICDVLFLIGQS", "length": 1934, "header": "tr|A0A8V0YVE2-1|A0A8V0YVE2_CHICK Computationally mapped isoform of AT-rich interaction domain 1A OS=Gallus gallus OX=9031 GN=ARID1A PE=1 SV=1 CANONICAL=A0A8V0YQD7-1" }, "locus": { "chromosome": "23", "start_pos": 453783, "end_pos": 407210, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034425.1", "url": "https://www.ensembl.org/id/ENSGALT00010034425.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020216.1", "url": "https://www.ensembl.org/id/ENSGALP00010020216.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-3214858", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3214858", "resource": "Reactome", "description": "RMTs methylate histone arginines" }, { "id": "R-GGA-8939243", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8939243", "resource": "Reactome", "description": "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" }, { "id": "R-GGA-9933937", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9933937", "resource": "Reactome", "description": "Formation of the canonical BAF (cBAF) complex" }, { "id": "R-GGA-9933946", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9933946", "resource": "Reactome", "description": "Formation of the embryonic stem cell BAF (esBAF) complex" }, { "id": "R-GGA-9934037", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9934037", "resource": "Reactome", "description": "Formation of neuronal progenitor and neuronal BAF (npBAF and nBAF)" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3Q1M2B9-1", "protein_name": "AT-rich interaction domain 1A", "gene_name": "ARID1A", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAAQVAPAAASSLGNPPPPPPSELKKAEQQQQQQREEAGGEAAAAVAAERGEMKAAAGQESEGPAVGPPQPLGKELQDGAESNGGGGGGGAGGPGAEPDLKNSNGNAGPRPALNNNLTEPPGGGGGGSSDGVGAPPHSAAAALPPPAYGFGQPYGRSPSAVAAAAAAVFHQQHGGQQSPGLAALQSGGGGGGLEPYAGPQQNSHDHGFPNHQYNSYYPNRSAYPPPPQAYALSSPRGGTPGSGAAAAAAGSKPPPSSSASASSSSSSFAQQRFGAMGGGGPSAAAGGTPQPTATPTLNQLLTSPSSARGYQGYPGGDYGGGPQDGGAGKGPADMASQCWGAAAAAAAAAAAASGGAQQRSHHAPMSPGSSGGGGQPLVRTPQPSSPMDQMGKMRPQPYGGTNPYSQQQGPPSGPQQGHGYPGQPYGSQTPQRYPMTMQGRAQSTMGGLSYAQQIPPYGQQGPSGYGQQGQTPYYNQQSPHPQQQQPPYSQQPPSQTPHAQPSYQQQPQSQPPQLQSSQPPYSQQPSQPPHQPSPTPYPSQQSSTQQHPQSQPPYSQPQAQSPYQQQQPQQPASSTLSQQAAYPQPQSQQSQQTAYSQQRFPPPQELSQDSFGSQASSAPSMTSSKGGQEDMNLSLQSRPSSLPDLSGSIDDLPMGTEGALSPGVSTSGISSSQGEQSNPAQSPFSPHTSPHLPGIRGPSPSPVGSPASVAQSRSGPLSPAAVPGNQMPPRPPSGQSDSIMHPSMNQSSIAQDRGYMQRNPQMPQYSSPQPGSALSPRQPSGGQMHTGMGSYQQNSMGSYGPQGSQYGPQGGYPRQPNYNALPNANYPSAGMAGSMNPMGAGGQMHGQPGIPPYGTLPPGRMSHASMGNRPYGPNMANMPPQVGSGMCPPPGGMNRKTQETAVAMHVAANSIQNRPPGYPNMNQGGIMGTGPPYGQGINSMAGMINPQGPPYPMGGTMANNSAGMAASPEMMGLGDVKLTPASKMNNKADGTPKTESKSKKSSSSTTTNEKITKLYELGGEPERKMWVDRYLAFTEEKAMGMTNLPAVGRKPLDLYRLYVSVKEIGGLTQVNKNKKWRELATNLNVGTSSSAASSLKKQYIQCLYAFECKIERGEDPPPDIFAAADSKKSQPKIQPPSPAGSGSMQGPQTPQSTSSSMAEGGDLKPPTPASTPHSQIPPLPGMSRSNSVGIQDAFPDGSDPTFQKRNSMTPNPGYQPSMNTSDMMGRMSYEPNKDPYGSMRKAPGSDPFMSSGQGPNGGMGDPYSRAAGPGLGNVAMGPRQHYPYGGPYDRVRTEPGIGPEGNMGTGAPQPNLMPSNPDSGMYSPSRYPPQQQQQQQRHDSYGNQFSAQGTPSGSPFPSQQTTMYQQQQQNYKRPMDGTYGPPAKRHEGEMYSVPYSAGQGQPQQQQLPPAQPPPANQQQAAQPPPQQDVYNQYGNAYPATAAAATERRPAGGPQNQFPFQFGRDRVSAPPGSNAQQNMPPQMMGGPIQASAEVAQQGTMWQGRNDMTYNYANRQSTGSAPQGPTYHGVNRTDEMLHTDQRANHEGPWPSHGTRQPPYGPSAPVPPMTRPPPANYQPPPSMQNHIPQVSSPAPLPRPMENRTSPSKSPFLHSGMKMQKAGPPVPASHIAPAPVQPPLIRRDITFPPGSVEATQPVLKQRRRLTMKDIGTPEAWRVMMSLKSGLLAESTWALDTINILLYDDNSIMTFNLSQLPGLLELLVEYFRRCLIEIFGILKEYEVGDPGQRTLLDPGRFSKASSPAPVEGEEEEDLLGPKLEEEEEEEVIENDEEMAFSGKDKAASENSEEKLISKFDKLPVKIVQKNDPFVVDCSDKLGRVQEFDSGLLHWRIGGGDTTEHIQTHFESKTELLPSRPHVPCPPVPRKYVTAVEGTPGTAEQEGPPPDGPPEKRITATMDDMLSTRSSTLTEEGAKSVEATKESSKFPFGISPAQSHRNIKILEDEPHSKDETPLCTLLDWQDSLAKRCICVSNTIRSLSFVPGNDFEMSKHPGLLLILGKLILLHHKHPERKQAPLTYEKEEEQDQGVSCNKVEWWWDCLEMLRENTLVTLANISGQLDLSPYPESICLPVLDGLLHWAVCPSAEAQDPFSTLGPNAVLSPQRLVLETLSKLSIQDNNVDLILATPPFSRLEKLYSTMVRFLSDRKNPVCREMAVVLLANLAQGDSLAARAIAVQKGSIGNLLGFLEDSLAATQFQQSQASLLHMQNPPFEPTSVDMMRRAARALLALAKVDENHSEFTLYESRLLDISVSPLMNSLVSQVICDVLFLIGQS", "length": 2286 }, "evidence": [ { "id": "A0A8V0YQD7", "url": "https://omabrowser.org/oma/group/A0A8V0YQD7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A2BH40-1", "protein_name": "AT-rich interactive domain-containing protein 1A", "gene_name": "Arid1a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAQVAPAAASSLGNPPPPPSELKKAEQQQREEAGGEAAAAAAERGEMKAAAGQESEGPAVGPPQPLGKELQDGAESNGGGGGGGAGSGGGPGAEPDLKNSNGNAGPRPALNNNLPEPPGGGGGGGSSSSDGVGAPPHSAAAALPPPAYGFGQAYGRSPSAVAAAAAAVFHQQHGGQQSPGLAALQSGGGGGLEPYAGPQQNSHDHGFPNHQYNSYYPNRSAYPPPPQAYALSSPRGGTPGSGAAAAAGSKPPPSSSASASSSSSSFAQQRFGAMGGGGPSAAGGGTPQPTATPTLNQLLTSPSSARGYQGYPGGDYGGGPQDGGAGKGPADMASQCWGAAAAAAAAAAAVSGGAQQRSHHAPMSPGSSGGGGQPLARTPQSSSPMDQMGKMRPQPYGGTNPYSQQQGPPSGPQQGHGYPGQPYGSQTPQRYPMTMQGRAQSAMGSLSYAQQIPPYGQQGPSAYGQQGQTPYYNQQSPHPQQQPPYAQQPPSQTPHAQPSYQQQPQTQQPQLQSSQPPYSQQPSQPPHQQSPTPYPSQQSTTQQHPQSQPPYSQPQAQSPYQQQQPQQPASSSLSQQAAYPQPQPQQSQQTAYSQQRFPPPQELSQDSFGSQASSAPSMTSSKGGQEDMNLSLQSRPSSLPDLSGSIDDLPMGTEGALSPGVSTSGISSSQGEQSNPAQSPFSPHTSPHLPGIRGPSPSPVGSPASVAQSRSGPLSPAAVPGNQMPPRPPSGQSDSIMHPSMNQSSIAQDRGYMQRNPQMPQYTSPQPGSALSPRQPSGGQMHSGVGSYQQNSMGSYGPQGSQYGPQGGYPRQPNYNALPNANYPNAGMAGSMNPMGAGGQMHGQPGIPPYGTLPPGRMAHASMGNRPYGPNMANMPPQVGSGMCPPPGGMNRKTQESAVAMHVAANSIQNRPPGYPNMNQGGMMGTGPPYGQGINSMAGMINPQGPPYPMGGTMANNSAGMAASPEMMGLGDVKLTPATKMNNKADGTPKTESKSKKSSSSTTTNEKITKLYELGGEPERKMWVDRYLAFTEEKAMGMTNLPAVGRKPLDLYRLYVSVKEIGGLTQVNKNKKWRELATNLNVGTSSSAASSLKKQYIQCLYAFECKIERGEDPPPDIFAAADSKKSQPKIQPPSPAGSGSMQGPQTPQSTSSSMAEGGDLKPPTPASTPHSQIPPLPGMSRSNSVGIQDAFPDGSDPTFQKRNSMTPNPGYQPSMNTSDMMGRMSYEPNKDPYGSMRKAPGSDPFMSSGQGPNGGMGDPYSRAAGPGLGSVAMGPRQHYPYGGPYDRVRTEPGIGPEGNMGTGAPQPNLMPSTPDSGMYSPSRYPPQQQQQQQQQHDSYGNQFSTQGTPSSSPFPSQQTTMYQQQQQNYKRPMDGTYGPPAKRHEGEMYSVPYSAGQGQPQQQQLPAAQSQPASQPQAAQPSPQQDVYNQYSNAYPASATAATDRRPAGGPQNQFPFQFGRDRVSAPPGSSAQQNMPPQMMGGPIQASAEVAQQGTMWQGRNDMTYNYANRQNTGSATQGPAYHGVNRTDEMLHTDQRANHEGPWPSHGTRQPPYGPSAPVPPMTRPPPSNYQPPPSMPNHIPQVSSPAPLPRPMENRTSPSKSPFLHSGMKMQKAGPPVPASHIAPTPVQPPMIRRDITFPPGSVEATQPVLKQRRRLTMKDIGTPEAWRVMMSLKSGLLAESTWALDTINILLYDDNSIMTFNLSQLPGLLELLVEYFRRCLIEIFGILKEYEVGDPGQRTLLDPGRFTKVYSPAHTEEEEEEHLDPKLEEEEEEGVGNDEEMAFLGKDKPSSENNEEKLVSKFDKLPVKIVQRNDPFVVDCSDKLGRVQEFDSGLLHWRIGGGDTTEHIQTHFESKIELLPSRPYVPCPTPPRKHLTTVEGTPGTTEQEGPPPDGLPEKRITATMDDMLSTRSSTLTDEGAKSAEATKESSKFPFGISPAQSHRNIKILEDEPHSKDETPLCTLLDWQDSLAKRCVCVSNTIRSLSFVPGNDFEMSKHPGLLLILGKLILLHHKHPERKQAPLTYEKEEEQDQGVSCDKVEWWWDCLEMLRENTLVTLANISGQLDLSPYPESICLPVLDGLLHWAVCPSAEAQDPFSTLGPNAVLSPQRLVLETLSKLSIQDNNVDLILATPPFSRLEKLYSTMVRFLSDRKNPVCREMAVVLLANLAQGDSLAARAIAVQKGSIGNLLGFLEDSLAATQFQQSQASLLHMQNPPFEPTSVDMMRRAARALLALAKVDENHSEFTLYESRLLDISVSPLMNSLVSQVICDVLFLIGQS", "length": 2283 }, "evidence": [ { "id": "A0A8V0YQD7", "url": "https://omabrowser.org/oma/group/A0A8V0YQD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D4A3E3-1", "protein_name": "AT-rich interaction domain 1A", "gene_name": "Arid1a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAAQVAPAAASSLGNPPPPPSELKKAEQQQREEAGGEAAAAAAERGEMKAAAGQESEGPAVGPPQPLGKELQDGAESNGGGGGGGAGSGGGPGAEPDLKNSNGNAGPRPALNNNLTEPPGGGGGSSDGVGAPPHSAAAALPPPAYGFGQPYGRSPSAVAAAAAAVFHQQHGGQQSPGLAALQSGGGGGLEPYAGPQQNSHDHGFPNHQYNSYYPNRSAYPPPPQAYALSSPRGGTPGSGAAAAGSKPPPSSSASASSSSSSFAPQRFGAMGGGGPSAAGGGTPQPTATPTLNQLLTSPSSARGYQGYPGGDYGGGPQDGGAGKGPADMASQCWGAAAAAAAAAAASGGAQQRSHHAPMSPGSSGGGGQPLARTPQSSSPMDQMGKMRPQPYGGTNPYSQQQGPPSGPQQGHGYPGQPYGSQTPQRYPMTMQGRAQSAMGSLSYAQQIPPYGQQGPSAYGQQGQTPYYNQQSPHPQQQQQPPYSQQPPSQTPHAQPSYQQQPQTQQPQLQSSQPPYSQQPSQPPHQQSQTPYPSQQSTTQQHPQSQPPYSQPQAQAPYQQQQPQQPASSTLSQQAAYPQPQPQQSQQTAYSQQRFPPPQELSQDSFGSQASSAPSMTSSKGGQEDMNLSLQSRPSSLPDLSGSIDDLPMGTEGALSPGVSTSGISSSQGEQSNPAQSPFSPHTSPHLPGIRGPSPSPVGSPASVAQSRSGPLSPAAVPGNQMPPRPPSGQSDSIMHPSMNQSSIAQDRGYMQRNPQMPQYTSPQPGSALSPRQPSGGQMHSGMGSYQQNSMGSYGPQGSQYGPQGGYPRQPNYNALPNANYPSAGMAGSMNPLGAGGQMHGQPGIPPYGTLPPGRMTHASMGNRPYGPNMANMPPQVGSGMCPPPGGMNRKTQESAVAMHVAANSIQNRPPGYPNMNQGGIMGTGPPYGQGINSMAGMINPQGPPYPMGGTMANNSAGMAASPEMMGLGDVKLTPATKMNNKADGTPKTESKSKKSSSSTTTNEKITKLYELGGEPERKMWVDRYLAFTEEKAMGMTNLPAVGRKPLDLYRLYVSVKEIGGLTQVNKNKKWRELATNLNVGTSSSAASSLKKQYIQCLYAFECKIERGEDPPPDIFAAADSKKSQPKIQPPSPAGSGSMQGPQTPQSTSSSMAEGGDLKPPTPASTPHSQIPPLPGMSRSNSVGIQDAFPDGSEPTFQKRNSMTPNPGYQPSMNTSDMMGRMSYEPNKDPYGGMRKAPGSDPFMSSGQGPNGGMGDPYSRAAGPGLGNVAMGPRQHYPYGGPYDRVRTEPGIGPEGNMGTGAPQPNLMPSTPDSGMYSPSRYPPQQQQQQQQQQQQQQQQQQRHDSYGNQFSTQGTPSSSPFPSQQTTMYQQQQQQNYKRPMDGTYGPPAKRHEGELYSVPYSTGQGQPQQQQLPAAQSQSASQPQAAQPSPQQDVYNQYSNAYPATATAATERRPAGGPQNQFPFQFGRDRVSAPPGSNAQQNMPPQMMGGPIQASAEVAQQGTMWQGRNDMTYNYANRQNTGSAPQGPAYHGVNRTDEMLHTDQRANHEGPWPSHGTRQPPYGPSAPVPPMTRPPPSNYQPPPSMQNHIPQVSSPAPLPRPMENRTSPSKSPFLHSGMKMQKAGPPVPASHIAPTPVQPPMIRRDITFPPGSVEATQPVLKQRRRLTMKDIGTPEAWRVMMSLKSGLLAESTWALDTINILLYDDNSIMTFNLSQLPGLLELLVEYFRRCLIEIFGILKEYEVGDPGQRTLLDPGRLTKVSSPAPTEEEEEEEHVDPKLEEEEEEGVENDEEMAFLGKDKPPSEKSEEKLVSKFDKLPVKIVQKNDPFVVDCSDKLGRVQEFDSGLLHWRIGGGDTTEHIQTHFESKIELLPSRPCVPSPVPPRKHVTTVEGTPGTTEQEGPPPDGLPEKRITATMDDMLSTRSSTLTDEGTKSTEANKESSKFPFGISPAQSHRNIKILEDEPHSKDETPLCTLLDWQDSLAKRCVCVSNAIRSLSFVPGNDFEMSKHPGLLLILGKLILLHHKHPERKQAPLTYEKEEEQDQGVSCDKVEWWWDCLEMLRENTLVTLANISGQLDLSPYPESICLPVLDGLLHWAVCPSAEAQDPFSTLGPNAVLSPQRLVLETLSKLSIQDNNVDLILATPPFSRLEKLYSTMVRFLSDRKNPVCREMAVVLLANLAQGDSLAARAIAVQKGSIGNLLGFLEDSLAATQFQQSQASLLHMQSPPFEPTSVDMMRRAARALLALAKVDENHSEFTLYESRLLDISVSPLMNSLVSQVICDVLFLIGQS", "length": 2291 }, "evidence": [ { "id": "A0A8V0YQD7", "url": "https://omabrowser.org/oma/group/A0A8V0YQD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O14497-1", "protein_name": "AT-rich interactive domain-containing protein 1A", "gene_name": "ARID1A", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": 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"MNEKIKSPQTQQQQQGGAPAPAATPPSAGAAPGAATPPTSGPPTPNNNSNNGSDPSIQQQQQNVAPHPYGAPPPPGSGPGGPPGPDPAAVMHYHHLHQQQQQHPPPPHMQQQQHHGGPAPPPPGGAPEHAPGVKEEYTHLPPPHPHPAYGRYHADPNMDPYRYGQPLPGGKPPQQQQPHPQQQPPQQPGPGGSPNRPPQQRYIPGQPPQGPTPTLNSLLQSSNPPPPPQHRYANTYDPQQAAASAAAAAAAQQQQAGGPPPPGHGPPPPQHQPSPYGGQQGGWAPPPRPYSPQLGPSQQYRTPPPTNTSRGQSPYPPAHGQNSGSYPSSPQQQQQQQQQQQQQAGQQPGGPVPGGPPPGTGQQPPQQNTPPTSQYSPYPQRYPTPPGLPAGGSNHRTAYSTHQYPEPNRPWPGGSSPSPGSGHPLPPASPHHVPPLQQQPPPPPHVSAGGPPPSSSPGHAPSPSPQPSQASPSPHQELIGQNSNDSSSGGAHSGMGSGPPGTPNPQQVMRPTPSPTGSSGSRSMSPAVAQNHPISRPASNQSSSGGPMQQPPVGAGGPPPMPPHPGMPGGPPQQQQSQQQQASNSASSASNSPQQTPPPAPPPNQGMNNMATPPPPPQGAAGGGYPMPPHMHGGYKMGGPGQSPGAQGYPPQQPQQYPPGNYPPRPQYPPGAYATGPPPPPTSQAGAGGANSMPSGAQAGGYPGRGMPNHTGQYPPYQWVPPSPQQTVPGGAPGGAMVGNHVQGKGTPPPPVVGGPPPPQGSGSPRPLNYLKQHLQHKGGYGGSPTPPQGPQGYGNGPTGMHPGMPMGPPHHMGPPHGPTNMGPPTSTPPQSQMLQGGQPQGQGASGGPESGGPEHISQDNGISSSGPTGAAGMHAVTSVVTTGPDGTSMDEVSQQSTLSNASAASGEDPQCTTPKSRKNDPYSQSHLAPPSTSPHPVVMHPGGGPGEEYDMSSPPNWPRPAGSPQVFNHVPVPQEPFRSTITTTKKSDSLCKLYEMDDNPDRRGWLDKLRAFMEERRTPITACPTISKQPLDLYRLYIYVKERGGFVEVTKSKTWKDIAGLLGIGASSSAAYTLRKHYTKNLLTFECHFDRGDIDPLPIIQQVEAGSKKKTAKAASVPSPGGGHLDAGTTNSTGSSNSQDSFPAPPGSAPNAAIDGYPGYPGGSPYPVASGPQPDYATAGQMQRPPSQNNPQTPHPGAAAAVAAGDNISVSNPFEDPIAAGGGPGSGTGPGPGQGPGPGAASGGAGAVGAVGGGPQPHPPPPHSPHTAAQQAAGQHQQQHPQHQHPGLPGPPPPQQQQGQQGQQPPPSVGGGPPPAPQQHGPGQVPPSPQQHVRPAAGAPYPPGGSGYPTPVSRTPGSPYPSQPGAYGQYGSSDQYNATGPPGQPFGQGPGQYPPQNRNMYPPYGPEGEAPPTGANQYGPYGSRPYSQPPPGGPQPPTQTVAGGPPAGGAPGAPPSSAYPTGRPSQQDYYQPPPDQSPQPRRHPDFIKDSQPYPGYNARPQIYGAWQSGTQQYRPQYPSSPAPQNWGGAPPRGAAPPPGAPHGPPIQQPAGVAQWDQHRYPPQQGPPPPPQQQQQPQQQQQQPPYQQVAGPPGQQPPQAPPQWAQMNPGQTAQSGIAPPGSPLRPPSGPGQQNRMPGMPAQQQQSQQQGGVPQPPPQQASHGGVPSPGLPQVGPGGMVKPPYAMPPPPSQGVGQQVGQGPPGGMMSQKPPPMPGQAMQQQPLQQQPPSHQHPHPHQHPQHQHPHQMPPNQTAPGGYGPPGMPGGGAQLVKKELIFPHDSVESTTPVLYRRKRLMKADVCPVDPWRIFMAMRSGLLTECTWALDVLNVLLFDDSTVQFFGISNLPGLLTLLLEHFQKNLAEMFDERENEEQSALLAEDADDDADSGTVMCEKLRTSGRQPRCVRSISSYNRRRHYENMDRSGKDGAGNGSDSEDADEGIDLGQVRVQPNPEERSLLLSFTPNYTMVTRKGVPVRIQPAENDIFVDERQKAWDIDTNRLYEQLEPVGSDAWTYGFTEPDPLDGIIDVFKSEIVNIPFARYIRSDKKGRKRTELASSSRKPEIKTEENSTEEQTFNKKRRLVSGGSSSSGAHAEGKKSKLTSEEFAQPNAEVKKEPGTADSDCRPVDMDIEAPQQRLTNGVAPCSSTPAIFDPRTTAKDEARVLQRRRDSSFEDECYTRDEASLHLVSESQDSLARRCIALSNIFRNLTFVPGNETVLAKSTRFLAVLGRLLLLNHEHLRRTPKTRNYDREEDTDFSDSCSSLQGEREWWWDYLITIRENMLVAMANIAGHLELSRYDELIARPLIDGLLHWAVCPSAHGQDPFPSCGPNSVLSPQRLALEALCKLCVTDANVDLVIATPPFSRLEKLCAVLTRHLCRNEDQVLREFSVNLLHYLAAADSAMARTVALQSPCISYLVAFIEQAEQTALGVANQHGINYLRENPDSMGTSLDMLRRAAGTLLHLAKHPDNRSLFMQQEQRLLGLVMSHILDQQVALIISRVLYQVSRGTGPIHSVEFRLLQQRQQQQLRPGPAGKQAASAGGSATVKAETASTETSSTEAKPAPAATTAVVNDENSNSSQQLPPAATFNDVSNSSTNSNSCGTASSNQTNNSTTNSSHSSSAISSQSAITVAAPSAAATGAGSATAAAIASDQQQVSKVAAAAAAAAALSNASAAAAAAAAAAAASVGPPTSSSVSAGAAVAQPAAPPPTNAGTTTAVA", "length": 2716 }, "evidence": [ { "id": "A0A8V0YQD7", "url": "https://omabrowser.org/oma/group/A0A8V0YQD7/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQD7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQD7" } ], "pmid": "" }, { "name": "transcription coactivator activity", "id": "GO:0003713", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003713", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQD7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQD7" } ], "pmid": "" }, { "name": "nuclear receptor binding", "id": "GO:0016922", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016922", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQD7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQD7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQD7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQD7" } ], "pmid": "" }, { "name": "SWI/SNF complex", "id": "GO:0016514", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016514", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQD7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQD7" } ], "pmid": "" }, { "name": "brahma complex", "id": "GO:0035060", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035060", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQD7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQD7" } ], "pmid": "" }, { "name": "nBAF complex", "id": "GO:0071565", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071565", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQD7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQD7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "chromatin remodeling", "id": "GO:0006338", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006338", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQD7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQD7" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQD7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQD7" } ], "pmid": "" }, { "name": "nervous system development", "id": "GO:0007399", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007399", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQD7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQD7" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQD7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQD7" } ], "pmid": "" }, { "name": "positive regulation of DNA-templated transcription", "id": "GO:0045893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045893", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQD7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQD7" } ], "pmid": "" }, { "name": "nucleosome disassembly", "id": "GO:0006337", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006337", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQD7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQD7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1220, "end_pos": 1222, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1593, "end_pos": 1595, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1701, "end_pos": 1703, "annotation": "n_glycosylation_sequon" }, { 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{ "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1220, "end_pos": 1222 }, { "start_pos": 1593, "end_pos": 1595 }, { "start_pos": 1701, "end_pos": 1703 }, { "start_pos": 2058, "end_pos": 2060 }, { "start_pos": 2239, "end_pos": 2241 }, { "start_pos": 746, "end_pos": 748 }, { "start_pos": 961, "end_pos": 963 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 45 }, { "field": "total_sites", "count": 38 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 38 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 37 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 2 }, { 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Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052572.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015135597.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015135597", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015135597" } ] }, { "annotation": "Member of the NMDAR signaling complex that may play a role in control of AMPAR potentiation and synaptic plasticity in excitatory synapses. 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"https://www.genome.jp/dbget-bin/www_bget?gga:427360", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YNJ7", "url": "https://www.orthodb.org/?gene=A0A8V0YNJ7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YNK7", "url": "https://www.orthodb.org/?gene=A0A8V0YNK7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YV08", "url": "https://www.orthodb.org/?gene=A0A8V0YV08", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YV13", "url": "https://www.orthodb.org/?gene=A0A8V0YV13", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YV19", "url": "https://www.orthodb.org/?gene=A0A8V0YV19", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YV31", "url": "https://www.orthodb.org/?gene=A0A8V0YV31", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YX06", "url": "https://www.orthodb.org/?gene=A0A8V0YX06", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YX16", "url": "https://www.orthodb.org/?gene=A0A8V0YX16", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR19964", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19964", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19964:SF10", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19964:SF10", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00595", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00595", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF09045", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09045", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16667", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16667", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015135597", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015135597", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YNJ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNJ7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YNJ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNJ7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YNK7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNK7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YNK7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNK7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YV08", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YV08", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YV08-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YV08-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YV13", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YV13", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YV13-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YV13-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YV19", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YV19", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YV19-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YV19-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YV31", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YV31", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YV31-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YV31-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YX06", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YX06", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YX06-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YX06-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YX16", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YX16", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YX16-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YX16-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLETIDTHRALQAVERLQAKLRDRGDIANEEKLNLLKSVLQSPLFNQILNLQTSVQQLRDQVNITPSVHSTGEFPQLLHHGVNVGSLPHNESYLLAQQNGSPANVLEASMRSITPQINGKSSSDDFEQLIRSMSQGRPVETIELIKPLSGGLGFSVVGLKSENRGELGIFVQEIQEGSVAHRDGKLKEADQILAINGQALDQTITHQQAISILQKAKDNVQLVVARGNFPQLISPVVSRSPSAASTVSAHSNPVHWQHVETIELVNDGSGLGFGIVGGKSTGVIVKTILPGGVADQHGRLCSGDHILKIGDTDLTGMSSEQVAQVLRQCGNRVKLVIARGPVEEPPPPAVPPGTPVPITTTEKQTDVSVDSCEEGEKFNVELTKNTQGLGITIAGYIGDKTSEPSGIFVKSITKGSAVEQDGRIHVGDQIIVVDGTNLQGFTNQQAVDVLRHTGQTVRLTLIRRGLKQENYIQPQEDFSAAVERDLMLQTVDSSTAKDSSEPEQGSPSQPCSGSAVNIREDIKQQETDFQLSATEEEAMKAKWQRIMGSNYEIVVAVVSKFSESSGLGISLEATVGHHFIRSILPEGPVGRSGKLFSGDELLEVNEISLLGENHKDVVNILKELPIKVTMVCCRPVASSVSHTEVLENLSLSEVQLAEKAHIDLGFIGSSNTEETALEISTAQTMEEVQNSSFTMWEAEVQHTELEKGSMGLGFSILDYQDPVDPSKTIILIRSLVPGGVAEQDGRLSPGDRLMFVNDISLENGSLEEAVQALKGAPVGAVKIGVAKPLPLSPEEGCVSAKEDCFFYTAQSLEEEGPADAALFHAELALVDSSGAGLAVEPSFESQLAPENLTFPTSSPAASDSFCSEDLNFGVPFSASTPKIAGKEYLSYADDNDISTESSYSMDLSERGREQSAAEDRSLEATATFSDETFLSEDIFDIKHDKEVVTESSLILPVNKDFTISKMIKNIFEKTITIAKGNSSLGMTVSSDKDGTGMIVRSVIHGGSISRDGRINVGDCILSINEESSTNLTNAQARAMLRRHSLSGPEIRSSPAPSDDQALFYVITYVLAENLPKYRASLEQQSEETMSVISSSQSASIREIPELPEREEGEGEESELQNAAFSNWNQPRKVELWREPGKSLGISIVGGRGMGSRLSSGEVMRGIFIKHILEDSPAGKNGTLKTGDRIVEVDGIDLRDASHEQAVEAIRKAGNPVVFMVQSIISRSRPESLYSPSSASALCEQKTTNPFYHQSSKNSSLPFPQNYLFCRPAIFSSTNPFADSSQFNANKEVSNPIRVTFRCSPTNPFAPTPFKAFGQSTSEPEKTSFCNLPLPPPSTFLGINSDVAQSSSSQVTEDVEKENEFGYSWKKITQRYGSLPGELHMIELEKGRTGLGLSLAGNKDRSRMSVFVVGIDPNGAAGKDGRLQIADELLEINGQILYGRTHQNASSIIKCAPSKVKIIFIRNKDAVNQMAVCPAKSIEALPCASETLQNQEIDTTADGGVSPDFSSYKNIQYVELPKDEGGLGIAISEEDTDSGVVIKSLTDHGAAAKDGRIKIGTQILAVDDEIVVGYPVEKFINLLKSSKNMVKLTVNSAESDSQTIAPVLSSAAPGERRNIHPPTAICSSNSPEPEPVKNTSRSSTPATLASDPATCPIIPGCETTIDISKGQTGLGLSIVGGADTLLGAIIIHEVYEEGAASKDGRLWAGDQILEVNGIDLRSATHDEAINVLRQTPQKVRLTVYRDEAQYKEEDMYDVVVIELQKKPGKGLGLSIVGKRNDTGVFVSDIVKGGIADTDGRLMQGDQILTVNGEDVRNTNQEAVAALLKCSLGTVRLEVGRIKAGPFHSERRTSQSSQVSEGSGSLSSFSISASASSTPEVFESGLKRNTASSEIQGLRTVEIKKGPADSLGVSIAGGVGSPLGDIPIFIAMMHPNGVAAQTQKLRVGDRIVSICGTSTEGMTHSQAVSILKNASGTIELQVVAGGDVSVITGQQQDPPTSSLSLAGLTSTSIFQDDLGPPQYKTITLERGPDGLGFSIVGGYGSPHGDLPIYVKTVFAKGAAAEDGRLKRGDQIIAVNGQSLEGVTHEEAVAILKRTKGTVTLTVLS", "length": 2106, "header": "tr|A0A8V0YNJ7-1|A0A8V0YNJ7_CHICK Isoform 1 of Multiple PDZ domain protein OS=Gallus gallus OX=9031 GN=MPDZ PE=1 SV=1 CANONICAL=A0A8V0YNJ7-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YNJ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNJ7/entry#A0A8V0YNJ7-1", "sequence": { "sequence": "MLETIDTHRALQAVERLQAKLRDRGDIANEEKLNLLKSVLQSPLFNQILNLQTSVQQLRDQVNITPSVHSTGEFPQLLHHGVNVGSLPHNESYLLAQQNGSPANVLEASMRSITPQINGKSSSDDFEQLIRSMSQGRPVETIELIKPLSGGLGFSVVGLKSENRGELGIFVQEIQEGSVAHRDGKLKEADQILAINGQALDQTITHQQAISILQKAKDNVQLVVARGNFPQLISPVVSRSPSAASTVSAHSNPVHWQHVETIELVNDGSGLGFGIVGGKSTGVIVKTILPGGVADQHGRLCSGDHILKIGDTDLTGMSSEQVAQVLRQCGNRVKLVIARGPVEEPPPPAVPPGTPVPITTTEKQTDVSVDSCEEGEKFNVELTKNTQGLGITIAGYIGDKTSEPSGIFVKSITKGSAVEQDGRIHVGDQIIVVDGTNLQGFTNQQAVDVLRHTGQTVRLTLIRRGLKQENYIQPQEDFSAAVERDLMLQTVDSSTAKDSSEPEQGSPSQPCSGSAVNIREDIKQQETDFQLSATEEEAMKAKWQRIMGSNYEIVVAVVSKFSESSGLGISLEATVGHHFIRSILPEGPVGRSGKLFSGDELLEVNEISLLGENHKDVVNILKELPIKVTMVCCRPVASSVSHTEVLENLSLSEVQLAEKAHIDLGFIGSSNTEETALEISTAQTMEEVQNSSFTMWEAEVQHTELEKGSMGLGFSILDYQDPVDPSKTIILIRSLVPGGVAEQDGRLSPGDRLMFVNDISLENGSLEEAVQALKGAPVGAVKIGVAKPLPLSPEEGCVSAKEDCFFYTAQSLEEEGPADAALFHAELALVDSSGAGLAVEPSFESQLAPENLTFPTSSPAASDSFCSEDLNFGVPFSASTPKIAGKEYLSYADDNDISTESSYSMDLSERGREQSAAEDRSLEATATFSDETFLSEDIFDIKHDKEVVTESSLILPVNKDFTISKMIKNIFEKTITIAKGNSSLGMTVSSDKDGTGMIVRSVIHGGSISRDGRINVGDCILSINEESSTNLTNAQARAMLRRHSLSGPEIRSSPAPSDDQALFYVITYVLAENLPKYRASLEQQSEETMSVISSSQSASIREIPELPEREEGEGEESELQNAAFSNWNQPRKVELWREPGKSLGISIVGGRGMGSRLSSGEVMRGIFIKHILEDSPAGKNGTLKTGDRIVEVDGIDLRDASHEQAVEAIRKAGNPVVFMVQSIISRSRPESLYSPSSASALCEQKTTNPFYHQSSKNSSLPFPQNYLFCRPAIFSSTNPFADSSQFNANKEVSNPIRVTFRCSPTNPFAPTPFKAFGQSTSEPEKTSFCNLPLPPPSTFLGINSDVAQSSSSQVTEDVEKENEFGYSWKKITQRYGSLPGELHMIELEKGRTGLGLSLAGNKDRSRMSVFVVGIDPNGAAGKDGRLQIADELLEINGQILYGRTHQNASSIIKCAPSKVKIIFIRNKDAVNQMAVCPAKSIEALPCASETLQNQEIDTTADGGVSPDFSSYKNIQYVELPKDEGGLGIAISEEDTDSGVVIKSLTDHGAAAKDGRIKIGTQILAVDDEIVVGYPVEKFINLLKSSKNMVKLTVNSAESDSQTIAPVLSSAAPGERRNIHPPTAICSSNSPEPEPVKNTSRSSTPATLASDPATCPIIPGCETTIDISKGQTGLGLSIVGGADTLLGAIIIHEVYEEGAASKDGRLWAGDQILEVNGIDLRSATHDEAINVLRQTPQKVRLTVYRDEAQYKEEDMYDVVVIELQKKPGKGLGLSIVGKRNDTGVFVSDIVKGGIADTDGRLMQGDQILTVNGEDVRNTNQEAVAALLKCSLGTVRLEVGRIKAGPFHSERRTSQSSQVSEGSGSLSSFSISASASSTPEVFESGLKRNTASSEIQGLRTVEIKKGPADSLGVSIAGGVGSPLGDIPIFIAMMHPNGVAAQTQKLRVGDRIVSICGTSTEGMTHSQAVSILKNASGTIELQVVAGGDVSVITGQQQDPPTSSLSLAGLTSTSIFQDDLGPPQYKTITLERGPDGLGFSIVGGYGSPHGDLPIYVKTVFAKGAAAEDGRLKRGDQIIAVNGQSLEGVTHEEAVAILKRTKGTVTLTVLS", "length": 2106, "header": "tr|A0A8V0YNJ7-1|A0A8V0YNJ7_CHICK Isoform 1 of Multiple PDZ domain protein OS=Gallus gallus OX=9031 GN=MPDZ PE=1 SV=1 CANONICAL=A0A8V0YNJ7-1" }, "locus": { "chromosome": "Z", "start_pos": 31490983, "end_pos": 31399485, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010039098.1", "url": "https://www.ensembl.org/id/ENSGALT00010039098.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010022582.1", "url": "https://www.ensembl.org/id/ENSGALP00010022582.1" } ] } }, { "isoform_ac": "A0A8V0YNK7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNJ7/entry#A0A8V0YNK7-1", "sequence": { "sequence": "MLETIDTHRALQAVERLQAKLRDRGDIANEEKLNLLKSVLQSPLFNQILNLQTSVQQLRDQVNITPSVHSTGEFPQLLHHGVNVGSLPHNESYLLAQQNGSPANVLEASMRSITPQINGKSSSDDFEQLIRSMSQGRPVETIELIKPLSGGLGFSVVGLKSENRGELGIFVQEIQEGSVAHRDGKLKEADQILAINGQALDQTITHQQAISILQKAKDNVQLVVARGNFPQLISPVVSRSPSAASTVSAHSNPVHWQHVETIELVNDGSGLGFGIVGGKSTGVIVKTILPGGVADQHGRLCSGDHILKIGDTDLTGMSSEQVAQVLRQCGNRVKLVIARGPVEEPPPPAVPPGTPVPITTTEKQTDVSVDSCEEGEKFNVELTKNTQGLGITIAGYIGDKTSEPSGIFVKSITKGSAVEQDGRIHVGDQIIVVDGTNLQGFTNQQAVDVLRHTGQTVRLTLIRRGLKQENYIQPQEDFSAAVERDLMLQTVDSSTAKDSSEPEQGSPSQPCSGSAVNIREDIKQQETDFQLSATEEEAMKAKWQRIMGSNYEIVVAVVSKFSESSGLGISLEATVGHHFIRSILPEGPVGRSGKLFSGDELLEVNEISLLGENHKDVVNILKELPIKVTMVCCRPVASSVSHTEVLENLSLSEVQLAEKAHIDLGFIGSSNTEETALEISTAQTMEEVQNSSFTMWEAEVQHTELEKGSMGLGFSILDYQDPVDPSKTIILIRSLVPGGVAEQDGRLSPGDRLMFVNDISLENGSLEEAVQALKGAPVGAVKIGVAKPLPVDSSGAGLAVEPSFESQLAPENLTFPTSSPAASDSFCSEDLNFGVPFSASTPKIAGKEYLSYADDNDISTESSYSMDLSERGREQSAAEDRSLEATATFSDETFLSEDIFDIKHDKEVVTESSLILPVNKDFTISKMIKNIFEKTITIAKGNSSLGMTVSSDKDGTGMIVRSVIHGGSISRDGRINVGDCILSINEESSTNLTNAQARAMLRRHSLSGPEIRSSPAPSDDQALFYVITYVLAENLPKYRASLEQQSEETMSVISSSQSASIREIPELPEREEGEGEESELQNAAFSNWNQPRKVELWREPGKSLGISIVGGRGMGSRLSSGEVMRGIFIKHILEDSPAGKNGTLKTGDRIVEVDGIDLRDASHEQAVEAIRKAGNPVVFMVQSIISRSRPESLYSPSSASALCEQKTTNPFYHQSSKAFGQSTSEPEKTSFCNLPLPPPSTFLGINSDVAQSSSSQVTEDVEKENEFGYSWKKITQRYGSLPGELHMIELEKGRTGLGLSLAGNKDRSRMSVFVVGIDPNGAAGKDGRLQIADELLEINGQILYGRTHQNASSIIKCAPSKVKIIFIRNKDAVNQMAVCPAKSIEALPCASETLQNQEIDTTADGGVSPDFSSYKNIQYVELPKDEGGLGIAISEEDTDSGVVIKSLTDHGAAAKDGRIKIGTQILAVDDEIVVGYPVEKFINLLKSSKNMVKLTVNSAESDSQTIAPVLSSAAPGERRNIHPPTAICSSNSPEPEPVKNTSRSSTPATLASDPATCPIIPGCETTIDISKGQTGLGLSIVGGADTLLGAIIIHEVYEEGAASKDGRLWAGDQILEVNGIDLRSATHDEAINVLRQTPQKVRLTVYRDEAQYKEEDMYDVVVIELQKKPGKGLGLSIVGKRNDTGVFVSDIVKGGIADTDGRLMQGDQILTVNGEDVRNTNQEAVAALLKCSLGTVRLEVGRIKAGPFHSERRTSQSSQVSEGSGSLSSFSISASASSTPEVFESGLKRNTASSEIQGLRTVEIKKGPADSLGVSIAGGVGSPLGDIPIFIAMMHPNGVAAQTQKLRVGDRIVSICGTSTEGMTHSQAVSILKNASGTIELQVVAGGDVSVITGQQQDPPTSSLSLAGLTSTSIFQDDLGPPQYKTITLERGPDGLGFSIVGGYGSPHGDLPIYVKTVFAKGAAAEDGRLKRGDQIIAVNGQSLEGVTHEEAVAILKRTKGTVTLTVLS", "length": 2009, "header": "tr|A0A8V0YNK7-1|A0A8V0YNK7_CHICK Computationally mapped isoform of Multiple PDZ domain protein OS=Gallus gallus OX=9031 GN=MPDZ PE=1 SV=1 CANONICAL=A0A8V0YNJ7-1" }, "locus": { "chromosome": "Z", "start_pos": 31490983, "end_pos": 31399485, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010039128.1", "url": "https://www.ensembl.org/id/ENSGALT00010039128.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010022592.1", "url": "https://www.ensembl.org/id/ENSGALP00010022592.1" } ] } }, { "isoform_ac": "A0A8V0YV08-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNJ7/entry#A0A8V0YV08-1", "sequence": { "sequence": "MLETIDTHRALQAVERLQAKLRDRGDIANEEKLNLLKSVLQSPLFNQILNLQTSVQQLRDQVNITPSVHSTGEFPQLLHHGVNVGSLPHNESYLLAQQNGSPANVLEASMRSITPQINGKSSSDDFEQLIRSMSQGRPVETIELIKPLSGGLGFSVVGLKSENRGELGIFVQEIQEGSVAHRDGKLKEADQILAINGQALDQTITHQQAISILQKAKDNVQLVVARGNFPQLISPVVSRSPSAASTVSAHSNPVHWQHVETIELVNDGSGLGFGIVGGKSTGVIVKTILPGGVADQHGRLCSGDHILKIGDTDLTGMSSEQVAQVLRQCGNRVKLVIARGPVEEPPPPAVPPGTPVPITTTEKQTDVSVDSCEEGEKFNVELTKNTQGLGITIAGYIGDKTSEPSGIFVKSITKGSAVEQDGRIHVGDQIIVVDGTNLQGFTNQQAVDVLRHTGQTVRLTLIRRGLKQENYIQPQEDFSAAVERDLMLQTVDSSTAKDSSEPEQGSPSQPCSGSAVNIREDIKQQETDFQLSATEEEAMKAKWQRIMGSNYEIVVAVVSKFSESSGLGISLEATVGHHFIRSILPEGPVGRSGKLFSGDELLEVNEISLLGENHKDVVNILKELPIKVTMVCCRPVASSVSHTEVLENLSLSEVQLAEKAHIDLGFIGSSNTEETALEISTAQTMEEVQNSSFTMWEAEVQHTELEKGSMGLGFSILDYQDPVDPSKTIILIRSLVPGGVAEQDGRLSPGDRLMFVNDISLENGSLEEAVQALKGAPVGAVKIGVAKPLPLSPEEGCVSAKEDCFFYTAQSLEEEGPADAALFHAELALVDSSGAGLAVEPSFESQLAPENLTFPTSSPAASDSFCSEDLNFGVPFSASTPKIAGKEYLSYADDNDISTESSYSMDLSERGREQSAAEDRSLEATATFSDETFLSEDIFDIKHDKEVVTESSLILPVNKDFTISKMIKNIFEKTITIAKGNSSLGMTVSSDKDGTGMIVRSVIHGGSISRDGRINVGDCILSINEESSTNLTNAQARAMLRRHSLSGPEIRSSPAPSDDQALFYVITYVLAENLPKYRASLEQQSEETMSVISSSQSASIREIPELPEREEGEGEESELQNAAFSNWNQPRKVELWREPGKSLGISIVGGRGMGSRLSSGEVMRGIFIKHILEDSPAGKNGTLKTGDRIVEVDGIDLRDASHEQAVEAIRKAGNPVVFMVQSIISRSRAFGQSTSEPEKTSFCNLPLPPPSTFLGINSDVAQSSSSQVTEDVEKENEFGYSWKKITQRYGSLPGELHMIELEKGRTGLGLSLAGNKDRSRMSVFVVGIDPNGAAGKDGRLQIADELLEINGQILYGRTHQNASSIIKCAPSKVKIIFIRNKDAVNQMAVCPAKSIEALPCASETLQNQEIDTTADGGVSPDFSSYKNIQYVELPKDEGGLGIAISEEDTDSGVVIKSLTDHGAAAKDGRIKIGTQILAVDDEIVVGYPVEKFINLLKSSKNMVKLTVNSAESDSQTIAPVLSSAAPGERRNIHPPTAICSSNSPEPEPVKNTSRSSTPATLASDPATCPIIPGCETTIDISKGQTGLGLSIVGGADTLLGAIIIHEVYEEGAASKDGRLWAGDQILEVNGIDLRSATHDEAINVLRQTPQKVRLTVYRDEAQYKEEDMYDVVVIELQKKPGKGLGLSIVGKRNDTGVFVSDIVKGGIADTDGRLMQGDQILTVNGEDVRNTNQEAVAALLKCSLGTVRLEVGRIKAGPFHSERRTSQSSQVSEGSGSLSSFSISASASSTPEVFESGLKRNTASSEIQGLRTVEIKKGPADSLGVSIAGGVGSPLGDIPIFIAMMHPNGVAAQTQKLRVGDRIVSICGTSTEGMTHSQAVSILKNASGTIELQVVAGGDVSVITGQQQDPPTSSLSLAGLTSTSIFQDDLGPPQYKTITLERGPDGLGFSIVGGYGSPHGDLPIYVKTVFAKGAAAEDGRLKRGDQIIAVNGQSLEGVTHEEAVAILKRTKGTVTLTVLS", "length": 2020, "header": "tr|A0A8V0YV08-1|A0A8V0YV08_CHICK Computationally mapped isoform of Multiple PDZ domain protein OS=Gallus gallus OX=9031 GN=MPDZ PE=1 SV=1 CANONICAL=A0A8V0YNJ7-1" }, "locus": { "chromosome": "Z", "start_pos": 31490983, "end_pos": 31399485, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010039118.1", "url": "https://www.ensembl.org/id/ENSGALT00010039118.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010022589.1", "url": "https://www.ensembl.org/id/ENSGALP00010022589.1" } ] } }, { "isoform_ac": "A0A8V0YV13-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNJ7/entry#A0A8V0YV13-1", "sequence": { "sequence": "MLETIDTHRALQAVERLQAKLRDRGDIANEEKLNLLKSVLQSPLFNQILNLQTSVQQLRDQVNITPSVHSTGEFPQLLHHGVNVGSLPHNESYLLAQQNGSPANVLEASMRSITPQINGKSSSDDFEQLIRSMSQGRPVETIELIKPLSGGLGFSVVGLKSENRGELGIFVQEIQEGSVAHRDGKLKEADQILAINGQALDQTITHQQAISILQKAKDNVQLVVARGNFPQLISPVVSRSPSAASTVSAHSNPVHWQHVETIELVNDGSGLGFGIVGGKSTGVIVKTILPGGVADQHGRLCSGDHILKIGDTDLTGMSSEQVAQVLRQCGNRVKLVIARGPVEEPPPPAVPPGTPVPITTTEKQTDVSVDSCEEGEKFNVELTKNTQGLGITIAGYIGDKTSEPSGIFVKSITKGSAVEQDGRIHVGDQIIVVDGTNLQGFTNQQAVDVLRHTGQTVRLTLIRRGLKQENYIQPQEDFSAAVERDLMLQTVDSSTAKDSSEPEQGSPSQPCSGSAVNIREDIKQQETDFQLSATEEEAMKAKWQRIMGSNYEIVVAVVSKFSESSGLGISLEATVGHHFIRSILPEGPVGRSGKLFSGDELLEVNEISLLGENHKDVVNILKELPIKVTMVCCRPVASSVSHTEVLENLSLSEVQLAEKAHIDLGFIGSSNTEETALEISTAQTMEEVQNSSFTMWEAEVQHTELEKGSMGLGFSILDYQDPVDPSKTIILIRSLVPGGVAEQDGRLSPGDRLMFVNDISLENGSLEEAVQALKGAPVGAVKIGVAKPLPLSPEEGCVSAKEDCFFYTAQSLEEEGPADAALFHAELALVDSSGAGLAVEPSFESQLAPENLTFPTSSPAASDSFCSEDLNFGVPFSASTPKIAGKEYLSYADDNDISTESSYSMDLSERGREQSAAEDRSLEATATFSDETFLSEDIFDIKHDKEVVTESSLILPVNKDFTISKMIKNIFEKTITIAKGNSSLGMTVSSDKDGTGMIVRSVIHGGSISRDGRINVGDCILSINEESSTNLTNAQARAMLRRHSLSGPEISITYVLAENLPKYRASLEQQSEETMSVISSSQSASIREIPELPEREEGEGEESELQNAAFSNWNQPRKVELWREPGKSLGISIVGGRGMGSRLSSGEVMRGIFIKHILEDSPAGKNGTLKTGDRIVEVDGIDLRDASHEQAVEAIRKAGNPVVFMVQSIISRSRAFGQSTSEPEKTSFCNLPLPPPSTFLGINSDVAQSSSSQVTEDVEKENEFGYSWKKITQRYGSLPGELHMIELEKGRTGLGLSLAGNKDRSRMSVFVVGIDPNGAAGKDGRLQIADELLEINGQILYGRTHQNASSIIKCAPSKVKIIFIRNKDAVNQMAVCPAKSIEALPCASETLQNQEIDTTADGGVSPDFSSYKNIQYVELPKDEGGLGIAISEEDTDSGVVIKSLTDHGAAAKDGRIKIGTQILAVDDEIVVGYPVEKFINLLKSSKNMVKLTVNSAESDSQTIAPVLSSAAPGERRNIHPPTAICSSNSPEPEPVKNTSRSSTPATLASDPATCPIIPGCETTIDISKGQTGLGLSIVGGADTLLGAIIIHEVYEEGAASKDGRLWAGDQILEVNGIDLRSATHDEAINVLRQTPQKVRLTVYRDEAQYKEEDMYDVVVIELQKKPGKGLGLSIVGKRNDTGVFVSDIVKGGIADTDGRLMQGDQILTVNGEDVRNTNQEAVAALLKCSLGTVRLEVGRIKAGPFHSERRTSQSSQVSEGSGSLSSFSISASASSTPEVFESGLKRNTASSEIQGLRTVEIKKGPADSLGVSIAGGVGSPLGDIPIFIAMMHPNGVAAQTQKLRVGDRIVSICGTSTEGMTHSQAVSILKNASGTIELQVVAGGDVSVITGQQQDPPTSSLSLAGLTSTSIFQDDLGPPQYKTITLERGPDGLGFSIVGGYGSPHGDLPIYVKTVFAKGAAAEDGRLKRGDQIIAVNGQSLEGVTHEEAVAILKRTKGTVTLTVLS", "length": 2006, "header": "tr|A0A8V0YV13-1|A0A8V0YV13_CHICK Computationally mapped isoform of Multiple PDZ domain protein OS=Gallus gallus OX=9031 GN=MPDZ PE=1 SV=1 CANONICAL=A0A8V0YNJ7-1" }, "locus": { "chromosome": "Z", "start_pos": 31490983, "end_pos": 31399485, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010039134.1", "url": "https://www.ensembl.org/id/ENSGALT00010039134.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010022594.1", "url": "https://www.ensembl.org/id/ENSGALP00010022594.1" } ] } }, { "isoform_ac": "A0A8V0YV19-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNJ7/entry#A0A8V0YV19-1", "sequence": { "sequence": "MLETIDTHRALQAVERLQAKLRDRGDIANEEKLNLLKSVLQSPLFNQILNLQTSVQQLRDQVNITPSVHSTGEFPQLLHHGVNVGSLPHNESYLLAQQNGSPANVLEASMRSITPQINGKSSSDDFEQLIRSMSQGRPVETIELIKPLSGGLGFSVVGLKSENRGELGIFVQEIQEGSVAHRDGKLKEADQILAINGQALDQTITHQQAISILQKAKDNVQLVVARGNFPQLISPVVSRSPSAASTVSAHSNPVHWQHVETIELVNDGSGLGFGIVGGKSTGVIVKTILPGGVADQHGRLCSGDHILKIGDTDLTGMSSEQVAQVLRQCGNRVKLVIARGPVEEPPPPAVPPGTPVPITTTEKQTDVSVDSCEEGEKFNVELTKNTQGLGITIAGYIGDKTSEPSGIFVKSITKGSAVEQDGRIHVGDQIIVVDGTNLQGFTNQQAVDVLRHTGQTVRLTLIRRGLKQENYIQPQEDFSAAVERDLMLQTVDSSTAKDSSEPEQGSPSQPCSGSAVNIREDIKQQETDFQLSATEEEAMKAKWQRIMGSNYEIVVAVVSKFSESSGLGISLEATVGHHFIRSILPEGPVGRSGKLFSGDELLEVNEISLLGENHKDVVNILKELPIKVTMVCCRPVASSVSHTEVLENLSLSEVQLAEKAHIDLGFIGSSNTEETALEISTAQTMEEVQNSSFTMWEAEVQHTELEKGSMGLGFSILDYQDPVDPSKTIILIRSLVPGGVAEQDGRLSPGDRLMFVNDISLENGSLEEAVQALKGAPVGAVKIGVAKPLPLSPEEGCVSAKEDCFFYTAQSLEEEGPADAALFHAELALVDSSGAGLAVEPSFESQLAPENLTFPTSSPAASDSFCSEDLNFGVPFSASTPKIAGKEYLSYADDNDISTESSYSMDLSERGREQSAAEDRSLEATATFSDETFLSEDIFDIKHDKEVVTESSLILPVNKDFTISKMIKNIFEKTITIAKGNSSLGMTVSSDKDGTGMIVRSVIHGGSISRDGRINVGDCILSINEESSTNLTNAQARAMLRRHSLSGPEIRSSPAPSDDQALFYVITYVLAENLPKYRASLEQQSEETMSVISSSQSASIREIPELPEREEGEGEESELQNAAFSNWNQPRKVELWREPGKSLGISIVGGRGMGSRLSSGEVMRGIFIKHILEDSPAGKNGTLKTGDRIVEAFGQSTSEPEKTSFCNLPLPPPSTFLGINSDVAQSSSSQVTEDVEKENEFGYSWKKITQRYGSLPGELHMIELEKGRTGLGLSLAGNKDRSRMSVFVVGIDPNGAAGKDGRLQIADELLEINGQILYGRTHQNASSIIKCAPSKVKIIFIRNKDAVNQMAVCPAKSIEALPCASETLQNQEIDTTADGGVSPDFSSYKNIQYVELPKDEGGLGIAISEEDTDSGVVIKSLTDHGAAAKDGRIKIGTQILAVDDEIVVGYPVEKFINLLKSSKNMVKLTVNSAESDSQTIAPVLSSAAPGERRNIHPPTAICSSNSPEPEPVKNTSRSSTPATLASDPATCPIIPGCETTIDISKGQTGLGLSIVGGADTLLGAIIIHEVYEEGAASKDGRLWAGDQILEVNGIDLRSATHDEAINVLRQTPQKVRLTVYRDEAQYKEEDMYDVVVIELQKKPGKGLGLSIVGKRNDTGVFVSDIVKGGIADTDGRLMQGDQILTVNGEDVRNTNQEAVAALLKCSLGTVRLEVGRIKAGPFHSERRTSQSSQVSEGSGSLSSFSISASASSTPEVFESGLKRNTASSEIQGLRTVEIKKGPADSLGVSIAGGVGSPLGDIPIFIAMMHPNGVAAQTQKLRVGDRIVSICGTSTEGMTHSQAVSILKNASGTIELQVVAGGDVSVITGQQQDPPTSSLSLAGLTSTSIFQDDLGPPQYKTITLERGPDGLGFSIVGGYGSPHGDLPIYVKTVFAKGAAAEDGRLKRGDQIIAVNGQSLEGVTHEEAVAILKRTKGTVTLTVLS", "length": 1983, "header": "tr|A0A8V0YV19-1|A0A8V0YV19_CHICK Computationally mapped isoform of Multiple PDZ domain protein OS=Gallus gallus OX=9031 GN=MPDZ PE=1 SV=1 CANONICAL=A0A8V0YNJ7-1" }, "locus": { "chromosome": "Z", "start_pos": 31490983, "end_pos": 31399485, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010039148.1", "url": "https://www.ensembl.org/id/ENSGALT00010039148.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010022599.1", "url": "https://www.ensembl.org/id/ENSGALP00010022599.1" } ] } }, { "isoform_ac": "A0A8V0YV31-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNJ7/entry#A0A8V0YV31-1", "sequence": { "sequence": "MLETIDTHRALQAVERLQAKLRDRGDIANEEKLNLLKSVLQSPLFNQILNLQTSVQQLRDQGRPVETIELIKPLSGGLGFSVVGLKSENRGELGIFVQEIQEGSVAHRDGKLKEADQILAINGQALDQTITHQQAISILQKAKDNVQLVVARGNFPQLISPVVSRSPSAASTVSAHSNPVHWQHVETIELVNDGSGLGFGIVGGKSTGVIVKTILPGGVADQHGRLCSGDHILKIGDTDLTGMSSEQVAQVLRQCGNRVKLVIARGPVEEPPPPAVPPGTPVPITTTEKQTDVSVDSCEEGEKFNVELTKNTQGLGITIAGYIGDKTSEPSGIFVKSITKGSAVEQDGRIHVGDQIIVVDGTNLQGFTNQQAVDVLRHTGQTVRLTLIRRGLKQENYIQPQEDFSAAVERDLMLQTVDSSTAKDSSEPEQGSPSQPCSGSAVNIREDIKQQETDFQLSATEEEAMKAKWQRIMGSNYEIVVAVVSKFSESSGLGISLEATVGHHFIRSILPEGPVGRSGKLFSGDELLEVNEISLLGENHKDVVNILKELPIKVTMVCCRPVASSVSHTEVLENLSLSEVQLAEKAHIDLGFIGSSNTEETALEISTAQTMEEVQNSSFTMWEAEVQHTELEKGSMGLGFSILDYQDPVDPSKTIILIRSLVPGGVAEQDGRLSPGDRLMFVNDISLENGSLEEAVQALKGAPVGAVKIGVAKPLPVDSSGAGLAVEPSFESQLAPENLTFPTSSPAASDSFCSEDLNFGVPFSASTPKIAGKEYLSYADDNDISTESSYSMDLSERGREQSAAEDRSLEATATFSDETFLSEDIFDIKHDKEVVTESSLILPVNKDFTISKMIKNIFEKTITIAKGNSSLGMTVSSDKDGTGMIVRSVIHGGSISRDGRINVGDCILSINEESSTNLTNAQARAMLRRHSLSGPEIRSSPAPSDDQALFYVITYVLAENLPKYRASLEQQSEETMSVISSSQSASIREIPELPEREEGEGEESELQNAAFSNWNQPRKVELWREPGKSLGISIVGGRGMGSRLSSGEVMRGIFIKHILEDSPAGKNGTLKTGDRIVEVDGIDLRDASHEQAVEAIRKAGNPVVFMVQSIISRSRAFGQSTSEPEKTSFCNLPLPPPSTFLGINSDVAQSSSSQVTEDVEKENEFGYSWKKITQRYGSLPGELHMIELEKGRTGLGLSLAGNKDRSRMSVFVVGIDPNGAAGKDGRLQIADELLEINGQILYGRTHQNASSIIKCAPSKVKIIFIRNKDAVNQMAVCPAKSIEALPCASETLQNQEIDTTADGGVSPDFSSYKNIQYVELPKDEGGLGIAISEEDTDSGVVIKSLTDHGAAAKDGRIKIGTQILAVDDEIVVGYPVEKFINLLKSSKNMVKLTVNSAESDSQTIAPVLSSAAPGERRNIHPPTAICSSNSPEPEPVKNTSRSSTPATLASDPATCPIIPGCETTIDISKGQTGLGLSIVGGADTLLGAIIIHEVYEEGAASKDGRLWAGDQILEVNGIDLRSATHDEAINVLRQTPQKVRLTVYRDEAQYKEEDMYDVVVIELQKKPGKGLGLSIVGKRNDTGVFVSDIVKGGIADTDGRLMQGDQILTVNGEDVRNTNQEAVAALLKCSLGTVRLEVGRIKAGPFHSERRTSQSSQVSEGSGSLSSFSISASASSTPEVFESGLKRNTASSEIQGLRTVEIKKGPADSLGVSIAGGVGSPLGDIPIFIAMMHPNGVAAQTQKLRVGDRIVSICGTSTEGMTHSQAVSILKNASGTIELQVVAGGDVSVITGQQQDPPTSSLSLAGLTSTSIFQDDLGPPQYKTITLERGPDGLGFSIVGGYGSPHGDLPIYVKTVFAKGAAAEDGRLKRGDQIIAVNGQSLEGVTHEEAVAILKRTKGTVTLTVLS", "length": 1907, "header": "tr|A0A8V0YV31-1|A0A8V0YV31_CHICK Computationally mapped isoform of Multiple PDZ domain protein OS=Gallus gallus OX=9031 GN=MPDZ PE=1 SV=1 CANONICAL=A0A8V0YNJ7-1" }, "locus": { "chromosome": "Z", "start_pos": 31490983, "end_pos": 31399485, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010039166.1", "url": "https://www.ensembl.org/id/ENSGALT00010039166.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010022609.1", "url": "https://www.ensembl.org/id/ENSGALP00010022609.1" } ] } }, { "isoform_ac": "A0A8V0YX06-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNJ7/entry#A0A8V0YX06-1", "sequence": { "sequence": "MLETIDTHRALQAVERLQAKLRDRGDIANEEKLNLLKSVLQSPLFNQILNLQTSVQQLRDQVNITPSVHSTGEFPQLLHHGVNVGSLPHNESYLLAQQNGSPANVLEASMRSITPQINGKSSSDDFEQLIRSMSQGRPVETIELIKPLSGGLGFSVVGLKSENRGELGIFVQEIQEGSVAHRDGKLKEADQILAINGQALDQTITHQQAISILQKAKDNVQLVVARGNFPQLISPVVSRSPSAASTVSAHSNPVHWQHVETIELVNDGSGLGFGIVGGKSTGVIVKTILPGGVADQHGRLCSGDHILKIGDTDLTGMSSEQVAQVLRQCGNRVKLVIARGPVEEPPPPAVPPGTPVPITTTEKQTDVSVDSCEEGEKFNVELTKNTQGLGITIAGYIGDKTSEPSGIFVKSITKGSAVEQDGRIHVGDQIIVVDGTNLQGFTNQQAVDVLRHTGQTVRLTLIRRGLKQENYIQPQEDFSAAVERDLMLQTVDSSTAKDSSEPEQGSPSQPCSGSAVNIREDIKQQETDFQLSATEEEAMKAKWQRIMGSNYEIVVAVVSKFSESSGLGISLEATVGHHFIRSILPEGPVGRSGKLFSGDELLEVNEISLLGENHKDVVNILKELPIKVTMVCCRPVASSVSHTEVLENLSLSEVQLAEKAHIDLGFIGSSNTEETALEISTAQTMEEVQNSSFTMWEAEVQHTELEKGSMGLGFSILDYQDPVDPSKTIILIRSLVPGGVAEQDGRLSPGDRLMFVNDISLENGSLEEAVQALKGAPVGAVKIGVAKPLPLSPEEGCVSAKEDCFFYTAQSLEEEGPADAALFHAELALVDSSGAGLAVEPSFESQLAPENLTFPTSSPAASDSFCSEDLNFGVPFSASTPKIAGKEYLSYADDNDISTESSYSMDLSERGREQSAAEDRSLEATATFSDETFLSEDIFDIKHDKEVVTESSLILPVNKDFTISKMIKNIFEKTITIAKGNSSLGMTVSSDKDGTGMIVRSVIHGGSISRDGRINVGDCILSINEESSTNLTNAQARAMLRRHSLSGPEIRSSPAPSDDQALFYVITYVLAENLPKYRASLEQQSEETMSVISSSQSASIREIPELPEREEGEGEESELQNAAFSNWNQPRKVELWREPGKSLGISIVGGRGMGSRLSSGEVMRGIFIKHILEDSPAGKNGTLKTGDRIVEVDGIDLRDASHEQAVEAIRKAGNPVVFMVQSIISRSRPESLYSPSSASALCEQKTTNPFYHQSSKEVSNPIRVTFRCSPTNPFAPTPFKAFGQSTSEPEKTSFCNLPLPPPSTFLGINSDVAQSSSSQVTEDVEKENEFGYSWKKITQRYGSLPGELHMIELEKGRTGLGLSLAGNKDRSRMSVFVVGIDPNGAAGKDGRLQIADELLEINGQILYGRTHQNASSIIKCAPSKVKIIFIRNKDAVNQMAVCPAKSIEALPCASETLQNQEIDTTADGGVSPDFSSYKNIQYVELPKDEGGLGIAISEEDTDSGVVIKSLTDHGAAAKDGRIKIGTQILAVDDEIVVGYPVEKFINLLKSSKNMVKLTVNSAESDSQTIAPVLSSAAPGERRNIHPPTAICSSNSPEPEPVKNTSRSSTPATLASDPATCPIIPGCETTIDISKGQTGLGLSIVGGADTLLGAIIIHEVYEEGAASKDGRLWAGDQILEVNGIDLRSATHDEAINVLRQTPQKVRLTVYRDEAQYKEEDMYDVVVIELQKKPGKGLGLSIVGKRNDTGVFVSDIVKGGIADTDGRLMQGDQILTVNGEDVRNTNQEAVAALLKCSLGTVRLEVGRIKAGPFHSERRTSQSSQVSEGSGSLSSFSISASASSTPEVFESGLKRNTASSEIQGLRTVEIKKGPADSLGVSIAGGVGSPLGDIPIFIAMMHPNGVAAQTQKLRVGDRIVSICGTSTEGMTHSQAVSILKNASGTIELQVVAGGDVSVITGQQQDPPTSSLSLAGLTSTSIFQDDLGPPQYKTITLERGPDGLGFSIVGGYGSPHGDLPIYVKTVFAKGAAAEDGRLKRGDQIIAVNGQSLEGVTHEEAVAILKRTKGTVTLTVLS", "length": 2072, "header": "tr|A0A8V0YX06-1|A0A8V0YX06_CHICK Computationally mapped isoform of Multiple PDZ domain protein OS=Gallus gallus OX=9031 GN=MPDZ PE=1 SV=1 CANONICAL=A0A8V0YNJ7-1" }, "locus": { "chromosome": "Z", "start_pos": 31490983, "end_pos": 31399485, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010039108.1", "url": "https://www.ensembl.org/id/ENSGALT00010039108.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010022585.1", "url": "https://www.ensembl.org/id/ENSGALP00010022585.1" } ] } }, { "isoform_ac": "A0A8V0YX16-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNJ7/entry#A0A8V0YX16-1", "sequence": { "sequence": "MLETIDTHRALQAVERLQAKLRDRGDIANEEKLNLLKSVLQSPLFNQILNLQTSVQQLRDQVNITPSVHSTGEFPQLLHHGVNVGSLPHNESYLLAQQNGSPANVLEASMRSITPQINGKSSSDDFEQLIRSMSQGRPVETIELIKPLSGGLGFSVVGLKSENRGELGIFVQEIQEGSVAHRDGKLKEADQILAINGQALDQTITHQQAISILQKAKDNVQLVVARGNFPQLISPVVSRSPSAASTVSAHSNPVHWQHVETIELVNDGSGLGFGIVGGKSTGVIVKTILPGGVADQHGRLCSGDHILKIGDTDLTGMSSEQVAQVLRQCGNRVKLVIARGPVEEPPPPAVPPGTPVPITTTEKQTDVSVDSCEEGEKFNVELTKNTQGLGITIAGYIGDKTSEPSGIFVKSITKGSAVEQDGRIHVGDQIIVVDGTNLQGFTNQQAVDVLRHTGQTVRLTLIRRGLKQENYIQPQEDFSAAVERDLMLQTVDSSTAKDSSEPEQGSPSQPCSGSAVNIREDIKQQETDFQLSATEEEAMKAKWQRIMGSNYEIVVAVVSKFSESSGLGISLEATVGHHFIRSILPEGPVGRSGKLFSGDELLEVNEISLLGENHKDVVNILKELPIKVTMVCCRPVASSVSHTEVLENLSLSEVQLAEKAHIDLGFIGSSNTEETALEISTAQTMEEVQNSSFTMWEAEVQHTELEKGSMGLGFSILDYQDPVDPSKTIILIRSLVPGGVAEQDGRLSPGDRLMFVNDISLENGSLEEAVQALKGAPVGAVKIGVAKPLPLSPEEGCVSAKEDCFFYTAQSLEEEGPADAALFHAELALVDSSGAGLAVEPSFESQLAPENLTFPTSSPAASDSFCSEDLNFGVPFSASTPKIAGKEYLSYADDNDISTESSYSMDLSERGREQSAAEDRSLEATATFSDETFLSEDIFDIKHDKEVVTESSLILPVNKDFTISKMIKNIFEKTITIAKGNSSLGMTVSSDKDGTGMIVRSVIHGGSISRDGRINVGDCILSINEESSTNLTNAQARAMLRRHSLSGPEISITYVLAENLPKYRASLEQQSEETMSVISSSQSASIREIPELPEREEGEGEESELQNAAFSNWNQPRKVELWREPGKSLGISIVGGRGMGSRLSSGEVMRGIFIKHILEDSPAGKNGTLKTGDRIVEVDGIDLRDASHEQAVEAIRKAGNPVVFMVQSIISRSRAFGQSTSEPEKTSFCNLPLPPPSTFLGINSDVAQSSSSQVTEDVEKENEFGYSWKKITQRYGSLPGELHMIELEKGRTGLGLSLAGNKDRSRMSVFVVGIDPNGAAGKDGRLQIADELLEINGQILYGRTHQNASSIIKCAPSKVKIIFIRNKDAVNQMAVCPAKSIEALPCASETLQNQEIDTTADGGVSPDFSSYKNIQYVELPKDEGGLGIAISEEDTDSGVVIKSLTDHGAAAKDGRIKIGTQILAVDDEIVVGYPVEKFINLLKSSKNMVKLTVNSAESDSQTIAPVLSSAAPGERRNIHPPTAICSSNSPEPEPVKNTSRSSTPATLASDPATCPIIPGCETTIDISKGQTGLGLSIVGGADTLLGAIIIHEVYEEGAASKDGRLWAGDQILEVNGIDLRSATHDEAINVLRQTPQKVRLTVYRDEAQYKEEDMYDVVVIELQKKPGKGLGLSIVGKRNDTGVFVSDIVKGGIADTDGRLMQGDQILTVNGEDVRNTNQEAVAALLKCSLGTVRLEVGRIKAGPFHSERRTSQSSQVSEGSGSLSSFSISASASSTPEVFESGLKRNTGKISLVLPLGPADSLGVSIAGGVGSPLGDIPIFIAMMHPNGVAAQTQKLRVGDRIVSICGTSTEGMTHSQAVSILKNASGTIELQVVAGGDVSVITGQQQDPPTSSLSLAGLTSTSIFQDDLGPPQYKTITLERGPDGLGFSIVGGYGSPHGDLPIYVKTVFAKGAAAEDGRLKRGDQIIAVNGQSLEGVTHEEAVAILKRTKGTVTLTVLS", "length": 2000, "header": "tr|A0A8V0YX16-1|A0A8V0YX16_CHICK Computationally mapped isoform of Multiple PDZ domain protein OS=Gallus gallus OX=9031 GN=MPDZ PE=1 SV=1 CANONICAL=A0A8V0YNJ7-1" }, "locus": { "chromosome": "Z", "start_pos": 31490983, "end_pos": 31399485, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010039139.1", "url": "https://www.ensembl.org/id/ENSGALT00010039139.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010022595.1", "url": "https://www.ensembl.org/id/ENSGALP00010022595.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:427360", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427360", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "tight junction assembly", "id": "GO:0120192", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120192", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNJ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNJ7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 8, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNJ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNJ7" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNJ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNJ7" } ], "pmid": "" }, { "name": "bicellular tight junction", "id": "GO:0005923", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005923", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNJ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNJ7" } ], "pmid": "" }, { "name": "postsynaptic density", "id": "GO:0014069", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0014069", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNJ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNJ7" } ], "pmid": "" }, { "name": "dendrite", "id": "GO:0030425", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030425", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNJ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNJ7" } ], "pmid": "" }, { "name": "apical part of cell", "id": "GO:0045177", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045177", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNJ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNJ7" } ], "pmid": "" }, { "name": "apical plasma membrane", "id": "GO:0016324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016324", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNJ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNJ7" } ], "pmid": "" }, { "name": "apicolateral plasma membrane", "id": "GO:0016327", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016327", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNJ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNJ7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1030, "end_pos": 1032, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1180, "end_pos": 1182, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1257, "end_pos": 1259, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1447, "end_pos": 1449, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1637, "end_pos": 1639, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1779, "end_pos": 1781, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1971, "end_pos": 1973, "annotation": "n_glycosylation_sequon" }, { "start_pos": 63, "end_pos": 65, "annotation": "n_glycosylation_sequon" }, { "start_pos": 648, "end_pos": 650, "annotation": "n_glycosylation_sequon" }, { "start_pos": 690, "end_pos": 692, "annotation": 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}, { "evidence": [ { "id": "A0A8V0YNJ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNJ7" }, { "id": "PS50106", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50106" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PDZ", "eco_id": "ECO_0000259", "start_pos": 141, "end_pos": 228, "start_aa": "Thr", "end_aa": "Asn", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1030, "end_pos": 1032 }, { "start_pos": 1180, "end_pos": 1182 }, { "start_pos": 1257, "end_pos": 1259 }, { "start_pos": 1447, "end_pos": 1449 }, { "start_pos": 1637, "end_pos": 1639 }, { "start_pos": 1779, "end_pos": 1781 }, { "start_pos": 1971, "end_pos": 1973 }, { "start_pos": 63, "end_pos": 65 }, { "start_pos": 648, "end_pos": 650 }, { "start_pos": 690, "end_pos": 692 }, { "start_pos": 763, "end_pos": 765 }, { "start_pos": 851, "end_pos": 853 }, { "start_pos": 90, "end_pos": 92 }, { "start_pos": 981, "end_pos": 983 }, { "start_pos": 99, "end_pos": 101 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": 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{ "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YNK3-1", "uniprot_ac": "A0A8V0YNK3", "uniprot_id": "A0A8V0YNK3_CHICK", "mass": { "chemical_mass": 41945.0, "monoisotopic_mass": 41945.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Reverse transcriptase domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A8V0YNK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNK3/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNK3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNK3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNK3", "locus": {} } ], "crossref": [ { "id": "A0A8V0YNK3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YNK3", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR000477", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000477", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR33332", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR33332", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00078", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00078", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YNK3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNK3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YNK3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNK3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLIMYLGCYTLIVPSEKRNDCSHTRKNCLQKLAVRGLGRYTLGWVSNWLKGRAQRVVVNEVKSSWRPVTSGVPQGSVLGPVLFNIFIDDLDEGIECTLSKFADDTKLAGSVNLPDGSEALQRDLDRLDSWAEAHGMGFNKTKCRVLHFGHNNPRQRYRLGAEWLEDCVEEMDLGVLIDARLNMSQQCAQVAKKANSILACIRNSVVSRNREVIVPLYSALVRPHLEYCVQFWAPHCKKDIEALERVQRRATKLVRGLEHGPYEERLNELGLFSLEKRRLRGDLIALYNYLKGGCSELGVSLLCRVTSGRTRGNGFKLRQGRFRLDIRKCYFSAWVVRHWNGLPREVVESPSLVVFKVRLDVVLRDMVL", "length": 368, "header": "tr|A0A8V0YNK3-1|A0A8V0YNK3_CHICK Isoform 1 of Reverse transcriptase domain-containing protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0YNK3-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YNK3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNK3/entry#A0A8V0YNK3-1", "sequence": { "sequence": "MLIMYLGCYTLIVPSEKRNDCSHTRKNCLQKLAVRGLGRYTLGWVSNWLKGRAQRVVVNEVKSSWRPVTSGVPQGSVLGPVLFNIFIDDLDEGIECTLSKFADDTKLAGSVNLPDGSEALQRDLDRLDSWAEAHGMGFNKTKCRVLHFGHNNPRQRYRLGAEWLEDCVEEMDLGVLIDARLNMSQQCAQVAKKANSILACIRNSVVSRNREVIVPLYSALVRPHLEYCVQFWAPHCKKDIEALERVQRRATKLVRGLEHGPYEERLNELGLFSLEKRRLRGDLIALYNYLKGGCSELGVSLLCRVTSGRTRGNGFKLRQGRFRLDIRKCYFSAWVVRHWNGLPREVVESPSLVVFKVRLDVVLRDMVL", "length": 368, "header": "tr|A0A8V0YNK3-1|A0A8V0YNK3_CHICK Isoform 1 of Reverse transcriptase domain-containing protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0YNK3-1" }, "locus": { "chromosome": "W", "start_pos": 6524513, "end_pos": 6467982, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030520.1", "url": "https://www.ensembl.org/id/ENSGALT00010030520.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017700.1", "url": "https://www.ensembl.org/id/ENSGALP00010017700.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 139, "end_pos": 141, "annotation": "n_glycosylation_sequon" }, { "start_pos": 182, "end_pos": 184, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YNK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNK3" }, { "id": "PS50878", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50878" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Reverse transcriptase", "eco_id": "ECO_0000259", "start_pos": 1, "end_pos": 168, "start_aa": "Met", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 139, "end_pos": 141 }, { "start_pos": 182, "end_pos": 184 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YNL9-1", "uniprot_ac": "A0A8V0YNL9", "uniprot_id": "A0A8V0YNL9_CHICK", "mass": { "chemical_mass": 19011.0, "monoisotopic_mass": 19011.0 }, "refseq": { "ac": "XP_025009133", "name": "osteocrin isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025009133" }, "gene_names": [ { "name": "OSTN", "type": "recommended", "evidence": [ { "id": "A0A8V0YNL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNL9" } ] }, { "name": "OSTN", "type": "synonym", "evidence": [ { "id": "XP_025009133", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025009133" } ] } ], "protein_names": [ { "name": "Osteocrin", "type": "synonym", "evidence": [ { "id": "A0A8V0YNL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNL9/entry#names_and_taxonomy" } ] }, { "name": "osteocrin isoform X2", "type": "synonym", "evidence": [ { "id": "XP_025009133", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025009133" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052540.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_025009133.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_025009133", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025009133" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNL9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNL9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "OSTN", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNL9", "locus": { "chromosome": "9", "start_pos": 13410700, "end_pos": 13478234, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010014291", "url": "https://www.ensembl.org/id/ENSGALG00010014291" } ] } } ], "crossref": [ { "id": "A0A8V0YNL9", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YNL9", "database": "AlphaFoldDB", "categories": [] }, { "id": "424907", "url": "https://www.ncbi.nlm.nih.gov/gene/424907", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR021088", "url": "https://www.ebi.ac.uk/interpro/entry/IPR021088", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PMDRIGG", "url": "https://omabrowser.org/oma/group/PMDRIGG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YNL2", "url": "https://www.orthodb.org/?gene=A0A8V0YNL2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YNL9", "url": "https://www.orthodb.org/?gene=A0A8V0YNL9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YNM8", "url": "https://www.orthodb.org/?gene=A0A8V0YNM8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YQA7", "url": "https://www.orthodb.org/?gene=A0A8V0YQA7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YVG1", "url": "https://www.orthodb.org/?gene=A0A8V0YVG1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YVI3", "url": "https://www.orthodb.org/?gene=A0A8V0YVI3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR35353", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR35353", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR35353:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR35353:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF11037", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11037", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_025009133", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025009133", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YNL2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNL2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YNL2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNL2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YNL9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNL9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YNL9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNL9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YNM8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNM8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YNM8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNM8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQA7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQA7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQA7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQA7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YVG1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YVG1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YVG1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YVG1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YVI3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YVI3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YVI3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YVI3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKSSHVLQQASPTQSTFMEIISLLKDRNQPGKRDPSELQQHGMLQFQLVVVHLALVITLLQWHSSSVLLAEAAPEPLEPSAALGMAAHPTASEEKSASSLAAKLLLLDELVSLENEVTETKKKRSFPGFGSPIDRISATSVDAKGKQRKVVDLPKRRFGVPLDRIGVSRLGNTKG", "length": 175, "header": "tr|A0A8V0YNL9-1|A0A8V0YNL9_CHICK Isoform 1 of Osteocrin OS=Gallus gallus OX=9031 GN=OSTN PE=4 SV=1 CANONICAL=A0A8V0YNL9-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YNL2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNL9/entry#A0A8V0YNL2-1", "sequence": { "sequence": "MLLGRSVAHGYLCLQMLQFQLVVVHLALVITLLQWHSSSVLLAEAAPEPLEPSAALGMAAHPTASEEKSASSLAAKLLLLDELVSLENEVTETKKKRSFPGFGSPIDRISATSVDAKGKQRKVVDLPKRRFGVPLDRIGVSRLGNTKGSSVLND", "length": 154, "header": "tr|A0A8V0YNL2-1|A0A8V0YNL9_CHICK Computationally mapped isoform of Osteocrin OS=Gallus gallus OX=9031 GN=OSTN PE=4 SV=1 CANONICAL=A0A8V0YNL9-1" }, "locus": { "chromosome": "9", "start_pos": 13416544, "end_pos": 13411572, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034470.1", "url": "https://www.ensembl.org/id/ENSGALT00010034470.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020249.1", "url": "https://www.ensembl.org/id/ENSGALP00010020249.1" } ] } }, { "isoform_ac": "A0A8V0YNL9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNL9/entry#A0A8V0YNL9-1", "sequence": { "sequence": "MKSSHVLQQASPTQSTFMEIISLLKDRNQPGKRDPSELQQHGMLQFQLVVVHLALVITLLQWHSSSVLLAEAAPEPLEPSAALGMAAHPTASEEKSASSLAAKLLLLDELVSLENEVTETKKKRSFPGFGSPIDRISATSVDAKGKQRKVVDLPKRRFGVPLDRIGVSRLGNTKG", "length": 175, "header": "tr|A0A8V0YNL9-1|A0A8V0YNL9_CHICK Isoform 1 of Osteocrin OS=Gallus gallus OX=9031 GN=OSTN PE=4 SV=1 CANONICAL=A0A8V0YNL9-1" }, "locus": { "chromosome": "9", "start_pos": 13478121, "end_pos": 13411890, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034476.1", "url": "https://www.ensembl.org/id/ENSGALT00010034476.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020254.1", "url": "https://www.ensembl.org/id/ENSGALP00010020254.1" } ] } }, { "isoform_ac": "A0A8V0YNM8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNL9/entry#A0A8V0YNM8-1", "sequence": { "sequence": "MLLGRSMLQFQLVVVHLALVITLLQWHSSSVLLAEAAPEPLEPSAALGMAAHPTASEEKSASSLAAKLLLLDELVSLENEVTETKKKRSFPGFGSPIDRISATSVDAKGKQRKVVDLPKRRFGVPLDRIGVSRLGNTKGSSVLND", "length": 145, "header": "tr|A0A8V0YNM8-1|A0A8V0YNM8_CHICK Computationally mapped isoform of Osteocrin OS=Gallus gallus OX=9031 GN=OSTN PE=4 SV=1 CANONICAL=A0A8V0YNL9-1" }, "locus": { "chromosome": "9", "start_pos": 13416544, "end_pos": 13411572, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034460.1", "url": "https://www.ensembl.org/id/ENSGALT00010034460.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020242.1", "url": "https://www.ensembl.org/id/ENSGALP00010020242.1" } ] } }, { "isoform_ac": "A0A8V0YQA7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNL9/entry#A0A8V0YQA7-1", "sequence": { "sequence": "MLQFQLVVVHLALVITLLQWHSSSVLLAEAAPEPLEPSAALGMAAHPTASEEKSASSLAAKLLLLDELVSLENEVTETKKKRSFPGFGSPIDRISATSVDAKGKQRKVVDLPKRRFGVPLDRIGVSRLGNTKGSSVLND", "length": 139, "header": "tr|A0A8V0YQA7-1|A0A8V0YQA7_CHICK Computationally mapped isoform of Osteocrin OS=Gallus gallus OX=9031 GN=OSTN PE=4 SV=1 CANONICAL=A0A8V0YNL9-1" }, "locus": { "chromosome": "9", "start_pos": 13416125, "end_pos": 13411572, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034414.1", "url": "https://www.ensembl.org/id/ENSGALT00010034414.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020208.1", "url": "https://www.ensembl.org/id/ENSGALP00010020208.1" } ] } }, { "isoform_ac": "A0A8V0YVG1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNL9/entry#A0A8V0YVG1-1", "sequence": { "sequence": "MQWPCKMLQFQLVVVHLALVITLLQWHSSSVLLAEAAPEPLEPSAALGMAAHPTASEEKSASSLAAKLLLLDELVSLENEVTETKKKRSFPGFGSPIDRISATSVDAKGKQRKVVDLPKRRFGVPLDRIGVSRLGNTKG", "length": 139, "header": "tr|A0A8V0YVG1-1|A0A8V0YVG1_CHICK Computationally mapped isoform of Osteocrin OS=Gallus gallus OX=9031 GN=OSTN PE=4 SV=1 CANONICAL=A0A8V0YNL9-1" }, "locus": { "chromosome": "9", "start_pos": 13416322, "end_pos": 13411890, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034451.1", "url": "https://www.ensembl.org/id/ENSGALT00010034451.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020236.1", "url": "https://www.ensembl.org/id/ENSGALP00010020236.1" } ] } }, { "isoform_ac": "A0A8V0YVI3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNL9/entry#A0A8V0YVI3-1", "sequence": { "sequence": "MLLGRSVAHGYLCLQMLQFQLVVVHLALVITLLQWHSSSVLLAEAAPEPLEPSAALGMAAHPTASEEKSASSLAAKLLLLDELVSLENEVTETKKKRSFPGFGSPIDRISATSVDAKGKQRKVVDLPKRRFGVPLDRIGVSRLGNTKG", "length": 148, "header": "tr|A0A8V0YVI3-1|A0A8V0YVI3_CHICK Computationally mapped isoform of Osteocrin OS=Gallus gallus OX=9031 GN=OSTN PE=4 SV=1 CANONICAL=A0A8V0YNL9-1" }, "locus": { "chromosome": "9", "start_pos": 13416544, "end_pos": 13411890, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034480.1", "url": "https://www.ensembl.org/id/ENSGALT00010034480.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020256.1", "url": "https://www.ensembl.org/id/ENSGALP00010020256.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "P61364-1", "protein_name": "Osteocrin", "gene_name": "Ostn", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLDWRLASTHFILAMIVMLWGSGKAFSVDLASQEFGTASLQSPPTAREEKSATELSAKLLRLDDLVSLENDVFETKKKRSFSGFGSPLDRLSAGSVEHRGKQRKAVDHSKKRFGIPMDRIGRNRLSSSRG", "length": 130 }, "evidence": [ { "id": "A0A8V0YNL9", "url": "https://omabrowser.org/oma/group/A0A8V0YNL9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P61365-1", "protein_name": "Osteocrin", "gene_name": "Ostn", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLDWRLASAHFLLAMILMLWGSGKAFSVDLASEASEFGAESLQSPPTTREEKSATELAAKLLLLDDLVSLENDVFETKKKRSFSGFGSPLDRLSAGSVEHRGKQRRVVDHSKKRFGIPMDRIGRNRLSSSRG", "length": 132 }, "evidence": [ { "id": "A0A8V0YNL9", "url": "https://omabrowser.org/oma/group/A0A8V0YNL9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P61366-1", "protein_name": "Osteocrin", "gene_name": "OSTN", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLDWRLASAHFILAVTLTLWSSGKVLSVDVTTTEAFDSGVIDVQSTPTVREEKSATDLTAKLLLLDELVSLENDVIETKKKRSFSGFGSPLDRLSAGSVDHKGKQRKVVDHPKRRFGIPMDRIGRNRLSNSRG", "length": 133 }, "evidence": [ { "id": "A0A8V0YNL9", "url": "https://omabrowser.org/oma/group/A0A8V0YNL9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "signaling receptor binding", "id": "GO:0005102", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005102", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNL9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNL9" } ], "pmid": "" }, { "name": "hormone activity", "id": "GO:0005179", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005179", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNL9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNL9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNL9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNL9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "hormone-mediated signaling pathway", "id": "GO:0009755", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009755", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNL9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNL9" } ], "pmid": "" }, { "name": "negative regulation of dendrite extension", "id": "GO:1903860", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903860", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNL9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNL9" } ], "pmid": "" }, { "name": "bone growth", "id": "GO:0098868", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098868", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNL9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNL9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YNL6-1", "uniprot_ac": "A0A8V0YNL6", "uniprot_id": "A0A8V0YNL6_CHICK", "mass": { "chemical_mass": 145448.0, "monoisotopic_mass": 145448.0 }, "refseq": {}, "gene_names": [ { "name": "ULK4", "type": "recommended", "evidence": [ { "id": "A0A8V0YNL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNL6" } ] } ], "protein_names": [ { "name": "Unc-51 like kinase 4", "type": "synonym", "evidence": [ { "id": "A0A8V0YNL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNL6/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNL6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNL6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ULK4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNL6", "locus": { "chromosome": "2", "start_pos": 43379616, "end_pos": 43599208, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010016286", "url": "https://www.ensembl.org/id/ENSGALG00010016286" } ] } } ], "crossref": [ { "id": "cd14010", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14010", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000719", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000719", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011009", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011009", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045906", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045906", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056981", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056981", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YNL6", "url": "https://www.orthodb.org/?gene=A0A8V0YNL6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YNM1", "url": "https://www.orthodb.org/?gene=A0A8V0YNM1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YV36", "url": "https://www.orthodb.org/?gene=A0A8V0YV36", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46240", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46240", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46240:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46240:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00069", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00069", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23606", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23606", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YNL6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNL6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YNL6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNL6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YNM1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNM1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YNM1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNM1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YV36", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YV36", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YV36-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YV36-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTVVKVYLSKKIPCFQSLTSEASFSMENFILYEEIGRGNKTIVYKGRRKGTINFVAILCTDKCKRAEITNWVRLTHEIRHKNIVTFHEWYETSNHLWLVMELCTGGSLESVIAQDEHLPEDVVREFGVDLITGLHHIHNLGIIFCELTPGKILLEGPGTLKFTNFCLAKADGENLEEFFALVGSEETGGDVVESTPQRHLKNRLRGSPLYTAPEVIKGGDFSKSSDLWSLGCLLYEMFSGRPPFFSENFSELIEKILYEDPLPPRPRDSASQKPSAEFISLLDGLLQKDPQKRLNWTDVLQHPFWKDSLSHCDGDSSDSQGSSNEDLESWNTKGPEDACKNLSSSRADSKLLSNSFKIVENPTELRPKNAVGESNESIFLLSSRPTPRTSTTVEVTDVTIAPIQNSPQKDSSMTRAENVCSSQQDMESALKELIYTESDLIVTPIIDNPKIMKQAPVRFDSKALHIPAYSAEKLSSLKDLDWNDFLHQACSLLDSTEKNPGTARYKLNLLSYLCAVAVHKEVASRLINSQLFPVLIQQLRAATNWDIRAKVARVIGLLALHTSELGENVPVSEAFILLTELIRENFRNSKLKQCLLPALGELLYLVASEEVKKEHPRECLVVPSAAYTVLMRCLREGEDRIVNHLAAKIIENVCTTLSCYAQGFITGEIGPVLWYLFTHSTVDSLKITAVSALCRLTRYSPSAFQSVIEKVGLTAVLNSLLTGICKIQQYMLTMFSAMLSCGIHLQRLMQEKEFVTTIIRLLESPSTFIRAKAFLVLLQVLINSREMLLLSCQARLVMYIERDSRKTTAGKEQQSGNEYLSKCLDLLIHHIVRELPGILGDIINTLTNVSGRKHPSTVQAKQLKMCLPMMPVVLHLVTSQVFRPRIVTEEFLFNYGTLLNFIRSIESGETNLDGAIGPAASEELIKNTLSTFEAITMHPALLTIHHLTVEGCILPPLVSLVHSQNVEWRLFSLRLLSETTSLLLNHKVMAEEKEESLDSNRKLLSLIRDSLLPQYEHILMAPDPVPLYALKLLVALTEHSPASVSLVEENHLFPALFQVILEHQDNILGNTTQTAVALLNNVVTSKSTNMMLLFAEGLAPHVCNLLIETVALYLEADDKSSTKTANALLLSLLDILHCMLMFTTNIVRQTLQAQKSGAGGDTQVAEDLLLINKPLTDLISLLIQLLPSEDTEIFENASRCLSLLVQLYGGNSQESMTPENMDSFAEVLKSRQETRHRKVLLRIIKRLVTSNEKRSESLKSDGDALLRALQSLAQPASCHADVAVASLASEILRMVACENPKPTK", "length": 1304, "header": "tr|A0A8V0YNL6-1|A0A8V0YNL6_CHICK Isoform 1 of Unc-51 like kinase 4 OS=Gallus gallus OX=9031 GN=ULK4 PE=1 SV=1 CANONICAL=A0A8V0YNL6-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YNL6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNL6/entry#A0A8V0YNL6-1", "sequence": { "sequence": "MTVVKVYLSKKIPCFQSLTSEASFSMENFILYEEIGRGNKTIVYKGRRKGTINFVAILCTDKCKRAEITNWVRLTHEIRHKNIVTFHEWYETSNHLWLVMELCTGGSLESVIAQDEHLPEDVVREFGVDLITGLHHIHNLGIIFCELTPGKILLEGPGTLKFTNFCLAKADGENLEEFFALVGSEETGGDVVESTPQRHLKNRLRGSPLYTAPEVIKGGDFSKSSDLWSLGCLLYEMFSGRPPFFSENFSELIEKILYEDPLPPRPRDSASQKPSAEFISLLDGLLQKDPQKRLNWTDVLQHPFWKDSLSHCDGDSSDSQGSSNEDLESWNTKGPEDACKNLSSSRADSKLLSNSFKIVENPTELRPKNAVGESNESIFLLSSRPTPRTSTTVEVTDVTIAPIQNSPQKDSSMTRAENVCSSQQDMESALKELIYTESDLIVTPIIDNPKIMKQAPVRFDSKALHIPAYSAEKLSSLKDLDWNDFLHQACSLLDSTEKNPGTARYKLNLLSYLCAVAVHKEVASRLINSQLFPVLIQQLRAATNWDIRAKVARVIGLLALHTSELGENVPVSEAFILLTELIRENFRNSKLKQCLLPALGELLYLVASEEVKKEHPRECLVVPSAAYTVLMRCLREGEDRIVNHLAAKIIENVCTTLSCYAQGFITGEIGPVLWYLFTHSTVDSLKITAVSALCRLTRYSPSAFQSVIEKVGLTAVLNSLLTGICKIQQYMLTMFSAMLSCGIHLQRLMQEKEFVTTIIRLLESPSTFIRAKAFLVLLQVLINSREMLLLSCQARLVMYIERDSRKTTAGKEQQSGNEYLSKCLDLLIHHIVRELPGILGDIINTLTNVSGRKHPSTVQAKQLKMCLPMMPVVLHLVTSQVFRPRIVTEEFLFNYGTLLNFIRSIESGETNLDGAIGPAASEELIKNTLSTFEAITMHPALLTIHHLTVEGCILPPLVSLVHSQNVEWRLFSLRLLSETTSLLLNHKVMAEEKEESLDSNRKLLSLIRDSLLPQYEHILMAPDPVPLYALKLLVALTEHSPASVSLVEENHLFPALFQVILEHQDNILGNTTQTAVALLNNVVTSKSTNMMLLFAEGLAPHVCNLLIETVALYLEADDKSSTKTANALLLSLLDILHCMLMFTTNIVRQTLQAQKSGAGGDTQVAEDLLLINKPLTDLISLLIQLLPSEDTEIFENASRCLSLLVQLYGGNSQESMTPENMDSFAEVLKSRQETRHRKVLLRIIKRLVTSNEKRSESLKSDGDALLRALQSLAQPASCHADVAVASLASEILRMVACENPKPTK", "length": 1304, "header": "tr|A0A8V0YNL6-1|A0A8V0YNL6_CHICK Isoform 1 of Unc-51 like kinase 4 OS=Gallus gallus OX=9031 GN=ULK4 PE=1 SV=1 CANONICAL=A0A8V0YNL6-1" }, "locus": { "chromosome": "2", "start_pos": 43598803, "end_pos": 43379889, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010039151.1", "url": "https://www.ensembl.org/id/ENSGALT00010039151.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010022602.1", "url": "https://www.ensembl.org/id/ENSGALP00010022602.1" } ] } }, { "isoform_ac": "A0A8V0YNM1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNL6/entry#A0A8V0YNM1-1", "sequence": { "sequence": "MTVVKVYLSKKIPCFQSLTSEASFSMENFILYEEIGRGNKTIVYKGRRKGTINFVAILCTDKCKRAEITNWVRLTHEIRHKNIVTFHEWYETSNHLWLVMELCTGGSLESVIAQDEHLPEDVVREFGVDLITGLHHIHNLGIIFCELTPGKILLEGPGTLKFTNFCLAKADGENLEEFFALVGSEETGGDVVESTPQRHLKNRLRGSPLYTAPEVIKGGDFSKSSDLWSLGCLLYEMFSGRPPFFSENFSELIEKILYEDPLPPRPRDSASQKPSAEFISLLDGLLQKDPQKRLNWTDVLQHPFWKDSLSHCDGDSSDSQGSSNEDLESWNTKGPEDACKNLSSSRADSKLLSNSFKIVENPTELRPKNAVGESNESIFLLSSRPTPRTSTTVEVTDVTIAPIQNSPQKDSSMTRAENVCSSQQDMESALKELIYTESDLIVTPIIDNPKIMKQAPVRFDSKALHIPAYSAEKLSSLKDLDWNDFLHQACSLLDSTEKNPGTARYKLNLLSYLCAVAVHKEVASRLINSQLFPVLIQQLRAATNWDIRAKVARVIGLLALHTSELGENVPVSEEVKKEHPRECLVVPSAAYTVLMRCLREGEDRIVNHLAAKIIENVCTTLSCYAQGFITGEIGPVLWYLFTHSTVDSLKITAVSALCRLTRYSPSAFQSVIEKVGLTAVLNSLLTGICKIQQYMLTMFSAMLSCGIHLQRLMQEKEFVTTIIRLLESPSTFIRAKAFLVLLQVLINSREMLLLSCQARLVMYIERDSRKTTAGKEQQSGNEYLSKCLDLLIHHIVRELPGILGDIINTLTNVSGRKHPSTVQAKQLKMCLPMMPVVLHLVTSQVFRPRIVTEEFLFNYGTLLNFIRSIESGETNLDGAIGPAASEELIKNTLSTFEAITMHPALLTIHHLTVEGCILPPLVSLVHSQNVEWRLFSLRLLSETTSLLLNHKVMAEEKEESLDSNRKLLSLIRDSLLPQYEHILMAPDPVPLYALKLLVALTEHSPASVSLVEENHLFPALFQVILEHQDNILGNTTQTAVALLNNVVTSKSTNMMLLFAEGLAPHVCNLLIETVALYLEADDKSSTKTANALLLSLLDILHCMLMFTTNIVRQTLQAQKSGAGGDTQVAEDLLLINKPLTDLISLLIQLLPSEDTEIFENASRCLSLLVQLYGGNSQESMTPENMDSFAEVLKSRQETRHRKVLLRIIKRLVTSNEKRSESLKSDGDALLRALQSLAQPASCHADVAVASLASEILRMVACENPKPTK", "length": 1268, "header": "tr|A0A8V0YNM1-1|A0A8V0YNM1_CHICK Computationally mapped isoform of Unc-51 like kinase 4 OS=Gallus gallus OX=9031 GN=ULK4 PE=1 SV=1 CANONICAL=A0A8V0YNL6-1" }, "locus": { "chromosome": "2", "start_pos": 43598803, "end_pos": 43379889, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010039163.1", "url": "https://www.ensembl.org/id/ENSGALT00010039163.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010022607.1", "url": "https://www.ensembl.org/id/ENSGALP00010022607.1" } ] } }, { "isoform_ac": "A0A8V0YV36-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNL6/entry#A0A8V0YV36-1", "sequence": { "sequence": "MAARWRAVSFLQARPLSPRSRPVAFLPDRTSQVYLSKKIPCFQSLTSEASFSMENFILYEEIGRGNKTIVYKGRRKGTINFVAILCTDKCKRAEITNWVRLTHEIRHKNIVTFHEWYETSNHLWLVMELCTGGSLESVIAQDEHLPEDVVREFGVDLITGLHHIHNLGIIFCELTPGKILLEGPGTLKFTNFCLAKADGENLEEFFALVGSEETGGDVVESTPQRHLKNRLRGSPLYTAPEVIKGGDFSKSSDLWSLGCLLYEMFSGRPPFFSENFSELIEKILYEDPLPPRPRDSASQKPSAEFISLLDGLLQKDPQKRLNWTDVLQHPFWKDSLSHCDGDSSDSQGSSNEDLESWNTKGPEDACKNLSSSRADSKLLSNSFKIVENPTELRPKNAVGESNESIFLLSSRPTPRTSTTVEVTDVTIAPIQNSPQKDSSMTRAENVCSSQQDMESALKELIYTESDLIVTPIIDNPKIMKQAPVRFDSKALHIPAYSAEKLSSLKDLDWNDFLHQACSLLDSTEKNPGTARYKLNLLSYLCAVAVHKEVASRLINSQLFPVLIQQLRAATNWDIRAKVARVIGLLALHTSELGENVPVSEAFILLTELIRENFRNSKLKQCLLPALGELLYLVASEEVKKEHPRECLVVPSAAYTVLMRCLREGEDRIVNHLAAKIIENVCTTLSCYAQGFITGEIGPVLWYLFTHSTVDSLKITAVSALCRLTRYSPSAFQSVIEKVGLTAVLNSLLTGICKIQQYMLTMFSAMLSCGIHLQRLMQEKEFVTTIIRLLESPSTFIRAKAFLVLLQVLINSREMLLLSCQARLVMYIERDSRKTTAGKEQQSGNEYLSKCLDLLIHHIVRELPGILGDIINTLTNVSGRKHPSTVQAKQLKMCLPMMPVVLHLVTSQVFRPRIVTEEFLFNYGTLLNFIRSIESGETNLDGAIGPAASEELIKNTLSTFEAITMHPALLTIHHLTVEGCILPPLVSLVHSQNVEWRLFSLRLLSETTSLLLNHKVMAEEKEESLDSNRKLLSLIRDSLLPQYEHILMAPDPVPLYALKLLVALTEHSPASVSLVEENHLFPALFQVILEHQDNILGNTTQTAVALLNNVVTSKSTNMMLLFAEGLAPHVCNLLIETVALYLEADDKSSTKTANALLLSLLDILHCMLMFTTNIVRQTLQLPSEDTEIFENASRCLSLLVQLYGGNSQESMTPENMDSFAEVLKSRQETRHRKVLLRIIKRLVTSNEKRSESLKSDGDALLRALQSLAQPASCHADVAVASLASEILRMVACENPKPTK", "length": 1298, "header": "tr|A0A8V0YV36-1|A0A8V0YV36_CHICK Computationally mapped isoform of Unc-51 like kinase 4 OS=Gallus gallus OX=9031 GN=ULK4 PE=1 SV=1 CANONICAL=A0A8V0YNL6-1" }, "locus": { "chromosome": "2", "start_pos": 43599203, "end_pos": 43379889, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010039176.1", "url": "https://www.ensembl.org/id/ENSGALT00010039176.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010022614.1", "url": "https://www.ensembl.org/id/ENSGALP00010022614.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "protein kinase activity", "id": "GO:0004672", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004672", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNL6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNL6" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNL6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNL6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1070, "end_pos": 1072, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1196, "end_pos": 1198, "annotation": "n_glycosylation_sequon" }, { "start_pos": 248, "end_pos": 250, "annotation": "n_glycosylation_sequon" }, { "start_pos": 295, "end_pos": 297, "annotation": "n_glycosylation_sequon" }, { "start_pos": 341, "end_pos": 343, "annotation": "n_glycosylation_sequon" }, { "start_pos": 375, "end_pos": 377, "annotation": "n_glycosylation_sequon" }, { "start_pos": 39, "end_pos": 41, "annotation": "n_glycosylation_sequon" }, { "start_pos": 848, "end_pos": 850, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YNL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNL6" }, { "id": "PS50011", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50011" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Protein kinase", "eco_id": "ECO_0000259", "start_pos": 29, "end_pos": 305, "start_aa": "Phe", "end_aa": "Trp", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1070, "end_pos": 1072 }, { "start_pos": 1196, "end_pos": 1198 }, { "start_pos": 248, "end_pos": 250 }, { "start_pos": 295, "end_pos": 297 }, { "start_pos": 341, "end_pos": 343 }, { "start_pos": 375, "end_pos": 377 }, { "start_pos": 39, "end_pos": 41 }, { "start_pos": 848, "end_pos": 850 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YQF9-1", "uniprot_ac": "A0A8V0YQF9", "uniprot_id": "A0A8V0YQF9_CHICK", "mass": { "chemical_mass": 33664.0, "monoisotopic_mass": 33664.0 }, "refseq": { "ac": "XP_015149247", "name": "putative monooxygenase p33MONOX isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015149247" }, "gene_names": [ { "name": "KIAA1191", "type": "recommended", "evidence": [ { "id": "A0A8V0YQF9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQF9" } ] }, { "name": "KIAA1191", "type": "synonym", "evidence": [ { "id": "XP_015149247", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015149247" } ] }, { "name": "P33MONOX", "type": "synonym", "evidence": [ { "id": "XP_015149247", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015149247" } ] } ], "protein_names": [ { "name": "Putative monooxygenase p33MONOX", "type": "recommended", "evidence": [ { "id": "A0A8V0YQF9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQF9/entry#names_and_taxonomy" } ] }, { "name": "putative monooxygenase p33MONOX isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015149247", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015149247" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052544.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015149247.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015149247", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015149247" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQF9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQF9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "KIAA1191", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQF9", "locus": { "chromosome": "13", "start_pos": 10034421, "end_pos": 10026667, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010014312", "url": "https://www.ensembl.org/id/ENSGALG00010014312" } ] } } ], "crossref": [ { "id": "A0A8V0YQF9", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YQF9", "database": "AlphaFoldDB", "categories": [] }, { "id": "416230", "url": "https://www.ncbi.nlm.nih.gov/gene/416230", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR026759", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026759", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "TIQAYKG", "url": "https://omabrowser.org/oma/group/TIQAYKG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YNN8", "url": "https://www.orthodb.org/?gene=A0A8V0YNN8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YQF9", "url": "https://www.orthodb.org/?gene=A0A8V0YQF9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR28342", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28342", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR28342:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28342:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15302", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15302", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015149247", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015149247", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YNN8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNN8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YNN8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNN8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQF9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQF9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQF9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQF9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSARQPDAPALEQRGGALPGRMSLPLGVPRRAFSYDDALEDTAPMTPPPADLCANVLWKQPVIPERKYQELAKIEEGDANMNAPVITPSSSTESVNKVPVVKAKATHIIMNSLITKQTQESIQCFEQQAGLRDAGYTPHKGLTAEETKYHRVAEAVHKLKMQSGEMTKDDKQTSSAQSTPSSTPHSSPKHKNRGWFSQGSSASITAPDFVAMEAGGDRLPSERWSFFGPKAIQKSTNDPGGFTIQSYKGAQKPSPMELMRAQATRMTEDPVTFKPPKMDIPVTEGRKQSSHSHNIKPRDLNVLTPTGF", "length": 308, "header": "tr|A0A8V0YQF9-1|A0A8V0YQF9_CHICK Isoform 1 of Putative monooxygenase p33MONOX OS=Gallus gallus OX=9031 GN=KIAA1191 PE=3 SV=1 CANONICAL=A0A8V0YQF9-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YNN8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQF9/entry#A0A8V0YNN8-1", "sequence": { "sequence": "MSARQPDAPALEQRGGALPGRMSLEDTAPMTPPPADLCANVLWKQPVIPERKYQELAKIEEGDANMNAPVITPSSSTESVNKVPVVKAKATHIIMNSLITKQTQESIQCFEQQAGLRDAGYTPHKGLTAEETKYHRVAEAVHKLKMQSGEMTKDDKQTSSAQSTPSSTPHSSPKHKNRGWFSQGSSASITAPDFVAMEAGGDRLPSERWSFFGPKAIQKSTNDPGGFTIQSYKGAQKPSPMELMRAQATRMTEDPVTFKPPKMDIPVTEGRKQSSHSHNIKPRDLNVLTPTGF", "length": 293, "header": "tr|A0A8V0YNN8-1|A0A8V0YQF9_CHICK Computationally mapped isoform of Putative monooxygenase p33MONOX OS=Gallus gallus OX=9031 GN=KIAA1191 PE=3 SV=1 CANONICAL=A0A8V0YQF9-1" }, "locus": { "chromosome": "13", "start_pos": 10032849, "end_pos": 10026794, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034474.1", "url": "https://www.ensembl.org/id/ENSGALT00010034474.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020252.1", "url": "https://www.ensembl.org/id/ENSGALP00010020252.1" } ] } }, { "isoform_ac": "A0A8V0YQF9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQF9/entry#A0A8V0YQF9-1", "sequence": { "sequence": "MSARQPDAPALEQRGGALPGRMSLPLGVPRRAFSYDDALEDTAPMTPPPADLCANVLWKQPVIPERKYQELAKIEEGDANMNAPVITPSSSTESVNKVPVVKAKATHIIMNSLITKQTQESIQCFEQQAGLRDAGYTPHKGLTAEETKYHRVAEAVHKLKMQSGEMTKDDKQTSSAQSTPSSTPHSSPKHKNRGWFSQGSSASITAPDFVAMEAGGDRLPSERWSFFGPKAIQKSTNDPGGFTIQSYKGAQKPSPMELMRAQATRMTEDPVTFKPPKMDIPVTEGRKQSSHSHNIKPRDLNVLTPTGF", "length": 308, "header": "tr|A0A8V0YQF9-1|A0A8V0YQF9_CHICK Isoform 1 of Putative monooxygenase p33MONOX OS=Gallus gallus OX=9031 GN=KIAA1191 PE=3 SV=1 CANONICAL=A0A8V0YQF9-1" }, "locus": { "chromosome": "13", "start_pos": 10032849, "end_pos": 10026794, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034482.1", "url": "https://www.ensembl.org/id/ENSGALT00010034482.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020258.1", "url": "https://www.ensembl.org/id/ENSGALP00010020258.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 179, "start_aa": "Thr", "end_pos": 179, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr179", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 46, "start_aa": "Thr", "end_pos": 46, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr46", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A061IAV1-1", "protein_name": "Putative monooxygenase p33MONOX", "gene_name": "Kiaa1191", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MASRQPEVPALAPSGPLGKMSLPIGMCRRAFSYDDALEDPAPMTPPPSDMGSIPWKPVIPERKYQHLDKTEEGAASVSSLAVTPATATDSSDKTPVVKAKATHVIMNSLITKQTQESIQRFEQQAGLRDAGYTPHKGLTTEETKYLRVAEALHKLKLQSGETTREEKPPASAQSTPSSTPHSSPKQKSRGWFPSGSSTALPGPNPHTMDSGSGNDKNSADKWSLFGARPLQRSDSGFAVQAYKGAPKPSPMELMRAQATRGGEDPATFKPPKIDVPVVEGKKPPPRTHNLKPRDLNVLTPTGF", "length": 303 }, "evidence": [ { "id": "A0A8V0YQF9", "url": "https://omabrowser.org/oma/group/A0A8V0YQF9/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A4X1SLI1-1", "protein_name": "Putative monooxygenase p33MONOX", "gene_name": "KIAA1191", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MASRQPEVPALEPSGPLGKMSLPIGMYRRAFSYDDALEDPAPMTPPPSDMGSIPWKPVIPERKYQHLAKVEEGDASASSPAVPLPPATDSADKVPVVKAKATHVIMSSLITKQTQESIQRFEQQAGLRDAGYTPHKGLTTEETNYLRVAEALHKLKLQSGEITREEKQPASTQSTPSSSPHSSPKQKSRGWFTSGSSIALPGPNLSAMDSGSGDKDRSSADKWGLFAPRSLQKSDSGSFATQVYRGAQKPSPMELIRVQATRMAEDPATFQPPKMDIPVIEGKKQLPRTHNLKPRDLNVLTPTGF", "length": 305 }, "evidence": [ { "id": "A0A8V0YQF9", "url": "https://omabrowser.org/oma/group/A0A8V0YQF9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A4QNZ7-1", "protein_name": "Putative monooxygenase p33MONOX", "gene_name": "p33monox", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MVSRPGDLPALEAGPGSSEGLLGGMSIPAGMTRRALSYDDNLERPMSPPPSDINISNLWKRPVIPERKFARLAEEDESEGGVKQSASFESTKPIPVVKAKASSVMNSLIIKQTQESMQKFEKQAGLTDTGYTPHKGLNAEETRYHRLAESMHKLQMQSTDAKEERQPSSNQSTPAGTPQSSPKQKRRGWFNSQGSTASLTGSEMSTSSSSSVDLASAEGPIERWGVFGPRPQVSKSTTDPGTHPDTSGGFALQSYKGAQKPTPMEVMKAQATRLAEDPTNFKAPPKMEIPTMDGKRQVTRPHKLKHRDMNVLTPSGF", "length": 317 }, "evidence": [ { "id": "A0A8V0YQF9", "url": "https://omabrowser.org/oma/group/A0A8V0YQF9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q3T044-1", "protein_name": "Putative monooxygenase p33MONOX", "gene_name": "P33MONOX", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MASRQPEVPALEPSGPLGKMSLPIGMYRRAFSYDDALEDPTPMTPPPSDMGSIPWKPVIPERKYQDLAKVEEGEPSVSPPAPAPPPATDSAEKAPVVKAKATHVIMSSLITKQTQESIQRFEQQAGLRDAGYTPHKGLTTEETKYLRVAEALHKLKLQSGETAREERQPASTQSTPSSSPQASPKQKSRGWFTSGSATALPGPSLSTMDSGSGDKDRSSADKWSLFGPRSLQKSESGGFAIQAYKGAQKPSPMEVMRAQATRRAEEPATFKPPKMDIPVMEGTKQLPRAHSLKPRDLNVLTPTGF", "length": 305 }, "evidence": [ { "id": "A0A8V0YQF9", "url": "https://omabrowser.org/oma/group/A0A8V0YQF9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q5U2R6-1", "protein_name": "Putative monooxygenase p33MONOX", "gene_name": "P33monox", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASRQPEVPPALAPSGPLSKMSLPIGMCRRAFSYDDALEDPAPMTPPPSDMGSIPWKPVIPERKYQHLDKTEEGAASVSSLAVTPSTATDSSDKAPVVKAKATHIIMNSLITKQTQESIQRFEQQAGLRDAGYTPHKGLTTEETKYLRVAEALHKLKLQSGETTREEKHPASAQSSPSSTPHSSPKQKSRGWFPSGSSTALPAPNPHSMDPGGGNDRNSADKWSLFGPRPLQKSDSGFAIQAYKGAPKPSPMEVMRAQATRAGEDPAVFKPPKMDVPVVEGKKQPPRTHNLKPRDLNVLTPTGF", "length": 304 }, "evidence": [ { "id": "A0A8V0YQF9", "url": "https://omabrowser.org/oma/group/A0A8V0YQF9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q96A73-1", "protein_name": "Putative monooxygenase p33MONOX", "gene_name": "KIAA1191", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MASRQPEVPALEASAPLGKMSLPIGIYRRAVSYDDTLEDPAPMTPPPSDMGSVPWKPVIPERKYQHLAKVEEGEASLPSPAMTLSSAIDSVDKVPVVKAKATHVIMNSLITKQTQESIQHFERQAGLRDAGYTPHKGLTTEETKYLRVAEALHKLKLQSGEVTKEERQPASAQSTPSTTPHSSPKQRPRGWFTSGSSTALPGPNPSTMDSGSGDKDRNLSDKWSLFGPRSLQKYDSGSFATQAYRGAQKPSPLELIRAQANRMAEDPAALKPPKMDIPVMEGKKQPPRAHNLKPRDLNVLTPTGF", "length": 305 }, "evidence": [ { "id": "A0A8V0YQF9", "url": "https://omabrowser.org/oma/group/A0A8V0YQF9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9DBN4-1", "protein_name": "Putative monooxygenase p33MONOX", "gene_name": "P33monox", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASRQPEVPALAPSGPLGKMSLPIGMCRRAFSYDDALEDPAPMTPPPSDMGSIPWKPVIPERKYQHLDKTEEGAASVSSLAVTPSPATDSSDKAPVVKAKATHVIMSSLITKQTQESIQRFEQQAGLRDAGYTPHKGLTTEETKYLRVAEALHKLKLQSGETAKEEKHPASAQSTPSSTPHASPKQKSRGWFPSGSSTALPAPNPHTMDPGSGNDRNSADKWSLFGPRPLQKSDSGFAIQAYKGAPRPSPMEVMRAQATRVGEDPATFKPPKMDVPMVEGKKQPLRTHNLKPRDLNVLTPTGF", "length": 303 }, "evidence": [ { "id": "A0A8V0YQF9", "url": "https://omabrowser.org/oma/group/A0A8V0YQF9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQF9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQF9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "oxidoreductase activity", "id": "GO:0016491", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016491", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQF9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQF9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 46, 179 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YNP1-1", "uniprot_ac": "A0A8V0YNP1", "uniprot_id": "A0A8V0YNP1_CHICK", "mass": { "chemical_mass": 74146.0, "monoisotopic_mass": 74146.0 }, "refseq": { "ac": "XP_040562234", "name": "interferon-induced GTP-binding protein Mx isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040562234" }, "gene_names": [ { "name": "MX1", "type": "recommended", "evidence": [ { "id": "A0A8V0YNP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNP1" } ] }, { "name": "GTPase", "type": "synonym", "evidence": [ { "id": "XP_040562234", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040562234" } ] }, { "name": "MX1", "type": "synonym", "evidence": [ { "id": "XP_040562234", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040562234" } ] }, { "name": "MX", "type": "synonym", "evidence": [ { "id": "XP_040562234", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040562234" } ] } ], "protein_names": [ { "name": "Myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse)", "type": "synonym", "evidence": [ { "id": "A0A8V0YNP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNP1/entry#names_and_taxonomy" } ] }, { "name": "interferon-induced GTP-binding protein Mx isoform X2", "type": "synonym", "evidence": [ { "id": "XP_040562234", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040562234" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040562234", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040562234" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNP1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNP1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MX1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNP1", "locus": { "chromosome": "1", "start_pos": 109022485, "end_pos": 109001642, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013809", "url": "https://www.ensembl.org/id/ENSGALG00010013809" } ] } } ], "crossref": [ { "id": "A0A8V0YNP1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YNP1", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd08771", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd08771", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "395313", "url": "https://www.ncbi.nlm.nih.gov/gene/395313", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000375", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000375", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001401", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001401", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003130", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003130", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020850", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020850", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR022812", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022812", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR030381", "url": "https://www.ebi.ac.uk/interpro/entry/IPR030381", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045063", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045063", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YNP1", "url": "https://www.orthodb.org/?gene=A0A8V0YNP1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11566", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11566", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11566:SF231", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11566:SF231", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00350", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00350", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01031", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01031", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02212", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02212", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_040562234", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040562234", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YNP1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNP1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YNP1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNP1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNNPRSNFSSAFGCPIQIPKQNSNVPPSLPVPVGVFGVPLPLGCSNQMAFCAPELTDRKPEHEQKVSKRLNDREEDKDEAAACSLDNQYDRKIRPCIDLVDSLRKLDIGNDLMLPAIAVIGDRNSGKSSVLEALSGVALPRDKAQDIVAGTNGSITGELISLEIWSPDVPDLTLIDLPGIAREAVGNQPQDNGQQIKTLLKKYIGCKETIIVVVVPCNVDIATTEALKMAQEVDPTGERTLGVLTKPDLVNEGTEETVLKIIQNEVIPLRKGYMIVKCYGQMDFCNELSFTSAIQQEREFFETHKHFSTLLDENKATIPHLANKLTDELVGRIIKTLPAIEKQVHDALQQAKKELQKYTQSTHPTVSDKTIFLVGLIKAFNEDISQTMHGKESWFGNEIRLFPKIRREFRTWGVKLLESSAKVEEIVCSKLPKYEDQYRGREFPDFISYWTFEDIIKEQITKLEEPAVAMLNKVIYMVEEKFLQLANKRFANFQNLNNAAQARIGCISDRQATTAKNCILTQFKMERIIYCQDNIYTDDLKAARAEGISKDTKIKDLAFGCASRQCPSFALEMVSHVKAYFTGASKRLSNQIPLIILSTVLHDFGNYLQTSMLHLLQGKEEINYLLQEDHEAANQQKLLTSRISHLNKAYQYLVDFKSL", "length": 659, "header": "tr|A0A8V0YNP1-1|A0A8V0YNP1_CHICK Isoform 1 of Myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse) OS=Gallus gallus OX=9031 GN=MX1 PE=1 SV=1 CANONICAL=A0A8V0YNP1-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YNP1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNP1/entry#A0A8V0YNP1-1", "sequence": { "sequence": "MNNPRSNFSSAFGCPIQIPKQNSNVPPSLPVPVGVFGVPLPLGCSNQMAFCAPELTDRKPEHEQKVSKRLNDREEDKDEAAACSLDNQYDRKIRPCIDLVDSLRKLDIGNDLMLPAIAVIGDRNSGKSSVLEALSGVALPRDKAQDIVAGTNGSITGELISLEIWSPDVPDLTLIDLPGIAREAVGNQPQDNGQQIKTLLKKYIGCKETIIVVVVPCNVDIATTEALKMAQEVDPTGERTLGVLTKPDLVNEGTEETVLKIIQNEVIPLRKGYMIVKCYGQMDFCNELSFTSAIQQEREFFETHKHFSTLLDENKATIPHLANKLTDELVGRIIKTLPAIEKQVHDALQQAKKELQKYTQSTHPTVSDKTIFLVGLIKAFNEDISQTMHGKESWFGNEIRLFPKIRREFRTWGVKLLESSAKVEEIVCSKLPKYEDQYRGREFPDFISYWTFEDIIKEQITKLEEPAVAMLNKVIYMVEEKFLQLANKRFANFQNLNNAAQARIGCISDRQATTAKNCILTQFKMERIIYCQDNIYTDDLKAARAEGISKDTKIKDLAFGCASRQCPSFALEMVSHVKAYFTGASKRLSNQIPLIILSTVLHDFGNYLQTSMLHLLQGKEEINYLLQEDHEAANQQKLLTSRISHLNKAYQYLVDFKSL", "length": 659, "header": "tr|A0A8V0YNP1-1|A0A8V0YNP1_CHICK Isoform 1 of Myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse) OS=Gallus gallus OX=9031 GN=MX1 PE=1 SV=1 CANONICAL=A0A8V0YNP1-1" }, "locus": { 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"database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd12153", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12153", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "768660", "url": "https://www.ncbi.nlm.nih.gov/gene/768660", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006721", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006721", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036742", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036742", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:768660", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:768660", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QICAQVV", "url": "https://omabrowser.org/oma/group/QICAQVV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q2TXM3", "url": 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This record is derived from a genomic sequence (NC_052539.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_422203.4. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_422203", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_422203" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNR5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNR5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RGS1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNR5", "locus": { "chromosome": "8", "start_pos": 3619511, "end_pos": 3623685, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012788", "url": "https://www.ensembl.org/id/ENSGALG00010012788" } ] } } ], "crossref": [ { "id": "A0A8V0YNR5", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YNR5", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd08715", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd08715", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "424360", "url": "https://www.ncbi.nlm.nih.gov/gene/424360", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR016137", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016137", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036305", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036305", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044926", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044926", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:424360", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424360", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CMVPHIE", "url": "https://omabrowser.org/oma/group/CMVPHIE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YNR5", "url": "https://www.orthodb.org/?gene=A0A8V0YNR5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10845", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10845", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10845:SF34", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10845:SF34", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00615", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00615", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-416476", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-416476", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-418594", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-418594", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_422203", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_422203", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YNR5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNR5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YNR5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNR5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPGLFFSHNNMTELNGKEDCKLAEGKIHKKKQKAFGADLKNYLKCMVPHLESGIKSSTSRNVMLSAEEVTQWSQSLEKLLASQSGQGVFREFLKSEFSEENIEFWLACEDYKKTKADHLHGKAERIYEEFVQSDAIKQINIDHQMREATAKRAQDPTHTSFDEAQRTVYILMERDSYPRFLKSKTYLNLLNQLQTNNAK", "length": 199, "header": "tr|A0A8V0YNR5-1|A0A8V0YNR5_CHICK Isoform 1 of Regulator of G-protein signaling 1 OS=Gallus gallus OX=9031 GN=RGS1 PE=4 SV=1 CANONICAL=A0A8V0YNR5-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YNR5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNR5/entry#A0A8V0YNR5-1", "sequence": { "sequence": "MPGLFFSHNNMTELNGKEDCKLAEGKIHKKKQKAFGADLKNYLKCMVPHLESGIKSSTSRNVMLSAEEVTQWSQSLEKLLASQSGQGVFREFLKSEFSEENIEFWLACEDYKKTKADHLHGKAERIYEEFVQSDAIKQINIDHQMREATAKRAQDPTHTSFDEAQRTVYILMERDSYPRFLKSKTYLNLLNQLQTNNAK", "length": 199, "header": "tr|A0A8V0YNR5-1|A0A8V0YNR5_CHICK Isoform 1 of Regulator of G-protein signaling 1 OS=Gallus gallus OX=9031 GN=RGS1 PE=4 SV=1 CANONICAL=A0A8V0YNR5-1" }, "locus": { "chromosome": "8", "start_pos": 3623655, "end_pos": 3620778, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030655.1", "url": "https://www.ensembl.org/id/ENSGALT00010030655.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017772.1", "url": "https://www.ensembl.org/id/ENSGALP00010017772.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:424360", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424360", "resource": "KEGG Pathway" }, { "id": "R-GGA-416476", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-416476", "resource": "Reactome", "description": "G alpha (q) signalling events" }, { "id": "R-GGA-418594", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-418594", "resource": "Reactome", "description": "G alpha (i) signalling events" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A286ZKX9-1", "protein_name": "Regulator of G-protein signaling 1", "gene_name": "RGS1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRAAAISSPGLDKMPGMFLSAHPKELRGTDHSLLDNKAQKRRPKTFGMDVKAYLRSMIPHLESGMKPAKSKDILSADEVMQWSQSLEKLLANQTGQDVFGNFLKSEFSEENIEFWLACEDYKKTESDLLHRKAEQIYKAFVQSDAAKQINIDFHTREATARKIKAATPTCFDEAQKIIYTLMEKDSYPRFLKSNIYLNLLNDLQANSLK", "length": 209 }, "evidence": [ { "id": "A0A8V0YNR5", "url": "https://omabrowser.org/oma/group/A0A8V0YNR5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8C2LXE3-1", "protein_name": "Regulator of G-protein signaling 1", "gene_name": "Rgs1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MRAAAISMPRLDKMPGMFFSASPKDLKEPSHSLLDDKTQKKRPKTFGMDVKAYLRSMIPHLESGMKSSKSKDILSAEEVMQWSQSLEKLLANQTGQSVFGNFLKSEFSEENIEFWLACEDYKKTESDLLSSKAENIYKAFVHSDAVKQINIDFRTRESTAKKIKAPTPTSFDEAQKVIYTLMEKDSYPRFLKSNIYLNLLNDLQANSLK", "length": 209 }, "evidence": [ { "id": "A0A8V0YNR5", "url": "https://omabrowser.org/oma/group/A0A8V0YNR5/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "F1MUR0-1", "protein_name": "Regulator of G-protein signaling 1", "gene_name": "RGS1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MRAAAISTPRLDKMPGMFLSANPKELKGTDHSLLDDKTQKKRPKTFGMDVKAYLRSMIPHLESGMKSSKSKDLLSADEVKQWSESLEKLLANQTGQDVFGNFLKSEFSEENIEFWLACEDYKKTKSDLLHCKAEKIYKAFVQSDAAKQINIDFRTRESTAKKIKAPTPTSFDEAQKIIYTLMEKDSYPRFLKSNIYLNLLNDLQANSLK", "length": 209 }, "evidence": [ { "id": "A0A8V0YNR5", "url": "https://omabrowser.org/oma/group/A0A8V0YNR5/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P97844-1", "protein_name": "Regulator of G protein signaling 1", "gene_name": "Rgs1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRAAAISMPRLNKMPGMFFSASPKDSKEPSHSLLDDNKQKKRPKTFGMDMKAYLRSMIPHLESGMKSSKSKDILSAEEVMQWSQSLEKLLANQMGQNVFGKFLKSEFSEENIEFWLACEDYKKTETDLLHNKAEHIYKAFVHSDAVKQINIDFHTRESTAKKIKTPTPTCFDEAQKVIYALMEKDSYPRFLKSNIYLNLLNDLQANTLK", "length": 209 }, "evidence": [ { "id": "A0A8V0YNR5", "url": "https://omabrowser.org/oma/group/A0A8V0YNR5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q08116-1", "protein_name": "Regulator of G protein signaling 1", "gene_name": "RGS1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRAAAISTPKLDKMPGMFFSANPKELKGTTHSLLDDKMQKRRPKTFGMDMKAYLRSMIPHLESGMKSSKSKDVLSAAEVMQWSQSLEKLLANQTGQNVFGSFLKSEFSEENIEFWLACEDYKKTESDLLPCKAEEIYKAFVHSDAAKQINIDFRTRESTAKKIKAPTPTCFDEAQKVIYTLMEKDSYPRFLKSDIYLNLLNDLQANSLK", "length": 209 }, "evidence": [ { "id": "A0A8V0YNR5", "url": "https://omabrowser.org/oma/group/A0A8V0YNR5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9JL25-1", "protein_name": "Regulator of G protein signaling 1", "gene_name": "Rgs1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRAAAISMPRLNKMPGMFFSASPKDSKEHSHSLLDDKKQKKRPKTFGMDVKTYLRSMIPHLESGMKSAKSKDILSAEEVMQWSQSLEKLLANQTGQNVFGRFLKSEFSEENIEFWLACEDYKKTETDLLHNKAENIYKAFVHSDAVKQINIDFHTRESTAKKIKTPTPTSFDEAQKVIYSLMEKDSYPRFLKSNIYLNLLNDLQANTLK", "length": 209 }, "evidence": [ { "id": "A0A8V0YNR5", "url": "https://omabrowser.org/oma/group/A0A8V0YNR5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNR5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNR5" } ], "pmid": "" }, { "name": "G-protein alpha-subunit binding", "id": "GO:0001965", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001965", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNR5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNR5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNR5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNR5" } ], "pmid": "" }, { "name": "cytoplasmic side of plasma membrane", "id": "GO:0009898", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009898", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNR5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNR5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "negative regulation of G protein-coupled receptor signaling pathway", "id": "GO:0045744", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045744", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNR5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNR5" } ], "pmid": "" }, { "name": "leukotriene signaling pathway", "id": "GO:0061737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNR5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNR5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 10, "end_pos": 12, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YNR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNR5" }, { "id": "PS50132", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50132" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RGS", "eco_id": "ECO_0000259", "start_pos": 75, "end_pos": 190, "start_aa": "Ser", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 10, "end_pos": 12 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", 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"field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YNR7-1", "uniprot_ac": "A0A8V0YNR7", "uniprot_id": "A0A8V0YNR7_CHICK", "mass": { "chemical_mass": 63394.0, "monoisotopic_mass": 63394.0 }, "refseq": {}, "gene_names": [ { "name": "CTDSPL2", "type": "recommended", "evidence": [ { "id": "A0A8V0YNR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNR7" } ] } ], "protein_names": [ { "name": "CTD small phosphatase like 2", "type": "synonym", "evidence": [ { "id": "A0A8V0YNR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNR7/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNR7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNR7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CTDSPL2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNR7", "locus": { "chromosome": "10", "start_pos": 19796503, "end_pos": 19836797, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010016317", "url": "https://www.ensembl.org/id/ENSGALG00010016317" } ] } } ], "crossref": [ { "id": "A0A8V0YNR7", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YNR7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000008199", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000008199", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd07521", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07521", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "415574", "url": "https://www.ncbi.nlm.nih.gov/gene/415574", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004274", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004274", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011948", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011948", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023214", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023214", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036412", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036412", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050365", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050365", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:415574", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:415574", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "NQAIQVR", "url": "https://omabrowser.org/oma/group/NQAIQVR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PNC2", "url": "https://www.orthodb.org/?gene=A0A1D5PNC2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YNR7", "url": "https://www.orthodb.org/?gene=A0A8V0YNR7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12210", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12210", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03031", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03031", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A1D5PNC2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PNC2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PNC2-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PNC2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YNR7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNR7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YNR7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNR7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKRGGRKHSQTEGKARPAARQAVSPPCNPSTPLLSWLGRSGCCILNISHERLPRVKQTKSFAPDSEGVPKQRLKPQRQRRATVRKDALHVVHMKMRLRTRKASQQSNPIHAQRAQRAKRKHSEVEESLPVGGGKPQKNETGLLSSIKKFIKGSTPKEERENPAKRSRIERDIDNNLITSTPQTGEKPNKQISRVRRKGQVNGEAGSYEMTNQHVKQNGKLEDNPATGSPPRTTLLGTIFSPVFNFFSPANKNGTSGSDSPGQAVEAEEIVKQLDMEQVDEITTSTATSTNGAAYTSQAVQVRSTVNNGLEEVEETNDRDLPPLTAPVSPDSGYSSAHAEATYEEDWEVFDPYYFIKHVPPLTEEQLNRKPALPLKTRSTPEFSLVLDLDETLVHCSLNELEDAALTFPVLFQDVIYQVYVRLRPFFREFLERMSQIYEIILFTASKKVYADKLLNILDPKKQLVRHRLFREHCVCVQGNYIKDLNILGRDLSKTIIIDNSPQAFAYQLSNGIPIESWFMDKNDNELLKLIPFLEKLVELNEDVRPHIRDRFRLHDLLPPD", "length": 560, "header": "tr|A0A8V0YNR7-1|A0A8V0YNR7_CHICK Isoform 1 of CTD small phosphatase like 2 OS=Gallus gallus OX=9031 GN=CTDSPL2 PE=3 SV=1 CANONICAL=A0A8V0YNR7-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PNC2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNR7/entry#A0A1D5PNC2-1", "sequence": { "sequence": "MKMRLRTRKASQQSNPIHAQRAQRAKRKHSEVEESLPVGGGKPQKNETGLLSSIKKFIKGSTPKEERENPAKRSRIERDIDNNLITSTPQTGEKPNKQISRVRRKGQVNGEAGSYEMTNQHVKQNGKLEDNPATGSPPRTTLLGTIFSPVFNFFSPANKNGTSGSDSPGQAVEAEEIVKQLDMEQVDEITTSTATSTNGAAYTSQAVQVRSTVNNGLEEVEETNDRDLPPLTAPVSPDSGYSSAHAEATYEEDWEVFDPYYFIKHVPPLTEEQLNRKPALPLKTRSTPEFSLVLDLDETLVHCSLNELEDAALTFPVLFQDVIYQVYVRLRPFFREFLERMSQIYEIILFTASKKVYADKLLNILDPKKQLVRHRLFREHCVCVQGNYIKDLNILGRDLSKTIIIDNSPQAFAYQLSNGIPIESWFMDKNDNELLKLIPFLEKLVELNEDVRPHIRDRFRLHDLLPPD", "length": 468, "header": "tr|A0A1D5PNC2-1|A0A1D5PNC2_CHICK Computationally mapped isoform of CTD small phosphatase like 2 OS=Gallus gallus OX=9031 GN=CTDSPL2 PE=3 SV=1 CANONICAL=A0A8V0YNR7-1" }, "locus": { "chromosome": "10", "start_pos": 19819970, "end_pos": 19801723, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010039246.1", "url": "https://www.ensembl.org/id/ENSGALT00010039246.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010022650.1", "url": "https://www.ensembl.org/id/ENSGALP00010022650.1" } ] } }, { "isoform_ac": "A0A8V0YNR7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNR7/entry#A0A8V0YNR7-1", "sequence": { "sequence": "MKRGGRKHSQTEGKARPAARQAVSPPCNPSTPLLSWLGRSGCCILNISHERLPRVKQTKSFAPDSEGVPKQRLKPQRQRRATVRKDALHVVHMKMRLRTRKASQQSNPIHAQRAQRAKRKHSEVEESLPVGGGKPQKNETGLLSSIKKFIKGSTPKEERENPAKRSRIERDIDNNLITSTPQTGEKPNKQISRVRRKGQVNGEAGSYEMTNQHVKQNGKLEDNPATGSPPRTTLLGTIFSPVFNFFSPANKNGTSGSDSPGQAVEAEEIVKQLDMEQVDEITTSTATSTNGAAYTSQAVQVRSTVNNGLEEVEETNDRDLPPLTAPVSPDSGYSSAHAEATYEEDWEVFDPYYFIKHVPPLTEEQLNRKPALPLKTRSTPEFSLVLDLDETLVHCSLNELEDAALTFPVLFQDVIYQVYVRLRPFFREFLERMSQIYEIILFTASKKVYADKLLNILDPKKQLVRHRLFREHCVCVQGNYIKDLNILGRDLSKTIIIDNSPQAFAYQLSNGIPIESWFMDKNDNELLKLIPFLEKLVELNEDVRPHIRDRFRLHDLLPPD", "length": 560, "header": "tr|A0A8V0YNR7-1|A0A8V0YNR7_CHICK Isoform 1 of CTD small phosphatase like 2 OS=Gallus gallus OX=9031 GN=CTDSPL2 PE=3 SV=1 CANONICAL=A0A8V0YNR7-1" }, "locus": { "chromosome": "10", "start_pos": 19836598, "end_pos": 19801723, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010039252.1", "url": "https://www.ensembl.org/id/ENSGALT00010039252.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010022654.1", "url": "https://www.ensembl.org/id/ENSGALP00010022654.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:415574", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:415574", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3Q1MZU1-1", "protein_name": "CTD small phosphatase-like protein 2", "gene_name": "CTDSPL2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MRLRTRKASQQSNQIQTQRTARAKRKYSEVDDSLPSGGEKPPKNETGLLSSIKKFIKGSTPKEERENPSKRSRIERDIDNNLITSTPRAGEKPNKQISRVRRKSQVNGEAGSYEMTNQHVKQNGKLEDNPSSGSPPRTTLLGTIFSPVFNFFSPANKNGTSGSDSPGQAVEAEEIVKQLDMEQVDEITTSTTTSANGAAYSNQAVQVRPSINNGLEEAEETVNRDIPPLTAPVTPDSGYSSAHAEATYEEDWEVFDPYYFIKHVPPLTEEQLNRKPALPLKTRSTPEFSLVLDLDETLVHCSLNELEDAALTFPVLFQDVIYQVYVRLRPFFREFLERMSQMYEIILFTASKKVYADKLLNILDPKKQLVRHRLFREHCVCVQGNYIKDLNILGRDLSKTIIIDNSPQAFAYQLSNGIPIESWFMDKNDNELLKLIPFLEKLVELNEDVRPHIRDRFRLHDLLPPD", "length": 466 }, "evidence": [ { "id": "A0A8V0YNR7", "url": "https://omabrowser.org/oma/group/A0A8V0YNR7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A4QNX6-1", "protein_name": "CTD small phosphatase-like protein 2-B", "gene_name": "ctdspl2b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MRLRMRKDSQQPTLARRACPARTKRKSSEVEECTGESKALLSSIKKFIHGSSIKVEQDNPAKTSHLSCELITSTPQRKNDLQRKSIYRARRRTSINGETTNHDTNKPNGKLEVTEEVVSSPPRTTLLGTIFSPVFNFFSPANKNASNSPDQVVEAEEIVKQLEMEQVEEMPTCTATSREPLSVPLYTSAMTSAFRPPPTAHTPEQESENTPHPDLPPLTAPGSPATGGYVDASITVPAEGSYEEEWEVFDPYFFIKHVPPLTEEQLTRKPALPLKTRSTPEFSLVLDLDETLVHCSLNELDDAALTFPVLFQDVIYQVYVRLRPFFREFLERMSQIYEIILFTASKKVYADKLLNILDPRKQLVRHRLFREHCVCVQGNYIKDLNILGRDLSKTIIIDNSPQAFAYQLSNGIPIESWFMDRNDSELLKLVPFLEKLVELNEDVRPHVRERFRLHDLLPPD", "length": 460 }, "evidence": [ { "id": "A0A8V0YNR7", "url": "https://omabrowser.org/oma/group/A0A8V0YNR7/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q05D32-1", "protein_name": "CTD small phosphatase-like protein 2", "gene_name": "CTDSPL2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRLRTRKASQQSNQIQTQRTARAKRKYSEVDDSLPSGGEKPSKNETGLLSSIKKFIKGSTPKEERENPSKRSRIERDIDNNLITSTPRAGEKPNKQISRVRRKSQVNGEAGSYEMTNQHVKQNGKLEDNPSSGSPPRTTLLGTIFSPVFNFFSPANKNGTSGSDSPGQAVEAEEIVKQLDMEQVDEITTSTTTSTNGAAYSNQAVQVRPSLNNGLEEAEETVNRDIPPLTAPVTPDSGYSSAHAEATYEEDWEVFDPYYFIKHVPPLTEEQLNRKPALPLKTRSTPEFSLVLDLDETLVHCSLNELEDAALTFPVLFQDVIYQVYVRLRPFFREFLERMSQMYEIILFTASKKVYADKLLNILDPKKQLVRHRLFREHCVCVQGNYIKDLNILGRDLSKTIIIDNSPQAFAYQLSNGIPIESWFMDKNDNELLKLIPFLEKLVELNEDVRPHIRDRFRLHDLLPPD", "length": 466 }, "evidence": [ { "id": "A0A8V0YNR7", "url": "https://omabrowser.org/oma/group/A0A8V0YNR7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q5XIK8-1", "protein_name": "CTD small phosphatase-like protein 2", "gene_name": "Ctdspl2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKLRTRKASQQSSPIQTQRTARAKRKYSEVDDSLPSGGEKPSKNETGLLSSIKKFIKGSTPKEERENPSKRSRIERDIDNNLITSTPRTGEKPDKQLSRVRRKSPVNGEAGSYEMTNQHIKQNGKLEDNPCSGSPPRTTLLGTIFSPVFNFFSPANKNGTSGSDSPGQAVEAEEIVKQLDMEQVDEITTSTTSANGAAYSNQAVQVRPSLNNGLEEAEETVTRDIPPLTAPVAPESGYSSAHAEATYEEDWEVFDPYYFIKHVPPLTEEQLNRKPALPLKTRSTPEFSLVLDLDETLVHCSLNELEDAALTFPVLFQDVIYQVYVRLRPFFREFLERMSQMYEIILFTASKKVYADKLLNILDPKKQLVRHRLFREHCVCVQGNYIKDLNILGRDLSKTIIIDNSPQAFAYQLSNGIPIESWFMDKNDNELLKLIPFLEKLVELNEDVRPHIRDRFRLHDLLPPD", "length": 465 }, "evidence": [ { "id": "A0A8V0YNR7", "url": "https://omabrowser.org/oma/group/A0A8V0YNR7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8BG15-1", "protein_name": "CTD small phosphatase-like protein 2", "gene_name": "Ctdspl2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKLRTRKASQQSSPIQTQRTARAKRKYSEVDDSLPSGGEKPSKNETGLLSSIKKFIKGSTPKEERENPSKRSRIERDIDNNLITSTPRTGEKPDKQLSRVRRKSPVNGEAGSYEMTNQHIKQNGKLEDNPCSGSPPRTTLLGTIFSPVFNFFSPANKNGTSGSDSPGQAVEAEEIVKQLDMEQVDEITTSTTSANGAAYSNQAVQVRPSLNNGLEEAEETVTRDIPPLTAPVTPESGYSSAHAEATYEEDWEVFDPYYFIKHVPPLTEEQLNRKPALPLKTRSTPEFSLVLDLDETLVHCSLNELEDAALTFPVLFQDVIYQVYVRLRPFFREFLERMSQMYEIILFTASKKVYADKLLNILDPKKQLVRHRLFREHCVCVQGNYIKDLNILGRDLSKTIIIDNSPQAFAYQLSNGIPIESWFMDKNDNELLKLIPFLEKLVELNEDVRPHIRDRFRLHDLLPPD", "length": 465 }, "evidence": [ { "id": "A0A8V0YNR7", "url": "https://omabrowser.org/oma/group/A0A8V0YNR7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNR7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNR7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "phosphoprotein phosphatase activity", "id": "GO:0004721", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004721", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNR7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNR7" } ], "pmid": "" }, { "name": "RNA polymerase II CTD heptapeptide repeat phosphatase activity", "id": "GO:0008420", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008420", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNR7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNR7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "positive regulation of gluconeogenesis", "id": "GO:0045722", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045722", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNR7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNR7" } ], "pmid": "" }, { "name": "growth plate cartilage chondrocyte growth", "id": "GO:0003430", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003430", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNR7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNR7" } ], "pmid": "" }, { "name": "embryonic skeletal system development", "id": "GO:0048706", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048706", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNR7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNR7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 138, "end_pos": 140, "annotation": "n_glycosylation_sequon" }, { "start_pos": 252, "end_pos": 254, "annotation": "n_glycosylation_sequon" }, { "start_pos": 46, "end_pos": 48, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YNR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNR7" }, { "id": "PS50969", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50969" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "FCP1 homology", "eco_id": "ECO_0000259", "start_pos": 377, "end_pos": 536, "start_aa": "Arg", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 138, "end_pos": 140 }, { "start_pos": 252, "end_pos": 254 }, { "start_pos": 46, "end_pos": 48 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YNR9-1", "uniprot_ac": "A0A8V0YNR9", "uniprot_id": "A0A8V0YNR9_CHICK", "mass": { "chemical_mass": 51955.0, "monoisotopic_mass": 51955.0 }, "refseq": {}, "gene_names": [ { "name": "PITX1", "type": "recommended", "evidence": [ { "id": "A0A8V0YNR9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNR9" } ] } ], "protein_names": [ { "name": "Paired like homeodomain 1", "type": "synonym", "evidence": [ { "id": "A0A8V0YNR9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNR9/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNR9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNR9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PITX1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNR9", "locus": { "chromosome": "13", "start_pos": 15224188, "end_pos": 15208672, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012790", "url": "https://www.ensembl.org/id/ENSGALG00010012790" } ] } } ], "crossref": [ { "id": "A0A8V0YNR9", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YNR9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000030237", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000030237", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00086", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00086", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "374201", "url": "https://www.ncbi.nlm.nih.gov/gene/374201", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001356", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001356", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003654", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003654", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009057", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009057", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016233", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016233", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017970", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017970", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:374201", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:374201", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YVDLGGM", "url": "https://omabrowser.org/oma/group/YVDLGGM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5P373", "url": "https://www.orthodb.org/?gene=A0A1D5P373", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YAL7", "url": "https://www.orthodb.org/?gene=A0A8V0YAL7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YGY3", "url": "https://www.orthodb.org/?gene=A0A8V0YGY3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YNR9", "url": "https://www.orthodb.org/?gene=A0A8V0YNR9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45882", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45882", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45882:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45882:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00046", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00046", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF03826", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03826", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A1D5P373", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P373", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5P373-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P373-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YAL7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAL7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YAL7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAL7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YGY3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGY3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YGY3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGY3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YNR9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNR9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YNR9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNR9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRERKNNNKAQMPIEPNALSVLKWHRGRTQGRISAEITAGLNAGPRPQRFVPRTHSDPPAPPGREWGRRPREGSAEGGEDLLSVCSVVQRPGQLWGCCRPCLLCKPLNAGRGHPSCDRPFHRVGVSVEALSPSLLFRRAPRAKGDFSRPSPLTPPHPVSRTQPTILFNLAGIGAAEIPPHRRRLSLRERRTARPGGSGRAERPRSFPRGTEVFASRSGTARSSGPLQPPVPGPASRCVRASQCRSDTAEPELGENRGVRSERKREKRRAEKRGRGRRRPGEEEEATEAADPLHQPAAAGAGSHFPAEPLPRYEHAGGDRRVDEPHRAPRPGVVQEPPSQVEKAGAEPADGPVQERLRAAVQRADAALRRHVRRVPLQQLGHQKPHPGAALHQELHLLQLHEPPLLAVHVLGSQQHLLHEHALRDGPLGRAGHGQLRPQQHQQHQRLLAQLGHVLARLSLWAAGLSLQRVPGHL", "length": 473, "header": "tr|A0A8V0YNR9-1|A0A8V0YNR9_CHICK Isoform 1 of Paired like homeodomain 1 OS=Gallus gallus OX=9031 GN=PITX1 PE=4 SV=1 CANONICAL=A0A8V0YNR9-1" }, "isoforms": [ { "isoform_ac": "A0A1D5P373-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNR9/entry#A0A1D5P373-1", "sequence": { "sequence": "MDSFKGGMNLERLPESLRPQPSHDMASSFHLQRSSEPRDPIENSASESSDTEVPEKERSGEQKNEDGAADDPAKKKKQRRQRTHFTSQQLQELEATFQRNRYPDMSMREEIAVWTNLTEPRVRVWFKNRRAKWRKRERNQQMDLCKNGYVPQFSGLMQPYDDMYAGYPYNNWATKSLTPAPLSTKSFTFFNSMSPLSSQSMFSAPSSISSMNMPSGMGHSAVPGMANSGLNNINNISGSSLNSAMSSPACPYGPPGSPYSVYRDTCNSSLASLRLKSKQHSSFGYSSLQSPGSSLNACQYNS", "length": 302, "header": "tr|A0A1D5P373-1|A0A1D5P373_CHICK Computationally mapped isoform of Homeobox protein OS=Gallus gallus OX=9031 GN=PITX1 PE=3 SV=2 CANONICAL=A0A8V0YNR9-1" }, "locus": { "chromosome": "13", "start_pos": 15222322, "end_pos": 15216277, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030688.1", "url": "https://www.ensembl.org/id/ENSGALT00010030688.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017793.1", "url": "https://www.ensembl.org/id/ENSGALP00010017793.1" } ] } }, { "isoform_ac": "A0A8V0YAL7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNR9/entry#A0A8V0YAL7-1", "sequence": { "sequence": "MDSFKGGMNLERLPESLRPQPSHDMASSFHLQRSSEPRDPIENSASESSDTEVPERKRGKENLTKREGGGGEKNEDGAADDPAKKKKQRRQRTHFTSQQLQELEATFQRNRYPDMSMREEIAVWTNLTEPRVRVWFKNRRAKWRKRERNQQMDLCKNGYVPQFSGLMQPYDDMYAGYPYNNWATKSLTPAPLSTKSFTFFNSMSPLSSQSMFSAPSSISSMNMPSGMGHSAVPGMANSGLNNINNISGSSLNSAMSSPACPYGPPGSPYSVYRDTCNSSLASLRLKSKQHSSFGYSSLQSPGSSLNACQYNS", "length": 312, "header": "tr|A0A8V0YAL7-1|A0A8V0YAL7_CHICK Computationally mapped isoform of Homeobox protein OS=Gallus gallus OX=9031 GN=PITX1 PE=3 SV=1 CANONICAL=A0A8V0YNR9-1" }, "locus": { "chromosome": "13", "start_pos": 15222322, "end_pos": 15216277, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030679.1", "url": "https://www.ensembl.org/id/ENSGALT00010030679.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017788.1", "url": "https://www.ensembl.org/id/ENSGALP00010017788.1" } ] } }, { "isoform_ac": "A0A8V0YGY3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNR9/entry#A0A8V0YGY3-1", "sequence": { "sequence": "MAPKGGVLFGEARCCRIFLKSCQFCPGLFCSSAEKERSGEQKNEDGAADDPAKKKKQRRQRTHFTSQQLQELEATFQRNRYPDMSMREEIAVWTNLTEPRVRVWFKNRRAKWRKRERNQQMDLCKNGYVPQFSGLMQPYDDMYAGYPYNNWATKSLTPAPLSTKSFTFFNSMSPLSSQSMFSAPSSISSMNMPSGMGHSAVPGMANSGLNNINNISGSSLNSAMSSPACPYGPPGSPYSVYRDTCNSSLASLRLKSKQHSSFGYSSLQSPGSSLNACQYNS", "length": 281, "header": "tr|A0A8V0YGY3-1|A0A8V0YGY3_CHICK Computationally mapped isoform of Homeobox protein OS=Gallus gallus OX=9031 GN=PITX1 PE=3 SV=1 CANONICAL=A0A8V0YNR9-1" }, "locus": { "chromosome": "13", "start_pos": 15222322, "end_pos": 15216995, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030672.1", "url": "https://www.ensembl.org/id/ENSGALT00010030672.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017785.1", "url": "https://www.ensembl.org/id/ENSGALP00010017785.1" } ] } }, { "isoform_ac": "A0A8V0YNR9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNR9/entry#A0A8V0YNR9-1", "sequence": { "sequence": "MRERKNNNKAQMPIEPNALSVLKWHRGRTQGRISAEITAGLNAGPRPQRFVPRTHSDPPAPPGREWGRRPREGSAEGGEDLLSVCSVVQRPGQLWGCCRPCLLCKPLNAGRGHPSCDRPFHRVGVSVEALSPSLLFRRAPRAKGDFSRPSPLTPPHPVSRTQPTILFNLAGIGAAEIPPHRRRLSLRERRTARPGGSGRAERPRSFPRGTEVFASRSGTARSSGPLQPPVPGPASRCVRASQCRSDTAEPELGENRGVRSERKREKRRAEKRGRGRRRPGEEEEATEAADPLHQPAAAGAGSHFPAEPLPRYEHAGGDRRVDEPHRAPRPGVVQEPPSQVEKAGAEPADGPVQERLRAAVQRADAALRRHVRRVPLQQLGHQKPHPGAALHQELHLLQLHEPPLLAVHVLGSQQHLLHEHALRDGPLGRAGHGQLRPQQHQQHQRLLAQLGHVLARLSLWAAGLSLQRVPGHL", "length": 473, "header": "tr|A0A8V0YNR9-1|A0A8V0YNR9_CHICK Isoform 1 of Paired like homeodomain 1 OS=Gallus gallus OX=9031 GN=PITX1 PE=4 SV=1 CANONICAL=A0A8V0YNR9-1" }, "locus": { "chromosome": "13", "start_pos": 15222213, "end_pos": 15217830, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030662.1", "url": "https://www.ensembl.org/id/ENSGALT00010030662.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017778.1", "url": "https://www.ensembl.org/id/ENSGALP00010017778.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 153, "start_aa": "Thr", "end_pos": 153, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr153", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:374201", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:374201", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8M9P3F1-1", "protein_name": "Homeobox protein", "gene_name": "pitx1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MNVDMASSFHLPRSASSTRETLENTSSESSDTEAAEKERSVEQRSDDGNADDPKKKKQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRERNQQMDLCKNSYLPQFSGLMQPYDDVYPTYTYNNWTNKGLTPAPLSTKNFTFFNSMSPLTSQSMFSAPSSISSMSMASGMGHSAVPGMPTTGLNNIGNLNGIGGSTINPAMSSSTCPYGPPGSPYSVYRDTCNSSLATLRLKSKQHPSFGYSGLQSPGSSLNACQYNS", "length": 285 }, "evidence": [ { "id": "A0A8V0YNR9", "url": "https://omabrowser.org/oma/group/A0A8V0YNR9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1MU46-1", "protein_name": "Homeobox protein", "gene_name": "PITX1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MDAFKGGMSLERLPEGLRPPPPQPHDMGPAFHLARTADPREPLENSASESSDTELPEKERGGEPKGPEDSGAGGAGCGGAEDPAKKKKQRRQRTHFTSQQLQELEATFQRNRYPDMSMREEIAVWTNLTEPRVRVWFKNRRAKWRKRERNQQLDLCKGGYVPQFSGLVQPYDDVYAAGYSYNNWAAKSLAPAPLSTKSFTFFNSMSPLSSQSMFSAPSSISSMTMPSSMGPGAVPGMPNSGLNNINNLTGSSLNSAMSPGACPYGTPASPYSVYRDTCNSSLASLRLKSKQHSSFGYGGLQGPASGLNACQYNS", "length": 314 }, "evidence": [ { "id": "A0A8V0YNR9", "url": "https://omabrowser.org/oma/group/A0A8V0YNR9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P70314-1", "protein_name": "Pituitary homeobox 1", "gene_name": "Pitx1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDAFKGGMSLERLPEGLRPPPPPPHDMGPSFHLARAADPREPLENSASESSDADLPDKERGGEAKGPEDGGAGSAGCGGGAEDPAKKKKQRRQRTHFTSQQLQELEATFQRNRYPDMSMREEIAVWTNLTEPRVRVWFKNRRAKWRKRERNQQLDLCKGGYVPQFSGLVQPYEDVYAAGYSYNNWAAKSLAPAPLSTKSFTFFNSMSPLSSQSMFSAPSSISSMTMPSSMGPGAVPGMPNSGLNNINNLTGSSLNSAMSPGACPYGTPASPYSVYRDTCNSSLASLRLKSKQHSSFGYGGLQGPASGLNACQYNS", "length": 315 }, "evidence": [ { "id": "A0A8V0YNR9", "url": "https://omabrowser.org/oma/group/A0A8V0YNR9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P78337-1", "protein_name": "Pituitary homeobox 1", "gene_name": "PITX1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDAFKGGMSLERLPEGLRPPPPPPHDMGPAFHLARPADPREPLENSASESSDTELPEKERGGEPKGPEDSGAGGTGCGGADDPAKKKKQRRQRTHFTSQQLQELEATFQRNRYPDMSMREEIAVWTNLTEPRVRVWFKNRRAKWRKRERNQQLDLCKGGYVPQFSGLVQPYEDVYAAGYSYNNWAAKSLAPAPLSTKSFTFFNSMSPLSSQSMFSAPSSISSMTMPSSMGPGAVPGMPNSGLNNINNLTGSSLNSAMSPGACPYGTPASPYSVYRDTCNSSLASLRLKSKQHSSFGYGGLQGPASGLNACQYNS", "length": 314 }, "evidence": [ { "id": "A0A8V0YNR9", "url": "https://omabrowser.org/oma/group/A0A8V0YNR9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q99NA7-1", "protein_name": "Pituitary homeobox 1", "gene_name": "Pitx1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDAFKGGMSLERLPEGLRPPPPPPHDMGPSFHLARTADPREPLENSASESSDADLPDKERGGEAKVPEDGGAGSAGCGSAEDPAKKKKQRRQRTHFTSQQLQELEATFQRNRYPDMSMREEIAVWTNLTEPRVRVWFKNRRAKWRKRERNQQLDLCKGGYVPQFSGLVQPYEDVYAAAGYSYNNWAAKSLAPAPLSTKSFTFFNSMSPLSSQSMFSAPSSISSMTMPSSMGPGSVPGMPNSGLNNINNLTGSSLNSAMSPGACPYGTPASPYSVYRDTCNSSLASLRLKSKQHSSFGYGGLQGPASGLNACQYNS", "length": 315 }, "evidence": [ { "id": "A0A8V0YNR9", "url": "https://omabrowser.org/oma/group/A0A8V0YNR9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNR9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNR9" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNR9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNR9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNR9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNR9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNR9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNR9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 153 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { 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This record is derived from a genomic sequence (NC_052572.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_004949164.1. 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"IPR038820", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038820", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YNT1", "url": "https://www.orthodb.org/?gene=A0A8V0YNT1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YNU9", "url": "https://www.orthodb.org/?gene=A0A8V0YNU9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YNV4", "url": "https://www.orthodb.org/?gene=A0A8V0YNV4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YNV8", "url": "https://www.orthodb.org/?gene=A0A8V0YNV8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YNV9", "url": "https://www.orthodb.org/?gene=A0A8V0YNV9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YNW4", "url": "https://www.orthodb.org/?gene=A0A8V0YNW4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YNW8", "url": "https://www.orthodb.org/?gene=A0A8V0YNW8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YNY2", "url": "https://www.orthodb.org/?gene=A0A8V0YNY2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YQM7", "url": "https://www.orthodb.org/?gene=A0A8V0YQM7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YVQ9", "url": "https://www.orthodb.org/?gene=A0A8V0YVQ9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47899", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47899", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47899:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47899:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF28256", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF28256", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_004949164", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004949164", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YNT1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNT1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YNT1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNT1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YNU9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNU9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YNU9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNU9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YNV4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNV4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YNV4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNV4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YNV8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNV8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YNV8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNV8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YNV9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNV9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YNV9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNV9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YNW4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNW4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YNW4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNW4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YNW8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNW8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YNW8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNW8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YNY2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNY2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YNY2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNY2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQM7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQM7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQM7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQM7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YVQ9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YVQ9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YVQ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YVQ9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MIDIMNLSSPVSHVDHEAKRLCSAKSGSQLLHNSSASELDVAEDLKRKLCQAKEEKVDIIIKHNQELRDYEIQIVKLRSEFEKGEAIRQSLEYALAIAKKDARLTVRTVEEELSDARNKLAELQVFNEKLQQRLVETEKTFHIAQQKWKEQQQRLASEKDDILRTHKDEYELLLKERGELESILQKQNSALQNLSKKMKDMELEHRDCSDLLTRQVHKLEYSAEQEERLKKELEAATDRIKQLEENFEAERAAHLKSKFNLEITQMRIRELEGALQMEKVSQAEALSDLEMIRKEFKEVENAYEREKQKAQENLEKVNRLEREYISTNKQMNEKIEEKKEIIKDLSERLQENEKIHRELQDKLATAKKHQVFVTETYENNMIELKLLLDSFAMSGQRTAGTCKDKDKPSSLSVLETLRYTLTAYQNKLEDTSNELKKMNALCENTTKELEISRDKMCVLSQDLKEARDKLANANKELNHLHTECADKAALIGTLQMELQNVQQRWEEEKVRAAESENEIQKLTRAYKKDMEEKLTFLHGLYQHLVAGCVLIKQPEGILDRFSWSELCAVLQENVDALILDLNRANEKISHLEYICKSKSDTMKELQRSQEDDMSKMAEQMKAQESCWQKQKKYLEQQYSDLLGEVHARAQEYKETAEKNKEKICVLEKRQEELALENLYVKNTLTQIQKEHSSLLAACALLAGALYPLYGRSCAMSIQRDLLQDQVNIYELVNQEIRTLVHILSGVEEEKEDDAKIKKHKFRGLIHVFRRGVIAVLAANRLKVLAQSSSSLFSLINGFKEGIGILVCVGDSKGKHNMSRYNKEGIRCVEALNWFTSPDLLTAVISSVTELQDVISKTDPKSCLSGRLLVSAARNSFSKLMDKLNVIMESVPLDSSRSVTYVEKNSLIQRLAHGLHRINARALEAGSCDRRPIMKSIASLQKQIAEFTQRLHTVEVERCSLRRELAEFKLNFSKMKQEADKAQSLKEQLSLFKQSKLIAHKRFESACEELNNALHWEHQAQVLLNEQAQQLQELNNKLELHSSEEADKNQVLSETVKRLSEAKMELRRKDQSLRQLNRLLTQLEQDKRRLKESIHDAESALCMAAKDRELIINQMKSVEATLHTVRDQTLLSWTAATRNDFTLQLPKLHLETFAVEGLKGGPEVVAFQAMIKSFMDVYQLASSRIDILVKETAPHQLHTAAPMSKLQTACLHESEILQLAGRKCLRWWRWWRQAAAPEPGAERQAGRHSSPRSEPWCPCSKADQELQQLVLSGLPGCRPVLGPDFWQAAWRDLEELVEQNSLSCHCCSSREGQAEARRHPGKKQQDHQGHPKESAKIPLPLGAAPKETQRPAAAAALPGPARATLRKDSGAQTDTSDLLLADAEATGRQCHCAVPDSSSKPQLGQMSCMKVSMHTARKCLDVDLHVFPETVRRPTELLQHPQPTHGAPVSTLKRKCPLHPDQVPRQQHGARAPGCHRAPTYFCSREAWFLPEEEREALELHTCSMKQKHPGNQPAASWEKESTSTYKTAPSEADWAEAGAKGHKRWPWCKNCPGRGESTWSTKAERSSSPPGSVTF", "length": 1575, "header": "tr|A0A8V0YNW8-1|A0A8V0YNW8_CHICK Isoform 1 of Coiled-coil domain containing 171 OS=Gallus gallus OX=9031 GN=CCDC171 PE=4 SV=1 CANONICAL=A0A8V0YNW8-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YNT1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNW8/entry#A0A8V0YNT1-1", "sequence": { "sequence": "MIDIMNLSSPVSHVDHEAKRLCSAKSGSQLLHNSSASELDVAEDLKRKLCQAKEEKVDIIIKHNQELRDYEIQIVKLRSEFEKGEAIRQSLEYALAIAKKDARLTVRTVEEELSDARNKLAELQVFNEKLQQRLVETEKTFHIAQQKWKEQQQRLASEKDDILRTHKDEYELLLKERGELESILQKQNSALQNLSKKMKDMELEHRDCSDLLTRQVHKLEYSAEQEERLKKELEAATDRIKQLEENFEAERAAHLKSKFNLEITQMRIRELEGALQMEKVSQAEALSDLEMIRKEFKEVENAYEREKQKAQENLEKVNRLEREYISTNKQMNEKIEEKKEIIKDLSERLQENEKIHRELQDKLATAKKHQVFVTETYENNMIELKLLLDSFAMSGQRTAGTCKDKDKPSSLSVLETLRYTLTAYQNKLEDTSNELKKMNALCENTTKELEISRDKMCVLSQDLKEARDKLANANKELNHLHTECADKAALIGTLQMELQNVQQRWEEEKVRAAESENEIQKLTRAYKKDMEEKLTFLHGLYQHLVAGCVLIKQPEGILDRFSWSELCAVLQENVDALILDLNRANEKISHLEYICKSKSDTMKELQRSQEDDMSKMAEQMKAQESCWQKQKKYLEQQYSDLLGEVHARAQEYKETAEKNKEKICVLEKRQEELALENLYVKNTLTQIQKEHSSLLAACALLAGALYPLYGRSCAMSIQRDLLQDQVNIYELVNQEIRTLVHILSGVEEEKEDDAKIKKHKFRGLIHVFRRGVIAVLAANRLKVLAQSSSSLFSLINGFKEGIGILVCVGDSKGKHNMSRYNKEGIRCVEALNWFTSPDLLTAVISSVTELQDVISKTDPKSCLSGRLLVSAARNSFSKLMDKLNVIMESVPLDSSRSVTYVEKNSLIQRLAHGLHRINARALEAGSCDRRPIMKSIASLQKQIAEFTQRLHTVEVERCSLRRELAEFKLNFSKMKQEADKAQSLKEQLSLFKQSKLIAHKRFESACEELNNALHWEHQAQVLLNEQAQQLQELNNKLELHSSEEADKNQVLSETVKRLSEAKMELRRKDQSLRQLNRLLTQLEQDKRRLKESIHDAESALCMAAKDRELIINQMKSVEATLHTVRDQTLLSWTAATRNDFTLQLPKLHLETFAVEGLKGGPEVVAFQAMIKSFMDVYQLASSRIDILVKETAPHQLHTAAPMSKLQTACLHESEILQLESLMCLEASLYWKYFNSWNCTQRRRRYQLKVLPCCFFFTVCCCYSATATNVNITDWTVLRGFLLNEHPPIF", "length": 1289, "header": "tr|A0A8V0YNT1-1|A0A8V0YNW8_CHICK Computationally mapped isoform of Coiled-coil domain containing 171 OS=Gallus gallus OX=9031 GN=CCDC171 PE=4 SV=1 CANONICAL=A0A8V0YNW8-1" }, "locus": { "chromosome": "Z", "start_pos": 32566760, "end_pos": 32423195, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034601.1", "url": "https://www.ensembl.org/id/ENSGALT00010034601.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020310.1", "url": "https://www.ensembl.org/id/ENSGALP00010020310.1" } ] } }, { "isoform_ac": "A0A8V0YNU9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNW8/entry#A0A8V0YNU9-1", "sequence": { "sequence": "MIDIMNLSSPVSHVDHEAKRLCSAKSGSQLLHNSSASELDVAEDLKRKLCQAKEEKVDIIIKHNQELRDYEIQIVKLRSEFEKGEAIRQSLEYALAIAKKDARLTVRTVEEELSDARNKLAELQVFNEKLQQRLVETEKTFHIAQQKWKEQQQRLASEKDDILRTHKDEYELLLKERGELESILQKQNSALQNLSKKMKDMELEHRDCSDLLTRQVHKLEYSAEQEERLKKELEAATDRIKQLEENFEAERAAHLKSKFNLEITQMRIRELEGALQMEKVSQAEALSDLEMIRKEFKEVENAYEREKQKAQENLEKVNRLEREYISTNKQMNEKIEEKKEIIKDLSERLQENEKIHRELQDKLATAKKHQVFVTETYENNMIELKLLLDSFAMSGQRTAGTCKDKDKPSSLSVLETLRYTLTAYQNKLEDTSNELKKMNALCENTTKELEISRDKMCVLSQDLKEARDKLANANKELNHLHTECADKAALIGTLQMELQNVQQRWEEEKVRAAESENEIQKLTRAYKKDMEEKLTFLHGLYQHLVAGCVLIKQPEGILDRFSWSELCAVLQENVDALILDLNRANEKISHLEYICKSKSDTMKELQRSQEDDMSKMAEQMKAQESCWQKQKKYLEQQYSDLLGEVHARAQEYKETAEKNKEKICVLEKRQEELALENLYVKNTLTQIQKEHSSLLAACALLAGALYPLYGRSCAMSIQRDLLQDQVNIYELVNQEIRTLVHILSGVEEEKEDDAKIKKHKFRGLIHVFRRGVIAVLAANRLKVLAQSSSSLFSLINGFKEGIGILVCVGDSKGKHNMSRYNKEGIRCVEALNWFTSPDLLTAVISSVTELQDVISKTDPKSCLSGRLLVSAARNSFSKLMDKLNVIMESVPLDSSRSVTYVEKNSLIQRLAHGLHRINARALEAGSCDRRPIMKSIASLQKQIAEFTQRLHTVEVERCSLRRELAEFKLNFSKMKQEADKAQSLKEQLSLFKQSKLIAHKRFESACEELNNALHWEHQAQVLLNEQAQQLQELNNKLELHSSEEADKNQVLSETVKRLSEAKMELRRKDQSLRQLNRLLTQLEQDKRRLKESIHDAESALCMAAKDRELIINQMKSVEATLHTAMIKSFMDVYQLASSRIDILVKETAPHQLHTAAPMSKLQTACLHESEILQLVSLLFNYIFVIWIS", "length": 1188, "header": "tr|A0A8V0YNU9-1|A0A8V0YNU9_CHICK Computationally mapped isoform of Coiled-coil domain containing 171 OS=Gallus gallus OX=9031 GN=CCDC171 PE=4 SV=1 CANONICAL=A0A8V0YNW8-1" }, "locus": { "chromosome": "Z", "start_pos": 32564307, "end_pos": 32423195, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034593.1", "url": "https://www.ensembl.org/id/ENSGALT00010034593.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020307.1", "url": "https://www.ensembl.org/id/ENSGALP00010020307.1" } ] } }, { "isoform_ac": "A0A8V0YNV4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNW8/entry#A0A8V0YNV4-1", "sequence": { "sequence": "MIDIMNLSSPVSHVDHEAKRLCSAKSGSQLLHNSSASELDVAEDLKRKLCQAKEEKVDIIIKHNQELRDYEIQIVKLRSEFEKGEAIRQSLEYALAIAKKDARLTVRTVEEELSDARNKLAELQVFNEKLQQRLVETEKTFHIAQQKWKEQQQRLASEKDDILRTHKDEYELLLKERGELESILQKQNSALQNLSKKMKDMELEHRDCSDLLTRQVHKLEYSAEQEERLKKELEAATDRIKQLEENFEAERAAHLKSKFNLEITQMRIRELEGALQMEKVSQAEALSDLEMIRKEFKEVENAYEREKQKAQENLEKVNRLEREYISTNKQMNEKIEEKKEIIKDLSERLQENEKIHRELQDKLATAKKHQVFVTETYENNMIELKLLLDSFAMSGQRTAGTCKDKDKPSSLSVLETLRYTLTAYQNKLEDTSNELKKMNALCENTTKELEISRDKMCVLSQDLKEARDKLANANKELNHLHTECADKAALIGTLQMELQNVQQRWEEEKVRAAESENEIQKLTRAYKKDMEEKLTFLHGLYQHLVAGCVLIKQPEGILDRFSWSELCAVLQENVDALILDLNRANEKISHLEYICKSKSDTMKELQRSQEDDMSKMAEQMKAQESCWQKQKKYLEQQYSDLLGEVHARAQEYKETAEKNKEKICVLEKRQEELALENLYVKNTLTQIQKEHSSLLAACALLAGALYPLYGRSCAMSIQRDLLQDQVNIYELVNQEIRTLVHILSGVEEEKEDDAKIKKHKFRGLIHVFRRGVIAVLAANRLKVLAQSSSSLFSLINGFKEGIGILVCVGDSKGKHNMSRYNKEGIRCVEALNWFTSPDLLTAVISSVTELQDVISKTDPKSCLSGRLLVSAARNSFSKLMDKLNVIMESVPLDSSRSVTYVEKNSLIQRLAHGLHRINARALEAGSCDRRPIMKSIASLQKQIAEFTQRLHTVEVERCSLRRELAEFKLNFSKMKQEADKAQSLKEQLSLFKQSKLIAHKRFESACEELNNALHWEHQAQVLLNEQAQQLQELNNKLELHSSEEADKNQVLSETVKRLSEAKMELRRKDQSLRQLNRLLTQLEQDKRRLKESIHDAESALCMAAKDRELIINQMKSVEATLHTVRDQTLLSWTAATRNDFTLQLPKLHLETFAVEGLKGGPEVVAFQAMIKSFMDVYQLASSRIDILVKETAPHQLHTAAPMSKLQTACLHESEILQLIL", "length": 1220, "header": "tr|A0A8V0YNV4-1|A0A8V0YNV4_CHICK Computationally mapped isoform of Coiled-coil domain containing 171 OS=Gallus gallus OX=9031 GN=CCDC171 PE=4 SV=1 CANONICAL=A0A8V0YNW8-1" }, "locus": { "chromosome": "Z", "start_pos": 32574513, "end_pos": 32423195, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034610.1", "url": "https://www.ensembl.org/id/ENSGALT00010034610.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020313.1", "url": "https://www.ensembl.org/id/ENSGALP00010020313.1" } ] } }, { "isoform_ac": "A0A8V0YNV8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNW8/entry#A0A8V0YNV8-1", "sequence": { "sequence": "MIDIMNLSSPVSHVDHEAKRLCSAKSGSQLLHNSSASELDVAEDLKRKLCQAKEEKVDIIIKHNQELRDYEIQIVKLRSEFEKGEAIRQSLEYALAIAKKDARLTVRTVEEELSDARNKLAELQVFNEKLQQRLVETEKTFHIAQQKWKEQQQRLASEKDDILRTHKDEYELLLKERGELESILQKQNSALQNLSKKMKDMELEHRDCSDLLTRQVHKLEYSAEQEERLKKELEAATDRIKQLEENFEAERAAHLKSKFNLEITQMRIRELEGALQMEKVSQAEALSDLEMIRKEFKEVENAYEREKQKAQENLEKVNRLEREYISTNKQMNEKIEEKKEIIKDLSERLQENEKIHRELQDKLATAKKHQVFVTETYENNMIELKLLLDSFAMSGQRTAGTCKDKDKPSSLSVLETLRYTLTAYQNKLEDTSNELKKMNALCENTTKELEISRDKMCVLSQDLKEARDKLANANKELNHLHTECADKAALIGTLQMELQNVQQRWEEEKVRAAESENEIQKLTRAYKKDMEEKLTFLHGLYQHLVAGCVLIKQPEGILDRFSWSELCAVLQENVDALILDLNRANEKISHLEYICKSKSDTMKELQRSQEDDMSKMAEQMKAQESCWQKQKKYLEQQYSDLLGEVHARAQEYKETAEKNKEKICVLEKRQEELALENLYVKNTLTQIQKEHSSLLAACALLAGALYPLYGRSCAMSIQRDLLQDQVNIYELVNQEIRTLVHILSGVEEEKEDDAKIKKHKFRGLIHVFRRGVIAVLAANRLKVLAQSSSSLFSLINGFKEGIGILVCVGDSKGKHNMSRYNKEGIRCVEALNWFTSPDLLTAVISSVTELQDVISKTDPKSCLSGRLLVSAARNSFSKLMDKLNVIMESVPLDSSRSVTYVEKNSLIQRLAHGLHRINARALEAGSCDRRPIMKSIASLQKQIAEFTQRLHTVEVERCSLRRELAEFKLNFSKMKQEADKAQSLKEQLSLFKQSKLIAHKRFESACEELNNALHWEHQAQVLLNEQAQQLQELNNKLELHSSEEADKNQVLSETVKRLSEAKMELRRKDQSLRQLNRLLTQLEQDKRRLKESIHDAESALCMAAKDRELIINQMKSVEATLHTVRDQTLLSWTAATRNDFTLQLPKLHLETFAVEGLKGGPEVVAFQAMIKSFMDVYQLASSRIDILVKETAPHQLHTAAPMSKLQTACLHESEILQLICTSVWKDTLLLTLSPGAQQRSAKNRSKYCSSSQSNTHSLWSKKSLLTTMNIYGSCLKSLCERWKDQSTPATSLFYRNKKYQISLVKPYEIFPMNSS", "length": 1315, "header": "tr|A0A8V0YNV8-1|A0A8V0YNV8_CHICK Computationally mapped isoform of Coiled-coil domain containing 171 OS=Gallus gallus OX=9031 GN=CCDC171 PE=4 SV=1 CANONICAL=A0A8V0YNW8-1" }, "locus": { "chromosome": "Z", "start_pos": 32665570, "end_pos": 32423195, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034666.1", "url": "https://www.ensembl.org/id/ENSGALT00010034666.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020344.1", "url": "https://www.ensembl.org/id/ENSGALP00010020344.1" } ] } }, { "isoform_ac": "A0A8V0YNV9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNW8/entry#A0A8V0YNV9-1", "sequence": { "sequence": "MIDIMNLSSPVSHVDHEAKRLCSAKSGSQLLHNSSASELDVAEDLKRKLCQAKEEKVDIIIKHNQELRDYEIQIVKLRSEFEKGEAIRQSLEYALAIAKKDARLTVRTVEEELSDARNKLAELQVFNEKLQQRLVETEKTFHIAQQKWKEQQQRLASEKDDILRTHKDEYELLLKERGELESILQKQNSALQNLSKKMKDMELEHRDCSDLLTRQVHKLEYSAEQEERLKKELEAATDRIKQLEENFEAERAAHLKSKFNLEITQMRIRELEGALQMEKVSQAEALSDLEMIRKEFKEVENAYEREKQKAQENLEKVNRLEREYISTNKQMNEKIEEKKEIIKDLSERLQENEKIHRELQDKLATAKKHQVFVTETYENNMIELKLLLDSFAMSGQRTAGTCKDKDKPSSLSVLETLRYTLTAYQNKLEDTSNELKKMNALCENTTKELEISRDKMCVLSQDLKEARDKLANANKELNHLHTECADKAALIGTLQMELQNVQQRWEEEKVRAAESENEIQKLTRAYKKDMEEKLTFLHGLYQHLVAGCVLIKQPEGILDRFSWSELCAVLQENVDALILDLNRANEKISHLEYICKSKSDTMKELQRSQEDDMSKMAEQMKAQESCWQKQKKYLEQQYSDLLGEVHARAQEYKETAEKNKEKICVLEKRQEELALENLYVKNTLTQIQKEHSSLLAACALLAGALYPLYGRSCAMSIQRDLLQDQVNIYELVNQEIRTLVHILSGVEEEKEDDAKIKKHKFRGLIHVFRRGVIAVLAANRLKVLAQSSSSLFSLINGFKEGIGILVCVGDSKGKHNMSRYNKEGIRCVEALNWFTSPDLLTAVISSVTELQDVISKTDPKSCLSGRLLVSAARNSFSKLMDKLNVIMESVPLDSSRSVTYVEKNSLIQRLAHGLHRINARALEAGSCDRRPIMKSIASLQKQIAEFTQRLHTVEVERCSLRRELAEFKLNFSKMKQEADKAQSLKEQLSLFKQSKLIAHKRFESACEELNNALHWEHQAQVLLNEQAQQLQELNNKLELHSSEEADKNQVLSETVKRLSEAKMELRRKDQSLRQLNRLLTQLEQDKRRLKESIHDAESALCMAAKDRELIINQMKSVEATLHTVRDQTLLSWTAATRNDFTLQLPKLHLETFAVEGLKGGPEVVAFQAMIKSFMDVYQLASSRIDILVKETAPHQLHTAAPMSKLQTACLHESEILQLQLLPEAHQFQGIESQNCRGWKGPQEIIEPNTPAKAGTLTPYDMLLLTTFHKDKLVLSPCHKLLLKDVCALHLNQYVSFLFSFL", "length": 1301, "header": "tr|A0A8V0YNV9-1|A0A8V0YNV9_CHICK Computationally mapped isoform of Coiled-coil domain containing 171 OS=Gallus gallus OX=9031 GN=CCDC171 PE=4 SV=1 CANONICAL=A0A8V0YNW8-1" }, "locus": { "chromosome": "Z", "start_pos": 32577081, "end_pos": 32423195, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034621.1", "url": "https://www.ensembl.org/id/ENSGALT00010034621.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020318.1", "url": "https://www.ensembl.org/id/ENSGALP00010020318.1" } ] } }, { "isoform_ac": "A0A8V0YNW4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNW8/entry#A0A8V0YNW4-1", "sequence": { "sequence": "MIDIMNLSSPVSHVDHEAKRLCSAKSGSQLLHNSSASELDVAEDLKRKLCQAKEEKVDIIIKHNQELRDYEIQIVKLRSEFEKGEAIRQSLEYALAIAKKDARLTVRTVEEELSDARNKLAELQVFNEKLQQRLVETEKTFHIAQQKWKEQQQRLASEKDDILRTHKDEYELLLKERGELESILQKQNSALQNLSKKMKDMELEHRDCSDLLTRQVHKLEYSAEQEERLKKELEAATDRIKQLEENFEAERAAHLKSKFNLEITQMRIRELEGALQMEKVSQAEALSDLEMIRKEFKEVENAYEREKQKAQENLEKVNRLEREYISTNKQMNEKIEEKKEIIKDLSERLQENEKIHRELQDKLATAKKHQVFVTETYENNMIELKLLLDSFAMSGQRTAGTCKDKDKPSSLSVLETLRYTLTAYQNKLEDTSNELKKMNALCENTTKELEISRDKMCVLSQDLKEARDKLANANKELNHLHTECADKAALIGTLQMELQNVQQRWEEEKVRAAESENEIQKLTRAYKKDMEEKLTFLHGLYQHLVAGCVLIKQPEGILDRFSWSELCAVLQENVDALILDLNRANEKISHLEYICKSKSDTMKELQRSQEDDMSKMAEQMKAQESCWQKQKKYLEQQYSDLLGEVHARAQEYKETAEKNKEKICVLEKRQEELALENLYVKNTLTQIQKEHSSLLAACALLAGALYPLYGRSCAMSIQRDLLQDQVNIYELVNQEIRTLVHILSGVEEEKEDDAKIKKHKFRGLIHVFRRGVIAVLAANRLKVLAQSSSSLFSLINGFKEGIGILVCVGDSKGKHNMSRYNKEGIRCVEALNWFTSPDLLTAVISSVTELQDVISKTDPKSCLSGRLLVSAARNSFSKLMDKLNVIMESVPLDSSRSVTYVEKNSLIQRLAHGLHRINARALEAGSCDRRPIMKSIASLQKQIAEFTQRLHTVEVERCSLRRELAEFKLNFSKMKQEADKAQSLKEQLSLFKQSKLIAHKRFESACEELNNALHWEHQAQVLLNEQAQQLQELNNKLELHSSEEADKNQVLSETVKRLSEAKMELRRKDQSLRQLNRLLTQLEQDKRRLKESIHDAESALCMAAKDRELIINQMKSVEATLHTVRDQTLLSWTAATRNDFTLQLPKLHLETFAVEGLKGGPEVVAFQAMIKSFMDVYQLASSRIDILVKETAPHQLHTAAPMSKLQTACLHESEILQLSGSMHATQKKL", "length": 1229, "header": "tr|A0A8V0YNW4-1|A0A8V0YNW4_CHICK Computationally mapped isoform of Coiled-coil domain containing 171 OS=Gallus gallus OX=9031 GN=CCDC171 PE=4 SV=1 CANONICAL=A0A8V0YNW8-1" }, "locus": { "chromosome": "Z", "start_pos": 32578609, "end_pos": 32423195, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034630.1", "url": "https://www.ensembl.org/id/ENSGALT00010034630.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020324.1", "url": "https://www.ensembl.org/id/ENSGALP00010020324.1" } ] } }, { "isoform_ac": "A0A8V0YNW8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNW8/entry#A0A8V0YNW8-1", "sequence": { "sequence": "MIDIMNLSSPVSHVDHEAKRLCSAKSGSQLLHNSSASELDVAEDLKRKLCQAKEEKVDIIIKHNQELRDYEIQIVKLRSEFEKGEAIRQSLEYALAIAKKDARLTVRTVEEELSDARNKLAELQVFNEKLQQRLVETEKTFHIAQQKWKEQQQRLASEKDDILRTHKDEYELLLKERGELESILQKQNSALQNLSKKMKDMELEHRDCSDLLTRQVHKLEYSAEQEERLKKELEAATDRIKQLEENFEAERAAHLKSKFNLEITQMRIRELEGALQMEKVSQAEALSDLEMIRKEFKEVENAYEREKQKAQENLEKVNRLEREYISTNKQMNEKIEEKKEIIKDLSERLQENEKIHRELQDKLATAKKHQVFVTETYENNMIELKLLLDSFAMSGQRTAGTCKDKDKPSSLSVLETLRYTLTAYQNKLEDTSNELKKMNALCENTTKELEISRDKMCVLSQDLKEARDKLANANKELNHLHTECADKAALIGTLQMELQNVQQRWEEEKVRAAESENEIQKLTRAYKKDMEEKLTFLHGLYQHLVAGCVLIKQPEGILDRFSWSELCAVLQENVDALILDLNRANEKISHLEYICKSKSDTMKELQRSQEDDMSKMAEQMKAQESCWQKQKKYLEQQYSDLLGEVHARAQEYKETAEKNKEKICVLEKRQEELALENLYVKNTLTQIQKEHSSLLAACALLAGALYPLYGRSCAMSIQRDLLQDQVNIYELVNQEIRTLVHILSGVEEEKEDDAKIKKHKFRGLIHVFRRGVIAVLAANRLKVLAQSSSSLFSLINGFKEGIGILVCVGDSKGKHNMSRYNKEGIRCVEALNWFTSPDLLTAVISSVTELQDVISKTDPKSCLSGRLLVSAARNSFSKLMDKLNVIMESVPLDSSRSVTYVEKNSLIQRLAHGLHRINARALEAGSCDRRPIMKSIASLQKQIAEFTQRLHTVEVERCSLRRELAEFKLNFSKMKQEADKAQSLKEQLSLFKQSKLIAHKRFESACEELNNALHWEHQAQVLLNEQAQQLQELNNKLELHSSEEADKNQVLSETVKRLSEAKMELRRKDQSLRQLNRLLTQLEQDKRRLKESIHDAESALCMAAKDRELIINQMKSVEATLHTVRDQTLLSWTAATRNDFTLQLPKLHLETFAVEGLKGGPEVVAFQAMIKSFMDVYQLASSRIDILVKETAPHQLHTAAPMSKLQTACLHESEILQLAGRKCLRWWRWWRQAAAPEPGAERQAGRHSSPRSEPWCPCSKADQELQQLVLSGLPGCRPVLGPDFWQAAWRDLEELVEQNSLSCHCCSSREGQAEARRHPGKKQQDHQGHPKESAKIPLPLGAAPKETQRPAAAAALPGPARATLRKDSGAQTDTSDLLLADAEATGRQCHCAVPDSSSKPQLGQMSCMKVSMHTARKCLDVDLHVFPETVRRPTELLQHPQPTHGAPVSTLKRKCPLHPDQVPRQQHGARAPGCHRAPTYFCSREAWFLPEEEREALELHTCSMKQKHPGNQPAASWEKESTSTYKTAPSEADWAEAGAKGHKRWPWCKNCPGRGESTWSTKAERSSSPPGSVTF", "length": 1575, "header": "tr|A0A8V0YNW8-1|A0A8V0YNW8_CHICK Isoform 1 of Coiled-coil domain containing 171 OS=Gallus gallus OX=9031 GN=CCDC171 PE=4 SV=1 CANONICAL=A0A8V0YNW8-1" }, "locus": { "chromosome": "Z", "start_pos": 32675038, "end_pos": 32423195, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034687.1", "url": "https://www.ensembl.org/id/ENSGALT00010034687.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020354.1", "url": "https://www.ensembl.org/id/ENSGALP00010020354.1" } ] } }, { "isoform_ac": "A0A8V0YNY2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNW8/entry#A0A8V0YNY2-1", "sequence": { "sequence": "MIDIMNLSSPVSHVDHEAKRLCSAKSGSQLLHNSSASELDVAEDLKRKLCQAKEEKVDIIIKHNQELRDYEIQIVKLRSEFEKGEAIRQSLEYALAIAKKDARLTVRTVEEELSDARNKLAELQVFNEKLQQRLVETEKTFHIAQQKWKEQQQRLASEKDDILRTHKDEYELLLKERGELESILQKQNSALQNLSKKMKDMELEHRDCSDLLTRQVHKLEYSAEQEERLKKELEAATDRIKQLEENFEAERAAHLKSKFNLEITQMRIRELEGALQMEKVSQAEALSDLEMIRKEFKEVENAYEREKQKAQENLEKVNRLEREYISTNKQMNEKIEEKKEIIKDLSERLQENEKIHRELQDKLATAKKHQVFVTETYENNMIELKLLLDSFAMSGQRTAGTCKDKDKPSSLSVLETLRYTLTAYQNKLEDTSNELKKMNALCENTTKELEISRDKMCVLSQDLKEARDKLANANKELNHLHTECADKAALIGTLQMELQNVQQRWEEEKVRAAESENEIQKLTRAYKKDMEEKLTFLHGLYQHLVAGCVLIKQPEGILDRFSWSELCAVLQENVDALILDLNRANEKISHLEYICKSKSDTMKELQRSQEDDMSKMAEQMKAQESCWQKQKKYLEQQYSDLLGEVHARAQEYKETAEKNKEKICVLEKRQEELALENLYVKNTLTQIQKEHSSLLAACALLAGALYPLYGRSCAMSIQRDLLQDQVNIYELVNQEIRTLVHILSGVEEEKEDDAKIKKHKFRGLIHVFRRGVIAVLAANRLKVLAQSSSSLFSLINGFKEGIGILVCVGDSKGKHNMSRYNKEGIRCVEALNWFTSPDLLTAVISSVTELQDVISKTDPKSCLSGRLLVSAARNSFSKLMDKLNVIMESVPLDSSRSVTYVEKNSLIQRLAHGLHRINARALEAGSCDRRPIMKSIASLQKQIAEFTQRLHTVEVERCSLRRELAEFKLNFSKMKQEADKAQSLKEQLSLFKQSKLIAHKRFESACEELNNALHWEHQAQVLLNEQAQQLQELNNKLELHSSEEADKNQVLSETVKRLSEAKMELRRKDQSLRQLNRLLTQLEQDKRRLKESIHDAESALCMAAKDRELIINQMKSVEATLHTVRDQTLLSWTAATRNDFTLQLPKLHLETFAVEGLKGGPEVVAFQAMIKSFMDVYQLASSRIDILVKETAPHQLHTAAPMSKLQTACLHESEILQLYFSGEAGS", "length": 1226, "header": "tr|A0A8V0YNY2-1|A0A8V0YNY2_CHICK Computationally mapped isoform of Coiled-coil domain containing 171 OS=Gallus gallus OX=9031 GN=CCDC171 PE=4 SV=1 CANONICAL=A0A8V0YNW8-1" }, "locus": { "chromosome": "Z", "start_pos": 32672039, "end_pos": 32423195, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034672.1", "url": "https://www.ensembl.org/id/ENSGALT00010034672.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020347.1", "url": "https://www.ensembl.org/id/ENSGALP00010020347.1" } ] } }, { "isoform_ac": "A0A8V0YQM7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNW8/entry#A0A8V0YQM7-1", "sequence": { "sequence": "MIDIMNLSSPVSHVDHEAKRLCSAKSGSQLLHNSSASELDVAEDLKRKLCQAKEEKVDIIIKHNQELRDYEIQIVKLRSEFEKGEAIRQSLEYALAIAKKDARLTVRTVEEELSDARNKLAELQVFNEKLQQRLVETEKTFHIAQQKWKEQQQRLASEKDDILRTHKDEYELLLKERGELESILQKQNSALQNLSKKMKDMELEHRDCSDLLTRQVHKLEYSAEQEERLKKELEAATDRIKQLEENFEAERAAHLKSKFNLEITQMRIRELEGALQMEKVSQAEALSDLEMIRKEFKEVENAYEREKQKAQENLEKVNRLEREYISTNKQMNEKIEEKKEIIKDLSERLQENEKIHRELQDKLATAKKHQVFVTETYENNMIELKLLLDSFAMSGQRTAGTCKDKDKPSSLSVLETLRYTLTAYQNKLEDTSNELKKMNALCENTTKELEISRDKMCVLSQDLKEARDKLANANKELNHLHTECADKAALIGTLQMELQNVQQRWEEEKVRAAESENEIQKLTRAYKKDMEEKLTFLHGLYQHLVAGCVLIKQPEGILDRFSWSELCAVLQENVDALILDLNRANEKISHLEYICKSKSDTMKELQRSQEDDMSKMAEQMKAQESCWQKQKKYLEQQYSDLLGEVHARAQEYKETAEKNKEKICVLEKRQEELALENLYVKNTLTQIQKEHSSLLAACALLAGALYPLYGRSCAMSIQRDLLQDQVNIYELVNQEIRTLVHILSGVEEEKEDDAKIKKHKFRGLIHVFRRGVIAVLAANRLKVLAQSSSSLFSLINGFKEGIGILVCVGDSKGKHNMSRYNKEGIRCVEALNWFTSPDLLTAVISSVTELQDVISKTDPKSCLSGRLLVSAARNSFSKLMDKLNVIMESVPLDSSRSVTYVEKNSLIQRLAHGLHRINARALEAGSCDRRPIMKSIASLQKQIAEFTQRLHTVEVERCSLRRELAEFKLNFSKMKQEADKAQSLKEQLSLFKQSKLIAHKRFESACEELNNALHWEHQAQVLLNEQAQQLQELNNKLELHSSEEADKNQVLSETVKRLSEAKMELRRKDQSLRQLNRLLTQLEQDKRRLKESIHDAESALCMAAKDRELIINQMKSVEATLHTVRDQTLLSWTAATRNDFTLQLPKLHLETFAVEGLKGGPEVVAFQAMIKSFMDVYQLASSRIDILVKETAPHQLHTAAPMSKLQTACLHESEILQLESRGSSNITMTSS", "length": 1231, "header": "tr|A0A8V0YQM7-1|A0A8V0YQM7_CHICK Computationally mapped isoform of Coiled-coil domain containing 171 OS=Gallus gallus OX=9031 GN=CCDC171 PE=4 SV=1 CANONICAL=A0A8V0YNW8-1" }, "locus": { "chromosome": "Z", "start_pos": 32584640, "end_pos": 32423195, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034642.1", "url": "https://www.ensembl.org/id/ENSGALT00010034642.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020332.1", "url": "https://www.ensembl.org/id/ENSGALP00010020332.1" } ] } }, { "isoform_ac": "A0A8V0YVQ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNW8/entry#A0A8V0YVQ9-1", "sequence": { "sequence": "MIDIMNLSSPVSHVDHEAKRLCSAKSGSQLLHNSSASELDVAEDLKRKLCQAKEEKVDIIIKHNQELRDYEIQIVKLRSEFEKGEAIRQSLEYALAIAKKDARLTVRTVEEELSDARNKLAELQVFNEKLQQRLVETEKTFHIAQQKWKEQQQRLASEKDDILRTHKDEYELLLKERGELESILQKQNSALQNLSKKMKDMELEHRDCSDLLTRQVHKLEYSAEQEERLKKELEAATDRIKQLEENFEAERAAHLKSKFNLEITQMRIRELEGALQMEKVSQAEALSDLEMIRKEFKEVENAYEREKQKAQENLEKVNRLEREYISTNKQMNEKIEEKKEIIKDLSERLQENEKIHRELQDKLATAKKHQVFVTETYENNMIELKLLLDSFAMSGQRTAGTCKDKDKPSSLSVLETLRYTLTAYQNKLEDTSNELKKMNALCENTTKELEISRDKMCVLSQDLKEARDKLANANKELNHLHTECADKAALIGTLQMELQNVQQRWEEEKVRAAESENEIQKLTRAYKKDMEEKLTFLHGLYQHLVAGCVLIKQPEGILDRFSWSELCAVLQENVDALILDLNRANEKISHLEYICKSKSDTMKELQRSQEDDMSKMAEQMKAQESCWQKQKKYLEQQYSDLLGEVHARAQEYKETAEKNKEKICVLEKRQEELALENLYVKNTLTQIQKEHSSLLAACALLAGALYPLYGRSCAMSIQRDLLQDQVNIYELVNQEIRTLVHILSGVEEEKEDDAKIKKHKFRGLIHVFRRGVIAVLAANRLKVLAQSSSSLFSLINGFKEGIGILVCVGDSKGKHNMSRYNKEGIRCVEALNWFTSPDLLTAVISSVTELQDVISKTDPKSCLSGRLLVSAARNSFSKLMDKLNVIMESVPLDSSRSVTYVEKNSLIQRLAHGLHRINARALEAGSCDRRPIMKSIASLQKQIAEFTQRLHTVEVERCSLRRELAEFKLNFSKMKQEADKAQSLKEQLSLFKQSKLIAHKRFESACEELNNALHWEHQAQVLLNEQAQQLQELNNKLELHSSEEADKNQVLSETVKRLSEAKMELRRKDQSLRQLNRLLTQLEQDKRRLKESIHDAESALCMAAKDRELIINQMKSVEATLHTVRDQTLLSWTAATRNDFTLQLPKLHLETFAVEGLKGGPEVVAFQAMIKSFMDVYQLASSRIDILVKETAPHQLHTAAPMSKLQTACLHESEILQLKNRDGLTVLVISERRARQDVLGELLPAMSH", "length": 1248, "header": "tr|A0A8V0YVQ9-1|A0A8V0YVQ9_CHICK Computationally mapped isoform of Coiled-coil domain containing 171 OS=Gallus gallus OX=9031 GN=CCDC171 PE=4 SV=1 CANONICAL=A0A8V0YNW8-1" }, "locus": { "chromosome": "Z", "start_pos": 32626740, "end_pos": 32423195, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034659.1", "url": "https://www.ensembl.org/id/ENSGALT00010034659.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020340.1", "url": "https://www.ensembl.org/id/ENSGALP00010020340.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 193, "end_pos": 195, "annotation": "n_glycosylation_sequon" }, { "start_pos": 33, "end_pos": 35, "annotation": "n_glycosylation_sequon" }, { "start_pos": 444, "end_pos": 446, "annotation": "n_glycosylation_sequon" }, { "start_pos": 6, "end_pos": 8, "annotation": "n_glycosylation_sequon" }, { "start_pos": 816, "end_pos": 818, "annotation": "n_glycosylation_sequon" }, { "start_pos": 970, "end_pos": 972, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 193, "end_pos": 195 }, { "start_pos": 33, "end_pos": 35 }, { "start_pos": 444, "end_pos": 446 }, { "start_pos": 6, "end_pos": 8 }, { "start_pos": 816, "end_pos": 818 }, { "start_pos": 970, "end_pos": 972 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", 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}, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YQM3-1", "uniprot_ac": "A0A8V0YQM3", "uniprot_id": "A0A8V0YQM3_CHICK", "mass": { "chemical_mass": 39723.0, "monoisotopic_mass": 39723.0 }, "refseq": {}, "gene_names": [ { "name": "MFNG", "type": "recommended", "evidence": [ { "id": "A0A8V0YQM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQM3" } ] } ], "protein_names": [ { "name": "O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase", "type": "recommended", "evidence": [ { "id": "A0A8V0YQM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQM3/entry#names_and_taxonomy" } ] }, { "name": "2.4.1.222", "type": "synonym", "evidence": [ { "id": "A0A8V0YQM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQM3/entry#names_and_taxonomy" } ] }, { "name": "O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase", "type": "synonym", "evidence": [ { "id": "A0A8V0YQM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQM3/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQM3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQM3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MFNG", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQM3", "locus": { "chromosome": "1", "start_pos": 51317575, "end_pos": 51295605, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010014388", "url": "https://www.ensembl.org/id/ENSGALG00010014388" } ] } } ], "crossref": [ { "id": "A0A8V0YQM3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YQM3", "database": "AlphaFoldDB", "categories": [] }, { "id": "418042", "url": "https://www.ncbi.nlm.nih.gov/gene/418042", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003378", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003378", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029044", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029044", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:418042", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418042", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "GSHFVDT", "url": "https://omabrowser.org/oma/group/GSHFVDT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YNT6", "url": "https://www.orthodb.org/?gene=A0A8V0YNT6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YNU1", "url": "https://www.orthodb.org/?gene=A0A8V0YNU1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YQL4", "url": "https://www.orthodb.org/?gene=A0A8V0YQL4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YQM3", "url": "https://www.orthodb.org/?gene=A0A8V0YQM3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YVP5", "url": "https://www.orthodb.org/?gene=A0A8V0YVP5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10811", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10811", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02434", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02434", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "70511", "url": "https://www.rhea-db.org/rhea/70511", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "70531", "url": "https://www.rhea-db.org/rhea/70531", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YNT6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNT6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YNT6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNT6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YNU1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNU1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YNU1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNU1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQL4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQL4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQL4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQL4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQM3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQM3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQM3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQM3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YVP5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YVP5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YVP5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YVP5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGRRLIRGLSGAAVFLVSVTLLSVRHRGAQETSGYPGLRERMLENPERRTHEGPEDSKEGGGTGQRDLQVHSLDKYKTEGNLTLGDVFVAVKTTKRFHQSRMELLLDTWISRAREQTYVFTDEEDDALKRRMGDHVVFTNCSTEHSHSALSCKMAAEFDAFLSSDQSWFCHLDDDNYLNPEALLKLLSSYSAMKDVYVGKPSLNRPIRASETLPNNQMKSVRFWFATGGAGFCISRKLARKMMPWASGKNFLSTSELIRLPDDCTIGYIIECKVGGQLLPNRLFHSHLENLQLIPTSDLMQQVTLSYGVFENKLNVIRLSGPFSPQEDPSRLSHPNGTNPPGRERAPLQPHEP", "length": 353, "header": "tr|A0A8V0YQM3-1|A0A8V0YQM3_CHICK Isoform 1 of O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase OS=Gallus gallus OX=9031 GN=MFNG PE=3 SV=1 CANONICAL=A0A8V0YQM3-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YNT6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQM3/entry#A0A8V0YNT6-1", "sequence": { "sequence": "MGRRLIRGLSGAAVFLVSVTLLSVRHRGAQETSGYPGLRERMLENPERRTHEGPEDSKEAVKTTKRFHQSRMELLLDTWISRAREQTYVFTDEEDDALKRRMGDHVVFTNCSTEHSHSALSCKMAAEFDAFLSSDQSWFCHLDDDNYLNPEALLKLLSSYSAMKDVYVGKPSLNRPIRASETLPNNQMKSVRFWFATGGAGFCISRKLARKMMPWASGKNFLSTSELIRLPDDCTIGYIIECKVGGQLLPNRLFHSHLENLQLIPTSDLMQQVTLSYGVFENKLNVIRLSGPFSPQEDPSRFRSLHCHLYPDTPWCLQAVGW", "length": 322, "header": "tr|A0A8V0YNT6-1|A0A8V0YQM3_CHICK Computationally mapped isoform of O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase OS=Gallus gallus OX=9031 GN=MFNG PE=3 SV=1 CANONICAL=A0A8V0YQM3-1" }, "locus": { "chromosome": "1", "start_pos": 51306497, "end_pos": 51296128, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034616.1", "url": "https://www.ensembl.org/id/ENSGALT00010034616.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020315.1", "url": "https://www.ensembl.org/id/ENSGALP00010020315.1" } ] } }, { "isoform_ac": "A0A8V0YNU1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQM3/entry#A0A8V0YNU1-1", "sequence": { "sequence": "MGRRLIRGLSGAAVFLVSVTLLSVRHRGAQETSGYPGLRERMLENPERRTHEGPEDSKEGGGTGQRDLQVHSLDKYKTEGNLTLGDVFVAVKTTKRFHQSRMELLLDTWISRAREQTYVFTDEEDDALKRRMGDHVVFTNCSTEHSHSALSCKMAAEFDAFLSSDQSWFCHLDDDNYLNPEALLKLLSSYSAMKDVYVGKPSLNRPIRASETLPNNQMKSVRFWFATGGAGFCISRKLARKMMPWASGKNFLSTSELIRLPDDCTIGYIIECKVGGQLLPNRLFHSHLENLQLIPTSDLMQQVTLSYGVFENKLNVIRLSGPFSPQEDPSRFRSLHCHLYPDTPWCLQAVGW", "length": 352, "header": "tr|A0A8V0YNU1-1|A0A8V0YNU1_CHICK Computationally mapped isoform of O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase OS=Gallus gallus OX=9031 GN=MFNG PE=3 SV=1 CANONICAL=A0A8V0YQM3-1" }, "locus": { "chromosome": "1", "start_pos": 51306497, "end_pos": 51296128, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034625.1", "url": "https://www.ensembl.org/id/ENSGALT00010034625.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020320.1", "url": "https://www.ensembl.org/id/ENSGALP00010020320.1" } ] } }, { "isoform_ac": "A0A8V0YQL4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQM3/entry#A0A8V0YQL4-1", "sequence": { "sequence": "MGRRLIRGLSGAAVFLVSVTLLSVRHRGAQETSGYPGLRERMLENPERRTHEGPEDSKEGGGTGQRDLQVHSLDKYKTEGNLTLGDVFVAVKTTKRFHQSRMELLLDTWISRAREQTYVFTDEEDDALKRRMGDHVVFTNCSTEHSHSALSCKMAAEFDAFLSSDQSWFCHLDDDNYLNPEALLKLLSSYSAMKDVYVGKPSLNRPIRASETLPNNQMKSVRFWFATGGAGFCISRKLARKMMPWASGKNFLSTSELIRLPDDCTIGYIIECKVGGQLLPNRLFHSHLENLQLIPTSDLMQQVTLSYGVFENKLNVIRLSGPFSPQEDPSRKGTS", "length": 335, "header": "tr|A0A8V0YQL4-1|A0A8V0YQL4_CHICK Computationally mapped isoform of O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase OS=Gallus gallus OX=9031 GN=MFNG PE=3 SV=1 CANONICAL=A0A8V0YQM3-1" }, "locus": { "chromosome": "1", "start_pos": 51305871, "end_pos": 51296128, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034611.1", "url": "https://www.ensembl.org/id/ENSGALT00010034611.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020314.1", "url": "https://www.ensembl.org/id/ENSGALP00010020314.1" } ] } }, { "isoform_ac": "A0A8V0YQM3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQM3/entry#A0A8V0YQM3-1", "sequence": { "sequence": "MGRRLIRGLSGAAVFLVSVTLLSVRHRGAQETSGYPGLRERMLENPERRTHEGPEDSKEGGGTGQRDLQVHSLDKYKTEGNLTLGDVFVAVKTTKRFHQSRMELLLDTWISRAREQTYVFTDEEDDALKRRMGDHVVFTNCSTEHSHSALSCKMAAEFDAFLSSDQSWFCHLDDDNYLNPEALLKLLSSYSAMKDVYVGKPSLNRPIRASETLPNNQMKSVRFWFATGGAGFCISRKLARKMMPWASGKNFLSTSELIRLPDDCTIGYIIECKVGGQLLPNRLFHSHLENLQLIPTSDLMQQVTLSYGVFENKLNVIRLSGPFSPQEDPSRLSHPNGTNPPGRERAPLQPHEP", "length": 353, "header": "tr|A0A8V0YQM3-1|A0A8V0YQM3_CHICK Isoform 1 of O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase OS=Gallus gallus OX=9031 GN=MFNG PE=3 SV=1 CANONICAL=A0A8V0YQM3-1" }, "locus": { "chromosome": "1", "start_pos": 51317575, "end_pos": 51296128, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034631.1", "url": "https://www.ensembl.org/id/ENSGALT00010034631.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020325.1", "url": "https://www.ensembl.org/id/ENSGALP00010020325.1" } ] } }, { "isoform_ac": "A0A8V0YVP5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQM3/entry#A0A8V0YVP5-1", "sequence": { "sequence": "MGRRLIRGLSGAAVFLVSVTLLSVRHRGAQETSGYPGLRERMLENPERRTHEGPEDSKEGGGTGQRDLQVHSLDKYKTEGNLTLGDVFVAVKTTKRFHQSRMELLLDTWISRAREQTYVFTDEEDDALKRRMGDHVVFTNCSTEHSHSALSCKMAAEFDAFLSSDQSWFCHLDDDNYLNPEALLKLLSSYSAMKDVYVGKPSLNRPIRASETLPNNQMKSVRFWFATGGAGFCISRKLARKMMPWASGKNFLSTSELIRLPDDCTIGYIIECKVGGQLLPNRLFHSHLENLQLIPTSDLMQQLFKTGAPVAVADLSTVKWTTAAGD", "length": 326, "header": "tr|A0A8V0YVP5-1|A0A8V0YVP5_CHICK Computationally mapped isoform of MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase OS=Gallus gallus OX=9031 GN=MFNG PE=3 SV=1 CANONICAL=A0A8V0YQM3-1" }, "locus": { "chromosome": "1", "start_pos": 51315996, "end_pos": 51296128, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034629.1", "url": "https://www.ensembl.org/id/ENSGALT00010034629.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020323.1", "url": "https://www.ensembl.org/id/ENSGALP00010020323.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "gga:418042", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418042", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "G3V725-1", "protein_name": "O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase", "gene_name": "Mfng", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MHCRVFRGLAGALFTLLCVGLLSLRYHSSLSLRTMQGTLRLNQPNPGHLELQLGDIFIGVKTTWAFHRSRLDLLLDTWVSRTRQQTFIFTDSPDELLQERLGSHLVVTNCSAEHSHPALSCKMAAEFDAFLVSGLRWFCHVDDDNYVNPKALLQLLRTFPQDHDVYVGKPSLNRPIHASELQSKNRTRLVRFWFATGGAGFCINRQLALKMVPWASGSHFVDTSALIRLPDDCTVGYIIECKLGGHLQPSPLFHSHLETLQLLGTAQLLEQVTLSYGVFEGKLNIIKLPGPFSHEEDPSRFRSLHCLLYPDTPWCPLLAVP", "length": 321 }, "evidence": [ { "id": "A0A8V0YQM3", "url": "https://omabrowser.org/oma/group/A0A8V0YQM3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "I3LAN4-1", "protein_name": "Beta-1,3-N-acetylglucosaminyltransferase", "gene_name": "MFNG", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MQCRPLRGLAGALLTLLCMGLLSLRYHSSLSSQGVRETPRLSPPSPRPPSELQLHDVFIAVKTTRAFHRSRLELLLDTWVSRTREQTFIFTDSLDKGLQERLGSHLVVTNCSAEHSHPALSCKMAAEFDAFLASRLRWFCHVDDDNYLNPKALLKLLKAFPRTRDVYVGRPSLNRPIHASEPQPRNRTRLVQFWFATGGAGFCINRKLALKMAPWASGPRFMDTSALIRLPDDCTVGYIVECKLGGHLQPSPLFHSHLETLQLLRAAQLPEQVTLSYGVFEGKLNVIKLHGPFSPEEDPSRFRSLHCLLYPETPWCPQLVAR", "length": 322 }, "evidence": [ { "id": "A0A8V0YQM3", "url": "https://omabrowser.org/oma/group/A0A8V0YQM3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "O00587-1", "protein_name": "Beta-1,3-N-acetylglucosaminyltransferase manic fringe", "gene_name": "MFNG", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MQCRLPRGLAGALLTLLCMGLLCLRYHLNLSPQRVQGTPELSQPNPGPPKLQLHDVFIAVKTTRAFHRLRLELLLDTWVSRTREQTFVFTDSPDKGLQERLGSHLVVTNCSAEHSHPALSCKMAAEFDTFLASGLRWFCHVDDDNYVNPRALLQLLRAFPLARDVYVGRPSLNRPIHASEPQPHNRTRLVQFWFATGGAGFCINRKLALKMAPWASGSRFMDTSALIRLPDDCTMGYIIECKLGGRLQPSPLFHSHLETLQLLRTAQLPEQVTLSYGVFEGKLNVIKLQGPFSPEEDPSRFRSLHCLLYPDTPWCPQLGAR", "length": 321 }, "evidence": [ { "id": "A0A8V0YQM3", "url": "https://omabrowser.org/oma/group/A0A8V0YQM3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "O09008-1", "protein_name": "Beta-1,3-N-acetylglucosaminyltransferase manic fringe", "gene_name": "Mfng", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MHCRLFRGMAGALFTLLCVGLLSLRYHSSLSQRMIQGALRLNQRNPGPLELQLGDIFIAVKTTWAFHRSRLDLLLDTWVSRIRQQTFIFTDSPDERLQERLGPHLVVTNCSAEHSHPALSCKMAAEFDAFLVSGLRWFCHVDDDNYVNPKALLQLLKTFPQDRDVYVGKPSLNRPIHASELQSKNRTKLVRFWFATGGAGFCINRQLALKMVPWASGSHFVDTSALIRLPDDCTVGYIIECKLGGRLQPSPLFHSHLETLQLLGAAQLPEQVTLSYGVFEGKLNVIKLPGPFSHEEDPSRFRSLHCLLYPDTPWCPLLAAP", "length": 321 }, "evidence": [ { "id": "A0A8V0YQM3", "url": "https://omabrowser.org/oma/group/A0A8V0YQM3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q5YB40-1", "protein_name": "Beta-1,3-N-acetylglucosaminyltransferase manic fringe", "gene_name": "mfng", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MILRRLFHVLPAFAFTLFILVLLDLQLRTRSDQKPQNAHDGHQRTTFISETTAENQHRDGAHEKEKAEGQKWTEVRSTPPLELSDIFIAVKTTGRFHKSRLALLLETWISETKEHTYIFTDSPDADISSEGFNVVVTNCSPEHSHQALSCKMAAEYDYFMASYKKWLCHVDDDNYLNPGALLSLLMAFPADGDIYVGKPSLDRPMRAQELLEGNKTRDVHFWFATGGAGFCLSRNLAERMAPWASGPRFEQTSAVIMLPDDCTVGFIVERRLGISMIHSNMFHSHLENLLLLSPSDIPKQVTLSYGWFESKMNSVELKGVFTKDEDPSRFRTVHCLLYPTTSWCPVALKSALSWNQHVMH", "length": 360 }, "evidence": [ { "id": "A0A8V0YQM3", "url": "https://omabrowser.org/oma/group/A0A8V0YQM3/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQM3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQM3" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQM3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQM3" } ], "pmid": "" }, { "name": "endomembrane system", "id": "GO:0012505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0012505", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQM3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQM3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQM3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQM3" } ], "pmid": "" }, { "name": "O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity", "id": "GO:0033829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQM3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQM3" } ], "pmid": "" }, { "name": "glycosyltransferase activity", "id": "GO:0016757", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016757", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQM3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQM3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "regulation of Notch signaling pathway", "id": "GO:0008593", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008593", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQM3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQM3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 140, "end_pos": 142, "annotation": "n_glycosylation_sequon" }, { "start_pos": 336, "end_pos": 338, "annotation": "n_glycosylation_sequon" }, { "start_pos": 81, "end_pos": 83, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "70511", "name": "", "equation": "3-O-(alpha-L-fucosyl)-L-seryl-[EGF-like domain protein] + UDP-N-acetyl-alpha-D-glucosamine = 3-O-(N-acetyl-beta-D-glucosaminyl-(1->3)-alpha-L-fucosyl)-L-seryl-[EGF-like domain protein] + UDP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A140T8F8-1", "O12972-1", "O12971-1", "A0A8V0YQM3-1" ], "evidence": [ { "id": "70511", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/70511" } ] }, { "id": "70531", "name": "", "equation": "3-O-(alpha-L-fucosyl)-L-threonyl-[EGF-like domain protein] + UDP-N-acetyl-alpha-D-glucosamine = 3-O-(N-acetyl-beta-D-glucosaminyl-(1->3)-alpha-L-fucosyl)-L-threonyl-[EGF-like domain protein] + UDP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A140T8F8-1", "O12972-1", "O12971-1", "A0A8V0YQM3-1" ], "evidence": [ { "id": "70531", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/70531" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A140T8F8", "gene_name": "RFNG", "activity": [ { "ec_number": "2.4.1.222", "activity": "3-O-(alpha-L-fucosyl)-L-seryl-[EGF-like domain protein] + UDP-N-acetyl-alpha-D-glucosamine = 3-O-(N-acetyl-beta-D-glucosaminyl-(1->3)-alpha-L-fucosyl)-L-seryl-[EGF-like domain protein] + UDP + H(+).", "evidence": [ { "id": "A0A140T8F8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A140T8F8" } ] }, { "ec_number": "2.4.1.222", "activity": "", "evidence": [ { "id": "A0A140T8F8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A140T8F8" } ] } ] }, { "uniprot_ac": "A0A8V0YQM3", "gene_name": "MFNG", "activity": [ { "ec_number": "2.4.1.222", "activity": "3-O-(alpha-L-fucosyl)-L-seryl-[EGF-like domain protein] + UDP-N-acetyl-alpha-D-glucosamine = 3-O-(N-acetyl-beta-D-glucosaminyl-(1->3)-alpha-L-fucosyl)-L-seryl-[EGF-like domain protein] + UDP + H(+).", "evidence": [ { "id": "A0A8V0YQM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQM3" } ] }, { "ec_number": "2.4.1.222", "activity": "", "evidence": [ { "id": "A0A8V0YQM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQM3" } ] } ] }, { "uniprot_ac": "O12971", "gene_name": "LFNG", "activity": [ { "ec_number": "2.4.1.222", "activity": "3-O-(alpha-L-fucosyl)-L-seryl-[EGF-like domain protein] + UDP-N-acetyl-alpha-D-glucosamine = 3-O-(N-acetyl-beta-D-glucosaminyl-(1->3)-alpha-L-fucosyl)-L-seryl-[EGF-like domain protein] + UDP + H(+).", "evidence": [ { "id": "O12971", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O12971" } ] }, { "ec_number": "2.4.1.222", "activity": "", "evidence": [ { "id": "O12971", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O12971" } ] } ] }, { "uniprot_ac": "O12972", "gene_name": "RFNG", "activity": [ { "ec_number": "2.4.1.222", "activity": "3-O-(alpha-L-fucosyl)-L-seryl-[EGF-like domain protein] + UDP-N-acetyl-alpha-D-glucosamine = 3-O-(N-acetyl-beta-D-glucosaminyl-(1->3)-alpha-L-fucosyl)-L-seryl-[EGF-like domain protein] + UDP + H(+).", "evidence": [ { "id": "O12972", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O12972" } ] }, { "ec_number": "2.4.1.222", "activity": "", "evidence": [ { "id": "O12972", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O12972" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YQM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQM3" }, { "id": "PF02434", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02434" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Fringe-like glycosyltransferase", "eco_id": "ECO_0000259", "start_pos": 81, "end_pos": 331, "start_aa": "Asn", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.4.1.222", "ec_name": "3-O-(alpha-L-fucosyl)-L-seryl-[EGF-like domain protein] + UDP-N-acetyl-alpha-D-glucosamine = 3-O-(N-acetyl-beta-D-glucosaminyl-(1->3)-alpha-L-fucosyl)-L-seryl-[EGF-like domain protein] + UDP + H(+).", "evidence": [ { "id": "2.4.1.222", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.1.222" }, { "id": "2.4.1.222", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.4.1.222" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 140, "end_pos": 142 }, { "start_pos": 336, "end_pos": 338 }, { "start_pos": 81, "end_pos": 83 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": 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"uniprot_ac": "A0A8V0YNU4", "uniprot_id": "A0A8V0YNU4_CHICK", "mass": { "chemical_mass": 40926.0, "monoisotopic_mass": 40926.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Dilute domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A8V0YNU4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNU4/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNU4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNU4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNU4", "locus": {} } ], "crossref": [ { "id": "A0A8V0YNU4", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YNU4", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR002710", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002710", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052072", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052072", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR16027", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16027", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16027:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16027:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01843", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01843", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YNU4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNU4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YNU4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNU4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEGGPAAQCPTAAFRAPHGMLDYDPKDEALLIRRLITELDLTKMAAGVPCLPAYVLAMCIRRADDVNDARRMQSLLNASIAAIKDVTQGRRELALSSFWLANCCRLLQCLKQRPGSAPPELAALCEALYAQLCANADAALQPMVVPAVLESQTLWGLQAVGRRPQRRSPSHSLGGLIGRLDAVCRVTGEHGLEPQLVLQLFRHLFYRVTAWALNHLLLRKDLCSWSTGLQLRFNISQLEEWLRKQQLQHSGALEALQPLIQAAQLLQLSKKSPEDAEAICKHCTELSSQQIVKLLTLYSPVDEFEERVSVAFIRTVQAKLKDRDDPNQLLMDSKRTFPLLIPYNPTPVPLDSIRVPSYLNLDFLIPL", "length": 367, "header": "tr|A0A8V0YNU4-1|A0A8V0YNU4_CHICK Isoform 1 of Dilute domain-containing protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0YNU4-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YNU4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNU4/entry#A0A8V0YNU4-1", "sequence": { "sequence": "MEGGPAAQCPTAAFRAPHGMLDYDPKDEALLIRRLITELDLTKMAAGVPCLPAYVLAMCIRRADDVNDARRMQSLLNASIAAIKDVTQGRRELALSSFWLANCCRLLQCLKQRPGSAPPELAALCEALYAQLCANADAALQPMVVPAVLESQTLWGLQAVGRRPQRRSPSHSLGGLIGRLDAVCRVTGEHGLEPQLVLQLFRHLFYRVTAWALNHLLLRKDLCSWSTGLQLRFNISQLEEWLRKQQLQHSGALEALQPLIQAAQLLQLSKKSPEDAEAICKHCTELSSQQIVKLLTLYSPVDEFEERVSVAFIRTVQAKLKDRDDPNQLLMDSKRTFPLLIPYNPTPVPLDSIRVPSYLNLDFLIPL", "length": 367, "header": "tr|A0A8V0YNU4-1|A0A8V0YNU4_CHICK Isoform 1 of Dilute domain-containing protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0YNU4-1" }, "locus": { "chromosome": "W", "start_pos": 272641, "end_pos": 135761, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033298.1", "url": "https://www.ensembl.org/id/ENSGALT00010033298.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019656.1", "url": "https://www.ensembl.org/id/ENSGALP00010019656.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], 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"total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YNX7-1", "uniprot_ac": "A0A8V0YNX7", "uniprot_id": "A0A8V0YNX7_CHICK", "mass": { "chemical_mass": 36382.0, "monoisotopic_mass": 36382.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "G-protein coupled receptors family 1 profile domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A8V0YNX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNX7/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNX7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNX7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNX7", "locus": {} } ], "crossref": [ { "id": "A0A8V0YNX7", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YNX7", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd14982", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14982", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR24232", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24232", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24232:SF91", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24232:SF91", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00001", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00001", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YNX7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNX7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YNX7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNX7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGGVKGSGALQGSSGPLDEPCIGTVLDAAPSLVLQALDPVQFVLLPIVYCLVLCVGLPGNLAALLVFLQRGKVRKAARIYLINLTLADILFNLTLPLWIPYYLAGGDWLLPEAACRLAGAAYYLATYSAVTFMALISVDRLCAVRRALPLAGRRGAALACGAAWLLGLGCAAPALTARQTSPARAGATACFEQHARQRAYAYAMVAFFAVAFLVVLGAYTSIARSLSSAAVPSPGSHRQQARAMALGMLLVFAVCVAPYHLMLAPWVGSRPPTPPCGPPAALDVLHVLSVALLSLNSCLDPLVYCFCIRRFRADLGRTLRAAAHCLPLSPSAPHGSAPGGRAISFTST", "length": 348, "header": "tr|A0A8V0YNX7-1|A0A8V0YNX7_CHICK Isoform 1 of G-protein coupled receptors family 1 profile domain-containing protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0YNX7-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YNX7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNX7/entry#A0A8V0YNX7-1", "sequence": { "sequence": "MGGVKGSGALQGSSGPLDEPCIGTVLDAAPSLVLQALDPVQFVLLPIVYCLVLCVGLPGNLAALLVFLQRGKVRKAARIYLINLTLADILFNLTLPLWIPYYLAGGDWLLPEAACRLAGAAYYLATYSAVTFMALISVDRLCAVRRALPLAGRRGAALACGAAWLLGLGCAAPALTARQTSPARAGATACFEQHARQRAYAYAMVAFFAVAFLVVLGAYTSIARSLSSAAVPSPGSHRQQARAMALGMLLVFAVCVAPYHLMLAPWVGSRPPTPPCGPPAALDVLHVLSVALLSLNSCLDPLVYCFCIRRFRADLGRTLRAAAHCLPLSPSAPHGSAPGGRAISFTST", "length": 348, "header": "tr|A0A8V0YNX7-1|A0A8V0YNX7_CHICK Isoform 1 of G-protein coupled receptors family 1 profile domain-containing protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0YNX7-1" }, "locus": { "chromosome": "23", "start_pos": 4774684, "end_pos": 4773123, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033370.1", "url": "https://www.ensembl.org/id/ENSGALT00010033370.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019686.1", "url": "https://www.ensembl.org/id/ENSGALP00010019686.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 273, "start_aa": "Thr", "end_pos": 273, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr273", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNX7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNX7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNX7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNX7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "G protein-coupled receptor signaling pathway", "id": "GO:0007186", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007186", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNX7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNX7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 83, "end_pos": 85, "annotation": "n_glycosylation_sequon" }, { "start_pos": 92, "end_pos": 94, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YNX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNX7" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 59, "end_pos": 304, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 273 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 83, "end_pos": 85 }, { "start_pos": 92, "end_pos": 94 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YNY5-1", "uniprot_ac": "A0A8V0YNY5", "uniprot_id": "A0A8V0YNY5_CHICK", "mass": { "chemical_mass": 40129.0, "monoisotopic_mass": 40129.0 }, "refseq": { "ac": "XP_015141168", "name": "uncharacterized protein C4orf19 homolog isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015141168" }, "gene_names": [ { "name": "C4ORF19", "type": "recommended", "evidence": [ { "id": "A0A8V0YNY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNY5" } ] }, { "name": "C4ORF19", "type": "synonym", "evidence": [ { "id": "XP_015141168", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015141168" } ] } ], "protein_names": [ { "name": "Chromosome 4 open reading frame 19", "type": "synonym", "evidence": [ { "id": "A0A8V0YNY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNY5/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein C4orf19 homolog isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015141168", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015141168" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052535.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015141168.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015141168", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015141168" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNY5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNY5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "C4ORF19", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNY5", "locus": {} } ], "crossref": [ { "id": "A0A8V0YNY5", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YNY5", "database": "AlphaFoldDB", "categories": [] }, { "id": "101747284", "url": "https://www.ncbi.nlm.nih.gov/gene/101747284", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR031528", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031528", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:101747284", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:101747284", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YPQLWGS", "url": "https://omabrowser.org/oma/group/YPQLWGS/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YNY5", "url": "https://www.orthodb.org/?gene=A0A8V0YNY5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16106", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16106", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16106:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16106:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15770", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15770", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015141168", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015141168", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YNY5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNY5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YNY5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNY5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MIFTHLNNLHQYGSRHLNQILKAVDGVQSERLKKIQMGCRCCKMIQSYIFDPEELQSPGCTHEGNSYKQDEQRSNKFKFKQNCEIKEQKKEIQKDELKGTGIKNRVNSTGETLWNHRGDAFQDDSLVKCVAKLDVAVNGSNSHAGVHPILSPSTNSAKEASEQSTSSQPAEPSSVNTGDFHSKPNECGQELDLGAGSHRKADCSQTNSIRGVKPWSIEDSNFLKGSAVLETQNNDAIKLPDIDYCQNGNQIRNYVEKDSISVNYTHPDQMNKHLAMQGQDLHVTPPLQTKESSIEPFNTDSAGLSEDIPNGIAAMAVPTAAQAPTHHSHRDINGQTEEEDAEVAAALAALEAATAGEDLEEDDEY", "length": 365, "header": "tr|A0A8V0YNY5-1|A0A8V0YNY5_CHICK Isoform 1 of Chromosome 4 open reading frame 19 OS=Gallus gallus OX=9031 GN=C4ORF19 PE=4 SV=1 CANONICAL=A0A8V0YNY5-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YNY5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNY5/entry#A0A8V0YNY5-1", "sequence": { "sequence": "MIFTHLNNLHQYGSRHLNQILKAVDGVQSERLKKIQMGCRCCKMIQSYIFDPEELQSPGCTHEGNSYKQDEQRSNKFKFKQNCEIKEQKKEIQKDELKGTGIKNRVNSTGETLWNHRGDAFQDDSLVKCVAKLDVAVNGSNSHAGVHPILSPSTNSAKEASEQSTSSQPAEPSSVNTGDFHSKPNECGQELDLGAGSHRKADCSQTNSIRGVKPWSIEDSNFLKGSAVLETQNNDAIKLPDIDYCQNGNQIRNYVEKDSISVNYTHPDQMNKHLAMQGQDLHVTPPLQTKESSIEPFNTDSAGLSEDIPNGIAAMAVPTAAQAPTHHSHRDINGQTEEEDAEVAAALAALEAATAGEDLEEDDEY", "length": 365, "header": "tr|A0A8V0YNY5-1|A0A8V0YNY5_CHICK Isoform 1 of Chromosome 4 open reading frame 19 OS=Gallus gallus OX=9031 GN=C4ORF19 PE=4 SV=1 CANONICAL=A0A8V0YNY5-1" }, "locus": { "chromosome": "4", "start_pos": 69404195, "end_pos": 69382367, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034745.1", "url": "https://www.ensembl.org/id/ENSGALT00010034745.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020374.1", "url": "https://www.ensembl.org/id/ENSGALP00010020374.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:101747284", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:101747284", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "F1MD47-1", "protein_name": "Chromosome 6 C4orf19 homolog", "gene_name": "C6H4orf19", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGCRCCKMIQSYLFDPVHVPSPGYVNEVNSCKLDEEDTLKLKDKQSSEILVHKGDPPNEGSKRTASGSGTAAPQEPYGPPRGPLLSEDTVGGPCAEKTSGAINGLGPAAVLQLIGEPGPPQGARDSWASAANKGHPTQPFLEGGSARELDCMQLGSGETQVIRNGGSGTPSTAGLAAWEVPAQVLQIPTPDYPPFSSSAEDNTDHVDHQEKDRLFKIHSEKEPQEGAHPPAGECGLNMPFSIKRSWDSLNEAVTTEIPSVYFDKDDPAQDVPVVDSRNGWEEAPGSPGDGSWETADEDAEVAEALAALEAATAGEDVDEAE", "length": 321 }, "evidence": [ { "id": "A0A8V0YNY5", "url": "https://omabrowser.org/oma/group/A0A8V0YNY5/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1S4L8-1", "protein_name": "Chromosome 8 C4orf19 homolog", "gene_name": "C8H4orf19", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGCRCCKMIQSYLFDPVQVPSPGYVNEVNSCKLDEDDTVKLKGRQSGEVLVPKSDLQSKDSVRTASTSGQDAPPEPCRPPQGPLPHGDPAGGPCAEKPGSAVNGLGPATALQLPGDPKLPQGDGGSQASRANRVPQSQPFLEGDNARALDCVLLALEETQVMGDGDSRAPSTAGHPPREVQDHGLRIPTPDYPQFDGPAEDSVDGEEKDCLFESPSEEEPQEGTYPRAREQGLNMPFSVKRSWDSLNEAVATEILSAYFKEDPTQDVPAVDSRNGWQEAPGSPEDRSGEPAEEDAEVAEALAALEAATAGEEVDEVD", "length": 317 }, "evidence": [ { "id": "A0A8V0YNY5", "url": "https://omabrowser.org/oma/group/A0A8V0YNY5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q6AYA8-1", "protein_name": "PDCD10 and GCKIII kinases-associated protein 1", "gene_name": "Pgcka1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGCRCCKMIQSYLFDPVQVPSPGFVNEVNNCKLEEDDTVRLKGTQNSEVEVPGSTLHSGSLSKPDSSGSTTGLPCQGSLTQEDSEERPCVEKHGIVNGIRPTATLQSVRSPRPQQVDSVSWASSPWVATIDSAHPAQPFLEGEDYRKQSCMLPTLEGTQMVGHGDSRAPAEALAVADHIPYIPAPDYPQVWSPEVDNVNPEEKDCLFENHSEVEPLPGIHPRVSQQGLSMPFSLKRSWDSLNEAGTTEVLSVYFKEEDPTQPTPVADPGNEREDPHTYNGNKEGAVVDEDAEVAEALAALEAATAGEDADDAD", "length": 313 }, "evidence": [ { "id": "A0A8V0YNY5", "url": "https://omabrowser.org/oma/group/A0A8V0YNY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8IY42-1", "protein_name": "PDCD10 and GCKIII kinases-associated protein 1", "gene_name": "PGCKA1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGCRCCKIIQSYLFDPVQVPSPGYVNEVNSCKLDEDDTDKLKGKWSSEVLVQKNDPQRQGSKKTESSSRTADPWEPCWPHQGPLPQGDAGGEHHACGVNGIGPAATPQPTGNSSPTQDDRGSWASTANTVPPTQPFLEGGGTRKQDCVLLASEGTQVMRNGDSRAPSEAESFALEVQDHVFQIPAPDYLQHWGPAGDNVDHNEKDCVFKNHTEDESLEGIQPPVGEHGLNTPFSVRRSWDSLNEDVETEVLSICFNEKGPVHAMPVVDSGNRQEDTHGSDGDGDGEIVDEDAAVAEALAALEAATAGEDLDETD", "length": 314 }, "evidence": [ { "id": "A0A8V0YNY5", "url": "https://omabrowser.org/oma/group/A0A8V0YNY5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q99K99-1", "protein_name": "PDCD10 and GCKIII kinases-associated protein 1", "gene_name": "Pgcka1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGCRCCKMIQSYLFDPVQVPSPGFVNEVNNCKLEEDDTVRLKGTQNSEVEVPRNALHDGSLSNSESRGSTTGLPHQGPLPQEDSEERPCVEKQGIVNGISPTATLQSVRSSRLHQVDNSSWASSPWVATIDSAHLAQPFLEGEDYRKQSCLLPTLEGTQMVGHGDCRAPAEALAVADHIPYIPAPDYPQLWSPTVDNADPEEKDCLFENHSEVEPLPGIQPRVSQLGLNVPFSLQRSWDSLNEAGTTEVLSDYFKEEGPTHPTPAADSGSEREDPHTYNGDREGVVVDEDAEVAEALAALEAATAGEDADDAD", "length": 313 }, "evidence": [ { "id": "A0A8V0YNY5", "url": "https://omabrowser.org/oma/group/A0A8V0YNY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 107, "end_pos": 109, "annotation": "n_glycosylation_sequon" }, { "start_pos": 138, "end_pos": 140, "annotation": "n_glycosylation_sequon" }, { "start_pos": 263, "end_pos": 265, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 107, "end_pos": 109 }, { "start_pos": 138, "end_pos": 140 }, { "start_pos": 263, "end_pos": 265 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YNZ2-1", "uniprot_ac": "A0A8V0YNZ2", "uniprot_id": "A0A8V0YNZ2_CHICK", "mass": { "chemical_mass": 145357.0, "monoisotopic_mass": 145357.0 }, "refseq": { "ac": "XP_004943494", "name": "probable guanine nucleotide exchange factor MCF2L2 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004943494" }, "gene_names": [ { "name": "MCF2L2", "type": "recommended", "evidence": [ { "id": "A0A8V0YNZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNZ2" } ] }, { "name": "MCF2L2", "type": "synonym", "evidence": [ { "id": "XP_004943494", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004943494" } ] } ], "protein_names": [ { "name": "MCF.2 cell line derived transforming sequence-like 2", "type": "synonym", "evidence": [ { "id": "A0A8V0YNZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNZ2/entry#names_and_taxonomy" } ] }, { "name": "probable guanine nucleotide exchange factor MCF2L2 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_004943494", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004943494" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052540.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004943494", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004943494" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNZ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNZ2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MCF2L2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNZ2", "locus": { "chromosome": "9", "start_pos": 16067712, "end_pos": 15916303, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010016355", "url": "https://www.ensembl.org/id/ENSGALG00010016355" } ] } } ], "crossref": [ { "id": "ENSGALG00000008744", "url": 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"categories": [ "Protein" ] }, { "id": "A0A1D5PJM8-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PJM8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YNY6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNY6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YNY6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNY6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YNZ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNZ2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YNZ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNZ2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YVH0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YVH0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YVH0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YVH0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YVI0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YVI0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YVI0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YVI0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YXD9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXD9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YXD9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXD9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YXE4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXE4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YXE4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXE4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YXG9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXG9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YXG9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXG9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z291", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z291", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z291-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z291-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z296", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z296", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z296-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z296-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASRCRKCGQQVPRNLPFTAVRITEGEMKSYHDFIGGCIRLECMAKKDEIMQQEIRPLVAVDIIEQLHRQFAILSGGRGKDGAPIITFPEFAGFSEIPDEDFLNVVTYLTSIPSLEAASIGFIIIIDRRRDKWSAVKASLTRIAGAFPGNLQLVFVLRPSRFIQRAIADIGIKLYRDDFKMKVPIIMLNSVSDLHGYIDKCQLTRELGGTLEYGHSQWIHHRTAIENFAMTVKTTAQMLQTFGTDLAETELPNDVQCTEELLSAHTDHHSKLKDELKLAVKQGATLLTCIREPVTRSANSKLSPDELENVATVERLLAQLDETEKAFDQFWTKHHLKLEQCLQLRHFEHDFREVKLTLDNLMEAQAGFSDVGDSVTRVEHLLREQKQLEEKGQEPLEKAQTLALHGEQLIQNNHYAVDSIRPKCVELRRICDDFTNETKKKYDILGKSLELHKQLDKASQWCEAGIYLLASQAVDKCQSQEGAETALVEIEKFLATAKEHQLSNPKEFYNQFDTILTPEIKANAQRILQKLEDVQEMFDKRQVSLKKLAAKQTRPVQPVAPHPESSPKRASPKTTRPAGVATNRRSAEITCPPKSISEAELSKKKSIKKTKGGIKIEVMHEASQGGSSRVLVMSESDENLSTRRSHIINELIETERVYVEELQSIIEGYASEMDNPSLLHLIPSVLQNKKDILFGNLPEIYEFHNRIFLKELENCIENPELLARCFLKRKEDLQIYEKYCQNKPRSEALWRQCGDSIFFQECQRKLDHKLSLDAYLLKPVQRITKYQLLLKEMLKCSKNSEGTAELEEALATVLDIIKSVNDSMHQIAITGYEGDVSELGKLLMQGSFNVWTDHKKGHNKVKDLARFKPMQRHLFLYTKMLLFCKKREENTDGHEKTASYSFKNSLKMSTVGITENVKGDNKKFEIWYNGREEVYIIQASSVELKNTWISEIRKVLTGQLEACREASQLHQRITESVYHAPMNSSNITRYSRKSSSIYENKSETSNVEASNNKNRNSSPSARQKRVDASTSLNLERTALARKRFTLQGLSNRRAPPKDPESKEREVARRFSLASSISTTVNASAVTKGPLVPAVKVKRHEIKSDPTPLGFEDAFENTILAQTKCSTGSTTRPVPRSASQTGWPSRQMPSLDTFEDFEAIPSSMDELSNSSDMEEETNPNNGTNLFRVEGSFDSCFPDSLTLEDGDLVQFVQEGENGQWLVKKLVSEKSEWVPSSILQPAEGDTNNIIKNSNADMYNDSCSTASVESDTKESEVAKSFPAEQRAGS", "length": 1285, "header": "tr|A0A8V0YNZ2-1|A0A8V0YNZ2_CHICK Isoform 1 of MCF.2 cell line derived transforming sequence-like 2 OS=Gallus gallus OX=9031 GN=MCF2L2 PE=3 SV=1 CANONICAL=A0A8V0YNZ2-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PJM8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNZ2/entry#A0A1D5PJM8-1", "sequence": { "sequence": "MLCSSLCEMLFWLKEEEMSHQELTQRLTTVITHVDEIMQQEIRPLVAVDIIEQLHRQFAILSGGRGKDGAPIITFPEFAGFSEIPDEDFLNVVTYLTSIPSLEAASIGFIIIIDRRRDKWSAVKASLTRIAGAFPGNLQLVFVLRPSRFIQRAIADIGIKLYRDDFKMKVPIIMLNSVSDLHGYIDKCQLTRELGGTLEYGHSQWIHHRTAIENFAMTVKTTAQMLQTFGTDLAETELPNDVQCTEELLSAHTDHHSKLKDELKLAVKQGATLLTCIREPVTRSANSKLSPDELENVATVERLLAQLDETEKAFDQFWTKHHLKLEQCLQLRHFEHDFREVKLTLDNLMEAQAGFSDVGDSVTRVEHLLREQKQLEEKGQEPLEKAQTLALHGEQLIQNNHYAVDSIRPKCVELRRICDDFTNETKKKYDILGKSLELHKQLDKASQWCEAGIYLLASQAVDKCQSQEGAETALVEIEKFLATAKEHQLSNPKEFYNQFDTILTPEIKANAQRILQKLEDVQEMFDKRQVSLKKLAAKQTRPVQPVAPHPESSPKRASPKTTRPAGVATNRRSAEITCPPKSISEAELSKKKSIKKTKGGIKIEVMHEASQGGSSRVLVMSESDENLSTRRSHIINELIETERVYVEELQSIIEGYASEMDNPSLLHLIPSVLQNKKDILFGNLPEIYEFHNRIFLKELENCIENPELLARCFLKRKEDLQIYEKYCQNKPRSEALWRQCGDSIFFQECQRKLDHKLSLDAYLLKPVQRITKYQLLLKEMLKCSKNSEGTAELEEALATVLDIIKSVNDSMHQIAITGYEGDVSELGKLLMQGSFNVWTDHKKGHNKVKDLARFKPMQRHLFLYTKMLLFCKKREENTDGHEKTASYSFKNSLKMSTVGITENVKGDNKKFEIWYNGREEVYIIQASSVELKNTWISEIRKVLTGQLEACREASQLHQRITESVYHAPMNSSNITRYSRKSSSIYENKSETSNVEASNNKNRNSSPSARQKRGWPSRQMPSLDTFEDFEAIPSSMDELSNSSDMEEETNPNNGTNLFRVEGSFDSCFPDSLTLEDGDLVQFVQEGENGQWLVKKLVSEKSEWVPSSILQPAEGDTNNIIKNSNADMYNDSCSTASVESDTKESEVAKSFPAEQRAGS", "length": 1157, "header": "tr|A0A1D5PJM8-1|A0A1D5PJM8_CHICK Computationally mapped isoform of MCF.2 cell line derived transforming sequence-like 2 OS=Gallus gallus OX=9031 GN=MCF2L2 PE=3 SV=2 CANONICAL=A0A8V0YNZ2-1" }, "locus": { "chromosome": "9", "start_pos": 16066980, "end_pos": 15923580, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010039432.1", "url": "https://www.ensembl.org/id/ENSGALT00010039432.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010022751.1", "url": "https://www.ensembl.org/id/ENSGALP00010022751.1" } ] } }, { "isoform_ac": "A0A8V0YNY6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNZ2/entry#A0A8V0YNY6-1", "sequence": { "sequence": "MQQEIRPLVAVDIIEQLHRQFAILSGGRGKDGAPIITFPEFAGFSEIPDEDFLNVVTYLTSIPSLEAASIGFIIIIDRRRDKWSAVKASLTRIAGAFPGNLQLVFVLRPSRFIQRAIADIGIKLYRDDFKMKVPIIMLNSVSDLHGYIDKCQLTRELGGTLEYGHSQWIHHRTAIENFAMTVKTTAQMLQTFGTDLAETELPNDVQCTEELLSAHTDHHSKLKDELKLAVKQGATLLTCIREPVTRSANSKLSPDELENVATVERLLAQLDETEKAFDQFWTKHHLKLEQCLQLRHFEHDFREVKLTLDNLMEAQAGFSDVGDSVTRVEHLLREQKQLEEKGQEPLEKAQTLALHGEQLIQNNHYAVDSIRPKCVELRRICDDFTNETKKKYDILGKSLELHKQLDKASQWCEAGIYLLASQAVDKCQSQEGAETALVEIEKFLATAKEHQLSNPKEFYNQFDTILTPEIKANAQRILQKLEDVQEMFDKRQVSLKKLAAKQTRPVQPVAPHPESSPKRASPKTTRPAGVATNRRSAEITCPPKSISEAELSKKKSIKKTKGGIKIEVMHEASQGGSSRVLVMSESDENLSTRRSHIINELIETERVYVEELQSIIEGYASEMDNPSLLHLIPSVLQNKKDILFGNLPEIYEFHNRIFLKELENCIENPELLARCFLKRKEDLQIYEKYCQNKPRSEALWRQCGDSIFFQECQRKLDHKLSLDAYLLKPVQRITKYQLLLKEMLKCSKNSEGTAELEEALATVLDIIKSVNDSMHQIAITGYEGDVSELGKLLMQGSFNVWTDHKKGHNKVKDLARFKPMQRHLFLYTKMLLFCKKREENTDGHEKTASYSFKNSLKMSTVGITENVKGDNKKFEIWYNGREEVYIIQASSVELKNTWISEIRKVLTGQLEACREASQLHQRITESVYHAPMNSSNITRYSRKSSSIYENKSETSNVEASNNKNRNSSPSARQKRGWPSRQMPSLDTFEDFEAIPSSMDELSNSSDMEEETNPNNGTNLFRVEGSFDSCFPDSLTLEDGDLVQFVQEGENGQWLVKKLVSEKSEWVPSSILQPAEGDTNNIIKNSNADMYNDSCSTASVESDTKESEVAKSFPAEQRAGS", "length": 1120, "header": "tr|A0A8V0YNY6-1|A0A8V0YNZ2_CHICK Computationally mapped isoform of MCF.2 cell line derived transforming sequence-like 2 OS=Gallus gallus OX=9031 GN=MCF2L2 PE=3 SV=1 CANONICAL=A0A8V0YNZ2-1" }, "locus": { "chromosome": "9", "start_pos": 16066980, "end_pos": 15959847, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010039382.1", "url": "https://www.ensembl.org/id/ENSGALT00010039382.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010022715.1", "url": "https://www.ensembl.org/id/ENSGALP00010022715.1" } ] } }, { "isoform_ac": "A0A8V0YNZ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNZ2/entry#A0A8V0YNZ2-1", "sequence": { "sequence": "MASRCRKCGQQVPRNLPFTAVRITEGEMKSYHDFIGGCIRLECMAKKDEIMQQEIRPLVAVDIIEQLHRQFAILSGGRGKDGAPIITFPEFAGFSEIPDEDFLNVVTYLTSIPSLEAASIGFIIIIDRRRDKWSAVKASLTRIAGAFPGNLQLVFVLRPSRFIQRAIADIGIKLYRDDFKMKVPIIMLNSVSDLHGYIDKCQLTRELGGTLEYGHSQWIHHRTAIENFAMTVKTTAQMLQTFGTDLAETELPNDVQCTEELLSAHTDHHSKLKDELKLAVKQGATLLTCIREPVTRSANSKLSPDELENVATVERLLAQLDETEKAFDQFWTKHHLKLEQCLQLRHFEHDFREVKLTLDNLMEAQAGFSDVGDSVTRVEHLLREQKQLEEKGQEPLEKAQTLALHGEQLIQNNHYAVDSIRPKCVELRRICDDFTNETKKKYDILGKSLELHKQLDKASQWCEAGIYLLASQAVDKCQSQEGAETALVEIEKFLATAKEHQLSNPKEFYNQFDTILTPEIKANAQRILQKLEDVQEMFDKRQVSLKKLAAKQTRPVQPVAPHPESSPKRASPKTTRPAGVATNRRSAEITCPPKSISEAELSKKKSIKKTKGGIKIEVMHEASQGGSSRVLVMSESDENLSTRRSHIINELIETERVYVEELQSIIEGYASEMDNPSLLHLIPSVLQNKKDILFGNLPEIYEFHNRIFLKELENCIENPELLARCFLKRKEDLQIYEKYCQNKPRSEALWRQCGDSIFFQECQRKLDHKLSLDAYLLKPVQRITKYQLLLKEMLKCSKNSEGTAELEEALATVLDIIKSVNDSMHQIAITGYEGDVSELGKLLMQGSFNVWTDHKKGHNKVKDLARFKPMQRHLFLYTKMLLFCKKREENTDGHEKTASYSFKNSLKMSTVGITENVKGDNKKFEIWYNGREEVYIIQASSVELKNTWISEIRKVLTGQLEACREASQLHQRITESVYHAPMNSSNITRYSRKSSSIYENKSETSNVEASNNKNRNSSPSARQKRVDASTSLNLERTALARKRFTLQGLSNRRAPPKDPESKEREVARRFSLASSISTTVNASAVTKGPLVPAVKVKRHEIKSDPTPLGFEDAFENTILAQTKCSTGSTTRPVPRSASQTGWPSRQMPSLDTFEDFEAIPSSMDELSNSSDMEEETNPNNGTNLFRVEGSFDSCFPDSLTLEDGDLVQFVQEGENGQWLVKKLVSEKSEWVPSSILQPAEGDTNNIIKNSNADMYNDSCSTASVESDTKESEVAKSFPAEQRAGS", "length": 1285, "header": "tr|A0A8V0YNZ2-1|A0A8V0YNZ2_CHICK Isoform 1 of MCF.2 cell line derived transforming sequence-like 2 OS=Gallus gallus OX=9031 GN=MCF2L2 PE=3 SV=1 CANONICAL=A0A8V0YNZ2-1" }, "locus": { "chromosome": "9", "start_pos": 16066980, "end_pos": 15944702, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010039391.1", "url": "https://www.ensembl.org/id/ENSGALT00010039391.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010022720.1", "url": "https://www.ensembl.org/id/ENSGALP00010022720.1" } ] } }, { "isoform_ac": "A0A8V0YVH0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNZ2/entry#A0A8V0YVH0-1", "sequence": { "sequence": "MLCSSLCEMLFWLKEEEMSHQELTQRLTTVITHVDEIMQQEIRPLVAVDIIEQLHRQFAILSGGRGKDGAPIITFPEFAGFSEIPDEDFLNVVTYLTSIPSLEAASIGFIIIIDRRRDKWSAVKASLTRIAGAFPGNLQLVFVLRPSRFIQRAIADIGIKLYRDDFKMKVPIIMLNSVSDLHGYIDKCQLTRELGGTLEYGHSQWIHHRTAIENFAMTVKTTAQMLQTFGTDLAETELPNDVQCTEELLSAHTDHHSKLKDELKLAVKQGATLLTCIREPVTRSANSKLSPDELENVATVERLLAQLDETEKAFDQFWTKHHLKLEQCLQLRHFEHDFREVKLTLDNLMEAQAGFSDVGDSVTRVEHLLREQKQLEEKGQEPLEKAQTLALHGEQLIQNNHYAVDSIRPKCVELRRICDDFTNETKKKYDILGKSLELHKQLDKASQWCEAGIYLLASQAVDKCQSQEGAETALVEIEKFLATAKEHQLSNPKEFYNQFDTILTPEIKANAQRILQKLEDVQEMFDKRQVSLKKLAAKQTRPVQPVAPHPESSPKRASPKTTRPAGVATNRRSAEITCPPKSISEAELSKKKSIKKTKGGIKIEVMHEASQGGSSRVLVMSESDENLSTRRSHIINELIETERVYVEELQSIIEGYASEMDNPSLLHLIPSVLQNKKDILFGNLPEIYEFHNRIFLKELENCIENPELLARCFLKRKEDLQIYEKYCQNKPRSEALWRQCGDSIFFQECQRKLDHKLSLDAYLLKPVQRITKYQLLLKEMLKCSKNSEGTAELEEALATVLDIIKSVNDSMHQIAITGYEGDVSELGKLLMQGSFNVWTDHKKGHNKVKDLARFKPMQRHLFLYTKMLLFCKKREENTDGHEKTASYSFKNSLKMSTVGITENVKGDNKKFEIWYNGREEVYIIQASSVELKNTWISEIRKVLTGQLEACREASQLHQRITESVYHAPMNSSNITRYSRKSSSIYENKSETSNVEASNNKNRNSSPSARQKRDPESKEREVARRFSLASSISTTVNASAVTKGWPSRQMPSLDTFEDFEAIPSSMDELSNSSDMEEETNPNNGTNLFRVEGSFDSCFPDSLTLEDGDLVQFVQEGENGQWLVKKLVSEKSEWVPSSILQPAEGDTNNIIKNSNADMYNDSCSTASVESDTKESEVAKSFPAEQRAGS", "length": 1187, "header": "tr|A0A8V0YVH0-1|A0A8V0YVH0_CHICK Computationally mapped isoform of MCF.2 cell line derived transforming sequence-like 2 OS=Gallus gallus OX=9031 GN=MCF2L2 PE=3 SV=1 CANONICAL=A0A8V0YNZ2-1" }, "locus": { "chromosome": "9", "start_pos": 16066980, "end_pos": 15923580, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010039427.1", "url": "https://www.ensembl.org/id/ENSGALT00010039427.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010022747.1", "url": "https://www.ensembl.org/id/ENSGALP00010022747.1" } ] } }, { "isoform_ac": "A0A8V0YVI0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNZ2/entry#A0A8V0YVI0-1", "sequence": { "sequence": "MIQYIALLCQQTGDEIMQQEIRPLVAVDIIEQLHRQFAILSGGRGKDGAPIITFPEFAGFSEIPDEDFLNVVTYLTSIPSLEAASIGFIIIIDRRRDKWSAVKASLTRIAGAFPGNLQLVFVLRPSRFIQRAIADIGIKLYRDDFKMKVPIIMLNSVSDLHGYIDKCQLTRELGGTLEYGHSQWIHHRTAIENFAMTVKTTAQMLQTFGTDLAETELPNDVQCTEELLSAHTDHHSKLKDELKLAVKQGATLLTCIREPVTRSANSKLSPDELENVATVERLLAQLDETEKAFDQFWTKHHLKLEQCLQLRHFEHDFREVKLTLDNLMEAQAGFSDVGDSVTRVEHLLREQKQLEEKGQEPLEKAQTLALHGEQLIQNNHYAVDSIRPKCVELRRICDDFTNETKKKYDILGKSLELHKQLDKASQWCEAGIYLLASQAVDKCQSQEGAETALVEIEKFLATAKEHQLSNPKEFYNQFDTILTPEIKANAQRILQKLEDVQEMFDKRQVSLKKLAAKQTRPVQPVAPHPESSPKRASPKTTRPAGVATNRRSAEITCPPKSISEAELSKKKSIKKTKGGIKIEVMHEASQGGSSRVLVMSESDENLSTRRSHIINELIETERVYVEELQSIIEGYASEMDNPSLLHLIPSVLQNKKDILFGNLPEIYEFHNRIFLKELENCIENPELLARCFLKRKEDLQIYEKYCQNKPRSEALWRQCGDSIFFQECQRKLDHKLSLDAYLLKPVQRITKYQLLLKEMLKCSKNSEGTAELEEALATVLDIIKSVNDSMHQIAITGYEGDVSELGKLLMQGSFNVWTDHKKGHNKVKDLARFKPMQRHLFLYTKMLLFCKKREENTDGHEKTASYSFKNSLKMSTVGITENVKGDNKKFEIWYNGREEVYIIQASSVELKNTWISEIRKVLTGQLEACREASQLHQRITESVYHAPMNSSNITRYSRKSSSIYENKSETSNVEASNNKNRNSSPSARQKRGWPSRQMPSLDTFEDFEAIPSSMDELSNSSDMEEETNPNNGTNLFRVEGSFDSCFPDSLTLEDGDLVQFVQEGENGQWLVKKLVSEKSEWVPSSILQPAEGDTNNIIKNSNADMYNDSCSTASVESDTKESEVAKSFPAEQRAGS", "length": 1136, "header": "tr|A0A8V0YVI0-1|A0A8V0YVI0_CHICK Computationally mapped isoform of MCF.2 cell line derived transforming sequence-like 2 OS=Gallus gallus OX=9031 GN=MCF2L2 PE=3 SV=1 CANONICAL=A0A8V0YNZ2-1" }, "locus": { "chromosome": "9", "start_pos": 16066980, "end_pos": 15918609, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010039442.1", "url": "https://www.ensembl.org/id/ENSGALT00010039442.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010022757.1", "url": "https://www.ensembl.org/id/ENSGALP00010022757.1" } ] } }, { "isoform_ac": "A0A8V0YXD9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNZ2/entry#A0A8V0YXD9-1", "sequence": { "sequence": "MASRCRKCGQQVPRNLPFTAVRITEGEMKSYHDFIGGCIRLECMAKKDEIMQQEIRPLVAVDIIEQLHRQFAILSGGRGKDGAPIITFPEFAGFSEIPDEDFLNVVTYLTSIPSLEAASIGFIIIIDRRRDKWSAVKASLTRIAGAFPGNLQLVFVLRPSRFIQRAIADIGIKLYRDDFKMKVPIIMLNSVSDLHGYIDKCQLTRELGGTLEYGHSQWIHHRTAIENFAMTVKTTAQMLQTFGTDLAETELPNDVQCTEELLSAHTDHHSKLKDELKLAVKQGATLLTCIREPVTRSANSKLSPDELENVATVERLLAQLDETEKAFDQFWTKHHLKLEQCLQLRHFEHDFREVKLTLDNLMEAQAGFSDVGDSVTRVEHLLREQKQLEEKGQEPLEKAQTLALHGEQLIQNNHYAVDSIRPKCVELRRICDDFTNETKKKYDILGKSLELHKQLDKASQWCEAGIYLLASQAVDKCQSQEGAETALVEIEKFLATAKEHQLSNPKEFYNQFDTILTPEIKANAQRILQKLEDVQEMFDKRQVSLKKLAAKQTRPVQPVAPHPESSPKRASPKTTRPAGVATNRRSAEITCPPKSISEAELSKKKSIKKTKGGIKIEVMHEASQGGSSRVLVMSESDENLSTRRSHIINELIETERVYVEELQSIIEGYASEMDNPSLLHLIPSVLQNKKDILFGNLPEIYEFHNRIFLKELENCIENPELLARCFLKRKEDLQIYEKYCQNKPRSEALWRQCGDSIFFQECQRKLDHKLSLDAYLLKPVQRITKYQLLLKEMLKCSKNSEGTAELEEALATVLDIIKSVNDSMHQIAITGYEGDVSELGKLLMQGSFNVWTDHKKGHNKVKDLARFKPMQRHLFLYTKMLLFCKKREENTDGHEKTASYSFKNSLKMSTVGITENVKGDNKKFEIWYNGREEVYIIQASSVELKNTWISEIRKVLTGQLEACREASQLHQRITESVYHAPMNSSNITRYSRKSSSIYENKSETSNVEASNNKNRNSSPSARQKRDPESKEREVARRFSLASSISTTVNASAVTKGPLVPAVKVKRHEIKSDPTPLGFEDAFENTILAQTKCSTGSTTRPVPRSASQTGWPSRQMPSLDTFEDFEAIPSSMDELSNSSDMEEETNPNNGTNLFRVEGSFDSCFPDSLTLEDGDLVQFVQEGENGQWLVKKLVSEKSEWVPSSILQPAEGDTNNIIKNSNADMYNDSCSTASVESDTKESEVAKSFPAEQRAGS", "length": 1253, "header": "tr|A0A8V0YXD9-1|A0A8V0YXD9_CHICK Computationally mapped isoform of MCF.2 cell line derived transforming sequence-like 2 OS=Gallus gallus OX=9031 GN=MCF2L2 PE=3 SV=1 CANONICAL=A0A8V0YNZ2-1" }, "locus": { "chromosome": "9", "start_pos": 16066980, "end_pos": 15944702, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010039395.1", "url": "https://www.ensembl.org/id/ENSGALT00010039395.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010022723.1", "url": "https://www.ensembl.org/id/ENSGALP00010022723.1" } ] } }, { "isoform_ac": "A0A8V0YXE4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNZ2/entry#A0A8V0YXE4-1", "sequence": { "sequence": "MDEIMQQEIRPLVAVDIIEQLHRQFAILSGGRGKDGAPIITFPEFAGFSEIPDEDFLNVVTYLTSIPSLEAASIGFIIIIDRRRDKWSAVKASLTRIAGAFPGNLQLVFVLRPSRFIQRAIADIGIKLYRDDFKMKIIMLNSVSDLHGYIDKCQLTRELGGTLEYGHSQWIHHRTAIENFAMTVKTTAQMLQTFGTDLAETELPNDVQCTEELLSAHTDHHSKLKDELKLAVKQGATLLTCIREPVTRSANSKLSPDELENVATVERLLAQLDETEKAFDQFWTKHHLKLEQCLQLRHFEHDFREVKLTLDNLMEAQAGFSDVGDSVTRVEHLLREQKQLEEKGQEPLEKAQTLALHGEQLIQNNHYAVDSIRPKCVELRRICDDFTNETKKKYDILGKSLELHKQLDKASQWCEAGIYLLASQAVDKCQSQEGAETALVEIEKFLATAKEHQLSNPKEFYNQFDTILTPEIKANAQRILQKLEDVQEMFDKRQVSLKKLAAKQTRPVQPVAPHPESSPKRASPKTTRPAGVATNRRSAEITCPPKSISEAELSKKKSIKKTKGGIKIEVMHEASQGGSSRVLVMSESDENLSTRRSHIINELIETERVYVEELQSIIEGYASEMDNPSLLHLIPSVLQNKKDILFGNLPEIYEFHNRIFLKELENCIENPELLARCFLKRKEDLQIYEKYCQNKPRSEALWRQCGDSIFFQECQRKLDHKLSLDAYLLKPVQRITKYQLLLKEMLKCSKNSEGTAELEEALATVLDIIKSVNDSMHQIAITGYEGDVSELGKLLMQGSFNVWTDHKKGHNKVKDLARFKPMQRHLFLYTKMLLFCKKREENTDGHEKTASYSFKNSLKMSTVGITENVKGDNKKFEIWYNGREEVYIIQASSVELKNTWISEIRKVLTGQLEACREASQLHQRITESVYHAPMNSSNITRYSRKSSSIYENKSETSNVEASNNKNRNSSPSARQKRGWPSRQMPSLDTFEDFEAIPSSMDELSNSSDMEEETNPNNGTNLFRVEGSFDSCFPDSLTLEDGDLVQFVQEGENGQWLVKKLVSEKSEWVPSSILQPAEGDTNNIIKNSNADMYNDSCSTASVESDTKESEVAKSFPAEQRAGS", "length": 1122, "header": "tr|A0A8V0YXE4-1|A0A8V0YXE4_CHICK Computationally mapped isoform of MCF.2 cell line derived transforming sequence-like 2 OS=Gallus gallus OX=9031 GN=MCF2L2 PE=3 SV=1 CANONICAL=A0A8V0YNZ2-1" }, "locus": { "chromosome": "9", "start_pos": 16066980, "end_pos": 15936441, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010039402.1", "url": "https://www.ensembl.org/id/ENSGALT00010039402.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010022728.1", "url": "https://www.ensembl.org/id/ENSGALP00010022728.1" } ] } }, { "isoform_ac": "A0A8V0YXG9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNZ2/entry#A0A8V0YXG9-1", "sequence": { "sequence": "MIQYIALLCQQTGDEIMQQEIRPLVAVDIIEQLHRQFAILSGGRGKDGAPIITFPEFAGFSEIPDEDFLNVVTYLTSIPSLEAASIGFIIIIDRRRDKWSAVKASLTRIAGAFPGNLQLVFVLRPSRFIQRAIADIGIKLYRDDFKMKIIMLNSVSDLHGYIDKCQLTRELGGTLEYGHSQWIHHRTAIENFAMTVKTTAQMLQTFGTDLAETELPNDVQCTEELLSAHTDHHSKLKDELKLAVKQGATLLTCIREPVTRSANSKLSPDELENVATVERLLAQLDETEKAFDQFWTKHHLKLEQCLQLRHFEHDFREVKLTLDNLMEAQAGFSDVGDSVTRVEHLLREQKQLEEKGQEPLEKAQTLALHGEQLIQNNHYAVDSIRPKCVELRRICDDFTNETKKKYDILGKSLELHKQLDKASQWCEAGIYLLASQAVDKCQSQEGAETALVEIEKFLATAKEHQLSNPKEFYNQFDTILTPEIKANAQRILQKLEDVQEMFDKRQVSLKKLAAKQTRPVQPVAPHPESSPKRASPKTTRPAGVATNRRSAEITCPPKSISEAELSKKKSIKKTKGGIKIEVMHEASQGGSSRVLVMSESDENLSTRRSHIINELIETERVYVEELQSIIEGYASEMDNPSLLHLIPSVLQNKKDILFGNLPEIYEFHNRIFLKELENCIENPELLARCFLKRKEDLQIYEKYCQNKPRSEALWRQCGDSIFFQECQRKLDHKLSLDAYLLKPVQRITKYQLLLKEMLKCSKNSEGTAELEEALATVLDIIKSVNDSMHQIAITGYEGDVSELGKLLMQGSFNVWTDHKKGHNKVKDLARFKPMQRHLFLYTKMLLFCKKREENTDGHEKTASYSFKNSLKMSTVGITENVKGDNKKFEIWYNGREEVYIIQASSVELKNTWISEIRKVLTGQLEACREASQLHQRITESVYHAPMNSSNITRYSRKSSSIYENKSETSNVEASNNKNRNSSPSARQKRGWPSRQMPSLDTFEDFEAIPSSMDELSNSSDMEEETNPNNGTNLFRVEGSFDSCFPDSLTLEDGDLVQFVQEGENGQWLVKKLVSEKSEWVPSSILQPAEGDTNNIIKNSNADMYNDSCSTASVESDTKESEVAKSFPAEQRAGS", "length": 1134, "header": "tr|A0A8V0YXG9-1|A0A8V0YXG9_CHICK Computationally mapped isoform of MCF.2 cell line derived transforming sequence-like 2 OS=Gallus gallus OX=9031 GN=MCF2L2 PE=3 SV=1 CANONICAL=A0A8V0YNZ2-1" }, "locus": { "chromosome": "9", "start_pos": 16066980, "end_pos": 15918609, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010039437.1", "url": "https://www.ensembl.org/id/ENSGALT00010039437.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010022753.1", "url": "https://www.ensembl.org/id/ENSGALP00010022753.1" } ] } }, { "isoform_ac": "A0A8V0Z291-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNZ2/entry#A0A8V0Z291-1", "sequence": { "sequence": "MLCSSLCEMLFWLKEEEMSHQELTQRLTTVITHVDEIMQQEIRPLVAVDIIEQLHRQFAILSGGRGKDGAPIITFPEFAGFSEIPDEDFLNVVTYLTSIPSLEAASIGFIIIIDRRRDKWSAVKASLTRIAGAFPGNLQLVFVLRPSRFIQRAIADIGIKLYRDDFKMKVPIIMLNSVSDLHGYIDKCQLTRELGGTLEYGHSQWIHHRTAIENFAMTVKTTAQMLQTFGTDLAETELPNDVQCTEELLSAHTDHHSKLKDELKLAVKQGATLLTCIREPVTRSANSKLSPDELENVATVERLLAQLDETEKAFDQFWTKHHLKLEQCLQLRHFEHDFREVKLTLDNLMEAQAGFSDVGDSVTRVEHLLREQKQLEEKGQEPLEKAQTLALHGEQLIQNNHYAVDSIRPKCVELRRICDDFTNETKKKYDILGKSLELHKQLDKASQWCEAGIYLLASQAVDKCQSQEGAETALVEIEKFLATAKEHQLSNPKEFYNQFDTILTPEIKANAQRILQKLEDVQEMFDKRQVSLKKLAAKQTRPVQPVAPHPESSPKRASPKTTRPAGVATNRRSAEITCPPKSISEAELSKKKSIKKTKGGIKIEVMHEASQGGSSRVLVMSESDENLSTRRSHIINELIETERVYVEELQSIIEGYASEMDNPSLLHLIPSVLQNKKDILFGNLPEIYEFHNRIFLKELENCIENPELLARCFLKRKEDLQIYEKYCQNKPRSEALWRQCGDSIFFQECQRKLDHKLSLDAYLLKPVQRITKYQLLLKEMLKCSKNSEGTAELEEALATVLDIIKSVNDSMHQIAITGYEGDVSELGKLLMQGSFNVWTDHKKGHNKVKDLARFKPMQRHLFLYTKMLLFCKKREENTDGHEKTASYSFKNSLKMSTVGITENVKGDNKKFEIWYNGREEVYIIQASSVELKNTWISEIRKVLTGQLEACREASQLHQRITESVYHAPMNSSNITRYSRKSSSIYENKSETSNVEASNNKNRNSSPSARQKRVDASTSLNLERTALARKRFTLQGLSNRRAPPKDPESKEREVARRFSLASSISTTVNASAVTKGPLVPAVKVKRHEIKSDPTPLGFEDAFENTILAQTKCSTGSTTRPVPRSASQTGWPSRQMPSLDTFEDFEAIPSSMDELSNSSDMEEETNPNNGTNLFRVEGSFDSCFPDSLTLEDGDLVQFVQEGENGQWLVKKLVSEKSEWVPSSILQPAEGDTNNIIKNSNADMYNDSCSTASVESDTKESEVAKSFPAEQRAGS", "length": 1272, "header": "tr|A0A8V0Z291-1|A0A8V0Z291_CHICK Computationally mapped isoform of MCF.2 cell line derived transforming sequence-like 2 OS=Gallus gallus OX=9031 GN=MCF2L2 PE=3 SV=1 CANONICAL=A0A8V0YNZ2-1" }, "locus": { "chromosome": "9", "start_pos": 16066980, "end_pos": 15923580, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010039413.1", "url": "https://www.ensembl.org/id/ENSGALT00010039413.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010022736.1", "url": "https://www.ensembl.org/id/ENSGALP00010022736.1" } ] } }, { "isoform_ac": "A0A8V0Z296-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNZ2/entry#A0A8V0Z296-1", "sequence": { "sequence": "MLCSSLCEMLFWLKEEEMSHQELTQRLTTVITHVDEIMQQEIRPLVAVDIIEQLHRQFAILSGGRGKDGAPIITFPEFAGFSEIPDEDFLNVVTYLTSIPSLEAASIGFIIIIDRRRDKWSAVKASLTRIAGAFPGNLQLVFVLRPSRFIQRAIADIGIKLYRDDFKMKVPIIMLNSVSDLHGYIDKCQLTRELGGTLEYGHSQWIHHRTAIENFAMTVKTTAQMLQTFGTDLAETELPNDVQCTEELLSAHTDHHSKLKDELKLAVKQGATLLTCIREPVTRSANSKLSPDELENVATVERLLAQLDETEKAFDQFWTKHHLKLEQCLQLRHFEHDFREVKLTLDNLMEAQAGFSDVGDSVTRVEHLLREQKQLEEKGQEPLEKAQTLALHGEQLIQNNHYAVDSIRPKCVELRRICDDFTNETKKKYDILGKSLELHKQLDKASQWCEAGIYLLASQAVDKCQSQEGAETALVEIEKFLATAKEHQLSNPKEFYNQFDTILTPEIKANAQRILQKLEDVQEMFDKRQVSLKKLAAKQTRPVQPVAPHPESSPKRASPKTTRPAGVATNRRSAEITCPPKSISEAELSKKKSIKKTKGGIKIEVMHEASQGGSSRVLVMSESDENLSTRRSHIINELIETERVYVEELQSIIEGYASEMDNPSLLHLIPSVLQNKKDILFGNLPEIYEFHNRIFLKELENCIENPELLARCFLKRKEDLQIYEKYCQNKPRSEALWRQCGDSIFFQECQRKLDHKLSLDAYLLKPVQRITKYQLLLKEMLKCSKNSEGTAELEEALATVLDIIKSVNDSMHQIAITGYEGDVSELGKLLMQGSFNVWTDHKKGHNKVKDLARFKPMQRHLFLYTKMLLFCKKREENTDGHEKTASYSFKNSLKMSTVGITENVKGDNKKFEIWYNGREEVYIIQASSVELKNTWISEIRKVLTGQLEACREASQLHQRITESVYHAPMNSSNITRYSRKSSSIYENKSETSNVEASNNKNRNSSPSARQKRDPESKEREVARRFSLASSISTTVNASAVTKGPLVPAVKVKRHEIKSDPTPLGFEGWPSRQMPSLDTFEDFEAIPSSMDELSNSSDMEEETNPNNGTNLFRVEGSFDSCFPDSLTLEDGDLVQFVQEGENGQWLVKKLVSEKSEWVPSSILQPAEGDTNNIIKNSNADMYNDSCSTASVESDTKESEVAKSFPAEQRAGS", "length": 1211, "header": "tr|A0A8V0Z296-1|A0A8V0Z296_CHICK Computationally mapped isoform of MCF.2 cell line derived transforming sequence-like 2 OS=Gallus gallus OX=9031 GN=MCF2L2 PE=3 SV=1 CANONICAL=A0A8V0YNZ2-1" }, "locus": { "chromosome": "9", "start_pos": 16066980, "end_pos": 15923580, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010039421.1", "url": "https://www.ensembl.org/id/ENSGALT00010039421.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010022741.1", "url": "https://www.ensembl.org/id/ENSGALP00010022741.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:424959", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424959", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A286ZLD6-1", "protein_name": "MCF.2 cell line derived transforming sequence-like 2", "gene_name": "MCF2L2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MLFWLKEEMAPQEFTRRLATVITHVDEIMQQEIRPLVAVDIIEQLHRQFAILSGGRGKDGAPIITFPEFVGFKHIPEEDFLNVMTYLTSVPSVEAASIGFVIIIDRRRDKWSSVKASLTRIAVAFPGNLQLIFILRPSRFIQRTFTDIGIKYYRDEFKMKVPIVMLNSVSDLHGYIDKSQLTEDLGGTLEYRHSQWINHRTAIENFALALKTTAQMLRTFGDCLATTELPRSVPSTEDLLMSHTKQRDKMQDELKLLGKQGATLLSCIREPATKSPTSKLNLNELDNVATMKRLLVQLDETEKAFSQFWSEHHLKLNQCLQLQHFEQNFCEVKLALGNLLAEQAECTDIGDSVTRVEQLLKEHKKLEGEGQEPLEKAQLLAVIGDQLIQNHHYAVDSIRPRCAELRHLCDDFINENKKKCDILEKSLELHRQLDKVSQWCEAGIYLLASQAVDKCHSREGVDIALNDIETFLGTVKEYQLPSPKEFYNQFELMLTLDVKVKAQKVLQKLSDVQEIFHKRQMSLMKLAARQTRPVQPVAPHPESSPKWVSPKISQPSTLAPCQKTLEEPYVETDLNSLEKEDDETKFEVKNEEIPESSHDGENPEPEQLEGSKNLSPSRRIIRDLLETEETYIKEIKNIIDGYILPMDFIWLKHLIPDVLQNNKDFLFGNIRELYEFHNRIFLKELEKCTENPELLARCFLKRKEDLQMYFKYHKNLPRARAIWQECQDCTYFGVCQRQLGHSLPLFKYLRGPSQRLIKYQMLLKGLLDFESPADLEVDPGELEGCSAKNGPKRMKDSAFSAELQQALAMMEDLIKSCELAVDLAAVTGCPDDIRKLGKVLMYGSFNVWAVHKDRYKMKDLIRFKPSQRQIYLFERGIVFCKIRMEPSDQGLSPHYIFKKSLKLMSLSIHQLGRGSSRKFEIANQNGLEKYILQAASKEIRDCWFSEISKLLMEQQNNTKDVYEDEDNGRQISSKSLGTFPFGRQL", "length": 985 }, "evidence": [ { "id": "A0A8V0YNZ2", "url": "https://omabrowser.org/oma/group/A0A8V0YNZ2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1MQ44-1", "protein_name": "MCF.2 cell line derived transforming sequence-like 2", "gene_name": "MCF2L2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MLFWLKEEMAPQEFTRRLATVITHVDEIMQQEIRPLVAVDIIEQLHRQFAILSGGRGKDGAPIITFPEFVGFKHIPDEDFLNVMTYLTSVPSMEAASIGFVIVIDRRRDKWSSIKASLTRIAVAFPGNLQLILILRPSRFIQRTFTDIGIKYYRDEFKMKVPIVMLNSVSDLHDYIDKSQLTADLGGTLEYRHSQWINHRTAIENFALALKTTAQMLQTFGACLATTELPRSIPSTEDLLMSHMRQWNKLQDELKLLGKQGATLLSCMQEPATKSPTSKLSLHEVENVATMERLLVQLDETQKAFIQFWSEHHLKLNQYLQLQHFEHSFCEVKLALDNLLAEQAEFSDIGDSVMHVEQLLKEHKKLEGEGQESLEKAQLLAVIGDQLIQSHHYAVDSIRPRCAELRHLCDDFINENKKKHDILEKSLELHRRLDKVSQWCEAGVYLLASQAVDKYQSREGIDIALNDIETFLGTAKEYQLPSSKDFYNQYELMLTLDIKTKAQKVLQKLSDVQEIFHKRQMSLMKLAARQTRPVQPVAPHPESSPKWASPKISQPSTLVPHQKTSEEPYTETDLNSEEKEDDETKSEVKNEEILESSHDADNPEPEQPDGSKNLSHSRHIIRDLVETEVTYIKEIKNIIDGYIIPMDFIWLKHLIPDVLRNNKEFLFGNIRELYEFHSRTFLKELEKCTENPELLARCFLKRKEDLQIYFKYHKNLPRARAIWQECQDCTYFGVCQRQLGHSLPLFKCLREPSQRLIKYQMLLKGLLDFESPEDLEMDPSDLEGGSAKNGPKRTKDSTFLADLQQALAMMEDLIKSCELAMDLAAVTGCPDDIGKFGKLLMHGSFNVWTVHKDRYKMKDLIRFKPSQRQIYLFEREIMFCKIQLEPSDQGLSPHYSFKKSMKLMTLSIRQLGRGSNRKFEIANQNGLEKYILQAASKEIRDCWFSEISKLLMKQQNNIKDVYEDEDNGRQISLKRCSSREFISMETSVNCEGAEDLEKENSVLSLSGLFRLDDSYETSTSGQEKGESIRGEKKGCQKKDTATNKTEESLETSTGLLAPAGKASFPRAEAVRAEAVRAQEGSLRPPSAEN", "length": 1089 }, "evidence": [ { "id": "A0A8V0YNZ2", "url": "https://omabrowser.org/oma/group/A0A8V0YNZ2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q86YR7-1", "protein_name": "Probable guanine nucleotide exchange factor MCF2L2", "gene_name": "MCF2L2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLSCLKEEMPPQELTRRLATVITHVDEIMQQEVRPLMAVEIIEQLHRQFAILSGGRGEDGAPIITFPEFSGFKHIPDEDFLNVMTYLTSIPSVEAASIGFIVVIDRRRDKWSSVKASLTRIAVAFPGNLQLIFILRPSRFIQRTFTDIGIKYYRNEFKTKVPIIMVNSVSDLHGYIDKSQLTRELGGTLEYRHGQWVNHRTAIENFALTLKTTAQMLQTFGSCLATAELPRSMLSTEDLLMSHTRQRDKLQDELKLLGKQGTTLLSCIQEPATKCPNSKLNLNQLENVTTMERLLVQLDETEKAFSHFWSEHHLKLNQCLQLQHFEHDFCKAKLALDNLLEEQAEFTGIGDSVMHVEQILKEHKKLEEKSQEPLEKAQLLALVGDQLIQSHHYAADAIRPRCVELRHLCDDFINGNKKKWDILGKSLEFHRQLDKVSQWCEAGIYLLASQAVDKCQSREGVDIALNDIATFLGTVKEYPLLSPKEFYNEFELLLTLDAKAKAQKVLQRLDDVQEIFHKRQVSLMKLAAKQTRPVQPVAPHPESSPKWVSSKTSQPSTSVPLARPLRTSEEPYTETELNSRGKEDDETKFEVKSEEIFESHHERGNPELEQQARLGDLSPRRRIIRDLLETEEIYIKEIKSIIDGYITPMDFIWLKHLIPDVLQNNKDFLFGNIRELYEFHNRTFLKELEKCAENPELLAHCFLKRKEDLQIYFKYHKNLPRARAIWQECQDCAYFGVCQRQLDHNLPLFKYLKGPSQRLIKYQMLLKGLLDFESPEDMEIDPGELGGSAKDGPKRTKDSAFSTELQQALAVIEDLIKSCELAVDLAAVTECPDDIGKLGKLLLHGPFSVWTIHKDRYKMKDLIRFKPSQRQIYLFERGIVFCKIRMEPGDQGLSPHYSFKKTMKLMTLSIRQLGRGSHRKFEIASRNGLEKYILQAASKEIRDCWFSEISKLLMEQQNNIKDQGNPQFEMSTSKGSGAGSGPWIKNMERATTSKEDPASSTGGIKGCSSREFSSMDTFEDCEGAEDMEKESSALSLAGLFQSDDSHETCSSKSAFLERGESSQGEKEERDEEETATRSTEEERAGASTGRLAPAGATAGFQARALRPRTSAQES", "length": 1114 }, "evidence": [ { "id": "A0A8V0YNZ2", "url": "https://omabrowser.org/oma/group/A0A8V0YNZ2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNZ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNZ2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "intracellular signal transduction", "id": "GO:0035556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035556", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNZ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNZ2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "guanyl-nucleotide exchange factor activity", "id": "GO:0005085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005085", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNZ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNZ2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1000, "end_pos": 1002, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1016, "end_pos": 1018, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1081, "end_pos": 1083, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1168, "end_pos": 1170, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1180, "end_pos": 1182, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1256, "end_pos": 1258, "annotation": "n_glycosylation_sequon" }, { "start_pos": 436, "end_pos": 438, "annotation": "n_glycosylation_sequon" }, { "start_pos": 639, "end_pos": 641, "annotation": "n_glycosylation_sequon" }, { "start_pos": 821, "end_pos": 823, "annotation": "n_glycosylation_sequon" }, { "start_pos": 983, "end_pos": 985, "annotation": 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TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export to the cytoplasm via the TAP/NXF1 pathway.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNZ7#function" }, { "database": "UniProtKB", "id": "ARBA00060265", "url": "https://www.uniprot.org/uniprotkb/ARBA00060265#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YNZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNZ7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "THOC3", "url": 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"A0A8V0YP00_CHICK", "mass": { "chemical_mass": 59751.0, "monoisotopic_mass": 59751.0 }, "refseq": {}, "gene_names": [ { "name": "NUP62", "type": "recommended", "evidence": [ { "id": "A0A8V0YP00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP00" } ] } ], "protein_names": [ { "name": "Nuclear pore glycoprotein p62", "type": "recommended", "evidence": [ { "id": "A0A8V0YP00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP00/entry#names_and_taxonomy" } ] }, { "name": "62 kDa nucleoporin", "type": "synonym", "evidence": [ { "id": "A0A8V0YP00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP00/entry#names_and_taxonomy" } ] }, { "name": "Nucleoporin Nup62", "type": "synonym", "evidence": [ { "id": "A0A8V0YP00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP00/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Essential component of the nuclear pore complex. The N-terminal is probably involved in nucleocytoplasmic transport. The C-terminal is involved in protein-protein interaction probably via coiled-coil formation, promotes its association with centrosomes and may function in anchorage of p62 to the pore complex. Plays a role in mitotic cell cycle progression by regulating centrosome segregation, centriole maturation and spindle orientation. It might be involved in protein recruitment to the centrosome after nuclear breakdown.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YP00", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP00#function" }, { "database": "UniProtKB", "id": "ARBA00056849", "url": "https://www.uniprot.org/uniprotkb/ARBA00056849#function" }, { "database": "UniProtKB", "id": "A0A8V0Z269", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z269#function" }, { "database": "UniProtKB", "id": "A0A8V0Z274", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z274#function" }, { "database": "UniProtKB", "id": "A0A8V0YVR8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YVR8#function" }, { "database": "UniProtKB", "id": "A0A8V0YVS2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YVS2#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YP00", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP00" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "NUP62", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP00", "locus": { "chromosome": "4", "start_pos": 1852505, "end_pos": 1861344, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010016362", "url": "https://www.ensembl.org/id/ENSGALG00010016362" } ] } } ], "crossref": [ { "id": "A0A8V0YP00", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YP00", "database": "AlphaFoldDB", "categories": [] }, { "id": "422183", "url": "https://www.ncbi.nlm.nih.gov/gene/422183", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR007758", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007758", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR026010", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026010", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:422183", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422183", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "EMMSKQV", "url": "https://omabrowser.org/oma/group/EMMSKQV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YP00", "url": "https://www.orthodb.org/?gene=A0A8V0YP00", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YVR8", "url": "https://www.orthodb.org/?gene=A0A8V0YVR8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YVS2", "url": "https://www.orthodb.org/?gene=A0A8V0YVS2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z269", "url": "https://www.orthodb.org/?gene=A0A8V0Z269", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z274", "url": "https://www.orthodb.org/?gene=A0A8V0Z274", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12084", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12084", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12084:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12084:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05064", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05064", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-159227", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-159227", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-159230", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-159230", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-159231", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-159231", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-159236", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-159236", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-1855170", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1855170", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-1855196", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1855196", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-1855229", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1855229", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-191859", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-191859", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-3108214", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3108214", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-3232142", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3232142", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-3301854", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3301854", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-4085377", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-4085377", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-4551638", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-4551638", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-4615885", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-4615885", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YP00", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP00", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YP00-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP00-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YVR8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YVR8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YVR8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YVR8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YVS2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YVS2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YVS2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YVS2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z269", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z269", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z269-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z269-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z274", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z274", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z274-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z274-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSQFNFSSAPAGGGFSFSTPKTAASTTAATGFSFTPAPSSGFTFGGAAPTPASSQPVTPFSFSTPASSALPTAFSFGTPATATTAAPAASVFPLGGNAPKLNFGGTSTTQATGITGGFGFGTSAPTSVPSSQAAAPSGFMFGTAATTTTTTTAAQPGTTGGFTFSSGTTTQAGTTGFNIGATSTAAPQAAPTGLTFGAAPAAAATTTASLGSTTQPAATPFSLGGQSSGLNFGSLISTAATGAPTATLTASTSQGPTLSFGSKLGVTTTASTTTAASTAPLLGSTGPVLFASIASSSAPPSSTSTGLSLGAPSTGTTGLGTSGFGLKPPGTTAAATSTATSTSASSFALNLKPLTTTGTIGAVTSTAAITTTTPSAPPVMTYAQLESLINKWSLELEDQEKHFLHQATQVNAWDRTLIENGEKITSLHREVEKVKLDQKRLDQELDFILSQQKELEDLLTPLEESVKEQSGTIYLQHADEERERTYKLAENIDAQLKRMAQDLKDIIEHLNTSGRPADTSDPLQQICKILNAHMDSLQWIDQNSVRGLLWLLSCRKTLPTDGPNLLAAEEGGGGDEGLREPPQGAGAQLSDHL", "length": 593, "header": "tr|A0A8V0YP00-1|A0A8V0YP00_CHICK Isoform 1 of Nuclear pore glycoprotein p62 OS=Gallus gallus OX=9031 GN=NUP62 PE=1 SV=1 CANONICAL=A0A8V0YP00-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YP00-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP00/entry#A0A8V0YP00-1", "sequence": { "sequence": "MSQFNFSSAPAGGGFSFSTPKTAASTTAATGFSFTPAPSSGFTFGGAAPTPASSQPVTPFSFSTPASSALPTAFSFGTPATATTAAPAASVFPLGGNAPKLNFGGTSTTQATGITGGFGFGTSAPTSVPSSQAAAPSGFMFGTAATTTTTTTAAQPGTTGGFTFSSGTTTQAGTTGFNIGATSTAAPQAAPTGLTFGAAPAAAATTTASLGSTTQPAATPFSLGGQSSGLNFGSLISTAATGAPTATLTASTSQGPTLSFGSKLGVTTTASTTTAASTAPLLGSTGPVLFASIASSSAPPSSTSTGLSLGAPSTGTTGLGTSGFGLKPPGTTAAATSTATSTSASSFALNLKPLTTTGTIGAVTSTAAITTTTPSAPPVMTYAQLESLINKWSLELEDQEKHFLHQATQVNAWDRTLIENGEKITSLHREVEKVKLDQKRLDQELDFILSQQKELEDLLTPLEESVKEQSGTIYLQHADEERERTYKLAENIDAQLKRMAQDLKDIIEHLNTSGRPADTSDPLQQICKILNAHMDSLQWIDQNSVRGLLWLLSCRKTLPTDGPNLLAAEEGGGGDEGLREPPQGAGAQLSDHL", "length": 593, "header": "tr|A0A8V0YP00-1|A0A8V0YP00_CHICK Isoform 1 of Nuclear pore glycoprotein p62 OS=Gallus gallus OX=9031 GN=NUP62 PE=1 SV=1 CANONICAL=A0A8V0YP00-1" }, "locus": { "chromosome": "4", "start_pos": 1861195, "end_pos": 1853052, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010039398.1", "url": "https://www.ensembl.org/id/ENSGALT00010039398.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010022725.1", "url": "https://www.ensembl.org/id/ENSGALP00010022725.1" } ] } }, { "isoform_ac": "A0A8V0YVR8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP00/entry#A0A8V0YVR8-1", "sequence": { "sequence": "MSQFNFSSAPAGGGFSFSTPKTAASTTAATGFSFTPAPSSGFTFGGAAPTPASSQPVTPFSFSTPASSALPTAFSFGTPATATTAAPAASVFPLGGNAPKLNFGGTSTTQATGITGGFGFGTSAPTSVPSSQAAAPSGFMFGTAATTTTTTTAAQPGTTGGFTFSSGTTTQAGTTGFNIGATSTAAPQAAPTGLTFGAAPAAAATTTASLGSTTQPAATPFSLGGQSSGLNFGSLISTAATGAPTATLTASTSQGPTLSFGSKLGVTTTASTTTAASTAPLLGSTGPVLFASIASSSAPPSSTSTGLSLGAPSTGTTGLGTSGFGLKPPGTTAAATSTATSTSASSFALNLKPLTTTGTIGAVTSTAAITTTTPSAPPVMTYAQLESLINKWSLELEDQEKHFLHQATQVNAWDRTLIENGEKITSLHREVEKVKLDQKRLDQELDFILSQQKELEDLLTPLEESVKEQSGTIYLQHADEERERTYKLAENIDAQLKRMAQDLKDIIEHLNTSGRPADTSDPLQQICKILNAHMDSLQWIDQNSALLQRKVEEVTKVCESRRKEQERSFRITFD", "length": 574, "header": "tr|A0A8V0YVR8-1|A0A8V0YVR8_CHICK Computationally mapped isoform of Nuclear pore glycoprotein p62 OS=Gallus gallus OX=9031 GN=NUP62 PE=1 SV=1 CANONICAL=A0A8V0YP00-1" }, "locus": { "chromosome": "4", "start_pos": 1861195, "end_pos": 1853048, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010039390.1", "url": "https://www.ensembl.org/id/ENSGALT00010039390.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010022719.1", "url": "https://www.ensembl.org/id/ENSGALP00010022719.1" } ] } }, { "isoform_ac": "A0A8V0YVS2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP00/entry#A0A8V0YVS2-1", "sequence": { "sequence": "MSQFNFSSAPAGGGFSFSTPKTAASTTAATGFSFTPAPSSGFTFGGAAPTPASSQPVTPFSFSTPASSALPTAFSFGTPATATTAAPAASVFPLGGNAPKLNFGGTSTTQATGITGGFGFGTSAPTSVPSSQAAAPSGFMFGTAATTTTTTTAAQPGTTGGFTFSSGTTTQAGTTGFNIGATSTAAPQAAPTGLTFGAAPAAAATTTASLGSTTQPAATPFSLGGQSSAATGAPTATLTASTSQGPTLSFGSKLGVTTTASTTTAASTAPLLGSTGPVLFASIASSSAPPSSTSTGLSLGAPSTGTTGLGTSGFGLKPPGTTAAATSTATSTSASSFALNLKPLTTTGTIGAVTSTAAITTTTPSAPPVMTYAQLESLINKWSLELEDQEKHFLHQATQVNAWDRTLIENGEKITSLHREVEKVKLDQKRLDQELDFILSQQKELEDLLTPLEESVKEQSGTIYLQHADEERERTYKLAENIDAQLKRMAQDLKDIIEHLNTSGRPADTSDPLQQICKILNAHMDSLQWIDQNSALLQRKVEEVTKVCESRRKEQERSFRITFD", "length": 564, "header": "tr|A0A8V0YVS2-1|A0A8V0YVS2_CHICK Computationally mapped isoform of Nuclear pore glycoprotein p62 OS=Gallus gallus OX=9031 GN=NUP62 PE=1 SV=1 CANONICAL=A0A8V0YP00-1" }, "locus": { "chromosome": "4", "start_pos": 1861195, "end_pos": 1853048, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010039396.1", "url": "https://www.ensembl.org/id/ENSGALT00010039396.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010022724.1", "url": "https://www.ensembl.org/id/ENSGALP00010022724.1" } ] } }, { "isoform_ac": "A0A8V0Z269-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP00/entry#A0A8V0Z269-1", "sequence": { "sequence": "MSQFNFSSAPAGGGFSFSTPKTAASTTAATGFSFTPAPSSGFTFGGAAPTPASSQPVTPFSFSTPASSALPTAFSFGTPATATTAAPAASVFPLGGNAPKLNFGGTSTTQATGITGGFGFGTSAPTSVPSSQAAAPSGFMFGTAATTTTTTTAAQPGTTGGFTFSSGTTTQAGTTGFNIGATSTAAPQAAPTGLTFGAAPAAAATTTASLGSTTQPAATPFSLGGQSSGLNFGSLISTAATGAPTATLTASTSQGPTLSFGSKLGVTTTASTTTAASTAPLLGSTGPVLFASIASSSAPPSSTSTGLSLGAPSTGTTGLGTSGFGLKPPGTTAAATSTATSTSASSFALNLKPLTTTGTIGAVTSTAAITTTTPSAPPVMTYAQLESLINKWSLELEDQEKHFLHQATQVNAWDRTLIENGEKITSLHREVEKVKLDQKRLDQELDFILSQQKELEDLLTPLEESVKEQSGTIYLQHADEERERTYKLAENIDAQLKRMAQDLKDIIEHLNTSGRPADTSDPLQQICKILNAHMDSLQWIDQNSEDKCKRSHSRRAFIVKPGVAPLEC", "length": 568, "header": "tr|A0A8V0Z269-1|A0A8V0Z269_CHICK Computationally mapped isoform of Nuclear pore glycoprotein p62 OS=Gallus gallus OX=9031 GN=NUP62 PE=1 SV=1 CANONICAL=A0A8V0YP00-1" }, "locus": { "chromosome": "4", "start_pos": 1861195, "end_pos": 1854318, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010039386.1", "url": "https://www.ensembl.org/id/ENSGALT00010039386.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010022716.1", "url": "https://www.ensembl.org/id/ENSGALP00010022716.1" } ] } }, { "isoform_ac": "A0A8V0Z274-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP00/entry#A0A8V0Z274-1", "sequence": { "sequence": "MSQFNFSSAPAGGGFSFSTPKTAASTTAATGFSFTPAPSSGFTFGGAAPTPASSQPVTPFSFSTPASSALPTAFSFGTPATATTAAPAASVFPLGGNAPKLNFGGTSTTQATGITGGFGFGTSAPTSVPSSQAAAPSGFMFGTAATTTTTTTAAQPGTTGGFTFSSGTTTQAGTTGFNIGATSTAAPQAAPTGLTFGAAPAAAATTTASLGSTTQPAATPFSLGGQSSGLNFGSLISTAATGAPTATLTASTSQGPTLSFGSKLGVTTTASTTTAASTAPLLGSTGLSLGAPSTGTTGLGTSGFGLKPPGTTAAATSTATSTSASSFALNLKPLTTTGTIGAVTSTAAITTTTPSAPPVMTYAQLESLINKWSLELEDQEKHFLHQATQVNAWDRTLIENGEKITSLHREVEKVKLDQKRLDQELDFILSQQKELEDLLTPLEESVKEQSGTIYLQHADEERERTYKLAENIDAQLKRMAQDLKDIIEHLNTSGRPADTSDPLQQICKILNAHMDSLQWIDQNSALLQRKVEEVTKVCESRRKEQERSFRITFD", "length": 554, "header": "tr|A0A8V0Z274-1|A0A8V0Z274_CHICK Computationally mapped isoform of Nuclear pore glycoprotein p62 OS=Gallus gallus OX=9031 GN=NUP62 PE=1 SV=1 CANONICAL=A0A8V0YP00-1" }, "locus": { "chromosome": "4", "start_pos": 1861195, "end_pos": 1853048, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010039392.1", "url": "https://www.ensembl.org/id/ENSGALT00010039392.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010022721.1", "url": "https://www.ensembl.org/id/ENSGALP00010022721.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 50, "start_aa": "Thr", "end_pos": 50, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr50", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:422183", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422183", "resource": "KEGG Pathway" }, { "id": "R-GGA-159227", "name": "", "url": 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"https://www.reactome.org/PathwayBrowser/#R-GGA-1855196", "resource": "Reactome", "description": "IP3 and IP4 transport between cytosol and nucleus" }, { "id": "R-GGA-1855229", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1855229", "resource": "Reactome", "description": "IP6 and IP7 transport between cytosol and nucleus" }, { "id": "R-GGA-191859", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-191859", "resource": "Reactome", "description": "snRNP Assembly" }, { "id": "R-GGA-3108214", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3108214", "resource": "Reactome", "description": "SUMOylation of DNA damage response and repair proteins" }, { "id": "R-GGA-3232142", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3232142", "resource": "Reactome", "description": "SUMOylation of ubiquitinylation proteins" }, { "id": "R-GGA-3301854", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3301854", "resource": "Reactome", "description": "Nuclear Pore Complex (NPC) Disassembly" }, { "id": "R-GGA-4085377", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-4085377", "resource": "Reactome", "description": "SUMOylation of SUMOylation proteins" }, { "id": "R-GGA-4551638", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-4551638", "resource": "Reactome", "description": "SUMOylation of chromatin organization proteins" }, { "id": "R-GGA-4615885", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-4615885", "resource": "Reactome", "description": "SUMOylation of DNA replication proteins" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3Q1M9H9-1", "protein_name": "Nuclear pore glycoprotein p62", "gene_name": "NUP62", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": 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"MSGFNFGGTGAPAGGFTFGTAKTATTTPATGFSFSTSGTGGFNFGTPSQPATTTPSTGLFSLTTQAPTTQTPGFNFGTTPASGGTGFSLGISTPKLNLSNTAATPATANTGSFGLGSSTLTNAVSSAGTSSQGTAPTGFVFGSSTTSAPSTGSTGFSFTSGNTSQPGASGFNIGSVGSSAQPTALSGSPFTPATMVTTTAGAAQPAAAAAAAAPTAATTSTGSTLFASIAPAPASSSATVLSLSAPVTTAATPSAGTLGFSLKAPGAAPGTSTTSTTSTTSTASTTTTGFALSLKPLVPTGSSSVAATGTPLPGSSTAAGTSTGPAMTYAQLESLINKWSLELEDQERHFLQQATQVNAWDRTLIENGEKITSLHREVEKVKLDQKRLDQELDFILSQQKELEDLLSPLEESVKEQSGTIYLQHADEEREKTFKLAENIDAQLKRMAQDLKDIIEHLNMAGGPADTSDPLQQICKILNAHMDSLQWVDQSSALLQRRVEEASRVCEGRRKEQERSLRIAFD", "length": 521 }, "evidence": [ { "id": "A0A8V0YP00", "url": "https://omabrowser.org/oma/group/A0A8V0YP00/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P17955-1", "protein_name": "Nuclear pore glycoprotein p62", "gene_name": "Nup62", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSGFNFGGTGAPAGGFTFGTAKTATTTPATGFSFSASGTGTGGFNFGTPSQPAATTPSTSLFSLATQTSTTQTPGFNFGTTPASGGTGFSLGISTPKLSLSSTAATPATANTGSFGLGSSTLTNAISGASTSSQGTAPTGFVFGSSTTSAPSTGTTGFSFTSGSASQPGASGFNIGSVGSLAQPTALSGSPFTPATLATTTAGATQPAAATPTAATTSAGSTLFASIAAAPASSSTTVLSLSAPATTAATPTAGTLGFSLKAPGAAPGASTTSTTTTTTTTTTTASTSSSTTTTGFALSLKPLVPAGPSSVAATALPASSTAVGTTTGPAMTYAQLESLINKWSLELEDQERHFLQQATQVNAWDRTLIENGEKITSLHREVEKVKLDQKRLDQELDFILSQQKELEDLLSPLEESVKEQSGTIYLQHADEEREKTYKLAENIDAQLKRMAQDLKDIIEHLNMAGGPADTSDPLQQICKILNAHMDSLQWVDQSSALLQRRVEEASRVCESRRKEQERSLRIAFD", "length": 525 }, "evidence": [ { "id": "A0A8V0YP00", "url": "https://omabrowser.org/oma/group/A0A8V0YP00/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P37198-1", "protein_name": "Nuclear pore glycoprotein p62", "gene_name": "NUP62", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSGFNFGGTGAPTGGFTFGTAKTATTTPATGFSFSTSGTGGFNFGAPFQPATSTPSTGLFSLATQTPATQTTGFTFGTATLASGGTGFSLGIGASKLNLSNTAATPAMANPSGFGLGSSNLTNAISSTVTSSQGTAPTGFVFGPSTTSVAPATTSGGFSFTGGSTAQPSGFNIGSAGNSAQPTAPATLPFTPATPAATTAGATQPAAPTPTATITSTGPSLFASIATAPTSSATTGLSLCTPVTTAGAPTAGTQGFSLKAPGAASGTSTTTSTAATATATTTSSSSTTGFALNLKPLAPAGIPSNTAAAVTAPPGPGAAAGAAASSAMTYAQLESLINKWSLELEDQERHFLQQATQVNAWDRTLIENGEKITSLHREVEKVKLDQKRLDQELDFILSQQKELEDLLSPLEELVKEQSGTIYLQHADEEREKTYKLAENIDAQLKRMAQDLKDIIEHLNTSGAPADTSDPLQQICKILNAHMDSLQWIDQNSALLQRKVEEVTKVCEGRRKEQERSFRITFD", "length": 522 }, "evidence": [ { "id": "A0A8V0YP00", "url": "https://omabrowser.org/oma/group/A0A8V0YP00/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q63850-1", "protein_name": "Nuclear pore glycoprotein p62", "gene_name": "Nup62", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSGFNFGGTGAPAGGFTFGTAKTATTTPATGFSFSASGTGTGGFNFGTPSQPAATTPSTSLFSLTTQTPTTQTPGFNFGTTPASGGTGFSLGISTPKLSLSNAAATPATANTGSFGLGSSTLTNAISSGSTSNQGTAPTGFVFGSSTTSAPSTGSTGFSFTSGSASQPGASGFSLGSVGSSAQPTALSGSPFTPATLVTTTAGATQPAAAAPTAATTSAGSTLFASIAAAPASSSATGLSLPAPVTTAATPSAGTLGFSLKAPGAAPGASTTSTTTTTTTTTTTAAAAAASTTTTGFALSLKPLVSAGPSSVAATALPASSTAAGTATGPAMTYAQLESLINKWSLELEDQERHFLQQATQVNAWDRTLIENGEKITSLHREVEKVKLDQKRLDQELDFILSQQKELEDLLSPLEESVKEQSGTIYLQHADEEREKTYKLAENIDAQLKRMAQDLKDIIEHLNMAGGPADTSDPLQQICKILNAHMDSLQWVDQSSALLQRRVEEASRVCEGRRKEQERSLRIAFD", "length": 526 }, "evidence": [ { "id": "A0A8V0YP00", "url": "https://omabrowser.org/oma/group/A0A8V0YP00/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q86IX4-1", "protein_name": "Nuclear pore protein", "gene_name": "nup62", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSNNLFGTGSSTSSSLFGSTPSAGGLFGGGSSTTPATGGGGLFGGASTTPATGGGLFGGASTTPATGGGLFGGASTTPATGGGGLFGGSSTTAPATGGGGLFGGSTTTAPATTGGLFGGSSTTAPSTTTGGLFGGSSTTTPSITTTGGLFGGASTTAPSTTTGGLFGATTPATTATTTTGGLFGGSTTTPSLTSGGGLFGATTPAATTTTTSSAIPSLTSGGGLFGGSTTTPSLTSGGLFGATTPAATTTTSTTTPSLTSGGLFGATTPSTTGGLFGASTTTTTTPSTTSTTTPSTTTGGLFGATTPATTTTSGGLFGASTTTPSTTGGLFGVSTTTPSTTSATTPTTTTTGGLFGAATTSATTPSTTTTTTTTTPTTGLFGSSTTPSTTTSGGLFGSSTTPSTTTTTTTATTPTTGGLFGSSTTPSTTTTSGGLFGSSATPSTTSSGGLFGATTTSATTTTTTPTTTSGGLFGTSSTTTTTTTPAAVAATSSNPLTTSMLGGSSTTPNPVSASLNNSDPIGINESKLLEQLLNEWVSEIENQTKNFYDQAKTIFVWDQRIMDNSQKLGKLMDVVVKLNSQQNALNQCIDVVRDQQALLERSLNALDSKIKSSPKDNETTADLERERIYSLATKIDDDIIKVENKLLGVVNKINQNQVKDDNPKDLNQKVSKILNDHLNTLQWIDKSTNILQESLKVIESTSLPETSRR", "length": 709 }, "evidence": [ { "id": "A0A8V0YP00", "url": "https://omabrowser.org/oma/group/A0A8V0YP00/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q8L7F7-1", "protein_name": "Nuclear pore complex protein NUP62", "gene_name": "NUP62", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSGFPFGQSNSVGGFSFGSSSATNSSSASSTTSPLSFSFNQSSNPSSTGFGFGSSVSSTPASSTTPSFGFGASSTPSFGFGSSASSSTPSFGFGSSASVTPASTTPSFGFGTAASSSAPAPSLFGSSTTNASSAAPGSSPFGFVTSSASSTATPSSSLFGAPASSAATPSSSPFGAAPASGSTPLFGSSPSLFSAPSSASASNSSLFGASSSAATSTSPLFGAPSSATGATPSFSVASSAPGSSSSIFGATGSSPSFSVASSASGSSPSIFGATGSSPFFGSSSSAGSTPSLFASSSSGATTSSPSPFGVSTFNSSSTSNTSNASASPFSASTGFSFLKSTASSTTSSTTPSAPPQTASSSSSFSFGTSANSGFNLSTGSSAAPASSTSGAVFSIATTTTTSSSTPAATSAPASSAPASTMAFPSFGVTSSATNTTPASSAATFSTTGFGLASSTPATGSTNSFTGFAVPKTSTPASSSQPQTTSPAFSFSLPSSTSTTAPATSSATTTQTTLVVPSSSGTSTAVAPVAGSPKLPSEITGKTVEEIIKEWNTELQERTGRFRKQANAIAEWDKRILQNRDVLLRLEIEVAKVVETQSSLERQLELIETHQQEVDKALQSMEEEAERIYNDERKSLLDDEAASTRDAMYEQSELVERELEHMTEQIRSIIQSVNANQGGELEAIDGMSPLDVVVRILNNQLSSLMWIDEKAEEFSSRIQKIALQGSGGDRELMAPKHWMS", "length": 739 }, "evidence": [ { "id": "A0A8V0YP00", "url": "https://omabrowser.org/oma/group/A0A8V0YP00/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 17, "go_terms": [ { "name": "positive regulation of centriole replication", "id": "GO:0046601", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046601", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YP00", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP00" } ], "pmid": "" }, { "name": "positive regulation of mitotic cytokinetic process", "id": "GO:1903438", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903438", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YP00", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP00" } ], "pmid": "" }, { "name": "cell surface receptor signaling pathway", "id": "GO:0007166", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007166", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YP00", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP00" } ], "pmid": "" }, { "name": "negative regulation of cell population proliferation", "id": "GO:0008285", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008285", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YP00", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP00" } ], "pmid": "" }, { "name": "negative regulation of apoptotic process", "id": "GO:0043066", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043066", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YP00", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP00" } ], "pmid": "" }, { "name": "positive regulation of canonical NF-kappaB signal transduction", "id": "GO:0043123", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043123", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YP00", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP00" } ], "pmid": "" }, { "name": "positive regulation of DNA-templated transcription", "id": "GO:0045893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045893", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YP00", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP00" } ], "pmid": "" }, { "name": "positive regulation of protein localization to centrosome", "id": "GO:1904781", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904781", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YP00", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP00" } ], "pmid": "" }, { "name": "mitotic metaphase chromosome alignment", "id": "GO:0007080", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007080", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YP00", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP00" } ], "pmid": "" }, { "name": "regulation of mitotic spindle organization", "id": "GO:0060236", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060236", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YP00", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP00" } ], "pmid": "" }, { "name": "mitotic centrosome separation", "id": "GO:0007100", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007100", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YP00", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP00" } ], "pmid": "" }, { "name": "positive regulation of mitotic nuclear division", "id": "GO:0045840", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045840", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YP00", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP00" } ], "pmid": "" }, { "name": "mRNA transport", "id": "GO:0051028", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051028", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YP00", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP00" } ], "pmid": "" }, { "name": "centriole assembly", "id": "GO:0098534", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098534", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YP00", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP00" } ], "pmid": "" }, { "name": "RNA export from nucleus", "id": "GO:0006405", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006405", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YP00", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP00" } ], "pmid": "" }, { "name": "protein import into nucleus", "id": "GO:0006606", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006606", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YP00", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP00" } ], "pmid": "" }, { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YP00", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP00" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 10, "go_terms": [ { "name": "spindle pole", "id": "GO:0000922", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000922", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YP00", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP00" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YP00", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP00" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YP00", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP00" } ], "pmid": "" }, { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YP00", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP00" } ], "pmid": "" }, { "name": "nuclear membrane", "id": "GO:0031965", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031965", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YP00", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP00" } ], "pmid": "" }, { "name": "Flemming body", "id": "GO:0090543", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090543", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YP00", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP00" } ], "pmid": "" }, { "name": "ribonucleoprotein complex", "id": "GO:1990904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990904", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YP00", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP00" } ], "pmid": "" }, { "name": "nuclear pore central transport channel", "id": "GO:0044613", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044613", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YP00", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP00" } ], "pmid": "" }, { "name": "mitotic spindle", "id": "GO:0072686", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072686", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YP00", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP00" } ], "pmid": "" }, { "name": "nuclear pore", "id": "GO:0005643", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005643", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YP00", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP00" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "phospholipid binding", "id": "GO:0005543", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005543", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YP00", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP00" } ], "pmid": "" }, { "name": "SH2 domain binding", "id": "GO:0042169", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042169", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YP00", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP00" } ], "pmid": "" }, { "name": "ubiquitin binding", "id": "GO:0043130", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043130", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YP00", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP00" } ], "pmid": "" }, { "name": "signaling receptor complex adaptor activity", "id": "GO:0030159", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030159", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YP00", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP00" } ], "pmid": "" }, { "name": "structural constituent of nuclear pore", "id": "GO:0017056", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017056", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YP00", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP00" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 511, "end_pos": 513, "annotation": "n_glycosylation_sequon" }, { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YP00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP00" }, { "id": "PF05064", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05064" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Nucleoporin NSP1-like C-terminal", "eco_id": "ECO_0000259", "start_pos": 371, "end_pos": 481, "start_aa": "Thr", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 50 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 511, "end_pos": 513 }, { "start_pos": 5, "end_pos": 7 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": 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"sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YP09-1", "uniprot_ac": "A0A8V0YP09", "uniprot_id": "A0A8V0YP09_CHICK", "mass": { "chemical_mass": 41370.0, "monoisotopic_mass": 41370.0 }, "refseq": { "ac": "XP_015141341", "name": "myb/SANT-like DNA-binding domain-containing protein 1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015141341" }, "gene_names": [ { "name": "MSANTD1", "type": "recommended", "evidence": [ { "id": "A0A8V0YP09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP09" } ] }, { "name": "MSANTD1", "type": "synonym", "evidence": [ { "id": "XP_015141341", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015141341" } ] } ], "protein_names": [ { "name": "Myb/SANT-like DNA-binding domain-containing protein 1", "type": "recommended", "evidence": [ { "id": "A0A8V0YP09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP09/entry#names_and_taxonomy" } ] }, { "name": "myb/SANT-like DNA-binding domain-containing protein 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015141341", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015141341" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052535.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015141341", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015141341" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YP09", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP09" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MSANTD1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP09", "locus": { "chromosome": "4", "start_pos": 81585156, "end_pos": 81638228, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010016369", "url": "https://www.ensembl.org/id/ENSGALG00010016369" } ] } } ], "crossref": [ { "id": "A0A8V0YP09", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YP09", "database": "AlphaFoldDB", "categories": [] }, { "id": "422877", "url": "https://www.ncbi.nlm.nih.gov/gene/422877", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR026095", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026095", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044822", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044822", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:422877", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422877", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YP09", "url": "https://www.orthodb.org/?gene=A0A8V0YP09", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YVF6", "url": "https://www.orthodb.org/?gene=A0A8V0YVF6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YVS7", "url": "https://www.orthodb.org/?gene=A0A8V0YVS7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YXF4", "url": "https://www.orthodb.org/?gene=A0A8V0YXF4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z280", "url": "https://www.orthodb.org/?gene=A0A8V0Z280", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22666", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22666", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22666:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22666:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13837", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13837", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015141341", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015141341", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YP09", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP09", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YP09-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP09-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YVF6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YVF6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YVF6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YVF6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YVS7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YVS7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YVS7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YVS7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YXF4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXF4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YXF4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXF4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z280", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z280", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z280-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z280-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEDLLFPGQQVPKIFFHNVKNPRAINVQVCALLFPKPVLPYCSTSENQGKGTQKSVLGQQFLSVEKLLCCLLFSWRRSRPSLLQTLARICFTGQSAMAAAEIPSYIVSSQTEKHRRARNWTDAEMRGLMLVWEEFFDELKQTKRNAKVYEKMANKLFEMTGEIRHGEEIKIKITNMTFQYRKLKCMTDSETVAPDWPYYKTIDRILSKVTDHSDVKMHENQQPGPSTSQTEASQSPSAKSTPLYLPYNQFTYEGREECFEDEHSESSSSLLSYKLRTEERPVKKRKMQSCSFQKKKLKLMEAMLEEQKKLSRAMEETCREVRRILDQQNIIQVQSLQLQERMMNLLEKMISKSNV", "length": 355, "header": "tr|A0A8V0YP09-1|A0A8V0YP09_CHICK Isoform 1 of Myb/SANT-like DNA-binding domain-containing protein 1 OS=Gallus gallus OX=9031 GN=MSANTD1 PE=4 SV=1 CANONICAL=A0A8V0YP09-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YP09-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP09/entry#A0A8V0YP09-1", "sequence": { "sequence": "MEDLLFPGQQVPKIFFHNVKNPRAINVQVCALLFPKPVLPYCSTSENQGKGTQKSVLGQQFLSVEKLLCCLLFSWRRSRPSLLQTLARICFTGQSAMAAAEIPSYIVSSQTEKHRRARNWTDAEMRGLMLVWEEFFDELKQTKRNAKVYEKMANKLFEMTGEIRHGEEIKIKITNMTFQYRKLKCMTDSETVAPDWPYYKTIDRILSKVTDHSDVKMHENQQPGPSTSQTEASQSPSAKSTPLYLPYNQFTYEGREECFEDEHSESSSSLLSYKLRTEERPVKKRKMQSCSFQKKKLKLMEAMLEEQKKLSRAMEETCREVRRILDQQNIIQVQSLQLQERMMNLLEKMISKSNV", "length": 355, "header": "tr|A0A8V0YP09-1|A0A8V0YP09_CHICK Isoform 1 of Myb/SANT-like DNA-binding domain-containing protein 1 OS=Gallus gallus OX=9031 GN=MSANTD1 PE=4 SV=1 CANONICAL=A0A8V0YP09-1" }, "locus": { "chromosome": "4", "start_pos": 81614814, "end_pos": 81586464, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010039412.1", "url": "https://www.ensembl.org/id/ENSGALT00010039412.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010022735.1", "url": "https://www.ensembl.org/id/ENSGALP00010022735.1" } ] } }, { "isoform_ac": "A0A8V0YVF6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP09/entry#A0A8V0YVF6-1", "sequence": { "sequence": "MTPRQQIVCLKGQSAMAAAEIPSYIVSSQTEKHRRARNWTDAEMRGLMLVWEEFFDELKQTKRNAKVYEKMANKLFEMTGEIRHGEEIKIKITNMTFQYRKLKCMTDSETVAPDWPYYKTIDRILSKVTDHSDVKMHENQQPGPSTSQTEASQSPSAKSTPLYLPYNQFTYEGREECFEDEHSESSSSLLSYKLRTEERPVKKRKMQSCSFQKKKLKLMEAMLEEQKKLSRAMEETCREVRRILDQQNIIQVQSLQLQERMMNLLEKMISKSNV", "length": 274, "header": "tr|A0A8V0YVF6-1|A0A8V0YVF6_CHICK Computationally mapped isoform of Myb/SANT-like DNA-binding domain-containing protein 1 OS=Gallus gallus OX=9031 GN=MSANTD1 PE=4 SV=1 CANONICAL=A0A8V0YP09-1" }, "locus": { "chromosome": "4", "start_pos": 81602104, "end_pos": 81586464, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010039409.1", "url": "https://www.ensembl.org/id/ENSGALT00010039409.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010022732.1", "url": "https://www.ensembl.org/id/ENSGALP00010022732.1" } ] } }, { "isoform_ac": "A0A8V0YVS7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP09/entry#A0A8V0YVS7-1", "sequence": { "sequence": "MEDLLFPGQQVCALLFPKPVLPYCSTSENQGKGTQKSVLGQQFLSVEKLLCCLLFSWRRSRPSLLQTLARICFTGQSAMAAAEIPSYIVSSQTEKHRRARNWTDAEMRGLMLVWEEFFDELKQTKRNAKVYEKMANKLFEMTGEIRHGEEIKIKITNMTFQYRKLKCMTDSETVAPDWPYYKTIDRILSKVTDHSDVKMHENQQPGPSTSQTEASQSPSAKSTPLYLPYNQFTYEGREECFEDEHSESSSSLLSYKLRTEERPVKKRKMQSCSFQKKKLKLMEAMLEEQKKLSRAMEETCREVRRILDQQNIIQVQSLQLQERMMNLLEKMISKSNV", "length": 337, "header": "tr|A0A8V0YVS7-1|A0A8V0YVS7_CHICK Computationally mapped isoform of Myb/SANT-like DNA-binding domain-containing protein 1 OS=Gallus gallus OX=9031 GN=MSANTD1 PE=4 SV=1 CANONICAL=A0A8V0YP09-1" }, "locus": { "chromosome": "4", "start_pos": 81614814, "end_pos": 81586464, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010039404.1", "url": "https://www.ensembl.org/id/ENSGALT00010039404.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010022729.1", "url": "https://www.ensembl.org/id/ENSGALP00010022729.1" } ] } }, { "isoform_ac": "A0A8V0YXF4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP09/entry#A0A8V0YXF4-1", "sequence": { "sequence": "MKHCTSKSRILQFSPTTFCTASPVPCQSAMAAAEIPSYIVSSQTEKHRRARNWTDAEMRGLMLVWEEFFDELKQTKRNAKVYEKMANKLFEMTGEIRHGEEIKIKITNMTFQYRKLKCMTDSETVAPDWPYYKTIDRILSKVTDHSDVKMHENQQPGPSTSQTEASQSPSAKSTPLYLPYNQFTYEGREECFEDEHSESSSSLLSYKLRTEERPVKKRKMQSCSFQKKKLKLMEAMLEEQKKLSRAMEETCREVRRILDQQNIIQVQSLQLQERMMNLLEKMISKSNV", "length": 288, "header": "tr|A0A8V0YXF4-1|A0A8V0YXF4_CHICK Computationally mapped isoform of Myb/SANT-like DNA-binding domain-containing protein 1 OS=Gallus gallus OX=9031 GN=MSANTD1 PE=4 SV=1 CANONICAL=A0A8V0YP09-1" }, "locus": { "chromosome": "4", "start_pos": 81638029, "end_pos": 81586464, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010039415.1", "url": "https://www.ensembl.org/id/ENSGALT00010039415.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010022738.1", 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"MAENFDRAPGAGRGRGRGGSVLSGASESGGGACPGGGGSHGSGAVEQQQNKTSGLLPQQEPLRPPRTAPLGTGSSEHLQQTRIPSGSRVSIPSSGPEMSKPQVAVTPVAMSKLSVKAPEFYPSGYNPNFNQNLADSSFEDGYGGYLTLAEYVQGFLNHLTEQPGCFETEIEQFAETLNGWVITDEALQELVDLIYQQATSVPNFSYMGARLCNYLSHNLTISPQSGNFRQLLLKRCRAEFENRDEAAKGDEVTRKQFHAFVLFLGELYLNLEIKGTKGQVTRAEILQEGLRELLNALFSNPVDSNLICAVKLLKLTGSVLEDAWKEKGKDDMTEVIQRIENVVLDANCSRDVKHMLLKLVELRSSNWGRVLGTSSHTEATPENDPNYFMNEPTFYTSDGIPFTAADPDYQEEYQELLEREDWFPDYEENGTDLSGAGDLCFDDIDDEMDPEIEEAYEKFCLESEHGRKQENNES", "length": 474, "header": "tr|A0A8V0YQX8-1|A0A8V0YQX8_CHICK Isoform 1 of Polyadenylate-binding protein-interacting protein 1 OS=Gallus gallus OX=9031 GN=PAIP1 PE=1 SV=1 CANONICAL=A0A8V0YQX8-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YP30-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQX8/entry#A0A8V0YP30-1", "sequence": { "sequence": "MSKPQVAVTPVAMSKLSVKAPEFYPSGYNPNFNQNLADSSFEDGYGGYLTLAEYVQGFLNHLTEQPGCFETEIEQFAETLNGWVITDEALQELVDLIYQQVVCPNFSYMGARLCNYLSHNLTISPQSGNFRQLLLKRCRAEFENRDEAAKGDEVTRKQFHAFVLFLGELYLNLEIKGTKGQVTRAEILQEGLRELLNALFSNPVDSNLICAVKLLKLTGSVLEDAWKEKGKDDMTEVIQRIENVVLDANCSRDVKHMLLKLVELRSSNWGRVLGTSSHTEATPENDPNYFMNEPTFYTSDGIPFTAADPDYQEEYQELLEREDWFPDYEENGTDLSGAGDLCFDDIDDEMDPEIEEAYEKFCLESEHGRKQ", "length": 371, "header": "tr|A0A8V0YP30-1|A0A8V0YQX8_CHICK Computationally mapped isoform of Polyadenylate-binding protein-interacting protein 1 OS=Gallus gallus OX=9031 GN=PAIP1 PE=1 SV=1 CANONICAL=A0A8V0YQX8-1" }, "locus": { "chromosome": "Z", "start_pos": 14276633, "end_pos": 14259910, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034913.1", "url": "https://www.ensembl.org/id/ENSGALT00010034913.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020426.1", "url": "https://www.ensembl.org/id/ENSGALP00010020426.1" } ] } }, { "isoform_ac": "A0A8V0YP63-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQX8/entry#A0A8V0YP63-1", "sequence": { "sequence": "MAENFDRAPGAGRGRGRGGSVLSGASESGGGACPGGGGSHGSGAVEQQQNKTSGLLPQQEPLRPPRTAPLGTGSSEHLQQTRIPSGSRVSIPSSGPEMSKPQVAVTPVAMSKLSVKAPEFYPSGYNPNFNQNLADSSFEDGYGGYLTLAEYVQGFLNHLTEQPGCFETEIEQFAETLNGWVITDEALQELVDLIYQQATSVPNFSYMGARLCNYLSHNLTISPQSGNFRQLLLKRCRAEFENRDEAAKGDEVTRKQFHAFVLFLGELYLNLEIKGTKGQVTRAEILQEGLRELLNALFSNPVDSNLICAVKLLKLTGSVLEDAWKEKGKDDMTEVIQRIENVVLDANCSRDVKHMLLKLVELRSSNWGRVLGTSSHTEATPENDPNYFMNEPTFYTSDGIPFTAADPDYQEEYQELLEREDWFPDYEENGTDLSGAGDLCFDDIDDEMDPEIEEAYEKFCLESEHGRKQ", "length": 469, "header": "tr|A0A8V0YP63-1|A0A8V0YP63_CHICK Computationally mapped isoform of Polyadenylate-binding protein-interacting protein 1 OS=Gallus gallus OX=9031 GN=PAIP1 PE=1 SV=1 CANONICAL=A0A8V0YQX8-1" }, "locus": { "chromosome": "Z", "start_pos": 14278036, "end_pos": 14259910, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034921.1", "url": "https://www.ensembl.org/id/ENSGALT00010034921.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020429.1", "url": "https://www.ensembl.org/id/ENSGALP00010020429.1" } ] } }, { "isoform_ac": "A0A8V0YQX8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQX8/entry#A0A8V0YQX8-1", "sequence": { "sequence": "MAENFDRAPGAGRGRGRGGSVLSGASESGGGACPGGGGSHGSGAVEQQQNKTSGLLPQQEPLRPPRTAPLGTGSSEHLQQTRIPSGSRVSIPSSGPEMSKPQVAVTPVAMSKLSVKAPEFYPSGYNPNFNQNLADSSFEDGYGGYLTLAEYVQGFLNHLTEQPGCFETEIEQFAETLNGWVITDEALQELVDLIYQQATSVPNFSYMGARLCNYLSHNLTISPQSGNFRQLLLKRCRAEFENRDEAAKGDEVTRKQFHAFVLFLGELYLNLEIKGTKGQVTRAEILQEGLRELLNALFSNPVDSNLICAVKLLKLTGSVLEDAWKEKGKDDMTEVIQRIENVVLDANCSRDVKHMLLKLVELRSSNWGRVLGTSSHTEATPENDPNYFMNEPTFYTSDGIPFTAADPDYQEEYQELLEREDWFPDYEENGTDLSGAGDLCFDDIDDEMDPEIEEAYEKFCLESEHGRKQENNES", "length": 474, "header": "tr|A0A8V0YQX8-1|A0A8V0YQX8_CHICK Isoform 1 of Polyadenylate-binding protein-interacting protein 1 OS=Gallus gallus OX=9031 GN=PAIP1 PE=1 SV=1 CANONICAL=A0A8V0YQX8-1" }, "locus": { "chromosome": "Z", "start_pos": 14278036, "end_pos": 14257817, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034931.1", "url": "https://www.ensembl.org/id/ENSGALT00010034931.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020435.1", "url": "https://www.ensembl.org/id/ENSGALP00010020435.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 106, "start_aa": "Thr", "end_pos": 106, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr106", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:427195", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427195", "resource": "KEGG Pathway" }, { "id": "R-GGA-429947", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-429947", "resource": "Reactome", "description": "Deadenylation of mRNA" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQX8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQX8" } ], "pmid": "" }, { "name": "translation activator activity", "id": "GO:0008494", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008494", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQX8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQX8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQX8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQX8" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQX8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQX8" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQX8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQX8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "regulation of translation", "id": "GO:0006417", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006417", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQX8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQX8" } ], "pmid": "" }, { "name": "CRD-mediated mRNA stabilization", "id": "GO:0070934", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070934", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQX8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQX8" } ], "pmid": "" }, { "name": "positive regulation of cytoplasmic translation", "id": "GO:2000767", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000767", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQX8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQX8" } ], "pmid": "" }, { "name": "regulation of translational initiation", "id": "GO:0006446", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006446", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQX8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQX8" } ], "pmid": "" }, { "name": "host-mediated activation of viral process", "id": "GO:0044794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044794", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQX8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQX8" } ], "pmid": "" }, { "name": "negative regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay", "id": "GO:1900152", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1900152", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQX8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQX8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 203, "end_pos": 205, "annotation": "n_glycosylation_sequon" }, { "start_pos": 218, "end_pos": 220, "annotation": "n_glycosylation_sequon" }, { "start_pos": 347, "end_pos": 349, "annotation": "n_glycosylation_sequon" }, { "start_pos": 429, "end_pos": 431, "annotation": "n_glycosylation_sequon" }, { "start_pos": 472, "end_pos": 474, "annotation": "n_glycosylation_sequon" }, { "start_pos": 50, "end_pos": 52, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YQX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQX8" }, { "id": "SM00543", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00543" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "MIF4G", "eco_id": "ECO_0000259", "start_pos": 149, "end_pos": 366, "start_aa": "Ala", "end_aa": "Asn", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 106 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 203, "end_pos": 205 }, { "start_pos": 218, "end_pos": 220 }, { "start_pos": 347, "end_pos": 349 }, { "start_pos": 429, "end_pos": 431 }, { "start_pos": 472, "end_pos": 474 }, { "start_pos": 50, "end_pos": 52 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { 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"phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YP31-1", "uniprot_ac": "A0A8V0YP31", "uniprot_id": "A0A8V0YP31_CHICK", "mass": { "chemical_mass": 173798.0, "monoisotopic_mass": 173798.0 }, "refseq": { "ac": "XP_040518467", "name": "uncharacterized protein LOC121109116", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040518467" }, "gene_names": [ { "name": "LOC121109116", "type": "recommended", "evidence": [ { "id": "A0A8V0YP31", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP31" } ] }, { "name": "LOC121109116", "type": "synonym", "evidence": [ { "id": "XP_040518467", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040518467" } ] } ], "protein_names": [ { "name": "ADP-ribosylhydrolase like 1", "type": "synonym", "evidence": [ { "id": "A0A8V0YP31", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP31/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein LOC121109116", "type": "synonym", "evidence": [ { "id": "XP_040518467", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040518467" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040518467", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040518467" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YP31", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP31" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LOC121109116", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP31", "locus": {} } ], "crossref": [ { "id": "121109116", "url": "https://www.ncbi.nlm.nih.gov/gene/121109116", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "GQKCFPE", "url": "https://omabrowser.org/oma/group/GQKCFPE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YP31", "url": "https://www.orthodb.org/?gene=A0A8V0YP31", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "XP_040518467", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040518467", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YP31", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP31", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YP31-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP31-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLIDPLVLKKKLNRMVTEQGAFAVLSSLLLYVTELAACDPQLRSKRTKWEEGKENQVSCKQSSPDSNRGCYPTRFQLLRSRFLNTNREPYVKKRREVGKLVIKERLWVNRAGNKLERRGDGKAAEEGEDTAPSERVRWGSVTGKNTVKNILKKFLAAEEKEDKEKIPTWKKKGPNSSLPKIVNRSSVLSKLKEQFEQSSLCSATEVKASLLRKGEKKMKTLPSRKAIRKPEVRVLRMAALAATDINGPESQYLVCSMVPVPRLSMATEINHPWSWSKNNATMQPCDHNTGLKEKENSERKPGENKTPLRAAQDMEDKEEPVAPKEMPDAKDSTETNTDSSKQRPQFNPSLDSSFSICKNKALPDCDVLSSEHNLDCDRNKLPAGPDTSSPTRTTKAVQHVKDDSPPSNVPYSSTAEGSSEPSPQDTKTDEIPKIIMHVYSLEEADQDLTEPEKDPFFAGQKCFPEQEVLENTLPFYSPGDQALCEVEPPMQNRHLSHITQAASKRPLPVQKEAPGLRGRGSKEDKKGEKYHSEDKMYSTSSKNYSDISATKEQENKTPNCQMQNEPQTKQPQPPQMPSPQNHFSNSNAEISNTDANQTKPTLSSSDLQKQKNGVAEDHIPSDWDKKEGPLPDEFVRHKLYLVDEEFGKDQLPSANEMMSPSNNGVLDRSTFTDLETCYKPSNNFIECEETTADEVPWPDSEVWLSPSSNPVTTLMSGIVGQRIHHTLGNPPALPPTGLVTPGAGGVDDEYASRGSEKHPPPSSDESAVHENNAAVEKKTACDFNNQPLSPNHSTENEYAAAEETIPCQSLENCLSFSTKKIGKHANKTVLARNPLLPLERNQTQISDDTEKQGSDTLEENLFPSSELVSGQKKCAKGTDNVSKHEKHKPLPSDNDTKHGDDRMETEEREELDVLYKFEQEQVSTPSDLMDHDNNSSSGNNAHSPQTSQLPPSEHDTNIQGVKSSGQGLKCLAPTRDFIKRDHDLTADGNICCSNEKHQLPSSSEPTRRTNGTAGKRNLKLNFKDYSVLPRNTARHDDKTSDEENSFQDMKDSTVQHEKGFEGERNTSHDPKNQMPSSSPLVKQDKKFSPLDTRQQGASGDSVKPETKLAEKKTKHTSEKPQSPSNRVERPQERSSSAEKKQKAPEAEDVKSPETKAVTGDDEHQHRGQHQLPLSSKSAKPGKNVPGGEKQQASSEDFTMPDSNAKEKKKSLRPRKYRSVSSETAVLPQEKHSPDQKQQTPATAGFKKPETDVVKEKDEEPNSEKLPTPPSNKGVNFKEKNSLGERKQKMSAAGDAMPPKTKVAKEDDEHQHSGNQQLPPSSKPAKPGKKTPGERKHETVTEGFRKPDTNSVKDKSKDPGSGMCQSSTPDLLLKLQEENVTAKKKPSTPPSDKKIVDRTGSTEKRSGPRGVEEYQRQPSDKKGKHSIHSSGKEGSESYQTAFPSDGGESESDSVPKETNLSKTEKSSKSSPSRGASKYDDSPTESRKKQPGFKKYRALSSKGLVKDEGGTAGREAGWQAAGTASGRKAELGDCSKTAPFSKYTVESYSEGPLDSSFKPLIIRVTDTFKHHS", "length": 1570, "header": "tr|A0A8V0YP31-1|A0A8V0YP31_CHICK Isoform 1 of ADP-ribosylhydrolase like 1 OS=Gallus gallus OX=9031 GN=LOC121109116 PE=4 SV=1 CANONICAL=A0A8V0YP31-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YP31-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP31/entry#A0A8V0YP31-1", "sequence": { "sequence": "MLIDPLVLKKKLNRMVTEQGAFAVLSSLLLYVTELAACDPQLRSKRTKWEEGKENQVSCKQSSPDSNRGCYPTRFQLLRSRFLNTNREPYVKKRREVGKLVIKERLWVNRAGNKLERRGDGKAAEEGEDTAPSERVRWGSVTGKNTVKNILKKFLAAEEKEDKEKIPTWKKKGPNSSLPKIVNRSSVLSKLKEQFEQSSLCSATEVKASLLRKGEKKMKTLPSRKAIRKPEVRVLRMAALAATDINGPESQYLVCSMVPVPRLSMATEINHPWSWSKNNATMQPCDHNTGLKEKENSERKPGENKTPLRAAQDMEDKEEPVAPKEMPDAKDSTETNTDSSKQRPQFNPSLDSSFSICKNKALPDCDVLSSEHNLDCDRNKLPAGPDTSSPTRTTKAVQHVKDDSPPSNVPYSSTAEGSSEPSPQDTKTDEIPKIIMHVYSLEEADQDLTEPEKDPFFAGQKCFPEQEVLENTLPFYSPGDQALCEVEPPMQNRHLSHITQAASKRPLPVQKEAPGLRGRGSKEDKKGEKYHSEDKMYSTSSKNYSDISATKEQENKTPNCQMQNEPQTKQPQPPQMPSPQNHFSNSNAEISNTDANQTKPTLSSSDLQKQKNGVAEDHIPSDWDKKEGPLPDEFVRHKLYLVDEEFGKDQLPSANEMMSPSNNGVLDRSTFTDLETCYKPSNNFIECEETTADEVPWPDSEVWLSPSSNPVTTLMSGIVGQRIHHTLGNPPALPPTGLVTPGAGGVDDEYASRGSEKHPPPSSDESAVHENNAAVEKKTACDFNNQPLSPNHSTENEYAAAEETIPCQSLENCLSFSTKKIGKHANKTVLARNPLLPLERNQTQISDDTEKQGSDTLEENLFPSSELVSGQKKCAKGTDNVSKHEKHKPLPSDNDTKHGDDRMETEEREELDVLYKFEQEQVSTPSDLMDHDNNSSSGNNAHSPQTSQLPPSEHDTNIQGVKSSGQGLKCLAPTRDFIKRDHDLTADGNICCSNEKHQLPSSSEPTRRTNGTAGKRNLKLNFKDYSVLPRNTARHDDKTSDEENSFQDMKDSTVQHEKGFEGERNTSHDPKNQMPSSSPLVKQDKKFSPLDTRQQGASGDSVKPETKLAEKKTKHTSEKPQSPSNRVERPQERSSSAEKKQKAPEAEDVKSPETKAVTGDDEHQHRGQHQLPLSSKSAKPGKNVPGGEKQQASSEDFTMPDSNAKEKKKSLRPRKYRSVSSETAVLPQEKHSPDQKQQTPATAGFKKPETDVVKEKDEEPNSEKLPTPPSNKGVNFKEKNSLGERKQKMSAAGDAMPPKTKVAKEDDEHQHSGNQQLPPSSKPAKPGKKTPGERKHETVTEGFRKPDTNSVKDKSKDPGSGMCQSSTPDLLLKLQEENVTAKKKPSTPPSDKKIVDRTGSTEKRSGPRGVEEYQRQPSDKKGKHSIHSSGKEGSESYQTAFPSDGGESESDSVPKETNLSKTEKSSKSSPSRGASKYDDSPTESRKKQPGFKKYRALSSKGLVKDEGGTAGREAGWQAAGTASGRKAELGDCSKTAPFSKYTVESYSEGPLDSSFKPLIIRVTDTFKHHS", "length": 1570, "header": "tr|A0A8V0YP31-1|A0A8V0YP31_CHICK Isoform 1 of ADP-ribosylhydrolase like 1 OS=Gallus gallus OX=9031 GN=LOC121109116 PE=4 SV=1 CANONICAL=A0A8V0YP31-1" }, "locus": { "chromosome": "1", "start_pos": 137454630, "end_pos": 137449921, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034812.1", "url": "https://www.ensembl.org/id/ENSGALT00010034812.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020398.1", "url": "https://www.ensembl.org/id/ENSGALP00010020398.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 1010, "end_pos": 1012, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1065, "end_pos": 1067, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1378, "end_pos": 1380, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1458, "end_pos": 1460, "annotation": "n_glycosylation_sequon" }, { "start_pos": 175, "end_pos": 177, "annotation": "n_glycosylation_sequon" }, { "start_pos": 183, "end_pos": 185, "annotation": "n_glycosylation_sequon" }, { "start_pos": 279, "end_pos": 281, "annotation": "n_glycosylation_sequon" }, { "start_pos": 304, "end_pos": 306, "annotation": "n_glycosylation_sequon" }, { "start_pos": 543, "end_pos": 545, "annotation": "n_glycosylation_sequon" }, { "start_pos": 555, "end_pos": 557, "annotation": "n_glycosylation_sequon" }, { "start_pos": 596, "end_pos": 598, "annotation": "n_glycosylation_sequon" }, { "start_pos": 791, "end_pos": 793, "annotation": "n_glycosylation_sequon" }, { "start_pos": 826, "end_pos": 828, "annotation": "n_glycosylation_sequon" }, { "start_pos": 841, "end_pos": 843, "annotation": "n_glycosylation_sequon" }, { "start_pos": 880, "end_pos": 882, "annotation": "n_glycosylation_sequon" }, { "start_pos": 894, "end_pos": 896, "annotation": "n_glycosylation_sequon" }, { "start_pos": 933, "end_pos": 935, "annotation": "n_glycosylation_sequon" }, { "start_pos": 934, "end_pos": 936, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1010, "end_pos": 1012 }, { "start_pos": 1065, "end_pos": 1067 }, { "start_pos": 1378, "end_pos": 1380 }, { "start_pos": 1458, "end_pos": 1460 }, { "start_pos": 175, "end_pos": 177 }, { "start_pos": 183, "end_pos": 185 }, { "start_pos": 279, "end_pos": 281 }, { "start_pos": 304, "end_pos": 306 }, { "start_pos": 543, "end_pos": 545 }, { "start_pos": 555, "end_pos": 557 }, { "start_pos": 596, "end_pos": 598 }, { "start_pos": 791, "end_pos": 793 }, { "start_pos": 826, "end_pos": 828 }, { "start_pos": 841, "end_pos": 843 }, { "start_pos": 880, "end_pos": 882 }, { "start_pos": 894, "end_pos": 896 }, { "start_pos": 933, "end_pos": 935 }, { "start_pos": 934, "end_pos": 936 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", 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0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YP44-1", "uniprot_ac": "A0A8V0YP44", "uniprot_id": "A0A8V0YP44_CHICK", "mass": { "chemical_mass": 86955.0, "monoisotopic_mass": 86955.0 }, "refseq": {}, "gene_names": [ { "name": "SEC63", "type": "recommended", "evidence": [ { "id": "A0A8V0YP44", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP44" } ] } ], "protein_names": [ { "name": "Translocation protein SEC63 homolog", "type": "recommended", "evidence": [ { "id": "A0A8V0YP44", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP44/entry#names_and_taxonomy" } ] }, { "name": "DnaJ homolog subfamily C member 23", "type": "synonym", "evidence": [ { "id": "A0A8V0YP44", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP44/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Mediates cotranslational and post-translational transport of certain precursor polypeptides across endoplasmic reticulum (ER). Proposed to play an auxiliary role in recognition of precursors with short and apolar signal peptides. May cooperate with SEC62 and HSPA5/BiP to facilitate targeting of small presecretory proteins into the SEC61 channel-forming translocon complex, triggering channel opening for polypeptide translocation to the ER lumen. Required for efficient PKD1/Polycystin-1 biogenesis and trafficking to the plasma membrane of the primary cilia.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YP44", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP44#function" }, { "database": "UniProtKB", "id": "ARBA00059604", "url": "https://www.uniprot.org/uniprotkb/ARBA00059604#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YP44", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP44" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SEC63", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP44", "locus": { "chromosome": "3", "start_pos": 67315245, "end_pos": 67259744, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010014504", "url": "https://www.ensembl.org/id/ENSGALG00010014504" } ] } } ], "crossref": [ { "id": "A0A8V0YP44", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YP44", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd06257", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06257", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001623", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001623", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014756", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014756", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035892", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035892", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036869", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036869", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YP44", "url": "https://www.orthodb.org/?gene=A0A8V0YP44", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24075", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24075", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24075:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24075:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00226", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00226", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02889", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02889", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YP44", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP44", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YP44-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP44-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAGQQFQYDDSGNTFFYFLTSFVGLIVIPATYYLWPRDQHAEQIRLKNIRNVYGRCLWYRLRLLKPQQNIIPTVKKIILLAGWALFLFLAYKVSKTDREYQEYNPYEVLHLDPGASISEIKKQYRALSLKYHPDKGGDEVMFMRIAKAYAALTDEESRKNWEEFGNPDGPQATSFGIALPAWIVDQKNSILVLLVYGLAFMVILPVVVGSWWYRSIRYSGDQILIRTTQIYTYFVYKTRNMDMKRLIMVLAGASEFDPQYNKDATSRPADNVQIPQLIREIGGINLKKNEPPLTCPYSLKARVLLLTHLARMKVPDTLEEDQQFILKKSPALLQEMINVICQLIIMARSREEREFRAPSLGSLENCMKLSQMTVQGLQQFKSPLLQLPHIEEDNLRRVSNHKKYKIKSIQDLVSLKGSDRRNLLHFLEDKKYDEVMAVLGSFPYVTMDIKPQDSNNITVGSLVTVLVTLTRQTMAEVFEKEQSICSAEEQPAEDGQGDSNKVKSKGWQQKNKGTKKASKSKKKKPLKKKPVPPSLQPPKQQKQKQANGEVVVKEEEEEISDKGSESEEEETNRDSQSEKDDGSDRESDREQDEKQNKDDEAEWQELQQSIQRKERALLETKSKITHPVYSLFFPEEKQEWWWLYIADRKEQMLICMPYHVCTLKDKEEVELKFPAPGKPGNYQYTVYLRSDSYMGLDQIKPLKLEVHEAKPVPENHPQWDTAIEGDEDQEDSEGFEDSFEEEEEEEEDDD", "length": 750, "header": "tr|A0A8V0YP44-1|A0A8V0YP44_CHICK Isoform 1 of Translocation protein SEC63 homolog OS=Gallus gallus OX=9031 GN=SEC63 PE=1 SV=1 CANONICAL=A0A8V0YP44-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YP44-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP44/entry#A0A8V0YP44-1", "sequence": { "sequence": "MAGQQFQYDDSGNTFFYFLTSFVGLIVIPATYYLWPRDQHAEQIRLKNIRNVYGRCLWYRLRLLKPQQNIIPTVKKIILLAGWALFLFLAYKVSKTDREYQEYNPYEVLHLDPGASISEIKKQYRALSLKYHPDKGGDEVMFMRIAKAYAALTDEESRKNWEEFGNPDGPQATSFGIALPAWIVDQKNSILVLLVYGLAFMVILPVVVGSWWYRSIRYSGDQILIRTTQIYTYFVYKTRNMDMKRLIMVLAGASEFDPQYNKDATSRPADNVQIPQLIREIGGINLKKNEPPLTCPYSLKARVLLLTHLARMKVPDTLEEDQQFILKKSPALLQEMINVICQLIIMARSREEREFRAPSLGSLENCMKLSQMTVQGLQQFKSPLLQLPHIEEDNLRRVSNHKKYKIKSIQDLVSLKGSDRRNLLHFLEDKKYDEVMAVLGSFPYVTMDIKPQDSNNITVGSLVTVLVTLTRQTMAEVFEKEQSICSAEEQPAEDGQGDSNKVKSKGWQQKNKGTKKASKSKKKKPLKKKPVPPSLQPPKQQKQKQANGEVVVKEEEEEISDKGSESEEEETNRDSQSEKDDGSDRESDREQDEKQNKDDEAEWQELQQSIQRKERALLETKSKITHPVYSLFFPEEKQEWWWLYIADRKEQMLICMPYHVCTLKDKEEVELKFPAPGKPGNYQYTVYLRSDSYMGLDQIKPLKLEVHEAKPVPENHPQWDTAIEGDEDQEDSEGFEDSFEEEEEEEEDDD", "length": 750, "header": "tr|A0A8V0YP44-1|A0A8V0YP44_CHICK Isoform 1 of Translocation protein SEC63 homolog OS=Gallus gallus OX=9031 GN=SEC63 PE=1 SV=1 CANONICAL=A0A8V0YP44-1" }, "locus": { "chromosome": "3", "start_pos": 67313929, "end_pos": 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"MSQPTAFLPHPSQQLGAPNCFCMGTEAMLEKGSSDLSEAEEAEIETIRQHREELLEDIKKLKEEIAQVFAEIEGFQNAEERQEADQNPGERSSKLSQRDKLLSVGRKKFNMDPEKGIQYLIEQQLLSSDLQEIAKFLHKGEGLNKTAIGDYLGGRDSKNIQILQAFVACHQFANLNLVQALRQFLWSFRLPGEAQKIDRMMEAFANWYCKCNPGVFQSTDTCYILSFSIIMLNTSLHNPNVKDKPPFERFVSINRGINDGADLPEELLKNLFDSIKNEPFSIPEDDGNDLTHTFFNPNREGWLLKLGGRVKTWKRRWFILTDNCLYYFEYTTDKEPLGIIPLENLSVRKVDDPKKPNCFELFNPNCKGQKIKACKTDGDGKVVEGKHQSYKISAATPAERDEWIEAIRTSITQNPFYDLVSARKKKIANKN", "length": 431, "header": "tr|A0A8V0YP53-1|A0A8V0YP53_CHICK Isoform 1 of Cytohesin 4 OS=Gallus gallus OX=9031 GN=CYTH4 PE=4 SV=1 CANONICAL=A0A8V0YP53-1" }, "locus": { "chromosome": "1", "start_pos": 51454061, "end_pos": 51426896, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034873.1", "url": "https://www.ensembl.org/id/ENSGALT00010034873.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020419.1", "url": "https://www.ensembl.org/id/ENSGALP00010020419.1" } ] } }, { "isoform_ac": "A0A8V0YQV9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP53/entry#A0A8V0YQV9-1", "sequence": { "sequence": "NSFCPPLFFLHLKTGIYSLKLKEEIAQVFAEIEGFQNAEERQEADQNPGERSSKLSQRDKLLSVGRKKFNMDPEKGIQYLIEQQLLSSDLQEIAKFLHKGEGLNKTAIGDYLGGRDSKNIQILQAFVACHQFANLNLVQALRQFLWSFRLPGEAQKIDRMMEAFANWYCKCNPGVFQSTDTCYILSFSIIMLNTSLHNPNVKDKPPFERFVSINRGINDGADLPEELLKNLFDSIKNEPFSIPEDDGNDLTHTFFNPNREGWLLKLGGRVKTWKRRWFILTDNCLYYFEYTTDKEPLGIIPLENLSVRKVDDPKKPNCFELFNPNCKGQKIKACKTDGDGKVVEGKHQSYKISAATPAERDEWIEAIRTSITQNPFYDLVSARKKKIANKN", "length": 391, "header": "tr|A0A8V0YQV9-1|A0A8V0YQV9_CHICK Computationally mapped isoform of Cytohesin 4 OS=Gallus gallus OX=9031 GN=CYTH4 PE=4 SV=1 CANONICAL=A0A8V0YP53-1" }, "locus": { "chromosome": "1", "start_pos": 51438004, "end_pos": 51426896, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034860.1", "url": "https://www.ensembl.org/id/ENSGALT00010034860.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020415.1", "url": "https://www.ensembl.org/id/ENSGALP00010020415.1" } ] } }, { "isoform_ac": "A0A8V0YVW8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP53/entry#A0A8V0YVW8-1", "sequence": { "sequence": "MTTDTRISSALLSHFFQLNSSSDGQGHLRVKLKEEIAQVFAEIEGFQNAEERQEADQNPGERSSKLSQRDKLLSVGRKKFNMDPEKGIQYLIEQQLLSSDLQEIAKFLHKGEGLNKTAIGDYLGGRDSKNIQILQAFVACHQFANLNLVQALRQFLWSFRLPGEAQKIDRMMEAFANWYCKCNPGVFQSTDTCYILSFSIIMLNTSLHNPNVKDKPPFERFVSINRGINDGADLPEELLKNLFDSIKNEPFSIPEDDGNDLTHTFFNPNREGWLLKLGGRVKTWKRRWFILTDNCLYYFEYTTDKEPLGIIPLENLSVRKVDDPKKPNCFELFNPNCKGQKIKACKTDGDGKVVEGKHQSYKISAATPAERDEWIEAIRTSITQNPFYDLVSARKKKIANKN", "length": 402, "header": "tr|A0A8V0YVW8-1|A0A8V0YVW8_CHICK Computationally mapped isoform of Cytohesin 4 OS=Gallus gallus OX=9031 GN=CYTH4 PE=4 SV=1 CANONICAL=A0A8V0YP53-1" }, "locus": { "chromosome": "1", "start_pos": 51437696, "end_pos": 51426896, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034856.1", "url": "https://www.ensembl.org/id/ENSGALT00010034856.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020413.1", "url": "https://www.ensembl.org/id/ENSGALP00010020413.1" } ] } }, { "isoform_ac": "A0A8V0YVX3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP53/entry#A0A8V0YVX3-1", "sequence": { "sequence": "MDFCPAGSSDLSEAEEAEIETIRQHREELLEDIKLKEEIAQVFAEIEGFQNAEERQEADQNPGERSSKLSQRDKLLSVGRKKFNMDPEKGIQYLIEQQLLSSDLQEIAKFLHKGEGLNKTAIGDYLGGRDSKNIQILQAFVACHQFANLNLVQALRQFLWSFRLPGEAQKIDRMMEAFANWYCKCNPGVFQSTDTCYILSFSIIMLNTSLHNPNVKDKPPFERFVSINRGINDGADLPEELLKNLFDSIKNEPFSIPEDDGNDLTHTFFNPNREGWLLKLGGRVKTWKRRWFILTDNCLYYFEYTTDKEPLGIIPLENLSVRKVDDPKKPNCFELFNPNCKGQKIKACKTDGDGKVVEGKHQSYKISAATPAERDEWIEAIRTSITQNPFYDLVSARKKKIANKN", "length": 405, "header": "tr|A0A8V0YVX3-1|A0A8V0YVX3_CHICK Computationally mapped isoform of Cytohesin 4 OS=Gallus gallus OX=9031 GN=CYTH4 PE=4 SV=1 CANONICAL=A0A8V0YP53-1" }, "locus": { "chromosome": "1", "start_pos": 51444930, "end_pos": 51426896, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034868.1", "url": "https://www.ensembl.org/id/ENSGALT00010034868.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020418.1", "url": "https://www.ensembl.org/id/ENSGALP00010020418.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YP53", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP53" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "lipid binding", "id": "GO:0008289", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008289", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YP53", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP53" } ], "pmid": "" }, { "name": "guanyl-nucleotide exchange factor activity", "id": "GO:0005085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005085", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YP53", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP53" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "vesicle-mediated transport", "id": "GO:0016192", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016192", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YP53", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP53" } ], "pmid": "" }, { "name": "regulation of ARF protein signal transduction", "id": "GO:0032012", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032012", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YP53", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP53" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 144, "end_pos": 146, "annotation": "n_glycosylation_sequon" }, { "start_pos": 233, "end_pos": 235, "annotation": "n_glycosylation_sequon" }, { "start_pos": 344, "end_pos": 346, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YP53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP53" }, { "id": "PS50003", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50003" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PH", "eco_id": "ECO_0000259", "start_pos": 296, "end_pos": 412, "start_aa": "Asn", "end_aa": "Thr", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0YP53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP53" }, { "id": "PS50190", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50190" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SEC7", "eco_id": "ECO_0000259", "start_pos": 91, "end_pos": 278, "start_aa": "Arg", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 144, "end_pos": 146 }, { "start_pos": 233, "end_pos": 235 }, { "start_pos": 344, "end_pos": 346 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YP65-1", "uniprot_ac": "A0A8V0YP65", "uniprot_id": "A0A8V0YP65_CHICK", "mass": { "chemical_mass": 216079.0, "monoisotopic_mass": 216079.0 }, "refseq": { "ac": "XP_417721", "name": "zinc finger protein Rlf isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_417721" }, "gene_names": [ { "name": "RLF", "type": "recommended", "evidence": [ { "id": "A0A8V0YP65", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP65" } ] }, { "name": "RLF", "type": "synonym", "evidence": [ { "id": "XP_417721", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_417721" } ] } ], "protein_names": [ { "name": "RLF zinc finger", "type": "synonym", "evidence": [ { "id": "A0A8V0YP65", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP65/entry#names_and_taxonomy" } ] }, { "name": "zinc finger protein Rlf isoform X1", "type": "synonym", "evidence": [ { "id": "XP_417721", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_417721" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052554.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_417721.4. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_417721", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_417721" } ] }, { "annotation": "May be involved in transcriptional regulation.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YP65", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP65#function" }, { "database": "UniProtKB", "id": "ARBA00003767", "url": "https://www.uniprot.org/uniprotkb/ARBA00003767#function" }, { "database": "UniProtKB", "id": "F1ND57", "url": "https://www.uniprot.org/uniprotkb/F1ND57#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YP65", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP65" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RLF", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP65", "locus": { "chromosome": "23", "start_pos": 2111064, "end_pos": 2141514, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013981", "url": "https://www.ensembl.org/id/ENSGALG00010013981" } ] } } ], "crossref": [ { "id": "ENSGALG00000000862", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000000862", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "419573", "url": "https://www.ncbi.nlm.nih.gov/gene/419573", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052251", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052251", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057986", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057986", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR058902", "url": "https://www.ebi.ac.uk/interpro/entry/IPR058902", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "SMFQHRY", "url": "https://omabrowser.org/oma/group/SMFQHRY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YP65", "url": "https://www.orthodb.org/?gene=A0A8V0YP65", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1ND57", "url": "https://www.orthodb.org/?gene=F1ND57", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15507", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15507", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15507:SF18", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15507:SF18", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25420", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25420", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25580", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25580", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF26218", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF26218", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_417721", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_417721", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YP65", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP65", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YP65-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP65-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1ND57", "url": "https://www.uniprot.org/uniprotkb/F1ND57", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1ND57-1", "url": "https://www.uniprot.org/uniprotkb/F1ND57-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MARLVAALRGRLWQLQTELCEQEVSEASSRAYCRGFCQTLLHYAGSRGASEHILPFLEVYRISIQSFANARPYLTTECEDVLLVLGRLVLSCFELLLSIPESELPHEVWLEFHQSIQDSHDALLEFGNNNLQVLVDITREGVWKNPVLMKILSQQPVETEEANKLITREGPSFLQMRIKHLMKSNCIPQATFLSKLCADCPDIANVASFRQAYITCVCSMLPNEDSIKEIAKVDCKEVLDIICNLESEGQENTAFILCTTYLTHQLQTANVYCSWELTLFWSKLQRRIDPSLDSFLERCRQFGIIAKTLQHLFFLIRVIQSEAEEAGLAVSVLLCVRALQIRSNGSDEMKTSVCKTIACLLPEDLEVRRACQLTEFLLEPTLSGFNMLEELYMQPDQKFDEENALVPNSLRCELLLALKAYWPFDPEFWDWKTLKRHCLKLLGKAGSDSEDDASCNMSINETDMLETFFSDCDEAKDHKYYDGKDPINYHKEKARVKKPIGSSERYQRWLQYKFFCVLCKRECIEARILHHSKMHMEDGIYTCPVCTKKFKRKEFFVPHVMEHVKMPPSRTHRPKKKIILKKERSPQKTTASSSPTPTLQEKSHQPELSEAFGNDAHEYVTFSQLENCQLQDRDIYPCPGTDCSRVFKQFKYLSVHLKAEHQNNDENAKHYLDMKNRREKCAFCRRHFMTSFHLREHERVHCGPQPYMCVSMDCYARFGSVNELLNHKQTHDDLRYKCELNGCNIVFSDLGQLYHHEAQHFRDASYTCNFFGCKKFYYSKTEFQNHLAVHNIAVSNGEVKQTVKLEESQLLEQSENSHQNETLDPTGSEEIPQIKEEALSDSEDLDSESNCSLHCGNHSGTAAVNEGKVPPLLIETLAHGQTVPSFLMSREGVFHSADVKQQCSNAAVCFDEKKFSCGFEGCCSAHKNSRSVHKHLRRAHPYNFKGKKGMEVKTKDFLDVLSDAPESQSPTDISTEFGHKSDRNTDSPESSYCNVNAKGNNSFKEETYPSSPETSFYDSSKESSIEDNMLELMLGLKHLSLKNSNIQSSSRSKRVLGSLQSCSSRDTKCPESGVDATTSKFKFQEQQDNLPSQYLTQLAAKPFFCECQGCTCEFVTREALLMHYVKKHNYSKEMVLQLNMFQHRYSPFKCHICQRSFTRKTHLRIHYRNKHQIGCEQVAHKVCSNEKFDHVGLCTDDVHKNSAVPTPVCPTKVEFIDRSEQRCHPKKEECSSETDLESSEETDGNITRKSSKIATLDSHREELEAREGRGSKRTVAKGNLCYILHKYHKPFHCIHKSCNSAFTNQKGLIRHYRTVHQYNKEQLCLEKDKARTKRELVKCKKIFACKHKECGKRFFCSKDLAKHCSDFHNEHLDDQKLLAGTESARFACNQAQCPAVFCTFSKLKQHLIEEHASGERINKDFEIHCDLNGCNRIFTNYSHYSQHVYFRHSEYYDDLFGNQKEEQDNHDKNKSGQSCVRGGFGLNKQNGKRVKDKPKRTNRSKEKHLLSFKTKEEALQMCQENSNQTQYPCMVVGCLSVVKLESSILRHYKRTHQMTNMYIEQRIQKLVLCVKCGTMTEKQSCSEPALDLDKKDVEVKEEKSADPERPQEAEKSPVSNTDCQHQDVSSEEQKRCPPSSESFDPSAFTYSGTLNCSHGPKSSCSEEHNVRESVIGNSEELSENSERENSSYFSSLQLELPREKDAEGCEHSAVNQNAKRNVLFATKDKFQKPPVSRPFDLKTYKPMGFESSFLKFIQESEGKDDDDDDFDEVVEWESPEQLPVDRALQQEGEAQKDSPLNSCASDKSVVIPQSDPGQLTEMQPLLAEPSSAPSLENLRAILDKALTGCGDLALKQLHYLRPVVVLERSKFSTALIDLFPTKKADELCVGSM", "length": 1888, "header": "tr|A0A8V0YP65-1|A0A8V0YP65_CHICK Isoform 1 of RLF zinc finger OS=Gallus gallus OX=9031 GN=RLF PE=3 SV=1 CANONICAL=A0A8V0YP65-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YP65-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP65/entry#A0A8V0YP65-1", "sequence": { "sequence": "MARLVAALRGRLWQLQTELCEQEVSEASSRAYCRGFCQTLLHYAGSRGASEHILPFLEVYRISIQSFANARPYLTTECEDVLLVLGRLVLSCFELLLSIPESELPHEVWLEFHQSIQDSHDALLEFGNNNLQVLVDITREGVWKNPVLMKILSQQPVETEEANKLITREGPSFLQMRIKHLMKSNCIPQATFLSKLCADCPDIANVASFRQAYITCVCSMLPNEDSIKEIAKVDCKEVLDIICNLESEGQENTAFILCTTYLTHQLQTANVYCSWELTLFWSKLQRRIDPSLDSFLERCRQFGIIAKTLQHLFFLIRVIQSEAEEAGLAVSVLLCVRALQIRSNGSDEMKTSVCKTIACLLPEDLEVRRACQLTEFLLEPTLSGFNMLEELYMQPDQKFDEENALVPNSLRCELLLALKAYWPFDPEFWDWKTLKRHCLKLLGKAGSDSEDDASCNMSINETDMLETFFSDCDEAKDHKYYDGKDPINYHKEKARVKKPIGSSERYQRWLQYKFFCVLCKRECIEARILHHSKMHMEDGIYTCPVCTKKFKRKEFFVPHVMEHVKMPPSRTHRPKKKIILKKERSPQKTTASSSPTPTLQEKSHQPELSEAFGNDAHEYVTFSQLENCQLQDRDIYPCPGTDCSRVFKQFKYLSVHLKAEHQNNDENAKHYLDMKNRREKCAFCRRHFMTSFHLREHERVHCGPQPYMCVSMDCYARFGSVNELLNHKQTHDDLRYKCELNGCNIVFSDLGQLYHHEAQHFRDASYTCNFFGCKKFYYSKTEFQNHLAVHNIAVSNGEVKQTVKLEESQLLEQSENSHQNETLDPTGSEEIPQIKEEALSDSEDLDSESNCSLHCGNHSGTAAVNEGKVPPLLIETLAHGQTVPSFLMSREGVFHSADVKQQCSNAAVCFDEKKFSCGFEGCCSAHKNSRSVHKHLRRAHPYNFKGKKGMEVKTKDFLDVLSDAPESQSPTDISTEFGHKSDRNTDSPESSYCNVNAKGNNSFKEETYPSSPETSFYDSSKESSIEDNMLELMLGLKHLSLKNSNIQSSSRSKRVLGSLQSCSSRDTKCPESGVDATTSKFKFQEQQDNLPSQYLTQLAAKPFFCECQGCTCEFVTREALLMHYVKKHNYSKEMVLQLNMFQHRYSPFKCHICQRSFTRKTHLRIHYRNKHQIGCEQVAHKVCSNEKFDHVGLCTDDVHKNSAVPTPVCPTKVEFIDRSEQRCHPKKEECSSETDLESSEETDGNITRKSSKIATLDSHREELEAREGRGSKRTVAKGNLCYILHKYHKPFHCIHKSCNSAFTNQKGLIRHYRTVHQYNKEQLCLEKDKARTKRELVKCKKIFACKHKECGKRFFCSKDLAKHCSDFHNEHLDDQKLLAGTESARFACNQAQCPAVFCTFSKLKQHLIEEHASGERINKDFEIHCDLNGCNRIFTNYSHYSQHVYFRHSEYYDDLFGNQKEEQDNHDKNKSGQSCVRGGFGLNKQNGKRVKDKPKRTNRSKEKHLLSFKTKEEALQMCQENSNQTQYPCMVVGCLSVVKLESSILRHYKRTHQMTNMYIEQRIQKLVLCVKCGTMTEKQSCSEPALDLDKKDVEVKEEKSADPERPQEAEKSPVSNTDCQHQDVSSEEQKRCPPSSESFDPSAFTYSGTLNCSHGPKSSCSEEHNVRESVIGNSEELSENSERENSSYFSSLQLELPREKDAEGCEHSAVNQNAKRNVLFATKDKFQKPPVSRPFDLKTYKPMGFESSFLKFIQESEGKDDDDDDFDEVVEWESPEQLPVDRALQQEGEAQKDSPLNSCASDKSVVIPQSDPGQLTEMQPLLAEPSSAPSLENLRAILDKALTGCGDLALKQLHYLRPVVVLERSKFSTALIDLFPTKKADELCVGSM", "length": 1888, "header": "tr|A0A8V0YP65-1|A0A8V0YP65_CHICK Isoform 1 of RLF zinc finger OS=Gallus gallus OX=9031 GN=RLF PE=3 SV=1 CANONICAL=A0A8V0YP65-1" }, "locus": { "chromosome": "23", "start_pos": 2141418, "end_pos": 2112068, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033528.1", "url": "https://www.ensembl.org/id/ENSGALT00010033528.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019769.1", "url": "https://www.ensembl.org/id/ENSGALP00010019769.1" } ] } }, { "isoform_ac": "F1ND57-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP65/entry#F1ND57-1", "sequence": { "sequence": "MLLLSKISLSSVFQVTESQIKCTFFLDSHDALLEFGNNNLQVLVDITREGVWKNPVLMKILSQQPVETEEANKLITREGPSFLQMRIKHLMKSNCIPQATFLSKLCADCPDIANVASFRQAYITCVCSMLPNEDSIKEIAKVDCKEVLDIICNLESEGQENTAFILCTTYLTHQLQTANVYCSWELTLFWSKLQRRIDPSLDSFLERCRQFGIIAKTLQHLFFLIRVIQSEAEEAGLAVSVLLCVRALQIRSNGSDEMKTSVCKTIACLLPEDLEVRRACQLTEFLLEPTLSGFNMLEELYMQPDQKFDEENALVPNSLRCELLLALKAYWPFDPEFWDWKTLKRHCLKLLGKAGSDSEDDASCNMSINETDMLETFFSDCDEAKDHKYYDGKDPINYHKEKARVKKPIGSSERYQRWLQYKFFCVLCKRECIEARILHHSKMHMEDGIYTCPVCTKKFKRKEFFVPHVMEHVKMPPSRTHRPKKKIILKKERSPQKTTASSSPTPTLQEKSHQPELSEAFGNDAHEYVTFSQLENCQLQDRDIYPCPGTDCSRVFKQFKYLSVHLKAEHQNNDENAKHYLDMKNRREKCAFCRRHFMTSFHLREHERVHCGPQPYMCVSMDCYARFGSVNELLNHKQTHDDLRYKCELNGCNIVFSDLGQLYHHEAQHFRDASYTCNFFGCKKFYYSKTEFQNHLAVHNIAVSNGEVKQTVKLEESQLLEQSENSHQNETLDPTGSEEIPQIKEEALSDSEDLDSESNCSLHCGNHSGTAAVNEGKVPPLLIETLAHGQTVPSFLMSREGVFHSADVKQQCSNAAVCFDEKKFSCGFEGCCSAHKNSRSVHKHLRRAHPYNFKGKKGMEVKTKDFLDVLSDAPESQSPTDISTEFGHKSDRNTDSPESSYCNVNAKGNNSFKEETYPSSPETSFYDSSKESSIEDNMLELMLGLKHLSLKNSNIQSSSRSKRVLGSLQSCSSRDTKCPESGVDATTSKFKFQEQQDNLPSQYLTQLAAKPFFCECQGCTCEFVTREALLMHYVKKHNYSKEMVLQLNMFQHRYSPFKCHICQRSFTRKTHLRIHYRNKHQIGCEQVAHKVCSNEKFDHVGLCTDDVHKNSAVPTPVCPTKVEFIDRSEQRCHPKKEECSSETDLESSEETDGNITRKSSKIATLDSHREELEAREGRGSKRTVAKGNLCYILHKYHKPFHCIHKSCNSAFTNQKGLIRHYRTVHQYNKEQLCLEKDKARTKRELVKCKKIFACKHKECGKRFFCSKDLAKHCSDFHNEHLDDQKLLAGTESARFACNQAQCPAVFCTFSKLKQHLIEEHASGERINKDFEIHCDLNGCNRIFTNYSHYSQHVYFRHSEYYDDLFGNQKEEQDNHDKNKSGQSCVRGGFGLNKQNGKRVKDKPKRTNRSKEKHLLSFKTKEEALQMCQENSNQTQYPCMVVGCLSVVKLESSILRHYKRTHQMTNMYIEQRIQKLVLCVKCGTMTEKQSCSEPALDLDKKDVEVKEEKSADPERPQEAEKSPVSNTDCQHQDVSSEEQKRCPPSSESFDPSAFTYSGTLNCSHGPKSSCSEEHNVRESVIGNSEELSENSERENSSYFSSLQLELPREKDAEGCEHSAVNQNAKRNVLFATKDKFQKPPVSRPFDLKTYKPMGFESSFLKFIQESEGKDDDDDDFDEVVEWESPEQLPVDRALQQEGEAQKDSPLNSCASDKSVVIPQSDPGQLTEMQPLLAEPSSAPSLENLRAILDKALTGCGDLALKQLHYLRPVVVLERSKFSTALIDLFPTKKADELCVGSM", "length": 1797, "header": "tr|F1ND57-1|F1ND57_CHICK Computationally mapped isoform of RLF zinc finger OS=Gallus gallus OX=9031 GN=RLF PE=3 SV=4 CANONICAL=A0A8V0YP65-1" }, "locus": { "chromosome": "23", "start_pos": 2129368, "end_pos": 2112068, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033523.1", "url": "https://www.ensembl.org/id/ENSGALT00010033523.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019767.1", "url": "https://www.ensembl.org/id/ENSGALP00010019767.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1206, "start_aa": "Thr", "end_pos": 1206, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1206", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 596, "start_aa": "Thr", "end_pos": 596, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr596", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2LLX4-1", "protein_name": "Zinc finger protein Rlf isoform X1", "gene_name": "Rlf", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MADGKGDATAAAGAGAGVEAPAVAGAGAGTETESMPRGHRPASPASGASGLRPCLWQLETELREQEVSEVSSLNYCRSFCQTLLQYASNKNASEHIVYLLEVYRLAIQSFASARPFLTTECEDVLLVLGRLVLSCFELLLSVPESELPCEVWVPFLQSLQESHDALLEFGNNNLQILVHVTKEGVWKNPVLLKILSQQPVETEEVNKLIAQEGPSFLQMRIKHLLKSNCIPQATALSKLCAESKELSQVSCFQQAYVTCLCSMLPSEEAIQEIAKVDCKEVLDIICNLESEGQDNTAFVLCTTYLTQQLQTASVYCSWELTLFWSKLQRRIDPSLETFLERCRQFGVIAKTQQHLFCLIRVIQTEAQDAGIGVSILLCVRALQLRSSEDEEMKASVCKTISCLLPEDLEVRRACQLTEFLIEPSLDGFNMLEELYLQPDQKFDEENAPVPNSLRCELLLALKAHWPFDPEFWDWKTLKRHCHQLLGQEASDSDDDLSGYEMSINDTDVLESFLSDYDESKEDKQYRRNLADQNKEKRDKKPIGSSERYQRWLQYKFFCLLCKRECIEARILHHSKMHMEDGIYTCPVCIKKFKRKELFVPHVMEHVKMPPSRRDRSRKKLLLKGSQRGIYPKSPTGSLEQNQSLSEQAKGESHEYVTFSKLEDRRLQDRDLYPCPGTDCSRVFKQFKYLSVHLKAEHQNNDENAKHYLDMKNRREKCTYCRRHFMSAFHLREHEQVHCGPQPYMCVSIDCYARFGSVNELLNHKQKHDDLRYKCELNGCNIVFSDLGQLYHHEAQHFRDASYTCNVVGCKKFYYSKIEYQNHLSMHNVESPDGELKKSVKLEEPAAGGKQDCVDQTHLLDQTDKSHSPEDHLFCAGSATAHIDTPENLKDNSDSNSSDQLSHSSSTSINEELIDTLDHSETMQDLLLSHEKVFVPSSLKEKCSNVAICFDGTKFTCGFDGCGSTYKNARGMQKHLRKVHPYHCKSRKVKTKDLFTCLGDKHNQADKFDAEPKPSSDTNSDSPDEGLDHSIHAKCKRDHRSYSPEPSICASKRPCTEDTMLELLLRLKHLSLKNSFSGSLQGCPSSGAKSLQSVPSSMSDLNLQNQDENMPSQYLAQLAAKPFFCELQGCKYEFVTREALLMHYLKKHNYSKEKVLQLTMFQHRYSPFRCHICQRSFTRKTHLRIHYKNKHQIGSDRATHRLLESEKCDHEGPCSVDRLKGDCSAELGPNSNSEMTQCHSKKDECSSETDLESSCEETESKVSGISSPIGSHREEGEGREGRGSRRTVAKGNLCYILNKYHKPFHCIHKTCNSSFTNLKGLIRHYRTVHQYNKEQLCLEKDKARTKRELVKCKKLFACKYKDCNKRFLCSKALAKHCSDSHNLDHIEESKVLSETESAARFSCNQPQCPAVFYSFSKLKQHLLEQHNIEGEIHSDYEIHCTLNGCGQIFSHRSNYFQHVYYRHKDSYDNLFSNQKVANERLLRSEKVCQTAEAQEQTQTEGQTQGQEQEQQTAKRPFNTKAKKCGLLKDKKAPISFKTRAEAIHMCVEHSEHTQYPCMVQGCMSVVKLESSIVRHYKRTHQMNSAYLEQQLENLVVCVKYGTKIKEEPPSEVEPCVKKEENTSCESVHTEHSPGDSSVPLQNADSTCPAQQDGDQKGCVERNSVLDADTLLYRGTLKCNHTSETTSLEQCDTVQSPPCKIESPIPNPSGTESSTYFTDFQLPLSRIKEEPGQHSSGQENTVKSATQVPKDNMRKHPQPRSFDLKTYKPMGFESSFLKFIQESEEKDDDFDDWEPSEHLPLNNSSQPANDLTGNVVANTVVNDSDPQVDIPHSSINPPVAENLTAVPPLVVAEAAAVPSLENLRVVLDKALTDCGELALKQLHYLRPVVVLERSKFSTPILDLFPTKKTDELCVGSS", "length": 1915 }, "evidence": [ { "id": "A0A8V0YP65", "url": "https://omabrowser.org/oma/group/A0A8V0YP65/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A2A7F4-1", "protein_name": "Rearranged L-myc fusion sequence", "gene_name": "Rlf", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MADGKGDATAAAGAGAGAEAPAVAGAEVETESMARGHRPASPASGAPGLRPCLWQLETELREQEVSEVSSLSYCRSFCQTLLQYASNKNASEHIVYLLEVYRLAIQSFASARPFLTTECEDVLLVLGRLVLSCFELLLSVSESELPCEVWVPFLQSLQESHDALLEFGNNNLQILVHVTKEGVWKNPILLKILSQQPVETEEVNKLIAQEGPSFLQMRIKHLLKSNCIPQATALSKLCAESKELAQVSCFQQAYITCLCSMLPSEEAIQEIAKVDCKDVLDIICNLESEGQDNTAFVLCTTYLTQQLQTASVYCSWELTLFWSKLQRRIDPSLETFLERCRQFGVIAKTQQHLFCLIRVIQTEAQDAGIGVSILLCVRALQLRSSEDEEMKASVCKTISCLLPEDLEVRRACQLTEFLIEPSLDGFNMLEELYLQPDQKFDEENAPVPNSLRCELLLALKAHWPFDPEFWDWKTLKRHCHQLLGQEASDSDDDLSGYEMSINDTDVLESFLSDYDDGKEDKQYRRSLTDQNKEKRDKKPIGSSERYQRWLQYKFFCLLCKRECIEARILHHSKMHMEDGIYTCPVCIKKFKRKELFVPHVMEHVKMPPSRSHRSRKKLLLKSAQRGIYPKSPTGSLEQNPEQARGESHEYVTFSKLEDRRLQDRDLYPCPGTDCSRVFKQFKYLSVHLKAEHQNNDENAKHYLDMKNRREKCTYCRRHFMSAFHLREHEQVHCGPQPYMCVSIDCYARFGSVNELLNHKQKHDDLRYKCELNGCNIVFSDLGQLYHHEAQHFRDASYTCNVLGCKKFYYSKIEYQNHLSMHNVESPDGELKKSVKLEEPGAGGKQDCVDQSHLLDETEKSHSLEDHHLCPGSASAHIDTTETLKDNSDSNSSDQLSHSSSTSITEELIDTLDHSETMQDLLLSHEKVFVPSSLKDKCSNVAVCFDGTKFTCGFDGCGSTYKNARGMQKHLRKVHPYHCKPRKIKTKDLFNCLDDKHNEADKFDAEPKPSSDTNSDSPDEGPDHSIHTKCKREHQGYSPEPSICASKRPCTEDTMLELLLRLKHLSLKNSIAHGSFSGSLQGCPSSGAKSLQSVPSSISDVNLQNQDENMPSQYLAQLAAKPFFCELQGCKYEFVTREALLMHYLKKHNYSKEKVLQLTMFQHRYSPFRCHICQRSFTRKTHLRIHYKNKHQIGSDRATHRLLDSEKCDHEGPCSVDRLKGDCSTELGPNSNSETTQCHSKKDECSSETDLESSCEETESKISGISSPIGSHREEGEEKEGRGSRRTVAKGNLCYILNKYHKPFHCIHKTCNSSFTNLKGLIRHYRTVHQYNKEQLCLEKDKARTKRELVKCKKLFACKYKDCNKRFLCSKALAKHCSDSHNLDHIEESKVLSETESAARFSCNQPQCPAVFYSFSKLKHHLLEQHNIEGEIHSDYEIHCTLNGCGQIFSHRSNYFQHVYYRHKDYYDNLFSSQKVANERLLRSEKVCQTTQAQGLTQTQGQTQGQTQGQEQQAAKRPFNTKAKKCGLLKDKKAPITFKTRAEAIHMCVEHSEHTQYPCMVQGCLSVVKLESSIVRHYKRTHQMNSAYLEQQLENLVVCVKYGTKIKDEPPSEVEPCVKKEESTSCESVHTENGAPGDSSVPLPNTDSTCPAEQDVGQKGCSERNPVFDTHSLLYRGTLKCNHSSETTSLEQCNIAQSSPCKIESPIPNPSGTESGTYFTDFQLPLPRIKEEPGQHSSGQENTVKNATQVPKENIRKHSQPRSFDLKTYKPMGFESSFLKFIQESEEKDDDFDDWEPSEHLTLNNSSHPSNDLTGNVVADTIVNESAPQVDIPHSSSDPPVSENLTAVPPLVVAEATAVPSLENLRVVLDKALTDCGELALKQLHYLRPVVVLERSKFSTPILDLFPTKKTDELCVGSS", "length": 1918 }, "evidence": [ { "id": "A0A8V0YP65", "url": "https://omabrowser.org/oma/group/A0A8V0YP65/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3ZJX1-1", "protein_name": "RLF zinc finger", "gene_name": "Rlf", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MADGKGDATAAAGAGAGAEAAAAAGAGTETESMARGHRPASPASGAPGLRPCLWQLETELREQEVSEVSSLNYCRSFCQTLLQYASNKNASEHIVYLLEVYRLAIQSFASARPFLTTECEDVLLVLGRLVLSCFELLLSVSESELPCEVWVPFLQSLQESHDALLEFGNNNLQILVHVTKEGVWKNPVLLKILSQQPVETEEVNKLIAQEGPSFLQMRIKHLLKSNCIPQATALSKLCAESKELAQVSCFQQAYVTCLCSMLPSEEAIQEIAKVDCKEVLDIICNLESEGQDNTAFVLCTTYLTQQLQTASVYCSWELTLFWSKLQRRTDPSLETFLERCRQFGVIAKTQQHLFCLIRVIQTEAQDAGIGVSILLCVRALQLRSSEDEEMKASVCKTISCLLPEDLEVRRACQLTEFLIEPSLDGFNMLEELYLQPDQKFDEENAPVPNSLRCELLLALKAHWPFDPEFWDWKTLKRHCHQLLGQEASDSDDDLSGYEMSINDTDVLESFLSDYDEGKEDKQYRRSLADQNKEKRDKKPIGSSERYQRWLQYKFFCLLCKRECIEARILHHSKMHMEDGVYTCPVCIKKFKRKELFVPHVMEHVKMPPSRSHRSRKKLLLKSSQSGIYPKSPTGSLEQNPSLSEQARGESHEYVTFSKLEDRRLQDRDLYPCPGTDCSRVFKQFKYLSVHLKAEHQNNDENAKHYLDMKNRREKCTYCRRHFMSAFHLREHEQVHCGPQPYMCVSIDCYARFGSVNELLNHKQKHDDLRYKCELNGCNIVFSDLGQLYHHEAQHFRDASYTCNVLGCKKFYYSKIEYQNHLSMHNVENPDGELKKSVKLEEPVAGEKQDCVDQSHLLEQTDKSHSPEDLLFCPGSASAHIDTTETLKDNSDSNSSDQLSPSSSTSITEELIDSLDHSETMQDLLLSDEKVFVPSSLKEKCSNVAVCFDGTKFTCGFDGCGSTYKNARGMQKHLRKVHPYHCKPRKIKTKDLFTCLDDKHNEADKFDAEPKPSSDTNSDSLDEGPDHSIHAKCKREHQGYSPEPSICASKRPCTEDTMLELLLRLKHLSLKNSIAHGSFSGSLQGCPSSGAKSLQSVPSSISDLNLQNQDENMPSQYLAQLAAKPFFCELQGCKYEFVTREALLMHYLKKHNYSKEKVLQLTMFQHRYSPFRCHICQRSFTRKTHLRIHYKNKHQIGSDRATHRLLDSEKCDHEGPCSVDRLTGDCSAELGPNSSSETTQCHSKKDECSSETDLESSCEETESKMCGISSPTGSHREEGEGKEGRGSRRTVAKGNLCYILNKYHKPFHCIHKTCNSSFTNLKGLIRHYRTVHQYNKEQLCLEKDKARTKRELVKCKKLFACKYKDCNKRFLCSKALAKHCSDSHNLDHIEESKVLSETESAARFSCNQPQCPAVFYSFSKLKHHLLEQHNIEGEIHSDYEIHCTLNGCGQIFSHRSNYFQHVYYRHKDYYDNLFSSQKVANERLLRSEKVCQTTQAQGLTQGQGQTQTQGQEQQAAKRPFNTKAKKCGLLKDKKAPISFKTRAEAIHMCVEHSEHTQYPCMVQGCLSVVKLESSIVRHYKRTHQMNSAYLEQQLENLVVCVKYGTKIKDEPPSEVEPCVKKEENASCESVRTESQSPGDSSVPLPNTDSTCPAEQDGGQKGCSERNPVFDTHSLLYRGTLKCNHSSETTSLEQCNIVQSPPCKIESPVANPSGTESGTYFTDFQLPLPRIKEEPGQHSSGQENTVKNATQVPKENIRKHSQPRSFDLKTYKPMGFESSFLKFIQESEEKDDDFDDWEPSEHLTLNNSSQPGNDLTGNVVADTIVNDSDPQVDIPHSSSDPAVPENLTAIPPLVVAEATAVPSLENLRVVLDKALTDCGELALKQLHYLRPVVVLERSKFSTPILDLFPTKKTDELCVGSS", "length": 1919 }, "evidence": [ { "id": "A0A8V0YP65", "url": "https://omabrowser.org/oma/group/A0A8V0YP65/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E1BAS5-1", "protein_name": "RLF zinc finger", "gene_name": "RLF", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MADGKGDAAATAGAGAEAPVGAGAGDGTETESMARGHSPASPAPVASGLRPCLWQLETELREQEVSEVSSLNYCRSFCQTLLQYASNKNASEHIVYLLEVYRLAIRSFASARPYLTTECEDVLLVLGRLVLSCFELLLSVSESELPCEAWVLFLQSLQESHDALLEFGNNNLQILVHVTKEGVWKNPVLLKILSQQPVETEEVNKLIAQEGPFFLQMRIKHLLKSNCIPQATALSKLCAESKEISNVSSFQQAYITCLCSILPNEDAIKEIAKVDCKEILDIICNLESEGQDNTAFVLCTTYLTQQLQTASVYCSWELTLFWSKLQRRIDPSVDTFLERCRQFGVIAKTQQHLFCLIRVIQTEAQDAGLGVSILLCVRALQLRTSEDEEMKASVCKTIACLLPEDLEVRRACQLTEFLIEPSLDGFNMLEELYSQPDQKFDEENAPVPNSLRCELLLALKAHWPFDPEFWDWKTLKRHCHQLLGQEASDSDDDLSGYEMSINDTDVLESFLSDYEEGKEDKQYRRRDVTDQHKEKRDKKPIGSSERYQRWLQYKFFCLLCKRECIEARILHHSKMHMEDGIYTCPVCIKKFKRKEIFVPHVMEHVKMPPSRRDRSRKKLLLKGSQKGICPKSPSAALEQGQSLNEQAKGESHEYVTFSKLEDCHLQDRDLYPCPGTDCSRVFKQFKYLSVHLKAEHQNNDENAKHYLDMKNRREKCTYCRRHFMSAFHLREHEQVHCGPQPYMCVSIDCYARFGSVNELLNHKQKHDDLRYKCELNGCNIVFSDLGQLYHHEAQHFRDASYTCNFVGCKKFYYSKIEYQNHLSMHNVESSNGDVKKTVKLEPAAGEKQDCIDQPHLLDQTDKSRLPEDLLFCAGSASSQIETTENLKENSDSNSSDQLSHSSSASMNEELIDTLDHSETMQDILLSHEKVFVPSSLKEKCSNVAVCFDGTKFTCGFDGCGSTYKNARGMQKHLRKVHPYHFKPKKVKTKDLFPCLGNEHNPTTEKFDAEPKPSSDTNSDSPDEGLDHNIHTKCKREHQGYSSEASICASKRPCTEDTMLELLLRLKHLSLKNSITHGSFSGSLQGYPSSGAKSLQAVSATISDLNFQNQDENMPSQYLAQLAAKPFFCELQGCKYEFVTREALLMHYLKKHNYSKEKVLQLTMFQHRYSPFQCHICQRSFTRKTHLRIHYKNKHQIGSDRVTQKLLDNEKCDHEGPCSVDRLKVDCPSELGGDPSGNSEKPHCHSKKDECSSETDLESSCEETESKISDLSSPIGSHREEGEGREGRGSRRTVAKGNLCYILNKYHKPFHCIHKTCNSSFTNLKGLIRHYRTVHQYNKEQLCLEKDKARTKRELVKCKKIFACKYKECNKRFLCSKALAKHCSDSHNLDHIEEPKVLSEAESVARFSCNQPQCPAVFYTFSKLKHHLMEQHNIEGEIHSDYEIHCDLNGCGQIFTHRSNYSQHVYYRHKDYYDDLFRSQKVANERLLRSEKVCQTAHPQGHEHQTTRKSFNAKAKKCGLIKDKKAPISFKTRAEALHMCVEHSEHTQYPCMVQGCLSVVKLESSIVRHYKRTHQMSSAYLEQQMENLVMCVKYGTKIKEEPISEAEPYIKKEEDGSCESELIQHSHPPADTSMPVQTADPLHPGERDGGQKGCIESNPVFDADSLLYRGTLKCNHSSETTSLEQCNIVQPPPCKIENSIPNPDGTESGTYFTSFQLPLPRIKDSETGQQSSGQENTVKNSTHVPKENFRKHPQPRSFDLKTYKPMGFESSFLKFIQESEEKEDDFDDWEPSEHLTLSNSSQPCNDLTGSVMANNMVNDNDPEVDIPHSSSDSAIHENLTAIPPLIVAETTTVPSLENLRVVLDKALTDCGELALKQLHYLRPVVVLERSKFSTPILDLFPTKKTDELCVGSS", "length": 1912 }, "evidence": [ { "id": "A0A8V0YP65", "url": "https://omabrowser.org/oma/group/A0A8V0YP65/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q13129-1", "protein_name": "Zinc finger protein Rlf", "gene_name": "RLF", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MADGKGDAAAVAGAGAEAPAVAGAGDGVETESMVRGHRPVSPAPGASGLRPCLWQLETELREQEVSEVSSLNYCRSFCQTLLQYASNKNASEHIVYLLEVYRLAIQSFASARPYLTTECEDVLLVLGRLVLSCFELLLSVSESELPCEVWLPFLQSLQESHDALLEFGNNNLQILVHVTKEGVWKNPVLLKILSQQPVETEEVNKLIAQEGPSFLQMRIKHLLKSNCIPQATALSKLCAESKEISNVSSFQQAYITCLCSMLPNEDAIKEIAKVDCKEVLDIICNLESEGQDNTAFVLCTTYLTQQLQTASVYCSWELTLFWSKLQRRIDPSLDTFLERCRQFGVIAKTQQHLFCLIRVIQTEAQDAGLGVSILLCVRALQLRSSEDEEMKASVCKTIACLLPEDLEVRRACQLTEFLIEPSLDGFNMLEELYLQPDQKFDEENAPVPNSLRCELLLALKAHWPFDPEFWDWKTLKRHCHQLLGQEASDSDDDLSGYEMSINDTDVLESFLSDYDEGKEDKQYRRRDLTDQHKEKRDKKPIGSSERYQRWLQYKFFCLLCKRECIEARILHHSKMHMEDGIYTCPVCIKKFKRKEMFVPHVMEHVKMPPSRRDRSKKKLLLKGSQKGICPKSPSAIPEQNHSLNDQAKGESHEYVTFSKLEDCHLQDRDLYPCPGTDCSRVFKQFKYLSVHLKAEHQNNDENAKHYLDMKNRREKCTYCRRHFMSAFHLREHEQVHCGPQPYMCVSIDCYARFGSVNELLNHKQKHDDLRYKCELNGCNIVFSDLGQLYHHEAQHFRDASYTCNFLGCKKFYYSKIEYQNHLSMHNVENSNGDIKKSVKLEESATGEKQDCINQPHLLNQTDKSHLPEDLFCAESANSQIDTETAENLKENSDSNSSDQLSHSSSASMNEELIDTLDHSETMQDVLLSNEKVFGPSSLKEKCSSMAVCFDGTKFTCGFDGCGSTYKNARGMQKHLRKVHPYHFKPKKIKTKDLFPSLGNEHNQTTEKLDAEPKPCSDTNSDSPDEGLDHNIHIKCKREHQGYSSESSICASKRPCTEDTMLELLLRLKHLSLKNSITHGSFSGSLQGYPSSGAKSLQSVSSISDLNFQNQDENMPSQYLAQLAAKPFFCELQGCKYEFVTREALLMHYLKKHNYSKEKVLQLTMFQHRYSPFQCHICQRSFTRKTHLRIHYKNKHQIGSDRATHKLLDNEKCDHEGPCSVDRLKGDCSAELGGDPSSNSEKPHCHPKKDECSSETDLESSCEETESKTSDISSPIGSHREEQEGREGRGSRRTVAKGNLCYILNKYHKPFHCIHKTCNSSFTNLKGLIRHYRTVHQYNKEQLCLEKDKARTKRELVKCKKIFACKYKECNKRFLCSKALAKHCSDSHNLDHIEEPKVLSEAGSAARFSCNQPQCPAVFYTFNKLKHHLMEQHNIEGEIHSDYEIHCDLNGCGQIFTHRSNYSQHVYYRHKDYYDDLFRSQKVANERLLRSEKVCQTADTQGHEHQTTRRSFNAKSKKCGLIKEKKAPISFKTRAEALHMCVEHSEHTQYPCMVQGCLSVVKLESSIVRHYKRTHQMSSAYLEQQMENLVVCVKYGTKIKEEPPSEADPCIKKEENRSCESERTEHSHSPGDSSAPIQNTDCCHSSERDGGQKGCIESSSVFDADTLLYRGTLKCNHSSKTTSLEQCNIVQPPPPCKIENSIPNPNGTESGTYFTSFQLPLPRIKESETRQHSSGQENTVKNPTHVPKENFRKHSQPRSFDLKTYKPMGFESSFLKFIQESEEKEDDFDDWEPSEHLTLSNSSQSSNDLTGNVVANNMVNDSEPEVDIPHSSSDSTIHENLTAIPPLIVAETTTVPSLENLRVVLDKALTDCGELALKQLHYLRPVVVLERSKFSTPILDLFPTKKTDELCVGSS", "length": 1914 }, "evidence": [ { "id": "A0A8V0YP65", "url": "https://omabrowser.org/oma/group/A0A8V0YP65/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YP65", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP65" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YP65", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP65" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YP65", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP65" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YP65", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP65" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YP65", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP65" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YP65", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP65" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1000, "end_pos": 1002, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1129, "end_pos": 1131, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1245, "end_pos": 1247, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1436, "end_pos": 1438, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1469, "end_pos": 1471, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1498, "end_pos": 1500, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1523, "end_pos": 1525, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1651, "end_pos": 1653, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1685, "end_pos": 1687, "annotation": "n_glycosylation_sequon" }, { "start_pos": 344, "end_pos": 346, "annotation": "n_glycosylation_sequon" }, { "start_pos": 456, "end_pos": 458, "annotation": "n_glycosylation_sequon" }, { "start_pos": 460, "end_pos": 462, "annotation": "n_glycosylation_sequon" }, { "start_pos": 820, "end_pos": 822, "annotation": "n_glycosylation_sequon" }, { "start_pos": 850, "end_pos": 852, "annotation": "n_glycosylation_sequon" }, { "start_pos": 857, "end_pos": 859, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YP65", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP65" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 541, "end_pos": 568, "start_aa": "Tyr", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 596, 1206 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1000, "end_pos": 1002 }, { "start_pos": 1129, "end_pos": 1131 }, { "start_pos": 1245, "end_pos": 1247 }, { "start_pos": 1436, "end_pos": 1438 }, { "start_pos": 1469, "end_pos": 1471 }, { "start_pos": 1498, "end_pos": 1500 }, { "start_pos": 1523, "end_pos": 1525 }, { "start_pos": 1651, "end_pos": 1653 }, { "start_pos": 1685, "end_pos": 1687 }, { "start_pos": 344, "end_pos": 346 }, { "start_pos": 456, "end_pos": 458 }, { "start_pos": 460, "end_pos": 462 }, { "start_pos": 820, "end_pos": 822 }, { "start_pos": 850, "end_pos": 852 }, { "start_pos": 857, "end_pos": 859 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", 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[], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YP71", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP71" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "REM1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP71", "locus": { "chromosome": "20", "start_pos": 10330747, "end_pos": 10325043, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013995", "url": "https://www.ensembl.org/id/ENSGALG00010013995" } ] } } ], "crossref": [ { "id": "A0A8V0YP71", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YP71", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd04148", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04148", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001806", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001806", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005225", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005225", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017358", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017358", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051641", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051641", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YME2", "url": "https://www.orthodb.org/?gene=A0A8V0YME2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YP71", "url": "https://www.orthodb.org/?gene=A0A8V0YP71", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45775", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45775", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45775:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45775:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00071", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00071", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YME2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YME2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YME2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YME2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YP71", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP71", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YP71-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP71-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "VAGRSFGRQLCCVVRSTLKAPSYRPPVPPDLRPAASPAPSGAAAKARPGLSVAVPQRCLSAGPDAPSCWEHRVVLLGDPGVGKTSLANAFAGIQERDLLEQHGEAAYERTLLVDGEETTLLVLDTWEPERRGEESWRRSQCLQVGNAYVIVYSITDRSSFESASELRIHLRRARQAEDIPIILVGNKSDLVRCREVSIEEGRACAVVFDCKFIETSAALQHNVDELFEGVVRQLRLRREGKESASSHRRKESLTKRARRFLDRMVARNSSKVALKARSKSCHDLSVL", "length": 287, "header": "tr|A0A8V0YP71-1|A0A8V0YP71_CHICK Isoform 1 of RRAD and GEM like GTPase 1 OS=Gallus gallus OX=9031 GN=REM1 PE=3 SV=1 CANONICAL=A0A8V0YP71-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YME2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP71/entry#A0A8V0YME2-1", "sequence": { "sequence": "MTLNTQPGSKSPLRRRASTPLPRVPGAAPRAQLGHPQLGQSSSEPAARAAAPRGSWSSESSASSSCWEHRVVLLGDPGVGKTSLANAFAGIQERDLLEQHGEAAYERTLLVDGEETTLLVLDTWEPERRGEESWRRSQCLQVGNAYVIVYSITDRSSFESASELRIHLRRARQAEDIPIILVGNKSDLVRCREVSIEEGRACAVVFDCKFIETSAALQHNVDELFEGVVRQLRLRREGKESASSHRRKESLTKRARRFLDRMVALKARSKSCHDLSVL", "length": 278, "header": "tr|A0A8V0YME2-1|A0A8V0YME2_CHICK Computationally mapped isoform of GTP-binding protein OS=Gallus gallus OX=9031 GN=REM1 PE=1 SV=1 CANONICAL=A0A8V0YP71-1" }, "locus": { "chromosome": "20", "start_pos": 10328295, "end_pos": 10326091, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033552.1", "url": "https://www.ensembl.org/id/ENSGALT00010033552.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019774.1", "url": "https://www.ensembl.org/id/ENSGALP00010019774.1" } ] } }, { "isoform_ac": "A0A8V0YP71-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP71/entry#A0A8V0YP71-1", "sequence": { "sequence": "VAGRSFGRQLCCVVRSTLKAPSYRPPVPPDLRPAASPAPSGAAAKARPGLSVAVPQRCLSAGPDAPSCWEHRVVLLGDPGVGKTSLANAFAGIQERDLLEQHGEAAYERTLLVDGEETTLLVLDTWEPERRGEESWRRSQCLQVGNAYVIVYSITDRSSFESASELRIHLRRARQAEDIPIILVGNKSDLVRCREVSIEEGRACAVVFDCKFIETSAALQHNVDELFEGVVRQLRLRREGKESASSHRRKESLTKRARRFLDRMVARNSSKVALKARSKSCHDLSVL", "length": 287, "header": "tr|A0A8V0YP71-1|A0A8V0YP71_CHICK Isoform 1 of RRAD and GEM like GTPase 1 OS=Gallus gallus OX=9031 GN=REM1 PE=3 SV=1 CANONICAL=A0A8V0YP71-1" }, "locus": { "chromosome": "20", "start_pos": 10328295, "end_pos": 10325092, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033555.1", "url": "https://www.ensembl.org/id/ENSGALT00010033555.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019776.1", "url": "https://www.ensembl.org/id/ENSGALP00010019776.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "GTPase activity", "id": "GO:0003924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003924", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YP71", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP71" } ], "pmid": "" }, { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YP71", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP71" } ], "pmid": "" }, { "name": "calcium channel regulator activity", "id": "GO:0005246", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005246", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YP71", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP71" } ], "pmid": "" }, { "name": "transmembrane transporter binding", "id": "GO:0044325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044325", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YP71", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP71" } ], "pmid": "" }, { "name": "calmodulin binding", "id": "GO:0005516", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005516", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YP71", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP71" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YP71", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP71" } ], "pmid": "" }, { "name": "I band", "id": "GO:0031674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031674", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YP71", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP71" } ], "pmid": "" }, { "name": "T-tubule", "id": "GO:0030315", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030315", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YP71", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP71" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 186, "end_pos": 188, "annotation": "n_glycosylation_sequon" }, { "start_pos": 268, "end_pos": 270, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 186, "end_pos": 188 }, { "start_pos": 268, "end_pos": 270 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YP80-1", "uniprot_ac": "A0A8V0YP80", "uniprot_id": "A0A8V0YP80_CHICK", "mass": { "chemical_mass": 46856.0, "monoisotopic_mass": 46856.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Core shell protein Gag P30 domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A8V0YP80", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP80/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YP80", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP80" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP80", "locus": {} } ], "crossref": [ { "id": "IPR003036", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003036", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008919", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008919", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036875", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036875", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050462", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050462", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR33166", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR33166", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02093", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02093", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YP80", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP80", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YP80-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP80-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGVLHDPFVLTLEKEWREKGENKVKHCCLSYSIGQQCIKTSKIRESEELLEHYQPPGETPTPPDGMQVPLRTQDGAQAPPEAQEPPEAQAPSEVQVSSGAQAPPDSPIASQTWSQQPLIIAPLREAVGPKGGPVLIKVPFSSFDLETWKSVSKDYWNDPLGVARHFQFLIRQHEPDWSDIQLLLDQVTETEKQLILKTAQTLDEDSIRGRNEDVKDHFPLQNPYWDPNTRAGRECLEMYREWVVKGMERAIPKTINWSNLFAVRQGLKESSSEFLDKLRDAMRKRTSLNPGSEEGIQQLVSLFIGQSVGDIRRKLQKLKAPAAQNLESLLEEAWRVFSNRHEVEKRREKKMLIAVLQETKRSEQNKAQKPLQKDQCAICRKRGHWKNECPLRKQKGKGGAWAKVQAPVEED", "length": 411, "header": "tr|A0A8V0YP80-1|A0A8V0YP80_CHICK Isoform 1 of Core shell protein Gag P30 domain-containing protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0YP80-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YP80-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP80/entry#A0A8V0YP80-1", "sequence": { "sequence": "MGVLHDPFVLTLEKEWREKGENKVKHCCLSYSIGQQCIKTSKIRESEELLEHYQPPGETPTPPDGMQVPLRTQDGAQAPPEAQEPPEAQAPSEVQVSSGAQAPPDSPIASQTWSQQPLIIAPLREAVGPKGGPVLIKVPFSSFDLETWKSVSKDYWNDPLGVARHFQFLIRQHEPDWSDIQLLLDQVTETEKQLILKTAQTLDEDSIRGRNEDVKDHFPLQNPYWDPNTRAGRECLEMYREWVVKGMERAIPKTINWSNLFAVRQGLKESSSEFLDKLRDAMRKRTSLNPGSEEGIQQLVSLFIGQSVGDIRRKLQKLKAPAAQNLESLLEEAWRVFSNRHEVEKRREKKMLIAVLQETKRSEQNKAQKPLQKDQCAICRKRGHWKNECPLRKQKGKGGAWAKVQAPVEED", "length": 411, "header": "tr|A0A8V0YP80-1|A0A8V0YP80_CHICK Isoform 1 of Core shell protein Gag P30 domain-containing protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0YP80-1" }, "locus": { "chromosome": "W", "start_pos": 6868037, "end_pos": 6866805, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030911.1", "url": "https://www.ensembl.org/id/ENSGALT00010030911.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017950.1", "url": "https://www.ensembl.org/id/ENSGALP00010017950.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 61, "start_aa": "Thr", "end_pos": 61, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr61", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YP80", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP80" } ], "pmid": "" }, { "name": "nucleic acid binding", "id": "GO:0003676", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003676", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YP80", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP80" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "virion assembly", "id": "GO:0019068", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019068", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YP80", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP80" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 256, "end_pos": 258, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YP80", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP80" }, { "id": "PF02093", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02093" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Core shell protein Gag P30", "eco_id": "ECO_0000259", "start_pos": 144, "end_pos": 338, "start_aa": "Asp", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 61 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 256, "end_pos": 258 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YPA2-1", "uniprot_ac": "A0A8V0YPA2", "uniprot_id": "A0A8V0YPA2_CHICK", "mass": { "chemical_mass": 50231.0, "monoisotopic_mass": 50231.0 }, "refseq": {}, "gene_names": [ { "name": "SEPTIN6", "type": "recommended", "evidence": [ { "id": "A0A8V0YPA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPA2" } ] } ], "protein_names": [ { "name": "Septin", "type": "recommended", "evidence": [ { "id": "A0A8V0YPA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPA2/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPA2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPA2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SEPTIN6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPA2", "locus": { "chromosome": "4", "start_pos": 16489598, "end_pos": 16464208, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010016398", "url": "https://www.ensembl.org/id/ENSGALG00010016398" } ] } } ], "crossref": [ { "id": "A0A8V0YPA2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YPA2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000008633", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000008633", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd01850", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01850", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "422369", "url": "https://www.ncbi.nlm.nih.gov/gene/422369", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR016491", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016491", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR030379", "url": "https://www.ebi.ac.uk/interpro/entry/IPR030379", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A1L1RNQ9", "url": "https://www.orthodb.org/?gene=A0A1L1RNQ9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YP91", "url": "https://www.orthodb.org/?gene=A0A8V0YP91", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YPA2", "url": "https://www.orthodb.org/?gene=A0A8V0YPA2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YW19", "url": "https://www.orthodb.org/?gene=A0A8V0YW19", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YXL6", "url": "https://www.orthodb.org/?gene=A0A8V0YXL6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR18884", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR18884", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00735", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00735", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A1L1RNQ9", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RNQ9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1L1RNQ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RNQ9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YP91", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP91", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YP91-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP91-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YPA2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPA2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YPA2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPA2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YW19", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YW19", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YW19-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YW19-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YXL6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXL6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YXL6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXL6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAAEVARQGEGCRTVPLSGHVGFDSLPDQLVNKSVNHGFCFNILCVGETGLGKSTLMDTLFNTKFEGDPASHSQPGVQLKSSTYDLQESNVNLKLTIVSTVGFGDQINKEDSYKPIVEFIDAQFEAYLQEELKIKRVLHNYHDTRIHACLYFIAPTGHSLKSLDLVTMKKLDSKVNIIPIIAKSDAISKSELTKFKIKITSELVSNGVQIYQFPTDDESVAEINGTMNAHLPFAVIGSTEELKIGNKMMKARQYPWGTVQVENEAHCDFVKLREMLIRVNMEDLREQTHTRHYELYRRCKLEEMGFKDTDPDSKPFSLQETYEAKRNEFLGELQKKEEAMRQMFVQRVKEKEAELKEAEKELHEKFDRLKKLHQDEKKKLEDHKLLKEIRKGKIRVSCRAFPFAPEVNAPHIQLTRSHAILPVSSPLLIAPLLRSPVCSK", "length": 441, "header": "tr|A0A8V0YPA2-1|A0A8V0YPA2_CHICK Isoform 1 of Septin OS=Gallus gallus OX=9031 GN=SEPTIN6 PE=1 SV=1 CANONICAL=A0A8V0YPA2-1" }, "isoforms": [ { "isoform_ac": "A0A1L1RNQ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPA2/entry#A0A1L1RNQ9-1", "sequence": { "sequence": "MEGEGCRTVPLSGHVGFDSLPDQLVNKSVNHGFCFNILCVGETGLGKSTLMDTLFNTKFEGDPASHSQPGVQLKSSTYDLQESNVNLKLTIVSTVGFGDQINKEDSYKPIVEFIDAQFEAYLQEELKIKRVLHNYHDTRIHACLYFIAPTGHSLKSLDLVTMKKLDSKVNIIPIIAKSDAISKSELTKFKIKITSELVSNGVQIYQFPTDDESVAEINGTMNAHLPFAVIGSTEELKIGNKMMKARQYPWGTVQVENEAHCDFVKLREMLIRVNMEDLREQTHTRHYELYRRCKLEEMGFKDTDPDSKPFSLQETYEAKRNEFLGELQKKEEAMRQMFVQRVKEKEAELKEAEKELHEKFDRLKKLHQDEKKKLEDKKKSLDDEVNAFKQRKTAAELLQSQAQQAGGSQTLKRDKERKN", "length": 419, "header": "tr|A0A1L1RNQ9-1|A0A1L1RNQ9_CHICK Computationally mapped isoform of Septin OS=Gallus gallus OX=9031 GN=SEPTIN6 PE=1 SV=2 CANONICAL=A0A8V0YPA2-1" }, "locus": { "chromosome": "4", "start_pos": 16484210, "end_pos": 16467372, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010039521.1", "url": "https://www.ensembl.org/id/ENSGALT00010039521.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010022808.1", "url": "https://www.ensembl.org/id/ENSGALP00010022808.1" } ] } }, { "isoform_ac": "A0A8V0YP91-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPA2/entry#A0A8V0YP91-1", "sequence": { "sequence": "MAAAEVARQGEGCRTVPLSGHVGFDSLPDQLVNKSVNHGFCFNILCVGETGLGKSTLMDTLFNTKFEGDPASHSQPGVQLKSSTYDLQESNVNLKLTIVSTVGFGDQINKEDSYKPIVEFIDAQFEAYLQEELKIKRVLHNYHDTRIHACLYFIAPTGHSLKSLDLVTMKKLDSKVNIIPIIAKSDAISKSELTKFKIKITSELVSNGVQIYQFPTDDESVAEINGTMNAHLPFAVIGSTEELKIGNKMMKARQYPWGTVQVENEAHCDFVKLREMLIRVNMEDLREQTHTRHYELYRRCKLEEMGFKDTDPDSKPFSLQETYEAKRNEFLGELQKKEEAMRQMFVQRVKEKEAELKEAEKELHEKFDRLKKLHQDEKKKLEDKKKSLDDEVNAFKQRKTAAELLQSQAQQAGGSQTLKRDKERKNSGFL", "length": 430, "header": "tr|A0A8V0YP91-1|A0A8V0YPA2_CHICK Computationally mapped isoform of Septin OS=Gallus gallus OX=9031 GN=SEPTIN6 PE=1 SV=1 CANONICAL=A0A8V0YPA2-1" }, "locus": { "chromosome": "4", "start_pos": 16486623, "end_pos": 16464221, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010039531.1", "url": "https://www.ensembl.org/id/ENSGALT00010039531.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010022815.1", "url": "https://www.ensembl.org/id/ENSGALP00010022815.1" } ] } }, { "isoform_ac": "A0A8V0YPA2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPA2/entry#A0A8V0YPA2-1", "sequence": { "sequence": "MAAAEVARQGEGCRTVPLSGHVGFDSLPDQLVNKSVNHGFCFNILCVGETGLGKSTLMDTLFNTKFEGDPASHSQPGVQLKSSTYDLQESNVNLKLTIVSTVGFGDQINKEDSYKPIVEFIDAQFEAYLQEELKIKRVLHNYHDTRIHACLYFIAPTGHSLKSLDLVTMKKLDSKVNIIPIIAKSDAISKSELTKFKIKITSELVSNGVQIYQFPTDDESVAEINGTMNAHLPFAVIGSTEELKIGNKMMKARQYPWGTVQVENEAHCDFVKLREMLIRVNMEDLREQTHTRHYELYRRCKLEEMGFKDTDPDSKPFSLQETYEAKRNEFLGELQKKEEAMRQMFVQRVKEKEAELKEAEKELHEKFDRLKKLHQDEKKKLEDHKLLKEIRKGKIRVSCRAFPFAPEVNAPHIQLTRSHAILPVSSPLLIAPLLRSPVCSK", "length": 441, "header": "tr|A0A8V0YPA2-1|A0A8V0YPA2_CHICK Isoform 1 of Septin OS=Gallus gallus OX=9031 GN=SEPTIN6 PE=1 SV=1 CANONICAL=A0A8V0YPA2-1" }, "locus": { "chromosome": "4", "start_pos": 16486750, "end_pos": 16464221, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010039543.1", "url": "https://www.ensembl.org/id/ENSGALT00010039543.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010022825.1", "url": "https://www.ensembl.org/id/ENSGALP00010022825.1" } ] } }, { "isoform_ac": "A0A8V0YW19-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPA2/entry#A0A8V0YW19-1", "sequence": { "sequence": "MGFVSTSCVTGLGKSTLMDTLFNTKFEGDPASHSQPGVQLKSSTYDLQESNVNLKLTIVSTVGFGDQINKEDSYKPIVEFIDAQFEAYLQEELKIKRVLHNYHDTRIHACLYFIAPTGHSLKSLDLVTMKKLDSKVNIIPIIAKSDAISKSELTKFKIKITSELVSNGVQIYQFPTDDESVAEINGTMNAHLPFAVIGSTEELKIGNKMMKARQYPWGTVQVENEAHCDFVKLREMLIRVNMEDLREQTHTRHYELYRRCKLEEMGFKDTDPDSKPFSLQETYEAKRNEFLGELQKKEEAMRQMFVQRVKEKEAELKEAEKELHEKFDRLKKLHQDEKKKLEDKKKSLDDEVNAFKQRKTAAELLQSQAQQAGGSQTLKRDKERKNSGFL", "length": 390, "header": "tr|A0A8V0YW19-1|A0A8V0YW19_CHICK Computationally mapped isoform of Septin OS=Gallus gallus OX=9031 GN=SEPTIN6 PE=1 SV=1 CANONICAL=A0A8V0YPA2-1" }, "locus": { "chromosome": "4", "start_pos": 16486623, "end_pos": 16467923, "strand": "-", "evidence": [ { "database": 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"MIEQQKRKAPGGPVPGPVPGPAPGPGAGSAPGAAPGPTPGPDLPLVPSAAKRPRHDPPAAGGGGGQPSTGALLQSGPPRCSSLQAPIMLLSGHEGEVYCCKFHPGGNTLASAGFDRLILLWNVYGDCDNYATLKGHSGAVMELHYNTDGSMLFSASTDKTVAVWDSETGERVKRLKGHTSFVNSCYPARRGPQLVCTGSDDGTVKLWDIRKKAAVQTFQNTYQVLAVTFNDTSDQIISGGIDNDIKVWDLRQNKLTYTMRGHADSVTGLSLSSEGSYLLSNAMDNTVRIWDVRPFAPKERCVKIFQGNVHNFEKNLLRCSWSPDGSKIAGGSADRFVYVWDTTSRRILYKLPGHAGSVNELAFHPEEPISKYSPNQVIWGNRFRAGCMLVFHKTAQILLVAQTPSIKELGERSPLQPGAKPWAEQWGSTCGPG", "length": 433, "header": "tr|A0A8V0YPF8-1|A0A8V0YPF8_CHICK Isoform 1 of U5 small nuclear ribonucleoprotein 40 kDa protein OS=Gallus gallus OX=9031 GN=SNRNP40 PE=1 SV=1 CANONICAL=A0A8V0YPF8-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YB78-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPF8/entry#A0A8V0YB78-1", "sequence": { "sequence": "MIEQQKRKAPGGPVPGPVPGPAPGPGAGSAPGAAPGPTPGPDLPLVPSAAKRPRHDPPAAGGGGGQPSTGALLQSGPPRCSSLQAPIMLLSGHEGEVYCCKFHPGGNTLASAGFDRLILLWNVYGDCDNYATLKGHSGAVMELHYNTDGSMLFSASTDKTVAVWDSETGERVKRLKGHTSFVNSCYPARRGPQLVCTGSDDGTVKLWDIRKKAAVQTFQNTYQVLAVTFNDTSDQIISGGIDNDIKVWDLRQNKLTYTMRGHADSVTGLSLSSEGSYLLSNAMDNTVRIWDVRPFAPKERCVKIFQGNVHNFEKNLLRCSWSPDGSKIAGGSADRFVYVWDTTSRRILYKLPGHAGSVNELAFHPEEPINQRLCWKSRAISPL", "length": 383, "header": "tr|A0A8V0YB78-1|A0A8V0YB78_CHICK Computationally mapped isoform of U5 small nuclear ribonucleoprotein 40 kDa protein OS=Gallus gallus OX=9031 GN=SNRNP40 PE=1 SV=1 CANONICAL=A0A8V0YPF8-1" }, "locus": { "chromosome": "23", "start_pos": 952631, "end_pos": 943187, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031016.1", "url": "https://www.ensembl.org/id/ENSGALT00010031016.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018027.1", "url": "https://www.ensembl.org/id/ENSGALP00010018027.1" } ] } }, { "isoform_ac": "A0A8V0YPF8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPF8/entry#A0A8V0YPF8-1", "sequence": { "sequence": "MIEQQKRKAPGGPVPGPVPGPAPGPGAGSAPGAAPGPTPGPDLPLVPSAAKRPRHDPPAAGGGGGQPSTGALLQSGPPRCSSLQAPIMLLSGHEGEVYCCKFHPGGNTLASAGFDRLILLWNVYGDCDNYATLKGHSGAVMELHYNTDGSMLFSASTDKTVAVWDSETGERVKRLKGHTSFVNSCYPARRGPQLVCTGSDDGTVKLWDIRKKAAVQTFQNTYQVLAVTFNDTSDQIISGGIDNDIKVWDLRQNKLTYTMRGHADSVTGLSLSSEGSYLLSNAMDNTVRIWDVRPFAPKERCVKIFQGNVHNFEKNLLRCSWSPDGSKIAGGSADRFVYVWDTTSRRILYKLPGHAGSVNELAFHPEEPISKYSPNQVIWGNRFRAGCMLVFHKTAQILLVAQTPSIKELGERSPLQPGAKPWAEQWGSTCGPG", "length": 433, "header": "tr|A0A8V0YPF8-1|A0A8V0YPF8_CHICK Isoform 1 of U5 small nuclear ribonucleoprotein 40 kDa protein OS=Gallus gallus OX=9031 GN=SNRNP40 PE=1 SV=1 CANONICAL=A0A8V0YPF8-1" }, "locus": { "chromosome": "23", "start_pos": 952631, "end_pos": 943846, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031023.1", "url": "https://www.ensembl.org/id/ENSGALT00010031023.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018033.1", "url": "https://www.ensembl.org/id/ENSGALP00010018033.1" } ] } }, { "isoform_ac": "A0A8V0YPG3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPF8/entry#A0A8V0YPG3-1", "sequence": { "sequence": "MIEQQKRKAPGGPVPGPVPGPAPGPGAGSAPGAAPGPTPGPDLPLVPSAAKRPRHDPPAAGGGGGQPSTGALLQSGPPRCSSLQAPIMLLSGHEGEVYCCKFHPGGNTLASAGFDRLILLWNVYGDCDNYATLKGHSGAVMELHYNTDGSMLFSASTDKTVAVWDSETGERVKRLKGHTSFVNSCYPARRGPQLVCTGSDDGTVKLWDIRKKAAVQTFQNTYQVLAVTFNDTSDQIISGGIDNDIKVWDLRQNKLTYTMRGHADSVTGLSLSSEGSYLLSNAMDNTVRIWDVRPFAPKERCVKIFQGNVHNFEKNLLRCSWSPDGSKIAGGSADRFVYVWDTTSRRILYKLPGHAGSVNELAFHPEEPIILSASSDKRLYMGEIQ", "length": 385, "header": "tr|A0A8V0YPG3-1|A0A8V0YPG3_CHICK Computationally mapped isoform of U5 small nuclear ribonucleoprotein 40 kDa protein OS=Gallus gallus OX=9031 GN=SNRNP40 PE=1 SV=1 CANONICAL=A0A8V0YPF8-1" }, "locus": { "chromosome": "23", "start_pos": 952631, "end_pos": 942313, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031032.1", "url": "https://www.ensembl.org/id/ENSGALT00010031032.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018038.1", "url": "https://www.ensembl.org/id/ENSGALP00010018038.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 38, "start_aa": "Thr", "end_pos": 38, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr38", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "R-GGA-72163", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-72163", "resource": "Reactome", "description": "mRNA Splicing - Major Pathway" }, { "id": "R-GGA-72165", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-72165", "resource": "Reactome", "description": "mRNA Splicing - Minor Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "RNA splicing, via transesterification reactions", "id": "GO:0000375", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000375", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPF8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPF8" } ], "pmid": "" }, { "name": "mRNA processing", "id": "GO:0006397", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006397", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPF8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPF8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "nuclear speck", "id": "GO:0016607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016607", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPF8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPF8" } ], "pmid": "" }, { "name": "catalytic step 2 spliceosome", "id": "GO:0071013", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071013", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPF8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPF8" } ], "pmid": "" }, { "name": "U2-type catalytic step 2 spliceosome", "id": "GO:0071007", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071007", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPF8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPF8" } ], "pmid": "" }, { "name": "U5 snRNP", "id": "GO:0005682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005682", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPF8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPF8" } ], "pmid": "" }, { "name": "spliceosomal complex", "id": "GO:0005681", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005681", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPF8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPF8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 230, "end_pos": 232, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YPF8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPF8" }, { "id": "PF23098", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23098" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Nucleolar protein 10-like N-terminal", "eco_id": "ECO_0000259", "start_pos": 142, "end_pos": 292, "start_aa": "Glu", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 38 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 230, "end_pos": 232 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YPG2-1", "uniprot_ac": "A0A8V0YPG2", "uniprot_id": "A0A8V0YPG2_CHICK", "mass": { "chemical_mass": 57057.0, "monoisotopic_mass": 57057.0 }, "refseq": { "ac": "XP_420218", "name": "interleukin-13 receptor subunit alpha-1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_420218" }, "gene_names": [ { "name": "IL13RA1", "type": "recommended", "evidence": [ { "id": "A0A8V0YPG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPG2" } ] }, { "name": "IL13RA1", "type": "synonym", "evidence": [ { "id": "XP_420218", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_420218" } ] } ], "protein_names": [ { "name": "Interleukin 13 receptor subunit alpha 1", "type": "synonym", "evidence": [ { "id": "A0A8V0YPG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPG2/entry#names_and_taxonomy" } ] }, { "name": "interleukin-13 receptor subunit alpha-1", "type": "synonym", "evidence": [ { "id": "XP_420218", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_420218" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052535.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_420218.3. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_420218", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_420218" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPG2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPG2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "IL13RA1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPG2", "locus": { "chromosome": "4", "start_pos": 3362081, "end_pos": 3348078, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010014682", "url": "https://www.ensembl.org/id/ENSGALG00010014682" } ] } } ], "crossref": [ { "id": "A0A8V0YPG2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YPG2", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00063", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00063", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "422230", "url": "https://www.ncbi.nlm.nih.gov/gene/422230", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003532", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003532", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003961", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003961", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015321", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015321", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036116", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036116", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040566", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040566", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048648", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048648", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:422230", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422230", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "RPVCASK", "url": "https://omabrowser.org/oma/group/RPVCASK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YPG2", "url": "https://www.orthodb.org/?gene=A0A8V0YPG2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23037", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23037", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23037:SF46", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23037:SF46", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF09240", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09240", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF18001", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18001", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21605", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21605", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_420218", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_420218", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YPG2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPG2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YPG2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPG2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPGEDPWEAQQSCGANTLLRSAAAGGSGTSGQQARREAAQVGPGWPPPPTEAAPPRLGLPGRAAERLFPSGPAPATGSGSVRPRSDGRSGGDMESGGSFGAPLRCRLLFLAACWAVAATAAGEKVLPPPSNLSYSFIQICTLNWTWNPPENISSSCDLEYSSDILIDEVSQHKNEWRKSLFRVTDTVLNKEMRFKVRSECKNSNATNHSQWVETSVPPKGVPGTAAVGLSCVWHNLEYMFCMWHPGENASSDTNYTLFYWFDGLERHRECENYSVSQGSFECAFNFTFPQAANRYPPISILIRGDSENVMPVCATENPTTLVKPATPTIVKLLYVNNGIHLQWSESGTIPANCLSYEVRYHNGDSTTAQIIQVKYNSTSIPSVDRNSKYTFQVRAQPKVECYSSKFYSEWSEEKSIGENPNSAFNFLLIVTIPLIVTVSTIILLVYLKRLKILILPPIPDPREILKRMFGEQNEDPQSCAKEDCMNGYDGLIKEEEIHSLILIETPESSNSEKEHR", "length": 516, "header": "tr|A0A8V0YPG2-1|A0A8V0YPG2_CHICK Isoform 1 of Interleukin 13 receptor subunit alpha 1 OS=Gallus gallus OX=9031 GN=IL13RA1 PE=3 SV=1 CANONICAL=A0A8V0YPG2-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YPG2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPG2/entry#A0A8V0YPG2-1", "sequence": { "sequence": "MPGEDPWEAQQSCGANTLLRSAAAGGSGTSGQQARREAAQVGPGWPPPPTEAAPPRLGLPGRAAERLFPSGPAPATGSGSVRPRSDGRSGGDMESGGSFGAPLRCRLLFLAACWAVAATAAGEKVLPPPSNLSYSFIQICTLNWTWNPPENISSSCDLEYSSDILIDEVSQHKNEWRKSLFRVTDTVLNKEMRFKVRSECKNSNATNHSQWVETSVPPKGVPGTAAVGLSCVWHNLEYMFCMWHPGENASSDTNYTLFYWFDGLERHRECENYSVSQGSFECAFNFTFPQAANRYPPISILIRGDSENVMPVCATENPTTLVKPATPTIVKLLYVNNGIHLQWSESGTIPANCLSYEVRYHNGDSTTAQIIQVKYNSTSIPSVDRNSKYTFQVRAQPKVECYSSKFYSEWSEEKSIGENPNSAFNFLLIVTIPLIVTVSTIILLVYLKRLKILILPPIPDPREILKRMFGEQNEDPQSCAKEDCMNGYDGLIKEEEIHSLILIETPESSNSEKEHR", "length": 516, "header": "tr|A0A8V0YPG2-1|A0A8V0YPG2_CHICK Isoform 1 of Interleukin 13 receptor subunit alpha 1 OS=Gallus gallus OX=9031 GN=IL13RA1 PE=3 SV=1 CANONICAL=A0A8V0YPG2-1" }, "locus": { "chromosome": "4", "start_pos": 3359447, "end_pos": 3348277, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010035239.1", "url": "https://www.ensembl.org/id/ENSGALT00010035239.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020535.1", "url": "https://www.ensembl.org/id/ENSGALP00010020535.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 50, "start_aa": "Thr", "end_pos": 50, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr50", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:422230", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422230", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "F1RU78-1", "protein_name": "Interleukin-13 receptor subunit alpha-1", "gene_name": "IL13RA1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MERPARLYGLWALLFCAGGGGLAAPAETQPPVTNLSVSVENLCTVTWTWNPPEGASPNCSLWYLSHFGNKQDKKITPETHRSEEVPLNERICLQVGSQCSTNESEKPSILVEKCISPPEGDPESAVTELQCVWHNLRYMKCTWLPGRNTSPDTNYTLYYWHSSLGQILQCENIYREDQHIACSFALTKVKDSNFDSSVQIMVKDNAGKIRPAFSIVPSSSHVKPDPPHIKSLSFQNGDLYVQWKNPQNFYSRCLSYQVEVNNTQAKTHDIFYVEEAKCQNSEFEGNLEGMICFMVPGVLPDTLNTVRIRVKTNKLCYEDDKLWSNWSQAMSIGQKANPTFYITTLLIIPVIVAAAIIVLLLYLKRLKIIIFPPIPDPGKIFKEMFGDQNDDTLHWKKYDIYEKQTKEETDSVVLIESLKRAAQ", "length": 423 }, "evidence": [ { "id": "A0A8V0YPG2", "url": "https://omabrowser.org/oma/group/A0A8V0YPG2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "O09030-1", "protein_name": "Interleukin-13 receptor subunit alpha-1", "gene_name": "Il13ra1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MARPALLGELLVLLLWTATVGQVAAATEVQPPVTNLSVSVENLCTIIWTWSPPEGASPNCTLRYFSHFDDQQDKKIAPETHRKEELPLDEKICLQVGSQCSANESEKPSPLVKKCISPPEGDPESAVTELKCIWHNLSYMKCSWLPGRNTSPDTHYTLYYWYSSLEKSRQCENIYREGQHIACSFKLTKVEPSFEHQNVQIMVKDNAGKIRPSCKIVSLTSYVKPDPPHIKHLLLKNGALLVQWKNPQNFRSRCLTYEVEVNNTQTDRHNILEVEEDKCQNSESDRNMEGTSCFQLPGVLADAVYTVRVRVKTNKLCFDDNKLWSDWSEAQSIGKEQNSTFYTTMLLTIPVFVAVAVIILLFYLKRLKIIIFPPIPDPGKIFKEMFGDQNDDTLHWKKYDIYEKQSKEETDSVVLIENLKKAAP", "length": 424 }, "evidence": [ { "id": "A0A8V0YPG2", "url": "https://omabrowser.org/oma/group/A0A8V0YPG2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P78552-1", "protein_name": "Interleukin-13 receptor subunit alpha-1", "gene_name": "IL13RA1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEWPARLCGLWALLLCAGGGGGGGGAAPTETQPPVTNLSVSVENLCTVIWTWNPPEGASSNCSLWYFSHFGDKQDKKIAPETRRSIEVPLNERICLQVGSQCSTNESEKPSILVEKCISPPEGDPESAVTELQCIWHNLSYMKCSWLPGRNTSPDTNYTLYYWHRSLEKIHQCENIFREGQYFGCSFDLTKVKDSSFEQHSVQIMVKDNAGKIKPSFNIVPLTSRVKPDPPHIKNLSFHNDDLYVQWENPQNFISRCLFYEVEVNNSQTETHNVFYVQEAKCENPEFERNVENTSCFMVPGVLPDTLNTVRIRVKTNKLCYEDDKLWSNWSQEMSIGKKRNSTLYITMLLIVPVIVAGAIIVLLLYLKRLKIIIFPPIPDPGKIFKEMFGDQNDDTLHWKKYDIYEKQTKEETDSVVLIENLKKASQ", "length": 427 }, "evidence": [ { "id": "A0A8V0YPG2", "url": "https://omabrowser.org/oma/group/A0A8V0YPG2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "external side of plasma membrane", "id": "GO:0009897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009897", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPG2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPG2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "cytokine-mediated signaling pathway", "id": "GO:0019221", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019221", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPG2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPG2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "cytokine receptor activity", "id": "GO:0004896", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004896", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPG2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPG2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 131, "end_pos": 133, "annotation": "n_glycosylation_sequon" }, { "start_pos": 143, "end_pos": 145, "annotation": "n_glycosylation_sequon" }, { "start_pos": 151, "end_pos": 153, "annotation": "n_glycosylation_sequon" }, { "start_pos": 204, "end_pos": 206, "annotation": "n_glycosylation_sequon" }, { "start_pos": 207, "end_pos": 209, "annotation": "n_glycosylation_sequon" }, { "start_pos": 248, "end_pos": 250, "annotation": "n_glycosylation_sequon" }, { "start_pos": 254, "end_pos": 256, "annotation": "n_glycosylation_sequon" }, { "start_pos": 272, "end_pos": 274, "annotation": "n_glycosylation_sequon" }, { "start_pos": 285, "end_pos": 287, "annotation": "n_glycosylation_sequon" }, { "start_pos": 376, "end_pos": 378, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YPG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPG2" }, { "id": "PS50853", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50853" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Fibronectin type-III", "eco_id": "ECO_0000259", "start_pos": 323, "end_pos": 421, "start_aa": "Lys", "end_aa": "Asn", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 50 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 131, "end_pos": 133 }, { "start_pos": 143, "end_pos": 145 }, { "start_pos": 151, "end_pos": 153 }, { "start_pos": 204, "end_pos": 206 }, { "start_pos": 207, "end_pos": 209 }, { "start_pos": 248, "end_pos": 250 }, { "start_pos": 254, "end_pos": 256 }, { "start_pos": 272, "end_pos": 274 }, { "start_pos": 285, "end_pos": 287 }, { "start_pos": 376, "end_pos": 378 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": 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"sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YPI2-1", "uniprot_ac": "A0A8V0YPI2", "uniprot_id": "A0A8V0YPI2_CHICK", "mass": { "chemical_mass": 60802.0, "monoisotopic_mass": 60802.0 }, "refseq": { "ac": "XP_015141520", "name": "spermine oxidase isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015141520" }, "gene_names": [ { "name": "SMOX", "type": "recommended", "evidence": [ { "id": "A0A8V0YPI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPI2" } ] }, { "name": "SMOX", "type": "synonym", "evidence": [ { "id": "XP_015141520", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015141520" } ] } ], "protein_names": [ { "name": "Peroxisomal N(1)-acetyl-spermine/spermidine oxidase", "type": "recommended", "evidence": [ { "id": "A0A8V0YPI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPI2/entry#names_and_taxonomy" } ] }, { "name": "1.5.3.13", "type": "synonym", "evidence": [ { "id": "A0A8V0YPI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPI2/entry#names_and_taxonomy" } ] }, { "name": "Polyamine oxidase", "type": "synonym", "evidence": [ { "id": "A0A8V0YPI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPI2/entry#names_and_taxonomy" } ] }, { "name": "spermine oxidase isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015141520", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015141520" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052535.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015141520", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015141520" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPI2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPI2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SMOX", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPI2", "locus": { "chromosome": "4", "start_pos": 87973260, "end_pos": 88037452, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010016457", "url": "https://www.ensembl.org/id/ENSGALG00010016457" } ] } } ], "crossref": [ { "id": "A0A8V0YPI2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YPI2", "database": "AlphaFoldDB", "categories": [] }, { "id": "422934", "url": "https://www.ncbi.nlm.nih.gov/gene/422934", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002937", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002937", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036188", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036188", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050281", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050281", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:422934", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422934", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CITGCHS", "url": "https://omabrowser.org/oma/group/CITGCHS/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YPH7", "url": "https://www.orthodb.org/?gene=A0A8V0YPH7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YPI2", "url": "https://www.orthodb.org/?gene=A0A8V0YPI2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YVX1", "url": "https://www.orthodb.org/?gene=A0A8V0YVX1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10742", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10742", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10742:SF416", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10742:SF416", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01593", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01593", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-141334", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-141334", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-351200", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-351200", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_015141520", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015141520", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "25800", "url": "https://www.rhea-db.org/rhea/25800", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "25812", "url": "https://www.rhea-db.org/rhea/25812", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "25868", "url": "https://www.rhea-db.org/rhea/25868", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YPH7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPH7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YPH7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPH7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YPI2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPI2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YPI2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPI2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YVX1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YVX1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YVX1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YVX1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQSCEISGDSTDDPLSSGLRRTRQPRIVVIGAGLAGLSAAKALLESGFTDVTILEATDRIGGRVQSVKLGHATFELGATWIHGSHGNPVYHLAEDNGLLEETTDGERSVGRISLYSKNGVAYHLTNNGQRIPKDVVEEFSDLYNEVYNLTQEFFQRGKPVNAESQNSVGVFTRDVVRKRVKADPDDTEAVKRLKLAMIQQYLKVESCESSSHSMDEVSLSEFGEWTEIPGAHHIIPCGFIKIVEILARSIPESVIQLRKPVKCIHWNQSVSKEIERVADHNSDLPEEDRGSNVFVECEDCEFIPADHVIVTVSLGVLKKRHESLFHPRLPEEKVMAIEKLGINTTDKIFLEFEEPFWSSECNSIQFVWEDEAESESLTYPEELWYKKICSFDVLYPPERYGHVLSGWICGEEALIMEKCDDETVAETCTEMLRKFTGQPCPGSLGNPNIPKPRRILRSSWGSNPNFRGSYSYTQVGSSGADVEKLAKPLPYAESSKTTPMQVMFSGEATHRKYYSTTHGAVLSGQREAAHLIEMYQDLLQCRS", "length": 543, "header": "tr|A0A8V0YPI2-1|A0A8V0YPI2_CHICK Isoform 1 of Peroxisomal N(1)-acetyl-spermine/spermidine oxidase OS=Gallus gallus OX=9031 GN=SMOX PE=3 SV=1 CANONICAL=A0A8V0YPI2-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YPH7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPI2/entry#A0A8V0YPH7-1", "sequence": { "sequence": "MQSCEISGDSTDDPLSSGLRRTRQPRIVVIGAGLAGLSAAKALLESGFTDVTILEATDRIGGRVQSVKLGHATFELGATWIHGSHGNPVYHLAEDNGLLEETTDGERSVGRISLYSKNGVAYHLTNNGQRIPKDVVEEFSDLYNEVYNLTQEFFQRGKPVNAESQNSVGVFTRDVVRKRVKADPDDTEAVKRLKLAMIQQYLKVESCESSSHSMDEVSLSEFGEWTEIPGAHHIIPCGFIKIVEILARSIPESVIQLRKPVKCIHWNQSVSKEIERVADHNSDLPEEDRGSNVFVECEDCEFIPADHVIVTVSLGVLKKRHESLFHPRLPEEKVMAIEKLGINTTDKIFLEFEEPFWSSECNSIQFVWEDEAESESLTYPEELWYKKICSFDVLYPPERYGHVLSGWICGEEALIMEKCDDETVAETCTEMLRKFTGNPNIPKPRRILRSSWGSNPNFRGSYSYTQVGSSGADVEKLAKPLPYAESSKTTLRAMPMIHSHEELLPGIRMHSGK", "length": 513, "header": "tr|A0A8V0YPH7-1|A0A8V0YPI2_CHICK Computationally mapped isoform of Peroxisomal N(1)-acetyl-spermine/spermidine oxidase OS=Gallus gallus OX=9031 GN=SMOX PE=3 SV=1 CANONICAL=A0A8V0YPI2-1" }, "locus": { "chromosome": "4", "start_pos": 88013706, "end_pos": 87973315, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010039637.1", "url": "https://www.ensembl.org/id/ENSGALT00010039637.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010022896.1", "url": "https://www.ensembl.org/id/ENSGALP00010022896.1" } ] } }, { "isoform_ac": "A0A8V0YPI2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPI2/entry#A0A8V0YPI2-1", "sequence": { "sequence": "MQSCEISGDSTDDPLSSGLRRTRQPRIVVIGAGLAGLSAAKALLESGFTDVTILEATDRIGGRVQSVKLGHATFELGATWIHGSHGNPVYHLAEDNGLLEETTDGERSVGRISLYSKNGVAYHLTNNGQRIPKDVVEEFSDLYNEVYNLTQEFFQRGKPVNAESQNSVGVFTRDVVRKRVKADPDDTEAVKRLKLAMIQQYLKVESCESSSHSMDEVSLSEFGEWTEIPGAHHIIPCGFIKIVEILARSIPESVIQLRKPVKCIHWNQSVSKEIERVADHNSDLPEEDRGSNVFVECEDCEFIPADHVIVTVSLGVLKKRHESLFHPRLPEEKVMAIEKLGINTTDKIFLEFEEPFWSSECNSIQFVWEDEAESESLTYPEELWYKKICSFDVLYPPERYGHVLSGWICGEEALIMEKCDDETVAETCTEMLRKFTGQPCPGSLGNPNIPKPRRILRSSWGSNPNFRGSYSYTQVGSSGADVEKLAKPLPYAESSKTTPMQVMFSGEATHRKYYSTTHGAVLSGQREAAHLIEMYQDLLQCRS", "length": 543, "header": "tr|A0A8V0YPI2-1|A0A8V0YPI2_CHICK Isoform 1 of Peroxisomal N(1)-acetyl-spermine/spermidine oxidase OS=Gallus gallus OX=9031 GN=SMOX PE=3 SV=1 CANONICAL=A0A8V0YPI2-1" }, "locus": { "chromosome": "4", "start_pos": 88013706, "end_pos": 87993358, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010039642.1", "url": "https://www.ensembl.org/id/ENSGALT00010039642.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010022901.1", "url": "https://www.ensembl.org/id/ENSGALP00010022901.1" } ] } }, { "isoform_ac": "A0A8V0YVX1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPI2/entry#A0A8V0YVX1-1", "sequence": { "sequence": "MQSCEISGDSTDDPLSSGLRRTRQPRIVVIGAGLAGLSAAKALLESGFTDVTILEATDRIGGRVQSVKLGHATFELGATWIHGSHGNPVYHLAEDNGLLEETTDGERSVGRISLYSKNGVAYHLTNNGQRIPKDVVEEFSDLYNEVYNLTQEFFQRGKPVNAESQNSVGVFTRDVVRKRVKADPDDTEAVKRLKLAMIQQYLKVESCESSSHSMDEVSLSEFGEWTEIPGAHHIIPCGFIKIVEILARSIPESVIQLRKPVKCIHWNQSVSKEIERVADHNSDLPEEDRGSNVFVECEDCEFIPADHVIVTVSLGVLKKRHESLFHPRLPEEKVMAIEKLGINTTDKIFLEFEEPFWSSECNSIQFVWEDEAESESLTYPEELWYKKICSFDVLYPPERYGHVLSGWICGEEALIMEKCDDETVAETCTEMLRKFTGNPNIPKPRRILRSSWGSNPNFRGSYSYTQVGSSGADVEKLAKPLPYAESSKTTVSMARIS", "length": 497, "header": "tr|A0A8V0YVX1-1|A0A8V0YVX1_CHICK Computationally mapped isoform of Spermine oxidase OS=Gallus gallus OX=9031 GN=SMOX PE=4 SV=1 CANONICAL=A0A8V0YPI2-1" }, "locus": { "chromosome": "4", "start_pos": 88013706, "end_pos": 87994704, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010039640.1", "url": "https://www.ensembl.org/id/ENSGALT00010039640.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010022898.1", "url": "https://www.ensembl.org/id/ENSGALP00010022898.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "gga:422934", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422934", "resource": "KEGG Pathway" }, { "id": "R-GGA-141334", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-141334", "resource": "Reactome", "description": "PAOs oxidise polyamines to amines" }, { "id": "R-GGA-351200", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-351200", "resource": "Reactome", "description": "Interconversion of polyamines" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A480QKQ3-1", "protein_name": "Spermine oxidase", "gene_name": "SMOX", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MQSCESSGDSADDPLSCGLRRRGQPRVVVIGAGLAGLAAAKALLEQGFTNVTVLEASSRIGGRVQSVKLGHATFELGATWIHGSHGNPIYHLAEANGLLEETTDGERSVGRISLYSKNGVACYLTNHGRRIPKDVVEEFSDLYNEVYNLTQEFFRHGKPVNAESQNSVGVFTREEVRNRIRDDPDEPEATKRLKLAMIQQYLKVESCESSSHSMDEVSLSAFGEWTEIPGAHHIIPSGFMRVVELLAEGIPAHVIQLGKPVRCVHWNQASACPRGPEIEPRGEGDHNHDAGEGSQGGEEPPGERQDEDEQWPVLVECEDCEVIPADHVIVTVSLGVLKRQHASFFQPGLPTEKVVAIHRLGIGTTDKIFLEFEEPFWGPECNSLQFVWEDEAESRTLTYPPELWYRKICGFDVLYPPERYGHVLSGWICGEEALVMEKCDDEAVAEICTEMLRQFTGNPNIPKPRRILRSAWGSNPYFRGSYSYTQVGSSGADVEKLAKPLPYTESSKTAPMQVLFSGEATHRKYYSTTHGALLSGQREAARLIEMYQDLFQQGT", "length": 555 }, "evidence": [ { "id": "A0A8V0YPI2", "url": "https://omabrowser.org/oma/group/A0A8V0YPI2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "B8A458-1", "protein_name": "Peroxisomal N(1)-acetyl-spermine/spermidine oxidase", "gene_name": "smox", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MQSCEISSDSTDDPLSSALHGHRQPRIVVIGAGLAGLAATKTLLENGFTNVTVLEASDRIGGRVQSIQHGKTTLELGATWIHGANGNPVYHLAEDNGLLEHTTEEERSVGRISLYAKNGVAHYQTNNGKRIPKDLVEEFSDLYNEVYELTQEFFQNGKPVGAESQNSVGIFTRDVVRKKIMLDPYDSESIRKLKLSMLQQYLKVESCESSSPNMDEVSLSEFGEWTEIPGAHHVIPTGFIKVVEILAQDIPSCVLHLSKPVRRVHWNCSSQDAEEFGDQVDHNQDQRPSPSPVCVECEDGERLLADHVILTASLGVLKKAHKTLFSPGLPQDKAQAIQKLGISTTDKIFLEFAEPFWSPECNSIQFVWEDEAQLESQAYPEELWYRKICSFDVLYPPERYGHMLSGWICGEEALRMERCDDETVAEICTELLRQFTGNQNIPKPRRILRSSWGSNPYIRGSYSFTRVGSSGRDVEKLAEPLPYIKNTKAPPLQVLFAGEATHRKYYSTTHGALLSGQREANRLMELYQYSCAETTKPNI", "length": 539 }, "evidence": [ { "id": "A0A8V0YPI2", "url": "https://omabrowser.org/oma/group/A0A8V0YPI2/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "E1B7M5-1", "protein_name": "Spermine oxidase", "gene_name": "SMOX", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MQSCESSGDSADDPLSRGLRRRGQPRVVVIGAGLAGLAAAKALLEQGFTDVTVLEASSRIGGRVQSVKLGHATFELGATWIHGSHGNPIYHLAEANGLLEETTDGERSVGRISLYSKNGVACYLTNRGCRIPKDVVEEFSDLYNEVYNLTQEFFRHGKPVNAESQNSVGVFTREEVRNRIRDDPDDPEATKRLKLAMIQQYLKVESCESSSHSMDEVSLSAFGEWTEIPGAHHVIPSGFMRVVELLAEGIPAHVIQLGKPVRCVHWDQASSRPRGPEIEPRDEGDHNHDAGEGSQGGEEPREERQDEDEQWPVVVECEDCEVIPADHVIVTVSLGVLKRQHASFFRPGLPAEKVAAIHRLGIGTTDKIFLEFEEPFWGPECNSLRFVWEDEAESCTLTYPPELWYRKICGFDVLYPPERYGHVLSGWICGEEALVMEKCDDEAVAEICTEMLRQFTGNPNIPKPRRILRSAWGSNPYFRGSYSYTQVGSSGADVEKLAKPLPYTESSKTAPMQVLFSGEATHRKYYSTTHGALLSGQREAARLIEMYRDLFQQGT", "length": 555 }, "evidence": [ { "id": "A0A8V0YPI2", "url": "https://omabrowser.org/oma/group/A0A8V0YPI2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q99K82-1", "protein_name": "Spermine oxidase", "gene_name": "Smox", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MQSCESSGDSADDPLSRGLRRRGQPRVVVIGAGLAGLAAARALLEQGFTDVTVLEASSHIGGRVQSVRLGDTTFELGATWIHGSHGNPIYQLAEANGLLEETTDGERSVGRISLYSKNGVACYLTNRGCRIPKDVVEEFSDLYNEVYNMTQEFFRHGKPVNAESQNSVGVFTREKVRNRIRDDPDDTEATKRLKLAMIQQYLKVESCESSSHSIDEVSLSAFGEWTEIPGAHHIIPSGFMRVVELLAEGIPPHVIQLGKPVRCIHWDQASAHPRGPEIEPRGEGDHNHDTGEGGQSGENPQQGRWDEDEPWPVVVECEDCEVIPADHVIVTVSLGVLKRQYTSFFRPCLPTEKVAAIHRLGIGTTDKIFLEFEEPFWGPECNSLQFVWEDEAESCTLTYPPELWYRKICGFDVLYPPERYGHVLSGWICGEEALVMERCDDEAVAEICTEMLRQFTGNPNIPKPRRILRSAWGSNPYFRGSYSYTQVGSSGADVEKLAKPLPYTESSKTAPMQVLFSGEATHRKYYSTTHGALLSGQREAARLIEMYRDLFQQGP", "length": 555 }, "evidence": [ { "id": "A0A8V0YPI2", "url": "https://omabrowser.org/oma/group/A0A8V0YPI2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9NWM0-1", "protein_name": "Spermine oxidase", "gene_name": "SMOX", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MQSCESSGDSADDPLSRGLRRRGQPRVVVIGAGLAGLAAAKALLEQGFTDVTVLEASSHIGGRVQSVKLGHATFELGATWIHGSHGNPIYHLAEANGLLEETTDGERSVGRISLYSKNGVACYLTNHGRRIPKDVVEEFSDLYNEVYNLTQEFFRHDKPVNAESQNSVGVFTREEVRNRIRNDPDDPEATKRLKLAMIQQYLKVESCESSSHSMDEVSLSAFGEWTEIPGAHHIIPSGFMRVVELLAEGIPAHVIQLGKPVRCIHWDQASARPRGPEIEPRGEGDHNHDTGEGGQGGEEPRGGRWDEDEQWSVVVECEDCELIPADHVIVTVSLGVLKRQYTSFFRPGLPTEKVAAIHRLGIGTTDKIFLEFEEPFWGPECNSLQFVWEDEAESHTLTYPPELWYRKICGFDVLYPPERYGHVLSGWICGEEALVMEKCDDEAVAEICTEMLRQFTGNPNIPKPRRILRSAWGSNPYFRGSYSYTQVGSSGADVEKLAKPLPYTESSKTAPMQVLFSGEATHRKYYSTTHGALLSGQREAARLIEMYRDLFQQGT", "length": 555 }, "evidence": [ { "id": "A0A8V0YPI2", "url": "https://omabrowser.org/oma/group/A0A8V0YPI2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VHN8-1", "protein_name": "Amine oxidase domain-containing protein", "gene_name": "Dmel\\CG8032", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MGDKEEPVTPAPSPTEEGMANIGSAGAGDQPQTSGNNTNVKIVIIGAGMAGLSAANHLLQNGCDDFLILEARGRVGGRIVSIPLSNNQKIELGANWIHGVLGNPIFELAVQHGLVSVVNVPKPHKVVATTEDGHQVPFNILQEIYEAYVCFLRRCDEYFLCQYSPPPDIHSVGEHINYEIEIYLSGVQDPKEKRLKQSIFNCLLKRETCITGCNNMDEVDLLELGSYTELQGGNIVLPTGYSSILRPLGAQIAKQSILTKCPVKKIHWKRKKTFTGLETVDENSEDEHSDDSERTVTEVPTGEIRGASVESNTSSNCDYPAGNVRIDCEDGRVFHAAHVICTIPLGVLKNTHRTLFDPVLPQYKQESIENLMFGTVDKIFLEYERPFLSADISEIMLLWDDDKRDMNSSEEELASEAYLSKNWFKKIYSFAKVTDTLLLGWVSGREAEYMEKLDHEAVAEKCTEILRNFLQDPYVPKPKRCVCTSWKSQDFTGGAYTSIPVGATQEDIENLAQPLYATPQAMKPAIVFAGEHTHSSFYSTVHGAYLSGRTAAQHLLASDEPDEIIMESDGSDLSAWIQGIALD", "length": 583 }, "evidence": [ { "id": "A0A8V0YPI2", "url": "https://omabrowser.org/oma/group/A0A8V0YPI2/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "oxidoreductase activity", "id": "GO:0016491", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016491", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPI2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPI2" } ], "pmid": "" }, { "name": "polyamine oxidase activity", "id": "GO:0046592", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046592", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPI2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPI2" } ], "pmid": "" }, { "name": "N(1)-acetylpolyamine oxidase (3-acetamidopropanal-forming) activity", "id": "GO:0052903", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0052903", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPI2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPI2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPI2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPI2" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPI2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPI2" } ], "pmid": "" }, { "name": "peroxisome", "id": "GO:0005777", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005777", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPI2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPI2" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPI2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPI2" } ], "pmid": "" }, { "name": "nuclear membrane", "id": "GO:0031965", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031965", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPI2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPI2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "spermine catabolic process", "id": "GO:0046208", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046208", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPI2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPI2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 148, "end_pos": 150, "annotation": "n_glycosylation_sequon" }, { "start_pos": 267, "end_pos": 269, "annotation": "n_glycosylation_sequon" }, { "start_pos": 343, "end_pos": 345, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "25800", "name": "", "equation": "N(1)-acetylspermine + O2 + H2O = 3-acetamidopropanal + spermidine + H2O2", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YPI2-1", "A0A8V0ZQU7-1" ], "evidence": [ { "id": "25800", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/25800" } ] }, { "id": "25812", "name": "", "equation": "N(1)-acetylspermidine + O2 + H2O = 3-acetamidopropanal + putrescine + H2O2", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YPI2-1", "A0A8V0ZQU7-1" ], "evidence": [ { "id": "25812", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/25812" } ] }, { "id": "25868", "name": "", "equation": "N(1),N(12)-diacetylspermine + O2 + H2O = 3-acetamidopropanal + N(1)-acetylspermidine + H2O2", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YPI2-1", "A0A8V0ZQU7-1" ], "evidence": [ { "id": "25868", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/25868" } ] }, { "id": "R-GGA-141341", "name": "SMOX-3 oxidises SPN to SPM", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, peroxisomal matrix", "input_participant_list": [ "R-ALL-141342" ], "output_participant_list": [ "R-ALL-141328" ], "enzyme_list": [ "A0A8V0YPI2-1" ], "evidence": [ { "id": "R-GGA-141341", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-141341" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-141328", "participant_name": "3APAL [peroxisomal matrix]", "crossref": [ { "id": "ZINC000001529387", "database": "ZINC", "url": "" }, { "id": "C02229", "database": "COMPOUND", "url": "" }, { "id": "58374", "database": "ChEBI", "url": "" }, { "id": "HMDB0062210", "database": "HMDB Metabolite", "url": "" } ] }, { "participant_id": "R-ALL-141342", "participant_name": "SPN [peroxisomal matrix]", "crossref": [ { "id": "45725", "database": "ChEBI", "url": "" }, { "id": "ZINC000001532734", "database": "ZINC", "url": "" }, { "id": "C00750", "database": "COMPOUND", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A0A8V0YPI2", "gene_name": "SMOX", "activity": [ { "ec_number": "1.5.3.13", "activity": "N(1)-acetylspermine + O2 + H2O = 3-acetamidopropanal + spermidine + H2O2.", "evidence": [ { "id": "A0A8V0YPI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPI2" } ] }, { "ec_number": "1.5.3.13", "activity": "", "evidence": [ { "id": "A0A8V0YPI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPI2" } ] } ] }, { "uniprot_ac": "A0A8V0ZQU7", "gene_name": "PAOX", "activity": [ { "ec_number": "1.5.3.13", "activity": "N(1)-acetylspermine + O2 + H2O = 3-acetamidopropanal + spermidine + H2O2.", "evidence": [ { "id": "A0A8V0ZQU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQU7" } ] }, { "ec_number": "1.5.3.13", "activity": "", "evidence": [ { "id": "A0A8V0ZQU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQU7" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YPI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPI2" }, { "id": "PF01593", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01593" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Amine oxidase", "eco_id": "ECO_0000259", "start_pos": 34, "end_pos": 532, "start_aa": "Leu", "end_aa": "Ile", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "1.5.3.13", "ec_name": "N(1)-acetylspermine + O2 + H2O = 3-acetamidopropanal + spermidine + H2O2.", "evidence": [ { "id": "1.5.3.13", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:1.5.3.13" }, { "id": "1.5.3.13", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=1.5.3.13" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 148, "end_pos": 150 }, { "start_pos": 267, "end_pos": 269 }, { "start_pos": 343, "end_pos": 345 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YPK9-1", "uniprot_ac": "A0A8V0YPK9", "uniprot_id": "A0A8V0YPK9_CHICK", "mass": { "chemical_mass": 39270.0, "monoisotopic_mass": 39270.0 }, "refseq": {}, "gene_names": [ { "name": "DNAH14", "type": "recommended", "evidence": [ { "id": "A0A8V0YPK9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPK9" } ] } ], "protein_names": [ { "name": "Dynein axonemal heavy chain 14", "type": "synonym", "evidence": [ { "id": "A0A8V0YPK9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPK9/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPK9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPK9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "DNAH14", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPK9", "locus": {} } ], "crossref": [ { "id": "A0A8V0YPK9", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YPK9", "database": "AlphaFoldDB", "categories": [] }, { "id": "A0A8V0YPK5", "url": "https://www.orthodb.org/?gene=A0A8V0YPK5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YPK9", "url": "https://www.orthodb.org/?gene=A0A8V0YPK9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YPK5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPK5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YPK5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPK5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YPK9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPK9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YPK9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPK9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDGQNKMLKEQLESHLRFEADRAEVLLMAKGRCIMCGPAGSRRKHSTEPASPVEKYSILHTAVHRARTETKHKAEVNEEGGVCPSKVLPKQHKDEREESVCEPTGRSGHEAMEVKRSIAKVASIISEDNNGTSPSSTVYDRRTEIQKSVLEPSCLKKVCEHPKVECSPKKPMGAKVYSYDETEPTDDDVIMHILRLRGKLGWQTKLPSWEYLAREADVARLQKLALTRPLLPRDSGEYIYCLQKHKNNLRVPYNPYNLQAVSASTAMHSKEYWTVTASFVSKFHVNQKLGEMEATPVPRWLRERHLYYRLLNLNLFSNFRMKKFILHWKINAGRSKANKSKSV", "length": 343, "header": "tr|A0A8V0YPK9-1|A0A8V0YPK9_CHICK Isoform 1 of Dynein axonemal heavy chain 14 OS=Gallus gallus OX=9031 GN=DNAH14 PE=4 SV=1 CANONICAL=A0A8V0YPK9-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YPK5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPK9/entry#A0A8V0YPK5-1", "sequence": { "sequence": "MEAPSLEDKGCQPQMDGQNKMLKEQLESHLRFEADRAEVLLMAKGRCIMCGPAGSRRKHSTEPASPVEKYSILHTAVHRARTETKHKAEVNEEGGVCPSKVLPKQHKDEREESVCEPTGRSGHEAMEVKRSIAKVASIISEDNNGTSPSSTVYDRRTEIQKSVLEPSCLKKVCEHPKVECSPKKPMGAKVYSYDETEPTDDDVIMHILRLRGKLGWQTKLPSWEYLAREADVARLQKLALTRPLLPRDSGEYIYCLQKHKNNLRVPYNPYNLQAVSASTAMHSKEYWTVTASFVSKFHVNQKLGEMEATPVPRWLRERHLYYRLLNLNLFSNFSNVTEK", "length": 339, "header": "tr|A0A8V0YPK5-1|A0A8V0YPK9_CHICK Computationally mapped isoform of Dynein axonemal heavy chain 14 OS=Gallus gallus OX=9031 GN=DNAH14 PE=4 SV=1 CANONICAL=A0A8V0YPK9-1" }, "locus": { "chromosome": "3", "start_pos": 17134678, "end_pos": 17123747, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010039667.1", "url": "https://www.ensembl.org/id/ENSGALT00010039667.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010022926.1", "url": "https://www.ensembl.org/id/ENSGALP00010022926.1" } ] } }, { "isoform_ac": "A0A8V0YPK9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPK9/entry#A0A8V0YPK9-1", "sequence": { "sequence": "MDGQNKMLKEQLESHLRFEADRAEVLLMAKGRCIMCGPAGSRRKHSTEPASPVEKYSILHTAVHRARTETKHKAEVNEEGGVCPSKVLPKQHKDEREESVCEPTGRSGHEAMEVKRSIAKVASIISEDNNGTSPSSTVYDRRTEIQKSVLEPSCLKKVCEHPKVECSPKKPMGAKVYSYDETEPTDDDVIMHILRLRGKLGWQTKLPSWEYLAREADVARLQKLALTRPLLPRDSGEYIYCLQKHKNNLRVPYNPYNLQAVSASTAMHSKEYWTVTASFVSKFHVNQKLGEMEATPVPRWLRERHLYYRLLNLNLFSNFRMKKFILHWKINAGRSKANKSKSV", "length": 343, "header": "tr|A0A8V0YPK9-1|A0A8V0YPK9_CHICK Isoform 1 of Dynein axonemal heavy chain 14 OS=Gallus gallus OX=9031 GN=DNAH14 PE=4 SV=1 CANONICAL=A0A8V0YPK9-1" }, "locus": { "chromosome": "3", "start_pos": 17132029, "end_pos": 17123679, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010039672.1", "url": "https://www.ensembl.org/id/ENSGALT00010039672.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010022931.1", "url": "https://www.ensembl.org/id/ENSGALP00010022931.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 130, "end_pos": 132, "annotation": "n_glycosylation_sequon" }, { "start_pos": 338, "end_pos": 340, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 130, "end_pos": 132 }, { "start_pos": 338, "end_pos": 340 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YPK8-1", "uniprot_ac": "A0A8V0YPK8", "uniprot_id": "A0A8V0YPK8_CHICK", "mass": { "chemical_mass": 81275.0, "monoisotopic_mass": 81275.0 }, "refseq": { "ac": "XP_422209", "name": "olfactomedin-like protein 2B", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_422209" }, "gene_names": [ { "name": "OLFML2B", "type": "recommended", "evidence": [ { "id": "A0A8V0YPK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPK8" } ] }, { "name": "OLFML2B", "type": "synonym", "evidence": [ { "id": "XP_422209", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_422209" } ] } ], "protein_names": [ { "name": "Olfactomedin like 2B", "type": "synonym", "evidence": [ { "id": "A0A8V0YPK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPK8/entry#names_and_taxonomy" } ] }, { "name": "olfactomedin-like protein 2B", "type": "synonym", "evidence": [ { "id": "XP_422209", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_422209" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052539.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_422209.6. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_422209", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_422209" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPK8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPK8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "OLFML2B", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPK8", "locus": { "chromosome": "8", "start_pos": 3791658, "end_pos": 3801521, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012958", "url": "https://www.ensembl.org/id/ENSGALG00010012958" } ] } } ], "crossref": [ { "id": "A0A8V0YPK8", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YPK8", "database": "AlphaFoldDB", "categories": [] }, { "id": "424366", "url": "https://www.ncbi.nlm.nih.gov/gene/424366", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003112", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003112", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050605", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050605", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:424366", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424366", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "SEPDPME", "url": "https://omabrowser.org/oma/group/SEPDPME/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YBD7", "url": "https://www.orthodb.org/?gene=A0A8V0YBD7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YPK8", "url": "https://www.orthodb.org/?gene=A0A8V0YPK8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23192", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23192", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23192:SF37", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23192:SF37", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02191", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02191", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_422209", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_422209", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YBD7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBD7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YBD7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBD7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YPK8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPK8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YPK8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPK8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MARPLPLLLCLAALGAGCRAGPAPTGTAGPSAEPLQDEADNQENILSQLLGDYDKVKAVSEGSDCRCKCLVRPLGRGACQRINQGSFRAEDFYTVETITSGPGCKCACVAPPSALNPCEGDFRLQKLREADSGDLKLSSIVEMLESAFYGLDLLKLHSVTTKLVGRVERLEESMTRNATRAGVNVEEPLSEPQRRGGENCSGLISNSLADIESSLQRDAEAAYVHPEGKYEERFLKDETISQQINSVESLAGLHLAPEEGKPEQLLQRKLSPRSRPPSKPTIVRGVTYYKAQSSESDNDIEEQQDELFSGDNTVDLLIEDQLLRPSGRAGEAVRKPSPVGWPPTPSIEPSTAPTTLPLSTAASVGPTPEPTTASLPPPTMETATTASVLPEEETPQLPTASASVVALTATESPPVANSSVPSPAVAATTTQTSWDVGMSPEPGTGSSAGPPEQASTPPPLSTTIPATPKQALEEEDIRNIIGRCKDTLSTISGPTTQNTYGRNEGAWMKDPLAKEERIYVTNYYYGNTLVEFRNLDNFKQGRWSNSYKLPYSWIGTGHVVYNGSFYYNRAFTRNIIKYDLKQRYVAAWAMLHDVAYEESTPWRWRGHSDVDFAVDENGLWVIYPAISYEGFNQEVIVLSKLNAADLSTQKETTWRTGLRKNFYGNCFVICGVLYAVDSYNKRNANISYAFDTHTNTQIIPRLLFENEYAYTTQIDYNPKDRLLYAWDNGHQVTYHVIFAY", "length": 740, "header": "tr|A0A8V0YPK8-1|A0A8V0YPK8_CHICK Isoform 1 of Olfactomedin like 2B OS=Gallus gallus OX=9031 GN=OLFML2B PE=4 SV=1 CANONICAL=A0A8V0YPK8-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YBD7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPK8/entry#A0A8V0YBD7-1", "sequence": { "sequence": "MARPLPLLLCLAPLQDEADNQENILSQLLGDYDKVKAVSEGSDCRCKCLVRPLGRGACQRINQGSFRAEDFYTVETITSGPGCKCACVAPPSALNPCEGDFRLQKLREADSGDLKLSSIVEMLESAFYGLDLLKLHSVTTKLVGRVERLEESMTRNATRAGVNVEEPLSEPQRRGGENCSGLISNSLADIESSLQRDAEAAYVHPEGKYEERFLKDETISQQINSVESLAGLHLAPEEGKPEQLLQRKLSPRSRPPSKPTIVRGVTYYKAQSSESDNDIEEQQDELFSGDNTVDLLIEDQLLRPSGRAGEAVRKPSPVGWPPTPSIEPSTAPTTLPLSTAASVGPTPEPTTASLPPPTMETATTASVLPEEETPQLPTASASVVALTATESPPVANSSVPSPAVAATTTQTSWDVGMSPEPGTGSSAGPPEQASTPPPLSTTIPATPKQALEEEDIRNIIGRCKDTLSTISGPTTQNTYGRNEGAWMKDPLAKEERIYVTNYYYGNTLVEFRNLDNFKQGRWSNSYKLPYSWIGTGHVVYNGSFYYNRAFTRNIIKYDLKQRYVAAWAMLHDVAYEESTPWRWRGHSDVDFAVDENGLWVIYPAISYEGFNQEVIVLSKLNAADLSTQKETTWRTGLRKNFYGNCFVICGVLYAVDSYNKRNANISYAFDTHTNTQIIPRLLFENEYAYTTQIDYNPKDRLLYAWDNGHQVTYHVIFAY", "length": 719, "header": "tr|A0A8V0YBD7-1|A0A8V0YBD7_CHICK Computationally mapped isoform of Olfactomedin like 2B OS=Gallus gallus OX=9031 GN=OLFML2B PE=4 SV=1 CANONICAL=A0A8V0YPK8-1" }, "locus": { "chromosome": "8", "start_pos": 3801433, "end_pos": 3792441, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031089.1", "url": "https://www.ensembl.org/id/ENSGALT00010031089.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018083.1", "url": "https://www.ensembl.org/id/ENSGALP00010018083.1" } ] } }, { "isoform_ac": "A0A8V0YPK8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPK8/entry#A0A8V0YPK8-1", "sequence": { "sequence": "MARPLPLLLCLAALGAGCRAGPAPTGTAGPSAEPLQDEADNQENILSQLLGDYDKVKAVSEGSDCRCKCLVRPLGRGACQRINQGSFRAEDFYTVETITSGPGCKCACVAPPSALNPCEGDFRLQKLREADSGDLKLSSIVEMLESAFYGLDLLKLHSVTTKLVGRVERLEESMTRNATRAGVNVEEPLSEPQRRGGENCSGLISNSLADIESSLQRDAEAAYVHPEGKYEERFLKDETISQQINSVESLAGLHLAPEEGKPEQLLQRKLSPRSRPPSKPTIVRGVTYYKAQSSESDNDIEEQQDELFSGDNTVDLLIEDQLLRPSGRAGEAVRKPSPVGWPPTPSIEPSTAPTTLPLSTAASVGPTPEPTTASLPPPTMETATTASVLPEEETPQLPTASASVVALTATESPPVANSSVPSPAVAATTTQTSWDVGMSPEPGTGSSAGPPEQASTPPPLSTTIPATPKQALEEEDIRNIIGRCKDTLSTISGPTTQNTYGRNEGAWMKDPLAKEERIYVTNYYYGNTLVEFRNLDNFKQGRWSNSYKLPYSWIGTGHVVYNGSFYYNRAFTRNIIKYDLKQRYVAAWAMLHDVAYEESTPWRWRGHSDVDFAVDENGLWVIYPAISYEGFNQEVIVLSKLNAADLSTQKETTWRTGLRKNFYGNCFVICGVLYAVDSYNKRNANISYAFDTHTNTQIIPRLLFENEYAYTTQIDYNPKDRLLYAWDNGHQVTYHVIFAY", "length": 740, "header": "tr|A0A8V0YPK8-1|A0A8V0YPK8_CHICK Isoform 1 of Olfactomedin like 2B OS=Gallus gallus OX=9031 GN=OLFML2B PE=4 SV=1 CANONICAL=A0A8V0YPK8-1" }, "locus": { "chromosome": "8", "start_pos": 3801433, "end_pos": 3792441, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031090.1", "url": "https://www.ensembl.org/id/ENSGALT00010031090.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018084.1", "url": "https://www.ensembl.org/id/ENSGALP00010018084.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 344, "start_aa": "Thr", "end_pos": 344, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr344", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 367, "start_aa": "Thr", "end_pos": 367, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr367", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:424366", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424366", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8N7UVJ6-1", "protein_name": "Olfactomedin-like protein 2B isoform X2", "gene_name": "olfml2bb", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MGLLLYIFCCVFCLTRANVEQQATDNTDNRATLEDEMDNQENILTQLIGDYDKVKTLSEGSDCQCKCVVRPLSRSACKRIEEGQAKTEDFYTVETVTAGPNCKKCACIAPPSALNPCEGDFRFKKLQEAGQDDIKLSNIMDLLEGSFYGMDLLKLHSVTTKLLERVDNIEKSFSGNLTKEKVSVKGEKGQGKGARSNQRQEKKKRLSVLEPSLQKNAAAAFAHTERKYEEKFVGNQGPSKPVLKKSKSEGQEEQHKPAKTKADAKNMSLRSMTFYKANRMEDSEGEERIGATVAHEVVSGDESVDLIIEDQLHKQGLNTPVTTPEATVTVTQSTTINLNTQNFTTARMSNVTKQTQGQSVKAMMSSTITTERPTMPTSTTSTSTMTPGTNTTTIATPLVVPKQLASVTVPIKKSKLSWDEVTTQKSTTTLKTKDHGICKDTLASISDPVTHNKYGKNEGAWMKDPKGNGKVVYVTDYYYGNQLLEFRDIDTFKQGQVSNSYKLPYNWIGTGHVVYSGSFFYNRAFSRDIIRFDLRLRYVAAWTTLHDAILEEEEAPWTWGGHSDIDFSVDESGLWLVYPALDDEGFHQEVIILSKLRASDLQKEKSWRTGLRRNYYGNCFVICGVLYAVDSFERTHANISYAFDTHTHTQMIPRLPFINNYTYTTQIDYNPKERMLYAWDNGHQVTYDVIFAY", "length": 693 }, "evidence": [ { "id": "A0A8V0YPK8", "url": "https://omabrowser.org/oma/group/A0A8V0YPK8/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q3V1G4-1", "protein_name": "Olfactomedin-like protein 2B", "gene_name": "Olfml2b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAYPLPLVLCFALVVAQVWGSTTPPTGTSEPPDVQTVEPTEDDILQNEADNQENVLSQLLGDYDKVKAVSEGSDCQCKCVVRPLGRDACQRINQGASRKEDFYTVETITSGSSCKCACVAPPSAVNPCEGDFRLQKLREADSRDLKLSTIIDLLEGAFYGLDLLKLHSVTTKLVGRVDKLEEEVSKNLTKENEQIKEDVEEIRTELNKRGKENCSDNTLESMPDIRSALQRDAAAAYAHPEYEERFLQEETVSQQINSIELLRTQPLVPPAAMKPQRPLQRQVHLRGRLASKPTVIRGITYYKAKVSEEENDIEEQHDELFSGDSGVDLLIEDQLLRQEDLLTSATRRPATTRHTAAVTTDASIQAAASSSEPAQASASASSFVEPAPQASDRELLATPQTTTVFPEPTEVMPSTQVSPTTVAHTAVQPLPAMVPGDIFVEALPLVPLLPDTVGTDMPEEEGTAGQEATSAGPILSPEEEDDIRNVIGRCKDTLSTITGPTTQNTYGRNEGAWMKDPLAKDDRIYVTNYYYGNTLVEFRNLENFKQGRWSNSYKLPYSWIGTGHVVYNGAFYYNRAFTRNIIKYDLKQRYVAAWAMLHDVAYEEATPWRWQGHSDVDFAVDENGLWLIYPALDDEGFNQEVIVLSKLNAVDLSTQKETTWRTGLRRNFYGNCFVICGVLYAVDSYNQRNANISYAFDTHTNTQIVPRLLFENEYSYTTQIDYNPKDRLLYAWDNGHQVTYHVIFAY", "length": 746 }, "evidence": [ { "id": "A0A8V0YPK8", "url": "https://omabrowser.org/oma/group/A0A8V0YPK8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPK8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPK8" } ], "pmid": "" }, { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPK8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPK8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPK8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPK8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 177, "end_pos": 179, "annotation": "n_glycosylation_sequon" }, { "start_pos": 199, "end_pos": 201, "annotation": "n_glycosylation_sequon" }, { "start_pos": 417, "end_pos": 419, "annotation": "n_glycosylation_sequon" }, { "start_pos": 562, "end_pos": 564, "annotation": "n_glycosylation_sequon" }, { "start_pos": 685, "end_pos": 687, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YPK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPK8" }, { "id": "PS51132", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51132" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Olfactomedin-like", "eco_id": "ECO_0000259", "start_pos": 483, "end_pos": 740, "start_aa": "Arg", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 344, 367 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 177, "end_pos": 179 }, { "start_pos": 199, "end_pos": 201 }, { "start_pos": 417, "end_pos": 419 }, { "start_pos": 562, "end_pos": 564 }, { "start_pos": 685, "end_pos": 687 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YPM0-1", "uniprot_ac": "A0A8V0YPM0", "uniprot_id": "A0A8V0YPM0_CHICK", "mass": { "chemical_mass": 25877.0, "monoisotopic_mass": 25877.0 }, "refseq": {}, "gene_names": [ { "name": "SPINK7", "type": "recommended", "evidence": [ { "id": "A0A8V0YPM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPM0" } ] } ], "protein_names": [ { "name": "Serine peptidase inhibitor, Kazal type 7 (putative)", "type": "synonym", "evidence": [ { "id": "A0A8V0YPM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPM0/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPM0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPM0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SPINK7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPM0", "locus": { "chromosome": "13", "start_pos": 10184657, "end_pos": 10175846, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010014724", "url": "https://www.ensembl.org/id/ENSGALG00010014724" } ] } } ], "crossref": [ { "id": "A0A8V0YPM0", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YPM0", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00104", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00104", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd01327", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01327", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR002350", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002350", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036058", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036058", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YPM0", "url": "https://www.orthodb.org/?gene=A0A8V0YPM0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21312", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21312", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21312:SF28", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21312:SF28", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00050", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00050", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YPM0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPM0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YPM0-1", "url": 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Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052540.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_046754455", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046754455" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPP0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPP0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "GP5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPP0", "locus": { "chromosome": "9", "start_pos": 12587043, "end_pos": 12578771, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010014668", "url": "https://www.ensembl.org/id/ENSGALG00010014668" } ] } } ], "crossref": [ { "id": "124417079", "url": "https://www.ncbi.nlm.nih.gov/gene/124417079", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000483", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000483", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001611", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001611", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003591", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003591", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050541", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050541", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "QGPEYVH", "url": "https://omabrowser.org/oma/group/QGPEYVH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR24369", "url": 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"id": "1.11.1.9", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:1.11.1.9" }, { "id": "1.11.1.9", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=1.11.1.9" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YPQ6-1", "uniprot_ac": "A0A8V0YPQ6", "uniprot_id": "A0A8V0YPQ6_CHICK", "mass": { "chemical_mass": 83324.0, "monoisotopic_mass": 83324.0 }, "refseq": { "ac": "XP_040561613", "name": "dynein axonemal intermediate chain 7 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040561613" }, "gene_names": [ { "name": "DNAI7", "type": "recommended", "evidence": [ { "id": "A0A8V0YPQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPQ6" } ] }, { "name": "DNAI7", "type": "synonym", "evidence": [ { "id": "XP_040561613", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040561613" } ] } ], "protein_names": [ { "name": "Dynein axonemal intermediate chain 7", "type": "recommended", "evidence": [ { "id": "A0A8V0YPQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPQ6/entry#names_and_taxonomy" } ] }, { "name": "dynein axonemal intermediate chain 7 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_040561613", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040561613" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040561613", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040561613" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPQ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPQ6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "DNAI7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPQ6", "locus": { "chromosome": "1", "start_pos": 67241359, "end_pos": 67260450, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010014154", "url": "https://www.ensembl.org/id/ENSGALG00010014154" } ] } } ], "crossref": [ { "id": "A0A8V0YPQ6", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YPQ6", "database": "AlphaFoldDB", "categories": [] }, { "id": "418206", "url": "https://www.ncbi.nlm.nih.gov/gene/418206", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR023247", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023247", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR031826", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031826", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "FTRCEKT", "url": "https://omabrowser.org/oma/group/FTRCEKT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YPQ6", "url": "https://www.orthodb.org/?gene=A0A8V0YPQ6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YUQ8", "url": "https://www.orthodb.org/?gene=A0A8V0YUQ8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YUR5", "url": "https://www.orthodb.org/?gene=A0A8V0YUR5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR20929", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR20929", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR20929:SF11", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR20929:SF11", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15927", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15927", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_040561613", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040561613", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YPQ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPQ6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YPQ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPQ6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YUQ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUQ8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YUQ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUQ8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YUR5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUR5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YUR5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUR5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGPKKQKKSGGKNKVGKAEKLRLQKEEEERRLQEEEEARLQAEQEEAARLEKERIERERMKKLEAKDQERREDELAELNSLQEKFVCAQRWKTEYRAYTKWEHYIACDGSPDPTVLQEINTFMNLWREDQNEDIQFVMEKGEQVLNLIEKLQFLLLDVPPSEITEKETAQYQETILELENLLHQKYNEATEHLLKSAIMYEDSDTGNMQTVIKDKNVTFCIWANLKKKVRFKNHVFCDTHHGFDLPKSLAVSSIAVRILHTHYDHVSPLWLQCQRVPRLEVLDSQELTQHSQDNAGEPEEEEKEAKEEPNVTAEEETLPDERNSAISFRGNTNSIADTNEVTEEETEKKSENLEVTPEVQIPQMEEKTSEEEEMITDESTVDLQQFVPVGGVYRIDGLQLPPQVQQINSWCVVELLDGGLEAYPYPPQESEDTPHPPIQITLGLPDSVIYWKEPMIARWDPAGKQWRTDGISNITYETQEGNITFEIDAFYTIAFLQDIHLNMPYQAWELRPTSTDEAVFVITAVFAEVQIQIKGNQCMLAAVVVEEKNVLSHLIGKWMCPVTLRRALKKCGLNIFPEEYSYKYVCVNQKAPITEFRAYRQIALVASAFAFGWSKWNLESGQDQVVFKVSEHLKADFVKDEDWSLYMFNGQRAQKLKITEASEAFSMELEEDTEFHSTLYHMLKDFASKEAIDKVNTANFLFVDAVYQLLLATRVLMYS", "length": 719, "header": "tr|A0A8V0YPQ6-1|A0A8V0YPQ6_CHICK Isoform 1 of Dynein axonemal intermediate chain 7 OS=Gallus gallus OX=9031 GN=DNAI7 PE=3 SV=1 CANONICAL=A0A8V0YPQ6-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YPQ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPQ6/entry#A0A8V0YPQ6-1", "sequence": { "sequence": "MGPKKQKKSGGKNKVGKAEKLRLQKEEEERRLQEEEEARLQAEQEEAARLEKERIERERMKKLEAKDQERREDELAELNSLQEKFVCAQRWKTEYRAYTKWEHYIACDGSPDPTVLQEINTFMNLWREDQNEDIQFVMEKGEQVLNLIEKLQFLLLDVPPSEITEKETAQYQETILELENLLHQKYNEATEHLLKSAIMYEDSDTGNMQTVIKDKNVTFCIWANLKKKVRFKNHVFCDTHHGFDLPKSLAVSSIAVRILHTHYDHVSPLWLQCQRVPRLEVLDSQELTQHSQDNAGEPEEEEKEAKEEPNVTAEEETLPDERNSAISFRGNTNSIADTNEVTEEETEKKSENLEVTPEVQIPQMEEKTSEEEEMITDESTVDLQQFVPVGGVYRIDGLQLPPQVQQINSWCVVELLDGGLEAYPYPPQESEDTPHPPIQITLGLPDSVIYWKEPMIARWDPAGKQWRTDGISNITYETQEGNITFEIDAFYTIAFLQDIHLNMPYQAWELRPTSTDEAVFVITAVFAEVQIQIKGNQCMLAAVVVEEKNVLSHLIGKWMCPVTLRRALKKCGLNIFPEEYSYKYVCVNQKAPITEFRAYRQIALVASAFAFGWSKWNLESGQDQVVFKVSEHLKADFVKDEDWSLYMFNGQRAQKLKITEASEAFSMELEEDTEFHSTLYHMLKDFASKEAIDKVNTANFLFVDAVYQLLLATRVLMYS", "length": 719, "header": "tr|A0A8V0YPQ6-1|A0A8V0YPQ6_CHICK Isoform 1 of Dynein axonemal intermediate chain 7 OS=Gallus gallus OX=9031 GN=DNAI7 PE=3 SV=1 CANONICAL=A0A8V0YPQ6-1" }, "locus": { "chromosome": "1", "start_pos": 67260385, "end_pos": 67241429, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034018.1", "url": "https://www.ensembl.org/id/ENSGALT00010034018.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019997.1", "url": "https://www.ensembl.org/id/ENSGALP00010019997.1" } ] } }, { "isoform_ac": "A0A8V0YUQ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPQ6/entry#A0A8V0YUQ8-1", "sequence": { "sequence": "MSGGKNKVGKAEKLRLQKEEEERRLQEEEEARLQAEQEEAARLEKERIERERMKKLEAKDQERREDELAELNSLQEKFVCAQRWKTEYRAYTKWEHYIACDGSPDPTVLQEINTFMNLWREDQNEDIQFVMEKGEQVLNLIEKLQFLLLDVPPSEITEKETAQYQETILELENLLHQKYNEATEHLLKSAIMYEDSDTGNMQTVIKDKNVTFCIWANLKKKVRFKNHVFCDTHHGFDLPKSLAVSSIAVRILHTHYDHVSPLWLQCQRVPRLEVLDSQELTQHSQDNAGEPEEEEKEAKEEPNVTAEEETLPDERNSAISFRGNTNSIADTNEVTEEETEKKSENLEVTPEVQIPQMEEKTSEEEEMITDESTVDLQQFVPVGGVYRIDGLQLPPQVQQINSWCVVELLDGGLEAYPYPPQESEDTPHPPIQITLGLPDSVIYWKEPMIARWDPAGKQWRTDGISNITYETQEGNITFEIDAFYTIAFLQDIHLNMPYQAWELRPTSTDEAVFVITAVFAEVQIQIKGNQCMLAAVVVEEKNVLSHLIGKWMCPVTLRRALKKCGLNIFPEEYSYKYVCVNQKAPITEFRAYRQIALVASAFAFGWSKWNLESGQDQVVFKVSEHLKADFVKDEDWSLYMFNGQRAQKLKITEASEAFSMELEEDTEFHSTLYHMLKDFASKEAIDKVNTANFLFVDAVYQLLLATRVLMYS", "length": 712, "header": "tr|A0A8V0YUQ8-1|A0A8V0YUQ8_CHICK Computationally mapped isoform of Dynein axonemal intermediate chain 7 OS=Gallus gallus OX=9031 GN=DNAI7 PE=3 SV=1 CANONICAL=A0A8V0YPQ6-1" }, "locus": { "chromosome": "1", "start_pos": 67257697, "end_pos": 67241429, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034011.1", "url": "https://www.ensembl.org/id/ENSGALT00010034011.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019990.1", "url": "https://www.ensembl.org/id/ENSGALP00010019990.1" } ] } }, { "isoform_ac": "A0A8V0YUR5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPQ6/entry#A0A8V0YUR5-1", "sequence": { "sequence": "MGPKKQKKSGGKNKVGKAEKLRLQKEEEERRLQEEEEARLQAEQEEAARLEKERIERERMKKLEAKDQERREDELAELNSLQEKFVCAQRWKTEYRAYTKWEHYIACDGSPDPTVLQEINTFMNLWREDQNEDIQFVMEKGEQVLNLIEKLQFLLLDVPPSEITEKETAQYQETILELENLLHQKYNEATEHLLKSAIMYEDSDTGNMQTVIKDKNVTFCIWANLKKKVRFKNHVFCDTHHGFDLPKSLAVSSIAVRILHTHYDHVSPLWLQCQRVPRLEVLDSQELTQHSQDNAGEPEEEEKEAKEEPNVTAEEETLPDERNSAISFRGNTNSIADTNEVTEEETEKKSENLEVTPEVQIPQMEEKTSEEEEMITDESTVDLQQFVPVGGVYRIDGLQLPPQVQQINSWCVVELLDGGLEAYPYPPQESEDTPHPPIQITLGLPDSVIYWKEPMIARWDPAGKQWRTDGISNITYETQEGNITFEIDAFYTIAFLQDIHLNMPYQAWELRPTSTDEAVFVITAVFAEVQIQIKGNQCMLAAVVVEEKNVLSHLIGKWMCPVTLRRALKKCGLNIFPEEYSYKYVCVNQKVSEHLKADFVKDEDWSLYMFNGQRAQKLKITEASEAFSMELEEDTEFHSTLYHMLKDFASKEAIDKVNTANFLFVDAVYQLLLATRVLMYS", "length": 681, "header": "tr|A0A8V0YUR5-1|A0A8V0YUR5_CHICK Computationally mapped isoform of Dynein axonemal intermediate chain 7 OS=Gallus gallus OX=9031 GN=DNAI7 PE=3 SV=1 CANONICAL=A0A8V0YPQ6-1" }, "locus": { "chromosome": "1", "start_pos": 67260385, "end_pos": 67241429, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034024.1", "url": "https://www.ensembl.org/id/ENSGALT00010034024.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020000.1", "url": "https://www.ensembl.org/id/ENSGALP00010020000.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A287BQS4-1", "protein_name": "Dynein axonemal intermediate chain 7", "gene_name": "DNAI7", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAGSKKKKITKAERLKQLQEEEERRQKEEEEARVKYAKEEMERLEKQRVEKEKWRKLEAKDLERRNEELEELYLLEGCFPKAEKLKRDDRLLSQWKHYIQCDGSPDPSISQEINTFISLWKEETNETLEAVIAKSKLVLNLIGKLKLILLETPPYDLQEKNIIQYQGSILELQELLHLKFNMATELLLRQASTLADVDSGNMEKVIRDENVTLYVWANLKKNPRYKSVTFSETQVGFEIPRILATSDIALRLLHTHYDHVTPLGPAPAASQEPTSTVTHLVKDEAKGIEAAVSKVLQEESKQQENESNSVHEEETKVEEPGDAEEQKNSVQEEPEVKQHDLEMKLLSETVLAAQLLLLENAQEKPRFFEDDEIDLCQFTTLGGVYHLDILELPPQYKSMKGWMIVEILKEGLQKYVYPPETTEDFETENAFPPIEVMLEVHENVIFFEDPMVARWDAEAKHWKTDGISNVSHKSEERLITFSLETFGPVTLIQDAHVNMPYQSWELRPLDVNKVLLTVTTVFMEIQIQIKENFCMLASIKLNNKKHYSILEEKWMTPISFILALKEAGLNIFPTRHSHFYVATNYKLPLVEIKAYRQMALLSSAFAFGWSKWNAVCDSKKVVFQVREYLPKEEPIQNPNWTLLMFSGDRAQSLRINENSEAFSEALKEETEFHSTLYHMVKDFASKEAMRYIRCSNCQFIDSVCHMLLSTRLLSYS", "length": 716 }, "evidence": [ { "id": "A0A8V0YPQ6", "url": "https://omabrowser.org/oma/group/A0A8V0YPQ6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8I6ACC4-1", "protein_name": "Dynein axonemal intermediate chain 7", "gene_name": "Dnai7", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGPKQKKAPTKKKITKAERLRLLQEEEEKRLKEEEEARLKYEKEEQERLEKQRIEREKWNLLEKKDLERRSEELEELALLECCFPEAEKQKREMRVLAQWKHYTECDGSPDPRIAQEMNTFISLWEEEKNETFEQVMEKSKLVLSLIEKLKLILLETPSCDLDKSTVLQYQGSILRLQELLSLKVNVATELLLRQASNLADLDTGNMEKIIKDENVTLYVWANLKKNPRYRTVKFSQTQVGFEIPRILATSNVALRLLHTHYDHITPLFSTVVTEEKHGSIVAENFKEEERTEKAVPEENVFTEEAADEAEQLKAEEERELSSIPEEEVKFDPTVDTVTQKISDPEEEESQTTQFELERKLLSETVSAAQLSLIENVLEMPETLEPYEVNMCHFAPLGGVYHLEILELPPQSKPVKGWVLAEIRQEGLQKFTYPPENTEEPDPESAFPPIEVTLEIHESAIFFEDPQVVRWDAEGKFWRSDGVTCVYYNRENRLLTFSIDTMGPVTLIQDAHVNMPYQSWELSPLGMNKALLMVTTVFIELQIHIKETHCMLAAVKLKGKSRELRVIGKWMTPIPFILALKEAGLNIFPAVYSHFYVVVNNKVPQMELKAYRQMALLSSAFSFGWSKWNMVREHISEEEEQNTWALLMFSGDRAQMLKMQEESDQFSETLREGSEFHSTLYHMMKDFASPEATEKVRHSNCQFIDSVCYMLLSVRVLSYS", "length": 720 }, "evidence": [ { "id": "A0A8V0YPQ6", "url": "https://omabrowser.org/oma/group/A0A8V0YPQ6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6TDU7-1", "protein_name": "Dynein axonemal intermediate chain 7", "gene_name": "DNAI7", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSGSKKKKVTKAERLKLLQEEEERRLKEEEEARLKYEKEEMERLEIQRIEKEKWHRLEAKDLERRNEELEELYLLERCFPEAEKLKQETKLLSQWKHYIQCDGSPDPSVAQEMNTFISLWKEKTNETFEEVIEKSKVVLNLIEKLKFILLETPPCDLQDKNIIQYQESILQLQELLHLKFGVATEILLKQASTLADLDSGNMEKVIKDENVTLYVWANLKKNPRHRSVRFSETQIGFEIPRILATSDIAVRLLHTHYDHVSALHPVSTPSKEYTSAVTELVKDDVKNVEKAISKEVEEESKQQERGSHLIQEEEIKVEEEQGDIEVKMSSAEEESEAIKCEREMKVLSETVSAAQLLLVENSSEKPDFFEDNVVDLCQFTTLGGVYHLDILELPPQCKPVKGWMIVEILKEGLQKYTYPPETTEEFETENAFPPIEVTLEVHENVIFFEDPVVVRWDAEGKHWRTDGISNVSYKPKERLVTFSLDTFGPVTLIQDAHINMPYQSWELRPLDVNKVLLTVTTVFTEIQIQIKENLCMLSSIKLKDKKHISILEGTWMTPIPFIIALKEAGLNIFPTRHSHFYVIINNKVPLVEVKAYRQMALLSSAFAFGWSKWNLLCNSTKVVFKVREHLTEACTENPNWALLMFSGDRAQRLKIKEESEAFSEALKEETEFHSTLYHMVKDFASEEAMEKVRSSNCQFVNSVCHMLLSTRLLSYS", "length": 716 }, "evidence": [ { "id": "A0A8V0YPQ6", "url": "https://omabrowser.org/oma/group/A0A8V0YPQ6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q6TDU8-1", "protein_name": "Dynein axonemal intermediate chain 7", "gene_name": "Dnai7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAPKSKKAPSKKKMTKAERLRLMQEEEERRLKEEEEARLKFEKEEQERLEIQRIEREKWNLLEKKDLERRSQELEELALLEGCFPEAEKQKREIRALAQWKHYTECDGSPDPWVAQEMNTFISLWEEEKNQAFEQVMEKSKLVLSLIEKVKLILLETPTYELDHRTVLQHQGSILRLQELLSLKINVATELLLRQASNLADLDTGNMEKIIKDENVTLYVWANLKKNPRHRSVRFSETQIGFEIPRILATSNVALRLLHTRYDHITPLFPIAVTEQNQNPVGAEQVNVEESTEKAMTEEKLFTEEKAANEDEQPKAEQERELNLVQEENKYEAIENTVLQRTSDSEGEDSQTTQLELEMKLLSEAVLAAQLCLVENVVELPEASQAYKVDLCHFSTLGGVYHLDVLELPPQCKPVKGWVLVEILQEGLQRFIYPPDTTEEPDPDVTFPPIEVTLEIHKSVIFFERPRVVRWDNEGKFWRSDGISSVYYNREDRLLTFSMDTLGPVTLIQDAHVNMPYQSWEMSPCGMNKVLLIVKTVFMELQIYIKENLCMLASVKLRGKGLEFHLKGKWMAPIPFILALKEAGLNIFPAVYSHFYVVINNKVPQVELKAYRQMALLSSAFSFGWSKWNMVCNSTRVVIRVREQLSEETEHHTWSLLMFSGDRAQMLKMQEENDKFSEALREGTEFHSTLYHMMKDFASPVAMERVRHSNCQFIDSVCYMLLSIRVLSYS", "length": 730 }, "evidence": [ { "id": "A0A8V0YPQ6", "url": "https://omabrowser.org/oma/group/A0A8V0YPQ6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "microtubule binding", "id": "GO:0008017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008017", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPQ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPQ6" } ], "pmid": "" }, { "name": "beta-tubulin binding", "id": "GO:0048487", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048487", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPQ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPQ6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "axoneme", "id": "GO:0005930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005930", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPQ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPQ6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 216, "end_pos": 218, "annotation": "n_glycosylation_sequon" }, { "start_pos": 310, "end_pos": 312, "annotation": "n_glycosylation_sequon" }, { "start_pos": 473, "end_pos": 475, "annotation": "n_glycosylation_sequon" }, { "start_pos": 482, "end_pos": 484, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YPQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPQ6" }, { "id": "PF15927", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15927" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "IC97/Casc1 N-terminal", "eco_id": "ECO_0000259", "start_pos": 30, "end_pos": 230, "start_aa": "Arg", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 216, "end_pos": 218 }, { "start_pos": 310, "end_pos": 312 }, { "start_pos": 473, "end_pos": 475 }, { "start_pos": 482, "end_pos": 484 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YPR0-1", "uniprot_ac": "A0A8V0YPR0", "uniprot_id": "A0A8V0YPR0_CHICK", "mass": { "chemical_mass": 37762.0, "monoisotopic_mass": 37762.0 }, "refseq": {}, "gene_names": [ { "name": "CCDC69", "type": "recommended", "evidence": [ { "id": "A0A8V0YPR0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPR0" } ] } ], "protein_names": [ { "name": "Coiled-coil domain containing 69", "type": "synonym", "evidence": [ { "id": "A0A8V0YPR0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPR0/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPR0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPR0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CCDC69", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPR0", "locus": { "chromosome": "13", "start_pos": 12628574, "end_pos": 12621753, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010014769", "url": "https://www.ensembl.org/id/ENSGALG00010014769" } ] } } ], "crossref": [ { "id": "A0A8V0YPR0", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YPR0", "database": "AlphaFoldDB", "categories": [] }, { "id": "416268", "url": "https://www.ncbi.nlm.nih.gov/gene/416268", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR051293", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051293", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "CLKEVHH", "url": "https://omabrowser.org/oma/group/CLKEVHH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YPQ8", "url": "https://www.orthodb.org/?gene=A0A8V0YPQ8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YPR0", "url": "https://www.orthodb.org/?gene=A0A8V0YPR0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YWG5", "url": "https://www.orthodb.org/?gene=A0A8V0YWG5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24200", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24200", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24200:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24200:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF27558", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF27558", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF27559", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF27559", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YPQ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPQ8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YPQ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPQ8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YPR0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPR0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YPR0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPR0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YWG5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YWG5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YWG5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YWG5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "GGGRAARCWGCRAPSPGAACEQPRRFGTLLINYFPPPPFCLPSWGGSSRPDPSRPLRCRRSAEAAARPSGDDGAPRSPRLRASGLPWAAPAAPCAAAPPAARGSRRASNSRERPARSSAPGGQKTVEEGKDLELKEKFDALRREHEEALQELRRVHEQEKLLLAESHHRSQEALQETIAALKSQLQSFQDRMKRVEESLLSRDYKKHIEEHGSPSPFWEQELESLHFVIEMKNEHIHGLDKKLLNLESVAERNLLLEEKVKTLQQENEDLQVRTQNHLVMTRQLSEELLAIRGALEKESKLREQAHHEKEELLYRVLNGGDGRPFPIAASDVPLIAT", "length": 337, "header": "tr|A0A8V0YPR0-1|A0A8V0YPR0_CHICK Isoform 1 of Coiled-coil domain containing 69 OS=Gallus gallus OX=9031 GN=CCDC69 PE=3 SV=1 CANONICAL=A0A8V0YPR0-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YPQ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPR0/entry#A0A8V0YPQ8-1", "sequence": { "sequence": "MGGSGSALRCCPAGGKVAEPGLPGAGLGRQQKGQQQQGAPSQELSAWRTENANGAGKELAVLGEEHGAEAVKLLQGQEEEERLRGARGAEDEGQRGVSSQVEEGKDLELKEKFDALRREHEEALQELRRVHEQEKLLLAESHHRSQEALQETIAALKSQLQSFQDRMKRVEESLLSRDYKKHIEEHGSPSPFWEQELESLHFVIEMKNEHIHGLDKKLLNLESVAERNLLLEEKVKTLQQENEDLQVRTQNHLVMTRQLSEELLAIRGALEKESKLREQAHHEKEELLYRVLNGGDGRPFPIAASDVPLIAT", "length": 312, "header": "tr|A0A8V0YPQ8-1|A0A8V0YPR0_CHICK Computationally mapped isoform of Coiled-coil domain containing 69 OS=Gallus gallus OX=9031 GN=CCDC69 PE=3 SV=1 CANONICAL=A0A8V0YPR0-1" }, "locus": { "chromosome": "13", "start_pos": 12627792, "end_pos": 12622047, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010035503.1", "url": "https://www.ensembl.org/id/ENSGALT00010035503.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020638.1", "url": "https://www.ensembl.org/id/ENSGALP00010020638.1" } ] } }, { "isoform_ac": "A0A8V0YPR0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPR0/entry#A0A8V0YPR0-1", "sequence": { "sequence": "GGGRAARCWGCRAPSPGAACEQPRRFGTLLINYFPPPPFCLPSWGGSSRPDPSRPLRCRRSAEAAARPSGDDGAPRSPRLRASGLPWAAPAAPCAAAPPAARGSRRASNSRERPARSSAPGGQKTVEEGKDLELKEKFDALRREHEEALQELRRVHEQEKLLLAESHHRSQEALQETIAALKSQLQSFQDRMKRVEESLLSRDYKKHIEEHGSPSPFWEQELESLHFVIEMKNEHIHGLDKKLLNLESVAERNLLLEEKVKTLQQENEDLQVRTQNHLVMTRQLSEELLAIRGALEKESKLREQAHHEKEELLYRVLNGGDGRPFPIAASDVPLIAT", "length": 337, "header": "tr|A0A8V0YPR0-1|A0A8V0YPR0_CHICK Isoform 1 of Coiled-coil domain containing 69 OS=Gallus gallus OX=9031 GN=CCDC69 PE=3 SV=1 CANONICAL=A0A8V0YPR0-1" }, "locus": { "chromosome": "13", "start_pos": 12627792, "end_pos": 12621790, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010035498.1", "url": "https://www.ensembl.org/id/ENSGALT00010035498.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020636.1", "url": "https://www.ensembl.org/id/ENSGALP00010020636.1" } ] } }, { "isoform_ac": "A0A8V0YWG5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPR0/entry#A0A8V0YWG5-1", "sequence": { "sequence": "KGRCSRGFPEAQHSQLSGSTLPCSCKRRAAGEQSSTAPVCFALLFSPARLPNARQQKGQQQQGAPSQELSAWRTENANGAGKELAVLGEEHGAEAVKLLQGQEEEERLRGARGAEDEGQRGVSSQVEEGKDLELKEKFDALRREHEEALQELRRVHEQEKLLLAESHHRSQEALQETIAALKSQLQSFQDRMKRVEESLLSRDYKKHIEEHGSPSPFWEQELESLHFVIEMKNEHIHGLDKKLLNLESVAERNLLLEEKVKTLQQENEDLQVRTQNHLVMTRQLSEELLAIRGALEKESKLREQAHHEKEELLYRVLNGGDGRPFPIAASDVPLIAT", "length": 337, "header": "tr|A0A8V0YWG5-1|A0A8V0YWG5_CHICK Computationally mapped isoform of Coiled-coil domain containing 69 OS=Gallus gallus OX=9031 GN=CCDC69 PE=3 SV=1 CANONICAL=A0A8V0YPR0-1" }, "locus": { "chromosome": "13", "start_pos": 12627792, "end_pos": 12625130, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010035491.1", "url": "https://www.ensembl.org/id/ENSGALT00010035491.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020635.1", "url": "https://www.ensembl.org/id/ENSGALP00010020635.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "spindle", "id": "GO:0005819", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005819", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPR0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPR0" } ], "pmid": "" }, { "name": "midbody", "id": "GO:0030496", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030496", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPR0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPR0" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPR0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPR0" } ], "pmid": "" }, { "name": "spindle midzone", "id": "GO:0051233", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051233", "evidence": [ { "database": "UniProtKB", "id": 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This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_025011161.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_025011161", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025011161" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPR1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPR1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CDC42EP1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPR1", "locus": { "chromosome": "1", "start_pos": 51260205, "end_pos": 51266476, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010014159", "url": "https://www.ensembl.org/id/ENSGALG00010014159" } ] } } ], "crossref": [ { "id": "A0A8V0YPR1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YPR1", "database": "AlphaFoldDB", "categories": [] }, { "id": "418040", 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"n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YPR9-1", "uniprot_ac": "A0A8V0YPR9", "uniprot_id": "A0A8V0YPR9_CHICK", "mass": { "chemical_mass": 78546.0, "monoisotopic_mass": 78546.0 }, "refseq": {}, "gene_names": [ { "name": "MCCC1", "type": "recommended", "evidence": [ { "id": "A0A8V0YPR9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPR9" } ] } ], "protein_names": [ { "name": "Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial", "type": "recommended", "evidence": [ { "id": "A0A8V0YPR9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPR9/entry#names_and_taxonomy" } ] }, { "name": "3-methylcrotonyl-CoA carboxylase 1", "type": "synonym", "evidence": [ { "id": "A0A8V0YPR9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPR9/entry#names_and_taxonomy" } ] }, { "name": "3-methylcrotonyl-CoA carboxylase biotin-containing subunit", "type": "synonym", "evidence": [ { "id": "A0A8V0YPR9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPR9/entry#names_and_taxonomy" } ] }, { "name": "3-methylcrotonyl-CoA:carbon dioxide ligase subunit alpha", "type": "synonym", "evidence": [ { "id": "A0A8V0YPR9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPR9/entry#names_and_taxonomy" } ] }, { "name": "6.4.1.4", "type": "synonym", "evidence": [ { "id": "A0A8V0YPR9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPR9/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Biotin-attachment subunit of the 3-methylcrotonyl-CoA carboxylase, an enzyme that catalyzes the conversion of 3-methylcrotonyl-CoA to 3-methylglutaconyl-CoA, a critical step for leucine and isovaleric acid catabolism.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPR9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPR9#function" }, { "database": "UniProtKB", "id": "ARBA00055202", "url": "https://www.uniprot.org/uniprotkb/ARBA00055202#function" }, { "database": "UniProtKB", "id": "A0A8V0Z302", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z302#function" }, { "database": "UniProtKB", "id": "A0A8V0YPR2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPR2#function" }, { "database": "UniProtKB", "id": "A0A8V0YWJ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YWJ5#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPR9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPR9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MCCC1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPR9", "locus": { "chromosome": "9", "start_pos": 16108808, "end_pos": 16091147, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010016475", "url": "https://www.ensembl.org/id/ENSGALG00010016475" } ] } } ], "crossref": [ { "id": "A0A8V0YPR9", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YPR9", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd06850", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06850", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000089", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000089", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001882", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001882", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005479", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005479", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005481", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005481", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005482", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005482", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011053", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011053", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011054", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011054", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011761", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011761", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011764", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011764", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013815", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013815", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016185", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016185", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050856", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050856", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YPR2", "url": "https://www.orthodb.org/?gene=A0A8V0YPR2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YPR9", "url": "https://www.orthodb.org/?gene=A0A8V0YPR9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YWJ5", "url": "https://www.orthodb.org/?gene=A0A8V0YWJ5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YWK5", "url": "https://www.orthodb.org/?gene=A0A8V0YWK5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z302", "url": "https://www.orthodb.org/?gene=A0A8V0Z302", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR18866", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR18866", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR18866:SF33", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR18866:SF33", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00289", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00289", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00364", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00364", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02785", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02785", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02786", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02786", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-196780", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-196780", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-70895", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-70895", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "13589", "url": "https://www.rhea-db.org/rhea/13589", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YPR2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPR2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YPR2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPR2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YPR9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPR9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YPR9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPR9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YWJ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YWJ5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YWJ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YWJ5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YWK5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YWK5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YWK5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YWK5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z302", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z302", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z302-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z302-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MALVLVAERGRYCLRALQRQPWSPVQLLAKCASTAEGHSIGKILIANRGEIACRVMRTARKMGVKSVAVYSEADRNSMHVAMADEAYCIGPAPSQQSYLAVEKIIQVAKTSAAQAIHPGYGFLSENTEFAELCKQEGIIFIGPPSSAIRDMGIKSTSKAIMSAAGVPVVEGYHGEDQSDQCLKEHAMRIGYPVMIKAVRGGGGKGMRIAHSEKEFLDQLESARREAKKSFNDDAMLIEKFVDNPRHVEVQVFGDQHGNAVYLFERDCSVQRRHQKIIEEAPGPGINPEVRKRLGEAAVKAAKAVNYVGAGTVEFIMDSQHNFYFMEMNTRLQVEHPVTEMITGTDLVEWQLRVAAGENIPLMQEEILLRGHAFEARIYAEDPTNNFLPGAGPLVHLSTPPPDRDTRIETGVRQGDEVSVHYDPMIAKLVVWAEDREAALRKLRYSLHQYNIVGLSTNIDFLLSLSGHPQFEAGNVHTNFIPQYHDDLFPAKKATPLEVVCQAALGLILKEKMLSDAYRDQSSDKFSPFAFSTGRRINILYTRKLSLLDGENIVDVAVTYNREGSYNMQIQDRMFLVSGEIFNEGDSVYLRSSVNGAVCKSKLVILDNIIHLFSPEGSAQIGLPVPKYLSAVSSAGTQGGAVAPMTGTVEKVFVKAGDKVEIGDPLMVMIAMKMEHTIRAPKAGVIKKVNFQEGAQANRHAPLVEFMDEAAESK", "length": 713, "header": "tr|A0A8V0YPR9-1|A0A8V0YPR9_CHICK Isoform 1 of Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial OS=Gallus gallus OX=9031 GN=MCCC1 PE=1 SV=1 CANONICAL=A0A8V0YPR9-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YPR2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPR9/entry#A0A8V0YPR2-1", "sequence": { "sequence": "MALVLVAERGRYCLRALQRQPWSPVQLLAKCASTAEGHSIGKILIANRGEIACRVMRTARKMDEAYCIGPAPSQQSYLAVEKIIQVAKTSAAQAIHPGYGFLSENTEFAELCKQEGIIFIGPPSSAIRDMGIKSTSKAIMSAAGVPVVEGYHGEDQSDQCLKEHAMRIGYPVMIKAVRGGGGKGMRIAHSEKEFLDQLESARREAKKSFNDDAMLIEKFVDNPRHVEVQVFGDQHGNAVYLFERDCSVQRRHQKIIEEAPGPGINPEVRKRLGEAAVKAAKAVNYVGAGTVEFIMDSQHNFYFMEMNTRLQVEHPVTEMITGTDLVEWQLRVAAGENIPLMQEEILLRGHAFEARIYAEDPTNNFLPGAGPLVHLSTPPPDRDTRIETGVRQGDEVSVHYDPMIAKLVVWAEDREAALRKLRYSLHQYNIVGLSTNIDFLLSLSGHPQFEAGNVHTNFIPQYHDDLFPAKKATPLEVVCQAALGLILKEKMLSDAYRDQSSDKFSPFAFSTGRRINILYTRKLSLLDGENIVDVAVTYNREGSYNMQIQDRMFLVSGEIFNEGDSVYLRSSVNGAVCKSKLVILDNIIHLFSPEGSAQIGLPVPKYLSAVSSAGTQGGAVAPMTGTVEKVFVKAGDKVEIGDPLMVMIAMKMEHTIRAPKAGVIKKVNFQEGAQANRHAPLVEFMDEAAESK", "length": 692, "header": "tr|A0A8V0YPR2-1|A0A8V0YPR9_CHICK Computationally mapped isoform of Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial OS=Gallus gallus OX=9031 GN=MCCC1 PE=1 SV=1 CANONICAL=A0A8V0YPR9-1" }, "locus": { "chromosome": "9", "start_pos": 16105544, "end_pos": 16091163, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010039747.1", "url": "https://www.ensembl.org/id/ENSGALT00010039747.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010022997.1", "url": "https://www.ensembl.org/id/ENSGALP00010022997.1" } ] } }, { "isoform_ac": "A0A8V0YPR9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPR9/entry#A0A8V0YPR9-1", "sequence": { "sequence": "MALVLVAERGRYCLRALQRQPWSPVQLLAKCASTAEGHSIGKILIANRGEIACRVMRTARKMGVKSVAVYSEADRNSMHVAMADEAYCIGPAPSQQSYLAVEKIIQVAKTSAAQAIHPGYGFLSENTEFAELCKQEGIIFIGPPSSAIRDMGIKSTSKAIMSAAGVPVVEGYHGEDQSDQCLKEHAMRIGYPVMIKAVRGGGGKGMRIAHSEKEFLDQLESARREAKKSFNDDAMLIEKFVDNPRHVEVQVFGDQHGNAVYLFERDCSVQRRHQKIIEEAPGPGINPEVRKRLGEAAVKAAKAVNYVGAGTVEFIMDSQHNFYFMEMNTRLQVEHPVTEMITGTDLVEWQLRVAAGENIPLMQEEILLRGHAFEARIYAEDPTNNFLPGAGPLVHLSTPPPDRDTRIETGVRQGDEVSVHYDPMIAKLVVWAEDREAALRKLRYSLHQYNIVGLSTNIDFLLSLSGHPQFEAGNVHTNFIPQYHDDLFPAKKATPLEVVCQAALGLILKEKMLSDAYRDQSSDKFSPFAFSTGRRINILYTRKLSLLDGENIVDVAVTYNREGSYNMQIQDRMFLVSGEIFNEGDSVYLRSSVNGAVCKSKLVILDNIIHLFSPEGSAQIGLPVPKYLSAVSSAGTQGGAVAPMTGTVEKVFVKAGDKVEIGDPLMVMIAMKMEHTIRAPKAGVIKKVNFQEGAQANRHAPLVEFMDEAAESK", "length": 713, "header": "tr|A0A8V0YPR9-1|A0A8V0YPR9_CHICK Isoform 1 of Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial OS=Gallus gallus OX=9031 GN=MCCC1 PE=1 SV=1 CANONICAL=A0A8V0YPR9-1" }, "locus": { "chromosome": "9", "start_pos": 16105544, "end_pos": 16091163, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010039761.1", "url": "https://www.ensembl.org/id/ENSGALT00010039761.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023007.1", "url": "https://www.ensembl.org/id/ENSGALP00010023007.1" } ] } }, { "isoform_ac": "A0A8V0YWJ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPR9/entry#A0A8V0YWJ5-1", "sequence": { "sequence": "MALVLVAERGRYCLRALQRHIFHFKIGHSIGKILIANRGEIACRVMRTARKMGVKSVAVYSEADRNSMHVAMADEAYCIGPAPSQQSYLAVEKIIQVAKTSAAQAIHPGYGFLSENTEFAELCKQEGIIFIGPPSSAIRDMGIKSTSKAIMSAAGVPVVEGYHGEDQSDQCLKEHAMRIGYPVMIKAVRGGGGKGMRIAHSEKEFLDQLESARREAKKSFNDDAMLIEKFVDNPRHVEVQVFGDQHGNAVYLFERDCSVQRRHQKIIEEAPGPGINPEVRKRLGEAAVKAAKAVNYVGAGTVEFIMDSQHNFYFMEMNTRLQVEHPVTEMITGTDLVEWQLRVAAGENIPLMQEEILLRGHAFEARIYAEDPTNNFLPGAGPLVHLSTPPPDRDTRIETGVRQGDEVSVHYDPMIAKLVVWAEDREAALRKLRYSLHQYNIVGLSTNIDFLLSLSGHPQFEAGNVHTNFIPQYHDDLFPAKKATPLEVVCQAALGLILKEKMLSDAYRDQSSDKFSPFAFSTGRRINILYTRKLSLLDGENIVDVAVTYNREGSYNMQIQDRMFLVSGEIFNEGDSVYLRSSVNGAVCKSKLVILDNIIHLFSPEGSAQIGLPVPKYLSAVSSAGTQGGAVAPMTGTVEKVFVKAGDKVEIGDPLMVMIAMKMEHTIRAPKAGVIKKVNFQEGAQANRHAPLVEFMDEAAESK", "length": 703, "header": "tr|A0A8V0YWJ5-1|A0A8V0YWJ5_CHICK Computationally mapped isoform of Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial OS=Gallus gallus OX=9031 GN=MCCC1 PE=1 SV=1 CANONICAL=A0A8V0YPR9-1" }, "locus": { "chromosome": "9", "start_pos": 16105544, "end_pos": 16091163, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010039753.1", "url": "https://www.ensembl.org/id/ENSGALT00010039753.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023001.1", "url": "https://www.ensembl.org/id/ENSGALP00010023001.1" } ] } }, { "isoform_ac": "A0A8V0YWK5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPR9/entry#A0A8V0YWK5-1", "sequence": { "sequence": "MALVLVAERGRYCLRALQRQPWSPVQLLAKCASTAEGHSIGKILIANRGEIACRVMRTARKMGVKSVAVYSEADRNSMHVAMADEAYCIGPAPSQQSYLAVEKIIQVAKTSAAQAIHPGYGFLSENTEFAELCKQEGIIFIGPPSSAIRDMGIKSTSKAIMSAAGVPVVEGYHGEDQSDQCLKEHAMRIGYPVMIKAVRGGGGKGMRIAHSEKEFLDQLESARREAKKSFNDDAMLIEKFVDNPRHVEVQVFGDQHGNAVYLFERDCSVQRRHQKIIEEAPGPGINPEVRKRLGEAAVKAAKAVNYVGAGTVEFIMDSQHNFYFMEMNTRLQVEHPVTEMITGTDLVEWQLRVAAGENIPLMQEEILLRGHAFEARIYAEDPTNNFLPGAGPLVHLSTPPPDRDTRIETGVRQGDEVSVHYDPMIAKLVVWAEDREAALRKLRYSLHQYNIVGLSTNIDFLLSLSGHPQFEAGNVHTNFIPQYHDDLFPAKKATPLEVVCQAALGLILKEKMLSDAYRDQSSDKFSPFAFSTGRRINILYTRKLSLLDGENIVDVAVTYNREGSYNMQIQDRMFLVSGEIFNEGDSVYLRSSVNGAVCKSKLVILDNIIHLFSPVFVKAGDKVEIGDPLMVMIAMKMEHTIRAPKAGVIKKVNFQEGAQANRHAPLVEFMDEAAESK", "length": 677, "header": "tr|A0A8V0YWK5-1|A0A8V0YWK5_CHICK Computationally mapped isoform of Methylcrotonoyl-CoA carboxylase 1 OS=Gallus gallus OX=9031 GN=MCCC1 PE=1 SV=1 CANONICAL=A0A8V0YPR9-1" }, "locus": { "chromosome": "9", "start_pos": 16105544, "end_pos": 16091163, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010039766.1", "url": "https://www.ensembl.org/id/ENSGALT00010039766.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023011.1", "url": "https://www.ensembl.org/id/ENSGALP00010023011.1" } ] } }, { "isoform_ac": "A0A8V0Z302-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPR9/entry#A0A8V0Z302-1", "sequence": { "sequence": "MALVLVAERGRYCLRALQRQPWSPVQLLAKCASTAEGHSIGKILIANRGEIACRVMRTARKMGVKSVAVYSEADRNSMHVAMADEAYCIGPAPSQQSYLAVEKIIQVAKTSAAQAIHPGYGFLSENTEFAELCKQEGIIFIGPPSSAIRDMGIKSTSKAIMSAAGVPVVEGYHGEDQSDQCLKEHAMRIGYPVMIKAVRGGGGKGMRIAHSEKEFLDQLESARREAKKSFNDDAMLIEKFVDNPRHVEVQVFGDQHGNAVYLFERDCSVQRRHQKIIEEAPGPGINPEVRKRLGEAAVKAAKAVNYVGAGTVEFIMDSQHNFYFMEMNTRLQVEHPVTEMITGTDLVEWQLRVAAGENIPLMQEEILLRGHAFEARIYAEDPTNNFLPGAGPLVHLSTPPPDRDTRIETGVRQGDEVSVHYDPMIAKLVVWAEDREAALRKLRYSLHQYNIVGLSTNIDFLLSLSGHPQFEAGNVHTNFIPQYHDDLFPAKKATPLEVVCQAALGLILKEKMLSDAYRDQSSDKFSPFIQDRMFLVSGEIFNEGDSVYLRSSVNGAVCKSKLVILDNIIHLFSPEGSAQIGLPVPKYLSAVSSAGTQGGAVAPMTGTVEKVFVKAGDKVEIGDPLMVMIAMKMEHTIRAPKAGVIKKVNFQEGAQANRHAPLVEFMDEAAESK", "length": 673, "header": "tr|A0A8V0Z302-1|A0A8V0Z302_CHICK Computationally mapped isoform of Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial OS=Gallus gallus OX=9031 GN=MCCC1 PE=1 SV=1 CANONICAL=A0A8V0YPR9-1" }, "locus": { "chromosome": "9", "start_pos": 16105544, "end_pos": 16091163, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010039733.1", "url": "https://www.ensembl.org/id/ENSGALT00010039733.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010022987.1", "url": "https://www.ensembl.org/id/ENSGALP00010022987.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "R-GGA-196780", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-196780", "resource": "Reactome", "description": "Biotin transport and metabolism" }, { "id": "R-GGA-70895", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-70895", "resource": "Reactome", "description": "Branched-chain amino acid catabolism" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPR9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPR9" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPR9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPR9" } ], "pmid": "" }, { "name": "methylcrotonoyl-CoA carboxylase activity", "id": "GO:0004485", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004485", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPR9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPR9" } ], "pmid": "" }, { "name": "ligase activity", "id": "GO:0016874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016874", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPR9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPR9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "mitochondrial matrix", "id": "GO:0005759", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005759", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPR9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPR9" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPR9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPR9" } ], "pmid": "" }, { "name": "methylcrotonoyl-CoA carboxylase complex", "id": "GO:1905202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905202", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPR9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPR9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "13589", "name": "", "equation": "3-methylbut-2-enoyl-CoA + hydrogencarbonate + ATP = 3-methyl-(2E)-glutaconyl-CoA + ADP + phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1P531-1", "A0A8V0ZWN0-1", "A0A8V0YPR9-1" ], "evidence": [ { "id": "13589", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/13589" } ] }, { "id": "R-GGA-2993799", "name": "HLCS biotinylates 6xMCCC1:6xMCCC2", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YPR9-1", "F1P531-1" ], "evidence": [ { "id": "R-GGA-2993799", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2993799" } ] }, { "id": "R-GGA-3323111", "name": "Cytosolic carboxylases translocate to mitochondrial matrix", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, mitochondrial matrix", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XS41-1", "A0A8V0YPR9-1", "A0A8V0ZX51-1", "F1P531-1" ], "evidence": [ { "id": "R-GGA-3323111", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3323111" } ] }, { "id": "R-GGA-508308", "name": "beta-methylglutaconyl-CoA + ADP + orthophosphate <=> beta-methylcrotonyl-CoA + ATP + HCO3- (MCCA)", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "mitochondrial matrix", "input_participant_list": [ "R-ALL-113548", "R-ALL-70772" ], "output_participant_list": [ "R-ALL-29896", "R-ALL-70744" ], "enzyme_list": [ "A0A8V0YPR9-1", "F1P531-1" ], "evidence": [ { "id": "R-GGA-508308", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-508308" } ] }, { "id": "R-GGA-70773", "name": "beta-methylcrotonyl-CoA + ATP + HCO3- <=> beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O (MCCA)", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "mitochondrial matrix", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YPR9-1", "F1P531-1" ], "evidence": [ { "id": "R-GGA-70773", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-70773" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-113548", "participant_name": "Pi [mitochondrial matrix]", "crossref": [ { "id": "43474", "database": "ChEBI", "url": "" }, { "id": "C00009", "database": "COMPOUND", "url": "" } ] }, { "participant_id": "R-ALL-29896", "participant_name": "HCO3- [mitochondrial matrix]", "crossref": [ { "id": "17544", "database": "ChEBI", "url": "" }, { "id": "C00288", "database": "COMPOUND", "url": "" }, { "id": "ZINC000006827693", "database": "ZINC", "url": "" }, { "id": "11533114", "database": "PubChem Substance", "url": "" } ] }, { "participant_id": "R-ALL-70744", "participant_name": "bMC-CoA [mitochondrial matrix]", "crossref": [ { "id": "C03069", "database": "COMPOUND", "url": "" }, { "id": "57344", "database": "ChEBI", "url": "" }, { "id": "ZINC000008551513", "database": "ZINC", "url": "" } ] }, { "participant_id": "R-ALL-70772", "participant_name": "bMG-CoA [mitochondrial matrix]", "crossref": [ { "id": "57346", "database": "ChEBI", "url": "" }, { "id": "ZINC000096077648", "database": "ZINC", "url": "" }, { "id": "C03231", "database": "COMPOUND", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A0A8V0XS41", "gene_name": "PCCA", "activity": [ { "ec_number": "6.4.1.3", "activity": "propanoyl-CoA + hydrogencarbonate + ATP = (S)-methylmalonyl-CoA + ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XS41", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XS41" } ] }, { "ec_number": "6.4.1.3", "activity": "", "evidence": [ { "id": "A0A8V0XS41", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XS41" } ] } ] }, { "uniprot_ac": "A0A8V0YPR9", "gene_name": "MCCC1", "activity": [ { "ec_number": "6.4.1.4", "activity": "3-methylbut-2-enoyl-CoA + hydrogencarbonate + ATP = 3-methyl-(2E)-glutaconyl-CoA + ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YPR9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPR9" } ] }, { "ec_number": "6.4.1.4", "activity": "", "evidence": [ { "id": "A0A8V0YPR9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPR9" } ] } ] }, { "uniprot_ac": "A0A8V0ZWN0", "gene_name": "MCCC2L", "activity": [ { "ec_number": "6.4.1.4", "activity": "3-methylbut-2-enoyl-CoA + hydrogencarbonate + ATP = 3-methyl-(2E)-glutaconyl-CoA + ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0ZWN0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWN0" } ] }, { "ec_number": "6.4.1.4", "activity": "", "evidence": [ { "id": "A0A8V0ZWN0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWN0" } ] } ] }, { "uniprot_ac": "A0A8V0ZX51", "gene_name": "PCCB", "activity": [ { "ec_number": "6.4.1.3", "activity": "propanoyl-CoA + hydrogencarbonate + ATP = (S)-methylmalonyl-CoA + ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0ZX51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZX51" } ] }, { "ec_number": "6.4.1.3", "activity": "", "evidence": [ { "id": "A0A8V0ZX51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZX51" } ] } ] }, { "uniprot_ac": "F1P531", "gene_name": "MCCC2", "activity": [ { "ec_number": "6.4.1.4", "activity": "3-methylbut-2-enoyl-CoA + hydrogencarbonate + ATP = 3-methyl-(2E)-glutaconyl-CoA + ADP + phosphate + H(+).", "evidence": [ { "id": "F1P531", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P531" } ] }, { "ec_number": "6.4.1.4", "activity": "", "evidence": [ { "id": "F1P531", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P531" } ] } ] } ], "biomarkers": [], 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}, { "id": "PS50968", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50968" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Lipoyl-binding", "eco_id": "ECO_0000259", "start_pos": 617, "end_pos": 706, "start_aa": "Ser", "end_aa": "Met", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "6.4.1.4", "ec_name": "3-methylbut-2-enoyl-CoA + hydrogencarbonate + ATP = 3-methyl-(2E)-glutaconyl-CoA + ADP + phosphate + H(+).", "evidence": [ { "id": "6.4.1.4", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:6.4.1.4" }, { "id": "6.4.1.4", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=6.4.1.4" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, 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"glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YPS1-1", "uniprot_ac": "A0A8V0YPS1", "uniprot_id": "A0A8V0YPS1_CHICK", "mass": { "chemical_mass": 123508.0, "monoisotopic_mass": 123508.0 }, "refseq": { "ac": "XP_015153070", "name": "leucine zipper protein 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015153070" }, "gene_names": [ { "name": "LUZP1", "type": "recommended", "evidence": [ { "id": "A0A8V0YPS1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPS1" } ] }, { "name": "LUZP1", "type": "synonym", "evidence": [ { "id": "XP_015153070", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015153070" } ] } ], "protein_names": [ { "name": "Leucine zipper protein 1", "type": "synonym", "evidence": [ { "id": "A0A8V0YPS1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPS1/entry#names_and_taxonomy" } ] }, { "name": "leucine zipper protein 1", "type": "synonym", "evidence": [ { "id": "XP_015153070", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015153070" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052554.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015153070.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015153070", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015153070" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPS1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPS1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LUZP1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPS1", "locus": { "chromosome": "23", "start_pos": 2061258, "end_pos": 2030253, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010014165", "url": "https://www.ensembl.org/id/ENSGALG00010014165" } ] } } ], "crossref": [ { "id": "A0A8V0YPS1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YPS1", "database": "AlphaFoldDB", "categories": [] }, { "id": "428210", "url": "https://www.ncbi.nlm.nih.gov/gene/428210", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR050719", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050719", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:428210", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:428210", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "NVKKIMG", "url": "https://omabrowser.org/oma/group/NVKKIMG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YPS1", "url": "https://www.orthodb.org/?gene=A0A8V0YPS1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YUS4", "url": "https://www.orthodb.org/?gene=A0A8V0YUS4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23166", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23166", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23166:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23166:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "XP_015153070", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015153070", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YPS1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPS1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YPS1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPS1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YUS4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUS4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YUS4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUS4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAEFTGYKETSNRHLRFKLQSLSRRLDELEEATKNLQKAEDELLELQDKVIQAEGSNSSMLADIEALRKRVLKIEGKDEEIKKAEELCRLMKEKLEEEESLTRELKSEIEHLQKRMAELEKLEEAFGRSKNDCTQLCLSLNEERNLTKKISTELEILRVKVKELEASEERMDKTEQSLTGELEKLKSLALSFISERKHFNEREKQNEKIIQELTLKLEQNNKLNRADQTRNASNLLERSSNNLLDRNDLRIEDDLTSALPSKETRRKGSVDYLKHVENETRNKSENQKNKNQEDNKVKDLTQEIERLKTQIKRFESLEEELKKMRAKNNDLQDSYLSEQNKNKLLTGELEEIKMQIKKQKDLENGEVENEDTSFSGRGKHDRAKYRVVAADFTAAKHKPREVSPQQRRERVRNRDFSFSNDSSSHGGKQTPSPSLMSRKAGKTSGAAALADAAATDTKKLEEKCLVSTFSSGQKEASFTQNEGKRPKEQPSVLSRYPPAAHEQKSWKTPSKPVSDLRSKAEKPSQATRGSCQSGADTRDEKSSRGESVASLAEKLKTNQGEVSDAVGDTQQSRGHCASANGVATAYRCHISPAESDPVGSKAEAGNASTASHRQPLEGRTKRAVISQEKELIDVSLESVKASPLTKRSHRSRSQEDILQILKEDAEQSAAAGHVNASLKAGSKTVQSSHEKLNSDEEAGRSKKANTQSDFETRKKANSKQFSNSRGVFRASLFENDKSTAHDEDSSKCIKPSDADTGGLKSRRSFSPREALRSKAIIKPAIVEKDMKAIMGGAVTETESEKQKSVIKAVTNKMTSSITIFPSEPTVPRPSTDTAGKERHITTSNIRVAPNEPSPITNSLPQPFEVSVNRSALKLSETDRSGDAVLRSRTETVVSRSSIVIKTSEPPERSGELPLDTASSRSHGSPDSISSETKHVTLRSSWRTRQGLPSLEDSQIKVEKNAASSPTNACRSSVDLSEMEGSSTRTNSLEQSSARSGATTNSWSAPEMGSRRTKSNLSASELLTRRSYTSDPTTASPWHRTTLPDESKDFVSSSRRKQYGSSEYLSQADTAGRRAVPPPEQLQDPTSNPNSPPGLQAEDQGASRVGRPTSRR", "length": 1111, "header": "tr|A0A8V0YPS1-1|A0A8V0YPS1_CHICK Isoform 1 of Leucine zipper protein 1 OS=Gallus gallus OX=9031 GN=LUZP1 PE=1 SV=1 CANONICAL=A0A8V0YPS1-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YPS1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPS1/entry#A0A8V0YPS1-1", "sequence": { "sequence": "MAEFTGYKETSNRHLRFKLQSLSRRLDELEEATKNLQKAEDELLELQDKVIQAEGSNSSMLADIEALRKRVLKIEGKDEEIKKAEELCRLMKEKLEEEESLTRELKSEIEHLQKRMAELEKLEEAFGRSKNDCTQLCLSLNEERNLTKKISTELEILRVKVKELEASEERMDKTEQSLTGELEKLKSLALSFISERKHFNEREKQNEKIIQELTLKLEQNNKLNRADQTRNASNLLERSSNNLLDRNDLRIEDDLTSALPSKETRRKGSVDYLKHVENETRNKSENQKNKNQEDNKVKDLTQEIERLKTQIKRFESLEEELKKMRAKNNDLQDSYLSEQNKNKLLTGELEEIKMQIKKQKDLENGEVENEDTSFSGRGKHDRAKYRVVAADFTAAKHKPREVSPQQRRERVRNRDFSFSNDSSSHGGKQTPSPSLMSRKAGKTSGAAALADAAATDTKKLEEKCLVSTFSSGQKEASFTQNEGKRPKEQPSVLSRYPPAAHEQKSWKTPSKPVSDLRSKAEKPSQATRGSCQSGADTRDEKSSRGESVASLAEKLKTNQGEVSDAVGDTQQSRGHCASANGVATAYRCHISPAESDPVGSKAEAGNASTASHRQPLEGRTKRAVISQEKELIDVSLESVKASPLTKRSHRSRSQEDILQILKEDAEQSAAAGHVNASLKAGSKTVQSSHEKLNSDEEAGRSKKANTQSDFETRKKANSKQFSNSRGVFRASLFENDKSTAHDEDSSKCIKPSDADTGGLKSRRSFSPREALRSKAIIKPAIVEKDMKAIMGGAVTETESEKQKSVIKAVTNKMTSSITIFPSEPTVPRPSTDTAGKERHITTSNIRVAPNEPSPITNSLPQPFEVSVNRSALKLSETDRSGDAVLRSRTETVVSRSSIVIKTSEPPERSGELPLDTASSRSHGSPDSISSETKHVTLRSSWRTRQGLPSLEDSQIKVEKNAASSPTNACRSSVDLSEMEGSSTRTNSLEQSSARSGATTNSWSAPEMGSRRTKSNLSASELLTRRSYTSDPTTASPWHRTTLPDESKDFVSSSRRKQYGSSEYLSQADTAGRRAVPPPEQLQDPTSNPNSPPGLQAEDQGASRVGRPTSRR", "length": 1111, "header": "tr|A0A8V0YPS1-1|A0A8V0YPS1_CHICK Isoform 1 of Leucine zipper protein 1 OS=Gallus gallus OX=9031 GN=LUZP1 PE=1 SV=1 CANONICAL=A0A8V0YPS1-1" }, "locus": { "chromosome": "23", "start_pos": 2058548, "end_pos": 2051243, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034049.1", "url": "https://www.ensembl.org/id/ENSGALT00010034049.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020012.1", "url": "https://www.ensembl.org/id/ENSGALP00010020012.1" } ] } }, { "isoform_ac": "A0A8V0YUS4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPS1/entry#A0A8V0YUS4-1", "sequence": { "sequence": "MAEFTGYKETSNRHLRFKLQSLSRRLDELEEATKNLQKAEDELLELQDKVIQAEGSNSSMLADIEALRKRVLKIEGKDEEIKKAEELCRLMKEKLEEEESLTRELKSEIEHLQKRMAELEKLEEAFGRSKNDCTQLCLSLNEERNLTKKISTELEILRVKVKELEASEERMDKTEQSLTGELEKLKSLALSFISERKHFNEREKQNEKIIQELTLKLEQNNKLNRADQTRNASNLLERSSNNLLDRNDLRIEDDLTSALPSKETRRKGSVDYLKHVENETRNKSENQKNKNQEDNKVKDLTQEIERLKTQIKRFESLEEELKKMRAKNNDLQDSYLSEQNKNKLLTGELEEIKMQIKKQKDLENGEVENEDTSFSGRGKHDRAKYRVVAADFTAAKHKPREVSPQQRRERVRNRDFSFSNDSSSHGGKQTPSPSLMSRKAGKTSGAAALADAAATDTKKLEEKCLVSTFSSGQKEASFTQNEGKRPKEQPSVLSRYPPAAHEQKSWKTPSKPVSDLRSKAEKPSQATRGSCQSGADTRDEKSSRGESVASLAEKLKTNQGEVSDAVGDTQQSRGHCASANGVATAYRCHISPAESDPVGSKAEAGNASTASHRQPLEGRTKRAVISQEKELIDVSLESVKASPLTKRSHRSRSQEDILQILKEDAEQSAAAGHVNASLKAGSKTVQSSHEKLNSDEEAGRSKKANTQSDFETRKKANSKQFSNSRGVFRASLFENDKSTAHDEDSSKCIKPSDADTGGLKSRRSFSPREALRSKAIIKPAIVEKDMKAIMGGAVTETESEKQKSVIKAVTNKMTSSITIFPSEPTVPRPSTDTAGKERHITTSNIRVAPNEPSPITNSLPQPFEVSVNRSALKLSETDRSGDAVLRSRTETVVSRSSIVIKTSEPPERSGELPLDTASSRSHGSPDSISSETKHVTLRSSWRTRQGLPSLEDSQIKVEKNAASSPTNACRSSVDLSEMEGSSTRTNSLEQSSARSGATTNSWSAPEMGSRRTKSNLSASELLTRRSYTSDPTTASPWHRTTLPAHGSRAEFCPPSLTVQCPHGLLS", "length": 1066, "header": "tr|A0A8V0YUS4-1|A0A8V0YUS4_CHICK Computationally mapped isoform of Leucine zipper protein 1 OS=Gallus gallus OX=9031 GN=LUZP1 PE=1 SV=1 CANONICAL=A0A8V0YPS1-1" }, "locus": { "chromosome": "23", "start_pos": 2056726, "end_pos": 2051243, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034047.1", "url": "https://www.ensembl.org/id/ENSGALT00010034047.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020010.1", "url": "https://www.ensembl.org/id/ENSGALP00010020010.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:428210", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:428210", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3L7I8J7-1", "protein_name": "Leucine zipper protein 1 isoform X1", "gene_name": "Luzp1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MADMASYKDAASSRHLRFKLQSLSRRLDELEEATKNLQKAEDELLDLQEKVIQAEGSNSSMLAEIEVLRQRVLKIEGKDEEIKRAEDLCHTMKEKLEEEENLTRELKSEIEWLQKRMADLEKLEEALSRSKNECSQLCLSLNEERNLTKKISSELEMLRVKVKELESSEDRLDKTEQSLVSELEKLKSLTLSFVNERKYLNEKEKENEKLIKELTQKLEQNKKMSRDHTRNASTLLERNDLRIEDGISSTLPSKELRRKGSLDYLKQVENETRDKSENEKNQNQEDNKVKDLNQEIQKLKTQIKHFESLEEELKKMRAKNNDLQDNYLTELNKNKILASQLEEIKLQVKKQKELGNGDIEGEDAFLLGRGRHERTKLRGHGGEASVSRHIPRELSPQHKRERIRNREFALNNENYSLSNKQASSIFTNRRAAKASNMGVGADNGSQETKRAEDRFLPGSSQSEGKKCREQPSVLSRYPPAAQEHNKVWKGTLKPGTESGLKGKVEKTTRTFSDSTHGPVPNDTMGRGDKTSEISEAHYGKRGQVPGNGSQVTQAAESGCSKATGALSSSQRASSEGISKSKRAANGLEADANFPNSKAPILSKYPYSSRSQENIPQGFSVPNKEGLDQSVAVVMEDSSQHEALRCRVIKSSGKEKPDSDDDLDIESLVTAKLVNTTITPEPEPKQQPNSREKVKSRGPRTALFENDKNAATENESMKSTRASSSAVEFPDANGVGAKNQRLFSPREALRSRAIIKPVIIDKDVKKIMGGSGTEVVLEKQRSTSNPVPSKVTSSITIYPSESSGPRAVQGEAPRERHTSTSNIQVGHPELTSVSNHVNSPLELSIHKHDITLQLTEAERMGDGSPKNRPETVVSRSSILIKPSDSVERNSHAPQAETVRWKSHNASSEVGSSDTRHVTVRNAWKSKRDFKCSEDVPTRVGRHMESTNAYTQRSSTDFLELEQPRSLPSEQGTRKVGDAGDAPELSSRRTQSSLTASEVITRRNRIGDAITATTWNHSASLEEGEDGTSVTSRRMHNTLEHSELPGKQGLPEPGIWAEERLQPARPYAEED", "length": 1069 }, "evidence": [ { "id": "A0A8V0YPS1", "url": "https://omabrowser.org/oma/group/A0A8V0YPS1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8N7UVR0-1", "protein_name": "Leucine zipper protein 1", "gene_name": "luzp1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTDTTNRHLRHKLQSLGRRLDELEEAKGKLQKAEDELLDIQDKIIQAEGSNSSLLTDVETMRKRLLKIEGKDEEVRKAEDLCREVREKLDQEEKLTKDFKVDIERLQRRMTELEKLEEAFGKSKSDCTQLCLSLNEEKNLTKKLAAELDALKARVKEVDASEGRLDKAEKSLTAEMEKLKSLTQTFMNERKRLLDKQREDDKIILRLTEKLERQKNKVGTTDHSRTDSRDLRIEDELSSGLTCKLARKKSLDYLKHSDDFDLRNESENEKNCLQGQEDNKVKDLSQEVERLKNRLKQMELVEEDLRNMESKNTELIEKYQQERNRSQALHDQVEQMRMELNVCSTSNGNSAITSTTKVLENGKAENEEFNVRGGFRQDKPKFLNRSPASSEQVTSKYKSRDSSPQQRRETKLRNKDLCHSRESSPKTVRRTLGPAHNVRKGQKTGASNTSDNGTRDGKKEEKNASASSCALSESKKVSVLSRYPPAVNDQRSWRPSVKQNDNDGKKSRVEKLSKCPGSDNESSNSDGTHFNSARATIVASPEKGLTEPESLDQDTSAVLSLSKANGSYTAYRSHVSPSFLTDHGSDGHSSASETESTGSRRSVGEQSDPLVSSTSGRTSKYTRYSRLQDSYSDASSKSPFSEEQQRPLTMEEEAQETAHSSSGIEVRRVCSPRESLQSKAVIKQAIVEIDRKEVMSGGTTEALTTSGKPKISTKPVLTSKMTSSITFYPNDPSSSRTSSRSSSLSSEPPSKERHTSTSNIVIGPSSEHRGSISIPYEISIPKSELTLRQSETDTDFSEPHSYLETAPLEATLLSQNSFSLQSSDASDFNNDIESGFESSSSSTTVTSWRSHAHNHLSYDDSLPEMRNITVRSTWKSRGAASVDESVRALRQDGSEDESESSTTWRAYRATTVLDTPANSSIGANCANKPSPAEVYMRRINNSASSVPEPGRRNKKTPSPERAIAHEPVSAQQLQPRVRKQPLSVDDRDPALSSWRRQPAGDLDPYDRPGSRGAWSSRNRTADGSRSWSNRHLDN", "length": 1034 }, "evidence": [ { "id": "A0A8V0YPS1", "url": "https://omabrowser.org/oma/group/A0A8V0YPS1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AAA9S794-1", "protein_name": "Leucine zipper protein 1", "gene_name": "LUZP1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAEFTSYKDTASSRHLRFKLQSLSRRLDELEEATKNLQKAEDELLDLQDKVIQAEGSNSSMLAEVEVLRQRVLRIEGKDEEIKKAEDLCQLMKEKLEEEENLTRELKSEIERLQKRMAELEKLEEAFSRSKNDCTQLCLSLNEERNLTKKISSELEMLRIKVKELESSEDRLDKTEQSLVSELEKLKSLTLSFVSERKYLNEKEKENEKLIKELTQKLEQNKKMNRDYTRNASNLLERNDLRIEDGISSPLPSKESRRKGALDYLKLAENETRNKSENEKNRNQEDNKVKDLTQEIEKLKTQIKHFESLEEELKKMRAKNNDLQDNYLSEQNKNKLLASQLEEIKLQIKKQKELENGEVEGEDAFLSGRGRHERTKLRGHGSEASAKHMARELSPQHKRERHCNRELTLNNENPLKNRQVSSPSFTNRKTAKASHAGAGADSGAQETRRTEDRFTAGSSQSEGKKSREQPPVLSRYPPAAQEHSKVWKGAPKPGTESGLKGKVEKATRTFSDNTHGSVSNDVSGRGDKASETSTEAPFGKRGQVPGSGSQITQAADAGSSKAVGALATSRRSSSEGLSKGKKATSGLEADTSFPSSKTPPLSKYPYSSRSQENILQGFSTPSKEGVEQPVAVVMEDSSQHEALRCRVTKSSGREKPDSDDDMDMVSLVTAKLVNTTITPEPEPPHQPQSREKAKSRGAVRASLFENDKDIGTENESGKAVRASANAMELPEANGSGAKSQRPFSPREALRSRAIIKPVIIDKDVKKIMGGSGTEAALEKQKSASKPGPNKVTSSITIYPSDSGSPRAAPGEAARERHTSTSNIQVGLPELASVSNHVSSPFELSIHKHDITLQLSEAERTGDGSLKNRPETVVSRSSIIIKPSDPVERNSHAPTVETIRWKSHSAPLEAGSPDARHITVRNAWKSRRDLNSSEDSPARVGRHVESPNPHTQRSSSDCSDPEQPGSYLSEQGTRRGGTSGEVPELASRRTQSSLAVSEVFTRRSRAGDAVPAEAWNHLAGTVGPASPPCPLLLPPSPFPSVLSSWFSSAPACVTRDAGDFGVRKH", "length": 1064 }, "evidence": [ { "id": "A0A8V0YPS1", "url": "https://omabrowser.org/oma/group/A0A8V0YPS1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "I3LNF8-1", "protein_name": "Leucine zipper protein 1", "gene_name": "LUZP1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAEFTSYKDTASSRHLRFKLQSLSRRLDELEEATKNLQKAEDELLDLQDKVIQAEGSNSSMLAEIEVLRQRVLRIEGKDEEIKRAEDLCQLMKEKLEEEENLTRELKSEIERLQKRMAELEKLEEAFSRSKNDCTQLCLSLNEERNLTKKISSELEMLRVKVKELESSEDRLDKTEQSLVSELEKLKSLTLSFVSERKYLNEKEKENEKLIKELTQKLEQNKKMNRDYTRNASNLLERNDLRIEDGISSLPSKESRRKGTLDYLKQVENETRNKSENEKNRNQEDNKVKDLNQEIEKLKTQIKHFESLEEELKKMRAKNNDLQDNYVREQNKNKLLASQLEEIKLQIKKQKELENGEVEGEDALLSSKGRHERTKFRGHANEASVSKHTPRELSPQHKRERHRNREFAINNENYSLSNRQVSSPSFTSRRTAKASNTGAGVDSGTQETKRTEDRFTSGSSQSEGKKSREQPSVLSRYPPAAQEHSKVWKGTPRPGTEGGLKGKVEKTTRTFSDTSHGSVPNDISGRGDKTSDASAEALLSKRGQVPGNGSQITQAADSGSSKAIGALATSRRSSSEGLSKGKKAANGPESDTNSPNSKAPPLSKYSYSSRSQENILQGFSTPNKEGVDQPVAVVMEDSSQHEALRCRVIKSSGREKPDSDDDMDTVSLVTAKLVNTTITPEPEPKQQPNSREKAKSRGGLRPSLFENDKDVGTENESGKPVRASTNAMELPEANGAGVKNQRPFSPREALRSKAIIKPVIIDKDVKKIMGGSGTEATLEKQKPTSRPGPNKVTSSITIYPSDSSSPRAAPGEALRERHTSTSNIQVGPPDLTALSNHISSPFELSIHKHDFTLQFTEAERPGEGPLKNKPETVVSRSSIIIKPSEPVERNSHAPAAETIRWKSHSAPLEVGSSDARHVTVRNAWKSRRDLNSFEDPPTRIGKNVESTNAYTQRSSTDYSDLEQPGSYLSEQGTRRVGNSGDAPELSSRRTQSSLTVSEVLTRRNRVGDAVTAPAWNHSAGTEEGDDCTLGVYRRLHNSLERSELSAKQGLPEPGRARGEERLRPSRPCAEEN", "length": 1072 }, "evidence": [ { "id": "A0A8V0YPS1", "url": "https://omabrowser.org/oma/group/A0A8V0YPS1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q86V48-1", "protein_name": "Leucine zipper protein 1", "gene_name": "LUZP1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAEFTSYKETASSRHLRFKLQSLSRRLDELEEATKNLQKAEDELLDLQDKVIQAEGSNSSMLAEIEVLRQRVLRIEGKDEEIKRAEDLCRLMKEKLEEEENLTRELKSEIERLQKRMAELEKLEEAFSRSKNDCTQLCLSLNEERNLTKKISSELEMLRVKVKELESSEDRLDKTEQSLASELEKLKSLTLSFVSERKYLNEKEKENEKLIKELTQKLEQNKKMNRDYTRNASNLERNDLRIEDGISSTLPSKESRRKGGLDYLKQVENETRNKSENEKNRNQEDNKVKDLNQEIEKLKTQIKHFESLEEELKKMKSKNNDLQDNYLSEQNKNKLLASQLEEIKLQIKKQKELENGEVEGEDAFLSSKGRHERTKFRGHGSEASVSKHTARELSPQHKRERLRNREFALNNENYSLSNRQVSSPSFTNRRAAKASHMGVSTDSGTQETKKTEDRFVPGSSQSEGKKSREQPSVLSRYPPAAQEHSKAWKGTSKPGTESGLKGKVEKTTRTFSDTTHGSVPSDPLGRADKASDTSSETVFGKRGHVLGNGSQVTQAANSGCSKAIGALASSRRSSSEGLSKGKKAANGLEADNSCPNSKAPVLSKYPYSCRSQENILQGFSTSHKEGVNQPAAVVMEDSSPHEALRCRVIKSSGREKPDSDDDLDIASLVTAKLVNTTITPEPEPKPQPNSREKAKTRGAPRTSLFENDKDAGMENESVKSVRASTNTMELPDTNGAGVKSQRPFSPREALRSRAIIKPVIVDKDVKKIMGGSGTETTLEKQKPVSKPGPNKVTSSITIYPSDSSSPRAAPGEALRERHTSTSNIQVGLAELTSVSNHVSSPFELSIHKHDITLQLAEAERMADGPLKDRPETVVSRSSIIIKPSDPVERNSHAPPAETIRWKSHSAPSEVGFSDARHVTVRNAWKSRRDLKSLEDPPTRIGKNVESTNSNAYTQRSSTDFSELEQPRSCLFEQGTRRVGPSSGDAPEPSSRRTQSSLTVSEVLTRRNRVGDTITVAAWNHSASMEEEGEDCTLSVYRQLHNSLDPSELPGKQGLPESGRVRAEERLRPTRPCAEEN", "length": 1076 }, "evidence": [ { "id": "A0A8V0YPS1", "url": "https://omabrowser.org/oma/group/A0A8V0YPS1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8R4U7-1", "protein_name": "Leucine zipper protein 1", "gene_name": "Luzp1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAELTNYKDAASNRHLRFKLQSLSRRLDELEEATKNLQRAEDELLDLQDKVIQAEGSDSSTLAEIEVLRQRVLKIEGKDEEIKRAEDLCHTMKEKLEEEENLTRELKSEIERLQKRMVDLEKLEEALSRSKNECSQLCLSLNEERNLTKKISSELEMLRVKVKELESSEDRLDKTEQSLVSELEKLKSLTLSFVNERKYLNEKEKENEKIIKELTQKLEQNKKMNRDHMRNASTFLERNDLRIEDGISSTLSSKESKRKGSLDYLKQVENETRDKSENEKNRNQEDNKVKDLNQEIEKLKTQIKHFESLEEELKKMRAKNNDLQDNYLTELNRNRSLASQLEEIKLQVRKQKELGNGDIEGEDAFLLGRGRHERTKLKGHGSEASVSKHTSRELSPQHKRERLRNREFALSNEHYSLSSKQASSPVFTNKRAAKASNMGMGTDSGTQETKRTEDRFAPGSSHSEGKRGREQPSVLSRYPPAAQEHTKVWKGAPKPGTESGLKGKVEKTTRTFSDSTHVSVPNDIVGKGDKTSDLSSEAHCGKRGQVPGHASQGTQAVESSCSKAIGALSSSQKASSEGLSKGKKTANGLAADANFSNSKAPILSKYPYSSRSQENILQGFSLPNKEGVDQPVAVVMEDSSQHEALRCRVIKSSGREKPDSDDDLDIESFVTAKLVNTTITPEPEPKPQPNSREKVKSRGGTRTALFENDKNAAIENDSVKPTRPSSNAIEFPDANCAGVKNQRPFSPREALRSRAIIKPVIIDKDVKKIMGGSGTEVVLEKQKSTSKSVTSKVTSSITIYPSDSSGPRAVPSEAPRERHTSTSNIQVGPPELTAISNHVSSPLELSIHKHDITLQLTEAERVGDGSPKNRAEMVVSRSSILIKPSESVEKNSHVPPAETIRWKSHSASSDSRHITVRNAWKSKRDLKCSEDPPTGIGRNMEATNAYTQRPCTDFLELEQPRSQPSEQGARRVGNSGDAPELSPRRTQSSLTASEVLTRRDRMGGAITAASCNHSSSMEEGEDSTFVTSRRIHNPLEHSELPGKQGLPEPEPVWTEERLHPAKPYAEED", "length": 1068 }, "evidence": [ { "id": "A0A8V0YPS1", "url": "https://omabrowser.org/oma/group/A0A8V0YPS1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9ESV1-1", "protein_name": "Leucine zipper protein 1", "gene_name": "Luzp1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MADIANYKDAASNRHLRFKLQSLSRRLDELEEATKNLQKAEDELLDLQDKVIQAEGSNSSMLAEIEVLRQRVLKIEGKDEEIKRAEDLCHTMKEKLEEEENLTRELKSEIDRLQKRMADLEKLEEALSRSKNECSQLCLSLNEERNLTKKISSELEMLRVKVKELESSEDRLEKTEQSLVSELEKLKSLTLSFVNERKYLNEKEKENEKLIKELTQKLEQNKKINRDHMRNASTFLERNDLRIEDGISSTLPSKESRRKGSLDYLKQVENETRDKSENEKNRNQEDNKVKDLNQEIEKLKTQIKHFESLEEELKKMRAKNNDLQDNYLTELNKNRSLASQLEEVKLQVKKQKELGNGDIEGEDAFLLGRGRHERTKLKGHGGEVSVSKHTSREQSPQHKRERLRNRGFALNDEHCSLSNKQVSSPAFTNKRAAKASNMGVGPDSGTQETKRTEDRLAPGSSQSEGKKGREQPSVLSRYPPAAQDHTKVWRGNPKPGTESGLKGKVEKTTRTFSDSAHGSVPNDVVGKGDKTSDFSSEAHCGKRGQVPGHASQVTQVAESGCSKAIGALASSQRASSEGLSKGKKAANGLETDANFPHSKAPILSKYPYSSRSQENILQGFSVPNKEGVDHSVAVVMEDSSQHEALRCRVIKSSGREKPDSDDDLDIESLVTAKLVNTTITPEPEPKLQPNSREKVKSRGGTRTPLFENDKNAAVENDSAKSMRSSSNAVEFPDANCAGVKNQRPFSPREALRSRAIIKPVIIDKDVKKIMGGSGTEVVLEKQKSTPKSVTSKVTSSITIYPSDSSGPRAVPTEAPRERHTSTSNIQVGPPELTSVSNHISSPLELSIHKHDITLQLTEAERVGDGSPKNRAETVVSRSSILIKPSDSVERNSHAFPAETIRWKSHSTSSEVASSDTRHITVRNAWKSKRDLKCSEDPPTRIGRNVEATNAYTQRSSTDFLELEQPRSHPPEQGTRKVGNSGDAPELSSRRTQSSLTASEVLTRRNRIGDAVTAASWNHSSNVVSLTFLPSALICLTEDLGNTEGWEMLNLR", "length": 1051 }, "evidence": [ { "id": "A0A8V0YPS1", "url": "https://omabrowser.org/oma/group/A0A8V0YPS1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "protein localization to actin cytoskeleton", "id": "GO:1903119", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903119", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPS1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPS1" } ], "pmid": "" }, { "name": "negative regulation of cilium assembly", "id": "GO:1902018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902018", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPS1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPS1" } ], "pmid": "" }, { "name": "stress fiber assembly", "id": "GO:0043149", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043149", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPS1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPS1" } ], "pmid": "" }, { "name": "apical constriction", "id": "GO:0003383", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003383", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPS1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPS1" } ], "pmid": "" }, { "name": "regulation of protein complex stability", "id": "GO:0061635", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061635", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPS1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPS1" } ], "pmid": "" }, { "name": "contractile ring contraction", "id": "GO:0036213", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036213", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPS1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPS1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 10, "go_terms": [ { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPS1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPS1" } ], "pmid": "" }, { "name": "actin filament", "id": "GO:0005884", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005884", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPS1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPS1" } ], "pmid": "" }, { "name": "actin cytoskeleton", "id": "GO:0015629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015629", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPS1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPS1" } ], "pmid": "" }, { "name": "spindle midzone", "id": "GO:0051233", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051233", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPS1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPS1" } ], "pmid": "" }, { "name": "chromosome, centromeric region", "id": "GO:0000775", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000775", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPS1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPS1" } ], "pmid": "" }, { "name": "stress fiber", "id": "GO:0001725", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001725", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPS1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPS1" } ], "pmid": "" }, { "name": "midbody", "id": "GO:0030496", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030496", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPS1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPS1" } ], "pmid": "" }, { "name": "ciliary basal body", "id": "GO:0036064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036064", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPS1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPS1" } ], "pmid": "" }, { "name": "tight junction", "id": "GO:0070160", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070160", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPS1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPS1" } ], "pmid": "" }, { "name": "CERF complex", "id": "GO:0090537", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090537", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPS1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPS1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "microtubule binding", "id": "GO:0008017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008017", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPS1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPS1" } ], "pmid": "" }, { "name": "actin filament binding", "id": "GO:0051015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051015", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPS1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPS1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1015, "end_pos": 1017, "annotation": "n_glycosylation_sequon" }, { "start_pos": 145, "end_pos": 147, "annotation": "n_glycosylation_sequon" }, { "start_pos": 231, "end_pos": 233, "annotation": "n_glycosylation_sequon" }, { "start_pos": 278, "end_pos": 280, "annotation": "n_glycosylation_sequon" }, { "start_pos": 282, "end_pos": 284, "annotation": "n_glycosylation_sequon" }, { "start_pos": 420, "end_pos": 422, "annotation": "n_glycosylation_sequon" }, { "start_pos": 57, "end_pos": 59, "annotation": "n_glycosylation_sequon" }, { "start_pos": 606, "end_pos": 608, "annotation": "n_glycosylation_sequon" }, { "start_pos": 675, "end_pos": 677, "annotation": "n_glycosylation_sequon" }, { "start_pos": 868, "end_pos": 870, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1015, "end_pos": 1017 }, { "start_pos": 145, "end_pos": 147 }, { "start_pos": 231, "end_pos": 233 }, { "start_pos": 278, "end_pos": 280 }, { "start_pos": 282, "end_pos": 284 }, { "start_pos": 420, "end_pos": 422 }, { "start_pos": 57, "end_pos": 59 }, { "start_pos": 606, "end_pos": 608 }, { "start_pos": 675, "end_pos": 677 }, { "start_pos": 868, "end_pos": 870 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YPS3-1", "uniprot_ac": "A0A8V0YPS3", "uniprot_id": "A0A8V0YPS3_CHICK", "mass": { "chemical_mass": 62182.0, "monoisotopic_mass": 62182.0 }, "refseq": {}, "gene_names": [ { "name": "LRRC15", "type": "recommended", "evidence": [ { "id": "A0A8V0YPS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPS3" } ] } ], "protein_names": [ { "name": "Leucine rich repeat containing 15", "type": "synonym", "evidence": [ { "id": "A0A8V0YPS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPS3/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPS3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPS3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LRRC15", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPS3", "locus": { "chromosome": "9", "start_pos": 12598606, "end_pos": 12580961, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010014767", "url": "https://www.ensembl.org/id/ENSGALG00010014767" } ] } } ], "crossref": [ { "id": "IPR001611", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001611", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003591", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003591", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050541", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050541", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR24369", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24369", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24369:SF213", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24369:SF213", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00560", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00560", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13855", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13855", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YPS3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPS3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YPS3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPS3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEQGGWWLLLLLLGFHPARGQCPEQCQCVRTAQVECSGASITAVPSPIPTNAVTLQIVNTRITELGEASFGNASLLIGLRIEKNDLRRVSPDAFQHLPDLRYLSLASNKLQELPVQVFQPLGKLESLLLSSNQLLRVEPDHFAHLSNLKELQLHGNNLRELTEGLFDQLASLTKLNLARNNLDRLPPRAFERLPQLQVLRLYENRLRHIPAGAFDTLPELQELGLHQNQLETLSPELFVHNGNLQKLYLSNNLLTALPAGIFLPLRALSKITLHVNRLRDISPAAFGPMPNLRELWLYENELAALPAAVFSNLTQLQLLVLSKNQLRSLAPGAFRGLGELLELSLHSNALRWLDAGVLGGMPKLQNISLQNNRLQTLPRGLFAATPRLQHIQLHVNTLENLPNGIFSPLAAVREVKLHNNSWRCDHDILPLRAWLEANPSKVGETPPVCAQPAPLRGTPIAGLWQDQLPTAWPSSPLPALPSQEALPSGPPTTLLATPVSQEEEEEEEGRGWWGLTRTQSAVVGAVIVLVCVALLCALVALVVYGCRKKSHVVLMRMKAPNEA", "length": 563, "header": "tr|A0A8V0YPS3-1|A0A8V0YPS3_CHICK Isoform 1 of Leucine rich repeat containing 15 OS=Gallus gallus OX=9031 GN=LRRC15 PE=1 SV=1 CANONICAL=A0A8V0YPS3-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YPS3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPS3/entry#A0A8V0YPS3-1", "sequence": { "sequence": "MEQGGWWLLLLLLGFHPARGQCPEQCQCVRTAQVECSGASITAVPSPIPTNAVTLQIVNTRITELGEASFGNASLLIGLRIEKNDLRRVSPDAFQHLPDLRYLSLASNKLQELPVQVFQPLGKLESLLLSSNQLLRVEPDHFAHLSNLKELQLHGNNLRELTEGLFDQLASLTKLNLARNNLDRLPPRAFERLPQLQVLRLYENRLRHIPAGAFDTLPELQELGLHQNQLETLSPELFVHNGNLQKLYLSNNLLTALPAGIFLPLRALSKITLHVNRLRDISPAAFGPMPNLRELWLYENELAALPAAVFSNLTQLQLLVLSKNQLRSLAPGAFRGLGELLELSLHSNALRWLDAGVLGGMPKLQNISLQNNRLQTLPRGLFAATPRLQHIQLHVNTLENLPNGIFSPLAAVREVKLHNNSWRCDHDILPLRAWLEANPSKVGETPPVCAQPAPLRGTPIAGLWQDQLPTAWPSSPLPALPSQEALPSGPPTTLLATPVSQEEEEEEEGRGWWGLTRTQSAVVGAVIVLVCVALLCALVALVVYGCRKKSHVVLMRMKAPNEA", "length": 563, "header": "tr|A0A8V0YPS3-1|A0A8V0YPS3_CHICK Isoform 1 of Leucine rich repeat containing 15 OS=Gallus gallus OX=9031 GN=LRRC15 PE=1 SV=1 CANONICAL=A0A8V0YPS3-1" }, "locus": { "chromosome": "9", "start_pos": 12597254, "end_pos": 12595566, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010035555.1", "url": "https://www.ensembl.org/id/ENSGALT00010035555.1" }, { "database": "Ensembl 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"expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPU2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPU2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MPST", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPU2", "locus": { "chromosome": "1", "start_pos": 51548866, "end_pos": 51551784, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010014801", "url": "https://www.ensembl.org/id/ENSGALG00010014801" } ] } } ], "crossref": [ { "id": "A0A8V0YPU2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YPU2", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd01448", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01448", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd01449", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01449", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "418048", "url": "https://www.ncbi.nlm.nih.gov/gene/418048", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001307", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001307", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001763", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001763", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036873", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036873", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045078", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045078", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "NNNWFAS", "url": "https://omabrowser.org/oma/group/NNNWFAS/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YPT3", "url": "https://www.orthodb.org/?gene=A0A8V0YPT3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YPU2", "url": "https://www.orthodb.org/?gene=A0A8V0YPU2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11364", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11364", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11364:SF25", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11364:SF25", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00581", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00581", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-1614558", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1614558", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YPT3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPT3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YPT3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPT3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YPU2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPU2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YPU2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPU2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAARGRAAPPRWECPGSRPLKRRRPRLLGSCSAEARHRGVSGSLSQDLGAMSQQLLYRALVSAKWLSEAIKSKQTGQALKVVDASWYLPKMKRDPKQEFEERHIPGAVFFDIDQCSDRTSPYDHMMPKANEFAEYVGKLGVGNDSHVVVYDGSDQGLFSAPRVWWMFRVFGHEAVSLLDGGLKNWLREGFPLSSGKTQVAPSDFHATLDKCMVKTYEDILDNLDSHRFQVVDARVEGRFRGIEPEPRDGIEPGHIPGSLNMPFTSFLTESGLEKTPEQIRSLFQEKKVDLSKPLVATCGSGVTACHVALGAYLCGKPDVAVYDGAWVEWYMRAQPENIISEGKGKTV", "length": 347, "header": "tr|A0A8V0YPU2-1|A0A8V0YPU2_CHICK Isoform 1 of Sulfurtransferase OS=Gallus gallus OX=9031 GN=MPST PE=1 SV=1 CANONICAL=A0A8V0YPU2-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YPT3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPU2/entry#A0A8V0YPT3-1", "sequence": { "sequence": "MAGVSGSLSQDLGAMSQQLLYRALVSAKWLSEAIKSKQTGQALKVVDASWYLPKMKRDPKQEFEERHIPGAVFFDIDQCSDRTSPYDHMMPKANEFAEYVGKLGVGNDSHVVVYDGSDQGLFSAPRVWWMFRVFGHEAVSLLDGGLKNWLREGFPLSSGKTQVAPSDFHATLDKCMVKTYEDILDNLDSHRFQVVDARVEGRFRGIEPEPRDGIEPGHIPGSLNMPFTSFLTESGLEKTPEQIRSLFQEKKVDLSKPLVATCGSGVTACHVALGAYLCGKPDVAVYDGAWVEWYMRAQPENIISEGKGKTV", "length": 311, "header": "tr|A0A8V0YPT3-1|A0A8V0YPU2_CHICK Computationally mapped isoform of Sulfurtransferase OS=Gallus gallus OX=9031 GN=MPST PE=1 SV=1 CANONICAL=A0A8V0YPU2-1" }, "locus": { "chromosome": "1", "start_pos": 51551280, "end_pos": 51549596, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010035606.1", "url": "https://www.ensembl.org/id/ENSGALT00010035606.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020674.1", "url": "https://www.ensembl.org/id/ENSGALP00010020674.1" } ] } }, { "isoform_ac": "A0A8V0YPU2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPU2/entry#A0A8V0YPU2-1", "sequence": { "sequence": "MAARGRAAPPRWECPGSRPLKRRRPRLLGSCSAEARHRGVSGSLSQDLGAMSQQLLYRALVSAKWLSEAIKSKQTGQALKVVDASWYLPKMKRDPKQEFEERHIPGAVFFDIDQCSDRTSPYDHMMPKANEFAEYVGKLGVGNDSHVVVYDGSDQGLFSAPRVWWMFRVFGHEAVSLLDGGLKNWLREGFPLSSGKTQVAPSDFHATLDKCMVKTYEDILDNLDSHRFQVVDARVEGRFRGIEPEPRDGIEPGHIPGSLNMPFTSFLTESGLEKTPEQIRSLFQEKKVDLSKPLVATCGSGVTACHVALGAYLCGKPDVAVYDGAWVEWYMRAQPENIISEGKGKTV", "length": 347, "header": "tr|A0A8V0YPU2-1|A0A8V0YPU2_CHICK Isoform 1 of Sulfurtransferase OS=Gallus gallus OX=9031 GN=MPST PE=1 SV=1 CANONICAL=A0A8V0YPU2-1" }, "locus": { "chromosome": "1", "start_pos": 51551780, "end_pos": 51549596, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010035610.1", "url": "https://www.ensembl.org/id/ENSGALT00010035610.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020677.1", "url": "https://www.ensembl.org/id/ENSGALP00010020677.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-1614558", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1614558", "resource": "Reactome", "description": "Degradation of cysteine and homocysteine" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A286ZTN2-1", "protein_name": "Mercaptopyruvate sulfurtransferase", "gene_name": "MPST", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAPQQLFRALVSAQWVAEALRAPRAGQPLQLLDASLYLPKQGRDARLEFEARHIPGAAFFDLDQCSDRTSPYDHMLPSAAQFAEYTGRLGVSAATHVVVYDASDQGLYAAPRVWWMFRAFGHRTVSLLDGGLRNWLRQGLPLSAGKSRPVPAEFHAVLDPTYVKTYEDIKENLESRRFQVVDARATGRFRGTEPEPRDGIEPGHIPGTINIPFTEFLTPEGLEKSPEEIRRLFQEKKVDLSLPLVATCGSGVTACHVALGAYLCGKPDVPIYNGSWVEWYMRAQPEEIISEGRGKTH", "length": 297 }, "evidence": [ { "id": "A0A8V0YPU2", "url": "https://omabrowser.org/oma/group/A0A8V0YPU2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P25325-1", "protein_name": "3-mercaptopyruvate sulfurtransferase", "gene_name": "MPST", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MASPQLCRALVSAQWVAEALRAPRAGQPLQLLDASWYLPKLGRDARREFEERHIPGAAFFDIDQCSDRTSPYDHMLPGAEHFAEYAGRLGVGAATHVVIYDASDQGLYSAPRVWWMFRAFGHHAVSLLDGGLRHWLRQNLPLSSGKSQPAPAEFRAQLDPAFIKTYEDIKENLESRRFQVVDSRATGRFRGTEPEPRDGIEPGHIPGTVNIPFTDFLSQEGLEKSPEEIRHLFQEKKVDLSKPLVATCGSGVTACHVALGAYLCGKPDVPIYDGSWVEWYMRARPEDVISEGRGKTH", "length": 297 }, "evidence": [ { "id": "A0A8V0YPU2", "url": "https://omabrowser.org/oma/group/A0A8V0YPU2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P97532-1", "protein_name": "3-mercaptopyruvate sulfurtransferase", "gene_name": "Mpst", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAAPQLFRALVSAQWVAEALKSPRASQPLKLLDASWYLPKLGRDARREFEERHIPGAAFFDIDRCSDHTSPYDHMLPSATHFADYAGSLGVSAATHVVIYDGSDQGLYSAPRVWWMFRAFGHHSVSLLDGGFRYWLSQNLPISSGKSPSEPAEFCAQLDPSFIKTHEDILENLDARRFQVVDARAAGRFQGTQPEPRDGIEPGHIPGSVNIPFTEFLTSEGLEKSPEEIQRLFQEKKVDLSKPLVATCGSGVTACHVVLGAFLCGKPDVPVYDGSWVEWYMRAQPEHVISQGRGKTL", "length": 297 }, "evidence": [ { "id": "A0A8V0YPU2", "url": "https://omabrowser.org/oma/group/A0A8V0YPU2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q08686-1", "protein_name": "Sulfurtransferase TUM1", "gene_name": "TUM1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MPLFDLISPKAFVKLVASEKVHRIVPVDATWYLPSWKLDNKVDFLTKPRIPNSIFFDIDAISDKKSPYPHMFPTKKVFDDAMSNLGVQKDDILVVYDRVGNFSSPRCAWTLGVMGHPKVYLLNNFNQYREFKYPLDSSKVAAFSPYPKSHYESSESFQDKEIVDYEEMFQLVKSGELAKKFNAFDARSLGRFEGTEPEPRSDIPSGHIPGTQPLPYGSLLDPETKTYPEAGEAIHATLEKALKDFHCTLDPSKPTICSCGTGVSGVIIKTALELAGVPNVRLYDGSWTEWVLKSGPEWIAENRD", "length": 304 }, "evidence": [ { "id": "A0A8V0YPU2", "url": "https://omabrowser.org/oma/group/A0A8V0YPU2/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q54E40-1", "protein_name": "Sulfurtransferase", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MLKSLIININKSSVTSNNISKFSKVNQINRYFSSKMTNVGDRSKLFVSPKWLKENQNNVKIVDASWFMAHEKRDPRKEFVDKHIKSAKLFDIDEICDKTVSLPHNLPSEQVFEKEMKRLGITNDDHIIIYDTRAQYVASARVWWTFLIFGHSASKVSLLEGGLPAWEREGYPVQSGPIENSNNDESKTYKSTFNNDLVKNKQDILSNLQSKEYQLIDARSADRFWGRVDEPRPGLLRGHIPNSLNIPWTDLIEPVANGGHGGFIPNDKVLTTFKEKGVDLSSKIATTCGSGTTAAVLSLGLYKLGYPLAPIYDGSWSEWGLPVNKLPTSCSNN", "length": 333 }, "evidence": [ { "id": "A0A8V0YPU2", "url": "https://omabrowser.org/oma/group/A0A8V0YPU2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q99J99-1", "protein_name": "3-mercaptopyruvate sulfurtransferase", "gene_name": "Mpst", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAPQLFRALVSAQWVAEALKAPRSSQPLKLLDASWYLPKLGRDARREFEERHIPGAAFFDIDRCSDHTSPYDHMLPNATHFADYAGSLGVSAATHVVIYDDSDQGLYSAPRVWWMFRAFGHHSVSLLDGGFRHWLNQNLPISSGKSHSEPAEFSAQLDPSFIKTHEDILENLDARRFQVVDARAAGRFQGTQPEPRDGIEPGHIPGSVNIPFTEFLTNEGLEKSPEEIKRLFKEKKVDLSKPLVATCGSGVTACHVVLGAFLCGKSDVPVYDGSWVEWYMRAQPEHIISEGRGKTQ", "length": 297 }, "evidence": [ { "id": "A0A8V0YPU2", "url": "https://omabrowser.org/oma/group/A0A8V0YPU2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPU2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPU2" } ], "pmid": "" }, { "name": "neuron projection", "id": "GO:0043005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043005", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPU2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPU2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "thiosulfate-cyanide sulfurtransferase activity", "id": "GO:0004792", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004792", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPU2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPU2" } ], "pmid": "" }, { "name": "3-mercaptopyruvate sulfurtransferase activity", "id": "GO:0016784", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016784", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPU2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPU2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "tRNA wobble position uridine thiolation", "id": "GO:0002143", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002143", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPU2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPU2" } ], "pmid": "" }, { "name": "hydrogen sulfide biosynthetic process", "id": "GO:0070814", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070814", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPU2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPU2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 143, "end_pos": 145, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YPU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPU2" }, { "id": "PS50206", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50206" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Rhodanese", "eco_id": "ECO_0000259", "start_pos": 75, "end_pos": 194, "start_aa": "Thr", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 143, "end_pos": 145 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", 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This record is derived from a genomic sequence (NC_052554.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015153278", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015153278" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPU7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPU7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MAP7D1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPU7", "locus": { "chromosome": "23", "start_pos": 4441575, "end_pos": 4453335, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010014806", "url": "https://www.ensembl.org/id/ENSGALG00010014806" } ] } } ], "crossref": [ { "id": "A0A8V0YPU7", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YPU7", "database": "AlphaFoldDB", "categories": [] }, { "id": "419624", "url": "https://www.ncbi.nlm.nih.gov/gene/419624", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR008604", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008604", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051483", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051483", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:419624", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419624", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MERSCAG", "url": "https://omabrowser.org/oma/group/MERSCAG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YPU7", "url": "https://www.orthodb.org/?gene=A0A8V0YPU7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15073", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15073", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15073:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15073:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05672", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05672", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015153278", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015153278", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YPU7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPU7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YPU7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPU7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MESGRAGREPQPRAAPGKTPSPMGDSVLPPPRGDTVHGDSPPQCDRPVLPAVTPSPMATPPPGQLCPVPAAVTPPGQPMSPIPAAVAPSAESVPPWCDKTPPAPPHPPTTEQPKEEASPSTAGQPLPVPTAPCPAETLPHGSTLMAPTSGKGAPSDAKSPLGSTARPPKDAPPKDVPPKDVSPKDAPSKDIHPKDTPSKDVPPKDASPKDTPSKDVAPKDVLPKDVTPKDVPPKGDRATPAAASPSSAASPRPKQADAQKAQARHRQAKERREERAKYLAAKRALWLEKEEKAKVLRERQLEERRRRLEEQRLRAEKRRAVLEERQRQKLEKNKERYEAAIQRSAKKTWAEIRQQRWSWAGALHHGSAAHKDGASRCSVSAVNLPKHVDSIINKRLSKSSATLWNSPSRNRSLQLSPWESSIVDRLMTPTLSFLARSRSAVTLAGNGKEQVPVCPRSASASPLSPCHNHRLPHRCWERRRGTAGSPDVTPRRRAESSPKKKEKKEKERENAKERSALSHERSLKKRQSLPGAQPRLLPTADSSPGPKNRPSSPATPKTRPASPSPALGSPHKPPLPRSAHSSPKVRARARDERGEQDGQAKGRERKEEEKGPATPEPPRVPTEPAAAPSAPAAHSPPSRPSAGTTDREEAARLLAEKRRQAREQREREERERREQEEQERRLQEERAQRAAEEQSRREALARQREEERQLQEEREAQEKARAEREETERLQRQREEAEAKAREEAERQRLEREKHFQREEQERLERKKRLEEIMKRTRKSDASDAKKKEDKKIVNGKAVEQEHSTGGEKRAGPMPKAEELPETETPSAGTLGTLKGPAGEGLQPSSPAKDVAAPVVNGVQPSKHENGFSGTEGSSELLELSHHGGSPSSIIPFGDKEPFLKQAVVKPPQVTEVL", "length": 914, "header": "tr|A0A8V0YPU7-1|A0A8V0YPU7_CHICK Isoform 1 of MAP7 domain containing 1 OS=Gallus gallus OX=9031 GN=MAP7D1 PE=1 SV=1 CANONICAL=A0A8V0YPU7-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YPU7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPU7/entry#A0A8V0YPU7-1", "sequence": { "sequence": "MESGRAGREPQPRAAPGKTPSPMGDSVLPPPRGDTVHGDSPPQCDRPVLPAVTPSPMATPPPGQLCPVPAAVTPPGQPMSPIPAAVAPSAESVPPWCDKTPPAPPHPPTTEQPKEEASPSTAGQPLPVPTAPCPAETLPHGSTLMAPTSGKGAPSDAKSPLGSTARPPKDAPPKDVPPKDVSPKDAPSKDIHPKDTPSKDVPPKDASPKDTPSKDVAPKDVLPKDVTPKDVPPKGDRATPAAASPSSAASPRPKQADAQKAQARHRQAKERREERAKYLAAKRALWLEKEEKAKVLRERQLEERRRRLEEQRLRAEKRRAVLEERQRQKLEKNKERYEAAIQRSAKKTWAEIRQQRWSWAGALHHGSAAHKDGASRCSVSAVNLPKHVDSIINKRLSKSSATLWNSPSRNRSLQLSPWESSIVDRLMTPTLSFLARSRSAVTLAGNGKEQVPVCPRSASASPLSPCHNHRLPHRCWERRRGTAGSPDVTPRRRAESSPKKKEKKEKERENAKERSALSHERSLKKRQSLPGAQPRLLPTADSSPGPKNRPSSPATPKTRPASPSPALGSPHKPPLPRSAHSSPKVRARARDERGEQDGQAKGRERKEEEKGPATPEPPRVPTEPAAAPSAPAAHSPPSRPSAGTTDREEAARLLAEKRRQAREQREREERERREQEEQERRLQEERAQRAAEEQSRREALARQREEERQLQEEREAQEKARAEREETERLQRQREEAEAKAREEAERQRLEREKHFQREEQERLERKKRLEEIMKRTRKSDASDAKKKEDKKIVNGKAVEQEHSTGGEKRAGPMPKAEELPETETPSAGTLGTLKGPAGEGLQPSSPAKDVAAPVVNGVQPSKHENGFSGTEGSSELLELSHHGGSPSSIIPFGDKEPFLKQAVVKPPQVTEVL", "length": 914, "header": "tr|A0A8V0YPU7-1|A0A8V0YPU7_CHICK Isoform 1 of MAP7 domain containing 1 OS=Gallus gallus OX=9031 GN=MAP7D1 PE=1 SV=1 CANONICAL=A0A8V0YPU7-1" }, "locus": { "chromosome": "23", "start_pos": 4453265, "end_pos": 4442104, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010035619.1", "url": "https://www.ensembl.org/id/ENSGALT00010035619.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020682.1", "url": "https://www.ensembl.org/id/ENSGALP00010020682.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 239, "start_aa": "Thr", "end_pos": 239, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr239", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 53, "start_aa": "Thr", "end_pos": 53, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr53", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 59, "start_aa": "Thr", "end_pos": 59, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr59", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 73, "start_aa": "Thr", "end_pos": 73, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr73", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:419624", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419624", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I5ZM56-1", "protein_name": "MAP7 domain-containing protein 1", "gene_name": "Map7d1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MESGPRVEPGPGAPAAVLARIPQEPRPSPEGDPSPPPPPTPMSALVPDTPPDTPPAMKNASTPQQLPLEPVSPTGQVSPQPAPPPDECPSSEAKSRGPTPTATGPRDAKPSQRSSQPSPTAVPASDSPSAKQDVKKAGERHKLAKERREERAKYLAAKKAVWLEKEEKAKALREKQLQERRRRLEEQRLKAEQRRAALEERQRQKLEKNKERYEAAIQRSVKKTWAEIRQQRWSWAGALHHNSPGRKTSGSRCSVSAVNLPKHVDSIINKRLSKSSATLWNSPSRNRSLQLSAWESSIVDRLMTPTLSFLARSRSAVTLPRNGRDQGRGSGPGRRPTRARAGASLAPGPHPDRTHPSAAVPVCPRSASASPLTPCSAPRSAHRCTPSGERPERRKPGAGGSPALVRRRLEATPVQKKEKKDKERENEKEKSALARERNLKKRQSLPASIRPRISTGAELSTKSKARPTSPSTTWHRPASPCPSPGPGHTLPPKPPSPRGTTASPKGRIRRKEEAKESPSPSGPEDKNHSKSRTAEEKEPAAPASPAPSPVPSPTPAQPQKEQSSTQIPPDTAVPAVPTVPTFPTAPPTAAPSVTPSKPMAGTTDREEATRLLAEKRRQAREQREREEQERKLQAERDKRMREEQLAREAEARAEREAEARRREEQEAREKAQAEQEEQERLQKQKEEAEARSREEAERQRLEREKHFQKEEQERQERRKRLEEIMKRTRKSEAAETKKQDGKETMANNSGPDPVKAVETRPSGLQKDSMQKEELAPQEPQWSLPSKEMPGSLVNGLQPLPAHQENGFPAKGTAGDKSLGRAAEGLLPFAEADAFLKKAVVQPPQVTEVL", "length": 849 }, "evidence": [ { "id": "A0A8V0YPU7", "url": "https://omabrowser.org/oma/group/A0A8V0YPU7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0AB32T9H0-1", "protein_name": "MAP7 domain-containing protein 1a isoform X1", "gene_name": "map7d1a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEFNHIDTQSGLNQMTPSETHPPAVSETNQSDPCSEEVIPSSRTELGLDAGTPTKMDAAQKPSTPTQPDVIPKSPARSSGSLHPKKDGMKYDERQKQAKERREEKAKYLEQRSQTQAAKKSQWLEKEERARQVREQQLEERRRKLEEQRLKAERRRAELEDRQKQKLEKNKERYEAAIQRSGKKTWAEIRQQRWSWAGGLSGNSSQSQSRCSISAVNLPKHVDSVINKRLSKSSATLWNTPSRTRSLQLSPWESSIVDRLMTPTLSFLARSRSAASVLNNSRDAQSPLCPRSASASPLSVCAHRPHRCSERWRVTTSTPDITQRRRDSTPLRKDKKDKERENEKEKNSITKEKVLKKRQSMPSIKTRIESSPSPVFKLRSASPATPKARVSSPSPAVSPKPPAAQASPMTPKARPKRARTPARVETRTASPVAIDRVREPRRPATPEQPKILIFPPLRFSVFAPASSPVPSIVVSSVLDTPPVTSAPMVSVSASPVPEDSPLVSALPQVSSPAPSPGKPMAGTNNPEEATRILAEKRRQAREQREKEEEERREQLERERIQREERLVQEAEERKRREEEARLMAEQEKLREEARRLQEEEAALERAKIEQEENERLQKQKEEAETKAKEEAEKQRLEREKHFQKEEQERLERKKRLEEIMKRTRKTDAAEKKDSTSPAQVNGKDSEMNKAAADYQPNTALKQDGVNESLSVPVLNGIQTSKHENGLSAKGEASQFEEILQLSNHNNGREKSESDRPDEPIMAFESSESFLKKTGPLKPQHVAEVL", "length": 785 }, "evidence": [ { "id": "A0A8V0YPU7", "url": "https://omabrowser.org/oma/group/A0A8V0YPU7/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A2AJI0-1", "protein_name": "MAP7 domain-containing protein 1", "gene_name": "Map7d1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MESGPRVEPGPGAPAAVLARIPQEPRPSPEGDPSPPPPPTPMSALVPDTPPDTPPALKTATNPKQLPLEPGNPTGQISPQPAPPQEECPSSEAKSRGPTPTATGPREAKPSRRSSQPSPTTVPASDSPPAKQDVKKAGERHKLAKERREERAKYLAAKKAVWLEKEEKAKALREKQLQERRRRLEEQRLKAEQRRAALEERQRQKLEKNKERYEAAIQRSVKKTWAEIRQQRWSWAGALHHSSPGRKTSGSRCSVSAVNLPKHVDSIINKRLSKSSATLWNSPSRNRSLQLSAWESSIVDRLMTPTLSFLARSRSAVTLPRNGRDQGRGSGPGRRPTRARAGASLAPGPHPDRTHPSAAVPVCPRSASASPLTPCSAPRSAHRCTPSGERPERRKPGAGGSPALARRRLEATPVQKKEKKDKERENEKEKSALARERNLKKRQSLPASIRPRLSTGSELSPKSKARPSSPSTTWHRPASPCPSPGPGHALPPKPPSPRGTTASPKGRVRRKEEAKESPSPSGPEDKNHRKSRAAEEKEPAAPASPAPSPVPSPTPAQPQKEQSSTQIPAETAVPAVPAAPTAPPTAAPSVTPSKPMAGTTDREEATRLLAEKRRQAREQREREEQERKLQAERDKRMREEQLAREAEARAEREAEARRREEQEAREKAQAEQEEQERLQKQKEEAEARSREEAERQRQEREKHFQKEEQERQERRKRLEEIMKRTRKSEAAETKKQDAKETAANNSGPDPVKAVETRPSGLQKDSMQKEELAPQEPQWSLPSKEMPGSLVNGLQPLPAHQENGFSPKGTAGDKSLGRTAEGLLPFAEAEAFLKKAVVQPPQVTEVL", "length": 846 }, "evidence": [ { "id": "A0A8V0YPU7", "url": "https://omabrowser.org/oma/group/A0A8V0YPU7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q3KQU3-1", "protein_name": "MAP7 domain-containing protein 1", "gene_name": "MAP7D1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MESGPRAELGAGAPPAVVARTPPEPRPSPEGDPSPPPPPMSALVPDTPPDTPPAMKNATSSKQLPLEPESPSGQVGPRPAPPQEESPSSEAKSRGPTPPAMGPRDARPPRRSSQPSPTAVPASDSPPTKQEVKKAGERHKLAKERREERAKYLAAKKAVWLEKEEKAKALREKQLQERRRRLEEQRLKAEQRRAALEERQRQKLEKNKERYEAAIQRSVKKTWAEIRQQRWSWAGALHHSSPGHKTSGSRCSVSAVNLPKHVDSIINKRLSKSSATLWNSPSRNRSLQLSAWESSIVDRLMTPTLSFLARSRSAVTLPRNGRDQGRGCDPGRGPTWGRAGASLARGPQPDRTHPSAAVPVCPRSASASPLTPCSVTRSVHRCAPAGERGERRKPNAGGSPAPVRRRPEASPVQKKEKKDKERENEKEKSALARERSLKKRQSLPASPRARLSASTASELSPKSKARPSSPSTSWHRPASPCPSPGPGHTLPPKPPSPRGTTASPKGRVRRKEEAKESPSAAGPEDKSQSKRRASNEKESAAPASPAPSPAPSPTPAPPQKEQPPAETPTDAAVLTSPPAPAPPVTPSKPMAGTTDREEATRLLAEKRRQAREQREREEQERRLQAERDKRMREEQLAREAEARAEREAEARRREEQEAREKAQAEQEEQERLQKQKEEAEARSREEAERQRLEREKHFQQQEQERQERRKRLEEIMKRTRKSEVSETKQKQDSKEANANGSSPEPVKAVEARSPGLQKEAVQKEEPIPQEPQWSLPSKELPASLVNGLQPLPAHQENGFSTNGPSGDKSLSRTPETLLPFAEAEAFLKKAVVQSPQVTEVL", "length": 841 }, "evidence": [ { "id": "A0A8V0YPU7", "url": "https://omabrowser.org/oma/group/A0A8V0YPU7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPU7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPU7" } ], "pmid": "" }, { "name": "microtubule cytoskeleton", "id": "GO:0015630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015630", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPU7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPU7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "microtubule cytoskeleton organization", "id": "GO:0000226", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000226", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPU7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPU7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 410, "end_pos": 412, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 53, 59, 73, 239 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 410, "end_pos": 412 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 4 }, { "field": "total_sites", "count": 4 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 4 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 4 }, { "field": "exact_o_linked_sites", "count": 4 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 4 }, { "field": "total_sites", "count": 4 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 4 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 4 }, { "field": "exact_o_linked_sites", "count": 4 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YPV7-1", "uniprot_ac": "A0A8V0YPV7", "uniprot_id": "A0A8V0YPV7_CHICK", "mass": { "chemical_mass": 30598.0, "monoisotopic_mass": 30598.0 }, "refseq": {}, "gene_names": [ { "name": "RWDD1", "type": "recommended", "evidence": [ { "id": "A0A8V0YPV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPV7" } ] } ], "protein_names": [ { "name": "RWD domain-containing protein 1", "type": "recommended", "evidence": [ { "id": "A0A8V0YPV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPV7/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Protects DRG2 from proteolytic degradation. May function as a coactivator of the AR/androgen receptor transcription factor during development.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPU8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPU8#function" }, { "database": "UniProtKB", "id": "ARBA00094243", "url": "https://www.uniprot.org/uniprotkb/ARBA00094243#function" }, { "database": "UniProtKB", "id": "A0A8V0YPV2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPV2#function" }, { "database": "UniProtKB", "id": "A0A8V0YPV7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPV7#function" }, { "database": "UniProtKB", "id": "A0A8V0YWL7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YWL7#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPV7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPV7" } ], "common_name": "Chicken", 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"url": "https://www.ebi.ac.uk/interpro/entry/IPR032378", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040213", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040213", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YPU8", "url": "https://www.orthodb.org/?gene=A0A8V0YPU8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YPV2", "url": "https://www.orthodb.org/?gene=A0A8V0YPV2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YPV7", "url": "https://www.orthodb.org/?gene=A0A8V0YPV7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YWL7", "url": "https://www.orthodb.org/?gene=A0A8V0YWL7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12292", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12292", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05773", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05773", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16543", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16543", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-9629569", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9629569", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YPU8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPU8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YPU8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPU8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YPV2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPV2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YPV2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPV2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YPV7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPV7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YPV7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPV7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YWL7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YWL7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YWL7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YWL7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPAGAAHAWGEAGRGAAGGVRGSWPLAAMTDYSEEQRNELEALESIYPDSFTVLSEKPTTFTITVTSEAGENDENVQTTLKFTYREKYPDETPLYEIVSQENLEDNDVTGIINLLEQQAEENLGMVMIFTLVSAVQEKLNEIVDQIKTRREEEKKQKEREAEEEEKQRFHGTPVTIENFLNWKAKFDAELLEIKRKKMKEEEQAGKNKLSGKQLFEMDHNLDTSDIQFLEEAGNSVEVDESLFQEMDDLELEDEEDDPDYNPVNLDSD", "length": 268, "header": "tr|A0A8V0YPV7-1|A0A8V0YPV7_CHICK Isoform 1 of RWD domain-containing protein 1 OS=Gallus gallus OX=9031 GN=RWDD1 PE=1 SV=1 CANONICAL=A0A8V0YPV7-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YPU8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPV7/entry#A0A8V0YPU8-1", "sequence": { "sequence": "MTDYSEEQRNELEALESIYPDSFTVLSEKPTTFTITVTSEAGENDENVQTTLKFTYREKYPDETPLYEIVSQENLEDNDVTGIINLLEQQAEENLGMHPLKRRDSKQEGKMAW", "length": 113, "header": "tr|A0A8V0YPU8-1|A0A8V0YPV7_CHICK Computationally mapped isoform of RWD domain-containing protein 1 OS=Gallus gallus OX=9031 GN=RWDD1 PE=1 SV=1 CANONICAL=A0A8V0YPV7-1" }, "locus": { "chromosome": "3", "start_pos": 63512385, "end_pos": 63503332, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010035648.1", "url": "https://www.ensembl.org/id/ENSGALT00010035648.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020689.1", "url": "https://www.ensembl.org/id/ENSGALP00010020689.1" } ] } }, { "isoform_ac": "A0A8V0YPV2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPV7/entry#A0A8V0YPV2-1", "sequence": { "sequence": "MTDYSEEQRNELEALESIYPDSFTVLSEKPTTFTITVTSEAGENDETLGTCLNCSYWHQDDVQTTLKFTYREKYPDETPLYEIVSQENLEDNDVTGIINLLEQQAEENLGMVMIFTLVSAVQEKLNEIVDQIKTRREEEKKQKEREAEEEEKQRFHGTPVTIENFLNWKAKFDAELLEIKRKKMKEEEQAGKNKLSGKQLFEMDHNLDTSDIQFLEEAGNSVEVDESLFQEMDDLELEDEEDDPDYNPVNLDSD", "length": 254, "header": "tr|A0A8V0YPV2-1|A0A8V0YPV2_CHICK Computationally mapped isoform of RWD domain-containing protein 1 OS=Gallus gallus OX=9031 GN=RWDD1 PE=1 SV=1 CANONICAL=A0A8V0YPV7-1" }, "locus": { "chromosome": "3", "start_pos": 63512385, "end_pos": 63503631, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010035640.1", "url": "https://www.ensembl.org/id/ENSGALT00010035640.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020687.1", "url": "https://www.ensembl.org/id/ENSGALP00010020687.1" } ] } }, { "isoform_ac": "A0A8V0YPV7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPV7/entry#A0A8V0YPV7-1", "sequence": { "sequence": "MPAGAAHAWGEAGRGAAGGVRGSWPLAAMTDYSEEQRNELEALESIYPDSFTVLSEKPTTFTITVTSEAGENDENVQTTLKFTYREKYPDETPLYEIVSQENLEDNDVTGIINLLEQQAEENLGMVMIFTLVSAVQEKLNEIVDQIKTRREEEKKQKEREAEEEEKQRFHGTPVTIENFLNWKAKFDAELLEIKRKKMKEEEQAGKNKLSGKQLFEMDHNLDTSDIQFLEEAGNSVEVDESLFQEMDDLELEDEEDDPDYNPVNLDSD", "length": 268, "header": "tr|A0A8V0YPV7-1|A0A8V0YPV7_CHICK Isoform 1 of RWD domain-containing protein 1 OS=Gallus gallus OX=9031 GN=RWDD1 PE=1 SV=1 CANONICAL=A0A8V0YPV7-1" }, "locus": { "chromosome": "3", "start_pos": 63512469, "end_pos": 63503631, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010035654.1", "url": "https://www.ensembl.org/id/ENSGALT00010035654.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020692.1", "url": "https://www.ensembl.org/id/ENSGALP00010020692.1" } ] } }, { "isoform_ac": "A0A8V0YWL7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPV7/entry#A0A8V0YWL7-1", "sequence": { "sequence": "MPAGAAHAWGEAGRGAAGGVRGSWPLAAMTDYSEEQRNELEALESIYPDSFTVLSEKPTTFTITVTSEAGENDENVQTTLKFTYREKYPDETPLYEIVSQENLEDNDVTGIINLLEQQHPLKRRDSKQEGKMAW", "length": 134, "header": "tr|A0A8V0YWL7-1|A0A8V0YWL7_CHICK Computationally mapped isoform of RWD domain-containing protein 1 OS=Gallus gallus OX=9031 GN=RWDD1 PE=3 SV=1 CANONICAL=A0A8V0YPV7-1" }, "locus": { "chromosome": "3", "start_pos": 63512469, "end_pos": 63503332, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010035653.1", "url": "https://www.ensembl.org/id/ENSGALT00010035653.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020691.1", "url": "https://www.ensembl.org/id/ENSGALP00010020691.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-9629569", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9629569", "resource": "Reactome", "description": "Protein hydroxylation" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPV7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPV7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "transcription coactivator activity", "id": "GO:0003713", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003713", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPV7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPV7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "androgen receptor signaling pathway", "id": "GO:0030521", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030521", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPV7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPV7" } ], "pmid": "" }, { "name": "cytoplasmic translation", "id": "GO:0002181", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002181", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPV7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPV7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YPV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPV7" }, { "id": "PS50908", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50908" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RWD", "eco_id": "ECO_0000259", "start_pos": 38, "end_pos": 142, "start_aa": "Asn", "end_aa": "Ile", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YPV4-1", "uniprot_ac": "A0A8V0YPV4", "uniprot_id": "A0A8V0YPV4_CHICK", "mass": { "chemical_mass": 39705.0, "monoisotopic_mass": 39705.0 }, "refseq": { "ac": "XP_004937825", "name": "testis-expressed protein 33 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004937825" }, "gene_names": [ { "name": "TEX33", "type": "recommended", "evidence": [ { "id": "A0A8V0YPV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPV4" } ] }, { "name": "TEX33", "type": "synonym", "evidence": [ { "id": "XP_004937825", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004937825" } ] } ], "protein_names": [ { "name": "Testis-expressed protein 33", "type": "recommended", "evidence": [ { "id": "A0A8V0YPV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPV4/entry#names_and_taxonomy" } ] }, { "name": "testis-expressed protein 33 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_004937825", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004937825" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_004937825.3. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004937825", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004937825" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPV4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPV4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TEX33", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPV4", "locus": {} } ], "crossref": [ { "id": "A0A8V0YPV4", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YPV4", "database": "AlphaFoldDB", "categories": [] }, { "id": "418050", "url": "https://www.ncbi.nlm.nih.gov/gene/418050", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR029234", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029234", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:418050", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418050", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MWQACGA", "url": "https://omabrowser.org/oma/group/MWQACGA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YPV4", "url": "https://www.orthodb.org/?gene=A0A8V0YPV4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31702", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31702", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31702:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31702:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15400", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15400", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_004937825", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004937825", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YPV4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPV4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YPV4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPV4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDQVRKAMTEVPASSFDVARSDSVHTNNASVEPEERKTKHFPAGLSPSRQRTSQKTPSRVSCKISKSSAARGTTKNSTHTKSKASPSVKGIQNKRQSKQHLQAKTSHMQNHNSRRFEEEGEDISATKGPRARLEPRSRNSISCLSAASRQREAENTKSMPNDKESVAGQQQTPDSKMPGSLWKTTKASCENAKETNESLTSTAPDMKAEWEVPLEKKNSLSRYNRKDKFASTDELTSNEEERRSLCMTALIIGQKRLSDRSDMLKKQLESFGDFNELGFNLRSNIFQGGPLESRSLMKDSYTPDVIQKVTRDPRNWHGRRIDELGRWHQKNALNLNLQKALEDKYGKKKAKP", "length": 352, "header": "tr|A0A8V0YPV4-1|A0A8V0YPV4_CHICK Isoform 1 of Testis-expressed protein 33 OS=Gallus gallus OX=9031 GN=TEX33 PE=4 SV=1 CANONICAL=A0A8V0YPV4-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YPV4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPV4/entry#A0A8V0YPV4-1", "sequence": { "sequence": "MDQVRKAMTEVPASSFDVARSDSVHTNNASVEPEERKTKHFPAGLSPSRQRTSQKTPSRVSCKISKSSAARGTTKNSTHTKSKASPSVKGIQNKRQSKQHLQAKTSHMQNHNSRRFEEEGEDISATKGPRARLEPRSRNSISCLSAASRQREAENTKSMPNDKESVAGQQQTPDSKMPGSLWKTTKASCENAKETNESLTSTAPDMKAEWEVPLEKKNSLSRYNRKDKFASTDELTSNEEERRSLCMTALIIGQKRLSDRSDMLKKQLESFGDFNELGFNLRSNIFQGGPLESRSLMKDSYTPDVIQKVTRDPRNWHGRRIDELGRWHQKNALNLNLQKALEDKYGKKKAKP", "length": 352, "header": "tr|A0A8V0YPV4-1|A0A8V0YPV4_CHICK Isoform 1 of Testis-expressed protein 33 OS=Gallus gallus OX=9031 GN=TEX33 PE=4 SV=1 CANONICAL=A0A8V0YPV4-1" }, "locus": { "chromosome": "1", "start_pos": 51564587, "end_pos": 51559728, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010035657.1", "url": "https://www.ensembl.org/id/ENSGALT00010035657.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020694.1", "url": "https://www.ensembl.org/id/ENSGALP00010020694.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:418050", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418050", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 196, "end_pos": 198, "annotation": "n_glycosylation_sequon" }, { "start_pos": 28, "end_pos": 30, "annotation": "n_glycosylation_sequon" }, { "start_pos": 76, "end_pos": 78, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 196, "end_pos": 198 }, { "start_pos": 28, "end_pos": 30 }, { "start_pos": 76, "end_pos": 78 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YPW4-1", "uniprot_ac": "A0A8V0YPW4", "uniprot_id": "A0A8V0YPW4_CHICK", "mass": { "chemical_mass": 28689.0, "monoisotopic_mass": 28689.0 }, "refseq": {}, "gene_names": [ { "name": "UBE2J2", "type": "recommended", "evidence": [ { "id": "A0A8V0YPW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPW4" } ] } ], "protein_names": [ { "name": "Ubiquitin-conjugating enzyme E2 J2", "type": "recommended", "evidence": [ { "id": "A0A8V0YPW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPW4/entry#names_and_taxonomy" } ] }, { "name": "2.3.2.23", "type": "synonym", "evidence": [ { "id": "A0A8V0YPW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPW4/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Catalyzes the covalent attachment of ubiquitin to other proteins. Seems to function in the selective degradation of misfolded membrane proteins from the endoplasmic reticulum (ERAD). In cooperation with the GATOR2 complex, catalyzes 'Lys-6'-linked ubiquitination of NPRL2.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YY85", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YY85#function" }, { "database": "UniProtKB", "id": "ARBA00054775", "url": "https://www.uniprot.org/uniprotkb/ARBA00054775#function" }, { "database": "UniProtKB", "id": "A0A8V0YPW4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPW4#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPW4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPW4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "UBE2J2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPW4", "locus": { "chromosome": "21", "start_pos": 2467881, "end_pos": 2460165, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010016541", "url": "https://www.ensembl.org/id/ENSGALG00010016541" } ] } } ], "crossref": [ { "id": "A0A8V0YPW4", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YPW4", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd23799", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd23799", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000608", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000608", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016135", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016135", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050113", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050113", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YPW4", "url": "https://www.orthodb.org/?gene=A0A8V0YPW4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YY85", "url": "https://www.orthodb.org/?gene=A0A8V0YY85", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24067", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24067", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00179", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00179", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-9609523", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9609523", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-983168", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983168", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YPW4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPW4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YPW4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPW4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YY85", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YY85", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YY85-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YY85-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSNNSNKRAPTTATQRLKQDYLRIKKDPVPYICAEPLPSNILEWHYVVRGPETTPYEGGYYHGKLIFPREFPFKPPSIYMITPNGRFKCNTRLCLSITDFHPDTWNPAWSVSTILTGLLSFMVEKGPTLGSIETSEFAKRQLAAQSLAFNLKDKVFCELFPEVEIKQKQKAQEELNSRPPSLPLPDVVPDGEAHYGQNGIPLLNGHVPLAPANHPGLQQANRNHGLLGGALANLFVIVGFAAFAYTVKYVLRSIAQE", "length": 257, "header": "tr|A0A8V0YPW4-1|A0A8V0YPW4_CHICK Isoform 1 of Ubiquitin-conjugating enzyme E2 J2 OS=Gallus gallus OX=9031 GN=UBE2J2 PE=4 SV=1 CANONICAL=A0A8V0YPW4-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YPW4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPW4/entry#A0A8V0YPW4-1", "sequence": { "sequence": "MSNNSNKRAPTTATQRLKQDYLRIKKDPVPYICAEPLPSNILEWHYVVRGPETTPYEGGYYHGKLIFPREFPFKPPSIYMITPNGRFKCNTRLCLSITDFHPDTWNPAWSVSTILTGLLSFMVEKGPTLGSIETSEFAKRQLAAQSLAFNLKDKVFCELFPEVEIKQKQKAQEELNSRPPSLPLPDVVPDGEAHYGQNGIPLLNGHVPLAPANHPGLQQANRNHGLLGGALANLFVIVGFAAFAYTVKYVLRSIAQE", "length": 257, "header": "tr|A0A8V0YPW4-1|A0A8V0YPW4_CHICK Isoform 1 of Ubiquitin-conjugating enzyme E2 J2 OS=Gallus gallus OX=9031 GN=UBE2J2 PE=4 SV=1 CANONICAL=A0A8V0YPW4-1" }, "locus": { "chromosome": "21", "start_pos": 2464805, "end_pos": 2461982, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010039836.1", "url": "https://www.ensembl.org/id/ENSGALT00010039836.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023053.1", "url": "https://www.ensembl.org/id/ENSGALP00010023053.1" } ] } }, { "isoform_ac": "A0A8V0YY85-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPW4/entry#A0A8V0YY85-1", "sequence": { "sequence": "MSNNSNKRAPTTATQRLKQDYLRIKKDPVPYICAEPLPSNILEWHYVVRGPETTPYEGGYYHGKLIFPREFPFKPPSIYMITPNGRFKCNTRLCLSITDFHPDTWNPAWSVSTILTGLLSFMVEKGPTLGSIETSEFAKRQLAAQSLAFNLKDKVFCELFPEVVEEIKQKQKAQEELNSRPPSLPLPDVVPDGEAHYGQNGIPLLNGHVPLAPANRNHGLLGGALANLFVIVGFAAFAYTVKYVLRSIAQE", "length": 251, "header": "tr|A0A8V0YY85-1|A0A8V0YY85_CHICK Computationally mapped isoform of Ubiquitin-conjugating enzyme E2 J2 OS=Gallus gallus OX=9031 GN=UBE2J2 PE=4 SV=1 CANONICAL=A0A8V0YPW4-1" }, "locus": { "chromosome": "21", "start_pos": 2464805, "end_pos": 2461982, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010039834.1", "url": "https://www.ensembl.org/id/ENSGALT00010039834.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023051.1", "url": "https://www.ensembl.org/id/ENSGALP00010023051.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "R-GGA-9609523", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9609523", "resource": "Reactome", "description": "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" }, { "id": "R-GGA-983168", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983168", "resource": "Reactome", "description": "Antigen processing: Ubiquitination & Proteasome degradation" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPW4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPW4" } ], "pmid": "" }, { "name": "ubiquitin protein ligase binding", "id": "GO:0031625", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031625", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPW4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPW4" } ], "pmid": "" }, { "name": "ubiquitin conjugating enzyme activity", "id": "GO:0061631", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061631", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPW4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPW4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPW4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPW4" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPW4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPW4" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPW4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPW4" } ], "pmid": "" }, { "name": "ubiquitin ligase complex", "id": "GO:0000151", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000151", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPW4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPW4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "protein polyubiquitination", "id": "GO:0000209", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000209", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPW4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPW4" } ], "pmid": "" }, { "name": "ubiquitin-dependent protein catabolic process", "id": "GO:0006511", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006511", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPW4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPW4" } ], "pmid": "" }, { "name": "ERAD pathway", "id": "GO:0036503", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036503", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPW4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPW4" } ], "pmid": "" }, { "name": "protein K6-linked ubiquitination", "id": "GO:0085020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0085020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPW4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPW4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 3, "end_pos": 5, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-GGA-9609921", "name": "SGTA binds Tail-anchored protein", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YPW4-1", "A0A8V0YK13-1" ], "evidence": [ { "id": "R-GGA-9609921", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9609921" } ] }, { "id": "R-GGA-983140", "name": "Transfer of Ub from E2 to substrate and release of E2", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0X324-1", "A0A8V0XEM6-1", "A0A8V0XJC4-1", "A0A8V0XQR1-1", "A0A8V1AC19-1", "A0A8V1AC55-1", "A0A8V1AKB8-1", "A0A8V1ALH0-1", "F1NL19-1", "F1NRC6-1", "F1NTZ8-1", "A0A8V0YHL7-1", "A0A8V0YPW4-1", "A0A8V0YRM6-1", "A0A8V0YV22-1", "A0A8V0YVP3-1", "A0A8V0Z2L5-1", "F1NL77-1", "E1C982-1", "A0A3Q2UC96-1", "Q5ZKX6-1", "Z4YJC3-1", "A0A8V0XQU7-1", "A0A8V0Y5C9-1", "A0A8V1AL09-1", "A0A8V1AML5-1", "A0A8V1AP69-1", "F1NVY8-1", "R4GIV8-1", "A0A8V0ZJ49-1", "A0A8V0ZJV9-1", "A0A8V0ZL18-1", "A0A8V0ZM17-1", "A0A8V0ZSH4-1", "A0A8V0ZVX3-1", "A0A8V0ZW26-1", "A0A8V1A0Z6-1", "A0A8V0ZZH3-1", "A0A8V1A052-1", "A0A8V1A0X2-1", "A0A8V1A1I4-1", "A0A8V1A2W7-1", "A0A8V1A5P4-1", "A0A8V1A7T1-1", "A0A8V0XTY5-1", "A0A8V0Y5B5-1", "A0A8V0YL05-1", "A0A8V0Z082-1", "A0A8V0ZS27-1", "A0A8V1A9M0-1", "E1BZ35-1", "E1C3Q9-1", "F1NC08-1", "F1P2G0-1", "A0A8V0YY10-1", "A0A8V0YYC5-1", "A0A8V0Z1W7-1", "A0A8V0Z4C8-1", "A0A8V0Z596-1", "A0A1D5P284-1", "A0A8V0ZF21-1", "A0A3Q2U2G8-1", "A0A8V1A4H7-1", "A0A8V1A1N8-1", "A0A8V1A233-1", "A0A8V1A7P9-1", "A0A8V1ACU3-1", "A0A8V0ZSA3-1", "E1C656-1", "A0A8V0Y0Q7-1", "A0A8V0Y059-1", "A0A8V0Y5C7-1", "A0A8V0YCS7-1", "A0A8V0YDQ1-1", "A0A8V0YFD9-1", "A0A8V0YGF4-1", "A0A8V0YJK8-1", "A0A8V0YLY7-1", "A0A1D5NVE2-1", "A0A8V0ZKK3-1", "A0A8V0ZKQ3-1" ], "evidence": [ { "id": "R-GGA-983140", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983140" } ] }, { "id": "R-GGA-983152", "name": "Transfer of ubiquitin from E1 to E2", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0X324-1", "A0A8V0XQR1-1", "A0A8V1AC19-1", "F1NL19-1", "A0A8V0YPW4-1", "Q5ZKX6-1", "R4GIV8-1", "A0A8V0ZBK2-1", "A0A8V1A052-1", "A0A8V1A1I4-1", "A0A8V1A5P4-1", "A0A8V0Z082-1", "A0A8V0YY10-1", "A0A8V0Z1W7-1", "A0A8V0XNP1-1", "A0A8V1A4H7-1", "A0A8V1ACU3-1", "A0A8V0Y059-1", "A0A8V0YFD9-1", "A0A1D5NVE2-1" ], "evidence": [ { "id": "R-GGA-983152", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983152" } ] }, { "id": "R-GGA-983156", "name": "Polyubiquitination of substrate", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0X324-1", "A0A8V0XEM6-1", "A0A8V0XJC4-1", "A0A8V0XQR1-1", "A0A8V1AC19-1", "A0A8V1AC55-1", "A0A8V1AKB8-1", "A0A8V1ALH0-1", "F1NL19-1", "F1NRC6-1", "F1NTZ8-1", "A0A8V0YHL7-1", "A0A8V0YPW4-1", "A0A8V0YRM6-1", "A0A8V0YV22-1", "A0A8V0YVP3-1", "A0A8V0Z2L5-1", "F1NL77-1", "E1C982-1", "A0A3Q2UC96-1", "Q5ZKX6-1", "Z4YJC3-1", "A0A8V0XQU7-1", "A0A8V0Y5C9-1", "A0A8V1AL09-1", "A0A8V1AML5-1", "A0A8V1AP69-1", "F1NVY8-1", "R4GIV8-1", "A0A8V0ZJ49-1", "A0A8V0ZJV9-1", "A0A8V0ZL18-1", "A0A8V0ZM17-1", "A0A8V0ZSH4-1", "A0A8V0ZVX3-1", "A0A8V0ZW26-1", "A0A8V1A0Z6-1", "A0A8V0ZZH3-1", "A0A8V1A052-1", "A0A8V1A0X2-1", "A0A8V1A1I4-1", "A0A8V1A2W7-1", "A0A8V1A5P4-1", "A0A8V1A7T1-1", "A0A8V0XTY5-1", "A0A8V0Y5B5-1", "A0A8V0YL05-1", "A0A8V0Z082-1", "A0A8V0ZS27-1", "A0A8V1A9M0-1", "E1BZ35-1", "E1C3Q9-1", "F1NC08-1", "F1P2G0-1", "A0A8V0YY10-1", "A0A8V0YYC5-1", "A0A8V0Z1W7-1", "A0A8V0Z4C8-1", "A0A8V0Z596-1", "A0A1D5P284-1", "A0A8V0ZF21-1", "A0A3Q2U2G8-1", "A0A8V1A4H7-1", "A0A8V1A1N8-1", "A0A8V1A233-1", "A0A8V1A7P9-1", "A0A8V1ACU3-1", "A0A8V0ZSA3-1", "E1C656-1", "A0A8V0Y0Q7-1", "A0A8V0Y059-1", "A0A8V0Y5C7-1", "A0A8V0YCS7-1", "A0A8V0YDQ1-1", "A0A8V0YFD9-1", "A0A8V0YGF4-1", "A0A8V0YJK8-1", "A0A8V0YLY7-1", "A0A1D5NVE2-1", "A0A8V0ZKK3-1", "A0A8V0ZKQ3-1" ], "evidence": [ { "id": "R-GGA-983156", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983156" } ] }, { "id": "R-GGA-983157", "name": "Interaction of E3 with substrate and E2-Ub complex", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0X324-1", "A0A8V0XEM6-1", "A0A8V0XJC4-1", "A0A8V0XQR1-1", "A0A8V1AC19-1", "A0A8V1AC55-1", "A0A8V1AKB8-1", "A0A8V1ALH0-1", "F1NL19-1", "F1NRC6-1", "F1NTZ8-1", "A0A8V0YHL7-1", "A0A8V0YPW4-1", "A0A8V0YRM6-1", "A0A8V0YV22-1", "A0A8V0YVP3-1", "A0A8V0Z2L5-1", "F1NL77-1", "E1C982-1", "A0A3Q2UC96-1", "Q5ZKX6-1", "Z4YJC3-1", "A0A8V0XQU7-1", "A0A8V0Y5C9-1", "A0A8V1AL09-1", "A0A8V1AML5-1", "A0A8V1AP69-1", "F1NVY8-1", "R4GIV8-1", "A0A8V0ZJ49-1", "A0A8V0ZJV9-1", "A0A8V0ZL18-1", "A0A8V0ZM17-1", "A0A8V0ZSH4-1", "A0A8V0ZVX3-1", "A0A8V0ZW26-1", "A0A8V1A0Z6-1", "A0A8V0ZZH3-1", "A0A8V1A052-1", "A0A8V1A0X2-1", "A0A8V1A1I4-1", "A0A8V1A2W7-1", "A0A8V1A5P4-1", "A0A8V1A7T1-1", "A0A8V0XTY5-1", "A0A8V0Y5B5-1", "A0A8V0YL05-1", "A0A8V0Z082-1", "A0A8V0ZS27-1", "A0A8V1A9M0-1", "E1BZ35-1", "E1C3Q9-1", "F1NC08-1", "F1P2G0-1", "A0A8V0YY10-1", "A0A8V0YYC5-1", "A0A8V0Z1W7-1", "A0A8V0Z4C8-1", "A0A8V0Z596-1", "A0A1D5P284-1", "A0A8V0ZF21-1", "A0A3Q2U2G8-1", "A0A8V1A4H7-1", "A0A8V1A1N8-1", "A0A8V1A233-1", "A0A8V1A7P9-1", "A0A8V1ACU3-1", "A0A8V0ZSA3-1", "E1C656-1", "A0A8V0Y0Q7-1", "A0A8V0Y059-1", "A0A8V0Y5C7-1", "A0A8V0YCS7-1", "A0A8V0YDQ1-1", "A0A8V0YFD9-1", "A0A8V0YGF4-1", "A0A8V0YJK8-1", "A0A8V0YLY7-1", "A0A1D5NVE2-1", "A0A8V0ZKK3-1", "A0A8V0ZKQ3-1" ], "evidence": [ { "id": "R-GGA-983157", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983157" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A1D5NVE2", "gene_name": "UBE2Q1", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A1D5NVE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NVE2" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A1D5NVE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NVE2" } ] } ] }, { "uniprot_ac": "A0A1D5P284", "gene_name": "UBR2", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A1D5P284", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P284" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A1D5P284", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P284" } ] } ] }, { "uniprot_ac": "A0A3Q2U2G8", "gene_name": "TRIM9", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A3Q2U2G8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U2G8" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A3Q2U2G8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U2G8" } ] } ] }, { "uniprot_ac": "A0A3Q2UC96", "gene_name": "NEDD4L", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A3Q2UC96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UC96" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A3Q2UC96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UC96" } ] } ] }, { "uniprot_ac": "A0A8V0X324", "gene_name": "UBE2E1", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V0X324", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X324" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V0X324", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X324" } ] } ] }, { "uniprot_ac": "A0A8V0XEM6", "gene_name": "HERC2", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0XEM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEM6" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0XEM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEM6" } ] } ] }, { "uniprot_ac": "A0A8V0XJC4", "gene_name": "UBE3D", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0XJC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XJC4" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0XJC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XJC4" } ] } ] }, { "uniprot_ac": "A0A8V0XNP1", "gene_name": "UBA6", "activity": [ { "ec_number": "6.2.1.45", "activity": "ATP + ubiquitin + [E1 ubiquitin-activating enzyme]-L-cysteine = AMP + diphosphate + S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V0XNP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNP1" } ] }, { "ec_number": "6.2.1.45", "activity": "", "evidence": [ { "id": "A0A8V0XNP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNP1" } ] } ] }, { "uniprot_ac": "A0A8V0XQR1", "gene_name": "UBE2H", "activity": [ { "ec_number": "2.3.2.24", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E1 ubiquitin-activating enzyme]-L-cysteine + N(6)-monoubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0XQR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQR1" } ] }, { "ec_number": "2.3.2.24", "activity": "", "evidence": [ { "id": "A0A8V0XQR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQR1" } ] } ] }, { "uniprot_ac": "A0A8V0XQU7", "gene_name": "RNF6", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0XQU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQU7" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0XQU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQU7" } ] } ] }, { "uniprot_ac": "A0A8V0XTY5", "gene_name": "SH3RF1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0XTY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XTY5" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0XTY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XTY5" } ] } ] }, { "uniprot_ac": "A0A8V0Y059", "gene_name": "UBE2D1", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V0Y059", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y059" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V0Y059", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y059" } ] } ] }, { "uniprot_ac": "A0A8V0Y0Q7", "gene_name": "RNF144B", "activity": [ { "ec_number": "2.3.2.31", "activity": "[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-N(6)-ubiquitinyl-L-lysine.", "evidence": [ { "id": "A0A8V0Y0Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y0Q7" } ] }, { "ec_number": "2.3.2.31", "activity": "", "evidence": [ { "id": "A0A8V0Y0Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y0Q7" } ] } ] }, { "uniprot_ac": "A0A8V0Y5B5", "gene_name": "LTN1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0Y5B5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5B5" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0Y5B5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5B5" } ] } ] }, { "uniprot_ac": "A0A8V0Y5C7", "gene_name": "CBLL1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0Y5C7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5C7" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0Y5C7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5C7" } ] } ] }, { "uniprot_ac": "A0A8V0Y5C9", "gene_name": "HERC3", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0Y5C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5C9" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0Y5C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5C9" } ] } ] }, { "uniprot_ac": "A0A8V0YCS7", "gene_name": "RNF19A", "activity": [ { "ec_number": "2.3.2.31", "activity": "[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-N(6)-ubiquitinyl-L-lysine.", "evidence": [ { "id": "A0A8V0YCS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCS7" } ] }, { "ec_number": "2.3.2.31", "activity": "", "evidence": [ { "id": "A0A8V0YCS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCS7" } ] } ] }, { "uniprot_ac": "A0A8V0YDQ1", "gene_name": "WWP1", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YDQ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDQ1" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0YDQ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDQ1" } ] } ] }, { "uniprot_ac": "A0A8V0YFD9", "gene_name": "UBE2D2", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V0YFD9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFD9" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V0YFD9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFD9" } ] } ] }, { "uniprot_ac": "A0A8V0YGF4", "gene_name": "MYLIP", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YGF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGF4" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0YGF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGF4" } ] } ] }, { "uniprot_ac": "A0A8V0YHL7", "gene_name": "RNF114", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YHL7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHL7" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0YHL7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHL7" } ] } ] }, { "uniprot_ac": "A0A8V0YJK8", "gene_name": "RNF14", "activity": [ { "ec_number": "2.3.2.31", "activity": "[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-N(6)-ubiquitinyl-L-lysine.", "evidence": [ { "id": "A0A8V0YJK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJK8" } ] }, { "ec_number": "2.3.2.31", "activity": "", "evidence": [ { "id": "A0A8V0YJK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJK8" } ] } ] }, { "uniprot_ac": "A0A8V0YK13", "gene_name": "HMOX1", "activity": [ { "ec_number": "1.14.14.18", "activity": "heme b + 3 reduced [NADPH--hemoprotein reductase] + 3 O2 = biliverdin IXalpha + CO + Fe(2+) + 3 oxidized [NADPH--hemoprotein reductase] + 3 H2O + H(+).", "evidence": [ { "id": "A0A8V0YK13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK13" } ] }, { "ec_number": "1.14.14.18", "activity": "", "evidence": [ { "id": "A0A8V0YK13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK13" } ] } ] }, { "uniprot_ac": "A0A8V0YL05", "gene_name": "UBE3A", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YL05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL05" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0YL05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL05" } ] } ] }, { "uniprot_ac": "A0A8V0YLY7", "gene_name": "MKRN4P", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YLY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLY7" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0YLY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLY7" } ] } ] }, { "uniprot_ac": "A0A8V0YPW4", "gene_name": "UBE2J2", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V0YPW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPW4" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V0YPW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPW4" } ] } ] }, { "uniprot_ac": "A0A8V0YRM6", "gene_name": "RNF130", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YRM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRM6" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0YRM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRM6" } ] } ] }, { "uniprot_ac": "A0A8V0YV22", "gene_name": "RNF4", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YV22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YV22" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0YV22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YV22" } ] } ] }, { "uniprot_ac": "A0A8V0YVP3", "gene_name": "RBBP6", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YVP3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YVP3" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0YVP3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YVP3" } ] } ] }, { "uniprot_ac": "A0A8V0YY10", "gene_name": "UBE2D3", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V0YY10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YY10" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V0YY10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YY10" } ] } ] }, { "uniprot_ac": "A0A8V0YYC5", "gene_name": "ZNRF2", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YYC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYC5" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0YYC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYC5" } ] } ] }, { "uniprot_ac": "A0A8V0Z082", "gene_name": "UBE2B", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V0Z082", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z082" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V0Z082", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z082" } ] } ] }, { "uniprot_ac": "A0A8V0Z1W7", "gene_name": "UBE2K", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V0Z1W7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1W7" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V0Z1W7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1W7" } ] } ] }, { "uniprot_ac": "A0A8V0Z2L5", "gene_name": "TRIM63", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0Z2L5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2L5" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0Z2L5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2L5" } ] } ] }, { "uniprot_ac": "A0A8V0Z4C8", "gene_name": "MGRN1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0Z4C8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4C8" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0Z4C8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4C8" } ] } ] }, { "uniprot_ac": "A0A8V0Z596", "gene_name": "STUB1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0Z596", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z596" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0Z596", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z596" } ] } ] }, { "uniprot_ac": "A0A8V0ZBK2", "gene_name": "UBA3", "activity": [ { "ec_number": "6.2.1.64", "activity": "ATP + [NEDD8 protein] + [E1 NEDD8-activating enzyme]-L-cysteine = AMP + diphosphate + [E1 NEDD8-activating enzyme]-S-[NEDD8 protein]-yl-L-cysteine.", "evidence": [ { "id": "A0A8V0ZBK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBK2" } ] }, { "ec_number": "6.2.1.64", "activity": "", "evidence": [ { "id": "A0A8V0ZBK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBK2" } ] } ] }, { "uniprot_ac": "A0A8V0ZF21", "gene_name": "DTX3L", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZF21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF21" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0ZF21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF21" } ] } ] }, { "uniprot_ac": "A0A8V0ZJ49", "gene_name": "SMURF1", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZJ49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ49" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0ZJ49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ49" } ] } ] }, { "uniprot_ac": "A0A8V0ZJV9", "gene_name": "MIB2", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZJV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJV9" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0ZJV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJV9" } ] } ] }, { "uniprot_ac": "A0A8V0ZKK3", "gene_name": "UBE3B", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZKK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKK3" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0ZKK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKK3" } ] } ] }, { "uniprot_ac": "A0A8V0ZKQ3", "gene_name": "RNF25", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZKQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKQ3" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0ZKQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKQ3" } ] } ] }, { "uniprot_ac": "A0A8V0ZL18", "gene_name": "HECTD2", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZL18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZL18" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0ZL18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZL18" } ] } ] }, { "uniprot_ac": "A0A8V0ZM17", "gene_name": "UBR1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZM17", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM17" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0ZM17", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM17" } ] } ] }, { "uniprot_ac": "A0A8V0ZS27", "gene_name": "TRIP12", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZS27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS27" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0ZS27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS27" } ] } ] }, { "uniprot_ac": "A0A8V0ZSA3", "gene_name": "HERC4", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZSA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSA3" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0ZSA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSA3" } ] } ] }, { "uniprot_ac": "A0A8V0ZSH4", "gene_name": "RNF111", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZSH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSH4" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0ZSH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSH4" } ] } ] }, { "uniprot_ac": "A0A8V0ZVX3", "gene_name": "NEDD4", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZVX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVX3" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0ZVX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVX3" } ] } ] }, { "uniprot_ac": "A0A8V0ZW26", "gene_name": "ZNRF1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZW26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZW26" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0ZW26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZW26" } ] } ] }, { "uniprot_ac": "A0A8V0ZZH3", "gene_name": "ITCH", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZZH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZH3" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0ZZH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZH3" } ] } ] }, { "uniprot_ac": "A0A8V1A052", "gene_name": "UBE2E3", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V1A052", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A052" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V1A052", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A052" } ] } ] }, { "uniprot_ac": "A0A8V1A0X2", "gene_name": "UBE3C", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1A0X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0X2" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V1A0X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0X2" } ] } ] }, { "uniprot_ac": "A0A8V1A0Z6", "gene_name": "UBE4A", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1A0Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0Z6" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1A0Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0Z6" } ] } ] }, { "uniprot_ac": "A0A8V1A1I4", "gene_name": "UBE2Z", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V1A1I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1I4" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V1A1I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1I4" } ] } ] }, { "uniprot_ac": "A0A8V1A1N8", "gene_name": "HERC1", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1A1N8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1N8" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V1A1N8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1N8" } ] } ] }, { "uniprot_ac": "A0A8V1A233", "gene_name": "RNF220", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1A233", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A233" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1A233", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A233" } ] } ] }, { "uniprot_ac": "A0A8V1A2W7", "gene_name": "RNF41", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1A2W7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2W7" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1A2W7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2W7" } ] } ] }, { "uniprot_ac": "A0A8V1A4H7", "gene_name": "UBE2L3", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V1A4H7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4H7" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V1A4H7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4H7" } ] } ] }, { "uniprot_ac": "A0A8V1A5P4", "gene_name": "UBE2G2", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V1A5P4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5P4" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V1A5P4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5P4" } ] } ] }, { "uniprot_ac": "A0A8V1A7P9", "gene_name": "DCAF1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A7P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P9" } ] } ] }, { "uniprot_ac": "A0A8V1A7T1", "gene_name": "RNF123", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1A7T1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7T1" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1A7T1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7T1" } ] } ] }, { "uniprot_ac": "A0A8V1A9M0", "gene_name": "RNF34", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1A9M0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9M0" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1A9M0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9M0" } ] } ] }, { "uniprot_ac": "A0A8V1AC19", "gene_name": "UBA7", "activity": [ { "ec_number": "6.2.1.45", "activity": "ATP + ubiquitin + [E1 ubiquitin-activating enzyme]-L-cysteine = AMP + diphosphate + S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V1AC19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC19" } ] }, { "ec_number": "6.2.1.45", "activity": "", "evidence": [ { "id": "A0A8V1AC19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC19" } ] } ] }, { "uniprot_ac": "A0A8V1AC55", "gene_name": "SMURF2", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1AC55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC55" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V1AC55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC55" } ] } ] }, { "uniprot_ac": "A0A8V1ACU3", "gene_name": "UBE2O", "activity": [ { "ec_number": "2.3.2.24", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E1 ubiquitin-activating enzyme]-L-cysteine + N(6)-monoubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1ACU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACU3" } ] }, { "ec_number": "2.3.2.24", "activity": "", "evidence": [ { "id": "A0A8V1ACU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACU3" } ] } ] }, { "uniprot_ac": "A0A8V1AKB8", "gene_name": "TRIM32", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1AKB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKB8" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1AKB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKB8" } ] } ] }, { "uniprot_ac": "A0A8V1AL09", "gene_name": "TRIM37", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1AL09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL09" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1AL09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL09" } ] } ] }, { "uniprot_ac": "A0A8V1ALH0", "gene_name": "RNF213", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1ALH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALH0" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1ALH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALH0" } ] } ] }, { "uniprot_ac": "A0A8V1AML5", "gene_name": "TRIM50", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", 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ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1BZ35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BZ35" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "E1BZ35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BZ35" } ] } ] }, { "uniprot_ac": "E1C3Q9", "gene_name": "SIAH2", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1C3Q9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C3Q9" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "E1C3Q9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C3Q9" } ] } ] }, { "uniprot_ac": "E1C656", "gene_name": "HACE1", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1C656", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C656" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "E1C656", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C656" } ] } ] }, { "uniprot_ac": "E1C982", "gene_name": "AREL1", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1C982", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C982" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "E1C982", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C982" } ] } ] }, { "uniprot_ac": "F1NC08", "gene_name": "RNF138", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1NC08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NC08" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "F1NC08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NC08" } ] } ] }, { "uniprot_ac": "F1NL19", "gene_name": "CDC34", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating 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"F1NVY8", "gene_name": "LNX1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1NVY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NVY8" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "F1NVY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NVY8" } ] } ] }, { "uniprot_ac": "F1P2G0", "gene_name": "SIAH1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1P2G0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P2G0" } ] }, { "ec_number": "2.3.2.27", "activity": "", 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ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "R4GIV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GIV8" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "R4GIV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GIV8" } ] } ] }, { "uniprot_ac": "Z4YJC3", "gene_name": "TRIM71", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "Z4YJC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Z4YJC3" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "Z4YJC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Z4YJC3" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YPW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPW4" }, { "id": "PS50127", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50127" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "UBC core", "eco_id": "ECO_0000259", "start_pos": 12, "end_pos": 162, "start_aa": "Thr", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.3.2.23", "ec_name": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "2.3.2.23", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.3.2.23" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 3, "end_pos": 5 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": 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"evidence": [ { "id": "A0A8V0YPW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPW5/entry#names_and_taxonomy" } ] }, { "name": "cytokine receptor common subunit beta isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015143698", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015143698" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015143698", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015143698" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPW5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPW5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CSF2RB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPW5", "locus": {} } ], "crossref": [ { "id": "A0A8V0YPW5", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YPW5", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00063", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00063", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": 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"https://www.reactome.org/PathwayBrowser/#R-GGA-5673001", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-912526", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-912526", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_015143698", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015143698", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YPW5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPW5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YPW5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPW5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKMKGFFIFLLNLPVVFSDQAIKESVPMKSLRCHNDYKSLMTCTWKEHSEAHALLGLTLYHTRVTENVSEEMHCEKELGEDLHEASDPYTHWICWKTVKDFQSGVDDYYSFKPQQILEAHLEVHPFQNVQPLPPQNLSVRESSGDFLLTWTAPDGSQGLGSALEYEVAYKREWESWEKAASRLLSNTTRCHLSHLIPGSRYVARVRARPEQGRGFSGHYSEWSTDVSWETPEGGIHPRNLHCLFNGAYLMCSWEVKKVIATSVIFGLFFRPTPASVEKECSPVYEKNLPHVPYVVQSCGIPVSNISSRSQYQVSVRTKTEEKWIEAYKNIKVLPPANVSVELMKSQEYELRWKKHSLRYGFIKQKYQVQFWIHNQYEKTVQTINITNDEPPFIFTDQMLSPSAKYRGRMRAMVNYQDYQGYWSEWSEEFTWETENVLSPVVLPLMLPVIIITLLVVAYCSFKYFLRQKKLWEEKIPNPSKSLLIQSYLKKVPLRNECASRQLDINKCSLAENMDQPSFLQVVDRQTKTLAEPPEAQTERMEVSSAALDPQNPYHALNVPEHAPVVCPSQIPGHSFSVSRTNGADASITSQTAITCFAFNGPYLYSPVMSSQPEMHQTLEVTSNPMGKQEKAVSLQYVSLPDKASPQAAQRQEQPGAGPLQPFLLPDQKEVMRYLNDEKEVSPLPTTCEKSTDVRTEEQKSPEAPGCPTFLQQCPLEYITTDSLLLPSTSNATHLPLVTAGGKPCDTQEP", "length": 749, "header": "tr|A0A8V0YPW5-1|A0A8V0YPW5_CHICK Isoform 1 of Colony stimulating factor 2 receptor subunit beta OS=Gallus gallus OX=9031 GN=CSF2RB PE=4 SV=1 CANONICAL=A0A8V0YPW5-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YPW5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPW5/entry#A0A8V0YPW5-1", "sequence": { "sequence": "MKMKGFFIFLLNLPVVFSDQAIKESVPMKSLRCHNDYKSLMTCTWKEHSEAHALLGLTLYHTRVTENVSEEMHCEKELGEDLHEASDPYTHWICWKTVKDFQSGVDDYYSFKPQQILEAHLEVHPFQNVQPLPPQNLSVRESSGDFLLTWTAPDGSQGLGSALEYEVAYKREWESWEKAASRLLSNTTRCHLSHLIPGSRYVARVRARPEQGRGFSGHYSEWSTDVSWETPEGGIHPRNLHCLFNGAYLMCSWEVKKVIATSVIFGLFFRPTPASVEKECSPVYEKNLPHVPYVVQSCGIPVSNISSRSQYQVSVRTKTEEKWIEAYKNIKVLPPANVSVELMKSQEYELRWKKHSLRYGFIKQKYQVQFWIHNQYEKTVQTINITNDEPPFIFTDQMLSPSAKYRGRMRAMVNYQDYQGYWSEWSEEFTWETENVLSPVVLPLMLPVIIITLLVVAYCSFKYFLRQKKLWEEKIPNPSKSLLIQSYLKKVPLRNECASRQLDINKCSLAENMDQPSFLQVVDRQTKTLAEPPEAQTERMEVSSAALDPQNPYHALNVPEHAPVVCPSQIPGHSFSVSRTNGADASITSQTAITCFAFNGPYLYSPVMSSQPEMHQTLEVTSNPMGKQEKAVSLQYVSLPDKASPQAAQRQEQPGAGPLQPFLLPDQKEVMRYLNDEKEVSPLPTTCEKSTDVRTEEQKSPEAPGCPTFLQQCPLEYITTDSLLLPSTSNATHLPLVTAGGKPCDTQEP", "length": 749, "header": "tr|A0A8V0YPW5-1|A0A8V0YPW5_CHICK Isoform 1 of Colony stimulating factor 2 receptor subunit beta OS=Gallus gallus OX=9031 GN=CSF2RB PE=4 SV=1 CANONICAL=A0A8V0YPW5-1" }, "locus": { "chromosome": "1", "start_pos": 51594851, "end_pos": 51584714, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010035683.1", "url": "https://www.ensembl.org/id/ENSGALT00010035683.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020704.1", "url": "https://www.ensembl.org/id/ENSGALP00010020704.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:101750812", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:101750812", "resource": "KEGG Pathway" }, { "id": "R-GGA-512988", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-512988", "resource": "Reactome", "description": "Interleukin-3, Interleukin-5 and GM-CSF signaling" }, { "id": "R-GGA-5673001", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5673001", "resource": "Reactome", "description": "RAF/MAP kinase cascade" }, { "id": "R-GGA-912526", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-912526", "resource": "Reactome", "description": "Interleukin receptor SHC signaling" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "interleukin-5-mediated signaling pathway", "id": "GO:0038043", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038043", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPW5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPW5" } ], "pmid": "" }, { "name": "interleukin-3-mediated signaling pathway", "id": "GO:0038156", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038156", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPW5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPW5" } ], "pmid": "" }, { "name": "immunoglobulin mediated immune response", "id": "GO:0016064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016064", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPW5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPW5" } ], "pmid": "" }, { "name": "cell surface receptor signaling pathway via JAK-STAT", "id": "GO:0007259", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007259", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPW5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPW5" } ], "pmid": "" }, { "name": "positive regulation of leukocyte proliferation", "id": "GO:0070665", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070665", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPW5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPW5" } ], "pmid": "" }, { "name": "granulocyte-macrophage colony-stimulating factor signaling pathway", "id": "GO:0038157", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038157", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPW5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPW5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "external side of plasma membrane", "id": "GO:0009897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009897", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPW5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPW5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "cytokine receptor activity", "id": "GO:0004896", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004896", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPW5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPW5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 136, "end_pos": 138, "annotation": "n_glycosylation_sequon" }, { "start_pos": 186, "end_pos": 188, "annotation": "n_glycosylation_sequon" }, { "start_pos": 304, "end_pos": 306, "annotation": "n_glycosylation_sequon" }, { "start_pos": 337, "end_pos": 339, "annotation": "n_glycosylation_sequon" }, { "start_pos": 384, "end_pos": 386, "annotation": "n_glycosylation_sequon" }, { "start_pos": 67, "end_pos": 69, "annotation": "n_glycosylation_sequon" }, { "start_pos": 730, "end_pos": 732, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YPW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPW5" }, { "id": "PS50853", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50853" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Fibronectin type-III", "eco_id": "ECO_0000259", "start_pos": 133, "end_pos": 233, "start_aa": "Pro", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 136, "end_pos": 138 }, { "start_pos": 186, "end_pos": 188 }, { "start_pos": 304, "end_pos": 306 }, { "start_pos": 337, "end_pos": 339 }, { "start_pos": 384, "end_pos": 386 }, { "start_pos": 67, "end_pos": 69 }, { "start_pos": 730, "end_pos": 732 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YPW6-1", "uniprot_ac": "A0A8V0YPW6", "uniprot_id": "A0A8V0YPW6_CHICK", "mass": { "chemical_mass": 257932.0, "monoisotopic_mass": 257932.0 }, "refseq": {}, "gene_names": [ { "name": "DOP1B", "type": "recommended", "evidence": [ { "id": "A0A8V0YPW6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPW6" } ] } ], "protein_names": [ { "name": "DOP1 leucine zipper like protein B", "type": "synonym", "evidence": [ { "id": "A0A8V0YPW6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPW6/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPW6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPW6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "DOP1B", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPW6", "locus": { "chromosome": "1", "start_pos": 106723182, "end_pos": 106674920, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012993", "url": "https://www.ensembl.org/id/ENSGALG00010012993" } ] } } ], "crossref": [ { "id": "IPR007249", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007249", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040314", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040314", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056457", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056457", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056458", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056458", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056459", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056459", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YPW6", "url": "https://www.orthodb.org/?gene=A0A8V0YPW6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14042", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14042", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14042:SF23", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14042:SF23", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04118", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04118", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24597", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24597", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24598", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24598", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24601", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24601", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF26706", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF26706", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YPW6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPW6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YPW6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPW6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": 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"length": 2283, "header": "tr|A0A8V0YPW6-1|A0A8V0YPW6_CHICK Isoform 1 of DOP1 leucine zipper like protein B OS=Gallus gallus OX=9031 GN=DOP1B PE=1 SV=1 CANONICAL=A0A8V0YPW6-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YPW6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPW6/entry#A0A8V0YPW6-1", "sequence": { "sequence": "MDPEEQELLGDYRYRNYSSAIEKALRNFESSSEWADLISSLGKLNKALQSNLKYSLLPRRLIISKRLSQCLHPALPSGVHLKALETYEIIFKIIGTKWLAKDLFLYSSGLFPLLANAAMSVRPVLLGLYEKYFLPLQKSLLPGLQAFVIGLLPGLEEGSEIYDRTDALLVKLSLLMGKEVFYGALWGSVLVSPSIRLPASLFVVSHINRELSGKQQKYMLGTDYKLTIKSLCVSVLDSNVLVQRNTLEVILFFFPFDTALDYNENAILLRRTDLVHVLSAATQTLLRRDMSLNRRLYAWLLGSDIKGGTFAPESTTSEDHAIYFFGKYSRDLLVESLAEILHQKFSESDTEEQHQAYLKPFRILISLLDKPEIGPQVVGDLFLEVIRAFYSYCKDALGSDLKLSYNQSGNVLASAIKENKNASEIVKTVNVLITSLSTDFLWDYMTKCFEDCFRKKSTQTRDPPENVSMPPTISELCTLLVFLLDVIPLELYSEVQTQYLPQMLSYMVQSLLENVEILSLPELTHALKTCFKVLSKVQMPPSYLDIETGSRNGSPVKKENGDVTLETKSVLQEEDETPFPPLKSEDSGIGLSASSPELSQHLGVPTVTLERDDVWKKGGSIQKTLHCIQELVAKFSSKYIFGVQFQEANNESISAINLSGKEKKENGYRLSESASKKKIAKQITVPQFKQMLSELFSVRGSPFKNKSSNLSSDCNSDNKKEKEEDWDLEQVMFVLGPLRADCKEAFAAACHLLLDCTTFPVYLSEEEMEQLYISLFQFPGGCDASFPLWLKSLMTICCCVNDCYVQNVSIFTLLEVINHSQSLALVIEDRMKRYKVSGHNPFLGKLQMVTLPPIAPGVLKIISEKTDFYQRVACALWNQLNKETREHHIACVELFYRLHCLAPSANICEDIICHALLDHDKGTRLEALFRFSVMWHLTREIQGSRVSSHNRSFDRSLFVVLDSLNCSDGAIGAAAQGWLIRALSLNDVARILEPVLLLLLHPKTQRTSIHYIKQKNLTEDIHDWLCKKKVSWKESGVSESNSEENLPLSQFTAVDREAIWAEVEKDPEKLELKTEQSENDASCNPVALHEADGDQDNSEHTESADTSTGRDSENTSSFSPSLELQEMSNEDNDSAAADGKENTNQTFLPESSKSSVALNLVRADSERTQASESLSSDEEVDLELQEITNSRLLKQQKEKQEMAEALFKHMLLYLQPYDSKRVLYAFSILEAVLKTNPKEFVEAVASTSMDTSSTAHLNLIYNLLARHQEALVGQSFYGKLQTQSPTMCPHSLLIELLTYLCLSFLRSYYPCYLKVTHRDVLGNRDVQVKSVEVLIRMMTQLATMAKAAENKNVEFIRNLLGRCKIQEFVLLSLSASMYTSQKRYELLMVGGVNHIPAEDLFEESLINFGHDQIWSEHPLQIELLKLLQVLIVLEHHLGQTPEEQENQPDLSREWQQALNFQQAIGAMQYVYPHPITSQGLFVSAVVRGLQPEYGYGMHPTWVSLVTCSLPYFGKSLGWTVAPFVVQICKNLDELVKQYENEAVKISMKTSASLTSKRENVTPDYPLTLLEGLTTIGHFCLLDHPNQTKKSSCLAEPANLRNARNAILEELPRIINTMSLLWNVIKREDSQKRPTDFFGTTKGSSSVYFKATKTLRTKILDFLNPLTAQLGIQLMTAVAAVWNSKKPHRNQSKIKILPVASASQLILVDLICALNTLKTDTILHLVKEVVKKPSQIKGEEKSSLVDIPMLQFGYAFIQRLPVTALQENFQSLLGLLKESVQLNLAPPGHFLLLSTLNDFVTRTPTLENKKDQKDLQEVTQKILEAVGNVAGSSLEQTSWLSRNLEVKAQPQILPDEFNTEDVNDTSVAPSSMVSASAPSIYSVQALSLLAEVLASLLDMVYRSDEKEKAVPLISRLLYYVFPYLRNHSTYNIPSFRAGSQLLSSLSGYAYTKRAWKKEVLELYMDPAFFQMDTSCTHWRSIIDHLLTHEKTMFKDLMNMQSSALKLYPSFEQKAMLLKRQAFAVFSGEIDQYHLYLPLIQERLTENLRVGQTSLVAAQMFLLFRVLLLRISPQHLTSLWPIMVTELIQTFLQLEEELTEEDEPSKSNSKLSKQKVSGDGSGSDIQQNELSLYLSACKFLDTALSFPPDRMQLFQMYKWAFVPEVDTESSTVTSHLVENHQECRPHIIRIMDLLKMKYGERNNTDEGISKRHKFPLLNFRTISSITQLMPFFKTLCCAFTTKRSEAQNSHTSASLPVDYVGGNSMKILQQLEESVECDFLENMES", "length": 2283, "header": "tr|A0A8V0YPW6-1|A0A8V0YPW6_CHICK Isoform 1 of DOP1 leucine zipper like protein B OS=Gallus gallus OX=9031 GN=DOP1B PE=1 SV=1 CANONICAL=A0A8V0YPW6-1" }, "locus": { "chromosome": "1", "start_pos": 106720195, "end_pos": 106677377, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031218.1", "url": "https://www.ensembl.org/id/ENSGALT00010031218.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018190.1", "url": "https://www.ensembl.org/id/ENSGALP00010018190.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPW6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPW6" } ], "pmid": "" }, { "name": "endosome", "id": "GO:0005768", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005768", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPW6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPW6" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPW6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPW6" } ], "pmid": "" }, { "name": "early endosome membrane", "id": "GO:0031901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031901", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPW6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPW6" } ], "pmid": "" }, { "name": "trans-Golgi network", "id": "GO:0005802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005802", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPW6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPW6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPW6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPW6" } ], "pmid": "" }, { "name": "cognition", "id": "GO:0050890", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050890", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPW6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPW6" } ], "pmid": "" }, { "name": "Golgi to endosome transport", "id": "GO:0006895", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006895", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPW6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPW6" } ], "pmid": "" }, { "name": "embryonic pattern specification", "id": "GO:0009880", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009880", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPW6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPW6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1016, "end_pos": 1018, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1114, "end_pos": 1116, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1132, "end_pos": 1134, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1144, "end_pos": 1146, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1559, "end_pos": 1561, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1585, "end_pos": 1587, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1689, "end_pos": 1691, "annotation": "n_glycosylation_sequon" }, { "start_pos": 16, "end_pos": 18, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1862, "end_pos": 1864, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1925, "end_pos": 1927, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2200, "end_pos": 2202, "annotation": "n_glycosylation_sequon" }, { "start_pos": 406, "end_pos": 408, "annotation": "n_glycosylation_sequon" }, { "start_pos": 421, "end_pos": 423, "annotation": "n_glycosylation_sequon" }, { "start_pos": 466, "end_pos": 468, "annotation": "n_glycosylation_sequon" }, { "start_pos": 552, "end_pos": 554, "annotation": "n_glycosylation_sequon" }, { "start_pos": 650, "end_pos": 652, "annotation": "n_glycosylation_sequon" }, { "start_pos": 657, "end_pos": 659, "annotation": "n_glycosylation_sequon" }, { "start_pos": 705, "end_pos": 707, "annotation": "n_glycosylation_sequon" }, { "start_pos": 709, "end_pos": 711, "annotation": "n_glycosylation_sequon" }, { "start_pos": 807, "end_pos": 809, "annotation": "n_glycosylation_sequon" }, { "start_pos": 818, "end_pos": 820, "annotation": "n_glycosylation_sequon" }, { "start_pos": 950, "end_pos": 952, "annotation": "n_glycosylation_sequon" }, { "start_pos": 965, "end_pos": 967, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YPW6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPW6" }, { "id": "PF04118", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04118" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "DOP1 N-terminal", "eco_id": "ECO_0000259", "start_pos": 12, "end_pos": 304, "start_aa": "Tyr", "end_aa": "Asp", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0YPW6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPW6" }, { "id": "PF24598", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24598" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "DOP1-like C-terminal", "eco_id": "ECO_0000259", "start_pos": 1754, "end_pos": 2235, "start_aa": "Ala", "end_aa": "Cys", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0YPW6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPW6" }, { "id": "PF24601", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24601" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "DOP1-like TPR", "eco_id": "ECO_0000259", "start_pos": 1205, "end_pos": 1582, "start_aa": "Ala", "end_aa": "Asp", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0YPW6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPW6" }, { "id": "PF24597", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24597" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "DOP1-like middle TPR", "eco_id": "ECO_0000259", "start_pos": 324, "end_pos": 512, "start_aa": "Phe", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1016, "end_pos": 1018 }, { "start_pos": 1114, "end_pos": 1116 }, { "start_pos": 1132, "end_pos": 1134 }, { "start_pos": 1144, "end_pos": 1146 }, { "start_pos": 1559, "end_pos": 1561 }, { "start_pos": 1585, "end_pos": 1587 }, { "start_pos": 1689, "end_pos": 1691 }, { "start_pos": 16, "end_pos": 18 }, { "start_pos": 1862, "end_pos": 1864 }, { "start_pos": 1925, "end_pos": 1927 }, { "start_pos": 2200, "end_pos": 2202 }, { "start_pos": 406, "end_pos": 408 }, { "start_pos": 421, "end_pos": 423 }, { "start_pos": 466, "end_pos": 468 }, { "start_pos": 552, "end_pos": 554 }, { "start_pos": 650, "end_pos": 652 }, { "start_pos": 657, "end_pos": 659 }, { "start_pos": 705, "end_pos": 707 }, { "start_pos": 709, "end_pos": 711 }, { "start_pos": 807, "end_pos": 809 }, { "start_pos": 818, "end_pos": 820 }, { "start_pos": 950, "end_pos": 952 }, { "start_pos": 965, "end_pos": 967 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YPX4-1", "uniprot_ac": "A0A8V0YPX4", "uniprot_id": "A0A8V0YPX4_CHICK", "mass": { "chemical_mass": 36665.0, "monoisotopic_mass": 36665.0 }, "refseq": { "ac": "XP_015152662", "name": "filamin-binding LIM protein 1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015152662" }, "gene_names": [ { "name": "FBLIM1", "type": "recommended", "evidence": [ { "id": "A0A8V0YPX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPX4" } ] }, { "name": "FBLIM1", "type": "synonym", "evidence": [ { "id": "XP_015152662", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015152662" } ] } ], "protein_names": [ { "name": "Filamin binding LIM protein 1", "type": "synonym", "evidence": [ { "id": "A0A8V0YPX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPX4/entry#names_and_taxonomy" } ] }, { "name": "filamin-binding LIM protein 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015152662", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015152662" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052552.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015152662.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015152662", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015152662" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPX4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPX4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "FBLIM1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPX4", "locus": { "chromosome": "21", "start_pos": 4228297, "end_pos": 4224383, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010016550", "url": "https://www.ensembl.org/id/ENSGALG00010016550" } ] } } ], "crossref": [ { "id": "A0A8V0YPX4", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YPX4", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd09372", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09372", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "419458", "url": "https://www.ncbi.nlm.nih.gov/gene/419458", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001781", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001781", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:419458", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419458", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CEVCVIQ", "url": "https://omabrowser.org/oma/group/CEVCVIQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YPX4", "url": "https://www.orthodb.org/?gene=A0A8V0YPX4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YWR0", "url": "https://www.orthodb.org/?gene=A0A8V0YWR0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24207", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24207", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24207:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24207:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00412", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00412", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-446353", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-446353", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_015152662", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015152662", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YPX4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPX4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YPX4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPX4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YWR0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YWR0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YWR0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YWR0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSSPSAVSAMLPRKAEKRMASSVFITLASPRRETAPREQPQAGVSLAVPEGTPRPPVTPALPNGESSPRSPAVPSSPPALILSEAPQPPSVEALAPALQQLDLAAPAMLQAPFAFPAELRPPQVCQGQADKPQWQDANGHIERDSSQDICAFCHKAVGPREPTVEAMRKQYHADCFTCRTCQRRLAGQRYYQRDGRPTCDACYQATLEKCAKCQGLITERIVRALGKGFHPGCFACAACGRAIGAESFAVDEQGKVYCVADFYRKFAPVCGACKHPIIPDEDTYKIECLGRSFHESCYRCESCGTLLSPEPTEDGCYPLGHHLLCKACHICRQNESSC", "length": 338, "header": "tr|A0A8V0YPX4-1|A0A8V0YPX4_CHICK Isoform 1 of Filamin binding LIM protein 1 OS=Gallus gallus OX=9031 GN=FBLIM1 PE=4 SV=1 CANONICAL=A0A8V0YPX4-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YPX4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPX4/entry#A0A8V0YPX4-1", "sequence": { "sequence": "MSSPSAVSAMLPRKAEKRMASSVFITLASPRRETAPREQPQAGVSLAVPEGTPRPPVTPALPNGESSPRSPAVPSSPPALILSEAPQPPSVEALAPALQQLDLAAPAMLQAPFAFPAELRPPQVCQGQADKPQWQDANGHIERDSSQDICAFCHKAVGPREPTVEAMRKQYHADCFTCRTCQRRLAGQRYYQRDGRPTCDACYQATLEKCAKCQGLITERIVRALGKGFHPGCFACAACGRAIGAESFAVDEQGKVYCVADFYRKFAPVCGACKHPIIPDEDTYKIECLGRSFHESCYRCESCGTLLSPEPTEDGCYPLGHHLLCKACHICRQNESSC", "length": 338, "header": "tr|A0A8V0YPX4-1|A0A8V0YPX4_CHICK Isoform 1 of Filamin binding LIM protein 1 OS=Gallus gallus OX=9031 GN=FBLIM1 PE=4 SV=1 CANONICAL=A0A8V0YPX4-1" }, "locus": { "chromosome": "21", "start_pos": 4227955, "end_pos": 4226100, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010039853.1", "url": "https://www.ensembl.org/id/ENSGALT00010039853.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023064.1", "url": "https://www.ensembl.org/id/ENSGALP00010023064.1" } ] } }, { "isoform_ac": "A0A8V0YWR0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPX4/entry#A0A8V0YWR0-1", "sequence": { "sequence": "MSSPSAVSAMLPRKAEKRMASSVFITLASPRRETAPREQPQAGVSLAVPEGTPRPPVTPALPNGVPSSPPALILSEAPQPPSVEALAPALQQLDLAAPAMLQAPFAFPAELRPPQVCQGQADKPQWQDANGHIERDSSQDICAFCHKAVGPREPTVEAMRKQYHADCFTCRTCQRRLAGQRYYQRDGRPTCDACYQATLEKCAKCQGLITERIVRALGKGFHPGCFACAACGRAIGAESFAVDEQGKVYCVADFYRKFAPVCGACKHPIIPDEDTYKIECLGRSFHESCYRCESCGTLLSPEPTEDGCYPLGHHLLCKACHICRQNESSC", "length": 330, "header": "tr|A0A8V0YWR0-1|A0A8V0YWR0_CHICK Computationally mapped isoform of Filamin binding LIM protein 1 OS=Gallus gallus OX=9031 GN=FBLIM1 PE=4 SV=1 CANONICAL=A0A8V0YPX4-1" }, "locus": { "chromosome": "21", "start_pos": 4227955, "end_pos": 4226100, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010039859.1", "url": "https://www.ensembl.org/id/ENSGALT00010039859.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023068.1", "url": "https://www.ensembl.org/id/ENSGALP00010023068.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 58, "start_aa": "Thr", "end_pos": 58, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr58", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:419458", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419458", "resource": "KEGG Pathway" }, { "id": "R-GGA-446353", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-446353", "resource": "Reactome", "description": "Cell-extracellular matrix interactions" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287BKY8-1", "protein_name": "Filamin-binding LIM protein 1", "gene_name": "FBLIM1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTFGAPSVAGWVAAPPHPEPCPRLSPTLSPAPPGAKAMASKPEKRVASSVFITLAPPRRDEAVVEEVKRAACEARPGCPRESPVPVKAPGAGSAGRLRSWAPPGRASAPVPAVPPQLSNGGCSLPPPPLDGEDSLPDLDLLPPPPPPPPPMYLPPPDQEPPASVGALVSDLEQLHLPPPPPPPQALVEGPPLQPQPSPLRPMEELPPPPEEPVSLPEREASTDICAFCHKTVSPRELAVEAMKRQYHAQCFTCRVCRRQLAGQSFYQKDGRPLCEPCYQDTLEKCGKCGEGVREHIIRALGQAFHPTCFTCVTCARCIGDESFALDSQNEVYCLDDFYRKFAPVCSICENPIIPRDGKDAFKIECMGRNFHENCYRCEDCRILLSVEPTDQGCYPLNNRLFCKPCHVKRSAASCC", "length": 415 }, "evidence": [ { "id": "A0A8V0YPX4", "url": "https://omabrowser.org/oma/group/A0A8V0YPX4/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0ABK0LP70-1", "protein_name": "Filamin-binding LIM protein 1", "gene_name": "Fblim1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRPDKALKIPSAAPSPRSSPLPDDVKGEHGCPAANIWPPRWMFPRKQAEWNGGQSRGRGGGGGFLKSHSLSQRTRLECVDRKKLVWIGLFGGRGGAWSGGGGLYGPGKKKSKDAPRTPRLLDSLKGFQACWRAKETYFELLLGPRDRGSLQLSGAGLNFGPCLPVGISISAPQELIMASKQEKRVASSVFITLAPPRRDVAVTEEVTQAVCEARRARPWETLPTKTPGAAVGRSPKTWTPSGRTTASLPEVPPQLSNGGCSLPPPPLNEEDLDLLPPPPPPPSAYLPLPEEEPPVVPGSSLISDLEQLHLPPPPPPPLLQAPSKGSSVQPQPVQVRPSEEELPPPPEEPVTLPEREASTDVCGFCHKPVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQRFYQKDGRPLCEPCYQDTLEKCGKCGEVVQEHVIRALGKAFHPPCFTCVTCARCISDESFALDNQNQVYCVTDFYRKFAPVCSICENPIIPRDGKDAFKIECMGRNFHENCYRCEDCSVLLSVEPTDQGCYPLNDHLFCKPCHMKRSAAGCC", "length": 552 }, "evidence": [ { "id": "A0A8V0YPX4", "url": "https://omabrowser.org/oma/group/A0A8V0YPX4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q1JQB5-1", "protein_name": "Filamin-binding LIM protein 1", "gene_name": "FBLIM1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MASKPEKRVASSVFITLVPPRRDEAVVEEVRRAACEAWPGRPWESAPTKAPGAGSVGKLRSWMPPGRAAAPGPAVPPQLSNGGCSLPPPPLDVDDALPDLDLLPPPPPPPAADLPPPDEEPHSAMGASLISDLEQLHLPPPPPPPQALVEGPPLQPRPSHLKPAEEELPPPPEEPVSFPEREASTDICAFCHKTVSPRELAVEAMKRQYHAQCFTCRVCRRQLAGQSFYQKDGRPLCEPCYQDTLEKCGKCGEVVREHIIRALGQAFHPSCFTCVTCARRIGDESFALDSQNEVYCLDDFYRKFAPVCSICENPIIPRDGKDAFKIECMGRNFHENCYRCEDCRVLLSVEPTDQGCYPLNNRLFCKPCHVKRSAAGCC", "length": 378 }, "evidence": [ { "id": "A0A8V0YPX4", "url": "https://omabrowser.org/oma/group/A0A8V0YPX4/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q71FD7-1", "protein_name": "Filamin-binding LIM protein 1", "gene_name": "Fblim1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASKPEKRVASSVFITLAPPRRDVAVSEEVGQAACEARRARPWEMLPTKTPGAAVGRSPKTWTPSGKTNASLSGVTPQLSNGGCSLPPPSLNEEDLDLPPPPPPPSAYLPLPEEEPPVLPGKSLISDLEQLHLPPPPPPPPPQAPSKGSSVHPPPGHAIPSEEELPPPPEEPVTLPEREVSTDVCGFCHKPVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQRFYQKDGRPLCEPCYQDTLEKCGKCGEVVQEHVIRALGKAFHPPCFTCVTCARCISDESFALDSQNQVYCVADFYRKFAPVCSICENPIIPRDGKDAFKIECMGRNFHENCYRCEDCSVLLSVEPTDQGCYPLNDHLFCKPCHLKRSAAGCC", "length": 375 }, "evidence": [ { "id": "A0A8V0YPX4", "url": "https://omabrowser.org/oma/group/A0A8V0YPX4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8WUP2-1", "protein_name": "Filamin-binding LIM protein 1", "gene_name": "FBLIM1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MASKPEKRVASSVFITLAPPRRDVAVAEEVRQAVCEARRGRPWEAPAPMKTPEAGLAGRPSPWTTPGRAAATVPAAPMQLFNGGCPPPPPVLDGEDVLPDLDLLPPPPPPPPVLLPSEEEAPAPMGASLIADLEQLHLSPPPPPPQAPAEGPSVQPGPLRPMEEELPPPPAEPVEKGASTDICAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPCYQDTLERCGKCGEVVRDHIIRALGQAFHPSCFTCVTCARCIGDESFALGSQNEVYCLDDFYRKFAPVCSICENPIIPRDGKDAFKIECMGRNFHENCYRCEDCRILLSVEPTDQGCYPLNNHLFCKPCHVKRSAAGCC", "length": 373 }, "evidence": [ { "id": "A0A8V0YPX4", "url": "https://omabrowser.org/oma/group/A0A8V0YPX4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "regulation of integrin activation", "id": "GO:0033623", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033623", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPX4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPX4" } ], "pmid": "" }, { "name": "cell-cell adhesion", "id": "GO:0098609", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098609", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPX4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPX4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPX4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPX4" } ], "pmid": "" }, { "name": "focal adhesion", "id": "GO:0005925", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005925", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPX4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPX4" } ], "pmid": "" }, { "name": "stress fiber", "id": "GO:0001725", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001725", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPX4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPX4" } ], "pmid": "" }, { "name": "cell periphery", "id": "GO:0071944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071944", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPX4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPX4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPX4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPX4" } ], "pmid": "" }, { "name": "filamin binding", "id": "GO:0031005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031005", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YPX4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPX4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 334, "end_pos": 336, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YPX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPX4" }, { "id": "PS50023", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50023" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "LIM zinc-binding", "eco_id": "ECO_0000259", "start_pos": 148, "end_pos": 209, "start_aa": "Asp", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 58 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 334, "end_pos": 336 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": 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"field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YQ08-1", "uniprot_ac": "A0A8V0YQ08", "uniprot_id": "A0A8V0YQ08_CHICK", "mass": { "chemical_mass": 70187.0, "monoisotopic_mass": 70187.0 }, "refseq": {}, "gene_names": [ { "name": "NOS1AP", "type": "recommended", "evidence": [ { "id": "A0A8V0YQ08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ08" } ] } ], "protein_names": [ { "name": "Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein", "type": "recommended", "evidence": [ { "id": "A0A8V0YQ08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ08/entry#names_and_taxonomy" } ] }, { "name": "C-terminal PDZ ligand of neuronal nitric oxide synthase protein", "type": "synonym", "evidence": [ { "id": "A0A8V0YQ08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ08/entry#names_and_taxonomy" } ] }, { "name": "Nitric oxide synthase 1 adaptor protein", "type": "synonym", "evidence": [ { "id": "A0A8V0YQ08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ08/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Adapter protein involved in neuronal nitric-oxide (NO) synthesis regulation via its association with nNOS/NOS1. The complex formed with NOS1 and synapsins is necessary for specific NO and synapsin functions at a presynaptic level. Mediates an indirect interaction between NOS1 and RASD1 leading to enhance the ability of NOS1 to activate RASD1. Competes with DLG4 for interaction with NOS1, possibly affecting NOS1 activity by regulating the interaction between NOS1 and DLG4. In kidney podocytes, plays a role in podosomes and filopodia formation through CDC42 activation.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQ08", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ08#function" }, { "database": "UniProtKB", "id": "ARBA00054402", "url": "https://www.uniprot.org/uniprotkb/ARBA00054402#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQ08", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ08" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "NOS1AP", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ08", "locus": {} } ], "crossref": [ { "id": "A0A8V0YQ08", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YQ08", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd01270", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01270", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR006020", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006020", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027851", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027851", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051133", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051133", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YQ08", "url": "https://www.orthodb.org/?gene=A0A8V0YQ08", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11232", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11232", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11232:SF76", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11232:SF76", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00640", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00640", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF15429", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15429", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YQ08", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ08", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQ08-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ08-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPAKSKYNLVDDRHDLRIPLHNEDAFQHGICFEAKYIGSLDVPRPNSRVEIVTAMRRIRYEFKAKNIKKKKVNLIVSVDGVKVILKKKKKLFPLQKKEWAWDENKMLVMHDPIYRIFYVSHDSQDLKIFSYIARDGSSNVFRCNVFKSKKKSQAMRIVRTVGQAFEVCHKLSLQHTQQNADGQEDGDSERNGDDLDVPACRLTAAERAATSAEETDIDAVELPLPGADILDFSRGVTDLDAVGKEASGDAKGCLHPEDILTASPKMLLPSSAPLPDLGTPLSAHHQMQLLQQLLQQQQQQTQVAVAQVHLLKDQLAAEAAARLEAQARVHQLLLQNKDLLQHISLLVKQVQELELKLAGNNTTGSQDSLLEITFRSSVLPVLCDPTTPQPEDTHLPQLGPGSGFPGALGSPIVDQSMFENTGAATVPTPRSQHVPAGATPQPSRPAGSQHLRNLGKAVGAKMNDLLRRKEPAGPPDVGVMEVNTSAGAALGVGQPAREDGSTGPDAFPRLDPPPPTTKKRAPRALKTPQDMLIAPQPEGGGTEEPHEPPAAHGDRAEERPGTRDLSPAERPGVLSTTGIPGPSGEQPTAALPVPDLIHKGGLETPPRTEKPLREAGLEHELPGSAGRAEPCAPSREAEGPHPDLLSFE", "length": 648, "header": "tr|A0A8V0YQ08-1|A0A8V0YQ08_CHICK Isoform 1 of Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein OS=Gallus gallus OX=9031 GN=NOS1AP PE=1 SV=1 CANONICAL=A0A8V0YQ08-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YQ08-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ08/entry#A0A8V0YQ08-1", "sequence": { "sequence": "MPAKSKYNLVDDRHDLRIPLHNEDAFQHGICFEAKYIGSLDVPRPNSRVEIVTAMRRIRYEFKAKNIKKKKVNLIVSVDGVKVILKKKKKLFPLQKKEWAWDENKMLVMHDPIYRIFYVSHDSQDLKIFSYIARDGSSNVFRCNVFKSKKKSQAMRIVRTVGQAFEVCHKLSLQHTQQNADGQEDGDSERNGDDLDVPACRLTAAERAATSAEETDIDAVELPLPGADILDFSRGVTDLDAVGKEASGDAKGCLHPEDILTASPKMLLPSSAPLPDLGTPLSAHHQMQLLQQLLQQQQQQTQVAVAQVHLLKDQLAAEAAARLEAQARVHQLLLQNKDLLQHISLLVKQVQELELKLAGNNTTGSQDSLLEITFRSSVLPVLCDPTTPQPEDTHLPQLGPGSGFPGALGSPIVDQSMFENTGAATVPTPRSQHVPAGATPQPSRPAGSQHLRNLGKAVGAKMNDLLRRKEPAGPPDVGVMEVNTSAGAALGVGQPAREDGSTGPDAFPRLDPPPPTTKKRAPRALKTPQDMLIAPQPEGGGTEEPHEPPAAHGDRAEERPGTRDLSPAERPGVLSTTGIPGPSGEQPTAALPVPDLIHKGGLETPPRTEKPLREAGLEHELPGSAGRAEPCAPSREAEGPHPDLLSFE", "length": 648, "header": "tr|A0A8V0YQ08-1|A0A8V0YQ08_CHICK Isoform 1 of Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein OS=Gallus gallus OX=9031 GN=NOS1AP PE=1 SV=1 CANONICAL=A0A8V0YQ08-1" }, "locus": { "chromosome": "8", "start_pos": 3871431, "end_pos": 3841572, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031274.1", "url": "https://www.ensembl.org/id/ENSGALT00010031274.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018225.1", "url": "https://www.ensembl.org/id/ENSGALP00010018225.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQ08", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ08" } ], "pmid": "" }, { "name": "caveola", "id": "GO:0005901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005901", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQ08", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ08" } ], "pmid": "" }, { "name": "Z disc", "id": "GO:0030018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030018", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQ08", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ08" } ], "pmid": "" }, { "name": "T-tubule", "id": "GO:0030315", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030315", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQ08", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ08" } ], "pmid": "" }, { "name": "sarcoplasmic reticulum membrane", "id": "GO:0033017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033017", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQ08", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ08" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "nitric-oxide synthase binding", "id": "GO:0050998", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050998", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQ08", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ08" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 360, "end_pos": 362, "annotation": "n_glycosylation_sequon" }, { "start_pos": 361, "end_pos": 363, "annotation": "n_glycosylation_sequon" }, { "start_pos": 483, "end_pos": 485, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YQ08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ08" }, { "id": "PS01179", "database": "PROSITE", "url": "https://prosite.expasy.org/PS01179" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PID", "eco_id": "ECO_0000259", "start_pos": 29, "end_pos": 170, "start_aa": "Gly", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 360, "end_pos": 362 }, { "start_pos": 361, "end_pos": 363 }, { "start_pos": 483, "end_pos": 485 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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"field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YQ34-1", "uniprot_ac": "A0A8V0YQ34", "uniprot_id": "A0A8V0YQ34_CHICK", "mass": { "chemical_mass": 78387.0, "monoisotopic_mass": 78387.0 }, "refseq": { "ac": "XP_420716", "name": "PGAP2-interacting protein isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_420716" }, "gene_names": [ { "name": "CWH43", "type": "recommended", "evidence": [ { "id": "A0A8V0YQ34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ34" } ] }, { "name": "CWH43", "type": "synonym", "evidence": [ { "id": "XP_420716", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_420716" } ] } ], "protein_names": [ { "name": "PGAP2-interacting protein", "type": "recommended", "evidence": [ { "id": "A0A8V0YQ34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ34/entry#names_and_taxonomy" } ] }, { "name": "Cell wall biogenesis protein 43 C-terminal homolog", "type": "synonym", "evidence": [ { "id": "A0A8V0YQ34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ34/entry#names_and_taxonomy" } ] }, { "name": "PGAP2-interacting protein isoform X1", "type": "synonym", "evidence": [ { "id": "XP_420716", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_420716" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052535.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_420716.3. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_420716", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_420716" } ] }, { "annotation": "Involved in lipid remodeling during GPI-anchor maturation.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQ34", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ34#function" }, { "database": "UniProtKB", "id": "ARBA00058459", "url": "https://www.uniprot.org/uniprotkb/ARBA00058459#function" }, { "database": "UniProtKB", "id": "A0A8V0YWX0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YWX0#function" }, { "database": "UniProtKB", "id": "A0A8V0YYF9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYF9#function" }, { "database": "UniProtKB", "id": "A0A8V0YWG9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YWG9#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQ34", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ34" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CWH43", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ34", "locus": { "chromosome": "4", "start_pos": 65743667, "end_pos": 65768164, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010016575", "url": "https://www.ensembl.org/id/ENSGALG00010016575" } ] } } ], "crossref": [ { "id": "A0A8V0YQ34", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YQ34", "database": "AlphaFoldDB", "categories": [] }, { "id": "422763", "url": "https://www.ncbi.nlm.nih.gov/gene/422763", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR036691", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036691", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051916", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051916", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR053911", "url": "https://www.ebi.ac.uk/interpro/entry/IPR053911", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR053912", "url": "https://www.ebi.ac.uk/interpro/entry/IPR053912", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057315", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057315", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:422763", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422763", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CVWYFPL", "url": "https://omabrowser.org/oma/group/CVWYFPL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YQ34", "url": "https://www.orthodb.org/?gene=A0A8V0YQ34", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YWG9", "url": "https://www.orthodb.org/?gene=A0A8V0YWG9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YWX0", "url": "https://www.orthodb.org/?gene=A0A8V0YWX0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YYF9", "url": "https://www.orthodb.org/?gene=A0A8V0YYF9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14859", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14859", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14859:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14859:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF23021", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23021", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23022", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23022", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23226", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23226", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_420716", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_420716", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YQ34", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ34", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQ34-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ34-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YWG9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YWG9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YWG9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YWG9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YWX0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YWX0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YWX0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YWX0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YYF9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYF9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YYF9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYF9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDPLWRAVLSESLLGYISWSLYHALPPMIYYFPLQTLALTGLEVFAVAFLSPVFLIVAPCWRLANNKYILALLRLTVVGSLASYQAPNASIRLFILAAGVSSSLLVQTVTLWSGNSLQRFIRIWGFILGKMMLLVLRIWYTSLNPVWSSQAANTVVLIIGLVAAAERIYSVEDERKQGANATGNTVRKAVSQPNWLLSGMAFGSLMFLTVWIFGEVSLISRWAVSGHPHTGPDPNPYGGTVLLGLAHGLMLSFWSWSSVASFAWFLIGIASSAGLLYLHTWSAAVAGNILAVFTMCVWPQLAGRFVGCLHPGKAMSTAMFTYVLELFFCVWCTAYKFVPGGVYARESSHLLLGFIMLCIGLGFLTGSKKDLNSIFEVKSDQKPFFKKSTEYIKLLLWLFVGVGLLGLGLRYRTYEKKLGRGVPKRDFSAMIWPFRFAYDNEGWSNLEGSATLLNQTGADFITVLESDASKPFIGNNDPTMWLGERLGFYTDFGPSTRDHTWGIMALSRYPIVKSTHHLLPSPEGEIAPAISMTVNFTGRLIDFVVAHFGNEEEDLDRKLQAIAVSKLLKTSSKQVVFLGYVTSAPGSRDYTELIENGNVQDIDSTDRDRWCSYIMYRGVIRLGYARISHAGLSDSEVQMAKFRIPDDLDNYVDNDRIVTDPSQVPEDVHFNPRFGSYKDGHNYDESIHHFHMSTPKYFKQTN", "length": 702, "header": "tr|A0A8V0YQ34-1|A0A8V0YQ34_CHICK Isoform 1 of PGAP2-interacting protein OS=Gallus gallus OX=9031 GN=CWH43 PE=3 SV=1 CANONICAL=A0A8V0YQ34-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YQ34-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ34/entry#A0A8V0YQ34-1", "sequence": { "sequence": "MDPLWRAVLSESLLGYISWSLYHALPPMIYYFPLQTLALTGLEVFAVAFLSPVFLIVAPCWRLANNKYILALLRLTVVGSLASYQAPNASIRLFILAAGVSSSLLVQTVTLWSGNSLQRFIRIWGFILGKMMLLVLRIWYTSLNPVWSSQAANTVVLIIGLVAAAERIYSVEDERKQGANATGNTVRKAVSQPNWLLSGMAFGSLMFLTVWIFGEVSLISRWAVSGHPHTGPDPNPYGGTVLLGLAHGLMLSFWSWSSVASFAWFLIGIASSAGLLYLHTWSAAVAGNILAVFTMCVWPQLAGRFVGCLHPGKAMSTAMFTYVLELFFCVWCTAYKFVPGGVYARESSHLLLGFIMLCIGLGFLTGSKKDLNSIFEVKSDQKPFFKKSTEYIKLLLWLFVGVGLLGLGLRYRTYEKKLGRGVPKRDFSAMIWPFRFAYDNEGWSNLEGSATLLNQTGADFITVLESDASKPFIGNNDPTMWLGERLGFYTDFGPSTRDHTWGIMALSRYPIVKSTHHLLPSPEGEIAPAISMTVNFTGRLIDFVVAHFGNEEEDLDRKLQAIAVSKLLKTSSKQVVFLGYVTSAPGSRDYTELIENGNVQDIDSTDRDRWCSYIMYRGVIRLGYARISHAGLSDSEVQMAKFRIPDDLDNYVDNDRIVTDPSQVPEDVHFNPRFGSYKDGHNYDESIHHFHMSTPKYFKQTN", "length": 702, "header": "tr|A0A8V0YQ34-1|A0A8V0YQ34_CHICK Isoform 1 of PGAP2-interacting protein OS=Gallus gallus OX=9031 GN=CWH43 PE=3 SV=1 CANONICAL=A0A8V0YQ34-1" }, "locus": { "chromosome": "4", "start_pos": 65767628, "end_pos": 65743985, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010039938.1", "url": "https://www.ensembl.org/id/ENSGALT00010039938.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023125.1", "url": "https://www.ensembl.org/id/ENSGALP00010023125.1" } ] } }, { "isoform_ac": "A0A8V0YWG9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ34/entry#A0A8V0YWG9-1", "sequence": { "sequence": "MIYYFPLQTLALTGLEVFAVAFLSPVFLIVAPCWRLANNKYILALLRLTVVGSLASYQAPNASIRLFILAAGVSSSLLVQTVTLWSGNSLQRFIRIWGFILGKMMLLVLRIWYTSLNPVWSSQAANTVVLIIGLVAAAERIYSVEDERKQGANATGNTVRKAVSQPNWLLSGMAFGSLMFLTVWIFGEVSLISRWAVSGHPHTGPDPNPYGGTVLLGLAHGLMLSFWSWSSVASFAWFLIGIASSAGLLYLHTWSAAVAGNILAVFTMCVWPQLAGRFVGCLHPGKAMSTAMFTYVLELFFCVWCTAYKFVPGGVYARESSHLLLGFIMLCIGLGFLTGSKKDLNSIFEVKSDQKPFFKKSTEYIKLLLWLFVGVGLLGLGLRYRTYEKKLGRGVPKRDFSAMIWPFRFAYDNEGWSNLEGSATLLNQTGADFITVLESDASKPFIGNNDPTMWLGERLGFYTDFGPSTRDHTWGIMALSRYPIVKSTHHLLPSPEGEIAPAISMTVNFTGRLIDFVVAHFGNEEEDLDRKLQAIAVSKLLKTSSKQVVFLGYVTSAPGSRDYTELIENGNVQDIDSTDRDRWCSYIMYRGVIRLGYARISHAGLSDSEVQMAKFRIPDDLDNYVDNDRIVTDPSQVPEDVHFNPRFGSYKDGHNYDESIHHFHMSTPKYFKQTN", "length": 675, "header": "tr|A0A8V0YWG9-1|A0A8V0YWG9_CHICK Computationally mapped isoform of PGAP2-interacting protein OS=Gallus gallus OX=9031 GN=CWH43 PE=3 SV=1 CANONICAL=A0A8V0YQ34-1" }, "locus": { "chromosome": "4", "start_pos": 65766707, "end_pos": 65743985, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010039932.1", "url": "https://www.ensembl.org/id/ENSGALT00010039932.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023121.1", "url": "https://www.ensembl.org/id/ENSGALP00010023121.1" } ] } }, { "isoform_ac": "A0A8V0YWX0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ34/entry#A0A8V0YWX0-1", "sequence": { "sequence": "MDPLWRAVLSESLLGSLASYQAPNASIRLFILAAGVSSSLLVQTVTLWSGNSLQRFIRIWGFILGKMMLLVLRIWYTSLNPVWSSQAANTVVLIIGLVAAAERIYSVEDERKQGANATGNTVRKAVSQPNWLLSGMAFGSLMFLTVWIFGEVSLISRWAVSGHPHTGPDPNPYGGTVLLGLAHGLMLSFWSWSSVASFAWFLIGIASSAGLLYLHTWSAAVAGNILAVFTMCVWPQLAGRFVGCLHPGKAMSTAMFTYVLELFFCVWCTAYKFVPGGVYARESSHLLLGFIMLCIGLGFLTGSKKDLNSIFEVKSDQKPFFKKSTEYIKLLLWLFVGVGLLGLGLRYRTYEKKLGRGVPKRDFSAMIWPFRFAYDNEGWSNLEGSATLLNQTGADFITVLESDASKPFIGNNDPTMWLGERLGFYTDFGPSTRDHTWGIMALSRYPIVKSTHHLLPSPEGEIAPAISMTVNFTGRLIDFVVAHFGNEEEDLDRKLQAIAVSKLLKTSSKQVVFLGYVTSAPGSRDYTELIENGNVQDIDSTDRDRWCSYIMYRGVIRLGYARISHAGLSDSEVQMAKFRIPDDLDNYVDNDRIVTDPSQVPEDVHFNPRFGSYKDGHNYDESIHHFHMSTPKYFKQTN", "length": 638, "header": "tr|A0A8V0YWX0-1|A0A8V0YWX0_CHICK Computationally mapped isoform of PGAP2-interacting protein OS=Gallus gallus OX=9031 GN=CWH43 PE=3 SV=1 CANONICAL=A0A8V0YQ34-1" }, "locus": { "chromosome": "4", "start_pos": 65767628, "end_pos": 65743985, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010039944.1", "url": "https://www.ensembl.org/id/ENSGALT00010039944.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023129.1", "url": "https://www.ensembl.org/id/ENSGALP00010023129.1" } ] } }, { "isoform_ac": "A0A8V0YYF9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ34/entry#A0A8V0YYF9-1", "sequence": { "sequence": "MIYYFPLQTLALTGLEVFAVAFLSPVFLIVAPCWRLANNKYILALLRLTVVGSLASYQAPNASIRLFILAAGVSSSLLVQTVTLWSGNSLQRFIRIWGFILGKMMLLVLRIWYTSLNPVWSSQAANTVVLIIGLVAAAERIYSVEDERKQGANATGNTVRKAVSQPNWLLSGMAFGSLMFLTVWIFGEVSLISRWAVSGHPHTGPDPNPYGGTVLLGLAHGLMLSFWSWSSVASFAWFLIGIASSAGLLYLHTWSAAVAGNILAVFTMCVWPQLAGRFVGCLHPGKAMSTAMFTYVLELFFCVWCTAYKFVPGGVYARESSHLLLGFLTGSKKDLNSIFEVKSDQKPFFKKSTEYIKLLLWLFVGVGLLGLGLRYRTYEKKLGRGVPKRDFSAMIWPFRFAYDNEGWSNLEGSATLLNQTGADFITVLESDASKPFIGNNDPTMWLGERLGFYTDFGPSTRDHTWGIMALSRYPIVKSTHHLLPSPEGEIAPAISMTVNFTGRLIDFVVAHFGNEEEDLDRKLQAIAVSKLLKTSSKQVVFLGYVTSAPGSRDYTELIENGNVQDIDSTDRDRWCSYIMYRGVIRLGYARISHAGLSDSEVQMAKFRIPDDLDNYVDNDRIVTDPSQVPEDVHFNPRFGSYKDGHNYDESIHHFHMSTPKYFKQTN", "length": 666, "header": "tr|A0A8V0YYF9-1|A0A8V0YYF9_CHICK Computationally mapped isoform of PGAP2-interacting protein OS=Gallus gallus OX=9031 GN=CWH43 PE=3 SV=1 CANONICAL=A0A8V0YQ34-1" }, "locus": { "chromosome": "4", "start_pos": 65766707, "end_pos": 65743985, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010039948.1", "url": "https://www.ensembl.org/id/ENSGALT00010039948.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023133.1", "url": "https://www.ensembl.org/id/ENSGALP00010023133.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:422763", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422763", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3Q1MBB4-1", "protein_name": "PGAP2-interacting protein", "gene_name": "CWH43", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MTSPWREVLLESLLGYVSWSLCHDLSPMIYYFPLQTLGLTGLEGFAIAFLSPLFLTITPVWNLVNKKWMLALLRIITVGSIASFQAPNAKLRLTVLALGLSSSLVVHAVTWWTGNGLQRYFRIWGFILGQILLLVLRIWYTSLNPVWTYQMSNRVILTLSTIATLDRIYTDGACYKPQWKKNGEAAKAVASGLNWLLAGAAFGSLMFLTHWIFGEVSLVSRWAVSGHPHPGPDPNPFGGVVLLGLASGLMLSSCSWFPGSSLIWWITGATSAAGLLYLPTWAAAVSGCVLALFTASVWPQVLGHLISSGSSPGKAMTTAMIFYILEVFFCAWCTAFKFVPGGVYARERSDVLLGTVMVIIGLNMLLGQKKRVDFHFQTKNSPKVLFRESEKYVKLFLWLLVGVGLLGLGLRHKTYEKKLGKGAPATEVSAAIWPFRFGFDNDGWSSLERSAQLLNQTGADFITILESDASKPYIGNNDLTMWLGEKLGFYTDFGPSARDHTWGIMVLSRYPIVKSEHHLLPSPEGEIAPAITLTVNVSNKPVDFVVTHFGNHEDDLDRKLQAIAVSKLLKNSSEQVIFLGYITSAPGSRDYLQLIKHGNVKDIDSTDQDRWCEYIMYRGLIRLGYARISHAELSDSEIQVAKFRIPDDPINYRDNQKVVTDHREVPEKIHFNPRFGSYKEGHNFENNHHFHMSTPKYFL", "length": 699 }, "evidence": [ { "id": "A0A8V0YQ34", "url": "https://omabrowser.org/oma/group/A0A8V0YQ34/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "D4A4R9-1", "protein_name": "PGAP2-interacting protein", "gene_name": "Cwh43", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPSLWRAIALETLLGYISWSLYHGLGPMIYYFPLQTLELTGLEVFGVAFLSPILLTIPPFWKLVKKKRALTLLRIITVGSVASFEAPNAKLRLIVLALGVSSSLIVQTVTWWSGSGLQRYLKIWGFILGHILLLVLRIWYTSLNPIWSYQMSNRVILSLSAIAVFDRISTDGDYRNPEGKKPDEAATRRTSLSSWLLPGAAFGSLVFLTHWIFGEVSIVSRWAVSGHPHPGPDPNPFGGAVLLGFASGLMLSGSSWLCDTGLAWWMTGATSAMGLLYLRTWAAAVSGCALAVFTGSMWPQVLGHLMNSGTNPGGAMTTGMSLYVLQVFFCAWCTAFKFVPGGVYARERSDVLLGIIMVIIGLSMLFRPKKNLDFLLQTKNSSKMLLRSTEKYMKLILWLLVGVGLLGLGLRHRTYERKLGHGAPADVVSAAIWPFRFGYDNEGWSNLERSAQLLKQTGADFITILESDASKPYMGNNDLTMWLGEKLGFYTDFGPSTRDHTWGIMVLSRYPIVRSEHHLLPSPEGEIAPAITMTVNISDRLVDFVVTHFGNHEDDLDRKLQAIAVSKLLKNCSNQVIFLGYITSEPGSRDYTQLTKHGHVKDIDSSDRDRWCEYIMYRGLIRLGYARISHAELSDSEIQMAKFRIPDDPFNYRDNQRVVIDHRGVPKNIHFNPRFGSYKEGHNHENNHHFHMNTPKYFV", "length": 699 }, "evidence": [ { "id": "A0A8V0YQ34", "url": "https://omabrowser.org/oma/group/A0A8V0YQ34/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P25618-1", "protein_name": "Protein CWH43", "gene_name": "CWH43", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MLIINGKIIPIAHTICAFSAFFAALVTGYSLHFHKIVTNAHYTYPDEWFPSVSATIGDRYPERSIFQILIALTAFPRFLLLLGHYYLNQSKVCFLVGVLRTVSCGGWVYITSTDDHDIHDIFMITYIVLTLPWDIMITRYSSPLTSKNKGLTATIFFGTLFPMIYWYIQHSVQQRAGAYSIYAYFEWSLILLDIAFDAFAYADFKKIDIVLAFNEKPGNTSFFQIRDSSPINYGEEKSSELQKSGEKKVEKEKPVARSATGSYFRFDSFFYLLTNIFNGFLFWSNVTSLLCSIWHFPLWYMGISGYEAAILGYLGPIFLYLPFVSEAFTQYGVLLGGIIAIGAYIVQMPELRLISVAVGTSITVATFVQNLRYITNAETSFSFALTWLLGLVASVILKMGFYTNNPTWVILDERNGGYNKTALVLTVLFGMLSPYVNSINFEGKRNAQAKSASLIGKLFLAVGFGSLLFGIHQLLTDSSTTIYWAWEGYNESHGPLPWPWGALTCTVMLFASLSSVKFMGKPLVPCLLLLISTAVLSARSITQWPKYIFGGLLYAIAMLWLVPSYFSALGQVQNIWVYVLSFSVYIIFVLAHVWVVAYAFVPMGWVLREKIETVLAFSSTFIIIGALTCKNLNIQLVTMGKKFFIYVFFFAVALLSLTARFVYDIRPTGIPQPYHPDSQLITAGIWTIHFGLDNDMWASEDRMINLIKDMELDVVGLLETDTQRITMGNRDLTSKLAHDLNMYADFGPGPNKHTWGCVLLSKFPIVNSTHHLLPSPVGELAPAIHATLQTYNDTLVDVFVFHSGQEEDEEDRRLQSNYMAKLMGNTTRPAILLSYLVVDPGEGNYNTYVSETSGMHDIDPSDDDRWCEYILYRGLRRTGYARVARGTITDTELQVGKFQVLSEQALVEHSDSMYEYGHMSEPEYEDMKFPDKFLGEGERGHFYHVFDEPRYYL", "length": 953 }, "evidence": [ { "id": "A0A8V0YQ34", "url": "https://omabrowser.org/oma/group/A0A8V0YQ34/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q86I62-1", "protein_name": "Transmembrane protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSTTPINNKGKNYGGGYNKQYLILLLADGILAFVNWSLMVEFISVIWFFPMGFMGFTGWEAALLAIFTPIFLGIGFINRIVSRFNLPIRLVAQLLAFFAIFPWAIDKASIKNDEFGIFSSPHVTKTFFVSVAVALDWLAQCNSFANVKSAVRRERGAYAYALAIVLHAIIRLPYLSINPFMTWSNWIVFGMILVLVAFVILMGENINASDEKKSGAIWSIEHETSSSSTIATGVSFGGIIFFNQLLFSTYGLIPRWVGLNPFPYGLFVILGMMAGVVISKKKHLVTSRNFFIFALILSAIFGWCSGTVPFIVGFIGLISASLLGAYCNSLWIVLIEKVSNTEKLGQLFTSAMLTYTVLLFWAIYVVSYKFVPWWLGSTLLRERNQTLIIACVLATGIAFVYKSLRSSGGSSSSSIKREKSNKDQPSYPNKDVFNILFGLLVLLLLFSVNRAITHPTDSSIAGHHYTRDLTATSVTNTAPTDIKSMIWTIHFGYDNFGRNSFPNVTKVIKDHGANIIGLLESDLSRVMTSNRDLVEWIATELHMYSDFGPEPSRNTWGCALLTIFPIISSDRVILPSPEGELACLIDAVLLIDETPVNVIVTHFGNTEDVLDRKLQTEGAAAIVKKNADMPIIFLSYITTKVNTENYNTLRASGLDDTTNEGRYCQYIFYKNLQLNKFQRFSSFDISDTEQQVASFSVIKENKQQQQQTEQQTQQ", "length": 714 }, "evidence": [ { "id": "A0A8V0YQ34", "url": "https://omabrowser.org/oma/group/A0A8V0YQ34/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q91YL7-1", "protein_name": "PGAP2-interacting protein", "gene_name": "Cwh43", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPGLWRAIALETLLGYVSWSLYHGLSPMIYYFPLQTLELTGLEFFCVAFLSPILLTIPPLWKLVNKKWTLSLLRIVTVGSIASFEAPNAKLRLMVLALGVSSSLIVQTVTWWSGSGLQRYLKIWGFILGHVLLLVLRIWYTSLNPIWSYQMSNRVILTLSAVAVLDRIGTDGDYRNPEGKKPREVATGRTSLSSWLLPGAAFGSLLFLTHWIFGEVSIVSRWAVSGHPHPGPDPNPFGGAVLLGFSSGLMLSGSSWLHDAGLAWWMTGAASAMGLLYLRTWAAAVSGCVLAVFTGSMWPQVLGHLVNSGKNSGEAMATGMILYVLQTFFCAWCTAFKFVPGGVYARERSDVLLGTIMVIIGLSMLFGPKKNLDFLLQTKNSPKTLLRCSEKYMKLILWLFVGVGLLGLGLRHRTYERQLGRGAPATVVSAAIWPFRFGYDNEGWPNLERSAQLLKETGADFITILESDASKPYIGNNDLTMWLGEKLGFYTDFGPSTRDHTWGIMVLSRYPIVRSEHHLLPSPEGEIAPAITMTVNVSNRLVDFVVTHFGNHEDDLDRKLQAIAVSKLLKNCSNQVIFLGYITSEPGSRDYIQLTKHGNVKDIDSSDGDRWCEYIMYRGLIRLGYARISHAELSDSEIQMAKFRIPDDPANYRDNQKVVIDHRGVPKNIHFNPRFGSYKEGHNYENTHHFHMNTPKYFV", "length": 699 }, "evidence": [ { "id": "A0A8V0YQ34", "url": "https://omabrowser.org/oma/group/A0A8V0YQ34/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9H720-1", "protein_name": "PGAP2-interacting protein", "gene_name": "CWH43", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPSLWREILLESLLGCVSWSLYHDLGPMIYYFPLQTLELTGLEGFSIAFLSPIFLTITPFWKLVNKKWMLTLLRIITIGSIASFQAPNAKLRLMVLALGVSSSLIVQAVTWWSGSHLQRYLRIWGFILGQIVLVVLRIWYTSLNPIWSYQMSNKVILTLSAIATLDRIGTDGDCSKPEEKKTGEVATGMASRPNWLLAGAAFGSLVFLTHWVFGEVSLVSRWAVSGHPHPGPDPNPFGGAVLLCLASGLMLPSCLWFRGTGLIWWVTGTASAAGLLYLHTWAAAVSGCVFAIFTASMWPQTLGHLINSGTNPGKTMTIAMIFYLLEIFFCAWCTAFKFVPGGVYARERSDVLLGTMMLIIGLNMLFGPKKNLDLLLQTKNSSKVLFRKSEKYMKLFLWLLVGVGLLGLGLRHKAYERKLGKVAPTKEVSAAIWPFRFGYDNEGWSSLERSAHLLNETGADFITILESDASKPYMGNNDLTMWLGEKLGFYTDFGPSTRYHTWGIMALSRYPIVKSEHHLLPSPEGEIAPAITLTVNISGKLVDFVVTHFGNHEDDLDRKLQAIAVSKLLKSSSNQVIFLGYITSAPGSRDYLQLTEHGNVKDIDSTDHDRWCEYIMYRGLIRLGYARISHAELSDSEIQMAKFRIPDDPTNYRDNQKVVIDHREVSEKIHFNPRFGSYKEGHNYENNHHFHMNTPKYFL", "length": 699 }, "evidence": [ { "id": "A0A8V0YQ34", "url": "https://omabrowser.org/oma/group/A0A8V0YQ34/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQ34", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ34" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQ34", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ34" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "GPI anchor biosynthetic process", "id": "GO:0006506", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006506", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQ34", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ34" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 180, "end_pos": 182, "annotation": "n_glycosylation_sequon" }, { "start_pos": 454, "end_pos": 456, "annotation": "n_glycosylation_sequon" }, { "start_pos": 535, "end_pos": 537, "annotation": "n_glycosylation_sequon" }, { "start_pos": 88, "end_pos": 90, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YQ34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ34" }, { "id": "PF23226", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23226" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PGAP2IP C-terminal nuclease-like", "eco_id": "ECO_0000259", "start_pos": 425, "end_pos": 656, "start_aa": "Arg", "end_aa": "Arg", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0YQ34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ34" }, { "id": "PF23022", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23022" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PGAP2IP first transmembrane", "eco_id": "ECO_0000259", "start_pos": 16, "end_pos": 164, "start_aa": "Tyr", "end_aa": "Ala", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0YQ34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ34" }, { "id": "PF23021", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23021" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PGAP2IP second transmembrane", "eco_id": "ECO_0000259", "start_pos": 192, "end_pos": 369, "start_aa": "Gln", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 180, "end_pos": 182 }, { "start_pos": 454, "end_pos": 456 }, { "start_pos": 535, "end_pos": 537 }, { "start_pos": 88, "end_pos": 90 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YQ47-1", "uniprot_ac": "A0A8V0YQ47", "uniprot_id": "A0A8V0YQ47_CHICK", "mass": { "chemical_mass": 78427.0, "monoisotopic_mass": 78427.0 }, "refseq": {}, "gene_names": [ { "name": "COL8A2", "type": "recommended", "evidence": [ { "id": "A0A8V0YQ47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ47" } ] } ], "protein_names": [ { "name": "Collagen type VIII alpha 2 chain", "type": "synonym", "evidence": [ { "id": "A0A8V0YQ47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ47/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQ47", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ47" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "COL8A2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ47", "locus": { "chromosome": "23", "start_pos": 4505028, "end_pos": 4477504, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010014897", "url": "https://www.ensembl.org/id/ENSGALG00010014897" } ] } } ], "crossref": [ { "id": "A0A8V0YQ47", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YQ47", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR001073", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001073", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008160", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008160", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008983", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008983", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050392", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050392", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YQ38", "url": "https://www.orthodb.org/?gene=A0A8V0YQ38", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YQ43", "url": "https://www.orthodb.org/?gene=A0A8V0YQ43", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YQ47", "url": "https://www.orthodb.org/?gene=A0A8V0YQ47", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YWW3", "url": "https://www.orthodb.org/?gene=A0A8V0YWW3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15427", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15427", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15427:SF53", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15427:SF53", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00386", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00386", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01391", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01391", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YQ38", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ38", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQ38-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ38-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQ43", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ43", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQ43-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ43-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQ47", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ47", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQ47-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ47-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YWW3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YWW3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YWW3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YWW3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKSRRAAALPRRGEAKKGLMLINYHHGSIIARRRETTSKAPCHHVFFKLPKISALCQSVCLHGAGTEHVAGGVVSVQRVFVFHKRTLRAGAAVPTPRGALWSRMLPDAAVLLLLLLLVSLRAAAAGGAAGYAQVKYMQPMVKGPLGPPFREGKGQYLDMPPLLPMDLKGEPGPPGKPGPRGPPGPPGYPGKPGTGKPGMHGQPGPAGPPGFSGIGKPGIPGLPGKAGMKGMPGAKGEPGMRGEQGPRGLPGPPGLPGPAGISVNGKPGPQGGPGLPGFRGEPGPKGEPGPRGERGMKGENGVGKPGLPGPRGNGGPPGPAGPPGPVGVGKPGLDGLPGAPGEKGDMGPPGGPGVSGEPGPAGPRGPPGIDGIGVPGAAGVPGIQGPMGPKGEPGIRGPPGLPGATGYGKPGLPGLKGDRGQPGVPGAIGDKGEPGVDGEPGEQGPAGVIGPPGPPGSMGLPGKHGLPGPKGDVGPSGPPGMPGMRGDQGPNGFAGKPGVPGERGLPGSQGPPGPAGPKGEPGFIGLPGVPGLTGGPGPKGDGGIPGQPGLRGPSGIPGLQGPAGPMGPQGLPGLKGEPGLPGVPGEGKMGEPGMAGPIGPPGMPGTPGLNGPPGPPGPPGPPGAPGVFDETGIAGLHLPDGGVEGAVLGNGKPGKPQYGRGELSARIAPAFTAILTSPFPASGMPVKFDRTLYNGHNGYNPVTGIFTCPISGIYYFAYHVHVKGTNVWVALYKNNVPATYTYDEYKKGYLDQASGSAVLELKENDQVWVQMPSDQANGLYSTEYIHSSFSGFLLCPT", "length": 797, "header": "tr|A0A8V0YQ47-1|A0A8V0YQ47_CHICK Isoform 1 of Collagen type VIII alpha 2 chain OS=Gallus gallus OX=9031 GN=COL8A2 PE=1 SV=1 CANONICAL=A0A8V0YQ47-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YQ38-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ47/entry#A0A8V0YQ38-1", "sequence": { "sequence": "MLRGEHITPCCCCEMQSSETCVCDMPPLLPMDLKGEPGPPGKPGPRGPPGPPGYPGKPGTGKPGMHGQPGPAGPPGFSGIGKPGIPGLPGKAGMKGMPGAKGEPGMRGEQGPRGLPGPPGLPGPAGISVNGKPGPQGGPGLPGFRGEPGPKGEPGPRGERGMKGENGVGKPGLPGPRGNGGPPGPAGPPGPVGVGKPGLDGLPGAPGEKGDMGPPGGPGVSGEPGPAGPRGPPGIDGIGVPGAAGVPGIQGPMGPKGEPGIRGPPGLPGATGYGKPGLPGLKGDRGQPGVPGAIGDKGEPGVDGEPGEQGPAGVIGPPGPPGSMGLPGKHGLPGPKGDVGPSGPPGMPGMRGDQGPNGFAGKPGVPGERGLPGSQGPPGPAGPKGEPGFIGLPGVPGLTGGPGPKGDGGIPGQPGLRGPSGIPGLQGPAGPMGPQGLPGLKGEPGLPGVPGEGKMGEPGMAGPIGPPGMPGTPGLNGPPGPPGPPGPPGAPGVFDETGIAGLHLPDGGVEGAVLGNGKPGKPQYGRGELSARIAPAFTAILTSPFPASGMPVKFDRTLYNGHNGYNPVTGIFTCPISGIYYFAYHVHVKGTNVWVALYKNNVPATYTYDEYKKGYLDQASGSAVLELKENDQVWVQMPSDQANGLYSTEYIHSSFSGFLLCPT", "length": 663, "header": "tr|A0A8V0YQ38-1|A0A8V0YQ47_CHICK Computationally mapped isoform of Collagen type VIII alpha 2 chain OS=Gallus gallus OX=9031 GN=COL8A2 PE=1 SV=1 CANONICAL=A0A8V0YQ47-1" }, "locus": { "chromosome": "23", "start_pos": 4499616, "end_pos": 4496076, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010035840.1", "url": "https://www.ensembl.org/id/ENSGALT00010035840.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020784.1", "url": "https://www.ensembl.org/id/ENSGALP00010020784.1" } ] } }, { "isoform_ac": "A0A8V0YQ43-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ47/entry#A0A8V0YQ43-1", "sequence": { "sequence": "MEVLPTGGTPTWRPDVSPAGCRPSKAPCSLLSADMPPLLPMDLKGEPGPPGKPGPRGPPGPPGYPGKPGTGKPGMHGQPGPAGPPGFSGIGKPGIPGLPGKAGMKGMPGAKGEPGMRGEQGPRGLPGPPGLPGPAGISVNGKPGPQGGPGLPGFRGEPGPKGEPGPRGERGMKGENGVGKPGLPGPRGNGGPPGPAGPPGPVGVGKPGLDGLPGAPGEKGDMGPPGGPGVSGEPGPAGPRGPPGIDGIGVPGAAGVPGIQGPMGPKGEPGIRGPPGLPGATGYGKPGLPGLKGDRGQPGVPGAIGDKGEPGVDGEPGEQGPAGVIGPPGPPGSMGLPGKHGLPGPKGDVGPSGPPGMPGMRGDQGPNGFAGKPGVPGERGLPGSQGPPGPAGPKGEPGFIGLPGVPGLTGGPGPKGDGGIPGQPGLRGPSGIPGLQGPAGPMGPQGLPGLKGEPGLPGVPGEGKMGEPGMAGPIGPPGMPGTPGLNGPPGPPGPPGPPGAPGVFDETGIAGLHLPDGGVEGAVLGNGKPGKPQYGRGELSARIAPAFTAILTSPFPASGMPVKFDRTLYNGHNGYNPVTGIFTCPISGIYYFAYHVHVKGTNVWVALYKNNVPATYTYDEYKKGYLDQASGSAVLELKENDQVWVQMPSDQANGLYSTEYIHSSFSGFLLCPT", "length": 673, "header": "tr|A0A8V0YQ43-1|A0A8V0YQ43_CHICK Computationally mapped isoform of Collagen type VIII alpha 2 chain OS=Gallus gallus OX=9031 GN=COL8A2 PE=1 SV=1 CANONICAL=A0A8V0YQ47-1" }, "locus": { "chromosome": "23", "start_pos": 4499616, "end_pos": 4497598, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010035847.1", "url": "https://www.ensembl.org/id/ENSGALT00010035847.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020789.1", "url": "https://www.ensembl.org/id/ENSGALP00010020789.1" } ] } }, { "isoform_ac": "A0A8V0YQ47-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ47/entry#A0A8V0YQ47-1", "sequence": { "sequence": 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"chromosome": "23", "start_pos": 4499616, "end_pos": 4493245, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010035844.1", "url": "https://www.ensembl.org/id/ENSGALT00010035844.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020787.1", "url": "https://www.ensembl.org/id/ENSGALP00010020787.1" } ] } }, { "isoform_ac": "A0A8V0YWW3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ47/entry#A0A8V0YWW3-1", "sequence": { "sequence": "MPPLLPMDLKGEPGPPGKPGPRGPPGPPGYPGKPGTGKPGMHGQPGPAGPPGFSGIGKPGIPGLPGKAGMKGMPGAKGEPGMRGEQGPRGLPGPPGLPGPAGISVNGKPGPQGGPGLPGFRGEPGPKGEPGPRGERGMKGENGVGKPGLPGPRGNGGPPGPAGPPGPVGVGKPGLDGLPGAPGEKGDMGPPGGPGVSGEPGPAGPRGPPGIDGIGVPGAAGVPGIQGPMGPKGEPGIRGPPGLPGATGYGKPGLPGLKGDRGQPGVPGAIGDKGEPGVDGEPGEQGPAGVIGPPGPPGSMGLPGKHGLPGPKGDVGPSGPPGMPGMRGDQGPNGFAGKPGVPGERGLPGSQGPPGPAGPKGEPGFIGLPGVPGLTGGPGPKGDGGIPGQPGLRGPSGIPGLQGPAGPMGPQGLPGLKGEPGLPGVPGEGKMGEPGMAGPIGPPGMPGTPGLNGPPGPPGPPGPPGAPGVFDETGIAGLHLPDGGVEGAVLGNGKPGKPQYGRGELSARIAPAFTAILTSPFPASGMPVKFDRTLYNGHNGYNPVTGIFTCPISGIYYFAYHVHVKGTNVWVALYKNNVPATYTYDEYKKGYLDQASGSAVLELKENDQVWVQMPSDQANGLYSTEYIHSSFSGFLLCPT", "length": 639, "header": "tr|A0A8V0YWW3-1|A0A8V0YWW3_CHICK Computationally mapped isoform of Collagen type VIII alpha 2 chain OS=Gallus gallus OX=9031 GN=COL8A2 PE=1 SV=1 CANONICAL=A0A8V0YQ47-1" }, "locus": { "chromosome": "23", "start_pos": 4499616, "end_pos": 4497700, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010035850.1", "url": "https://www.ensembl.org/id/ENSGALT00010035850.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020791.1", "url": "https://www.ensembl.org/id/ENSGALP00010020791.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 606, "start_aa": "Thr", "end_pos": 606, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr606", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 95, "start_aa": "Thr", "end_pos": 95, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr95", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQ47", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ47" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YQ47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ47" }, { "id": "PS50871", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50871" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C1q", "eco_id": "ECO_0000259", "start_pos": 664, "end_pos": 797, "start_aa": "Ser", "end_aa": "Thr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 95, 606 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": 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"sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YQ57-1", "uniprot_ac": "A0A8V0YQ57", "uniprot_id": "A0A8V0YQ57_CHICK", "mass": { "chemical_mass": 21358.0, "monoisotopic_mass": 21358.0 }, "refseq": {}, "gene_names": [ { "name": "LOC100857609", "type": "recommended", "evidence": [ { "id": "A0A8V0YQ57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ57" } ] } ], "protein_names": [ { "name": "phosphoinositide phospholipase C", "type": "recommended", "evidence": [ { "id": "A0A8V0YQ57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ57/entry#names_and_taxonomy" } ] }, { "name": "3.1.4.11", "type": "synonym", "evidence": [ { "id": "A0A8V0YQ57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ57/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQ57", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ57" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LOC100857609", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ57", "locus": {} } ], "crossref": [ { "id": "A0A8V0YQ57", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YQ57", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR000980", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000980", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036860", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036860", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051184", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051184", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YQ57", "url": "https://www.orthodb.org/?gene=A0A8V0YQ57", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR19969", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19969", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19969:SF8", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19969:SF8", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00017", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00017", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YQ57", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ57", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQ57-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ57-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVSPQEADCQTVADSITYIWNPIYIVSTGSRRGSRSTQKEVSANIELHLEQDWYHGKLGAGCGGRHIAEQRVMEYCAEMEAPDGSFLVRESGTYVGDYVLSIWWDGKVQHIHIRWQQDADVHRFFLTDNLVFDSLYDLITHYKEMPMSANTGISGFLDLCRRRLFSLPVPYPLHLPPFASNAISNSSL", "length": 188, "header": "tr|A0A8V0YQ57-1|A0A8V0YQ57_CHICK Isoform 1 of phosphoinositide phospholipase C OS=Gallus gallus OX=9031 GN=LOC100857609 PE=4 SV=1 CANONICAL=A0A8V0YQ57-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YQ57-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ57/entry#A0A8V0YQ57-1", "sequence": { "sequence": "MVSPQEADCQTVADSITYIWNPIYIVSTGSRRGSRSTQKEVSANIELHLEQDWYHGKLGAGCGGRHIAEQRVMEYCAEMEAPDGSFLVRESGTYVGDYVLSIWWDGKVQHIHIRWQQDADVHRFFLTDNLVFDSLYDLITHYKEMPMSANTGISGFLDLCRRRLFSLPVPYPLHLPPFASNAISNSSL", "length": 188, "header": "tr|A0A8V0YQ57-1|A0A8V0YQ57_CHICK Isoform 1 of phosphoinositide phospholipase C OS=Gallus gallus OX=9031 GN=LOC100857609 PE=4 SV=1 CANONICAL=A0A8V0YQ57-1" }, "locus": { "chromosome": "13", "start_pos": 14856512, "end_pos": 14854849, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031347.1", "url": "https://www.ensembl.org/id/ENSGALT00010031347.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018281.1", "url": "https://www.ensembl.org/id/ENSGALP00010018281.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "phosphatidylinositol-4,5-bisphosphate phospholipase C activity", "id": "GO:0004435", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004435", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQ57", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ57" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQ57", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ57" } ], "pmid": "" }, { "name": "lipid catabolic process", "id": "GO:0016042", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016042", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQ57", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ57" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 185, "end_pos": 187, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YQ57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ57" }, { "id": "PS50001", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50001" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SH2", "eco_id": "ECO_0000259", "start_pos": 53, "end_pos": 169, "start_aa": "Trp", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "3.1.4.11", "ec_name": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + H2O = 1D-myo-inositol 1,4,5-trisphosphate + a 1,2-diacyl-sn-glycerol + H(+).", "evidence": [ { "id": "3.1.4.11", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.4.11" }, { "id": "3.1.4.11", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=3.1.4.11" } ] } ], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 185, "end_pos": 187 } ] }, 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"MSSDPSSSSSPPRVGSPIPQCTGSAELLRCPSCRLPLWEPVTVSCGHSFCKPCLGGAVPSRCSVCHRRLKLLGVEAVRCNVVLCNLLEKCEERESRSARLAACIRSRLARGDLQDALRMAQKGIEMAPEDKSLRLCRAEALAALRRYPEALQDLEAVCRAEPMECEGFYRKGKVLLEMGRRAEALLAWEHCLVLSPHFQPVQREMEKVLTWEDAPQPCAAQQGSTGHQEEQDEGGPASSSTQAQEEELEAGGGDAVSEHGQGTPVGPRQAPGAAAQREARQEANEEETAATDNLLPLEELLSISDLECSLCIRMFFEPVTTPCGHTFCKECLERCLDHRPNCPLCKQSLREYLKAGSYSPTVLLQDIMLAAFPAQLAERRELHRAEMAELSNLTTNIPIFVCTMSFPGVACPLHIFEPRYRLMIRRCQETGTRRFGMCIYENGKSFADYGCMLEIRQLELLADGRSLVDTIGGRRFRVLRRGHRDGYNTADIEYLEDKKVAGEELQELQSLHESTYQLAQRFWEHGDVASRHLLLQHGSLPEKEEDIQASADGPTWCWWLISILPLDPSFQLRLFSSTSLHARLAQLQRVLLALLQPSPEHSLQGFV", "length": 607, "header": "tr|A0A8V0YQ78-1|A0A8V0YQ78_CHICK Isoform 1 of LON peptidase N-terminal domain and RING finger protein 1 OS=Gallus gallus OX=9031 GN=LOC416263 PE=4 SV=1 CANONICAL=A0A8V0YQ78-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YQ78-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ78/entry#A0A8V0YQ78-1", "sequence": { "sequence": "MSSDPSSSSSPPRVGSPIPQCTGSAELLRCPSCRLPLWEPVTVSCGHSFCKPCLGGAVPSRCSVCHRRLKLLGVEAVRCNVVLCNLLEKCEERESRSARLAACIRSRLARGDLQDALRMAQKGIEMAPEDKSLRLCRAEALAALRRYPEALQDLEAVCRAEPMECEGFYRKGKVLLEMGRRAEALLAWEHCLVLSPHFQPVQREMEKVLTWEDAPQPCAAQQGSTGHQEEQDEGGPASSSTQAQEEELEAGGGDAVSEHGQGTPVGPRQAPGAAAQREARQEANEEETAATDNLLPLEELLSISDLECSLCIRMFFEPVTTPCGHTFCKECLERCLDHRPNCPLCKQSLREYLKAGSYSPTVLLQDIMLAAFPAQLAERRELHRAEMAELSNLTTNIPIFVCTMSFPGVACPLHIFEPRYRLMIRRCQETGTRRFGMCIYENGKSFADYGCMLEIRQLELLADGRSLVDTIGGRRFRVLRRGHRDGYNTADIEYLEDKKVAGEELQELQSLHESTYQLAQRFWEHGDVASRHLLLQHGSLPEKEEDIQASADGPTWCWWLISILPLDPSFQLRLFSSTSLHARLAQLQRVLLALLQPSPEHSLQGFV", "length": 607, "header": "tr|A0A8V0YQ78-1|A0A8V0YQ78_CHICK Isoform 1 of LON peptidase N-terminal domain and RING finger protein 1 OS=Gallus gallus OX=9031 GN=LOC416263 PE=4 SV=1 CANONICAL=A0A8V0YQ78-1" }, "locus": { "chromosome": "13", "start_pos": 11908506, "end_pos": 11899743, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010040012.1", "url": "https://www.ensembl.org/id/ENSGALT00010040012.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023173.1", "url": "https://www.ensembl.org/id/ENSGALP00010023173.1" } ] } }, { "isoform_ac": "A0A8V0YQ83-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ78/entry#A0A8V0YQ83-1", "sequence": { "sequence": "MSSDPSSSSSPPRVGSPIPQCTGSAELLRCPSCRLPLWEPVTVSCGHSFCKPCLGGAVPSRCSVCHRRLKLLGVEAVRCNVVLCNLLEKCEERESRSARLAACIRSRLARGDLQDALRMAQKGIEMAPEDKSLRLCRAEALAALRRYPEALQDLEAVCRAEPMECEGFYRKGKVLLEMGRRAEALLAWEHCLVLSPHFQPVQREMEKVLTWEDAPQPCAAQQGSTGHQEEQDEGGPASSSTQAQEEELEAGGGDAVSEHGQGTPVGPRQAPGAAAQREARQEANEEETAATDNLLPLEELLSISDLECSLCIRMFFEPVTTPCGHTFCKECLERCLDHRPNCPLCKQSLREYLKAGSYSPTVLLQDIMLAAFPAQLAERRELHRAEMAELSNLTTNIPIFVCTMSFPGVACPLHIFEPRYRLMIRRCQETGTRRFGIPLPLSSSFADYGCMLEIRQLELLADGRSLVDTIGGRRFRVLRRGHRDGYNTADIEYLEDKKVAGEELQELQSLHESTYQLAQRFWEHGDVASRHLLLQHGSLPEKEEDIQASADGPTWCWWLISILPLDPSFQLRLFSSTSLHARLAQLQRVLLALLQPSPEHSLQGFV", "length": 606, "header": "tr|A0A8V0YQ83-1|A0A8V0YQ83_CHICK Computationally mapped isoform of LON peptidase N-terminal domain and RING finger protein 1 OS=Gallus gallus OX=9031 GN=LOC416263 PE=4 SV=1 CANONICAL=A0A8V0YQ78-1" }, "locus": { "chromosome": "13", "start_pos": 11908506, "end_pos": 11899743, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010040020.1", "url": "https://www.ensembl.org/id/ENSGALT00010040020.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023178.1", "url": "https://www.ensembl.org/id/ENSGALP00010023178.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQ78", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ78" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQ78", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ78" } ], "pmid": "" }, { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQ78", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ78" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 392, "end_pos": 394, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YQ78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ78" }, { "id": "PS51787", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51787" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Lon N-terminal", "eco_id": "ECO_0000259", "start_pos": 387, "end_pos": 595, "start_aa": "Met", "end_aa": "Leu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0YQ78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ78" }, { "id": "PS50089", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50089" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RING-type", "eco_id": "ECO_0000259", "start_pos": 30, "end_pos": 66, "start_aa": "Cys", "end_aa": "His", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 392, "end_pos": 394 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YQ88-1", "uniprot_ac": "A0A8V0YQ88", "uniprot_id": "A0A8V0YQ88_CHICK", "mass": { "chemical_mass": 79918.0, "monoisotopic_mass": 79918.0 }, "refseq": { "ac": "XP_025011114", "name": "vasorin isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025011114" }, "gene_names": [ { "name": "VASN", "type": "recommended", "evidence": [ { "id": "A0A8V0YQ88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ88" } ] }, { "name": "VASN", "type": "synonym", "evidence": [ { "id": "XP_025011114", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025011114" } ] } ], "protein_names": [ { "name": "Vasorin", "type": "synonym", "evidence": [ { "id": "A0A8V0YQ88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ88/entry#names_and_taxonomy" } ] }, { "name": "vasorin isoform X1", "type": "synonym", "evidence": [ { "id": "XP_025011114", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025011114" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052545.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_025011114.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_025011114", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025011114" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQ88", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ88" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "VASN", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ88", "locus": { "chromosome": "14", "start_pos": 12732909, "end_pos": 12704628, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010016606", "url": "https://www.ensembl.org/id/ENSGALG00010016606" } ] } } ], "crossref": [ { "id": "A0A8V0YQ88", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YQ88", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00054", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00054", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd00063", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00063", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "101749629", "url": "https://www.ncbi.nlm.nih.gov/gene/101749629", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000483", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000483", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000742", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000742", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001611", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001611", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003591", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003591", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003961", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003961", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036116", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036116", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050333", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050333", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "VPQPQDC", "url": "https://omabrowser.org/oma/group/VPQPQDC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YQ88", "url": "https://www.orthodb.org/?gene=A0A8V0YQ88", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YX28", "url": "https://www.orthodb.org/?gene=A0A8V0YX28", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45712", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45712", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45712:SF22", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45712:SF22", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00008", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00008", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13855", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13855", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_025011114", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025011114", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YQ88", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ88", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQ88-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ88-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YX28", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YX28", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YX28-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YX28-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEAARPTCLVCTLPRAAGKGGALSLPPAVGVVLPHEPGHRAWRSWGADTMNQLVLSTLLLLLLLPGQLARACPTGCQCQDPTTILCAARRGHTVPRGLPPSTLSLYVFENGITMLSEDSFAGLPALQLLDLSQNKITSIQKNIFQPLTELVNLDLSSNQLQEITNETFHGLRLLERLYLQKNRIQHIHATAFDTLENLLELKLQNNQLRAVPPLDLPNLLLLDISWNKIPTITPGALHAINIESLKIAGLGLTSLDEELFQPQNNLHELDVSDNLLERVPVVLRRLGSLTKLSLAGNAHISQLPPEDFRGLHNLQELDISNLNINTIPRDFSRFFPRLRAMTAAGNPFNCICQMSWLVQWVNASGVLLRRPEETRCHFPPKNSGKLLHHLQYADFGCPTTTTTTAATTSPPRTTALRPPVPIPTGSRPPPEPSSTTATLQPRAVPFSSTPVPFSLTPAASSPQPQLCPPRTCLNGGTCQLGARGHLRCLCPPGFAGAFCEEEEEEEEEEEAAARGTTLSPATPAAPPSRKISITQVSSTSLRVDLQNYMQSKAQLRGIRLSYRNLSGPEKRPVMLRLPATLSEYTVRALKPNCTYRVCVGPLGEKGSKEEFCVEAHTLPASHQQHSPVTQSKDNNLALMIVPALAAVLLLVVVVTAVTYYRRHRRAKEHAGGGVEAGPLELEGVKACLENGERGGHGCRGTENAVLAGGPECEVPLMQAHYPSNNNSAALKPSYF", "length": 735, "header": "tr|A0A8V0YQ88-1|A0A8V0YQ88_CHICK Isoform 1 of Vasorin OS=Gallus gallus OX=9031 GN=VASN PE=1 SV=1 CANONICAL=A0A8V0YQ88-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YQ88-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ88/entry#A0A8V0YQ88-1", "sequence": { "sequence": "MEAARPTCLVCTLPRAAGKGGALSLPPAVGVVLPHEPGHRAWRSWGADTMNQLVLSTLLLLLLLPGQLARACPTGCQCQDPTTILCAARRGHTVPRGLPPSTLSLYVFENGITMLSEDSFAGLPALQLLDLSQNKITSIQKNIFQPLTELVNLDLSSNQLQEITNETFHGLRLLERLYLQKNRIQHIHATAFDTLENLLELKLQNNQLRAVPPLDLPNLLLLDISWNKIPTITPGALHAINIESLKIAGLGLTSLDEELFQPQNNLHELDVSDNLLERVPVVLRRLGSLTKLSLAGNAHISQLPPEDFRGLHNLQELDISNLNINTIPRDFSRFFPRLRAMTAAGNPFNCICQMSWLVQWVNASGVLLRRPEETRCHFPPKNSGKLLHHLQYADFGCPTTTTTTAATTSPPRTTALRPPVPIPTGSRPPPEPSSTTATLQPRAVPFSSTPVPFSLTPAASSPQPQLCPPRTCLNGGTCQLGARGHLRCLCPPGFAGAFCEEEEEEEEEEEAAARGTTLSPATPAAPPSRKISITQVSSTSLRVDLQNYMQSKAQLRGIRLSYRNLSGPEKRPVMLRLPATLSEYTVRALKPNCTYRVCVGPLGEKGSKEEFCVEAHTLPASHQQHSPVTQSKDNNLALMIVPALAAVLLLVVVVTAVTYYRRHRRAKEHAGGGVEAGPLELEGVKACLENGERGGHGCRGTENAVLAGGPECEVPLMQAHYPSNNNSAALKPSYF", "length": 735, "header": "tr|A0A8V0YQ88-1|A0A8V0YQ88_CHICK Isoform 1 of Vasorin OS=Gallus gallus OX=9031 GN=VASN PE=1 SV=1 CANONICAL=A0A8V0YQ88-1" }, "locus": { "chromosome": "14", "start_pos": 12718423, "end_pos": 12715856, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010040025.1", "url": "https://www.ensembl.org/id/ENSGALT00010040025.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023183.1", "url": "https://www.ensembl.org/id/ENSGALP00010023183.1" } ] } }, { "isoform_ac": "A0A8V0YX28-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ88/entry#A0A8V0YX28-1", "sequence": { "sequence": "MNQLVLSTLLLLLLLPGQLARACPTGCQCQDPTTILCAARRGHTVPRGLPPSTLSLYVFENGITMLSEDSFAGLPALQLLDLSQNKITSIQKNIFQPLTELVNLDLSSNQLQEITNETFHGLRLLERLYLQKNRIQHIHATAFDTLENLLELKLQNNQLRAVPPLDLPNLLLLDISWNKIPTITPGALHAINIESLKIAGLGLTSLDEELFQPQNNLHELDVSDNLLERVPVVLRRLGSLTKLSLAGNAHISQLPPEDFRGLHNLQELDISNLNINTIPRDFSRFFPRLRAMTAAGNPFNCICQMSWLVQWVNASGVLLRRPEETRCHFPPKNSGKLLHHLQYADFGCPTTTTTTAATTSPPRTTALRPPVPIPTGSRPPPEPSSTTATLQPRAVPFSSTPVPFSLTPAASSPQPQLCPPRTCLNGGTCQLGARGHLRCLCPPGFAGAFCEEEEEEEEEEEAAARGTTLSPATPAAPPSRKISITQVSSTSLRVDLQNYMQSKAQLRGIRLSYRNLSGPEKRPVMLRLPATLSEYTVRALKPNCTYRVCVGPLGEKGSKEEFCVEAHTLPASHQQHSPVTQSKDNNLALMIVPALAAVLLLVVVVTAVTYYRRHRRAKEHAGGGVEAGPLELEGVKACLENGERGGHGCRGTENAVLAGGPECEVPLMQAHYPSNNNSAALKPSYF", "length": 686, "header": "tr|A0A8V0YX28-1|A0A8V0YX28_CHICK Computationally mapped isoform of Vasorin OS=Gallus gallus OX=9031 GN=VASN PE=1 SV=1 CANONICAL=A0A8V0YQ88-1" }, "locus": { "chromosome": "14", "start_pos": 12718423, "end_pos": 12716366, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010040035.1", "url": "https://www.ensembl.org/id/ENSGALT00010040035.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023192.1", "url": "https://www.ensembl.org/id/ENSGALP00010023192.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 522, "start_aa": "Thr", "end_pos": 522, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr522", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A8DZ86-1", "protein_name": "Vasorin", "gene_name": "vasna", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MRPLSPLSHLILLQLLCGCLSSRCPHDCTCLPNNNIFCVQRNLIYMPRGLPSTGKQLYVFQNKINILQQQDFVELGELEMLDLSQNSLSEIPDGVFSPLSSLHNLDLSSNYITHISKDSFIGLVNLERLYLYSNIIQNIHPAAFEGLENLLELKLQGNQISVLPALQLPRLLHLDLSYNSIPPLVAQDLQTPHLESLKIAGLGLTSLDEELLGSLVNLHVLDVSQNQLVDIQPTLKSMGGLRNLNLTGNPLGSLKHEDFQNLVNLLELDLSNLNLQGFPEGFFNLFPKLEKLTAAENPFNCLCPLAWFPAWLKDVRVELLRTEETRCHFPPINSGKVLEKLEHKDFGCPTTTIELTSAGTSSTTSKPKNSSTQLGTTHIVPPAPPSDISSADADNFPVYQTTAFPSRIMEDSEGEGIMCPPNICLNGGTCIFKSNGVIVCLCPPSMSGNYCEIQNEAMLPPPSPRVSLETIATVQPNTISSHHITSTSISLDLHRYIQTRPHIRGIRLTYSNLSGPDRRPLQLSVPPSYPEYTLRGLQPNSTYSVCASPLGEPVHASVSACMEARTAGIPPSSHEPSVDRTEPSSSLTPIVVAVAVVMVVAIIATVVVISRRRRPKAPVDMDLHETSPLEMEGVKTNPENGLTHPKQPDITPCSSLAPNSLEYDVLLIQGQGQCPANNNIDCTKALYV", "length": 688 }, "evidence": [ { "id": "A0A8V0YQ88", "url": "https://omabrowser.org/oma/group/A0A8V0YQ88/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "D3ZAE6-1", "protein_name": "Vasorin", "gene_name": "Vasn", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MHSRSCLPPLLLLLLVLLGSGVQSCPSGCQCNQPQTVFCTARQGTTVPRDVPPDTVGLYIFENGITTLDVGCFAGFPGLQLLDLSQNQITSLPGGIFQPLVNLSNLDLTANKLHEISNETFRGLRRLERLYLGKNRIRHIQPGAFDALDHLLELKLPDNELRVLPPLHLPRLLLLDLSHNSIPALEAGILDTANVEALRLAGLGLRQLDEGLFGRLRNLHDLDVSDNQLGHMPSVIQGLRGLTRLRLAGNTRIAQIRPEDLAGLTALQELDVSNLSLQALPSDLSSLFPRLRLLAAARNPFNCLCPLSWFGPWVRESHVVLASPEETRCHFPPKNAGRLLLELDYADFGCPVTTTTATVPTIRPTVREPTPSTSSQAPTWPSPTEPTTQAPIVLSTAPPTMRPAPQPQDCPASICLNGGSCRVGAKHHLECLCPEGFIGLYCESPVEQRTKPSSIPDTPRPPRLLPLRIEPVSPTSLRVELQRYLQGNTVQLRSLRLTYRNLSGPDKRLVTLRLPASLAEYTVTQLRPNATYSICVTALGAGRTPEGEEACGEANTPQAVRSNHAPVTQAREGNLPLLIAPALAAVLLAVLAASGAVYCVRRARASSTAQDKGQVGPGTGPLELEGVKVPLEPGSKASEGGGEALSGGPECEVPLMGYPGPSLQGVLPAQPYI", "length": 673 }, "evidence": [ { "id": "A0A8V0YQ88", "url": "https://omabrowser.org/oma/group/A0A8V0YQ88/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3HS71-1", "protein_name": "Vasorin", "gene_name": "Vasn", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MHSRSCLPPLLLLLLLLGESGVQGCPSGCQCNQPQTVFCTARQGTTVPRDVPPDTVGLYIFENGITTLDVGSFAGLPGLQLLDLSQNQITSLPGGIFQPLVNLSNLDLTANKLHEISNETFRGLRRLERLYLGKNRIRHIQPGAFDALDHLLELKLEDNELRLLPPLHLPRLLLLDLSYNNIPALESGVLHTANVEALRLAGLGLRQLDEGLFGRLRNLHDLDVSDNQLEHMPSVIQGLRGLTRLRLAGNTRIAHIRPEDLAGLTALQELDVSNLSLQALPSDLSNLFPRLRLLAAARNPFNCLCPLSWFGPWVRESHVVLASPEETRCHFPPKNAGRLLLDLDYADFGCPVTTTTATVPTIRPTIRESTLSPSNRASTWPSLTEPTTQASTSPSTAPPTMRPVPQPQDCPASTCLNGGTCRVGARHHRECLCPEGFIGLYCESPVRQGMKPSSIPDTPRPPRPLPLSIEPVSPTSLRVGLQRYLQGNTVQLRSLRLTYRNLSGPDKRLVTLRLPASLAEYTVTQLRPNATYSICVTPLGAGRIPEGEEACGEASTPQAVRSNHAPVTQAREGNLPLLIAPALAAVLLAVLAAAGAAYCVRRGRTTVTAQDKGQVGPGTGPLELEGVKAPLEPSSKATEGVGEALSGGPECEVPLMGYSGPSLQGPLPAKHYI", "length": 673 }, "evidence": [ { "id": "A0A8V0YQ88", "url": "https://omabrowser.org/oma/group/A0A8V0YQ88/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "I3LS87-1", "protein_name": "Vasorin", "gene_name": "VASN", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MPPTISPPLLLPLLLLLLLALEPRVQGCPSGCQCNQPQTVFCTARQGTTVPLDVPPDTVGLYIFENGITTIDTGSFAGLPGLQLLDLSQNQITSLPGGVFQPLANLSNLDLTANRLREITNETFRGLRRLERLYLGKNRIRHIQPGAFDALEHLLELKLQDNELRALPPLRLPRLLLLDLSHNSLPALEPGVLDTANVEALRLAGLGLQQLDEGLLGRLRNLHDLDVADNQLERVPPAIRGLRGLTRLRLAGNTRIAQLRPEDLAGLAALQELDLSNLSLQVLPHELSILFPRLRLLAAARNPFNCVCPLSWFGPWVRESRVALTSPEETRCHFPPKNAGRLLLDLDYADFGCPATTTTATVPATRPTVGEPTFPPSSPAPTWLSPTEPATVAPSLPPPAPPTEGPAPQPQDCPASICLNGGTCHLEARGHLECLCPEGFTGLYCESRVRQGPRPSSAPATLQPPRPLPLSIEPVSPTSLRVGLQRYLQGSPLQLRSLRLTYRNLSGPDKRPVTLRLPASLAEYTVTQLRPNATYSICVRPLGAGRMPEGEEACGEARTPPAVRSNHAPVTQAREGNLPLLIAPTLAAVLLAVLAAVGAAFCVRRGRAAAAVAQGKGQVGPGAGPLELEGVKAPLEPGPKGTEGGGEAPPGGPECEVPLMGYSGPGPQGPLPTKPYI", "length": 677 }, "evidence": [ { "id": "A0A8V0YQ88", "url": "https://omabrowser.org/oma/group/A0A8V0YQ88/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q6EMK4-1", "protein_name": "Vasorin", "gene_name": "VASN", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MCSRVPLLLPLLLLLALGPGVQGCPSGCQCSQPQTVFCTARQGTTVPRDVPPDTVGLYVFENGITMLDAGSFAGLPGLQLLDLSQNQIASLPSGVFQPLANLSNLDLTANRLHEITNETFRGLRRLERLYLGKNRIRHIQPGAFDTLDRLLELKLQDNELRALPPLRLPRLLLLDLSHNSLLALEPGILDTANVEALRLAGLGLQQLDEGLFSRLRNLHDLDVSDNQLERVPPVIRGLRGLTRLRLAGNTRIAQLRPEDLAGLAALQELDVSNLSLQALPGDLSGLFPRLRLLAAARNPFNCVCPLSWFGPWVRESHVTLASPEETRCHFPPKNAGRLLLELDYADFGCPATTTTATVPTTRPVVREPTALSSSLAPTWLSPTEPATEAPSPPSTAPPTVGPVPQPQDCPPSTCLNGGTCHLGTRHHLACLCPEGFTGLYCESQMGQGTRPSPTPVTPRPPRSLTLGIEPVSPTSLRVGLQRYLQGSSVQLRSLRLTYRNLSGPDKRLVTLRLPASLAEYTVTQLRPNATYSVCVMPLGPGRVPEGEEACGEAHTPPAVHSNHAPVTQAREGNLPLLIAPALAAVLLAALAAVGAAYCVRRGRAMAAAAQDKGQVGPGAGPLELEGVKVPLEPGPKATEGGGEALPSGSECEVPLMGFPGPGLQSPLHAKPYI", "length": 673 }, "evidence": [ { "id": "A0A8V0YQ88", "url": "https://omabrowser.org/oma/group/A0A8V0YQ88/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9CZT5-1", "protein_name": "Vasorin", "gene_name": "Vasn", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MHSRSCLPPLLLLLLVLLGSGVQGCPSGCQCNQPQTVFCTARQGTTVPRDVPPDTVGLYIFENGITTLDVGCFAGLPGLQLLDLSQNQITSLPGGIFQPLVNLSNLDLTANKLHEISNETFRGLRRLERLYLGKNRIRHIQPGAFDALDRLLELKLPDNELRVLPPLHLPRLLLLDLSHNSIPALEAGILDTANVEALRLAGLGLRQLDEGLFGRLLNLHDLDVSDNQLEHMPSVIQGLRGLTRLRLAGNTRIAQIRPEDLAGLTALQELDVSNLSLQALPSDLSSLFPRLRLLAAARNPFNCLCPLSWFGPWVRENHVVLASPEETRCHFPPKNAGRLLLDLDYADFGCPVTTTTATVPTIRSTIREPTLSTSSQAPTWPSLTEPTTQASTVLSTAPPTMRPAPQPQDCPASICLNGGSCRLGARHHWECLCPEGFIGLYCESPVEQGMKPSSIPDTPRPPPLLPLSIEPVSPTSLRVKLQRYLQGNTVQLRSLRLTYRNLSGPDKRLVTLRLPASLAEYTVTQLRPNATYSICVTPLGAGRTPEGEEACGEANTSQAVRSNHAPVTQAREGNLPLLIAPALAAVLLAVLAAAGAAYCVRRARATSTAQDKGQVGPGTGPLELEGVKAPLEPGSKATEGGGEALSGGPECEVPLMGYPGPSLQGVLPAKHYI", "length": 673 }, "evidence": [ { "id": "A0A8V0YQ88", "url": "https://omabrowser.org/oma/group/A0A8V0YQ88/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQ88", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ88" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQ88", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ88" } ], "pmid": "" }, { "name": "cell surface", "id": "GO:0009986", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009986", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQ88", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ88" } ], "pmid": "" }, { "name": "extracellular exosome", "id": "GO:0070062", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070062", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQ88", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ88" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "transforming growth factor beta binding", "id": "GO:0050431", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050431", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQ88", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ88" } ], "pmid": "" }, { "name": "signaling receptor activity", "id": "GO:0038023", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038023", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQ88", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQ88" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "negative regulation of transforming growth factor beta receptor signaling pathway", "id": "GO:0030512", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030512", 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"count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YQA1-1", "uniprot_ac": "A0A8V0YQA1", "uniprot_id": "A0A8V0YQA1_CHICK", "mass": { "chemical_mass": 43363.0, "monoisotopic_mass": 43363.0 }, "refseq": {}, "gene_names": [ { "name": "FHL1", "type": "recommended", "evidence": [ { "id": "A0A8V0YQA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQA1" } ] } ], "protein_names": [ { "name": "Four and a half LIM domains protein 1", "type": "recommended", "evidence": [ { "id": "A0A8V0YQA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQA1/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "May have an involvement in muscle development or hypertrophy. 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"glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "FHL1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQA1", "locus": { "chromosome": "4", "start_pos": 4189517, "end_pos": 4157456, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010014929", "url": "https://www.ensembl.org/id/ENSGALG00010014929" } ] } } ], "crossref": [ { "id": "A0A8V0YQA1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YQA1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000006190", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000006190", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd09344", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09344", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd09348", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09348", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd09424", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09424", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd09429", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09429", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "770787", "url": "https://www.ncbi.nlm.nih.gov/gene/770787", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001781", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001781", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042997", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042997", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056807", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056807", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:770787", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:770787", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YQA1", "url": "https://www.orthodb.org/?gene=A0A8V0YQA1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YQA2", "url": "https://www.orthodb.org/?gene=A0A8V0YQA2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YS00", "url": "https://www.orthodb.org/?gene=A0A8V0YS00", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NED9", "url": "https://www.orthodb.org/?gene=F1NED9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47029", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47029", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47029:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47029:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00412", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00412", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25076", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25076", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YQA1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQA1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQA1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQA1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQA2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQA2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQA2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQA2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YS00", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YS00", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YS00-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YS00-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NED9", "url": "https://www.uniprot.org/uniprotkb/F1NED9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NED9-1", "url": "https://www.uniprot.org/uniprotkb/F1NED9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLAKCHRWLGFFPPQSAGAEALGGAGCSPPPPAAPWAGPVLLAGLIFFATRLPAISVKAAAVQPGAGGSALDRSSPTSCPQPQHSCTGSVLHPFPAPGSSAARPSSYSVGTMSERFDCHYCRDSLQGKKYVQKEGRHCCVKCFEKICANTCIECKKPIGADSKELHFKNRYWHDSCFRCFKCYTSLVNEPFMLRENNKVWCSNCTATDEAPRCKGCFKPIIAGDQNVEYKKMVWHKDCFTCSQCKQVIGSGSFFPKGDEFYCVSCHEHKFAKTCAKCKNPITSGGLTYQEQPWHSECFICSNCKKQLGGKRFTAVEDQFYCVECYKECVAKKCAGCKNPITGFGRGTSVVNYEDESWHDYCFKCTKCARGLANKRFVCHNGKIYCAECPKRL", "length": 392, "header": "tr|A0A8V0YQA1-1|A0A8V0YQA1_CHICK Isoform 1 of Four and a half LIM domains protein 1 OS=Gallus gallus OX=9031 GN=FHL1 PE=1 SV=1 CANONICAL=A0A8V0YQA1-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YQA1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQA1/entry#A0A8V0YQA1-1", "sequence": { "sequence": "MLAKCHRWLGFFPPQSAGAEALGGAGCSPPPPAAPWAGPVLLAGLIFFATRLPAISVKAAAVQPGAGGSALDRSSPTSCPQPQHSCTGSVLHPFPAPGSSAARPSSYSVGTMSERFDCHYCRDSLQGKKYVQKEGRHCCVKCFEKICANTCIECKKPIGADSKELHFKNRYWHDSCFRCFKCYTSLVNEPFMLRENNKVWCSNCTATDEAPRCKGCFKPIIAGDQNVEYKKMVWHKDCFTCSQCKQVIGSGSFFPKGDEFYCVSCHEHKFAKTCAKCKNPITSGGLTYQEQPWHSECFICSNCKKQLGGKRFTAVEDQFYCVECYKECVAKKCAGCKNPITGFGRGTSVVNYEDESWHDYCFKCTKCARGLANKRFVCHNGKIYCAECPKRL", "length": 392, "header": "tr|A0A8V0YQA1-1|A0A8V0YQA1_CHICK Isoform 1 of Four and a half LIM domains protein 1 OS=Gallus gallus OX=9031 GN=FHL1 PE=1 SV=1 CANONICAL=A0A8V0YQA1-1" }, "locus": { "chromosome": "4", "start_pos": 4187184, "end_pos": 4162855, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010035913.1", "url": "https://www.ensembl.org/id/ENSGALT00010035913.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020838.1", "url": "https://www.ensembl.org/id/ENSGALP00010020838.1" } ] } }, { "isoform_ac": "A0A8V0YQA2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQA1/entry#A0A8V0YQA2-1", "sequence": { "sequence": "MSERFDCHYCRDSLQGKKYVQKEGRHCCVKCFEKICANTCIECKKPIGADSKELHFKNRYWHDSCFRCFKCYTSLVNEPFMLRENNKVWCSNCTATDEAPRCKGCFKPIIAGDQNVEYKKMVWHKDCFTCSQCKQVIGSGSFFPKGDEFYCVSCHEHKFAKTCAKCKNPITSGGLTYQEQPWHSECFICSNCKKQLGGKRFTAVEDQFYCVECYKECVAKKCAGCKNPITAGFGRGTSVVNYEDESWHDYCFKCTKCARGLANKRFVCHNGKIYCAECPKRL", "length": 282, "header": "tr|A0A8V0YQA2-1|A0A8V0YQA2_CHICK Computationally mapped isoform of Four and a half LIM domains protein 1 OS=Gallus gallus OX=9031 GN=FHL1 PE=1 SV=1 CANONICAL=A0A8V0YQA1-1" }, "locus": { "chromosome": "4", "start_pos": 4187184, "end_pos": 4183537, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010035917.1", "url": "https://www.ensembl.org/id/ENSGALT00010035917.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020840.1", "url": "https://www.ensembl.org/id/ENSGALP00010020840.1" } ] } }, { "isoform_ac": "A0A8V0YS00-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQA1/entry#A0A8V0YS00-1", "sequence": { "sequence": "MGTEGTGPSSYSVGTMSERFDCHYCRDSLQGKKYVQKEGRHCCVKCFEKICANTCIECKKPIGADSKELHFKNRYWHDSCFRCFKCYTSLVNEPFMLRENNKVWCSNCTATDEAPRCKGCFKPIIAGDQNVEYKKMVWHKDCFTCSQCKQVIGSGSFFPKGDEFYCVSCHEHKFAKTCAKCKNPITSGGLTYQEQPWHSECFICSNCKKQLGGKRFTAVEDQFYCVECYKECVAKKCAGCKNPITGFGRGTSVVNYEDESWHDYCFKCTKCARGLANKRFVCHNGKIYCAECPKRL", "length": 296, "header": "tr|A0A8V0YS00-1|A0A8V0YS00_CHICK Computationally mapped isoform of Four and a half LIM domains protein 1 OS=Gallus gallus OX=9031 GN=FHL1 PE=1 SV=1 CANONICAL=A0A8V0YQA1-1" }, "locus": { "chromosome": "4", "start_pos": 4187184, "end_pos": 4180707, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010035909.1", "url": "https://www.ensembl.org/id/ENSGALT00010035909.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020834.1", "url": "https://www.ensembl.org/id/ENSGALP00010020834.1" } ] } }, { "isoform_ac": "F1NED9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQA1/entry#F1NED9-1", "sequence": { "sequence": "MAFHRHTGPSSYSVGTMSERFDCHYCRDSLQGKKYVQKEGRHCCVKCFEKICANTCIECKKPIGADSKELHFKNRYWHDSCFRCFKCYTSLVNEPFMLRENNKVWCSNCTATDEAPRCKGCFKPIIAGDQNVEYKKMVWHKDCFTCSQCKQVIGSGSFFPKGDEFYCVSCHEHKFAKTCAKCKNPITSGGLTYQEQPWHSECFICSNCKKQLGGKRFTAVEDQFYCVECYKECVAKKCAGCKNPITGFGRGTSVVNYEDESWHDYCFKCTKCARGLANKRFVCHNGKIYCAECPKRL", "length": 297, "header": "tr|F1NED9-1|F1NED9_CHICK Computationally mapped isoform of Four and a half LIM domains protein 1 OS=Gallus gallus OX=9031 GN=FHL1 PE=1 SV=3 CANONICAL=A0A8V0YQA1-1" }, "locus": { "chromosome": "4", "start_pos": 4187184, "end_pos": 4178022, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010035911.1", "url": "https://www.ensembl.org/id/ENSGALT00010035911.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020836.1", "url": "https://www.ensembl.org/id/ENSGALP00010020836.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:770787", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:770787", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQA1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQA1" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQA1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQA1" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQA1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQA1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQA1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQA1" } ], "pmid": "" }, { "name": "transmembrane transporter binding", "id": "GO:0044325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044325", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQA1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQA1" } ], "pmid": "" }, { "name": "potassium channel activator activity", "id": "GO:0099104", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099104", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQA1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQA1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 7, "go_terms": [ { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQA1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQA1" } ], "pmid": "" }, { "name": "muscle organ development", "id": "GO:0007517", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007517", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQA1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQA1" } ], "pmid": "" }, { "name": "negative regulation of cell growth", "id": "GO:0030308", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030308", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQA1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQA1" } ], "pmid": "" }, { "name": "positive regulation of potassium ion transmembrane transport", "id": "GO:1901381", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901381", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQA1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQA1" } ], "pmid": "" }, { "name": "negative regulation of G1/S transition of mitotic cell cycle", "id": "GO:2000134", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000134", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQA1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQA1" } ], "pmid": "" }, { "name": "negative regulation of G2/M transition of mitotic cell cycle", "id": "GO:0010972", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010972", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQA1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQA1" } ], "pmid": "" }, { "name": "regulation of atrial cardiac muscle cell membrane depolarization", "id": "GO:0060371", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060371", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQA1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQA1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 203, "end_pos": 205, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YQA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQA1" }, { "id": "PS50023", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50023" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "LIM zinc-binding", "eco_id": "ECO_0000259", "start_pos": 149, "end_pos": 210, "start_aa": "Asn", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 203, "end_pos": 205 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": 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"publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YQA9-1", "uniprot_ac": "A0A8V0YQA9", "uniprot_id": "A0A8V0YQA9_CHICK", "mass": { "chemical_mass": 339632.0, "monoisotopic_mass": 339632.0 }, "refseq": {}, "gene_names": [ { "name": "FRYL", "type": "recommended", "evidence": [ { "id": "A0A8V0YQA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQA9" } ] } ], "protein_names": [ { "name": "FRY like transcription coactivator", "type": "synonym", "evidence": [ { "id": "A0A8V0YQA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQA9/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQA9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQA9" } ], "common_name": 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"IPR029473", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029473", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039867", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039867", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045842", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045842", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YQA9", "url": "https://www.orthodb.org/?gene=A0A8V0YQA9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YWM8", "url": "https://www.orthodb.org/?gene=A0A8V0YWM8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YX13", "url": "https://www.orthodb.org/?gene=A0A8V0YX13", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z3Q1", "url": "https://www.orthodb.org/?gene=A0A8V0Z3Q1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12295", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12295", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12295:SF9", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12295:SF9", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF14222", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14222", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14225", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14225", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14228", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14228", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF19421", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19421", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YQA9", "url": 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"database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSNITIDPDVKPGEYVIKSLFAEFAVQAEKKIEVVMAEPLEKLLSRSLQRGEDLQFDQLISSMSSVAEHCLPSLLRTLFDWYRRQNGTEDESYEYRPRSSTKSKGDDQQRERDYLLERRDLAVDFIFCLVLIEVLKQIPVHPVPDPLVHEVLNLAFKHFKHKEGYSGTNTGNVHIIADLYAEVTGVLAQSKFQAVRKKFVTELKELRQKEQSPHVVQSIISLIMGMKFFRVKMYPVEDFEASFQFMQECAQYFLEVKDKDIKHALAGLFVEILIPVAAAVKNEVNVPCLKNFVEMLYQTTFDLSSRKKHSLALYPLITCLLCVSQKQFFLNNWHVFLQNCLSHLKNKDPKMSRVALESLYRLLWVYVIRIKCESNTVTQSRLMSIVSALFPKGSRSVVPRDTPLNIFVKIIQFIAQERLDFAMKEIIFDLLSVGKSPKTFTINPERMNIGLRVFLVIADSLQQKDGEPPMPTTGVVLPSGNTLRVKKIFLNKTLTDEEAKVIGMSIYYPQVRKALDSILRHLDKEVGRPMCMTSVQMSNKEPEDMITGERKPKIDLFRTCIAAIPRLIPDGMSRTDLIELLARLTIHMDEELRALAFNTLQALMLDFPDWREDVLSGFVYFIVREVTDIHPTLLDNAVKMLVQLINQWKQAAQMHNKTQDSQRGVSSGAAHTLPLERTLYSNVFHVVEGFALVILCSTRPATRRLAVSVLREIRALFTLLEISKSDDELAIDVMDRQSASILESFIHLTGADQTTLLYCPSSVDLQTLADWSSSPISHQFDVVSPSHIWIFAHVTQGQDPWIISLSSFMKQENLPKHCPTAVSYAWMFAYTRLQMLSPQVDINSPINAKKVNTTTSSDSYIGLWRNYLILCCSAASSSSSSTSTGSVRCSPPETLASTPDSGYSIDSRIIGIPSPSSLFKHIVPMMRSESMEITESLVLGLGRTNPGAFRELIEELHPIIKEALERRPENMKRRRRRDILRVQLVRIFELLADAGVISHSASGGLDNETHSLNNTLLEYVDLTRQLLEAENEKDSDTLKDIRCHFSALVANIIQNVPVHQRRSVFPQQSLRHSLFMLFSHWAGPFSIMFTPLDRYSDRNMQINRHQYCALKAMSAVLCCGPVADNVGLSSDGYLYKWLDNILDSQDKKVHQLGCEAVTLLLELNPDQSNLMYWAVDRCYTGSKRVAAGCFKAIASVFQNRDYQCDTVTLLNLILFKAADSTRAIYEVAMQLLQILEPKMFRYAHKLEVQRTDGVLGQPSPLPHLYSVSYYQLSEELARTYPELTLAIFSEVSQRIQTAHPAGRQVMLHYLLPWMNNIELVDLKPLPTIRRQDEDEEDSLKDREIMVNSRRWLRGEGWGSPQATAMVLNNLMYMTAKYGDEVAWSEIENVWTTLADSWPKNLKIILHFLISICGVNSEPSLLPYVKKVIVYLGRDKTMQLLEELVSELQLTDPVSSGVTHMDNPPYYRITSSYKIPSVTSGTTSSSNTMVAPTDGNPDSKHIKDSIEENYAHLDIYSGLNSNLNRQHHRLESRYSSSSGGSYEEEKSDSMPLYSNWRLKVMEHNQGEPLPFPPTGGCWSPLVDYLPETTSPGMSLHRCNIAVILLTDLIVDHSVKVEWGGYLHLLLHAIFIGFDHCHPEVYEHCKRLLLHLLIVMGSGSNVQSVASVLLRNREFNESRMLTVKQTTHLDYTFTAGVHDFIPDYQPSPMTDSGLSSSSTSSSISLGNTSAAMSHMHTTILNEVDISVEQDEKVKTLIEFITSRKRGPLWNHEDVSAKNPSIKSAEQLTVFLKHVVSIFKQSSSGGFQLEHCLSEVALQTALSCSSRHYAGRSFQIFRALKQPLTASTLSDVLSRLVETVGDAGEEAQGFVIELLLTLESAIDTLAETMKHYDLLSALSQTSYHDSVMGNKYAANRKSTGQINLSTSPINSGSCLGYYNNTRSNSLRLNLISERRGDRRRSNTLDIMDGRINHGGSLARTRSLSSLREGGMYDVQPTTDPVNLMATIFWIATSLLESDYEYEYLLALKLLNKLLIHLPLDKLESREKIEKVQNKLKWNNFPGLQQLFLKGFTSASTQEMTVHLLSKLITISRHALVDPSQLAGFPLNILCLLPHLIQHFDNPTQFCKETADRIAKVCAEEKSPTLANLAHMMSLYSTHSYSRDCSNWINVVCRYLHDSFSDATFNLVTYLAELLEKGLSSMQQSLLQIIYSLLSHIDLSTAPVKQFNLEIIKVIGKYVQSPYWKEALNILKLVVSRSASLVVPSDIPKSYGGDIGSPEISFTKIFNNVSKELPGKTLDFHFDISETPIIGNKYGDQHSAAGRNGKPKVIAVTRSTSSTSSGSNSNALVPVSWKRPQLSQRRTREKLMNVLSLCGPESGLPKNPSVVFSSNEDLEVGDQQTSLISTTEEVIQEEEVAVEDNTSEQQFGVFKDFDFLDVELEDAEELQGESMDNFNWGVRRRSLDSIDKGDTPSLQECQYSGSTPSLNLTNQEDTDESSEEEAALTASQILSRSQMLNSDSAIDETISDHAGLSLQSQDSTSSVGTEEVLQIRTETPSLEASLDNSSNQLPEEGCSAIRDEQVSTASEDTGSYLLQEQQDCLVCHEPLELEETPELAEPAAPESYCESICEEDVTLALKELDERCEEEEADFSGLSSQDEEEQDGFPEVQTSPPPSPFLSAILAAFQPVAYDDEEEAWRCHVNQMLSDTDGSCAVYTFHVFSRLFQTIQRKFVAITNDSVSFLGESLQRIGKKFKSSLEVMMLCSECPTVFVDAETLMSCGLLETLKFSVLELQEHLDTYNVKREAAEQWLADCKRTFGTDDGIHGTNTDAQQMEILAELELCRRLYKLHFQLLLLFQAYCKLISQVNTIKKEAEVINMSEELALLESCLKEAEAASDSGIEEIEIAEASQASTETAIHSLIEALRSKEFVSAVAQVKAFRSIWPHDIFGSSEDDPIQTLLHIYFRHQTLGQTGSFAVVGSNQDMSEASSKLMELNLEIRESLRMVQSYHLLGKIKPGVSLVSTGF", "length": 3021, "header": "tr|A0A8V0YQA9-1|A0A8V0YQA9_CHICK Isoform 1 of FRY like transcription coactivator OS=Gallus gallus OX=9031 GN=FRYL PE=4 SV=1 CANONICAL=A0A8V0YQA9-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YQA9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQA9/entry#A0A8V0YQA9-1", "sequence": { "sequence": "MSNITIDPDVKPGEYVIKSLFAEFAVQAEKKIEVVMAEPLEKLLSRSLQRGEDLQFDQLISSMSSVAEHCLPSLLRTLFDWYRRQNGTEDESYEYRPRSSTKSKGDDQQRERDYLLERRDLAVDFIFCLVLIEVLKQIPVHPVPDPLVHEVLNLAFKHFKHKEGYSGTNTGNVHIIADLYAEVTGVLAQSKFQAVRKKFVTELKELRQKEQSPHVVQSIISLIMGMKFFRVKMYPVEDFEASFQFMQECAQYFLEVKDKDIKHALAGLFVEILIPVAAAVKNEVNVPCLKNFVEMLYQTTFDLSSRKKHSLALYPLITCLLCVSQKQFFLNNWHVFLQNCLSHLKNKDPKMSRVALESLYRLLWVYVIRIKCESNTVTQSRLMSIVSALFPKGSRSVVPRDTPLNIFVKIIQFIAQERLDFAMKEIIFDLLSVGKSPKTFTINPERMNIGLRVFLVIADSLQQKDGEPPMPTTGVVLPSGNTLRVKKIFLNKTLTDEEAKVIGMSIYYPQVRKALDSILRHLDKEVGRPMCMTSVQMSNKEPEDMITGERKPKIDLFRTCIAAIPRLIPDGMSRTDLIELLARLTIHMDEELRALAFNTLQALMLDFPDWREDVLSGFVYFIVREVTDIHPTLLDNAVKMLVQLINQWKQAAQMHNKTQDSQRGVSSGAAHTLPLERTLYSNVFHVVEGFALVILCSTRPATRRLAVSVLREIRALFTLLEISKSDDELAIDVMDRQSASILESFIHLTGADQTTLLYCPSSVDLQTLADWSSSPISHQFDVVSPSHIWIFAHVTQGQDPWIISLSSFMKQENLPKHCPTAVSYAWMFAYTRLQMLSPQVDINSPINAKKVNTTTSSDSYIGLWRNYLILCCSAASSSSSSTSTGSVRCSPPETLASTPDSGYSIDSRIIGIPSPSSLFKHIVPMMRSESMEITESLVLGLGRTNPGAFRELIEELHPIIKEALERRPENMKRRRRRDILRVQLVRIFELLADAGVISHSASGGLDNETHSLNNTLLEYVDLTRQLLEAENEKDSDTLKDIRCHFSALVANIIQNVPVHQRRSVFPQQSLRHSLFMLFSHWAGPFSIMFTPLDRYSDRNMQINRHQYCALKAMSAVLCCGPVADNVGLSSDGYLYKWLDNILDSQDKKVHQLGCEAVTLLLELNPDQSNLMYWAVDRCYTGSKRVAAGCFKAIASVFQNRDYQCDTVTLLNLILFKAADSTRAIYEVAMQLLQILEPKMFRYAHKLEVQRTDGVLGQPSPLPHLYSVSYYQLSEELARTYPELTLAIFSEVSQRIQTAHPAGRQVMLHYLLPWMNNIELVDLKPLPTIRRQDEDEEDSLKDREIMVNSRRWLRGEGWGSPQATAMVLNNLMYMTAKYGDEVAWSEIENVWTTLADSWPKNLKIILHFLISICGVNSEPSLLPYVKKVIVYLGRDKTMQLLEELVSELQLTDPVSSGVTHMDNPPYYRITSSYKIPSVTSGTTSSSNTMVAPTDGNPDSKHIKDSIEENYAHLDIYSGLNSNLNRQHHRLESRYSSSSGGSYEEEKSDSMPLYSNWRLKVMEHNQGEPLPFPPTGGCWSPLVDYLPETTSPGMSLHRCNIAVILLTDLIVDHSVKVEWGGYLHLLLHAIFIGFDHCHPEVYEHCKRLLLHLLIVMGSGSNVQSVASVLLRNREFNESRMLTVKQTTHLDYTFTAGVHDFIPDYQPSPMTDSGLSSSSTSSSISLGNTSAAMSHMHTTILNEVDISVEQDEKVKTLIEFITSRKRGPLWNHEDVSAKNPSIKSAEQLTVFLKHVVSIFKQSSSGGFQLEHCLSEVALQTALSCSSRHYAGRSFQIFRALKQPLTASTLSDVLSRLVETVGDAGEEAQGFVIELLLTLESAIDTLAETMKHYDLLSALSQTSYHDSVMGNKYAANRKSTGQINLSTSPINSGSCLGYYNNTRSNSLRLNLISERRGDRRRSNTLDIMDGRINHGGSLARTRSLSSLREGGMYDVQPTTDPVNLMATIFWIATSLLESDYEYEYLLALKLLNKLLIHLPLDKLESREKIEKVQNKLKWNNFPGLQQLFLKGFTSASTQEMTVHLLSKLITISRHALVDPSQLAGFPLNILCLLPHLIQHFDNPTQFCKETADRIAKVCAEEKSPTLANLAHMMSLYSTHSYSRDCSNWINVVCRYLHDSFSDATFNLVTYLAELLEKGLSSMQQSLLQIIYSLLSHIDLSTAPVKQFNLEIIKVIGKYVQSPYWKEALNILKLVVSRSASLVVPSDIPKSYGGDIGSPEISFTKIFNNVSKELPGKTLDFHFDISETPIIGNKYGDQHSAAGRNGKPKVIAVTRSTSSTSSGSNSNALVPVSWKRPQLSQRRTREKLMNVLSLCGPESGLPKNPSVVFSSNEDLEVGDQQTSLISTTEEVIQEEEVAVEDNTSEQQFGVFKDFDFLDVELEDAEELQGESMDNFNWGVRRRSLDSIDKGDTPSLQECQYSGSTPSLNLTNQEDTDESSEEEAALTASQILSRSQMLNSDSAIDETISDHAGLSLQSQDSTSSVGTEEVLQIRTETPSLEASLDNSSNQLPEEGCSAIRDEQVSTASEDTGSYLLQEQQDCLVCHEPLELEETPELAEPAAPESYCESICEEDVTLALKELDERCEEEEADFSGLSSQDEEEQDGFPEVQTSPPPSPFLSAILAAFQPVAYDDEEEAWRCHVNQMLSDTDGSCAVYTFHVFSRLFQTIQRKFVAITNDSVSFLGESLQRIGKKFKSSLEVMMLCSECPTVFVDAETLMSCGLLETLKFSVLELQEHLDTYNVKREAAEQWLADCKRTFGTDDGIHGTNTDAQQMEILAELELCRRLYKLHFQLLLLFQAYCKLISQVNTIKKEAEVINMSEELALLESCLKEAEAASDSGIEEIEIAEASQASTETAIHSLIEALRSKEFVSAVAQVKAFRSIWPHDIFGSSEDDPIQTLLHIYFRHQTLGQTGSFAVVGSNQDMSEASSKLMELNLEIRESLRMVQSYHLLGKIKPGVSLVSTGF", "length": 3021, "header": "tr|A0A8V0YQA9-1|A0A8V0YQA9_CHICK Isoform 1 of FRY like transcription coactivator OS=Gallus gallus OX=9031 GN=FRYL PE=4 SV=1 CANONICAL=A0A8V0YQA9-1" }, "locus": { "chromosome": "4", "start_pos": 65957329, "end_pos": 65868045, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010040050.1", "url": "https://www.ensembl.org/id/ENSGALT00010040050.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023203.1", "url": "https://www.ensembl.org/id/ENSGALP00010023203.1" } ] } }, { "isoform_ac": "A0A8V0YWM8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQA9/entry#A0A8V0YWM8-1", "sequence": { "sequence": "MSNITIDPDVKPGEYVIKSLFAEFAVQAEKKIEVVMAEPLEKLLSRSLQRGEDLQFDQLISSMSSVAEHCLPSLLRTLFDWYRRQNGTEDESYEYRPRSSTKSKGDDQQRERDYLLERRDLAVDFIFCLVLIEVLKQIPVHPVPDPLVHEVLNLAFKHFKHKEGYSGTNTGNVHIIADLYAEVTGVLAQSKFQAVRKKFVTELKELRQKEQSPHVVQSIISLIMGMKFFRVKMYPVEDFEASFQFMQECAQYFLEVKDKDIKHALAGLFVEILIPVAAAVKNEVNVPCLKNFVEMLYQTTFDLSSRKKHSLALYPLITCLLCVSQKQFFLNNWHVFLQNCLSHLKMPSNNSIRKQIETLQNKDPKMSRVALESLYRLLWVYVIRIKCESNTVTQSRLMSIVSALFPKGSRSVVPRDTPLNIFVKIIQFIAQERLDFAMKEIIFDLLSVGKSPKTFTINPERMNIGLRVFLVIADSLQQKDGEPPMPTTGVVLPSGNTLRVKKIFLNKTLTDEEAKVIGMSIYYPQVRKALDSILRHLDKEVGRPMCMTSVQMSNKEPEDMITGERKPKIDLFRTCIAAIPRLIPDGMSRTDLIELLARLTIHMDEELRALAFNTLQALMLDFPDWREDVLSGFVYFIVREVTDIHPTLLDNAVKMLVQLINQWKQAAQMHNKTQDSQRGVSSGAAHTLPLERTLYSNVFHVVEGFALVILCSTRPATRRLAVSVLREIRALFTLLEISKSDDELAIDVMDRQSASILESFIHLTGADQTTLLYCPSSVDLQTLADWSSSPISHQFDVVSPSHIWIFAHVTQGQDPWIISLSSFMKQENLPKHCPTAVSYAWMFAYTRLQMLSPQVDINSPINAKKVNTTTSSDSYIGLWRNYLILCCSAASSSSSSTSTGSVRCSPPETLASTPDSGYSIDSRIIGIPSPSSLFKHIVPMMRSESMEITESLVLGLGRTNPGAFRELIEELHPIIKEALERRPENMKRRRRRDILRVQLVRIFELLADAGVISHSASGGLDNETHSLNNTLLEYVDLTRQLLEAENEKDSDTLKDIRCHFSALVANIIQNVPVHQRRSVFPQQSLRHSLFMLFSHWAGPFSIMFTPLDRYSDRNMQINRHQYCALKAMSAVLCCGPVADNVGLSSDGYLYKWLDNILDSQDKKVHQLGCEAVTLLLELNPDQSNLMYWAVDRCYTGSKRVAAGCFKAIASVFQNRDYQCDTVTLLNLILFKAADSTRAIYEVAMQLLQILEPKMFRYAHKLEVQRTDGVLGQPSPLPHLYSVSYYQLSEELARTYPELTLAIFSEVSQRIQTAHPAGRQVMLHYLLPWMNNIELVDLKPLPTIRRQDEDEEDSLKDREIMVNSRRWLRGEGWGSPQATAMVLNNLMYMTAKYGDEVAWSEIENVWTTLADSWPKNLKIILHFLISICGVNSEPSLLPYVKKVIVYLGRDKTMQLLEELVSELQLTDPVSSGVTHMDNPPYYRITSSYKIPSVTSGTTSSSNTMVAPTDGNPDSKHIKDSIEENYAHLDIYSGLNSNLNRQHHRLESRYSSSSGGSYEEEKSDSMPLYSNWRLKVMEHNQGEPLPFPPTGGCWSPLVDYLPETTSPGMSLHRCNIAVILLTDLIVDHSVKVEWGGYLHLLLHAIFIGFDHCHPEVYEHCKRLLLHLLIVMGSGSNVQSVASVLLRNREFNESRMLTVKQTTHLDYTFTAGVHDFIPDYQPSPMTDSGLSSSSTSSSISLGNTSAAMSHMHTTILNEVDISVEQDEKVKTLIEFITSRKRGPLWNHEDVSAKNPSIKSAEQLTVFLKHVVSIFKQSSSGGFQLEHCLSEVALQTALSCSSRHYAGRSFQIFRALKQPLTASTLSDVLSRLVETVGDAGEEAQGFVIELLLTLESAIDTLAETMKHYDLLSALSQTSYHDSVMGNKYAANRKSTGQINLSTSPINSGSCLGYYNNTRSNSLRLNLISERRGDRRRSNTLDIMDGRINHGGSLARTRSLSSLREGGMYDVQPTTDPVNLMATIFWIATSLLESDYEYEYLLALKLLNKLLIHLPLDKLESREKIEKVQNKLKWNNFPGLQQLFLKGFTSASTQEMTVHLLSKLITISRHALVDPSQLAGFPLNILCLLPHLIQHFDNPTQFCKETADRIAKVCAEEKSPTLANLAHMMSLYSTHSYSRDCSNWINVVCRYLHDSFSDATFNLVTYLAELLEKGLSSMQQSLLQIIYSLLSHIDLSTAPVKQFNLEIIKVIGKYVQSPYWKEALNILKLVVSRSASLVVPSDIPKSYGGDIGSPEISFTKIFNNVSKELPGKTLDFHFDISETPIIGNKYGDQHSAAGRNGKPKVIAVTRSTSSTSSGSNSNALVPVSWKRPQLSQRRTREKLMNVLSLCGPESGLPKNPSVVFSSNEDLEVGDQQTSLISTTEEVIQEEEVAVEDNTSEQQFGVFKDFDFLDVELEDAEGESMDNFNWGVRRRSLDSIDKGDTPSLQECQYSGSTPSLNLTNQEDTDESSEEEAALTASQILSRSQMLNSDSAIDETISDHAGLSLQSQDSTSSVGTEEVLQIRTETPSLEASLDNSSNQLPEEGCSAIRDEQVSTASEDTGSYLLQEQQDCLVCHEPLELEETPELAEPAAPESYCESICEEDVTLALKELDERCEEEEADFSGLSSQDEEEQDGFPEVQTSPPPSPFLSAILAAFQPVAYDDEEEAWRCHVNQMLSDTDGSCAVYTFHVFSRLFQTIQRKFVAITNDSVSFLGESLQRIGKKFKSSLEVMMLCSECPTVFVDAETLMSCGLLETLKFSVLELQEHLDTYNVKREAAEQWLADCKRTFGTDDGIHGTNTDAQQMEILAELELCRRLYKLHFQLLLLFQAYCKLISQVNTIKKEAEVINMSEELALLESCLKEAEAASDSGIEEIEIAEASQASTETAIHSLIEALRSKEFVSAVAQVKAFRSIWPHDIFGSSEDDPIQTLLHIYFRHQTLGQTGSFAVVGSNQDMSEASSKLMELNLEIRESLRMVQSYHLLGKIKPGVSLVSTGF", "length": 3033, "header": "tr|A0A8V0YWM8-1|A0A8V0YWM8_CHICK Computationally mapped isoform of FRY like transcription coactivator OS=Gallus gallus OX=9031 GN=FRYL PE=4 SV=1 CANONICAL=A0A8V0YQA9-1" }, "locus": { "chromosome": "4", "start_pos": 65957329, "end_pos": 65868045, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010040027.1", "url": "https://www.ensembl.org/id/ENSGALT00010040027.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023185.1", "url": "https://www.ensembl.org/id/ENSGALP00010023185.1" } ] } }, { "isoform_ac": "A0A8V0YX13-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQA9/entry#A0A8V0YX13-1", "sequence": { "sequence": "MLSLQDSLFFEISIKSLLKSWSGGGASTPPSRVNKRRVSPSVASTWEKRGIIMSNITIDPDVKPGEYVIKSLFAEFAVQAEKKIEVVMAEPLEKLLSRSLQRGEDLQFDQLISSMSSVAEHCLPSLLRTLFDWYRRQNGTEDESYEYRPRSSTKSKGDDQQRERDYLLERRDLAVDFIFCLVLIEVLKQIPVHPVPDPLVHEVLNLAFKHFKHKEGYSGTNTGNVHIIADLYAEVTGVLAQSKFQAVRKKFVTELKELRQKEQSPHVVQSIISLIMGMKFFRVKMYPVEDFEASFQFMQECAQYFLEVKDKDIKHALAGLFVEILIPVAAAVKNEVNVPCLKNFVEMLYQTTFDLSSRKKHSLALYPLITCLLCVSQKQFFLNNWHVFLQNCLSHLKNKDPKMSRVALESLYRLLWVYVIRIKCESNTVTQSRLMSIVSALFPKGSRSVVPRDTPLNIFVKIIQFIAQERLDFAMKEIIFDLLSVGKSPKTFTINPERMNIGLRVFLVIADSLQQKDGEPPMPTTGVVLPSGNTLRVKKIFLNKTLTDEEAKVIGMSIYYPQVRKALDSILRHLDKEVGRPMCMTSVQMSNKEPEDMITGERKPKIDLFRTCIAAIPRLIPDGMSRTDLIELLARLTIHMDEELRALAFNTLQALMLDFPDWREDVLSGFVYFIVREVTDIHPTLLDNAVKMLVQLINQWKQAAQMHNKTQDSQRGVSSGAAHTLPLERTLYSNVFHVVEGFALVILCSTRPATRRLAVSVLREIRALFTLLEISKSDDELAIDVMDRQSASILESFIHLTGADQTTLLYCPSSVDLQTLADWSSSPISHQFDVVSPSHIWIFAHVTQGQDPWIISLSSFMKQENLPKHCPTAVSYAWMFAYTRLQMLSPQVDINSPINAKKVNTTTSSDSYIGLWRNYLILCCSAASSSSSSTSTGSVRCSPPETLASTPDSGYSIDSRIIGIPSPSSLFKHIVPMMRSESMEITESLVLGLGRTNPGAFRELIEELHPIIKEALERRPENMKRRRRRDILRVQLVRIFELLADAGVISHSASGGLDNETHSLNNTLLEYVDLTRQLLEAENEKDSDTLKDIRCHFSALVANIIQNVPVHQRRSVFPQQSLRHSLFMLFSHWAGPFSIMFTPLDRYSDRNMQINRHQYCALKAMSAVLCCGPVADNVGLSSDGYLYKWLDNILDSQDKKVHQLGCEAVTLLLELNPDQSNLMYWAVDRCYTGSKRVAAGCFKAIASVFQNRDYQCDTVTLLNLILFKAADSTRAIYEVAMQLLQILEPKMFRYAHKLEVQRTDGVLGQPSPLPHLYSVSYYQLSEELARTYPELTLAIFSEVSQRIQTAHPAGRQVMLHYLLPWMNNIELVDLKPLPTIRRQDEDEEDSLKDREIMVNSRRWLRGEGWGSPQATAMVLNNLMYMTAKYGDEVAWSEIENVWTTLADSWPKNLKIILHFLISICGVNSEPSLLPYVKKVIVYLGRDKTMQLLEELVSELQLTDPVSSGVTHMDNPPYYRITSSYKIPSVTSGTTSSSNTMVAPTDGNPDSKHIKDSIEENYAHLDIYSGLNSNLNRQHHRLESRYSSSSGGSYEEEKSDSMPLYSNWRLKVMEHNQGEPLPFPPTGGCWSPLVDYLPETTSPGMSLHRCNIAVILLTDLIVDHSVKVEWGGYLHLLLHAIFIGFDHCHPEVYEHCKRLLLHLLIVMGSGSNVQSVASVLLRNREFNESRMLTVKQTTHLDYTFTAGVHDFIPDYQPSPMTDSGLSSSSTSSSISLGNTSAAMSHMHTTILNEVDISVEQDEKVKTLIEFITSRKRGPLWNHEDVSAKNPSIKSAEQLTVFLKHVVSIFKQSSSGGFQLEHCLSEVALQTALSCSSRHYAGRSFQIFRALKQPLTASTLSDVLSRLVETVGDAGEEAQGFVIELLLTLESAIDTLAETMKHYDLLSALSQTSYHDSVMGNKYAANRKSTGQINLSTSPINSGSCLGYYNNTRSNSLRLNLISERRGDRRRSNTLDIMDGRINHGGSLARTRSLSSLREGGMYDVQPTTDPVNLMATIFWIATSLLESDYEYEYLLALKLLNKLLIHLPLDKLESREKIEKVQNKLKWNNFPGLQQLFLKGFTSASTQEMTVHLLSKLITISRHALVDPSQLAGFPLNILCLLPHLIQHFDNPTQFCKETADRIAKVCAEEKSPTLANLAHMMSLYSTHSYSRDCSNWINVVCRYLHDSFSDATFNLVTYLAELLEKGLSSMQQSLLQIIYSLLSHIDLSTAPVKQFNLEIIKVIGKYVQSPYWKEALNILKLVVSRSASLVVPSDIPKSYGGDIGSPEISFTKIFNNVSKELPGKTLDFHFDISETPIIGNKYGDQHSAAGRNGKPKVIAVTRSTSSTSSGSNSNALVPVSWKRPQLSQRRTREKLMNVLSLCGPESGLPKNPSVVFSSNEDLEVGDQQTSLISTTEEVIQEEEVAVEDNTSEQQFGVFKDFDFLDVELEDAEGESMDNFNWGVRRRSLDSIDKGDTPSLQECQYSGSTPSLNLTNQEDTDESSEEEAALTASQILSRSQMLNSDSAIDETISDHAGLSLQSQDSTSSVGTEEVLQIRTETPSLEASLDNSSNQLPEEGCSAIRDEQVSTASEDTGSYLLQEQQDCLVCHEPLELEETPELAEPAAPESYCESICEEDVTLALKELDERCEEEEADFSGLSSQDEEEQDGFPEVQTSPPPSPFLSAILAAFQPVAYDDEEEAWRCHVNQMLSDTDGSCAVYTFHVFSRLFQTIQRKFVAITNDSVSFLGESLQRIGKKFKSSLEVMMLCSECPTVFVDAETLMSCGLLETLKFSVLELQEHLDTYNVKREAAEQWLADCKRTFGTDDGIHGTNTDAQELELCRRLYKLHFQLLLLFQAYCKLISQVNTIKKEAEVINMSEELALLESCLKEAEAASDSGIEEIEIAEASQASTETAIHSLIEALRSKEFVSAVAQVKAFRSIWPHDIFGSSEDDPIQTLLHIYFRHQTLGQTGSFAVVGSNQDMSEASSKLMELNLEIRESLRMVQSYHLLGKIKPGVSLVSTGF", "length": 3064, "header": "tr|A0A8V0YX13-1|A0A8V0YX13_CHICK Computationally mapped isoform of FRY like transcription coactivator OS=Gallus gallus OX=9031 GN=FRYL PE=4 SV=1 CANONICAL=A0A8V0YQA9-1" }, "locus": { "chromosome": "4", "start_pos": 65957329, "end_pos": 65842537, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010040018.1", "url": "https://www.ensembl.org/id/ENSGALT00010040018.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023177.1", "url": "https://www.ensembl.org/id/ENSGALP00010023177.1" } ] } }, { "isoform_ac": "A0A8V0Z3Q1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQA9/entry#A0A8V0Z3Q1-1", "sequence": { "sequence": 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"length": 3098, "header": "tr|A0A8V0Z3Q1-1|A0A8V0Z3Q1_CHICK Computationally mapped isoform of FRY like transcription coactivator OS=Gallus gallus OX=9031 GN=FRYL PE=4 SV=1 CANONICAL=A0A8V0YQA9-1" }, "locus": { "chromosome": "4", "start_pos": 65957329, "end_pos": 65828480, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010040057.1", "url": "https://www.ensembl.org/id/ENSGALT00010040057.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023209.1", "url": "https://www.ensembl.org/id/ENSGALP00010023209.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1492, "start_aa": "Thr", "end_pos": 1492, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1492", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 2329, "start_aa": "Thr", "end_pos": 2329, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr2329", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 2479, "start_aa": "Thr", "end_pos": 2479, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr2479", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 472, "start_aa": "Thr", "end_pos": 472, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr472", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "cell morphogenesis", "id": "GO:0000902", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000902", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQA9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQA9" } ], "pmid": "" }, { "name": "neuron projection development", "id": "GO:0031175", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031175", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQA9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQA9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cell cortex", "id": "GO:0005938", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005938", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQA9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQA9" } ], "pmid": "" }, { "name": "site of polarized growth", "id": "GO:0030427", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030427", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQA9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQA9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1007, "end_pos": 1009, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1013, "end_pos": 1015, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1674, "end_pos": 1676, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1725, "end_pos": 1727, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1920, "end_pos": 1922, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1936, "end_pos": 1938, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2284, "end_pos": 2286, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2417, "end_pos": 2419, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2483, "end_pos": 2485, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2560, "end_pos": 2562, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2732, "end_pos": 2734, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2873, "end_pos": 2875, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3, "end_pos": 5, "annotation": "n_glycosylation_sequon" }, { "start_pos": 491, "end_pos": 493, "annotation": "n_glycosylation_sequon" }, { "start_pos": 656, "end_pos": 658, "annotation": "n_glycosylation_sequon" }, { "start_pos": 852, "end_pos": 854, "annotation": "n_glycosylation_sequon" }, { "start_pos": 86, "end_pos": 88, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YQA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQA9" }, { "id": "PF14228", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14228" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Cell morphogenesis central region", "eco_id": "ECO_0000259", "start_pos": 1167, "end_pos": 1323, "start_aa": "Gln", "end_aa": "Lys", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0YQA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQA9" }, { "id": "PF14225", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14225" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Cell morphogenesis protein C-terminal", "eco_id": "ECO_0000259", "start_pos": 2002, "end_pos": 2254, "start_aa": "Ala", "end_aa": "Ser", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0YQA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQA9" }, { "id": "PF14222", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14222" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Cell morphogenesis protein N-terminal", "eco_id": "ECO_0000259", "start_pos": 117, "end_pos": 649, "start_aa": "Glu", "end_aa": "Lys", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0YQA9", "database": "UniProtKB", "url": 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"MQLAQLPAAADHYLAGRFAPALPLVAAGAGSARQNGAEPRSNLPPRRGGAGPGRTTALSCGGGERRNSCPGATRVTVPSAFRGGLAGSSSVLTERLGRGGASAAALPSSGSLLLPVPPIPGAVERPAGGGAGRAGGRCEEPGGKAAVPDGLFCPSVLSSVFPSRGLRAMSFRQRSPHGTARSSPQPPPRWSQGRKRGADGKRRKQSDGGVAVFEEAERGPSDSRADSFTTPEGPGPLSRCLDWAAAVEEDEMRTSVNKEIARYRRKLLVNEFSRERKSSSGSSDSKESTVTVELETDEVVLMRRQKQINYGKNTIAYDRYIKEVPRCHRIPGVHPRTPNKFKKYSRRSWDQQIKLWKVALHSWDPPTEEGCDLQEISPVDLGEMETESIGSNSTESQTSCRDNYDTCSGTPTKVRHIDYQAEGEFDLEACLSEPLKDLNSVS", "length": 442, "header": "tr|A0A8V0YQD1-1|A0A8V0YQD1_CHICK Isoform 1 of Stem-loop binding protein OS=Gallus gallus OX=9031 GN=SLBP PE=3 SV=1 CANONICAL=A0A8V0YQD1-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YQC7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQD1/entry#A0A8V0YQC7-1", "sequence": { "sequence": "MSFRQRSPHGTARSSPQPPPRWSQGRKRGADGKRRKQSDGGVAVFEEAERGPSDSRADSFTTPEGPGPLSRCLDWAAAVEEDEMRTSVNKEIARYRRKLLVNEFSRERKSSSGSSDSKESTVTVELETDEVVLMRRQKQINYGKNTIAYDRYIKEVPRCHRIPGVHPRTPNKFKKYSRRSWDQQIKLWKVALHSWDPPTEEGCDLQEISPVDLGEMETESIGSNSTESQTSCRDNYDTCSGTPTKVRHIDYQAEGEFDLEACLSEPLKDLNSIEGGVEKYFSSRVSFCFPFCLYCKDLPGCNADGRSILLIRMRTFVCCSYLSFSCLSF", "length": 329, "header": "tr|A0A8V0YQC7-1|A0A8V0YQD1_CHICK Computationally mapped isoform of Stem-loop binding protein OS=Gallus gallus OX=9031 GN=SLBP PE=3 SV=1 CANONICAL=A0A8V0YQD1-1" }, "locus": { "chromosome": "4", "start_pos": 83447107, "end_pos": 83440809, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010040069.1", "url": "https://www.ensembl.org/id/ENSGALT00010040069.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023218.1", "url": "https://www.ensembl.org/id/ENSGALP00010023218.1" } ] } }, { "isoform_ac": "A0A8V0YQD1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQD1/entry#A0A8V0YQD1-1", "sequence": { "sequence": "MQLAQLPAAADHYLAGRFAPALPLVAAGAGSARQNGAEPRSNLPPRRGGAGPGRTTALSCGGGERRNSCPGATRVTVPSAFRGGLAGSSSVLTERLGRGGASAAALPSSGSLLLPVPPIPGAVERPAGGGAGRAGGRCEEPGGKAAVPDGLFCPSVLSSVFPSRGLRAMSFRQRSPHGTARSSPQPPPRWSQGRKRGADGKRRKQSDGGVAVFEEAERGPSDSRADSFTTPEGPGPLSRCLDWAAAVEEDEMRTSVNKEIARYRRKLLVNEFSRERKSSSGSSDSKESTVTVELETDEVVLMRRQKQINYGKNTIAYDRYIKEVPRCHRIPGVHPRTPNKFKKYSRRSWDQQIKLWKVALHSWDPPTEEGCDLQEISPVDLGEMETESIGSNSTESQTSCRDNYDTCSGTPTKVRHIDYQAEGEFDLEACLSEPLKDLNSVS", "length": 442, "header": "tr|A0A8V0YQD1-1|A0A8V0YQD1_CHICK Isoform 1 of Stem-loop binding protein OS=Gallus gallus OX=9031 GN=SLBP PE=3 SV=1 CANONICAL=A0A8V0YQD1-1" }, "locus": { "chromosome": "4", "start_pos": 83446578, "end_pos": 83440305, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010040074.1", "url": "https://www.ensembl.org/id/ENSGALT00010040074.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023223.1", "url": "https://www.ensembl.org/id/ENSGALP00010023223.1" } ] } } ], 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"https://www.uniprot.org/uniprotkb/A0A8V0YQD1" } ], "pmid": "" }, { "name": "histone pre-mRNA stem-loop binding", "id": "GO:0071207", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071207", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQD1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQD1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQD1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQD1" } ], "pmid": "" }, { "name": "histone pre-mRNA 3'end processing complex", "id": "GO:0071204", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071204", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQD1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQD1" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQD1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQD1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "mRNA 3'-end processing by stem-loop binding and cleavage", "id": "GO:0006398", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006398", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQD1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQD1" } ], "pmid": "" }, { "name": "mRNA transport", "id": "GO:0051028", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051028", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQD1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQD1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 392, "end_pos": 394, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YQD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQD1" }, { "id": "PF15247", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15247" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Histone RNA hairpin-binding protein RNA-binding", "eco_id": "ECO_0000259", "start_pos": 297, "end_pos": 365, "start_aa": "Asp", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 392, "end_pos": 394 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { 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"n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YQF6-1", "uniprot_ac": "A0A8V0YQF6", "uniprot_id": "A0A8V0YQF6_CHICK", "mass": { "chemical_mass": 50535.0, "monoisotopic_mass": 50535.0 }, "refseq": { "ac": "XP_422217", "name": "tubulin epsilon and delta complex protein 1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_422217" }, "gene_names": [ { "name": "TEDC1", "type": "recommended", "evidence": [ { "id": "A0A8V0YQF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQF6" } ] }, { "name": "TEDC1", "type": "synonym", "evidence": [ { "id": "XP_422217", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_422217" } ] } ], "protein_names": [ { "name": "Tubulin epsilon and delta complex 1", "type": "synonym", "evidence": [ { "id": "A0A8V0YQF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQF6/entry#names_and_taxonomy" } ] }, { "name": "tubulin epsilon and delta complex protein 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_422217", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_422217" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052539.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_422217.3. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_422217", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_422217" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQF6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQF6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TEDC1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQF6", "locus": { "chromosome": "8", "start_pos": 3924903, "end_pos": 3987532, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013144", "url": "https://www.ensembl.org/id/ENSGALG00010013144" } ] } } ], "crossref": [ { "id": "A0A8V0YQF6", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YQF6", "database": "AlphaFoldDB", "categories": [] }, { "id": "424373", "url": "https://www.ncbi.nlm.nih.gov/gene/424373", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR027996", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027996", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043535", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043535", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "FIPPMKT", "url": "https://omabrowser.org/oma/group/FIPPMKT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YQF6", "url": "https://www.orthodb.org/?gene=A0A8V0YQF6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR35076", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR35076", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR35076:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR35076:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF14970", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14970", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_422217", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_422217", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YQF6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQF6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQF6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQF6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRRCRALPAAVGALCRALPPRARLAPDVLRRARFDRPQATLDFWRLLYALLKQIHGGEWTESDAIDTQIRFVKSALWYHGYGRPELYQLPSDGSAGSRELLLAFSWLLHRVNLLEWLLARNRVKTGDETSVCTCEDDLSHSQKDTTEMAPGLEDRVDVRYLQWLNGKLRFQWRSLHAQHQEQCKLLHKIHLFTSGSHTDQALGHFSVTETDLIRHPENYNQLLQHLELETMQLEAFLEWKQLEAVYWQWMETVLDNMAEEGSLRTVRDAPVETSRLQEGATCCPWAESMTVQIDRLSGEMTALHSQLQELVARRRSAWCQKVKTREEELQKEDFSTKLGKIEESVELKLLDLTNHGAPNKNKMHGSCRLVFRSKRSASKTGFGGSASKEPVPAVSATEVIRELRMREASLQRELKQLQDECKQRLDGIAERLDGVICISP", "length": 440, "header": "tr|A0A8V0YQF6-1|A0A8V0YQF6_CHICK Isoform 1 of Tubulin epsilon and delta complex 1 OS=Gallus gallus OX=9031 GN=TEDC1 PE=4 SV=1 CANONICAL=A0A8V0YQF6-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YQF6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQF6/entry#A0A8V0YQF6-1", "sequence": { "sequence": "MRRCRALPAAVGALCRALPPRARLAPDVLRRARFDRPQATLDFWRLLYALLKQIHGGEWTESDAIDTQIRFVKSALWYHGYGRPELYQLPSDGSAGSRELLLAFSWLLHRVNLLEWLLARNRVKTGDETSVCTCEDDLSHSQKDTTEMAPGLEDRVDVRYLQWLNGKLRFQWRSLHAQHQEQCKLLHKIHLFTSGSHTDQALGHFSVTETDLIRHPENYNQLLQHLELETMQLEAFLEWKQLEAVYWQWMETVLDNMAEEGSLRTVRDAPVETSRLQEGATCCPWAESMTVQIDRLSGEMTALHSQLQELVARRRSAWCQKVKTREEELQKEDFSTKLGKIEESVELKLLDLTNHGAPNKNKMHGSCRLVFRSKRSASKTGFGGSASKEPVPAVSATEVIRELRMREASLQRELKQLQDECKQRLDGIAERLDGVICISP", "length": 440, "header": "tr|A0A8V0YQF6-1|A0A8V0YQF6_CHICK Isoform 1 of Tubulin epsilon and delta complex 1 OS=Gallus gallus OX=9031 GN=TEDC1 PE=4 SV=1 CANONICAL=A0A8V0YQF6-1" }, "locus": { "chromosome": "8", "start_pos": 3987490, "end_pos": 3925783, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031506.1", "url": "https://www.ensembl.org/id/ENSGALT00010031506.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018401.1", "url": "https://www.ensembl.org/id/ENSGALP00010018401.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A8I5ZZB2-1", "protein_name": "Tubulin epsilon and delta complex 1", "gene_name": "Tedc1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGRRRSRVEGAARALPEAVAALSRSLPAGPSPEIFRRAKFDRPEAAPVLWQLLLRVLSPLAANNTWTDLAPEAQARVVKSALGSRGYPRSVLLQFPDGSSQGSRELLLALSWLLAQGPLLEQLLAQTRVQVGDQLPQCEALTSPGPLACLVATKSPVDLRLVEWLMGKLRFRWRCLILSQREQCTLLSKIHLYTQGCHSQQSLGHLSVAETEMLRDPESSQQLLHALESENARLEAALEWRRCELVFWQWMDTVLDACSPETPAVTSQPTALPMISEGGLGELESVRQELLALQEELREVAEPRRAAWESRVGGLGQGPEWSNSRKALREVVERELADLQGSWKLCSTPAQPQRPHRLVRSKDGAPRRQGLQAAEVIRTLSAKEDCLKKALHQLQCQCQQELARLAGTLPGLIWVLPPGH", "length": 420 }, "evidence": [ { "id": "A0A8V0YQF6", "url": "https://omabrowser.org/oma/group/A0A8V0YQF6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q3UK37-1", "protein_name": "Tubulin epsilon and delta complex protein 1", "gene_name": "Tedc1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRRRRSRVEGAARALPEAVAALSRCLPAGPSPEIFRRAKFDRPEAAPVLWQLLLRVLSPLAANNTWTDLAPEAQACVVKSALGSQGYPRSVLLQFPDGSSQGSRELLLALSWLLARGPLLEQLLAQTRVQLGDQLPQWEAPTSPGPPAPFVEPKSPVDLRLVEWLMGRLRFRWRCLISSQQEQCILLSKIHLYTQGCHSQQSLGHLSVAETEMLRDPESGQQLLQALESENIRLEAALEWRRRELVFWQWMDTVLDTCSPETPAVTSQPTFLPEISEGGLGELESVKQELQALQEELREVSEPRRAAWEARVGGLGQGPEWSNSRKALQEAVQQELAALQGSWEQSSTPGQPQRPHRLVRSKDGAPRPQGLQAAEVIRTLSAKEACLKKALHQLQRQCQQELARLAGALPGLIWILPPEH", "length": 420 }, "evidence": [ { "id": "A0A8V0YQF6", "url": "https://omabrowser.org/oma/group/A0A8V0YQF6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q86SX3-1", "protein_name": "Tubulin epsilon and delta complex protein 1", "gene_name": "TEDC1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGRRRQRVDPAAGARAGALPEAIAALSRSLPSGPSPEIFRRAKFDRPEATSALWQLLFRVLSPLPAGNALASLALEVQARLVKSALCSQGYPRLALAQLPEDGSQGSRELLLALSWLLARGPVPEQMLAQARVPLGDEMTVCQCEALASPGPPAPHMEAEGPVDVRHVQWLMGKLRFRWRQLVSSQQEQCALLSKIHLYTRGCHSDQSLSHLSVTEAEMLRDPEGGQQVSGAGAAQNLDLAYPKCLHSFCTPGMGPRTFWNDLWLVCEQPGLLPGDWAAPLDPGGASACSLLSPFRALLRTLERENQRLEAVLAWRRSELVFWRWMDTVLGTCAPEVPAAASQPTFLPWVPERGGGELDLVVRELQALEEELREAAERRRAAWEAKAGGCGRGPEWSAARRASREAVEKELGALQQCWERDGGPAQPHGPHRLVRREDGAAGDRDLRAAVVIRTLRSQEACLEAVLRRLQGQCRQELARLVGARPGLIWIPPPGR", "length": 495 }, "evidence": [ { "id": "A0A8V0YQF6", "url": "https://omabrowser.org/oma/group/A0A8V0YQF6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "positive regulation of smoothened signaling pathway", "id": "GO:0045880", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045880", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQF6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQF6" } ], "pmid": "" }, { "name": "microtubule cytoskeleton organization", "id": "GO:0000226", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000226", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQF6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQF6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQF6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQF6" } ], "pmid": "" }, { "name": "cilium", "id": "GO:0005929", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005929", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQF6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQF6" } ], "pmid": "" }, { "name": "centriole", "id": "GO:0005814", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005814", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQF6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQF6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YQF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQF6" }, { "id": "PF14970", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14970" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Tubulin epsilon and delta complex protein 1", "eco_id": "ECO_0000259", "start_pos": 80, "end_pos": 255, "start_aa": "Gly", "end_aa": "Asp", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YQG7-1", "uniprot_ac": "A0A8V0YQG7", "uniprot_id": "A0A8V0YQG7_CHICK", "mass": { "chemical_mass": 40353.0, "monoisotopic_mass": 40353.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "NALCN channel auxiliary factor 1", "type": "synonym", "evidence": [ { "id": "A0A8V0YQG7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQG7/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQG7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQG7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQG7", "locus": {} } ], "crossref": [ { "id": "A0A8V0YQG7", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YQG7", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR055288", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055288", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR15819", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15819", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15819:SF9", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15819:SF9", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YQG7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQG7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQG7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQG7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTRGAWMCSRQYDDGLKIWFASRENEKPFADSERAQKWRLSLASLLFFTVLLSDHLWFCAEAKFTGTGEKEQPPPDKPEPAEPELPPGMGEPSPPAPRLLTPPEPSLPPSPGNGGGGGGGSEPRHGEAAFLGNSTAAPPETCPPPGRSSGRCFSVGDAEAVCRRRGDPGRPRGAGQSPAPGWELTDFYLSFCNSYTLWELFAGLSNPDTLNCSLDVVLRGGGSCSQCVQAYQRYDQHAQEKYEEFEVMLQKYLQSDEYSVKSCPEDCKVGAPAVFPVPRRYCGRKITLLIRAMRKGCNFVFCRLAWRWPGSGRPLSVVLQGSARSWRLSEPSRAAGSRSVPRAPRVGAAGLFWFTLVADEAECLAGPVLC", "length": 370, "header": "tr|A0A8V0YQG7-1|A0A8V0YQG7_CHICK Isoform 1 of NALCN channel auxiliary factor 1 OS=Gallus gallus OX=9031 GN= PE=3 SV=1 CANONICAL=A0A8V0YQG7-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YQG7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQG7/entry#A0A8V0YQG7-1", "sequence": { "sequence": "MTRGAWMCSRQYDDGLKIWFASRENEKPFADSERAQKWRLSLASLLFFTVLLSDHLWFCAEAKFTGTGEKEQPPPDKPEPAEPELPPGMGEPSPPAPRLLTPPEPSLPPSPGNGGGGGGGSEPRHGEAAFLGNSTAAPPETCPPPGRSSGRCFSVGDAEAVCRRRGDPGRPRGAGQSPAPGWELTDFYLSFCNSYTLWELFAGLSNPDTLNCSLDVVLRGGGSCSQCVQAYQRYDQHAQEKYEEFEVMLQKYLQSDEYSVKSCPEDCKVGAPAVFPVPRRYCGRKITLLIRAMRKGCNFVFCRLAWRWPGSGRPLSVVLQGSARSWRLSEPSRAAGSRSVPRAPRVGAAGLFWFTLVADEAECLAGPVLC", "length": 370, "header": "tr|A0A8V0YQG7-1|A0A8V0YQG7_CHICK Isoform 1 of NALCN channel auxiliary factor 1 OS=Gallus gallus OX=9031 GN= PE=3 SV=1 CANONICAL=A0A8V0YQG7-1" }, "locus": { "chromosome": "1", "start_pos": 140402596, "end_pos": 140399649, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010036037.1", "url": "https://www.ensembl.org/id/ENSGALT00010036037.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020922.1", "url": "https://www.ensembl.org/id/ENSGALP00010020922.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQG7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQG7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "calcium ion import across plasma membrane", "id": "GO:0098703", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098703", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQG7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQG7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 133, "end_pos": 135, "annotation": "n_glycosylation_sequon" }, { "start_pos": 211, "end_pos": 213, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], 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The reference sequence was derived from JAENSK010000240.1. 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[ "Enzyme and Pathway" ] }, { "id": "34991", "url": "https://www.rhea-db.org/rhea/34991", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "70827", "url": "https://www.rhea-db.org/rhea/70827", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "70935", "url": "https://www.rhea-db.org/rhea/70935", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "71063", "url": "https://www.rhea-db.org/rhea/71063", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "71199", "url": "https://www.rhea-db.org/rhea/71199", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "72799", "url": "https://www.rhea-db.org/rhea/72799", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "72803", "url": "https://www.rhea-db.org/rhea/72803", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "72807", "url": "https://www.rhea-db.org/rhea/72807", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YQJ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQJ0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQJ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQJ0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YWW7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YWW7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YWW7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YWW7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQGQDSPLQIGRGCTNPDEETRIPGILKNWKSNLKNKSNVAWTGAAGVLVGHPFDTVKVRLQVQNVEKPLYRGTFHCFQSIIKQESAFGLYKGIGSPMMGLTFINAVVFGVQGNTLRALGKDTPLNQFLAGSAAGAIQCIICCPMELAKTRMQLQGTGEYKQKTKNYKNSLDCLIKIYRKEGLRGINRGMVSTVIRETPSFGFYFLTYDCMTRYLGCEAEDSYVIPKLLFSGGMSGIVSWLSTYPVDVIKSRLQADGVGGVTQYKGILDCVRKSYQEEGWKVFTRGLTSTLLRAFPVNAATFATVTVFLMYMRSENDLRECDPGPVIQQPSSL", "length": 333, "header": "tr|A0A8V0YQJ0-1|A0A8V0YQJ0_CHICK Isoform 1 of Mitochondrial basic amino acids transporter OS=Gallus gallus OX=9031 GN=SLC25A29 PE=1 SV=1 CANONICAL=A0A8V0YQJ0-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YQJ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQJ0/entry#A0A8V0YQJ0-1", "sequence": { "sequence": "MQGQDSPLQIGRGCTNPDEETRIPGILKNWKSNLKNKSNVAWTGAAGVLVGHPFDTVKVRLQVQNVEKPLYRGTFHCFQSIIKQESAFGLYKGIGSPMMGLTFINAVVFGVQGNTLRALGKDTPLNQFLAGSAAGAIQCIICCPMELAKTRMQLQGTGEYKQKTKNYKNSLDCLIKIYRKEGLRGINRGMVSTVIRETPSFGFYFLTYDCMTRYLGCEAEDSYVIPKLLFSGGMSGIVSWLSTYPVDVIKSRLQADGVGGVTQYKGILDCVRKSYQEEGWKVFTRGLTSTLLRAFPVNAATFATVTVFLMYMRSENDLRECDPGPVIQQPSSL", "length": 333, "header": "tr|A0A8V0YQJ0-1|A0A8V0YQJ0_CHICK Isoform 1 of Mitochondrial basic amino acids transporter OS=Gallus gallus OX=9031 GN=SLC25A29 PE=1 SV=1 CANONICAL=A0A8V0YQJ0-1" }, "locus": { "chromosome": "5", "start_pos": 48054552, "end_pos": 48046282, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010040154.1", "url": "https://www.ensembl.org/id/ENSGALT00010040154.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023280.1", "url": "https://www.ensembl.org/id/ENSGALP00010023280.1" } ] } }, { "isoform_ac": "A0A8V0YWW7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQJ0/entry#A0A8V0YWW7-1", "sequence": { "sequence": "MSERQKGHLLHSFRRLSTLVLKTLFFPSFFHQAFGLYKGIGSPMMGLTFINAVVFGVQGNTLRALGKDTPLNQFLAGSAAGAIQCIICCPMELAKTRMQLQGTGEYKQKTKNYKNSLDCLIKIYRKEGLRGINRGMVSTVIRETPSFGFYFLTYDCMTRYLGCEAEDSYVIPKLLFSGGMSGIVSWLSTYPVDVIKSRLQADGVGGVTQYKGILDCVRKSYQEEGWKVFTRGLTSTLLRAFPVNAATFATVTVFLMYMRSENDLRECDPGPVIQQPSSL", "length": 279, "header": "tr|A0A8V0YWW7-1|A0A8V0YWW7_CHICK Computationally mapped isoform of Mitochondrial basic amino acids transporter OS=Gallus gallus OX=9031 GN=SLC25A29 PE=1 SV=1 CANONICAL=A0A8V0YQJ0-1" }, "locus": { "chromosome": "5", "start_pos": 48047118, "end_pos": 48046282, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010040151.1", "url": "https://www.ensembl.org/id/ENSGALT00010040151.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023277.1", "url": "https://www.ensembl.org/id/ENSGALP00010023277.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-352230", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-352230", "resource": "Reactome", "description": "Amino acid transport across the plasma membrane" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQJ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQJ0" } ], "pmid": "" }, { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQJ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQJ0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "high-affinity L-arginine transmembrane transporter activity", "id": "GO:0005289", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005289", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQJ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQJ0" } ], "pmid": "" }, { "name": "high-affinity lysine transmembrane transporter activity", "id": "GO:0005292", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005292", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQJ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQJ0" } ], "pmid": "" }, { "name": "O-acyl-L-carnitine transmembrane transporter activity", "id": "GO:0015227", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015227", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQJ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQJ0" } ], "pmid": "" }, { "name": "basic amino acid transmembrane transporter activity", "id": "GO:0015174", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015174", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQJ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQJ0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "L-histidine transmembrane transport", "id": "GO:0089709", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0089709", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQJ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQJ0" } ], "pmid": "" }, { "name": "mitochondrial L-ornithine transmembrane transport", "id": "GO:1990575", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990575", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQJ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQJ0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 36, "end_pos": 38, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "32143", "name": "", "equation": "L-arginine(in) = L-arginine(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "32143", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/32143" } ] }, { "id": "34991", "name": "", "equation": "L-ornithine(in) + L-arginine(out) = L-ornithine(out) + L-arginine(in)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "34991", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/34991" } ] }, { "id": "70827", "name": "", "equation": "L-lysine(out) + L-arginine(in) = L-lysine(in) + L-arginine(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "70827", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/70827" } ] }, { "id": "70935", "name": "", "equation": "L-lysine(in) = L-lysine(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "70935", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/70935" } ] }, { "id": "71063", "name": "", "equation": "L-histidine(out) + L-arginine(in) = L-histidine(in) + L-arginine(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "71063", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/71063" } ] }, { "id": "71199", "name": "", "equation": "L-ornithine(in) = L-ornithine(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "71199", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/71199" } ] }, { "id": "72799", "name": "", "equation": "L-homoarginine(in) + L-arginine(out) = L-homoarginine(out) + L-arginine(in)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "72799", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/72799" } ] }, { "id": "72803", "name": "", "equation": "N(omega)-methyl-L-arginine(in) + L-arginine(out) = N(omega)-methyl-L-arginine(out) + L-arginine(in)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "72803", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/72803" } ] }, { "id": "72807", "name": "", "equation": "L-histidine(out) = L-histidine(in)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "72807", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/72807" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 36, "end_pos": 38 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": 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} ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YQJ2-1", "uniprot_ac": "A0A8V0YQJ2", "uniprot_id": "A0A8V0YQJ2_CHICK", "mass": { "chemical_mass": 12590.0, "monoisotopic_mass": 12590.0 }, "refseq": { "ac": "XP_025008961", "name": "uncharacterized protein KIAA0040 homolog", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025008961" }, "gene_names": [ { "name": "KIAA0040", "type": "recommended", "evidence": [ { "id": "A0A8V0YQJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQJ2" } ] }, { "name": "KIAA0040", "type": "synonym", "evidence": [ { "id": "XP_025008961", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025008961" } ] } ], "protein_names": [ { "name": "KIAA0040", "type": "synonym", "evidence": [ { "id": "A0A8V0YQJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQJ2/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein KIAA0040 homolog", "type": "synonym", "evidence": [ { "id": "XP_025008961", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025008961" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052539.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_025008961", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025008961" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQJ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQJ2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "KIAA0040", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQJ2", "locus": { "chromosome": "8", "start_pos": 7069948, "end_pos": 7069619, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010014347", "url": "https://www.ensembl.org/id/ENSGALG00010014347" } ] } } ], "crossref": [ { "id": "A0A8V0YQJ2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YQJ2", "database": "AlphaFoldDB", "categories": [] }, { "id": "424434", "url": "https://www.ncbi.nlm.nih.gov/gene/424434", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR039964", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039964", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:424434", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424434", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "GIFNTIC", "url": "https://omabrowser.org/oma/group/GIFNTIC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YQJ2", "url": "https://www.orthodb.org/?gene=A0A8V0YQJ2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR40382", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR40382", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR40382:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR40382:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "XP_025008961", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025008961", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YQJ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQJ2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQJ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQJ2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEQKISSFFNSILELVRTKHKEGVFNTVCLAVLLGLPFVVLIASIFICCHCCISHWRRQSRKRDSPSSNGQLQAERNKKKKKKKKDEEDLWISAQPKLLLLDKRPSLPI", "length": 109, "header": "tr|A0A8V0YQJ2-1|A0A8V0YQJ2_CHICK Isoform 1 of KIAA0040 OS=Gallus gallus OX=9031 GN=KIAA0040 PE=4 SV=1 CANONICAL=A0A8V0YQJ2-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YQJ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQJ2/entry#A0A8V0YQJ2-1", "sequence": { "sequence": "MEQKISSFFNSILELVRTKHKEGVFNTVCLAVLLGLPFVVLIASIFICCHCCISHWRRQSRKRDSPSSNGQLQAERNKKKKKKKKDEEDLWISAQPKLLLLDKRPSLPI", "length": 109, "header": "tr|A0A8V0YQJ2-1|A0A8V0YQJ2_CHICK Isoform 1 of KIAA0040 OS=Gallus gallus OX=9031 GN=KIAA0040 PE=4 SV=1 CANONICAL=A0A8V0YQJ2-1" }, "locus": { "chromosome": "8", "start_pos": 7069945, "end_pos": 7069619, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034547.1", "url": "https://www.ensembl.org/id/ENSGALT00010034547.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020288.1", "url": "https://www.ensembl.org/id/ENSGALP00010020288.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:424434", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424434", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3Q1ML37-1", "protein_name": "KIAA0040", "gene_name": "KIAA0040", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MEKISMFFSAVWDVISTKHQEGLFNSICLGILLGLPLLVIITFLFICCHCCWNRPGDNGRQPEQNKGKKKKKKKKQAEEDLWISAQPKLLQMEKRPSLPV", "length": 100 }, "evidence": [ { "id": "A0A8V0YQJ2", "url": "https://omabrowser.org/oma/group/A0A8V0YQJ2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A8D1U0T1-1", "protein_name": "KIAA0040", "gene_name": "KIAA0040", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEKISAFFSAIWDIISSKHQEGLFNSICLGILLGLPLLVIITFLFICCHCCWNRPSKSGQQPEQNKGKKKKKKKAEEDLWISAQPKLLQLEKRPSLPV", "length": 98 }, "evidence": [ { "id": "A0A8V0YQJ2", "url": "https://omabrowser.org/oma/group/A0A8V0YQJ2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8I5Y713-1", "protein_name": "KIAA0040 ortholog", "gene_name": "Kiaa0040", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MERNSTFFDSIWETILTRHERGVFNTVCLAVLLGLPLVVLLTLFFICCHCCCSRPPKSNQQAEQNKKKKKKKKKKKKDEDLWISAQPKLLQMEKRPSLPV", "length": 100 }, "evidence": [ { "id": "A0A8V0YQJ2", "url": "https://omabrowser.org/oma/group/A0A8V0YQJ2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E9Q2T4-1", "protein_name": "RIKEN cDNA 4930523C07 gene", "gene_name": "4930523C07Rik", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MERNSSFFNSVWETIRIRHERGVFNTVCLAVLLGLPLVVVLTLFFICCHCCCSRPPKSNQQPDQNKKKKKKKKKKKDEDLWISAQPKLLQMEKRPSLLV", "length": 99 }, "evidence": [ { "id": "A0A8V0YQJ2", "url": "https://omabrowser.org/oma/group/A0A8V0YQJ2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "G3GZM1-1", "protein_name": "Uncharacterized protein KIAA0040 homolog", "gene_name": "Kiaa0040", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MERNSSFFNSIWETIRTRHERGIFNTVCLAVLLGLPLVVVLTLLFICCHCCCSRPPKSGQQPDQNKKKKKKKKKKKDEDLWISAQPKLLQMEKRPSLPL", "length": 99 }, "evidence": [ { "id": "A0A8V0YQJ2", "url": "https://omabrowser.org/oma/group/A0A8V0YQJ2/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q15053-1", "protein_name": "Uncharacterized protein KIAA0040", "gene_name": "KIAA0040", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MERISAFFSSIWDTILTKHQEGIYNTICLGVLLGLPLLVIITLLFICCHCCWSPPGKRGQQPEKNKKKKKKKKKKDEEDLWISAQPKLLQMEKRPSLPV", "length": 99 }, "evidence": [ { "id": "A0A8V0YQJ2", "url": "https://omabrowser.org/oma/group/A0A8V0YQJ2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YQJ5-1", "uniprot_ac": "A0A8V0YQJ5", "uniprot_id": "A0A8V0YQJ5_CHICK", "mass": { "chemical_mass": 344588.0, "monoisotopic_mass": 344588.0 }, "refseq": { "ac": "XP_004939564", "name": "TPR and ankyrin repeat-containing protein 1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004939564" }, "gene_names": [ { "name": "TRANK1", "type": "recommended", "evidence": [ { "id": "A0A8V0YQJ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQJ5" } ] }, { "name": "TRANK1", "type": "synonym", "evidence": [ { "id": "XP_004939564", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004939564" } ] } ], "protein_names": [ { "name": "TPR and ankyrin repeat-containing protein 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_004939564", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004939564" } ] }, { "name": "Tetratricopeptide repeat and ankyrin repeat containing 1", "type": "synonym", "evidence": [ { "id": "A0A8V0YQJ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQJ5/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052533.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_004939564.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004939564", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004939564" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQJ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQJ5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TRANK1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQJ5", "locus": { "chromosome": "2", "start_pos": 45870538, "end_pos": 45911909, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010016655", "url": "https://www.ensembl.org/id/ENSGALG00010016655" } ] } } ], "crossref": [ { "id": "420728", "url": "https://www.ncbi.nlm.nih.gov/gene/420728", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011990", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011990", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014016", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014016", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036770", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036770", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039904", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039904", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:420728", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420728", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "SQCEVEP", "url": "https://omabrowser.org/oma/group/SQCEVEP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YQJ5", "url": "https://www.orthodb.org/?gene=A0A8V0YQJ5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YWX2", "url": "https://www.orthodb.org/?gene=A0A8V0YWX2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YYU0", "url": "https://www.orthodb.org/?gene=A0A8V0YYU0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21529", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21529", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21529:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21529:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00580", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00580", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_004939564", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004939564", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YQJ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQJ5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQJ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQJ5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YWX2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YWX2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YWX2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YWX2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YYU0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYU0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YYU0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYU0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVEMICSPDFILDEPDQEHDPERVRCTPNMWRTFTKTAPESMDAMEYAQFMKQDGNQDFKNGNYALAIRKYDQALYMLVQLRQWGLCSGDIAVLYCNKSTCLYNLGKWREAMLSAFESLRWDPQYVKAYYRAGHSLIMLSNAYNAVCMFHRGLTLLNASVDQAQVADFIAGIFTSVNDERVLPPTFYPAYDYIFSARFDALIWQSVMEKLAQKGKWQSFLLLLSKKKDLPTNLRVNQLPLKNLFETFELYGCDETMQNVAELVKWLISIGAKVESIGVYPLHAVIRLCIKAKKNHIFRWLLSQRPDLKDRINQQDRDGCTLLHIVASSSDYSRKRSQTEDVLMLLNFGVDPTIPDARSRNVIDILKKNKNFDAVKAVSNHIEKHTSSSVELEDEDRRRAVVDSFLDALEQFVKFCSFENGLHHKNILKEDVFQRFLKLLSSVKEIPDGVVCNISQACANSIVKLLLKKQMWHEVLLLLTGKANGENASDGGLLKACSLSDVDIGSIIQQCDRLDERVHLIRCLVERGALPDGTGAKSEIPLQICLKKNYIELVYLLLTKGADPRNISFAKGDTPLHAAVHICLDKRDGTGINILNYLLDLFASRPSDFPYLNPNVQDDNGNTVMHVIFQRGFSKQAKRIMDSLAKFDVNFNIKNKLGRDVRHRIKKNDPLLLAWNTAVSEKKKYRQDIAGQLVKTPKPTPASDVSQPKNAGRSSSGSLLKVPSGNTARNDVKTQSSVKTKNDQLSKQEMEKIKNPLTMQESLVQEIAALIQQLKWGDALRKDNSVVQKQSSGQTNLEEGKSASLQLSGSAVYSEGRGDDREKKKGVQEFSVGLSNGEKEAPDEEMILDIEAYVQEFDNMTWEIECTPEALKTLGSKDVPHYLKTKTIMTIKRLGNGEWTKGLQKPLKHLKADIQLYEAKLGKGARMLWELAIDFSPRCSESAEKIMETEQTKSLPEKSGRVYTEMIRIWAIVLDHCKLNRVLDNICLSYNRGLSCILRKKLKGINEGHQNYNVTMHKRVPRCYVEDLEREKSKEHTIPEYFPPASAAEMEYNIMKFHSFSTNMALNIINDVHSAVEYPFRVGELEYAVIDLNPKPMEPIILIGRSGTGKTTCCLYRLWKKFYSYWEKSTMANSPLLERQTWRQRQCSDVEKARLENEECEEKQDNDDSSEEQVSEEQDQDSEDEEVATGTSDAETSPCDDHEEGQKCNSEEPNTLEHLHQIFVTKNPVLCQEVQKNFIELSKSSKVTSHFKPLEPNVHRLQDVKDENFPLFITSKQLLLLLDASLPDPFFPRNEDGSLKRTIVGWSPQEELVIPNWQDEDEECNAEAEDGDEERTADGYSRESDPRTFVTYDLFANEIWPKMIKGKSLYNPALVWKEIKSFLKGSFEALSCFGGKLTEEQYKKLGRKRSPNFTEDRSEIYHLFCLYQQIRSQRGYFDEEDLLYNLSQRLSQLGELPWSIHEFYGDEIQDFTQAELALLMKCINDPNSMFLTGDTAQSIMKGVAFRFSDLRSLFHYASKNTVDKKQRVRKPKRIYQLYQNYRSHSGILSLASGVVDLLQYYFPESFDRLPKDCGLFDGPKPTVLESCSFSDLAILLRGNKRKTQPIEFGAHQVVLVANETAKEKIPEELSLALVLTVYEAKGLEFDDVLLYNFFTDSEASKEWKIISSYTPDSDVQVGSKLLIEMPLEDATAMQKRPTSFNAEMYKMLNGELKQLYTAITRARVNLWIFDENSDKRAPAFKYFIKRGFVQVVKTDENKDLDDSMFAKTSSPEEWIAQGDYYAKHQFWEVAAKCYQKGGAAEKSKLALAHDAVLKVHSKKSSPREKQMEYMTLAKTYLECGESKLSLKCLFQSKEFRLCAELCKKLGKMKDAAVYYQKNQCYKEASECYEQIEEFDLAIKMYCQEELYEEAAKAVERYEEMLNARGQMVSKLSCTANQLYLEAAAKYLSVNRIEEMMQVLSKLDIEDQLEFLKSRGCLHQTADLLKREGRQEEAAKLMKQHGYALEAANLTAIKEFRASCLLAAVRAGTTHCSESNLVDREIMLREALELCEQTNQKSGIAEALFLQGAPKRDFTKLSNAYFQFLSVNHSAGAVEVLFVLSRCSAPSQEILCKATHGLMALLDLVKSLKKATTNVEKDMVKSCFAYFGIIPTGDSCCQVSQNEAEPILKFLLDKASLKERKTKGNFSVSTEAVKSALKQHLLSRLCSITHELLNKHYPDICMKFIVGLNCEDSTCGDFHKPLMRHEARMVFQCKMNLAAINGLLLEATHTFPKELLSHCKSFDGLLTSDKYVSCKALLETFFPNHFHLRILSENPKACKEILGFSNITSKPCRALLNEYISFKFKDEDARARRESSDLWLSAMKVFLLSSGYPEEFEKLLFKEEDDYNRELNLALSKAKSSPKSKSHGGKIKGIDGRHGMLQPDKKTENAGRTHLCFIRLLQSSFEQFYVYKNPESCKRLFFRFMNVLVKKCTRYLIPSIGNTVMLLEFQYIICCAVLMRLNKNVTLCLPKSYIALVHYWDFLFRNKGRSKEFTETFSIIQEYRPKDILVAEQNFRFHLCYLAKILCGVHENFSVLLDAFEDPDCVTSGEAERTVVLSLVMILNADQVQNSMCKYLLSQLFPEIKGMLKAMRKDSPSKVPVRLLKVVEQVAAASGVREVAASLQELLIERDEEYLFDCRWRWDSVYTQGYAPIRGILYENVNFDRFIASLDKTEYADEIEKELESDQCLEDQKDPLEVIALNKQQKQEQKASALRHLYRVFHFVFVCMRWKRKACCKAEPVAVEGEEFLSDIFKKADIDQTQCDLCGVRFIQSSENYFSQTESVEADTSEAVTPTEEKMQVEGNAIIAASEAYMEHRNTDKHRNNNAAYKNYADFFRRWIDPKIRDGLDVVEAITERTYTQDHLAYKEGSNLCQRKIKENIKKISDAVEEIYERKAWAEAEEIITEHANKLFAVTDEAYKWLKKMDLQRIKEEDFVHDRDLENEVEDESMAFEELAYKKPSRKKGRYGKW", "length": 3008, "header": "tr|A0A8V0YQJ5-1|A0A8V0YQJ5_CHICK Isoform 1 of Tetratricopeptide repeat and ankyrin repeat containing 1 OS=Gallus gallus OX=9031 GN=TRANK1 PE=1 SV=1 CANONICAL=A0A8V0YQJ5-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YQJ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQJ5/entry#A0A8V0YQJ5-1", "sequence": { "sequence": "MVEMICSPDFILDEPDQEHDPERVRCTPNMWRTFTKTAPESMDAMEYAQFMKQDGNQDFKNGNYALAIRKYDQALYMLVQLRQWGLCSGDIAVLYCNKSTCLYNLGKWREAMLSAFESLRWDPQYVKAYYRAGHSLIMLSNAYNAVCMFHRGLTLLNASVDQAQVADFIAGIFTSVNDERVLPPTFYPAYDYIFSARFDALIWQSVMEKLAQKGKWQSFLLLLSKKKDLPTNLRVNQLPLKNLFETFELYGCDETMQNVAELVKWLISIGAKVESIGVYPLHAVIRLCIKAKKNHIFRWLLSQRPDLKDRINQQDRDGCTLLHIVASSSDYSRKRSQTEDVLMLLNFGVDPTIPDARSRNVIDILKKNKNFDAVKAVSNHIEKHTSSSVELEDEDRRRAVVDSFLDALEQFVKFCSFENGLHHKNILKEDVFQRFLKLLSSVKEIPDGVVCNISQACANSIVKLLLKKQMWHEVLLLLTGKANGENASDGGLLKACSLSDVDIGSIIQQCDRLDERVHLIRCLVERGALPDGTGAKSEIPLQICLKKNYIELVYLLLTKGADPRNISFAKGDTPLHAAVHICLDKRDGTGINILNYLLDLFASRPSDFPYLNPNVQDDNGNTVMHVIFQRGFSKQAKRIMDSLAKFDVNFNIKNKLGRDVRHRIKKNDPLLLAWNTAVSEKKKYRQDIAGQLVKTPKPTPASDVSQPKNAGRSSSGSLLKVPSGNTARNDVKTQSSVKTKNDQLSKQEMEKIKNPLTMQESLVQEIAALIQQLKWGDALRKDNSVVQKQSSGQTNLEEGKSASLQLSGSAVYSEGRGDDREKKKGVQEFSVGLSNGEKEAPDEEMILDIEAYVQEFDNMTWEIECTPEALKTLGSKDVPHYLKTKTIMTIKRLGNGEWTKGLQKPLKHLKADIQLYEAKLGKGARMLWELAIDFSPRCSESAEKIMETEQTKSLPEKSGRVYTEMIRIWAIVLDHCKLNRVLDNICLSYNRGLSCILRKKLKGINEGHQNYNVTMHKRVPRCYVEDLEREKSKEHTIPEYFPPASAAEMEYNIMKFHSFSTNMALNIINDVHSAVEYPFRVGELEYAVIDLNPKPMEPIILIGRSGTGKTTCCLYRLWKKFYSYWEKSTMANSPLLERQTWRQRQCSDVEKARLENEECEEKQDNDDSSEEQVSEEQDQDSEDEEVATGTSDAETSPCDDHEEGQKCNSEEPNTLEHLHQIFVTKNPVLCQEVQKNFIELSKSSKVTSHFKPLEPNVHRLQDVKDENFPLFITSKQLLLLLDASLPDPFFPRNEDGSLKRTIVGWSPQEELVIPNWQDEDEECNAEAEDGDEERTADGYSRESDPRTFVTYDLFANEIWPKMIKGKSLYNPALVWKEIKSFLKGSFEALSCFGGKLTEEQYKKLGRKRSPNFTEDRSEIYHLFCLYQQIRSQRGYFDEEDLLYNLSQRLSQLGELPWSIHEFYGDEIQDFTQAELALLMKCINDPNSMFLTGDTAQSIMKGVAFRFSDLRSLFHYASKNTVDKKQRVRKPKRIYQLYQNYRSHSGILSLASGVVDLLQYYFPESFDRLPKDCGLFDGPKPTVLESCSFSDLAILLRGNKRKTQPIEFGAHQVVLVANETAKEKIPEELSLALVLTVYEAKGLEFDDVLLYNFFTDSEASKEWKIISSYTPDSDVQVGSKLLIEMPLEDATAMQKRPTSFNAEMYKMLNGELKQLYTAITRARVNLWIFDENSDKRAPAFKYFIKRGFVQVVKTDENKDLDDSMFAKTSSPEEWIAQGDYYAKHQFWEVAAKCYQKGGAAEKSKLALAHDAVLKVHSKKSSPREKQMEYMTLAKTYLECGESKLSLKCLFQSKEFRLCAELCKKLGKMKDAAVYYQKNQCYKEASECYEQIEEFDLAIKMYCQEELYEEAAKAVERYEEMLNARGQMVSKLSCTANQLYLEAAAKYLSVNRIEEMMQVLSKLDIEDQLEFLKSRGCLHQTADLLKREGRQEEAAKLMKQHGYALEAANLTAIKEFRASCLLAAVRAGTTHCSESNLVDREIMLREALELCEQTNQKSGIAEALFLQGAPKRDFTKLSNAYFQFLSVNHSAGAVEVLFVLSRCSAPSQEILCKATHGLMALLDLVKSLKKATTNVEKDMVKSCFAYFGIIPTGDSCCQVSQNEAEPILKFLLDKASLKERKTKGNFSVSTEAVKSALKQHLLSRLCSITHELLNKHYPDICMKFIVGLNCEDSTCGDFHKPLMRHEARMVFQCKMNLAAINGLLLEATHTFPKELLSHCKSFDGLLTSDKYVSCKALLETFFPNHFHLRILSENPKACKEILGFSNITSKPCRALLNEYISFKFKDEDARARRESSDLWLSAMKVFLLSSGYPEEFEKLLFKEEDDYNRELNLALSKAKSSPKSKSHGGKIKGIDGRHGMLQPDKKTENAGRTHLCFIRLLQSSFEQFYVYKNPESCKRLFFRFMNVLVKKCTRYLIPSIGNTVMLLEFQYIICCAVLMRLNKNVTLCLPKSYIALVHYWDFLFRNKGRSKEFTETFSIIQEYRPKDILVAEQNFRFHLCYLAKILCGVHENFSVLLDAFEDPDCVTSGEAERTVVLSLVMILNADQVQNSMCKYLLSQLFPEIKGMLKAMRKDSPSKVPVRLLKVVEQVAAASGVREVAASLQELLIERDEEYLFDCRWRWDSVYTQGYAPIRGILYENVNFDRFIASLDKTEYADEIEKELESDQCLEDQKDPLEVIALNKQQKQEQKASALRHLYRVFHFVFVCMRWKRKACCKAEPVAVEGEEFLSDIFKKADIDQTQCDLCGVRFIQSSENYFSQTESVEADTSEAVTPTEEKMQVEGNAIIAASEAYMEHRNTDKHRNNNAAYKNYADFFRRWIDPKIRDGLDVVEAITERTYTQDHLAYKEGSNLCQRKIKENIKKISDAVEEIYERKAWAEAEEIITEHANKLFAVTDEAYKWLKKMDLQRIKEEDFVHDRDLENEVEDESMAFEELAYKKPSRKKGRYGKW", "length": 3008, "header": "tr|A0A8V0YQJ5-1|A0A8V0YQJ5_CHICK Isoform 1 of Tetratricopeptide repeat and ankyrin repeat containing 1 OS=Gallus gallus OX=9031 GN=TRANK1 PE=1 SV=1 CANONICAL=A0A8V0YQJ5-1" }, "locus": { "chromosome": "2", "start_pos": 45911710, "end_pos": 45871324, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010040162.1", "url": "https://www.ensembl.org/id/ENSGALT00010040162.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023285.1", "url": "https://www.ensembl.org/id/ENSGALP00010023285.1" } ] } }, { "isoform_ac": "A0A8V0YWX2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQJ5/entry#A0A8V0YWX2-1", "sequence": { "sequence": "MDAMEYAQFMKQDGNQDFKNGNYALAIRKYDQALYMLVQLRQWGLCSGDIAVLYCNKSTCLYNLGKWREAMLSAFESLRWDPQYVKAYYRAGHSLIMLSNAYNAVCMFHRGLTLLNASVDQAQVADFIAGIFTSVNDERVLPPTFYPAYDYIFSARFDALIWQSVMEKLAQKGKWQSFLLLLSKKKDLPTNLRVNQLPLKNLFETFELYGCDETMQNVAELVKWLISIGAKVESIGVYPLHAVIRLCIKAKKNHIFRWLLSQRPDLKDRINQQDRDGCTLLHIVASSSDYSRKRSQTEDVLMLLNFGVDPTIPDARSRNVIDILKKNKNFDAVKAVSNHIEKHTSSSVELEDEDRRRAVVDSFLDALEQFVKFCSFENGLHHKNILKEDVFQRFLKLLSSVKEIPDGVVCNISQACANSIVKLLLKKQMWHEVLLLLTGKANGENASDGGLLKACSLSDVDIGSIIQQCDRLDERVHLIRCLVERGALPDGTGAKSEIPLQICLKKNYIELVYLLLTKGADPRNISFAKGDTPLHAAVHICLDKRDGTGINILNYLLDLFASRPSDFPYLNPNVQDDNGNTVMHVIFQRGFSKQAKRIMDSLAKFDVNFNIKNKLGRDVRHRIKKNDPLLLAWNTAVSEKKKYRQDIAGQLVKTPKPTPASDVSQPKNAGRSSSGSLLKVPSGNTARNDVKTQSSVKTKNDQLSKQEMEKIKNPLTMQESLVQEIAALIQQLKWGDALRKDNSVVQKQSSGQTNLEEGKSASLQLSGSAVYSEGRGDDREKKKGVQEFSVGLSNGEKEAPDEEMILDIEAYVQEFDNMTWEIECTPEALKTLGSKDVPHYLKTKTIMTIKRLGNGEWTKGLQKPLKHLKADIQLYEAKLGKGARMLWELAIDFSPRCSESAEKIMETEQTKSLPEKSGRVYTEMIRIWAIVLDHCKLNRVLDNICLSYNRGLSCILRKKLKGINEGHQNYNVTMHKRVPRCYVEDLEREKSKEHTIPEYFPPASAAEMEYNIMKFHSFSTNMALNIINDVHSAVEYPFRVGELEYAVIDLNPKPMEPIILIGRSGTGKTTCCLYRLWKKFYSYWEKSTMANSPLLERQTWRQRQCSDVEKARLENEECEEKQDNDDSSEEQVSEEQDQDSEDEEVATGTSDAETSPCDDHEEGQKCNSEEPNTLEHLHQIFVTKNPVLCQEVQKNFIELSKSSKVTSHFKPLEPNVHRLQDVKDENFPLFITSKQLLLLLDASLPDPFFPRNEDGSLKRTIVGWSPQEELVIPNWQDEDEECNAEAEDGDEERTADGYSRESDPRTFVTYDLFANEIWPKMIKGKSLYNPALVWKEIKSFLKGSFEALSCFGGKLTEEQYKKLGRKRSPNFTEDRSEIYHLFCLYQQIRSQRGYFDEEDLLYNLSQRLSQLGELPWSIHEFYGDEIQDFTQAELALLMKCINDPNSMFLTGDTAQSIMKGVAFRFSDLRSLFHYASKNTVDKKQRVRKPKRIYQLYQNYRSHSGILSLASGVVDLLQYYFPESFDRLPKDCGLFDGPKPTVLESCSFSDLAILLRGNKRKTQPIEFGAHQVVLVANETAKEKIPEELSLALVLTVYEAKGLEFDDVLLYNFFTDSEASKEWKIISSYTPDSDVQVGSKLLIEMPLEDATAMQKRPTSFNAEMYKMLNGELKQLYTAITRARVNLWIFDENSDKRAPAFKYFIKRGFVQVVKTDENKDLDDSMFAKTSSPEEWIAQGDYYAKHQFWEVAAKCYQKGGAAEKSKLALAHDAVLKVHSKKSSPREKQMEYMTLAKTYLECGESKLSLKCLFQSKEFRLCAELCKKLGKMKDAAVYYQKNQCYKEASECYEQIEEFDLAIKMYCQEELYEEAAKAVERYEEMLNARGQMVSKLSCTANQLYLEAAAKYLSVNRIEEMMQVLSKLDIEDQLEFLKSRGCLHQTADLLKREGRQEEAAKLMKQHGYALEAANLTAIKEFRASCLLAAVRAGTTHCSESNLVDREIMLREALELCEQTNQKSGIAEALFLQGAPKRDFTKLSNAYFQFLSVNHSAGAVEVLFVLSRCSAPSQEILCKATHGLMALLDLVKSLKKATTNVEKDMVKSCFAYFGIIPTGDSCCQVSQNEAEPILKFLLDKASLKERKTKGNFSVSTEAVKSALKQHLLSRLCSITHELLNKHYPDICMKFIVGLNCEDSTCGDFHKPLMRHEARMVFQCKMNLAAINGLLLEATHTFPKELLSHCKSFDGLLTSDKYVSCKALLETFFPNHFHLRILSENPKACKEILGFSNITSKPCRALLNEYISFKFKDEDARARRESSDLWLSAMKVFLLSSGYPEEFEKLLFKEEDDYNRELNLALSKAKSSPKSKSHGGKIKGIDGRHGMLQPDKKTENAGRTHLCFIRLLQSSFEQFYVYKNPESCKRLFFRFMNVLVKKCTRYLIPSIGNTVMLLEFQYIICCAVLMRLNKNVTLCLPKSYIALVHYWDFLFRNKGRSKEFTETFSIIQEYRPKDILVAEQNFRFHLCYLAKILCGVHENFSVLLDAFEDPDCVTSGEAERTVVLSLVMILNADQVQNSMCKYLLSQLFPEIKGMLKAMRKDSPSKVPVRLLKVVEQVAAASGVREVAASLQELLIERDEEYLFDCRWRWDSVYTQGYAPIRGILYENVNFDRFIASLDKTEYADEIEKELESDQCLEDQKDPLEVIALNKQQKQEQKASALRHLYRVFHFVFVCMRWKRKACCKAEPVAVEGEEFLSDIFKKADIDQTQCDLCGVRFIQSSENYFSQTESVEADTSEAVTPTEEKMQVEGNAIIAASEAYMEHRNTDKHRNNNAAYKNYADFFRRWIDPKIRDGLDVVEAITERTYTQDHLAYKEGSNLCQRKIKENIKKISDAVEEIYERKAWAEAEEIITEHANKLFAVTDEAYKWLKKMDLQRIKEEDFVHDRDLENEVEDESMAFEELAYKKPSRKKGRYGKW", "length": 2967, "header": "tr|A0A8V0YWX2-1|A0A8V0YWX2_CHICK Computationally mapped isoform of Tetratricopeptide repeat and ankyrin repeat containing 1 OS=Gallus gallus OX=9031 GN=TRANK1 PE=1 SV=1 CANONICAL=A0A8V0YQJ5-1" }, "locus": { "chromosome": "2", "start_pos": 45909801, "end_pos": 45871324, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010040156.1", "url": "https://www.ensembl.org/id/ENSGALT00010040156.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023282.1", "url": "https://www.ensembl.org/id/ENSGALP00010023282.1" } ] } }, { "isoform_ac": "A0A8V0YYU0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQJ5/entry#A0A8V0YYU0-1", "sequence": { "sequence": "MSFLLLLSKKKDLPTNLRVNQLPLKNLFETFELYGCDETMQNVAELVKWLISIGAKVESIGVYPLHAVIRLCIKAKKNHIFRWLLSQRPDLKDRINQQDRDGCTLLHIVASSSDYSRKRSQTEDVLMLLNFGVDPTIPDARSRNVIDILKKNKNFDAVKAVSNHIEKHTSSSVELEDEDRRRAVVDSFLDALEQFVKFCSFENGLHHKNILKEDVFQRFLKLLSSVKEIPDGVVCNISQACANSIVKLLLKKQMWHEVLLLLTGKANGENASDGGLLKACSLSDVDIGSIIQQCDRLDERVHLIRCLVERGALPDGTGAKSEIPLQICLKKNYIELVYLLLTKGADPRNISFAKGDTPLHAAVHICLDKRDGTGINILNYLLDLFASRPSDFPYLNPNVQDDNGNTVMHVIFQRGFSKQAKRIMDSLAKFDVNFNIKNKLGRDVRHRIKKNDPLLLAWNTAVSEKKKYRQDIAGQLVKTPKPTPASDVSQPKNAGRSSSGSLLKVPSGNTARNDVKTQSSVKTKNDQLSKQEMEKIKNPLTMQESLVQEIAALIQQLKWGDALRKDNSVVQKQSSGQTNLEEGKSASLQLSGSAVYSEGRGDDREKKKGVQEFSVGLSNGEKEAPDEEMILDIEAYVQEFDNMTWEIECTPEALKTLGSKDVPHYLKTKTIMTIKRLGNGEWTKGLQKPLKHLKADIQLYEAKLGKGARMLWELAIDFSPRCSESAEKIMETEQTKSLPEKSGRVYTEMIRIWAIVLDHCKLNRVLDNICLSYNRGLSCILRKKLKGINEGHQNYNVTMHKRVPRCYVEDLEREKSKEHTIPEYFPPASAAEMEYNIMKFHSFSTNMALNIINDVHSAVEYPFRVGELEYAVIDLNPKPMEPIILIGRSGTGKTTCCLYRLWKKFYSYWEKSTMANSPLLERQTWRQRQCSDVEKARLENEECEEKQDNDDSSEEQVSEEQDQDSEDEEVATGTSDAETSPCDDHEEGQKCNSEEPNTLEHLHQIFVTKNPVLCQEVQKNFIELSKSSKVTSHFKPLEPNVHRLQDVKDENFPLFITSKQLLLLLDASLPDPFFPRNEDGSLKRTIVGWSPQEELVIPNWQDEDEECNAEAEDGDEERTADGYSRESDPRTFVTYDLFANEIWPKMIKGKSLYNPALVWKEIKSFLKGSFEALSCFGGKLTEEQYKKLGRKRSPNFTEDRSEIYHLFCLYQQIRSQRGYFDEEDLLYNLSQRLSQLGELPWSIHEFYGDEIQDFTQAELALLMKCINDPNSMFLTGDTAQSIMKGVAFRFSDLRSLFHYASKNTVDKKQRVRKPKRIYQLYQNYRSHSGILSLASGVVDLLQYYFPESFDRLPKDCGLFDGPKPTVLESCSFSDLAILLRGNKRKTQPIEFGAHQVVLVANETAKEKIPEELSLALVLTVYEAKGLEFDDVLLYNFFTDSEASKEWKIISSYTPDSDVQVGSKLLIEMPLEDATAMQKRPTSFNAEMYKMLNGELKQLYTAITRARVNLWIFDENSDKRAPAFKYFIKRGFVQVVKTDENKDLDDSMFAKTSSPEEWIAQGDYYAKHQFWEVAAKCYQKGGAAEKSKLALAHDAVLKVHSKKSSPREKQMEYMTLAKTYLECGESKLSLKCLFQSKEFRLCAELCKKLGKMKDAAVYYQKNQCYKEASECYEQIEEFDLAIKMYCQEELYEEAAKAVERYEEMLNARGQMVSKLSCTANQLYLEAAAKYLSVNRIEEMMQVLSKLDIEDQLEFLKSRGCLHQTADLLKREGRQEEAAKLMKQHGYALEAANLTAIKEFRASCLLAAVRAGTTHCSESNLVDREIMLREALELCEQTNQKSGIAEALFLQGAPKRDFTKLSNAYFQFLSVNHSAGAVEVLFVLSRCSAPSQEILCKATHGLMALLDLVKSLKKATTNVEKDMVKSCFAYFGIIPTGDSCCQVSQNEAEPILKFLLDKASLKERKTKGNFSVSTEAVKSALKQHLLSRLCSITHELLNKHYPDICMKFIVGLNCEDSTCGDFHKPLMRHEARMVFQCKMNLAAINGLLLEATHTFPKELLSHCKSFDGLLTSDKYVSCKALLETFFPNHFHLRILSENPKACKEILGFSNITSKPCRALLNEYISFKFKDEDARARRESSDLWLSAMKVFLLSSGYPEEFEKLLFKEEDDYNRELNLALSKAKSSPKSKSHGGKIKGIDGRHGMLQPDKKTENAGRTHLCFIRLLQSSFEQFYVYKNPESCKRLFFRFMNVLVKKCTRYLIPSIGNTVMLLEFQYIICCAVLMRLNKNVTLCLPKSYIALVHYWDFLFRNKGRSKEFTETFSIIQEYRPKDILVAEQNFRFHLCYLAKILCGVHENFSVLLDAFEDPDCVTSGEAERTVVLSLVMILNADQVQNSMCKYLLSQLFPEIKGMLKAMRKDSPSKVPVRLLKVVEQVAAASGVREVAASLQELLIERDEEYLFDCRWRWDSVYTQGYAPIRGILYENVNFDRFIASLDKTEYADEIEKELESDQCLEDQKDPLEVIALNKQQKQEQKASALRHLYRVFHFVFVCMRWKRKACCKAEPVAVEGEEFLSDIFKKADIDQTQCDLCGVRFIQSSENYFSQTESVEADTSEAVTPTEEKMQVEGNAIIAASEAYMEHRNTDKHRNNNAAYKNYADFFRRWIDPKIRDGLDVVEAITERTYTQDHLAYKEGSNLCQRKIKENIKKISDAVEEIYERKAWAEAEEIITEHANKLFAVTDEAYKWLKKMDLQRIKEEDFVHDRDLENEVEDESMAFEELAYKKPSRKKGRYGKW", "length": 2792, "header": "tr|A0A8V0YYU0-1|A0A8V0YYU0_CHICK Computationally mapped isoform of Tetratricopeptide repeat and ankyrin repeat containing 1 OS=Gallus gallus OX=9031 GN=TRANK1 PE=1 SV=1 CANONICAL=A0A8V0YQJ5-1" }, "locus": { "chromosome": "2", "start_pos": 45906738, "end_pos": 45871324, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010040152.1", "url": "https://www.ensembl.org/id/ENSGALT00010040152.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023278.1", "url": "https://www.ensembl.org/id/ENSGALP00010023278.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1719, "start_aa": "Thr", "end_pos": 1719, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1719", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 699, "start_aa": "Thr", "end_pos": 699, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr699", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:420728", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420728", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0AAA9SEL9-1", "protein_name": "Tetratricopeptide repeat and ankyrin repeat containing 1", "gene_name": "TRANK1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MESFWPLLQRMDPTAYAELLKESGNQGFKSGNFSLAIRKYDEAIQILLQLYQWGSGDWEVQGPGGGQFNSWVPPRDLAVLLCNKSNAFYSLGKWNEAYGAAKECLQWDPTYVKGYYRAGYSLLGLCQPYEAARMFFEGLRLVRSSQDKTQIADFLVAVFTTMGSDPIVLQSFLPCFDRIFTTGFSNEVWQSVIEKLAKKGLWHSFLLLSVKKDRLPRNLHVPDLSLKSLFEKYVCVGRYEKVEQVPTLVQWLVCMGANVESIGPYPLHTLMRLCIQAGESHLFRWLMDYKPELKGRINQKDEDGCTVLHVVAAHSPGYLTKRQTEDVQMLLRFGADPTLVDRQSRSAVDVLKRNKNFRAIDKINSHLEKLAACSKDLSELSTGEGPANEGDIFQKVCEQLVTYMNSGSHLLQKNFMKQEVVQKFLRILSSLQEIPPDLVYDIDRDCANTFLKFLLEKQKWPEVLLLLTRKVSGQPPLGDCLIKDCDLSTLDLCAILPHLKAWDQRRTLLLDCLIDHGALLEGLQSSQETPLAVCMKHEDFDMAFVLLTKGADPRNISLTEGDTPLHAALHIFLDIKADIGFNFLSHLLDLFWSKPEEFSYLNPNMQDGSGNTLMHILFQKGMLKRTGKLVGLLAKFDINLNLKNKEGKDARYRVKKNDPLLLAWNKALMETRRRGRQDAAAHPGKPPRPAAPAHTAQVKGSSKLLPGAVRAPPKEARVPDSWETLPDAQAPRLEPEAARPCSQRDCLVQDITALIQQLELNSSLPEDCPQGPETLETGAGTEGEKEELQGAPGAGGSDCSGNNPGALEAAEGHVQAGLSAAQLLPEGSRGTEGSDDQDDWSVSEMDICLLDFENMTWEIECTSEMLKKLSSKVMSKVMKKKIILAIQKLGNGEWTPGLRKRLRNLKGSIQLFEAKLDKAARMLWELAIDFSPRCSENPEKIIAAERSMHPTEKSGRVYTEIIRIWDIVLDHNKLSYSIQAICSAYNRGLSCILRKKLKGINKGPVSANMKIQKWIPRCYVEDTEAEKGGARAEPEYFPPASAVETEYNIMKFHSFSTNMASNILNDTTATVEYPFRVGELEYAVIGLNPRPLEPIILIGRSGTGKTTCCLYRLWKKFHGYWEKAQQAGSPLLAKQIWLKRRLELEPRKEGQGGEEEEEEEEEGEEEEEEGSVEVGTVGCLEEEQESEACAEGAGGEPGGPGQGEEEPAPQEPPQLEHLHQIFVTKNHVLCQEVQRNFVELSKSTKATSHYKPLEPNVHKLQDLRDENFPLFVTSKQLLLLLDASLPKPFFLRNEDGSLKRSIVGWSTQEELTITNWQEEEEEAEADGDYSEEEKTVETRPSDSDPRVYVTFEVFVNEIWPKMIKGKTSYNPALIWKEIKSFLKGSFEALSCPGGRLTEEAYKQLGRKRCPNFKEDRSEIYGLFCLYQQIRSHKGYFDDEDVLYNLSRRLSKLKVLPWSIHELYGDEIQDFTQAELALLMKCINDPNAMFLTGDTAQSIMKGVAFRFSDLRSLFHYASRNAVDKQCAVRKPKKIHQLYQNYRSHSGILNLASGVVDLLQFYFPESFDRLPRDSGLFDGPRPIVLESCSVSDLAILLRGNKRKTQPIEFGAHQVILVANEMAKEKIPEELGLALVLTVYEAKGLEFDDVLLYNFFTDSEAYKEWKIISSFTPSSSGCREESQPMIEVPLDNCSSSQGRAVTMNPEMYKLLNGELKQLYTAITRARVNLWIFDENPEKRAPAFKYFMKRKFVEVVKTDENKDLDDSMFVKTSTPGEWIAQGDYYAKHQCWKVAAKCYQKGGALEKEKLALAHNTALNMKSKKVSLKEKQVEYLELAKTYLECKEPKLCLKCLSYAKEFQLCAQLCERLGKVRDAAYFYKRSQCYKDASRCFEQIQEFDLALKMYCQEELFEEAAMAVEKYEEMLRAKALPVSKLTYSASQFYLEAAAKYLSMNKTKEMMAVLSKLDIEDQLVFLTSRKRLTEAADLLNREGRREEAALLMKQHGCLLEAARLTADKDFQASCLLAAARLNVARDSDVDLTKAILREALDLCHQTNQVSGIAQAHFLQGVIMRDFLKLKDAFLKFDTLNHSAGAVEALYEATSHCEVQPEDVLALAPGGLGVLLDLVRALRRVTTNAEKEMVKSCFEFFGILQVDAKYCQIAQNDPGPILRIISDLDLNLKEKKTKDHFLIMMDQVKLALNKHLLSRLCQITESLLAKTYPGVCMKFLVGLKCEDGRCEDFHRPLRRHEAKCLVQSKIHLVAIKGLLLEAKRVFSKVLAEGLEEIDYILSLDKHGLCESLLNVVFPKHFHQRVLSENPMACKEVLKPHYKSFRSYRSALKEYIHVLFQNERARSRRESTDLWLSAMQAFLLSSSYPDELDKLLYQEEDQYNRELKALQSEQEKRGRDRGSRMKGIEGKFGMLAPNKDDESAEKPHLCFIRLLQDSIRQFYVCRNPEDYKRRFFRFMNVLVKRCKEPLIPSIGNTVALLELQFIHCGVVLARLSKNAVLCLPKSYIALLHYWEFLFSKKDQEPGDVFAIIQEYRPKDLTRAIQEFRFHLSYLVKVLCGCENANFNVLLDAFSDIDYVVSGEAERTLVLCLVMLVNTKGVLQPSCKPLLSSQFQELEARLQLLSIECPGRVPERLLRVVKQVQLAVNVKSVAEALQDLLFERDEEFLMDCHWQWDSGHAKGTAVRGLYHEEVRLNRLFSMDPVGYLAEPEYEVGQDEPEELALEGDHLLDAVLSQKLRRASIRQKMRRVCLVVSLCIRWRRGRAGGQAEHFREEGREPAAGNFKKADVDRTQCDLCGVKFARGPENYFTPDQAFEGAAPEAVALSGTELEDEQGWERSSESYEQHILLESHQSQQVAYQRYLEFFREKVDPAMEEGKLVVQDMEQSAWGRKHLGSKEHSHILQRKVQENIKKVSDSVEDLYRRKAWADAEEVMARLVNILIPSVRDAQEWLRKTELHQEEGVIQEDVYENEVEDFGELRPRRRPRKCAKKKH", "length": 2996 }, "evidence": [ { "id": "A0A8V0YQJ5", "url": "https://omabrowser.org/oma/group/A0A8V0YQJ5/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "D3ZSG2-1", "protein_name": "Tetratricopeptide repeat and ankyrin repeat containing 1", "gene_name": "Trank1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASRTAGRRWPPRRRSSRRGPTPRSRAPGAKLSAPEAGPPRRGPLPRGGAGRDTLLGAKATPSSPATRRYVTALGPPQPRGNTDSACAALPQPVPHEPREAAFRLVPGSERRASVSPARIPRRRRRVPAMWDPRAARTPPRELAVLLCNKSNAFYSLGKWDEAFLAAKECLQWDPTYVKGYYRAGYSLLHLLQPYEAARMFFEGLRLLQRSPDQVQVPDFLVGIFTTMSSDSIVLQSFLPCFDHIFSTGFSTEVWQSVIQKLAKKGLWHQSFLLLSAKKDRLPSNIHVSELSLQSLFEKYVFIGLYEKMEQVPKLVQWLISIGANIETIGPSPLHALMRLCIQSRESQLFRWVMEYKPEWKEHINYRDDAGCTVLHVAAAHFPGYTIKRQTEDVQMLLSFGADPTLLDGHARSAVDVLKRNRNFRAVDKINSHLEKLASSSKGRSEISAGLDVNRDCATTFVKFLLERQKWPEVLLLLTRKASGQHQLRNGLIKDCDLSDLDICTVIPHLSAWDQRKTQLLSRLIDSGALPEGLQDSQDRPLLMCLRHEDFDLAFLLLTKGADPRSVSLMEGDTPLHAALHIFLDINADIGFNFLSHLLDLFLSNPTEFYYLNPNVQDSNGNTLMHLLFQKGMLKRTKKLIELLVKFDINFNLKNKAGKGVRHRIKKNDALLLAWNKALTESRRKNRQDPAAHLGRLSRSSALGHTSQLKSQTSFKSLPCSTADRTLSKGVTEILPDVQVTRQEPEAMRTRSLRDRLVQDITVLIQQIELDMSLPQDYPQQGSPKMAAGMEGKKDKLQRTQSMGSSGSSRDNPVASEAGDGHAQAGPGALQLAPVGNRLRVAGGNQDNWTMQEIQACLQDFDNMTWEIECTSEMLKKLSSKVMTKVIKKKIILAIQQLGNGEWTQGLQKRLKHSKGNIQLFEAKLDKGARMLWELAIDFSARCSENSEKIMGTERNTYSMEKSGRVYTEIIRIWDIVLDHCKLSDSIMAICSAYTRGLSCVLRKKLKGINKGQVSANMKIQKRIPRCYVEDTEAEKSIEQADPEYFPPASAVETEYNIMKFHSFSTSMALNILNDMTATVEYPFRVGELEYAVIDLNPKPLEPIILIGRSGTGKTTCCLYRLWKKFHVYWEKAEQAGSPLLSKQILPKRRLEVEPGKEGPGQEEEENEEEEGSIKVETVDSTEEEQESEACAGGTVESAGDSQAAEGCVPDHPHQLEHLHQIFVTKNHVLCQEVQRNFIELSKSTKATSHYKPLDPNVHKLQDLRDENFPLFVTSKQLLLLLDASLPKPFFLRNEDGSLKRTIVGWSTQEEFSIPSWEEDEDEVEADGNYSEEEKTTETQTGDSDPRVYVTFEVFTNEIWPKMIKGRSSYNPALIWKEIKSFLKGSFEALSCPHGRLTEEAYQKLGRKRSPNFKEDRSEIYSLFCLYQQIRSQKGYFDEEDVLYNLSWRLSKLRVLPWSIHELYGDEIQDFTQAELALLMKCINDPNAMFLTGDTAQSIMKGVAFRFSDLLSLFHYASRNTVDKQCAVRKPKRIHQLYQNYRSHSGILNLASGVVDLLQFYFPESFDRLPRDSGLFDGPKPTLLDSCSVSDLAILLRGNKRKTQPIEFGAHQVILVANEMAKEKIPEELGLALVLTVYEAKGLEFDDVLLYNFFTDSEAYKEWKIISSFIPSSDSREENCPLLDVPLEKSSSSQARSLMVNPEMYKLLNGELKQLYTAITRARVNLWIFDENLEKRAPAFKYFIRRDFVQVVKTDENKDFDDSMFVKTSTPDEWIIQGDYYAKHQCWKVAAKCYQKGDAFEKEKLALAHYTALNMKSKKFSPKEKELQYLELAKTYLECNEPKLSLKCLSYAKEFQLSAQLCERLGKIRDAAYFYKRSQCFKDAFRCFEQIQEFDLALRMYCQEELFEEAAIAVEKYEEMLKNKTFPVPKLSYSASQFYLEAAAKYLSANKSKEMMAVLSKLDVEDQLVFLKSRKRLAEAAELLNREGRKEEAALLMKQHGCLLEAARLTANKDFQASCLLGVARLNVARDSDVEHTKAILREVLDLCYQTGHLAGIAEAQFLQGIILRDFQKLRDAFIKFDMLNHSAGMVEALYEAASQCESESQKVLALAPGGLEVLLNLVRALKNVTNNAEKEMVKSCFEFFGIFQVDAKYCQIAQNDPGPILRIILDLDLTLSEKKTKDHFLVLTDQVKLALNKHLLGRLCQITQILLGKTYPGICMRFIVGLKCEDEHCEDFHRPLRRCEAKCMVQSKMHLVAINGLLLEAKKVFPNVLAEELEEIDYILSPDTYGLCKSFLNLLFPRHFHQRVLSENPMACKEILKANYKFFRSYRFALKEYIHDLFQKESAHSRRESTDLWLSAMQAFLLSSSYPDEFEKLLHQEEDSYNRELKVLESDREDRGRGRGSRMKGIEGKFGMLVPNREDENVERSYLCFIRLLESSMDQLYVHRNPEDYKRLFFRFMNVLIKRCKAPLVPSIINTVVLLELQFVHCGAVLARLWKNAVLCLPKSYIALLHFWEFLSSKKDRESGDVFSIIQEYKPKDVTRAVRDFRFHLSYLVKVLCGYENMNFNVLLDSFSEIDYVISGEAERTLVLCLVMLVNAEEVLHPFCKPLLFRHFREIQKRLQLMSMDWPGQVPKRLQKVVQRVLMAVSVKSVAEALQDLLFERDEEYLVDCHWRWDSVHAKGTVVRGLCHEEVRLNRLLCTGPMDQFADSDWDFGEDETHELDELALEDRDNFLAAILSQKQRKALIQRKLRTACLVVSLCISWRRWIQTEHSREEDRELRPGNFKRADVDRTQCDLCGVKFARSPESYFSAGKAFEGAATEAVIISRAELEGRECRERVSESYEQHIRLEGHRRQQAAYQKYLDFFHEKVDPIIEEGKVVVQDVEQSVWIRSHLGSKEQSHMLQRKVQEHIRKVSDLVEELYRRKAWAEAEEVMTRQVKILTLSVKNAQEWLKKTELRLKDEGTVQDEEYENEVEDFGELCPRRRARKCGKQRKY", "length": 2999 }, "evidence": [ { "id": "A0A8V0YQJ5", "url": "https://omabrowser.org/oma/group/A0A8V0YQJ5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O15050-1", "protein_name": "TPR and ankyrin repeat-containing protein 1", "gene_name": "TRANK1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MWDPRAARVPPRDLAVLLCNKSNAFFSLGKWNEAFVAAKECLQWDPTYVKGYYRAGYSLLRLHQPYEAARMFFEGLRLVQRSQDQAPVADFLVGVFTTMSSDSIVLQSFLPCFDHIFTTGFPTEVWQSVIEKLAKKGLWHSFLLLSAKKDRLPRNIHVPELSLKSLFEKYVFIGLYEKMEQVPKLVQWLISIGASVETIGPYPLHALMRLCIQARENHLFRWLMDHKPEWKGRINQKDGDGCTVLHVVAAHSPGYLVKRQTEDVQMLLRFGADPTLLDRQSRSVVDVLKRNKNFKAIEKINSHLEKLATCSKDLSGFSNGDGPTSENDIFRKVLEQLVKYMNSGNRLLHKNFLKQEVVQRFLRLLSTLQEIPPDLVCDINQDCATTVFKFLLEKQRWPEVLLLLTRKVSGEPPLGDCLIKDCNFSDLDICTIIPHLSTWDQRKKQLLGCLIDSGALPDGLQESQERPVVTCLKHEDFELAFLLLTKGADPRAISLTEGDTPLHAALHIFLEIKADIGFSFLSHLLDLFWSNPTEFDYLNPNVQDSNGNTLMHILFQKGMLKRVKKLLDLLVKFDINFNLKNKEGKDARHRIKKNDSLLLAWNKALMENRRRSRQDSAAHLGKLSKSTAPGHTSQLKSQGSFKSVPCGATARTLPEGSAVPDSWETLPGTQVTRKEPGALRPCSLRDCLMQDITVLIQQVEVDPSFPEDCLQSSEPLEAGAGKEGKKDDKPTLGAGAPDCSEVGEGHAQVGLGALQLVPDDNRGKEGNDDQDDWSTQEIEACLQDFDNMTWEIECTSEMLKKLSSKVMTKVIKKKIILAIQQLGNGEWTQGLQKRLKHLKGSIQLFEAKLDKGARMLWELAIDFSPRCSENPEKIIATEQNTCAMEKSGRIYTEIIRIWDIVLDHCKLADSIKAICNAYNRGLSCVLRKKLKGINKGQVSANMKIQKRIPRCYVEDTEAEKGREHVNPEYFPPASAVETEYNIMKFHSFSTNMAFNILNDTTATVEYPFRVGELEYAVIDLNPRPLEPIILIGRSGTGKTTCCLYRLWKKFHVYWEKAEQAGSPLLAKQVWLKRRLEVEPGKESPGGEEEEEEEDEEEEDSIEVETVESIDEQEYEACAGGAGVEPAGDGQAAEVCAPEHPHQLEHLHQIFVTKNHVLCQEVQRNFIELSKSTKATSHYKPLDPNIHKLQDLRDENFPLFVTSKQLLLLLDASLPKPFFLRNEDGSLKRTIIGWSAQEESTIPSWQEDEEEAEVDGDYSEEDKAVEMRTGDSDPRVYVTFEVFKNEIWPKMTKGRTAYNPALIWKEIKSFLKGSFEALSCPHGRLTEEVYKKLGRKRCPNFKEDRSEIYSLFSLYQQIRSQKGYFDEEDVLYNISRRLSKLRVLPWSIHELYGDEIQDFTQAELALLMKCINDPNSMFLTGDTAQSIMKGVAFRFSDLRSLFHYASRNTIDKQCAVRKPKKIHQLYQNYRSHSGILNLASGVVDLLQFYFPESFDRLPRDSGLFDGPKPTVLESCSVSDLAILLRGNKRKTQPIEFGAHQVILVANETAKEKIPEELGLALVLTIYEAKGLEFDDVLLYNFFTDSEAYKEWKIISSFTPTSTDSREENRPLVEVPLDKPGSSQGRSLMVNPEMYKLLNGELKQLYTAITRARVNLWIFDENREKRAPAFKYFIRRDFVQVVKTDENKDFDDSMFVKTSTPAEWIAQGDYYAKHQCWKVAAKCYQKGGAFEKEKLALAHDTALSMKSKKVSPKEKQLEYLELAKTYLECKEPTLSLKCLSYAKEFQLSAQLCERLGKIRDAAYFYKRSQCYKDAFRCFEQIQEFDLALKMYCQEELFEEAAIAVEKYEEMLKTKTLPISKLSYSASQFYLEAAAKYLSANKMKEMMAVLSKLDIEDQLVFLKSRKRLAEAADLLNREGRREEAALLMKQHGCLLEAARLTADKDFQASCLLGAARLNVARDSDIEHTKDILREALDICYQTGQLSGIAEAHFLQGVILRDFQKLRDAFFKFDTLNHSAGVVEALYEAASQCEAEPEKILGLAPGGLEILLSLVRALKRVTNNAEKEMVKSCFEFFGISQVDAKYCQIAQNDPGPILRIIFDLDLNLREKKTKDHFLIMTDQVKLALNKHLLGRLCQITRSLLGKTYRGVCMRFIVGLKCEDENCEHFHRPLRRCEAKCLVQSKMNLVAINGLLLEAKKVFPKILAEELKEIDYILSTDMYGLCKSILDVLFPKHFHQRVLSENPMACKEILKPNYKSFRFYRFALKEYIHFLFENESARNRRESTDLWLSAMQAFLLSSNYPEEFEKLLHQEEDNYNRELKALESEKDERGRGRGSRIKGIEGKFGMLAPNRDDENMDKTHLCFIRLLENCIDQFYVYRNPEDYKRLFFRFMNVLIKRCKEPLIPSIGNTVALLEFQFIHCGVVLARLWKNVILCLPKSYIALLHYWEFLFSKKDKELGDVFSIIQEYKPKDVTRAIQDFRFHLSYLAKVLCGYENVNFNVLLDAFSEIDYVVSGEAERTLVLCLVMLVNAEEILQPYCKPLLYRHFREIESRLQLMSMDCPGQVPERLLKVVKRVLVAVNVKSVAEALQDLLFERDEEYLMDCDWRWDPVHTKGSIVRGLYYEEVRLNRLLCLDPVDYFAEPECEFGQDEMDELALEDRDHVLATILSQKQRKASIQRKLRRACLVVSLCISWRRRVGTQMERVREEAREPRAGNFKKADVDRTQCDLCGVKFTRGPENYFSPSKAFEGAASEVAVLSRAELEREECQERNSESYEQHIHLEHHQRQQVAYQKYSEFFHEKVDPAIDEGKLVVQDIEQSVWIHSHVGSKEHSHMLQKVQEHIKRVSDMVEDLYRRKAWAGAEEAMTRLVNILILSVRDARDWLMKTETRLKKEGIVQEDDYENEVEDFGELRPRRRSRKCGKQRKY", "length": 2925 }, "evidence": [ { "id": "A0A8V0YQJ5", "url": "https://omabrowser.org/oma/group/A0A8V0YQJ5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8BV79-1", "protein_name": "TPR and ankyrin repeat-containing protein 1", "gene_name": "Trank1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASTTAGRRWPPRRRSSRRGPTPRSRAPGAKLSAPEAGPPRRGPLPRGGAGRDTLLGAKATPSSPAARRYVTALGPPQPRGSTDSACAALPQPVPHEPREAAFRLAPASERGASVSPARIPRRRRRVPAMWDPRAARTPPRELAMLLCNKSNAFYNLGKWNEAFLAAKECLQWDPTYVKGYYRAGYSLLHLLQPYEAARMFFEGLRLLQRSPDQLQVPDFLVGIFTTMSSDSIVLQSFLPCFDHIFTTGFSTEVWQYVIQKLAKKGLWHSFLLLSAKKDRLPSNIHVSELSLQSLFEKYVFIGFYEKLEQVPKLVQWLVSIGANIETIGPNPLHALMRLCIQARESQLFRWVMDQKPEWKEHINHRDDAGCTVLHVAAAHFPGYTSRRQTEDVQMLLSFGADPTLLDGHARTVVDVLKRNKNFRAIDKINSHLEKLASSSKGLSEIPAGLVCDVNRDCATTFIKFLLERQKWPEVLLLLTRKVSGQPQLRNGVIKDCDLSDLDICTVIPHLSSWDQRKTQLLSRLIDSGALPEGLQDSQDRPLLMCLRHEDFDLAFLLLTKGADPRSVSLVEGDTPLHAALHIFLDINADIGFNFLSHLLDLFLSNPTEFYYLNPNVQDSNGNTLMHLLFQKGMLKRTKKLIDLLVKFDINFNLKNKAGKGVRHRIKKNDALLLAWNKALTESRRKNRQDPAAHLGRLSRSSAPGHTSQLKSQTSFKSLPCGTADTTLSKGLTESLPDVQVSRQEPEAVRTRSLRDRLVQDITVLIQQVELGMPLPEDSPQRDSPKVAAGTEGKKDKLQRTQRMGSSGCSGNNPVASEAGDGAQAGPGASQLVPVGNRLGVASDNQENWTMQEIQACLQDFDNMTWEIECTSEMLKKLSSKVMTKVIKKKIILAIQQLGNGEWTQGLQKRLKHSKGNIQLFEAKLDKGARMLWELAIDFSARCSENSEKIIGTERNTYSLEKSGRVYTEIIRIWDIVLDHCKLSDSIMAICSAYTRGLSCVLRKKLKGINKGQVSANMKIQKRIPRCYVEDTEAEKSLEQVDPEYFPPASAVETEYSIMKFHSFSTNMALNILNDMTATVEYPFRVGELEYAVIDLNPKPLEPIILIGRSGTGKTTCCLYRLWKKFHVYWEKAEQAGSPLLSKQILPKRRLEVEPGKEGPGREEEEHEEEEGSIKVETVDGIDEEQESEACAGGATVEPAGDSQGAEGCVPDHPHQLEHLHQIFVTKNHVLCQEVQRNFIELSKSTKATSHYKPLDPNVHKLQDLRDENFPLFVTSKQLLLLLDASLPKPFFLRNEDGSLKRTIVGWSTQEEFSIPSWEEDDEEVEADGNYNEEEKATETQTGDSDPRVYVTFEVFTNEIWPKMIKGRSSYNPALIWKEIKSFLKGSFEALSCPHGRLTEEAYKKLGRKRSPNFKEDRSEIYSLFCLYQQIRSQKGYFDEEDVLYNLSWRLSKLRVLPWSIHELYGDEIQDFTQAELALLMKCINDPNAMFLTGDTAQSIMKGVAFRFSDLLSLFHYASRSTVDKQCAVRKPKRIHQLYQNYRSHSGILNLASGVVDLLQFYFPESFDRLPRDSGLFDGPKPTLLDSCSVSDLAILLRGNKRKTQPIEFGAHQVILVANEKAKEKIPEELGLALVLTVYEAKGLEFDDVLLYNFFTDSEAYKEWKIISSFTPSSDSREEKWPLVDVPLERSSPSQARSLMVNPEMYKLLNGELKQLYTAITRARVNLWIFDENLEKRAPAFKYFIRRDFVQVVKTDENKDFDDSMFVKTSTPYEWIIQGDYYAKHQCWKVAAKCYQKGDALEKEKLALAHYTALNMKSKKFSPKEKELQYLELAKTYLECNEPKLSLKCLSYAKEFQLSAQLCERLGKIRDAAYFYKRSQCFQDAFRCFEQIQEFDLALRMYCQEELFEEAAIAVEKYEEMLKNKTFPIPKLSYSASQFYLEAAAKYLSANKSKEMMAVLSKLDVEDQLVFLKSRKCLAEAAELLNREGRREEAALLMKQHGCLLEAARLTANKDFQASCLLGVARFNVARDSDIEHTKVILREALDLCYQTSQLAGIAEAQFLLGIILRDFQKLRDAFIKFDMLNHSAGMVEALYEAASLCESEHQKVLALAPGGLEVLLNLVRALKNVTNNAEKEMVKSCFEFFGIFQVDAKYCQIAQNDPGPILRIILDLDLTLSEKKTKDHFLIVTDQVKLALNKHLLGRLCQITQILLGKAYPGICMRFIVGLKCEDEQCEDFHRPLRRCEAKCMVQSKMHLVAINGLLLEAKKVFPNVLAEDLEEMDYILSPDTYGLCKSFLNLLFPRHFHQRVLSENPMACKDILKPNYKSFRSFRCALKEYIHDLFQKESAHSRRESTDLWLSAMQAFLLSSSYPEDFEKLLRQEEDSYNRELKVLESDREDRGRGRGSRVRGIEGKFGMLVPNREDENVEKSYLCFIRLLESSMDQLYVRRNPGDYKRLFFRFMNVLIKRCKAPLVPSIINTVVLLELQFVHCGVVLTRLWKNAVLCLPKSYIALLHFWEFLYGKKDRESGEVFSIIQEYKPKDVTRAIRDFRFHLSYLVKVLCGYENMNFNVLLDSFSEIDYVISGEAERTLVLCLVMLVNAEEVLQPFCKPLLFRHFREIQTRLQLMSMDWPGQVPKRLLKVVQRVLVAASVKSVAEALQDLLFERDEEYLVDCHWRWDSVHTKGTVVRGLCHEEVRLNRLLCTGPMDQFADSEWDFGEDETHELDELAQEDRDNFLAAILSQKQRKALIQRKLRRVCLVVSLCIRWRRWVQTEHSREDREVRPGNFKRADVDRTQCDLCGVKFTRSPESYFSPGKAFEGTATEAVLISRAELEGRECRERISESYEQHIRLEGHRRQQAAYQKYLDFFHEKVDPIIEEGKVVVQGIEQSVWIRSHLGSKEQSHMLQRKVQEHIRRVSDLVEELYRRKAWAEAEEVMTQQVKILTLSVKNAQEWLKKTELRLKDEGTVQEEEYENEVEDFGELRPRRRAQKCGKQRKH", "length": 2999 }, "evidence": [ { "id": "A0A8V0YQJ5", "url": "https://omabrowser.org/oma/group/A0A8V0YQJ5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQJ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQJ5" } ], "pmid": "" }, { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQJ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQJ5" } ], "pmid": "" }, { "name": "helicase activity", "id": "GO:0004386", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004386", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQJ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQJ5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1012, "end_pos": 1014, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1411, "end_pos": 1413, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1444, "end_pos": 1446, "annotation": "n_glycosylation_sequon" }, { "start_pos": 157, "end_pos": 159, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1617, "end_pos": 1619, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2007, "end_pos": 2009, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2086, "end_pos": 2088, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2183, "end_pos": 2185, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2324, "end_pos": 2326, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2502, "end_pos": 2504, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2570, "end_pos": 2572, "annotation": "n_glycosylation_sequon" }, { "start_pos": 452, "end_pos": 454, "annotation": "n_glycosylation_sequon" }, { "start_pos": 486, "end_pos": 488, "annotation": "n_glycosylation_sequon" }, { "start_pos": 565, "end_pos": 567, "annotation": "n_glycosylation_sequon" }, { "start_pos": 858, "end_pos": 860, "annotation": "n_glycosylation_sequon" }, { "start_pos": 97, "end_pos": 99, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YQJ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQJ5" }, { "id": "PF00580", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00580" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "UvrD-like helicase ATP-binding", "eco_id": "ECO_0000259", "start_pos": 1400, "end_pos": 1499, "start_aa": "Gln", "end_aa": "Met", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 699, 1719 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1012, "end_pos": 1014 }, { "start_pos": 1411, "end_pos": 1413 }, { "start_pos": 1444, "end_pos": 1446 }, { "start_pos": 157, "end_pos": 159 }, { "start_pos": 1617, "end_pos": 1619 }, { "start_pos": 2007, "end_pos": 2009 }, { "start_pos": 2086, "end_pos": 2088 }, { "start_pos": 2183, "end_pos": 2185 }, { "start_pos": 2324, "end_pos": 2326 }, { "start_pos": 2502, "end_pos": 2504 }, { "start_pos": 2570, "end_pos": 2572 }, { "start_pos": 452, "end_pos": 454 }, { "start_pos": 486, "end_pos": 488 }, { "start_pos": 565, "end_pos": 567 }, { "start_pos": 858, "end_pos": 860 }, { "start_pos": 97, "end_pos": 99 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YQK1-1", "uniprot_ac": "A0A8V0YQK1", "uniprot_id": "A0A8V0YQK1_CHICK", "mass": { "chemical_mass": 38437.0, "monoisotopic_mass": 38437.0 }, "refseq": {}, "gene_names": [ { "name": "TMEM271", "type": "recommended", "evidence": [ { "id": "A0A8V0YQK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQK1" } ] } ], "protein_names": [ { "name": "Transmembrane protein 271", "type": "synonym", "evidence": [ { "id": "A0A8V0YQK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQK1/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQK1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQK1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TMEM271", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQK1", "locus": { "chromosome": "Z", "start_pos": 53877285, "end_pos": 53876143, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010014359", "url": "https://www.ensembl.org/id/ENSGALG00010014359" } ] } } ], "crossref": [ { "id": "A0A8V0YQK1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YQK1", "database": "AlphaFoldDB", "categories": [] }, { "id": "100857745", "url": "https://www.ncbi.nlm.nih.gov/gene/100857745", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "gga:100857745", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100857745", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "EVHCGGH", "url": "https://omabrowser.org/oma/group/EVHCGGH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YQK1", "url": "https://www.orthodb.org/?gene=A0A8V0YQK1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YQK1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQK1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQK1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQK1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKWSVRGACAALSSCLLLACALSAAAVGLKCFSLGSELKGEPFRLGTAAGAFYSGLLLAAGLSLLAAALLCCRPPDEAPAAPAPAPAPAPDPGGGGPGPSSGSGSGSGSGSGPGSCPGAGPGPGPGGSEAAAAAPSGPVEKASPGGRQNFLLLGVLVFMLGVLSAFAGAVIDGDTVSLVERKYSHYCLLQPGGAARPRSGPAAPDGSAAALRCQKLRDYQRGLVLSTVFNALECLLGLLNLLLVKNYKASQQRGRRRRRRRAAPAAAAPAGGRRRRRRGGGGRRAPRHSQGSLFSGGEPELSPGDCPFQAVSYINVGVFHVFDEAGVEVHCGGHPSVELPGYSPMDPELNASYPYCYPLPSEQPPAYEEIYPGEPCAHGT", "length": 380, "header": "tr|A0A8V0YQK1-1|A0A8V0YQK1_CHICK Isoform 1 of Transmembrane protein 271 OS=Gallus gallus OX=9031 GN=TMEM271 PE=4 SV=1 CANONICAL=A0A8V0YQK1-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YQK1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQK1/entry#A0A8V0YQK1-1", "sequence": { "sequence": "MKWSVRGACAALSSCLLLACALSAAAVGLKCFSLGSELKGEPFRLGTAAGAFYSGLLLAAGLSLLAAALLCCRPPDEAPAAPAPAPAPAPDPGGGGPGPSSGSGSGSGSGSGPGSCPGAGPGPGPGGSEAAAAAPSGPVEKASPGGRQNFLLLGVLVFMLGVLSAFAGAVIDGDTVSLVERKYSHYCLLQPGGAARPRSGPAAPDGSAAALRCQKLRDYQRGLVLSTVFNALECLLGLLNLLLVKNYKASQQRGRRRRRRRAAPAAAAPAGGRRRRRRGGGGRRAPRHSQGSLFSGGEPELSPGDCPFQAVSYINVGVFHVFDEAGVEVHCGGHPSVELPGYSPMDPELNASYPYCYPLPSEQPPAYEEIYPGEPCAHGT", "length": 380, "header": "tr|A0A8V0YQK1-1|A0A8V0YQK1_CHICK Isoform 1 of Transmembrane protein 271 OS=Gallus gallus OX=9031 GN=TMEM271 PE=4 SV=1 CANONICAL=A0A8V0YQK1-1" }, "locus": { "chromosome": "Z", "start_pos": 53877282, "end_pos": 53876143, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034566.1", "url": "https://www.ensembl.org/id/ENSGALT00010034566.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020298.1", "url": "https://www.ensembl.org/id/ENSGALP00010020298.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:100857745", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100857745", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A1Y7VLQ2-1", "protein_name": "Transmembrane protein 271, retrotransposed", "gene_name": "Tmem271rt", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKWSVRGACAALSSCLLLACALSAAAVGLKCFSLGSELRGEPFRLGAAAGAFYSGLLLAAGLSLLGAALLCCGPREAPLAGSGAGPGPGLRVPASPAGAPEPSPGETRAAAGPSGPVNSQNLLLLGVLVFMLGVLSAFAGAVIDGDTVSLVERKYSHYCLPPRTPAAGPGQGTGSVAPGTNTQRSRSNLDSNTTAKCRQLKDYQRGLVLSTVFNSLECLLGLLSLLLVKNYKSSQARRGRRGRRRASRSLGRQRGGPGLRAQPLASRTRRGRRGKRGRRLQPRPSEASILSPEESDFTTPGDCASFAAHHAVSYINVGVFHAFDEAGVEVCCGGHPSVELPGYAPSDPDLNASYPYCCRPPCEMARPWEPSRAC", "length": 374 }, "evidence": [ { "id": "A0A8V0YQK1", "url": "https://omabrowser.org/oma/group/A0A8V0YQK1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A286YF58-1", "protein_name": "Transmembrane protein 271", "gene_name": "TMEM271", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKWSVRGACAALSSCLLLACALSAAAVGLKCFSLGSELRGEPFRLGAAAGAFYSGLLLAAGLSLLGAALLCCGPRDAPLAGSEPGPGLGVPAAPAGAPEATPGESGAAAGAPGPVSSQNLLLLGVLVFMLGVLSAFAGAVIDGDTVSLVERKYSHYCLPPRAPGSSPGSAPGSTPGSAPGSAPGSAPGSAPGAPRARSTLDSATSAKCRQLKDYQRGLVLSTVFNSLECLLGLLSLLLVKNYKSSQARRGRRGRRRGGRALARPRGGSGLRAQPPASRARRGRRGRRGRRLQQRPSEASILSPEESDLAAPGDCAGFAAHHAVSYINVGVLHALDEAGAEVRCGGHPSVELPGYAPSDPDLNASYPYCCRPPCETPRPWETHRAC", "length": 385 }, "evidence": [ { "id": "A0A8V0YQK1", "url": "https://omabrowser.org/oma/group/A0A8V0YQK1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 350, "end_pos": 352, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 350, "end_pos": 352 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YQK2-1", "uniprot_ac": "A0A8V0YQK2", "uniprot_id": "A0A8V0YQK2_CHICK", "mass": { "chemical_mass": 65082.0, "monoisotopic_mass": 65082.0 }, "refseq": {}, "gene_names": [ { "name": "LPP", "type": "recommended", "evidence": [ { "id": "A0A8V0YQK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQK2" } ] } ], "protein_names": [ { "name": "LIM domain containing preferred translocation partner in lipoma", "type": "synonym", "evidence": [ { "id": "A0A8V0YQK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQK2/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQK2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQK2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LPP", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQK2", "locus": { "chromosome": "9", "start_pos": 14039774, "end_pos": 14324623, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010014984", "url": "https://www.ensembl.org/id/ENSGALG00010014984" } ] } } ], "crossref": [ { "id": "A0A8V0YQK2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YQK2", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd09350", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09350", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd09356", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09356", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd09436", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09436", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001781", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001781", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR24207", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24207", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24207:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24207:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00412", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00412", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YQK2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQK2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQK2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQK2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSHPSWLPPKSTNEPVGHVTARMETTHAFGTPSISVSTQQTPKKFAPVVAPKPKYNPYKQPGGDDFLPPPPPPVDDLGNITSQGAFPPPPPLDDVAFNVQVNPGGKTLEERRSSLDAEIDSLTSILADLESSSPYKPRIQQGSGTSSSAATTPSVSTPVTGHKRMIIPNQPPLTATKKSTAKGPGQPAPIPVTPIGTLKPQPVPASYTTASTPSRPTFNVQVRTAQPSPHYQPPGPQPTHYGSLGPGQPYAAPPARPPGAQQYGSPQPRGPDYGYAPPPARPSEPSYGYAPQQGRYQDPYYGGYGGRNGSEAPYMPQSTWKVEPAYPSSNTVGQAPPGMYQHPGPKKTYITDPVLAPQPLQQKSGYPSSGPTSSTPAFRPEDELEHLTKKMLYDMENPPSDDYFGRCARCGENVVGEGTGCTAMDQVFHVECFTCMMCNNKLRGQPFYAVEKKAYCEPCYINTLEQCSVCAKPIMERILRATGKAYHPHCFTCVMCHRSLDGIPFTVDAGGNIHCIEDFHKKFAPRCSVCKEPIMPAPGQEETVRIVALDRDFHVQCYRCEDCGGLLSEGDNQGCYPLDGHILCKTCNSARIQALTAKASTDL", "length": 603, "header": "tr|A0A8V0YQK2-1|A0A8V0YQK2_CHICK Isoform 1 of LIM domain containing preferred translocation partner in lipoma OS=Gallus gallus OX=9031 GN=LPP PE=3 SV=1 CANONICAL=A0A8V0YQK2-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YQK2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQK2/entry#A0A8V0YQK2-1", "sequence": { "sequence": "MSHPSWLPPKSTNEPVGHVTARMETTHAFGTPSISVSTQQTPKKFAPVVAPKPKYNPYKQPGGDDFLPPPPPPVDDLGNITSQGAFPPPPPLDDVAFNVQVNPGGKTLEERRSSLDAEIDSLTSILADLESSSPYKPRIQQGSGTSSSAATTPSVSTPVTGHKRMIIPNQPPLTATKKSTAKGPGQPAPIPVTPIGTLKPQPVPASYTTASTPSRPTFNVQVRTAQPSPHYQPPGPQPTHYGSLGPGQPYAAPPARPPGAQQYGSPQPRGPDYGYAPPPARPSEPSYGYAPQQGRYQDPYYGGYGGRNGSEAPYMPQSTWKVEPAYPSSNTVGQAPPGMYQHPGPKKTYITDPVLAPQPLQQKSGYPSSGPTSSTPAFRPEDELEHLTKKMLYDMENPPSDDYFGRCARCGENVVGEGTGCTAMDQVFHVECFTCMMCNNKLRGQPFYAVEKKAYCEPCYINTLEQCSVCAKPIMERILRATGKAYHPHCFTCVMCHRSLDGIPFTVDAGGNIHCIEDFHKKFAPRCSVCKEPIMPAPGQEETVRIVALDRDFHVQCYRCEDCGGLLSEGDNQGCYPLDGHILCKTCNSARIQALTAKASTDL", "length": 603, "header": "tr|A0A8V0YQK2-1|A0A8V0YQK2_CHICK Isoform 1 of LIM domain containing preferred translocation partner in lipoma OS=Gallus gallus OX=9031 GN=LPP PE=3 SV=1 CANONICAL=A0A8V0YQK2-1" }, "locus": { "chromosome": "9", "start_pos": 14235476, "end_pos": 14041827, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010036047.1", "url": "https://www.ensembl.org/id/ENSGALT00010036047.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020929.1", "url": "https://www.ensembl.org/id/ENSGALP00010020929.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 372, "start_aa": "Thr", "end_pos": 372, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr372", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 375, "start_aa": "Thr", "end_pos": 375, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr375", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQK2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQK2" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQK2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQK2" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQK2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQK2" } ], "pmid": "" }, { "name": "focal adhesion", "id": "GO:0005925", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005925", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQK2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQK2" } ], "pmid": "" }, { "name": "stress fiber", "id": "GO:0001725", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001725", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQK2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQK2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQK2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQK2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "cell-cell adhesion", "id": "GO:0098609", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098609", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQK2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQK2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 308, "end_pos": 310, "annotation": "n_glycosylation_sequon" }, { "start_pos": 79, "end_pos": 81, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YQK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQK2" }, { "id": "PS50023", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50023" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "LIM zinc-binding", "eco_id": "ECO_0000259", "start_pos": 405, "end_pos": 464, "start_aa": "Gly", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 372, 375 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 308, "end_pos": 310 }, { "start_pos": 79, "end_pos": 81 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YQK9-1", "uniprot_ac": "A0A8V0YQK9", "uniprot_id": "A0A8V0YQK9_CHICK", "mass": { "chemical_mass": 93299.0, "monoisotopic_mass": 93299.0 }, "refseq": {}, "gene_names": [ { "name": "CASS4", "type": "recommended", "evidence": [ { "id": "A0A8V0YQK9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQK9" } ] } ], "protein_names": [ { "name": "Cas scaffolding protein family member 4", "type": "recommended", "evidence": [ { "id": "A0A8V0YQK9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQK9/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Docking protein that plays a role in tyrosine kinase-based signaling related to cell adhesion and cell spreading. Regulates PTK2/FAK1 activity, focal adhesion integrity, and cell spreading.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQK9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQK9#function" }, { "database": "UniProtKB", "id": "ARBA00055892", "url": "https://www.uniprot.org/uniprotkb/ARBA00055892#function" }, { "database": "UniProtKB", "id": "A0A8V0YWZ9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YWZ9#function" }, { "database": "UniProtKB", "id": "A0A8V0YXE2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXE2#function" }, { "database": "UniProtKB", "id": "A0A8V0Z400", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z400#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQK9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQK9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CASS4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQK9", "locus": { "chromosome": "20", "start_pos": 12333085, "end_pos": 12350319, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010016671", "url": "https://www.ensembl.org/id/ENSGALG00010016671" } ] } } ], "crossref": [ { "id": "A0A8V0YQK9", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YQK9", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd11551", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11551", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd11568", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11568", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd12000", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12000", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "419330", "url": "https://www.ncbi.nlm.nih.gov/gene/419330", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014928", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014928", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR021901", "url": "https://www.ebi.ac.uk/interpro/entry/IPR021901", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035744", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035744", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036028", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036028", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037362", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037362", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038319", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038319", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YQK9", "url": "https://www.orthodb.org/?gene=A0A8V0YQK9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YWZ9", "url": "https://www.orthodb.org/?gene=A0A8V0YWZ9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YXE2", "url": "https://www.orthodb.org/?gene=A0A8V0YXE2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z400", "url": "https://www.orthodb.org/?gene=A0A8V0Z400", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10654", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10654", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10654:SF19", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10654:SF19", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF08824", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08824", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12026", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12026", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14604", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14604", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YQK9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQK9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQK9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQK9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YWZ9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YWZ9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YWZ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YWZ9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YXE2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXE2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YXE2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXE2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z400", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z400", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z400-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z400-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKVNVSCDLSTLFFAGFLYVCIYFKKRENALAKALYDNKAECSDELAFRRGDILTVLEQHVVGSEGWWRCSLHGRQGLAPANRLQLLAGPQALPPPTIPSDAPEPPVAPQNIYQVPSVPKGTASSSTYEKMEGWVTSPARAATLPAQGVYQVPALAAQLLSERTRCSTQQHLFTLPRACRASVPNITSELYDVPSMQSRESLLTQSGATPPAARKGSVLLRSPRCFQEEQQFYNVPSSSEKAGAVIQDSAVGNLYDVPPKRETDASKKKSQKKYWGHCNTLPNPRKSEWIYDIPISPEKTGLKQNSSVHSTENQVLYDIPPARYKALTTNAEANVVNPQLYDIPPTQRKLTFPDVPLYDVPSSKDVLLQQNGSCDVPPSLPAPNAENQISGGNVYDIPKGLPTAMQPKKEMEKNSNHSGNQAYHIPAQLSRDTKPEHDRLPMCGHDNSADSKNSTISMSSNSSSESSSASSSEEPDKEIKLDLEVAIETLTRLQHSVSSSVASLMIFVSSKWRLQEHLEKNIEEIHRAIDHIKVSLGEFLAFARALKVNASYLTDNNLQIRIKKQLEILMNSFQILTETREALNNCNWSLEALVLKKPYSNPDDLDRFVMVARTIPDDLKRFVSIIIANGKLLFRKNEKEQEMKQPRVSPGYKMPKQITSPRRIEIDSLPVSAPDKPNPSQGSNETTKENVSEDCEYVQLQVLPSTKKNAVRSQQDSAKKVVIPEQCRLCFGALHKAIAVFNNSLSSKQPPEVFISHSKLIIMVGQKIVDSLCQDTQLREARSDVLHSSSRFCSLLKNLALATKNAAIQYPNADAMRELQNKNDELYKYTQQFRAMLE", "length": 838, "header": "tr|A0A8V0YQK9-1|A0A8V0YQK9_CHICK Isoform 1 of Cas scaffolding protein family member 4 OS=Gallus gallus OX=9031 GN=CASS4 PE=3 SV=1 CANONICAL=A0A8V0YQK9-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YQK9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQK9/entry#A0A8V0YQK9-1", "sequence": { "sequence": "MKVNVSCDLSTLFFAGFLYVCIYFKKRENALAKALYDNKAECSDELAFRRGDILTVLEQHVVGSEGWWRCSLHGRQGLAPANRLQLLAGPQALPPPTIPSDAPEPPVAPQNIYQVPSVPKGTASSSTYEKMEGWVTSPARAATLPAQGVYQVPALAAQLLSERTRCSTQQHLFTLPRACRASVPNITSELYDVPSMQSRESLLTQSGATPPAARKGSVLLRSPRCFQEEQQFYNVPSSSEKAGAVIQDSAVGNLYDVPPKRETDASKKKSQKKYWGHCNTLPNPRKSEWIYDIPISPEKTGLKQNSSVHSTENQVLYDIPPARYKALTTNAEANVVNPQLYDIPPTQRKLTFPDVPLYDVPSSKDVLLQQNGSCDVPPSLPAPNAENQISGGNVYDIPKGLPTAMQPKKEMEKNSNHSGNQAYHIPAQLSRDTKPEHDRLPMCGHDNSADSKNSTISMSSNSSSESSSASSSEEPDKEIKLDLEVAIETLTRLQHSVSSSVASLMIFVSSKWRLQEHLEKNIEEIHRAIDHIKVSLGEFLAFARALKVNASYLTDNNLQIRIKKQLEILMNSFQILTETREALNNCNWSLEALVLKKPYSNPDDLDRFVMVARTIPDDLKRFVSIIIANGKLLFRKNEKEQEMKQPRVSPGYKMPKQITSPRRIEIDSLPVSAPDKPNPSQGSNETTKENVSEDCEYVQLQVLPSTKKNAVRSQQDSAKKVVIPEQCRLCFGALHKAIAVFNNSLSSKQPPEVFISHSKLIIMVGQKIVDSLCQDTQLREARSDVLHSSSRFCSLLKNLALATKNAAIQYPNADAMRELQNKNDELYKYTQQFRAMLE", "length": 838, "header": "tr|A0A8V0YQK9-1|A0A8V0YQK9_CHICK Isoform 1 of Cas scaffolding protein family member 4 OS=Gallus gallus OX=9031 GN=CASS4 PE=3 SV=1 CANONICAL=A0A8V0YQK9-1" }, "locus": { "chromosome": "20", "start_pos": 12347829, "end_pos": 12334293, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010040192.1", "url": "https://www.ensembl.org/id/ENSGALT00010040192.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023300.1", "url": "https://www.ensembl.org/id/ENSGALP00010023300.1" } ] } }, { "isoform_ac": "A0A8V0YWZ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQK9/entry#A0A8V0YWZ9-1", "sequence": { "sequence": "MLNALAKALYDNKAECSDELAFRRGDILTVLEQHVVGSEGWWRCSLHGRQGLAPANRLQLLAGPQALPPPTIPSDAPEPPVAPQNIYQVPSVPKGTASSSTYEKMEGWVTSPARAATLPAQGVYQVPALAAQLLSERTRCSTQQHLFTLPRACRASVPNITSELYDVPSMQSRESLLTQSGATPPAARKGSVLLRSPRCFQEEQQFYNVPSSSEKAGAVIQDSAVGNLYDVPPKRETDASKKKSQKKYWGHCNTLPNPRKSEWIYDIPISPEKTGLKQNSSVHSTENQVLYDIPPARYKALTTNAEANVVNPQLYDIPPTQRKLTFPDVPLYDVPSSKDVLLQQNGSCDVPPSLPAPNAENQISGGNVYDIPKGLPTAMQPKKEMEKNSNHSGNQAYHIPAQLSRDTKPEHDRLPMCGHDNSADSKNSTISMSSNSSSESSSASSSEEPDKEIKLDLEVAIETLTRLQHSVSSSVASLMIFVSSKWRLQEHLEKNIEEIHRAIDHIKVSLGEFLAFARALKVNASYLTDNNLQIRIKKQLEILMNSFQILTETREALNNCNWSLEALVLKKPYSNPDDLDRFVMVARTIPDDLKRFVSIIIANGKLLFRKNEKEQEMKQPRVSPGYKMPKQITSPRRIEIDSLPVSAPDKPNPSQGSNETTKENVSEDCEYVQLQVLPSTKKNAVRSQQDSAKKVVIPEQCRLCFGALHKAIAVFNNSLSSKQPPEVFISHSKLIIMVGQKIVDSLCQDTQLREARSDVLHSSSRFCSLLKNLALATKNAAIQYPNADAMRELQNKNDELYKYTQQFRAMLE", "length": 812, "header": "tr|A0A8V0YWZ9-1|A0A8V0YWZ9_CHICK Computationally mapped isoform of Cas scaffolding protein family member 4 OS=Gallus gallus OX=9031 GN=CASS4 PE=3 SV=1 CANONICAL=A0A8V0YQK9-1" }, "locus": { "chromosome": "20", "start_pos": 12350252, "end_pos": 12334293, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010040199.1", "url": "https://www.ensembl.org/id/ENSGALT00010040199.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023307.1", "url": "https://www.ensembl.org/id/ENSGALP00010023307.1" } ] } }, { "isoform_ac": "A0A8V0YXE2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQK9/entry#A0A8V0YXE2-1", "sequence": { "sequence": "MRSSRTAKNALAKALYDNKAECSDELAFRRGDILTVLEQHVVGSEGWWRCSLHGRQGLAPANRLQLLAGPQALPPPTIPSDAPEPPVAPQNIYQVPSVPKGTASSSTYEKMEGWVTSPARAATLPAQGVYQVPALAAQLLSERTRCSTQQHLFTLPRACRASVPNITSELYDVPSMQSRESLLTQSGATPPAARKGSVLLRSPRCFQEEQQFYNVPSSSEKAGAVIQDSAVGNLYDVPPKRETDASKKKSQKKYWGHCNTLPNPRKSEWIYDIPISPEKTGLKQNSSVHSTENQVLYDIPPARYKALTTNAEANVVNPQLYDIPPTQRKLTFPDVPLYDVPSSKDVLLQQNGSCDVPPSLPAPNAENQISGGNVYDIPKGLPTAMQPKKEMEKNSNHSGNQAYHIPAQLSRDTKPEHDRLPMCGHDNSADSKNSTISMSSNSSSESSSASSSEEPDKEIKLDLEVAIETLTRLQHSVSSSVASLMIFVSSKWRLQEHLEKNIEEIHRAIDHIKVSLGEFLAFARALKVNASYLTDNNLQIRIKKQLEILMNSFQILTETREALNNCNWSLEALVLKKPYSNPDDLDRFVMVARTIPDDLKRFVSIIIANGKLLFRKNEKEQEMKQPRVSPGYKMPKQITSPRRIEIDSLPVSAPDKPNPSQGSNETTKENVSEDCEYVQLQAQKIISGKEVSEKSTDSKPKVLPSTKKNAVRSQQDSAKKVVIPEQCRLCFGALHKAIAVFNNSLSSKQPPEVFISHSKLIIMVGQKIVDSLCQDTQLREARSDVLHSSSRFCSLLKNLALATKNAAIQYPNADAMRELQNKNDELYKYTQQFRAMLE", "length": 838, "header": "tr|A0A8V0YXE2-1|A0A8V0YXE2_CHICK Computationally mapped isoform of Cas scaffolding protein family member 4 OS=Gallus gallus OX=9031 GN=CASS4 PE=3 SV=1 CANONICAL=A0A8V0YQK9-1" }, "locus": { "chromosome": "20", "start_pos": 12350034, "end_pos": 12334293, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010040196.1", "url": "https://www.ensembl.org/id/ENSGALT00010040196.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023304.1", "url": "https://www.ensembl.org/id/ENSGALP00010023304.1" } ] } }, { "isoform_ac": "A0A8V0Z400-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQK9/entry#A0A8V0Z400-1", "sequence": { "sequence": "MKVNNALAKALYDNKAECSDELAFRRGDILTVLEQHVVGSEGWWRCSLHGRQGLAPANRLQLLAGPQALPPPTIPSDAPEPPVAPQNIYQVPSVPKGTASSSTYEKMEGWVTSPARAATLPAQGVYQVPALAAQLLSERTRCSTQQHLFTLPRACRASVPNITSELYDVPSMQSRESLLTQSGATPPAARKGSVLLRSPRCFQEEQQFYNVPSSSEKAGAVIQDSAVGNLYDVPPKRETDASKKKSQKKYWGHCNTLPNPRKSEWIYDIPISPEKTGLKQNSSVHSTENQVLYDIPPARYKALTTNAEANVVNPQLYDIPPTQRKLTFPDVPLYDVPSSKDVLLQQNGSCDVPPSLPAPNAENQISGGNVYDIPKGLPTAMQPKKEMEKNSNHSGNQAYHIPAQLSRDTKPEHDRLPMCGHDNSADSKNSTISMSSNSSSESSSASSSEEPDKEIKLDLEVAIETLTRLQHSVSSSVASLMIFVSSKWRLQEHLEKNIEEIHRAIDHIKVSLGEFLAFARALKVNASYLTDNNLQIRIKKQLEILMNSFQILTETREALNNCNWSLEALVLKKPYSNPDDLDRFVMVARTIPDDLKRFVSIIIANGKLLFRKNEKEQEMKQPRVSPGYKMPKQITSPRRIEIDSLPVSAPDKPNPSQGSNETTKENVSEDCEYVQLQAQKIISGKEVSEKSTDSKPKVLPSTKKNAVRSQQDSAKKVVIPEQCRLCFGALHKAIAVFNNSLSSKQPPEVFISHSKLIIMVGQKIVDSLCQDTQLREARSDVLHSSSRFCSLLKNLALATKNAAIQYPNADAMRELQNKNDELYKYTQQFRAMLE", "length": 834, "header": "tr|A0A8V0Z400-1|A0A8V0Z400_CHICK Computationally mapped isoform of Cas scaffolding protein family member 4 OS=Gallus gallus OX=9031 GN=CASS4 PE=3 SV=1 CANONICAL=A0A8V0YQK9-1" }, "locus": { "chromosome": "20", "start_pos": 12347829, "end_pos": 12334293, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010040193.1", "url": "https://www.ensembl.org/id/ENSGALT00010040193.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023301.1", "url": "https://www.ensembl.org/id/ENSGALP00010023301.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQK9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQK9" } ], "pmid": "" }, { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": 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This record is derived from a genomic sequence (NC_052535.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004940952", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004940952" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQQ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQQ0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RBM46", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQQ0", "locus": { "chromosome": "4", "start_pos": 19893568, "end_pos": 19884544, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010015021", "url": "https://www.ensembl.org/id/ENSGALG00010015021" } ] } } ], "crossref": [ { "id": "A0A8V0YQQ0", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YQQ0", "database": 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{ "isoform_ac": "A0A8V0YQQ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQQ0/entry#A0A8V0YQQ0-1", "sequence": { "sequence": "MNEENSAATSESDKMRGGNQKAAALLALLDKTGYNMIQENGQRKFGGPPPGWEGPPPPRGCEVFVGKIPRNIYEDELVPLFERAGKIYELRLMMEFSGENRGFAFVMYTTKEDAQLAIKILNNYEIRPGRFIGVCISLDNCRLFIGAIPREKKKEEILKEMKRITEGVVDVIVCPDATDRTKNRGFAFVEYESHRAAAMARRRLLPGTFQLWGRAVQVDWACPEKEVDAETMRRVKVLYVRNLMISTTEDTIKAEFNKFKPRVVERVKKLRDYAFVHFYNREDAVAAMSIMNGKCIDGASIEVTLAKPVNKESTWKQHLNGHVSPCSENLMEFRSREDGHQKSVGKPASLSLSLNGQHSPSSPELEWYPYPFLPGVKLIPISMYSLKSSYFSSAVMRLDYFCYKNNWLPPEYYLYSTTSQDGKIHLVCKVLIPSIADGSQSCFMSHKLCTTLEDARELAARMALLHLDSCTPNSA", "length": 475, "header": "tr|A0A8V0YQQ0-1|A0A8V0YQQ0_CHICK Isoform 1 of Probable RNA-binding protein 46 OS=Gallus gallus OX=9031 GN=RBM46 PE=4 SV=1 CANONICAL=A0A8V0YQQ0-1" }, "locus": { "chromosome": "4", "start_pos": 19892353, "end_pos": 19886198, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010036113.1", "url": "https://www.ensembl.org/id/ENSGALT00010036113.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020975.1", "url": "https://www.ensembl.org/id/ENSGALP00010020975.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:422404", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422404", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6ACM5-1", "protein_name": "Probable RNA-binding protein 46", "gene_name": "Rbm46", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MNEENTDGTNGCSKVRTGTQNEAALLALMEKTGYNMVQENGQRKFGGPPPGWEGPPPPRGCEVFVGKIPRDMYEDELVPVFERAGKIYEFRLMMEFSGENRGYAFVMYTTKEEAQLAIRILNNYEIRPGKFIGVCVSLDNCRLFIGAIPKEKKKEEILDEMKKVTEGVVDVIVYPSATDKTKNRGFAFVEYESHRAAAMARRKLIPGTFQLWGHTIQVDWADPEKEVDEETMQRVKVLYVRNLMISTTEETIKAEFNKFKPGAVERVKKLRDYAFVHFFNREDAVAAMSVMNGKCIDGASIEVTLAKPVNKENTWRQHLNGQISPNSENLLVYANKEESHSKSLGKPPTLPTRLNGQHSPSPPEIERCTYPFFPGTKLTPISMYSLKSNHFNSAVMHLDYYCNKNNWAPPEYYLYSTTSQDGKVLLVYKIVIPAIANGSQSYFMPDKLCTTLEDAKELAAQFTLLHLDYNFRRSSINSLSPVSATLSTGTPSVLPYTSRPYSYPSYPLSPTISLANGSHVGQRLYISNQASFF", "length": 533 }, "evidence": [ { "id": "A0A8V0YQQ0", "url": "https://omabrowser.org/oma/group/A0A8V0YQQ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E1BB24-1", "protein_name": "Probable RNA-binding protein 46", "gene_name": "RBM46", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSEETIDGTNGCSKVRTGTQNEAALLALMEKTGYNMVQENGQRKFGGPPPGWEGPPPPRGCEVFVGKIPRDMYEDELVPVFERAGKIYEFRLMMEFSGENRGYAFVMYTTKEEAQLAIRILNNYEIRPGKFIGVCVSLDNCRLFIGAIPKEKKKEEILDEMKKVTEGVVDVIVYPSATDKTKNRGFAFVEYESHRAAAMARRKLIPGTFQLWGHTIQVDWADPEKEVDEETMQRVKVLYVRNLMISTTEETIKAEFNKFKPGSVERVKKLRDYAFVHFFNREDAVAAMSVMNGKCIDGASIEVTLAKPVNKENTWRQHLNGQISPNSENLIVFANKEESHPKILGKPPALPARLNGQHSPSPPEIERCTYPFFPGTKLTPISMYSLKSNHFNSAVMHLDYYCNKNNWAPPEYYLYSTTSQDGKVLLVYKIIIPAIANGSQSYFMPDKLCTTLEDAKELAAQFTLLHLDYNFRRSSINSLSPVSATLSSGTPSVLPYTSRPYSYSSYSLSPTIPLANGSHVGQRLYISNQASFF", "length": 533 }, "evidence": [ { "id": "A0A8V0YQQ0", "url": "https://omabrowser.org/oma/group/A0A8V0YQQ0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P86049-1", "protein_name": "Probable RNA-binding protein 46", "gene_name": "Rbm46", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNEENTDGTNGCSKVRTGTQNEAALLALMEKTGYNMVQENGQRKFGGPPPGWEGPPPPRGCEVFVGKIPRDMYEDELVPVFERAGKIYEFRLMMEFSGENRGYAFVMYTTKEEAQLAIRILNNYEIRPGKFIGVCVSLDNCRLFIGAIPKEKKKEEILDEMKKVTEGVVDVIVYPSATDKTKNRGFAFVEYESHRAAAMARRKLIPGTFQLWGHTIQVDWADPEKEVDEETMQRVKVLYVRNLMISTTEETIKAEFSKFKPGAVERVKKLRDYAFVHFFHREDAVAAMSVMNGKCIDGASIEVTLAKPVNKENTWRQHLNGQISPNSENLLVYANKEESHSKSLGKPPTLPTRLNGQHSPSPPEIERCTYPFFPGTKLTPISMYSLKSNHFNSAVMHLDYYCNKNNWAPPEYYLYSTTSQDGKVLLVYKIVIPAIANGSQSYFMPDKLCTTLEDAKELAAQFTLLHLDFNFRRSSINSLSPVSTTLSSGTPSMLPYTSRPSSYPSYPLSPTISLANGSHVGQRLYISNQASFF", "length": 533 }, "evidence": [ { "id": "A0A8V0YQQ0", "url": "https://omabrowser.org/oma/group/A0A8V0YQQ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8TBY0-1", "protein_name": "Probable RNA-binding protein 46", "gene_name": "RBM46", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNEENIDGTNGCSKVRTGIQNEAALLALMEKTGYNMVQENGQRKFGGPPPGWEGPPPPRGCEVFVGKIPRDMYEDELVPVFERAGKIYEFRLMMEFSGENRGYAFVMYTTKEEAQLAIRILNNYEIRPGKFIGVCVSLDNCRLFIGAIPKEKKKEEILDEMKKVTEGVVDVIVYPSATDKTKNRGFAFVEYESHRAAAMARRKLIPGTFQLWGHTIQVDWADPEKEVDEETMQRVKVLYVRNLMISTTEETIKAEFNKFKPGAVERVKKLRDYAFVHFFNREDAVAAMSVMNGKCIDGASIEVTLAKPVNKENTWRQHLNGQISPNSENLIVFANKEESHPKTLGKLPTLPARLNGQHSPSPPEVERCTYPFYPGTKLTPISMYSLKSNHFNSAVMHLDYYCNKNNWAPPEYYLYSTTSQDGKVLLVYKIVIPAIANGSQSYFMPDKLCTTLEDAKELAAQFTLLHLDYNFHRSSINSLSPVSATLSSGTPSVLPYTSRPYSYPGYPLSPTISLANGSHVGQRLCISNQASFF", "length": 533 }, "evidence": [ { "id": "A0A8V0YQQ0", "url": "https://omabrowser.org/oma/group/A0A8V0YQQ0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQQ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQQ0" } ], "pmid": "" }, { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQQ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQQ0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQQ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQQ0" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQQ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQQ0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "female meiotic nuclear division", "id": "GO:0007143", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007143", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQQ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQQ0" } ], "pmid": "" }, { "name": "male meiotic nuclear division", "id": "GO:0007140", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007140", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQQ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQQ0" } ], "pmid": "" }, { "name": "oogenesis", "id": "GO:0048477", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048477", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQQ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQQ0" } ], "pmid": "" }, { "name": "spermatid differentiation", "id": "GO:0048515", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048515", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQQ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQQ0" } ], "pmid": "" }, { "name": "cell cycle switching, mitotic to meiotic cell cycle", "id": "GO:0051728", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051728", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQQ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQQ0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YQQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQQ0" }, { "id": "PS50102", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50102" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RRM", "eco_id": "ECO_0000259", "start_pos": 61, "end_pos": 139, "start_aa": "Cys", "end_aa": "Asp", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YQR1-1", "uniprot_ac": "A0A8V0YQR1", "uniprot_id": "A0A8V0YQR1_CHICK", "mass": { "chemical_mass": 78286.0, "monoisotopic_mass": 78286.0 }, "refseq": {}, "gene_names": [ { "name": "TRAF3IP1", "type": "recommended", "evidence": [ { "id": "A0A8V0YQR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQR1" } ] } ], "protein_names": [ { "name": "TRAF3-interacting protein 1", "type": "recommended", "evidence": [ { "id": "A0A8V0YQR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQR1/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQR1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQR1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TRAF3IP1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQR1", "locus": { "chromosome": "7", "start_pos": 6013763, "end_pos": 5976160, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010015025", "url": "https://www.ensembl.org/id/ENSGALG00010015025" } ] } } ], "crossref": [ { "id": "A0A8V0YQR1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YQR1", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR018799", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018799", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040468", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040468", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041476", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041476", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042576", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042576", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YQM4", "url": "https://www.orthodb.org/?gene=A0A8V0YQM4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YQR1", "url": "https://www.orthodb.org/?gene=A0A8V0YQR1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YSD5", "url": "https://www.orthodb.org/?gene=A0A8V0YSD5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31363", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31363", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31363:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31363:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10243", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10243", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17749", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17749", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-5620924", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5620924", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YQM4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQM4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQM4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQM4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQR1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQR1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQR1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQR1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YSD5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSD5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YSD5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSD5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLPAGDGGGGGGAVPAVAMNEAVVRRTQECLGQVIRKPPLTDRLLSKPPFRYLHDVITEVIRVTGFLKGLYTDFELKSDNVKDKDAKISFLQKAIDAVVMVTGEPLSVKPARVVAGHEPEKTNEFLQAIGKCCLNKLSSDVAVKKILAGERADAKGKPPSSKPRDTESRESKTEDQKSRRDKEGRGDTDIKDRSSSRDRKPKGDVKESEEREKESEKQKDNEDRHKDSERDNFKEGEKQERERNKSRTTKQGRETEKSKGKRDIEREDNSEWDKVQEREKKNEGGRETDRLKGRDKDKAREREREKDKEKGKDHERNRQRDRGKDGEHVQEHGKDKTEKKSADSEESKLRKLQRPTKAIKCQPDDESESPAGISRQPSTKGSRQRAKPRGEGTVEMKSVADGISEDNAAKLQEEAEPGLVVKQKEEEAENLDPEKPALSENGEVPNHLPPQAIQRRIPRPGSARPAPPRVVKRQESTEALIPERNGSGKAISNVIVDQQASDDDDDQFVVEAAMPVPEMPELEMEPEVDLVEDEKHGGLVKRILETKKDYEASQRSSKVTEKEKPFVSEAARKKERDLVAKEVEKFRDSIQTLCRSAFTLGRIMDYVQEDMDAMKNELQMWRHENRQHAEALQKEQSITDSAVEPLKAELAELDQLIEDQQDKIRAVKANILKNEDKIRRMVLSINLSSRR", "length": 691, "header": "tr|A0A8V0YQR1-1|A0A8V0YQR1_CHICK Isoform 1 of TRAF3-interacting protein 1 OS=Gallus gallus OX=9031 GN=TRAF3IP1 PE=1 SV=1 CANONICAL=A0A8V0YQR1-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YQM4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQR1/entry#A0A8V0YQM4-1", "sequence": { "sequence": "MNEAVVRRTQECLGQVIRKPPLTDRLLSKPPFRYLHDVITEDKDAKISFLQKAIDAVVMVTGEPLSVKPARVVAGHEPEKTNEFLQAIGKCCLNKLSSDVAVKKILAGERADAKGKPPSSKPRDTESRESKTEDQKSRRDKEGRGDTDIKDRSSSRDRKPKGDVKESEEREKESEKQKDNEDRHKDSERDNFKEGEKQERERNKSRTTKQGRETEKSKGKRDIEREDNSEWDKVQEREKKNEGGRETDRLKGRDKDKAREREREKDKEKGKDHERNRQRDRGKDGEHVQEHGKDKTEKKSESPAGISRQPSTKGSRQRAKPRGEGTVEMKSVADGISEDNAAKLQEEAEPGLVVKQKEEEAENLDPEKPALSENGEVPNHLPPQAIQRRIPRPGSARPAPPRVVKRQESTEALIPERNGSGKAISNVIVDQQASDDDDDQFVVEAAMPVPEMPELEMEPEVDLVEDEKHGGLVKRILETKKDYEASQRSSKVTEKEKPFVSEAARKKERDLVAKEVEKFRDSIQTLCRSAFTLGRIMDYVQEDMDAMKNELQMWRHENRQHAEALQKEQSITDSAVEPLKAELAELDQLIEDQQDKIRAVKANILKNEDKIRRMVLSINLSSRR", "length": 624, "header": "tr|A0A8V0YQM4-1|A0A8V0YQR1_CHICK Computationally mapped isoform of TRAF3-interacting protein 1 OS=Gallus gallus OX=9031 GN=TRAF3IP1 PE=1 SV=1 CANONICAL=A0A8V0YQR1-1" }, "locus": { "chromosome": "7", "start_pos": 6012658, "end_pos": 5976218, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010036124.1", "url": "https://www.ensembl.org/id/ENSGALT00010036124.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020983.1", "url": "https://www.ensembl.org/id/ENSGALP00010020983.1" } ] } }, { "isoform_ac": "A0A8V0YQR1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQR1/entry#A0A8V0YQR1-1", "sequence": { "sequence": "MLPAGDGGGGGGAVPAVAMNEAVVRRTQECLGQVIRKPPLTDRLLSKPPFRYLHDVITEVIRVTGFLKGLYTDFELKSDNVKDKDAKISFLQKAIDAVVMVTGEPLSVKPARVVAGHEPEKTNEFLQAIGKCCLNKLSSDVAVKKILAGERADAKGKPPSSKPRDTESRESKTEDQKSRRDKEGRGDTDIKDRSSSRDRKPKGDVKESEEREKESEKQKDNEDRHKDSERDNFKEGEKQERERNKSRTTKQGRETEKSKGKRDIEREDNSEWDKVQEREKKNEGGRETDRLKGRDKDKAREREREKDKEKGKDHERNRQRDRGKDGEHVQEHGKDKTEKKSADSEESKLRKLQRPTKAIKCQPDDESESPAGISRQPSTKGSRQRAKPRGEGTVEMKSVADGISEDNAAKLQEEAEPGLVVKQKEEEAENLDPEKPALSENGEVPNHLPPQAIQRRIPRPGSARPAPPRVVKRQESTEALIPERNGSGKAISNVIVDQQASDDDDDQFVVEAAMPVPEMPELEMEPEVDLVEDEKHGGLVKRILETKKDYEASQRSSKVTEKEKPFVSEAARKKERDLVAKEVEKFRDSIQTLCRSAFTLGRIMDYVQEDMDAMKNELQMWRHENRQHAEALQKEQSITDSAVEPLKAELAELDQLIEDQQDKIRAVKANILKNEDKIRRMVLSINLSSRR", "length": 691, "header": "tr|A0A8V0YQR1-1|A0A8V0YQR1_CHICK Isoform 1 of TRAF3-interacting protein 1 OS=Gallus gallus OX=9031 GN=TRAF3IP1 PE=1 SV=1 CANONICAL=A0A8V0YQR1-1" }, "locus": { "chromosome": "7", "start_pos": 6012658, "end_pos": 5976164, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010036126.1", "url": "https://www.ensembl.org/id/ENSGALT00010036126.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020985.1", "url": "https://www.ensembl.org/id/ENSGALP00010020985.1" } ] } }, { "isoform_ac": "A0A8V0YSD5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQR1/entry#A0A8V0YSD5-1", "sequence": { "sequence": "MLPAGDGGGGGGAVPAVAMNEAVVRRTQECLGQVIRKPPLTDRLLSKPPFRYLHDVITEVIRVTGFLKGLYTDFELKSDNVKDKDAKISFLQKAIDAVVMVTGEPLSVKPARVVAGHEPEKTNEFLQAIGKCCLNKLSSDVAVKKILAGERADAKGKPPSSKPRDTESRESKTEDQKSRRDKEGRGDTDIKDRSSSRDRKPKGDVKESEEREKESEKQKDNEDRHKDSERDNFKEGEKQERERNKSRTTKQGRETEKSKGKRDIEREDNSEWDKVQEREKKNEGGRETDRLKGRDKDKAREREREKDKEKGKDHERNRQRDRGKDGEHVQEHGKDKTEKKSESPAGISRQPSTKGSRQRAKPRGEGTVEMKSVADGISEDNAAKLQEEAEPGLVVKQKEEEAENLDPEKPALSENGEVPNHLPPQAIQRRIPRPGSARPAPPRVVKRQESTEALIPERNGSGKAISNVIVDQQASDDDDDQFVVEAAMPVPEMPELEMEPEVDLVEDEKHGGLVKRILETKKDYEASQRSSKVTEKEKPFVSEAARKKERDLVAKEVEKFRDSIQTLCRSAFTLGRIMDYVQEDMDAMKNELQMWRHENRQHAEALQKEQSITDSAVEPLKAELAELDQLIEDQQDKIRAVKANILKNEDKIRRMVLSINLSSRR", "length": 665, "header": "tr|A0A8V0YSD5-1|A0A8V0YSD5_CHICK Computationally mapped isoform of TRAF3-interacting protein 1 OS=Gallus gallus OX=9031 GN=TRAF3IP1 PE=1 SV=1 CANONICAL=A0A8V0YQR1-1" }, "locus": { "chromosome": "7", "start_pos": 6012658, "end_pos": 5976164, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010036130.1", "url": "https://www.ensembl.org/id/ENSGALT00010036130.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020989.1", "url": "https://www.ensembl.org/id/ENSGALP00010020989.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-5620924", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5620924", "resource": "Reactome", "description": "Intraflagellar transport" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "microtubule binding", "id": "GO:0008017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008017", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQR1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQR1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 8, "go_terms": [ { "name": "axoneme", "id": "GO:0005930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005930", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQR1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQR1" } ], "pmid": "" }, { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQR1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQR1" } ], "pmid": "" }, { "name": "ciliary basal body", "id": "GO:0036064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036064", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQR1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQR1" } ], "pmid": "" }, { "name": "ciliary base", "id": "GO:0097546", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097546", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQR1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQR1" } ], "pmid": "" }, { "name": "intraciliary transport particle A", "id": "GO:0030991", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030991", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQR1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQR1" } ], "pmid": "" }, { "name": "ciliary transition zone", "id": "GO:0035869", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035869", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQR1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQR1" } ], "pmid": "" }, { "name": "intraciliary transport particle B", "id": "GO:0030992", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030992", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQR1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQR1" } ], "pmid": "" }, { "name": "ciliary tip", "id": "GO:0097542", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097542", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQR1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQR1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 11, "go_terms": [ { "name": "cell projection organization", "id": "GO:0030030", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030030", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQR1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQR1" } ], "pmid": "" }, { "name": "kidney development", "id": "GO:0001822", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001822", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQR1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQR1" } ], "pmid": "" }, { "name": "cilium assembly", "id": "GO:0060271", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060271", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQR1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQR1" } ], "pmid": "" }, { "name": "negative regulation of protein-containing complex assembly", "id": "GO:0031333", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031333", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQR1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQR1" } ], "pmid": "" }, { "name": "morphogenesis of a polarized epithelium", "id": "GO:0001738", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001738", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQR1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQR1" } ], "pmid": "" }, { "name": "intraciliary transport", "id": "GO:0042073", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042073", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQR1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQR1" } ], "pmid": "" }, { "name": "regulation of microtubule cytoskeleton organization", "id": "GO:0070507", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070507", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQR1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQR1" } ], "pmid": "" }, { "name": "negative regulation of defense response to virus", "id": "GO:0050687", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050687", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQR1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQR1" } ], "pmid": "" }, { "name": "negative regulation of type I interferon production", "id": "GO:0032480", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032480", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQR1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQR1" } ], "pmid": "" }, { "name": "system development", "id": "GO:0048731", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048731", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQR1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQR1" } ], "pmid": "" }, { "name": "animal organ development", "id": "GO:0048513", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048513", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQR1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQR1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 244, "end_pos": 246, "annotation": "n_glycosylation_sequon" }, { "start_pos": 485, "end_pos": 487, "annotation": "n_glycosylation_sequon" }, { "start_pos": 686, "end_pos": 688, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YQR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQR1" }, { "id": "PF17749", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17749" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "TRAF3-interacting protein 1 C-terminal", "eco_id": "ECO_0000259", "start_pos": 532, "end_pos": 685, "start_aa": "Glu", "end_aa": "Ile", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0YQR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQR1" }, { "id": "PF10243", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10243" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "TRAF3-interacting protein 1 N-terminal", "eco_id": "ECO_0000259", "start_pos": 23, "end_pos": 134, "start_aa": "Val", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 244, "end_pos": 246 }, { "start_pos": 485, "end_pos": 487 }, { "start_pos": 686, "end_pos": 688 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YQP2-1", "uniprot_ac": "A0A8V0YQP2", "uniprot_id": "A0A8V0YQP2_CHICK", "mass": { "chemical_mass": 23850.0, "monoisotopic_mass": 23850.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "SH3 domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A8V0YQP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQP2/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQP2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQP2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQP2", "locus": {} } ], "crossref": [ { "id": "A0A8V0YQP2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YQP2", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR001452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036028", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036028", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040325", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040325", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR14234", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14234", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14234:SF20", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14234:SF20", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07653", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07653", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YQP2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQP2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQP2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQP2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "ASPYPTRESELPLTTGQHLNVFGAVDENGWFQGELTDGTRGLVPSNLVMEPGGGCPAGERGTRALGKVRGILLCSASTDKAQTPGHSPSPRPRGSHGQCLCGLSLPNERWKQSFLSSATFQRFLARHSYNPVEGPNEEPESELPLTAGQHLNVFGAVDENVWFQGELTDGTRGLVPSSLVAECNCIVLWYIKQTNKQTPPTIKQPTNQPKKRCSFSWIH", "length": 219, "header": "tr|A0A8V0YQP2-1|A0A8V0YQP2_CHICK Isoform 1 of SH3 domain-containing protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0YQP2-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YQP2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQP2/entry#A0A8V0YQP2-1", "sequence": { "sequence": "ASPYPTRESELPLTTGQHLNVFGAVDENGWFQGELTDGTRGLVPSNLVMEPGGGCPAGERGTRALGKVRGILLCSASTDKAQTPGHSPSPRPRGSHGQCLCGLSLPNERWKQSFLSSATFQRFLARHSYNPVEGPNEEPESELPLTAGQHLNVFGAVDENVWFQGELTDGTRGLVPSSLVAECNCIVLWYIKQTNKQTPPTIKQPTNQPKKRCSFSWIH", "length": 219, "header": "tr|A0A8V0YQP2-1|A0A8V0YQP2_CHICK Isoform 1 of SH3 domain-containing protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0YQP2-1" }, "locus": { "chromosome": "23", "start_pos": 224216, "end_pos": 202144, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010040240.1", "url": "https://www.ensembl.org/id/ENSGALT00010040240.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023331.1", "url": "https://www.ensembl.org/id/ENSGALP00010023331.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YQP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQP2" }, { "id": "PS50002", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50002" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SH3", "eco_id": "ECO_0000259", "start_pos": 1, "end_pos": 53, "start_aa": "Ala", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YQP5-1", "uniprot_ac": "A0A8V0YQP5", "uniprot_id": "A0A8V0YQP5_CHICK", "mass": { "chemical_mass": 25232.0, "monoisotopic_mass": 25232.0 }, "refseq": { "ac": "XP_046759533", "name": "UPF0500 protein C1orf216 homolog", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046759533" }, "gene_names": [ { "name": "C1orf216", "type": "recommended", "evidence": [ { "id": "A0A8V0YQP5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQP5" } ] }, { "name": "C1orf216", "type": "synonym", "evidence": [ { "id": "XP_046759533", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046759533" } ] } ], "protein_names": [ { "name": "Chromosome 1 open reading frame 216", "type": "synonym", "evidence": [ { "id": "A0A8V0YQP5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQP5/entry#names_and_taxonomy" } ] }, { "name": "UPF0500 protein C1orf216 homolog", "type": "synonym", "evidence": [ { "id": "XP_046759533", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046759533" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052554.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_046759533", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046759533" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQP5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQP5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "C1orf216", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQP5", "locus": { "chromosome": "23", "start_pos": 4611035, "end_pos": 4608548, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010015032", "url": "https://www.ensembl.org/id/ENSGALG00010015032" } ] } } ], "crossref": [ { "id": "A0A8V0YQP5", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YQP5", "database": "AlphaFoldDB", "categories": [] }, { "id": "770397", "url": "https://www.ncbi.nlm.nih.gov/gene/770397", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR027812", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027812", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:770397", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:770397", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "GMPGKVE", "url": "https://omabrowser.org/oma/group/GMPGKVE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YQP5", "url": "https://www.orthodb.org/?gene=A0A8V0YQP5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR35673", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR35673", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR35673:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR35673:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15546", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15546", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_046759533", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046759533", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YQP5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQP5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQP5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQP5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MFALCPPDAPFPGGPALGTAFSGSVQRSPDSNCNFAGDDECDSNQNWSRAGGGGENTANPSDNLLLLAQRQMAQGGMGDVASSAACAPQQGERSPPEGAEVGEGEVGGSPAEDIGYASSSLSIDSPDSACGGAWDPPGDPAEVSEPPPEPLFPALAEAVQQLQEKERFKEREKEKHHVQLVMYRRLALLRWIHGLQQKVLEQQDRLQESFDTILDNRKELIRCMQHGAPCPTAAPNP", "length": 237, "header": "tr|A0A8V0YQP5-1|A0A8V0YQP5_CHICK Isoform 1 of Chromosome 1 open reading frame 216 OS=Gallus gallus OX=9031 GN=C1orf216 PE=4 SV=1 CANONICAL=A0A8V0YQP5-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YQP5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQP5/entry#A0A8V0YQP5-1", "sequence": { "sequence": "MFALCPPDAPFPGGPALGTAFSGSVQRSPDSNCNFAGDDECDSNQNWSRAGGGGENTANPSDNLLLLAQRQMAQGGMGDVASSAACAPQQGERSPPEGAEVGEGEVGGSPAEDIGYASSSLSIDSPDSACGGAWDPPGDPAEVSEPPPEPLFPALAEAVQQLQEKERFKEREKEKHHVQLVMYRRLALLRWIHGLQQKVLEQQDRLQESFDTILDNRKELIRCMQHGAPCPTAAPNP", "length": 237, "header": "tr|A0A8V0YQP5-1|A0A8V0YQP5_CHICK Isoform 1 of Chromosome 1 open reading frame 216 OS=Gallus gallus OX=9031 GN=C1orf216 PE=4 SV=1 CANONICAL=A0A8V0YQP5-1" }, "locus": { "chromosome": "23", "start_pos": 4610282, "end_pos": 4609572, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010036149.1", "url": "https://www.ensembl.org/id/ENSGALT00010036149.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021003.1", "url": "https://www.ensembl.org/id/ENSGALP00010021003.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 232, "start_aa": "Thr", "end_pos": 232, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr232", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:770397", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:770397", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287ARN3-1", "protein_name": "Chromosome 6 C1orf216 homolog", "gene_name": "C6H1orf216", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MFAVQPGVAEGAQFLGGPPPAVCPPELQADSNSNFMASAKDANENWPEMPGQVEPKVMRSSSRLPSDNQGFQVPGLPEGEVRCPPEGAEIPRAGPEKMGGASTVCSPLEDNGYASSSLSIDSSSCSPEPACGTPLGPGPSDPLLPSVAQAVQQLQAQERYKEQEKEKHHVHLVMYRRLALLQWIRGLQHQLVDQQARLQESFDTILDNRKELIRCLHQRAAPSRPQDQG", "length": 229 }, "evidence": [ { "id": "A0A8V0YQP5", "url": "https://omabrowser.org/oma/group/A0A8V0YQP5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0AAA9TR68-1", "protein_name": "Chromosome 3 C1orf216 homolog", "gene_name": "C3H1orf216", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MFAIQPGVAEGAQFLGGPPPGVCPSELQPDSNSNFMTSAKDTNENWHGMPGQVEPVVMRSSSELPSDNQDFQAPGLPEGEIRSPPEGAEIPGAGPEKTGGASTVCSPLEDNGYASSSLSVDSPSRSPESACGTPPGPPDHLLPSVAQAVQQLQAQERYKEQEKEKHHVHLVMYRRLALLQWIRGLQHQLVDQQARLQESFDTILDNRKELIRCLQQRAVPSGPRGQD", "length": 227 }, "evidence": [ { "id": "A0A8V0YQP5", "url": "https://omabrowser.org/oma/group/A0A8V0YQP5/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0ABK0LHC1-1", "protein_name": "Similar to human chromosome 1 open reading frame 216", "gene_name": "C5h1orf216", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFAAIQPGLAEGAQYLGSLPPGVCHPDLQPDSNSNFVESAKDANKNWHGVDPILIRSSSESPSDNRVFQATGLPEAGVRSPPEGAEIPGAEPEKSSDASSVCSPLEDIGYASSSLSISSFSSSAEAGCSTPRGPSPLDPLLPSVAQAVQQLQAQERYKEQEKEKHHVHLVMYRRLALLQWIRALQHQLVDQQARLQESFDTILDNRKELIRCLQHREGPCRHQDQG", "length": 226 }, "evidence": [ { "id": "A0A8V0YQP5", "url": "https://omabrowser.org/oma/group/A0A8V0YQP5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3H9V1-1", "protein_name": "UPF0500 protein C1orf216 homolog", "gene_name": "CUNH1orf216", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MFAAIQPGLAEGAQFLGGLPPGICQPELQPDNNSNFVDSAKDANKNWHGVPGKVEPLLRSSSESPSDNQVFQATGLLEAGVRSPPEGAEICGAEPEKSSGASNVCSPLEDIGYASSSLSIDSLSSSPEPICETPRGPSPLDPLLPSVARAVQQLQAQERYKEQEKEKHHVHLVMYRRLALLQWIRALQHQLVDQQARLQESFDTILDNRKELIRCLQQREAPCRHQDHC", "length": 229 }, "evidence": [ { "id": "A0A8V0YQP5", "url": "https://omabrowser.org/oma/group/A0A8V0YQP5/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q8BP99-1", "protein_name": "UPF0500 protein C1orf216 homolog", "gene_name": "", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFAAIQPGLAEGAQYPGSLPPGVCQPDLQPDNNSNFVESAKDANKNWHGVPGKVDPILIRSSSESPSDNQVFQATRLPEAGVRSPPEGAEIPGAEPEKLSGASSVCSPLEDIGYASSSLSIDSFSSSPEPVCDTPRGPSPLDPLLPSVAQAVQQLQAQERYKEQEKEKHHAHLVMYRRLALLQWIRALQHQLVDQQARLQESFDTILDNRKELIRCLQQREAPCRHQDQG", "length": 230 }, "evidence": [ { "id": "A0A8V0YQP5", "url": "https://omabrowser.org/oma/group/A0A8V0YQP5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8TAB5-1", "protein_name": "UPF0500 protein C1orf216", "gene_name": "C1orf216", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MFAIQPGLAEGGQFLGDPPPGLCQPELQPDSNSNFMASAKDANENWHGMPGRVEPILRRSSSESPSDNQAFQAPGSPEEGVRSPPEGAEIPGAEPEKMGGAGTVCSPLEDNGYASSSLSIDSRSSSPEPACGTPRGPGPPDPLLPSVAQAVQHLQVQERYKEQEKEKHHVHLVMYRRLALLQWIRGLQHQLIDQQARLQESFDTILDNRKELIRCLQQRAAPSRPQDQA", "length": 229 }, "evidence": [ { "id": "A0A8V0YQP5", "url": "https://omabrowser.org/oma/group/A0A8V0YQP5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 46, "end_pos": 48, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 232 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 46, "end_pos": 48 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YQQ2-1", "uniprot_ac": "A0A8V0YQQ2", "uniprot_id": "A0A8V0YQQ2_CHICK", "mass": { "chemical_mass": 115354.0, "monoisotopic_mass": 115354.0 }, "refseq": { "ac": "XP_025010782", "name": "synaptopodin isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025010782" }, "gene_names": [ { "name": "SYNPO", "type": "recommended", "evidence": [ { "id": "A0A8V0YQQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQQ2" } ] }, { "name": "SYNPO", "type": "synonym", "evidence": [ { "id": "XP_025010782", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025010782" } ] } ], "protein_names": [ { "name": "Synaptopodin", "type": "synonym", "evidence": [ { "id": "A0A8V0YQQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQQ2/entry#names_and_taxonomy" } ] }, { "name": "synaptopodin isoform X1", "type": "synonym", "evidence": [ { "id": "XP_025010782", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025010782" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052544.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_025010782.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_025010782", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025010782" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQQ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQQ2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SYNPO", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQQ2", "locus": { "chromosome": "13", "start_pos": 12685937, "end_pos": 12714311, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010016699", "url": "https://www.ensembl.org/id/ENSGALG00010016699" } ] } } ], "crossref": [ { "id": "A0A8V0YQQ2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YQQ2", "database": "AlphaFoldDB", "categories": [] }, { "id": "770421", "url": "https://www.ncbi.nlm.nih.gov/gene/770421", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR051976", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051976", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "HMSRKTN", "url": "https://omabrowser.org/oma/group/HMSRKTN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YQQ2", "url": "https://www.orthodb.org/?gene=A0A8V0YQQ2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YZ04", "url": "https://www.orthodb.org/?gene=A0A8V0YZ04", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24217", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24217", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24217:SF13", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24217:SF13", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "XP_025010782", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025010782", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YQQ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQQ2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQQ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQQ2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YZ04", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZ04", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YZ04-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZ04-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLKAPLRQESDRGDIPDPELPTGNVNNEPAAPPDCCAPSPAPQLPPTAVSPMDDPSQEWRLVKIKRVLIAPSTEPRKASLSRSSSLSEKELKEAKARSRRIVAQLTTAPGPSSKGVLLFHRRRQRVDGLTGTGTGHGTGLPLSLGAQPGDMETGEGHSSRGTLGEQEDVASRQESPTEAQQVPLSIYLKENMALAAANGVHKEKVESEVGGVQGTGDSLGTRVATPAPPESACVPKQKNGEVPSVPVVTANTPVGTASTSLGTVSMPTGTASMTMGTAGTPLGTDSVSMGTVTMPVVTANMTVRRAGTPIGMAGTPVVTASAPVVTASIPAGVAMANTAMGTASEPMVSANITTGTPSAPMVTASVPTGAASMPVGTASTHIVTTSVPMGTASSHTVAANIPMGMADAAMGTANAPMGTASPPTVTSNAPVVTSNIPTVTASTPPGTAPPATQAQSRAQSRQYYEVHLTLAKPKPVKNRTARPFGTQTPPGLSQPPERAPGTEPPPPTYAETLGSPPPLSRVRSPPTYSALYPPGEQKAPSGPSYGLAAVVPLPKTGILEESAARRGHKKSMFTFVEKPKLGPNPDLLDLVQSADIRKKQKEHGDPGAEDEPFALGAEAANFVPASASRAAQPLPVPDDAPAWSSCLKSPMVKPKPKPQPSHNLSEARGKGAELFARRQSRMEKFIIEAPSQPELLRSPSPTMSLPPSWKYDANACLSPMVSRHPTRSPSQPSKTPPASLYGNNPTENEAELSKHQPYQLQPSLFILSPSKAPARSMPPPRPSPPSTYSYPQQTSCPTSPLPPSPIWQPPTTHGAASSPFLSATGALPMTHSAGGGGAELLLASPCHGRSPRAKGGFQAPRPSYSTRNAGIEPQERRPSLPASPTWTPRLARHQGAQDGWASPVSVPELEQGPPRSPPWSERSLSPQRQDAEPRASRQMQARLARNIINAARRKSSSPKPPGPDGSRPFTPPAVGPPGLPQGCKAAAPQRARSVPAAPGSPSPSHRSPLTEGPCASPGVSRATWAEGRRLLLPPSPAGPSPTPKSPLPSPVVGARSPAKRYSSRSPTDSDVSIDSEDSGTKSPGIHSFNLCPRGWSGSLRLKAGGLPSGAHCTS", "length": 1114, "header": "tr|A0A8V0YQQ2-1|A0A8V0YQQ2_CHICK Isoform 1 of Synaptopodin OS=Gallus gallus OX=9031 GN=SYNPO PE=1 SV=1 CANONICAL=A0A8V0YQQ2-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YQQ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQQ2/entry#A0A8V0YQQ2-1", "sequence": { "sequence": "MLKAPLRQESDRGDIPDPELPTGNVNNEPAAPPDCCAPSPAPQLPPTAVSPMDDPSQEWRLVKIKRVLIAPSTEPRKASLSRSSSLSEKELKEAKARSRRIVAQLTTAPGPSSKGVLLFHRRRQRVDGLTGTGTGHGTGLPLSLGAQPGDMETGEGHSSRGTLGEQEDVASRQESPTEAQQVPLSIYLKENMALAAANGVHKEKVESEVGGVQGTGDSLGTRVATPAPPESACVPKQKNGEVPSVPVVTANTPVGTASTSLGTVSMPTGTASMTMGTAGTPLGTDSVSMGTVTMPVVTANMTVRRAGTPIGMAGTPVVTASAPVVTASIPAGVAMANTAMGTASEPMVSANITTGTPSAPMVTASVPTGAASMPVGTASTHIVTTSVPMGTASSHTVAANIPMGMADAAMGTANAPMGTASPPTVTSNAPVVTSNIPTVTASTPPGTAPPATQAQSRAQSRQYYEVHLTLAKPKPVKNRTARPFGTQTPPGLSQPPERAPGTEPPPPTYAETLGSPPPLSRVRSPPTYSALYPPGEQKAPSGPSYGLAAVVPLPKTGILEESAARRGHKKSMFTFVEKPKLGPNPDLLDLVQSADIRKKQKEHGDPGAEDEPFALGAEAANFVPASASRAAQPLPVPDDAPAWSSCLKSPMVKPKPKPQPSHNLSEARGKGAELFARRQSRMEKFIIEAPSQPELLRSPSPTMSLPPSWKYDANACLSPMVSRHPTRSPSQPSKTPPASLYGNNPTENEAELSKHQPYQLQPSLFILSPSKAPARSMPPPRPSPPSTYSYPQQTSCPTSPLPPSPIWQPPTTHGAASSPFLSATGALPMTHSAGGGGAELLLASPCHGRSPRAKGGFQAPRPSYSTRNAGIEPQERRPSLPASPTWTPRLARHQGAQDGWASPVSVPELEQGPPRSPPWSERSLSPQRQDAEPRASRQMQARLARNIINAARRKSSSPKPPGPDGSRPFTPPAVGPPGLPQGCKAAAPQRARSVPAAPGSPSPSHRSPLTEGPCASPGVSRATWAEGRRLLLPPSPAGPSPTPKSPLPSPVVGARSPAKRYSSRSPTDSDVSIDSEDSGTKSPGIHSFNLCPRGWSGSLRLKAGGLPSGAHCTS", "length": 1114, "header": "tr|A0A8V0YQQ2-1|A0A8V0YQQ2_CHICK Isoform 1 of Synaptopodin OS=Gallus gallus OX=9031 GN=SYNPO PE=1 SV=1 CANONICAL=A0A8V0YQQ2-1" }, "locus": { "chromosome": "13", "start_pos": 12707784, "end_pos": 12696891, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010040257.1", "url": "https://www.ensembl.org/id/ENSGALT00010040257.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023341.1", "url": "https://www.ensembl.org/id/ENSGALP00010023341.1" } ] } }, { "isoform_ac": "A0A8V0YZ04-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQQ2/entry#A0A8V0YZ04-1", "sequence": { "sequence": "METGEGHSSRGTLGEQEDVASRQESPTEAQQVPLSIYLKENMALAAANGVHKEKVESEVGGVQGTGDSLGTRVATPAPPESACVPKQKNGEVPSVPVVTANTPVGTASTSLGTVSMPTGTASMTMGTAGTPLGTDSVSMGTVTMPVVTANMTVRRAGTPIGMAGTPVVTASAPVVTASIPAGVAMANTAMGTASEPMVSANITTGTPSAPMVTASVPTGAASMPVGTASTHIVTTSVPMGTASSHTVAANIPMGMADAAMGTANAPMGTASPPTVTSNAPVVTSNIPTVTASTPPGTAPPATQAQSRAQSRQYYEVHLTLAKPKPVKNRTARPFGTQTPPGLSQPPERAPGTEPPPPTYAETLGSPPPLSRVRSPPTYSALYPPGEQKAPSGPSYGLAAVVPLPKTGILEESAARRGHKKSMFTFVEKPKLGPNPDLLDLVQSADIRKKQKEHGDPGAEDEPFALGAEAANFVPASASRAAQPLPVPDDAPAWSSCLKSPMVKPKPKPQPSHNLSEARGKGAELFARRQSRMEKFIIEAPSQPELLRSPSPTMSLPPSWKYDANACLSPMVSRHPTRSPSQPSKTPPASLYGNNPTENEAELSKHQPYQLQPSLFILSPSKAPARSMPPPRPSPPSTYSYPQQTSCPTSPLPPSPIWQPPTTHGAASSPFLSATGALPMTHSAGGGGAELLLASPCHGRSPRAKGGFQAPRPSYSTRNAGIEPQVWKPSFYYK", "length": 733, "header": "tr|A0A8V0YZ04-1|A0A8V0YZ04_CHICK Computationally mapped isoform of Synaptopodin OS=Gallus gallus OX=9031 GN=SYNPO PE=1 SV=1 CANONICAL=A0A8V0YQQ2-1" }, "locus": { "chromosome": "13", "start_pos": 12691185, "end_pos": 12688987, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010040262.1", "url": "https://www.ensembl.org/id/ENSGALT00010040262.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023344.1", "url": "https://www.ensembl.org/id/ENSGALP00010023344.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1042, "start_aa": "Thr", "end_pos": 1042, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1042", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 702, "start_aa": "Thr", "end_pos": 702, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr702", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "E1BA93-1", "protein_name": "Synaptopodin", "gene_name": "SYNPO", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MLGPHLPPLPPAPSEGGSTPCAFGVPDGSYRCLALEAEESGGEEGLQGEAGLTDLEEDQVASRSGDKTCRATQGPPQLPRALGTQPPSCSREARGVSQLDNRASQAGDPVKFRQVMTASLSPSPGPRVAQKPALGRSTSLTEKDLKEAKARSQQIAAQLTTPPSSNSRGVQLFNRRRQRVNEFTLESHGQRGPKSSQEPLRVPPASPTGHAPGLSLSSTSLPEPGPPRNPACQSADTGVPSHSMEGCSEEASLLRHLEKMASEEEEVPLVVYLKENAALLTANGLHLSQNREAQQSPPTPPPEEVHSPAADANQNLPSTGTTLVTPASNGNHSLPATDVNQNLSAAITPQSLPLSSVQQNSSEVQLPPNDVVPDFKPSTQCAGGQPQEPAVEVRSSTLLIDKVSAPPTATSTFSREVTPISSSRPLGPDFMSSSLLIDVQLGAPVVSTEQEMSGRTTATTPTKLYSEVHLTLAKPPSVVNRTARPFGIQAPGSTGQMERSPMVERRHRGEKTPVPQPPSVADRSPRPQRHVISHSPMLERRPVAQRSPALERRPLGNFTPPPTYAETLSTAPLTSGVRSPPSYSALYPSSDSKPSHLKGQAVPASKTGILEESMARRGSRKSMFTFVEKPKVTPNPDLLDLVQTADEKRRQRDQGEAGLEEEPFALGAEASNFQQEPAPRDRASPADAEETIPEWASCLKSPRIQAKPKPKPNQNLSEASGKGAELYARRQSRMEKYVIESSGHAELARCPSPTMSLPSSWKYSTNTPGGTFRVASRSPARTPPASLFHGYLPENGVLRPEPTKQPPYQLRPSLFVLSPIKEPAKPSPRAASPAKPSSLDLVPSLPKAALPPSPALPRPSRSYTTTGQDGLQPTAVSPTYSSDISPVSPSRAWSPRAKQAPRPSFSTRNAGIEAQDRRESLPTSPPWTPGASRPPSSLDGWVSPGPWEPGRGSSMSSPPPLPPPPPMSPSWSERSVSPLRSETEVRPPSRQLQALLARNIINAARRKSASPRPAGAESLRPFSPPRAPPPPPPPPPPPPRMRSPQPSRPGPAAAPGATFAPIPRSPLPAPPRPFPYRRSPTDSDVSLDSEDSGAKSPGILGYNICPRGWNGSLRLKRGNLPTEASCTT", "length": 1128 }, "evidence": [ { "id": "A0A8V0YQQ2", "url": "https://omabrowser.org/oma/group/A0A8V0YQQ2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q8CC35-1", "protein_name": "Synaptopodin", "gene_name": "Synpo", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLGAHFPPPPLGASEGRAAPCTFQIPDGSYRCLALEAEESSSEDGLQGEVRLVDLEEEGTSQSRANHGTPPLSRAPAIIQPSSCHREARGGFQRSDRPSHDWDVVQARKVMTASGSSSPVPRVAQKPALGRSTSFTENDLKEAKARSQQIAAQLTTPPSSNSRGVQLFNRRRQRVNEFTLESRGQRSPKLNQEALQTGRPLSPIGHAPGPSVKPTSPSKPGSPKHPSPQSPSRGVAGHIMEGYSEEASLLRHLEKVASEEEEVPLVVYLKENAALLTANGLHLSQSRETQQSSPNPPDTEVPSPAADINQNPSSPNATLTTLASSSHHSQPTADINQNPPAAITPVPQNSSQAQCSPNGTLDSKPGTLCADDGQSPVPAEEVRSSILLIDKVSAPPSAASTFSREATPLSSSGPPAADLMSSSLLIDMQPSTLVAPAEQEVPGHVAVTTPTKVYSEVHLTLAKPASVVNRTARPFGIQSPGTSQIEQSPMMGRRQFGEKAWAPPASSMADRSPQPQRHIMSRSPMVERRLLGQRSPVLERRPLGNFTPPPTYAETLSTAPVASRVRSPPSYSTLYPSSDPKPSHLKGQVAPANKTGILEESMARRGSRKSMFTFVEKPKVTPNPDLLDLVQTADEKRRQRDHGEVGMEEEPFALGAEASNFQQEPIARDRASPAAAEEAVPEWASCLKSPRIQAKPKPKPNQNLSEASGKGAELYARRQSRMEKYVIESSGHAELARCPSPTMSLPSSWKYTTNAPGGFRVASLSPARTPPASLYHGYLPENGVLRPEPTKQQPYQMRPSLYALSPVKEPAKASSRATSSRTPSRTVSPRAASPAKPSSLDLVPNLPRAGLPPSPALPRPSRSSPGLYTAPVQDSLQPTAVSPTYSSDISPVSPSRAWSPRAKQAPRPSFSTRNAGIEAQVWKPSFCFK", "length": 929 }, "evidence": [ { "id": "A0A8V0YQQ2", "url": "https://omabrowser.org/oma/group/A0A8V0YQQ2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9Z327-1", "protein_name": "Synaptopodin", "gene_name": "Synpo", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLGTHFPPPPLGPSEGRAAPCTFQIPDGSYRCLALEAEESSSEDGLQGEVRLVDLEEEGTSKSRVNHGTPPLSRAPAIIQPSSCCREARGGFQHSDKPSREWDVVQARKVMTASVSSSPVPRVAQKPALGRSTSFTEKDLKEAKERSQRIAAQLTTPPSSNSRGVQLFNRRRQRVNEFTLESRGQRSPKLSQEALQTGHPSSPIGHAPGLSVNPTSPSKPGSPKHSSSQSPSRGVPGHIMEGYSEEASLLRHLEKVASEEEEVPLVVYLKENAALLTANGLHLSQNRETQQSSPNPPETEEVPSPAADINQNPSSPNATLTTAASNSHHNQPTADVNQNPPATITPVQQNSSETQCSPNGTLDSKPNTPSADDGQRPVPAEEVRSSILLIDKVSAPPSAASPFSREATPLSSSGPPAADLMSSSLLIGMQPSTLVASAEQEVSGHAAVTTPTKVYSEVHLTLAKPASVVNRTARPFGMQSPGTTSQIEQSPMMGRRHFGEKAWAPPASSMADRSPQPQRHIMARSPMVERRLVGQRSPVVERRPLGNFTPPPTYAETLSTAPVASQVRSPPSYSTLYPSSDPKPPHLKGQVVPANKTGILEESMARRGSRKSMFTFVEKPKVTPNPDLLDLVQTADEKRRQRDQGEVGMEDEPFALGAEASNFQQEPIARDRSGPAAAEETVPEWASCLKSPRIQAKPKPKPNQNLSEASGKGAELYARRQSRMEKYVIESSGHAELARCPSPTMSLPSSWKYTTNAPGGFRVASLSPARTPPASLYHGYLPENGVLRPEPTKQQPHQMRPSLYALSPVKEPAKISSRATSSRASSRTVSPRAASPAKPSSLDLVPNLPRAGLPPSPALPRPSRSSPGLYNAPVQDSLQPTAVSPTYSSDISPVSPSRAWSPRAKQAPRPSFSTRNAGIEAQVWKPSFCFK", "length": 931 }, "evidence": [ { "id": "A0A8V0YQQ2", "url": "https://omabrowser.org/oma/group/A0A8V0YQQ2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "positive regulation of actin filament bundle assembly", "id": "GO:0032233", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032233", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQQ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQQ2" } ], "pmid": "" }, { "name": "spine apparatus assembly", "id": "GO:1905355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905355", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQQ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQQ2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "actin binding", "id": "GO:0003779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003779", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQQ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQQ2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 8, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQQ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQQ2" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQQ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQQ2" } ], "pmid": "" }, { "name": "actin cytoskeleton", "id": "GO:0015629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015629", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQQ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQQ2" } ], "pmid": "" }, { "name": "stress fiber", "id": "GO:0001725", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001725", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQQ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQQ2" } ], "pmid": "" }, { "name": "Z disc", "id": "GO:0030018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030018", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQQ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQQ2" } ], "pmid": "" }, { "name": "spine apparatus", "id": "GO:0097444", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097444", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQQ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQQ2" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQQ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQQ2" } ], "pmid": "" }, { "name": "organelle", "id": "GO:0043226", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043226", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQQ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQQ2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 300, "end_pos": 302, "annotation": "n_glycosylation_sequon" }, { "start_pos": 351, "end_pos": 353, "annotation": "n_glycosylation_sequon" }, { "start_pos": 478, "end_pos": 480, "annotation": "n_glycosylation_sequon" }, { "start_pos": 663, "end_pos": 665, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 702, 1042 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 300, "end_pos": 302 }, { "start_pos": 351, "end_pos": 353 }, { "start_pos": 478, "end_pos": 480 }, { "start_pos": 663, "end_pos": 665 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YQR5-1", "uniprot_ac": "A0A8V0YQR5", "uniprot_id": "A0A8V0YQR5_CHICK", "mass": { "chemical_mass": 60865.0, "monoisotopic_mass": 60865.0 }, "refseq": { "ac": "NP_001384123", "name": "protein NOXP20 isoform 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384123" }, "gene_names": [ { "name": "FAM114A1", "type": "recommended", "evidence": [ { "id": "A0A8V0YQR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQR5" } ] }, { "name": "FAM114A1", "type": "synonym", "evidence": [ { "id": "NP_001384123", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384123" } ] } ], "protein_names": [ { "name": "Family with sequence similarity 114 member A1", "type": "synonym", "evidence": [ { "id": "A0A8V0YQR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQR5/entry#names_and_taxonomy" } ] }, { "name": "protein NOXP20 isoform 1", "type": "synonym", "evidence": [ { "id": "NP_001384123", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384123" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: SRR13267661.20220.1, SRR13267659.38853.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA103992290, SAMEA103992323 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000074.1. On Nov 3, 2021 this sequence version replaced XP_015141139.3. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001384123", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384123" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQR5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQR5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "FAM114A1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQR5", "locus": { "chromosome": "4", "start_pos": 68991128, "end_pos": 69022944, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010015039", "url": "https://www.ensembl.org/id/ENSGALG00010015039" } ] } } ], "crossref": [ { "id": "A0A8V0YQR5", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YQR5", "database": "AlphaFoldDB", "categories": [] }, { "id": "426196", "url": "https://www.ncbi.nlm.nih.gov/gene/426196", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR007998", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007998", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "WSTWGKS", "url": "https://omabrowser.org/oma/group/WSTWGKS/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YQR5", "url": "https://www.orthodb.org/?gene=A0A8V0YQR5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YXG7", "url": "https://www.orthodb.org/?gene=A0A8V0YXG7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12842", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12842", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12842:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12842:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05334", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05334", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001384123", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384123", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YQR5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQR5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQR5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQR5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YXG7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXG7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YXG7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXG7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSEDLCDGIPPEEKPEVMEMPCSDVLPQESLLHPVEAEIVPASSPHEQGRATQGASNGQKGDVFINENPLPEEIAESLPSNGDVTEDVPTECIETVSLDTEPEPEETPPEESSSAADSSKASRWGAWGSWGKSLLSSASATVGHGITAVREKAETTLGIHHASSAPSEAAEHPAAETSVTQAEDYPDQSSSENIPPSPSSGSRGMLSAITNAVQNTGKSVLSGGLDALEFIGKTTMNVLAENDPGFKRTKTLMARTVSLSQLLREAKEKERQRRAQQVTVERTAHYGLLFDEFQGLSHLEALEILSNESENQIQSYLETLDGEQLEAVKSDLIAIKEIFVPAESDDEVVQAQKADMGEEFVSMLTELLFELHVAATPDKLNKARKKAHKWLEEASLSTSADIEEKLEEKPGEPDEEKTEEGKDKIDNDKSEVNKSKTVEEIYMLSIESLAEVTARCIEQLHKVAELILHGQEVEKTAQDQAKVLTNLTSAMCNEVSSLSKKFSDSLTAAGSSMKAEVLNPIIDSVLLEGCNSTTYVQDAFQLLLPVLQISHIQTSCLKTQK", "length": 561, "header": "tr|A0A8V0YQR5-1|A0A8V0YQR5_CHICK Isoform 1 of Family with sequence similarity 114 member A1 OS=Gallus gallus OX=9031 GN=FAM114A1 PE=1 SV=1 CANONICAL=A0A8V0YQR5-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YQR5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQR5/entry#A0A8V0YQR5-1", "sequence": { "sequence": "MSEDLCDGIPPEEKPEVMEMPCSDVLPQESLLHPVEAEIVPASSPHEQGRATQGASNGQKGDVFINENPLPEEIAESLPSNGDVTEDVPTECIETVSLDTEPEPEETPPEESSSAADSSKASRWGAWGSWGKSLLSSASATVGHGITAVREKAETTLGIHHASSAPSEAAEHPAAETSVTQAEDYPDQSSSENIPPSPSSGSRGMLSAITNAVQNTGKSVLSGGLDALEFIGKTTMNVLAENDPGFKRTKTLMARTVSLSQLLREAKEKERQRRAQQVTVERTAHYGLLFDEFQGLSHLEALEILSNESENQIQSYLETLDGEQLEAVKSDLIAIKEIFVPAESDDEVVQAQKADMGEEFVSMLTELLFELHVAATPDKLNKARKKAHKWLEEASLSTSADIEEKLEEKPGEPDEEKTEEGKDKIDNDKSEVNKSKTVEEIYMLSIESLAEVTARCIEQLHKVAELILHGQEVEKTAQDQAKVLTNLTSAMCNEVSSLSKKFSDSLTAAGSSMKAEVLNPIIDSVLLEGCNSTTYVQDAFQLLLPVLQISHIQTSCLKTQK", "length": 561, "header": "tr|A0A8V0YQR5-1|A0A8V0YQR5_CHICK Isoform 1 of Family with sequence similarity 114 member A1 OS=Gallus gallus OX=9031 GN=FAM114A1 PE=1 SV=1 CANONICAL=A0A8V0YQR5-1" }, "locus": { "chromosome": "4", "start_pos": 69020764, "end_pos": 68993589, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010036176.1", "url": "https://www.ensembl.org/id/ENSGALT00010036176.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021023.1", "url": "https://www.ensembl.org/id/ENSGALP00010021023.1" } ] } }, { "isoform_ac": "A0A8V0YXG7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQR5/entry#A0A8V0YXG7-1", "sequence": { "sequence": "MSEDLCDGIPPEEKPEVMEMPCSDVLPQESLLHPVEAEIVPASSPHEQGRATQGASNGQKGDVFINENPLPEEIAESLPSNGDVTEDVPTECIETVSLDTEPEPEETPPEESSSAADSSKASRWGAWGSWGKSLLSSASATVGHGITAVREKAETTLGIHHASSAPSEAAEHPAAETSVTQAEDYPDQSSSENIPPSPSSGSRGMLSAITNAVQNTGKSVLSGGLDALEFIGKTTMNVLAENDPGFKRTKTLMARTVSLSQLLREAKEKERQRRAQQVTVERTAHYGLLFDEFQGLSHLEALEILSNESENQIQSYLETLDGEQLEAVKSDLIAIKEIFVPAESDDEVVQAQKDMGEEFVSMLTELLFELHVAATPDKLNKARKKAHKWLEEASLSTSADIEEKLEEKPGEPDEEKTEEGKDKIDNDKSEVNKSKTVEEIYMLSIESLAEVTARCIEQLHKVAELILHGQEVEKTAQDQAKVLTNLTSAMCNEVSSLSKKFSDSLTAAGSSMKAEVLNPIIDSVLLEGCNSTTYVQDAFQLLLPVLQISHIQTSCLKTQK", "length": 560, "header": "tr|A0A8V0YXG7-1|A0A8V0YXG7_CHICK Computationally mapped isoform of Family with sequence similarity 114 member A1 OS=Gallus gallus OX=9031 GN=FAM114A1 PE=1 SV=1 CANONICAL=A0A8V0YQR5-1" }, "locus": { "chromosome": "4", "start_pos": 69020764, "end_pos": 68993589, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010036165.1", "url": "https://www.ensembl.org/id/ENSGALT00010036165.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021012.1", "url": "https://www.ensembl.org/id/ENSGALP00010021012.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "D4A777-1", "protein_name": "Family with sequence similarity 114, member A1", "gene_name": "Fam114a1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSDDAHDAIDNGGGEDAAEMPNSPAEDAEVRCGPAMTSNEPAPAHHTGEQSEVSAAACAEVTPTGLLDQSKASDADETPLNGEVTEDTLVECIDSVSLEGDTGSEIPLKEQNDVAVDSSPPTGRWAGWGSWGKSLLSSASATVGHGLTAVKEKAGATLRIHSVNSGSPEGALTDAENRISQNVTPDQDPAGGPHTPPPPGTAGSRGVLSALTNAVQNTGKSVLTGGLDALEFIGKKTMNVLAESDPGFKRTKTLMERTVSLSQMLREAKEKEKQRLAQQLTAERTAHYGMLFDEYQGLSHLEALEILSNESESKVQSFLASLDGEKLEFLKNDLISIKDIFVAKESENEENPEEQGLEESGEEFARMLTELLFELHVAATPDKLNKAMKKAHDWVEEDQSVVSIDVTKGSEEEEKKEGKEEKAEEPEEDKAGGKGAKTVEEVYMLSIESLAEVTARCIEQLHKVAELILHGQEEEKPAQDQAKVLIRLTTAMCNEVASLSKKFTNVLTTVGSNKKAEVLNPMIDSVLLEGCNSTTYVQDALQLLLPVLQVSHIHTSCSKATAQPDSS", "length": 567 }, "evidence": [ { "id": "A0A8V0YQR5", "url": "https://omabrowser.org/oma/group/A0A8V0YQR5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8IWE2-1", "protein_name": "Protein NOXP20", "gene_name": "FAM114A1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSDDAGDTLATGDKAEVTEMPNSDSLPEDAEVHCDSAAVSHEPTPADPRGEGHENAAVQGAGAAAIGPPVQPQDANALEPPLNGDVTEDTLAECIDSVSLEAEPRSEIPLQEQNYLAVDSPPSGGGWAGWGSWGKSLLSSASATVGHGLTAVKEKAGATLRIHGVNSGSSEGAQPNTENGVPEITDAATDQGPAESPPTSPSSASRGMLSAITNVVQNTGKSVLTGGLDALEFIGKKTMNVLAESDPGFKRTKTLMERTVSLSQMLREAKEKEKQRLAQQLTMERTAHYGMLFDEYQGLSHLEALEILSNESESKVQSFLASLDGEKLELLKNDLISIKDIFAAKELENEENQEEQGLEEKGEEFARMLTELLFELHVAATPDKLNKAMKRAHDWVEEDQTVVSVDVAKVSEEETKKEEKEEKSQDPQEDKKEEKKTKTIEEVYMSSIESLAEVTARCIEQLHKVAELILHGQEEEKPAQDQAKVLIKLTTAMCNEVASLSKKFTNSLTTVGSNKKAEVLNPMISSVLLEGCNSTTYIQDAFQLLLPVLQVSHIQTSCLKAQP", "length": 563 }, "evidence": [ { "id": "A0A8V0YQR5", "url": "https://omabrowser.org/oma/group/A0A8V0YQR5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9D281-1", "protein_name": "Protein Noxp20", "gene_name": "Fam114a1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSDDARDTIANGVGEDAAEMPNSDSPAEDAAEVQCGPATTSNEPAPDDHMEEQPEITAMCAESTPPGILDQSKASAADETPLNGEVTEDTLVECVDSVSLEGDTGSEIPLKEQDDAAVDPSSQAGRWAGWGSWGKSLLSSASATVGHGLTAVKEKAGATLRIHSANSASPEGAPTDAENGISGNVTPDQDPARGPHTPPPPGAAGSRGMLSALTNVVQNTGKSVLTGGLDALEFIGKKTMIVLAESDPGFKRTKTLMERTVSLSQMLREAKEKEKQRLAQQLTVERTAHYGMLFDEYQGLSHLEALEILSNESESKVQSFLTSLDGEKLELLKNDLISIKDIFVAKESENEANPEEQGLEESGEEFARMLTELLFELHVAATPDKLNKAMKKAHDWVEEDQSVVSIDVAKGSEEEEKEEGKEEKAEEPEEDKTGGQGAKTVEEVYMLSIESLAEVTARCIEQLHKVAELILHGQEEEKPAQDQARVLIKLTTAMCNEVTSLSKKFTNSLTTVGSNKKAEVLNPMINSVFLEGSNSTTYVQDALQLLLPVLQVSHIRTSCLKATAQPDCS", "length": 569 }, "evidence": [ { "id": "A0A8V0YQR5", "url": "https://omabrowser.org/oma/group/A0A8V0YQR5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": 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"https://www.uniprot.org/uniprotkb/A0A8V0YQS1" } ] }, { "name": "C5orf34", "type": "synonym", "evidence": [ { "id": "XP_040512500", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040512500" } ] } ], "protein_names": [ { "name": "Chromosome 5 open reading frame 34", "type": "synonym", "evidence": [ { "id": "A0A8V0YQS1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQS1/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein C5orf34 homolog isoform X1", "type": "synonym", "evidence": [ { "id": "XP_040512500", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040512500" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052572.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 1, 2022 this sequence version replaced XP_040512500.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040512500", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040512500" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQS1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQS1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "C5orf34", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQS1", "locus": { "chromosome": "Z", "start_pos": 14244139, "end_pos": 14255706, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010014476", "url": "https://www.ensembl.org/id/ENSGALG00010014476" } ] } } ], "crossref": [ { "id": "A0A8V0YQS1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YQS1", "database": "AlphaFoldDB", "categories": [] }, { "id": "427194", "url": "https://www.ncbi.nlm.nih.gov/gene/427194", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR027830", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027830", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027865", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027865", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR053899", "url": "https://www.ebi.ac.uk/interpro/entry/IPR053899", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR053900", "url": "https://www.ebi.ac.uk/interpro/entry/IPR053900", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR053901", "url": "https://www.ebi.ac.uk/interpro/entry/IPR053901", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "TAVISWC", "url": "https://omabrowser.org/oma/group/TAVISWC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YQS1", "url": "https://www.orthodb.org/?gene=A0A8V0YQS1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YVU4", "url": "https://www.orthodb.org/?gene=A0A8V0YVU4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR34531", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR34531", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR34531:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR34531:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15016", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15016", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF15025", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15025", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF22833", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22833", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF22834", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22834", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_040512500", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040512500", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YQS1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQS1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQS1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQS1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YVU4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YVU4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YVU4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YVU4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAERLMVLYGDDSVEVHYADGARLLLSPCGSEYLYEEALPAAAHPLQPAESTRQRVPFVLSAYREQILRALDFRNTFSSRPYLPSRIISPERKRIIFSDIVEVRWPDPVSADLTRCIKNGSVKISSVDGYAHLYLSELQQEFTVEFLCKVSQPFAKSANQPSHFSPKNSNYETEDQYGKSSKNSVPEMSSKQVRIDNKNNEDGHAEGKYREATKPNNQRDRGGVPLFYTNCTSEYTWVTQRWSVSSCPEEWKYPLSLALMCHSLHTAKNVLKTCEENDRTSIGADVSTDPKTYEAVSRLPAALPVSCRAPHLHRWSFCDFFLQRNEDSEQYSYPQLIQIVWCEGVFYRFIHGRRNITEIYPGDESLLKSEGDFLGNYFVHYAIQKGIKKREEKMYSVNSLPPDVPGSQYSVSSIITAATKMLQYCYKTKLSLIHNYHLCCWKMVPETDGREMLPVLLYEKVIHGTGRLLVYSDHKVHAAFWDGISLNMVWDFSSCYKKIQVNEDVGWCKLTTPDGVQQLIQIRHPGIYERYIRTVIGWCRSLNESKETPELTTHTVTEENWCADAELEKIQRFNFLLDNSNVLEGTSAAKNNLSIRKTESGSGPEEMSEGHVLEALQNTSRIIQDIESLLASAGK", "length": 636, "header": "tr|A0A8V0YQS1-1|A0A8V0YQS1_CHICK Isoform 1 of Chromosome 5 open reading frame 34 OS=Gallus gallus OX=9031 GN=C5orf34 PE=4 SV=1 CANONICAL=A0A8V0YQS1-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YQS1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQS1/entry#A0A8V0YQS1-1", "sequence": { "sequence": "MAAERLMVLYGDDSVEVHYADGARLLLSPCGSEYLYEEALPAAAHPLQPAESTRQRVPFVLSAYREQILRALDFRNTFSSRPYLPSRIISPERKRIIFSDIVEVRWPDPVSADLTRCIKNGSVKISSVDGYAHLYLSELQQEFTVEFLCKVSQPFAKSANQPSHFSPKNSNYETEDQYGKSSKNSVPEMSSKQVRIDNKNNEDGHAEGKYREATKPNNQRDRGGVPLFYTNCTSEYTWVTQRWSVSSCPEEWKYPLSLALMCHSLHTAKNVLKTCEENDRTSIGADVSTDPKTYEAVSRLPAALPVSCRAPHLHRWSFCDFFLQRNEDSEQYSYPQLIQIVWCEGVFYRFIHGRRNITEIYPGDESLLKSEGDFLGNYFVHYAIQKGIKKREEKMYSVNSLPPDVPGSQYSVSSIITAATKMLQYCYKTKLSLIHNYHLCCWKMVPETDGREMLPVLLYEKVIHGTGRLLVYSDHKVHAAFWDGISLNMVWDFSSCYKKIQVNEDVGWCKLTTPDGVQQLIQIRHPGIYERYIRTVIGWCRSLNESKETPELTTHTVTEENWCADAELEKIQRFNFLLDNSNVLEGTSAAKNNLSIRKTESGSGPEEMSEGHVLEALQNTSRIIQDIESLLASAGK", "length": 636, "header": "tr|A0A8V0YQS1-1|A0A8V0YQS1_CHICK Isoform 1 of Chromosome 5 open reading frame 34 OS=Gallus gallus OX=9031 GN=C5orf34 PE=4 SV=1 CANONICAL=A0A8V0YQS1-1" }, "locus": { "chromosome": "Z", "start_pos": 14255663, "end_pos": 14244554, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034781.1", "url": "https://www.ensembl.org/id/ENSGALT00010034781.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020384.1", "url": "https://www.ensembl.org/id/ENSGALP00010020384.1" } ] } }, { "isoform_ac": "A0A8V0YVU4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQS1/entry#A0A8V0YVU4-1", "sequence": { "sequence": "MAAERLMVLYGDDSVEVHYADGARLLLSPCGSEYLYEEALPAAAHPLQPAESTRQRVPFVLSAYREQILRALDFRNTFSSRPYLPSRIISPERKRIIFSDIVEVRWPDPVSADLTRCIKNGSVKISSVDGYAHLYLSELQQEFTVEFLCKVSQPFAKSANQPSHFSPKNSNYETEDQYGKSSKNSVPEMSSKQVRIDNKNNEDGHAEGKYREATKPNNQRDRGGVPLFYTNCTSEYTWVTQRWSVSSCPEEWKYPLSLALMCHSLHTAKNVLKTCEENDRTSIGADVSTDPKTYEAVSRLPAALPVSCRAPHLHRWSFCDFFLQRNEDSEQYSYPQLIQIVWCEGVFYRFIHGRRNITEIYPGDESLLKSEGDFLGNYFVHYAIQKGIKKREEKMYSVNSLPPDVPGSQYSVSSIITAATKMLQYCYKTKLSLIHNYHLCCWKMVPETDGREMLPVLLYEKVIHGTGRLLVYSDHKVHAAFWDGISLNMVWDFSSCYKKIQVNEDVGWCKLTTPDGVQQLIQIRHPGIYERYIRTVIGWCRSLNESKETPELTTHTVTEENWCADAELEKIQRFNCILLKAISYSYSYLYPELPF", "length": 595, "header": "tr|A0A8V0YVU4-1|A0A8V0YVU4_CHICK Computationally mapped isoform of Chromosome 5 open reading frame 34 OS=Gallus gallus OX=9031 GN=C5orf34 PE=4 SV=1 CANONICAL=A0A8V0YQS1-1" }, "locus": { "chromosome": "Z", "start_pos": 14255663, "end_pos": 14244798, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034788.1", "url": "https://www.ensembl.org/id/ENSGALT00010034788.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020387.1", "url": "https://www.ensembl.org/id/ENSGALP00010020387.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A4FUB0-1", "protein_name": "Uncharacterized protein C5orf34 homolog", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAAEVQMVLYEDDSVQVQYIDGSRLQLSPCGSEFLFEKAPPVSAHPLQQPERIRQRTHFVISAYREQLQRALDFRNSFATCPFLSESIIPSEMKTRILIDVSEVRWPSLDTGDGMTYMQSGTVRISSLDGHAYLCLPKSQHEFTVHFLCKVSQKPDSSIEVSEKNNKGKKDKQVEKAGKICTRGSLSGQRLKNKENELYHQIMKSEEPSEKSCVNGAKGREVLSSPHPKDTCIYTWVKQCWSVASCPEEWKYPLSLALHFHDKISSMSGIDADITQKRMLTSDVSEERGKEVSVLPRALLLSCPAPHLHRWNFSDSLSQKQFGEEEYSYHELVKVVWYKGVTYRLTHKHMNSIEIYPGDGSVFKSEGAYLGNYFTYYSIREESEEREEKTYAVNNLPPDRPGSPFSVCSLIKQATRILQHCAKMRLSLSHNYRVCCWKMVPGINDSSVLPLLLRESFVPGVGRFLAYSDDKVHAIFLDGITLTLNWNFGSFIEKRQVNRGLTLGWCKLTFPDGQNQLIQIQHPRPYERYVTTVISWCRRLTQISQQEIPIHPSSSVPEESWSVASELEKIQKFNLLLESSGVLNQTSNKKNKQSLDRCKPKSSETLLKEVNEKSVSVALKKTSEILQDIDNLLSNSKW", "length": 638 }, "evidence": [ { "id": "A0A8V0YQS1", "url": "https://omabrowser.org/oma/group/A0A8V0YQS1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q3UJC8-1", "protein_name": "Uncharacterized protein C5orf34 homolog", "gene_name": "", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGMAAEVRMVLYEDDSVQVHYACGSTLQLSPCGSEFLFEKALPPSTHPLEQPERIRQRTHFVISNYREQLQRALDFRNSSATCPFLSESIIPPERKKHIFIDFSEVEWPSLDRDDCIMYSESGVVKITSLDGHAYLCLPRSQHEFTVHFLCKVSQRPDSSGILSETQNQDPKNKLVEKTRKVCRCGNLSEQTLRNKENEPPYQILKSKNASVNTCCVNDSEGRGELPSLGTNHRCVYAWVKQAWSVAACPEAWKHPLSLALRFYNKVRAASEIDADFPASSIVTSDCPEERGTEVSVLPRALLLSCPAPHMHRWTFCDSLLQRQPDAEDFSYPELVKVVWYKGVTYRLTHKNVNSIEIFPGDGSVFKSEGAHFGNYFTYYPSQEESEKREEKTYSVNNLPPDRPGNFFSVRSLIKQATRILQHCAKIRLSLSHNYRVCCWKMAPGVSVSTILPVLLKESLIPGVGRFLAYSDDKVHAVFLDGVTVTLNWHLSSSAEKKQVDQGLSFGWCRLTFPDGQDQLIPTEHPGAYERYVTSVISWCRGLTQTSPRQVPTHLSPALKENWSVASELEKIQKFNWLLENSGVLNLTSSKNEQCSGHCKSGSSETLLEATNEERVSVALKRTSEILQDIDRLLSLSRK", "length": 639 }, "evidence": [ { "id": "A0A8V0YQS1", "url": "https://omabrowser.org/oma/group/A0A8V0YQS1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q6AYM1-1", "protein_name": "Uncharacterized protein C5orf34 homolog", "gene_name": "", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGTAAEVRMVLYEDDSVQVNYADGSTLQLSPCGSEFLFEKAPPPSTHPLEQPERIRQRTHFVISNYREQLQRALDFRNSSATCPFLSESIIPSERKKRVFIDFSEVEWPSPDRDDCITYSESGIVKITSLDGHAYLCLPRSQHEFTVHFLCKVSQKPDSSVMPPETKNRVPKEELVGKTRNVCRSGRLSGQRLRNKENEPPRQLLTSKNASANIHCVSETEGREELPSPGTKRRYVHVWVKQSWSAASCPEEWKYPLSLGLRFYNKVPAASAADAEVPVSGIVTSDNPEERGTGVSVLPRALLLSCSAPHMHRWNFCDSLLQRQSDAEEYSYPELIKVVWYKGVTYRLTHKNVNSIEIFPGDGSVFKSEGTHFGNYFTYSSQDNSGKREEKTYSVNNLPPDRPGNLYSVRSLIKQATRILQHCAKIRLSLSHNYRVCCWRMAPGVNVSSILPVLLKESLIPGVGRFLAYSDDKVHAVFLDGVTLTLNWDLSSSAEKTQVDQGLRLRWCRLTFPDGQDQLIQTEHPGVYERYVTSVVTWCRRLTQTSSRHVSPRLSPVPEENWSVASELEKIQKFNWLLENSGVLNLTSGKKNEQCSSDHCKPGSSETLPEATNEESVSVALKRTSEVLQDIDYLLSLTRK", "length": 640 }, "evidence": [ { "id": "A0A8V0YQS1", "url": "https://omabrowser.org/oma/group/A0A8V0YQS1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q96MH7-1", "protein_name": "Uncharacterized protein C5orf34", "gene_name": "C5orf34", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAELRMILYEDDSVQVQYVDGSTLQLSPCGSEFLFEKSPPVSAHPLEQPERIRQRTHFVISTYREQLQRALDFRNSSATCPFLSETIIPSERKKHIFIDITEVRWPSLDTDGTMIYMESGIVKITSLDGHAYLCLPRSQHEFTVHFLCKVSQKSDSSAVLSETNNKAPKDKLVEKTGKICIRGNLPGQRLKNKENEFHCQIMKSKETLKKMSCVNGTEGREELPSPGTKHTCVYTWVKQCWSVAACPEEWKYPLSLALHFHNKISNMSKIDAHITQSRFLTSDISEERGKVVSVLPRALSLSCPVPHLHRWNFCDSLLQRQSDEYSYPELVKMVWYKGVTYRLTHQNMNSIEIYSGDGSVFKSEGAYFGNYFTYYSIQEGSGKREEKTYSVNNLPPDRPGSPFTVGSLIKQATRILQHCVKMRLSLSHNYRICCWKMVPGINDSNILPLVLKESLIPSVGRFLAYSDDKVHAIFLDGITLTLNWNFSSPIEKRQVNQGLNLGWCKLTFPDGQEQLIQIEHPEPYERYVTTVTSWCRRLTQTSPREMPTHSSSSVLQENWSVASELEKIQKFNLLLENSGILNQISNKKNEQQSFDHYKPGSSETLLGEVNENRVSIALKKTSEILHDIDCLLSNSKK", "length": 638 }, "evidence": [ { "id": "A0A8V0YQS1", "url": "https://omabrowser.org/oma/group/A0A8V0YQS1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 120, "end_pos": 122, "annotation": "n_glycosylation_sequon" }, { "start_pos": 231, "end_pos": 233, "annotation": "n_glycosylation_sequon" }, { "start_pos": 356, "end_pos": 358, "annotation": "n_glycosylation_sequon" }, { "start_pos": 544, "end_pos": 546, "annotation": "n_glycosylation_sequon" }, { "start_pos": 593, "end_pos": 595, "annotation": "n_glycosylation_sequon" }, { "start_pos": 619, "end_pos": 621, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YQS1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQS1" }, { "id": "PF22834", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22834" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C5orf34-like", "eco_id": "ECO_0000259", "start_pos": 338, "end_pos": 423, "start_aa": "Ile", "end_aa": "Leu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0YQS1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQS1" }, { "id": "PF15016", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15016" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C5orf34-like C-terminal", "eco_id": "ECO_0000259", "start_pos": 453, "end_pos": 542, "start_aa": "Met", "end_aa": "Ser", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0YQS1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQS1" }, { "id": "PF15025", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15025" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C5orf34-like N-terminal", "eco_id": "ECO_0000259", "start_pos": 7, "end_pos": 76, "start_aa": "Met", "end_aa": "Asn", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0YQS1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQS1" }, { "id": "PF22833", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22833" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C5orf34-like second", "eco_id": "ECO_0000259", "start_pos": 120, "end_pos": 259, "start_aa": "Asn", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 120, "end_pos": 122 }, { "start_pos": 231, "end_pos": 233 }, { "start_pos": 356, "end_pos": 358 }, { "start_pos": 544, "end_pos": 546 }, { "start_pos": 593, "end_pos": 595 }, { "start_pos": 619, "end_pos": 621 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YQT0-1", "uniprot_ac": "A0A8V0YQT0", "uniprot_id": "A0A8V0YQT0_CHICK", "mass": { "chemical_mass": 50081.0, "monoisotopic_mass": 50081.0 }, "refseq": { "ac": "XP_414955", "name": "uncharacterized protein C7orf26 homolog", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_414955" }, "gene_names": [ { "name": "C7orf26", "type": "recommended", "evidence": [ { "id": "A0A8V0YQT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQT0" } ] }, { "name": "C7orf26", "type": "synonym", "evidence": [ { "id": "XP_414955", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_414955" } ] } ], "protein_names": [ { "name": "Integrator complex subunit 15", "type": "synonym", "evidence": [ { "id": "A0A8V0YQT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQT0/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein C7orf26 homolog", "type": "synonym", "evidence": [ { "id": "XP_414955", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_414955" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052545.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_414955.3. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_414955", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_414955" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQT0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQT0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "C7orf26", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQT0", "locus": {} } ], "crossref": [ { "id": "A0A8V0YQT0", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YQT0", "database": "AlphaFoldDB", "categories": [] }, { "id": "416658", "url": "https://www.ncbi.nlm.nih.gov/gene/416658", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR027844", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027844", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:416658", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416658", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DDGDCHQ", "url": "https://omabrowser.org/oma/group/DDGDCHQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YQT0", "url": "https://www.orthodb.org/?gene=A0A8V0YQT0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14540", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14540", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14540:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14540:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF14964", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14964", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_414955", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_414955", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YQT0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQT0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQT0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQT0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSDIRHSLLRRDALSAAKEVLYHLDIYFSSQLQSAPLPLVDKGPAELLEEFLFQVPKERGAPPKRLNSLQELQLLEIMCNYFQEQTKDSVRQIIFSSLFSPQGNKADDNRMALLGKLVSMAVAVCRVPVLECAAFWLQRTPAVFCVRLAQALVDDYCNLVPGSIQTLKQIFSASPRFCCQFITAVTALYDLSSDDLIPPSDLLELIVSWIFEDPRLILITFLNTPIAANLPIGFLELTPLTGLIRWCVKAPLAYKRRKKASLSNGHPTSKIAKDSTEGDDGDCHQLYSKLHLSVLQVLMMLQGHLTEKNLYGRLGLIPFDHVVPLVEEINRLSDELNPLNASKEIELALDRLAQALQVAMASGALLCTRDDLRTVCSRLPHNNLLQLVISGPVQQPAHSALPPGFYPHIHTPPLGYPAHAAHPALPAHPALPAHPVQTFIPGMTFPYRPIR", "length": 451, "header": "tr|A0A8V0YQT0-1|A0A8V0YQT0_CHICK Isoform 1 of Integrator complex subunit 15 OS=Gallus gallus OX=9031 GN=C7orf26 PE=1 SV=1 CANONICAL=A0A8V0YQT0-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YQT0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQT0/entry#A0A8V0YQT0-1", "sequence": { "sequence": "MSDIRHSLLRRDALSAAKEVLYHLDIYFSSQLQSAPLPLVDKGPAELLEEFLFQVPKERGAPPKRLNSLQELQLLEIMCNYFQEQTKDSVRQIIFSSLFSPQGNKADDNRMALLGKLVSMAVAVCRVPVLECAAFWLQRTPAVFCVRLAQALVDDYCNLVPGSIQTLKQIFSASPRFCCQFITAVTALYDLSSDDLIPPSDLLELIVSWIFEDPRLILITFLNTPIAANLPIGFLELTPLTGLIRWCVKAPLAYKRRKKASLSNGHPTSKIAKDSTEGDDGDCHQLYSKLHLSVLQVLMMLQGHLTEKNLYGRLGLIPFDHVVPLVEEINRLSDELNPLNASKEIELALDRLAQALQVAMASGALLCTRDDLRTVCSRLPHNNLLQLVISGPVQQPAHSALPPGFYPHIHTPPLGYPAHAAHPALPAHPALPAHPVQTFIPGMTFPYRPIR", "length": 451, "header": "tr|A0A8V0YQT0-1|A0A8V0YQT0_CHICK Isoform 1 of Integrator complex subunit 15 OS=Gallus gallus OX=9031 GN=C7orf26 PE=1 SV=1 CANONICAL=A0A8V0YQT0-1" }, "locus": { "chromosome": "14", "start_pos": 12333381, "end_pos": 12327463, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010040297.1", "url": "https://www.ensembl.org/id/ENSGALT00010040297.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023367.1", "url": "https://www.ensembl.org/id/ENSGALP00010023367.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:416658", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416658", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "F1M0G5-1", "protein_name": "Integrator complex subunit 15", "gene_name": "Ints15", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSDIRHSLLRRDALSAAKEVLYHLDIYFSSQLQSAPLPIVDKGSVELLEEFVFQVPKERGAQPKRLNSLQELQLLEIMCSYFQEQSKDSVRQIIFSSLFSPQGNKADDSRMSLLGKLVSMAVAVCRIPVLECAASWLQRTPVVYCVRLARALVDDYCCLVPGSVQTLKQIFSASPRFCCQFITSVTALYDLSSDDLIPPLDLLEMIVSWIFEDPRLILITFLNTPIAANLPIGFLELTPLIGLIRWCVKAPLAYKRKKPCLSNGHISHKVAKDSGTGTDRDSHLLYSQLHLSVLQVLTTLQLHLTEKNLYGRLGLILFDHMVPLVEEINRLADELNPLNASQEIELALDRLAQALQVAMTSGALLCTRDDLRTLCSRLPHNNLLQLVISGPVQQSPHTALPPGFYPHIHTPPLAYGAVPAHPAAHPALPTHPGHTFLSGVTFPFRPIR", "length": 448 }, "evidence": [ { "id": "A0A8V0YQT0", "url": "https://omabrowser.org/oma/group/A0A8V0YQT0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q7ZTY6-1", "protein_name": "Integrator complex subunit 15", "gene_name": "ints15", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSDIRHALLRRDPLSAAKEVLYHLDISLGSALQSSAGPPAGLEKSTVELVEEFIFHVSKDRNIQSKRMSCVQELQLLEIICSYFQEQSKDAIRQVIFSALFSLQGNKADESRMAMLGKLVSMSIAVCRVPILECAAIWLQRTHSAWCVRLAQVLMEDYCTLVPCAISTLQNICSASPRFCCQLITAVTALYDFSTDELTPPPALLEMLVGWITEDPRLLLLTFINSPLNSSLPLGCLEITPLLGLLRWCVKAPLAYHRGRKSAMTNGHGDGEKGTAYEELYSKLHLSVLQVFLMLQVHLTEKNMFCRLTVLPVESVAALIEEVGRLCEKLAPLLDASHIQLALDRLAQALQVAMATGALLCAREDLRALCSRLPHNNLLQLVMSGPVVQPPPHSSPFQPNMYPHIHPGRPSPLSPHSPHQSTLSSPHSPHTVLTAHPTHPALAPHRPLTAHATHPALSPHAFHPASIAFPYRPIR", "length": 475 }, "evidence": [ { "id": "A0A8V0YQT0", "url": "https://omabrowser.org/oma/group/A0A8V0YQT0/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q8BGA7-1", "protein_name": "Integrator complex subunit 15", "gene_name": "Ints15", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSDIRHSLLRRDALSAAKEVLYHLDIYFSSQLQSAPLPIVDKGSVELLEEFVFQVPKERGAQPKRLNSLQELQLLEIMCSYFQEQSKDSVRQIIFSSLFSPQGNKADDSRMSLLGKLVSMAVAVCRIPVLECAASWLQRTPVVYCVRLARVLVEDYCCLVPGSVQTLKQIFSASPRFCCQFITSVTALYDLSSDDLIPPLDLLEMIVSWIFEDPRLILITFLNTPIAANLPIGFLELTPLIGLIRWCVKAPLAYKRKKPCLSNGHISHKVAKDSGASTDRDSHLLYSKLHLSVLQVLMTLQLHLTEKNLYGRLGLILFDHMVPLVEEINRLADELNPLNASQEIELALDRLAQALQVAMTSGALLCTRDDLRTLCSRLPHNNLLQLVISGPVQQSPHTALPPGFYPHIHTPPLAYGAVPAHPAAHPALPTHPGHTFISGVTFPFRPIR", "length": 448 }, "evidence": [ { "id": "A0A8V0YQT0", "url": "https://omabrowser.org/oma/group/A0A8V0YQT0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96N11-1", "protein_name": "Integrator complex subunit 15", "gene_name": "INTS15", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSDIRHSLLRRDALSAAKEVLYHLDIYFSSQLQSAPLPIVDKGPVELLEEFVFQVPKERSAQPKRLNSLQELQLLEIMCNYFQEQTKDSVRQIIFSSLFSPQGNKADDSRMSLLGKLVSMAVAVCRIPVLECAASWLQRTPVVYCVRLAKALVDDYCCLVPGSIQTLKQIFSASPRFCCQFITSVTALYDLSSDDLIPPMDLLEMIVTWIFEDPRLILITFLNTPIAANLPIGFLELTPLVGLIRWCVKAPLAYKRKKKPPLSNGHVSNKVTKDPGVGMDRDSHLLYSKLHLSVLQVLMTLQLHLTEKNLYGRLGLILFDHMVPLVEEINRLADELNPLNASQEIELSLDRLAQALQVAMASGALLCTRDDLRTLCSRLPHNNLLQLVISGPVQQSPHAALPPGFYPHIHTPPLGYGAVPAHPAAHPALPTHPGHTFISGVTFPFRPIR", "length": 449 }, "evidence": [ { "id": "A0A8V0YQT0", "url": "https://omabrowser.org/oma/group/A0A8V0YQT0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VPF9-1", "protein_name": "Integrator complex subunit 15", "gene_name": "IntS15", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSMSIDSNKLLLRKGDMKLDNYPTCAVEALTRLETLIASRNKQNMVMQIISEFIFLERTPKDGDVRKSQALPISQMNLFQEFQLIIALIEYFSRPGRDATRNAIFLSLFGSHLTPQRSKLLSRLISTAVSGSVAPLLSSAGTWMQQVGCKTPLSLEVAQNIVSDFISYSRKTPEQLKQLPMVGPHFAANFMVAVADLYLNEQRSPTLNPPPDALLDTITEWMMENPTLCQASQQPLVLPAGAIAMPFTTPLAGLLRWVVLAPLVSNRSAYSNLHLSLLRALQQLVSSGESTALPSQDLMQIVKSLQSYCARLAESKTDPQADAAYQKCMERFAQAVQIALSSNCITNQIQLLCLLESLPPHKLMKIVIEAHKK", "length": 373 }, "evidence": [ { "id": "A0A8V0YQT0", "url": "https://omabrowser.org/oma/group/A0A8V0YQT0/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "regulation of transcription elongation by RNA polymerase II", "id": "GO:0034243", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034243", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQT0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQT0" } ], "pmid": "" }, { "name": "RNA polymerase II transcription initiation surveillance", "id": "GO:0160240", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160240", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQT0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQT0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "chromosome", "id": "GO:0005694", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005694", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQT0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQT0" } ], "pmid": "" }, { "name": "integrator complex", "id": "GO:0032039", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032039", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQT0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQT0" } ], "pmid": "" }, { "name": "INTAC complex", "id": "GO:0160232", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160232", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQT0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQT0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 340, "end_pos": 342, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 340, "end_pos": 342 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": 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"recommended", "evidence": [ { "id": "A0A8V0YQT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQT3" } ] } ], "protein_names": [ { "name": "Reticulon", "type": "recommended", "evidence": [ { "id": "A0A8V0YQT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQT3/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQT3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQT3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RTN4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQT3", "locus": { "chromosome": "3", "start_pos": 2739734, "end_pos": 2680747, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010016706", "url": "https://www.ensembl.org/id/ENSGALG00010016706" } ] } } ], "crossref": [ { "id": "A0A8V0YQT3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YQT3", "database": "AlphaFoldDB", "categories": [] }, { "id": "378790", "url": "https://www.ncbi.nlm.nih.gov/gene/378790", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003388", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003388", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046964", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046964", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YQT3", "url": "https://www.orthodb.org/?gene=A0A8V0YQT3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YQV1", "url": "https://www.orthodb.org/?gene=A0A8V0YQV1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YQV4", "url": "https://www.orthodb.org/?gene=A0A8V0YQV4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YX69", "url": "https://www.orthodb.org/?gene=A0A8V0YX69", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YXL7", "url": "https://www.orthodb.org/?gene=A0A8V0YXL7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YXM4", "url": "https://www.orthodb.org/?gene=A0A8V0YXM4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YXN8", "url": "https://www.orthodb.org/?gene=A0A8V0YXN8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YXP1", "url": "https://www.orthodb.org/?gene=A0A8V0YXP1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z489", "url": "https://www.orthodb.org/?gene=A0A8V0Z489", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z4A4", "url": "https://www.orthodb.org/?gene=A0A8V0Z4A4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45799", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45799", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45799:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45799:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02453", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02453", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-193634", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-193634", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YQT3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQT3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQT3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQT3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQV1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQV1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQV1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQV1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQV4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQV4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQV4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQV4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YX69", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YX69", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YX69-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YX69-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YXL7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXL7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YXL7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXL7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YXM4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXM4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YXM4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXM4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YXN8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXN8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YXN8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXN8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YXP1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXP1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YXP1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXP1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z489", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z489", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z489-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z489-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z4A4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4A4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z4A4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4A4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVTEKVVDLQEQPGSAKSLGQEDFTAVPLDTAASLLSFSPLSADPFKEHAAFDSVSDALPARGIYKESASEVCKEAMENVRNPFLAEGNKRDISEMKYSEMEPSFTKAEAATIFQAEEMQLEGPKELCDLEKMPAQPLIMSPETPEDLFEKNEEDIFSSKDKGRDGDSGDKKALKEDAIRREEYVDFKQYEPVWEVEGAGHGLSGLREDIESNIDAKLETSLDEKYGEDKLSVLKDYERDSEGSAEDLSFPNSPEAVKEPSQNYITCTKFESSVTPDGSKVKSICPIEEDTSENRTDDEKKIAEMKAQNTEQGDFSSQAIGKQEGLEADDAKTGSISTLLSDTAASMPEGLTPDLVQEAYESEMHDAACTKLAYETKIDLVQTSESVQETLKPVTQLCPSFEDSEAAPSPVLPDIVMEAPLSSGTAGAEASTVQLETSQLGTFVTTASYENVKKEAEKPPLYQEAVNMPLTQAQEAKEELTLKKADRESSTSPEDLETPYISIACDLIKETKVSGESASPSLTDYSTTPITEHLSQDVSEHKELAEKLSPQFGKCDLFSRQVMPDFPGKESEDQTLILNGKSVENIETDEEQERLVDSLAATGKPYLESFQDELDSSKIVTTQPSEPTPAKIAKAEKIPLQMEELNALAYSTDVSVATEPKPGDSKGLSPSSPVSVEDDFVMLVDPKTGTEFVAEVTDRETVHKNESKDISNEIRDEKRQAPLTELPCDLSVRNVEVKTEDDAHALKKSLQAIDREVPEVSMVSLPATGTSPSSTEKEIVSVGKPEAFEKEAERGAASAKEKEKPTAVFSAKLNVSSVVDLLYWRDIKKTGVVFGASLFLLLSLTVFSIVSVTAYIALALLSVTISFRIYKGVIQAIQKSDEGHPFRAYLESDVAVSEELIQKYSSVVLGHINGTVKELRRLFLVDDLVDSLKFAVLMWVFTYVGALFNGLTLLILALISLFSVPVIYERHQAQIDHYLGLVNKNVKDAMAKIQAKIPGLKRKTE", "length": 1005, "header": "tr|A0A8V0YQT3-1|A0A8V0YQT3_CHICK Isoform 1 of Reticulon OS=Gallus gallus OX=9031 GN=RTN4 PE=1 SV=1 CANONICAL=A0A8V0YQT3-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YQT3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQT3/entry#A0A8V0YQT3-1", "sequence": { "sequence": "MVTEKVVDLQEQPGSAKSLGQEDFTAVPLDTAASLLSFSPLSADPFKEHAAFDSVSDALPARGIYKESASEVCKEAMENVRNPFLAEGNKRDISEMKYSEMEPSFTKAEAATIFQAEEMQLEGPKELCDLEKMPAQPLIMSPETPEDLFEKNEEDIFSSKDKGRDGDSGDKKALKEDAIRREEYVDFKQYEPVWEVEGAGHGLSGLREDIESNIDAKLETSLDEKYGEDKLSVLKDYERDSEGSAEDLSFPNSPEAVKEPSQNYITCTKFESSVTPDGSKVKSICPIEEDTSENRTDDEKKIAEMKAQNTEQGDFSSQAIGKQEGLEADDAKTGSISTLLSDTAASMPEGLTPDLVQEAYESEMHDAACTKLAYETKIDLVQTSESVQETLKPVTQLCPSFEDSEAAPSPVLPDIVMEAPLSSGTAGAEASTVQLETSQLGTFVTTASYENVKKEAEKPPLYQEAVNMPLTQAQEAKEELTLKKADRESSTSPEDLETPYISIACDLIKETKVSGESASPSLTDYSTTPITEHLSQDVSEHKELAEKLSPQFGKCDLFSRQVMPDFPGKESEDQTLILNGKSVENIETDEEQERLVDSLAATGKPYLESFQDELDSSKIVTTQPSEPTPAKIAKAEKIPLQMEELNALAYSTDVSVATEPKPGDSKGLSPSSPVSVEDDFVMLVDPKTGTEFVAEVTDRETVHKNESKDISNEIRDEKRQAPLTELPCDLSVRNVEVKTEDDAHALKKSLQAIDREVPEVSMVSLPATGTSPSSTEKEIVSVGKPEAFEKEAERGAASAKEKEKPTAVFSAKLNVSSVVDLLYWRDIKKTGVVFGASLFLLLSLTVFSIVSVTAYIALALLSVTISFRIYKGVIQAIQKSDEGHPFRAYLESDVAVSEELIQKYSSVVLGHINGTVKELRRLFLVDDLVDSLKFAVLMWVFTYVGALFNGLTLLILALISLFSVPVIYERHQAQIDHYLGLVNKNVKDAMAKIQAKIPGLKRKTE", "length": 1005, "header": "tr|A0A8V0YQT3-1|A0A8V0YQT3_CHICK Isoform 1 of Reticulon OS=Gallus gallus OX=9031 GN=RTN4 PE=1 SV=1 CANONICAL=A0A8V0YQT3-1" }, "locus": { "chromosome": "3", "start_pos": 2736165, "end_pos": 2711947, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010040304.1", "url": "https://www.ensembl.org/id/ENSGALT00010040304.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023372.1", "url": "https://www.ensembl.org/id/ENSGALP00010023372.1" } ] } }, { "isoform_ac": "A0A8V0YQV1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQT3/entry#A0A8V0YQV1-1", "sequence": { "sequence": "MDELDQSPLISSSGPPRPTPSPGTERPAPPQPEPRRRVSSSGSADETLFALPATSEPLMHSSAEKVVDLQEQPGSAKSLGQEDFTAVPLDTAASLLSFSPLSADPFKEHAAFDSVSDALPARGIYKESASEVCKEAMENVRNPFLAEGNKRDISEMKYSEMEPSFTKAEAATIFQAEEMQLEGPKELCDLEKMPAQPLIMSPETPEDLFEKNEEDIFSSKDKGRDGDSGDKKALKEDAIRREEYVDFKQYEPVWEVEGAGHGLSGLREDIESNIDAKLETSLDEKYGEDKLSVLKDYERDSEGSAEDLSFPNSPEAVKEPSQNYITCTKFESSVTPDGSKVKSICPIEEDTSENRTDDEKKIAEMKAQNTEQGDFSSQAIGKQEGLEADDAKTGSISTLLSDTAASMPEGLTPDLVQEAYESEMHDAACTKLAYETKIDLVQTSESVQETLKPVTQLCPSFEDSEAAPSPVLPDIVMEAPLSSGTAGAEASTVQLETSQLGTFVTTASYENVKKEAEKPPLYQEAVNMPLTQAQEAKEELTLKKADRESSTSPEDLETPYISIACDLIKETKVSGESASPSLTDYSTTPITEHLSQDVSEHKELAEKLSPQFGKCDLFSRQVMPDFPGKESEDQTLILNGKSVENIETDEEQERLVDSLAATGKPYLESFQDELDSSKIVTTQPSEPTPAKIAKAEKIPLQMEELNALAYSTDVSVATEPKPGDSKGLSPSSPVSVEDDFVMLVDPKTGTEFVAEVTDRETVHKNESKDISNEIRDEKRQAPLTELPCDLSVRNVEVKTEDDAHALKKSLQAIDREVPEVSMVSLPATGTSPSSTEKEIVSVGKPEAFEKEAERGAASAKEKEKPTAVFSAKLNVSSVVDLLYWRDIKKTGVVFGASLFLLLSLTVFSIVSVTAYIALALLSVTISFRIYKGVIQAIQKSDEGHPFRAYLESDVAVSEELIQKYSSVVLGHINGTVKELRRLFLVDDLVDSLKFAVLMWVFTYVGALFNGLTLLILGEQQLICNISCLTFQAQIDHYLGLVNKNVKDAMAKIQAKIPGLKRKTE", "length": 1064, "header": "tr|A0A8V0YQV1-1|A0A8V0YQV1_CHICK Computationally mapped isoform of Reticulon OS=Gallus gallus OX=9031 GN=RTN4 PE=1 SV=1 CANONICAL=A0A8V0YQT3-1" }, "locus": { "chromosome": "3", "start_pos": 2736165, "end_pos": 2692036, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010040326.1", "url": "https://www.ensembl.org/id/ENSGALT00010040326.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023387.1", "url": "https://www.ensembl.org/id/ENSGALP00010023387.1" } ] } }, { "isoform_ac": "A0A8V0YQV4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQT3/entry#A0A8V0YQV4-1", "sequence": { "sequence": "MDELDQSPLISSSGPPRPQQPQFNYQFVLDDEKEEDEEEEEEEEDEDFDEQLEVMERKPIVATQERPSPPQDRSSPAEPPRPAAPEPAPEPLQPAWCLPQPAASSSSSSAASTPSPGTERPAPPQPEPRRRVSSSGSADETLFALPATSEPLMHSSAEKVVDLQEQPGSAKSLGQEDFTAVPLDTAASLLSFSPLSADPFKEHAAFDSVSDALPARGIYKESASEVCKEAMENVRNPFLAEGNKRDISEMKYSEMEPSFTKAEAATIFQAEEMQLEGPKELCDLEKMPAQPLIMSPETPEDLFEKNEEDIFSSKDKGRDGDSGDKKALKEDAIRREEYVDFKQYEPVWEVEGAGHGLSGLREDIESNIDAKLETSLDEKYGEDKLSVLKDYERDSEGSAEDLSFPNSPEAVKEPSQNYITCTKFESSVTPDGSKVKSICPIEEDTSENRTDDEKKIAEMKAQNTEQGDFSSQAIGKQEGLEADDAKTGSISTLLSDTAASMPEGLTPDLVQEAYESEMHDAACTKLAYETKIDLVQTSESVQETLKPVTQLCPSFEDSEAAPSPVLPDIVMEAPLSSGTAGAEASTVQLETSQLGTFVTTASYENVKKEAEKPPLYQEAVNMPLTQAQEAKEELTLKKADRESSTSPEDLETPYISIACDLIKETKVSGESASPSLTDYSTTPITEHLSQDVSEHKELAEKLSPQFGKCDLFSRQVMPDFPGKESEDQTLILNGKSVENIETDEEQERLVDSLAATGKPYLESFQDELDSSKIVTTQPSEPTPAKIAKAEKIPLQMEELNALAYSTDVSVATEPKPGDSKGLSPSSPVSVEDDFVMLVDPKTGTEFVAEVTDRETVHKNESKDISNEIRDEKRQAPLTELPCDLSVRNVEVKTEDDAHALKKSLQAIDREVPEVSMVSLPATGTSPSSTEKEIVSVGKPEAFEKEAERGAASAKEKEKPTAVFSAKLNVSSVVDLLYWRDIKKTGVVFGASLFLLLSLTVFSIVSVTAYIALALLSVTISFRIYKGVIQAIQKSDEGHPFRAYLESDVAVSEELIQKYSSVVLGHINGTVKELRRLFLVDDLVDSLKAQIDHYLGLVNKNVKDAMAKIQAKIPGLKRKTE", "length": 1120, "header": "tr|A0A8V0YQV4-1|A0A8V0YQV4_CHICK Computationally mapped isoform of Reticulon OS=Gallus gallus OX=9031 GN=RTN4 PE=1 SV=1 CANONICAL=A0A8V0YQT3-1" }, "locus": { "chromosome": "3", "start_pos": 2736165, "end_pos": 2692036, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010040334.1", "url": "https://www.ensembl.org/id/ENSGALT00010040334.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023392.1", "url": "https://www.ensembl.org/id/ENSGALP00010023392.1" } ] } }, { "isoform_ac": "A0A8V0YX69-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQT3/entry#A0A8V0YX69-1", "sequence": { "sequence": "MNGGGTHSSARLCLRAATGRDETLFALPATSEPLMHSSAEKVVDLQEQPGSAKSLGQEDFTAVPLDTAASLLSFSPLSADPFKEHAAFDSVSDALPARGIYKESASEVCKEAMENVRNPFLAEGNKRDISEMKYSEMEPSFTKAEAATIFQAEEMQLEGPKELCDLEKMPAQPLIMSPETPEDLFEKNEEDIFSSKDKGRDGDSGDKKALKEDAIRREEYVDFKQYEPVWEVEGAGHGLSGLREDIESNIDAKLETSLDEKYGEDKLSVLKDYERDSEGSAEDLSFPNSPEAVKEPSQNYITCTKFESSVTPDGSKVKSICPIEEDTSENRTDDEKKIAEMKAQNTEQGDFSSQAIGKQEGLEADDAKTGSISTLLSDTAASMPEGLTPDLVQEAYESEMHDAACTKLAYETKIDLVQTSESVQETLKPVTQLCPSFEDSEAAPSPVLPDIVMEAPLSSGTAGAEASTVQLETSQLGTFVTTASYENVKKEAEKPPLYQEAVNMPLTQAQEAKEELTLKKADRESSTSPEDLETPYISIACDLIKETKVSGESASPSLTDYSTTPITEHLSQDVSEHKELAEKLSPQFGKCDLFSRQVMPDFPGKESEDQTLILNGKSVENIETDEEQERLVDSLAATGKPYLESFQDELDSSKIVTTQPSEPTPAKIAKAEKIPLQMEELNALAYSTDVSVATEPKPGDSKGLSPSSPVSVEDDFVMLVDPKTGTEFVAEVTDRETVHKNESKDISNEIRDEKRQAPLTELPCDLSVRNVEVKTEDDAHALKKSLQAIDREVPEVSMVSLPATGTSPSSTEKEIVSVGKPEAFEKEAERGAASAKEKEKPTAVFSAKLNVSSVVDLLYWRDIKKTGVVFGASLFLLLSLTVFSIVSVTAYIALALLSVTISFRIYKGVIQAIQKSDEGHPFRAYLESDVAVSEELIQKYSSVVLGHINGTVKELRRLFLVDDLVDSLKFAVLMWVFTYVGALFNGLTLLILALISLFSVPVIYERHQAQIDHYLGLVNKNVKDAMAKIQAKIPGLKRKTE", "length": 1041, "header": "tr|A0A8V0YX69-1|A0A8V0YX69_CHICK Computationally mapped isoform of Reticulon OS=Gallus gallus OX=9031 GN=RTN4 PE=1 SV=1 CANONICAL=A0A8V0YQT3-1" }, "locus": { "chromosome": "3", "start_pos": 2736165, "end_pos": 2709139, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010040311.1", "url": "https://www.ensembl.org/id/ENSGALT00010040311.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023374.1", "url": "https://www.ensembl.org/id/ENSGALP00010023374.1" } ] } }, { "isoform_ac": "A0A8V0YXL7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQT3/entry#A0A8V0YXL7-1", "sequence": { "sequence": "MHSSAEKVVDLQEQPGSAKSLGQEDFTAVPLDTAASLLSFSPLSADPFKEHAAFDSVSDALPARGIYKESASEVCKEAMENVRNPFLAEGNKRDISEMKYSEMEPSFTKAEAATIFQAEEMQLEGPKELCDLEKMPAQPLIMSPETPEDLFEKNEEDIFSSKDKGRDGDSGDKKALKEDAIRREEYVDFKQYEPVWEVEGAGHGLSGLREDIESNIDAKLETSLDEKYGEDKLSVLKDYERDSEGSAEDLSFPNSPEAVKEPSQNYITCTKFESSVTPDGSKVKSICPIEEDTSENRTDDEKKIAEMKAQNTEQGDFSSQAIGKQEGLEADDAKTGSISTLLSDTAASMPEGLTPDLVQEAYESEMHDAACTKLAYETKIDLVQTSESVQETLKPVTQLCPSFEDSEAAPSPVLPDIVMEAPLSSGTAGAEASTVQLETSQLGTFVTTASYENVKKEAEKPPLYQEAVNMPLTQAQEAKEELTLKKADRESSTSPEDLETPYISIACDLIKETKVSGESASPSLTDYSTTPITEHLSQDVSEHKELAEKLSPQFGKCDLFSRQVMPDFPGKESEDQTLILNGKSVENIETDEEQERLVDSLAATGKPYLESFQDELDSSKIVTTQPSEPTPAKIAKAEKIPLQMEELNALAYSTDVSVATEPKPGDSKGLSPSSPVSVEDDFVMLVDPKTGTEFVAEVTDRETVHKNESKDISNEIRDEKRQAPLTELPCDLSVRNVEVKTEDDAHALKKSLQAIDREVPEVSMVSLPATGTSPSSTEKEIVSVGKPEAFEKEAERGAASAKEKEKPTAVFSAKLNVSSVVDLLYWRDIKKTGVVFGASLFLLLSLTVFSIVSVTAYIALALLSVTISFRIYKGVIQAIQKSDEGHPFRAYLESDVAVSEELIQKYSSVVLGHINGTVKELRRLFLVDDLVDSLKFAVLMWVFTYVGALFNGLTLLILGPDRPLFGTSEQERQRCDGKDPSKDPWAEAQN", "length": 990, "header": "tr|A0A8V0YXL7-1|A0A8V0YXL7_CHICK Computationally mapped isoform of Reticulon OS=Gallus gallus OX=9031 GN=RTN4 PE=1 SV=1 CANONICAL=A0A8V0YQT3-1" }, "locus": { "chromosome": "3", "start_pos": 2736161, "end_pos": 2711095, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010040313.1", "url": "https://www.ensembl.org/id/ENSGALT00010040313.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023376.1", "url": "https://www.ensembl.org/id/ENSGALP00010023376.1" } ] } }, { "isoform_ac": "A0A8V0YXM4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQT3/entry#A0A8V0YXM4-1", "sequence": { "sequence": 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"https://www.ensembl.org/id/ENSGALP00010023378.1" } ] } }, { "isoform_ac": "A0A8V0Z4A4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQT3/entry#A0A8V0Z4A4-1", "sequence": { "sequence": 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"length": 1159, "header": "tr|A0A8V0Z4A4-1|A0A8V0Z4A4_CHICK Computationally mapped isoform of Reticulon OS=Gallus gallus OX=9031 GN=RTN4 PE=1 SV=1 CANONICAL=A0A8V0YQT3-1" }, "locus": { "chromosome": "3", "start_pos": 2736165, "end_pos": 2692036, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010040330.1", "url": "https://www.ensembl.org/id/ENSGALT00010040330.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023388.1", "url": "https://www.ensembl.org/id/ENSGALP00010023388.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 628, "start_aa": "Thr", "end_pos": 628, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr628", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "R-GGA-193634", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-193634", "resource": "Reactome", "description": "Axonal growth inhibition (RHOA activation)" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 7, "go_terms": [ { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQT3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQT3" } ], "pmid": "" }, { "name": "glutamatergic synapse", "id": "GO:0098978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098978", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQT3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQT3" } ], "pmid": "" }, { "name": "nuclear envelope", "id": "GO:0005635", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005635", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQT3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQT3" } ], "pmid": "" }, { "name": "postsynaptic density", "id": "GO:0014069", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0014069", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQT3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQT3" } ], "pmid": "" }, { "name": "neuronal cell body", "id": "GO:0043025", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043025", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQT3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQT3" } ], "pmid": "" }, { "name": "neuron projection", "id": "GO:0043005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043005", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQT3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQT3" } ], "pmid": "" }, { "name": "endoplasmic reticulum tubular network membrane", "id": "GO:0098826", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098826", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQT3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQT3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 20, "go_terms": [ { "name": "positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction", "id": "GO:0051897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051897", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQT3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQT3" } ], "pmid": "" }, { "name": "negative regulation of amyloid-beta formation", "id": "GO:1902430", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902430", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQT3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQT3" } ], "pmid": "" }, { "name": "brain development", "id": "GO:0007420", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007420", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQT3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQT3" } ], "pmid": "" }, { "name": "protein stabilization", "id": "GO:0050821", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050821", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQT3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQT3" } ], "pmid": "" }, { "name": "neuron differentiation", "id": "GO:0030182", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030182", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQT3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQT3" } ], "pmid": "" }, { "name": "modulation of chemical synaptic transmission", "id": "GO:0050804", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050804", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQT3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQT3" } ], "pmid": "" }, { "name": "cerebral cortex radial glia-guided migration", "id": "GO:0021801", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021801", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQT3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQT3" } ], "pmid": "" }, { "name": "axonal fasciculation", "id": "GO:0007413", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007413", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQT3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQT3" } ], "pmid": "" }, { "name": "endoplasmic reticulum tubular network formation", "id": "GO:0071787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071787", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQT3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQT3" } ], "pmid": "" }, { "name": "endoplasmic reticulum tubular network membrane organization", "id": "GO:1990809", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990809", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQT3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQT3" } ], "pmid": "" }, { "name": "positive regulation of epithelial cell migration", "id": "GO:0010634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQT3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQT3" } ], "pmid": "" }, { "name": "positive regulation of toll-like receptor 9 signaling pathway", "id": "GO:0034165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034165", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQT3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQT3" } ], "pmid": "" }, { "name": "positive regulation of ERBB3 signaling pathway", "id": "GO:1905580", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905580", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQT3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQT3" } ], "pmid": "" }, { "name": "positive regulation of protein localization to endoplasmic reticulum", "id": "GO:1905552", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905552", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQT3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQT3" } ], "pmid": "" }, { "name": "nuclear pore complex assembly", "id": "GO:0051292", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051292", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQT3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQT3" } ], "pmid": "" }, { "name": "negative regulation of axon extension", "id": "GO:0030517", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030517", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQT3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQT3" } ], "pmid": "" }, { "name": "protein localization to lysosome", "id": "GO:0061462", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061462", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQT3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQT3" } ], "pmid": "" }, { "name": "intracellular sphingolipid homeostasis", "id": "GO:0090156", "url": 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"MQKRLTQHMKTHSTEKPHMCDKCGKSFKKRYTFKMHLLTHIQAIANRRFKCEFCDYVCEDKKVLLNHQLSHMSDKPYKCSFCKYSTFREDFLVSHMAVKHTGGKPFACEFCHFTTKHKKNLRLHVHCRHADSFEEWAQRHPEEPPCRRRPFFTLQQIEELKQQHRQVQTPAEPEASPAAPLGPVTYQAVQAVPGSEPPILSQDSLEGATIIYEQGVDGSAELATQTALDLLLNMSTQRELAAGSLQVAVVKPDDSGEVQASCEAQAQEEGTELDSSEQQQQKLVTLHMADRGETLVQEAYEEAALGGSELQQITIPFGGTTEYSIITPISEEIPAPGTLYSEEEGSAETSHAVVVSEAVMTEVLKDHNNHYIMSSSVPGNQFQHMEPLNGDAAFPLPAEGQEAQPTGVKWPLVQCVTRQLQKDSNLSPTSEGQEVTSPKVKWPAIQGMAKKLSCKVSTAKKLSCKISTAKKFSCKICTAMFTGRAEMESHKRAHIGPSTFKCPDCPFTAALWPEVRSHMVQHASLRPHKCTHCSFASKNKKDLRRHMLTHTNEKPFACQICGQRFNRNGHLKFHMQRLHSSKGKKPEAPAAPAQQTIILNSDEDTLATLQTALQSGQAVLAPERLQQALGQEHIIVAQEQSIASQEEATYIQEITTADGQTVQHLVTSDNQVQYIIAQDGVQHLLPHEYVVVPEGHHIQDGQITHIQYEQGSQFLQEPQIQYMPVSPEQQLVTQAQLEAAAHSAVSAVADAAMAQAQSVFATEATAEQIQQLQQGIHYDVITLAD", "length": 785, "header": "tr|A0A8V0YQU7-1|A0A8V0YQY5_CHICK Computationally mapped isoform of Zinc finger protein 335 OS=Gallus gallus OX=9031 GN=ZNF335 PE=4 SV=1 CANONICAL=A0A8V0YQY5-1" }, "locus": { "chromosome": "20", "start_pos": 10903459, "end_pos": 10898582, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010036232.1", "url": "https://www.ensembl.org/id/ENSGALT00010036232.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021063.1", "url": "https://www.ensembl.org/id/ENSGALP00010021063.1" } ] } }, { "isoform_ac": "A0A8V0YQY5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQY5/entry#A0A8V0YQY5-1", "sequence": { "sequence": 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"length": 1378, "header": "tr|A0A8V0YQY5-1|A0A8V0YQY5_CHICK Isoform 1 of Zinc finger protein 335 OS=Gallus gallus OX=9031 GN=ZNF335 PE=4 SV=1 CANONICAL=A0A8V0YQY5-1" }, "locus": { "chromosome": "20", "start_pos": 10907017, "end_pos": 10898582, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010036237.1", "url": "https://www.ensembl.org/id/ENSGALT00010036237.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021065.1", "url": "https://www.ensembl.org/id/ENSGALP00010021065.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 211, "start_aa": "Thr", "end_pos": 211, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr211", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 398, "start_aa": "Thr", "end_pos": 398, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr398", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQY5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQY5" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQY5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQY5" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQY5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQY5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQY5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQY5" } ], "pmid": "" }, { "name": "histone methyltransferase complex", "id": "GO:0035097", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035097", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQY5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQY5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 7, "go_terms": [ { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQY5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQY5" } ], "pmid": "" }, { "name": "neuron projection morphogenesis", "id": "GO:0048812", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048812", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQY5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQY5" } ], "pmid": "" }, { "name": "brain development", "id": "GO:0007420", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007420", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQY5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQY5" } ], "pmid": "" }, { "name": "epigenetic regulation of gene expression", "id": "GO:0040029", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0040029", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQY5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQY5" } ], "pmid": "" }, { "name": "positive regulation of neuroblast proliferation", "id": "GO:0002052", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002052", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQY5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQY5" } ], "pmid": "" }, { "name": "positive regulation of neurogenesis", "id": "GO:0050769", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050769", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQY5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQY5" } ], "pmid": "" }, { "name": "positive regulation of lymphocyte proliferation", "id": "GO:0050671", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050671", 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This record is derived from a genomic sequence (NC_052535.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_046796828", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046796828" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQV6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQV6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "KLKB1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQV6", "locus": {} } ], "crossref": [ { "id": "A0A8V0YQV6", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YQV6", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00190", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00190", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd01100", 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This record is derived from a genomic sequence (NC_052544.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process On Mar 1, 2022 this sequence version replaced XP_015149385.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015149385", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015149385" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQX1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQX1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "FNDC9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQX1", "locus": { "chromosome": "13", "start_pos": 10990518, "end_pos": 10987465, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010015074", "url": "https://www.ensembl.org/id/ENSGALG00010015074" } ] } } ], "crossref": [ { "id": "A0A8V0YQX1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YQX1", "database": "AlphaFoldDB", "categories": [] }, { "id": "100857510", "url": "https://www.ncbi.nlm.nih.gov/gene/100857510", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003961", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003961", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036116", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036116", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "TVSWAMS", "url": "https://omabrowser.org/oma/group/TVSWAMS/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YQX1", "url": "https://www.orthodb.org/?gene=A0A8V0YQX1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR37361", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR37361", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR37361:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR37361:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00041", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00041", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF28127", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF28127", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015149385", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015149385", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YQX1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQX1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQX1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQX1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNIEVHNITYTTATVSWTTTNPCPENYYHVMYRPNWNSVFAGYLRQNFHREERVPHSLSSIILHHLTPSTIYVLCITCKNSYPSSNHCTTFHTLDQSPLLFSSSKHETTTSMWMVSSLLLLCFIALLVYGCLQFWAAHCCGTSRPKQPNASPEEVGEGSSSLDGPLSDGLKEELLEVPMTTVLMRSSSFMRESPYSSPRCFFPYKNSDDKTAILPQHNLQ", "length": 220, "header": "tr|A0A8V0YQX1-1|A0A8V0YQX1_CHICK Isoform 1 of Fibronectin type III domain containing 9 OS=Gallus gallus OX=9031 GN=FNDC9 PE=4 SV=1 CANONICAL=A0A8V0YQX1-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YQX1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQX1/entry#A0A8V0YQX1-1", "sequence": { "sequence": "MNIEVHNITYTTATVSWTTTNPCPENYYHVMYRPNWNSVFAGYLRQNFHREERVPHSLSSIILHHLTPSTIYVLCITCKNSYPSSNHCTTFHTLDQSPLLFSSSKHETTTSMWMVSSLLLLCFIALLVYGCLQFWAAHCCGTSRPKQPNASPEEVGEGSSSLDGPLSDGLKEELLEVPMTTVLMRSSSFMRESPYSSPRCFFPYKNSDDKTAILPQHNLQ", "length": 220, "header": "tr|A0A8V0YQX1-1|A0A8V0YQX1_CHICK Isoform 1 of Fibronectin type III domain containing 9 OS=Gallus gallus OX=9031 GN=FNDC9 PE=4 SV=1 CANONICAL=A0A8V0YQX1-1" }, "locus": { "chromosome": "13", "start_pos": 10989727, "end_pos": 10989068, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010036276.1", "url": "https://www.ensembl.org/id/ENSGALT00010036276.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021094.1", "url": "https://www.ensembl.org/id/ENSGALP00010021094.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A4X1TZ26-1", "protein_name": "Fibronectin type III domain containing 9", "gene_name": "FNDC9", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MNIEVGNVSYTGAIISWSSSEPCLEDYYHIMYRPNWNSIFSGYLRYSFHHEEKVPRTISSVVLEHLTPSTLYFLCISCKKILFPYRHYCTMFHTLDKSPLAAGSSLVDPQLSLWVLMAILLACFTAVLAFICLQFWCIRCHEPRWSYRAGHMEEANGLVRWPEDAPALGQGEEDLQGLPLVELPRDNSGAAAEAEGQAPPAAAEADQDAPDMGALQREAGELPANVLPHSGE", "length": 232 }, "evidence": [ { "id": "A0A8V0YQX1", "url": "https://omabrowser.org/oma/group/A0A8V0YQX1/", 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"id": "A0A8V0YXR4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXR4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YXR4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXR4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YXT6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXT6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YXT6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXT6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YZ85", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZ85", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YZ85-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZ85-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z4E0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4E0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z4E0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4E0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z4F0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4F0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z4F0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4F0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z4F5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4F5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z4F5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4F5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z4G8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4G8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z4G8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4G8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKLKKMVFLWHTFVCVPRCLALRLSLLCRLPLSISAACLSVSDGQPVCHKTWGCLVALWPFLVCPVWPTWPELLQIDELPEGAVKPPANKYPIFFFGTHETAFLGPKDLFPYKEYKDKFGKSNKRKGFNEGLWEIENNPGVKFTGYQAIQQQSSSETEGEGGNTADASSEEEGDRVEEDGKGKRKNEKAGSKRKKSYTSKKSSKQSRKSPGDEDDKDCKEEENKSSSDAGDAGNDTRNTSSDLQKTSEGT", "length": 250, "header": "tr|A0A8V0YQX7-1|A0A8V0YQX7_CHICK Isoform 1 of HDGF like 3 OS=Gallus gallus OX=9031 GN=HDGFRP3 PE=1 SV=1 CANONICAL=A0A8V0YQX7-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YQX7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQX7/entry#A0A8V0YQX7-1", "sequence": { "sequence": "MKLKKMVFLWHTFVCVPRCLALRLSLLCRLPLSISAACLSVSDGQPVCHKTWGCLVALWPFLVCPVWPTWPELLQIDELPEGAVKPPANKYPIFFFGTHETAFLGPKDLFPYKEYKDKFGKSNKRKGFNEGLWEIENNPGVKFTGYQAIQQQSSSETEGEGGNTADASSEEEGDRVEEDGKGKRKNEKAGSKRKKSYTSKKSSKQSRKSPGDEDDKDCKEEENKSSSDAGDAGNDTRNTSSDLQKTSEGT", "length": 250, "header": "tr|A0A8V0YQX7-1|A0A8V0YQX7_CHICK Isoform 1 of HDGF like 3 OS=Gallus gallus OX=9031 GN=HDGFRP3 PE=1 SV=1 CANONICAL=A0A8V0YQX7-1" }, "locus": { "chromosome": "10", "start_pos": 11279321, "end_pos": 11259897, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010040371.1", "url": "https://www.ensembl.org/id/ENSGALT00010040371.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023418.1", "url": "https://www.ensembl.org/id/ENSGALP00010023418.1" } ] } }, { "isoform_ac": "A0A8V0YXB2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQX7/entry#A0A8V0YXB2-1", "sequence": { "sequence": "CYLCSLAAPTANKTGPGGGRLAVPRGPGGCDLPCAQAGTLLQQIDELPEGAVKPPANKYPIFFFGTHETAFLGPKDLFPYKEYKDKFGKSNKRKGFNEGLWEIENNPGVKFTGYQAIQQQSSSETEGEGGNTADASSEEEGDRVEEDGKGKRKNEKAGSKRKKSYTSKKSSKQSRKSPGDEDDKDCKEEENKSSSDAGDAGNDTRNTSSDLQKTSEGHLHGCQLRVTPENHELQ", "length": 234, "header": "tr|A0A8V0YXB2-1|A0A8V0YXB2_CHICK Computationally mapped isoform of HDGF like 3 OS=Gallus gallus OX=9031 GN=HDGFRP3 PE=1 SV=1 CANONICAL=A0A8V0YQX7-1" }, "locus": { "chromosome": "10", "start_pos": 11280431, "end_pos": 11266429, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010040367.1", "url": "https://www.ensembl.org/id/ENSGALT00010040367.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023415.1", "url": "https://www.ensembl.org/id/ENSGALP00010023415.1" } ] } }, { "isoform_ac": "A0A8V0YXD8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQX7/entry#A0A8V0YXD8-1", "sequence": { "sequence": "APRRQPAPCTGGCWGCVQGLPLPRVHTHTHTHTHTHTHTLTLTHTPIFFFGTHETAFLGPKDLFPYKEYKDKFGKSNKRKGFNEGLWEIENNPGVKFTGYQAIQQQSSSETEGEGGNTADASSEEEGDRVEEDGKGKRKNEKAGSKRKKSYTSKKSSKQSRKSPGDEDDKDCKEEENKSSSDAGDAGNDTRNTSSDLQKTSEGT", "length": 204, "header": "tr|A0A8V0YXD8-1|A0A8V0YXD8_CHICK Computationally mapped isoform of HDGF like 3 OS=Gallus gallus OX=9031 GN=HDGFRP3 PE=1 SV=1 CANONICAL=A0A8V0YQX7-1" }, "locus": { "chromosome": "10", "start_pos": 11293953, "end_pos": 11259897, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010040408.1", "url": "https://www.ensembl.org/id/ENSGALT00010040408.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023445.1", "url": "https://www.ensembl.org/id/ENSGALP00010023445.1" } ] } }, { "isoform_ac": "A0A8V0YXR4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQX7/entry#A0A8V0YXR4-1", "sequence": { "sequence": "AVHQTPQIIPFVWSPDQVTHICLHSQIDELPEGAVKPPANKYPIFFFGTHETAFLGPKDLFPYKEYKDKFGKSNKRKGFNEGLWEIENNPGVKFTGYQAIQQQSSSETEGEGGNTADASSEEEGDRVEEDGKGKRKNEKAGSKRKKSYTSKKSSKQSRKSPGDEDDKDCKEEENKSSSDAGDAGNDTRNTSSDLQKTSEGT", "length": 201, "header": "tr|A0A8V0YXR4-1|A0A8V0YXR4_CHICK Computationally mapped isoform of HDGF like 3 OS=Gallus gallus OX=9031 GN=HDGFRP3 PE=1 SV=1 CANONICAL=A0A8V0YQX7-1" }, "locus": { "chromosome": "10", "start_pos": 11283559, "end_pos": 11259897, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010040384.1", "url": "https://www.ensembl.org/id/ENSGALT00010040384.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023427.1", "url": "https://www.ensembl.org/id/ENSGALP00010023427.1" } ] } }, { "isoform_ac": "A0A8V0YXT6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQX7/entry#A0A8V0YXT6-1", "sequence": { "sequence": "LERRRQRCTLQSSHSIHLSTRFLRIQIDELPEGAVKPPANKYPIFFFGTHETAFLGPKDLFPYKEYKDKFGKSNKRKGFNEGLWEIENNPGVKFTGYQAIQQQSSSETEGEGGNTADASSEEEGDRVEEDGKGKRKNEKAGSKRKKSYTSKKSSKQSRKSPGDEDDKDCKEEENKSSSDAGDAGNDTRNTSSDLQKTSEGT", "length": 201, "header": "tr|A0A8V0YXT6-1|A0A8V0YXT6_CHICK Computationally mapped isoform of HDGF like 3 OS=Gallus gallus OX=9031 GN=HDGFRP3 PE=1 SV=1 CANONICAL=A0A8V0YQX7-1" }, "locus": { "chromosome": "10", "start_pos": 11315843, "end_pos": 11259897, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010040416.1", "url": "https://www.ensembl.org/id/ENSGALT00010040416.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023452.1", "url": "https://www.ensembl.org/id/ENSGALP00010023452.1" } ] } }, { "isoform_ac": "A0A8V0YZ85-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQX7/entry#A0A8V0YZ85-1", "sequence": { "sequence": "ARPRTGGGGPGDARGDGDEACAQIDELPEGAVKPPANKYPIFFFGTHETAFLGPKDLFPYKEYKDKFGKSNKRKGFNEGLWEIENNPGVKFTGYQAIQQQSSSETEGEGGNTADASSEEEGDRVEEDGKGKRKNEKAGSKRKKSYTSKKSSKQSRKSPGDEDDKDCKEEENKSSSDAGDAGNDTRNTSSDLQKTSEGT", "length": 198, "header": "tr|A0A8V0YZ85-1|A0A8V0YZ85_CHICK Computationally mapped isoform of HDGF like 3 OS=Gallus gallus OX=9031 GN=HDGFRP3 PE=1 SV=1 CANONICAL=A0A8V0YQX7-1" }, "locus": { "chromosome": "10", "start_pos": 11293132, "end_pos": 11259897, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010040390.1", "url": "https://www.ensembl.org/id/ENSGALT00010040390.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023431.1", "url": "https://www.ensembl.org/id/ENSGALP00010023431.1" } ] } }, { "isoform_ac": "A0A8V0Z4E0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQX7/entry#A0A8V0Z4E0-1", "sequence": { "sequence": "CYLCSLAAPTANKTGPGGGRLAVPRGPGGCDLPCAQAGTLLQQIDELPEGAVKPPANKYPIFFFGTHETAFLGPKDLFPYKEYKDKFGKSNKRKGFNEGLWEIENNPGVKFTGYQAIQQQSSSETEGEGGNTADASSEEEGDRVEEDGKGKRKNEKAGSKRKKSYTSKKSSKQSRKSPGDEDDKDCKEEENKSSSDAGDAGNDTRNTSSDLQKTSEGT", "length": 218, "header": "tr|A0A8V0Z4E0-1|A0A8V0Z4E0_CHICK Computationally mapped isoform of HDGF like 3 OS=Gallus gallus OX=9031 GN=HDGFRP3 PE=1 SV=1 CANONICAL=A0A8V0YQX7-1" }, "locus": { "chromosome": "10", "start_pos": 11280431, "end_pos": 11259897, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010040378.1", "url": "https://www.ensembl.org/id/ENSGALT00010040378.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023424.1", "url": "https://www.ensembl.org/id/ENSGALP00010023424.1" } ] } }, { "isoform_ac": "A0A8V0Z4F0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQX7/entry#A0A8V0Z4F0-1", "sequence": { "sequence": "MARPRPREYKAGDLVFAKMKGYPHWPARIDELPEGAVKPPANKYPIFFFGTHETAFLGPKDLFPYKEYKDKFGKSNKRKGFNEGLWEIENNPGVKFTGYQQQSSSETEGEGGNTADASSEEEGDRVEEDGKGKRKNEKAGSKRKKSYTSKKSSKQSRKSPGDEDDKDCKEEENKSSSDAGDAGNDTRNTSSDLQKTSEGT", "length": 200, "header": "tr|A0A8V0Z4F0-1|A0A8V0Z4F0_CHICK Computationally mapped isoform of HDGF like 3 OS=Gallus gallus OX=9031 GN=HDGFRP3 PE=1 SV=1 CANONICAL=A0A8V0YQX7-1" }, "locus": { "chromosome": "10", "start_pos": 11293619, "end_pos": 11259897, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010040394.1", "url": "https://www.ensembl.org/id/ENSGALT00010040394.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023434.1", "url": "https://www.ensembl.org/id/ENSGALP00010023434.1" } ] } }, { "isoform_ac": "A0A8V0Z4F5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQX7/entry#A0A8V0Z4F5-1", "sequence": { "sequence": "MARPRPREYKAGDLVFAKMKGYPHWPARIDELPEGAVKPPANKYPIFFFGTHETAFLGPKDLFPYKEYKDKFGKSNKRKGFNEGLWEIENNPGVKFTGYQAIQQQSSSETEGEGGNTADASSEEEGDRVEEDGKGKRKNEKAGSKRKKSYTSKKSSKQSRKSPGDEDDKDCKEEENKSSSDAGDAGNDTRNTSSDLQKTSEGT", "length": 203, "header": "tr|A0A8V0Z4F5-1|A0A8V0Z4F5_CHICK Computationally mapped isoform of HDGF like 3 OS=Gallus gallus OX=9031 GN=HDGFRP3 PE=1 SV=1 CANONICAL=A0A8V0YQX7-1" }, "locus": { "chromosome": "10", "start_pos": 11293619, "end_pos": 11259897, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010040402.1", "url": "https://www.ensembl.org/id/ENSGALT00010040402.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023439.1", "url": "https://www.ensembl.org/id/ENSGALP00010023439.1" } ] } }, { "isoform_ac": "A0A8V0Z4G8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQX7/entry#A0A8V0Z4G8-1", "sequence": { "sequence": "SADFSPAPREEEEEIDELPEGAVKPPANKYPIFFFGTHETAFLGPKDLFPYKEYKDKFGKSNKRKGFNEGLWEIENNPGVKFTGYQAIQQQSSSETEGEGGNTADASSEEEGDRVEEDGKGKRKNEKAGSKRKKSYTSKKSSKQSRKSPGDEDDKDCKEEENKSSSDAGDAGNDTRNTSSDLQKTSEGT", "length": 189, "header": "tr|A0A8V0Z4G8-1|A0A8V0Z4G8_CHICK Computationally mapped isoform of HDGF like 3 OS=Gallus gallus OX=9031 GN=HDGFRP3 PE=1 SV=1 CANONICAL=A0A8V0YQX7-1" }, "locus": { "chromosome": "10", "start_pos": 11293357, "end_pos": 11259897, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010040413.1", "url": "https://www.ensembl.org/id/ENSGALT00010040413.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023449.1", "url": "https://www.ensembl.org/id/ENSGALP00010023449.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 69, "start_aa": "Thr", "end_pos": 69, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr69", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:415463", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:415463", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287AQQ1-1", "protein_name": "HDGF like 3", "gene_name": "HDGFL3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAVREPAAVRGGKSWKGVVVIQSQQEPSWPSFIHLPVHPSPIDELPEGAVKPPANKYPIFFFGTHETAFLGPKDLFPYKEYKDKFGKSNKRKGFNEGLWEIENNPGVKFTGYQAIQQQSSSETEGEGGNTADASSEEEGDRVEEDGKGKRKNEKAGSKRKKSYTSKKSSKQSRKSPGDEDDKDCKEEENKSSSEGGDAGNDTRNTTSDLQKTSEGT", "length": 216 }, "evidence": [ { "id": "A0A8V0YQX7", "url": "https://omabrowser.org/oma/group/A0A8V0YQX7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0AAA9TTJ4-1", "protein_name": "HDGF like 3", "gene_name": "HDGFL3", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "SYGDPSSNPDCPARRIRKPSVTSVKWLALGGSHRIVKSRPRIDELPEGAVKPPANKYPIFFFGTHETAFLGPKDLFPYKEYKDKFGKSNKRKGFNEGLWEIENNPGVKFTGYQAIQQQSSSETEGEGGNTADASSEEEGDRVEEDGKGKRKSEKAGSKRKKSYTSKKSSKQSRKSPGDEDDKDCKEEENKSSSEGGDAGNDTRNTTSDLQKTSEGT", "length": 216 }, "evidence": [ { "id": "A0A8V0YQX7", "url": "https://omabrowser.org/oma/group/A0A8V0YQX7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q923W4-1", "protein_name": "Hepatoma-derived growth factor-related protein 3", "gene_name": "Hdgfl3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MARPRPREYKAGDLVFAKMKGYPHWPARIDELPEGAVKPPANKYPIFFFGTHETAFLGPKDLFPYKEYKDKFGKSNKRKGFNEGLWEIENNPGVKFTGYQTIQQQSSSETEGEGGNTADASSEEEGDRVEDGKGKRKNEKGGSKRKKSYTSKKSSKQSRKSPGDEDDKDCKEEENKSSSEGGDAGNDTRNTTSDLQKAGEGT", "length": 202 }, "evidence": [ { "id": "A0A8V0YQX7", "url": "https://omabrowser.org/oma/group/A0A8V0YQX7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9JMG7-1", "protein_name": "Hepatoma-derived growth factor-related protein 3", "gene_name": "Hdgfl3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MARPRPREYKAGDLVFAKMKGYPHWPARIDELPEGAVKPPANKYPIFFFGTHETAFLGPKDLFPYKEYKDKFGKSNKRKGFNEGLWEIENNPGVKFTGYQTIQQQSSSETEGEGGNTADASSEEEGDRVEDGKGKRKNEKGGSKRKKSYTSKKSSKQSRKSPGDEDDKDCKEEENKSSSEGGDAGNDTRNTTADLQKAGEGT", "length": 202 }, "evidence": [ { "id": "A0A8V0YQX7", "url": "https://omabrowser.org/oma/group/A0A8V0YQX7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9Y3E1-1", "protein_name": "Hepatoma-derived growth factor-related protein 3", "gene_name": "HDGFL3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MARPRPREYKAGDLVFAKMKGYPHWPARIDELPEGAVKPPANKYPIFFFGTHETAFLGPKDLFPYKEYKDKFGKSNKRKGFNEGLWEIENNPGVKFTGYQAIQQQSSSETEGEGGNTADASSEEEGDRVEEDGKGKRKNEKAGSKRKKSYTSKKSSKQSRKSPGDEDDKDCKEEENKSSSEGGDAGNDTRNTTSDLQKTSEGT", "length": 203 }, "evidence": [ { "id": "A0A8V0YQX7", "url": "https://omabrowser.org/oma/group/A0A8V0YQX7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "microtubule polymerization", "id": "GO:0046785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046785", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQX7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQX7" } ], "pmid": "" }, { "name": "neuron projection development", "id": "GO:0031175", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031175", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQX7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQX7" } ], "pmid": "" }, { "name": "negative regulation of microtubule depolymerization", "id": "GO:0007026", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007026", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQX7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQX7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQX7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQX7" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQX7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQX7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "microtubule binding", "id": "GO:0008017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008017", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YQX7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQX7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 223, "end_pos": 225, "annotation": "n_glycosylation_sequon" }, { "start_pos": 234, "end_pos": 236, "annotation": "n_glycosylation_sequon" }, { "start_pos": 238, "end_pos": 240, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YQX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQX7" }, { "id": "PF00855", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00855" } ], "ann_type": 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"NUDT16L1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQZ5", "locus": { "chromosome": "14", "start_pos": 12351849, "end_pos": 12354617, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010016756", "url": "https://www.ensembl.org/id/ENSGALG00010016756" } ] } } ], "crossref": [ { "id": "A0A8V0YQZ5", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YQZ5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000039779", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000039779", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd18869", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18869", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "395557", "url": "https://www.ncbi.nlm.nih.gov/gene/395557", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR015797", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015797", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR054754", "url": "https://www.ebi.ac.uk/interpro/entry/IPR054754", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A1L1RIX9", "url": "https://www.orthodb.org/?gene=A0A1L1RIX9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YQZ5", "url": "https://www.orthodb.org/?gene=A0A8V0YQZ5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31699", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31699", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31699:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31699:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF22327", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22327", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A1L1RIX9", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RIX9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1L1RIX9-1", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RIX9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQZ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQZ5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQZ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQZ5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAMGAMGVMAAVGALPAGAGSLPPLPTLGVPGVPELKPLTRYEAMRLGPGWSHSCHAMLYAPNPGMLFGRIPLRYAVLMQMRFDGLLGFPGGFVDRRYWSLEDGLNRVLGLGLGCVRLTEADYLCSHLTDGPHRVVAHLYARQLTLEELHTIEISAVHSRDHGLEVMGMVRVPLYTQKDRMGGLPNFLANSFVGTAKFQLLFALKILNMVPEEKLAEAVAATQKPKKPAIDHAAVAAAKQANELAAAGLESQAVLEHLAAVPGAEAVVAELHAQPGADAVLEQPVAEAME", "length": 291, "header": "tr|A0A8V0YQZ5-1|A0A8V0YQZ5_CHICK Isoform 1 of Tudor-interacting repair regulator protein OS=Gallus gallus OX=9031 GN=NUDT16L1 PE=1 SV=1 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"url": "https://www.ncbi.nlm.nih.gov/protein/XP_004936472" }, "gene_names": [ { "name": "CLBA1", "type": "recommended", "evidence": [ { "id": "A0A8V0YR39", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YR39" } ] }, { "name": "CLBA1", "type": "synonym", "evidence": [ { "id": "XP_004936472", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004936472" } ] } ], "protein_names": [ { "name": "Clathrin binding box of aftiphilin containing 1", "type": "synonym", "evidence": [ { "id": "A0A8V0YR39", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YR39/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein CLBA1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_004936472", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004936472" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052536.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_004936472.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004936472", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004936472" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YR39", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YR39" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CLBA1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YR39", "locus": { "chromosome": "5", "start_pos": 51438012, "end_pos": 51426891, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010016783", "url": "https://www.ensembl.org/id/ENSGALG00010016783" } ] } } ], "crossref": [ { "id": "A0A8V0YR39", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YR39", "database": "AlphaFoldDB", "categories": [] }, { "id": "423498", 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"field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YR44-1", "uniprot_ac": "A0A8V0YR44", "uniprot_id": "A0A8V0YR44_CHICK", "mass": { "chemical_mass": 159556.0, "monoisotopic_mass": 159556.0 }, "refseq": {}, "gene_names": [ { "name": "AIM1L", "type": "recommended", "evidence": [ { "id": "A0A8V0YR44", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YR44" } ] } ], "protein_names": [ { "name": "Crystallin beta-gamma domain containing 2", "type": "synonym", "evidence": [ { "id": "A0A8V0YR44", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YR44/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YR44", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YR44" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "AIM1L", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YR44", "locus": {} } ], "crossref": [ { "id": "cd23465", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd23465", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "419544", "url": "https://www.ncbi.nlm.nih.gov/gene/419544", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000772", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000772", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001064", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001064", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035992", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035992", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050252", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050252", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:419544", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419544", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HRESYMH", "url": "https://omabrowser.org/oma/group/HRESYMH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YR44", "url": "https://www.orthodb.org/?gene=A0A8V0YR44", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YXJ8", "url": "https://www.orthodb.org/?gene=A0A8V0YXJ8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YXX8", "url": "https://www.orthodb.org/?gene=A0A8V0YXX8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z4K1", "url": "https://www.orthodb.org/?gene=A0A8V0Z4K1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11818", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11818", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11818:SF50", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11818:SF50", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00030", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00030", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00652", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00652", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YR44", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YR44", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YR44-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YR44-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YXJ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXJ8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YXJ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXJ8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YXX8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXX8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YXX8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXX8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z4K1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4K1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z4K1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4K1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEGTTKVQRDGLKVWGLSSAGFLVPLLAAPPALLRGGGGRMDLPFQHSVAKGCVSSAELSMKQTAAPRPESRSRFQKVSLVSRRLEHTAGGGGRDGSPSRVSLLLQAWEREIVEKTAPGPSTVTQRSCSSSVSILKDFAAHGPIFSQVFSPRRREEKREDDTVPAPRDVPVHRESYMHGMLLPTAPRCQRSTRDPKPRARHVTVLRESREAEEGRKTQNGVCKATTVPSSHQKGCKPDASGITKITARGKSSLNTLDTRESSREKCSTPDESHQKGCKLDASGITKITARGKSSLNTLDTRESSREKCSVPDESMPSATPRGRDKPQDPQTSTASAQCPLADQSGVREGGAVHRDGSISATQPRTESSEEAGGTSKNITIEASNGTEPLPDARASPKDAEVEMEEGEMVENHQGVAQDTQSIPEPPMESTEEPQPESIAKPQPESIPKPQPESVPKLQSEGVPKPQPESVLKPQPEGVPKPQPEGVPKPQPESTPKHQSESVPEPQSKSISKPQTENIPEPPHESPAPPSESPPDASEEDPELVVDMEIFVDTLRNMEPSEIRKAPKVPRQPRPSVLGRCTALPPIHEDRVAPRAHISLPVALQELLAWGGGGQRAETPPQGTESHDEEEEIENPYLSPEEKALRRAQNGNGELGSLLGGAMQGRATGERSILFRGNVLKGMALLSDFLEHRSAAVDEAKPYSRLDNSMLYSRFVSPASIHNGVPNGTGASDHPSTELEAVSPDHIPPVPEEPESVGAPYHTDIPQEDKEGSLKINTRPGKIILFSEAGFAGHRREIWGDVPDATSWELSHKISIRVIRGGWVMYEKPRFHGRKCVLAEGDVEIDNPWMVYRQSDEPRGSWPFRIGSFKRVVKDYRVPEISLFAEENGEGARLQFSDSAEDTRVQGQSLTASSIIHLGISSLGGWLGEQRIHPSGCPVVERPGEPQVLIYEDMGFQGHSFIISRDIYDLKRLPELLLPTVGSMRVLGGCWVGYEKEGFRGHQYLLEEGEYHDWRQWGGYSKELVSLRLIRTDFSDPALVLFEATDFEEGPSVELSEALPDVQLAGYGTVTQSIHVLSGVWVAYEGPNFSGEQYILEKGVYRNCEDWGATNCCITSAQPILQVREHNLHFVSKVWSGMWGGEHTHLGVTTLCGMVTVWILFDSQAFTGEQHVLSEGEYPTLGAMGCLSSTTIRSLKKVPVFFSEPSIFLHGLECFEGKEIELNNEVRSLQAEGFNNHVLSVRVKGGIWVLCEHGDFRGRQWLLECTEITNWLTYSGLQHVGSLYPIRQRRIYFRIRNKELQLYLSVPDDVEDMKAGRVVVSSLSEQSNSVWYYEDGLLKNQVAPTMSLQVIGPAGKGAKAVLWSETRMPRQTWSIDSQGRIHSQMFEDMILDVKGEAVVPAQGLLSQGPHGHGVLDGDALLFAGGRSYDRDHAIICEVAEERPTQIWDVQVL", "length": 1451, "header": "tr|A0A8V0YR44-1|A0A8V0YR44_CHICK Isoform 1 of Crystallin beta-gamma domain containing 2 OS=Gallus gallus OX=9031 GN=AIM1L PE=3 SV=1 CANONICAL=A0A8V0YR44-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YR44-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YR44/entry#A0A8V0YR44-1", "sequence": { "sequence": "MEGTTKVQRDGLKVWGLSSAGFLVPLLAAPPALLRGGGGRMDLPFQHSVAKGCVSSAELSMKQTAAPRPESRSRFQKVSLVSRRLEHTAGGGGRDGSPSRVSLLLQAWEREIVEKTAPGPSTVTQRSCSSSVSILKDFAAHGPIFSQVFSPRRREEKREDDTVPAPRDVPVHRESYMHGMLLPTAPRCQRSTRDPKPRARHVTVLRESREAEEGRKTQNGVCKATTVPSSHQKGCKPDASGITKITARGKSSLNTLDTRESSREKCSTPDESHQKGCKLDASGITKITARGKSSLNTLDTRESSREKCSVPDESMPSATPRGRDKPQDPQTSTASAQCPLADQSGVREGGAVHRDGSISATQPRTESSEEAGGTSKNITIEASNGTEPLPDARASPKDAEVEMEEGEMVENHQGVAQDTQSIPEPPMESTEEPQPESIAKPQPESIPKPQPESVPKLQSEGVPKPQPESVLKPQPEGVPKPQPEGVPKPQPESTPKHQSESVPEPQSKSISKPQTENIPEPPHESPAPPSESPPDASEEDPELVVDMEIFVDTLRNMEPSEIRKAPKVPRQPRPSVLGRCTALPPIHEDRVAPRAHISLPVALQELLAWGGGGQRAETPPQGTESHDEEEEIENPYLSPEEKALRRAQNGNGELGSLLGGAMQGRATGERSILFRGNVLKGMALLSDFLEHRSAAVDEAKPYSRLDNSMLYSRFVSPASIHNGVPNGTGASDHPSTELEAVSPDHIPPVPEEPESVGAPYHTDIPQEDKEGSLKINTRPGKIILFSEAGFAGHRREIWGDVPDATSWELSHKISIRVIRGGWVMYEKPRFHGRKCVLAEGDVEIDNPWMVYRQSDEPRGSWPFRIGSFKRVVKDYRVPEISLFAEENGEGARLQFSDSAEDTRVQGQSLTASSIIHLGISSLGGWLGEQRIHPSGCPVVERPGEPQVLIYEDMGFQGHSFIISRDIYDLKRLPELLLPTVGSMRVLGGCWVGYEKEGFRGHQYLLEEGEYHDWRQWGGYSKELVSLRLIRTDFSDPALVLFEATDFEEGPSVELSEALPDVQLAGYGTVTQSIHVLSGVWVAYEGPNFSGEQYILEKGVYRNCEDWGATNCCITSAQPILQVREHNLHFVSKVWSGMWGGEHTHLGVTTLCGMVTVWILFDSQAFTGEQHVLSEGEYPTLGAMGCLSSTTIRSLKKVPVFFSEPSIFLHGLECFEGKEIELNNEVRSLQAEGFNNHVLSVRVKGGIWVLCEHGDFRGRQWLLECTEITNWLTYSGLQHVGSLYPIRQRRIYFRIRNKELQLYLSVPDDVEDMKAGRVVVSSLSEQSNSVWYYEDGLLKNQVAPTMSLQVIGPAGKGAKAVLWSETRMPRQTWSIDSQGRIHSQMFEDMILDVKGEAVVPAQGLLSQGPHGHGVLDGDALLFAGGRSYDRDHAIICEVAEERPTQIWDVQVL", "length": 1451, "header": "tr|A0A8V0YR44-1|A0A8V0YR44_CHICK Isoform 1 of Crystallin beta-gamma domain containing 2 OS=Gallus gallus OX=9031 GN=AIM1L PE=3 SV=1 CANONICAL=A0A8V0YR44-1" }, "locus": { "chromosome": "23", "start_pos": 574980, "end_pos": 567840, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010040479.1", "url": "https://www.ensembl.org/id/ENSGALT00010040479.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023493.1", "url": "https://www.ensembl.org/id/ENSGALP00010023493.1" } ] } }, { "isoform_ac": "A0A8V0YXJ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YR44/entry#A0A8V0YXJ8-1", "sequence": { "sequence": "MDLPFQHSVAKGCVSSAELSMKQTAAPRPESRSRFQKVSLVSRRLEHTAGGGGRDGSPSRVSLLLQAWEREIVEKTAPGPSTVTQRSCSSSVSILKDFAAHGPIFSQVFSPRRREEKREDDTVPAPRDVPVHRESYMHGMLLPTAPRCQRSTRDPKPRARHVTVLRESREAEEGRKTQNGVCKATTVPSSHQKGCKPDASGITKITARGKSSLNTLDTRESSREKCSTPDESHQKGCKLDASGITKITARGKSSLNTLDTRESSREKCSVPDESMPSATPRGRDKPQDPQTSTASAQCPLADQSGVREGGAVHRDGSISATQPRTESSEEAGGTSKNITIEASNGTEPLPDARASPKDAEVEMEEGEMVENHQGVAQDTQSIPEPPMESTEEPQPESIAKPQPESIPKPQPESVPKLQSEGVPKPQPESVLKPQPEGVPKPQPEGVPKPQPESTPKHQSESVPEPQSKSISKPQTENIPEPPHESPAPPSESPPDASEEDPELVVDMEIFVDTLRNMEPSEIRKAPKVPRQPRPSVLGRCTALPPIHEDRVAPRAHISLPVALQELLAWGGGGQRAETPPQGTESHDEEEEIENPYLSPEEKALRRAQNGNGELGSLLGGAMQGRATGERSILFRGNVLKGMALLSDFLEHRSAAVDEAKPYSRLDNSMLYSRFVSPASIHNGVPNGTGASDHPSTELEAVSPDHIPPVPEEPESVGAPYHTDIPQEDKEGSLKINTRPGKIILFSEAGFAGHRREIWGDVPDATSWELSHKISIRVIRGGWVMYEKPRFHGRKCVLAEGDVEIDNPWMVYRQSDEPRGSWPFRIGSFKRVVKDYRVPEISLFAEENGEGARLQFSDSAEDTRVQGQSLTASSIIVHSGLWLVYSKPFFDDDPYVLEPGGYPNLKAWGAKDPSICSMHPIRLGCPVVERPGEPQVLIYEDMGFQGHSFIISRDIYDLKRLPELLLPTVGSMRVLGGCWVGYEKEGFRGHQYLLEEGEYHDWRQWGGYSKELVSLRLIRTDFSDPALVLFEATDFEEGPSVELSEALPDVQLAGYGTVTQSIHVLSGVWVAYEGPNFSGEQYILEKGVYRNCEDWGATNCCITSAQPILQVREHNLHFVSKILLFSEPDFLGEHLAFEDEQNALPDSFVPRSCRVRGGSWILFDSQAFTGEQHVLSEGEYPTLGAMGCLSSTTIRSLKKVPVFFSEPSIFLHGLECFEGKEIELNNEVRSLQAEGFNNHVLSVRVKGGIWVLCEHGDFRGRQWLLECTEITNWLTYSGLQHVGSLYPIRQRRIYFRIRNKELQLYLSVPDDVEDMKAGRVVVSSLSEQSNSVWYYEDGLLKNQVAPTMSLQVIGPAGKGAKAVLWSETRMPRQTWSIDSQGRIHSQMFEDMILDVKGGRSYDRDHAIICEVAEERPTQIWDVQVL", "length": 1424, "header": "tr|A0A8V0YXJ8-1|A0A8V0YXJ8_CHICK Computationally mapped isoform of Crystallin beta-gamma domain containing 2 OS=Gallus gallus OX=9031 GN=AIM1L PE=3 SV=1 CANONICAL=A0A8V0YR44-1" }, "locus": { "chromosome": "23", "start_pos": 574980, "end_pos": 567960, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010040505.1", "url": "https://www.ensembl.org/id/ENSGALT00010040505.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023510.1", "url": "https://www.ensembl.org/id/ENSGALP00010023510.1" } ] } }, { "isoform_ac": "A0A8V0YXX8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YR44/entry#A0A8V0YXX8-1", "sequence": { "sequence": "MEGTTKVQRDGLKVWGLSSAGFLVPLLAAPPALLRGGGGRMDLPFQHSVAKGCVSSAELSMKQTAAPRPESRSRFQKVSLVSRRLEHTAGGGGRDGSPSRVSLLLQAWEREIVEKTAPGPSTVTQRSCSSSVSILKDFAAHGPIFSQVFSPRRREEKREDDTVPAPRDVPVHRESYMHGMLLPTAPRCQRSTRDPKPRARHVTVLRESREAEEGRKTQNGVCKATTVPSSHQKGCKPDASGITKITARGKSSLNTLDTRESSREKCSTPDESHQKGCKLDASGITKITARGKSSLNTLDTRESSREKCSVPDESMPSATPRGRDKPQDPQTSTASAQCPLADQSGVREGGAVHRDGSISATQPRTESSEEAGGTSKNITIEASNGTEPLPDARASPKDAEVEMEEGEMVENHQGVAQDTQSIPEPPMESTEEPQPESIAKPQPESIPKPQPESVPKLQSEGVPKPQPESVLKPQPEGVPKPQPEGVPKPQPESTPKHQSESVPEPQSKSISKPQTENIPEPPHESPAPPSESPPDASEEDPELVVDMEIFVDTLRNMEPSEIRKAPKVPRQPRPSVLGRCTALPPIHEDRVAPRAHISLPVALQELLAWGGGGQRAETPPQGTESHDEEEEIENPYLSPEEKALRRAQNGNGELGSLLGGAMQGRATGERSILFRGNVLKGMALIHNGVPNGTGASDHPSTELEAVSPDHIPPVPEEPESQEDKEGSLKINTRPGKIILFSEAGFAGHRREIWGDVPDATSWELSHKISIRVIRGGWVMYEKPRFHGRKCVLAEGDVEIDNPWMVYRQSDEPRGSWPFRIGCGVLLARGAPSRQRAFGYFLPRWLVYSKPFFDDDPYVLEPGGYPNLKAWGAKDPSICSMHPIRLGCPVVERPGEPQVLIYEDMGFQGHSFIISRDIYDLKRLPELLLPTVGSMRVLGGCWVGYEKEGFRGHQYLLEEGEYHDWRQWGGYSKELVSLRLIRTDFSDPALVLFEATDFEEGPSVELSEALPDVQLAGYGTVTQSIHVLSGVWVAYEGPNFSGEQYILEKGVYRNCEDWGATNCCITSAQPILQVGVHGPPRILLFSEPDFLGEHLAFEDEQNALPDSFVPRSCRVRGGSWILFDSQAFTGEQHVLSEGEYPTLGAMGCLSSTTIRSLKKVPVFFSEPSIFLHGLECFEGKEIELNNEVRSLQAEGFNNHVLSVRVKGGIWVLCEHGDFRGRQWLLECTEITNWLTYSGLQHVGSLYPIRQRRIYFRIRNKELQLYLSVPDDVEDMKAGRVVVSSLSEQSNSVWYYEDGLLKNQVAPTMSLQVIGPAGKGAKAVLWSETRMPRQTWSIDSQGRIHSQMFEDMILDVKGGRSYDRDHAIICEVAEERPTQIWDVQVL", "length": 1384, "header": "tr|A0A8V0YXX8-1|A0A8V0YXX8_CHICK Computationally mapped isoform of Crystallin beta-gamma domain containing 2 OS=Gallus gallus OX=9031 GN=AIM1L PE=3 SV=1 CANONICAL=A0A8V0YR44-1" }, "locus": { "chromosome": "23", "start_pos": 574980, "end_pos": 567840, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010040488.1", "url": "https://www.ensembl.org/id/ENSGALT00010040488.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023497.1", "url": "https://www.ensembl.org/id/ENSGALP00010023497.1" } ] } }, { "isoform_ac": "A0A8V0Z4K1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YR44/entry#A0A8V0Z4K1-1", "sequence": { "sequence": "MQGRATGERSILFRGNVLKGMALLSDFLEHRSAAVDEAKPYSRLDNSMLYSRFVSPASIHNGVPNGTGASDHPSTELEAVSPDHIPPVPEEPESVGAPYHTDIPVSAALQQCVGMLGRIGGIILFSEAGFAGHRREIWGDVPDATSWELSHKISIRVIRGGWVMYEKPRFHGRKCVLAEGDVEIDNPWMVYRQSDEPRGSWPFRIGSFKRVVKDYRVPEISLFAEENGEGARLQFSDSAEDTRVQGHRQRAFGYFLPRWLVYSKPFFDDDPYVLEPGGYPNLKAWGAKDPSICSMHPIRLGCPVVERPGEPQVLIYEDMGFQGHSFIISRDIYDLKRLPELLLPTVGSMRVLGGCWVGYEKEGFRGHQYLLEEGEYHDWRQWGGYSKELVSLRLIRTDFSDPALVLFEATDFEEGPSVELSEALPDVQLAGYGTVTQSIHVLSGVWVAYEGPNFSGEQYILEKGVYRNCEDWGATNCCITSAQPILQVREHNLHFVSKVWSGQAVLGDTHPLRWLHQLKHTPPLPTSWILFDSQAFTGEQHVLSEGEYPTLGAMGCLSSTTIRSLKKVPVFFSEPSIFLHGLECFEGKEIELNNEVRSLQAEGFNNHVLSVRVKGGIWVLCEHGDFRGRQWLLECTEITNWLTYSGLQHVGSLYPIRQRRIYFRIRNKELQLYLSVPDDVEDMKAGRVVVSSLSEQSNSVWYYEDGLLKNQVAPTMSLQVIGPAGKGAKAVLWSETRMPRQTWSIDSQGRIHSQMFEDMILDVKGGRSYDRDHAIICEVAEERPTQIWDVQVL", "length": 793, "header": "tr|A0A8V0Z4K1-1|A0A8V0Z4K1_CHICK Computationally mapped isoform of Crystallin beta-gamma domain containing 2 OS=Gallus gallus OX=9031 GN=AIM1L PE=3 SV=1 CANONICAL=A0A8V0YR44-1" }, "locus": { "chromosome": "23", "start_pos": 574980, "end_pos": 569823, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010040460.1", "url": "https://www.ensembl.org/id/ENSGALT00010040460.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023479.1", "url": "https://www.ensembl.org/id/ENSGALP00010023479.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1344, "start_aa": "Thr", "end_pos": 1344, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1344", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:419544", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419544", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 1087, "end_pos": 1089, "annotation": "n_glycosylation_sequon" }, { "start_pos": 377, "end_pos": 379, "annotation": "n_glycosylation_sequon" }, { "start_pos": 384, "end_pos": 386, "annotation": "n_glycosylation_sequon" }, { "start_pos": 726, "end_pos": 728, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YR44", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YR44" }, { "id": "PS50915", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50915" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Beta/gamma crystallin 'Greek key'", "eco_id": "ECO_0000259", "start_pos": 820, "end_pos": 872, "start_aa": "Gly", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 1344 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1087, "end_pos": 1089 }, { "start_pos": 377, "end_pos": 379 }, { "start_pos": 384, "end_pos": 386 }, { "start_pos": 726, "end_pos": 728 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YR64-1", "uniprot_ac": "A0A8V0YR64", "uniprot_id": "A0A8V0YR64_CHICK", "mass": { "chemical_mass": 123826.0, "monoisotopic_mass": 123826.0 }, "refseq": { "ac": "XP_015137168", "name": "anillin isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015137168" }, "gene_names": [ { "name": "ANLN", "type": "recommended", "evidence": [ { "id": "A0A8V0YR64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YR64" } ] }, { "name": "ANLN", "type": "synonym", "evidence": [ { "id": "XP_015137168", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015137168" } ] } ], "protein_names": [ { "name": "Anillin", "type": "recommended", "evidence": [ { "id": "A0A8V0YR64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YR64/entry#names_and_taxonomy" } ] }, { "name": "anillin isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015137168", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015137168" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052533.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015137168.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015137168", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015137168" } ] }, { "annotation": "Required for cytokinesis. Essential for the structural integrity of the cleavage furrow and for completion of cleavage furrow ingression. Plays a role in bleb assembly during metaphase and anaphase of mitosis. May play a significant role in podocyte cell migration.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YZG2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZG2#function" }, { "database": "UniProtKB", "id": "ARBA00057106", "url": "https://www.uniprot.org/uniprotkb/ARBA00057106#function" }, { "database": "UniProtKB", "id": "A0A8V0Z4M9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4M9#function" }, { "database": "UniProtKB", "id": "A0A8V0YR64", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YR64#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YR64", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YR64" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ANLN", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YR64", "locus": { "chromosome": "2", "start_pos": 46648091, "end_pos": 46677005, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010016788", "url": "https://www.ensembl.org/id/ENSGALG00010016788" } ] } } ], "crossref": [ { "id": "A0A8V0YR64", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YR64", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd01263", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01263", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "420738", "url": "https://www.ncbi.nlm.nih.gov/gene/420738", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001849", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001849", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012966", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012966", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR031970", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031970", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037840", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037840", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051364", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051364", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:420738", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420738", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PKIEQQT", "url": "https://omabrowser.org/oma/group/PKIEQQT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YR64", "url": "https://www.orthodb.org/?gene=A0A8V0YR64", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YZG2", "url": "https://www.orthodb.org/?gene=A0A8V0YZG2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z4M9", "url": "https://www.orthodb.org/?gene=A0A8V0Z4M9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21538", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21538", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21538:SF27", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21538:SF27", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00169", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00169", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08174", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08174", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16018", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16018", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-8980692", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8980692", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9013026", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013026", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9013106", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013106", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_015137168", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015137168", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YR64", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YR64", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YR64-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YR64-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YZG2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZG2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YZG2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZG2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z4M9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4M9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z4M9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4M9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDPFTEKLLERTRARRENLQKKMAERPTMAARLAAQTKRAREPLLETSNQTSLPDGEVKPTKPSPSKRRCSNNKETEASTIENTQPLPSSSPSHRSPVMNSELHGTVCNKASPAQSLEKGKTSTKSETPATLSVKTRMQKLAEQRRCWDSEDPSECARLSPLQSKALSVSPPKQATNDLASGTPIGRRGRLANLAATIGSWEDDLSHPSAKQNNAQEQPGTTCLSKLSTTSGASARINSSSVKQEAASCSQRLVEASINKPANSKIADPNNSITQSSSSTVPASKKSEVPQQITENPCSPQKTEKRTQTVQSTLSQSVQSREETVKGTHVQPEPKDKPTTPGGSGIKSFLERFGERCQENSARSPSTNTPGYRTPIVTPNTRTIQEKLLKQNENSSTATLALQLKQERERELACIRGRFDKGNLWSAERSESSKRKLPEAKMDGPSQGSPKRSPRSDTTTSGSAEDTPAGDRPEESPSVESSDAVKCEETDKSSSLMVTQPKSPVEAMPVSKLEQLAKKPNDEVCEVETKAGDEMNSSKVINEIFEILQEDGPDIEKLKKEMSMSLEGESDDDEQEESLNISSMSLLTPLVESVGPEVFVSPSKSVGEDSSVSDVSQKSDKFQRTKVPRAESGDSMSSLSEDRSLPYSVDAYRSQRFKETDRPSIKQVIVRKEDVASKLEMKKNGPCDQVNIKKKMQELNNEINMQQTVIYQASQALNCCFDEEHGKGSQEEAEAERLLLLATEKRTALLEELNKLKIEGPLVKRSKAASVSSEFSPSRGSVSISEMRLPLKADFVCGTVQKPEAANYYYVIILRSGAENMVATPLASTASSLNGDALTFTTTFTMHDVSNDFEINIEVYSLVQRKEAPSTDKKKKANKSKVITPKRLLTSITSKSTLLTPAMASPGGPNAVRTTNFILVGTHKLSLSSVGHAKFALDKMNFEGEERDLLSYMFRDKVPVLSPLEGHIYLKLKCQVDSSVEEKGFLTMFEDVSGFGAWHRRWCVLSGNCISYWTYPDDEKRKHPLGRINLANCTNRQIEPVNREFCARPNTFELITVRPQREDDKETLVSQCRDTLCVTKNWLSADTKEERNLWMQKLNQVLVDLRMWQPDACYKPIGKL", "length": 1120, "header": "tr|A0A8V0YR64-1|A0A8V0YR64_CHICK Isoform 1 of Anillin OS=Gallus gallus OX=9031 GN=ANLN PE=4 SV=1 CANONICAL=A0A8V0YR64-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YR64-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YR64/entry#A0A8V0YR64-1", "sequence": { "sequence": "MDPFTEKLLERTRARRENLQKKMAERPTMAARLAAQTKRAREPLLETSNQTSLPDGEVKPTKPSPSKRRCSNNKETEASTIENTQPLPSSSPSHRSPVMNSELHGTVCNKASPAQSLEKGKTSTKSETPATLSVKTRMQKLAEQRRCWDSEDPSECARLSPLQSKALSVSPPKQATNDLASGTPIGRRGRLANLAATIGSWEDDLSHPSAKQNNAQEQPGTTCLSKLSTTSGASARINSSSVKQEAASCSQRLVEASINKPANSKIADPNNSITQSSSSTVPASKKSEVPQQITENPCSPQKTEKRTQTVQSTLSQSVQSREETVKGTHVQPEPKDKPTTPGGSGIKSFLERFGERCQENSARSPSTNTPGYRTPIVTPNTRTIQEKLLKQNENSSTATLALQLKQERERELACIRGRFDKGNLWSAERSESSKRKLPEAKMDGPSQGSPKRSPRSDTTTSGSAEDTPAGDRPEESPSVESSDAVKCEETDKSSSLMVTQPKSPVEAMPVSKLEQLAKKPNDEVCEVETKAGDEMNSSKVINEIFEILQEDGPDIEKLKKEMSMSLEGESDDDEQEESLNISSMSLLTPLVESVGPEVFVSPSKSVGEDSSVSDVSQKSDKFQRTKVPRAESGDSMSSLSEDRSLPYSVDAYRSQRFKETDRPSIKQVIVRKEDVASKLEMKKNGPCDQVNIKKKMQELNNEINMQQTVIYQASQALNCCFDEEHGKGSQEEAEAERLLLLATEKRTALLEELNKLKIEGPLVKRSKAASVSSEFSPSRGSVSISEMRLPLKADFVCGTVQKPEAANYYYVIILRSGAENMVATPLASTASSLNGDALTFTTTFTMHDVSNDFEINIEVYSLVQRKEAPSTDKKKKANKSKVITPKRLLTSITSKSTLLTPAMASPGGPNAVRTTNFILVGTHKLSLSSVGHAKFALDKMNFEGEERDLLSYMFRDKVPVLSPLEGHIYLKLKCQVDSSVEEKGFLTMFEDVSGFGAWHRRWCVLSGNCISYWTYPDDEKRKHPLGRINLANCTNRQIEPVNREFCARPNTFELITVRPQREDDKETLVSQCRDTLCVTKNWLSADTKEERNLWMQKLNQVLVDLRMWQPDACYKPIGKL", "length": 1120, "header": "tr|A0A8V0YR64-1|A0A8V0YR64_CHICK Isoform 1 of Anillin OS=Gallus gallus OX=9031 GN=ANLN PE=4 SV=1 CANONICAL=A0A8V0YR64-1" }, "locus": { "chromosome": "2", "start_pos": 46676891, "end_pos": 46649344, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010040508.1", "url": "https://www.ensembl.org/id/ENSGALT00010040508.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023513.1", "url": "https://www.ensembl.org/id/ENSGALP00010023513.1" } ] } }, { "isoform_ac": "A0A8V0YZG2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YR64/entry#A0A8V0YZG2-1", "sequence": { "sequence": "MDPFTEKLLERTRARRENLQKKMAERPTMAARLAAQTKRAREPLLETSNQTSLPDGEVKPTKPSPSKRRCSNNKETEASTIENTQPLPSSSPSHRSPVMNSELHGTVCNKASPAQSLEKGKTSTKSETPATLSVKTRMQKLAEQRRCWDSEDPSECARLSPLQSKALSVSPPKQATNDLASGTPIGRRGRLANLAATIGSWEDDLSHPSAKQNNAQEQPGTTCLSKLSTTSGASARINSSSVKQEAASCSQRLVEASINKPANSKIADPNNSITQSSSSTVPASKKSEVPQQITENPCSPQKTEKRTQTVQSTLSQSVQSREETVKGTHVQPEPKDKPTTPGGSGIKSFLERFGERCQENSARSPSTNTPGYRTPIVTPNTRTIQEKLLKQNENSSTATLALQLKQERERELACIRGRFDKGNLWSAERSESSKRKLPEAKMDGPSQGSPKRSPRSDTTTSGSAEDTPAGDRPEESPSVESSDEVCEVETKAGDEMNSSKVINEIFEILQEDGPDIEKLKKEMSMSLEGESDDDEQEESLNISSMSLLTPLVESVGPEVFVSPSKSVGEDSSVSDVSQKSDKFQRTKVPRAESGDSMSSLSEDRSLPYSVDAYRSQRFKETDRPSIKQVIVRKEDVASKLEMKKNGPCDQVNIKKKMQELNNEINMQQTVIYQASQALNCCFDEEHGKGSQEEAEAERLLLLATEKRTALLEELNKLKIEGPLVKRSKAASVSSEFSPSRGSVSISEMRLPLKADFVCGTVQKPEAANYYYVIILRSGAENMVATPLASTASSLNGDALTFTTTFTMHDVSNDFEINIEVYSLVQRKEAPSTDKKKKANKSKVITPKRLLTSITSKSTLLTPAMASPGGPNAVRTTNFILVGTHKLSLSSVGHAKFALDKMNFEGEERDLLSYMFRDKVPVLSPLEGHIYLKLKCQVDSSVEEKGFLTMFEDVSGFGAWHRRWCVLSGNCISYWTYPDDEKRKHPLGRINLANCTNRQIEPVNREFCARPNTFELITVRPQREDDKETLVSQCRDTLCVTKNWLSADTKEERNLWMQKLNQVLVDLRMWQPDACYKPIGKL", "length": 1081, "header": "tr|A0A8V0YZG2-1|A0A8V0YZG2_CHICK Computationally mapped isoform of Anillin OS=Gallus gallus OX=9031 GN=ANLN PE=4 SV=1 CANONICAL=A0A8V0YR64-1" }, "locus": { "chromosome": "2", "start_pos": 46676891, "end_pos": 46649344, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010040516.1", "url": "https://www.ensembl.org/id/ENSGALT00010040516.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023521.1", "url": "https://www.ensembl.org/id/ENSGALP00010023521.1" } ] } }, { "isoform_ac": "A0A8V0Z4M9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YR64/entry#A0A8V0Z4M9-1", "sequence": { "sequence": "MDPFTEKLLERTRARRENLQKKMAERPTMAARLAAQTKRAREPLLETSNQTSLPDGEVKPTKPSPSKRRCSNNKETEASTIENTQPLPSSSPSHRSPVMNSELHGTVCNKASPAQSLEKGKTSTKSETPATLSVKTRMQKLAEQRRCWDSEDPSECARLSPLQSKALSVSPPKQATNDLASGTPIGRRGRLANLAATIGSWEDDLSHPSAKQNNAQEQPGTTCLSKLSTTSGASARINSSSVKQEAASCSQRLVEASINKPANSKIADPNNSITQSSSSTVPASKKSEVPQQITENPCSPQKTEKRTQTVQSTLSQSVQSREETVKGTHVQPEPKDKPTTPGGSGIKSFLERFGERCQENSARSPSTNTPGYRTPIVTPNTRTIQEKLLKQNENSSTATLALQLKQERERELACIRGRFDKGNLWSAERSESSKRKLPEAKMDGPSQGSPKRSPRSDTTTSGSAEDTPAGDRPEESPSVESSDAVKCEETDKSSSLMVTQPKSPVEAMPVSKLEQLAKKPNDEVCEVETKAGDEMNSSKVINEIFEILQEDGPDIEKLKKEMSMSLEGESDDDEQEESLNISSMSLLTPLVESVGPEVFVSPSKSVGEDSSVSDVSQKSDKFQRTKVPRAESGDSMSSLSEDRSLPYSVDAYRSQRFKETDRPSIKQVIVRKEDVASKLEMKKNGPCDQVNIKKKMQELNNEINMQQTVIYQASQALNCCFDEEHGKGSQEEAEAERLLLLATEKRTALLEELNKLKIEGPLVKRSKAASVSSEFSPSRGSVSISEMRLPLKADFVCGTVQKPEAANYYYVIILRSGAENMVATPLASTASSLNGDALTFTTTFTMHDVSNDFEINIEVYSLVQRKEAPSTDKKKKANKSKVITPKRLLTSITSKSTLLTPAMASPGGPNAVRTTNFILVGTHKLSLSSVGHAKFALDKTMFEDVSGFGAWHRRWCVLSGNCISYWTYPDDEKRKHPLGRINLANCTNRQIEPVNREFCARPNTFELITVRPQREDDKETLVSQCRDTLCVTKNWLSADTKEERNLWMQKLNQVLVDLRMWQPDACYKPIGKL", "length": 1073, "header": "tr|A0A8V0Z4M9-1|A0A8V0Z4M9_CHICK Computationally mapped isoform of Anillin OS=Gallus gallus OX=9031 GN=ANLN PE=4 SV=1 CANONICAL=A0A8V0YR64-1" }, "locus": { "chromosome": "2", "start_pos": 46676891, "end_pos": 46649344, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010040496.1", "url": "https://www.ensembl.org/id/ENSGALT00010040496.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023504.1", "url": "https://www.ensembl.org/id/ENSGALP00010023504.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:420738", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420738", "resource": "KEGG Pathway" }, { "id": "R-GGA-8980692", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8980692", "resource": "Reactome", "description": "RHOA GTPase cycle" }, { "id": "R-GGA-9013026", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013026", "resource": "Reactome", "description": "RHOB GTPase cycle" }, { "id": "R-GGA-9013106", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013106", "resource": "Reactome", "description": "RHOC GTPase cycle" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A286Y917-1", "protein_name": "Anillin", "gene_name": "anln", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDPFTEKLLERTRARRENLQKKMAERPTAANRPMAKRTREPLTDTNSVLSEPTIEKALPSSKPSPFKRRCSDENTFLAGEENKQPVAPQMTDPMTDQKPPLAPTTVRPIPVEQRSAPDMLPTRPPPETEKMVVCPPQSPAKRTDNVLRQKGLDGARETQKEAPTTFPSSMRSRLQRLAGQRQNWDSNGATEAVSESVVVSPLKSHNLDHPPATPTNSEVPVGRKGRLANLAATIGSWEDDLGHPPIRRDNAQAQPGTAYVRPPVSTVTSNSEQLQSARPTSHRPVNRGQQPAVYSPVKSTSVVPPSPQKTEFPQARWAQAVPSPVSSPLKIPPSTQPSSPLKSVTASPSSPHRGYVSQSPLKSHGQVDKLNFGAALNSSPAKPVLAPKPSAADDAVSRVRFTKDATPTQHRGPAATPGGVKSFLERFGERCQERNQNTPSMLGGPGHTSAASTPATPKFKLLQERLGGAQATSTTAALTEKQKMEREAELAQIRNRFQKGNMLRGKEDISEVKDDTENKEIELSLQSQTSLPLHDNKPSVHVPEVFNSPSKSIGKGMSCASSSPAKEIELKVEMPTVEEPEDVQEVDVVREIEMNVDASVNSEVINELFDGVLEESDEDADEDPLNISSMSLLAPLAETVAAVIKSPERKPMTSTPANSFLVKSSTPENPSRPSKFQRTRMLRADSSDSIDVLDEQQNQKLLYSIDAYRSTRVKSEPERPHVKQVIVRKEDVSQRMEMNGSSSHINIKQKMKMLTNEMNLQQTVIHQASQALNCCTDEEHGKGSQVEAEAERLLIIATERRAALKAELDRLKAEGPTAQKKSASSVPVDIGLPASKGSISLLELRLPLKADFICSSANKPECGNHYFFVMIRAGPENTVATPLSSTRTGLSGDALTFTTTFTLSDVSNDFEIDIEVYCLVQKRELNPDKRKKASKSKAITPKRFLNISKSNLQTPVMASPGGPNAVRTSSFVLVGSHKLTLASIGKNKFPLEKIKYERSERELLSDMFHNKVPFLCPLEGHVYLKMQCEVGSRIEEKGFLTMFEDVSGFGAWHRRWCVLSGYCISYWTYPDDEKRKNPMGRINLANCTSRKVEPANREFCARPNTFELITVRPQREDDRETLVSRCKDTLCVTKNWLSADTKDERNLWMQKLNQILVDLRMWQPDSCYRPM", "length": 1171 }, "evidence": [ { "id": "A0A8V0YR64", "url": "https://omabrowser.org/oma/group/A0A8V0YR64/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A5G2R9P5-1", "protein_name": "Anillin", "gene_name": "ANLN", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDPFTEKLLERTRARRENLQRKMAERPIPAARSMTHAKRVREPLSEASNQQPLSGGEEKSCTKPSPSKKRCSDNTEVEVSNLENEKPIESASAKPCSPGTVSPQAQPQAPAPASDSVAAPASLLGMRRGLNSRLEATAASSVKTRMQKLAEQRRHWDSDDVTDDVPESSHVSALPSEEKAASPPKPSLSAASATPVGRRGRLADLAATICSWEDDVKNSSAKQNSVQEQPGTTCLSKFSSASGASAGINSSSVKQEATCCSQRDGDASLNKASSSSAVGASLINGAISSTVKATSSPVKSSTTSVIGAKNCEVQNPELLQKTPVSPLKTEASKPIEKSTVSRTVRPKEELNREVCLQSQSKDKATTPGGTGIKPFLERFGERCQEHSKESPARSTPHRTPVITPNTKAIQERLFKQNASSSTTHLAQQLKQERQKELACLRGRFDKGNLWSAEKGENSRSKQLETKQEIPCQNTPLKKSQVNPNTPSLPGTEKVTENQTPTKTSSTEPTGFSECEMMKSSPLKITLFLEEEKSLKVTSDPKVEQQTEVVREIEMSVDDDDDINSSKVINDIFSDVLEEGELDVEKSQEEMDQADADSSEEQEDALNISSMSLLAPLAQTVGVVSPESLVSSPRLELKDTSVSDESPKPGKFQRTRVPRAESGDSIGSEDRDLPYSIDAYRSQRVKEIDRPSIKQVIVRKEDVTSKLDEKKNGFPCQVNIKQKMQELNNEINLQQTVIYQASQALNCCVDEEHGKGSLEEAEAERLLLIATEKRTLLIDELNKLKNEGPQRKNKASPTSQSEFVPSKGSITLSEIRLPLKADFVCSTIQKPDAANYYFLIILKAGAENMVATPLASTSNSLNGDALTFSTTFTLQDVSNDFEINIEVYSLVQKKDPSGPDKKKKAYKSKAITPKRLLTSITTKSTLPSSVMASLNAVRTSSFALVGSYTLSLSSVGNTKFALDKVPFLSPLEGHIYLKIKCQVNSSVEERGFLTIFEDVSGFGAWHRRWCVLSGNCISYWTYPDDEKRKNPIGRLNLANCTSRQIEPANREFCARRNTFELITVRPQREDDRETLVSQCRDTLCVTKNWLSADTKEERDLWMQKLNQVLVDIRLWQPDACYKPIGKP", "length": 1126 }, "evidence": [ { "id": "A0A8V0YR64", "url": "https://omabrowser.org/oma/group/A0A8V0YR64/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8I6AE50-1", "protein_name": "Anillin", "gene_name": "Anln", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDPFTEKLLERTRARRENLQRKMAERPTAAARSAPHAKRGREPLSEASNQQQPLLAGGEEKSCTKPSPSKKRCSDKIEVEASDLENKEPVDAAKPCSPKPAPRQMKPPAPAAISDSVAAPASLLSTGKASTTSSVKTRMQKLAEQRRHWDSEITDDVSESSHFSPMPSEEKPASPSKPPVSNASATPVGRRGRLANLAATICSWEDDVSYSSAKQNSVQEQPGTACLSKSSSASGPSASINSSSVQQEATCCSQRDGNASVKKDPTSNAADGPLLKASVSSPVKASSSPVRSAPFITRNCEVQSPELLHKTVSPLKTEVLKPCEKPTLSQALQPKEGANKEVCLQSQSKDKLATPGGRGIKPFLERFGERCQEHSKESPTCRAFHRTPNITPNTKAIQERLFKQNTCSSTTHLAQQLKQEREKELACLRGRFDKGSLWSAEKDEKSRSKQLETKQEVHCQNSPLKKHQIVSGTPSTSVSDKVAETPTAVKISGTEPAGSTESEMTKSSPLKITLFLEEEKSLKVASDPEVEQKTEAVHEVEMSVDDEDINSSKVINDIFSDVLEEGELDVEKSQEEMDQVGTESSEEQEDVLNISSMSLLAPLAQTVGVVNLQNVISSPELELRDSSLSAPSPKPGKFQRTRVPRAESGDSLSSEDRDLLYSIDAYRSQRFKETERPSIKQVIVRKEDVTSKLSEKNGVFSGQVNIKQKMQELNNDINLQQTVIYQASQALNCCVDEEHGKGSLEEAEAERLLLIATEKRALLIDELNKLKSEGPQRRNKTAVASQSGFAPSKGSVTLSEICLPLKAEFVCSTAQKPESSNYYYLIMLKAGAEQMVATPLASTANSLSGDALTFPTTFTLNDVSNDFEINVEVYSLVQKKDSSGPEKKKKASKSKAITPKRLLTSITSKSSLHASVMASPGGLSAVRTSNFTLVGSHTLSLSSVGDTKFALDKINFDVREQELLGYLFQEKVPFLSPLEGHICLKISCQVTSTVEEKGFLTIFEDVSGFGAWHRRWCVLSGNCISYWTYPDDERRKNPIGRINLANCISHQIEPANREFCARRNTLELITVRPQREDDRETLVSQCRDTLCVTKNWLSADTKEERDLWMQKLNQVIVDIRLWQPDACYKPVRKP", "length": 1134 }, "evidence": [ { "id": "A0A8V0YR64", "url": "https://omabrowser.org/oma/group/A0A8V0YR64/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8K298-1", "protein_name": "Anillin", "gene_name": "Anln", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDPFTEKLLERTRARRENLQRKMAERPTAVARSAPHAKRGREPLSEASNQQQPLPGGEEKSCTKPSPSKKRCSDKIEVGAPDLENTEPIDVAKPCSPMPAPRQAKPPAPAAISESVAAPAALLSADRGLNSGSEASATSSVKTRMQRLAEQRRHWDSDLTDDVSESSYFAPVPTEDKAASPSKPPISNASATPVGRRGRLANLAATICSWEDDVSHSSAKQNSVQEQPGTACLSKSSSASGASASINSSSVQQEATCCSPRDGNASVRKDPSSNAAHGPLLSASVSSSVKASSPVTAATFITENREAQNPELLHKTASPLKTEARKPCEKPTLSQGAQPKEEANREVCLQSQSKDKLATPGGRGIKPFLERFGERCQEHSKESPSYRASHKTPNITPNTKAIQERLFKQNTCSSTTHLAQQLKQEREKELACLRGRLDKGNLWSAEKNEKSRSKHLETKQEVHCQNTPLKKHQTVASTPLTSVTDKVAENEPAVKLSSTEPAGSTESEMTKSSPLKITLFLEEEKSLKVASDLEVEQNTEAVREVEMSVDDEDINSSRVINDIFSDVLEEGELDVEKSQEEMDQVGAENSEEQEDALNISSMSLLAPLAQTVGVVSLENVISSPPSELRDSNLSAASPKPGKFQRTRVPRAESADSLGSEDRDLLYSIDAYRSQRFKETERPSIKQVIVRKEDVTSKLGEKKNVFSGQVNIKQKMQELNNDINLQQTVIYQASQALNCCVDEEHGKGSLEEAEAERLLLIATEKRALLIDELNKLKSEGPQRRNKTSVISQSEFAPSKGSVTLSEICLPLKADFVCSTAQKTDASNYYYLIMLKAGAEQMVATPLASTANSLSGDALTFPTTFTLHDVSNDFEINIEVYSLVQKKDSLGPDKKKKASKSKAITPKRLLTSITSKSSLHSSVMASPGGLGAVRTSNFTLVGSHTLSLSSVGDTKFALDKVPFLSPLEGHICLKISCQVNSAVEEKGFLTIFEDVSGFGAWHRRWCVLSGNCISYWTYPDDERRKNPIGRINLANCISHQIEPANREFCARRNTLELITVRPQREDDRETLVSQCRDTLCVTKNWLSADTKEERDLWMQKLNQVIVDIRLWQPDACYKPVGKP", "length": 1121 }, "evidence": [ { "id": "A0A8V0YR64", "url": "https://omabrowser.org/oma/group/A0A8V0YR64/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9NQW6-1", "protein_name": "Anillin", "gene_name": "ANLN", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDPFTEKLLERTRARRENLQRKMAERPTAAPRSMTHAKRARQPLSEASNQQPLSGGEEKSCTKPSPSKKRCSDNTEVEVSNLENKQPVESTSAKSCSPSPVSPQVQPQAADTISDSVAVPASLLGMRRGLNSRLEATAASSVKTRMQKLAEQRRRWDNDDMTDDIPESSLFSPMPSEEKAASPPRPLLSNASATPVGRRGRLANLAATICSWEDDVNHSFAKQNSVQEQPGTACLSKFSSASGASARINSSSVKQEATFCSQRDGDASLNKALSSSADDASLVNASISSSVKATSPVKSTTSITDAKSCEGQNPELLPKTPISPLKTGVSKPIVKSTLSQTVPSKGELSREICLQSQSKDKSTTPGGTGIKPFLERFGERCQEHSKESPARSTPHRTPIITPNTKAIQERLFKQDTSSSTTHLAQQLKQERQKELACLRGRFDKGNIWSAEKGGNSKSKQLETKQETHCQSTPLKKHQGVSKTQSLPVTEKVTENQIPAKNSSTEPKGFTECEMTKSSPLKITLFLEEDKSLKVTSDPKVEQKIEVIREIEMSVDDDDINSSKVINDLFSDVLEEGELDMEKSQEEMDQALAESSEEQEDALNISSMSLLAPLAQTVGVVSPESLVSTPRLELKDTSRSDESPKPGKFQRTRVPRAESGDSLGSEDRDLLYSIDAYRSQRFKETERPSIKQVIVRKEDVTSKLDEKNNAFPCQVNIKQKMQELNNEINMQQTVIYQASQALNCCVDEEHGKGSLEEAEAERLLLIATGKRTLLIDELNKLKNEGPQRKNKASPQSEFMPSKGSVTLSEIRLPLKADFVCSTVQKPDAANYYYLIILKAGAENMVATPLASTSNSLNGDALTFTTTFTLQDVSNDFEINIEVYSLVQKKDPSGLDKKKKTSKSKAITPKRLLTSITTKSNIHSSVMASPGGLSAVRTSNFALVGSYTLSLSSVGNTKFVLDKVPFLSSLEGHIYLKIKCQVNSSVEERGFLTIFEDVSGFGAWHRRWCVLSGNCISYWTYPDDEKRKNPIGRINLANCTSRQIEPANREFCARRNTFELITVRPQREDDRETLVSQCRDTLCVTKNWLSADTKEERDLWMQKLNQVLVDIRLWQPDACYKPIGKP", "length": 1124 }, "evidence": [ { "id": "A0A8V0YR64", "url": "https://omabrowser.org/oma/group/A0A8V0YR64/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "actin binding", "id": "GO:0003779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003779", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YR64", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YR64" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YR64", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YR64" } ], "pmid": "" }, { "name": "midbody", "id": "GO:0030496", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030496", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YR64", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YR64" } ], "pmid": "" }, { "name": "actomyosin contractile ring", "id": "GO:0005826", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005826", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YR64", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YR64" } ], "pmid": "" }, { "name": "bleb", "id": "GO:0032059", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032059", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YR64", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YR64" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "mitotic cytokinesis", "id": "GO:0000281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000281", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YR64", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YR64" } ], "pmid": "" }, { "name": "podocyte cell migration", "id": "GO:0090521", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090521", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YR64", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YR64" } ], "pmid": "" }, { "name": "positive regulation of bleb assembly", "id": "GO:1904172", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904172", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YR64", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YR64" } ], "pmid": "" }, { "name": "actomyosin contractile ring assembly", "id": "GO:0000915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000915", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YR64", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YR64" } ], "pmid": "" }, { "name": "septin ring organization", "id": "GO:0031106", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031106", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YR64", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YR64" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1032, "end_pos": 1034, "annotation": 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"ENSGALG00010015135", "url": "https://www.ensembl.org/id/ENSGALG00010015135" } ] } } ], "crossref": [ { "id": "A0A8V0YR98", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YR98", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR028127", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028127", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YR98", "url": "https://www.orthodb.org/?gene=A0A8V0YR98", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16770", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16770", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16770:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16770:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF14998", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14998", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YR98", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YR98", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YR98-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YR98-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEAAACCLPLRRLPLPTAGACPAPGLQQGGRTKPLWRPWLPQEEYMTRRQREQMDTAQPLDAAGDHSSDKALALFRHPVRLLWPKSRCFDYLYSVGEKLLENFPVQATLCLYDDSDSEGDEAEDDDEDGDEGNEGEAGGAVAAVGAGSPRPA", "length": 152, "header": "tr|A0A8V0YR98-1|A0A8V0YR98_CHICK Isoform 1 of Ripply transcriptional repressor 1 OS=Gallus gallus OX=9031 GN=RIPPLY1 PE=3 SV=1 CANONICAL=A0A8V0YR98-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YR98-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YR98/entry#A0A8V0YR98-1", "sequence": { "sequence": "MEAAACCLPLRRLPLPTAGACPAPGLQQGGRTKPLWRPWLPQEEYMTRRQREQMDTAQPLDAAGDHSSDKALALFRHPVRLLWPKSRCFDYLYSVGEKLLENFPVQATLCLYDDSDSEGDEAEDDDEDGDEGNEGEAGGAVAAVGAGSPRPA", "length": 152, "header": "tr|A0A8V0YR98-1|A0A8V0YR98_CHICK Isoform 1 of Ripply transcriptional repressor 1 OS=Gallus gallus OX=9031 GN=RIPPLY1 PE=3 SV=1 CANONICAL=A0A8V0YR98-1" }, "locus": { "chromosome": "4", "start_pos": 10895302, "end_pos": 10893813, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010036459.1", "url": "https://www.ensembl.org/id/ENSGALT00010036459.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021219.1", "url": "https://www.ensembl.org/id/ENSGALP00010021219.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YR98", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YR98" } ], "pmid": "" }, { "name": "embryonic pattern specification", "id": "GO:0009880", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009880", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YR98", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YR98" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YR98", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YR98" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YRA3-1", "uniprot_ac": "A0A8V0YRA3", "uniprot_id": "A0A8V0YRA3_CHICK", "mass": { "chemical_mass": 64979.0, "monoisotopic_mass": 64979.0 }, "refseq": {}, "gene_names": [ { "name": "SYTL1", "type": "recommended", "evidence": [ { "id": "A0A8V0YRA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRA3" } ] } ], "protein_names": [ { "name": "Synaptotagmin-like protein 1", "type": "recommended", "evidence": [ { "id": "A0A8V0YRA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRA3/entry#names_and_taxonomy" } ] }, { "name": "Exophilin-7", "type": "synonym", "evidence": [ { "id": "A0A8V0YRA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRA3/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YRA3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRA3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SYTL1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRA3", "locus": { "chromosome": "23", "start_pos": 2308686, "end_pos": 2300303, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010016809", "url": "https://www.ensembl.org/id/ENSGALG00010016809" } ] } } ], "crossref": [ { "id": "A0A8V0YRA3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YRA3", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd04020", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04020", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd08393", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd08393", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000008", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000008", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR010911", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010911", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035892", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035892", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043567", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043567", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YRA3", "url": "https://www.orthodb.org/?gene=A0A8V0YRA3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YXN4", "url": "https://www.orthodb.org/?gene=A0A8V0YXN4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YY26", "url": "https://www.orthodb.org/?gene=A0A8V0YY26", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YZJ5", "url": "https://www.orthodb.org/?gene=A0A8V0YZJ5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45716", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45716", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45716:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45716:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00168", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00168", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YRA3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRA3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YRA3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRA3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YXN4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXN4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YXN4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXN4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YY26", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YY26", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YY26-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YY26-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YZJ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZJ5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YZJ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZJ5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MELELLDLSFLTEAERCAIAEVLHRDALLRRTEEGRVSKLRQSESDPVRLRTLTGEWFCDVRAQRHQNLLGSDLVRASIRRRRRPWGVAELECGLSRGELEAIREWLLEEKEDEEGAREESPNEDGVPAAAEPQPDPTAPEGTAVSPSAQHGDVPAGEQDGPGQPGDVGLQGKAMGIEGKRGLPSSHIHSSLRWDPRPHCAPAGDGVDGNPFGTSSVEEDEEEPNAAHSSPGVVQGTEPPPAGRTSPQDGRSPPCAALSSSSSISSLSSSTPSGSLLSLYSDSELRRVAVRGCVQFSLRYEAAAQELRVHVVRCRQLAEAKRQRSDPYIKTYLLPDKSNRSKRKTSVRKRSLDPVFNETLKYNVRKAELRGRTLNLSVWHHDALGRNLFLGEVEVPLGEWDWANTRPEWFNLQPRTPIPTDSLPNRGHLNLALKFIPAGSEGSGQPPTGELHIWVKAAQGLVPLHGSTVDAFVQCSVLPDDSKAGRQKTRVVKRSLSPIFNHTMVYDGFQPHDLAQACAECTLWHRDAFAKRQLGGLRLSLGTGSSYGLPVGWMDSTAEERALWGRVLRESGRWVEALLPLRTDLVPRTAP", "length": 591, "header": "tr|A0A8V0YRA3-1|A0A8V0YRA3_CHICK Isoform 1 of Synaptotagmin-like protein 1 OS=Gallus gallus OX=9031 GN=SYTL1 PE=4 SV=1 CANONICAL=A0A8V0YRA3-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YRA3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRA3/entry#A0A8V0YRA3-1", "sequence": { "sequence": "MELELLDLSFLTEAERCAIAEVLHRDALLRRTEEGRVSKLRQSESDPVRLRTLTGEWFCDVRAQRHQNLLGSDLVRASIRRRRRPWGVAELECGLSRGELEAIREWLLEEKEDEEGAREESPNEDGVPAAAEPQPDPTAPEGTAVSPSAQHGDVPAGEQDGPGQPGDVGLQGKAMGIEGKRGLPSSHIHSSLRWDPRPHCAPAGDGVDGNPFGTSSVEEDEEEPNAAHSSPGVVQGTEPPPAGRTSPQDGRSPPCAALSSSSSISSLSSSTPSGSLLSLYSDSELRRVAVRGCVQFSLRYEAAAQELRVHVVRCRQLAEAKRQRSDPYIKTYLLPDKSNRSKRKTSVRKRSLDPVFNETLKYNVRKAELRGRTLNLSVWHHDALGRNLFLGEVEVPLGEWDWANTRPEWFNLQPRTPIPTDSLPNRGHLNLALKFIPAGSEGSGQPPTGELHIWVKAAQGLVPLHGSTVDAFVQCSVLPDDSKAGRQKTRVVKRSLSPIFNHTMVYDGFQPHDLAQACAECTLWHRDAFAKRQLGGLRLSLGTGSSYGLPVGWMDSTAEERALWGRVLRESGRWVEALLPLRTDLVPRTAP", "length": 591, "header": "tr|A0A8V0YRA3-1|A0A8V0YRA3_CHICK Isoform 1 of Synaptotagmin-like protein 1 OS=Gallus gallus OX=9031 GN=SYTL1 PE=4 SV=1 CANONICAL=A0A8V0YRA3-1" }, "locus": { "chromosome": "23", "start_pos": 2308551, "end_pos": 2302251, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010040568.1", "url": "https://www.ensembl.org/id/ENSGALT00010040568.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023554.1", "url": "https://www.ensembl.org/id/ENSGALP00010023554.1" } ] } }, { "isoform_ac": "A0A8V0YXN4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRA3/entry#A0A8V0YXN4-1", "sequence": { "sequence": "MELELLDLSFLTEAERCAIAEVLHRDALLRRTEEGRVSKLRQSESDPVRLRTLTGEWFCDVRAQRHQNLLGSDLVRASIRRRRRPWGVAELECGLSRGELEAIREWLLEEKEDEEGAREESPNEDGVPAAAEPQPDPTAPEGTAVSPSAQHGDVPAGEQDGPGQPGDGVDGNPFGTSSVEEDEEEPNAAHSSPGVVQGTEPPPAGRTSPQDGRSPPCAALSSSSSISSLSSSTPSGSLLSLYSDSELRRVAVRGCVQFSLRYEAAAQELRVHVVRCRQLAEAKRQRSDPYIKTYLLPDKSNRSKRKTSVRKRSLDPVFNETLKYNVRKAELRGRTLNLSVWHHDALGRNLFLGEVEVPLGEWDWANTRPEWFNLQPRTPIPTDSLPNRGHLNLALKFIPAGSEGSGQPPTGELHIWVKAAQGLVPLHGSTVDAFVQCSVLPDDSKAGRQKTRVVKRSLSPIFNHTMVYDGFQPHDLAQACAECTLWHRDAFAKRQLGGLRLSLGTGEGGWRAGGVL", "length": 516, "header": "tr|A0A8V0YXN4-1|A0A8V0YXN4_CHICK Computationally mapped isoform of Synaptotagmin like 1 OS=Gallus gallus OX=9031 GN=SYTL1 PE=4 SV=1 CANONICAL=A0A8V0YRA3-1" }, "locus": { "chromosome": "23", "start_pos": 2307134, "end_pos": 2302251, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010040564.1", "url": "https://www.ensembl.org/id/ENSGALT00010040564.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023551.1", "url": "https://www.ensembl.org/id/ENSGALP00010023551.1" } ] } }, { "isoform_ac": "A0A8V0YY26-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRA3/entry#A0A8V0YY26-1", "sequence": { "sequence": "WISSGFGRWAPPRARSTHGAGAAGPQLPDRGGALRHRRSAAPRRSAAPHGGGPRQHPELSGAPRPSSKLRQSESDPVRLRTLTGEWFCDVRAQRHQNLLGSDLVRASIRRRRRPWGVAELECGLSRGELEAIREWLLEEKEDEEGAREESPNEDGVPAAAEPQPDPTAPEGTAVSPSAQHGDVPAGEQDGPGQPGDGVDGNPFGTSSVEEDEEEPNAAHSSPGVVQGTEPPPAGRTSPQDGRSPPCAALSSSSSISSLSSSTPSGSLLSLYSDSELRRVAVRGCVQFSLRYEAAAQELRVHVVRCRQLAEAKRQRSDPYIKTYLLPDKSNRSKRKTSVRKRSLDPVFNETLKYNVRKAELRGRTLNLSVWHHDALGRNLFLGEVEVPLGEWDWANTRPEWFNLQPRTPIPTDSLPNRGHLNLALKFIPAGSEGSGQPPTGELHIWVKAAQGLVPLHGSTVDAFVQCSVLPDDSKAGRQKTRVVKRSLSPIFNHTMVYDGFQPHDLAQACAECTLWHRDAFAKRQLGGLRLSLGTGSSYGLPVGWMDSTAEERALWGRVLRESGRWVEALLPLRTDLVPRTAP", "length": 582, "header": "tr|A0A8V0YY26-1|A0A8V0YY26_CHICK Computationally mapped isoform of Synaptotagmin-like protein 1 OS=Gallus gallus OX=9031 GN=SYTL1 PE=4 SV=1 CANONICAL=A0A8V0YRA3-1" }, "locus": { "chromosome": "23", "start_pos": 2308551, "end_pos": 2301183, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010040558.1", "url": "https://www.ensembl.org/id/ENSGALT00010040558.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023548.1", "url": "https://www.ensembl.org/id/ENSGALP00010023548.1" } ] } }, { "isoform_ac": "A0A8V0YZJ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRA3/entry#A0A8V0YZJ5-1", "sequence": { "sequence": "MELELLDLSFLTEAERCAIAEVLHRDALLRRTEEGRVSKLRQSESDPVRLRTLTGEWFCDVRAQRHQNLLGSDLVRASIRRRRRPWGVAELECGLSRGELEAIREWLLEEKEDEEGAREESPNEDGVPAAAEPQPDPTAPEGTAVSPSAQHGDVPAGEQDGPGQPGDGVDGNPFGTSSVEEDEEEPNAAHSSPGVVQPSGSLLSLYSDSELRRVAVRGCVQFSLRYEAAAQELRVHVVRCRQLAEAKRQRSDPYIKTYLLPDKSNRSKRKTSVRKRSLDPVFNETLKYNVRKAELRGRTLNLSVWHHDALGRNLFLGEVEVPLGEWDWANTRPEWFNLQPRTPIPTDSLPNRGHLNLALKFIPAGSEGSGQPPTGELHIWVKAAQGLVPLHGSTVDAFVQCSVLPDDSKAGRQKTRVVKRSLSPIFNHTMVYDGFQPHDLAQACAECTLWHRDAFAKRQLGGLRLSLGTGSSYGLPVGWMDSTAEERALWGRVLRESGRWVEALLPLRTDLVPRTAP", "length": 517, "header": "tr|A0A8V0YZJ5-1|A0A8V0YZJ5_CHICK Computationally mapped isoform of Synaptotagmin-like protein 1 OS=Gallus gallus OX=9031 GN=SYTL1 PE=4 SV=1 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"database": "UniProtKB", "id": "A0A8V0YRA3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRA3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "small GTPase binding", "id": "GO:0031267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031267", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YRA3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRA3" } ], "pmid": "" }, { "name": "neurexin family protein binding", "id": "GO:0042043", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042043", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YRA3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRA3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 339, "end_pos": 341, "annotation": "n_glycosylation_sequon" }, { "start_pos": 357, "end_pos": 359, "annotation": "n_glycosylation_sequon" }, { "start_pos": 375, "end_pos": 377, "annotation": "n_glycosylation_sequon" }, { "start_pos": 501, "end_pos": 503, 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"count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YRB2-1", "uniprot_ac": "A0A8V0YRB2", "uniprot_id": "A0A8V0YRB2_CHICK", "mass": { "chemical_mass": 53696.0, "monoisotopic_mass": 53696.0 }, "refseq": {}, "gene_names": [ { "name": "SAMD7", "type": "recommended", "evidence": [ { "id": "A0A8V0YRB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRB2" } ] } ], "protein_names": [ { "name": "Sterile alpha motif domain containing 7", "type": "synonym", "evidence": [ { "id": "A0A8V0YRB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRB2/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YRB2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRB2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SAMD7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRB2", "locus": { "chromosome": "9", "start_pos": 19601723, "end_pos": 19608140, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010016821", "url": "https://www.ensembl.org/id/ENSGALG00010016821" } ] } } ], "crossref": [ { "id": "A0A8V0YRB2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YRB2", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd09579", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09579", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001660", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001660", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013761", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013761", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050548", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050548", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YRB2", "url": "https://www.orthodb.org/?gene=A0A8V0YRB2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12247", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12247", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12247:SF89", "url": 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"MAVNPQLMGTAQQRMQAIPSQFEPRLVDRDLLPSTEMTATADPRQIHIASHLGPTVPQHSSMPNLLSNRIYPGYGFLQPESMEAVARRQELVQKQNIARMEMEMSAIFQQKEMEKAHRKGLLSLEAPFLYHGMPASPIAFRGRHRLPEGHLPSDLYVHRTTLDELHGNTMLMATSPYPPVSTLQRERGRRPGRRAANHKAADCGANGTKSQTEDKSTDLASTAVDDEKEDKKEAEVETPNKHEQSKNQAEPSAVAKNCKELEQDLRKNCANHEISAEPNSCNNTSEKESNSSCAAFDDKYMYPSAIPFSALPYGFPVPTHGLILNGEDISTIEDIRKWTVDDVYNFIMSLPGCSDYAQTFKDHAIDGETLPLLTEEHLLDTMGLKLGPALKIRSQVSRRLGNVFYMMNLPLSVPLPPAPGKAPEQPPDIASPLRCNSSGDVLDSPCSQGLETSKTVEQIVSESREHPCDADGPQADFQMIAFQKS", "length": 485, "header": "tr|A0A8V0YRB2-1|A0A8V0YRB2_CHICK Isoform 1 of Sterile alpha motif domain containing 7 OS=Gallus gallus OX=9031 GN=SAMD7 PE=4 SV=1 CANONICAL=A0A8V0YRB2-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YRB2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRB2/entry#A0A8V0YRB2-1", "sequence": { "sequence": 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"https://www.ensembl.org/id/ENSGALP00010023564.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 55, "start_aa": "Thr", "end_pos": 55, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr55", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YRB2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRB2" } ], "pmid": "" }, { "name": "DNA-binding transcription repressor activity, RNA polymerase II-specific", "id": "GO:0001227", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001227", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YRB2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRB2" } ], "pmid": "" }, { "name": "histone binding", "id": "GO:0042393", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042393", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YRB2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRB2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YRB2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRB2" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YRB2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRB2" } ], "pmid": "" }, { "name": "PRC1 complex", "id": "GO:0035102", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035102", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YRB2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRB2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "negative regulation of DNA-templated transcription", "id": "GO:0045892", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045892", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YRB2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRB2" } ], "pmid": "" }, { "name": "retinal rod cell development", "id": "GO:0046548", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046548", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YRB2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRB2" } ], "pmid": 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